Datasets:
Modalities:
Text
Formats:
parquet
Languages:
English
Size:
100K - 1M
Tags:
medical
biomedicine
clinical-trials
large-language-models
supervised-finetuning
evidence-based-medicine
License:
Create README.md
Browse files
README.md
ADDED
|
@@ -0,0 +1,129 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
---
|
| 2 |
+
license: apache-2.0
|
| 3 |
+
language:
|
| 4 |
+
- en
|
| 5 |
+
tags:
|
| 6 |
+
- medical
|
| 7 |
+
- biomedicine
|
| 8 |
+
- clinical-trials
|
| 9 |
+
- large-language-models
|
| 10 |
+
- supervised-finetuning
|
| 11 |
+
- evidence-based-medicine
|
| 12 |
+
- trial-design
|
| 13 |
+
- systematic-review
|
| 14 |
+
|
| 15 |
+
config_names:
|
| 16 |
+
- study_search
|
| 17 |
+
- study_screening
|
| 18 |
+
- evidence_summarization
|
| 19 |
+
- trial_design
|
| 20 |
+
- sample_size_estimation
|
| 21 |
+
- trial_completion_assessment
|
| 22 |
+
|
| 23 |
+
configs:
|
| 24 |
+
- config_name: study_search
|
| 25 |
+
data_files:
|
| 26 |
+
- split: train
|
| 27 |
+
path: sft_study_search_data_cleaned.parquet
|
| 28 |
+
|
| 29 |
+
- config_name: study_screening
|
| 30 |
+
data_files:
|
| 31 |
+
- split: train
|
| 32 |
+
path: sft_study_screening_data.parquet
|
| 33 |
+
|
| 34 |
+
- config_name: evidence_summarization
|
| 35 |
+
data_files:
|
| 36 |
+
- split: train
|
| 37 |
+
path: sft_evidence_summarization_data.parquet
|
| 38 |
+
|
| 39 |
+
- config_name: trial_design
|
| 40 |
+
data_files:
|
| 41 |
+
- split: train
|
| 42 |
+
path: sft_design_data.parquet
|
| 43 |
+
|
| 44 |
+
- config_name: sample_size_estimation
|
| 45 |
+
data_files:
|
| 46 |
+
- split: train
|
| 47 |
+
path: sft_sample_size_data.parquet
|
| 48 |
+
|
| 49 |
+
- config_name: trial_completion_assessment
|
| 50 |
+
data_files:
|
| 51 |
+
- split: train
|
| 52 |
+
path: sft_trial_completion_assessment_data.parquet
|
| 53 |
+
---
|
| 54 |
+
# TrialPanorama: Supervised Fine-Tuning Data for Clinical Research LLMs
|
| 55 |
+
|
| 56 |
+
## Dataset Summary
|
| 57 |
+
|
| 58 |
+
**TrialPanorama SFT** is a large-scale, task-oriented **supervised fine-tuning (SFT) dataset** designed to train large language models for **end-to-end clinical research and trial development workflows**.
|
| 59 |
+
|
| 60 |
+
The dataset is derived from **TrialPanorama**, a structured clinical research resource aggregating **1.6M+ clinical trial records** across global registries and linking them with biomedical ontologies and supporting literature. It focuses on transforming raw clinical trial data and curated evidence into **instruction–response pairs** that reflect realistic, expert-level research tasks.
|
| 61 |
+
|
| 62 |
+
The dataset supports training LLMs to operate as **clinical research assistants** capable of systematic literature review, trial design reasoning, and evidence-based decision making.
|
| 63 |
+
|
| 64 |
+
---
|
| 65 |
+
|
| 66 |
+
## Supported Training Tasks
|
| 67 |
+
|
| 68 |
+
Each task is released as a separate dataset configuration.
|
| 69 |
+
|
| 70 |
+
| Task (config) | Description |
|
| 71 |
+
|---|---|
|
| 72 |
+
| `study_search` | Given a clinical research question, retrieve and justify relevant studies from large trial and literature corpora. |
|
| 73 |
+
| `study_screening` | Perform inclusion/exclusion decisions for candidate studies based on eligibility criteria and study metadata. |
|
| 74 |
+
| `evidence_summarization` | Synthesize structured and unstructured trial evidence into concise, faithful summaries. |
|
| 75 |
+
| `trial_design` | Generate or refine clinical trial designs, including arms, interventions, and eligibility criteria. |
|
| 76 |
+
| `sample_size_estimation` | Estimate appropriate sample sizes under specified statistical and design assumptions. |
|
| 77 |
+
| `trial_completion_assessment` | Assess trial completion likelihood and rationalize risks using trial design and historical evidence. |
|
| 78 |
+
|
| 79 |
+
---
|
| 80 |
+
|
| 81 |
+
## Data Characteristics
|
| 82 |
+
|
| 83 |
+
- **Instruction-following format** suitable for SFT
|
| 84 |
+
- Grounded in **real clinical trial records**
|
| 85 |
+
- Emphasizes **clinical reasoning**, not surface text generation
|
| 86 |
+
- Covers both **systematic review** and **trial design & optimization** tasks
|
| 87 |
+
- Designed to support **generalist and agentic LLM training**
|
| 88 |
+
|
| 89 |
+
All files are provided in **Apache Parquet** format.
|
| 90 |
+
|
| 91 |
+
---
|
| 92 |
+
|
| 93 |
+
## Typical Fields
|
| 94 |
+
|
| 95 |
+
Each record may include:
|
| 96 |
+
- Task-specific **instruction or prompt**
|
| 97 |
+
- Structured **context** (trial metadata, eligibility criteria, outcomes, phase)
|
| 98 |
+
- **Model response targets** written or validated by domain experts
|
| 99 |
+
- Task and difficulty metadata
|
| 100 |
+
|
| 101 |
+
Exact schemas vary by task.
|
| 102 |
+
|
| 103 |
+
---
|
| 104 |
+
|
| 105 |
+
## Intended Use
|
| 106 |
+
|
| 107 |
+
This dataset is intended for:
|
| 108 |
+
- **Supervised fine-tuning of LLMs** for clinical research tasks
|
| 109 |
+
- Training **research-oriented AI agents** for trial planning and evidence synthesis
|
| 110 |
+
- Building domain-adapted models for **systematic review automation**
|
| 111 |
+
- Academic benchmarking of clinical reasoning capabilities
|
| 112 |
+
|
| 113 |
+
### Not Intended For
|
| 114 |
+
|
| 115 |
+
- Model evaluation (see DeepEvidence benchmarks for evaluation)
|
| 116 |
+
- Clinical decision making
|
| 117 |
+
- Direct medical or regulatory use
|
| 118 |
+
|
| 119 |
+
---
|
| 120 |
+
|
| 121 |
+
## How to Load
|
| 122 |
+
|
| 123 |
+
Load a specific training task via its configuration name:
|
| 124 |
+
|
| 125 |
+
```python
|
| 126 |
+
from datasets import load_dataset
|
| 127 |
+
|
| 128 |
+
ds = load_dataset("zifeng-ai/TrialPanorama-SFT", "study_screening")
|
| 129 |
+
ds["train"]
|