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Importance of the selection of controls in genetic studies of knee osteoarthritis
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: Genome Wide Association studies have provided data on hundreds of thousands polymorphisms for large collections of population controls. They can be used to compare with genotypes of patients with low prevalence diseases and there is abundant experience of the validity of this approach. However, it is unclear t...
0
Femoral fractures in Paget's disease
Management of Hip Fractures in the Elderly
Since the original description of osteitis deformans, the treatment of femoral fractures occurring in this disease process has been difficult. A retrospective study of 35 fractures treated over an 8-year period was undertaken to identify the factors that influenced the results. The fractures were classified according t...
0
Obese Diabetic Patients are at Substantial Risk for Deep Infection after Primary TKA
PJI DX Updated Search
We conducted a prospective study of 1214 consecutive primary TKAs to compare the deep prosthetic infection rate between obese and nonobese patients during the first 12 months after surgery. We also sought to determine whether patient or surgical variables such as comorbidities, age, gender, blood transfusion, use of su...
0
The likelihood of total knee arthroplasty following arthroscopic surgery for osteoarthritis: a systematic review
AMP (Acute Meniscal Pathology)
BACKGROUND: Arthroscopic surgery is a common treatment for knee osteoarthritis (OA), particularly for symptomatic meniscal tear. Many patients with knee OA who have arthroscopies go on to have total knee arthroplasty (TKA). Several individual studies have investigated the interval between knee arthroscopy and TKA. Our ...
0
Cabozantinib in the treatment of metastatic renal cell carcinoma - final data analysis from four oncology centers in the Czech Republic
MSTS 2022 - Metastatic Disease of the Humerus
BACKGROUND: Current standard treatments for patients with metastatic renal cell carcinoma (mRCC) involve tyrosine kinase inhibitors (TKI) that inhibit angiogenesis. Cabozantinib is a multi TKI used for the treatment of mRCC in the first- and second-line setting. PURPOSE: The aim of this study was the final analysis of ...
0
Principles of Open Fracture Management
DoD SSI (Surgical Site Infections)
Open fractures are contaminated wounds that contain gram-positive and gram-negative organisms; therefore, wide-spectrum antibiotic therapy should be incorporated into the treatment plan. Antibiotics should be initiated as soon after injury as possible, preferably within 3 hours of injury, after which time the rate of i...
0
An open-label study to evaluate the safety and efficacy of tissue plasminogen activator in treatment of severe frostbite
DoD LSA (Limb Salvage vs Amputation)
BACKGROUND: Severe frostbite can have devastating consequences with loss of limbs and digits. One of the mechanisms of cold injury to human tissue is vascular thrombosis. The effect of tissue plasminogen activator (tPA) and heparin in limb and digit preservation in severe frostbite patients has not been previously stud...
0
Long-term results of the Accord total knee replacement in the Countess of Chester Hospital
Surgical Management of Osteoarthritis of the Knee CPG
Between 1985 and 1996, 74 knees in 61 patients were replaced with a cemented Accord total knee arthroplasty at the Countess of Chester Hospital. This prosthesis is of an unconstrained meniscal-bearing design. At the time of study, 16 patients with 20 knees had died, six knees were lost to follow-up and one knee had bec...
0
Naproxen in osteoarthrosis. Double-blind crossover trial
OAK 3 - Non-arthroplasty tx of OAK
In this double�blind crossover trial, naproxen (750 mg/day) was compared to placebo for the treatment of osteoarthrosis of the hip and knee. Patients were randomly assigned to treatment with either naproxen or placebo for 4 weeks and then to treatment with the alternate agent for a second 4�week period. 8 out of 9 ...
0
Incidence of surgically treated osteoarthritis in the hip and knee in male construction workers
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: Occupational workload has been associated with an increased risk of osteoarthritis. The objective was to further examine the association between workload and occurrence of osteoarthritis and in particular to study whether heavy workload has similar importance as a causative factor for osteoarthritis of the h...
1
Outcomes in breast reduction surgery
Reduction Mammoplasty for Female Breast Hypertrophy
Previous studies have established that patients with macromastia rate their physical and emotional health as substantially poorer than a control population. The aim of the current study was to confirm this discrepancy, and to evaluate the hypothesis that patients with macromastia who undergo bilateral reduction mammapl...
0
A Cost-Effectiveness Analysis of Reverse Total Shoulder Arthroplasty versus Hemiarthroplasty for the Management of Complex Proximal Humeral Fractures in the Elderly
Hip Fx in the Elderly 2019
BACKGROUND: There is ongoing debate regarding the optimal surgical treatment of complex proximal humeral fractures in elderly patients. OBJECTIVES: To evaluate the cost-effectiveness of reverse total shoulder arthroplasty (RTSA) compared with hemiarthroplasty (HA) in the management of complex proximal humeral fractures...
0
Immediate effects of an elastic knee sleeve on frontal plane gait biomechanics in knee osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
INTRODUCTION: Osteoarthritis of the knee affects millions of people. Elastic knee sleeves aim at relieving symptoms. While symptomatic improvements have been demonstrated as a consequence of elastic knee sleeves, evidence for biomechanical alterations only exists for the sagittal plane. We therefore asked what effect a...
1
Metal-backed acetabular components with conventional polyethylene: A review of 9113 primary components with a follow-up of 20 years
Developmental Dysplasia of the Hip CPG
The Norwegian Arthroplasty Register has shown that several designs of uncemented femoral stems give good or excellent survivorship. The overall findings for uncemented total hip replacement however, have been disappointing because of poor results with the use of metal-backed acetabular components. In this study, we exc...
0
Increased expression levels of apolipoprotein J/clusterin during primary osteoarthritis
Surgical Management of Osteoarthritis of the Knee CPG
Osteoarthritis (OA) is a slowly progressive degenerative joint disease that is associated with joint space narrowing, osteophyte formation and subchondral sclerosis. Despite extensive effort actual breakthroughs in the field of genetic or biochemical biomarkers of OA are limited. As secretory apolipoprotein J/clusterin...
0
Strain distribution in the proximal human femoral metaphysis
Management of Hip Fractures in the Elderly
There is significant interest in the stress-strain state in the proximal femoral metaphysis, because of its relevance for hip fractures and prosthetic replacements. The scope of this work was to provide a better understanding of the strain distribution, and of its correlation with the different directions of loading, a...
0
Could a simple educational intervention modify beliefs about whiplash? A preliminary study among professionals working in a rehabilitation ward
DoD PRF (Psychosocial RF)
Could a simple educational intervention modify beliefs about whiplash? A preliminary study among professionals working in a rehabilitation ward. Objective: Whiplash and its consequences remain an alarming clinical and social problem, and psychosocial factors could play a role. We aimed to translate and assess the effec...
0
Individualization of lymph node dissection in RET (rearranged during transfection) carriers at risk for medullary thyroid cancer: value of pretherapeutic calcitonin levels
MSTS 2018 - Femur Mets and MM
OBJECTIVE: This study sought to define the need for lymph node dissection in Rearranged during Transfection (RET) carriers at risk for hereditary medullary thyroid cancer. SUMMARY BACKGROUND DATA: Controversy surrounds the need for lymph node dissection to complement thyroidectomy in RET carriers. METHODS: Integration ...
1
Comparison of anterior cruciate ligament reconstruction in male and female athletes using the patellar tendon and hamstring autografts
Anterior Cruciate Ligament Injuries CPG
Despite the higher incidence of anterior cruciate ligament (ACL) injuries in female than in male athletes few authors have studied the effects of gender on the outcome of ACL reconstruction. This prospective study compared the results of ACL reconstruction using the patellar tendon and hamstring techniques in men and w...
0
Geriatric distal femoral fractures: A retrospective study of 30 day mortality
Hip Fx in the Elderly 2019
INTRODUCTION: Distal femoral fractures have many of the same challenges as hip fractures, but there has been limited research into outcomes following these. The aim of this study was to assess 30 day mortality following distal femoral fractures in comparison to hip fractures presenting to a single institution Secondary...
0
Incidence of venous thromboembolism following major surgery in Korea: From the Health Insurance Review and Assessment Service database
Surgical Management of Osteoarthritis of the Knee CPG
Background: Data on the incidence of venous thromboembolism (VTE) following major surgery in Asian populations are limited. Methods: Using the Korean Health Insurance Review and Assessment Service database, we performed a nationwide population-based epidemiologic study to estimate the incidence of VTE after major ortho...
0
Implementation of a Novel Remote Physician SBRT Coverage Process during the Coronavirus Pandemic
Coronavirus Disease 2019 (COVID-19)
INTRODUCTION: During the COVID-19 pandemic, alternative methods of care are needed to reduce the relative risk of transmission in departments. Also needed is the ability to provide vital radiation oncological care if radiation oncologists (RO) are reallocated to other departments. We implemented a novel remote RO SBRT ...
0
Comparison of clinical outcomes and second-look arthroscopic findings after ACL reconstruction using a hamstring autograft or a tibialis allograft
OAK 3 - Non-arthroplasty tx of OAK
PURPOSE: The purpose of this prospective randomized clinical study was to compare the clinical and radiological outcomes, including tibial tunnel widening and the progression of osteoarthritis after ACL reconstruction using a hamstring autograft or a tibialis allograft. In addition, we compared the graft tear and synov...
0
Use of recommended non-surgical knee osteoarthritis management in patients prior to totalv knee arthroplasty: a cross-sectional study
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: Our aim was to assess prior use of core recommended non-surgical treatment among patients with knee osteoarthritis (OA) scheduled for total knee arthroplasty (TKA); and, to assess potential patient-level correlates of underuse, if found. METHODS: This was a cross-sectional study of patients undergoing TKA fo...
0
Endothelin-1 is secreted after total knee arthroplasty regardless of the use of a tourniquet
Surgical Management of Osteoarthritis of the Knee CPG
Early infections and wound healing disorders after implantation of a total knee replacement occur regardless of the intraoperative use of a tourniquet. The biochemical regulatory processes responsible for the disturbances in microcirculation and thus the potential therapeutic options have yet to be elucidated. The hypo...
0
Bone disease in long-term dialysis
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
We reviewed the clinical features, laboratory findings, and skeletal abnormalities of six patients who have been on dialysis therapy for 12 to 20 years (average, 16.7 years). Hemodialysis has been the major therapeutic modality in five of the six individuals. Ages of the patients ranged from 28 to 67 years (mean, 44.5)...
0
Total ankle arthroplasty: state of the art
Surgical Management of Osteoarthritis of the Knee CPG
Total ankle arthroplasty results from the 1970s and 1980s were comparatively poor. The outcomes of these surgeries deteriorated rather dramatically with time. Causes of failure were multifactorial, but the 2 features that seemed central to implant failure were constrained designs and cement fixation. Total ankle operat...
1
Quality indicators for the primary care of osteoarthritis: A systematic review
SR for PM on OA of All Extremities
Objective: To identify valid and feasible quality indicators for the primary care of osteoarthritis (OA). Design: Systematic review and narrative synthesis. Data sources: Electronic reference databases (MEDLINE,
0
Posterior Femoral Neck Impingement Secondary to Excess Acetabular Anteversion in Hip Resurfacing Arthroplasty
PJI DX Updated Search
Component malposition in resurfacing arthroplasty can cause impingement, reduced range of motion, increased metal wear, and early failure. It is therefore important that any component malposition is recognized early and monitored carefully. We present a case of delayed diagnosis of excess acetabular component anteversi...
0
Immobilisation of extra-articular distal radius fractures (Colles type) in dorsiflexion: The functional and anatomical outcome
Distal Radius Fractures
Background: Cast immobilisation after successful closed reduction is a standard treatment for displaced extra-articular fractures of lower end radius. The position of the wrist during immobilisation is controversial. Immobilisation in dorsiflexion prevents redisplacement after closed reduction. Our aim is to determine ...
0
Variability of the location of the tibial tubercle affects the rotational alignment of the tibial component in kinematically aligned total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: Our experience with computer plans of kinematically aligned total knee arthroplasty showed that the anteroposterior (AP) axis of the tibial component when viewed in an axial plane did not consistently intersect either the medial border or the medial 1/3 of the tibial tubercle. The purposes were (1) to determin...
0
Long-term outcome after additional catheter-directed thrombolysis versus standard treatment for acute iliofemoral deep vein thrombosis (the CaVenT study): A randomised controlled trial
DOD - Acute Comp Syndrome CPG
Background: Conventional anticoagulant treatment for acute deep vein thrombosis (DVT) effectively prevents thrombus extension and recurrence, but does not dissolve the clot, and many patients develop post-thrombotic syndrome (PTS). We aimed to examine whether additional treatment with catheter-directed thrombolysis (CD...
0
Attempted unreamed nailing in tibial fractures: a prospective consecutive series of 55 patients
DoD SSI (Surgical Site Infections)
We evaluated the possibility of unreamed insertion of an intramedullary nail (IMN) in a consecutive series of 55 tibial shaft fractures in 55 patients (30 men). 43 fractures were closed and 12 fractures were open. All surgeons involved were instructed to try unreamed insertion primarily. Selection of nail diameter was ...
1
Effectiveness and tolerability of tapentadol prolonged release compared with prior opioid therapy for the management of severe, chronic osteoarthritis pain
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: Tapentadol prolonged release (PR; 100-250 mg twice daily) has been efficacious and well tolerated for managing moderate-to-severe, chronic osteoarthritis hip or knee pain in phase 3 studies with washout of previous analgesic treatment. OBJECTIVE: The objective of this study was to evaluate the effectiveness...
0
Prospective Results of Uncemented Tantalum Monoblock Tibia in Total Knee Arthroplasty. Minimum 5-Year Follow-up in Patients Younger Than 55 Years
PJI DX Updated Search
A significant increase in younger patients undergoing total knee arthroplasty raises the theoretical concern for revision secondary to micromotion and fixation failure with cemented components. We prospectively studied 100 consecutive tantalum monoblock uncemented tibial components and 312 concurrent cemented controls....
0
Hip protectors for preventing hip fractures in the elderly
Management of Hip Fractures in the Elderly
BACKGROUND: Hip fracture in the elderly usually results from a fall on the hip. Hip protectors have been advocated as a means to reduce the risk of sustaining a hip fracture. OBJECTIVES: To determine if external hip protectors reduce the incidence of hip fractures in elderly persons following a fall. SEARCH STRATEGY: W...
0
1.0 s Ultrafast MRI in non-sedated infants after reduction with spica casting for developmental dysplasia of the hip: a feasibility study
Developmental Dysplasia of the Hip 2020 Review
PURPOSE: The aim of this study was to first develop and use 1.0 s ultrafast magnetic resonance imaging (MRI) to confirm the location of the femoral head in non-sedated infants with developmental dysplasia of the hip (DDH) after reduction with spica cast application in clinical settings. METHODS: The ultrafast acquisit...
0
Discrepancy of alignment in different weight bearing conditions before and after high tibial osteotomy
OAK 3 - Non-arthroplasty tx of OAK
PURPOSE: To evaluate the differences in the amount of varus malalignment and valgus (over) correction in relation to three different weight bearing conditions from whole leg AP radiographs (single-limb (SL) stance, double-limb (DL) stance, supine position (S)) before and after high tibial osteotomy (HTO), and to evalua...
0
Clinical presentation and arthroscopic treatment of hypermobile Type III Wrisberg variant of lateral discoid meniscus: Report of nine cases
AMP (Acute Meniscal Pathology)
Background: The aim of the present study was to document a series of patients with meniscal hypermobility due to a Type III Wrisberg variant lateral discoid meniscus, describing their clinical presentation, analyzing their magnetic resonance imaging (MRI) and arthroscopic characteristics, and reporting the outcomes of ...
0
Heart rate variability as a predictor of hypotension after spinal anesthesia in hypertensive patients
AAHKS (8) Anesthetic Infiltration
Background: Hypotension is a common phenomenon after spinal anesthesia in hypertensive patients. We investigated whether heart rate variability could predict the occurrence of hypotension after spinal anesthesia in hypertensive patients. Methods: Forty-one patients undergoing spinal anesthesia were included. Heart rate...
0
Percutaneous hamstring lengthening with a Large-Gauge Needle a retrospective study. First results and technic
Surgical Management of Osteoarthritis of the Knee CPG
Introduction.- After injury of the central nervous system or dementia loss of elasticity of the muscle hamstrings (IJ) is frequent. These deformations impact the quality of life of these patients. We have developed a surgical procedure of percutaneous lengthening hamstrings with a Large-Gauge. Method.- Retrospective st...
0
Return to activity following fasciotomy for chronic exertional compartment syndrome
DOD - Acute Comp Syndrome CPG
Diagnosis of chronic exertional compartment syndrome (CECS) is relatively rare but has been well documented in athletes. There are, however, few reports regarding return to athletic activity after surgery among elite-level athletes. We hypothesized that a majority of elite-level athletes would successfully return to th...
0
Functional outcome after successful internal fixation versus salvage arthroplasty of patients with a femoral neck fracture
Hip Fx in the Elderly 2019
OBJECTIVES: To determine patient independency, health-related and disease-specific quality of life (QOL), gait pattern, and muscle strength in patients after salvage arthroplasty for failed internal fixation of a femoral neck fracture. DESIGN: Secondary cohort study to a randomized controlled trial. SETTING: Multicente...
0
Comparison of polyethylene wear with femoral heads of 22 mm and 32 mm. A prospective, randomised study
Management of Hip Fractures in the Elderly
In this prospective, randomised study, we have compared the wear rate of cemented, acetabular polyethylene cups articulating with either a 22 mm or a 32 mm cobalt-chromium head. We evaluated 89 patients who had a total of 484 radiographs. The mean follow-up period was 71.4 months (SD 29.1). All the radiographs were dig...
0
Ethnic microaggressions, traumatic stress symptoms, and Latino depression: A moderated mediational model
DoD PRF (Psychosocial RF)
Although ethnic microaggressions have received increased empirical attention in recent years, there remains a paucity of research regarding how these subtle covert forms of discrimination contribute to Latino mental health. The present study examined the role of traumatic stress symptoms underlying the relationship bet...
0
The role of regenerative medicine in the treatment of sports injuries
OAK 3 - Non-arthroplasty tx of OAK
Traditional treatment of sports injuries includes use of the PRICE principle (Protection, Rest, Ice, Compression, Elevation), nonsteroidal anti-inflammatories, physical therapy modalities, and corticosteroid injections. Recent evidence has raised concerns over this traditional treatment approach regarding the use of an...
1
Comparative effectiveness of glucosamine, chondroitin, acetaminophen or celecoxib for the treatment of knee and/or hip osteoarthritis: a network meta-analysis
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVES: To compare the efficacies of oral glucosamine, chondroitin, the combination of glucosamine and chondroitin, acetaminophen and celecoxib on the treatment of knee and/or hip osteoarthritis. METHODS: We searched electronic databases including PubMed, Embase, and Cochrane Library and the reference lists of rele...
0
Prospective, double blind, randomized, controlled trial of simvastatin in human fracture healing
Distal Radius Fractures
Although statins are widely prescribed as cholesterol-lowering drugs, a number of studies suggest that these compounds may have anabolic effects on bone. Our aim was to assess whether simvastatin affects the rate of fracture healing in humans. A prospective, double-blind, randomized controlled trial was performed. Indi...
0
Significance of laser treatment in arthroscopic therapy of degenerative gonarthritis. A prospective, randomised clinical study and experimental research
AMP (Acute Meniscal Pathology)
To ascertain the efficiency of different techniques of arthroscopic therapy for gonarthritis and establish the relevance of the extent of chondromalacia, clinical and experimental studies were performed. In principle, the process of chondromalacia determines the course of the disease. Treatment of additional meniscus l...
1
Use of glucosamine and chondroitin in persons with osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
Glucosamine and chondroitin are members of a group of dietary supplements often termed "complementary agents," "disease-modifying agents," or "disease-modifying osteoarthritis drugs" (DMOADs). They are among the best-selling dietary supplements in the United States. DMOADs are thought to act by affecting cytokine-media...
0
Discrimination of hip fracture in elderly women by a new quantitative ultrasound bone measurement: comparison with dual energy X-ray absorptiometry [abstract]
Management of Hip Fractures in the Elderly
13th International Bone Densitometry Workshop. 4-8 October 1998. Lake Lawn Resort, Delavan, Wisconsin, USA
1
Effect of Extended Prophylactic Antibiotic Duration in the Treatment of Open Fracture Wounds Differs by Level of Contamination
DoD SSI (Surgical Site Infections)
OBJECTIVE: To determine the association between prophylactic antibiotic duration after the definitive wound closure of an open fracture and deep surgical site infection (SSI). DESIGN: Retrospective cohort study. SETTING: 41 clinical sites in the United States, Canada, Australia, Norway, and India. PARTICIPANTS: Patient...
0
A Study to Evaluate the Safety and Effectiveness of Different Doses of Chrysalin in Adults Who Have a Broken Wrist
Distal Radius Fractures
There is a medical need for a product that is safe and can accelerate the rate of bone healing, leading to a reduction in immobilization time. Chrysalin, also known as TP508, is a synthetic peptide (protein) that is an exact copy of part of the human protein thrombin, which is a protein that occurs naturally in the bod...
0
Bladder function in spinal anaesthesia
Surgical Management of Osteoarthritis of the Knee CPG
Spinal anaesthesia with bupivacaine (22.5 mg) or with a glucose-containing solution of bupivacaine (20 mg) or tetracaine (15 mg) was given to 21 patients allocated randomly to these three groups. A urodynamic study was performed by CO2 cystometry. It consisted of recording of first sensation of bladder filling, sensati...
0
Surgical treatment of undisplaced femoral neck fractures in the elderly
Management of Hip Fractures in the Elderly
The study was a retrospective evaluation and comparison. Eighty-four elderly patients (> 60 years) with undisplaced intracapsular femoral neck fractures were treated with osteosynthesis with either dynamic hip screws (DHS) or multiple cannulated screws (MCS). The Singh index was used to evaluate bone quality. All patie...
0
Analysis of displacement and deformation of the medial meniscus with a horizontal tear using a three-dimensional computer model
AMP (Acute Meniscal Pathology)
PURPOSE: The displacement and deformation of the knee meniscus significantly affect its roles; however, little is known about the displacement and deformation patterns of a torn medial meniscus. The objective of this study was to evaluate quantitatively the patterns of displacement and deformation in horizontally torn ...
1
The second lumbrical-interosseous latency comparison in carpal tunnel syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Carpal tunnel syndrome (CTS) is the most common nerve entrapment syndrome. Electromyogram (EMG) is beneficial in supporting the diagnosis of CTS. We compared standard nerve conduction studies of EMG with median and ulnar motor nerve conduction studies from recordings of second lumbrical and interosseal muscles in suppo...
0
An update on the evaluation and treatment of syndesmotic injuries
Pediatric Supracondylar Humerus Fracture 2020 Review
INTRODUCTION: Injuries to the distal tibiofibular syndesmosis are frequent and continue to generate controversy. METHODS: The majority of purely ligamentous injuries ("high ankle sprains") is not sassociated with a latent or frank tibiofibular diastasis and may be treated with an extended protocol of physical therapy. ...
0
Effect of adductor canal block on pain in patients with severe pain after total knee arthroplasty: A randomized study with individual patient analysis
AAHKS (8) Anesthetic Infiltration
Background Total knee arthroplasty (TKA) is associated with varying degrees of pain. A considerable proportion (25-40%) of patients experience severe pain, despite a comprehensive multimodal analgesic regimen. We hypothesized that adductor canal block (ACB) would reduce pain in this patient category compared with place...
0
Open reduction and internal fixation of displaced proximal humerus fractures with AO stainless steel T-Plate
DoD SSI (Surgical Site Infections)
Background: Proximal humeral fractures are considered the last unsolved fractures in orthopaedics. The treatment is controversial and various operative modalities have been reported in the literature. The aim of the present study was to evaluate functional outcome and complication rate after open reduction and internal...
0
Unicompartmental knee replacement with ZUK prosthesis: Mid-term results
Surgical Management of Osteoarthritis of the Knee CPG
Differently from the historic clinical reports, all recent series in literature show excellent or good results at long-term follow-up after unicompartmental knee replacement. This difference is mainly the consequence of improved surgical technique and materials, and the new prosthetic designs and ancillary. Aim of our ...
0
Recurrent falls and mortality in Parkinsonâ??s disease: A prospective twoâ?쳌year followâ?쳌up study
DoD PRF (Psychosocial RF)
Objectives: To evaluate the risk factors for recurrent falling and mortality in Parkinsonâ??s disease (PD) in a prospective study design. Materials and methods: One hundred and twenty-five PD patients were included in the study. Baseline medical data were collected, and patients were clinically tested for mobility and ...
0
Clinical Outcomes of Osteochondral Allograft Transplantation for Secondary Treatment of Osteochondritis Dissecans of the Knee in Skeletally Mature Patients
AMP (Acute Meniscal Pathology)
Purpose: To report clinical outcomes of osteochondral allograft transplantation (OCA) for skeletally mature patients with osteochondritis dissecans (OCD) lesions of the knee in whom prior surgical intervention has failed, and to describe return-to-sport (RTS) rates and any predictive demographic or preoperative variabl...
0
Geographic Variation in Use of Ambulance Transport to the Emergency Department
Hip Fx in the Elderly 2019
Study objective Evidence on variability in emergency medical services use is limited. We obtain national evidence on geographic variation in the use of ambulance transport to the emergency department (ED) among Medicare enrollees and assess the role of health status, socioeconomic status, and provider availability. Met...
1
The incidence and risk factors for lower limb skin graft failure
Reconstruction After Skin Cancer
Lower limb skin grafts are thought to have higher failure rates than skin grafts in other sites of the body. Currently, there is a paucity of literature on specific factors associated with lower limb skin graft failure. We present a series of 70 lower limb skin grafts in 50 patients with outcomes at 6 weeks. One-third ...
0
Factors affecting appearance patterns of hip-flexion contractures and their effects on postural and gait abnormalities
Management of Hip Fractures in the Elderly
Hip flexion contractures accompanying various orthopedic and neurologic conditions not only limits the physical activities of the patients but also distorts their postures and gait patterns. The purposes of this study were to characterize the appearance patterns of flexion contracture at the hip joints and to elucidate...
0
Influence of controlled hypotension versus normotension on amount of blood loss during breast reduction
Reduction Mammoplasty for Female Breast Hypertrophy
Controlled hypotension employed during surgical procedures results in a beneficial reduction in blood loss during the operation. Breast reduction is a common cosmetic surgical procedure. Yet, in the Netherlands, controlled hypotension is not standard during breast reduction procedures, and in fact is only occasionally ...
0
Bone density and microarchitecture in endogenous hypercortisolism
Distal Radius Fractures
OBJECTIVE: Osteoporosis is a serious and underestimated complication of endogenous hypercortisolism that results in an increased risk of fractures, even in patients with normal or slightly decreased bone mineral density (BMD). Alterations in bone microarchitecture, a very important component of bone quality, may explai...
1
Osteopathic manipulative treatment improves function and relieves pain in knee osteoarthritis: A single-blind, randomized-controlled trial
OAK 3 - Non-arthroplasty tx of OAK
Objectives: In this study, we aimed to compare the efficacy of osteopathic manipulative treatment (OMT) to exercise treatment in the knee osteoarthritis (OA). Patients and methods: A total of 100 patients (9 males, 76 females; mean age 54.8±8.5 years; range, 40 to 70 years) with Stage II-III bilateral knee OA enrolled...
0
Optimal patellar alignment with minimally invasive approaches in total knee arthroplasty after a minimum five year follow-up
PJI DX Updated Search
Purpose: Patellofemoral syndrome is still a common complication after total knee arthroplasty (TKA). However, the effects of specific surgical approaches on patellar tracking and alignment remain incompletely understood. In this study, we compared patellar alignment in patients who underwent TKA via three different tec...
0
OARSI/OMERACT initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis. An OMERACT 10 Special Interest Group
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: To define pain and physical function cutpoints that would, coupled with structural severity, define a surrogate measure of "need for joint replacement surgery," for use as an outcome measure for potential structure-modifying interventions for osteoarthritis (OA). METHODS: New scores were developed for pain a...
0
Deliberate Self-Harm in Psychiatric Outpatients Aged 14-35 Years in Singapore
DoD PRF (Psychosocial RF)
INTRODUCTION: The main aim of the study was to identify the prevalence of deliberate self-harm (DSH) in a sample of youth outpatients attending the state psychiatric hospital in Singapore and to identify the sociodemographic and psychological/clinical risk factors associated with DSH. The secondary aim of the study was...
0
Characterization of knee meniscal pathology: correlation of gross, histologic, biochemical, molecular, and radiographic measures of disease
AMP (Acute Meniscal Pathology)
Meniscal pathology is an extremely prevalent problem, which inevitably leads to osteoarthritis and associated pain, swelling, and disability. Relatively little data are available regarding the molecular, biochemical, and histologic aspects of meniscal disease. This study characterizes meniscal pathology in the presence...
0
Successful antibiotic treatment of Helicobacter pylori negative gastric mucosa associated lymphoid tissue lymphomas
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Background and aims: The role of antibiotic treatment in early stage gastric mucosa associated lymphoid tissue (MALT) lymphoma not associated with Helicobacter pylori infection has not been investigated. Patients and methods: Six patients with localised gastric MALT lymphoma underwent antibiotic treatment with clarithr...
0
Pain at Multiple Sites Is Associated With Prevalent and Incident Fractures in Older Adults
Hip Fx in the Elderly 2019
Musculoskeletal pain is common and typically occurs at multiple sites. Pain has been shown to be associated with falls risk; however, whether an increased risk for falls associated with multisite pain (MSP) translates into an increased risk of fractures has not been investigated. This study aimed to examine the associa...
0
Reversal of skeletal effects of endocrine treatments in the Intergroup Exemestane Study
Hip Fx Time to Surgery
The adjuvant use of aromatase inhibitors in breast cancer is associated with adverse effects on bone health. We previously reported a decline in bone mineral density (BMD) following the switch from tamoxifen to exemestane in the Intergroup Exemestane Study (IES). Here we report effects of endocrine treatment withdrawal...
0
Eighteen-year follow-up after rotationplasty for a grade IIIC open fracture of the distal femur
DoD LSA (Limb Salvage vs Amputation)
We report the 18-year follow-up of a patient who underwent rotationplasty for severe bone loss and infection after an grade IIIC open fracture of the distal femur. The patient is now 49 years old and fully satisfied with his life. During the follow-up period, he has never had significant physical or psychological probl...
0
The oral health of children considered very high risk for infective endocarditis
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
BACKGROUND: Children with previous experience of infective endocarditis or with prosthetic heart valve are considered at very high risk for infective endocarditis. AIM: The aim of this study was to compare the dental health of a group of these children with a group of healthy controls and to determine parental awarenes...
0
Additional information from quantitative 24-hour 99mTc-MDP bone scintigraphy in patients with prostatic carcinoma
MSTS 2018 - Femur Mets and MM
Quantitative bone scintigraphy was performed at 4 and 24 h after injection of 99mTc-MDP. The lower thoracic and all the lumbar vertebrae were recorded in 37 patients with prostatic carcinoma before orchiectomy as well as two weeks, two and six months postoperatively. Fourteen patients had normal bone scintigrams. By me...
1
Venous thromboembolism in abdominoplasty: a comprehensive approach to lower procedural risk
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Venous thromboembolism (VTE) is a serious and potentially life-threatening surgical complication. However, there is little consensus regarding appropriate VTE prophylaxis for plastic surgery patients. Risk factors as they apply to plastic surgery patients are unclear, and recent recommendations for chemopro...
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Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast
Reduction Mammoplasty for Female Breast Hypertrophy
The developmental relationships between the different mammary epithelial cell lineages in the human mammary gland are not well defined. To characterize human breast epithelial cells (HBEC) with progenitor activity, we used flow cytometry and single cell sorting to analyze the distribution of cellular phenotypes in prim...
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A cost-utility analysis comparing large volume displacement oncoplastic surgery to mastectomy with single stage implant reconstruction in the treatment of breast cancer
Reduction Mammoplasty for Female Breast Hypertrophy
BACKGROUND: For larger cancers in moderate to large breast sized women, breast surgical cancer treatment may include large volume displacement oncoplastic surgery (LVOS) or mastectomy with single stage implant reconstruction (SSIR). Often in the case of LVOS, reduction mammaplasty designs are used in the oncoplastic re...
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Global experience of orthopaedic trauma surgeons facing COVID-19: a survey highlighting the global orthopaedic response
Coronavirus Disease 2019 (COVID-19)
BACKGROUND: The COVID-19 (SARS-CoV-2) pandemic has significantly affected all aspects of healthcare, including orthopaedics. Due to the unique challenges presented by COVID-19 as well as the distinct timeframes that it will surge in different geographies, much can be learned from the experiences of orthopaedic professi...
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Zoledronic acid: an advance in tumour bone disease therapy and a new hope for osteoporosis
MSTS 2018 - Femur Mets and MM
The two main therapeutic applications of bisphosphonates are tumour bone disease and osteoporosis. They constitute the standard treatment for cancer hypercalcaemia, and placebo-controlled trials have shown that the prolonged administration of bisphosphonates, such as pamidronate or clodronate, can reduce the frequency ...
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Utility of early screening magnetic resonance imaging for extensive hip osteonecrosis in pediatric patients treated with glucocorticoids
AAHKS (2) Corticosteroids
PURPOSE: Hip osteonecrosis frequently complicates treatment with glucocorticoids. When extensive (affecting >= 30% of the epiphyseal surface), 80% of joints collapse within 2 years, so interventions are needed to prevent this outcome. PATIENTS AND METHODS: This prospective cohort magnetic resonance imaging (MRI) screen...
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The preoperative prevalence and postoperative incidence of thromboembolism in patients with hip fractures treated with dextran prophylaxis
Management of Hip Fractures in the Elderly
A prospective preoperative and postoperative venographic study of hip fracture patients has documented a significant preoperative prevalence and postoperative incidence of thromboembolic disease. A statistically higher incidence of deep-venous thrombosis is observed in patients with femoral neck fractures compared to p...
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Use of an alumina-on-alumina bearing system in total hip arthroplasty for osteonecrosis of the hip
Management of Hip Fractures in the Elderly
BACKGROUND: The results of total hip arthroplasty in patients with osteonecrosis of the femoral head are not always optimal. The use of alumina-on-alumina interfaces in young and active patients may decrease wear and lower the rate of aseptic loosening of the implant and appears to be an attractive alternative to the u...
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Severe ocular injuries from orthodontic headgear
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Dislocation of extraoral orthodontic tractional devices (headgear) resulted in penetrating ocular injuries in three eyes of two patients. An endophthalmitis caused by mixed flora developed in each injured eye. Despite medical and surgical therapy, only one eye retained useful vision two years following injury. All wear...
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Reliability of performance-based measures in people awaiting joint replacement surgery of the hip or knee
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND AND PURPOSE: Understanding the reliability of selected measurement tools is a prerequisite to understanding the effects of clinical interventions. The aim of this investigation was to determine the reliability of the 50-Foot Timed Walk (50 FTW) and 30-second Chair Stand Test (30 CST) in subjects awaiting joi...
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Changes in oxygen saturation in the 72 hours after hip surgery: the effect of oxygen therapy
Management of Hip Fractures in the Elderly
The aim of this study was to investigate changes in oxygen saturation (SpO2) occurring during the three days following hip surgery in patients in this hospital and to determine to what extent SpO2 might be improved by oxygen therapy for 24 or 72 hours. Eighty-three patients (aged 43-96 years) scheduled for elective tot...
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Shoulder arthroplasty for advanced glenohumeral arthritis after anterior instability repair
Glenohumeral Joint OA
We retrospectively reviewed 19 patients (19 shoulders) in whom advanced glenohumeral arthritis developed after anterior instability repair. The anterior instability repairs included 4 Bristow, 4 Putti-Platt (2 in combination with other procedures), 4 Magnuson-Stack, 2 Bankart, and 5 other anterior capsulorrhaphies. Sev...
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Workplace surveillance for carpal tunnel syndrome: A comparison of methods
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
A variety of screening procedures for carpal tunnel syndrome (CTS) were applied among workers in a manufacturing plant, and results were compared. The test procedures included a symptom survey, physical examination, limited electrodiagnostic testing at the wrists, quantitative vibratory threshold testing, 2-point discr...
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Comparison between EMG-Biofeedback controlled exercises and conventional exercises on knee osteoarthritis treatment, a clinical trial
OAK 3 - Non-arthroplasty tx of OAK
INTERVENTION: Control group; 1�Conventional knee osteoarthritis exercises training to patients include; Strengthening exercises of Quadriceps muscles, Strengthening of Hip adductors, Closed Kinematic Chain exercises, Stretching exercises for Hamstring muscle and Properioception training by physical therapist and reco...
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Concomitant orthopedic and vascular injuries as predictors for limb loss in blunt lower extremity trauma
DoD LSA (Limb Salvage vs Amputation)
Lower extremity trauma with concomitant orthopedic and vascular injury is associated with a high degree of limb loss. Despite successful arterial repair, many patients will ultimately require amputations. The effect of associated orthopedic injuries on limb loss in patients with lower extremity arterial injuries is inv...
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Diagnostic alterations for post-traumatic stress disorder: examining data from the National Comorbidity Survey Replication and National Survey of Adolescents
DoD PRF (Psychosocial RF)
BACKGROUND: Two alternative models of post-traumatic stress disorder (PTSD) appear to represent the disorder's latent structure better than the traditional Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) three-factor PTSD model. The present study examines the impact of using these structural...
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Biomechanical analysis of supracondylar humerus fracture pinning for slightly malreduced fractures
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
BACKGROUND: The most common position of malreduced type III supracondylar humerus (SCH) fractures is internal rotation and medial collapse of the distal fragment. The purpose of this study was to determine the effect of SCH fracture rotational deformity on stability with various pin configurations. Specifically, is the...
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Hannover Fracture Scale '98 - Re-evaluation and new perspectives of an established extremity salvage score
DoD LSA (Limb Salvage vs Amputation)
Objective: as the treatment of open fractures has improved over the years, the prognosis of open fractures has also changed. Thus, a re-evaluation of the Hannover Fracture Score (HFS), first introduced in 1983, has become necessary. Design: retrospectively all parameters of the HFS were evaluated in 182 open fractures ...
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Initial experience with the Forte plate for dorsally displaced distal radius fractures
Management of Hip Fractures in the Elderly
Open reduction and plate osteosynthesis is occasionally indicated for dorsally displaced distal radius fractures. We reviewed our medium term results with the Forte plate, one of the recently introduced purpose-made implants.Twenty-five patients operated on during the first year were reviewed 19 (12-24) months after su...
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Curettage and cryosurgery for low-grade cartilage tumors is associated with low recurrence and high function
MSTS 2018 - Femur Mets and MM
Background: Chondrosarcomas of bone traditionally have been treated by wide or radical excision, procedures that may result in considerable lifelong disability. Grade 1 chondrosarcomas have little or no metastatic potential and are often difficult to distinguish from painful benign enchondromas. Curettage with adjuvant...
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The influence of patellofemoral degenerative changes on the outcome of unicompartmental knee replacement (UKA)
Surgical Management of Osteoarthritis of the Knee CPG
Aim: Patellofemoral (PF) joint degeneration is widely considered to be a contraindication to medial compartment UKA. We examined the validity of this preconception Methods: information gathered prospectively on 147 consecutive patients who underwent the Repicci II(plus or minus)UKA for medial compartment osteoarthritis...