| Year | Nominated work | Category | Result | Notes |
| 1985 | Neuromancer | Hugo Award for Best Novel | Won | — |
| 1986 | "Dogfight" | Hugo Award for Best Novelette | Nominated | Co-authored with Michael Swanwick |
| 1987 | "The Winter Market" | Hugo Award for Best Novelette | Nominated | — |
| 1987 | Count Zero | Hugo Award for Best Novel | Nominated | — |
| 1989 | Mona Lisa Overdrive | Hugo Award for Best Novel | Nominated | — |
| 1994 | Virtual Light | Hugo Award for Best Novel | Nominated | — |