normalized_image_embeddings/README.md

# Normalized Image Embeddings and Biomarker Layer

This folder contains normalized imaging features and biomarker intensity summaries for Z-Screen compound-level morphology analyses.

## Files

-   `normalized_image_embeddings.parquet`
-   `biomarker_intensity_layer.parquet`

## Contents

`normalized_image_embeddings.parquet` contains public compound identifiers and normalized morphology features, including principal-component-style image features. In the current release audit, it contains 21,795 rows and 39 columns.

`biomarker_intensity_layer.parquet` contains public compound identifiers and intensity measurements for protein/cellular-state markers. In the current release audit, it contains 18,942 rows and 11 columns, including BRD4, p21/CDKN1A, DAPI, actin, ConA, and p62/SQSTM1 intensity features.

## How To Use

These files support compound-level image analysis, marker-state triage, and comparison between imaging and transcriptomic features. They are especially useful for p21, p62, and BRD4 protein-state analyses.