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22016685
[ { "id": "5", "type": "title", "text": [ "A novel missense mutation Asp506Gly in Exon 13 of the F11 gene in an asymptomatic Korean woman with mild factor XI deficiency." ], "offsets": [ [ 0, 126 ] ] }, { "id": "6", "type": "abstract", "text": ...
[ { "id": "1", "type": "ProteinMutation", "text": [ "Asp506Gly" ], "offsets": [ [ 26, 35 ] ], "normalized": [] }, { "id": "2", "type": "DNAMutation", "text": [ "c.1517A>G" ], "offsets": [ [ 1109, 1118 ...
[]
[]
[]
7
21850008
[ { "id": "18", "type": "title", "text": [ "Mutations in mitochondrially encoded complex I enzyme as the second common cause in a cohort of Chinese patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes." ], "offsets": [ [ 0, 199 ...
[ { "id": "8", "type": "DNAMutation", "text": [ "A3243G" ], "offsets": [ [ 727, 733 ] ], "normalized": [] }, { "id": "9", "type": "DNAMutation", "text": [ "G13513A" ], "offsets": [ [ 856, 863 ] ...
[]
[]
[]
20
22104738
[ { "id": "24", "type": "title", "text": [ "Novel compound heterozygous mutation of MLYCD in a Chinese patient with malonic aciduria." ], "offsets": [ [ 0, 89 ] ] }, { "id": "25", "type": "abstract", "text": [ "A 3-year-old Chinese boy pr...
[ { "id": "21", "type": "DNAMutation", "text": [ "c.920T>G" ], "offsets": [ [ 466, 474 ] ], "normalized": [] }, { "id": "22", "type": "ProteinMutation", "text": [ "p.Leu307Arg" ], "offsets": [ [ 476, 487 ...
[]
[]
[]
26
22295085
[ { "id": "27", "type": "title", "text": [ "Genetic and epigenetic alterations of the NF2 gene in sporadic vestibular schwannomas." ], "offsets": [ [ 0, 86 ] ] }, { "id": "28", "type": "abstract", "text": [ "BACKGROUND: Mutations in the n...
[]
[]
[]
[]
29
22174939
[ { "id": "30", "type": "title", "text": [ "RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients." ], "offsets": [ [ 0, 84 ] ] }, { "id": "31", "type": "abstract", "text": [ "Rare (RVs) and common variants o...
[]
[]
[]
[]
32
21943124
[ { "id": "33", "type": "title", "text": [ "A deletion of FGFR2 creating a chimeric IIIb/IIIc exon in a child with Apert syndrome." ], "offsets": [ [ 0, 86 ] ] }, { "id": "34", "type": "abstract", "text": [ "BACKGROUND: Signalling by fibr...
[]
[]
[]
[]
35
21779184
[ { "id": "36", "type": "title", "text": [ "Detection of a-thalassemia-1 Southeast Asian and Thai type deletions and b-thalassemia 3.5-kb deletion by single-tube multiplex real-time PCR with SYBR Green1 and high-resolution melting analysis." ], "offsets": [ [ 0, 196 ...
[]
[]
[]
[]
38
21640722
[ { "id": "39", "type": "title", "text": [ "Xeroderma pigmentosum variant: complementary molecular approaches to detect a 13 base pair deletion in the DNA polymerase eta gene." ], "offsets": [ [ 0, 131 ] ] }, { "id": "40", "type": "abstract", "...
[]
[]
[]
[]
41
21499297
[ { "id": "44", "type": "title", "text": [ "C10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancer." ], "offsets": [ [ 0, 159 ] ] }, { "id": "45", ...
[ { "id": "42", "type": "DNAMutation", "text": [ "C>T" ], "offsets": [ [ 1547, 1550 ] ], "normalized": [] }, { "id": "43", "type": "SNP", "text": [ "rs2297882" ], "offsets": [ [ 1552, 1561 ] ], ...
[]
[]
[]
46
21695597
[ { "id": "53", "type": "title", "text": [ "MHC region and risk of systemic lupus erythematosus in African American women." ], "offsets": [ [ 0, 78 ] ] }, { "id": "54", "type": "abstract", "text": [ "The major histocompatibility complex (...
[ { "id": "47", "type": "SNP", "text": [ "rs9271366" ], "offsets": [ [ 891, 900 ] ], "normalized": [] }, { "id": "48", "type": "SNP", "text": [ "rs204890" ], "offsets": [ [ 1025, 1033 ] ], "...
[]
[]
[]
55
21629979
[ { "id": "56", "type": "title", "text": [ "Molecular and clinical analysis of glioblastoma with an oligodendroglial component (GBMO)." ], "offsets": [ [ 0, 90 ] ] }, { "id": "57", "type": "abstract", "text": [ "The genetic and clinical f...
[]
[]
[]
[]
58
22048266
[ { "id": "63", "type": "title", "text": [ "Exploratory investigation on functional significance of ETS2 and SIM2 genes in Down syndrome." ], "offsets": [ [ 0, 93 ] ] }, { "id": "64", "type": "abstract", "text": [ "Trisomy of the 21{st} c...
[ { "id": "59", "type": "SNP", "text": [ "rs461155" ], "offsets": [ [ 804, 812 ] ], "normalized": [] }, { "id": "60", "type": "SNP", "text": [ "rs2073601" ], "offsets": [ [ 900, 909 ] ], "no...
[]
[]
[]
65
22028770
[ { "id": "77", "type": "title", "text": [ "APOE genotype-function relationship: evidence of -491 A/T promoter polymorphism modifying transcription control but not type 2 diabetes risk." ], "offsets": [ [ 0, 141 ] ] }, { "id": "78", "type": "abstra...
[ { "id": "66", "type": "DNAMutation", "text": [ "-491 A/T" ], "offsets": [ [ 49, 57 ] ], "normalized": [] }, { "id": "67", "type": "DNAMutation", "text": [ "-491A/T" ], "offsets": [ [ 745, 752 ] ...
[]
[]
[]
79
21771880
[ { "id": "80", "type": "title", "text": [ "Resequencing of IRS2 reveals rare variants for obesity but not fasting glucose homeostasis in Hispanic children." ], "offsets": [ [ 0, 112 ] ] }, { "id": "81", "type": "abstract", "text": [ "Our...
[]
[]
[]
[]
82
21790735
[ { "id": "83", "type": "title", "text": [ "A large heterozygous deletion including the entire C1 inhibitor gene in a sporadic case of hereditary angio-oedema." ], "offsets": [ [ 0, 115 ] ] }, { "id": "84", "type": "abstract", "text": [ "...
[]
[]
[]
[]
85
21506149
[ { "id": "86", "type": "title", "text": [ "Phenotype of the 202 adenine deletion in the parkin gene: 40 years of follow-up." ], "offsets": [ [ 0, 80 ] ] }, { "id": "87", "type": "abstract", "text": [ "BACKGROUND: We describe the four dec...
[]
[]
[]
[]
88
21904390
[ { "id": "94", "type": "title", "text": [ "Two novel mutations of the PAX6 gene causing different phenotype in a cohort of Chinese patients." ], "offsets": [ [ 0, 97 ] ] }, { "id": "95", "type": "abstract", "text": [ "PURPOSE: Aniridia (...
[ { "id": "89", "type": "DNAMutation", "text": [ "c.357-3C>G" ], "offsets": [ [ 1245, 1255 ] ], "normalized": [] }, { "id": "90", "type": "ProteinMutation", "text": [ "p.Ser119fsX" ], "offsets": [ [ 1257, ...
[]
[]
[]
96
21496008
[ { "id": "105", "type": "title", "text": [ "Screening and cell-based assessment of mutations in the Aristaless-related homeobox (ARX) gene." ], "offsets": [ [ 0, 95 ] ] }, { "id": "106", "type": "abstract", "text": [ "ARX mutations cause...
[ { "id": "97", "type": "DNAMutation", "text": [ "c.304ins(GCG)" ], "offsets": [ [ 524, 537 ] ], "normalized": [] }, { "id": "98", "type": "DNAMutation", "text": [ "c.429_452dup" ], "offsets": [ [ 563, 57...
[]
[]
[]
107
21717135
[ { "id": "108", "type": "title", "text": [ "Variation in genotype and higher virulence of a strain of Sporothrix schenckii causing disseminated cutaneous sporotrichosis." ], "offsets": [ [ 0, 125 ] ] }, { "id": "109", "type": "abstract", "text...
[]
[]
[]
[]
110
21976953
[ { "id": "114", "type": "title", "text": [ "Identification of a novel FBN1 gene mutation in a Chinese family with Marfan syndrome." ], "offsets": [ [ 0, 86 ] ] }, { "id": "115", "type": "abstract", "text": [ "PURPOSE: To identify the mut...
[ { "id": "111", "type": "DNAMutation", "text": [ "c.3703T>C" ], "offsets": [ [ 1018, 1027 ] ], "normalized": [] }, { "id": "112", "type": "ProteinMutation", "text": [ "p.S1235P" ], "offsets": [ [ 1154, 1...
[]
[]
[]
116
21546516
[ { "id": "117", "type": "title", "text": [ "The 57 kb deletion in cystinosis patients extends into TRPV1 causing dysregulation of transcription in peripheral blood mononuclear cells." ], "offsets": [ [ 0, 138 ] ] }, { "id": "118", "type": "abstrac...
[]
[]
[]
[]
119
21799811
[ { "id": "125", "type": "title", "text": [ "Strong association of 677 C>T substitution in the MTHFR gene with male infertility--a study on an indian population and a meta-analysis." ], "offsets": [ [ 0, 136 ] ] }, { "id": "126", "type": "abstract"...
[ { "id": "120", "type": "DNAMutation", "text": [ "677 C>T" ], "offsets": [ [ 22, 29 ] ], "normalized": [] }, { "id": "121", "type": "DNAMutation", "text": [ "677C>T" ], "offsets": [ [ 360, 366 ] ...
[]
[]
[]
127
21976404
[ { "id": "128", "type": "title", "text": [ "Angiotensin-converting enzyme (ACE) serum levels and gene polymorphism in Egyptian patients with systemic lupus erythematosus." ], "offsets": [ [ 0, 126 ] ] }, { "id": "129", "type": "abstract", "tex...
[]
[]
[]
[]
130
21879313
[ { "id": "135", "type": "title", "text": [ "Genotype rs8099917 near the IL28B gene and amino acid substitution at position 70 in the core region of the hepatitis C virus are determinants of serum apolipoprotein B-100 concentration in chronic hepatitis C." ], "offsets": [ [ 0, ...
[ { "id": "131", "type": "SNP", "text": [ "rs8099917" ], "offsets": [ [ 9, 18 ] ], "normalized": [] }, { "id": "132", "type": "SNP", "text": [ "rs8099917" ], "offsets": [ [ 1047, 1056 ] ], "...
[]
[]
[]
137
20854438
[ { "id": "141", "type": "title", "text": [ "SLURP1 mutation-impaired T-cell activation in a family with mal de Meleda." ], "offsets": [ [ 0, 74 ] ] }, { "id": "142", "type": "abstract", "text": [ "BACKGROUND: Mal de Meleda (MDM) is palmo...
[ { "id": "138", "type": "ProteinMutation", "text": [ "G86R" ], "offsets": [ [ 1233, 1237 ] ], "normalized": [] }, { "id": "139", "type": "ProteinMutation", "text": [ "G86R" ], "offsets": [ [ 1496, 1500 ...
[]
[]
[]
143
20728296
[ { "id": "144", "type": "title", "text": [ "Interstitial deletion of 13q14.13-q32.3 presenting with Arima syndrome and bilateral retinoblastoma." ], "offsets": [ [ 0, 100 ] ] }, { "id": "145", "type": "abstract", "text": [ "A patient wit...
[]
[]
[]
[]
146
20887110
[ { "id": "151", "type": "title", "text": [ "Impact of 5,10-methylenetetrahydrofolate reductase gene polymorphism on neural tube defects." ], "offsets": [ [ 0, 92 ] ] }, { "id": "152", "type": "abstract", "text": [ "OBJECT: Neural tube de...
[ { "id": "147", "type": "DNAMutation", "text": [ "C-->T transition at nucleotide 677" ], "offsets": [ [ 471, 505 ] ], "normalized": [] }, { "id": "148", "type": "DNAMutation", "text": [ "677 C-->T" ], "offsets": [ [ ...
[]
[]
[]
153
20602574
[ { "id": "157", "type": "title", "text": [ "Bikunin and a1-microglobulin/bikunin precursor (AMBP) gene mutational screening in patients with kidney stones: a case-control study." ], "offsets": [ [ 0, 133 ] ] }, { "id": "158", "type": "abstract", ...
[ { "id": "154", "type": "DNAMutation", "text": [ "T-189C" ], "offsets": [ [ 1238, 1244 ] ], "normalized": [] }, { "id": "155", "type": "DNAMutation", "text": [ "G-218C" ], "offsets": [ [ 1321, 1327 ...
[]
[]
[]
159
21080147
[ { "id": "162", "type": "title", "text": [ "Novel CRELD1 gene mutations in patients with atrioventricular septal defect." ], "offsets": [ [ 0, 76 ] ] }, { "id": "163", "type": "abstract", "text": [ "BACKGROUND: Atrioventricular septal de...
[ { "id": "160", "type": "DNAMutation", "text": [ "c.973G>A" ], "offsets": [ [ 1203, 1211 ] ], "normalized": [] }, { "id": "161", "type": "ProteinMutation", "text": [ "E325K" ], "offsets": [ [ 1307, 1312 ...
[]
[]
[]
164
20708777
[ { "id": "175", "type": "title", "text": [ "Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas." ], "offsets": [ [ 0, 154 ] ] }, { "id": "176", ...
[ { "id": "165", "type": "SNP", "text": [ "rs1799998" ], "offsets": [ [ 791, 800 ] ], "normalized": [] }, { "id": "166", "type": "DNAMutation", "text": [ "C-344 T" ], "offsets": [ [ 802, 809 ] ]...
[]
[]
[]
177
21059483
[ { "id": "178", "type": "title", "text": [ "The GALT rush: high carrier frequency of an unusual deletion mutation of the GALT gene in the Ashkenazi population." ], "offsets": [ [ 0, 115 ] ] }, { "id": "179", "type": "abstract", "text": [ ...
[]
[]
[]
[]
180
21103668
[ { "id": "181", "type": "title", "text": [ "Characterisation of two novel large F8 deletions in patients with severe haemophilia A and factor VIII inhibitors." ], "offsets": [ [ 0, 114 ] ] }, { "id": "182", "type": "abstract", "text": [ ...
[]
[]
[]
[]
183
20682662
[ { "id": "184", "type": "title", "text": [ "Lack of association of C-C chemokine receptor 5 /\\32 deletion status with rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, and disease severity." ], "offsets": [ [ 0, 164 ] ] }, { "id": ...
[]
[]
[]
[]
186
20806042
[ { "id": "190", "type": "title", "text": [ "A novel mutation in GJA8 causing congenital cataract-microcornea syndrome in a Chinese pedigree." ], "offsets": [ [ 0, 96 ] ] }, { "id": "191", "type": "abstract", "text": [ "PURPOSE: To identi...
[ { "id": "187", "type": "DNAMutation", "text": [ "c.592C-->T" ], "offsets": [ [ 647, 657 ] ], "normalized": [] }, { "id": "188", "type": "ProteinMutation", "text": [ "p.R198W" ], "offsets": [ [ 858, 865 ...
[]
[]
[]
192
21159032
[ { "id": "193", "type": "title", "text": [ "Alpha2B-adrenergic receptor insertion/deletion polymorphism in women with spontaneous recurrent abortions." ], "offsets": [ [ 0, 106 ] ] }, { "id": "194", "type": "abstract", "text": [ "AIM: Th...
[]
[]
[]
[]
195
20949073
[ { "id": "198", "type": "title", "text": [ "Alternative splicing at a NAGNAG acceptor site as a novel phenotype modifier." ], "offsets": [ [ 0, 77 ] ] }, { "id": "199", "type": "abstract", "text": [ "Approximately 30% of alleles causing ...
[ { "id": "196", "type": "ProteinMutation", "text": [ "E831X" ], "offsets": [ [ 575, 580 ] ], "normalized": [] }, { "id": "197", "type": "DNAMutation", "text": [ "2623G>T" ], "offsets": [ [ 591, 598 ...
[]
[]
[]
200
20651814
[ { "id": "201", "type": "title", "text": [ "Lack of association between ADRA2B-4825 gene insertion/deletion polymorphism and migraine in Chinese Han population." ], "offsets": [ [ 0, 116 ] ] }, { "id": "202", "type": "abstract", "text": [ ...
[]
[]
[]
[]
203
20534762
[ { "id": "209", "type": "title", "text": [ "Two novel mutations of the TSH-beta subunit gene underlying congenital central hypothyroidism undetectable in neonatal TSH screening." ], "offsets": [ [ 0, 133 ] ] }, { "id": "210", "type": "abstract", ...
[ { "id": "204", "type": "DNAMutation", "text": [ "313delT" ], "offsets": [ [ 1066, 1073 ] ], "normalized": [] }, { "id": "205", "type": "ProteinMutation", "text": [ "C105Vfs114X" ], "offsets": [ [ 1075, ...
[]
[]
[]
211
20529581
[ { "id": "214", "type": "title", "text": [ "A novel point mutation in CD18 causing leukocyte adhesion deficiency in a Chinese patient." ], "offsets": [ [ 0, 90 ] ] }, { "id": "215", "type": "abstract", "text": [ "BACKGROUND: Leukocyte ad...
[ { "id": "212", "type": "DNAMutation", "text": [ "c.899A > T" ], "offsets": [ [ 1150, 1160 ] ], "normalized": [] }, { "id": "213", "type": "ProteinMutation", "text": [ "Asp 300 Val" ], "offsets": [ [ 1421, ...
[]
[]
[]
216
20523265
[ { "id": "230", "type": "title", "text": [ "Association study of complement factor H, C2, CFB, and C3 and age-related macular degeneration in a Han Chinese population." ], "offsets": [ [ 0, 123 ] ] }, { "id": "231", "type": "abstract", "text":...
[ { "id": "217", "type": "SNP", "text": [ "rs3753394" ], "offsets": [ [ 906, 915 ] ], "normalized": [] }, { "id": "218", "type": "SNP", "text": [ "rs800292" ], "offsets": [ [ 930, 938 ] ], "...
[]
[]
[]
232
20352162
[ { "id": "233", "type": "title", "text": [ "4G/5G polymorphism and haplotypes of SERPINE1 in atherosclerotic diseases of coronary arteries." ], "offsets": [ [ 0, 95 ] ] }, { "id": "234", "type": "abstract", "text": [ "We assessed the ass...
[]
[]
[]
[]
235
20202300
[ { "id": "236", "type": "title", "text": [ "Recent nosocomial transmission and genotypes of multidrug-resistant Mycobacterium tuberculosis." ], "offsets": [ [ 0, 95 ] ] }, { "id": "237", "type": "abstract", "text": [ "SETTING: Multidrug-...
[]
[]
[]
[]
238
20126413
[ { "id": "239", "type": "title", "text": [ "U87MG decoded: the genomic sequence of a cytogenetically aberrant human cancer cell line." ], "offsets": [ [ 0, 89 ] ] }, { "id": "240", "type": "abstract", "text": [ "U87MG is a commonly studi...
[]
[]
[]
[]
241
20113448
[ { "id": "242", "type": "title", "text": [ "Development and validation of a SYBR Green I-based real-time polymerase chain reaction method for detection of haptoglobin gene deletion in clinical materials." ], "offsets": [ [ 0, 159 ] ] }, { "id": "243",...
[]
[]
[]
[]
244
20017074
[ { "id": "245", "type": "title", "text": [ "Investigation of SERPINE1 genetic polymorphism in Macedonian patients with occlusive artery disease and deep vein thrombosis." ], "offsets": [ [ 0, 125 ] ] }, { "id": "246", "type": "abstract", "text...
[]
[]
[]
[]
247
20005218
[ { "id": "257", "type": "title", "text": [ "A potential regulatory single nucleotide polymorphism in the promoter of the Klotho gene may be associated with essential hypertension in the Chinese Han population." ], "offsets": [ [ 0, 165 ] ] }, { "id": ...
[ { "id": "248", "type": "DNAMutation", "text": [ "G-395A" ], "offsets": [ [ 302, 308 ] ], "normalized": [] }, { "id": "249", "type": "DNAMutation", "text": [ "G-395A" ], "offsets": [ [ 471, 477 ] ...
[]
[]
[]
259
19897031
[ { "id": "264", "type": "title", "text": [ "An intronic polymorphism of IRF4 gene influences gene transcription in vitro and shows a risk association with childhood acute lymphoblastic leukemia in males." ], "offsets": [ [ 0, 159 ] ] }, { "id": "265",...
[ { "id": "260", "type": "SNP", "text": [ "rs12203592" ], "offsets": [ [ 775, 785 ] ], "normalized": [] }, { "id": "261", "type": "DNAMutation", "text": [ "C>T" ], "offsets": [ [ 896, 899 ] ], ...
[]
[]
[]
266
19766614
[ { "id": "270", "type": "title", "text": [ "A novel insertion mutation in the SEDL gene results in X-linked spondyloepiphyseal dysplasia tarda in a large Chinese pedigree." ], "offsets": [ [ 0, 127 ] ] }, { "id": "271", "type": "abstract", "te...
[ { "id": "267", "type": "DNAMutation", "text": [ "c.370-371insA" ], "offsets": [ [ 980, 993 ] ], "normalized": [] }, { "id": "268", "type": "ProteinMutation", "text": [ "p.S124fsX127" ], "offsets": [ [ 1090, ...
[]
[]
[]
272
19730022
[ { "id": "273", "type": "title", "text": [ "Congestive heart failure with rhabdomyolysis and acute renal failure in a manifesting female carrier of Duchenne muscular dystrophy with duplication of dystrophin gene." ], "offsets": [ [ 0, 168 ] ] }, { "id...
[]
[]
[]
[]
275
19681861
[ { "id": "277", "type": "title", "text": [ "Forty-two novel COL7A1 mutations and the role of a frequent single nucleotide polymorphism in the MMP1 promoter in modulation of disease severity in a large European dystrophic epidermolysis bullosa cohort." ], "offsets": [ [ 0, ...
[ { "id": "276", "type": "SNP", "text": [ "rs1799750" ], "offsets": [ [ 431, 440 ] ], "normalized": [] } ]
[]
[]
[]
279
19559455
[ { "id": "281", "type": "title", "text": [ "A combination of defective DNA and protective host factors are found in a set of HIV-1 ancestral LTNPs." ], "offsets": [ [ 0, 103 ] ] }, { "id": "282", "type": "abstract", "text": [ "We studied...
[ { "id": "280", "type": "DNAMutation", "text": [ "Delta32" ], "offsets": [ [ 982, 989 ] ], "normalized": [] } ]
[]
[]
[]
283
19542096
[ { "id": "284", "type": "title", "text": [ "Mutation of SYNE-1, encoding an essential component of the nuclear lamina, is responsible for autosomal recessive arthrogryposis." ], "offsets": [ [ 0, 129 ] ] }, { "id": "285", "type": "abstract", "...
[]
[]
[]
[]
286
19477219
[ { "id": "287", "type": "title", "text": [ "Identified hidden genomic changes in mantle cell lymphoma using high-resolution single nucleotide polymorphism genomic array." ], "offsets": [ [ 0, 125 ] ] }, { "id": "288", "type": "abstract", "text...
[]
[]
[]
[]
289
19444361
[ { "id": "294", "type": "title", "text": [ "COL3A1 2209G>A is a predictor of pelvic organ prolapse." ], "offsets": [ [ 0, 55 ] ] }, { "id": "295", "type": "abstract", "text": [ "INTRODUCTION AND HYPOTHESIS: A familial tendency has been d...
[ { "id": "290", "type": "DNAMutation", "text": [ "2209G>A" ], "offsets": [ [ 7, 14 ] ], "normalized": [] }, { "id": "291", "type": "DNAMutation", "text": [ "2209G>A" ], "offsets": [ [ 842, 849 ] ...
[]
[]
[]
296
19429807
[ { "id": "300", "type": "title", "text": [ "A novel ATP7A gross deletion mutation in a Korean patient with Menkes disease." ], "offsets": [ [ 0, 78 ] ] }, { "id": "301", "type": "abstract", "text": [ "Menkes disease (MD, MIM 309400) is a...
[ { "id": "297", "type": "DNAMutation", "text": [ "c.3943G>A" ], "offsets": [ [ 582, 591 ] ], "normalized": [] }, { "id": "298", "type": "ProteinMutation", "text": [ "p.G1315R" ], "offsets": [ [ 593, 601 ...
[]
[]
[]
302
19394258
[ { "id": "304", "type": "title", "text": [ "The first founder DGUOK mutation associated with hepatocerebral mitochondrial DNA depletion syndrome." ], "offsets": [ [ 0, 101 ] ] }, { "id": "305", "type": "abstract", "text": [ "Deoxyguanosi...
[ { "id": "303", "type": "DNAMutation", "text": [ "c.444-62C>A" ], "offsets": [ [ 420, 431 ] ], "normalized": [] } ]
[]
[]
[]
306
19365571
[ { "id": "311", "type": "title", "text": [ "Macular corneal dystrophy in a Chinese family related with novel mutations of CHST6." ], "offsets": [ [ 0, 84 ] ] }, { "id": "312", "type": "abstract", "text": [ "PURPOSE: To identify mutations...
[ { "id": "307", "type": "DNAMutation", "text": [ "c.892C>T" ], "offsets": [ [ 1117, 1125 ] ], "normalized": [] }, { "id": "308", "type": "DNAMutation", "text": [ "c.1072T>C" ], "offsets": [ [ 1130, 1139 ...
[]
[]
[]
313
19298002
[ { "id": "316", "type": "title", "text": [ "Genetic polymorphism in chemokine CCL22 and susceptibility to Helicobacter pylori infection-related gastric carcinoma." ], "offsets": [ [ 0, 118 ] ] }, { "id": "317", "type": "abstract", "text": [ ...
[ { "id": "314", "type": "DNAMutation", "text": [ "16C-->A" ], "offsets": [ [ 956, 963 ] ], "normalized": [] }, { "id": "315", "type": "SNP", "text": [ "reference SNP no. 4359426" ], "offsets": [ [ 969, 9...
[]
[]
[]
318
19132389
[ { "id": "319", "type": "title", "text": [ "Impact of pepsinogen C polymorphism on individual susceptibility to gastric cancer and its precancerous conditions in a Northeast Chinese population." ], "offsets": [ [ 0, 149 ] ] }, { "id": "320", "type...
[]
[]
[]
[]
321
19129715
[ { "id": "325", "type": "title", "text": [ "Three novel IGFALS gene mutations resulting in total ALS and severe circulating IGF-I/IGFBP-3 deficiency in children of different ethnic origins." ], "offsets": [ [ 0, 145 ] ] }, { "id": "326", "type": "...
[ { "id": "322", "type": "DNAMutation", "text": [ "1308_1316 dup9" ], "offsets": [ [ 886, 900 ] ], "normalized": [] }, { "id": "323", "type": "ProteinMutation", "text": [ "C60S" ], "offsets": [ [ 1073, 10...
[]
[]
[]
327
19110214
[ { "id": "330", "type": "title", "text": [ "A recessive skeletal dysplasia, SEMD aggrecan type, results from a missense mutation affecting the C-type lectin domain of aggrecan." ], "offsets": [ [ 0, 132 ] ] }, { "id": "331", "type": "abstract", ...
[ { "id": "328", "type": "DNAMutation", "text": [ "c.6799G --> A" ], "offsets": [ [ 922, 935 ] ], "normalized": [] }, { "id": "329", "type": "ProteinMutation", "text": [ "p.D2267N" ], "offsets": [ [ 953, ...
[]
[]
[]
332
19101703
[ { "id": "333", "type": "title", "text": [ "Study of a Taiwanese family with oculopharyngeal muscular dystrophy." ], "offsets": [ [ 0, 68 ] ] }, { "id": "334", "type": "abstract", "text": [ "BACKGROUND: Oculopharyngeal muscular dystrophy...
[]
[]
[]
[]
335
19082493
[ { "id": "340", "type": "title", "text": [ "Combination of polymorphisms within 5' and 3' untranslated regions of thymidylate synthase gene modulates survival in 5 fluorouracil-treated colorectal cancer patients." ], "offsets": [ [ 0, 168 ] ] }, { "id...
[ { "id": "336", "type": "DNAMutation", "text": [ "G/C" ], "offsets": [ [ 412, 415 ] ], "normalized": [] }, { "id": "337", "type": "DNAMutation", "text": [ "ins/del 6 bp" ], "offsets": [ [ 886, 898 ...
[]
[]
[]
342
19047089
[ { "id": "343", "type": "title", "text": [ "Genome-wide loss of heterozygosity and uniparental disomy in BRCA1/2-associated ovarian carcinomas." ], "offsets": [ [ 0, 99 ] ] }, { "id": "344", "type": "abstract", "text": [ "PURPOSE: The im...
[]
[]
[]
[]
345
19037252
[ { "id": "346", "type": "title", "text": [ "Mutations in phospholipase C epsilon 1 are not sufficient to cause diffuse mesangial sclerosis." ], "offsets": [ [ 0, 95 ] ] }, { "id": "347", "type": "abstract", "text": [ "Diffuse mesangial s...
[]
[]
[]
[]
348
19012332
[ { "id": "350", "type": "title", "text": [ "Somatic TP53 mutation mosaicism in a patient with Li-Fraumeni syndrome." ], "offsets": [ [ 0, 71 ] ] }, { "id": "351", "type": "abstract", "text": [ "We present a girl who developed adrenocorti...
[ { "id": "349", "type": "ProteinMutation", "text": [ "Arg282Trp" ], "offsets": [ [ 415, 424 ] ], "normalized": [] } ]
[]
[]
[]
352
18838613
[ { "id": "353", "type": "title", "text": [ "A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups." ], "offsets": [ [ 0, ...
[]
[]
[]
[]
355
18827003
[ { "id": "362", "type": "title", "text": [ "A novel point mutation in the amino terminal domain of the human glucocorticoid receptor (hGR) gene enhancing hGR-mediated gene expression." ], "offsets": [ [ 0, 139 ] ] }, { "id": "363", "type": "abstra...
[ { "id": "356", "type": "DNAMutation", "text": [ "(G --> C) substitution at position 1201" ], "offsets": [ [ 558, 597 ] ], "normalized": [] }, { "id": "357", "type": "ProteinMutation", "text": [ "D401H" ], "offsets": [ ...
[]
[]
[]
364
18813858
[ { "id": "367", "type": "title", "text": [ "Novel mutations in the IRF6 gene in Brazilian families with Van der Woude syndrome." ], "offsets": [ [ 0, 83 ] ] }, { "id": "368", "type": "abstract", "text": [ "Van der Woude Syndrome (VWS) is...
[ { "id": "365", "type": "DNAMutation", "text": [ "520delG" ], "offsets": [ [ 624, 631 ] ], "normalized": [] }, { "id": "366", "type": "DNAMutation", "text": [ "T1135A" ], "offsets": [ [ 731, 737 ] ...
[]
[]
[]
369
18806880
[ { "id": "373", "type": "title", "text": [ "Genetics of Meesmann corneal dystrophy: a novel mutation in the keratin 3 gene in an asymptomatic family suggests genotype-phenotype correlation." ], "offsets": [ [ 0, 145 ] ] }, { "id": "374", "type": "...
[ { "id": "370", "type": "DNAMutation", "text": [ "1493A>T" ], "offsets": [ [ 1378, 1385 ] ], "normalized": [] }, { "id": "371", "type": "ProteinMutation", "text": [ "E498V" ], "offsets": [ [ 1510, 1515 ...
[]
[]
[]
375
18779591
[ { "id": "379", "type": "title", "text": [ "Identification of a gain-of-function mutation of the prolactin receptor in women with benign breast tumors." ], "offsets": [ [ 0, 107 ] ] }, { "id": "380", "type": "abstract", "text": [ "There ...
[ { "id": "376", "type": "ProteinMutation", "text": [ "Ile(146)-->Leu" ], "offsets": [ [ 806, 820 ] ], "normalized": [] }, { "id": "377", "type": "ProteinMutation", "text": [ "I146L" ], "offsets": [ [ 963, ...
[]
[]
[]
381
18704161
[ { "id": "382", "type": "title", "text": [ "Genetic variation in an individual human exome." ], "offsets": [ [ 0, 47 ] ] }, { "id": "383", "type": "abstract", "text": [ "There is much interest in characterizing the variation in a human i...
[]
[]
[]
[]
384
18398821
[ { "id": "385", "type": "title", "text": [ "Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients." ], "offsets": [ [ 0, 158 ] ] }, { "id": "386", ...
[]
[]
[]
[]
387
18385169
[ { "id": "392", "type": "title", "text": [ "TNFA -308G>A in two international population-based cohorts and risk of asthma." ], "offsets": [ [ 0, 78 ] ] }, { "id": "393", "type": "abstract", "text": [ "Genetic association studies have rel...
[ { "id": "388", "type": "DNAMutation", "text": [ "-308G>A" ], "offsets": [ [ 5, 12 ] ], "normalized": [] }, { "id": "389", "type": "DNAMutation", "text": [ "-308G>A" ], "offsets": [ [ 217, 224 ] ...
[]
[]
[]
394
18272172
[ { "id": "399", "type": "title", "text": [ "A splice site mutation in hERG leads to cryptic splicing in human long QT syndrome." ], "offsets": [ [ 0, 83 ] ] }, { "id": "400", "type": "abstract", "text": [ "Mutations in the human ether-a-...
[ { "id": "395", "type": "DNAMutation", "text": [ "2398+1G>C" ], "offsets": [ [ 261, 270 ] ], "normalized": [] }, { "id": "396", "type": "DNAMutation", "text": [ "2398+1G>C" ], "offsets": [ [ 397, 406 ...
[]
[]
[]
401
18270997
[ { "id": "408", "type": "title", "text": [ "Catechol-O-methyltransferase (COMT) gene variants: possible association of the Val158Met variant with opiate addiction in Hispanic women." ], "offsets": [ [ 0, 137 ] ] }, { "id": "409", "type": "abstract...
[ { "id": "402", "type": "ProteinMutation", "text": [ "Val158Met" ], "offsets": [ [ 79, 88 ] ], "normalized": [] }, { "id": "403", "type": "DNAMutation", "text": [ "G472A" ], "offsets": [ [ 341, 346 ...
[]
[]
[]
410
18266724
[ { "id": "413", "type": "title", "text": [ "Histamine-N-methyl transferase polymorphism and risk for migraine." ], "offsets": [ [ 0, 66 ] ] }, { "id": "414", "type": "abstract", "text": [ "BACKGROUND/OBJECTIVES: Histamine has been implic...
[ { "id": "411", "type": "DNAMutation", "text": [ "C314T" ], "offsets": [ [ 387, 392 ] ], "normalized": [] }, { "id": "412", "type": "ProteinMutation", "text": [ "Thr105Ile" ], "offsets": [ [ 429, 438 ...
[]
[]
[]
415
18164595
[ { "id": "419", "type": "title", "text": [ "Mutations in the hairless gene underlie APL in three families of Pakistani origin." ], "offsets": [ [ 0, 82 ] ] }, { "id": "420", "type": "abstract", "text": [ "BACKGROUND: Atrichia with papula...
[ { "id": "416", "type": "DNAMutation", "text": [ "1782-83delAG" ], "offsets": [ [ 1043, 1055 ] ], "normalized": [] }, { "id": "417", "type": "DNAMutation", "text": [ "3097delG" ], "offsets": [ [ 1173, 11...
[]
[]
[]
421
18046082
[ { "id": "424", "type": "title", "text": [ "Identification of apolipoprotein E Guangzhou (arginine 150 proline), a new variant associated with lipoprotein glomerulopathy." ], "offsets": [ [ 0, 126 ] ] }, { "id": "425", "type": "abstract", "tex...
[ { "id": "422", "type": "ProteinMutation", "text": [ "arginine 150 proline" ], "offsets": [ [ 46, 66 ] ], "normalized": [] }, { "id": "423", "type": "ProteinMutation", "text": [ "arginine 150 proline" ], "offsets": [ [ ...
[]
[]
[]
426
18036257
[ { "id": "427", "type": "title", "text": [ "Single nucleotide polymorphisms in bone turnover-related genes in Koreans: ethnic differences in linkage disequilibrium and haplotype." ], "offsets": [ [ 0, 134 ] ] }, { "id": "428", "type": "abstract", ...
[]
[]
[]
[]
429
17962469
[ { "id": "430", "type": "title", "text": [ "Novel TULP1 mutation causing leber congenital amaurosis or early onset retinal degeneration." ], "offsets": [ [ 0, 92 ] ] }, { "id": "431", "type": "abstract", "text": [ "PURPOSE: To report a l...
[]
[]
[]
[]
432
17951029
[ { "id": "436", "type": "title", "text": [ "Focal dermal hypoplasia resulting from a new nonsense mutation, p.E300X, in the PORCN gene." ], "offsets": [ [ 0, 91 ] ] }, { "id": "437", "type": "abstract", "text": [ "BACKGROUND: Focal derma...
[ { "id": "433", "type": "ProteinMutation", "text": [ "p.E300X" ], "offsets": [ [ 64, 71 ] ], "normalized": [] }, { "id": "434", "type": "DNAMutation", "text": [ "G>T substitution at nucleotide c.898" ], "offsets": [ [ ...
[]
[]
[]
438
17868390
[ { "id": "442", "type": "title", "text": [ "A novel DFNA5 mutation, IVS8+4 A>G, in the splice donor site of intron 8 causes late-onset non-syndromic hearing loss in a Chinese family." ], "offsets": [ [ 0, 138 ] ] }, { "id": "443", "type": "abstrac...
[ { "id": "439", "type": "DNAMutation", "text": [ "IVS8+4 A>G" ], "offsets": [ [ 24, 34 ] ], "normalized": [] }, { "id": "440", "type": "DNAMutation", "text": [ "IVS8+4 A>G" ], "offsets": [ [ 659, 669 ...
[]
[]
[]
444
17635946
[ { "id": "448", "type": "title", "text": [ "A novel point mutation in helix 11 of the ligand-binding domain of the human glucocorticoid receptor gene causing generalized glucocorticoid resistance." ], "offsets": [ [ 0, 152 ] ] }, { "id": "449", "t...
[ { "id": "445", "type": "DNAMutation", "text": [ "(T --> C) substitution at position 2209" ], "offsets": [ [ 793, 832 ] ], "normalized": [] }, { "id": "446", "type": "ProteinMutation", "text": [ "F737L" ], "offsets": [ ...
[]
[]
[]
450
17634480
[ { "id": "454", "type": "title", "text": [ "Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer." ], "offsets": [ [ 0, 109 ] ] }, { "id": "455", "type": "abstract", "text": [ "PURP...
[ { "id": "451", "type": "SNP", "text": [ "rs713041" ], "offsets": [ [ 797, 805 ] ], "normalized": [] }, { "id": "452", "type": "SNP", "text": [ "rs757229" ], "offsets": [ [ 810, 818 ] ], "n...
[]
[]
[]
456
17628794
[ { "id": "457", "type": "title", "text": [ "Manganese superoxide dismutase (Mn-SOD) gene polymorphisms in urolithiasis." ], "offsets": [ [ 0, 75 ] ] }, { "id": "458", "type": "abstract", "text": [ "Polymorphism in manganese superoxide di...
[]
[]
[]
[]
459
17615540
[ { "id": "463", "type": "title", "text": [ "A novel \"pearl box\" cataract associated with a mutation in the connexin 46 (GJA3) gene." ], "offsets": [ [ 0, 87 ] ] }, { "id": "464", "type": "abstract", "text": [ "PURPOSE: To undertake mut...
[ { "id": "460", "type": "DNAMutation", "text": [ "C260T" ], "offsets": [ [ 743, 748 ] ], "normalized": [] }, { "id": "461", "type": "DNAMutation", "text": [ "C260T" ], "offsets": [ [ 934, 939 ] ...
[]
[]
[]
465
17595233
[ { "id": "468", "type": "title", "text": [ "Mutations in pattern recognition receptor genes modulate seroreactivity to microbial antigens in patients with inflammatory bowel disease." ], "offsets": [ [ 0, 138 ] ] }, { "id": "469", "type": "abstrac...
[ { "id": "466", "type": "ProteinMutation", "text": [ "D299G" ], "offsets": [ [ 2271, 2276 ] ], "normalized": [] }, { "id": "467", "type": "ProteinMutation", "text": [ "P631H" ], "offsets": [ [ 2286, 2291...
[]
[]
[]
470
17495183
[ { "id": "480", "type": "title", "text": [ "Tenomodulin is associated with obesity and diabetes risk: the Finnish diabetes prevention study." ], "offsets": [ [ 0, 96 ] ] }, { "id": "481", "type": "abstract", "text": [ "We recently showed...
[ { "id": "471", "type": "SNP", "text": [ "rs5966709" ], "offsets": [ [ 824, 833 ] ], "normalized": [] }, { "id": "472", "type": "SNP", "text": [ "rs4828037" ], "offsets": [ [ 835, 844 ] ], ...
[]
[]
[]
482
17437275
[ { "id": "483", "type": "title", "text": [ "Novel mutations in the ZEB1 gene identified in Czech and British patients with posterior polymorphous corneal dystrophy." ], "offsets": [ [ 0, 120 ] ] }, { "id": "484", "type": "abstract", "text": [ ...
[]
[]
[]
[]
485
17426470
[ { "id": "486", "type": "title", "text": [ "3' Mutation of the APC gene and family history of FAP in a patient with apparently sporadic desmoid tumors." ], "offsets": [ [ 0, 107 ] ] }, { "id": "487", "type": "abstract", "text": [ "Desmoi...
[]
[]
[]
[]
488
17372760
[ { "id": "491", "type": "title", "text": [ "Atypical Rothmund-Thomson syndrome in a patient with compound heterozygous mutations in RECQL4 gene and phenotypic features in RECQL4 syndromes." ], "offsets": [ [ 0, 144 ] ] }, { "id": "492", "type": "a...
[ { "id": "489", "type": "DNAMutation", "text": [ "IVS10-1G>A" ], "offsets": [ [ 1086, 1096 ] ], "normalized": [] }, { "id": "490", "type": "ProteinMutation", "text": [ "L638P" ], "offsets": [ [ 1140, 114...
[]
[]
[]
493
17327916
[ { "id": "494", "type": "title", "text": [ "Genome-wide analysis of neuroblastomas using high-density single nucleotide polymorphism arrays." ], "offsets": [ [ 0, 96 ] ] }, { "id": "495", "type": "abstract", "text": [ "BACKGROUND: Neurob...
[]
[]
[]
[]
496
17311329
[ { "id": "497", "type": "title", "text": [ "Epstein Barr virus genotypes and LMP-1 variants in HIV-infected patients." ], "offsets": [ [ 0, 73 ] ] }, { "id": "498", "type": "abstract", "text": [ "Two Epstein Barr virus (EBV) genotypes: E...
[]
[]
[]
[]
499
17286451
[ { "id": "500", "type": "title", "text": [ "Retinoblastoma in India : microsatellite analysis and its application in genetic counseling." ], "offsets": [ [ 0, 92 ] ] }, { "id": "501", "type": "abstract", "text": [ "OBJECTIVES: This study...
[]
[]
[]
[]
502
17221831
[ { "id": "507", "type": "title", "text": [ "The G51S purine nucleoside phosphorylase polymorphism is associated with cognitive decline in Alzheimer's disease patients." ], "offsets": [ [ 0, 123 ] ] }, { "id": "508", "type": "abstract", "text":...
[ { "id": "503", "type": "ProteinMutation", "text": [ "G51S" ], "offsets": [ [ 4, 8 ] ], "normalized": [] }, { "id": "504", "type": "DNAMutation", "text": [ "G/A" ], "offsets": [ [ 703, 706 ] ],...
[]
[]
[]
509
17185385
[ { "id": "510", "type": "title", "text": [ "Two sites in the MAPT region confer genetic risk for Guam ALS/PDC and dementia." ], "offsets": [ [ 0, 79 ] ] }, { "id": "511", "type": "abstract", "text": [ "Unusual forms of amyotrophic latera...
[]
[]
[]
[]
512
17177139
[ { "id": "520", "type": "title", "text": [ "A novel mutation (E333D) in the thyroid hormone beta receptor causing resistance to thyroid hormone syndrome." ], "offsets": [ [ 0, 109 ] ] }, { "id": "521", "type": "abstract", "text": [ "Resi...
[ { "id": "513", "type": "ProteinMutation", "text": [ "E333D" ], "offsets": [ [ 18, 23 ] ], "normalized": [] }, { "id": "514", "type": "ProteinMutation", "text": [ "E333D" ], "offsets": [ [ 497, 502 ...
[]
[]
[]
522
17065479
[ { "id": "523", "type": "title", "text": [ "Homozygous deletion related to Alu repeats in RLBP1 causes retinitis punctata albescens." ], "offsets": [ [ 0, 88 ] ] }, { "id": "524", "type": "abstract", "text": [ "PURPOSE: Retinitis punctat...
[]
[]
[]
[]
525
17065190
[ { "id": "534", "type": "title", "text": [ "Monocyte chemotactic protein-1 single nucleotide polymorphisms do not confer susceptibility for the development of adult onset polymyositis/dermatomyositis in UK Caucasians." ], "offsets": [ [ 0, 173 ] ] }, { ...
[ { "id": "526", "type": "SNP", "text": [ "rs2857657" ], "offsets": [ [ 924, 933 ] ], "normalized": [] }, { "id": "527", "type": "DNAMutation", "text": [ "C/G" ], "offsets": [ [ 935, 938 ] ], ...
[]
[]
[]