Interactive structural visualization of nanowells, devices, cell lines, and libraries
Each observation (row) in the dataset corresponds to a single **nanowell** rather than a single cell. Each nanowell measures **90 microns in diameter by 120 microns tall** and holds approximately **2 to 10 cells**. The transcriptomic profiles represent the pooled expression of the cells inside each nanowell.
Each physical device runs exactly one cell line. This eliminates cell mixing within a single microfluidic chip, enabling clean downstream sorting. However, multiple chemical libraries are pooled on each chip (ranging from 2 to 8 libraries per device).
The screen features a split between **One-Bead One-Compound (OBOC) combinatorial libraries** (testing 142.1k chemical precursor fragments across 353.3k wells) and **Named Control Compounds** (testing 78 fully synthesized target compounds across 311.3k wells).
Out of 49 devices, 24 devices contain no-compound controls (including capture-only control bead library `ZEL026-2` and water/vehicle controls like `ZIC005`). Only Device 11 lacks control beads entirely, profiling named control compounds exclusively.
| Device ID | Cell Line | Libraries Screened | Nanowell Count | Treatment Split |
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