Datasets:
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Browse files- README +4 -0
- dataset_description.json +23 -0
- derivatives/.DS_Store +0 -0
- derivatives/fmriprep/dataset_description.json +11 -0
- derivatives/fmriprep/logs/CITATION.bib +340 -0
- derivatives/fmriprep/logs/CITATION.html +83 -0
- derivatives/fmriprep/logs/CITATION.md +110 -0
- derivatives/fmriprep/logs/CITATION.tex +166 -0
- derivatives/fmriprep/sub-S01.html +867 -0
- derivatives/fmriprep/sub-S02.html +867 -0
- derivatives/fmriprep/sub-S03.html +867 -0
- derivatives/fmriprep/sub-S04.html +859 -0
- derivatives/fmriprep/sub-S05.html +859 -0
- derivatives/fmriprep/sub-S06.html +859 -0
- derivatives/fmriprep/sub-S07.html +859 -0
- derivatives/fmriprep/sub-S08.html +859 -0
- derivatives/fmriprep/sub-S09.html +859 -0
- derivatives/fmriprep/sub-S10.html +867 -0
- derivatives/fmriprep/sub-S11.html +867 -0
- derivatives/fmriprep/sub-S12.html +867 -0
- derivatives/fmriprep/sub-S13.html +859 -0
- derivatives/fmriprep/sub-S14.html +867 -0
- derivatives/fmriprep/sub-S15.html +867 -0
- derivatives/fmriprep/sub-S16.html +867 -0
- derivatives/fmriprep/sub-S17.html +867 -0
- derivatives/fmriprep/sub-S18.html +859 -0
- derivatives/fmriprep/sub-S19.html +867 -0
- derivatives/fmriprep/sub-S19/anat/sub-S19_desc-preproc_T1w.json +3 -0
- derivatives/fmriprep/sub-S20.html +867 -0
- participants.json +22 -0
- participants.tsv +21 -0
- phenotype/behavioural.tsv +95 -0
- phenotype/subject.tsv +95 -0
- sub-S01/.DS_Store +0 -0
- sub-S02/func/sub-S02_task-localizer_events.tsv +81 -0
- sub-S03/func/sub-S03_task-localizer_events.tsv +81 -0
- sub-S04/func/sub-S04_task-localizer_events.tsv +81 -0
- sub-S05/func/sub-S05_task-localizer_events.tsv +81 -0
- sub-S10/func/sub-S10_task-localizer_events.tsv +81 -0
- sub-S11/func/sub-S11_task-localizer_events.tsv +81 -0
- sub-S12/func/sub-S12_task-localizer_events.tsv +81 -0
- sub-S13/func/sub-S13_task-localizer_events.tsv +81 -0
- sub-S14/func/sub-S14_task-localizer_events.tsv +81 -0
- sub-S15/func/sub-S15_task-localizer_events.tsv +81 -0
- sub-S16/func/sub-S16_task-localizer_events.tsv +81 -0
- sub-S17/func/sub-S17_task-localizer_events.tsv +81 -0
- sub-S18/func/sub-S18_task-localizer_events.tsv +81 -0
- sub-S19/func/sub-S19_task-localizer_events.tsv +81 -0
- sub-S20/func/sub-S20_task-localizer_events.tsv +81 -0
- task-localizer_bold.json +9 -0
README
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The Brainomics/Localizer dataset is a subset of the Functional Localizer dataset.
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For more details have a look at the dataset DOI landing page:
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https://doi.org/10.25720/1ca1-0sfd
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dataset_description.json
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{
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"BIDSVersion": "1.0.2",
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"Name": "Brainomics/Localizer",
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"License": "Creative Commons Attribution-NonCommercial 4.0 International",
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"Authors": [
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"Dimitri Papadopoulos Orfanos",
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"Vincent Michel",
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"Yannick Schwartza",
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"Philippe Pinel",
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"Antonio Moreno",
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"Denis Le Bihan",
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"Vincent Frouin"
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],
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"Acknowledgements": "We thank Stanislas Dehaene for his participation to the creation of the Localizer database and Bernadette Martins for helping us navigate through regulatory rules. We thank the Inria-CEA Parietal team and in particular Virgile Fritsch for the Localizer data fetcher in NiLearn.",
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"HowToAcknowledge": "Papadopoulos Orfanos, D., Michel, V., Schwartz, Y., Pinel, P., Moreno, A., Le Bihan, D., & Frouin, V. (2017). The Brainomics/Localizer database. NeuroImage, 144, 309\u2013314. doi:10.1016/j.neuroimage.2015.09.052",
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"Funding": [
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"ANR-10-BINF-04"
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],
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"ReferencesAndLinks": [
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"Papadopoulos Orfanos, D., Michel, V., Schwartz, Y., Pinel, P., Moreno, A., Le Bihan, D., & Frouin, V. (2017). The Brainomics/Localizer database. NeuroImage, 144, 309\u2013314. doi:10.1016/j.neuroimage.2015.09.052",
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"Pinel, P., Thirion, B., Meriaux, S., Jobert, A., Serres, J., Le Bihan, D., Poline, J.-B., & Dehaene, S. (2007). Fast reproducible identification and large-scale databasing of individual functional cognitive networks BMC Neurosci., 8 (1) (2007), p. 91, 10.1186/1471-2202-8-91"
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]
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}
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derivatives/.DS_Store
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Binary file (6.15 kB). View file
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derivatives/fmriprep/dataset_description.json
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{
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"Name": "fMRIPrep - fMRI PREProcessing workflow",
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"BIDSVersion": "1.1.1",
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"PipelineDescription": {
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"Name": "fMRIPrep",
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"Version": "20.0.6",
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"CodeURL": "https://github.com/poldracklab/fmriprep/archive/20.0.6.tar.gz"
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},
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"CodeURL": "https://github.com/poldracklab/fmriprep",
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"HowToAcknowledge": "Please cite our paper (https://doi.org/10.1038/s41592-018-0235-4), and include the generated citation boilerplate within the Methods section of the text."
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}
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derivatives/fmriprep/logs/CITATION.bib
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| 1 |
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@article{fmriprep1,
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| 2 |
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author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
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| 3 |
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title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
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| 4 |
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year = {2018},
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| 5 |
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doi = {10.1038/s41592-018-0235-4},
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| 6 |
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journal = {Nature Methods}
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| 7 |
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}
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| 8 |
+
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| 9 |
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@article{fmriprep2,
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| 10 |
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author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
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| 11 |
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title = {fMRIPrep},
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| 12 |
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year = 2018,
|
| 13 |
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doi = {10.5281/zenodo.852659},
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| 14 |
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publisher = {Zenodo},
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| 15 |
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journal = {Software}
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| 16 |
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}
|
| 17 |
+
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| 18 |
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@article{nipype1,
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| 19 |
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author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
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| 20 |
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doi = {10.3389/fninf.2011.00013},
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| 21 |
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journal = {Frontiers in Neuroinformatics},
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| 22 |
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pages = 13,
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| 23 |
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shorttitle = {Nipype},
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| 24 |
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title = {Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in Python},
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| 25 |
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volume = 5,
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| 26 |
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year = 2011
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| 27 |
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}
|
| 28 |
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| 29 |
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@article{nipype2,
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| 30 |
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author = {Gorgolewski, Krzysztof J. and Esteban, Oscar and Markiewicz, Christopher J. and Ziegler, Erik and Ellis, David Gage and Notter, Michael Philipp and Jarecka, Dorota and Johnson, Hans and Burns, Christopher and Manhães-Savio, Alexandre and Hamalainen, Carlo and Yvernault, Benjamin and Salo, Taylor and Jordan, Kesshi and Goncalves, Mathias and Waskom, Michael and Clark, Daniel and Wong, Jason and Loney, Fred and Modat, Marc and Dewey, Blake E and Madison, Cindee and Visconti di Oleggio Castello, Matteo and Clark, Michael G. and Dayan, Michael and Clark, Dav and Keshavan, Anisha and Pinsard, Basile and Gramfort, Alexandre and Berleant, Shoshana and Nielson, Dylan M. and Bougacha, Salma and Varoquaux, Gael and Cipollini, Ben and Markello, Ross and Rokem, Ariel and Moloney, Brendan and Halchenko, Yaroslav O. and Wassermann , Demian and Hanke, Michael and Horea, Christian and Kaczmarzyk, Jakub and Gilles de Hollander and DuPre, Elizabeth and Gillman, Ashley and Mordom, David and Buchanan, Colin and Tungaraza, Rosalia and Pauli, Wolfgang M. and Iqbal, Shariq and Sikka, Sharad and Mancini, Matteo and Schwartz, Yannick and Malone, Ian B. and Dubois, Mathieu and Frohlich, Caroline and Welch, David and Forbes, Jessica and Kent, James and Watanabe, Aimi and Cumba, Chad and Huntenburg, Julia M. and Kastman, Erik and Nichols, B. Nolan and Eshaghi, Arman and Ginsburg, Daniel and Schaefer, Alexander and Acland, Benjamin and Giavasis, Steven and Kleesiek, Jens and Erickson, Drew and Küttner, René and Haselgrove, Christian and Correa, Carlos and Ghayoor, Ali and Liem, Franz and Millman, Jarrod and Haehn, Daniel and Lai, Jeff and Zhou, Dale and Blair, Ross and Glatard, Tristan and Renfro, Mandy and Liu, Siqi and Kahn, Ari E. and Pérez-García, Fernando and Triplett, William and Lampe, Leonie and Stadler, Jörg and Kong, Xiang-Zhen and Hallquist, Michael and Chetverikov, Andrey and Salvatore, John and Park, Anne and Poldrack, Russell and Craddock, R. Cameron and Inati, Souheil and Hinds, Oliver and Cooper, Gavin and Perkins, L. Nathan and Marina, Ana and Mattfeld, Aaron and Noel, Maxime and Lukas Snoek and Matsubara, K and Cheung, Brian and Rothmei, Simon and Urchs, Sebastian and Durnez, Joke and Mertz, Fred and Geisler, Daniel and Floren, Andrew and Gerhard, Stephan and Sharp, Paul and Molina-Romero, Miguel and Weinstein, Alejandro and Broderick, William and Saase, Victor and Andberg, Sami Kristian and Harms, Robbert and Schlamp, Kai and Arias, Jaime and Papadopoulos Orfanos, Dimitri and Tarbert, Claire and Tambini, Arielle and De La Vega, Alejandro and Nickson, Thomas and Brett, Matthew and Falkiewicz, Marcel and Podranski, Kornelius and Linkersdörfer, Janosch and Flandin, Guillaume and Ort, Eduard and Shachnev, Dmitry and McNamee, Daniel and Davison, Andrew and Varada, Jan and Schwabacher, Isaac and Pellman, John and Perez-Guevara, Martin and Khanuja, Ranjeet and Pannetier, Nicolas and McDermottroe, Conor and Ghosh, Satrajit},
|
| 31 |
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title = {Nipype},
|
| 32 |
+
year = 2018,
|
| 33 |
+
doi = {10.5281/zenodo.596855},
|
| 34 |
+
publisher = {Zenodo},
|
| 35 |
+
journal = {Software}
|
| 36 |
+
}
|
| 37 |
+
|
| 38 |
+
@article{n4,
|
| 39 |
+
author = {Tustison, N. J. and Avants, B. B. and Cook, P. A. and Zheng, Y. and Egan, A. and Yushkevich, P. A. and Gee, J. C.},
|
| 40 |
+
doi = {10.1109/TMI.2010.2046908},
|
| 41 |
+
issn = {0278-0062},
|
| 42 |
+
journal = {IEEE Transactions on Medical Imaging},
|
| 43 |
+
number = 6,
|
| 44 |
+
pages = {1310-1320},
|
| 45 |
+
shorttitle = {N4ITK},
|
| 46 |
+
title = {N4ITK: Improved N3 Bias Correction},
|
| 47 |
+
volume = 29,
|
| 48 |
+
year = 2010
|
| 49 |
+
}
|
| 50 |
+
|
| 51 |
+
@article{fs_reconall,
|
| 52 |
+
author = {Dale, Anders M. and Fischl, Bruce and Sereno, Martin I.},
|
| 53 |
+
doi = {10.1006/nimg.1998.0395},
|
| 54 |
+
issn = {1053-8119},
|
| 55 |
+
journal = {NeuroImage},
|
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<body>
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| 19 |
+
<p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
|
| 20 |
+
<dl>
|
| 21 |
+
<dt>Anatomical data preprocessing</dt>
|
| 22 |
+
<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
|
| 23 |
+
</dd>
|
| 24 |
+
<dt>Functional data preprocessing</dt>
|
| 25 |
+
<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
|
| 26 |
+
</dd>
|
| 27 |
+
</dl>
|
| 28 |
+
<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
|
| 29 |
+
<h3 id="copyright-waiver">Copyright Waiver</h3>
|
| 30 |
+
<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
|
| 31 |
+
<h3 id="references" class="unnumbered">References</h3>
|
| 32 |
+
<div id="refs" class="references">
|
| 33 |
+
<div id="ref-nilearn">
|
| 34 |
+
<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
|
| 35 |
+
</div>
|
| 36 |
+
<div id="ref-ants">
|
| 37 |
+
<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
|
| 38 |
+
</div>
|
| 39 |
+
<div id="ref-compcor">
|
| 40 |
+
<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
|
| 41 |
+
</div>
|
| 42 |
+
<div id="ref-fmriprep2">
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| 43 |
+
<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
|
| 44 |
+
</div>
|
| 45 |
+
<div id="ref-fmriprep1">
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| 46 |
+
<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
|
| 47 |
+
</div>
|
| 48 |
+
<div id="ref-mni152nlin2009casym">
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| 49 |
+
<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
|
| 50 |
+
</div>
|
| 51 |
+
<div id="ref-nipype1">
|
| 52 |
+
<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
|
| 53 |
+
</div>
|
| 54 |
+
<div id="ref-nipype2">
|
| 55 |
+
<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
|
| 56 |
+
</div>
|
| 57 |
+
<div id="ref-bbr">
|
| 58 |
+
<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
|
| 59 |
+
</div>
|
| 60 |
+
<div id="ref-mcflirt">
|
| 61 |
+
<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
|
| 62 |
+
</div>
|
| 63 |
+
<div id="ref-flirt">
|
| 64 |
+
<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
|
| 65 |
+
</div>
|
| 66 |
+
<div id="ref-lanczos">
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| 67 |
+
<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
|
| 68 |
+
</div>
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| 69 |
+
<div id="ref-power_fd_dvars">
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| 70 |
+
<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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| 71 |
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</div>
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| 72 |
+
<div id="ref-confounds_satterthwaite_2013">
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| 73 |
+
<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
|
| 74 |
+
</div>
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| 75 |
+
<div id="ref-n4">
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| 76 |
+
<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
|
| 77 |
+
</div>
|
| 78 |
+
<div id="ref-fsl_fast">
|
| 79 |
+
<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
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</div>
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</div>
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</body>
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</html>
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derivatives/fmriprep/logs/CITATION.md
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|
| 1 |
+
|
| 2 |
+
Results included in this manuscript come from preprocessing
|
| 3 |
+
performed using *fMRIPrep* 20.0.6
|
| 4 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 5 |
+
which is based on *Nipype* 1.4.2
|
| 6 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 7 |
+
|
| 8 |
+
Anatomical data preprocessing
|
| 9 |
+
|
| 10 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 11 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 12 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 13 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 14 |
+
as target template.
|
| 15 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 16 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 17 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 18 |
+
@fsl_fast].
|
| 19 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 20 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 21 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 22 |
+
The following template was selected for spatial normalization:
|
| 23 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 24 |
+
|
| 25 |
+
Functional data preprocessing
|
| 26 |
+
|
| 27 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 28 |
+
tasks and sessions), the following preprocessing was performed.
|
| 29 |
+
First, a reference volume and its skull-stripped version were generated
|
| 30 |
+
using a custom methodology of *fMRIPrep*.
|
| 31 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 32 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 33 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 34 |
+
cost-function.
|
| 35 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 36 |
+
for distortions remaining in the BOLD reference.
|
| 37 |
+
Head-motion parameters with respect to the BOLD reference
|
| 38 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 39 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 40 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 41 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 42 |
+
were resampled onto their original, native space by applying
|
| 43 |
+
the transforms to correct for head-motion.
|
| 44 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 45 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 46 |
+
The BOLD time-series were resampled into standard space,
|
| 47 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 48 |
+
First, a reference volume and its skull-stripped version were generated
|
| 49 |
+
using a custom methodology of *fMRIPrep*.
|
| 50 |
+
Several confounding time-series were calculated based on the
|
| 51 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 52 |
+
three region-wise global signals.
|
| 53 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 54 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 55 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 56 |
+
the whole-brain masks.
|
| 57 |
+
Additionally, a set of physiological regressors were extracted to
|
| 58 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 59 |
+
Principal components are estimated after high-pass filtering the
|
| 60 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 61 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 62 |
+
and anatomical (aCompCor).
|
| 63 |
+
tCompCor components are then calculated from the top 5% variable
|
| 64 |
+
voxels within a mask covering the subcortical regions.
|
| 65 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 66 |
+
which ensures it does not include cortical GM regions.
|
| 67 |
+
For aCompCor, components are calculated within the intersection of
|
| 68 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 69 |
+
in T1w space, after their projection to the native space of each
|
| 70 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 71 |
+
are also calculated separately within the WM and CSF masks.
|
| 72 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 73 |
+
values are retained, such that the retained components' time series are
|
| 74 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 75 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 76 |
+
consideration.
|
| 77 |
+
The head-motion estimates calculated in the correction step were also
|
| 78 |
+
placed within the corresponding confounds file.
|
| 79 |
+
The confound time series derived from head motion estimates and global
|
| 80 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 81 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 82 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 83 |
+
were annotated as motion outliers.
|
| 84 |
+
All resamplings can be performed with *a single interpolation
|
| 85 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 86 |
+
transform matrices, susceptibility distortion correction when available,
|
| 87 |
+
and co-registrations to anatomical and output spaces).
|
| 88 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 89 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 90 |
+
effects of other kernels [@lanczos].
|
| 91 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 92 |
+
(FreeSurfer).
|
| 93 |
+
|
| 94 |
+
|
| 95 |
+
Many internal operations of *fMRIPrep* use
|
| 96 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 97 |
+
mostly within the functional processing workflow.
|
| 98 |
+
For more details of the pipeline, see [the section corresponding
|
| 99 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 100 |
+
|
| 101 |
+
|
| 102 |
+
### Copyright Waiver
|
| 103 |
+
|
| 104 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 105 |
+
with the express intention that users should copy and paste this
|
| 106 |
+
text into their manuscripts *unchanged*.
|
| 107 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 108 |
+
|
| 109 |
+
### References
|
| 110 |
+
|
derivatives/fmriprep/logs/CITATION.tex
ADDED
|
@@ -0,0 +1,166 @@
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|
|
|
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|
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|
| 1 |
+
\PassOptionsToPackage{unicode=true}{hyperref} % options for packages loaded elsewhere
|
| 2 |
+
\PassOptionsToPackage{hyphens}{url}
|
| 3 |
+
%
|
| 4 |
+
\documentclass[]{article}
|
| 5 |
+
\usepackage{lmodern}
|
| 6 |
+
\usepackage{amssymb,amsmath}
|
| 7 |
+
\usepackage{ifxetex,ifluatex}
|
| 8 |
+
\usepackage{fixltx2e} % provides \textsubscript
|
| 9 |
+
\ifnum 0\ifxetex 1\fi\ifluatex 1\fi=0 % if pdftex
|
| 10 |
+
\usepackage[T1]{fontenc}
|
| 11 |
+
\usepackage[utf8]{inputenc}
|
| 12 |
+
\usepackage{textcomp} % provides euro and other symbols
|
| 13 |
+
\else % if luatex or xelatex
|
| 14 |
+
\usepackage{unicode-math}
|
| 15 |
+
\defaultfontfeatures{Ligatures=TeX,Scale=MatchLowercase}
|
| 16 |
+
\fi
|
| 17 |
+
% use upquote if available, for straight quotes in verbatim environments
|
| 18 |
+
\IfFileExists{upquote.sty}{\usepackage{upquote}}{}
|
| 19 |
+
% use microtype if available
|
| 20 |
+
\IfFileExists{microtype.sty}{%
|
| 21 |
+
\usepackage[]{microtype}
|
| 22 |
+
\UseMicrotypeSet[protrusion]{basicmath} % disable protrusion for tt fonts
|
| 23 |
+
}{}
|
| 24 |
+
\IfFileExists{parskip.sty}{%
|
| 25 |
+
\usepackage{parskip}
|
| 26 |
+
}{% else
|
| 27 |
+
\setlength{\parindent}{0pt}
|
| 28 |
+
\setlength{\parskip}{6pt plus 2pt minus 1pt}
|
| 29 |
+
}
|
| 30 |
+
\usepackage{hyperref}
|
| 31 |
+
\hypersetup{
|
| 32 |
+
pdfborder={0 0 0},
|
| 33 |
+
breaklinks=true}
|
| 34 |
+
\urlstyle{same} % don't use monospace font for urls
|
| 35 |
+
\setlength{\emergencystretch}{3em} % prevent overfull lines
|
| 36 |
+
\providecommand{\tightlist}{%
|
| 37 |
+
\setlength{\itemsep}{0pt}\setlength{\parskip}{0pt}}
|
| 38 |
+
\setcounter{secnumdepth}{0}
|
| 39 |
+
% Redefines (sub)paragraphs to behave more like sections
|
| 40 |
+
\ifx\paragraph\undefined\else
|
| 41 |
+
\let\oldparagraph\paragraph
|
| 42 |
+
\renewcommand{\paragraph}[1]{\oldparagraph{#1}\mbox{}}
|
| 43 |
+
\fi
|
| 44 |
+
\ifx\subparagraph\undefined\else
|
| 45 |
+
\let\oldsubparagraph\subparagraph
|
| 46 |
+
\renewcommand{\subparagraph}[1]{\oldsubparagraph{#1}\mbox{}}
|
| 47 |
+
\fi
|
| 48 |
+
|
| 49 |
+
% set default figure placement to htbp
|
| 50 |
+
\makeatletter
|
| 51 |
+
\def\fps@figure{htbp}
|
| 52 |
+
\makeatother
|
| 53 |
+
|
| 54 |
+
\usepackage[]{natbib}
|
| 55 |
+
\bibliographystyle{plainnat}
|
| 56 |
+
|
| 57 |
+
\date{}
|
| 58 |
+
|
| 59 |
+
\begin{document}
|
| 60 |
+
|
| 61 |
+
Results included in this manuscript come from preprocessing performed
|
| 62 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 63 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 64 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 65 |
+
|
| 66 |
+
\begin{description}
|
| 67 |
+
\item[Anatomical data preprocessing]
|
| 68 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 69 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 70 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 71 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 72 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 73 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 74 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 75 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 76 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 77 |
+
Volume-based spatial normalization to one standard space
|
| 78 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 79 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 80 |
+
of both T1w reference and the T1w template. The following template was
|
| 81 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 82 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 83 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 84 |
+
\item[Functional data preprocessing]
|
| 85 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 86 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 87 |
+
volume and its skull-stripped version were generated using a custom
|
| 88 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 89 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 90 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 91 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 92 |
+
was configured with nine degrees of freedom to account for distortions
|
| 93 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 94 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 95 |
+
rotation and translation parameters) are estimated before any
|
| 96 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 97 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 98 |
+
correction when applied) were resampled onto their original, native
|
| 99 |
+
space by applying the transforms to correct for head-motion. These
|
| 100 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 101 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 102 |
+
time-series were resampled into standard space, generating a
|
| 103 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 104 |
+
reference volume and its skull-stripped version were generated using a
|
| 105 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 106 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 107 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 108 |
+
DVARS are calculated for each functional run, both using their
|
| 109 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 110 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 111 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 112 |
+
physiological regressors were extracted to allow for component-based
|
| 113 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 114 |
+
components are estimated after high-pass filtering the
|
| 115 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 116 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 117 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 118 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 119 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 120 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 121 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 122 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 123 |
+
in T1w space, after their projection to the native space of each
|
| 124 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 125 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 126 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 127 |
+
singular values are retained, such that the retained components' time
|
| 128 |
+
series are sufficient to explain 50 percent of variance across the
|
| 129 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 130 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 131 |
+
the correction step were also placed within the corresponding confounds
|
| 132 |
+
file. The confound time series derived from head motion estimates and
|
| 133 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 134 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 135 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 136 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 137 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 138 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 139 |
+
distortion correction when available, and co-registrations to anatomical
|
| 140 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 141 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 142 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 143 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 144 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 145 |
+
\end{description}
|
| 146 |
+
|
| 147 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 148 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 149 |
+
processing workflow. For more details of the pipeline, see
|
| 150 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 151 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 152 |
+
|
| 153 |
+
\hypertarget{copyright-waiver}{%
|
| 154 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 155 |
+
|
| 156 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 157 |
+
the express intention that users should copy and paste this text into
|
| 158 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 159 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 160 |
+
|
| 161 |
+
\hypertarget{references}{%
|
| 162 |
+
\subsubsection{References}\label{references}}
|
| 163 |
+
|
| 164 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}
|
| 165 |
+
|
| 166 |
+
\end{document}
|
derivatives/fmriprep/sub-S01.html
ADDED
|
@@ -0,0 +1,867 @@
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|
| 1 |
+
<?xml version="1.0" encoding="utf-8" ?>
|
| 2 |
+
<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
|
| 3 |
+
<html xmlns="http://www.w3.org/1999/xhtml" xml:lang="en" lang="en">
|
| 4 |
+
<head>
|
| 5 |
+
<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
|
| 6 |
+
<meta name="generator" content="Docutils 0.12: http://docutils.sourceforge.net/" />
|
| 7 |
+
<title></title>
|
| 8 |
+
<script src="https://code.jquery.com/jquery-3.3.1.slim.min.js" integrity="sha384-q8i/X+965DzO0rT7abK41JStQIAqVgRVzpbzo5smXKp4YfRvH+8abtTE1Pi6jizo" crossorigin="anonymous"></script>
|
| 9 |
+
<script src="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/js/bootstrap.min.js" integrity="sha384-ChfqqxuZUCnJSK3+MXmPNIyE6ZbWh2IMqE241rYiqJxyMiZ6OW/JmZQ5stwEULTy" crossorigin="anonymous"></script>
|
| 10 |
+
<link rel="stylesheet" href="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/css/bootstrap.min.css" integrity="sha384-MCw98/SFnGE8fJT3GXwEOngsV7Zt27NXFoaoApmYm81iuXoPkFOJwJ8ERdknLPMO" crossorigin="anonymous">
|
| 11 |
+
<style type="text/css">
|
| 12 |
+
.sub-report-title {}
|
| 13 |
+
.run-title {}
|
| 14 |
+
|
| 15 |
+
h1 { padding-top: 35px; }
|
| 16 |
+
h2 { padding-top: 20px; }
|
| 17 |
+
h3 { padding-top: 15px; }
|
| 18 |
+
|
| 19 |
+
.elem-desc {}
|
| 20 |
+
.elem-caption {
|
| 21 |
+
margin-top: 15px
|
| 22 |
+
margin-bottom: 0;
|
| 23 |
+
}
|
| 24 |
+
.elem-filename {}
|
| 25 |
+
|
| 26 |
+
div.elem-image {
|
| 27 |
+
width: 100%;
|
| 28 |
+
page-break-before:always;
|
| 29 |
+
}
|
| 30 |
+
|
| 31 |
+
.elem-image object.svg-reportlet {
|
| 32 |
+
width: 100%;
|
| 33 |
+
padding-bottom: 5px;
|
| 34 |
+
}
|
| 35 |
+
body {
|
| 36 |
+
padding: 65px 10px 10px;
|
| 37 |
+
}
|
| 38 |
+
|
| 39 |
+
.boiler-html {
|
| 40 |
+
font-family: "Bitstream Charter", "Georgia", Times;
|
| 41 |
+
margin: 20px 25px;
|
| 42 |
+
padding: 10px;
|
| 43 |
+
background-color: #F8F9FA;
|
| 44 |
+
}
|
| 45 |
+
|
| 46 |
+
div#boilerplate pre {
|
| 47 |
+
margin: 20px 25px;
|
| 48 |
+
padding: 10px;
|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
+
|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
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<div id="Summary">
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<h1 class="sub-report-title">Summary</h1>
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<div id="datatype-anat_desc-summary_suffix-T1w">
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<ul class="elem-desc">
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<li>Subject ID: S01</li>
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<li>Structural images: 1 T1-weighted </li>
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<li>Functional series: 1</li>
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<ul class="elem-desc">
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<li>Task: localizer (1 run)</li>
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</ul>
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<li>Standard output spaces: MNI152NLin2009cAsym</li>
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<li>Non-standard output spaces: </li>
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<li>FreeSurfer reconstruction: Not run</li>
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</ul>
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</div>
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</div>
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<div id="Anatomical">
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<h1 class="sub-report-title">Anatomical</h1>
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<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
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<h3 class="elem-title">Anatomical Conformation</h3>
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<ul class="elem-desc">
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<li>Input T1w images: 1</li>
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<li>Output orientation: RAS</li>
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<li>Output dimensions: 192x256x128</li>
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<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
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<li>Discarded images: 0</li>
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</ul>
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</div>
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<div id="datatype-anat_suffix-dseg">
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<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S01/figures/sub-S01_dseg.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S01/figures/sub-S01_dseg.svg" target="_blank">sub-S01/figures/sub-S01_dseg.svg</a>
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</div>
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</div>
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<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
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<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S01/figures/sub-S01_space-MNI152NLin2009cAsym_T1w.svg">
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Problem loading figure sub-S01/figures/sub-S01_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S01/figures/sub-S01_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S01/figures/sub-S01_space-MNI152NLin2009cAsym_T1w.svg</a>
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</div>
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</div>
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</div>
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<div id="Functional">
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<h1 class="sub-report-title">Functional</h1>
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<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
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<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
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<ul class="elem-desc">
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<li>Repetition time (TR): 2.4s</li>
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<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
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<li>Slice timing correction: Not applied</li>
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<li>Susceptibility distortion correction: None</li>
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<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
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<li>Confounds collected: csf, csf_derivative1, csf_derivative1_power2, csf_power2, white_matter, white_matter_derivative1, white_matter_power2, white_matter_derivative1_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, t_comp_cor_04, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, a_comp_cor_84, a_comp_cor_85, a_comp_cor_86, a_comp_cor_87, a_comp_cor_88, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_derivative1_power2, trans_x_power2, trans_y, trans_y_derivative1, trans_y_derivative1_power2, trans_y_power2, trans_z, trans_z_derivative1, trans_z_derivative1_power2, trans_z_power2, rot_x, rot_x_derivative1, rot_x_derivative1_power2, rot_x_power2, rot_y, rot_y_derivative1, rot_y_derivative1_power2, rot_y_power2, rot_z, rot_z_derivative1, rot_z_derivative1_power2, rot_z_power2</li>
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<li>Non-steady-state volumes: 0</li>
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</ul>
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</div>
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<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
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<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
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<p class="elem-desc">
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The qform has been copied from sform.
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The difference in angle is 0.
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The difference in translation is 0.
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</p>
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</div>
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<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
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<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S01/figures/sub-S01_task-localizer_desc-flirtbbr_bold.svg">
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Problem loading figure sub-S01/figures/sub-S01_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S01/figures/sub-S01_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S01/figures/sub-S01_task-localizer_desc-flirtbbr_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
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<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S01/figures/sub-S01_task-localizer_desc-rois_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S01/figures/sub-S01_task-localizer_desc-rois_bold.svg" target="_blank">sub-S01/figures/sub-S01_task-localizer_desc-rois_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
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<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S01/figures/sub-S01_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S01/figures/sub-S01_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S01/figures/sub-S01_task-localizer_desc-compcorvar_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S01/figures/sub-S01_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S01/figures/sub-S01_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S01/figures/sub-S01_task-localizer_desc-carpetplot_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S01/figures/sub-S01_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S01/figures/sub-S01_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S01/figures/sub-S01_task-localizer_desc-confoundcorr_bold.svg</a>
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</div>
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</div>
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</div>
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<div id="About">
|
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<h1 class="sub-report-title">About</h1>
|
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S01 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-13 14:16:11 -0400</li>
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</ul>
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</div>
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</div>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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</li>
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</ul>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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+
<h3 id="references" class="unnumbered">References</h3>
|
| 239 |
+
<div id="refs" class="references">
|
| 240 |
+
<div id="ref-nilearn">
|
| 241 |
+
<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
|
| 242 |
+
</div>
|
| 243 |
+
<div id="ref-ants">
|
| 244 |
+
<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
|
| 245 |
+
</div>
|
| 246 |
+
<div id="ref-compcor">
|
| 247 |
+
<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
|
| 248 |
+
</div>
|
| 249 |
+
<div id="ref-fmriprep2">
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| 250 |
+
<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
|
| 251 |
+
</div>
|
| 252 |
+
<div id="ref-fmriprep1">
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| 253 |
+
<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
|
| 254 |
+
</div>
|
| 255 |
+
<div id="ref-mni152nlin2009casym">
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| 256 |
+
<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
|
| 257 |
+
</div>
|
| 258 |
+
<div id="ref-nipype1">
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| 259 |
+
<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
|
| 260 |
+
</div>
|
| 261 |
+
<div id="ref-nipype2">
|
| 262 |
+
<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
|
| 263 |
+
</div>
|
| 264 |
+
<div id="ref-bbr">
|
| 265 |
+
<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
|
| 266 |
+
</div>
|
| 267 |
+
<div id="ref-mcflirt">
|
| 268 |
+
<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
|
| 269 |
+
</div>
|
| 270 |
+
<div id="ref-flirt">
|
| 271 |
+
<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
|
| 272 |
+
</div>
|
| 273 |
+
<div id="ref-lanczos">
|
| 274 |
+
<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
|
| 275 |
+
</div>
|
| 276 |
+
<div id="ref-power_fd_dvars">
|
| 277 |
+
<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
|
| 278 |
+
</div>
|
| 279 |
+
<div id="ref-confounds_satterthwaite_2013">
|
| 280 |
+
<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
|
| 281 |
+
</div>
|
| 282 |
+
<div id="ref-n4">
|
| 283 |
+
<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
|
| 284 |
+
</div>
|
| 285 |
+
<div id="ref-fsl_fast">
|
| 286 |
+
<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
|
| 287 |
+
</div>
|
| 288 |
+
</div></div></div>
|
| 289 |
+
<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
|
| 290 |
+
Results included in this manuscript come from preprocessing
|
| 291 |
+
performed using *fMRIPrep* 20.0.6
|
| 292 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 293 |
+
which is based on *Nipype* 1.4.2
|
| 294 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
|
| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
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| 506 |
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title = {Machine learning for neuroimaging with scikit-learn},
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| 770 |
+
url = {https://www.frontiersin.org/articles/10.3389/fninf.2014.00014/full},
|
| 771 |
+
volume = 8,
|
| 772 |
+
year = 2014
|
| 773 |
+
}
|
| 774 |
+
|
| 775 |
+
@article{lanczos,
|
| 776 |
+
author = {Lanczos, C.},
|
| 777 |
+
doi = {10.1137/0701007},
|
| 778 |
+
issn = {0887-459X},
|
| 779 |
+
journal = {Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis},
|
| 780 |
+
number = 1,
|
| 781 |
+
pages = {76-85},
|
| 782 |
+
title = {Evaluation of Noisy Data},
|
| 783 |
+
url = {http://epubs.siam.org/doi/10.1137/0701007},
|
| 784 |
+
volume = 1,
|
| 785 |
+
year = 1964
|
| 786 |
+
}
|
| 787 |
+
|
| 788 |
+
@article{compcor,
|
| 789 |
+
author = {Behzadi, Yashar and Restom, Khaled and Liau, Joy and Liu, Thomas T.},
|
| 790 |
+
doi = {10.1016/j.neuroimage.2007.04.042},
|
| 791 |
+
issn = {1053-8119},
|
| 792 |
+
journal = {NeuroImage},
|
| 793 |
+
number = 1,
|
| 794 |
+
pages = {90-101},
|
| 795 |
+
title = {A component based noise correction method ({CompCor}) for {BOLD} and perfusion based fMRI},
|
| 796 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811907003837},
|
| 797 |
+
volume = 37,
|
| 798 |
+
year = 2007
|
| 799 |
+
}
|
| 800 |
+
|
| 801 |
+
@article{hcppipelines,
|
| 802 |
+
author = {Glasser, Matthew F. and Sotiropoulos, Stamatios N. and Wilson, J. Anthony and Coalson, Timothy S. and Fischl, Bruce and Andersson, Jesper L. and Xu, Junqian and Jbabdi, Saad and Webster, Matthew and Polimeni, Jonathan R. and Van Essen, David C. and Jenkinson, Mark},
|
| 803 |
+
doi = {10.1016/j.neuroimage.2013.04.127},
|
| 804 |
+
issn = {1053-8119},
|
| 805 |
+
journal = {NeuroImage},
|
| 806 |
+
pages = {105-124},
|
| 807 |
+
series = {Mapping the Connectome},
|
| 808 |
+
title = {The minimal preprocessing pipelines for the Human Connectome Project},
|
| 809 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913005053},
|
| 810 |
+
volume = 80,
|
| 811 |
+
year = 2013
|
| 812 |
+
}
|
| 813 |
+
|
| 814 |
+
@article{fs_template,
|
| 815 |
+
author = {Reuter, Martin and Rosas, Herminia Diana and Fischl, Bruce},
|
| 816 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
|
| 817 |
+
journal = {NeuroImage},
|
| 818 |
+
number = 4,
|
| 819 |
+
pages = {1181-1196},
|
| 820 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
|
| 821 |
+
volume = 53,
|
| 822 |
+
year = 2010
|
| 823 |
+
}
|
| 824 |
+
|
| 825 |
+
@article{afni,
|
| 826 |
+
author = {Cox, Robert W. and Hyde, James S.},
|
| 827 |
+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
|
| 828 |
+
journal = {NMR in Biomedicine},
|
| 829 |
+
number = {4-5},
|
| 830 |
+
pages = {171-178},
|
| 831 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 832 |
+
volume = 10,
|
| 833 |
+
year = 1997
|
| 834 |
+
}
|
| 835 |
+
|
| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
+
function toggle(id) {
|
| 859 |
+
var element = document.getElementById(id);
|
| 860 |
+
if(element.style.display == 'block')
|
| 861 |
+
element.style.display = 'none';
|
| 862 |
+
else
|
| 863 |
+
element.style.display = 'block';
|
| 864 |
+
}
|
| 865 |
+
</script>
|
| 866 |
+
</body>
|
| 867 |
+
</html>
|
derivatives/fmriprep/sub-S02.html
ADDED
|
@@ -0,0 +1,867 @@
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|
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|
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|
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body {
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|
| 39 |
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.boiler-html {
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font-family: "Bitstream Charter", "Georgia", Times;
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|
| 42 |
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|
| 43 |
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|
| 44 |
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}
|
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|
| 46 |
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div#boilerplate pre {
|
| 47 |
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margin: 20px 25px;
|
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|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
+
|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S02</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 192x256x128</li>
|
| 105 |
+
<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S02/figures/sub-S02_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S02/figures/sub-S02_dseg.svg" target="_blank">sub-S02/figures/sub-S02_dseg.svg</a>
|
| 115 |
+
</div>
|
| 116 |
+
|
| 117 |
+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S02/figures/sub-S02_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S02/figures/sub-S02_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S02/figures/sub-S02_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S02/figures/sub-S02_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_power2, csf_derivative1_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_power2, trans_x_derivative1_power2, trans_y, trans_y_derivative1, trans_y_power2, trans_y_derivative1_power2, trans_z, trans_z_derivative1, trans_z_power2, trans_z_derivative1_power2, rot_x, rot_x_derivative1, rot_x_power2, rot_x_derivative1_power2, rot_y, rot_y_derivative1, rot_y_derivative1_power2, rot_y_power2, rot_z, rot_z_derivative1, rot_z_derivative1_power2, rot_z_power2, motion_outlier00, motion_outlier01, motion_outlier02, motion_outlier03, motion_outlier04, motion_outlier05, motion_outlier06, motion_outlier07</li>
|
| 139 |
+
<li>Non-steady-state volumes: 0</li>
|
| 140 |
+
</ul>
|
| 141 |
+
</div>
|
| 142 |
+
<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
|
| 143 |
+
<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
|
| 144 |
+
<p class="elem-desc">
|
| 145 |
+
The qform has been copied from sform.
|
| 146 |
+
The difference in angle is 0.
|
| 147 |
+
The difference in translation is 0.
|
| 148 |
+
</p>
|
| 149 |
+
</div>
|
| 150 |
+
<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
|
| 151 |
+
<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S02/figures/sub-S02_task-localizer_desc-flirtbbr_bold.svg">
|
| 152 |
+
Problem loading figure sub-S02/figures/sub-S02_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 153 |
+
</div>
|
| 154 |
+
<div class="elem-filename">
|
| 155 |
+
Get figure file: <a href="./sub-S02/figures/sub-S02_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S02/figures/sub-S02_task-localizer_desc-flirtbbr_bold.svg</a>
|
| 156 |
+
</div>
|
| 157 |
+
|
| 158 |
+
</div>
|
| 159 |
+
<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
|
| 160 |
+
<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S02/figures/sub-S02_task-localizer_desc-rois_bold.svg" style="width: 100%" />
|
| 161 |
+
</div>
|
| 162 |
+
<div class="elem-filename">
|
| 163 |
+
Get figure file: <a href="./sub-S02/figures/sub-S02_task-localizer_desc-rois_bold.svg" target="_blank">sub-S02/figures/sub-S02_task-localizer_desc-rois_bold.svg</a>
|
| 164 |
+
</div>
|
| 165 |
+
|
| 166 |
+
</div>
|
| 167 |
+
<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
|
| 168 |
+
<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S02/figures/sub-S02_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
|
| 169 |
+
</div>
|
| 170 |
+
<div class="elem-filename">
|
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Get figure file: <a href="./sub-S02/figures/sub-S02_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S02/figures/sub-S02_task-localizer_desc-compcorvar_bold.svg</a>
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<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S02/figures/sub-S02_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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Get figure file: <a href="./sub-S02/figures/sub-S02_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S02/figures/sub-S02_task-localizer_desc-carpetplot_bold.svg</a>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S02/figures/sub-S02_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S02/figures/sub-S02_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S02/figures/sub-S02_task-localizer_desc-confoundcorr_bold.svg</a>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S02 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-13 15:44:42 -0400</li>
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</ul>
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</div>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
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<div id="ref-lanczos">
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<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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<div id="ref-power_fd_dvars">
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<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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<div id="ref-confounds_satterthwaite_2013">
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<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
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<div id="ref-n4">
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<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
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<div id="ref-fsl_fast">
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<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
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<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
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Results included in this manuscript come from preprocessing
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performed using *fMRIPrep* 20.0.6
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(@fmriprep1; @fmriprep2; RRID:SCR_016216),
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which is based on *Nipype* 1.4.2
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(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
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| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
|
| 506 |
+
<pre>@article{fmriprep1,
|
| 507 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
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| 508 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
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year = {2018},
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doi = {10.1038/s41592-018-0235-4},
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journal = {Nature Methods}
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author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
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title = {fMRIPrep},
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year = 2018,
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doi = {10.5281/zenodo.852659},
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publisher = {Zenodo},
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author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
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journal = {Frontiers in Neuroinformatics},
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pages = 13,
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title = {Nipype},
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year = 2018,
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doi = {10.5281/zenodo.596855},
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author = {Dale, Anders M. and Fischl, Bruce and Sereno, Martin I.},
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author = {Klein, Arno and Ghosh, Satrajit S. and Bao, Forrest S. and Giard, Joachim and Häme, Yrjö and Stavsky, Eliezer and Lee, Noah and Rossa, Brian and Reuter, Martin and Neto, Elias Chaibub and Keshavan, Anisha},
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url = {http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005350},
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| 585 |
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| 586 |
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title = {A {Probabilistic} {Atlas} of the {Human} {Brain}: {Theory} and {Rationale} for {Its} {Development}: {The} {International} {Consortium} for {Brain} {Mapping} ({ICBM})},
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author = {Mazziotta, John C. and Toga, Arthur W. and Evans, Alan and Fox, Peter and Lancaster, Jack},
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| 589 |
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| 590 |
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shorttitle = {A {Probabilistic} {Atlas} of the {Human} {Brain}},
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|
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|
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title = {Unbiased nonlinear average age-appropriate brain templates from birth to adulthood},
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author = {Fonov, VS and Evans, AC and McKinstry, RC and Almli, CR and Collins, DL},
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doi = {10.1016/S1053-8119(09)70884-5},
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title = {Methods to detect, characterize, and remove motion artifact in resting state fMRI},
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pages = {240--256},
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title = {{An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data}},
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}
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@article{nilearn,
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journal = {Frontiers in Neuroinformatics},
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+
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title = {Machine learning for neuroimaging with scikit-learn},
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year = 2014
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}
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@article{lanczos,
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+
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@article{compcor,
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+
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year = 2010
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}
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@article{afni,
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doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
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journal = {NMR in Biomedicine},
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+
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+
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}
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+
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| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
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| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
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function toggle(id) {
|
| 859 |
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var element = document.getElementById(id);
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if(element.style.display == 'block')
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| 863 |
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element.style.display = 'block';
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| 865 |
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|
| 866 |
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|
| 867 |
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|
derivatives/fmriprep/sub-S03.html
ADDED
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|
| 1 |
+
<?xml version="1.0" encoding="utf-8" ?>
|
| 2 |
+
<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
|
| 3 |
+
<html xmlns="http://www.w3.org/1999/xhtml" xml:lang="en" lang="en">
|
| 4 |
+
<head>
|
| 5 |
+
<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
|
| 6 |
+
<meta name="generator" content="Docutils 0.12: http://docutils.sourceforge.net/" />
|
| 7 |
+
<title></title>
|
| 8 |
+
<script src="https://code.jquery.com/jquery-3.3.1.slim.min.js" integrity="sha384-q8i/X+965DzO0rT7abK41JStQIAqVgRVzpbzo5smXKp4YfRvH+8abtTE1Pi6jizo" crossorigin="anonymous"></script>
|
| 9 |
+
<script src="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/js/bootstrap.min.js" integrity="sha384-ChfqqxuZUCnJSK3+MXmPNIyE6ZbWh2IMqE241rYiqJxyMiZ6OW/JmZQ5stwEULTy" crossorigin="anonymous"></script>
|
| 10 |
+
<link rel="stylesheet" href="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/css/bootstrap.min.css" integrity="sha384-MCw98/SFnGE8fJT3GXwEOngsV7Zt27NXFoaoApmYm81iuXoPkFOJwJ8ERdknLPMO" crossorigin="anonymous">
|
| 11 |
+
<style type="text/css">
|
| 12 |
+
.sub-report-title {}
|
| 13 |
+
.run-title {}
|
| 14 |
+
|
| 15 |
+
h1 { padding-top: 35px; }
|
| 16 |
+
h2 { padding-top: 20px; }
|
| 17 |
+
h3 { padding-top: 15px; }
|
| 18 |
+
|
| 19 |
+
.elem-desc {}
|
| 20 |
+
.elem-caption {
|
| 21 |
+
margin-top: 15px
|
| 22 |
+
margin-bottom: 0;
|
| 23 |
+
}
|
| 24 |
+
.elem-filename {}
|
| 25 |
+
|
| 26 |
+
div.elem-image {
|
| 27 |
+
width: 100%;
|
| 28 |
+
page-break-before:always;
|
| 29 |
+
}
|
| 30 |
+
|
| 31 |
+
.elem-image object.svg-reportlet {
|
| 32 |
+
width: 100%;
|
| 33 |
+
padding-bottom: 5px;
|
| 34 |
+
}
|
| 35 |
+
body {
|
| 36 |
+
padding: 65px 10px 10px;
|
| 37 |
+
}
|
| 38 |
+
|
| 39 |
+
.boiler-html {
|
| 40 |
+
font-family: "Bitstream Charter", "Georgia", Times;
|
| 41 |
+
margin: 20px 25px;
|
| 42 |
+
padding: 10px;
|
| 43 |
+
background-color: #F8F9FA;
|
| 44 |
+
}
|
| 45 |
+
|
| 46 |
+
div#boilerplate pre {
|
| 47 |
+
margin: 20px 25px;
|
| 48 |
+
padding: 10px;
|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
+
|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S03</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
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<li>Functional series: 1</li>
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<ul class="elem-desc">
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<li>Task: localizer (1 run)</li>
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</ul>
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<li>Standard output spaces: MNI152NLin2009cAsym</li>
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<li>Non-standard output spaces: </li>
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<li>FreeSurfer reconstruction: Not run</li>
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</ul>
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</div>
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</div>
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<div id="Anatomical">
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<h1 class="sub-report-title">Anatomical</h1>
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<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
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<h3 class="elem-title">Anatomical Conformation</h3>
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<ul class="elem-desc">
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<li>Input T1w images: 1</li>
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<li>Output orientation: RAS</li>
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<li>Output dimensions: 192x256x128</li>
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<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
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<li>Discarded images: 0</li>
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</ul>
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</div>
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<div id="datatype-anat_suffix-dseg">
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<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S03/figures/sub-S03_dseg.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S03/figures/sub-S03_dseg.svg" target="_blank">sub-S03/figures/sub-S03_dseg.svg</a>
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</div>
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</div>
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<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
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<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S03/figures/sub-S03_space-MNI152NLin2009cAsym_T1w.svg">
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Problem loading figure sub-S03/figures/sub-S03_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S03/figures/sub-S03_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S03/figures/sub-S03_space-MNI152NLin2009cAsym_T1w.svg</a>
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</div>
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</div>
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</div>
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<div id="Functional">
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<h1 class="sub-report-title">Functional</h1>
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<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
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<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
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<ul class="elem-desc">
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<li>Repetition time (TR): 2.4s</li>
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<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
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<li>Slice timing correction: Not applied</li>
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<li>Susceptibility distortion correction: None</li>
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<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
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<li>Confounds collected: csf, csf_derivative1, csf_power2, csf_derivative1_power2, white_matter, white_matter_derivative1, white_matter_power2, white_matter_derivative1_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, t_comp_cor_04, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_power2, trans_x_derivative1_power2, trans_y, trans_y_derivative1, trans_y_power2, trans_y_derivative1_power2, trans_z, trans_z_derivative1, trans_z_power2, trans_z_derivative1_power2, rot_x, rot_x_derivative1, rot_x_power2, rot_x_derivative1_power2, rot_y, rot_y_derivative1, rot_y_derivative1_power2, rot_y_power2, rot_z, rot_z_derivative1, rot_z_power2, rot_z_derivative1_power2, motion_outlier00, motion_outlier01, motion_outlier02, motion_outlier03</li>
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<li>Non-steady-state volumes: 0</li>
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| 140 |
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</ul>
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</div>
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<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
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<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
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<p class="elem-desc">
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The qform has been copied from sform.
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The difference in angle is 0.
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The difference in translation is 0.
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</p>
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</div>
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<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
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<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S03/figures/sub-S03_task-localizer_desc-flirtbbr_bold.svg">
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Problem loading figure sub-S03/figures/sub-S03_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S03/figures/sub-S03_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S03/figures/sub-S03_task-localizer_desc-flirtbbr_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
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<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S03/figures/sub-S03_task-localizer_desc-rois_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S03/figures/sub-S03_task-localizer_desc-rois_bold.svg" target="_blank">sub-S03/figures/sub-S03_task-localizer_desc-rois_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
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<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S03/figures/sub-S03_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S03/figures/sub-S03_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S03/figures/sub-S03_task-localizer_desc-compcorvar_bold.svg</a>
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</div>
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</div>
|
| 175 |
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<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S03/figures/sub-S03_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S03/figures/sub-S03_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S03/figures/sub-S03_task-localizer_desc-carpetplot_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
|
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
|
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+
Right: magnitude of the correlation between each confound time series and the
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+
mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S03/figures/sub-S03_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
|
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S03/figures/sub-S03_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S03/figures/sub-S03_task-localizer_desc-confoundcorr_bold.svg</a>
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</div>
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</div>
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</div>
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<div id="About">
|
| 199 |
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<h1 class="sub-report-title">About</h1>
|
| 200 |
+
<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S03 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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+
<li>Date preprocessed: 2020-05-13 16:44:59 -0400</li>
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</ul>
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</div>
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</div>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
|
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+
boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
|
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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</li>
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</ul>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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| 241 |
+
<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
|
| 242 |
+
</div>
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+
<div id="ref-ants">
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+
<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
|
| 245 |
+
</div>
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+
<div id="ref-compcor">
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+
<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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| 248 |
+
</div>
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| 249 |
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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+
</div>
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| 252 |
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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| 254 |
+
</div>
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<div id="ref-mni152nlin2009casym">
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+
<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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| 257 |
+
</div>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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| 260 |
+
</div>
|
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+
<div id="ref-nipype2">
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+
<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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+
</div>
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+
<div id="ref-bbr">
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+
<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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| 266 |
+
</div>
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+
<div id="ref-mcflirt">
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+
<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
|
| 269 |
+
</div>
|
| 270 |
+
<div id="ref-flirt">
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+
<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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| 272 |
+
</div>
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+
<div id="ref-lanczos">
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+
<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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| 275 |
+
</div>
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| 276 |
+
<div id="ref-power_fd_dvars">
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+
<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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| 278 |
+
</div>
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| 279 |
+
<div id="ref-confounds_satterthwaite_2013">
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| 280 |
+
<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
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| 281 |
+
</div>
|
| 282 |
+
<div id="ref-n4">
|
| 283 |
+
<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
|
| 284 |
+
</div>
|
| 285 |
+
<div id="ref-fsl_fast">
|
| 286 |
+
<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
|
| 287 |
+
</div>
|
| 288 |
+
</div></div></div>
|
| 289 |
+
<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
|
| 290 |
+
Results included in this manuscript come from preprocessing
|
| 291 |
+
performed using *fMRIPrep* 20.0.6
|
| 292 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 293 |
+
which is based on *Nipype* 1.4.2
|
| 294 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
|
| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
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<pre>@article{fmriprep1,
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year = 2014
|
| 773 |
+
}
|
| 774 |
+
|
| 775 |
+
@article{lanczos,
|
| 776 |
+
author = {Lanczos, C.},
|
| 777 |
+
doi = {10.1137/0701007},
|
| 778 |
+
issn = {0887-459X},
|
| 779 |
+
journal = {Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis},
|
| 780 |
+
number = 1,
|
| 781 |
+
pages = {76-85},
|
| 782 |
+
title = {Evaluation of Noisy Data},
|
| 783 |
+
url = {http://epubs.siam.org/doi/10.1137/0701007},
|
| 784 |
+
volume = 1,
|
| 785 |
+
year = 1964
|
| 786 |
+
}
|
| 787 |
+
|
| 788 |
+
@article{compcor,
|
| 789 |
+
author = {Behzadi, Yashar and Restom, Khaled and Liau, Joy and Liu, Thomas T.},
|
| 790 |
+
doi = {10.1016/j.neuroimage.2007.04.042},
|
| 791 |
+
issn = {1053-8119},
|
| 792 |
+
journal = {NeuroImage},
|
| 793 |
+
number = 1,
|
| 794 |
+
pages = {90-101},
|
| 795 |
+
title = {A component based noise correction method ({CompCor}) for {BOLD} and perfusion based fMRI},
|
| 796 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811907003837},
|
| 797 |
+
volume = 37,
|
| 798 |
+
year = 2007
|
| 799 |
+
}
|
| 800 |
+
|
| 801 |
+
@article{hcppipelines,
|
| 802 |
+
author = {Glasser, Matthew F. and Sotiropoulos, Stamatios N. and Wilson, J. Anthony and Coalson, Timothy S. and Fischl, Bruce and Andersson, Jesper L. and Xu, Junqian and Jbabdi, Saad and Webster, Matthew and Polimeni, Jonathan R. and Van Essen, David C. and Jenkinson, Mark},
|
| 803 |
+
doi = {10.1016/j.neuroimage.2013.04.127},
|
| 804 |
+
issn = {1053-8119},
|
| 805 |
+
journal = {NeuroImage},
|
| 806 |
+
pages = {105-124},
|
| 807 |
+
series = {Mapping the Connectome},
|
| 808 |
+
title = {The minimal preprocessing pipelines for the Human Connectome Project},
|
| 809 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913005053},
|
| 810 |
+
volume = 80,
|
| 811 |
+
year = 2013
|
| 812 |
+
}
|
| 813 |
+
|
| 814 |
+
@article{fs_template,
|
| 815 |
+
author = {Reuter, Martin and Rosas, Herminia Diana and Fischl, Bruce},
|
| 816 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
|
| 817 |
+
journal = {NeuroImage},
|
| 818 |
+
number = 4,
|
| 819 |
+
pages = {1181-1196},
|
| 820 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
|
| 821 |
+
volume = 53,
|
| 822 |
+
year = 2010
|
| 823 |
+
}
|
| 824 |
+
|
| 825 |
+
@article{afni,
|
| 826 |
+
author = {Cox, Robert W. and Hyde, James S.},
|
| 827 |
+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
|
| 828 |
+
journal = {NMR in Biomedicine},
|
| 829 |
+
number = {4-5},
|
| 830 |
+
pages = {171-178},
|
| 831 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 832 |
+
volume = 10,
|
| 833 |
+
year = 1997
|
| 834 |
+
}
|
| 835 |
+
|
| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
+
function toggle(id) {
|
| 859 |
+
var element = document.getElementById(id);
|
| 860 |
+
if(element.style.display == 'block')
|
| 861 |
+
element.style.display = 'none';
|
| 862 |
+
else
|
| 863 |
+
element.style.display = 'block';
|
| 864 |
+
}
|
| 865 |
+
</script>
|
| 866 |
+
</body>
|
| 867 |
+
</html>
|
derivatives/fmriprep/sub-S04.html
ADDED
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|
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|
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|
| 39 |
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|
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font-family: "Bitstream Charter", "Georgia", Times;
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|
| 42 |
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|
| 43 |
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|
| 44 |
+
}
|
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|
| 46 |
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div#boilerplate pre {
|
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margin: 20px 25px;
|
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|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
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|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S04</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 160x240x256</li>
|
| 105 |
+
<li>Output voxel size: 1.1mm x 1mm x 1mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S04/figures/sub-S04_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S04/figures/sub-S04_dseg.svg" target="_blank">sub-S04/figures/sub-S04_dseg.svg</a>
|
| 115 |
+
</div>
|
| 116 |
+
|
| 117 |
+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S04/figures/sub-S04_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S04/figures/sub-S04_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S04/figures/sub-S04_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S04/figures/sub-S04_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_derivative1_power2, csf_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, a_comp_cor_84, a_comp_cor_85, a_comp_cor_86, a_comp_cor_87, a_comp_cor_88, a_comp_cor_89, a_comp_cor_90, a_comp_cor_91, a_comp_cor_92, a_comp_cor_93, a_comp_cor_94, a_comp_cor_95, a_comp_cor_96, a_comp_cor_97, a_comp_cor_98, a_comp_cor_99, a_comp_cor_100, a_comp_cor_101, a_comp_cor_102, a_comp_cor_103, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_derivative1_power2, trans_x_power2, trans_y, trans_y_derivative1, trans_y_derivative1_power2, trans_y_power2, trans_z, trans_z_derivative1, trans_z_derivative1_power2, trans_z_power2, rot_x, rot_x_derivative1, rot_x_derivative1_power2, rot_x_power2, rot_y, rot_y_derivative1, rot_y_derivative1_power2, rot_y_power2, rot_z, rot_z_derivative1, rot_z_derivative1_power2, rot_z_power2</li>
|
| 139 |
+
<li>Non-steady-state volumes: 0</li>
|
| 140 |
+
</ul>
|
| 141 |
+
</div>
|
| 142 |
+
<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
|
| 143 |
+
<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S04/figures/sub-S04_task-localizer_desc-flirtbbr_bold.svg">
|
| 144 |
+
Problem loading figure sub-S04/figures/sub-S04_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 145 |
+
</div>
|
| 146 |
+
<div class="elem-filename">
|
| 147 |
+
Get figure file: <a href="./sub-S04/figures/sub-S04_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S04/figures/sub-S04_task-localizer_desc-flirtbbr_bold.svg</a>
|
| 148 |
+
</div>
|
| 149 |
+
|
| 150 |
+
</div>
|
| 151 |
+
<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
|
| 152 |
+
<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S04/figures/sub-S04_task-localizer_desc-rois_bold.svg" style="width: 100%" />
|
| 153 |
+
</div>
|
| 154 |
+
<div class="elem-filename">
|
| 155 |
+
Get figure file: <a href="./sub-S04/figures/sub-S04_task-localizer_desc-rois_bold.svg" target="_blank">sub-S04/figures/sub-S04_task-localizer_desc-rois_bold.svg</a>
|
| 156 |
+
</div>
|
| 157 |
+
|
| 158 |
+
</div>
|
| 159 |
+
<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
|
| 160 |
+
<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S04/figures/sub-S04_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
|
| 161 |
+
</div>
|
| 162 |
+
<div class="elem-filename">
|
| 163 |
+
Get figure file: <a href="./sub-S04/figures/sub-S04_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S04/figures/sub-S04_task-localizer_desc-compcorvar_bold.svg</a>
|
| 164 |
+
</div>
|
| 165 |
+
|
| 166 |
+
</div>
|
| 167 |
+
<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
|
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S04/figures/sub-S04_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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Get figure file: <a href="./sub-S04/figures/sub-S04_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S04/figures/sub-S04_task-localizer_desc-carpetplot_bold.svg</a>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S04/figures/sub-S04_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S04/figures/sub-S04_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S04/figures/sub-S04_task-localizer_desc-confoundcorr_bold.svg</a>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S04 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-13 17:13:23 -0400</li>
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</ul>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
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<div id="ref-lanczos">
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<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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<div id="ref-power_fd_dvars">
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<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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<div id="ref-confounds_satterthwaite_2013">
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<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
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<div id="ref-n4">
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<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
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<div id="ref-fsl_fast">
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<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
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<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
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Results included in this manuscript come from preprocessing
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+
performed using *fMRIPrep* 20.0.6
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(@fmriprep1; @fmriprep2; RRID:SCR_016216),
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which is based on *Nipype* 1.4.2
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(@nipype1; @nipype2; RRID:SCR_002502).
|
| 287 |
+
|
| 288 |
+
Anatomical data preprocessing
|
| 289 |
+
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| 290 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 291 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 292 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 293 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 294 |
+
as target template.
|
| 295 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 296 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 297 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 298 |
+
@fsl_fast].
|
| 299 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 300 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 301 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 302 |
+
The following template was selected for spatial normalization:
|
| 303 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 304 |
+
|
| 305 |
+
Functional data preprocessing
|
| 306 |
+
|
| 307 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 308 |
+
tasks and sessions), the following preprocessing was performed.
|
| 309 |
+
First, a reference volume and its skull-stripped version were generated
|
| 310 |
+
using a custom methodology of *fMRIPrep*.
|
| 311 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 312 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 313 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 314 |
+
cost-function.
|
| 315 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 316 |
+
for distortions remaining in the BOLD reference.
|
| 317 |
+
Head-motion parameters with respect to the BOLD reference
|
| 318 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 319 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 320 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 321 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 322 |
+
were resampled onto their original, native space by applying
|
| 323 |
+
the transforms to correct for head-motion.
|
| 324 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 325 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 326 |
+
The BOLD time-series were resampled into standard space,
|
| 327 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 328 |
+
First, a reference volume and its skull-stripped version were generated
|
| 329 |
+
using a custom methodology of *fMRIPrep*.
|
| 330 |
+
Several confounding time-series were calculated based on the
|
| 331 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 332 |
+
three region-wise global signals.
|
| 333 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 334 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 335 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 336 |
+
the whole-brain masks.
|
| 337 |
+
Additionally, a set of physiological regressors were extracted to
|
| 338 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 339 |
+
Principal components are estimated after high-pass filtering the
|
| 340 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 341 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 342 |
+
and anatomical (aCompCor).
|
| 343 |
+
tCompCor components are then calculated from the top 5% variable
|
| 344 |
+
voxels within a mask covering the subcortical regions.
|
| 345 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 346 |
+
which ensures it does not include cortical GM regions.
|
| 347 |
+
For aCompCor, components are calculated within the intersection of
|
| 348 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 349 |
+
in T1w space, after their projection to the native space of each
|
| 350 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 351 |
+
are also calculated separately within the WM and CSF masks.
|
| 352 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 353 |
+
values are retained, such that the retained components' time series are
|
| 354 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 355 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 356 |
+
consideration.
|
| 357 |
+
The head-motion estimates calculated in the correction step were also
|
| 358 |
+
placed within the corresponding confounds file.
|
| 359 |
+
The confound time series derived from head motion estimates and global
|
| 360 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 361 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 362 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 363 |
+
were annotated as motion outliers.
|
| 364 |
+
All resamplings can be performed with *a single interpolation
|
| 365 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 366 |
+
transform matrices, susceptibility distortion correction when available,
|
| 367 |
+
and co-registrations to anatomical and output spaces).
|
| 368 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 369 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 370 |
+
effects of other kernels [@lanczos].
|
| 371 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 372 |
+
(FreeSurfer).
|
| 373 |
+
|
| 374 |
+
|
| 375 |
+
Many internal operations of *fMRIPrep* use
|
| 376 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 377 |
+
mostly within the functional processing workflow.
|
| 378 |
+
For more details of the pipeline, see [the section corresponding
|
| 379 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 380 |
+
|
| 381 |
+
|
| 382 |
+
### Copyright Waiver
|
| 383 |
+
|
| 384 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 385 |
+
with the express intention that users should copy and paste this
|
| 386 |
+
text into their manuscripts *unchanged*.
|
| 387 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 388 |
+
|
| 389 |
+
### References
|
| 390 |
+
|
| 391 |
+
</pre>
|
| 392 |
+
</div>
|
| 393 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 394 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 395 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 396 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 397 |
+
|
| 398 |
+
\begin{description}
|
| 399 |
+
\item[Anatomical data preprocessing]
|
| 400 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 401 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 402 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 403 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 404 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 405 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 406 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 407 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 408 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 409 |
+
Volume-based spatial normalization to one standard space
|
| 410 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 411 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 412 |
+
of both T1w reference and the T1w template. The following template was
|
| 413 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 414 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 415 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 416 |
+
\item[Functional data preprocessing]
|
| 417 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 418 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 419 |
+
volume and its skull-stripped version were generated using a custom
|
| 420 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 421 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 422 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 423 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 424 |
+
was configured with nine degrees of freedom to account for distortions
|
| 425 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 426 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 427 |
+
rotation and translation parameters) are estimated before any
|
| 428 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 429 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 430 |
+
correction when applied) were resampled onto their original, native
|
| 431 |
+
space by applying the transforms to correct for head-motion. These
|
| 432 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 433 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 434 |
+
time-series were resampled into standard space, generating a
|
| 435 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 436 |
+
reference volume and its skull-stripped version were generated using a
|
| 437 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 438 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 439 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 440 |
+
DVARS are calculated for each functional run, both using their
|
| 441 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 442 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 443 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 444 |
+
physiological regressors were extracted to allow for component-based
|
| 445 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 446 |
+
components are estimated after high-pass filtering the
|
| 447 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 448 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 449 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 450 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 451 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 452 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 453 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 454 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 455 |
+
in T1w space, after their projection to the native space of each
|
| 456 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 457 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 458 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 459 |
+
singular values are retained, such that the retained components' time
|
| 460 |
+
series are sufficient to explain 50 percent of variance across the
|
| 461 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 462 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 463 |
+
the correction step were also placed within the corresponding confounds
|
| 464 |
+
file. The confound time series derived from head motion estimates and
|
| 465 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 466 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 467 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 468 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 469 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 470 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 471 |
+
distortion correction when available, and co-registrations to anatomical
|
| 472 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 473 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 474 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 475 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 476 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 477 |
+
\end{description}
|
| 478 |
+
|
| 479 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 480 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 481 |
+
processing workflow. For more details of the pipeline, see
|
| 482 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 483 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 484 |
+
|
| 485 |
+
\hypertarget{copyright-waiver}{%
|
| 486 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 487 |
+
|
| 488 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 489 |
+
the express intention that users should copy and paste this text into
|
| 490 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 491 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 492 |
+
|
| 493 |
+
\hypertarget{references}{%
|
| 494 |
+
\subsubsection{References}\label{references}}
|
| 495 |
+
|
| 496 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 497 |
+
<h3>Bibliography</h3>
|
| 498 |
+
<pre>@article{fmriprep1,
|
| 499 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
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| 500 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
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doi = {10.1038/s41592-018-0235-4},
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journal = {Nature Methods}
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author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
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title = {fMRIPrep},
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year = 2018,
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doi = {10.5281/zenodo.852659},
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publisher = {Zenodo},
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author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
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pages = 13,
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author = {Klein, Arno and Ghosh, Satrajit S. and Bao, Forrest S. and Giard, Joachim and Häme, Yrjö and Stavsky, Eliezer and Lee, Noah and Rossa, Brian and Reuter, Martin and Neto, Elias Chaibub and Keshavan, Anisha},
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title = {A {Probabilistic} {Atlas} of the {Human} {Brain}: {Theory} and {Rationale} for {Its} {Development}: {The} {International} {Consortium} for {Brain} {Mapping} ({ICBM})},
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author = {Mazziotta, John C. and Toga, Arthur W. and Evans, Alan and Fox, Peter and Lancaster, Jack},
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shorttitle = {A {Probabilistic} {Atlas} of the {Human} {Brain}},
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|
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title = {Unbiased nonlinear average age-appropriate brain templates from birth to adulthood},
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author = {Fonov, VS and Evans, AC and McKinstry, RC and Almli, CR and Collins, DL},
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author = {Evans, AC and Janke, AL and Collins, DL and Baillet, S},
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title = {Brain templates and atlases},
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doi = {10.1016/j.neuroimage.2012.01.024},
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journal = {NeuroImage},
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+
pages = {240--256},
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title = {{An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data}},
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title = {Machine learning for neuroimaging with scikit-learn},
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year = 2014
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}
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@article{lanczos,
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+
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+
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year = 2010
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}
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+
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+
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+
@article{posse_t2s,
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+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
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+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
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| 831 |
+
journal = {Magnetic Resonance in Medicine},
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| 832 |
+
number = 1,
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+
pages = {87-97},
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| 834 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 835 |
+
volume = 42,
|
| 836 |
+
year = 1999
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| 837 |
+
}
|
| 838 |
+
</pre>
|
| 839 |
+
</div>
|
| 840 |
+
</div>
|
| 841 |
+
</div>
|
| 842 |
+
|
| 843 |
+
<div id="errors">
|
| 844 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 845 |
+
<p>No errors to report!</p>
|
| 846 |
+
</div>
|
| 847 |
+
|
| 848 |
+
|
| 849 |
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<script type="text/javascript">
|
| 850 |
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function toggle(id) {
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| 851 |
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var element = document.getElementById(id);
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if(element.style.display == 'block')
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| 855 |
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element.style.display = 'block';
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| 857 |
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|
| 858 |
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|
| 859 |
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|
derivatives/fmriprep/sub-S05.html
ADDED
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|
| 1 |
+
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| 2 |
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| 3 |
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| 4 |
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<head>
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| 5 |
+
<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
|
| 6 |
+
<meta name="generator" content="Docutils 0.12: http://docutils.sourceforge.net/" />
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| 7 |
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<title></title>
|
| 8 |
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<script src="https://code.jquery.com/jquery-3.3.1.slim.min.js" integrity="sha384-q8i/X+965DzO0rT7abK41JStQIAqVgRVzpbzo5smXKp4YfRvH+8abtTE1Pi6jizo" crossorigin="anonymous"></script>
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| 9 |
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| 10 |
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<style type="text/css">
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| 12 |
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|
| 14 |
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|
| 15 |
+
h1 { padding-top: 35px; }
|
| 16 |
+
h2 { padding-top: 20px; }
|
| 17 |
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h3 { padding-top: 15px; }
|
| 18 |
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|
| 19 |
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| 20 |
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|
| 21 |
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margin-top: 15px
|
| 22 |
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margin-bottom: 0;
|
| 23 |
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}
|
| 24 |
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.elem-filename {}
|
| 25 |
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|
| 26 |
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div.elem-image {
|
| 27 |
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width: 100%;
|
| 28 |
+
page-break-before:always;
|
| 29 |
+
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|
| 30 |
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|
| 31 |
+
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|
| 32 |
+
width: 100%;
|
| 33 |
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padding-bottom: 5px;
|
| 34 |
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|
| 35 |
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body {
|
| 36 |
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padding: 65px 10px 10px;
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| 37 |
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| 38 |
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|
| 39 |
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| 40 |
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| 41 |
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| 42 |
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|
| 43 |
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background-color: #F8F9FA;
|
| 44 |
+
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|
| 45 |
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|
| 46 |
+
div#boilerplate pre {
|
| 47 |
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margin: 20px 25px;
|
| 48 |
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padding: 10px;
|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
+
|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
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</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S05</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
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<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
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<h3 class="elem-title">Anatomical Conformation</h3>
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<ul class="elem-desc">
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<li>Input T1w images: 1</li>
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<li>Output orientation: RAS</li>
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<li>Output dimensions: 160x240x256</li>
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<li>Output voxel size: 1.1mm x 1mm x 1mm</li>
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<li>Discarded images: 0</li>
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</ul>
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</div>
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<div id="datatype-anat_suffix-dseg">
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<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S05/figures/sub-S05_dseg.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S05/figures/sub-S05_dseg.svg" target="_blank">sub-S05/figures/sub-S05_dseg.svg</a>
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</div>
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</div>
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<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
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<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S05/figures/sub-S05_space-MNI152NLin2009cAsym_T1w.svg">
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Problem loading figure sub-S05/figures/sub-S05_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S05/figures/sub-S05_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S05/figures/sub-S05_space-MNI152NLin2009cAsym_T1w.svg</a>
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</div>
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<div id="Functional">
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<h1 class="sub-report-title">Functional</h1>
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<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
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<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
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<ul class="elem-desc">
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<li>Repetition time (TR): 2.4s</li>
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<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
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<li>Slice timing correction: Not applied</li>
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<li>Susceptibility distortion correction: None</li>
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<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
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<li>Confounds collected: csf, csf_derivative1, csf_derivative1_power2, csf_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_power2, global_signal_derivative1_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, a_comp_cor_84, a_comp_cor_85, a_comp_cor_86, a_comp_cor_87, a_comp_cor_88, a_comp_cor_89, a_comp_cor_90, a_comp_cor_91, a_comp_cor_92, a_comp_cor_93, a_comp_cor_94, a_comp_cor_95, a_comp_cor_96, a_comp_cor_97, a_comp_cor_98, a_comp_cor_99, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_derivative1_power2, trans_x_power2, trans_y, trans_y_derivative1, trans_y_power2, trans_y_derivative1_power2, trans_z, trans_z_derivative1, trans_z_power2, trans_z_derivative1_power2, rot_x, rot_x_derivative1, rot_x_power2, rot_x_derivative1_power2, rot_y, rot_y_derivative1, rot_y_power2, rot_y_derivative1_power2, rot_z, rot_z_derivative1, rot_z_power2, rot_z_derivative1_power2, motion_outlier00, motion_outlier01, motion_outlier02, motion_outlier03, motion_outlier04, motion_outlier05</li>
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<li>Non-steady-state volumes: 0</li>
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</ul>
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</div>
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<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
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<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S05/figures/sub-S05_task-localizer_desc-flirtbbr_bold.svg">
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Problem loading figure sub-S05/figures/sub-S05_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S05/figures/sub-S05_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S05/figures/sub-S05_task-localizer_desc-flirtbbr_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
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<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S05/figures/sub-S05_task-localizer_desc-rois_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S05/figures/sub-S05_task-localizer_desc-rois_bold.svg" target="_blank">sub-S05/figures/sub-S05_task-localizer_desc-rois_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
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<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S05/figures/sub-S05_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S05/figures/sub-S05_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S05/figures/sub-S05_task-localizer_desc-compcorvar_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S05/figures/sub-S05_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S05/figures/sub-S05_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S05/figures/sub-S05_task-localizer_desc-carpetplot_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S05/figures/sub-S05_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S05/figures/sub-S05_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S05/figures/sub-S05_task-localizer_desc-confoundcorr_bold.svg</a>
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</div>
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</div>
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</div>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
|
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S05 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-13 17:16:28 -0400</li>
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</ul>
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</div>
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</div>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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</div>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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| 239 |
+
<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
|
| 240 |
+
</div>
|
| 241 |
+
<div id="ref-fmriprep2">
|
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+
<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
|
| 243 |
+
</div>
|
| 244 |
+
<div id="ref-fmriprep1">
|
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+
<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
|
| 246 |
+
</div>
|
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+
<div id="ref-mni152nlin2009casym">
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| 248 |
+
<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
|
| 249 |
+
</div>
|
| 250 |
+
<div id="ref-nipype1">
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+
<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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| 252 |
+
</div>
|
| 253 |
+
<div id="ref-nipype2">
|
| 254 |
+
<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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+
</div>
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| 256 |
+
<div id="ref-bbr">
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+
<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
|
| 258 |
+
</div>
|
| 259 |
+
<div id="ref-mcflirt">
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| 260 |
+
<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
|
| 261 |
+
</div>
|
| 262 |
+
<div id="ref-flirt">
|
| 263 |
+
<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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| 264 |
+
</div>
|
| 265 |
+
<div id="ref-lanczos">
|
| 266 |
+
<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
|
| 267 |
+
</div>
|
| 268 |
+
<div id="ref-power_fd_dvars">
|
| 269 |
+
<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
|
| 270 |
+
</div>
|
| 271 |
+
<div id="ref-confounds_satterthwaite_2013">
|
| 272 |
+
<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
|
| 273 |
+
</div>
|
| 274 |
+
<div id="ref-n4">
|
| 275 |
+
<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
|
| 276 |
+
</div>
|
| 277 |
+
<div id="ref-fsl_fast">
|
| 278 |
+
<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
|
| 279 |
+
</div>
|
| 280 |
+
</div></div></div>
|
| 281 |
+
<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
|
| 282 |
+
Results included in this manuscript come from preprocessing
|
| 283 |
+
performed using *fMRIPrep* 20.0.6
|
| 284 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 285 |
+
which is based on *Nipype* 1.4.2
|
| 286 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 287 |
+
|
| 288 |
+
Anatomical data preprocessing
|
| 289 |
+
|
| 290 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 291 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 292 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 293 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 294 |
+
as target template.
|
| 295 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 296 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 297 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 298 |
+
@fsl_fast].
|
| 299 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 300 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 301 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 302 |
+
The following template was selected for spatial normalization:
|
| 303 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 304 |
+
|
| 305 |
+
Functional data preprocessing
|
| 306 |
+
|
| 307 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 308 |
+
tasks and sessions), the following preprocessing was performed.
|
| 309 |
+
First, a reference volume and its skull-stripped version were generated
|
| 310 |
+
using a custom methodology of *fMRIPrep*.
|
| 311 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 312 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 313 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 314 |
+
cost-function.
|
| 315 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 316 |
+
for distortions remaining in the BOLD reference.
|
| 317 |
+
Head-motion parameters with respect to the BOLD reference
|
| 318 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 319 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 320 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 321 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 322 |
+
were resampled onto their original, native space by applying
|
| 323 |
+
the transforms to correct for head-motion.
|
| 324 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 325 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 326 |
+
The BOLD time-series were resampled into standard space,
|
| 327 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 328 |
+
First, a reference volume and its skull-stripped version were generated
|
| 329 |
+
using a custom methodology of *fMRIPrep*.
|
| 330 |
+
Several confounding time-series were calculated based on the
|
| 331 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 332 |
+
three region-wise global signals.
|
| 333 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 334 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 335 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 336 |
+
the whole-brain masks.
|
| 337 |
+
Additionally, a set of physiological regressors were extracted to
|
| 338 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 339 |
+
Principal components are estimated after high-pass filtering the
|
| 340 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 341 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 342 |
+
and anatomical (aCompCor).
|
| 343 |
+
tCompCor components are then calculated from the top 5% variable
|
| 344 |
+
voxels within a mask covering the subcortical regions.
|
| 345 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 346 |
+
which ensures it does not include cortical GM regions.
|
| 347 |
+
For aCompCor, components are calculated within the intersection of
|
| 348 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 349 |
+
in T1w space, after their projection to the native space of each
|
| 350 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 351 |
+
are also calculated separately within the WM and CSF masks.
|
| 352 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 353 |
+
values are retained, such that the retained components' time series are
|
| 354 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 355 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 356 |
+
consideration.
|
| 357 |
+
The head-motion estimates calculated in the correction step were also
|
| 358 |
+
placed within the corresponding confounds file.
|
| 359 |
+
The confound time series derived from head motion estimates and global
|
| 360 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 361 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 362 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 363 |
+
were annotated as motion outliers.
|
| 364 |
+
All resamplings can be performed with *a single interpolation
|
| 365 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 366 |
+
transform matrices, susceptibility distortion correction when available,
|
| 367 |
+
and co-registrations to anatomical and output spaces).
|
| 368 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 369 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 370 |
+
effects of other kernels [@lanczos].
|
| 371 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 372 |
+
(FreeSurfer).
|
| 373 |
+
|
| 374 |
+
|
| 375 |
+
Many internal operations of *fMRIPrep* use
|
| 376 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 377 |
+
mostly within the functional processing workflow.
|
| 378 |
+
For more details of the pipeline, see [the section corresponding
|
| 379 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 380 |
+
|
| 381 |
+
|
| 382 |
+
### Copyright Waiver
|
| 383 |
+
|
| 384 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 385 |
+
with the express intention that users should copy and paste this
|
| 386 |
+
text into their manuscripts *unchanged*.
|
| 387 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 388 |
+
|
| 389 |
+
### References
|
| 390 |
+
|
| 391 |
+
</pre>
|
| 392 |
+
</div>
|
| 393 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 394 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 395 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 396 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 397 |
+
|
| 398 |
+
\begin{description}
|
| 399 |
+
\item[Anatomical data preprocessing]
|
| 400 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 401 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 402 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 403 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 404 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 405 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 406 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 407 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 408 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 409 |
+
Volume-based spatial normalization to one standard space
|
| 410 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 411 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 412 |
+
of both T1w reference and the T1w template. The following template was
|
| 413 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 414 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 415 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 416 |
+
\item[Functional data preprocessing]
|
| 417 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 418 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 419 |
+
volume and its skull-stripped version were generated using a custom
|
| 420 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 421 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 422 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 423 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 424 |
+
was configured with nine degrees of freedom to account for distortions
|
| 425 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 426 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 427 |
+
rotation and translation parameters) are estimated before any
|
| 428 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 429 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 430 |
+
correction when applied) were resampled onto their original, native
|
| 431 |
+
space by applying the transforms to correct for head-motion. These
|
| 432 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 433 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 434 |
+
time-series were resampled into standard space, generating a
|
| 435 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 436 |
+
reference volume and its skull-stripped version were generated using a
|
| 437 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 438 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 439 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 440 |
+
DVARS are calculated for each functional run, both using their
|
| 441 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 442 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 443 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 444 |
+
physiological regressors were extracted to allow for component-based
|
| 445 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 446 |
+
components are estimated after high-pass filtering the
|
| 447 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 448 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 449 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 450 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 451 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 452 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 453 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 454 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 455 |
+
in T1w space, after their projection to the native space of each
|
| 456 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 457 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 458 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 459 |
+
singular values are retained, such that the retained components' time
|
| 460 |
+
series are sufficient to explain 50 percent of variance across the
|
| 461 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 462 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 463 |
+
the correction step were also placed within the corresponding confounds
|
| 464 |
+
file. The confound time series derived from head motion estimates and
|
| 465 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 466 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 467 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 468 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 469 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 470 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 471 |
+
distortion correction when available, and co-registrations to anatomical
|
| 472 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 473 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 474 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 475 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 476 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 477 |
+
\end{description}
|
| 478 |
+
|
| 479 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 480 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 481 |
+
processing workflow. For more details of the pipeline, see
|
| 482 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 483 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 484 |
+
|
| 485 |
+
\hypertarget{copyright-waiver}{%
|
| 486 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 487 |
+
|
| 488 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 489 |
+
the express intention that users should copy and paste this text into
|
| 490 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 491 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
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| 492 |
+
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| 493 |
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\hypertarget{references}{%
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| 494 |
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\subsubsection{References}\label{references}}
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| 495 |
+
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| 496 |
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\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
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author = {Behzadi, Yashar and Restom, Khaled and Liau, Joy and Liu, Thomas T.},
|
| 782 |
+
doi = {10.1016/j.neuroimage.2007.04.042},
|
| 783 |
+
issn = {1053-8119},
|
| 784 |
+
journal = {NeuroImage},
|
| 785 |
+
number = 1,
|
| 786 |
+
pages = {90-101},
|
| 787 |
+
title = {A component based noise correction method ({CompCor}) for {BOLD} and perfusion based fMRI},
|
| 788 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811907003837},
|
| 789 |
+
volume = 37,
|
| 790 |
+
year = 2007
|
| 791 |
+
}
|
| 792 |
+
|
| 793 |
+
@article{hcppipelines,
|
| 794 |
+
author = {Glasser, Matthew F. and Sotiropoulos, Stamatios N. and Wilson, J. Anthony and Coalson, Timothy S. and Fischl, Bruce and Andersson, Jesper L. and Xu, Junqian and Jbabdi, Saad and Webster, Matthew and Polimeni, Jonathan R. and Van Essen, David C. and Jenkinson, Mark},
|
| 795 |
+
doi = {10.1016/j.neuroimage.2013.04.127},
|
| 796 |
+
issn = {1053-8119},
|
| 797 |
+
journal = {NeuroImage},
|
| 798 |
+
pages = {105-124},
|
| 799 |
+
series = {Mapping the Connectome},
|
| 800 |
+
title = {The minimal preprocessing pipelines for the Human Connectome Project},
|
| 801 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913005053},
|
| 802 |
+
volume = 80,
|
| 803 |
+
year = 2013
|
| 804 |
+
}
|
| 805 |
+
|
| 806 |
+
@article{fs_template,
|
| 807 |
+
author = {Reuter, Martin and Rosas, Herminia Diana and Fischl, Bruce},
|
| 808 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
|
| 809 |
+
journal = {NeuroImage},
|
| 810 |
+
number = 4,
|
| 811 |
+
pages = {1181-1196},
|
| 812 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
|
| 813 |
+
volume = 53,
|
| 814 |
+
year = 2010
|
| 815 |
+
}
|
| 816 |
+
|
| 817 |
+
@article{afni,
|
| 818 |
+
author = {Cox, Robert W. and Hyde, James S.},
|
| 819 |
+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
|
| 820 |
+
journal = {NMR in Biomedicine},
|
| 821 |
+
number = {4-5},
|
| 822 |
+
pages = {171-178},
|
| 823 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 824 |
+
volume = 10,
|
| 825 |
+
year = 1997
|
| 826 |
+
}
|
| 827 |
+
|
| 828 |
+
@article{posse_t2s,
|
| 829 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 830 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 831 |
+
journal = {Magnetic Resonance in Medicine},
|
| 832 |
+
number = 1,
|
| 833 |
+
pages = {87-97},
|
| 834 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 835 |
+
volume = 42,
|
| 836 |
+
year = 1999
|
| 837 |
+
}
|
| 838 |
+
</pre>
|
| 839 |
+
</div>
|
| 840 |
+
</div>
|
| 841 |
+
</div>
|
| 842 |
+
|
| 843 |
+
<div id="errors">
|
| 844 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 845 |
+
<p>No errors to report!</p>
|
| 846 |
+
</div>
|
| 847 |
+
|
| 848 |
+
|
| 849 |
+
<script type="text/javascript">
|
| 850 |
+
function toggle(id) {
|
| 851 |
+
var element = document.getElementById(id);
|
| 852 |
+
if(element.style.display == 'block')
|
| 853 |
+
element.style.display = 'none';
|
| 854 |
+
else
|
| 855 |
+
element.style.display = 'block';
|
| 856 |
+
}
|
| 857 |
+
</script>
|
| 858 |
+
</body>
|
| 859 |
+
</html>
|
derivatives/fmriprep/sub-S06.html
ADDED
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font-family: "Bitstream Charter", "Georgia", Times;
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|
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|
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}
|
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|
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div#boilerplate pre {
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margin: 20px 25px;
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|
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background-color: #F8F9FA;
|
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}
|
| 51 |
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|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
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+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S06</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 160x240x256</li>
|
| 105 |
+
<li>Output voxel size: 1.1mm x 1mm x 1mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S06/figures/sub-S06_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S06/figures/sub-S06_dseg.svg" target="_blank">sub-S06/figures/sub-S06_dseg.svg</a>
|
| 115 |
+
</div>
|
| 116 |
+
|
| 117 |
+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S06/figures/sub-S06_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S06/figures/sub-S06_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S06/figures/sub-S06_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S06/figures/sub-S06_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_derivative1_power2, csf_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, t_comp_cor_04, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, a_comp_cor_84, a_comp_cor_85, a_comp_cor_86, a_comp_cor_87, a_comp_cor_88, a_comp_cor_89, a_comp_cor_90, a_comp_cor_91, a_comp_cor_92, a_comp_cor_93, a_comp_cor_94, a_comp_cor_95, a_comp_cor_96, a_comp_cor_97, a_comp_cor_98, a_comp_cor_99, a_comp_cor_100, a_comp_cor_101, a_comp_cor_102, a_comp_cor_103, a_comp_cor_104, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_derivative1_power2, trans_x_power2, trans_y, trans_y_derivative1, trans_y_derivative1_power2, trans_y_power2, trans_z, trans_z_derivative1, trans_z_derivative1_power2, trans_z_power2, rot_x, rot_x_derivative1, rot_x_power2, rot_x_derivative1_power2, rot_y, rot_y_derivative1, rot_y_power2, rot_y_derivative1_power2, rot_z, rot_z_derivative1, rot_z_power2, rot_z_derivative1_power2, motion_outlier00, motion_outlier01, motion_outlier02</li>
|
| 139 |
+
<li>Non-steady-state volumes: 0</li>
|
| 140 |
+
</ul>
|
| 141 |
+
</div>
|
| 142 |
+
<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
|
| 143 |
+
<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S06/figures/sub-S06_task-localizer_desc-flirtbbr_bold.svg">
|
| 144 |
+
Problem loading figure sub-S06/figures/sub-S06_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 145 |
+
</div>
|
| 146 |
+
<div class="elem-filename">
|
| 147 |
+
Get figure file: <a href="./sub-S06/figures/sub-S06_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S06/figures/sub-S06_task-localizer_desc-flirtbbr_bold.svg</a>
|
| 148 |
+
</div>
|
| 149 |
+
|
| 150 |
+
</div>
|
| 151 |
+
<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
|
| 152 |
+
<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S06/figures/sub-S06_task-localizer_desc-rois_bold.svg" style="width: 100%" />
|
| 153 |
+
</div>
|
| 154 |
+
<div class="elem-filename">
|
| 155 |
+
Get figure file: <a href="./sub-S06/figures/sub-S06_task-localizer_desc-rois_bold.svg" target="_blank">sub-S06/figures/sub-S06_task-localizer_desc-rois_bold.svg</a>
|
| 156 |
+
</div>
|
| 157 |
+
|
| 158 |
+
</div>
|
| 159 |
+
<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
|
| 160 |
+
<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S06/figures/sub-S06_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
|
| 161 |
+
</div>
|
| 162 |
+
<div class="elem-filename">
|
| 163 |
+
Get figure file: <a href="./sub-S06/figures/sub-S06_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S06/figures/sub-S06_task-localizer_desc-compcorvar_bold.svg</a>
|
| 164 |
+
</div>
|
| 165 |
+
|
| 166 |
+
</div>
|
| 167 |
+
<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
|
| 168 |
+
<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S06/figures/sub-S06_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
|
| 169 |
+
</div>
|
| 170 |
+
<div class="elem-filename">
|
| 171 |
+
Get figure file: <a href="./sub-S06/figures/sub-S06_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S06/figures/sub-S06_task-localizer_desc-carpetplot_bold.svg</a>
|
| 172 |
+
</div>
|
| 173 |
+
|
| 174 |
+
</div>
|
| 175 |
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S06/figures/sub-S06_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S06/figures/sub-S06_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S06/figures/sub-S06_task-localizer_desc-confoundcorr_bold.svg</a>
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</div>
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</div>
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</div>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S06 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-13 17:19:02 -0400</li>
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</ul>
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</div>
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</div>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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</li>
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</ul>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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</div>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
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<div id="ref-lanczos">
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<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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</div>
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<div id="ref-power_fd_dvars">
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<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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</div>
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<div id="ref-confounds_satterthwaite_2013">
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<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
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</div>
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<div id="ref-n4">
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<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
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</div>
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<div id="ref-fsl_fast">
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<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
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</div></div></div>
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<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
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Results included in this manuscript come from preprocessing
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+
performed using *fMRIPrep* 20.0.6
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| 284 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
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+
which is based on *Nipype* 1.4.2
|
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+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 287 |
+
|
| 288 |
+
Anatomical data preprocessing
|
| 289 |
+
|
| 290 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 291 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 292 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 293 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 294 |
+
as target template.
|
| 295 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 296 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 297 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 298 |
+
@fsl_fast].
|
| 299 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 300 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 301 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 302 |
+
The following template was selected for spatial normalization:
|
| 303 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 304 |
+
|
| 305 |
+
Functional data preprocessing
|
| 306 |
+
|
| 307 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 308 |
+
tasks and sessions), the following preprocessing was performed.
|
| 309 |
+
First, a reference volume and its skull-stripped version were generated
|
| 310 |
+
using a custom methodology of *fMRIPrep*.
|
| 311 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 312 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 313 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 314 |
+
cost-function.
|
| 315 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 316 |
+
for distortions remaining in the BOLD reference.
|
| 317 |
+
Head-motion parameters with respect to the BOLD reference
|
| 318 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 319 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 320 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 321 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 322 |
+
were resampled onto their original, native space by applying
|
| 323 |
+
the transforms to correct for head-motion.
|
| 324 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 325 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 326 |
+
The BOLD time-series were resampled into standard space,
|
| 327 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 328 |
+
First, a reference volume and its skull-stripped version were generated
|
| 329 |
+
using a custom methodology of *fMRIPrep*.
|
| 330 |
+
Several confounding time-series were calculated based on the
|
| 331 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 332 |
+
three region-wise global signals.
|
| 333 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 334 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 335 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 336 |
+
the whole-brain masks.
|
| 337 |
+
Additionally, a set of physiological regressors were extracted to
|
| 338 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 339 |
+
Principal components are estimated after high-pass filtering the
|
| 340 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 341 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 342 |
+
and anatomical (aCompCor).
|
| 343 |
+
tCompCor components are then calculated from the top 5% variable
|
| 344 |
+
voxels within a mask covering the subcortical regions.
|
| 345 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 346 |
+
which ensures it does not include cortical GM regions.
|
| 347 |
+
For aCompCor, components are calculated within the intersection of
|
| 348 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 349 |
+
in T1w space, after their projection to the native space of each
|
| 350 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 351 |
+
are also calculated separately within the WM and CSF masks.
|
| 352 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 353 |
+
values are retained, such that the retained components' time series are
|
| 354 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 355 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 356 |
+
consideration.
|
| 357 |
+
The head-motion estimates calculated in the correction step were also
|
| 358 |
+
placed within the corresponding confounds file.
|
| 359 |
+
The confound time series derived from head motion estimates and global
|
| 360 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 361 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 362 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 363 |
+
were annotated as motion outliers.
|
| 364 |
+
All resamplings can be performed with *a single interpolation
|
| 365 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 366 |
+
transform matrices, susceptibility distortion correction when available,
|
| 367 |
+
and co-registrations to anatomical and output spaces).
|
| 368 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 369 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 370 |
+
effects of other kernels [@lanczos].
|
| 371 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 372 |
+
(FreeSurfer).
|
| 373 |
+
|
| 374 |
+
|
| 375 |
+
Many internal operations of *fMRIPrep* use
|
| 376 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 377 |
+
mostly within the functional processing workflow.
|
| 378 |
+
For more details of the pipeline, see [the section corresponding
|
| 379 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 380 |
+
|
| 381 |
+
|
| 382 |
+
### Copyright Waiver
|
| 383 |
+
|
| 384 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 385 |
+
with the express intention that users should copy and paste this
|
| 386 |
+
text into their manuscripts *unchanged*.
|
| 387 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 388 |
+
|
| 389 |
+
### References
|
| 390 |
+
|
| 391 |
+
</pre>
|
| 392 |
+
</div>
|
| 393 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 394 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 395 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 396 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 397 |
+
|
| 398 |
+
\begin{description}
|
| 399 |
+
\item[Anatomical data preprocessing]
|
| 400 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 401 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 402 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 403 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 404 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 405 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 406 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 407 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 408 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 409 |
+
Volume-based spatial normalization to one standard space
|
| 410 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 411 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 412 |
+
of both T1w reference and the T1w template. The following template was
|
| 413 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 414 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 415 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 416 |
+
\item[Functional data preprocessing]
|
| 417 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 418 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 419 |
+
volume and its skull-stripped version were generated using a custom
|
| 420 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 421 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 422 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 423 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 424 |
+
was configured with nine degrees of freedom to account for distortions
|
| 425 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 426 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 427 |
+
rotation and translation parameters) are estimated before any
|
| 428 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 429 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 430 |
+
correction when applied) were resampled onto their original, native
|
| 431 |
+
space by applying the transforms to correct for head-motion. These
|
| 432 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 433 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 434 |
+
time-series were resampled into standard space, generating a
|
| 435 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 436 |
+
reference volume and its skull-stripped version were generated using a
|
| 437 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 438 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 439 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 440 |
+
DVARS are calculated for each functional run, both using their
|
| 441 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 442 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 443 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 444 |
+
physiological regressors were extracted to allow for component-based
|
| 445 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 446 |
+
components are estimated after high-pass filtering the
|
| 447 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 448 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 449 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 450 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 451 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 452 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 453 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 454 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 455 |
+
in T1w space, after their projection to the native space of each
|
| 456 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 457 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 458 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 459 |
+
singular values are retained, such that the retained components' time
|
| 460 |
+
series are sufficient to explain 50 percent of variance across the
|
| 461 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 462 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 463 |
+
the correction step were also placed within the corresponding confounds
|
| 464 |
+
file. The confound time series derived from head motion estimates and
|
| 465 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 466 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 467 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 468 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 469 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 470 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 471 |
+
distortion correction when available, and co-registrations to anatomical
|
| 472 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 473 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 474 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 475 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 476 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 477 |
+
\end{description}
|
| 478 |
+
|
| 479 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 480 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 481 |
+
processing workflow. For more details of the pipeline, see
|
| 482 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 483 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 484 |
+
|
| 485 |
+
\hypertarget{copyright-waiver}{%
|
| 486 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 487 |
+
|
| 488 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 489 |
+
the express intention that users should copy and paste this text into
|
| 490 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 491 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 492 |
+
|
| 493 |
+
\hypertarget{references}{%
|
| 494 |
+
\subsubsection{References}\label{references}}
|
| 495 |
+
|
| 496 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 497 |
+
<h3>Bibliography</h3>
|
| 498 |
+
<pre>@article{fmriprep1,
|
| 499 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
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| 500 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
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| 501 |
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year = {2018},
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| 502 |
+
doi = {10.1038/s41592-018-0235-4},
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journal = {Nature Methods}
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}
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@article{fmriprep2,
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author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
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title = {fMRIPrep},
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year = 2018,
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doi = {10.5281/zenodo.852659},
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publisher = {Zenodo},
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author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
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pages = 13,
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title = {Unbiased nonlinear average age-appropriate brain templates from birth to adulthood},
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author = {Fonov, VS and Evans, AC and McKinstry, RC and Almli, CR and Collins, DL},
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author = {Avants, B.B. and Epstein, C.L. and Grossman, M. and Gee, J.C.},
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shorttitle = {Symmetric diffeomorphic image registration with cross-correlation},
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title = {Symmetric diffeomorphic image registration with cross-correlation: Evaluating automated labeling of elderly and neurodegenerative brain},
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url = {http://www.sciencedirect.com/science/article/pii/S1361841507000606},
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doi = {10.1016/S1361-8415(01)00036-6},
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pages = {825-841},
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title = {Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images},
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+
number = {Supplement C},
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+
pages = {267-277},
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+
shorttitle = {ICA-AROMA},
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+
title = {ICA-{AROMA}: A robust {ICA}-based strategy for removing motion artifacts from fMRI data},
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+
url = {http://www.sciencedirect.com/science/article/pii/S1053811915001822},
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+
volume = 112,
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+
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@article{power_fd_dvars,
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number = {Supplement C},
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+
pages = {320-341},
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+
title = {Methods to detect, characterize, and remove motion artifact in resting state fMRI},
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@article{confounds_satterthwaite_2013,
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doi = {10.1016/j.neuroimage.2012.08.052},
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+
journal = {NeuroImage},
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+
number = 1,
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+
pages = {240--256},
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title = {{An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data}},
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}
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@article{nilearn,
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+
journal = {Frontiers in Neuroinformatics},
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+
language = {English},
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+
title = {Machine learning for neuroimaging with scikit-learn},
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url = {https://www.frontiersin.org/articles/10.3389/fninf.2014.00014/full},
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+
volume = 8,
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+
year = 2014
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}
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+
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@article{lanczos,
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| 768 |
+
author = {Lanczos, C.},
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+
doi = {10.1137/0701007},
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+
issn = {0887-459X},
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+
journal = {Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis},
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+
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}
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@article{compcor,
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+
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volume = 37,
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@article{hcppipelines,
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+
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| 800 |
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title = {The minimal preprocessing pipelines for the Human Connectome Project},
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+
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@article{fs_template,
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+
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title = {Highly accurate inverse consistent registration: A robust approach},
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| 813 |
+
volume = 53,
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+
year = 2010
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}
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+
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@article{afni,
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author = {Cox, Robert W. and Hyde, James S.},
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+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
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journal = {NMR in Biomedicine},
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+
number = {4-5},
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+
pages = {171-178},
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title = {Software tools for analysis and visualization of fMRI data},
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| 824 |
+
volume = 10,
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+
year = 1997
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+
}
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| 827 |
+
|
| 828 |
+
@article{posse_t2s,
|
| 829 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
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| 830 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 831 |
+
journal = {Magnetic Resonance in Medicine},
|
| 832 |
+
number = 1,
|
| 833 |
+
pages = {87-97},
|
| 834 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 835 |
+
volume = 42,
|
| 836 |
+
year = 1999
|
| 837 |
+
}
|
| 838 |
+
</pre>
|
| 839 |
+
</div>
|
| 840 |
+
</div>
|
| 841 |
+
</div>
|
| 842 |
+
|
| 843 |
+
<div id="errors">
|
| 844 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 845 |
+
<p>No errors to report!</p>
|
| 846 |
+
</div>
|
| 847 |
+
|
| 848 |
+
|
| 849 |
+
<script type="text/javascript">
|
| 850 |
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function toggle(id) {
|
| 851 |
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var element = document.getElementById(id);
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| 852 |
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if(element.style.display == 'block')
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element.style.display = 'none';
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else
|
| 855 |
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element.style.display = 'block';
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| 856 |
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| 857 |
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</script>
|
| 858 |
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</body>
|
| 859 |
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</html>
|
derivatives/fmriprep/sub-S07.html
ADDED
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|
| 1 |
+
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| 2 |
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| 3 |
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| 4 |
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<head>
|
| 5 |
+
<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
|
| 6 |
+
<meta name="generator" content="Docutils 0.12: http://docutils.sourceforge.net/" />
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| 7 |
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<title></title>
|
| 8 |
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<script src="https://code.jquery.com/jquery-3.3.1.slim.min.js" integrity="sha384-q8i/X+965DzO0rT7abK41JStQIAqVgRVzpbzo5smXKp4YfRvH+8abtTE1Pi6jizo" crossorigin="anonymous"></script>
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| 9 |
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| 10 |
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<link rel="stylesheet" href="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/css/bootstrap.min.css" integrity="sha384-MCw98/SFnGE8fJT3GXwEOngsV7Zt27NXFoaoApmYm81iuXoPkFOJwJ8ERdknLPMO" crossorigin="anonymous">
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| 11 |
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<style type="text/css">
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| 12 |
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.sub-report-title {}
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| 13 |
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.run-title {}
|
| 14 |
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|
| 15 |
+
h1 { padding-top: 35px; }
|
| 16 |
+
h2 { padding-top: 20px; }
|
| 17 |
+
h3 { padding-top: 15px; }
|
| 18 |
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|
| 19 |
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.elem-desc {}
|
| 20 |
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.elem-caption {
|
| 21 |
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margin-top: 15px
|
| 22 |
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margin-bottom: 0;
|
| 23 |
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}
|
| 24 |
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.elem-filename {}
|
| 25 |
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|
| 26 |
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div.elem-image {
|
| 27 |
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width: 100%;
|
| 28 |
+
page-break-before:always;
|
| 29 |
+
}
|
| 30 |
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|
| 31 |
+
.elem-image object.svg-reportlet {
|
| 32 |
+
width: 100%;
|
| 33 |
+
padding-bottom: 5px;
|
| 34 |
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|
| 35 |
+
body {
|
| 36 |
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padding: 65px 10px 10px;
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| 37 |
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|
| 38 |
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|
| 39 |
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.boiler-html {
|
| 40 |
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font-family: "Bitstream Charter", "Georgia", Times;
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| 41 |
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margin: 20px 25px;
|
| 42 |
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padding: 10px;
|
| 43 |
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background-color: #F8F9FA;
|
| 44 |
+
}
|
| 45 |
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|
| 46 |
+
div#boilerplate pre {
|
| 47 |
+
margin: 20px 25px;
|
| 48 |
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padding: 10px;
|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
+
|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S07</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 160x240x256</li>
|
| 105 |
+
<li>Output voxel size: 1.1mm x 1mm x 1mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S07/figures/sub-S07_dseg.svg" style="width: 100%" />
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<div class="elem-filename">
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Get figure file: <a href="./sub-S07/figures/sub-S07_dseg.svg" target="_blank">sub-S07/figures/sub-S07_dseg.svg</a>
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<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
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<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S07/figures/sub-S07_space-MNI152NLin2009cAsym_T1w.svg">
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Problem loading figure sub-S07/figures/sub-S07_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S07/figures/sub-S07_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S07/figures/sub-S07_space-MNI152NLin2009cAsym_T1w.svg</a>
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<div id="Functional">
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<h1 class="sub-report-title">Functional</h1>
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<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
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<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
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<ul class="elem-desc">
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<li>Repetition time (TR): 2.4s</li>
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<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
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<li>Slice timing correction: Not applied</li>
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<li>Susceptibility distortion correction: None</li>
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<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
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<li>Confounds collected: csf, csf_derivative1, csf_power2, csf_derivative1_power2, white_matter, white_matter_derivative1, white_matter_power2, white_matter_derivative1_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, a_comp_cor_84, a_comp_cor_85, a_comp_cor_86, a_comp_cor_87, a_comp_cor_88, a_comp_cor_89, a_comp_cor_90, a_comp_cor_91, a_comp_cor_92, a_comp_cor_93, a_comp_cor_94, a_comp_cor_95, a_comp_cor_96, a_comp_cor_97, a_comp_cor_98, a_comp_cor_99, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_power2, trans_x_derivative1_power2, trans_y, trans_y_derivative1, trans_y_power2, trans_y_derivative1_power2, trans_z, trans_z_derivative1, trans_z_derivative1_power2, trans_z_power2, rot_x, rot_x_derivative1, rot_x_derivative1_power2, rot_x_power2, rot_y, rot_y_derivative1, rot_y_power2, rot_y_derivative1_power2, rot_z, rot_z_derivative1, rot_z_power2, rot_z_derivative1_power2</li>
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<li>Non-steady-state volumes: 0</li>
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</ul>
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</div>
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<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
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<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S07/figures/sub-S07_task-localizer_desc-flirtbbr_bold.svg">
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Problem loading figure sub-S07/figures/sub-S07_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
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Get figure file: <a href="./sub-S07/figures/sub-S07_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S07/figures/sub-S07_task-localizer_desc-flirtbbr_bold.svg</a>
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<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
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<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S07/figures/sub-S07_task-localizer_desc-rois_bold.svg" style="width: 100%" />
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<div class="elem-filename">
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Get figure file: <a href="./sub-S07/figures/sub-S07_task-localizer_desc-rois_bold.svg" target="_blank">sub-S07/figures/sub-S07_task-localizer_desc-rois_bold.svg</a>
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<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
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<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S07/figures/sub-S07_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
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Get figure file: <a href="./sub-S07/figures/sub-S07_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S07/figures/sub-S07_task-localizer_desc-compcorvar_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S07/figures/sub-S07_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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<div class="elem-filename">
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Get figure file: <a href="./sub-S07/figures/sub-S07_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S07/figures/sub-S07_task-localizer_desc-carpetplot_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S07/figures/sub-S07_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S07/figures/sub-S07_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S07/figures/sub-S07_task-localizer_desc-confoundcorr_bold.svg</a>
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</div>
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</div>
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</div>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S07 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-13 18:03:39 -0400</li>
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</ul>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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<div id="ref-fmriprep1">
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| 245 |
+
<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
|
| 246 |
+
</div>
|
| 247 |
+
<div id="ref-mni152nlin2009casym">
|
| 248 |
+
<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
|
| 249 |
+
</div>
|
| 250 |
+
<div id="ref-nipype1">
|
| 251 |
+
<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
|
| 252 |
+
</div>
|
| 253 |
+
<div id="ref-nipype2">
|
| 254 |
+
<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
|
| 255 |
+
</div>
|
| 256 |
+
<div id="ref-bbr">
|
| 257 |
+
<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
|
| 258 |
+
</div>
|
| 259 |
+
<div id="ref-mcflirt">
|
| 260 |
+
<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
|
| 261 |
+
</div>
|
| 262 |
+
<div id="ref-flirt">
|
| 263 |
+
<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
|
| 264 |
+
</div>
|
| 265 |
+
<div id="ref-lanczos">
|
| 266 |
+
<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
|
| 267 |
+
</div>
|
| 268 |
+
<div id="ref-power_fd_dvars">
|
| 269 |
+
<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
|
| 270 |
+
</div>
|
| 271 |
+
<div id="ref-confounds_satterthwaite_2013">
|
| 272 |
+
<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
|
| 273 |
+
</div>
|
| 274 |
+
<div id="ref-n4">
|
| 275 |
+
<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
|
| 276 |
+
</div>
|
| 277 |
+
<div id="ref-fsl_fast">
|
| 278 |
+
<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
|
| 279 |
+
</div>
|
| 280 |
+
</div></div></div>
|
| 281 |
+
<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
|
| 282 |
+
Results included in this manuscript come from preprocessing
|
| 283 |
+
performed using *fMRIPrep* 20.0.6
|
| 284 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 285 |
+
which is based on *Nipype* 1.4.2
|
| 286 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 287 |
+
|
| 288 |
+
Anatomical data preprocessing
|
| 289 |
+
|
| 290 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 291 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 292 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 293 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 294 |
+
as target template.
|
| 295 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 296 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 297 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 298 |
+
@fsl_fast].
|
| 299 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 300 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 301 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 302 |
+
The following template was selected for spatial normalization:
|
| 303 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 304 |
+
|
| 305 |
+
Functional data preprocessing
|
| 306 |
+
|
| 307 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 308 |
+
tasks and sessions), the following preprocessing was performed.
|
| 309 |
+
First, a reference volume and its skull-stripped version were generated
|
| 310 |
+
using a custom methodology of *fMRIPrep*.
|
| 311 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 312 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 313 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 314 |
+
cost-function.
|
| 315 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 316 |
+
for distortions remaining in the BOLD reference.
|
| 317 |
+
Head-motion parameters with respect to the BOLD reference
|
| 318 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 319 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 320 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 321 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 322 |
+
were resampled onto their original, native space by applying
|
| 323 |
+
the transforms to correct for head-motion.
|
| 324 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 325 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 326 |
+
The BOLD time-series were resampled into standard space,
|
| 327 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 328 |
+
First, a reference volume and its skull-stripped version were generated
|
| 329 |
+
using a custom methodology of *fMRIPrep*.
|
| 330 |
+
Several confounding time-series were calculated based on the
|
| 331 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 332 |
+
three region-wise global signals.
|
| 333 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 334 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 335 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 336 |
+
the whole-brain masks.
|
| 337 |
+
Additionally, a set of physiological regressors were extracted to
|
| 338 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 339 |
+
Principal components are estimated after high-pass filtering the
|
| 340 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 341 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 342 |
+
and anatomical (aCompCor).
|
| 343 |
+
tCompCor components are then calculated from the top 5% variable
|
| 344 |
+
voxels within a mask covering the subcortical regions.
|
| 345 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 346 |
+
which ensures it does not include cortical GM regions.
|
| 347 |
+
For aCompCor, components are calculated within the intersection of
|
| 348 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 349 |
+
in T1w space, after their projection to the native space of each
|
| 350 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 351 |
+
are also calculated separately within the WM and CSF masks.
|
| 352 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 353 |
+
values are retained, such that the retained components' time series are
|
| 354 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 355 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 356 |
+
consideration.
|
| 357 |
+
The head-motion estimates calculated in the correction step were also
|
| 358 |
+
placed within the corresponding confounds file.
|
| 359 |
+
The confound time series derived from head motion estimates and global
|
| 360 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 361 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 362 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 363 |
+
were annotated as motion outliers.
|
| 364 |
+
All resamplings can be performed with *a single interpolation
|
| 365 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 366 |
+
transform matrices, susceptibility distortion correction when available,
|
| 367 |
+
and co-registrations to anatomical and output spaces).
|
| 368 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 369 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 370 |
+
effects of other kernels [@lanczos].
|
| 371 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 372 |
+
(FreeSurfer).
|
| 373 |
+
|
| 374 |
+
|
| 375 |
+
Many internal operations of *fMRIPrep* use
|
| 376 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 377 |
+
mostly within the functional processing workflow.
|
| 378 |
+
For more details of the pipeline, see [the section corresponding
|
| 379 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 380 |
+
|
| 381 |
+
|
| 382 |
+
### Copyright Waiver
|
| 383 |
+
|
| 384 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 385 |
+
with the express intention that users should copy and paste this
|
| 386 |
+
text into their manuscripts *unchanged*.
|
| 387 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 388 |
+
|
| 389 |
+
### References
|
| 390 |
+
|
| 391 |
+
</pre>
|
| 392 |
+
</div>
|
| 393 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 394 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 395 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 396 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 397 |
+
|
| 398 |
+
\begin{description}
|
| 399 |
+
\item[Anatomical data preprocessing]
|
| 400 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 401 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 402 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 403 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 404 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 405 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 406 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 407 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 408 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 409 |
+
Volume-based spatial normalization to one standard space
|
| 410 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 411 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 412 |
+
of both T1w reference and the T1w template. The following template was
|
| 413 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 414 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 415 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 416 |
+
\item[Functional data preprocessing]
|
| 417 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 418 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 419 |
+
volume and its skull-stripped version were generated using a custom
|
| 420 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 421 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 422 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 423 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 424 |
+
was configured with nine degrees of freedom to account for distortions
|
| 425 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 426 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 427 |
+
rotation and translation parameters) are estimated before any
|
| 428 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 429 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 430 |
+
correction when applied) were resampled onto their original, native
|
| 431 |
+
space by applying the transforms to correct for head-motion. These
|
| 432 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 433 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 434 |
+
time-series were resampled into standard space, generating a
|
| 435 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 436 |
+
reference volume and its skull-stripped version were generated using a
|
| 437 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 438 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 439 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 440 |
+
DVARS are calculated for each functional run, both using their
|
| 441 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 442 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 443 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 444 |
+
physiological regressors were extracted to allow for component-based
|
| 445 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 446 |
+
components are estimated after high-pass filtering the
|
| 447 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 448 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 449 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 450 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 451 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 452 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 453 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 454 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 455 |
+
in T1w space, after their projection to the native space of each
|
| 456 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 457 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 458 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 459 |
+
singular values are retained, such that the retained components' time
|
| 460 |
+
series are sufficient to explain 50 percent of variance across the
|
| 461 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 462 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 463 |
+
the correction step were also placed within the corresponding confounds
|
| 464 |
+
file. The confound time series derived from head motion estimates and
|
| 465 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 466 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 467 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 468 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 469 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 470 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 471 |
+
distortion correction when available, and co-registrations to anatomical
|
| 472 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 473 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 474 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 475 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 476 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 477 |
+
\end{description}
|
| 478 |
+
|
| 479 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 480 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 481 |
+
processing workflow. For more details of the pipeline, see
|
| 482 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 483 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 484 |
+
|
| 485 |
+
\hypertarget{copyright-waiver}{%
|
| 486 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 487 |
+
|
| 488 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 489 |
+
the express intention that users should copy and paste this text into
|
| 490 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 491 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 492 |
+
|
| 493 |
+
\hypertarget{references}{%
|
| 494 |
+
\subsubsection{References}\label{references}}
|
| 495 |
+
|
| 496 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 497 |
+
<h3>Bibliography</h3>
|
| 498 |
+
<pre>@article{fmriprep1,
|
| 499 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
|
| 500 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
|
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author = {Glasser, Matthew F. and Sotiropoulos, Stamatios N. and Wilson, J. Anthony and Coalson, Timothy S. and Fischl, Bruce and Andersson, Jesper L. and Xu, Junqian and Jbabdi, Saad and Webster, Matthew and Polimeni, Jonathan R. and Van Essen, David C. and Jenkinson, Mark},
|
| 795 |
+
doi = {10.1016/j.neuroimage.2013.04.127},
|
| 796 |
+
issn = {1053-8119},
|
| 797 |
+
journal = {NeuroImage},
|
| 798 |
+
pages = {105-124},
|
| 799 |
+
series = {Mapping the Connectome},
|
| 800 |
+
title = {The minimal preprocessing pipelines for the Human Connectome Project},
|
| 801 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913005053},
|
| 802 |
+
volume = 80,
|
| 803 |
+
year = 2013
|
| 804 |
+
}
|
| 805 |
+
|
| 806 |
+
@article{fs_template,
|
| 807 |
+
author = {Reuter, Martin and Rosas, Herminia Diana and Fischl, Bruce},
|
| 808 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
|
| 809 |
+
journal = {NeuroImage},
|
| 810 |
+
number = 4,
|
| 811 |
+
pages = {1181-1196},
|
| 812 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
|
| 813 |
+
volume = 53,
|
| 814 |
+
year = 2010
|
| 815 |
+
}
|
| 816 |
+
|
| 817 |
+
@article{afni,
|
| 818 |
+
author = {Cox, Robert W. and Hyde, James S.},
|
| 819 |
+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
|
| 820 |
+
journal = {NMR in Biomedicine},
|
| 821 |
+
number = {4-5},
|
| 822 |
+
pages = {171-178},
|
| 823 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 824 |
+
volume = 10,
|
| 825 |
+
year = 1997
|
| 826 |
+
}
|
| 827 |
+
|
| 828 |
+
@article{posse_t2s,
|
| 829 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 830 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 831 |
+
journal = {Magnetic Resonance in Medicine},
|
| 832 |
+
number = 1,
|
| 833 |
+
pages = {87-97},
|
| 834 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 835 |
+
volume = 42,
|
| 836 |
+
year = 1999
|
| 837 |
+
}
|
| 838 |
+
</pre>
|
| 839 |
+
</div>
|
| 840 |
+
</div>
|
| 841 |
+
</div>
|
| 842 |
+
|
| 843 |
+
<div id="errors">
|
| 844 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 845 |
+
<p>No errors to report!</p>
|
| 846 |
+
</div>
|
| 847 |
+
|
| 848 |
+
|
| 849 |
+
<script type="text/javascript">
|
| 850 |
+
function toggle(id) {
|
| 851 |
+
var element = document.getElementById(id);
|
| 852 |
+
if(element.style.display == 'block')
|
| 853 |
+
element.style.display = 'none';
|
| 854 |
+
else
|
| 855 |
+
element.style.display = 'block';
|
| 856 |
+
}
|
| 857 |
+
</script>
|
| 858 |
+
</body>
|
| 859 |
+
</html>
|
derivatives/fmriprep/sub-S08.html
ADDED
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font-family: "Bitstream Charter", "Georgia", Times;
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background-color: #F8F9FA;
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}
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div#boilerplate pre {
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margin: 20px 25px;
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background-color: #F8F9FA;
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}
|
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|
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+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
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}
|
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+
</style>
|
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+
</head>
|
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+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S08</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 176x256x256</li>
|
| 105 |
+
<li>Output voxel size: 1mm x 1mm x 1mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S08/figures/sub-S08_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S08/figures/sub-S08_dseg.svg" target="_blank">sub-S08/figures/sub-S08_dseg.svg</a>
|
| 115 |
+
</div>
|
| 116 |
+
|
| 117 |
+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S08/figures/sub-S08_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S08/figures/sub-S08_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S08/figures/sub-S08_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S08/figures/sub-S08_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_power2, csf_derivative1_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, a_comp_cor_84, a_comp_cor_85, a_comp_cor_86, a_comp_cor_87, a_comp_cor_88, a_comp_cor_89, a_comp_cor_90, a_comp_cor_91, a_comp_cor_92, a_comp_cor_93, a_comp_cor_94, a_comp_cor_95, a_comp_cor_96, a_comp_cor_97, a_comp_cor_98, a_comp_cor_99, a_comp_cor_100, a_comp_cor_101, a_comp_cor_102, a_comp_cor_103, a_comp_cor_104, a_comp_cor_105, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_derivative1_power2, trans_x_power2, trans_y, trans_y_derivative1, trans_y_derivative1_power2, trans_y_power2, trans_z, trans_z_derivative1, trans_z_power2, trans_z_derivative1_power2, rot_x, rot_x_derivative1, rot_x_power2, rot_x_derivative1_power2, rot_y, rot_y_derivative1, rot_y_power2, rot_y_derivative1_power2, rot_z, rot_z_derivative1, rot_z_power2, rot_z_derivative1_power2, motion_outlier00</li>
|
| 139 |
+
<li>Non-steady-state volumes: 0</li>
|
| 140 |
+
</ul>
|
| 141 |
+
</div>
|
| 142 |
+
<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
|
| 143 |
+
<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S08/figures/sub-S08_task-localizer_desc-flirtbbr_bold.svg">
|
| 144 |
+
Problem loading figure sub-S08/figures/sub-S08_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 145 |
+
</div>
|
| 146 |
+
<div class="elem-filename">
|
| 147 |
+
Get figure file: <a href="./sub-S08/figures/sub-S08_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S08/figures/sub-S08_task-localizer_desc-flirtbbr_bold.svg</a>
|
| 148 |
+
</div>
|
| 149 |
+
|
| 150 |
+
</div>
|
| 151 |
+
<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
|
| 152 |
+
<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S08/figures/sub-S08_task-localizer_desc-rois_bold.svg" style="width: 100%" />
|
| 153 |
+
</div>
|
| 154 |
+
<div class="elem-filename">
|
| 155 |
+
Get figure file: <a href="./sub-S08/figures/sub-S08_task-localizer_desc-rois_bold.svg" target="_blank">sub-S08/figures/sub-S08_task-localizer_desc-rois_bold.svg</a>
|
| 156 |
+
</div>
|
| 157 |
+
|
| 158 |
+
</div>
|
| 159 |
+
<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
|
| 160 |
+
<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S08/figures/sub-S08_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
|
| 161 |
+
</div>
|
| 162 |
+
<div class="elem-filename">
|
| 163 |
+
Get figure file: <a href="./sub-S08/figures/sub-S08_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S08/figures/sub-S08_task-localizer_desc-compcorvar_bold.svg</a>
|
| 164 |
+
</div>
|
| 165 |
+
|
| 166 |
+
</div>
|
| 167 |
+
<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
|
| 168 |
+
<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S08/figures/sub-S08_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
|
| 169 |
+
</div>
|
| 170 |
+
<div class="elem-filename">
|
| 171 |
+
Get figure file: <a href="./sub-S08/figures/sub-S08_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S08/figures/sub-S08_task-localizer_desc-carpetplot_bold.svg</a>
|
| 172 |
+
</div>
|
| 173 |
+
|
| 174 |
+
</div>
|
| 175 |
+
<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
|
| 176 |
+
<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
|
| 177 |
+
(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
|
| 178 |
+
Right: magnitude of the correlation between each confound time series and the
|
| 179 |
+
mean global signal. Strong correlations might be indicative of partial volume
|
| 180 |
+
effects and can inform decisions about feature orthogonalization prior to
|
| 181 |
+
confound regression.
|
| 182 |
+
</p> <img class="svg-reportlet" src="./sub-S08/figures/sub-S08_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
|
| 183 |
+
</div>
|
| 184 |
+
<div class="elem-filename">
|
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Get figure file: <a href="./sub-S08/figures/sub-S08_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S08/figures/sub-S08_task-localizer_desc-confoundcorr_bold.svg</a>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S08 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-13 18:20:36 -0400</li>
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</ul>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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</div>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
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<div id="ref-lanczos">
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<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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</div>
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<div id="ref-power_fd_dvars">
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<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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</div>
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<div id="ref-confounds_satterthwaite_2013">
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<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
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</div>
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<div id="ref-n4">
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<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
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</div>
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<div id="ref-fsl_fast">
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<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
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</div></div></div>
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<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
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Results included in this manuscript come from preprocessing
|
| 283 |
+
performed using *fMRIPrep* 20.0.6
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| 284 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
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+
which is based on *Nipype* 1.4.2
|
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+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 287 |
+
|
| 288 |
+
Anatomical data preprocessing
|
| 289 |
+
|
| 290 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 291 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 292 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 293 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 294 |
+
as target template.
|
| 295 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 296 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 297 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 298 |
+
@fsl_fast].
|
| 299 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 300 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 301 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 302 |
+
The following template was selected for spatial normalization:
|
| 303 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 304 |
+
|
| 305 |
+
Functional data preprocessing
|
| 306 |
+
|
| 307 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 308 |
+
tasks and sessions), the following preprocessing was performed.
|
| 309 |
+
First, a reference volume and its skull-stripped version were generated
|
| 310 |
+
using a custom methodology of *fMRIPrep*.
|
| 311 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 312 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 313 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 314 |
+
cost-function.
|
| 315 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 316 |
+
for distortions remaining in the BOLD reference.
|
| 317 |
+
Head-motion parameters with respect to the BOLD reference
|
| 318 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 319 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 320 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 321 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 322 |
+
were resampled onto their original, native space by applying
|
| 323 |
+
the transforms to correct for head-motion.
|
| 324 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 325 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 326 |
+
The BOLD time-series were resampled into standard space,
|
| 327 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 328 |
+
First, a reference volume and its skull-stripped version were generated
|
| 329 |
+
using a custom methodology of *fMRIPrep*.
|
| 330 |
+
Several confounding time-series were calculated based on the
|
| 331 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 332 |
+
three region-wise global signals.
|
| 333 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 334 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 335 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 336 |
+
the whole-brain masks.
|
| 337 |
+
Additionally, a set of physiological regressors were extracted to
|
| 338 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 339 |
+
Principal components are estimated after high-pass filtering the
|
| 340 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 341 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 342 |
+
and anatomical (aCompCor).
|
| 343 |
+
tCompCor components are then calculated from the top 5% variable
|
| 344 |
+
voxels within a mask covering the subcortical regions.
|
| 345 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 346 |
+
which ensures it does not include cortical GM regions.
|
| 347 |
+
For aCompCor, components are calculated within the intersection of
|
| 348 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 349 |
+
in T1w space, after their projection to the native space of each
|
| 350 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 351 |
+
are also calculated separately within the WM and CSF masks.
|
| 352 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 353 |
+
values are retained, such that the retained components' time series are
|
| 354 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 355 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 356 |
+
consideration.
|
| 357 |
+
The head-motion estimates calculated in the correction step were also
|
| 358 |
+
placed within the corresponding confounds file.
|
| 359 |
+
The confound time series derived from head motion estimates and global
|
| 360 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 361 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 362 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 363 |
+
were annotated as motion outliers.
|
| 364 |
+
All resamplings can be performed with *a single interpolation
|
| 365 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 366 |
+
transform matrices, susceptibility distortion correction when available,
|
| 367 |
+
and co-registrations to anatomical and output spaces).
|
| 368 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 369 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 370 |
+
effects of other kernels [@lanczos].
|
| 371 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 372 |
+
(FreeSurfer).
|
| 373 |
+
|
| 374 |
+
|
| 375 |
+
Many internal operations of *fMRIPrep* use
|
| 376 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 377 |
+
mostly within the functional processing workflow.
|
| 378 |
+
For more details of the pipeline, see [the section corresponding
|
| 379 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 380 |
+
|
| 381 |
+
|
| 382 |
+
### Copyright Waiver
|
| 383 |
+
|
| 384 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 385 |
+
with the express intention that users should copy and paste this
|
| 386 |
+
text into their manuscripts *unchanged*.
|
| 387 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 388 |
+
|
| 389 |
+
### References
|
| 390 |
+
|
| 391 |
+
</pre>
|
| 392 |
+
</div>
|
| 393 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 394 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 395 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 396 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 397 |
+
|
| 398 |
+
\begin{description}
|
| 399 |
+
\item[Anatomical data preprocessing]
|
| 400 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 401 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 402 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 403 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 404 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 405 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 406 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 407 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 408 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 409 |
+
Volume-based spatial normalization to one standard space
|
| 410 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 411 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 412 |
+
of both T1w reference and the T1w template. The following template was
|
| 413 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 414 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 415 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 416 |
+
\item[Functional data preprocessing]
|
| 417 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 418 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 419 |
+
volume and its skull-stripped version were generated using a custom
|
| 420 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 421 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 422 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 423 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 424 |
+
was configured with nine degrees of freedom to account for distortions
|
| 425 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 426 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 427 |
+
rotation and translation parameters) are estimated before any
|
| 428 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 429 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 430 |
+
correction when applied) were resampled onto their original, native
|
| 431 |
+
space by applying the transforms to correct for head-motion. These
|
| 432 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 433 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 434 |
+
time-series were resampled into standard space, generating a
|
| 435 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 436 |
+
reference volume and its skull-stripped version were generated using a
|
| 437 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 438 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 439 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 440 |
+
DVARS are calculated for each functional run, both using their
|
| 441 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 442 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 443 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 444 |
+
physiological regressors were extracted to allow for component-based
|
| 445 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 446 |
+
components are estimated after high-pass filtering the
|
| 447 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 448 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 449 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 450 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 451 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 452 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 453 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 454 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 455 |
+
in T1w space, after their projection to the native space of each
|
| 456 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 457 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 458 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 459 |
+
singular values are retained, such that the retained components' time
|
| 460 |
+
series are sufficient to explain 50 percent of variance across the
|
| 461 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 462 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 463 |
+
the correction step were also placed within the corresponding confounds
|
| 464 |
+
file. The confound time series derived from head motion estimates and
|
| 465 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 466 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 467 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 468 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 469 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 470 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 471 |
+
distortion correction when available, and co-registrations to anatomical
|
| 472 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 473 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 474 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 475 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 476 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 477 |
+
\end{description}
|
| 478 |
+
|
| 479 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 480 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 481 |
+
processing workflow. For more details of the pipeline, see
|
| 482 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 483 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 484 |
+
|
| 485 |
+
\hypertarget{copyright-waiver}{%
|
| 486 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 487 |
+
|
| 488 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 489 |
+
the express intention that users should copy and paste this text into
|
| 490 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 491 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 492 |
+
|
| 493 |
+
\hypertarget{references}{%
|
| 494 |
+
\subsubsection{References}\label{references}}
|
| 495 |
+
|
| 496 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 497 |
+
<h3>Bibliography</h3>
|
| 498 |
+
<pre>@article{fmriprep1,
|
| 499 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
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| 500 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
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| 501 |
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+
doi = {10.1038/s41592-018-0235-4},
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journal = {Nature Methods}
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year = 2018,
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author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
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+
volume = 11,
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+
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+
}
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@phdthesis{fieldmapless2,
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address = {Berlin},
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author = {Huntenburg, Julia M.},
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language = {eng},
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school = {Freie Universität},
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title = {Evaluating nonlinear coregistration of {BOLD} {EPI} and T1w images},
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number = 3,
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+
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@article{flirt,
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+
volume = {5},
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issn = {1361-8415},
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url = {http://www.sciencedirect.com/science/article/pii/S1361841501000366},
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doi = {10.1016/S1361-8415(01)00036-6},
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+
author = {Jenkinson, Mark and Smith, Stephen},
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+
year = {2001},
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+
keywords = {Affine transformation, flirt, fsl, Global optimisation, Multi-resolution search, Multimodal registration, Robustness},
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+
pages = {143--156}
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}
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+
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@article{mcflirt,
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author = {Jenkinson, Mark and Bannister, Peter and Brady, Michael and Smith, Stephen},
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doi = {10.1006/nimg.2002.1132},
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+
issn = {1053-8119},
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+
journal = {NeuroImage},
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+
number = 2,
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| 695 |
+
pages = {825-841},
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+
title = {Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images},
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+
url = {http://www.sciencedirect.com/science/article/pii/S1053811902911328},
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+
volume = 17,
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| 699 |
+
year = 2002
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}
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@article{bbr,
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author = {Greve, Douglas N and Fischl, Bruce},
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| 704 |
+
doi = {10.1016/j.neuroimage.2009.06.060},
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| 705 |
+
issn = {1095-9572},
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+
journal = {NeuroImage},
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+
number = 1,
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| 708 |
+
pages = {63-72},
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+
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+
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}
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@article{aroma,
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+
doi = {10.1016/j.neuroimage.2015.02.064},
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+
issn = {1053-8119},
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| 718 |
+
journal = {NeuroImage},
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| 719 |
+
number = {Supplement C},
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| 720 |
+
pages = {267-277},
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| 721 |
+
shorttitle = {ICA-AROMA},
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| 722 |
+
title = {ICA-{AROMA}: A robust {ICA}-based strategy for removing motion artifacts from fMRI data},
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| 723 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811915001822},
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| 724 |
+
volume = 112,
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| 725 |
+
year = 2015
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| 726 |
+
}
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+
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+
@article{power_fd_dvars,
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| 729 |
+
author = {Power, Jonathan D. and Mitra, Anish and Laumann, Timothy O. and Snyder, Abraham Z. and Schlaggar, Bradley L. and Petersen, Steven E.},
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+
doi = {10.1016/j.neuroimage.2013.08.048},
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+
issn = {1053-8119},
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+
journal = {NeuroImage},
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+
number = {Supplement C},
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| 734 |
+
pages = {320-341},
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+
title = {Methods to detect, characterize, and remove motion artifact in resting state fMRI},
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+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913009117},
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+
volume = 84,
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+
year = 2014
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+
}
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+
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+
@article{confounds_satterthwaite_2013,
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+
author = {Satterthwaite, Theodore D. and Elliott, Mark A. and Gerraty, Raphael T. and Ruparel, Kosha and Loughead, James and Calkins, Monica E. and Eickhoff, Simon B. and Hakonarson, Hakon and Gur, Ruben C. and Gur, Raquel E. and Wolf, Daniel H.},
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+
doi = {10.1016/j.neuroimage.2012.08.052},
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+
issn = {10538119},
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| 745 |
+
journal = {NeuroImage},
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| 746 |
+
number = 1,
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| 747 |
+
pages = {240--256},
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| 748 |
+
title = {{An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data}},
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+
url = {http://linkinghub.elsevier.com/retrieve/pii/S1053811912008609},
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+
volume = 64,
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+
year = 2013
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+
}
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+
@article{nilearn,
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+
author = {Abraham, Alexandre and Pedregosa, Fabian and Eickenberg, Michael and Gervais, Philippe and Mueller, Andreas and Kossaifi, Jean and Gramfort, Alexandre and Thirion, Bertrand and Varoquaux, Gael},
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+
doi = {10.3389/fninf.2014.00014},
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+
issn = {1662-5196},
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+
journal = {Frontiers in Neuroinformatics},
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| 760 |
+
language = {English},
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| 761 |
+
title = {Machine learning for neuroimaging with scikit-learn},
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| 762 |
+
url = {https://www.frontiersin.org/articles/10.3389/fninf.2014.00014/full},
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| 763 |
+
volume = 8,
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| 764 |
+
year = 2014
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| 765 |
+
}
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| 766 |
+
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| 767 |
+
@article{lanczos,
|
| 768 |
+
author = {Lanczos, C.},
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| 769 |
+
doi = {10.1137/0701007},
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| 770 |
+
issn = {0887-459X},
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| 771 |
+
journal = {Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis},
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| 772 |
+
number = 1,
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+
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+
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+
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+
volume = 1,
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+
year = 1964
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+
}
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| 779 |
+
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+
@article{compcor,
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+
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+
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+
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+
title = {A component based noise correction method ({CompCor}) for {BOLD} and perfusion based fMRI},
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+
volume = 37,
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+
year = 2007
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+
}
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+
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+
@article{hcppipelines,
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+
author = {Glasser, Matthew F. and Sotiropoulos, Stamatios N. and Wilson, J. Anthony and Coalson, Timothy S. and Fischl, Bruce and Andersson, Jesper L. and Xu, Junqian and Jbabdi, Saad and Webster, Matthew and Polimeni, Jonathan R. and Van Essen, David C. and Jenkinson, Mark},
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+
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| 797 |
+
journal = {NeuroImage},
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| 798 |
+
pages = {105-124},
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| 799 |
+
series = {Mapping the Connectome},
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| 800 |
+
title = {The minimal preprocessing pipelines for the Human Connectome Project},
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| 801 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913005053},
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| 802 |
+
volume = 80,
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+
year = 2013
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+
}
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| 805 |
+
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| 806 |
+
@article{fs_template,
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+
author = {Reuter, Martin and Rosas, Herminia Diana and Fischl, Bruce},
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| 808 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
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+
journal = {NeuroImage},
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+
number = 4,
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+
pages = {1181-1196},
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| 812 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
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| 813 |
+
volume = 53,
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| 814 |
+
year = 2010
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| 815 |
+
}
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| 816 |
+
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| 817 |
+
@article{afni,
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| 818 |
+
author = {Cox, Robert W. and Hyde, James S.},
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+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
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| 820 |
+
journal = {NMR in Biomedicine},
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| 821 |
+
number = {4-5},
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| 822 |
+
pages = {171-178},
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+
title = {Software tools for analysis and visualization of fMRI data},
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| 824 |
+
volume = 10,
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+
year = 1997
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+
}
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| 827 |
+
|
| 828 |
+
@article{posse_t2s,
|
| 829 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
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| 830 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 831 |
+
journal = {Magnetic Resonance in Medicine},
|
| 832 |
+
number = 1,
|
| 833 |
+
pages = {87-97},
|
| 834 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 835 |
+
volume = 42,
|
| 836 |
+
year = 1999
|
| 837 |
+
}
|
| 838 |
+
</pre>
|
| 839 |
+
</div>
|
| 840 |
+
</div>
|
| 841 |
+
</div>
|
| 842 |
+
|
| 843 |
+
<div id="errors">
|
| 844 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 845 |
+
<p>No errors to report!</p>
|
| 846 |
+
</div>
|
| 847 |
+
|
| 848 |
+
|
| 849 |
+
<script type="text/javascript">
|
| 850 |
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function toggle(id) {
|
| 851 |
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var element = document.getElementById(id);
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| 852 |
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if(element.style.display == 'block')
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element.style.display = 'none';
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else
|
| 855 |
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element.style.display = 'block';
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| 856 |
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|
| 857 |
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</script>
|
| 858 |
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</body>
|
| 859 |
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</html>
|
derivatives/fmriprep/sub-S09.html
ADDED
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|
| 1 |
+
<?xml version="1.0" encoding="utf-8" ?>
|
| 2 |
+
<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
|
| 3 |
+
<html xmlns="http://www.w3.org/1999/xhtml" xml:lang="en" lang="en">
|
| 4 |
+
<head>
|
| 5 |
+
<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
|
| 6 |
+
<meta name="generator" content="Docutils 0.12: http://docutils.sourceforge.net/" />
|
| 7 |
+
<title></title>
|
| 8 |
+
<script src="https://code.jquery.com/jquery-3.3.1.slim.min.js" integrity="sha384-q8i/X+965DzO0rT7abK41JStQIAqVgRVzpbzo5smXKp4YfRvH+8abtTE1Pi6jizo" crossorigin="anonymous"></script>
|
| 9 |
+
<script src="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/js/bootstrap.min.js" integrity="sha384-ChfqqxuZUCnJSK3+MXmPNIyE6ZbWh2IMqE241rYiqJxyMiZ6OW/JmZQ5stwEULTy" crossorigin="anonymous"></script>
|
| 10 |
+
<link rel="stylesheet" href="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/css/bootstrap.min.css" integrity="sha384-MCw98/SFnGE8fJT3GXwEOngsV7Zt27NXFoaoApmYm81iuXoPkFOJwJ8ERdknLPMO" crossorigin="anonymous">
|
| 11 |
+
<style type="text/css">
|
| 12 |
+
.sub-report-title {}
|
| 13 |
+
.run-title {}
|
| 14 |
+
|
| 15 |
+
h1 { padding-top: 35px; }
|
| 16 |
+
h2 { padding-top: 20px; }
|
| 17 |
+
h3 { padding-top: 15px; }
|
| 18 |
+
|
| 19 |
+
.elem-desc {}
|
| 20 |
+
.elem-caption {
|
| 21 |
+
margin-top: 15px
|
| 22 |
+
margin-bottom: 0;
|
| 23 |
+
}
|
| 24 |
+
.elem-filename {}
|
| 25 |
+
|
| 26 |
+
div.elem-image {
|
| 27 |
+
width: 100%;
|
| 28 |
+
page-break-before:always;
|
| 29 |
+
}
|
| 30 |
+
|
| 31 |
+
.elem-image object.svg-reportlet {
|
| 32 |
+
width: 100%;
|
| 33 |
+
padding-bottom: 5px;
|
| 34 |
+
}
|
| 35 |
+
body {
|
| 36 |
+
padding: 65px 10px 10px;
|
| 37 |
+
}
|
| 38 |
+
|
| 39 |
+
.boiler-html {
|
| 40 |
+
font-family: "Bitstream Charter", "Georgia", Times;
|
| 41 |
+
margin: 20px 25px;
|
| 42 |
+
padding: 10px;
|
| 43 |
+
background-color: #F8F9FA;
|
| 44 |
+
}
|
| 45 |
+
|
| 46 |
+
div#boilerplate pre {
|
| 47 |
+
margin: 20px 25px;
|
| 48 |
+
padding: 10px;
|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
+
|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S09</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 160x240x256</li>
|
| 105 |
+
<li>Output voxel size: 1.1mm x 1mm x 1mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S09/figures/sub-S09_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S09/figures/sub-S09_dseg.svg" target="_blank">sub-S09/figures/sub-S09_dseg.svg</a>
|
| 115 |
+
</div>
|
| 116 |
+
|
| 117 |
+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S09/figures/sub-S09_space-MNI152NLin2009cAsym_T1w.svg">
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Problem loading figure sub-S09/figures/sub-S09_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
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Get figure file: <a href="./sub-S09/figures/sub-S09_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S09/figures/sub-S09_space-MNI152NLin2009cAsym_T1w.svg</a>
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<div id="Functional">
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<h1 class="sub-report-title">Functional</h1>
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<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
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<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
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<ul class="elem-desc">
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<li>Repetition time (TR): 2.4s</li>
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<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
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<li>Slice timing correction: Not applied</li>
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<li>Susceptibility distortion correction: None</li>
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<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
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<li>Confounds collected: csf, csf_derivative1, csf_derivative1_power2, csf_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_power2, global_signal_derivative1_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, a_comp_cor_84, a_comp_cor_85, a_comp_cor_86, a_comp_cor_87, a_comp_cor_88, a_comp_cor_89, a_comp_cor_90, a_comp_cor_91, a_comp_cor_92, a_comp_cor_93, a_comp_cor_94, a_comp_cor_95, a_comp_cor_96, a_comp_cor_97, a_comp_cor_98, a_comp_cor_99, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_derivative1_power2, trans_x_power2, trans_y, trans_y_derivative1, trans_y_power2, trans_y_derivative1_power2, trans_z, trans_z_derivative1, trans_z_power2, trans_z_derivative1_power2, rot_x, rot_x_derivative1, rot_x_derivative1_power2, rot_x_power2, rot_y, rot_y_derivative1, rot_y_power2, rot_y_derivative1_power2, rot_z, rot_z_derivative1, rot_z_power2, rot_z_derivative1_power2, motion_outlier00</li>
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<li>Non-steady-state volumes: 0</li>
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</ul>
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</div>
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<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
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<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S09/figures/sub-S09_task-localizer_desc-flirtbbr_bold.svg">
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Problem loading figure sub-S09/figures/sub-S09_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
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Get figure file: <a href="./sub-S09/figures/sub-S09_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S09/figures/sub-S09_task-localizer_desc-flirtbbr_bold.svg</a>
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<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
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<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S09/figures/sub-S09_task-localizer_desc-rois_bold.svg" style="width: 100%" />
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<div class="elem-filename">
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Get figure file: <a href="./sub-S09/figures/sub-S09_task-localizer_desc-rois_bold.svg" target="_blank">sub-S09/figures/sub-S09_task-localizer_desc-rois_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
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<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S09/figures/sub-S09_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
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<div class="elem-filename">
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Get figure file: <a href="./sub-S09/figures/sub-S09_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S09/figures/sub-S09_task-localizer_desc-compcorvar_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S09/figures/sub-S09_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S09/figures/sub-S09_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S09/figures/sub-S09_task-localizer_desc-carpetplot_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S09/figures/sub-S09_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S09/figures/sub-S09_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S09/figures/sub-S09_task-localizer_desc-confoundcorr_bold.svg</a>
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</div>
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</div>
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</div>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S09 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-13 18:30:55 -0400</li>
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</ul>
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</div>
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</div>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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| 251 |
+
<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
|
| 252 |
+
</div>
|
| 253 |
+
<div id="ref-nipype2">
|
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+
<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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+
</div>
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+
<div id="ref-bbr">
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+
<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
|
| 258 |
+
</div>
|
| 259 |
+
<div id="ref-mcflirt">
|
| 260 |
+
<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
|
| 261 |
+
</div>
|
| 262 |
+
<div id="ref-flirt">
|
| 263 |
+
<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
|
| 264 |
+
</div>
|
| 265 |
+
<div id="ref-lanczos">
|
| 266 |
+
<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
|
| 267 |
+
</div>
|
| 268 |
+
<div id="ref-power_fd_dvars">
|
| 269 |
+
<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
|
| 270 |
+
</div>
|
| 271 |
+
<div id="ref-confounds_satterthwaite_2013">
|
| 272 |
+
<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
|
| 273 |
+
</div>
|
| 274 |
+
<div id="ref-n4">
|
| 275 |
+
<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
|
| 276 |
+
</div>
|
| 277 |
+
<div id="ref-fsl_fast">
|
| 278 |
+
<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
|
| 279 |
+
</div>
|
| 280 |
+
</div></div></div>
|
| 281 |
+
<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
|
| 282 |
+
Results included in this manuscript come from preprocessing
|
| 283 |
+
performed using *fMRIPrep* 20.0.6
|
| 284 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 285 |
+
which is based on *Nipype* 1.4.2
|
| 286 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 287 |
+
|
| 288 |
+
Anatomical data preprocessing
|
| 289 |
+
|
| 290 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 291 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 292 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 293 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 294 |
+
as target template.
|
| 295 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 296 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 297 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 298 |
+
@fsl_fast].
|
| 299 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 300 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 301 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 302 |
+
The following template was selected for spatial normalization:
|
| 303 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 304 |
+
|
| 305 |
+
Functional data preprocessing
|
| 306 |
+
|
| 307 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 308 |
+
tasks and sessions), the following preprocessing was performed.
|
| 309 |
+
First, a reference volume and its skull-stripped version were generated
|
| 310 |
+
using a custom methodology of *fMRIPrep*.
|
| 311 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 312 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 313 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 314 |
+
cost-function.
|
| 315 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 316 |
+
for distortions remaining in the BOLD reference.
|
| 317 |
+
Head-motion parameters with respect to the BOLD reference
|
| 318 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 319 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 320 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 321 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 322 |
+
were resampled onto their original, native space by applying
|
| 323 |
+
the transforms to correct for head-motion.
|
| 324 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 325 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 326 |
+
The BOLD time-series were resampled into standard space,
|
| 327 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 328 |
+
First, a reference volume and its skull-stripped version were generated
|
| 329 |
+
using a custom methodology of *fMRIPrep*.
|
| 330 |
+
Several confounding time-series were calculated based on the
|
| 331 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 332 |
+
three region-wise global signals.
|
| 333 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 334 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 335 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 336 |
+
the whole-brain masks.
|
| 337 |
+
Additionally, a set of physiological regressors were extracted to
|
| 338 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 339 |
+
Principal components are estimated after high-pass filtering the
|
| 340 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 341 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 342 |
+
and anatomical (aCompCor).
|
| 343 |
+
tCompCor components are then calculated from the top 5% variable
|
| 344 |
+
voxels within a mask covering the subcortical regions.
|
| 345 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 346 |
+
which ensures it does not include cortical GM regions.
|
| 347 |
+
For aCompCor, components are calculated within the intersection of
|
| 348 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 349 |
+
in T1w space, after their projection to the native space of each
|
| 350 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 351 |
+
are also calculated separately within the WM and CSF masks.
|
| 352 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 353 |
+
values are retained, such that the retained components' time series are
|
| 354 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 355 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 356 |
+
consideration.
|
| 357 |
+
The head-motion estimates calculated in the correction step were also
|
| 358 |
+
placed within the corresponding confounds file.
|
| 359 |
+
The confound time series derived from head motion estimates and global
|
| 360 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 361 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 362 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 363 |
+
were annotated as motion outliers.
|
| 364 |
+
All resamplings can be performed with *a single interpolation
|
| 365 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 366 |
+
transform matrices, susceptibility distortion correction when available,
|
| 367 |
+
and co-registrations to anatomical and output spaces).
|
| 368 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 369 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 370 |
+
effects of other kernels [@lanczos].
|
| 371 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 372 |
+
(FreeSurfer).
|
| 373 |
+
|
| 374 |
+
|
| 375 |
+
Many internal operations of *fMRIPrep* use
|
| 376 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 377 |
+
mostly within the functional processing workflow.
|
| 378 |
+
For more details of the pipeline, see [the section corresponding
|
| 379 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 380 |
+
|
| 381 |
+
|
| 382 |
+
### Copyright Waiver
|
| 383 |
+
|
| 384 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 385 |
+
with the express intention that users should copy and paste this
|
| 386 |
+
text into their manuscripts *unchanged*.
|
| 387 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 388 |
+
|
| 389 |
+
### References
|
| 390 |
+
|
| 391 |
+
</pre>
|
| 392 |
+
</div>
|
| 393 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 394 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 395 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 396 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 397 |
+
|
| 398 |
+
\begin{description}
|
| 399 |
+
\item[Anatomical data preprocessing]
|
| 400 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 401 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 402 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 403 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 404 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 405 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 406 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 407 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 408 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 409 |
+
Volume-based spatial normalization to one standard space
|
| 410 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 411 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 412 |
+
of both T1w reference and the T1w template. The following template was
|
| 413 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 414 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 415 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 416 |
+
\item[Functional data preprocessing]
|
| 417 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 418 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 419 |
+
volume and its skull-stripped version were generated using a custom
|
| 420 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 421 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 422 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 423 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 424 |
+
was configured with nine degrees of freedom to account for distortions
|
| 425 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 426 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 427 |
+
rotation and translation parameters) are estimated before any
|
| 428 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 429 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 430 |
+
correction when applied) were resampled onto their original, native
|
| 431 |
+
space by applying the transforms to correct for head-motion. These
|
| 432 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 433 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 434 |
+
time-series were resampled into standard space, generating a
|
| 435 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 436 |
+
reference volume and its skull-stripped version were generated using a
|
| 437 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 438 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 439 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 440 |
+
DVARS are calculated for each functional run, both using their
|
| 441 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 442 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 443 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 444 |
+
physiological regressors were extracted to allow for component-based
|
| 445 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 446 |
+
components are estimated after high-pass filtering the
|
| 447 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 448 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 449 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 450 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 451 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 452 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 453 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 454 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 455 |
+
in T1w space, after their projection to the native space of each
|
| 456 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 457 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 458 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 459 |
+
singular values are retained, such that the retained components' time
|
| 460 |
+
series are sufficient to explain 50 percent of variance across the
|
| 461 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 462 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 463 |
+
the correction step were also placed within the corresponding confounds
|
| 464 |
+
file. The confound time series derived from head motion estimates and
|
| 465 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 466 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 467 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 468 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 469 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 470 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 471 |
+
distortion correction when available, and co-registrations to anatomical
|
| 472 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 473 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 474 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 475 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 476 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 477 |
+
\end{description}
|
| 478 |
+
|
| 479 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 480 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 481 |
+
processing workflow. For more details of the pipeline, see
|
| 482 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 483 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 484 |
+
|
| 485 |
+
\hypertarget{copyright-waiver}{%
|
| 486 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 487 |
+
|
| 488 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 489 |
+
the express intention that users should copy and paste this text into
|
| 490 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 491 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 492 |
+
|
| 493 |
+
\hypertarget{references}{%
|
| 494 |
+
\subsubsection{References}\label{references}}
|
| 495 |
+
|
| 496 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 497 |
+
<h3>Bibliography</h3>
|
| 498 |
+
<pre>@article{fmriprep1,
|
| 499 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
|
| 500 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
|
| 501 |
+
year = {2018},
|
| 502 |
+
doi = {10.1038/s41592-018-0235-4},
|
| 503 |
+
journal = {Nature Methods}
|
| 504 |
+
}
|
| 505 |
+
|
| 506 |
+
@article{fmriprep2,
|
| 507 |
+
author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
|
| 508 |
+
title = {fMRIPrep},
|
| 509 |
+
year = 2018,
|
| 510 |
+
doi = {10.5281/zenodo.852659},
|
| 511 |
+
publisher = {Zenodo},
|
| 512 |
+
journal = {Software}
|
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| 808 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
|
| 809 |
+
journal = {NeuroImage},
|
| 810 |
+
number = 4,
|
| 811 |
+
pages = {1181-1196},
|
| 812 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
|
| 813 |
+
volume = 53,
|
| 814 |
+
year = 2010
|
| 815 |
+
}
|
| 816 |
+
|
| 817 |
+
@article{afni,
|
| 818 |
+
author = {Cox, Robert W. and Hyde, James S.},
|
| 819 |
+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
|
| 820 |
+
journal = {NMR in Biomedicine},
|
| 821 |
+
number = {4-5},
|
| 822 |
+
pages = {171-178},
|
| 823 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 824 |
+
volume = 10,
|
| 825 |
+
year = 1997
|
| 826 |
+
}
|
| 827 |
+
|
| 828 |
+
@article{posse_t2s,
|
| 829 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 830 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 831 |
+
journal = {Magnetic Resonance in Medicine},
|
| 832 |
+
number = 1,
|
| 833 |
+
pages = {87-97},
|
| 834 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 835 |
+
volume = 42,
|
| 836 |
+
year = 1999
|
| 837 |
+
}
|
| 838 |
+
</pre>
|
| 839 |
+
</div>
|
| 840 |
+
</div>
|
| 841 |
+
</div>
|
| 842 |
+
|
| 843 |
+
<div id="errors">
|
| 844 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 845 |
+
<p>No errors to report!</p>
|
| 846 |
+
</div>
|
| 847 |
+
|
| 848 |
+
|
| 849 |
+
<script type="text/javascript">
|
| 850 |
+
function toggle(id) {
|
| 851 |
+
var element = document.getElementById(id);
|
| 852 |
+
if(element.style.display == 'block')
|
| 853 |
+
element.style.display = 'none';
|
| 854 |
+
else
|
| 855 |
+
element.style.display = 'block';
|
| 856 |
+
}
|
| 857 |
+
</script>
|
| 858 |
+
</body>
|
| 859 |
+
</html>
|
derivatives/fmriprep/sub-S10.html
ADDED
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div#boilerplate pre {
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margin: 20px 25px;
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background-color: #F8F9FA;
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}
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+
#errors div, #errors p {
|
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+
padding-left: 1em;
|
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}
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+
</style>
|
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+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S10</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 192x256x128</li>
|
| 105 |
+
<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S10/figures/sub-S10_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S10/figures/sub-S10_dseg.svg" target="_blank">sub-S10/figures/sub-S10_dseg.svg</a>
|
| 115 |
+
</div>
|
| 116 |
+
|
| 117 |
+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S10/figures/sub-S10_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S10/figures/sub-S10_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S10/figures/sub-S10_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S10/figures/sub-S10_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_derivative1_power2, csf_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_power2, global_signal_derivative1_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, a_comp_cor_84, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_derivative1_power2, trans_x_power2, trans_y, trans_y_derivative1, trans_y_power2, trans_y_derivative1_power2, trans_z, trans_z_derivative1, trans_z_power2, trans_z_derivative1_power2, rot_x, rot_x_derivative1, rot_x_derivative1_power2, rot_x_power2, rot_y, rot_y_derivative1, rot_y_derivative1_power2, rot_y_power2, rot_z, rot_z_derivative1, rot_z_derivative1_power2, rot_z_power2, motion_outlier00, motion_outlier01, motion_outlier02</li>
|
| 139 |
+
<li>Non-steady-state volumes: 0</li>
|
| 140 |
+
</ul>
|
| 141 |
+
</div>
|
| 142 |
+
<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
|
| 143 |
+
<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
|
| 144 |
+
<p class="elem-desc">
|
| 145 |
+
The qform has been copied from sform.
|
| 146 |
+
The difference in angle is 0.
|
| 147 |
+
The difference in translation is 0.
|
| 148 |
+
</p>
|
| 149 |
+
</div>
|
| 150 |
+
<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
|
| 151 |
+
<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S10/figures/sub-S10_task-localizer_desc-flirtbbr_bold.svg">
|
| 152 |
+
Problem loading figure sub-S10/figures/sub-S10_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 153 |
+
</div>
|
| 154 |
+
<div class="elem-filename">
|
| 155 |
+
Get figure file: <a href="./sub-S10/figures/sub-S10_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S10/figures/sub-S10_task-localizer_desc-flirtbbr_bold.svg</a>
|
| 156 |
+
</div>
|
| 157 |
+
|
| 158 |
+
</div>
|
| 159 |
+
<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
|
| 160 |
+
<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S10/figures/sub-S10_task-localizer_desc-rois_bold.svg" style="width: 100%" />
|
| 161 |
+
</div>
|
| 162 |
+
<div class="elem-filename">
|
| 163 |
+
Get figure file: <a href="./sub-S10/figures/sub-S10_task-localizer_desc-rois_bold.svg" target="_blank">sub-S10/figures/sub-S10_task-localizer_desc-rois_bold.svg</a>
|
| 164 |
+
</div>
|
| 165 |
+
|
| 166 |
+
</div>
|
| 167 |
+
<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
|
| 168 |
+
<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S10/figures/sub-S10_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
|
| 169 |
+
</div>
|
| 170 |
+
<div class="elem-filename">
|
| 171 |
+
Get figure file: <a href="./sub-S10/figures/sub-S10_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S10/figures/sub-S10_task-localizer_desc-compcorvar_bold.svg</a>
|
| 172 |
+
</div>
|
| 173 |
+
|
| 174 |
+
</div>
|
| 175 |
+
<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
|
| 176 |
+
<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S10/figures/sub-S10_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
|
| 177 |
+
</div>
|
| 178 |
+
<div class="elem-filename">
|
| 179 |
+
Get figure file: <a href="./sub-S10/figures/sub-S10_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S10/figures/sub-S10_task-localizer_desc-carpetplot_bold.svg</a>
|
| 180 |
+
</div>
|
| 181 |
+
|
| 182 |
+
</div>
|
| 183 |
+
<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
|
| 184 |
+
<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
|
| 185 |
+
(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
|
| 186 |
+
Right: magnitude of the correlation between each confound time series and the
|
| 187 |
+
mean global signal. Strong correlations might be indicative of partial volume
|
| 188 |
+
effects and can inform decisions about feature orthogonalization prior to
|
| 189 |
+
confound regression.
|
| 190 |
+
</p> <img class="svg-reportlet" src="./sub-S10/figures/sub-S10_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
|
| 191 |
+
</div>
|
| 192 |
+
<div class="elem-filename">
|
| 193 |
+
Get figure file: <a href="./sub-S10/figures/sub-S10_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S10/figures/sub-S10_task-localizer_desc-confoundcorr_bold.svg</a>
|
| 194 |
+
</div>
|
| 195 |
+
|
| 196 |
+
</div>
|
| 197 |
+
</div>
|
| 198 |
+
<div id="About">
|
| 199 |
+
<h1 class="sub-report-title">About</h1>
|
| 200 |
+
<div id="datatype-anat_desc-about_suffix-T1w">
|
| 201 |
+
<ul>
|
| 202 |
+
<li>fMRIPrep version: 20.0.6</li>
|
| 203 |
+
<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S10 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-13 11:39:43 -0400</li>
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</ul>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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+
<dt>Functional data preprocessing</dt>
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+
<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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</div>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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</div>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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</div>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
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<div id="ref-lanczos">
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<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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</div>
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<div id="ref-power_fd_dvars">
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<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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</div>
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<div id="ref-confounds_satterthwaite_2013">
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<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
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</div>
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<div id="ref-n4">
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<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
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</div>
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<div id="ref-fsl_fast">
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<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
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</div>
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</div></div></div>
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<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
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+
Results included in this manuscript come from preprocessing
|
| 291 |
+
performed using *fMRIPrep* 20.0.6
|
| 292 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 293 |
+
which is based on *Nipype* 1.4.2
|
| 294 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
|
| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
|
| 506 |
+
<pre>@article{fmriprep1,
|
| 507 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
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| 508 |
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+
}
|
| 657 |
+
|
| 658 |
+
@phdthesis{fieldmapless2,
|
| 659 |
+
address = {Berlin},
|
| 660 |
+
author = {Huntenburg, Julia M.},
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| 661 |
+
language = {eng},
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| 662 |
+
school = {Freie Universität},
|
| 663 |
+
title = {Evaluating nonlinear coregistration of {BOLD} {EPI} and T1w images},
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| 664 |
+
type = {Master's Thesis},
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+
url = {http://hdl.handle.net/11858/00-001M-0000-002B-1CB5-A},
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| 666 |
+
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}
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| 671 |
+
doi = {10.1371/journal.pone.0152472},
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| 672 |
+
issn = {1932-6203},
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| 673 |
+
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| 674 |
+
number = 3,
|
| 675 |
+
pages = {e0152472},
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| 676 |
+
title = {Characterization and Correction of Geometric Distortions in 814 Diffusion Weighted Images},
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+
url = {http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152472},
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+
volume = 11,
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+
year = 2016
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}
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+
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+
@article{flirt,
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| 683 |
+
title = {A global optimisation method for robust affine registration of brain images},
|
| 684 |
+
volume = {5},
|
| 685 |
+
issn = {1361-8415},
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+
url = {http://www.sciencedirect.com/science/article/pii/S1361841501000366},
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| 687 |
+
doi = {10.1016/S1361-8415(01)00036-6},
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+
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| 689 |
+
urldate = {2018-07-27},
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+
journal = {Medical Image Analysis},
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| 691 |
+
author = {Jenkinson, Mark and Smith, Stephen},
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| 692 |
+
year = {2001},
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| 693 |
+
keywords = {Affine transformation, flirt, fsl, Global optimisation, Multi-resolution search, Multimodal registration, Robustness},
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| 694 |
+
pages = {143--156}
|
| 695 |
+
}
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| 696 |
+
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| 697 |
+
@article{mcflirt,
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| 698 |
+
author = {Jenkinson, Mark and Bannister, Peter and Brady, Michael and Smith, Stephen},
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| 699 |
+
doi = {10.1006/nimg.2002.1132},
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| 700 |
+
issn = {1053-8119},
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| 701 |
+
journal = {NeuroImage},
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| 702 |
+
number = 2,
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| 703 |
+
pages = {825-841},
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| 704 |
+
title = {Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images},
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| 705 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811902911328},
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| 706 |
+
volume = 17,
|
| 707 |
+
year = 2002
|
| 708 |
+
}
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| 709 |
+
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| 710 |
+
@article{bbr,
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| 711 |
+
author = {Greve, Douglas N and Fischl, Bruce},
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| 712 |
+
doi = {10.1016/j.neuroimage.2009.06.060},
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| 713 |
+
issn = {1095-9572},
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| 714 |
+
journal = {NeuroImage},
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| 715 |
+
number = 1,
|
| 716 |
+
pages = {63-72},
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| 717 |
+
title = {Accurate and robust brain image alignment using boundary-based registration},
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| 718 |
+
volume = 48,
|
| 719 |
+
year = 2009
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| 720 |
+
}
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| 721 |
+
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| 722 |
+
@article{aroma,
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| 723 |
+
author = {Pruim, Raimon H. R. and Mennes, Maarten and van Rooij, Daan and Llera, Alberto and Buitelaar, Jan K. and Beckmann, Christian F.},
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| 724 |
+
doi = {10.1016/j.neuroimage.2015.02.064},
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| 725 |
+
issn = {1053-8119},
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| 726 |
+
journal = {NeuroImage},
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| 727 |
+
number = {Supplement C},
|
| 728 |
+
pages = {267-277},
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| 729 |
+
shorttitle = {ICA-AROMA},
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| 730 |
+
title = {ICA-{AROMA}: A robust {ICA}-based strategy for removing motion artifacts from fMRI data},
|
| 731 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811915001822},
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| 732 |
+
volume = 112,
|
| 733 |
+
year = 2015
|
| 734 |
+
}
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| 735 |
+
|
| 736 |
+
@article{power_fd_dvars,
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| 737 |
+
author = {Power, Jonathan D. and Mitra, Anish and Laumann, Timothy O. and Snyder, Abraham Z. and Schlaggar, Bradley L. and Petersen, Steven E.},
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| 738 |
+
doi = {10.1016/j.neuroimage.2013.08.048},
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| 739 |
+
issn = {1053-8119},
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| 740 |
+
journal = {NeuroImage},
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| 741 |
+
number = {Supplement C},
|
| 742 |
+
pages = {320-341},
|
| 743 |
+
title = {Methods to detect, characterize, and remove motion artifact in resting state fMRI},
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| 744 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913009117},
|
| 745 |
+
volume = 84,
|
| 746 |
+
year = 2014
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| 747 |
+
}
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| 748 |
+
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| 749 |
+
@article{confounds_satterthwaite_2013,
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| 750 |
+
author = {Satterthwaite, Theodore D. and Elliott, Mark A. and Gerraty, Raphael T. and Ruparel, Kosha and Loughead, James and Calkins, Monica E. and Eickhoff, Simon B. and Hakonarson, Hakon and Gur, Ruben C. and Gur, Raquel E. and Wolf, Daniel H.},
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| 751 |
+
doi = {10.1016/j.neuroimage.2012.08.052},
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| 752 |
+
issn = {10538119},
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| 753 |
+
journal = {NeuroImage},
|
| 754 |
+
number = 1,
|
| 755 |
+
pages = {240--256},
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| 756 |
+
title = {{An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data}},
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| 757 |
+
url = {http://linkinghub.elsevier.com/retrieve/pii/S1053811912008609},
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| 758 |
+
volume = 64,
|
| 759 |
+
year = 2013
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| 760 |
+
}
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| 761 |
+
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| 762 |
+
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| 763 |
+
@article{nilearn,
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| 764 |
+
author = {Abraham, Alexandre and Pedregosa, Fabian and Eickenberg, Michael and Gervais, Philippe and Mueller, Andreas and Kossaifi, Jean and Gramfort, Alexandre and Thirion, Bertrand and Varoquaux, Gael},
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| 765 |
+
doi = {10.3389/fninf.2014.00014},
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| 766 |
+
issn = {1662-5196},
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| 767 |
+
journal = {Frontiers in Neuroinformatics},
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| 768 |
+
language = {English},
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| 769 |
+
title = {Machine learning for neuroimaging with scikit-learn},
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| 770 |
+
url = {https://www.frontiersin.org/articles/10.3389/fninf.2014.00014/full},
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| 771 |
+
volume = 8,
|
| 772 |
+
year = 2014
|
| 773 |
+
}
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| 774 |
+
|
| 775 |
+
@article{lanczos,
|
| 776 |
+
author = {Lanczos, C.},
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| 777 |
+
doi = {10.1137/0701007},
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| 778 |
+
issn = {0887-459X},
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| 779 |
+
journal = {Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis},
|
| 780 |
+
number = 1,
|
| 781 |
+
pages = {76-85},
|
| 782 |
+
title = {Evaluation of Noisy Data},
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| 783 |
+
url = {http://epubs.siam.org/doi/10.1137/0701007},
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| 784 |
+
volume = 1,
|
| 785 |
+
year = 1964
|
| 786 |
+
}
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| 787 |
+
|
| 788 |
+
@article{compcor,
|
| 789 |
+
author = {Behzadi, Yashar and Restom, Khaled and Liau, Joy and Liu, Thomas T.},
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| 790 |
+
doi = {10.1016/j.neuroimage.2007.04.042},
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| 791 |
+
issn = {1053-8119},
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| 792 |
+
journal = {NeuroImage},
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| 793 |
+
number = 1,
|
| 794 |
+
pages = {90-101},
|
| 795 |
+
title = {A component based noise correction method ({CompCor}) for {BOLD} and perfusion based fMRI},
|
| 796 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811907003837},
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| 797 |
+
volume = 37,
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| 798 |
+
year = 2007
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| 799 |
+
}
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| 800 |
+
|
| 801 |
+
@article{hcppipelines,
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| 802 |
+
author = {Glasser, Matthew F. and Sotiropoulos, Stamatios N. and Wilson, J. Anthony and Coalson, Timothy S. and Fischl, Bruce and Andersson, Jesper L. and Xu, Junqian and Jbabdi, Saad and Webster, Matthew and Polimeni, Jonathan R. and Van Essen, David C. and Jenkinson, Mark},
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| 803 |
+
doi = {10.1016/j.neuroimage.2013.04.127},
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| 804 |
+
issn = {1053-8119},
|
| 805 |
+
journal = {NeuroImage},
|
| 806 |
+
pages = {105-124},
|
| 807 |
+
series = {Mapping the Connectome},
|
| 808 |
+
title = {The minimal preprocessing pipelines for the Human Connectome Project},
|
| 809 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913005053},
|
| 810 |
+
volume = 80,
|
| 811 |
+
year = 2013
|
| 812 |
+
}
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| 813 |
+
|
| 814 |
+
@article{fs_template,
|
| 815 |
+
author = {Reuter, Martin and Rosas, Herminia Diana and Fischl, Bruce},
|
| 816 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
|
| 817 |
+
journal = {NeuroImage},
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| 818 |
+
number = 4,
|
| 819 |
+
pages = {1181-1196},
|
| 820 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
|
| 821 |
+
volume = 53,
|
| 822 |
+
year = 2010
|
| 823 |
+
}
|
| 824 |
+
|
| 825 |
+
@article{afni,
|
| 826 |
+
author = {Cox, Robert W. and Hyde, James S.},
|
| 827 |
+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
|
| 828 |
+
journal = {NMR in Biomedicine},
|
| 829 |
+
number = {4-5},
|
| 830 |
+
pages = {171-178},
|
| 831 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 832 |
+
volume = 10,
|
| 833 |
+
year = 1997
|
| 834 |
+
}
|
| 835 |
+
|
| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
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function toggle(id) {
|
| 859 |
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var element = document.getElementById(id);
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| 860 |
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if(element.style.display == 'block')
|
| 861 |
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element.style.display = 'none';
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| 862 |
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else
|
| 863 |
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element.style.display = 'block';
|
| 864 |
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}
|
| 865 |
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</script>
|
| 866 |
+
</body>
|
| 867 |
+
</html>
|
derivatives/fmriprep/sub-S11.html
ADDED
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| 1 |
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| 4 |
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| 5 |
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| 6 |
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<title></title>
|
| 8 |
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<style type="text/css">
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.sub-report-title {}
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.run-title {}
|
| 14 |
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|
| 15 |
+
h1 { padding-top: 35px; }
|
| 16 |
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h2 { padding-top: 20px; }
|
| 17 |
+
h3 { padding-top: 15px; }
|
| 18 |
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|
| 19 |
+
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|
| 20 |
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.elem-caption {
|
| 21 |
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margin-top: 15px
|
| 22 |
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margin-bottom: 0;
|
| 23 |
+
}
|
| 24 |
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|
| 25 |
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|
| 26 |
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div.elem-image {
|
| 27 |
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|
| 28 |
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page-break-before:always;
|
| 29 |
+
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|
| 30 |
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|
| 31 |
+
.elem-image object.svg-reportlet {
|
| 32 |
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width: 100%;
|
| 33 |
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| 34 |
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|
| 35 |
+
body {
|
| 36 |
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padding: 65px 10px 10px;
|
| 37 |
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|
| 38 |
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|
| 39 |
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|
| 40 |
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| 41 |
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| 42 |
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|
| 43 |
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|
| 44 |
+
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|
| 45 |
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|
| 46 |
+
div#boilerplate pre {
|
| 47 |
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margin: 20px 25px;
|
| 48 |
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padding: 10px;
|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
+
|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S11</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 192x256x128</li>
|
| 105 |
+
<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S11/figures/sub-S11_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S11/figures/sub-S11_dseg.svg" target="_blank">sub-S11/figures/sub-S11_dseg.svg</a>
|
| 115 |
+
</div>
|
| 116 |
+
|
| 117 |
+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S11/figures/sub-S11_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S11/figures/sub-S11_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
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Get figure file: <a href="./sub-S11/figures/sub-S11_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S11/figures/sub-S11_space-MNI152NLin2009cAsym_T1w.svg</a>
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<div id="Functional">
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<h1 class="sub-report-title">Functional</h1>
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<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
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<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
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<ul class="elem-desc">
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<li>Repetition time (TR): 2.4s</li>
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<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
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<li>Slice timing correction: Not applied</li>
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<li>Susceptibility distortion correction: None</li>
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<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
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<li>Confounds collected: csf, csf_derivative1, csf_power2, csf_derivative1_power2, white_matter, white_matter_derivative1, white_matter_power2, white_matter_derivative1_power2, global_signal, global_signal_derivative1, global_signal_power2, global_signal_derivative1_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_power2, trans_x_derivative1_power2, trans_y, trans_y_derivative1, trans_y_derivative1_power2, trans_y_power2, trans_z, trans_z_derivative1, trans_z_derivative1_power2, trans_z_power2, rot_x, rot_x_derivative1, rot_x_power2, rot_x_derivative1_power2, rot_y, rot_y_derivative1, rot_y_derivative1_power2, rot_y_power2, rot_z, rot_z_derivative1, rot_z_power2, rot_z_derivative1_power2, motion_outlier00, motion_outlier01, motion_outlier02, motion_outlier03, motion_outlier04, motion_outlier05, motion_outlier06, motion_outlier07, motion_outlier08</li>
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<li>Non-steady-state volumes: 0</li>
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</ul>
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</div>
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<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
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<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
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<p class="elem-desc">
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The qform has been copied from sform.
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The difference in angle is 0.
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The difference in translation is 0.
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</p>
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</div>
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<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
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<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S11/figures/sub-S11_task-localizer_desc-flirtbbr_bold.svg">
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Problem loading figure sub-S11/figures/sub-S11_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S11/figures/sub-S11_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S11/figures/sub-S11_task-localizer_desc-flirtbbr_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
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<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S11/figures/sub-S11_task-localizer_desc-rois_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S11/figures/sub-S11_task-localizer_desc-rois_bold.svg" target="_blank">sub-S11/figures/sub-S11_task-localizer_desc-rois_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
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<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S11/figures/sub-S11_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S11/figures/sub-S11_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S11/figures/sub-S11_task-localizer_desc-compcorvar_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S11/figures/sub-S11_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S11/figures/sub-S11_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S11/figures/sub-S11_task-localizer_desc-carpetplot_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S11/figures/sub-S11_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S11/figures/sub-S11_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S11/figures/sub-S11_task-localizer_desc-confoundcorr_bold.svg</a>
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</div>
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</div>
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</div>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
|
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S11 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-11 15:31:55 -0400</li>
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</ul>
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</div>
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</div>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
|
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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</li>
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</ul>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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</div>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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</div>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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+
<div id="ref-mcflirt">
|
| 268 |
+
<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
|
| 269 |
+
</div>
|
| 270 |
+
<div id="ref-flirt">
|
| 271 |
+
<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
|
| 272 |
+
</div>
|
| 273 |
+
<div id="ref-lanczos">
|
| 274 |
+
<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
|
| 275 |
+
</div>
|
| 276 |
+
<div id="ref-power_fd_dvars">
|
| 277 |
+
<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
|
| 278 |
+
</div>
|
| 279 |
+
<div id="ref-confounds_satterthwaite_2013">
|
| 280 |
+
<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
|
| 281 |
+
</div>
|
| 282 |
+
<div id="ref-n4">
|
| 283 |
+
<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
|
| 284 |
+
</div>
|
| 285 |
+
<div id="ref-fsl_fast">
|
| 286 |
+
<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
|
| 287 |
+
</div>
|
| 288 |
+
</div></div></div>
|
| 289 |
+
<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
|
| 290 |
+
Results included in this manuscript come from preprocessing
|
| 291 |
+
performed using *fMRIPrep* 20.0.6
|
| 292 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 293 |
+
which is based on *Nipype* 1.4.2
|
| 294 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
|
| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
|
| 506 |
+
<pre>@article{fmriprep1,
|
| 507 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
|
| 508 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
|
| 509 |
+
year = {2018},
|
| 510 |
+
doi = {10.1038/s41592-018-0235-4},
|
| 511 |
+
journal = {Nature Methods}
|
| 512 |
+
}
|
| 513 |
+
|
| 514 |
+
@article{fmriprep2,
|
| 515 |
+
author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
|
| 516 |
+
title = {fMRIPrep},
|
| 517 |
+
year = 2018,
|
| 518 |
+
doi = {10.5281/zenodo.852659},
|
| 519 |
+
publisher = {Zenodo},
|
| 520 |
+
journal = {Software}
|
| 521 |
+
}
|
| 522 |
+
|
| 523 |
+
@article{nipype1,
|
| 524 |
+
author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
|
| 525 |
+
doi = {10.3389/fninf.2011.00013},
|
| 526 |
+
journal = {Frontiers in Neuroinformatics},
|
| 527 |
+
pages = 13,
|
| 528 |
+
shorttitle = {Nipype},
|
| 529 |
+
title = {Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in Python},
|
| 530 |
+
volume = 5,
|
| 531 |
+
year = 2011
|
| 532 |
+
}
|
| 533 |
+
|
| 534 |
+
@article{nipype2,
|
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journal = {NMR in Biomedicine},
|
| 829 |
+
number = {4-5},
|
| 830 |
+
pages = {171-178},
|
| 831 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 832 |
+
volume = 10,
|
| 833 |
+
year = 1997
|
| 834 |
+
}
|
| 835 |
+
|
| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
+
function toggle(id) {
|
| 859 |
+
var element = document.getElementById(id);
|
| 860 |
+
if(element.style.display == 'block')
|
| 861 |
+
element.style.display = 'none';
|
| 862 |
+
else
|
| 863 |
+
element.style.display = 'block';
|
| 864 |
+
}
|
| 865 |
+
</script>
|
| 866 |
+
</body>
|
| 867 |
+
</html>
|
derivatives/fmriprep/sub-S12.html
ADDED
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@@ -0,0 +1,867 @@
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}
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</style>
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<body>
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<div class="collapse navbar-collapse">
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| 62 |
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<ul class="navbar-nav">
|
| 63 |
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<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
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| 66 |
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<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
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<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
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<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
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</div>
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</li>
|
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<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
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<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
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<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
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</ul>
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</div>
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</nav>
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<noscript>
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<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
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</noscript>
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<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
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| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
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<ul class="elem-desc">
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| 85 |
+
<li>Subject ID: S12</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
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<ul class="elem-desc">
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| 89 |
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<li>Task: localizer (1 run)</li>
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+
</ul>
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+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
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</ul>
|
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+
</div>
|
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+
</div>
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<div id="Anatomical">
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<h1 class="sub-report-title">Anatomical</h1>
|
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<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
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<h3 class="elem-title">Anatomical Conformation</h3>
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<ul class="elem-desc">
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<li>Input T1w images: 1</li>
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<li>Output orientation: RAS</li>
|
| 104 |
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<li>Output dimensions: 192x256x128</li>
|
| 105 |
+
<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
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| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
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+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S12/figures/sub-S12_dseg.svg" style="width: 100%" />
|
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+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S12/figures/sub-S12_dseg.svg" target="_blank">sub-S12/figures/sub-S12_dseg.svg</a>
|
| 115 |
+
</div>
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+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
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| 119 |
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<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S12/figures/sub-S12_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S12/figures/sub-S12_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S12/figures/sub-S12_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S12/figures/sub-S12_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_derivative1_power2, csf_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, cosine00, cosine01, cosine02, non_steady_state_outlier00, non_steady_state_outlier01, non_steady_state_outlier02, trans_x, trans_x_derivative1, trans_x_power2, trans_x_derivative1_power2, trans_y, trans_y_derivative1, trans_y_power2, trans_y_derivative1_power2, trans_z, trans_z_derivative1, trans_z_derivative1_power2, trans_z_power2, rot_x, rot_x_derivative1, rot_x_derivative1_power2, rot_x_power2, rot_y, rot_y_derivative1, rot_y_power2, rot_y_derivative1_power2, rot_z, rot_z_derivative1, rot_z_derivative1_power2, rot_z_power2, motion_outlier00, motion_outlier01, motion_outlier02, motion_outlier03, motion_outlier04, motion_outlier05, motion_outlier06, motion_outlier07, motion_outlier08, motion_outlier09, motion_outlier10, motion_outlier11, motion_outlier12, motion_outlier13, motion_outlier14, motion_outlier15, motion_outlier16, motion_outlier17, motion_outlier18, motion_outlier19, motion_outlier20, motion_outlier21, motion_outlier22, motion_outlier23</li>
|
| 139 |
+
<li>Non-steady-state volumes: 3</li>
|
| 140 |
+
</ul>
|
| 141 |
+
</div>
|
| 142 |
+
<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
|
| 143 |
+
<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
|
| 144 |
+
<p class="elem-desc">
|
| 145 |
+
The qform has been copied from sform.
|
| 146 |
+
The difference in angle is 0.
|
| 147 |
+
The difference in translation is 0.
|
| 148 |
+
</p>
|
| 149 |
+
</div>
|
| 150 |
+
<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
|
| 151 |
+
<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S12/figures/sub-S12_task-localizer_desc-flirtbbr_bold.svg">
|
| 152 |
+
Problem loading figure sub-S12/figures/sub-S12_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 153 |
+
</div>
|
| 154 |
+
<div class="elem-filename">
|
| 155 |
+
Get figure file: <a href="./sub-S12/figures/sub-S12_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S12/figures/sub-S12_task-localizer_desc-flirtbbr_bold.svg</a>
|
| 156 |
+
</div>
|
| 157 |
+
|
| 158 |
+
</div>
|
| 159 |
+
<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
|
| 160 |
+
<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S12/figures/sub-S12_task-localizer_desc-rois_bold.svg" style="width: 100%" />
|
| 161 |
+
</div>
|
| 162 |
+
<div class="elem-filename">
|
| 163 |
+
Get figure file: <a href="./sub-S12/figures/sub-S12_task-localizer_desc-rois_bold.svg" target="_blank">sub-S12/figures/sub-S12_task-localizer_desc-rois_bold.svg</a>
|
| 164 |
+
</div>
|
| 165 |
+
|
| 166 |
+
</div>
|
| 167 |
+
<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
|
| 168 |
+
<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S12/figures/sub-S12_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
|
| 169 |
+
</div>
|
| 170 |
+
<div class="elem-filename">
|
| 171 |
+
Get figure file: <a href="./sub-S12/figures/sub-S12_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S12/figures/sub-S12_task-localizer_desc-compcorvar_bold.svg</a>
|
| 172 |
+
</div>
|
| 173 |
+
|
| 174 |
+
</div>
|
| 175 |
+
<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
|
| 176 |
+
<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S12/figures/sub-S12_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
|
| 177 |
+
</div>
|
| 178 |
+
<div class="elem-filename">
|
| 179 |
+
Get figure file: <a href="./sub-S12/figures/sub-S12_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S12/figures/sub-S12_task-localizer_desc-carpetplot_bold.svg</a>
|
| 180 |
+
</div>
|
| 181 |
+
|
| 182 |
+
</div>
|
| 183 |
+
<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
|
| 184 |
+
<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
|
| 185 |
+
(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
|
| 186 |
+
Right: magnitude of the correlation between each confound time series and the
|
| 187 |
+
mean global signal. Strong correlations might be indicative of partial volume
|
| 188 |
+
effects and can inform decisions about feature orthogonalization prior to
|
| 189 |
+
confound regression.
|
| 190 |
+
</p> <img class="svg-reportlet" src="./sub-S12/figures/sub-S12_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
|
| 191 |
+
</div>
|
| 192 |
+
<div class="elem-filename">
|
| 193 |
+
Get figure file: <a href="./sub-S12/figures/sub-S12_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S12/figures/sub-S12_task-localizer_desc-confoundcorr_bold.svg</a>
|
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+
</div>
|
| 195 |
+
|
| 196 |
+
</div>
|
| 197 |
+
</div>
|
| 198 |
+
<div id="About">
|
| 199 |
+
<h1 class="sub-report-title">About</h1>
|
| 200 |
+
<div id="datatype-anat_desc-about_suffix-T1w">
|
| 201 |
+
<ul>
|
| 202 |
+
<li>fMRIPrep version: 20.0.6</li>
|
| 203 |
+
<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S12 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
|
| 204 |
+
<li>Date preprocessed: 2020-05-11 16:57:42 -0400</li>
|
| 205 |
+
</ul>
|
| 206 |
+
</div>
|
| 207 |
+
</div>
|
| 208 |
+
</div>
|
| 209 |
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|
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<div id="boilerplate">
|
| 211 |
+
<h1 class="sub-report-title">Methods</h1>
|
| 212 |
+
<p>We kindly ask to report results preprocessed with this tool using the following
|
| 213 |
+
boilerplate.</p>
|
| 214 |
+
<ul class="nav nav-tabs" id="myTab" role="tablist">
|
| 215 |
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<li class="nav-item">
|
| 216 |
+
<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
|
| 217 |
+
</li>
|
| 218 |
+
<li class="nav-item">
|
| 219 |
+
<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
|
| 220 |
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</li>
|
| 221 |
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<li class="nav-item">
|
| 222 |
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
|
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</li>
|
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</ul>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
|
| 227 |
+
<dl>
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+
<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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+
</dd>
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+
<dt>Functional data preprocessing</dt>
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+
<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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+
</dd>
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+
</dl>
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+
<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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+
<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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+
<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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</div>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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</div>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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+
<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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+
<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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</div>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
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<div id="ref-lanczos">
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<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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</div>
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<div id="ref-power_fd_dvars">
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<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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</div>
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<div id="ref-confounds_satterthwaite_2013">
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<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
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</div>
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<div id="ref-n4">
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<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
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</div>
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<div id="ref-fsl_fast">
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<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
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</div>
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</div></div></div>
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<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
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Results included in this manuscript come from preprocessing
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| 291 |
+
performed using *fMRIPrep* 20.0.6
|
| 292 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 293 |
+
which is based on *Nipype* 1.4.2
|
| 294 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
|
| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
|
| 506 |
+
<pre>@article{fmriprep1,
|
| 507 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
|
| 508 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
|
| 509 |
+
year = {2018},
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| 510 |
+
doi = {10.1038/s41592-018-0235-4},
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| 511 |
+
journal = {Nature Methods}
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| 512 |
+
}
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+
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@article{fmriprep2,
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| 515 |
+
author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
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| 516 |
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title = {fMRIPrep},
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| 517 |
+
year = 2018,
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| 518 |
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doi = {10.5281/zenodo.852659},
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publisher = {Zenodo},
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journal = {Software}
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}
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@article{nipype1,
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+
author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
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+
journal = {Frontiers in Neuroinformatics},
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pages = 13,
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shorttitle = {Nipype},
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title = {Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in Python},
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+
title = {Nipype},
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+
year = 2018,
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| 538 |
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doi = {10.5281/zenodo.596855},
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+
publisher = {Zenodo},
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journal = {Software}
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+
}
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+
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+
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doi = {10.1109/TMI.2010.2046908},
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journal = {IEEE Transactions on Medical Imaging},
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number = 6,
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pages = {1310-1320},
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title = {N4ITK: Improved N3 Bias Correction},
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volume = 29,
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}
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pages = {e1005350},
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title = {Mindboggling morphometry of human brains},
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url = {http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005350},
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}
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+
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+
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+
author = {Mazziotta, John C. and Toga, Arthur W. and Evans, Alan and Fox, Peter and Lancaster, Jack},
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| 588 |
+
volume = {2},
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| 589 |
+
issn = {1053-8119},
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+
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+
title = {Unbiased nonlinear average age-appropriate brain templates from birth to adulthood},
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author = {Fonov, VS and Evans, AC and McKinstry, RC and Almli, CR and Collins, DL},
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|
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address = {Berlin},
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school = {Freie Universität},
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year = 2014
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@article{flirt,
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title = {A global optimisation method for robust affine registration of brain images},
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url = {http://www.sciencedirect.com/science/article/pii/S1361841501000366},
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| 687 |
+
doi = {10.1016/S1361-8415(01)00036-6},
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| 688 |
+
number = {2},
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| 689 |
+
urldate = {2018-07-27},
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| 690 |
+
journal = {Medical Image Analysis},
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| 691 |
+
author = {Jenkinson, Mark and Smith, Stephen},
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| 692 |
+
year = {2001},
|
| 693 |
+
keywords = {Affine transformation, flirt, fsl, Global optimisation, Multi-resolution search, Multimodal registration, Robustness},
|
| 694 |
+
pages = {143--156}
|
| 695 |
+
}
|
| 696 |
+
|
| 697 |
+
@article{mcflirt,
|
| 698 |
+
author = {Jenkinson, Mark and Bannister, Peter and Brady, Michael and Smith, Stephen},
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| 699 |
+
doi = {10.1006/nimg.2002.1132},
|
| 700 |
+
issn = {1053-8119},
|
| 701 |
+
journal = {NeuroImage},
|
| 702 |
+
number = 2,
|
| 703 |
+
pages = {825-841},
|
| 704 |
+
title = {Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images},
|
| 705 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811902911328},
|
| 706 |
+
volume = 17,
|
| 707 |
+
year = 2002
|
| 708 |
+
}
|
| 709 |
+
|
| 710 |
+
@article{bbr,
|
| 711 |
+
author = {Greve, Douglas N and Fischl, Bruce},
|
| 712 |
+
doi = {10.1016/j.neuroimage.2009.06.060},
|
| 713 |
+
issn = {1095-9572},
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| 714 |
+
journal = {NeuroImage},
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| 715 |
+
number = 1,
|
| 716 |
+
pages = {63-72},
|
| 717 |
+
title = {Accurate and robust brain image alignment using boundary-based registration},
|
| 718 |
+
volume = 48,
|
| 719 |
+
year = 2009
|
| 720 |
+
}
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| 721 |
+
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| 722 |
+
@article{aroma,
|
| 723 |
+
author = {Pruim, Raimon H. R. and Mennes, Maarten and van Rooij, Daan and Llera, Alberto and Buitelaar, Jan K. and Beckmann, Christian F.},
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| 724 |
+
doi = {10.1016/j.neuroimage.2015.02.064},
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| 725 |
+
issn = {1053-8119},
|
| 726 |
+
journal = {NeuroImage},
|
| 727 |
+
number = {Supplement C},
|
| 728 |
+
pages = {267-277},
|
| 729 |
+
shorttitle = {ICA-AROMA},
|
| 730 |
+
title = {ICA-{AROMA}: A robust {ICA}-based strategy for removing motion artifacts from fMRI data},
|
| 731 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811915001822},
|
| 732 |
+
volume = 112,
|
| 733 |
+
year = 2015
|
| 734 |
+
}
|
| 735 |
+
|
| 736 |
+
@article{power_fd_dvars,
|
| 737 |
+
author = {Power, Jonathan D. and Mitra, Anish and Laumann, Timothy O. and Snyder, Abraham Z. and Schlaggar, Bradley L. and Petersen, Steven E.},
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| 738 |
+
doi = {10.1016/j.neuroimage.2013.08.048},
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| 739 |
+
issn = {1053-8119},
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| 740 |
+
journal = {NeuroImage},
|
| 741 |
+
number = {Supplement C},
|
| 742 |
+
pages = {320-341},
|
| 743 |
+
title = {Methods to detect, characterize, and remove motion artifact in resting state fMRI},
|
| 744 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913009117},
|
| 745 |
+
volume = 84,
|
| 746 |
+
year = 2014
|
| 747 |
+
}
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| 748 |
+
|
| 749 |
+
@article{confounds_satterthwaite_2013,
|
| 750 |
+
author = {Satterthwaite, Theodore D. and Elliott, Mark A. and Gerraty, Raphael T. and Ruparel, Kosha and Loughead, James and Calkins, Monica E. and Eickhoff, Simon B. and Hakonarson, Hakon and Gur, Ruben C. and Gur, Raquel E. and Wolf, Daniel H.},
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| 751 |
+
doi = {10.1016/j.neuroimage.2012.08.052},
|
| 752 |
+
issn = {10538119},
|
| 753 |
+
journal = {NeuroImage},
|
| 754 |
+
number = 1,
|
| 755 |
+
pages = {240--256},
|
| 756 |
+
title = {{An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data}},
|
| 757 |
+
url = {http://linkinghub.elsevier.com/retrieve/pii/S1053811912008609},
|
| 758 |
+
volume = 64,
|
| 759 |
+
year = 2013
|
| 760 |
+
}
|
| 761 |
+
|
| 762 |
+
|
| 763 |
+
@article{nilearn,
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| 764 |
+
author = {Abraham, Alexandre and Pedregosa, Fabian and Eickenberg, Michael and Gervais, Philippe and Mueller, Andreas and Kossaifi, Jean and Gramfort, Alexandre and Thirion, Bertrand and Varoquaux, Gael},
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| 765 |
+
doi = {10.3389/fninf.2014.00014},
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| 766 |
+
issn = {1662-5196},
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| 767 |
+
journal = {Frontiers in Neuroinformatics},
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| 768 |
+
language = {English},
|
| 769 |
+
title = {Machine learning for neuroimaging with scikit-learn},
|
| 770 |
+
url = {https://www.frontiersin.org/articles/10.3389/fninf.2014.00014/full},
|
| 771 |
+
volume = 8,
|
| 772 |
+
year = 2014
|
| 773 |
+
}
|
| 774 |
+
|
| 775 |
+
@article{lanczos,
|
| 776 |
+
author = {Lanczos, C.},
|
| 777 |
+
doi = {10.1137/0701007},
|
| 778 |
+
issn = {0887-459X},
|
| 779 |
+
journal = {Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis},
|
| 780 |
+
number = 1,
|
| 781 |
+
pages = {76-85},
|
| 782 |
+
title = {Evaluation of Noisy Data},
|
| 783 |
+
url = {http://epubs.siam.org/doi/10.1137/0701007},
|
| 784 |
+
volume = 1,
|
| 785 |
+
year = 1964
|
| 786 |
+
}
|
| 787 |
+
|
| 788 |
+
@article{compcor,
|
| 789 |
+
author = {Behzadi, Yashar and Restom, Khaled and Liau, Joy and Liu, Thomas T.},
|
| 790 |
+
doi = {10.1016/j.neuroimage.2007.04.042},
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| 791 |
+
issn = {1053-8119},
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| 792 |
+
journal = {NeuroImage},
|
| 793 |
+
number = 1,
|
| 794 |
+
pages = {90-101},
|
| 795 |
+
title = {A component based noise correction method ({CompCor}) for {BOLD} and perfusion based fMRI},
|
| 796 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811907003837},
|
| 797 |
+
volume = 37,
|
| 798 |
+
year = 2007
|
| 799 |
+
}
|
| 800 |
+
|
| 801 |
+
@article{hcppipelines,
|
| 802 |
+
author = {Glasser, Matthew F. and Sotiropoulos, Stamatios N. and Wilson, J. Anthony and Coalson, Timothy S. and Fischl, Bruce and Andersson, Jesper L. and Xu, Junqian and Jbabdi, Saad and Webster, Matthew and Polimeni, Jonathan R. and Van Essen, David C. and Jenkinson, Mark},
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| 803 |
+
doi = {10.1016/j.neuroimage.2013.04.127},
|
| 804 |
+
issn = {1053-8119},
|
| 805 |
+
journal = {NeuroImage},
|
| 806 |
+
pages = {105-124},
|
| 807 |
+
series = {Mapping the Connectome},
|
| 808 |
+
title = {The minimal preprocessing pipelines for the Human Connectome Project},
|
| 809 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913005053},
|
| 810 |
+
volume = 80,
|
| 811 |
+
year = 2013
|
| 812 |
+
}
|
| 813 |
+
|
| 814 |
+
@article{fs_template,
|
| 815 |
+
author = {Reuter, Martin and Rosas, Herminia Diana and Fischl, Bruce},
|
| 816 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
|
| 817 |
+
journal = {NeuroImage},
|
| 818 |
+
number = 4,
|
| 819 |
+
pages = {1181-1196},
|
| 820 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
|
| 821 |
+
volume = 53,
|
| 822 |
+
year = 2010
|
| 823 |
+
}
|
| 824 |
+
|
| 825 |
+
@article{afni,
|
| 826 |
+
author = {Cox, Robert W. and Hyde, James S.},
|
| 827 |
+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
|
| 828 |
+
journal = {NMR in Biomedicine},
|
| 829 |
+
number = {4-5},
|
| 830 |
+
pages = {171-178},
|
| 831 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 832 |
+
volume = 10,
|
| 833 |
+
year = 1997
|
| 834 |
+
}
|
| 835 |
+
|
| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
+
function toggle(id) {
|
| 859 |
+
var element = document.getElementById(id);
|
| 860 |
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if(element.style.display == 'block')
|
| 861 |
+
element.style.display = 'none';
|
| 862 |
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else
|
| 863 |
+
element.style.display = 'block';
|
| 864 |
+
}
|
| 865 |
+
</script>
|
| 866 |
+
</body>
|
| 867 |
+
</html>
|
derivatives/fmriprep/sub-S13.html
ADDED
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<style type="text/css">
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|
| 15 |
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h1 { padding-top: 35px; }
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| 16 |
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| 17 |
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| 18 |
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|
| 19 |
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| 20 |
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|
| 21 |
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| 23 |
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|
| 24 |
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|
| 25 |
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|
| 26 |
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div.elem-image {
|
| 27 |
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|
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| 32 |
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body {
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| 36 |
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padding: 65px 10px 10px;
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| 37 |
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|
| 38 |
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|
| 39 |
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|
| 40 |
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font-family: "Bitstream Charter", "Georgia", Times;
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| 41 |
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|
| 43 |
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background-color: #F8F9FA;
|
| 44 |
+
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|
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|
| 46 |
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div#boilerplate pre {
|
| 47 |
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margin: 20px 25px;
|
| 48 |
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|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
+
|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S13</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 160x240x256</li>
|
| 105 |
+
<li>Output voxel size: 1.1mm x 1mm x 1mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S13/figures/sub-S13_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S13/figures/sub-S13_dseg.svg" target="_blank">sub-S13/figures/sub-S13_dseg.svg</a>
|
| 115 |
+
</div>
|
| 116 |
+
|
| 117 |
+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S13/figures/sub-S13_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S13/figures/sub-S13_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S13/figures/sub-S13_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S13/figures/sub-S13_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_power2, csf_derivative1_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, t_comp_cor_04, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, a_comp_cor_84, a_comp_cor_85, a_comp_cor_86, a_comp_cor_87, a_comp_cor_88, a_comp_cor_89, a_comp_cor_90, a_comp_cor_91, a_comp_cor_92, a_comp_cor_93, a_comp_cor_94, a_comp_cor_95, a_comp_cor_96, a_comp_cor_97, a_comp_cor_98, a_comp_cor_99, a_comp_cor_100, cosine00, cosine01, cosine02, non_steady_state_outlier00, trans_x, trans_x_derivative1, trans_x_derivative1_power2, trans_x_power2, trans_y, trans_y_derivative1, trans_y_derivative1_power2, trans_y_power2, trans_z, trans_z_derivative1, trans_z_power2, trans_z_derivative1_power2, rot_x, rot_x_derivative1, rot_x_power2, rot_x_derivative1_power2, rot_y, rot_y_derivative1, rot_y_power2, rot_y_derivative1_power2, rot_z, rot_z_derivative1, rot_z_power2, rot_z_derivative1_power2, motion_outlier00, motion_outlier01</li>
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<li>Non-steady-state volumes: 1</li>
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<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S13/figures/sub-S13_task-localizer_desc-flirtbbr_bold.svg">
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Problem loading figure sub-S13/figures/sub-S13_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
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Get figure file: <a href="./sub-S13/figures/sub-S13_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S13/figures/sub-S13_task-localizer_desc-flirtbbr_bold.svg</a>
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<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S13/figures/sub-S13_task-localizer_desc-rois_bold.svg" style="width: 100%" />
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Get figure file: <a href="./sub-S13/figures/sub-S13_task-localizer_desc-rois_bold.svg" target="_blank">sub-S13/figures/sub-S13_task-localizer_desc-rois_bold.svg</a>
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<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S13/figures/sub-S13_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
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Get figure file: <a href="./sub-S13/figures/sub-S13_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S13/figures/sub-S13_task-localizer_desc-compcorvar_bold.svg</a>
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<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S13/figures/sub-S13_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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Get figure file: <a href="./sub-S13/figures/sub-S13_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S13/figures/sub-S13_task-localizer_desc-carpetplot_bold.svg</a>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S13/figures/sub-S13_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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<div class="elem-filename">
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Get figure file: <a href="./sub-S13/figures/sub-S13_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S13/figures/sub-S13_task-localizer_desc-confoundcorr_bold.svg</a>
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</div>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S13 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-12 13:47:46 -0400</li>
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</ul>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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<div id="ref-flirt">
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| 263 |
+
<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
|
| 264 |
+
</div>
|
| 265 |
+
<div id="ref-lanczos">
|
| 266 |
+
<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
|
| 267 |
+
</div>
|
| 268 |
+
<div id="ref-power_fd_dvars">
|
| 269 |
+
<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
|
| 270 |
+
</div>
|
| 271 |
+
<div id="ref-confounds_satterthwaite_2013">
|
| 272 |
+
<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
|
| 273 |
+
</div>
|
| 274 |
+
<div id="ref-n4">
|
| 275 |
+
<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
|
| 276 |
+
</div>
|
| 277 |
+
<div id="ref-fsl_fast">
|
| 278 |
+
<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
|
| 279 |
+
</div>
|
| 280 |
+
</div></div></div>
|
| 281 |
+
<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
|
| 282 |
+
Results included in this manuscript come from preprocessing
|
| 283 |
+
performed using *fMRIPrep* 20.0.6
|
| 284 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 285 |
+
which is based on *Nipype* 1.4.2
|
| 286 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 287 |
+
|
| 288 |
+
Anatomical data preprocessing
|
| 289 |
+
|
| 290 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 291 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 292 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 293 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 294 |
+
as target template.
|
| 295 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 296 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 297 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 298 |
+
@fsl_fast].
|
| 299 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 300 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 301 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 302 |
+
The following template was selected for spatial normalization:
|
| 303 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 304 |
+
|
| 305 |
+
Functional data preprocessing
|
| 306 |
+
|
| 307 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 308 |
+
tasks and sessions), the following preprocessing was performed.
|
| 309 |
+
First, a reference volume and its skull-stripped version were generated
|
| 310 |
+
using a custom methodology of *fMRIPrep*.
|
| 311 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 312 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 313 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 314 |
+
cost-function.
|
| 315 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 316 |
+
for distortions remaining in the BOLD reference.
|
| 317 |
+
Head-motion parameters with respect to the BOLD reference
|
| 318 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 319 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 320 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 321 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 322 |
+
were resampled onto their original, native space by applying
|
| 323 |
+
the transforms to correct for head-motion.
|
| 324 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 325 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 326 |
+
The BOLD time-series were resampled into standard space,
|
| 327 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 328 |
+
First, a reference volume and its skull-stripped version were generated
|
| 329 |
+
using a custom methodology of *fMRIPrep*.
|
| 330 |
+
Several confounding time-series were calculated based on the
|
| 331 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 332 |
+
three region-wise global signals.
|
| 333 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 334 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 335 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 336 |
+
the whole-brain masks.
|
| 337 |
+
Additionally, a set of physiological regressors were extracted to
|
| 338 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 339 |
+
Principal components are estimated after high-pass filtering the
|
| 340 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 341 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 342 |
+
and anatomical (aCompCor).
|
| 343 |
+
tCompCor components are then calculated from the top 5% variable
|
| 344 |
+
voxels within a mask covering the subcortical regions.
|
| 345 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 346 |
+
which ensures it does not include cortical GM regions.
|
| 347 |
+
For aCompCor, components are calculated within the intersection of
|
| 348 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 349 |
+
in T1w space, after their projection to the native space of each
|
| 350 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 351 |
+
are also calculated separately within the WM and CSF masks.
|
| 352 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 353 |
+
values are retained, such that the retained components' time series are
|
| 354 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 355 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 356 |
+
consideration.
|
| 357 |
+
The head-motion estimates calculated in the correction step were also
|
| 358 |
+
placed within the corresponding confounds file.
|
| 359 |
+
The confound time series derived from head motion estimates and global
|
| 360 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 361 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 362 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 363 |
+
were annotated as motion outliers.
|
| 364 |
+
All resamplings can be performed with *a single interpolation
|
| 365 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 366 |
+
transform matrices, susceptibility distortion correction when available,
|
| 367 |
+
and co-registrations to anatomical and output spaces).
|
| 368 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 369 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 370 |
+
effects of other kernels [@lanczos].
|
| 371 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 372 |
+
(FreeSurfer).
|
| 373 |
+
|
| 374 |
+
|
| 375 |
+
Many internal operations of *fMRIPrep* use
|
| 376 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 377 |
+
mostly within the functional processing workflow.
|
| 378 |
+
For more details of the pipeline, see [the section corresponding
|
| 379 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 380 |
+
|
| 381 |
+
|
| 382 |
+
### Copyright Waiver
|
| 383 |
+
|
| 384 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 385 |
+
with the express intention that users should copy and paste this
|
| 386 |
+
text into their manuscripts *unchanged*.
|
| 387 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 388 |
+
|
| 389 |
+
### References
|
| 390 |
+
|
| 391 |
+
</pre>
|
| 392 |
+
</div>
|
| 393 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 394 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 395 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 396 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 397 |
+
|
| 398 |
+
\begin{description}
|
| 399 |
+
\item[Anatomical data preprocessing]
|
| 400 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 401 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 402 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 403 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 404 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 405 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 406 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 407 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 408 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 409 |
+
Volume-based spatial normalization to one standard space
|
| 410 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 411 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 412 |
+
of both T1w reference and the T1w template. The following template was
|
| 413 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 414 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 415 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 416 |
+
\item[Functional data preprocessing]
|
| 417 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 418 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 419 |
+
volume and its skull-stripped version were generated using a custom
|
| 420 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 421 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 422 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 423 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 424 |
+
was configured with nine degrees of freedom to account for distortions
|
| 425 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 426 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 427 |
+
rotation and translation parameters) are estimated before any
|
| 428 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 429 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 430 |
+
correction when applied) were resampled onto their original, native
|
| 431 |
+
space by applying the transforms to correct for head-motion. These
|
| 432 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 433 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 434 |
+
time-series were resampled into standard space, generating a
|
| 435 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 436 |
+
reference volume and its skull-stripped version were generated using a
|
| 437 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 438 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 439 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 440 |
+
DVARS are calculated for each functional run, both using their
|
| 441 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 442 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 443 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 444 |
+
physiological regressors were extracted to allow for component-based
|
| 445 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 446 |
+
components are estimated after high-pass filtering the
|
| 447 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 448 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 449 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 450 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 451 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 452 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 453 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 454 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 455 |
+
in T1w space, after their projection to the native space of each
|
| 456 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 457 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 458 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 459 |
+
singular values are retained, such that the retained components' time
|
| 460 |
+
series are sufficient to explain 50 percent of variance across the
|
| 461 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 462 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 463 |
+
the correction step were also placed within the corresponding confounds
|
| 464 |
+
file. The confound time series derived from head motion estimates and
|
| 465 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 466 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 467 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 468 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 469 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 470 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 471 |
+
distortion correction when available, and co-registrations to anatomical
|
| 472 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 473 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 474 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 475 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 476 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 477 |
+
\end{description}
|
| 478 |
+
|
| 479 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 480 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 481 |
+
processing workflow. For more details of the pipeline, see
|
| 482 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 483 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 484 |
+
|
| 485 |
+
\hypertarget{copyright-waiver}{%
|
| 486 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 487 |
+
|
| 488 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 489 |
+
the express intention that users should copy and paste this text into
|
| 490 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 491 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 492 |
+
|
| 493 |
+
\hypertarget{references}{%
|
| 494 |
+
\subsubsection{References}\label{references}}
|
| 495 |
+
|
| 496 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 497 |
+
<h3>Bibliography</h3>
|
| 498 |
+
<pre>@article{fmriprep1,
|
| 499 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
|
| 500 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
|
| 501 |
+
year = {2018},
|
| 502 |
+
doi = {10.1038/s41592-018-0235-4},
|
| 503 |
+
journal = {Nature Methods}
|
| 504 |
+
}
|
| 505 |
+
|
| 506 |
+
@article{fmriprep2,
|
| 507 |
+
author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
|
| 508 |
+
title = {fMRIPrep},
|
| 509 |
+
year = 2018,
|
| 510 |
+
doi = {10.5281/zenodo.852659},
|
| 511 |
+
publisher = {Zenodo},
|
| 512 |
+
journal = {Software}
|
| 513 |
+
}
|
| 514 |
+
|
| 515 |
+
@article{nipype1,
|
| 516 |
+
author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
|
| 517 |
+
doi = {10.3389/fninf.2011.00013},
|
| 518 |
+
journal = {Frontiers in Neuroinformatics},
|
| 519 |
+
pages = 13,
|
| 520 |
+
shorttitle = {Nipype},
|
| 521 |
+
title = {Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in Python},
|
| 522 |
+
volume = 5,
|
| 523 |
+
year = 2011
|
| 524 |
+
}
|
| 525 |
+
|
| 526 |
+
@article{nipype2,
|
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| 821 |
+
number = {4-5},
|
| 822 |
+
pages = {171-178},
|
| 823 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 824 |
+
volume = 10,
|
| 825 |
+
year = 1997
|
| 826 |
+
}
|
| 827 |
+
|
| 828 |
+
@article{posse_t2s,
|
| 829 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 830 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 831 |
+
journal = {Magnetic Resonance in Medicine},
|
| 832 |
+
number = 1,
|
| 833 |
+
pages = {87-97},
|
| 834 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 835 |
+
volume = 42,
|
| 836 |
+
year = 1999
|
| 837 |
+
}
|
| 838 |
+
</pre>
|
| 839 |
+
</div>
|
| 840 |
+
</div>
|
| 841 |
+
</div>
|
| 842 |
+
|
| 843 |
+
<div id="errors">
|
| 844 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 845 |
+
<p>No errors to report!</p>
|
| 846 |
+
</div>
|
| 847 |
+
|
| 848 |
+
|
| 849 |
+
<script type="text/javascript">
|
| 850 |
+
function toggle(id) {
|
| 851 |
+
var element = document.getElementById(id);
|
| 852 |
+
if(element.style.display == 'block')
|
| 853 |
+
element.style.display = 'none';
|
| 854 |
+
else
|
| 855 |
+
element.style.display = 'block';
|
| 856 |
+
}
|
| 857 |
+
</script>
|
| 858 |
+
</body>
|
| 859 |
+
</html>
|
derivatives/fmriprep/sub-S14.html
ADDED
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padding-left: 1em;
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}
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</style>
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<body>
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<div class="collapse navbar-collapse">
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| 62 |
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<ul class="navbar-nav">
|
| 63 |
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<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
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<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
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| 66 |
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<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
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<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
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<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
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</div>
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</li>
|
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<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
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<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
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<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
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</ul>
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</div>
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</nav>
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<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
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</noscript>
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<div id="Summary">
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| 82 |
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<h1 class="sub-report-title">Summary</h1>
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| 83 |
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<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
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<ul class="elem-desc">
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<li>Subject ID: S14</li>
|
| 86 |
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<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
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+
<ul class="elem-desc">
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| 89 |
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<li>Task: localizer (1 run)</li>
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</ul>
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<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
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+
</ul>
|
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+
</div>
|
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+
</div>
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<div id="Anatomical">
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<h1 class="sub-report-title">Anatomical</h1>
|
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<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
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<h3 class="elem-title">Anatomical Conformation</h3>
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<ul class="elem-desc">
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<li>Input T1w images: 1</li>
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<li>Output orientation: RAS</li>
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<li>Output dimensions: 192x256x128</li>
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<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
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| 110 |
+
<div id="datatype-anat_suffix-dseg">
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+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S14/figures/sub-S14_dseg.svg" style="width: 100%" />
|
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+
</div>
|
| 113 |
+
<div class="elem-filename">
|
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+
Get figure file: <a href="./sub-S14/figures/sub-S14_dseg.svg" target="_blank">sub-S14/figures/sub-S14_dseg.svg</a>
|
| 115 |
+
</div>
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</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
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<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S14/figures/sub-S14_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S14/figures/sub-S14_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S14/figures/sub-S14_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S14/figures/sub-S14_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
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<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_power2, csf_derivative1_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_power2, global_signal_derivative1_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, t_comp_cor_04, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_power2, trans_x_derivative1_power2, trans_y, trans_y_derivative1, trans_y_derivative1_power2, trans_y_power2, trans_z, trans_z_derivative1, trans_z_derivative1_power2, trans_z_power2, rot_x, rot_x_derivative1, rot_x_derivative1_power2, rot_x_power2, rot_y, rot_y_derivative1, rot_y_derivative1_power2, rot_y_power2, rot_z, rot_z_derivative1, rot_z_power2, rot_z_derivative1_power2, motion_outlier00, motion_outlier01, motion_outlier02, motion_outlier03, motion_outlier04, motion_outlier05, motion_outlier06, motion_outlier07, motion_outlier08, motion_outlier09, motion_outlier10, motion_outlier11, motion_outlier12, motion_outlier13, motion_outlier14, motion_outlier15, motion_outlier16, motion_outlier17, motion_outlier18, motion_outlier19</li>
|
| 139 |
+
<li>Non-steady-state volumes: 0</li>
|
| 140 |
+
</ul>
|
| 141 |
+
</div>
|
| 142 |
+
<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
|
| 143 |
+
<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
|
| 144 |
+
<p class="elem-desc">
|
| 145 |
+
The qform has been copied from sform.
|
| 146 |
+
The difference in angle is 0.
|
| 147 |
+
The difference in translation is 0.
|
| 148 |
+
</p>
|
| 149 |
+
</div>
|
| 150 |
+
<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
|
| 151 |
+
<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S14/figures/sub-S14_task-localizer_desc-flirtbbr_bold.svg">
|
| 152 |
+
Problem loading figure sub-S14/figures/sub-S14_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 153 |
+
</div>
|
| 154 |
+
<div class="elem-filename">
|
| 155 |
+
Get figure file: <a href="./sub-S14/figures/sub-S14_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S14/figures/sub-S14_task-localizer_desc-flirtbbr_bold.svg</a>
|
| 156 |
+
</div>
|
| 157 |
+
|
| 158 |
+
</div>
|
| 159 |
+
<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
|
| 160 |
+
<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S14/figures/sub-S14_task-localizer_desc-rois_bold.svg" style="width: 100%" />
|
| 161 |
+
</div>
|
| 162 |
+
<div class="elem-filename">
|
| 163 |
+
Get figure file: <a href="./sub-S14/figures/sub-S14_task-localizer_desc-rois_bold.svg" target="_blank">sub-S14/figures/sub-S14_task-localizer_desc-rois_bold.svg</a>
|
| 164 |
+
</div>
|
| 165 |
+
|
| 166 |
+
</div>
|
| 167 |
+
<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
|
| 168 |
+
<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S14/figures/sub-S14_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
|
| 169 |
+
</div>
|
| 170 |
+
<div class="elem-filename">
|
| 171 |
+
Get figure file: <a href="./sub-S14/figures/sub-S14_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S14/figures/sub-S14_task-localizer_desc-compcorvar_bold.svg</a>
|
| 172 |
+
</div>
|
| 173 |
+
|
| 174 |
+
</div>
|
| 175 |
+
<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
|
| 176 |
+
<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S14/figures/sub-S14_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
|
| 177 |
+
</div>
|
| 178 |
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<div class="elem-filename">
|
| 179 |
+
Get figure file: <a href="./sub-S14/figures/sub-S14_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S14/figures/sub-S14_task-localizer_desc-carpetplot_bold.svg</a>
|
| 180 |
+
</div>
|
| 181 |
+
|
| 182 |
+
</div>
|
| 183 |
+
<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
|
| 184 |
+
<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
|
| 185 |
+
(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
|
| 186 |
+
Right: magnitude of the correlation between each confound time series and the
|
| 187 |
+
mean global signal. Strong correlations might be indicative of partial volume
|
| 188 |
+
effects and can inform decisions about feature orthogonalization prior to
|
| 189 |
+
confound regression.
|
| 190 |
+
</p> <img class="svg-reportlet" src="./sub-S14/figures/sub-S14_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
|
| 191 |
+
</div>
|
| 192 |
+
<div class="elem-filename">
|
| 193 |
+
Get figure file: <a href="./sub-S14/figures/sub-S14_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S14/figures/sub-S14_task-localizer_desc-confoundcorr_bold.svg</a>
|
| 194 |
+
</div>
|
| 195 |
+
|
| 196 |
+
</div>
|
| 197 |
+
</div>
|
| 198 |
+
<div id="About">
|
| 199 |
+
<h1 class="sub-report-title">About</h1>
|
| 200 |
+
<div id="datatype-anat_desc-about_suffix-T1w">
|
| 201 |
+
<ul>
|
| 202 |
+
<li>fMRIPrep version: 20.0.6</li>
|
| 203 |
+
<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S14 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
|
| 204 |
+
<li>Date preprocessed: 2020-05-12 13:47:45 -0400</li>
|
| 205 |
+
</ul>
|
| 206 |
+
</div>
|
| 207 |
+
</div>
|
| 208 |
+
</div>
|
| 209 |
+
|
| 210 |
+
<div id="boilerplate">
|
| 211 |
+
<h1 class="sub-report-title">Methods</h1>
|
| 212 |
+
<p>We kindly ask to report results preprocessed with this tool using the following
|
| 213 |
+
boilerplate.</p>
|
| 214 |
+
<ul class="nav nav-tabs" id="myTab" role="tablist">
|
| 215 |
+
<li class="nav-item">
|
| 216 |
+
<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
|
| 217 |
+
</li>
|
| 218 |
+
<li class="nav-item">
|
| 219 |
+
<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
|
| 220 |
+
</li>
|
| 221 |
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<li class="nav-item">
|
| 222 |
+
<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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</li>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
|
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+
<dl>
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+
<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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+
</dd>
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+
<dt>Functional data preprocessing</dt>
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+
<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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+
</dd>
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+
</dl>
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+
<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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+
<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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</div>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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</div>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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+
<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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+
<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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</div>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
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<div id="ref-lanczos">
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<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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</div>
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<div id="ref-power_fd_dvars">
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<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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</div>
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<div id="ref-confounds_satterthwaite_2013">
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<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
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</div>
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<div id="ref-n4">
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<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
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</div>
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<div id="ref-fsl_fast">
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<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
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</div>
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</div></div></div>
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<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
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+
Results included in this manuscript come from preprocessing
|
| 291 |
+
performed using *fMRIPrep* 20.0.6
|
| 292 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 293 |
+
which is based on *Nipype* 1.4.2
|
| 294 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
|
| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
|
| 506 |
+
<pre>@article{fmriprep1,
|
| 507 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
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| 508 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
|
| 509 |
+
year = {2018},
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| 510 |
+
doi = {10.1038/s41592-018-0235-4},
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| 511 |
+
journal = {Nature Methods}
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| 512 |
+
}
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+
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@article{fmriprep2,
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| 515 |
+
author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
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| 516 |
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title = {fMRIPrep},
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| 517 |
+
year = 2018,
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| 518 |
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publisher = {Zenodo},
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}
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author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
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+
journal = {Frontiers in Neuroinformatics},
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pages = 13,
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shorttitle = {Nipype},
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title = {Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in Python},
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+
title = {Nipype},
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year = 2018,
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| 538 |
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doi = {10.5281/zenodo.596855},
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+
publisher = {Zenodo},
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journal = {Software}
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}
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+
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+
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doi = {10.1109/TMI.2010.2046908},
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journal = {IEEE Transactions on Medical Imaging},
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number = 6,
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pages = {1310-1320},
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title = {N4ITK: Improved N3 Bias Correction},
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}
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pages = {e1005350},
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title = {Mindboggling morphometry of human brains},
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url = {http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005350},
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}
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+
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+
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+
author = {Mazziotta, John C. and Toga, Arthur W. and Evans, Alan and Fox, Peter and Lancaster, Jack},
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| 588 |
+
volume = {2},
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| 589 |
+
issn = {1053-8119},
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+
title = {Unbiased nonlinear average age-appropriate brain templates from birth to adulthood},
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author = {Fonov, VS and Evans, AC and McKinstry, RC and Almli, CR and Collins, DL},
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|
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address = {Berlin},
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school = {Freie Universität},
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year = 2014
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@article{flirt,
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title = {A global optimisation method for robust affine registration of brain images},
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volume = {5},
|
| 685 |
+
issn = {1361-8415},
|
| 686 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1361841501000366},
|
| 687 |
+
doi = {10.1016/S1361-8415(01)00036-6},
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| 688 |
+
number = {2},
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| 689 |
+
urldate = {2018-07-27},
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| 690 |
+
journal = {Medical Image Analysis},
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| 691 |
+
author = {Jenkinson, Mark and Smith, Stephen},
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| 692 |
+
year = {2001},
|
| 693 |
+
keywords = {Affine transformation, flirt, fsl, Global optimisation, Multi-resolution search, Multimodal registration, Robustness},
|
| 694 |
+
pages = {143--156}
|
| 695 |
+
}
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| 696 |
+
|
| 697 |
+
@article{mcflirt,
|
| 698 |
+
author = {Jenkinson, Mark and Bannister, Peter and Brady, Michael and Smith, Stephen},
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| 699 |
+
doi = {10.1006/nimg.2002.1132},
|
| 700 |
+
issn = {1053-8119},
|
| 701 |
+
journal = {NeuroImage},
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| 702 |
+
number = 2,
|
| 703 |
+
pages = {825-841},
|
| 704 |
+
title = {Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images},
|
| 705 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811902911328},
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| 706 |
+
volume = 17,
|
| 707 |
+
year = 2002
|
| 708 |
+
}
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| 709 |
+
|
| 710 |
+
@article{bbr,
|
| 711 |
+
author = {Greve, Douglas N and Fischl, Bruce},
|
| 712 |
+
doi = {10.1016/j.neuroimage.2009.06.060},
|
| 713 |
+
issn = {1095-9572},
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| 714 |
+
journal = {NeuroImage},
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| 715 |
+
number = 1,
|
| 716 |
+
pages = {63-72},
|
| 717 |
+
title = {Accurate and robust brain image alignment using boundary-based registration},
|
| 718 |
+
volume = 48,
|
| 719 |
+
year = 2009
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| 720 |
+
}
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| 721 |
+
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| 722 |
+
@article{aroma,
|
| 723 |
+
author = {Pruim, Raimon H. R. and Mennes, Maarten and van Rooij, Daan and Llera, Alberto and Buitelaar, Jan K. and Beckmann, Christian F.},
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| 724 |
+
doi = {10.1016/j.neuroimage.2015.02.064},
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| 725 |
+
issn = {1053-8119},
|
| 726 |
+
journal = {NeuroImage},
|
| 727 |
+
number = {Supplement C},
|
| 728 |
+
pages = {267-277},
|
| 729 |
+
shorttitle = {ICA-AROMA},
|
| 730 |
+
title = {ICA-{AROMA}: A robust {ICA}-based strategy for removing motion artifacts from fMRI data},
|
| 731 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811915001822},
|
| 732 |
+
volume = 112,
|
| 733 |
+
year = 2015
|
| 734 |
+
}
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| 735 |
+
|
| 736 |
+
@article{power_fd_dvars,
|
| 737 |
+
author = {Power, Jonathan D. and Mitra, Anish and Laumann, Timothy O. and Snyder, Abraham Z. and Schlaggar, Bradley L. and Petersen, Steven E.},
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| 738 |
+
doi = {10.1016/j.neuroimage.2013.08.048},
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| 739 |
+
issn = {1053-8119},
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| 740 |
+
journal = {NeuroImage},
|
| 741 |
+
number = {Supplement C},
|
| 742 |
+
pages = {320-341},
|
| 743 |
+
title = {Methods to detect, characterize, and remove motion artifact in resting state fMRI},
|
| 744 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913009117},
|
| 745 |
+
volume = 84,
|
| 746 |
+
year = 2014
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| 747 |
+
}
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| 748 |
+
|
| 749 |
+
@article{confounds_satterthwaite_2013,
|
| 750 |
+
author = {Satterthwaite, Theodore D. and Elliott, Mark A. and Gerraty, Raphael T. and Ruparel, Kosha and Loughead, James and Calkins, Monica E. and Eickhoff, Simon B. and Hakonarson, Hakon and Gur, Ruben C. and Gur, Raquel E. and Wolf, Daniel H.},
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| 751 |
+
doi = {10.1016/j.neuroimage.2012.08.052},
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| 752 |
+
issn = {10538119},
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| 753 |
+
journal = {NeuroImage},
|
| 754 |
+
number = 1,
|
| 755 |
+
pages = {240--256},
|
| 756 |
+
title = {{An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data}},
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| 757 |
+
url = {http://linkinghub.elsevier.com/retrieve/pii/S1053811912008609},
|
| 758 |
+
volume = 64,
|
| 759 |
+
year = 2013
|
| 760 |
+
}
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| 761 |
+
|
| 762 |
+
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| 763 |
+
@article{nilearn,
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| 764 |
+
author = {Abraham, Alexandre and Pedregosa, Fabian and Eickenberg, Michael and Gervais, Philippe and Mueller, Andreas and Kossaifi, Jean and Gramfort, Alexandre and Thirion, Bertrand and Varoquaux, Gael},
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| 765 |
+
doi = {10.3389/fninf.2014.00014},
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| 766 |
+
issn = {1662-5196},
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| 767 |
+
journal = {Frontiers in Neuroinformatics},
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| 768 |
+
language = {English},
|
| 769 |
+
title = {Machine learning for neuroimaging with scikit-learn},
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| 770 |
+
url = {https://www.frontiersin.org/articles/10.3389/fninf.2014.00014/full},
|
| 771 |
+
volume = 8,
|
| 772 |
+
year = 2014
|
| 773 |
+
}
|
| 774 |
+
|
| 775 |
+
@article{lanczos,
|
| 776 |
+
author = {Lanczos, C.},
|
| 777 |
+
doi = {10.1137/0701007},
|
| 778 |
+
issn = {0887-459X},
|
| 779 |
+
journal = {Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis},
|
| 780 |
+
number = 1,
|
| 781 |
+
pages = {76-85},
|
| 782 |
+
title = {Evaluation of Noisy Data},
|
| 783 |
+
url = {http://epubs.siam.org/doi/10.1137/0701007},
|
| 784 |
+
volume = 1,
|
| 785 |
+
year = 1964
|
| 786 |
+
}
|
| 787 |
+
|
| 788 |
+
@article{compcor,
|
| 789 |
+
author = {Behzadi, Yashar and Restom, Khaled and Liau, Joy and Liu, Thomas T.},
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| 790 |
+
doi = {10.1016/j.neuroimage.2007.04.042},
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| 791 |
+
issn = {1053-8119},
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| 792 |
+
journal = {NeuroImage},
|
| 793 |
+
number = 1,
|
| 794 |
+
pages = {90-101},
|
| 795 |
+
title = {A component based noise correction method ({CompCor}) for {BOLD} and perfusion based fMRI},
|
| 796 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811907003837},
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| 797 |
+
volume = 37,
|
| 798 |
+
year = 2007
|
| 799 |
+
}
|
| 800 |
+
|
| 801 |
+
@article{hcppipelines,
|
| 802 |
+
author = {Glasser, Matthew F. and Sotiropoulos, Stamatios N. and Wilson, J. Anthony and Coalson, Timothy S. and Fischl, Bruce and Andersson, Jesper L. and Xu, Junqian and Jbabdi, Saad and Webster, Matthew and Polimeni, Jonathan R. and Van Essen, David C. and Jenkinson, Mark},
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| 803 |
+
doi = {10.1016/j.neuroimage.2013.04.127},
|
| 804 |
+
issn = {1053-8119},
|
| 805 |
+
journal = {NeuroImage},
|
| 806 |
+
pages = {105-124},
|
| 807 |
+
series = {Mapping the Connectome},
|
| 808 |
+
title = {The minimal preprocessing pipelines for the Human Connectome Project},
|
| 809 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913005053},
|
| 810 |
+
volume = 80,
|
| 811 |
+
year = 2013
|
| 812 |
+
}
|
| 813 |
+
|
| 814 |
+
@article{fs_template,
|
| 815 |
+
author = {Reuter, Martin and Rosas, Herminia Diana and Fischl, Bruce},
|
| 816 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
|
| 817 |
+
journal = {NeuroImage},
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| 818 |
+
number = 4,
|
| 819 |
+
pages = {1181-1196},
|
| 820 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
|
| 821 |
+
volume = 53,
|
| 822 |
+
year = 2010
|
| 823 |
+
}
|
| 824 |
+
|
| 825 |
+
@article{afni,
|
| 826 |
+
author = {Cox, Robert W. and Hyde, James S.},
|
| 827 |
+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
|
| 828 |
+
journal = {NMR in Biomedicine},
|
| 829 |
+
number = {4-5},
|
| 830 |
+
pages = {171-178},
|
| 831 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 832 |
+
volume = 10,
|
| 833 |
+
year = 1997
|
| 834 |
+
}
|
| 835 |
+
|
| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
+
function toggle(id) {
|
| 859 |
+
var element = document.getElementById(id);
|
| 860 |
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if(element.style.display == 'block')
|
| 861 |
+
element.style.display = 'none';
|
| 862 |
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else
|
| 863 |
+
element.style.display = 'block';
|
| 864 |
+
}
|
| 865 |
+
</script>
|
| 866 |
+
</body>
|
| 867 |
+
</html>
|
derivatives/fmriprep/sub-S15.html
ADDED
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|
| 15 |
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h1 { padding-top: 35px; }
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|
| 19 |
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|
| 26 |
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|
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|
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| 39 |
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|
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|
| 44 |
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|
| 46 |
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div#boilerplate pre {
|
| 47 |
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|
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|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
+
|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S15</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 192x256x128</li>
|
| 105 |
+
<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S15/figures/sub-S15_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S15/figures/sub-S15_dseg.svg" target="_blank">sub-S15/figures/sub-S15_dseg.svg</a>
|
| 115 |
+
</div>
|
| 116 |
+
|
| 117 |
+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S15/figures/sub-S15_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S15/figures/sub-S15_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S15/figures/sub-S15_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S15/figures/sub-S15_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_power2, csf_derivative1_power2, white_matter, white_matter_derivative1, white_matter_power2, white_matter_derivative1_power2, global_signal, global_signal_derivative1, global_signal_power2, global_signal_derivative1_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_derivative1_power2, trans_x_power2, trans_y, trans_y_derivative1, trans_y_derivative1_power2, trans_y_power2, trans_z, trans_z_derivative1, trans_z_derivative1_power2, trans_z_power2, rot_x, rot_x_derivative1, rot_x_power2, rot_x_derivative1_power2, rot_y, rot_y_derivative1, rot_y_power2, rot_y_derivative1_power2, rot_z, rot_z_derivative1, rot_z_derivative1_power2, rot_z_power2, motion_outlier00, motion_outlier01, motion_outlier02, motion_outlier03, motion_outlier04, motion_outlier05, motion_outlier06, motion_outlier07, motion_outlier08, motion_outlier09, motion_outlier10, motion_outlier11, motion_outlier12, motion_outlier13, motion_outlier14, motion_outlier15, motion_outlier16</li>
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<li>Non-steady-state volumes: 0</li>
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</ul>
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</div>
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<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
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<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
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<p class="elem-desc">
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The qform has been copied from sform.
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The difference in angle is 0.
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The difference in translation is 0.
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</p>
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<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
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<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S15/figures/sub-S15_task-localizer_desc-flirtbbr_bold.svg">
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Problem loading figure sub-S15/figures/sub-S15_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S15/figures/sub-S15_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S15/figures/sub-S15_task-localizer_desc-flirtbbr_bold.svg</a>
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<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
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<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S15/figures/sub-S15_task-localizer_desc-rois_bold.svg" style="width: 100%" />
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Get figure file: <a href="./sub-S15/figures/sub-S15_task-localizer_desc-rois_bold.svg" target="_blank">sub-S15/figures/sub-S15_task-localizer_desc-rois_bold.svg</a>
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</div>
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<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
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<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S15/figures/sub-S15_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
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<div class="elem-filename">
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Get figure file: <a href="./sub-S15/figures/sub-S15_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S15/figures/sub-S15_task-localizer_desc-compcorvar_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S15/figures/sub-S15_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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Get figure file: <a href="./sub-S15/figures/sub-S15_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S15/figures/sub-S15_task-localizer_desc-carpetplot_bold.svg</a>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S15/figures/sub-S15_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S15/figures/sub-S15_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S15/figures/sub-S15_task-localizer_desc-confoundcorr_bold.svg</a>
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</div>
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</div>
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</div>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S15 --nthreads 8 --omp-nthreads 8 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-12 13:42:50 -0400</li>
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</ul>
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</div>
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</div>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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</ul>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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</div>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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</div>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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</div>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
|
| 273 |
+
<div id="ref-lanczos">
|
| 274 |
+
<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
|
| 275 |
+
</div>
|
| 276 |
+
<div id="ref-power_fd_dvars">
|
| 277 |
+
<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
|
| 278 |
+
</div>
|
| 279 |
+
<div id="ref-confounds_satterthwaite_2013">
|
| 280 |
+
<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
|
| 281 |
+
</div>
|
| 282 |
+
<div id="ref-n4">
|
| 283 |
+
<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
|
| 284 |
+
</div>
|
| 285 |
+
<div id="ref-fsl_fast">
|
| 286 |
+
<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
|
| 287 |
+
</div>
|
| 288 |
+
</div></div></div>
|
| 289 |
+
<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
|
| 290 |
+
Results included in this manuscript come from preprocessing
|
| 291 |
+
performed using *fMRIPrep* 20.0.6
|
| 292 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 293 |
+
which is based on *Nipype* 1.4.2
|
| 294 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
|
| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
|
| 506 |
+
<pre>@article{fmriprep1,
|
| 507 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
|
| 508 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
|
| 509 |
+
year = {2018},
|
| 510 |
+
doi = {10.1038/s41592-018-0235-4},
|
| 511 |
+
journal = {Nature Methods}
|
| 512 |
+
}
|
| 513 |
+
|
| 514 |
+
@article{fmriprep2,
|
| 515 |
+
author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
|
| 516 |
+
title = {fMRIPrep},
|
| 517 |
+
year = 2018,
|
| 518 |
+
doi = {10.5281/zenodo.852659},
|
| 519 |
+
publisher = {Zenodo},
|
| 520 |
+
journal = {Software}
|
| 521 |
+
}
|
| 522 |
+
|
| 523 |
+
@article{nipype1,
|
| 524 |
+
author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
|
| 525 |
+
doi = {10.3389/fninf.2011.00013},
|
| 526 |
+
journal = {Frontiers in Neuroinformatics},
|
| 527 |
+
pages = 13,
|
| 528 |
+
shorttitle = {Nipype},
|
| 529 |
+
title = {Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in Python},
|
| 530 |
+
volume = 5,
|
| 531 |
+
year = 2011
|
| 532 |
+
}
|
| 533 |
+
|
| 534 |
+
@article{nipype2,
|
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journal = {NMR in Biomedicine},
|
| 829 |
+
number = {4-5},
|
| 830 |
+
pages = {171-178},
|
| 831 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 832 |
+
volume = 10,
|
| 833 |
+
year = 1997
|
| 834 |
+
}
|
| 835 |
+
|
| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
+
function toggle(id) {
|
| 859 |
+
var element = document.getElementById(id);
|
| 860 |
+
if(element.style.display == 'block')
|
| 861 |
+
element.style.display = 'none';
|
| 862 |
+
else
|
| 863 |
+
element.style.display = 'block';
|
| 864 |
+
}
|
| 865 |
+
</script>
|
| 866 |
+
</body>
|
| 867 |
+
</html>
|
derivatives/fmriprep/sub-S16.html
ADDED
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@@ -0,0 +1,867 @@
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#errors div, #errors p {
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padding-left: 1em;
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}
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</style>
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<body>
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<div class="collapse navbar-collapse">
|
| 62 |
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<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
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<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
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<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
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<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
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</div>
|
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+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
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+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
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+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
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</ul>
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</div>
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</nav>
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<noscript>
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<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
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</noscript>
|
| 80 |
+
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<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
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<ul class="elem-desc">
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| 85 |
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<li>Subject ID: S16</li>
|
| 86 |
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<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
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+
<ul class="elem-desc">
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| 89 |
+
<li>Task: localizer (1 run)</li>
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+
</ul>
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+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
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+
</ul>
|
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+
</div>
|
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+
</div>
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<div id="Anatomical">
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<h1 class="sub-report-title">Anatomical</h1>
|
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<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
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<h3 class="elem-title">Anatomical Conformation</h3>
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<ul class="elem-desc">
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+
<li>Input T1w images: 1</li>
|
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+
<li>Output orientation: RAS</li>
|
| 104 |
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<li>Output dimensions: 192x256x128</li>
|
| 105 |
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<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
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+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S16/figures/sub-S16_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
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+
Get figure file: <a href="./sub-S16/figures/sub-S16_dseg.svg" target="_blank">sub-S16/figures/sub-S16_dseg.svg</a>
|
| 115 |
+
</div>
|
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+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
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<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S16/figures/sub-S16_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S16/figures/sub-S16_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S16/figures/sub-S16_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S16/figures/sub-S16_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_derivative1_power2, csf_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_derivative1_power2, trans_x_power2, trans_y, trans_y_derivative1, trans_y_power2, trans_y_derivative1_power2, trans_z, trans_z_derivative1, trans_z_power2, trans_z_derivative1_power2, rot_x, rot_x_derivative1, rot_x_derivative1_power2, rot_x_power2, rot_y, rot_y_derivative1, rot_y_derivative1_power2, rot_y_power2, rot_z, rot_z_derivative1, rot_z_derivative1_power2, rot_z_power2, motion_outlier00</li>
|
| 139 |
+
<li>Non-steady-state volumes: 0</li>
|
| 140 |
+
</ul>
|
| 141 |
+
</div>
|
| 142 |
+
<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
|
| 143 |
+
<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
|
| 144 |
+
<p class="elem-desc">
|
| 145 |
+
The qform has been copied from sform.
|
| 146 |
+
The difference in angle is 0.
|
| 147 |
+
The difference in translation is 0.
|
| 148 |
+
</p>
|
| 149 |
+
</div>
|
| 150 |
+
<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
|
| 151 |
+
<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S16/figures/sub-S16_task-localizer_desc-flirtbbr_bold.svg">
|
| 152 |
+
Problem loading figure sub-S16/figures/sub-S16_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 153 |
+
</div>
|
| 154 |
+
<div class="elem-filename">
|
| 155 |
+
Get figure file: <a href="./sub-S16/figures/sub-S16_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S16/figures/sub-S16_task-localizer_desc-flirtbbr_bold.svg</a>
|
| 156 |
+
</div>
|
| 157 |
+
|
| 158 |
+
</div>
|
| 159 |
+
<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
|
| 160 |
+
<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S16/figures/sub-S16_task-localizer_desc-rois_bold.svg" style="width: 100%" />
|
| 161 |
+
</div>
|
| 162 |
+
<div class="elem-filename">
|
| 163 |
+
Get figure file: <a href="./sub-S16/figures/sub-S16_task-localizer_desc-rois_bold.svg" target="_blank">sub-S16/figures/sub-S16_task-localizer_desc-rois_bold.svg</a>
|
| 164 |
+
</div>
|
| 165 |
+
|
| 166 |
+
</div>
|
| 167 |
+
<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
|
| 168 |
+
<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S16/figures/sub-S16_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
|
| 169 |
+
</div>
|
| 170 |
+
<div class="elem-filename">
|
| 171 |
+
Get figure file: <a href="./sub-S16/figures/sub-S16_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S16/figures/sub-S16_task-localizer_desc-compcorvar_bold.svg</a>
|
| 172 |
+
</div>
|
| 173 |
+
|
| 174 |
+
</div>
|
| 175 |
+
<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
|
| 176 |
+
<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S16/figures/sub-S16_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
|
| 177 |
+
</div>
|
| 178 |
+
<div class="elem-filename">
|
| 179 |
+
Get figure file: <a href="./sub-S16/figures/sub-S16_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S16/figures/sub-S16_task-localizer_desc-carpetplot_bold.svg</a>
|
| 180 |
+
</div>
|
| 181 |
+
|
| 182 |
+
</div>
|
| 183 |
+
<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
|
| 184 |
+
<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
|
| 185 |
+
(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
|
| 186 |
+
Right: magnitude of the correlation between each confound time series and the
|
| 187 |
+
mean global signal. Strong correlations might be indicative of partial volume
|
| 188 |
+
effects and can inform decisions about feature orthogonalization prior to
|
| 189 |
+
confound regression.
|
| 190 |
+
</p> <img class="svg-reportlet" src="./sub-S16/figures/sub-S16_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
|
| 191 |
+
</div>
|
| 192 |
+
<div class="elem-filename">
|
| 193 |
+
Get figure file: <a href="./sub-S16/figures/sub-S16_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S16/figures/sub-S16_task-localizer_desc-confoundcorr_bold.svg</a>
|
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+
</div>
|
| 195 |
+
|
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+
</div>
|
| 197 |
+
</div>
|
| 198 |
+
<div id="About">
|
| 199 |
+
<h1 class="sub-report-title">About</h1>
|
| 200 |
+
<div id="datatype-anat_desc-about_suffix-T1w">
|
| 201 |
+
<ul>
|
| 202 |
+
<li>fMRIPrep version: 20.0.6</li>
|
| 203 |
+
<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S16 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
|
| 204 |
+
<li>Date preprocessed: 2020-05-12 16:04:04 -0400</li>
|
| 205 |
+
</ul>
|
| 206 |
+
</div>
|
| 207 |
+
</div>
|
| 208 |
+
</div>
|
| 209 |
+
|
| 210 |
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<div id="boilerplate">
|
| 211 |
+
<h1 class="sub-report-title">Methods</h1>
|
| 212 |
+
<p>We kindly ask to report results preprocessed with this tool using the following
|
| 213 |
+
boilerplate.</p>
|
| 214 |
+
<ul class="nav nav-tabs" id="myTab" role="tablist">
|
| 215 |
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<li class="nav-item">
|
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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+
<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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+
<dt>Functional data preprocessing</dt>
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+
<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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+
</dd>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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+
<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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| 240 |
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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</div>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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+
<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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</div>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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+
<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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+
<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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</div>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
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<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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</div>
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<div id="ref-power_fd_dvars">
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<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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</div>
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<div id="ref-confounds_satterthwaite_2013">
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<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
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</div>
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<div id="ref-n4">
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<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
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</div>
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<div id="ref-fsl_fast">
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<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
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</div>
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</div></div></div>
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<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
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+
Results included in this manuscript come from preprocessing
|
| 291 |
+
performed using *fMRIPrep* 20.0.6
|
| 292 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 293 |
+
which is based on *Nipype* 1.4.2
|
| 294 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
|
| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
|
| 506 |
+
<pre>@article{fmriprep1,
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| 507 |
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author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
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|
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address = {Berlin},
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author = {Huntenburg, Julia M.},
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language = {eng},
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school = {Freie Universität},
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title = {Evaluating nonlinear coregistration of {BOLD} {EPI} and T1w images},
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url = {http://hdl.handle.net/11858/00-001M-0000-002B-1CB5-A},
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year = 2014
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}
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journal = {PLOS ONE},
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+
number = 3,
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| 675 |
+
pages = {e0152472},
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+
title = {Characterization and Correction of Geometric Distortions in 814 Diffusion Weighted Images},
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url = {http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152472},
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+
volume = 11,
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+
year = 2016
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}
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@article{flirt,
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+
title = {A global optimisation method for robust affine registration of brain images},
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+
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+
url = {http://www.sciencedirect.com/science/article/pii/S1361841501000366},
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| 687 |
+
doi = {10.1016/S1361-8415(01)00036-6},
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| 689 |
+
urldate = {2018-07-27},
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+
journal = {Medical Image Analysis},
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+
author = {Jenkinson, Mark and Smith, Stephen},
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| 692 |
+
year = {2001},
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| 693 |
+
keywords = {Affine transformation, flirt, fsl, Global optimisation, Multi-resolution search, Multimodal registration, Robustness},
|
| 694 |
+
pages = {143--156}
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| 695 |
+
}
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| 696 |
+
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| 697 |
+
@article{mcflirt,
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| 698 |
+
author = {Jenkinson, Mark and Bannister, Peter and Brady, Michael and Smith, Stephen},
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| 699 |
+
doi = {10.1006/nimg.2002.1132},
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| 700 |
+
issn = {1053-8119},
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| 701 |
+
journal = {NeuroImage},
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| 702 |
+
number = 2,
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| 703 |
+
pages = {825-841},
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| 704 |
+
title = {Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images},
|
| 705 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811902911328},
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| 706 |
+
volume = 17,
|
| 707 |
+
year = 2002
|
| 708 |
+
}
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| 709 |
+
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| 710 |
+
@article{bbr,
|
| 711 |
+
author = {Greve, Douglas N and Fischl, Bruce},
|
| 712 |
+
doi = {10.1016/j.neuroimage.2009.06.060},
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| 713 |
+
issn = {1095-9572},
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| 714 |
+
journal = {NeuroImage},
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| 715 |
+
number = 1,
|
| 716 |
+
pages = {63-72},
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| 717 |
+
title = {Accurate and robust brain image alignment using boundary-based registration},
|
| 718 |
+
volume = 48,
|
| 719 |
+
year = 2009
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| 720 |
+
}
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| 721 |
+
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| 722 |
+
@article{aroma,
|
| 723 |
+
author = {Pruim, Raimon H. R. and Mennes, Maarten and van Rooij, Daan and Llera, Alberto and Buitelaar, Jan K. and Beckmann, Christian F.},
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| 724 |
+
doi = {10.1016/j.neuroimage.2015.02.064},
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| 725 |
+
issn = {1053-8119},
|
| 726 |
+
journal = {NeuroImage},
|
| 727 |
+
number = {Supplement C},
|
| 728 |
+
pages = {267-277},
|
| 729 |
+
shorttitle = {ICA-AROMA},
|
| 730 |
+
title = {ICA-{AROMA}: A robust {ICA}-based strategy for removing motion artifacts from fMRI data},
|
| 731 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811915001822},
|
| 732 |
+
volume = 112,
|
| 733 |
+
year = 2015
|
| 734 |
+
}
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| 735 |
+
|
| 736 |
+
@article{power_fd_dvars,
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| 737 |
+
author = {Power, Jonathan D. and Mitra, Anish and Laumann, Timothy O. and Snyder, Abraham Z. and Schlaggar, Bradley L. and Petersen, Steven E.},
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| 738 |
+
doi = {10.1016/j.neuroimage.2013.08.048},
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| 739 |
+
issn = {1053-8119},
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| 740 |
+
journal = {NeuroImage},
|
| 741 |
+
number = {Supplement C},
|
| 742 |
+
pages = {320-341},
|
| 743 |
+
title = {Methods to detect, characterize, and remove motion artifact in resting state fMRI},
|
| 744 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913009117},
|
| 745 |
+
volume = 84,
|
| 746 |
+
year = 2014
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| 747 |
+
}
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| 748 |
+
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| 749 |
+
@article{confounds_satterthwaite_2013,
|
| 750 |
+
author = {Satterthwaite, Theodore D. and Elliott, Mark A. and Gerraty, Raphael T. and Ruparel, Kosha and Loughead, James and Calkins, Monica E. and Eickhoff, Simon B. and Hakonarson, Hakon and Gur, Ruben C. and Gur, Raquel E. and Wolf, Daniel H.},
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| 751 |
+
doi = {10.1016/j.neuroimage.2012.08.052},
|
| 752 |
+
issn = {10538119},
|
| 753 |
+
journal = {NeuroImage},
|
| 754 |
+
number = 1,
|
| 755 |
+
pages = {240--256},
|
| 756 |
+
title = {{An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data}},
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| 757 |
+
url = {http://linkinghub.elsevier.com/retrieve/pii/S1053811912008609},
|
| 758 |
+
volume = 64,
|
| 759 |
+
year = 2013
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| 760 |
+
}
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| 761 |
+
|
| 762 |
+
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| 763 |
+
@article{nilearn,
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| 764 |
+
author = {Abraham, Alexandre and Pedregosa, Fabian and Eickenberg, Michael and Gervais, Philippe and Mueller, Andreas and Kossaifi, Jean and Gramfort, Alexandre and Thirion, Bertrand and Varoquaux, Gael},
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| 765 |
+
doi = {10.3389/fninf.2014.00014},
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| 766 |
+
issn = {1662-5196},
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| 767 |
+
journal = {Frontiers in Neuroinformatics},
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| 768 |
+
language = {English},
|
| 769 |
+
title = {Machine learning for neuroimaging with scikit-learn},
|
| 770 |
+
url = {https://www.frontiersin.org/articles/10.3389/fninf.2014.00014/full},
|
| 771 |
+
volume = 8,
|
| 772 |
+
year = 2014
|
| 773 |
+
}
|
| 774 |
+
|
| 775 |
+
@article{lanczos,
|
| 776 |
+
author = {Lanczos, C.},
|
| 777 |
+
doi = {10.1137/0701007},
|
| 778 |
+
issn = {0887-459X},
|
| 779 |
+
journal = {Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis},
|
| 780 |
+
number = 1,
|
| 781 |
+
pages = {76-85},
|
| 782 |
+
title = {Evaluation of Noisy Data},
|
| 783 |
+
url = {http://epubs.siam.org/doi/10.1137/0701007},
|
| 784 |
+
volume = 1,
|
| 785 |
+
year = 1964
|
| 786 |
+
}
|
| 787 |
+
|
| 788 |
+
@article{compcor,
|
| 789 |
+
author = {Behzadi, Yashar and Restom, Khaled and Liau, Joy and Liu, Thomas T.},
|
| 790 |
+
doi = {10.1016/j.neuroimage.2007.04.042},
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| 791 |
+
issn = {1053-8119},
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| 792 |
+
journal = {NeuroImage},
|
| 793 |
+
number = 1,
|
| 794 |
+
pages = {90-101},
|
| 795 |
+
title = {A component based noise correction method ({CompCor}) for {BOLD} and perfusion based fMRI},
|
| 796 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811907003837},
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| 797 |
+
volume = 37,
|
| 798 |
+
year = 2007
|
| 799 |
+
}
|
| 800 |
+
|
| 801 |
+
@article{hcppipelines,
|
| 802 |
+
author = {Glasser, Matthew F. and Sotiropoulos, Stamatios N. and Wilson, J. Anthony and Coalson, Timothy S. and Fischl, Bruce and Andersson, Jesper L. and Xu, Junqian and Jbabdi, Saad and Webster, Matthew and Polimeni, Jonathan R. and Van Essen, David C. and Jenkinson, Mark},
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| 803 |
+
doi = {10.1016/j.neuroimage.2013.04.127},
|
| 804 |
+
issn = {1053-8119},
|
| 805 |
+
journal = {NeuroImage},
|
| 806 |
+
pages = {105-124},
|
| 807 |
+
series = {Mapping the Connectome},
|
| 808 |
+
title = {The minimal preprocessing pipelines for the Human Connectome Project},
|
| 809 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913005053},
|
| 810 |
+
volume = 80,
|
| 811 |
+
year = 2013
|
| 812 |
+
}
|
| 813 |
+
|
| 814 |
+
@article{fs_template,
|
| 815 |
+
author = {Reuter, Martin and Rosas, Herminia Diana and Fischl, Bruce},
|
| 816 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
|
| 817 |
+
journal = {NeuroImage},
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| 818 |
+
number = 4,
|
| 819 |
+
pages = {1181-1196},
|
| 820 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
|
| 821 |
+
volume = 53,
|
| 822 |
+
year = 2010
|
| 823 |
+
}
|
| 824 |
+
|
| 825 |
+
@article{afni,
|
| 826 |
+
author = {Cox, Robert W. and Hyde, James S.},
|
| 827 |
+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
|
| 828 |
+
journal = {NMR in Biomedicine},
|
| 829 |
+
number = {4-5},
|
| 830 |
+
pages = {171-178},
|
| 831 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 832 |
+
volume = 10,
|
| 833 |
+
year = 1997
|
| 834 |
+
}
|
| 835 |
+
|
| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
+
function toggle(id) {
|
| 859 |
+
var element = document.getElementById(id);
|
| 860 |
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if(element.style.display == 'block')
|
| 861 |
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element.style.display = 'none';
|
| 862 |
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else
|
| 863 |
+
element.style.display = 'block';
|
| 864 |
+
}
|
| 865 |
+
</script>
|
| 866 |
+
</body>
|
| 867 |
+
</html>
|
derivatives/fmriprep/sub-S17.html
ADDED
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<style type="text/css">
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|
| 15 |
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h1 { padding-top: 35px; }
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| 16 |
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| 17 |
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| 18 |
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|
| 19 |
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| 21 |
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| 23 |
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|
| 24 |
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|
| 25 |
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|
| 26 |
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|
| 27 |
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| 29 |
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|
| 31 |
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| 32 |
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body {
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| 36 |
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| 37 |
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| 38 |
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|
| 39 |
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|
| 43 |
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|
| 44 |
+
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|
| 46 |
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div#boilerplate pre {
|
| 47 |
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margin: 20px 25px;
|
| 48 |
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|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
+
|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S17</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 192x256x128</li>
|
| 105 |
+
<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S17/figures/sub-S17_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S17/figures/sub-S17_dseg.svg" target="_blank">sub-S17/figures/sub-S17_dseg.svg</a>
|
| 115 |
+
</div>
|
| 116 |
+
|
| 117 |
+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S17/figures/sub-S17_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S17/figures/sub-S17_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S17/figures/sub-S17_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S17/figures/sub-S17_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
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<li>Confounds collected: csf, csf_derivative1, csf_power2, csf_derivative1_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_power2, trans_x_derivative1_power2, trans_y, trans_y_derivative1, trans_y_power2, trans_y_derivative1_power2, trans_z, trans_z_derivative1, trans_z_power2, trans_z_derivative1_power2, rot_x, rot_x_derivative1, rot_x_derivative1_power2, rot_x_power2, rot_y, rot_y_derivative1, rot_y_power2, rot_y_derivative1_power2, rot_z, rot_z_derivative1, rot_z_derivative1_power2, rot_z_power2, motion_outlier00, motion_outlier01, motion_outlier02, motion_outlier03, motion_outlier04</li>
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<li>Non-steady-state volumes: 0</li>
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</ul>
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</div>
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<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
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<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
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<p class="elem-desc">
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The qform has been copied from sform.
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The difference in angle is 0.
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The difference in translation is 0.
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</p>
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</div>
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<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
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<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S17/figures/sub-S17_task-localizer_desc-flirtbbr_bold.svg">
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Problem loading figure sub-S17/figures/sub-S17_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S17/figures/sub-S17_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S17/figures/sub-S17_task-localizer_desc-flirtbbr_bold.svg</a>
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<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
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<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S17/figures/sub-S17_task-localizer_desc-rois_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S17/figures/sub-S17_task-localizer_desc-rois_bold.svg" target="_blank">sub-S17/figures/sub-S17_task-localizer_desc-rois_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
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<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S17/figures/sub-S17_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
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<div class="elem-filename">
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Get figure file: <a href="./sub-S17/figures/sub-S17_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S17/figures/sub-S17_task-localizer_desc-compcorvar_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S17/figures/sub-S17_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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<div class="elem-filename">
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Get figure file: <a href="./sub-S17/figures/sub-S17_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S17/figures/sub-S17_task-localizer_desc-carpetplot_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S17/figures/sub-S17_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S17/figures/sub-S17_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S17/figures/sub-S17_task-localizer_desc-confoundcorr_bold.svg</a>
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</div>
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</div>
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</div>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S17 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-13 18:40:28 -0400</li>
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</ul>
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</div>
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</div>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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</li>
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</ul>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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</div>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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</div>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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</div>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
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<div id="ref-lanczos">
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<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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</div>
|
| 276 |
+
<div id="ref-power_fd_dvars">
|
| 277 |
+
<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
|
| 278 |
+
</div>
|
| 279 |
+
<div id="ref-confounds_satterthwaite_2013">
|
| 280 |
+
<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
|
| 281 |
+
</div>
|
| 282 |
+
<div id="ref-n4">
|
| 283 |
+
<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
|
| 284 |
+
</div>
|
| 285 |
+
<div id="ref-fsl_fast">
|
| 286 |
+
<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
|
| 287 |
+
</div>
|
| 288 |
+
</div></div></div>
|
| 289 |
+
<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
|
| 290 |
+
Results included in this manuscript come from preprocessing
|
| 291 |
+
performed using *fMRIPrep* 20.0.6
|
| 292 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 293 |
+
which is based on *Nipype* 1.4.2
|
| 294 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
|
| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
|
| 506 |
+
<pre>@article{fmriprep1,
|
| 507 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
|
| 508 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
|
| 509 |
+
year = {2018},
|
| 510 |
+
doi = {10.1038/s41592-018-0235-4},
|
| 511 |
+
journal = {Nature Methods}
|
| 512 |
+
}
|
| 513 |
+
|
| 514 |
+
@article{fmriprep2,
|
| 515 |
+
author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
|
| 516 |
+
title = {fMRIPrep},
|
| 517 |
+
year = 2018,
|
| 518 |
+
doi = {10.5281/zenodo.852659},
|
| 519 |
+
publisher = {Zenodo},
|
| 520 |
+
journal = {Software}
|
| 521 |
+
}
|
| 522 |
+
|
| 523 |
+
@article{nipype1,
|
| 524 |
+
author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
|
| 525 |
+
doi = {10.3389/fninf.2011.00013},
|
| 526 |
+
journal = {Frontiers in Neuroinformatics},
|
| 527 |
+
pages = 13,
|
| 528 |
+
shorttitle = {Nipype},
|
| 529 |
+
title = {Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in Python},
|
| 530 |
+
volume = 5,
|
| 531 |
+
year = 2011
|
| 532 |
+
}
|
| 533 |
+
|
| 534 |
+
@article{nipype2,
|
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+
journal = {NMR in Biomedicine},
|
| 829 |
+
number = {4-5},
|
| 830 |
+
pages = {171-178},
|
| 831 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 832 |
+
volume = 10,
|
| 833 |
+
year = 1997
|
| 834 |
+
}
|
| 835 |
+
|
| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
+
function toggle(id) {
|
| 859 |
+
var element = document.getElementById(id);
|
| 860 |
+
if(element.style.display == 'block')
|
| 861 |
+
element.style.display = 'none';
|
| 862 |
+
else
|
| 863 |
+
element.style.display = 'block';
|
| 864 |
+
}
|
| 865 |
+
</script>
|
| 866 |
+
</body>
|
| 867 |
+
</html>
|
derivatives/fmriprep/sub-S18.html
ADDED
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<div class="collapse navbar-collapse">
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<ul class="navbar-nav">
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<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
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<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
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<li class="nav-item dropdown">
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<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
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<div class="dropdown-menu" aria-labelledby="navbarFunctional">
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<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
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</div>
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</li>
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<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
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<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
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<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
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</ul>
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</noscript>
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<div id="Summary">
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| 82 |
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<h1 class="sub-report-title">Summary</h1>
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<div id="datatype-anat_desc-summary_suffix-T1w">
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<ul class="elem-desc">
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<li>Subject ID: S18</li>
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<li>Structural images: 1 T1-weighted </li>
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<li>Functional series: 1</li>
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<ul class="elem-desc">
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<li>Task: localizer (1 run)</li>
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</ul>
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<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
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<li>Non-standard output spaces: </li>
|
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+
<li>FreeSurfer reconstruction: Not run</li>
|
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</ul>
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</div>
|
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</div>
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<div id="Anatomical">
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<h1 class="sub-report-title">Anatomical</h1>
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<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
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<h3 class="elem-title">Anatomical Conformation</h3>
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<ul class="elem-desc">
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<li>Input T1w images: 1</li>
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<li>Output orientation: RAS</li>
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<li>Output dimensions: 160x240x256</li>
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<li>Output voxel size: 1.1mm x 1mm x 1mm</li>
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<li>Discarded images: 0</li>
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</ul>
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</div>
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<div id="datatype-anat_suffix-dseg">
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<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S18/figures/sub-S18_dseg.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S18/figures/sub-S18_dseg.svg" target="_blank">sub-S18/figures/sub-S18_dseg.svg</a>
|
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</div>
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</div>
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<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
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<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S18/figures/sub-S18_space-MNI152NLin2009cAsym_T1w.svg">
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| 120 |
+
Problem loading figure sub-S18/figures/sub-S18_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S18/figures/sub-S18_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S18/figures/sub-S18_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
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| 125 |
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|
| 126 |
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</div>
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| 127 |
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</div>
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<div id="Functional">
|
| 129 |
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<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_power2, csf_derivative1_power2, white_matter, white_matter_derivative1, white_matter_power2, white_matter_derivative1_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_derivative1_power2, trans_x_power2, trans_y, trans_y_derivative1, trans_y_derivative1_power2, trans_y_power2, trans_z, trans_z_derivative1, trans_z_power2, trans_z_derivative1_power2, rot_x, rot_x_derivative1, rot_x_power2, rot_x_derivative1_power2, rot_y, rot_y_derivative1, rot_y_power2, rot_y_derivative1_power2, rot_z, rot_z_derivative1, rot_z_derivative1_power2, rot_z_power2, motion_outlier00, motion_outlier01, motion_outlier02, motion_outlier03, motion_outlier04, motion_outlier05, motion_outlier06</li>
|
| 139 |
+
<li>Non-steady-state volumes: 0</li>
|
| 140 |
+
</ul>
|
| 141 |
+
</div>
|
| 142 |
+
<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
|
| 143 |
+
<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S18/figures/sub-S18_task-localizer_desc-flirtbbr_bold.svg">
|
| 144 |
+
Problem loading figure sub-S18/figures/sub-S18_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 145 |
+
</div>
|
| 146 |
+
<div class="elem-filename">
|
| 147 |
+
Get figure file: <a href="./sub-S18/figures/sub-S18_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S18/figures/sub-S18_task-localizer_desc-flirtbbr_bold.svg</a>
|
| 148 |
+
</div>
|
| 149 |
+
|
| 150 |
+
</div>
|
| 151 |
+
<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
|
| 152 |
+
<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S18/figures/sub-S18_task-localizer_desc-rois_bold.svg" style="width: 100%" />
|
| 153 |
+
</div>
|
| 154 |
+
<div class="elem-filename">
|
| 155 |
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Get figure file: <a href="./sub-S18/figures/sub-S18_task-localizer_desc-rois_bold.svg" target="_blank">sub-S18/figures/sub-S18_task-localizer_desc-rois_bold.svg</a>
|
| 156 |
+
</div>
|
| 157 |
+
|
| 158 |
+
</div>
|
| 159 |
+
<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
|
| 160 |
+
<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S18/figures/sub-S18_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
|
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+
</div>
|
| 162 |
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<div class="elem-filename">
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| 163 |
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Get figure file: <a href="./sub-S18/figures/sub-S18_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S18/figures/sub-S18_task-localizer_desc-compcorvar_bold.svg</a>
|
| 164 |
+
</div>
|
| 165 |
+
|
| 166 |
+
</div>
|
| 167 |
+
<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
|
| 168 |
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S18/figures/sub-S18_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
|
| 169 |
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</div>
|
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<div class="elem-filename">
|
| 171 |
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Get figure file: <a href="./sub-S18/figures/sub-S18_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S18/figures/sub-S18_task-localizer_desc-carpetplot_bold.svg</a>
|
| 172 |
+
</div>
|
| 173 |
+
|
| 174 |
+
</div>
|
| 175 |
+
<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
|
| 176 |
+
<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
|
| 177 |
+
(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
|
| 178 |
+
Right: magnitude of the correlation between each confound time series and the
|
| 179 |
+
mean global signal. Strong correlations might be indicative of partial volume
|
| 180 |
+
effects and can inform decisions about feature orthogonalization prior to
|
| 181 |
+
confound regression.
|
| 182 |
+
</p> <img class="svg-reportlet" src="./sub-S18/figures/sub-S18_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
|
| 183 |
+
</div>
|
| 184 |
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<div class="elem-filename">
|
| 185 |
+
Get figure file: <a href="./sub-S18/figures/sub-S18_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S18/figures/sub-S18_task-localizer_desc-confoundcorr_bold.svg</a>
|
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+
</div>
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|
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+
</div>
|
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+
</div>
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<div id="About">
|
| 191 |
+
<h1 class="sub-report-title">About</h1>
|
| 192 |
+
<div id="datatype-anat_desc-about_suffix-T1w">
|
| 193 |
+
<ul>
|
| 194 |
+
<li>fMRIPrep version: 20.0.6</li>
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| 195 |
+
<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S18 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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| 196 |
+
<li>Date preprocessed: 2020-05-12 13:47:46 -0400</li>
|
| 197 |
+
</ul>
|
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+
</div>
|
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</div>
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</div>
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<div id="boilerplate">
|
| 203 |
+
<h1 class="sub-report-title">Methods</h1>
|
| 204 |
+
<p>We kindly ask to report results preprocessed with this tool using the following
|
| 205 |
+
boilerplate.</p>
|
| 206 |
+
<ul class="nav nav-tabs" id="myTab" role="tablist">
|
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<li class="nav-item">
|
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
|
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</li>
|
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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+
<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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</div>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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</div>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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+
<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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+
<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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</div>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
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<div id="ref-lanczos">
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<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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</div>
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<div id="ref-power_fd_dvars">
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<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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</div>
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<div id="ref-confounds_satterthwaite_2013">
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<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
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</div>
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<div id="ref-n4">
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<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
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</div>
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<div id="ref-fsl_fast">
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<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
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</div>
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</div></div></div>
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<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
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Results included in this manuscript come from preprocessing
|
| 283 |
+
performed using *fMRIPrep* 20.0.6
|
| 284 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 285 |
+
which is based on *Nipype* 1.4.2
|
| 286 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 287 |
+
|
| 288 |
+
Anatomical data preprocessing
|
| 289 |
+
|
| 290 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 291 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 292 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 293 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 294 |
+
as target template.
|
| 295 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 296 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 297 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 298 |
+
@fsl_fast].
|
| 299 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 300 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 301 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 302 |
+
The following template was selected for spatial normalization:
|
| 303 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 304 |
+
|
| 305 |
+
Functional data preprocessing
|
| 306 |
+
|
| 307 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 308 |
+
tasks and sessions), the following preprocessing was performed.
|
| 309 |
+
First, a reference volume and its skull-stripped version were generated
|
| 310 |
+
using a custom methodology of *fMRIPrep*.
|
| 311 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 312 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 313 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 314 |
+
cost-function.
|
| 315 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 316 |
+
for distortions remaining in the BOLD reference.
|
| 317 |
+
Head-motion parameters with respect to the BOLD reference
|
| 318 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 319 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 320 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 321 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 322 |
+
were resampled onto their original, native space by applying
|
| 323 |
+
the transforms to correct for head-motion.
|
| 324 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 325 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 326 |
+
The BOLD time-series were resampled into standard space,
|
| 327 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 328 |
+
First, a reference volume and its skull-stripped version were generated
|
| 329 |
+
using a custom methodology of *fMRIPrep*.
|
| 330 |
+
Several confounding time-series were calculated based on the
|
| 331 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 332 |
+
three region-wise global signals.
|
| 333 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 334 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 335 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 336 |
+
the whole-brain masks.
|
| 337 |
+
Additionally, a set of physiological regressors were extracted to
|
| 338 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 339 |
+
Principal components are estimated after high-pass filtering the
|
| 340 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 341 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 342 |
+
and anatomical (aCompCor).
|
| 343 |
+
tCompCor components are then calculated from the top 5% variable
|
| 344 |
+
voxels within a mask covering the subcortical regions.
|
| 345 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 346 |
+
which ensures it does not include cortical GM regions.
|
| 347 |
+
For aCompCor, components are calculated within the intersection of
|
| 348 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 349 |
+
in T1w space, after their projection to the native space of each
|
| 350 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 351 |
+
are also calculated separately within the WM and CSF masks.
|
| 352 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 353 |
+
values are retained, such that the retained components' time series are
|
| 354 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 355 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 356 |
+
consideration.
|
| 357 |
+
The head-motion estimates calculated in the correction step were also
|
| 358 |
+
placed within the corresponding confounds file.
|
| 359 |
+
The confound time series derived from head motion estimates and global
|
| 360 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 361 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 362 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 363 |
+
were annotated as motion outliers.
|
| 364 |
+
All resamplings can be performed with *a single interpolation
|
| 365 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 366 |
+
transform matrices, susceptibility distortion correction when available,
|
| 367 |
+
and co-registrations to anatomical and output spaces).
|
| 368 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 369 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 370 |
+
effects of other kernels [@lanczos].
|
| 371 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 372 |
+
(FreeSurfer).
|
| 373 |
+
|
| 374 |
+
|
| 375 |
+
Many internal operations of *fMRIPrep* use
|
| 376 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 377 |
+
mostly within the functional processing workflow.
|
| 378 |
+
For more details of the pipeline, see [the section corresponding
|
| 379 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 380 |
+
|
| 381 |
+
|
| 382 |
+
### Copyright Waiver
|
| 383 |
+
|
| 384 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 385 |
+
with the express intention that users should copy and paste this
|
| 386 |
+
text into their manuscripts *unchanged*.
|
| 387 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 388 |
+
|
| 389 |
+
### References
|
| 390 |
+
|
| 391 |
+
</pre>
|
| 392 |
+
</div>
|
| 393 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 394 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 395 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 396 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 397 |
+
|
| 398 |
+
\begin{description}
|
| 399 |
+
\item[Anatomical data preprocessing]
|
| 400 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 401 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 402 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 403 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 404 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 405 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 406 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 407 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 408 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 409 |
+
Volume-based spatial normalization to one standard space
|
| 410 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 411 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 412 |
+
of both T1w reference and the T1w template. The following template was
|
| 413 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 414 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 415 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 416 |
+
\item[Functional data preprocessing]
|
| 417 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 418 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 419 |
+
volume and its skull-stripped version were generated using a custom
|
| 420 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 421 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 422 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 423 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 424 |
+
was configured with nine degrees of freedom to account for distortions
|
| 425 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 426 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 427 |
+
rotation and translation parameters) are estimated before any
|
| 428 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 429 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 430 |
+
correction when applied) were resampled onto their original, native
|
| 431 |
+
space by applying the transforms to correct for head-motion. These
|
| 432 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 433 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 434 |
+
time-series were resampled into standard space, generating a
|
| 435 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 436 |
+
reference volume and its skull-stripped version were generated using a
|
| 437 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 438 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 439 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 440 |
+
DVARS are calculated for each functional run, both using their
|
| 441 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 442 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 443 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 444 |
+
physiological regressors were extracted to allow for component-based
|
| 445 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 446 |
+
components are estimated after high-pass filtering the
|
| 447 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 448 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 449 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 450 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 451 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 452 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 453 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 454 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 455 |
+
in T1w space, after their projection to the native space of each
|
| 456 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 457 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 458 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 459 |
+
singular values are retained, such that the retained components' time
|
| 460 |
+
series are sufficient to explain 50 percent of variance across the
|
| 461 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 462 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 463 |
+
the correction step were also placed within the corresponding confounds
|
| 464 |
+
file. The confound time series derived from head motion estimates and
|
| 465 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 466 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 467 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 468 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 469 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 470 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 471 |
+
distortion correction when available, and co-registrations to anatomical
|
| 472 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 473 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 474 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 475 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 476 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 477 |
+
\end{description}
|
| 478 |
+
|
| 479 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 480 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 481 |
+
processing workflow. For more details of the pipeline, see
|
| 482 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 483 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 484 |
+
|
| 485 |
+
\hypertarget{copyright-waiver}{%
|
| 486 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 487 |
+
|
| 488 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 489 |
+
the express intention that users should copy and paste this text into
|
| 490 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 491 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 492 |
+
|
| 493 |
+
\hypertarget{references}{%
|
| 494 |
+
\subsubsection{References}\label{references}}
|
| 495 |
+
|
| 496 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 497 |
+
<h3>Bibliography</h3>
|
| 498 |
+
<pre>@article{fmriprep1,
|
| 499 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
|
| 500 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
|
| 501 |
+
year = {2018},
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| 502 |
+
doi = {10.1038/s41592-018-0235-4},
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| 503 |
+
journal = {Nature Methods}
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| 504 |
+
}
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| 505 |
+
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| 506 |
+
@article{fmriprep2,
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| 507 |
+
author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
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| 508 |
+
title = {fMRIPrep},
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| 509 |
+
year = 2018,
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| 510 |
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doi = {10.5281/zenodo.852659},
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| 511 |
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publisher = {Zenodo},
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| 512 |
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journal = {Software}
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| 513 |
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}
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@article{nipype1,
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+
author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
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+
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| 518 |
+
journal = {Frontiers in Neuroinformatics},
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| 519 |
+
pages = 13,
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| 520 |
+
shorttitle = {Nipype},
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| 521 |
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title = {Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in Python},
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|
| 528 |
+
title = {Nipype},
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| 529 |
+
year = 2018,
|
| 530 |
+
doi = {10.5281/zenodo.596855},
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+
publisher = {Zenodo},
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+
journal = {Software}
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| 533 |
+
}
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+
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+
@article{n4,
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author = {Tustison, N. J. and Avants, B. B. and Cook, P. A. and Zheng, Y. and Egan, A. and Yushkevich, P. A. and Gee, J. C.},
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doi = {10.1109/TMI.2010.2046908},
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issn = {0278-0062},
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journal = {IEEE Transactions on Medical Imaging},
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number = 6,
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| 541 |
+
pages = {1310-1320},
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shorttitle = {N4ITK},
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title = {N4ITK: Improved N3 Bias Correction},
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+
volume = 29,
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+
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}
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pages = {179-194},
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title = {Cortical Surface-Based Analysis: I. Segmentation and Surface Reconstruction},
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+
author = {Klein, Arno and Ghosh, Satrajit S. and Bao, Forrest S. and Giard, Joachim and Häme, Yrjö and Stavsky, Eliezer and Lee, Noah and Rossa, Brian and Reuter, Martin and Neto, Elias Chaibub and Keshavan, Anisha},
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number = 2,
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+
pages = {e1005350},
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+
title = {Mindboggling morphometry of human brains},
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+
url = {http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005350},
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+
volume = 13,
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+
}
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+
|
| 577 |
+
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+
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+
author = {Mazziotta, John C. and Toga, Arthur W. and Evans, Alan and Fox, Peter and Lancaster, Jack},
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| 580 |
+
volume = {2},
|
| 581 |
+
issn = {1053-8119},
|
| 582 |
+
shorttitle = {A {Probabilistic} {Atlas} of the {Human} {Brain}},
|
| 583 |
+
doi = {10.1006/nimg.1995.1012},
|
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}
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|
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+
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|
| 591 |
+
title = {Unbiased nonlinear average age-appropriate brain templates from birth to adulthood},
|
| 592 |
+
author = {Fonov, VS and Evans, AC and McKinstry, RC and Almli, CR and Collins, DL},
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doi = {10.1016/S1053-8119(09)70884-5},
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|
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+
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title = {Evaluation of Field Map and Nonlinear Registration Methods for Correction of Susceptibility Artifacts in Diffusion {MRI}},
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@phdthesis{fieldmapless2,
|
| 651 |
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address = {Berlin},
|
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+
author = {Huntenburg, Julia M.},
|
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+
language = {eng},
|
| 654 |
+
school = {Freie Universität},
|
| 655 |
+
title = {Evaluating nonlinear coregistration of {BOLD} {EPI} and T1w images},
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type = {Master's Thesis},
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url = {http://hdl.handle.net/11858/00-001M-0000-002B-1CB5-A},
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year = 2014
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}
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@article{fieldmapless3,
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number = 3,
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pages = {e0152472},
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| 668 |
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title = {Characterization and Correction of Geometric Distortions in 814 Diffusion Weighted Images},
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volume = 11,
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}
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| 673 |
+
|
| 674 |
+
@article{flirt,
|
| 675 |
+
title = {A global optimisation method for robust affine registration of brain images},
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| 676 |
+
volume = {5},
|
| 677 |
+
issn = {1361-8415},
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| 678 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1361841501000366},
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| 679 |
+
doi = {10.1016/S1361-8415(01)00036-6},
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| 680 |
+
number = {2},
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| 681 |
+
urldate = {2018-07-27},
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| 682 |
+
journal = {Medical Image Analysis},
|
| 683 |
+
author = {Jenkinson, Mark and Smith, Stephen},
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| 684 |
+
year = {2001},
|
| 685 |
+
keywords = {Affine transformation, flirt, fsl, Global optimisation, Multi-resolution search, Multimodal registration, Robustness},
|
| 686 |
+
pages = {143--156}
|
| 687 |
+
}
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| 688 |
+
|
| 689 |
+
@article{mcflirt,
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| 690 |
+
author = {Jenkinson, Mark and Bannister, Peter and Brady, Michael and Smith, Stephen},
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| 691 |
+
doi = {10.1006/nimg.2002.1132},
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| 692 |
+
issn = {1053-8119},
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| 693 |
+
journal = {NeuroImage},
|
| 694 |
+
number = 2,
|
| 695 |
+
pages = {825-841},
|
| 696 |
+
title = {Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images},
|
| 697 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811902911328},
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| 698 |
+
volume = 17,
|
| 699 |
+
year = 2002
|
| 700 |
+
}
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| 701 |
+
|
| 702 |
+
@article{bbr,
|
| 703 |
+
author = {Greve, Douglas N and Fischl, Bruce},
|
| 704 |
+
doi = {10.1016/j.neuroimage.2009.06.060},
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| 705 |
+
issn = {1095-9572},
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| 706 |
+
journal = {NeuroImage},
|
| 707 |
+
number = 1,
|
| 708 |
+
pages = {63-72},
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| 709 |
+
title = {Accurate and robust brain image alignment using boundary-based registration},
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| 710 |
+
volume = 48,
|
| 711 |
+
year = 2009
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| 712 |
+
}
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| 713 |
+
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| 714 |
+
@article{aroma,
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| 715 |
+
author = {Pruim, Raimon H. R. and Mennes, Maarten and van Rooij, Daan and Llera, Alberto and Buitelaar, Jan K. and Beckmann, Christian F.},
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| 716 |
+
doi = {10.1016/j.neuroimage.2015.02.064},
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| 717 |
+
issn = {1053-8119},
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| 718 |
+
journal = {NeuroImage},
|
| 719 |
+
number = {Supplement C},
|
| 720 |
+
pages = {267-277},
|
| 721 |
+
shorttitle = {ICA-AROMA},
|
| 722 |
+
title = {ICA-{AROMA}: A robust {ICA}-based strategy for removing motion artifacts from fMRI data},
|
| 723 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811915001822},
|
| 724 |
+
volume = 112,
|
| 725 |
+
year = 2015
|
| 726 |
+
}
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| 727 |
+
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| 728 |
+
@article{power_fd_dvars,
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| 729 |
+
author = {Power, Jonathan D. and Mitra, Anish and Laumann, Timothy O. and Snyder, Abraham Z. and Schlaggar, Bradley L. and Petersen, Steven E.},
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| 730 |
+
doi = {10.1016/j.neuroimage.2013.08.048},
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| 731 |
+
issn = {1053-8119},
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| 732 |
+
journal = {NeuroImage},
|
| 733 |
+
number = {Supplement C},
|
| 734 |
+
pages = {320-341},
|
| 735 |
+
title = {Methods to detect, characterize, and remove motion artifact in resting state fMRI},
|
| 736 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913009117},
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| 737 |
+
volume = 84,
|
| 738 |
+
year = 2014
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| 739 |
+
}
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| 740 |
+
|
| 741 |
+
@article{confounds_satterthwaite_2013,
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| 742 |
+
author = {Satterthwaite, Theodore D. and Elliott, Mark A. and Gerraty, Raphael T. and Ruparel, Kosha and Loughead, James and Calkins, Monica E. and Eickhoff, Simon B. and Hakonarson, Hakon and Gur, Ruben C. and Gur, Raquel E. and Wolf, Daniel H.},
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| 743 |
+
doi = {10.1016/j.neuroimage.2012.08.052},
|
| 744 |
+
issn = {10538119},
|
| 745 |
+
journal = {NeuroImage},
|
| 746 |
+
number = 1,
|
| 747 |
+
pages = {240--256},
|
| 748 |
+
title = {{An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data}},
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| 749 |
+
url = {http://linkinghub.elsevier.com/retrieve/pii/S1053811912008609},
|
| 750 |
+
volume = 64,
|
| 751 |
+
year = 2013
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| 752 |
+
}
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| 753 |
+
|
| 754 |
+
|
| 755 |
+
@article{nilearn,
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| 756 |
+
author = {Abraham, Alexandre and Pedregosa, Fabian and Eickenberg, Michael and Gervais, Philippe and Mueller, Andreas and Kossaifi, Jean and Gramfort, Alexandre and Thirion, Bertrand and Varoquaux, Gael},
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| 757 |
+
doi = {10.3389/fninf.2014.00014},
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| 758 |
+
issn = {1662-5196},
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| 759 |
+
journal = {Frontiers in Neuroinformatics},
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| 760 |
+
language = {English},
|
| 761 |
+
title = {Machine learning for neuroimaging with scikit-learn},
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| 762 |
+
url = {https://www.frontiersin.org/articles/10.3389/fninf.2014.00014/full},
|
| 763 |
+
volume = 8,
|
| 764 |
+
year = 2014
|
| 765 |
+
}
|
| 766 |
+
|
| 767 |
+
@article{lanczos,
|
| 768 |
+
author = {Lanczos, C.},
|
| 769 |
+
doi = {10.1137/0701007},
|
| 770 |
+
issn = {0887-459X},
|
| 771 |
+
journal = {Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis},
|
| 772 |
+
number = 1,
|
| 773 |
+
pages = {76-85},
|
| 774 |
+
title = {Evaluation of Noisy Data},
|
| 775 |
+
url = {http://epubs.siam.org/doi/10.1137/0701007},
|
| 776 |
+
volume = 1,
|
| 777 |
+
year = 1964
|
| 778 |
+
}
|
| 779 |
+
|
| 780 |
+
@article{compcor,
|
| 781 |
+
author = {Behzadi, Yashar and Restom, Khaled and Liau, Joy and Liu, Thomas T.},
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| 782 |
+
doi = {10.1016/j.neuroimage.2007.04.042},
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| 783 |
+
issn = {1053-8119},
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| 784 |
+
journal = {NeuroImage},
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| 785 |
+
number = 1,
|
| 786 |
+
pages = {90-101},
|
| 787 |
+
title = {A component based noise correction method ({CompCor}) for {BOLD} and perfusion based fMRI},
|
| 788 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811907003837},
|
| 789 |
+
volume = 37,
|
| 790 |
+
year = 2007
|
| 791 |
+
}
|
| 792 |
+
|
| 793 |
+
@article{hcppipelines,
|
| 794 |
+
author = {Glasser, Matthew F. and Sotiropoulos, Stamatios N. and Wilson, J. Anthony and Coalson, Timothy S. and Fischl, Bruce and Andersson, Jesper L. and Xu, Junqian and Jbabdi, Saad and Webster, Matthew and Polimeni, Jonathan R. and Van Essen, David C. and Jenkinson, Mark},
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| 795 |
+
doi = {10.1016/j.neuroimage.2013.04.127},
|
| 796 |
+
issn = {1053-8119},
|
| 797 |
+
journal = {NeuroImage},
|
| 798 |
+
pages = {105-124},
|
| 799 |
+
series = {Mapping the Connectome},
|
| 800 |
+
title = {The minimal preprocessing pipelines for the Human Connectome Project},
|
| 801 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913005053},
|
| 802 |
+
volume = 80,
|
| 803 |
+
year = 2013
|
| 804 |
+
}
|
| 805 |
+
|
| 806 |
+
@article{fs_template,
|
| 807 |
+
author = {Reuter, Martin and Rosas, Herminia Diana and Fischl, Bruce},
|
| 808 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
|
| 809 |
+
journal = {NeuroImage},
|
| 810 |
+
number = 4,
|
| 811 |
+
pages = {1181-1196},
|
| 812 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
|
| 813 |
+
volume = 53,
|
| 814 |
+
year = 2010
|
| 815 |
+
}
|
| 816 |
+
|
| 817 |
+
@article{afni,
|
| 818 |
+
author = {Cox, Robert W. and Hyde, James S.},
|
| 819 |
+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
|
| 820 |
+
journal = {NMR in Biomedicine},
|
| 821 |
+
number = {4-5},
|
| 822 |
+
pages = {171-178},
|
| 823 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 824 |
+
volume = 10,
|
| 825 |
+
year = 1997
|
| 826 |
+
}
|
| 827 |
+
|
| 828 |
+
@article{posse_t2s,
|
| 829 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 830 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 831 |
+
journal = {Magnetic Resonance in Medicine},
|
| 832 |
+
number = 1,
|
| 833 |
+
pages = {87-97},
|
| 834 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 835 |
+
volume = 42,
|
| 836 |
+
year = 1999
|
| 837 |
+
}
|
| 838 |
+
</pre>
|
| 839 |
+
</div>
|
| 840 |
+
</div>
|
| 841 |
+
</div>
|
| 842 |
+
|
| 843 |
+
<div id="errors">
|
| 844 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 845 |
+
<p>No errors to report!</p>
|
| 846 |
+
</div>
|
| 847 |
+
|
| 848 |
+
|
| 849 |
+
<script type="text/javascript">
|
| 850 |
+
function toggle(id) {
|
| 851 |
+
var element = document.getElementById(id);
|
| 852 |
+
if(element.style.display == 'block')
|
| 853 |
+
element.style.display = 'none';
|
| 854 |
+
else
|
| 855 |
+
element.style.display = 'block';
|
| 856 |
+
}
|
| 857 |
+
</script>
|
| 858 |
+
</body>
|
| 859 |
+
</html>
|
derivatives/fmriprep/sub-S19.html
ADDED
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|
| 15 |
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h1 { padding-top: 35px; }
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|
| 19 |
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| 25 |
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|
| 26 |
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|
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|
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| 39 |
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|
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| 44 |
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|
| 46 |
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div#boilerplate pre {
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| 47 |
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|
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|
| 49 |
+
background-color: #F8F9FA;
|
| 50 |
+
}
|
| 51 |
+
|
| 52 |
+
#errors div, #errors p {
|
| 53 |
+
padding-left: 1em;
|
| 54 |
+
}
|
| 55 |
+
</style>
|
| 56 |
+
</head>
|
| 57 |
+
<body>
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
|
| 61 |
+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
| 73 |
+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
| 74 |
+
</ul>
|
| 75 |
+
</div>
|
| 76 |
+
</nav>
|
| 77 |
+
<noscript>
|
| 78 |
+
<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
|
| 79 |
+
</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S19</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
| 95 |
+
</div>
|
| 96 |
+
</div>
|
| 97 |
+
<div id="Anatomical">
|
| 98 |
+
<h1 class="sub-report-title">Anatomical</h1>
|
| 99 |
+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
|
| 100 |
+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 192x256x128</li>
|
| 105 |
+
<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S19/figures/sub-S19_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
| 114 |
+
Get figure file: <a href="./sub-S19/figures/sub-S19_dseg.svg" target="_blank">sub-S19/figures/sub-S19_dseg.svg</a>
|
| 115 |
+
</div>
|
| 116 |
+
|
| 117 |
+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S19/figures/sub-S19_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S19/figures/sub-S19_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S19/figures/sub-S19_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S19/figures/sub-S19_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_derivative1_power2, csf_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, t_comp_cor_04, t_comp_cor_05, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, a_comp_cor_84, a_comp_cor_85, a_comp_cor_86, a_comp_cor_87, a_comp_cor_88, a_comp_cor_89, a_comp_cor_90, a_comp_cor_91, a_comp_cor_92, a_comp_cor_93, a_comp_cor_94, a_comp_cor_95, a_comp_cor_96, a_comp_cor_97, a_comp_cor_98, a_comp_cor_99, a_comp_cor_100, a_comp_cor_101, a_comp_cor_102, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_power2, trans_x_derivative1_power2, trans_y, trans_y_derivative1, trans_y_derivative1_power2, trans_y_power2, trans_z, trans_z_derivative1, trans_z_power2, trans_z_derivative1_power2, rot_x, rot_x_derivative1, rot_x_power2, rot_x_derivative1_power2, rot_y, rot_y_derivative1, rot_y_derivative1_power2, rot_y_power2, rot_z, rot_z_derivative1, rot_z_power2, rot_z_derivative1_power2</li>
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<li>Non-steady-state volumes: 0</li>
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</ul>
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</div>
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<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
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<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
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<p class="elem-desc">
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The qform has been copied from sform.
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The difference in angle is 0.
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The difference in translation is 0.
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</p>
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</div>
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<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
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<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S19/figures/sub-S19_task-localizer_desc-flirtbbr_bold.svg">
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Problem loading figure sub-S19/figures/sub-S19_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S19/figures/sub-S19_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S19/figures/sub-S19_task-localizer_desc-flirtbbr_bold.svg</a>
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<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
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<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S19/figures/sub-S19_task-localizer_desc-rois_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S19/figures/sub-S19_task-localizer_desc-rois_bold.svg" target="_blank">sub-S19/figures/sub-S19_task-localizer_desc-rois_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
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<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S19/figures/sub-S19_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
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<div class="elem-filename">
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Get figure file: <a href="./sub-S19/figures/sub-S19_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S19/figures/sub-S19_task-localizer_desc-compcorvar_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
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<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S19/figures/sub-S19_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
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<div class="elem-filename">
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Get figure file: <a href="./sub-S19/figures/sub-S19_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S19/figures/sub-S19_task-localizer_desc-carpetplot_bold.svg</a>
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</div>
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</div>
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<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
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<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
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(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
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Right: magnitude of the correlation between each confound time series and the
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mean global signal. Strong correlations might be indicative of partial volume
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effects and can inform decisions about feature orthogonalization prior to
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confound regression.
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</p> <img class="svg-reportlet" src="./sub-S19/figures/sub-S19_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
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</div>
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<div class="elem-filename">
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Get figure file: <a href="./sub-S19/figures/sub-S19_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S19/figures/sub-S19_task-localizer_desc-confoundcorr_bold.svg</a>
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</div>
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</div>
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</div>
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<div id="About">
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<h1 class="sub-report-title">About</h1>
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<div id="datatype-anat_desc-about_suffix-T1w">
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<ul>
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<li>fMRIPrep version: 20.0.6</li>
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<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S19 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
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<li>Date preprocessed: 2020-05-12 13:47:46 -0400</li>
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</ul>
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</div>
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</div>
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</div>
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<div id="boilerplate">
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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+
boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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</li>
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</ul>
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<div class="tab-content" id="myTabContent">
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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<dt>Functional data preprocessing</dt>
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<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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</div>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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</div>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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| 268 |
+
<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
|
| 269 |
+
</div>
|
| 270 |
+
<div id="ref-flirt">
|
| 271 |
+
<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
|
| 272 |
+
</div>
|
| 273 |
+
<div id="ref-lanczos">
|
| 274 |
+
<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
|
| 275 |
+
</div>
|
| 276 |
+
<div id="ref-power_fd_dvars">
|
| 277 |
+
<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
|
| 278 |
+
</div>
|
| 279 |
+
<div id="ref-confounds_satterthwaite_2013">
|
| 280 |
+
<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
|
| 281 |
+
</div>
|
| 282 |
+
<div id="ref-n4">
|
| 283 |
+
<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
|
| 284 |
+
</div>
|
| 285 |
+
<div id="ref-fsl_fast">
|
| 286 |
+
<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
|
| 287 |
+
</div>
|
| 288 |
+
</div></div></div>
|
| 289 |
+
<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
|
| 290 |
+
Results included in this manuscript come from preprocessing
|
| 291 |
+
performed using *fMRIPrep* 20.0.6
|
| 292 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 293 |
+
which is based on *Nipype* 1.4.2
|
| 294 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
|
| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
|
| 506 |
+
<pre>@article{fmriprep1,
|
| 507 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
|
| 508 |
+
title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
|
| 509 |
+
year = {2018},
|
| 510 |
+
doi = {10.1038/s41592-018-0235-4},
|
| 511 |
+
journal = {Nature Methods}
|
| 512 |
+
}
|
| 513 |
+
|
| 514 |
+
@article{fmriprep2,
|
| 515 |
+
author = {Esteban, Oscar and Blair, Ross and Markiewicz, Christopher J. and Berleant, Shoshana L. and Moodie, Craig and Ma, Feilong and Isik, Ayse Ilkay and Erramuzpe, Asier and Kent, James D. andGoncalves, Mathias and DuPre, Elizabeth and Sitek, Kevin R. and Gomez, Daniel E. P. and Lurie, Daniel J. and Ye, Zhifang and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
|
| 516 |
+
title = {fMRIPrep},
|
| 517 |
+
year = 2018,
|
| 518 |
+
doi = {10.5281/zenodo.852659},
|
| 519 |
+
publisher = {Zenodo},
|
| 520 |
+
journal = {Software}
|
| 521 |
+
}
|
| 522 |
+
|
| 523 |
+
@article{nipype1,
|
| 524 |
+
author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
|
| 525 |
+
doi = {10.3389/fninf.2011.00013},
|
| 526 |
+
journal = {Frontiers in Neuroinformatics},
|
| 527 |
+
pages = 13,
|
| 528 |
+
shorttitle = {Nipype},
|
| 529 |
+
title = {Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in Python},
|
| 530 |
+
volume = 5,
|
| 531 |
+
year = 2011
|
| 532 |
+
}
|
| 533 |
+
|
| 534 |
+
@article{nipype2,
|
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journal = {NMR in Biomedicine},
|
| 829 |
+
number = {4-5},
|
| 830 |
+
pages = {171-178},
|
| 831 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 832 |
+
volume = 10,
|
| 833 |
+
year = 1997
|
| 834 |
+
}
|
| 835 |
+
|
| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
+
function toggle(id) {
|
| 859 |
+
var element = document.getElementById(id);
|
| 860 |
+
if(element.style.display == 'block')
|
| 861 |
+
element.style.display = 'none';
|
| 862 |
+
else
|
| 863 |
+
element.style.display = 'block';
|
| 864 |
+
}
|
| 865 |
+
</script>
|
| 866 |
+
</body>
|
| 867 |
+
</html>
|
derivatives/fmriprep/sub-S19/anat/sub-S19_desc-preproc_T1w.json
ADDED
|
@@ -0,0 +1,3 @@
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| 1 |
+
{
|
| 2 |
+
"SkullStripped": false
|
| 3 |
+
}
|
derivatives/fmriprep/sub-S20.html
ADDED
|
@@ -0,0 +1,867 @@
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}
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#errors div, #errors p {
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padding-left: 1em;
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}
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</style>
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</head>
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<body>
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<nav class="navbar fixed-top navbar-expand-lg navbar-light bg-light">
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+
<div class="collapse navbar-collapse">
|
| 62 |
+
<ul class="navbar-nav">
|
| 63 |
+
<li class="nav-item"><a class="nav-link" href="#Summary">Summary</a></li>
|
| 64 |
+
<li class="nav-item"><a class="nav-link" href="#Anatomical">Anatomical</a></li>
|
| 65 |
+
<li class="nav-item dropdown">
|
| 66 |
+
<a class="nav-link dropdown-toggle" id="navbarFunctional" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">Functional</a>
|
| 67 |
+
<div class="dropdown-menu" aria-labelledby="navbarFunctional">
|
| 68 |
+
<a class="dropdown-item" href="#datatype-func_desc-summary_suffix-bold_task-localizer">Reports for: task <span class="bids-entity">localizer</span>.</a>
|
| 69 |
+
</div>
|
| 70 |
+
</li>
|
| 71 |
+
<li class="nav-item"><a class="nav-link" href="#About">About</a></li>
|
| 72 |
+
<li class="nav-item"><a class="nav-link" href="#boilerplate">Methods</a></li>
|
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+
<li class="nav-item"><a class="nav-link" href="#errors">Errors</a></li>
|
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</ul>
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</div>
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</nav>
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<noscript>
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<h1 class="text-danger"> The navigation menu uses Javascript. Without it this report might not work as expected </h1>
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</noscript>
|
| 80 |
+
|
| 81 |
+
<div id="Summary">
|
| 82 |
+
<h1 class="sub-report-title">Summary</h1>
|
| 83 |
+
<div id="datatype-anat_desc-summary_suffix-T1w">
|
| 84 |
+
<ul class="elem-desc">
|
| 85 |
+
<li>Subject ID: S20</li>
|
| 86 |
+
<li>Structural images: 1 T1-weighted </li>
|
| 87 |
+
<li>Functional series: 1</li>
|
| 88 |
+
<ul class="elem-desc">
|
| 89 |
+
<li>Task: localizer (1 run)</li>
|
| 90 |
+
</ul>
|
| 91 |
+
<li>Standard output spaces: MNI152NLin2009cAsym</li>
|
| 92 |
+
<li>Non-standard output spaces: </li>
|
| 93 |
+
<li>FreeSurfer reconstruction: Not run</li>
|
| 94 |
+
</ul>
|
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+
</div>
|
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+
</div>
|
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<div id="Anatomical">
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+
<h1 class="sub-report-title">Anatomical</h1>
|
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+
<div id="datatype-anat_desc-conform_extension-['.html']_suffix-T1w">
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+
<h3 class="elem-title">Anatomical Conformation</h3>
|
| 101 |
+
<ul class="elem-desc">
|
| 102 |
+
<li>Input T1w images: 1</li>
|
| 103 |
+
<li>Output orientation: RAS</li>
|
| 104 |
+
<li>Output dimensions: 192x256x128</li>
|
| 105 |
+
<li>Output voxel size: 1mm x 1mm x 1.2mm</li>
|
| 106 |
+
<li>Discarded images: 0</li>
|
| 107 |
+
|
| 108 |
+
</ul>
|
| 109 |
+
</div>
|
| 110 |
+
<div id="datatype-anat_suffix-dseg">
|
| 111 |
+
<h3 class="run-title">Brain mask and brain tissue segmentation of the T1w</h3><p class="elem-caption">This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.</p> <img class="svg-reportlet" src="./sub-S20/figures/sub-S20_dseg.svg" style="width: 100%" />
|
| 112 |
+
</div>
|
| 113 |
+
<div class="elem-filename">
|
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+
Get figure file: <a href="./sub-S20/figures/sub-S20_dseg.svg" target="_blank">sub-S20/figures/sub-S20_dseg.svg</a>
|
| 115 |
+
</div>
|
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+
</div>
|
| 118 |
+
<div id="datatype-anat_regex_search-True_space-.*_suffix-T1w">
|
| 119 |
+
<h3 class="run-title">Spatial normalization of the anatomical T1w reference</h3><p class="elem-desc">Results of nonlinear alignment of the T1w reference one or more template space(s). Hover on the panels with the mouse pointer to transition between both spaces.</p><p class="elem-caption">Spatial normalization of the T1w image to the <code>MNI152NLin2009cAsym</code> template.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S20/figures/sub-S20_space-MNI152NLin2009cAsym_T1w.svg">
|
| 120 |
+
Problem loading figure sub-S20/figures/sub-S20_space-MNI152NLin2009cAsym_T1w.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 121 |
+
</div>
|
| 122 |
+
<div class="elem-filename">
|
| 123 |
+
Get figure file: <a href="./sub-S20/figures/sub-S20_space-MNI152NLin2009cAsym_T1w.svg" target="_blank">sub-S20/figures/sub-S20_space-MNI152NLin2009cAsym_T1w.svg</a>
|
| 124 |
+
</div>
|
| 125 |
+
|
| 126 |
+
</div>
|
| 127 |
+
</div>
|
| 128 |
+
<div id="Functional">
|
| 129 |
+
<h1 class="sub-report-title">Functional</h1>
|
| 130 |
+
<div id="datatype-func_desc-summary_suffix-bold_task-localizer">
|
| 131 |
+
<h2 class="sub-report-group">Reports for: task <span class="bids-entity">localizer</span>.</h2> <h3 class="elem-title">Summary</h3>
|
| 132 |
+
<ul class="elem-desc">
|
| 133 |
+
<li>Repetition time (TR): 2.4s</li>
|
| 134 |
+
<li>Phase-encoding (PE) direction: MISSING - Assuming Anterior-Posterior</li>
|
| 135 |
+
<li>Slice timing correction: Not applied</li>
|
| 136 |
+
<li>Susceptibility distortion correction: None</li>
|
| 137 |
+
<li>Registration: FSL <code>flirt</code> with boundary-based registration (BBR) metric - 6 dof</li>
|
| 138 |
+
<li>Confounds collected: csf, csf_derivative1, csf_derivative1_power2, csf_power2, white_matter, white_matter_derivative1, white_matter_derivative1_power2, white_matter_power2, global_signal, global_signal_derivative1, global_signal_derivative1_power2, global_signal_power2, std_dvars, dvars, framewise_displacement, t_comp_cor_00, t_comp_cor_01, t_comp_cor_02, t_comp_cor_03, a_comp_cor_00, a_comp_cor_01, a_comp_cor_02, a_comp_cor_03, a_comp_cor_04, a_comp_cor_05, a_comp_cor_06, a_comp_cor_07, a_comp_cor_08, a_comp_cor_09, a_comp_cor_10, a_comp_cor_11, a_comp_cor_12, a_comp_cor_13, a_comp_cor_14, a_comp_cor_15, a_comp_cor_16, a_comp_cor_17, a_comp_cor_18, a_comp_cor_19, a_comp_cor_20, a_comp_cor_21, a_comp_cor_22, a_comp_cor_23, a_comp_cor_24, a_comp_cor_25, a_comp_cor_26, a_comp_cor_27, a_comp_cor_28, a_comp_cor_29, a_comp_cor_30, a_comp_cor_31, a_comp_cor_32, a_comp_cor_33, a_comp_cor_34, a_comp_cor_35, a_comp_cor_36, a_comp_cor_37, a_comp_cor_38, a_comp_cor_39, a_comp_cor_40, a_comp_cor_41, a_comp_cor_42, a_comp_cor_43, a_comp_cor_44, a_comp_cor_45, a_comp_cor_46, a_comp_cor_47, a_comp_cor_48, a_comp_cor_49, a_comp_cor_50, a_comp_cor_51, a_comp_cor_52, a_comp_cor_53, a_comp_cor_54, a_comp_cor_55, a_comp_cor_56, a_comp_cor_57, a_comp_cor_58, a_comp_cor_59, a_comp_cor_60, a_comp_cor_61, a_comp_cor_62, a_comp_cor_63, a_comp_cor_64, a_comp_cor_65, a_comp_cor_66, a_comp_cor_67, a_comp_cor_68, a_comp_cor_69, a_comp_cor_70, a_comp_cor_71, a_comp_cor_72, a_comp_cor_73, a_comp_cor_74, a_comp_cor_75, a_comp_cor_76, a_comp_cor_77, a_comp_cor_78, a_comp_cor_79, a_comp_cor_80, a_comp_cor_81, a_comp_cor_82, a_comp_cor_83, a_comp_cor_84, a_comp_cor_85, a_comp_cor_86, a_comp_cor_87, a_comp_cor_88, a_comp_cor_89, a_comp_cor_90, a_comp_cor_91, a_comp_cor_92, cosine00, cosine01, cosine02, trans_x, trans_x_derivative1, trans_x_power2, trans_x_derivative1_power2, trans_y, trans_y_derivative1, trans_y_power2, trans_y_derivative1_power2, trans_z, trans_z_derivative1, trans_z_derivative1_power2, trans_z_power2, rot_x, rot_x_derivative1, rot_x_derivative1_power2, rot_x_power2, rot_y, rot_y_derivative1, rot_y_power2, rot_y_derivative1_power2, rot_z, rot_z_derivative1, rot_z_derivative1_power2, rot_z_power2</li>
|
| 139 |
+
<li>Non-steady-state volumes: 0</li>
|
| 140 |
+
</ul>
|
| 141 |
+
</div>
|
| 142 |
+
<div id="datatype-func_desc-validation_suffix-bold_task-localizer">
|
| 143 |
+
<h3 class="elem-title">Note on orientation: qform matrix overwritten</h3>
|
| 144 |
+
<p class="elem-desc">
|
| 145 |
+
The qform has been copied from sform.
|
| 146 |
+
The difference in angle is 0.
|
| 147 |
+
The difference in translation is 0.
|
| 148 |
+
</p>
|
| 149 |
+
</div>
|
| 150 |
+
<div id="datatype-func_desc-flirtbbr_suffix-bold_task-localizer">
|
| 151 |
+
<h3 class="run-title">Alignment of functional and anatomical MRI data (surface driven)</h3><p class="elem-caption">FSL <code>flirt</code> was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL <code>fast</code> (brain tissue segmentation) was used for BBR. Note that Nearest Neighbor interpolation is used in the reportlets in order to highlight potential spin-history and other artifacts, whereas final images are resampled using Lanczos interpolation.</p> <object class="svg-reportlet" type="image/svg+xml" data="./sub-S20/figures/sub-S20_task-localizer_desc-flirtbbr_bold.svg">
|
| 152 |
+
Problem loading figure sub-S20/figures/sub-S20_task-localizer_desc-flirtbbr_bold.svg. If the link below works, please try reloading the report in your browser.</object>
|
| 153 |
+
</div>
|
| 154 |
+
<div class="elem-filename">
|
| 155 |
+
Get figure file: <a href="./sub-S20/figures/sub-S20_task-localizer_desc-flirtbbr_bold.svg" target="_blank">sub-S20/figures/sub-S20_task-localizer_desc-flirtbbr_bold.svg</a>
|
| 156 |
+
</div>
|
| 157 |
+
|
| 158 |
+
</div>
|
| 159 |
+
<div id="datatype-func_desc-rois_suffix-bold_task-localizer">
|
| 160 |
+
<h3 class="run-title">Brain mask and (temporal/anatomical) CompCor ROIs</h3><p class="elem-caption">Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.<br />The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds. <br />The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.</p> <img class="svg-reportlet" src="./sub-S20/figures/sub-S20_task-localizer_desc-rois_bold.svg" style="width: 100%" />
|
| 161 |
+
</div>
|
| 162 |
+
<div class="elem-filename">
|
| 163 |
+
Get figure file: <a href="./sub-S20/figures/sub-S20_task-localizer_desc-rois_bold.svg" target="_blank">sub-S20/figures/sub-S20_task-localizer_desc-rois_bold.svg</a>
|
| 164 |
+
</div>
|
| 165 |
+
|
| 166 |
+
</div>
|
| 167 |
+
<div id="datatype-func_desc-compcorvar_suffix-bold_task-localizer">
|
| 168 |
+
<h3 class="run-title">Variance explained by t/aCompCor components</h3><p class="elem-caption">The cumulative variance explained by the first k components of the <em>t/aCompCor</em> decomposition, plotted for all values of <em>k</em>. The number of components that must be included in the model in order to explain some fraction of variance in the decomposition mask can be used as a feature selection criterion for confound regression.</p> <img class="svg-reportlet" src="./sub-S20/figures/sub-S20_task-localizer_desc-compcorvar_bold.svg" style="width: 100%" />
|
| 169 |
+
</div>
|
| 170 |
+
<div class="elem-filename">
|
| 171 |
+
Get figure file: <a href="./sub-S20/figures/sub-S20_task-localizer_desc-compcorvar_bold.svg" target="_blank">sub-S20/figures/sub-S20_task-localizer_desc-compcorvar_bold.svg</a>
|
| 172 |
+
</div>
|
| 173 |
+
|
| 174 |
+
</div>
|
| 175 |
+
<div id="datatype-func_desc-carpetplot_suffix-bold_task-localizer">
|
| 176 |
+
<h3 class="run-title">BOLD Summary</h3><p class="elem-caption">Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.<br />A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.</p> <img class="svg-reportlet" src="./sub-S20/figures/sub-S20_task-localizer_desc-carpetplot_bold.svg" style="width: 100%" />
|
| 177 |
+
</div>
|
| 178 |
+
<div class="elem-filename">
|
| 179 |
+
Get figure file: <a href="./sub-S20/figures/sub-S20_task-localizer_desc-carpetplot_bold.svg" target="_blank">sub-S20/figures/sub-S20_task-localizer_desc-carpetplot_bold.svg</a>
|
| 180 |
+
</div>
|
| 181 |
+
|
| 182 |
+
</div>
|
| 183 |
+
<div id="datatype-func_desc-confoundcorr_suffix-bold_task-localizer">
|
| 184 |
+
<h3 class="run-title">Correlations among nuisance regressors</h3><p class="elem-caption">Left: Heatmap summarizing the correlation structure among confound variables.
|
| 185 |
+
(Cosine bases and PCA-derived CompCor components are inherently orthogonal.)
|
| 186 |
+
Right: magnitude of the correlation between each confound time series and the
|
| 187 |
+
mean global signal. Strong correlations might be indicative of partial volume
|
| 188 |
+
effects and can inform decisions about feature orthogonalization prior to
|
| 189 |
+
confound regression.
|
| 190 |
+
</p> <img class="svg-reportlet" src="./sub-S20/figures/sub-S20_task-localizer_desc-confoundcorr_bold.svg" style="width: 100%" />
|
| 191 |
+
</div>
|
| 192 |
+
<div class="elem-filename">
|
| 193 |
+
Get figure file: <a href="./sub-S20/figures/sub-S20_task-localizer_desc-confoundcorr_bold.svg" target="_blank">sub-S20/figures/sub-S20_task-localizer_desc-confoundcorr_bold.svg</a>
|
| 194 |
+
</div>
|
| 195 |
+
|
| 196 |
+
</div>
|
| 197 |
+
</div>
|
| 198 |
+
<div id="About">
|
| 199 |
+
<h1 class="sub-report-title">About</h1>
|
| 200 |
+
<div id="datatype-anat_desc-about_suffix-T1w">
|
| 201 |
+
<ul>
|
| 202 |
+
<li>fMRIPrep version: 20.0.6</li>
|
| 203 |
+
<li>fMRIPrep command: <code>/usr/local/miniconda/bin/fmriprep /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/raw/ /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/preprocessed/ --fs-license-file /dartfs/rc/lab/D/DBIC/cosanlab/datax/Projects/pinel_localizer/license.txt participant --participant-label sub-S20 --nthreads 16 --omp-nthreads 16 --write-graph --fs-no-reconall --notrack</code></li>
|
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<li>Date preprocessed: 2020-05-12 16:10:02 -0400</li>
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<h1 class="sub-report-title">Methods</h1>
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<p>We kindly ask to report results preprocessed with this tool using the following
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boilerplate.</p>
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<ul class="nav nav-tabs" id="myTab" role="tablist">
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<li class="nav-item">
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<a class="nav-link active" id="HTML-tab" data-toggle="tab" href="#HTML" role="tab" aria-controls="HTML" aria-selected="true">HTML</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="Markdown-tab" data-toggle="tab" href="#Markdown" role="tab" aria-controls="Markdown" aria-selected="false">Markdown</a>
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</li>
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<li class="nav-item">
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<a class="nav-link " id="LaTeX-tab" data-toggle="tab" href="#LaTeX" role="tab" aria-controls="LaTeX" aria-selected="false">LaTeX</a>
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<div class="tab-pane fade active show" id="HTML" role="tabpanel" aria-labelledby="HTML-tab"><div class="boiler-html"><p>Results included in this manuscript come from preprocessing performed using <em>fMRIPrep</em> 20.0.6 (<span class="citation" data-cites="fmriprep1">Esteban, Markiewicz, et al. (2018)</span>; <span class="citation" data-cites="fmriprep2">Esteban, Blair, et al. (2018)</span>; RRID:SCR_016216), which is based on <em>Nipype</em> 1.4.2 (<span class="citation" data-cites="nipype1">Gorgolewski et al. (2011)</span>; <span class="citation" data-cites="nipype2">Gorgolewski et al. (2018)</span>; RRID:SCR_002502).</p>
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<dl>
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<dt>Anatomical data preprocessing</dt>
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<dd><p>The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) with <code>N4BiasFieldCorrection</code> <span class="citation" data-cites="n4">(Tustison et al. 2010)</span>, distributed with ANTs 2.2.0 <span class="citation" data-cites="ants">(Avants et al. 2008, RRID:SCR_004757)</span>, and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped with a <em>Nipype</em> implementation of the <code>antsBrainExtraction.sh</code> workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using <code>fast</code> <span class="citation" data-cites="fsl_fast">(FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001)</span>. Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through nonlinear registration with <code>antsRegistration</code> (ANTs 2.2.0), using brain-extracted versions of both T1w reference and the T1w template. The following template was selected for spatial normalization: <em>ICBM 152 Nonlinear Asymmetrical template version 2009c</em> [<span class="citation" data-cites="mni152nlin2009casym">Fonov et al. (2009)</span>, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],</p>
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</dd>
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+
<dt>Functional data preprocessing</dt>
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+
<dd><p>For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Susceptibility distortion correction (SDC) was omitted. The BOLD reference was then co-registered to the T1w reference using <code>flirt</code> <span class="citation" data-cites="flirt">(FSL 5.0.9, Jenkinson and Smith 2001)</span> with the boundary-based registration <span class="citation" data-cites="bbr">(Greve and Fischl 2009)</span> cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using <code>mcflirt</code> <span class="citation" data-cites="mcflirt">(FSL 5.0.9, Jenkinson et al. 2002)</span>. The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying the transforms to correct for head-motion. These resampled BOLD time-series will be referred to as <em>preprocessed BOLD in original space</em>, or just <em>preprocessed BOLD</em>. The BOLD time-series were resampled into standard space, generating a <em>preprocessed BOLD run in MNI152NLin2009cAsym space</em>. First, a reference volume and its skull-stripped version were generated using a custom methodology of <em>fMRIPrep</em>. Several confounding time-series were calculated based on the <em>preprocessed BOLD</em>: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in <em>Nipype</em> <span class="citation" data-cites="power_fd_dvars">(following the definitions by Power et al. 2014)</span>. The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction <span class="citation" data-cites="compcor">(<em>CompCor</em>, Behzadi et al. 2007)</span>. Principal components are estimated after high-pass filtering the <em>preprocessed BOLD</em> time-series (using a discrete cosine filter with 128s cut-off) for the two <em>CompCor</em> variants: temporal (tCompCor) and anatomical (aCompCor). tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). Components are also calculated separately within the WM and CSF masks. For each CompCor decomposition, the <em>k</em> components with the largest singular values are retained, such that the retained components’ time series are sufficient to explain 50 percent of variance across the nuisance mask (CSF, WM, combined, or temporal). The remaining components are dropped from consideration. The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. The confound time series derived from head motion estimates and global signals were expanded with the inclusion of temporal derivatives and quadratic terms for each <span class="citation" data-cites="confounds_satterthwaite_2013">(Satterthwaite et al. 2013)</span>. Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS were annotated as motion outliers. All resamplings can be performed with <em>a single interpolation step</em> by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and output spaces). Gridded (volumetric) resamplings were performed using <code>antsApplyTransforms</code> (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels <span class="citation" data-cites="lanczos">(Lanczos 1964)</span>. Non-gridded (surface) resamplings were performed using <code>mri_vol2surf</code> (FreeSurfer).</p>
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</dd>
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+
</dl>
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<p>Many internal operations of <em>fMRIPrep</em> use <em>Nilearn</em> 0.6.2 <span class="citation" data-cites="nilearn">(Abraham et al. 2014, RRID:SCR_001362)</span>, mostly within the functional processing workflow. For more details of the pipeline, see <a href="https://fmriprep.readthedocs.io/en/latest/workflows.html" title="FMRIPrep's documentation">the section corresponding to workflows in <em>fMRIPrep</em>’s documentation</a>.</p>
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<h3 id="copyright-waiver">Copyright Waiver</h3>
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<p>The above boilerplate text was automatically generated by fMRIPrep with the express intention that users should copy and paste this text into their manuscripts <em>unchanged</em>. It is released under the <a href="https://creativecommons.org/publicdomain/zero/1.0/">CC0</a> license.</p>
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<h3 id="references" class="unnumbered">References</h3>
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<div id="refs" class="references">
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<div id="ref-nilearn">
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<p>Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” <em>Frontiers in Neuroinformatics</em> 8. <a href="https://doi.org/10.3389/fninf.2014.00014" class="uri">https://doi.org/10.3389/fninf.2014.00014</a>.</p>
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</div>
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<div id="ref-ants">
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<p>Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” <em>Medical Image Analysis</em> 12 (1): 26–41. <a href="https://doi.org/10.1016/j.media.2007.06.004" class="uri">https://doi.org/10.1016/j.media.2007.06.004</a>.</p>
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</div>
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<div id="ref-compcor">
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<p>Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” <em>NeuroImage</em> 37 (1): 90–101. <a href="https://doi.org/10.1016/j.neuroimage.2007.04.042" class="uri">https://doi.org/10.1016/j.neuroimage.2007.04.042</a>.</p>
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</div>
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<div id="ref-fmriprep2">
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<p>Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.852659" class="uri">https://doi.org/10.5281/zenodo.852659</a>.</p>
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</div>
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<div id="ref-fmriprep1">
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<p>Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” <em>Nature Methods</em>. <a href="https://doi.org/10.1038/s41592-018-0235-4" class="uri">https://doi.org/10.1038/s41592-018-0235-4</a>.</p>
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</div>
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<div id="ref-mni152nlin2009casym">
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<p>Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” <em>NeuroImage</em> 47, Supplement 1: S102. <a href="https://doi.org/10.1016/S1053-8119(09)70884-5" class="uri">https://doi.org/10.1016/S1053-8119(09)70884-5</a>.</p>
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</div>
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<div id="ref-nipype1">
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<p>Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” <em>Frontiers in Neuroinformatics</em> 5: 13. <a href="https://doi.org/10.3389/fninf.2011.00013" class="uri">https://doi.org/10.3389/fninf.2011.00013</a>.</p>
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</div>
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<div id="ref-nipype2">
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<p>Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” <em>Software</em>. Zenodo. <a href="https://doi.org/10.5281/zenodo.596855" class="uri">https://doi.org/10.5281/zenodo.596855</a>.</p>
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</div>
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<div id="ref-bbr">
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<p>Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” <em>NeuroImage</em> 48 (1): 63–72. <a href="https://doi.org/10.1016/j.neuroimage.2009.06.060" class="uri">https://doi.org/10.1016/j.neuroimage.2009.06.060</a>.</p>
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</div>
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<div id="ref-mcflirt">
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<p>Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” <em>NeuroImage</em> 17 (2): 825–41. <a href="https://doi.org/10.1006/nimg.2002.1132" class="uri">https://doi.org/10.1006/nimg.2002.1132</a>.</p>
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</div>
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<div id="ref-flirt">
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<p>Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” <em>Medical Image Analysis</em> 5 (2): 143–56. <a href="https://doi.org/10.1016/S1361-8415(01)00036-6" class="uri">https://doi.org/10.1016/S1361-8415(01)00036-6</a>.</p>
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</div>
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<div id="ref-lanczos">
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<p>Lanczos, C. 1964. “Evaluation of Noisy Data.” <em>Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis</em> 1 (1): 76–85. <a href="https://doi.org/10.1137/0701007" class="uri">https://doi.org/10.1137/0701007</a>.</p>
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</div>
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<div id="ref-power_fd_dvars">
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<p>Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” <em>NeuroImage</em> 84 (Supplement C): 320–41. <a href="https://doi.org/10.1016/j.neuroimage.2013.08.048" class="uri">https://doi.org/10.1016/j.neuroimage.2013.08.048</a>.</p>
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</div>
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<div id="ref-confounds_satterthwaite_2013">
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<p>Satterthwaite, Theodore D., Mark A. Elliott, Raphael T. Gerraty, Kosha Ruparel, James Loughead, Monica E. Calkins, Simon B. Eickhoff, et al. 2013. “An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data.” <em>NeuroImage</em> 64 (1): 240–56. <a href="https://doi.org/10.1016/j.neuroimage.2012.08.052" class="uri">https://doi.org/10.1016/j.neuroimage.2012.08.052</a>.</p>
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</div>
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<div id="ref-n4">
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<p>Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” <em>IEEE Transactions on Medical Imaging</em> 29 (6): 1310–20. <a href="https://doi.org/10.1109/TMI.2010.2046908" class="uri">https://doi.org/10.1109/TMI.2010.2046908</a>.</p>
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</div>
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<div id="ref-fsl_fast">
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<p>Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” <em>IEEE Transactions on Medical Imaging</em> 20 (1): 45–57. <a href="https://doi.org/10.1109/42.906424" class="uri">https://doi.org/10.1109/42.906424</a>.</p>
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</div></div></div>
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<div class="tab-pane fade " id="Markdown" role="tabpanel" aria-labelledby="Markdown-tab"><pre>
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+
Results included in this manuscript come from preprocessing
|
| 291 |
+
performed using *fMRIPrep* 20.0.6
|
| 292 |
+
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
|
| 293 |
+
which is based on *Nipype* 1.4.2
|
| 294 |
+
(@nipype1; @nipype2; RRID:SCR_002502).
|
| 295 |
+
|
| 296 |
+
Anatomical data preprocessing
|
| 297 |
+
|
| 298 |
+
: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
|
| 299 |
+
with `N4BiasFieldCorrection` [@n4], distributed with ANTs 2.2.0 [@ants, RRID:SCR_004757], and used as T1w-reference throughout the workflow.
|
| 300 |
+
The T1w-reference was then skull-stripped with a *Nipype* implementation of
|
| 301 |
+
the `antsBrainExtraction.sh` workflow (from ANTs), using OASIS30ANTs
|
| 302 |
+
as target template.
|
| 303 |
+
Brain tissue segmentation of cerebrospinal fluid (CSF),
|
| 304 |
+
white-matter (WM) and gray-matter (GM) was performed on
|
| 305 |
+
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
|
| 306 |
+
@fsl_fast].
|
| 307 |
+
Volume-based spatial normalization to one standard space (MNI152NLin2009cAsym) was performed through
|
| 308 |
+
nonlinear registration with `antsRegistration` (ANTs 2.2.0),
|
| 309 |
+
using brain-extracted versions of both T1w reference and the T1w template.
|
| 310 |
+
The following template was selected for spatial normalization:
|
| 311 |
+
*ICBM 152 Nonlinear Asymmetrical template version 2009c* [@mni152nlin2009casym, RRID:SCR_008796; TemplateFlow ID: MNI152NLin2009cAsym],
|
| 312 |
+
|
| 313 |
+
Functional data preprocessing
|
| 314 |
+
|
| 315 |
+
: For each of the 1 BOLD runs found per subject (across all
|
| 316 |
+
tasks and sessions), the following preprocessing was performed.
|
| 317 |
+
First, a reference volume and its skull-stripped version were generated
|
| 318 |
+
using a custom methodology of *fMRIPrep*.
|
| 319 |
+
Susceptibility distortion correction (SDC) was omitted.
|
| 320 |
+
The BOLD reference was then co-registered to the T1w reference using
|
| 321 |
+
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
|
| 322 |
+
cost-function.
|
| 323 |
+
Co-registration was configured with nine degrees of freedom to account
|
| 324 |
+
for distortions remaining in the BOLD reference.
|
| 325 |
+
Head-motion parameters with respect to the BOLD reference
|
| 326 |
+
(transformation matrices, and six corresponding rotation and translation
|
| 327 |
+
parameters) are estimated before any spatiotemporal filtering using
|
| 328 |
+
`mcflirt` [FSL 5.0.9, @mcflirt].
|
| 329 |
+
The BOLD time-series (including slice-timing correction when applied)
|
| 330 |
+
were resampled onto their original, native space by applying
|
| 331 |
+
the transforms to correct for head-motion.
|
| 332 |
+
These resampled BOLD time-series will be referred to as *preprocessed
|
| 333 |
+
BOLD in original space*, or just *preprocessed BOLD*.
|
| 334 |
+
The BOLD time-series were resampled into standard space,
|
| 335 |
+
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
|
| 336 |
+
First, a reference volume and its skull-stripped version were generated
|
| 337 |
+
using a custom methodology of *fMRIPrep*.
|
| 338 |
+
Several confounding time-series were calculated based on the
|
| 339 |
+
*preprocessed BOLD*: framewise displacement (FD), DVARS and
|
| 340 |
+
three region-wise global signals.
|
| 341 |
+
FD and DVARS are calculated for each functional run, both using their
|
| 342 |
+
implementations in *Nipype* [following the definitions by @power_fd_dvars].
|
| 343 |
+
The three global signals are extracted within the CSF, the WM, and
|
| 344 |
+
the whole-brain masks.
|
| 345 |
+
Additionally, a set of physiological regressors were extracted to
|
| 346 |
+
allow for component-based noise correction [*CompCor*, @compcor].
|
| 347 |
+
Principal components are estimated after high-pass filtering the
|
| 348 |
+
*preprocessed BOLD* time-series (using a discrete cosine filter with
|
| 349 |
+
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
|
| 350 |
+
and anatomical (aCompCor).
|
| 351 |
+
tCompCor components are then calculated from the top 5% variable
|
| 352 |
+
voxels within a mask covering the subcortical regions.
|
| 353 |
+
This subcortical mask is obtained by heavily eroding the brain mask,
|
| 354 |
+
which ensures it does not include cortical GM regions.
|
| 355 |
+
For aCompCor, components are calculated within the intersection of
|
| 356 |
+
the aforementioned mask and the union of CSF and WM masks calculated
|
| 357 |
+
in T1w space, after their projection to the native space of each
|
| 358 |
+
functional run (using the inverse BOLD-to-T1w transformation). Components
|
| 359 |
+
are also calculated separately within the WM and CSF masks.
|
| 360 |
+
For each CompCor decomposition, the *k* components with the largest singular
|
| 361 |
+
values are retained, such that the retained components' time series are
|
| 362 |
+
sufficient to explain 50 percent of variance across the nuisance mask (CSF,
|
| 363 |
+
WM, combined, or temporal). The remaining components are dropped from
|
| 364 |
+
consideration.
|
| 365 |
+
The head-motion estimates calculated in the correction step were also
|
| 366 |
+
placed within the corresponding confounds file.
|
| 367 |
+
The confound time series derived from head motion estimates and global
|
| 368 |
+
signals were expanded with the inclusion of temporal derivatives and
|
| 369 |
+
quadratic terms for each [@confounds_satterthwaite_2013].
|
| 370 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 371 |
+
were annotated as motion outliers.
|
| 372 |
+
All resamplings can be performed with *a single interpolation
|
| 373 |
+
step* by composing all the pertinent transformations (i.e. head-motion
|
| 374 |
+
transform matrices, susceptibility distortion correction when available,
|
| 375 |
+
and co-registrations to anatomical and output spaces).
|
| 376 |
+
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
|
| 377 |
+
configured with Lanczos interpolation to minimize the smoothing
|
| 378 |
+
effects of other kernels [@lanczos].
|
| 379 |
+
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
|
| 380 |
+
(FreeSurfer).
|
| 381 |
+
|
| 382 |
+
|
| 383 |
+
Many internal operations of *fMRIPrep* use
|
| 384 |
+
*Nilearn* 0.6.2 [@nilearn, RRID:SCR_001362],
|
| 385 |
+
mostly within the functional processing workflow.
|
| 386 |
+
For more details of the pipeline, see [the section corresponding
|
| 387 |
+
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").
|
| 388 |
+
|
| 389 |
+
|
| 390 |
+
### Copyright Waiver
|
| 391 |
+
|
| 392 |
+
The above boilerplate text was automatically generated by fMRIPrep
|
| 393 |
+
with the express intention that users should copy and paste this
|
| 394 |
+
text into their manuscripts *unchanged*.
|
| 395 |
+
It is released under the [CC0](https://creativecommons.org/publicdomain/zero/1.0/) license.
|
| 396 |
+
|
| 397 |
+
### References
|
| 398 |
+
|
| 399 |
+
</pre>
|
| 400 |
+
</div>
|
| 401 |
+
<div class="tab-pane fade " id="LaTeX" role="tabpanel" aria-labelledby="LaTeX-tab"><pre>Results included in this manuscript come from preprocessing performed
|
| 402 |
+
using \emph{fMRIPrep} 20.0.6 (\citet{fmriprep1}; \citet{fmriprep2};
|
| 403 |
+
RRID:SCR\_016216), which is based on \emph{Nipype} 1.4.2
|
| 404 |
+
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).
|
| 405 |
+
|
| 406 |
+
\begin{description}
|
| 407 |
+
\item[Anatomical data preprocessing]
|
| 408 |
+
The T1-weighted (T1w) image was corrected for intensity non-uniformity
|
| 409 |
+
(INU) with \texttt{N4BiasFieldCorrection} \citep{n4}, distributed with
|
| 410 |
+
ANTs 2.2.0 \citep[RRID:SCR\_004757]{ants}, and used as T1w-reference
|
| 411 |
+
throughout the workflow. The T1w-reference was then skull-stripped with
|
| 412 |
+
a \emph{Nipype} implementation of the \texttt{antsBrainExtraction.sh}
|
| 413 |
+
workflow (from ANTs), using OASIS30ANTs as target template. Brain tissue
|
| 414 |
+
segmentation of cerebrospinal fluid (CSF), white-matter (WM) and
|
| 415 |
+
gray-matter (GM) was performed on the brain-extracted T1w using
|
| 416 |
+
\texttt{fast} \citep[FSL 5.0.9, RRID:SCR\_002823,][]{fsl_fast}.
|
| 417 |
+
Volume-based spatial normalization to one standard space
|
| 418 |
+
(MNI152NLin2009cAsym) was performed through nonlinear registration with
|
| 419 |
+
\texttt{antsRegistration} (ANTs 2.2.0), using brain-extracted versions
|
| 420 |
+
of both T1w reference and the T1w template. The following template was
|
| 421 |
+
selected for spatial normalization: \emph{ICBM 152 Nonlinear
|
| 422 |
+
Asymmetrical template version 2009c} {[}\citet{mni152nlin2009casym},
|
| 423 |
+
RRID:SCR\_008796; TemplateFlow ID: MNI152NLin2009cAsym{]},
|
| 424 |
+
\item[Functional data preprocessing]
|
| 425 |
+
For each of the 1 BOLD runs found per subject (across all tasks and
|
| 426 |
+
sessions), the following preprocessing was performed. First, a reference
|
| 427 |
+
volume and its skull-stripped version were generated using a custom
|
| 428 |
+
methodology of \emph{fMRIPrep}. Susceptibility distortion correction
|
| 429 |
+
(SDC) was omitted. The BOLD reference was then co-registered to the T1w
|
| 430 |
+
reference using \texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the
|
| 431 |
+
boundary-based registration \citep{bbr} cost-function. Co-registration
|
| 432 |
+
was configured with nine degrees of freedom to account for distortions
|
| 433 |
+
remaining in the BOLD reference. Head-motion parameters with respect to
|
| 434 |
+
the BOLD reference (transformation matrices, and six corresponding
|
| 435 |
+
rotation and translation parameters) are estimated before any
|
| 436 |
+
spatiotemporal filtering using \texttt{mcflirt} \citep[FSL
|
| 437 |
+
5.0.9,][]{mcflirt}. The BOLD time-series (including slice-timing
|
| 438 |
+
correction when applied) were resampled onto their original, native
|
| 439 |
+
space by applying the transforms to correct for head-motion. These
|
| 440 |
+
resampled BOLD time-series will be referred to as \emph{preprocessed
|
| 441 |
+
BOLD in original space}, or just \emph{preprocessed BOLD}. The BOLD
|
| 442 |
+
time-series were resampled into standard space, generating a
|
| 443 |
+
\emph{preprocessed BOLD run in MNI152NLin2009cAsym space}. First, a
|
| 444 |
+
reference volume and its skull-stripped version were generated using a
|
| 445 |
+
custom methodology of \emph{fMRIPrep}. Several confounding time-series
|
| 446 |
+
were calculated based on the \emph{preprocessed BOLD}: framewise
|
| 447 |
+
displacement (FD), DVARS and three region-wise global signals. FD and
|
| 448 |
+
DVARS are calculated for each functional run, both using their
|
| 449 |
+
implementations in \emph{Nipype} \citep[following the definitions
|
| 450 |
+
by][]{power_fd_dvars}. The three global signals are extracted within the
|
| 451 |
+
CSF, the WM, and the whole-brain masks. Additionally, a set of
|
| 452 |
+
physiological regressors were extracted to allow for component-based
|
| 453 |
+
noise correction \citep[\emph{CompCor},][]{compcor}. Principal
|
| 454 |
+
components are estimated after high-pass filtering the
|
| 455 |
+
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
|
| 456 |
+
with 128s cut-off) for the two \emph{CompCor} variants: temporal
|
| 457 |
+
(tCompCor) and anatomical (aCompCor). tCompCor components are then
|
| 458 |
+
calculated from the top 5\% variable voxels within a mask covering the
|
| 459 |
+
subcortical regions. This subcortical mask is obtained by heavily
|
| 460 |
+
eroding the brain mask, which ensures it does not include cortical GM
|
| 461 |
+
regions. For aCompCor, components are calculated within the intersection
|
| 462 |
+
of the aforementioned mask and the union of CSF and WM masks calculated
|
| 463 |
+
in T1w space, after their projection to the native space of each
|
| 464 |
+
functional run (using the inverse BOLD-to-T1w transformation).
|
| 465 |
+
Components are also calculated separately within the WM and CSF masks.
|
| 466 |
+
For each CompCor decomposition, the \emph{k} components with the largest
|
| 467 |
+
singular values are retained, such that the retained components' time
|
| 468 |
+
series are sufficient to explain 50 percent of variance across the
|
| 469 |
+
nuisance mask (CSF, WM, combined, or temporal). The remaining components
|
| 470 |
+
are dropped from consideration. The head-motion estimates calculated in
|
| 471 |
+
the correction step were also placed within the corresponding confounds
|
| 472 |
+
file. The confound time series derived from head motion estimates and
|
| 473 |
+
global signals were expanded with the inclusion of temporal derivatives
|
| 474 |
+
and quadratic terms for each \citep{confounds_satterthwaite_2013}.
|
| 475 |
+
Frames that exceeded a threshold of 0.5 mm FD or 1.5 standardised DVARS
|
| 476 |
+
were annotated as motion outliers. All resamplings can be performed with
|
| 477 |
+
\emph{a single interpolation step} by composing all the pertinent
|
| 478 |
+
transformations (i.e.~head-motion transform matrices, susceptibility
|
| 479 |
+
distortion correction when available, and co-registrations to anatomical
|
| 480 |
+
and output spaces). Gridded (volumetric) resamplings were performed
|
| 481 |
+
using \texttt{antsApplyTransforms} (ANTs), configured with Lanczos
|
| 482 |
+
interpolation to minimize the smoothing effects of other kernels
|
| 483 |
+
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
|
| 484 |
+
\texttt{mri\_vol2surf} (FreeSurfer).
|
| 485 |
+
\end{description}
|
| 486 |
+
|
| 487 |
+
Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.6.2
|
| 488 |
+
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
|
| 489 |
+
processing workflow. For more details of the pipeline, see
|
| 490 |
+
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
|
| 491 |
+
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.
|
| 492 |
+
|
| 493 |
+
\hypertarget{copyright-waiver}{%
|
| 494 |
+
\subsubsection{Copyright Waiver}\label{copyright-waiver}}
|
| 495 |
+
|
| 496 |
+
The above boilerplate text was automatically generated by fMRIPrep with
|
| 497 |
+
the express intention that users should copy and paste this text into
|
| 498 |
+
their manuscripts \emph{unchanged}. It is released under the
|
| 499 |
+
\href{https://creativecommons.org/publicdomain/zero/1.0/}{CC0} license.
|
| 500 |
+
|
| 501 |
+
\hypertarget{references}{%
|
| 502 |
+
\subsubsection{References}\label{references}}
|
| 503 |
+
|
| 504 |
+
\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}</pre>
|
| 505 |
+
<h3>Bibliography</h3>
|
| 506 |
+
<pre>@article{fmriprep1,
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| 507 |
+
author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
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author = {Wang, Sijia and Peterson, Daniel J. and Gatenby, J. C. and Li, Wenbin and Grabowski, Thomas J. and Madhyastha, Tara M.},
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language = {English},
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title = {Evaluation of Field Map and Nonlinear Registration Methods for Correction of Susceptibility Artifacts in Diffusion {MRI}},
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|
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}
|
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@phdthesis{fieldmapless2,
|
| 659 |
+
address = {Berlin},
|
| 660 |
+
author = {Huntenburg, Julia M.},
|
| 661 |
+
language = {eng},
|
| 662 |
+
school = {Freie Universität},
|
| 663 |
+
title = {Evaluating nonlinear coregistration of {BOLD} {EPI} and T1w images},
|
| 664 |
+
type = {Master's Thesis},
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+
url = {http://hdl.handle.net/11858/00-001M-0000-002B-1CB5-A},
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| 666 |
+
year = 2014
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| 667 |
+
}
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| 671 |
+
doi = {10.1371/journal.pone.0152472},
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| 672 |
+
issn = {1932-6203},
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| 673 |
+
journal = {PLOS ONE},
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| 674 |
+
number = 3,
|
| 675 |
+
pages = {e0152472},
|
| 676 |
+
title = {Characterization and Correction of Geometric Distortions in 814 Diffusion Weighted Images},
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| 677 |
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+
year = 2016
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@article{flirt,
|
| 683 |
+
title = {A global optimisation method for robust affine registration of brain images},
|
| 684 |
+
volume = {5},
|
| 685 |
+
issn = {1361-8415},
|
| 686 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1361841501000366},
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| 687 |
+
doi = {10.1016/S1361-8415(01)00036-6},
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| 688 |
+
number = {2},
|
| 689 |
+
urldate = {2018-07-27},
|
| 690 |
+
journal = {Medical Image Analysis},
|
| 691 |
+
author = {Jenkinson, Mark and Smith, Stephen},
|
| 692 |
+
year = {2001},
|
| 693 |
+
keywords = {Affine transformation, flirt, fsl, Global optimisation, Multi-resolution search, Multimodal registration, Robustness},
|
| 694 |
+
pages = {143--156}
|
| 695 |
+
}
|
| 696 |
+
|
| 697 |
+
@article{mcflirt,
|
| 698 |
+
author = {Jenkinson, Mark and Bannister, Peter and Brady, Michael and Smith, Stephen},
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| 699 |
+
doi = {10.1006/nimg.2002.1132},
|
| 700 |
+
issn = {1053-8119},
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| 701 |
+
journal = {NeuroImage},
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| 702 |
+
number = 2,
|
| 703 |
+
pages = {825-841},
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| 704 |
+
title = {Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images},
|
| 705 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811902911328},
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| 706 |
+
volume = 17,
|
| 707 |
+
year = 2002
|
| 708 |
+
}
|
| 709 |
+
|
| 710 |
+
@article{bbr,
|
| 711 |
+
author = {Greve, Douglas N and Fischl, Bruce},
|
| 712 |
+
doi = {10.1016/j.neuroimage.2009.06.060},
|
| 713 |
+
issn = {1095-9572},
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| 714 |
+
journal = {NeuroImage},
|
| 715 |
+
number = 1,
|
| 716 |
+
pages = {63-72},
|
| 717 |
+
title = {Accurate and robust brain image alignment using boundary-based registration},
|
| 718 |
+
volume = 48,
|
| 719 |
+
year = 2009
|
| 720 |
+
}
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| 721 |
+
|
| 722 |
+
@article{aroma,
|
| 723 |
+
author = {Pruim, Raimon H. R. and Mennes, Maarten and van Rooij, Daan and Llera, Alberto and Buitelaar, Jan K. and Beckmann, Christian F.},
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| 724 |
+
doi = {10.1016/j.neuroimage.2015.02.064},
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| 725 |
+
issn = {1053-8119},
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| 726 |
+
journal = {NeuroImage},
|
| 727 |
+
number = {Supplement C},
|
| 728 |
+
pages = {267-277},
|
| 729 |
+
shorttitle = {ICA-AROMA},
|
| 730 |
+
title = {ICA-{AROMA}: A robust {ICA}-based strategy for removing motion artifacts from fMRI data},
|
| 731 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811915001822},
|
| 732 |
+
volume = 112,
|
| 733 |
+
year = 2015
|
| 734 |
+
}
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| 735 |
+
|
| 736 |
+
@article{power_fd_dvars,
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| 737 |
+
author = {Power, Jonathan D. and Mitra, Anish and Laumann, Timothy O. and Snyder, Abraham Z. and Schlaggar, Bradley L. and Petersen, Steven E.},
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| 738 |
+
doi = {10.1016/j.neuroimage.2013.08.048},
|
| 739 |
+
issn = {1053-8119},
|
| 740 |
+
journal = {NeuroImage},
|
| 741 |
+
number = {Supplement C},
|
| 742 |
+
pages = {320-341},
|
| 743 |
+
title = {Methods to detect, characterize, and remove motion artifact in resting state fMRI},
|
| 744 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913009117},
|
| 745 |
+
volume = 84,
|
| 746 |
+
year = 2014
|
| 747 |
+
}
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| 748 |
+
|
| 749 |
+
@article{confounds_satterthwaite_2013,
|
| 750 |
+
author = {Satterthwaite, Theodore D. and Elliott, Mark A. and Gerraty, Raphael T. and Ruparel, Kosha and Loughead, James and Calkins, Monica E. and Eickhoff, Simon B. and Hakonarson, Hakon and Gur, Ruben C. and Gur, Raquel E. and Wolf, Daniel H.},
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| 751 |
+
doi = {10.1016/j.neuroimage.2012.08.052},
|
| 752 |
+
issn = {10538119},
|
| 753 |
+
journal = {NeuroImage},
|
| 754 |
+
number = 1,
|
| 755 |
+
pages = {240--256},
|
| 756 |
+
title = {{An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data}},
|
| 757 |
+
url = {http://linkinghub.elsevier.com/retrieve/pii/S1053811912008609},
|
| 758 |
+
volume = 64,
|
| 759 |
+
year = 2013
|
| 760 |
+
}
|
| 761 |
+
|
| 762 |
+
|
| 763 |
+
@article{nilearn,
|
| 764 |
+
author = {Abraham, Alexandre and Pedregosa, Fabian and Eickenberg, Michael and Gervais, Philippe and Mueller, Andreas and Kossaifi, Jean and Gramfort, Alexandre and Thirion, Bertrand and Varoquaux, Gael},
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| 765 |
+
doi = {10.3389/fninf.2014.00014},
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| 766 |
+
issn = {1662-5196},
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| 767 |
+
journal = {Frontiers in Neuroinformatics},
|
| 768 |
+
language = {English},
|
| 769 |
+
title = {Machine learning for neuroimaging with scikit-learn},
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| 770 |
+
url = {https://www.frontiersin.org/articles/10.3389/fninf.2014.00014/full},
|
| 771 |
+
volume = 8,
|
| 772 |
+
year = 2014
|
| 773 |
+
}
|
| 774 |
+
|
| 775 |
+
@article{lanczos,
|
| 776 |
+
author = {Lanczos, C.},
|
| 777 |
+
doi = {10.1137/0701007},
|
| 778 |
+
issn = {0887-459X},
|
| 779 |
+
journal = {Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis},
|
| 780 |
+
number = 1,
|
| 781 |
+
pages = {76-85},
|
| 782 |
+
title = {Evaluation of Noisy Data},
|
| 783 |
+
url = {http://epubs.siam.org/doi/10.1137/0701007},
|
| 784 |
+
volume = 1,
|
| 785 |
+
year = 1964
|
| 786 |
+
}
|
| 787 |
+
|
| 788 |
+
@article{compcor,
|
| 789 |
+
author = {Behzadi, Yashar and Restom, Khaled and Liau, Joy and Liu, Thomas T.},
|
| 790 |
+
doi = {10.1016/j.neuroimage.2007.04.042},
|
| 791 |
+
issn = {1053-8119},
|
| 792 |
+
journal = {NeuroImage},
|
| 793 |
+
number = 1,
|
| 794 |
+
pages = {90-101},
|
| 795 |
+
title = {A component based noise correction method ({CompCor}) for {BOLD} and perfusion based fMRI},
|
| 796 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811907003837},
|
| 797 |
+
volume = 37,
|
| 798 |
+
year = 2007
|
| 799 |
+
}
|
| 800 |
+
|
| 801 |
+
@article{hcppipelines,
|
| 802 |
+
author = {Glasser, Matthew F. and Sotiropoulos, Stamatios N. and Wilson, J. Anthony and Coalson, Timothy S. and Fischl, Bruce and Andersson, Jesper L. and Xu, Junqian and Jbabdi, Saad and Webster, Matthew and Polimeni, Jonathan R. and Van Essen, David C. and Jenkinson, Mark},
|
| 803 |
+
doi = {10.1016/j.neuroimage.2013.04.127},
|
| 804 |
+
issn = {1053-8119},
|
| 805 |
+
journal = {NeuroImage},
|
| 806 |
+
pages = {105-124},
|
| 807 |
+
series = {Mapping the Connectome},
|
| 808 |
+
title = {The minimal preprocessing pipelines for the Human Connectome Project},
|
| 809 |
+
url = {http://www.sciencedirect.com/science/article/pii/S1053811913005053},
|
| 810 |
+
volume = 80,
|
| 811 |
+
year = 2013
|
| 812 |
+
}
|
| 813 |
+
|
| 814 |
+
@article{fs_template,
|
| 815 |
+
author = {Reuter, Martin and Rosas, Herminia Diana and Fischl, Bruce},
|
| 816 |
+
doi = {10.1016/j.neuroimage.2010.07.020},
|
| 817 |
+
journal = {NeuroImage},
|
| 818 |
+
number = 4,
|
| 819 |
+
pages = {1181-1196},
|
| 820 |
+
title = {Highly accurate inverse consistent registration: A robust approach},
|
| 821 |
+
volume = 53,
|
| 822 |
+
year = 2010
|
| 823 |
+
}
|
| 824 |
+
|
| 825 |
+
@article{afni,
|
| 826 |
+
author = {Cox, Robert W. and Hyde, James S.},
|
| 827 |
+
doi = {10.1002/(SICI)1099-1492(199706/08)10:4/5<171::AID-NBM453>3.0.CO;2-L},
|
| 828 |
+
journal = {NMR in Biomedicine},
|
| 829 |
+
number = {4-5},
|
| 830 |
+
pages = {171-178},
|
| 831 |
+
title = {Software tools for analysis and visualization of fMRI data},
|
| 832 |
+
volume = 10,
|
| 833 |
+
year = 1997
|
| 834 |
+
}
|
| 835 |
+
|
| 836 |
+
@article{posse_t2s,
|
| 837 |
+
author = {Posse, Stefan and Wiese, Stefan and Gembris, Daniel and Mathiak, Klaus and Kessler, Christoph and Grosse-Ruyken, Maria-Liisa and Elghahwagi, Barbara and Richards, Todd and Dager, Stephen R. and Kiselev, Valerij G.},
|
| 838 |
+
doi = {10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O},
|
| 839 |
+
journal = {Magnetic Resonance in Medicine},
|
| 840 |
+
number = 1,
|
| 841 |
+
pages = {87-97},
|
| 842 |
+
title = {Enhancement of {BOLD}-contrast sensitivity by single-shot multi-echo functional {MR} imaging},
|
| 843 |
+
volume = 42,
|
| 844 |
+
year = 1999
|
| 845 |
+
}
|
| 846 |
+
</pre>
|
| 847 |
+
</div>
|
| 848 |
+
</div>
|
| 849 |
+
</div>
|
| 850 |
+
|
| 851 |
+
<div id="errors">
|
| 852 |
+
<h1 class="sub-report-title">Errors</h1>
|
| 853 |
+
<p>No errors to report!</p>
|
| 854 |
+
</div>
|
| 855 |
+
|
| 856 |
+
|
| 857 |
+
<script type="text/javascript">
|
| 858 |
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function toggle(id) {
|
| 859 |
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var element = document.getElementById(id);
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| 860 |
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if(element.style.display == 'block')
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| 861 |
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|
| 863 |
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|
| 865 |
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|
| 866 |
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|
| 867 |
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participants.json
ADDED
|
@@ -0,0 +1,22 @@
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|
|
|
|
| 1 |
+
{
|
| 2 |
+
"age": {
|
| 3 |
+
"Description": "Age of the participant",
|
| 4 |
+
"Units": "years"
|
| 5 |
+
},
|
| 6 |
+
"sex": {
|
| 7 |
+
"Description": "Biological sex of the participant",
|
| 8 |
+
"Levels": {
|
| 9 |
+
"M": "male",
|
| 10 |
+
"F": "female"
|
| 11 |
+
}
|
| 12 |
+
},
|
| 13 |
+
"site": {
|
| 14 |
+
"Description": "Assessment site"
|
| 15 |
+
},
|
| 16 |
+
"family": {
|
| 17 |
+
"Description": "Identifier of the participant's family"
|
| 18 |
+
},
|
| 19 |
+
"language": {
|
| 20 |
+
"Description": "Participant's mother-tongue"
|
| 21 |
+
}
|
| 22 |
+
}
|
participants.tsv
ADDED
|
@@ -0,0 +1,21 @@
|
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|
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|
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|
|
|
|
|
|
|
|
| 1 |
+
participant_id age sex site family language
|
| 2 |
+
S01 24 M SHFJ F01 French
|
| 3 |
+
S02 20 M SHFJ F02 French
|
| 4 |
+
S03 22 F SHFJ F03 French
|
| 5 |
+
S04 20 M Neurospin F04 French
|
| 6 |
+
S05 23 F Neurospin F05 French
|
| 7 |
+
S06 19 M Neurospin F06 French
|
| 8 |
+
S07 26 F Neurospin F07 French
|
| 9 |
+
S08 27 M Neurospin F89 French
|
| 10 |
+
S09 21 F Neurospin F09 French
|
| 11 |
+
S10 24 F SHFJ F10 French
|
| 12 |
+
S11 47 F SHFJ F11 French
|
| 13 |
+
S12 23 F SHFJ F12 French
|
| 14 |
+
S13 19 M Neurospin F13 French
|
| 15 |
+
S14 21 F SHFJ F14 French
|
| 16 |
+
S15 22 F SHFJ F15 French
|
| 17 |
+
S16 24 F SHFJ F16 French
|
| 18 |
+
S17 22 M SHFJ F17 French
|
| 19 |
+
S18 20 F Neurospin F18 French
|
| 20 |
+
S19 18 M SHFJ F52 French
|
| 21 |
+
S20 25 F SHFJ F20 French
|
phenotype/behavioural.tsv
ADDED
|
@@ -0,0 +1,95 @@
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|
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|
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|
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|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
participant_id nuage2 pente_dots_lin couleur nom_des_gens pb_phono lin_vs_log aspect pb_express facilite_addition espece_plante visu_vb_pour_calcul tv r2_dots_log ratio_pw_w pb_allocentrique pb_rotation details score_cal_complexe activites_pratiques_nb bruxe espece_animales mot pb_lecture moyenne_pw_w trajet score_3d nuage10 nuage11 nuage12 pb_ecriture gaucherie score_addition probleme_ecole facilite_soustraction pente_dots_log arc perspective score_multiplication r2_dots_lin pair1 pair3 pair2 pair5 pair4 itineraire_plan score_soustraction erreur_w imagerie type_pb_langage decomposition niveau_etude francais1erl geometrie coef_bisec pente_sujet_estim_lin pb_prononc seine parle_tard pb_a_l_ecole autoestimation_calcul lettre_miroir rapport_pente_lin_groupe comment nuage3 nuage1 nuage6 nuage7 nuage4 nuage5 strategie nuage8 nuage9 score_tableau_langage pb_binaire erreur_langage droitier erreur_ps_w pb_consonne facilite_multiplication dyslexie visage coef_estim_qt pb_nonlangage bilingue dessin_fini bus billet pente_sujet_estim_log autoevaluation_cx pb_reconnaissance difference_pw_w score_pb_g_d car synaesthete error difficult_apprend_lire pente_bisec orthophoniste lieux orientation normalized_pw autoevaluation_dessin bonne_reconnaissance lycee avion id difficulte_calc_localizer dessin_note_sur_20 rapport_pente_log_groupe score_imageur visuel_verbal algebre pain edimburgh arbre g_contrarie lecture_ok pb_en_3d pb_2eme_langue oiseau pb_egocentrique pseudo pente_estim_qt autoevaluation_rotation pb_orthogr
|
| 2 |
+
S01 35.0 0.416922 n/a n/a False -0.0952051 4.0 False 4.0 n/a 1.0 17.0 0.916693 1.875 False False 2.0 0.966667 n/a 500.0 n/a 8.0 False 11.5 9.0 0.916667 20.0 10.0 35.0 False 0.0 10.0 0.0 4.0 0.749906 40.0 2.0 10.0 0.821488 3.0 23.0 5.0 68.0 43.0 n/a 10.0 1.0 3.0 0 False 4.0 True 4.0 0.985224 0.642131 False 60.0 False False 3.0 False 0.620551 n/a 10.0 25.0 20.0 40.0 50.0 65.0 u 15.0 30.0 4.0 False 0.0 True 3.0 False 4.0 False 1.0 0.969218 False False 1.0 17.0 13.0 0.862849 4.0 0 7.0 0.0 53.0 0 n/a False 0.953448 False 2.0 4.0 0.304348 2.0 lieux 4.0 70.0 165 n/a 18.0 0.85468 9.51389 4.0 4.0 60.0 10.0 30.0 False True False False 2.4 False 15.0 0.988097 4.0 False
|
| 3 |
+
S02 30.0 0.529093 n/a n/a False 0.0151144 3.5 False 3.0 n/a 3.0 20.0 0.954898 1.77778 False False 1.0 0.933333 3.4 700.0 n/a 9.0 False 12.5 5.0 0.916667 30.0 10.0 40.0 False 0.0 10.0 0.0 4.0 0.76985 20.0 2.0 10.0 0.970012 3.0 29.0 4.0 65.0 43.0 n/a 8.0 0.0 3.0 0 True 3.0 True 3.0 0.999742 0.776734 False 50.0 False False 3.0 False 0.787507 n/a 15.0 25.0 20.0 50.0 55.0 70.0 n/a 20.0 60.0 2.5 False 0.0 True 2.0 False 5.0 False 1.0 0.90535 False False 1.0 8.0 10.0 0.873827 3.0 0 7.0 0.0 52.0 n/a n/a False 1.00269 False 1.0 3.0 0.28 1.0 0 3.0 20.0 174 n/a 15.0 0.87741 7.80556 8.0 4.0 90.0 10.0 80.0 False True False False 1.5 False 16.0 1.15221 3.0 False
|
| 4 |
+
S03 35.0 0.45857 n/a n/a False -0.0038151 2.0 False 2.0 n/a 3.0 10.0 0.894501 1.55556 False False 1.0 0.866667 3.6 40.0 0.0 9.0 False 11.5 10.0 0.5 30.0 10.0 40.0 False 0.25 10.0 0.0 3.0 0.715695 100.0 2.0 10.0 0.890686 3.0 33.0 5.0 63.0 42.0 n/a 9.0 0.0 2.0 0 False 4.0 True 3.0 0.995588 0.682245 False 30.0 False False 2.0 False 0.68254 n/a 15.0 30.0 15.0 30.0 50.0 70.0 d 20.0 50.0 4.0 False 0.0 True 0.0 False 4.0 False 2.0 0.658032 False False 1.0 12.0 10.0 0.816513 2.33333 animaux 5.0 0.0 60.0 0 n/a False 0.966338 False 2.0 4.0 0.217391 2.0 visages, lieux 4.0 100.0 204 n/a 12.0 0.815689 7.375 6.0 4.0 80.0 11.0 80.0 False False False False 2.5 False 14.0 0.740778 2.0 False
|
| 5 |
+
S04 20.0 0.240791 1.0 1.0 False 0.0366737 3.5 False 5.0 1.0 1.0 45.0 0.937822 1.58333 True True 2.0 0.766667 3.6 450.0 1.0 12.0 False 15.5 10.0 0.833333 15.0 10.0 25.0 False 0.333333 10.0 0.0 2.0 0.584904 70.0 2.0 9.0 0.974495 3.0 32.0 4.0 55.0 44.0 1.0 9.0 0.0 1.0 0 False 3.0 True 4.0 0.997322 0.356258 False 100.0 False False 3.0 False 0.358396 n/a 10.0 15.0 15.0 25.0 30.0 35.0 d 10.0 30.0 4.0 False 0.0 True 0.0 False 5.0 False 2.0 0.350432 False False 1.0 25.0 12.0 0.668016 4.0 LIEUX 7.0 2.0 50.0 0 n/a False 0.984509 False 0.0 2.0 0.225806 1.0 VISAGE 5.0 250.0 322 n/a 17.0 0.666625 5.52778 6.0 5.0 1.0 14.0 100.0 True True True False 3.5 False 19.0 0.791295 2.0 False
|
| 6 |
+
S05 40.0 0.3345 1.0 1.0 False -0.0530016 1.5 False 3.0 1.0 1.0 10.0 0.914142 1.77778 False True 0.0 0.433333 1.8 400.0 1.0 9.0 False 12.5 8.0 0.583333 20.0 10.0 30.0 False 0.0 9.0 0.0 2.0 0.635478 20.0 0.0 6.0 0.86114 3.0 23.0 3.0 60.0 40.0 1.0 4.0 0.0 3.0 0 True 2.0 True 0.0 0.991584 0.503873 False 50.0 False False 2.0 False 0.497873 n/a 15.0 30.0 20.0 30.0 45.0 50.0 n/a 15.0 40.0 2.0 False 0.0 True 4.0 False 3.0 False 1.0 0.917151 False False 1.0 10.0 10.0 0.724752 0.0 n/a 7.0 0.0 30.0 0 n/a False 1.01049 False 1.0 2.5 0.28 1.0 n/a 0.0 30.0 298 n/a 5.0 0.724264 6.40278 6.0 2.0 40.0 11.0 15.0 False True True True 1.0 False 16.0 1.02732 3.0 False
|
| 7 |
+
S06 30.0 0.52638 n/a n/a False -0.00565731 3.5 False 4.0 n/a 1.0 25.0 0.933403 2.0 False False 2.0 0.633333 3.6 400.0 n/a 9.0 False 13.5 8.0 0.75 20.0 10.0 50.0 False 0.0 10.0 2.0 3.0 0.834941 75.0 2.0 10.0 0.927745 3.0 34.0 4.0 64.0 43.0 n/a 8.0 0.0 3.0 0 False 2.0 True 5.0 0.998702 0.781213 False 20.0 True False 3.0 False 0.783469 n/a 10.0 20.0 20.0 50.0 50.0 70.0 u 20.0 50.0 2.0 True 0.0 True 5.0 False 5.0 False 2.0 0.881779 False False 1.0 15.0 10.0 0.951082 0.0 n/a 9.0 0.0 45.0 0 n/a True 1.01283 False 2.0 3.0 0.333333 1.0 LIEUX VISAGES 3.0 200.0 311 n/a 17.0 0.951596 8.0 4.0 4.0 75.0 10.0 75.0 False True False True 2.0 False 18.0 1.0508 n/a False
|
| 8 |
+
S07 60.0 0.887654 1.0 1.0 False -0.013893 2.0 False 3.0 1.0 1.0 10.0 0.923668 2.0 False True 1.0 0.7 3.8 300.0 1.0 11.0 True 16.5 7.0 0.666667 50.0 15.0 80.0 False 0.25 9.0 2.0 2.0 0.967964 10.0 0.0 10.0 0.909775 3.0 30.0 3.0 62.0 40.0 1.0 6.0 0.0 3.0 aprentissage lecture , difference d/t , p/b a 6ans duree 1ans False 4.0 True 5.0 0.994361 1.30039 False 50.0 False False 2.0 False 1.32119 n/a 10.0 40.0 30.0 100.0 80.0 100.0 d 30.0 100.0 2.0 True 0.0 True 6.0 False 3.0 False 1.0 0.884219 False False 1.0 4.0 10.0 1.09569 2.0 n/a 11.0 0.0 40.0 0 n/a True 1.03761 True 2.0 1.0 0.333333 1.0 LIEUX 4.0 30.0 333 n/a 8.0 1.1032 5.84722 6.0 5.0 40.0 10.0 30.0 False True True False 2.0 False 22.0 0.958523 1.0 False
|
| 9 |
+
S08 30.0 0.378301 n/a n/a False 0.0574613 3.0 False 4.0 n/a 2.0 5.0 0.914426 1.35714 False False 2.0 0.833333 7.0 350.0 n/a 14.0 False 16.5 64.0 0.416667 20.0 15.0 35.0 False 0.0 10.0 0.0 3.0 0.657123 80.0 2.0 10.0 0.971887 3.0 32.0 4.0 63.0 42.0 n/a 8.0 2.0 1.0 0 False 4.0 False 5.0 0.999458 0.551338 False 100.0 False False 3.0 True 0.563067 n/a 10.0 20.0 18.0 35.0 40.0 50.0 u 15.0 50.0 4.0 False 0.0 True 2.0 False 5.0 False 1.0 0.721875 False True 1.0 20.0 10.0 0.74894 4.0 LIEUX 5.0 0.0 30.0 0 n/a False 1.00225 False 0.0 1.5 0.151515 2.0 PHYSIONOMIE 4.0 100.0 290 n/a 16.0 0.748933 4.84722 8.0 4.0 90.0 10.0 80.0 False True False False 1.9 False 19.0 0.959285 3.0 False
|
| 10 |
+
S09 100.0 1.29591 n/a n/a False -0.0193175 4.0 False 3.0 n/a 1.0 12.0 0.943651 1.47826 False True 2.0 0.533333 2.9 800.0 n/a 11.5 False 14.25 10.0 0.5 80.0 15.0 100.0 False 0.2 10.0 0.0 2.0 1.03413 200.0 2.0 10.0 0.924333 3.0 35.0 3.0 55.0 42.0 n/a 6.0 0.0 3.0 0 False 3.0 True 2.0 0.988621 1.94941 False 50.0 False False 1.0 False 1.92885 n/a 20.0 50.0 35.0 110.0 130.0 160.0 u 25.0 120.0 3.0 False 0.0 True 2.0 False 4.0 False 1.0 0.85892 False False 1.0 15.0 8.0 1.18304 0.0 n/a 5.5 0.0 50.0 0 n/a False 1.03538 False 2.0 3.0 0.192982 1.0 LIEUX 2.0 300.0 336 n/a 18.0 1.17861 7.5 4.0 2.0 45.0 14.0 30.0 False True True False 1.5 False 17.0 1.22631 1.0 False
|
| 11 |
+
S10 43.0 0.534045 n/a n/a False 0.0017111 4.5 False 3.0 n/a 1.0 40.0 0.973282 1.66667 False True 2.0 0.6 4.2 500.0 0.0 9.0 True 12.0 10.0 0.583333 27.0 12.0 39.0 False 0.25 8.0 4.0 2.0 0.780877 50.0 2.0 10.0 0.974993 3.0 30.0 3.0 66.0 43.0 n/a 7.0 1.0 3.0 APPRENTISSAGE LECTURE/DYSLEXIE/BEGAIEMENT ZEZAIEMENT False 4.0 True 5.0 0.994773 0.792601 False 70.0 True False 2.0 False 0.794878 n/a 12.0 25.0 25.0 48.0 58.0 70.0 d 19.0 60.0 4.0 True 2.0 True 4.0 True 3.0 True 2.0 0.944997 False False 1.0 12.0 11.0 0.890339 2.33333 animaux 6.0 0.0 50.0 0 n/a True 1.05757 True 1.0 3.0 0.25 3.0 lieux 3.0 80.0 163 n/a 19.0 0.889978 8.06944 6.0 3.0 70.0 10.0 100.0 False True False False 3.0 False 15.0 0.999617 2.0 False
|
| 12 |
+
S11 50.0 0.501391 n/a n/a False -0.155042 3.5 False 4.0 n/a 1.0 25.0 0.877283 1.25 True True 2.0 0.466667 1.6 400.0 n/a 8.0 False 9.0 8.0 0.583333 30.0 10.0 40.0 False 0.0 10.0 0.0 2.0 0.786632 200.0 2.0 7.0 0.722241 3.0 30.0 5.0 70.0 41.0 n/a 6.0 0.0 3.0 MATHS False 2.0 True 1.0 0.994483 0.767568 False 80.0 False True 1.0 True 0.746275 n/a 16.0 38.0 20.0 75.0 55.0 70.0 d 16.0 40.0 2.0 False 3.0 True 1.0 False 4.0 False 2.0 0.918997 False True 1.0 15.0 11.0 0.901555 2.66667 0 2.0 3.0 46.0 Lettres, chiffres, sons, temps, en espace et en couleur n/a False 0.973921 False 2.0 n/a 0.111111 3.0 visages, lieux 1.0 90.0 176 n/a 17.0 0.896537 4.81944 6.0 1.0 80.0 16.0 80.0 False True n/a False 3.0 True 10.0 1.03446 2.0 False
|
| 13 |
+
S12 40.0 0.45318 n/a n/a False -0.0294667 0.5 False 4.0 n/a 2.0 5.0 0.923912 1.75 False True 1.0 0.633333 3.2 500.0 n/a 12.0 False 16.5 8.0 0.5 35.0 12.0 37.0 False 0.25 8.0 2.0 3.0 0.722995 20.0 1.0 7.0 0.894445 3.0 32.0 4.0 60.0 45.0 n/a 8.0 1.0 3.0 FRANCAIS ORTHOGRAPHE LECTURE False 3.0 True 3.0 0.999026 0.676939 False 100.0 False False 3.0 False 0.674518 n/a 12.0 30.0 25.0 35.0 50.0 70.0 u 15.0 50.0 2.0 True 0.0 True 4.0 False 3.0 False 1.0 0.883083 False False 1.0 8.0 15.0 0.822753 3.33333 0 9.0 0.0 56.0 n/a n/a True 1.00245 False 1.0 1.5 0.272727 2.0 0 4.0 40.0 182 n/a 7.0 0.824009 5.91667 6.0 4.0 50.0 11.0 80.0 True True True True 2.0 False 21.0 1.08707 2.0 True
|
| 14 |
+
S13 30.0 0.553522 1.0 1.0 False -0.0442015 3.5 False 3.0 1.0 1.0 12.0 0.962172 1.54545 False True 2.0 1.0 3.8 350.0 1.0 11.0 False 14.0 10.0 0.666667 25.0 10.0 50.0 False 0.2 10.0 0.0 4.0 0.840788 80.0 2.0 10.0 0.91797 3.0 33.0 4.0 70.0 44.0 1.0 10.0 0.0 3.0 0 False 3.0 True 4.0 0.999519 0.797884 False 75.0 False False 3.0 False 0.823867 n/a 12.0 30.0 20.0 59.0 55.0 60.0 d 20.0 70.0 2.0 False 0.0 True 2.0 False 5.0 False 1.0 0.96621 False False 1.0 10.0 15.0 0.94617 5.0 n/a 6.0 0.0 60.0 0 n/a False 1.02888 False 2.0 1.5 0.214286 1.0 LIEUX 5.0 100.0 318 n/a 17.0 0.958259 6.84722 4.0 5.0 85.0 12.0 80.0 False True False False 2.5 False 17.0 1.04223 2.0 False
|
| 15 |
+
S14 40.0 0.536215 n/a n/a False -0.0167022 1.5 False 4.0 n/a 1.0 7.0 0.982381 1.90909 False False 1.0 0.8 3.4 350.0 n/a 11.0 False 16.0 9.0 0.75 25.0 10.0 50.0 False 0.11 10.0 0.0 3.0 0.842689 50.0 1.0 10.0 0.965678 3.0 36.0 4.0 62.0 45.0 n/a 9.0 0.0 3.0 0 False 3.0 True 3.0 0.997089 0.788024 False 60.0 False False 3.0 False 0.798107 n/a 12.0 30.0 20.0 40.0 50.0 70.0 d 15.0 60.0 4.0 False 0.0 True 2.0 False 4.0 False 2.0 0.910639 False False 1.0 20.0 10.0 0.955723 3.33333 0 10.0 0.0 50.0 n/a n/a False 1.01764 False 2.0 2.5 0.3125 1.0 LIEUX VISAGES 4.0 100.0 219 n/a 9.0 0.960426 7.14583 5.0 3.0 60.0 10.0 30.0 False True True n/a 4.0 False 21.0 0.927176 2.0 False
|
| 16 |
+
S15 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a 366 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a
|
| 17 |
+
S16 55.0 0.432409 n/a n/a False -0.114653 2.0 False 3.0 n/a 1.0 40.0 0.930288 2.0 False False 1.0 0.633333 3.4 350.0 n/a 7.0 False 10.5 8.0 0.666667 30.0 10.0 55.0 False 0.0 9.0 0.0 2.0 0.735609 50.0 1.0 8.0 0.815635 3.0 30.0 4.0 67.0 43.0 n/a 6.0 0.0 3.0 0 False 4.0 True 3.0 0.99974 0.651471 False 100.0 False False 2.0 False 0.643601 n/a 15.0 35.0 25.0 45.0 50.0 60.0 d 20.0 50.0 4.0 False 0.0 True 3.0 False 3.0 False 2.0 0.896679 False False 1.0 15.0 15.0 0.835647 2.33333 0 7.0 2.0 50.0 n/a n/a False 1.01069 False 1.0 3.5 0.333333 2.0 physionomie 3.0 40.0 194 n/a 10.0 0.838385 7.74306 7.0 3.0 45.0 10.0 80.0 False True n/a False 2.0 True 14.0 0.951493 2.0 False
|
| 18 |
+
S17 50.0 1.90848 n/a n/a False 0.00262361 5.0 False 2.0 n/a 1.0 20.0 0.934938 2.0 True True 2.0 0.266667 1.8 200.0 n/a 11.0 False 16.5 8.0 0.416667 20.0 10.0 100.0 False 0.0 8.0 0.0 n/a 1.48161 30.0 2.0 7.0 0.937562 3.0 30.0 5.0 60.0 40.0 n/a 0.0 1.0 3.0 0 False 3.0 True 4.0 0.995747 2.7377 False 200.0 False False 2.0 False 2.8406 n/a 10.0 50.0 20.0 100.0 130.0 200.0 u 10.0 200.0 3.0 False 0.0 True 2.0 False 3.0 False 2.0 0.744411 False False 1.0 50.0 8.0 1.67618 2.0 0 11.0 2.0 57.0 0 n/a False 0.944038 False 1.0 3.0 0.333333 3.0 Visages 3.0 150.0 205 n/a 20.0 1.68861 8.18056 4.0 3.0 50.0 11.0 100.0 False True False False 2.0 False 22.0 0.940993 3.0 False
|
| 19 |
+
S18 40.0 2.15291 1.0 1.0 False -0.169848 3.5 False 3.0 1.0 1.0 10.0 0.890863 1.41667 False True 2.0 0.466667 3.0 300.0 1.0 12.0 False 14.5 9.0 0.583333 35.0 7.0 40.0 False 0.5 10.0 1.0 2.0 1.41522 20.0 2.0 10.0 0.721015 3.0 30.0 4.0 63.0 43.0 1.0 4.0 0.0 1.0 0 False 2.0 True 3.0 1.0 2.99655 False 10.0 False False 2.0 False 3.20441 n/a 10.0 35.0 25.0 70.0 150.0 200.0 u 20.0 300.0 3.0 True 0.0 True 2.0 False 5.0 False 2.0 0.764588 False False 1.0 4.0 15.0 1.59256 0.0 n/a 5.0 0.0 50.0 0 n/a True 1.0 False 1.0 3.0 0.172414 2.0 VISAGES 1.0 10.0 332 n/a 17.0 1.61294 5.98611 6.0 2.0 80.0 12.0 50.0 False True True True 1.5 False 17.0 0.944911 2.0 False
|
| 20 |
+
S19 40.0 0.396693 n/a n/a False -0.018355 1.0 True 3.0 n/a 2.0 10.0 0.958646 1.64286 True False 1.0 0.5 3.4 600.0 n/a 14.0 False 18.5 8.5 0.666667 30.0 14.0 45.0 False 0.0 6.0 4.0 2.0 0.623431 50.0 0.0 8.0 0.940291 3.0 25.0 4.0 59.0 42.0 n/a 5.0 0.0 3.0 DYSLEXIE DYSORTHOGRAPHIE PB EXPRESSION False 2.0 True 4.0 0.997793 0.589586 False 60.0 True True 2.0 False 0.590441 n/a 15.0 35.0 20.0 45.0 50.0 58.0 d 25.0 50.0 1.0 True 1.0 True 3.0 False 4.0 True 1.0 0.969703 False False 1.0 12.0 11.0 0.708503 2.0 0 9.0 2.0 40.0 0 n/a False 0.970941 True 2.0 4.0 0.243243 1.0 lieux 2.0 110.0 183 n/a 6.0 0.710534 8.53472 5.0 2.0 50.0 10.0 60.0 False True False True 1.5 False 23.0 1.14744 3.0 True
|
| 21 |
+
S20 65.0 0.580366 n/a n/a False -0.0676551 2.5 False 4.0 n/a 1.0 15.0 0.938926 1.875 False True 1.0 0.833333 2.0 300.0 n/a 8.0 False 11.5 8.0 0.666 30.0 15.0 45.0 False 0.0 9.0 0.0 3.0 0.757288 100.0 1.0 9.0 0.871271 3.0 30.0 5.0 63.0 45.0 n/a 8.0 0.0 3.0 0 False 4.0 True 2.0 0.996139 0.879881 False 50.0 False False 2.0 False 0.863822 n/a 15.0 40.0 25.0 50.0 70.0 80.0 d 20.0 60.0 3.0 False 0.0 True 2.0 False 5.0 False 2.0 0.675853 False True 1.0 10.0 20.0 0.867901 3.5 0 7.0 0.0 50.0 n/a n/a False 0.96733 False 1.0 3.0 0.304348 2.0 Visages 3.0 25.0 166 n/a 11.0 0.863093 7.51333 4.0 3.0 70.0 13.0 500.0 False True False False 7.0 False 15.0 0.861326 2.0 False
|
| 22 |
+
S21 75.0 0.827894 n/a n/a False -0.0550406 1.0 False 3.0 n/a 3.0 10.0 0.933896 1.5 False True 1.0 0.6 2.8 500.0 n/a 10.0 False 12.5 11.0 0.25 25.0 10.0 60.0 False 0.2 6.0 0.0 3.0 0.97081 30.0 0.0 9.0 0.878856 3.0 30.0 5.0 60.0 40.0 n/a 4.0 0.0 1.0 n/a False 4.0 True 2.0 0.995747 1.23959 False 20.0 False False 3.0 False 1.23225 n/a 15.0 40.0 25.0 45.0 90.0 100.0 d 20.0 85.0 3.0 False 0.0 True 2.0 False 4.0 False 2.0 0.885648 False False 0.0 10.0 13.0 1.10749 3.0 lieux 5.0 0.0 100.0 n/a n/a False 0.944038 False 0.0 0.0 0.2 1.0 visage 3.0 40.0 104 n/a 4.0 1.10645 1.875 12.0 3.0 60.0 11.0 80.0 False True True False 3.0 False 15.0 0.975003 2.0 False
|
| 23 |
+
S22 50.0 0.310351 n/a n/a False -0.249045 4.0 False 5.0 n/a 1.0 20.0 0.783854 1.5 False False 2.0 0.866667 4.4 300.0 n/a 12.0 False 15.0 7.0 0.666667 20.0 10.0 35.0 False 0.0 9.0 0.0 4.0 0.695147 50.0 2.0 10.0 0.534809 3.0 28.0 4.0 62.0 45.0 n/a 10.0 0.0 3.0 0 False 4.0 True 5.0 0.999154 0.471502 False 40.0 False False 3.0 False 0.461929 n/a 10.0 50.0 20.0 30.0 40.0 50.0 d 15.0 35.0 4.0 False 0.0 True 2.0 False 5.0 False 2.0 0.977155 False True 1.0 15.0 10.0 0.786574 4.33333 0 6.0 0.0 40.0 0 n/a False 0.997375 False 0.0 4.0 0.2 3.0 Visages 4.0 80.0 188 n/a 18.0 0.79227 9.20139 5.0 5.0 70.0 10.0 50.0 False True False False 2.5 False 18.0 0.955999 3.0 False
|
| 24 |
+
S23 50.0 0.508968 1.0 1.0 False -0.0350254 2.5 False 3.0 1.0 1.0 10.0 0.871767 1.54545 False True 1.0 0.433333 2.8 800.0 1.0 11.0 False 14.0 5.0 0.5 20.0 10.0 30.0 False 0.0 10.0 0.0 2.0 0.800143 15.0 0.0 10.0 0.836741 3.0 23.0 4.0 64.0 44.0 1.0 3.0 0.0 3.0 0 False 4.0 True 2.0 0.992409 0.7681 False 30.0 False True 2.0 False 0.757553 n/a 15.0 40.0 15.0 40.0 60.0 70.0 u 15.0 50.0 2.0 False 0.0 True 3.0 False 4.0 False 1.0 0.855351 False False 1.0 10.0 10.0 0.916341 0.0 n/a 6.0 0.0 40.0 0 n/a False 0.984198 False 1.0 2.0 0.214286 2.0 n/a 2.0 40.0 323 n/a 9.0 0.911936 6.14583 7.0 2.0 50.0 10.0 200.0 False True True False 2.0 False 17.0 1.14246 2.0 False
|
| 25 |
+
S24 60.0 0.671362 1.0 1.0 False -0.0573619 3.0 False 3.0 1.0 2.0 25.0 0.944763 0.947368 True True 2.0 0.5 3.2 300.0 1.0 19.0 False 18.5 8.0 0.333333 35.0 10.0 75.0 False 0.0 9.0 0.0 2.0 0.951386 600.0 1.0 9.0 0.887401 3.0 34.0 3.0 57.0 45.0 1.0 6.0 0.0 1.0 0 False 2.0 True 2.0 0.990636 1.00301 False 45.0 False True 1.0 False 0.999262 n/a 10.0 35.0 25.0 60.0 70.0 80.0 u 25.0 70.0 2.0 False 0.0 True 2.0 False 3.0 False 0.0 0.673082 False False 1.0 20.0 20.0 1.08045 0.0 VISAGES -1.0 2.0 30.0 0 n/a False 1.04792 False 2.0 1.5 -0.027027 1.0 LIEUX 3.0 500.0 335 n/a 14.0 1.08431 4.13194 7.0 4.0 90.0 10.0 300.0 False True True True 3.0 False 18.0 1.06108 2.0 False
|
| 26 |
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S25 50.0 0.688949 1.0 1.0 False -0.0489149 1.0 False 4.0 1.0 1.0 20.0 0.948051 2.0 False True 0.0 0.566667 3.0 500.0 0.0 10.0 False 15.0 8.5 0.666667 40.0 10.0 60.0 False 0.0 10.0 0.0 3.0 0.875224 800.0 1.0 10.0 0.899136 3.0 40.0 5.0 76.0 35.0 1.0 7.0 0.0 3.0 n/a False 2.0 True 2.0 0.979872 1.04007 False 70.0 False False 2.0 False 1.02544 n/a 15.0 30.0 25.0 50.0 70.0 100.0 u 20.0 60.0 4.0 False 0.0 True 1.0 False 4.0 False 1.0 0.575015 False False 1.0 4.0 15.0 1.00105 3.33333 animaux 10.0 2.0 50.0 0 n/a False 0.991503 False 1.0 2.5 0.333333 2.0 n/a 3.0 10.0 9 n/a 6.0 0.997507 7.05556 4.0 3.0 50.0 16.0 6.0 False True False False 1.2 True 20.0 1.09846 3.0 False
|
| 27 |
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S26 35.0 0.455105 n/a n/a False -0.00552304 1.0 False 2.0 n/a 2.0 5.0 0.96991 2.07692 True True 1.0 0.433333 1.8 240.0 n/a 13.0 True 20.0 12.0 0.25 20.0 10.0 35.0 False 0.2 9.0 3.0 1.0 0.801922 5.0 0.0 10.0 0.964387 3.0 32.0 5.0 64.0 43.0 n/a 4.0 1.0 3.0 dyslexie, pblm de: lecture, inversion de syllabes,dorganisation, emploi du tps False 4.0 True 4.0 0.996225 0.68226 False 10.0 True False 1.0 False 0.677383 n/a 10.0 20.0 17.0 40.0 50.0 60.0 d 15.0 45.0 2.0 True 0.0 True 3.0 False 4.0 True 2.0 0.610165 False False 1.0 6.0 7.0 0.919298 0.0 n/a 14.0 3.0 50.0 0 n/a False 0.969552 True 2.0 2.0 0.35 3.0 VISAGES LIEUX 3.0 15.0 347 n/a 6.0 0.913964 6.52083 5.0 3.0 60.0 10.0 4.0 False True True True 1.5 True 27.0 0.830617 3.0 False
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| 28 |
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S27 30.0 0.400822 1.0 1.0 False -0.0253511 2.0 False 4.0 1.0 2.0 4.0 0.941145 1.38462 False False 0.0 0.966667 4.2 300.0 1.0 13.0 False 15.5 8.0 0.75 20.0 10.0 40.0 False 0.0 10.0 0.0 3.0 0.676112 60.0 1.0 10.0 0.915794 3.0 27.0 4.0 65.0 42.0 1.0 10.0 0.0 3.0 0 False 4.0 True 4.0 0.998677 0.60153 False 80.0 False False 3.0 False 0.596588 n/a 15.0 30.0 20.0 40.0 50.0 60.0 d 20.0 40.0 4.0 False 0.0 True 1.0 False 4.0 False 2.0 0.870445 False True 1.0 15.0 16.0 0.768781 3.0 n/a 5.0 0.0 80.0 0 n/a False 0.993971 False 1.0 1.5 0.16129 1.0 VISAGES 4.0 100.0 331 n/a 8.0 0.770575 6.22917 7.0 4.0 50.0 11.0 100.0 False True False False 2.0 False 18.0 1.06635 2.0 False
|
| 29 |
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S28 53.0 1.08503 n/a n/a False -0.0193036 4.0 False 3.0 n/a 3.0 15.0 0.918141 1.77778 True False 2.0 0.666667 3.2 600.0 n/a 9.0 False 12.5 8.0 0.583333 20.0 10.0 55.0 False 0.0 10.0 0.0 3.0 1.09877 25.0 2.0 9.0 0.898837 3.0 25.0 4.0 65.0 42.0 n/a 7.0 0.0 3.0 0 False 2.0 True 5.0 0.99648 1.60522 False 30.0 False False 2.0 False 1.61497 n/a 15.0 25.0 25.0 105.0 76.0 135.0 u 15.0 90.0 3.0 False 0.0 True 2.0 False 4.0 False 2.0 0.814187 False False 1.0 9.0 16.0 1.25582 2.0 n/a 7.0 2.0 50.0 0 n/a False 0.987764 False 1.0 1.5 0.28 3.0 VIGAGE 5.0 50.0 294 n/a 18.0 1.25228 6.56944 8.0 5.0 70.0 13.0 50.0 False True False True 12.0 False 16.0 0.81182 2.0 False
|
| 30 |
+
S29 34.0 0.403552 n/a n/a False -0.032888 3.5 False 3.0 n/a 2.0 5.0 0.915869 1.8 False True 2.0 0.433333 3.0 800.0 2.0 10.0 False 14.0 10.0 0.666667 15.0 10.0 30.0 False 0.0 8.0 0.0 3.0 0.737564 500.0 2.0 10.0 0.882981 3.0 33.0 4.0 57.0 42.0 1.0 5.0 0.0 3.0 0 False 2.0 True 4.0 0.997662 0.613726 False 40.0 False False 2.0 False 0.600651 n/a 10.0 20.0 20.0 35.0 47.0 60.0 d 15.0 35.0 4.0 False 0.0 True 1.0 False 4.0 False 2.0 0.404527 False False 1.0 10.0 15.0 0.84771 0.0 n/a 8.0 0.0 40.0 0 n/a False 0.987342 False 1.0 1.5 0.285714 3.0 VISAGES ANIMAUX 4.0 500.0 330 n/a 17.0 0.840613 7.01389 4.0 4.0 1.0 11.0 300.0 False True False False 3.0 False 18.0 1.08016 3.0 False
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| 31 |
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S30 60.0 0.46732 n/a n/a False -0.281506 1.0 False 4.0 n/a 1.0 50.0 0.818848 1.88889 False False 0.0 0.566667 3.6 400.0 n/a 9.0 False 13.0 10.0 0.75 30.0 10.0 40.0 False 0.5 9.0 0.0 3.0 0.757308 70.0 1.0 8.0 0.537342 3.0 25.0 5.0 62.0 42.0 n/a 7.0 0.0 3.0 0 False 4.0 True 4.0 0.9921 0.72291 False 250.0 False False 2.0 False 0.695564 n/a 15.0 40.0 30.0 90.0 60.0 60.0 u 20.0 40.0 3.0 False 0.0 True 3.0 False 3.0 False 2.0 0.78383 False False 1.0 15.0 15.0 0.864595 3.33333 0 8.0 0.0 50.0 nombre / espace n/a False 0.941167 False 1.0 4.0 0.307692 1.0 Visages 3.0 60.0 177 n/a 6.0 0.863115 8.60417 5.0 2.0 50.0 10.0 20.0 False True False False 1.0 False 17.0 1.05261 3.0 False
|
| 32 |
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S31 40.0 0.580558 n/a n/a False 0.0131732 2.5 False 4.0 n/a 2.0 5.0 0.967509 1.46154 False True 1.0 0.533333 4.4 800.0 n/a 13.0 False 16.0 11.0 0.666667 20.0 11.0 40.0 False 0.0 10.0 0.0 1.0 0.868769 200.0 1.0 10.0 0.980682 3.0 30.0 4.0 63.0 45.0 n/a 4.0 0.0 2.0 0 False 4.0 True 3.0 0.999827 0.86083 False 600.0 False False 2.0 False 0.864108 n/a 12.0 25.0 18.0 50.0 60.0 70.0 d 14.0 60.0 4.0 False 0.0 True 5.0 False 4.0 False 0.0 0.789305 False False 1.0 7.0 12.0 0.993075 4.0 VISAGE 6.0 0.0 50.0 0 n/a False 1.00572 False 2.0 3.0 0.1875 2.0 LIEUX 3.0 150.0 295 n/a 11.0 0.99015 6.74306 5.0 4.0 80.0 10.0 300.0 False True True False 2.5 False 19.0 1.33373 2.0 False
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| 33 |
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S32 60.0 1.50179 n/a n/a False -0.0628016 0.0 False 4.0 n/a 1.0 10.0 0.937975 1.57143 False True 0.0 0.833333 3.6 500.0 0.0 14.0 False 18.0 7.0 n/a 40.0 15.0 120.0 False 0.0 10.0 0.0 3.0 1.12305 20.0 0.0 8.0 0.875174 3.0 27.0 4.0 64.0 43.0 n/a 9.0 0.0 1.0 0 False 4.0 True 5.0 0.998799 2.15269 False 60.0 False False 3.0 False 2.23528 n/a 15.0 40.0 30.0 150.0 100.0 150.0 d 30.0 170.0 4.0 False 1.0 True 0.0 False 4.0 False 0.0 0.866485 False False 1.0 10.0 15.0 1.26973 3.33333 Visages animaux 8.0 0.0 40.0 0 n/a False 0.994238 False 2.0 2.5 0.222222 1.0 lieux 5.0 150.0 185 n/a 2.0 1.27996 4.5625 5.0 5.0 80.0 14.0 15.0 True True False False 2.0 False 22.0 1.06178 n/a False
|
| 34 |
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S33 80.0 1.00954 n/a n/a False -0.037087 2.0 False 3.0 n/a 3.0 6.0 0.970922 1.875 True True 1.0 0.733333 2.8 400.0 n/a 8.0 True 11.5 11.0 0.583333 35.0 10.0 90.0 False 0.2 7.0 2.0 4.0 1.07425 30.0 2.0 9.0 0.933835 3.0 32.0 4.0 65.0 42.0 n/a 10.0 0.0 3.0 apprentissage lecture False 3.0 True 4.0 0.999484 1.50266 False 80.0 False False 2.0 False 1.5026 n/a 15.0 50.0 25.0 90.0 100.0 110.0 u 25.0 100.0 3.0 True 0.0 True 1.0 False 5.0 False 1.0 0.882616 False False 1.0 20.0 15.0 1.22089 3.33333 0 7.0 2.0 100.0 0 n/a True 1.00767 False 1.0 2.0 0.304348 2.0 0 3.0 150.0 216 n/a 12.0 1.22434 6.61111 6.0 4.0 80.0 10.0 70.0 False True False False 2.5 False 15.0 1.04328 1.0 False
|
| 35 |
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S34 39.0 0.546959 n/a n/a False -0.0169346 3.5 False 2.0 n/a 1.0 20.0 0.978523 1.77778 False False 2.0 0.766667 3.0 350.0 n/a 9.0 False 12.5 8.0 1.0 29.0 13.0 55.0 False 0.33 10.0 0.0 2.0 0.790664 50.0 2.0 10.0 0.961589 3.0 33.0 4.0 72.0 44.0 n/a 9.0 0.0 3.0 timbre de voix False 3.0 True n/a 0.999336 0.808399 False 90.0 False False 2.0 False 0.8141 n/a 13.0 36.0 21.0 50.0 60.0 70.0 d 18.0 60.0 4.0 False 0.0 True 0.0 False 3.0 False 1.0 0.95104 True False 1.0 17.0 13.0 0.897307 1.66667 0 7.0 0.0 40.0 n/a n/a False 1.03377 True 2.0 3.0 0.28 2.0 lieux 2.0 50.0 191 n/a 17.0 0.901132 7.875 4.0 2.0 75.0 16.0 100.0 False True True False 3.0 False 16.0 0.952927 3.0 False
|
| 36 |
+
S35 45.0 0.739662 n/a n/a False -0.0104976 3.0 False 4.0 n/a 1.0 4.0 0.956899 2.1 True False 1.0 0.533333 2.4 350.0 n/a 10.0 False 15.5 9.0 0.833333 30.0 12.0 50.0 False 0.6 7.0 0.0 1.0 0.966636 30.0 0.0 8.0 0.946401 3.0 32.0 4.0 70.0 43.0 n/a 3.0 0.0 1.0 positionement main gauche False 4.0 True 4.0 0.999391 1.07854 False 8.0 False False 2.0 False 1.10092 n/a 10.0 30.0 30.0 75.0 70.0 80.0 d 15.0 85.0 3.0 False 1.0 True 2.0 False 4.0 False 1.0 0.814216 True False 1.0 5.0 6.0 1.09427 2.66667 0 11.0 2.0 60.0 0 n/a False 1.02351 True 1.0 4.0 0.354839 1.0 0 4.0 60.0 192 n/a 10.0 1.10169 6.90278 6.0 1.0 50.0 13.0 20.0 True True False False 2.5 False 21.0 0.995345 2.0 False
|
| 37 |
+
S36 24.0 0.373996 n/a n/a False 0.0331708 0.5 False 4.0 n/a 1.0 4.0 0.885147 2.22222 False True 0.0 0.8 2.8 450.0 n/a 9.0 False 14.5 7.0 0.583333 20.0 11.0 39.0 False 0.5 9.0 0.0 3.0 0.668698 167.0 0.0 9.0 0.918318 3.0 28.0 4.0 55.0 43.0 n/a 7.0 0.0 3.0 0 False 4.0 True 2.0 0.998932 0.556324 False 30.0 False False 3.0 False 0.556659 n/a 13.0 15.0 16.0 35.0 45.0 50.0 u 15.0 41.0 4.0 False 0.0 True 2.0 False 4.0 False 1.0 0.856854 False True 1.0 7.0 11.0 0.768194 3.66667 0 11.0 0.0 45.0 0 n/a False 0.970847 False 1.0 1.0 0.37931 2.0 tout 2.0 30.0 200 n/a 3.0 0.762126 5.50694 5.0 2.0 70.0 12.0 40.0 False True True False 2.5 False 20.0 1.08659 3.0 False
|
| 38 |
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S37 60.0 1.20749 n/a n/a False 0.00848409 4.0 False 0.0 n/a 3.0 20.0 0.911086 1.33333 False False 2.0 0.733333 3.8 300.0 n/a 9.0 False 10.5 9.0 0.833333 45.0 15.0 85.0 False 0.0 6.0 0.0 0.0 0.988676 60.0 2.0 10.0 0.91957 3.0 30.0 4.0 64.0 44.0 n/a 8.0 0.0 3.0 0 False 4.0 True 3.0 0.999972 1.76399 False 45.0 False False 3.0 False 1.79724 n/a 16.0 26.0 30.0 60.0 100.0 150.0 d 25.0 130.0 4.0 False 0.0 True 5.0 False 0.0 False 1.0 0.957402 False True 1.0 15.0 12.0 1.12971 0.0 n/a 3.0 0.0 50.0 0 n/a False 1.00563 False 2.0 4.0 0.142857 1.0 LIEUX,VISAGE 5.0 35.0 291 n/a 18.0 1.12681 8.63194 7.0 2.0 90.0 13.0 80.0 False True True False 2.5 False 12.0 0.938097 2.0 False
|
| 39 |
+
S38 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a 368 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a
|
| 40 |
+
S39 50.0 0.621052 n/a n/a False -0.0259647 0.5 False 5.0 n/a 1.0 25.0 0.923161 1.58333 False False 0.0 0.733333 2.8 800.0 n/a 12.0 False 15.5 10.0 0.666667 25.0 10.0 30.0 False 0.0 9.0 0.0 4.0 0.840421 110.0 0.0 10.0 0.897196 3.0 30.0 5.0 61.0 41.0 n/a 10.0 0.0 3.0 LANGUES False 4.0 True 5.0 0.995976 0.934155 False 50.0 False False 2.0 False 0.924379 n/a 15.0 30.0 20.0 60.0 70.0 80.0 d 20.0 60.0 2.0 False 0.0 True 2.0 False 4.0 False 2.0 0.947885 True False 1.0 13.0 10.0 0.962968 4.0 0 7.0 0.0 58.0 n/a n/a False 0.950016 False 2.0 4.0 0.225806 1.0 visages, lieux 4.0 100.0 139 n/a 3.0 0.957841 8.68056 4.0 5.0 80.0 10.0 30.0 False True False True 2.0 False 19.0 1.13179 3.0 False
|
| 41 |
+
S40 60.0 0.669262 n/a n/a False -0.120663 3.0 False 4.0 n/a 1.0 6.0 0.869703 1.26667 False True 2.0 0.85 2.8 400.0 n/a 15.0 False 17.0 6.0 0.75 30.0 12.0 35.0 False 0.29 10.0 0.0 3.0 0.798569 80.0 1.0 10.0 0.74904 3.0 22.0 3.0 61.0 42.0 0.0 7.0 0.0 2.0 0 False 4.0 True 2.0 0.988815 1.03409 False 100.0 False False 1.0 True 0.996137 n/a 15.0 30.0 28.0 50.0 70.0 110.0 d 18.0 45.0 4.0 False 0.0 True 0.0 False 3.0 False 2.0 0.917762 False False 1.0 7.0 18.0 0.923717 3.5 lieux 4.0 0.0 60.0 Chiffres lettres, noms, mots / couleurs, prenoms / gout, toucher, nombres / temps n/a False 1.01591 False 1.0 2.0 0.117647 2.0 Visages 3.0 50.0 197 n/a 14.0 0.910141 5.83333 6.0 2.0 70.0 10.0 90.0 False True False False 2.0 False 19.0 1.1343 2.0 False
|
| 42 |
+
S41 50.0 0.634911 n/a n/a False -0.123459 1.5 False 4.0 n/a 3.0 6.0 0.911603 1.33333 False True 0.0 0.8 5.0 400.0 n/a 12.0 False 14.0 10.0 0.583333 25.0 10.0 40.0 False 0.0 10.0 0.0 3.0 0.892371 60.0 1.0 10.0 0.788143 3.0 27.0 3.0 63.0 41.0 n/a 10.0 0.0 3.0 0 False 2.0 True 2.0 0.994467 0.985329 False 75.0 False False 2.0 False 0.945008 n/a 12.0 30.0 20.0 50.0 80.0 90.0 d 15.0 40.0 4.0 False 0.0 True 1.0 False 5.0 False 1.0 0.910247 False False 1.0 20.0 10.0 1.03135 2.0 n/a 4.0 0.0 50.0 0 n/a False 1.035 False 1.0 1.0 0.142857 1.0 n/a 4.0 80.0 348 n/a 7.0 1.01705 5.29861 7.0 4.0 40.0 11.0 50.0 False True True False 3.0 False 16.0 0.979685 2.0 False
|
| 43 |
+
S42 70.0 0.971599 n/a n/a False -0.0145183 3.0 False 3.0 n/a 3.0 20.0 0.93927 1.83333 False False 1.0 0.9 3.4 500.0 n/a 12.0 False 17.0 10.0 0.666667 30.0 15.0 77.0 False 0.0 10.0 0.0 2.0 0.955744 50.0 1.0 10.0 0.924752 3.0 32.0 4.0 65.0 44.0 2.0 10.0 0.0 3.0 0 True 4.0 True 4.0 0.99983 1.46297 False 250.0 False False 3.0 False 1.44614 n/a 15.0 40.0 20.0 70.0 90.0 130.0 d 25.0 80.0 4.0 False 0.0 True 0.0 False 4.0 False 2.0 0.893647 False False 1.0 15.0 15.0 1.09782 2.0 n/a 10.0 0.0 70.0 0 n/a False 1.01353 False 2.0 2.0 0.294118 3.0 VISAGE, LIEUX,PHYSIONOMIE 5.0 130.0 324 n/a 12.0 1.08928 6.53472 9.0 4.0 65.0 11.0 50.0 False True False False 4.0 False 22.0 1.00161 2.0 False
|
| 44 |
+
S43 50.0 0.444483 n/a n/a False -0.0592845 2.5 False 3.0 n/a 2.0 35.0 0.889422 1.91667 False False 2.0 0.933333 3.2 600.0 n/a 12.0 False 17.5 7.0 0.916667 25.0 15.0 40.0 False 0.0 10.0 0.0 2.0 0.608799 40.0 1.0 10.0 0.830138 3.0 22.0 4.0 68.0 43.0 n/a 9.0 1.0 3.0 0 False 2.0 True 3.0 0.988576 0.669578 False 100.0 False False 2.0 False 0.661573 n/a 20.0 50.0 25.0 50.0 60.0 70.0 u 25.0 50.0 4.0 False 0.0 True 1.0 False 4.0 False 0.0 0.8933 False False 1.0 12.0 18.0 0.692751 3.0 VISAGES 11.0 0.0 50.0 0 n/a False 0.988251 False 2.0 3.0 0.314286 1.0 LIEUX 5.0 40.0 349 n/a 13.0 0.693858 7.93056 6.0 4.0 60.0 12.0 25.0 False True False True 2.5 False 23.0 0.986973 3.0 False
|
| 45 |
+
S44 60.0 1.05413 n/a n/a False -0.0291271 5.0 False 4.0 n/a 2.0 10.0 0.913654 1.07692 False True 2.0 0.666667 2.4 600.0 n/a 13.0 False 13.5 10.0 0.833333 50.0 15.0 65.0 False 0.0 10.0 0.0 3.0 0.863541 20.0 2.0 7.0 0.884527 3.0 25.0 5.0 55.0 42.0 n/a 10.0 0.0 3.0 0 False 4.0 True 2.0 0.99285 1.59484 False 100.0 False True 2.0 True 1.56897 n/a 25.0 40.0 25.0 78.0 115.0 150.0 u 30.0 85.0 3.0 False 1.0 True 2.0 False 3.0 False 2.0 0.6925 False False 1.0 6.0 15.0 0.99406 0.0 n/a 1.0 0.0 50.0 0 n/a False 0.920358 False 2.0 1.5 0.037037 3.0 VISAGE ET LIEUX 2.0 15.0 293 n/a 20.0 0.984191 6.73611 6.0 1.0 80.0 13.0 6.0 False True False False 3.0 False 14.0 0.943294 3.0 False
|
| 46 |
+
S45 30.0 0.287899 n/a n/a False -0.0142111 1.5 False 4.0 n/a 3.0 30.0 0.89745 2.4 False True 1.0 0.733333 3.4 600.0 n/a 10.0 False 17.0 6.0 0.583333 20.0 6.0 20.0 False 0.25 9.0 0.0 3.0 0.706925 80.0 1.0 9.0 0.883239 3.0 27.0 5.0 70.0 45.0 n/a 7.0 0.0 3.0 0 False 4.0 True 3.0 0.992768 0.419834 False 30.0 False False 2.0 False 0.428512 n/a 12.0 25.0 15.0 30.0 30.0 40.0 u 12.0 40.0 2.0 False 0.0 True 2.0 False 5.0 False 1.0 0.912762 False False 1.0 8.0 12.0 0.796829 3.33333 0 14.0 0.0 40.0 0 n/a False 0.977134 False 2.0 2.5 0.411765 1.0 lieux 3.0 60.0 170 n/a 9.0 0.805694 7.23611 6.0 3.0 50.0 10.0 100.0 False True False False 3.0 False 24.0 1.04265 4.0 False
|
| 47 |
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| 48 |
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S47 50.0 0.747239 n/a n/a False -0.0657451 4.0 False 4.0 n/a 2.0 n/a 0.91669 1.81818 False True 2.0 0.533333 3.6 n/a n/a 11.0 False 15.5 n/a 0.916667 25.0 12.0 45.0 False 0.0 6.0 0.0 2.0 0.839307 n/a 2.0 10.0 0.850945 3.0 30.0 4.0 60.0 45.0 n/a 9.0 0.0 3.0 0 False 2.0 True 2.0 0.999447 1.11427 False n/a False False 3.0 False 1.1122 n/a 18.0 40.0 30.0 45.0 100.0 90.0 d 20.0 80.0 1.0 False 2.0 True 1.0 False 4.0 False 1.0 n/a False False 1.0 n/a n/a 0.95479 2.66667 0 9.0 0.0 n/a n/a n/a False 0.997244 False 1.0 2.5 0.290323 2.0 0 4.0 n/a 218 n/a 18.0 0.956572 7.24306 9.0 4.0 n/a 10.0 n/a False True False False n/a False 20.0 n/a 3.0 False
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| 49 |
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S48 30.0 0.507131 n/a n/a False -0.00956098 0.5 False 2.0 n/a 1.0 20.0 0.939729 2.77778 False True 0.0 0.733333 4.0 500.0 n/a 9.0 False 17.0 7.0 0.833333 20.0 10.0 40.0 False 0.0 10.0 0.0 3.0 0.824241 40.0 1.0 10.0 0.930168 3.0 30.0 5.0 65.0 43.0 n/a 9.0 0.0 2.0 0 False 4.0 True 4.0 0.996104 0.752623 False 20.0 False False 2.0 True 0.754819 n/a 10.0 20.0 15.0 30.0 50.0 70.0 d 15.0 50.0 4.0 False 0.0 True 0.0 False 4.0 False 1.0 0.917877 False False 1.0 15.0 7.0 0.943009 2.33333 lieux 16.0 0.0 52.0 n/a n/a False 0.96704 False 0.0 0.0 0.470588 1.0 Visages 4.0 70.0 168 n/a 5.0 0.9394 4.09028 7.0 5.0 50.0 13.0 30.0 False True True False 3.0 False 25.0 0.966885 2.0 False
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| 50 |
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| 51 |
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S50 60.0 0.801137 n/a n/a False -0.0291117 0.5 False 4.0 n/a 1.0 50.0 0.98375 1.66667 False True 0.5 0.666667 2.6 n/a n/a 9.0 False 12.0 10.0 0.666667 40.0 15.0 80.0 False 0.25 10.0 0.0 3.0 0.826063 60.0 0.0 10.0 0.954638 3.0 25.0 5.0 63.0 43.0 n/a 7.0 1.0 3.0 n/a False 4.0 True 3.0 0.991647 1.16622 False 30.0 False False 2.0 False 1.19242 n/a 20.0 50.0 30.0 70.0 80.0 95.0 u 27.0 100.0 4.0 False 0.0 True 1.0 False 4.0 False 0.0 n/a False False 1.0 8.0 12.5 0.933209 3.33333 visage 6.0 0.0 70.0 n/a n/a False 0.946907 False 1.0 1.5 0.25 1.0 n/a 3.0 150.0 117 n/a 4.0 0.941477 6.13889 4.0 3.0 75.0 10.0 250.0 False False True True 1.5 False 15.0 n/a 2.0 False
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| 52 |
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S51 120.0 0.902599 n/a n/a False -0.231889 4.0 False 3.0 n/a 2.0 10.0 0.752758 1.71429 False True 1.0 0.833333 2.6 700.0 n/a 7.0 False 9.5 7.0 0.833333 50.0 17.0 54.0 False 0.17 10.0 0.0 2.0 0.812932 30.0 2.0 10.0 0.520869 3.0 30.0 4.0 60.0 40.0 n/a 7.0 0.0 2.0 0 False 4.0 True 3.0 0.999712 1.25798 False 200.0 False False 2.0 False 1.34344 n/a 20.0 80.0 42.0 120.0 50.0 90.0 d 30.0 160.0 4.0 False 0.0 True 2.0 False 4.0 False 1.0 0.89375 False False 1.0 10.0 18.0 0.90344 2.66667 0 5.0 0.0 40.0 n/a n/a False 0.982427 False 1.0 1.5 0.263158 2.0 0 2.0 100.0 173 n/a 16.0 0.926512 5.69444 8.0 3.0 60.0 11.0 115.0 False True True False 2.0 False 12.0 1.1715 3.0 False
|
| 53 |
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S52 55.0 0.87824 n/a n/a False -0.00832569 2.0 False 5.0 n/a 1.0 20.0 0.971116 1.77778 True True 1.0 0.766667 2.6 400.0 n/a 9.0 False 12.5 7.0 0.5 35.0 10.0 75.0 False 0.0 8.0 0.0 2.0 1.0228 75.0 1.0 7.0 0.96279 3.0 25.0 4.0 61.0 42.0 n/a 9.0 0.0 1.0 0 False 4.0 True 1.0 0.997485 1.29562 False 150.0 False False 1.0 True 1.30718 n/a 12.0 30.0 25.0 80.0 80.0 100.0 u 25.0 90.0 3.0 False 0.0 True 2.0 False 4.0 False 2.0 0.855701 False False 1.0 20.0 12.0 1.16281 3.66667 0 7.0 2.0 60.0 0 n/a False 0.976732 False 1.0 2.0 0.28 2.0 Visages 3.0 100.0 206 n/a 10.0 1.1657 4.66667 4.0 5.0 60.0 10.0 15.0 False True False False 2.0 False 16.0 1.02892 2.0 False
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| 54 |
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S53 57.0 0.721953 1.0 1.0 False -0.038159 2.0 False 3.0 1.0 2.0 21.0 0.949123 2.0 False True 1.0 0.6 2.0 400.0 1.0 10.0 False 15.0 7.0 0.666667 18.0 8.0 47.0 False 0.5 10.0 0.0 2.0 1.04459 500.0 2.0 9.0 0.910964 3.0 25.0 4.0 53.0 34.0 1.0 8.0 0.0 3.0 "confusion entre ""p""et""b"",""a"" et""d"",""v""et""f"" a9ans pendant3-4mois " True 2.0 False 3.0 0.999318 1.09054 False 40.0 False False 2.0 False 1.07456 n/a 11.0 36.0 22.0 52.0 78.0 89.0 u 13.0 61.0 2.0 False 1.0 True 6.0 True 3.0 False 1.0 0.727899 False False 1.0 9.0 17.0 1.19193 0.0 n/a 10.0 0.0 40.0 0 n/a False 0.92573 True 1.0 1.5 0.333333 1.0 n/a 4.0 60.0 299 n/a 12.0 1.19054 6.53472 5.0 4.0 70.0 12.0 12.0 False True False False 1.8 False 20.0 1.04877 3.0 False
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| 55 |
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S54 38.0 0.383918 n/a 0.0 False -0.103711 1.0 False 3.0 n/a 3.0 5.0 0.86639 1.8 True True 1.0 0.666667 2.8 300.0 n/a 10.0 False 14.0 12.0 0.75 20.0 10.0 30.0 False 0.33 8.0 1.0 3.0 0.731965 10.0 1.0 9.0 0.76268 3.0 30.0 4.0 64.0 42.0 n/a 9.0 0.0 2.0 DYSORTHOGRAPHIE DYSLEXIE False 3.0 True 2.0 0.999901 0.594111 False 20.0 False False 2.0 False 0.571427 n/a 10.0 25.0 15.0 25.0 50.0 60.0 u 12.0 30.0 4.0 True 0.0 True 1.0 True 4.0 True 2.0 0.799681 False False 0.0 4.0 8.0 0.846727 3.0 noms 8.0 2.0 45.0 n/a n/a False 0.999775 True 1.0 1.5 0.285714 1.0 Visages 2.0 12.0 179 n/a 6.0 0.834232 4.625 12.0 2.0 40.0 10.0 50.0 False True True False 1.5 False 18.0 0.95225 3.0 False
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| 56 |
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S55 38.0 0.351037 n/a n/a False -0.0959172 2.5 False 2.0 n/a 2.0 15.0 0.874188 1.4 True True 2.0 0.53 2.6 500.0 n/a 10.0 False 12.0 8.0 0.5 19.0 9.0 25.0 False 0.0 10.0 0.0 2.0 0.670693 75.0 1.0 7.0 0.778271 3.0 28.0 4.0 75.0 45.0 n/a 5.0 1.0 3.0 0 False 3.0 True 1.0 0.997022 0.542072 False 35.0 False False 1.0 True 0.522487 n/a 13.0 27.0 20.0 39.0 45.0 57.0 d 15.0 29.0 4.0 False 0.0 True 2.0 False 3.0 False 1.0 0.969419 False False 1.0 10.0 13.0 0.771524 2.0 n/a 4.0 3.0 45.0 0 n/a False 1.03044 False 2.0 3.0 0.166667 3.0 LIEUX 2.0 50.0 297 n/a 13.0 0.764399 7.08333 6.0 1.0 55.0 10.0 75.0 False True True False 2.5 True 14.0 1.02732 2.0 False
|
| 57 |
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S56 50.0 0.728235 1.0 1.0 False -0.0200327 2.5 False 3.0 1.0 2.0 13.0 0.958526 1.55556 False False 1.0 0.7 3.0 450.0 1.0 9.0 False 11.5 9.0 0.666667 30.0 10.0 40.0 False 0.0 8.0 0.0 2.0 0.891965 35.0 2.0 9.0 0.938493 3.0 32.0 5.0 62.0 44.0 1.0 6.0 0.0 3.0 zozottement False 3.0 True 4.0 0.996171 1.08598 False 45.0 False False 2.0 False 1.08391 n/a 15.0 30.0 20.0 50.0 70.0 100.0 d 20.0 70.0 0.0 False 1.0 True 1.0 False 4.0 False 2.0 0.976141 True False 1.0 13.0 14.0 1.02026 2.66667 n/a 5.0 0.0 45.0 0 n/a False 0.966929 True 1.0 1.0 0.217391 1.0 visage 3.0 75.0 39 n/a 13.0 1.01659 6.15972 5.0 3.0 80.0 13.0 35.0 False True True True 3.0 False 14.0 0.967209 2.0 False
|
| 58 |
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S57 45.0 0.543197 n/a n/a False -0.036005 0.5 False 4.0 n/a 1.0 20.0 0.969654 2.0 False False 0.0 0.766667 2.4 700.0 n/a 9.0 False 13.5 6.5 0.583333 30.0 10.0 60.0 False 0.13 10.0 0.0 1.0 0.817328 30.0 1.0 10.0 0.933649 3.0 25.0 4.0 60.0 45.0 n/a 10.0 0.0 3.0 0 False 3.0 True 4.0 0.996329 0.804771 False 50.0 False False 2.0 False 0.8085 n/a 15.0 30.0 25.0 50.0 55.0 70.0 d 17.0 60.0 1.0 False 0.0 True 0.0 False 4.0 False 2.0 0.930744 False False 0.0 10.0 15.0 0.927787 2.33333 0 9.0 0.0 50.0 0 n/a False 0.98254 False 2.0 3.0 0.333333 2.0 visages, lieux 4.0 25.0 181 n/a 3.0 0.931521 7.61111 4.0 2.0 80.0 12.0 80.0 False True True False 1.2 False 18.0 1.14636 3.0 False
|
| 59 |
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S58 49.0 0.482002 n/a n/a False -0.0484288 1.5 False 5.0 n/a 1.0 10.0 0.95826 2.5 False False 1.0 0.933333 4.2 450.0 n/a 8.0 False 14.0 6.0 0.833333 30.0 10.0 50.0 False 0.2 9.0 0.0 4.0 0.770706 30.0 1.0 9.0 0.909831 3.0 35.0 4.0 62.0 45.0 n/a 9.0 0.0 3.0 0 False 4.0 True 4.0 0.997881 0.72737 False 50.0 False False 3.0 False 0.717416 n/a 15.0 30.0 20.0 50.0 55.0 65.0 u 20.0 50.0 4.0 False 0.0 True 4.0 False 5.0 False 1.0 0.950643 False True 1.0 14.0 12.0 0.880939 4.33333 0 12.0 0.0 50.0 0 n/a False 1.01537 False 1.0 3.0 0.428571 2.0 0 4.0 30.0 201 n/a 9.0 0.878385 8.06944 4.0 4.0 100.0 10.0 40.0 False True True False 2.5 False 20.0 1.01326 3.0 False
|
| 60 |
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S59 80.0 1.21402 n/a n/a False -0.0345568 0.0 False 3.0 n/a 1.0 15.0 0.975677 1.46154 False False 1.0 0.6 4.2 400.0 n/a 13.0 False 16.0 8.0 0.583333 40.0 10.0 100.0 False 0.0 8.0 0.0 4.0 1.14589 100.0 0.0 8.0 0.94112 3.0 35.0 5.0 60.0 40.0 n/a 4.0 0.0 3.0 0 False 4.0 True 3.0 0.992796 1.81669 False 50.0 False False 3.0 False 1.80695 n/a 15.0 40.0 30.0 100.0 100.0 150.0 d 20.0 100.0 3.0 False 0.0 True 1.0 False 3.0 False 1.0 0.748922 False False 0.0 20.0 100.0 1.30699 3.5 0 6.0 0.0 50.0 0 n/a False 0.956471 False 1.0 3.0 0.1875 3.0 0 3.5 60.0 203 n/a 2.0 1.30599 7.65278 n/a 4.0 100.0 15.0 30.0 False True True False 5.0 False 19.0 0.806267 2.0 False
|
| 61 |
+
S60 45.0 0.705189 1.0 1.0 False -0.0101898 0.0 False 3.0 1.0 1.0 7.0 0.974984 1.55556 False False 0.0 0.933333 3.6 380.0 1.0 9.0 False 11.5 8.5 0.416667 30.0 12.0 55.0 False 0.333333 10.0 0.0 3.0 0.828774 10.0 0.0 9.0 0.964794 3.0 30.0 5.0 64.0 45.0 1.0 10.0 0.0 2.0 n/a False 4.0 True 2.0 0.996178 1.04281 False 20.0 False n/a 3.0 False 1.04961 n/a 15.0 35.0 30.0 50.0 75.0 95.0 d 25.0 75.0 3.0 False 0.0 True 1.0 False 5.0 False 2.0 0.680142 False False 0.0 12.0 12.0 0.939798 3.0 lieux 5.0 0.0 50.0 0 n/a False 0.970066 False 0.0 2.5 0.217391 1.0 visage 3.0 40.0 132 n/a 0.0 0.944566 5.28472 7.0 5.0 50.0 12.0 10.0 False True True False 7.0 False 14.0 0.738193 2.0 False
|
| 62 |
+
S61 30.0 0.420859 n/a n/a False -0.0346947 1.0 False 3.0 n/a 3.0 17.5 0.946556 2.45455 False False 2.0 0.5 3.4 400.0 n/a 11.0 False 19.0 8.0 0.833333 20.0 10.0 30.0 False 0.666667 9.0 0.0 2.0 0.753665 100.0 1.0 8.0 0.911862 3.0 29.0 3.0 60.0 45.0 n/a 1.0 1.0 3.0 0 False 2.0 True 3.0 0.994075 0.603338 False 40.0 False False 1.0 False 0.626411 n/a 10.0 20.0 15.0 30.0 40.0 50.0 u 15.0 60.0 1.0 False 0.0 True 3.0 False 3.0 False 0.0 0.853415 False False 1.0 10.0 15.0 0.854203 2.5 physionomie 16.0 0.0 52.0 n/a n/a False 1.044 False 2.0 4.0 0.421053 2.0 lieux 3.0 25.0 199 n/a 10.0 0.858964 8.25694 9.0 3.0 50.0 11.0 200.0 False True False False 2.0 False 27.0 1.02602 3.0 False
|
| 63 |
+
S62 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a 367 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a
|
| 64 |
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|
| 65 |
+
S64 40.0 0.526118 n/a n/a False -0.000933116 4.0 False 4.0 n/a 1.0 50.0 0.971842 1.7 False False 2.0 0.4 2.4 600.0 0.0 10.0 False 13.5 7.0 0.75 20.0 10.0 40.0 False 0.75 8.0 1.0 3.0 0.88201 30.0 2.0 7.0 0.970909 3.0 36.0 5.0 60.0 40.0 n/a 4.0 0.0 3.0 0 False 2.0 True 1.0 0.991759 0.772525 False 10.0 False False 1.0 False 0.783079 n/a 10.0 25.0 15.0 50.0 50.0 60.0 u 15.0 60.0 1.0 True 0.0 True 3.0 False 4.0 False 2.0 0.726744 False False 1.0 3.0 20.0 1.00469 0.0 ESPECES ANIMALES 7.0 0.0 45.0 0 n/a True 0.958743 False 1.0 2.5 0.259259 2.0 VISAGE 1.0 40.0 296 n/a 18.0 1.00524 7.35417 5.0 1.0 50.0 12.0 20.0 False True False False 2.0 False 17.0 0.975383 3.0 False
|
| 66 |
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S65 30.0 0.422172 1.0 1.0 False -0.0217241 3.5 False 3.0 1.0 1.0 10.0 0.956833 1.58333 False False 2.0 0.866667 3.8 500.0 1.0 12.0 False 15.5 7.0 0.916667 20.0 10.0 40.0 False 0.0 10.0 0.0 4.0 0.757414 40.0 2.0 10.0 0.935109 3.0 30.0 5.0 64.0 43.0 1.0 8.0 0.0 3.0 0 False 3.0 True 4.0 0.996173 0.615527 False 60.0 False False 3.0 False 0.628364 n/a 10.0 30.0 20.0 30.0 40.0 60.0 d 15.0 50.0 4.0 False 0.0 True 1.0 False 4.0 False 1.0 0.939091 False False 1.0 30.0 12.0 0.853278 2.0 n/a 7.0 0.0 55.0 0 n/a False 0.964347 False 1.0 2.5 0.225806 2.0 n/a 4.0 70.0 327 n/a 17.0 0.863237 8.05556 4.0 4.0 80.0 10.0 40.0 False True False False 3.0 False 19.0 0.994149 3.0 False
|
| 67 |
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S66 50.0 0.602292 n/a n/a False -0.0338606 1.5 False 4.0 n/a 1.0 20.0 0.934056 2.11111 False False 0.0 0.6 3.2 400.0 n/a 9.0 False 14.0 9.0 0.5 15.0 7.0 35.0 False 0.0 10.0 0.0 3.0 1.0295 25.0 1.0 9.0 0.900195 3.0 25.0 3.0 65.0 42.0 n/a 8.0 0.0 3.0 0 False 4.0 True 3.0 0.992627 0.904788 False 35.0 False False 3.0 False 0.896458 n/a 10.0 30.0 15.0 50.0 50.0 80.0 u 10.0 50.0 4.0 False 0.0 True 1.0 False 5.0 False 2.0 0.894138 False False 1.0 20.0 15.0 1.17632 0.0 n/a 10.0 0.0 50.0 0 n/a False 1.03726 False 2.0 3.0 0.357143 1.0 VISAGES LIEUX 3.0 90.0 344 n/a 7.0 1.17333 7.27083 5.0 3.0 80.0 12.0 20.0 False True False True 2.0 False 19.0 0.942724 2.0 False
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| 68 |
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S67 50.0 0.760311 n/a n/a False -0.090743 0.5 False 3.0 n/a 2.0 40.0 0.957141 1.75 False False 0.0 0.7 2.8 300.0 n/a 8.0 False 11.0 7.0 0.166667 40.0 12.0 60.0 False 0.25 8.0 0.0 2.0 0.895573 50.0 0.0 10.0 0.866398 3.0 32.0 5.0 65.0 44.0 2.0 5.0 0.0 3.0 0 False 3.0 True 2.0 0.996432 1.11832 False 150.0 False False 2.0 True 1.13165 n/a 15.0 45.0 25.0 100.0 70.0 90.0 u 25.0 80.0 3.0 False 0.0 True 2.0 False 5.0 False 1.0 0.719087 False False 1.0 3.0 12.0 1.01291 2.33333 0 6.0 0.0 58.0 Chiffres, voyelles en couleur n/a False 0.975137 False 2.0 3.0 0.272727 1.0 Lieux, itineraires 2.0 40.0 215 n/a 3.0 1.0207 6.49306 5.0 2.0 80.0 10.0 8.0 False True True False 2.0 False 14.0 1.00441 1.0 False
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| 69 |
+
S68 42.0 0.518261 n/a n/a False -0.0204349 2.0 False 5.0 n/a 1.0 5.0 0.936235 1.88889 False False 1.0 1.0 4.2 700.0 n/a 9.0 False 13.0 7.0 0.833333 27.0 12.0 47.0 False 0.666667 10.0 1.0 3.0 0.753259 15.0 1.0 10.0 0.9158 3.0 33.0 4.0 63.0 43.0 n/a 10.0 0.0 3.0 n/a False 4.0 True 5.0 0.999161 0.76944 False 50.0 True False 3.0 False 0.771384 n/a 12.0 27.0 23.0 32.0 58.0 72.0 u 21.0 59.0 1.0 True 0.0 True 0.0 False 5.0 False 1.0 0.850019 False False 1.0 8.0 15.0 0.858164 4.0 n/a 8.0 0.0 40.0 0 n/a False 1.00769 False 2.0 4.0 0.307692 1.0 lieux 5.0 50.0 94 n/a 10.0 0.858501 8.90278 6.0 5.0 60.0 16.0 130.0 False True False False 3.0 False 17.0 1.08324 3.0 False
|
| 70 |
+
S69 40.0 0.320483 n/a n/a False -0.0823311 4.0 False 4.0 n/a 1.0 32.5 0.906829 2.14286 False False 2.0 0.7 4.2 450.0 n/a 7.0 False 11.0 9.0 0.5 20.0 13.0 40.0 False 0.0 7.0 0.0 4.0 0.601481 150.0 2.0 9.0 0.824498 3.0 25.0 5.0 60.0 48.0 n/a 8.0 0.0 3.0 n/a False 4.0 True 4.0 0.989427 0.488542 False 2500.0 False False 2.0 True 0.47701 n/a 12.0 30.0 25.0 40.0 45.0 50.0 u 20.0 35.0 4.0 False 0.0 True 3.0 False 5.0 False 2.0 0.554342 False False 1.0 8.0 15.0 0.68626 4.0 n/a 8.0 0.0 35.0 couleur, mot, espace n/a False 0.95227 False 2.0 4.0 0.363636 2.0 visage, lieux 4.0 200.0 105 n/a 18.0 0.685518 9.0 4.0 5.0 70.0 13.0 10.0 False True False False 2.5 False 15.0 1.11756 3.0 False
|
| 71 |
+
S70 350.0 4.37116 n/a n/a False -0.082708 3.0 False 4.0 n/a 1.0 15.0 0.923019 1.5 False False 2.0 0.766667 3.8 500.0 n/a 10.0 False 12.5 9.0 0.833333 50.0 15.0 250.0 False 0.0 8.0 0.0 3.0 1.71511 20.0 2.0 10.0 0.840311 3.0 25.0 4.0 68.0 43.0 n/a 8.0 0.0 3.0 0 False 4.0 True 4.0 0.995391 6.66643 False 200.0 False False 3.0 False 6.50608 n/a 15.0 100.0 30.0 200.0 400.0 500.0 d 20.0 300.0 2.0 False 0.0 True 1.0 False 5.0 False 2.0 0.832625 False False 1.0 5.0 6.0 1.97093 3.33333 0 5.0 0.0 40.0 Odeurs, images : souvenirs n/a False 0.998561 False 0.0 3.0 0.2 1.0 Visages 5.0 70.0 187 n/a 16.0 1.95474 8.42361 5.0 5.0 40.0 14.0 50.0 False True True False 3.0 False 15.0 1.0604 4.0 False
|
| 72 |
+
S71 20.0 0.212617 n/a n/a False -0.0629865 1.5 False n/a n/a 2.0 15.0 0.830302 1.55556 False False 0.0 0.5 3.2 400.0 n/a 9.0 False 11.5 8.0 0.5 15.0 10.0 20.0 False 0.0 6.0 0.0 n/a 0.516706 40.0 1.0 7.0 0.767316 3.0 25.0 4.0 60.0 42.0 n/a 3.0 0.0 3.0 0 False 3.0 True 2.0 0.997657 0.325419 False 50.0 False False 2.0 False 0.316461 n/a 10.0 20.0 15.0 20.0 30.0 40.0 u 10.0 20.0 1.0 False 0.0 True 2.0 False n/a False 2.0 0.968262 False False 1.0 15.0 10.0 0.594702 n/a 0 5.0 0.0 50.0 n/a n/a False 0.97386 False 1.0 3.0 0.217391 1.0 Visages 2.0 60.0 159 n/a 7.0 0.588898 7.16667 6.0 3.0 100.0 10.0 100.0 False True True False 2.0 False 14.0 1.05611 3.0 False
|
| 73 |
+
S72 60.0 0.715723 1.0 1.0 False -0.0551373 2.0 False 2.0 2.0 1.0 40.0 0.958627 1.33333 True True 1.0 0.433333 3.6 450.0 1.0 15.0 False 17.5 7.0 0.416667 30.0 10.0 70.0 False 0.0 8.0 2.0 0.0 1.0041 30.0 1.0 7.0 0.90349 3.0 21.0 3.0 67.0 45.0 1.0 5.0 0.0 3.0 pbl de deglutition a9ans(suce son pouce) False 3.0 True 3.0 0.98314 1.07017 False 50.0 False False 1.0 False 1.06529 n/a 10.0 30.0 20.0 70.0 70.0 80.0 d 20.0 70.0 2.0 True 0.0 True 2.0 False 3.0 False 0.0 0.830847 False False 1.0 20.0 14.0 1.14585 0.0 PHYSIONOMIE 5.0 3.0 60.0 0 n/a True 1.03714 True 1.0 2.5 0.142857 1.0 ESPECES VEGETALES 3.0 110.0 329 n/a 10.0 1.14439 6.59722 8.0 2.0 50.0 10.0 20.0 False True True False 5.0 True 20.0 0.841678 2.0 True
|
| 74 |
+
S73 40.0 0.927448 1.0 1.0 False -0.00182578 n/a False n/a 1.0 3.0 15.0 0.979823 1.90476 False False n/a 0.766667 3.2 300.0 0.0 8.4 False 12.2 8.0 0.916667 25.0 10.0 50.0 False 0.0 9.0 0.0 n/a 1.07666 60.0 n/a 10.0 0.977997 3.0 30.0 3.0 63.0 41.0 1.0 10.0 0.0 3.0 n/a n/a 2.0 True 4.0 0.994564 1.36044 False 70.0 False False n/a False 1.38042 n/a 10.0 30.0 20.0 70.0 80.0 110.0 n/a 18.0 90.0 4.0 False 0.0 True 3.0 False n/a False 2.0 0.979557 False False n/a 15.0 13.0 1.22344 n/a espece animal 7.6 0.0 60.0 n/a n/a False 1.0435 False 1.0 1.0 0.311475 1.0 visage 3.0 60.0 365 n/a n/a 1.22709 n/a 7.0 3.0 50.0 10.0 55.0 False True n/a False 3.0 False 16.0 0.929294 3.0 False
|
| 75 |
+
S74 30.0 0.382676 n/a n/a False -0.0665277 2.5 True 4.0 n/a 1.0 40.0 0.920906 1.66667 False True 1.0 0.8 3.6 250.0 n/a 9.0 False 12.0 12.0 0.833333 30.0 12.0 50.0 False 0.2 9.0 1.0 3.0 0.637316 20.0 1.0 10.0 0.854378 3.0 32.0 4.0 62.0 42.0 n/a 7.0 0.0 3.0 EXPRESSION ORALE False 4.0 True 5.0 0.999392 0.562843 False 30.0 False False 3.0 False 0.569578 n/a 15.0 30.0 20.0 50.0 50.0 50.0 U? 25.0 50.0 1.0 True 2.0 True 3.0 True 4.0 False 2.0 0.859567 False False 1.0 10.0 10.0 0.720039 3.5 lieux 6.0 2.0 60.0 0 n/a False 0.999466 True 0.0 0.0 0.25 1.0 Visages 5.0 50.0 207 n/a 11.0 0.726359 5.81944 4.0 5.0 50.0 10.0 30.0 False True True False 2.5 True 15.0 0.819761 3.0 False
|
| 76 |
+
S75 90.0 1.17674 1.0 1.0 False -0.0322937 1.5 False 4.0 1.0 1.0 30.0 0.962962 1.5 False False 1.0 0.966667 5.0 300.0 1.0 10.0 False 12.5 7.0 0.666667 40.0 10.0 80.0 False 0.2 10.0 0.0 5.0 1.06134 15.0 1.0 10.0 0.930669 3.0 32.0 4.0 64.0 43.0 1.0 10.0 0.0 3.0 0 False 3.0 True 3.0 0.999677 1.77613 False 40.0 False False 3.0 False 1.75148 n/a 20.0 50.0 30.0 80.0 120.0 150.0 u 25.0 100.0 3.0 False 0.0 True 1.0 False 5.0 False 2.0 0.843897 False False 0.0 7.0 10.0 1.2123 4.0 n/a 5.0 0.0 60.0 0 n/a False 1.00794 False 2.0 3.5 0.2 2.0 LIEUX VISAGES 3.0 60.0 319 n/a 7.0 1.20962 7.72222 6.0 5.0 70.0 13.0 120.0 False True True True 3.0 False 15.0 0.945441 2.0 False
|
| 77 |
+
S76 50.0 0.611865 n/a n/a False -0.0818007 3.5 False 4.0 n/a 1.0 20.0 0.921049 1.66667 False False 2.0 0.833333 2.6 500.0 n/a 9.0 False 12.0 7.0 0.25 30.0 10.0 35.0 False 0.0 10.0 0.0 3.0 0.873615 150.0 2.0 10.0 0.839249 3.0 33.0 4.0 66.0 45.0 n/a 6.0 0.0 3.0 0 False 4.0 True 3.0 0.999685 0.93416 False 200.0 False False 2.0 True 0.910705 n/a 10.0 30.0 20.0 40.0 70.0 90.0 u 20.0 50.0 3.0 False 0.0 True 3.0 False 3.0 False 2.0 0.825401 False True 1.0 50.0 15.0 1.0031 3.33333 0 6.0 0.0 30.0 Couleur / mots n/a False 1.02149 False 2.0 3.5 0.25 2.0 visages, lieux 3.0 200.0 172 n/a 17.0 0.995672 7.95833 6.0 3.0 65.0 10.0 100.0 False True False False 2.0 False 15.0 1.09488 3.0 False
|
| 78 |
+
S77 45.0 0.689299 n/a n/a False -0.0180914 1.0 False 5.0 n/a 2.0 10.0 0.968552 2.11111 True True 0.0 0.966667 3.0 500.0 n/a 9.0 False 14.0 11.0 0.416667 20.0 10.0 40.0 False 0.0 9.0 0.0 4.0 0.981267 15.0 1.0 10.0 0.950461 3.0 30.0 4.0 64.0 43.0 n/a 10.0 n/a 3.0 n/a False 4.0 True 3.0 0.999983 1.01458 False 500.0 False False 3.0 False 1.02596 n/a 10.0 30.0 20.0 70.0 60.0 80.0 u 15.0 70.0 2.0 False 1.0 True 3.0 False 5.0 False 2.0 0.671399 False False 1.0 7.0 10.0 1.11533 4.33333 lieux 10.0 3.0 60.0 0 n/a False 1.00274 False 1.0 0.0 0.357143 2.0 visage 4.0 700.0 115 n/a 6.0 1.11837 4.65972 5.0 4.0 80.0 15.0 20.0 False True True False 2.0 True 19.0 1.19359 2.0 False
|
| 79 |
+
S78 40.0 0.548867 n/a n/a False -0.0193456 3.0 False 4.0 n/a 2.0 25.0 0.950317 1.7 False False 2.0 0.7 3.8 600.0 n/a 10.0 False 13.5 15.0 0.916667 40.0 10.0 50.0 False 0.0 10.0 0.0 3.0 0.813199 60.0 1.0 10.0 0.930971 3.0 30.0 4.0 62.0 41.0 1.0 7.0 2.0 3.0 0 False 2.0 True 3.0 0.999859 0.815318 False 45.0 False False 2.0 False 0.816939 n/a 15.0 30.0 20.0 60.0 60.0 70.0 u 20.0 60.0 2.0 False 0.0 True 2.0 False 4.0 False 2.0 0.905331 False False 1.0 10.0 15.0 0.925195 2.0 n/a 7.0 0.0 50.0 0 n/a False 0.991229 False 1.0 2.5 0.259259 1.0 VISAGES 1.0 30.0 328 n/a 14.0 0.926816 6.74306 9.0 2.0 60.0 16.0 112.0 False True False False 3.0 False 17.0 0.960007 n/a False
|
| 80 |
+
S79 42.0 0.449873 n/a 0.0 False 0.00970278 4.0 False 3.0 n/a 1.0 12.0 0.905277 1.4 False False 2.0 0.566667 1.8 350.0 n/a 10.0 False 12.0 7.0 0.666667 28.0 16.0 30.0 False 0.25 9.0 0.0 1.0 0.603731 30.0 2.0 9.0 0.914979 3.0 27.0 4.0 68.0 45.0 n/a 6.0 0.0 3.0 0 False 4.0 True 1.0 0.997786 0.671734 False 100.0 False True 1.0 False 0.669595 n/a 18.0 28.0 21.0 50.0 59.0 63.0 d 22.0 55.0 3.0 False 0.0 True 3.0 True 5.0 False 1.0 0.917245 False False 1.0 20.0 12.0 0.693804 1.66667 Mettre nom sur un visage 4.0 0.0 70.0 Chiffres ds espace n/a False 1.01049 False 1.0 3.5 0.166667 3.0 tout 1.0 80.0 198 n/a 18.0 0.688082 8.22222 4.0 1.0 50.0 12.0 100.0 False False False False 2.0 False 14.0 1.03246 3.0 False
|
| 81 |
+
S80 48.0 0.634019 n/a n/a False -0.00810036 2.5 False 4.0 n/a 2.0 30.0 0.948885 1.5 False True 1.0 0.733333 2.6 530.0 n/a 10.0 False 12.5 13.0 0.5 31.0 8.0 41.0 False 0.0 7.0 0.0 2.0 0.91701 250.0 0.0 10.0 0.940784 3.0 25.0 4.0 62.0 43.0 n/a 10.0 0.0 3.0 0 False 3.0 True 3.0 0.996996 0.946805 False 20.0 False False 2.0 False 0.94368 n/a 12.0 35.0 34.0 56.0 68.0 86.0 u 19.0 63.0 2.0 False 1.0 True 1.0 False 5.0 False 2.0 0.798489 False False 1.0 6.0 18.0 1.03757 3.33333 0 5.0 0.0 62.0 0 n/a False 0.982516 False 2.0 2.0 0.2 1.0 visages, lieux 3.0 45.0 180 n/a 9.0 1.04513 6.375 8.0 3.0 75.0 10.0 50.0 False True True False 3.0 False 15.0 0.987773 3.0 False
|
| 82 |
+
S81 n/a n/a n/a n/a False n/a n/a False n/a n/a n/a 15.0 n/a n/a n/a n/a n/a n/a n/a 500.0 n/a n/a False n/a 8.0 n/a n/a n/a n/a False n/a n/a n/a n/a n/a 40.0 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a False 40.0 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a 1.0 0.979913 False n/a n/a 10.0 15.0 n/a n/a n/a n/a n/a 55.0 n/a n/a n/a n/a n/a 1.0 n/a n/a n/a n/a n/a 50.0 217 n/a n/a n/a n/a n/a n/a 90.0 n/a 60.0 n/a n/a n/a n/a 3.0 n/a n/a 1.00486 n/a False
|
| 83 |
+
S82 55.0 0.611077 n/a n/a False -0.0475203 3.5 False 3.0 n/a 1.0 15.0 0.963192 2.0 True True 1.0 0.85 2.4 1000.0 n/a 10.0 False 15.0 8.0 0.583333 25.0 11.0 45.0 False 0.33 10.0 0.0 3.0 0.877608 15.0 2.0 10.0 0.915672 3.0 30.0 3.0 66.0 43.0 n/a 7.0 0.0 1.0 0 False 3.0 True 3.0 0.994773 0.92664 False 25.0 False False 2.0 False 0.909533 n/a 12.0 30.0 20.0 50.0 68.0 80.0 u 17.0 55.0 2.0 False 0.0 True 2.0 False 4.0 False 2.0 0.745845 False False 1.0 8.0 12.0 1.0073 3.0 lieux 10.0 2.0 50.0 0 n/a False 1.05757 False 0.0 2.0 0.333333 2.0 Visages 3.0 20.0 195 n/a 15.0 1.00022 5.27778 4.0 4.0 50.0 13.0 6.0 False True False False 2.0 False 20.0 1.00696 2.0 False
|
| 84 |
+
S83 55.0 0.752174 n/a n/a False -0.0102645 3.0 False 3.0 n/a 1.0 7.0 0.983114 1.25 False True 1.0 1.0 3.4 600.0 n/a 12.0 False 13.5 8.0 0.75 30.0 10.0 60.0 False 0.0 10.0 0.0 3.0 0.946814 15.0 2.0 10.0 0.972849 3.0 35.0 3.0 65.0 43.0 n/a 10.0 0.0 3.0 0 False 3.0 True 4.0 0.992436 1.10866 False 100.0 False False 3.0 False 1.11954 n/a 13.0 40.0 25.0 75.0 70.0 90.0 d 25.0 80.0 4.0 False 0.0 True 1.0 False 4.0 False 2.0 0.777745 False False 1.0 8.0 12.0 1.07195 2.66667 lieux 3.0 0.0 50.0 0 n/a False 1.06735 False 0.0 1.0 0.111111 3.0 Visages 4.0 30.0 184 n/a 14.0 1.0791 6.4375 5.0 4.0 60.0 11.0 50.0 False True False False 8.0 False 15.0 0.904109 3.0 False
|
| 85 |
+
S84 70.0 0.918418 n/a n/a False 0.053325 1.0 False 4.0 n/a 1.0 7.0 0.888236 1.54545 False False 1.0 0.8 3.4 450.0 n/a 11.0 False 14.0 11.0 0.75 40.0 12.0 75.0 False 0.25 10.0 0.0 3.0 1.15816 80.0 1.0 10.0 0.941561 3.0 33.0 5.0 63.0 42.0 n/a 9.0 0.0 3.0 0 False 4.0 True 3.0 0.995588 1.37754 False 70.0 False False 3.0 False 1.36698 n/a 5.0 40.0 35.0 70.0 95.0 110.0 d 20.0 85.0 4.0 False 0.0 True 0.0 False 4.0 False 2.0 0.818761 False False 1.0 5.0 14.0 1.3146 3.33333 0 6.0 0.0 45.0 0 n/a False 0.966338 False 2.0 2.5 0.214286 2.0 visages, lieux 3.0 25.0 193 n/a 8.0 1.31998 7.10417 5.0 3.0 60.0 10.0 9.0 False True True False 1.5 False 17.0 1.05465 2.0 False
|
| 86 |
+
S85 25.0 0.278677 n/a n/a False -0.022051 3.0 False 4.0 n/a 2.0 20.0 0.94183 2.0 False False 1.0 0.6 4.0 500.0 0.0 9.0 False 13.5 9.0 0.833333 25.0 10.0 30.0 False 0.33 8.0 0.0 2.0 0.562786 60.0 2.0 9.0 0.919779 3.0 30.0 5.0 60.0 40.0 n/a 9.0 0.0 3.0 0 False 3.0 True 3.0 0.995747 0.400515 False 80.0 False False 2.0 False 0.414786 n/a 15.0 25.0 20.0 30.0 35.0 40.0 u 15.0 45.0 4.0 False 0.0 True 3.0 False 4.0 False 2.0 0.962147 False False 1.0 10.0 12.0 0.631332 3.0 animaux 9.0 0.0 65.0 0 n/a False 0.944038 False 1.0 n/a 0.333333 2.0 Visages 3.0 50.0 169 n/a 14.0 0.641416 5.56944 6.0 4.0 60.0 13.0 30.0 False True n/a False 2.0 False 18.0 1.04717 4.0 False
|
| 87 |
+
S86 40.0 0.780401 1.0 1.0 False -0.0458562 1.5 False 4.0 1.0 1.0 50.0 0.878883 1.75 False True 0.0 0.5 3.4 750.0 1.0 10.0 False 13.75 9.0 0.416667 40.0 12.0 90.0 True 0.0 9.0 3.0 3.0 0.993049 90.0 2.0 10.0 0.833027 3.0 32.0 4.0 63.0 45.0 1.0 6.0 0.0 3.0 dyslexie, confusion che/jeu, f/v False 4.0 True 4.0 0.999649 1.14484 True 30.0 False False 2.0 False 1.16156 n/a 10.0 20.0 28.0 70.0 65.0 90.0 u 15.0 80.0 4.0 True 0.0 True 2.0 True 4.0 True 1.0 0.89167 False False 1.0 12.0 11.0 1.13006 0.0 n/a 7.5 0.0 60.0 0 n/a False 1.01092 True 1.0 1.5 0.272727 1.0 n/a 2.0 80.0 346 n/a 9.0 1.13179 6.26389 6.0 4.0 70.0 13.0 30.0 False True n/a True 2.5 False 17.5 1.04276 3.0 False
|
| 88 |
+
S87 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a 369 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a
|
| 89 |
+
S88 45.0 0.525943 n/a 0.0 False -0.0442923 0.0 False 4.0 n/a 1.0 35.0 0.958444 1.875 False False 0.0 0.6 3.6 500.0 n/a 8.0 True 11.5 10.0 0.75 25.0 10.0 40.0 False 0.5 8.0 2.0 2.0 0.825556 60.0 1.0 10.0 0.914152 3.0 32.0 5.0 60.0 42.0 n/a 8.0 0.0 3.0 APPRENTISSAGE LECTURE, math False 3.0 True 3.0 0.995658 0.77895 False 100.0 True True 1.0 False 0.782818 n/a 15.0 35.0 20.0 60.0 60.0 60.0 d 15.0 60.0 3.0 True 1.0 True 0.0 False 3.0 False 2.0 0.860257 False True 0.0 20.0 15.0 0.93793 2.33333 noms 7.0 0.0 60.0 nombre / espace, gouts et sons n/a False 0.955381 True 2.0 3.0 0.304348 1.0 visages, lieux 1.0 150.0 178 n/a 2.0 0.940899 7.375 4.0 1.0 80.0 10.0 400.0 False True True False 3.0 False 15.0 1.05283 2.0 False
|
| 90 |
+
S89 70.0 1.09973 n/a n/a False -0.0425949 1.0 False 5.0 n/a 3.0 40.0 0.927972 2.55556 False True 0.0 0.666667 3.0 200.0 n/a 9.0 False 16.0 20.0 0.583333 40.0 11.0 60.0 False 0.0 10.0 0.0 3.0 1.01285 150.0 0.0 10.0 0.885377 3.0 24.0 3.0 62.0 38.0 n/a 7.0 0.0 2.0 0 True 4.0 True 3.0 0.992471 1.64304 False 40.0 False False 3.0 False 1.63685 n/a 15.0 30.0 25.0 50.0 100.0 150.0 d 25.0 100.0 2.0 False 0.0 True 1.0 False 5.0 False 2.0 0.00909366 False True 0.0 15.0 10.0 1.16136 4.0 LIEUX 14.0 0.0 5.0 0 n/a False 1.01316 False 0.0 0.0 0.4375 1.0 VISAGE 5.0 1000.0 289 n/a 2.0 1.15436 3.38194 9.0 3.0 50.0 18.0 300.0 False True True False 1000.0 False 23.0 0.126279 2.0 False
|
| 91 |
+
S90 80.0 1.19538 n/a n/a False -0.00869327 3.0 False 2.0 n/a 3.0 15.0 0.894658 1.71429 False False 2.0 0.7 2.8 400.0 n/a 7.0 False 9.5 7.0 0.666667 60.0 10.0 40.0 False 0.33 10.0 1.0 1.0 1.11558 20.0 2.0 10.0 0.885965 3.0 22.0 5.0 62.0 45.0 n/a 7.0 0.0 3.0 en histoire False 4.0 True 2.0 0.983444 1.75143 False 30.0 True False 1.0 False 1.77922 n/a 15.0 60.0 30.0 80.0 100.0 150.0 d 15.0 130.0 2.0 True 1.0 True 0.0 False 4.0 False 1.0 0.905508 False False 1.0 8.0 10.0 1.26396 1.66667 lieux 5.0 0.0 60.0 n/a n/a False 0.939536 False 0.0 1.5 0.263158 1.0 0 3.0 20.0 213 n/a 16.0 1.27144 5.84722 10.0 2.0 80.0 10.0 30.0 False True True False 2.5 False 12.0 0.953995 2.0 False
|
| 92 |
+
S91 50.0 0.611427 1.0 1.0 False -0.00681096 3.5 False 3.0 1.0 2.0 20.0 0.966239 1.6 False False 2.0 0.9 4.2 500.0 1.0 10.0 False 13.0 7.0 0.833333 20.0 10.0 50.0 False 0.0 10.0 0.0 3.0 0.920033 40.0 2.0 10.0 0.959428 3.0 23.0 5.0 61.0 43.0 1.0 10.0 0.0 3.0 deglutition a 15ans pendant 4mois False 4.0 True 4.0 0.987777 0.899697 False 120.0 False False 2.0 False 0.910054 n/a 10.0 30.0 20.0 50.0 60.0 70.0 u 20.0 70.0 2.0 False 0.0 True 1.0 False 4.0 False 1.0 n/a False False 1.0 15.0 10.0 1.04483 2.0 n/a 6.0 0.0 60.0 0 n/a False 0.934578 True 2.0 3.0 0.230769 2.0 LIEUX 4.0 60.0 334 n/a 17.0 1.04858 8.25694 7.0 3.0 n/a 10.0 140.0 False True False True 2.0 False 16.0 n/a 4.0 False
|
| 93 |
+
S92 38.0 0.475912 n/a n/a False -0.0850252 1.5 False 5.0 n/a 1.0 6.0 0.785702 1.44444 False True 1.0 0.8 3.2 500.0 n/a 9.0 False 11.0 9.0 0.75 25.0 12.0 29.0 False 0.0 10.0 0.0 3.0 0.696258 120.0 1.0 9.0 0.700677 3.0 32.0 5.0 65.0 43.0 n/a 8.0 2.0 3.0 0 False 4.0 True 4.0 0.99624 0.744678 False 200.0 False False 3.0 False 0.708352 n/a 15.0 25.0 24.0 44.0 66.0 77.0 u 12.0 29.0 4.0 False 0.0 True n/a False 5.0 False 1.0 0.815552 False True 1.0 15.0 12.0 0.810939 3.66667 0 4.0 0.0 52.0 Suites ds espaCe et couleurs n/a False 0.972245 False 1.0 2.0 0.181818 2.0 0 5.0 20.0 196 n/a 9.0 0.793536 6.95833 6.0 5.0 80.0 10.0 50.0 False True False False 3.0 False 13.0 1.04952 3.0 False
|
| 94 |
+
S93 50.0 0.717351 n/a 0.0 False -0.0384674 3.5 False 3.0 n/a 1.0 20.0 0.959921 2.08333 False False 1.0 1.0 4.8 280.0 n/a 12.0 False 18.5 8.0 0.916667 40.0 12.0 70.0 False 0.0 10.0 0.0 3.0 0.856346 30.0 1.0 10.0 0.921454 3.0 35.0 4.0 60.0 43.0 n/a 10.0 0.0 3.0 0 False 3.0 True 4.0 0.997048 1.0501 False 30.0 False False 3.0 False 1.06771 n/a 15.0 40.0 30.0 50.0 60.0 100.0 d 20.0 80.0 4.0 False 0.0 True 1.0 False 4.0 False 1.0 0.907422 False False 1.0 10.0 12.0 0.967146 3.0 NOMS 13.0 0.0 50.0 NUM DE TELEPHONE n/a False 1.00396 False 2.0 3.0 0.351351 1.0 LIEUX CHIFFRES 4.0 120.0 343 n/a 13.0 0.975992 8.03472 5.0 5.0 50.0 12.0 100.0 False True n/a False 2.0 False 25.0 0.980029 2.0 False
|
| 95 |
+
S94 53.0 0.913518 n/a n/a False -0.0127455 4.0 False 3.0 n/a 1.0 17.0 0.992355 2.1 False False 1.0 0.9 4.7 250.0 n/a 10.0 False 15.5 6.5 1.0 30.0 10.0 60.0 False 0.0 9.0 0.0 3.0 1.03356 50.0 2.0 10.0 0.97961 3.0 36.0 5.0 64.0 43.0 n/a 9.0 0.0 3.0 0 False 1.0 True 5.0 0.994238 1.35131 False 65.0 False False 3.0 False 1.35969 n/a 13.0 38.0 25.0 60.0 90.0 110.0 d 18.0 90.0 4.0 False 0.0 True 5.0 False 4.0 False 1.0 0.937513 False False 1.0 15.0 15.0 1.17454 3.33333 0 11.0 0.0 50.0 nombre / espace n/a False 0.979051 False 1.0 4.0 0.354839 3.0 0 4.0 55.0 189 n/a 16.0 1.17797 9.66667 4.0 4.0 60.0 10.0 120.0 False True n/a False 2.75 False 21.0 0.933082 4.0 False
|
phenotype/subject.tsv
ADDED
|
@@ -0,0 +1,95 @@
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| 1 |
+
participant_id localizer_short_easy protocol scanner family motor_error laterality site sex schizophrenic id dyslexic father comments tr excluded basic localizer_long_complex type sound_problem epi_problem statistics_spm5 exam localizer_short_complex anatomy dyscalculic language localizer_long_easy age video_problem synaesthete mother acquisition
|
| 2 |
+
S01 n/a UNICOG 3 F01 n/a Right handed SHFJ M n/a 404 n/a 0 Localizer not done n/a n/a True n/a Basic n/a n/a n/a S01 n/a n/a n/a French n/a 24 n/a n/a 0 0
|
| 3 |
+
S02 False UNICOG 3 F02 n/a Right handed SHFJ M n/a 191 n/a 0 son a 50% audible pour les histoires 2.4 False True False Basic True n/a True S02 True n/a n/a French False 20 n/a n/a 0 1
|
| 4 |
+
S03 False UNICOG 3 F03 n/a Right handed SHFJ F n/a 228 n/a 0 n/a 2.4 False True False Basic False n/a True S03 True n/a n/a French False 22 n/a n/a 0 1
|
| 5 |
+
S04 False UNICOG 3 F04 False Right handed Neurospin M n/a 320 n/a 0 Substractions difficulties 2.4 False True False Basic False n/a True S04 True Ok n/a French False 20 True n/a 0 1
|
| 6 |
+
S05 False UNICOG 3 F05 False Right handed Neurospin F n/a 341 n/a 0 Substractions were difficult for him/her 2.4 n/a True False Basic False n/a n/a S05 True Ok n/a French False 23 False n/a 0 1
|
| 7 |
+
S06 False UNICOG 3 F06 True Right handed Neurospin M n/a 311 n/a 0 n/a 2.4 False True False Basic False n/a True S06 True Ok n/a French False 19 True n/a 0 1
|
| 8 |
+
S07 False UNICOG 3 F07 True Right handed Neurospin F n/a 316 n/a 0 Substractions difficulties, pushing mistake 1 time 2.4 False True False Basic False n/a True S07 True Ok n/a French False 26 True n/a 0 1
|
| 9 |
+
S08 False UNICOG 3 F89 True Right handed Neurospin M n/a 347 n/a 0 Rare pushing mistakes 2.4 n/a True False Basic False n/a n/a S08 True Ok n/a French False 27 False n/a 0 1
|
| 10 |
+
S09 False UNICOG 3 F09 False Right handed Neurospin F n/a 326 n/a 0 Right side more activated in audio contrast 2.4 False True False Basic False n/a n/a S09 True Ok n/a French False 21 False n/a 0 1
|
| 11 |
+
S10 False UNICOG 3 F10 n/a Right handed SHFJ F n/a 176 n/a 0 n/a 2.4 False True False Basic False n/a True S10 True n/a n/a French False 24 n/a n/a 0 1
|
| 12 |
+
S11 False UNICOG 3 F11 n/a Right handed SHFJ F n/a 193 n/a 0 son trop bas, plusieurs pharses inaudibles 2.4 False True False Basic True n/a True S11 True n/a n/a French False 47 n/a True 0 1
|
| 13 |
+
S12 False UNICOG 3 F12 n/a Right handed SHFJ F n/a 201 n/a 0 n/a 2.4 False True False Basic False n/a True S12 True n/a n/a French False 23 n/a n/a 0 1
|
| 14 |
+
S13 False UNICOG 3 F13 False Right handed Neurospin M n/a 365 n/a 0 n/a 2.4 True True False Basic False n/a True S13 True Ok n/a French False 19 False n/a 0 1
|
| 15 |
+
S14 False UNICOG 3 F14 n/a Right handed SHFJ F n/a 247 n/a 0 n/a 2.4 False True False Basic False n/a True S14 True n/a n/a French False 21 n/a n/a 0 1
|
| 16 |
+
S15 False UNICOG 3 F15 n/a Right handed SHFJ F n/a 11 n/a 0 6 sessions+seq.Fovea 2.4 False True False Basic n/a n/a True S15 True ok n/a French False 22 n/a n/a 0 1
|
| 17 |
+
S16 False UNICOG 3 F16 n/a Right handed SHFJ F n/a 218 n/a 0 n/a 2.4 False True False Basic False n/a True S16 True n/a n/a French False 24 n/a n/a 0 1
|
| 18 |
+
S17 n/a UNICOG 3 F17 n/a Right handed SHFJ M n/a 351 n/a 0 Localizer not done n/a n/a True n/a Basic n/a n/a n/a S17 n/a n/a n/a French n/a 22 n/a n/a 0 0
|
| 19 |
+
S18 False UNICOG 3 F18 True Right handed Neurospin F n/a 310 n/a 0 Sound too high, substractions difficulties, pushing errors 2.4 False True False Basic True n/a True S18 True Ok n/a French False 20 True n/a 0 1
|
| 20 |
+
S19 False UNICOG 3 F52 n/a Right handed SHFJ M n/a 204 n/a 0 n/a 2.4 False True False Basic False n/a True S19 True n/a n/a French False 18 n/a n/a 0 1
|
| 21 |
+
S20 False UNICOG 3 F20 n/a Right handed SHFJ F n/a 179 n/a 0 n/a 2.4 False True False Basic False n/a True S20 True n/a n/a French False 25 n/a n/a 0 1
|
| 22 |
+
S21 False UNICOG 3 F21 n/a Right handed SHFJ M n/a 150 n/a 0 meme que S21 et <sanitized> 2.4 False True False Basic n/a n/a True S21 True n/a n/a French False 21 n/a n/a 0 3
|
| 23 |
+
S22 False UNICOG 3 F22 n/a Right handed SHFJ M n/a 209 n/a 0 n/a 2.4 False True False Basic False n/a True S22 True n/a n/a French False 40 n/a n/a 0 1
|
| 24 |
+
S23 False UNICOG 3 F23 False Right handed Neurospin F n/a 334 n/a 0 Substrations difficulties 2.4 False True False Basic False n/a n/a S23 True Ok n/a French False 24 True n/a 0 1
|
| 25 |
+
S24 False UNICOG 3 F24 False Right handed Neurospin F n/a 323 n/a 0 n/a 2.4 False True False Basic False n/a n/a S24 True Ok n/a French False 18 False n/a 0 1
|
| 26 |
+
S25 False UNICOG 3 F25 n/a Right handed SHFJ F n/a 202 n/a 0 meme que S25 2.4 False True False Basic False n/a True S25 True n/a n/a French False 24 n/a n/a 0 2
|
| 27 |
+
S26 False UNICOG 3 F26 False Right handed Neurospin F n/a 349 n/a 0 Some substraction errors. Voxel size (localizer) : 2x2x3 mm^3 2.4 n/a True False Basic False n/a True S26 True axial+artefacts n/a French False 24 True n/a 0 1
|
| 28 |
+
S27 False UNICOG 3 F27 False Right handed Neurospin M n/a 330 n/a 0 n/a 2.4 False True False Basic False n/a n/a S27 True Ok n/a French False 30 False n/a 0 1
|
| 29 |
+
S28 False UNICOG 3 F28 True Right handed Neurospin F n/a 345 n/a 0 Pushing mistakes 3 times 2.4 n/a True False Basic False n/a n/a S28 True Ok n/a French False 18 False n/a 0 1
|
| 30 |
+
S29 False UNICOG 3 F29 False Right handed Neurospin F n/a 339 n/a 0 Weak activation in Checkboard contrast 2.4 False True False Basic False n/a n/a S29 True Ok n/a French False 21 False n/a 0 1
|
| 31 |
+
S30 False UNICOG 3 F30 n/a Right handed SHFJ F n/a 194 n/a 0 n/a 2.4 False True False Basic False n/a True S30 True n/a n/a French False 34 n/a n/a 0 1
|
| 32 |
+
S31 False UNICOG 3 F31 False Right handed Neurospin F n/a 344 n/a 0 n/a 2.4 n/a True False Basic False n/a n/a S31 True Ok n/a French False 22 False n/a 0 1
|
| 33 |
+
S32 False UNICOG 3 F32 n/a Right handed SHFJ F n/a 206 n/a 0 n/a 2.4 False True False Basic False n/a True S32 True n/a n/a French False 26 n/a n/a 0 1
|
| 34 |
+
S33 False UNICOG 3 F33 n/a Right handed SHFJ F n/a 240 n/a 0 n/a 2.4 False True False Basic False n/a True S33 True n/a n/a French False 21 n/a n/a 0 1
|
| 35 |
+
S34 False UNICOG 3 F34 n/a Right handed SHFJ M n/a 214 n/a 0 n/a 2.4 False True False Basic False n/a True S34 True n/a n/a French False 21 n/a n/a 0 1
|
| 36 |
+
S35 False UNICOG 3 F35 n/a Right handed SHFJ F n/a 246 n/a 0 meme que S35 - reglage shim mauvais selon Antoinette 2.4 False True False Basic False True True S35 True n/a n/a French False 24 n/a n/a 0 2
|
| 37 |
+
S36 False UNICOG 3 F36 n/a Right handed SHFJ F n/a 224 n/a 0 n/a 2.4 False True False Basic False n/a True S36 True n/a n/a French False 25 n/a n/a 0 1
|
| 38 |
+
S37 False UNICOG 3 F37 False Right handed Neurospin M n/a 362 n/a 0 n/a 2.4 False True False Basic False False True S37 True Ok n/a French False 22 False n/a 0 1
|
| 39 |
+
S38 False UNICOG 3 F38 n/a Right handed SHFJ M n/a 213 n/a 0 n/a 2.4 False True False Basic False n/a True S38 True n/a n/a French False n/a n/a n/a 0 1
|
| 40 |
+
S39 False UNICOG 3 F39 n/a Right handed SHFJ M n/a 243 n/a 0 meme que S39 2.4 False True False Basic False n/a True S39 True n/a n/a French False 22 n/a n/a 0 2
|
| 41 |
+
S40 False UNICOG 3 F40 n/a Right handed SHFJ F n/a 221 n/a 0 n/a 2.4 False True False Basic False n/a True S40 True n/a n/a French False 24 n/a True 0 1
|
| 42 |
+
S41 False UNICOG 3 F41 n/a Right handed Neurospin M n/a 738 n/a 0 n/a 2.4 n/a True False Basic n/a n/a True S41 True n/a n/a French False 18 n/a n/a 0 4
|
| 43 |
+
S42 False UNICOG 3 F42 False Right handed Neurospin M n/a 318 n/a 0 Problemes de normalisation des images (centre des images trop loin de l'axe CA-CP). Resolu a la main 2.4 False True False Basic False n/a True S42 True Ok n/a French False 26 False n/a 0 1
|
| 44 |
+
S43 False UNICOG 3 F43 False Right handed Neurospin M n/a 358 n/a 0 Sound problems (head phones). Voxel size (localizer) : 2x2x3 mm^3 2.4 n/a True False Basic True n/a True S43 True n/a n/a French False 49 False n/a 0 1
|
| 45 |
+
S44 False UNICOG 3 F44 n/a Right handed SHFJ F n/a 203 n/a 0 meme que <sanitized> 2.4 False True False Basic False n/a True S44 True n/a n/a French False 34 n/a n/a 0 2
|
| 46 |
+
S45 False UNICOG 3 F45 n/a Right handed SHFJ M n/a 184 n/a 0 n/a 2.4 False True False Basic False n/a True S45 True n/a n/a French False 21 n/a n/a 0 1
|
| 47 |
+
S46 False UNICOG 3 F46 False Right handed Neurospin F n/a 315 n/a 0 n/a 2.4 False True False Basic False n/a True S46 True Ok n/a French False 24 False n/a 0 1
|
| 48 |
+
S47 False UNICOG 3 F47 n/a Right handed SHFJ M n/a 244 n/a 0 n/a 2.4 False True False Basic False n/a True S47 True n/a n/a French False 19 n/a n/a 0 1
|
| 49 |
+
S48 False UNICOG 3 F48 n/a Right handed SHFJ F n/a 182 n/a 0 n/a 2.4 False True False Basic False n/a True S48 True n/a n/a French False 21 n/a n/a 0 1
|
| 50 |
+
S49 False UNICOG 3 F49 n/a Right handed SHFJ F n/a 186 n/a 0 n/a 2.4 False True False Basic False n/a True S49 True n/a n/a French False 22 n/a n/a 0 1
|
| 51 |
+
S50 False UNICOG 3 F50 n/a Right handed SHFJ F n/a 352 n/a 0 Localizer not done 2.4 n/a True False Basic n/a n/a n/a S50 False n/a n/a French False 32 n/a n/a 0 2
|
| 52 |
+
S51 False UNICOG 3 F51 n/a Right handed SHFJ M n/a 189 n/a 0 son trop bas, plusieurs pharses inaudibles 2.4 False True False Basic True n/a True S51 True n/a n/a French False 30 n/a n/a 0 1
|
| 53 |
+
S52 False UNICOG 3 F52 n/a Right handed SHFJ F n/a 230 n/a 0 anat avec un echo lumineux 2.4 False True False Basic False n/a True S52 True n/a n/a French False 22 n/a n/a 0 1
|
| 54 |
+
S53 False UNICOG 3 F53 False Right handed Neurospin F n/a 340 n/a 0 Little difficulty to read the sentences ? 2.4 n/a True False Basic False n/a True S53 True Ok n/a French False 18 False n/a 0 1
|
| 55 |
+
S54 False UNICOG 3 F54 n/a Right handed SHFJ F n/a 197 n/a 0 n/a 2.4 False True False Basic False n/a True S54 True n/a n/a French False 20 n/a n/a 0 1
|
| 56 |
+
S55 False UNICOG 3 F55 False Right handed Neurospin F n/a 342 n/a 0 Substractions were difficult for him/her 2.4 n/a True False Basic False n/a n/a S55 True Ok n/a French False 21 False n/a 0 1
|
| 57 |
+
S56 False UNICOG 3 F56 False Right handed Neurospin M n/a 336 n/a 0 Acquisition of anatomy in axial (pilote, the rest are in sagittal) 2.4 False True False Basic False n/a n/a S56 True Ok n/a French False 23 True n/a 0 4
|
| 58 |
+
S57 False UNICOG 3 F57 n/a Right handed SHFJ F n/a 199 n/a 0 n/a 2.4 False True False Basic False n/a True S57 True n/a n/a French False 20 n/a n/a 0 1
|
| 59 |
+
S58 False UNICOG 3 F58 n/a Right handed SHFJ M n/a 225 n/a 0 n/a 2.4 False True False Basic False n/a True S58 True n/a n/a French False 34 n/a n/a 0 1
|
| 60 |
+
S59 False UNICOG 3 F59 n/a Right handed SHFJ M n/a 227 n/a 0 n/a 2.4 False True False Basic False n/a True S59 True n/a n/a French False 30 n/a n/a 0 1
|
| 61 |
+
S60 n/a UNICOG 3 F60 n/a Right handed Neurospin M n/a 357 n/a 0 Localizer not done n/a n/a True n/a Basic n/a n/a n/a S60 n/a n/a n/a French n/a 21 n/a n/a 0 0
|
| 62 |
+
S61 False UNICOG 3 F61 n/a Right handed SHFJ M n/a 223 n/a 0 n/a 2.4 False True False Basic False n/a True S61 True n/a n/a French False 23 n/a n/a 0 1
|
| 63 |
+
S62 False UNICOG 3 F62 n/a Right handed SHFJ F n/a 211 n/a 0 n/a 2.4 False True False Basic False n/a True S62 True n/a n/a French False n/a n/a True 0 1
|
| 64 |
+
S63 False UNICOG 3 F63 True Right handed Neurospin F n/a 312 n/a 0 Pushing mistakes 2 or 3 times 2.4 False True False Basic False n/a True S63 True Ok n/a French False 19 False n/a 0 1
|
| 65 |
+
S64 False UNICOG 3 F64 False Right handed Neurospin F n/a 343 n/a 0 Substractions were difficult for him/her 2.4 n/a True False Basic False n/a n/a S64 True Ok n/a French False 21 False n/a 0 1
|
| 66 |
+
S65 False UNICOG 3 F65 True Right handed Neurospin M n/a 314 n/a 0 Pushing mistakes 3 times 2.4 False True False Basic False n/a True S65 True Ok n/a French False 19 False n/a 0 1
|
| 67 |
+
S66 False UNICOG 3 F66 True Right handed Neurospin M n/a 366 n/a 0 Pushing mistakes 1 or 2 times. Voxel size (localizer) : 2x2x2 mm^3 2.4 n/a True False Basic False n/a True S66 True axial+artefacts n/a French False 26 False n/a 0 1
|
| 68 |
+
S67 False UNICOG 3 F67 n/a Right handed SHFJ F n/a 239 n/a 0 n/a 2.4 False True False Basic False n/a True S67 True n/a n/a French False 44 n/a True 0 1
|
| 69 |
+
S68 False UNICOG 3 F68 n/a Right handed SHFJ M n/a 245 n/a 0 meme que S68 2.4 False True False Basic False n/a True S68 True n/a n/a French False 20 n/a n/a 0 3
|
| 70 |
+
S69 n/a UNICOG 3 F69 n/a Right handed SHFJ F n/a 353 n/a 0 Localizer not done n/a n/a True n/a Basic n/a n/a n/a S69 n/a n/a n/a French n/a 21 n/a n/a 0 0
|
| 71 |
+
S70 False UNICOG 3 F59 n/a Right handed SHFJ M n/a 208 n/a 0 n/a 2.4 False True False Basic False n/a True S70 True n/a n/a French False 25 n/a n/a 0 1
|
| 72 |
+
S71 False UNICOG 3 F71 n/a Right handed SHFJ M n/a 185 n/a 0 meme que <sanitized> 2.4 False True False Basic False n/a True S71 True n/a n/a French False 21 n/a n/a 0 2
|
| 73 |
+
S72 False UNICOG 3 F72 False Right handed Neurospin F n/a 325 n/a 0 n/a 2.4 False True False Basic False n/a n/a S72 True Ok n/a French False 37 False n/a 0 1
|
| 74 |
+
S73 False UNICOG 3 F73 False Right handed Neurospin M n/a 348 n/a 0 n/a 2.4 n/a True False Basic False n/a n/a S73 True Ok n/a French False 19 False n/a 0 1
|
| 75 |
+
S74 False UNICOG 3 F74 n/a Right handed SHFJ M n/a 231 n/a 0 anat pourris mais existe au 1.5T 2.4 False True False Basic False n/a True S74 True n/a n/a French False 21 n/a n/a 0 1
|
| 76 |
+
S75 False UNICOG 3 F75 False Right handed Neurospin M n/a 328 n/a 0 n/a 2.4 False True False Basic False n/a True S75 True Ok n/a French False 20 False n/a 0 1
|
| 77 |
+
S76 False UNICOG 3 F76 n/a Right handed SHFJ F n/a 187 n/a 0 n/a 2.4 False True False Basic False n/a True S76 True n/a n/a French False 28 n/a n/a 0 1
|
| 78 |
+
S77 False UNICOG 3 F77 n/a Right handed SHFJ F n/a 120 n/a 0 n/a 2.4 False True False Basic False n/a True S77 True n/a n/a French False 23 n/a n/a 0 1
|
| 79 |
+
S78 False UNICOG 3 F78 False Right handed Neurospin M n/a 321 n/a 0 n/a 2.4 False True False Basic False n/a True S78 True Ok n/a French False 29 False n/a 0 1
|
| 80 |
+
S79 False UNICOG 3 F79 n/a Right handed SHFJ F n/a 222 n/a 0 n/a 2.4 False True False Basic False n/a True S79 True n/a n/a French False 43 n/a True 0 1
|
| 81 |
+
S80 False UNICOG 3 F80 n/a Right handed SHFJ F n/a 198 n/a 0 n/a 2.4 False True False Basic False n/a True S80 True n/a n/a French False 19 n/a n/a 0 1
|
| 82 |
+
S81 False UNICOG 3 F81 n/a Right handed SHFJ M n/a 241 n/a 0 n/a 2.4 False True False Basic False n/a True S81 True n/a n/a French False n/a n/a n/a 0 1
|
| 83 |
+
S82 False UNICOG 3 F82 n/a Right handed SHFJ F n/a 219 n/a 0 n/a 2.4 False True False Basic False n/a True S82 True n/a n/a French False 20 n/a n/a 0 1
|
| 84 |
+
S83 False UNICOG 3 F83 False Right handed Neurospin F n/a 331 n/a 0 n/a 2.4 False True False Basic False n/a n/a S83 True Ok n/a French False 20 False n/a 0 2
|
| 85 |
+
S84 False UNICOG 3 F84 n/a Right handed SHFJ F n/a 217 n/a 0 n/a 2.4 False True False Basic False n/a True S84 True n/a n/a French False 23 n/a n/a 0 1
|
| 86 |
+
S85 False UNICOG 3 F85 n/a Right handed SHFJ M n/a 183 n/a 0 n/a 2.4 False True False Basic False n/a True S85 True n/a n/a French False 21 n/a n/a 0 1
|
| 87 |
+
S86 False UNICOG 3 F86 False Right handed Neurospin M n/a 370 n/a 0 Some substraction errors. Voxel size (localizer) : 2x2x2 mm^3 2.4 n/a True False Basic False n/a True S86 True axial+artefacts n/a French False 31 True n/a 0 1
|
| 88 |
+
S87 False UNICOG 3 F87 n/a Right handed SHFJ M n/a 216 n/a 0 n/a 2.4 False True False Basic False n/a True S87 True n/a n/a French False n/a n/a n/a 0 1
|
| 89 |
+
S88 False UNICOG 3 F88 n/a Right handed SHFJ M n/a 196 n/a 0 n/a 2.4 False True False Basic False n/a True S88 True n/a n/a French False 19 n/a True 0 1
|
| 90 |
+
S89 False UNICOG 3 F89 True Right handed Neurospin M n/a 346 n/a 0 Rare pushing mistakes 2.4 n/a True False Basic False n/a n/a S89 True Ok n/a French False 29 False n/a 0 1
|
| 91 |
+
S90 False UNICOG 3 F90 n/a Right handed SHFJ M n/a 237 n/a 0 n/a 2.4 False True False Basic False n/a True S90 True n/a n/a French False 21 n/a n/a 0 1
|
| 92 |
+
S91 False UNICOG 3 F91 False Right handed Neurospin M n/a 338 n/a 0 n/a 2.4 False True False Basic False n/a n/a S91 True Ok n/a French False 23 False n/a 0 1
|
| 93 |
+
S92 False UNICOG 3 F92 n/a Right handed SHFJ F n/a 220 n/a 0 n/a 2.4 False True False Basic False n/a True S92 True n/a n/a French False 26 n/a True 0 1
|
| 94 |
+
S93 False UNICOG 3 F93 False Right handed Neurospin M n/a 332 n/a 0 Acquisition of anatomy in axial (pilote, the rest are in sagittal) 2.4 False True False Basic False n/a n/a S93 True Ok n/a French False 36 False n/a 0 1
|
| 95 |
+
S94 False UNICOG 3 F94 n/a Right handed SHFJ M n/a 210 n/a 0 n/a 2.4 False True False Basic False n/a True S94 True n/a n/a French False 41 n/a True 0 1
|
sub-S01/.DS_Store
ADDED
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Binary file (6.15 kB). View file
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sub-S02/func/sub-S02_task-localizer_events.tsv
ADDED
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221.4 1 video_computation
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257.4 1 audio_left_hand
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260.4 1 video_computation
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264.0 1 vertical_checkerboard
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266.7 1 horizontal_checkerboard
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269.7 1 horizontal_checkerboard
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275.4 1 video_right_hand
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278.4 1 vertical_checkerboard
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| 77 |
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284.4 1 audio_sentence
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288.0 1 video_sentence
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291.0 1 video_right_hand
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| 80 |
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293.4 1 audio_sentence
|
| 81 |
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296.7 1 audio_sentence
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sub-S03/func/sub-S03_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
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159.0 1 video_sentence
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234.0 1 video_computation
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| 65 |
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236.7 1 audio_sentence
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246.0 1 video_sentence
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251.7 1 audio_computation
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| 69 |
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254.7 1 audio_left_hand
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257.4 1 audio_left_hand
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| 71 |
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260.4 1 video_computation
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| 72 |
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264.0 1 vertical_checkerboard
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266.7 1 horizontal_checkerboard
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269.7 1 horizontal_checkerboard
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275.4 1 video_right_hand
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278.4 1 vertical_checkerboard
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| 79 |
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291.0 1 video_right_hand
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| 80 |
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293.4 1 audio_sentence
|
| 81 |
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296.7 1 audio_sentence
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sub-S04/func/sub-S04_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
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| 1 |
+
onset duration trial_type
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| 2 |
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|
| 3 |
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| 19 |
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87.0 1 audio_right_hand
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96.0 1 vertical_checkerboard
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108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
+
143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
+
156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
+
162.0 1 audio_right_hand
|
| 44 |
+
164.4 1 video_computation
|
| 45 |
+
167.7 1 video_sentence
|
| 46 |
+
170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
+
191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S05/func/sub-S05_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
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|
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|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
+
2.4 1 video_computation
|
| 4 |
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8.7 1 horizontal_checkerboard
|
| 5 |
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11.4 1 audio_right_hand
|
| 6 |
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15.0 1 audio_sentence
|
| 7 |
+
18.0 1 video_right_hand
|
| 8 |
+
20.7 1 audio_sentence
|
| 9 |
+
23.7 1 audio_left_hand
|
| 10 |
+
26.7 1 video_left_hand
|
| 11 |
+
29.7 1 audio_sentence
|
| 12 |
+
33.0 1 vertical_checkerboard
|
| 13 |
+
35.4 1 audio_computation
|
| 14 |
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39.0 1 video_sentence
|
| 15 |
+
41.7 1 video_sentence
|
| 16 |
+
44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
+
69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
+
75.0 1 video_sentence
|
| 24 |
+
83.4 1 audio_computation
|
| 25 |
+
87.0 1 audio_right_hand
|
| 26 |
+
89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
+
143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
+
156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
+
162.0 1 audio_right_hand
|
| 44 |
+
164.4 1 video_computation
|
| 45 |
+
167.7 1 video_sentence
|
| 46 |
+
170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
+
191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S10/func/sub-S10_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
|
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|
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|
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|
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|
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|
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|
|
|
|
|
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|
|
|
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|
|
|
|
|
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|
|
|
|
|
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|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
+
2.4 1 video_computation
|
| 4 |
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8.7 1 horizontal_checkerboard
|
| 5 |
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11.4 1 audio_right_hand
|
| 6 |
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15.0 1 audio_sentence
|
| 7 |
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18.0 1 video_right_hand
|
| 8 |
+
20.7 1 audio_sentence
|
| 9 |
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23.7 1 audio_left_hand
|
| 10 |
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26.7 1 video_left_hand
|
| 11 |
+
29.7 1 audio_sentence
|
| 12 |
+
33.0 1 vertical_checkerboard
|
| 13 |
+
35.4 1 audio_computation
|
| 14 |
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39.0 1 video_sentence
|
| 15 |
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41.7 1 video_sentence
|
| 16 |
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44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
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69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
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75.0 1 video_sentence
|
| 24 |
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83.4 1 audio_computation
|
| 25 |
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87.0 1 audio_right_hand
|
| 26 |
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89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
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131.4 1 video_sentence
|
| 34 |
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135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
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143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
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156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
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162.0 1 audio_right_hand
|
| 44 |
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164.4 1 video_computation
|
| 45 |
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167.7 1 video_sentence
|
| 46 |
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170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
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191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
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224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S11/func/sub-S11_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
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|
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|
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|
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|
|
|
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|
|
|
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|
|
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|
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|
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|
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|
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|
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|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
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|
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|
|
|
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|
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|
|
|
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|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
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2.4 1 video_computation
|
| 4 |
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8.7 1 horizontal_checkerboard
|
| 5 |
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11.4 1 audio_right_hand
|
| 6 |
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15.0 1 audio_sentence
|
| 7 |
+
18.0 1 video_right_hand
|
| 8 |
+
20.7 1 audio_sentence
|
| 9 |
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23.7 1 audio_left_hand
|
| 10 |
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26.7 1 video_left_hand
|
| 11 |
+
29.7 1 audio_sentence
|
| 12 |
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33.0 1 vertical_checkerboard
|
| 13 |
+
35.4 1 audio_computation
|
| 14 |
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39.0 1 video_sentence
|
| 15 |
+
41.7 1 video_sentence
|
| 16 |
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44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
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69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
+
75.0 1 video_sentence
|
| 24 |
+
83.4 1 audio_computation
|
| 25 |
+
87.0 1 audio_right_hand
|
| 26 |
+
89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
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122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
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143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
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149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
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156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
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162.0 1 audio_right_hand
|
| 44 |
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164.4 1 video_computation
|
| 45 |
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167.7 1 video_sentence
|
| 46 |
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170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
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176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
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191.7 1 audio_computation
|
| 51 |
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195.0 1 video_sentence
|
| 52 |
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198.0 1 video_computation
|
| 53 |
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201.0 1 video_computation
|
| 54 |
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203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
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210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
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218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S12/func/sub-S12_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
+
2.4 1 video_computation
|
| 4 |
+
8.7 1 horizontal_checkerboard
|
| 5 |
+
11.4 1 audio_right_hand
|
| 6 |
+
15.0 1 audio_sentence
|
| 7 |
+
18.0 1 video_right_hand
|
| 8 |
+
20.7 1 audio_sentence
|
| 9 |
+
23.7 1 audio_left_hand
|
| 10 |
+
26.7 1 video_left_hand
|
| 11 |
+
29.7 1 audio_sentence
|
| 12 |
+
33.0 1 vertical_checkerboard
|
| 13 |
+
35.4 1 audio_computation
|
| 14 |
+
39.0 1 video_sentence
|
| 15 |
+
41.7 1 video_sentence
|
| 16 |
+
44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
+
69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
+
75.0 1 video_sentence
|
| 24 |
+
83.4 1 audio_computation
|
| 25 |
+
87.0 1 audio_right_hand
|
| 26 |
+
89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
+
143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
+
156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
+
162.0 1 audio_right_hand
|
| 44 |
+
164.4 1 video_computation
|
| 45 |
+
167.7 1 video_sentence
|
| 46 |
+
170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
+
191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S13/func/sub-S13_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
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|
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|
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|
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|
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|
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|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
+
2.4 1 video_computation
|
| 4 |
+
8.7 1 horizontal_checkerboard
|
| 5 |
+
11.4 1 audio_right_hand
|
| 6 |
+
15.0 1 audio_sentence
|
| 7 |
+
18.0 1 video_right_hand
|
| 8 |
+
20.7 1 audio_sentence
|
| 9 |
+
23.7 1 audio_left_hand
|
| 10 |
+
26.7 1 video_left_hand
|
| 11 |
+
29.7 1 audio_sentence
|
| 12 |
+
33.0 1 vertical_checkerboard
|
| 13 |
+
35.4 1 audio_computation
|
| 14 |
+
39.0 1 video_sentence
|
| 15 |
+
41.7 1 video_sentence
|
| 16 |
+
44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
+
69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
+
75.0 1 video_sentence
|
| 24 |
+
83.4 1 audio_computation
|
| 25 |
+
87.0 1 audio_right_hand
|
| 26 |
+
89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
+
143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
+
156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
+
162.0 1 audio_right_hand
|
| 44 |
+
164.4 1 video_computation
|
| 45 |
+
167.7 1 video_sentence
|
| 46 |
+
170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
+
191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S14/func/sub-S14_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
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|
|
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|
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|
|
|
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|
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|
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|
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|
|
|
|
|
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|
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|
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|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
+
2.4 1 video_computation
|
| 4 |
+
8.7 1 horizontal_checkerboard
|
| 5 |
+
11.4 1 audio_right_hand
|
| 6 |
+
15.0 1 audio_sentence
|
| 7 |
+
18.0 1 video_right_hand
|
| 8 |
+
20.7 1 audio_sentence
|
| 9 |
+
23.7 1 audio_left_hand
|
| 10 |
+
26.7 1 video_left_hand
|
| 11 |
+
29.7 1 audio_sentence
|
| 12 |
+
33.0 1 vertical_checkerboard
|
| 13 |
+
35.4 1 audio_computation
|
| 14 |
+
39.0 1 video_sentence
|
| 15 |
+
41.7 1 video_sentence
|
| 16 |
+
44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
+
69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
+
75.0 1 video_sentence
|
| 24 |
+
83.4 1 audio_computation
|
| 25 |
+
87.0 1 audio_right_hand
|
| 26 |
+
89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
+
143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
+
156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
+
162.0 1 audio_right_hand
|
| 44 |
+
164.4 1 video_computation
|
| 45 |
+
167.7 1 video_sentence
|
| 46 |
+
170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
+
191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S15/func/sub-S15_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
|
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|
|
|
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|
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|
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|
|
|
|
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|
|
|
|
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|
|
|
|
|
|
|
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|
|
|
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|
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|
|
|
|
|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
+
2.4 1 video_computation
|
| 4 |
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8.7 1 horizontal_checkerboard
|
| 5 |
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11.4 1 audio_right_hand
|
| 6 |
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15.0 1 audio_sentence
|
| 7 |
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18.0 1 video_right_hand
|
| 8 |
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20.7 1 audio_sentence
|
| 9 |
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23.7 1 audio_left_hand
|
| 10 |
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26.7 1 video_left_hand
|
| 11 |
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29.7 1 audio_sentence
|
| 12 |
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33.0 1 vertical_checkerboard
|
| 13 |
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35.4 1 audio_computation
|
| 14 |
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39.0 1 video_sentence
|
| 15 |
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41.7 1 video_sentence
|
| 16 |
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44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
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69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
+
75.0 1 video_sentence
|
| 24 |
+
83.4 1 audio_computation
|
| 25 |
+
87.0 1 audio_right_hand
|
| 26 |
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89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
+
143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
+
156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
+
162.0 1 audio_right_hand
|
| 44 |
+
164.4 1 video_computation
|
| 45 |
+
167.7 1 video_sentence
|
| 46 |
+
170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
+
191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S16/func/sub-S16_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
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|
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|
|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
|
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|
|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
+
2.4 1 video_computation
|
| 4 |
+
8.7 1 horizontal_checkerboard
|
| 5 |
+
11.4 1 audio_right_hand
|
| 6 |
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15.0 1 audio_sentence
|
| 7 |
+
18.0 1 video_right_hand
|
| 8 |
+
20.7 1 audio_sentence
|
| 9 |
+
23.7 1 audio_left_hand
|
| 10 |
+
26.7 1 video_left_hand
|
| 11 |
+
29.7 1 audio_sentence
|
| 12 |
+
33.0 1 vertical_checkerboard
|
| 13 |
+
35.4 1 audio_computation
|
| 14 |
+
39.0 1 video_sentence
|
| 15 |
+
41.7 1 video_sentence
|
| 16 |
+
44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
+
69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
+
75.0 1 video_sentence
|
| 24 |
+
83.4 1 audio_computation
|
| 25 |
+
87.0 1 audio_right_hand
|
| 26 |
+
89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
+
143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
+
156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
+
162.0 1 audio_right_hand
|
| 44 |
+
164.4 1 video_computation
|
| 45 |
+
167.7 1 video_sentence
|
| 46 |
+
170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
+
191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S17/func/sub-S17_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
+
2.4 1 video_computation
|
| 4 |
+
8.7 1 horizontal_checkerboard
|
| 5 |
+
11.4 1 audio_right_hand
|
| 6 |
+
15.0 1 audio_sentence
|
| 7 |
+
18.0 1 video_right_hand
|
| 8 |
+
20.7 1 audio_sentence
|
| 9 |
+
23.7 1 audio_left_hand
|
| 10 |
+
26.7 1 video_left_hand
|
| 11 |
+
29.7 1 audio_sentence
|
| 12 |
+
33.0 1 vertical_checkerboard
|
| 13 |
+
35.4 1 audio_computation
|
| 14 |
+
39.0 1 video_sentence
|
| 15 |
+
41.7 1 video_sentence
|
| 16 |
+
44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
+
69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
+
75.0 1 video_sentence
|
| 24 |
+
83.4 1 audio_computation
|
| 25 |
+
87.0 1 audio_right_hand
|
| 26 |
+
89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
+
143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
+
156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
+
162.0 1 audio_right_hand
|
| 44 |
+
164.4 1 video_computation
|
| 45 |
+
167.7 1 video_sentence
|
| 46 |
+
170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
+
191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S18/func/sub-S18_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
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|
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|
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|
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|
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|
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|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
+
2.4 1 video_computation
|
| 4 |
+
8.7 1 horizontal_checkerboard
|
| 5 |
+
11.4 1 audio_right_hand
|
| 6 |
+
15.0 1 audio_sentence
|
| 7 |
+
18.0 1 video_right_hand
|
| 8 |
+
20.7 1 audio_sentence
|
| 9 |
+
23.7 1 audio_left_hand
|
| 10 |
+
26.7 1 video_left_hand
|
| 11 |
+
29.7 1 audio_sentence
|
| 12 |
+
33.0 1 vertical_checkerboard
|
| 13 |
+
35.4 1 audio_computation
|
| 14 |
+
39.0 1 video_sentence
|
| 15 |
+
41.7 1 video_sentence
|
| 16 |
+
44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
+
69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
+
75.0 1 video_sentence
|
| 24 |
+
83.4 1 audio_computation
|
| 25 |
+
87.0 1 audio_right_hand
|
| 26 |
+
89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
+
143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
+
156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
+
162.0 1 audio_right_hand
|
| 44 |
+
164.4 1 video_computation
|
| 45 |
+
167.7 1 video_sentence
|
| 46 |
+
170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
+
191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S19/func/sub-S19_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
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|
|
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|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
|
|
|
|
|
|
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|
|
|
|
|
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|
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|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
+
2.4 1 video_computation
|
| 4 |
+
8.7 1 horizontal_checkerboard
|
| 5 |
+
11.4 1 audio_right_hand
|
| 6 |
+
15.0 1 audio_sentence
|
| 7 |
+
18.0 1 video_right_hand
|
| 8 |
+
20.7 1 audio_sentence
|
| 9 |
+
23.7 1 audio_left_hand
|
| 10 |
+
26.7 1 video_left_hand
|
| 11 |
+
29.7 1 audio_sentence
|
| 12 |
+
33.0 1 vertical_checkerboard
|
| 13 |
+
35.4 1 audio_computation
|
| 14 |
+
39.0 1 video_sentence
|
| 15 |
+
41.7 1 video_sentence
|
| 16 |
+
44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
+
69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
+
75.0 1 video_sentence
|
| 24 |
+
83.4 1 audio_computation
|
| 25 |
+
87.0 1 audio_right_hand
|
| 26 |
+
89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
+
143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
+
156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
+
162.0 1 audio_right_hand
|
| 44 |
+
164.4 1 video_computation
|
| 45 |
+
167.7 1 video_sentence
|
| 46 |
+
170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
+
191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
sub-S20/func/sub-S20_task-localizer_events.tsv
ADDED
|
@@ -0,0 +1,81 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
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|
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|
|
|
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|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
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|
|
|
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|
|
|
|
|
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|
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|
|
|
|
|
|
|
|
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|
|
|
|
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
onset duration trial_type
|
| 2 |
+
0.0 1 video_computation
|
| 3 |
+
2.4 1 video_computation
|
| 4 |
+
8.7 1 horizontal_checkerboard
|
| 5 |
+
11.4 1 audio_right_hand
|
| 6 |
+
15.0 1 audio_sentence
|
| 7 |
+
18.0 1 video_right_hand
|
| 8 |
+
20.7 1 audio_sentence
|
| 9 |
+
23.7 1 audio_left_hand
|
| 10 |
+
26.7 1 video_left_hand
|
| 11 |
+
29.7 1 audio_sentence
|
| 12 |
+
33.0 1 vertical_checkerboard
|
| 13 |
+
35.4 1 audio_computation
|
| 14 |
+
39.0 1 video_sentence
|
| 15 |
+
41.7 1 video_sentence
|
| 16 |
+
44.7 1 audio_computation
|
| 17 |
+
48.0 1 audio_computation
|
| 18 |
+
56.4 1 video_sentence
|
| 19 |
+
59.7 1 horizontal_checkerboard
|
| 20 |
+
62.4 1 audio_left_hand
|
| 21 |
+
69.0 1 video_right_hand
|
| 22 |
+
71.4 1 video_left_hand
|
| 23 |
+
75.0 1 video_sentence
|
| 24 |
+
83.4 1 audio_computation
|
| 25 |
+
87.0 1 audio_right_hand
|
| 26 |
+
89.7 1 audio_sentence
|
| 27 |
+
96.0 1 vertical_checkerboard
|
| 28 |
+
108.0 1 audio_computation
|
| 29 |
+
116.7 1 video_left_hand
|
| 30 |
+
119.4 1 audio_sentence
|
| 31 |
+
122.7 1 vertical_checkerboard
|
| 32 |
+
125.4 1 video_computation
|
| 33 |
+
131.4 1 video_sentence
|
| 34 |
+
135.0 1 audio_computation
|
| 35 |
+
137.7 1 audio_computation
|
| 36 |
+
140.4 1 vertical_checkerboard
|
| 37 |
+
143.4 1 audio_right_hand
|
| 38 |
+
146.7 1 audio_sentence
|
| 39 |
+
149.4 1 horizontal_checkerboard
|
| 40 |
+
153.0 1 video_computation
|
| 41 |
+
156.0 1 vertical_checkerboard
|
| 42 |
+
159.0 1 video_sentence
|
| 43 |
+
162.0 1 audio_right_hand
|
| 44 |
+
164.4 1 video_computation
|
| 45 |
+
167.7 1 video_sentence
|
| 46 |
+
170.4 1 audio_left_hand
|
| 47 |
+
173.7 1 audio_computation
|
| 48 |
+
176.7 1 horizontal_checkerboard
|
| 49 |
+
188.4 1 horizontal_checkerboard
|
| 50 |
+
191.7 1 audio_computation
|
| 51 |
+
195.0 1 video_sentence
|
| 52 |
+
198.0 1 video_computation
|
| 53 |
+
201.0 1 video_computation
|
| 54 |
+
203.7 1 vertical_checkerboard
|
| 55 |
+
207.0 1 vertical_checkerboard
|
| 56 |
+
210.0 1 vertical_checkerboard
|
| 57 |
+
212.7 1 video_left_hand
|
| 58 |
+
215.7 1 video_left_hand
|
| 59 |
+
218.7 1 horizontal_checkerboard
|
| 60 |
+
221.4 1 video_computation
|
| 61 |
+
224.7 1 horizontal_checkerboard
|
| 62 |
+
227.7 1 video_right_hand
|
| 63 |
+
230.7 1 audio_right_hand
|
| 64 |
+
234.0 1 video_computation
|
| 65 |
+
236.7 1 audio_sentence
|
| 66 |
+
246.0 1 video_sentence
|
| 67 |
+
248.4 1 horizontal_checkerboard
|
| 68 |
+
251.7 1 audio_computation
|
| 69 |
+
254.7 1 audio_left_hand
|
| 70 |
+
257.4 1 audio_left_hand
|
| 71 |
+
260.4 1 video_computation
|
| 72 |
+
264.0 1 vertical_checkerboard
|
| 73 |
+
266.7 1 horizontal_checkerboard
|
| 74 |
+
269.7 1 horizontal_checkerboard
|
| 75 |
+
275.4 1 video_right_hand
|
| 76 |
+
278.4 1 vertical_checkerboard
|
| 77 |
+
284.4 1 audio_sentence
|
| 78 |
+
288.0 1 video_sentence
|
| 79 |
+
291.0 1 video_right_hand
|
| 80 |
+
293.4 1 audio_sentence
|
| 81 |
+
296.7 1 audio_sentence
|
task-localizer_bold.json
ADDED
|
@@ -0,0 +1,9 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
{
|
| 2 |
+
"TaskName": "Localizer",
|
| 3 |
+
"Manufacturer": "Brucker",
|
| 4 |
+
"MagneticFieldStrength": "3T",
|
| 5 |
+
"PulseSequenceType": "EPI",
|
| 6 |
+
"EchoTime": 0.03,
|
| 7 |
+
"RepetitionTime": 2.4,
|
| 8 |
+
"SliceThickness": "4"
|
| 9 |
+
}
|