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slow cognitive decline is bringing some hope to the fight against dementia, but critics say it\u2019s too soon to celebrate.\nLecanemab, the drug being tested by Eisai Co. Ltd. and Biogen Inc., was found to have a modest benefit to patients in a Phase 3 study. It has not been approved by the Food and Drug Administration.\nThe data, published in the New England Journal of Medicine at the end of November, showed that the drug moderately slowed the progression of Alzheimer\u2019s in patients in the earliest stages of the disease. But the study also found that lecanemab may pose risks to people who take blood thinners.\n\u201cIt\u2019s not a breakthrough. It\u2019s a very minimal benefit with questionable concerns,\u201d said Constantine Lyketsos, associate director of the Alzheimer\u2019s Disease Research Center at Johns Hopkins University School of Medicine. \u201cIt\u2019s not exciting.\u201d\n\u201cFor the current victims and their families, I don\u2019t think it offers hope,\u201d said Richard Besdine, a professor of medicine and director of the geriatrics division at Brown University.\nAlso read:\u00a05 things to know about the new Alzheimer\u2019s drug \u2014 including why it may be risky for people who take blood thinners\nOthers in the Alzheimer\u2019s field cheered the development, despite the modest benefit.\n\u201cThese peer-reviewed, published results show lecanemab will provide patients more time to participate in daily life and live independently. It could mean many months more of recognizing their spouse, children and grandchildren,\u201d the Alzheimer\u2019s Association said in a statement Nov. 29, after the results were reported.\n\u201cTreatments that deliver tangible benefits to those living with mild cognitive impairment (MCI) due to Alzheimer\u2019s and early Alzheimer\u2019s dementia are as valuable as treatments that extend the lives of those with other terminal diseases,\u201d the association said.\nThe trial results come as Alzheimer\u2019s disease and other forms of dementia are top concerns for older people and their families. Americans are living longer and medical costs are climbing, and there are no widely available treatments that have been shown to slow cognitive decline.\nMore than 6 million Americans, most of them age 65 or older, may have dementia caused by Alzheimer\u2019s, according to the National Institute on Aging. The Centers for Disease Control and Prevention expects that number to triple over the next 40 years. Women face a 37% lifetime risk of developing the brain-destroying disease; for men, who typically don\u2019t live as long, the risk is 24%.\nBiogen \n BIIB,\n -0.63%\n and Eisai \n 4523,\n -2.30%\n have another Alzheimer\u2019s drug, Aduhelm, which was brought to market in 2021 under an accelerated approval process, but that therapy has been dogged by efficacy concerns, safety issues and high costs.\nEisai has said it will file for full approval of lecanemab in the U.S. in the first quarter of next year. The Alzheimer\u2019s Association called for accelerated approval of the drug, and the FDA is expected to decide by Jan. 6 whether to grant that approval.\nUnder an accelerated approval, Centers for Medicare and Medicaid Services (CMS) policy would limit access to lecanemab to Medicare beneficiaries who are participating in clinical trials. The Alzheimer\u2019s Association, which has urged changes to the policy to allow coverage of the drug and similar therapies, said the current policy means people wouldn\u2019t be able to access\u00a0\u00a0the treatment within the limited span of time when it might be effective.\nNow read: People who do this one thing every day have half the dementia risk that the rest of us do\nOthers, however, raised questions about whether the drug should be covered by Medicare and Medicaid.\n\u201cCMS already implied they will be quite cautious in covering these types of drugs,\u201d Lyketsos said, adding that he thinks the agency \u201cshould continue to exercise caution.\u201d\nBresdine also raised concerns about the cost of lecanemab. \u201cIt will likely be stratospheric,\u201d he said. \u201cThe money would be far better spent on home and community care for people already with the disease and those providing caregiving.\u201d\nRelated:\u00a0Lilly said its Alzheimer\u2019s drug clears more amyloid plaque than Aduhelm\nOn Thursday, Medicare signaled it was willing to re-evaluate its coverage of Alzheimer\u2019s drugs in light of the latest lecanemab results.\n\u201cI can\u2019t speak to any specifics, but just to say our door is really open,\u201d Chiquita Brooks-LaSure, administrator for CMS, said at the Milken Institute Future of Health Summit, according to media reports. \u201cWe will look at it as new data comes.\u201d\nThe Warren Buffett-led conglomerate requested one or more of its equity holdings be kept confidential.\nJessica Hall is a retirement reporter for MarketWatch.\nJessica Hall is a retirement reporter for MarketWatch.\n\nSource: MarketWatch\n", + "timestamp_ms": 1670601000000, + "published_utc": "2022-12-09T15:50:00Z", + "article_url": "https://www.marketwatch.com/story/new-alzheimers-drug-appears-to-slow-cognitive-decline-but-is-not-a-breakthrough-11670601044", + "label_type": [ + "[1][c] Company-Specific News", + "[2][a] Fundamental Analysis" + ], + 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