Actives/actives_table_AKT1.csv

SMILES,Molecule Name,Target Name,Type
NC[C@H](Cc1cccc(F)c1)NC(=O)c4cc(Br)c(c2ccnc3[nH]ccc23)s4,CHEMBL523586_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(OC[C@@H](N)Cc1c[nH]c2ccccc12)c3)cc45,CHEMBL379300_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2NC(=O)C(c1ccco1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL573326_active,AKT1,Active
CC(C)(Cc1ccco1)C5C(=O)Nc6ccc(c4cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c4)cc56,CHEMBL210954_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(C#CC(C)(C)O)nc(O[C@@H](CCN)c2ccccc2)cc34,CHEMBL1099297_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(C#CC(C)(C)O)nc(OC[C@H](N)Cc2ccccc2)cc34,CHEMBL1098938_active,AKT1,Active
Cc4n[nH]c5cnc(c3cncc(OC[C@@H](N)Cc1c[nH]c2ccccc12)c3)cc45,CHEMBL376569_active,AKT1,Active
CCc3c[nH]c4ncnc(N2CC[C@](N)(CNC(=O)c1ccc(F)cc1F)C2)c34,CHEMBL1171647_active,AKT1,Active
NC4(COCc1ccc(Cl)cc1)CCN(c2ncnc3[nH]ccc23)CC4,CHEMBL597793_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2[nH]c(=O)\c(=C/c1ccc[nH]1)c2c3)c4)Cc5ccccc5,CHEMBL388311_active,AKT1,Active
Cc3n[nH]c4cnc(c2cncc(OC[C@@H](N)Cc1cccc(C(F)(F)F)c1)c2)cc34,CHEMBL226898_active,AKT1,Active
NC4(Cc1ccc(Cl)cc1)CCN(c2ncnc3[nH]ccc23)CC4,CHEMBL263664_active,AKT1,Active
NC[C@H](CC1CCCCC1)NC(=O)c4cc(Br)c(c2ccnc3[nH]ccc23)s4,CHEMBL470598_active,AKT1,Active
CCc3ncc(OC[C@@H](N)Cc1c[nH]c2ccccc12)cc3c5ccc4cnccc4c5,CHEMBL572908_active,AKT1,Active
Cc5n[nH]c6ccc(c3cc(OC[C@@H](N)Cc1c[nH]c2cc(F)ccc12)cnc3c4ccoc4)cc56,CHEMBL607374_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2NC(=O)C(c1cccs1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL572884_active,AKT1,Active
CC(C)(Cc1cccs1)C5C(=O)Nc6ccc(c4cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c4)cc56,CHEMBL209826_active,AKT1,Active
Cc3n[nH]c4ccc(c2cncc(OC[C@@H](N)Cc1cccc(I)c1)c2)cc34,CHEMBL229320_active,AKT1,Active
O=c7ccc(c6nnc(C5CCN(Cc4ccc(c2nc1cc[nH]c(=O)c1cc2c3ccccc3)cc4)CC5)[nH]6)c[nH]7,CHEMBL488428_active,AKT1,Active
Cc5n[nH]c6ncc(c3cc(OC[C@@H](N)Cc1c[nH]c2ccccc12)cnc3c4ccoc4)cc56,CHEMBL596072_active,AKT1,Active
Cc5n[nH]c6cnc(c3cc(OC[C@@H](N)Cc1c[nH]c2ccccc12)cnc3c4ccoc4)nc56,CHEMBL603197_active,AKT1,Active
Cc5n[nH]c6cnc(c3cc(OC[C@@H](N)Cc1c[nH]c2ccccc12)cnc3c4ccoc4)cc56,CHEMBL594933_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(C#CC(C)(C)O)ncc(OC[C@H]2CCCNC2)c34,CHEMBL494089_active,AKT1,Active
Cc5n[nH]c6ncc(c3cc(OC[C@@H](N)Cc1c[nH]c2ccccc12)cnc3c4ccoc4C)nc56,CHEMBL596583_active,AKT1,Active
COc2ccc1ccccc1c2C[C@H](N)COc5cncc(c4ccc3[nH]nc(C)c3c4)c5,CHEMBL210403_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2[nH]nc(c1ccc[nH]1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL572670_active,AKT1,Active
CC(C)(Cc1cc[nH]c1)C5C(=O)Nc6ccc(c4cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c4)cc56,CHEMBL210940_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2[nH]nc(c1cccs1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL576733_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2NC(=O)C(Cc1ccco1)c2c3)c4)Cc5ccccc5,CHEMBL575811_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2[nH]c(=O)/c(=C/c1ccco1)c2c3)c4)Cc5ccccc5,CHEMBL226849_active,AKT1,Active
N[C@H](COc4cnc(c1ccco1)c(c3ccc2cnccc2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL378843_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1NC(=O)C(F)(F)c1c2)c3)Cc4c[nH]c5ccccc45,CHEMBL577377_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2NC(=O)C(c1ccc[nH]1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL576348_active,AKT1,Active
CN[C@@H]1CC5O[C@@](C)([C@@H]1OC)n7c2ccccc2c8c3CNC(=O)c3c6c4ccccc4n5c6c78,CHEMBL162_active,AKT1,Active
CC(C)(Cc1ccc[nH]1)C5C(=O)Nc6ccc(c4cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c4)cc56,CHEMBL377603_active,AKT1,Active
NC[C@H](Cc1ccncc1)NC(=O)c4cc(Br)c(c2ccnc3[nH]ccc23)s4,CHEMBL498051_active,AKT1,Active
CCn2c(c1nonc1N)nc3c(C#CC(C)(C)O)nc(CN(C)C)cc23,CHEMBL1099290_active,AKT1,Active
N#Cc4c[nH]c5ncnc(N2CC1(CCNCC1)c3ccccc23)c45,CHEMBL258837_active,AKT1,Active
COc2cc1CCN(C(=O)CN(C)C)c1cc2Nc6nc(Nc4cccc3CNC(=O)c34)c5cc[nH]c5n6,CHEMBL517163_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2[nH]nc(C1CC1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL572907_active,AKT1,Active
Oc7nnc8c6cc(c1ccccc1)c(c5ccc(CN4CCC(c3n[nH]c(c2ccccn2)n3)CC4)cc5)nc6ccn78,CHEMBL506077_active,AKT1,Active
COc7ccc(c6nnc(C5CCN(Cc4ccc(c2nc1cc[nH]c(=O)c1cc2c3ccccc3)cc4)CC5)[nH]6)cn7,CHEMBL446966_active,AKT1,Active
NCC(C(=O)Nc3ccc(c1ccnc2[nH]ccc12)s3)c4ccccc4,CHEMBL512480_active,AKT1,Active
CNCC(NC(=O)c3cc(Br)c(c1ccnc2[nH]ccc12)s3)c4ccccc4,CHEMBL470410_active,AKT1,Active
Cc4n[nH]c5ccc(c2cc(OC[C@@H](N)Cc1ccccc1)cnc2c3cc(Cl)ccc3O)cc45,CHEMBL605733_active,AKT1,Active
N[C@H](CNc3nnc(c2ccc1cnccc1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1080569_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(C#CC(C)(C)O)nc(OC[C@H](N)c2ccccc2)cc34,CHEMBL1096634_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(C#CC(C)(C)O)ncc(OCC[C@@H](N)Cc2ccccc2)c34,CHEMBL523859_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(OC[C@@H](N)Cc2ccc1ccccc1c2)c3)cc45,CHEMBL210740_active,AKT1,Active
O=C7Cc6cc(N[C@H](COc3cncc(c2ccc1NC(=O)Cc1c2)c3)Cc4c[nH]c5ccccc45)ccc6N7,CHEMBL212566_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2NC(=O)C(C1CC1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL574269_active,AKT1,Active
CC(C)(CC1CC1)C5C(=O)Nc6ccc(c4cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c4)cc56,CHEMBL378827_active,AKT1,Active
Nc7nnc8c6cc(c1ccccc1)c(c5ccc(CN4CCC(n3cnc(c2ccccn2)c3)CC4)cc5)nc6ccn78,CHEMBL508794_active,AKT1,Active
O=C6N=CC=C7N=C(c4ccc(CN3CCC(c2n[nH]c(c1ccccn1)n2)CC3)cc4)C(c5ccccc5)=CC67,CHEMBL262341_active,AKT1,Active
O=C6NCCc7nc(c4ccc(CN3CCC(c2nnc(c1ccccn1)[nH]2)CC3)cc4)c(c5ccccc5)cc67,CHEMBL446134_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1cnccc1c2)c3)Cc5ccc4ccccc4c5,CHEMBL211018_active,AKT1,Active
CSc7ncc6cc(c1ccccc1)c(c5ccc(CN4CCC(c3nnc(c2ccccn2)[nH]3)CC4)cc5)nc6n7,CHEMBL254099_active,AKT1,Active
NC4(C(=O)NCc1ccc(Cl)cc1Cl)CCN(c2ncnc3[nH]ccc23)CC4,CHEMBL599849_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2[nH]nc(c1ccccc1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL574764_active,AKT1,Active
COc4ccc(O)c(C(=O)c3ccc(C(=O)N[C@@H]1CCCNCC1NC(=O)c2ccncc2)cc3)c4F,CHEMBL1202518_active,AKT1,Active
CSc7ncc6cc(c1ccccc1)c(c5ccc(CN4CCC(n2ncc3c(N)ncnc23)CC4)cc5)nc6n7,CHEMBL253693_active,AKT1,Active
O=c6[nH]ccc7nc(c4ccc(CN3CCC(c2nnc(c1cnccn1)[nH]2)CC3)cc4)c(c5ccccc5)cc67,CHEMBL444136_active,AKT1,Active
Clc3c[nH]c4ncnc(N2CCC1(CCNCC1)C2)c34,CHEMBL1173350_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1[nH]c(=O)oc1c2)c3)Cc4c[nH]c5ccccc45,CHEMBL575824_active,AKT1,Active
Oc7nc6ccc(N[C@H](COc3cncc(c2ccc1nc(O)sc1c2)c3)Cc4c[nH]c5ccccc45)cc6s7,CHEMBL209503_active,AKT1,Active
CSc7ncc6cc(c1ccccc1)c(c5ccc(CN4CCC(c3cc(c2ccncc2)[nH]n3)CC4)cc5)nc6n7,CHEMBL404554_active,AKT1,Active
N[C@H](CNc3ncc(c2ccc1cnccc1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081263_active,AKT1,Active
COc4ccc(O)c(C(=O)c3ccc(C(=O)O[C@@H]1CCCNCC1NC(=O)c2ccncc2)cc3)c4F,CHEMBL1204096_active,AKT1,Active
C6CN(Cc5ccc(c3nc2nc(n1ccnc1)ncc2cc3c4ccccc4)cc5)CCC6c8nnc(c7ccccn7)[nH]8,CHEMBL448926_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(C#CC(C)(C)O)ncc(OCCCNCCc2ccc(OC)cc2)c34,CHEMBL494060_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1[nH]c(=O)c(=O)c1c2)c3)Cc4c[nH]c5ccccc45,CHEMBL574268_active,AKT1,Active
C(Oc3cncc(c2cc1ccncc1s2)c3)[C@H](Cc4c[nH]c5ccccc45)Nc7cc6ccncc6s7,CHEMBL211281_active,AKT1,Active
Cc3n[nH]c4ccc(c2nnc(NC[C@@H](N)Cc1ccc(C(F)(F)F)cc1)s2)cc34,CHEMBL1080911_active,AKT1,Active
C5CN(Cc4ccc(c2nc1cccnc1cc2c3ccccc3)cc4)CCC5c7n[nH]c(c6ccccn6)n7,CHEMBL259753_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2NC(=O)C(c1ccccc1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL577379_active,AKT1,Active
CC(C)(Cc1ccccc1)C5C(=O)Nc6ccc(c4cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c4)cc56,CHEMBL210034_active,AKT1,Active
NCC(NC(=O)c4cc(C1CC1)c(c2ccnc3[nH]ccc23)s4)c5ccccc5,CHEMBL512858_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(C#CC(C)(C)O)nc(CN2CCCC2)cc34,CHEMBL1096290_active,AKT1,Active
CNc3nccc(c2ccc(C(=O)N[C@H](CN)Cc1ccc(Cl)cc1Cl)s2)n3,CHEMBL213618_active,AKT1,Active
Cc4n[nH]c5ncc(c2cc(OC[C@@H](N)Cc1ccccc1)c(N)nc2c3ccoc3C)nc45,CHEMBL594755_active,AKT1,Active
N[C@H](COc4cncc(c3cc2c(c1ccco1)n[nH]c2cn3)c4)Cc5ccccc5,CHEMBL375485_active,AKT1,Active
Oc7[nH]c6ccc(N[C@H](COc3cncc(c2ccc1[nH]c(O)c(N=O)c1c2)c3)Cc4c[nH]c5ccccc45)cc6c7N=O,CHEMBL376959_active,AKT1,Active
CC(C)(C)c4ccc(CC3(N)CCN(c1ccnc2[nH]ncc12)CC3)cc4,CHEMBL603675_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(OC[C@@H](N)Cc1csc2ccccc12)c3)cc45,CHEMBL263510_active,AKT1,Active
Cc4n[nH]c5cnc(c3cncc(OC[C@@H](N)Cc2cccc(OCC1CCNCC1)c2)c3)cc45,CHEMBL576372_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1cnccc1c2)c3)Cc4n[nH]c5ccccc45,CHEMBL211827_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(OC[C@@H](N)Cc2cccc(OCC1CCNCC1)c2)c3)cc45,CHEMBL226745_active,AKT1,Active
O=c6[nH]ccc7nc(c4ccc(CN3CCC(c2nnc(c1ncccn1)[nH]2)CC3)cc4)c(c5ccccc5)cc67,CHEMBL447114_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2NC(=O)C(c1ncc[nH]1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL579053_active,AKT1,Active
CC(C)(Cc1ncc[nH]1)C5C(=O)Nc6ccc(c4cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c4)cc56,CHEMBL210209_active,AKT1,Active
NC4(C(=O)NCc1ccc(Cl)cc1)CCN(c2ccnc3[nH]ccc23)CC4,CHEMBL599448_active,AKT1,Active
C5CN(Cc4ccc(c2nc1ccncc1cc2c3ccccc3)cc4)CCC5c7n[nH]c(c6ccccn6)n7,CHEMBL259967_active,AKT1,Active
N[C@H](COc3cncc(c2cnc1NC(=O)Cc1c2)c3)Cc4c[nH]c5ccccc45,CHEMBL575385_active,AKT1,Active
Oc7nc6ccc(N[C@H](COc3cncc(c2ccc1nc(O)oc1c2)c3)Cc4c[nH]c5ccccc45)cc6o7,CHEMBL209281_active,AKT1,Active
CC5(C)CCCN(c4ccc(O)c(C(=O)c3ccc(C(=O)N[C@@H]1CCCNC[C@H]1NC(=O)c2ccncc2)cc3)c4)C5,CHEMBL534916_active,AKT1,Active
Cc5n[nH]c6ccc(c3cc(OC[C@@H](N)Cc1c[nH]c2ncccc12)cnc3c4ccoc4)cc56,CHEMBL594310_active,AKT1,Active
NC6(c5ccc(c3nc2ccn1c(=O)[nH]nc1c2cc3c4ccccc4)cc5)CCC6,CHEMBL1079175_active,AKT1,Active
N[C@H](CNc3ncc(c2ccc1[nH]c(=O)oc1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081852_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(C#CC(C)(C)O)ncc(OC2CCNCC2)c34,CHEMBL522857_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(C#CC(C)(C)O)ncc(OCC2CCNC2)c34,CHEMBL494088_active,AKT1,Active
Cc3n[nH]c4ccc(c2cncc(NC[C@@H](N)Cc1ccccc1)c2)cc34,CHEMBL207338_active,AKT1,Active
N[C@H](COc4cncc(c3cc2c(c1ccccc1)n[nH]c2cn3)c4)Cc5ccccc5,CHEMBL226383_active,AKT1,Active
CSc6ncc5cc(c1ccccc1)c(c4ccc(CN3CCC(c2nnc(N)s2)CC3)cc4)nc5n6,CHEMBL403356_active,AKT1,Active
N[C@H](CNc3ncc(c2ccc1[nH]ncc1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081829_active,AKT1,Active
CSc6ncc5cc(c1ccccc1)c(c4ccc(CN3CCC(C(=O)Nc2ccncc2)CC3)cc4)nc5n6,CHEMBL252856_active,AKT1,Active
N[C@H](CNc2cncc(/C=C/c1ccncc1)c2)Cc3c[nH]c4ccccc34,CHEMBL203624_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2[nH]nc(c1nccs1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL574995_active,AKT1,Active
Cc5n[nH]c6ccc(c3cc(OC[C@@H](N)Cc1c[nH]c2cccnc12)cnc3c4ccoc4)cc56,CHEMBL605838_active,AKT1,Active
Cc4n[nH]c5ccc(c2cc(OC[C@@H](N)Cc1ccccc1)cnc2c3ccoc3)cc45,CHEMBL595709_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(C#CC(C)(C)O)ncc(OCC2CCNCC2)c34,CHEMBL521658_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2NC(=O)C(c1ccccn1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL573334_active,AKT1,Active
CC(C)(Cc1ccccn1)C5C(=O)Nc6ccc(c4cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c4)cc56,CHEMBL211774_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2NC(=O)C(c1cccnc1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL576386_active,AKT1,Active
CC(C)(Cc1cccnc1)C5C(=O)Nc6ccc(c4cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c4)cc56,CHEMBL211690_active,AKT1,Active
Cc5n[nH]c6ccc(c3cc(OC[C@@H](N)Cc1c[nH]c2ccccc12)cnc3c4ccoc4)nc56,CHEMBL596073_active,AKT1,Active
Cc5n[nH]c6ccc(c3cc(OC[C@@H](N)Cc1c[nH]c2ccncc12)cnc3c4ccoc4)cc56,CHEMBL593142_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(OC[C@@H](N)Cc2ccc1OC(F)(F)C(F)(F)Oc1c2)c3)cc45,CHEMBL226744_active,AKT1,Active
Cc4n[nH]c5cnc(c3cncc(OC[C@@H](N)Cc1cccc2OC(F)(F)Oc12)c3)cc45,CHEMBL576135_active,AKT1,Active
N[C@H](COc2cncc(/C=C/c1ccncc1)c2)Cc3c[nH]c4ccccc34,CHEMBL383541_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(OC[C@@H](N)Cc1cccc2OC(F)(F)Oc12)c3)cc45,CHEMBL227326_active,AKT1,Active
CNC(=O)Nc3ccc(CNc2c(C(=O)Nc1ccc(SC(F)(F)F)cc1)cnn2C)cn3,CHEMBL247797_active,AKT1,Active
CSc5ncc4cc(c1ccccc1)c(c3ccc(CNCCC(=O)c2ccccc2N)cc3)nc4n5,CHEMBL252456_active,AKT1,Active
Cc4n[nH]c5ccc(c2cc(OC[C@@H](N)Cc1ccccc1)cnc2c3ccc[nH]3)cc45,CHEMBL594749_active,AKT1,Active
Cn3c(=O)[nH]c4ccc(c2cnc(NC[C@@H](N)Cc1ccc(C(F)(F)F)cc1)s2)cc34,CHEMBL1082016_active,AKT1,Active
NCC(NC(=O)c3ccc(c1c[nH]c2ncccc12)s3)c4ccccc4,CHEMBL470192_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1NC(=O)Cc1c2)c3)Cc4ccccc4,CHEMBL226848_active,AKT1,Active
Cc3c[nH]c4ncnc(N2CCC(N)(CNC(=O)Oc1ccccc1)C2)c34,CHEMBL1171840_active,AKT1,Active
N[C@H](CNc3cc(c2ccc1cnccc1c2)no3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081104_active,AKT1,Active
Nc6ncnc7nc(c4ccc(CN3CCC(c2nc1ccc(F)cc1[nH]2)CC3)cc4)c(c5ccccc5)cc67,CHEMBL253457_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2[nH]nc(N1CCOCC1)c2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL578418_active,AKT1,Active
N[C@H](CNc3ncc(c2ccc1NC(=O)Cc1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081831_active,AKT1,Active
O=c2[nH]c1ccccc1n2C8CCN(Cc7ccc(c5nc4cc(c3nn[nH]n3)ccc4nc5c6ccccc6)cc7)CC8,CHEMBL408151_active,AKT1,Active
O=c2[nH]c1ccccc1n2C8CCN(Cc7ccc(c5nc4cc(n3cnnn3)ccc4nc5c6ccccc6)cc7)CC8,CHEMBL574289_active,AKT1,Active
C5CN(Cc4ccc(c2nc1cnccc1cc2c3ccccc3)cc4)CCC5c7n[nH]c(c6ccccn6)n7,CHEMBL259968_active,AKT1,Active
C[C@@]2(C(=O)Nc1ccc(F)nc1)CCCN2c6nc(Nc4cc(C3CC3)[nH]n4)c5cccn5n6,CHEMBL575448_active,AKT1,Active
CNC(=O)Nc4ccc(CNc1ncsc1C(=O)Nc3ccc2OC(F)(F)Oc2c3)cn4,CHEMBL247250_active,AKT1,Active
NCC(NC(=O)c3cc(c1c[nH]c2ncccc12)cs3)c4ccccc4,CHEMBL512305_active,AKT1,Active
N[C@H](CNc3ncc(c2ccc1[nH]c(=O)sc1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081853_active,AKT1,Active
CS(=O)(=O)N6CCN(Cc5cc4nc(c1cccc2[nH]ncc12)nc(N3CCOCC3)c4s5)CC6,CHEMBL521851_active,AKT1,Active
CSc5ncc4cc(c1ccccc1)c(c3ccc(CN2CCC(C(N)=O)CC2)cc3)nc4n5,CHEMBL252457_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(c2cc[nH]c2)ncc(OCCCN)c34,CHEMBL523057_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(c2ccc[nH]2)ncc(OCCCN)c34,CHEMBL493251_active,AKT1,Active
Cn2c(=O)n(c1ccc(C(C)(C)C#N)cc1)c5c2cnc4ccc(C#Cc3cccnc3)cc45,CHEMBL255592_active,AKT1,Active
O=c7ccc(c6cc(C5CCN(Cc4ccc(c2nc1ncccc1cc2c3ccccc3)cc4)CC5)n[nH]6)c[nH]7,CHEMBL260184_active,AKT1,Active
N[C@H](CNc3ncc(c2ccc1cncnc1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081296_active,AKT1,Active
NCC(NC(=O)c3cc(c1ccnc2[nH]ccc12)cs3)c4ccccc4,CHEMBL512672_active,AKT1,Active
N[C@H](CCc3cc(c2ccc1cnccc1c2)no3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081105_active,AKT1,Active
CNC(=O)Nc4ccc(CNc3c(C(=O)Nc2ccc1OC(F)(F)C(F)(F)Oc1c2)cnn3C)cn4,CHEMBL247619_active,AKT1,Active
C(Oc3cncc(c2ccc1nonc1c2)c3)[C@H](Cc4c[nH]c5ccccc45)Nc7ccc6nonc6c7,CHEMBL207217_active,AKT1,Active
Clc3c[nH]c4ncnc(N2CCc1nc[nH]c1C2)c34,CHEMBL259833_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(OC[C@@H](N)Cc2ccc1OCOc1c2)c3)cc45,CHEMBL227325_active,AKT1,Active
C5CN(Cc4ccc(c2nc1ncccc1cc2c3ccccc3)cc4)CCC5c7cc(c6ccccn6)[nH]n7,CHEMBL259982_active,AKT1,Active
O=C2C[C@H]1OCc4c([C@H]1O2)c(=O)c3ccccc3c4=O,CHEMBL475400_active,AKT1,Active
C5CN(Cc4ccc(c2nc1ncccc1cc2c3ccccc3)cc4)CCC5c7n[nH]c(c6ccccn6)n7,CHEMBL260670_active,AKT1,Active
CC(C#N)c5ccc(n3c(C)nc4cnc2ccc(C#Cc1cccnc1)cc2c34)cc5,CHEMBL270638_active,AKT1,Active
CSc5ncc4cc(c1ccccc1)c(c3ccc(CNCCc2nnc(N)s2)cc3)nc4n5,CHEMBL252455_active,AKT1,Active
NCC(NC(=O)c4cc(c1ccccc1)c(c2ccnc3[nH]ccc23)s4)c5ccccc5,CHEMBL470200_active,AKT1,Active
Cc4n[nH]c5ccc(c2cc(OC[C@@H](N)Cc1ccccc1)cnc2c3ccsc3)cc45,CHEMBL604060_active,AKT1,Active
Cn8nnc(c7ccc6nc(c1ccccc1)c(c5ccc(CN4CCC(n2c(O)nc3ccccc23)CC4)cc5)nc6c7)n8,CHEMBL180058_active,AKT1,Active
Cc2c[nH]c3ncnc(N1CCC(N)(CNC=O)C1)c23,CHEMBL1173384_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2cnc(C#Cc1ccccc1)cc2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL378211_active,AKT1,Active
O=C3C[C@H]2O[C@H](c1cccs1)c5c([C@H]2O3)c(=O)c4ccccc4c5=O,CHEMBL475401_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2cnc(c1ccco1)cc2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL210333_active,AKT1,Active
O=c2[nH]c1ccccc1n2C8CCN(Cc7ccc(c5nc4cc3nc[nH]c3cc4nc5c6ccccc6)cc7)CC8,CHEMBL258844_active,AKT1,Active
CSc6ncc5cc(c1ccccc1)c(c4ccc(CNCCc3n[nH]c(c2ccccc2)n3)cc4)nc5n6,CHEMBL252261_active,AKT1,Active
O=c2[nH]c1ccccc1n2C8CCN(Cc7ccc(c5nc4ccc(c3nn[nH]n3)cc4nc5c6ccccc6)cc7)CC8,CHEMBL271091_active,AKT1,Active
NCC(NC(=O)c4cc(c1cccnc1)c(c2ccnc3[nH]ccc23)s4)c5ccccc5,CHEMBL469357_active,AKT1,Active
NCC(NC(=O)c4cc(c1cn[nH]c1)c(c2ccnc3[nH]ccc23)s4)c5ccccc5,CHEMBL470202_active,AKT1,Active
O=c2[nH]c1ccccc1n2C8CCN(Cc7ccc(c5nc4ccc(n3cnnn3)cc4nc5c6ccccc6)cc7)CC8,CHEMBL574476_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1cnccc1c2)c3)Cc4csc5ccccc45,CHEMBL211865_active,AKT1,Active
CSc7ncc6cc(c1ccccc1)c(c5ccc(CN4CCC(c3nc(c2cccnc2)no3)CC4)cc5)nc6n7,CHEMBL404553_active,AKT1,Active
N[C@H](COc3cncc(/C=C/c2ccnc(NC1CC1)c2)c3)Cc4c[nH]c5ccccc45,CHEMBL203275_active,AKT1,Active
Cc2nc1ccccc1n2C7CCN(Cc6ccc(c4nc3ncnc(N)c3cc4c5ccccc5)cc6)CC7,CHEMBL402579_active,AKT1,Active
Cc3n[nH]c4ccc(c2cncc(OC[C@@H](N)CCCc1ccccc1)c2)cc34,CHEMBL211186_active,AKT1,Active
O=C3C[C@H]2O[C@H](COCc1ccccc1)c5c([C@H]2O3)c(=O)c4ccccc4c5=O,CHEMBL493359_active,AKT1,Active
C5CN(Cc4ccc(c2nc1ccccc1nc2c3ccccc3)cc4)CCC5c7cc(c6ccncc6)[nH]n7,CHEMBL261542_active,AKT1,Active
N[C@H](CNc3ncc(c2ccc1nnn(N)c1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081830_active,AKT1,Active
COc5cc4ncc3c(N)nc(c2cncc(OC[C@@H](N)Cc1cccc(Cl)c1)c2)cc3c4cc5OC,CHEMBL1096271_active,AKT1,Active
Cc4n[nH]c5ccc(c2cc(OC[C@@H](N)Cc1ccccc1)cnc2c3cccs3)cc45,CHEMBL594748_active,AKT1,Active
N[C@H](CNc2cnc(Cl)c(/C=C/c1ccncc1)c2)CC3CNc4ccccc34,CHEMBL381703_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(C#CC2CC2)ncc(OCCCN)c34,CHEMBL494882_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(c2ccoc2)ncc(OCCCN)c34,CHEMBL445180_active,AKT1,Active
Oc5ccc([C@@H]2O[C@@H]1CC(=O)O[C@@H]1c4c2c(=O)c3ccccc3c4=O)cc5,CHEMBL493360_active,AKT1,Active
CC(C)=c4c(=O)[nH]c5ccc(c3cncc(OC[C@@H](N)Cc1c[nH]c2ccccc12)c3)cc45,CHEMBL575384_active,AKT1,Active
OP(O)(=O)Oc1ccc(OP(O)(O)=O)c(OP(O)(O)=O)c1OP(O)(O)=O,CHEMBL595349_active,AKT1,Active
Nc6ncnc7nc(c4ccc(CN3CCC(n1c(=O)[nH]c2ccccc12)CC3)cc4)c(c5ccccc5)cc67,CHEMBL402199_active,AKT1,Active
O=c2[nH]c1ccccc1n2C8CCN(Cc7ccc(c5nc4cc3cn[nH]c3cc4nc5c6ccccc6)cc7)CC8,CHEMBL180231_active,AKT1,Active
N[C@H](CNc3nnc(c2ccc1cnccc1c2)o3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081119_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1cnccc1c2)c3)Cc5cnc4ccccc4c5,CHEMBL437122_active,AKT1,Active
Nc6n[nH]c7nc(c4ccc(CN3CCC(n1c(=O)[nH]c2ccccc12)CC3)cc4)c(c5ccccc5)cc67,CHEMBL270157_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1cnccc1c2)c3)Cc4ccccc4,CHEMBL210020_active,AKT1,Active
CSc5ncc4cc(c1ccccc1)c(c3ccc(CNCCc2cccnc2)cc3)nc4n5,CHEMBL403354_active,AKT1,Active
N[C@H](CNc3ncc(c2ccc1C(=O)NCc1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081029_active,AKT1,Active
CSc5ncc4cc(c1ccccc1)c(c3ccc(CNCCc2c[nH]cn2)cc3)nc4n5,CHEMBL252054_active,AKT1,Active
O=C3C[C@H]2O[C@H](c1ccsc1)c5c([C@H]2O3)c(=O)c4ccccc4c5=O,CHEMBL521638_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1[nH]c(=O)sc1c2)c3)Cc4c[nH]c5ccccc45,CHEMBL577134_active,AKT1,Active
O=C7Cc6ccc(N[C@H](COc3cncc(c2ccc1CC(=O)Nc1n2)c3)Cc4c[nH]c5ccccc45)nc6N7,CHEMBL211434_active,AKT1,Active
NCC(NCc3ccc(c1ccnc2[nH]ccc12)s3)c4ccccc4,CHEMBL469560_active,AKT1,Active
C/C(c1ccc[nH]1)=c2/c(=O)[nH]c3ccc(NC(N)=O)cc23,CHEMBL228654_active,AKT1,Active
Cc3n[nH]c4cn(=O)c(c2cncc(OC[C@@H](N)Cc1ccccc1)c2)cc34,CHEMBL226381_active,AKT1,Active
C5CN(Cc4ccc(c2nc1ncccc1cc2c3ccccc3)cc4)CCC5c7cc(c6ccncc6)[nH]n7,CHEMBL261540_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2cnc(c1ccncc1)cc2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL209564_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(OC[C@@H](N)Cc2cccc(c1ccccc1)c2)c3)cc45,CHEMBL389468_active,AKT1,Active
Nc6ncnc7nc(c4ccc(CN3CCC(n1cnc2c(N)ncnc12)CC3)cc4)c(c5ccccc5)cc67,CHEMBL255360_active,AKT1,Active
CSc5ncc4cc(c1ccccc1)c(c3ccc(CNCCCn2ccnc2)cc3)nc4n5,CHEMBL252259_active,AKT1,Active
CSc5ncc4cc(c1ccccc1)c(c3ccc(CNCCc2nc[nH]n2)cc3)nc4n5,CHEMBL252055_active,AKT1,Active
N[C@H](CNc3ncc(c2ccc1nnccc1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081974_active,AKT1,Active
N[C@H](COc2cncc(/C=C/c1ccncc1)c2)Cc3csc4ccccc34,CHEMBL206183_active,AKT1,Active
N[C@H](COc2cncc(/C=C/c1ccncc1)c2)Cc4ccc3ccccc3c4,CHEMBL381328_active,AKT1,Active
N[C@H](COc3cncc(/C=C/c2ccnc(NCc1ccccc1)c2)c3)Cc4c[nH]c5ccccc45,CHEMBL381610_active,AKT1,Active
Oc7nc6cc(N[C@H](COc3cncc(c2ccc1[nH]c(O)nc1c2)c3)Cc4c[nH]c5ccccc45)ccc6[nH]7,CHEMBL209231_active,AKT1,Active
C[C@H]5O[C@@H](c4ccc3c(=O)c2[C@H]1OC(=O)C[C@H]1O[C@H](C)c2c(=O)c3c4)C[C@@H](N(C)C)[C@@H]5O,CHEMBL475838_active,AKT1,Active
Cc4nnc(c1ccccc1Nc2ncnc3[nH]ccc23)[nH]4,CHEMBL428963_active,AKT1,Active
N[C@H](COc5cncc(c4ccc3NC(=O)C(c1c[nH]c2ccccc12)c3c4)c5)Cc6c[nH]c7ccccc67,CHEMBL573096_active,AKT1,Active
CC(C)(Cc1c[nH]c2ccccc12)C6C(=O)Nc7ccc(c5cncc(OC[C@@H](N)Cc3c[nH]c4ccccc34)c5)cc67,CHEMBL210237_active,AKT1,Active
NCCNC(=O)c3cc(Br)c(c1ccnc2[nH]ccc12)s3,CHEMBL470409_active,AKT1,Active
COc4ccc(O)c(C(=O)c3ccc(/C=C/[C@@H]1CCCNC[C@H]1NC(=O)c2ccncc2)cc3)c4F,CHEMBL1204095_active,AKT1,Active
OC(=O)c7ccc6nc(c1ccccc1)c(c5ccc(CN4CCC(n2c(=O)[nH]c3ccccc23)CC4)cc5)nc6c7,CHEMBL273160_active,AKT1,Active
C(NCc4ccc(c2ncc(c1nn[nH]n1)cc2c3ccccc3)cc4)c6ccc(c5csnn5)cc6,CHEMBL425155_active,AKT1,Active
N[C@H](COc3cncc(c2cc1ccncc1s2)c3)Cc4c[nH]c5ccccc45,CHEMBL516429_active,AKT1,Active
O=c7[nH]c6ccc(N[C@H](COc3cncc(c2ccc1[nH]c(=O)c(=O)c1c2)c3)Cc4c[nH]c5ccccc45)cc6c7=O,CHEMBL377687_active,AKT1,Active
N[C@H](CNc4nnc(c3ccc2[nH]nc(C1CC1)c2c3)s4)Cc5ccc(C(F)(F)F)cc5,CHEMBL1081437_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(OC[C@@H](N)Cc2cnc1ccccc1c2)c3)cc45,CHEMBL379868_active,AKT1,Active
N[C@H](COc2cncc3nc(c1ccncc1)ccc23)Cc4c[nH]c5ccccc45,CHEMBL207496_active,AKT1,Active
CSc5ncc4cc(c1ccccc1)c(c3ccc(CNCCc2nccs2)cc3)nc4n5,CHEMBL252056_active,AKT1,Active
N[C@H](CCc2cnc(Cl)c(/C=C/c1ccncc1)c2)Cc3c[nH]c4ccccc34,CHEMBL203329_active,AKT1,Active
NC3CCCN(c1ncnc2[nH]cc(Cl)c12)C3,CHEMBL1173349_active,AKT1,Active
CCn3c(c1nonc1N)nc4cncc(CNC2CCNCC2)c34,CHEMBL188434_active,AKT1,Active
N[C@H](COc2cncc(CCc1ccncc1)c2)Cc3c[nH]c4ccccc34,CHEMBL575646_active,AKT1,Active
N[C@H](CNc3cncc(Oc1cccc2cnccc12)c3)Cc4c[nH]c5ccccc45,CHEMBL206732_active,AKT1,Active
N[C@H](COc2cncc(C#Cc1ccncc1)c2)Cc3c[nH]c4ccccc34,CHEMBL206208_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1nnccc1c2)c3)Cc4c[nH]c5ccccc45,CHEMBL573394_active,AKT1,Active
CSc4ncc3cc(c1ccccc1)c(c2ccc(CNCCC(N)=O)cc2)nc3n4,CHEMBL276130_active,AKT1,Active
CC(=O)Nc4ccc(c3cncc(OC[C@@H](N)Cc1c[nH]c2ccccc12)c3)cc4,CHEMBL381785_active,AKT1,Active
Cn1cccc1c4n[nH]c5cnc(c3cncc(OC[C@@H](N)Cc2ccccc2)c3)cc45,CHEMBL375486_active,AKT1,Active
Cc3n[nH]c4ccc(c2cncc(OC[C@@H](N)c1ccccc1)c2)cc34,CHEMBL378870_active,AKT1,Active
Fc7ccc6[nH]c(C5CCN(Cc4ccc(c2ncc(c1nn[nH]n1)cc2c3ccccc3)cc4)CC5)nc6c7,CHEMBL181730_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(SC[C@@H](N)Cc1c[nH]c2ccccc12)c3)cc45,CHEMBL378759_active,AKT1,Active
N[C@H](COc2cncc(c1ccncc1)c2)Cc3c[nH]c4ccccc34,CHEMBL208199_active,AKT1,Active
C5CN(Cc4ccc(c2nc1ncccc1cc2c3ccccc3)cc4)CCC5c7cc(c6cccnc6)[nH]n7,CHEMBL407733_active,AKT1,Active
NCC(CNc3ccc(c1ccnc2[nH]ccc12)s3)c4ccccc4,CHEMBL469561_active,AKT1,Active
Clc6nc(c4ccc(CN3CCC(n1c(=O)[nH]c2ccccc12)CC3)cc4)c(c5ccccc5)cc6C#N,CHEMBL270388_active,AKT1,Active
CC1(C)CCCNC1c5ccc(O)c(C(=O)c4ccc(C(=O)N[C@@H]2CCCNC[C@H]2NC(=O)c3ccncc3)cc4)c5F,CHEMBL536485_active,AKT1,Active
N[C@H](CNc3cncc(Nc1cccc2cnccc12)c3)Cc4c[nH]c5ccccc45,CHEMBL205994_active,AKT1,Active
N[C@H](COc2cncc(/C=C/c1ccncc1)c2)C(c3ccccc3)c4ccccc4,CHEMBL203434_active,AKT1,Active
Cn1nnnc1c7cnc(c5ccc(CN4CCC(n2c(O)nc3ccccc23)CC4)cc5)c(c6ccccc6)c7,CHEMBL182101_active,AKT1,Active
O=c2[nH]c1ccccc1n2C7CCN(Cc6ccc(c4ncc(c3nnn[nH]3)cc4c5ccccc5)cc6)CC7,CHEMBL270847_active,AKT1,Active
N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc4cncc(/C=C/c3ccncc3)c4,CHEMBL205415_active,AKT1,Active
NCC(c1ccccc1)c3cncc(/C=C/c2ccncc2)c3,CHEMBL383254_active,AKT1,Active
Cc3n[nH]c4ccc(c2cncc(OCC[C@@H](N)Cc1ccccc1)c2)cc34,CHEMBL211084_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(OC[C@@H](N)Cc2cccc(OCCC1CCNCC1)c2)c3)cc45,CHEMBL388310_active,AKT1,Active
O=C3C[C@H]2OC1(CCCC1)c5c([C@H]2O3)c(=O)c4ccccc4c5=O,CHEMBL504537_active,AKT1,Active
N[C@H](COc3cnc2ccc(c1ccncc1)cc2c3)Cc4c[nH]c5ccccc45,CHEMBL206819_active,AKT1,Active
COc6cc5ncc4c(N)nc(c3cncc(OC[C@@H](N)Cc1c[nH]c2ccccc12)c3)cc4c5cc6OC,CHEMBL1095612_active,AKT1,Active
N[C@H](COc4cncc(c3ccc2cnc(c1ccccc1)cc2c3)c4)Cc5c[nH]c6ccccc56,CHEMBL210544_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1ncccc1c2)c3)Cc4c[nH]c5ccccc45,CHEMBL573393_active,AKT1,Active
CC[C@@H](N)COc4cncc(c3cc2c(cnc1cc(OC)c(OC)cc12)c(N)n3)c4,CHEMBL1094320_active,AKT1,Active
N[C@H](COc2cncc(/C=C/c1ccncc1)c2)Cc3cccc(C#N)c3,CHEMBL205410_active,AKT1,Active
N[C@H](COc2cncc(/C=C/c1ccncc1)c2)Cc3cccc4ccccc34,CHEMBL205871_active,AKT1,Active
N[C@H](COc3cncc(c1cccc2cnccc12)c3)Cc4c[nH]c5ccccc45,CHEMBL581848_active,AKT1,Active
CCn3c(c1nonc1N)nc4c(c2ccccc2)ncc(OCCCN)c34,CHEMBL493250_active,AKT1,Active
CCn3c(c1nonc1N)nc4cncc(C(=O)N2CC[C@@H](N)C2)c34,CHEMBL523695_active,AKT1,Active
COc4ccc(O)c(C(=O)c3ccc(CO[C@@H]1CCCNCC1NC(=O)c2ccncc2)cc3)c4F,CHEMBL1202525_active,AKT1,Active
Oc2nc1ccccc1n2C7CCN(Cc6ccc(c4nc3ccccc3cc4c5ccccc5)cc6)CC7,CHEMBL359864_active,AKT1,Active
Cc3n[nH]c4ccc(c2cncc(OC[C@@H](N)CC1CCCCC1)c2)cc34,CHEMBL212259_active,AKT1,Active
CC2=NN(C(=O)c1ccc(Cl)cc1)C(=O)C2N=Nc4ccc(S(=O)(=O)Nc3ncccn3)cc4,CHEMBL603852_active,AKT1,Active
N[C@H](CNc3cnc(c2ccc1cnccc1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081425_active,AKT1,Active
N[C@H](CNc4nnc(c3ccc2[nH]nc(c1ccccc1)c2c3)s4)Cc5cccc(C(F)(F)F)c5,CHEMBL1081438_active,AKT1,Active
CCC[C@H]1O[C@H](CC(O)=O)Cc3c1c(=O)c2c(O)cccc2c3=O,CHEMBL444165_active,AKT1,Active
Nc2ccc(S(=O)(=O)Nc1nncs1)cc2,CHEMBL286737_active,AKT1,Active
N[C@H](CNc3ncc(c2ccc1onc(N)c1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1081660_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1cnccc1c2)c3)c4ccccc4,CHEMBL207373_active,AKT1,Active
C5CN(Cc4ccc(c2nc1ncccc1cc2c3ccccc3)cc4)CCC5c7cc(c6ccccc6)[nH]n7,CHEMBL429703_active,AKT1,Active
C(Oc3cncc(c2cc1cnccc1s2)c3)[C@H](Cc4c[nH]c5ccccc45)Nc7cc6cnccc6s7,CHEMBL211224_active,AKT1,Active
CCn3c(c1nonc1N)nc4cncc(C(=O)N2CCNCC2)c34,CHEMBL493066_active,AKT1,Active
CCn3c(c1nonc1N)nc4cncc(C(=O)NC2CCNCC2)c34,CHEMBL494662_active,AKT1,Active
Cc3c[nH]c4ncnc(N2CC[C@H](NS(=O)(=O)c1ccccc1)C2)c34,CHEMBL1173697_active,AKT1,Active
N[C@H](CNc3ncc(c2ccc1cn[nH]c1c2)s3)Cc4ccc(C(F)(F)F)cc4,CHEMBL1079625_active,AKT1,Active
CCn3c(c1nonc1N)nc4cncc(C(=O)NC2CCCNC2)c34,CHEMBL493067_active,AKT1,Active
CC(C)(CC1CCCN1)C5C(=O)Nc6ccc(c4cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c4)cc56,CHEMBL207139_active,AKT1,Active
N[C@@H](Cc1cccc2ccccc12)C(=O)Nc4cncc(/C=C/c3ccncc3)c4,CHEMBL383527_active,AKT1,Active
N[C@H](COc3cncc(c2ccc1cnccc1c2)c3)CC4CCCCC4,CHEMBL209638_active,AKT1,Active
Cc3c[nH]c4ncnc(N2CC[C@H](NC(=O)Nc1ccccc1)C2)c34,CHEMBL1173304_active,AKT1,Active
Cc3c[nH]c4ncnc(N2CC[C@H](NC(=O)c1ccccc1)C2)c34,CHEMBL1170238_active,AKT1,Active
Cc4n[nH]c5cnc(c3cncc(OC[C@@H](N)Cc2cccc(OCCN1CCOCC1)c2)c3)cc45,CHEMBL575428_active,AKT1,Active
Cc4n[nH]c5ccc(c3cncc(OC[C@@H](N)Cc2cccc(OCCN1CCOCC1)c2)c3)cc45,CHEMBL415220_active,AKT1,Active
Cn3cc(C(CN)Oc2cncc(/C=C/c1ccncc1)c2)c4ccccc34,CHEMBL574290_active,AKT1,Active
Cc6nc(c4ccc(CN3CCC(n1c(=O)[nH]c2ccccc12)CC3)cc4)c(c5ccccc5)[nH]c6=O,CHEMBL178397_active,AKT1,Active
Cn3cc(C(CN)c2cncc(/C=C/c1ccncc1)c2)c4ccccc34,CHEMBL202937_active,AKT1,Active
CSc5ncc4cc(c1ccccc1)c(c3ccc(CNCCCN2CCN(C)CC2)cc3)nc4n5,CHEMBL251860_active,AKT1,Active
Cc4n[nH]c5ccc(c2cc(OC[C@@H](N)Cc1ccccc1)cnc2c3ccco3)cc45,CHEMBL595708_active,AKT1,Active
Fc6ccc5[nH]c(C4CCN(Cc3ccc(c1ncc(C#N)cc1c2ccccc2)cc3)CC4)nc5c6,CHEMBL368010_active,AKT1,Active
COc6cc(c5ccc4c(=O)[nH]c3cc(CC(=O)Nc2ccc(N1CCOCC1)cc2)ccc3[nH]c4c5)ccc6N,CHEMBL395080_active,AKT1,Active