sequence_length large_stringclasses 159 values | protein_name large_stringclasses 507 values | organism large_stringclasses 60 values | uniprotkb large_stringclasses 150 values | ec_number large_stringclasses 36 values | interpro large_stringclasses 126 values | pmid large_stringclasses 422 values | doi large_stringclasses 411 values | publication_year large_stringdate 1975-01-01 00:00:00 2023-01-01 00:00:00 ⌀ | source_dataset large_stringclasses 3 values | referencing_dataset large_stringclasses 65 values | wwpdb_raw large_stringclasses 138 values | ddg float64 -13.7 17.4 | domainome_ddg float64 | dg float64 -12 49.2 ⌀ | dh float64 -25.6 104 ⌀ | dhvh float64 -700 91 ⌀ | tm float64 28.3 112 ⌀ | dtm float64 -46.1 72 ⌀ | exp_temperature float64 -15 134 ⌀ | fitness float64 | ph float64 1.99 10.4 ⌀ | buffer_norm large_stringclasses 98 values | method_norm large_stringclasses 7 values | measure_norm large_stringclasses 21 values | stabilizing bool 2 classes | buffer_raw large_stringclasses 99 values | buffer_conc_raw large_stringclasses 70 values | ion_raw large_stringclasses 13 values | ion_conc_raw large_stringclasses 52 values | state large_stringclasses 3 values | pdb_id large_stringclasses 138 values | pdb_ids listlengths 0 4 | wt_residue large_stringclasses 20 values | position int64 1 12.8k | mut_residue large_stringclasses 20 values | mutation large_stringlengths 3 7 | sequence large_stringclasses 148 values | sequence_len_uniprot float64 53 34.4k ⌀ | sequence_length_num int64 32 34.4k | length_match bool 2 classes | protein_id large_stringlengths 6 14 | cluster_id large_stringlengths 6 24 | split large_stringclasses 1 value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2872918 | 10.1021/bi00358a035 | 1986 | ProTherm | null | 1WQ5 | -2.2 | null | 7.9 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | true | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | F | 22 | L | F22L | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2872918 | 10.1021/bi00358a035 | 1986 | ProTherm | null | 1WQ5 | 0.8 | null | 4.2 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | F | 22 | L | F22L | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | null | 1WQ5 | 2.3 | null | 2.3 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 28 | G | P28G | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | null | 1WQ5 | -0.7 | null | 4.9 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 28 | G | P28G | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 12215410 | 10.1016/s0022-2836(02)00737-4 | 2002 | ProTherm | null | 1WQ5 | 1.66 | null | 4.47 | null | null | null | null | 25 | null | 7.8 | potassium phosphate | Urea | CD | false | potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 28 | G | P28G | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 12215410 | 10.1016/s0022-2836(02)00737-4 | 2002 | ProTherm | null | 1WQ5 | -0.12 | null | 4.84 | null | null | null | null | 25 | null | 7.8 | potassium phosphate | Urea | CD | true | potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 28 | G | P28G | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | null | 1WQ5 | 1.6 | null | 7.2 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 10 mM | null | null | null | 1wq5 | [
"1wq5"
] | P | 28 | G | P28G | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | null | 1WQ5 | 2.4 | null | 2.2 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 28 | A | P28A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | null | 1WQ5 | 0.1 | null | 4.1 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 28 | A | P28A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 12215410 | 10.1016/s0022-2836(02)00737-4 | 2002 | ProTherm | null | 1WQ5 | 4.12 | null | 2.01 | null | null | null | null | 25 | null | 7.8 | potassium phosphate | Urea | CD | false | potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 28 | A | P28A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 12215410 | 10.1016/s0022-2836(02)00737-4 | 2002 | ProTherm | null | 1WQ5 | 0.91 | null | 3.81 | null | null | null | null | 25 | null | 7.8 | potassium phosphate | Urea | CD | false | potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 28 | A | P28A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 1.91 | null | 6.29 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | P | 28 | A | P28A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | null | 1WQ5 | 2.5 | null | 6.3 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 10 mM | null | null | null | 1wq5 | [
"1wq5"
] | P | 28 | A | P28A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 1.96 | null | 2.27 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 28 | A | P28A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | -0.05 | null | 4.04 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | true | Tris-HCl | 20 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 28 | A | P28A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 16023136 | 10.1016/j.jmb.2005.06.006 | 2005 | ProTherm | null | 1WQ5 | 1.41 | null | 4.72 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | I | 37 | A | I37A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 16023136 | 10.1016/j.jmb.2005.06.006 | 2005 | ProTherm | null | 1WQ5 | 3.01 | null | 1.71 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | I | 37 | A | I37A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | -0.08 | null | 18.24 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | G | E49G | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | -0.6 | null | 18.57 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | G | E49G | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 378988 | 10.1093/oxfordjournals.jbchem.a132423 | 1979 | ProTherm | null | 1WQ5 | 2.5 | null | 6.3 | null | null | null | null | 25.8 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 0.01 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | Q | E49Q | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | -3.6 | null | 8.5 | null | null | null | null | 25 | null | 9 | Tris-HCl | GdnHCl | CD | true | Tris-HCl | 0.025 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | Q | E49Q | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | 2.5 | null | 6.3 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 0.01 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | Q | E49Q | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | 2.4 | null | 2.8 | null | null | null | null | 25 | null | 5.5 | acetate | GdnHCl | CD | false | acetate | 0.05 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | Q | E49Q | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv, potapov_with_uniprot_mapping.csv | 1WQ5 | 0.23 | null | 17.93 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | Q | E49Q | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | -0.54 | null | 18.51 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | Q | E49Q | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | -3.1 | null | 8 | null | null | null | null | 25 | null | 9 | Tris-HCl | GdnHCl | CD | true | Tris-HCl | 0.025 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | S | E49S | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | 1.4 | null | 7.4 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 0.01 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | S | E49S | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | 1.3 | null | 3.9 | null | null | null | null | 25 | null | 5.5 | acetate | GdnHCl | CD | false | acetate | 0.05 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | S | E49S | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | 0.59 | null | 17.57 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | S | E49S | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | -0.09 | null | 18.06 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | S | E49S | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 378988 | 10.1093/oxfordjournals.jbchem.a132423 | 1979 | ProTherm | null | 1WQ5 | -4.6 | null | 13.4 | null | null | null | null | 25.8 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 0.01 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | M | E49M | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | -3.5 | null | 8.4 | null | null | null | null | 25 | null | 9 | Tris-HCl | GdnHCl | CD | true | Tris-HCl | 0.025 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | M | E49M | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | -4.5 | null | 13.3 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 0.01 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | M | E49M | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | -0.7 | null | 5.9 | null | null | null | null | 25 | null | 5.5 | acetate | GdnHCl | CD | true | acetate | 0.05 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | M | E49M | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2872918 | 10.1021/bi00358a035 | 1986 | ProTherm | null | 1WQ5 | -3.7 | null | 9.4 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | true | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | E | 49 | M | E49M | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2872918 | 10.1021/bi00358a035 | 1986 | ProTherm | null | 1WQ5 | -2 | null | 7 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | true | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | E | 49 | M | E49M | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | 0.05 | null | 18.11 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | M | E49M | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | -0.52 | null | 18.49 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | M | E49M | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | -4.5 | null | 9.4 | null | null | null | null | 25 | null | 9 | Tris-HCl | GdnHCl | CD | true | Tris-HCl | 0.025 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | V | E49V | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | -3.2 | null | 12 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 0.01 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | V | E49V | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | -0.9 | null | 6.1 | null | null | null | null | 25 | null | 5.5 | acetate | GdnHCl | CD | true | acetate | 0.05 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | V | E49V | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | -0.14 | null | 18.3 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | V | E49V | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | -1.01 | null | 18.98 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | V | E49V | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | -1.9 | null | 6.8 | null | null | null | null | 25 | null | 9 | Tris-HCl | GdnHCl | CD | true | Tris-HCl | 0.025 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | Y | E49Y | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 6757449 | 10.1016/0022-2836(82)90184-x | 1982 | ProTherm | null | 1WQ5 | 0.4 | null | 4.8 | null | null | null | null | 25 | null | 5.5 | acetate | GdnHCl | CD | false | acetate | 0.05 M | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | Y | E49Y | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | 0.17 | null | 17.99 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | Y | E49Y | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | -0.26 | null | 18.23 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | Y | E49Y | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | 0.08 | null | 18.08 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | A | E49A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | -0.59 | null | 18.56 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | A | E49A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | -0.46 | null | 18.62 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | I | E49I | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | -1.24 | null | 19.21 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | I | E49I | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | -0.44 | null | 18.6 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | L | E49L | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | -1.04 | null | 19.01 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | L | E49L | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | -0.8 | null | 18.77 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | P | E49P | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | 0.86 | null | 17.3 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | F | E49F | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | 0.02 | null | 17.95 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | F | E49F | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv, potapov_with_uniprot_mapping.csv, SAAFEC_S1262.csv | 1WQ5 | 0.97 | null | 17.19 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | W | E49W | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | potapov_with_uniprot_mapping.csv | 1WQ5 | 1.1 | null | 16.87 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | W | E49W | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | -0.33 | null | 18.49 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | H | E49H | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | -0.67 | null | 18.64 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | H | E49H | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv, potapov_with_uniprot_mapping.csv | 1WQ5 | -0.2 | null | 17.96 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | K | E49K | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | potapov_with_uniprot_mapping.csv | 1WQ5 | -0.39 | null | 18.36 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | K | E49K | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | 0.69 | null | 17.47 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | N | E49N | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv, potapov_with_uniprot_mapping.csv, SAAFEC_S1262.csv | 1WQ5 | -0.27 | null | 18.24 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | N | E49N | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | SAAFEC_S1262.csv | 1WQ5 | 0.8 | null | 17.36 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | D | E49D | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | 0.03 | null | 17.94 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | D | E49D | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv, potapov_with_uniprot_mapping.csv | 1WQ5 | -0.01 | null | 18.17 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | C | E49C | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | potapov_with_uniprot_mapping.csv | 1WQ5 | 0.13 | null | 17.84 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | C | E49C | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | null | 1WQ5 | 0.62 | null | 17.54 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | T | E49T | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 3299367 | 10.1073/pnas.84.13.4441 | 1987 | ProTherm | khan_protherm_data_mapped.csv | 1WQ5 | 0.26 | null | 17.71 | null | null | null | null | 25 | null | 9 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | E | 49 | T | E49T | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 16023136 | 10.1016/j.jmb.2005.06.006 | 2005 | ProTherm | null | 1WQ5 | 0.14 | null | 5.99 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | L | 50 | A | L50A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 16023136 | 10.1016/j.jmb.2005.06.006 | 2005 | ProTherm | null | 1WQ5 | 2.85 | null | 1.87 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | L | 50 | A | L50A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | null | 1WQ5 | 0.04 | null | null | null | null | null | null | 54.1 | null | 9 | Sodium tetraborate | Thermal | DSC | false | Sodium tetraborate | 1 mM | EDTA | 1 mM | null | 1wq5 | [
"1wq5"
] | P | 57 | A | P57A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 0.48 | null | 7.73 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | P | 57 | A | P57A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 0.24 | null | 4 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 57 | A | P57A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 0.24 | null | 3.76 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 57 | A | P57A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | null | 1WQ5 | 0.52 | null | null | null | null | null | null | 54.1 | null | 9 | Sodium tetraborate | Thermal | DSC | false | Sodium tetraborate | 1 mM | EDTA | 1 mM | null | 1wq5 | [
"1wq5"
] | P | 62 | A | P62A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 0.31 | null | 7.89 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | P | 62 | A | P62A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 0.69 | null | 3.54 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 62 | A | P62A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | -0.36 | null | 4.35 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | true | Tris-HCl | 20 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 62 | A | P62A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 8795042 | 10.1093/protein/9.5.425 | 1996 | ProTherm | khan_protherm_data_mapped.csv, potapov_with_uniprot_mapping.csv | 1WQ5 | 0.69 | null | 0.48 | null | null | null | null | 50 | null | 9 | Sodium tetraborate | Thermal | DSC | false | Sodium tetraborate | 1 mM | null | null | null | 1wq5 | [
"1wq5"
] | C | 81 | A | C81A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | khan_protherm_data_mapped.csv, potapov_with_uniprot_mapping.csv | 1WQ5 | 2 | null | null | null | null | null | null | 54.1 | null | 9 | Sodium tetraborate | Thermal | DSC | false | Sodium tetraborate | 1 mM | EDTA | 1 mM | null | 1wq5 | [
"1wq5"
] | P | 96 | A | P96A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 2.13 | null | 6.08 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | P | 96 | A | P96A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 1.6 | null | 2.63 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 96 | A | P96A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 0.55 | null | 3.44 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 96 | A | P96A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 16023136 | 10.1016/j.jmb.2005.06.006 | 2005 | ProTherm | null | 1WQ5 | 1.69 | null | 4.44 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | L | 99 | A | L99A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 16023136 | 10.1016/j.jmb.2005.06.006 | 2005 | ProTherm | null | 1WQ5 | 2.38 | null | 2.34 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | L | 99 | A | L99A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 16023136 | 10.1016/j.jmb.2005.06.006 | 2005 | ProTherm | SAAFEC_S1262.csv | 1WQ5 | 0.73 | null | 5.4 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | L | 127 | A | L127A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 16023136 | 10.1016/j.jmb.2005.06.006 | 2005 | ProTherm | SAAFEC_S1262.csv | 1WQ5 | 0.55 | null | 4.17 | null | null | null | null | 25 | null | 7.8 | Potassium phosphate | Urea | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | L | 127 | A | L127A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | khan_protherm_data_mapped.csv, potapov_with_uniprot_mapping.csv | 1WQ5 | 0.92 | null | null | null | null | null | null | 54.1 | null | 9 | Sodium tetraborate | Thermal | DSC | false | Sodium tetraborate | 1 mM | EDTA | 1 mM | null | 1wq5 | [
"1wq5"
] | P | 132 | A | P132A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 1.05 | null | 7.15 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | null | 1wq5 | [
"1wq5"
] | P | 132 | A | P132A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | 0.91 | null | 3.33 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | false | Tris-HCl | 20 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 132 | A | P132A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 9020793 | 10.1021/bi961660c | 1997 | ProTherm | null | 1WQ5 | -0.14 | null | 3.85 | null | null | null | null | 25 | null | 7 | Tris-HCl | GdnHCl | CD | true | Tris-HCl | 20 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 132 | A | P132A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | khan_protherm_data_mapped.csv, potapov_with_uniprot_mapping.csv | 1WQ5 | 0.78 | null | null | null | null | null | null | 54.1 | null | 9 | Sodium tetraborate | Thermal | DSC | false | Sodium tetraborate | 1 mM | EDTA | 1 mM | null | 1wq5 | [
"1wq5"
] | P | 132 | G | P132G | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | null | 1WQ5 | 1 | null | 3.6 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 132 | G | P132G | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | SAAFEC_S1262.csv | 1WQ5 | -0.4 | null | 4.6 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | true | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | P | 132 | G | P132G | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 2008436 | 10.1002/prot.340090203 | 1991 | ProTherm | null | 1WQ5 | 0.6 | null | 8.2 | null | null | null | null | 25 | null | 7 | Potassium phosphate | GdnHCl | CD | false | Potassium phosphate | 10 mM | null | null | null | 1wq5 | [
"1wq5"
] | P | 132 | G | P132G | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 7629069 | 10.1074/jbc.270.30.17712 | 1995 | ProTherm | SAAFEC_S1262.csv | 1WQ5 | 0.7 | null | 5.7 | null | null | null | null | 23 | null | 7.8 | Potassium phosphate | Urea | Absorbance | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | F | 139 | W | F139W | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 7629069 | 10.1074/jbc.270.30.17712 | 1995 | ProTherm | SAAFEC_S1262.csv | 1WQ5 | 0.6 | null | 4.6 | null | null | null | null | 23 | null | 7.8 | Potassium phosphate | Urea | Absorbance | false | Potassium phosphate | 10 mM | null | null | 3.0 | 1wq5 | [
"1wq5"
] | F | 139 | W | F139W | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
268 | Tryptophan synthase alpha chain | Escherichia coli (strain K12) | P0A877 | 4.2.1.20 | IPR013785:Aldolase_TIM, IPR011060:RibuloseP-bd_barrel, IPR018204:Trp_synthase_alpha_AS, IPR002028:Trp_synthase_suA | 8795042 | 10.1093/protein/9.5.425 | 1996 | ProTherm | khan_protherm_data_mapped.csv, potapov_with_uniprot_mapping.csv | 1WQ5 | 1.03 | null | 0.14 | null | null | null | null | 50 | null | 9 | Sodium tetraborate | Thermal | DSC | false | Sodium tetraborate | 1 mM | null | null | null | 1wq5 | [
"1wq5"
] | C | 154 | A | C154A | MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS | 268 | 268 | true | P0A877 | P00929 | train |
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