Datasets:
ccdv
/
pubmed-summarization

Dataset card Data Studio Files
xet
 Community
8
article
stringlengths
0
826k
abstract
stringlengths
174
4.34k
schwannoma is a benign nerve sheath tumor that most commonly occurs solitary in otherwise normal individuals . occasionally it presents with multiple form involving several areas along the peripheral nervous system , including cranial nerves , spinal nerve roots , the brachial and lumbosacral plexuses , or major peri...
schwannomatosis or neurilemmomatosis has been used to describe patients with multiple nonvestibular schwannomas with no other stigmata of neurofibromatosis type-2 ( nf-2 ) . in our case , schwannomatosis , multiple schwannomas were present in a 21-yr - old woman with no stigmata or family history of nf-1 or nf-2 . ...
rna interference ( rnai ) has opened new avenues for the systematic analysis of phenotypes . with the completion of many whole genome sequences , rnai allows the depletion of gene products in a wide range of organisms , thus enabling reverse genetic approaches where genetic tools are lacking . the molecular mechani...
rna interference ( rnai ) has emerged as a powerful tool to generate loss - of - function phenotypes in a variety of organisms . combined with the sequence information of almost completely annotated genomes , rnai technologies have opened new avenues to conduct systematic genetic screens for every annotated gene in t...
it has been reported that the lack of insight is prevalent among patients with schizophrenia and that impaired insight is significantly associated with medication noncompliance , frequent relapse , and poor prognosis.15 insight in mental illness is generally a multidimensional concept that includes the following aspect...
backgroundthe concept of cognitive insight refers to the cognitive processes involved in patients re - evaluation of their anomalous experiences and of their misinterpretations . the purpose of the present study was to examine the relationship between cognitive insight and subjective quality of life in patients with ...
brucellosis is one of the world 's major bacterial zoonosis and an important cause of a serious debilitating disease in humans ; further , it is the cause of abortion and sterility in animals . brucella canis , a facultative , gram - negative , intracellular pathogen , is the etiologic agent of canine brucellosis . ...
brucella canis , a facultative intracellular pathogen , is the causative agent of canine brucellosis . the diagnosis of canine brucellosis is based on bacteriological examination and serological methods , including agglutination and gel diffusion tests . in this study , four recombinant antigens , heat shock protein ...
to characterize hcv - specific cd8 t cell mediated responses associated with severe liver pathology in acute hcv infection , we analyzed the global profile of the hcv - specific t cell response in eight patients who showed variable outcomes of acute hcv infection ( fig . 1 a , patients 1 and 2 ) that were infected w...
hepatitis c virus ( hcv ) can cause liver disease of variable severity . expansion of preexisting memory cd8 t cells by cross - reactivity with a new heterologous virus infection has been shown in mice to shape the repertoire of the primary response and to influence virus - related immunopathology ( selin , l.k . 2...
naja sumatrana , commonly known as the black spitting cobra or equatorial spitting cobra , is the dominant cobra species in peninsular malaysia , singapore , borneo , and sumatra . it was estimated that the highest burden of snake bites exists in south asia , southeast asia , and sub - saharan africa . cobra bites ...
naja sumatrana is the dominant cobra species in malaysia , singapore , borneo , and sumatra , and it does not have specific antivenom . the haffkine antivenom has been advocated instead . this study aims to determine the efficacy of this antivenom against naja sumatrana envenoming using a mouse model . methods . ...
the setting was the kaiser permanente medical care program of northern california ( kpnc ) , a large group practice prepaid health plan where gdm is diagnosed in accordance with the american diabetes association ( ada ) guidelines ( 2,13 ) . the study was conducted in collaboration with the kpnc regional perinatal se...
objectiveto pilot , among women with gestational diabetes mellitus ( gdm ) , the feasibility of a prenatal / postpartum intervention to modify diet and physical activity similar to the diabetes prevention program . the intervention was delivered by telephone , and support for breastfeeding was addressed.research desi...
florid cemento - osseous dysplasia ( fcod ) refers to a group of fibro - osseous lesions , which are exuberant , multiquadrant and arise from the tooth - bearing area of the jaws . fcod is a benign jaw lesion and is discovered most frequently in the mandible of middle - aged black female . it usually presents...
abstractbackgroundthe purpose of this report is to present a rare case of co - occurrence of florid cemento - osseous dysplasia with simple bone cyst in a middle aged asian woman . most of the reported cases are isolated cases of simple bone cyst or florid cemento - osseous dysplasia , but co - occurrence of th...
gaucher disease ( gd ) is an autosomal recessive lysosomal glycolipid storage disorder characterized by the accumulation of glucocerebroside ( glucosylceramide ) in reticuloendothelial cells . the gene coding for the deficient enzyme glucocerebrosidase ( acid beta - glucosidase ) is located on chromosome 1q21 .three ...
in gaucher disease ( gd ) the enzyme ( imiglucerase ) replacement therapy ( ert ) is not able to stop the progression of the neurological involvement , while the substrate reduction therapy ( srt ) , performed by n - butyldeoxynojirimycin ( miglustat ) , is an alternative that should be evaluated . two sisters , pres...
up to 10% of newborn infants require admission to the neonatal intensive care unit ( nicu ) for ongoing medical care [ 13 ] . antibiotic administration is known to perturb the composition of the intestinal microbiota , resulting in suppression of anaerobic bacteria ( with the exception of clostridia , which remain at...
we investigated the impact of parenteral antibiotic treatment in the early neonatal period on the evolution of bifidobacteria in the newborn . nine babies treated with intravenous ampicillin / gentamicin in the first week of life and nine controls ( no antibiotic treatment ) were studied . denaturing gradient gel e...
night blindness is a visual disorder associated with visual disturbance during the night or in darkness . in addition , patients with night blindness need more time for accommodation when the lucency of an environment is decreased . night blindness occurs in response to a decrease in rhodopsin in retinal light - sens...
background : night blindness is a visual disorder associated with unusual vision during the night or in darkness . vitamin a deficiency ( vad ) , which is easily preventable , is the main known etiology of night blindness . malnutrition is a common health issue in bashagard and some other areas in the hormozgan provi...
here we have reviewed the conventional definitions and fundamental characteristics of the two basic types of stem cells , embryonic stem cells ( escs ) and somatic stem cells ( sscs ) . by taking into account the often - overlooked asymmetric cell kinetics of sscs , we consider the evidence that should sscs retain th...
abstracthere we have reviewed the conventional definitions and fundamental characteristics of the two basic types of stem cells , embryonic stem cells ( escs ) and somatic stem cells ( sscs ) . by taking into account the often - overlooked asymmetric cell kinetics of sscs , we consider the evidence that should sscs r...
horner 's syndrome , along with weakness and atrophy of upper limb , as well as anaesthesia to pain and temperature , is well recognized finding in patients with syringomyelia . few cases have been reported regarding isolated horner 's syndrome as a presenting manifestation of a chiari i malformation with syringomyel...
we present a 41-year - old man with chiari type 1 malformation and syrinx up to tenth thoracic level who presented with left side hemi anhidrosis . neurological findings of syrinx were absent in this case . though horner 's syndrome is reported , this report is probably first .
oxcarbazepine ( oxc ) , ( chemically known as 10,11-dihydro-10-oxo-5h - dibenzo[b , f]azepine-5-carboxamide ) , is a novel antiepileptic drug , which was developed as a second generation and a follow - up compound to carbamazepine . clinically , it has been used to treat several types of epilepsy [ 13 ] and bipolar d...
titrimetric and spectrophotometric methods are described for the determination of oxcarbazepine ( oxc ) in bulk drug and in tablets . the methods use n - bromosuccinimide ( nbs ) and bromopyrogallol red ( bpr ) as reagents . in titrimetry ( method a ) , an acidified solution of oxc is titrated directly with nbs usi...
life in the ocean is dependent on fixation of carbon ( c ) and nitrogen ( n ) by planktonic microalgae , ranging in diameter from < 1 to > 100 m . these phytoplankton consist of eukaryotic algae , which photosynthetically fix carbon dioxide ( co2 ) into organic matter , and cyanobacteria that fix co2 and also fix ...
in addition to control by major nutrient elements ( nitrogen , phosphorus , and silicon ) the productivity and species composition of marine phytoplankton communities are also regulated by a number of trace metal nutrients ( iron , zinc , cobalt , manganese , copper , and cadmium ) . of these , iron is most limiting to...
the human immunodeficiency virus ( hiv ) infection is a global pandemic , with cases reported from virtually every country . at the end of 2010 , an estimated 34 million people were living with hiv globally , including 3.4 million children less than 15 years . in 2010 , an estimated 250 000 children less than 15 y...
microalbuminuria has been reported to be a precursor of hiv related renal disease , which if detected early and coupled with appropriate intervention may slow or retard the progress of the disease . one hundred and seventy - eight hiv infected children aged 15 years and below were recruited from the paediatric infect...
lymphoma , malign melanoma and rhabdomyosarcoma are the most common tumors that metastasize to the breast tissue . breast metastases in cases of leukemia are very rare and occur primarily in patients with acute myeloid leukemia . we report the conventional and advanced magnetic resonance imaging ( mri ) findings of...
breast metastases in cases of leukemia are rare . we aimed to report the conventional - advanced magnetic resonance imaging ( mri ) findings of unilateral breast involvement of acute lymphoblastic leukemia ( all ) and review the literature . a 32-year - old woman was first diagnosed with all in treated in 2004 . sh...
. advanced laparoscopic procedures are increasingly being utilized as an alternative for laparotomy in gynecologic surgery . a metaanalysis of 27 prospective randomized trials has proven the benefits of laparoscopic - assisted vaginal hysterectomy ( lavh ) compared with abdominal hysterectomy ( ah ) : decreased pain ...
introduction : prospective randomized trials have proven the benefits of laparoscopic - assisted vaginal hysterectomy ( lavh ) compared with abdominal hysterectomy . the purpose of this study was to evaluate the safety and efficacy of lavh performed for uteri weighing 1000 grams.methods:fifteen patients underwent attem...
the data deluge brought about by the genomic projects has fostered an unprecedented level of expectation for new medical , pharmacological , environmental and biotechnological discoveries . proteins mediate the majority of the functions of an organism , and all these functions are , by and large , determined by the p...
the protein model database ( pmdb ) is a public resource aimed at storing manually built 3d models of proteins . the database is designed to provide access to models published in the scientific literature , together with validating experimental data . it is a relational database and it currently contains > 74 000 ...
autophagy is induced downstream of signaling by danger receptors including toll like receptors ( tlr ; xu et al . , 2007 ; delgado et al . , 2008 ) , retinoic acid inducible gene i - like receptors ( rlr ; yano et al . , 2008 ; cooney et al . , 2010 ; travassos et al . , xenophagy describes the process by which ...
macroautophagy ( autophagy ) is a cellular pathway facilitating several critical functions . first , autophagy is a major pathway of degradation . it enables elimination of microbes that have invaded intracellular compartments . in addition , it promotes degradation of damaged cellular content , thereby acting to...
in response to a dynamic nutrient environment , cells must assess their metabolic state to decide whether to grow , survive , or die . it has become evident that metabolites themselves must feed back to regulate gene expression , signal transduction , and various protein activities in cellular decision - making proce...
acetyl - coa represents a key node in metabolism due to its intersection with many metabolic pathways and transformations . emerging evidence reveals that cells monitor the levels of acetyl - coa as a key indicator of their metabolic state , through distinctive protein acetylation modifications dependent on this meta...
the importance of evidence - based practice ( ebp ) in allied health is well documented in the literature.1,2 clinical decisions that are based on patients unique circumstances , sound clinical expertise , and the best available research evidence are known to deliver the best outcomes for patients and their families.35...
purposethe current versions of the adapted fresno test ( aft ) are limited to physiotherapists and occupational therapists , and new scenarios and scoring rubrics are required for other allied health disciplines . the aim of this study was to examine the validity , reliability , and internal consistency of the aft de...
embryonic development and later rejuvenation of adult tissue is regulated by a population of stem cells that , by undergoing self - renewal maintain their own pool and give rise to differentiated progenitors that replace cells used up during the life cycle ( 1 ) . therefore , scs are guardians of tissue / organ integ...
pluripotent stem cells ( pscs ) have been considered as the most important cells in regenerative medicine as they are able to differentiate into all types of cells in the human body . pscs have been established from several sources of embryo tissue or by reprogramming of terminally differentiated adult tissue by tran...
abnormal involuntary movements may appear in any part of the body , and can be embarrassing , distressing , disfiguring or dangerous . tremor is an involuntary rhythmic oscillation of one or more parts of body about a fixed plane in space . tremors are observed with the use of various drugs , including tricyclic an...
identification and management of drug - induced movement disorders is a clinical challenge , more so when the clinical presentation is atypical . a young male with acute mania was under treatment with sodium valproate and risperidone . he developed tremors of right hand and neck . these were present at rest and e...
lobular carcinoma in situ ( lcis ) is a form of in situ neoplasia that develops within the terminal lobules of the breast . it is extremely rare in males due to the lack of lobular development in the male breast . furthermore , there is scarce data on the utility of screening mri for male patients who are known to ...
lobular carcinoma in situ is a form of in situ neoplasia that develops within the terminal lobules of the breast . it is an extremely rare finding in males due to the lack of lobular development in the male breast . the authors herein report an unusual case of incidentally discovered lobular carcinoma in situ in a ...
obesity has been considered as a general health problem around the world . in the united states , the prevalence of obesity is 35.5% among men and 35.8% among women and in iran it has been reported 42.9% among men and 56.9% among women . obesity is related to increased risk of hyper - tension , diabetes mellitus , ...
background : obesity is a common health problem around the world . studies have shown inverse relationship between serum vitamin d levels with obesity among patients and healthy population . the aim of this present study is to examine the relationship between serum vitamin d levels with general and abdominal obesit...
refractory ascites can occur in patients with conditions such as liver cirrhosis , congestive heart failure , nephrotic syndrome , and lupus serositis1 and in many cases cause abdominal discomfort and respiratory distress to the patient . the treatments for refractory ascites , eg , bed rest , salt and water restrict...
refractory ascites can occur in patients with various conditions . although several procedures based on the reinfusion of ascitic fluid have been reported after the failure of bed rest , salt and water restriction , diuretics , intravenous administration of albumin , and repeated paracentesis , these procedures are p...
the behavior of oral health providers and their attitudes towards their own oral health reflect their understanding of the importance of preventive dental procedures and improving the oral health of their patients . also , dental students should instruct their friends , family members , patients and their society to ...
objectivesthe purpose of this study was to evaluate self - reported oral health attitude and behavior among a group of turkish dental students and to compare differences in oral health attitudes between years of study and gender.methodsthis study included 267 ( 153 female , 114 male ) dental students . a modified engli...
treacher collins syndrome ( tcs ) is a severe congenital disorder of craniofacial development characterized by numerous developmental anomalies that are restricted to the head and face . hypoplasia of the facial bones , particularly the mandible and zygomatic complex , is an extremely common feature of tcs . althou...
franceschetti syndrome is an autosomal dominant disorder of craniofacial development with variable expressivity . it is commonly known as treacher collins syndrome ( tcs ) . it is named after e. treacher collins who described the essential components of the condition . it affects both genders equally . this art...
type 2 diabetes mellitus ( t2 dm ) is a progressive disease where hyperglycemia occurs when insulin secretion fails to keep pace with insulin resistance.1 therefore , long - term disease management warrants intensification of treatment over time , especially in step with declining beta - cell function.2 in general , t2...
type 2 diabetes mellitus ( t2 dm ) is a progressive disease warranting intensification of treatment , as beta - cell function declines over time . current treatment algorithms recommend metformin as the first - line agent , while advocating the addition of either basal - bolus or premixed insulin as the final level o...
literature was searched in the medline database , using the following criteria : human epididymis protein 4 ( he4 ) , ovarian carcinoma , ca125 ; and screening or diagnosis or prognosis or monitoring ; and ovarian carcinoma or he4 or human epididymis protein 4 , or ca125 . filters are publication dates from january 1...
objectiveto present an update of the european group on tumor markers guidelines for serum markers in epithelial ovarian cancer.methodssystematic literature survey from 2008 to 2013 . the articles were evaluated by level of evidence and strength of recommendation.resultsbecause of its low sensitivity ( 5062% for early...
recombinant atxa , atnl and its quadruple h28y / l31v / n33g / s49d mutant lw were prepared by in vitro refolding following expression in e. coli as described . all other chemicals were from sigma aldrich or gibco life technologies . adult male balb / c mice ( 2025 g ) were maintained and humanely killed according to...
the molecular mechanism of action of presynaptically neurotoxic secreted phospholipases a2 ( spla2s ) has not been fully elucidated . we have recently proposed a model to explain one of the hallmarks of their action the reduction in endocytosis leading to synaptic vesicle depletion in nerve terminals . our results...
porphyromonas gingivalis is a gram - negative oral anaerobe that is involved in the pathogenesis of periodontitis , an inflammatory disease that destroys the tissues supporting the tooth which eventually may lead to tooth loss . among the over 500 bacterial species living in the oral cavity , a bacterial complex name...
porphyromonas gingivalis is a gram - negative oral anaerobe that is involved in the pathogenesis of periodontitis and is a member of more than 500 bacterial species that live in the oral cavity . this anaerobic bacterium is a natural member of the oral microbiome , yet it can become highly destructive ( termed pathob...
bipolar disorders ( bd ) are of particular public health significance as they are prevalent , severe and disabling , and often associated with elevated risks of premature mortality , adverse medical outcomes , accidents , and complications from comorbid substance use disorders.1 the world health organization reported ,...
background : bipolar disorders ( bd ) are of particular public health significance as they are prevalent , severe and disabling , and often associated with elevated risks of premature mortality . the aim of this concise overview is to investigate the role of asenapine in the treatment of manic and mixed states associ...
a 3-month - old girl child presented to us with a history of swelling on back since birth . she had a history of full term normal vaginal delivery with no significant family history . there was complete flaccid paralysis of right lower extremity with normal anal tone . on local examination , an initial diagnosis ...
variations in split cord malformation ( scm ) have been described earlier . however , a true hemimyelomeningocele ( hmm ) as only congenital malformation is extremely rare and is reported infrequently in published literature . we are reporting the case of a 3-month - old girl child who presented with a swelling on th...
interact is a large , prospective , case - cohort study of 27,779 individuals from eight european countries ( denmark , france , germany , italy , the netherlands , spain , sweden , and u.k . ) nested within the european prospective investigation into cancer and nutrition ( epic ) ( 20 ) . the objective of the study ...
objectiveyounger age at menarche , a marker of pubertal timing in girls , is associated with higher risk of later type 2 diabetes . we aimed to confirm this association and to examine whether it is explained by adiposity.research design and methodsthe prospective european prospective investigation into cancer and nut...
cigarette butts and other tobacco product waste ( tpw ) items are the most ubiquitous form of litter worldwide , with an estimated 4.5 trillion of the estimated annual 6 trillion globally consumed cigarettes deposited as butts somewhere into the environment each year . this material comprises the largest percentage o...
cigarette butts and other tobacco product wastes ( tpw ) are the most common items picked up in urban and beach cleanups worldwide . tpw contains all the toxins , nicotine , and carcinogens found in tobacco products , along with the plastic nonbiodegradable filter attached to almost all cigarettes sold in the united ...
astasia is a clinical postural disorder characterized by the inability to stand without external support despite having sufficient muscle strength . this symptom can be observed in post - stroke patients who have experienced thalamic hemorrhage or ischemia1,2,3 , and it is frequently accompanied by falling towa...
[ purpose ] post - stroke astasia is an inability to stand without external support despite having sufficient muscle strength . however , the dysfunction underlying astasia is unclear . we tested the hypothesis that astasia is the result of an abnormal bias in vertical perception , especially subjective postura...
a 34-year - old male presented with proptosis of the left eye ( os ) in november 2014 since 2 years with occasional pain and blurred vision . best - corrected visual acuity was 6/6 , n6 right eye ( od ) , 6/18 with pinhole improvement to 6/9 , n10 ( os ) . axial proptosis was noted with hertel 's exophthalmometry m...
cavernous hemangioma is the most common orbital tumor in adult . there is lot of literatures for clinicopathological features of this tumor . these tumors had been studied for the model of angiogenesis in many of the experimental setups . we present a case of 34-year - old male with this tumor in the left eye wit...
the prevalence of placenta previa has been recently estimated to be approximately 0.5% of all pregnancies , and this increase correlates to the elevated cesarean section rate1 . placenta previa is a major cause of maternal morbidity and mortality because of the associated massive antepartum and intrapartum hemorrhage...
purpose : to evaluate whether type and location of placenta previa affect risk of antepartum hemorrhage - related preterm delivery . methods : we retrospectively studied 162 women with singleton pregnancies presenting placenta previa . through observation using transvaginal ultrasound the women were categorized int...
edcs are chemicals that interfere with the biosynthesis , metabolism , or action of endogenous hormones resulting in deviation from normal developmental programming and reproductive function . the male sexual differentiation is entirely androgen - dependent and therefore highly susceptible to edcs that disrupt androg...
endocrine disruptive chemicals ( edcs ) modulate hormone signaling and cause developmental and reproductive anomalies . today , there is a global concern regarding endocrine disruption effects , particularly those mediated by the androgen receptor ( ar ) . androgen or male hormones are critical for the development ...
myostatin , encoded by the mstn gene ( previously referred to as gdf8 ) , is a member of the transforming growth factor superfamily that normally acts to limit skeletal muscle mass by regulating both the number and growth of muscle fibres [ 1 , 2 ] . mstn is synthesized as precursor and upon proteolytic processing g...
myostatin ( mstn ) is a negative modulator of muscle mass . we characterized the horse ( equus caballus ) mstn gene and identified and analysed single nucleotide polymorphisms ( snps ) in breeds of different morphological types . sequencing of coding , untranslated , intronic , and regulatory regions of mstn gene i...
small cell lung cancer ( sclc ) represents 1320% of all new lung cancer diagnoses . it is the most aggressive histological subtype of lung cancer , with a strong predilection for early metastases . the brain is a common site of metastasis in sclc . at the initial diagnosis , at least 10% of the patients with sclc...
small cell lung cancer is characterized by rapid growth and early metastasis . despite its sensitivity to cytotoxic therapy , until now treatments have failed to control or cure this disease in most patients . orbital metastases are a rare manifestation of systemic malignancies . breast and lung cancers represent m...
in partnership with the government of bangladesh , the us centers for disease control and prevention ( cdc ) and the international centre for diarrhoeal disease research , bangladesh ( icddr , b ) established nationwide hospital - based surveillance to identify clusters of persons with life - threatening influenza viru...
we identified avian influenza virus a ( h5n1 ) infection in a child in bangladesh in 2008 by routine influenza surveillance . the virus was of the same clade and phylogenetic subgroup as that circulating among poultry during the period . this case illustrates the value of routine surveillance for detection of novel...
it is estimated that 4% to 7% of adults in the unites states have palpable nodules upon examination . with the advent of ultrasonographic ( us ) techniques for assessment of the thyroid gland , it is now believed that a nodule can be detected in as many as 67% of the normal population . the first and foremost obsta...
purpose . we sought to investigate the utility of classification and regression trees ( cart ) classifier to differentiate benign from malignant nodules in patients referred for thyroid surgery . methods . clinical and demographic data of 271 patients referred to the sadoughi hospital during 20062011 were collected...
tullus et al . recently published an algorithm for the orderly investigation of renovascular hypertension in children , in which ultrasonography is one of the primary studies . doppler ultrasound non - invasively assesses renal artery flow , but is less sensitive than angiography . computed tomographic ( ct ) ang...
standard initial assessment via ultrasound of a 4-year - old girl with hypertension revealed the absence of one kidney . instead of cross - sectional imaging of the retroperitoneal space , a functional ( nuclear ) study was performed . this revealed a malformed kidney within the chest . though systemic levels of re...
the spectrum of age - related , ebv - positive lymphoproliferative disorders ( aebvlpd ) was first described by oyama and coworkers and distinctively occurs in elderly patients without any history of immunosuppression 1 . further analysis of aebvlpd cases revealed a heterogeneous group of diseases with very different...
key clinical messagethe oral manifestations of ebv - positive mucocutaneous ulcers have a worrisome clinical appearance but relatively benign clinical course , responding well to conservative treatment . elderly patients who develop an unexplained , persistent ulcer of the oral mucosa should have the lesion examined ...
intracranial germ cell tumors ( gcts ) are rare neoplasms that typically arise in the pineal and suprasellar regions . they account for 0.5 - 3% of all pediatric tumors of the central nervous system ( cns ) , germinomas being the most common histological type . although the production of tumor - associated human ch...
this study aims to report a rare case of precocious puberty ( pp ) due to a human chorionic gonadotropin ( hcg)-producing germinoma located in the suprasellar region . a 10-year - old male patient presented with sexual precocity , headache , drowsiness , loss of appetite , and papilledema . significant acceleration o...
bacterial , parasitic , viral infections and almost all of the immunosuppressive drugs used can produce diarrhea ; however , inflammatory bowel disease ( ibd ) is rare in the transplant recipient . a 46-year - old man who developed end - stage renal disease ( esrd ) of unknown etiology underwent live related renal tr...
diarrhea is common after kidney transplantation and is usually related to immunosuppressive medication or is infective in etiology . inflammatory bowel disease ( ibd ) is rare after kidney transplantation and is unexpected because the patient is already immunosuppressed . specific immunomodulatory actions of calcin...
the increasingly expanding biomedical and biophysical research areas trace back to the human genome project ( hgp ) founded and started in 1990 as a manhood 's big challenge for providing scientific findings to better understand biochemistry , molecular biology and medical sciences 1 . in the year 2001 the human 's g...
the personalized medicine , also documented as individualized medicine , is an effective and therapeutic approach . it is designed to treat the disease of the individual patient whose precise differential gene expression profile is well known . the trend in the biomedical and biophysical research shows important ...
recent technological advances allow the rapid generation of vast quantities of molecular biological data . at the same time , the sequencing of the human genome and subsequent efforts to catalogue the variation within it have created opportunities for testing thousands of sequence variations for association with diseas...
recent developments in the statistical analysis of genome - wide studies are reviewed . genome - wide analyses are becoming increasingly common in areas such as scans for disease - associated markers and gene expression profiling . the data generated by these studies present new problems for statistical analysis , ...
asbestos causes lung fibrosis known as asbestosis , a few benign pleural diseases such as pleural plaque and effusion , and malignant diseases such as mesothelioma and lung cancers [ 15 ] . furthermore , cancers in other organs such as the gastrointestinal tract , larynx , kidney , liver , pancreas , ovary , and hema...
asbestos causes lung fibrosis known as asbestosis as well as cancers such as malignant mesothelioma and lung cancer . asbestos is a mineral silicate containing iron , magnesium , and calcium with a core of sio2 . the immunological effect of silica , sio2 , involves the dysregulation of autoimmunity because of the c...
this condition was defined by the international elbow working group ( iewg ) in 1993 to include fragmented medial coronoid process ( fmcp ) , osteochondrosis of the humerus ( oc ) , ununited anconeal process ( uap ) , articular cartilage injury , and incongruity of the elbow joint . these disorders are associated wit...
one hundred and five labrador dogs were randomly divided into two groups to determine the number of animals that develop elbow dysplasia when treated with an oral supplement compared to untreated ones . efficacy of the oral treatment was also evaluated once illness was diagnosed . the supplement ( hyaloral ) contai...
primary biliary cirrhosis ( pbc ) is an autoimmune disease in which the intrahepatic bile ducts are targeted by an immunemediated injury . pbc is associated with a range of conditions , including sjgren 's syndrome in 70% of patients 2 , autoimmune thyroid disease in approximately 10% , and systemic sclerosis in 15% ...
key clinical messagethe true prevalence of pbc in ra is not well known . herein , we report an unusual case of a patient with pbc and ra , and discuss the association between these two diseases . pbc should be ruled out in the differential diagnosis of patients with ra having abnormal liver function tests .
exercise - induced bronchoconstriction ( eib ) , also referred to as exercise - induced asthma ( eia ) , is a manifestation of bronchial hyperresponsiveness ( bhr ) that occurs in the majority of patients with current symptomatic asthma , especially in the patients with moderately to severely increased responsiveness [...
in order to assess prevalence and characteristics of exercise - induced respiratory symptoms ( eirss ) and exercise - induced bronchoconstriction ( eib ) in health care workers , we performed a cross - sectional study including 48 female nurses from primary care settings and an equal number of female office worke...
a 74-year - old man presented with mild dyspnea and chest discomfort for 30 months . trans - thoracic echocardiographic findings showed a left atrial echogenic mass ( 21.5 cm ) ( fig . 1 ) . a provisional diagnosis of a left atrial ( la ) myxoma was made , and the patient was admitted for the surgical excision of t...
hemangioma of the heart , presenting as a primary cardiac tumor is extremely rare ; it accounts for approximately 2% of all primary resected heart tumors . in our patient , the tumor was located in the orifice of the right lower pulmonary vein . few cases of cardiac hemangiomas have been reported to arise from the ...
blunt trauma of the abdominal wall can lead to a traumatic abdominal wall hernia ( tawh ) . defined tawh as the herniation through disrupted musculature and fascia associated with adequate trauma , without skin penetration , and no evidence of a prior hernia defect at the site of injury . although this type of he...
although blunt abdominal trauma is frequent , traumatic abdominal wall hernias ( tawh ) are rare . we describe a large tawh with associated intra - abdominal lesions that were caused by high - energy trauma . the diagnosis was missed by clinical examination but was subsequently revealed by a computed tomography ( c...
the online version of this article ( doi:10.1007/s00417 - 011 - 1700 - 2 ) contains supplementary material , which is available to authorized users . silicone intubation of the lacrimal system has become very popular in the treatment of congenital nasolacrimal duct obstructions ( cnldo ) resistant to conservative the...
backgroundto compare the success rate of monocanalicular intubation ( mci ) compared with bicanalicular silicone intubation ( bci ) in congenital nasolacrimal duct obstruction ( cnldo ) in infants and toddlers.methodsin a prospective , nonrandomized , comparative study , mci ( n = 35 eyes ) through the inferior can...
it is the most common surgical operation throughout the world , and is one of the most common rituals in jewish and islamic cultures . most circumcisions are performed for religious reasons as in islamic countries and few are performed for medical reasons . although circumcision is considered to be a technically si...
penile amputation is a rare catastrophe and a serious complication of circumcision . reconstruction of the glans penis may be indicated following amputation . our report discusses a novel technique for reconfiguration of an amputated glans penis 1 year after a complicated circumcision . a 2-year - old male infant p...
they have significant effect on the synthesis , mobilization , and metabolism of lipids and lipoproteins . dyslipidemia is a common metabolic abnormality in patients with thyroid disease , in either the overt or the subclinical forms of the disease . it has been known that overt hypothyroidism is associated with pr...
objective . the risk of atherosclerotic heart disease is increased in autoimmune thyroiditis , although the reason is not clear . lipoprotein(a ) ( lp(a ) ) excess has been identified as a powerful predictor of premature atherosclerotic vascular diseases . the aim of this study is to investigate the relationship ...
parathyroid carcinoma is the least common endocrine malignancy , and accounted for only 0.005% of cases reported to the national cancer database ( ncdb ) between 1985 and 1995 . roughly half of cases are diagnosed between ages 45 and 60 years , but the tumor arises over a wide age range . in the ncdb case series , o...
parathyroid carcinoma is a rare malignancy , and only accounts for 0.52% of cases of primary hyperparathyroidism . less than 10% of parathyroid carcinomas are non - functional , and as such , they have been rarely reported in the literature . importantly , margin status at resection is related to prognosis , and on...
furthermore , these molecules are involved in modulation of adhesion processes at the endothelium and thus promote the transendothelial migration of leukocytes ( haptotaxis ) . in addition , some chemokines stimulate angiogenesis or angiostasis and thus may play a further role in the suppression of tumor growth or th...
efficient recruitment and activation of immuno - competent cells is crucial for an effective immune response to hepatitis c virus ( hcv ) infection . chemokines and chemokine receptors have been shown to be critically involved in these processes.the ccr5 chemokine receptor is expressed on several cells of the immune ...
echinococcosis in an important parasitic infection that is still a common health problem in undeveloped and developing countries ( 1 ) . the right atrium , right ventricle , and liver have been reported as embolic origins of such cysts ( 4 ) . here , we present a case of embolism of a hydatid cyst inside the left m...
hydatid cyst ( hc ) is a parasitic disease that may involve many organs , especially the lung and the liver . pulmonary artery location of the hydatid cyst is extremely rare , but it may cause life - threatening complications . we report a case of a hydatid cyst that completely filled the left main pulmonary artery...
they are usually originates from the frontal and ethmoid sinus and much less frequently seen in the maxillary and sphenoid sinuses . although the lamina papyracea is a part of ethmoid bone , a giant osteoma originated from the lamina papyracea is very uncommon . headache , proptosis , epiphora , diplopia , dizzines...
introduction : osteomas are slow- growing , benign tumors . they are the most common neoplasms of the paranasal sinuses . they are usually originates from the frontal and ethmoid sinus and much less frequently seen in the maxillary and sphenoid sinuses . although the lamina papyracea is a part of ethmoid bone , a...
it is generally believed that nano - grained ceramics have their unique mechanical characteristics that are not commonly found in their coarse - grained counterparts . strength is an important aspect of material for mechanical and particular applications under loading and static pressure . in some case , it is desira...
we report here experimental results of yield strength and stress relaxation measurements of transparent mgal2o4 nano - ceramics at high pressure and temperature . during compression at ambient temperature , the differential strain deduced from peak broadening increased significantly with pressure up to 2 gpa , with n...
abstractthe prevalence of diabetic nephropathy ( dn ) among diabetic patients seems to be overestimated . recent studies with renal biopsies show that the incidence of non - diabetic nephropathy ( ndn ) among diabetic patients is higher than expected . renal impairment of diabetic patients is frequently attributed ...
a 56-year - old korean woman presented with blurred vision in the right eye of two months duration . she received a pdt treatment for cnv with angioid streaks in her right eye at another medical center one month before presentation . she also had a history of two pdt treatments for cnv with angioid streaks in her o...
a 56-year - old korean woman presented with decreased visual acuity of the right eye . she had a history of two photodynamic therapy treatments for choroidal neovascularization ( cnv ) due to angioid streaks in her left eye with central scarring and low visual acuity . she was diagnosed with subfoveal cnv due to an...
to replace a missing tooth with a dental implant , existence of the adequate bone is an essential prerequisite . sometimes , there is a lack of available bone as a consequence of atrophy , trauma , failure to develop or surgical resection . several grafting materials including autografts , allografts , xenografts a...
objective : both anorganic bovine bone ( abb ) and -tricalcium phosphate ( -tcp ) are used in clinical practice as bone substitute materials , but there is limited data comparing these two materials in standardized defects.the aim of this study was to histologically evaluate the effectiveness of abb and -tcp in the hea...
mycetoma pedis , or madura foot , was first described as a clinical entity by gill in 1842 , from a clinic in madurai , india . in 1880 , carter coined the term mycetoma . the disease can be caused by one of two organisms , the eumyces , or true fungi ( eumycetoma ) , or actinomyces , filamentous bacteria of the or...
mycetoma or maduramycosis is a localized chronic suppurative infection characterized by exuberant granulation tissue , discharging sinuses , and bone involvement later in the course of the disease . early clinical diagnosis before the appearance of sinuses and grains ( aggregates of organism surrounded by granulation...
recent guidelines for the management of hypertension have recognized the relevance of albuminuria and an estimated glomerular filtration rate ( egfr ) value < 60 ml min per 1.73 m on cardiovascular ( cv ) prognosis of hypertensive patients . the presence or absence of albumin in urine and the level of egfr allow p...
our study was aimed to assess the clinical correlates of different degrees of renal dysfunction in a wide group of non - diabetic hypertensive patients , free from cardiovascular ( cv ) complications and known renal diseases , participating to the redhy ( renal dysfunction in hypertension ) study . a total of 1856 hy...
an 18-year - old male reported to outpatient department of deepa nursing home on december 13 , 2013 with the complaint of fever , malaise , myalgia , and unilateral tenderness on the right side of the face with overlying facial edema since 2 days . the pain and swelling were associated with earache and difficulty to ...
mumps is a relatively mild short - term viral infection of the salivary glands that usually occurs during childhood . meningitis / encephalitis is a well - known complication of mumps , but involvement and infection of the testis in adolescent boys and adult men are rare . we report a case of an 18-year - old male ...
diabetic neuropathy is the most common neuropathy and is associated with a wide range of clinical manifestations . it tends to occur after 50 years of age , and mostly in patients with long - standing diabetes mellitus . it results from microvascular injury involving small blood vessels that supply nerves , but mac...
objectives : the pathogenesis of neuropathy in type 2 diabetes mellitus is multifactorial.dyslipidemia may contribute to the development of diabetic neuropathy . this study aimed to assess the atherogenic lipid indices in type 2 diabetic patients with neuropathy.material and methods : fifty - one patients with type 2...
the age - old model of observation followed by attempt ( ie , see one , do one , teach one ) still exists and is still considered common in residency and fellowship training.1 other modalities available to today s medical learner include formal didactic lectures and multimedia learning ( eg , mobile devices , textboo...
the emerging subspecialty of regional anesthesiology and acute pain medicine represents an opportunity to evaluate critically the current methods of teaching regional anesthesia techniques and the practice of acute pain medicine . to date , there have been a wide variety of simulation applications in this field , and...
obesity is a well - established risk factor for obesity - related cancers , especially for crc . the prevalence of obesity has doubled world - wide 1980 and at least 500 million people are classified as obese ( body mass index [ bmi ] 30 kg / m ) . lifestyle - based behavioral and pharmacological interventions for ...
backgroundthe aim of this meta - analysis was to investigate possible relationships between bariatric surgery and incidence of obesity - related cancers . obesity is an established risk factor for obesity - related cancers but the effects of bariatric surgery on incidence of obesity - related cancers are uncertain.ma...
acyclovir and its congeners can rarely result in psychosis , mania and neurotoxicity in elderly , immunocompromised individuals.[14 ] however , there are no reports of acyclovir - associated hypomania in psychiatric population . mrs a is a 55-yr - old lady with bipolar affective disorder for the last 33 years with hy...
acyclovir , a commonly used antiviral drug can rarely result in neuropsychiatric complications especially in elderly . we for the first time report acyclovir associated hypomania in an elderly woman . our report suggests that acyclovir is a risk factor for mood episode in vulnerable individual and one need to be ca...
diabetes mellitus is one of the main endocrine diseases , which is more prevalent in the worldwide . cardio - vascular disease , as one of several chronic disorders , is the major complication of type 2 diabetes mellitus ( t2 dm ) . cardio - vascular disease may result from associated abnormalities of plasma lipid an...
background : alteration in plasma lipid and lipoprotein profile has been documented in diabetic patients . the purpose of this study was to compare the effect of probiotic and conventional yogurt on lipid profile in type 2 diabetes mellitus patients.materials and methods : a total of 44 patients with type 2 diabetes ...
iron deficiency anemia was present in 1% to 2% of adults who according to the third national health and nutrition examination survey ( nhanes iii).2 iron deficiency occurs in 11% of women , most often premenopausal , as well occurring in up to 4% of men . iron deficiency anemia is one of the common anemias and is usu...
we report a rare case of anemia and thrombocytopenia as a result of uterine fibroid and adenomyosis , complicated by immune thrombocytopenic purpura ( itp ) . symptoms were presented as menorrhagia and metrorrhagia in a 34-year - old african american woman , who was later treated with blood and platelet transfusion a...
computer - assisted surgery has been popularized in orthopedic surgery in the last 10 years . whilst a number of recent randomized control trials have shown some benefit in terms of implant position over conventional jig - based referencing,1 many navigation systems require the use of reference arrays , which are fix...
the use of computer navigation has the potential to improve implant position in total knee arthroplasty ( tka ) , but pin fixation of reference arrays introduces an additional potential source of complications . we report a case of vascular injury related to the insertion of a femoral pin during navigated tka .
in this issue of critical care , yildiz and colleagues reported the first randomized , controlled trial on the efficacy and safety of physiologic doses of steroids in severe sepsis . during the past 5 years , five phase ii trials and a phase iii placebo - controlled trial on cortisol replacement , i.e. prolonged treatm...
based on several recently completed randomized controlled trials , cortisol replacement is likely to become a standard of care for vasopressor dependent septic shock . further studies are needed in order to accomplish whether this treatment should be limited to patients with a blunted cortisol response to corticotrop...
gemination is an uncommon anomaly caused by the incomplete attempt of a single tooth bud to form two teeth.1 geminated teeth are found more frequently in primary dentition than permanent dentition.24 the prevalence in the latter ranges from 0.07% to 2.1%.57 maxillary central incisors were found to be the most commonly ...
talon cusps and gemination are rare dental anomalies that can cause significant aesthetic and clinical problems . bilateral talon cusps on geminated teeth have not been reported so far . the case of gemination with talon cusps on both maxillary central incisors was presented in this report . the main complaints o...
infection is probably the most dangerous and feared complication after total hip arthroplasty ( tha ) . since timely treatment is mandatory to increase the chance of success , careful patient monitoring and prompt irrigation and debridement of possibly infected wounds are essential . absorbable sutures are widely use...
absorbable sutures are widely used for wound closure after total hip replacement . here we present two cases of suture - related foreign - body reaction that perfectly mimicked a periprosthetic joint infection , with sterile abscess formation and physical and laboratory signs of inflammation acutely presenting 78 we...
this study assesses whether deprived populations living close to industry experience greater mortality from lung cancer than populations with comparable socioeconomic characteristics living farther away . mortality data , census data , a postal survey of living circumstances , historic and contemporary data on air qual...
neurofibromatosis type 1 ( nf1 ) is a common autosomal dominant genetic disorder with an incidence of approximately 1 in 3,000 - 3,500 individuals worldwide ( 1 ) . nf1 is clinically characterized by the presence of well established phenotypic features , including caf - au - lait ( cal ) spots , neurofibromas , freck...
neurofibromatosis type 1 ( nf1 ) is one of the most commonly inherited autosomal dominant disorders . in order to determine whether genomic alterations and/or chromosomal aberrations involved in the malignant progression of nf1 were present in a korean patient with nf1 , molecular and cytogenetic analyses were perfor...
a 32-year - old male came to us with complaints of cystic lesions in both lids [ figs . 1 , 2a and b ] . he was diagnosed to have lipoid proteinosis elsewhere and was completely screened for systemic involvement . a buccal mucosal biopsy taken elsewhere showed deposition of pas - positive hyaline material [ fig . 3...
urbach wiethe syndrome or lipoid proteinosis is a rare autosomal recessive disorder characterized histologically by infiltration of periodic acid schiff - positive hyaline material in the skin , upper aerodigestive tract , eyelids , and internal organs . classical clinical features include scarring of the skin , bea...
mayaro fever is a dengue - like acute viral disease that is usually self - limiting . its agent is an alphavirus that belongs to the togaviridae family within the semliki forest virus antigenic complex . the first isolation of mayaro virus was made in august and september of 1954 in five febrile patients from mayaro ...
objectives : the objectives of this report were to document the potential presence of mayaro virus infection in ecuador and to examine potential risk factors for mayaro virus infection among the personnel of a military garrison in the amazonian rainforest.materials and methods : the study population consisted of the pe...
the capacity of drugs to inhibit the bile salt export pump ( bsep ) has been correlated with clinical drug induced liver injury ( dili ) . furthermore , known inhibitors of bsep and other bile acid ( ba ) transporters have been implicated in the case studies of dili . glibenclamide has been associated with lobular...
bile salt export pump ( bsep ) inhibition has been proposed to be an important mechanism for drug - induced liver injury ( dili ) . modeling can prioritize knowledge gaps concerning bile acid ( ba ) homeostasis and thus help guide experimentation . a submodel of ba homeostasis in rats and humans was constructed wit...
straight back syndrome has been reported to be a pseudo - heart disease that can mimic congenital abnormalities , especially atrial septal defect ( asd ) ( 1 ) . however , three - dimensional anatomical recognition of this rare disease entity appears to be insufficient . in this case report , we demonstrate the d...
a 23-year - old asymptomatic woman was referred to our hospital for further examination of a systolic ejection murmur with fixed splitting of the second heart sound auscultated at the third left sternal border . initial echocardiography could not detect the cause . subsequently performed low - dose computed tomogra...
primary duodenal tumors are rare , accounting for less than 1% among all gastrointestinal tumors [ 1 , 2 ] . brunner 's gland adenoma , also known as brunner 's hamartoma is a rare benign small bowel neoplasm with an estimated incidence of less than 0.01% . generally , it is an incidental finding discovered in an u...
brunner 's gland adenoma is an extremely rare benign small bowel neoplasm , often discovered incidentally during upper gastrointestinal endoscopy or radiological diagnostics . in few cases , it tends to cause gastrointestinal hemorrhage or intestinal obstruction . we report here our experience with a 47-year - old ...
total knee arthroplasty ( tka ) malalignment is related to an unsatisfactory outcome , including patella maltracking , anterior knee pain , flexion instability and early loosening . furthermore , inadequate positioning particularly of the femoral component is a common indication for revision [ 2 , 8 ] . using the c...
rotation of the femoral component in total knee arthroplasty ( tka ) is of high importance in respect of the balancing of the knee and the patellofemoral joint . though it is shown that computer assisted surgery ( caos ) improves the anteroposterior ( ap ) alignment in tka , it is still unknown whether navigation helps...
the hypoxic pulmonary vasoconstriction ( hpv ) is physiologically and clinically important phenomenon to prevent systemic hypoxemia by diverting pulmonary blood flow from unventilated area to normoxic regions of lung . the oxygen ( o2 ) sensing mechanisms of pulmonary arteries have been long dispute . although the o2...
hypoxic pulmonary vasoconstriction ( hpv ) , a unique response of pulmonary circulation , is critical to prevent hypoxemia under local hypoventilation . hypoxic inhibition of k+ channel is known as an important o2-sensing mechanism in hpv . carbon monoxide ( co ) is suggested as a positive regulator of ca2 + -activ...
traumatic brain injury ( tbi ) caused by a direct mechanical insult to the brain induces cerebral contusion and motor and cognitive dysfunction [ 14 ] . recent studies have indicated that populations of damaged or destroyed neurons can be replenished by proliferation of neural stem cells ( nscs ) [ 5 , 6 ] or newly f...
it remains unclear whether etanercept penetrates directly into the contused brain and improves the outcomes of tbi by attenuating brain contents of tnf- and/or stimulating newly formed neurogenesis . rats that sustained tbi are immediately treated with etanercept . acute neurological and motor injury is assessed in...
there are few evidences about type 2 diabetes mellitus ( t2 dm ) in frail elderly subjects and , specifically , in older patients living in long - term care residences [ 13 ] . these patients have usually reduced life expectancy , poor general health , and at least some degree of functional dependence and/or cognitiv...
prevalence , clinical correlates , and use of glucose - lowering drugs were comprehensively evaluated among 863 nursing home older patients with diabetes ( mean age 82.9 2.1 years ) : functional dependence and cognitive impairment were present in 84.1% and 68% of patients , respectively , and 66.3% of patients had 24 ...
a stroke is a disorder that results from a dysfunction in the brain anatomically due to problems in the cerebrovascular blood supply and vessel hemorrhage . depending on the location and seriousness of the damaged in the brain , stroke patients can have sensory - motor dysfunction , proprioception deficits and ...
[ purpose ] the purpose of this study was to investigate the relationship of knee proprioception with muscle strength and spasticity in stroke patients . [ subjects and methods ] the subjects were 31 stroke patients . the subjects received an explanation of the procedures and methods and provided informed con...
bacterial meningitis is frequently accompanied by intracranial and systemic complications , such as septic shock , adult respiratory distress syndrome , or disseminated intravascular coagulation in children . however , spinal cord involvement is an extremely rare complication of bacterial meningitis in adults5 ) . ...
bacterial meningitis is rarely complicated by an intradural spinal abscess , and recurrent meningitis is an uncommon presentation of a spinal intramedullary abscess . here , we report a 63-year - old patient with recurrent meningitis as the first manifestation of an underlying spinal intramedullary abscess . to the bes...
99% of the 1,000 different mitochondrial proteins are produced on cytosolic ribosomes and are imported into the organelle ( sickmann et al . dolezal et al . , 2006 ; van der laan et al . , 2006a ) . the classic pathway of protein import into mitochondria involves n - terminal presequences on the precursor proteins ...
most mitochondrial proteins are synthesized in the cytosol and imported into one of the four mitochondrial compartments : outer membrane , intermembrane space , inner membrane , and matrix . each compartment contains protein complexes that interact with precursor proteins and promote their transport . these translo...
the simultaneous or sequential development of autoimmune hemolytic anemia ( aiha ) and immune thrombocytopenia ( itp ) and/or immune neutropenia in the absence of any underlying cause was described as the evans syndrome ( es ) by evans et al . , in 1951 . since its first description , es was considered as an idiopath...
evans syndrome is a rare combination of autoimmune hemolytic anemia and immune thrombocytopenia . their association with autoimmune thyroid diseases has been reported by few authors ; however , a sequential development of the evans syndrome in cases of hashimoto 's thyroiditis is extremely rare . the clustering of ...
biomarkers are tools that should aid the physician in diagnosis , in risk stratification with prediction of outcome , and , at best , in clinical decision - making . because the usual renal biomarkers ( for example , serum creatinine and/or urine output ) may fail to detect acute kidney injury ( aki ) at early onset , ...
neutrophil gelatinase - associated lipocalin ( ngal ) is one of the most promising candidate biomarkers of renal injury , with expression in renal tissue increasing dramatically after ischemia - reperfusion injury but not in the case of pure pre - renal failure . in a recent issue of critical care , di somma and collea...
cylindroma is a benign skin adnexal neoplasm that presents in the head and neck region . the tumor may be single or multiple , and is commonly located on the scalp . histopathology is diagnostic with characteristic ' jigsaw puzzle ' architecture and features of ductular differentiation . a 58-year - old man prese...
cylindroma is a benign skin adnexal tumor of eccrine differentiation . clinically , they are disfiguring lesions that can mimic a malignancy . cylindromas can be single or multiple and commonly involve the scalp ( turban tumor ) and face . multiple cylindromas can have a syndromic association as seen in brooke ...
embryonic stem cells have the ability to ultimately differentiate into all types of cells in our bodies , whereas tissue stem cells ( also known as adult stem cells ) serve as immediate sources of cell supply to their resident tissues . stem cell research has offered the promise of effective cell - based therapies in...
stem cells present a vast , new terrain of cell biology . a central question in stem cell research is how stem cells achieve asymmetric divisions to replicate themselves while producing differentiated daughter cells . this hallmark of stem cells is manifested either strictly during each mitosis or loosely among sev...
cardiovascular disease ( cvd ) is the main cause of death and it imposes a burden across the world.1 ) developed countries have already reduced the cvd mortality rate considerably through the identification and selection of high - risk groups , and the application of direct interventions , such as education and the pre...
background and objectivesthe objective of this study was to analyze cardiovascular risk factors in adults with congenital heart disease ( achd).subjects and methodsthe subjects for this study comprised 135 patients , aged 18 years and above , who visited the achd clinic at the samsung medical center and 135 adults with...