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{"artist": "Bow Wow", "songs": [{"album": "Greenlight 4", "title": "Boy or Girl", "year": "2010-06-01", "lyrics": "[Hook]\nIf I have a girl, I pray she won't be nothing like none of these hoes I have met throughout my life\nTreat her now to be a lady hope she don't act like her mother\nTreat her to be independent, j-j-just me and my daughter now\nIf I have a boy I hope he don't be nothing like me when I was young, thought I knew a lot about life\nTeach him how to be a man, teach him how to be strong\nTell him how to treat a woman j-j-just me and my son\n\n[Verse 1]\nNow I can't lie, daddys feelin kinda nervous\nI make your mother mad at times, I don't do it on purpose\nI'mma be honest just saying. aight, she don't deserve it\nYou wouldn't be on the way so all the time we spent she was worth it\nNow if she is a girl, she gonna be my daddy's little baby\nThey niggas ain't shit, stayin away from them cuz they crazy\nAnd treat you like the queen you are, cause you my angel sent from the heavens above\nGod I can't thank you.. enough\nThought I was gone get fucked but I'm a man gotta stand on my own 2 feet\nDo what I can cause I want the best\nNot just for us, but for our daughter\nJust the thought that I got 1 on the way, makes me go harder\nTreat yourself with respect, carry you self like a lady\nGo to school get your education you can do it and baby I'll be right there rootin\nLike yea that's my girl, I'm your father\nWouldn't trade you for nothing in this world....HEY\n\n[Hook]\n\n[Verse 2]\nIf I have a boy, he probably gonna have my eyes dress em just like me when we hang out, he match my fly\nThen I met every pop on every football game he got\nEvery step of the way I'mma be there\nUnlike my pops. but if he wanna rap and act just like me\nI would tell him you can be anything you wanna be\nTryna give you all the things my father ain't give me\nSee my momma mad cause I I'mma always want you with me\nAnd you know I'mma hold you down, cause you is my little man\nWish me and your mother saw eye to eye so we can could be a fam but I guess that war is done\nI wish I could make it work just me and my son but I can't lie I can't stop loving her... go\n\n[Hook]\n\n[Bridge]\nCan we stop with all the fuss and get back to how we used to to be\nI know you hate my ways but by now you should be used to me\nYea I got to stand up, time for me to man up\nTo all the good dads in the world put ur hands up\n\n[Hook]\nTell him how to treat a woman j-j-just me and my son", "image": "https://images.genius.com/1cf6a2a56aa5cf126f6f980607262d5e.300x300x1.jpg"}]} |
{"poster":"VOY A LO MALDITO","date":"2019-11-27T16:03:55.691+0000","title":"Increíble la diferencia entre regiones","subforum":"Charlas Generales","up_votes":1,"down_votes":8,"body":"Me parece envidiable el carácter que tienen los jugadores de otras regiones frente al cambio de nick, si entran a los foros de NA https://boards.na.leagueoflegends.com/en/ o al foro de EUW https://boards.euw.leagueoflegends.com/es/ todos son hilos alegando y mostrando el descontento en torno a este tema, se general discusión y opiniones frente al mal actuar de Riot, el como no debería haberse ejecutado el cambio etc. Mientras que en este foro de LAS hay players que defienden como Riot pasa a llevar a sus jugadodores, se deja al descubierto la mentalidad latina de dejar que hagan lo que quieran con nosotros y quedarnos callados. Les dejo los links a los foros por si quieren leer las diversas opiniones que existen al respecto. \r\n\r\nSuerte en sus clasificatorias invocadores! {{sticker:slayer-jinx-wink}}","replies":[{"poster":"Mazoku","date":"2019-11-27T16:08:29.158+0000","up_votes":1,"down_votes":1,"body":"> y opiniones frente al mal actuar de Riot\n\nQue mal actuar?","replies":[{"poster":"Aegis","date":"2019-11-27T16:10:49.597+0000","up_votes":1,"down_votes":0,"body":"No solucionar los problemas inmediatamente o dar explicacion (creo que es eso, no?)","replies":[{"poster":"Mazoku","date":"2019-11-27T16:15:37.886+0000","up_votes":1,"down_votes":0,"body":"Yo no tuve ningun problema al cambiar de usuario. Por eso pregunto, que problemas o mal actuar?","replies":[{"poster":"rama144","date":"2019-11-27T16:39:16.655+0000","up_votes":2,"down_votes":0,"body":"Ademas que se aviso con tiempo","replies":[]},{"poster":"Aegis","date":"2019-11-27T17:00:21.991+0000","up_votes":1,"down_votes":0,"body":"yo tampoco tuve problemas de cambiar usuario, total imaginación sobra, y si no te acordas lo anotas en el celu o en un papel a parte hasta que logres recordarlo o como dijo otro en cambiar una minima letra/número al nick, pero viste como siempre quieren todo rapido o no logran entender lo que se esta implementando, a mi parecer esta mejor el cambio que estan haciendo, como dije en otro lado quizás no ahora pero a futuro quiera probar otros juegos de riot y sería mucho más problema tener que recordar varios nick para estar jugando los juego de una misma empresa, sería absurdo","replies":[]}]}]}]},{"poster":"JACKY FANBOY","date":"2019-11-27T16:18:36.480+0000","up_votes":2,"down_votes":0,"body":"Se viene avisando hace tiempo, ademas muchos tienen el mismo nombre de usuario porque creimos que iba a ser solo eso\n\nademas es mucho llorar por un nombre que solo ves tú\n\nDe hecho me alegra, ya que era uno de los que tenia el mismo nombre en ambos lados\nsi hubiera sabido no cambiaba el nombre xD","replies":[]},{"poster":"PancitoConKripi","date":"2019-11-27T16:12:39.457+0000","up_votes":2,"down_votes":0,"body":"No se trata de eso man, pero si ya habían puesto un aviso hace dos semanas más o menos sobre esto, no te parece obvio? Se que a nadie le gusta cambiar su nick por esto, pero cuando aceptas algo, tienes que afrontarlo, comparando un ejemplo al trabajar, se debe leer el contrato y comprenderlo, luego si aceptas o no es decisión tuya, pero si firmas sabiendo que hay una condición que no te gusta, y aún así lo firmas, después no te puedes a poner a reclamar, en el lol m es cuando instalas el juego hay dos opciones acepto y no acepto, es decisión tuya...\nNo es mentalidad latina, es ser consecuente de lo que aceptas (ahora si no te leíste todos los términos del juego, es problema tuyo)\nAhora lo que algunos de mis amigos afectados estan haciendo es cambiar solo un símbolo de su nick, por ejemplo cambiar la o por la ō, si aún así niegas la situación, tu cuenta no se podrá usar para jugar y si es que estos flacos tragamonedas no te la borran, saludos.","replies":[{"poster":"JACKY FANBOY","date":"2019-11-27T16:24:36.125+0000","up_votes":1,"down_votes":0,"body":"de hecho a mi me alegra poder cambiar\ntenia el mismo nombre en ambos lados","replies":[]}]},{"poster":"Shirotani","date":"2019-11-27T16:26:46.004+0000","up_votes":1,"down_votes":0,"body":"Lo que pasa es que los Rioters encargados de los cambios son de NA, si allá se quejan, los van a leer y/o van a tomar medidas.\n\nSi nos quejamos acá, el rioter de acá (siempre y cuándo aparezca alguno) le va a pasar el mensajito al de NA, que acá se están quejando.","replies":[{"poster":"Tenori Taiga","date":"2019-11-27T17:05:46.857+0000","up_votes":2,"down_votes":1,"body":"No papu, los rioter aca contestaron un mensaje, que pasi, le metieron negativos y refutaban los argumentos con un, \"no, eso no es asi porque lo digo yo\".\nHay que sacarse ese chip de que riot esta para jodernos y todo lo que hace nos perjudica","replies":[{"poster":"Shirotani","date":"2019-11-28T00:00:06.485+0000","up_votes":1,"down_votes":0,"body":"> [{quoted}](name=Tenori Taiga,realm=LAS,application-id=v7qsfXsE,discussion-id=NABdY4eH,comment-id=00030000,timestamp=2019-11-27T17:05:46.857+0000)\n>\n> No papu, los rioter aca contestaron un mensaje, que pasi, le metieron negativos y refutaban los argumentos con un, \"no, eso no es asi porque lo digo yo\".\n> Hay que sacarse ese chip de que riot esta para jodernos y todo lo que hace nos perjudica\n\n\n¿Y eso que tiene que ver con lo que puse?","replies":[]}]}]},{"poster":"Carmat","date":"2019-11-27T18:08:20.601+0000","up_votes":1,"down_votes":0,"body":"WTF yo no veo diferencia , en toda las regiones hay gente que no se informa bien del porque de ese actuar y esta que se queja incluido aqui que vi muchos post llorones , y también hay players que se informan y saben muy bien de que se trata. \n\nUn ejemplo de que la gente escribe por escribir sin informarse es el quien creo el titulo de este hilo de post y todavía dice\"frente al cambio de nick\" demostrando que no se informa del porque del cambio , cuando los que sí se informan saben que es cambio de usuario de inicio de sesión.","replies":[]},{"poster":"rokushoger","date":"2019-11-27T17:45:55.267+0000","up_votes":1,"down_votes":0,"body":"Puede ser que tengan más caracter, o que simplemente no es para tanto. Después de todo ese nombre solo lo ves tú, y te va a ayudar a tener uno solo para todo lo que juegues de Riot, así que no veo que tanto drama.","replies":[]},{"poster":"Tenori Taiga","date":"2019-11-27T17:14:36.091+0000","up_votes":1,"down_votes":0,"body":"Comamoa mierda que millones de moscas no se equivocan, no?\nSe aviso con tiempo, se informo por los medios que tiene riot para hacernos llegar información.\nTe estan dando una comodidad que es la unificación de cuentas, que antes no la tenias, y ahora si. Obiamente se cambia el sistema y hay que hacer cambios para adaptarse. Durantw un mes te chupo un huevo tu cuenta, recien ahora te venis a acordar, y te quejas. Mira que importante ea tu cuenta por la que reclamas que durante todo este tiempo no moviste un dedo.\nEl problema no es esa boludes de la mentalidad latina que flasheas, el problema es la mentalidad llorica y ese discurso dogmatico de riot es mala y nos maltrata, hasta el punto que consideramos maltrato algo que nos beneficia","replies":[]}]} |
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{"poster":"US iWhy","date":"2020-01-23T02:44:54.358+0000","title":"Eritra fue baneada por eloboost y ahora trabaja en actualizando?","subforum":"Esports","up_votes":26,"down_votes":2,"body":"¿Alguien me explica comó es posible que una persona que fue baneada por eloboost ahora este trabajando con Riot?\r\n{{sticker:zombie-brand-facepalm}}","replies":[{"poster":"UNKNOWSER","date":"2020-01-23T05:11:50.542+0000","up_votes":0,"down_votes":20,"body":"Eso fue hace 50 años, no vivas en el pasado crack","replies":[{"poster":"US iWhy","date":"2020-01-23T06:26:04.907+0000","up_votes":20,"down_votes":0,"body":"> [{quoted}](name=UNKNOWSER,realm=LAS,application-id=Ky2nrTjR,discussion-id=LPpAZUXR,comment-id=0006,timestamp=2020-01-23T05:11:50.542+0000)\n>\n> Eso fue hace 50 años, no vivas en el pasado crack\n\nEn ese caso que desbaneen a Dopa XDDD","replies":[]}]},{"poster":"PasoPackXHonores","date":"2020-01-23T04:07:53.624+0000","up_votes":17,"down_votes":1,"body":"A rito no le importa. Coscu era alto flamer y lo contrataron para eventos. Y otra que no voy a nombrar que estuvo en la pagina principal, 2 veces y es tremenda flamer.","replies":[{"poster":"Mikeel Cornish","date":"2020-01-23T04:20:08.022+0000","up_votes":2,"down_votes":1,"body":"> Y otra que no voy a nombrar que estuvo en la pagina principal, 2 veces y es tremenda flamer.\n\nHablas de Suga?","replies":[{"poster":"Majora","date":"2020-01-23T07:11:59.718+0000","up_votes":15,"down_votes":1,"body":"Que repugnante que es esa tipa\n.","replies":[{"poster":"Rendirsé Jamás","date":"2020-01-23T13:43:46.034+0000","up_votes":1,"down_votes":0,"body":"A todos nos cae mal parece jajaja.","replies":[]}]}]},{"poster":"Yamisuke","date":"2020-01-24T06:09:02.618+0000","up_votes":1,"down_votes":0,"body":"Ya me la veo venir el año que viene en el actualizando. Toco madera {{summoner:3}}","replies":[]},{"poster":"Pandora Journey","date":"2020-01-23T13:46:10.907+0000","up_votes":1,"down_votes":0,"body":"> [{quoted}](name=PasoPackXHonores,realm=LAS,application-id=Ky2nrTjR,discussion-id=LPpAZUXR,comment-id=0004,timestamp=2020-01-23T04:07:53.624+0000)\n>\n> A rito no le importa. Coscu era alto flamer y lo contrataron para eventos. Y otra que no voy a nombrar que estuvo en la pagina principal, 2 veces y es tremenda flamer.\n\nLa intriga... la curiosidad me mata bro","replies":[]},{"poster":"whiv0q","date":"2020-01-23T11:11:06.912+0000","up_votes":1,"down_votes":0,"body":"a coscu ni lo quieren los de riot las que decis xD","replies":[{"poster":"Endrance","date":"2020-01-24T00:16:05.639+0000","up_votes":1,"down_votes":1,"body":"> [{quoted}](name=whiv0q,realm=LAS,application-id=Ky2nrTjR,discussion-id=LPpAZUXR,comment-id=00040001,timestamp=2020-01-23T11:11:06.912+0000)\n>\n> a coscu ni lo quieren los de riot las que decis xD\n\nCoscu no se quiere ni el mismo.... lo unico bueno de coscu son los bans que se comio.\nGran parte de la toxicidad de este servidor es por culpa de su \"influencia\".","replies":[]}]}]},{"poster":"The Fall of Troy","date":"2020-01-23T05:20:10.971+0000","up_votes":4,"down_votes":2,"body":"La contrataron por ser una carita bonita mas","replies":[{"poster":"NSG OneShoot","date":"2020-01-23T07:44:14.896+0000","up_votes":16,"down_votes":1,"body":"es mas fea que estornudo con diarrea","replies":[]},{"poster":"Nikoratzu","date":"2020-01-23T16:54:51.840+0000","up_votes":4,"down_votes":0,"body":"Carita bonita? aun con todo el maquillaje es terrible fea, si fuera por eso hubiesen dejado a Pancha.","replies":[]}]},{"poster":"Skgwet","date":"2020-01-23T13:45:12.155+0000","up_votes":8,"down_votes":0,"body":"alguien se lo dijo por twitter y ella se enojo y lo bloqueo XD","replies":[]},{"poster":"HeinmiinkSmurf","date":"2020-01-23T03:04:22.654+0000","up_votes":7,"down_votes":0,"body":"vivimos en una sociedad hermano, nada más xD","replies":[]},{"poster":"Mikeel Cornish","date":"2020-01-23T03:00:44.234+0000","up_votes":8,"down_votes":1,"body":"De hecho fue baneada 2 veces antes de permaban...","replies":[{"poster":"US iWhy","date":"2020-01-23T03:23:56.817+0000","up_votes":1,"down_votes":0,"body":"> [{quoted}](name=Mikeel Cornish,realm=LAS,application-id=Ky2nrTjR,discussion-id=LPpAZUXR,comment-id=0000,timestamp=2020-01-23T03:00:44.234+0000)\n>\n> De hecho fue baneada 2 veces antes del permaban...\n\nLMAO, Riot in a nutshell xDDD","replies":[]}]},{"poster":"LeyendaRankeQ","date":"2020-01-23T07:41:51.547+0000","up_votes":6,"down_votes":0,"body":"Tyler no era pedazo de Flamer y ahora es la cara de los eventos principales de Riot? \nEs asi podes ser flamer y romper las reglas pero si le generas dinero a Riot sos bienvenido.","replies":[{"poster":"rokushoger","date":"2020-01-24T12:41:24.585+0000","up_votes":2,"down_votes":0,"body":"> Tyler no era pedazo de Flamer y ahora es la cara de los eventos principales de Riot?\n\nEs un asco eso. Tal cual.","replies":[]},{"poster":"Cosmic Owl","date":"2020-01-24T02:43:39.639+0000","up_votes":2,"down_votes":0,"body":"acabas de descubrir el marketing bro","replies":[]}]},{"poster":"rokushoger","date":"2020-01-24T12:44:22.884+0000","up_votes":4,"down_votes":0,"body":"A ver si te hago acuerdo de algunas cosas:\n\n1- Desbanearon a uno de los poquísimos casos que ya no era solo permaban sino ban de IP que es Tyler1 y ahora es cara principal de muchos de los eventos de Riot.\n2- El perdonazo de la season de hace 2 años a flamers.\n3- Las invitaciones a eventos de Coscu.\n\nY te extraña esto? A mi me extraña que no agarren a uno de estos permaban que vienen a quejarse al foro y los pongan a castear.","replies":[]},{"poster":"Riot Mokarran","date":"2020-01-23T17:46:04.338+0000","up_votes":9,"down_votes":29,"body":"Hey iWhy.\n\nEs cierto que hace casi 5 años (2015) Eritra tuvo una penalización en su cuenta. No hablamos específicamente de razones de castigo sin embargo si, al momento se cerro todo contacto con ella, pues nos tomamos este tipo de cosas en serio.\n\nSin embargo, ella volvió al ecosistema de streaming y desde entonces ha mantenido un comportamiento acorde al código del invocador. Esto gano nuestra confianza de nuevo y poco a poco comenzamos a invitarla a eventos. De su buen trabajo gano su entrada al LPP en LATAM, lo cual la puso bajo aun mayor rigor de revisión de cuentas y ha seguido manteniendo el mismo estándar. Esto eventualmente la llevo a ser una buena opción para ser backup de Epsy en el Actualizando, y quedamos tan contentos con su participación, que cuando Epsy encontró su nuevo camino, Eritra estuvo entre los posibles hosts y termino siendo nuestra elección. \n\nA nivel compañía creemos en la posibilidad de reformarse, como lo han visto en casos como el de Tyler1. Estamos felices de hacer este tipo de cosas y siempre que vemos a alguien cambiar y aportar al ecosistema nos pone de buenas.","replies":[{"poster":"Migas De Pan","date":"2020-01-23T22:11:09.592+0000","up_votes":13,"down_votes":0,"body":"no veo que se tomen el tema de penalizacion en serio, ya que la comunidad sigue siendo igual de toxica e incluso peor cada vez. Dejen de mentir, anda a saber que hubo de por medio, quizás no, y fue solo por voluntad de su corazon perdonarla, pero QSY, el juego anda cada vez peor y a ustedes les pagan AL PEDO.","replies":[{"poster":"AFK M YI","date":"2020-01-24T18:57:15.877+0000","up_votes":1,"down_votes":0,"body":"Bro, este post es lomás tóxico que hay. Fijate, todas las personas que comentan tiran toxidad. Incluso cuando se quejan de ella estan alimentando una toxicidad extrema.\nEsto de apuntar con el dedo es igual de toxico que flammear. \nY estoy cansado de ver gente que se queja del juego y de riot y siguen jugando todos los dias. Aca hay demasiados pibes que quieren atencion.","replies":[{"poster":"Migas De Pan","date":"2020-01-25T02:11:31.684+0000","up_votes":1,"down_votes":0,"body":"Yo creo que tienen algo de razón, el juego anda como el ORTO, y riot no hace nada, NADA. En este caso el que inicio el post solo estaba preguntando, solo que eso dio lugar a mas comentarios de \"toxicidad\", el post quizás no tenia esa intensión. Ademas de si es un tema PUBLICO, tienen derecho a opinar, justamente es PUBLICO.","replies":[{"poster":"AFK M YI","date":"2020-01-25T18:09:06.991+0000","up_votes":1,"down_votes":0,"body":"Bro, el juego no anda mal. El juego anda bien. Lo que anda mal son las pc de hace 40 años que tienen. El cliente si es una mierda, pero el juego en si, anda bien.\nY yo te lo digo que no tengo una pc para jugar lo que sea, me corre el lol en 120 fps, todo bajo. Y aun asi mi pc es vieja, dentro de dos años ya no me sirve mas.","replies":[{"poster":"Migas De Pan","date":"2020-01-28T14:42:04.987+0000","up_votes":3,"down_votes":0,"body":"No bro, estas mal, pero que queres que te diga? anda mal y punto, no tengo mala pc me anda en alto con buenos fps, pero el problema son los bugs solo que no te informas, así imposible discutir.","replies":[]}]}]}]}]},{"poster":"Endrance","date":"2020-01-24T00:12:59.682+0000","up_votes":3,"down_votes":0,"body":"> [{quoted}](name=Riot Mokarran,realm=LAS,application-id=Ky2nrTjR,discussion-id=LPpAZUXR,comment-id=000f,timestamp=2020-01-23T17:46:04.338+0000)\n>\n> Hey iWhy.\n> \n> Es cierto que hace casi 5 años (2015) Eritra tuvo una penalización en su cuenta. No hablamos específicamente de razones de castigo sin embargo si, al momento se cerro todo contacto con ella, pues nos tomamos este tipo de cosas en serio.\n> \n> Sin embargo, ella volvió al ecosistema de streaming y desde entonces ha mantenido un comportamiento acorde al código del invocador. Esto gano nuestra confianza de nuevo y poco a poco comenzamos a invitarla a eventos. De su buen trabajo gano su entrada al LPP en LATAM, lo cual la puso bajo aun mayor rigor de revisión de cuentas y ha seguido manteniendo el mismo estándar. Esto eventualmente la llevo a ser una buena opción para ser backup de Epsy en el Actualizando, y quedamos tan contentos con su participación, que cuando Epsy encontró su nuevo camino, Eritra estuvo entre los posibles hosts y termino siendo nuestra elección. \n> \n> A nivel compañía creemos en la posibilidad de reformarse, como lo han visto en casos como el de Tyler1. Estamos felices de hacer este tipo de cosas y siempre que vemos a alguien cambiar y aportar al ecosistema nos pone de buenas.\n\nA todo esto... ¿solo mujeres en actualizando? por que van pasando como 4 presentadoras y no veo que se tome en cuenta a ningún hombre ¿buscan presentadora o posible pareja?\n\nNo se, como medida me parece \"meter la pata\" , como imagen, PÉSIMA.\nNo se ve a alguien que se reformo y le dieron la oportunidad... se ve como a alguien que infringió las reglas y la premiaron por eso.\n\nMala decisión.","replies":[{"poster":"legalícenla","date":"2020-01-26T02:06:11.754+0000","up_votes":1,"down_votes":1,"body":"> [{quoted}](name=Endrance,realm=LAS,application-id=Ky2nrTjR,discussion-id=LPpAZUXR,comment-id=000f0004,timestamp=2020-01-24T00:12:59.682+0000)\n>\n> A todo esto... ¿solo mujeres en actualizando? por que van pasando como 4 presentadoras y no veo que se tome en cuenta a ningún hombre ¿buscan presentadora o posible pareja?\n> \n> No se, como medida me parece \"meter la pata\" , como imagen, PÉSIMA.\n> No se ve a alguien que se reformo y le dieron la oportunidad... se ve como a alguien que infringió las reglas y la premiaron por eso.\n> \n> Mala decisión.\n\nMan, fue HACE 5 AÑOS, existe la posibilidad de redimirse y demostrar arrepentimiento en menos de 1 año, y no lo va a poder hacer en 5? Esto es prueba del perdón de riot, un jugador la caga y luego lo enmienda\n\nAparte, tiene sentido que sólo hayan mujeres en actualizando, literal es de los pocos lugares que tienen las mujeres en el LoL, cuál hay que sean mujeres?? no entiendo","replies":[{"poster":"Endrance","date":"2020-01-26T02:23:49.840+0000","up_votes":2,"down_votes":0,"body":"> [{quoted}](name=legalícenla,realm=LAS,application-id=Ky2nrTjR,discussion-id=LPpAZUXR,comment-id=000f00040000,timestamp=2020-01-26T02:06:11.754+0000)\n>\n> Man, fue HACE 5 AÑOS, existe la posibilidad de redimirse y demostrar arrepentimiento en menos de 1 año, y no lo va a poder hacer en 5? Esto es prueba del perdón de riot, un jugador la caga y luego lo enmienda\n> \n> Aparte, tiene sentido que sólo hayan mujeres en actualizando, literal es de los pocos lugares que tienen las mujeres en el LoL, cuál hay que sean mujeres?? no entiendo\n\n¿Sabes cual hay que solo sean mujeres? que si solo fueran hombres y siempre hombres, saltarian a pedir mujeres y habria que bancarsela, por que ahora al parecer vivimos en una sociedad en donde aparentemente ser hombre es malo.\nEntonces me molesta ver solo mujeres en el mismo lugar.. llamame machista si queres me da lo mismo.\nPero me aburri de ser politicamente correcto como todos, si tengo que ser honestos, ella esta ahí por que \"le queda lindo el escote\" pero la verdad tiene menos gracia que ver crecer el pasto.\n\nPor que el carisma de ella ¿donde lo dejo? ¿ o el ponerle onda viene con algun DLC?\n\nMedia pila.","replies":[]}]}]},{"poster":"Yoen","date":"2020-01-23T18:06:52.460+0000","up_votes":9,"down_votes":3,"body":"Si es así, ojalá quieran darle una oportunidad a Dopa.\n\nSaludos y buen día, hace tiempo ^^\nque no veo rioters acá en el foro :(","replies":[{"poster":"MILFortune","date":"2020-01-24T01:14:45.238+0000","up_votes":2,"down_votes":0,"body":"> [{quoted}](name=Yoen,realm=LAS,application-id=Ky2nrTjR,discussion-id=LPpAZUXR,comment-id=000f0000,timestamp=2020-01-23T18:06:52.460+0000)\n>\n> Si es así, ojalá quieran darle una oportunidad a Dopa.\n> \n> Saludos y buen día, hace tiempo ^^\n> que no veo rioters acá en el foro :(\n\nYa tenemos el caso mundial del coronavirus, para qué querés más plaga ?","replies":[]},{"poster":"GtiMK4","date":"2020-01-23T20:00:14.896+0000","up_votes":2,"down_votes":1,"body":"Una cuenta lv 30, estamos salvados","replies":[]}]},{"poster":"US iWhy","date":"2020-01-23T18:23:39.588+0000","up_votes":10,"down_votes":1,"body":"> [{quoted}](name=Riot Mokarran,realm=LAS,application-id=Ky2nrTjR,discussion-id=LPpAZUXR,comment-id=000f,timestamp=2020-01-23T17:46:04.338+0000)\n>\n> Hey iWhy.\n> \n> Es cierto que hace casi 5 años (2015) Eritra tuvo una penalización. No hablamos específicamente de razones de castigo sin embargo si, esa cuenta se perdió y al momento se cerro todo contacto con ella, pues nos tomamos este tipo de cosas en serio.\n> \n> Sin embargo, ella volvió al ecosistema de streaming y desde entonces ha mantenido un comportamiento acorde al código del invocador. Esto gano nuestra confianza de nuevo y poco a poco comenzamos a invitarla a eventos. De su buen trabajo gano su entrada al LPP en LATAM, lo cual la puso bajo aun mayor rigor de revisión de cuentas y ha seguido manteniendo el mismo estándar. Esto eventualmente la llevo a ser una buena opción para ser backup de Epsy en el Actualizando, y quedamos tan contentos con su participación, que cuando Epsy encontró su nuevo camino, Eritra estuvo entre los posibles hosts y termino siendo nuestra elección. \n> \n> A nivel compañía creemos en la posibilidad de reformarse, como lo han visto en casos como el de Tyler1. Estamos felices de hacer este tipo de cosas y siempre que vemos a alguien cambiar y aportar al ecosistema nos pone de buenas.\n\nQué sigue? Qué no baneen a Adrelina Esperanza por eloboost y le den LPP? ... Ah no para, no lo han baneado xD","replies":[{"poster":"Migas De Pan","date":"2020-01-25T02:14:52.020+0000","up_votes":1,"down_votes":0,"body":"Si POR FAVOR hagan algo con ese chabon, o bueno mas bien que hagan algo con los compañeros, que se benefician del eloboost cuando deberían estar en plata bajo, literalmente están en diamante alto gracias a 1 persona, y ni siquiera llegan a aprender algo del juego, solo son marionetas que repiten lo mismo en cada partida haciendo que funciones con las habilidades de Adrelina.\nPero a RIOT LE CHUPA BUEN UN HUEVO. Después dicen que no nos quejemos.","replies":[]}]},{"poster":"1997TDA","date":"2020-01-23T18:37:17.745+0000","up_votes":7,"down_votes":0,"body":"Me parece medio hipócrita igual, a mi me permabanearon la cuenta por insinuar que para subir de hierro a diamante tenés que tener un duo o pagarle a alguien para que lo sea, lo cual tomaron como si ofreciera eloboost. Lo peor de todo el tema es que esa cuenta es rank 1 con Shen y no puedo subir nada a los foros por el baneo sin sentido que me metieron.","replies":[{"poster":"Ð r o ł e","date":"2020-01-24T01:54:17.926+0000","up_votes":1,"down_votes":0,"body":"Igual, nadie sube de hierro a diamante. Menos en una sola season. Se hace un seguimiento a la cuenta, un patron, si tu promedio de nivel de juego fue de 0 a 100 misteriosamente de la nada, obviamente te estan eloboosteando.","replies":[{"poster":"rokushoger","date":"2020-01-24T12:39:31.378+0000","up_votes":1,"down_votes":0,"body":"Eso es relativo. Hay gente como yo que hace muchos años que jugamos (de hecho juego desde antes de S1) y muchos de ellos (yo no, pero conozco un par de casos) es probable que tengan habilidad suficiente para hacerlo. El tema es que si nunca han ranqueado tal vez caigan entre hierro y plata de inicio y por tanto si que pudiera darse el caso. Son poquísimos pero puede suceder.","replies":[]}]}]}]},{"poster":"Yamisuke","date":"2020-01-24T06:08:22.560+0000","up_votes":3,"down_votes":0,"body":"Y yo acá subiendo como todos los demás cuando puedo pagar eloboost, total después de un tiempo si pongo carita tierna y no lo hago mas Riot me perdona, y es más, me contrata. \n\n{{sticker:slayer-jinx-wink}}","replies":[]},{"poster":"IITheKingII","date":"2020-01-23T15:43:18.116+0000","up_votes":3,"down_votes":0,"body":"Riot Latam , no lo entenderias .","replies":[]},{"poster":"Nikoratzu","date":"2020-01-23T03:42:52.503+0000","up_votes":2,"down_votes":0,"body":"Creo que cobra barato y riot latam ya no tiene presupuesto :/","replies":[{"poster":"US iWhy","date":"2020-01-23T06:29:21.539+0000","up_votes":3,"down_votes":0,"body":"> [{quoted}](name=Nikoratzu,realm=LAS,application-id=Ky2nrTjR,discussion-id=LPpAZUXR,comment-id=0002,timestamp=2020-01-23T03:42:52.503+0000)\n>\n> Creo que cobra barato y riot latam ya no tiene presupuesto :/\n\nSe nota el bajo presupuesto desde que sacaron a Nosfeh y Skyshock. Sin mencionar que Farenheit sigue como caster XD.","replies":[]}]},{"poster":"Ebrio De Lag","date":"2020-01-23T05:17:46.168+0000","up_votes":3,"down_votes":0,"body":"Respuesta: si.","replies":[]},{"poster":"ASUS Felipe","date":"2020-01-23T03:46:44.233+0000","up_votes":2,"down_votes":1,"body":"si supieras que hasta los mismos de riot son eloboosteados o tienen gente para que le suba cuentas jeje","replies":[]},{"poster":"JoniiCasanova","date":"2020-01-26T01:19:54.159+0000","up_votes":1,"down_votes":0,"body":"DALE LOS RIOTER LE DAN MAS BOLA AL PUTERIO QUE LAS NECESIDADES REALES COMO EL SOPORTE A JUGADORES.- {{sticker:slayer-jinx-unamused}}","replies":[]},{"poster":"Ordane","date":"2020-01-25T00:15:21.071+0000","up_votes":1,"down_votes":0,"body":"Y a mi ni me quieren explicar que puto programa de tercero es el porque me banearon, sigo pensando si el de runas o el de para ver elo dentro del game?¿","replies":[]},{"poster":"Vöhi","date":"2020-01-24T05:27:38.715+0000","up_votes":1,"down_votes":0,"body":"YYYY a Riot cuando le an interesado sus jugadores siempre nos pasan por encima mientras les hagan ganar dinero puedes ser el trolsito mas grande del lol pero si les estas haciendo ganar arto dinero de alguna manera no te haran nada {{sticker:zombie-brand-clap}}","replies":[]},{"poster":"I Love Michis","date":"2020-01-23T20:10:51.644+0000","up_votes":1,"down_votes":0,"body":"Tyler1 se volvio un showman siendo un flamer hecho y derecho; termino siendo su personaje.","replies":[]},{"poster":"Rendirsé Jamás","date":"2020-01-23T13:48:20.694+0000","up_votes":2,"down_votes":2,"body":"***","replies":[{"poster":"Nikoratzu","date":"2020-01-23T17:25:05.498+0000","up_votes":1,"down_votes":0,"body":"No creo que sea tan así, los streamers mas populares del lol son en mayoría hombres y para que la gente te vea lo mas importante es ser carismático no bueno jugando.\nObvio que enseñar escote también atrae pero si es aburrida no va a retener audiencia. ","replies":[]}]}]} |
{"title": "Three killed in accident at Divulapitiya", "content": ["Three persons killed and one injured following a collision between a lorry and a cab at Divulapitiya, Police said\u2026. "], "link": "https://www.onlanka.com/news/three-killed-in-accident-at-divulapitiya.html", "date_published": "July 12, 2012", "category": "Local News"} |
{"poster":"Captain Macmar","date":"2015-03-11T17:00:14.166+0000","title":"Top Laner sucht Team","subforum":"Clans & Teams","up_votes":3,"down_votes":3,"body":"Hallo,\r\n\r\nich suche ein Team, das noch keinen Top Laner hat. Ich bin zwar erst Bronze V aber min. auf dem niveau von Silber II, jeder der schon mal Bronze V war weiss wie schwer es ist raus zu kommen, weil man entweder mit Trollern, AFK´lern etc. zu tu hat. Ich suche einfach ein schönes Team mit netten Membern.\r\n\r\nBei Interesse bitte anschreiben\r\n\r\nFreundliche Grüße MacmarHD","replies":[]} |
{"poster":"ReFLeXPG0123","date":"2015-08-15T08:21:45.769+0000","title":"Megérte-e megvennem ?","subforum":"Tippek és trükkök","up_votes":1,"down_votes":2,"body":"Tegnap éjfélkor vettem meg, és ma reggel próbáltam ki nagyon tettszik a karakter meg minden csak így profibb lolosoktól hogy megért-e megvennem választ előre is köszönöm! :) Buildem: {{summoner:4}} {{summoner:14}} {{item:3087}} {{item:3031}} {{item:3006}} {{item:3072}} {{item:3074}} {{item:3026}}{{champion:157}} ","replies":[{"poster":"ReFLeXPG0123","date":"2015-08-15T18:41:28.573+0000","up_votes":2,"down_votes":0,"body":"KÖSZÖNÖM SZÉPEN MINDENKINEK AKI VÁLASZOLT! :) \nSOKAT SEGÍTETTEK ÖRÖK HÁLA! :D\nEZÉRT NEMSOKÁ KAPTOK EGY VIDEÓT! :O\nAMIT ÉN CSINÁLOK!","replies":[]},{"poster":"M4dr4c","date":"2015-08-15T08:31:57.011+0000","up_votes":2,"down_votes":0,"body":"Ha élvezed vele a játékot akkor megérte. Szerintem ez az egy fontos szempont van csak.","replies":[]},{"poster":"Lord1289","date":"2015-08-15T09:24:13.070+0000","up_votes":1,"down_votes":0,"body":"Szerintem felesleges Yasuo-nak hidra és BT is. Hidra helyett vehetnél egy lastwhispert (legalábbis én azt szoktam). Guardian Angel helyett meg néha jobb egy TrinityForce.","replies":[{"poster":"ReFLeXPG0123","date":"2015-08-15T10:33:46.330+0000","up_votes":1,"down_votes":0,"body":"Én azért nem veszek neki {{item:3142}} -t mert felesleges tárgy\nHallottam arról hogy {{champion:157}} -nak megéri külön rúnát csinálni és belerakni 5 crit-et mert akkor azt megduplázza és megvan a 100%\nMilyen rúnákat vegyek neki?","replies":[{"poster":"Lord1289","date":"2015-08-15T10:57:43.912+0000","up_votes":1,"down_votes":0,"body":"Én a youmuu's-t meg sem említettem de igazából az sem felesleges neki. Van hogy az is jó. Minden ellenség ellen más build kell/kellene. Van hogy yasounak kell venned egy Randuint akár early game-ben. De majd ráérzel hogy ki ellen mit veszel. Próbálgass minél több féle buildet és döntsd el melyik a legjobb a te stílusodhoz.\nÉs például ebből a videóból lemásolhatod a rúnákat, mesterségeket (első pár másodpercben mutatja) : https://www.youtube.com/watch?v=Aq1VHYAXovY","replies":[{"poster":"ReFLeXPG0123","date":"2015-08-15T18:40:27.055+0000","up_votes":1,"down_votes":0,"body":"Köszönöm Szépen! A Rúnákkal rendben vagyok masteries meg 21/9-es! A Mostani buildem:\nEgyéniben próbáltam ki és Solo baronoztam lvl 17-en!\nSorban írom le mit szoktam venni!\nBuild: {{summoner:4}} {{summoner:14}} {{item:3087}} {{item:3031}} {{item:1304}} {{item:3035}} {{item:3072}} {{item:3078}}","replies":[]}]},{"poster":"Tornyi1899","date":"2015-08-15T16:04:38.718+0000","up_votes":1,"down_votes":0,"body":"Az még akkor volt mikor az infinity 25% crit-tel rendelkezett. Most már nem éri meg neki berakni 5%-ot mivel 90 jön csak ki.","replies":[]}]},{"poster":"Invisible Dye","date":"2015-08-15T09:53:14.015+0000","up_votes":1,"down_votes":0,"body":"nem játszok vele, csak kérdezem, hogy a {{item:3142}} nem jobb neki a crit miatt? bár tény, hogy a lw több armorp.-t ad, esetleg helyzetfüggő?","replies":[{"poster":"Lord1289","date":"2015-08-15T11:05:08.790+0000","up_votes":1,"down_votes":0,"body":"Statikk után jobb lehet mint az LW de akkor még megéri inkább egy infinity-t/Bt-t venni neki. És a Statikk+infinity után (szerintem) bőven elég az a 80% crit és az lw olyankor szerintem jobb. De ez az én véleményem mindenki ugy építse ahogy akarja.","replies":[]}]}]},{"poster":"Brăd","date":"2015-08-15T08:22:59.883+0000","up_votes":1,"down_votes":0,"body":"Őőőőő... Mégis mit?","replies":[{"poster":"ReFLeXPG0123","date":"2015-08-15T08:26:14.525+0000","up_votes":1,"down_votes":0,"body":"Bocs, Javítom Kimaradt!","replies":[]}]}]} |
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{"poster":"HΣLIΘS","date":"2015-08-16T11:59:03.995+0000","title":"Néhány BUG amit észrevettem","subforum":"Hibabejelentés","up_votes":5,"down_votes":2,"body":"Sziasztok. Nemrég feltettem 1 kérdést a Támogatás menüben, de lassan 1 hete nincs visszajelzés, így félek ha bugokat jelentenék, arra sem figyelnének fel különösebben. Ezért gondoltam ide írom le ami csak eszembe jut, talán itt hamarabb észreveszik.\nKezdeném azzal, hogy az 1 es szintű Jel típusú Rúnákban van egy hibásan feltüntetett Rúna, mégpedig a Páncéltöréses, ugyanis % ban írja a mennyiséget, holott egységben kellene:\nhttp://kepkezelo.com/images/t8br17w32jv6vhuit36n.jpg\nCsak a boltban hibás, ha megvásároljuk, használjuk, szóval mindenhol máshol, még játékban is normálisan jelzi, azaz egységként tünteti fel.\nA másik az, néha, igaz ritkán, de észrevenni azt, hogy ha egy közepesen távoli helyre kattintunk a Minitérképen, akármelyik hőssel, és a Basic en állunk, akkor megesik hogy beleakad egy Turet be a hős.\nAzt is észrevettem, hogy néha bebugol a felső területen lévő MID es 2 ik Turet (tőlünk számítva), el is magyarázom:\nhttp://kepkezelo.com/images/gj7dgtavdbno82okzaz.jpg\nHa a Turet minket fókuszál, bármelyik hőssel is vagyunk, és a képen feltüntetett piros vonal felett vagyunk, illetve a pirossal besatírozott terület bármely részéről indulva a sárga nyíl irányában menekülünk ki a Turet alól, akkor kiérve, még gyorsan dob mégegy lézernyalábot. Szóval kb 2x olyan gyorsan sebez, még ha épphogy csak elért minket az utolsó hit, és kiérünk a hatótávból, még lead nagyon gyorsan egy hit et. Ez nem mindig áll fent, és csak akkor vettem észre, mikor az előtte lévő (alsó területtől nézve az első) ellenséges Turet már le van rombolva, de még ekkor sem mindig, csak néha.\nHa egy 1 es szintű Rúnát megvásárolunk, és kipipáljuk a Boltban a Hiányzó menüpontot, akkor is feltünteti azt a típusú Rúnát, amit már megvettünk. Több regen is teszteltem.\nHa az Ajándékozás menüben kipipáljuk az Akciós menüpontot, akkor azt írja, Nincs Találat, miközben 3 naponta ugyebár minimum 6 db cucc le van árazva (3 Champ, 3 Skin).\nNéha mikor egy csapat összeállítás kellős közepén vagyunk, a rendszer automatikusan felhozza az adott hőshöz tartozó spelleket, gondolom tudjátok miről van szó (egymás mellett mind, és alatta a leírás röviden), nos ez nem tűnik el, semmiféle kép sem, ezáltal megakadályozza a Chat hez való hozzáférést.\nMég mindig fennáll az a bug, mi alapján mikor elfogadjuk egy meccskereséses játékhoz való csatlakozást, befagy a kliens, és köröz az egér homokórája, de nem történik semmi, mindaddig amíg maga a játék nem indul el. Ezt csak ARAM on vettem észre, de elég idegtépő mikor nem tudunk Rúnákat, Masteries t, Spelleket kiválasztani az adott hőshöz, sőt ezáltal hőst sem tudunk váltani. Ebből eredően akár nagy eséllyel el is bukhatjuk a meccset...\nA \"Nap első győzelme\" jelző sokszor hibásan jelzi az időpontot, mert azt írja egy adott meccs után, hogy már elérhető, aztán a győzelem után nem adja meg az IP t ugye, mert nem jól írta, és akkor már helyesen írja a hátralévő időt.\nNéha befagy a játék egy apró net ingadozás miatt, mikor 130 ról felugrik kb 200 ra a Ping, de ezt követően nem ugrik vissza, hanem felmegy 500 ra, és akár a játék végéig is úgy marad, ekkor jön a Leaver Buster (átok rá, már bocs). A net viszont azonnal visszaáll, ezt leteszteltem játék közben Speedtest.net el, és Youtube val, stb, működött, csupán a kliensben volt 500 as Ping em, és hiába a kliens reset, PC reset, nem ért semmit. GG WP...\nHa Garen el törjük a Nexus t, nagyon közel kell állni hozzá, különben nem fogja ütni. Ez nálam mindig így van, nem tudom mért. Ha távolról kattintok a Nexus ra, odaér, de ha nem kerül elég közel, nem kezdi el ütni, hanem megáll. Ha betolom a Q t, arra sem reagál, és csak lejár az ideje, tehát a 4 sarkát nem nagyon tudom ütni, a 4 oldalát kell fókuszálnom, és azt is úgy hogy minél közelebb kattintsak a Nexus mellé, és úgy kell elkezdeni ütni.\nhttp://kepkezelo.com/images/wja6zcw6xvcx00r2bf2b.jpg\nHa mégvalami eszembe jut, leírom :3 Nektek mi a tapasztalatotok, nálatok ilyesmi nem fordul elő?\nMellesleg nem kell olyan javaslat hogy csináld ezt vagy azt, már mindent próbáltam, kliens reinstall ig kb mindent, de semmi nem segített. Win10 em van, de fennáll az összes probléma 8 és 8.1 alatt is (nemrég tettem fel a 10 et), öcsémnek van jelenleg is Win7, nála is jelentkeznek ilyen problémák (netre nem fogható, hisz általában 90 től 130 ig van jó netem, és e felett pedig nem szoktam játszani, fölösleges...).\nSzerintetek miért nem foglalkoznak a bugokkal, miért mindig csak frissítés, újabb cuccok, stb?\nMellesleg mi a véleményetek arról, hogy míg a saját csapatod Rangját látod a Keretből (bár az sem pontos, nem tudhatod előző szezonokban mit ért el, csak ha lolking en vagy lolnexus on meglesed), viszont az enemy ét sohasem látod? \nNektek nem idegesítő hogy nem tudjátok ki ellen játszotok?\nArról nem beszélve, kivel dob össze, saját, vagy ellenséges csapatban...\nMert amikor elkezdtem ARAM ozni, elsőtől kb 11 meccsig volt 10 WIN em, szériában... Aztán, mintha pikkelne rám a Riot, elkezdett olyan rankedes emberekkel összedobni, azaz ellenségként, hogy volt mikor 20 Def volt kb szériában... Hol én, hol az egész csapatom volt Poor, és nem tudtam mit tenni. Megesett hogy enemy ben Master Challenger volt, Ezreal is volt már enemy ből Challenger, Diamondosok, egy halom Gold os, stb. Az enyémben meg kb hiába volt Platos is, annyit tudott hogy 2/13 ban röhögött rajtunk és b@szott segíteni, koldus az ilyen esküszöm. Namost arra akarok kilyukadni, ha én Unranked es vagyok, mivel érdemlem ki azt hogy Rankedesekkel dob össze, pláne most milyen felállás az mikor meglesem a lolnexus t (tudom néha hibás, de a meccs végén elmondták ki milyen DIV ben van), és azt kell lássam, hogy nálunk 2 Unranked, 2 Silver, 1 Gold, enemy ben 2 Gold, 1 Diamond, 1 Unranked, 1 Plat ? Nem tudom milyen DIV et érdemelnék, de gondolom m1 hogy van vagy nincs, a rendszer úgyis úgy dob össze az emberekkel ahogy akar... Azt viszont tudom hogy a rossz fókuszálás több célpontra, a lassú reflexek miatt talán ki sem kerülnék Bronze ból, hát ez van, de akkor mért teszi azt még a Riot hogy Platosokkal és a felett állókkal kell megmérkőznöm? Hol vagyok én hozzájuk, ez így nem fair. És ez nem csupán ARAM on van, volt ez SR ben is (ott ha nálunk jobbak voltak, kb semmi esély nem volt, nah ez már idegesítő). Ez csak egy játék, és csupán FUN, de hogyan lehetne szórakozni benne, ha az ember ellen folyton olyan Rankedeseket dob be a gép, akikkel nem nagyon bírni? Annyira sokoldalúak a meccsek hogy az már bosszantó, mert van hogy lehozom, van hogy csak feedelek. Átlag norm statom van, de nem ez számít, a meccs legyen megnyerve, ezen az elven vagyok. Az ARAM mondjuk olyan mod, ami igencsak unfair módon dobhat össze az emberekkel, egyrészt mert nem tudni kik ellen megyünk, másrészt meg azért mert igencsak rossz, és egyúttal eléggé OP csapatösszeállítások is születhetnek. PL az egyik csapat full GOLD és rossz hősök, a másik full Silver, de nagyon jó csapatösszeállítást kapnak, és akár 12 p alatt leverik őket. Szóval most okés hogy pont ezt a mod ot hoztam fel, de nem csak ARAM ban vannak Unfair meccsek.\nMi a ti véleményetek, nektek jó a mostani helyzet vagy ti sem vagytok vele megbékélve?","replies":[{"poster":"EUNE gets Rekt","date":"2015-08-16T17:53:33.302+0000","up_votes":2,"down_votes":0,"body":"Köszönöm a jelentésed, továbbítom az észrevétetleid.\n@Bsajt: nyugodtan lehet ide is bugokat/glitcheket jelenteni, én ezeket mind továbbítom.","replies":[]},{"poster":"Vasipari Béla","date":"2015-08-16T12:37:13.791+0000","up_votes":2,"down_votes":1,"body":"Ezt a fórumot Riotosok ritkán látogatják, ha értesz angolul, akkor ajánlom, hogy redditre írd a bugok leírását, arra fel szoktak figyelni, ha elég +1-et kap.","replies":[]},{"poster":"Ancromek","date":"2015-08-17T06:09:27.269+0000","up_votes":1,"down_votes":0,"body":"Én azt vettem észre hogy amikor a térképre kattintok akkor a hős néha (nagyon ritkán) elkezd egy kört tenni maga körül illetve néha megáll vagy olyan is van hogy egy másik útvonalon halad hollott ugyan oda nyomsz.","replies":[]},{"poster":"CrissTo","date":"2015-08-17T05:05:43.185+0000","up_votes":1,"down_votes":0,"body":"Én egy buggot észre vettem a shopban, ha egy itemset gyorsan vissza adok és utána újra ráütök ugyan arra a tárgyra, akkor a pénzt úgy mutatja, mint ha nem vonná le és ugyan az a pénz összeg megmaradna.","replies":[]},{"poster":"Tazsam","date":"2015-08-16T21:46:57.521+0000","up_votes":1,"down_votes":0,"body":"Ha már így bugok, sutyerák bizonyos skillektől teljesen tönkremegy, a trundle e pl. ilyen, elé dobod a jéghegyet és megáll amíg ott a hegy, meg se próbálja kikerülni, de ha jól emlékszem a singed e+w kombó is hasonlóan befagyasztja.","replies":[]}]} |
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{"poster":"Lord Sesshomaru","date":"2017-09-24T01:35:00.986+0000","title":"Why give champs with lots of mobility, high movement speed also?","subforum":"Miscellaneous","up_votes":1,"down_votes":0,"body":"Hmmmm, champs whose power comes from them quickly dashing around the battlefield:\n\n**Akali:** 3 dashes, 1 blink, **350 ms.**\n**Yasuo:** ∞ dashes, **345 ms.**\n**Lee Sin:** 2 dashes, **345 ms.**\n**Katarina:** resetting blink, **340 ms.**\n**Kassadin:** 1.2 sec cd blink, **340 ms.**\n**Ekko:** 1 dash, 1 blink, 1 teleport, **340 ms.**\n**Diana:** 2 dashes, **340 ms.**\n**Zed:** 1 dash, 1 blink-thing? 2 reverse blinks. **345 ms.**\n**Riven:** 4 dashes, **340 ms.**\n**Vi:** 2 dashes, **340 ms.**\n**Rengar:** God only knows, **345 ms.**\n\n\nOk, now lets look at some champs who have no dashes and rely exclusively on movement speed for positioning:\n\n**Anivia:** No dashes, **325 ms.**\n**Mordekaiser:** No dashes, **325 ms.**\n**Ziggs:** 1 semi-dash pretty much only useful for disengaging, **325 ms.**\n**Xayah:** No dashes, **325 ms.**\n\n\nWhat about champs who's entire kit revolves around moving around the map as fast as they can in order to try and be strong:\n\n**Aurelion Sol:** No dashes, **325 ms.**\n**Bard:** No dashes, **330 ms.**\n**Taliyah:** No dashes, **325 ms.**\n**KIndred:** 1 dash, **325 ms.**\n\n\nSo if you are already mobile, why should you also have greater map pressure and chasing potential?\nIf a Ziggs by some miracle manages to outplay all of Akali's 4 dashes, and get away, she still has enough move speed to just walk up to him and kill him anyway.\n\nWhat are champs like Anivia supposed to do against Ekko and Kassadin. She is already at a major disadvantage by being a squishy mage with no dashes, while they are Assassins pure-bred to kill her. All that happens is that she just gets absolutely blitzed by them every time. Why give them so much advantage?\n\nKindred has to constantly invade the enemy jungle, and the enemy knows exactly where she will be, she has to walk twice the distance than her opponent to get there, during a time when she is at her weakest, and she still has less move speed than already strong junglers like Lee Sin and Yi and Rengar. Honestly, what do you expect her to be able to do?\n\nI can understand giving artillery champs like Azir and Lux lower move speed because it'd be dumb if they never had to be near the fight in the first place, but still had an easy time getting away _(cough Xerath 340 ms cough)_. But it makes no sense to give extra mobility to those who are already the most mobile in the game, like Akali and Lee and Riven.\n\nWhy?\nI just want to know your reasoning behind this decision.","replies":[{"poster":"CHEESYLEEKS","date":"2017-09-24T05:51:36.336+0000","up_votes":1,"down_votes":0,"body":"{{champion:82}} has biggest boots in the game.... 325 ms\n\nseems about right.","replies":[{"poster":"Miicka","date":"2017-10-01T07:48:04.628+0000","up_votes":2,"down_votes":0,"body":"Yeah but his armour is thicc af so it slows him down.","replies":[]}]},{"poster":"Plasmarine","date":"2017-10-01T07:32:20.343+0000","up_votes":1,"down_votes":0,"body":"Every single one of the first 11 champions you mentioned are melee. Melee champs get more MS. Das basically it yo.\nIf they had less MS than ranged champions they would get constantly harassed by auto's in laning phase.","replies":[]},{"poster":"xReverie","date":"2017-09-24T04:25:29.974+0000","up_votes":1,"down_votes":0,"body":"Must have a formula - those that are melee get more movement speed, those with more range less movement speed.","replies":[{"poster":"xReverie","date":"2017-09-24T04:30:54.606+0000","up_votes":1,"down_votes":0,"body":"> [{quoted}](name=Reverie Soul,realm=OCE,application-id=Ntey9fRZ,discussion-id=ZlxdEuI8,comment-id=0002,timestamp=2017-09-24T04:25:29.974+0000)\n>\n> Must have a formula - those that are melee get more movement speed, those with more range less movement speed.\n\nThose also with an escape, or other source of movement speed from passives or abilities that are also ranged must also get less (eg: corki, jhin on initial release)","replies":[]}]},{"poster":"Akkordian Zoeve","date":"2017-09-24T01:42:36.223+0000","up_votes":1,"down_votes":0,"body":"To be fair, A Sol takes MS in his runes (I'm pretty sure). \n\nYou also left out Hecarim. He's VERY movement speed reliant. \n\nRework Janna will also be on the same lines. \n\nEve has 340 MS and has a Speed Up + Slow Removal. Not to mention several items in her kit give her a lot of movement speed for roams.","replies":[{"poster":"Lord Sesshomaru","date":"2017-09-24T03:32:11.553+0000","up_votes":1,"down_votes":0,"body":"Yea he has to take MS runes, otherwise everyone is faster than him before the game even starts. And for a champion whose entire kit revolves around moving, you need every bit of speed you can get.\n\nThats true about eve, but she doesn't have in-combat mobility the same way Kat or Lee does. In my opinion Evelynn is a very good example of how a champ should be in terms of map-pressure vs combat strength. The point of Evelynn is not to be good in a fight, her point is to give her team map pressure. She's fast and shes invisible, and thats a scary thing.\n\nIn reality she comes into lane and gets burst down immediately. But its the fear of her that makes her useful.\n\nThe problem is, Lee Sin is just as fast as Eve, but he's way better in a fight.\nSo he contributes a similar amount of pressure, but is also much more useful in other situations.","replies":[]}]},{"poster":"Klavinmour","date":"2017-09-24T02:35:45.944+0000","up_votes":1,"down_votes":0,"body":"I can tell ya, Diana, Rengar and Vi feel incredibly slow when you play them, especially when you're against their usual competition (from a jungler's perspective).\n\nKindred needs low movement speed because she's ranged and the way her kit plays out.\nIf you've seen a fed Kindred, you'll realise you don't want to see that moving at Pantheon's speed.\n\nAnivia, Ziggs and Xayah are very AoE centered, having LARGE area denial, and the ability to say \"you step in this zone here and you're fucked\".\nLike you said, Xerath has amazing long range power and the movespeed at the same time, though to be fair his bread and butter slows him to a crawl and his ultimate has him standing still.\n\nMordekaiser... he needs something, really the only one here I agree completely with, he's too slow, his kit is very much lumber towards the opponent and smack them slowly, he needs SOMETHING.\n\n--------------------------------------------------------\n\nBiggest problem here is that you're focusing too much on a singular piece of a champion's kit than their entire puzzle.\n\nOn paper Rengar and Diana have high mobility, but in practice they are pretty much jump in and succeed or you die/nothing happens.\nRengar especially, if you're knocked back by a Janna ult or Vayne Condemn, you're not reaching your target again, you wont be able to catch them.\n\nWhile champions like Aurelion Sol have very safe (if boring and uninspiring) kits, that allow them to deny large areas of play, typically around themselves, but have the draw back of slower movespeed to compensate.","replies":[{"poster":"Lord Sesshomaru","date":"2017-09-24T03:26:52.777+0000","up_votes":1,"down_votes":0,"body":"> I can tell ya, Diana, Rengar and Vi feel incredibly slow when you play them, \n\nIll gladly trade 'actually being slow' for 'feeling slow' any day.\n\n> If you've seen a fed Kindred, you'll realise you don't want to see that moving at Pantheon's speed.\n\nI dont want a pantheon coming at me at pantheon's speed!\n\nAgreed a fed Kindred is a scary thing _(as a kndred player, I know)_, but so is a fed Kat, and a fed Yasuo, and a fed Riven.\nThe difference being: that you don't see many fed Kindred's, because no one plays kindred, because nearly every jungler in the game does the same job but better. Apart from late game damage, Kindred doesn't actually offer much to the team, her ganks are lacklustre, her counter jungling is predictable, she can't solo objectives early. But jungling is an early game position, the point of a jungler is to win early game and get your lanes and objectives ahead, having a jungler that is only worth her salt in late game isn't actually much of a help.\n\n> Anivia, Ziggs and Xayah are very AoE centered, having LARGE area denial, and the ability to say \"you step in this zone here and you're fucked\".\n\nKatarina, Ekko, Zed, etc all have very proficient area denials as well. Katarina puts areas off limits way harder than Ziggs or Xayah does. But she's still allowed instant blinks and high ms.\n\nMordekaiser is the one and only champ in the game that I fully support a rework for. Everyone else _(strong or weak, underplayed or overplayed)_ at least has a clear idea of where they fit into the game. Morde just has no idea at all, the only efficient way to play Morde is as the farming half of a duo lane, _(and unless you want a very angry marksman on your ass)_ ADC is the only role that fits into, and quiet frankly there could be no worse position to take him in than in a lane against 2 ranged champions with cc.\n\n> Rengar especially, if you're knocked back by a Janna ult or Vayne Condemn, you're not reaching your target again, you wont be able to catch them.\n\nYes thats true, unless you get pushed back into a bush as rengar, you probably won't reach your target again. However you were in top lane 30 seconds ago, and now you're in bot, because for some reason you have the capability to leap on your opponent **as well as** cross the map faster than most other junglers. \n\nWhere as someone like anivia wont get pushed back by Vayne. One, because she can't dash in in the first place, and two, because she's still in river flapping her wings trying to actually get to the fight!\n\n> but have the draw back of slower movespeed to compensate.\n\nWhat exactly is Aurelion Sol compensating for? The fact that if you have a dash, he's fucked? The fact that if you have higher movement speed than him, he's fucked? The fact that if you have cc, he's fucked? Yes he has high damage and zone control, but he's hardly without heavy compromises already.\n\nAurelion Sol is the very definition of 'champs with a clearly defined weakness' \nNow try and tell me what Lee Sin's 'clearly defined weakness' is. If you can prove that it's an easier weakness to exploit and outplay than Aurelion Sol's then maybe ill accept you justifying him having more movement speed.\n\n_____________\n\nBut this isn't about giving slow people more movement speed, it's about asking why champions who are very strong in battle due to their combat mobility, also get great map pressure. While champs who's kits and play styles rely on map pressure, get shit all movement speed.","replies":[]}]}]} |
{"poster":"heizung1001","date":"2015-07-04T18:08:56.512+0000","title":"Rankedteam sucht Coach","subforum":"Clans & Teams","up_votes":1,"down_votes":0,"body":"Hallo,\r\nwir sind die GinyuForce wir suchen einen Coach.\r\nzu Uns:\r\nTeams G3 & G5\r\nTop:G4\r\nJungle:G4\r\nMid:P5\r\nADC:G3\r\nSup:G5\r\nspielen zusammen seit 2 1/2 Monaten zusammen\r\nBei interesse einfach adden(heizung1001)\r\nMfG heizi","replies":[]} |
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"say": "빛을 못 받는 장소에 틀어박힌다니, 저, 걱정되네요……"
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"say": "…써! 뭡니까 이건! 너무 써서 눈물 나겠어요! 비터 초콜릿이 들어간 거 아니에요?!"
},
{
"say": "후우…… '말차' 의 맛…… 역시 독특하네요…… ",
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"side": 0,
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"say": "그러고 보니, 아카츠키는 아직 안 왔나요? 오늘은 비번이라 들었는데……"
},
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"say": "아카츠키는……"
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"say": "편지를 남기고 홀로 외출했다나봐!"
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{"pmid":32492991,"title":"Utility of lateral flow tests in SARS-CoV-2 infection monitorization.","text":["Utility of lateral flow tests in SARS-CoV-2 infection monitorization.","OBJECTIVE: The diagnosis of SARS-CoV-2 infection is crucial for medical and public health reasons, to allow the best treatment of cases and the best control of the pandemic. Serology testing allows for the detection of asymptomatic infections and 19-COVID cases once the virus has been cleared. We analyzed the usefulness of the SARS-CoV-2 rapid test of Autobio and tried to correlate its pattern with the severity of COVID19 infection. METHODS: We analyzed the accuracy and clinical usefulness of a point-of-care IgM and/or IgG test for SARS-CoV-2 in 35 COVID-19 patients [12 (34.3%) mild-moderate and 23 (65.7%) severe-critical] admitted to a field hospital in Madrid, as well as in 5 controls. RESULTS: The mean time from the first day of symptoms to the antibody test was 28 days (SD: 8.7), similar according to the severity of the disease. All patients with SARS-CoV-2 PCR+ showed the corresponding IgG positivity, while these results were negative in all control individuals. A total of 26 (74%) cases also presented with positive IgM, 19 (83%) were severe-critical cases and 7 (58%) were mild-moderate cases. The IgM response lasted longer in the severe critical cases (mean: 29.7 days; SD: 8.4) compared to the moderate cases (mean: 21.2 days; SD: 2.0).. CONCLUSIONS: Rapid serology tests are useful for the diagnosis of patients with COVID-19 (mainly IgG detection) and may also be correlated with the severity of the infection (based on IgM detection).","Rev Esp Quimioter","Candel, F J","Vinuela-Prieto, J M","Gonzalez Del Castillo, J","Barreiro Garcia, P","Fragiel Saavedra, M","Hernandez Piriz, A","Jimenez Virumbrales, D","Canora Lebrato, J","Garcia de Casasola, G","Gil Prieto, R","San-Roman Montero, J","Ortega Anselmi, J","Barba Martin, R","Prados Roa, F","Marco Martinez, J","Zapatero Gaviria, A","32492991"],"abstract":["OBJECTIVE: The diagnosis of SARS-CoV-2 infection is crucial for medical and public health reasons, to allow the best treatment of cases and the best control of the pandemic. Serology testing allows for the detection of asymptomatic infections and 19-COVID cases once the virus has been cleared. We analyzed the usefulness of the SARS-CoV-2 rapid test of Autobio and tried to correlate its pattern with the severity of COVID19 infection. METHODS: We analyzed the accuracy and clinical usefulness of a point-of-care IgM and/or IgG test for SARS-CoV-2 in 35 COVID-19 patients [12 (34.3%) mild-moderate and 23 (65.7%) severe-critical] admitted to a field hospital in Madrid, as well as in 5 controls. RESULTS: The mean time from the first day of symptoms to the antibody test was 28 days (SD: 8.7), similar according to the severity of the disease. All patients with SARS-CoV-2 PCR+ showed the corresponding IgG positivity, while these results were negative in all control individuals. A total of 26 (74%) cases also presented with positive IgM, 19 (83%) were severe-critical cases and 7 (58%) were mild-moderate cases. The IgM response lasted longer in the severe critical cases (mean: 29.7 days; SD: 8.4) compared to the moderate cases (mean: 21.2 days; SD: 2.0).. CONCLUSIONS: Rapid serology tests are useful for the diagnosis of patients with COVID-19 (mainly IgG detection) and may also be correlated with the severity of the infection (based on IgM detection)."],"journal":"Rev Esp Quimioter","authors":["Candel, F J","Vinuela-Prieto, J M","Gonzalez Del Castillo, J","Barreiro Garcia, P","Fragiel Saavedra, M","Hernandez Piriz, A","Jimenez Virumbrales, D","Canora Lebrato, J","Garcia de Casasola, G","Gil Prieto, R","San-Roman Montero, J","Ortega Anselmi, J","Barba Martin, R","Prados Roa, F","Marco Martinez, J","Zapatero Gaviria, A"],"date":"2020-06-05T11:00:00Z","year":2020,"_id":"32492991","source":"PubMed","week":"202023|Jun 01 - Jun 07","doi":"10.37201/req/052.2020","keywords":["autobio","covid-19 infection","sars-cov-2","serologic rapid tests","weak positive bands"],"locations":["Madrid"],"countries":["Spain"],"countries_codes":["ESP|Spain"],"topics":["Diagnosis"],"weight":1,"_version_":1668712823914496001,"score":9.490897,"similar":[{"pmid":32504945,"title":"Alltest rapid lateral flow immunoassays is reliable in diagnosing SARS-CoV-2 infection from 14 days after symptom onset: A prospective single-center study.","text":["Alltest rapid lateral flow immunoassays is reliable in diagnosing SARS-CoV-2 infection from 14 days after symptom onset: A prospective single-center study.","OBJECTIVES: SARS-CoV-2 infection diagnosis is challenging in patients from 2 to 3 weeks after the onset of symptoms, due to the low positivity rate of the PCR. Serologic tests could be complementary to PCR in these situations. The aim of our study was to analyze the diagnostic performance of one serologic rapid test in COVID-19 patients. METHODS: We evaluated a lateral flow immunoassay (AllTest COVID-19 IgG/IgM) which detects IgG and IgM antibodies. We validated the serologic test using serum samples from 100 negative patients (group 1) and 90 patients with COVID-19 confirmed by PCR (group 2). Then, we prospectively evaluated the test in 61 patients with clinical diagnosis of pneumonia of unknown etiology that were negative for SARS-CoV-2 by PCR (group 3). RESULTS: All 100 patients from group 1 were negative for the serologic test (specificity = 100 %). Regarding group 2 (PCR-positive), the median time from their symptom onset until testing was 17 days. For these 90 group-2 patients, the test was positive for either IgM or IgG in 58 (overall sensitivity = 64.4 %), and in patients tested 14 days or more after the onset of symptoms, the sensitivity was 88.0 %. Regarding the 61 group-3 patients, median time after symptom onset was also 17 days, and the test was positive in 54 (88.5 % positivity). CONCLUSIONS: Our study shows that Alltest lateral flow immunoassay is reliable as a complement of PCR to diagnose SARS-CoV-2 infection after 14 days from the onset of symptoms and in patients with pneumonia and negative PCR for SARS-CoV-2.","J Clin Virol","Perez-Garcia, Felipe","Perez-Tanoira, Ramon","Romanyk, Juan","Arroyo, Teresa","Gomez-Herruz, Pena","Cuadros-Gonzalez, Juan","32504945"],"abstract":["OBJECTIVES: SARS-CoV-2 infection diagnosis is challenging in patients from 2 to 3 weeks after the onset of symptoms, due to the low positivity rate of the PCR. Serologic tests could be complementary to PCR in these situations. The aim of our study was to analyze the diagnostic performance of one serologic rapid test in COVID-19 patients. METHODS: We evaluated a lateral flow immunoassay (AllTest COVID-19 IgG/IgM) which detects IgG and IgM antibodies. We validated the serologic test using serum samples from 100 negative patients (group 1) and 90 patients with COVID-19 confirmed by PCR (group 2). Then, we prospectively evaluated the test in 61 patients with clinical diagnosis of pneumonia of unknown etiology that were negative for SARS-CoV-2 by PCR (group 3). RESULTS: All 100 patients from group 1 were negative for the serologic test (specificity = 100 %). Regarding group 2 (PCR-positive), the median time from their symptom onset until testing was 17 days. For these 90 group-2 patients, the test was positive for either IgM or IgG in 58 (overall sensitivity = 64.4 %), and in patients tested 14 days or more after the onset of symptoms, the sensitivity was 88.0 %. Regarding the 61 group-3 patients, median time after symptom onset was also 17 days, and the test was positive in 54 (88.5 % positivity). CONCLUSIONS: Our study shows that Alltest lateral flow immunoassay is reliable as a complement of PCR to diagnose SARS-CoV-2 infection after 14 days from the onset of symptoms and in patients with pneumonia and negative PCR for SARS-CoV-2."],"journal":"J Clin Virol","authors":["Perez-Garcia, Felipe","Perez-Tanoira, Ramon","Romanyk, Juan","Arroyo, Teresa","Gomez-Herruz, Pena","Cuadros-Gonzalez, Juan"],"date":"2020-06-07T11:00:00Z","year":2020,"_id":"32504945","source":"PubMed","week":"202023|Jun 01 - Jun 07","doi":"10.1016/j.jcv.2020.104473","keywords":["alltest","covid-19","diagnosis","lateral flow immunoassay","sars-cov-2","serologic rapid test"],"topics":["Diagnosis"],"weight":1,"_version_":1668892488225521665,"score":232.6442},{"pmid":32403010,"title":"Evaluation of two automated and three rapid lateral flow immunoassays for the detection of anti-SARS-CoV-2 antibodies.","text":["Evaluation of two automated and three rapid lateral flow immunoassays for the detection of anti-SARS-CoV-2 antibodies.","INTRODUCTION: Several SARS-CoV-2 immunoassays have been developed recently. The purpose of this study was to assess the performance of five immunoassays for the detection of SARS-CoV-2 antibodies. METHODS: Two quantitative automated immunoassays (Maglumi2019-n-Cov IgG and IgM and Euroimmun Anti-SARS-CoV-2 IgG and IgA assays) and three lateral flow rapid tests were performed. This retrospective study included 200 residual sera from patients and healthy volunteers. Case serum samples (n = 128) were obtained from COVID-19 patients confirmed by RT-qPCR and CT-scan. Days since onset of symptoms was collected from their medical records. Control non-SARS-CoV-2 samples (n = 72) were obtained from anonymous stored residual serum samples. RESULTS: Maglumi IgG/IgM tests showed overall less sensitivity than Euroimmun IgG/IgA test (84.4 % versus 64.3 %). Both tests showed similar specificities of IgG at 99 % and 100 %, respectively. The two tests showed similar specificity for IgG at 99 % and 100 %, respectively. The results from the lateral flow assays were easily interpretable with unambiguous coloured reading bands. The overall sensitivity of the three tests was similar (around 70 %) without any significant differences. The sensitivity of the three lateral flow assays and also of the serological quantitative assays increased during the second week after symptom onset and all reached similar values (91 %-94 %) after 14 days. CONCLUSION: This study shows accurate and equivalent performance of the five serological antibody assays (ELISA, CLIA and three lateral flow tests) in detecting SARS-CoV-2 antibodies 14 days after the onset of COVID-19 symptoms. This is compatible with their application in specific clinical contexts and in determining epidemiological strategies for the COVID-19 pandemic.","J Clin Virol","Montesinos, Isabel","Gruson, Damien","Kabamba, Benoit","Dahma, Hafid","Van den Wijngaert, Sigi","Reza, Soleimani","Carbone, Vincenzo","Vandenberg, Olivier","Gulbis, Beatrice","Wolff, Fleur","Rodriguez-Villalobos, Hector","32403010"],"abstract":["INTRODUCTION: Several SARS-CoV-2 immunoassays have been developed recently. The purpose of this study was to assess the performance of five immunoassays for the detection of SARS-CoV-2 antibodies. METHODS: Two quantitative automated immunoassays (Maglumi2019-n-Cov IgG and IgM and Euroimmun Anti-SARS-CoV-2 IgG and IgA assays) and three lateral flow rapid tests were performed. This retrospective study included 200 residual sera from patients and healthy volunteers. Case serum samples (n = 128) were obtained from COVID-19 patients confirmed by RT-qPCR and CT-scan. Days since onset of symptoms was collected from their medical records. Control non-SARS-CoV-2 samples (n = 72) were obtained from anonymous stored residual serum samples. RESULTS: Maglumi IgG/IgM tests showed overall less sensitivity than Euroimmun IgG/IgA test (84.4 % versus 64.3 %). Both tests showed similar specificities of IgG at 99 % and 100 %, respectively. The two tests showed similar specificity for IgG at 99 % and 100 %, respectively. The results from the lateral flow assays were easily interpretable with unambiguous coloured reading bands. The overall sensitivity of the three tests was similar (around 70 %) without any significant differences. The sensitivity of the three lateral flow assays and also of the serological quantitative assays increased during the second week after symptom onset and all reached similar values (91 %-94 %) after 14 days. CONCLUSION: This study shows accurate and equivalent performance of the five serological antibody assays (ELISA, CLIA and three lateral flow tests) in detecting SARS-CoV-2 antibodies 14 days after the onset of COVID-19 symptoms. This is compatible with their application in specific clinical contexts and in determining epidemiological strategies for the COVID-19 pandemic."],"journal":"J Clin Virol","authors":["Montesinos, Isabel","Gruson, Damien","Kabamba, Benoit","Dahma, Hafid","Van den Wijngaert, Sigi","Reza, Soleimani","Carbone, Vincenzo","Vandenberg, Olivier","Gulbis, Beatrice","Wolff, Fleur","Rodriguez-Villalobos, Hector"],"date":"2020-05-14T11:00:00Z","year":2020,"_id":"32403010","source":"PubMed","week":"202020|May 11 - May 17","doi":"10.1016/j.jcv.2020.104413","keywords":["clia","covid-19","elisa","immunoassays","lateral flow assays","sars-cov-2"],"locations":["IgA assays"],"topics":["Diagnosis"],"weight":1,"_version_":1666714494891458563,"score":219.72688},{"pmid":32428207,"title":"Longitudinal Monitoring of SARS-CoV-2 IgM and IgG Seropositivity to Detect COVID-19.","text":["Longitudinal Monitoring of SARS-CoV-2 IgM and IgG Seropositivity to Detect COVID-19.","BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a novel beta-coronavirus that has recently emerged as the cause of the 2019 coronavirus pandemic (COVID-19). Polymerase chain reaction (PCR) based tests are optimal and recommended for the diagnosis of an acute SARS-CoV-2 infection. Serology tests for viral antibodies provide an important tool to diagnose previous exposure to the virus. Here we evaluate the analytical performance parameters of the Diazyme SARS-CoV-2 IgM/IgG serology assays and describe the kinetics of IgM and IgG seroconversion observed in patients with PCR confirmed COVID-19 who were admitted to our hospital. METHODS: We validated the performance of the Diazyme assay in 235 subjects to determine specificity. Subsequently, we evaluated the SARS-CoV-2 IgM and IgG seroconversion of 54 PCR confirmed COVID-19 patients and determined sensitivity of the assay at three different timeframes. RESULT: Sensitivity and specificity for detecting seropositivity at >/= 15 days following a positive SARS-CoV-2 PCR result, was 100.0% and 98.7% when assaying for the panel of IgM and IgG. The median time to seropositivity observed for a reactive IgM and IgG result from the date of a positive PCR was 5 days (IQR: 2.75-9 days) and 4 days (IQR: 2.75-6.75 days), respectively. CONCLUSIONS: Our data demonstrates that the Diazyme IgM/IgG assays are suited for the purpose of detecting SARS-CoV-2 IgG and IgM in patients with suspected SARS-CoV-2 infections. For the first time, we report longitudinal data showing the evolution of seroconversion for both IgG and IgM in a cohort of acutely ill patients in the United States. We also demonstrate a low false positive rate in patients who were presumed to be disease free.","J Appl Lab Med","Suhandynata, Raymond T","Hoffman, Melissa A","Kelner, Michael J","McLawhon, Ronald W","Reed, Sharon L","Fitzgerald, Robert L","32428207"],"abstract":["BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a novel beta-coronavirus that has recently emerged as the cause of the 2019 coronavirus pandemic (COVID-19). Polymerase chain reaction (PCR) based tests are optimal and recommended for the diagnosis of an acute SARS-CoV-2 infection. Serology tests for viral antibodies provide an important tool to diagnose previous exposure to the virus. Here we evaluate the analytical performance parameters of the Diazyme SARS-CoV-2 IgM/IgG serology assays and describe the kinetics of IgM and IgG seroconversion observed in patients with PCR confirmed COVID-19 who were admitted to our hospital. METHODS: We validated the performance of the Diazyme assay in 235 subjects to determine specificity. Subsequently, we evaluated the SARS-CoV-2 IgM and IgG seroconversion of 54 PCR confirmed COVID-19 patients and determined sensitivity of the assay at three different timeframes. RESULT: Sensitivity and specificity for detecting seropositivity at >/= 15 days following a positive SARS-CoV-2 PCR result, was 100.0% and 98.7% when assaying for the panel of IgM and IgG. The median time to seropositivity observed for a reactive IgM and IgG result from the date of a positive PCR was 5 days (IQR: 2.75-9 days) and 4 days (IQR: 2.75-6.75 days), respectively. CONCLUSIONS: Our data demonstrates that the Diazyme IgM/IgG assays are suited for the purpose of detecting SARS-CoV-2 IgG and IgM in patients with suspected SARS-CoV-2 infections. For the first time, we report longitudinal data showing the evolution of seroconversion for both IgG and IgM in a cohort of acutely ill patients in the United States. We also demonstrate a low false positive rate in patients who were presumed to be disease free."],"journal":"J Appl Lab Med","authors":["Suhandynata, Raymond T","Hoffman, Melissa A","Kelner, Michael J","McLawhon, Ronald W","Reed, Sharon L","Fitzgerald, Robert L"],"date":"2020-05-20T11:00:00Z","year":2020,"_id":"32428207","source":"PubMed","week":"202021|May 18 - May 24","doi":"10.1093/jalm/jfaa079","keywords":["covid-19","sars-cov-2","antibody","diagnosis","serology"],"locations":["United States"],"countries":["United States"],"countries_codes":["USA|United States"],"topics":["Diagnosis"],"weight":1,"_version_":1667352728708317184,"score":209.1415},{"pmid":32363011,"pmcid":"PMC7178815","title":"Evaluation of a COVID-19 IgM and IgG rapid test; an efficient tool for assessment of past exposure to SARS-CoV-2.","text":["Evaluation of a COVID-19 IgM and IgG rapid test; an efficient tool for assessment of past exposure to SARS-CoV-2.","COVID-19 is the most rapidly growing pandemic in modern time, and the need for serological testing is most urgent. Although the diagnostics of acute patients by RT-PCR is both efficient and specific, we are also crucially in need of serological tools for investigating antibody responses and assessing individual and potential herd immunity. We evaluated a commercially available test developed for rapid (within 15 minutes) detection of SARS-CoV-2-specific IgM and IgG by 29 PCR-confirmed COVID-19 cases and 124 negative controls. The results revealed a sensitivity of 69% and 93.1% for IgM and IgG, respectively, based solely on PCR-positivity due to the absence of a serological gold standard. The assay specificities were shown to be 100% for IgM and 99.2% for IgG. This indicates that the test is suitable for assessing previous virus exposure, although negative results may be unreliable during the first weeks after infection. More detailed studies on antibody responses during and post infection are urgently needed.","Infect Ecol Epidemiol","Hoffman, Tove","Nissen, Karolina","Krambrich, Janina","Ronnberg, Bengt","Akaberi, Dario","Esmaeilzadeh, Mouna","Salaneck, Erik","Lindahl, Johanna","Lundkvist, Ake","32363011"],"abstract":["COVID-19 is the most rapidly growing pandemic in modern time, and the need for serological testing is most urgent. Although the diagnostics of acute patients by RT-PCR is both efficient and specific, we are also crucially in need of serological tools for investigating antibody responses and assessing individual and potential herd immunity. We evaluated a commercially available test developed for rapid (within 15 minutes) detection of SARS-CoV-2-specific IgM and IgG by 29 PCR-confirmed COVID-19 cases and 124 negative controls. The results revealed a sensitivity of 69% and 93.1% for IgM and IgG, respectively, based solely on PCR-positivity due to the absence of a serological gold standard. The assay specificities were shown to be 100% for IgM and 99.2% for IgG. This indicates that the test is suitable for assessing previous virus exposure, although negative results may be unreliable during the first weeks after infection. More detailed studies on antibody responses during and post infection are urgently needed."],"journal":"Infect Ecol Epidemiol","authors":["Hoffman, Tove","Nissen, Karolina","Krambrich, Janina","Ronnberg, Bengt","Akaberi, Dario","Esmaeilzadeh, Mouna","Salaneck, Erik","Lindahl, Johanna","Lundkvist, Ake"],"date":"2020-05-05T11:00:00Z","year":2020,"_id":"32363011","source":"PubMed","week":"202019|May 04 - May 10","doi":"10.1080/20008686.2020.1754538","keywords":["covid-19","igg","igm","diagnostics","rapid test","sars-cov-2"],"topics":["Diagnosis"],"weight":1,"_version_":1666138496024182784,"score":207.9221},{"pmid":32501411,"pmcid":"PMC7249039","title":"SARS-CoV-2 infection serology: a useful tool to overcome lockdown?","text":["SARS-CoV-2 infection serology: a useful tool to overcome lockdown?","The outbreak of 2019 novel coronavirus disease (Covid-19) caused by SARS-CoV-2 has spread rapidly, inducing a progressive growth in infected patients number. Social isolation (lockdown) has been assessed to prevent and control virus diffusion, leading to a worldwide financial and political crisis. Currently, SARS-CoV-2 RNA detection in nasopharyngeal swab takes place by real-time PCR (RT-qPCR). However, molecular tests can give some false-negative results. In this context, serological assays can be useful to detect IgG/IgM antibodies, to assess the degree of immunization, to trace the contacts, and to support the decision to re-admit people at work. A lot of serological diagnostic kits have been proposed on the market but validation studies have not been published for many of them. The aim of our work was to compare and to evaluate different assays analytical performances (two different immunochromatographic cards, an immunofluorescence chromatographic card, and a chemiluminescence-automated immunoassay) on 43 positive samples with RT-qPCR-confirmed SARS-CoV-2 infection and 40 negative control subjects. Our data display excellent IgG/IgM specificities for all the immunocromatographic card tests (100% IgG and 100% IgM) and for the chemiluminescence-automated assay (100% IgG and 94% IgM); IgG/IgM sensitivities are moderately lower for all methods, probably due to the assay viral antigen's nature and/or to the detection time of nasopharyngeal swab RT-qPCR, with respect to symptoms onset. Given that sensitivities (around 94% and 84% for IgG and IgM, respectively) implicate false-negative cases and given the lack of effective vaccines or treatments, the only currently available procedure to reduce SARS-CoV-2 transmission is to identify and isolate persons who are contagious. For this reason, we would like to submit a flowchart in which serological tests, integrated with nasopharyngeal swab RT-qPCR, are included to help social and work activities implementation after the pandemic acute phase and to overcome lockdown.","Cell Death Discov","Nuccetelli, Marzia","Pieri, Massimo","Grelli, Sandro","Ciotti, Marco","Miano, Roberto","Andreoni, Massimo","Bernardini, Sergio","32501411"],"abstract":["The outbreak of 2019 novel coronavirus disease (Covid-19) caused by SARS-CoV-2 has spread rapidly, inducing a progressive growth in infected patients number. Social isolation (lockdown) has been assessed to prevent and control virus diffusion, leading to a worldwide financial and political crisis. Currently, SARS-CoV-2 RNA detection in nasopharyngeal swab takes place by real-time PCR (RT-qPCR). However, molecular tests can give some false-negative results. In this context, serological assays can be useful to detect IgG/IgM antibodies, to assess the degree of immunization, to trace the contacts, and to support the decision to re-admit people at work. A lot of serological diagnostic kits have been proposed on the market but validation studies have not been published for many of them. The aim of our work was to compare and to evaluate different assays analytical performances (two different immunochromatographic cards, an immunofluorescence chromatographic card, and a chemiluminescence-automated immunoassay) on 43 positive samples with RT-qPCR-confirmed SARS-CoV-2 infection and 40 negative control subjects. Our data display excellent IgG/IgM specificities for all the immunocromatographic card tests (100% IgG and 100% IgM) and for the chemiluminescence-automated assay (100% IgG and 94% IgM); IgG/IgM sensitivities are moderately lower for all methods, probably due to the assay viral antigen's nature and/or to the detection time of nasopharyngeal swab RT-qPCR, with respect to symptoms onset. Given that sensitivities (around 94% and 84% for IgG and IgM, respectively) implicate false-negative cases and given the lack of effective vaccines or treatments, the only currently available procedure to reduce SARS-CoV-2 transmission is to identify and isolate persons who are contagious. For this reason, we would like to submit a flowchart in which serological tests, integrated with nasopharyngeal swab RT-qPCR, are included to help social and work activities implementation after the pandemic acute phase and to overcome lockdown."],"journal":"Cell Death Discov","authors":["Nuccetelli, Marzia","Pieri, Massimo","Grelli, Sandro","Ciotti, Marco","Miano, Roberto","Andreoni, Massimo","Bernardini, Sergio"],"date":"2020-06-06T11:00:00Z","year":2020,"_id":"32501411","source":"PubMed","week":"202023|Jun 01 - Jun 07","doi":"10.1038/s41420-020-0275-2","keywords":["immunochemistry","viral infection"],"topics":["Diagnosis"],"weight":1,"_version_":1668890966448144384,"score":200.2822}]} |
{"poster":"eRoxTX","date":"2017-10-12T14:08:12.226+0000","title":"{LFM} - FlexQ Evening [2/5] Dia+","subforum":"Clans & Teams","up_votes":1,"down_votes":0,"body":"**Guten Abend Liebes League of Legends Forum,**\r\n\r\nSuche eine Gruppe für FlexQ DIA rush, heute Abend wie auch andere Tage.\r\n\r\nSoloQ Rank: *Dia / High plat*\r\nFlexQ Rank: *Platin / Gold*\r\nZeit: *17.00 Uhr*\r\n\r\nTOP: Open!\r\nJNG: Open!\r\nMID: eRoxTX\r\nADC: Open!\r\nSUP: Open!\r\n\r\nKommunikation durch Teamspeak\r\nADD Ingame: eRoxTX oder schreibt eure Position unter diesen Thread\r\n\r\n**Mit freundlichen Grüssen**\r\n*eRoxtX*","replies":[]} |
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}
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{"poster":"Νοva","date":"2019-06-10T14:42:07.915+0000","title":"Suchen Botlane für Flex ab Dia2","subforum":"Clans & Teams","up_votes":1,"down_votes":0,"body":"Deai with it adden","replies":[]} |
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{"response": {"status": "ok", "userTier": "developer", "total": 1, "content": {"id": "sport/2006/aug/14/cricket.sport1", "type": "article", "sectionId": "sport", "sectionName": "Sport", "webPublicationDate": "2006-08-13T23:59:08Z", "webTitle": "Cricket:", "webUrl": "https://www.theguardian.com/sport/2006/aug/14/cricket.sport1", "apiUrl": "https://content.guardianapis.com/sport/2006/aug/14/cricket.sport1", "fields": {"headline": "Umpires admit they let Foxes get away with last-ball howler", "bodyText": "The umpires at the centre of the controversy in Saturday's Twenty20 final, Allan Jones and Peter Hartley, admitted last night that they had made a mistake in not calling the last delivery a no-ball. Nottinghamshire, hoping to become the first side to win the competition on their own ground, needed 11 runs from the final ball, bowled by Leicestershire's Jimmy Allenby. Will Smith hoisted the high full-toss over mid-on for six. 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Because everyone knows where the stumps are.\" When it comes to the height of the ball, the standing umpire looks to the square-leg umpire for guidance before making his own signal to the scorers. Hartley, the standing umpire on Saturday evening, said last night: \"I wish I had called a no-ball because I saw it on TV this morning and it was one, albeit a marginal one. \"But, if you didn't see it, you can't call it. I didn't pick up the height of the ball until it was hit. And the fact that it was hit to mid-on influenced my judgment a little. It is difficult to hit a high ball down the ground. It normally flies over square-leg or midwicket. \"The height rule, though, is when the batsman is standing upright and he is rarely upright when playing a stroke, so it is a difficult one, especially when the call is a tight one, as it was here.\" But the Nottinghamshire batsman Samit Patel felt the non-call denied them the opportunity of recording a remarkable victory. \"It was clearly a no-ball and it cost us the chance to win the final. We got so close,\" he said. In the circumstances, however, with glaring floodlights and driving rain, few people were prepared to give the umpires a hard time for getting such a marginal decision wrong and Mick Newell, the Notts coach, confirmed later that he would not be making a formal complaint. \"I think a no-ball should have been called and I'm disappointed because I thought it was fairly clear. But it happens. It was a tough situation and, if they don't see it, they don't see it.\" Leicestershire, though, deserved their title for playing the best cricket on finals day. Their total of 177 for two, with Darren Maddy top-scoring with 86 not out, was the highest score in the final of this competition. But Twenty20 cricket does not have a hoary history and it was really nothing more than a par score - four runs more in fact than they had made in their semi-final against Essex, a game they won by 23 runs. Their strength, though - apart from the prolific Maddy, the first batsman to score 1,000 runs in this competition - is in the field. They field like tigers and, with two spinners bowling a tight line, there is something of the old Gloucestershire in their one-day cricket. The captain Jeremy Snape, who once played at Nevil Road, has brought a huge influence with him. The success of Twenty20 is likely to lead to another increase in the number of matches in 2008 or 2009. 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{
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{
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{"$ref": "material_schema.json#"},
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}
]
},
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}
},
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},
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"items": {
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},
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},
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"items": {
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},
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},
"order": {
"description": "a property used to specify the rank in which perturbations are being applied to study subjects",
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}
}
}
]
}
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{"poster":"NicolásMorales","date":"2015-04-16T16:15:50.947+0000","title":"Eloboost","subforum":"Problemas Técnicos","up_votes":3,"down_votes":0,"body":"Rito pls, ya he mandado 3 tickets al soporte para denunciar un caso de eloboost, con pruebas. Pero las 3 veces solo me ha respondido una máquina con un mensaje automático de que verán el caso y bla bla bla, a los días después me llega un correo dando el caso como cerrado y pidiendome una evaluación del servicio, sin darme ninguna respuesta. De que sirve reportar el eloboost? hasta el día de hoy la cuenta que conozco le siguen haciendo eloboost, de hecho el dueño real de la cuenta es el que menos la ocupa. O es que no quieren hacer nada con esas cuentas porque ellos igual compran rp y skins, y así rito no sale perdiendo?\r\nOjalá alguien me responda esto y no me lo borren denuevo.","replies":[{"poster":"arturoo","date":"2015-04-16T17:28:46.176+0000","up_votes":3,"down_votes":1,"body":"a riot les importa un pépino esto solo le interesa el money de las skinn los que pagan eloboost son los que gasta mas dinero en el juego acaso riot quiere ban a esos? jajajaa ya riot me a borrado muchos msj diciendo verdades","replies":[]},{"poster":"AlexProgresiveX","date":"2017-05-11T18:13:03.779+0000","up_votes":1,"down_votes":0,"body":"Dejame decirte que estas bien equivocado. Yo fui uno de los baneados en la ola de baneos por eloboost del 2016, he comprado mucho RP incluso hasta el dia de hoy, riot no hace distinción ante estos casos. Si vez que no hacen nada, es por que no hay eloboost, asi de simple campeon. Dejame decirte que hacen bien su trabajo.\n\nYo me arrepiento de haberlo hecho, es mas, le pedi mis disculpas a riot personalmente y acepte mi castigo (recompensas de la season, icono, marco de oro), y a la comunidad tambien en un post.\n\nSimplemente en vez de criticar a los demas por que hacen algo prohibido, preocupate de ti. para eso esta el sistema de baneos, si vez algo reportalo y ya, pero no andes desesperado por ahi intentando que baneen a alguien injustificadamente.\n\nSaludos\n\npd: perdon la ortografia XDD","replies":[]},{"poster":"NicolásMorales","date":"2015-04-19T22:41:11.661+0000","up_votes":1,"down_votes":0,"body":"riot que debo hacer para reportar un caso de eloboost y que hagan algo?","replies":[]},{"poster":"NicolásMorales","date":"2015-04-17T03:07:48.769+0000","up_votes":1,"down_votes":0,"body":"ya me cansé de mandar tickets al support o hacer temas acá. No sirve de nada, no banean a los tóxicos, a los trolles, a los eloboost. Si compras RP y skins puedes hacer lo que quieras porque no te banearán {{champion:17}} {{item:3077}}","replies":[]},{"poster":"Kol Menzhur","date":"2015-04-16T23:54:31.131+0000","up_votes":1,"down_votes":0,"body":"Vos pensa que mi cuenta hoy tendria que ser unbaneada a la tarde y todavia sigo esperando jajaja","replies":[]},{"poster":"JaviSpike","date":"2015-04-16T18:32:47.860+0000","up_votes":1,"down_votes":0,"body":"estan haciendo un desastre con la comunidad en LAS directamente no les importa.","replies":[]}]} |
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{"title":"Big.Tit.Cream.Pie.13.2011.XXX.DVDRip.XviD-CiCXXX","uid":6826251,"size":2194325530,"categoryP":"porn","categoryS":"movies","magnet":"?xt=urn:btih:cbe5cc3cffd20a1808e9ccd02ae6af16929d94fb&dn=Big.Tit.Cream.Pie.13.2011.XXX.DVDRip.XviD-CiCXXX&tr=udp%3A%2F%2Ftracker.openbittorrent.com%3A80&tr=udp%3A%2F%2Fopen.demonii.com%3A1337&tr=udp%3A%2F%2Ftracker.coppersurfer.tk%3A6969&tr=udp%3A%2F%2Fexodus.desync.com%3A6969","seeders":0,"leechers":0,"uploader":"chkm8te","files":6,"time":1321573547,"description":"Screens: <a href="\nhttp://4ufrom.me/viewer.php?file=u6xt7cwc37qqnuoluovc.jpg" rel="nofollow" target="_NEW">\nhttp://4ufrom.me/viewer.php?file=u6xt7cwc37qqnuoluovc.jpg</a>\n <a href="\nhttp://4ufrom.me/viewer.php?file=wni2uyhkthud0kclqa9g.jpg" rel="nofollow" target="_NEW">\nhttp://4ufrom.me/viewer.php?file=wni2uyhkthud0kclqa9g.jpg</a>\n <a href="\nhttp://4ufrom.me/viewer.php?file=l48cidpn89tc9zatx1ej.jpg" rel="nofollow" target="_NEW">\nhttp://4ufrom.me/viewer.php?file=l48cidpn89tc9zatx1ej.jpg</a>\n <a href="\nhttp://4ufrom.me/viewer.php?file=7zfqhf9jfkxtv0vjxbpc.jpg" rel="nofollow" target="_NEW">\nhttp://4ufrom.me/viewer.php?file=7zfqhf9jfkxtv0vjxbpc.jpg</a>\n\n\nStarring: \tBridgette B., Capri Cavalli, Madelyn Marie, Nicole Aniston, Tacori Blu\nStudio: \tBangBros\nSeries: \tBig Tit Cream Pie\nGenre: \tBusty (Big Breast), Cream Pie, SexSex, Anal, Pretty Face, Beautiful Pussy, Doggy Style","torrent":{"xt":"urn:btih:cbe5cc3cffd20a1808e9ccd02ae6af16929d94fb","amp;dn":"Big.Tit.Cream.Pie.13.2011.XXX.DVDRip.XviD-CiCXXX","amp;tr":["udp%3A%2F%2Ftracker.openbittorrent.com%3A80","udp%3A%2F%2Fopen.demonii.com%3A1337","udp%3A%2F%2Ftracker.coppersurfer.tk%3A6969","udp%3A%2F%2Fexodus.desync.com%3A6969"],"infoHash":"cbe5cc3cffd20a1808e9ccd02ae6af16929d94fb","infoHashBuffer":{"type":"Buffer","data":[203,229,204,60,255,210,10,24,8,233,204,208,42,230,175,22,146,157,148,251]},"announce":[],"urlList":[]}} |
{"poster":"The BIack Canary","date":"2016-04-24T20:10:40.010+0000","title":"No puedo abrir el juego; PVP.net Patcher dejó de funcionar","subforum":"Charlas Generales","up_votes":1,"down_votes":0,"body":"Resulta que hoy a la mañana quise abrir el juego, pero me apareció un cartel que decía: "PVP.net Patcher Kernel dejó de funcionar" y me sigue saliendo eso.\r\nSi alguien tiene alguna solución se lo agradecería mucho.\r\n¡Muchas gracias!","replies":[{"poster":"fenakz","date":"2016-04-24T20:35:41.652+0000","up_votes":1,"down_votes":0,"body":"Tal vez esto te ayude \n\nhttp://boards.las.leagueoflegends.com/es/c/guias-y-consejos/0jucgA1Q-solucian-error-pvpnet-patcher-kernel-dejo-de-funcionar \n\nsaludos","replies":[]}]} |
[{"web_url": "https://www.nytimes.com/2017/03/03/opinion/sunday/why-we-believe-obvious-untruths.html", "source": "The New York Times", "_id": "58b9d21f95d0e024902fd6f0", "pub_date": "2017-03-03T20:29:09+0000", "lead_paragraph": "The problem is that the forces underlying bogus and real knowledge are similar.", "section_name": "Opinion", "type_of_material": "Op-Ed", "snippet": "The problem is that the forces underlying bogus and real knowledge are similar....", "document_type": "article", "headline": {"main": "Review: The Boston Symphony\u2019s Radiant Precision", "print_headline": "Savoring an Orchestral Overload"}}] |
{"poster":"SteamGameplay","date":"2016-06-10T15:50:03.636+0000","title":"Lyhiam, La Arquera del Pasillo","subforum":"Creaciones de la comunidad","up_votes":2,"down_votes":3,"body":"Muy Buenas a Todos, Hoy les presento mi 4to Concepto de Campeon ahora con:\r\n\r\n_**Lyhiam La Arquera del Pasillo**_\r\n\r\n**Región**: Jonias \r\n\r\n**Rol**: Tirador\r\n\r\n**Rol Secundario**: Luchador/Mago\r\n\r\n**Líneas**: Mid, Adc y Jungla\r\n\r\n**Idea del Campeón**: Me inspire en Varus y en Twisted Fate, ¿Por qué?, Ya lo verán ^^\r\n\r\n**Características**: Una Joven de Jonias, de Edad 27, su piel blanca, Lleva un traje que se divide por la parte izquierda del traje (Cubre todo su cuerpo de color Turquesa) y la parte derecha del traje (Cubre desde su muslo hasta su pecho de color Blanco), Pelo hasta su mentón de color negro, Su arco Que cubre casi todo su cuerpo (1 metro con 58 cm) y un carga flechas en su cintura (Contiene todas las flechas del campeón)\r\n\r\n**Lore**: Una joven Aprendiz del Gran Maestro, Varus, Escucho que su maestro lo nombraron Guardián del templo jonio.\r\nLuego de que se fuera Varus, Lyhiam decidió entrenar por su propia cuenta, en un Pasillo de su casa, Su Familia Estaba orgullosa de Lyhiam, ya que ellos mismo veían como Lyhiam progresaba con su arco.\r\nPero todo cambio cuando Noxus llego a jonias, Todo era caos, Lyhiam trato de proteger a su familia, pero Lyhiam entreno tanto en un pasillo que se le hacía complicado pelear en una zona totalmente abierta, no pudo proteger a sus aldeanos y Lyhiam, decepcionada, Fue al templo Jonio donde se encontraba Su maestro, El ver que no encontraba su maestro, Se tiro al suelo, llorando, siento una mano en su hombro, era un guardián del templo, le explico que Varus no volverá y tendría que salir rápidamente de ahí, él le enseño todas sus técnicas, y Lyhiam perfecciono las suyas, tanto, que pudo generar un pasillo con la madera de los arboles cercano, El Soldado tuvo que Volver al templo, ya que, aun podría liberarse la corrupción que se encontraba, Lyhiam ya casi una experta en el Arco, Fue a tomar venganza por los noxianos\r\n\r\n_\r\n\r\n**_Habilidades de la Campeona_\r\n**\r\n**Pasiva _(Vigilantes)_**: Lyhiam consigue** velocidad de movimiento** cuando se encuentra en **lugares cerrados** (Mayormente en la Jungla)\r\n\r\n**Q _(Flechas Pasaderas)_**: Lyhiam empieza a elegir unas de las** Flechas Pasaderas**.\r\nPodrán ser usadas mientras se encuentra en **Deslice del Callejón**\r\n**Flechas Pasaderas:\r\n**\r\n**-Flecha roja**: Canaliza la **Flecha Roja**, al lanzar la habilidad realiza **daño de ataque**, Si choca con un** campeón enemigo o una pared**, **Rebotara** (Siempre seguirá la dirección objetivo) **dependiendo** de la fuerza que se lanza\r\n\r\n**-Flecha Negra**: Canaliza la **Flecha Negra**, si esta choca con un **Campeón enemigo**, este quedara** Silenciado**\r\n\r\n**W _(Deslice del callejón)_**: Lyhiam se **desliza** hacia delante, Si el deslice choca con una **pared**, Esta empezara a** correr por esta pared** por unos segundos más y aumentara su **velocidad de ataque**\r\n\r\n**E _(Flechas Lentas)_:** Lyhiam empieza a elegir unas de las **Flechas Lentas**. Podrán ser usadas mientras se encuentra en **Deslice del Callejon**\r\n\r\n**Flechas Lentas:**\r\n\r\n**Flecha Café**: Canaliza la **Flecha Café**, al lanzar la habilidad realizara **daño mágico**, si choca con una **pared**, Este **seguirá** la pared durante unos segundos hasta encontrar un **campeón enemigo cercano** y irse **directamente** hacia él, si no encuentra a nadie, este **saldrá de la pared** y podrás **recogerla** para ganar** velocidad de movimiento** y se reducirá el **enfriamiento** de Flechas Lentas.\r\n\r\n **Flecha Azul**: Canaliza la **flecha azul,** al lanzarla **ralentiza** al enemigo que fue dado por la flecha, la ralentización **dependerá **de la fuerza que se lance.\r\n\r\n**R _(El Pasillo)_**: Luego de un lapso de **canalización**, Lyhiam genera un **pasillo** en la **dirección objetivo**, Si El Pasillo **choca con los enemigos**, Este los meterá **dentro** del Pasillo generado por Lyhiam.\r\n\r\nLas Habilidades de Lyhiam Interactúan con **El Pasillo**:\r\n\r\n**Flechas Pasaderas:\r\n**\r\n**-Flecha Roja**: esta **rebotara** hasta el **final **del pasillo\r\n\r\n**Deslice del Callejón**: Si Deslice del callejón** cocha **con unas de las **2 paredes generadas** por El Pasillo, Esta** correrá **por la pared hasta el **final **del callejón, Haciendo **daño mágico** al quien toque en el trayecto\r\n\r\n**Flechas Lentas:\r\n**\r\n**-Flecha Café**: Esta **avanzara** durante la pared hasta el **final** del pasillo hasta encontrar un** Campeón**, para luego ir **directamente** hacia él y genera **daño mágico en área\r\n**\r\n\r\nEspero que les guste esta Campeona, Cualquier duda o Idea Escribirlas Por favor, Gracias :D","replies":[{"poster":"Tipazo Humilde","date":"2016-06-11T02:16:57.452+0000","up_votes":1,"down_votes":0,"body":"Pasiva:bastante buena,no sé si sería tan eficiente para un adc,pero la idea está bien\n\nQ:creo que está bien\n\nW:bastante inútil para un adc\n\nE:¿es lo mismo que la Q?me suena a un poco vaga la idea de repetir la habilidad.\nCafé:la elección del color fue malísima,y solo puede interactuar con paredes ya que sino no vuelve para la velocidad de movimiento\nAzul:está bien\n\nR:bastante bien","replies":[{"poster":"SteamGameplay","date":"2016-06-11T14:31:24.260+0000","up_votes":1,"down_votes":0,"body":"Te explicare las habilidades brevemente\nPasiva: parece haberte gustado, sirve mas que nada para hacer roaming o gankear o llegar mas rapido a la linea\nQ: la flecha roja seria bastante eficiente en tf en lugares cerrados (en la jungla, dragon, baron, etc)\ny la flecha negria servira para poder hacer un gank correcto\nW: no le veo la deficiencia al campeon, si estas mal pocisionado con la campeona, utilizas w para retroceder, o poder utilizarlo ofensivamente mientras persigues a un enemigo \nE: ¿Por que nuevamente las elecciones de las flechas? Lo puse nuevamente por que sera bastante molestoso a la hora de combatir esperar tanto segundos para escojer una de las 4 flechas que saldrian en la Q por lo los separe, se hace mas comodo a la hora de las tf o duelos\nFlecha Cafe: esta es una flecha al estilo de la flecha roja, pero en vez de hacer daño de ataque, realiza daño magico, y no solo es en paredes, se explica que si choca con una pared esta avanzara hasta encontrar al enemigo, pero igualmente se podra tirar a los enemigos directamente (sin que recorra la pared) y la velocidad de movimiento, ¿que pasa si estas persiguiendo a un hecarim? es imposible de alcanzar al igual que singed, por lo el jugador tratata de darle con la flecha cafe por la pared a ver si consigue darle, y si no gana velocidad de movimiento y la posibilidad de usar la E para acercarse mas y poder llevarse la muerte\nR: creo que la entendiste, simplemente un pasillo (comparando con alguna habilidad, serian 2 ultis de taliyah que forman un pasillo)","replies":[{"poster":"Tipazo Humilde","date":"2016-06-15T21:24:26.708+0000","up_votes":1,"down_votes":0,"body":"Pasiva:no rinde en un adc,solo sirve en una situacion demasiado especifica\nW:no tiene utilidad lo de correr por la pared a un adc(ademas de que es imposible de hacerlo en el juego)\nE:es muy flojo repetir una habilidad,ese es el problema","replies":[{"poster":"SteamGameplay","date":"2016-06-15T21:46:34.786+0000","up_votes":1,"down_votes":0,"body":"Pasiva: Sirve para hacer roaming, estilo Quinn\nW: Si tiene utilidad, ya que puedes estar mal posicionado, correr hacia atras mientras cargas unas de las flechas de Lyhiam, y sobre correr en la pared, pared me refiero a cualquier cosa que no puedes traspasar\nE: Seria demasiado pesado tener 4 seleccion de flecha en una sola habilidad","replies":[{"poster":"Tipazo Humilde","date":"2016-06-16T03:41:21.938+0000","up_votes":1,"down_votes":0,"body":"pasiva:no,quinn puede hacer roaming,pero su ulti sirve para muchas otras cosas,esa pasiva tuya no rinde para nada en linea que es lo que importa en un adc,en la cicatriz de cristal ni siquiera serviría para nada\nW:pero si estas escapando lucian y graves pueden atravesar la pared,tu campeon se queda pegado ahí corriendo\nE:hay que arreglar eso,porque que dos habilidades sean iguales es muy flojo,es mejor tener las 4 en la Q o quitar alguna","replies":[]}]}]}]}]},{"poster":"Uro Ax","date":"2016-06-16T02:54:17.608+0000","up_votes":1,"down_votes":0,"body":"Sabes tu campeon no existe y nunca lo hará pero ya me imagino lo roto que sería y de adc no lo veo lo veo mid o jg y muy buena tu última,solo la e no me convence no sabria pero no me convence pero la ultima ej combo con la q la pensaste bien y tu w esta buena","replies":[]},{"poster":"FallenDemonX","date":"2016-06-11T18:52:36.679+0000","up_votes":1,"down_votes":0,"body":"Pasiva: Es la pasiva de Taliyah, pero sin tener que estar fuera de combate. \n\nQ: Me gusta mucho, la W de TF es una de mis skill favoritas y estaria genial poder verla en otro campeon. Tanto la Roja como la Negra tienen un rol claro en el kit y encajan muy bien.\n\nW: Ese momento genial en que alguien piensa igual que tu: http://boards.las.leagueoflegends.com/es/c/creaciones-de-la-comunidad/LZ6KOWWh-concepto-de-campean-tamara-la-mercenaria-de-las-sombras\n\n\n> W: Acrobacia del Sicario\n> \n> Costo: 65 cargas de Instinto de Supervivencia\n> CD: 17/16/15/13/12 segundos\n> Alcance: 400\n> \n> Pasiva: Por cada campeón enemigo cercano, obtiene 1 carga de Instinto de Supervivencia cada segundo, hasta un máximo de 100.\n> \n> Activa: Tamara se lanza hacia una dirección. Si impacta un enemigo, le inflige 50/65/80/95/105 (60% AD adicional) como daño físico y lo aturde por 1 segundo. Si choca con un muro podrá subirse a él y caminar sobre el muro durante 9/10/11/12/13 segundos, esto aumenta su rango de visión en 50/100/150/200/250. Pasado ese tiempo Tamara saltara al terreno bajo mas cercano automáticamente.\n> \n> Puede reactivar la habilidad para saltar a otro muro o al suelo consumiendo todas las cargas. Si impacta un campeón, se detiene y le inflige 40/60/80/100/120 (30% AD adicional) más un 4/5/6/7/8% de la vida máxima del objetivo como daño físico.\n> \n> Del Polvo Venimos: Adquiere visión verdadera por 4/5/6/7 segundos en un área de 250/400/550/700. \n\n\nE: Es un poco burdo repetir la habilidad, pero se ve por donde vas. Son flechas similares entre la Q y la E pero con su propio toque. La Azul me la imagino con un slow del 90%, me parece algo aburrida en comparacion pero tiene sentido.\n\nR: no hay mucho que decir, encaja muy bien y es una de esas ult en plan \"El momento ha llegado\". Me gusta mucho","replies":[{"poster":"SteamGameplay","date":"2016-06-11T21:39:32.753+0000","up_votes":1,"down_votes":0,"body":"Hola viejo amigo, me gustan tus criticas y tu forma de explicarlas, ademas, tus conceptos de campeon son muy buenas y bien explicadas (algo en que debo trabajar), me agrada verte de vuelta, y hablando sobre de que pensamos iguales, deberiamos crear un concepto de campeon juntos, a ver que sale haha","replies":[{"poster":"FallenDemonX","date":"2016-06-11T23:29:47.349+0000","up_votes":1,"down_votes":0,"body":"... Esto es vergonzoso ¿Quien sos?\n\nHaahah bue no importa, aqui nadie se conoce. Lo que importa es el amor al arte y a los juegos XD.\n\nGracias por cierto, me interesan mucho los conceptos de campeones y como a la gente se le ocurre cosas re locas. Tambien el comentar para ver si puedo a ayudar a mejorar a alguien, o solo echar buena onda y atencion. A todos les gusta tener atencion.\n\nAhora no mas iba a subir una \"preview\" de un concepto nuevo. Por ahora se llama \"Cifra\". Espero que te guste la historia.","replies":[{"poster":"SteamGameplay","date":"2016-06-12T00:44:26.723+0000","up_votes":1,"down_votes":0,"body":"Veré tu concepto de campeón ^^\n\nP.D: Aun no dices si quieres hacer una colaboración :(","replies":[{"poster":"FallenDemonX","date":"2016-06-12T05:09:14.815+0000","up_votes":1,"down_votes":0,"body":"Que tienes en mente?","replies":[{"poster":"SteamGameplay","date":"2016-06-12T06:16:33.013+0000","up_votes":1,"down_votes":0,"body":"Un campeon duo, ¿que te parece?","replies":[{"poster":"FallenDemonX","date":"2016-06-14T00:12:55.682+0000","up_votes":1,"down_votes":0,"body":"Hola\n\nDuo eh? hmm interesante. Un tranformista seria lo mas facil, pero ya esta gastado. \n\nAhora que me acuerdo...\n\nhttp://forums.las.leagueoflegends.com/board/showthread.php?t=168248 (Ignora los escalados, era mas joven...)\n\nDigo, por poner un ejemplo. De seguro podemos sacar algo nuevo y mas \"de ambos\"","replies":[{"poster":"SteamGameplay","date":"2016-06-15T00:13:01.865+0000","up_votes":1,"down_votes":0,"body":"te apetece dejarme algo para contactarnos facilmente? tengo algo mas original y que podriamos sacarle provecho ambos","replies":[{"poster":"FallenDemonX","date":"2016-06-15T21:53:03.621+0000","up_votes":1,"down_votes":0,"body":"https://www.facebook.com/nahuel.vazquez.311 \n\nhttp://sonicrainboom706.deviantart.com/","replies":[]}]}]}]}]}]}]}]},{"poster":"SteamGameplay","date":"2016-06-11T21:36:47.766+0000","up_votes":1,"down_votes":0,"body":"H","replies":[]}]}]} |
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{
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[{"questionTitle":"____ Termin wurde von vierzehn auf fünfzehn Uhr verschoben. ","answers":["Der","Die","Das"],"correctAnswer":0},{"questionTitle":"____ Bilanz der Regierung Sarkozy ist nicht gerade hervorragend. ","answers":["Der","Die","Das"],"correctAnswer":1},{"questionTitle":"____ Thema der sprachwissenschaftlichen Tagung war 'das System der Ableitungen mit Suffixen'. ","answers":["Der","Die","Das"],"correctAnswer":2},{"questionTitle":"____ Doktorand hat sein Recht auf ein zusätzliches Jahr für die Abgabe seiner Doktorarbeit geltend gemacht. ","answers":["Der","Die","Das"],"correctAnswer":0},{"questionTitle":"____ Bandit hat einen beachtlichen Schatz zusammengestohlen. ","answers":["Der","Die","Das"],"correctAnswer":0},{"questionTitle":"____ Struktur des Gebäudes ist erdbebensicher. ","answers":["Der","Die","Das"],"correctAnswer":1},{"questionTitle":"____ Überbleibsel des römischen Bades ist in Trier noch zu besichtigen. ","answers":["Der","Die","Das"],"correctAnswer":2},{"questionTitle":"____ Weiterbildung spielt bei Lehrern eine entscheidende Rolle. ","answers":["Der","Die","Das"],"correctAnswer":1},{"questionTitle":"____ Häftling muß noch zwei Jahre im Knast bleiben. ","answers":["Der","Die","Das"],"correctAnswer":0},{"questionTitle":"____ Schicksal der entführten Journalisten ist unbekannt.","answers":["Der","Die","Das"],"correctAnswer":2}] |
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{"poster":"iTzYaBoyJohnCena","date":"2016-09-19T16:42:35.048+0000","title":"Black screen??","subforum":"[ARCHIVED] Help & Support","up_votes":1,"down_votes":0,"body":"At the end of the game I want to check my damage and stats. But it goes black screen??? Why is this??","replies":[{"poster":"Targons Blade","date":"2016-09-19T21:07:35.601+0000","up_votes":1,"down_votes":0,"body":"If your client has a hard time reaching the servers, it could prevent you from reaching the post-game lobby and stats. If you're still seeing this happening, I recommend checking out our [connection guide](https://support.riotgames.com/hc/en-us/articles/201752664-Troubleshooting-Connection-Issues), which will ensure your local network settings are compatible with League.\n\nLet me know if this issue persists.","replies":[]}]} |
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{"poster":"Its Yuu and Mi","date":"2014-11-02T08:11:54.816+0000","title":"Why Did You Fall From Plat Promos to Gold 2, BFNA?","subforum":"[ARCHIVED] General Discussion","up_votes":20,"down_votes":3,"body":"You see, I average 1 AFK loss per day, in Ranked. I have for over a month. I literally cannot get one day without it, unless it's 2 the next day. Yesterday I lost 2 games to AFKs and had an intentional feeder in another, today I've already lost one.\r\n\r\nOh and you think because 4 others on my team and 5 on the enemy that i'll get some on them right? Ahah, no, stupidly rare.\r\n\r\nI'm literally not kidding when I mean, over a month, average one a day. It's amazing I even got to my Plat Promos in the first place.\r\n\r\nBut no, now I'm Gold 2, have to work my ass back up to Gold 1.\r\n\r\nIs this a rant thread?\r\n\r\nSorta, but getting somewhere.\r\n\r\nSee, people say all the time, \"Oh it must not be their fault, they shouldn't be punished.\" And you know what? I just don't give a shit. I don't care if it's not your fault, if you DC'ing cost others you should be punished, with the exception of a bugsplat. IDGAF if your service provider shafted you.\r\n\r\nAnd yes, if I got randomly dc'd for longer than 3 minutes in a game due to my ISP, I'd like to be punished too-- even if it's just one day of no Ranked play.\r\n\r\nSee Lyte keeps saying there will be this new system making it harder to DC in Ranked. And you know what? I've been iistening to that for a lonnnngg time now.\r\n\r\nBut I'm going to be denied my Platinum Season Rewards I should have rightfully earned because of this shit. I've suffered HUNDREDS of losses in Ranked to AFKs. I've won a small, small, small % of that to AFKs on the enemy team.\r\n\r\nAnyone saying 4v5's are winnable is delusional; they are in the most rare of circumstances. You have to be heavily ahead, and win by the 35 minute mark.\r\n\r\nI've invested over 2000$ into League (back when I had money), I've played over 6000 games in 2 years, and I've been on GD almost constantly, day and night, for a good year or so. I'm heavily invested into this game.\r\n\r\nThis is what will break me and make me leave. If this is not fixed by next Season, early next Season, I will be gone.\r\n\r\nThis is shit terrible. I hate that I'm not going to get Platinum rewards because of this crap. \"Oh but you can always play better!\" Sure, I can learn how to play at a D3+ level, that will be significant improvement. When duo'ing up I repeatedly held my own, if not beat out, Plat 3s and better, and even at times Plat 2s, and up to D5s.\r\n\r\nYet, I can't even just get Plat 5, because AFK's/Disconnects are so rampant. \r\n\r\nI don't care if you never DC in this game, and suddenly you do; if it costs us you should be punished. I would expect the same for myself, I am not a hypocrite.\r\n\r\nThis is ruining the game, and I hate it.\r\n\r\nI'll give myself maybe 4 months, and that's generous. If I still find myself averaging a loss a day to DC's, I'm gone. This is stupid.","replies":[]} |
{"poster":"darceeplays","date":"2016-04-30T18:05:28.626+0000","title":"ADC[Gold] sucht duo q Partner/in","subforum":"Clans & Teams","up_votes":1,"down_votes":0,"body":"hallo, suche einen duo q partner/in \r\n\r\nbin derzeit gold 5\r\n\r\n21 Jahre alt\r\n\r\nspiele hauptsächlich adc :\r\n\r\n{{champion:202}} {{champion:236}} {{champion:96}} {{champion:21}} {{champion:67}} \r\n\r\nkann aber auch in der mitte bzw top spielen.\r\n\r\nEigener TS server vorhanden. \r\n\r\nbei Interesse einfach adden","replies":[]} |
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5614, "text": "\u06c1\u0645 \u0646\u06d2 \u0622\u067e \u067e\u0631 \u0642\u0631\u0622\u0646 \u062a\u062f\u0631\u06cc\u062c\u0627 \u0646\u0627\u0632\u0644 \u06a9\u06cc\u0627 \u06c1\u06d2"}, {"id": 678973, "identifier": "ur.jawadi", "surah_number": 76, "surah_ar_name": "\u0633\u0648\u0631\u0629 \u0627\u0644\u0627\u0646\u0633\u0627\u0646", "surah_en_name": "Al-Insaan", "surah_en_name_translation": "Man", "revelation_type": "Medinan", "juz": 29, "manzil": 7, "page": 579, "ruku": 515, "hizb_quarter": 232, "sajda": false, "sajda_id": 0, "sajda_obligatory": false, "sajda_recommended": false, "language": "ur", "name": "\u0639\u0644\u0627\u0645\u06c1 \u062c\u0648\u0627\u062f\u06cc", "transelator_en_name": "Syed Zeeshan Haider Jawadi", "format": "text", "type": "translation", "ayah_number": 5615, "text": "\u0644\u06c1\u0630\u0627 \u0622\u067e \u062d\u06a9\u0645 \u0627\u064e \u062e\u062f\u0627 \u06a9\u06cc \u062e\u0627\u0637\u0631 \u0635\u0628\u0631 \u06a9\u0631\u06cc\u06ba \u0627\u0648\u0631 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{"_id":"A46281","titles":["A discourse of natural bathes, and mineral waters wherein, the original of fountains in general is declared, the nature and difference of minerals with examples of particular bathes, the generation of minerals in the earth, from whence both the actual heat of bathes, and their virtues proceed, by what means mineral waters are to be discover'd, and lastly, of the nature and uses of bathes, but especially of our bathes at Bathe, in Someerset-shire / by Edw. Jorden, Doctor in Physick."],"author":["Jorden, Edward, 1569-1632.","Guidott, Thomas, fl. 1698. Appendix concerning Bathe."],"place":"Imprinted at London :","date":"1669.","publisher":"and are to be sold by Thomas Salmon, bookseller in Bathe,","notes":["Errata: [1] p. at end.","\"An appendix concerning Bathe\" has special t.p. and separate paging.","Reproduction of original in Huntington Library."],"editionDate":"1669","language":"eng","keywords":["Health resorts -- England.","Mineral waters -- Early works to 1800.","Bath (England)"]} |
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sapiens"}},"pub":"17152066"},{"type":"variant","obj":{"id":"ClinVar:RCV000011580","label":"FGD1, 1-BP INS, 945C","variant_type":{"label":["Insertion"]},"pathogenicity":"Pathogenic","coordinates":{"band":"Xp11.21"},"sources":[{"label":"OMIM"}]},"source":{"id":"nlx_151671-1","label":"ClinVar","col":"sequence_alteration","default_taxon":{"id":"NCBITaxon:9606","label":"Homo sapiens"}},"pub":"4146757"},{"type":"variant","obj":{"id":"dbSNP:137853267","label":"NM_004463.2(FGD1):c.1396A>G (p.Met466Val)","variant_type":{"label":["Single nucleotide variant"]},"pathogenicity":"Pathogenic","coordinates":{"band":"Xp11.22"},"sources":[{"label":"OMIM"}]},"source":{"id":"nlx_151671-1","label":"ClinVar","col":"sequence_alteration","default_taxon":{"id":"NCBITaxon:9606","label":"Homo sapiens"}},"pub":"17847065"},{"type":"variant","obj":{"id":"dbSNP:137853267","label":"NM_004463.2(FGD1):c.1396A>G (p.Met466Val)","variant_type":{"label":["Single nucleotide 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J. Hum. Genet.","day":20,"month":11,"year":2011,"meshHeadings":["Dwarfism","Face","Genetic Diseases, X-Linked","Genitalia, Male","Guanine Nucleotide Exchange Factors","Hand Deformities, Congenital","Heart Defects, Congenital","Humans","Mutation"],"hasAbstract":false,"score":0,"snippets":[],"abstract":null,"affiliation":[]},{"pmid":"17152066","pmcid":null,"title":"Unusually severe expression of craniofacial features in Aarskog-Scott syndrome due to a novel truncating mutation of the FGD1 gene.","authors":["Orrico A","Galli L","Obregon MG","de Castro Perez MF","Falciani M","Sorrentino V"],"grantIds":[],"grantAgencies":[],"retractions":[],"journal":"American journal of medical genetics. Part A","journalShort":"Am. J. Med. Genet. A","day":1,"month":1,"year":2007,"meshHeadings":["Adolescent","Child","Craniofacial Abnormalities","Guanine Nucleotide Exchange Factors","Humans","Magnetic Resonance Imaging","Male","Mutation","Pedigree","Siblings","Syndrome","Urogenital Abnormalities"],"hasAbstract":true,"score":0,"snippets":[],"abstract":"Aarskog-Scott syndrome (AAS) is a rare, clinically and genetically heterogeneous condition characterized by facial dysmorphic features, short stature, brachydactyly, and genital anomalies. The X-linked form is caused by mutations of the FGD1 gene. Although clinical manifestations and diagnostic criteria are well established, diagnosis is not simple, as the spectrum of phenotypical features may be extremely variable. Here, we report on the clinical and genetic characterization of a family in which molecular analyses revealed the inheritance of a novel truncating mutation of the FDG1 gene (c.945insC) in two affected brothers, with one of them displaying unusually severe craniofacial abnormalities. This previously unreported combination of anomalies might be due to the occurrence of two distinct disorders (AAS and hemifacial microsomia) or may represent an extension of the AAS phenotypic spectrum. Our findings highlight the phenotypic heterogeneity of AAS, supporting the opinion that the FGD1 mutations result in a broad spectrum of severity and, in some cases, may express a clinical appearance very different than typically described.","affiliation":[]},{"pmid":"16688726","pmcid":null,"title":"Neurobehavioral disorders in patients with Aarskog-Scott syndrome affected by novel FGD1 mutations.","authors":["Kaname T","Yanagi K","Okamoto N","Naritomi K"],"grantIds":[],"grantAgencies":[],"retractions":[],"journal":"American journal of medical genetics. Part A","journalShort":"Am. J. Med. Genet. A","day":15,"month":6,"year":2006,"meshHeadings":["Abnormalities, Multiple","Adolescent","Amino Acid Substitution","Child Behavior Disorders","Child, Preschool","Guanine Nucleotide Exchange Factors","Humans","Leucine","Male","Protein Structure, Tertiary","Syndrome"],"hasAbstract":false,"score":0,"snippets":[],"abstract":null,"affiliation":[]},{"pmid":"20082460","pmcid":null,"title":"Aarskog-Scott syndrome: clinical update and report of nine novel mutations of the FGD1 gene.","authors":["Orrico A","Galli L","Faivre L","Clayton-Smith J","Azzarello-Burri SM","Hertz JM","Jacquemont S","Taurisano R","Arroyo Carrera I","Tarantino E","Devriendt K","Melis D","Thelle T","Meinhardt U","Sorrentino V"],"grantIds":[],"grantAgencies":[],"retractions":[],"journal":"American journal of medical genetics. Part A","journalShort":"Am. J. Med. Genet. A","day":1,"month":2,"year":2010,"meshHeadings":["Abnormalities, Multiple","Amino Acid Motifs","Bone and Bones","Cohort Studies","DNA Mutational Analysis","Europe","Genitalia, Male","Germ-Line Mutation","Guanine Nucleotide Exchange Factors","Humans","Intellectual Disability","Male","Mutation","Phenotype","Syndrome"],"hasAbstract":true,"score":0,"snippets":[],"abstract":"Mutations in the FGD1 gene have been shown to cause Aarskog-Scott syndrome (AAS), or facio-digito-genital dysplasia (OMIM#305400), an X-linked disorder characterized by distinctive genital and skeletal developmental abnormalities with a broad spectrum of clinical phenotypes. To date, 20 distinct mutations have been reported, but little phenotypic data are available on patients with molecularly confirmed AAS. In the present study, we report on our experience of screening for mutations in the FGD1 gene in a cohort of 60 European patients with a clinically suspected diagnosis of AAS. We identified nine novel mutations in 11 patients (detection rate of 18.33%), including three missense mutations (p.R402Q; p.S558W; p.K748E), four truncating mutations (p.Y530X; p.R656X; c.806delC; c.1620delC), one in-frame deletion (c.2020_2022delGAG) and the first reported splice site mutation (c.1935+3A>C). A recurrent mutation (p.R656X) was detected in three independent families. We did not find any evidence for phenotype-genotype correlations between type and position of mutations and clinical features. In addition to the well-established phenotypic features of AAS, other clinical features are also reported and discussed.","affiliation":[]},{"pmid":"7954831","pmcid":null,"title":"Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor.","authors":["Pasteris NG","Cadle A","Logie LJ","Porteous ME","Schwartz CE","Stevenson RE","Glover TW","Wilroy RS","Gorski JL"],"grantIds":["NS-30771","RR-00042"],"grantAgencies":["NINDS NIH HHS","NCRR NIH HHS"],"retractions":[],"journal":"Cell","journalShort":"Cell","day":18,"month":11,"year":1994,"meshHeadings":["Abnormalities, Multiple","Adult","Amino Acid Sequence","Base Sequence","Cell Line","Chromosome Mapping","Chromosomes, Artificial, Yeast","Cloning, Molecular","DNA Mutational Analysis","DNA, Complementary","Face","Fetus","Guanine Nucleotide Exchange Factors","Humans","Hybrid Cells","Molecular Sequence Data","Muscles","Oligodeoxyribonucleotides","Open Reading Frames","Protein Biosynthesis","Proteins","Sequence Homology, Amino Acid","Translocation, Genetic","Urogenital Abnormalities","X Chromosome"],"hasAbstract":true,"score":0,"snippets":[],"abstract":"Faciogenital dysplasia (FGDY), also known as Aarskog-Scott syndrome, is an X-linked developmental disorder characterized by disproportionately short stature and by facial, skeletal, and urogenital anomalies. Molecular genetic analyses mapped FGDY to chromosome Xp11.21. To clone this gene, YAC clones spanning an FGDY-specific translocation breakpoint were isolated. An isolated cDNA, FGD1, is disrupted by the breakpoint, and FGD1 mutations cosegregate with the disease. FGD1 codes for a 961 amino acid protein that has strong homology to Rho/Rac guanine nucleotide exchange factors (GEFs), contains a cysteine-rich zinc finger-like region, and, like the RasGEF mSos, contains two potential SH3-binding sites. These results provide compelling evidence that FGD1 is responsible for FGDY and suggest that FGD1 is a Rho/RacGEF involved in mammalian development.","affiliation":[]},{"pmid":"16353258","pmcid":null,"title":"Clinical variation of Aarskog syndrome in a large family with 2189delA in the FGD1 gene.","authors":["Shalev SA","Chervinski E","Weiner E","Mazor G","Friez MJ","Schwartz CE"],"grantIds":[],"grantAgencies":[],"retractions":[],"journal":"American journal of medical genetics. Part A","journalShort":"Am. J. Med. Genet. A","day":15,"month":1,"year":2006,"meshHeadings":["Abnormalities, Multiple","Cognition Disorders","Consanguinity","DNA Mutational Analysis","Facial Bones","Family Health","Female","Fetal Diseases","Genitalia, Male","Guanine Nucleotide Exchange Factors","Hand Deformities","Heterozygote","Humans","Hypertelorism","Male","Pedigree","Phenotype","Pregnancy","Prenatal Diagnosis","Proteins","Sequence Deletion","Sex Factors","Syndrome"],"hasAbstract":true,"score":0,"snippets":[],"abstract":"The clinical diagnosis of ASS (Aarskog-Scott syndrome or Faciogenital Dysplasia) was made in seven individuals belonging to a large Arabic family, which was supported by molecular studies revealing a 2189delA mutation in exon 15 of the FDG1 gene. The affected individuals in this family demonstrated clinical variability particularly in their cognitive skills, raising the question whether other genetic factors might be involved in the phenotypic evolution of ASS.","affiliation":[]},{"pmid":"15809997","pmcid":null,"title":"Attention-deficit/hyperactivity disorder (ADHD) and variable clinical expression of Aarskog-Scott syndrome due to a novel FGD1 gene mutation (R408Q).","authors":["Orrico A","Galli L","Buoni S","Hayek G","Luchetti A","Lorenzini S","Zappella M","Pomponi MG","Sorrentino V"],"grantIds":[],"grantAgencies":[],"retractions":[],"journal":"American journal of medical genetics. Part A","journalShort":"Am. J. Med. Genet. A","day":15,"month":5,"year":2005,"meshHeadings":["Abnormalities, Multiple","Adolescent","Attention Deficit Disorder with Hyperactivity","Base Sequence","DNA","DNA Mutational Analysis","Face","Fingers","Growth Disorders","Guanine Nucleotide Exchange Factors","Humans","Male","Mutation, Missense","Proteins","Syndrome","Urogenital Abnormalities"],"hasAbstract":true,"score":0,"snippets":[],"abstract":"Mutations of the FGD1 gene are responsible for a significant proportion of patients with Aarskog-Scott syndrome (AAS), an X-linked disorder characterized by short stature, brachydactyly, urogenital abnormalities, and a typical dysmorphic facial appearance. Although mental retardation does not occur significantly in AAS, this condition has been described associated with various degrees of mental impairment and/or behavioral disorders in some patients. In particular, attention deficit hyperactivity disorder (ADHD) is reported as a common characteristic of AAS. However, AAS/ADHD reported patients have been only clinically described, and diagnosis never has been confirmed on molecular basis. We present here a unique case of a 16-years-old patient presenting with ADHD, lower intelligence quotient, and dysmorphic features. Although the clinical features were not completely typical of AAS, genetic analysis demonstrated a novel FGD1 missense mutation (R408Q). The case we report confirms the highly variable expressivity of AAS and first documents that the FGD1 gene may play a role in ADHD susceptibility. We suggest that FGD1 analysis may be adequate in ADHD patients who exhibit dysmorphic features suggestive of AAS, also in the absence of the full phenotypical spectrum.","affiliation":[]},{"pmid":"14560308","pmcid":null,"title":"Phenotypic and molecular characterisation of the Aarskog-Scott syndrome: a survey of the clinical variability in light of FGD1 mutation analysis in 46 patients.","authors":["Orrico A","Galli L","Cavaliere ML","Garavelli L","Fryns JP","Crushell E","Rinaldi MM","Medeira A","Sorrentino V"],"grantIds":[],"grantAgencies":[],"retractions":[],"journal":"European journal of human genetics : EJHG","journalShort":"Eur. J. Hum. Genet.","day":5,"month":1,"year":2004,"meshHeadings":["Adolescent","Adult","Craniofacial Abnormalities","DNA Mutational Analysis","Genetic Heterogeneity","Guanine Nucleotide Exchange Factors","Humans","Male","Mutation","Phenotype","Polymorphism, Single-Stranded Conformational","Proteins","Syndrome","Urogenital Abnormalities"],"hasAbstract":true,"score":0,"snippets":[],"abstract":"Faciogenital dysplasia or Aarskog-Scott syndrome (AAS) is a genetically heterogeneous developmental disorder. The X-linked form of AAS has been ascribed to mutations in the FGD1 gene. However, although AAS may be considered as a relatively frequent clinical diagnosis, mutations have been established in few patients. Genetic heterogeneity and the clinical overlap with a number of other syndromes might explain this discrepancy. In this study, we have conducted a single-strand conformation polymorphism (SSCP) analysis of the entire coding region of FGD1 in 46 AAS patients and identified eight novel mutations, including one insertion, four deletions and three missense mutations (19.56% detection rate). One mutation (528insC) was found in two independent families. The mutations are scattered all along the coding sequence. Phenotypically, all affected males present with the characteristic AAS phenotype. FGD1 mutations were not associated with severe mental retardation. However, neuropsychiatric disorders, mainly behavioural and learning problems in childhood, were observed in five out of 12 mutated individuals. The current study provides further evidence that mutations of FGD1 may cause AAS and expands the spectrum of disease-causing mutations. The importance of considering the neuropsychological phenotype of AAS patients is discussed.","affiliation":[]},{"pmid":"10930571","pmcid":null,"title":"A mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome).","authors":["Orrico A","Galli L","Falciani M","Bracci M","Cavaliere ML","Rinaldi MM","Musacchio A","Sorrentino V"],"grantIds":[],"grantAgencies":[],"retractions":[],"journal":"FEBS letters","journalShort":"FEBS Lett.","day":4,"month":8,"year":2000,"meshHeadings":["Abnormalities, Multiple","Amino Acid Sequence","Amino Acid Substitution","Binding Sites","Blood Proteins","Child, Preschool","Conserved Sequence","DNA Mutational Analysis","Exons","Female","Genetic Heterogeneity","Genetic Linkage","Guanine Nucleotide Exchange Factors","Humans","Italy","Male","Molecular Sequence Data","Mutation","Pedigree","Phenotype","Phosphoproteins","Polymorphism, Single-Stranded Conformational","Protein Structure, Tertiary","Proteins","Sequence Alignment","Syndrome","X Chromosome"],"hasAbstract":true,"score":0,"snippets":[],"abstract":"Aarskog-Scott Syndrome (AAS) is an X-linked disorder characterised by short stature and multiple facial, limb and genital abnormalities. A gene, FGD1, altered in a patient with AAS phenotype, has been identified and found to encode a protein with homology to Rho/Rac guanine nucleotide exchange factors (Rho/Rac GEF). However, since this original report on identification of a mutated FGD1 gene in an AAS patient, no additional mutations in the FGD1 gene have been described. We analysed 13 independent patients with clinical diagnosis of AAS. One patient presented a mutation that results in a nucleotide change in exon 10 of the FGD1 gene (G2559>A) substituting a Gln for Arg in position 610. The mutation was found to segregate with the AAS phenotype in affected males and carrier females in the family of this patient. Interestingly, Arg-610 is located within one of the two pleckstrin homology (PH) domains of the FGD1 gene and it corresponds to a highly conserved residue which has been involved in InsP binding in PH domains of other proteins. The same residue is often mutated in the Bruton's tyrosine kinase (Btk) gene in patients with an X-linked agammaglobulinemia. The Arg610Gln mutation represents the first case of a mutation in the PH domain of the FGD1 gene and additional evidence that mutations in PH domains can be associated to human diseases.","affiliation":[]},{"pmid":"11093277","pmcid":null,"title":"Two novel mutations confirm FGD1 is responsible for the Aarskog syndrome.","authors":["Schwartz CE","Gillessen-Kaesbach G","May M","Cappa M","Gorski J","Steindl K","Neri G"],"grantIds":["HD26202"],"grantAgencies":["NICHD NIH HHS"],"retractions":[],"journal":"European journal of human genetics : EJHG","journalShort":"Eur. J. Hum. Genet.","day":1,"month":11,"year":2000,"meshHeadings":["Abnormalities, Multiple","Amino Acid Sequence","Amino Acid Substitution","Base Sequence","DNA","DNA Mutational Analysis","Facial Bones","Family Health","Female","Guanine Nucleotide Exchange Factors","Humans","Male","Mutation","Pedigree","Point Mutation","Polymorphism, Single-Stranded Conformational","Proteins","Syndrome","Urogenital Abnormalities","X Chromosome"],"hasAbstract":true,"score":0,"snippets":[],"abstract":"The Aarskog syndrome or facio-genital dysplasia (FGDY, MIM No. 305400) is an X-linked condition characterized by short stature, macrocephaly, facial, genital and skeletal anomalies. It is caused by mutation of the FGD1 gene mapped to the Xp11.21 region. To date, only one point mutation has been reported in an affected family, consisting of the insertion of an additional guanine residue at nucleotide 2122 of exon 7, which causes premature translational termination. We now report the finding of two novel FGD1 mutations, a missense mutation in a family of Italian origin and a deletion of 3 exons in a sporadic case from Germany. These mutations confirm the role of FGD1 as the gene responsible for the Aarskog syndrome.","affiliation":[]},{"pmid":"17847065","pmcid":null,"title":"Unilateral focal polymicrogyria in a patient with classical Aarskog-Scott syndrome due to a novel missense mutation in an evolutionary conserved RhoGEF domain of the faciogenital dysplasia gene FGD1.","authors":["Bottani A","Orrico A","Galli L","Karam O","Haenggeli CA","Ferey S","Conrad B"],"grantIds":[],"grantAgencies":[],"retractions":[],"journal":"American journal of medical genetics. Part A","journalShort":"Am. J. Med. Genet. A","day":1,"month":10,"year":2007,"meshHeadings":["Amino Acid Sequence","Animals","Biological Evolution","Face","Genetic Diseases, X-Linked","Genitalia","Guanine Nucleotide Exchange Factors","Humans","Molecular Sequence Data","Mutation, Missense","Rho Guanine Nucleotide Exchange Factors","Sequence Homology, Amino Acid","Syndrome"],"hasAbstract":true,"score":0,"snippets":[],"abstract":"Faciogenital dysplasia or Aarskog-Scott syndrome (AAS) is an X-linked disorder characterized by craniofacial, skeletal, and urogenital malformations and short stature. Mutations in the only known causative gene FGD1 are found in about one-fifth of the cases with the clinical diagnosis of AAS. FGD1 is a guanine nucleotide exchange factor (GEF) that specifically activates the Rho GTPase Cdc42 via its RhoGEF domain. The Cdc42 pathway is involved in skeletal formation and multiple aspects of neuronal development. We describe a boy with typical AAS and, in addition, unilateral focal polymicrogyria (PMG), a feature hitherto unreported in AAS. Sequencing of the FGD1 gene in the index case and his mother revealed the presence of a novel mutation (1396A>G; M466V), located in the evolutionary conserved alpha-helix 4 of the RhoGEF domain. M466V was not found in healthy family members, in >300 healthy controls and AAS patients, and has not been reported in the literature or mutation databases to date, indicating that this novel missense mutation causes AAS, and possibly PMG. Brain cortex malformations such as PMG could be initiated by mutations in the evolutionary conserved RhoGEF domain of FGD1, by perturbing the signaling via Rho GTPases such as Cdc42 known to cause brain malformation.","affiliation":[]},{"pmid":"4146757","pmcid":null,"title":"The facial-digital-genital (Aarskog) syndrome.","authors":["Sugarman GI","Rimoin DL","Lachman RS"],"grantIds":[],"grantAgencies":[],"retractions":[],"journal":"American journal of diseases of children (1960)","journalShort":"Am. J. Dis. 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