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  "cohort": {
    "n_genomes": 1200,
    "n_defense_subtypes": 236,
    "n_lineage_clusters": 184,
    "median_cluster_size": 2.0,
    "mean_chromosomal_systems": 12.339166666666667,
    "sd_chromosomal_systems": 4.997579344598298,
    "crispr_columns_found": [
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      "CAS_Class1-Type-I",
      "Rst_HelicaseDUF2290"
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    "frac_genomes_with_crispr": 0.5358333333333334,
    "n_exposure_covariates": 21
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  "testA_all_defense_load": {
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    "n_covariates_used": 21
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  "testA_crispr_only": {
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    "n_covariates_used": 21
  },
  "testB_load_vs_extrachrom_len": {
    "spearman": 0.15346876727421646,
    "pvalue": 9.169772191035603e-08,
    "n": 1200
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  "testB_load_vs_extrachrom_systems": {
    "spearman": 0.08176611321456927,
    "pvalue": 0.004593249117499305,
    "n": 1200
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  "testB_crispr_vs_extrachrom_len": {
    "spearman": -0.08849996099142415,
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  "per_system": {
    "n_tested": 116,
    "n_significant_p05_uncorrected": 73,
    "n_expected_by_chance_p05": 5.800000000000001,
    "n_significant_BH_q10": 79,
    "frac_significant_BH_q10": 0.6810344827586207,
    "median_partial_r2": 0.049194222796417164,
    "max_partial_r2": 0.3668275957603121,
    "worst_systems": [
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        "system": "BREX_II",
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        "system": "RnlAB",
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}