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- license: apache-2.0
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- ---
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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+ ---
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+ license: apache-2.0
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+ ---
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+
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+ # Dataset Card for Synthetic Text-to-CT Scans - VLM3D Challenge
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+
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+ ## Dataset Details
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+
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+ ### Dataset Description
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+
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+ This dataset contains **1,000 synthetic 3D chest CT scans** generated using the model introduced in
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+ [*Text-to-CT Generation via 3D Latent Diffusion Model with Contrastive Vision-Language Pretraining*](https://arxiv.org/abs/2506.00633) (Molino et al., 2025).
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+
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+ The model was trained on the **CT-RATE dataset**, the largest publicly available collection of paired CT volumes and radiology reports.
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+ It leverages a **3D latent diffusion framework** combined with **contrastive vision-language pretraining (3D-CLIP)** to synthesize anatomically coherent and semantically faithful CT scans directly from clinical text prompts.
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+
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+ These 1,000 scans were generated for the **VLM3D Challenge - Task 4**, serving as a benchmark resource for multimodal evaluation and synthetic data research in medical imaging.
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+ - **Curated by:** ArCo Lab – Università Campus Bio-Medico di Roma & Umeå University
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+ - **Language(s):** Conditioning report are in English
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+ - **License:** Apache 2.0
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+
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+ ### Dataset Sources
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+
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+ - **Repository:** [GitHub Repository]()
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+ - **Paper:** [arXiv:2506.00633](https://arxiv.org/abs/2506.00633)
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+ - **Challenge:** [VLM3D Challenge](https://vlm3dchallenge.com)
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+
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+ ## Uses
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+
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+ ### Direct Use
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+ - Benchmarking text-to-CT generative models.
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+ - Data augmentation for classification, detection, or segmentation tasks.
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+ - Research in multimodal vision-language learning for 3D medical imaging.
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+ - Educational purposes and simulation in medical training.
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+
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+ ### Out-of-Scope Use
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+ - Direct diagnostic or clinical use.
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+ - Deployment in healthcare without proper validation and regulatory approval.
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+ - Any attempt to re-identify patients (note: scans are fully synthetic).
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+
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+ ## Dataset Structure
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+
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+ - **Format:** Volumetric CT scans stored in NIfTI (`.nii.gz`) format.
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+ - **Resolution:** Resampled to 0.75 × 0.75 × 3.0 mm voxel spacing, cropped/padded to 512 × 512 × 128.
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+ - **Intensity:** Normalized in Hounsfield Units (clipped to [−1000, +1000]).
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+ - **Content:** Synthetic chest CT scans across 18 pathological conditions (e.g., nodules, opacities, effusion, emphysema).
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+
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+ ## Dataset Creation
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+
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+ ### Curation Rationale
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+ Created to provide a reproducible benchmark for **text-to-CT generation** and to supply **synthetic volumetric data** for research in data augmentation, privacy preservation, and multimodal foundation models.
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+
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+ ### Source Data
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+ - Trained on **CT-RATE** (Hamamci et al., 2024), a large-scale dataset of chest CTs paired with radiology reports.
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+
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+ ### Annotations
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+ No manual annotations included; diagnostic semantics are embedded via the conditioning text prompts used during generation.
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+
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+ ### Personal and Sensitive Information
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+ - The dataset contains **no real patient data**.
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+ - All scans are **synthetic** and generated by a model trained on anonymized public datasets.
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+
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+ ## Bias, Risks, and Limitations
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+
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+ - Synthetic data may not fully capture rare pathologies or distributional nuances of real-world scans.
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+ - While useful for augmentation and benchmarking, these scans are **not clinically validated**.
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+ - There is a potential risk if synthetic data are used without acknowledging their limitations in medical research.
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+
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+ ### Recommendations
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+ Users should:
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+ - Combine synthetic with real-world data for downstream tasks.
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+ - Avoid over-relying on synthetic volumes for clinical translation.
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+ - Report the provenance of synthetic data when used in publications.
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+
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+ ## Citation
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+
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+ If you use this dataset, please cite the following work:
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+ **BibTeX:**
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+ ```bibtex
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+ @article{molino2025textct,
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+ title={Text-to-CT Generation via 3D Latent Diffusion Model with Contrastive Vision-Language Pretraining},
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+ author={Molino, Daniele and Caruso, Camillo Maria and Ruffini, Filippo and Soda, Paolo and Guarrasi, Valerio},
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+ journal={arXiv preprint arXiv:2506.00633},
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+ year={2025}
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+ }