| <table border="1"> | |
| <tr><td>Year</td><td>Title</td><td>Role</td><td>Notes</td></tr> | |
| <tr><td>1967</td><td>Up the Down Staircase</td><td>Charlotte Wolf</td><td>-</td></tr> | |
| <tr><td>1967</td><td>The Tiger Makes Out</td><td>Lady on Bus</td><td>-</td></tr> | |
| <tr><td>1971</td><td>The Hospital</td><td>Mrs. Cushing</td><td>-</td></tr> | |
| <tr><td>1973</td><td>Two People</td><td>Mrs. McCluskey</td><td>-</td></tr> | |
| <tr><td>1978</td><td>Fedora</td><td>Miss Balfour</td><td>-</td></tr> | |
| <tr><td>1979</td><td>Starting Over</td><td>Marva Potter</td><td>-</td></tr> | |
| <tr><td>1981</td><td>Outland</td><td>Dr. Marian Lazarus</td><td>Saturn Award for Best Supporting Actress</td></tr> | |
| <tr><td>1983</td><td>Independence Day</td><td>Carla Taylor</td><td>-</td></tr> | |
| <tr><td>1983</td><td>Romantic Comedy</td><td>Blanche Dailey</td><td>-</td></tr> | |
| <tr><td>1986</td><td>Resting Place</td><td>Eudora McCallister</td><td>-</td></tr> | |
| <tr><td>1988</td><td>Bright Lights, Big City</td><td>Clara</td><td>-</td></tr> | |
| <tr><td>1989</td><td>Communion</td><td>Dr. Janet Duffy</td><td>-</td></tr> | |
| <tr><td>1989</td><td>See You in the Morning</td><td>Neenie</td><td>-</td></tr> | |
| <tr><td>1990</td><td>Sibling Rivalry</td><td>Rose Turner</td><td>-</td></tr> | |
| <tr><td>1990</td><td>Misery</td><td>Virginia</td><td>Nominated—Saturn Award for Best Supporting Actress</td></tr> | |
| <tr><td>1991</td><td>Doc Hollywood</td><td>Lillian</td><td>-</td></tr> | |
| <tr><td>1991</td><td>Walking the Dog</td><td>Antique Dealer</td><td>Short film</td></tr> | |
| <tr><td>1992</td><td>Raising Cain</td><td>Dr. Lynn Waldheim</td><td>Nominated—Saturn Award for Best Supporting Actress</td></tr> | |
| <tr><td>1998</td><td>It All Came True</td><td>Amy</td><td>-</td></tr> | |
| <tr><td>2000</td><td>Midnight Gospel</td><td>Ruth</td><td>Short film</td></tr> | |
| <tr><td>2001</td><td>Landfall</td><td>Emily Thornton</td><td>-</td></tr> | |
| <tr><td>2001</td><td>The Rising Place</td><td>Ruth Wilder</td><td>-</td></tr> | |
| <tr><td>2002</td><td>Highway</td><td>Mrs. Murray</td><td>-</td></tr> | |
| <tr><td>2007</td><td>The Mist</td><td>Irene Reppler</td><td>-</td></tr> | |
| <tr><td>2009</td><td>Julie & Julia</td><td>Irma Rombauer</td><td>-</td></tr> | |
| <tr><td>2011</td><td>Dolphin Tale</td><td>Gloria Forrest</td><td>-</td></tr> | |
| <tr><td>2014</td><td>And So It Goes</td><td>Claire</td><td>-</td></tr> | |
| </table> | |