File size: 12,339 Bytes
0cac751
 
 
 
 
 
 
 
 
 
 
 
 
21fbe67
0cac751
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
21fbe67
 
 
0cac751
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
 
 
84c8006
 
0cac751
 
d857527
 
 
 
 
 
 
 
 
0cac751
 
 
 
 
 
 
 
 
84c8006
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
0cac751
 
 
 
 
 
 
 
21fbe67
0cac751
 
 
 
21fbe67
84c8006
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
0cac751
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
{
  "type": "document",
  "metadata_information": {
    "title": "The epidemiological impact of an HIV vaccine on the HIV/AIDS epidemic in Southern India",
    "idno": "2160788",
    "producers": [
      {
        "name": "Library",
        "abbr": "ITSKI",
        "affiliation": "World Bank",
        "role": "Curation"
      }
    ],
    "production_date": "2024-05-12",
    "version": "R script, from D&R API, generated on 2024-05-12"
  },
  "document_description": {
    "title_statement": {
      "idno": "2160788",
      "title": "The epidemiological impact of an HIV vaccine on the HIV/AIDS epidemic in Southern India",
      "sub_title": "",
      "alternate_title": "",
      "translated_title": ""
    },
    "authors": [
      {
        "first_name": "",
        "initial": "",
        "last_name": "",
        "affiliation": "",
        "full_name": "Nagelkerke, Nico J.D."
      },
      {
        "first_name": "",
        "initial": "",
        "last_name": "",
        "affiliation": "",
        "full_name": "De Vlas, Sake J."
      }
    ],
    "date_created": "2003-02-28",
    "date_available": "2010-07-01",
    "date_published": "2010-07-01",
    "identifiers": [
      {
        "type": "World Bank D&R",
        "identifier": "2160788"
      },
      {
        "type": "World Bank ID",
        "identifier": "090224b082b059ee"
      },
      {
        "type": "World Bank Chronical ID",
        "identifier": "090224b082b059ee"
      },
      {
        "type": "DOI",
        "identifier": ""
      }
    ],
    "type": "Policy Research Working Paper",
    "abstract": "The potential epidemiological impact of preventive HIV vaccines on the HIV epidemic in Southern India is examined using a mathematical deterministic dynamic compartmental model. Various assumptions about the degree of protection offered by such a vaccine, the extent of immunological response of those vaccinated, and the duration of protection afforded are explored. Alternative targeting strategies for HIV vaccination are simulated and compared with the impact of conventional prevention interventions in high-risk groups and the general population. The impact of disinhibition (increased risk behavior due to the presence of a vaccine) is also considered. Vaccines that convey a high degree of protection in a share of or all of those immunized and that convey life-long immunity are the most effective in curbing the HIV epidemic. Vaccines that convey less than complete protection may also have substantial public health impact, but disinhibition can easily undo their effects and they should be used combined with conventional prevention efforts. Conventional interventions that target commercial sex workers and their clients to increase condom use can also be highly effective and can be implemented immediately, before the arrival of vaccines.",
    "ref_country": [
      {
        "name": "India",
        "code": "IND"
      }
    ],
    "spatial_coverage": "South Asia",
    "languages": [
      {
        "name": "english",
        "code": "en"
      }
    ],
    "volume": "1",
    "number": "WPS2978",
    "url": "http://documents.worldbank.org/curated/en/235371468771598999/pdf/multi0page.pdf",
    "contacts": [
      {
        "name": "Documents and Reports Help Desk",
        "affiliation": "World Bank",
        "email": "documents@worldbank.org",
        "uri": "https://documents.worldbank.org/en/publication/documents-reports/faqs"
      }
    ],
    "usage_terms": "See World Bank Access to Information (https://www.worldbank.org/en/access-to-information)",
    "disclaimer": "The Policy Research Working Paper Series disseminates the findings of work in progress to encourage the exchange of ideas about development issues. An objective of the series is to get the findings out quickly, even if the presentations are less than fully polished. The papers carry the names of the authors and should be cited accordingly. The findings, interpretations, and conclusions expressed in this paper are entirely those of the authors. They do not necessarily represent the views of the International Bank for Reconstruction and Development/World Bank and its affiliated organizations, or those of the Executive Directors of the World Bank or the governments they represent.",
    "security_classification": "Public",
    "keywords": [
      {
        "id": "",
        "name": "men who have sex with men",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "initial value",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "commercial sex worker",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "national aids control",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "rate of condom use",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "sexually transmitted infection",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "hiv vaccine",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "aids vaccine",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "targeting strategies",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "epidemiological impact",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "aids epidemic",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "general population",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "std control",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "public health",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "prevention strategies",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "high-risk group",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "adult population",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "vulnerable group",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "hiv epidemic",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "unsafe sex",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "adult prevalence",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "sexually active",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "mathematical model",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "age structure",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "preventive efforts",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "prevention effort",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "vertical transmission",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "immunization status",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "anonymous reviewer",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "risky sex",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "male circumcision",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "infected adults",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "hiv vaccination",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "syndromic treatment",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "risky behavior",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "preventive intervention",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "candidate vaccine",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "graphical representation",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "hiv prevalence",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "heterosexual transmission",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "medical center",
        "vocabulary": "World Bank",
        "uri": ""
      },
      {
        "id": "",
        "name": "infected individuals",
        "vocabulary": "World Bank",
        "uri": ""
      }
    ],
    "themes": [
      {
        "id": "",
        "name": "",
        "parent_id": "",
        "vocabulary": "",
        "uri": ""
      }
    ],
    "reproducibility": {
      "statement": "",
      "links": [
        {
          "uri": "",
          "description": ""
        }
      ]
    },
    "pricing": "Free",
    "date_modified": "",
    "geographic_units": [
      {
        "name": "",
        "code": "",
        "type": ""
      }
    ],
    "series": "",
    "publisher_address": "",
    "organization": "",
    "topics": [
      {
        "id": "",
        "name": "",
        "parent_id": "",
        "vocabulary": "",
        "uri": ""
      }
    ],
    "relations": [
      {
        "name": "",
        "type": ""
      }
    ],
    "access_restrictions": "",
    "edition": "",
    "notes": [
      {
        "note": ""
      }
    ]
  },
  "provenance": [
    {
      "origin_description": {
        "harvest_date": "2024-05-12",
        "altered": false,
        "base_url": "https://documents.worldbank.org/en/publication/documents-reports/api",
        "identifier": "",
        "date_stamp": "2024-05-12T17:55:28Z",
        "metadata_namespace": "WB_DOCREP"
      }
    }
  ],
  "schematype": "document",
  "tags": [
    {
      "tag": "",
      "tag_group": ""
    }
  ],
  "additional": {
    "additional.wds_action": "",
    "additional.wds_projectid_sort": "",
    "additional.wds_owner": "",
    "additional.project_id": "",
    "additional.project_name": "",
    "additional.wds_lndinstr_exact": "",
    "additional.wds_prdln_exact": "",
    "additional.wds_countrycode": "",
    "additional.wds_bdmdt": "",
    "additional.wds_closedt": "",
    "additional.wds_loannbr": "",
    "additional.wds_trustfund": "",
    "additional.wds_ml_repnme": "",
    "additional.wds_entityids": {
      "entityid": ""
    },
    "additional.wds_historic_topic": "",
    "additional.wds_totvolnb": "",
    "additional.wds_EnvironmentalCategory": "",
    "additional.wds_disclosure_type": "",
    "additional.wds_origin_unit": "",
    "additional.unhcr_report_url": "",
    "additional.unhcr_title": "",
    "additional.unhcr_format": "",
    "additional.unhcr_sources": [
      ""
    ],
    "additional.unhcr_posted": "",
    "additional.unhcr_originally_published": "",
    "additional.unhcr_origin": "",
    "additional.unhcr_primary_country": [
      ""
    ],
    "additional.unhcr_other_countries": [
      ""
    ],
    "additional.unhcr_themes": [
      ""
    ],
    "additional.unhcr_languages": [
      ""
    ],
    "additional.unhcr_disasters": [
      ""
    ],
    "additional.unhcr_disaster_types": [
      ""
    ],
    "additional.unhcr_pdf_url": ""
  }
}