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  "cohort": {
    "n_genomes": 1200,
    "n_defense_subtypes": 236,
    "n_lineage_clusters": 344,
    "median_cluster_size": 2.0,
    "mean_chromosomal_systems": 12.339166666666667,
    "sd_chromosomal_systems": 4.997579344598298,
    "crispr_columns_found": [
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      "CAS_Class1-Subtype-I-F",
      "CAS_Class1-Type-I",
      "Rst_HelicaseDUF2290"
    ],
    "frac_genomes_with_crispr": 0.5358333333333334,
    "n_exposure_covariates": 21
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  "testA_all_defense_load": {
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    "partial_r2_excess": 0.030989674444405927,
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    "n": 1200,
    "n_covariates_used": 21
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  "testA_crispr_only": {
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  },
  "testB_load_vs_extrachrom_len": {
    "spearman": 0.08194888875640106,
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    "n": 1200
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  "testB_load_vs_extrachrom_systems": {
    "spearman": 0.0799184824601281,
    "pvalue": 0.0056055638081669076,
    "n": 1200
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  "testB_crispr_vs_extrachrom_len": {
    "spearman": 0.022771070421412815,
    "pvalue": 0.43064223490652587,
    "n": 1200
  },
  "per_system": {
    "n_tested": 116,
    "n_significant_p05_uncorrected": 65,
    "n_expected_by_chance_p05": 5.800000000000001,
    "n_significant_BH_q10": 70,
    "frac_significant_BH_q10": 0.603448275862069,
    "median_partial_r2": 0.057970795306195144,
    "max_partial_r2": 0.32909252763754515,
    "worst_systems": [
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        "system": "Rst_3HP",
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        "pvalue_bh": 0.00997506234413965
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      {
        "system": "CBASS_II_HNH",
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      {
        "system": "Lamassu_HNH",
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}