--- id: "56eo2D2O" recording_id: "56eo2D2O" audio_file: "audio/56eo2D2O.mp3" parent_id: null title: "Considering montelukast after barbecue smoke asthma trigger in Israel" recorded_at: "2026-04-26T10:47:36.000000Z" created_at: "2026-04-26T10:47:41.000000Z" updated_at: "2026-04-26T10:48:03.000000Z" duration: 225883 public_slug: null is_published: 0 recording_type: 1 user_id: 131594 user_name: "Daniel Rosehill" tags: - "Testing" - "Idea" - "Medication" - "Work" - "My Weird Prompts - Generate" --- # Considering montelukast after barbecue smoke asthma trigger in Israel Hi there, Herman and Corn. So I was enjoying Independence Day in Israel a few days ago when suddenly, to make myself sound very pathetic, my lungs began constraining due to the, um, a huge amount of barbecue smoke. On Independence Day in Israel, everybody marks it with barbecues. And I was thinking that, um, I need to get on Montelukast or Singular, and I, uh, have to be honest, my main hesitation has been not wanting to be on so many different medications, and I felt like it's one I could avoid. Um, but it's for these reasons. When I find my lungs are, like, reacting to a certain trigger, that I think to myself, how nice would it be to not have this happen? Because it's not just about these occasional smoke triggers. It's like, you know, you could be in someone's house and they have, I don't know, a bit of second-hand smoke in the background or a dog, something that triggers your asthma. And I think it creates this fear that actually probably makes your asthma control worse because you're always worried about the environment not triggering your breathing, and I think that's really limiting.

What I'd love to understand a bit about Herman and Corn—we did we have kind of talked about this in some previous episodes, um—but we talk about airway sensitivity, that when this happens, it's not that smoke is good. Um, it's, you know, we can it's it's b smoke is ba is harmful for breathing, right? So but if we were to look at the inside the lungs of someone without asthma and someone with asthma, we'd see that the response in the asthmatic is just exaggerated. Um, it's the same stimulus, but the asthmatic is reacting not, you know, in an unhelpful way. It's disproportionate.

Um, and my question is, if we'd when we talk about asthma control and this multi-medication reality that I kind of hate, we might need an inhaler plus Singular. Maybe some people also need an antihistamine. But we're adding these layers together, and how do they achieve this reduction in sensitivity? Um, one thing that I've always been an idea that I found attractive but never actually, uh, did it is these allergy shots where I think they try to make this long-lasting. But I think if I did the testing, it found I was allergic to trees, and then you have to commit to or it wasn't very conclusive, and you have to commit to this, like, very, very long and regimented process of getting these allergy shots, which is itself very inconvenient.

Um, I guess I would kind of love to see the day where you just get one, you know, intervention that remodels your response. But until we get to that day, I'm curious to know how this allergy reduction occurs and to what extent it is synergistic. Because I think that's the biggest argument in favor of multi-medication regimes, is the idea that, um, if, you know, for people like me who are hesitant about it, I think if we understood that there are additive or synergistic effects, um, it would be useful to know. So how how does how does that work when you have your baseline inhaler doing some delivering a, uh, corticosteroid and then you add in Singular? How does that collectively reduce those, um, those trigger events?