Sanitized/Actives/actives_table_KIF11_sanitized.csv

SMILES,Molecule Name,Target Name,Type
CC(=O)C1=NN(c2cc(C)ccc2F)C[C@@]1(CCCN(C)C)c1ccccc1,CHEMBL247044_active,KIF11,Active
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN1CCOCC1)c1ccccc1,CHEMBL398478_active,KIF11,Active
N[C@H](C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1)C1CC1,CHEMBL206115_active,KIF11,Active
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN)c1ccccc1,CHEMBL250127_active,KIF11,Active
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(C[C@H](F)CN)c1ccccc1,CHEMBL400042_active,KIF11,Active
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN)c1ccccc1,CHEMBL241754_active,KIF11,Active
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN1CCC(=O)N(C)CC1)c1ccccc1,CHEMBL251142_active,KIF11,Active
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CC[C@H](F)C1)c1ccccc1,CHEMBL240704_active,KIF11,Active
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CC2CCC1C2)c1ccccc1,CHEMBL398396_active,KIF11,Active
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1C[C@H]2C[C@@H]1CO2)c1ccccc1,CHEMBL240497_active,KIF11,Active
CC(=O)C1=NN2c3cc(Cl)ccc3OC[C@H]2[C@@]1(CCCN1CCN(C(C)=O)CC1)c1ccccc1,CHEMBL250126_active,KIF11,Active
CC(=O)C1=NN2c3cc(C)ccc3OC[C@H]2[C@@]1(CCCN1CCOCC1)c1ccccc1,CHEMBL399378_active,KIF11,Active
CC(=O)C1=NN2c3cc(Cl)ccc3OC[C@H]2[C@@]1(CCCN(C)C)c1ccccc1,CHEMBL429553_active,KIF11,Active
Cc1ccc(C(=O)N(CCCN)[C@@H](c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1F,CHEMBL436624_active,KIF11,Active
CCCC(=O)N1CCc2c([nH]c3ccc(C)cc23)C1c1c[nH]c2ccccc12,CHEMBL1163881_active,KIF11,Active
CC(C)[C@H](N)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1,CHEMBL381526_active,KIF11,Active
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CC2CC1CO2)c1ccccc1,CHEMBL246603_active,KIF11,Active
CC(C)(C)[C@H](O)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1,CHEMBL262736_active,KIF11,Active
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CCCC1)c1ccccc1,CHEMBL427688_active,KIF11,Active
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN(C)C)c1ccccc1,CHEMBL392148_active,KIF11,Active
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN1CCNC(=O)CC1)c1ccccc1,CHEMBL438876_active,KIF11,Active
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN1CCN(C(C)=O)CC1)c1ccccc1,CHEMBL250125_active,KIF11,Active
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN(C)C)c1ccccc1,CHEMBL250328_active,KIF11,Active
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CC(F)C1)c1ccccc1,CHEMBL240498_active,KIF11,Active
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CCOCC1)c1ccccc1,CHEMBL239415_active,KIF11,Active
CC(=O)C1=NN2c3cc(Cl)ccc3OC[C@H]2C1(CCCN1CCOCC1)c1ccccc1,CHEMBL250533_active,KIF11,Active
O=C1CCc2cc(-c3ccc(C(F)(F)F)cc3)ccc2N1,CHEMBL1222153_active,KIF11,Active
N[C@H](C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1)C1CC1,CHEMBL204459_active,KIF11,Active
CC(=O)C1=NN(c2cc(C)ccc2F)CC1(CCCN1CCN(C(C)=O)CC1)c1ccccc1,CHEMBL443490_active,KIF11,Active
CC(C)c1ccc2c(c1)[C@H]1O[C@@H](CNS(=O)(=O)CCCN(C)C)CC[C@H]1[C@H](c1ccccc1)N2,CHEMBL1084143_active,KIF11,Active
CN(C)CCS(=O)(=O)NC[C@H]1CC[C@@H]2[C@H](O1)c1cc(Cl)cc(F)c1N[C@H]2c1ccccc1,CHEMBL1096003_active,KIF11,Active
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN(C)C)c1ccccc1,CHEMBL246604_active,KIF11,Active
CN(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@@]1(CCCN)c1ccccc1,CHEMBL395332_active,KIF11,Active
CN(C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1)C1CCNCC1,CHEMBL205437_active,KIF11,Active
CC(=O)N1CCN(CCC[C@@]2(c3ccccc3)CC(c3cc(F)ccc3F)=NN2C(C)=O)CC1,CHEMBL239414_active,KIF11,Active
O=C([C@@H](O)C1CC1)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1,CHEMBL377596_active,KIF11,Active
CC(=O)C1=NN(c2cc(F)ccc2F)C[C@@]1(CCCN1CCN(C(C)=O)CC1)c1ccccc1,CHEMBL249882_active,KIF11,Active
CNC[C@H]1CC[C@@H]2[C@H](O1)c1cc(Br)cc(F)c1N[C@H]2c1ccccc1,CHEMBL1082248_active,KIF11,Active
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1F,CHEMBL243669_active,KIF11,Active
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CCN(C(C)=O)CC1)c1ccccc1,CHEMBL248400_active,KIF11,Active
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CCCC1)c1ccccc1,CHEMBL246422_active,KIF11,Active
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CCC(F)(F)C1)c1ccccc1,CHEMBL400041_active,KIF11,Active
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN(C)Cc1cc(C)no1)c1ccccc1,CHEMBL246000_active,KIF11,Active
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CCOCC1)c1ccccc1,CHEMBL246001_active,KIF11,Active
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN1CCNCC1)c1ccccc1,CHEMBL401476_active,KIF11,Active
CNC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(C)(C)C)ccc1N[C@H]2c1cccs1,CHEMBL1077227_active,KIF11,Active
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CC(F)C1)c1ccccc1,CHEMBL248244_active,KIF11,Active
CN(C(=O)N1CC(c2cc(F)ccc2F)=CC1c1cccc(O)c1)C1CCNCC1,CHEMBL206249_active,KIF11,Active
FC(F)(F)c1ccc2c(c1)[C@H]1O[C@@H](Cn3cncn3)CC[C@H]1[C@H](c1ccccc1)N2,CHEMBL1093088_active,KIF11,Active
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1,CHEMBL390629_active,KIF11,Active
NCCN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1,CHEMBL1163678_active,KIF11,Active
NC(=O)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1F,CHEMBL243668_active,KIF11,Active
CCc1ccc2[nH]c3c(c2c1)CCN(C(=O)CCN)C3c1cccc(O)c1,CHEMBL590124_active,KIF11,Active
CNC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C3CC3)ccc1N[C@H]2c1ccccc1,CHEMBL1083836_active,KIF11,Active
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CCS(=O)(=O)CC1)c1ccccc1,CHEMBL401006_active,KIF11,Active
NCCN(C[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(F)(F)F)ccc1N[C@H]2c1ccccc1)c1ccccc1,CHEMBL1093087_active,KIF11,Active
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)CCN)C3c1cccc(O)c1,CHEMBL590123_active,KIF11,Active
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1cccs1)N2,CHEMBL1078998_active,KIF11,Active
NCCCC1(c2ccccc2)CC(c2cc(F)ccc2F)=NN1C(=O)N1CCCC1,CHEMBL382790_active,KIF11,Active
NS(=O)(=O)Nc1ccc(-c2ccc3c(c2)OC(F)(F)O3)cc1,CHEMBL242181_active,KIF11,Active
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)c(F)c2)cn1,CHEMBL470767_active,KIF11,Active
NCCC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1c[nH]c2ccccc12,CHEMBL1164477_active,KIF11,Active
CCC(c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1)N(CCCN(C)C)C(=O)c1ccc(Br)cc1,CHEMBL1164552_active,KIF11,Active
CC(=O)N1CCC(N(C)C(=O)N2CC(c3cc(F)ccc3F)=C[C@H]2c2ccccc2)CC1,CHEMBL208422_active,KIF11,Active
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)c1ccc(N)cc1)C3c1cccc(O)c1,CHEMBL1163584_active,KIF11,Active
CC(=O)N1CCc2c([nH]c3ccc(C)cc23)C1c1c[nH]c2ccccc12,CHEMBL1164373_active,KIF11,Active
NCCCC1(c2ccccc2)CC(c2cc(F)ccc2F)=NN1C(=O)N1CCC1,CHEMBL210264_active,KIF11,Active
Cc1ccc(C(=O)N(CCCN)C(c2nn3c(Cl)ccc3c(=O)n2Cc2ccccc2)C2CC2)cc1,CHEMBL213184_active,KIF11,Active
CCC(c1nn2c(Cl)ccc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1,CHEMBL213686_active,KIF11,Active
CCC(c1nn2c(Cl)ccc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(Cl)cc1,CHEMBL209815_active,KIF11,Active
Cc1ccc(C(=O)N(CCN)C[C@H]2CC[C@@H]3[C@H](O2)c2cc(C(F)(F)F)ccc2N[C@H]3c2ccccc2)cc1,CHEMBL1084431_active,KIF11,Active
NS(=O)(=O)Nc1ccc(-c2ccc3c(c2)OC(F)(F)C(F)(F)O3)cc1,CHEMBL397673_active,KIF11,Active
CCC(c1nn2ccc(Cl)c2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1,CHEMBL535161_active,KIF11,Active
Nc1ccc(C(=O)N2CCc3c([nH]c4ccc(Cl)cc34)C2c2cccc(O)c2)cc1,CHEMBL1164476_active,KIF11,Active
NCCCC1(c2ccccc2)CC(c2cc(F)ccc2F)=NN1C(=O)N1CCCCC1,CHEMBL381985_active,KIF11,Active
NCCCCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@@H](c3cccc(O)c3)N2C1=O,CHEMBL399296_active,KIF11,Active
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCNCc1ccccc1)c1ccccc1,CHEMBL207993_active,KIF11,Active
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)CCN1CCCCC1)C3c1cccc(O)c1,CHEMBL594458_active,KIF11,Active
Cc1ccc(C(=O)N(CCCN)C(c2nn3ccc(Cl)c3c(=O)n2Cc2ccccc2)C2CC2)cc1,CHEMBL380294_active,KIF11,Active
CCN(CC)C(=O)c1c(NC(=O)c2cccs2)sc2c1CC(C)CC2,CHEMBL388313_active,KIF11,Active
CC1=C(C(=O)c2ccccc2)[C@@H](c2cccc(O)c2)NC(=S)N1C,CHEMBL522806_active,KIF11,Active
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCN1CC2C=CC1C2)c1ccccc1,CHEMBL378497_active,KIF11,Active
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccsc1)N2,CHEMBL1084115_active,KIF11,Active
NCCCC1(c2ccccc2)CC(c2cc(F)ccc2F)=NN1C(=O)N1CCOCC1,CHEMBL210741_active,KIF11,Active
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O,CHEMBL392695_active,KIF11,Active
COc1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1,CHEMBL392369_active,KIF11,Active
CC1(C)CC(=O)C2=C(C1)NC(=S)NC2c1cccc(O)c1,CHEMBL394880_active,KIF11,Active
CC1(C)CC(=O)C2=C(C1)NC(=S)N[C@H]2c1cccc(O)c1,CHEMBL1213955_active,KIF11,Active
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc(C(F)(F)F)cc1)C(=O)O,CHEMBL232133_active,KIF11,Active
NCCC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1C1CCCCC1,CHEMBL591330_active,KIF11,Active
CC(C)(C)c1ccc2[nH]c3ccccc3c2c1,CHEMBL1170621_active,KIF11,Active
FC(F)(F)c1ccc2c(c1)[nH]c1ccccc12,CHEMBL1173704_active,KIF11,Active
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccc(Cl)s1)N2,CHEMBL1084116_active,KIF11,Active
CC(C)(C)c1ccc2c(c1)[nH]c1ccccc12,CHEMBL1173703_active,KIF11,Active
Cc1ccc2c(c1C)CN(C(=O)N(C)C)CC2c1cccc(O)c1,CHEMBL380367_active,KIF11,Active
CN(C)C(=O)N1Cc2cc(I)ccc2C(c2cccc(O)c2)C1,CHEMBL382364_active,KIF11,Active
NS(=O)(=O)Nc1ccc(-c2ccc3c(c2)C(F)(F)OC(F)(F)O3)cc1,CHEMBL244329_active,KIF11,Active
NC(=O)Nc1ccc(-c2ccc(C3(C(F)(F)F)N=N3)cc2)cc1,CHEMBL1222255_active,KIF11,Active
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCNC(=O)c1ccccn1)c1ccccc1,CHEMBL425420_active,KIF11,Active
CC(C)(C)c1cccc(-c2ccncc2)c1,CHEMBL449439_active,KIF11,Active
CCN(CC)C(=O)c1c(NC(=O)c2cccs2)sc2c1CCCC2,CHEMBL228369_active,KIF11,Active
CC1(C)Oc2ccc(-c3ccc(NS(N)(=O)=O)cc3)cc2O1,CHEMBL242182_active,KIF11,Active
CC1=C(C(=O)c2ccccc2)[C@H](c2cccc(O)c2)NC(=S)N1C,CHEMBL491384_active,KIF11,Active
CSc1ccc(Nc2nc3cc(C(N)=O)ccc3n2Cc2ccccc2C(F)(F)F)cc1,CHEMBL561696_active,KIF11,Active
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1nccs1)N2,CHEMBL1084391_active,KIF11,Active
O=C(Nc1sc2c(c1C(=O)N1CCCCC1)CCCC2)c1cccs1,CHEMBL390303_active,KIF11,Active
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCNC(=O)c1ncc[nH]1)c1ccccc1,CHEMBL209310_active,KIF11,Active
CN(C)C(=O)N1Cc2c(ccc3c2OCC3)C(c2cccc(O)c2)C1,CHEMBL381794_active,KIF11,Active
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCNC(=O)c1c[nH]cn1)c1ccccc1,CHEMBL208864_active,KIF11,Active
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cn2)cc1,CHEMBL470776_active,KIF11,Active
Oc1cccc(C2c3[nH]c4ccc(Cl)cc4c3CCN2Cc2ccccc2)c1,CHEMBL1163892_active,KIF11,Active
CCCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@@H](c3cccc(O)c3)N2C1=O,CHEMBL252340_active,KIF11,Active
O=C(CC1CCNCC1)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1,CHEMBL590855_active,KIF11,Active
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCNC(=O)c1ccccc1)c1ccccc1,CHEMBL208346_active,KIF11,Active
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)C1CCCN(C)C1)C3c1cccc(O)c1,CHEMBL594459_active,KIF11,Active
Cc1ccc(C(=O)N(CCC(N)=O)C(c2nn3c(Cl)ccc3c(=O)n2Cc2ccccc2)C2CC2)cc1,CHEMBL380186_active,KIF11,Active