| { |
| "cohort": { |
| "n_genomes": 120, |
| "n_defense_subtypes": 163, |
| "n_lineage_clusters": 50, |
| "median_cluster_size": 1.0, |
| "mean_chromosomal_systems": 13.208333333333334, |
| "sd_chromosomal_systems": 4.636622034292734, |
| "crispr_columns_found": [ |
| "CAS_Class1-Subtype-I-C", |
| "CAS_Class1-Subtype-I-E", |
| "CAS_Class1-Subtype-I-F", |
| "Rst_HelicaseDUF2290" |
| ], |
| "frac_genomes_with_crispr": 0.5166666666666667, |
| "n_exposure_covariates": 21 |
| }, |
| "testA_all_defense_load": { |
| "partial_r2": 0.5269544014510156, |
| "null_mean_r2": 0.4320713085651996, |
| "partial_r2_excess": 0.09488309288581598, |
| "pvalue": 0.14770459081836326, |
| "n": 120, |
| "n_covariates_used": 21 |
| }, |
| "testA_crispr_only": { |
| "partial_r2": 0.6165075616763955, |
| "null_mean_r2": 0.3320706409474731, |
| "partial_r2_excess": 0.28443692072892246, |
| "pvalue": 0.007984031936127744, |
| "n": 120, |
| "n_covariates_used": 21 |
| }, |
| "testB_load_vs_extrachrom_len": { |
| "spearman": -0.0618653189512368, |
| "pvalue": 0.5020609247195801, |
| "n": 120 |
| }, |
| "testB_load_vs_extrachrom_systems": { |
| "spearman": -0.13813354433360708, |
| "pvalue": 0.13243690866017466, |
| "n": 120 |
| }, |
| "testB_crispr_vs_extrachrom_len": { |
| "spearman": 0.19120821884001532, |
| "pvalue": 0.03643852052574965, |
| "n": 120 |
| }, |
| "per_system": { |
| "n_tested": 19, |
| "n_significant_p05": 4, |
| "frac_significant": 0.21052631578947367, |
| "median_partial_r2": 0.45165904520189054, |
| "max_partial_r2": 0.7051780095912905, |
| "worst_systems": [ |
| { |
| "system": "RloC", |
| "partial_r2": 0.7051780095912905, |
| "pvalue": 0.0024937655860349127 |
| }, |
| { |
| "system": "Zorya_TypeI", |
| "partial_r2": 0.6426652297210771, |
| "pvalue": 0.0798004987531172 |
| }, |
| { |
| "system": "Gabija", |
| "partial_r2": 0.6293146894559207, |
| "pvalue": 0.0024937655860349127 |
| }, |
| { |
| "system": "N6_RM_Type_I", |
| "partial_r2": 0.5825399986303417, |
| "pvalue": 0.004987531172069825 |
| }, |
| { |
| "system": "GmrSD_RM_Type_IV", |
| "partial_r2": 0.5769292825344523, |
| "pvalue": 0.014962593516209476 |
| } |
| ] |
| } |
| } |
