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95369245
[ { "id": "1", "type": "title", "text": [ "IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenase." ], "offsets": [ [ 0, 114 ] ] }, { "id": "2", "type": "abstract", "text": [ "Act...
[ { "id": "3", "type": "other_name", "text": [ "IL-2 gene expression" ], "offsets": [ [ 0, 20 ] ], "normalized": [] }, { "id": "4", "type": "DNA_domain_or_region", "text": [ "IL-2 gene" ], "offsets": [ [ 0, ...
[]
[]
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43
95333264
[ { "id": "44", "type": "title", "text": [ "The peri-kappa B site mediates human immunodeficiency virus type 2 enhancer activation in monocytes but not in T cells." ], "offsets": [ [ 0, 119 ] ] }, { "id": "45", "type": "abstract", "text": [ ...
[ { "id": "46", "type": "DNA_domain_or_region", "text": [ "peri-kappa B site" ], "offsets": [ [ 4, 21 ] ], "normalized": [] }, { "id": "47", "type": "other_name", "text": [ "human immunodeficiency virus type 2 enhancer activation" ...
[]
[]
[]
118
95343554
[ { "id": "119", "type": "title", "text": [ "E1A gene expression induces susceptibility to killing by NK cells following immortalization but not adenovirus infection of human cells." ], "offsets": [ [ 0, 136 ] ] }, { "id": "120", "type": "abstract"...
[ { "id": "121", "type": "other_name", "text": [ "E1A gene expression" ], "offsets": [ [ 0, 19 ] ], "normalized": [] }, { "id": "122", "type": "DNA_domain_or_region", "text": [ "E1A gene" ], "offsets": [ [ 0, ...
[]
[]
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154
95347379
[ { "id": "155", "type": "title", "text": [ "Distinct signaling properties identify functionally different CD4 epitopes." ], "offsets": [ [ 0, 75 ] ] }, { "id": "156", "type": "abstract", "text": [ "The CD4 coreceptor interacts with non-p...
[ { "id": "157", "type": "protein_family_or_group", "text": [ "CD4 epitopes" ], "offsets": [ [ 62, 74 ] ], "normalized": [] }, { "id": "158", "type": "protein_molecule", "text": [ "CD4 coreceptor" ], "offsets": [ [ ...
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[]
[]
196
95280913
[ { "id": "197", "type": "title", "text": [ "Ligand-dependent repression of the erythroid transcription factor GATA-1 by the estrogen receptor." ], "offsets": [ [ 0, 98 ] ] }, { "id": "198", "type": "abstract", "text": [ "High-dose estrog...
[ { "id": "199", "type": "other_name", "text": [ "Ligand-dependent repression" ], "offsets": [ [ 0, 27 ] ], "normalized": [] }, { "id": "200", "type": "protein_family_or_group", "text": [ "erythroid transcription factor" ], "o...
[]
[]
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257
95256242
[ { "id": "258", "type": "title", "text": [ "Mouse interleukin-2 receptor alpha gene expression. Interleukin-1 and interleukin-2 control transcription via distinct cis-acting elements." ], "offsets": [ [ 0, 139 ] ] }, { "id": "259", "type": "abstra...
[ { "id": "260", "type": "other_name", "text": [ "Mouse interleukin-2 receptor alpha gene expression" ], "offsets": [ [ 0, 50 ] ], "normalized": [] }, { "id": "261", "type": "DNA_domain_or_region", "text": [ "Mouse interleukin-2 recep...
[]
[]
[]
318
95338146
[ { "id": "319", "type": "title", "text": [ "Hematopoietic lineage commitment: role of transcription factors." ], "offsets": [ [ 0, 64 ] ] }, { "id": "320", "type": "abstract", "text": [ "This review focuses on the roles of transcription ...
[ { "id": "321", "type": "other_name", "text": [ "Hematopoietic lineage commitment" ], "offsets": [ [ 0, 32 ] ], "normalized": [] }, { "id": "322", "type": "cell_type", "text": [ "Hematopoietic lineage" ], "offsets": [ [...
[]
[]
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342
95266275
[ { "id": "343", "type": "title", "text": [ "Epstein-Barr virus replicative gene transcription during de novo infection of human thymocytes: simultaneous early expression of BZLF-1 and its repressor RAZ." ], "offsets": [ [ 0, 158 ] ] }, { "id": "344", ...
[ { "id": "345", "type": "other_name", "text": [ "Epstein-Barr virus replicative gene transcription" ], "offsets": [ [ 0, 49 ] ], "normalized": [] }, { "id": "346", "type": "virus", "text": [ "Epstein-Barr virus" ], "offsets":...
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399
95236292
[ { "id": "400", "type": "title", "text": [ "Identification and purification of human Stat proteins activated in response to interleukin-2." ], "offsets": [ [ 0, 94 ] ] }, { "id": "401", "type": "abstract", "text": [ "A key cytokine induc...
[ { "id": "402", "type": "protein_family_or_group", "text": [ "human Stat proteins" ], "offsets": [ [ 35, 54 ] ], "normalized": [] }, { "id": "403", "type": "protein_molecule", "text": [ "interleukin-2" ], "offsets": [ [...
[]
[]
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427
95197524
[ { "id": "428", "type": "title", "text": [ "E2F-1 and a cyclin-like DNA repair enzyme, uracil-DNA glycosylase, provide evidence for an autoregulatory mechanism for transcription." ], "offsets": [ [ 0, 134 ] ] }, { "id": "429", "type": "abstract", ...
[ { "id": "430", "type": "protein_molecule", "text": [ "E2F-1" ], "offsets": [ [ 0, 5 ] ], "normalized": [] }, { "id": "431", "type": "protein_family_or_group", "text": [ "cyclin-like DNA repair enzyme" ], "offsets": [ [...
[]
[]
[]
479
95370702
[ { "id": "480", "type": "title", "text": [ "Cellular and molecular mechanisms of IFN-gamma production induced by IL-2 and IL-12 in a human NK cell line." ], "offsets": [ [ 0, 108 ] ] }, { "id": "481", "type": "abstract", "text": [ "Inter...
[ { "id": "482", "type": "(AND other_name other_name)", "text": [ "Cellular and molecular mechanisms" ], "offsets": [ [ 0, 33 ] ], "normalized": [] }, { "id": "483", "type": "", "text": [ "Cellular" ], "offsets": [ [ ...
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[]
[]
583
95349600
[ { "id": "584", "type": "title", "text": [ "A functional T-cell receptor signaling pathway is required for p95vav activity." ], "offsets": [ [ 0, 79 ] ] }, { "id": "585", "type": "abstract", "text": [ "Stimulation of the T-cell antigen r...
[ { "id": "586", "type": "other_name", "text": [ "functional T-cell receptor signaling pathway" ], "offsets": [ [ 2, 46 ] ], "normalized": [] }, { "id": "587", "type": "protein_family_or_group", "text": [ "T-cell receptor" ], ...
[]
[]
[]
669
95329717
[ { "id": "670", "type": "title", "text": [ "Positive and negative regulation of granulocyte-macrophage colony-stimulating factor promoter activity by AML1-related transcription factor, PEBP2." ], "offsets": [ [ 0, 147 ] ] }, { "id": "671", "type":...
[ { "id": "672", "type": "(AND other_name other_name)", "text": [ "Positive and negative regulation" ], "offsets": [ [ 0, 32 ] ], "normalized": [] }, { "id": "673", "type": "", "text": [ "Positive" ], "offsets": [ [ ...
[]
[]
[]
756
96075792
[ { "id": "757", "type": "title", "text": [ "IFN-gamma priming of monocytes enhances LPS-induced TNF production by augmenting both transcription and MRNA stability." ], "offsets": [ [ 0, 119 ] ] }, { "id": "758", "type": "abstract", "text": [ ...
[ { "id": "759", "type": "protein_molecule", "text": [ "IFN-gamma" ], "offsets": [ [ 0, 9 ] ], "normalized": [] }, { "id": "760", "type": "cell_type", "text": [ "monocytes" ], "offsets": [ [ 21, 30 ...
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828
95280917
[ { "id": "829", "type": "title", "text": [ "A Myc-associated zinc finger protein binding site is one of four important functional regions in the CD4 promoter." ], "offsets": [ [ 0, 114 ] ] }, { "id": "830", "type": "abstract", "text": [ ...
[ { "id": "831", "type": "DNA_domain_or_region", "text": [ "Myc-associated zinc finger protein binding site" ], "offsets": [ [ 2, 49 ] ], "normalized": [] }, { "id": "832", "type": "protein_family_or_group", "text": [ "Myc-associated ...
[]
[]
[]
866
95263486
[ { "id": "867", "type": "title", "text": [ "Erythropoietin stimulates transcription of the TAL1/SCL gene and phosphorylation of its protein products." ], "offsets": [ [ 0, 105 ] ] }, { "id": "868", "type": "abstract", "text": [ "Activati...
[ { "id": "869", "type": "protein_molecule", "text": [ "Erythropoietin" ], "offsets": [ [ 0, 14 ] ], "normalized": [] }, { "id": "870", "type": "DNA_domain_or_region", "text": [ "TAL1/SCL gene" ], "offsets": [ [ ...
[]
[]
[]
925
95397944
[ { "id": "926", "type": "title", "text": [ "Nonradioactive quantification of glucocorticoid receptor expression during differentiation of human monocytic cells (U937)." ], "offsets": [ [ 0, 123 ] ] }, { "id": "927", "type": "abstract", "text":...
[ { "id": "928", "type": "other_name", "text": [ "Nonradioactive quantification" ], "offsets": [ [ 0, 29 ] ], "normalized": [] }, { "id": "929", "type": "other_name", "text": [ "glucocorticoid receptor expression" ], "offsets"...
[]
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957
95266282
[ { "id": "958", "type": "title", "text": [ "Induction of Sp1 phosphorylation and NF-kappa B-independent HIV promoter domain activity in T lymphocytes stimulated by okadaic acid." ], "offsets": [ [ 0, 133 ] ] }, { "id": "959", "type": "abstract", ...
[ { "id": "960", "type": "other_name", "text": [ "Sp1 phosphorylation" ], "offsets": [ [ 13, 32 ] ], "normalized": [] }, { "id": "961", "type": "protein_molecule", "text": [ "Sp1" ], "offsets": [ [ 13, 16...
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1035
95236293
[ { "id": "1036", "type": "title", "text": [ "The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15." ], "offsets": [ [ 0, 154 ] ] }, { "id": "1037", ...
[ { "id": "1038", "type": "protein_substructure", "text": [ "shared receptor motifs" ], "offsets": [ [ 12, 34 ] ], "normalized": [] }, { "id": "1039", "type": "protein_family_or_group", "text": [ "common Stat proteins" ], "off...
[]
[]
[]
1080
95184007
[ { "id": "1081", "type": "title", "text": [ "Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation." ], "offsets": [ [ 0, 88 ] ] }, { "id": "1082", "type": "abstract", "text": [ "I kappa B-alpha inhibits...
[ { "id": "1083", "type": "other_name", "text": [ "I kappa B-alpha proteolysis" ], "offsets": [ [ 11, 38 ] ], "normalized": [] }, { "id": "1084", "type": "protein_molecule", "text": [ "I kappa B-alpha" ], "offsets": [ [ ...
[]
[]
[]
1109
95388524
[ { "id": "1110", "type": "title", "text": [ "Regulation of transcription of the human erythropoietin receptor gene by proteins binding to GATA-1 and Sp1 motifs." ], "offsets": [ [ 0, 115 ] ] }, { "id": "1111", "type": "abstract", "text": [ ...
[ { "id": "1112", "type": "other_name", "text": [ "transcription" ], "offsets": [ [ 14, 27 ] ], "normalized": [] }, { "id": "1113", "type": "DNA_domain_or_region", "text": [ "human erythropoietin receptor gene" ], "offsets": [...
[]
[]
[]
1192
95365382
[ { "id": "1193", "type": "title", "text": [ "Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells." ], "offsets": [ [ 0, 165 ] ] }, { "id":...
[ { "id": "1195", "type": "protein_molecule", "text": [ "DR-nm23" ], "offsets": [ [ 18, 25 ] ], "normalized": [] }, { "id": "1196", "type": "DNA_family_or_group", "text": [ "nm23 gene family" ], "offsets": [ [ 64...
[]
[]
[]
1243
96032864
[ { "id": "1244", "type": "title", "text": [ "An interferon-gamma activation sequence mediates the transcriptional regulation of the IgG Fc receptor type IC gene by interferon-gamma." ], "offsets": [ [ 0, 136 ] ] }, { "id": "1245", "type": "abstrac...
[ { "id": "1246", "type": "DNA_domain_or_region", "text": [ "interferon-gamma activation sequence" ], "offsets": [ [ 3, 39 ] ], "normalized": [] }, { "id": "1247", "type": "other_name", "text": [ "transcriptional regulation" ], ...
[]
[]
[]
1310
95327953
[ { "id": "1311", "type": "title", "text": [ "Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I." ], "offsets": [ [ 0, 77 ] ] }, { "id": "1312", "type": "abstract", "text": [ "Human T cell lymphotropic virus I (...
[ { "id": "1313", "type": "other_name", "text": [ "Jak-STAT pathway" ], "offsets": [ [ 25, 41 ] ], "normalized": [] }, { "id": "1314", "type": "protein_family_or_group", "text": [ "Jak" ], "offsets": [ [ 25, ...
[]
[]
[]
1355
95340873
[ { "id": "1356", "type": "title", "text": [ "Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines." ], "offsets": [ [ 0, 172 ] ] }, { ...
[ { "id": "1358", "type": "inorganic", "text": [ "Nitric oxide" ], "offsets": [ [ 0, 12 ] ], "normalized": [] }, { "id": "1359", "type": "other_name", "text": [ "cytokine-induced endothelial activation" ], "offsets": [ [...
[]
[]
[]
1422
95280909
[ { "id": "1423", "type": "title", "text": [ "MIP1 alpha nuclear protein (MNP), a novel transcription factor expressed in hematopoietic cells that is crucial for transcription of the human MIP-1 alpha gene." ], "offsets": [ [ 0, 160 ] ] }, { "id": "142...
[ { "id": "1425", "type": "protein_molecule", "text": [ "MIP1 alpha nuclear protein" ], "offsets": [ [ 0, 26 ] ], "normalized": [] }, { "id": "1426", "type": "protein_molecule", "text": [ "MNP" ], "offsets": [ [ ...
[]
[]
[]
1486
96055286
[ { "id": "1487", "type": "title", "text": [ "The effect of Toremifene on the expression of some genes in human mononuclear cells." ], "offsets": [ [ 0, 84 ] ] }, { "id": "1488", "type": "abstract", "text": [ "Toremifene exerts multiple a...
[ { "id": "1489", "type": "other_organic_compound", "text": [ "Toremifene" ], "offsets": [ [ 14, 24 ] ], "normalized": [] }, { "id": "1490", "type": "cell_type", "text": [ "human mononuclear cells" ], "offsets": [ [ ...
[]
[]
[]
1506
95337737
[ { "id": "1507", "type": "title", "text": [ "The interleukin-5/receptor interaction activates Lyn and Jak2 tyrosine kinases and propagates signals via the Ras-Raf-1-MAP kinase and the Jak-STAT pathways in eosinophils." ], "offsets": [ [ 0, 172 ] ] }, { ...
[ { "id": "1509", "type": "other_name", "text": [ "interleukin-5/receptor interaction" ], "offsets": [ [ 4, 38 ] ], "normalized": [] }, { "id": "1510", "type": "protein_family_or_group", "text": [ "interleukin-5" ], "offsets":...
[]
[]
[]
1553
95266250
[ { "id": "1554", "type": "title", "text": [ "The retinoblastoma gene product negatively regulates transcriptional activation mediated by the human cytomegalovirus IE2 protein." ], "offsets": [ [ 0, 130 ] ] }, { "id": "1555", "type": "abstract", ...
[ { "id": "1556", "type": "protein_molecule", "text": [ "retinoblastoma gene product" ], "offsets": [ [ 4, 31 ] ], "normalized": [] }, { "id": "1557", "type": "protein_N/A", "text": [ "transcriptional activation" ], "offsets":...
[]
[]
[]
1596
96082382
[ { "id": "1597", "type": "title", "text": [ "Expression of the nucleoside diphosphate kinase in human skin cancers: an immunohistochemical study." ], "offsets": [ [ 0, 100 ] ] }, { "id": "1598", "type": "abstract", "text": [ "Expression ...
[ { "id": "1599", "type": "protein_molecule", "text": [ "nucleoside diphosphate kinase" ], "offsets": [ [ 18, 47 ] ], "normalized": [] }, { "id": "1600", "type": "other_name", "text": [ "human skin cancers" ], "offsets": [ ...
[]
[]
[]
1641
95362365
[ { "id": "1642", "type": "title", "text": [ "RB and a novel E2F-1 binding protein in MHC class II deficient B-cell lines and normal IFN-gamma induction of the class IL transactivator CIITA in class II non-inducible RB-defective tumor lines." ], "offsets": [ [ 0, 195 ...
[ { "id": "1644", "type": "protein_molecule", "text": [ "RB" ], "offsets": [ [ 0, 2 ] ], "normalized": [] }, { "id": "1645", "type": "protein_family_or_group", "text": [ "E2F-1 binding protein" ], "offsets": [ [ ...
[]
[]
[]
1703
95365357
[ { "id": "1704", "type": "title", "text": [ "Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes." ], "offsets": [ [ 0, 93 ] ] }, { "id": "1705", "type": "abstract", "text": [ "Interleukin 12 (IL-...
[ { "id": "1706", "type": "protein_molecule", "text": [ "Interleukin 12" ], "offsets": [ [ 0, 14 ] ], "normalized": [] }, { "id": "1707", "type": "other_name", "text": [ "tyrosine phosphorylation" ], "offsets": [ [ ...
[]
[]
[]
1755
96007705
[ { "id": "1756", "type": "title", "text": [ "Temperature-induced down-regulation of the glucocorticoid receptor in peripheral blood mononuclear leucocyte in patients with sepsis or septic shock." ], "offsets": [ [ 0, 149 ] ] }, { "id": "1757", "ty...
[ { "id": "1758", "type": "protein_family_or_group", "text": [ "glucocorticoid receptor" ], "offsets": [ [ 43, 66 ] ], "normalized": [] }, { "id": "1759", "type": "cell_type", "text": [ "peripheral blood mononuclear leucocyte" ], ...
[]
[]
[]
1806
95332324
[ { "id": "1807", "type": "title", "text": [ "Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase." ], "offsets": [ [ 0, 148 ] ] }, { "id": "1808", "typ...
[ { "id": "1809", "type": "other_name", "text": [ "tyrosine phosphorylation" ], "offsets": [ [ 18, 42 ] ], "normalized": [] }, { "id": "1810", "type": "amino_acid_monomer", "text": [ "tyrosine" ], "offsets": [ [ ...
[]
[]
[]
1886
96065933
[ { "id": "1887", "type": "title", "text": [ "Inhibition of dexamethasone binding to human glucocorticoid receptor by New World primate cell extracts." ], "offsets": [ [ 0, 104 ] ] }, { "id": "1888", "type": "abstract", "text": [ "To dete...
[ { "id": "1889", "type": "lipid", "text": [ "dexamethasone" ], "offsets": [ [ 14, 27 ] ], "normalized": [] }, { "id": "1890", "type": "protein_family_or_group", "text": [ "human glucocorticoid receptor" ], "offsets": [ ...
[]
[]
[]
1937
95392577
[ { "id": "1938", "type": "title", "text": [ "Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals." ], "offsets": [ [ 0, 120 ] ] }, { "id": "1939", "type": "abstract", "text": ...
[ { "id": "1940", "type": "DNA_domain_or_region", "text": [ "GATA motif" ], "offsets": [ [ 16, 26 ] ], "normalized": [] }, { "id": "1941", "type": "DNA_domain_or_region", "text": [ "Duffy gene promoter" ], "offsets": [ [...
[]
[]
[]
1971
95287633
[ { "id": "1972", "type": "title", "text": [ "Activation of pp90rsk and early growth response-1 gene expression by pokeweed mitogen in human B cells." ], "offsets": [ [ 0, 103 ] ] }, { "id": "1973", "type": "abstract", "text": [ "The pres...
[ { "id": "1974", "type": "protein_molecule", "text": [ "pp90rsk" ], "offsets": [ [ 14, 21 ] ], "normalized": [] }, { "id": "1975", "type": "other_name", "text": [ "early growth response-1 gene expression" ], "offsets": [ ...
[]
[]
[]
2018
95337734
[ { "id": "2019", "type": "title", "text": [ "A conserved motif in the promoters of several cytokines expressed by human Th2-type lymphocytes." ], "offsets": [ [ 0, 96 ] ] }, { "id": "2020", "type": "abstract", "text": [ "We have recently...
[ { "id": "2021", "type": "DNA_domain_or_region", "text": [ "conserved motif" ], "offsets": [ [ 2, 17 ] ], "normalized": [] }, { "id": "2022", "type": "DNA_family_or_group", "text": [ "promoters" ], "offsets": [ [ ...
[]
[]
[]
2063
95221892
[ { "id": "2064", "type": "title", "text": [ "cDNA cloning of a NGFI-B/nur77-related transcription factor from an apoptotic human T cell line." ], "offsets": [ [ 0, 96 ] ] }, { "id": "2065", "type": "abstract", "text": [ "A human T lympho...
[ { "id": "2066", "type": "other_name", "text": [ "cDNA cloning" ], "offsets": [ [ 0, 12 ] ], "normalized": [] }, { "id": "2067", "type": "DNA_family_or_group", "text": [ "cDNA" ], "offsets": [ [ 0, 4 ...
[]
[]
[]
2088
95202809
[ { "id": "2089", "type": "title", "text": [ "Aspirin inhibits nuclear factor-kappa B mobilization and monocyte adhesion in stimulated human endothelial cells." ], "offsets": [ [ 0, 113 ] ] }, { "id": "2090", "type": "abstract", "text": [ ...
[ { "id": "2091", "type": "other_organic_compound", "text": [ "Aspirin" ], "offsets": [ [ 0, 7 ] ], "normalized": [] }, { "id": "2092", "type": "other_name", "text": [ "nuclear factor-kappa B mobilization" ], "offsets": [ ...
[]
[]
[]
2155
95355456
[ { "id": "2156", "type": "title", "text": [ "Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites." ], "offsets": [ [ 0, 133 ] ] }, { "id": "2157", "type": "abstract",...
[ { "id": "2158", "type": "protein_molecule", "text": [ "NF-kappa B" ], "offsets": [ [ 14, 24 ] ], "normalized": [] }, { "id": "2159", "type": "other_name", "text": [ "phosphatase inhibitors" ], "offsets": [ [ 28...
[]
[]
[]
2218
95365343
[ { "id": "2219", "type": "title", "text": [ "Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity." ], "offsets": [ [ 0, 94 ] ] }, { "id": "2220", "type": "abstract", "text": [ "The 5' flanking re...
[ { "id": "2221", "type": "other_name", "text": [ "Sp1 functions" ], "offsets": [ [ 0, 13 ] ], "normalized": [] }, { "id": "2222", "type": "protein_molecule", "text": [ "Sp1" ], "offsets": [ [ 0, 3 ...
[]
[]
[]
2263
95363078
[ { "id": "2264", "type": "title", "text": [ "Costimulation of human CD4+ T cells with LFA-3 and B7 induce distinct effects on AP-1 and NF-kappa B transcription factors." ], "offsets": [ [ 0, 123 ] ] }, { "id": "2265", "type": "abstract", "text...
[ { "id": "2266", "type": "cell_line", "text": [ "human CD4+ T cells" ], "offsets": [ [ 17, 35 ] ], "normalized": [] }, { "id": "2267", "type": "protein_molecule", "text": [ "LFA-3" ], "offsets": [ [ 41, ...
[]
[]
[]
2341
95336453
[ { "id": "2342", "type": "title", "text": [ "The Ah receptor recognizes DNA binding sites for the B cell transcription factor, BSAP: a possible mechanism for dioxin-mediated alteration of CD19 gene expression in human B lymphocytes." ], "offsets": [ [ 0, 187 ] ...
[ { "id": "2344", "type": "protein_molecule", "text": [ "Ah receptor" ], "offsets": [ [ 4, 15 ] ], "normalized": [] }, { "id": "2345", "type": "DNA_domain_or_region", "text": [ "DNA binding sites" ], "offsets": [ [ ...
[]
[]
[]
2385
95337142
[ { "id": "2386", "type": "title", "text": [ "Inhibitory action of nm23 proteins on induction of erythroid differentiation of human leukemia cells." ], "offsets": [ [ 0, 101 ] ] }, { "id": "2387", "type": "abstract", "text": [ "We recentl...
[ { "id": "2388", "type": "other_name", "text": [ "Inhibitory action" ], "offsets": [ [ 0, 17 ] ], "normalized": [] }, { "id": "2389", "type": "protein_family_or_group", "text": [ "nm23 proteins" ], "offsets": [ [ ...
[]
[]
[]
2471
95355137
[ { "id": "2472", "type": "title", "text": [ "Lipopolysaccharide-induced E-selectin expression requires continuous presence of LPS and is inhibited by bactericidal/permeability-increasing protein." ], "offsets": [ [ 0, 150 ] ] }, { "id": "2473", "t...
[ { "id": "2474", "type": "other_name", "text": [ "Lipopolysaccharide-induced E-selectin expression" ], "offsets": [ [ 0, 48 ] ], "normalized": [] }, { "id": "2475", "type": "lipid", "text": [ "Lipopolysaccharide" ], "offsets"...
[]
[]
[]
2511
95279882
[ { "id": "2512", "type": "title", "text": [ "GM-CSF and IL-2 share common control mechanisms in response to costimulatory signals in T cells." ], "offsets": [ [ 0, 96 ] ] }, { "id": "2513", "type": "abstract", "text": [ "Antigen complexe...
[ { "id": "2514", "type": "protein_molecule", "text": [ "GM-CSF" ], "offsets": [ [ 0, 6 ] ], "normalized": [] }, { "id": "2515", "type": "protein_molecule", "text": [ "IL-2" ], "offsets": [ [ 11, 15 ...
[]
[]
[]
2603
95309632
[ { "id": "2604", "type": "title", "text": [ "Danazol decreases transcription of estrogen receptor gene in human monocytes." ], "offsets": [ [ 0, 77 ] ] }, { "id": "2605", "type": "abstract", "text": [ "1. Administration of danazol for ov...
[ { "id": "2606", "type": "other_organic_compound", "text": [ "Danazol" ], "offsets": [ [ 0, 7 ] ], "normalized": [] }, { "id": "2607", "type": "DNA_domain_or_region", "text": [ "estrogen receptor gene" ], "offsets": [ [...
[]
[]
[]
2634
95221870
[ { "id": "2635", "type": "title", "text": [ "Functional characterization of novel IL-2 transcriptional inhibitors." ], "offsets": [ [ 0, 69 ] ] }, { "id": "2636", "type": "abstract", "text": [ "IL-2-mediated T cell proliferation is a cri...
[ { "id": "2637", "type": "other_name", "text": [ "IL-2 transcriptional inhibitors" ], "offsets": [ [ 37, 68 ] ], "normalized": [] }, { "id": "2638", "type": "protein_molecule", "text": [ "IL-2" ], "offsets": [ [ ...
[]
[]
[]
2690
95221386
[ { "id": "2691", "type": "title", "text": [ "Transcriptional regulation of the vacuolar H(+)-ATPase B2 subunit gene in differentiating THP-1 cells." ], "offsets": [ [ 0, 102 ] ] }, { "id": "2692", "type": "abstract", "text": [ "Monocyte-...
[ { "id": "2693", "type": "other_name", "text": [ "Transcriptional regulation" ], "offsets": [ [ 0, 26 ] ], "normalized": [] }, { "id": "2694", "type": "DNA_domain_or_region", "text": [ "vacuolar H(+)-ATPase B2 subunit gene" ], ...
[]
[]
[]
2745
96089572
[ { "id": "2746", "type": "title", "text": [ "Synergy between signal transduction pathways is obligatory for expression of c-fos in B and T cell lines: implication for c-fos control via surface immunoglobulin and T cell antigen receptors." ], "offsets": [ [ 0, 192 ...
[ { "id": "2748", "type": "other_name", "text": [ "signal transduction pathways" ], "offsets": [ [ 16, 44 ] ], "normalized": [] }, { "id": "2749", "type": "DNA_domain_or_region", "text": [ "c-fos" ], "offsets": [ [ ...
[]
[]
[]
2853
95363089
[ { "id": "2854", "type": "title", "text": [ "Multiple signals are required for function of the human granulocyte-macrophage colony-stimulating factor gene promoter in T cells." ], "offsets": [ [ 0, 130 ] ] }, { "id": "2855", "type": "abstract", ...
[ { "id": "2856", "type": "DNA_domain_or_region", "text": [ "human granulocyte-macrophage colony-stimulating factor gene promoter" ], "offsets": [ [ 50, 118 ] ], "normalized": [] }, { "id": "2857", "type": "protein_molecule", "text": [ ...
[]
[]
[]
2954
95363073
[ { "id": "2955", "type": "title", "text": [ "IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes." ], "offsets": [ [ 0, 156 ] ] }, { "id": "2956", ...
[ { "id": "2957", "type": "other_name", "text": [ "tyrosine phosphorylation" ], "offsets": [ [ 18, 42 ] ], "normalized": [] }, { "id": "2958", "type": "amino_acid_monomer", "text": [ "tyrosine" ], "offsets": [ [ ...
[]
[]
[]
3006
97253017
[ { "id": "3007", "type": "title", "text": [ "Use of new biologic markers in the ovulation induction." ], "offsets": [ [ 0, 55 ] ] }, { "id": "3008", "type": "abstract", "text": [ "Biological markers of ovulation, after a great in the pas...
[ { "id": "3009", "type": "other_name", "text": [ "biologic markers" ], "offsets": [ [ 11, 27 ] ], "normalized": [] }, { "id": "3010", "type": "other_name", "text": [ "ovulation induction" ], "offsets": [ [ 35, ...
[]
[]
[]
3025
95279790
[ { "id": "3026", "type": "title", "text": [ "Abnormal regulation of the IL-2 promoter in lpr CD4-CD8- T lymphocytes results in constitutive expression of a novel nuclear factor of activated T cells-binding factor." ], "offsets": [ [ 0, 168 ] ] }, { "i...
[ { "id": "3028", "type": "DNA_domain_or_region", "text": [ "IL-2 promoter" ], "offsets": [ [ 27, 40 ] ], "normalized": [] }, { "id": "3029", "type": "protein_molecule", "text": [ "IL-2" ], "offsets": [ [ 27, ...
[]
[]
[]
3094
95316714
[ { "id": "3095", "type": "title", "text": [ "Cross-linking of CD30 induces HIV expression in chronically infected T cells." ], "offsets": [ [ 0, 77 ] ] }, { "id": "3096", "type": "abstract", "text": [ "CD30, a member of the tumor necrosi...
[ { "id": "3097", "type": "protein_molecule", "text": [ "CD30" ], "offsets": [ [ 17, 21 ] ], "normalized": [] }, { "id": "3098", "type": "other_name", "text": [ "HIV expression" ], "offsets": [ [ 30, 44 ...
[]
[]
[]
3132
95269137
[ { "id": "3133", "type": "title", "text": [ "Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency." ], "offsets": [ [ 0, 151 ] ] }, { "id": "3134", "...
[ { "id": "3135", "type": "other_name", "text": [ "Human MHC class II gene transcription" ], "offsets": [ [ 0, 37 ] ], "normalized": [] }, { "id": "3136", "type": "DNA_family_or_group", "text": [ "MHC class II gene" ], "offset...
[]
[]
[]
3184
95256455
[ { "id": "3185", "type": "title", "text": [ "Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation [see comments]" ], "offsets": [ [ 0, 179 ] ] },...
[ { "id": "3187", "type": "protein_molecule", "text": [ "P-selectin" ], "offsets": [ [ 22, 32 ] ], "normalized": [] }, { "id": "3188", "type": "protein_molecule", "text": [ "monocyte chemotactic protein-1" ], "offsets": [ ...
[]
[]
[]
3229
95238333
[ { "id": "3230", "type": "title", "text": [ "Functional roles of in vivo footprinted DNA motifs within an alpha-globin enhancer. Erythroid lineage and developmental stage specificities." ], "offsets": [ [ 0, 140 ] ] }, { "id": "3231", "type": "abs...
[ { "id": "3232", "type": "DNA_family_or_group", "text": [ "in vivo footprinted DNA motifs" ], "offsets": [ [ 20, 50 ] ], "normalized": [] }, { "id": "3233", "type": "DNA_domain_or_region", "text": [ "alpha-globin enhancer" ], ...
[]
[]
[]
3289
95221342
[ { "id": "3290", "type": "title", "text": [ "Nitric oxide-stimulated guanine nucleotide exchange on p21ras." ], "offsets": [ [ 0, 62 ] ] }, { "id": "3291", "type": "abstract", "text": [ "The protooncogene p21ras, a monomeric G protein fa...
[ { "id": "3292", "type": "other_name", "text": [ "Nitric oxide-stimulated guanine nucleotide exchange" ], "offsets": [ [ 0, 51 ] ], "normalized": [] }, { "id": "3293", "type": "inorganic", "text": [ "Nitric oxide" ], "offsets...
[]
[]
[]
3337
95394020
[ { "id": "3338", "type": "title", "text": [ "Interleukin-2 promoter activity in Epstein-Barr virus-transformed B lymphocytes is controlled by nuclear factor-chi B." ], "offsets": [ [ 0, 118 ] ] }, { "id": "3339", "type": "abstract", "text": [ ...
[ { "id": "3340", "type": "other_name", "text": [ "Interleukin-2 promoter activity" ], "offsets": [ [ 0, 31 ] ], "normalized": [] }, { "id": "3341", "type": "DNA_domain_or_region", "text": [ "Interleukin-2 promoter" ], "offset...
[]
[]
[]
3423
95363069
[ { "id": "3424", "type": "title", "text": [ "Latent membrane protein-1 induces cyclin D2 expression, pRb hyperphosphorylation, and loss of TGF-beta 1-mediated growth inhibition in EBV-positive B cells." ], "offsets": [ [ 0, 156 ] ] }, { "id": "3425", ...
[ { "id": "3426", "type": "protein_molecule", "text": [ "Latent membrane protein-1" ], "offsets": [ [ 0, 25 ] ], "normalized": [] }, { "id": "3427", "type": "other_name", "text": [ "cyclin D2 expression" ], "offsets": [ ...
[]
[]
[]
3487
95355533
[ { "id": "3488", "type": "title", "text": [ "Does thyroidectomy, radioactive iodine therapy, or antithyroid drug treatment alter reactivity of patients' T cells to epitopes of thyrotropin receptor in autoimmune thyroid diseases?" ], "offsets": [ [ 0, 183 ] ] ...
[ { "id": "3490", "type": "other_name", "text": [ "thyroidectomy" ], "offsets": [ [ 5, 18 ] ], "normalized": [] }, { "id": "3491", "type": "other_name", "text": [ "radioactive iodine therapy" ], "offsets": [ [ 20...
[]
[]
[]
3589
96030053
[ { "id": "3590", "type": "title", "text": [ "Circumvention of tolerance for the nuclear T cell protein TCF-1 by immunization of TCF-1 knock-out mice." ], "offsets": [ [ 0, 104 ] ] }, { "id": "3591", "type": "abstract", "text": [ "Molecul...
[ { "id": "3592", "type": "protein_family_or_group", "text": [ "nuclear T cell protein" ], "offsets": [ [ 35, 57 ] ], "normalized": [] }, { "id": "3593", "type": "protein_molecule", "text": [ "TCF-1" ], "offsets": [ [ ...
[]
[]
[]
3635
95286632
[ { "id": "3636", "type": "title", "text": [ "The transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in Burkitt's lymphoma." ], "offsets": [ [ 0, 109 ] ] }, { "id": "3637", "type": "abstract", "text": [ "We...
[ { "id": "3638", "type": "protein_family_or_group", "text": [ "transcription factor" ], "offsets": [ [ 4, 24 ] ], "normalized": [] }, { "id": "3639", "type": "protein_molecule", "text": [ "Nm23H2" ], "offsets": [ [ ...
[]
[]
[]
3670
95279435
[ { "id": "3671", "type": "title", "text": [ "Identification of two novel regulatory elements within the 5'-untranslated region of the human A gamma-globin gene." ], "offsets": [ [ 0, 115 ] ] }, { "id": "3672", "type": "abstract", "text": [ ...
[ { "id": "3673", "type": "DNA_family_or_group", "text": [ "regulatory elements" ], "offsets": [ [ 28, 47 ] ], "normalized": [] }, { "id": "3674", "type": "DNA_domain_or_region", "text": [ "5'-untranslated region" ], "offsets"...
[]
[]
[]
3721
95257963
[ { "id": "3722", "type": "title", "text": [ "Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation." ], "offsets": [ [ 0, 103 ] ] }, { "id": "3723", "type": "abstract", "text": [ "The euka...
[ { "id": "3724", "type": "protein_domain_or_region", "text": [ "signal response domain" ], "offsets": [ [ 14, 36 ] ], "normalized": [] }, { "id": "3725", "type": "protein_molecule", "text": [ "I kappa B alpha" ], "offsets": [...
[]
[]
[]
3787
95255485
[ { "id": "3788", "type": "title", "text": [ "Growth regulation and cellular changes during differentiation of human prostatic cancer LNCaP cells as induced by T lymphocyte-conditioned medium." ], "offsets": [ [ 0, 146 ] ] }, { "id": "3789", "type"...
[ { "id": "3790", "type": "other_name", "text": [ "Growth regulation" ], "offsets": [ [ 0, 17 ] ], "normalized": [] }, { "id": "3791", "type": "other_name", "text": [ "cellular changes" ], "offsets": [ [ 22, ...
[]
[]
[]
3852
95229576
[ { "id": "3853", "type": "title", "text": [ "Platelet-activating factor stimulates transcription of the heparin-binding epidermal growth factor-like growth factor in monocytes. Correlation with an increased kappa B binding activity." ], "offsets": [ [ 0, 187 ] ...
[ { "id": "3855", "type": "protein_family_or_group", "text": [ "Platelet-activating factor" ], "offsets": [ [ 0, 26 ] ], "normalized": [] }, { "id": "3856", "type": "protein_molecule", "text": [ "heparin-binding epidermal growth facto...
[]
[]
[]
3903
95197681
[ { "id": "3904", "type": "title", "text": [ "Mapping of the interaction site of the defective transcription factor in the class II major histocompatibility complex mutant cell line clone-13 to the divergent X2-box." ], "offsets": [ [ 0, 169 ] ] }, { "...
[ { "id": "3906", "type": "protein_domain_or_region", "text": [ "interaction site" ], "offsets": [ [ 15, 31 ] ], "normalized": [] }, { "id": "3907", "type": "protein_family_or_group", "text": [ "defective transcription factor" ], ...
[]
[]
[]
3959
95373165
[ { "id": "3960", "type": "title", "text": [ "Restoration of the Epstein-Barr virus ZEBRA protein's capacity to disrupt latency by the addition of heterologous activation regions." ], "offsets": [ [ 0, 133 ] ] }, { "id": "3961", "type": "abstract",...
[ { "id": "3962", "type": "protein_molecule", "text": [ "Epstein-Barr virus ZEBRA protein" ], "offsets": [ [ 19, 51 ] ], "normalized": [] }, { "id": "3963", "type": "virus", "text": [ "Epstein-Barr virus" ], "offsets": [ ...
[]
[]
[]
3997
95362854
[ { "id": "3998", "type": "title", "text": [ "Interleukin 4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-gamma activation site-like sequence upstream of the I epsilon exon in a human B cell line. Evidence for the involvement of Janus ...
[ { "id": "4000", "type": "protein_molecule", "text": [ "Interleukin 4" ], "offsets": [ [ 0, 13 ] ], "normalized": [] }, { "id": "4001", "type": "other_name", "text": [ "signal transducer" ], "offsets": [ [ 26, ...
[]
[]
[]
4061
95329724
[ { "id": "4062", "type": "title", "text": [ "Does activation of the TAL1 gene occur in a majority of patients with T-cell acute lymphoblastic leukemia? A pediatric oncology group study." ], "offsets": [ [ 0, 140 ] ] }, { "id": "4063", "type": "abs...
[ { "id": "4064", "type": "DNA_domain_or_region", "text": [ "TAL1 gene" ], "offsets": [ [ 23, 32 ] ], "normalized": [] }, { "id": "4065", "type": "multi_cell", "text": [ "patients" ], "offsets": [ [ 56, 6...
[]
[]
[]
4118
95374911
[ { "id": "4119", "type": "title", "text": [ "Expression of erythroid-specific genes in acute megakaryoblastic leukaemia and transient myeloproliferative disorder in Down's syndrome." ], "offsets": [ [ 0, 136 ] ] }, { "id": "4120", "type": "abstrac...
[ { "id": "4121", "type": "DNA_family_or_group", "text": [ "erythroid-specific genes" ], "offsets": [ [ 14, 38 ] ], "normalized": [] }, { "id": "4122", "type": "other_name", "text": [ "acute megakaryoblastic leukaemia" ], "off...
[]
[]
[]
4158
95308691
[ { "id": "4159", "type": "title", "text": [ "Expression of Ah receptor (TCDD receptor) during human monocytic differentiation." ], "offsets": [ [ 0, 81 ] ] }, { "id": "4160", "type": "abstract", "text": [ "We have previously found a high...
[ { "id": "4161", "type": "protein_molecule", "text": [ "Ah receptor" ], "offsets": [ [ 14, 25 ] ], "normalized": [] }, { "id": "4162", "type": "protein_molecule", "text": [ "TCDD receptor" ], "offsets": [ [ 27, ...
[]
[]
[]
4222
95261059
[ { "id": "4223", "type": "title", "text": [ "Neutrophils and monocytes express high levels of PU.1 (Spi-1) but not Spi-B." ], "offsets": [ [ 0, 76 ] ] }, { "id": "4224", "type": "abstract", "text": [ "PU.1 (the Spi-1 oncogene) and Spi-B ...
[ { "id": "4225", "type": "cell_type", "text": [ "Neutrophils" ], "offsets": [ [ 0, 11 ] ], "normalized": [] }, { "id": "4226", "type": "cell_type", "text": [ "monocytes" ], "offsets": [ [ 16, 25 ] ...
[]
[]
[]
4296
95244883
[ { "id": "4297", "type": "title", "text": [ "Identification of a major positive regulatory element located 5' to the human zeta-globin gene." ], "offsets": [ [ 0, 95 ] ] }, { "id": "4298", "type": "abstract", "text": [ "The function of t...
[ { "id": "4299", "type": "DNA_family_or_group", "text": [ "positive regulatory element" ], "offsets": [ [ 26, 53 ] ], "normalized": [] }, { "id": "4300", "type": "DNA_domain_or_region", "text": [ "human zeta-globin gene" ], "...
[]
[]
[]
4356
95247773
[ { "id": "4357", "type": "title", "text": [ "Analysis of the role of protein kinase C-alpha, -epsilon, and -zeta in T cell activation." ], "offsets": [ [ 0, 89 ] ] }, { "id": "4358", "type": "abstract", "text": [ "T cells express multipl...
[ { "id": "4359", "type": "(AND protein_molecule protein_molecule protein_molecule)", "text": [ "protein kinase C-alpha, -epsilon, and -zeta" ], "offsets": [ [ 24, 67 ] ], "normalized": [] }, { "id": "4360", "type": "", "text": [ "pro...
[]
[]
[]
4416
95204946
[ { "id": "4417", "type": "title", "text": [ "Differences in binding of glucocorticoid receptor to DNA in steroid-resistant asthma." ], "offsets": [ [ 0, 85 ] ] }, { "id": "4418", "type": "abstract", "text": [ "Although glucocorticosteroi...
[ { "id": "4419", "type": "protein_family_or_group", "text": [ "glucocorticoid receptor" ], "offsets": [ [ 26, 49 ] ], "normalized": [] }, { "id": "4420", "type": "other_name", "text": [ "steroid-resistant asthma" ], "offsets"...
[]
[]
[]
4463
95195208
[ { "id": "4464", "type": "title", "text": [ "Interleukin-5 signaling in human eosinophils involves JAK2 tyrosine kinase and Stat1 alpha." ], "offsets": [ [ 0, 91 ] ] }, { "id": "4465", "type": "abstract", "text": [ "Signaling by a wide v...
[ { "id": "4466", "type": "other_name", "text": [ "Interleukin-5 signaling" ], "offsets": [ [ 0, 23 ] ], "normalized": [] }, { "id": "4467", "type": "protein_molecule", "text": [ "Interleukin-5" ], "offsets": [ [ ...
[]
[]
[]
4521
95373132
[ { "id": "4522", "type": "title", "text": [ "Infection and replication of Tat- human immunodeficiency viruses: genetic analyses of LTR and tat mutations in primary and long-term human lymphoid cells." ], "offsets": [ [ 0, 154 ] ] }, { "id": "4523", ...
[ { "id": "4524", "type": "virus", "text": [ "Tat- human immunodeficiency viruses" ], "offsets": [ [ 29, 64 ] ], "normalized": [] }, { "id": "4525", "type": "DNA_domain_or_region", "text": [ "LTR" ], "offsets": [ [ ...
[]
[]
[]
4592
95355848
[ { "id": "4593", "type": "title", "text": [ "Functional roles of the transcription factor Oct-2A and the high mobility group protein I/Y in HLA-DRA gene expression." ], "offsets": [ [ 0, 119 ] ] }, { "id": "4594", "type": "abstract", "text": [...
[ { "id": "4595", "type": "protein_molecule", "text": [ "transcription factor Oct-2A" ], "offsets": [ [ 24, 51 ] ], "normalized": [] }, { "id": "4596", "type": "protein_molecule", "text": [ "Oct-2A" ], "offsets": [ [ ...
[]
[]
[]
4655
95329723
[ { "id": "4656", "type": "title", "text": [ "Heterogeneous expression of Epstein-Barr virus latent proteins in endemic Burkitt's lymphoma." ], "offsets": [ [ 0, 93 ] ] }, { "id": "4657", "type": "abstract", "text": [ "Epstein-Barr virus ...
[ { "id": "4658", "type": "other_name", "text": [ "Heterogeneous expression" ], "offsets": [ [ 0, 24 ] ], "normalized": [] }, { "id": "4659", "type": "protein_family_or_group", "text": [ "Epstein-Barr virus latent proteins" ], ...
[]
[]
[]
4710
95325614
[ { "id": "4711", "type": "title", "text": [ "The activation of the Jak-STAT 1 signaling pathway by IL-5 in eosinophils." ], "offsets": [ [ 0, 74 ] ] }, { "id": "4712", "type": "abstract", "text": [ "The intracellular signal transduction ...
[ { "id": "4713", "type": "other_name", "text": [ "Jak-STAT 1 signaling pathway" ], "offsets": [ [ 22, 50 ] ], "normalized": [] }, { "id": "4714", "type": "protein_family_or_group", "text": [ "Jak" ], "offsets": [ [ ...
[]
[]
[]
4780
95298682
[ { "id": "4781", "type": "title", "text": [ "Reduced mitogenic stimulation of peripheral blood mononuclear cells as a prognostic parameter for the course of breast cancer: a prospective longitudinal study." ], "offsets": [ [ 0, 160 ] ] }, { "id": "478...
[ { "id": "4783", "type": "other_name", "text": [ "mitogenic stimulation" ], "offsets": [ [ 8, 29 ] ], "normalized": [] }, { "id": "4784", "type": "cell_type", "text": [ "peripheral blood mononuclear cells" ], "offsets": [ ...
[]
[]
[]
4842
95248083
[ { "id": "4843", "type": "title", "text": [ "Activation of transcription by binding of NF-E1 (YY1) to a newly identified element in the first exon of the human DR alpha gene." ], "offsets": [ [ 0, 129 ] ] }, { "id": "4844", "type": "abstract", ...
[ { "id": "4845", "type": "other_name", "text": [ "Activation of transcription" ], "offsets": [ [ 0, 27 ] ], "normalized": [] }, { "id": "4846", "type": "protein_molecule", "text": [ "NF-E1" ], "offsets": [ [ 42,...
[]
[]
[]
4881
95222739
[ { "id": "4882", "type": "title", "text": [ "Transcriptional activity of core binding factor-alpha (AML1) and beta subunits on murine leukemia virus enhancer cores." ], "offsets": [ [ 0, 119 ] ] }, { "id": "4883", "type": "abstract", "text": [...
[ { "id": "4884", "type": "other_name", "text": [ "Transcriptional activity" ], "offsets": [ [ 0, 24 ] ], "normalized": [] }, { "id": "4885", "type": "(AND protein_subunit protein_subunit)", "text": [ "core binding factor-alpha (AML1)...
[]
[]
[]
4961
95238477
[ { "id": "4962", "type": "title", "text": [ "Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms." ], "offsets": [ [ 0, 163 ] ] }, { "id": "...
[ { "id": "4964", "type": "protein_molecule", "text": [ "Interleukin (IL)-10" ], "offsets": [ [ 0, 19 ] ], "normalized": [] }, { "id": "4965", "type": "other_name", "text": [ "nuclear factor kappa B (NF kappa B) activation" ], ...
[]
[]
[]
5039
95190988
[ { "id": "5040", "type": "title", "text": [ "LMP-1 activates NF-kappa B by targeting the inhibitory molecule I kappa B alpha." ], "offsets": [ [ 0, 80 ] ] }, { "id": "5041", "type": "abstract", "text": [ "LMP-1, an Epstein-Barr virus mem...
[ { "id": "5042", "type": "protein_molecule", "text": [ "LMP-1" ], "offsets": [ [ 0, 5 ] ], "normalized": [] }, { "id": "5043", "type": "protein_molecule", "text": [ "NF-kappa B" ], "offsets": [ [ 16, 26 ...
[]
[]
[]
5096
95197545
[ { "id": "5097", "type": "title", "text": [ "Identification of human TR2 orphan receptor response element in the transcriptional initiation site of the simian virus 40 major late promoter [published erratum appears in J Biol Chem 1995 Nov 3;270(44):26721]" ], "offsets": [ [ 0,...
[ { "id": "5099", "type": "DNA_domain_or_region", "text": [ "human TR2 orphan receptor response element" ], "offsets": [ [ 18, 60 ] ], "normalized": [] }, { "id": "5100", "type": "protein_molecule", "text": [ "human TR2 orphan recepto...
[]
[]
[]
5149
95161757
[ { "id": "5150", "type": "title", "text": [ "Detection of the chromosome 16 CBF beta-MYH11 fusion transcript in myelomonocytic leukemias." ], "offsets": [ [ 0, 92 ] ] }, { "id": "5151", "type": "abstract", "text": [ "Karyotypic detection...
[ { "id": "5152", "type": "RNA_molecule", "text": [ "chromosome 16 CBF beta-MYH11 fusion transcript" ], "offsets": [ [ 17, 63 ] ], "normalized": [] }, { "id": "5153", "type": "DNA_molecule", "text": [ "chromosome 16" ], "offse...
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[]
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5214
95163587
[ { "id": "5215", "type": "title", "text": [ "HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state." ], "offsets": [ [ 0, 110 ] ] }, { "id": "5216", "type": "abstract", "text": [ "T...
[ { "id": "5217", "type": "protein_molecule", "text": [ "HIV-1 Tat" ], "offsets": [ [ 0, 9 ] ], "normalized": [] }, { "id": "5218", "type": "virus", "text": [ "HIV-1" ], "offsets": [ [ 0, 5 ] ],...
[]
[]
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5286
95261816
[ { "id": "5287", "type": "title", "text": [ "The use of glucocorticoids in acute lymphoblastic leukemia of childhood. Molecular, cellular, and clinical considerations." ], "offsets": [ [ 0, 122 ] ] }, { "id": "5288", "type": "abstract", "text"...
[ { "id": "5289", "type": "lipid", "text": [ "glucocorticoids" ], "offsets": [ [ 11, 26 ] ], "normalized": [] }, { "id": "5290", "type": "other_name", "text": [ "acute lymphoblastic leukemia" ], "offsets": [ [ 30...
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[]
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5315
95074873
[ { "id": "5316", "type": "title", "text": [ "Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1." ], "offsets": [ [ 0, 127 ] ] }, { "id": "5317", "type": "abstract", "...
[ { "id": "5318", "type": "other_name", "text": [ "Epstein-Barr virus nuclear protein 2 transactivation" ], "offsets": [ [ 0, 52 ] ], "normalized": [] }, { "id": "5319", "type": "protein_molecule", "text": [ "Epstein-Barr virus nuclea...
[]
[]
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5395
96094166
[ { "id": "5396", "type": "title", "text": [ "Lymphocyte glucocorticoid receptor: predictor of sertraline response in adolescent major depressive disorder (MDD)." ], "offsets": [ [ 0, 115 ] ] }, { "id": "5397", "type": "abstract", "text": [ ...
[ { "id": "5398", "type": "protein_family_or_group", "text": [ "Lymphocyte glucocorticoid receptor" ], "offsets": [ [ 0, 34 ] ], "normalized": [] }, { "id": "5399", "type": "lipid", "text": [ "glucocorticoid" ], "offsets": [ ...
[]
[]
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5430
95074049
[ { "id": "5431", "type": "title", "text": [ "The role of NFATp in cyclosporin A-sensitive tumor necrosis factor-alpha gene transcription." ], "offsets": [ [ 0, 92 ] ] }, { "id": "5432", "type": "abstract", "text": [ "The tumor necrosis f...
[ { "id": "5433", "type": "protein_molecule", "text": [ "NFATp" ], "offsets": [ [ 12, 17 ] ], "normalized": [] }, { "id": "5434", "type": "other_name", "text": [ "cyclosporin A-sensitive tumor necrosis factor-alpha gene transcription"...
[]
[]
[]
5482
95197720
[ { "id": "5483", "type": "title", "text": [ "Regulation and specificity of MNDA expression in monocytes, macrophages, and leukemia/B lymphoma cell lines." ], "offsets": [ [ 0, 108 ] ] }, { "id": "5484", "type": "abstract", "text": [ "The...
[ { "id": "5485", "type": "other_name", "text": [ "MNDA expression" ], "offsets": [ [ 30, 45 ] ], "normalized": [] }, { "id": "5486", "type": "protein_molecule", "text": [ "MNDA" ], "offsets": [ [ 30, 34 ...
[]
[]
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5546
95053891
[ { "id": "5547", "type": "title", "text": [ "DNA-binding studies of the Epstein-Barr virus nuclear antigen 2 (EBNA-2): evidence for complex formation by latent membrane protein gene promoter-binding proteins in EBNA-2-positive cell lines." ], "offsets": [ [ 0, 193 ...
[ { "id": "5549", "type": "protein_molecule", "text": [ "Epstein-Barr virus nuclear antigen 2" ], "offsets": [ [ 27, 63 ] ], "normalized": [] }, { "id": "5550", "type": "virus", "text": [ "Epstein-Barr virus" ], "offsets": [ ...
[]
[]
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5615
95015835
[ { "id": "5616", "type": "title", "text": [ "Simultaneous activation of Ig and Oct-2 synthesis and reduction of surface MHC class II expression by IL-6." ], "offsets": [ [ 0, 107 ] ] }, { "id": "5617", "type": "abstract", "text": [ "Term...
[ { "id": "5618", "type": "protein_family_or_group", "text": [ "Ig" ], "offsets": [ [ 27, 29 ] ], "normalized": [] }, { "id": "5619", "type": "other_name", "text": [ "Oct-2 synthesis" ], "offsets": [ [ 34, ...
[]
[]
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5654
95127210
[ { "id": "5655", "type": "title", "text": [ "T-cell functional regions of the human IL-3 proximal promoter." ], "offsets": [ [ 0, 62 ] ] }, { "id": "5656", "type": "abstract", "text": [ "The human interleukin-3 (IL-3) gene is expressed a...
[ { "id": "5657", "type": "DNA_domain_or_region", "text": [ "T-cell functional regions" ], "offsets": [ [ 0, 25 ] ], "normalized": [] }, { "id": "5658", "type": "DNA_domain_or_region", "text": [ "human IL-3 proximal promoter" ], ...
[]
[]
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