prompt stringlengths 725 4.07k | label stringclasses 2
values | revised_title stringlengths 27 257 | revised_abstract stringlengths 261 3.59k | head_chemical_entName stringlengths 1 76 | head_entity_dict dict | tail_disease_entName stringlengths 3 89 | tail_entity_dict dict | chemical_entitiesList listlengths 1 42 | disease_entitiesList listlengths 1 33 | origin_title stringlengths 27 249 | origin_abstract stringlengths 249 3.46k | intra-sentence bool 2
classes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"alpha-methyldopa"/ induces disease /"hypotensive"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Naloxone reverses the antihypertensive effect of clonidine.
- Abstract: In unanesthetized, spo... | Yes | Naloxone reverses the antihypertensive effect of clonidine. | In unanesthetized, spontaneously hypertensive rats the decrease in blood pressure and heart rate produced by intravenous clonidine, 5 to 20 micrograms/kg, was inhibited or reversed by nalozone, 0.2 to 2 mg/kg. The /"hypotensive"/ effect of 100 mg/kg /"alpha-methyldopa"/ was also partially reversed by naloxone. Naloxone... | alpha-methyldopa | {
"id": "9",
"normalized": [
{
"db_id": "D008750",
"db_name": "MESH"
}
],
"offsets": [
[
306,
322
]
],
"text": [
"alpha-methyldopa"
],
"type": "Chemical"
} | hypotensive | {
"id": "8",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
274,
285
]
],
"text": [
"hypotensive"
],
"type": "Disease"
} | [
{
"id": "3",
"normalized": [
{
"db_id": "D009270",
"db_name": "MESH"
}
],
"offsets": [
[
0,
8
]
],
"text": [
"Naloxone"
],
"type": "Chemical"
},
{
"id": "4",
"normalized": [
{
"db_id": "D003000",
... | [
{
"id": "5",
"normalized": [
{
"db_id": "D006973",
"db_name": "MESH"
}
],
"offsets": [
[
93,
105
]
],
"text": [
"hypertensive"
],
"type": "Disease"
},
{
"id": "8",
"normalized": [
{
"db_id": "D007... | Naloxone reverses the antihypertensive effect of clonidine. | In unanesthetized, spontaneously hypertensive rats the decrease in blood pressure and heart rate produced by intravenous clonidine, 5 to 20 micrograms/kg, was inhibited or reversed by nalozone, 0.2 to 2 mg/kg. The hypotensive effect of 100 mg/kg alpha-methyldopa was also partially reversed by naloxone. Naloxone alone d... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"clonidine"/ induces disease /"hypotensive"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Naloxone reverses the antihypertensive effect of /"clonidine"/.
- Abstract: In unanesthetized, sponta... | No | Naloxone reverses the antihypertensive effect of /"clonidine"/. | In unanesthetized, spontaneously hypertensive rats the decrease in blood pressure and heart rate produced by intravenous /"clonidine"/, 5 to 20 micrograms/kg, was inhibited or reversed by nalozone, 0.2 to 2 mg/kg. The /"hypotensive"/ effect of 100 mg/kg alpha-methyldopa was also partially reversed by naloxone. Naloxone... | clonidine | {
"id": "4",
"normalized": [
{
"db_id": "D003000",
"db_name": "MESH"
}
],
"offsets": [
[
49,
58
]
],
"text": [
"clonidine"
],
"type": "Chemical"
} | hypotensive | {
"id": "8",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
274,
285
]
],
"text": [
"hypotensive"
],
"type": "Disease"
} | [
{
"id": "3",
"normalized": [
{
"db_id": "D009270",
"db_name": "MESH"
}
],
"offsets": [
[
0,
8
]
],
"text": [
"Naloxone"
],
"type": "Chemical"
},
{
"id": "4",
"normalized": [
{
"db_id": "D003000",
... | [
{
"id": "5",
"normalized": [
{
"db_id": "D006973",
"db_name": "MESH"
}
],
"offsets": [
[
93,
105
]
],
"text": [
"hypertensive"
],
"type": "Disease"
},
{
"id": "8",
"normalized": [
{
"db_id": "D007... | Naloxone reverses the antihypertensive effect of clonidine. | In unanesthetized, spontaneously hypertensive rats the decrease in blood pressure and heart rate produced by intravenous clonidine, 5 to 20 micrograms/kg, was inhibited or reversed by nalozone, 0.2 to 2 mg/kg. The hypotensive effect of 100 mg/kg alpha-methyldopa was also partially reversed by naloxone. Naloxone alone d... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Lidocaine"/ induces disease /"cardiac asystole"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Lidocaine"/-induced /"cardiac asystole"/.
- Abstract: Intravenous administration of a single 5... | Yes | /"Lidocaine"/-induced /"cardiac asystole"/. | Intravenous administration of a single 50-mg bolus of /"lidocaine"/ in a 67-year-old man resulted in profound depression of the activity of the sinoatrial and atrioventricular nodal pacemakers. The patient had no apparent associated conditions which might have predisposed him to the development of bradyarrhythmias; and... | Lidocaine | {
"id": "28",
"normalized": [
{
"db_id": "D008012",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Lidocaine"
],
"type": "Chemical"
} | cardiac asystole | {
"id": "29",
"normalized": [
{
"db_id": "D006323",
"db_name": "MESH"
}
],
"offsets": [
[
18,
34
]
],
"text": [
"cardiac asystole"
],
"type": "Disease"
} | [
{
"id": "28",
"normalized": [
{
"db_id": "D008012",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Lidocaine"
],
"type": "Chemical"
},
{
"id": "30",
"normalized": [
{
"db_id": "D008012... | [
{
"id": "29",
"normalized": [
{
"db_id": "D006323",
"db_name": "MESH"
}
],
"offsets": [
[
18,
34
]
],
"text": [
"cardiac asystole"
],
"type": "Disease"
},
{
"id": "31",
"normalized": [
{
"db_id": ... | Lidocaine-induced cardiac asystole. | Intravenous administration of a single 50-mg bolus of lidocaine in a 67-year-old man resulted in profound depression of the activity of the sinoatrial and atrioventricular nodal pacemakers. The patient had no apparent associated conditions which might have predisposed him to the development of bradyarrhythmias; and, th... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Lidocaine"/ induces disease /"depression"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Lidocaine"/-induced cardiac asystole.
- Abstract: Intravenous administration of a single 50-mg bolus... | No | /"Lidocaine"/-induced cardiac asystole. | Intravenous administration of a single 50-mg bolus of /"lidocaine"/ in a 67-year-old man resulted in profound /"depression"/ of the activity of the sinoatrial and atrioventricular nodal pacemakers. The patient had no apparent associated conditions which might have predisposed him to the development of bradyarrhythmias;... | Lidocaine | {
"id": "28",
"normalized": [
{
"db_id": "D008012",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Lidocaine"
],
"type": "Chemical"
} | depression | {
"id": "31",
"normalized": [
{
"db_id": "D003866",
"db_name": "MESH"
}
],
"offsets": [
[
142,
152
]
],
"text": [
"depression"
],
"type": "Disease"
} | [
{
"id": "28",
"normalized": [
{
"db_id": "D008012",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Lidocaine"
],
"type": "Chemical"
},
{
"id": "30",
"normalized": [
{
"db_id": "D008012... | [
{
"id": "29",
"normalized": [
{
"db_id": "D006323",
"db_name": "MESH"
}
],
"offsets": [
[
18,
34
]
],
"text": [
"cardiac asystole"
],
"type": "Disease"
},
{
"id": "31",
"normalized": [
{
"db_id": ... | Lidocaine-induced cardiac asystole. | Intravenous administration of a single 50-mg bolus of lidocaine in a 67-year-old man resulted in profound depression of the activity of the sinoatrial and atrioventricular nodal pacemakers. The patient had no apparent associated conditions which might have predisposed him to the development of bradyarrhythmias; and, th... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Suxamethonium"/ induces disease /"fasciculations"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Suxamethonium"/ infusion rate and observed /"fasciculations"/. A dose-response study.
- Abst... | Yes | /"Suxamethonium"/ infusion rate and observed /"fasciculations"/. A dose-response study. | /"Suxamethonium chloride"/ (/"Sch"/) was administered i.v. to 36 adult males at six rates: 0.25 mg s-1 to 20 mg s-1. The infusion was discontinued either when there was no muscular response to tetanic stimulation of the ulnar nerve or when /"Sch"/ 120 mg was exceeded. Six additional patients received a 30-mg i.v. bolus... | Suxamethonium | {
"id": "40",
"normalized": [
{
"db_id": "D013390",
"db_name": "MESH"
}
],
"offsets": [
[
0,
13
]
],
"text": [
"Suxamethonium"
],
"type": "Chemical"
} | fasciculations | {
"id": "41",
"normalized": [
{
"db_id": "D005207",
"db_name": "MESH"
}
],
"offsets": [
[
41,
55
]
],
"text": [
"fasciculations"
],
"type": "Disease"
} | [
{
"id": "40",
"normalized": [
{
"db_id": "D013390",
"db_name": "MESH"
}
],
"offsets": [
[
0,
13
]
],
"text": [
"Suxamethonium"
],
"type": "Chemical"
},
{
"id": "42",
"normalized": [
{
"db_id": "D0... | [
{
"id": "41",
"normalized": [
{
"db_id": "D005207",
"db_name": "MESH"
}
],
"offsets": [
[
41,
55
]
],
"text": [
"fasciculations"
],
"type": "Disease"
},
{
"id": "44",
"normalized": [
{
"db_id": "D... | Suxamethonium infusion rate and observed fasciculations. A dose-response study. | Suxamethonium chloride (Sch) was administered i.v. to 36 adult males at six rates: 0.25 mg s-1 to 20 mg s-1. The infusion was discontinued either when there was no muscular response to tetanic stimulation of the ulnar nerve or when Sch 120 mg was exceeded. Six additional patients received a 30-mg i.v. bolus dose. Fasci... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Suxamethonium"/ induces disease /"tetanic"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Suxamethonium"/ infusion rate and observed fasciculations. A dose-response study.
- Abstract: /"Sux... | No | /"Suxamethonium"/ infusion rate and observed fasciculations. A dose-response study. | /"Suxamethonium chloride"/ (/"Sch"/) was administered i.v. to 36 adult males at six rates: 0.25 mg s-1 to 20 mg s-1. The infusion was discontinued either when there was no muscular response to /"tetanic"/ stimulation of the ulnar nerve or when /"Sch"/ 120 mg was exceeded. Six additional patients received a 30-mg i.v. b... | Suxamethonium | {
"id": "40",
"normalized": [
{
"db_id": "D013390",
"db_name": "MESH"
}
],
"offsets": [
[
0,
13
]
],
"text": [
"Suxamethonium"
],
"type": "Chemical"
} | tetanic | {
"id": "44",
"normalized": [
{
"db_id": "D013746",
"db_name": "MESH"
}
],
"offsets": [
[
265,
272
]
],
"text": [
"tetanic"
],
"type": "Disease"
} | [
{
"id": "40",
"normalized": [
{
"db_id": "D013390",
"db_name": "MESH"
}
],
"offsets": [
[
0,
13
]
],
"text": [
"Suxamethonium"
],
"type": "Chemical"
},
{
"id": "42",
"normalized": [
{
"db_id": "D0... | [
{
"id": "41",
"normalized": [
{
"db_id": "D005207",
"db_name": "MESH"
}
],
"offsets": [
[
41,
55
]
],
"text": [
"fasciculations"
],
"type": "Disease"
},
{
"id": "44",
"normalized": [
{
"db_id": "D... | Suxamethonium infusion rate and observed fasciculations. A dose-response study. | Suxamethonium chloride (Sch) was administered i.v. to 36 adult males at six rates: 0.25 mg s-1 to 20 mg s-1. The infusion was discontinued either when there was no muscular response to tetanic stimulation of the ulnar nerve or when Sch 120 mg was exceeded. Six additional patients received a 30-mg i.v. bolus dose. Fasci... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"scopolamine"/ induces disease /"overdosage"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of the central ... | Yes | Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of the central effects of /"scopolamine"/ (/"Hyoscine"/). | Galanthamine hydrobromide, an anticholinesterase drug capable of penetrating the blood-brain barrier, was used in a patient demonstrating central effects of /"scopolamine"/ (/"hyoscine"/) /"overdosage"/. It is longer acting than physostigmine and is used in anaesthesia to reverse the non-depolarizing neuromuscular bloc... | scopolamine | {
"id": "86",
"normalized": [
{
"db_id": "D012601",
"db_name": "MESH"
}
],
"offsets": [
[
111,
122
]
],
"text": [
"scopolamine"
],
"type": "Chemical"
} | overdosage | {
"id": "91",
"normalized": [
{
"db_id": "D062787",
"db_name": "MESH"
}
],
"offsets": [
[
315,
325
]
],
"text": [
"overdosage"
],
"type": "Disease"
} | [
{
"id": "85",
"normalized": [
{
"db_id": "D005702",
"db_name": "MESH"
}
],
"offsets": [
[
0,
25
]
],
"text": [
"Galanthamine hydrobromide"
],
"type": "Chemical"
},
{
"id": "86",
"normalized": [
{
... | [
{
"id": "91",
"normalized": [
{
"db_id": "D062787",
"db_name": "MESH"
}
],
"offsets": [
[
315,
325
]
],
"text": [
"overdosage"
],
"type": "Disease"
}
] | Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of the central effects of scopolamine (Hyoscine). | Galanthamine hydrobromide, an anticholinesterase drug capable of penetrating the blood-brain barrier, was used in a patient demonstrating central effects of scopolamine (hyoscine) overdosage. It is longer acting than physostigmine and is used in anaesthesia to reverse the non-depolarizing neuromuscular block. However, ... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"physostigmine"/ induces disease /"overdosage"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of the centra... | No | Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of the central effects of scopolamine (Hyoscine). | Galanthamine hydrobromide, an anticholinesterase drug capable of penetrating the blood-brain barrier, was used in a patient demonstrating central effects of scopolamine (hyoscine) /"overdosage"/. It is longer acting than /"physostigmine"/ and is used in anaesthesia to reverse the non-depolarizing neuromuscular block. H... | physostigmine | {
"id": "92",
"normalized": [
{
"db_id": "D010830",
"db_name": "MESH"
}
],
"offsets": [
[
352,
365
]
],
"text": [
"physostigmine"
],
"type": "Chemical"
} | overdosage | {
"id": "91",
"normalized": [
{
"db_id": "D062787",
"db_name": "MESH"
}
],
"offsets": [
[
315,
325
]
],
"text": [
"overdosage"
],
"type": "Disease"
} | [
{
"id": "85",
"normalized": [
{
"db_id": "D005702",
"db_name": "MESH"
}
],
"offsets": [
[
0,
25
]
],
"text": [
"Galanthamine hydrobromide"
],
"type": "Chemical"
},
{
"id": "86",
"normalized": [
{
... | [
{
"id": "91",
"normalized": [
{
"db_id": "D062787",
"db_name": "MESH"
}
],
"offsets": [
[
315,
325
]
],
"text": [
"overdosage"
],
"type": "Disease"
}
] | Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of the central effects of scopolamine (Hyoscine). | Galanthamine hydrobromide, an anticholinesterase drug capable of penetrating the blood-brain barrier, was used in a patient demonstrating central effects of scopolamine (hyoscine) overdosage. It is longer acting than physostigmine and is used in anaesthesia to reverse the non-depolarizing neuromuscular block. However, ... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"lithium"/ induces disease /"hypertension"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Effects of uninephrectomy and high protein feeding on /"lithium"/-induced chronic renal failure in rat... | Yes | Effects of uninephrectomy and high protein feeding on /"lithium"/-induced chronic renal failure in rats. | Rats with /"lithium"/-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a /"lithium"/-containing diet (50 mmol/kg) for 8 weeks an... | lithium | {
"id": "102",
"normalized": [
{
"db_id": "D008094",
"db_name": "MESH"
}
],
"offsets": [
[
54,
61
]
],
"text": [
"lithium"
],
"type": "Chemical"
} | hypertension | {
"id": "117",
"normalized": [
{
"db_id": "D006973",
"db_name": "MESH"
}
],
"offsets": [
[
1000,
1012
]
],
"text": [
"hypertension"
],
"type": "Disease"
} | [
{
"id": "102",
"normalized": [
{
"db_id": "D008094",
"db_name": "MESH"
}
],
"offsets": [
[
54,
61
]
],
"text": [
"lithium"
],
"type": "Chemical"
},
{
"id": "104",
"normalized": [
{
"db_id": "D0080... | [
{
"id": "103",
"normalized": [
{
"db_id": "D007676",
"db_name": "MESH"
}
],
"offsets": [
[
70,
91
]
],
"text": [
"chronic renal failure"
],
"type": "Disease"
},
{
"id": "105",
"normalized": [
{
"d... | Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats. | Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a lithium-containing diet (50 mmol/kg) for 8 weeks and then r... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"lithium"/ induces disease /"proteinuria"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Effects of uninephrectomy and high protein feeding on /"lithium"/-induced chronic renal failure in rats... | Yes | Effects of uninephrectomy and high protein feeding on /"lithium"/-induced chronic renal failure in rats. | Rats with /"lithium"/-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a /"lithium"/-containing diet (50 mmol/kg) for 8 weeks an... | lithium | {
"id": "102",
"normalized": [
{
"db_id": "D008094",
"db_name": "MESH"
}
],
"offsets": [
[
54,
61
]
],
"text": [
"lithium"
],
"type": "Chemical"
} | proteinuria | {
"id": "116",
"normalized": [
{
"db_id": "D011507",
"db_name": "MESH"
}
],
"offsets": [
[
975,
986
]
],
"text": [
"proteinuria"
],
"type": "Disease"
} | [
{
"id": "102",
"normalized": [
{
"db_id": "D008094",
"db_name": "MESH"
}
],
"offsets": [
[
54,
61
]
],
"text": [
"lithium"
],
"type": "Chemical"
},
{
"id": "104",
"normalized": [
{
"db_id": "D0080... | [
{
"id": "103",
"normalized": [
{
"db_id": "D007676",
"db_name": "MESH"
}
],
"offsets": [
[
70,
91
]
],
"text": [
"chronic renal failure"
],
"type": "Disease"
},
{
"id": "105",
"normalized": [
{
"d... | Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats. | Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a lithium-containing diet (50 mmol/kg) for 8 weeks and then r... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"lithium"/ induces disease /"chronic renal failure"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Effects of uninephrectomy and high protein feeding on /"lithium"/-induced /"chronic renal fai... | Yes | Effects of uninephrectomy and high protein feeding on /"lithium"/-induced /"chronic renal failure"/ in rats. | Rats with /"lithium"/-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a /"lithium"/-containing diet (50 mmol/kg) for 8 weeks an... | lithium | {
"id": "102",
"normalized": [
{
"db_id": "D008094",
"db_name": "MESH"
}
],
"offsets": [
[
54,
61
]
],
"text": [
"lithium"
],
"type": "Chemical"
} | chronic renal failure | {
"id": "103",
"normalized": [
{
"db_id": "D007676",
"db_name": "MESH"
}
],
"offsets": [
[
70,
91
]
],
"text": [
"chronic renal failure"
],
"type": "Disease"
} | [
{
"id": "102",
"normalized": [
{
"db_id": "D008094",
"db_name": "MESH"
}
],
"offsets": [
[
54,
61
]
],
"text": [
"lithium"
],
"type": "Chemical"
},
{
"id": "104",
"normalized": [
{
"db_id": "D0080... | [
{
"id": "103",
"normalized": [
{
"db_id": "D007676",
"db_name": "MESH"
}
],
"offsets": [
[
70,
91
]
],
"text": [
"chronic renal failure"
],
"type": "Disease"
},
{
"id": "105",
"normalized": [
{
"d... | Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats. | Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a lithium-containing diet (50 mmol/kg) for 8 weeks and then r... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"lithium"/ induces disease /"glomerulosclerosis"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Effects of uninephrectomy and high protein feeding on /"lithium"/-induced chronic renal failure ... | No | Effects of uninephrectomy and high protein feeding on /"lithium"/-induced chronic renal failure in rats. | Rats with /"lithium"/-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a /"lithium"/-containing diet (50 mmol/kg) for 8 weeks an... | lithium | {
"id": "102",
"normalized": [
{
"db_id": "D008094",
"db_name": "MESH"
}
],
"offsets": [
[
54,
61
]
],
"text": [
"lithium"
],
"type": "Chemical"
} | glomerulosclerosis | {
"id": "118",
"normalized": [
{
"db_id": "D005921",
"db_name": "MESH"
}
],
"offsets": [
[
1027,
1045
]
],
"text": [
"glomerulosclerosis"
],
"type": "Disease"
} | [
{
"id": "102",
"normalized": [
{
"db_id": "D008094",
"db_name": "MESH"
}
],
"offsets": [
[
54,
61
]
],
"text": [
"lithium"
],
"type": "Chemical"
},
{
"id": "104",
"normalized": [
{
"db_id": "D0080... | [
{
"id": "103",
"normalized": [
{
"db_id": "D007676",
"db_name": "MESH"
}
],
"offsets": [
[
70,
91
]
],
"text": [
"chronic renal failure"
],
"type": "Disease"
},
{
"id": "105",
"normalized": [
{
"d... | Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats. | Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a lithium-containing diet (50 mmol/kg) for 8 weeks and then r... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"creatinine"/ induces disease /"renal failure"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rat... | No | Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats. | Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of /"renal failure"/. Newborn female Wistar rats were fed a lithium-containing diet (50 mmol/kg) for 8 weeks and th... | creatinine | {
"id": "120",
"normalized": [
{
"db_id": "D003404",
"db_name": "MESH"
}
],
"offsets": [
[
1156,
1166
]
],
"text": [
"creatinine"
],
"type": "Chemical"
} | renal failure | {
"id": "106",
"normalized": [
{
"db_id": "D051437",
"db_name": "MESH"
}
],
"offsets": [
[
309,
322
]
],
"text": [
"renal failure"
],
"type": "Disease"
} | [
{
"id": "102",
"normalized": [
{
"db_id": "D008094",
"db_name": "MESH"
}
],
"offsets": [
[
54,
61
]
],
"text": [
"lithium"
],
"type": "Chemical"
},
{
"id": "104",
"normalized": [
{
"db_id": "D0080... | [
{
"id": "103",
"normalized": [
{
"db_id": "D007676",
"db_name": "MESH"
}
],
"offsets": [
[
70,
91
]
],
"text": [
"chronic renal failure"
],
"type": "Disease"
},
{
"id": "105",
"normalized": [
{
"d... | Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats. | Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a lithium-containing diet (50 mmol/kg) for 8 weeks and then r... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"creatinine"/ induces disease /"nephropathy"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats.... | No | Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats. | Rats with lithium-induced /"nephropathy"/ were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a lithium-containing diet (50 mmol/kg) for 8 weeks and th... | creatinine | {
"id": "120",
"normalized": [
{
"db_id": "D003404",
"db_name": "MESH"
}
],
"offsets": [
[
1156,
1166
]
],
"text": [
"creatinine"
],
"type": "Chemical"
} | nephropathy | {
"id": "105",
"normalized": [
{
"db_id": "D007674",
"db_name": "MESH"
}
],
"offsets": [
[
127,
138
]
],
"text": [
"nephropathy"
],
"type": "Disease"
} | [
{
"id": "102",
"normalized": [
{
"db_id": "D008094",
"db_name": "MESH"
}
],
"offsets": [
[
54,
61
]
],
"text": [
"lithium"
],
"type": "Chemical"
},
{
"id": "104",
"normalized": [
{
"db_id": "D0080... | [
{
"id": "103",
"normalized": [
{
"db_id": "D007676",
"db_name": "MESH"
}
],
"offsets": [
[
70,
91
]
],
"text": [
"chronic renal failure"
],
"type": "Disease"
},
{
"id": "105",
"normalized": [
{
"d... | Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats. | Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a lithium-containing diet (50 mmol/kg) for 8 weeks and then r... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"fusidic acid"/ induces disease /"nausea"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Treatment of Crohn's disease with /"fusidic acid"/: an antibiotic with immunosuppressive properties sim... | Yes | Treatment of Crohn's disease with /"fusidic acid"/: an antibiotic with immunosuppressive properties similar to cyclosporin. | Fusidic acid is an antibiotic with T-cell specific immunosuppressive effects similar to those of cyclosporin. Because of the need for the development of new treatments for Crohn's disease, a pilot study was undertaken to estimate the pharmacodynamics and tolerability of /"fusidic acid"/ treatment in chronic active, the... | fusidic acid | {
"id": "216",
"normalized": [
{
"db_id": "D005672",
"db_name": "MESH"
}
],
"offsets": [
[
34,
46
]
],
"text": [
"fusidic acid"
],
"type": "Chemical"
} | nausea | {
"id": "224",
"normalized": [
{
"db_id": "D009325",
"db_name": "MESH"
}
],
"offsets": [
[
910,
916
]
],
"text": [
"nausea"
],
"type": "Disease"
} | [
{
"id": "216",
"normalized": [
{
"db_id": "D005672",
"db_name": "MESH"
}
],
"offsets": [
[
34,
46
]
],
"text": [
"fusidic acid"
],
"type": "Chemical"
},
{
"id": "217",
"normalized": [
{
"db_id": "... | [
{
"id": "215",
"normalized": [
{
"db_id": "D003424",
"db_name": "MESH"
}
],
"offsets": [
[
13,
28
]
],
"text": [
"Crohn's disease"
],
"type": "Disease"
},
{
"id": "219",
"normalized": [
{
"db_id":... | Treatment of Crohn's disease with fusidic acid: an antibiotic with immunosuppressive properties similar to cyclosporin. | Fusidic acid is an antibiotic with T-cell specific immunosuppressive effects similar to those of cyclosporin. Because of the need for the development of new treatments for Crohn's disease, a pilot study was undertaken to estimate the pharmacodynamics and tolerability of fusidic acid treatment in chronic active, therapy... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"fusidic acid"/ induces disease /"inflammatory bowel disease"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Treatment of Crohn's disease with /"fusidic acid"/: an antibiotic with immunosuppre... | No | Treatment of Crohn's disease with /"fusidic acid"/: an antibiotic with immunosuppressive properties similar to cyclosporin. | Fusidic acid is an antibiotic with T-cell specific immunosuppressive effects similar to those of cyclosporin. Because of the need for the development of new treatments for Crohn's disease, a pilot study was undertaken to estimate the pharmacodynamics and tolerability of /"fusidic acid"/ treatment in chronic active, the... | fusidic acid | {
"id": "216",
"normalized": [
{
"db_id": "D005672",
"db_name": "MESH"
}
],
"offsets": [
[
34,
46
]
],
"text": [
"fusidic acid"
],
"type": "Chemical"
} | inflammatory bowel disease | {
"id": "228",
"normalized": [
{
"db_id": "D015212",
"db_name": "MESH"
}
],
"offsets": [
[
1440,
1466
]
],
"text": [
"inflammatory bowel disease"
],
"type": "Disease"
} | [
{
"id": "216",
"normalized": [
{
"db_id": "D005672",
"db_name": "MESH"
}
],
"offsets": [
[
34,
46
]
],
"text": [
"fusidic acid"
],
"type": "Chemical"
},
{
"id": "217",
"normalized": [
{
"db_id": "... | [
{
"id": "215",
"normalized": [
{
"db_id": "D003424",
"db_name": "MESH"
}
],
"offsets": [
[
13,
28
]
],
"text": [
"Crohn's disease"
],
"type": "Disease"
},
{
"id": "219",
"normalized": [
{
"db_id":... | Treatment of Crohn's disease with fusidic acid: an antibiotic with immunosuppressive properties similar to cyclosporin. | Fusidic acid is an antibiotic with T-cell specific immunosuppressive effects similar to those of cyclosporin. Because of the need for the development of new treatments for Crohn's disease, a pilot study was undertaken to estimate the pharmacodynamics and tolerability of fusidic acid treatment in chronic active, therapy... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"cocaine"/ induces disease /"myocardial infarction"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized /"cocaine"... | Yes | Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized /"cocaine"/ abusers. | The electrocardiograms (ECG) of 99 /"cocaine"/-abusing patients were compared with the ECGs of 50 schizophrenic controls. Eleven of the /"cocaine"/ abusers and none of the controls had ECG evidence of significant myocardial injury defined as /"myocardial infarction"/, ischemia, and bundle branch block. | cocaine | {
"id": "239",
"normalized": [
{
"db_id": "D003042",
"db_name": "MESH"
}
],
"offsets": [
[
83,
90
]
],
"text": [
"cocaine"
],
"type": "Chemical"
} | myocardial infarction | {
"id": "244",
"normalized": [
{
"db_id": "D009203",
"db_name": "MESH"
}
],
"offsets": [
[
334,
355
]
],
"text": [
"myocardial infarction"
],
"type": "Disease"
} | [
{
"id": "239",
"normalized": [
{
"db_id": "D003042",
"db_name": "MESH"
}
],
"offsets": [
[
83,
90
]
],
"text": [
"cocaine"
],
"type": "Chemical"
},
{
"id": "240",
"normalized": [
{
"db_id": "D0030... | [
{
"id": "238",
"normalized": [
{
"db_id": "D009202",
"db_name": "MESH"
}
],
"offsets": [
[
33,
50
]
],
"text": [
"myocardial injury"
],
"type": "Disease"
},
{
"id": "241",
"normalized": [
{
"db_id... | Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized cocaine abusers. | The electrocardiograms (ECG) of 99 cocaine-abusing patients were compared with the ECGs of 50 schizophrenic controls. Eleven of the cocaine abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block. | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"cocaine"/ induces disease /"bundle branch block"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized /"cocaine"/ ... | Yes | Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized /"cocaine"/ abusers. | The electrocardiograms (ECG) of 99 /"cocaine"/-abusing patients were compared with the ECGs of 50 schizophrenic controls. Eleven of the /"cocaine"/ abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and /"bundle branch block"/. | cocaine | {
"id": "239",
"normalized": [
{
"db_id": "D003042",
"db_name": "MESH"
}
],
"offsets": [
[
83,
90
]
],
"text": [
"cocaine"
],
"type": "Chemical"
} | bundle branch block | {
"id": "246",
"normalized": [
{
"db_id": "D002037",
"db_name": "MESH"
}
],
"offsets": [
[
371,
390
]
],
"text": [
"bundle branch block"
],
"type": "Disease"
} | [
{
"id": "239",
"normalized": [
{
"db_id": "D003042",
"db_name": "MESH"
}
],
"offsets": [
[
83,
90
]
],
"text": [
"cocaine"
],
"type": "Chemical"
},
{
"id": "240",
"normalized": [
{
"db_id": "D0030... | [
{
"id": "238",
"normalized": [
{
"db_id": "D009202",
"db_name": "MESH"
}
],
"offsets": [
[
33,
50
]
],
"text": [
"myocardial injury"
],
"type": "Disease"
},
{
"id": "241",
"normalized": [
{
"db_id... | Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized cocaine abusers. | The electrocardiograms (ECG) of 99 cocaine-abusing patients were compared with the ECGs of 50 schizophrenic controls. Eleven of the cocaine abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block. | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"cocaine"/ induces disease /"ischemia"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized /"cocaine"/ abusers.
- ... | No | Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized /"cocaine"/ abusers. | The electrocardiograms (ECG) of 99 /"cocaine"/-abusing patients were compared with the ECGs of 50 schizophrenic controls. Eleven of the /"cocaine"/ abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, /"ischemia"/, and bundle branch block. | cocaine | {
"id": "239",
"normalized": [
{
"db_id": "D003042",
"db_name": "MESH"
}
],
"offsets": [
[
83,
90
]
],
"text": [
"cocaine"
],
"type": "Chemical"
} | ischemia | {
"id": "245",
"normalized": [
{
"db_id": "D007511",
"db_name": "MESH"
}
],
"offsets": [
[
357,
365
]
],
"text": [
"ischemia"
],
"type": "Disease"
} | [
{
"id": "239",
"normalized": [
{
"db_id": "D003042",
"db_name": "MESH"
}
],
"offsets": [
[
83,
90
]
],
"text": [
"cocaine"
],
"type": "Chemical"
},
{
"id": "240",
"normalized": [
{
"db_id": "D0030... | [
{
"id": "238",
"normalized": [
{
"db_id": "D009202",
"db_name": "MESH"
}
],
"offsets": [
[
33,
50
]
],
"text": [
"myocardial injury"
],
"type": "Disease"
},
{
"id": "241",
"normalized": [
{
"db_id... | Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized cocaine abusers. | The electrocardiograms (ECG) of 99 cocaine-abusing patients were compared with the ECGs of 50 schizophrenic controls. Eleven of the cocaine abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block. | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"cocaine"/ induces disease /"myocardial injury"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Electrocardiographic evidence of /"myocardial injury"/ in psychiatrically hospitalized /"cocaine"... | No | Electrocardiographic evidence of /"myocardial injury"/ in psychiatrically hospitalized /"cocaine"/ abusers. | The electrocardiograms (ECG) of 99 /"cocaine"/-abusing patients were compared with the ECGs of 50 schizophrenic controls. Eleven of the /"cocaine"/ abusers and none of the controls had ECG evidence of significant /"myocardial injury"/ defined as myocardial infarction, ischemia, and bundle branch block. | cocaine | {
"id": "239",
"normalized": [
{
"db_id": "D003042",
"db_name": "MESH"
}
],
"offsets": [
[
83,
90
]
],
"text": [
"cocaine"
],
"type": "Chemical"
} | myocardial injury | {
"id": "238",
"normalized": [
{
"db_id": "D009202",
"db_name": "MESH"
}
],
"offsets": [
[
33,
50
]
],
"text": [
"myocardial injury"
],
"type": "Disease"
} | [
{
"id": "239",
"normalized": [
{
"db_id": "D003042",
"db_name": "MESH"
}
],
"offsets": [
[
83,
90
]
],
"text": [
"cocaine"
],
"type": "Chemical"
},
{
"id": "240",
"normalized": [
{
"db_id": "D0030... | [
{
"id": "238",
"normalized": [
{
"db_id": "D009202",
"db_name": "MESH"
}
],
"offsets": [
[
33,
50
]
],
"text": [
"myocardial injury"
],
"type": "Disease"
},
{
"id": "241",
"normalized": [
{
"db_id... | Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized cocaine abusers. | The electrocardiograms (ECG) of 99 cocaine-abusing patients were compared with the ECGs of 50 schizophrenic controls. Eleven of the cocaine abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block. | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Sulpiride"/ induces disease /"tardive dystonia"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Sulpiride"/-induced /"tardive dystonia"/.
- Abstract: /"Sulpiride"/ is a selective D2-receptor... | Yes | /"Sulpiride"/-induced /"tardive dystonia"/. | /"Sulpiride"/ is a selective D2-receptor antagonist with antipsychotic and antidepressant properties. Although initially thought to be free of extrapyramidal side effects, /"sulpiride"/-induced tardive dyskinesia and parkinsonism have been reported occasionally. We studied a 37-year-old man who developed persistent seg... | Sulpiride | {
"id": "256",
"normalized": [
{
"db_id": "D013469",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Sulpiride"
],
"type": "Chemical"
} | tardive dystonia | {
"id": "257",
"normalized": [
{
"db_id": "D004421",
"db_name": "MESH"
}
],
"offsets": [
[
18,
34
]
],
"text": [
"tardive dystonia"
],
"type": "Disease"
} | [
{
"id": "256",
"normalized": [
{
"db_id": "D013469",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Sulpiride"
],
"type": "Chemical"
},
{
"id": "258",
"normalized": [
{
"db_id": "D0134... | [
{
"id": "257",
"normalized": [
{
"db_id": "D004421",
"db_name": "MESH"
}
],
"offsets": [
[
18,
34
]
],
"text": [
"tardive dystonia"
],
"type": "Disease"
},
{
"id": "261",
"normalized": [
{
"db_id"... | Sulpiride-induced tardive dystonia. | Sulpiride is a selective D2-receptor antagonist with antipsychotic and antidepressant properties. Although initially thought to be free of extrapyramidal side effects, sulpiride-induced tardive dyskinesia and parkinsonism have been reported occasionally. We studied a 37-year-old man who developed persistent segmental d... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Sulpiride"/ induces disease /"parkinsonism"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Sulpiride"/-induced tardive dystonia.
- Abstract: /"Sulpiride"/ is a selective D2-receptor antagon... | No | /"Sulpiride"/-induced tardive dystonia. | /"Sulpiride"/ is a selective D2-receptor antagonist with antipsychotic and antidepressant properties. Although initially thought to be free of extrapyramidal side effects, /"sulpiride"/-induced tardive dyskinesia and /"parkinsonism"/ have been reported occasionally. We studied a 37-year-old man who developed persistent... | Sulpiride | {
"id": "256",
"normalized": [
{
"db_id": "D013469",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Sulpiride"
],
"type": "Chemical"
} | parkinsonism | {
"id": "262",
"normalized": [
{
"db_id": "D010302",
"db_name": "MESH"
}
],
"offsets": [
[
245,
257
]
],
"text": [
"parkinsonism"
],
"type": "Disease"
} | [
{
"id": "256",
"normalized": [
{
"db_id": "D013469",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Sulpiride"
],
"type": "Chemical"
},
{
"id": "258",
"normalized": [
{
"db_id": "D0134... | [
{
"id": "257",
"normalized": [
{
"db_id": "D004421",
"db_name": "MESH"
}
],
"offsets": [
[
18,
34
]
],
"text": [
"tardive dystonia"
],
"type": "Disease"
},
{
"id": "261",
"normalized": [
{
"db_id"... | Sulpiride-induced tardive dystonia. | Sulpiride is a selective D2-receptor antagonist with antipsychotic and antidepressant properties. Although initially thought to be free of extrapyramidal side effects, sulpiride-induced tardive dyskinesia and parkinsonism have been reported occasionally. We studied a 37-year-old man who developed persistent segmental d... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"desferrioxamine"/ induces disease /"pigmentary retinal deposits"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Ocular and auditory toxicity in hemodialyzed patients receiving /"desferrioxami... | Yes | Ocular and auditory toxicity in hemodialyzed patients receiving /"desferrioxamine"/. | During an 18-month period of study 41 hemodialyzed patients receiving /"desferrioxamine"/ (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of visual or auditory toxicity. Moreover, detailed ophthalmologic and audiologic studi... | desferrioxamine | {
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
} | pigmentary retinal deposits | {
"id": "297",
"normalized": [
{
"db_id": "D012164",
"db_name": "MESH"
}
],
"offsets": [
[
604,
631
]
],
"text": [
"pigmentary retinal deposits"
],
"type": "Disease"
} | [
{
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
},
{
"id": "289",
"normalized": [
{
"db_id"... | [
{
"id": "285",
"normalized": [
{
"db_id": "D014786",
"db_name": "MESH"
},
{
"db_id": "D006311",
"db_name": "MESH"
}
],
"offsets": [
[
0,
28
]
],
"text": [
"Ocular and auditory toxicity"
],
"type... | Ocular and auditory toxicity in hemodialyzed patients receiving desferrioxamine. | During an 18-month period of study 41 hemodialyzed patients receiving desferrioxamine (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of visual or auditory toxicity. Moreover, detailed ophthalmologic and audiologic studies d... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"desferrioxamine"/ induces disease /"Ocular and auditory toxicity"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Ocular and auditory toxicity"/ in hemodialyzed patients receiving /"desferri... | Yes | /"Ocular and auditory toxicity"/ in hemodialyzed patients receiving /"desferrioxamine"/. | During an 18-month period of study 41 hemodialyzed patients receiving /"desferrioxamine"/ (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of /"audiovisual toxicity"/. 6 patients presented clinical symptoms of /"visual or auditory toxicity"/. Moreover, detailed ophthalmologic and audiolog... | desferrioxamine | {
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
} | Ocular and auditory toxicity | {
"id": "285",
"normalized": [
{
"db_id": "D014786",
"db_name": "MESH"
},
{
"db_id": "D006311",
"db_name": "MESH"
}
],
"offsets": [
[
0,
28
]
],
"text": [
"Ocular and auditory toxicity"
],
"type": "Disease"
} | [
{
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
},
{
"id": "289",
"normalized": [
{
"db_id"... | [
{
"id": "285",
"normalized": [
{
"db_id": "D014786",
"db_name": "MESH"
},
{
"db_id": "D006311",
"db_name": "MESH"
}
],
"offsets": [
[
0,
28
]
],
"text": [
"Ocular and auditory toxicity"
],
"type... | Ocular and auditory toxicity in hemodialyzed patients receiving desferrioxamine. | During an 18-month period of study 41 hemodialyzed patients receiving desferrioxamine (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of visual or auditory toxicity. Moreover, detailed ophthalmologic and audiologic studies d... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"desferrioxamine"/ induces disease /"Ocular"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Ocular"/ and auditory /"Ocular"/ in hemodialyzed patients receiving /"desferrioxamine"/.
- Abstrac... | Yes | /"Ocular"/ and auditory /"Ocular"/ in hemodialyzed patients receiving /"desferrioxamine"/. | During an 18-month period of study 41 hemodialyzed patients receiving /"desferrioxamine"/ (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of /"visual"/ or auditory /"visual"/. Moreover, detailed ophthalmologic and audiologic... | desferrioxamine | {
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
} | Ocular | {
"id": "286",
"normalized": [
{
"db_id": "D014786",
"db_name": "MESH"
}
],
"offsets": [
[
0,
6
],
[
20,
28
]
],
"text": [
"Ocular",
"toxicity"
],
"type": "Disease"
} | [
{
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
},
{
"id": "289",
"normalized": [
{
"db_id"... | [
{
"id": "285",
"normalized": [
{
"db_id": "D014786",
"db_name": "MESH"
},
{
"db_id": "D006311",
"db_name": "MESH"
}
],
"offsets": [
[
0,
28
]
],
"text": [
"Ocular and auditory toxicity"
],
"type... | Ocular and auditory toxicity in hemodialyzed patients receiving desferrioxamine. | During an 18-month period of study 41 hemodialyzed patients receiving desferrioxamine (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of visual or auditory toxicity. Moreover, detailed ophthalmologic and audiologic studies d... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"desferrioxamine"/ induces disease /"neurosensorial hearing loss"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Ocular and auditory toxicity in hemodialyzed patients receiving /"desferrioxami... | Yes | Ocular and auditory toxicity in hemodialyzed patients receiving /"desferrioxamine"/. | During an 18-month period of study 41 hemodialyzed patients receiving /"desferrioxamine"/ (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of visual or auditory toxicity. Moreover, detailed ophthalmologic and audiologic studi... | desferrioxamine | {
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
} | neurosensorial hearing loss | {
"id": "299",
"normalized": [
{
"db_id": "D006319",
"db_name": "MESH"
}
],
"offsets": [
[
697,
724
]
],
"text": [
"neurosensorial hearing loss"
],
"type": "Disease"
} | [
{
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
},
{
"id": "289",
"normalized": [
{
"db_id"... | [
{
"id": "285",
"normalized": [
{
"db_id": "D014786",
"db_name": "MESH"
},
{
"db_id": "D006311",
"db_name": "MESH"
}
],
"offsets": [
[
0,
28
]
],
"text": [
"Ocular and auditory toxicity"
],
"type... | Ocular and auditory toxicity in hemodialyzed patients receiving desferrioxamine. | During an 18-month period of study 41 hemodialyzed patients receiving desferrioxamine (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of visual or auditory toxicity. Moreover, detailed ophthalmologic and audiologic studies d... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"desferrioxamine"/ induces disease /"toxicity"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Ocular and auditory toxicity in hemodialyzed patients receiving /"desferrioxamine"/.
- Abstract: D... | No | Ocular and auditory toxicity in hemodialyzed patients receiving /"desferrioxamine"/. | During an 18-month period of study 41 hemodialyzed patients receiving /"desferrioxamine"/ (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of visual or auditory toxicity. Moreover, detailed ophthalmologic and audiologic studi... | desferrioxamine | {
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
} | toxicity | {
"id": "302",
"normalized": [
{
"db_id": "D064420",
"db_name": "MESH"
}
],
"offsets": [
[
970,
978
]
],
"text": [
"toxicity"
],
"type": "Disease"
} | [
{
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
},
{
"id": "289",
"normalized": [
{
"db_id"... | [
{
"id": "285",
"normalized": [
{
"db_id": "D014786",
"db_name": "MESH"
},
{
"db_id": "D006311",
"db_name": "MESH"
}
],
"offsets": [
[
0,
28
]
],
"text": [
"Ocular and auditory toxicity"
],
"type... | Ocular and auditory toxicity in hemodialyzed patients receiving desferrioxamine. | During an 18-month period of study 41 hemodialyzed patients receiving desferrioxamine (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of visual or auditory toxicity. Moreover, detailed ophthalmologic and audiologic studies d... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"desferrioxamine"/ induces disease /"hearing loss"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Ocular and auditory toxicity in hemodialyzed patients receiving /"desferrioxamine"/.
- Abstrac... | No | Ocular and auditory toxicity in hemodialyzed patients receiving /"desferrioxamine"/. | During an 18-month period of study 41 hemodialyzed patients receiving /"desferrioxamine"/ (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of visual or auditory toxicity. Moreover, detailed ophthalmologic and audiologic studi... | desferrioxamine | {
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
} | hearing loss | {
"id": "301",
"normalized": [
{
"db_id": "D034381",
"db_name": "MESH"
}
],
"offsets": [
[
911,
923
]
],
"text": [
"hearing loss"
],
"type": "Disease"
} | [
{
"id": "288",
"normalized": [
{
"db_id": "D003676",
"db_name": "MESH"
}
],
"offsets": [
[
64,
79
]
],
"text": [
"desferrioxamine"
],
"type": "Chemical"
},
{
"id": "289",
"normalized": [
{
"db_id"... | [
{
"id": "285",
"normalized": [
{
"db_id": "D014786",
"db_name": "MESH"
},
{
"db_id": "D006311",
"db_name": "MESH"
}
],
"offsets": [
[
0,
28
]
],
"text": [
"Ocular and auditory toxicity"
],
"type... | Ocular and auditory toxicity in hemodialyzed patients receiving desferrioxamine. | During an 18-month period of study 41 hemodialyzed patients receiving desferrioxamine (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of visual or auditory toxicity. Moreover, detailed ophthalmologic and audiologic studies d... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"magnesium"/ induces disease /"Myasthenia gravis"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Myasthenia gravis"/ presenting as weakness after /"magnesium"/ administration.
- Abstract: We... | Yes | /"Myasthenia gravis"/ presenting as weakness after /"magnesium"/ administration. | We studied a patient with no prior history of neuromuscular disease who became virtually quadriplegic after parenteral /"magnesium"/ administration for preeclampsia. The serum /"magnesium"/ concentration was 3.0 mEq/L, which is usually well tolerated. The /"magnesium"/ was stopped and she recovered over a few days. Whi... | magnesium | {
"id": "361",
"normalized": [
{
"db_id": "D008274",
"db_name": "MESH"
}
],
"offsets": [
[
47,
56
]
],
"text": [
"magnesium"
],
"type": "Chemical"
} | Myasthenia gravis | {
"id": "360",
"normalized": [
{
"db_id": "D009157",
"db_name": "MESH"
}
],
"offsets": [
[
0,
17
]
],
"text": [
"Myasthenia gravis"
],
"type": "Disease"
} | [
{
"id": "361",
"normalized": [
{
"db_id": "D008274",
"db_name": "MESH"
}
],
"offsets": [
[
47,
56
]
],
"text": [
"magnesium"
],
"type": "Chemical"
},
{
"id": "364",
"normalized": [
{
"db_id": "D00... | [
{
"id": "360",
"normalized": [
{
"db_id": "D009157",
"db_name": "MESH"
}
],
"offsets": [
[
0,
17
]
],
"text": [
"Myasthenia gravis"
],
"type": "Disease"
},
{
"id": "362",
"normalized": [
{
"db_id"... | Myasthenia gravis presenting as weakness after magnesium administration. | We studied a patient with no prior history of neuromuscular disease who became virtually quadriplegic after parenteral magnesium administration for preeclampsia. The serum magnesium concentration was 3.0 mEq/L, which is usually well tolerated. The magnesium was stopped and she recovered over a few days. While she was w... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"acetylcholine"/ induces disease /"preeclampsia"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Myasthenia gravis presenting as weakness after magnesium administration.
- Abstract: We studied ... | No | Myasthenia gravis presenting as weakness after magnesium administration. | We studied a patient with no prior history of neuromuscular disease who became virtually quadriplegic after parenteral magnesium administration for /"preeclampsia"/. The serum magnesium concentration was 3.0 mEq/L, which is usually well tolerated. The magnesium was stopped and she recovered over a few days. While she w... | acetylcholine | {
"id": "369",
"normalized": [
{
"db_id": "D000109",
"db_name": "MESH"
}
],
"offsets": [
[
691,
704
]
],
"text": [
"acetylcholine"
],
"type": "Chemical"
} | preeclampsia | {
"id": "365",
"normalized": [
{
"db_id": "D011225",
"db_name": "MESH"
}
],
"offsets": [
[
221,
233
]
],
"text": [
"preeclampsia"
],
"type": "Disease"
} | [
{
"id": "361",
"normalized": [
{
"db_id": "D008274",
"db_name": "MESH"
}
],
"offsets": [
[
47,
56
]
],
"text": [
"magnesium"
],
"type": "Chemical"
},
{
"id": "364",
"normalized": [
{
"db_id": "D00... | [
{
"id": "360",
"normalized": [
{
"db_id": "D009157",
"db_name": "MESH"
}
],
"offsets": [
[
0,
17
]
],
"text": [
"Myasthenia gravis"
],
"type": "Disease"
},
{
"id": "362",
"normalized": [
{
"db_id"... | Myasthenia gravis presenting as weakness after magnesium administration. | We studied a patient with no prior history of neuromuscular disease who became virtually quadriplegic after parenteral magnesium administration for preeclampsia. The serum magnesium concentration was 3.0 mEq/L, which is usually well tolerated. The magnesium was stopped and she recovered over a few days. While she was w... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Chloroacetaldehyde"/ induces disease /"hemorrhagic cystitis"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Chloroacetaldehyde"/ and its contribution to urotoxicity during treatment with cy... | Yes | /"Chloroacetaldehyde"/ and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication. | Based on clinical data, indicating that /"chloroacetaldehyde"/ (/"CAA"/) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of /"CAA"/ in the development of /"hemorrhagic cystitis"/. The data demonstrate that /"CAA"/ after i.v. administration... | Chloroacetaldehyde | {
"id": "390",
"normalized": [
{
"db_id": "C004656",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Chloroacetaldehyde"
],
"type": "Chemical"
} | hemorrhagic cystitis | {
"id": "396",
"normalized": [
{
"db_id": "D006470",
"db_name": "MESH"
},
{
"db_id": "D003556",
"db_name": "MESH"
}
],
"offsets": [
[
375,
395
]
],
"text": [
"hemorrhagic cystitis"
],
"type": "Disease"
} | [
{
"id": "390",
"normalized": [
{
"db_id": "C004656",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Chloroacetaldehyde"
],
"type": "Chemical"
},
{
"id": "391",
"normalized": [
{
"db_i... | [
{
"id": "396",
"normalized": [
{
"db_id": "D006470",
"db_name": "MESH"
},
{
"db_id": "D003556",
"db_name": "MESH"
}
],
"offsets": [
[
375,
395
]
],
"text": [
"hemorrhagic cystitis"
],
"type": "D... | Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication. | Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of hemorrhagic cystitis. The data demonstrate that CAA after i.v. administration does not contribute... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Chloroacetaldehyde"/ induces disease /"cystitis"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Chloroacetaldehyde"/ and its contribution to urotoxicity during treatment with cyclophosphami... | Yes | /"Chloroacetaldehyde"/ and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication. | Based on clinical data, indicating that /"chloroacetaldehyde"/ (/"CAA"/) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of /"CAA"/ in the development of hemorrhagic /"cystitis"/. The data demonstrate that /"CAA"/ after i.v. administration... | Chloroacetaldehyde | {
"id": "390",
"normalized": [
{
"db_id": "C004656",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Chloroacetaldehyde"
],
"type": "Chemical"
} | cystitis | {
"id": "398",
"normalized": [
{
"db_id": "D003556",
"db_name": "MESH"
}
],
"offsets": [
[
387,
395
]
],
"text": [
"cystitis"
],
"type": "Disease"
} | [
{
"id": "390",
"normalized": [
{
"db_id": "C004656",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Chloroacetaldehyde"
],
"type": "Chemical"
},
{
"id": "391",
"normalized": [
{
"db_i... | [
{
"id": "396",
"normalized": [
{
"db_id": "D006470",
"db_name": "MESH"
},
{
"db_id": "D003556",
"db_name": "MESH"
}
],
"offsets": [
[
375,
395
]
],
"text": [
"hemorrhagic cystitis"
],
"type": "D... | Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication. | Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of hemorrhagic cystitis. The data demonstrate that CAA after i.v. administration does not contribute... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Chloroacetaldehyde"/ induces disease /"hemorrhagic"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Chloroacetaldehyde"/ and its contribution to urotoxicity during treatment with cyclophosph... | Yes | /"Chloroacetaldehyde"/ and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication. | Based on clinical data, indicating that /"chloroacetaldehyde"/ (/"CAA"/) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of /"CAA"/ in the development of /"hemorrhagic"/ cystitis. The data demonstrate that /"CAA"/ after i.v. administration... | Chloroacetaldehyde | {
"id": "390",
"normalized": [
{
"db_id": "C004656",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Chloroacetaldehyde"
],
"type": "Chemical"
} | hemorrhagic | {
"id": "397",
"normalized": [
{
"db_id": "D006470",
"db_name": "MESH"
}
],
"offsets": [
[
375,
386
]
],
"text": [
"hemorrhagic"
],
"type": "Disease"
} | [
{
"id": "390",
"normalized": [
{
"db_id": "C004656",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Chloroacetaldehyde"
],
"type": "Chemical"
},
{
"id": "391",
"normalized": [
{
"db_i... | [
{
"id": "396",
"normalized": [
{
"db_id": "D006470",
"db_name": "MESH"
},
{
"db_id": "D003556",
"db_name": "MESH"
}
],
"offsets": [
[
375,
395
]
],
"text": [
"hemorrhagic cystitis"
],
"type": "D... | Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication. | Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of hemorrhagic cystitis. The data demonstrate that CAA after i.v. administration does not contribute... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Chloroacetaldehyde"/ induces disease /"bladder damage"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Chloroacetaldehyde"/ and its contribution to urotoxicity during treatment with cyclopho... | No | /"Chloroacetaldehyde"/ and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication. | Based on clinical data, indicating that /"chloroacetaldehyde"/ (/"CAA"/) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of /"CAA"/ in the development of hemorrhagic cystitis. The data demonstrate that /"CAA"/ after i.v. administration doe... | Chloroacetaldehyde | {
"id": "390",
"normalized": [
{
"db_id": "C004656",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Chloroacetaldehyde"
],
"type": "Chemical"
} | bladder damage | {
"id": "400",
"normalized": [
{
"db_id": "D001745",
"db_name": "MESH"
}
],
"offsets": [
[
476,
490
]
],
"text": [
"bladder damage"
],
"type": "Disease"
} | [
{
"id": "390",
"normalized": [
{
"db_id": "C004656",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Chloroacetaldehyde"
],
"type": "Chemical"
},
{
"id": "391",
"normalized": [
{
"db_i... | [
{
"id": "396",
"normalized": [
{
"db_id": "D006470",
"db_name": "MESH"
},
{
"db_id": "D003556",
"db_name": "MESH"
}
],
"offsets": [
[
375,
395
]
],
"text": [
"hemorrhagic cystitis"
],
"type": "D... | Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication. | Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of hemorrhagic cystitis. The data demonstrate that CAA after i.v. administration does not contribute... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"ifosfamide"/ induces disease /"bladder damage"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ... | No | Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or /"ifosfamide"/. An experimental study/short communication. | Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of hemorrhagic cystitis. The data demonstrate that CAA after i.v. administration does not contribute... | ifosfamide | {
"id": "392",
"normalized": [
{
"db_id": "D007069",
"db_name": "MESH"
}
],
"offsets": [
[
97,
107
]
],
"text": [
"ifosfamide"
],
"type": "Chemical"
} | bladder damage | {
"id": "400",
"normalized": [
{
"db_id": "D001745",
"db_name": "MESH"
}
],
"offsets": [
[
476,
490
]
],
"text": [
"bladder damage"
],
"type": "Disease"
} | [
{
"id": "390",
"normalized": [
{
"db_id": "C004656",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Chloroacetaldehyde"
],
"type": "Chemical"
},
{
"id": "391",
"normalized": [
{
"db_i... | [
{
"id": "396",
"normalized": [
{
"db_id": "D006470",
"db_name": "MESH"
},
{
"db_id": "D003556",
"db_name": "MESH"
}
],
"offsets": [
[
375,
395
]
],
"text": [
"hemorrhagic cystitis"
],
"type": "D... | Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication. | Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of hemorrhagic cystitis. The data demonstrate that CAA after i.v. administration does not contribute... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"mesna"/ induces disease /"hemorrhagic"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfami... | No | Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication. | Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of /"hemorrhagic"/ cystitis. The data demonstrate that CAA after i.v. administration does not contri... | mesna | {
"id": "402",
"normalized": [
{
"db_id": "D015080",
"db_name": "MESH"
}
],
"offsets": [
[
614,
619
]
],
"text": [
"mesna"
],
"type": "Chemical"
} | hemorrhagic | {
"id": "397",
"normalized": [
{
"db_id": "D006470",
"db_name": "MESH"
}
],
"offsets": [
[
375,
386
]
],
"text": [
"hemorrhagic"
],
"type": "Disease"
} | [
{
"id": "390",
"normalized": [
{
"db_id": "C004656",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Chloroacetaldehyde"
],
"type": "Chemical"
},
{
"id": "391",
"normalized": [
{
"db_i... | [
{
"id": "396",
"normalized": [
{
"db_id": "D006470",
"db_name": "MESH"
},
{
"db_id": "D003556",
"db_name": "MESH"
}
],
"offsets": [
[
375,
395
]
],
"text": [
"hemorrhagic cystitis"
],
"type": "D... | Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication. | Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of hemorrhagic cystitis. The data demonstrate that CAA after i.v. administration does not contribute... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"nitroglycerin"/ induces disease /"migraine"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Source of pain and primitive dysfunction in /"migraine"/: an identical site?
- Abstract: Twenty comm... | Yes | Source of pain and primitive dysfunction in /"migraine"/: an identical site? | Twenty common /"migraine"/ patients received a one sided frontotemporal application of /"nitroglycerin"/ (10 patients) or placebo ointment (10 patients) in a double blind study. Early onset /"migraine"/ attacks were induced by /"nitroglycerin"/ in seven out of 10 patients versus no patient in the placebo group. Subsequ... | nitroglycerin | {
"id": "433",
"normalized": [
{
"db_id": "D005996",
"db_name": "MESH"
}
],
"offsets": [
[
156,
169
]
],
"text": [
"nitroglycerin"
],
"type": "Chemical"
} | migraine | {
"id": "431",
"normalized": [
{
"db_id": "D008881",
"db_name": "MESH"
}
],
"offsets": [
[
44,
52
]
],
"text": [
"migraine"
],
"type": "Disease"
} | [
{
"id": "433",
"normalized": [
{
"db_id": "D005996",
"db_name": "MESH"
}
],
"offsets": [
[
156,
169
]
],
"text": [
"nitroglycerin"
],
"type": "Chemical"
},
{
"id": "435",
"normalized": [
{
"db_id"... | [
{
"id": "430",
"normalized": [
{
"db_id": "D010146",
"db_name": "MESH"
}
],
"offsets": [
[
10,
14
]
],
"text": [
"pain"
],
"type": "Disease"
},
{
"id": "431",
"normalized": [
{
"db_id": "D008881",... | Source of pain and primitive dysfunction in migraine: an identical site? | Twenty common migraine patients received a one sided frontotemporal application of nitroglycerin (10 patients) or placebo ointment (10 patients) in a double blind study. Early onset migraine attacks were induced by nitroglycerin in seven out of 10 patients versus no patient in the placebo group. Subsequently 20 migrain... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"nitroglycerin"/ induces disease /"pain"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Source of /"pain"/ and primitive dysfunction in migraine: an identical site?
- Abstract: Twenty common m... | No | Source of /"pain"/ and primitive dysfunction in migraine: an identical site? | Twenty common migraine patients received a one sided frontotemporal application of /"nitroglycerin"/ (10 patients) or placebo ointment (10 patients) in a double blind study. Early onset migraine attacks were induced by /"nitroglycerin"/ in seven out of 10 patients versus no patient in the placebo group. Subsequently 20... | nitroglycerin | {
"id": "433",
"normalized": [
{
"db_id": "D005996",
"db_name": "MESH"
}
],
"offsets": [
[
156,
169
]
],
"text": [
"nitroglycerin"
],
"type": "Chemical"
} | pain | {
"id": "430",
"normalized": [
{
"db_id": "D010146",
"db_name": "MESH"
}
],
"offsets": [
[
10,
14
]
],
"text": [
"pain"
],
"type": "Disease"
} | [
{
"id": "433",
"normalized": [
{
"db_id": "D005996",
"db_name": "MESH"
}
],
"offsets": [
[
156,
169
]
],
"text": [
"nitroglycerin"
],
"type": "Chemical"
},
{
"id": "435",
"normalized": [
{
"db_id"... | [
{
"id": "430",
"normalized": [
{
"db_id": "D010146",
"db_name": "MESH"
}
],
"offsets": [
[
10,
14
]
],
"text": [
"pain"
],
"type": "Disease"
},
{
"id": "431",
"normalized": [
{
"db_id": "D008881",... | Source of pain and primitive dysfunction in migraine: an identical site? | Twenty common migraine patients received a one sided frontotemporal application of nitroglycerin (10 patients) or placebo ointment (10 patients) in a double blind study. Early onset migraine attacks were induced by nitroglycerin in seven out of 10 patients versus no patient in the placebo group. Subsequently 20 migrain... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Clotiazepam"/ induces disease /"hepatitis"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Clotiazepam"/-induced acute /"hepatitis"/.
- Abstract: We report the case of a patient who develope... | Yes | /"Clotiazepam"/-induced acute /"hepatitis"/. | We report the case of a patient who developed acute /"hepatitis"/ with extensive hepatocellular necrosis, 7 months after the onset of administration of /"clotiazepam"/, a thienodiazepine derivative. /"Clotiazepam"/ withdrawal was followed by prompt recovery. The administration of several benzodiazepines, chemically rel... | Clotiazepam | {
"id": "479",
"normalized": [
{
"db_id": "C084599",
"db_name": "MESH"
}
],
"offsets": [
[
0,
11
]
],
"text": [
"Clotiazepam"
],
"type": "Chemical"
} | hepatitis | {
"id": "480",
"normalized": [
{
"db_id": "D056486",
"db_name": "MESH"
}
],
"offsets": [
[
26,
35
]
],
"text": [
"hepatitis"
],
"type": "Disease"
} | [
{
"id": "479",
"normalized": [
{
"db_id": "C084599",
"db_name": "MESH"
}
],
"offsets": [
[
0,
11
]
],
"text": [
"Clotiazepam"
],
"type": "Chemical"
},
{
"id": "483",
"normalized": [
{
"db_id": "C0... | [
{
"id": "480",
"normalized": [
{
"db_id": "D056486",
"db_name": "MESH"
}
],
"offsets": [
[
26,
35
]
],
"text": [
"hepatitis"
],
"type": "Disease"
},
{
"id": "481",
"normalized": [
{
"db_id": "D056... | Clotiazepam-induced acute hepatitis. | We report the case of a patient who developed acute hepatitis with extensive hepatocellular necrosis, 7 months after the onset of administration of clotiazepam, a thienodiazepine derivative. Clotiazepam withdrawal was followed by prompt recovery. The administration of several benzodiazepines, chemically related to clot... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"benzodiazepines"/ induces disease /"extensive hepatocellular necrosis"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Clotiazepam-induced acute hepatitis.
- Abstract: We report the case of a ... | No | Clotiazepam-induced acute hepatitis. | We report the case of a patient who developed acute hepatitis with /"extensive hepatocellular necrosis"/, 7 months after the onset of administration of clotiazepam, a thienodiazepine derivative. Clotiazepam withdrawal was followed by prompt recovery. The administration of several /"benzodiazepines"/, chemically related... | benzodiazepines | {
"id": "486",
"normalized": [
{
"db_id": "D001569",
"db_name": "MESH"
}
],
"offsets": [
[
314,
329
]
],
"text": [
"benzodiazepines"
],
"type": "Chemical"
} | extensive hepatocellular necrosis | {
"id": "482",
"normalized": [
{
"db_id": "D047508",
"db_name": "MESH"
}
],
"offsets": [
[
104,
137
]
],
"text": [
"extensive hepatocellular necrosis"
],
"type": "Disease"
} | [
{
"id": "479",
"normalized": [
{
"db_id": "C084599",
"db_name": "MESH"
}
],
"offsets": [
[
0,
11
]
],
"text": [
"Clotiazepam"
],
"type": "Chemical"
},
{
"id": "483",
"normalized": [
{
"db_id": "C0... | [
{
"id": "480",
"normalized": [
{
"db_id": "D056486",
"db_name": "MESH"
}
],
"offsets": [
[
26,
35
]
],
"text": [
"hepatitis"
],
"type": "Disease"
},
{
"id": "481",
"normalized": [
{
"db_id": "D056... | Clotiazepam-induced acute hepatitis. | We report the case of a patient who developed acute hepatitis with extensive hepatocellular necrosis, 7 months after the onset of administration of clotiazepam, a thienodiazepine derivative. Clotiazepam withdrawal was followed by prompt recovery. The administration of several benzodiazepines, chemically related to clot... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"ketoconazole"/ induces disease /"hypertension"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Arterial /"hypertension"/ as a complication of prolonged /"ketoconazole"/ treatment.
- Abstract: ... | Yes | Arterial /"hypertension"/ as a complication of prolonged /"ketoconazole"/ treatment. | Two of 14 patients with Cushing's syndrome treated on a long-term basis with /"ketoconazole"/ developed sustained /"hypertension"/. In both cases normal plasma and urinary free cortisol levels had been achieved following /"ketoconazole"/ therapy, yet continuous blood pressure monitoring demonstrated /"hypertension"/ 31... | ketoconazole | {
"id": "528",
"normalized": [
{
"db_id": "D007654",
"db_name": "MESH"
}
],
"offsets": [
[
53,
65
]
],
"text": [
"ketoconazole"
],
"type": "Chemical"
} | hypertension | {
"id": "527",
"normalized": [
{
"db_id": "D006973",
"db_name": "MESH"
}
],
"offsets": [
[
9,
21
]
],
"text": [
"hypertension"
],
"type": "Disease"
} | [
{
"id": "528",
"normalized": [
{
"db_id": "D007654",
"db_name": "MESH"
}
],
"offsets": [
[
53,
65
]
],
"text": [
"ketoconazole"
],
"type": "Chemical"
},
{
"id": "530",
"normalized": [
{
"db_id": "... | [
{
"id": "527",
"normalized": [
{
"db_id": "D006973",
"db_name": "MESH"
}
],
"offsets": [
[
9,
21
]
],
"text": [
"hypertension"
],
"type": "Disease"
},
{
"id": "529",
"normalized": [
{
"db_id": "D0... | Arterial hypertension as a complication of prolonged ketoconazole treatment. | Two of 14 patients with Cushing's syndrome treated on a long-term basis with ketoconazole developed sustained hypertension. In both cases normal plasma and urinary free cortisol levels had been achieved following ketoconazole therapy, yet continuous blood pressure monitoring demonstrated hypertension 31 (patient 1) and... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"deoxycorticosterone"/ induces disease /"hypertension"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Arterial /"hypertension"/ as a complication of prolonged ketoconazole treatment.
- Abstrac... | No | Arterial /"hypertension"/ as a complication of prolonged ketoconazole treatment. | Two of 14 patients with Cushing's syndrome treated on a long-term basis with ketoconazole developed sustained /"hypertension"/. In both cases normal plasma and urinary free cortisol levels had been achieved following ketoconazole therapy, yet continuous blood pressure monitoring demonstrated /"hypertension"/ 31 (patien... | deoxycorticosterone | {
"id": "535",
"normalized": [
{
"db_id": "D003900",
"db_name": "MESH"
}
],
"offsets": [
[
467,
486
]
],
"text": [
"deoxycorticosterone"
],
"type": "Chemical"
} | hypertension | {
"id": "527",
"normalized": [
{
"db_id": "D006973",
"db_name": "MESH"
}
],
"offsets": [
[
9,
21
]
],
"text": [
"hypertension"
],
"type": "Disease"
} | [
{
"id": "528",
"normalized": [
{
"db_id": "D007654",
"db_name": "MESH"
}
],
"offsets": [
[
53,
65
]
],
"text": [
"ketoconazole"
],
"type": "Chemical"
},
{
"id": "530",
"normalized": [
{
"db_id": "... | [
{
"id": "527",
"normalized": [
{
"db_id": "D006973",
"db_name": "MESH"
}
],
"offsets": [
[
9,
21
]
],
"text": [
"hypertension"
],
"type": "Disease"
},
{
"id": "529",
"normalized": [
{
"db_id": "D0... | Arterial hypertension as a complication of prolonged ketoconazole treatment. | Two of 14 patients with Cushing's syndrome treated on a long-term basis with ketoconazole developed sustained hypertension. In both cases normal plasma and urinary free cortisol levels had been achieved following ketoconazole therapy, yet continuous blood pressure monitoring demonstrated hypertension 31 (patient 1) and... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"tranexamic acid"/ induces disease /"intravascular coagulation"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Effects of an inhibitor of angiotensin converting enzyme (Captopril) on pulmonary... | Yes | Effects of an inhibitor of angiotensin converting enzyme (Captopril) on pulmonary and renal insufficiency due to /"intravascular coagulation"/ in the rat. | Induction of /"intravascular coagulation"/ and inhibition of fibrinolysis by injection of thrombin and /"tranexamic acid"/ (/"AMCA"/) in the rat gives rise to pulmonary and renal insufficiency resembling that occurring after trauma or sepsis in man. Injection of Captopril (1 mg/kg), an inhibitor of angiotensin converti... | tranexamic acid | {
"id": "568",
"normalized": [
{
"db_id": "D014148",
"db_name": "MESH"
}
],
"offsets": [
[
250,
265
]
],
"text": [
"tranexamic acid"
],
"type": "Chemical"
} | intravascular coagulation | {
"id": "566",
"normalized": [
{
"db_id": "D004211",
"db_name": "MESH"
}
],
"offsets": [
[
113,
138
]
],
"text": [
"intravascular coagulation"
],
"type": "Disease"
} | [
{
"id": "561",
"normalized": [
{
"db_id": "D000809",
"db_name": "MESH"
}
],
"offsets": [
[
27,
38
]
],
"text": [
"angiotensin"
],
"type": "Chemical"
},
{
"id": "562",
"normalized": [
{
"db_id": "D... | [
{
"id": "563",
"normalized": [
{
"db_id": "D011665",
"db_name": "MESH"
},
{
"db_id": "D051437",
"db_name": "MESH"
}
],
"offsets": [
[
72,
105
]
],
"text": [
"pulmonary and renal insufficiency"
],
... | Effects of an inhibitor of angiotensin converting enzyme (Captopril) on pulmonary and renal insufficiency due to intravascular coagulation in the rat. | Induction of intravascular coagulation and inhibition of fibrinolysis by injection of thrombin and tranexamic acid (AMCA) in the rat gives rise to pulmonary and renal insufficiency resembling that occurring after trauma or sepsis in man. Injection of Captopril (1 mg/kg), an inhibitor of angiotensin converting enzyme (A... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"prostacyclin"/ induces disease /"pulmonary and renal insufficiency"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Effects of an inhibitor of angiotensin converting enzyme (Captopril) on /"pu... | No | Effects of an inhibitor of angiotensin converting enzyme (Captopril) on /"pulmonary and renal insufficiency"/ due to intravascular coagulation in the rat. | Induction of intravascular coagulation and inhibition of fibrinolysis by injection of thrombin and tranexamic acid (AMCA) in the rat gives rise to /"pulmonary and renal insufficiency"/ resembling that occurring after trauma or sepsis in man. Injection of Captopril (1 mg/kg), an inhibitor of angiotensin converting enzym... | prostacyclin | {
"id": "587",
"normalized": [
{
"db_id": "D011464",
"db_name": "MESH"
}
],
"offsets": [
[
1173,
1185
]
],
"text": [
"prostacyclin"
],
"type": "Chemical"
} | pulmonary and renal insufficiency | {
"id": "563",
"normalized": [
{
"db_id": "D011665",
"db_name": "MESH"
},
{
"db_id": "D051437",
"db_name": "MESH"
}
],
"offsets": [
[
72,
105
]
],
"text": [
"pulmonary and renal insufficiency"
],
"type": "Disease"
} | [
{
"id": "561",
"normalized": [
{
"db_id": "D000809",
"db_name": "MESH"
}
],
"offsets": [
[
27,
38
]
],
"text": [
"angiotensin"
],
"type": "Chemical"
},
{
"id": "562",
"normalized": [
{
"db_id": "D... | [
{
"id": "563",
"normalized": [
{
"db_id": "D011665",
"db_name": "MESH"
},
{
"db_id": "D051437",
"db_name": "MESH"
}
],
"offsets": [
[
72,
105
]
],
"text": [
"pulmonary and renal insufficiency"
],
... | Effects of an inhibitor of angiotensin converting enzyme (Captopril) on pulmonary and renal insufficiency due to intravascular coagulation in the rat. | Induction of intravascular coagulation and inhibition of fibrinolysis by injection of thrombin and tranexamic acid (AMCA) in the rat gives rise to pulmonary and renal insufficiency resembling that occurring after trauma or sepsis in man. Injection of Captopril (1 mg/kg), an inhibitor of angiotensin converting enzyme (A... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"nitroprusside"/ induces disease /"hypotension"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: A randomized comparison of labetalol and /"nitroprusside"/ for induced /"hypotension"/.
- Abstrac... | Yes | A randomized comparison of labetalol and /"nitroprusside"/ for induced /"hypotension"/. | In a randomized study, labetalol-induced /"hypotension"/ and /"nitroprusside"/-induced /"hypotension"/ were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced /"reductions in mean arterial blood pr... | nitroprusside | {
"id": "601",
"normalized": [
{
"db_id": "D009599",
"db_name": "MESH"
}
],
"offsets": [
[
41,
54
]
],
"text": [
"nitroprusside"
],
"type": "Chemical"
} | hypotension | {
"id": "602",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
67,
78
]
],
"text": [
"hypotension"
],
"type": "Disease"
} | [
{
"id": "600",
"normalized": [
{
"db_id": "D007741",
"db_name": "MESH"
}
],
"offsets": [
[
27,
36
]
],
"text": [
"labetalol"
],
"type": "Chemical"
},
{
"id": "601",
"normalized": [
{
"db_id": "D00... | [
{
"id": "602",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
67,
78
]
],
"text": [
"hypotension"
],
"type": "Disease"
},
{
"id": "604",
"normalized": [
{
"db_id": "D0... | A randomized comparison of labetalol and nitroprusside for induced hypotension. | In a randomized study, labetalol-induced hypotension and nitroprusside-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced reductions in mean arterial blood pressure (BP) (5... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"nitroprusside"/ induces disease /"increase in heart rate and cardiac output"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: A randomized comparison of labetalol and /"nitroprusside"/ for indu... | Yes | A randomized comparison of labetalol and /"nitroprusside"/ for induced hypotension. | In a randomized study, labetalol-induced hypotension and /"nitroprusside"/-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced reductions in mean arterial blood pressure (BP... | nitroprusside | {
"id": "601",
"normalized": [
{
"db_id": "D009599",
"db_name": "MESH"
}
],
"offsets": [
[
41,
54
]
],
"text": [
"nitroprusside"
],
"type": "Chemical"
} | increase in heart rate and cardiac output | {
"id": "608",
"normalized": [
{
"db_id": "D016534",
"db_name": "MESH"
}
],
"offsets": [
[
491,
532
]
],
"text": [
"increase in heart rate and cardiac output"
],
"type": "Disease"
} | [
{
"id": "600",
"normalized": [
{
"db_id": "D007741",
"db_name": "MESH"
}
],
"offsets": [
[
27,
36
]
],
"text": [
"labetalol"
],
"type": "Chemical"
},
{
"id": "601",
"normalized": [
{
"db_id": "D00... | [
{
"id": "602",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
67,
78
]
],
"text": [
"hypotension"
],
"type": "Disease"
},
{
"id": "604",
"normalized": [
{
"db_id": "D0... | A randomized comparison of labetalol and nitroprusside for induced hypotension. | In a randomized study, labetalol-induced hypotension and nitroprusside-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced reductions in mean arterial blood pressure (BP) (5... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"labetalol"/ induces disease /"hypotension"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: A randomized comparison of /"labetalol"/ and nitroprusside for induced /"hypotension"/.
- Abstract: I... | Yes | A randomized comparison of /"labetalol"/ and nitroprusside for induced /"hypotension"/. | In a randomized study, /"labetalol"/-induced /"hypotension"/ and nitroprusside-induced /"hypotension"/ were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced /"reductions in mean arterial blood pr... | labetalol | {
"id": "600",
"normalized": [
{
"db_id": "D007741",
"db_name": "MESH"
}
],
"offsets": [
[
27,
36
]
],
"text": [
"labetalol"
],
"type": "Chemical"
} | hypotension | {
"id": "602",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
67,
78
]
],
"text": [
"hypotension"
],
"type": "Disease"
} | [
{
"id": "600",
"normalized": [
{
"db_id": "D007741",
"db_name": "MESH"
}
],
"offsets": [
[
27,
36
]
],
"text": [
"labetalol"
],
"type": "Chemical"
},
{
"id": "601",
"normalized": [
{
"db_id": "D00... | [
{
"id": "602",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
67,
78
]
],
"text": [
"hypotension"
],
"type": "Disease"
},
{
"id": "604",
"normalized": [
{
"db_id": "D0... | A randomized comparison of labetalol and nitroprusside for induced hypotension. | In a randomized study, labetalol-induced hypotension and nitroprusside-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced reductions in mean arterial blood pressure (BP) (5... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"labetalol"/ induces disease /"increase in heart rate and cardiac output"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: A randomized comparison of /"labetalol"/ and nitroprusside for induced ... | No | A randomized comparison of /"labetalol"/ and nitroprusside for induced hypotension. | In a randomized study, /"labetalol"/-induced hypotension and nitroprusside-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced reductions in mean arterial blood pressure (BP... | labetalol | {
"id": "600",
"normalized": [
{
"db_id": "D007741",
"db_name": "MESH"
}
],
"offsets": [
[
27,
36
]
],
"text": [
"labetalol"
],
"type": "Chemical"
} | increase in heart rate and cardiac output | {
"id": "608",
"normalized": [
{
"db_id": "D016534",
"db_name": "MESH"
}
],
"offsets": [
[
491,
532
]
],
"text": [
"increase in heart rate and cardiac output"
],
"type": "Disease"
} | [
{
"id": "600",
"normalized": [
{
"db_id": "D007741",
"db_name": "MESH"
}
],
"offsets": [
[
27,
36
]
],
"text": [
"labetalol"
],
"type": "Chemical"
},
{
"id": "601",
"normalized": [
{
"db_id": "D00... | [
{
"id": "602",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
67,
78
]
],
"text": [
"hypotension"
],
"type": "Disease"
},
{
"id": "604",
"normalized": [
{
"db_id": "D0... | A randomized comparison of labetalol and nitroprusside for induced hypotension. | In a randomized study, labetalol-induced hypotension and nitroprusside-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced reductions in mean arterial blood pressure (BP) (5... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"PO2"/ induces disease /"hypertension"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: A randomized comparison of labetalol and nitroprusside for induced hypotension.
- Abstract: In a randomize... | No | A randomized comparison of labetalol and nitroprusside for induced hypotension. | In a randomized study, labetalol-induced hypotension and nitroprusside-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced reductions in mean arterial blood pressure (BP) (5... | PO2 | {
"id": "612",
"normalized": [
{
"db_id": "C093415",
"db_name": "MESH"
}
],
"offsets": [
[
707,
710
]
],
"text": [
"PO2"
],
"type": "Chemical"
} | hypertension | {
"id": "609",
"normalized": [
{
"db_id": "D006973",
"db_name": "MESH"
}
],
"offsets": [
[
542,
554
]
],
"text": [
"hypertension"
],
"type": "Disease"
} | [
{
"id": "600",
"normalized": [
{
"db_id": "D007741",
"db_name": "MESH"
}
],
"offsets": [
[
27,
36
]
],
"text": [
"labetalol"
],
"type": "Chemical"
},
{
"id": "601",
"normalized": [
{
"db_id": "D00... | [
{
"id": "602",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
67,
78
]
],
"text": [
"hypotension"
],
"type": "Disease"
},
{
"id": "604",
"normalized": [
{
"db_id": "D0... | A randomized comparison of labetalol and nitroprusside for induced hypotension. | In a randomized study, labetalol-induced hypotension and nitroprusside-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced reductions in mean arterial blood pressure (BP) (5... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"labetalol"/ induces disease /"hypertension"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: A randomized comparison of /"labetalol"/ and nitroprusside for induced hypotension.
- Abstract: In a... | No | A randomized comparison of /"labetalol"/ and nitroprusside for induced hypotension. | In a randomized study, /"labetalol"/-induced hypotension and nitroprusside-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced reductions in mean arterial blood pressure (BP... | labetalol | {
"id": "600",
"normalized": [
{
"db_id": "D007741",
"db_name": "MESH"
}
],
"offsets": [
[
27,
36
]
],
"text": [
"labetalol"
],
"type": "Chemical"
} | hypertension | {
"id": "609",
"normalized": [
{
"db_id": "D006973",
"db_name": "MESH"
}
],
"offsets": [
[
542,
554
]
],
"text": [
"hypertension"
],
"type": "Disease"
} | [
{
"id": "600",
"normalized": [
{
"db_id": "D007741",
"db_name": "MESH"
}
],
"offsets": [
[
27,
36
]
],
"text": [
"labetalol"
],
"type": "Chemical"
},
{
"id": "601",
"normalized": [
{
"db_id": "D00... | [
{
"id": "602",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
67,
78
]
],
"text": [
"hypotension"
],
"type": "Disease"
},
{
"id": "604",
"normalized": [
{
"db_id": "D0... | A randomized comparison of labetalol and nitroprusside for induced hypotension. | In a randomized study, labetalol-induced hypotension and nitroprusside-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures. Each patient was subjected to an identical anesthetic protocol and similar drug-induced reductions in mean arterial blood pressure (BP) (5... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"hexafluorodiethyl ether"/ induces disease /"seizures"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Chronic carbamazepine treatment in the rat: efficacy, toxicity, and effect on plasma and t... | Yes | Chronic carbamazepine treatment in the rat: efficacy, toxicity, and effect on plasma and tissue folate concentrations. | Folate depletion has often been a problem in chronic antiepileptic drug (AED) therapy. Carbamazepine (CBZ), a commonly used AED, has been implicated in some clinical studies. A rat model was developed to examine the effects of chronic CBZ treatment on folate concentrations in the rat. In the course of developing this m... | hexafluorodiethyl ether | {
"id": "666",
"normalized": [
{
"db_id": "D005481",
"db_name": "MESH"
}
],
"offsets": [
[
621,
644
]
],
"text": [
"hexafluorodiethyl ether"
],
"type": "Chemical"
} | seizures | {
"id": "663",
"normalized": [
{
"db_id": "D012640",
"db_name": "MESH"
}
],
"offsets": [
[
565,
573
]
],
"text": [
"seizures"
],
"type": "Disease"
} | [
{
"id": "654",
"normalized": [
{
"db_id": "D002220",
"db_name": "MESH"
}
],
"offsets": [
[
8,
21
]
],
"text": [
"carbamazepine"
],
"type": "Chemical"
},
{
"id": "656",
"normalized": [
{
"db_id": "... | [
{
"id": "655",
"normalized": [
{
"db_id": "D064420",
"db_name": "MESH"
}
],
"offsets": [
[
54,
62
]
],
"text": [
"toxicity"
],
"type": "Disease"
},
{
"id": "663",
"normalized": [
{
"db_id": "D0126... | Chronic carbamazepine treatment in the rat: efficacy, toxicity, and effect on plasma and tissue folate concentrations. | Folate depletion has often been a problem in chronic antiepileptic drug (AED) therapy. Carbamazepine (CBZ), a commonly used AED, has been implicated in some clinical studies. A rat model was developed to examine the effects of chronic CBZ treatment on folate concentrations in the rat. In the course of developing this m... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"folate"/ induces disease /"weight gain"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Chronic carbamazepine treatment in the rat: efficacy, toxicity, and effect on plasma and tissue /"folate... | No | Chronic carbamazepine treatment in the rat: efficacy, toxicity, and effect on plasma and tissue /"folate"/ concentrations. | /"Folate"/ depletion has often been a problem in chronic antiepileptic drug (AED) therapy. Carbamazepine (CBZ), a commonly used AED, has been implicated in some clinical studies. A rat model was developed to examine the effects of chronic CBZ treatment on /"folate"/ concentrations in the rat. In the course of developin... | folate | {
"id": "656",
"normalized": [
{
"db_id": "D005492",
"db_name": "MESH"
}
],
"offsets": [
[
96,
102
]
],
"text": [
"folate"
],
"type": "Chemical"
} | weight gain | {
"id": "664",
"normalized": [
{
"db_id": "D015430",
"db_name": "MESH"
}
],
"offsets": [
[
588,
599
]
],
"text": [
"weight gain"
],
"type": "Disease"
} | [
{
"id": "654",
"normalized": [
{
"db_id": "D002220",
"db_name": "MESH"
}
],
"offsets": [
[
8,
21
]
],
"text": [
"carbamazepine"
],
"type": "Chemical"
},
{
"id": "656",
"normalized": [
{
"db_id": "... | [
{
"id": "655",
"normalized": [
{
"db_id": "D064420",
"db_name": "MESH"
}
],
"offsets": [
[
54,
62
]
],
"text": [
"toxicity"
],
"type": "Disease"
},
{
"id": "663",
"normalized": [
{
"db_id": "D0126... | Chronic carbamazepine treatment in the rat: efficacy, toxicity, and effect on plasma and tissue folate concentrations. | Folate depletion has often been a problem in chronic antiepileptic drug (AED) therapy. Carbamazepine (CBZ), a commonly used AED, has been implicated in some clinical studies. A rat model was developed to examine the effects of chronic CBZ treatment on folate concentrations in the rat. In the course of developing this m... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"nitroglycerin"/ induces disease /"hypotension"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs.
- Abstract: In six c... | Yes | Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs. | In six conscious, trained dogs, maintained on a normal sodium intake of 2 to 4 mEq/kg/day, sympathetic activity was assessed as the release rate of norepinephrine and epinephrine during 15-minute i.v. infusions of human alpha-atrial natriuretic factor. Mean arterial pressure (as a percentage of control +/- SEM) during ... | nitroglycerin | {
"id": "700",
"normalized": [
{
"db_id": "D005996",
"db_name": "MESH"
}
],
"offsets": [
[
772,
785
]
],
"text": [
"nitroglycerin"
],
"type": "Chemical"
} | hypotension | {
"id": "698",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
734,
745
]
],
"text": [
"hypotension"
],
"type": "Disease"
} | [
{
"id": "693",
"normalized": [
{
"db_id": "D012964",
"db_name": "MESH"
}
],
"offsets": [
[
132,
138
]
],
"text": [
"sodium"
],
"type": "Chemical"
},
{
"id": "694",
"normalized": [
{
"db_id": "D009... | [
{
"id": "696",
"normalized": [
{
"db_id": "D013610",
"db_name": "MESH"
}
],
"offsets": [
[
588,
599
]
],
"text": [
"tachycardia"
],
"type": "Disease"
},
{
"id": "698",
"normalized": [
{
"db_id": "... | Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs. | In six conscious, trained dogs, maintained on a normal sodium intake of 2 to 4 mEq/kg/day, sympathetic activity was assessed as the release rate of norepinephrine and epinephrine during 15-minute i.v. infusions of human alpha-atrial natriuretic factor. Mean arterial pressure (as a percentage of control +/- SEM) during ... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"hydralazine"/ induces disease /"hypotension"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs.
- Abstract: In six con... | Yes | Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs. | In six conscious, trained dogs, maintained on a normal sodium intake of 2 to 4 mEq/kg/day, sympathetic activity was assessed as the release rate of norepinephrine and epinephrine during 15-minute i.v. infusions of human alpha-atrial natriuretic factor. Mean arterial pressure (as a percentage of control +/- SEM) during ... | hydralazine | {
"id": "699",
"normalized": [
{
"db_id": "D006830",
"db_name": "MESH"
}
],
"offsets": [
[
757,
768
]
],
"text": [
"hydralazine"
],
"type": "Chemical"
} | hypotension | {
"id": "698",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
734,
745
]
],
"text": [
"hypotension"
],
"type": "Disease"
} | [
{
"id": "693",
"normalized": [
{
"db_id": "D012964",
"db_name": "MESH"
}
],
"offsets": [
[
132,
138
]
],
"text": [
"sodium"
],
"type": "Chemical"
},
{
"id": "694",
"normalized": [
{
"db_id": "D009... | [
{
"id": "696",
"normalized": [
{
"db_id": "D013610",
"db_name": "MESH"
}
],
"offsets": [
[
588,
599
]
],
"text": [
"tachycardia"
],
"type": "Disease"
},
{
"id": "698",
"normalized": [
{
"db_id": "... | Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs. | In six conscious, trained dogs, maintained on a normal sodium intake of 2 to 4 mEq/kg/day, sympathetic activity was assessed as the release rate of norepinephrine and epinephrine during 15-minute i.v. infusions of human alpha-atrial natriuretic factor. Mean arterial pressure (as a percentage of control +/- SEM) during ... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"epinephrine"/ induces disease /"tachycardia"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs.
- Abstract: In six con... | No | Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs. | In six conscious, trained dogs, maintained on a normal sodium intake of 2 to 4 mEq/kg/day, sympathetic activity was assessed as the release rate of norepinephrine and /"epinephrine"/ during 15-minute i.v. infusions of human alpha-atrial natriuretic factor. Mean arterial pressure (as a percentage of control +/- SEM) dur... | epinephrine | {
"id": "695",
"normalized": [
{
"db_id": "D004837",
"db_name": "MESH"
}
],
"offsets": [
[
244,
255
]
],
"text": [
"epinephrine"
],
"type": "Chemical"
} | tachycardia | {
"id": "696",
"normalized": [
{
"db_id": "D013610",
"db_name": "MESH"
}
],
"offsets": [
[
588,
599
]
],
"text": [
"tachycardia"
],
"type": "Disease"
} | [
{
"id": "693",
"normalized": [
{
"db_id": "D012964",
"db_name": "MESH"
}
],
"offsets": [
[
132,
138
]
],
"text": [
"sodium"
],
"type": "Chemical"
},
{
"id": "694",
"normalized": [
{
"db_id": "D009... | [
{
"id": "696",
"normalized": [
{
"db_id": "D013610",
"db_name": "MESH"
}
],
"offsets": [
[
588,
599
]
],
"text": [
"tachycardia"
],
"type": "Disease"
},
{
"id": "698",
"normalized": [
{
"db_id": "... | Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs. | In six conscious, trained dogs, maintained on a normal sodium intake of 2 to 4 mEq/kg/day, sympathetic activity was assessed as the release rate of norepinephrine and epinephrine during 15-minute i.v. infusions of human alpha-atrial natriuretic factor. Mean arterial pressure (as a percentage of control +/- SEM) during ... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"hydralazine"/ induces disease /"tachycardia"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs.
- Abstract: In six con... | No | Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs. | In six conscious, trained dogs, maintained on a normal sodium intake of 2 to 4 mEq/kg/day, sympathetic activity was assessed as the release rate of norepinephrine and epinephrine during 15-minute i.v. infusions of human alpha-atrial natriuretic factor. Mean arterial pressure (as a percentage of control +/- SEM) during ... | hydralazine | {
"id": "699",
"normalized": [
{
"db_id": "D006830",
"db_name": "MESH"
}
],
"offsets": [
[
757,
768
]
],
"text": [
"hydralazine"
],
"type": "Chemical"
} | tachycardia | {
"id": "696",
"normalized": [
{
"db_id": "D013610",
"db_name": "MESH"
}
],
"offsets": [
[
588,
599
]
],
"text": [
"tachycardia"
],
"type": "Disease"
} | [
{
"id": "693",
"normalized": [
{
"db_id": "D012964",
"db_name": "MESH"
}
],
"offsets": [
[
132,
138
]
],
"text": [
"sodium"
],
"type": "Chemical"
},
{
"id": "694",
"normalized": [
{
"db_id": "D009... | [
{
"id": "696",
"normalized": [
{
"db_id": "D013610",
"db_name": "MESH"
}
],
"offsets": [
[
588,
599
]
],
"text": [
"tachycardia"
],
"type": "Disease"
},
{
"id": "698",
"normalized": [
{
"db_id": "... | Inhibition of sympathoadrenal activity by atrial natriuretic factor in dogs. | In six conscious, trained dogs, maintained on a normal sodium intake of 2 to 4 mEq/kg/day, sympathetic activity was assessed as the release rate of norepinephrine and epinephrine during 15-minute i.v. infusions of human alpha-atrial natriuretic factor. Mean arterial pressure (as a percentage of control +/- SEM) during ... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Etoposide"/ induces disease /"pulmonary obstruction"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Death from chemotherapy in gestational trophoblastic disease.
- Abstract: Multiple cytotoxi... | Yes | Death from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | Etoposide | {
"id": "710",
"normalized": [
{
"db_id": "D005047",
"db_name": "MESH"
}
],
"offsets": [
[
399,
408
]
],
"text": [
"Etoposide"
],
"type": "Chemical"
} | pulmonary obstruction | {
"id": "718",
"normalized": [
{
"db_id": "D011655",
"db_name": "MESH"
}
],
"offsets": [
[
701,
722
]
],
"text": [
"pulmonary obstruction"
],
"type": "Disease"
} | [
{
"id": "710",
"normalized": [
{
"db_id": "D005047",
"db_name": "MESH"
}
],
"offsets": [
[
399,
408
]
],
"text": [
"Etoposide"
],
"type": "Chemical"
},
{
"id": "711",
"normalized": [
{
"db_id": "D... | [
{
"id": "707",
"normalized": [
{
"db_id": "D003643",
"db_name": "MESH"
}
],
"offsets": [
[
0,
5
]
],
"text": [
"Death"
],
"type": "Disease"
},
{
"id": "708",
"normalized": [
{
"db_id": "D031901",
... | Death from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Methotrexate"/ induces disease /"pulmonary obstruction"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Death from chemotherapy in gestational trophoblastic disease.
- Abstract: Multiple cytot... | Yes | Death from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | Methotrexate | {
"id": "711",
"normalized": [
{
"db_id": "D008727",
"db_name": "MESH"
}
],
"offsets": [
[
417,
429
]
],
"text": [
"Methotrexate"
],
"type": "Chemical"
} | pulmonary obstruction | {
"id": "718",
"normalized": [
{
"db_id": "D011655",
"db_name": "MESH"
}
],
"offsets": [
[
701,
722
]
],
"text": [
"pulmonary obstruction"
],
"type": "Disease"
} | [
{
"id": "710",
"normalized": [
{
"db_id": "D005047",
"db_name": "MESH"
}
],
"offsets": [
[
399,
408
]
],
"text": [
"Etoposide"
],
"type": "Chemical"
},
{
"id": "711",
"normalized": [
{
"db_id": "D... | [
{
"id": "707",
"normalized": [
{
"db_id": "D003643",
"db_name": "MESH"
}
],
"offsets": [
[
0,
5
]
],
"text": [
"Death"
],
"type": "Disease"
},
{
"id": "708",
"normalized": [
{
"db_id": "D031901",
... | Death from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Cyclophosphamide"/ induces disease /"pulmonary obstruction"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Death from chemotherapy in gestational trophoblastic disease.
- Abstract: Multiple c... | Yes | Death from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | Cyclophosphamide | {
"id": "712",
"normalized": [
{
"db_id": "D003520",
"db_name": "MESH"
}
],
"offsets": [
[
431,
447
]
],
"text": [
"Cyclophosphamide"
],
"type": "Chemical"
} | pulmonary obstruction | {
"id": "718",
"normalized": [
{
"db_id": "D011655",
"db_name": "MESH"
}
],
"offsets": [
[
701,
722
]
],
"text": [
"pulmonary obstruction"
],
"type": "Disease"
} | [
{
"id": "710",
"normalized": [
{
"db_id": "D005047",
"db_name": "MESH"
}
],
"offsets": [
[
399,
408
]
],
"text": [
"Etoposide"
],
"type": "Chemical"
},
{
"id": "711",
"normalized": [
{
"db_id": "D... | [
{
"id": "707",
"normalized": [
{
"db_id": "D003643",
"db_name": "MESH"
}
],
"offsets": [
[
0,
5
]
],
"text": [
"Death"
],
"type": "Disease"
},
{
"id": "708",
"normalized": [
{
"db_id": "D031901",
... | Death from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Methotrexate"/ induces disease /"Death"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Death"/ from chemotherapy in gestational trophoblastic disease.
- Abstract: Multiple cytotoxic drug ad... | No | /"Death"/ from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | Methotrexate | {
"id": "711",
"normalized": [
{
"db_id": "D008727",
"db_name": "MESH"
}
],
"offsets": [
[
417,
429
]
],
"text": [
"Methotrexate"
],
"type": "Chemical"
} | Death | {
"id": "707",
"normalized": [
{
"db_id": "D003643",
"db_name": "MESH"
}
],
"offsets": [
[
0,
5
]
],
"text": [
"Death"
],
"type": "Disease"
} | [
{
"id": "710",
"normalized": [
{
"db_id": "D005047",
"db_name": "MESH"
}
],
"offsets": [
[
399,
408
]
],
"text": [
"Etoposide"
],
"type": "Chemical"
},
{
"id": "711",
"normalized": [
{
"db_id": "D... | [
{
"id": "707",
"normalized": [
{
"db_id": "D003643",
"db_name": "MESH"
}
],
"offsets": [
[
0,
5
]
],
"text": [
"Death"
],
"type": "Disease"
},
{
"id": "708",
"normalized": [
{
"db_id": "D031901",
... | Death from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Cyclophosphamide"/ induces disease /"tumor"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Death from chemotherapy in gestational trophoblastic disease.
- Abstract: Multiple cytotoxic drug ad... | No | Death from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | Cyclophosphamide | {
"id": "712",
"normalized": [
{
"db_id": "D003520",
"db_name": "MESH"
}
],
"offsets": [
[
431,
447
]
],
"text": [
"Cyclophosphamide"
],
"type": "Chemical"
} | tumor | {
"id": "719",
"normalized": [
{
"db_id": "D009369",
"db_name": "MESH"
}
],
"offsets": [
[
854,
859
]
],
"text": [
"tumor"
],
"type": "Disease"
} | [
{
"id": "710",
"normalized": [
{
"db_id": "D005047",
"db_name": "MESH"
}
],
"offsets": [
[
399,
408
]
],
"text": [
"Etoposide"
],
"type": "Chemical"
},
{
"id": "711",
"normalized": [
{
"db_id": "D... | [
{
"id": "707",
"normalized": [
{
"db_id": "D003643",
"db_name": "MESH"
}
],
"offsets": [
[
0,
5
]
],
"text": [
"Death"
],
"type": "Disease"
},
{
"id": "708",
"normalized": [
{
"db_id": "D031901",
... | Death from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Cisplatin"/ induces disease /"pulmonary obstruction"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Death from chemotherapy in gestational trophoblastic disease.
- Abstract: Multiple cytotoxi... | No | Death from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | Cisplatin | {
"id": "714",
"normalized": [
{
"db_id": "D002945",
"db_name": "MESH"
}
],
"offsets": [
[
466,
475
]
],
"text": [
"Cisplatin"
],
"type": "Chemical"
} | pulmonary obstruction | {
"id": "718",
"normalized": [
{
"db_id": "D011655",
"db_name": "MESH"
}
],
"offsets": [
[
701,
722
]
],
"text": [
"pulmonary obstruction"
],
"type": "Disease"
} | [
{
"id": "710",
"normalized": [
{
"db_id": "D005047",
"db_name": "MESH"
}
],
"offsets": [
[
399,
408
]
],
"text": [
"Etoposide"
],
"type": "Chemical"
},
{
"id": "711",
"normalized": [
{
"db_id": "D... | [
{
"id": "707",
"normalized": [
{
"db_id": "D003643",
"db_name": "MESH"
}
],
"offsets": [
[
0,
5
]
],
"text": [
"Death"
],
"type": "Disease"
},
{
"id": "708",
"normalized": [
{
"db_id": "D031901",
... | Death from chemotherapy in gestational trophoblastic disease. | Multiple cytotoxic drug administration is the generally accepted treatment of patients with a high-risk stage of choriocarcinoma. Based on this principle a 27-year old woman, classified as being in the high-risk group (Goldstein and Berkowitz score: 11), was treated with multiple cytotoxic drugs. The multiple drug sche... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"methotrexate"/ induces disease /"Impotence"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Sexual dysfunction among patients with arthritis.
- Abstract: The relationship of arthritis and sexu... | Yes | Sexual dysfunction among patients with arthritis. | The relationship of arthritis and sexual dysfunction was investigated among 169 patients with rheumatoid arthritis, osteoarthritis and spondyloarthropathy, 130 of whom were pair-matched to controls. Assessments of marital happiness and depressed mood were also made using the CES-D and the Azrin Marital Happiness Scale ... | methotrexate | {
"id": "746",
"normalized": [
{
"db_id": "D008727",
"db_name": "MESH"
}
],
"offsets": [
[
642,
654
]
],
"text": [
"methotrexate"
],
"type": "Chemical"
} | Impotence | {
"id": "745",
"normalized": [
{
"db_id": "D007172",
"db_name": "MESH"
}
],
"offsets": [
[
515,
524
]
],
"text": [
"Impotence"
],
"type": "Disease"
} | [
{
"id": "746",
"normalized": [
{
"db_id": "D008727",
"db_name": "MESH"
}
],
"offsets": [
[
642,
654
]
],
"text": [
"methotrexate"
],
"type": "Chemical"
}
] | [
{
"id": "736",
"normalized": [
{
"db_id": "D012735",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Sexual dysfunction"
],
"type": "Disease"
},
{
"id": "737",
"normalized": [
{
"db_id... | Sexual dysfunction among patients with arthritis. | The relationship of arthritis and sexual dysfunction was investigated among 169 patients with rheumatoid arthritis, osteoarthritis and spondyloarthropathy, 130 of whom were pair-matched to controls. Assessments of marital happiness and depressed mood were also made using the CES-D and the Azrin Marital Happiness Scale ... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"methotrexate"/ induces disease /"Sexual dysfunction"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Sexual dysfunction"/ among patients with arthritis.
- Abstract: The relationship of arthr... | No | /"Sexual dysfunction"/ among patients with arthritis. | The relationship of arthritis and /"sexual dysfunction"/ was investigated among 169 patients with rheumatoid arthritis, osteoarthritis and spondyloarthropathy, 130 of whom were pair-matched to controls. Assessments of marital happiness and depressed mood were also made using the CES-D and the Azrin Marital Happiness Sc... | methotrexate | {
"id": "746",
"normalized": [
{
"db_id": "D008727",
"db_name": "MESH"
}
],
"offsets": [
[
642,
654
]
],
"text": [
"methotrexate"
],
"type": "Chemical"
} | Sexual dysfunction | {
"id": "736",
"normalized": [
{
"db_id": "D012735",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Sexual dysfunction"
],
"type": "Disease"
} | [
{
"id": "746",
"normalized": [
{
"db_id": "D008727",
"db_name": "MESH"
}
],
"offsets": [
[
642,
654
]
],
"text": [
"methotrexate"
],
"type": "Chemical"
}
] | [
{
"id": "736",
"normalized": [
{
"db_id": "D012735",
"db_name": "MESH"
}
],
"offsets": [
[
0,
18
]
],
"text": [
"Sexual dysfunction"
],
"type": "Disease"
},
{
"id": "737",
"normalized": [
{
"db_id... | Sexual dysfunction among patients with arthritis. | The relationship of arthritis and sexual dysfunction was investigated among 169 patients with rheumatoid arthritis, osteoarthritis and spondyloarthropathy, 130 of whom were pair-matched to controls. Assessments of marital happiness and depressed mood were also made using the CES-D and the Azrin Marital Happiness Scale ... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"phenacetin"/ induces disease /"renal papillary necrosis"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Does paracetamol cause urothelial cancer or /"renal papillary necrosis"/?
- Abstract: T... | Yes | Does paracetamol cause urothelial cancer or /"renal papillary necrosis"/? | The risk of developing /"renal papillary necrosis"/ or cancer of the renal pelvis, ureter or bladder associated with consumption of either /"phenacetin"/ or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of /"renal papillary necrosis"/ was increased nearly 20-fo... | phenacetin | {
"id": "764",
"normalized": [
{
"db_id": "D010615",
"db_name": "MESH"
}
],
"offsets": [
[
205,
215
]
],
"text": [
"phenacetin"
],
"type": "Chemical"
} | renal papillary necrosis | {
"id": "758",
"normalized": [
{
"db_id": "D007681",
"db_name": "MESH"
}
],
"offsets": [
[
44,
68
]
],
"text": [
"renal papillary necrosis"
],
"type": "Disease"
} | [
{
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
},
{
"id": "764",
"normalized": [
{
"db_id": "D0... | [
{
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
},
{
"id": "758",
"normalized": [
{
"db_id... | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by consum... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"phenacetin"/ induces disease /"cancer of the renal pelvis, ureter or bladder"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Does paracetamol cause urothelial cancer or renal papillary necros... | Yes | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or /"cancer of the renal pelvis, ureter or bladder"/ associated with consumption of either /"phenacetin"/ or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold b... | phenacetin | {
"id": "764",
"normalized": [
{
"db_id": "D010615",
"db_name": "MESH"
}
],
"offsets": [
[
205,
215
]
],
"text": [
"phenacetin"
],
"type": "Chemical"
} | cancer of the renal pelvis, ureter or bladder | {
"id": "760",
"normalized": [
{
"db_id": "D007680",
"db_name": "MESH"
},
{
"db_id": "D014516",
"db_name": "MESH"
},
{
"db_id": "D001749",
"db_name": "MESH"
}
],
"offsets": [
[
121,
166
]
],
"text": [
"cancer of the renal pe... | [
{
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
},
{
"id": "764",
"normalized": [
{
"db_id": "D0... | [
{
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
},
{
"id": "758",
"normalized": [
{
"db_id... | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by consum... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"phenacetin"/ induces disease /"cancer of the"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Does paracetamol cause urothelial cancer or renal papillary necrosis?
- Abstract: The risk of deve... | Yes | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or /"cancer of the"/ renal pelvis, ureter or /"cancer of the"/ associated with consumption of either /"phenacetin"/ or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly... | phenacetin | {
"id": "764",
"normalized": [
{
"db_id": "D010615",
"db_name": "MESH"
}
],
"offsets": [
[
205,
215
]
],
"text": [
"phenacetin"
],
"type": "Chemical"
} | cancer of the | {
"id": "763",
"normalized": [
{
"db_id": "D001749",
"db_name": "MESH"
}
],
"offsets": [
[
121,
134
],
[
159,
166
]
],
"text": [
"cancer of the",
"bladder"
],
"type": "Disease"
} | [
{
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
},
{
"id": "764",
"normalized": [
{
"db_id": "D0... | [
{
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
},
{
"id": "758",
"normalized": [
{
"db_id... | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by consum... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"phenacetin"/ induces disease /"cancer of the renal pelvis and bladder"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Does paracetamol cause urothelial cancer or renal papillary necrosis?
- A... | Yes | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either /"phenacetin"/ or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by co... | phenacetin | {
"id": "764",
"normalized": [
{
"db_id": "D010615",
"db_name": "MESH"
}
],
"offsets": [
[
205,
215
]
],
"text": [
"phenacetin"
],
"type": "Chemical"
} | cancer of the renal pelvis and bladder | {
"id": "768",
"normalized": [
{
"db_id": "D007680",
"db_name": "MESH"
},
{
"db_id": "D001749",
"db_name": "MESH"
}
],
"offsets": [
[
445,
483
]
],
"text": [
"cancer of the renal pelvis and bladder"
],
"type": "Disease"
} | [
{
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
},
{
"id": "764",
"normalized": [
{
"db_id": "D0... | [
{
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
},
{
"id": "758",
"normalized": [
{
"db_id... | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by consum... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"phenacetin"/ induces disease /"cancer of the renal pelvis"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Does paracetamol cause urothelial cancer or renal papillary necrosis?
- Abstract: The... | Yes | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or /"cancer of the renal pelvis"/, ureter or bladder associated with consumption of either /"phenacetin"/ or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold b... | phenacetin | {
"id": "764",
"normalized": [
{
"db_id": "D010615",
"db_name": "MESH"
}
],
"offsets": [
[
205,
215
]
],
"text": [
"phenacetin"
],
"type": "Chemical"
} | cancer of the renal pelvis | {
"id": "761",
"normalized": [
{
"db_id": "D007680",
"db_name": "MESH"
}
],
"offsets": [
[
121,
147
]
],
"text": [
"cancer of the renal pelvis"
],
"type": "Disease"
} | [
{
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
},
{
"id": "764",
"normalized": [
{
"db_id": "D0... | [
{
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
},
{
"id": "758",
"normalized": [
{
"db_id... | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by consum... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"phenacetin"/ induces disease /"urothelial cancer"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Does paracetamol cause /"urothelial cancer"/ or renal papillary necrosis?
- Abstract: The risk... | No | Does paracetamol cause /"urothelial cancer"/ or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either /"phenacetin"/ or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by co... | phenacetin | {
"id": "764",
"normalized": [
{
"db_id": "D010615",
"db_name": "MESH"
}
],
"offsets": [
[
205,
215
]
],
"text": [
"phenacetin"
],
"type": "Chemical"
} | urothelial cancer | {
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
} | [
{
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
},
{
"id": "764",
"normalized": [
{
"db_id": "D0... | [
{
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
},
{
"id": "758",
"normalized": [
{
"db_id... | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by consum... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"paracetamol"/ induces disease /"cancer of the"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Does /"paracetamol"/ cause urothelial cancer or renal papillary necrosis?
- Abstract: The risk of... | No | Does /"paracetamol"/ cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or /"cancer of the"/ renal pelvis, ureter or /"cancer of the"/ associated with consumption of either phenacetin or /"paracetamol"/ was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly... | paracetamol | {
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
} | cancer of the | {
"id": "763",
"normalized": [
{
"db_id": "D001749",
"db_name": "MESH"
}
],
"offsets": [
[
121,
134
],
[
159,
166
]
],
"text": [
"cancer of the",
"bladder"
],
"type": "Disease"
} | [
{
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
},
{
"id": "764",
"normalized": [
{
"db_id": "D0... | [
{
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
},
{
"id": "758",
"normalized": [
{
"db_id... | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by consum... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"phenacetin"/ induces disease /"cancers"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Does paracetamol cause urothelial cancer or renal papillary necrosis?
- Abstract: The risk of developing... | No | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either /"phenacetin"/ or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by co... | phenacetin | {
"id": "764",
"normalized": [
{
"db_id": "D010615",
"db_name": "MESH"
}
],
"offsets": [
[
205,
215
]
],
"text": [
"phenacetin"
],
"type": "Chemical"
} | cancers | {
"id": "774",
"normalized": [
{
"db_id": "D009369",
"db_name": "MESH"
}
],
"offsets": [
[
649,
656
]
],
"text": [
"cancers"
],
"type": "Disease"
} | [
{
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
},
{
"id": "764",
"normalized": [
{
"db_id": "D0... | [
{
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
},
{
"id": "758",
"normalized": [
{
"db_id... | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by consum... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"paracetamol"/ induces disease /"urothelial cancer"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Does /"paracetamol"/ cause /"urothelial cancer"/ or renal papillary necrosis?
- Abstract: The... | No | Does /"paracetamol"/ cause /"urothelial cancer"/ or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or /"paracetamol"/ was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by co... | paracetamol | {
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
} | urothelial cancer | {
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
} | [
{
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
},
{
"id": "764",
"normalized": [
{
"db_id": "D0... | [
{
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
},
{
"id": "758",
"normalized": [
{
"db_id... | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by consum... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"paracetamol"/ induces disease /"cancer of the renal pelvis and bladder"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Does /"paracetamol"/ cause urothelial cancer or renal papillary necrosis... | No | Does /"paracetamol"/ cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or /"paracetamol"/ was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by co... | paracetamol | {
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
} | cancer of the renal pelvis and bladder | {
"id": "768",
"normalized": [
{
"db_id": "D007680",
"db_name": "MESH"
},
{
"db_id": "D001749",
"db_name": "MESH"
}
],
"offsets": [
[
445,
483
]
],
"text": [
"cancer of the renal pelvis and bladder"
],
"type": "Disease"
} | [
{
"id": "756",
"normalized": [
{
"db_id": "D000082",
"db_name": "MESH"
}
],
"offsets": [
[
5,
16
]
],
"text": [
"paracetamol"
],
"type": "Chemical"
},
{
"id": "764",
"normalized": [
{
"db_id": "D0... | [
{
"id": "757",
"normalized": [
{
"db_id": "D014523",
"db_name": "MESH"
}
],
"offsets": [
[
23,
40
]
],
"text": [
"urothelial cancer"
],
"type": "Disease"
},
{
"id": "758",
"normalized": [
{
"db_id... | Does paracetamol cause urothelial cancer or renal papillary necrosis? | The risk of developing renal papillary necrosis or cancer of the renal pelvis, ureter or bladder associated with consumption of either phenacetin or paracetamol was calculated from data acquired by questionnaire from 381 cases and 808 controls. The risk of renal papillary necrosis was increased nearly 20-fold by consum... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Dapsone"/ induces disease /"hemolytic anemia"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Dapsone"/-associated Heinz body /"hemolytic anemia"/ in a Cambodian woman with hemoglobin E trai... | Yes | /"Dapsone"/-associated Heinz body /"hemolytic anemia"/ in a Cambodian woman with hemoglobin E trait. | A Cambodian woman with hemoglobin E trait (AE) and leprosy developed a Heinz body /"hemolytic anemia"/ while taking a dose of /"dapsone"/ (50 mg/day) not usually associated with clinical hemolysis. Her red blood cells (RBCs) had increased incubated Heinz body formation, decreased reduced glutathione (GSH), and decrease... | Dapsone | {
"id": "803",
"normalized": [
{
"db_id": "D003622",
"db_name": "MESH"
}
],
"offsets": [
[
0,
7
]
],
"text": [
"Dapsone"
],
"type": "Chemical"
} | hemolytic anemia | {
"id": "804",
"normalized": [
{
"db_id": "D000743",
"db_name": "MESH"
}
],
"offsets": [
[
30,
46
]
],
"text": [
"hemolytic anemia"
],
"type": "Disease"
} | [
{
"id": "803",
"normalized": [
{
"db_id": "D003622",
"db_name": "MESH"
}
],
"offsets": [
[
0,
7
]
],
"text": [
"Dapsone"
],
"type": "Chemical"
},
{
"id": "807",
"normalized": [
{
"db_id": "D003622... | [
{
"id": "804",
"normalized": [
{
"db_id": "D000743",
"db_name": "MESH"
}
],
"offsets": [
[
30,
46
]
],
"text": [
"hemolytic anemia"
],
"type": "Disease"
},
{
"id": "805",
"normalized": [
{
"db_id"... | Dapsone-associated Heinz body hemolytic anemia in a Cambodian woman with hemoglobin E trait. | A Cambodian woman with hemoglobin E trait (AE) and leprosy developed a Heinz body hemolytic anemia while taking a dose of dapsone (50 mg/day) not usually associated with clinical hemolysis. Her red blood cells (RBCs) had increased incubated Heinz body formation, decreased reduced glutathione (GSH), and decreased GSH st... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Dapsone"/ induces disease /"leprosy"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Dapsone"/-associated Heinz body hemolytic anemia in a Cambodian woman with hemoglobin E trait.
- Abstract... | No | /"Dapsone"/-associated Heinz body hemolytic anemia in a Cambodian woman with hemoglobin E trait. | A Cambodian woman with hemoglobin E trait (AE) and /"leprosy"/ developed a Heinz body hemolytic anemia while taking a dose of /"dapsone"/ (50 mg/day) not usually associated with clinical hemolysis. Her red blood cells (RBCs) had increased incubated Heinz body formation, decreased reduced glutathione (GSH), and decrease... | Dapsone | {
"id": "803",
"normalized": [
{
"db_id": "D003622",
"db_name": "MESH"
}
],
"offsets": [
[
0,
7
]
],
"text": [
"Dapsone"
],
"type": "Chemical"
} | leprosy | {
"id": "805",
"normalized": [
{
"db_id": "D007918",
"db_name": "MESH"
}
],
"offsets": [
[
144,
151
]
],
"text": [
"leprosy"
],
"type": "Disease"
} | [
{
"id": "803",
"normalized": [
{
"db_id": "D003622",
"db_name": "MESH"
}
],
"offsets": [
[
0,
7
]
],
"text": [
"Dapsone"
],
"type": "Chemical"
},
{
"id": "807",
"normalized": [
{
"db_id": "D003622... | [
{
"id": "804",
"normalized": [
{
"db_id": "D000743",
"db_name": "MESH"
}
],
"offsets": [
[
30,
46
]
],
"text": [
"hemolytic anemia"
],
"type": "Disease"
},
{
"id": "805",
"normalized": [
{
"db_id"... | Dapsone-associated Heinz body hemolytic anemia in a Cambodian woman with hemoglobin E trait. | A Cambodian woman with hemoglobin E trait (AE) and leprosy developed a Heinz body hemolytic anemia while taking a dose of dapsone (50 mg/day) not usually associated with clinical hemolysis. Her red blood cells (RBCs) had increased incubated Heinz body formation, decreased reduced glutathione (GSH), and decreased GSH st... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"diltiazem"/ induces disease /"hypotension"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of met... | Yes | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, /"diltiazem"/, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe /"hypotension"/, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days be... | diltiazem | {
"id": "845",
"normalized": [
{
"db_id": "D004110",
"db_name": "MESH"
}
],
"offsets": [
[
123,
132
]
],
"text": [
"diltiazem"
],
"type": "Chemical"
} | hypotension | {
"id": "850",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
270,
281
]
],
"text": [
"hypotension"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"diltiazem"/ induces disease /"impairment of ventricular function"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as a ... | Yes | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, /"diltiazem"/, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and /"impairment of ventricular function"/. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days be... | diltiazem | {
"id": "845",
"normalized": [
{
"db_id": "D004110",
"db_name": "MESH"
}
],
"offsets": [
[
123,
132
]
],
"text": [
"diltiazem"
],
"type": "Chemical"
} | impairment of ventricular function | {
"id": "851",
"normalized": [
{
"db_id": "D018754",
"db_name": "MESH"
}
],
"offsets": [
[
287,
321
]
],
"text": [
"impairment of ventricular function"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"metoprolol"/ induces disease /"impairment of ventricular function"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as a... | Yes | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of /"metoprolol"/, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and /"impairment of ventricular function"/. One week prior to admission a therapy with standard doses of /"metoprolol"/ (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two day... | metoprolol | {
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
} | impairment of ventricular function | {
"id": "851",
"normalized": [
{
"db_id": "D018754",
"db_name": "MESH"
}
],
"offsets": [
[
287,
321
]
],
"text": [
"impairment of ventricular function"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"metoprolol"/ induces disease /"hypotension"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of /"... | Yes | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of /"metoprolol"/, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe /"hypotension"/, and impairment of ventricular function. One week prior to admission a therapy with standard doses of /"metoprolol"/ (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two day... | metoprolol | {
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
} | hypotension | {
"id": "850",
"normalized": [
{
"db_id": "D007022",
"db_name": "MESH"
}
],
"offsets": [
[
270,
281
]
],
"text": [
"hypotension"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"diltiazem"/ induces disease /"AV block"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metopr... | Yes | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, /"diltiazem"/, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. /"AV block"/, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days be... | diltiazem | {
"id": "845",
"normalized": [
{
"db_id": "D004110",
"db_name": "MESH"
}
],
"offsets": [
[
123,
132
]
],
"text": [
"diltiazem"
],
"type": "Chemical"
} | AV block | {
"id": "849",
"normalized": [
{
"db_id": "D054537",
"db_name": "MESH"
}
],
"offsets": [
[
253,
261
]
],
"text": [
"AV block"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"metoprolol"/ induces disease /"AV block"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of /"met... | Yes | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of /"metoprolol"/, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. /"AV block"/, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of /"metoprolol"/ (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two day... | metoprolol | {
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
} | AV block | {
"id": "849",
"normalized": [
{
"db_id": "D054537",
"db_name": "MESH"
}
],
"offsets": [
[
253,
261
]
],
"text": [
"AV block"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"sparteine"/ induces disease /"shock"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolo... | No | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and /"sparteine"/. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in /"shock"/ with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days be... | sparteine | {
"id": "846",
"normalized": [
{
"db_id": "D013034",
"db_name": "MESH"
}
],
"offsets": [
[
138,
147
]
],
"text": [
"sparteine"
],
"type": "Chemical"
} | shock | {
"id": "848",
"normalized": [
{
"db_id": "D012769",
"db_name": "MESH"
}
],
"offsets": [
[
237,
242
]
],
"text": [
"shock"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"debrisoquine"/ induces disease /"impairment of ventricular function"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as... | No | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and /"impairment of ventricular function"/. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days be... | debrisoquine | {
"id": "860",
"normalized": [
{
"db_id": "D003647",
"db_name": "MESH"
}
],
"offsets": [
[
938,
950
]
],
"text": [
"debrisoquine"
],
"type": "Chemical"
} | impairment of ventricular function | {
"id": "851",
"normalized": [
{
"db_id": "D018754",
"db_name": "MESH"
}
],
"offsets": [
[
287,
321
]
],
"text": [
"impairment of ventricular function"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"propafenone"/ induces disease /"adverse drug reactions"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as a poor metab... | No | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, /"propafenone"/, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | propafenone | {
"id": "844",
"normalized": [
{
"db_id": "D011405",
"db_name": "MESH"
}
],
"offsets": [
[
110,
121
]
],
"text": [
"propafenone"
],
"type": "Chemical"
} | adverse drug reactions | {
"id": "864",
"normalized": [
{
"db_id": "D064420",
"db_name": "MESH"
}
],
"offsets": [
[
1328,
1350
]
],
"text": [
"adverse drug reactions"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"diltiazem"/ induces disease /"adverse drug reactions"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as a poor metabol... | No | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, /"diltiazem"/, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | diltiazem | {
"id": "845",
"normalized": [
{
"db_id": "D004110",
"db_name": "MESH"
}
],
"offsets": [
[
123,
132
]
],
"text": [
"diltiazem"
],
"type": "Chemical"
} | adverse drug reactions | {
"id": "864",
"normalized": [
{
"db_id": "D064420",
"db_name": "MESH"
}
],
"offsets": [
[
1328,
1350
]
],
"text": [
"adverse drug reactions"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"debrisoquine"/ induces disease /"shock"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metopr... | No | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in /"shock"/ with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days be... | debrisoquine | {
"id": "860",
"normalized": [
{
"db_id": "D003647",
"db_name": "MESH"
}
],
"offsets": [
[
938,
950
]
],
"text": [
"debrisoquine"
],
"type": "Chemical"
} | shock | {
"id": "848",
"normalized": [
{
"db_id": "D012769",
"db_name": "MESH"
}
],
"offsets": [
[
237,
242
]
],
"text": [
"shock"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"sparteine"/ induces disease /"impairment of ventricular function"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Severe complications of antianginal drug therapy in a patient identified as a ... | No | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and /"sparteine"/. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and /"impairment of ventricular function"/. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days be... | sparteine | {
"id": "846",
"normalized": [
{
"db_id": "D013034",
"db_name": "MESH"
}
],
"offsets": [
[
138,
147
]
],
"text": [
"sparteine"
],
"type": "Chemical"
} | impairment of ventricular function | {
"id": "851",
"normalized": [
{
"db_id": "D018754",
"db_name": "MESH"
}
],
"offsets": [
[
287,
321
]
],
"text": [
"impairment of ventricular function"
],
"type": "Disease"
} | [
{
"id": "843",
"normalized": [
{
"db_id": "D008790",
"db_name": "MESH"
}
],
"offsets": [
[
98,
108
]
],
"text": [
"metoprolol"
],
"type": "Chemical"
},
{
"id": "844",
"normalized": [
{
"db_id": "D... | [
{
"id": "847",
"normalized": [
{
"db_id": "D003324",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"coronary artery disease"
],
"type": "Disease"
},
{
"id": "848",
"normalized": [
{
... | Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine. | A 47-year-old patient suffering from coronary artery disease was admitted to the CCU in shock with III. AV block, severe hypotension, and impairment of ventricular function. One week prior to admission a therapy with standard doses of metoprolol (100 mg t.i.d. and then 100 mg b.i.d.) had been initiated. Two days before... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Triazolam"/ induces disease /"mania"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Triazolam"/-induced brief episodes of secondary /"mania"/ in a depressed patient.
- Abstract: Large doses... | Yes | /"Triazolam"/-induced brief episodes of secondary /"mania"/ in a depressed patient. | Large doses of /"triazolam"/ repeatedly induced brief episodes of /"mania"/ in a depressed elderly woman. Features of organic mental disorder (delirium) were not present. /"Manic"/ excitement was coincident with the duration of action of /"triazolam"/. The possible contribution of the /"triazolo"/ group to changes in a... | Triazolam | {
"id": "892",
"normalized": [
{
"db_id": "D014229",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Triazolam"
],
"type": "Chemical"
} | mania | {
"id": "893",
"normalized": [
{
"db_id": "D001714",
"db_name": "MESH"
}
],
"offsets": [
[
46,
51
]
],
"text": [
"mania"
],
"type": "Disease"
} | [
{
"id": "892",
"normalized": [
{
"db_id": "D014229",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Triazolam"
],
"type": "Chemical"
},
{
"id": "895",
"normalized": [
{
"db_id": "D0142... | [
{
"id": "893",
"normalized": [
{
"db_id": "D001714",
"db_name": "MESH"
}
],
"offsets": [
[
46,
51
]
],
"text": [
"mania"
],
"type": "Disease"
},
{
"id": "894",
"normalized": [
{
"db_id": "D003866"... | Triazolam-induced brief episodes of secondary mania in a depressed patient. | Large doses of triazolam repeatedly induced brief episodes of mania in a depressed elderly woman. Features of organic mental disorder (delirium) were not present. Manic excitement was coincident with the duration of action of triazolam. The possible contribution of the triazolo group to changes in affective status is d... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"Triazolam"/ induces disease /"organic mental disorder"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Triazolam"/-induced brief episodes of secondary mania in a depressed patient.
- Abstrac... | No | /"Triazolam"/-induced brief episodes of secondary mania in a depressed patient. | Large doses of /"triazolam"/ repeatedly induced brief episodes of mania in a depressed elderly woman. Features of /"organic mental disorder"/ (delirium) were not present. Manic excitement was coincident with the duration of action of /"triazolam"/. The possible contribution of the /"triazolo"/ group to changes in affec... | Triazolam | {
"id": "892",
"normalized": [
{
"db_id": "D014229",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Triazolam"
],
"type": "Chemical"
} | organic mental disorder | {
"id": "898",
"normalized": [
{
"db_id": "D019965",
"db_name": "MESH"
}
],
"offsets": [
[
186,
209
]
],
"text": [
"organic mental disorder"
],
"type": "Disease"
} | [
{
"id": "892",
"normalized": [
{
"db_id": "D014229",
"db_name": "MESH"
}
],
"offsets": [
[
0,
9
]
],
"text": [
"Triazolam"
],
"type": "Chemical"
},
{
"id": "895",
"normalized": [
{
"db_id": "D0142... | [
{
"id": "893",
"normalized": [
{
"db_id": "D001714",
"db_name": "MESH"
}
],
"offsets": [
[
46,
51
]
],
"text": [
"mania"
],
"type": "Disease"
},
{
"id": "894",
"normalized": [
{
"db_id": "D003866"... | Triazolam-induced brief episodes of secondary mania in a depressed patient. | Large doses of triazolam repeatedly induced brief episodes of mania in a depressed elderly woman. Features of organic mental disorder (delirium) were not present. Manic excitement was coincident with the duration of action of triazolam. The possible contribution of the triazolo group to changes in affective status is d... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"haloperidol"/ induces disease /"muscular rigidity"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: On the mechanisms of the development of tolerance to the /"muscular rigidity"/ produced by mo... | Yes | On the mechanisms of the development of tolerance to the /"muscular rigidity"/ produced by morphine in rats. | The development of tolerance to the /"muscular rigidity"/ produced by morphine was studied in rats. Saline-pretreated controls given a test dose of morphine (20 mg/kg i.p.) showed a pronounced /"rigidity"/ recorded as tonic activity in the electromyogram. Rats treated for 11 days with morphine and withdrawn for 36-40 h... | haloperidol | {
"id": "932",
"normalized": [
{
"db_id": "D006220",
"db_name": "MESH"
}
],
"offsets": [
[
976,
987
]
],
"text": [
"haloperidol"
],
"type": "Chemical"
} | muscular rigidity | {
"id": "918",
"normalized": [
{
"db_id": "D009127",
"db_name": "MESH"
}
],
"offsets": [
[
57,
74
]
],
"text": [
"muscular rigidity"
],
"type": "Disease"
} | [
{
"id": "919",
"normalized": [
{
"db_id": "D009020",
"db_name": "MESH"
}
],
"offsets": [
[
87,
95
]
],
"text": [
"morphine"
],
"type": "Chemical"
},
{
"id": "921",
"normalized": [
{
"db_id": "D009... | [
{
"id": "918",
"normalized": [
{
"db_id": "D009127",
"db_name": "MESH"
}
],
"offsets": [
[
57,
74
]
],
"text": [
"muscular rigidity"
],
"type": "Disease"
},
{
"id": "920",
"normalized": [
{
"db_id... | On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rats. | The development of tolerance to the muscular rigidity produced by morphine was studied in rats. Saline-pretreated controls given a test dose of morphine (20 mg/kg i.p.) showed a pronounced rigidity recorded as tonic activity in the electromyogram. Rats treated for 11 days with morphine and withdrawn for 36-40 h showed ... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"morphine"/ induces disease /"muscular rigidity"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: On the mechanisms of the development of tolerance to the /"muscular rigidity"/ produced by /"mor... | Yes | On the mechanisms of the development of tolerance to the /"muscular rigidity"/ produced by /"morphine"/ in rats. | The development of tolerance to the /"muscular rigidity"/ produced by /"morphine"/ was studied in rats. Saline-pretreated controls given a test dose of /"morphine"/ (20 mg/kg i.p.) showed a pronounced /"rigidity"/ recorded as tonic activity in the electromyogram. Rats treated for 11 days with /"morphine"/ and withdrawn... | morphine | {
"id": "919",
"normalized": [
{
"db_id": "D009020",
"db_name": "MESH"
}
],
"offsets": [
[
87,
95
]
],
"text": [
"morphine"
],
"type": "Chemical"
} | muscular rigidity | {
"id": "918",
"normalized": [
{
"db_id": "D009127",
"db_name": "MESH"
}
],
"offsets": [
[
57,
74
]
],
"text": [
"muscular rigidity"
],
"type": "Disease"
} | [
{
"id": "919",
"normalized": [
{
"db_id": "D009020",
"db_name": "MESH"
}
],
"offsets": [
[
87,
95
]
],
"text": [
"morphine"
],
"type": "Chemical"
},
{
"id": "921",
"normalized": [
{
"db_id": "D009... | [
{
"id": "918",
"normalized": [
{
"db_id": "D009127",
"db_name": "MESH"
}
],
"offsets": [
[
57,
74
]
],
"text": [
"muscular rigidity"
],
"type": "Disease"
},
{
"id": "920",
"normalized": [
{
"db_id... | On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rats. | The development of tolerance to the muscular rigidity produced by morphine was studied in rats. Saline-pretreated controls given a test dose of morphine (20 mg/kg i.p.) showed a pronounced rigidity recorded as tonic activity in the electromyogram. Rats treated for 11 days with morphine and withdrawn for 36-40 h showed ... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"morphine"/ induces disease /"hyperkinetic"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: On the mechanisms of the development of tolerance to the muscular rigidity produced by /"morphine"/ i... | Yes | On the mechanisms of the development of tolerance to the muscular rigidity produced by /"morphine"/ in rats. | The development of tolerance to the muscular rigidity produced by /"morphine"/ was studied in rats. Saline-pretreated controls given a test dose of /"morphine"/ (20 mg/kg i.p.) showed a pronounced rigidity recorded as tonic activity in the electromyogram. Rats treated for 11 days with /"morphine"/ and withdrawn for 36-... | morphine | {
"id": "919",
"normalized": [
{
"db_id": "D009020",
"db_name": "MESH"
}
],
"offsets": [
[
87,
95
]
],
"text": [
"morphine"
],
"type": "Chemical"
} | hyperkinetic | {
"id": "930",
"normalized": [
{
"db_id": "D006948",
"db_name": "MESH"
}
],
"offsets": [
[
772,
784
]
],
"text": [
"hyperkinetic"
],
"type": "Disease"
} | [
{
"id": "919",
"normalized": [
{
"db_id": "D009020",
"db_name": "MESH"
}
],
"offsets": [
[
87,
95
]
],
"text": [
"morphine"
],
"type": "Chemical"
},
{
"id": "921",
"normalized": [
{
"db_id": "D009... | [
{
"id": "918",
"normalized": [
{
"db_id": "D009127",
"db_name": "MESH"
}
],
"offsets": [
[
57,
74
]
],
"text": [
"muscular rigidity"
],
"type": "Disease"
},
{
"id": "920",
"normalized": [
{
"db_id... | On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rats. | The development of tolerance to the muscular rigidity produced by morphine was studied in rats. Saline-pretreated controls given a test dose of morphine (20 mg/kg i.p.) showed a pronounced rigidity recorded as tonic activity in the electromyogram. Rats treated for 11 days with morphine and withdrawn for 36-40 h showed ... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"morphine"/ induces disease /"akinetic"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: On the mechanisms of the development of tolerance to the muscular rigidity produced by /"morphine"/ in ra... | Yes | On the mechanisms of the development of tolerance to the muscular rigidity produced by /"morphine"/ in rats. | The development of tolerance to the muscular rigidity produced by /"morphine"/ was studied in rats. Saline-pretreated controls given a test dose of /"morphine"/ (20 mg/kg i.p.) showed a pronounced rigidity recorded as tonic activity in the electromyogram. Rats treated for 11 days with /"morphine"/ and withdrawn for 36-... | morphine | {
"id": "919",
"normalized": [
{
"db_id": "D009020",
"db_name": "MESH"
}
],
"offsets": [
[
87,
95
]
],
"text": [
"morphine"
],
"type": "Chemical"
} | akinetic | {
"id": "927",
"normalized": [
{
"db_id": "D018476",
"db_name": "MESH"
}
],
"offsets": [
[
608,
616
]
],
"text": [
"akinetic"
],
"type": "Disease"
} | [
{
"id": "919",
"normalized": [
{
"db_id": "D009020",
"db_name": "MESH"
}
],
"offsets": [
[
87,
95
]
],
"text": [
"morphine"
],
"type": "Chemical"
},
{
"id": "921",
"normalized": [
{
"db_id": "D009... | [
{
"id": "918",
"normalized": [
{
"db_id": "D009127",
"db_name": "MESH"
}
],
"offsets": [
[
57,
74
]
],
"text": [
"muscular rigidity"
],
"type": "Disease"
},
{
"id": "920",
"normalized": [
{
"db_id... | On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rats. | The development of tolerance to the muscular rigidity produced by morphine was studied in rats. Saline-pretreated controls given a test dose of morphine (20 mg/kg i.p.) showed a pronounced rigidity recorded as tonic activity in the electromyogram. Rats treated for 11 days with morphine and withdrawn for 36-40 h showed ... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"haloperidol"/ induces disease /"hyperkinetic"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in... | No | On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rats. | The development of tolerance to the muscular rigidity produced by morphine was studied in rats. Saline-pretreated controls given a test dose of morphine (20 mg/kg i.p.) showed a pronounced rigidity recorded as tonic activity in the electromyogram. Rats treated for 11 days with morphine and withdrawn for 36-40 h showed ... | haloperidol | {
"id": "932",
"normalized": [
{
"db_id": "D006220",
"db_name": "MESH"
}
],
"offsets": [
[
976,
987
]
],
"text": [
"haloperidol"
],
"type": "Chemical"
} | hyperkinetic | {
"id": "930",
"normalized": [
{
"db_id": "D006948",
"db_name": "MESH"
}
],
"offsets": [
[
772,
784
]
],
"text": [
"hyperkinetic"
],
"type": "Disease"
} | [
{
"id": "919",
"normalized": [
{
"db_id": "D009020",
"db_name": "MESH"
}
],
"offsets": [
[
87,
95
]
],
"text": [
"morphine"
],
"type": "Chemical"
},
{
"id": "921",
"normalized": [
{
"db_id": "D009... | [
{
"id": "918",
"normalized": [
{
"db_id": "D009127",
"db_name": "MESH"
}
],
"offsets": [
[
57,
74
]
],
"text": [
"muscular rigidity"
],
"type": "Disease"
},
{
"id": "920",
"normalized": [
{
"db_id... | On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rats. | The development of tolerance to the muscular rigidity produced by morphine was studied in rats. Saline-pretreated controls given a test dose of morphine (20 mg/kg i.p.) showed a pronounced rigidity recorded as tonic activity in the electromyogram. Rats treated for 11 days with morphine and withdrawn for 36-40 h showed ... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"haloperidol"/ induces disease /"akinetic"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rat... | No | On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rats. | The development of tolerance to the muscular rigidity produced by morphine was studied in rats. Saline-pretreated controls given a test dose of morphine (20 mg/kg i.p.) showed a pronounced rigidity recorded as tonic activity in the electromyogram. Rats treated for 11 days with morphine and withdrawn for 36-40 h showed ... | haloperidol | {
"id": "932",
"normalized": [
{
"db_id": "D006220",
"db_name": "MESH"
}
],
"offsets": [
[
976,
987
]
],
"text": [
"haloperidol"
],
"type": "Chemical"
} | akinetic | {
"id": "927",
"normalized": [
{
"db_id": "D018476",
"db_name": "MESH"
}
],
"offsets": [
[
608,
616
]
],
"text": [
"akinetic"
],
"type": "Disease"
} | [
{
"id": "919",
"normalized": [
{
"db_id": "D009020",
"db_name": "MESH"
}
],
"offsets": [
[
87,
95
]
],
"text": [
"morphine"
],
"type": "Chemical"
},
{
"id": "921",
"normalized": [
{
"db_id": "D009... | [
{
"id": "918",
"normalized": [
{
"db_id": "D009127",
"db_name": "MESH"
}
],
"offsets": [
[
57,
74
]
],
"text": [
"muscular rigidity"
],
"type": "Disease"
},
{
"id": "920",
"normalized": [
{
"db_id... | On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rats. | The development of tolerance to the muscular rigidity produced by morphine was studied in rats. Saline-pretreated controls given a test dose of morphine (20 mg/kg i.p.) showed a pronounced rigidity recorded as tonic activity in the electromyogram. Rats treated for 11 days with morphine and withdrawn for 36-40 h showed ... | false |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"pentazocine"/ induces disease /"fibrous myopathy"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Compression neuropathy of the radial nerve due to /"pentazocine"/-induced /"fibrous myopathy"/... | Yes | Compression neuropathy of the radial nerve due to /"pentazocine"/-induced /"fibrous myopathy"/. | /"Fibrous myopathy"/ is a common, well-known side effect of repeated /"pentazocine"/ injection. However, compression neuropathy due to fibrotic muscle affected by /"pentazocine"/-induced myopathy has not previously been reported. In a 37-year-old woman with documented /"pentazocine"/-induced /"fibrous myopathy"/ of tri... | pentazocine | {
"id": "1043",
"normalized": [
{
"db_id": "D010423",
"db_name": "MESH"
}
],
"offsets": [
[
50,
61
]
],
"text": [
"pentazocine"
],
"type": "Chemical"
} | fibrous myopathy | {
"id": "1044",
"normalized": [
{
"db_id": "D005355",
"db_name": "MESH"
},
{
"db_id": "D009135",
"db_name": "MESH"
}
],
"offsets": [
[
70,
86
]
],
"text": [
"fibrous myopathy"
],
"type": "Disease"
} | [
{
"id": "1043",
"normalized": [
{
"db_id": "D010423",
"db_name": "MESH"
}
],
"offsets": [
[
50,
61
]
],
"text": [
"pentazocine"
],
"type": "Chemical"
},
{
"id": "1046",
"normalized": [
{
"db_id": ... | [
{
"id": "1040",
"normalized": [
{
"db_id": "D009408",
"db_name": "MESH"
},
{
"db_id": "D020425",
"db_name": "MESH"
}
],
"offsets": [
[
0,
42
]
],
"text": [
"Compression neuropathy of the radial nerve"
... | Compression neuropathy of the radial nerve due to pentazocine-induced fibrous myopathy. | Fibrous myopathy is a common, well-known side effect of repeated pentazocine injection. However, compression neuropathy due to fibrotic muscle affected by pentazocine-induced myopathy has not previously been reported. In a 37-year-old woman with documented pentazocine-induced fibrous myopathy of triceps and deltoid mus... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"pentazocine"/ induces disease /"myopathy"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Compression neuropathy of the radial nerve due to /"pentazocine"/-induced fibrous myopathy.
- Abstract... | Yes | Compression neuropathy of the radial nerve due to /"pentazocine"/-induced fibrous myopathy. | Fibrous myopathy is a common, well-known side effect of repeated /"pentazocine"/ injection. However, compression neuropathy due to fibrotic muscle affected by /"pentazocine"/-induced /"myopathy"/ has not previously been reported. In a 37-year-old woman with documented /"pentazocine"/-induced fibrous myopathy of triceps... | pentazocine | {
"id": "1043",
"normalized": [
{
"db_id": "D010423",
"db_name": "MESH"
}
],
"offsets": [
[
50,
61
]
],
"text": [
"pentazocine"
],
"type": "Chemical"
} | myopathy | {
"id": "1049",
"normalized": [
{
"db_id": "D009135",
"db_name": "MESH"
}
],
"offsets": [
[
263,
271
]
],
"text": [
"myopathy"
],
"type": "Disease"
} | [
{
"id": "1043",
"normalized": [
{
"db_id": "D010423",
"db_name": "MESH"
}
],
"offsets": [
[
50,
61
]
],
"text": [
"pentazocine"
],
"type": "Chemical"
},
{
"id": "1046",
"normalized": [
{
"db_id": ... | [
{
"id": "1040",
"normalized": [
{
"db_id": "D009408",
"db_name": "MESH"
},
{
"db_id": "D020425",
"db_name": "MESH"
}
],
"offsets": [
[
0,
42
]
],
"text": [
"Compression neuropathy of the radial nerve"
... | Compression neuropathy of the radial nerve due to pentazocine-induced fibrous myopathy. | Fibrous myopathy is a common, well-known side effect of repeated pentazocine injection. However, compression neuropathy due to fibrotic muscle affected by pentazocine-induced myopathy has not previously been reported. In a 37-year-old woman with documented pentazocine-induced fibrous myopathy of triceps and deltoid mus... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"pentazocine"/ induces disease /"Compression neuropathy of the radial nerve"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: /"Compression neuropathy of the radial nerve"/ due to /"pentazocine"... | Yes | /"Compression neuropathy of the radial nerve"/ due to /"pentazocine"/-induced fibrous myopathy. | Fibrous myopathy is a common, well-known side effect of repeated /"pentazocine"/ injection. However, compression neuropathy due to fibrotic muscle affected by /"pentazocine"/-induced myopathy has not previously been reported. In a 37-year-old woman with documented /"pentazocine"/-induced fibrous myopathy of triceps and... | pentazocine | {
"id": "1043",
"normalized": [
{
"db_id": "D010423",
"db_name": "MESH"
}
],
"offsets": [
[
50,
61
]
],
"text": [
"pentazocine"
],
"type": "Chemical"
} | Compression neuropathy of the radial nerve | {
"id": "1040",
"normalized": [
{
"db_id": "D009408",
"db_name": "MESH"
},
{
"db_id": "D020425",
"db_name": "MESH"
}
],
"offsets": [
[
0,
42
]
],
"text": [
"Compression neuropathy of the radial nerve"
],
"type": "Disease"
} | [
{
"id": "1043",
"normalized": [
{
"db_id": "D010423",
"db_name": "MESH"
}
],
"offsets": [
[
50,
61
]
],
"text": [
"pentazocine"
],
"type": "Chemical"
},
{
"id": "1046",
"normalized": [
{
"db_id": ... | [
{
"id": "1040",
"normalized": [
{
"db_id": "D009408",
"db_name": "MESH"
},
{
"db_id": "D020425",
"db_name": "MESH"
}
],
"offsets": [
[
0,
42
]
],
"text": [
"Compression neuropathy of the radial nerve"
... | Compression neuropathy of the radial nerve due to pentazocine-induced fibrous myopathy. | Fibrous myopathy is a common, well-known side effect of repeated pentazocine injection. However, compression neuropathy due to fibrotic muscle affected by pentazocine-induced myopathy has not previously been reported. In a 37-year-old woman with documented pentazocine-induced fibrous myopathy of triceps and deltoid mus... | true |
<s> [INST] <<SYS>>
Your task is to analyse the following medical article to determine whether chemical /"pentazocine"/ induces disease /"neuropathy of the radial nerve"/. You only need to answer Yes or No, nothing else.
<</SYS>>
- Title: Compression /"neuropathy of the radial nerve"/ due to /"pentazocine"/-induced fi... | Yes | Compression /"neuropathy of the radial nerve"/ due to /"pentazocine"/-induced fibrous myopathy. | Fibrous myopathy is a common, well-known side effect of repeated /"pentazocine"/ injection. However, compression neuropathy due to fibrotic muscle affected by /"pentazocine"/-induced myopathy has not previously been reported. In a 37-year-old woman with documented /"pentazocine"/-induced fibrous myopathy of triceps and... | pentazocine | {
"id": "1043",
"normalized": [
{
"db_id": "D010423",
"db_name": "MESH"
}
],
"offsets": [
[
50,
61
]
],
"text": [
"pentazocine"
],
"type": "Chemical"
} | neuropathy of the radial nerve | {
"id": "1042",
"normalized": [
{
"db_id": "D020425",
"db_name": "MESH"
}
],
"offsets": [
[
12,
42
]
],
"text": [
"neuropathy of the radial nerve"
],
"type": "Disease"
} | [
{
"id": "1043",
"normalized": [
{
"db_id": "D010423",
"db_name": "MESH"
}
],
"offsets": [
[
50,
61
]
],
"text": [
"pentazocine"
],
"type": "Chemical"
},
{
"id": "1046",
"normalized": [
{
"db_id": ... | [
{
"id": "1040",
"normalized": [
{
"db_id": "D009408",
"db_name": "MESH"
},
{
"db_id": "D020425",
"db_name": "MESH"
}
],
"offsets": [
[
0,
42
]
],
"text": [
"Compression neuropathy of the radial nerve"
... | Compression neuropathy of the radial nerve due to pentazocine-induced fibrous myopathy. | Fibrous myopathy is a common, well-known side effect of repeated pentazocine injection. However, compression neuropathy due to fibrotic muscle affected by pentazocine-induced myopathy has not previously been reported. In a 37-year-old woman with documented pentazocine-induced fibrous myopathy of triceps and deltoid mus... | true |
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