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Diffusion tensor imaging of articular cartilage using a navigated radial imaging spin-echo diffusion (RAISED) sequence
OAK 3 - Non-arthroplasty tx of OAK
Objective: To validate a radial imaging spin-echo diffusion tensor (RAISED) sequence for high-resolution diffusion tensor imaging (DTI) of articular cartilage at 3 T. Methods: The RAISED sequence implementation is described, including the used non-linear motion correction algorithm. The robustness to eddy currents was...
0
Intrathecal ropivacaine and clonidine for ambulatory knee arthroscopy: a dose-response study
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: The aim of this study was to evaluate the association of a small dose of intrathecal ropivacaine with small doses of intrathecal clonidine for ambulatory surgery. METHODS: One hundred twenty patients, classified as American Society of Anesthesiologists physical status I and scheduled for knee arthroscopy, w...
0
A Comparison of Single Shot Adductor Canal Block Versus Femoral Nerve Catheter for Total Knee Arthroplasty
AAHKS (8) Anesthetic Infiltration
The aim of this study was to compare perioperative analgesia provided by single-injection adductor canal block (ACB) to continuous femoral nerve catheter (FNC) when used in a multimodal pain protocol for total knee arthroplasty (TKA). A retrospective cohort study compared outcome data for 148 patients receiving a singl...
1
Dental X-ray status of patients admitted for total hip replacement
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
The dental status of 50 patients undergoing total hip replacement (THR) was evaluated. Fourteen of the patients had no teeth. The teeth of the remaining 36 patients were in poor condition. Decay was severe in 12. Periapical infectious foci were evident in the panoramic radiographs of 24 patients. Nearly all of the 36 p...
0
Monocyte chemotactic protein-1 inhibits chondrogenesis of synovial mesenchymal progenitor cells: an in vitro study
OAK 3 - Non-arthroplasty tx of OAK
Osteoarthritis (OA) is a multifactorial, often progressive, painful disease. OA often progresses with an apparent irreversible loss of articular cartilage, exposing underlying bone, resulting in pain and loss of mobility. This cartilage loss is thought to be permanent due to ineffective repair and apparent lack of stem...
0
Brain activity measurement at performing motivative exercise and passive exercise by Functional Near-Infrared Spectroscopy (Outpatient rehabilitation facilities)
OAK 3 - Non-arthroplasty tx of OAK
INTERVENTION: The Motivative exercise and Passive exercise to legs/leg for 30 seconds respectively. It carried out on December 8�10, 2009 CONDITION: Cerebrovascular disease, Cerebral infarction, Cerebral contusion, Cerebral hemorrhage, Aftereffect of cerebral hemorrhage, Basilar artery occlusion, Cerebral arterioscle...
0
Aseptic Revision and Reoperation Risks After Meniscectomy at the Time of Anterior Cruciate Ligament Reconstruction
AMP (Acute Meniscal Pathology)
BACKGROUND: An intact meniscus is considered a secondary stabilizer of the knee after anterior cruciate ligament reconstruction (ACLR). While loss of the meniscus can increase forces on the anterior cruciate ligament graft after reconstruction, it is unclear whether this increased loading affects the success of the gra...
1
The Effect of Multifactorial Intervention Programs on Health Behavior and Symptom Control Among Community-Dwelling Overweight Older Adults With Knee Osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: Osteoarthritis of the knee (OA knee), especially in older adults, is the most common chronic illness and a major public health problem. Overweight older adults are at a high risk of developing OA knee and suffering from OA knee symptoms, which cause older adults to become disabled and have functional limita...
1
Activity, air boots, and aspirin as thromboembolism prophylaxis in knee arthroplasty. A multiple regimen approach
Surgical Management of Osteoarthritis of the Knee CPG
In this prospective study 90 patients underwent 100 total knee replacements. Each patient walked and practiced rehabilitation exercises one day preoperatively and the morning of surgery. The contralateral calf was intermittently pumped during surgery followed by bilateral pulsatile calf compression postoperatively. Asp...
0
Phase II study of glucosamine with chondroitin on aromatase inhibitor-associated joint symptoms in women with breast cancer
OAK 3 - Non-arthroplasty tx of OAK
PURPOSE: Many women with hormone receptor-positive breast cancer discontinue effective aromatase inhibitor (AI) treatment due to joint symptoms. METHODS: We conducted a single-arm, open-label, phase II study evaluating glucosamine-sulfate (1,500 mg/day) + chondroitin-sulfate (1,200 mg/day) for 24 weeks to treat joint p...
0
Maintaining Levels of Lower Extremity Amputations
DoD LSA (Limb Salvage vs Amputation)
Patients who have undergone a lower extremity amputation may develop an unstable soft tissue envelope of the amputation stump. This envelope may result in pain that prohibits prosthetic use or may become chronically infected. Providing stable soft tissue coverage at the amputation site may provide relief from pain and ...
0
Correction of Femoral Valgus Deformity
AMP (Acute Meniscal Pathology)
In the past two decades, the insights in the causes and development of valgus leg deformities as well as the options for treatment with corrective osteotomies have dramatically changed. New definitions for deformity analysis and planning for corrections have better defined the patients suitable for femoral valgus defor...
0
Cryopreservation of whole adipose tissue for future use in regenerative medicine
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Human adipose tissue (AT) is an ideal stem cell source for autologous cell-based therapies. The preferred setting for tissue engineering and regenerative medicine applications is the availability of clinically acceptable off-the-shelf cells and cell products. As AT is not always available for use, cryoprese...
0
Concomitant hip and upper extremity fracture in elderly patients: Prevalence and clinical implications
Distal Radius Fractures
BACKGROUND: Hip fracture and upper extremity fracture are most important age-related fracture. However, there have been few reports about the analysis of prevalence or risk factors with concomitant hip and upper extremity fractures. This study aimed to describe the prevalence and clinical implications of the concomitan...
0
Treatment of distal metaphyseal tibia fractures using an external fixator in children
DoD SSI (Surgical Site Infections)
INTRODUCTION: Current treatment of pediatric distal metaphyseal tibial/fibular fractures is challenging due to poor skin and soft tissue coverage and limited blood supply to the distal tibia area in children. It remains unknown whether the SK combined external fixator (made by Double Medical Technology Inc., China) is ...
0
Total knee arthroplasty for steroid-induced osteonecrosis
AAHKS (2) Corticosteroids
There have been only a few reports that evaluate the outcome of total knee arthroplasty in patients with steroid-induced osteonecrosis of the knee. We retrospectively reviewed 31 total knee arthroplasties in 24 patients with confirmed steroid-induced osteonecrosis of the knee. The average follow-up was 64 months. Of su...
0
Circulating neuron-specific enolase in medullary thyroid cancer
MSTS 2018 - Femur Mets and MM
The utility of determining circulating neuron-specific enolase (NSE) in medullary thyroid carcinoma was assessed in 25 patients followed up for a mean period of 45.6 months. In 5 patients tested before any treatment serum NSE concentrations were in the normal range. After total thyroidectomy abnormally high serum NSE c...
0
Charlson co-morbidity index and albumin significantly associated with fracture risk in peritoneal dialysis patients
DoD SSI (Surgical Site Infections)
Published literature on fracture in dialysis patients seldom addressed the effect of co-morbidity and malnutrition. In this study, we reported the incidence and risk factors for fracture in peritoneal dialysis patients. Peritoneal dialysis patients who had fractures between 2006 and 2011 were recruited. Demographic dat...
0
Changes in alveolar bone height and width following post-extraction ridge augmentation using a fixed bioabsorbable membrane and demineralized freeze-dried bone osteoinductive graft
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Background: It has been shown that the amount of healed bone following guided bone regeneration (GBR) with demineralized freeze-dried bone allograft (DFDBA) and a bioabsorbable membrane is significantly less than the initial quantity. A study was designed to determine if the amount of GBR would be affected by using an ...
0
Falls in the elderly
Management of Hip Fractures in the Elderly
Falls are the leading cause of injury-related visits to emergency departments in the United States and the primary etiology of accidental deaths in persons over the age of 65 years. The mortality rate for falls increases dramatically with age in both sexes and in all racial and ethnic groups, with falls accounting for ...
0
Two cannulated hip screws for femoral neck fractures: treatment of choice or asking for trouble?
Management of Hip Fractures in the Elderly
INTRODUCTION: Undisplaced intracapsular fractures are predominantly treated with a minimally invasive fixation technique, whereas the standard treatment for displaced intracapsular fractures is still a subject of discussion. The purpose of this study was to identify the determinants influencing the outcome of intracaps...
0
Volar locking plating treatment results in fragmented intraarticular distal radius fractures
Distal Radius Fractures
Volar locking plating treatment results in fragmented intra-articular distal radius fractures in adults. Twenty-five patients (14 men, 11 women; mean age, 44.32±12.12 years) who were treated with volar locking plates due to distal radius fractures were prospectively studied. Among the fractures, 44% were C2 and 56% we...
0
Sedative-hypnotic drugs and the risk of hip fracture
Management of Hip Fractures in the Elderly
A retrospective cohort study was conducted in individuals 65 years of age and older using Medicaid-reimbursed claims to assess the risk of hip fracture in users of two sedative-hypnotic drugs, triazolam and temazepam. Using the triazolam cohort as the referent group, the rate ratio was 0.92 (95% confidence interval, 0....
0
Is prophylactic fixation a cost-effective method to prevent a future contralateral fragility hip fracture?
PJI DX Updated Search
OBJECTIVE: : A previous hip fracture more than doubles the risk of a contralateral hip fracture. Pharmacologic and environmental interventions to prevent hip fracture have documented poor compliance. The purpose of this study was to examine the cost-effectiveness of prophylactic fixation of the uninjured hip to prevent...
0
Adaptation of human skeletal muscle to training and anabolic steroids
Glenohumeral Joint OA
Understanding the cellular and molecular adaptations of skeletal muscle in response to strength training is important to provide frameworks to improve performance of elite and recreational athletes as well as the health and quality of life of the general population with or without chronic diseases. This work was mainly...
1
Open distal tibial shaft fractures: a retrospective comparison of medial plate versus nail fixation
DoD SSI (Surgical Site Infections)
PURPOSE: Studies comparing open reduction internal fixation (ORIF) vs. intramedullary nailing (IMN) for distal tibia shaft fractures focus upon closed injuries containing small patient series with open fractures. As such, complication rates for open fractures are unknown. To characterize complications associated with O...
1
Exercise combined with continuous passive motion or slider board therapy compared with exercise only: a randomized controlled trial of patients following total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND AND PURPOSE: The primary purpose of this randomized controlled trial was to determine which method of mobilization - (1) standardized exercises (SE) and continuous passive motion (CPM), (2) SE and slider board (SB) therapy, using an inexpensive, nontechnical device that requires minimal knee active range of ...
0
Morbid obesity and excessive hospital resource consumption for unilateral primary hip and knee arthroplasty
PJI DX Updated Search
Two objectives of this study were (i) to estimate the number of primary total hip arthroplasty (THA) or total knee arthroplasty (TKA) performed on morbidly obese people in the United States, and (ii) to estimate the economic impact of morbid obesity on hospital resource use. In 2006, approximately 2.9% (6713 cases) of ...
0
Five-year comparative study of highly cross-linked (crossfire) and traditional polyethylene
Management of Hip Fractures in the Elderly
The purpose of this study was to compare the linear penetration rates of a highly cross-linked ultra-high-molecular-weight polyethylene to traditional polyethylene. Twenty-seven highly cross-linked components were matched to 27 traditional polyethylene components with respect to age, sex, body mass index, and activity ...
0
Plasma cell leukemia: A highly aggressive monoclonal gammopathy with a very poor prognosis
MSTS 2018 - Femur Mets and MM
Plasma cell leukemia (PCL) is an aggressive variant of multiple myeloma and is characterized by the presence of >20% and/or an absolute number of greater 2 Ã? 10(9)/L plasma cells circulating in the peripheral blood. PCL represents approximately 2-4% of all MM diagnosis and exists in two forms: primary PCL (PPCL, 60% o...
0
Periprosthetic joint infection: treatment options
PJI DX Updated Search
Periprosthetic joint infection has become the most common cause of failure following total knee arthroplasty. Over the past 4 decades, treatment of this disease has evolved with technological innovations and pathogen profiling. The appropriate treatment selection is dependent on patient immune system quality, timing of...
0
Cannulated screw fixation for femoral neck fractures: A 5-year experience in a single institution
Hip Fx in the Elderly 2019
Cannulated screw fixation is a widely accepted surgical method for management of fractures of the neck of femur especially in patients with poor premorbid conditions, minimally displaced fractures and those from a younger age group. A five year retrospective study was carried out in 53 consecutive patients between 2006...
0
Low back pain after unstable extracapsular hip fractures: randomized control trial on a specific training
Management of Hip Fractures in the Elderly
AIM: This study compares the efficacy of a walking recovery rehabilitation program with or without specific back exercises in patients affected by unstable extracapsular hip fractures and secondary back pain. Further, it reports data and images about analysed tomographic changes of the psoas muscle ipsilateral to fract...
0
Resilience linked to personality dimensions, alexithymia and affective symptoms in motor functional neurological disorders
DoD PRF (Psychosocial RF)
OBJECTIVE: Reduced resilience, a construct associated with maladaptive stress coping and a predisposing vulnerability for Functional Neurological Disorders (FND), has been under-studied compared to other neuropsychiatric factors in FND. This prospective case-control study investigated self-reported resilience in patien...
0
Pressure algometry is an excellent tool to measure knee pain relief after a closing-wedge high tibial osteotomy
OAK 3 - Non-arthroplasty tx of OAK
Purpose: The aim of this study was to assess the utility of pressure algometry (PA) to measure pain relief in the medial part of the knee after a closing-wedge high tibial osteotomy (CWHTO). Methods: Prospective study including 44 CWHTO. Pain relief was evaluated with the visual analogue scale (VAS) and PA, a radiologi...
0
Increased bone resorption and decreased bone formation in Chinese patients with hip fracture
Management of Hip Fractures in the Elderly
Biochemical markers of bone formation (bone-specific alkaline phosphatase and osteocalcin) and bone resorption (hydroxyproline excretion and bone isoenzyme of acid phosphatase) were measured in 30 patients (15 M and 15 F) with hip fracture and 30 healthy subjects matched for age and sex. Bone isoenzyme of tartrate-resi...
1
Carpal tunnel syndrome: evaluation of a new method of assessing median nerve conduction at the wrist
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
OBJECTIVE: To compare median nerve conduction velocity measured using a new, portable electroneurometer with measurements made using conventional hospital nerve conduction apparatus. METHODS: Twenty five patients were studied who were consecutively referred to a hospital neurophysiology department with a clinical diagn...
0
Influence of magnetic resonance imaging on indications for arthroscopy of the knee
AMP (Acute Meniscal Pathology)
In a prospective study, magnetic resonance imaging was performed before arthroscopy for all patients (n = 121) with a meniscal tear (n = 125). Criteria of the study were stable cruciate and collateral ligaments, absence of pathologic radiographic findings, and absence of prior surgical interventions of the involved kne...
0
Radial head replacement with a bipolar system: an average 10-year follow-up
Glenohumeral Joint OA
BACKGROUND: We report the long-term results of a cohort of patients after radial head replacement with a bipolar design and a smooth cementless stem at a mean follow-up of 10.4 years. METHODS: Of 17 possible patients from a previous minimum 2-year follow-up study, 16 were available for review. Patients were assessed us...
0
Factors affecting revenue from the management of pelvis and acetabulum fractures
Hip Fx in the Elderly 2019
Objectives: The purpose was to define charges and reimbursement in the management of pelvis and acetabulum fractures and to identify opportunities for revenue enhancement. DESIGN: Retrospective review. SETTING: Level 1 trauma center. PATIENTS/PARTICIPANTS: Four hundred sixty-five patients with 210 pelvic ring injuries ...
0
Why is pain more common amongst people living in areas of low socio-economic status? A population-based cross-sectional study
DoD PRF (Psychosocial RF)
STUDY OBJECTIVE: To confirm a relationship between self-reported oro-facial pain and deprivation using an area-based measure of deprivation, and to investigate possible mechanisms of the association. DESIGN: A cross sectional population based survey. SETTING: General medical practice in South-East Cheshire (Borough of ...
0
The interest of the transversus abdominis plane block for postoperative analgesia during hysterectomy
Surgical Management of Osteoarthritis of the Knee CPG
Background and Goal of Study: The abdominal wall is a significant source of pain after abdominal surgery. Several methods are performed to control the pain after a total abdominal hysterectomy. The transversus abdominis plane (TAP) block is an expanding regional anesthesia technique that provides analgesia following ab...
0
OA phenotypes, rather than disease stage, drive structural progression--identification of structural progressors from 2 phase III randomized clinical studies with symptomatic knee OA
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND/PURPOSE: The aim of this study was to identify key characteristics of disease progression through investigation of the association of radiographic progression over two years with baseline Joint Space Width (JSW), Kellgren-Lawrence (KL) grade, Western Ontario and McMaster Universities Arthritis Index (WOMAC) ...
1
Cemented versus uncemented hemiarthroplasty for displaced femoral neck fractures: A randomized controlled trial with two years follow-up
Hip Fx in the Elderly 2019
OBJECTIVE: The aim of this prospective randomized trial was to compare cemented (CHA) and uncemented bipolar hemiarthroplasty (UCH) in patients with femoral neck fractures (FNF). METHODS: The study included 158 patients aged â?¥76 years who underwent bipolar HA for displaced FNF. Patients were randomized in two groups:...
0
Platelet-rich plasma: myth or reality?
PRP (Platelet-Rich Plasma)
Platelet-rich plasma (PRP) is a preparation for therapeutic purposes that is increasingly accepted for various musculoskeletal disorders, due to its theoretical potential to repair tissues with poor healing capacity. Several randomised clinical trials have investigated the capacity of PRP to repair tendons, ligaments, ...
0
Multiple myeloma, version 2.2016: Clinical practice guidelines in oncology
MSTS 2018 - Femur Mets and MM
Multiple myeloma (MM) is a malignant neoplasm of plasma cells that accumulate in bone marrow, leading to bone destruction and marrow failure. Recent statistics from the American Cancer Society indicate that the incidence of MM is increasing. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) included i...
0
(untitled)
SR for PM on OA of All Extremities
To assess the association between intermediate and patient-centered outcomes and harms with physical therapy interventions in community-dwelling adults with chronic knee pain secondary to osteoarthritis and to examine validity and minimum clinically important differences of the tools for outcome measurement. We searche...
0
Efficacy of Adrenaline in Periarticular Analgesic Injection on Postoperative Pain Control After Total Knee Arthroplasty
AAHKS (8) Anesthetic Infiltration
The patients will be divided into two groups. In group 1, the multimodal anesthetic cocktail consisted of 100 mg Levobupivacaine (0.5%, 20 mL) and 30 mg ketorolac (1 ml). In group 2, the multimodal anesthetic cocktail consisted of 100 mg Levobupivacaine (0.5%, 20 mL), 30 mg ketorolac (1 ml) and 0.6 mg 1:1000 epinephrin...
0
Conflicting trends in fall-related injury hospitalisations among older people: variations by injury type
Management of Hip Fractures in the Elderly
Despite advances in prevention, fall-related hospitalisation rates among older people are still increasing. Rates between 1998/1999 and 2008/2009 for non-facture-related injuries increased by 6.1% while fracture injuries declined by -0.4%. Varying trends in rates of different injury types makes it difficult to provide ...
0
Disease burden of fractures among patients with osteoporosis in Japan: health-related quality of life, work productivity and activity impairment, healthcare resource utilization, and economic costs
DoD PRF (Psychosocial RF)
Osteoporosis remains undertreated in Japan, and bone fractures are the most frequent complications imposing heavy burden on individuals and the community. This paper investigates the clinical and economic burden of fractures among osteoporosis patients in Japan. The Japan National Health and Wellness Survey 2012â??2014...
0
Treatment of segmental loss of the tibia by tibialisation of the fibula: a review of the literature
PJI DX Updated Search
Segmental defects of the tibia are challenging therapeutic problems for both the physician and the patient. These defects may be caused by severe trauma, infection, tumors and congenital processes. Several different techniques have been described for treatment of these defects including the Papineau technique, allograf...
1
Functional outcome and alignment in computer-assisted and conventionally operated total knee replacements: a multicentre parallel-group randomised controlled trial
Surgical Management of Osteoarthritis of the Knee CPG
We performed a randomised controlled trial comparing computer-assisted surgery (CAS) with conventional surgery (CONV) in total knee replacement (TKR). Between 2009 and 2011 a total of 192 patients with a mean age of 68 years (55 to 85) with osteoarthritis or arthritic disease of the knee were recruited from four Norweg...
0
Prognostic Discrepancy on Overall Survival Between Ambulatory and Nonambulatory Patients with Metastatic Spinal Cord Compression
MSTS 2022 - Metastatic Disease of the Humerus
Background: Contradictory results have been reported regarding the prognostic effect of ambulatory status in patients with metastatic spinal cord compression (MSCC). The aim of this study was to investigate whether ambulatory status is a significant predictor of overall survival in patients with MSCC and to distinguish...
1
The effect of flexion alignment in total hip arthroplasty with a cementless tapered-wedge femoral stem
Hip Fx in the Elderly 2019
INTRODUCTION: The influence of stem sagittal alignment on clinical outcomes is unclear in total hip arthroplasty (THA). The purpose of this study is to assess the relationship between stem sagittal alignment and clinical and radiographic outcomes using 3D-CT. MATERIALS AND METHODS: We performed 370 consecutive primary ...
0
Antibiotic prophylaxis before invasive dental procedures in patients with arthroplasties of the hip and knee
Dental Implant Infection
More than a million hip replacements are carried out each year worldwide, and the number of other artificial joints inserted is also rising, so that infections associated with arthroplasties have become more common. However, there is a paucity of literature on infections due to haematogenous seeding following dental pr...
0
IV vs. Oral Acetaminophen as a Component of Multimodal Analgesia After Total Hip Arthroplasty
AAHKS (9/10) Regional Nerve Blocks
A) Opioid use after THA. Opioid use after THA can be 90 mg (+/�79) in morphine equivalents when using epidural bupivacaine / hydromorphone and multimodal analgesia. Less than 1/3 of this was via the epidural (26/90 mg). Patients reported ORSDS composite scores of 0.58 B) IV vs oral acetaminophen. The therapeutic bloo...
0
Pre and postoperative median nerve conduction in patients with pituitary tumour
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
A study of median nerve sensory conduction at the wrist was performed in 34 patients with pituitary adenomas prior to and following surgery. In 31 patients this was done bilaterally. They included 11 patients with acromegalic features, 3 of whom had features of carpal tunnel syndrome. Six out of 11 (55%) acromegalics h...
0
Increased risk for second primary malignancies in women with breast cancer diagnosed at young age: a population-based study in Taiwan
MSTS 2022 - Metastatic Disease of the Humerus
Studies conducted in Western countries have reported excess risks for second primary malignancies after breast cancer. However, there is little documentation of ethnic differences in these excess risks. Asian women are characterized by younger age at diagnosis of breast cancer, but very few reports are available on the...
0
Bacterial chemoprophylaxis knowledge and practice among New Zealand dentists
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
OBJECTIVE: To investigate general dental practitioners' current understanding and practice of oral antibiotic prophylaxis. DESIGN: Cross-sectional survey of a random sample of New Zealand general dental practitioners (GDPs). METHODS: A postal questionnaire was sent to 700 GDPs (response rate 64.5%). RESULTS: Most pract...
0
Comparative analysis of total knee arthroplasty in two health care delivery systems
Surgical Management of Osteoarthritis of the Knee CPG
A prospective, concurrent comparison of patients undergoing total knee arthroplasty in two different health care delivery systems was carried out. All patients had osteoarthritis, and received treatment between September 1983 and September 1987 under the supervision of a single staff physician. There were 26 total knee...
1
Rest and recuperation in the UK Armed Forces
DoD PRF (Psychosocial RF)
BACKGROUND: Recent epidemiological evidence suggests that military personnel commonly remain psychologically resilient in the face of adversity they face on deployment. However, the processes that promote resilience have not been well assessed within the UK military. For many years, the UK Armed Forces have operated a ...
0
Blunt and penetrating trauma: Has anything changed?
DOD - Acute Comp Syndrome CPG
Management of abdominal trauma has changed significantly in the last decade. The next decade will also see significant change as imaging and minimally invasive surgical techniques evolve and more approaches are examined in well-designed prospective studies.
1
Grade 2C signal in the meniscus [correction of mensicus] on MR imaging of the knee
AMP (Acute Meniscal Pathology)
OBJECTIVE: The objective of our study was to evaluate the clinical significance of grade 2C meniscal [corrected] signal (an extensive triangular or wedge-shaped signal that does not reach the surface on more than one image) on MR imaging of the knee. MATERIALS AND METHODS: Review of 1106 MR imaging reports over 2 years...
0
Calcitriol does not prevent bone loss in patients with asthma receiving corticosteroid therapy: A double-blind placebo-controlled trial
Management of Hip Fractures in the Elderly
Introduction: Oral glucocorticoid therapy reduces bone mineral density (BMD) and increases fracture risk. It is uncertain whether inhaled glucocorticoids, the most commonly used long-term therapy for asthma, have a similar effect. If bone loss does occur, it is unclear whether this is preventable by calcitriol. Patient...
0
Acquisition of epithelial-mesenchymal transition phenotype in the tamoxifen-resistant breast cancer cell: a new role for G protein-coupled estrogen receptor in mediating tamoxifen resistance through cancer-associated fibroblast-derived fibronectin and beta1-integrin signaling pathway in tumor cells
MSTS 2018 - Femur Mets and MM
INTRODUCTION: Acquired tamoxifen resistance remains the major obstacle to breast cancer endocrine therapy. beta1-integrin was identified as one of the target genes of G protein-coupled estrogen receptor (GPER), a novel estrogen receptor recognized as an initiator of tamoxifen resistance. Here, we investigated the role ...
0
Multiple myeloma
MSTS 2018 - Femur Mets and MM
This manuscript is an introduction to the topic of multiple myeloma. Definition, incidence, etiology, pathogenesis and principles of diagnostics and treatment of multiple myeloma are described briefly in this work. It corresponds with Guidelines for diagnostics and treatment of the myeloma section of the Czech Hematolo...
0
Influence of enhanced recovery programme on hospital stay
Surgical Management of Osteoarthritis of the Knee CPG
Background: Popularity of Enhanced Recovery Programmes (ERP) is increasing due to improved outcome and early return to normal activity. We introduced ERP for Total Hip Replacement (THR) and Total Knee Replacement (TKR) in Norwich Hospital.The protocol included combined spinal-epidural anaesthetic with propofol sedation...
0
Longitudinal shapes of the tibia and femur are unrelated and variable
Surgical Management of Osteoarthritis of the Knee CPG
In general practice, short films of the knee are used to assess component position and define the entry point for intramedullary femoral alignment in TKAs; however, whether it is justified to use the short film commonly used in research settings and everyday practice as a substitute for the whole leg view is controvers...
0
Gene expression profiling of di-n-butyl phthalate in normal human mammary epithelial cells
Reduction Mammoplasty for Female Breast Hypertrophy
Studies show that female workers in the personal-care industry have an increased risk of developing cancer believed to be the result of increased exposure to toxic and/or carcinogenic chemicals found in cosmetics, hair dyes, and nail polish. One chemical found in multiple personal-care products, di-n-butyl phthalate (D...
0
Clodronic acid in the treatment of postmenopausal osteoporosis
Management of Hip Fractures in the Elderly
BACKGROUND: Clodronic acid, a first-generation bisphosphonate, has been successfully used in the treatment of high bone turnover states, Paget's disease and osteolytic bone metastases. However, controversies remain over its optimal dosage and method of administration in the treatment of postmenopausal osteoporosis. In ...
0
All-inside Arthroscopic Meniscal Repair Technique Using a Midbody Accessory Portal
AMP (Acute Meniscal Pathology)
Treatment of symptomatic meniscal tears continues to evolve as we improve our understanding of the biomechanical role of the meniscus and its long-term importance to the health of the knee joint. Suture repair of meniscal tears is challenging, yet the incidence of repairs among our colleagues continues to rise as we ai...
0
Subsartorial adductor canal vs femoral nerve block for analgesia after total knee replacement
AAHKS (4) Acetaminophen
Purpose: Providing effective analgesia for total knee arthroplasty (TKA) patients remains challenging. Femoral nerve block (FNB) offers targeted pain control; however, its effect on motor function, related fall risk and impact on rehabilitation has been the source of controversy. Adductor canal block (ACB) potentially ...
0
A Model for Assessing the Clinical and Economic Benefits of Bone-forming Agents for Reducing Fractures in Postmenopausal Women at High, Near-term Risk of Osteoporotic Fracture
Hip Fx in the Elderly 2019
Purpose The goal of this study was to assess and compare the potential clinical and economic value of emerging bone-forming agents using the only currently available agent, teriparatide, as a reference case in patients at high, near-term (imminent, 1- to 2-year) risk of osteoporotic fractures, extending to a lifetime h...
0
Treatment of unusual proximal humeral fractures using unilateral external fixator: a case series
DoD SSI (Surgical Site Infections)
OBJECTIVE: To report the functional and radiological results of unusual comminuted fractures of the proximal humerus, treated with 'closed reduction and external fixation' (CREF) using hybrid-type unilateral external fixators (EFs). PATIENTS AND METHODS: Between January 2012 and June 2013, eight patients (mean age 62.6...
0
Transcultural validation of the Oxford Shoulder Score for the French-speaking population
Glenohumeral Joint OA
PURPOSE: Patient-reported outcome measures (PROMs) have been gaining in popularity over the last decade. The Oxford Shoulder Score (OSS) is a well-established self-administered questionnaire for shoulder evaluation adapted for the English-speaking population. The aim of the present study was to develop a translation an...
0
Factors affecting progenitor cell yields using three tandem leukaphereses in previously treated malignancies
MSTS 2022 - Metastatic Disease of the Humerus
BACKGROUND: Mobilized peripheral blood progenitor cells (PBPCs) have increasingly been used to replace autologous bone marrow to allow faster hematopoietic reconstitution after myeloablative therapy in various malignancies. There is a paucity of data concerning factors that affect the total yield of three tandem leukap...
0
Familial amyloidotic polyneuropathy presenting with carpal tunnel syndrome and a new transthyretin mutation, asparagine 70
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
We report familial amyloidotic polyneuropathy in a pedigree of German ancestry residing in New Jersey. Eight affected subjects presented in the third to seventh decade with carpal tunnel syndrome (CTS) and one subject presented with vitreous opacification. Transmission was autosomal dominant and survival was prolonged....
1
The effect of knee brace on coordination and neuronal leg muscle control: an early postoperative functional study in anterior cruciate ligament reconstructed patients
Anterior Cruciate Ligament Injuries CPG
Two studies were carried out after anterior cruciate ligament (ACL) reconstruction to determine the effect of a knee brace on coordination (test 1) and electromyographic muscle activity in drop jumps (test 2). Test 1 studied 25 patients with ACL reconstruction under three test conditions (one-leg static, two-legged sta...
0
Effects of exercise level on biomarkers in a rat knee model of osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
The aim of this study was to elucidate whether the levels of serum biomarkers reflect the progression of osteoarthritis (OA) induced by different levels of exercise. Thirty-five Wistar rats subjected to anterior cruciate ligament transaction (ACLT) were divided into three groups: Control, moderate running, and intense ...
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Surgical strategy for the treatment of sporadic medullary thyroid carcinoma: our experience
MSTS 2018 - Femur Mets and MM
BACKGROUND: Medullary thyroid carcinoma (MTC) is a rare disease which accounts for approximately 5-9% of all thyroid cancers and originates from the calcitonin-screening parafollicular C cells. MTC can be divided into two subgroups: sporadic (75%) or inherited (25%). The majority of patients with invasive MTC have meta...
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Revision total hip arthroplasty with modular femoral stems
PJI DX Updated Search
As the rate of revision total hip arthroplasty (THA) rises, attention must be paid to potential complications relating to bone loss, soft tissue deficiencies, and loss of tissue planes. Using modular femoral stems in revision surgery allows for varying amounts of bone loss in the proximal and distal femur while letting...
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Internal Fixation of the Distal Humerus: A Comprehensive Biomechanical Study Evaluating Current Fixation Techniques
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
OBJECTIVES:: The purpose of this study was to evaluate current fixation techniques in the operative fixation of distal humerus fractures, both with conventional and locked plating in both parallel and orthogonal orientation. METHODS:: Twenty-eight upper extremities from fourteen cadavers were prepared to create four im...
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STepped Exercise Program for Knee OsteoArthritis
OAK 3 - Non-arthroplasty tx of OAK
Knee osteoarthritis (OA) is a leading cause of pain and disability among Veterans, and Department of Veterans Affairs health care users are the most severely affected. There is ample evidence that exercise improves pain, function, and other outcomes among patients with knee OA. However, the vast majority of individuals...
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Clinical evaluation of arthroscopic-assisted allograft meniscal transplantation
AMP (Acute Meniscal Pathology)
INTRODUCTION: A meniscal deficient knee is at risk of early degenerative osteoarthritis. Allograft meniscal transplantation has been used to treat the meniscus deficiency to alleviate pain symptoms and to delay progression to arthritis. This case series aims to assess the postoperative outcomes of patients who have und...
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Autologous blood injection for treatment of lateral epicondylosis: A meta-analysis of randomized controlled trials
PRPs for Lateral Epicondylitis/Elbow Tendinopathies
OBJECTIVES: To appraise existing evidence of autologous blood injection in treating lateral epicondylosis. DESIGN: Meta-analysis of randomized controlled trials. SETTING: A comprehensive search of the PubMed, Cochrane, SCOPUS, and CINAHL databases was performed to identify randomized controlled trials that reported the...
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Effects of GGCX overexpression on anterior cruciate ligament transection-induced osteoarthritis in rabbits
OAK 3 - Non-arthroplasty tx of OAK
Effective therapeutic methods for osteoarthritis (OA) are lacking. gamma-glutamyl carboxylase (GGCX) is a key enzyme that regulates carboxylation of cartilage matrix Gla protein (MGP). Whether GGCX overexpression protects against OA remains unknown. The aim of the present study was to explore the effects of GGCX overex...
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Meniscal allograft transplantation after meniscectomy: clinical effectiveness and cost-effectiveness
OAK 3 - Non-arthroplasty tx of OAK
PURPOSE: To assess the clinical effectiveness and cost-effectiveness of meniscal allograft transplantation (MAT) after meniscal injury and subsequent meniscectomy. METHODS: Systematic review of clinical effectiveness and cost-effectiveness analysis. RESULTS: There is considerable evidence from observational studies, of...
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Baseline meniscal extrusion associated with incident knee osteoarthritis after 30 months in overweight and obese women
AMP (Acute Meniscal Pathology)
OBJECTIVE: To investigate the association between baseline meniscal extrusion and the incidence of knee osteoarthritis (KOA) after 30 months in a high-risk population of overweight and obese women, free of clinical and radiological KOA at baseline. METHODS: 407 middle-aged overweight women (body mass index - BMI >= 27 ...
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The outcome of cemented vs. cementless fixation of a femoral component in total knee replacement (TKR) with the identification of radiological signs for the prediction of failure
Surgical Management of Osteoarthritis of the Knee CPG
A survival analysis and radiological review were performed on a series of femoral total knee arthroplasty (TKA) prostheses either cemented (150 cases) or cementless, press-fit (201 cases). The internal surface of the femoral components were shot-blast CoCr alloy. The incidence of loosening of the femoral component at 6...
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Changed gait pattern in patients with total knee arthroplasty but minimal influence of tibial insert design: gait analysis during level walking in 39 TKR patients and 18 healthy controls
Management of Hip Fractures in the Elderly
INTRODUCTION: Previous radiostereometric studies have revealed abnormal anterior-posterior translation of the femur in patients operated with AMK (DePuy, Johnson and Johnson, Leeds, UK) total knee arthroplasty (TKA). Based on these observations, we hypothesized that patients with TKA have an abnormal gait pattern, and ...
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A comparative study of medial versus lateral arthroscopic partial meniscectomy on stable knees: 10-year minimum follow-up
AMP (Acute Meniscal Pathology)
PURPOSE: Our goal was to compare results of partial medial arthroscopic meniscectomy with results of partial lateral arthroscopic meniscectomy and to determine prognostic factors. TYPE OF STUDY: Retrospective comparative study with statistical analysis. METHODS: In this study, 362 medial and 109 lateral isolated arthro...
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Management of thoracic insufficiency syndrome in patients with jeune syndrome using the 70mm radius vertical expandable prosthetic titanium rib
DoD SSI (Surgical Site Infections)
Background: Jeune syndrome (JS) often results in lethal thoracic insufficiency syndrome. Since 1991, vertical expandable prosthetic titanium rib Dynamic PosteroLateral Expansion Thoracoplasty was used at our institution for treatment of JS. This study assesses the safety and efficacy of this procedure. Methods: Twenty-...
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Variability in Private Payer Medical Policies for Osteochondral Allograft Transplantation Demonstrates the Absence of Standardization in Medical Criteria Between Payers
Osteochondritis Dissecans 2020 Review
PURPOSE: To define the criteria for coverage for a cartilage restoration procedure and osteochondral allograft (OCA) transplantation and to investigate coverage for OCA procedures among private payer medical policies. METHODS: A systematic search of private payer websites was conducted to identify publicly available 20...
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Long-term NSAID treatment directly decreases COX-2 and mPGES-1 production in the articular cartilage of patients with osteoarthritis
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: To simultaneously study the effect of a selective cyclooxygenase-2 (COX-2) inhibitor and that of a classic non-steroidal anti-inflammatory drug (NSAID) on the expression of pro-inflammatory genes in the cartilage of patients with severe knee osteoarthritis (OA) and in cultured human OA chondrocytes. METHODS:...
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Advances in unicompartmental knee arthroplasty with minimally invasive techniques
Surgical Management of Osteoarthritis of the Knee CPG
Unicompartmental arthroplasty has proved to be a reliable option for monocompartmental arthritis in well selected patients. Unicompartmental knee arthroplasty (UKA) is not a temporary procedure and its ten year survival is comparable to TKA and better than High Tibial Osteotomy. The success of the procedure depends on ...
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Combined lumbar-sacral plexus block in high surgical risk geriatric patients undergoing early hip fracture surgery
AAHKS (8) Anesthetic Infiltration
Objective: To evaluate the postoperative outcome after using combined lumbar and sacral plexus block (CLSB), as a sole anesthetic method in hip fracture (HF) surgery in highrisk geriatric patients. Materials and Methods: A single-center retrospective study was conducted, between 2010 and 2012, on 70 elderly HF patients...
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The Efficacy of Liposomal Bupivacaine Over Traditional Local Anesthetics in Periarticular Infiltration and Regional Anesthesia During Total Knee Arthroplasty: A Systematic Review and Meta-Analysis
AAHKS (4) Acetaminophen
Background: Since its Food and Drug Administration approval in 2011 as a local anesthetic for postsurgical analgesia, liposomal bupivacaine (LB) has been incorporated into the periarticular injection (PAI) of many knee surgeons. The slow release of this medication from vesicles should significantly extend the duration ...
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Arthroscopic visualization of the posterior horn of the medial meniscus
AMP (Acute Meniscal Pathology)
We present a method of visualizing the posterior horn of the medial meniscus through the anterolateral portal that has not been previously described in the literature. It allows easy visualization and instrumentation of the posterior horn, an area that commonly has pathology that can be difficult to identify and treat....
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A Literature Review and Summary Recommendations of the Impact of Bariatric Surgery on Orthopedic Outcomes
DoD SSI (Surgical Site Infections)
Many surgeons recommend weight loss in preparation for orthopedic procedures, yet the impact of surgically induced weight loss before orthopedic procedures is not clear. We undertook a literature review to assess the impact of bariatric surgery on the outcomes of total joint arthroplasty (TJA). We searched PubMed, Medl...
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Placebo-controlled, randomized double-blind study to evaluate the efficacy and tolerability of Rosaxan® in patients with Gonarthrosis
OAK 3 - Non-arthroplasty tx of OAK
INTERVENTION: Intervention 1: Verum: dietary supplements Rosaxan® related to the daily dose of 4 Cl (40 ml) Composition: Rosehip puree 20.0 g Rosehip juice concentrate 4.0 g Nettle extract 160 mg Devil's claw root powder 108 mg Vitamin C (from rose hips) 30 mg Vitamin D 5 µg Manganese 0.5 mg Dosage statement: 1x dail...