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SARS-CoV-2 set dataset card
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README.md
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Dataset of 104972 antibodies screened for binding the SARS-CoV-2 HR peptide, described in [Engelhart et al. (2022)](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606274/), were obtained from [Zenodo](https://zenodo.org/record/5095284).
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Average predicted logK<sub>D</sub> values were used for classifying sequences as binders and non-binders:
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* logK
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Dataset of 104972 antibodies screened for binding the SARS-CoV-2 HR peptide, described in [Engelhart et al. (2022)](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606274/), were obtained from [Zenodo](https://zenodo.org/record/5095284).
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Average predicted logK<sub>D</sub> values were used for classifying sequences as binders and non-binders:
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* logK<sub>D</sub><3 = binders
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* logK<sub>D</sub>>=4 = non-binders
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* logK<sub>D</sub>>=3 and logK<sub>D</sub> = ambiguous; removed.
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Using these criteria, we have 51590 sequences remaining; these were stratified into an 80:10:10 ratio for training, test, validation, leading to:
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* 41787 sequences in training
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* 5159 sequences in validation
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* 4644 sequences in test
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Example
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| vh | vl | label |
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| ------- | ------- | ----- |
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| EVQ... | DIQ... | 1 |
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| EVQ... | DIQ... | 0 |
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| EVQ... | DIQ... | 0 |
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| EVQ... | DIQ... | 1 |
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References
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* [Engelhart et al. (2022) paper](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606274/)
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* [Zenodo link for dataset](https://zenodo.org/record/5095284)
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