[
  {
    "dataset": "vesuvius",
    "organism": "HeLa (human cervical carcinoma)",
    "perturbation_type": "CRISPRko",
    "perturbation_scale": "5,072 genes (20,537 sgRNAs)",
    "sgrnas_per_gene_median": 4,
    "hierarchy": "cell \u2192 sgRNA \u2192 gene",
    "image_format": "PNG montages (2700\u00d72000)",
    "channels": "4 (DNA, Tubulin, \u03b3H2AX, Actin)",
    "public_access": true,
    "archive": "Vesuvius portal (Whitehead Institute)",
    "license": "Research use",
    "benchmark_ready": true,
    "benchmark_ready_reason": "Montage images + 98 phenotype features + cluster labels"
  },
  {
    "dataset": "idr0071",
    "organism": "A549 (human lung carcinoma)",
    "perturbation_type": "CRISPRko",
    "perturbation_scale": "949 genes (experiment C)",
    "sgrnas_per_gene_median": 6,
    "hierarchy": "cell \u2192 sgRNA \u2192 gene",
    "image_format": "TIFF (16-bit)",
    "channels": "SBS + phenotype (DAPI, p65 antibody)",
    "public_access": true,
    "archive": "Cell-IDR (idr0071)",
    "license": "CC BY 4.0",
    "benchmark_ready": false,
    "benchmark_ready_reason": "No pre-processed montages or phenotype features",
    "sample_tiff": {
      "path": "data/raw/idr0071/experimentC/input/10X_c1-SBS-1/10X_c1-SBS-1_A1_Tile-10.sbs.tif",
      "width": 1024,
      "height": 1024,
      "bits_per_sample": 16
    }
  },
  {
    "dataset": "carlson_irf3",
    "organism": "A549 (human lung carcinoma)",
    "perturbation_type": "CRISPRko",
    "perturbation_scale": "~20,000 genes (80,408 sgRNAs)",
    "sgrnas_per_gene_median": 4,
    "hierarchy": "cell \u2192 sgRNA \u2192 gene",
    "image_format": "TIFF (16-bit, big-endian)",
    "channels": 7,
    "public_access": true,
    "archive": "Google Cloud Storage (requester-pays)",
    "license": "Research use",
    "benchmark_ready": false,
    "benchmark_ready_reason": "No pre-processed montages or phenotype features",
    "sample_tiff": {
      "path": "data/raw/carlson_irf3/sample/Figure1_Larger_FOV_WellA1_site1014_DAPI_MDA5_pIRF3_RIG-I_SeV_Mito_Pex.tif",
      "width": 1140,
      "height": 1140,
      "bits_per_sample": 32
    }
  },
  {
    "dataset": "crisprmap",
    "organism": "Various (multimodal CRISPR phenotyping)",
    "perturbation_type": "CRISPRko/CRISPRi",
    "perturbation_scale": "~500 genes",
    "sgrnas_per_gene_median": "unknown",
    "hierarchy": "cell \u2192 sgRNA \u2192 gene",
    "image_format": "Imaris .ims (proprietary)",
    "channels": "Multiple fluorescence",
    "public_access": true,
    "archive": "BioImage Archive (S-BIAD985)",
    "license": "CC BY 4.0",
    "benchmark_ready": false,
    "benchmark_ready_reason": "Proprietary image format, no processed features",
    "sample_file_count": 10
  },
  {
    "dataset": "perturbmap",
    "organism": "Mouse (in vivo lymphoid)",
    "perturbation_type": "CRISPRko (in vivo spatial)",
    "perturbation_scale": "~30 genes",
    "sgrnas_per_gene_median": "unknown",
    "hierarchy": "cell \u2192 sgRNA \u2192 gene (spatial context)",
    "image_format": "Derived annotations only (JSON)",
    "channels": "N/A (segmentation + annotations)",
    "public_access": "Partial (annotations public, raw on request)",
    "archive": "BioImage Archive (S-BIAD267)",
    "license": "Research use",
    "benchmark_ready": false,
    "benchmark_ready_reason": "Derived data only, raw imaging on request"
  }
]