diff --git "a/test.jsonl" "b/test.jsonl" new file mode 100644--- /dev/null +++ "b/test.jsonl" @@ -0,0 +1,13346 @@ +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-V-T-K-E-Q-K-A-S-I-V-K-K-F-G-A-S-E-K-D-T-G-D-V-K-V-Q-I-A-L-L-T-E-K-I-N-Q-L-T-N-H-C-K-D-H-P-K-D-A-G-S-R-R-G-L-I-S-M-V-G-H-R-R-S-L-L-K-Y-Y-R-R-T-D-I-E-G-Y-R-T-I-L-K-E-L-N-L-R-K"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-D-D-L-F-K-K-I-Q-Q-L-I-A-A-K-L-E-I-D-E-D-K-V-T-L-D-S-S-F-R-Q-D-L-G-A-D-S-L-D-T-Y-E-L-V-Y-A-L-E-E-D-M-G-I-K-I-P-D-E-K-A-N-E-F-E-T-V-R-D-A-Y-E-F-I-K-S-Q-Q-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-R-G-G-D-I-A-K-G-T-V-L-L-N-K-G-T-P-Y-L-V-V-E-R-E-F-V-N-P-G-K-G-A-A-F-A-R-V-K-M-K-N-L-R-D-G-S-V-L-M-Q-T-I-K-T-A-D-T-V-E-D-A-V-V-D-T-H-K-C-Q-Y-Q-Y-K-D-G-D-Q-F-M-F-M-D-T-E-S-F-E-S-I-S-V-P-A-E-T-I-G-D-K-E-H-Y-L-R-E-G-D-E-Y-D-I-L-I-W-E-N-E-P-I-D-V-R-I-P-T-K-M-I-F-I-V-E-Q-S-E-N-Y-I-K-G-D-T-V-S-G-A-T-K-P-I-V-T-E-T-G-L-V-V-R-V-P-L-F-I-K-Q-G-E-K-I-L-V-N-T-E-T-N-E-Y-Q-E-R-V-N-S"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-V-K-P-L-G-D-R-V-L-V-K-P-D-A-V-E-T-K-T-A-G-G-I-I-I-P-D-T-A-Q-E-K-T-Q-R-G-V-V-V-A-V-G-D-D-K-E-K-I-K-V-S-V-G-Q-K-V-I-H-D-K-Y-A-G-T-Q-I-Q-I-D-G-V-D-H-L-I-L-K-S-N-D-L-V-A-V-V-E"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-D-L-I-M-K-I-E-A-Q-Q-K-A-E-N-P-P-V-F-R-V-G-D-T-V-K-V-H-F-K-I-V-E-G-K-T-E-R-I-Q-V-Y-E-G-L-V-I-C-F-K-N-S-G-I-G-R-T-F-T-V-R-K-N-S-Y-G-V-G-V-E-R-V-F-P-L-H-S-P-R-I-A-K-V-E-V-V-R-P-G-K-V-R-R-A-K-L-Y-Y-I-R-D-K-V-G-K-A-A-K-I-K-T-L-I-T-K-K-N-S"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-D-L-L-A-T-G-R-I-R-G-T-F-G-I-E-G-F-V-K-V-E-S-F-S-G-E-Y-E-H-F-L-G-F-D-R-V-F-L-S-I-L-K-E-K-L-R-E-Q-K-Y-K-D-G-W-F-E-I-E-E-V-N-L-R-K-A-D-A-L-V-K-F-K-G-I-D-N-P-E-A-A-K-C-L-T-G-S-E-L-F-I-P-R-D-K-A-A-P-L-D-E-G-E-V-Y-V-H-D-L-C-N-C-N-L-V-C-E-G-T-L-V-G-K-I-T-S-V-A-E-G-G-G-G-Y-L-L-E-I-A-G-K-T-S-E-A-A-A-E-S-S-F-Y-V-P-F-N-K-E-F-I-G-K-I-D-L-K-A-K-T-V-E-L-M-H-R-W-I-L-E"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-I-F-F-K-E-H-E-A-P-R-S-W-Y-L-I-D-A-A-G-K-P-L-G-R-V-A-A-K-T-A-A-M-L-R-G-K-H-K-V-S-F-A-P-H-Q-E-I-G-D-Y-V-V-I-I-N-A-E-K-V-A-V-T-G-N-K-A-K-D-K-M-Y-Y-T-H-S-G-Y-V-G-G-L-K-S-I-N-F-N-G-L-I-A-K-K-P-A-E-P-L-M-I-A-I-K-G-M-L-P-K-G-P-L-G-R-K-L-L-T-N-V-K-V-Y-A-G-P-E-H-P-H-Q-A-Q-N-P-I-A-V-E-V"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-T-V-K-K-R-K-E-K-K-S-I-Y-E-G-N-V-Y-I-Q-A-T-F-N-N-T-I-I-T-I-T-D-L-K-G-N-V-L-S-W-A-S-S-G-G-L-G-F-A-G-A-K-K-S-T-P-F-A-A-Q-T-V-A-E-T-A-V-Q-K-C-Q-P-Y-G-L-H-E-V-H-V-F-V-K-G-P-G-V-G-R-E-S-A-I-R-T-L-G-T-M-G-L-K-V-R-S-I-S-D-V-T-P-I-P-H-N-G-C-R-P-K-K-T-R-R-I"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-L-P-N-K-H-V-N-V-S-L-T-Y-I-Y-G-I-S-T-S-S-A-N-K-I-C-E-A-T-K-V-D-P-M-K-K-M-N-D-L-D-E-A-E-L-A-A-I-R-E-V-I-D-R-E-Y-K-V-E-G-R-L-R-T-E-V-A-L-N-I-K-R-L-Q-D-I-G-C-Y-R-G-Q-R-H-R-K-G-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-K-K-K-T-V-A-G-K-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-F-E-F-N-L-T-V-P-A-G-A-T-H-K-K-K-I-V-G-R-G-S-S-S-G-W-G-K-T-S-G-K-G-H-K-G-Q-Q-A-R-S-G-G-K-V-Y-A-G-F-E-G-G-Q-M-P-L-Y-R-R-V-A-K-K-G-F-S-N-Y-P-F-K-K-E-F-Y-V-V-N-L-A-M-L-E-T-K-Y-S-D-G-E-T-V-N-K-E-S-L-M-Q-K-G-L-L-R-K-G-S-L-Y-V-K-V-L-G-T-G-D-I-T-K-K-L-T-V-D-V-D-R-I-S-A-S-A-K-E-K-I-E-K-A-G-G-T-I-V-Q-S-E-A"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-H-Q-K-E-S-K-R-D-N-Q-H-T-D-K-E-Y-V-E-K-L-V-K-L-N-R-T-A-K-V-V-K-G-G-R-R-F-S-F-S-A-L-T-V-V-G-D-Q-K-G-R-V-G-Y-G-F-G-K-A-N-D-V-S-D-A-I-R-K-S-I-E-K-A-K-A-N-M-V-T-F-P-L-K-N-G-T-I-P-H-E-V-Q-G-K-F-K-G-S-S-V-L-L-R-P-A-C-S-G-T-G-I-I-A-G-G-T-I-R-A-I-M-E-A-A-G-A-T-D-L-L-S-K-S-L-G-S-S-S-A-V-N-V-V-K-A-T-F-D-A-A-S-L-L-M-D-G-K-K-I-A-K-S-R-G-K-T-L-L-D-V-W-G"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-R-N-D-K-D-R-K-R-F-K-R-K-M-H-I-R-K-S-I-F-G-T-A-E-R-P-R-M-T-V-F-R-S-N-K-R-I-S-V-Q-V-I-D-D-V-E-G-K-T-L-A-A-V-S-T-M-E-E-A-L-R-S-L-K-V-N-V-E-S-G-A-K-V-G-E-E-I-G-K-R-L-K-E-K-N-I-D-T-V-V-F-D-R-N-G-Y-L-Y-H-G-V-V-K-A-V-A-D-G-A-R-K-T-G-I-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-M-P-V-A-I-P-A-G-V-K-V-N-V-A-N-G-I-F-T-V-E-G-P-K-G-K-L-S-Q-D-Y-H-T-E-A-V-D-F-K-I-E-G-D-H-V-L-V-T-R-K-D-D-E-L-Q-T-R-A-Y-H-G-L-Y-R-S-L-L-N-N-M-V-T-G-V-S-T-G-F-T-K-T-L-V-I-N-G-V-G-Y-R-A-E-V-Q-G-K-L-L-V-M-A-L-G-Y-S-N-D-F-S-V-I-I-P-E-G-I-E-V-K-V-D-Q-L-K-V-I-I-S-G-A-S-K-E-A-V-G-Q-F-A-S-Q-V-R-K-L-R-G-P-E-P-Y-K-G-K-G-I-R-Y-E-D-E-I-I-K-R-K-V-G-K-S-G-V-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-V-S-D-P-I-A-D-M-L-T-K-I-R-N-A-A-S-A-G-H-E-S-V-D-V-P-S-S-K-M-K-W-E-I-I-S-I-L-K-S-E-G-Y-I-K-N-F-K-K-M-T-Q-E-G-A-G-N-I-R-V-F-L-K-Y-D-D-K-E-S-S-V-I-H-G-I-E-R-V-S-T-P-G-R-R-V-Y-L-G-Y-K-S-L-P-R-V-F-N-G-Y-G-T-L-I-V-S-T-S-K-G-I-I-T-G-K-A-A-G-E-S-Q-V-G-G-E-L-I-C-K-V-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-T-V-A-K-I-N-Q-A-N-R-K-A-K-Y-P-T-R-Q-Y-N-R-C-K-V-C-G-R-P-R-G-Y-L-R-K-F-K-M-C-R-V-C-F-R-K-L-A-S-E-G-Q-I-P-G-V-T-K-S-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-N-Y-V-P-R-L-K-K-V-Y-T-E-Q-I-M-P-E-L-K-K-E-F-N-Y-S-S-V-M-Q-I-P-R-L-K-K-V-V-V-S-M-G-V-G-V-A-L-T-N-R-K-L-L-D-A-A-V-T-D-L-E-T-I-T-G-Q-K-A-V-K-T-K-A-R-K-S-I-A-N-F-K-L-R-E-G-N-E-I-G-A-M-V-T-L-R-G-A-R-M-Y-E-F-L-D-R-F-I-N-V-A-L-P-R-V-K-D-F-R-G-V-N-P-N-G-F-D-G-R-G-N-Y-S-V-G-I-T-E-Q-I-I-F-P-E-I-D-F-D-K-I-E-R-I-S-G-L-N-V-N-V-V-T-S-A-E-T-D-Q-E-A-R-S-L-L-A-K-F-G-M-P-F-R-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-G-K-M-K-I-R-R-N-D-S-V-E-I-I-A-G-K-E-R-G-K-R-G-E-V-V-K-V-L-Q-E-D-N-K-V-I-V-G-G-L-N-M-I-K-K-A-M-R-K-R-S-Q-Q-D-Q-G-G-I-V-E-I-E-A-P-I-S-A-S-N-V-M-V-I-C-K-K-C-G-K-T-R-I-A-Y-E-I-K-D-G-K-K-T-R-I-C-R-K-C-G-E-A-L"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-V-E-T-R-L-N-V-A-D-N-S-G-A-K-L-V-E-C-I-K-V-I-G-G-S-K-R-R-Y-A-G-I-G-D-I-I-V-V-A-V-K-E-A-L-P-T-S-V-I-K-K-G-T-V-E-K-A-V-I-V-R-V-S-K-E-Y-R-R-P-D-G-T-Y-I-R-F-D-D-N-A-C-V-I-V-D-D-N-K-N-P-K-G-K-R-I-F-G-P-V-A-R-E-L-R-D-H-D-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-T-T-E-N-T-K-K-I-G-K-R-E-F-V-G-I-V-T-S-D-K-M-N-K-T-I-V-V-E-V-R-T-K-K-L-H-K-L-Y-K-K-Y-V-S-S-S-K-K-Y-K-A-H-D-E-E-N-T-A-H-I-G-D-T-V-R-I-V-E-H-K-P-I-S-K-D-K-A-W-M-L-T-E-V-I-E-R-A-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-A-F-S-P-K-R-V-K-H-R-K-V-Q-R-G-R-I-K-G-E-A-T-R-C-N-N-I-D-F-G-D-Y-A-L-V-S-L-E-P-F-L-L-T-N-R-Q-I-E-A-A-R-V-A-L-N-R-K-I-K-R-G-G-K-L-W-I-R-V-F-P-D-K-P-Y-S-K-K-P-A-E-V-R-M-G-G-G-K-G-A-P-E-Y-W-V-A-V-V-K-P-G-T-I-I-F-E-L-A-G-V-D-K-N-L-A-E-Q-A-M-T-L-A-G-S-K-L-P-F-K-T-R-F-A-E-Q-I-Q-A-D"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-T-E-R-T-G-Y-R-A-T-T-K-F-L-I-A-S-P-T-K-V-R-P-V-A-N-V-V-K-N-K-P-Y-P-E-A-M-A-I-L-E-N-M-P-Q-K-G-A-V-L-I-S-Q-T-M-K-S-A-A-S-N-A-L-Y-K-N-K-Q-L-D-E-D-M-L-F-V-K-E-I-M-I-D-E-G-P-R-L-K-R-I-W-C-R-G-K-G-R-A-D-I-L-L-K-R-M-C-H-I-T-V-V-V-D-E-R-A-G-E"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-V-K-K-G-P-F-I-A-K-S-L-F-K-N-V-N-E-M-N-R-S-G-K-K-K-P-I-K-T-Y-S-R-C-S-T-I-I-P-E-M-V-G-N-T-I-S-V-H-N-G-K-T-W-I-P-V-Y-I-T-E-N-L-V-G-H-K-L-G-E-F-A-P-T-R-T-F-R-K-H-A-N-S-D-K-K-V-G-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-E-Y-N-D-I-L-I-A-P-V-L-T-E-K-S-T-E-L-R-E-Q-G-K-Y-V-F-K-V-A-P-K-A-T-K-I-Q-I-K-E-A-V-R-R-L-F-N-V-K-V-T-D-C-T-V-V-N-V-R-G-K-T-K-R-L-R-Y-K-E-G-K-T-S-S-W-K-K-A-T-V-K-L-A-K-G-E-T-I-K-I-F-E-G-A"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-T-K-E-K-I-R-V-K-L-R-G-F-D-V-E-L-V-D-Q-S-S-K-A-I-V-Q-A-V-Q-K-A-G-A-K-V-C-G-P-I-P-L-P-T-R-I-N-K-F-T-V-L-R-S-P-H-V-N-K-K-S-R-E-Q-F-E-M-R-T-H-K-R-L-I-D-I-I-E-P-S-A-E-V-M-N-A-L-L-A-L-E-L-S-A-G-V-D-V-E-I-K-Q"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-R-V-I-V-F-F-D-L-P-V-I-T-P-E-N-R-H-N-Y-S-V-F-R-K-Y-L-I-K-S-G-F-I-M-Q-Q-K-S-V-Y-S-K-L-V-L-N-L-T-N-R-D-S-I-V-K-S-I-E-K-N-K-P-P-E-G-L-V-E-V-L-T-V-T-E-K-Q-Y-A-K-M-E-I-I-I-G-E-S-K-T-E-Y-L-N-T-D-E-R-L-V-V-L"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-P-T-Y-A-P-K-A-G-D-T-T-R-S-W-Y-V-I-D-A-T-D-V-V-L-G-R-L-A-V-A-A-A-N-L-L-R-G-K-H-K-P-T-F-A-P-N-V-D-G-G-D-F-V-I-V-V-N-A-D-K-V-A-F-S-G-Q-K-L-D-K-K-L-A-Y-R-H-S-G-Y-P-G-G-L-R-S-R-T-I-G-E-L-M-Q-K-H-P-D-R-V-V-A-D-A-I-V-G-M-L-P-K-N-K-L-S-R-Q-I-Q-R-K-L-R-V-Y-A-G-P-E-H-P-H-T-A-Q-Q-P-I-P-Y-E-I-K-Q-V-A-Q"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-P-P-A-K-K-A-A-A-A-P-K-K-G-Q-K-T-R-R-R-E-K-K-N-V-P-H-G-A-A-H-I-K-S-T-F-N-N-T-I-V-T-I-T-D-P-Q-G-N-V-I-A-W-A-S-S-G-H-V-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-L-A-A-E-N-A-A-R-K-A-Q-E-H-G-V-R-K-V-D-V-F-V-K-G-P-G-S-G-R-E-T-A-I-R-S-L-Q-A-A-G-L-E-V-G-A-I-S-D-V-T-P-Q-P-H-N-G-V-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-L-V-G-V-D-L-P-R-D-K-R-M-E-I-A-L-T-Y-I-Y-G-V-G-R-T-R-S-N-E-I-L-A-A-T-G-I-D-R-D-L-R-T-R-D-L-T-D-D-Q-L-T-H-L-R-D-Y-I-E-A-N-L-K-V-E-G-D-L-R-R-E-V-Q-A-D-I-R-R-K-I-E-I-G-C-Y-Q-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-K-R-T-I-A-G-K-K-K-A-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-I-K-L-H-D-L-K-P-A-R-G-S-K-T-P-R-T-R-V-G-R-G-E-G-S-K-G-K-T-A-G-R-G-T-K-G-T-K-A-R-K-N-V-P-V-T-F-E-G-G-Q-M-P-I-H-M-R-L-P-K-L-K-G-F-R-N-R-F-R-T-E-Y-E-I-V-N-V-G-D-I-N-R-L-F-P-Q-G-G-S-V-G-V-D-E-L-V-A-K-G-A-V-R-R-N-S-L-V-K-V-L-G-D-G-K-L-T-V-K-V-E-V-S-A-H-K-F-S-G-S-A-R-E-K-I-T-A-A-G-G-S-V-T-E-L"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-Q-T-Q-A-D-T-A-A-R-K-P-V-G-Q-S-V-S-A-T-R-R-V-S-R-L-R-R-H-A-R-L-R-K-K-I-A-G-T-P-E-R-P-R-L-V-V-N-R-S-A-R-H-I-H-V-Q-L-V-N-D-E-N-G-T-T-V-A-A-A-S-S-I-E-D-D-V-R-S-L-Q-G-D-K-K-A-R-S-V-R-V-G-Q-L-I-A-E-R-A-K-A-A-G-I-D-S-V-V-F-D-R-G-G-Y-T-Y-G-G-R-I-A-A-L-A-D-A-A-R-E-N-G-L-Q-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-Q-P-V-P-V-P-A-G-V-D-V-T-I-D-G-Q-K-V-S-V-K-G-P-K-G-T-L-D-L-T-V-A-E-P-I-T-V-S-R-N-D-D-G-A-I-V-V-T-R-P-N-D-E-R-R-N-R-S-L-H-G-L-S-R-T-L-V-S-N-L-V-T-G-V-T-Q-G-Y-T-T-K-M-E-I-F-G-V-G-Y-R-V-Q-L-K-G-S-N-L-E-F-A-L-G-Y-S-H-P-V-V-I-E-A-P-E-G-I-T-F-A-V-Q-S-P-T-K-F-S-I-S-G-I-D-K-Q-K-V-G-Q-I-S-A-N-I-R-R-L-R-R-P-D-P-Y-K-G-K-G-V-R-Y-E-G-E-Q-I-R-R-K-V-G-K-T-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-I-A-D-F-L-T-R-L-R-N-A-N-S-A-Y-H-D-E-V-T-L-P-H-S-K-L-K-A-N-I-A-Q-I-L-K-N-E-G-Y-I-S-D-F-R-T-E-D-A-R-V-G-K-S-L-I-V-Q-L-K-Y-G-P-S-R-E-R-S-I-A-G-L-R-R-V-S-K-P-G-L-R-V-Y-A-K-S-T-N-L-P-R-V-L-G-G-L-G-V-A-I-I-S-T-S-S-G-L-L-T-D-R-Q-A-A-R-Q-G-V-G-G-E-V-L-A-Y-V-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-A-L-V-N-K-A-A-R-K-P-K-F-A-V-R-G-Y-T-R-C-N-K-C-G-R-P-R-A-V-F-R-K-F-G-L-C-R-I-C-L-R-E-M-A-H-A-G-E-L-P-G-V-Q-K-S-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-T-T-E-K-V-Q-P-R-L-K-E-R-Y-R-N-E-I-R-D-S-L-Q-Q-Q-F-G-S-A-N-V-M-Q-I-P-T-V-T-K-V-V-V-N-M-G-I-G-E-A-A-R-D-A-K-L-I-N-G-A-V-N-D-L-A-L-I-T-G-Q-R-P-E-I-R-R-A-R-K-S-I-A-Q-F-K-L-R-E-G-M-P-I-G-A-R-V-T-L-R-G-D-R-M-W-E-F-L-D-R-L-T-S-I-A-L-P-R-I-R-D-F-R-G-L-S-S-K-Q-F-D-G-V-G-N-Y-T-F-G-L-A-E-Q-S-V-F-H-E-I-D-V-D-K-I-D-R-V-R-G-M-D-I-N-V-V-T-S-A-T-T-D-D-E-G-R-A-L-L-R-A-L-G-F-P-F-K-E-N"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-T-G-A-K-E-I-L-C-I-R-V-L-G-G-S-S-R-R-Y-A-G-I-G-D-V-I-V-A-T-V-K-D-A-I-P-G-G-N-V-K-R-G-D-V-V-K-A-V-V-V-R-T-V-K-E-R-R-R-P-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-K-P-D-N-D-P-R-G-T-R-I-F-G-P-V-G-R-E-L-R-E-K-R-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-M-A-E-A-K-K-A-A-P-K-K-A-A-T-A-A-S-K-D-A-D-A-K-G-P-K-H-T-P-P-N-P-K-V-R-G-R-R-K-T-R-I-G-Y-V-V-S-D-K-M-Q-K-T-I-V-V-E-L-E-D-R-V-K-H-P-L-Y-G-K-I-I-R-T-T-K-K-V-K-A-H-D-E-N-S-I-A-G-I-G-D-R-V-S-L-M-E-T-R-P-T-S-A-T-K-R-W-R-L-V-E-I-L-E-K-A-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-I-P-R-K-V-K-H-R-K-Q-H-H-P-R-Q-R-G-I-A-S-G-G-T-A-V-N-F-G-D-Y-G-I-Q-A-L-E-H-A-Y-V-T-N-R-Q-I-E-S-A-R-I-A-I-N-R-H-I-K-R-G-G-K-V-W-I-N-V-F-P-D-R-P-L-T-K-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-W-W-V-V-N-V-K-P-G-R-V-L-F-E-L-S-Y-P-N-E-Q-T-A-R-A-A-L-T-R-A-I-H-K-L-P-I-K-A-R-I-V-T-R-E-D-Q-F"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-T-T-T-E-F-P-S-A-V-A-K-A-R-F-V-R-V-S-P-R-K-A-R-R-V-I-D-L-V-R-G-R-S-V-T-D-A-L-D-I-L-R-W-A-P-Q-A-A-S-E-P-V-A-K-V-I-A-S-A-A-A-N-A-Q-N-N-N-G-L-D-P-A-T-L-V-V-A-T-V-Y-A-D-E-G-P-T-A-K-R-I-R-P-R-A-Q-G-R-A-F-R-I-R-K-R-T-S-H-I-T-V-V-V-E-S-R-P-A-K-D-Q-R-S-A-K-S-S-R-T-R-R-A-E-A-S-K-A-A-A-K-A-P-A-K-K-A-P-A-K-K-A-P-A-K-K-A-P-A-K-T-A-A-K-K-A-P-A-K-T-S-E-T-S-D-A-K-G-G-S-D"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-V-D-G-H-L-L-K-K-V-D-A-Q-N-E-K-N-T-K-Q-V-I-K-T-W-S-R-R-S-T-I-I-P-D-F-I-G-H-T-F-A-V-H-D-G-R-K-H-V-P-V-F-V-T-E-A-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-K-G-H-I-K-D-D-R-K-A-K-R-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-A-T-V-T-D-P-R-D-I-I-L-A-P-V-I-S-E-K-S-Y-S-L-L-D-D-N-V-Y-T-F-V-V-H-P-D-S-N-K-T-Q-I-K-I-A-I-E-K-I-F-S-V-K-V-A-S-V-N-T-A-N-R-Q-G-K-R-K-R-T-R-T-G-F-G-K-R-K-S-T-K-R-A-I-V-T-L-A-P-G-S-K-P-I-D-L-F-G-A-P-A"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-G-Q-K-I-R-I-R-L-K-A-Y-D-H-E-A-I-D-A-S-A-R-K-I-V-E-T-V-V-R-T-G-A-S-V-V-G-P-V-P-L-P-T-E-K-N-V-Y-C-V-I-R-S-P-H-K-Y-K-D-S-R-E-H-F-E-M-R-T-H-K-R-L-I-D-I-L-D-P-T-P-K-T-V-D-A-L-M-R-I-D-L-P-A-S-V-D-V-N-I-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-A-P-K-R-P-L-V-N-D-P-V-Y-G-S-Q-L-V-T-Q-L-V-N-K-V-L-L-K-G-K-K-S-L-A-E-R-I-V-Y-G-A-L-E-N-A-R-E-K-T-G-T-D-P-V-I-T-L-K-R-A-L-D-N-V-K-P-A-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-P-D-R-S-T-T-L-A-L-R-W-L-V-S-F-S-R-Q-R-R-E-K-T-M-V-E-R-L-A-N-E-I-L-D-A-S-N-G-L-G-A-S-V-K-R-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-Q-Q-L-V-R-K-G-R-R-D-K-I-G-K-V-K-T-A-A-L-K-G-S-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-K-L-T-S-Q-V-E-V-T-A-Y-I-P-G-E-G-H-N-L-Q-E-H-S-M-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-K-I-I-R-G-S-L-D-T-Q-G-V-K-N-R-K-Q-A-R-S-R-Y-G-A-K-K-E-K-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-M-S-T-D-D-L-L-D-A-F-K-E-M-T-L-L-E-L-S-D-F-V-K-K-F-E-E-T-F-E-V-T-A-A-A-P-V-A-V-A-A-A-G-P-A-A-G-G-A-P-A-E-A-A-E-E-Q-S-E-F-D-V-I-L-E-S-A-G-D-K-K-I-G-V-I-K-V-V-R-E-I-V-S-G-L-G-L-K-E-A-K-D-L-V-D-G-A-P-K-P-L-L-E-K-V-A-K-E-A-A-D-D-A-K-A-K-L-E-A-A-G-A-T-V-T-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-R-A-D-K-A-T-A-V-A-D-I-A-E-Q-F-K-E-A-T-A-T-L-I-T-E-Y-R-G-L-T-V-A-N-L-A-E-L-R-R-S-L-S-G-A-A-T-Y-S-V-A-K-N-T-L-V-K-R-A-A-S-E-A-G-I-E-G-L-D-E-L-F-A-G-P-T-A-I-A-F-V-T-G-E-P-V-D-A-A-K-A-I-K-T-F-A-K-E-H-K-A-L-V-I-K-G-G-Y-M-D-G-R-A-L-S-V-A-E-V-E-R-I-A-D-L-E-S-R-E-V-L-L-A-K-L-A-G-A-M-K-G-N-L-A-K-A-A-G-L-F-N-A-P-A-S-Q-V-A-R-L-A-A-A-L-Q-E-K-K-A-A-E-G-P-A-E-A-P-Q-P-A-T-E-P-P-A-E-A-P-E-A-P-A-D-A-E"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-V-V-P-I-R-I-V-G-D-P-V-L-H-T-P-T-Q-P-V-P-V-G-D-D-G-S-L-P-A-D-L-G-K-L-I-A-D-M-Y-D-T-M-D-A-A-H-G-V-G-L-A-A-N-Q-I-G-V-G-L-R-V-F-V-Y-D-C-A-D-D-R-G-L-T-E-R-R-R-G-V-V-V-N-P-V-L-E-T-S-E-I-P-E-T-M-P-D-P-D-T-D-D-E-G-C-L-S-V-P-G-E-S-F-P-T-G-R-A-S-W-A-R-V-T-G-L-D-A-D-G-N-P-V-S-I-E-G-H-G-L-F-A-R-M-L-Q-H-E-T-G-H-L-D-G-F-L-Y-L-D-R-L-I-G-R-Y-A-R-S-A-K-R-A-V-K-S-H-N-W-G-V-P-G-L-S-W-M-P-G-E-G-P-D-P-F-G-H"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-V-K-N-D-R-R-R-A-T-V-A-R-Y-A-E-R-R-A-E-L-K-E-I-I-R-S-P-R-S-T-P-E-Q-R-T-A-A-Q-N-E-L-A-H-Q-P-R-D-A-S-A-V-R-V-R-N-R-D-A-V-D-G-R-P-R-G-H-L-R-K-F-G-L-S-R-V-R-V-R-E-L-A-H-A-G-Q-L-P-G-V-R-K-A-S-W"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-P-K-K-P-A-R-T-R-R-P-A-P-L-A-G-R-A-R-K-K-N-L-L-D-S-L-G-L-R-T-V-D-Y-K-D-T-A-T-L-R-V-F-I-S-E-R-G-K-I-R-S-R-Q-V-T-G-L-S-V-Q-Q-Q-R-Q-V-A-T-A-I-K-N-A-R-E-M-A-L-L-P-Y-P-G-Q-G-I-K-P"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-T-N-T-Q-K-A-I-L-A-G-G-C-F-W-G-M-Q-E-L-I-R-K-Q-P-G-V-V-S-T-R-V-G-Y-T-G-G-D-V-P-N-A-T-Y-R-N-H-G-T-H-A-E-A-V-E-I-I-Y-D-P-A-V-T-D-Y-R-Q-I-L-E-F-F-F-Q-I-H-D-P-T-T-K-D-R-Q-G-N-D-R-G-P-S-Y-R-S-A-I-F-Y-T-D-D-E-Q-K-R-I-A-L-D-T-I-A-D-V-E-A-S-G-L-W-P-G-K-V-V-T-E-V-S-P-A-G-D-F-W-E-A-E-P-E-H-Q-D-Y-L-Q-R-Y-P-N-G-Y-T-C-H-Y-I-R-P-G-W-K-L-P-R-R-A-T-S-G-S"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-G-S-G-R-A-K-A-A-G-G-K-G-G-S-K-Q-I-I-A-T-N-R-K-A-R-H-N-Y-S-I-I-E-T-Y-E-A-G-V-A-L-Q-G-T-E-V-K-S-L-R-E-G-Q-A-S-L-A-D-A-F-A-T-I-D-D-G-E-V-W-L-R-N-L-Y-I-P-E-Y-Q-H-G-S-W-T-N-H-D-P-R-R-N-R-K-L-L-L-H-R-Q-Q-I-D-R-L-V-G-K-I-R-D-G-N-L-A-L-M-P-L-S-L-Y-F-S-E-G-K-V-K-V-E-L-A-L-A-R-G-K-K-A-Y-D-K-R-Q-D-L-A-Q-R-D-A-Q-R-E-V-V-R-Q-L-G-R-R-T-K-G-M-I"} +{"text": "### FUNCTION Multidrug efflux pump Confers resistance to tetraphenylphosphonium ### SEQUENCE -M-T-Y-L-F-L-I-C-A-I-L-A-E-V-V-A-T-S-L-L-K-S-T-Q-G-F-T-R-L-W-P-T-V-I-C-L-L-G-Y-A-V-S-F-A-L-L-A-V-S-I-S-R-G-M-Q-T-D-V-A-Y-A-L-W-S-A-I-G-T-A-L-I-V-L-I-A-V-L-F-L-G-S-P-I-S-V-T-K-V-V-G-V-G-L-I-I-A-G-V-V-T-L-N-L-T-G-A-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-D-S-T-G-R-N-L-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-Q-K-L-G-I-P-A-I-R-I-P-L-H-G-R-I-E-V-D-H-P-Y-V-L-L-L-P-T-Y-G-G-G-R-A-T-P-D-L-N-A-G-G-Y-V-P-K-Q-V-I-A-F-L-N-N-E-H-N-R-S-L-I-R-G-V-I-A-A-G-N-N-N-F-G-A-E-F-A-Y-A-G-N-V-V-S-R-K-C-G-V-P-Y-L-Y-R-F-E-L-M-G-T-Q-D-D-V-D-A-V-R-A-G-L-A-E-F-W-K-E-Q-T-C-H-Q-P-S-L-Q-S-L"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-Q-I-S-R-D-E-V-A-H-L-A-R-L-S-R-L-A-L-T-D-A-E-L-D-S-F-A-G-Q-L-D-A-I-L-T-H-V-S-Q-V-Q-A-V-D-V-T-G-V-E-P-T-D-N-P-L-K-D-L-N-V-T-R-P-D-E-P-M-P-C-L-T-Q-A-E-A-L-A-E-A-P-E-A-V-D-G-R-F-A-V-P-Q-I-L-G-D-E"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-L-T-V-G-R-V-V-K-A-H-G-I-S-G-E-I-V-V-E-I-R-T-D-D-P-A-A-R-F-A-P-G-N-T-L-R-A-K-P-S-R-G-G-P-E-R-S-C-V-I-E-S-A-R-E-H-G-G-R-L-L-V-R-L-A-G-V-T-D-R-D-A-A-D-A-L-R-G-T-L-F-V-V-D-S-A-E-L-P-D-I-D-E-P-D-T-Y-Y-D-H-Q-L-E-G-L-Q-V-R-T-T-G-G-R-R-V-G-A-V-A-E-V-L-H-T-A-A-G-E-L-L-A-V-R-D-D-A-D-G-A-P-R-E-V-L-V-P-F-V-S-A-I-V-T-A-V-S-L-D-D-G-L-I-E-I-D-P-P-D-G-L-L-D-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-R-L-D-F-V-D-Q-A-S-L-R-D-D-I-P-V-F-G-P-G-D-T-V-N-V-H-V-K-V-I-E-G-A-K-E-R-I-Q-V-F-K-G-V-V-I-R-R-Q-G-G-G-V-R-E-T-F-T-V-R-K-E-S-Y-G-V-G-V-E-R-T-F-P-V-H-S-P-N-I-D-H-I-Q-V-V-T-R-G-D-V-R-R-A-K-L-Y-Y-L-R-E-L-R-G-K-K-A-K-I-K-E-K-R"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-T-G-L-P-S-Q-T-Q-V-I-E-L-L-G-G-E-F-A-R-A-G-Y-E-I-E-D-V-V-I-D-A-H-A-R-P-P-R-I-T-V-I-A-D-G-D-D-G-L-D-L-D-A-A-A-T-L-S-R-S-A-S-A-L-L-D-K-L-D-T-I-E-D-H-Y-V-L-E-V-S-S-P-G-V-D-R-P-L-R-T-P-K-H-F-R-R-A-R-G-R-K-V-D-V-V-L-S-D-N-S-T-V-T-G-R-V-G-E-T-G-D-D-T-I-A-L-V-V-R-A-G-R-D-W-A-I-R-E-I-P-L-G-D-V-V-K-A-V-V-Q-V-E-F-S-P-P-A-Q-A-E-L-E-L-A-G-V-G-G-T-D-K-T-E-E-R-R-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-D-P-A-R-A-R-R-L-A-K-R-I-N-T-I-V-A-S-A-I-E-F-E-I-K-D-P-G-L-D-G-V-T-I-V-D-T-K-V-T-A-D-L-H-D-A-T-V-F-Y-T-V-M-G-R-T-L-D-D-E-P-D-Y-G-A-A-A-A-A-L-E-R-A-K-G-A-L-R-T-M-V-G-A-G-T-G-V-R-F-T-P-T-L-T-F-T-R-D-T-T-S-D-S-V-A-R-M-D-E-L-L-A-R-A-R-A-A-D-A-D-L-A-R-V-R-S-G-A-K-P-A-G-E-A-D-P-Y-R-E-S-G-S-G-V-E-P-G-R-D-G-S-I-G-D-D-D-Q-P-E-Y"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-A-E-Q-K-K-E-I-L-G-T-Y-G-L-H-D-T-D-T-G-S-P-E-A-Q-V-A-L-L-T-K-R-I-A-D-L-T-E-H-L-K-V-H-K-H-D-H-H-S-R-R-G-L-L-L-L-V-G-R-R-R-R-L-L-K-Y-V-A-Q-I-D-V-E-R-Y-R-S-L-V-E-R-L-G-L-R-R"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-R-H-P-D-S-R-V-I-D-S-R-E-T-D-E-G-Q-A-I-R-R-R-R-S-C-P-E-C-G-R-R-F-T-T-V-E-T-A-V-L-A-V-V-K-R-S-G-V-T-E-P-F-S-R-E-K-V-I-S-G-V-R-R-A-C-Q-G-R-Q-V-D-D-D-A-L-N-L-L-A-Q-Q-V-E-D-T-V-R-A-A-G-S-P-E-V-P-S-H-E-V-G-L-A-I-L-G-P-L-R-D-L-D-E-V-A-Y-L-R-F-A-S-V-Y-R-S-F-E-S-A-D-D-F-E-R-E-I-Q-A-L-R-E-H-R-G-V-A-T-P-G"} +{"text": "### FUNCTION Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species in vitro, but may act as a sensor of peroxynitrite levels in vivo ### SEQUENCE -M-P-T-D-L-H-P-D-L-A-A-L-A-P-L-L-G-T-W-T-G-R-G-S-G-K-Y-P-T-I-Q-P-F-D-Y-L-E-E-V-T-F-S-H-V-G-K-P-F-L-A-Y-A-Q-K-T-R-A-A-A-D-G-K-P-L-H-A-E-T-G-Y-L-R-V-P-Q-P-G-R-L-E-L-V-L-A-H-P-S-G-I-T-E-I-E-V-G-S-Y-A-V-T-G-G-L-I-E-M-R-M-S-T-T-S-I-G-L-T-P-S-A-K-E-V-T-A-L-A-R-W-F-R-I-D-G-D-E-L-S-Y-S-V-Q-M-G-A-V-G-Q-P-L-Q-D-H-L-A-A-V-L-H-R-Q-R"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-N-N-K-K-D-E-Q-A-A-A-A-T-P-I-S-R-L-G-Y-E-A-C-R-D-E-L-I-E-V-V-R-Q-L-E-Q-G-G-L-D-L-D-A-S-L-N-L-W-E-R-G-E-Q-L-A-K-R-C-E-E-H-L-A-G-A-R-K-R-I-E-D-A-L-A-A-G-E-A-D-D-D"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-L-G-S-L-S-W-E-H-M-L-V-L-V-V-V-G-L-V-V-L-G-P-E-R-L-P-G-A-I-R-W-T-S-N-A-L-R-Q-A-R-D-Y-L-S-G-V-T-T-Q-L-R-E-D-L-G-P-E-F-D-D-L-R-V-P-L-S-E-L-Q-K-L-R-G-M-T-P-R-A-A-L-T-K-H-L-L-D-G-D-D-S-F-L-T-G-A-F-D-R-P-V-N-G-A-A-A-Q-P-P-P-A-P-A-P-P-P-E-P-H-R-S-G-Q-T-P-F-D-A-D-A-T"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-D-I-H-P-T-Y-A-E-T-T-V-L-C-G-C-G-N-T-F-Q-T-R-S-T-K-D-G-G-R-I-V-V-E-V-C-S-Q-C-H-P-F-Y-T-G-K-Q-K-I-L-D-S-G-G-R-V-A-R-F-E-K-R-Y-G-K-R-K-A-G-A-E-K-A-E-S-A-D-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-G-D-A-S-L-S-V-L-A-S-S-Q-V-V-A-E-G-G-N-N-F-L-V-P-N-G-T-F-F-F-V-L-A-I-F-L-I-V-L-A-V-I-G-T-F-V-V-P-P-V-M-K-V-L-R-E-R-D-A-M-V-A-K-T-A-A-D-N-R-K-A-A-E-Q-F-E-A-A-Q-A-D-Y-E-E-A-M-T-E-A-R-V-Q-A-S-S-L-R-D-N-A-R-A-E-G-R-K-V-V-E-D-A-R-A-K-A-E-Q-E-V-L-S-T-L-Q-L-A-A-R-Q-L-K-R-E-R-D-A-V-E-L-D-L-R-A-N-V-A-S-M-S-A-T-L-A-S-R-I-L-G-V-D-V-A-P-A-A-A-T-T-S-A-T-K-T-S-G-R"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-E-L-N-V-E-I-V-A-V-D-R-K-I-W-S-G-E-A-T-F-L-F-T-R-T-T-V-G-E-I-G-I-L-P-R-H-I-P-L-V-A-Q-L-V-D-D-A-M-V-R-V-E-R-E-G-E-D-D-L-R-I-A-V-D-G-G-F-L-S-V-T-E-E-T-V-T-I-L-A-E-S-A-E-F-S-S-E-I-D-E-S-A-A-R-E-A-A-E-S-D-D-P-R-V-A-A-R-G-R-A-R-L-R-A-V-G-A-I-D"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-V-V-M-S-A-P-T-E-P-K-S-R-P-G-T-T-G-Q-R-E-S-A-P-E-D-V-T-A-S-P-W-V-T-I-V-W-D-D-P-V-N-L-M-T-Y-V-T-Y-V-F-Q-K-L-F-G-Y-S-E-P-H-A-T-K-L-M-L-Q-V-H-N-E-G-K-A-V-V-S-A-G-S-R-E-A-M-E-V-D-V-S-K-L-H-A-A-G-L-W-A-T-M-Q-Q-D-R"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-G-I-V-G-V-G-I-D-L-V-S-I-P-E-F-A-E-Q-V-D-Q-P-G-T-V-F-S-E-T-F-T-P-G-E-R-R-D-A-S-D-K-S-S-S-A-A-R-H-L-A-A-R-W-A-A-K-E-A-V-I-K-A-W-S-G-S-R-F-A-Q-R-P-V-L-R-E-D-I-H-R-D-I-E-V-V-T-D-M-W-G-R-P-R-V-R-L-S-G-D-I-A-K-H-L-A-D-V-T-I-H-V-S-L-T-H-E-K-D-T-A-A-A-V-A-I-L-E-T-P"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-D-M-R-S-P-S-Q-G-L-N-L-T-D-S-V-Y-E-R-L-L-S-E-R-I-I-F-L-G-S-E-V-N-D-D-V-A-N-R-L-C-A-Q-I-L-L-L-A-A-E-D-P-T-K-D-I-S-L-Y-I-N-S-P-G-G-S-I-S-A-G-M-A-I-Y-D-T-M-V-L-A-P-C-D-I-A-T-Y-A-M-G-M-A-A-S-M-G-E-F-L-L-A-A-G-T-K-G-K-R-Y-A-L-P-H-A-R-I-L-M-H-Q-P-L-G-G-V-T-G-S-A-A-D-I-A-I-Q-A-E-Q-F-H-V-I-K-K-E-M-F-R-L-N-A-E-F-T-G-Q-S-I-E-R-I-E-A-D-S-D-R-D-R-W-F-T-A-Q-E-A-L-E-Y-G-F-V-D-H-I-I-T-R-A-A-T-I-T-N-G-E-A-Q"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-A-T-Y-A-I-V-K-T-G-G-K-Q-Y-K-V-A-V-G-D-V-V-K-V-E-K-L-D-S-E-P-G-S-N-V-S-L-P-V-A-L-V-V-D-G-A-K-V-T-S-D-A-A-A-L-A-K-V-A-V-T-G-E-V-L-E-H-T-K-G-P-K-I-R-I-H-K-F-R-N-K-T-G-Y-H-K-R-Q-G-H-R-Q-Q-L-T-V-L-K-V-T-G-I-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-Q-K-R-N-K-T-N-E-R-A-R-L-R-N-K-S-V-K-S-S-L-R-T-A-V-R-A-F-R-E-A-A-H-A-G-D-K-E-K-A-A-E-L-L-V-S-T-N-R-K-L-D-K-A-A-S-K-G-V-I-H-K-N-Q-A-A-N-K-K-S-A-L-A-Q-A-L-N-K-L"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-I-E-V-S-N-E-S-G-I-D-V-S-E-A-E-L-I-S-V-A-R-F-V-I-A-K-M-D-V-N-P-A-A-E-L-S-M-V-L-L-D-T-A-A-M-A-D-L-H-M-R-W-M-D-L-P-G-P-T-D-V-M-S-F-P-M-D-E-L-E-P-G-G-R-P-D-A-P-E-P-G-P-A-M-L-G-D-I-V-L-C-P-E-F-A-A-D-Q-A-A-A-A-G-H-S-L-G-H-E-L-A-L-L-T-I-H-G-V-L-H-L-L-G-Y-D-H-G-E-P-D-E-E-K-E-M-F-A-L-Q-D-R-L-L-E-E-W-V-A-D-Q-V-E-A-Y-H-Q-D-R-Q-Q-E-R-D-R-R-L-L-D-K-S-R-Y-F-D-H"} +{"text": "### FUNCTION Part of cytochrome c oxidase, its function is unknown ### SEQUENCE -M-H-I-E-A-R-L-F-E-F-I-A-G-F-F-F-L-T-A-L-L-Y-G-V-L-T-A-L-F-A-T-G-G-E-E-W-A-G-T-T-A-L-A-L-T-G-G-L-A-L-I-V-A-T-F-F-R-F-V-A-R-R-I-D-T-R-P-E-D-Y-E-G-A-E-I-S-D-G-A-G-E-L-G-F-F-S-P-H-S-W-W-P-I-L-I-A-L-S-G-S-V-A-A-V-G-I-A-L-W-L-P-W-L-I-V-A-G-V-M-F-I-L-S-S-V-A-G-L-V-F-E-Y-Y-L-G-P-E-K-H"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-L-S-P-W-H-W-A-I-L-A-V-V-V-I-L-L-F-G-A-K-K-L-P-D-A-A-R-S-L-G-K-S-M-R-I-F-K-S-E-L-R-E-M-Q-S-E-N-K-T-E-T-S-A-L-G-A-Q-S-E-S-S-A-A-N-P-T-P-V-Q-S-Q-R-V-D-P-P-A-P-S-E-Q-G-H-S-E-A-R-P-A-S"} +{"text": "### FUNCTION Acyl carrier protein involved in the formation of acyl-S-ACP intermediates within the mycobactin biosynthesis process ### SEQUENCE -M-P-A-G-S-P-E-N-H-V-S-A-E-L-L-G-I-L-R-D-D-L-N-V-D-V-S-R-V-T-P-D-A-R-L-V-D-D-V-G-L-D-S-V-A-F-A-V-G-M-V-A-I-E-E-R-L-G-V-T-L-T-E-E-E-L-L-S-C-E-T-V-G-D-L-Q-A-A-I-A-A-E-P-R-E-T-R-D-E"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-D-I-P-P-D-L-H-Y-T-A-E-H-E-W-V-R-R-S-G-D-D-T-V-R-V-G-I-T-D-F-A-Q-S-A-L-G-D-V-V-F-V-Q-L-P-E-V-G-A-Q-L-T-A-G-E-S-F-G-E-V-E-S-T-K-S-V-S-D-L-Y-A-P-V-S-G-T-V-T-A-V-N-T-D-L-E-G-S-P-Q-L-V-N-S-D-P-Y-G-A-G-W-L-L-D-V-Q-V-S-D-A-A-A-L-E-S-A-I-T-A-L-L-D-A-E-A-Y-R-G-T-L-T-E"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-T-R-S-K-S-T-T-E-T-T-R-A-A-R-Q-A-R-I-V-A-I-L-S-S-A-Q-V-R-S-Q-S-E-L-A-A-L-L-A-D-E-G-I-E-V-T-Q-A-T-L-S-R-D-L-E-E-L-G-A-V-K-L-R-G-A-D-G-G-V-G-V-Y-M-V-P-E-D-G-S-P-V-R-G-V-S-G-G-T-A-R-L-S-R-L-L-S-E-L-L-V-S-A-D-A-S-A-N-L-A-V-L-R-T-P-P-G-A-A-D-Y-L-A-S-A-I-D-R-A-A-L-P-Y-V-V-G-T-I-A-G-D-D-T-V-F-V-A-A-R-D-P-M-T-G-A-E-L-A-D-T-L-E-K-L-T"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-A-V-N-A-H-K-K-R-R-S-I-L-K-A-S-K-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-Q-L-H-S-L-N-Y-A-Y-R-D-R-R-A-R-K-G-E-F-R-K-L-W-I-S-R-I-N-A-A-A-R-A-N-D-I-T-Y-N-R-L-I-Q-G-L-K-A-A-G-V-E-V-D-R-K-N-L-A-D-I-A-I-A-D-P-A-A-F-T-A-L-V-D-V-A-R-A-A-L-P-E-D-V-N-A-P-S-D-S-G-E-A-A"} +{"text": "### FUNCTION Binds oxygen cooperatively with very high affinity because of a fast combination and a slow dissociation rate ### SEQUENCE -M-K-I-L-A-R-F-R-K-A-E-P-A-S-I-Y-D-R-I-G-G-H-E-A-L-E-V-V-V-E-N-F-Y-V-R-V-L-A-D-E-Q-L-S-G-F-F-T-G-T-N-M-N-R-L-K-G-K-Q-V-E-F-F-A-A-A-L-G-G-P-H-P-Y-T-G-A-P-M-K-Q-V-H-Q-G-R-G-I-T-M-H-H-F-G-L-V-A-G-H-L-A-D-A-L-T-A-A-G-V-P-S-E-T-V-S-E-I-L-G-A-I-A-P-L-A-P-E-I-A-T-G-E-A-G-K-V-T-V"} +{"text": "### FUNCTION Plays a role in nuclear translocation of the viral pre-integration complex ### SEQUENCE -M-A-D-P-R-K-T-V-P-P-G-N-G-G-E-V-T-I-G-E-A-F-A-W-L-E-R-M-V-E-A-I-N-R-E-A-V-N-H-L-P-R-E-L-I-F-Q-V-W-Q-R-S-W-R-Y-W-H-D-D-L-G-M-S-Q-S-Y-T-K-Y-R-Y-L-R-L-M-Q-Y-A-M-F-I-H-V-K-K-G-C-T-C-L-G-G-G-H-G-P-G-G-W-R-P-G-P-P-P-P-P-P-G-L-V"} +{"text": "### FUNCTION Stimulates gene expression driven by the HIV-2 LTR Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle Cell cycle arrest creates a favorable environment for maximizing viral expression and production ### SEQUENCE -M-T-E-A-P-A-E-F-P-P-E-D-E-T-P-P-R-G-P-G-D-E-W-V-I-G-I-L-R-E-L-R-E-E-A-L-K-H-F-D-P-R-L-L-T-T-L-G-N-Y-I-C-A-R-H-G-D-T-L-E-S-A-R-E-L-I-N-V-L-Q-R-A-L-F-V-H-F-R-A-G-C-K-I-S-R-I-G-Q-T-R-G-E-T-P-F-S-A-I-P-T-P-R-G-M-Q"} +{"text": "### FUNCTION Escorts unspliced or incompletely spliced viral pre-mRNAs ### SEQUENCE -M-N-G-R-A-D-E-E-G-L-Q-R-K-Q-R-L-I-R-L-L-H-Q-T-N-P-Y-P-Q-G-L-G-T-A-R-Q-R-R-N-R-R-R-R-R-K-Q-H-W-R-Q-L-V-A-L-A-N-S-I-Y-T-F-P-D-P-P-A-D-S-P-L-D-R-A-I-Q-R-L-Q-G-L-T-I-Q-E-L-P-D-P-P-T-N-L-P-E-S-S-E-S-T-N-N-N-Q-G-L-A-E-T-Y-N-S-L-P-A-I-W-V-R-V-D-P-R-S-A-P-G-P-C-K-D-Y-E-R-D-S-C-E-R-V-E-R-L-V-G-G-N-G-T-D-R-Q-G-N-T-C-S-S-K-K-D-Q-A-G-G-R-T-C-P-P-V-R-G-S-G-I-N-R-E-T-L"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-T-N-S-Q-S-D-A-A-L-A-A-V-L-D-R-F-D-P-S-A-G-G-P-G-A-Y-D-T-P-L-G-I-T-N-P-P-I-D-E-L-L-D-R-V-S-S-K-Y-A-L-V-I-Y-A-A-K-R-A-R-Q-I-N-D-Y-Y-N-Q-L-G-E-G-I-L-E-Y-V-G-P-L-V-E-P-G-L-Q-E-K-P-L-S-I-A-L-R-E-I-H-G-D-L-L-E-H-T-E-G-E"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-G-A-A-G-N-T-G-S-S-G-D-S-R-E-L-M-S-A-A-D-V-G-R-T-I-S-R-I-A-H-Q-I-I-E-K-T-A-L-D-G-P-D-G-P-R-V-V-L-L-G-I-P-T-R-G-V-T-L-A-D-R-L-A-R-N-I-G-E-Y-S-G-V-E-V-G-H-G-A-L-D-I-T-L-Y-R-D-D-L-M-Q-K-P-P-R-P-L-E-A-T-S-I-P-A-G-G-I-D-D-A-L-V-I-L-V-D-D-V-L-Y-S-G-R-S-V-R-S-A-L-D-A-L-R-D-V-G-R-P-R-V-V-Q-L-A-V-L-V-D-R-G-H-R-E-L-P-L-R-A-D-Y-V-G-K-N-V-P-T-S-R-S-E-S-V-H-V-L-L-A-E-H-D-G-A-D-G-V-V-I-S-R"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-K-P-L-R-G-R-H-Q-A-R-K-R-A-V-D-L-L-F-E-A-E-A-R-G-L-S-P-A-E-V-V-D-V-R-T-G-L-A-D-T-N-P-E-V-A-P-L-Q-P-Y-T-A-A-V-A-R-G-V-G-D-H-A-A-H-I-D-D-L-I-S-S-H-L-Q-G-W-T-L-D-R-L-P-A-V-D-R-A-I-L-R-V-A-V-W-E-L-L-Y-A-D-D-V-P-E-P-V-A-V-D-E-A-V-Q-L-A-K-E-L-S-T-D-D-S-P-G-F-V-N-G-V-L-G-Q-V-M-L-V-T-P-Q-I-R-A-A-A-R-A-V-R-G-P-R-D-T"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-T-A-D-F-K-N-G-L-V-L-V-I-D-G-Q-L-W-Q-I-V-E-F-Q-H-V-K-P-G-K-G-P-A-F-V-R-T-K-L-K-N-V-L-S-G-K-V-V-D-K-T-Y-N-A-G-V-K-V-E-T-A-T-V-D-R-R-D-T-T-Y-L-Y-R-D-G-S-D-F-V-F-M-D-S-Q-D-Y-E-Q-H-P-L-P-E-S-L-V-G-D-A-A-R-F-L-L-E-G-M-P-V-Q-V-A-F-H-N-G-S-P-L-Y-I-E-L-P-V-S-V-E-M-E-V-T-H-T-E-P-G-L-Q-G-D-R-S-S-A-G-T-K-P-A-T-V-E-T-G-A-E-I-Q-V-P-L-F-I-N-T-G-D-K-L-K-V-D-T-R-D-G-S-Y-L-G-R-V-N-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-V-L-T-Q-H-R-V-P-D-R-P-G-D-P-D-Q-D-P-G-R-G-R-R-L-G-I-D-V-G-S-V-R-I-G-V-A-C-S-D-P-D-A-V-L-A-T-P-V-E-T-V-R-R-D-R-S-G-K-H-L-R-R-L-A-A-L-V-T-E-L-G-A-V-E-V-V-V-G-L-P-R-T-L-A-D-R-T-G-T-S-A-L-D-A-I-D-L-A-D-Q-L-A-R-R-I-A-P-T-P-V-R-L-A-D-E-R-L-T-T-V-A-A-Q-R-S-L-R-A-A-G-V-R-A-K-E-Q-R-A-V-I-D-Q-A-A-A-V-A-I-L-Q-S-W-L-D-Q-R-R-A-A-T-R-E-A-G-D-G"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-D-A-G-E-A-T-P-V-A-E-L-I-A-S-L-T-R-Q-V-P-D-F-P-K-P-G-I-Q-F-K-D-L-T-P-L-F-A-E-A-T-A-M-T-A-V-T-G-A-L-A-R-H-A-S-G-A-D-L-V-A-G-I-D-S-R-G-F-L-V-A-A-A-V-A-D-R-L-H-T-G-V-L-A-I-R-K-G-G-K-L-P-P-P-V-H-A-E-R-Y-D-L-E-Y-G-S-A-T-L-E-I-P-A-D-G-I-D-L-R-G-R-R-I-V-I-I-D-D-V-L-A-T-G-G-T-L-A-A-A-A-R-L-L-R-R-T-G-A-T-V-T-A-A-A-V-V-F-E-L-G-A-L-G-G-R-A-A-L-A-P-L-P-V-H-S-L-T-C-Q"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-A-S-V-R-G-E-V-L-E-V-A-L-D-H-A-V-I-E-A-A-G-V-G-Y-R-V-N-A-T-P-S-T-L-S-T-L-R-T-G-T-Q-A-R-L-I-T-A-M-I-V-R-E-D-S-M-T-L-Y-G-F-T-D-A-E-T-R-D-L-F-L-T-L-L-S-V-S-G-V-G-P-R-L-A-M-A-T-L-A-V-H-D-A-G-A-L-R-Q-A-L-H-D-G-D-V-A-A-L-T-R-V-P-G-I-G-K-R-G-A-E-R-M-V-L-E-L-R-D-K-I-G-A-A-G-A-A-G-A-P-A-G-A-A-R-N-G-H-A-V-R-G-P-V-V-E-A-L-V-G-L-G-F-A-A-K-Q-A-E-E-A-T-D-K-V-L-A-A-E-P-E-A-G-T-S-G-A-L-R-A-A-L-S-L-L-G-K-S-R"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-A-E-P-L-L-V-V-G-L-G-N-P-G-D-N-Y-A-R-T-R-H-N-V-G-F-M-V-A-D-L-L-A-A-R-M-G-S-K-F-K-A-H-K-R-S-G-A-E-I-V-S-G-R-L-A-G-R-S-V-V-V-A-K-P-R-C-Y-M-N-E-S-G-R-Q-V-G-P-L-A-K-F-Y-S-V-P-P-G-D-I-I-V-I-H-D-D-L-D-L-D-F-G-R-I-R-L-K-I-G-G-G-E-G-G-H-N-G-L-R-S-V-A-N-A-L-G-S-K-D-F-Q-R-V-R-I-G-I-G-R-P-P-G-R-K-D-P-A-A-F-V-L-E-N-F-T-S-T-E-R-A-D-V-P-T-I-C-E-Q-A-A-D-A-T-E-L-L-I-E-L-G-L-E-P-A-Q-N-R-V-H-A-W"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-Q-P-G-P-G-G-D-M-S-A-L-L-A-Q-A-Q-Q-M-Q-Q-K-L-M-E-A-Q-Q-Q-L-A-N-A-E-V-H-G-Q-A-G-G-G-L-V-K-V-V-V-K-G-S-G-E-V-V-A-V-K-I-D-P-S-V-V-D-P-S-D-V-E-T-L-Q-D-L-V-V-G-A-M-A-D-A-S-K-Q-V-T-R-M-A-Q-E-R-L-G-S-L-A-G-G-F-G-A-P-P-G-Q-P-P-A-P-A-P-G-V"} +{"text": "### FUNCTION Involved in cell division ### SEQUENCE -M-P-K-S-K-V-R-K-K-N-D-F-T-V-S-A-V-S-R-T-P-V-K-V-K-V-G-P-S-S-V-W-F-V-A-L-F-I-G-L-M-L-I-G-L-V-W-L-M-V-F-Q-L-A-A-V-G-S-Q-A-P-T-A-L-N-W-M-A-Q-L-G-P-W-N-Y-A-I-A-F-A-F-M-I-T-G-L-L-L-T-M-R-W-H"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-P-Y-E-I-M-V-I-L-D-P-T-L-D-E-R-T-V-A-P-S-L-E-T-F-L-N-V-V-R-K-D-G-G-S-V-E-K-V-D-I-W-G-R-R-R-L-A-Y-E-I-A-K-H-A-E-G-I-Y-V-V-I-D-L-K-A-E-P-A-T-V-S-E-L-D-R-Q-L-S-L-N-E-S-V-L-R-T-K-V-M-R-T-D-K-H"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-I-L-T-A-D-V-D-H-L-G-A-V-G-D-T-V-E-V-K-D-G-Y-G-R-N-F-L-L-P-R-G-L-A-I-V-A-S-R-G-A-Q-K-Q-A-D-D-I-R-R-A-R-E-T-K-A-V-R-D-L-D-H-A-N-E-F-K-T-A-I-E-A-L-G-P-V-T-L-P-V-K-T-A-G-D-S-G-K-L-F-G-S-V-T-A-G-D-V-V-A-A-I-K-K-A-G-G-P-N-L-D-K-R-I-V-R-L-P-K-A-H-I-K-A-L-G-T-H-P-V-A-V-H-L-H-P-E-V-D-V-E-V-P-L-E-V-V-P-Q-S"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-K-S-N-K-R-R-P-A-P-E-K-P-V-K-A-R-K-C-V-F-C-A-K-K-D-Q-A-I-D-Y-K-D-T-A-L-L-R-T-Y-I-S-E-R-G-K-I-R-A-R-R-V-T-G-N-C-V-Q-H-Q-R-D-I-A-I-A-V-K-N-A-R-E-V-A-L-L-P-F-T-S-S-A-R"} +{"text": "### FUNCTION CRISPR ### SEQUENCE -M-R-E-L-Y-L-V-I-A-Y-D-T-P-D-D-R-R-R-A-R-L-A-K-L-L-K-G-F-G-E-R-R-Q-Y-S-V-F-E-A-R-L-T-R-E-Q-W-A-H-L-K-G-K-L-E-A-L-V-N-K-E-E-D-V-L-A-V-Y-F-L-P-P-E-A-V-G-R-T-W-R-I-G-H-E-G-L-K-R-L-E-D-P-D-F-V"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-P-E-E-I-A-T-L-A-G-G-C-F-W-C-T-E-A-A-F-K-L-L-R-G-V-L-E-V-V-P-G-Y-A-G-G-H-V-P-H-P-T-Y-E-E-V-C-T-G-T-T-G-H-R-E-A-V-Q-V-R-F-D-P-G-V-L-P-Y-A-D-L-L-R-Y-F-F-A-V-H-D-P-T-S-E-D-R-Q-G-P-D-V-G-P-Q-Y-S-P-A-I-F-Y-H-S-E-E-Q-K-R-V-A-E-A-V-M-R-E-L-A-P-L-Y-P-K-P-I-A-T-K-L-L-P-F-T-T-F-Y-P-A-E-A-Y-H-R-D-Y-F-A-R-H-P-E-A-P-Y-C-R-L-V-I-A-P-K-L-E-K-A-R-K-A-F-K-S-L-L-R-P"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-R-T-G-G-K-Q-Y-K-V-S-E-G-D-F-L-K-V-E-K-L-E-G-A-V-G-D-T-V-E-L-K-D-V-L-M-V-G-G-E-T-V-A-I-G-T-P-L-V-P-S-A-S-V-V-G-R-I-V-D-Q-G-K-D-K-K-I-L-V-F-K-S-K-R-R-K-N-F-R-K-M-Y-G-H-R-Q-P-R-T-V-L-K-I-E-K-I-N-A"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-L-R-V-L-W-V-G-K-T-Q-E-E-W-V-R-R-G-I-D-E-Y-A-G-R-V-R-R-Y-A-P-L-E-I-G-E-A-R-D-E-K-G-A-A-A-E-A-M-R-A-R-E-C-E-R-L-D-K-L-V-P-R-T-S-R-L-I-L-L-D-E-R-G-D-Q-L-T-S-P-E-F-A-A-Y-I-S-R-C-R-D-T-A-V-P-E-L-A-F-A-I-G-G-A-Y-G-F-A-D-E-F-R-R-R-A-D-R-V-I-A-L-S-R-M-T-F-T-H-Q-M-V-R-V-V-L-L-E-Q-I-Y-R-A-F-T-I-I-G-N-E-P-Y-H-H"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-S-R-I-V-S-V-G-I-S-E-F-K-I-A-S-A-P-T-I-L-M-T-Y-G-L-G-S-C-V-G-I-A-L-H-D-P-V-A-L-T-G-G-L-A-H-T-L-L-P-A-P-V-R-G-M-D-S-M-V-K-S-A-K-F-T-C-W-A-V-D-L-M-V-E-E-L-I-K-C-G-C-V-A-E-R-L-V-A-K-L-A-G-G-A-T-M-F-E-P-Q-H-R-T-T-H-S-G-I-G-E-R-N-V-T-A-A-K-E-A-L-E-R-R-G-I-P-L-V-A-S-D-T-G-D-D-Y-G-R-S-L-E-F-N-T-V-T-G-V-I-T-V-R-A-L-Q-R-P-I-K-R-M"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-E-G-I-H-P-K-Y-N-D-V-M-V-K-C-A-C-G-N-S-F-Q-T-R-S-T-K-T-E-I-S-T-E-I-C-S-A-C-H-P-F-F-T-G-K-Q-K-L-I-D-T-A-G-R-V-E-R-F-R-K-K-Y-G-M"} +{"text": "### FUNCTION Essential cell division protein ### SEQUENCE -M-A-Q-A-R-T-E-F-S-K-V-A-A-P-R-K-L-E-E-M-Y-A-Q-R-G-D-L-F-P-Y-L-L-A-V-L-V-L-L-T-L-V-S-V-F-H-V-W-S-R-V-R-V-V-D-L-N-L-E-V-A-E-V-A-R-Q-L-K-V-A-Q-E-E-Q-N-R-L-K-L-E-V-A-S-L-K-T-P-A-R-I-E-A-V-A-K-G-E-L-G-M-A-L-P-T-D-Q-Q-V-V-V-V-K"} +{"text": "### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-V-L-T-R-K-M-G-E-V-V-T-I-G-D-S-I-R-I-K-V-V-E-M-K-G-N-Q-V-R-L-G-I-E-A-P-N-D-M-R-I-Y-R-E-E-I-Y-I-K-V-Q-R-E-N-Q-I-A-A-S-W-S-L-A-D-L-E-K-A-V-T-C-L-G-A-D-G-K-E"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-N-V-T-T-T-R-F-G-E-I-A-V-E-E-A-K-I-I-T-L-P-D-G-M-L-G-F-S-E-K-R-F-V-L-L-T-P-Q-N-I-T-P-F-C-W-L-Q-S-V-E-N-P-E-L-A-F-V-V-V-D-T-K-E-C-A-S-D-Y-A-V-K-L-T-A-E-E-S-E-K-L-C-V-N-D-G-D-E-V-V-L-L-A-V-V-T-M-A-S-D-P-F-N-I-T-V-N-L-Q-G-P-I-A-L-N-P-K-R-M-L-A-K-Q-I-V-L-E-G-S-R-Y-T-T-K-H-P-F-F-D-Q-A-A-R-S-K-A-P-G-K-R-N-A-S-G-E-V-T-A-A"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-G-E-T-I-R-F-G-V-S-I-D-E-K-L-L-E-S-F-D-G-L-I-E-E-K-G-Y-M-N-R-S-E-A-I-R-D-L-I-R-A-A-L-V-E-L-K-W-E-V-G-D-E-E-T-V-G-T-V-T-L-V-Y-D-H-H-V-R-D-L-S-D-K-L-T-E-Q-Q-H-A-H-H-D-K-V-I-S-A-L-H-V-H-L-D-A-H-N-C-L-E-V-L-V-V-R-G-K-A-R-E-V-K-K-I-A-D-E-L-I-G-V-K-G-V-K-H-G-K-L-V-M-T-T-T-G-E-E-L-H"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-T-K-V-A-K-K-E-E-V-T-R-D-W-Y-L-V-D-A-D-N-K-V-L-G-R-M-A-T-E-I-A-N-I-L-R-G-K-K-K-P-I-Y-T-P-S-V-D-T-G-D-F-V-V-V-V-N-A-A-K-L-Q-L-T-G-N-K-L-A-D-K-M-Y-Y-H-H-T-G-F-P-G-G-I-K-S-I-T-A-G-K-L-I-E-K-K-P-E-D-L-I-R-K-A-V-K-G-M-L-P-K-N-K-L-A-R-H-M-L-K-K-L-K-V-Y-A-G-P-E-H-P-H-E-A-Q-Q-P-K-T-L-D-I"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-N-K-E-T-K-Q-Q-Q-V-A-E-L-H-D-K-L-Q-R-A-K-A-V-F-L-A-D-F-R-G-M-N-V-E-Q-A-T-T-L-R-N-E-L-R-S-A-A-V-E-Y-K-V-V-K-N-T-L-L-E-L-A-S-R-D-T-D-K-E-S-L-S-Q-H-F-A-G-P-T-A-I-A-L-S-Y-D-D-P-V-S-A-A-K-V-L-S-K-F-A-K-T-Q-P-N-T-F-K-L-K-A-G-V-L-T-G-K-A-I-S-V-A-D-I-Q-S-L-A-D-L-P-S-R-E-V-L-I-A-K-L-L-G-T-I-N-A-P-V-A-N-F-V-G-V-L-A-A-V-P-G-S-F-V-R-A-L-N-A-I-K-V-Q-K-E-G-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-E-I-T-K-A-D-V-I-S-F-I-E-N-M-T-V-L-E-L-A-E-L-V-K-E-L-E-D-K-F-G-V-S-A-A-A-P-V-A-V-A-A-A-A-A-P-A-A-A-A-E-A-A-E-E-K-T-E-F-D-V-I-L-K-S-A-G-A-N-K-I-G-V-I-K-V-V-R-A-L-T-G-L-G-L-K-E-A-K-D-L-V-D-G-A-P-K-P-V-K-N-G-V-S-K-E-E-A-E-E-A-K-K-Q-L-V-E-S-G-A-E-V-E-I-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-E-V-A-K-R-V-I-L-P-D-P-K-F-N-D-R-V-V-A-K-L-V-S-V-I-M-L-D-G-K-K-S-T-A-E-R-A-L-Y-G-A-L-D-I-V-S-Q-K-A-G-E-E-P-V-K-V-L-K-K-C-L-D-N-I-K-P-M-L-G-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-A-D-R-R-V-S-L-A-M-R-W-L-V-R-Y-A-N-E-R-S-E-K-T-I-T-D-K-L-A-G-E-I-L-D-A-Y-N-N-R-G-A-A-V-K-K-R-E-D-T-H-R-M-A-E-A-N-R-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-P-S-Q-K-I-R-I-R-L-K-A-F-D-H-K-L-L-D-Q-S-V-G-E-I-V-D-T-A-K-R-T-G-A-R-V-A-G-P-I-P-L-P-T-V-I-N-K-Y-C-V-L-R-G-P-H-V-D-K-K-S-R-E-Q-F-E-I-R-T-H-K-R-L-I-D-I-L-D-P-T-Q-Q-T-V-D-A-L-M-K-L-D-L-S-A-G-V-D-V-E-I-K-L"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-L-Y-D-V-I-K-K-P-L-I-T-E-K-T-T-I-E-K-D-S-K-N-V-V-S-F-E-V-D-R-D-A-N-K-I-E-I-K-E-A-V-E-K-L-F-K-V-E-V-A-E-V-N-T-V-N-V-A-G-K-V-K-R-F-G-R-H-Y-G-K-R-S-N-W-K-K-A-Y-V-T-L-K-E-G-S-S-V-D-F-F-E-I"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-I-K-K-G-P-F-V-D-D-H-V-A-K-K-V-A-A-E-S-A-G-S-K-K-V-I-K-T-W-S-R-R-S-T-I-T-P-D-F-I-G-L-T-F-A-V-H-N-G-K-K-F-I-P-V-F-V-T-E-N-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-H-G-H-A-A-D-K-K-S-K-L-K-K-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-S-A-K-L-T-F-A-R-L-S-P-R-K-T-R-L-V-V-D-M-V-R-G-K-G-I-Q-D-A-L-T-I-L-R-F-S-P-Q-A-S-A-K-L-V-S-K-L-L-R-S-A-V-A-N-A-E-Q-K-G-A-S-D-V-D-R-L-Y-V-K-S-I-S-V-D-G-G-P-V-L-K-R-F-V-P-R-A-M-G-R-A-S-K-I-R-K-P-T-S-H-I-T-V-V-L-A-D-K-Q"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-H-R-K-Q-M-K-G-R-M-K-G-D-A-Q-R-G-A-S-L-A-F-G-E-F-G-L-Q-A-T-E-C-G-W-V-D-S-R-Q-I-E-A-A-R-I-A-M-T-R-Y-I-K-R-G-G-K-I-W-I-R-L-F-P-D-K-P-L-T-S-K-P-A-E-T-R-M-G-K-G-K-G-S-P-D-S-W-V-C-V-V-K-P-G-K-V-L-Y-E-M-E-G-V-T-E-E-I-A-R-E-A-F-R-L-A-A-H-K-L-P-V-G-T-K-F-I-S-R-K-D-G-H-E-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-Q-R-G-N-R-K-T-Q-V-G-V-V-V-S-D-K-M-D-K-T-V-V-V-R-V-S-H-L-V-K-H-P-V-Y-N-K-Y-I-K-R-S-V-K-Y-K-A-H-D-T-D-N-S-C-K-T-G-D-R-V-L-I-V-E-T-R-P-L-S-K-D-K-R-W-K-V-R-Q-I-I-D-R-V-E"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-V-L-D-V-A-D-N-S-G-A-K-K-L-F-C-I-K-V-L-G-G-S-K-R-K-Y-A-G-V-G-D-I-V-V-C-S-V-R-E-A-V-P-N-A-K-V-K-K-G-D-V-V-K-V-V-I-V-R-T-A-K-E-I-G-R-P-D-G-S-Y-I-R-F-D-D-N-S-G-V-V-I-N-N-Q-R-E-P-V-G-T-R-I-F-G-P-V-A-R-E-L-R-A-Q-K-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-R-L-K-E-L-Y-H-K-E-I-V-E-Q-L-T-K-D-F-G-Y-S-N-V-M-Q-V-P-K-I-E-K-I-V-V-N-M-G-L-G-E-A-I-Q-N-V-K-I-L-D-S-A-V-E-E-L-A-A-I-A-G-Q-K-A-V-I-T-K-A-K-K-S-I-A-G-F-K-L-R-Q-G-M-P-I-G-C-M-V-T-L-R-R-E-K-M-Y-E-F-L-D-R-L-I-N-V-A-L-P-R-V-R-D-F-K-G-V-S-A-K-G-F-D-G-R-G-N-Y-S-L-G-V-K-E-Q-L-I-F-P-E-I-N-Y-D-K-I-D-K-I-K-G-L-N-I-T-I-V-T-S-A-K-T-D-E-E-S-R-A-L-L-K-H-L-G-M-P-F-R-H"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-S-M-I-I-K-A-Q-R-G-S-K-F-K-V-R-E-Y-N-R-C-P-L-C-G-R-P-R-A-Y-Y-R-K-F-D-M-C-R-I-C-L-R-K-L-A-S-A-G-Q-I-P-G-V-I-K-S-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-T-D-P-I-A-D-M-L-T-R-I-R-N-A-N-M-A-R-L-Q-K-V-D-I-P-S-S-N-L-K-V-N-L-A-N-V-L-K-A-E-G-F-I-K-N-Y-K-V-I-A-D-S-R-Q-G-V-L-R-V-Y-L-K-Y-I-D-E-K-D-P-V-I-N-E-I-K-R-V-S-K-P-G-S-R-V-Y-V-G-S-D-K-I-P-S-V-K-N-G-M-G-V-A-I-L-S-T-S-K-G-L-I-T-D-K-S-A-R-E-A-G-V-G-G-E-V-L-C-T-V-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-R-P-I-E-I-P-S-G-V-K-V-E-F-S-D-S-V-L-T-I-E-G-P-K-G-K-L-S-R-Q-V-M-D-G-V-S-L-E-I-T-P-S-S-I-E-V-K-R-A-D-D-G-L-K-A-R-S-A-H-G-L-T-R-T-L-V-N-N-M-V-V-G-V-T-K-G-F-E-R-A-L-E-I-N-G-V-G-Y-R-A-E-A-K-G-D-V-L-N-L-S-L-G-Y-S-H-P-I-N-Y-A-L-P-A-G-I-I-V-E-V-D-K-M-T-K-L-V-V-K-G-I-D-K-E-L-V-G-Q-T-A-A-K-I-R-S-F-R-G-P-E-P-Y-K-G-K-G-I-K-Y-A-D-E-K-I-L-R-K-A-G-K-T-G-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-P-L-A-Q-K-K-V-A-H-L-K-R-K-T-R-V-R-K-K-I-R-G-T-T-E-R-P-R-L-N-V-F-K-S-A-Q-H-I-Y-A-Q-I-I-D-D-T-T-G-T-T-L-V-S-A-S-T-V-Q-K-E-A-S-E-S-L-N-H-C-G-N-V-E-A-A-K-R-V-G-A-L-I-A-K-R-A-L-E-K-N-I-A-T-V-V-F-D-R-N-G-F-L-Y-H-G-R-I-K-A-L-A-D-S-A-R-E-N-G-L-T-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-Y-K-I-N-P-N-D-L-N-L-T-D-K-V-V-H-I-S-R-V-A-K-V-V-K-G-G-R-R-F-S-F-S-A-L-V-V-V-G-D-G-N-G-C-V-G-Y-G-L-G-K-A-N-E-V-P-E-A-I-R-K-G-V-E-Q-A-K-K-N-L-I-K-V-P-I-V-E-G-H-T-I-P-Y-E-V-L-G-H-F-G-A-G-R-V-L-I-K-P-A-S-A-G-T-G-V-I-A-G-G-A-A-R-A-V-F-E-A-A-G-L-H-N-V-L-S-K-C-L-G-S-N-N-P-H-N-V-V-K-A-A-F-N-G-L-A-Q-L-R-S-P-E-E-I-M-A-R-R-G-V-T-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-L-N-E-L-R-P-A-V-G-A-T-K-D-R-K-R-I-G-R-G-P-G-S-G-H-G-K-T-A-T-K-G-H-K-G-Q-K-A-R-S-G-G-S-V-K-P-G-F-E-G-G-Q-M-P-M-Q-R-R-L-P-K-R-G-F-T-P-L-T-R-K-E-Y-A-L-V-N-V-G-Q-L-E-V-F-E-A-G-S-C-I-D-V-E-A-L-L-N-A-G-L-I-G-G-V-K-D-G-L-K-V-L-A-D-G-D-L-T-K-P-L-T-V-K-A-H-K-F-S-A-K-A-K-E-K-I-A-A-A-G-G-T-V-E-E-I-S-L"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-D-L-P-R-N-K-R-I-E-I-A-L-T-Y-I-F-G-I-G-R-T-T-A-Q-R-I-L-A-E-T-G-V-S-A-D-T-R-T-D-N-L-A-E-S-E-V-A-K-I-R-D-Y-I-D-K-N-L-K-V-E-G-D-L-R-R-D-V-S-M-D-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-K-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-A-R-T-V-A-G-K-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-S-P-S-K-K-V-V-R-K-K-K-E-K-K-N-I-P-N-G-V-A-H-I-Q-A-T-F-N-N-T-I-I-T-I-T-D-P-V-G-N-V-V-A-W-S-S-A-G-S-K-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-I-A-A-E-E-C-A-R-K-A-Q-E-H-G-M-R-S-V-E-V-F-V-K-G-P-G-S-G-R-E-S-A-L-R-A-L-Q-A-A-G-F-H-V-N-F-I-R-D-V-T-P-I-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-F-K-E-F-K-E-F-A-M-K-G-N-V-V-D-L-A-I-G-V-I-I-G-G-A-F-G-K-I-V-T-S-V-V-N-D-I-V-M-P-P-I-G-L-L-M-G-K-M-D-F-S-N-L-F-I-D-L-S-G-K-G-Y-E-S-L-K-A-A-K-D-A-G-A-P-V-I-S-Y-G-A-F-I-N-T-V-L-D-F-V-I-V-A-F-V-I-F-L-V-I-K-Q-I-N-R-L-K-K-E-P-V-P-A-P-P-D-T-K-E-C-A-F-C-C-S-A-I-P-I-K-A-T-R-C-P-H-C-T-S-E-Q-K"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-K-E-L-K-P-A-I-L-M-L-I-I-F-T-I-L-C-G-G-I-Y-P-A-V-V-T-G-I-A-Q-A-V-F-P-K-Q-A-K-G-S-L-I-T-D-A-R-G-R-E-V-G-S-T-L-I-G-Q-P-F-S-G-P-K-Y-F-W-P-R-P-S-A-T-P-E-F-G-Y-N-P-A-G-S-G-G-S-N-A-G-P-A-N-P-A-Y-L-K-T-V-G-E-R-I-K-A-L-R-D-A-G-I-K-G-S-I-P-A-D-L-V-Q-A-S-A-S-G-L-D-P-H-I-S-P-E-A-A-K-V-Q-I-P-R-V-A-R-A-R-G-M-S-A-G-A-L-S-R-L-I-A-A-H-T-E-D-R-Q-L-G-F-L-G-E-P-R-I-N-V-L-A-L-N-L-A-L-D-T-L-M-P"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-K-V-A-I-T-N-R-Q-K-R-H-P-I-G-T-R-R-L-R-K-V-A-E-T-I-L-G-A-L-G-Y-P-D-S-E-L-S-V-V-I-T-G-D-L-G-I-R-R-V-N-R-D-Y-L-G-K-D-R-P-T-N-V-I-S-F-A-M-G-E-G-D-F-G-D-L-N-P-D-V-L-G-D-V-I-I-S-A-D-T-A-A-R-E-A-E-E-A-G-I-A-F-W-S-R-L-C-F-L-L-L-H-G-T-L-H-I-T-G-Y-D-H-E-R-S-G-E-A-E-A-R-R-M-E-A-K-E-R-E-I-F-A-L-L-E-N-G-G-L-V"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-C-L-D-K-V-D-N-R-F-L-L-V-M-L-A-S-K-R-V-K-Q-L-Y-K-G-A-R-P-L-I-D-N-R-G-A-N-K-N-V-V-I-S-L-R-E-I-A-A-G-K-V-G-Y-E-L-T-S-R-R-S-R"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-H-H-K-S-A-L-K-R-I-K-Q-N-K-K-K-Y-L-R-N-K-H-I-R-S-T-L-R-T-F-I-K-R-V-R-E-A-V-E-A-K-N-A-D-Q-A-R-Q-A-L-L-A-A-I-P-V-I-D-K-A-A-S-K-G-V-I-H-A-S-N-A-S-R-N-V-S-R-L-T-K-L-V-N-T-L-G"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-F-G-T-G-I-D-I-V-D-I-T-R-F-D-R-L-V-E-E-G-N-V-R-L-F-E-R-L-F-T-P-H-E-M-E-Y-C-A-G-K-A-R-S-S-Q-H-Y-A-L-R-F-A-A-K-E-A-F-L-K-A-C-G-L-G-L-R-E-G-M-T-W-H-D-V-E-V-V-N-D-T-L-G-K-P-E-L-K-L-H-G-K-A-L-K-L-A-T-D-L-S-L-S-R-T-F-V-S-L-S-H-D-G-A-Y-A-V-A-L-V-V-L-E-R-P"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-V-E-K-F-E-T-A-L-K-K-L-E-D-V-V-R-K-L-E-G-G-D-L-S-L-D-D-S-L-K-A-F-E-E-G-V-K-M-A-S-F-C-T-K-K-L-D-E-A-E-K-K-V-E-L-L-L-K-K-K-D-G-T-F-V-R-E-D-F-R-L-D-D-E"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-Y-T-V-A-D-L-K-K-G-L-K-L-T-L-D-G-A-P-Y-L-V-I-A-F-E-F-S-K-P-G-K-G-Q-A-L-Y-R-T-K-M-R-N-M-I-T-G-V-I-L-D-R-T-Y-R-S-G-E-T-F-E-P-A-R-L-E-E-R-R-M-Q-Y-L-Y-K-E-D-T-H-Y-T-F-M-D-N-Q-T-F-E-Q-V-Q-M-D-E-D-A-V-G-D-A-K-N-F-L-I-D-N-L-E-V-D-I-L-L-F-G-E-K-A-I-G-V-T-L-P-N-F-V-N-L-R-V-V-Q-T-D-P-W-V-K-G-D-T-S-G-S-D-S-K-P-A-T-V-E-T-G-Y-I-L-R-V-P-P-F-I-E-E-G-E-M-I-V-I-D-T-R-S-G-E-Y-S-T-R-V-K-G"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-G-E-K-L-I-C-N-N-K-K-A-F-H-D-F-F-I-E-E-R-F-E-A-G-M-V-L-K-G-T-E-V-K-S-L-R-D-G-K-A-N-L-N-D-S-F-A-L-I-R-N-G-E-I-F-L-H-N-L-H-I-N-P-Y-A-F-G-N-R-E-N-H-D-P-D-R-L-R-K-L-L-M-H-K-K-E-I-E-K-L-F-G-K-I-R-E-K-G-Y-S-V-V-P-L-R-L-Y-F-K-N-G-L-A-K-V-E-L-G-L-A-K-G-K-K-L-Y-D-K-R-E-D-M-K-K-K-D-Q-S-R-E-M-A-Q-A-L-R-E-K-S-K-S-H"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-G-A-R-R-L-G-R-E-L-A-L-Q-M-L-Y-S-R-D-Y-A-A-G-E-A-A-P-L-L-E-L-V-L-D-E-S-E-P-G-A-A-A-G-R-S-F-A-D-D-L-V-R-G-V-L-E-H-R-Q-E-I-D-T-A-I-T-G-A-S-K-N-W-S-I-G-R-M-A-R-V-D-L-S-I-L-R-M-A-M-Y-E-L-L-F-R-S-D-I-P-K-N-V-T-I-N-E-A-I-E-V-A-K-K-F-G-T-E-D-S-P-A-F-I-N-G-I-L-D-E-I-A-S-T-L-P-D-K-G"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-F-C-G-Q-L-D-S-K-V-V-D-S-R-P-D-K-G-G-A-A-I-R-R-R-R-E-C-E-S-C-G-K-R-F-T-T-H-E-R-I-E-E-V-L-P-L-V-L-K-K-D-G-R-R-E-P-F-D-R-L-K-L-I-A-G-I-Q-K-A-C-E-K-R-Q-V-S-R-E-T-I-E-R-L-V-D-R-L-E-A-R-L-P-E-L-G-E-K-E-V-P-S-T-T-I-G-E-W-V-M-T-E-L-H-D-I-D-E-V-A-Y-V-R-F-A-S-V-Y-R-S-F-K-D-V-N-E-F-M-S-E-L-Q-D-L-L-K-K"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-S-I-E-K-R-V-K-E-I-V-A-E-Q-L-G-V-D-E-A-Q-V-T-N-D-A-S-F-M-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-I-E-I-S-D-E-D-A-E-K-I-Q-N-V-Q-D-A-I-D-Y-I-T-E-H-T"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-L-V-T-D-K-K-K-E-I-I-T-T-H-K-L-H-D-S-D-T-G-S-P-E-V-Q-I-A-L-L-T-E-R-I-I-Y-L-T-E-H-F-K-V-H-K-K-D-H-H-S-R-R-G-L-L-K-I-V-G-Q-R-R-R-L-L-D-Y-L-K-K-K-D-V-E-R-Y-R-S-I-I-E-K-L-G-I-R-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-F-N-R-S-E-K-V-A-E-A-I-H-E-L-V-S-G-L-I-V-K-G-M-K-D-P-R-I-G-F-I-T-I-T-G-V-K-V-T-D-D-I-R-Q-A-T-I-Y-Y-T-V-M-G-D-D-E-A-R-V-S-T-A-R-G-L-A-S-A-T-G-F-L-R-R-E-I-G-K-Q-L-R-L-K-F-A-P-E-L-H-F-K-Y-D-Q-S-I-E-Y-G-N-R-I-D-Q-L-L-K-E-I-E-T-E-K-G-S-D-D"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-Q-K-D-D-V-A-G-R-I-T-A-V-A-E-Q-V-L-T-P-Q-G-L-E-L-V-E-V-E-Y-K-R-E-G-R-Q-M-V-L-R-L-F-V-D-K-P-G-G-I-S-L-D-D-C-A-A-V-S-R-E-L-S-E-I-L-D-V-E-D-F-I-R-E-N-Y-T-L-E-V-S-S-P-G-L-N-R-P-L-K-K-E-A-D-Y-E-R-Y-A-G-R-L-V-K-V-R-T-F-E-L-L-A-D-E-E-G-N-R-R-K-T-F-L-G-D-L-V-G-L-S-D-G-V-V-T-L-T-L-R-E-G-Q-L-A-R-I-P-L-D-K-I-A-K-A-N-L-E-F-E-F"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-F-K-A-R-R-R-R-N-K-V-L-K-L-A-K-G-F-R-G-A-R-S-K-L-F-R-S-A-T-E-A-V-D-R-A-L-N-Y-A-F-R-D-R-K-V-K-K-R-D-F-R-A-L-W-I-T-R-I-N-A-A-S-R-L-N-G-L-S-Y-S-K-L-I-H-G-L-K-Q-A-Q-V-E-I-D-R-K-V-L-A-D-L-A-V-S-D-P-K-G-F-S-E-I-A-T-L-A-K-A-Q-F"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-A-K-P-T-V-N-I-N-Q-A-I-R-A-R-E-V-R-V-V-G-A-D-S-E-Q-L-G-I-M-S-L-Q-E-A-L-A-L-A-E-A-R-Q-L-D-L-V-E-V-S-P-T-A-V-P-P-V-C-R-I-M-D-Y-G-K-F-K-Y-Q-Q-S-K-K-L-Q-E-A-R-K-K-Q-S-H-V-Q-V-K-E-V-K-L-R-P-K-T-D-E-H-D-L-M-T-K-I-K-H-V-R-R-F-I-E-E-G-N-K-A-K-V-T-L-V-F-R-G-R-E-I-T-H-L-E-F-G-S-R-A-L-D-R-V-A-A-E-L-E-D-I-A-V-V-E-F-K-P-K-M-E-G-R-S-M-F-M-I-V-A-P-K-V-K-K"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-A-D-G-T-V-I-L-D-T-A-G-V-K-R-A-L-T-R-I-A-H-E-I-L-E-R-N-K-G-V-D-G-L-V-L-V-G-I-R-T-G-G-V-H-L-A-R-E-I-V-A-R-L-E-E-I-E-G-A-T-V-P-V-G-E-V-D-I-T-L-Y-R-D-D-F-K-G-H-A-P-H-L-P-V-G-K-T-D-I-P-F-S-L-E-T-K-R-V-V-L-V-D-D-V-L-F-T-G-R-T-I-R-A-A-M-D-A-I-M-D-H-G-R-P-A-C-I-Q-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-F-V-G-R-N-V-P-T-S-L-K-E-K-I-A-V-L-F-D-A-A-N-R-P-T-D-V-V-L-E-K"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-I-T-T-L-T-C-P-R-C-R-A-E-T-V-W-E-G-N-P-H-R-P-F-C-S-A-R-C-K-T-V-D-L-A-A-W-A-D-E-E-Y-R-I-A-G-P-E-A-P-S-D-N-D-E-N-D-R-E"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-T-A-R-H-P-K-L-P-H-V-Y-L-K-P-G-E-F-H-F-A-T-K-P-T-V-V-T-T-V-L-G-S-C-V-S-V-T-M-F-D-V-F-S-R-T-A-A-I-C-H-A-L-L-P-D-G-P-R-D-D-V-F-R-Y-V-D-S-S-I-I-R-M-L-E-M-F-M-S-R-G-I-T-P-R-Q-L-Q-V-K-L-F-G-G-S-D-M-L-G-A-T-A-S-R-P-G-V-G-S-R-N-V-D-I-A-R-Q-V-L-A-A-E-G-L-E-V-A-A-A-D-V-G-G-T-R-G-R-K-L-F-F-Y-T-H-T-G-E-V-L-L-K-R-L-N-R-T-E-A-D-S"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-A-L-L-T-G-R-L-A-H-K-S-P-D-A-I-I-I-D-V-N-G-V-G-Y-R-V-Q-I-P-F-S-T-Y-Y-E-L-P-E-E-G-K-T-V-S-L-S-I-H-T-H-V-K-E-D-S-I-S-L-F-G-F-R-T-L-A-E-K-E-F-F-Q-L-L-I-S-V-S-G-I-G-P-K-M-A-R-D-I-L-S-N-I-Q-P-E-E-L-A-A-A-I-V-Q-G-N-L-V-R-L-S-S-I-P-G-I-G-K-K-T-A-E-R-L-V-L-E-L-K-E-K-V-R-K-M-D-V-A-P-S-A-Q-E-A-P-S-S-E-A-P-A-E-V-A-D-D-V-A-S-A-L-V-N-L-G-Y-K-E-A-V-V-R-K-V-L-A-E-M-S-I-E-P-D-A-S-T-E-A-V-L-R-Q-A-L-K-V-L-M-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-K-E-N-V-E-N-L-G-H-I-G-D-I-V-K-V-A-P-G-Y-A-R-N-Y-L-I-P-R-N-F-A-I-E-A-T-E-K-N-A-K-A-L-E-H-A-K-R-Q-L-E-Y-K-R-N-K-V-L-E-Q-A-R-L-L-V-A-K-I-E-G-L-S-L-S-I-S-H-Q-A-G-E-E-G-K-L-F-G-S-V-T-N-M-E-L-A-E-L-L-K-A-Q-G-V-E-I-D-R-K-K-I-V-L-A-E-P-I-K-H-V-G-E-F-T-A-V-V-K-V-H-P-E-V-A-A-N-L-K-V-V-V-T-K-A-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-E-E-R-T-E-R-P-E-R-T-E-R-P-E-R-P-Q-Q-R-G-S-G-P-R-K-R-R-P-F-Q-R-R-K-V-C-R-F-C-A-D-K-T-L-V-I-D-Y-K-D-P-R-V-L-R-S-F-I-T-E-R-G-K-I-V-P-R-R-I-S-G-N-C-S-A-H-Q-R-E-I-T-E-A-I-K-R-A-R-N-I-A-L-I-P-I-A-S-T-H-V-I-A"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-V-R-M-Y-E-T-I-V-I-V-Q-P-E-L-G-D-D-E-L-K-G-L-T-A-K-V-T-D-I-I-G-S-F-K-G-V-L-H-R-L-E-D-W-G-V-R-K-L-A-Y-P-V-K-K-S-V-R-G-R-Y-Y-Y-V-R-F-D-G-D-A-P-L-I-A-E-L-E-R-R-L-R-L-D-D-K-V-L-R-Y-Q-S-V-K-L-E-K-E-A-A-A-P-A-P-K-A-A-P-V-E-S-A-P-A-V-E-A-E"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-A-T-K-L-I-V-G-L-G-N-P-G-P-K-Y-L-W-T-R-H-N-A-G-F-M-V-L-D-R-L-A-H-A-I-G-A-S-V-T-R-K-S-F-S-G-V-F-G-E-G-A-W-H-G-E-R-L-L-L-L-K-P-Q-T-Y-M-N-L-S-G-R-S-V-A-E-A-L-R-F-H-K-L-P-L-C-D-T-I-V-I-H-D-D-L-D-I-P-F-G-R-V-K-V-K-E-G-G-G-H-G-G-H-N-G-L-R-S-L-V-Q-E-L-G-G-A-G-F-V-R-V-R-V-G-I-G-R-P-V-H-G-D-V-V-N-Y-V-L-T-N-F-S-Q-D-E-M-A-D-L-A-H-L-L-D-G-T-L-D-L-L-E-S-L-L-T-A-G-L-P-K-T-M-S-L-Y-N-N-K-D-L-L-A-P"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-E-Q-K-T-M-S-I-E-L-R-E-K-N-G-K-G-V-A-R-K-L-R-A-Q-D-V-V-P-G-V-V-Y-G-K-G-I-E-P-V-S-V-K-V-A-A-K-D-L-A-A-T-I-A-G-E-G-G-L-N-S-L-I-T-L-S-G-G-G-S-L-N-G-N-I-V-I-V-A-D-M-Q-R-N-P-L-K-G-D-I-L-H-V-D-F-H-R-I-S-L-D-E-K-V-K-V-H-V-P-L-V-M-V-G-T-A-A-G-V-K-E-G-G-M-L-D-V-V-T-Y-S-L-D-V-E-C-L-P-T-A-I-P-E-A-I-N-V-D-V-T-N-L-A-I-G-H-S-I-H-V-S-E-L-V-L-P-A-G-I-K-V-L-N-D-P-E-T-P-I-V-S-I-H-G-K-A-K-E-E-A-P-A-A-E"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-K-I-D-A-I-E-L-E-Q-M-K-K-N-I-P-P-F-K-P-G-D-T-L-K-V-H-V-K-I-V-E-G-D-K-S-R-I-Q-A-F-Q-G-V-C-I-S-R-Q-N-G-G-I-R-E-S-F-T-V-R-K-I-S-N-N-I-G-V-E-R-V-F-P-L-H-S-P-T-V-D-A-I-E-V-I-T-R-G-H-V-R-R-A-K-L-Y-Y-L-R-K-L-R-G-K-A-A-R-I-R-E-K-K-Y-V-A-A-Q"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-R-Q-D-D-L-K-L-L-G-K-I-V-T-T-H-G-I-R-G-Q-L-K-V-A-S-F-S-G-E-F-D-T-I-L-S-L-E-T-V-V-L-K-G-K-D-G-R-M-E-T-F-P-V-A-R-A-T-V-H-H-D-R-V-L-L-S-L-T-P-F-T-N-I-N-E-V-L-H-L-I-S-A-V-S-Y-A-H-R-D-Q-F-P-P-L-E-E-G-E-Y-Y-W-C-D-L-I-G-L-Q-V-V-T-A-A-G-T-V-I-G-R-L-D-S-I-L-P-T-E-S-H-D-V-Y-V-V-R-G-A-D-R-E-Y-L-I-P-A-V-E-D-V-V-V-Q-V-D-L-E-A-G-T-M-T-V-S-P-P-E-G-L-L-D-L"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-L-T-T-S-D-F-K-R-G-L-V-I-K-L-D-N-S-P-C-L-I-L-D-V-H-F-Q-S-P-S-A-R-G-A-S-T-M-V-K-T-R-Y-R-N-L-L-T-G-Q-V-L-D-K-T-F-R-S-G-D-K-V-E-E-A-D-F-E-R-H-K-G-Q-Y-L-Y-A-D-G-D-R-G-V-F-M-D-M-E-T-Y-E-Q-F-E-M-D-A-E-S-F-Q-V-I-Q-P-Y-L-L-D-G-T-E-V-V-L-G-L-F-Q-E-R-L-V-S-V-D-P-P-Q-V-V-E-L-T-I-T-D-T-P-P-V-I-K-N-A-T-A-T-A-Q-T-K-E-A-T-L-E-T-G-L-T-L-Q-V-P-P-Y-L-E-V-G-E-K-I-K-V-D-T-R-D-C-R-F-I-S-R-A"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-M-S-I-T-Q-N-V-V-E-I-C-E-K-S-A-E-G-R-R-I-L-A-V-V-L-E-I-G-E-L-S-G-V-V-P-E-A-V-E-F-C-F-E-A-C-T-A-G-T-L-A-E-G-A-R-L-A-I-D-R-V-P-G-R-G-E-C-G-N-C-A-T-V-F-P-V-R-T-Y-F-D-P-C-P-A-C-G-A-Y-G-V-R-V-V-A-G-E-E-L-R-V-K-E-L-E-V-E"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur , and thus conserves the redox energy in a proton gradient ### SEQUENCE -M-A-E-N-N-R-A-V-I-K-L-K-E-K-F-A-A-S-I-L-D-V-R-E-F-R-G-E-V-T-V-T-V-A-R-E-K-V-V-D-I-C-R-F-L-K-E-S-L-Q-Y-N-L-C-T-D-V-T-A-V-D-Y-L-G-K-Q-E-P-R-F-M-V-V-Y-N-L-Y-S-I-P-N-K-D-R-L-R-L-K-A-G-V-P-D-A-D-C-S-I-D-T-V-S-C-V-W-N-S-A-N-W-L-E-R-E-V-Y-D-L-M-G-V-Q-F-N-N-H-P-D-L-R-R-I-L-M-T-D-D-W-V-G-H-P-L-R-K-D-Y-P-L-Q-G-P-D-R-E-P-Y-K-G-R-L-S"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-I-S-N-A-I-A-R-R-Y-A-K-A-L-V-Q-L-G-A-E-E-G-A-V-D-R-F-G-V-E-L-G-Q-F-T-A-L-L-D-G-N-A-D-L-A-S-V-L-K-S-P-A-Y-R-I-E-A-K-R-E-I-L-R-D-V-L-A-K-L-N-L-S-G-T-V-S-N-F-L-Q-V-L-L-D-R-G-R-I-G-F-T-P-Q-I-A-H-S-Y-A-V-F-A-D-E-L-S-G-I-V-R-P-V-L-T-S-A-F-P-L-D-D-A-Q-V-E-G-M-K-S-A-L-A-K-A-T-G-K-R-V-E-L-S-A-Q-V-D-S-A-L-I-G-G-V-V-T-K-I-G-D-K-V-F-D-G-S-V-R-T-Q-L-N-R-I-Q-D-I-L-Q-K-G"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-V-H-F-S-D-S-L-S-R-L-L-A-E-L-Q-K-L-P-G-V-G-E-K-T-A-L-R-L-A-F-H-L-L-K-S-P-D-N-A-A-A-L-A-D-S-L-R-D-V-M-S-R-V-R-F-C-S-V-C-F-G-I-T-E-D-D-P-C-R-F-C-S-D-A-R-D-D-G-A-I-C-V-V-E-E-P-Q-D-L-L-A-V-E-R-T-R-A-F-R-G-R-Y-H-V-L-Q-G-A-L-S-P-L-N-G-V-T-P-D-R-L-R-V-A-E-L-M-K-R-L-E-G-G-G-V-R-E-V-V-I-A-T-N-F-T-V-E-G-E-A-T-A-L-Y-L-A-R-M-I-K-P-L-G-V-R-V-T-R-L-A-H-G-I-P-L-G-S-D-L-E-F-V-D-A-A-T-V-Q-R-A-L-E-G-R-S-E-L"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-E-H-L-Y-I-V-S-Y-D-I-R-N-Q-R-R-W-R-R-L-F-K-T-M-H-G-F-G-C-W-L-Q-L-S-V-F-Q-C-R-L-D-R-I-R-I-I-K-M-E-A-A-I-N-E-I-V-N-H-A-E-D-H-V-L-I-L-D-L-G-P-A-E-N-V-K-P-K-V-S-S-I-G-K-T-F-D-P-I-L-R-Q-A-V-I-V"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-D-K-K-K-H-G-T-V-Q-S-A-D-E-T-I-A-A-A-G-F-A-G-E-A-A-Q-G-K-G-E-D-V-Q-S-V-A-A-E-E-R-I-R-Q-L-E-T-E-L-A-A-K-E-A-E-A-A-A-N-W-D-K-F-V-R-E-R-A-D-L-E-N-Y-R-R-R-T-Q-K-E-K-E-E-L-L-K-Y-G-N-E-S-L-L-Q-D-I-L-P-V-V-D-S-M-E-R-A-L-G-H-A-D-S-E-S-L-S-A-V-I-E-G-I-R-M-T-H-G-M-L-L-G-T-L-K-K-F-G-V-V-A-V-E-A-E-R-G-T-V-F-D-P-A-Y-H-Q-A-M-C-Q-V-E-V-S-E-L-P-P-N-T-V-V-E-V-F-Q-R-G-Y-L-L-N-E-R-L-L-R-P-A-M-V-S-V-A-T-V-P-K-D-A-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-R-K-S-Y-R-V-K-T-E-R-D-F-Q-K-V-F-K-E-G-Q-S-M-A-N-R-G-F-V-V-Y-T-L-P-K-E-N-Q-K-H-F-R-V-G-I-S-V-G-K-K-V-G-H-T-A-V-A-R-N-R-L-K-R-F-I-R-A-T-L-T-E-L-K-P-E-I-R-P-D-L-D-F-L-V-I-A-R-P-Y-A-R-D-F-D-M-G-R-T-K-K-N-L-I-H-V-L-R-L-A-K-V-L-S-S-E-E-T-E-I-E-E-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-Q-A-I-E-L-K-K-G-M-I-F-N-Q-D-G-K-L-I-E-V-L-K-S-N-H-H-K-P-G-K-G-N-T-V-M-Q-M-D-L-R-D-V-M-S-G-A-V-V-H-K-T-M-R-P-S-E-K-V-D-L-V-N-V-S-L-K-K-A-Q-Y-L-Y-D-D-D-T-D-F-I-F-M-D-T-D-T-Y-E-Q-Y-L-I-P-K-E-H-L-A-S-E-A-K-F-L-M-P-N-I-E-V-D-L-K-F-T-D-E-G-K-L-I-G-I-N-L-P-S-T-V-K-M-T-V-K-E-T-Q-P-E-I-K-G-A-T-A-A-G-G-G-K-P-A-T-M-D-T-G-L-V-V-T-V-P-D-F-I-K-E-G-E-E-L-I-I-G-T-E-N-G-D-Y-K-G-R-A-D-S-I-T-R"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-G-K-V-E-S-F-E-L-D-H-T-K-V-K-A-P-Y-V-R-L-I-T-V-E-E-G-Q-K-G-D-K-I-S-N-F-D-L-R-L-V-Q-P-N-E-N-A-I-P-T-G-G-L-H-T-I-E-H-L-L-A-G-L-L-R-D-R-I-D-G-Y-I-D-C-S-P-F-G-C-R-T-G-F-H-L-L-V-W-G-T-P-S-T-T-D-V-A-K-A-L-K-E-S-L-E-E-I-R-D-N-I-T-W-E-D-V-P-G-T-T-I-E-S-C-G-N-Y-R-D-H-S-L-F-S-A-K-Q-W-S-R-D-I-L-E-K-G-I-S-D-D-P-F-E-R-H-V-V-E"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-V-K-E-F-K-E-F-I-S-R-G-N-M-M-D-L-A-V-G-V-I-I-G-A-A-F-T-A-I-V-N-S-L-V-K-D-L-I-N-P-L-I-G-L-F-I-G-K-I-D-L-S-N-L-K-F-T-I-G-E-A-T-F-K-Y-G-S-F-L-N-A-V-I-N-F-L-I-I-A-L-V-V-F-F-L-I-K-L-V-N-K-I-T-P-K-K-E-V-E-E-D-P-A-P-T-N-E-E-I-Y-L-R-Q-I-R-D-L-L-Q-E-K-N-K"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-K-I-T-K-D-E-I-N-H-V-A-A-L-S-R-L-E-F-G-E-D-E-I-D-K-F-T-E-Q-M-G-D-I-I-N-M-A-H-Q-L-A-E-V-D-T-E-G-V-P-E-T-V-Q-V-V-D-R-E-T-D-F-R-E-D-K-P-E-H-W-E-S-R-A-E-L-M-K-N-V-P-E-K-A-D-G-F-I-K-V-P-V-I-I-D-K-D-D-N-E"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-E-C-P-N-C-H-K-N-A-S-R-V-I-D-S-R-P-S-D-E-N-R-A-I-R-R-R-R-E-C-E-N-C-G-F-R-F-T-T-F-E-R-V-E-R-S-P-L-L-V-V-K-N-D-G-T-R-E-A-F-N-R-D-K-I-L-H-G-V-M-M-A-A-Q-K-R-P-I-S-S-E-Q-L-D-A-L-V-D-H-V-E-N-E-I-R-K-Q-G-L-N-E-I-S-S-K-D-I-G-N-L-V-M-K-E-L-A-N-L-D-D-V-A-Y-I-R-F-A-S-I-Y-R-Q-F-K-D-V-S-G-F-M-E-A-M-E-D-M-M-A-K-H-D-K-E"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-I-L-N-E-D-I-R-A-R-E-V-R-L-I-G-V-D-G-Q-Q-V-G-V-V-S-K-N-E-A-L-R-K-A-A-D-A-D-L-D-L-V-L-L-S-P-N-A-K-P-P-V-A-R-I-M-D-Y-G-K-F-R-F-E-Q-Q-K-K-A-K-E-N-R-K-N-Q-K-V-M-A-V-K-E-I-R-L-S-P-T-I-E-G-N-D-F-D-T-K-L-K-H-V-R-K-F-L-T-K-G-A-K-V-R-V-S-I-R-F-R-G-R-A-I-T-H-K-E-L-G-K-Q-V-L-E-K-M-A-D-E-A-S-D-L-S-N-V-V-T-K-P-K-M-E-G-R-S-M-F-L-M-L-A-P-L-S-E-K-D-K-K-K-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-T-K-G-G-T-V-T-R-A-R-R-K-K-I-M-K-L-A-K-G-Y-R-G-S-K-H-L-Q-F-K-A-A-S-T-Q-V-F-V-S-R-K-Y-A-F-R-D-R-K-K-R-K-S-E-F-R-K-L-W-I-A-R-I-N-A-A-A-R-Q-N-G-L-S-Y-S-K-L-M-H-G-L-K-V-A-G-I-D-M-N-R-K-M-L-A-D-I-A-Y-N-D-E-K-T-F-A-D-L-A-D-A-A-K-K-A-L-N"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-K-T-G-G-K-Q-Y-K-V-A-K-G-D-S-V-F-V-E-K-L-E-V-K-P-G-D-E-V-T-F-D-E-V-I-L-V-N-D-G-K-S-T-K-I-G-T-P-V-V-E-G-A-K-V-V-A-K-V-E-K-Q-G-K-E-K-K-V-V-T-F-K-Y-K-P-K-K-H-S-H-T-K-Y-G-H-R-Q-P-Y-T-K-V-T-I-E-S-I-E-A"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-T-M-I-S-V-N-E-F-K-N-G-L-T-I-E-Y-N-N-D-L-W-R-I-V-E-F-Q-H-V-K-P-G-K-G-S-A-F-V-R-S-K-L-K-S-L-R-T-G-A-V-Q-E-Y-T-F-R-S-T-A-K-V-N-T-A-D-I-Q-T-K-A-M-Q-Y-L-Y-N-D-G-T-S-F-V-F-M-D-T-N-T-Y-E-Q-L-E-I-P-E-A-Q-V-E-R-E-S-K-F-L-K-E-N-M-V-V-N-V-I-T-H-E-G-E-T-L-G-V-D-L-P-N-T-V-D-L-E-V-A-E-T-E-P-N-I-K-G-D-T-S-S-G-G-G-K-P-A-T-M-E-T-G-L-V-V-N-V-P-F-F-I-N-Q-G-D-V-L-T-I-N-T-A-D-G-T-Y-V-S-R-A-N-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-I-K-K-N-N-F-E-E-Q-L-N-E-L-Q-E-I-V-N-K-L-E-S-G-N-V-P-L-E-D-A-L-S-E-F-Q-A-G-V-K-L-S-R-E-L-E-K-K-L-N-D-A-E-Q-T-V-A-K-L-V-D-K-D-G-N-E-K-A-L-D-P-Q-N-A-S-A-P-E-E-E"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-K-I-T-Y-P-S-I-D-K-L-L-S-R-V-N-S-R-Y-S-L-S-V-L-A-A-K-R-A-H-E-I-Q-A-G-A-P-L-A-L-K-H-Y-K-S-D-K-A-V-G-E-A-L-E-E-I-A-A-G-K-V-T-I-D-P-E-H-R-E-D-I-G"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-T-E-E-E-I-F-N-K-I-A-D-M-I-S-E-R-F-S-I-D-R-D-K-I-T-K-D-L-N-F-Q-N-D-L-D-A-D-S-I-D-F-V-E-L-V-M-D-L-E-D-T-F-G-A-E-I-P-D-D-D-A-E-K-L-Q-T-V-G-E-A-V-E-Y-I-K-S-H-Q-N"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-E-Y-F-E-V-G-K-I-L-S-P-H-G-L-K-G-E-V-K-V-N-A-T-T-D-F-P-E-E-R-L-A-T-G-S-R-L-F-I-K-N-N-K-Q-Y-E-E-L-I-V-E-N-T-R-R-H-K-Q-F-Y-L-V-K-F-E-K-I-D-D-I-D-Q-A-E-K-I-C-S-K-E-L-Y-V-A-E-T-D-Q-Q-E-L-P-E-G-S-Y-Y-F-K-D-I-L-N-C-P-V-Y-D-A-E-T-G-E-K-L-G-V-L-E-N-I-E-T-P-G-A-N-D-I-W-E-I-K-P-E-K-G-K-S-F-W-I-P-N-I-E-S-V-V-K-K-V-D-L-A-N-K-R-I-E-V-T-L-L-E-G-L-R-D-E-N"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-D-P-L-I-Q-E-L-T-K-E-Q-L-R-D-D-M-P-D-F-R-A-G-D-T-V-R-V-H-V-R-V-V-E-G-T-H-E-R-I-Q-M-F-E-G-V-V-I-K-R-K-G-A-G-I-S-A-T-Y-T-V-R-K-M-S-S-G-I-G-V-E-R-T-F-P-V-N-D-P-R-V-A-K-V-E-V-L-R-H-G-R-V-R-R-A-K-L-Y-Y-L-R-E-R-H-G-K-A-A-R-I-A-E-K-R-R-G"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-K-V-T-E-L-V-A-D-V-V-T-P-L-A-E-A-R-G-D-E-L-V-D-V-E-Y-V-K-E-K-K-Q-Y-Y-L-R-I-Y-V-D-R-R-P-G-G-I-D-I-E-E-I-A-N-L-S-E-L-V-S-E-K-L-D-E-L-D-P-D-P-F-P-E-P-Y-I-L-E-L-S-S-P-G-L-E-R-P-I-K-N-E-K-D-W-E-R-A-K-G-S-Y-I-H-V-S-L-Y-Q-K-I-D-G-E-K-T-F-E-G-T-L-K-D-L-N-Q-D-Q-I-V-L-E-V-K-I-K-T-R-R-K-D-I-T-I-P-R-K-V-I-A-S-S-R-F-A-V-E-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-H-R-I-G-R-V-E-G-E-I-L-R-E-L-T-K-I-L-R-K-D-I-R-D-P-R-L-N-D-V-T-I-T-A-V-E-C-T-N-D-L-S-Y-A-T-V-Y-Y-S-M-L-T-D-D-P-A-K-E-K-E-V-A-E-G-L-D-K-A-K-G-M-M-R-H-L-L-G-Q-T-L-T-V-Y-K-V-P-E-L-I-F-K-R-D-T-S-V-A-Y-G-S-K-I-D-K-L-I-N-Q-V-K-K-Q-D-Q-E-R-E-N-K-N-K"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-K-E-E-F-P-H-E-K-D-L-K-D-E-V-T-P-D-K-A-P-K-K-D-P-K-A-A-P-K-E-E-V-K-E-N-P-V-E-N-Y-E-K-E-I-A-E-L-T-A-K-N-K-D-L-E-D-K-Y-L-R-S-E-A-E-I-Q-N-M-Q-A-R-Y-A-K-E-R-A-Q-L-I-K-Y-E-S-Q-S-L-A-K-E-V-L-P-A-M-D-N-L-E-R-A-L-A-V-K-A-D-D-E-A-A-K-Q-L-Q-K-G-V-Q-M-T-L-D-S-L-V-K-S-M-K-D-Q-G-I-T-E-I-K-A-E-G-E-T-F-D-P-S-L-H-Q-A-V-Q-T-V-A-A-E-N-D-E-R-K-D-R-V-V-K-V-L-Q-K-G-Y-Q-Y-K-D-R-T-L-R-P-A-M-V-V-V-A-Q"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-A-I-D-F-K-E-H-I-A-S-V-Q-D-F-P-N-K-G-I-V-F-R-D-I-T-P-I-L-Q-D-G-K-L-Y-R-A-A-T-H-E-L-A-D-Y-A-K-S-R-G-A-E-V-I-V-G-P-E-A-R-G-F-I-V-G-C-P-V-A-T-E-L-G-V-G-F-V-P-A-R-K-P-H-K-L-P-R-E-V-E-S-A-S-Y-D-L-E-Y-G-S-N-V-L-E-M-H-K-D-A-I-K-P-G-Q-K-V-V-I-C-D-D-L-M-A-T-A-G-T-L-H-A-T-K-E-L-I-E-N-L-G-G-E-V-V-G-A-A-F-Y-I-E-L-T-D-L-K-G-R-E-Q-F-P-D-L-D-I-Y-S-L-V-K-Y-S-D-A"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-N-N-L-D-I-S-F-N-D-E-V-N-F-L-K-D-S-D-K-D-W-I-T-W-I-S-N-L-L-L-S-A-K-K-E-I-H-K-E-N-T-Q-E-M-S-I-N-F-V-S-S-K-K-I-H-E-I-N-K-K-Y-R-G-K-D-R-P-T-D-V-I-S-F-A-I-E-D-G-L-D-E-D-F-I-S-A-F-S-D-D-P-D-F-V-E-D-I-G-D-L-F-L-C-P-E-V-I-K-R-H-S-V-E-Y-E-T-G-F-N-R-E-F-G-Y-T-L-V-H-G-Y-L-H-L-N-G-Y-D-H-I-E-D-D-E-A-K-V-M-F-G-I-Q-G-K-V-L-R-E-Y-G-L-P-L-H-P-D-Q-E-N-H-G-K-Q-I-H"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-A-S-K-E-A-E-L-E-A-L-L-Y-A-A-G-D-D-G-L-E-T-E-N-L-L-Q-L-L-E-I-S-P-A-A-L-R-E-L-A-N-H-L-K-D-R-L-K-N-D-E-N-S-G-L-Q-L-I-C-I-N-Q-T-Y-K-L-T-T-S-P-K-C-G-D-I-I-S-K-F-F-Q-K-D-L-S-K-N-L-S-Q-S-A-L-E-I-L-S-I-I-A-Y-R-Q-P-I-T-R-V-E-I-D-D-L-R-G-V-N-S-A-G-A-L-Q-T-L-V-W-R-G-L-I-K-V-D-G-K-K-D-V-P-G-H-P-N-L-Y-V-T-T-D-Y-F-L-Q-Y-F-N-Y-E-S-L-A-D-L-P-V-I-E-E-F-E-A-D-D-N-P-V-N-L-F-N-Q-D-D-S-R-N-K-E-I-N-F-D-E-G-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-D-E-L-I-K-E-Y-A-R-H-D-G-D-T-G-S-P-E-V-Q-I-A-L-L-T-S-D-I-N-N-L-N-D-H-L-K-A-N-K-Q-D-H-H-S-Y-V-G-L-L-K-K-I-G-H-R-R-N-L-L-R-Y-L-K-N-K-D-I-Q-R-Y-R-E-L-I-N-K-L-G-L-R-R"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-Q-I-K-S-A-I-K-R-V-K-T-N-A-T-A-N-K-R-N-A-A-E-L-S-K-L-R-T-A-V-R-K-F-N-E-A-V-E-N-D-A-K-D-V-L-D-L-E-V-K-A-A-R-A-L-D-K-A-A-S-K-G-L-I-S-K-N-K-A-N-R-D-K-S-R-L-S-K-K-A-A-N-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-L-M-H-D-I-T-R-D-G-N-P-V-L-R-Q-V-A-K-P-L-T-F-P-L-S-D-E-Y-K-K-L-A-D-D-M-M-Q-Y-L-I-N-S-Q-D-P-K-I-A-E-K-H-Q-L-R-A-G-V-G-L-A-A-P-Q-V-G-E-S-V-Q-M-A-A-L-L-V-P-N-D-K-G-E-I-I-F-K-E-V-F-V-N-P-K-I-L-S-E-S-V-R-R-T-C-L-A-E-G-E-G-C-L-S-V-D-K-D-I-E-G-Y-V-P-R-P-D-K-L-K-I-R-Y-Y-T-V-D-G-E-E-K-T-I-R-L-K-D-Y-P-A-I-V-A-S-H-E-I-D-H-L-N-G-H-L-F-Y-D-R-I-N-K-Q-N-P-F-E-L-A-E-D-T-I-V-I-S"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-L-Y-Q-K-D-Q-I-V-N-P-R-R-E-T-T-K-T-L-F-L-E-A-D-N-V-V-A-A-R-T-M-V-E-D-N-T-P-Y-N-I-E-L-I-Q-E-L-T-G-N-S-L-A-Y-E-K-Q-S-P-D-F-K-L-T-T-F-D-S-K-D-N"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-F-D-K-L-G-R-F-F-G-I-S-E-D-D-E-M-N-E-V-P-Y-T-E-S-E-E-Q-Q-E-E-I-P-Q-T-Q-K-N-E-R-R-A-N-V-V-S-I-N-S-G-V-S-A-T-S-K-I-V-L-Y-E-P-R-V-Y-S-D-A-K-E-V-A-Q-N-L-L-N-N-K-A-V-I-I-N-F-A-R-M-D-D-E-Q-A-R-R-I-V-D-F-I-T-G-T-V-Y-A-L-N-G-E-I-Q-R-V-G-D-K-I-F-L-A-T-P-P-K-F-E-T-D-G-K-I-A-E-L-V-E-K-K-D-K-M-D"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-D-P-E-K-I-I-K-V-S-V-V-T-P-D-G-I-V-Y-S-H-N-A-T-M-V-A-M-R-A-I-D-G-D-R-A-I-M-Y-D-H-L-P-I-V-T-P-L-A-I-G-E-V-R-V-K-R-T-H-E-M-N-D-R-I-D-H-I-A-V-N-G-G-Y-I-E-F-S-N-N-E-A-T-I-I-A-D-S-A-E-R-A-R-N-I-D-V-K-R-A-Q-S-A-K-K-R-A-E-Q-H-M-Q-E-A-K-E-K-H-N-E-R-E-M-L-E-A-E-I-A-L-R-R-A-V-N-R-L-H-V-R-E-N-Y-G-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-L-S-R-E-E-I-A-S-R-Y-S-K-A-L-F-A-Y-A-Q-D-A-N-S-L-D-A-V-H-E-D-M-N-V-L-L-Q-V-A-K-E-N-P-D-M-L-R-L-L-S-D-P-I-I-R-K-N-Q-K-E-E-F-L-S-S-F-S-D-K-F-S-S-E-T-K-N-F-L-D-F-L-L-E-Y-R-R-F-E-S-L-T-A-I-I-E-A-F-N-T-L-Y-D-E-Y-K-N-I-A-S-G-T-A-V-S-A-I-K-L-N-E-D-E-L-S-R-I-S-Q-A-Y-A-K-K-Y-G-F-K-E-L-I-L-T-N-K-V-D-P-S-I-L-G-G-I-I-L-K-V-G-D-R-I-I-D-G-S-I-R-T-R-L-Q-Q-I-R-E-Q-L-I-E-N-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-Q-F-M-F-A-A-L-K-L-E-L-G-D-T-L-Y-Y-L-L-I-F-A-A-L-L-L-L-V-K-H-F-A-W-G-P-V-T-K-M-M-E-E-R-R-Q-K-V-I-S-D-L-D-Q-A-E-S-D-R-K-K-A-E-L-L-A-N-Q-R-E-A-A-L-K-D-S-K-Q-E-A-T-Q-I-L-S-T-A-K-S-N-A-E-K-T-K-N-N-I-I-S-Q-A-D-Q-E-A-A-A-I-R-K-R-A-S-E-D-A-A-Q-A-K-T-D-A-L-N-E-A-R-D-Q-V-A-D-I-S-V-A-I-A-E-K-V-I-S-K-N-L-S-A-A-D-Q-K-D-L-V-D-Q-F-I-K-G-L-N-D"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-Q-K-A-D-N-L-I-A-Q-N-K-K-A-S-H-D-Y-F-I-K-E-T-L-E-A-G-I-A-L-T-G-T-E-I-K-S-I-R-A-R-R-I-N-L-R-D-G-Y-V-Q-I-I-N-G-S-A-F-L-E-N-V-H-I-S-E-Y-K-E-G-N-R-Y-N-H-D-P-L-R-S-R-R-L-L-L-H-K-R-E-I-A-R-L-A-G-I-Q-A-Q-Q-G-M-A-I-I-P-L-K-V-Y-L-K-H-G-F-A-K-V-L-I-G-V-G-Q-G-K-K-Q-Y-D-K-R-Q-T-I-K-K-R-D-Q-D-R-E-I-H-R-K-Y-G-I"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-L-V-P-T-V-I-E-Q-T-A-R-G-E-R-A-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-S-G-E-I-N-D-Q-M-A-N-S-I-I-A-Q-L-L-F-L-D-A-Q-D-N-T-K-D-I-S-L-Y-I-N-S-P-G-G-V-I-T-S-G-L-A-I-M-D-T-M-N-F-I-K-S-D-V-S-T-I-A-I-G-M-A-A-S-M-A-S-I-L-L-T-S-G-T-K-G-K-R-F-A-L-P-N-S-T-V-L-I-H-Q-P-L-G-G-A-Q-G-Q-Q-T-D-I-Q-I-A-A-N-E-I-L-K-S-R-K-K-L-N-Q-I-L-H-E-T-T-G-Q-P-L-D-K-I-L-K-D-T-E-R-D-N-Y-L-S-A-E-E-A-K-D-Y-G-L-I-D-E-I-L-V-N-Q-K-K-D"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-L-L-G-L-D-V-G-S-K-T-V-G-V-A-I-S-D-P-L-G-I-T-A-Q-E-L-E-T-I-K-I-D-E-S-K-F-S-F-G-L-R-Q-I-R-R-I-V-R-K-Y-D-V-E-G-F-V-L-G-L-P-K-N-M-D-G-S-S-G-H-S-V-E-R-S-K-Q-Y-G-E-R-L-K-E-K-F-D-L-P-V-Y-Y-M-D-E-R-L-T-T-V-Q-A-D-R-I-L-V-E-E-A-G-V-H-D-R-V-E-R-K-K-V-I-D-Q-M-A-A-V-L-I-L-Q-N-Y-L-E-A-T-R-K-D-N"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-F-E-Y-L-K-G-I-V-T-K-I-D-P-A-Y-I-V-L-D-V-N-G-V-G-Y-K-I-L-C-P-T-P-Y-S-Y-D-E-N-Q-P-A-T-I-Y-V-E-Q-V-V-R-D-T-G-I-T-L-Y-G-F-L-S-L-E-D-K-E-L-F-L-K-L-L-S-V-S-G-I-G-P-K-S-A-V-A-I-M-A-A-E-D-T-D-S-L-A-S-A-I-Q-N-G-E-V-K-Y-L-T-R-F-P-G-V-G-K-K-T-A-S-Q-I-V-L-D-L-K-G-K-L-G-D-Y-V-K-K-S-T-A-A-A-D-L-T-P-S-L-Q-D-A-L-L-A-L-V-A-L-G-Y-T-Q-K-E-V-D-R-I-T-P-K-L-A-K-L-P-E-N-T-A-D-G-Y-V-K-E-A-L-A-L-L-L-K-K"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Q-Y-P-L-P-I-A-R-L-I-D-N-Y-M-K-L-P-G-I-G-E-K-T-A-T-R-L-A-F-Y-T-M-D-M-P-E-Q-D-V-E-D-F-S-K-S-L-M-Q-V-K-E-N-L-H-S-C-S-I-C-G-N-I-T-E-S-D-P-C-E-I-C-R-D-S-N-R-D-R-S-T-I-M-V-V-E-Q-P-K-D-V-M-A-F-E-E-M-G-E-Y-N-G-L-Y-H-V-L-H-G-V-L-S-P-M-D-G-V-G-P-E-E-I-N-I-K-S-L-I-T-R-L-Q-K-Q-D-E-V-K-E-V-I-L-A-L-N-S-S-P-E-G-E-A-T-A-M-Y-L-A-K-L-I-K-P-A-G-L-K-V-T-R-L-A-A-G-L-A-V-G-S-D-I-E-Y-A-N-S-I-T-L-K-R-A-V-Q-G-R-T-D-L"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-G-K-R-P-N-F-G-G-M-G-M-G-N-M-Q-G-L-I-K-Q-A-K-K-M-Q-Q-Q-M-E-A-E-Q-A-N-L-A-T-Q-E-F-V-G-K-A-A-D-D-M-V-V-A-T-F-S-G-D-R-K-L-K-D-L-K-I-N-K-E-A-I-D-P-D-D-P-D-M-L-Q-D-L-V-I-D-A-V-N-K-G-I-K-A-V-D-D-A-T-Q-A-S-M-G-K-Y-T-K-G-L-M"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-D-T-E-K-I-I-E-D-L-K-G-A-S-I-L-E-L-N-D-L-V-K-A-I-E-D-E-F-G-V-S-A-A-A-P-V-A-A-A-G-A-A-G-A-G-A-E-K-T-E-F-D-V-E-L-T-D-V-G-Q-E-K-V-K-V-I-K-V-V-R-D-I-T-G-L-G-L-K-D-S-K-D-L-V-D-G-A-P-K-N-V-K-E-G-V-S-E-D-E-A-N-D-I-K-A-K-L-E-E-V-G-A-T-V-T-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-K-A-I-I-A-K-K-E-K-L-V-D-D-F-A-A-E-L-K-E-A-K-A-I-L-V-I-D-Y-L-G-L-T-V-E-E-V-T-N-L-R-K-D-L-R-D-A-N-V-K-M-K-V-I-K-N-T-Y-L-K-R-A-A-E-K-A-G-I-E-G-L-E-D-T-F-V-G-P-T-A-V-V-Y-T-A-D-A-E-D-I-T-E-P-A-R-I-V-S-K-Y-E-D-D-I-D-A-L-S-I-K-G-G-M-L-E-G-K-V-A-S-Q-E-E-I-K-K-L-A-A-I-P-G-R-E-G-L-L-S-M-L-V-S-V-L-Q-A-P-V-R-N-F-A-Y-A-V-K-A-V-A-D-S-K-D-E"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-P-L-A-K-T-S-D-I-K-R-K-W-Y-V-I-D-A-T-D-V-S-L-G-R-L-S-T-A-V-A-S-I-L-R-G-K-N-K-P-Q-Y-T-P-N-V-D-T-G-D-Y-V-I-V-V-N-A-A-K-L-K-L-T-G-K-K-A-T-D-K-I-Y-Y-R-H-S-D-Y-R-G-G-L-R-A-T-P-A-G-E-L-L-A-K-N-P-V-R-L-V-E-L-S-V-K-G-M-L-P-K-N-T-L-G-H-Q-E-F-M-K-M-H-V-Y-A-G-E-D-H-E-H-A-A-Q-K-P-E-K-L-D-I-N-E-L-I"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-A-K-K-T-A-R-K-R-R-V-K-K-H-V-E-S-G-V-A-H-I-H-S-T-F-N-N-T-L-V-M-I-T-D-V-Q-G-N-A-V-A-W-S-S-A-G-A-L-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-A-A-A-K-S-A-M-D-Q-G-M-K-H-V-E-V-S-V-K-G-P-G-A-G-R-E-A-A-I-R-A-L-Q-A-A-G-L-E-I-T-A-I-R-D-V-T-P-V-P-H-N-G-S-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-L-P-R-N-K-R-V-V-V-A-L-T-Y-I-Y-G-I-G-E-P-T-A-K-K-I-C-K-D-A-G-I-S-E-D-I-R-T-N-D-L-T-P-E-D-Q-E-K-L-R-S-E-V-D-K-Y-R-V-E-G-D-L-R-R-E-V-S-L-N-I-K-R-L-V-E-I-G-S-Y-R-G-I-R-H-R-R-G-L-P-V-R-G-Q-N-T-K-N-N-A-R-T-R-K-G-S-K-R-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-E-L-K-P-N-E-G-S-R-R-N-R-K-R-V-G-R-G-T-S-S-G-Y-G-K-T-A-G-R-G-Q-K-G-Q-L-A-R-T-G-G-K-T-R-L-G-F-E-G-G-Q-M-P-L-F-R-R-M-P-K-R-G-F-K-N-V-N-R-K-E-Y-A-I-I-N-L-N-D-L-N-R-F-D-D-G-S-E-V-T-I-D-T-L-K-S-S-G-L-V-K-K-E-L-A-G-V-K-L-L-A-N-G-E-L-K-V-K-L-T-V-K-V-N-K-A-S-E-A-A-K-K-A-V-E-A-A-G-G-T-V-E-V-I"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-N-R-N-D-S-R-R-D-S-R-K-D-R-K-K-D-D-I-E-D-Q-L-V-A-I-N-R-I-T-K-V-V-K-G-G-R-R-M-R-F-A-A-V-V-I-V-G-D-R-K-G-H-V-G-F-G-T-G-K-A-Q-E-V-P-E-A-I-R-K-A-V-E-A-G-K-K-R-M-I-K-V-P-T-V-G-T-T-I-P-H-E-V-M-G-H-Y-G-S-G-N-I-M-L-K-P-A-E-A-G-S-G-V-A-A-G-G-A-V-R-I-I-M-D-L-A-G-I-S-D-V-T-S-K-S-L-G-S-N-T-P-I-N-V-I-R-A-T-M-D-G-L-S-K-L-K-T-R-E-D-V-L-K-L-R-E-S-A-K-S-L-E-D"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-L-R-L-K-R-H-K-R-I-R-G-K-I-S-G-T-A-E-R-P-R-L-S-V-F-R-S-N-K-N-I-Y-A-Q-L-I-D-D-V-E-G-V-T-L-A-S-A-S-T-N-D-K-N-I-S-A-E-G-S-K-M-E-Q-A-A-E-V-G-K-A-L-A-E-T-A-A-K-K-N-I-K-S-V-V-F-D-R-S-G-Y-L-Y-H-G-R-I-Q-A-L-A-D-A-A-R-E-N-G-L-E-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-L-K-V-I-E-V-P-E-K-V-T-V-T-K-N-G-D-D-I-T-V-K-G-P-K-G-E-L-T-R-Y-F-D-P-R-I-T-F-E-Q-K-D-G-E-I-H-F-S-R-S-S-E-A-D-K-A-L-H-G-T-E-R-A-N-L-A-S-M-I-E-G-V-T-D-G-Y-V-K-K-L-T-L-V-G-V-G-Y-R-A-V-A-Q-G-K-K-L-T-L-N-V-G-Y-S-H-P-V-E-F-E-A-P-E-G-I-T-V-K-T-P-S-A-T-S-I-E-I-E-G-I-S-K-Q-V-V-G-Q-F-A-A-E-I-R-D-V-R-P-P-E-P-Y-K-G-K-G-I-R-Y-E-D-E-Y-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-Y-L-T-R-I-R-N-A-N-M-A-K-H-T-S-V-E-I-P-A-S-S-M-K-K-S-L-S-E-I-L-K-N-E-G-F-I-R-D-Y-Q-V-E-D-D-N-K-Q-G-M-I-K-I-F-L-K-Y-G-P-N-N-E-R-V-I-S-G-L-K-R-I-S-K-P-G-L-R-N-Y-V-S-A-E-N-L-P-K-V-L-N-G-L-G-I-A-I-I-S-T-S-A-G-V-I-T-D-K-E-A-R-E-K-N-V-G-G-E-V-I-A-Y-V-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-N-S-L-V-E-K-Y-S-N-E-I-A-P-A-M-N-K-K-F-N-Y-D-S-V-M-E-I-P-K-I-D-K-I-V-L-N-M-G-V-G-D-A-V-S-N-A-K-N-L-D-E-A-V-E-E-L-T-L-I-S-G-Q-K-P-L-I-T-K-A-K-K-S-I-A-N-F-R-L-R-E-G-M-S-I-G-A-K-V-T-L-R-G-D-R-M-Y-D-F-L-Y-K-L-I-N-V-S-L-P-R-V-R-D-F-R-G-I-S-S-R-S-F-D-G-R-G-N-Y-T-L-G-I-K-E-Q-L-I-F-P-E-I-D-Y-D-K-V-N-R-V-R-G-L-D-V-V-I-V-T-T-A-K-T-D-E-E-A-R-E-L-L-T-E-F-G-M-P-F-A-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-H-E-S-R-L-K-V-A-D-N-S-G-A-R-E-L-L-V-I-K-I-L-G-G-S-K-R-K-T-G-N-I-G-D-I-V-V-A-A-V-K-Q-A-T-P-G-G-V-V-K-K-G-D-V-V-K-A-V-I-V-R-T-K-S-G-A-R-R-E-D-G-S-Y-I-K-F-D-E-N-A-A-V-V-I-N-A-D-K-S-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-H-D-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-T-N-E-R-N-N-R-H-V-Y-Q-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-D-T-Y-K-N-H-P-V-Y-K-K-R-I-K-Y-S-K-K-Y-Y-A-H-D-E-N-N-E-A-K-I-G-D-T-V-R-I-M-E-T-R-P-L-S-H-A-K-R-Y-R-L-T-K-I-V-K-K-S-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-H-R-R-E-F-R-G-K-M-R-G-E-A-K-G-G-K-T-I-A-F-G-E-Y-G-L-E-A-V-E-S-H-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-F-M-K-R-G-G-K-V-W-I-R-I-F-P-Q-K-S-Y-T-A-K-G-V-G-V-R-M-G-S-G-K-G-A-P-A-G-W-V-A-V-V-K-R-G-K-I-M-F-E-I-G-G-V-S-E-D-V-A-R-E-A-L-R-L-A-S-N-K-L-P-I-K-T-K-F-V-K-K-S-S-E-V-G-G-E-S-N-E-G"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-E-Q-I-S-S-A-K-A-E-A-R-T-V-R-I-A-P-R-K-A-R-L-V-V-D-L-I-R-G-K-S-V-A-E-A-L-A-I-L-Q-F-T-P-R-A-A-S-P-I-V-E-K-V-L-K-S-A-I-A-N-A-E-H-N-Y-D-L-E-S-A-N-L-Y-V-S-E-A-Y-V-N-E-G-A-T-L-K-R-F-R-P-R-A-K-G-M-A-S-P-I-N-K-R-T-S-H-V-V-V-V-V-S-E-K-N-D"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-I-K-K-G-P-F-A-D-A-S-L-L-K-K-I-E-A-Q-E-G-S-E-K-K-Q-V-I-K-T-W-S-R-R-S-T-I-F-P-S-F-V-G-F-T-I-A-V-Y-D-G-R-K-H-V-P-V-Y-I-T-E-D-M-V-G-H-K-L-G-E-F-V-P-T-R-T-F-R-G-H-K-V-A-D-K-A-T-T-T-V-G-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-D-A-R-D-I-I-L-R-P-V-V-T-E-K-S-M-N-L-M-D-D-K-K-Y-T-F-D-V-L-V-S-A-T-K-T-Q-V-R-N-A-I-E-E-I-F-D-V-K-V-K-N-V-N-I-M-N-V-R-G-K-E-K-R-V-G-R-Y-T-G-K-T-A-R-R-R-K-A-I-V-T-L-T-E-D-S-N-D-I-K-I-F-N-D-N-K-E-N"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-S-Q-Q-I-R-I-R-L-K-S-Y-E-H-G-I-L-D-E-S-A-A-K-I-V-A-T-A-E-R-T-G-A-Q-I-S-G-P-V-P-L-P-T-E-R-T-L-F-T-V-L-R-S-P-H-K-N-K-D-S-R-E-Q-F-E-I-R-T-H-K-R-L-I-D-I-L-N-P-T-P-K-T-V-D-S-L-M-K-L-D-L-P-S-G-V-D-I-E-I-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-N-I-A-K-R-D-V-L-A-D-P-V-Y-N-S-K-L-V-T-K-L-I-N-H-L-M-I-D-G-K-K-A-K-A-S-S-I-L-Y-D-A-F-G-I-I-Q-D-K-T-G-K-E-P-V-E-V-F-E-E-A-M-N-N-V-M-P-V-L-E-V-K-A-R-R-I-G-G-S-N-Y-Q-I-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-S-Y-A-R-L-R-N-E-H-T-M-D-E-R-L-A-N-E-I-M-D-A-A-N-N-T-G-S-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-R-A-F-A-H-Y-R-F"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-K-G-R-H-S-K-T-T-K-S-D-S-P-A-L-N-Y-A-Y-N-S-M-K-K-K-M-N-Y-N-P-A-P-Q-M-R-G-V-A-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-Y-A-R-V-R-L-S-N-L-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-I-R-G-A-L-D-T-A-G-V-D-G-R-K-Q-G-R-S-K-Y-G-A-K-K-G"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-T-G-L-G-N-P-G-R-K-Y-D-Q-T-K-H-N-T-G-F-M-A-L-D-H-Y-L-E-K-N-G-L-T-L-D-K-N-K-F-E-G-L-W-T-K-Q-K-I-N-G-E-D-V-I-F-L-E-P-Q-T-F-M-N-D-S-G-K-S-I-A-Q-V-A-N-F-F-K-I-K-P-E-D-I-L-V-I-H-D-D-M-D-M-P-I-G-K-I-R-I-R-A-N-G-K-S-G-G-H-N-G-I-K-S-I-M-A-C-L-G-T-N-N-F-N-R-L-K-I-G-I-R-H-P-E-N-E-S-V-V-S-W-V-L-S-P-F-N-N-D-Q-Q-K-L-M-D-A-A-F-E-T-S-E-N-V-I-N-D-F-I-K-G-K-N-A-Q-Y-L-M-N-Q-Y-N"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-R-G-V-G-I-D-S-V-E-V-E-R-M-K-K-I-V-E-K-G-D-K-F-A-K-R-V-L-T-P-K-E-F-E-Q-Y-Q-Q-L-K-G-K-R-K-V-E-Y-L-G-G-R-F-S-L-K-E-S-F-S-K-A-M-G-T-G-L-G-K-Y-V-G-F-Q-D-I-E-T-L-W-D-D-L-G-H-P-V-M-T-S-T-K-F-S-G-N-I-F-P-S-I-T-H-D-D-H-E-I-I-T-V-V-V-L-E-E-L-N"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-G-L-D-D-F-Q-G-Q-N-K-D-E-L-S-M-I-E-V-A-R-A-I-L-Q-D-S-G-K-R-M-A-F-A-D-I-V-N-A-V-Q-N-F-L-G-K-S-D-E-E-I-R-E-R-L-P-Q-F-Y-T-D-M-N-T-D-G-E-F-I-S-M-G-H-N-V-W-A-L-R-S-W-F-P-Y-E-S-V-D-E-E-V-N-H-P-E-D-E-E-D-V-P-R-K-K-H-H-K-K-V-N-A-F-I-G-D-S-D-D-D-D-I-I-D-Y-D-S-D-D-P-E-D-E-D-L-D-V-D-E-E-D-T-N-E-D-D-Y-S-D-D-D-L-D-D-A-D-D-N-E-L-D-D-G-I-E-G-Q-L-S-E-L-H-Q-D-D-L-D-D-D-D-E"} +{"text": "### FUNCTION Catalyzes the cleavage of the glycosidic bond of 2'-deoxyribonucleosides and the transfer of the deoxyribosyl moiety to an acceptor purine or pyrimidine base ### SEQUENCE -M-A-G-W-F-T-E-T-Q-N-K-A-Y-K-D-A-M-S-A-L-N-A-N-P-T-I-D-L-E-N-S-Y-V-P-L-Q-N-Q-Y-K-D-I-R-V-D-E-H-P-E-Y-L-H-D-K-E-W-A-Q-A-T-Y-N-G-D-L-V-G-I-K-T-S-D-V-M-L-G-V-Y-V-P-K-E-E-D-V-G-L-G-M-E-L-G-Y-A-M-S-Q-G-K-Y-V-L-L-V-I-P-D-E-L-Y-G-E-S-I-N-L-M-S-W-G-V-A-D-N-V-I-K-M-S-E-L-A-T-F-D-F-N-R-P-R-Y-N-F-Y-D-G-A-V-Y"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-N-I-K-I-V-C-V-G-K-L-K-E-K-Y-F-K-D-G-I-A-E-Y-V-K-R-M-S-R-F-A-K-V-K-I-V-Q-V-P-D-E-K-A-P-E-K-L-S-P-A-E-M-E-Q-V-K-E-I-E-G-K-R-I-L-D-K-I-K-D-K-E-Y-V-Y-V-T-A-I-K-G-K-E-R-T-S-E-A-F-A-K-E-L-S-D-L-T-T-Y-G-H-S-D-I-T-F-V-I-G-G-S-L-G-T-S-D-A-V-N-K-R-A-D-D-L-I-S-F-G-K-F-T-M-P-H-Q-L-M-R-L-V-L-I-E-Q-I-Y-R-A-F-M-I-N-S-G-S-P-Y-H-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-I-K-D-M-K-G-K-G-K-R-G-E-V-K-N-V-P-D-G-Y-A-Q-N-F-L-I-K-N-G-Y-A-K-E-A-T-S-S-N-L-N-T-L-K-R-V-Q-K-A-E-K-D-A-Y-E-A-E-K-A-A-A-E-D-I-K-K-K-L-E-D-D-K-T-I-V-N-F-K-S-K-A-G-T-D-S-R-L-F-G-S-I-S-S-K-K-I-V-E-G-L-E-K-Q-Y-G-I-K-V-D-K-R-K-L-E-L-P-E-P-I-K-S-L-G-Y-T-N-V-P-V-K-L-F-K-G-V-E-A-V-I-R-V-H-I-T-E-Q-D"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Q-Q-R-R-G-G-R-R-R-R-K-V-D-F-I-A-A-N-H-I-D-Y-I-D-Y-K-D-V-D-L-L-K-R-F-I-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-N-Q-R-K-L-T-V-A-I-K-R-A-R-V-M-G-L-L-P-F-V-A-E-D"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-K-T-K-Y-E-V-T-Y-I-I-K-P-D-I-D-E-D-S-K-K-A-L-I-D-R-F-D-K-V-V-T-D-N-G-A-E-E-L-E-S-K-D-W-G-K-R-R-F-A-Y-E-I-E-K-Y-R-E-G-T-Y-H-I-M-T-F-V-A-E-N-S-E-P-V-D-E-F-G-R-L-S-R-I-D-N-Q-I-L-R-S-M-T-V-K-L-D-K"} +{"text": "### FUNCTION Probable zinc metalloprotease whose natural substrate is unknown ### SEQUENCE -M-L-L-Y-L-V-N-F-Q-S-M-W-A-N-Y-V-L-E-L-L-K-D-A-F-A-F-K-I-K-A-K-E-L-D-I-P-L-A-A-Y-N-P-F-R-K-Q-F-S-A-Q-L-L-L-D-Y-V-V-E-R-Y-K-D-G-L-V-F-A-I-I-D-E-D-I-Y-D-S-N-Y-N-F-V-F-G-L-A-Y-P-F-R-G-A-I-V-S-T-Y-R-L-K-N-F-E-R-I-K-K-E-V-L-H-E-M-G-H-V-F-G-L-G-H-C-N-N-Y-C-V-M-R-F-S-N-S-V-F-E-V-D-E-K-P-D-K-Y-C-E-N-C-Y-R-E-I-L-N-N-G-F-Y-V-N-P-K-Y-V-I-F-K-E-N-Y-N"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-K-K-P-Y-G-E-V-T-K-D-I-V-H-I-A-D-V-D-L-D-G-H-K-P-I-Y-V-E-L-R-K-V-V-G-V-N-W-M-F-A-H-A-V-C-A-A-L-G-I-D-K-W-R-K-I-G-S-L-S-D-E-E-L-E-K-L-E-D-A-L-R-N-P-W-K-Y-G-I-P-S-W-L-Y-N-R-R-R-D-P-E-T-G-K-D-L-H-L-V-G-N-D-Y-K-I-T-M-E-F-D-I-K-R-E-M-Q-I-N-S-W-R-G-Y-R-H-R-E-G-L-P-V-R-G-Q-R-T-R-S-H-H-R-K-G-R-T-V-G-V-I-K-K-K"} +{"text": "### FUNCTION eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA ### SEQUENCE -M-E-Y-N-Y-F-E-L-L-E-R-A-Y-Q-K-L-K-D-V-I-K-Q-E-Q-I-R-W-N-P-P-I-P-H-I-E-Y-V-K-N-R-T-I-I-T-N-F-K-Q-I-A-N-Y-L-N-R-D-P-K-I-I-A-K-F-F-S-K-E-L-F-V-Q-T-I-I-E-G-N-S-L-I-I-N-K-R-V-S-Y-E-T-I-K-K-K-L-D-E-F-I-N-I-F-V-I-C-P-V-C-K-R-P-D-T-E-L-I-E-R-G-R-K-I-Y-Y-I-K-C-H-A-C-G-S-E-S-P-V-N-Y-E-L"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-V-P-N-G-L-F-A-G-R-K-L-K-K-I-R-K-K-F-R-W-N-D-Y-R-Y-V-R-R-M-L-R-I-K-E-K-Y-D-P-L-E-G-A-P-M-A-S-G-I-V-L-E-K-T-D-V-E-R-R-Q-P-N-S-G-R-I-K-V-V-R-V-Q-L-K-K-N-G-K-V-V-T-A-F-T-P-G-D-G-A-I-K-V-I-D-E-H-D-E-V-L-I-V-G-I-R-G-R-Q-G-R-S-M-G-D-I-P-G-V-R-Y-K-V-Y-L-V-N-G-Q-P-L-E-L-L-R-K-G-K-I-E-K-A-R-R"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-P-F-L-R-I-K-I-Y-S-T-D-L-E-E-L-N-R-V-V-E-K-I-K-E-I-V-K-Q-T-G-V-K-M-R-G-P-I-P-L-P-T-K-I-L-R-V-P-V-L-R-I-T-G-H-R-G-T-K-I-W-D-T-Y-Q-M-R-I-H-R-R-I-I-D-I-A-T-D-D-R-T-I-K-L-L-M-R-T-P-L-I-T-K-P-E-K-I-Q-I-Q-L-K-Y-I-K-D-K-N-L"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-H-G-P-R-Y-R-V-P-F-R-R-R-R-E-G-K-T-V-Y-R-K-R-L-K-L-L-L-S-G-K-P-R-L-V-V-R-R-F-N-S-N-I-L-A-Q-L-V-E-Y-D-P-K-G-D-R-V-I-F-T-I-H-S-N-V-L-K-K-Y-G-W-K-G-H-R-G-N-L-P-S-A-Y-L-V-G-L-I-A-G-Y-E-A-L-K-R-G-Y-K-E-A-V-L-D-I-G-R-Y-K-S-T-K-G-N-A-L-Y-A-V-L-K-G-A-L-D-A-G-L-N-I-P-H-S-E-T-I-L-P-S-E-D-R-I-R-G-E-H-I-A-N-Y-A-K-M-L-K-E-N-E-E-L-Y-K-K-Q-F-S-R-Y-L-K-E-G-L-D-P-E-Q-L-P-N-H-F-E-E-V-K-Q-K-I-I-S-Q-Y-Q"} +{"text": "### FUNCTION Endonuclease that removes tRNA introns Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp ### SEQUENCE -M-I-G-Y-L-F-G-N-R-V-L-V-D-D-K-E-L-P-L-I-E-A-Y-Y-L-L-D-K-G-E-L-E-V-Y-E-D-D-K-K-L-S-K-E-E-F-L-K-K-C-L-T-Y-D-E-R-F-L-I-R-Y-K-A-Y-K-E-L-R-D-K-G-Y-T-L-G-T-A-L-K-F-G-A-D-F-R-V-Y-D-I-G-V-I-P-K-K-G-K-R-S-E-R-E-H-S-K-W-V-L-Y-P-V-S-K-D-E-T-F-D-F-Y-E-F-A-S-K-N-R-V-A-H-S-T-R-K-K-L-L-L-G-I-V-S-D-K-I-E-F-I-E-V-S-W-K-K-P"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center ### SEQUENCE -M-K-M-K-L-F-G-R-W-D-Y-E-D-V-T-V-E-D-P-G-L-R-D-Y-I-N-L-K-P-M-L-I-P-Y-S-G-G-R-H-Q-K-H-R-F-G-K-A-K-I-P-I-I-E-R-L-A-G-R-L-M-T-S-G-H-L-G-K-K-H-K-W-T-S-E-H-Q-T-G-K-K-Y-N-A-Y-K-I-I-I-R-T-F-E-I-I-E-K-R-T-K-Q-N-P-L-K-V-F-V-K-A-I-E-N-A-A-P-R-E-E-T-T-T-I-E-Y-G-G-A-R-Y-P-K-A-V-D-C-S-P-Q-R-R-V-D-L-A-I-R-H-M-V-W-G-A-F-H-G-S-R-K-K-P-I-S-I-E-E-A-L-A-E-E-I-I-N-A-Y-N-N-S-L-K-S-Y-A-I-K-R-K-L-E-I-E-K-T-A-E-S-A-R"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-R-I-P-I-I-K-Y-E-I-P-I-P-E-N-V-K-V-S-Y-E-N-N-I-L-K-V-S-G-P-K-G-E-V-E-R-K-F-Y-H-P-L-I-K-L-S-V-N-D-N-K-I-I-L-E-T-Y-F-A-T-R-R-E-K-R-L-I-N-T-W-R-S-H-I-K-N-M-L-E-G-V-Q-N-P-F-V-Y-R-L-K-V-C-Y-T-H-F-P-M-R-V-K-L-E-G-N-K-L-I-V-E-N-F-L-G-E-K-A-P-I-I-K-E-L-P-Y-L-D-K-V-K-V-K-I-E-Q-N-K-D-E-T-E-I-V-V-E-S-P-D-K-E-K-A-G-I-V-A-S-M-I-E-Q-S-T-R-F-L-H-K-R-K-D-R-R-R-F-T-D-G-I-W-L-Y-Y-K-A-G-K-N-I-L-E-E"} +{"text": "### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate forming two phosphate ions ### SEQUENCE -M-E-V-Y-A-F-I-E-V-P-K-G-S-N-V-K-Y-E-Y-E-D-G-K-L-K-V-D-R-I-L-Y-G-A-M-F-Y-P-Y-N-Y-G-F-I-P-E-T-L-E-E-D-G-D-P-L-D-V-L-V-I-T-E-E-P-L-V-P-G-S-Y-I-K-V-K-P-I-G-V-L-V-T-E-D-E-K-G-V-D-R-K-I-I-A-V-P-V-K-K-V-D-P-I-Y-G-E-I-E-D-I-S-E-L-K-E-G-I-K-L-K-I-K-H-F-F-E-R-Y-K-E-L-E-P-G-K-F-V-K-V-K-E-F-L-G-K-E-E-A-E-K-I-I-K-Q-A-Q-E-N-Y-K-K-Q"} +{"text": "### FUNCTION Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein and RNA polymerase recruitment Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes ### SEQUENCE -M-P-T-S-K-Q-I-I-N-K-K-Q-D-E-V-S-D-I-Y-G-K-E-M-I-R-V-I-R-S-L-L-K-H-K-I-I-D-T-E-S-L-S-K-K-T-G-Y-S-I-N-T-V-R-R-A-L-Y-T-L-Q-K-M-G-I-V-R-Y-I-N-K-E-D-K-T-L-W-Q-L-L-E-T-D-Y-E-K-I-L-D-T-L-L-E-P-Y-K-K-E-E-K-A-E-T-G-E-L-L-F-I-C-P-K-C-G-R-K-Y-T-L-D-E-A-E-M-Y-E-F-R-C-P-E-D-G-T-L-L-V-A-N-Q"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-I-F-S-T-M-A-K-E-F-R-Y-K-G-Y-T-L-Q-E-L-E-Q-M-S-L-E-E-L-A-K-I-M-P-A-R-Q-R-R-T-L-L-R-R-L-K-F-G-W-S-D-Q-Q-K-K-L-F-K-K-I-L-L-A-K-E-G-K-Y-K-K-P-I-K-T-H-A-R-N-T-I-I-L-P-F-M-V-G-V-T-V-H-V-Y-N-G-K-E-Y-V-P-V-Q-I-K-P-E-M-I-G-H-Y-L-G-E-F-S-F-T-T-K-R-P-K-H-S-A-P-G-I-G-A-T-R-S-S-A-H-V-S-K-K"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-Q-Y-K-I-N-M-Y-A-I-V-V-Y-D-V-N-V-S-R-Q-N-Q-I-R-E-F-L-R-K-Y-L-Y-H-V-Q-R-S-V-F-E-G-E-I-S-P-S-S-L-Y-Y-M-K-K-I-L-Q-S-Y-I-G-E-T-D-S-L-I-I-Y-V-L-R-D-K-S-C-L-M-D-K-I-V-L-G-E-D-K-D-L-Q-I-Y"} +{"text": "### FUNCTION Located on the platform of the 30S subunit ### SEQUENCE -M-A-K-E-R-W-G-V-A-H-I-Y-S-S-E-N-N-T-I-I-H-I-T-D-I-T-G-A-E-T-I-A-V-G-S-G-G-M-V-V-N-A-D-R-L-E-G-S-P-T-A-A-I-L-A-A-K-R-A-A-A-L-A-K-E-R-G-I-T-G-L-H-I-K-V-R-A-P-G-G-H-N-G-P-W-I-P-G-P-G-A-S-A-A-I-K-T-L-A-R-E-G-L-K-I-G-I-I-E-D-V-T-P-T-P-H-D-G-C-R-R-K-G-G-K-R-G-R-R-V"} +{"text": "### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-M-L-L-Q-T-E-K-A-L-R-L-L-E-Q-Y-N-T-I-T-I-L-V-P-R-E-Y-T-K-S-K-I-K-E-F-F-E-K-K-G-Y-K-V-K-K-V-N-T-L-I-T-K-K-G-L-K-K-A-Y-V-R-F-K-E-E-G-V-A-R-K-V-A-E-E-L-G-G-L"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-E-H-P-M-R-K-I-R-I-E-K-V-T-L-N-I-G-V-G-E-S-G-E-K-L-D-K-A-Y-E-L-L-K-R-L-T-G-Q-K-P-V-K-T-K-A-K-V-R-V-E-Q-W-H-I-R-P-G-L-P-I-G-V-K-V-T-L-R-G-E-K-A-Y-K-I-L-K-E-K-L-L-P-A-V-D-F-K-I-K-A-S-S-F-T-D-R-G-F-G-F-G-I-P-E-Y-I-M-I-P-G-M-K-Y-D-P-E-L-G-L-I-G-L-E-A-Y-V-T-L-E-R-P-G-Y-R-V-E-R-R-R-I-K-R-S-K-V-G-S-R-H-R-L-N-K-E-E-I-I-K-W-A-Q-E-E-L-G-V-Q-I-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-K-P-I-S-A-S-I-V-R-A-L-P-V-G-A-Y-L-N-V-A-D-N-S-G-A-K-V-V-K-L-I-A-V-K-G-Y-K-G-R-K-R-R-L-A-K-A-G-I-A-D-L-V-I-V-S-V-R-D-G-K-P-D-M-I-G-Q-I-F-K-A-V-V-V-R-M-K-K-E-W-R-R-R-D-G-T-R-I-K-F-E-D-N-A-V-A-L-L-K-D-D-Y-G-T-P-K-G-T-I-I-K-T-P-I-A-K-E-V-A-E-R-W-P-D-L-A-K-I-A-R-I-I-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-E-F-L-G-E-L-I-Y-D-A-E-G-L-V-L-G-R-L-A-S-I-V-A-R-N-L-K-R-G-Y-R-V-K-I-V-N-A-E-K-A-I-I-T-G-D-P-N-M-V-K-K-E-W-L-Q-K-V-K-R-G-D-Y-Y-K-G-P-F-Y-P-K-R-P-D-N-I-L-K-R-V-I-R-G-M-L-P-R-K-T-A-R-G-R-E-L-L-K-N-V-K-V-Y-I-G-V-P-E-E-L-K-D-K-P-K-L-G-L-N-L-E-N-A-K-G-Y-P-E-A-L-I-K-E-V-L-K-A-K-P-K-F-E-R-G-N-I-K-Y-I-E-L-G-E-L-S-K-Y-L-G-A-K-F-T"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-L-K-Q-S-G-H-K-H-G-K-L-L-K-I-L-K-H-N-K-P-K-E-R-K-F-G-K-G-A-R-R-C-E-R-C-G-R-Y-D-G-I-I-R-R-Y-G-L-Y-L-C-K-D-C-F-K-E-V-A-H-E-L-G-F-F-K-W-G-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-W-R-Q-R-R-K-W-E-G-P-S-H-P-W-Q-K-Q-R-L-I-I-E-K-R-L-M-K-E-Y-G-L-K-N-K-R-E-L-W-I-A-E-T-I-A-R-K-W-R-A-Y-A-R-Y-L-N-A-K-Q-A-A-G-Q-D-I-S-E-E-K-E-R-F-L-T-K-L-K-K-L-G-V-L-S-E-N-A-E-L-D-D-V-L-D-L-T-V-K-D-V-L-E-R-R-L-Q-T-M-L-V-R-K-G-L-A-K-T-M-K-Q-A-R-Q-F-I-V-H-G-H-I-M-V-N-G-E-V-V-D-A-P-S-Y-L-V-K-K-E-E-E-D-K-I-E-F-V-P-F-S-P-L-A-N-P-E-H-P-A-R-K-L-E-Q-K-E-E-T-N-E-E-S-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-A-R-D-I-V-A-D-F-L-S-H-L-T-N-V-R-R-K-G-E-D-K-T-A-F-F-P-V-S-N-L-I-I-K-L-V-E-I-M-K-R-E-G-Y-I-K-N-Y-R-L-V-D-S-S-R-G-K-I-I-E-I-E-L-S-E-Y-F-N-E-A-N-A-I-K-P-R-F-P-V-E-Y-S-E-L-E-K-Y-E-K-R-Y-L-P-A-L-N-F-G-R-L-I-L-S-T-S-K-G-L-I-T-N-R-E-A-K-E-Q-K-I-G-G-V-L-I-A-Y-V-Y"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-K-L-A-E-L-I-E-L-P-K-E-Q-C-N-D-K-K-C-P-H-H-G-H-L-K-V-R-G-F-F-F-K-G-K-V-I-K-K-S-D-N-K-T-V-K-I-E-I-I-R-Y-Y-W-L-P-K-Y-E-R-Y-E-L-R-R-T-R-I-T-A-Y-L-P-E-C-L-K-D-I-K-E-G-D-Y-V-L-I-G-E-T-R-P-L-S-K-T-K-H-F-V-V-L-G-K-L-K-K-G-I-A-L-T-Q"} +{"text": "### FUNCTION Catalyzes the reduction of arsenate ### SEQUENCE -M-E-N-K-K-T-I-Y-F-L-C-T-G-N-S-C-R-S-Q-M-A-E-A-W-G-K-K-Y-L-G-D-K-W-N-V-L-S-A-G-I-E-A-H-G-V-N-P-N-A-I-K-A-M-K-E-V-D-I-D-I-T-D-Q-T-S-D-I-I-D-R-D-I-L-D-K-A-D-L-V-V-T-L-C-G-H-A-N-D-V-C-P-T-T-P-P-H-V-K-R-V-H-W-G-F-D-D-P-A-G-Q-E-W-S-V-F-Q-R-V-R-D-E-I-G-A-R-I-K-K-Y-A-E-T-G-E"} +{"text": "### FUNCTION Involved in succinate export with YjjP Both proteins are required for export ### SEQUENCE -M-G-V-S-L-L-W-A-L-L-Q-D-M-V-L-A-A-I-P-A-L-G-F-A-M-V-F-N-V-P-V-R-A-L-R-Y-C-A-L-L-G-A-I-G-H-G-S-R-M-L-M-I-H-F-G-M-N-I-E-L-A-S-L-V-A-S-I-M-I-G-I-N-W-S-R-W-L-L-A-H-P-K-V-F-T-V-A-A-V-I-P-M-F-P-G-I-S-A-Y-T-A-M-I-S-V-V-E-I-S-H-L-G-Y-S-E-A-L-M-S-T-M-V-T-N-F-L-K-A-S-F-I-V-G-A-L-S-I-G-L-S-L-P-G-L-W-L-Y-R-K-R-P-G-V"} +{"text": "### FUNCTION Immunity protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition system CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion Protects cells against the CDI activity of CdiA, its cognate toxin protein, but not against non-cognate CdiA from Ecoli strains 563, EC93 or Ddadantii strain 3937 ### SEQUENCE -M-K-N-L-L-Y-V-V-L-L-M-A-V-C-I-L-G-L-L-I-V-G-T-I-F-Y-L-F-L-E-V-F-M-Y-F-Y-V-N-A-P-I-S-L-E-S-F-Q-F-T-R-L-L-K-M-S-I-Y-G-G-G-I-L-G-L-G-I-G-L-L-R-I-F-K-I-K-G-F"} +{"text": "### FUNCTION Participates in cysteine desulfuration mediated by SufS Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process ### SEQUENCE -M-A-G-L-P-D-R-D-K-L-I-R-N-F-S-R-C-L-N-W-E-E-K-Y-L-Y-I-I-E-L-G-G-Q-L-A-P-L-T-E-Q-Q-R-H-P-E-N-L-I-S-G-C-Q-S-Q-V-W-I-A-M-T-L-S-A-E-G-H-V-I-F-A-G-D-S-D-A-A-I-V-K-G-L-V-A-V-V-F-I-L-Y-H-D-L-T-P-Q-Q-I-I-S-L-D-V-R-P-F-F-A-D-L-A-L-S-Q-H-L-T-P-S-R-S-Q-G-L-E-A-M-I-R-A-I-R-T-K-V-A-N-L-S-A-H"} +{"text": "### FUNCTION Involved in resistance toward heavy metals ### SEQUENCE -M-S-D-S-D-A-M-T-D-P-N-A-V-S-Y-S-N-A-I-V-V-L-C-T-A-P-D-E-A-S-A-Q-N-L-A-A-Q-V-L-G-E-K-L-A-A-C-V-T-L-L-P-G-A-T-S-L-Y-Y-W-E-G-K-L-E-Q-E-Y-E-V-Q-L-L-F-K-S-N-T-D-H-Q-Q-A-L-L-T-Y-I-K-Q-H-H-P-Y-Q-T-P-E-L-L-V-L-P-V-R-D-G-D-K-D-Y-L-S-W-L-N-A-S-L-L"} +{"text": "### FUNCTION The GINS complex plays an essential role in the initiation of DNA replication ### SEQUENCE -M-G-Y-Y-D-L-D-D-I-L-A-D-S-S-K-F-A-C-R-F-N-Y-E-L-P-G-L-G-Y-L-E-G-N-P-G-K-P-V-G-K-H-S-K-V-E-L-P-L-W-L-A-S-V-L-A-T-V-T-G-E-Q-E-H-V-D-E-E-A-L-P-F-V-E-F-L-P-P-E-M-F-S-A-R-V-V-N-A-I-K-A-D-A-P-T-L-D-V-H-S-I-N-G-H-F-Y-A-L-G-T-R-W-A-A-L-F-S-D-A-G-L-A-G-M-L-A-G-M-V-L-E-R-A-L-E-V-Q-R-H-A-A-S-A-A-V-E-A-T-A-P-T-D-A-T-A-R-M-L-Q-T-L-D-E-W-E-R-Q-L-Y-R-R-A-H-A-A-S-R-D-A-K-L-W-A-A-R-R"} +{"text": "### FUNCTION Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein residues may serve to stabilize the conformation of rRNAs The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA ### SEQUENCE -M-H-L-M-Y-T-L-G-P-D-G-K-R-V-Y-T-L-E-K-V-T-P-S-G-E-I-T-K-S-A-H-P-A-R-F-S-P-D-D-K-Y-S-R-Q-R-V-T-L-K-R-R-F-D-M-L-P-R"} +{"text": "### FUNCTION Component of the signal peptidase complex which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum Dispensable for SPC enzymatic activity ### SEQUENCE -M-E-I-F-N-D-L-S-R-K-L-V-F-P-I-D-Y-P-S-Q-R-R-V-A-K-L-T-D-I-I-L-G-S-G-T-L-V-S-C-L-L-G-F-Y-A-G-S-L-S-L-T-L-Y-A-F-A-A-A-Y-G-L-A-L-L-L-V-V-P-A-Y-G-K-Y-R-Q-Q-K-L-A-W-V-G-S-A-A-A-T-T-K-D-L"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-S-N-Q-V-L-L-D-K-L-D-R-T-T-E-S-L-S-Q-A-L-A-Q-L-V-K-L-S-S-I-D-R-A-S-A-D-S-D-G-D-N-D-G-T-T-D-S-I-T-S-V-A-T-N-G-V-M-M-V-H-A-H-T-T-Q-L-I-R-G-V-Q-D-L-L-V-I-T-R-A-I-R-E-T-W-V-L-G-Q-I-P-K-K-N-G-D-E-D-A-I-D-Y-E-K-C-E-R-L-L-E-K-A-M-D-D-F-F-G-P-V-A-L"} +{"text": "### FUNCTION Required for efficient biogenesis of the 60S ribosomal subunit ### SEQUENCE -M-S-T-E-I-S-A-A-A-P-R-R-A-A-N-G-K-K-R-A-N-R-R-K-K-R-R-T-Q-A-E-S-D-S-S-D-S-S-D-S-S-E-S-S-Q-P-S-A-D-E-Q-E-A-K-T-D-D-V-A-V-E-L-S-D-V-E-L-S-D-S-E-N-K-T-V-S-H-S-E-K-L-D-D-E-S-K-A-K-L-K-S-I-Q-L-T-A-T-D-L-S-S-K-F-A-L-Q-Q-N-R-N-I-D-L-Q-K-A-G-R-E-V-D-H-G-L-E-K-L-A-K-L-D-A-Q-T-S-E-Q-E-S-G-R-L-K-T-G-Y-I-N-M-L-F-E-H-V-G-E-D-V-N-Q-L-R-N-A-P-D-F-T-P-K-S-L-V-V-L-A-N-A-L-K-D-G-G-D-M-F-D-I-E-S-L-R-A-L-V-D-N-K"} +{"text": "### FUNCTION Component of the general transcription and DNA repair factor IIH of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription ### SEQUENCE -M-P-R-A-R-K-G-A-L-V-Q-C-D-P-S-I-R-A-L-I-L-Q-I-D-S-G-T-H-D-I-I-W-E-E-L-D-E-T-H-L-L-V-D-P-A-K-V-S-Y-I-K-E-K-L-N-W-F-L-S-K-N-I-Y-N-P-S-E-E-E-E-N-P"} +{"text": "### FUNCTION Golgi membrane protein involved in vesicular trafficking ### SEQUENCE -M-S-E-N-D-Q-K-G-V-K-F-I-R-A-L-L-V-T-T-G-A-V-A-T-L-G-F-L-V-Q-L-S-E-V-A-S-E-F-L-A-A-A-R-A-C-F-G-L-P-L-S-V-L-L-V-Y-L-E-F-R-P-V-P-L-L-Q-Q-Y-A-S-F-Y-Y-S-Y-M-G-R-A-L-L-Q-L-L-L-A-V-M-L-L-P-A-G-F-F-Q-V-C-A-F-T-M-L-F-M-T-G-F-I-C-A-A-L-E-L-S-S-S-A-P-E-L-P-S-F-R-N-D-G-R-A-L-S-I-G-A-E-E-D-D-D-M-I"} +{"text": "### FUNCTION Stimulates the activity of serine palmitoyltransferase ### SEQUENCE -M-M-A-A-D-D-T-M-S-S-K-R-A-D-N-C-Y-K-K-D-R-G-T-M-V-Y-T-P-T-D-A-Q-Q-A-T-G-K-V-H-E-K-V-Y-K-F-F-E-S-L-Y-W-M-Y-Y-I-H-L-P-Y-Y-L-M-T-S-F-D-S-F-C-L-H-V-F-F-L-V-V-F-T-L-S-L-F-G-L-L-K-W-V-L-S-L-Y-W-A-T-V-G-Y-M-A-Y-A-A-T-G-Q"} +{"text": "### FUNCTION Golgi membrane protein involved in vesicular trafficking ### SEQUENCE -M-A-L-S-W-K-S-F-V-N-V-P-G-I-L-A-D-L-R-S-F-N-F-S-V-Y-G-R-W-F-G-Y-I-N-I-L-L-C-L-A-L-G-I-A-N-I-F-H-F-S-I-V-I-A-F-A-I-V-A-I-V-Q-G-L-L-L-I-F-V-E-V-P-I-L-L-K-I-C-P-L-S-D-N-F-I-G-L-V-K-K-C-D-T-N-G-R-R-T-L-L-Y-T-A-L-A-I-V-Q-Y-A-S-L-S-V-Q-V-T-S-L-L-A-V-A-I-G-L-T-I-S-A-I-F-Y-G-T-G-Y-L-K-K-Q-E-F-L-E-G-N-V-I-R-N-P-T-D-P-A-F-M-R-E-A-A-V-R-E-V-L"} +{"text": "### FUNCTION Component of the COP9 signalosome ### SEQUENCE -M-I-R-Q-E-V-L-H-A-V-L-D-P-K-A-V-H-F-K-Q-F-W-L-S-S-V-D-R-D-E-S-E-L-L-E-V-L-C-F-G-N-Y-G-D-L-N-A-I-Q-S-C-E-E-W-K-D-A-I-E-S-K-L-R-T-L-T-L-L-G-L-C-E-V-P-S-E-L-E-Y-D-Q-A-M-A-S-C-C-I-P-D-D-V-I-L-E-Q-R-M-V-E-L-Q-A-Q-V-H-F-Q-L-D-S-V-G-R-R-I-K-V-L-R-C-L-G-A-R-D-I-Y-N-G-E-R-P-L-L-L-L-R-D-A-A-R-S-R-E-S-T-L-A-G-L-R-Q-W-K-Q-K-L-Q-Y-Q-L-R"} +{"text": "### FUNCTION Involved in pre-mRNA splicing ### SEQUENCE -M-T-T-S-H-R-P-Q-L-E-A-R-S-G-T-K-S-G-V-A-G-E-Y-V-P-T-G-V-K-H-A-R-L-L-P-G-H-R-T-V-K-R-R-R-E-G-G-A-T-A-E-D-E-E-R-E-R-A-G-A-E-T-R-T-V-D-C-N-E-G-T-D-E-L-A-G-E-G-R-S-A-G-S-G-D-G-D-E-A-S-S-A-E-D-S-S-D-A-D-D-E-D-D-V-D-N-P-E-E-L-R-R-E-L-E-A-L-R-A-S-K-T-G-A-K-T-G-A-K-T-G-A-K-T-G-E-K-G-A-G-G-G-G-W-R-A-G-A-V-F-G-R-Q-K-R-R-R-E-Q-A-E-G-R-A-Y-R-N-D-V-T-Q-S-E-Y-H-Q-D-F-L-R-R-L-T-K"} +{"text": "### FUNCTION As part of the CRL3 E3 ubiquitin ligase complex ### SEQUENCE -M-T-P-T-S-H-V-T-L-V-S-S-D-G-K-S-F-E-V-P-R-E-R-A-M-L-S-P-T-L-A-K-M-L-D-S-S-F-A-E-A-K-E-A-K-V-T-L-P-T-I-E-S-S-M-L-A-K-V-V-E-Y-L-E-Y-L-E-E-Y-K-H-K-D-D-G-E-D-I-P-Q-F-E-V-P-P-E-I-S-L-E-L-L-L-A-A-D-Y-L-Q-I"} +{"text": "### FUNCTION Involved in pre-mRNA splicing May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome May do so by stabilizing the catalytic center or the position of the RNA substrate ### SEQUENCE -M-S-Y-N-G-I-G-L-K-T-A-K-G-S-S-T-S-G-H-I-Q-R-S-L-A-D-N-Q-A-G-N-V-K-N-F-S-S-R-K-E-E-S-Q-G-R-V-A-R-A-S-R-E-R-K-L-D-G-S-M-A-A-H-A-D-R-R-E-I-E-V-R-V-S-E-L-R-D-E-L-E-D-A-D-I-D-A-E-E-I-E-R-R-C-E-Q-L-R-R-Q-L-Q-S-E-A-A-E-R-A-R-V-A-Q-A-Y-T-P-R-N-A-R-S-A-G-A-T"} +{"text": "### FUNCTION Component of the ceramide synthase complex required for synthesis of ceramides ### SEQUENCE -M-A-I-G-R-Y-G-T-L-V-F-Y-I-L-A-G-L-A-F-V-W-S-L-E-Y-F-K-H-Y-T-K-N-N-Y-E-R-F-H-C-T-A-V-V-E-P-V-Q-G-T-A-T-V-E-K-L-S-A-V-G-G-P-P-C-D-K-R-A-E-L-K-L-I-T-Q-K-L-T-Q-H-F-D-P-N-K-Q-P-A-L-F-C-I-V-E-N-T-S-V-E-S-V-H-Y-P-V-S-R-T-N-K-G-P-A-G-Y-I-A-Y-A-G-Y-E-A-D-R-A-A-V-H-K-Y-C-E-A-H-G-A-A-V-L-H-M"} +{"text": "### FUNCTION Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane ### SEQUENCE -M-S-G-Q-L-E-V-S-A-P-S-R-S-I-L-N-D-K-W-D-V-V-L-S-N-L-V-V-K-T-G-L-G-F-G-A-G-V-F-A-S-V-L-F-F-K-R-R-A-F-P-V-W-L-G-V-G-F-G-L-G-R-G-Y-A-E-G-D-A-I-F-R-S-H-A-G-L-R-A-V-R-A"} +{"text": "### FUNCTION Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase , that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c ### SEQUENCE -M-P-Q-S-F-S-S-I-V-R-M-G-D-Y-I-L-K-S-P-T-L-S-K-I-A-V-P-V-A-Q-Q-F-V-K-L-S-G-Y-R-Q-L-G-L-K-F-D-D-L-I-A-E-E-N-D-I-V-Q-T-A-L-R-R-L-P-E-E-E-S-Y-A-R-V-F-R-I-I-Q-A-H-Q-L-E-L-T-H-H-L-L-P-K-H-K-W-T-K-P-E-E-D-K-S-Y-L-L-P-Y-L-L-E-A-E-A-A-A-K-E-K-L-E-L-D-A-L-E-L-K"} +{"text": "### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase to ubiquinol Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants May act together with SDHAF1 ### SEQUENCE -M-R-T-T-N-H-L-Y-R-T-V-H-R-Q-G-K-P-L-L-P-P-L-H-L-Y-R-R-I-L-R-A-H-R-T-F-P-P-A-Q-R-A-L-G-D-E-Y-V-K-S-E-F-K-L-H-K-N-I-D-N-P-V-H-I-I-G-F-L-A-S-W-Q-D-Y-F-H-M-I-S-T-N-S-W-A-E-G-T-L-S-K-S-L-V-D-Q-M-S-S-E-Q-I-V-Q-L-Y-E-L-M-K-E-T-K-Q-L-G-G-A-S-A-E-S-G-S-S-L-S"} +{"text": "### FUNCTION Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2 ### SEQUENCE -M-D-G-S-H-Y-D-I-L-G-I-A-V-D-A-E-P-L-E-V-R-Q-A-Y-R-Q-R-L-L-E-A-H-P-D-K-Q-G-G-V-D-K-G-A-V-T-R-I-Q-Q-A-Y-R-V-L-S-D-P-T-Q-R-S-A-Y-D-G-E-L-A-V-Q-I-A-A-T-G-V-H-G-R-A-D-A-L-D-E-H-S-L-D-D-F-E-Y-N-E-Q-Q-G-V-F-T-M-A-C-P-R-C-S-S-A-E-G-F-E-L-P-E-Q-A-L-E-E-N-A-T-A-R-P-G-G-G-M-Q-V-I-V-Q-C-A-A-C-S-L-W-L-K-V-D-F-D-I-V-Y-T-S-E"} +{"text": "### FUNCTION Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane ### SEQUENCE -M-P-R-L-L-R-Y-G-S-F-S-V-V-A-S-V-L-G-A-S-Y-Y-Y-Y-A-V-A-S-P-L-Y-T-E-A-E-W-H-R-V-S-Q-R-T-A-A-L-I-D-R-R-I-D-I-P-V-P-E-S-T-T-E-R-R-E-Y-V-V-R-S-S-K-E-T-M-K-D-I-W-N-E-Q-I-R-S-I-V-D-W-I-Y-S-W-S-H"} +{"text": "### FUNCTION Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP pathway ### SEQUENCE -M-S-S-D-W-D-T-N-T-V-I-G-Q-R-V-R-T-G-G-S-G-P-R-Q-Q-V-A-R-T-Q-G-Q-I-N-A-A-R-R-A-G-L-V-L-S-V-D-K-K-Y-A-S-S-N-T-K-A-N-N-E-G-Q-R-L-T-M-V-D-R-E-T-D-I-V-K-P-K-K-L-D-P-S-V-G-R-A-I-A-K-G-R-G-D-K-G-M-T-Q-K-D-L-A-T-R-I-N-E-K-P-T-V-I-N-D-Y-E-A-G-R-A-I-P-N-Q-Q-I-L-A-K-M-E-R-A-L-G-V-K-L-R-G-K-G-I-G-E-P-L-G-G-P-K-K-K"} +{"text": "### FUNCTION Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit ### SEQUENCE -M-A-V-K-N-L-E-K-G-I-N-V-S-G-R-V-W-K-S-E-K-D-A-F-R-A-T-S-K-V-I-K-N-K-K-L-T-S-W-E-L-K-R-E-Q-R-Q-L-D-Q-Q-F-K-E-R-M-N-A-L-K-N-E-K-E-E-E-R-Q-Q-R-I-K-A-L-R-E-R-R-E-K-K-E-E-K-E-R-Y-E-R-L-A-A-R-M-H-A-K-K-V-E-R-M-R-R-R-E-K-R-N-K-A-L-K-E-R"} +{"text": "### FUNCTION The complex LTO1YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly complex machinery May be required for biogenesis of the large ribosomal subunit and initiation of translation ### SEQUENCE -M-S-C-E-D-D-W-L-N-T-S-D-D-E-E-K-H-G-V-F-G-G-G-S-L-E-L-Q-K-L-E-R-T-H-R-N-R-G-Y-R-D-G-I-S-S-A-K-E-E-N-L-Q-E-G-F-D-M-K-F-P-E-G-S-R-L-G-F-Q-V-G-E-V-I-G-K-L-Q-T-L-D-S-L-F-G-A-Q-D-S-E-L-R-S-D-Y-K-E-A-L-A-Q-L-Q-I-S-R-V-L-T-H-A-N-F-S-E-Q-M-D-A-T-E-A-L-S-S-L-L-A-R-W-E-G-A-L-V-K-Y-T-S-R-Y-I-P-N-V"} +{"text": "### FUNCTION Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 ### SEQUENCE -M-S-T-S-S-R-A-L-A-A-Y-R-N-A-L-R-A-T-K-V-A-F-G-E-D-V-R-M-L-V-A-A-R-K-A-M-R-H-G-M-L-A-P-D-A-S-L-P-V-E-D-Q-I-T-H-M-N-D-I-A-T-F-L-R-R-N-L-V-Q-G-K-K-V-S-G-K-D-D-V-Y-Q-L-R-I-H-E-E-T-E-L-G-D-N-A-T-I-K-E-T-K-T-T-L-A-S-Q-G-G-G-C-C-G-G-G-K-D-L-Y-K"} +{"text": "### FUNCTION Involved in pre-mRNA splicing ### SEQUENCE -M-G-I-E-D-I-N-R-R-L-R-Q-L-K-K-K-R-V-D-A-S-I-R-N-R-K-E-A-A-S-E-E-R-A-R-L-A-E-G-K-P-R-V-Y-S-M-A-E-E-P-A-D-E-A-E-A-D-D-T-Q-S-E-Q-L-K-L-L-N-Y-R-I-A-D-Y-E-K-W-D-E-K-Q-K-R-H-K-Q-P-S-D-G-A-D-L-G-E-L-A-N-S-T-Y-R-S-E-L-H-Q-L-H-R-R-G-V-V-K-G-R-A-T-N-G-R-I-S-A-S-G-K-V-V-L-D-D-E-P-E-L-V-E-K-L-A-A-A-V-Q-Q-T-A-K-R-R-H-E-E-R-Q-K-K-A-A-K-D-G-G-R-A-T-A-G-S-L-N-D-K-N-R-H-F-N-E-K-L-D-R-E-F-R-K-R-G-Q"} +{"text": "### FUNCTION Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 ### SEQUENCE -M-D-H-T-L-H-L-H-V-P-F-E-S-A-R-L-A-D-I-A-A-R-A-L-A-P-D-P-L-L-R-P-E-E-L-S-V-S-F-A-S-D-G-A-S-L-N-I-K-L-A-A-I-D-A-R-V-L-R-V-A-T-N-S-I-F-E-A-L-K-T-V-V-E-T-A-D-E-L-D-F"} +{"text": "### FUNCTION May be involved in cellular response to stress Required to maintain mitochondrial DNA ### SEQUENCE -M-S-S-F-F-K-F-Y-K-A-S-L-Q-S-H-P-K-R-T-N-A-L-T-T-G-F-L-F-G-L-G-D-I-V-A-Q-T-Q-F-P-E-P-G-A-S-Y-D-P-M-R-T-L-R-P-F-L-Y-G-A-V-L-F-S-L-V-G-D-K-W-Y-R-F-L-S-T-V-R-L-G-R-L-P-Q-A-H-W-A-N-V-L-A-R-V-A-C-D-Q-L-I-F-A-P-I-G-V-P-L-Y-Y-T-A-M-A-L-M-E-G-G-S-L-E-D-V-R-I-R-L-S-E-K-W-W-S-T-L-L-A-N-W-I-V-W-P-A-F-Q-L-C-N-F-S-L-V-P-V-Q-H-R-L-L-T-V-N-V-L-S-I-F-W-N-T-Y-L-S-Y-S-N-S-T-A-S-S"} +{"text": "### FUNCTION Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner In the complex, it is required to regulate activity of mtHSP70 ### SEQUENCE -M-A-H-R-V-L-V-Q-V-I-F-T-G-A-R-V-F-G-R-A-F-T-E-A-Y-K-Q-T-A-A-Q-M-A-K-Q-G-T-S-S-A-A-R-S-Q-G-G-M-T-N-E-Y-G-G-I-T-L-D-E-S-C-K-I-L-N-I-E-E-N-G-P-E-M-N-L-D-K-V-E-Q-R-F-K-Y-L-F-D-I-N-D-K-E-K-G-G-S-F-Y-L-Q-S-K-I-Y-R-A-A-E-R-L-K-W-E-L-A-Q-R-E-Q-A-D-K-G-A-S-A-H-P-Q-D-Q-Q-P-G-P-Q-N"} +{"text": "### FUNCTION Component of the biogenesis of lysosome-related organelles complex-1 involved in endosomal cargo sorting ### SEQUENCE -M-S-D-D-V-D-S-E-T-R-S-R-T-P-S-I-S-S-R-Q-F-I-I-P-E-D-E-L-A-T-L-D-S-E-N-S-S-L-D-S-G-G-E-E-A-S-S-G-G-S-D-A-Y-S-A-A-G-G-S-T-P-V-F-S-R-L-G-Q-H-P-S-T-F-F-T-G-S-Q-V-A-P-I-F-D-T-S-L-Y-L-F-E-S-L-T-Q-S-L-D-S-V-D-F-S-E-A-L-S-L-Q-T-K-T-S-A-T-I-N-S-K-S-R-E-L-Q-L-L-V-G-E-V-Q-T-H-L-R-R-L-Q-T-A-F-E-Q-G-Q-H-T-A-Q-R-V-R-H-N-L-R-D-I-T-R-G-V-E-S-L-K-Q-T-F-A-R-S-Y-P-I-E-Y-H-Q-A-L-E-R-A-Y-E-R-R-A-E"} +{"text": "### FUNCTION Involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit Accompanies the pre-60S particles to the cytoplasm ### SEQUENCE -M-P-S-K-N-S-I-N-R-P-K-Q-K-L-N-L-Q-H-R-V-Q-K-N-A-A-K-R-S-A-R-E-R-A-G-L-L-A-P-P-R-S-S-D-Q-S-Q-S-G-R-A-K-S-I-P-L-D-L-F-R-G-E-R-V-D-Q-G-P-I-T-T-K-T-L-S-K-K-R-A-K-K-I-E-R-N-L-R-Y-V-E-Q-R-K-L-L-V-D-V-Q-A-A-R-E-S-G-M-D-I-D-V-E-T-A-V-S-T-K-A-K-T-Q-Q-T-G-P-L-Q-K-V-K-E-S-I-W-S-A-L-E-D-V-A-A-Q-E-M-I-V-Q-T-G-A-G-T-T-L-G-G-Q-F-F-P"} +{"text": "### FUNCTION Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules ### SEQUENCE -M-S-L-L-R-T-L-Q-M-Q-P-R-V-I-T-V-F-A-E-H-A-N-V-G-A-A-S-E-I-L-G-A-L-K-T-A-S-G-P-K-C-K-V-Q-V-S-T-M-F-P-T-L-E-Q-L-I-Y-M-S-E-I-N-R-T-A-V-A-A-Q-V-P-R-L-S-E-L-L-Q-K-P-S-F-S-E-E-F-S-S-P-L-A-Q-C-T-Q-D-G-V-W-R-S-Q-G-G-L-W-V-D-W-E-K-R-L-L-G-A-D-G-Q-S-V-H-E-L-L-G-S-S-T-M-T-I-D"} +{"text": "### FUNCTION Additional factor that functions in concert with eIF-2 and the initiator tRNA in directing the ribosome to the proper start site of translation ### SEQUENCE -M-S-I-E-N-L-K-S-F-D-P-F-A-D-T-G-D-D-E-A-S-S-S-N-Y-I-H-I-R-I-Q-Q-R-N-G-R-K-T-L-T-T-V-Q-G-I-P-E-E-Y-D-L-K-R-I-L-K-V-L-R-K-D-F-G-C-N-G-N-M-V-K-D-D-E-M-G-E-I-I-Q-L-Q-G-D-Q-R-A-K-V-C-E-F-L-I-T-Q-L-A-I-P-K-K-N-I-K-I-H-G-F"} +{"text": "### FUNCTION Involved in export of poly ### SEQUENCE -M-S-V-D-E-H-L-N-Q-G-T-G-E-K-Q-Y-R-R-R-D-L-R-N-G-L-A-S-R-M-G-L-G-E-S-T-Y-R-A-R-E-Y-G-P-S-R-R-S-R-F-R-D-R-R-D-A-R-P-P-P-P-T-H-Q-R-V-R-F-L-N-I-P-L-D-V-S-D-Y-E-I-D-D-L-L-K-D-L-P-K-P-L-Y-S-K-F-Y-D-H-E-D-S-R-S-A-V-F-E-F-E-D-H-S-I-L-D-K-C-V-E-L-Y-N-G-L-E-L-H-G-A-K-I-T-V-E-I-F-E-Q-Q-G-R-F-A-D-S-T-R-T-N-R-S-T-D-H-V-E-K-E-A-G-F-K-T-G-R-P-R-G-K-A-R-A-T-K-K-E-K-P-P-Q-P-T-L-E-D-L-D-A-E-L-D-A-Y-M-N-G-N"} +{"text": "### FUNCTION Forms a chaperone-bound H2AZ-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2AZ histone replacement in chromatin ### SEQUENCE -M-A-E-K-A-A-E-K-A-E-Q-R-A-A-D-E-A-E-K-R-P-V-E-D-G-E-K-H-S-G-R-K-R-R-R-R-N-Y-D-E-H-D-E-A-V-A-K-D-D-A-Q-S-A-K-A-G-A-A-A-D-S-D-A-D-D-S-D-A-D-D-E-K-L-E-V-L-M-A-R-E-E-E-D-E-D-D-L-A-E-I-D-A-S-N-I-I-S-G-G-R-R-T-R-G-K-V-I-D-Y-K-Q-T-A-E-E-L-A-A-E-G-A-A-A-G-V-D-D-D-A-E-D-A-D-A-D-F-D-G-E-G"} +{"text": "### FUNCTION Component of the biogenesis of lysosome-related organelles complex-1 , a complex involved in endosomal cargo sorting ### SEQUENCE -M-N-P-S-E-V-A-S-A-G-I-H-P-I-E-L-C-V-H-S-I-L-S-S-N-L-E-G-I-Y-Q-A-I-T-E-L-R-E-S-Q-A-L-L-V-M-K-F-N-Q-V-K-K-S-F-M-D-E-Q-E-L-L-Q-E-E-G-S-L-K-E-E-L-A-R-V-N-Q-L-K-K-R-L-D-K-L-T-E-L-Y-A-E-L-A-R-K-C-G-A-L"} +{"text": "### FUNCTION Plays a role in starvation-induced autophagy Involved in mitophagy Functions with ATG17 and ATG29 at the preautophagosomal structure ### SEQUENCE -M-E-P-F-V-I-T-A-S-E-C-D-C-N-S-A-H-S-S-R-V-S-K-D-G-Y-A-L-S-D-E-L-S-N-E-T-M-F-L-T-Q-V-K-Y-I-F-E-G-E-E-D-H-I-D-D-N-T-M-Q-E-I-N-T-D-I-V-N-V-V-I-V-E-L-D-E-T-L-E-I-K-N-V-E-L-I-S-D-E-Y-Q-L-L-G-F-S-N-D-A-D-N-D-L-N-L-T-I-L-S-E-F-P-A-D-V-S-P-G-T-R-D-L-G-K-L-V-T-R-Y-Q-H-Q-N-K-H-L-K-H-M-L-Q-E-L"} +{"text": "### FUNCTION Involved in ribosome biogenesis, probably through modulation of rDNA transcription ### SEQUENCE -M-K-Q-R-V-A-V-R-E-R-D-R-L-Q-E-K-E-R-L-R-R-Q-R-Q-R-A-E-R-E-A-R-Q-Q-A-S-Q-A-E-Q-E-A-K-L-A-A-L-E-R-H-Q-E-T-G-R-L-T-K-E-E-K-R-Y-L-N-K-R-T-R-Q-G-A-A-R-A-R-T-W-D-L-D-E-D-E-A-D-E-A-A-A-L-Q-S-Q-I-L-D-R-I-G-S-A-S-G-A-G-R-V-R-K-Q-R-R-A-R-I-R-E-A-L-P-K-A-S-E-D-R-R-Y-A-G-L-T-P-G-L-A-P-V-G-M-S-D-E-E-S-S-D-E-E-L-S-D-E-E-D"} +{"text": "### FUNCTION Acts as an inhibitor of cap-dependent translation Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA ### SEQUENCE -M-A-K-Y-T-E-E-E-L-L-Q-L-K-P-T-Y-D-V-A-V-N-F-D-V-D-A-F-K-A-M-I-A-E-V-A-E-H-H-E-I-A-D-L-F-H-Q-K-A-R-R-R-S-S-H-H-H-G-V-K-P-K-I-K-A-H-K-P-R-I-T-T-D-D-D-G-W-C-T-S-T-R-K-T-S-V-V-A-V-G-D-D-G-E-P-S-P-A-F-V-A-Q-E-T-L-R-V-K-P-N-N-K-N-I-A-S-S-R-P-A-D-T-R-D-I-V-A-D-K-P-T-M-S-F-N-A-F-A-A-L-E-S-D-D-E-D-Q-F"} +{"text": "### FUNCTION Component of the biogenesis of lysosome-related organelles complex-1 , a complex that is involved in endosomal cargo sorting ### SEQUENCE -M-V-A-E-A-G-A-S-I-Q-A-E-D-V-N-N-D-P-F-R-V-D-Q-L-I-L-D-Y-D-Y-M-L-Y-R-I-K-D-H-V-A-S-I-H-L-A-T-T-E-L-C-R-K-Q-N-Q-L-V-C-T-G-I-V-E-E-I-I-D-S-N-I-K-N-V-R-E-L-L-T-K-C-K-E-L-E-T-Y-F-E-Q-L-H-A-I-D-G-I-V-S-T-F-H-E-R-M-D-E-I-V-K-Q-Y-R-D-I-K-V-H-T-D-S-A-S-R-D-H-V-A-T-K"} +{"text": "### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit of the SDH catalytic dimer ### SEQUENCE -M-L-R-F-S-F-S-H-A-F-A-G-S-Y-G-L-A-P-A-R-A-T-R-F-Y-P-R-I-L-P-F-A-A-R-A-Y-S-A-D-K-Q-G-D-D-V-I-L-R-V-K-V-A-P-I-K-R-N-N-E-T-L-E-Q-Q-R-A-R-L-V-Y-Q-S-R-K-R-G-I-L-E-T-D-L-L-L-S-G-F-A-A-K-Y-L-K-H-M-T-A-E-E-L-N-E-Y-D-E-L-L-N-E-L-D-W-D-I-Y-Y-W-A-T-K-N-S-D-A-S-P-L-P-E-K-W-Q-H-S-K-I-L-R-K-L-Q-A-Y-S-E-N-K-D-K-Q-I-L-K-M-P-D-L-S-E-F"} +{"text": "### FUNCTION Involved in mitochondrial genome encoded proteins translation ### SEQUENCE -M-P-G-R-T-P-T-Y-K-L-P-P-L-P-R-L-K-V-K-K-P-V-I-K-Q-E-A-N-R-C-L-V-L-M-S-N-L-L-Q-C-W-S-S-N-G-H-M-N-P-V-C-E-K-L-A-T-D-L-K-A-C-T-S-Q-N-V-M-G-S-N-Q-K-P-R-K-S-T-I-N-Y-H-A-A-R-L-Y-D-R-I-S-G-K-P-H-D"} +{"text": "### FUNCTION Mediates the nuclear localization of the ribonucleotide reductase ### SEQUENCE -M-C-L-Y-V-N-K-E-H-P-Y-T-Q-A-S-G-P-W-P-A-C-L-P-R-R-W-Q-L-Y-K-D-Q-R-R-L-H-R-P-G-G-R-R-P-M-S-T-S-D-S-H-L-G-S-P-R-K-R-Q-L-Q-R-A-A-P-A-A-P-Q-H-S-E-Y-Q-Q-Q-L-S-T-L-G-M-R-I-R-Q-A-V-D-N-G-Y-R-A-P-Q-D-P-V-R-A-A-V-P-H-A-V-P-A-A-A-C-V-Q-D-N-T-L-Y-T-V-P-D-Y-K-R-V-P-L-A-A-D-R-A-P-P-M-L-V-N-Q-R-T-V-S-S-T-S-S-L-Q-A-W-E-S-Q-L-D-E-R-L-S-L-I-D-S-S-I-M-H-N-K-L-G-A-G-E-F-M-L-G-G-T-K-R-A-F-D-Q-L-E-T-D-N-W"} +{"text": "### FUNCTION Component of the biogenesis of lysosome-related organelles complex-1 , a complex involved in endosomal cargo sorting ### SEQUENCE -M-E-L-D-Q-D-V-N-R-I-I-K-S-K-T-A-T-K-V-S-A-M-Q-A-E-I-E-A-N-H-A-Y-I-Y-D-V-Q-L-K-K-L-L-R-L-H-D-E-E-L-Q-E-R-C-H-T-P-L-R-K-L-Y-A-K-Y-S-S-R-A-E-G-N-R-D-L-Q-T-W-A-E-H-V-E-R-D-L-R-L-L-E-T-T-L-R-L-V-R-E-G-K-A-Q-D-T-E-Q-A-P-G-K-G-D-R-I-F-R-S-D"} +{"text": "### FUNCTION Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling ### SEQUENCE -M-E-Y-K-Y-N-V-T-L-L-L-L-Q-V-V-L-H-R-Q-Q-E-L-A-H-Q-D-K-T-L-S-Q-I-S-L-L-R-E-P-V-V-D-T-A-V-L-E-R-F-S-A-H-R-V-V-R-L-Y-A-P-E-L-C-G-L-R-L-E-E-L-Q-A-V-V-R-E-V-F-A-R-G-L-A-G-S-A-E-D-T-P-V-T-L-I-T-L-A-N-H-Y-Y-R-L-R-V-Q-E-L-E-L-Q-E-L-P-K-L-K-E-L-M-E-S-A-A-G-L-R-T"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-D-A-L-N-S-R-E-Q-Q-E-F-Q-R-V-V-E-Q-K-Q-M-K-D-F-M-R-L-Y-S-N-L-V-E-R-C-F-S-D-C-V-N-D-F-T-S-S-K-L-T-S-K-E-Q-T-C-I-M-R-C-S-E-K-F-L-K-H-S-E-R-V-G-Q-R-F-Q-E-Q-N-A-A-L-N-Q-S-M-G-R"} +{"text": "### FUNCTION Common component of the spliceosome and rRNA processing machinery In association with the spliceosomal U4/U6U5 tri-snRNP particle, required for splicing of pre-mRNA In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA ### SEQUENCE -M-S-S-T-P-N-P-K-A-F-P-L-A-D-A-A-L-T-Q-Q-I-L-D-V-V-Q-Q-A-S-N-M-R-Q-L-K-K-G-A-N-E-A-T-K-T-L-N-R-G-I-S-E-F-I-I-M-A-A-D-C-E-P-I-E-I-L-L-H-L-P-L-L-C-E-D-K-N-V-P-Y-V-F-V-P-S-R-V-A-L-G-R-A-C-G-V-S-R-P-V-I-A-A-S-I-T-T-N-D-A-S-A-I-K-S-Q-I-Y-A-V-K-D-K-I-E-T-L-L-I"} +{"text": "### FUNCTION Required for assembly of cytochrome c oxidase ### SEQUENCE -M-L-E-P-S-R-Y-Q-D-P-R-T-W-K-M-T-P-A-M-I-R-A-R-R-P-Y-I-R-G-N-L-F-G-L-V-T-L-L-G-V-A-G-G-I-Y-V-Y-T-Y-R-A-L-H-K-D-D-D-F-A-D-V-P-I-P-P-V-S-E-E-E-L-R-Q-L-R-Q-E-Y-E-L-H-K-K-Q-R-A-A-E-R"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-D-Q-Q-D-L-N-K-L-Q-T-N-L-S-D-A-E-I-R-L-A-S-I-I-E-S-F-I-E-L-G-V-S-V-Y-D-F-P-G-T-Q-E-S-T-Q-G-M-V-T-N-L-K-R-N-V-E-R-I-K-L-L-N-Q-H-A-N-D-P-D-S-Q-L-R-N-M-N-I-P-L-E-V-L-Q-Y-I-E-D-G-R-N-P-D-V-Y-T-R-E-F-V-E-A-I-R-R-S-N-Q-Y-Q-R-A-K-M-H-A-L-K-K-L-R-D-S-L-A-E-K-I-G-E-E-F-P-D-L-V-P-Q-V-Q-G-I-I-E-R-A-N-G-S-R-D-K"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-P-Q-P-D-S-V-K-A-R-L-A-A-L-D-R-I-D-D-E-L-C-A-V-L-Q-H-A-Q-A-T-I-G-A-L-A-E-L-K-R-G-H-A-A-L-Q-P-Q-L-E-Q-H-V-R-D-Y-Y-R-T-L-E-H-S-T-V-A-L-R-N-E-I-R-E-L-D-A-A-V-G-T-Q-L-L-P-V-N-I-G-K-R-A-V-G-Q-D-Q-E-K-L-S-E-Q-L-A-Q-M-D-K-Y-V-G-S-M"} +{"text": "### FUNCTION Involved in ribosome biogenesis Required for normal pre-rRNA processing in internal transcribed spacer 1 ### SEQUENCE -M-V-A-K-K-R-T-Q-L-R-A-K-A-M-R-Q-R-R-N-S-S-E-A-M-E-T-E-E-L-P-P-D-P-K-A-F-L-H-Q-L-R-E-S-K-R-E-K-Q-L-N-R-S-Q-S-F-L-N-R-L-R-D-Q-A-G-N-G-G-I-S-K-S-A-L-R-R-R-K-K-R-M-K-E-E-L-K-P-R-M-E-D-L-L-T-S-L-K-E-E-G-V-L-E-E-D-E-S-G-E-L-A-A-V-T-G-V-T-A-I-T-A-S-N-G-Y-S-G-L-H-D-T-A-E-A-C-G-T-V-R-I-R-K-N-E-P-S-I-R-T-Q-R-G-A-K-L-L-T-T-K-E-Q-E-R-F-T-K-V-I-S-N-E-R-F-R-S-S-P-F-E-T-L-R-E-I-I-K-S-R-K"} +{"text": "### FUNCTION Involved in pre-mRNA splicing ### SEQUENCE -M-A-D-D-V-I-D-W-L-P-Y-V-D-T-L-D-Q-R-Y-L-N-E-V-E-K-T-V-T-A-E-L-A-A-I-E-Q-Q-E-L-H-P-R-I-A-E-L-F-P-A-V-R-H-H-W-D-E-Q-Y-G-L-Y-K-D-N-V-V-G-L-E-G-S-N-K-R-A-A-E-D-G-V-L-S-E-L-K-R-R-C-P-G-I-D-I-S-V-Y-N-D-D-S-E-D-P-V-L-L-A-T-I-A-G-Y-R-Y-H-Q-D-L-V-V-T-Q-L-L-P-Q-T-L-E-N-Q-W-A-I-N-N-A-Y-L-E-G-A-E-A-A-V-R-R-Q-L-Q-E-Q-E-Q-Q-I-A-Q-L-D-R-H-R-Q-E-L-Q-Q-R-E-A-L-R-F-R-Y-L-E-R-Q-W-R-D-R-L-H-G-N-L-E-R-A-A-G-N-I"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-S-A-K-A-Q-N-P-M-R-E-L-K-I-E-K-L-V-L-N-I-S-V-G-E-S-G-D-R-L-T-R-A-S-K-V-L-E-Q-L-S-G-Q-T-P-V-H-S-K-A-R-Y-T-V-R-T-F-G-I-R-R-N-E-K-I-A-V-H-V-T-I-R-G-P-K-S-E-E-I-L-E-R-G-L-K-V-K-E-Y-Q-L-R-T-K-N-F-S-E-T-G-N-F-G-F-G-I-Q-E-H-I-D-L-G-I-K-Y-D-P-S-I-G-I-Y-G-M-D-F-Y-V-V-M-G-R-P-G-G-R-V-S-R-R-K-R-C-R-S-T-V-G-N-S-H-K-T-S-K-E-D-T-I-A-W-F-K-Q-R-Y-D-A-D-V-L-D-K"} +{"text": "### FUNCTION Involved in peroxisome biogenesis ### SEQUENCE -M-V-S-K-A-S-R-D-Q-L-R-K-Y-G-A-V-S-L-A-S-L-L-V-A-A-S-I-V-A-Y-R-W-W-N-A-A-P-S-I-E-V-E-K-K-L-R-R-S-V-S-R-C-V-V-V-T-Q-G-I-Q-N-E-D-M-I-H-D-L-L-F-E-D-T-V-M-L-L-A-P-G-C-T-A-E-G-R-L-K-S-A-S-R-E-N-A-Y-K-V-I-S-C-T-T-W-Q-S-V-W-A-C-V-R-H-F-R-K-H-T-L-L-V-R-T-S-E-V-P-S-G-V-P-A-D-I-G-G-Y-V-S-D-I-S-D-I"} +{"text": "### FUNCTION Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner ### SEQUENCE -M-L-A-R-G-I-L-R-P-A-L-A-R-A-E-L-G-R-A-F-S-C-S-A-Q-W-Q-Q-A-A-G-S-T-S-G-R-E-L-S-W-P-D-F-F-A-L-R-K-T-E-R-R-I-N-T-G-S-S-V-L-T-A-F-L-T-A-N-C-A-W-A-Y-I-S-T-V-Q-I-D-V-T-Q-M-L-F-G-F-D-P-M-V-V-L-V-G-A-L-F-A-S-S-G-L-G-Y-L-C-G-P-L-M-G-S-A-F-F-R-V-K-H-R-G-Q-L-E-G-Y-N-H-K-N-R-V-F-L-E-H-I-K-K-N-R-V-D-A-S-S-Q-S-F-S-N-P-L-P-D-Y-Y-G-E-K-I-G-S-L-Q-E-Y-R-Q-W-L-R-D-C-Q-S-H-R-R-K-A-K-E-F-L"} +{"text": "### FUNCTION Involved in spore wall assembly ### SEQUENCE -M-S-L-W-S-F-A-V-F-W-F-Y-L-A-S-F-F-V-V-G-T-L-A-A-V-L-V-L-P-F-M-A-A-S-L-L-F-A-T-G-V-V-I-C-G-F-F-S-N-L-S-F-R-S-A-Q-L-V-Y-D-Q-F-V-G-T-L-Q-L-T-L-Q-H-M-A-E-Q-V-P-P-A-S-D-M-Q-Q-P-S-G-S-T-I-D-T-G-A-M-L-A-H-T-F-D-S-S-S-Y-G-A-T-T-Q-T-G-S-G-P-E-S-G-P-V-P-E-L-G-S-E-V-S-A-S-P-S-P-E-L-A-A-L-P-V-A-H-K-R-S-G-R-R-T-G-T-L-A-S-G-M"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-F-G-L-G-G-Q-P-Q-L-S-S-Q-Q-K-I-A-A-A-E-A-E-L-D-L-V-T-D-M-F-N-K-L-V-S-N-C-H-R-K-C-I-D-M-N-Y-N-E-G-D-L-N-K-N-E-S-N-C-L-D-R-C-V-A-K-Y-F-E-T-N-V-K-V-G-E-N-M-Q-Q-L-G-Q-N-F-S-P-G-K-F"} +{"text": "### FUNCTION Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body ### SEQUENCE -M-S-V-S-Y-N-G-G-L-T-G-L-T-A-L-V-R-N-N-L-V-H-Y-Q-Q-W-S-D-V-E-V-V-P-L-R-D-R-E-A-L-R-G-R-P-A-Q-K-L-S-N-D-D-E-E-I-G-V-E-Y-V-L-P-V-E-L-S-Q-Y-R-S-S-G-V-T-L-E-A-L-D-K-V-F-S-Q-L-P-A-S-C-K-R-V-V-L-A-I-S-S-D-D-G-T-V-V-Y-Y-T-V-Y-Q-G-L-Q-R-P-R-K-N"} +{"text": "### FUNCTION GTP-binding protein involved in protein trafficking ### SEQUENCE -M-G-V-S-F-S-K-L-F-S-N-L-F-G-H-K-E-M-R-I-L-M-V-G-L-D-G-A-G-K-T-T-V-L-Y-K-L-K-L-G-E-V-V-T-T-I-P-T-I-G-F-N-V-E-T-V-E-Y-K-N-I-S-F-T-V-W-D-V-G-G-Q-D-K-I-R-P-L-W-R-H-Y-F-R-N-T-E-G-I-I-F-V-V-D-S-N-D-R-S-R-I-A-E-A-R-E-V-L-Q-R-M-L-N-E-D-E-I-R-N-A-V-L-L-V-F-A-N-K-Q-D-L-P-E-A-M-S-A-A-E-I-T-E-K-L-G-L-H-S-I-R-Q-R-P-W-Y-I-Q-A-T-C-A-T-S-G-E-G-L-Y-E-G-L-E-W-L-S-T-N-L-K-N-Q-A"} +{"text": "### FUNCTION Facilitates protein transport into the nucleus Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import ### SEQUENCE -M-S-M-D-F-S-A-L-A-Q-Q-F-T-E-F-Y-Y-N-Q-F-D-T-D-R-S-Q-L-G-N-L-Y-R-D-Q-S-M-L-T-F-E-T-S-Q-L-Q-G-A-K-D-I-V-E-K-L-V-S-L-P-F-Q-K-V-Q-H-R-I-T-T-L-D-A-Q-P-A-S-P-N-G-D-V-L-V-M-I-T-G-D-L-L-I-D-D-E-Q-N-A-Q-R-F-S-Q-V-F-H-L-M-P-E-G-N-S-Y-Y-V-F-N-D-I-F-R-L-N-Y-S-A"} +{"text": "### FUNCTION Involved in translation ### SEQUENCE -M-F-K-K-F-S-K-E-D-I-H-T-R-T-K-V-K-T-S-V-Q-R-S-L-K-S-K-L-V-E-Q-F-P-K-L-E-E-V-I-D-E-L-L-P-K-K-T-E-L-Q-I-I-K-C-S-D-K-I-Q-L-Y-A-V-G-D-E-V-L-F-F-Q-K-F-E-E-L-I-P-T-L-R-F-V-H-K-Y-P-E-A-F-P-T-I-Q-I-D-R-G-A-I-K-F-V-L-S-G-A-N-I-M-C-P-G-L-T-S-S-G-A-A-L-P-E-A-P-G-L-A-Q-D-S-I-V-V-V-N-A-E-N-K-E-N-A-L-A-I-G-K-L-L-M-S-T-E-D-I-K-S-I-N-K-G-H-G-V-E-T-I-H-H-L-G-D-C-L-W-N-F-S-L-V"} +{"text": "### FUNCTION Required for the assembly of mitochondrial cytochrome c oxidase ### SEQUENCE -M-S-G-N-P-G-S-A-L-Q-A-L-S-P-T-P-P-E-R-G-S-F-P-L-D-H-E-G-E-C-T-A-Q-M-M-E-Y-L-N-C-M-K-L-V-R-G-E-N-A-P-N-C-R-L-L-A-R-N-Y-L-K-C-R-M-D-H-R-L-M-D-R-D-E-W-A-H-L-G-L-P-D-D-K-R-A-E-A-A-A-S-A-D-S-A-R-P-P-R-Q"} +{"text": "### FUNCTION Has a role in mitochondrial fission Has a role in outer membrane fission but not matrix separation ### SEQUENCE -M-S-N-I-N-F-L-P-T-I-E-D-A-Y-G-A-L-S-A-E-Q-L-D-I-L-R-Q-Q-V-L-S-E-G-G-D-I-A-S-I-Q-S-R-F-N-Y-A-W-G-L-V-K-S-H-D-A-E-D-Q-R-L-G-V-K-L-L-T-D-I-Y-K-E-S-P-M-R-R-R-E-S-L-Y-Y-L-A-I-G-C-Y-K-L-G-E-Y-A-M-A-K-R-Y-A-D-A-L-V-A-H-E-P-D-N-A-Q-A-R-T-L-K-A-M-V-E-Q-K-I-Q-T-E-G-L-K-G-A-A-L-V-G-A-G-L-A-A-V-A-A-A-A-G-F-L-L-R-Q-R-R-P"} +{"text": "### FUNCTION Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions ### SEQUENCE -M-T-K-K-D-K-K-Q-K-V-K-V-K-T-V-E-T-K-E-G-E-K-I-R-V-F-E-D-L-D-S-F-E-T-Y-L-R-G-E-T-E-D-E-E-F-D-H-V-H-C-Q-V-R-Y-Y-P-P-F-V-L-H-E-S-H-Q-D-P-E-K-I-K-E-S-A-N-S-H-N-K-K-F-V-R-H-L-H-Q-H-V-E-K-H-L-L-K-D-I-K-D-S-L-G-V-P-E-L-K-F-K-D-K-S-K-E-E-N-F-N-H-V-V-W-R-Y-H-A-P-T-A-V-R-D-R-E-F-L-V-H-V-T-V-E-C-H-N-D-T-A-M-V-D-V-D-Y-L-T-E-P-M-Q-P-A-V-Q-S-E-Q-V-A"} +{"text": "### FUNCTION Involved in pre-mRNA splicing ### SEQUENCE -M-D-L-N-L-L-K-S-W-N-P-Q-L-Q-K-N-R-K-K-V-Y-E-A-Q-Q-E-L-L-K-S-A-R-K-P-A-D-D-G-T-S-G-G-G-L-D-W-M-Y-E-G-Q-P-A-P-Q-R-K-V-R-K-R-R-T-R-T-R-K-P-K-Q-V-P-K-D-A-Q-G-K-L-Q-E-S-L-Q-T-A-R-S-D-A-P-E-G-T-C-S-P-D-E-T-A-A-A-R-G-G-Q-Q-G-A-P-V-E-V-S-A-K-S-P-A-K-A-V-A-E-A-R-G-G-P-G-S-S-G-V-H-G-E"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-S-D-S-N-N-I-S-S-L-Y-P-P-P-P-P-Y-V-K-F-F-T-K-D-N-L-E-R-L-A-E-Y-Q-S-S-H-V-T-T-D-P-E-Q-I-T-C-E-L-D-F-L-I-P-P-P-V-P-S-A-G-H-Y-R-A-F-G-S-V-W-Q-V-K-D-E-L-P-D-L-E-T-V-G-L-R-N-L-Y-D-D-R-G-Q-H-G-N-N-Y-Q-Y-K-I-K-E-L-H-K-L-L-K-S-L-L-L-N-M-L-E-L-V-S-V-L-S-V-N-P-E-R-F-P-D-K-V-E-H-I-R-T-I-L-F-N-I-H-H-L-L-N-E-Y-R-P-H-Q-S-R-E-S-L-I-M-L-L-E-E-Q-L-E-H-K-K-E-E-I-A-N-I-H-A-I-C-D-K-V-Q-A-K-L-A-A-M-C-K-Q-Y-I-A-D-D"} +{"text": "### FUNCTION DNA-binding protein that induces severe bending of DNA Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex ### SEQUENCE -M-A-A-A-A-T-T-K-K-R-T-Q-R-K-K-K-D-P-N-A-P-K-R-A-M-S-A-Y-M-F-F-A-N-E-N-R-D-I-V-R-A-E-N-P-G-I-S-F-G-Q-V-G-R-V-L-G-E-K-W-K-A-L-S-D-D-E-K-Q-P-Y-E-A-K-A-E-A-D-K-K-R-Y-E-S-E-K-E-L-Y-N-A-T-K-A-A"} +{"text": "### FUNCTION Essential role in pre-mRNA splicing Also essential for entry into mitosis ### SEQUENCE -M-G-S-V-F-L-P-H-L-H-S-G-W-H-V-D-Q-A-I-V-T-E-E-E-R-L-V-V-I-R-F-G-S-D-S-D-R-S-C-M-L-M-D-E-I-L-Y-S-I-A-E-K-V-V-N-F-A-A-I-Y-V-C-D-T-T-E-V-P-D-F-N-E-M-Y-E-L-Q-D-P-M-T-V-M-F-F-Y-K-N-K-H-M-R-C-D-F-G-T-G-N-N-N-K-M-N-F-V-V-D-N-K-Q-E-M-I-D-I-I-E-T-V-F-R-G-A-R-R-N-K-G-L-V-V-S-P-Y-D-Y-N-Y-K-R-I-Q"} +{"text": "### FUNCTION Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits Has a physiological role leading to 18S rRNA stability ### SEQUENCE -M-E-N-D-K-G-Q-L-V-E-L-Y-V-P-R-K-C-S-A-T-N-R-I-I-K-A-K-D-H-G-S-V-Q-I-N-I-A-Q-V-D-E-N-G-H-A-V-P-G-E-Y-I-T-Y-A-L-S-G-Y-V-R-A-R-G-E-A-D-D-S-M-N-R-L-A-Q-K-D-G-L-L-K-N-V-W-S-Y-S-R"} +{"text": "### FUNCTION Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A The NuA4 complex is also involved in DNA repair ### SEQUENCE -M-E-K-Q-R-K-E-Y-E-E-L-K-Q-K-L-K-Q-A-L-H-E-K-K-V-Q-E-Q-E-W-D-Q-I-Q-Q-E-I-F-D-K-E-T-E-Y-L-S-G-N-A-S-S-K-Y-G-T-I-V-K-G-F-D-G-F-G-K-H-A-S-Q-D-S-H-H-F-Q-D-Q-D-R-I-F-S-L-S-S-A-L-F-V-K-Q-Q-E-G-V-Q-D-E-E"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of mitochondrial acyl-carrier-protein ### SEQUENCE -M-L-V-P-H-D-R-M-V-G-N-K-R-R-G-T-M-R-V-L-G-I-G-T-D-L-V-Y-M-P-R-V-V-E-L-L-R-R-M-P-A-G-S-G-A-H-A-R-F-A-G-K-F-M-H-A-R-E-R-A-G-A-L-G-A-K-D-Q-A-R-Y-V-A-G-V-W-A-A-K-E-A-L-Y-K-A-V-A-G-A-D-A-P-P-A-A-T-L-Y-R-A-C-Y-K-E-A-D-A-V-G-R-P-T-L-Q-V-D-A-G-E-L-Q-R-A-G-H-M-R-F-W-E-E-R-L-A-G-T-R-F-L-L-S-V-S-H-D-E-D-Y-L-V-A-F-V-C-H-V-A-D-E-T-F-R-A-P-D-E-R-Q-R-I-T-K-N-S"} +{"text": "### FUNCTION Plays a role in the regulation of membrane potential Could mediate a proton leak ### SEQUENCE -M-N-S-T-K-V-V-N-V-I-I-A-I-F-L-P-P-V-A-V-F-L-A-R-G-W-G-V-E-C-I-V-D-L-L-L-T-I-F-F-F-F-P-G-M-L-Y-A-L-Y-I-V-L-T-S"} +{"text": "### FUNCTION E2-like enzyme required for the cytoplasm to vacuole transport ### SEQUENCE -M-L-S-A-E-D-F-S-D-Q-V-L-R-L-L-P-L-L-R-R-W-R-R-C-E-H-A-L-W-D-P-R-A-R-R-L-Q-L-S-V-A-T-A-R-N-S-A-R-F-D-V-R-V-D-L-H-P-L-Y-A-V-P-Q-L-L-L-R-Y-W-E-P-D-P-A-V-S-E-Y-E-V-W-K-L-H-F-V-D-P-Y-Q-L-P-L-W-Q-P-G-R-F-S-I-A-L-D-Q-V-P-A-T-S-G-S-A-Y-E-T-W-Y-V-V-N-S-C-D-T-D-A-N-V-G-P-E-T-D-N-Y-M-L-R-W-F-S-L-Y-G-Q-L-L-D-E-N-L-G-F-T-L-A-A-A-L-V-A-P-C-T-D-Q-K-K-A"} +{"text": "### FUNCTION Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes ### SEQUENCE -M-P-H-I-Q-F-L-P-P-E-P-V-V-L-V-S-R-V-A-D-D-P-D-P-A-G-P-G-L-H-V-A-K-V-A-V-G-D-C-T-I-V-D-A-R-T-P-C-A-P-L-Q-G-R-F-A-V-W-T-V-A-L-Q-L-H-S-P-D-T-P-R-S-L-T-L-R-K-R-Y-S-D-F-V-R-F-R-E-R-L-L-L-C-L-P-P-P-L-R-R-A-V-P-P-L-P-P-P-V-P-W-Y-D-A-W-R-Y-S-D-V-N-L-D-R-A-W-L-A-A-R-R-A-G-L-E-R-F-L-Q-Q-V-L-L-N-R-A-L-V-A-A-A-P-V-V-V-R-G-F-L-E-P-P-A-A-H-R-W-V-P-V-R-A"} +{"text": "### FUNCTION Inhibitor of the DOA4 deubiquitinase involved in the regulation of protein degradation by the proteasome and maintenance of a normal level of free ubiquitin ### SEQUENCE -M-K-S-S-A-Q-L-C-M-E-A-R-N-Y-N-F-N-A-A-A-P-L-R-L-Y-L-A-T-C-V-R-L-V-E-E-A-Q-A-A-A-Q-A-D-D-V-A-R-A-Y-M-L-Y-V-R-Y-L-D-L-C-M-H-Q-L-S-G-H-R-E-V-Q-Q-P-V-T-D-A-E-R-L-S-R-D-E-Y-E-Q-L-L-R-L-E-V-P-A-V-L-R-L-T-E-E-L-K-S-A-V-D-L-R-H-E-R-G-R-A-S-L-A-R-S-V-V-P-E-A-G-R-G-E-H-S-R-Q-E-V-Q-L-P-P-S-F-D-E-E-R-F-N-R-T-V-Q-W-F-L-A-A-G-R-S-M-S-L-P-V-S-A-E-E-P-A-V-R-E-V-F-S-Y-P-E-L-P-K-L-S-M-A-A-E-S-W-A-P-S"} +{"text": "### FUNCTION Involved in the processing of the 20S pre-rRNA ### SEQUENCE -M-V-G-V-G-K-K-F-T-K-E-S-K-V-R-E-I-Q-K-N-L-H-K-R-A-K-L-K-R-Q-Y-L-K-T-L-E-Q-E-G-Y-E-V-P-E-E-Q-K-R-Q-K-P-S-F-E-Q-R-K-G-E-K-K-Q-K-V-D-E-K-K-E-H-A-R-R-R-K-R-E-Q-K-E-E-M-E-A-K-R-Q-R-E-L-D-E-L-E-R-A-K-V-R-Q-V-E-R-E-R-R-N-K-R-I-Q-Q-K-T-R-S-G-Q-P-K-M-G-P-R-I-N-D-L-L-D-K-I-Q-K-D-T-T-Y-T-S"} +{"text": "### FUNCTION Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 ### SEQUENCE -M-L-T-T-T-I-P-Q-F-P-D-T-K-L-Y-I-S-L-F-R-N-V-S-N-A-P-E-I-V-D-S-L-A-E-L-P-Y-S-I-I-D-A-R-T-L-L-S-R-E-Q-L-L-S-A-V-Y-R-A-M-L-E-K-H-C-N-K-L-R-T-R-N-L-H-T-E-V-L-L-C-L-S-P-T-S-N-V-M-S-Q-I-G-D-A-M-K-R-F-G-I-K-K-D-S-T-S-V-V-L-V-K-A-V-T-G-D-E-T-F-D-P-K-G-F-S-E-V-I-R-G-E-E-L-E-F-S-D-T-A-L-R-E-S-A-D-I-D-T-I-R-E-N-Y-K-L-K-C-F-E-C-E-R-L-E-E-L-S-A-A-L-V-H-A-I-Q-L-R-G-L"} +{"text": "### FUNCTION Involved in the assembly of the cytochrome c oxidase complex ### SEQUENCE -M-A-W-W-P-F-S-R-N-N-K-P-G-V-P-E-Q-D-Q-V-A-A-A-P-V-Q-Q-R-P-A-E-P-L-P-T-N-Y-T-P-G-Q-R-L-L-L-E-D-T-R-P-R-F-D-T-Q-S-S-A-S-Q-Q-A-V-Q-R-E-R-A-T-L-A-D-A-W-K-T-V-R-W-E-D-F-S-L-E-R-M-A-G-I-P-C-F-R-D-A-G-M-A-G-F-S-A-M-V-V-A-G-S-V-T-F-L-F-H-K-N-P-V-R-A-A-N-W-G-V-G-G-L-L-L-G-S-I-V-G-W-E-Q-C-R-M-Q-R-R-R-S-F-Q-V-A-E-M-A-R-Q-T-V-A-A-K-E-A-P-M-L-R-K-P-D-N-A-Q-K-A-G-A-V-S-Q-A-S-E-L-P-P-K-K-P-W-Y-R-F-W"} +{"text": "### FUNCTION Probable component of the GPI-GlcNAc transferase complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI-anchors for cell surface proteins ### SEQUENCE -M-N-D-K-V-A-A-T-L-V-L-V-V-T-Y-S-I-V-G-A-S-L-W-C-L-T-Y-A-W-H-D-E-T-K-L-Y-Y-W-C-I-V-Q-L-L-P-V-M-L-W-V-W-C-V-I-S-W-C-G-A-Q-L-F-G-Y-A-K-R-G-K-A-D"} +{"text": "### FUNCTION Component of the INA complex -domain ### SEQUENCE -M-I-R-Y-A-L-L-R-S-G-R-R-T-L-Q-T-R-P-S-P-Q-T-L-E-E-L-A-R-L-K-S-L-E-D-V-D-S-S-V-I-R-K-L-I-N-Q-R-T-E-E-V-N-A-Q-N-E-A-Q-M-L-K-K-L-S-A-E-G-R-D-L-Q-N-V-P-G-S-R-Y-A-R-P-L-W-L-L-L-I-G-C-A-S-V-Y-L-V-R-D-W-L-R-M-K-A-E-Y-D-A-R-E-T-T-L-E-T-R-V-E-G-L-E-A-E-L-K-Y-L-L-E-P-K-P-G-V-L-E-V-E-V-V-Q-T-E-V-A-S-S-A-P-W-Y-K-R-W-L-W-S-G-S-R"} +{"text": "### FUNCTION Required for the assembly of cytochrome c oxidase ### SEQUENCE -M-P-V-D-T-A-A-P-Q-S-T-A-N-P-D-P-S-V-Q-T-D-R-A-A-V-N-F-T-P-S-T-D-A-S-S-F-Q-F-Y-P-D-N-P-E-S-P-L-A-R-Y-R-F-A-A-K-G-P-S-Q-Y-F-D-P-C-Q-E-S-A-N-M-S-M-K-C-L-E-R-N-N-Y-D-R-D-L-C-R-E-Y-F-D-A-Y-R-E-C-K-K-Q-W-L-S-A-R-R-K-D-N-S-Q-W-T"} +{"text": "### FUNCTION Component of the biogenesis of lysosome-related organelles complex-1 involved in endosomal cargo sorting ### SEQUENCE -M-N-E-K-Q-L-R-Q-Q-L-D-R-C-L-D-H-V-Q-E-H-V-D-M-L-S-A-R-A-I-S-K-L-S-G-D-A-V-A-N-H-E-W-L-S-E-L-S-G-R-Y-P-T-R-S-A-E-E-L-Q-Q-F-R-E-L-K-D-G-Y-V-K-K-L-D-T-L-E-T-E-V-K-Y-L-E-D-L-G-Q-E-L-A-E-F-Q-N-E-L-S-V-K-L-Q-R-I-R-R-N-S-Y-V-Q-E-N"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-S-G-I-S-P-T-E-L-Q-N-L-D-E-P-S-K-K-E-I-M-G-F-L-E-T-E-N-S-K-Q-K-V-Q-M-S-I-H-Q-F-T-N-L-C-F-K-N-C-I-H-S-V-Q-S-A-D-L-S-A-Q-E-N-Q-C-L-K-D-C-V-N-R-F-L-D-T-N-I-R-I-V-K-G-L-Q-S-I-Q"} +{"text": "### FUNCTION Required for the assembly of the V0 complex of the vacuolar ATPase in the endoplasmic reticulum ### SEQUENCE -M-A-V-D-V-P-T-S-V-I-V-K-L-M-F-F-T-L-A-M-V-S-F-P-V-L-T-F-F-V-S-Q-Q-Y-T-S-N-T-L-V-N-G-G-L-A-A-L-A-A-N-V-V-L-F-A-Y-V-I-M-A-F-S-E-D-V-P-Q-S-D-G-K-E-S-K-K-Q-Q"} +{"text": "### FUNCTION Allows the formation of correctly charged Gln-tRNA Required for proper protein synthesis within the mitochondrion ### SEQUENCE -M-P-L-A-R-L-V-E-G-E-K-H-D-E-C-T-Y-V-A-A-S-S-L-L-I-G-R-H-K-M-L-R-S-L-I-Y-A-S-R-R-W-S-S-S-V-G-A-R-F-S-S-R-E-E-L-Q-A-Y-L-A-R-P-A-W-Q-P-E-D-Y-L-P-S-A-E-D-I-A-R-Q-Q-L-S-E-E-E-T-R-K-L-L-K-L-S-G-L-P-E-A-D-I-Q-E-V-R-R-R-L-A-T-Q-L-S-F-V-S-Q-L-Q-S-V-E-V-D-D-C-A-D-P-Q-Y-A-K-A-M-Q-R-H-P-A-A-I-G-Y-E-E-L-V-R-R-A-E-L-D-A-K-D-T-S-L-G-E-K-S-G-S-W-D-S-T-A-T-A-T-L-K-K-D-G-Y-F-V-L-R-E-G-L-L-Q-K-R"} +{"text": "### FUNCTION Subunit of the V0 complex of vacuolar ### SEQUENCE -M-S-F-Y-T-V-V-A-T-F-L-S-V-V-L-A-S-A-V-F-W-V-L-A-P-K-E-N-Q-T-V-W-R-S-T-I-I-L-S-M-S-M-M-F-L-M-W-A-V-T-Y-L-S-Q-L-H-P-L-V-V-P-R-R-S-D-L-R-P-E-F-A-E"} +{"text": "### FUNCTION Involved in telomere length regulation and promotes fully efficient non-homologous end-joining by a mechanism activated in postdiauxic/stationary phase ### SEQUENCE -M-D-P-L-D-V-E-D-E-V-D-E-S-D-T-T-S-L-Q-A-Q-L-R-Q-N-A-I-R-K-Q-E-Q-F-Q-Q-E-I-Q-E-R-N-S-M-V-N-R-M-S-A-E-A-L-Q-Y-F-N-Q-L-H-K-A-E-C-S-K-K-E-E-L-Q-T-Y-I-D-E-N-L-K-V-F-E-K-K-Q-K-R-A-Q-A-P-T-K-N-N-E-R-S-S-S-T-H-A-A-L-E-E-H-K-A-A-S-V-T-K-K-K-L-G-I-V-K-K-G-A-P-R-K-T-K-I-R-L-P-V-R-K-S-P-N"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-T-D-R-L-T-Q-L-Q-Q-C-L-D-Q-I-V-E-Q-F-G-S-A-I-T-Y-V-D-R-N-H-D-F-E-P-H-N-E-L-E-D-K-L-S-D-P-Q-A-T-I-A-A-A-E-D-F-D-R-N-I-D-E-L-T-T-D-M-I-L-K-T-R-Q-I-I-K-L-I-D-S-L-P-G-V-D-V-S-A-E-E-Q-L-S-R-I-D-S-L-Q-K-K-L-I-Q-V-E-G-E-K-I-E-A-I-K-R-K-E-S-L-T-K-D-I-E-E-L-I-N-E-F-T-E-G-I-A-N-S-R-R-L-N-K-A"} +{"text": "### FUNCTION Involved in telomere length regulation ### SEQUENCE -M-L-Q-T-R-L-F-H-A-C-A-A-L-A-R-A-A-S-R-P-V-P-K-P-T-S-E-I-P-D-V-S-T-F-L-A-K-I-G-R-Q-C-S-E-H-A-E-L-Y-E-N-K-W-E-N-L-F-M-W-D-G-P-K-L-K-E-K-G-V-P-V-Q-Q-R-R-Y-I-L-Q-Q-V-E-R-L-R-Q-G-G-P-V-R-E-I-R-E-G-K-K-S-F-F-G-G-E-R-K-R-K-E-K-V-A-K-W-R-A-E-Q-R-H-A-A"} +{"text": "### FUNCTION Plays a role in autophagy Functions at the preautophagosomal structure ### SEQUENCE -M-N-S-K-N-T-I-V-Y-V-K-V-P-G-R-Q-R-E-G-F-V-D-P-P-P-F-E-W-N-Q-H-Q-D-R-K-L-W-A-H-I-S-T-I-E-D-K-D-D-I-D-W-Q-L-L-S-N-Q-T-N-A-P-E-F-F-I-R-K-R-V-Y-Q-L-F-R-V-H-L-K-S-I-E-Q-E-I-Y-S-H-T-S-A-D-R-A-P-N-R-S-S-Q-A-G-D-E-P-A-A-S-V-G-V-L-N-G-Y-G-Q-N-I-N-D-I-H-D-L-S-S-L-Q-T-P-P-T-C-R-G-K-A-N-K-D-E-D-G-G-N-S-S-G-I-S-E-L-S-S-L-S-V-S-K-S-A-L-E-E-A-L-M-D-R-L-Q-L"} +{"text": "### FUNCTION Essential for the assembly of ubiquinol-cytochrome c reductase It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b ### SEQUENCE -M-E-R-P-V-W-F-R-W-L-R-V-Y-A-I-G-F-G-I-I-G-A-G-V-L-L-F-K-Y-T-T-P-T-D-E-E-L-I-A-A-L-S-P-E-L-R-Q-Q-Y-E-R-E-R-K-L-R-Q-A-E-Q-Q-E-L-M-R-I-V-K-Q-T-A-A-S-E-T-P-V-W-N-T-G-P-I-K-S-P-W-E-R-K-G-V-S-A-E-S-R-E-Q-F-Q-Q-V-K-A-E-Q-V-Q-R-E-E-L-Q-R-I-R-E-E-L-E-T-I-R-Q-Q-S-A-N-K-T-Q-E-I-A-S-K-K-S-W-W-P-W"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-A-L-S-S-I-F-G-G-G-S-P-S-Q-Q-S-N-L-P-T-S-S-A-S-S-S-V-K-D-Q-L-K-G-Q-I-A-Q-E-L-A-V-A-N-A-T-E-L-V-N-K-V-T-E-N-C-F-E-K-C-L-M-A-P-Y-T-S-K-Q-D-T-C-V-D-Q-C-L-A-K-Y-M-R-S-W-N-A-I-S-Q-A-Y-V-A-R-I-Q-Q-A-S-A-N-G-D-I"} +{"text": "### FUNCTION Required for the assembly of the mitochondrial respiratory chain complex IV , also known as cytochrome c oxidase May participate in merging the COX1 and COX2 assembly lines ### SEQUENCE -M-S-L-G-S-R-T-F-R-S-K-R-Q-M-A-A-F-E-K-S-L-Q-G-R-Y-L-K-L-L-R-R-N-P-F-L-F-Y-G-V-P-F-C-T-L-M-A-V-G-S-Y-C-L-S-D-F-T-A-V-K-Y-E-R-E-D-K-K-V-R-S-V-Q-E-D-E-L-V-K-L-R-A-N-R-R-T-V-D-L-K-E-E-F-Y-R-L-Q-G-L-A-D-Q-D-W-E-P-V-R-V-P-R-L-P-G-E-S-E-N-V-W-D-V-E"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-S-I-V-K-S-K-I-R-T-I-P-D-Y-P-K-P-G-I-L-F-R-D-I-T-S-L-L-L-D-P-E-G-L-A-L-T-I-G-T-F-V-N-R-Y-Q-G-K-G-I-T-K-V-A-G-I-E-A-R-G-F-L-T-G-A-P-L-A-F-Q-L-G-V-G-F-I-P-I-R-K-K-G-K-L-P-S-E-T-V-S-E-E-Y-D-L-E-Y-G-K-D-V-I-E-V-H-K-D-S-I-Q-P-G-D-K-I-L-L-M-D-D-L-I-A-T-G-G-T-M-I-A-A-V-K-L-L-K-K-L-G-A-E-I-Y-E-A-G-V-I-I-D-L-P-D-L-G-G-R-K-K-L-Q-E-E-L-K-V-P-V-F-S-I-C-E-F-E-G-H"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-L-T-K-G-S-K-V-V-N-V-G-I-A-D-M-Q-G-A-Q-S-P-E-I-L-R-T-T-L-G-S-C-I-G-V-V-F-Y-A-P-D-K-K-I-G-A-M-A-H-F-M-L-S-K-D-P-S-G-K-D-S-Q-K-N-P-F-K-Y-A-E-T-A-I-P-L-L-I-K-K-M-N-E-M-G-C-N-P-G-E-Y-S-V-R-L-F-G-G-A-S-M-F-K-G-V-Q-S-S-F-L-Q-N-I-G-E-Q-N-I-L-T-A-R-A-I-L-E-Q-S-K-I-P-L-I-L-E-D-V-G-G-N-D-G-R-T-I-S-L-Y-L-D-D-G-R-V-L-L-K-K-G-G-F-E-K-Y-L-Y-K-V-R"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-D-F-E-K-V-K-S-I-I-V-E-Q-L-G-V-D-E-S-E-V-T-P-E-A-H-F-I-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-G-I-E-I-S-D-E-D-A-E-K-I-Q-T-V-G-D-V-T-K-F-I-D-N-L-K-S"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-P-Q-M-I-P-F-F-F-M-N-Q-L-T-Y-G-F-T-F-I-L-T-I-L-F-L-T-S-Y-V-F-L-P-M-I-L-R-L-Y-I-S-R-L-Y-I-S-K-L"} +{"text": "### FUNCTION Probable thiol-disulfide oxidoreductase that may be involved in the redox regulation of a number of cytosolic enzymes ### SEQUENCE -M-G-C-C-G-S-S-T-V-D-A-E-E-H-L-D-Y-S-G-G-N-V-T-L-V-T-D-Q-K-N-W-D-N-T-M-E-E-V-A-E-H-G-K-T-V-V-L-K-F-S-A-I-W-C-T-P-C-R-N-A-A-P-L-F-A-E-L-S-L-K-Y-P-D-I-V-F-V-S-V-D-V-D-E-M-P-E-L-V-T-Q-Y-D-V-R-A-T-P-T-F-I-F-M-K-N-N-E-E-I-D-K-L-V-G-G-N-H-E-D-L-Q-E-K-F-E-Q-L-N-R-P-K-L-Y-D-D-V"} +{"text": "### FUNCTION May serve as docking site to facilitate the association of other proteins to the plasma membrane ### SEQUENCE -M-S-G-G-V-Q-E-Q-F-E-I-K-F-R-L-P-D-G-T-D-I-G-P-K-R-Y-P-A-A-S-T-V-A-T-L-K-E-S-I-V-A-Q-W-P-K-D-K-E-K-G-P-R-T-V-N-D-L-K-L-I-N-A-G-K-I-L-E-N-N-K-T-L-S-E-C-K-S-P-I-C-D-F-S-G-L-T-T-M-H-V-V-V-R-A-P-T-S-D-K-Q-S-N-K-I-V-A-K-K-P-K-D-F-R-C-G-C-S-I-M"} +{"text": "### FUNCTION Tubulin-folding protein ### SEQUENCE -M-V-L-D-T-K-R-S-L-K-I-K-I-D-A-L-K-R-L-E-K-D-Y-M-L-Y-K-K-E-E-Q-L-Q-I-E-N-V-E-R-F-K-A-D-E-T-K-D-I-Y-D-V-K-K-Q-I-E-I-L-D-E-N-K-T-M-I-I-D-S-V-S-R-V-T-A-F-L-V-Q-F-S-E-F-L-E-E-H-K-N-E-D-D-G-S-E-I-W-K-D-S-Y-D-I-I-D-Q-I-S-T-K-F-L-G-E"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-A-G-Q-Y-W-R-A-A-G-I-T-Y-L-Q-Y-A-N-I-C-G-T-H-V-R-N-C-L-K-E-P-F-R-A-A-A-K-N-R-E-G-F-I-S-N-T-V-M-Y-Q-N-G-K-E-S-S-T-I-I-L-N-S-E-L-L-Q-K-E-L-L-V-K-K-N"} +{"text": "### FUNCTION Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes May directly activate some type-A response regulators in response to cytokinins ### SEQUENCE -M-A-R-K-M-I-R-V-L-L-V-E-D-E-E-I-N-R-V-V-A-R-A-A-L-K-A-A-G-G-G-D-V-V-D-E-A-E-N-G-E-V-A-V-Q-R-V-R-D-A-A-A-P-Y-D-L-V-L-M-D-K-Q-M-P-V-M-D-G-H-E-A-T-R-R-I-R-G-M-G-V-T-T-P-I-V-A-V-S-S-D-G-L-P-A-D-V-D-A-F-I-T-A-G-A-D-D-F-T-S-K-P-L-S-K-E-K-L-G-V-I-L-A-K-F-R-L-A"} +{"text": "### FUNCTION Beta-2 bungarotoxin is a presynaptic neurotoxin of the venom The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and is non-toxic ### SEQUENCE -S-S-G-G-L-L-L-L-L-G-L-L-T-L-C-A-E-L-I-P-V-S-S-R-Q-R-H-R-D-C-D-K-P-P-D-K-G-N-C-G-S-V-R-R-A-F-Y-Y-D-T-R-L-K-T-C-K-A-F-P-Y-R-G-C-N-G-N-G-N-H-F-K-T-E-T-L-C-R-C-E-C-L-V-Y-P"} +{"text": "### FUNCTION Beta-bungarotoxin is a presynaptic neurotoxin of the venom The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and is non-toxic ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-W-A-E-L-T-P-V-S-S-R-K-R-H-P-D-C-D-K-P-P-D-T-R-I-C-Q-T-V-V-R-A-F-Y-Y-K-P-S-E-K-R-C-V-Q-F-R-Y-G-G-C-K-G-N-G-N-H-F-K-S-D-H-L-C-R-C-E-C-L-E-Y-R"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-T-D-V-K-K-N-E-N-M-T-F-E-E-A-M-K-K-L-E-E-I-V-E-K-L-E-E-G-N-V-P-L-E-E-A-I-A-F-F-Q-E-G-M-K-L-S-K-L-C-H-D-K-L-Q-H-V-E-K-Q-L-E-Y-M-L-R-E-D-G-E-L-V-P-F-S-P-E-E-E"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-I-E-T-I-I-G-N-I-Q-T-L-P-S-L-P-P-H-I-E-R-V-Y-M-A-S-D-D-L-V-K-R-I-Q-R-V-V-T-D-H-G-R-E-L-G-I-R-L-K-E-A-K-E-L-A-D-G-D-V-L-W-M-D-D-H-N-A-I-V-V-S-V-L-P-E-D-L-L-V-I-K-P-V-S-L-K-Q-M-G-E-I-A-H-Q-I-G-N-R-H-L-P-A-Q-F-E-E-G-E-M-L-V-Q-Y-D-Y-L-V-E-E-L-L-Q-Q-L-A-I-P-Y-K-R-E-K-R-K-V-K-Q-A-F-R-H-I-G-H-R-H-D"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-K-I-Y-K-D-I-I-T-G-D-E-M-F-S-D-T-Y-K-M-K-L-V-D-E-V-I-Y-E-V-T-G-R-L-V-T-R-A-Q-G-D-I-Q-I-E-G-F-N-P-S-A-E-E-A-D-E-G-T-D-S-A-V-E-S-G-V-D-I-V-L-N-H-R-L-V-E-T-Y-A-F-G-D-K-K-S-Y-T-L-Y-L-K-D-Y-M-K-K-L-V-A-K-L-E-E-K-A-P-D-Q-V-E-V-F-K-T-N-M-N-K-V-M-K-D-I-L-G-R-F-K-E-L-Q-F-F-T-G-E-S-M-D-C-D-G-M-V-A-M-M-E-Y-R-D-F-D-G-T-Q-I-P-I-M-M-F-F-K-H-G-L-E-E-E-K-F"} +{"text": "### FUNCTION Inhibits voltage-gated sodium channels by binding to site 3 Insecticidal neurotoxin ### SEQUENCE -T-S-Q-G-T-T-P-D-K-V-Q-L-E-V-N-C-I-S-N-L-P-N-N-E-V-E-E-T-D-L-L-R-E-L-E-M-I-E-E-N-L-F-G-K-E-L-S-F-V-P-E-E-N-R-N-S-R-H-K-R-C-M-G-Y-D-I-E-C-N-E-R-L-H-C-C-A-D-L-E-C-V-K-T-S-G-R-W-W-Y-K-K-T-Y-C-R-R-K-S-G"} +{"text": "### FUNCTION RuBisCO catalyzes two reactions the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process Both reactions occur simultaneously and in competition at the same active site Although the small subunit is not catalytic it is essential for maximal activity ### SEQUENCE -M-R-V-T-Q-G-T-F-S-F-L-P-D-L-T-D-E-Q-I-N-K-Q-L-A-Y-I-V-S-K-G-F-S-A-N-V-E-Y-T-D-D-P-H-P-R-N-S-Y-W-E-L-W-G-L-P-L-F-D-V-K-D-A-S-A-V-M-Y-E-I-S-S-C-R-K-A-K-P-N-Y-Y-I-K-V-N-A-F-D-N-T-R-G-I-E-S-C-V-L-S-F-I-V-N-R-P-I-N-E-P-G-F-L-L-Q-R-Q-D-F-E-G-R-T-M-K-Y-S-L-H-S-Y-A-T-E-K-P-E-G-A-R-Y"} +{"text": "### FUNCTION RuBisCO catalyzes two reactions the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process Both reactions occur simultaneously and in competition at the same active site Although the small subunit is not catalytic it is essential for maximal activity ### SEQUENCE -M-R-L-T-Q-G-A-F-S-F-L-P-D-L-T-D-E-Q-I-N-K-Q-L-A-Y-I-V-S-K-G-L-S-A-N-V-E-Y-T-D-D-P-H-P-R-N-S-Y-W-E-L-W-G-L-P-L-F-D-V-K-D-A-S-A-V-M-Y-E-I-S-S-C-R-K-A-K-P-N-Y-Y-V-K-V-N-A-F-D-N-T-R-G-I-E-S-C-V-M-S-F-I-V-N-R-P-A-N-E-P-G-F-L-L-Q-R-Q-D-F-E-G-R-T-M-K-Y-S-L-H-S-Y-A-T-E-K-P-E-G-A-R-Y"} +{"text": "### FUNCTION RuBisCO catalyzes two reactions the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process Both reactions occur simultaneously and in competition at the same active site Although the small subunit is not catalytic it is essential for maximal activity ### SEQUENCE -M-R-L-T-Q-G-T-F-S-F-L-P-D-L-T-D-E-Q-I-S-K-Q-L-T-Y-I-V-S-K-G-L-S-A-N-V-E-Y-T-D-D-P-H-P-R-N-S-Y-W-E-L-W-G-L-P-L-F-D-V-K-D-A-S-A-V-M-Y-E-I-S-S-C-R-K-A-K-P-N-Y-Y-I-K-V-N-A-F-D-N-T-R-G-I-E-S-C-V-M-S-F-I-V-N-R-P-I-N-E-P-G-F-L-L-Q-R-Q-D-F-E-G-R-T-M-K-Y-S-L-H-S-Y-A-T-E-K-P-E-G-A-R-Y"} +{"text": "### FUNCTION RuBisCO catalyzes two reactions the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process Both reactions occur simultaneously and in competition at the same active site Although the small subunit is not catalytic it is essential for maximal activity ### SEQUENCE -M-R-L-T-Q-G-T-F-S-F-L-P-D-L-T-D-E-Q-I-N-K-Q-L-T-Y-I-V-S-K-G-L-S-A-N-V-E-Y-T-D-D-P-H-P-R-N-S-Y-W-E-L-W-G-L-P-L-F-D-V-K-D-A-S-A-V-M-Y-E-I-S-S-C-R-K-A-K-P-N-Y-Y-V-K-V-N-A-F-D-N-T-R-G-I-E-S-C-V-M-S-F-I-V-N-R-P-A-N-E-P-G-F-L-L-Q-R-Q-D-F-E-G-R-T-M-K-Y-S-L-H-S-Y-A-T-E-K-P-E-G-A-R-Y"} +{"text": "### FUNCTION RuBisCO catalyzes two reactions the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process Both reactions occur simultaneously and in competition at the same active site Although the small subunit is not catalytic it is essential for maximal activity ### SEQUENCE -M-R-L-T-Q-G-T-F-S-F-L-P-D-L-T-D-E-Q-I-N-K-Q-L-A-Y-I-V-S-K-G-L-S-A-N-V-E-Y-T-D-D-P-H-P-R-N-S-Y-W-E-L-W-G-L-P-L-F-D-V-K-D-A-S-A-V-M-Y-E-I-S-S-C-R-K-A-K-P-N-Y-Y-V-K-V-N-A-F-D-N-T-R-G-I-E-S-C-V-M-S-F-I-V-N-R-P-A-N-E-P-G-F-L-L-Q-R-Q-D-F-E-G-R-T-M-K-Y-S-L-H-S-Y-A-T-E-K-P-E-G-A-R-Y"} +{"text": "### FUNCTION May have antimicrobial activity ### SEQUENCE -M-M-F-T-Y-V-V-A-V-A-S-V-V-A-L-T-S-A-Y-P-T-G-A-P-P-S-A-C-F-D-M-I-P-G-H-A-A-D-V-Q-T-V-P-A-P-Y-T-I-T-T-A-V-S-S-V-K-A-G-H-S-I-D-V-V-I-S-G-K-T-P-E-D-K-M-A-G-I-L-L-E-A-R-Q-G-D-K-I-V-G-T-W-T-V-S-P-D-D-T-F-S-Q-P-L-N-C-G-E-P-N-N-A-V-T-H-K-M-H-A-K-E-L-D-R-Q-T-V-S-Y-P-W-T-A-P-K-D-L-E-G-D-V-V-F-K-V-T-I-V-K-S-Y-A-V-F-W-V-G-I-E-S-A-P-V-K-V-L-S-H"} +{"text": "### FUNCTION Escorts unspliced or incompletely spliced viral pre-mRNAs ### SEQUENCE -M-T-T-R-E-K-D-L-Q-K-G-L-R-L-L-H-L-L-H-Q-T-N-P-Y-P-Q-T-P-G-T-A-S-Q-R-R-N-R-R-R-R-W-K-R-R-G-L-Q-I-L-A-L-A-D-R-I-R-S-L-S-D-S-P-T-E-E-P-L-D-L-A-V-Q-R-L-Q-E-L-T-V-E-D-L-P-N-P-P-T-S-T-P-T-A-Q-A-F-T-C-I-P-P-V-W-D-Q-L-V-P-R-S-N-P-S-S-N-E-G-C-E-R-D-S-C-E-H-R-K-S-P-M-E-S-S-Q-K-D-S-G-S-N-H-R-D-P-Q-E-D-Q-T-R-T"} +{"text": "### FUNCTION Plays a role in nuclear translocation of the viral pre-integration complex ### SEQUENCE -M-D-P-R-E-R-V-P-P-G-N-S-D-E-E-T-I-G-E-A-F-D-W-L-E-R-T-I-T-E-L-N-R-V-A-V-N-H-L-P-R-E-L-I-F-Q-V-W-Q-R-C-W-A-Y-W-R-E-E-Q-G-M-S-S-S-Y-T-K-Y-R-Y-L-L-L-M-Q-K-A-M-F-V-H-Y-T-K-G-C-R-C-L-Q-E-G-H-G-P-G-G-W-R-S-G-P-P-P-P-P-P-P-G-L-A"} +{"text": "### FUNCTION Stimulates gene expression driven by the HIV-2 LTR Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle Cell cycle arrest creates a favorable environment for maximizing viral expression and production ### SEQUENCE -M-A-E-A-A-P-E-T-P-P-E-N-E-S-P-Q-R-E-P-W-E-E-W-V-E-D-V-M-E-E-I-K-Q-E-A-L-R-H-F-D-P-R-L-L-T-A-L-G-N-F-I-Y-S-R-H-G-D-T-L-A-G-A-G-E-L-I-K-I-L-Q-R-A-L-F-L-H-F-R-A-G-C-Q-H-S-R-I-G-Q-P-G-G-G-N-P-L-S-A-I-P-P-S"} +{"text": "### FUNCTION Effector component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane ### SEQUENCE -M-Q-F-G-A-D-T-E-F-S-N-M-C-G-V-T-L-M-N-T-P-I-G-R-V-V-A-D-V-M-G-A-K-D-G-V-E-L-T-E-Y-P-S-M-I-R-V-D-G-V-N-R-L-D-F-D-Y-D-E-L-T-D-A-L-G-Q-D-F-D-G-S-I-F-E-E-I-S-S-T-H-Y-G-R-M-V-H-L-D-D-K-T-I-L-F-A-S-P-E-D-A-A-E-F-I-G-F-D-L-T-A-S"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-V-T-D-L-R-P-G-T-K-V-K-M-D-G-G-L-W-E-C-V-E-Y-Q-H-Q-K-L-G-R-G-G-A-K-V-V-A-K-F-K-N-L-E-T-G-A-T-V-E-R-T-F-N-S-G-E-K-L-E-D-I-Y-V-E-T-R-E-L-Q-Y-L-Y-P-E-G-E-E-M-V-F-M-D-L-E-T-Y-E-Q-F-A-V-P-R-S-R-V-V-G-A-E-F-F-K-E-G-M-T-A-L-G-D-M-Y-E-G-Q-P-I-K-V-T-P-P-T-V-V-E-L-K-V-V-D-T-P-P-G-V-R-G-D-T-V-S-G-G-S-K-P-A-T-L-E-T-G-A-V-V-Q-V-P-L-F-V-E-P-G-E-V-I-K-V-D-T-R-T-G-E-Y-V-G-R-A"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-A-L-R-P-L-V-K-P-K-I-V-K-K-R-T-K-K-F-I-R-H-Q-S-D-R-Y-V-K-I-K-R-N-W-R-K-P-R-G-I-D-N-R-V-R-R-R-F-K-G-Q-I-L-M-P-N-I-G-Y-G-S-N-K-K-T-K-H-M-L-P-S-G-F-R-K-F-L-V-H-N-V-K-E-L-E-V-L-L-M-C-N-K-S-Y-C-A-E-I-A-H-N-V-S-S-K-N-R-K-A-I-V-E-R-A-A-Q-L-A-I-R-V-T-N-P-N-A-R-L-R-S-E-E-N-E"} +{"text": "### FUNCTION This is an intracellular thiol proteinase inhibitor Tightly binding reversible inhibitor of cathepsins L, H and B ### SEQUENCE -M-M-C-G-A-P-S-A-T-Q-P-A-T-A-E-T-Q-H-I-A-D-Q-V-R-S-Q-L-E-E-K-E-N-K-K-F-P-V-F-K-A-V-S-F-K-S-Q-V-V-A-G-T-N-Y-F-I-K-V-H-V-G-D-E-D-F-V-H-L-R-V-F-Q-S-L-P-H-E-N-K-P-L-T-L-S-N-Y-Q-T-N-K-A-K-H-D-E-L-T-Y-F"} +{"text": "### FUNCTION May be involved in the development and regeneration of the musculoskeletal system ### SEQUENCE -M-S-Q-P-D-P-V-K-K-K-R-P-P-V-K-E-E-D-L-K-G-A-R-G-N-L-S-K-N-Q-E-I-K-S-K-T-Y-Q-V-M-K-Q-C-E-Q-M-G-S-A-A-P-S-I-F-S-R-A-R-T-G-S-E-T-V-F-E-K-S-K-D-E-P-P-K-S-V-F-G"} +{"text": "### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-D-P-N-T-V-S-S-F-Q-D-I-L-L-R-M-S-K-M-Q-L-E-S-S-S-E-D-L-N-G-M-I-T-Q-F-E-S-L-K-L-Y-R-D-S-L-G-E-A-V-M-R-M-G-D-L-H-S-L-Q-N-R-N-E-K-W-R-E-Q-L-G-Q-K-F-E-E-I-R-W-L-I-E-E-V-R-H-K-L-K-I-T-E-N-S-F-E-Q-I-T-F-M-Q-A-L-H-L-L-L-E-V-E-Q-E-I-R-T-F-S-F-Q-L-I"} +{"text": "### FUNCTION Glutaredoxin necessary for virion morphogenesis and virus replication Functions as a thiol-disulfide transfer protein between membrane-associated OPG128 and substrates OPG095 or OPG053 The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves oxidation of OPG072, OPG128 and OPG088 Exhibit thioltransferase and dehydroascorbate reductase activities in vitro ### SEQUENCE -M-K-N-V-L-I-I-F-G-K-P-Y-C-S-I-C-E-N-V-S-E-A-V-E-E-L-K-S-E-Y-D-I-L-H-V-D-I-L-S-F-F-L-K-D-G-D-S-S-M-L-G-D-V-K-R-G-T-L-I-G-N-F-A-A-H-L-S-N-Y-I-V-S-I-F-K-Y-N-P-Q-T-K-Q-M-A-F-V-D-I-N-K-S-L-D-F-T-K-T-D-K-S-L-V-N-L-E-I-L-K-S-E-I-E-K-A-N-Y-G-V-W-P-P-V-T-E"} +{"text": "### FUNCTION Early protein involved in virion morphogenesis Participates in the formation and elongation of crescent-shaped membrane precursors of immature virions in cytoplasmic factories ### SEQUENCE -M-E-V-I-A-D-R-L-D-D-I-V-K-Q-N-I-A-D-E-K-F-V-D-F-V-I-H-G-L-E-H-Q-C-P-A-I-L-R-P-L-I-R-L-F-I-D-I-L-L-F-V-I-V-I-Y-I-F-T-V-R-L-V-S-R-N-Y-Q-M-L-L-A-L-V-A-L-V-I-T-L-T-I-F-Y-Y-F-I-L"} +{"text": "### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-D-S-N-T-V-S-S-F-Q-D-I-L-M-R-M-S-K-M-Q-L-G-S-S-S-E-D-L-N-G-M-I-T-Q-F-E-S-L-K-L-Y-R-D-S-L-G-E-A-V-M-R-M-G-D-L-H-S-L-Q-S-R-N-G-K-W-R-E-Q-L-S-Q-K-F-E-E-I-R-W-L-I-E-E-V-R-H-R-L-K-I-T-E-N-S-F-E-Q-I-T-F-M-Q-A-L-Q-L-L-L-E-V-E-Q-E-I-R-T-F-S-F-Q-L-I"} +{"text": "### FUNCTION May self assemble to form a helical capsid wrapping up the viral genomic DNA The virion assembly and budding take place at the host inner membrane ### SEQUENCE -M-I-K-L-V-L-L-V-A-A-I-A-I-F-G-T-G-F-I-T-V-I-I-N-Q-F-T-S-A-K-N-I-I-M-D-L-Y-N-S-D-T-W-L-I-W-L-F-G-R-M-A-V-L-F-S-H-P-L-M-L-T-I-S-S-L-Y-I-V-G-F-I-V-S-K-T-L-Y-S"} +{"text": "### FUNCTION Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry Also plays a role in cell-cell fusion ### SEQUENCE -M-T-D-E-Q-I-Y-A-F-C-D-A-N-K-D-D-I-R-C-K-C-I-Y-P-D-K-S-I-V-R-I-G-I-D-T-R-L-P-Y-Y-C-W-Y-E-P-C-K-R-S-D-A-L-L-P-A-S-L-K-K-N-I-T-K-C-N-V-S-D-C-T-I-S-L-G-N-V-S-I-T-D-S-K-L-D-V-N-N-V-C-D-S-K-R-V-A-T-E-N-I-A-V-R-Y-L-N-Q-E-I-R-Y-P-I-I-D-I-K-W-L-P-I-G-L-L-A-L-A-I-L-I-L-A-F-F"} +{"text": "### FUNCTION The protein is truncated in this strain and presumably inactive It has similarities with variola virus CrmB, but the product is inactivated due to several premature stop codons ### SEQUENCE -M-K-S-V-L-Y-S-Y-I-L-F-L-S-C-I-I-I-N-G-R-D-I-A-P-H-A-P-S-D-G-K-C-K-D-N-E-Y-K-R-H-N-L-C-P-G-T-Y-A-S-R-L-C-D-S-K-T-N-T-Q-C-T-P-C-G-S-G-T-F-T-S-R-N-N-H-L-P-A-C-L-S-C-N-G-R-R-D-R-V-T-R-L-T-I-E-S-V-N-A-L-P-D-I-I-V-F-S-K-D-H-P-D-A-R-H-V-F-P-K-Q-N-V-E"} +{"text": "### FUNCTION Participates in either intracellular transport of viral proteins or intercellular spread of the virus Cellular profilins modulate actin filament dynamics In contrast to cellular homologs, the poxvirus profilins seem to bind actin only weakly ### SEQUENCE -M-A-E-W-H-K-I-I-E-D-I-S-K-N-N-K-F-E-D-A-A-I-V-D-Y-K-T-T-K-N-V-L-A-A-I-P-N-R-T-F-A-K-I-N-P-G-E-I-I-P-L-I-T-N-R-N-I-L-K-P-L-I-G-Q-K-Y-C-I-V-Y-T-N-S-L-M-D-E-N-T-Y-A-M-E-L-L-T-G-Y-A-P-V-S-P-I-V-I-A-R-T-H-T-A-L-I-F-L-M-G-K-P-T-T-S-R-R-D-V-Y-R-T-C-R-D-H-A-T-R-V-R-A-T-G-N"} +{"text": "### FUNCTION Has thioltransferase and dehydroascorbate reductase activities ### SEQUENCE -M-A-E-E-F-V-Q-Q-R-L-A-N-N-K-V-T-I-F-V-K-Y-T-C-P-F-C-R-N-A-L-D-I-L-N-K-F-S-F-K-R-G-A-Y-E-I-V-D-I-K-E-F-K-P-E-N-E-L-R-D-Y-F-E-Q-I-T-G-G-R-T-V-P-R-I-F-F-G-K-T-S-I-G-G-Y-S-D-L-L-E-I-D-N-M-D-A-L-G-D-I-L-S-S-I-G-V-L-R-T-C"} +{"text": "### FUNCTION Virulence factor that affects the acute immune response to infection Bcl-2-like protein which, through its interaction with the DEAD box RNA helicase DDX3X/DDX3, prevents TBK1/IKKepsilon-mediated IRF3 activation Contributes to virulence by binding to the host TRAF6 and IRAK2 and preventing host NF-kappa-B activation ### SEQUENCE -M-A-T-K-L-D-Y-E-D-A-V-F-Y-F-V-D-D-D-K-I-C-S-R-D-S-I-I-D-L-I-D-E-Y-I-T-W-R-N-H-V-I-V-F-N-K-D-I-T-S-C-G-R-L-Y-K-E-L-M-K-F-D-D-V-A-I-R-Y-Y-G-I-D-K-I-N-E-I-V-E-A-M-S-E-G-D-H-Y-I-N-F-T-K-V-H-D-Q-E-S-L-F-A-T-I-G-I-C-A-K-I-T-E-H-W-G-Y-K-K-I-S-E-S-R-F-Q-S-L-G-N-I-T-D-L-M-T-D-D-N-I-N-I-L-I-L-F-L-E-K-K-L-N"} +{"text": "### FUNCTION Virion protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-N-L-I-I-H-R-Y-G-D-I-S-R-G-C-D-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-N-Q-R-L-A-C-G-V-I-G-I-S-Y-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V"} +{"text": "### FUNCTION Glutaredoxin necessary for virion morphogenesis and virus replication Functions as a thiol-disulfide transfer protein between membrane-associated OPG128 and substrates OPG095 or OPG053 The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves oxidation of OPG072, OPG128 and OPG088 Exhibit thioltransferase and dehydroascorbate reductase activities in vitro ### SEQUENCE -M-K-N-V-L-I-I-F-G-K-P-Y-C-S-I-C-E-N-V-S-E-A-V-E-E-L-K-S-E-Y-D-I-L-H-V-D-I-L-S-F-F-L-K-D-G-D-S-S-M-L-G-D-V-K-R-G-T-L-I-G-N-F-A-A-H-L-S-N-Y-I-V-S-I-F-K-Y-N-P-Q-T-K-Q-M-A-F-V-D-I-N-K-S-L-D-F-T-K-T-D-K-S-L-V-N-L-E-I-L-K-S-E-I-E-K-A-N-Y-G-V-W-P-P-V-T-E"} +{"text": "### FUNCTION Has thioltransferase and dehydroascorbate reductase activities ### SEQUENCE -M-A-E-E-F-V-Q-Q-R-L-A-N-N-K-V-T-I-F-V-K-F-T-C-P-F-C-R-N-A-L-D-I-L-N-K-F-S-F-K-R-G-A-Y-E-I-V-D-I-K-E-F-K-P-E-N-E-L-R-D-Y-F-E-Q-I-T-G-G-R-T-V-P-R-I-F-F-G-K-T-S-I-G-G-Y-S-D-M-L-E-I-D-N-M-D-A-L-G-D-I-L-S-S-I-G-V-L-R-T-C"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-F-N-M-N-I-N-S-P-V-R-F-V-K-E-T-N-R-A-K-S-P-T-R-Q-S-P-Y-A-A-G-Y-D-L-Y-S-A-Y-Y-Y-T-I-P-P-G-E-R-Q-L-I-K-T-D-I-S-M-S-M-P-K-F-C-Y-G-R-I-A-P-R-S-G-L-S-L-K-G-I-D-I-G-G-G-V-I-D-E-D-Y-R-G-N-I-G-V-I-L-I-N-N-G-K-C-T-F-N-V-N-T-G-D-R-I-A-Q-L-I-Y-Q-R-I-Y-Y-P-E-L-K-E-V-Q-S-L-D-S-T-D-R-G-D-Q-G-F-G-S-T-G-L-R"} +{"text": "### FUNCTION Stimulates cellular proliferation and mobility around infected cells to promote rapid and efficient spread of infection ### SEQUENCE -M-S-M-K-Y-L-M-L-L-F-A-T-M-I-I-R-S-F-A-D-S-G-N-A-I-E-T-T-S-P-E-I-T-N-T-T-T-D-I-P-A-I-R-L-C-G-P-E-G-D-G-Y-C-L-H-G-D-C-I-H-A-R-D-I-N-G-M-Y-C-R-C-S-H-G-Y-T-G-I-R-C-Q-H-V-V-L-V-D-Y-Q-R-S-E-K-P-N-T-T-T-S-Y-I-P-S-P-G-I-V-L-V-L-V-G-I-I-M-C-C-L-L-S-V-Y-R-F-T-R-R-T-N-K-L-P-L-Q-D-M-V-V-P"} +{"text": "### FUNCTION The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide in human intestinal microvilli ### SEQUENCE -M-K-K-T-L-L-I-A-A-S-L-S-F-F-S-A-S-A-L-A-T-P-D-C-V-T-G-K-V-E-Y-T-K-Y-N-D-D-D-T-F-T-V-K-V-G-D-K-E-L-F-T-N-R-W-N-L-Q-S-L-L-L-S-A-Q-I-T-G-M-T-V-T-I-K-T-N-A-C-H-N-G-G-G-F-S-E-V-I-F-R"} +{"text": "### FUNCTION Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing ### SEQUENCE -M-E-R-R-F-I-V-Y-Y-N-C-S-D-C-A-C-G-R-Y-V-S-S-L-L-T-M-S-G-A-Y-V-N-V-C-V-C-I-V-F-F-I-L-V-Y-L-S-S-C-Y-N-M-R-V-L-G-F-L-R-V-C-I-Y-L-Y-K-L-C-R"} +{"text": "### FUNCTION Virion protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-N-L-I-I-H-R-Y-G-D-I-S-R-G-C-D-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-N-Q-R-L-A-C-G-V-I-G-I-S-Y-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V"} +{"text": "### FUNCTION Glutaredoxin necessary for virion morphogenesis and virus replication Functions as a thiol-disulfide transfer protein between membrane-associated OPG128 and substrates OPG095 or OPG053 The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves oxidation of OPG072, OPG128 and OPG088 Exhibit thioltransferase and dehydroascorbate reductase activities in vitro ### SEQUENCE -M-K-N-V-L-I-I-F-G-K-P-Y-C-S-I-C-E-N-V-S-E-A-V-E-E-L-K-S-E-Y-D-I-L-H-V-D-I-L-S-F-F-L-K-D-G-D-S-S-M-L-G-D-V-K-R-G-T-L-I-G-N-F-A-A-H-L-S-N-Y-I-V-S-I-F-K-Y-N-P-Q-T-K-Q-M-A-F-V-D-I-N-K-S-L-D-F-T-K-T-D-K-S-L-V-N-L-E-I-L-K-S-E-I-E-K-A-N-Y-G-V-W-P-P-V-T-E"} +{"text": "### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-D-S-N-T-V-S-S-F-Q-D-I-L-M-R-M-S-K-M-Q-L-G-S-S-S-E-D-L-N-G-M-I-T-Q-F-E-S-L-K-L-Y-R-D-S-L-G-E-A-V-M-R-M-G-D-L-H-S-L-Q-N-R-N-G-K-W-R-E-Q-L-S-Q-K-F-E-E-I-R-W-L-I-E-E-V-R-H-R-L-K-I-T-E-N-S-F-E-Q-I-T-F-M-Q-A-L-Q-L-L-L-E-V-E-Q-E-I-R-T-F-S-F-Q-L-I"} +{"text": "### FUNCTION Weak suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing , a mechanism of plant viral defense that performs sequence-specific inhibition of viral mRNAs expression This could be used by the virus to infect efficiently the host the meristem cells ### SEQUENCE -M-T-C-V-L-K-G-C-V-N-E-V-T-V-L-G-H-E-T-C-S-I-G-H-A-N-K-L-R-K-Q-V-A-D-M-V-G-V-T-R-R-C-A-E-N-N-C-G-W-F-V-C-V-V-I-N-D-F-T-F-D-V-Y-N-C-C-G-R-S-H-L-E-K-C-R-K-R-V-E-T-R-N-R-E-I-W-K-Q-I-R-R-N-Q-A-E-N-M-S-A-T-A-K-K-S-H-N-S-K-T-S-K-K-K-F-K-E-D-R-E-F-G-T-P-K-R-F-L-R-D-D-V-P-F-G-I-D-R-L-F-A-F"} +{"text": "### FUNCTION Mediates the regulatory switch from transcription to RNA replication Acts late in infection by inhibiting viral transcription and up-regulating RNA replication Inhibition of transcription by protein M2-2 requires phosphorylation of the phosphoprotein ### SEQUENCE -M-N-N-S-N-I-I-I-F-P-E-K-Y-P-C-S-I-S-S-L-L-I-K-D-E-N-D-V-F-V-L-S-H-Q-N-V-L-D-C-L-Q-F-Q-Y-P-Y-N-M-Y-S-Q-N-H-M-L-D-D-I-Y-W-T-S-Q-E-L-I-E-D-V-L-K-I-L-H-L-S-G-I-S-I-N-K-Y-V-I-Y-V-L-V-L"} +{"text": "### FUNCTION The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell Acts as a functional inhibitor of gH and maintains gH in an inhibited form Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH ### SEQUENCE -M-K-I-Y-R-V-L-V-H-L-S-F-V-L-G-M-F-T-K-T-N-T-V-L-A-W-S-K-Y-D-L-V-H-G-F-M-R-V-A-N-I-S-S-I-M-R-L-D-C-L-P-N-L-L-S-S-N-A-G-Y-A-A-L-P-S-D-D-I-P-T-G-I-F-I-K-V-N-C-S-I-P-E-F-I-L-W-Y-E-Q-K-A-M-A-A-W-I-N-P-I-M-G-T-V-L-M-M-N-D-V-L-K-S-G-L-E-N-S-V-K-V-G-L-L-T-F-L-K-R-I-A-E-K-G-P-N-G-P-L-R-N-R-G-S-G-C-I-N-L-I-A-P-A-D-I-S-C-Y-G-S-T-R-L-D-R-F-N-R-D-F-E-D-D-S-R-G-M-P-C-R-A-K-A-M-R-R-T-T-S-G-S-R-R-A-N-A"} +{"text": "### FUNCTION Virion protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-Q-G-C-D-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-F-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-E-V-I-G-I-S-Y-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V"} +{"text": "### FUNCTION Glutaredoxin necessary for virion morphogenesis and virus replication Functions as a thiol-disulfide transfer protein between membrane-associated OPG128 and substrates OPG095 or OPG053 The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves oxidation of OPG072, OPG128 and OPG088 Exhibit thioltransferase and dehydroascorbate reductase activities in vitro ### SEQUENCE -M-K-N-V-L-I-I-F-G-K-P-Y-C-S-I-C-E-N-V-S-D-A-V-E-E-L-K-S-E-Y-D-I-L-H-V-D-I-L-S-F-F-L-K-D-G-D-S-S-M-L-G-D-V-K-R-G-T-L-I-G-N-F-A-A-H-L-S-N-Y-I-V-S-I-F-K-Y-N-P-Q-T-K-Q-M-A-F-V-D-I-N-K-S-L-D-F-T-K-T-D-K-S-L-V-N-L-E-I-L-K-S-E-I-E-K-A-N-Y-G-V-W-P-P-V-T-E"} +{"text": "### FUNCTION Component of the entry fusion complex , which consists of 11 proteins During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation ### SEQUENCE -M-A-S-L-L-Y-L-I-L-F-L-L-F-V-C-I-S-Y-Y-F-T-Y-Y-P-T-N-K-L-Q-A-A-V-M-E-T-D-R-E-N-A-I-I-R-Q-R-N-D-E-I-P-T-R-T-L-D-T-A-I-F-T-D-A-S-T-V-A-S-A-Q-I-H-L-Y-Y-N-S-N-I-G-K-I-I-M-S-L-N-G-K-K-H-T-F-N-L-Y-D-D-N-D-I-R-T-L-L-P-I-L-L-L-S-K"} +{"text": "### FUNCTION Has thioltransferase and dehydroascorbate reductase activities ### SEQUENCE -M-A-E-E-F-V-Q-Q-R-L-A-N-N-K-V-T-I-F-V-K-Y-T-C-P-F-C-R-N-A-L-D-I-L-N-K-F-S-F-K-R-G-A-Y-E-I-V-D-I-K-E-F-K-P-E-N-E-L-R-D-Y-F-E-Q-I-T-G-G-R-T-V-P-R-I-F-F-G-K-T-S-I-G-G-Y-S-D-L-L-E-I-D-N-M-D-A-L-G-D-I-L-S-S-I-G-V-L-R-T-C"} +{"text": "### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-D-S-N-T-V-S-S-F-Q-D-I-L-M-R-M-S-K-M-Q-L-G-S-S-S-E-D-L-N-G-M-I-I-R-L-E-S-L-K-L-Y-R-D-S-L-G-E-A-V-M-R-M-G-D-L-H-S-L-Q-S-R-N-E-K-W-R-E-Q-L-S-Q-K-F-E-E-I-R-W-L-I-E-E-V-R-H-R-L-K-N-T-E-N-S-F-E-Q-I-T-F-M-Q-A-L-Q-L-L-L-E-V-E-Q-E-I-R-T-F-S-F-Q-L-I"} +{"text": "### FUNCTION Involved in protein trafficking May serve as a receptor for ARFRP1 ### SEQUENCE -M-A-G-Q-F-R-S-Y-V-W-D-P-L-L-I-L-S-Q-I-V-L-M-Q-T-V-Y-Y-G-S-L-G-L-W-L-A-L-V-D-A-L-V-R-S-S-P-S-L-D-Q-M-F-D-A-E-I-L-G-F-S-T-P-P-G-R-L-S-M-M-S-F-V-L-N-A-L-T-C-A-L-G-L-L-Y-F-I-R-R-G-K-Q-C-L-D-F-T-V-T-V-H-F-F-H-L-L-G-C-W-L-Y-S-S-R-F-P-S-A-L-T-W-W-L-V-Q-A-V-C-I-A-L-M-A-V-I-G-E-Y-L-C-M-R-T-E-L-K-E-I-P-L-S-S-A-P-K-S-N-V"} +{"text": "### FUNCTION Guanidinium ion exporter Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons ### SEQUENCE -M-S-W-I-V-L-L-I-A-G-L-L-E-V-V-W-A-I-G-L-K-Y-T-H-G-F-T-R-L-T-P-S-I-I-T-I-A-A-M-I-V-S-I-A-M-L-S-W-A-M-R-T-L-P-V-G-T-A-Y-A-V-W-T-G-I-G-A-V-G-A-A-I-T-G-I-L-L-L-G-E-S-A-S-P-A-R-L-L-S-L-G-L-I-V-A-G-I-I-G-L-K-L-S-T-H"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-E-A-A-L-L-L-A-K-L-P-E-A-Y-Q-I-F-D-P-L-V-D-V-L-P-V-I-P-V-F-F-L-L-L-A-F-V-W-Q-A-A-V-G-F-R"} +{"text": "### FUNCTION May play a pivotal role in the interaction between Mtuberculosis and host Can enhance the survival within macrophages under stress conditions such as H These changes probably involve the p38-ERK-NF-kappa-B signaling pathway Also precipitates the macrophage death ### SEQUENCE -M-S-F-V-M-A-Y-P-E-M-L-A-A-A-A-D-T-L-Q-S-I-G-A-T-T-V-A-S-N-A-A-A-A-A-P-T-T-G-V-V-P-P-A-A-D-E-V-S-A-L-T-A-A-H-F-A-A-H-A-A-M-Y-Q-S-V-S-A-R-A-A-A-I-H-D-Q-F-V-A-T-L-A-S-S-A-S-S-Y-A-A-T-E-V-A-N-A-A-A-A-S"} +{"text": "### FUNCTION Guanidinium ion exporter Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons ### SEQUENCE -M-S-W-I-V-L-L-I-A-G-L-L-E-V-V-W-A-I-G-L-K-Y-T-H-G-F-T-R-L-T-P-S-I-I-T-I-A-A-M-I-V-S-I-A-M-L-S-W-A-M-R-T-L-P-V-G-T-A-Y-A-V-W-T-G-I-G-A-V-G-A-A-I-T-G-I-L-L-L-G-E-S-A-S-P-A-R-L-L-S-L-G-L-I-V-A-G-I-I-G-L-K-L-S-T-H"} +{"text": "### FUNCTION Guanidinium ion exporter Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons ### SEQUENCE -M-S-W-I-V-L-L-I-A-G-L-L-E-V-V-W-A-I-G-L-K-Y-T-H-G-F-T-R-L-T-P-S-I-I-T-I-A-A-M-I-V-S-I-A-M-L-S-W-A-M-R-T-L-P-V-G-T-A-Y-A-V-W-T-G-I-G-A-V-G-A-A-I-T-G-I-L-L-L-G-E-S-A-S-P-A-R-L-L-S-L-G-L-I-V-A-G-I-I-G-L-K-L-S-T-H"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-N-S-I-Y-N-L-A-Q-A-D-A-L-P-L-E-S-G-N-S-I-L-F-P-P-L-Y-D-I-V-W-S-L-I-P-F-L-I-I-L-I-V-F-W-K-L-V-L-P-K-F-Q-E-V-L-T-E-R-E-D-R-I-K-G-G-I-Q-R-A-E-A-A-Q-A-E-A-K-A-A-L-E-K-Y-N-A-Q-L-A-E-A-R-T-E-A-A-E-I-R-E-Q-A-R-E-R-G-K-Q-I-E-A-E-L-K-D-K-A-N-E-E-S-N-R-I-I-E-S-G-S-K-Q-L-L-A-Q-R-E-Q-V-V-N-E-L-R-R-E-M-G-Q-N-S-I-N-L-A-E-H-L-L-G-D-Q-L-S-D-N-V-K-R-S-G-T-I-D-R-F-L-A-D-L-D-T-V-A-P-N-G-K"} +{"text": "### FUNCTION Necessary for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine ### SEQUENCE -M-V-K-P-R-Q-R-E-Y-P-T-L-K-S-S-L-N-I-V-R-E-T-A-L-I-A-I-S-C-V-F-W-I-Y-C-L-V-V-L-L-V-Y-I-G-T-I-F-E-I-H-D-E-S-I-N-T-I-R-V-A-L-N-I-E-N-T-E-I-L-D-I-F-E-T-M-G-I-F-A-I-I-I-F-V-F-F-T-I-S-I-L-I-Q-K-W-Q-R-G-R-E-S"} +{"text": "### FUNCTION Represses transcription of the icaADBC operon necessary for biofilm production ### SEQUENCE -M-K-D-K-I-I-D-N-A-I-T-L-F-S-E-K-G-Y-D-G-T-T-L-D-D-I-A-K-S-V-N-I-K-K-A-S-L-Y-Y-H-F-D-S-K-K-S-I-Y-E-Q-S-V-K-C-C-F-D-Y-L-N-N-I-I-M-M-N-Q-N-K-S-N-Y-S-I-D-A-L-Y-Q-F-L-F-E-F-I-F-D-I-E-E-R-Y-I-R-M-Y-V-Q-L-S-N-T-P-E-E-F-S-G-N-I-Y-G-Q-I-Q-D-L-N-Q-S-L-S-K-E-I-A-K-F-Y-D-E-S-K-I-K-M-T-K-E-D-F-Q-N-L-I-L-L-F-L-E-S-W-Y-L-K-A-S-F-S-Q-K-F-G-A-V-E-E-S-K-S-Q-F-K-D-E-V-Y-S-L-L-N-I-F-L-K-K"} +{"text": "### FUNCTION Chaperone that serves for the intracellular sequestration and transport of Cu ### SEQUENCE -M-S-Q-E-I-L-N-V-E-G-M-S-C-G-H-C-K-S-A-V-E-S-A-L-N-N-I-D-G-V-T-S-A-D-V-N-L-E-N-G-Q-V-S-V-Q-Y-D-D-S-K-V-A-V-S-Q-M-K-D-A-I-E-D-Q-G-Y-D-V-V"} +{"text": "### FUNCTION Transcriptional regulator acting as an intermediary between major regulators SarA and agr and virulence genes Represses alpha-hemolysin ### SEQUENCE -M-N-D-L-K-S-K-S-N-I-K-L-M-K-R-V-L-T-T-Y-E-L-R-K-Y-L-K-K-Y-F-C-L-T-L-D-N-Y-L-V-L-A-Y-L-D-V-F-K-N-D-E-G-K-Y-F-M-R-D-I-I-S-Y-I-G-I-D-Q-S-R-I-V-K-S-V-K-E-L-S-K-K-G-Y-L-N-K-C-R-D-P-H-D-S-R-N-V-I-I-V-V-S-V-K-Q-H-N-Y-I-K-N-L-L-S-E-I-N-I-N-E-T"} +{"text": "### FUNCTION Negative regulator of sarA transcription at late exponential and stationary growth phases It contributes to the modulation of target genes downstream of the sarA regulatory cascade Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr ### SEQUENCE -M-S-K-I-N-D-I-N-D-L-V-N-A-T-F-Q-V-K-K-F-F-R-D-T-K-K-K-F-N-L-N-Y-E-E-I-Y-I-L-N-H-I-L-R-S-E-S-N-E-I-S-S-K-E-I-A-K-C-S-E-F-K-P-Y-Y-L-T-K-A-L-Q-K-L-K-D-L-K-L-L-S-K-K-R-S-L-Q-D-E-R-T-V-I-V-Y-V-T-D-T-Q-K-A-N-I-Q-K-L-I-S-E-L-E-E-Y-I-K-N"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-V-E-E-I-Q-G-N-I-A-N-L-S-N-S-E-K-Q-K-H-V-E-K-V-Y-L-E-N-S-D-L-V-K-R-I-Q-R-V-V-T-D-H-G-T-E-I-G-I-R-L-K-Q-P-I-D-L-Q-Y-G-D-I-L-Y-A-D-D-H-N-M-I-I-V-D-V-N-S-E-D-L-L-V-I-Q-P-R-T-L-Q-E-M-G-D-I-A-H-Q-L-G-N-R-H-L-P-A-Q-F-T-E-T-E-M-L-V-Q-Y-D-Y-L-V-E-D-L-L-K-S-L-G-I-P-Y-V-R-E-D-R-K-V-N-K-A-F-R-H-I-G-H-S-H-D"} +{"text": "### FUNCTION Part of the pathway by which MgrA and SarA control autolysis ### SEQUENCE -M-S-N-K-V-Q-R-F-I-E-A-E-R-E-L-S-Q-L-K-H-W-L-K-T-T-H-K-I-S-I-E-E-F-V-V-L-F-K-V-Y-E-A-E-K-I-S-G-K-E-L-R-D-T-L-H-F-E-M-L-W-D-T-S-K-I-D-V-I-I-R-K-I-Y-K-K-E-L-I-S-K-L-R-S-E-T-D-E-R-Q-V-F-Y-F-Y-S-T-S-Q-K-K-L-L-D-K-I-T-K-E-I-E-V-L-S-V-T-N"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-E-A-R-D-I-L-K-R-P-V-I-T-E-K-S-S-E-A-M-A-E-D-K-Y-T-F-D-V-D-T-R-V-N-K-T-Q-V-K-M-A-V-E-E-I-F-N-V-K-V-A-S-V-N-I-M-N-Y-K-P-K-K-K-R-M-G-R-Y-Q-G-Y-T-N-K-R-R-K-A-I-V-T-L-K-E-G-S-I-D-L-F-N"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-V-A-R-T-I-R-I-A-P-R-K-V-R-L-V-L-D-L-I-R-G-K-N-A-A-E-A-I-A-I-L-K-L-T-N-K-A-S-S-P-V-I-E-K-V-L-M-S-A-L-A-N-A-E-H-N-Y-D-M-N-T-D-E-L-V-V-K-E-A-Y-A-N-E-G-P-T-L-K-R-F-R-P-R-A-Q-G-R-A-S-A-I-N-K-R-T-S-H-I-T-I-V-V-S-D-G-K-E-E-A-K-E-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-L-P-K-R-V-K-Y-R-R-Q-H-R-P-K-T-T-G-R-S-K-G-G-N-Y-V-T-F-G-E-F-G-L-Q-A-T-T-T-S-W-I-T-S-R-Q-I-E-S-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-T-P-Y-T-K-K-P-L-E-V-R-M-G-A-G-K-G-A-V-E-G-W-I-A-V-V-K-P-G-R-I-L-F-E-V-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-T-K-F-V-K-R-E-E-L-G-G-E-T-N-E-S"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-K-V-A-D-N-S-G-A-R-E-V-L-T-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-V-I-V-C-T-V-K-N-A-T-P-G-G-V-V-K-K-G-D-V-V-K-A-V-I-V-R-T-K-S-G-V-R-R-N-D-G-S-Y-I-K-F-D-E-N-A-C-V-I-I-R-D-D-K-G-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-E-K-F-N-T-E-V-T-E-N-L-M-K-K-F-N-Y-S-S-V-M-E-V-P-K-I-D-K-I-V-V-N-M-G-V-G-D-A-V-Q-N-S-K-V-L-D-N-A-V-E-E-L-E-L-I-T-G-Q-K-P-L-V-T-K-A-K-K-S-I-A-T-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-I-S-V-S-L-P-R-V-R-D-F-Q-G-V-S-K-K-A-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-D-Y-D-K-V-S-K-V-R-G-M-D-I-V-I-V-T-T-A-N-T-D-E-E-A-R-E-L-L-A-N-F-G-M-P-F-R-K"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-K-I-I-D-I-P-S-D-V-T-V-T-F-D-G-N-H-V-T-V-K-G-P-K-G-E-L-S-R-T-L-N-E-R-M-T-F-K-Q-E-E-N-T-I-E-V-V-R-P-S-D-S-K-E-D-R-T-N-H-G-T-T-R-A-L-L-N-N-M-V-Q-G-V-S-Q-G-Y-V-K-V-L-E-L-V-G-V-G-Y-R-A-Q-M-Q-G-K-D-L-I-L-N-V-G-Y-S-H-P-V-E-I-K-A-E-E-N-I-T-F-S-V-E-K-N-T-V-V-K-V-E-G-I-S-K-E-Q-V-G-A-L-A-S-N-I-R-S-V-R-P-P-E-P-Y-K-G-K-G-I-R-Y-Q-G-E-Y-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-I-D-K-N-K-V-R-L-K-R-H-A-R-V-R-T-N-L-S-G-T-A-E-K-P-R-L-N-V-Y-R-S-N-K-H-I-Y-A-Q-I-I-D-D-N-K-G-V-T-L-A-Q-A-S-S-K-D-S-D-I-A-T-T-A-T-K-V-E-L-A-T-K-V-G-E-A-I-A-K-K-A-A-D-K-G-I-K-E-I-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-S-G-L-E-F"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-Q-T-F-M-A-N-E-S-N-I-E-R-K-W-Y-V-I-D-A-E-G-Q-T-L-G-R-L-S-S-E-V-A-S-I-L-R-G-K-N-K-V-T-Y-T-P-H-V-D-T-G-D-Y-V-I-V-I-N-A-S-K-I-E-F-T-G-N-K-E-T-D-K-V-Y-Y-R-H-S-N-H-P-G-G-I-K-S-I-T-A-G-E-L-R-R-T-N-P-E-R-L-I-E-N-S-I-K-G-M-L-P-S-T-R-L-G-E-K-Q-G-K-K-L-F-V-Y-G-G-A-E-H-P-H-A-A-Q-Q-P-E-N-Y-E-L-R-G"} +{"text": "### FUNCTION Dephosphorylates the phosphotyrosine-containing proteins ### SEQUENCE -M-K-I-L-F-V-C-T-G-N-T-C-R-S-P-L-A-E-S-I-A-K-E-V-M-P-N-H-Q-F-E-S-R-G-I-F-A-V-N-N-Q-G-V-S-N-Y-V-E-D-L-V-E-E-H-H-L-A-E-T-T-L-S-Q-Q-F-T-E-A-D-L-K-A-D-I-I-L-T-M-S-Y-S-H-K-E-L-I-E-A-H-F-G-L-Q-N-H-V-F-T-L-H-E-Y-V-K-E-A-G-E-V-I-D-P-Y-G-G-T-K-E-M-Y-V-H-T-Y-E-E-L-V-S-L-I-L-K-L-K-D-I-I-C"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-T-E-T-A-N-L-F-V-L-G-A-A-G-G-V-E-W-G-T-V-I-V-Q-V-L-T-F-I-V-L-L-A-L-L-K-K-F-A-W-G-P-L-K-D-V-M-D-K-R-E-R-D-I-N-R-D-I-D-D-A-E-Q-A-K-L-N-A-Q-K-L-E-E-E-N-K-Q-K-L-K-E-T-Q-E-E-V-Q-K-I-L-E-D-A-K-V-Q-A-R-Q-Q-Q-E-Q-I-I-H-E-A-N-V-R-A-N-G-M-I-E-T-A-Q-S-E-I-N-S-Q-K-E-R-A-I-A-D-I-N-N-Q-V-S-E-L-S-V-L-I-A-S-K-V-L-R-K-E-I-S-E-Q-D-Q-K-A-L-V-D-K-Y-L-K-E-A-G-D-K"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity ### SEQUENCE -M-L-S-F-S-Q-N-R-S-H-S-L-E-Q-S-L-K-E-G-Y-S-Q-M-A-D-L-N-L-S-L-A-N-E-A-F-P-I-E-C-E-A-C-D-C-N-E-T-Y-L-S-S-N-S-T-N-E"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA Neutralized by coexpression with cognate antitoxin MazE ### SEQUENCE -M-I-R-R-G-D-V-Y-L-A-D-L-S-P-V-Q-G-S-E-Q-G-G-V-R-P-V-V-I-I-Q-N-D-T-G-N-K-Y-S-P-T-V-I-V-A-A-I-T-G-R-I-N-K-A-K-I-P-T-H-V-E-I-E-K-K-K-Y-K-L-D-K-D-S-V-I-L-L-E-Q-I-R-T-L-D-K-K-R-L-K-E-K-L-T-Y-L-S-D-D-K-M-K-E-V-D-N-A-L-M-I-S-L-G-L-N-A-V-A-H-Q-K-N"} +{"text": "### FUNCTION Involved in countering the first line of host defense mechanisms Efficiently inhibits opsonization, phagocytosis and killing of Saureus by human neutrophils Acts by binding and stabilizing human C3 convertases ### SEQUENCE -M-K-I-R-K-S-I-L-A-G-T-L-A-I-V-L-A-S-P-L-V-T-N-L-D-K-N-E-A-Q-A-S-T-S-L-P-T-S-N-E-Y-Q-N-E-K-L-A-N-E-L-K-S-L-L-D-E-L-N-V-N-E-L-A-T-G-S-L-N-T-Y-Y-K-R-T-I-K-I-S-G-Q-K-A-M-Y-A-L-K-S-K-D-F-K-K-M-S-E-A-K-Y-Q-L-Q-K-I-Y-N-E-I-D-E-A-L-K-S-K-Y"} +{"text": "### FUNCTION Secreted tyrosine phosphatase that plays a critical role during infection as a bacterial effector protein that counteracts host defenses Required for intramacrophage survival ### SEQUENCE -M-V-D-V-A-F-V-C-L-G-N-I-C-R-S-P-M-A-E-A-I-M-R-Q-R-L-K-D-R-N-I-H-D-I-K-V-H-S-R-G-T-G-S-W-N-L-G-E-P-P-H-E-G-T-Q-K-I-L-N-K-H-N-I-P-F-D-G-M-I-S-E-L-F-E-A-T-D-D-F-D-Y-I-V-A-M-D-Q-S-N-V-D-N-I-K-S-I-N-P-N-L-K-G-Q-L-F-K-L-L-E-F-S-N-M-E-E-S-D-V-P-D-P-Y-Y-T-N-N-F-E-G-V-Y-D-M-V-L-S-S-C-D-N-L-I-D-Y-I-V-K-D-A-N-L-K-E-G"} +{"text": "### FUNCTION Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins May act as a hydrogen peroxide and organic hydroperoxide sensor ### SEQUENCE -M-S-V-E-I-E-S-I-E-H-E-L-E-E-S-I-A-S-L-R-Q-A-G-V-R-I-T-P-Q-R-Q-A-I-L-R-Y-L-I-S-S-H-T-H-P-T-A-D-E-I-Y-Q-A-L-S-P-D-F-P-N-I-S-V-A-T-I-Y-N-N-L-R-V-F-K-D-I-G-I-V-K-E-L-T-Y-G-D-S-S-S-R-F-D-F-N-T-H-N-H-Y-H-I-I-C-E-Q-C-G-K-I-V-D-F-Q-Y-P-Q-L-N-E-I-E-R-L-A-Q-H-M-T-D-F-D-V-T-H-H-R-M-E-I-Y-G-V-C-K-E-C-Q-D-K"} +{"text": "### FUNCTION Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence Also, modulates the expression of genes not previously implicated in pathogenesis ### SEQUENCE -M-H-K-L-A-H-T-S-F-G-I-V-G-M-F-V-N-T-C-M-V-A-K-Y-V-I-I-N-W-E-M-F-S-M-K-K-V-N-N-D-T-V-F-G-I-L-Q-L-E-T-L-L-G-D-I-N-S-I-F-S-E-I-E-S-E-Y-K-M-S-R-E-E-I-L-I-L-L-T-L-W-Q-K-G-S-M-T-L-K-E-M-D-R-F-V-E-V-K-P-Y-K-R-T-R-T-Y-N-N-L-V-E-L-E-W-I-Y-K-E-R-P-V-D-D-E-R-T-V-I-I-H-F-N-E-K-L-Q-Q-E-K-V-E-L-L-N-F-I-S-D-A-I-A-S-R-A-T-A-M-Q-N-S-L-N-A-I-I-A-V"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-I-I-E-T-G-G-K-Q-I-K-V-E-E-G-Q-E-I-F-V-E-K-L-D-V-N-E-G-D-T-F-T-F-D-K-V-L-F-V-G-G-D-S-V-K-V-G-A-P-T-V-E-G-A-T-V-T-A-T-V-N-K-Q-G-R-G-K-K-I-T-V-F-T-Y-K-R-R-K-N-S-K-R-K-K-G-H-R-Q-P-Y-T-K-L-T-I-D-K-I-N-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-V-K-T-T-E-K-A-E-A-R-N-I-S-Q-K-S-A-M-R-T-A-V-K-N-A-K-T-A-V-S-N-N-A-D-N-K-N-E-L-V-S-L-A-V-K-L-V-D-K-A-A-Q-S-N-L-I-H-S-N-K-A-D-R-I-K-S-Q-L-M-T-A-N-K"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-D-L-I-N-A-V-A-E-Q-A-D-L-T-K-K-E-A-G-S-A-V-D-A-V-F-E-S-I-Q-N-S-L-A-K-G-E-K-V-Q-L-I-G-F-G-N-F-E-V-R-E-R-A-A-R-K-G-R-N-P-Q-T-G-K-E-I-D-I-P-A-S-K-V-P-A-F-K-A-G-K-A-L-K-D-A-V-K"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-S-D-V-S-L-K-L-S-A-K-D-I-Y-E-K-D-F-E-K-T-M-A-R-G-Y-R-R-E-E-V-D-A-F-L-D-D-I-I-A-D-Y-Q-K-M-A-D-M-N-N-E-V-V-K-L-S-E-E-N-H-K-L-K-K-E-L-E-E-L-R-L-R-V-A-T-S-R-P-Q-D-N-K-S-F-S-S-N-N-T-T-T-N-T-S-S-N-N-V-D-I-L-K-R-I-S-N-L-E-K-A-V-F-G-K"} +{"text": "### FUNCTION Involved in cold stress response ### SEQUENCE -M-K-Q-G-T-V-K-W-F-N-A-E-K-G-F-G-F-I-E-V-E-G-E-N-D-V-F-V-H-F-S-A-I-N-Q-D-G-Y-K-S-L-E-E-G-Q-A-V-E-F-E-V-V-E-G-D-R-G-P-Q-A-A-N-V-V-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-Q-E-R-K-N-E-I-I-K-E-Y-R-V-H-E-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-A-E-I-N-A-V-N-E-H-L-R-T-H-K-K-D-H-H-S-R-R-G-L-L-K-M-V-G-R-R-R-H-L-L-N-Y-L-R-S-K-D-I-Q-R-Y-R-E-L-I-K-S-L-G-I-R-R"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-H-L-A-L-K-D-L-F-S-G-F-F-V-I-D-D-E-E-E-V-E-V-P-D-K-Q-Q-Q-V-N-E-A-P-A-K-E-Q-S-Q-Q-T-T-K-Q-N-A-I-K-S-V-P-Q-K-S-A-S-R-Y-T-T-T-S-E-E-R-N-N-R-M-S-N-Y-S-K-N-N-S-R-N-V-V-T-M-N-N-A-T-P-N-N-A-S-Q-E-S-S-K-M-C-L-F-E-P-R-V-F-S-D-T-Q-D-I-A-D-E-L-K-N-R-R-A-T-L-V-N-L-Q-R-I-D-K-V-S-A-K-R-I-I-D-F-L-S-G-T-V-Y-A-I-G-G-D-I-Q-R-V-G-T-D-I-F-L-C-T-P-D-N-V-E-V-A-G-S-I-T-D-H-I-E-N-M-E-H-S-F-D"} +{"text": "### FUNCTION Catalyzes quinol oxidation with the concomitant reduction of oxygen to water ### SEQUENCE -M-S-T-I-M-K-H-T-V-G-F-I-A-S-I-V-L-T-L-L-A-V-Y-V-T-L-Y-T-S-L-T-F-H-A-K-L-T-I-I-F-G-F-A-F-V-Q-A-G-L-Q-L-L-M-F-M-H-L-T-E-G-K-D-G-R-L-Q-T-F-K-V-I-F-A-L-V-I-T-L-C-F-V-V-G-T-Y-W-V-M-Q-G-G-H-S-S-H-L"} +{"text": "### FUNCTION Specifically inhibits the cysteine protease staphopain B ### SEQUENCE -M-Y-Q-L-Q-F-I-N-L-V-Y-D-T-T-K-L-T-H-L-E-Q-T-N-I-N-L-F-I-G-N-W-S-N-H-Q-L-Q-K-S-I-C-I-R-H-G-D-D-T-S-H-N-Q-Y-H-I-L-F-I-D-T-A-H-Q-R-I-K-F-S-S-I-D-N-E-E-I-I-Y-I-L-D-Y-D-D-T-Q-H-I-L-M-Q-T-S-S-K-Q-G-I-G-T-S-R-P-I-V-Y-E-R-L-V"} +{"text": "### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-A-N-Y-P-Q-L-N-K-E-V-Q-Q-G-E-I-K-V-V-M-H-T-N-K-G-D-M-T-F-K-L-F-P-N-I-A-P-K-T-V-E-N-F-V-T-H-A-K-N-G-Y-Y-D-G-I-T-F-H-R-V-I-N-D-F-M-I-Q-G-G-D-P-T-A-T-G-M-G-G-E-S-I-Y-G-G-A-F-E-D-E-F-S-L-N-A-F-N-L-Y-G-A-L-S-M-A-N-S-G-P-N-T-N-G-S-Q-F-F-I-V-Q-M-K-E-V-P-Q-N-M-L-S-Q-L-A-D-G-G-W-P-Q-P-I-V-D-A-Y-G-E-K-G-G-T-P-W-L-D-Q-K-H-T-V-F-G-Q-I-I-D-G-E-T-T-L-E-D-I-A-N-T-K-V-G-P-Q-D-K-P-L-H-D-V-V-I-E-S-I-D-V-E-E"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-H-T-F-L-I-V-L-L-I-I-D-C-I-A-L-I-T-V-V-L-L-Q-E-G-K-S-S-G-L-S-G-A-I-S-G-G-A-E-Q-L-F-G-K-Q-K-Q-R-G-V-D-L-F-L-N-R-L-T-I-I-L-S-I-L-F-F-V-L-M-I-C-I-S-Y-L-G-M"} +{"text": "### FUNCTION Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase ### SEQUENCE -M-I-R-F-E-I-H-G-D-N-L-T-I-T-D-A-I-R-N-Y-I-E-E-K-I-G-K-L-E-R-Y-F-N-D-V-P-N-A-V-A-H-V-K-V-K-T-Y-S-N-S-A-T-K-I-E-V-T-I-P-L-K-N-V-T-L-R-A-E-E-R-N-D-D-L-Y-A-G-I-D-L-I-N-N-K-L-E-R-Q-V-R-K-Y-K-T-R-I-N-R-K-S-R-D-R-G-D-Q-E-V-F-V-A-E-L-Q-E-M-Q-E-T-Q-V-D-N-D-A-Y-D-D-N-E-I-E-I-I-R-S-K-E-F-S-L-K-P-M-D-S-E-E-A-V-L-Q-M-N-L-L-G-H-D-F-F-V-F-T-D-R-E-T-D-G-T-S-I-V-Y-R-R-K-D-G-K-Y-G-L-I-Q-T-S-E-Q"} +{"text": "### FUNCTION Regulatory protein involved in autolytic activity, multidrug resistance and virulence ### SEQUENCE -M-S-D-Q-H-N-L-K-E-Q-L-C-F-S-L-Y-N-A-Q-R-Q-V-N-R-Y-Y-S-N-K-V-F-K-K-Y-N-L-T-Y-P-Q-F-L-V-L-T-I-L-W-D-E-S-P-V-N-V-K-K-V-V-T-E-L-A-L-D-T-G-T-V-S-P-L-L-K-R-M-E-Q-V-D-L-I-K-R-E-R-S-E-V-D-Q-R-E-V-F-I-H-L-T-D-K-S-E-T-I-R-P-E-L-S-N-A-S-D-K-V-A-S-A-S-S-L-S-Q-D-E-V-K-E-L-N-R-L-L-G-K-V-I-H-A-F-D-E-T-K-E-K"} +{"text": "### FUNCTION Involved in the regulation of virulence genes Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb Binds directly to the agr promoter region ### SEQUENCE -M-N-T-E-K-L-E-T-L-L-G-F-Y-K-Q-Y-K-A-L-S-E-Y-I-D-K-K-Y-K-L-S-L-N-D-L-A-V-L-D-L-T-M-K-H-C-K-D-E-K-V-L-M-Q-S-F-L-K-T-A-M-D-E-L-D-L-S-R-T-K-L-L-V-S-I-R-R-L-I-E-K-E-R-L-S-K-V-R-S-S-K-D-E-R-K-I-Y-I-Y-L-N-N-D-D-I-S-K-F-N-A-L-F-E-D-V-E-Q-F-L-N-I"} +{"text": "### FUNCTION Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines Requires NADPH, but not NADH, as an electron donor for its activity ### SEQUENCE -M-K-G-L-I-I-I-G-S-A-Q-V-N-S-H-T-S-A-L-A-R-Y-L-T-E-H-F-K-T-H-D-I-E-A-E-I-F-D-L-A-E-K-P-L-N-Q-L-D-F-S-G-T-T-P-S-I-D-E-I-K-Q-N-M-K-D-L-K-E-K-A-M-A-A-D-F-L-I-L-G-T-P-N-Y-H-G-S-Y-S-G-I-L-K-N-A-L-D-H-L-N-M-D-Y-F-K-M-K-P-V-G-L-I-G-N-S-G-G-I-V-S-S-E-P-L-S-H-L-R-V-I-V-R-S-L-L-G-I-A-V-P-T-Q-I-A-T-H-D-S-D-F-A-K-N-E-D-G-S-Y-Y-L-N-D-S-E-F-Q-L-R-A-R-L-F-V-D-Q-I-V-S-F-V-N-N-S-P-Y-E-H-L-K"} +{"text": "### FUNCTION Virulence factor that is important for the establishment of infection in the host EsxA is required for EsxB synthesis as well as secretion ### SEQUENCE -M-A-M-I-K-M-S-P-E-E-I-R-A-K-S-Q-S-Y-G-Q-G-S-D-Q-I-R-Q-I-L-S-D-L-T-R-A-Q-G-E-I-A-A-N-W-E-G-Q-A-F-S-R-F-E-E-Q-F-Q-Q-L-S-P-K-V-E-K-F-A-Q-L-L-E-E-I-K-Q-Q-L-N-S-T-A-D-A-V-Q-E-Q-D-Q-Q-L-S-N-N-F-G-L-Q"} +{"text": "### FUNCTION Necessary for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine ### SEQUENCE -M-V-K-P-R-Q-R-E-Y-P-T-L-K-S-S-L-N-I-V-R-E-T-A-L-I-A-I-S-C-V-F-W-I-Y-C-L-V-V-L-L-V-Y-I-G-T-I-F-E-I-H-D-E-S-I-N-T-I-R-V-A-L-N-I-E-N-T-E-I-L-D-I-F-E-T-M-G-I-F-A-I-I-I-F-V-F-F-T-I-S-I-L-I-Q-K-W-Q-R-G-R-E-S"} +{"text": "### FUNCTION Represses transcription of the icaADBC operon necessary for biofilm production ### SEQUENCE -M-K-D-K-I-I-D-N-A-I-T-L-F-S-E-K-G-Y-D-G-T-T-L-D-D-I-A-K-S-V-N-I-K-K-A-S-L-Y-Y-H-F-D-S-K-K-S-I-Y-E-Q-S-V-K-C-C-F-D-Y-L-N-N-I-I-M-M-N-Q-N-K-S-N-Y-S-I-D-A-L-Y-Q-F-L-F-E-F-I-F-D-I-E-E-R-Y-I-R-M-Y-V-Q-L-S-N-T-P-E-E-F-S-G-N-I-Y-G-Q-I-Q-D-L-N-Q-S-L-S-K-E-I-A-K-F-Y-D-E-S-K-I-K-M-T-K-E-D-F-Q-N-L-I-L-L-F-L-E-S-W-Y-L-K-A-S-F-S-Q-K-F-G-A-V-E-E-S-K-S-Q-F-K-D-E-V-Y-S-L-L-N-I-F-L-K-K"} +{"text": "### FUNCTION Negative regulator of sarA transcription at late exponential and stationary growth phases It contributes to the modulation of target genes downstream of the sarA regulatory cascade Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr ### SEQUENCE -M-S-K-I-N-D-I-N-D-L-V-N-A-T-F-Q-V-K-K-F-F-R-D-T-K-K-K-F-N-L-N-Y-E-E-I-Y-I-L-N-H-I-L-R-S-E-S-N-E-I-S-S-K-E-I-A-K-C-S-E-F-K-P-Y-Y-L-T-K-A-L-Q-K-L-K-D-L-K-L-L-S-K-K-R-S-L-Q-D-E-R-T-V-I-V-Y-V-T-D-T-Q-K-A-N-I-Q-K-L-I-S-E-L-E-E-Y-I-K-N"} +{"text": "### FUNCTION Involved in multidrug efflux ### SEQUENCE -M-I-V-N-Y-L-K-H-K-F-Y-N-L-L-T-T-M-I-V-L-F-I-F-V-L-S-G-A-I-F-L-T-F-L-G-F-G-L-Y-G-L-S-R-I-L-I-Y-F-R-L-G-D-F-T-Y-N-R-S-M-Y-D-N-L-L-Y-Y-G-S-Y-I-I-F-G-Y-F-I-I-F-A-V-E-H-L-M-D-Y-F-R-K-M-L-P-E-N-A-Y-F-R-G-A-T-F-H-L-I-S-Y-T-V-A-T-T-L-F-Y-F-I-I-H-L-N-Y-V-Y-I-N-I-D-F-W-V-I-M-V-I-I-G-F-L-Y-V-C-K-L-Q-F-Y-P-E-S-K-N-L-N-N-R-K"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA Neutralized by coexpression with cognate antitoxin MazE ### SEQUENCE -M-I-R-R-G-D-V-Y-L-A-D-L-S-P-V-Q-G-S-E-Q-G-G-V-R-P-V-V-I-I-Q-N-D-T-G-N-K-Y-S-P-T-V-I-V-A-A-I-T-G-R-I-N-K-A-K-I-P-T-H-V-E-I-E-K-K-K-Y-K-L-D-K-D-S-V-I-L-L-E-Q-I-R-T-L-D-K-K-R-L-K-E-K-L-T-Y-L-S-D-D-K-M-K-E-V-D-N-A-L-M-I-S-L-G-L-N-A-V-A-H-Q-K-N"} +{"text": "### FUNCTION Signal transduction protein, which is a major regulator of staphylococcal pathogenesis Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors Up-regulates the expression of most toxins and genes known to be necessary for biofilm formation ### SEQUENCE -M-K-K-L-Y-T-S-Y-G-T-Y-G-F-L-H-Q-I-K-I-N-N-P-T-H-Q-L-F-Q-F-S-A-S-D-T-S-V-I-F-E-E-T-D-G-E-T-V-L-K-S-P-S-I-Y-E-V-I-K-E-I-G-E-F-S-E-H-H-F-Y-C-A-I-F-I-P-S-T-E-D-H-A-Y-Q-L-E-K-K-L-I-S-V-D-D-N-F-R-N-F-G-G-F-K-S-Y-R-L-L-R-P-A-K-G-T-T-Y-K-I-Y-F-G-F-A-D-R-H-A-Y-E-D-F-K-Q-S-D-A-F-N-D-H-F-S-K-D-A-L-S-H-Y-F-G-S-S-G-Q-H-S-S-Y-F-E-R-Y-L-Y-P-I-K-E"} +{"text": "### FUNCTION Involved in cold stress response ### SEQUENCE -M-K-Q-G-T-V-K-W-F-N-A-E-K-G-F-G-F-I-E-V-E-G-E-N-D-V-F-V-H-F-S-A-I-N-Q-D-G-Y-K-S-L-E-E-G-Q-A-V-E-F-E-V-V-E-G-D-R-G-P-Q-A-A-N-V-V-K-L"} +{"text": "### FUNCTION Global regulator with both positive and negative effects that controls the expression of several virulence factors and the biofilm formation process in a cell density-dependent manner ### SEQUENCE -M-A-I-T-K-I-N-D-C-F-E-L-L-S-M-V-T-Y-A-D-K-L-K-S-L-I-K-K-E-F-S-I-S-F-E-E-F-A-V-L-T-Y-I-S-E-N-K-E-K-E-Y-Y-L-K-D-I-I-N-H-L-N-Y-K-Q-P-Q-V-V-K-A-V-K-I-L-S-Q-E-D-Y-F-D-K-K-R-N-E-H-D-E-R-T-V-L-I-L-V-N-A-Q-Q-R-K-K-I-E-S-L-L-S-R-V-N-K-R-I-T-E-A-N-N-E-I-E-L"} +{"text": "### FUNCTION Necessary for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine ### SEQUENCE -M-V-K-P-R-Q-R-E-Y-P-T-L-K-S-S-L-N-I-V-R-E-T-A-L-I-A-I-S-C-V-F-W-I-Y-C-L-V-V-L-L-V-Y-I-G-T-I-F-E-I-H-D-E-S-I-N-T-I-R-V-A-L-N-I-E-N-T-E-I-L-D-I-F-E-T-M-G-I-F-A-I-I-I-F-V-F-F-T-I-S-I-L-I-Q-K-W-Q-R-G-R-E-S"} +{"text": "### FUNCTION Represses transcription of the icaADBC operon necessary for biofilm production ### SEQUENCE -M-K-D-K-I-I-D-N-A-I-T-L-F-S-E-K-G-Y-D-G-T-T-L-D-D-I-A-K-S-V-N-I-K-K-A-S-L-Y-Y-H-F-D-S-K-K-S-I-Y-E-Q-S-V-K-C-C-F-D-Y-L-N-N-I-I-M-M-N-Q-N-K-S-N-Y-S-I-D-A-L-Y-Q-F-L-F-E-F-I-F-D-I-E-E-R-Y-I-R-M-Y-V-Q-L-S-N-T-P-E-E-F-S-G-N-I-Y-G-Q-I-Q-D-L-N-Q-S-L-S-K-E-I-A-K-F-Y-D-E-S-K-I-K-M-T-K-E-D-F-Q-N-L-I-L-L-F-L-E-S-W-Y-L-K-A-S-F-S-Q-K-F-G-A-V-E-E-S-K-S-Q-F-K-D-E-V-Y-S-L-L-N-I-F-L-K-K"} +{"text": "### FUNCTION Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, ie the esterification of glucose at the C6'' position with the carboxyl group of the C ### SEQUENCE -M-K-T-M-K-K-Y-I-K-T-A-F-F-C-S-M-Y-W-L-I-V-Q-L-N-I-A-N-L-G-T-R-I-P-D-K-Y-F-R-Q-K-Y-I-I-F-K-S-F-N-F-E-K-H-G-K-F-W-N-K-W-F-Y-V-R-K-W-K-H-K-I-L-D-G-H-Q-L-N-Q-N-I-Y-D-Q-R-H-L-M-T-I-N-T-D-E-I-E-K-M-I-I-E-T-K-R-A-E-L-I-H-W-I-S-I-L-P-V-I-I-F-N-K-G-S-R-L-V-K-Y-I-N-I-F-Y-A-M-I-A-N-V-P-I-I-I-V-Q-R-Y-N-R-P-R-L-T-Q-L-L-R-I-L-K-R-R-G-E-R-H-D"} +{"text": "### FUNCTION Chaperone that serves for the intracellular sequestration and transport of Cu ### SEQUENCE -M-S-Q-E-I-L-N-V-E-G-M-S-C-G-H-C-K-S-A-V-E-S-A-L-N-N-I-D-G-V-T-S-A-D-V-N-L-E-N-G-Q-V-S-V-Q-Y-D-D-S-K-V-A-V-S-Q-M-K-D-A-I-E-D-Q-G-Y-D-V-V"} +{"text": "### FUNCTION Transcriptional regulator acting as an intermediary between major regulators SarA and agr and virulence genes Represses alpha-hemolysin ### SEQUENCE -M-N-D-L-K-S-K-S-N-I-K-L-M-K-R-V-L-T-T-Y-E-L-R-K-Y-L-K-K-Y-F-C-L-T-L-D-N-Y-L-V-L-A-Y-L-D-V-F-K-N-D-E-G-K-Y-F-M-R-D-I-I-S-Y-I-G-I-D-Q-S-R-I-V-K-S-V-K-E-L-S-K-K-G-Y-L-N-K-C-R-D-P-H-D-S-R-N-V-I-I-V-V-S-V-K-Q-H-N-Y-I-K-N-L-L-S-E-I-N-I-N-E-T"} +{"text": "### FUNCTION Activates transcription of virulence factors alpha- and beta hemolysin genes ### SEQUENCE -M-Y-V-E-N-S-Y-L-S-K-Q-L-C-F-L-F-Y-V-S-S-K-E-I-I-K-K-Y-T-N-Y-L-K-E-Y-D-L-T-Y-T-G-Y-I-V-L-M-A-I-E-N-D-E-K-L-N-I-K-K-L-G-E-R-V-F-L-D-S-G-T-L-T-P-L-L-K-K-L-E-K-K-D-Y-V-V-R-T-R-E-E-K-D-E-R-N-L-Q-I-S-L-T-E-Q-G-K-A-I-K-S-P-L-A-E-I-S-V-K-V-F-N-E-F-N-I-S-E-R-E-A-S-D-I-I-N-N-L-R-N-F-V-S-K-N-F-D-Y-S-D-R-K"} +{"text": "### FUNCTION Negative regulator of sarA transcription at late exponential and stationary growth phases It contributes to the modulation of target genes downstream of the sarA regulatory cascade Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr ### SEQUENCE -M-S-K-I-N-D-I-N-D-L-V-N-A-T-F-Q-V-K-K-F-F-R-D-T-K-K-K-F-N-L-N-Y-E-E-I-Y-I-L-N-H-I-L-R-S-E-S-N-E-I-S-S-K-E-I-A-K-C-S-E-F-K-P-Y-Y-L-T-K-A-L-Q-K-L-K-D-L-K-L-L-S-K-K-R-S-L-Q-D-E-R-T-V-I-V-Y-V-T-D-T-Q-K-A-N-I-Q-K-L-I-S-E-L-E-E-Y-I-K-N"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-V-E-E-I-Q-G-N-I-A-N-L-S-N-S-E-K-Q-K-H-V-E-K-V-Y-L-E-N-S-D-L-V-K-R-I-Q-R-V-V-T-D-H-G-T-E-I-G-I-R-L-K-Q-P-I-D-L-Q-Y-G-D-I-L-Y-A-D-D-H-N-M-I-I-V-D-V-N-S-E-D-L-L-V-I-Q-P-R-T-L-Q-E-M-G-D-I-A-H-Q-L-G-N-R-H-L-P-A-Q-F-T-E-T-E-M-L-V-Q-Y-D-Y-L-V-E-D-L-L-K-S-L-G-I-P-Y-V-R-E-D-R-K-V-N-K-A-F-R-H-I-G-H-S-H-D"} +{"text": "### FUNCTION Part of the pathway by which MgrA and SarA control autolysis ### SEQUENCE -M-S-N-K-V-Q-R-F-I-E-A-E-R-E-L-S-Q-L-K-H-W-L-K-T-T-H-K-I-S-I-E-E-F-V-V-L-F-K-V-Y-E-A-E-K-I-S-G-K-E-L-R-D-T-L-H-F-E-M-L-W-D-T-S-K-I-D-V-I-I-R-K-I-Y-K-K-E-L-I-S-K-L-R-S-E-T-D-E-R-Q-V-F-Y-F-Y-S-T-S-Q-K-K-L-L-D-K-I-T-K-E-I-E-V-L-S-V-T-N"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-E-A-R-D-I-L-K-R-P-V-I-T-E-K-S-S-E-A-M-A-E-D-K-Y-T-F-D-V-D-T-R-V-N-K-T-Q-V-K-M-A-V-E-E-I-F-N-V-K-V-A-S-V-N-I-M-N-Y-K-P-K-K-K-R-M-G-R-Y-Q-G-Y-T-N-K-R-R-K-A-I-V-T-L-K-E-G-S-I-D-L-F-N"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-V-A-R-T-I-R-I-A-P-R-K-V-R-L-V-L-D-L-I-R-G-K-N-A-A-E-A-I-A-I-L-K-L-T-N-K-A-S-S-P-V-I-E-K-V-L-M-S-A-L-A-N-A-E-H-N-Y-D-M-N-T-D-E-L-V-V-K-E-A-Y-A-N-E-G-P-T-L-K-R-F-R-P-R-A-Q-G-R-A-S-A-I-N-K-R-T-S-H-I-T-I-V-V-S-D-G-K-E-E-A-K-E-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-L-P-K-R-V-K-Y-R-R-Q-H-R-P-K-T-T-G-R-S-K-G-G-N-Y-V-T-F-G-E-F-G-L-Q-A-T-T-T-S-W-I-T-S-R-Q-I-E-S-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-T-P-Y-T-K-K-P-L-E-V-R-M-G-A-G-K-G-A-V-E-G-W-I-A-V-V-K-P-G-R-I-L-F-E-V-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-T-K-F-V-K-R-E-E-L-G-G-E-T-N-E-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-R-N-D-R-K-V-Y-V-G-K-V-V-S-D-K-M-D-K-T-I-T-V-L-V-E-T-Y-K-T-H-K-L-Y-G-K-R-V-K-Y-S-K-K-Y-K-T-H-D-E-N-N-S-A-K-L-G-D-I-V-K-I-Q-E-T-R-P-L-S-A-T-K-R-F-R-I-V-E-I-V-E-E-S-V-I-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-K-V-A-D-N-S-G-A-R-E-V-L-T-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-V-I-V-C-T-V-K-N-A-T-P-G-G-V-V-K-K-G-D-V-V-K-A-V-I-V-R-T-K-S-G-V-R-R-N-D-G-S-Y-I-K-F-D-E-N-A-C-V-I-I-R-D-D-K-G-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-E-K-F-N-T-E-V-T-E-N-L-M-K-K-F-N-Y-S-S-V-M-E-V-P-K-I-D-K-I-V-V-N-M-G-V-G-D-A-V-Q-N-S-K-V-L-D-N-A-V-E-E-L-E-L-I-T-G-Q-K-P-L-V-T-K-A-K-K-S-I-A-T-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-I-S-V-S-L-P-R-V-R-D-F-Q-G-V-S-K-K-A-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-D-Y-D-K-V-S-K-V-R-G-M-D-I-V-I-V-T-T-A-N-T-D-E-E-A-R-E-L-L-A-N-F-G-M-P-F-R-K"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-K-I-I-D-I-P-S-D-V-T-V-T-F-D-G-N-H-V-T-V-K-G-P-K-G-E-L-S-R-T-L-N-E-R-M-T-F-K-Q-E-E-N-T-I-E-V-V-R-P-S-D-S-K-E-D-R-T-N-H-G-T-T-R-A-L-L-N-N-M-V-Q-G-V-S-Q-G-Y-V-K-V-L-E-L-V-G-V-G-Y-R-A-Q-M-Q-G-K-D-L-I-L-N-V-G-Y-S-H-P-V-E-I-K-A-E-E-N-I-T-F-S-V-E-K-N-T-V-V-K-V-E-G-I-S-K-E-Q-V-G-A-L-A-S-N-I-R-S-V-R-P-P-E-P-Y-K-G-K-G-I-R-Y-Q-G-E-Y-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-I-D-K-N-K-V-R-L-K-R-H-A-R-V-R-T-N-L-S-G-T-A-E-K-P-R-L-N-V-Y-R-S-N-K-H-I-Y-A-Q-I-I-D-D-N-K-G-V-T-L-A-Q-A-S-S-K-D-S-D-I-A-T-T-A-T-K-V-E-L-A-T-K-V-G-E-A-I-A-K-K-A-A-D-K-G-I-K-E-I-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-S-G-L-E-F"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-Q-T-F-M-A-N-E-S-N-I-E-R-K-W-Y-V-I-D-A-E-G-Q-T-L-G-R-L-S-S-E-V-A-S-I-L-R-G-K-N-K-V-T-Y-T-P-H-V-D-T-G-D-Y-V-I-V-I-N-A-S-K-I-E-F-T-G-N-K-E-T-D-K-V-Y-Y-R-H-S-N-H-P-G-G-I-K-S-I-T-A-G-E-L-R-R-T-N-P-E-R-L-I-E-N-S-I-K-G-M-L-P-S-T-R-L-G-E-K-Q-G-K-K-L-F-V-Y-G-G-A-E-H-P-H-A-A-Q-Q-P-E-N-Y-E-L-R-G"} +{"text": "### FUNCTION Involved in multidrug efflux ### SEQUENCE -M-I-V-N-Y-L-K-H-K-F-Y-N-L-L-T-T-M-I-V-L-F-I-F-V-L-S-G-A-I-F-L-T-F-L-G-F-G-L-Y-G-L-S-R-I-L-I-Y-F-R-L-G-D-F-T-Y-N-R-S-M-Y-D-N-L-L-Y-Y-G-S-Y-I-I-F-G-Y-F-I-I-F-A-V-E-H-L-M-D-Y-F-R-K-M-L-P-E-N-A-Y-F-R-G-A-T-F-H-L-I-S-Y-T-V-A-T-T-L-F-Y-F-I-I-H-L-N-Y-V-Y-I-N-I-D-F-W-V-I-M-V-I-I-G-F-L-Y-V-C-K-L-Q-F-Y-P-E-S-K-N-L-N-N-R-K"} +{"text": "### FUNCTION Dephosphorylates the phosphotyrosine-containing proteins ### SEQUENCE -M-K-I-L-F-V-C-T-G-N-T-C-R-S-P-L-A-E-S-I-A-K-E-V-M-P-N-H-Q-F-E-S-R-G-I-F-A-V-N-N-Q-G-V-S-N-Y-V-E-D-L-V-E-E-H-H-L-A-E-T-T-L-S-Q-Q-F-T-E-A-D-L-K-A-D-I-I-L-T-M-S-Y-S-H-K-E-L-I-E-A-H-F-G-L-Q-N-H-V-F-T-L-H-E-Y-V-K-E-A-G-E-V-I-D-P-Y-G-G-T-K-E-M-Y-V-H-T-Y-E-E-L-V-S-L-I-L-K-L-K-D-I-I-C"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity ### SEQUENCE -M-L-S-F-S-Q-N-R-S-H-S-L-E-Q-S-L-K-E-G-Y-S-Q-M-A-D-L-N-L-S-L-A-N-E-A-F-P-I-E-C-E-A-C-D-C-N-E-T-Y-L-S-S-N-S-T-N-E"} +{"text": "### FUNCTION Secreted tyrosine phosphatase that plays a critical role during infection as a bacterial effector protein that counteracts host defenses Required for intramacrophage survival ### SEQUENCE -M-V-D-V-A-F-V-C-L-G-N-I-C-R-S-P-M-A-E-A-I-M-R-Q-R-L-K-D-R-N-I-H-D-I-K-V-H-S-R-G-T-G-S-W-N-L-G-E-P-P-H-E-G-T-Q-K-I-L-N-K-H-N-I-P-F-D-G-M-I-S-E-L-F-E-A-T-D-D-F-D-Y-I-V-A-M-D-Q-S-N-V-D-N-I-K-S-I-N-P-N-L-K-G-Q-L-F-K-L-L-E-F-S-N-M-E-E-S-D-V-P-D-P-Y-Y-T-N-N-F-E-G-V-Y-D-M-V-L-S-S-C-D-N-L-I-D-Y-I-V-K-D-A-N-L-K-E-G"} +{"text": "### FUNCTION Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins May act as a hydrogen peroxide and organic hydroperoxide sensor ### SEQUENCE -M-S-V-E-I-E-S-I-E-H-E-L-E-E-S-I-A-S-L-R-Q-A-G-I-R-I-T-P-Q-R-Q-A-I-L-R-Y-L-I-S-S-H-T-H-P-T-A-D-E-I-Y-Q-A-L-S-P-D-F-P-N-I-S-V-A-T-I-Y-N-N-L-R-V-F-K-D-I-G-I-V-K-E-L-T-Y-G-D-S-S-S-R-F-D-F-N-T-H-N-H-Y-H-I-I-C-E-Q-C-G-K-I-V-D-F-Q-Y-P-Q-L-N-E-I-E-R-L-A-Q-H-M-T-D-F-D-V-T-H-H-R-M-E-I-Y-G-V-C-K-E-C-Q-D-K"} +{"text": "### FUNCTION Signal transduction protein, which is a major regulator of staphylococcal pathogenesis Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors Up-regulates the expression of most toxins and genes known to be necessary for biofilm formation ### SEQUENCE -M-K-K-L-Y-T-S-Y-G-T-Y-G-F-L-H-Q-I-K-I-N-N-P-T-H-Q-L-F-Q-F-S-A-S-D-T-S-V-I-F-E-E-T-D-G-E-T-V-L-K-S-P-S-I-Y-E-V-I-K-E-I-G-E-F-S-E-H-H-F-Y-C-A-I-F-I-P-S-T-E-D-H-A-Y-Q-L-E-K-K-L-I-S-V-D-D-N-F-R-N-F-G-G-F-K-S-Y-R-L-L-R-P-A-K-G-T-T-Y-K-I-Y-F-G-F-A-D-R-H-A-Y-E-D-F-K-Q-S-D-A-F-N-D-H-F-S-K-D-A-L-S-H-Y-F-G-S-S-G-Q-H-S-S-Y-F-E-R-Y-L-Y-P-I-K-E"} +{"text": "### FUNCTION Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival ### SEQUENCE -M-K-F-N-D-V-Y-N-K-H-H-K-I-I-H-H-L-L-K-K-Y-N-I-S-Y-N-Y-D-E-Y-Y-Q-L-L-L-I-K-M-W-Q-L-S-Q-I-Y-K-P-S-S-K-Q-S-L-S-S-F-L-F-T-R-L-N-Y-Y-L-I-D-L-F-R-Q-Q-N-Q-L-K-D-V-I-L-C-E-N-N-S-P-T-L-T-E-Q-P-T-Y-F-N-E-H-D-L-R-L-Q-D-I-F-K-L-L-N-H-R-E-R-L-W-L-K-L-Y-L-E-G-Y-K-Q-F-E-I-A-E-I-M-S-L-S-L-S-T-I-K-L-I-K-M-S-V-K-R-K-C-Q-H-N-F-N"} +{"text": "### FUNCTION Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence Also, modulates the expression of genes not previously implicated in pathogenesis ### SEQUENCE -M-H-K-L-A-H-T-S-F-G-I-V-G-M-F-V-N-T-C-M-V-A-K-Y-V-I-I-N-W-E-M-F-S-M-K-K-V-N-N-D-T-V-F-G-I-L-Q-L-E-T-L-L-G-D-I-N-S-I-F-S-E-I-E-S-E-Y-K-M-S-R-E-E-I-L-I-L-L-T-L-W-Q-K-G-S-M-T-L-K-E-M-D-R-F-V-E-V-K-P-Y-K-R-T-R-T-Y-N-N-L-V-E-L-E-W-I-Y-K-E-R-P-V-D-D-E-R-T-V-I-I-H-F-N-E-K-L-Q-Q-E-K-V-E-L-L-N-F-I-S-D-A-I-A-S-R-A-T-A-M-Q-N-S-L-N-A-I-I-A-V"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-I-I-E-T-G-G-K-Q-I-K-V-E-E-G-Q-E-I-F-V-E-K-L-D-V-N-E-G-D-T-F-T-F-D-K-V-L-F-V-G-G-D-S-V-K-V-G-A-P-T-V-E-G-A-T-V-T-A-T-V-N-K-Q-G-R-G-K-K-I-T-V-F-T-Y-K-R-R-K-N-S-K-R-K-K-G-H-R-Q-P-Y-T-K-L-T-I-D-K-I-N-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-V-K-T-T-E-K-A-E-A-R-N-I-S-Q-K-S-A-M-R-T-A-V-K-N-A-K-T-A-V-S-N-N-A-D-N-K-N-E-L-V-S-L-A-V-K-L-V-D-K-A-A-Q-S-N-L-I-H-S-N-K-A-D-R-I-K-S-Q-L-M-T-A-N-K"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-D-L-I-N-A-V-A-E-Q-A-D-L-T-K-K-E-A-G-S-A-V-D-A-V-F-E-S-I-Q-N-S-L-A-K-G-E-K-V-Q-L-I-G-F-G-N-F-E-V-R-E-R-A-A-R-K-G-R-N-P-Q-T-G-K-E-I-D-I-P-A-S-K-V-P-A-F-K-A-G-K-A-L-K-D-A-V-K"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-S-D-V-S-L-K-L-S-A-K-D-I-Y-E-K-D-F-E-K-T-M-A-R-G-Y-R-R-E-E-V-D-A-F-L-D-D-I-I-A-D-Y-Q-K-M-A-D-M-N-N-E-V-V-K-L-S-E-E-N-H-K-L-K-K-E-L-E-E-L-R-L-R-V-A-T-S-R-P-Q-D-N-K-S-F-S-S-N-N-T-T-T-N-T-S-S-N-N-V-D-I-L-K-R-I-S-N-L-E-K-A-V-F-G-K"} +{"text": "### FUNCTION Involved in cold stress response ### SEQUENCE -M-K-Q-G-T-V-K-W-F-N-A-E-K-G-F-G-F-I-E-V-E-G-E-N-D-V-F-V-H-F-S-A-I-N-Q-D-G-Y-K-S-L-E-E-G-Q-A-V-E-F-E-V-V-E-G-D-R-G-P-Q-A-A-N-V-V-K-L"} +{"text": "### FUNCTION Accessory element involved in the expression of sarA and several virulence factors Modulates SarA production and/or function in a strain-dependent manner Affects the transcription of the accessory gene regulator ### SEQUENCE -M-K-Y-L-I-L-S-L-V-A-N-L-L-V-F-G-V-L-S-A-I-G-L-N-I-N-I-L-A-A-M-M-I-V-L-V-I-P-I-M-I-S-G-I-L-F-F-K-T-N-I-D-K-T-Y-I-F-F-N-I-I-F-I-D-F-Y-Y-Y-I-Y-N-V-H-L-M-T-L-P-K-F-N-N-Y-I-K-A-E-M-M-E-L-E-D-I-D-V-L-I-T-S-K-D-F-G-F-D-E-I-L-F-Y-T-L-Y-L-L-L-I-L-I-V-L-Y-Y-L-K-K-Q-V-K-H-K-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-Q-E-R-K-N-E-I-I-K-E-Y-R-V-H-E-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-A-E-I-N-A-V-N-E-H-L-R-T-H-K-K-D-H-H-S-R-R-G-L-L-K-M-V-G-R-R-R-H-L-L-N-Y-L-R-S-K-D-I-Q-R-Y-R-E-L-I-K-S-L-G-I-R-R"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-H-L-A-L-K-D-L-F-S-G-F-F-V-I-D-D-E-E-E-V-E-V-P-D-K-Q-Q-Q-V-N-E-A-P-A-K-E-Q-S-Q-Q-T-T-K-Q-N-A-I-K-S-V-P-Q-K-S-A-S-R-Y-T-T-T-S-E-E-R-N-N-R-M-S-N-Y-S-K-N-N-S-R-N-V-V-T-M-N-N-A-T-P-N-N-A-S-Q-E-S-S-K-M-C-L-F-E-P-R-V-F-S-D-T-Q-D-I-A-D-E-L-K-N-R-R-A-T-L-V-N-L-Q-R-I-D-K-V-S-A-K-R-I-I-D-F-L-S-G-T-V-Y-A-I-G-G-D-I-Q-R-V-G-T-D-I-F-L-C-T-P-D-N-V-E-V-A-G-S-I-T-D-H-I-E-N-M-E-H-S-F-D"} +{"text": "### FUNCTION May be involved in countering the first line of host defense mechanisms Impairs the leukocyte response to FPRL1 agonists by binding directly to host FPRL1 ### SEQUENCE -M-K-K-N-I-T-K-T-I-I-A-S-T-V-I-A-A-G-L-L-T-Q-T-N-D-A-K-A-F-F-S-Y-E-W-K-G-L-E-I-A-K-N-L-A-D-Q-A-K-K-D-D-E-R-I-D-K-L-M-K-E-S-D-K-N-L-T-P-Y-K-A-E-T-V-N-D-L-Y-L-I-V-K-K-L-S-Q-G-D-V-K-K-A-V-V-R-I-K-D-G-G-P-R-D-Y-Y-T-F-D-L-T-R-P-L-E-E-N-R-K-N-I-K-V-V-K-N-G-E-I-D-S-I-Y-W-D"} +{"text": "### FUNCTION Catalyzes quinol oxidation with the concomitant reduction of oxygen to water ### SEQUENCE -M-S-T-I-M-K-H-T-V-G-F-I-A-S-I-V-L-T-L-L-A-V-Y-V-T-L-Y-T-S-L-T-F-H-A-K-L-T-I-I-F-G-F-A-F-V-Q-A-G-L-Q-L-L-M-F-M-H-L-T-E-G-K-D-G-R-L-Q-T-F-K-V-I-F-A-L-V-I-T-L-C-F-V-V-G-T-Y-W-V-M-Q-G-G-H-S-S-H-L"} +{"text": "### FUNCTION Specifically inhibits the cysteine protease staphopain B ### SEQUENCE -M-Y-Q-L-Q-F-I-N-L-V-Y-D-T-T-K-L-T-H-L-E-Q-T-N-I-N-L-F-I-G-N-W-S-N-H-Q-L-Q-K-S-I-C-I-R-H-G-D-D-T-S-H-N-Q-Y-H-I-L-F-I-D-T-A-H-Q-R-I-K-F-S-S-I-D-N-E-E-I-T-Y-I-L-D-Y-D-D-T-Q-H-I-L-M-Q-T-S-S-K-Q-G-I-G-T-S-R-P-I-V-Y-E-R-L-V"} +{"text": "### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-A-N-Y-P-Q-L-N-K-E-V-Q-Q-G-E-I-K-V-V-M-H-T-N-K-G-D-M-T-F-K-L-F-P-N-I-A-P-K-T-V-E-N-F-V-T-H-A-K-N-G-Y-Y-D-G-I-T-F-H-R-V-I-N-D-F-M-I-Q-G-G-D-P-T-A-T-G-M-G-G-E-S-I-Y-G-G-A-F-E-D-E-F-S-L-N-A-F-N-L-Y-G-A-L-S-M-A-N-S-G-P-N-T-N-G-S-Q-F-F-I-V-Q-M-K-E-V-P-Q-N-M-L-S-Q-L-A-D-G-G-W-P-Q-P-I-V-D-A-Y-G-E-K-G-G-T-P-W-L-D-Q-K-H-T-V-F-G-Q-I-I-D-G-E-T-T-L-E-D-I-A-N-T-K-V-G-P-Q-D-K-P-L-H-D-V-V-I-E-S-I-D-V-E-E"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-H-T-F-L-I-V-L-L-I-I-D-C-I-A-L-I-T-V-V-L-L-Q-E-G-K-S-S-G-L-S-G-A-I-S-G-G-A-E-Q-L-F-G-K-Q-K-Q-R-G-V-D-L-F-L-N-R-L-T-I-I-L-S-I-L-F-F-V-L-M-I-C-I-S-Y-L-G-M"} +{"text": "### FUNCTION Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase ### SEQUENCE -M-I-R-F-E-I-H-G-D-N-L-T-I-T-D-A-I-R-N-Y-I-E-E-K-I-G-K-L-E-R-Y-F-N-D-V-P-N-A-V-A-H-V-K-V-K-T-Y-S-N-S-A-T-K-I-E-V-T-I-P-L-K-N-V-T-L-R-A-E-E-R-N-D-D-L-Y-A-G-I-D-L-I-N-N-K-L-E-R-Q-V-R-K-Y-K-T-R-I-N-R-K-S-R-D-R-G-D-Q-E-V-F-V-A-E-L-Q-E-M-Q-E-T-Q-V-D-N-D-A-Y-D-D-N-E-I-E-I-I-R-S-K-E-F-S-L-K-P-M-D-S-E-E-A-V-L-Q-M-N-L-L-G-H-D-F-F-V-F-T-D-R-E-T-D-G-T-S-I-V-Y-R-R-K-D-G-K-Y-G-L-I-Q-T-S-E-Q"} +{"text": "### FUNCTION Regulatory protein involved in autolytic activity, multidrug resistance and virulence ### SEQUENCE -M-S-D-Q-H-N-L-K-E-Q-L-C-F-S-L-Y-N-A-Q-R-Q-V-N-R-Y-Y-S-N-K-V-F-K-K-Y-N-L-T-Y-P-Q-F-L-V-L-T-I-L-W-D-E-S-P-V-N-V-K-K-V-V-T-E-L-A-L-D-T-G-T-V-S-P-L-L-K-R-M-E-Q-V-D-L-I-K-R-E-R-S-E-V-D-Q-R-E-V-F-I-H-L-T-D-K-S-E-T-I-R-P-E-L-S-N-A-S-D-K-V-A-S-A-S-S-L-S-Q-D-E-V-K-E-L-N-R-L-L-G-K-V-I-H-A-F-D-E-T-K-E-K"} +{"text": "### FUNCTION Involved in the regulation of virulence genes Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb Binds directly to the agr promoter region ### SEQUENCE -M-N-T-E-K-L-E-T-L-L-G-F-Y-K-Q-Y-K-A-L-S-E-Y-I-D-K-K-Y-K-L-S-L-N-D-L-A-V-L-D-L-T-M-K-H-C-K-D-E-K-V-L-M-Q-S-F-L-K-T-A-M-D-E-L-D-L-S-R-T-K-L-L-V-S-I-R-R-L-I-E-K-E-R-L-S-K-V-R-S-S-K-D-E-R-K-I-Y-I-Y-L-N-N-D-D-I-S-K-F-N-A-L-F-E-D-V-E-Q-F-L-N-I"} +{"text": "### FUNCTION Global regulator with both positive and negative effects that controls the expression of several virulence factors and the biofilm formation process in a cell density-dependent manner ### SEQUENCE -M-A-I-T-K-I-N-D-C-F-E-L-L-S-M-V-T-Y-A-D-K-L-K-S-L-I-K-K-E-F-S-I-S-F-E-E-F-A-V-L-T-Y-I-S-E-N-K-E-K-E-Y-Y-L-K-D-I-I-N-H-L-N-Y-K-Q-P-Q-V-V-K-A-V-K-I-L-S-Q-E-D-Y-F-D-K-K-R-N-E-H-D-E-R-T-V-L-I-L-V-N-A-Q-Q-R-K-K-I-E-S-L-L-S-R-V-N-K-R-I-T-E-A-N-N-E-I-E-L"} +{"text": "### FUNCTION Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines Requires NADPH, but not NADH, as an electron donor for its activity ### SEQUENCE -M-K-G-L-I-I-I-G-S-A-Q-V-N-S-H-T-S-A-L-A-R-Y-L-T-E-H-F-K-T-H-D-I-E-A-E-I-F-D-L-A-E-K-P-L-N-Q-L-D-F-S-G-T-T-P-S-I-D-E-I-K-Q-N-M-K-D-L-K-E-K-A-M-A-A-D-F-L-I-L-G-T-P-N-Y-H-G-S-Y-S-G-I-L-K-N-A-L-D-H-L-N-M-D-Y-F-K-M-K-P-V-G-L-I-G-N-S-G-G-I-V-S-S-E-P-L-S-H-L-R-V-I-V-R-S-L-L-G-I-A-V-P-T-Q-I-A-T-H-D-S-D-F-A-K-N-E-D-G-S-Y-Y-L-N-D-S-E-F-Q-L-R-A-R-L-F-V-D-Q-I-V-S-F-V-N-N-S-P-Y-E-H-L-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-V-P-D-K-N-A-T-S-E-D-S-E-E-A"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-R-N-E-I-F-E-K-I-M-R-L-E-M-N-V-N-Q-L-S-K-E-T-S-E-L-K-A-H-A-V-E-L-V-E-E-N-V-A-L-Q-L-E-N-D-N-L-K-K-V-L-G-N-D-E-P-T-T-I-D-T-A-N-S-K-P-A-K-A-V-K-K-P-L-P-S-K-D-N-L-A-I-L-Y-G-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-F-C-L-E-V-L-S-D"} +{"text": "### FUNCTION Virulence factor that is important for the establishment of infection in the host EsxB is required for EsxA synthesis as well as secretion ### SEQUENCE -M-G-G-Y-K-G-I-K-A-D-G-G-K-V-N-Q-A-K-Q-L-A-A-K-I-A-K-D-I-E-A-C-Q-K-Q-T-Q-Q-L-A-E-Y-I-E-G-S-D-W-E-G-Q-F-A-N-K-V-K-D-V-L-L-I-M-A-K-F-Q-E-E-L-V-Q-P-M-A-D-H-Q-K-A-I-D-N-L-S-Q-N-L-A-K-Y-D-T-L-S-I-K-Q-G-L-D-R-V-N-P"} +{"text": "### FUNCTION Component of the ESAT-6 secretion system Required for the secretion of EsxA and EsxB ### SEQUENCE -M-L-M-N-S-V-I-A-L-T-F-L-T-A-S-S-N-N-G-G-L-N-I-D-V-Q-Q-E-E-E-K-R-I-N-N-D-L-N-Q-Y-D-T-T-L-F-N-K-D-S-K-E-V-N-D-A-I-A-K-Q-K-K-E-R-Q-Q-Q-I-K-N-D-M-F-Q-N-Q-A-S-H-S-T-R-L-N-E-T-K-K-V-L-F-S-K-S-N-L-E-K-T-S-E-S-D-K-S-P-Y-I-Q-N-K-Q-E-K-K-I-F-P-Y-I-L-M-S-V-G-A-F-L-T-L-G-F-V-I-F-S-I-H-K-G-R-R-T-K-N-E-S-A-R-K-S-N-I"} +{"text": "### FUNCTION Virulence factor that is important for the establishment of infection in the host EsxA is required for EsxB synthesis as well as secretion ### SEQUENCE -M-A-M-I-K-M-S-P-E-E-I-R-A-K-S-Q-S-Y-G-Q-G-S-D-Q-I-R-Q-I-L-S-D-L-T-R-A-Q-G-E-I-A-A-N-W-E-G-Q-A-F-S-R-F-E-E-Q-F-Q-Q-L-S-P-K-V-E-K-F-A-Q-L-L-E-E-I-K-Q-Q-L-N-S-T-A-D-A-V-Q-E-Q-D-Q-Q-L-S-N-N-F-G-L-Q"} +{"text": "### FUNCTION Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage ### SEQUENCE -M-L-Q-S-I-P-A-L-P-V-G-D-I-K-K-S-I-G-F-Y-C-D-K-L-G-F-T-L-V-H-H-E-D-G-F-A-V-L-M-C-N-E-V-R-I-H-L-W-E-A-S-D-E-G-W-R-S-R-S-N-D-S-P-V-C-T-G-A-E-S-F-I-A-G-T-A-S-C-R-I-E-V-E-G-I-D-E-L-Y-Q-H-I-K-P-L-G-I-L-H-P-N-T-S-L-K-D-Q-W-W-D-E-R-D-F-A-V-I-D-P-D-N-N-L-I-S-F-F-Q-Q-I-K-S"} +{"text": "### FUNCTION Involved in the temperature-dependent positive control of flagellum-driven swimming motility and cellular aggregation Regulates fliC expression by directly interacting with fliC promoter ### SEQUENCE -M-T-L-R-N-K-A-F-H-Q-L-R-Q-L-F-Q-Q-H-T-A-R-W-Q-H-E-L-P-D-L-T-K-P-Q-Y-A-V-M-R-A-I-A-D-K-P-G-I-E-Q-V-A-L-I-E-A-A-V-S-T-K-A-T-L-A-E-M-L-A-R-M-E-N-R-G-L-V-R-R-E-H-D-A-A-D-K-R-R-R-F-V-W-L-T-A-E-G-E-K-I-L-A-A-A-I-P-I-G-D-S-V-D-E-E-F-L-G-R-L-S-A-E-E-Q-E-L-F-V-Q-L-V-R-K-M-M-N-T"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-S-K-E-Q-K-T-P-E-G-Q-A-P-E-E-I-I-M-D-Q-H-E-E-I-E-A-V-E-P-E-A-S-A-E-Q-V-D-P-R-D-E-K-I-A-N-L-E-A-Q-L-A-E-A-Q-T-R-E-R-D-G-I-L-R-V-K-A-E-M-E-N-L-R-R-R-T-E-L-D-I-E-K-A-H-K-F-A-L-E-K-F-I-N-E-L-L-P-V-I-D-S-L-D-R-A-L-E-V-A-D-K-A-N-P-D-M-S-A-M-V-E-G-I-E-L-T-L-K-S-M-L-D-V-V-R-K-F-G-V-E-V-I-A-E-T-N-V-P-L-D-P-N-V-H-Q-A-I-A-M-V-E-S-D-D-V-A-P-G-N-V-L-G-I-M-Q-K-G-Y-T-L-N-G-R-T-I-R-A-A-M-V-T-V-A-K-A-K-A"} +{"text": "### FUNCTION Participates in cysteine desulfuration mediated by SufS Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process ### SEQUENCE -M-A-L-L-P-D-K-E-K-L-L-R-N-F-L-R-C-A-N-W-E-E-K-Y-L-Y-I-I-E-L-G-Q-R-L-P-E-L-R-D-E-D-R-S-P-Q-N-S-I-Q-G-C-Q-S-Q-V-W-I-V-M-R-Q-N-A-Q-G-I-I-E-L-Q-G-D-S-D-A-A-I-V-K-G-L-I-A-V-V-F-I-L-Y-D-Q-M-T-P-Q-D-V-V-N-F-D-V-R-P-W-F-E-K-M-A-L-T-Q-H-L-T-P-S-R-S-Q-G-L-E-A-M-I-R-A-I-R-A-K-A-A-A-L-S"} +{"text": "### FUNCTION Broad mercury transporter that mediates the transport of both CH across the membrane ### SEQUENCE -M-N-A-P-D-K-L-P-P-E-T-R-Q-P-V-S-G-Y-L-W-G-A-L-A-V-L-T-C-P-C-H-L-P-I-L-A-A-V-L-A-G-T-T-A-G-A-F-L-G-E-H-W-G-V-A-A-L-A-L-T-G-L-F-V-L-A-V-T-R-L-L-R-A-F-R-G-G-S"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-S-E-V-T-S-A-K-A-V-A-K-T-V-R-I-A-P-R-K-A-R-I-V-I-D-L-I-R-G-K-Q-V-G-E-A-I-A-I-L-K-Y-T-P-R-S-A-S-P-I-I-E-K-V-L-K-S-A-I-A-N-A-E-H-N-Y-D-L-D-I-N-N-L-V-V-E-E-A-F-V-D-E-G-P-T-L-K-R-F-R-P-R-A-Q-G-R-A-S-A-I-N-K-R-T-S-H-I-T-V-V-V-S-E-V-K-E-G"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-Y-R-R-E-F-R-G-N-M-R-G-R-A-K-G-G-T-E-V-A-F-G-E-Y-G-L-Q-A-V-E-A-S-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-S-K-P-I-G-V-R-M-G-K-G-K-G-A-P-E-G-W-V-S-P-V-K-R-G-K-I-M-F-E-I-A-G-V-P-E-D-V-A-R-E-A-L-R-L-A-A-H-K-L-P-V-K-T-K-I-V-K-R-E-E-I-G-G-E-A-N-E-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-D-R-N-Q-R-K-V-Y-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-Y-K-K-H-G-L-Y-G-K-R-V-K-Y-S-K-K-F-K-A-H-D-E-N-N-I-A-K-T-G-D-V-V-R-I-S-E-T-R-P-L-S-A-T-K-H-F-R-L-L-E-V-V-E-E-A-V-I-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-M-K-V-A-D-N-S-G-A-R-E-V-L-T-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-V-V-V-C-T-V-K-Q-A-T-P-G-G-V-V-K-K-G-E-V-V-K-A-V-I-V-R-T-K-S-G-A-R-R-Q-D-G-S-Y-I-K-F-D-E-N-A-C-V-I-I-R-D-D-K-S-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-N-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-D-Q-Y-L-K-E-I-V-P-A-L-M-S-K-F-N-Y-D-S-V-M-E-V-P-K-I-D-K-I-V-I-N-T-G-V-G-D-A-T-A-N-A-K-V-L-D-S-A-V-E-E-L-A-L-I-T-G-Q-K-P-V-I-T-K-A-K-N-S-I-A-G-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-R-M-Y-D-F-L-D-K-L-V-T-V-S-L-P-R-V-R-D-F-R-G-V-S-K-K-A-F-D-G-R-G-N-Y-T-L-G-V-R-E-Q-L-I-F-P-E-I-D-Y-D-Q-V-S-K-V-R-G-M-D-V-V-I-V-T-T-A-K-S-D-E-E-S-H-E-L-L-T-Q-L-G-M-P-F-Q-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-Q-E-R-K-N-E-I-I-A-E-Y-R-V-H-D-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-A-E-I-N-S-L-N-E-H-V-R-V-H-K-K-D-H-H-S-Y-R-G-L-M-K-M-V-G-H-R-R-N-L-L-T-Y-L-R-K-K-D-V-Q-R-Y-R-E-L-I-K-R-L-G-L-R-R"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-F-K-V-F-Y-Q-E-T-L-T-E-T-P-V-R-E-K-T-Q-S-L-Y-V-E-A-E-S-E-V-K-V-R-Q-L-L-K-D-E-P-F-H-I-E-F-V-E-K-I-S-D-A-H-L-A-Y-E-K-E-N-P-D-F-A-L-W-E-K"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-F-K-E-Y-K-I-Y-K-F-F-E-Q-V-K-Q-E-T-Y-K-V-V-W-P-T-R-K-E-L-V-A-S-T-L-V-V-V-V-A-V-F-I-F-S-L-I-C-L-V-L-D-Y-S-I-H-N-I-M-Q-L-L-L-N-I-G-K"} +{"text": "### FUNCTION Lanthionine-containing peptide devoid of antibiotic properties, involved in the formation of aerial mycelium Suggested to self-assemble at air-water interfaces, thus providing a film of surfactant through which nascent aerial hyphae can emerge The aerial hyphae differentiate further into spores ### SEQUENCE -M-N-L-F-D-L-Q-S-M-E-T-P-K-E-E-A-M-G-D-V-E-T-G-S-R-A-S-L-L-L-C-G-D-S-S-L-S-I-T-T-C-N"} +{"text": "### FUNCTION Involved in UV protection and mutation ### SEQUENCE -M-S-T-V-Y-H-R-P-A-D-P-S-G-D-D-S-Y-V-R-P-L-F-A-D-R-C-Q-A-G-F-P-S-P-A-T-D-Y-A-E-Q-E-L-D-L-N-S-Y-C-I-S-R-P-A-A-T-F-F-L-R-A-S-G-E-S-M-N-Q-A-G-V-Q-N-G-D-L-L-V-V-D-R-A-E-K-P-Q-H-G-D-I-V-I-A-E-I-D-G-E-F-T-V-K-R-L-L-L-R-P-R-P-A-L-E-P-V-S-D-S-P-E-F-R-T-L-Y-P-E-N-I-C-I-F-G-V-V-T-H-V-I-H-R-T-R-E-L-R"} +{"text": "### FUNCTION This protein is involved in the determination of copy number in gene replication It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA ### SEQUENCE -M-S-Q-T-E-N-A-V-T-S-S-S-G-A-K-R-A-Y-R-K-G-N-P-L-S-D-A-E-K-Q-R-L-S-V-A-R-K-R-A-S-F-K-E-V-K-V-F-L-E-P-K-Y-K-A-M-L-M-Q-M-C-H-E-D-G-L-T-Q-A-E-V-L-T-A-L-I-K-S-E-A-Q-K-R-C-V"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-S-K-E-Q-K-T-P-E-G-Q-A-P-E-E-I-I-M-D-Q-H-E-E-I-E-A-V-E-P-E-A-S-A-E-Q-V-D-P-R-D-E-K-I-A-N-L-E-A-Q-L-A-E-A-Q-T-R-E-R-D-G-I-L-R-V-K-A-E-M-E-N-L-R-R-R-T-E-L-D-I-E-K-A-H-K-F-A-L-E-K-F-I-N-E-L-L-P-V-I-D-S-L-D-R-A-L-E-V-A-D-K-A-N-P-D-M-S-A-M-V-E-G-I-E-L-T-L-K-S-M-L-D-V-V-R-K-F-G-V-E-V-I-A-E-T-N-V-P-L-D-P-N-V-H-Q-A-I-A-M-V-E-S-D-D-V-A-P-G-N-V-L-G-I-M-Q-K-G-Y-T-L-N-G-R-T-I-R-A-A-M-V-T-V-A-K-A-K-A"} +{"text": "### FUNCTION Participates in cysteine desulfuration mediated by SufS Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process ### SEQUENCE -M-A-L-L-P-D-K-E-K-L-L-R-N-F-L-R-C-A-N-W-E-E-K-Y-L-Y-I-I-E-L-G-Q-R-L-P-E-L-R-A-E-D-G-S-P-Q-N-S-I-Q-G-C-Q-S-Q-V-W-I-V-M-R-Q-N-A-Q-G-I-I-E-L-Q-G-D-S-D-A-A-I-V-K-G-L-I-A-V-V-F-I-L-Y-D-Q-M-T-P-Q-D-I-V-N-F-D-V-R-P-W-F-E-K-M-A-L-T-Q-H-L-T-P-S-R-S-Q-G-L-E-A-M-I-R-A-I-R-A-K-A-A-A-L-S"} +{"text": "### FUNCTION The VirB system could be required for the establishment of the replication niche in the host ### SEQUENCE -M-K-T-A-S-P-S-K-K-S-L-S-R-I-L-P-H-L-L-L-A-L-I-V-S-I-A-A-I-E-P-N-L-A-H-A-N-G-G-L-D-K-V-N-T-S-M-Q-K-V-L-D-L-L-S-G-V-S-I-T-I-V-T-I-A-I-I-W-S-G-Y-K-M-A-F-R-H-A-R-F-M-D-V-V-P-V-L-G-G-A-L-V-V-G-A-A-A-E-I-A-S-Y-L-L-R"} +{"text": "### FUNCTION The VirB system could be required for the establishment of the replication niche in the host ### SEQUENCE -M-T-T-A-P-Q-E-S-N-A-R-S-A-G-Y-R-G-D-P-I-F-K-G-C-T-R-P-A-M-L-F-G-V-P-V-I-P-L-V-I-V-G-G-S-I-V-L-L-S-V-W-I-S-M-F-I-L-P-L-I-V-P-I-V-L-V-M-R-Q-I-T-Q-T-D-D-Q-M-F-R-L-L-G-L-K-A-Q-F-R-L-I-H-F-N-R-T-G-R-F-W-R-A-S-A-Y-S-P-I-A-F-T-K-R-K-R-E-S"} +{"text": "### FUNCTION The VirB system could be required for the establishment of the replication niche in the host ### SEQUENCE -M-K-K-V-I-L-A-F-V-A-T-A-F-L-A-G-C-T-T-T-G-P-A-V-V-P-V-L-D-G-K-P-R-V-P-V-N-K-S-V-P-A-K-P-P-L-A-Q-P-N-P-V-D-T-Y-E-D"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-L-N-A-T-I-L-G-Q-A-I-A-F-V-L-F-V-I-F-C-M-K-Y-V-W-P-P-I-M-A-A-I-E-K-R-Q-Q-E-I-A-D-G-L-S-S-A-E-R-A-K-K-D-L-D-L-A-Q-A-N-A-T-D-Q-L-K-K-A-K-A-E-A-Q-V-I-I-E-Q-A-S-K-R-K-A-Q-I-L-D-E-A-K-A-E-A-E-Q-E-R-N-K-I-V-A-Q-A-Q-A-E-I-D-A-E-R-K-R-A-R-E-E-L-R-K-Q-V-A-M-L-A-I-A-G-A-E-K-I-I-E-R-S-V-D-E-A-A-N-S-D-I-V-D-K-L-V-A-E-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-E-F-V-T-V-A-R-P-Y-A-K-A-A-F-D-F-A-V-E-H-Q-A-V-E-R-W-Q-N-M-L-A-F-T-A-Q-V-T-R-N-E-Q-I-A-E-L-L-S-G-A-V-A-P-E-T-M-S-T-T-F-I-A-V-C-G-D-Q-L-D-E-P-A-Q-N-F-I-R-V-M-A-E-N-G-R-L-L-V-L-P-E-V-L-Q-Q-F-I-Q-L-R-A-S-L-E-S-T-V-D-V-E-V-S-S-A-R-A-L-N-D-E-Q-L-A-K-I-A-A-A-M-E-K-R-L-S-R-K-V-K-L-N-C-K-I-D-K-S-V-M-A-G-V-V-I-R-A-G-D-M-V-I-D-G-S-V-R-G-R-L-E-R-L-A-D-V-L-Q-S"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-V-I-P-A-G-V-E-V-K-L-N-G-Q-V-I-S-I-K-G-K-N-G-E-L-T-R-T-V-H-S-A-V-E-V-K-Q-E-E-N-T-L-T-F-A-P-R-E-G-A-V-D-G-W-A-Q-A-G-T-T-R-A-L-L-N-S-M-V-I-G-V-T-E-G-F-T-K-K-L-Q-L-V-G-V-G-Y-R-A-A-V-K-G-N-V-V-N-L-A-L-G-F-S-H-P-V-D-H-E-L-P-A-G-I-T-A-E-C-P-T-Q-T-E-I-V-L-K-G-A-D-K-Q-V-I-G-Q-V-A-A-D-L-R-A-Y-R-R-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-V-V-R-T-K-E-A-K-K-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-E-Q-T-M-L-N-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-G-I-G-D-I-I-K-I-T-I-K-E-A-I-P-R-G-K-V-K-K-G-D-V-L-K-A-V-V-V-R-T-K-K-G-V-R-R-P-D-G-S-V-I-R-F-D-G-N-A-C-V-I-L-N-N-N-S-E-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-N-E-K-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION May function as a transcriptional regulator that controls feoABC expression ### SEQUENCE -M-A-S-L-L-Q-L-R-D-A-I-A-L-N-G-S-A-E-A-S-Q-L-S-R-Q-L-A-I-P-L-P-L-V-N-A-M-L-E-K-L-T-A-M-G-K-I-E-R-I-E-L-D-H-S-G-C-L-T-G-S-C-K-S-C-P-E-G-H-Q-H-C-N-T-V-I-Y-Q-L-K-E-P-H-A-H-Q"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-I-G-N-E-R-H-G-L-V-G-V-I-G-A-D-L-I-R-N-A-K-I-P-L-I-L-L-V-A-V-L-I-S-A-V-L-V-V-T-T-A-H-R-T-R-L-L-T-A-E-R-E-Q-L-V-L-E-R-D-A-L-D-I-E-W-R-N-L-I-L-E-E-N-A-L-G-D-H-S-R-V-E-S-I-A-I-E-K-L-K-M-Q-H-V-D-P-S-Q-E-N-I-V-I-K"} +{"text": "### FUNCTION Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ### SEQUENCE -M-I-T-M-R-C-K-M-L-T-A-A-A-V-M-L-A-M-L-T-A-G-C-S-T-L-E-K-V-V-Y-R-P-D-I-N-Q-G-N-Y-L-S-P-I-D-A-S-K-I-H-K-G-M-T-Q-Q-Q-V-A-Y-T-L-G-T-P-M-L-Q-D-P-F-G-T-Q-T-W-F-Y-V-F-R-Q-Q-P-G-H-E-K-I-T-Q-Q-T-L-T-L-T-F-D-S-S-G-V-L-T-D-I-K-N-E-P-A-L-T-G-S"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-S-K-E-Q-K-T-P-N-E-Q-V-S-E-E-M-E-N-T-A-E-Q-Q-V-E-A-T-Q-E-T-G-E-C-V-D-P-R-V-A-E-L-E-V-Q-L-S-D-A-L-Q-R-E-R-E-S-L-L-R-A-K-A-E-V-E-N-I-R-R-R-T-E-L-D-V-E-K-A-H-K-F-A-L-E-R-F-S-S-E-L-L-P-V-I-D-N-L-E-R-A-L-D-T-A-D-K-T-N-T-E-L-I-S-M-I-E-G-V-E-L-T-L-K-S-L-L-D-A-V-G-K-F-G-I-E-V-V-G-E-T-H-V-P-F-N-P-E-V-H-Q-A-M-T-M-L-E-S-A-D-H-E-P-N-H-V-M-M-V-M-Q-K-G-Y-T-L-N-G-R-L-L-R-P-A-M-V-A-V-S-K-A-K-S"} +{"text": "### FUNCTION Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ ### SEQUENCE -M-R-I-K-P-D-D-K-W-R-W-Y-F-D-T-E-H-D-R-L-M-L-D-L-A-N-G-M-I-F-R-S-R-F-P-S-K-M-L-T-P-D-A-F-D-E-S-A-F-C-V-D-D-A-A-L-Y-F-E-F-E-D-Q-C-R-Q-I-K-L-S-N-E-Q-R-S-E-L-V-L-N-A-L-V-A-C-R-F-L-K-P-L-M-P-K-S-W-H-F-V-Q-Q-P-K-V-L-I-P-Q-N-G-E-L-T-L-V-T-V-L-D-N-G-E-N-V-R-L-L-V-V-E-P-S-C-S-A-S-L-C-L-L-A-Q-S-Q-V-V-L-A-G-R-Q-L-V-L-G-D-A-I-K-I-M-N-N-R-L-L-P-L-M-V-E-E-V-N-T-T-T-A-Y-D-R-A-V"} +{"text": "### FUNCTION Component of the SOS system and an inhibitor of cell division Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments In the presence of GTP, binds a polymerization-competent form of FtsZ in a 11 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division ### SEQUENCE -M-R-T-Q-S-L-K-P-Y-H-A-N-Y-H-S-L-T-T-N-D-S-P-T-R-V-D-A-P-T-D-S-G-L-I-S-E-F-V-Y-S-E-N-Q-P-V-V-T-Q-L-L-L-P-L-L-Q-Q-L-S-K-Q-S-R-W-L-L-W-L-T-P-Q-Q-K-L-S-R-S-W-L-K-Q-S-G-L-P-I-N-K-V-V-Q-L-R-Q-I-N-P-L-S-T-V-E-A-M-E-K-A-L-L-T-G-N-Y-S-V-V-L-G-W-L-P-E-L-T-E-D-D-R-I-R-L-R-L-A-A-K-L-G-N-A-Y-G-F-V-M-R-P-L-N-D-T-K-V-G-S-G-Q-C-A-T-L-K-I-H-S-Y-L-Y-H"} +{"text": "### FUNCTION Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress ### SEQUENCE -M-I-A-S-K-F-G-I-G-Q-Q-V-R-H-S-L-H-G-Y-L-G-V-V-I-D-I-D-P-E-Y-S-L-A-P-P-E-P-D-E-V-A-N-N-K-T-L-R-S-S-P-W-Y-H-V-V-I-E-D-D-D-G-Q-P-V-H-T-Y-L-A-E-A-Q-L-T-Y-E-D-V-D-A-H-P-E-Q-P-S-L-D-E-L-A-A-S-I-R-H-Q-L-Q-A-P-H-L-R-N"} +{"text": "### FUNCTION Probably mediates the hydrolysis of some nucleoside diphosphate derivatives ### SEQUENCE -M-S-E-L-I-T-G-Q-Y-L-S-E-F-I-N-R-F-Q-L-Q-L-P-Q-P-D-N-V-L-T-H-S-H-Y-F-S-A-T-N-R-R-A-A-V-L-I-P-I-I-C-R-P-E-P-T-L-L-L-T-R-R-A-D-H-L-R-K-H-A-G-Q-V-A-F-P-G-G-K-A-D-P-D-D-Q-S-L-I-S-T-A-L-R-E-A-E-E-E-V-A-I-P-A-S-V-V-H-V-L-G-K-L-A-P-L-N-S-S-S-G-Y-H-V-T-P-I-V-G-L-V-P-A-N-I-P-F-Y-G-N-D-E-E-V-A-G-L-F-E-I-P-L-H-E-A-L-S-L-S-R-Y-H-S-L-D-I-H-R-E-G-I-N-H-R-V-Y-L-S-W-Y-E-N-Q-F-I-W-G-L-T-A-T-I-I-R-H-L-A-Q-Q-V-S-I"} +{"text": "### FUNCTION Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B ### SEQUENCE -M-K-R-Y-L-S-L-A-L-A-A-L-V-L-T-G-C-V-P-P-D-S-V-T-P-T-P-P-V-T-I-E-P-V-T-P-P-D-V-E-V-P-P-P-V-D-T-V-P-Q-P-P-K-V-Q-S-I-D-W-A-V-S-V-E-P-L-V-A-Q-M-V-N-S-D-E-V-A-T-G-S-I-L-L-V-D-S-V-K-N-N-T-N-G-A-L-Q-T-A-K-A-T-A-A-L-H-Q-V-L-S-S-N-K-K-F-V-L-I-S-P-Q-Q-L-G-V-A-K-Q-T-L-G-L-S-E-E-D-S-F-G-S-R-S-K-A-I-G-L-A-R-Y-V-G-A-Q-Y-V-L-Y-S-D-V-S-G-D-V-K-S-P-T-I-E-M-Q-L-M-Q-T-Q-T-G-E-I-I-W-S-G-N-A-P-V-Q-Y"} +{"text": "### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-T-L-T-S-A-H-P-K-S-K-L-M-K-R-F-A-A-L-G-P-Y-L-R-E-G-Q-C-Q-N-D-H-F-F-F-D-C-L-A-V-C-I-N-V-K-L-A-P-E-K-R-E-F-W-G-W-W-I-E-L-E-P-S-A-G-R-F-T-Y-V-Y-Q-L-G-L-F-N-K-E-G-N-W-N-A-E-K-I-S-D-P-E-V-Q-D-K-L-E-S-T-L-R-S-F-H-L-R-L-E-E-M-L-A-S-I-D-M-K-L-E-P-A-A-D-F-N-D-Q-P-V-K-L-S-A"} +{"text": "### FUNCTION Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase ### SEQUENCE -M-L-N-R-L-E-S-L-T-Q-R-V-G-G-S-N-E-L-I-D-Q-W-L-H-A-R-K-E-L-L-V-S-Y-C-T-V-I-G-I-K-P-Q-K-E-K-H-T-P-L-N-A-K-T-L-E-N-F-C-H-N-L-V-D-Y-L-S-S-G-H-F-H-L-Y-D-R-I-I-K-E-V-E-G-A-S-S-P-K-M-A-L-T-A-K-I-H-P-A-L-K-N-N-T-Q-T-I-M-A-F-H-D-C-Y-T-N-I-E-I-D-D-D-S-C-T-E-Y-Q-Q-A-L-S-D-I-G-E-A-L-D-A-R-F-R-L-E-D-Q-L-I-Q-W-A-A-E-S-W-Q-A-A-Q-L-A-D-A-D-K-K-S-Q-V-N"} +{"text": "### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-F-E-V-F-E-K-L-E-V-K-V-Q-Q-A-I-D-T-I-T-L-L-Q-M-E-I-E-E-L-K-E-K-N-N-T-L-T-Q-E-V-Q-D-A-A-G-S-R-E-A-L-V-R-E-N-E-Q-L-K-Q-E-Q-H-V-W-Q-D-R-L-R-A-L-L-G-K-M-E-E-V"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-S-M-I-H-R-D-I-K-R-A-K-L-A-K-K-F-A-G-K-R-D-A-L-K-K-I-L-S-S-Q-D-A-S-Y-E-E-K-I-D-A-S-T-K-L-Q-K-L-P-R-D-S-S-P-S-R-H-R-N-R-C-E-L-S-G-R-P-R-G-V-Y-R-K-F-G-L-G-R-N-M-L-R-K-A-T-M-N-G-D-V-P-G-L-R-K-A-S-W"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-Y-L-D-V-A-D-N-S-G-A-K-E-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-H-I-G-D-I-I-K-V-T-V-K-D-A-I-P-R-G-K-V-K-K-G-E-V-Y-D-A-V-V-V-R-T-R-K-G-V-R-R-P-D-G-S-L-I-R-F-D-G-N-A-A-V-L-L-N-N-K-Q-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-S-E-K-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-T-M-E-A-K-A-I-L-R-T-A-R-I-S-P-Q-K-A-R-L-V-A-D-Q-V-R-G-L-S-A-E-R-A-V-N-L-L-K-F-S-D-K-K-A-A-H-L-I-K-K-V-V-E-S-A-I-A-N-A-E-N-N-Q-G-A-D-V-D-E-L-K-V-K-T-I-M-V-D-E-G-P-S-L-K-R-F-M-A-R-A-K-G-R-G-T-R-I-L-K-R-T-S-H-I-T-V-V-V-G-A-A-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-T-T-F-T-A-K-S-E-T-V-Q-R-D-W-Y-L-V-D-A-A-G-K-T-L-G-R-L-S-T-E-L-A-R-R-L-R-G-K-H-K-P-V-Y-T-P-H-V-D-T-G-D-Y-L-V-V-I-N-A-E-K-I-V-V-T-G-N-K-L-K-D-K-K-Y-H-R-F-T-G-Y-I-G-N-L-K-T-E-S-L-E-Q-A-L-Q-R-H-P-E-R-V-I-E-I-A-V-K-G-M-L-P-K-G-P-L-G-R-T-M-Y-R-K-L-K-V-Y-S-G-A-E-H-P-H-A-A-Q-Q-P-Q-V-L-D-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-N-E-I-I-A-Q-Y-A-R-H-E-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-W-E-I-N-H-L-N-S-H-I-K-E-H-K-K-D-H-A-T-Y-R-G-L-M-K-K-I-G-H-R-R-N-L-L-A-Y-L-R-R-T-D-V-N-R-Y-R-E-L-I-Q-S-L-G-L-R-R"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-F-Y-Q-E-T-K-D-Q-S-P-R-R-E-S-T-K-A-L-Y-L-N-I-D-A-T-D-E-L-D-G-R-I-K-A-R-R-L-V-E-D-N-T-Y-Y-N-V-E-F-I-E-L-L-S-D-K-H-L-D-Y-E-K-E-T-G-V-F-E-L-T-E-F"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-T-S-I-I-Y-S-P-K-D-I-F-E-Q-E-F-K-T-S-M-R-G-F-D-K-K-E-V-D-E-F-L-D-N-V-I-K-D-Y-E-N-F-N-A-Q-I-E-A-L-K-A-E-N-E-A-L-K-K-A-K-F-Q-A-R-N-T-V-S-A-T-V-Q-Q-P-V-P-Q-P-T-R-V-A-Q-S-A-T-N-F-D-I-L-K-R-I-S-K-L-E-K-E-V-F-G-K-Q-I-I-E"} +{"text": "### FUNCTION Regulates the transcription of the arc operon, involved in arginine catabolism ### SEQUENCE -M-N-K-K-E-T-R-H-Q-L-I-R-S-L-I-S-E-T-T-I-H-T-Q-Q-E-L-Q-E-R-L-Q-K-N-G-I-T-I-T-Q-A-T-L-S-R-D-M-K-E-L-N-L-V-K-V-T-S-G-N-D-T-H-Y-E-A-L-A-I-S-Q-T-R-W-E-H-R-L-R-F-Y-M-E-D-A-L-V-M-L-K-I-V-Q-H-Q-I-I-L-K-T-L-P-G-L-A-Q-S-F-G-S-I-L-D-A-M-Q-I-P-E-I-V-A-T-V-C-G-D-D-T-C-L-I-V-C-E-D-N-E-Q-A-K-A-C-Y-E-T-L-S-H-Y-T-P-P-F-F-F-S-N-K"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-T-Y-A-I-I-K-T-G-G-K-Q-V-K-V-E-V-G-Q-A-I-Y-V-E-K-I-D-A-E-A-G-A-E-V-T-F-N-E-V-V-L-V-G-G-D-K-T-V-V-G-T-P-V-V-E-G-A-T-V-V-G-T-V-E-K-Q-G-K-Q-K-K-V-V-T-F-K-Y-K-P-K-K-G-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-N-A-I-N-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-A-A-E-G-S-R-K-V-R-N-R-V-G-R-G-T-S-S-G-N-G-K-T-S-G-R-G-Q-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-I-P-K-R-G-F-T-N-I-N-T-K-E-Y-A-L-V-N-L-D-Q-L-N-V-F-D-D-G-T-E-V-T-P-A-I-L-K-D-A-G-I-V-R-A-E-K-S-G-V-K-V-L-G-N-G-E-L-T-K-K-L-T-V-K-A-A-K-F-S-K-S-A-E-A-A-I-I-A-K-G-G-S-I-E-V-I"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-I-R-Q-K-R-H-R-R-V-R-G-K-L-S-G-T-A-D-R-P-R-L-N-V-F-R-S-N-T-G-I-Y-A-Q-V-I-D-D-V-A-G-V-T-L-A-S-A-S-T-L-D-K-D-V-S-K-G-T-K-T-E-Q-A-V-V-V-G-K-L-V-A-E-R-A-V-A-K-G-I-S-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-N-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-V-I-T-M-P-A-G-V-E-L-T-N-N-N-N-V-I-T-V-K-G-P-K-G-E-L-T-R-E-F-N-K-N-I-E-I-K-V-E-G-T-E-I-T-V-V-R-P-N-D-S-K-E-M-K-T-I-H-G-T-T-R-A-N-L-N-N-M-V-V-G-V-S-E-G-F-K-K-D-L-E-M-K-G-V-G-Y-R-A-Q-L-Q-G-T-K-L-V-L-S-V-G-K-S-H-Q-D-E-V-E-A-P-E-G-I-T-F-T-V-A-N-P-T-S-I-S-V-E-G-I-N-K-E-V-V-G-Q-T-A-A-Y-I-R-S-L-R-S-P-E-P-Y-K-G-K-G-I-R-Y-V-G-E-Y-V-R-L-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-N-R-L-K-E-K-Y-T-N-E-V-I-P-A-L-T-E-K-F-N-Y-T-S-V-M-A-V-P-K-V-E-K-I-V-L-N-M-G-V-G-D-A-V-S-N-A-K-N-L-E-K-A-A-A-E-L-A-L-I-S-G-Q-K-P-L-I-T-K-A-K-K-S-I-A-G-F-R-L-R-E-G-V-A-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-V-S-V-S-L-P-R-V-R-D-F-H-G-V-P-T-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-S-F-D-D-V-D-K-V-R-G-L-D-I-V-I-V-T-T-A-N-T-D-E-E-S-R-E-L-L-K-G-L-G-M-P-F-A-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-K-V-A-D-N-S-G-A-R-E-I-L-T-I-K-V-L-G-G-S-G-R-K-F-A-N-I-G-D-V-I-V-A-S-V-K-Q-A-T-P-G-G-A-V-K-K-G-D-V-V-K-A-V-I-V-R-T-K-T-G-A-R-R-P-D-G-S-Y-I-K-F-D-D-N-A-A-V-I-I-R-D-D-K-T-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-G-Y-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-N-Q-R-K-T-L-Y-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-K-R-N-H-P-V-Y-G-K-R-I-N-Y-S-K-K-Y-K-A-H-D-E-N-N-V-A-K-E-G-D-I-V-R-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-V-V-E-K-A-V-I-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-H-R-R-E-F-R-G-K-M-R-G-E-A-K-G-G-K-E-V-S-F-G-E-Y-G-L-Q-A-T-T-S-H-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-A-K-A-I-G-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-P-V-K-R-G-K-V-M-F-E-I-A-G-V-S-E-E-I-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-C-K-F-V-K-R-E-A-E"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-E-I-T-S-A-K-A-M-A-R-T-V-R-V-S-P-R-K-T-R-L-V-L-D-L-I-R-G-K-K-V-A-D-A-I-A-I-L-K-F-T-P-N-K-A-A-R-V-I-E-K-T-L-N-S-A-I-A-N-A-E-N-N-F-G-L-E-K-A-N-L-V-V-S-E-T-F-A-N-E-G-P-T-M-K-R-F-R-P-R-A-K-G-S-A-S-P-I-N-K-R-T-T-H-V-T-V-V-V-S-E-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-L-Y-D-V-I-K-K-P-V-I-T-E-K-S-M-I-A-L-E-A-G-K-Y-T-F-E-V-D-T-R-A-H-K-L-L-I-K-Q-A-V-E-A-A-F-D-G-V-K-V-A-S-V-N-T-V-N-V-K-P-K-A-K-R-V-G-R-Y-T-G-F-T-S-K-T-K-K-A-I-I-T-L-T-A-D-S-K-A-I-E-L-F-A-A-E-A-E"} +{"text": "### FUNCTION Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose Essential for virulence May be involved in LPS biosynthesis or polysaccharide transport ### SEQUENCE -M-N-S-F-R-K-T-C-A-G-A-L-A-L-I-F-G-A-T-S-I-V-P-T-V-A-A-P-M-N-M-D-R-P-A-I-N-Q-N-V-I-Q-A-R-A-H-Y-R-P-Q-N-Y-N-R-G-H-R-P-G-Y-W-H-G-H-R-G-Y-R-H-Y-R-H-G-Y-R-R-H-N-D-G-W-W-Y-P-L-A-A-F-G-A-G-A-I-I-G-G-A-I-S-Q-P-R-P-V-Y-R-A-P-A-G-S-P-H-V-Q-W-C-Y-S-R-Y-K-S-Y-R-A-S-D-N-T-F-Q-P-Y-N-G-P-R-K-Q-C-R-S-P-Y-S-R"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-F-R-A-I-A-I-I-R-A-H-E-V-I-D-A-V-P-A-S-H-I-V-L-E-R-D-E-R-H-L-R-R-K-A-I-T-L-E-N-G-E-K-I-L-A-D-F-A-E-P-V-V-L-E-H-G-D-R-L-V-L-D-D-G-R-E-I-E-I-R-A-A-S-E-E-L-Y-E-I-R-G-R-D-P-R-H-I-A-E-L-A-W-H-I-G-N-R-H-L-A-A-Q-I-E-T-D-H-I-F-I-L-R-D-H-V-I-R-V-M-L-E-G-L-G-A-T-V-T-D-V-V-A-I-F-S-P-L-R-G-A-Y-S-G-G-H-Q-H-H-H-G-H-D-H-D-H-G-H-H-G-H-D-H-D-H-H-H-P-D-H-E"} +{"text": "### FUNCTION Guanidinium ion exporter Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons ### SEQUENCE -M-S-W-I-I-L-L-I-A-G-L-L-E-V-V-W-A-V-G-L-K-Y-T-H-G-F-S-R-L-T-P-S-I-I-T-I-T-A-M-V-I-S-M-A-L-L-S-W-A-M-K-T-L-P-V-G-T-A-Y-A-I-W-T-G-I-G-A-V-G-A-A-I-T-G-I-L-L-L-G-E-S-A-S-P-A-R-L-L-S-L-G-L-I-V-A-G-I-I-G-L-K-L-S-A-H"} +{"text": "### FUNCTION Involved in resistance toward heavy metals ### SEQUENCE -M-L-D-V-K-S-Q-D-I-S-I-P-E-A-V-V-V-L-C-T-A-P-D-E-A-T-A-Q-D-L-A-A-K-V-L-A-E-K-L-A-A-C-A-T-L-L-P-G-A-T-S-L-Y-Y-W-E-G-K-L-E-Q-E-Y-E-V-Q-M-I-L-K-T-T-V-S-H-Q-Q-A-L-I-D-C-L-K-S-H-H-P-Y-Q-T-P-E-L-L-V-L-P-V-T-H-G-D-T-D-Y-L-S-W-L-N-A-S-L-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-L-N-A-T-I-L-G-Q-A-I-A-F-I-L-F-V-W-F-C-M-K-Y-V-W-P-P-L-M-A-A-I-E-K-R-Q-K-E-I-A-D-G-L-A-S-A-E-R-A-H-K-D-L-D-L-A-K-A-S-A-T-D-Q-L-K-K-A-K-A-E-A-Q-V-I-I-E-Q-A-N-K-R-R-A-Q-I-L-D-E-A-K-T-E-A-E-Q-E-R-T-K-I-V-A-Q-A-Q-A-E-I-E-A-E-R-K-R-A-R-E-E-L-R-K-Q-V-A-I-L-A-V-A-G-A-E-K-I-I-E-R-S-V-D-E-A-A-N-S-D-I-V-D-K-L-V-A-E-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-E-F-V-T-V-A-R-P-Y-A-K-A-A-F-D-F-A-V-E-H-Q-S-V-E-R-W-Q-D-M-L-A-F-A-A-E-V-T-K-N-E-Q-M-A-E-L-L-S-G-A-L-A-P-E-T-L-A-E-S-F-I-A-V-C-G-E-Q-L-D-E-N-G-Q-N-L-I-R-V-M-A-E-N-N-R-L-N-A-L-P-D-V-L-E-Q-F-I-H-L-R-A-A-S-E-A-T-S-E-V-E-V-T-S-A-T-A-L-S-E-E-Q-L-S-K-I-S-A-A-M-E-K-R-L-S-R-K-V-K-L-N-C-K-I-D-K-S-V-M-A-G-V-I-I-R-A-G-D-M-V-I-D-G-S-V-R-G-R-L-E-R-L-A-D-V-L-Q-S"} +{"text": "### FUNCTION Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE Its activity is ATP-independent ### SEQUENCE -M-R-N-F-D-L-S-P-L-Y-R-S-A-I-G-F-D-R-L-F-N-L-L-E-N-N-Q-S-Q-S-N-G-G-Y-P-P-Y-N-V-E-L-V-D-E-N-H-Y-R-I-A-I-A-V-A-G-F-A-E-S-E-L-E-I-T-A-Q-D-N-L-L-V-V-K-G-A-H-A-D-E-Q-K-E-R-T-Y-L-Y-Q-G-I-A-E-R-N-F-E-R-K-F-Q-L-A-E-N-I-H-V-R-G-A-N-L-V-N-G-L-L-Y-I-E-L-E-R-V-I-P-E-A-N-K-P-R-R-I-E-I-N"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-E-Q-N-N-T-E-M-A-F-Q-I-Q-R-I-Y-T-K-D-V-S-F-E-A-P-N-A-P-H-V-F-Q-K-D-W-Q-P-E-V-K-L-D-L-D-T-A-S-S-Q-L-A-D-D-V-Y-E-V-V-L-R-V-T-V-T-A-S-L-G-E-E-T-A-F-L-C-E-V-Q-Q-A-G-I-F-S-I-S-G-I-E-G-T-Q-M-A-H-C-L-G-A-Y-C-P-N-I-L-F-P-Y-A-R-E-C-I-T-S-L-V-S-R-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-M-N-Y-L-Q-Q-Q-A-G-E-G-T-E-E-H-Q-D-A"} +{"text": "### FUNCTION Required for cellulose biosynthesis ### SEQUENCE -M-M-T-I-S-D-I-V-Q-I-I-L-F-C-A-L-I-F-F-P-L-G-Y-L-A-R-H-S-L-R-R-I-S-D-T-T-R-L-L-F-A-K-P-R-Y-V-K-P-A-G-T-L-R-R-A-T-K-V-K-A-D-K-K"} +{"text": "### FUNCTION May function as a transcriptional regulator that controls feoABC expression ### SEQUENCE -M-A-S-L-I-Q-V-R-D-L-L-A-L-R-G-R-M-E-A-T-Q-I-S-H-T-L-H-A-P-Q-P-M-I-D-A-M-L-N-Q-L-E-I-M-G-K-A-V-R-I-P-E-E-P-D-G-C-L-S-G-S-C-K-S-C-P-E-G-K-A-C-L-R-E-W-W-A-L-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-R-E-E-R-L-L-K-V-L-R-A-P-H-V-S-E-K-A-S-T-A-M-E-K-T-N-T-I-V-L-K-V-A-K-D-A-T-K-A-E-I-K-A-A-V-Q-K-L-F-E-V-E-V-E-V-V-N-T-L-V-V-K-G-K-V-K-R-H-G-Q-R-I-G-R-R-S-D-W-K-K-A-Y-V-T-L-K-E-G-Q-N-L-D-F-V-G-G-A-E"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-M-H-K-G-R-N-R-G-L-A-A-G-A-D-V-S-F-G-S-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-A-V-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-A-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-V-L-Y-E-M-D-G-V-P-E-E-L-A-R-E-A-F-K-L-A-A-A-K-L-P-I-K-T-T-F-V-T-K-T-V-M"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-E-Q-T-M-L-N-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-G-V-G-D-I-I-K-I-T-I-K-E-A-I-P-R-G-K-V-K-K-G-D-V-L-K-A-V-V-V-R-T-K-K-G-V-R-R-P-D-G-S-V-I-R-F-D-G-N-A-C-V-I-L-N-N-N-S-E-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-N-E-K-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-S-A-R-I-R-R-A-T-R-A-R-R-K-L-K-E-L-G-A-T-R-L-V-V-H-R-T-P-R-H-I-Y-A-Q-V-I-A-P-N-G-S-E-V-L-V-A-A-S-T-V-E-K-A-I-A-E-Q-L-K-Y-T-G-N-K-D-A-A-A-A-V-G-K-A-V-A-E-R-A-L-E-K-G-I-K-D-V-S-F-D-R-S-G-F-Q-Y-H-G-R-V-Q-A-L-A-D-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-S-E-G-Q-T-V-R-L-E-K-L-D-I-A-T-G-E-T-I-E-F-A-E-V-L-M-I-A-N-G-E-E-V-K-I-G-V-P-F-V-D-G-G-V-I-K-A-E-V-V-A-H-G-R-G-E-K-V-K-I-V-K-F-R-R-R-K-H-Y-R-K-Q-Q-G-H-R-Q-W-F-T-D-V-K-I-T-G-I-S-A"} +{"text": "### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-S-A-Q-P-V-D-I-Q-I-F-G-R-S-L-R-V-N-C-P-P-D-Q-R-D-A-L-N-Q-A-A-D-D-L-N-Q-R-L-Q-D-L-K-V-R-T-R-V-T-N-T-E-Q-L-V-F-I-A-A-L-N-I-S-Y-E-L-T-Q-E-K-A-K-T-R-D-Y-A-A-S-M-E-Q-R-I-R-M-L-Q-Q-T-I-E-Q-A-L-L-D-Q-G-R-I-T-E-K-T-G-Q-N-F-E"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-D-I-H-N-K-A-R-I-H-W-A-C-R-R-G-M-R-E-L-D-I-S-I-M-P-F-F-E-H-E-Y-D-S-L-S-D-E-E-K-R-I-F-V-R-L-L-Q-S-D-D-P-D-L-F-N-W-L-M-N-H-G-K-P-A-D-A-E-L-E-Q-M-V-R-L-I-Q-T-R-N-R-E-R-G-P-V-A-I"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Upon expression in Ecoli neutralizes the effect of cognate toxin VapC ### SEQUENCE -M-H-T-T-L-F-F-S-N-R-T-Q-A-V-R-L-P-K-S-I-S-F-P-E-D-V-K-H-V-E-I-I-A-V-G-R-S-R-I-I-T-P-V-G-E-S-W-D-S-W-F-D-G-E-G-A-S-T-D-F-M-S-T-R-E-Q-P-A-V-Q-E-R-E-G-F"} +{"text": "### FUNCTION Repressor of rcnA expression Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt In the presence of one of these metals, it has a weaker affinity for rcnA promoter ### SEQUENCE -M-S-H-T-I-R-D-K-Q-K-L-K-A-R-T-S-K-I-Q-G-Q-V-I-A-L-K-K-M-L-D-E-P-H-E-C-A-A-V-L-Q-Q-I-A-A-I-R-G-A-V-N-G-L-M-R-E-V-I-K-G-H-L-T-E-H-I-V-H-Q-S-D-E-A-R-R-E-E-D-L-D-V-I-L-K-V-L-D-S-Y-I-K"} +{"text": "### FUNCTION Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ### SEQUENCE -M-R-C-K-T-L-T-A-A-A-A-V-L-L-M-L-T-A-G-C-S-T-L-E-R-V-V-Y-R-P-D-I-N-Q-G-N-Y-L-T-P-T-D-V-A-K-V-R-V-G-M-T-Q-Q-Q-V-A-Y-A-L-G-T-P-M-M-T-D-P-F-G-T-N-T-W-F-Y-V-F-R-Q-Q-P-G-H-E-N-V-T-Q-Q-T-L-T-L-T-F-N-S-S-G-V-L-T-N-I-D-N-K-P-A-L-T-K"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-S-K-E-Q-K-T-P-E-G-Q-A-P-E-E-I-I-M-D-Q-H-E-E-V-E-A-V-E-P-N-D-S-A-E-Q-V-D-P-R-D-E-K-I-A-N-L-E-V-Q-L-A-E-A-Q-T-R-E-R-D-T-V-L-R-I-K-A-E-M-E-N-L-R-R-R-T-E-Q-D-I-E-K-A-H-K-F-A-L-E-K-F-V-N-E-L-L-P-V-I-D-S-L-D-R-A-L-E-V-A-D-K-A-N-P-D-M-A-A-M-V-E-G-I-E-L-T-L-K-S-M-L-D-V-V-R-K-F-G-V-E-V-I-A-E-T-N-V-P-L-D-P-N-V-H-Q-A-I-A-M-V-E-S-E-E-V-P-A-G-N-V-L-G-I-M-Q-K-G-Y-T-L-N-G-R-T-I-R-A-A-M-V-T-V-A-K-A-K"} +{"text": "### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-T-G-I-Q-I-T-K-A-A-N-D-D-L-L-N-S-F-W-L-L-D-S-E-K-G-E-A-R-C-I-V-A-K-S-G-F-A-E-D-E-V-V-A-V-S-K-L-G-E-I-E-Y-R-E-I-P-M-E-V-K-P-E-V-R-V-E-G-G-Q-H-L-N-V-N-V-L-R-R-E-T-L-E-D-A-V-K-H-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-A-R-T-F-T-E-S-L"} +{"text": "### FUNCTION Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins ### SEQUENCE -M-R-L-T-S-K-G-R-Y-A-V-T-A-M-L-D-V-A-L-N-S-E-A-G-P-V-P-L-A-D-I-S-E-R-Q-G-I-S-L-S-Y-L-E-Q-L-F-S-R-L-R-K-N-G-L-V-S-S-V-R-G-P-G-G-G-Y-L-L-G-K-D-A-G-S-I-A-V-G-E-V-I-S-A-V-D-E-S-V-D-A-T-R-C-Q-G-K-G-G-C-Q-G-G-D-K-C-L-T-H-A-L-W-R-D-L-S-D-R-L-T-G-F-L-N-N-I-T-L-G-E-L-V-N-N-Q-E-V-L-D-V-S-G-R-Q-H-T-H-D-A-P-R-A-S-G-R-A-Q-D-A-I-D-V-K-L-R-A"} +{"text": "### FUNCTION Is able to transfer iron-sulfur clusters to apo-ferredoxin Multiple cycles of cluster formation and transfer are observed, suggesting that IscA acts catalytically Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB ### SEQUENCE -M-S-I-T-L-S-D-S-A-A-A-R-V-N-T-F-L-A-N-R-G-K-G-F-G-L-R-L-G-V-R-T-S-G-C-S-G-M-A-Y-V-L-E-F-V-D-E-P-T-A-E-D-T-V-F-E-D-K-G-V-K-V-V-V-D-G-K-S-L-Q-F-L-D-G-T-Q-L-D-F-V-K-E-G-L-N-E-G-F-K-F-S-N-P-N-V-K-D-E-C-G-C-G-E-S-F-H-V"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-F-T-I-N-A-E-V-R-K-E-Q-G-K-G-A-S-R-R-L-R-A-A-N-K-F-P-A-I-I-Y-G-G-S-E-A-P-I-A-I-E-L-D-H-D-Q-V-M-N-M-Q-A-K-A-E-F-Y-S-E-V-L-T-L-V-V-D-G-K-E-V-K-V-K-A-Q-A-V-Q-R-H-A-Y-K-P-K-L-T-H-I-D-F-V-R-A"} +{"text": "### FUNCTION PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP ### SEQUENCE -M-K-K-F-R-W-V-V-L-G-I-V-V-V-V-C-L-L-L-W-A-Q-V-F-N-I-M-C-D-Q-D-V-Q-F-F-S-G-I-C-A-I-N-K-F-I-P-W"} +{"text": "### FUNCTION Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein ### SEQUENCE -M-K-S-N-R-Q-A-R-H-I-L-G-L-D-Y-R-I-S-N-Q-R-K-V-V-T-E-G-D-T-S-S-V-V-N-N-P-T-G-R-K-R-R-A-D-S-Q-K"} +{"text": "### FUNCTION Binds to H-NS and modified the range of genes it silences ### SEQUENCE -M-T-V-Q-D-Y-L-L-K-F-R-K-I-S-S-L-E-S-L-E-K-L-F-D-H-L-N-Y-T-L-T-D-D-M-D-I-V-N-M-Y-R-A-A-D-H-R-R-A-E-L-V-S-G-G-R-L-F-D-V-G-Q-V-P-Q-S-V-W-R-Y-V-Q"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine ### SEQUENCE -M-L-I-F-E-G-K-E-I-S-T-D-S-E-G-Y-L-K-E-T-T-Q-W-S-E-A-L-A-V-A-I-A-A-N-E-G-I-E-L-S-A-E-H-W-E-V-V-R-F-V-R-E-F-Y-L-E-F-N-T-S-P-A-I-R-M-L-V-K-A-M-A-N-K-F-G-E-E-K-G-N-S-R-Y-L-Y-R-L-F-P-K-G-P-A-K-Q-A-T-K-I-A-G-L-P-K-P-V-K-C-I"} +{"text": "### FUNCTION Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress ### SEQUENCE -M-I-A-S-K-F-G-I-G-Q-Q-V-R-H-S-L-L-G-Y-L-G-V-V-V-D-I-D-P-E-Y-S-L-D-E-P-S-P-D-E-L-A-V-N-D-E-L-R-A-A-P-W-Y-H-V-V-M-E-D-D-D-G-Q-P-V-H-T-Y-L-A-E-A-Q-L-R-S-E-M-R-D-E-H-P-E-Q-P-S-M-D-E-L-A-R-T-I-R-K-Q-L-Q-A-P-R-L-R-N"} +{"text": "### FUNCTION Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins Repression is relieved when the region becomes fully methylated ### SEQUENCE -M-K-T-I-E-V-D-D-E-L-Y-S-Y-I-A-S-H-T-K-H-I-G-E-S-A-S-D-I-L-R-R-M-L-K-F-S-A-T-T-Q-P-T-A-S-A-V-K-G-T-P-A-A-Q-P-V-A-E-A-K-P-V-N-P-V-K-D-K-V-R-A-M-R-E-L-L-L-S-D-E-Y-A-E-Q-K-K-A-V-N-R-F-M-L-I-L-T-T-L-Y-S-L-D-H-H-A-F-A-E-A-T-E-S-L-H-G-R-T-R-V-Y-F-A-A-D-E-Q-T-L-L-K-N-G-N-Q-T-K-P-K-H-V-P-G-T-P-Y-W-V-I-T-N-T-N-T-G-R-K-C-S-M-I-E-H-I-M-Q-S-M-Q-F-P-A-E-L-I-E-K-V-C-G-T-I"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-K-I-N-Q-L-A-V-A-G-T-L-E-S-G-D-V-M-I-R-I-A-P-L-D-T-Q-D-I-D-L-Q-I-N-S-S-V-E-K-Q-F-G-E-A-I-R-A-T-I-L-E-V-L-S-R-Y-D-V-R-G-V-Q-L-N-V-D-D-K-G-A-L-D-C-I-L-R-A-R-L-E-T-L-L-A-R-A-S-G-I-A-A-L-P-W-E-D-R-Q"} +{"text": "### FUNCTION Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP ### SEQUENCE -M-N-F-L-A-H-L-H-L-A-H-L-A-D-S-S-L-S-G-N-L-L-A-D-F-V-R-G-N-P-A-T-H-Y-P-P-D-V-V-E-G-I-Y-M-H-R-R-I-D-V-M-T-D-N-L-P-E-V-R-E-A-R-E-W-F-R-H-E-T-R-R-V-A-P-I-T-L-D-V-M-W-D-H-F-L-S-R-H-W-T-Q-I-S-P-D-F-P-L-Q-A-F-V-G-Y-A-H-A-Q-V-A-T-I-L-P-D-S-P-P-R-F-V-N-L-N-D-Y-L-W-S-E-K-W-L-E-R-Y-R-D-M-D-F-I-Q-N-V-L-N-G-M-A-N-R-R-P-R-L-D-A-L-R-D-S-W-Y-D-L-D-A-H-Y-D-A-L-E-E-R-F-W-H-F-Y-P-R-M-M-A-Q-A-A-R-K-A-L"} +{"text": "### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate and magnesium starvation, but also in stationary phase and during nitrogen starvation Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway ### SEQUENCE -M-K-N-L-I-A-E-L-L-L-K-L-A-Q-K-E-E-E-S-K-E-L-V-A-Q-V-E-A-L-E-I-I-V-T-A-M-L-R-N-M-A-Q-N-E-Q-E-M-L-I-R-Q-V-E-G-A-L-E-G-V-K-P-D-A-S-V-P-D-H-D-T-E-L-L-R-Q-Y-V-K-K-L-L-R-H-P-R-H"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-D-D-V-A-L-P-L-Q-F-T-D-A-A-A-N-K-V-K-S-L-I-A-D-E-D-N-P-N-L-K-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-D-Q-V-N-E-G-D-M-T-I-E-K-Q-G-V-G-L-V-V-D-P-M-S-L-Q-Y-L-V-G-G-S-V-D-Y-T-E-G-L-E-G-S-R-F-I-V-T-N-P-N-A-K-S-T-C-G-C-G-S-S-F-S-I"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-I-S-R-V-T-E-A-L-S-K-V-K-G-S-I-G-S-N-E-R-H-A-L-P-G-V-I-G-D-D-L-L-R-F-G-K-L-P-L-C-L-F-I-C-I-I-L-T-A-V-T-V-V-T-T-A-H-H-T-R-L-L-T-A-Q-R-E-Q-L-V-L-E-R-D-A-L-D-I-E-W-R-N-L-I-L-E-E-N-A-L-G-D-H-S-R-V-E-R-I-A-T-E-K-L-Q-M-Q-H-V-D-P-S-Q-E-N-I-V-V-Q-K"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-K-I-I-K-D-A-L-A-G-T-L-E-S-S-D-V-M-I-R-I-G-P-S-S-E-P-G-I-R-L-E-L-E-S-L-V-K-Q-Q-F-G-A-A-I-E-Q-V-V-R-E-T-L-A-K-L-G-V-E-R-A-L-V-S-V-D-D-K-G-A-L-E-C-I-L-R-A-R-V-Q-A-A-A-L-R-A-A-E-Q-T-E-I-Q-W-S-A-L"} +{"text": "### FUNCTION This protein is involved in control of the biosynthesis of threonine ### SEQUENCE -M-N-R-I-S-T-T-T-I-T-T-I-T-I-T-T-G-N-G-A-G"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-P-V-A-E-T-S-Q-G-T-S-G-V-A-E-R-Y-A-S-S-L-F-E-L-A-L-E-A-G-T-V-E-A-V-Q-V-E-L-D-K-F-G-A-L-L-D-E-S-D-D-L-K-R-L-V-A-S-P-V-F-S-A-E-D-Q-F-K-A-I-S-A-I-C-E-K-A-G-I-A-G-L-A-V-N-F-L-K-V-V-A-N-N-R-R-L-F-A-V-P-G-M-I-R-A-Y-R-T-I-A-A-A-H-R-G-E-I-T-A-E-V-T-S-A-H-A-L-D-E-A-Q-E-T-E-L-K-A-A-L-K-S-V-T-G-K-D-V-A-I-S-V-T-V-D-P-S-I-L-G-G-L-I-V-K-V-G-S-R-Q-I-D-T-S-L-R-T-K-L-S-T-L-K-L-A-L-K-E-V-G"} +{"text": "### FUNCTION Involved in pyrimidine catabolism Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions ### SEQUENCE -M-P-K-K-I-I-V-P-V-G-T-S-K-P-I-A-P-F-S-P-G-T-L-A-D-G-V-V-Y-V-S-G-T-L-P-F-D-K-D-N-N-V-V-H-V-G-D-A-S-A-Q-T-R-H-V-L-E-T-I-K-S-V-I-E-T-A-G-G-T-M-E-D-V-T-M-N-H-I-F-I-T-D-W-A-N-Y-Q-A-V-N-T-V-Y-A-E-Y-F-P-G-D-K-P-A-R-Y-C-I-Q-C-G-L-V-K-P-D-A-L-V-E-I-A-T-V-A-H-I-G-K"} +{"text": "### FUNCTION Catalyzes the transfer of an acetyl group from acetyl coenzyme A -acetylspermidine, chloramphenicol, puromycin, polymyxin B, and 4-aminobutyrate ethyl ester ### SEQUENCE -M-N-F-V-L-S-D-V-A-D-A-E-A-E-K-A-I-R-D-P-L-V-A-Y-N-L-A-R-F-G-E-S-D-K-R-D-L-N-I-T-I-R-N-D-D-N-S-V-T-G-G-L-V-G-H-T-A-R-G-W-L-Y-V-Q-L-L-F-V-P-E-A-M-R-G-Q-G-I-A-P-K-L-L-A-M-A-E-E-E-A-R-K-R-G-C-M-G-A-Y-I-D-T-M-N-P-D-A-L-R-T-Y-E-R-Y-G-F-T-K-I-G-S-L-G-P-L-S-S-G-Q-S-I-T-W-L-E-K-R-F"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-M-E-A-A-A-K-R-V-H-I-I-Q-G-E-Y-K-V-V-S-D-P-D-V-V-M-T-T-I-L-G-S-C-V-A-A-C-L-R-D-P-V-A-G-L-G-G-M-N-H-F-L-L-P-G-T-G-N-V-T-G-G-D-A-T-R-Y-G-V-H-L-M-E-L-L-I-N-G-L-L-K-Q-G-A-R-R-D-R-L-E-A-K-V-F-G-G-A-K-T-I-A-S-F-S-N-V-G-E-Q-N-A-I-F-A-M-Q-F-L-K-D-E-G-I-P-V-I-S-S-S-T-G-G-D-H-G-R-K-I-E-F-W-P-V-S-G-R-A-R-Q-H-P-L-S-G-A-E-T-Q-K-T-V-A-M-E-T-R-P-V-P-A-P-K-P-V-A-N-D-I-E-F-F"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-S-A-K-P-H-E-V-K-R-E-W-F-V-I-D-A-Q-D-K-V-L-G-R-V-A-A-E-V-A-S-R-L-R-G-K-H-K-P-E-Y-T-P-H-V-D-T-G-D-Y-I-I-V-I-N-A-D-K-L-R-V-T-G-A-K-F-E-D-K-K-Y-F-R-H-S-G-F-P-G-G-I-Y-E-R-T-F-R-E-M-Q-E-Q-F-P-G-R-A-L-E-Q-A-V-K-G-M-L-P-K-G-P-L-G-Y-A-M-I-K-K-L-K-V-Y-A-G-A-E-H-A-H-A-A-Q-Q-P-K-V-L-E-L-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-I-N-A-T-L-F-A-Q-I-I-V-F-F-G-L-V-W-F-T-M-K-F-V-W-P-P-I-A-K-A-L-D-E-R-A-A-K-V-A-E-G-L-A-A-A-E-R-G-K-S-D-F-E-Q-A-E-K-K-V-A-E-L-L-A-E-G-R-N-Q-V-S-E-M-V-A-N-A-E-K-R-A-A-K-I-V-E-E-A-K-E-Q-A-S-S-E-A-A-R-I-A-A-Q-A-K-A-D-V-E-Q-E-L-F-R-A-R-E-S-L-R-E-Q-V-A-V-L-A-V-K-G-A-E-S-I-L-R-S-E-V-D-A-S-K-H-A-K-L-L-D-T-L-K-Q-E-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-V-E-Q-K-A-Q-I-V-K-D-F-Q-R-K-E-G-D-T-G-S-S-E-V-Q-V-A-L-L-T-F-R-I-N-D-L-T-P-H-F-K-A-N-P-K-D-H-H-S-R-R-G-L-L-K-M-V-S-Q-R-R-R-L-L-A-Y-L-R-R-T-Q-P-D-T-Y-R-A-L-I-T-R-L-G-L-R-K"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-E-Q-T-Q-Q-Q-N-S-E-E-A-V-E-N-V-E-A-V-E-T-V-E-T-V-G-N-A-D-G-V-Q-E-Q-A-A-A-E-P-A-Y-E-D-L-Q-A-R-I-A-E-L-E-A-Q-L-K-D-E-Q-L-R-A-L-A-N-E-Q-N-L-R-R-R-H-Q-Q-E-I-A-D-T-H-K-F-A-G-Q-K-F-A-V-E-M-L-P-V-K-D-Y-L-E-M-A-L-L-D-Q-S-G-N-F-D-A-L-K-M-G-V-Q-M-T-L-N-E-L-Q-K-A-F-D-A-T-Q-I-K-E-I-N-P-K-A-G-D-K-L-D-P-N-I-H-Q-A-M-Q-A-V-A-S-E-Q-E-P-N-T-V-V-G-V-M-K-K-G-Y-T-L-S-D-R-V-L-R-P-A-M-V-T-V-A-Q-K-E-A"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters ### SEQUENCE -M-S-D-E-S-P-I-I-F-T-D-S-C-C-A-K-V-A-D-L-I-A-E-E-N-N-P-D-L-K-L-R-V-F-V-N-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-I-K-N-D-D-D-F-E-I-E-K-N-G-L-V-F-L-V-D-P-M-S-Y-Q-Y-L-V-G-A-E-I-D-Y-T-E-S-L-Q-G-S-Q-F-V-I-R-N-P-N-A-E-T-T-C-G-C-G-S-S-F-S-V"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-A-M-N-K-L-N-F-L-L-L-L-A-V-C-V-S-A-F-S-V-V-M-Q-Q-N-Q-Y-R-L-N-F-T-A-L-D-K-A-K-K-Q-E-I-A-L-E-Q-D-Y-A-Q-M-R-L-Q-Q-A-R-L-A-N-H-E-A-I-R-A-A-A-E-K-Q-N-L-H-P-P-V-S-G-N-T-F-M-V-E-H-Q-R"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-V-K-T-G-G-K-Q-Y-K-V-S-V-G-E-K-L-K-V-E-Q-I-P-A-E-L-D-S-Q-I-E-L-T-E-V-L-M-I-A-D-G-E-S-V-K-V-G-A-P-F-I-E-G-A-K-V-T-A-K-V-V-A-H-G-R-G-E-K-V-R-I-F-K-M-R-R-R-K-H-Y-Q-K-R-Q-G-H-R-Q-N-F-T-Q-I-E-I-V-A-I-A"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-H-T-T-R-L-R-R-A-R-K-T-R-A-R-I-A-D-L-K-M-V-R-L-C-V-F-R-S-N-N-H-I-Y-A-Q-V-I-S-A-E-G-D-K-V-L-A-Q-A-S-T-L-E-A-E-V-R-G-S-L-K-S-G-S-N-V-E-A-A-A-I-V-G-K-R-I-A-E-K-A-K-A-A-G-V-E-K-V-A-F-D-R-S-G-F-Q-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-N-G-L-S-F"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-I-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-S-V-G-D-I-I-K-V-A-V-K-D-A-A-P-R-G-R-V-K-K-G-D-V-Y-N-A-V-V-V-R-T-A-K-G-V-R-R-P-D-G-A-L-I-K-F-D-N-N-A-A-V-L-L-N-N-K-L-E-P-L-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-R-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-T-K-N-V-R-T-L-Q-G-K-V-V-S-D-K-M-D-K-T-V-T-V-L-V-E-R-K-V-K-H-P-L-Y-G-K-I-I-R-L-S-T-K-I-H-A-H-D-E-N-N-Q-Y-G-I-G-D-V-V-V-I-S-E-S-R-P-L-S-K-T-K-S-W-V-V-S-E-L-V-E-K-A-R-S-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-T-R-L-K-Y-R-K-Q-Q-K-G-R-N-T-G-I-A-T-R-G-N-K-V-S-F-G-E-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-H-I-K-R-G-G-R-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-I-Q-V-R-M-G-G-G-K-G-N-V-E-Y-Y-I-A-E-I-K-P-G-K-V-L-Y-E-M-D-G-V-P-E-E-L-A-R-E-A-F-E-L-A-A-A-K-L-P-I-P-T-T-F-V-V-R-Q-V-G-Q"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-R-V-N-A-Q-H-K-N-A-R-I-S-A-Q-K-A-R-L-V-A-D-L-I-R-G-K-D-V-A-Q-A-L-N-I-L-A-F-S-P-K-K-G-A-E-L-I-K-K-V-L-E-S-A-I-A-N-A-E-H-N-N-G-A-D-I-D-E-L-K-V-V-T-I-F-V-D-K-G-P-S-L-K-R-F-Q-A-R-A-K-G-R-G-N-R-I-E-K-Q-T-C-H-I-N-V-T-V-G-N"} +{"text": "### FUNCTION Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage ### SEQUENCE -M-L-Q-S-I-P-A-L-P-V-G-D-I-K-K-S-I-G-F-Y-C-D-K-L-G-F-T-L-V-H-H-E-D-G-F-A-V-L-M-C-N-E-V-R-I-H-L-W-E-A-S-D-E-G-W-R-S-R-S-N-D-S-P-V-C-T-G-A-E-S-F-I-A-G-T-A-S-C-R-I-E-V-E-G-I-D-E-L-Y-Q-H-I-K-P-L-G-I-L-H-P-N-T-S-L-K-D-Q-W-W-D-E-R-D-F-A-V-I-D-P-D-N-N-L-I-S-F-F-Q-Q-I-K-S"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin that inhibits the endonuclease activity of cognate toxin LsoA but not that of non-cognate toxin RnlA ### SEQUENCE -M-K-K-D-K-K-Y-Q-I-E-A-I-K-N-K-D-K-T-L-F-I-V-Y-A-T-D-I-Y-S-P-S-E-F-F-S-K-I-E-S-D-L-K-K-K-K-S-K-G-D-V-F-F-D-L-I-I-P-N-G-G-K-K-D-R-Y-V-Y-T-S-F-N-G-E-K-F-S-S-Y-T-L-N-K-V-T-K-T-D-E-Y-N-D-L-S-E-L-S-A-S-F-F-K-K-N-F-D-K-I-N-V-N-L-L-S-K-A-T-S-F-A-L-K-K-G-I-P-I"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-S-T-V-K-G-Q-T-R-R-E-R-P-R-G-A-R-P-H-G-L-T-K-Q-K-R-Q-E-I-K-E-A-F-D-L-F-D-T-D-N-S-G-T-I-D-A-K-E-L-N-V-A-M-R-A-L-G-F-E-M-T-E-E-Q-I-N-Q-M-I-A-D-V-D-K-D-G-S-G-S-I-D-Y-E-E-F-E-H-M-M-T-A-K-I-G-E-R-D-S-K-E-E-L-T-K-A-F-S-I-I-D-Q-D-K-N-G-K-I-S-D-V-D-I-Q-R-I-A-K-E-L-G-E-N-F-T-Y-Q-E-I-Q-E-M-V-Q-E-A-D-R-N-G-D-G-E-I-D-F-D-E-F-I-R-M-M-R-R-T-G-Y-G-Y"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-D-G-I-K-Y-A-V-F-T-D-K-S-I-R-L-L-G-K-N-Q-Y-T-S-N-V-E-S-G-S-T-R-T-E-I-K-H-W-V-E-L-F-F-G-V-K-V-I-A-M-N-S-H-R-L-P-G-K-S-R-R-M-G-P-I-M-G-H-T-M-H-Y-R-R-M-I-I-T-L-Q-P-G-Y-S-I-P-P-L-R-K-K-R-T"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-L-K-K-N-P-F-V-A-N-H-L-L-K-K-I-D-K-L-N-T-K-A-E-K-E-I-I-V-T-W-S-R-A-S-T-I-I-P-T-M-I-G-H-T-I-A-I-H-N-G-K-E-H-L-P-I-Y-I-T-D-S-M-V-G-H-K-L-G-E-F-A-P-T-L-N-F-R-G-H-A-K-S-D-N-R-S-R-R"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-G-V-T-K-K-P-D-L-N-D-P-V-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-V-V-I-L-G-T-I-A-C-N-V-G-L-A-V-L-E-P-S-M-I-G-E-P-A-D-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-F-P-V-F-Q-I-L-R-T-V-P-N-K-L-L-G-V-L-L-M-V-S-V-P-A-G-L-L-T-V-P-F-L-E-N-V-N-K-F-Q-N-P-F-R-R-P-V-A-T-T-V-F-L-I-G-T-A-V-A-L-W-L-G-I-G-A-T-L-P-I-D-K-S-L-T-L-G-L-F"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-I-K-R-G-Y-I-A-R-R-R-R-T-K-I-R-L-F-A-S-S-F-R-G-A-H-S-R-L-T-R-T-I-T-Q-Q-K-I-R-A-L-V-S-A-H-R-D-R-D-R-K-K-R-D-F-R-R-L-W-I-T-R-I-N-A-V-I-R-E-R-G-V-S-Y-S-Y-S-R-L-I-H-D-L-Y-K-R-Q-L-L-L-N-R-K-I-L-A-Q-I-A-I-S-N-R-N-C-L-Y-M-I-S-N-E-I-I-K-E-V-D-W-K-E-S-T-R-I-I"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-I-E-V-F-L-F-G-I-V-L-G-L-I-P-I-T-L-A-G-L-F-V-T-A-Y-L-Q-Y-R-R-G-D-Q-L-D-L"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-T-N-L-N-L-P-S-I-F-V-P-L-V-G-L-V-F-P-A-I-A-M-A-S-L-F-L-H-V-Q-K-N-K-I-V"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-V-P-T-A-F-L-L-I-I-Y-V-K-T-V-S-Q-N-D"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-I-V-S-L-A-W-A-A-L-M-V-V-F-T-F-S-L-S-L-V-V-W-G-R-S-G-L"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-D-R-V-N-R-L-A-A-Q-R-A-V-V-I-F-S-M-S-S-C-C-M-C-H-T-V-T-R-L-F-C-E-L-G-V-N-P-T-V-V-E-L-D-E-D-P-R-G-K-E-M-E-K-A-L-A-R-L-L-G-R-S-P-A-V-P-A-V-F-I-G-G-R-L-V-G-S-T-D-K-V-M-S-L-H-L-S-G-N-L-V-P-L-L-R-N-A-G-A-L-W-V"} +{"text": "### FUNCTION Acts as a sulfur carrier required for 2-thiolation of mcm that is covalently conjugated via an isopeptide bond to lysine residues of target proteins The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates ### SEQUENCE -M-H-L-T-L-E-F-G-G-G-L-E-L-L-L-E-K-S-T-K-V-H-K-V-D-L-Q-P-N-D-G-D-G-K-V-V-M-K-G-L-L-A-W-V-K-S-N-L-I-K-E-R-P-E-M-F-L-K-G-D-S-V-R-P-G-V-L-V-L-I-N-D-C-D-W-E-L-C-G-G-L-D-A-E-L-E-E-K-D-V-V-V-F-I-S-T-L-H-G-G"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-I-V-S-L-A-W-A-A-L-M-V-V-F-T-F-S-L-S-L-V-V-W-G-R-S-G-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-I-V-S-L-A-W-A-A-L-M-V-V-F-T-F-S-L-S-L-V-V-W-G-R-S-G-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-I-V-S-L-A-W-A-A-L-M-V-V-F-T-F-S-L-S-L-V-V-W-G-R-S-G-L"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-S-Q-T-Y-L-N-I-A-D-N-S-G-A-R-K-I-M-C-I-R-V-L-G-A-S-N-R-K-C-A-H-I-G-D-V-I-I-A-I-I-K-E-A-V-P-N-M-P-L-E-K-S-E-V-V-R-A-V-V-I-R-T-C-K-E-F-E-R-D-N-G-M-M-I-R-S-D-D-N-A-A-V-V-I-D-Q-E-G-N-P-K-G-T-R-V-F-G-P-V-A-Q-E-L-R-Q-L-N-F-T-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-T-I-S-I-S-C-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-K-Q-L-R-D-P-F-E-D-H-E-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-I-Q-T-K-K-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-Q-S-N-P-N-E-Q-T-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-V-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-I-E-V-F-L-F-G-I-V-L-G-L-I-P-I-T-L-A-G-L-F-V-T-A-Y-L-Q-Y-R-R-G-D-Q-L-D-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-S-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-V-P-T-A-F-L-L-I-I-Y-V-K-T-V-S-Q-S-D"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-I-V-S-L-A-W-A-A-L-M-V-V-F-T-F-S-L-S-L-V-V-W-G-R-S-G-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-L-F-V-Y-T-V-V-I-F-F-V-S-L-F-I-F-G-F-L-S-N-D-P-G-R-N-P-G-R-E-E"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-W-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-L-I-L-G-Y-V-S-G-K-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-K-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-S-F-N"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-M-K"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-R-I-S-T-K-K-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-N-K-K-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-M-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5 This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells ### SEQUENCE -M-Y-R-M-Q-L-L-S-C-I-A-L-S-L-A-L-I-T-N-S-A-P-T-S-S-S-T-K-K-T-Q-L-Q-L-E-H-L-L-L-D-L-Q-M-L-L-N-G-I-N-N-Y-K-N-P-K-L-T-R-M-L-T-F-K-F-Y-M-P-K-K-A-T-E-L-K-H-L-Q-C-L-E-E-E-L-K-P-L-E-E-V-L-N-L-A-Q-S-K-N-F-H-L-R-D-T-R-D-I-I-S-N-I-N-V-L-V-L-E-L-K-G-S-E-T-T-F-T-C-E-Y-D-D-D-T-A-T-I-I-E-F-L-N-G-W-I-T-F-C-Q-S-I-I-S-T-L-T"} +{"text": "### FUNCTION Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5 This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells ### SEQUENCE -M-Y-R-M-Q-L-L-S-C-I-A-L-S-L-A-L-I-T-N-S-A-P-T-S-S-S-T-K-K-T-Q-L-Q-L-E-H-L-L-L-D-L-Q-M-L-L-N-G-I-N-N-Y-K-N-P-K-L-T-R-M-L-T-F-K-F-Y-M-P-K-K-A-T-E-L-K-H-L-Q-C-L-E-E-E-L-K-P-L-E-E-V-L-N-L-A-Q-S-K-N-F-H-L-R-D-T-R-D-I-I-S-N-I-N-V-L-V-L-E-L-K-G-S-E-T-T-F-T-C-E-Y-D-D-D-T-A-T-I-I-E-F-L-N-G-W-I-T-F-C-Q-S-I-I-S-T-L-T"} +{"text": "### FUNCTION Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5 This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells ### SEQUENCE -M-Y-R-M-Q-L-L-S-C-I-A-L-S-L-A-L-I-T-N-S-A-P-T-S-S-S-T-K-K-T-Q-L-Q-L-E-H-L-L-L-D-L-Q-M-L-L-N-G-I-N-N-Y-K-N-P-K-L-T-R-M-L-T-F-K-F-Y-M-P-K-K-A-T-E-L-K-H-L-Q-C-L-E-E-E-L-K-P-L-E-E-V-L-N-L-A-Q-S-K-N-F-H-L-R-D-T-R-D-I-I-S-N-I-N-V-L-V-L-E-L-K-G-S-E-T-T-F-T-C-E-Y-D-D-D-T-A-T-I-I-E-F-L-N-G-W-I-T-F-C-Q-S-I-I-S-T-L-T"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase , that is believed not to be involved in catalysis Complex I functions in the transfer of electrons from NADH to the respiratory chain The immediate electron acceptor for the enzyme is believed to be ubiquinone ### SEQUENCE -M-W-F-E-I-L-P-G-L-S-V-M-G-V-C-L-L-I-P-G-L-A-T-A-Y-I-H-R-F-T-N-G-G-K-E-K-R-V-A-H-F-G-Y-H-W-N-L-M-E-R-D-R-R-I-S-G-V-D-R-Y-Y-V-S-K-G-L-E-N-I-D"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-R-C-R-S-R-S-R-C-R-R-R-R-R-R-C-H-R-R-R-R-R-C-C-R-R-R-R-R-R-R-A-C-C-R-R-Y-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-R-S-R-C-R-R-R-R-R-R-C-Y-R-R-R-R-R-C-C-R-R-R-R-R-R-V-C-C-R-R-Y-T-V-I-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-P-S-R-S-R-C-R-R-R-R-R-R-C-R-R-R-R-R-R-C-C-R-R-R-R-R-V-C-C-R-R-Y-T-V-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-P-S-R-S-R-C-R-R-R-R-R-R-C-R-R-R-R-R-R-C-C-R-R-R-R-R-V-C-C-R-R-Y-T-V-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-C-R-P-R-R-R-C-R-R-R-R-R-R-S-C-R-A-R-R-R-A-T-R-C-C-R-R-R-Y-R-L-R-C-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-C-R-P-R-R-R-C-R-R-R-R-R-R-S-C-R-A-R-R-R-A-T-R-C-C-R-R-R-Y-R-L-R-C-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-C-R-R-R-R-R-C-R-R-R-R-R-R-R-C-R-A-R-R-R-A-M-R-C-C-R-R-R-Y-R-L-R-C-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-C-R-P-R-R-R-C-R-R-R-R-R-R-S-C-R-A-R-R-R-A-T-R-C-C-R-R-R-Y-R-L-R-S-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-R-C-R-S-Q-S-R-S-R-C-C-R-P-R-R-R-C-R-R-R-R-R-S-C-R-A-R-R-R-A-T-R-C-C-R-R-R-Y-R-L-R-C-R-R-Y"} +{"text": "### FUNCTION May be involved in transcriptional regulation ### SEQUENCE -M-E-T-A-L-A-E-V-Q-L-S-C-L-L-C-E-Q-T-F-D-A-T-E-K-L-D-E-H-L-P-T-H-F-P-Q-P-V-S-T-G-Q-T-C-D-I-C-G-R-T-M-R-S-S-L-E-L-H-Q-H-Y-K-R-Y-H-E-A-H-V-P-N-T-E-G-H-F-Q-C-Q-L-C-D-K-V-F-L-L-Q-D-H-L-K-V-H-V-K-I-E-H-A-T-D-G-Y-Q-P-D-E-K-S-L-D-W-Q-H-Y-S-P-R-S-L-D-T-T-N-D-Y-K-L-D-P-I-L-C-P-P-P-K-R-K-Y-P-P-R-S-P-F-F-N-P-N-L-W-L-G-A-D-N-C-F-M"} +{"text": "### FUNCTION Component of the COP9 signalosome complex conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity ### SEQUENCE -M-K-P-S-L-A-A-D-E-M-F-S-E-G-P-G-Y-M-E-M-D-E-S-G-G-A-T-G-M-M-M-D-H-L-P-S-N-D-K-H-V-H-A-D-F-Y-N-D-F-D-D-L-F-D-E-D-N-W-A-K-M-K-T-D-G-K-Q"} +{"text": "### FUNCTION Colony queen number, a major feature of social organization, is associated with worker genotype for Gp-9 Colonies are headed by either a single reproductive queen ### SEQUENCE -M-K-T-F-V-L-H-I-F-I-F-A-F-V-A-F-A-S-A-S-R-D-S-A-K-K-I-G-S-Q-Y-D-N-Y-E-T-C-L-T-E-H-G-L-T-D-D-D-I-F-S-I-G-E-V-S-S-G-Q-H-K-T-N-H-E-D-T-E-L-H-K-N-G-C-V-M-Q-C-M-L-E-K-D-G-L-M-S-G-A-D-Y-D-E-E-K-M-R-E-D-Y-I-K-E-T-G-A-Q-P-G-D-Q-R-I-E-A-L-N-T-C-M-Q-E-T-K-D-M-E-D-K-C-D-K-S-L-I-L-V-A-C-V-L-A-A-E-A-V-L-A-D-S-S-E-G-A"} +{"text": "### FUNCTION Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body ### SEQUENCE -M-Q-H-N-T-F-L-P-N-D-A-V-E-E-Q-K-Q-N-P-Y-Y-G-I-L-R-A-V-E-T-D-L-R-L-G-Q-R-W-C-E-L-K-V-H-V-L-D-I-D-L-K-T-K-R-P-L-L-S-G-I-P-V-N-G-Q-L-K-D-K-L-Q-Y-V-L-P-L-Y-L-Q-E-T-I-S-I-E-F-L-S-S-V-F-D-S-M-K-K-L-S-L-P-L-V-K-D-A-R-G-L-S-G-D-E-F-F-L-Y-L-G-I-M-C-S-D-S-T-I-V-Y-Y-K-I-T-D-G-L-I-K-P-R-Q-N-D-E-E"} +{"text": "### FUNCTION Anticoagulant protein May prevent the complex of factors Xa as well ### SEQUENCE -A-T-P-F-G-G-S-S-Y-E-G-H"} +{"text": "### FUNCTION Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract many smooth muscles ### SEQUENCE -S-N-S-K-C-P-D-G-P-D-C-F-V-G-L-M"} +{"text": "### FUNCTION Induces relaxation of arterial smooth muscle, by targeting bradykinin receptors ### SEQUENCE -R-P-P-G-F-S-P-F-R-I-Y"} +{"text": "### FUNCTION Induces smooth muscle contraction May target bradykinin receptors ### SEQUENCE -R-P-P-G-F-S-P-F-R-V-A-P-A-S"} +{"text": "### FUNCTION Induces smooth muscle contraction May target bradykinin receptors ### SEQUENCE -V-P-P-G-F-T-P-F-R"} +{"text": "### FUNCTION Hypotensive neuropeptide ### SEQUENCE -Q-E-Y-T-G-W-M-D-F"} +{"text": "### FUNCTION Has antiplatelet activities on guinea pig, followed by human, rabbit and rat platelet-rich plasma ### SEQUENCE -D-C-A-S-G-P-C-C-R-D-C-K-F-L-E-E-G-T-I-C-N-M-A-R-G-D-D-M-D-D-Y-C-N-G-K-T-C-D-C-P-R-N-P-H-K-W-P-A-P"} +{"text": "### FUNCTION Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta , polymerize to form an insoluble fibrin matrix Fibrin has a major function in hemostasis as one of the primary components of blood clots ### SEQUENCE -E-D-T-G-T-F-E-E-G-H-G-G-V-R"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-K-N-T-N-P-N-S-Q-P-V-E-L-N-R-T-S-L-F-L-G-R-L-L-I-F-V-L-G-I-L-F-S-S-Y-I-F-N"} +{"text": "### FUNCTION Involved in UV protection and mutation ### SEQUENCE -M-S-T-V-Y-H-R-P-A-D-P-S-G-D-D-S-Y-V-R-P-L-F-A-D-R-C-Q-A-G-F-P-S-P-A-T-D-Y-A-E-Q-E-L-D-L-N-S-Y-C-I-S-R-P-A-A-T-F-F-L-R-A-S-G-E-S-M-N-Q-A-G-V-Q-N-G-D-L-L-V-V-D-R-A-E-K-P-Q-H-G-D-I-V-I-A-E-I-D-G-E-F-T-V-K-R-L-L-L-R-P-R-P-A-L-E-P-V-S-D-S-P-E-F-R-T-L-Y-P-E-N-I-C-I-F-G-V-V-T-H-V-I-H-R-T-R-E-L-R"} +{"text": "### FUNCTION Possesses antimicrobial activity sensitive to inorganic cations Binds specifically to the fungal plasma membrane Has no inhibitory effect on insect gut alpha-amylase ### SEQUENCE -N-L-C-E-R-A-S-L-T-W-T-G-N-C-G-N-T-G-H-C-D-T-Q-C-R-N-W-E-S-A-K-H-G-A-C-H-K-R-G-N-W-K-C-F-C-Y-F-N-C"} +{"text": "### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -A-T-Y-N-I-K-L-I-T-P-E-G-T-K-E-I-T-C-S-D-S-E-Y-I-L-D-A-A-E-E-K-G-L-D-L-P-Y-S-C-R"} +{"text": "### FUNCTION Involved in nuclear basic protein transition histones are replaced by spermatid specific proteins which are themselves replaced by protamines in late spermatids ### SEQUENCE -A-K-V-T-E-K-S-W-Q-P-Q-T-T-S-T-K-R-W-K-K-R-K-T-P-S-Q-P-R-S-R-G-K-V-R-K-I-Y-K-K-V-K-R-P-L-H-V-C-S-R-K-K-Y-S-P-K-V-I-T-T-S-R-R-Q-K-R-A-R-R-A-N-K-F-E-T-I-P"} +{"text": "### FUNCTION Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles ### SEQUENCE -G-L-S-D-G-E-W-Q-L-V-L-N-V-W-G-K-V-E-A-D-L-A-G-H-G-Q-E-V-L-I-R-L-F-K-G-H-P-E-T-L-E-K-F-D-K-F-K-H-L-K-S-E-K-G-S-E-D-L-K-K-H-G-N-T-V-E-T-A-L-E-G-I-L-K-K-K-A-L-E-L-F-K-N-D-I-A-A-K-T-K-E-L-G-F-L-G"} +{"text": "### FUNCTION Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals ### SEQUENCE -Q-R-T-N-D-F-I-K-A-C-G-R-E-L-V-R-V-W-V-E-I-C-G-S-V-S-W-G-R-T-A"} +{"text": "### FUNCTION Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta , polymerize to form an insoluble fibrin matrix Fibrin has a major function in hemostasis as one of the primary components of blood clots In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway Maternal fibrinogen is essential for successful pregnancy Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage May also facilitate the immune response via both innate and T-cell mediated pathways ### SEQUENCE -A-D-G-S-D-P-A-G-G-E-F-L-A-E-G-G-G-V-R"} +{"text": "### FUNCTION Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta , polymerize to form an insoluble fibrin matrix Fibrin has a major function in hemostasis as one of the primary components of blood clots In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway Maternal fibrinogen is essential for successful pregnancy Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage May also facilitate the immune response via both innate and T-cell mediated pathways ### SEQUENCE -T-D-T-K-E-S-D-F-L-A-E-G-G-G-V-R"} +{"text": "### FUNCTION Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta , polymerize to form an insoluble fibrin matrix Fibrin has a major function in hemostasis as one of the primary components of blood clots In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway Maternal fibrinogen is essential for successful pregnancy Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage May also facilitate the immune response via both innate and T-cell mediated pathways ### SEQUENCE -T-D-G-K-E-G-E-F-I-A-E-G-G-G-V-R"} +{"text": "### FUNCTION Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta , polymerize to form an insoluble fibrin matrix Fibrin has a major function in hemostasis as one of the primary components of blood clots In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway Maternal fibrinogen is essential for successful pregnancy Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage May also facilitate the immune response via both innate and T-cell mediated pathways ### SEQUENCE -T-K-T-E-G-S-F-L-A-E-G-G-G-V-R"} +{"text": "### FUNCTION Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta , polymerize to form an insoluble fibrin matrix Fibrin has a major function in hemostasis as one of the primary components of blood clots In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway Maternal fibrinogen is essential for successful pregnancy Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage May also facilitate the immune response via both innate and T-cell mediated pathways ### SEQUENCE -T-K-D-E-G-T-F-I-A-E-G-G-G-V-R"} +{"text": "### FUNCTION Has a vascular smooth muscle spasmogenic activity ### SEQUENCE -E-A-F-P-G-Q-S-T"} +{"text": "### FUNCTION Bradykinins are a potent but short-lived agent of arteriolar dilation and increased capillary permeability May cause hypotension ### SEQUENCE -A-R-P-P-G-F-S-P-F-R-I-V"} +{"text": "### FUNCTION May be calcium-dependent and galactose-specific ### SEQUENCE -C-S-C-Y-P-D-W-M-A-I-P-G-S-G-C-Y-K-Y-V-D-T-P-K-T-F-E-E-A-E-S-T-C-R-H-F-S-P-G-P-Y-G-F-G-H-L-A-S-V-H-S-T-E-E-Y-E-A-L-A-S-M-V-P-G-A-T-D-S-W-N-P-Q-V-F-I-G-L-R-L-I-D-G-V-S-P-A-W-T-D-G-S-Y-Y-D-Y-Q-N-W-C-G-N-D-P-N-A-H-P-D-G-Y-G-A-F-S-G-G-S-Y-C-N-G-Q-W-V-D-V-H-T-F-T-N-D-Q-F-P-F-K-C-K-L-P-C-I-E"} +{"text": "### FUNCTION Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction ### SEQUENCE -A-A-N-L-E-N-D-F-D-N-V-N-E-Q-L-Q-D-A-L-S-K-I-T-L-L-E-E-D-L-E-R-N-E-E-R-L-Q-T-A-T-E-R-L-E-E-A-S-K-Y-I-A-E-D-A-E-R-K-L-A-I-T-E-V-D-L-E-R-A-E-A-R-L-E-A-A-E-A-K-S-L-E-I-S-E-Q-E-A-S-Q-R-E-D-S-Y-E-E-T-I-R-D-L-T-Q-R-L-K-T-V-S-K-L-Q-K-E-V-D-R-L-E-D-E-L-L-A-E-K-E-K-Y-K-A-I-S-D-E-L-D-Q-T-F-A-E-L-A-G-Y"} +{"text": "### FUNCTION ELH acts as a neurotransmitter locally, upon neurons of the abdominal ganglion and as a hormone by diffusing into the circulating hemolymph and modulating the activity of other organs It specifically causes contraction of smooth muscle in the ovotestis and expulsion of the egg string ### SEQUENCE -I-S-I-N-Q-D-L-K-A-I-T-D-M-L-L-T-E-Q-I-R-E-R-Q-R-Y-L-A-D-L-R-Q-R-L-L-E-K"} +{"text": "### FUNCTION Vasotocin is an antidiuretic hormone ### SEQUENCE -M-S-A-M-G-W-T-L-L-A-A-A-L-L-A-I-S-A-Q-S-N-G-C-Y-I-Q-N-C-P-R-G-G-K-R-A-V-E-T-E-L-H-S-C-A-A-C-G-L-G-G-Q-C-V-G-P-S-I-C-C-G-G-L-L-G-G-G-R-G-G-G-C-I-V-G-G-P-L-S-A-P-C-K-R-E-N-L-H-P-E-P-C-R-P-G-G-G-S-S-C-G-L-E-G-I-C-A-A-P-G-I-C-C-T-D-V-T-C-S-I-D-A-T-C-D-D-V-T-E-K-A-G-V-T-F-S-G-A-T-G-G-L-A-N-P-T-G-D-L-L-R-K-V-L-L-L-A-N-A-D-L-E"} +{"text": "### FUNCTION Water-borne pheromone that attract the marine mollusk Aplysia into breeding aggregations and coordinate male and female reproductive behavior within the aggregation ### SEQUENCE -D-Q-N-C-D-I-G-N-I-T-S-Q-C-E-M-Q-H-Q-N-C-D-D-A-N-G-C-N-T-I-I-E-E-C-K-T-S-M-V-E-R-C-Q-N-Q-E-F-E-S-A-S-G-S-T-T-L-G-P-Q"} +{"text": "### FUNCTION Water-borne pheromone that attract the marine mollusk Aplysia into breeding aggregations and coordinate male and female reproductive behavior within the aggregation ### SEQUENCE -N-N-K-C-D-L-E-F-A-S-S-E-C-Q-M-R-Y-Q-D-C-G-E-A-S-N-C-T-A-L-I-E-E-C-K-T-S-L-Q-E-E-C-D-Q-A-S-S-E-S-S-S-T-T-I-R-P-E"} +{"text": "### FUNCTION Water-borne pheromone that attract the marine mollusk Aplysia into breeding aggregations and coordinate male and female reproductive behavior within the aggregation ### SEQUENCE -N-N-K-C-D-I-E-F-A-T-S-E-C-E-M-R-Y-Q-D-C-G-E-A-S-S-C-T-A-L-I-E-E-C-K-T-S-L-Q-E-E-C-N-Q-A-S-S-D-E-S-S-T-T-V-R-P-E"} +{"text": "### FUNCTION Mast cell degranulating peptide ### SEQUENCE -A-S-V-H-E-F-L-V-K"} +{"text": "### FUNCTION Component of the abdominal endocuticle ### SEQUENCE -Q-K-P-G-E-A-V-I-L-E-Q-S-I-D-N-D-G-L-G-Q-Y-T-F-G-F-K-T-S-D-G-L-I-R-Q-E-Q-G-V-V-K-N-Q-G-T-E-N-E-A-L-E-V-R-G-T-I-T-W-L-G-A-D-G-K-D-Y-S-I-N-F-V-A-D-E-N-G-F-Q-P-Q-Y-T-Q"} +{"text": "### FUNCTION Component of the abdominal endocuticle ### SEQUENCE -Q-V-P-F-A-P-R-P-V-I-P-G-A-F-V-P-I-V-S-Q-N-F-D-L-N-G-V-D-G-S-Y-T-F-S-Y-E-S-A-D-G-S-A-R-Q-E-S-G-V-V-N-A-P-G-T-P-L-E-A-Q-A-V-Q-G-S-Y-T-Y-V-G-T-D-G-V-P-V-Q-V-N-Y-V-A-D-E-N-G-F-Q-P-V-G-N-V-V-A-P-A-I-S-R-A-V-A-A-Q-V-A-Q-A-R-A-E-G-P-I-L-P-G-V-P-T-P-I-P-F-R-G-R-P-F"} +{"text": "### FUNCTION Component of the abdominal endocuticle ### SEQUENCE -Q-A-P-P-D-K-V-I-P-I-I-S-Q-N-E-V-R-N-P-D-G-S-Y-Q-W-N-Y-E-T-G-N-G-I-K-A-D-E-T-G-T-L-K-K-G-S-K-P-D-E-G-D-F-I-V-A-Q-G-S-F-S-Y-T-G-P-D-G-T-A-Y-S-V-Q-Y-Q-A-D-D-E-N-G-F-V-P-Q-G-A-H-F-P-T-P-P-P-I-P-P-A-I-Q-R-A-L-D-Y-L-A-T-L-P-S-T-P-E-P-R-P"} +{"text": "### FUNCTION Component of the abdominal endocuticle ### SEQUENCE -Q-F-G-N-Y-Y-Q-P-Q-P-T-Y-S-P-P-A-R-Q-Q-V-P-I-L-Q-Y-S-N-E-V-N-P-D-G-S-Y-A-Y-S-Y-Q-T-G-N-G-I-A-A-Q-E-Q-G-Y-L-K-N-P-G-Q-R-D-L-E-A-E-N-V-Q-G-T-F-S-Y-T-A-P-D-G-T-P-I-S-L-R-Y-V-A-D-E-N-G-F-R-A-E-G-A-H-L-P-T-P-P-P-I-P-E-A-I-A-R-S-L-E-V-I-A-R-T-P-Q-Q-P-F-Q-P-Q-P-Q-Y-N-P-F-R-R-F"} +{"text": "### FUNCTION Specifically inhibits an intracellular serine proteinase ### SEQUENCE -S-A-G-K-F-I-V-I-F-K-N-G-V-S-D-D-K-I-R-E-T-K-D-E-V-I-A-E-G-G-T-I-T-N-E-Y-N-M-P-G-M-K-G-F-A-G-E-L-T-P-Q-S-L-T-K-F-Q-G-L-Q-G-D-L-I-D-S-I-E-E-D-G-I-V-T-T-Q"} +{"text": "### FUNCTION Specifically inhibits an endogenous intracellular serine proteinase ### SEQUENCE -S-A-G-K-F-I-V-I-F-K-N-D-V-S-E-D-K-I-R-E-T-K-D-E-V-I-A-E-G-G-T-I-T-N-E-Y-N-M-P-G-M-K-G-F-A-G-E-L-T-P-Q-S-L-T-K-F-Q-G-L-Q-G-D-L-I-D-S-I-E-E-D-G-I-V-T-T-Q"} +{"text": "### FUNCTION Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly ### SEQUENCE -M-S-N-T-A-P-G-P-T-V-A-N-K-R-D-E-K-H-R-H-V-V-N-V-V-L-E-L-P-T-E-I-S-E-A-T-H-P-V-L-A-T-M-L-S-K-Y-T-R-M-S-S-L-F-N-D-K-C-A-F-K-L-D-L-L-R-M-V-A-V-S-R-T-R-R"} +{"text": "### FUNCTION Required for efficient viral DNA synthesis and the late accumulation of viral IE transcripts ### SEQUENCE -M-G-G-S-P-V-P-Q-L-T-T-V-T-Q-G-L-M-P-S-V-R-M-D-F-R-A-R-R-P-L-R-R-L-A-F-Y-A-P-R-A-R-R-R-L-F-Q-N-H-I-H-P-E-Q-R-R-V-L-V-G-E-G-D-E-E-M-L-P-D-L-P-M-E-I-D-I-V-I-D-R-P-P-Q-Q-P-L-P-N-P-L-V-L-L-L-D-D-V-P-P-H-V-P-G-F-A-P-Y-R-V-P-R-P-H-P-M-I-P-E-E-H-W-D-Q-F"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-V-K-L-A-F-P-R-E-L-R-L-L-T-P-K-H-F-T-Y-V-F-Q-Q-P-Q-R-A-S-S-P-E-I-T-I-L-G-R-P-N-E-L-G-H-P-R-I-G-L-T-I-A-K-K-N-V-K-R-A-H-E-R-N-R-I-K-R-L-A-R-E-S-F-R-L-N-Q-H-E-L-P-P-M-D-F-V-V-L-V-R-K-G-V-A-E-L-D-N-R-A-L-T-E-A-L-G-K-L-W-R-R-H-C-R-L-A-R-A-S"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-N-D-K-L-I-V-E-R-Q-E-V-E-N-K-S-E-G-G-I-V-L-T-S-Q-S-V-K-K-S-N-R-G-K-V-I-A-A-G-L-G-K-R-L-E-N-G-E-R-A-S-M-E-V-K-V-G-D-V-V-I-F-N-D-G-Y-G-V-K-T-E-K-M-D-G-K-E-Y-L-I-L-S-E-S-D-V-L-A-I-V-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-E-R-Q-E-V-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-E-K-S-T-R-G-V-V-L-A-V-G-K-G-R-I-L-E-N-G-T-V-Q-P-L-D-V-K-V-G-D-T-V-I-F-A-E-S-Y-G-T-K-T-E-K-I-D-G-K-E-V-L-I-M-S-E-N-D-I-M-A-I-V-D"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-L-P-I-I-T-Y-P-H-P-L-L-K-K-R-S-E-P-V-T-L-F-D-E-E-L-R-Q-F-L-D-E-M-Y-I-T-M-L-A-K-N-G-V-G-L-A-A-V-Q-V-G-N-P-I-R-A-L-I-V-N-I-P-D-E-E-G-N-Q-E-R-E-N-L-L-E-I-I-N-P-E-F-L-S-K-E-G-E-I-Q-F-N-E-G-C-L-S-V-P-E-F-Y-E-D-V-T-R-F-D-R-V-R-L-T-Y-Q-D-R-Y-G-E-R-H-E-I-E-A-E-G-Y-L-A-V-A-L-Q-H-E-I-D-H-L-N-G-I-L-F-I-D-K-L-S-L-I-K-R-K-K-F-E-K-E-L-K-K-R-Q-R-A-S-L"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-Y-I-P-Y-V-I-E-K-T-G-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-S-G-E-I-N-D-G-V-A-S-S-I-V-S-Q-M-L-F-L-E-A-E-D-P-E-K-D-I-Y-L-Y-I-N-S-P-G-G-V-I-T-S-G-M-S-I-Y-D-T-M-N-Y-V-K-P-D-I-C-T-I-C-I-G-Q-A-A-S-M-G-A-F-L-L-S-C-G-T-K-G-K-R-F-S-L-P-N-S-R-I-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-T-D-I-E-I-Q-A-K-E-I-L-R-L-K-S-I-L-N-G-I-L-A-S-N-T-G-Q-P-L-E-K-I-A-K-D-T-D-R-D-F-F-M-S-A-Q-E-S-K-E-Y-G-L-I-D-N-V-L-E-K-S-F-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-N-M-T-K-M-A-K-A-N-E-I-K-R-E-W-V-V-L-D-A-E-G-K-T-F-G-R-L-M-T-Q-V-A-T-L-L-R-G-K-H-R-P-D-Y-T-P-H-V-D-C-G-D-F-V-V-I-V-N-A-S-K-V-V-F-S-G-L-K-L-E-A-K-E-Y-F-T-H-S-G-Y-F-G-S-T-K-S-Q-T-L-Q-E-L-L-E-K-N-P-E-K-L-F-R-L-A-A-R-G-M-L-P-K-T-K-L-G-R-A-M-L-K-K-L-K-V-Y-A-G-A-E-H-P-H-T-A-Q-V-T-K"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-L-E-G-I-I-R-E-S-I-S-K-S-A-V-K-A-L-R-N-D-G-Y-L-I-A-N-I-Y-G-K-G-Q-E-N-T-H-C-A-F-K-K-N-D-F-I-R-A-V-K-S-K-T-N-I-I-F-P-V-K-V-G-G-K-E-I-N-V-V-V-Q-E-Y-Q-K-D-P-I-T-S-D-L-L-H-V-D-L-M-L-V-Q-P-G-V-E-T-K-F-L-V-P-V-K-T-A-G-S-A-K-G-L-K-N-K-G-V-L-I-L-S-K-K-R-V-K-V-K-C-S-P-E-N-L-P-A-S-Y-E-L-D-V-S-D-L-D-V-G-D-A-I-L-V-R-D-L-P-E-L-P-N-V-K-V-I-E-K-E-S-V-A-I-V-G-V-I-K-A-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-L-V-V-G-L-G-N-P-G-K-T-Y-E-S-T-R-H-N-I-G-F-R-V-I-D-A-L-L-E-R-R-S-A-L-N-A-T-K-S-T-F-K-G-E-L-H-K-E-G-E-N-L-F-L-K-P-T-T-Y-M-N-L-S-G-E-S-A-L-P-V-S-T-F-Y-K-P-E-K-I-L-V-I-H-D-D-L-D-L-P-F-G-A-I-R-L-K-R-G-G-G-N-G-G-H-N-G-L-K-S-L-D-K-L-L-G-N-D-Y-Y-R-L-R-I-G-I-G-K-P-P-L-G-W-E-V-A-D-Y-V-L-A-R-F-S-Q-E-E-E-Q-E-L-E-E-R-L-F-P-H-A-K-E-A-I-E-S-F-L-E-G-K-M-E-W-D-R-L-V-S-R-Y-S-L-K-P-S-T-P-K-E-K-V"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-I-T-V-V-E-S-S-F-L-T-S-A-S-A-L-S-Q-T-P-P-P-K-N-S-E-V-V-F-I-G-R-S-N-V-G-K-S-T-L-I-N-L-I-V-D-S-K-G-L-A-K-S-S-S-T-P-G-K-T-Q-L-I-N-Y-F-E-T-I-W-K-R-G-E-E-R-I-P-L-W-L-V-D-L-P-G-F-G-Y-A-K-V-S-K-E-M-R-K-D-W-G-E-K-L-I-H-F-L-Q-E-R-R-S-I-K-L-F-V-Q-L-I-D-A-R-H-P-D-L-A-I-D-A-E-A-W-A-M-I-G-A-I-K-R-G-D-Q-K-V-I-R-V-F-T-K-M-D-K-L-N-R-N-D-Q-K-K-L-Q-Q-R-Y-P-D-A-C-F-T-A-M-L-G-K-E-G-I-A-S-V-R-E-R-V-L-K-D-V-L-G-E-E-A"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-G-I-D-L-V-S-I-E-R-I-E-A-F-I-A-K-H-G-Q-R-G-L-E-R-F-L-L-P-E-E-I-L-L-A-N-K-P-E-T-I-A-G-F-W-A-A-K-E-A-C-S-K-A-L-G-T-G-I-G-A-E-V-G-F-H-D-I-R-L-F-K-N-P-K-G-A-P-L-L-E-L-S-P-R-V-K-D-R-F-E-I-D-S-C-A-L-S-I-T-H-D-K-G-F-A-I-A-V-V-A-M-E-K-R-R-A"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-N-I-Q-Q-G-K-V-W-K-F-G-E-N-I-D-T-D-L-I-I-A-A-R-Y-L-N-T-S-D-P-Q-V-L-A-S-H-V-M-E-D-A-R-P-D-F-L-Q-H-F-T-K-G-D-F-I-V-A-G-E-N-F-G-C-G-S-S-R-E-H-A-P-V-A-L-K-T-A-G-V-S-A-V-I-A-K-S-F-A-R-I-F-Y-R-N-S-F-N-T-G-L-P-I-L-E-V-K-E-T-D-E-I-R-E-G-D-T-L-E-V-D-M-A-Q-G-T-I-K-N-L-T-R-N-Q-T-Y-A-F-K-P-I-P-P-F-M-M-E-L-L-E-S-G-G-L-I-E-H-A-K-A-K-I-A-Q-G-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-E-F-L-V-E-K-I-G-M-S-R-T-I-S-V-P-S-T-P-V-T-L-L-K-V-K-D-A-K-V-C-E-V-L-G-N-G-K-A-L-V-A-Y-A-Q-G-K-D-A-N-K-A-I-E-G-Q-Q-K-K-Y-N-L-S-K-E-F-N-R-F-A-T-L-E-V-A-N-G-E-A-G-D-Q-D-V-A-P-L-A-Q-A-V-R-V-K-V-S-L-Q-T-K-G-R-G-F-T-G-V-M-K-R-W-N-F-A-G-G-P-A-A-H-G-H-R-F-K-R-R-T-G-S-I-G-N-R-E-W-P-G-R-V-Q-P-G-K-K-M-A-G-Q-Y-G-N-E-K-V-T-V-Q-N-E-I-V-S-F-D-A-E-N-K-I-L-V-L-K-G-S-I-P-G-F-N-G-A-F-G-R-I-K-V-V-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-A-D-I-T-D-I-K-S-I-M-Y-T-E-K-S-L-Q-I-Q-E-S-G-V-L-V-V-Q-T-S-P-K-V-S-K-N-Q-L-K-E-V-F-K-E-Y-F-G-F-T-P-V-R-V-N-S-L-R-Q-A-G-K-I-K-R-F-R-G-V-E-G-K-R-A-S-F-K-K-F-Y-V-K-L-P-E-G-A-K-I-E-S-L-A-V"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-I-K-K-G-P-F-I-D-D-H-L-M-K-K-V-L-K-S-K-E-T-K-D-N-K-P-I-K-T-W-S-R-R-S-T-I-V-P-D-M-I-G-L-T-L-N-V-H-N-G-R-A-F-V-P-V-Y-V-T-E-N-H-V-G-Y-K-L-G-E-F-A-P-T-R-T-F-K-G-H-K-G-S-V-Q-K-K-I-G-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-K-A-L-L-R-Y-I-R-L-S-P-T-K-A-R-L-V-A-R-E-V-Q-G-M-N-A-E-L-A-I-A-S-L-E-F-M-P-N-K-A-A-K-V-I-S-K-V-I-A-S-A-V-A-N-G-G-M-G-A-E-N-A-V-V-K-S-C-R-V-D-A-G-P-V-L-R-R-F-T-P-R-A-R-G-R-A-T-P-I-R-K-P-T-S-H-V-F-V-E-V-V-E-Q-S-K-D-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-F-R-K-Q-M-K-G-R-N-R-G-K-S-F-R-G-N-S-L-A-F-G-D-I-G-I-K-A-T-E-H-G-R-I-D-S-R-Q-I-E-A-A-R-I-A-M-T-R-H-I-K-R-A-G-K-I-W-I-R-V-F-P-D-K-P-L-T-A-K-P-L-E-T-R-M-G-K-G-K-G-S-V-D-K-W-V-M-N-I-Q-P-G-R-I-V-Y-E-M-A-G-I-E-E-E-L-A-R-E-A-L-A-L-A-Q-S-K-L-P-F-K-T-K-I-V-T-S-E-S-E-N-E-I-Y"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-N-E-Q-A-H-K-R-V-I-Q-G-K-V-V-T-K-A-G-D-K-S-V-T-I-L-V-E-R-R-V-T-H-P-K-Y-R-K-I-V-K-R-F-K-K-Y-I-V-H-D-E-S-N-A-V-K-V-G-D-M-I-E-A-I-E-C-R-P-L-S-K-R-K-S-F-S-L-H-K-V-L-S-V-G-V-E-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-S-F-T-R-L-T-V-A-D-N-S-G-A-K-E-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-T-V-G-D-V-I-I-A-S-V-K-K-A-L-P-N-G-K-I-K-K-G-Q-V-V-K-A-V-V-V-R-T-K-K-E-V-Q-R-D-N-G-S-L-I-R-F-D-D-N-A-A-V-I-L-D-N-K-R-E-P-V-G-T-R-I-F-G-P-V-G-R-E-V-R-Y-A-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-V-K-F-Q-I-K-K-G-D-K-V-Q-V-I-A-G-D-D-K-G-K-V-A-E-V-I-K-V-M-P-K-S-S-Q-V-I-V-A-G-C-K-V-A-K-K-S-V-K-P-S-E-Q-N-P-K-G-G-F-V-N-K-E-M-P-I-H-I-S-N-V-K-K-V-E-A"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-Y-Q-L-K-K-L-Y-N-E-E-L-K-A-K-L-S-E-E-L-G-I-K-N-P-M-L-L-P-K-L-E-K-I-V-I-S-V-G-A-G-D-H-A-K-D-T-K-V-M-Q-N-I-A-D-T-I-S-L-I-A-G-Q-K-A-V-I-T-I-A-K-K-S-V-A-G-F-K-M-R-E-G-M-P-M-G-V-K-V-T-L-R-G-N-Q-M-Y-N-F-L-E-K-L-I-S-I-A-L-P-R-V-K-D-F-R-G-V-P-R-N-G-F-D-G-R-G-N-Y-S-F-G-L-N-E-Q-L-M-F-P-E-V-V-Y-D-D-I-M-V-S-H-G-M-N-I-T-M-V-T-T-T-N-N-D-K-E-A-F-K-M-L-E-L-F-G-M-P-F-A-K-G-R-V-N-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-N-D-I-I-A-D-S-L-T-R-I-R-N-A-A-M-R-R-L-D-Y-T-T-L-Y-Y-A-K-I-V-V-S-I-L-E-V-F-L-A-K-G-F-I-E-S-Y-K-V-I-D-K-D-G-K-Q-S-I-N-V-V-L-K-Y-D-E-K-G-R-S-V-I-S-E-I-K-R-I-S-K-S-G-R-R-V-Y-K-G-R-D-E-L-K-R-F-K-N-G-Y-G-T-I-V-V-S-T-S-K-G-V-I-G-N-E-E-A-Y-K-A-N-V-G-G-E-A-L-C-S-I-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-R-P-I-S-I-P-S-G-V-D-A-K-I-E-G-S-K-I-V-F-T-K-G-K-Q-E-K-V-L-E-T-Y-G-R-V-G-L-E-I-A-N-G-E-L-V-L-K-L-G-G-E-D-A-Q-S-K-A-Y-W-G-T-Y-R-A-L-A-N-N-I-V-I-G-L-S-A-G-F-T-K-Q-L-E-I-N-G-V-G-Y-K-A-A-V-K-G-S-V-L-E-L-A-L-G-F-S-H-P-V-N-Y-E-I-P-E-G-V-E-I-A-V-E-K-N-V-I-T-I-K-G-S-D-K-Q-Q-I-G-Q-I-A-A-E-I-R-E-F-R-P-P-E-P-Y-K-G-K-G-V-K-Y-S-D-E-T-I-I-R-K-A-G-K-T-S-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-L-E-K-V-L-K-R-K-N-A-L-R-A-K-R-K-L-R-V-R-G-K-I-F-G-T-A-Q-K-P-R-V-S-L-F-R-S-N-R-Y-L-Y-A-Q-A-I-N-D-E-S-G-L-T-L-A-S-V-D-G-K-K-L-G-L-G-N-N-K-E-E-A-K-K-I-A-A-S-F-A-A-S-L-Q-E-A-G-I-K-E-V-V-F-D-R-N-G-Y-L-Y-H-G-V-V-A-S-F-A-D-S-L-R-E-N-G-I-G-L"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-E-I-N-R-D-E-F-K-E-V-V-V-N-I-G-R-V-T-K-V-V-K-G-G-R-R-F-R-F-N-A-L-V-V-V-G-N-K-N-G-L-V-G-F-G-L-G-K-A-K-E-V-P-D-A-I-K-K-A-V-D-D-A-F-K-N-I-I-K-V-N-V-K-G-T-T-I-A-H-D-I-E-H-K-Y-N-A-S-K-I-L-L-K-P-A-S-E-G-T-G-V-I-A-G-G-S-A-R-P-V-I-E-L-A-G-I-K-D-I-L-T-K-S-L-G-S-N-N-P-Y-N-V-V-R-A-T-I-D-A-L-S-R-I-K-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-L-E-N-L-K-P-A-Q-G-S-T-K-D-R-K-R-V-G-R-G-Q-G-S-G-M-G-K-T-S-T-R-G-G-K-G-Q-T-A-R-T-G-Y-K-A-K-R-G-F-E-G-G-Q-Q-P-L-Q-R-R-L-P-K-V-G-F-T-T-Q-I-A-K-P-Y-V-I-N-V-E-K-I-T-K-V-A-E-L-A-E-I-T-L-D-S-I-A-S-V-H-K-F-P-A-S-T-L-K-I-K-L-I-G-K-G-A-S-E-L-A-S-K-I-K-D-E-R-I-T-T-S-G-R-A"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-E-V-D-G-K-V-I-E-A-L-P-N-A-T-F-R-V-E-L-D-N-K-H-V-I-L-C-H-I-A-G-R-M-R-M-H-Y-I-K-I-L-P-G-D-R-V-K-I-E-L-T-P-Y-S-L-D-K-G-R-I-T-F-R-Y-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-L-P-K-K-K-R-I-E-Y-A-L-T-Y-I-Y-G-I-G-L-K-T-S-R-D-I-L-S-A-V-N-I-S-L-D-K-R-V-Q-E-L-S-E-D-E-V-S-L-I-S-K-K-I-Q-E-S-Y-A-V-E-G-D-L-R-K-K-V-T-M-D-I-K-A-L-M-D-L-G-S-Y-R-G-L-R-H-R-K-G-L-P-V-R-G-Q-T-T-K-N-N-A-R-T-R-K-G-K-R-K-T-V-G-S-A-S-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-R-K-V-T-N-K-K-R-V-V-K-K-N-I-A-R-G-I-I-H-I-A-A-T-F-N-N-T-S-V-T-I-T-D-E-M-G-N-V-I-C-W-S-T-A-G-A-L-G-F-K-G-S-K-K-S-T-P-Y-A-A-Q-Q-A-V-E-D-A-V-V-K-A-K-E-H-G-I-K-E-L-G-I-K-V-Q-G-P-G-S-G-R-E-T-A-V-K-S-L-G-S-I-E-G-I-K-V-L-W-F-K-D-V-T-P-L-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-S-V-L-D-E-N-Q-K-Q-F-L-L-D-S-I-R-N-I-P-D-F-P-K-P-G-I-Q-F-K-D-I-T-T-L-L-N-D-P-K-A-F-G-F-L-I-D-F-L-T-D-R-Y-A-R-F-E-L-D-Y-V-A-G-I-E-S-R-G-F-I-F-G-A-A-L-A-A-K-L-E-V-G-F-V-P-I-R-K-K-G-K-L-P-S-T-T-I-A-E-K-Y-S-L-E-Y-G-F-D-E-V-E-I-H-I-D-A-F-R-E-K-E-G-S-R-V-L-L-I-D-D-L-I-A-T-G-G-T-A-E-A-A-V-K-L-I-Q-S-A-K-G-H-C-V-E-A-C-F-L-L-N-L-E-E-L-G-G-A-K-K-V-S-N-L-A-P-L-Y-T-L-L-D-I"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-L-L-T-K-E-V-K-G-L-G-K-A-G-E-I-H-E-V-K-D-G-Y-G-R-N-F-L-V-G-K-G-M-A-E-I-A-T-N-E-V-I-N-R-W-K-A-E-Q-K-R-R-A-E-K-E-A-Q-E-L-E-R-L-K-N-V-A-K-E-L-A-S-V-T-L-K-I-V-Q-K-V-G-A-N-G-S-L-Y-G-A-I-T-K-E-D-L-S-A-A-L-M-A-Q-K-G-I-E-V-D-K-K-S-F-E-L-K-T-P-I-K-S-T-G-I-Y-E-I-E-V-K-L-G-H-G-I-H-A-E-L-K-I-D-V-E-G-S-N-V"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-Y-S-M-S-D-L-K-K-G-L-K-V-E-I-E-G-V-P-Y-K-I-V-E-Y-Q-H-V-K-P-G-K-G-A-A-F-V-R-V-K-M-K-S-F-F-D-G-R-V-L-E-K-T-F-H-A-G-D-K-C-E-E-P-N-L-Q-E-K-N-M-Q-Y-L-Y-H-D-G-D-H-F-Q-F-M-D-V-E-S-Y-E-Q-I-A-L-S-D-E-Q-V-G-D-V-A-K-W-M-T-D-G-M-T-V-S-I-L-F-H-N-N-K-A-I-S-V-D-V-P-Q-V-V-E-L-K-I-T-E-T-P-P-N-F-K-G-D-T-S-S-G-S-K-K-P-A-T-L-E-T-G-A-V-I-Q-I-P-Y-H-V-L-E-G-D-V-V-R-V-N-T-E-L-G-E-Y-I-E-K-V-K"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-I-E-L-T-A-L-A-I-A-L-S-M-D-A-V-A-V-S-I-A-L-G-S-K-C-E-E-E-I-R-Q-L-A-L-K-A-G-G-F-F-G-V-A-Q-M-V-M-P-L-L-G-F-Y-L-G-V-Q-L-H-D-Y-I-G-G-I-H-H-W-V-A-L-G-V-L-G-F-L-G-L-K-M-I-R-E-A-T-Q-G-E-K-E-L-A-L-S-S-H-P-S-S-S-K-L-L-L-L-A-F-V-T-S-L-D-A-M-A-A-G-L-T-L-T-L-L-G-L-P-L-W-F-C-L-L-F-I-G-G-S-T-F-L-L-S-F-G-G-V-H-L-G-R-K-S-G-T-Y-L-E-E-K-A-E-Y-L-G-G-I-I-L-I-L-I-G-V-K-I-F-I-E-H-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-D-S-A-I-K-L-E-I-I-S-K-F-A-R-G-E-K-D-T-G-S-P-E-V-Q-V-A-L-L-S-R-R-I-S-D-L-T-E-H-L-K-V-N-V-K-D-H-A-S-R-L-G-L-L-K-L-V-A-Q-R-K-H-L-L-K-Y-L-K-K-T-D-Y-A-K-Y-S-E-L-I-S-T-L-G-I-R-D-R"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-R-K-V-I-A-N-N-K-K-A-L-F-D-F-H-I-L-E-R-L-E-A-G-I-A-L-S-G-S-E-V-K-A-I-R-A-G-R-V-N-L-K-D-S-F-V-K-I-I-K-G-E-A-F-L-L-N-A-H-I-S-Y-L-E-T-T-N-P-H-Y-K-P-D-E-R-R-P-R-K-L-L-L-H-R-K-Q-I-D-K-L-T-G-S-V-S-T-E-G-M-T-L-V-T-L-S-I-Y-F-N-E-R-N-R-A-K-A-E-I-A-L-A-K-G-K-N-L-H-D-K-R-E-T-L-K-K-R-I-L-D-R-E-V-K-A-A-L-K-E-H"} +{"text": "### FUNCTION Specifically methylates the N7 position of guanine in position 527 of 16S rRNA ### SEQUENCE -M-S-S-L-K-H-Q-L-K-T-Y-H-I-P-F-D-D-Q-M-L-E-R-L-E-R-Y-T-A-L-L-L-E-W-N-R-A-H-N-L-T-G-A-K-N-S-Q-E-V-E-E-H-L-I-D-S-L-Y-P-L-R-F-L-P-P-F-D-S-C-A-D-I-G-T-G-A-G-F-P-G-L-I-L-A-I-A-L-P-K-S-H-F-D-L-I-E-P-L-K-K-R-V-A-F-L-H-Y-C-V-M-E-L-G-L-S-N-V-S-I-H-A-K-R-I-E-A-L-T-L-E-A-P-D-L-I-T-S-R-A-V-T-S-T-Q-T-L-L-S-L-A-R-P-L-I-A-P-H-T-S-I-L-F-Y-K-G-E-R-V-L-G-E-I-Q-E-E-E-G-Y-T-I-T-P-F-K-Q-R-R-Y-L-F-K-Q-G-V"} +{"text": "### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate with acetyl coenzyme A ### SEQUENCE -M-F-R-P-P-S-I-K-D-A-K-K-I-W-E-L-I-G-R-C-K-P-L-D-I-N-S-P-Y-C-Y-A-L-I-G-R-D-F-F-D-S-S-I-V-Y-E-E-E-G-R-I-K-G-V-V-I-G-Y-L-R-P-R-A-P-E-R-L-F-V-W-Q-V-A-I-E-A-K-S-R-G-K-G-I-A-K-R-A-I-E-A-I-L-K-N-L-E-R-K-G-H-C-I-Q-A-I-E-A-T-Y-T-P-S-N-L-A-S-K-A-L-F-H-A-L-G-R-E-W-K-V-V-W-I-E-E-N-F-L-E-G-A-L-L-S-A-Q-E-A-H-E-E-E-W-L-I-T-L-P-F-S-S-E-A-L-G-V-Q-G-A-N-H-A-N-L"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-T-G-T-V-R-R-Q-R-H-K-K-V-L-K-L-A-R-G-F-Y-S-G-R-R-K-H-F-R-K-A-K-E-Q-L-E-R-S-M-Y-Y-A-F-R-D-R-K-Q-K-K-R-D-F-R-S-L-W-I-T-R-I-N-A-A-C-R-I-N-E-I-S-Y-S-R-F-M-H-G-L-K-L-A-N-I-E-L-D-R-K-I-L-A-D-M-A-M-N-E-P-A-N-F-A-K-I-V-E-A-A-K-K-A-L"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-K-N-N-D-T-T-L-L-N-E-E-I-R-F-P-E-V-R-C-L-G-D-E-G-T-Q-Y-G-V-V-S-S-S-E-A-L-K-I-A-Q-D-L-G-L-D-L-V-L-I-A-P-E-A-K-P-P-V-C-K-I-M-D-Y-G-K-F-R-Y-Q-Q-E-K-K-Q-K-E-A-K-K-K-Q-K-Q-I-E-I-K-E-I-K-L-S-V-K-I-A-Q-N-D-V-N-Y-K-V-K-H-A-K-E-F-L-E-E-D-K-H-V-R-F-R-V-F-L-K-G-R-E-M-S-E-P-Q-S-G-V-E-V-L-K-R-V-W-E-L-V-E-D-I-A-I-M-D-K-E-P-K-P-E-G-R-Y-V-N-M-T-V-I-P-K-P-K-K-V-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-K-S-A-E-K-R-I-R-Q-T-L-K-R-T-E-R-N-R-Y-Y-R-T-R-I-K-N-I-T-K-A-V-K-E-A-V-A-S-N-D-A-T-K-A-E-E-A-L-K-V-A-N-K-D-L-H-K-F-V-S-K-G-I-L-P-K-N-T-A-A-R-K-V-S-R-L-H-A-S-V-K-K-L-S-A-Q-I-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-S-E-L-K-K-M-K-I-R-L-L-K-L-H-P-N-A-V-I-P-A-Y-Q-S-A-G-A-A-G-F-D-L-C-C-V-E-S-L-E-I-P-P-L-G-R-A-L-V-S-T-G-L-A-L-A-L-E-E-G-Y-E-L-Q-I-R-P-R-S-G-L-A-L-K-H-G-I-T-V-L-N-T-P-G-T-V-D-S-D-Y-R-G-E-I-K-V-I-L-I-N-L-G-A-E-S-F-S-I-Q-A-G-D-R-I-A-Q-G-V-V-S-R-L-S-I-A-E-L-C-E-V-E-S-L-D-E-T-A-R-G-A-G-G-F-G-S-T-G-K-S"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-Q-K-E-P-M-T-I-Y-G-Y-E-K-L-Q-R-E-L-K-E-L-K-E-V-E-R-P-Q-I-V-K-E-I-D-I-A-R-G-H-G-D-L-K-E-N-A-E-Y-H-A-A-K-E-R-Q-L-F-I-E-A-R-I-N-E-L-S-E-I-L-S-R-T-Q-V-V-D-P-A-T-I-T-H-E-K-I-S-F-G-S-T-F-K-V-M-D-L-D-T-E-F-V-Y-E-Y-T-I-V-G-A-P-E-S-N-P-D-R-G-F-I-S-F-Y-S-P-L-A-R-Q-L-I-G-K-V-P-G-D-E-I-N-A-K-L-P-N-G-E-I-D-Y-E-V-L-E-V-Y-Y-K-E-I-S-F-E"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-I-F-D-D-I-K-E-V-V-V-E-Q-L-N-V-N-P-E-E-V-K-E-E-S-K-F-V-E-D-L-G-A-D-S-L-D-V-V-E-L-V-M-A-L-E-E-K-F-N-I-E-I-P-D-E-E-A-E-K-I-A-T-V-G-D-V-V-R-Y-I-E-T-N-K"} +{"text": "### FUNCTION Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis ### SEQUENCE -M-Y-V-A-I-E-G-V-D-T-C-G-K-S-T-Q-I-A-L-L-K-R-R-F-P-G-A-I-F-T-K-E-P-G-G-T-A-L-G-M-K-L-R-E-L-L-L-G-G-E-A-K-S-A-K-A-E-L-L-L-F-L-A-D-R-A-E-H-M-E-L-V-I-K-P-A-L-D-K-L-L-F-S-D-R-S-L-I-S-G-M-A-Y-A-K-G-W-D-E-L-W-L-K-S-L-N-L-F-A-T-E-G-I-V-P-D-K-V-V-I-L-E-L-T-A-K-E-L-S-Y-R-L-S-Q-K-S-H-D-S-I-E-S-R-G-V-E-Y-L-L-E-L-Q-E-R-I-K-Q-M-T-A-L-L-G-I-P-S-L-T-L-S-A-S-L-S-P-E-E-I-H-G-R-I-V-S-G-F-V-L-K-G"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-R-N-R-Y-I-E-S-F-E-K-A-Q-I-A-D-K-N-I-P-Q-F-K-A-G-D-T-L-R-V-G-V-K-I-Q-E-G-D-K-T-R-V-Q-N-F-E-G-I-C-I-S-V-R-G-T-G-T-G-K-T-F-T-I-R-K-M-G-A-N-N-V-G-V-E-R-I-F-P-L-Y-S-D-S-L-E-S-V-T-L-L-R-V-G-R-V-R-R-A-K-L-Y-Y-L-R-D-R-S-G-K-S-A-R-I-K-E-L-R-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-R-E-L-V-A-K-R-Y-A-K-A-L-V-E-A-L-G-E-D-R-L-A-S-T-L-E-W-L-K-G-S-E-S-A-F-G-T-E-A-F-Q-E-M-L-A-S-P-Q-I-S-K-T-L-K-G-Q-V-V-L-D-V-L-G-D-G-E-A-K-L-L-N-F-I-K-V-L-A-D-K-N-R-L-E-L-I-P-D-V-C-K-E-L-E-K-S-I-A-A-T-R-N-E-Y-V-A-V-L-T-T-Q-E-A-F-D-D-K-T-L-K-A-I-E-E-T-L-A-K-K-L-Q-A-K-L-V-L-S-Q-K-R-E-E-F-E-G-V-K-L-V-V-E-D-L-G-V-E-V-S-F-S-R-E-R-F-I-N-D-L-K-N-H-I-L-K-A-F"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-G-K-Y-F-I-P-C-L-L-L-P-T-M-M-L-A-S-G-G-G-G-E-T-D-I-V-E-R-T-I-N-F-V-I-F-I-A-I-F-Y-Y-L-A-A-D-K-I-K-A-I-F-V-A-R-Q-E-S-I-A-A-E-L-E-K-V-Q-E-K-L-K-E-S-K-K-A-K-E-Q-A-Q-K-R-F-E-E-S-K-R-M-A-E-D-V-I-L-T-A-K-K-E-V-V-L-L-T-Q-K-V-E-D-S-T-K-G-D-I-E-N-L-I-R-Q-Y-N-D-S-M-E-F-E-K-R-K-A-E-R-A-I-I-D-E-I-L-A-E-L-F-E-S-D-A-T-K-L-D-K-S-A-Y-S-E-I-L-L-K-K-V-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-K-N-G-G-K-Q-Y-K-V-Q-E-G-D-I-V-L-F-D-K-M-S-L-E-P-K-S-K-V-E-L-N-E-V-L-A-L-C-K-D-D-N-L-I-L-G-T-P-F-V-E-G-A-K-I-E-I-E-V-I-N-E-D-R-A-K-K-V-V-T-F-K-K-R-R-R-K-D-S-K-T-K-R-G-F-R-R-D-F-T-R-V-R-I-L-K-I-A-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-D-N-P-A-N-A-E-P-Q-E-E-E-V-S-L-E-S-Q-P-S-T-P-E-S-G-S-D-G-S-K-E-A-E-L-E-A-K-I-K-E-L-E-D-S-Y-L-R-V-H-A-D-F-E-N-T-K-K-R-L-E-R-E-K-F-Q-A-L-E-Y-A-Y-E-K-I-A-K-D-L-L-P-I-V-D-T-L-E-I-A-L-K-S-A-N-E-V-S-G-E-E-S-E-L-Q-A-K-F-K-E-G-L-E-L-T-L-D-N-F-S-K-V-L-Q-R-H-G-I-E-M-I-A-C-E-G-E-F-D-P-H-L-H-E-C-I-M-Q-V-P-S-P-S-H-Q-E-G-E-I-V-Q-V-F-Q-K-G-Y-R-Y-K-E-R-V-L-R-P-A-M-V-S-I-A-K-S-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-R-R-K-A-P-V-R-E-V-L-G-D-P-I-Y-G-N-K-V-V-T-K-F-V-N-K-M-M-Y-D-G-K-K-S-V-A-E-K-I-I-Y-A-T-F-D-R-I-E-E-K-T-K-E-K-G-I-E-V-F-E-K-A-L-E-R-V-R-P-M-V-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-A-T-R-Q-Q-S-L-S-I-R-W-L-L-E-A-A-R-K-R-N-E-R-T-M-V-D-R-L-A-N-E-L-I-D-A-A-N-D-R-G-S-A-F-K-K-K-E-D-V-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-I-R-K-E-R-K-K-A-I-K-K-S-K-S-P-A-L-V-N-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-V-R-L-T-S-G-F-E-V-I-S-Y-I-P-G-E-G-H-N-L-Q-E-H-S-I-V-L-I-R-G-G-R-V-K-D-L-P-G-V-K-Y-H-I-I-R-G-A-L-D-T-A-G-V-Q-K-R-N-V-S-R-S-K-Y-G-A-K-K-G-K-A-G-A-A-P-T-T-G-K-K-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-I-T-K-E-E-L-L-D-Y-I-G-G-L-S-V-L-E-L-S-E-L-V-K-A-F-E-E-K-F-G-V-S-A-A-P-T-V-V-A-G-A-G-A-G-V-A-A-A-A-V-E-E-K-T-E-F-D-V-I-L-L-D-G-G-E-K-K-I-N-V-I-K-V-V-R-E-L-T-G-L-G-L-K-E-A-K-D-A-V-E-K-T-P-T-T-I-K-E-G-A-N-K-D-D-A-A-A-M-K-A-K-L-E-E-A-G-A-K-V-E-I-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-T-K-T-E-K-T-Q-I-I-E-T-L-T-A-E-F-K-A-S-S-A-I-A-V-C-D-Y-K-G-L-T-V-R-Q-F-E-A-L-R-R-A-A-R-D-N-G-A-K-V-Q-V-V-K-N-T-L-A-G-I-A-L-E-N-A-D-A-K-G-L-E-L-K-E-T-N-V-F-V-W-S-D-D-Q-I-A-L-S-K-T-I-M-K-F-A-E-T-S-N-E-K-F-K-V-K-F-G-Y-Y-E-G-S-V-V-D-A-A-H-I-E-T-V-S-K-L-P-S-R-D-E-L-I-G-M-L-L-S-V-W-T-A-P-A-R-Y-F-V-T-A-L-D-N-L-K-K-Q-K-E-E-N"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-V-A-L-K-G-N-I-E-K-K-E-P-T-R-L-W-L-E-V-G-G-V-T-Y-E-I-F-I-S-I-H-T-S-A-A-L-G-E-K-E-A-R-L-L-I-T-H-L-I-R-E-E-A-W-S-L-Y-G-F-A-E-E-A-E-K-R-V-F-D-T-L-I-K-I-N-G-V-G-P-K-A-A-L-A-I-L-S-T-Y-T-P-P-T-F-A-Q-I-I-Q-A-Q-D-V-K-A-L-Q-R-V-P-G-I-G-P-K-S-A-G-R-I-M-V-E-L-A-G-F-S-L-S-L-Q-E-G-S-K-A-S-T-P-P-V-F-E-E-S-R-L-A-L-E-S-L-G-F-K-S-E-L-I-A-K-A-L-Q-N-I-Q-A-T-T-T-Q-E-I-I-K-E-A-L-K-K-L-Q-T-L-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-E-L-N-E-V-Y-Q-Y-T-K-E-H-M-E-K-T-I-D-A-M-K-R-D-F-A-T-L-R-T-G-K-V-S-T-A-I-V-E-P-I-R-V-D-Y-Y-G-T-P-T-P-L-S-Q-V-G-S-V-I-A-S-D-A-T-T-L-V-I-S-P-W-E-K-N-L-L-K-G-I-E-K-A-I-Q-E-A-N-I-G-V-N-P-N-N-D-G-D-V-I-K-L-F-F-P-P-M-T-S-E-Q-R-K-E-I-A-K-D-A-K-A-L-G-E-K-A-K-V-A-V-R-N-I-R-K-E-S-N-D-K-I-K-K-L-E-K-D-K-L-I-T-E-D-Q-S-K-K-A-H-D-E-V-Q-K-Y-T-D-D-Y-V-K-K-I-D-D-M-V-K-S-K-E-E-E-I-L-K-V"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-F-K-P-L-G-Q-R-V-L-V-E-R-L-E-E-D-T-K-T-A-S-G-I-I-I-P-D-N-A-K-E-K-P-L-M-G-T-V-K-A-L-S-E-E-V-A-K-E-G-L-L-K-A-G-S-Q-V-V-F-A-K-Y-S-G-T-D-V-K-L-E-G-K-E-Y-L-I-L-K-V-E-D-L-L-G-T-I-E"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-A-T-R-A-Q-A-R-E-A-V-V-S-L-L-Y-A-Y-D-M-G-N-T-E-I-R-K-F-A-I-E-L-L-E-E-K-R-I-K-N-R-Q-Q-E-F-A-L-E-L-F-D-G-T-I-A-H-L-G-E-I-D-E-E-I-K-K-H-L-K-E-W-D-F-S-R-I-G-D-M-E-R-A-I-L-R-L-G-T-F-E-I-V-Y-S-G-V-D-R-A-V-I-I-N-E-A-V-E-L-S-K-T-F-G-N-D-N-S-P-R-F-V-N-G-V-L-D-A-L-R-P-D-L-K-K-G"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-N-V-I-E-G-K-L-N-L-T-G-N-E-R-V-A-V-I-A-S-R-F-N-H-L-I-T-D-R-L-V-E-G-A-R-D-S-F-V-R-H-G-G-K-D-E-H-L-D-L-I-L-V-P-G-A-F-E-L-P-F-A-L-E-K-V-L-A-Q-G-D-Y-D-G-V-C-C-L-G-A-I-I-R-G-S-T-P-H-F-D-Y-V-S-A-E-A-T-K-G-I-A-N-V-T-L-K-Y-G-A-A-V-T-F-G-V-L-T-T-D-N-I-E-Q-A-I-E-R-A-G-T-K-V-G-N-K-G-F-E-A-M-T-G-L-I-E-M-M-N-L-Y-K-N-I-G-A"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-L-Y-D-V-Q-K-I-K-E-I-L-P-H-R-F-P-F-L-L-V-D-R-V-T-A-L-T-S-E-E-S-I-E-A-Y-K-N-I-T-I-N-E-E-V-F-Q-G-H-F-P-I-K-P-V-Y-P-G-V-L-V-I-E-G-M-A-Q-A-G-G-V-L-A-F-V-S-M-F-G-E-E-A-S-N-H-D-E-K-I-V-Y-F-M-S-I-D-K-A-K-F-R-V-P-V-T-P-G-D-K-L-V-Y-R-L-N-V-L-K-H-K-G-S-I-W-I-L-E-G-R-A-Y-V-D-D-K-L-V-A-E-A-E-L-K-A-M-V-A-D-K-E-K"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-M-K-K-I-D-V-K-I-L-D-P-R-I-G-E-E-F-P-L-P-T-Y-A-T-P-G-S-A-G-L-D-L-R-A-C-L-D-N-A-V-E-L-A-P-G-Q-T-E-L-L-P-T-G-L-A-I-H-I-G-D-E-Q-L-A-A-V-I-L-P-R-S-G-L-G-H-K-H-G-V-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-Q-L-M-V-S-V-W-N-R-G-D-K-A-F-T-I-Q-P-G-E-R-I-A-Q-I-V-F-V-P-V-V-Q-A-E-F-N-L-V-E-D-F-E-T-S-E-R-G-S-G-G-F-G-H-S-G-R-Q"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-K-R-K-E-V-E-S-K-S-A-G-G-I-V-L-T-G-T-A-A-G-K-S-T-R-G-E-V-L-A-V-G-N-G-R-I-L-E-S-G-D-V-K-A-L-C-V-K-V-G-D-I-V-I-F-N-D-G-Y-G-V-K-S-E-K-I-D-N-E-E-V-L-I-M-S-E-S-D-I-L-A-I-V-E-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-Q-A-V-I-D-V-K-I-L-D-A-R-L-R-D-N-L-P-A-Y-A-T-A-G-S-A-G-L-D-L-R-A-A-T-E-E-T-M-T-I-Q-P-G-E-T-Q-L-V-P-T-G-I-A-I-H-L-S-D-P-G-L-A-A-M-L-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-Q-M-F-V-S-V-W-N-R-G-Q-Q-P-F-R-L-E-P-M-E-R-I-A-Q-M-V-I-V-P-V-V-Q-A-S-F-N-I-V-D-D-F-D-A-S-D-R-G-A-G-G-F-G-S-T-G-R-G"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-V-L-E-I-L-T-A-P-D-P-R-L-R-V-Q-S-K-E-V-T-D-V-A-A-V-Q-T-L-I-D-D-L-L-E-T-L-Y-E-T-D-N-G-V-G-L-A-A-P-Q-V-G-R-E-E-A-I-V-V-I-D-L-S-E-N-R-D-E-P-L-V-L-V-N-P-K-V-V-S-G-S-N-K-E-M-G-Q-E-G-C-L-S-V-P-D-Y-Y-A-D-V-E-R-Y-T-S-V-V-V-E-A-L-D-R-N-G-K-E-L-R-I-E-T-S-E-F-L-A-I-V-M-Q-H-E-I-D-H-L-S-G-N-L-F-I-D-Y-L-S-P-L-K-Q-Q-M-A-M-K-K-V-K-K-H-N-K-L-R-A-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-D-K-T-L-K-F-T-E-S-H-E-W-V-R-D-N-G-D-G-T-V-T-I-G-I-S-E-H-A-Q-E-M-L-G-D-V-V-F-V-E-L-P-E-L-E-A-E-I-E-A-G-E-S-F-S-L-V-E-S-V-K-A-A-S-D-I-Y-A-P-V-T-G-E-V-V-E-V-N-E-E-L-S-D-S-P-E-L-I-N-E-E-P-Y-E-G-G-W-I-V-K-V-K-L-S-D-P-S-E-L-D-N-L-K-D-A-E-E-Y-L-N-S-I-E-E-D"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-Q-K-T-T-R-T-M-P-A-H-K-H-I-A-L-V-A-H-D-N-Y-K-P-E-L-L-R-W-V-K-E-N-K-E-K-L-Q-S-H-F-L-Y-A-T-G-T-T-G-H-M-L-S-R-E-T-G-L-A-I-K-S-M-I-S-G-P-M-G-G-D-Q-Q-L-G-A-L-I-S-E-G-K-I-D-M-L-I-F-F-W-D-P-L-N-A-V-P-H-D-P-D-V-K-A-L-L-R-I-A-S-V-W-N-I-P-V-A-T-N-R-A-T-A-K-F-L-F-E-S-P-L-L-N-E-E-V-D-V-E-I-P-D-Y-Q-A-Y-L-A-G-R-T"} +{"text": "### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-T-A-P-T-K-M-T-F-F-S-R-F-E-A-D-I-L-A-G-K-K-T-I-T-I-R-D-E-S-E-K-D-Y-Q-P-G-T-T-V-E-V-S-T-L-E-E-G-R-V-F-C-Q-L-K-I-L-S-V-E-P-I-A-F-S-E-L-N-E-F-H-A-E-Q-E-N-M-T-L-A-T-L-K-E-V-I-Q-E-I-Y-P-G-I-E-Q-L-Y-V-I-Q-Y-Q-R-V"} +{"text": "### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-V-G-M-P-K-I-R-R-P-Q-L-V-S-A-T-M-T-V-I-D-R-V-G-L-H-G-A-S-V-S-L-I-S-Q-E-A-G-V-S-S-G-I-I-N-H-Y-F-G-G-K-H-G-L-L-E-E-T-M-R-D-I-L-R-Q-L-S-C-D-A-T-K-R-L-N-S-L-P-K-Q-A-H-M-Q-R-I-N-A-I-L-D-A-N-F-V-G-F-Q-S-E-S-K-V-I-K-T-W-L-A-F-W-S-Y-S-M-H-D-E-A-L-K-R-L-Q-R-V-N-E-K-R-L-L-S-H-L-K-R-E-L-K-A-L-M-S-K-E-Q-A-D-I-V-A-Q-G-I-A-A-L-I-D-G-I-W-L-R-G-A-L-N-P-E-G-I-N-A-N-K-A-R-I-I-I-N-D-Y-L-E-K-Q-L-T-F-Y-S-Q-Q"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-M-N-A-T-L-L-G-Q-A-I-S-F-A-M-F-V-W-F-C-M-K-Y-V-W-P-P-I-M-Q-A-I-E-E-R-Q-K-K-I-A-D-G-L-Q-A-A-E-R-A-A-K-D-L-D-L-A-Q-A-N-A-S-S-Q-L-K-E-A-K-R-T-A-T-E-I-I-E-Q-A-N-K-R-K-A-Q-I-L-D-E-A-R-E-D-A-Q-T-E-R-Q-K-I-L-A-Q-A-E-A-Q-L-E-A-E-R-N-R-A-R-D-E-L-R-K-Q-V-A-T-L-A-V-A-G-A-E-K-I-L-E-R-S-I-D-K-D-A-H-K-D-I-L-D-N-I-T-A-K-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-D-F-T-T-I-A-R-P-Y-A-K-A-A-F-D-F-A-V-E-K-G-Q-L-D-Q-W-G-Q-M-L-S-F-A-A-E-V-A-Q-N-E-Q-I-S-E-L-L-S-G-S-M-S-A-D-K-L-A-E-L-F-I-A-I-C-G-E-Q-V-D-E-F-G-Q-N-L-L-K-V-M-A-E-N-G-R-L-A-A-L-P-D-V-C-T-L-F-F-V-L-K-K-E-H-E-K-E-I-D-V-E-V-I-S-A-T-E-L-S-D-E-Q-C-A-N-I-S-Q-K-L-E-Q-R-L-E-R-K-V-K-L-N-C-S-V-D-E-A-L-L-G-G-V-I-I-R-A-G-D-L-V-I-D-N-S-A-R-G-R-L-N-R-L-S-D-A-L-Q-S"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-A-I-T-F-H-L-D-V-V-S-A-E-K-K-I-F-S-G-R-V-E-T-F-Q-V-T-G-S-E-G-E-L-G-I-F-H-G-H-T-P-L-L-T-A-I-K-P-G-M-V-R-I-V-K-L-H-G-E-E-E-F-I-Y-V-S-G-G-I-V-E-V-Q-P-G-T-A-T-V-L-A-D-T-A-I-R-G-E-E-L-D-A-A-K-A-E-E-A-K-R-R-A-K-E-N-I-L-N-Q-H-G-D-M-D-F-A-Q-A-A-S-E-L-A-K-A-I-A-Q-L-R-V-I-E-L-T-K-K-R-R"} +{"text": "### FUNCTION Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide ### SEQUENCE -M-K-V-G-I-I-M-G-S-K-S-D-W-P-T-M-K-L-A-A-E-M-L-D-R-F-G-V-E-Y-E-T-K-V-V-S-A-H-R-T-P-H-L-L-A-E-Y-A-S-T-A-K-E-R-G-L-K-V-I-I-A-G-A-G-G-A-A-H-L-P-G-M-A-A-A-F-T-S-L-P-V-L-G-V-P-V-Q-S-R-A-L-S-G-L-D-S-L-Y-S-I-V-Q-M-P-K-G-I-A-V-G-T-L-A-I-G-E-A-G-A-A-N-A-G-L-L-A-A-Q-I-L-G-T-H-D-E-N-I-M-A-K-V-E-A-F-R-S-E-Q-T-E-S-V-L-A-N-P-N-P-A-E-D"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-S-Q-F-A-I-L-G-F-I-A-L-G-G-A-F-G-A-C-S-R-Y-L-V-S-E-L-C-V-V-L-L-G-R-G-F-P-Y-G-T-L-T-V-N-V-V-G-S-F-I-M-G-L-L-I-A-A-F-E-S-E-L-L-A-T-E-P-W-R-Q-I-I-G-L-G-F-L-G-A-L-T-T-F-S-T-F-S-M-D-N-V-L-L-M-Q-Q-G-A-F-F-K-M-G-L-N-V-V-L-N-V-T-L-S-I-T-A-A-W-V-G-F-Q-L-L-K-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-Q-D-K-K-A-I-V-A-E-V-N-E-A-A-A-G-A-L-S-A-V-V-A-D-S-R-G-V-S-V-D-A-M-T-T-L-R-K-Q-A-R-E-A-G-V-Y-M-K-V-V-R-N-T-L-A-R-R-A-V-E-G-T-Q-Y-E-C-L-T-D-T-F-T-G-P-S-L-I-A-F-S-N-E-H-P-G-A-A-A-R-L-F-K-D-F-A-K-E-N-K-K-F-E-I-K-A-A-A-F-E-G-A-L-T-D-A-E-V-L-A-T-L-P-T-Y-D-E-A-I-A-R-L-M-M-C-L-K-E-A-S-A-G-K-L-V-R-T-I-A-A-I-R-D-Q-K-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-I-T-N-E-Q-I-L-D-A-I-A-E-M-S-V-T-Q-V-V-E-L-I-S-A-M-E-E-K-F-G-V-T-A-A-A-A-V-V-A-G-G-A-A-A-G-A-A-V-E-E-Q-T-E-F-N-V-I-L-A-S-A-G-A-N-K-V-A-V-I-K-A-V-R-G-A-T-G-L-G-L-K-E-A-K-A-L-V-D-G-A-P-A-A-L-K-E-G-V-E-K-A-E-A-E-A-L-K-K-E-L-E-E-A-G-A-T-V-E-I-K"} +{"text": "### FUNCTION Activates ribosomal RNA transcription Plays a direct role in upstream activation of rRNA promoters ### SEQUENCE -M-F-E-Q-N-L-T-S-E-A-L-T-V-T-T-V-T-S-Q-D-Q-I-T-Q-K-P-L-R-D-S-V-K-A-S-L-K-N-Y-L-A-Q-L-N-G-Q-E-V-T-E-L-Y-E-L-V-L-A-E-V-E-Q-P-L-L-D-T-I-M-Q-Y-T-R-G-N-Q-T-R-A-A-T-M-M-G-I-N-R-G-T-L-R-K-K-L-K-K-Y-G-M-N"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-T-V-S-T-N-E-F-K-G-G-L-K-L-M-I-D-S-E-P-C-V-I-L-E-N-E-Y-V-K-P-G-K-G-Q-A-F-N-R-V-K-I-R-K-L-L-S-G-K-V-L-E-K-T-F-K-S-G-D-T-C-E-V-A-D-V-M-D-I-D-L-D-Y-L-Y-S-D-G-E-F-Y-H-F-M-N-N-E-T-F-E-Q-I-A-A-D-A-K-A-V-G-E-N-V-K-W-L-V-E-N-N-T-C-M-L-T-L-W-N-G-N-P-I-A-V-T-P-P-N-F-V-E-L-E-V-I-E-T-D-P-G-L-K-G-D-T-Q-G-T-G-G-K-P-A-T-L-S-T-G-A-V-V-R-V-P-L-F-I-Q-I-G-E-V-I-K-V-D-T-R-S-S-E-Y-V-G-R-V-K"} +{"text": "### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-K-P-N-Y-N-V-D-R-A-P-K-R-S-D-E-P-V-W-W-S-L-F-G-A-G-G-T-W-F-A-M-I-T-P-V-T-V-L-V-L-G-I-L-V-P-M-G-V-I-N-A-E-A-L-S-Y-D-R-V-V-S-F-A-T-S-I-I-G-A-L-F-I-I-A-T-L-A-L-P-M-W-H-A-M-H-R-V-H-H-G-M-H-D-L-K-F-H-T-G-V-V-G-K-I-A-C-Y-A-I-A-G-L-I-S-A-L-A-V-V-F-I-F-M-L"} +{"text": "### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-S-N-R-K-P-Y-V-R-E-V-K-R-T-W-W-K-D-H-P-F-Y-R-F-Y-M-L-R-E-A-T-V-L-P-L-I-L-F-T-L-F-L-T-V-G-L-G-S-L-V-K-G-P-E-A-W-Q-T-W-L-N-F-M-A-N-P-V-V-I-A-I-N-I-V-A-L-L-G-S-L-L-H-A-H-T-F-F-S-M-M-P-Q-V-M-P-I-R-L-K-G-K-P-V-D-K-K-I-I-V-L-A-Q-W-A-A-V-A-F-I-S-L-I-V-L-I-V-V"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-A-E-A-A-P-Q-D-T-Q-Q-H-F-A-I-Q-R-I-F-L-K-D-V-S-F-E-A-P-N-S-P-V-M-F-Q-K-E-W-N-P-D-V-K-L-D-L-D-T-Q-S-R-E-L-G-E-G-V-Y-E-V-I-L-R-L-T-V-T-V-K-N-A-E-E-T-A-F-L-C-E-V-Q-Q-G-G-I-F-T-A-E-K-M-E-A-G-Q-L-A-H-C-L-G-A-F-C-P-N-I-L-F-P-Y-A-R-E-T-I-S-S-L-V-V-K-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-M-N-Y-L-Q-Q-Q-A-A-Q-Q-G-A-E-Q-A"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-S-F-S-D-Q-N-L-I-W-I-D-L-E-M-T-G-L-D-P-D-V-H-K-I-I-E-I-A-S-I-V-T-D-S-E-L-N-I-L-A-E-G-P-V-L-A-I-H-Q-S-E-E-E-L-A-K-M-D-E-W-C-T-N-T-H-T-G-S-G-L-V-E-R-V-R-G-S-Q-I-T-E-Q-E-A-V-E-Q-T-I-A-F-L-E-K-W-V-P-K-G-V-S-P-I-C-G-N-S-I-G-Q-D-R-R-F-L-Y-R-H-M-P-E-L-E-G-Y-F-H-Y-R-Y-I-D-V-S-T-L-K-E-L-T-R-R-W-N-P-E-V-L-K-G-F-S-K-Q-G-T-H-L-A-L-D-D-I-R-E-S-I-A-E-L-K-F-Y-R-Q-T-I-F-K-I"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-I-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-N-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-P-V-S-H-H-S-G-E-R-G-S-D-R-P-S-E-K-S-E-D"} +{"text": "### FUNCTION Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress May require iron for activity ### SEQUENCE -M-Q-L-T-S-F-T-D-Y-A-L-R-T-L-I-Y-L-A-S-L-P-D-N-E-Q-T-N-I-T-D-V-T-E-L-F-G-V-S-R-N-H-M-V-K-V-I-N-R-L-G-Q-L-N-Y-I-Q-T-V-R-G-K-N-G-G-I-R-L-N-R-P-A-K-T-I-L-V-G-E-V-V-R-D-L-E-P-L-D-L-V-N-C-S-V-E-F-C-H-I-T-P-A-C-R-L-K-E-R-L-Y-R-A-K-L-A-F-L-A-E-L-D-D-C-S-I-A-E-L-L-D-D-N-A-E-L-L-I-L-L-Q-K-A"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-S-A-L-R-Y-T-L-V-V-N-G-S-V-Y-G-S-Q-S-A-R-T-A-Y-Q-F-A-T-A-L-I-E-K-G-H-T-L-V-S-V-F-F-Y-Q-D-G-V-T-N-G-T-E-L-T-V-P-A-N-D-E-F-H-L-T-K-A-W-Q-Q-L-A-K-Q-H-N-V-R-L-E-T-C-V-A-A-A-L-R-R-G-V-V-S-Q-S-E-A-S-Q-H-G-L-L-Q-H-N-L-A-E-G-F-E-Q-A-G-L-G-S-L-A-E-A-M-L-T-Q-D-R-V-V-Q-F"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-N-Q-L-V-R-K-P-R-A-K-Q-V-V-K-S-N-V-P-A-L-E-A-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-T-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-A-L-D-C-A-G-V-N-N-R-K-Q-G-R-S-K-Y-G-V-K-R-P-K-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-I-G-Q-R-K-I-L-P-D-P-K-F-K-S-E-L-L-A-K-F-V-N-I-L-M-V-D-G-K-K-S-V-A-E-K-I-V-Y-T-A-L-D-T-M-A-E-K-S-G-K-D-H-L-A-V-F-E-E-A-L-E-N-V-R-P-A-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-P-V-R-R-N-A-L-A-M-R-W-L-V-E-A-A-R-K-R-G-E-K-S-M-A-A-R-L-A-A-E-M-L-D-A-S-D-N-K-G-T-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-F-E-V-L-E-K-L-E-A-K-I-Q-T-A-V-D-T-I-A-L-L-Q-M-E-V-D-E-L-K-E-D-K-A-K-L-E-T-E-A-N-E-L-R-A-Q-R-E-Q-L-E-Q-K-A-Q-Q-T-Q-Q-E-H-A-Q-W-Q-E-R-I-R-A-L-L-G-K-M-E-D-V-E"} +{"text": "### FUNCTION Globally modulates RNA abundance by binding to RNase E and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome Modulates RNA-binding and helicase activities of the degradosome ### SEQUENCE -M-E-Y-N-T-S-A-L-C-D-I-Y-M-D-Q-V-D-V-V-E-P-M-F-S-N-F-G-G-R-A-S-F-A-G-Q-I-T-T-V-K-C-F-E-D-N-A-L-I-R-E-T-L-E-Q-D-G-V-G-R-V-L-L-V-D-G-G-G-S-L-R-R-A-L-L-D-G-E-L-A-A-I-A-E-E-N-E-W-E-G-I-V-V-Y-G-C-V-R-E-V-D-E-L-E-D-M-N-I-G-I-Q-A-L-A-S-I-P-V-S-A-A-M-Q-G-V-G-E-V-D-V-P-V-N-F-G-G-V-T-F-L-P-E-D-Y-L-Y-A-D-T-T-G-I-I-L-S-Q-E-P-L-S-A-D-L-E-E-D-E-E-E-P-E-L-L-D"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-G-I-H-P-E-Y-K-A-V-N-A-T-C-S-C-G-N-S-F-V-F-N-S-T-L-D-K-D-S-I-H-L-D-V-C-D-K-C-H-P-F-Y-T-G-K-Q-R-I-V-D-T-G-G-R-V-D-R-F-N-K-R-F-G-A-L-S-S-G-K-K"} +{"text": "### FUNCTION This regulatory protein, when combined with SAM represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-A-D-W-N-G-E-Y-I-S-P-Y-A-E-H-G-K-K-S-E-Q-V-K-K-I-T-V-S-I-P-L-K-V-L-K-V-L-T-D-E-R-T-R-R-Q-I-N-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-Y-T-G-Q-P-L-P-T-D-E-D-L-R-K-D-R-P-D-D-I-P-T-E-A-K-E-L-M-T-A-M-G-I-E-F-E-A-Y-D-D"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-A-G-M-I-E-R-Y-T-G-S-I-T-E-A-G-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-V-L-M-N-V-E-A-D-Q-A-V-I-D-E-L-E-T-A-F-R-Y-N-D-A-V-L-R-N-M-I-M-R-T-K-A-A-I-T-E-P-S-I-M-L-K-Q-K-E-E-R-A-P-R-R-E-A-E-A-K-E-F-A-A-E"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-T-N-R-M-E-L-S-G-T-V-V-K-D-P-I-R-S-Q-S-P-A-G-I-S-H-C-R-F-W-L-E-H-R-S-V-V-V-E-A-D-L-P-R-Q-V-F-C-R-M-P-V-V-V-S-G-K-G-S-Q-D-I-T-Q-Q-I-V-L-G-S-N-I-K-V-S-G-F-V-A-Y-Q-T-G-R-N-G-V-G-K-L-V-L-H-A-D-D-I-I-H-I"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-F-F-R-R-R-K-F-C-R-F-T-A-E-G-V-Q-E-I-D-Y-K-D-V-A-T-L-K-N-Y-I-T-E-A-G-K-I-V-P-S-R-I-T-G-T-S-A-K-Y-Q-R-Q-L-A-R-A-I-K-R-S-R-Y-L-A-L-L-P-Y-T-D-K-H-Q"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-D-K-I-G-N-L-G-S-L-G-D-T-V-N-V-K-S-G-Y-A-R-N-F-L-I-P-Q-G-K-A-V-M-A-T-K-G-N-V-E-M-F-E-A-R-R-A-E-L-E-A-K-V-A-E-Q-L-A-S-A-E-A-R-A-E-K-V-N-A-L-E-A-V-V-I-A-S-K-A-G-D-E-G-K-L-F-G-S-I-G-T-R-D-I-A-D-A-I-T-A-A-G-V-E-V-V-K-S-E-V-R-L-P-E-G-A-L-R-T-T-G-E-F-E-I-S-V-Q-L-H-S-E-V-F-A-T-V-K-L-Q-V-V-A-E"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-N-K-E-T-K-L-Q-V-E-A-I-K-N-G-T-V-I-D-H-I-P-A-Q-V-G-I-K-V-L-K-L-F-D-M-H-N-S-S-Q-R-V-T-I-G-L-N-L-P-S-S-A-L-G-N-K-D-L-L-K-I-E-N-V-F-I-N-E-E-Q-A-S-K-L-A-L-Y-A-P-H-A-T-V-N-Q-I-E-D-Y-Q-V-V-K-K-L-A-L-E-L-P-E-F-V-S-D-V-F-E-C-P-N-S-N-C-I-T-H-N-E-P-V-A-S-N-F-R-V-F-E-K-K-G-D-V-R-L-K-C-K-Y-C-E-K-V-F-S-R-E-I-V-T-E-R"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-R-T-I-M-A-F-D-F-G-T-K-S-I-G-S-A-I-G-Q-E-I-T-G-T-A-S-P-L-K-A-F-K-A-N-D-G-I-P-N-W-D-E-I-E-K-Q-I-K-E-W-Q-P-N-L-L-V-V-G-L-P-T-D-L-H-G-K-A-L-E-T-I-T-P-R-A-K-K-F-A-Q-R-L-Q-G-R-F-A-L-P-V-E-L-H-D-E-R-L-S-T-T-E-A-R-S-E-L-F-S-M-G-G-Y-K-A-L-S-K-G-N-V-D-C-Q-S-A-V-I-I-L-E-S-W-F-E-A-Q-W-G"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-V-G-L-G-T-D-I-A-E-I-E-R-V-E-K-A-L-A-R-S-G-V-A-F-A-E-R-I-L-S-V-Q-E-M-E-T-F-V-S-L-K-Q-Q-G-R-F-L-A-K-R-F-A-A-K-E-A-A-S-K-A-L-G-T-G-I-A-H-G-V-S-F-Q-D-F-T-I-K-N-D-D-N-G-K-P-Y-L-Q-L-A-G-R-A-A-E-L-A-H-Q-M-G-V-C-H-T-H-L-S-L-S-D-E-R-H-Y-A-V-A-T-V-I-F-E-S"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-L-F-I-L-V-L-T-L-L-F-G-W-L-Q-Y-T-L-W-F-G-K-N-G-V-S-D-Y-Y-T-I-E-S-D-I-E-A-Q-Q-L-V-N-T-K-L-Q-A-R-N-S-E-M-Y-A-E-I-D-D-L-K-Q-G-L-D-A-I-E-E-R-A-R-H-E-L-G-M-L-K-E-G-E-T-F-Y-R-I-V-G-E-E-N-Q"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-H-H-R-F-T-P-P-M-M-N-C-K-D-T-A-I-Q-L-L-S-R-R-D-H-G-Q-Y-E-L-K-Q-K-L-T-L-K-G-Y-A-S-Q-D-I-E-S-A-M-H-F-C-L-E-H-G-Y-L-D-D-L-R-Y-A-K-S-Q-I-R-Q-H-V-G-K-G-H-G-E-R-R-I-R-Q-E-L-S-L-K-Q-V-S-D-S-V-V-E-N-A-F-A-E-E-P-Q-D-W-F-E-L-A-K-S-V-A-M-K-K-F-N-G-V-K-A-K-E-Q-K-E-Y-A-K-Q-V-R-F-L-Q-Y-R-G-F-S-F-E-Q-I-R-Y-A-L-N-D-K-A"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-M-I-G-D-E-V-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-V-N-A-P-K-D-V-S-V-H-R-E-E-I-Y-M-R-I-Q-A-E-K-G-N-V-T-P-G-N-Y"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-T-V-D-H-T-R-M-H-A-P-A-V-R-V-A-K-T-M-Q-T-P-K-G-D-T-I-T-V-F-D-L-R-F-T-A-P-N-K-D-I-L-S-E-K-G-I-H-T-L-E-H-L-Y-A-G-F-M-R-K-H-L-N-G-A-S-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-A-P-S-E-Q-D-V-A-S-A-W-T-A-S-M-E-D-V-L-K-V-E-S-Q-N-K-I-P-E-L-N-E-Y-Q-C-G-T-A-A-M-H-S-L-D-E-A-K-Q-I-A-Q-N-I-L-A-A-G-I-S-V-N-K-N-D-E-L-A-L-P-E-A-M-L-K-E-L-K-V-D"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-M-K-G-K-E-T-M-S-D-E-R-I-V-V-G-K-F-G-S-T-Y-G-I-R-G-W-L-K-V-F-S-Y-T-D-N-A-E-S-L-F-D-Y-S-P-W-Y-V-N-Q-K-G-E-W-V-E-F-K-V-E-S-W-K-R-H-N-K-G-M-V-A-K-L-E-G-L-D-V-R-E-D-A-H-L-L-T-N-L-E-I-A-I-D-P-A-V-L-P-E-L-S-E-D-E-F-Y-W-R-E-L-F-G-M-Q-V-V-T-T-N-G-Y-D-L-G-V-V-T-D-M-L-E-T-G-S-N-D-V-L-V-V-K-A-N-L-K-D-A-F-G-Q-K-E-R-L-I-P-F-L-E-E-Q-V-I-I-K-V-D-R-E-A-Q-R-I-E-V-D-W-D-P-G-F"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-N-I-I-K-A-L-E-Q-E-Q-M-K-Q-D-L-P-K-F-A-P-G-D-T-V-V-V-Q-V-K-V-K-E-G-N-R-E-R-L-Q-A-Y-E-G-V-V-I-A-I-R-N-R-G-L-H-S-A-F-T-V-R-K-I-S-N-G-E-G-V-E-R-T-F-Q-T-H-S-P-V-V-D-S-I-E-V-K-R-R-G-A-V-R-R-A-K-L-Y-Y-L-R-E-R-S-G-K-S-A-R-I-K-E-K-L-A-K-K"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-T-K-I-T-I-V-K-C-P-Q-C-G-T-D-V-E-W-G-E-Q-S-P-H-R-P-F-C-S-K-K-C-Q-M-I-D-F-G-E-W-A-D-E-E-N-A-I-P-G-A-P-D-M-S-D-S-D-G-W-S-E-E-Q-Y"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-D-I-N-L-P-L-S-F-S-D-A-A-A-T-R-V-K-M-L-I-A-E-E-E-N-P-A-L-K-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-S-V-N-E-G-D-T-T-I-E-N-S-G-V-T-L-V-V-D-P-M-S-L-Q-Y-L-I-G-G-V-V-D-Y-T-E-G-L-E-G-S-R-F-F-V-N-N-P-N-A-T-T-T-C-G-C-G-A-S-F-S-V"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-G-L-E-R-Q-L-T-E-M-L-E-S-A-V-V-A-S-G-Y-E-L-V-G-L-E-F-I-R-A-G-E-H-S-T-L-R-I-Y-I-D-H-E-N-G-I-T-V-E-D-C-A-E-V-S-H-Q-V-S-A-V-L-D-V-E-D-P-I-S-V-A-Y-S-L-E-V-S-S-P-G-L-D-R-P-L-F-K-P-A-H-Y-E-Q-F-I-G-Q-E-V-N-V-V-L-K-M-A-V-A-N-R-R-K-W-K-G-E-I-H-S-V-D-G-E-A-I-T-L-T-V-D-G-Q-Q-E-E-F-A-L-S-N-I-S-K-A-N-L-I-P-K-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-K-D-F-S-R-T-Q-R-V-S-Q-Q-L-Q-K-E-L-A-M-I-L-Q-R-E-V-R-D-S-R-L-G-M-V-T-I-S-D-V-E-V-S-R-D-L-A-Y-A-K-V-F-V-T-F-L-C-V-G-E-Q-T-P-E-S-C-L-A-A-L-R-E-H-E-V-H-I-R-M-M-L-G-K-R-I-R-L-R-L-T-P-E-V-R-F-Y-Y-D-N-T-L-V-E-G-M-R-M-S-N-L-V-T-E-V-V-N-K-D-K-I-K-Q-K-D-A-G-R-E-D-E-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-N-A-E-T-K-A-A-I-V-A-D-Y-A-R-G-E-G-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-S-I-N-H-L-Q-G-H-F-Q-A-H-K-G-D-H-H-S-R-R-G-L-L-R-M-V-S-R-R-R-K-L-L-D-Y-L-K-G-K-D-L-A-R-Y-Q-D-L-I-K-R-L-G-L-R-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-D-I-K-K-D-A-Q-E-R-M-E-K-S-V-E-A-L-K-N-S-L-S-K-V-R-T-G-R-A-H-P-S-L-L-S-G-I-S-V-D-Y-Y-G-A-A-T-P-L-T-Q-V-A-N-V-I-A-E-D-A-R-T-L-A-I-T-V-F-D-K-E-L-T-Q-K-V-E-K-A-I-M-M-S-D-L-G-L-N-P-M-S-A-G-T-V-I-R-V-P-L-P-P-L-T-E-E-R-R-K-D-L-V-K-I-V-R-G-E-A-E-G-G-R-V-A-V-R-N-I-R-R-D-A-N-S-D-L-K-A-L-L-K-E-K-E-I-S-E-D-E-D-R-K-A-Q-D-E-I-Q-K-L-T-D-A-A-V-K-K-I-D-D-V-L-A-A-K-E-K-E-L-M-E-V"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-T-N-T-I-A-Q-I-Q-A-S-I-K-S-I-P-D-Y-P-K-P-G-I-L-F-R-D-V-T-S-L-L-E-D-A-Q-A-Y-Q-A-T-I-Q-L-L-V-D-K-Y-K-D-M-G-F-T-K-V-V-G-T-E-A-R-G-F-L-F-G-A-P-L-A-L-Q-L-G-V-G-F-V-P-V-R-K-P-G-K-L-P-R-N-T-I-A-Q-S-Y-E-L-E-Y-G-V-D-T-L-E-I-H-T-D-A-I-V-E-G-D-K-V-L-V-V-D-D-L-L-A-T-G-G-T-I-E-A-T-T-K-L-I-R-Q-L-G-G-V-V-E-H-A-A-F-V-I-N-L-P-E-I-G-G-D-K-R-L-E-G-L-G-L-N-V-Y-S-I-C-E-F-E-G-H"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-G-G-M-G-N-L-M-K-Q-A-Q-Q-M-Q-E-R-M-Q-K-L-Q-E-E-I-A-N-M-E-V-V-G-E-S-G-A-G-L-V-K-V-T-I-T-G-S-H-S-V-R-R-V-N-I-D-E-S-L-M-E-D-D-K-E-M-L-E-D-L-I-A-A-A-F-N-D-A-A-R-R-V-E-E-T-Q-K-E-K-M-A-A-I-T-G-G-M-Q-L-P-P-G-M-K-M-P-F"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-R-T-S-H-M-L-E-Q-L-M-E-A-L-R-C-L-P-G-V-G-P-K-S-A-Q-R-M-A-F-H-L-L-Q-R-D-R-K-G-G-L-Q-L-A-D-A-L-S-H-A-M-T-E-I-G-H-C-N-E-C-R-T-F-T-E-E-D-V-C-H-I-C-N-N-P-K-R-Q-E-N-G-L-L-C-V-V-E-S-P-A-D-I-A-A-V-E-A-T-G-Q-F-S-G-R-Y-F-V-L-M-G-H-L-S-P-L-D-G-I-G-P-S-D-I-G-L-D-V-L-D-Y-R-L-R-R-G-D-I-K-E-V-I-L-A-T-N-P-T-V-E-G-E-A-T-A-H-Y-I-A-E-L-C-R-E-H-K-V-D-A-S-R-I-A-H-G-V-P-V-G-G-E-L-E-L-V-D-G-T-T-L-S-H-S-L-L-G-R-H-K-L-N"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-K-N-F-E-W-I-T-P-D-S-D-L-L-E-K-E-I-T-Q-I-Q-P-P-K-K-Y-N-V-V-L-N-N-D-D-Y-T-P-M-D-F-V-I-D-V-L-E-R-F-F-S-H-D-L-D-K-A-T-Q-I-M-L-K-V-H-Y-E-G-K-A-I-C-G-T-Y-S-A-E-I-A-E-T-K-V-A-Q-V-T-M-Y-S-R-E-N-E-H-P-L-L-C-T-M-E-Q-A"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-D-V-I-E-M-Q-G-T-V-L-D-T-L-P-N-T-M-F-R-V-E-L-E-N-G-H-V-V-T-A-H-I-S-G-K-M-R-K-N-Y-I-R-I-L-T-G-D-K-V-T-V-E-M-T-P-Y-D-L-S-K-G-R-I-V-F-R-A-R"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-N-L-F-A-S-L-N-Q-F-S-K-N-R-I-S-W-L-L-L-L-L-F-V-V-F-F-E-G-A-A-L-F-F-Q-H-V-M-M-L-S-P-C-V-M-C-I-Y-E-R-V-A-M-L-G-V-G-G-A-A-L-F-G-L-I-A-P-N-N-P-L-V-R-W-L-G-L-A-A-W-G-A-S-A-Y-K-G-L-A-L-S-L-Q-H-V-D-Y-Q-F-N-P-S-P-F-A-T-C-D-L-F-V-T-F-P-D-W-A-P-L-N-Q-W-A-P-W-M-F-E-A-Y-G-D-C-S-K-I-V-W-Q-F-M-T-L-S-M-P-Q-W-L-V-I-I-F-A-G-N-L-V-A-L-A-F-I-V-I-A-Q-F-F-K-S-K"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-D-L-A-E-N-L-F-E-K-L-G-F-S-K-R-D-A-K-D-T-V-E-V-F-F-E-E-I-R-K-A-L-E-N-G-E-Q-V-K-L-S-G-F-G-N-F-D-L-R-D-K-N-E-R-P-G-R-N-P-K-T-G-E-D-I-P-I-T-A-R-R-V-V-T-F-R-P-G-Q-K-L-K-A-R-V-E-N-L-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-Q-A-R-A-R-H-K-K-V-L-K-Q-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-T-K-A-G-Q-Y-A-Y-R-D-R-R-A-K-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-S-R-Q-N-G-L-S-Y-S-R-F-I-N-G-L-K-K-A-S-I-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-A-A-F-A-V-L-V-E-K-A-K-A-A-L"} +{"text": "### FUNCTION Required for spatial organization of the terminus region of the chromosome during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-Q-L-E-N-L-E-C-G-W-K-W-Q-Y-L-I-N-K-W-K-D-G-E-T-I-T-K-Y-I-D-S-S-E-A-D-H-A-V-S-E-L-R-K-L-E-H-E-P-T-K-V-L-E-W-I-D-L-H-M-A-E-E-L-D-K-K-L-K-Q-A-I-R-A-K-R-K-R-H-F-N-A-E-Q-I-H-T-K-K-K-S-I-D-L-D-Y-R-V-W-E-K-L-S-T-R-A-N-E-L-G-C-T-L-S-D-A-I-E-Y-L-L-S-E-A-S-R-S-E-K-A-S-A-A-V-S-T-L-K-E-D-L-S-K-L-L-S-D"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-K-F-E-A-V-V-R-T-E-L-G-K-G-A-S-R-R-L-R-L-A-G-Q-F-P-A-V-V-Y-G-G-E-A-A-P-V-A-V-A-L-N-H-D-D-I-V-N-Q-M-D-K-P-E-F-Y-E-A-I-T-L-V-I-G-G-E-E-V-K-V-K-P-Q-D-V-Q-R-H-A-F-K-P-K-V-E-H-M-D-F-I-R-I"} +{"text": "### FUNCTION Participates in the translocation of lipoproteins from the inner membrane to the outer membrane Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate ### SEQUENCE -M-K-K-W-L-V-V-F-F-L-S-A-S-A-L-A-N-P-Q-Q-E-L-N-Q-R-L-G-M-N-D-G-F-S-A-N-F-N-Q-T-V-T-S-P-E-G-E-V-V-M-E-G-E-G-S-V-D-I-A-R-P-S-L-F-R-W-S-T-S-L-P-D-E-N-L-L-V-S-D-G-K-T-L-W-Y-Y-S-P-F-I-E-Q-V-S-I-Y-W-Q-E-Q-A-V-Q-Q-T-P-F-V-L-L-T-R-N-Q-S-S-D-W-E-N-Y-Q-I-T-Q-D-G-N-V-F-T-L-V-P-K-A-A-D-S-T-Q-G-Q-F-Q-I-D-I-D-A-K-G-I-V-H-G-F-N-V-I-E-Q-D-G-Q-K-G-I-F-K-F-T-D-M-K-L-G-K-P-A-A-A-R-F-T-F-N-I-P-E-G-V-E-V-D-D-Q-R-N"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-R-L-C-A-E-Q-T-H-L-S-A-K-E-I-E-D-A-V-K-D-I-L-E-H-M-A-S-T-L-E-S-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-E-P-R-V-G-R-N-P-K-T-G-D-K-V-E-L-E-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-E-R-V-H-I-G"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-N-L-E-E-R-V-K-K-I-I-V-E-Q-L-G-V-D-E-S-E-V-K-N-E-A-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-A-A-I-D-Y-V-T-A-N-A-Q"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-E-N-Y-Q-L-V-L-A-S-T-S-P-F-R-Q-Q-L-L-E-K-L-A-I-P-F-S-T-L-S-P-N-C-D-E-T-P-L-E-D-E-S-P-Q-Q-L-V-L-R-L-A-E-S-K-A-Q-S-C-Q-I-N-Q-P-S-L-V-I-G-S-D-Q-V-C-V-I-N-G-N-I-V-G-K-P-H-N-R-Q-N-A-I-A-Q-L-T-A-Q-S-G-Q-S-I-V-F-Y-T-G-L-A-V-Y-N-S-E-T-G-E-T-R-S-C-I-D-E-F-K-V-H-F-R-P-L-T-Q-A-Q-I-E-R-Y-V-D-K-E-Q-P-F-Y-C-A-G-S-F-K-S-E-G-L-G-I-A-L-F-E-K-L-E-G-K-D-P-N-T-L-V-G-L-P-L-I-D-L-I-D-L-L-A-Q-Q-G-M-Q-V-L-G"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-Q-I-L-D-F-I-P-L-I-I-F-F-A-L-Y-K-M-Y-D-I-Y-V-A-T-G-A-L-I-A-A-T-A-I-Q-I-V-V-T-Y-A-L-Y-K-K-V-E-K-M-Q-L-I-T-F-L-M-V-A-I-F-G-G-M-T-I-F-L-H-D-D-N-F-I-K-W-K-V-T-I-V-Y-A-V-F-A-I-G-L-T-V-S-H-V-M-G-K-S-A-I-K-G-M-L-G-K-E-I-T-L-P-E-S-V-W-A-N-I-N-W-A-W-V-G-F-F-T-F-C-A-G-L-N-I-Y-V-A-Y-Q-L-P-L-D-V-W-V-N-F-K-V-F-G-L-L-A-A-T-L-V-F-T-V-L-T-G-G-Y-I-Y-K-H-L-P-K-E-Q-N-G-Q-S-S-D-V-P-T-D-E"} +{"text": "### FUNCTION Phosphorelay protein which receives a sensory signal from a sensor kinase and transmit it to LuxO At low cell density, a phosphoryl group is transferred from the sensor kinase, probably on His-56 and this phosphoryl group is further transferred to LuxO ### SEQUENCE -M-E-L-L-N-Q-K-K-I-A-S-L-T-E-E-I-G-A-D-N-V-P-V-L-L-E-I-F-L-S-E-L-E-S-Y-L-K-V-L-C-D-A-T-Y-S-D-K-L-V-Y-L-K-D-I-S-H-A-L-K-S-S-A-A-S-F-G-A-D-A-L-C-H-F-A-V-E-I-D-T-R-A-K-E-G-D-A-L-D-E-T-Q-D-V-V-A-M-I-D-R-L-H-Q-T-Q-Q-A-Y-L-S-W-Q-A-N-G-F"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-T-E-Y-I-L-L-L-I-G-T-V-L-V-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-L-E-T-A-I-G-M-G-L-A-T-T-F-V-L-T-M-A-S-V-C-A-Y-L-V-E-S-Y-I-L-E-P-L-H-I-E-Y-L-R-T-M-S-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-V-V-H-K-T-S-P-T-L-Y-R-L-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-I-N-E-N-H-S-F-V-E-S-I-I-Y-G-F-G-A-A-V-G-F-S-L-V-L-I-L-F-A-S-M-R-E-R-I-S-A-A-D-V-P-A-P-F-K-G-A-S-I-A-M-I-T-A-G-L-M-S-L-A-F-M-G-F-T-G-L-V-K"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-L-E-F-F-R-P-Q-K-K-T-S-A-S-L-A-K-E-R-L-Q-I-I-V-A-E-R-R-S-Q-N-D-P-A-P-S-Y-L-P-Q-L-K-E-D-I-L-K-V-I-S-K-Y-V-A-I-D-P-A-M-V-D-L-T-F-E-H-K-D-D-D-I-S-V-L-E-L-N-V-K-L-P-D-E-E-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-Q-Q-I-K-L-L-V-G-L-A-N-P-G-P-E-Y-A-K-T-R-H-N-A-G-A-W-V-V-E-E-L-A-R-V-H-N-I-T-L-K-N-E-A-K-F-Y-G-L-T-G-R-I-V-M-N-G-Q-E-L-R-L-L-I-P-T-T-F-M-N-L-S-G-K-A-I-A-A-L-A-K-F-Y-Q-I-Q-P-E-E-I-M-V-A-H-D-E-L-D-L-P-P-G-I-A-K-F-K-K-G-G-G-H-G-G-H-N-G-L-R-D-T-I-S-K-L-G-N-N-K-E-F-Y-R-L-R-I-G-I-G-H-P-G-H-K-D-K-V-A-G-F-V-L-G-K-A-P-A-S-E-Q-S-L-L-D-A-T-V-D-E-S-V-R-C-L-D-I-L-I-K-D-G-L-S-K-A-Q-N-R-L-H-T-F-K-A-E"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-I-E-L-D-L-Q-L-A-V-E-D-Q-N-G-L-P-S-A-Q-D-F-Q-T-W-L-D-K-T-I-P-P-F-Q-P-Q-A-E-V-T-I-R-I-V-D-S-Q-E-S-H-Q-L-N-H-D-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-A-P-P-G-M-E-M-D-L-L-G-D-L-V-I-C-R-Q-V-V-E-Q-E-A-I-E-Q-D-K-P-L-M-A-H-W-A-H-M-V-V-H-G-S-L-H-L-L-G-Y-D-H-I-E-D-D-E-A-E-E-M-E-S-L-E-T-E-I-M-Q-G-M-G-F-T-D-P-Y-L-A-E-K-E"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-Q-L-I-A-V-G-T-K-M-P-K-W-V-E-E-G-F-Q-E-Y-R-R-R-F-P-H-D-M-P-L-E-L-I-E-I-T-A-G-K-R-G-K-N-A-D-I-A-R-I-L-Q-K-E-G-E-A-M-L-A-A-I-P-K-G-N-R-I-V-T-L-D-I-P-G-K-K-W-D-T-P-E-L-A-Q-Q-L-E-A-W-K-L-D-G-R-D-V-S-I-L-I-G-G-P-E-G-L-A-P-A-C-K-A-A-A-E-Q-S-W-S-L-S-A-L-T-L-P-H-P-L-V-R-I-V-M-A-E-S-L-Y-R-A-W-S-I-T-T-N-H-P-Y-H-R-E"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-T-K-K-P-E-N-M-S-F-E-A-T-I-E-E-L-D-N-L-V-D-Q-L-E-N-G-D-L-A-L-D-D-A-L-K-K-F-E-R-G-I-A-L-A-R-A-S-Q-A-K-L-T-E-A-E-Q-R-V-S-I-L-L-S-D-S-D-D-A-P-L-S-D-F-S-T-L-A-E"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-G-A-S-V-K-P-A-A-R-R-N-A-R-Q-F-A-L-Q-A-I-Y-S-W-Q-I-T-K-E-N-V-A-T-I-E-A-Q-F-L-A-G-E-K-Y-D-E-E-E-H-R-A-A-E-P-A-L-A-A-P-E-T-D-V-A-Y-F-R-D-L-L-T-G-V-V-L-S-H-T-E-L-D-S-K-I-R-P-Y-V-S-R-P-M-Q-D-L-D-M-M-E-L-A-L-L-R-L-A-M-Y-E-M-T-R-R-E-D-V-P-Y-K-V-V-I-N-E-A-I-E-L-A-K-V-F-A-A-E-D-S-H-K-F-V-N-G-V-L-D-K-A-A-P-H-V-R-K-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-S-E-N-D-T-K-V-I-D-S-R-L-V-A-D-G-H-Q-V-R-R-R-R-Q-C-L-A-C-N-E-R-F-T-T-F-E-T-A-E-L-L-M-P-K-V-I-K-S-N-G-N-R-E-P-F-N-E-D-K-M-V-G-G-I-Q-R-A-L-E-K-R-P-V-S-A-D-A-I-E-L-A-I-S-M-I-K-S-K-L-R-A-T-G-E-R-E-V-P-S-K-M-I-G-N-L-V-M-E-Q-L-K-H-L-D-K-V-A-Y-I-R-F-A-S-V-Y-R-S-F-E-D-I-R-E-F-G-E-E-I-A-R-L-E-D"} +{"text": "### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-S-E-V-T-N-N-P-T-H-N-R-L-L-A-K-L-R-A-M-G-P-Y-L-R-D-P-Q-S-K-E-G-L-Y-Y-F-D-C-L-S-V-C-I-D-D-R-K-S-P-E-L-R-E-F-W-G-W-W-M-E-L-E-A-T-E-G-G-F-T-A-N-Y-H-I-G-K-Y-D-V-E-G-N-W-L-D-L-A-I-P-K-N-A-L-E-E-V-N-K-T-Q-N-C-F-H-L-K-L-V-K-T-L-E-E-N-F-Q-L-S-V-A-Y-H-E-Q-S-V-E-F-V"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-N-E-E-N-K-I-N-E-E-A-L-K-Q-Q-D-A-A-E-V-E-V-E-A-V-G-T-D-A-D-I-E-W-N-E-E-A-D-E-S-A-V-K-I-A-E-L-E-A-A-L-L-A-S-E-A-R-V-K-E-Q-Q-D-S-V-L-R-A-K-A-E-V-E-N-M-R-R-R-T-E-Q-E-I-D-K-A-R-K-Y-A-L-N-R-F-A-E-E-L-L-P-V-I-D-N-L-E-R-A-I-Q-A-A-D-A-E-S-E-A-V-K-P-L-L-E-G-V-E-L-T-H-K-T-F-V-D-V-V-S-K-F-G-L-K-E-I-N-P-E-G-Q-P-F-N-P-E-W-H-Q-A-M-S-I-Q-E-S-P-D-H-E-S-N-T-V-M-F-V-M-Q-K-G-Y-E-L-N-G-R-V-I-R-P-A-M-V-M-V-A-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-N-S-K-P-K-A-G-S-N-T-I-A-L-N-K-K-A-R-H-E-Y-F-I-E-D-E-I-E-A-G-M-E-L-Q-G-W-E-V-K-A-L-R-Q-G-K-A-N-I-S-E-S-Y-V-F-M-R-D-G-E-A-F-V-S-G-M-T-I-T-P-L-N-Q-A-S-T-H-V-V-A-N-P-T-R-V-R-K-L-L-M-S-R-R-E-L-D-N-L-L-G-R-I-N-R-E-G-M-T-L-A-A-L-S-L-Y-W-A-R-S-W-V-K-I-K-I-G-V-A-K-G-K-K-L-H-D-K-R-D-D-I-K-D-R-D-W-Q-R-Q-K-A-R-V-M-K-S-S-L-R"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-H-F-E-L-F-G-L-P-P-Q-F-S-L-D-G-S-L-L-S-S-Q-F-R-E-L-Q-K-R-F-H-P-D-N-F-A-T-A-S-E-R-D-R-L-L-A-V-Q-K-A-A-Q-I-N-D-A-Y-Q-V-L-K-N-P-I-S-R-A-E-Y-L-L-S-Q-N-G-L-E-I-R-G-E-Q-Q-T-M-Q-D-P-M-F-L-M-E-Q-M-E-L-R-E-E-L-E-E-I-P-H-G-S-D-A-E-S-A-L-A-A-F-D-A-R-V-S-K-M-Y-K-Q-H-L-A-S-I-E-Q-E-L-N-D-A-Q-W-P-Q-A-A-D-R-V-R-K-L-K-F-I-A-K-L-K-N-E-I-E-L-V-E-E-K-L-F-G"} +{"text": "### FUNCTION Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins ### SEQUENCE -M-K-L-T-S-K-G-R-Y-A-V-T-A-M-L-D-V-A-L-H-S-Q-K-S-P-V-P-L-A-D-I-S-E-R-Q-G-I-S-L-S-Y-L-E-Q-L-F-S-K-L-R-K-A-G-L-V-A-S-V-R-G-P-G-G-G-Y-R-L-G-A-D-A-F-T-I-S-I-G-T-V-I-A-A-V-D-E-S-V-D-A-T-K-C-Q-G-K-G-D-C-Q-G-G-T-R-C-L-T-H-T-L-W-R-D-L-S-S-R-I-T-D-F-L-N-N-I-T-L-G-E-L-M-S-D-N-E-V-I-E-I-S-D-R-Q-D-I-D-L-A-V-N-H-G-L-A-N-K-T-I-N-T-A-P-I-G-V-N-F-R-S"} +{"text": "### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-S-Q-Q-P-E-Y-T-D-W-Q-Q-I-V-D-L-V-K-H-S-V-E-Q-K-Q-H-D-M-L-L-T-M-L-M-T-P-D-E-R-E-A-L-V-S-R-V-N-I-V-R-E-L-L-K-G-E-L-S-Q-R-Q-I-S-Q-M-L-G-V-G-I-A-T-I-T-R-G-S-N-E-L-K-L-K-S-D-E-D-K-A-R-L-N-Q-L-L-E-G-T-K-K-G-G"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-N-K-S-A-K-K-R-A-I-Q-A-E-K-R-R-Q-H-N-A-S-R-R-S-M-M-R-T-Y-M-K-K-T-V-A-A-I-A-A-G-D-K-E-A-A-T-A-A-F-A-V-V-T-P-I-L-D-R-M-A-T-K-G-L-I-H-K-N-K-A-A-R-H-K-S-R-F-A-A-Q-I-K-A-L"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-G-D-G-Y-R-L-N-V-G-I-V-I-C-N-N-H-G-Q-V-F-W-A-K-R-Y-G-Q-H-S-W-Q-F-P-Q-G-G-I-D-D-G-E-T-P-E-Q-A-M-F-R-E-L-Y-E-E-V-G-L-T-H-K-D-V-K-I-I-A-S-S-R-H-W-L-R-Y-K-L-P-K-R-L-V-R-W-D-S-K-P-V-C-I-G-Q-K-Q-K-W-F-L-L-R-L-E-C-D-E-S-K-I-N-M-Q-K-G-S-S-P-E-F-D-G-W-R-W-V-S-Y-W-Y-P-V-R-Q-V-V-S-F-K-R-D-V-Y-R-R-A-M-K-E-F-A-S-L-A-M-P-F-R-E-R-K-L-K-G-K-K-V-K-R-R-G"} +{"text": "### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-Q-G-I-Q-I-T-K-A-A-N-D-D-L-L-N-S-I-W-L-L-D-S-E-K-N-E-A-R-C-V-A-A-V-S-G-Y-E-A-D-Q-I-V-A-I-N-E-L-G-E-F-E-S-R-E-V-A-I-E-A-A-P-R-I-E-G-G-Q-H-L-N-V-N-V-L-K-R-E-T-L-E-D-A-V-A-H-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-A-R-T-F-T-E-S-L"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-V-A-K-P-E-T-V-K-R-D-W-Y-V-V-D-A-E-G-K-T-L-G-R-L-A-S-E-I-A-S-R-L-R-G-K-H-K-A-E-Y-T-P-H-V-D-T-G-D-Y-I-I-V-I-N-A-E-K-V-T-V-T-G-N-K-A-A-A-K-T-Y-Y-R-H-T-E-F-P-G-G-I-K-S-I-T-F-D-K-L-I-V-R-K-P-E-M-V-I-E-L-A-V-K-G-M-L-P-R-G-P-L-G-R-A-M-Y-R-K-L-K-V-Y-A-G-A-E-H-N-H-V-A-Q-Q-P-K-V-L-D-I"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-S-E-G-Q-T-L-R-L-E-K-L-D-V-E-T-G-A-T-V-E-F-D-K-V-L-L-V-A-N-G-E-D-I-K-V-G-A-P-L-V-E-G-G-K-V-V-A-E-V-V-Q-H-G-R-G-D-K-V-K-I-V-K-F-R-R-R-K-H-S-R-K-Q-Q-G-H-R-Q-W-F-T-E-V-K-I-T-G-I-N-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-R-P-S-E-K-Q-D-N-L-V-R-A-F-K-A-L-L-K-E-E-R-F-G-S-Q-G-E-I-V-E-A-L-K-Q-E-G-F-E-N-I-N-Q-S-K-V-S-R-M-L-T-K-F-G-A-V-R-T-R-N-A-K-M-E-M-V-Y-C-L-P-T-E-L-G-V-P-T-V-S-S-S-L-R-E-L-V-L-D-V-D-H-N-Q-A-L-V-V-I-H-T-G-P-G-A-A-Q-L-I-A-R-M-L-D-S-L-G-K-S-E-G-I-L-G-V-V-A-G-D-D-T-I-F-I-T-P-T-L-T-I-T-T-E-Q-L-F-K-S-V-C-E-L-F-E-Y-A-G"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-Q-P-T-R-A-R-K-R-V-R-K-Q-V-A-D-G-V-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-A-W-A-T-A-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-R-C-A-E-M-A-K-E-Y-G-L-K-N-L-E-V-M-V-K-G-P-G-P-G-R-E-S-T-V-R-A-L-N-A-A-G-F-R-I-T-N-I-V-D-A-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-A-V-I-A-L-T-A-I-Y-G-I-G-K-T-R-S-K-A-I-L-A-D-V-G-I-A-E-D-V-K-I-S-E-L-T-E-E-Q-I-D-Q-L-R-D-G-V-A-K-Y-T-V-E-G-D-L-R-R-E-V-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-S-L-P-L-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-S-P-A-A-G-S-K-H-A-P-K-R-V-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-K-S-R-S-G-G-K-V-R-P-G-F-E-G-G-Q-M-P-L-K-Q-R-L-P-K-F-G-F-T-S-R-K-S-L-V-S-A-E-V-R-V-A-E-L-A-K-V-T-G-D-V-V-D-L-N-S-L-K-A-A-N-V-I-T-K-N-I-E-N-V-K-I-V-L-S-G-E-I-N-K-A-V-T-V-K-G-L-R-V-T-K-G-A-K-A-A-I-E-A-A-G-G-K-I-E-E"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-K-E-Q-Q-V-Q-A-N-D-L-Q-E-K-L-I-A-V-N-R-V-S-K-T-V-K-G-G-R-I-M-S-F-T-A-L-T-V-V-G-D-G-N-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-N-M-V-T-I-A-L-N-E-G-T-L-H-H-P-V-K-G-R-H-S-G-S-K-V-Y-M-Q-P-A-A-E-G-T-G-V-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-H-N-V-L-S-K-A-Y-G-S-T-N-P-I-N-I-V-R-A-T-I-D-A-L-V-D-V-K-S-P-E-M-V-A-A-K-R-G-L-T-V-E-A-I-S-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-A-S-R-I-R-R-A-T-R-A-R-R-K-I-A-E-L-G-A-T-R-L-V-V-H-R-T-P-R-H-V-Y-A-Q-V-I-A-A-N-G-S-E-V-I-A-A-A-S-T-V-E-K-A-I-R-E-Q-V-K-Y-T-G-N-I-E-A-A-K-A-V-G-K-A-V-A-E-R-A-L-E-K-G-V-S-T-V-A-F-D-R-S-G-F-Q-Y-H-G-R-V-A-A-L-A-D-S-A-R-E-A-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-A-I-P-A-G-V-E-V-K-L-N-G-Q-E-I-T-V-K-G-A-K-G-E-L-S-R-V-I-N-N-A-V-V-I-A-Q-E-E-N-K-L-T-F-G-P-R-E-G-V-A-N-A-W-A-Q-A-G-T-A-R-A-L-V-N-N-M-V-V-G-V-T-E-G-F-T-R-K-L-I-L-K-G-V-G-Y-R-A-A-I-K-G-N-A-V-G-L-T-L-G-F-S-H-P-V-E-H-E-L-P-A-G-I-K-A-E-C-P-S-Q-T-E-I-V-L-T-G-C-D-K-Q-L-I-G-Q-V-A-A-D-I-R-A-Y-R-A-P-E-P-Y-K-G-K-G-I-R-Y-A-D-E-N-V-R-S-K-E-A-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-S-D-M-L-T-R-I-R-N-G-Q-A-A-N-K-V-A-V-K-M-P-S-S-K-L-K-V-A-I-A-A-L-L-K-A-E-G-Y-I-V-D-F-A-V-E-G-E-A-K-P-E-L-E-V-T-L-K-Y-F-Q-A-K-P-V-I-E-Q-L-K-R-V-S-R-P-G-L-R-V-Y-K-K-K-D-D-L-P-S-V-M-G-G-L-G-V-A-V-V-S-T-S-K-G-L-M-S-D-R-A-A-R-K-A-G-L-G-G-E-I-I-C-Y-V-A"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-E-A-K-R-A-K-L-V-A-K-F-A-E-K-R-A-S-L-K-A-I-I-S-D-V-N-V-S-E-E-D-R-W-N-A-V-L-K-L-Q-T-L-P-R-D-S-S-A-S-R-Q-R-N-R-C-N-Q-T-G-R-P-H-G-Y-L-R-K-F-G-L-S-R-I-K-V-R-E-A-C-M-K-G-E-I-P-G-L-R-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-K-S-S-V-V-A-E-L-T-K-Q-F-G-Y-T-S-V-M-Q-V-P-R-I-E-K-I-T-L-N-M-G-V-G-D-A-I-N-D-K-K-L-L-E-N-A-A-A-D-M-A-T-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-V-A-G-F-K-I-R-E-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-D-F-M-E-R-L-I-S-I-A-L-P-R-V-R-D-F-R-G-V-N-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-F-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-S-A-G-T-D-E-E-G-R-A-L-L-A-A-F-N-F-P-F-R-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-N-D-E-V-I-V-L-A-G-K-D-K-G-K-K-G-K-V-T-K-V-L-A-T-G-K-V-I-V-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-L-G-I-Q-G-G-I-V-E-Q-E-A-A-I-D-V-S-N-V-A-I-F-N-A-A-T-G-K-A-D-R-I-G-F-R-F-E-D-G-Q-K-V-R-F-F-K-S-N-G-E-T-V-S-N"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-M-L-D-A-A-D-N-S-G-A-R-S-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-H-I-G-D-V-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-D-V-L-K-A-V-V-V-R-T-R-K-G-V-R-R-P-D-G-S-V-I-R-F-D-R-N-A-C-V-L-L-N-N-N-T-E-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-G-D-K-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-D-K-I-R-T-Q-L-G-R-V-V-S-D-K-M-D-K-S-I-V-V-A-I-E-R-M-V-K-H-P-I-Y-G-K-F-V-K-R-T-T-K-V-H-A-H-D-E-N-N-E-C-G-I-G-D-T-V-E-I-R-E-C-R-P-L-S-K-T-K-S-W-T-L-V-K-V-V-E-K-A-K-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-V-H-T-G-R-N-R-G-L-A-K-G-T-E-V-S-F-G-S-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-H-I-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-E-V-R-Q-G-K-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-K-V-M-Y-E-V-D-G-V-P-E-E-L-A-R-E-A-F-R-L-A-A-R-K-L-P-F-K-T-T-F-V-T-K-Q-V-M"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-I-A-K-H-N-F-A-R-I-S-P-Q-K-A-R-L-V-A-D-L-I-R-G-K-S-V-D-Q-A-L-E-I-L-T-F-S-N-K-K-A-A-V-L-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-E-G-A-D-I-D-D-L-N-V-A-K-I-F-V-D-E-G-P-T-M-K-R-I-M-P-R-A-K-G-R-A-D-R-I-L-K-R-S-S-H-I-T-V-V-V-A-D-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-V-E-K-A-V-E-S-G-D-K-K-P-L-K-T-W-S-R-R-S-M-I-I-P-T-M-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-F-V-T-E-E-M-I-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-A-A-D-K-K-A-K-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-T-Q-E-R-L-L-K-V-L-R-A-P-H-I-S-E-K-A-T-M-A-A-E-K-A-N-T-I-V-F-K-V-A-K-D-A-T-K-K-E-I-K-A-A-V-E-Q-L-F-E-V-E-V-K-S-V-N-T-L-I-T-K-G-K-T-K-R-Q-G-L-R-Q-G-R-R-S-D-V-K-K-A-Y-V-T-L-K-E-G-Q-D-L-D-F-V-G-G-A-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA It is important during the early stages of 50S assembly It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-E-L-M-V-K-G-A-A-A-L-T-V-S-E-A-T-F-G-R-E-F-N-E-A-L-V-H-Q-V-V-V-A-Y-A-A-G-A-R-Q-G-T-R-A-Q-K-T-R-S-E-V-S-G-G-G-A-K-P-W-R-Q-K-G-T-G-R-A-R-A-G-T-I-R-S-P-L-W-R-T-G-G-V-T-F-A-A-K-P-Q-D-H-S-Q-K-V-N-K-K-M-Y-R-G-A-M-K-S-I-L-S-E-L-V-R-Q-E-R-L-I-V-V-D-N-F-S-V-E-A-P-K-T-K-E-L-V-A-K-L-K-E-L-E-L-N-D-V-L-I-V-T-G-E-V-D-E-N-L-F-L-A-A-R-N-L-Y-K-V-D-A-R-D-V-A-G-I-D-P-V-S-L-I-A-F-N-K-V-L-M-T-A-D-A-V-K-Q-V-E-E-M-L-A"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-R-I-R-I-R-L-K-A-F-D-Y-K-L-I-D-A-S-T-A-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-R-F-T-V-L-I-S-P-H-V-N-K-K-A-R-D-Q-Y-E-I-R-T-H-K-R-L-I-D-I-V-E-P-T-D-K-T-V-D-A-L-M-R-L-D-L-A-A-G-V-D-V-Q-I-S-L-G"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-D-A-V-E-K-V-G-N-R-F-D-L-V-L-I-A-A-R-R-A-R-Q-M-Q-T-G-G-K-D-S-L-V-P-E-E-N-D-K-P-T-V-I-A-L-R-E-I-E-E-G-L-I-T-K-E-V-L-D-A-R-E-R-Q-E-Q-Q-E-Q-E-A-A-E-L-A-A-V-S-S-I-A-R-N-R"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-K-T-K-M-I-T-R-E-G-Y-N-K-L-K-Q-E-L-D-Y-L-W-K-E-H-R-P-E-I-T-Q-K-V-S-W-A-A-S-L-G-D-R-S-E-N-A-D-Y-T-Y-N-K-R-L-L-R-Q-I-D-R-R-V-R-F-L-S-K-F-L-P-E-V-K-I-V-D-Y-A-P-Q-Q-E-G-K-V-F-F-G-A-W-V-E-I-E-N-E-A-G-E-V-M-K-F-R-I-V-G-P-E-E-I-Y-G-D-A-K-G-Y-I-S-I-D-S-P-M-A-R-A-L-L-K-K-E-V-D-D-E-V-Q-V-P-T-P-S-G-I-K-E-W-F-I-N-S-I-E-Y-D-K-G-Q"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-S-N-I-T-I-T-E-A-A-Q-T-H-F-A-N-L-L-G-Q-Q-P-D-G-T-N-I-R-V-F-V-V-N-P-G-T-Q-N-A-E-C-G-V-S-Y-C-P-P-E-A-V-E-A-T-D-T-E-I-P-Y-Q-S-F-S-A-Y-V-D-E-L-S-L-P-F-L-E-D-A-E-I-D-Y-V-T-D-K-M-G-S-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-A-D-D-A-P-L-L-E-R-V-E-Y-A-I-Q-T-Q-V-N-P-Q-L-A-G-H-G-G-H-V-K-L-M-E-I-T-D-A-G-V-A-I-V-A-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-E-G-I-E-K-E-L-L-Q-Q-F-S-G-E-L-T-A-V-R-D-A-T-E-H-D-R-G-D-H-S-Y-Y"} +{"text": "### FUNCTION A GTPase-activating protein that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-S-R-K-K-K-S-R-K-P-G-A-A-G-A-P-E-F-M-V-T-R-N-R-S-E-S-D-V-A-G-R-L-R-K-K-D-K-K-R-K-G-L-K-A-G-G-R-N-S-E-E-G-A-Q-Q-K-H-G-S-S-Q-V-R-D-P-R-L-G-S-K-K-K-I-P-L-I-V-E-P-A-K-K-L-T-K-Q-E-R-R-L-S-A-E-Q-E-L-E-M-L-E-N-D-A-K-L-N-V-L-L-D-R-I-E-S-G-E-N-L-G-R-G-L-Q-Q-Y-V-D-E-K-L-D-R-I-E-Q-L-M-S-Q-L-G-L-L-E-P-E-A-E-E-E-F-E-D-E-A-P-V-R-K-S-R-S-D-D-D-L-L-A-D-F-E-D-F-D-M-D-D-Y-K-G"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-W-E-L-V-L-I-F-V-V-G-L-V-V-L-G-P-E-R-L-P-H-A-I-R-S-V-A-R-F-V-S-A-A-K-S-M-A-N-S-V-K-D-E-L-A-H-E-L-K-V-Q-E-L-Q-E-N-L-R-K-A-E-Q-M-G-M-E-E-L-S-P-D-L-K-A-S-V-E-Q-L-K-Q-A-A-Q-S-V-N-R-P-Y-A-D-V-S-A-K-N-E-A-T-S-S-S-S-S-D-A-T-H-Q-T-E-A-T-K-T-S-A-A-N-T-K-S-E"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-I-S-I-W-Q-L-L-I-I-A-V-I-V-V-L-L-F-G-T-K-K-L-R-G-I-G-S-D-L-G-G-A-I-K-G-F-K-K-A-M-N-E-E-E-S-E-K-K-D-A-D-F-E-P-K-S-L-E-Q-Q-N-K-Q-A-A-T-E-S-K-K-D-K-E-Q-A"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-N-Q-P-N-S-L-Y-L-A-L-L-I-E-A-K-W-Q-N-P-E-D-F-H-F-S-S-D-F-A-K-H-W-L-L-E-Q-G-S-L-S-R-R-L-A-R-H-C-Q-H-L-T-V-E-L-M-R-N-E-K-S-G-V-G-Q-L-T-M-Q-E-T-Q-G-L-S-P-E-I-C-L-I-R-E-V-V-L-S-G-D-Q-T-P-W-V-L-G-R-T-L-I-P-E-T-T-L-A-D-Q-P-Y-D-L-A-T-L-G-D-I-P-L-G-L-T-V-F-S-A-E-Q-V-E-R-D-A-L-Q-V-A-W-I-E-T-P-Q-G-R-L-L-A-R-R-S-R-L-W-M-N-H-K-P-M-L-V-A-E-L-F-L-P-D-A-P-I-Y-S-R-E-S-V"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-E-Q-F-K-H-I-D-V-Q-G-A-H-A-L-I-S-R-G-E-A-R-L-V-D-I-R-D-P-Q-S-F-A-V-A-H-A-Q-S-A-F-H-L-T-N-D-S-I-V-N-F-M-Q-Q-V-E-F-E-Q-P-V-L-V-M-C-Y-H-G-I-S-S-Q-G-A-A-Q-Y-L-V-N-Q-G-F-E-E-V-Y-S-V-D-G-G-F-E-A-W-H-R-A-S-L-P-V-E-A-S"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-N-T-E-F-H-Q-L-V-D-N-E-L-Q-L-I-E-E-A-I-D-E-S-G-A-D-I-D-Y-E-T-T-G-N-V-M-T-L-E-F-D-D-R-S-Q-I-I-I-N-R-Q-E-P-M-Q-E-I-W-L-A-S-K-S-G-G-F-H-F-Q-Y-K-A-G-Q-W-I-C-S-K-T-G-V-E-F-A-H-M-V-K-Q-E-C-E-K-H-A-G-E-S-I-D-W-A"} +{"text": "### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-S-F-N-P-E-L-A-T-K-T-L-E-A-E-G-L-R-C-P-E-P-V-M-M-V-R-K-T-I-R-T-M-Q-D-G-E-V-L-L-V-K-A-D-D-P-S-T-T-R-D-I-P-S-F-C-R-F-M-D-H-Q-L-I-A-A-Q-T-D-E-L-P-Y-Q-Y-L-I-K-K-G-L"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-T-Y-A-F-N-R-E-L-R-L-L-T-P-E-H-Y-Q-N-V-F-Q-Q-A-H-R-A-G-S-P-H-F-T-I-I-A-R-N-N-N-L-S-H-P-R-L-G-L-A-V-P-K-K-Q-I-K-T-A-V-G-R-N-R-F-K-R-L-A-R-E-S-F-R-N-T-Q-H-Q-L-P-N-K-D-F-V-V-I-A-K-K-S-A-Q-D-L-S-N-E-E-L-F-K-L-F-D-K-L-W-H-R-L-S-R-P-S-R-G"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-K-V-D-H-T-K-M-P-A-P-A-V-R-L-A-K-T-M-T-T-P-K-G-D-E-I-A-V-F-D-L-R-F-C-R-P-N-Q-E-I-L-S-E-K-G-I-H-T-L-E-H-L-F-A-G-F-M-R-E-H-L-N-G-E-G-I-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-V-P-K-N-A-R-V-L-E-A-W-R-R-S-M-E-D-I-L-T-L-K-S-E-E-E-I-P-E-L-N-I-Y-Q-C-G-T-A-C-M-H-S-L-K-E-A-Q-E-I-A-R-T-V-L-D-R-G-I-S-I-M-D-N-E-A-L-K-L-Q-L"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-I-G-H-S-T-Q-E-K-I-E-K-L-V-Q-S-C-G-C-N-L-Y-D-L-L-L-L-K-E-N-E-R-S-I-L-R-L-Y-I-T-K-E-V-G-V-S-L-D-D-C-A-M-V-S-D-L-I-S-P-L-L-D-V-E-D-P-L-A-G-E-Y-F-L-E-V-S-S-P-G-I-E-R-P-L-K-R-P-A-H-Y-Q-H-A-L-G-E-L-A-R-I-K-F-A-D-K-N-E-I-E-G-E-I-E-A-A-D-E-T-S-V-K-L-K-G-E-E-P-I-P-Y-S-L-I-K-K-A-Q-T-F-Y-R-W"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-E-K-S-V-K-L-Q-R-T-E-S-L-L-K-E-V-I-P-E-A-L-S-T-L-S-D-T-R-L-N-S-L-G-V-V-E-V-D-C-S-K-G-K-Y-H-A-E-V-Y-L-D-A-P-F-A-T-P-E-E-K-R-E-I-L-R-Q-L-R-L-A-E-G-T-I-R-D-H-C-L-S-A-T-G-W-F-K-C-P-R-F-H-F-N-F-D-D-S-T-D-K-A-N-R-L-D-A-I-F-E-Q-L-K-K-E-R-E-S"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-E-F-E-V-K-S-P-I-L-G-F-E-S-V-R-G-M-R-L-E-K-I-D-D-L-F-M-K-L-K-N-A-E-A-D-S-P-V-F-T-L-V-N-P-F-L-L-R-E-Y-D-F-E-I-P-L-A-M-K-V-L-L-D-L-K-E-N-T-N-L-L-V-L-N-I-M-I-I-H-T-P-L-E-S-S-T-V-N-F-L-A-P-V-I-F-N-F-D-N-H-T-M-G-Q-L-V-L-E-S-H-R-Y-P-A-Y-G-L-A-E-T-I-S-S-F-F-N-S-D-S-T-P-T-Q-E-A"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-F-L-D-K-F-F-G-K-E-K-S-S-A-K-S-A-S-D-R-L-K-L-V-L-A-H-E-R-A-V-N-L-P-Y-L-E-E-M-K-R-E-I-L-E-V-I-K-K-Y-T-H-A-E-K-I-E-I-K-A-D-S-N-Q-Q-I-D-T-L-E-V-E-I-V-L-G-K-N-S"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-T-M-F-I-V-K-P-T-L-T-P-E-E-I-V-E-K-I-N-F-Y-K-E-A-I-I-K-N-G-G-E-I-C-A-T-Q-D-M-G-M-R-N-L-A-Y-E-I-N-K-N-K-R-G-Y-Y-F-V-V-Y-F-K-S-A-P-S-L-V-I-E-L-E-R-L-Y-R-I-N-E-D-I-L-R-F-I-V-I-K-Y-E-S-K-K-E-Q-N-A-W-N-T-M-V-D-K-V-N-K-K-A-E-A-P-K-S-A-P-V-A-A-P-E-T-A-P-V-A-P-E-A-T-P-E-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-E-K-K-R-Y-S-K-R-Y-C-K-Y-T-E-A-K-I-E-F-I-D-Y-K-D-V-E-M-L-K-H-S-L-S-E-R-Y-K-I-M-P-R-R-L-T-G-N-S-K-R-W-Q-E-R-V-E-V-A-I-K-R-A-R-H-M-A-L-I-P-Y-I-I-D-R-K-K-V-V-E-N-P-F-K-I"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-V-Y-E-L-K-S-P-L-L-G-F-E-E-I-K-E-F-D-L-V-E-V-D-E-M-F-A-K-I-K-A-I-N-N-P-S-I-E-I-T-L-A-N-P-Y-A-L-R-E-Y-S-F-D-I-P-A-Y-I-Q-A-L-L-D-I-N-A-Q-S-K-V-R-V-F-C-T-V-V-I-Q-N-P-I-D-E-S-R-V-N-F-L-A-P-L-I-F-N-D-D-N-Q-T-A-A-Q-I-A-L-S-I-K-D-Y-P-D-F-S-V-A-D-K-I-K-N-Y-V-K-E"} +{"text": "### FUNCTION Participates in the translocation of lipoproteins from the inner membrane to the outer membrane Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate ### SEQUENCE -M-R-I-A-L-L-W-V-A-F-G-A-L-A-L-A-A-F-E-S-I-G-S-F-R-S-E-F-V-Q-T-I-R-S-E-D-G-K-I-I-E-Y-R-G-R-V-Y-A-K-S-P-Y-Y-G-L-W-K-Y-E-K-P-M-E-K-E-I-Y-I-V-D-K-Q-V-V-I-Y-E-P-A-L-E-Q-A-T-V-S-S-L-Q-N-S-I-D-F-M-A-L-L-R-Q-S-K-R-N-S-E-G-I-Y-E-A-T-V-F-E-Q-K-Y-Q-I-L-A-D-E-K-G-E-P-Q-K-V-F-F-I-D-K-L-H-N-E-V-Q-I-I-F-K-N-A-E-I-N-P-V-L-E-K-E-M-F-L-F-M-P-S-G-E-I-D-L-I-R-Q"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Q-T-L-L-A-I-F-V-G-A-G-F-G-A-L-L-R-W-F-L-G-L-K-L-N-A-L-A-P-L-I-P-L-G-T-L-G-A-N-W-L-G-G-Y-L-I-G-L-A-L-A-F-F-S-T-H-P-L-L-S-P-E-W-R-L-L-I-I-T-G-F-L-G-G-L-T-T-F-S-T-F-S-A-E-M-V-S-L-L-Q-W-G-R-Y-G-A-L-A-L-G-V-A-L-H-V-G-G-S-I-G-M-T-L-L-G-I-F-T-F-S-F-I-Q-R-I-G-G"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-I-E-L-L-L-L-S-L-A-L-S-M-D-A-F-A-V-S-L-G-L-G-A-R-F-G-Y-N-K-R-E-S-L-R-P-A-L-S-F-G-I-F-Q-G-I-M-P-L-L-G-F-F-V-G-V-T-F-I-A-F-I-S-A-F-D-H-Y-L-A-F-G-I-L-A-L-I-G-A-K-M-I-Y-E-G-L-S-Q-S-E-E-E-R-L-D-E-L-S-H-R-T-L-L-I-L-S-I-A-T-S-I-D-A-L-A-A-G-V-S-L-H-L-I-D-V-N-V-F-L-S-C-T-I-I-A-F-T-T-F-L-L-S-Y-L-G-V-L-W-G-K-R-A-G-E-Q-C-K-R-G-A-E-I-L-G-G-V-I-L-I-G-I-G-S-K-I-L-L-E-H-L-F-F"} +{"text": "### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-I-L-S-R-K-E-E-E-S-I-V-I-G-D-E-I-V-I-K-V-V-S-I-D-K-G-S-V-K-L-G-F-E-A-P-P-H-M-L-I-L-R-E-E-L-K-K-A-V-A-D-E-N-L-K-A-S-A-Q-S-D-E-I-A-L-T-S-L-S-Q-K-L-K-K"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-K-T-K-E-E-V-V-G-T-P-R-E-I-F-A-P-N-G-H-W-I-S-R-R-Y-L-L-A-G-E-G-M-G-F-S-F-H-E-T-I-I-L-A-G-T-K-T-H-I-H-Y-Q-N-H-L-E-A-V-F-C-V-Q-G-R-G-E-V-E-L-I-P-S-G-E-R-F-L-I-E-E-G-V-M-Y-A-L-D-K-H-D-E-H-Y-L-S-A-S-E-E-M-R-L-I-C-V-F-N-P-P-L-Q-G-N-E-V-H-D-E-K-G-V-Y-P-L-K-K-G-Q"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-Y-S-I-V-T-A-L-L-E-L-C-E-N-H-A-K-S-N-K-A-K-K-V-T-K-V-V-V-A-L-G-E-R-S-G-V-E-P-Q-L-L-E-S-A-F-E-V-F-K-L-D-S-V-C-A-E-S-E-L-V-I-E-T-K-P-M-K-F-R-C-R-S-C-G-A-E-F-L-P-K-G-I-D-F-G-S-C-E-V-C-K-A-P-N-P-E-L-V-G-G-K-E-M-H-L-Q-S-L-E-M-E-A-E-D-E-G"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-Q-I-D-D-K-L-L-A-R-L-E-S-L-A-M-I-E-V-P-E-E-K-K-E-S-I-K-A-E-L-G-E-I-V-N-F-V-E-N-L-N-S-L-E-V-E-G-L-E-A-T-F-T-T-L-E-G-K-T-P-M-R-E-D-T-P-M-N-D-E-E-I-P-A-L-I-L-K-H-A-P-Q-S-A-E-N-Y-F-I-V-P-K-I-I-E"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-D-F-D-N-Q-T-D-T-N-L-D-I-T-L-L-E-S-I-A-T-F-L-S-P-R-E-V-E-L-I-L-L-D-D-E-A-M-R-K-I-N-Q-E-H-R-G-I-D-K-S-T-D-V-L-S-F-P-L-E-G-G-D-F-L-P-L-G-S-I-L-L-S-I-D-R-V-R-A-E-A-E-L-R-G-H-S-I-E-A-E-A-A-L-L-F-I-H-G-M-L-H-L-L-G-Y-D-H-E-Y-D-Q-G-E-Q-R-F-K-E-E-E-L-I-T-R-F-G-L-P-S-S-L-I-V-R-T-E-E-L"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-M-E-L-L-K-L-N-I-V-T-P-Q-G-S-I-F-S-G-D-V-K-S-V-T-L-P-G-A-E-G-E-F-G-V-L-P-G-H-A-D-L-L-S-L-L-N-A-G-A-I-E-F-E-K-S-N-G-K-T-E-L-V-A-V-N-W-G-Q-V-K-V-D-A-V-S-V-D-V-L-A-D-G-A-I-A-I-G-G-D-S-E-S-E-V-A-M-A-I-A-N-A-R-T-L-L-E-E-A-T-D-N-N-V-A-I-S-S-V-V-S-R-I-E-S-A-A-K-N-S-L"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-G-I-H-P-N-Y-V-P-C-K-V-T-C-V-T-S-G-K-E-F-E-V-L-S-T-K-P-E-L-R-I-D-I-S-S-F-C-H-P-F-Y-T-G-S-D-K-V-V-D-T-A-G-R-V-E-K-F-K-Q-K-Y-N-M-K"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-V-A-K-G-S-D-F-E-T-E-I-K-E-E-I-I-V-A-E-P-R-R-F-K-V-I-L-L-N-D-D-Y-S-T-M-D-F-V-V-E-V-L-M-V-I-F-N-K-N-F-D-E-A-L-G-V-M-L-K-V-H-N-E-G-R-G-V-C-G-I-Y-P-Y-D-V-A-E-T-K-V-S-Q-V-K-K-K-A-E-E-S-G-F-P-L-R-A-I-L-E-E-C"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-Q-R-M-E-E-I-A-F-K-A-L-N-R-V-N-N-D-R-Y-L-L-A-N-I-L-F-A-R-I-D-E-L-S-K-G-A-K-P-L-V-N-M-D-V-K-K-H-K-L-T-D-I-A-M-T-E-V-A-E-G-K-I-A-L-S-Q-I-D-Q-L"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-M-P-S-M-P-E-L-L-V-I-L-A-I-V-V-L-L-F-G-A-K-K-I-P-D-L-A-K-G-L-G-S-G-I-K-N-F-K-K-A-M-K-E-D-E-E-S-E-V-S-V-T-K-S-E-K-I-E-E-A-P-K-N-E-K-S-A-S-T-P-I-Q-D-T-T-K-Q-A"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-R-V-Y-C-I-S-K-P-E-K-D-A-Y-A-E-L-G-E-H-F-K-K-L-A-R-S-F-N-V-E-L-E-I-L-D-I-F-N-K-Q-I-A-Q-A-Q-K-A-A-N-E-A-E-S-S-L-A-Y-K-E-A-L-Q-R-Y-L-S-G-A-H-N-I-A-L-T-P-E-G-K-L-Y-D-S-H-A-F-S-Q-I-F-H-H-K-Q-E-V-N-F-F-I-G-G-A-Y-G-F-E-P-G-F-L-K-S-C-H-Q-S-L-S-L-S-P-L-T-L-G-H-K-V-A-K-V-V-L-C-E-Q-I-Y-R-G-L-T-I-M-H-N-H-P-Y-H-K"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-G-R-I-L-A-I-D-Y-G-R-K-R-T-G-L-A-V-T-D-P-L-K-I-I-P-G-G-L-T-T-V-P-T-H-T-L-L-D-F-L-R-D-Y-V-S-R-E-P-V-E-R-F-V-L-G-L-P-R-R-M-N-Y-E-E-S-E-S-M-T-Y-I-R-P-F-A-V-K-L-A-Q-A-F-P-S-I-P-I-T-Y-V-D-E-R-F-T-S-R-M-A-Q-R-T-I-L-E-A-G-I-G-K-M-K-R-R-D-K-A-L-V-D-E-V-S-A-V-I-I-L-Q-S-Y-L-D-N-P-D-R"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-L-L-P-I-Y-L-Y-G-H-P-V-L-R-K-V-A-E-D-I-T-P-D-Y-P-K-L-K-E-L-I-A-N-M-T-E-S-M-Y-H-S-D-G-I-G-L-A-A-P-Q-I-G-L-P-I-R-V-L-V-I-D-A-D-P-L-K-E-D-Y-P-E-C-A-G-F-K-R-V-M-I-N-A-H-I-E-E-R-G-E-D-L-C-T-E-Y-E-G-C-L-S-L-P-A-I-H-E-K-V-E-R-P-T-S-I-R-I-R-Y-V-D-E-D-F-Q-P-H-E-E-V-L-Q-G-F-A-A-R-V-V-Q-H-E-Y-D-H-I-D-G-K-L-F-I-D-H-I-S-P-I-R-K-Q-L-I-K-G-K-L-Q-N-I-I-K-G-K-V-R-T-S-Y-R-V-V-T-A-P-T-G-K-K-R"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-V-L-L-V-V-G-K-T-D-S-K-L-M-V-Q-A-T-E-E-Y-I-R-R-L-S-H-Y-V-S-F-E-V-E-V-I-P-D-V-R-L-G-S-K-L-S-S-E-Q-Q-K-D-A-E-G-R-E-I-L-A-R-L-R-P-S-D-S-T-V-L-L-D-E-R-G-R-E-Y-S-S-M-E-F-S-A-F-L-Q-K-K-M-L-I-G-T-R-R-M-V-F-V-I-G-G-P-Y-G-F-S-P-A-V-Q-E-A-V-T-D-R-I-S-L-S-R-M-T-F-S-H-Q-M-I-R-L-F-F-T-E-Q-V-Y-R-A-M-T-I-L-N-H-E-P-Y-H-H-E"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-Q-Q-L-V-R-K-G-R-E-S-F-A-D-K-S-K-S-P-A-L-N-S-C-P-Q-R-R-G-V-C-V-R-V-Y-T-T-T-P-K-K-P-N-S-A-M-R-K-V-A-R-V-R-L-T-N-S-K-E-V-N-A-Y-I-P-G-E-G-H-N-L-Q-E-H-S-I-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-T-A-G-V-N-G-R-T-Q-R-R-S-K-Y-G-A-K-R-P-K-P-G-Q-A-P-A-A-K-G-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-A-K-P-K-K-R-Q-I-L-P-D-P-V-Y-G-D-V-R-V-T-K-F-V-N-H-L-M-Y-D-G-K-K-N-T-A-F-S-I-F-Y-G-A-L-D-I-V-K-T-K-H-S-N-E-E-K-S-A-L-E-I-W-K-A-A-L-D-N-I-T-P-Q-V-E-V-K-S-R-R-I-G-G-A-T-F-Q-V-P-T-E-I-R-P-E-R-K-E-S-I-S-M-K-N-L-I-L-Y-A-R-K-R-G-G-K-T-M-A-D-K-L-A-A-E-I-V-D-A-F-N-N-Q-G-A-A-F-K-R-K-E-D-M-H-R-M-A-E-A-N-R-A-F-A-H-F-R-F"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-Q-K-I-R-I-K-L-K-S-Y-D-Y-M-L-V-D-K-S-A-E-K-I-V-K-T-V-K-A-A-G-A-M-V-S-G-P-I-P-L-P-T-H-K-R-I-F-T-V-N-R-S-T-F-V-N-K-K-S-R-E-Q-F-E-L-S-S-Y-K-R-L-I-D-I-Y-N-S-T-A-K-T-V-D-A-L-M-K-L-E-L-P-S-G-V-E-V-E-I-K-V"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-L-K-K-G-P-Y-I-N-L-K-L-E-K-K-V-L-A-M-N-E-S-G-K-K-A-V-I-K-T-W-A-R-A-S-M-I-S-P-D-F-V-G-H-T-I-A-V-H-N-G-N-K-F-I-P-V-F-V-T-E-N-M-V-G-H-K-L-G-E-F-S-P-T-R-T-F-R-G-H-A-G-N-K-K-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-G-A-R-K-H-N-S-A-E-A-R-K-E-A-L-K-Q-M-Y-F-A-K-L-R-N-V-P-T-S-P-R-K-M-R-L-V-A-D-M-I-R-G-M-E-V-N-R-A-L-G-V-L-K-F-S-N-K-E-A-S-A-R-V-E-K-L-L-R-S-A-V-A-N-W-E-E-K-N-E-R-K-A-E-E-G-E-L-F-V-S-R-I-C-V-D-G-A-S-T-L-K-R-L-R-P-A-P-Q-G-R-G-Y-R-I-R-K-R-S-N-H-V-T-I-Y-V-D-T-L-N-N-D-N-N"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-K-T-K-F-R-R-Q-Q-K-G-R-M-K-G-F-A-Q-R-G-N-Q-L-S-F-G-S-F-G-I-K-S-L-Q-S-K-W-I-T-G-R-Q-I-E-A-A-R-I-A-V-T-R-Y-M-Q-R-Q-G-Q-V-W-V-R-I-F-P-D-K-P-I-T-K-K-G-E-G-V-R-M-G-K-G-K-G-A-P-E-G-F-V-A-P-I-T-P-G-R-I-I-F-E-V-E-G-V-P-Y-E-I-A-K-E-A-L-R-L-A-A-Q-K-L-P-V-T-T-K-F-V-V-R-H-D-Y-D-I-Q-N-Q-N-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-N-L-R-K-E-R-V-G-V-V-S-S-N-K-M-D-K-T-I-T-V-A-V-K-W-K-E-K-H-P-I-Y-G-K-F-V-N-K-T-K-K-Y-H-A-H-D-E-K-N-E-C-G-I-G-D-T-V-R-I-M-E-T-R-P-L-S-R-T-K-R-W-R-L-T-E-I-I-E-R-A-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-V-V-A-D-N-S-G-A-K-E-A-L-C-I-R-V-L-G-G-T-R-R-R-Y-A-S-V-G-D-I-I-V-V-S-V-K-S-V-I-P-S-S-D-I-K-K-G-A-V-S-K-A-V-I-V-R-T-K-K-E-V-R-R-P-D-G-S-Y-I-R-F-D-D-N-A-C-V-L-L-N-A-A-G-D-I-R-G-S-R-I-F-G-P-V-A-R-E-L-R-G-T-N-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-K-L-H-I-K-K-G-D-T-V-M-V-I-S-G-E-D-K-G-H-S-G-R-V-L-E-V-L-V-K-E-Q-R-A-I-V-E-G-L-N-M-I-K-K-H-A-K-P-S-A-K-N-P-Q-G-G-I-I-S-K-E-A-P-I-H-I-S-N-L-N-V-V-D-P-K-T-G-K-A-T-R-I-G-R-R-L-N-E-N-G-K-L-V-R-Y-A-K-K-S-G-E-E-I-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-A-T-A-N-L-K-K-D-Y-Q-E-R-I-V-P-A-L-M-K-Q-F-G-Y-T-S-V-M-Q-V-P-V-L-K-K-I-V-I-N-Q-G-L-G-M-A-T-G-D-K-K-I-I-D-V-A-V-S-E-L-T-A-I-T-G-Q-K-A-V-P-T-V-S-K-K-D-I-S-N-F-K-L-R-K-K-M-P-I-G-V-M-V-T-L-R-R-E-Q-M-Y-E-F-L-E-R-L-V-R-I-A-L-P-R-I-R-D-F-K-G-I-E-S-K-L-D-G-R-G-N-Y-T-L-G-I-N-E-Q-I-I-F-P-E-I-N-I-D-A-I-T-K-I-L-G-M-N-I-T-F-V-T-S-A-Q-S-D-E-E-G-Y-A-L-L-K-E-F-G-L-P-F-K-N-A-K-K-Q-N"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-E-S-M-K-A-R-E-V-K-R-A-K-L-V-A-K-Y-A-A-K-R-A-A-L-K-A-E-G-N-Y-E-A-L-Q-L-L-P-K-N-A-S-P-V-R-L-H-N-R-C-S-M-T-G-R-P-K-G-Y-M-R-Q-F-G-I-S-R-I-Q-F-R-E-M-A-S-A-G-L-I-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-D-P-I-A-D-Y-L-T-R-L-R-N-A-I-M-A-G-H-R-V-V-S-V-P-A-S-N-I-K-K-E-I-T-K-I-L-F-D-K-G-Y-I-L-N-Y-K-F-E-E-N-D-S-Q-G-I-I-K-V-A-L-K-Y-D-L-A-H-K-V-N-A-I-K-K-L-K-R-V-S-R-P-G-L-R-K-Y-V-G-Y-R-D-M-P-R-V-L-N-G-L-G-I-A-I-V-S-T-P-R-G-V-M-T-D-K-E-A-R-E-L-K-V-G-G-E-V-L-C-Y-V-Y"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-L-P-I-S-I-P-A-G-V-T-V-S-H-K-D-E-I-V-T-V-K-G-P-K-G-E-L-S-Q-Y-V-D-P-R-I-T-V-V-I-E-G-G-M-I-H-L-E-R-K-T-D-D-R-I-E-R-S-L-H-G-L-Y-R-S-L-I-N-N-M-V-Q-G-V-S-A-G-F-K-R-E-L-E-L-V-G-V-G-Y-R-A-S-N-Q-G-Q-L-L-E-L-S-L-G-F-T-H-S-I-F-M-Q-L-P-K-E-V-T-V-E-T-K-S-E-R-N-K-N-P-L-I-I-L-E-S-A-D-K-Q-L-L-G-Q-V-C-M-K-I-R-S-F-R-K-P-E-P-Y-K-G-K-G-V-K-F-V-G-E-Q-I-R-R-K-S-G-K-S-A-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-V-T-K-E-Q-R-R-Q-K-I-K-A-R-V-R-G-K-I-S-G-T-Q-E-K-P-R-L-T-V-F-R-S-N-K-Q-I-Y-A-Q-L-I-D-D-I-A-G-R-T-L-A-S-A-S-S-L-K-L-E-M-T-G-S-K-K-E-I-A-A-K-V-G-D-E-I-A-K-A-A-T-E-A-G-I-S-T-V-V-F-D-R-N-G-Y-L-F-H-G-R-I-K-E-L-A-D-A-A-R-K-G-G-L-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-I-V-Y-N-R-V-K-S-T-N-D-L-E-L-K-D-R-L-V-A-I-N-R-V-T-K-V-T-K-G-G-R-T-F-T-F-A-A-I-V-V-V-G-N-E-D-G-V-I-G-W-G-L-G-K-A-G-E-V-P-A-A-I-A-K-G-V-E-A-A-K-K-N-L-I-R-V-P-V-H-N-G-T-I-P-H-E-Q-A-A-S-Y-G-G-A-S-V-F-L-K-P-A-T-T-G-T-G-V-K-A-G-G-A-M-R-A-V-L-D-S-V-G-V-T-D-V-L-A-K-S-K-G-S-S-N-P-H-N-L-V-K-A-T-I-Q-A-L-A-E-M-R-S-P-L-M-V-A-Q-N-R-G-I-S-V-E-K-V-F-K-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-N-L-S-S-L-K-P-A-E-G-A-V-K-S-R-K-R-I-G-R-G-P-G-S-G-L-G-G-T-S-T-R-G-H-K-G-A-K-S-R-S-G-Y-S-K-K-I-G-F-E-G-G-Q-M-P-I-Q-R-R-L-P-K-F-G-F-K-N-I-N-R-V-E-Y-K-P-I-N-L-S-V-L-Q-T-L-S-E-A-N-S-L-T-K-I-S-V-E-D-L-I-A-A-G-L-V-S-R-N-S-L-V-K-I-L-A-N-G-T-V-T-T-A-L-T-V-E-A-H-A-F-S-K-T-A-E-E-A-I-V-R-A-G-G-S-V-V-K-L"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-Q-T-A-I-E-Q-D-G-V-I-L-E-A-L-S-N-A-M-F-K-V-E-L-Q-N-G-H-V-I-T-A-H-I-S-G-K-M-R-M-H-Y-I-K-I-L-P-G-D-K-V-K-V-E-M-S-P-Y-D-L-T-K-G-R-I-S-F-R-Y-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-I-R-I-V-G-V-D-L-P-Q-N-K-R-G-F-I-A-L-T-Y-I-Y-G-I-G-R-S-S-A-I-T-I-L-D-K-A-G-V-D-R-D-I-K-V-K-D-W-S-D-D-Q-A-A-A-I-R-D-V-I-G-A-G-Y-K-V-E-G-D-L-R-S-E-V-Q-L-N-I-K-R-L-M-D-I-G-C-Y-R-G-I-R-H-R-I-G-L-P-L-R-G-Q-S-T-K-N-N-A-R-T-R-K-G-K-K-K-T-V-A-N-K-K-K-A-T-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-K-A-V-A-K-K-K-V-V-R-V-E-A-V-G-Q-A-H-I-H-S-S-F-N-N-I-I-I-S-L-A-N-S-E-G-Q-V-I-S-W-S-S-A-G-K-M-G-F-R-S-S-K-K-N-T-P-Y-A-A-Q-M-A-A-Q-D-C-A-K-V-A-Y-D-M-G-L-R-K-V-T-V-Y-V-K-G-P-G-N-G-R-E-S-A-I-R-T-I-H-G-A-G-I-E-V-M-E-I-I-D-V-T-P-M-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-E-I-K-E-L-I-A-K-A-T-A-N-M-E-K-A-V-E-Y-L-D-E-Q-L-S-H-V-R-A-G-K-A-S-P-K-L-L-D-G-I-M-V-M-Y-Y-G-N-A-T-P-L-T-Q-V-A-S-I-N-T-P-D-A-K-T-I-V-V-T-P-W-E-R-S-L-I-K-D-I-E-K-A-I-M-D-S-P-L-G-I-T-P-E-N-N-G-E-L-I-R-L-G-L-P-P-L-T-E-E-R-R-R-Q-L-V-K-Q-T-K-G-D-A-E-D-A-K-V-S-V-R-N-A-R-R-D-A-I-D-A-I-K-K-S-V-K-T-D-G-T-P-E-D-V-A-K-D-A-E-A-E-M-Q-K-V-H-D-R-Y-I-K-K-I-D-E-L-F-A-E-K-E-K-E-I-M-T-V"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-K-Q-K-N-N-R-E-R-T-P-Q-P-E-Q-D-T-E-R-D-E-Q-L-T-N-S-H-E-N-D-I-D-S-A-P-A-A-E-E-N-D-K-V-A-D-P-V-E-Q-L-T-A-Q-L-A-A-L-N-D-T-H-L-R-L-M-A-E-Y-D-N-Y-R-K-R-T-L-K-E-K-S-E-L-I-R-N-G-G-E-K-V-L-V-D-L-L-P-V-I-D-D-F-E-R-A-L-S-N-L-G-D-M-S-E-P-A-A-I-K-E-G-V-E-L-I-Y-S-K-F-M-D-Y-L-Q-K-Q-G-V-K-K-I-E-T-A-D-L-P-F-D-A-D-L-C-D-A-V-A-M-I-P-A-P-S-A-E-Q-K-G-K-V-I-D-C-V-K-T-G-Y-T-L-N-D-K-V-I-R-H-A-H-V-V-V-G-E"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-E-V-E-K-K-V-I-D-L-V-V-D-K-L-N-V-E-A-S-E-V-T-R-E-A-S-F-S-N-D-L-G-A-D-S-L-D-T-V-E-L-M-M-N-F-E-K-E-F-N-M-S-I-P-D-D-Q-A-Q-E-I-K-T-V-G-D-A-I-D-Y-I-E-K-N-L-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-Y-L-D-S-A-K-K-A-E-L-F-E-K-Y-G-K-S-V-K-D-T-G-S-P-E-S-Q-I-A-L-F-T-F-R-I-A-H-L-T-E-H-L-R-Q-N-K-K-D-F-A-T-E-R-S-L-K-M-L-V-G-K-R-R-R-M-L-D-Y-L-I-K-V-D-I-E-R-Y-R-A-I-I-K-E-L-G-I-R-R"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-I-S-S-E-K-R-I-R-Q-T-N-A-R-R-L-H-N-R-Y-Y-A-R-T-A-R-N-A-V-K-A-F-R-A-L-T-D-R-T-E-A-E-K-K-Y-P-V-L-A-S-M-L-D-R-L-A-G-K-N-I-I-H-K-N-K-A-A-N-L-K-S-K-L-A-R-R-I-N-T-L-A"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-A-T-A-Y-H-N-L-S-D-Y-D-Y-E-S-V-P-C-G-K-D-L-R-I-G-I-A-V-A-E-W-N-H-N-I-T-E-P-L-M-K-G-A-I-D-T-L-L-E-H-G-V-S-A-D-N-I-I-V-Q-H-V-P-G-T-F-E-L-T-Y-A-S-A-Y-L-A-E-Q-H-E-V-D-A-V-I-A-I-G-C-V-V-R-G-D-T-P-H-F-D-Y-I-C-Q-G-V-T-Q-G-I-T-Q-L-N-I-D-G-F-V-P-V-I-F-G-V-L-T-T-E-T-M-L-Q-A-E-E-R-A-G-G-K-H-G-N-K-G-T-E-A-A-V-T-A-L-K-M-A-G-L-E-R-I"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-I-D-L-D-S-L-E-H-I-G-V-L-G-K-P-H-G-V-Q-G-E-C-N-A-R-L-T-A-D-L-S-T-L-F-E-E-E-E-R-L-F-L-F-F-E-L-D-A-L-P-V-P-F-R-L-I-G-Y-R-E-K-T-D-D-I-T-L-L-R-F-A-G-I-E-S-K-E-E-M-E-Q-Y-T-G-V-S-L-F-M-E-R-R-Y-F-D-T-D-S-I-E-F-T-W-E-H-F-I-G-F-T-V-F-D-R-E-G-C-F-V-G-T-I-D-D-V-D-E-S-T-L-N-V-L-L-S-I-T-T-P-E-G-K-E-L-L-L-P-V-A-E-D-L-L-E-E-I-D-V-P-N-R-K-L-T-M-I-I-P-D-G-L-L-Q-L"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-K-K-F-I-Q-D-F-K-A-F-A-L-K-G-N-V-V-D-M-A-V-G-V-I-I-G-G-A-F-G-K-I-V-T-S-L-V-N-D-I-M-M-P-P-I-S-L-L-T-G-G-V-N-F-T-D-L-K-L-V-L-S-K-A-V-V-E-G-G-E-V-V-K-P-E-V-S-W-N-Y-G-N-F-I-Q-T-T-V-D-F-L-I-L-A-F-V-I-F-L-M-I-K-A-I-M-A-A-K-R-K-E-E-E-A-P-A-A-P-A-P-T-P-P-E-I-E-L-L-T-E-I-R-D-L-L-K-K-Q"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-T-T-A-D-F-R-N-G-M-C-L-E-I-E-G-Q-Y-Y-F-I-V-E-F-L-H-V-K-P-G-K-G-P-A-F-V-R-T-K-L-K-N-V-T-T-G-R-I-L-D-K-T-W-N-S-G-V-K-V-E-E-V-R-I-E-R-R-P-Y-Q-Y-L-Y-Q-D-E-M-G-Y-N-F-M-H-P-E-T-F-E-Q-I-T-I-P-G-A-S-I-D-G-V-Q-F-L-K-D-G-D-M-V-E-V-M-V-H-A-T-S-E-T-V-L-T-C-E-L-P-P-H-V-K-L-R-V-T-Y-T-E-P-G-L-K-G-D-T-A-T-N-T-L-K-P-A-T-V-E-T-G-A-E-V-R-V-P-L-F-I-Q-E-G-E-L-I-E-V-D-T-R-D-G-S-Y-I-G-R-V-K-E"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-S-V-N-H-V-A-S-R-A-K-R-K-R-I-L-K-L-T-R-G-Y-F-G-A-R-K-N-V-W-T-V-A-K-N-T-W-E-K-G-L-T-Y-A-Y-R-D-R-K-S-K-K-R-N-F-R-A-L-W-I-Q-R-I-N-A-A-A-R-L-E-G-M-S-Y-S-R-L-M-G-A-L-H-A-N-G-I-E-I-N-R-K-V-L-A-D-L-A-M-N-H-P-E-A-F-R-A-I-V-A-K-V-K-N"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-I-K-I-I-N-R-S-H-H-P-L-P-T-Y-A-T-S-A-S-A-G-M-D-L-R-A-S-I-E-E-P-I-T-L-L-P-L-E-R-R-L-I-P-T-G-L-F-I-E-L-P-V-G-Y-E-A-Q-I-R-P-R-S-G-L-A-L-R-H-G-I-T-L-V-N-S-P-G-T-I-D-A-D-Y-R-G-E-I-G-I-I-M-I-N-L-S-N-T-P-F-T-I-A-D-G-E-R-I-C-Q-L-V-I-A-R-H-E-Q-A-E-W-V-L-T-D-E-L-A-D-T-E-R-G-A-G-G-F-G-H-T-G-K-E"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-K-T-P-A-E-L-K-Y-S-K-D-H-E-W-A-R-Q-E-G-D-V-V-F-I-G-I-T-D-Y-A-Q-G-E-L-G-E-I-V-Y-V-D-V-T-T-E-G-E-T-L-E-A-D-E-V-F-G-S-I-E-A-V-K-T-V-S-D-L-M-M-P-I-A-G-E-V-L-E-V-N-P-D-L-E-E-Q-P-E-L-V-N-S-D-P-Y-G-A-G-W-I-I-K-V-K-A-A-N-A-A-D-F-D-N-L-L-S-A-A-E-Y-E-K-L-I-A-Q"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-K-E-D-V-V-N-L-G-Y-K-D-D-I-V-T-V-K-D-G-Y-G-R-N-F-L-I-P-Q-G-K-A-V-I-A-S-E-S-A-K-K-V-L-A-E-N-L-R-Q-R-A-H-K-I-A-Q-I-K-K-E-A-E-E-K-A-A-S-M-Q-G-I-S-L-T-I-K-A-K-T-S-S-T-G-T-I-F-G-S-V-T-N-I-Q-I-A-E-E-L-A-K-K-G-V-E-V-D-R-K-I-I-V-L-K-P-A-V-K-E-V-G-N-Y-T-A-V-V-R-L-H-K-E-V-T-V-E-I-P-F-E-V-V-S-E-N-E-T-I-I-E-A-K-P-E-E-A-P-V-P-V-A-E-E-P-T-A-E-T-E-Q-A-E-V-A-A-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-A-N-N-Q-G-E-I-R-Y-L-T-P-L-S-V-D-T-K-K-K-K-Y-C-R-F-K-K-S-G-I-R-Y-I-D-Y-K-D-P-E-F-L-K-K-F-L-N-E-Q-G-K-I-L-P-R-R-I-T-G-T-S-L-K-F-Q-R-R-V-A-Q-A-V-K-R-A-R-H-L-A-L-L-P-Y-V-T-D-M-M-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-N-N-Y-E-T-V-F-I-L-T-P-V-L-S-D-A-Q-M-K-E-A-V-D-K-F-T-G-L-L-K-Q-E-G-A-V-I-V-N-E-E-N-W-G-L-R-K-L-A-Y-P-I-Q-K-K-S-T-G-F-Y-Q-L-V-E-F-Q-A-N-P-D-V-I-A-K-L-E-T-N-F-R-R-D-E-R-V-I-R-F-L-T-F-R-Q-D-K-F-A-A-E-Y-A-A-K-R-R-S-L-K-A-K-T-E-E-V-K-E-A"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-T-T-A-D-F-R-N-G-M-C-L-E-I-E-G-Q-Y-Y-F-I-V-E-F-L-H-V-K-P-G-K-G-P-A-F-V-R-T-K-L-K-N-V-A-T-G-R-I-L-D-K-T-W-N-S-G-V-K-V-E-E-V-R-I-E-R-R-P-Y-Q-Y-L-Y-Q-D-E-M-G-Y-N-F-M-H-P-E-T-F-E-Q-I-T-I-P-G-A-S-I-D-G-V-Q-F-L-K-D-G-D-M-V-E-A-M-V-H-A-T-S-E-T-V-L-T-C-E-L-P-P-H-V-K-L-R-V-T-Y-T-E-P-G-L-K-G-D-T-A-T-N-T-L-K-P-A-T-V-E-T-G-A-E-V-R-V-P-L-F-I-Q-E-G-E-L-I-E-V-D-T-R-D-G-S-Y-I-G-R-V-K-E"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-T-K-L-I-I-I-S-A-P-S-G-T-G-K-S-T-V-I-E-R-L-L-T-D-R-E-L-N-L-H-F-S-I-S-A-T-S-R-A-P-R-G-E-E-Q-N-G-R-E-Y-Y-F-L-S-P-E-E-F-R-R-R-I-E-A-N-E-F-V-E-Y-E-E-V-Y-R-D-K-Y-Y-G-T-L-K-S-E-V-E-R-I-L-K-E-E-K-N-V-I-F-D-V-D-V-V-G-A-Q-S-I-K-K-Y-Y-G-D-R-A-L-A-I-F-I-L-P-P-S-I-E-E-L-R-S-R-L-Q-K-R-G-T-D-S-M-E-T-I-K-Q-R-V-D-K-A-E-K-E-I-G-Y-A-H-L-F-D-L-R-F-V-N-D-D-L-V-T-C-V-E-Q-I-R-K-A-I-A-Q-F-I-A-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-K-I-N-F-Y-A-E-G-V-S-L-P-R-I-R-R-R-I-V-G-K-W-I-A-E-V-C-S-R-Y-G-K-A-V-G-E-I-S-Y-L-F-C-D-D-E-Y-I-L-K-A-N-Q-E-F-L-D-H-D-Y-Y-T-D-I-I-T-F-D-S-C-E-A-D-T-V-N-G-D-L-L-I-S-L-D-T-V-R-S-N-A-R-A-L-D-L-R-Y-E-D-E-L-H-R-V-I-I-H-G-I-L-H-L-C-G-L-K-D-K-S-K-K-D-E-A-Q-M-R-A-A-E-E-K-A-L-V-M-L-R-E-T-I-G-S-E-L-S-L-L-H-T"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-E-K-I-Q-K-N-I-L-I-K-N-K-R-A-T-F-D-Y-E-I-L-D-V-Y-T-A-G-I-V-L-V-G-T-E-I-K-S-L-R-L-G-K-G-G-L-V-D-T-Y-C-Y-F-H-R-G-E-L-W-V-K-N-M-Y-I-A-E-Y-F-Y-G-T-Y-N-N-H-V-A-R-R-D-R-K-L-L-L-N-R-K-E-L-R-K-L-E-E-A-S-K-S-M-G-T-T-I-V-P-L-K-L-F-I-N-E-R-G-L-A-K-L-Q-I-G-L-A-R-G-K-K-Q-Y-D-K-R-A-S-I-K-E-R-D-D-R-R-E-M-D-R-A-L-K-R"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-E-K-I-P-S-F-Q-L-D-H-I-R-L-K-R-G-I-Y-V-S-R-K-D-Y-I-G-G-E-V-V-T-T-F-D-I-R-M-K-E-P-N-R-E-P-V-L-G-A-P-E-L-H-T-I-E-H-L-A-A-T-Y-L-R-N-H-P-L-Y-K-D-R-I-V-F-W-G-P-M-G-C-L-T-G-N-Y-F-L-M-R-G-D-Y-V-S-K-D-I-L-P-L-M-Q-E-T-F-R-F-I-R-D-F-E-G-E-V-P-G-T-E-P-R-D-C-G-N-C-L-L-H-N-L-P-M-A-K-Y-E-A-E-K-Y-L-R-E-V-L-D-V-A-T-E-E-N-L-N-Y-P-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-D-I-K-A-I-A-E-Q-L-V-N-L-T-V-K-E-V-S-E-L-A-T-I-L-K-E-E-Y-G-I-E-P-A-A-A-A-V-A-V-A-A-A-P-G-A-A-G-A-A-A-E-E-E-K-T-S-F-D-V-V-L-K-S-A-G-A-A-K-L-Q-V-V-K-A-V-K-E-Q-C-G-L-G-L-K-E-A-K-D-L-V-D-A-A-P-S-T-V-K-E-G-V-D-K-A-T-A-E-A-L-K-K-A-L-E-E-A-G-A-E-V-E-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-E-V-A-G-Q-I-K-L-Q-I-K-G-G-A-A-N-P-S-P-P-V-G-P-A-L-G-A-K-G-I-N-I-M-E-F-C-K-Q-F-N-A-R-T-Q-D-K-A-G-K-V-L-P-V-V-I-T-Y-Y-A-D-K-S-F-D-F-I-V-K-T-P-P-V-A-I-Q-L-L-E-A-S-K-Q-K-S-G-S-A-E-P-N-R-K-K-V-A-E-I-T-W-E-Q-V-R-T-I-A-E-D-K-L-V-D-L-N-C-F-D-I-K-A-A-M-K-M-V-A-G-T-A-R-S-M-G-I-A-I-K-G-D-F-P-E"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-K-K-E-E-M-L-V-A-A-I-R-N-G-I-V-I-D-H-I-P-P-T-K-L-F-K-V-A-T-L-L-Q-L-D-D-L-D-K-R-I-T-I-G-N-N-L-R-S-R-S-H-G-S-K-G-V-I-K-I-E-D-K-T-F-E-E-E-E-L-N-R-I-A-L-I-A-P-N-V-R-L-N-I-I-R-D-Y-E-V-V-E-K-R-Q-V-E-V-P-H-E-I-V-G-L-V-R-C-P-N-P-K-C-I-T-N-N-E-P-M-Q-T-R-F-R-V-I-D-A-E-Q-C-T-L-R-C-D-Y-C-E-R-K-L-A-G-D-R-I-E-L-L"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-V-I-V-D-I-Q-G-Q-Q-M-K-V-E-Q-G-R-R-L-F-V-H-H-I-K-D-V-E-S-G-A-S-V-E-F-D-K-V-L-L-V-D-N-N-G-A-I-T-V-G-S-P-L-V-E-G-A-K-V-V-C-E-V-L-T-P-L-V-K-G-D-K-V-L-I-F-H-K-K-R-R-K-G-Y-R-K-L-N-G-H-R-Q-Q-F-T-E-I-L-V-K-E-V-V-A"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-I-D-R-E-Q-I-V-R-I-V-S-D-Y-L-S-T-G-E-T-F-L-V-E-V-A-I-H-P-G-N-R-I-L-V-E-L-D-S-A-Q-G-V-C-I-D-E-C-V-A-L-S-R-H-I-E-S-Q-V-D-R-D-I-E-D-Y-E-L-E-V-G-S-T-G-L-T-S-P-L-K-V-M-R-Q-W-E-N-C-I-D-S-E-L-S-V-L-L-T-N-G-M-K-E-T-G-R-L-I-T-V-A-P-E-A-I-K-L-E-V-V-R-M-V-K-P-E-G-A-K-R-K-K-P-E-T-Q-E-L-T-I-V-M-A-D-I-K-Q-A-V-R-I-I"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-T-S-P-P-T-F-G-L-S-K-S-E-R-L-Y-L-R-D-E-I-N-T-V-F-G-E-G-K-A-F-V-V-Y-P-L-R-V-V-Y-R-L-G-S-E-H-R-V-A-Y-S-S-M-L-V-S-V-A-K-K-R-F-R-R-A-V-K-R-N-R-V-K-R-L-V-R-E-A-Y-R-L-N-K-H-L-L-N-D-V-L-Q-E-R-Q-I-Y-A-T-I-A-F-M-V-V-S-D-E-L-P-D-F-R-T-V-E-R-A-M-Q-K-S-L-I-R-I-A-G-N-V-P-S-S-A-L-K-N-E"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-K-T-F-Q-L-T-G-T-P-R-A-E-F-G-K-K-A-A-K-A-I-R-K-E-D-Q-I-P-A-V-L-Y-G-G-K-G-E-G-V-N-F-I-V-S-Q-D-A-V-R-N-L-I-Y-S-P-E-I-F-L-V-E-L-T-V-E-G-S-G-S-Y-K-A-I-L-K-E-I-Q-F-H-P-V-T-D-R-I-I-H-I-D-F-L-Q-V-T-D-E-K-P-V-V-M-E-V-P-V-V-L-T-G-H-A-E-G-V-K-A-G-G-K-L-S-L-E-M-R-K-L-K-V-K-A-L-Y-S-E-I-P-E-K-L-D-I-D-V-S-D-L-Q-L-G-K-T-I-Q-V-G-E-L-H-F-E-G-L-T-L-M-N-A-K-N-A-V-V-C-A-V-K-L-T-R-A-A-R-G-A-A-V-K-K-Q"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-Y-L-I-V-G-L-G-N-I-G-G-E-Y-N-G-T-R-H-N-V-G-F-R-M-V-N-A-L-A-E-D-G-G-V-Q-F-V-E-A-R-Y-G-A-I-A-R-M-R-V-K-N-A-E-L-I-L-L-K-P-N-T-Y-M-N-L-S-G-N-A-V-R-Y-W-M-Q-Q-E-N-I-P-R-E-Q-V-L-V-L-V-D-D-L-A-L-P-F-G-T-L-R-L-K-P-K-G-S-D-A-G-H-N-G-L-K-N-I-A-E-V-M-G-S-I-D-Y-A-R-L-R-F-G-L-G-D-E-F-S-K-G-R-Q-V-D-F-V-L-G-R-F-T-P-E-E-E-E-K-L-P-E-L-T-K-H-A-V-E-I-I-K-S-F-C-L-A-G-I-Q-R-T-M-N-R-Y-N"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-L-T-G-L-F-F-G-S-F-N-P-M-H-I-G-H-L-A-L-A-N-Y-L-T-E-Y-T-P-I-G-Q-L-W-F-V-P-S-P-L-N-P-L-K-N-T-Q-E-L-L-P-Y-D-L-R-C-E-L-I-E-Q-A-I-R-K-D-I-R-F-Q-V-L-R-I-E-E-L-L-P-S-P-H-Y-T-I-R-T-L-R-A-L-S-M-L-Y-P-H-H-R-F-A-L-L-I-G-A-D-N-W-Q-S-F-D-R-W-K-D-H-H-R-L-M-A-K-Y-E-L-I-I-Y-P-R-F-G-Y-E-V-D-D-T-T-L-P-T-G-C-R-Y-I-H-D-A-P-R-I-E-I-S-S-T-Q-I-R-T-S-I-L-E-G-K-D-L-R-Y-W-L-P-L-P-E-S-Q-D-V-I-A-S-A-L-Q-S-C-L-S-P-K-R"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-D-F-I-K-I-V-N-E-E-F-K-S-G-K-E-H-P-K-F-N-S-G-D-T-I-T-V-E-Y-R-I-K-E-G-N-K-E-R-I-Q-K-Y-R-G-V-V-I-R-I-S-G-H-G-D-K-K-R-F-T-V-R-K-I-S-D-G-I-G-V-E-R-I-F-P-I-E-S-P-F-I-E-N-I-T-V-E-K-Y-G-K-V-R-R-A-K-L-Y-Y-L-R-G-L-T-G-K-K-A-R-I-K-E-R-R-V-A-L-S-S-K-D"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-E-Q-S-N-T-E-M-A-F-Q-I-Q-R-I-Y-T-K-D-I-S-F-E-A-P-N-A-P-Q-V-F-Q-Q-E-W-Q-P-E-V-K-L-D-L-D-T-A-S-S-E-L-A-Q-G-V-Y-E-V-V-L-R-V-T-V-T-A-A-L-G-E-E-T-A-F-L-C-E-V-Q-Q-G-G-I-F-S-I-D-G-I-E-G-T-Q-L-A-H-C-L-G-A-Y-C-P-N-I-L-F-P-Y-A-R-E-C-I-T-S-L-V-S-R-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-M-N-Y-L-Q-Q-Q-A-E-Q-S-Q-G-G-E-Q-T-E-Q-E-A"} +{"text": "### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-F-E-V-F-E-K-L-E-A-K-V-Q-Q-A-I-D-T-I-T-L-L-Q-M-E-I-E-E-L-K-E-K-N-R-S-L-S-Q-E-I-Q-N-A-T-S-G-R-E-S-L-A-H-E-N-E-Q-L-K-Q-E-Q-Q-V-W-Q-E-R-L-R-A-L-L-G-K-M-E-D-V-Q"} +{"text": "### FUNCTION Globally modulates RNA abundance by binding to RNase E and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome Modulates RNA-binding and helicase activities of the degradosome ### SEQUENCE -M-K-Y-D-T-S-E-L-C-D-I-Y-Q-E-E-V-N-V-V-E-P-M-F-S-N-F-G-G-R-T-S-F-G-G-Q-I-I-T-V-K-C-F-E-D-N-G-L-L-Y-D-L-L-E-D-N-G-H-G-R-I-L-L-V-D-G-G-G-S-V-R-Q-A-L-I-N-A-E-L-A-Q-L-A-V-Q-N-G-W-E-G-I-V-V-Y-G-A-V-R-Q-V-D-Q-L-A-E-F-D-L-G-I-Q-A-I-A-A-I-P-A-G-C-R-D-E-G-T-G-A-S-D-I-R-V-N-F-G-G-V-T-F-F-S-G-D-Y-L-Y-A-D-N-T-G-I-I-L-S-E-E-P-L-E-L-D-D-N-E-E-D-E-I-I"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-G-I-H-P-K-Y-E-E-I-T-A-T-C-S-C-G-S-V-I-Q-V-R-S-T-A-G-H-A-L-N-L-D-V-C-G-Q-C-H-P-F-Y-T-G-K-Q-R-D-V-A-T-G-G-R-V-D-R-F-K-K-R-F-N-V-P-G-V-S-K"} +{"text": "### FUNCTION This regulatory protein, when combined with SAM represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-A-E-W-N-G-E-Y-V-S-P-Y-A-E-H-G-K-K-S-E-Q-V-K-K-I-T-V-S-I-P-L-K-V-L-R-I-L-T-D-E-R-T-R-R-Q-V-N-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-F-T-G-Q-P-L-P-D-D-A-D-L-R-K-E-R-N-D-E-I-P-E-E-A-K-K-I-M-R-E-L-G-I-D-P-D-T-W-E-Y"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-R-E-E-R-L-L-K-V-L-R-A-P-H-V-S-E-K-A-S-T-A-M-E-K-S-N-A-I-V-L-K-V-A-K-D-A-T-K-A-E-I-K-A-A-V-Q-K-L-F-E-V-E-V-E-G-V-N-T-L-L-V-K-G-K-T-K-R-H-G-Q-R-I-G-R-R-S-D-W-K-K-A-Y-V-T-L-K-E-G-Q-N-M-D-F-I-G-G-A-E"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-V-E-K-A-V-E-S-G-D-K-K-P-I-K-T-W-S-R-R-S-T-I-F-P-N-M-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-F-V-S-D-E-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-A-A-D-K-K-A-K-K-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-I-A-K-H-R-H-A-R-S-S-A-Q-K-V-R-L-V-A-D-L-I-R-G-K-K-V-S-Q-A-L-E-T-L-T-Y-T-N-K-K-A-A-G-L-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-D-G-A-D-I-D-D-L-K-V-T-K-I-F-V-D-E-G-P-T-M-K-R-I-M-P-R-A-K-G-R-A-D-R-I-L-K-R-S-S-H-I-T-V-V-V-S-D-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-M-H-K-G-R-N-R-G-L-A-A-G-A-D-V-S-F-G-T-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-A-I-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-V-L-Y-E-M-D-G-V-P-E-E-L-A-R-E-A-F-K-L-A-A-A-K-L-P-I-K-T-T-F-V-T-K-T-V-M"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-T-D-K-I-R-T-L-Q-G-R-V-V-S-D-K-M-E-K-S-I-V-V-A-I-E-R-K-V-K-H-P-L-Y-G-K-F-I-K-R-T-T-K-L-H-V-H-D-E-N-N-E-C-G-I-G-D-V-V-E-I-R-E-T-R-P-L-S-K-T-K-S-W-T-L-V-R-V-V-E-K-A-I-L"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-E-Q-T-M-L-N-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-H-V-G-D-I-I-K-V-T-I-K-E-A-I-P-R-G-K-V-K-K-G-D-V-L-K-A-V-V-V-R-T-R-K-G-V-R-R-P-D-G-S-V-I-R-F-D-G-N-A-C-V-L-L-N-N-T-S-E-Q-V-I-G-T-R-I-F-G-P-V-T-R-E-L-R-N-E-K-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-D-D-E-V-I-V-L-T-G-K-D-K-G-K-R-G-K-V-K-Q-V-L-S-T-G-K-V-I-V-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-L-N-Q-P-G-G-I-V-E-K-E-A-A-I-Q-V-S-N-V-A-I-F-N-A-A-T-G-K-A-D-R-V-G-F-R-F-E-D-G-K-K-I-R-F-F-K-S-N-S-E-T-I-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-K-D-E-V-V-Q-K-L-M-T-Q-F-G-Y-N-S-V-M-Q-V-P-R-V-E-K-I-T-L-N-M-G-V-G-E-A-I-A-D-K-K-L-L-D-N-A-A-A-D-L-A-A-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-V-A-G-F-K-I-R-Q-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-E-F-L-E-R-L-I-S-I-A-V-P-R-I-R-D-F-R-G-L-S-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-Y-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-T-A-K-S-D-D-E-G-R-A-L-L-A-A-F-N-F-P-F-R-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-D-V-K-R-A-K-L-A-E-K-F-F-T-K-R-V-E-L-K-A-V-I-S-D-V-N-A-S-D-E-E-R-W-N-A-V-L-K-L-Q-T-L-P-R-D-S-S-P-S-R-Q-R-N-R-C-R-Q-T-G-R-P-H-A-F-L-R-K-F-G-L-S-R-I-K-V-R-E-A-A-M-R-G-E-I-P-G-L-K-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-A-D-M-L-T-R-I-R-N-G-Q-A-A-N-K-V-A-V-T-M-P-S-S-K-L-K-V-A-I-A-K-V-L-K-E-E-G-Y-I-E-D-Y-K-I-E-G-D-T-K-P-E-L-E-L-V-L-K-Y-F-Q-G-K-A-V-V-E-S-I-Q-R-V-S-R-P-S-L-R-I-Y-K-K-K-D-E-L-P-Q-V-M-A-G-L-G-I-A-V-V-S-T-S-K-G-V-M-T-D-R-A-A-R-Q-A-G-L-G-G-E-I-L-C-Y-V-A"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-V-I-P-T-D-V-E-V-K-L-D-G-Q-V-I-S-I-K-G-K-N-G-E-L-S-R-T-I-H-S-A-V-E-V-K-H-A-D-N-Q-L-T-F-A-P-R-D-G-Y-V-D-G-W-A-Q-A-G-T-T-R-S-L-M-N-A-M-V-I-G-V-T-E-G-F-T-K-K-L-Q-L-V-G-V-G-Y-R-A-A-V-K-G-N-V-I-N-M-S-L-G-F-S-H-P-V-D-H-E-L-P-A-G-I-T-A-E-C-P-S-Q-T-E-I-V-L-K-G-A-D-K-Q-V-I-G-Q-V-A-A-E-L-R-A-Y-R-R-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-V-V-R-I-K-E-A-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-A-A-R-I-R-R-A-T-R-A-R-R-K-L-Q-E-L-G-A-T-R-L-V-V-H-R-T-P-R-H-I-Y-A-Q-V-I-A-P-N-G-S-E-T-L-V-A-A-S-T-T-E-K-A-I-N-E-Q-L-K-Y-T-G-N-K-E-A-A-A-A-V-G-K-A-I-A-E-R-A-L-E-K-G-I-K-D-V-S-F-D-R-S-G-F-Q-Y-H-G-R-V-Q-A-L-A-D-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-H-I-E-K-Q-A-G-E-L-Q-E-K-L-I-A-V-N-R-V-S-K-T-V-K-G-G-R-I-F-S-F-T-A-L-T-V-V-G-D-G-N-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-N-M-K-T-V-A-L-N-S-G-T-L-Y-H-P-V-K-G-A-H-T-G-S-R-V-F-M-Q-P-A-H-E-G-T-G-I-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-R-N-V-L-A-K-T-Y-G-S-T-N-P-I-N-V-V-R-A-T-L-D-A-L-D-S-M-K-S-P-E-M-V-A-A-K-R-G-K-S-V-E-E-I-L-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-S-P-A-D-G-S-K-H-A-P-K-R-V-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-K-S-R-S-G-G-G-V-R-R-G-F-E-G-G-Q-M-P-L-Y-R-R-L-P-K-F-G-F-T-S-R-K-A-M-V-T-A-E-V-R-L-S-D-F-A-A-V-E-G-D-I-I-D-L-N-A-L-K-A-A-N-I-V-G-T-Q-I-E-F-A-K-V-I-L-S-G-E-I-N-R-A-V-T-V-R-G-L-R-V-T-K-G-A-H-A-A-I-E-A-A-G-G-K-I-E-E"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-T-V-I-A-L-T-S-I-Y-G-I-G-K-T-R-S-Q-A-I-C-A-A-A-G-I-A-E-H-V-K-I-S-E-L-S-E-E-Q-I-D-K-L-R-D-E-V-A-K-Y-V-V-E-G-D-L-R-R-E-V-T-L-S-I-K-R-L-M-D-L-G-T-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-A-P-I-R-A-R-K-R-V-R-K-Q-V-S-D-G-V-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-G-W-A-T-A-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-R-C-A-E-A-V-K-E-Y-G-I-K-N-L-E-V-M-V-K-G-P-G-P-G-R-E-S-T-I-R-A-L-N-A-A-G-F-R-I-T-N-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-V-L-Q-V-L-H-Y-P-D-E-R-L-R-T-I-A-T-P-V-E-T-V-D-A-E-I-R-R-I-I-D-D-M-F-E-T-M-Y-A-E-E-G-I-G-L-A-A-T-Q-V-D-I-H-Q-R-I-V-V-I-D-V-S-E-T-R-N-E-R-L-V-L-I-N-P-E-L-L-E-K-S-G-E-T-G-I-E-E-G-C-L-S-I-P-E-Q-R-A-L-V-P-R-A-E-K-V-K-I-K-A-L-D-Y-N-G-R-P-F-E-L-Q-A-D-D-L-L-A-I-C-I-Q-H-E-M-D-H-L-I-G-K-L-F-V-D-Y-L-S-P-L-K-R-Q-R-I-R-Q-K-V-E-K-L-D-K-Q-K-A-R-T-K"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-D-S-E-F-H-Q-L-A-D-Q-L-I-L-Y-I-E-G-Q-L-D-N-Y-D-G-N-A-D-I-D-C-E-T-N-G-G-V-M-T-L-S-F-D-N-D-S-K-I-I-I-N-R-Q-E-P-F-H-Q-I-W-L-A-T-K-G-G-G-Y-H-F-D-Y-K-E-G-Q-W-I-C-D-R-S-G-D-N-F-L-T-M-L-A-Y-A-I-T-E-Q-S-G-E-Q-F-S-F-P"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-S-K-S-E-H-N-L-I-W-I-D-L-E-M-T-G-L-D-P-E-R-D-R-I-I-E-I-A-T-I-V-T-D-A-N-L-N-I-L-D-E-G-P-V-I-A-V-H-Q-S-D-E-Q-L-A-L-M-D-K-W-N-V-R-T-H-T-G-S-G-L-V-E-R-V-K-A-S-K-I-D-D-R-E-A-E-K-A-T-I-E-F-L-E-K-W-V-P-A-G-A-S-P-I-C-G-N-S-V-S-Q-D-R-R-F-L-F-R-Y-M-P-E-L-E-A-Y-F-H-Y-R-Y-L-D-V-S-T-L-K-E-L-A-R-R-W-K-P-E-I-L-A-G-L-K-K-Q-N-T-H-Q-A-L-D-D-I-R-E-S-V-A-E-L-A-Y-Y-R-E-H-F-I-Q-L"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-S-R-P-V-S-H-H-S-S-N-T-S-V-G-A-S-V-G-N-Y-H-S-G-G-V-S-A-P-A-A-Q-Q-E-S-D-G-T-E"} +{"text": "### FUNCTION Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress May require iron for activity ### SEQUENCE -M-Q-L-T-S-F-T-D-Y-G-L-R-A-L-I-Y-M-A-S-L-P-Q-S-R-M-T-S-I-S-E-V-T-D-I-Y-G-V-S-R-N-H-M-V-K-I-I-N-Q-L-S-H-L-G-L-V-D-A-V-R-G-K-N-G-G-I-R-L-G-K-P-A-K-D-I-R-I-G-D-V-V-R-A-L-E-P-L-S-L-V-N-C-S-Q-E-S-C-H-I-T-S-A-C-R-L-K-V-V-L-N-Q-A-I-E-R-F-L-E-E-L-D-K-H-T-L-A-D-M-I-E-D-N-I-P-L-Y-K-L-L-L-T-E"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-P-G-M-I-E-R-Y-S-A-T-I-T-N-A-Q-G-Q-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-V-L-M-N-V-E-A-P-Q-E-V-I-D-E-L-E-T-N-F-R-F-N-D-A-V-I-R-S-M-I-M-R-V-K-H-A-V-T-E-A-S-P-M-V-K-A-K-D-E-R-R-S-R-D-Y-S-L-E-D-A-N-M-D-A-E-E-A-G-D-S-E-E"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-T-T-N-R-L-V-L-S-G-T-V-C-K-V-P-I-R-K-V-S-P-A-G-I-P-H-C-Q-F-V-L-E-H-R-S-Q-Q-Q-E-A-G-L-S-R-Q-A-W-C-R-M-P-V-I-A-S-G-Q-L-L-Q-V-L-T-H-S-I-T-V-G-S-R-L-T-V-S-G-F-I-S-C-H-Q-G-R-N-G-L-N-K-L-V-L-H-A-E-Q-I-E-L-I-D-S-G-D"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-D-K-V-A-N-L-G-S-L-G-D-Q-V-N-V-K-P-G-Y-A-R-N-Y-L-V-P-Q-G-K-A-V-P-A-T-K-K-N-I-E-F-F-E-A-R-R-A-E-L-E-A-N-L-A-N-V-L-A-T-A-E-A-R-A-E-K-I-N-A-L-G-S-V-T-I-A-S-K-A-G-D-E-G-K-L-F-G-S-V-G-T-R-D-I-A-D-A-V-T-A-A-G-V-E-V-S-K-S-E-V-R-L-P-N-G-V-L-R-T-I-G-E-H-E-V-N-F-Q-V-H-S-D-V-F-A-K-L-N-V-N-I-V-A-E-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-R-T-P-S-K-Q-E-D-L-V-K-A-F-K-A-L-L-K-E-E-K-F-S-S-Q-G-E-I-V-T-A-L-L-E-E-G-F-E-N-I-N-Q-S-K-V-S-R-M-L-T-K-F-G-A-V-R-T-R-N-A-K-M-E-M-V-Y-C-L-P-A-E-L-G-V-P-T-A-T-S-P-L-K-N-L-V-L-D-V-D-Y-N-H-P-I-V-V-I-R-T-S-P-G-A-A-Q-L-I-A-R-L-L-D-S-L-G-K-S-E-G-I-L-G-S-I-A-G-D-D-T-I-F-V-T-L-T-R-D-S-T-T-E-Q-L-R-G-A-I-L-G-L-F-E-Q-E-L"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-S-E-G-Q-T-I-R-L-E-K-L-D-I-A-T-G-E-T-V-E-F-D-Q-V-L-M-V-A-N-G-D-D-I-K-I-G-A-P-V-V-E-G-V-K-I-K-A-E-V-V-A-H-G-R-G-E-K-I-K-I-V-K-F-R-R-R-K-H-S-R-K-Q-Q-G-H-R-Q-W-F-T-D-V-K-I-T-G-I-A"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-G-L-S-T-L-E-Q-K-L-T-A-M-I-S-A-P-V-E-A-L-G-F-E-L-V-G-L-E-F-I-R-A-R-V-S-T-L-R-I-Y-I-D-S-E-N-G-I-T-V-D-D-C-A-D-V-S-H-Q-V-S-A-V-L-D-V-E-D-P-I-S-V-L-Y-N-L-E-I-S-S-P-G-L-E-R-P-L-F-T-T-E-H-Y-Q-R-F-I-G-E-E-V-S-L-V-L-R-I-A-M-Q-N-R-R-K-W-L-G-I-I-K-T-V-D-G-E-M-I-T-V-T-V-D-G-K-D-E-V-F-A-L-S-N-I-Q-K-A-N-L-V-P-H-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-R-E-F-S-R-T-Q-R-V-A-Q-E-M-Q-K-E-I-A-I-I-L-Q-R-E-V-K-D-P-R-I-G-M-A-T-V-S-G-V-E-V-S-R-D-L-A-Y-A-K-V-F-V-T-F-L-N-V-L-T-E-E-H-D-S-D-V-V-K-N-G-I-K-A-L-N-E-A-S-G-F-I-R-S-L-L-G-K-A-M-R-L-R-V-V-P-E-L-T-F-S-Y-D-N-S-L-V-E-G-M-R-M-S-N-L-V-T-N-V-V-K-N-D-E-Q-R-R-A-S-T-D-H-K-E-E-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-S-T-E-A-K-A-Q-I-I-A-E-F-G-R-D-V-N-D-S-G-S-S-E-V-Q-I-A-L-L-T-A-Q-I-N-H-L-Q-G-H-F-S-E-H-K-K-D-H-H-S-R-R-G-L-L-R-M-V-S-Q-R-R-K-L-L-D-Y-L-K-R-K-N-V-T-S-Y-T-A-L-I-G-R-L-G-L-R-R"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-T-Q-D-H-K-L-Q-V-E-A-I-R-C-G-T-V-I-D-H-I-P-A-Q-V-G-F-K-L-L-S-L-F-K-L-T-E-T-D-Q-R-I-T-I-G-L-N-L-P-S-N-R-L-G-K-K-D-L-I-K-I-E-N-T-F-L-T-E-Q-Q-A-N-Q-L-A-M-Y-A-P-N-A-T-V-N-C-I-E-N-Y-E-V-V-K-K-L-P-I-N-L-P-K-C-I-D-N-V-L-V-C-P-N-S-N-C-I-S-H-N-E-P-V-E-S-S-F-R-V-K-V-T-V-E-D-V-V-L-T-C-K-Y-C-E-K-E-F-D-R-N-V-V-I-L-N-D"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-I-S-I-W-Q-L-L-I-I-A-V-I-V-V-L-L-F-G-T-N-K-L-R-T-L-G-S-D-L-G-A-S-I-K-G-F-K-K-A-I-G-D-D-N-Q-P-Q-Q-A-Q-K-T-S-S-D-A-D-F-E-T-K-N-I-T-E-K-Q-S-V-A-Q-S-E-T-S-E-S-K-N-K-E-Q-V"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-G-E-L-L-L-V-M-V-I-G-L-V-V-L-G-P-E-R-L-P-V-A-V-K-T-V-A-G-W-I-R-A-L-R-S-L-A-A-N-V-Q-N-E-L-V-Q-E-L-K-L-Q-E-L-Q-E-S-L-K-K-V-Q-E-E-A-G-L-Q-N-L-S-P-E-L-K-A-S-M-D-E-L-K-E-A-A-E-S-L-K-K-A-Y-Q-N-E-P-D-A-G-S-M-K-A-S-E-I-N-E-V-A-Q-K-P-A-A-S-Q-V-V-A-S-S-G-P-S-A-L-V-D-D-Q-A-A-S-A-T-K-K-K-T-S-D"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-S-K-N-M-R-Y-P-V-K-F-E-H-D-E-T-G-W-A-V-M-F-P-D-I-P-E-A-L-T-G-G-D-T-R-E-E-A-L-A-M-A-Q-D-A-L-V-T-A-F-D-F-Y-F-E-D-R-R-E-I-P-T-P-S-T-K-G-E-A-F-V-E-V-P-A-S-I-A-A-K-V-L-L-L-N-T-M-L-Q-T-R-T-S-N-A-E-L-A-R-L-L-G-T-R-P-Q-E-I-Q-R-I-V-S-L-S-H-S-T-K-I-D-T-I-A-N-A-L-N-A-L-G-K-H-L-E-L-V-A-I"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-K-Q-S-E-F-R-R-W-L-K-A-Q-G-A-E-F-K-D-G-T-N-H-L-K-V-F-L-N-G-K-Q-T-T-M-P-R-H-P-S-K-E-I-P-E-P-L-R-K-L-I-L-K-Q-P-G-I-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-T-Y-S-T-N-E-F-R-S-G-L-K-I-M-L-D-G-E-P-C-A-I-L-E-S-E-F-V-K-P-G-K-G-Q-A-F-A-R-V-R-I-R-K-L-I-S-G-K-L-L-E-K-T-F-K-S-T-D-S-V-E-S-A-D-V-M-D-M-N-L-T-Y-L-Y-N-D-G-E-F-W-H-F-M-N-N-E-T-F-E-Q-L-A-A-D-E-K-A-V-G-D-N-A-K-W-L-V-E-Q-A-E-C-I-L-T-L-W-N-G-Q-P-I-S-V-T-P-P-N-F-V-E-L-E-I-T-D-T-D-P-G-L-K-G-D-T-A-G-T-G-G-K-P-A-T-L-N-T-G-A-V-V-K-V-P-L-F-V-Q-I-G-E-V-I-K-V-D-T-R-S-G-E-Y-V-S-R-V-K"} +{"text": "### FUNCTION Guanidinium ion exporter Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons ### SEQUENCE -M-S-W-F-V-L-V-I-A-G-L-F-E-V-V-W-A-V-G-L-K-Y-T-H-G-F-T-R-L-I-P-S-L-I-T-A-S-A-V-A-L-S-M-G-L-L-A-Y-A-M-K-G-L-P-I-G-T-A-Y-A-V-W-T-G-I-G-A-V-G-T-A-I-F-G-I-I-V-F-G-E-S-A-S-F-A-R-I-L-S-F-A-L-I-I-A-G-I-I-G-L-K-L-S-S"} +{"text": "### FUNCTION Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion ### SEQUENCE -M-T-T-K-R-K-P-Y-I-R-S-M-A-P-N-W-W-Q-K-L-G-F-Y-R-F-Y-I-L-R-E-S-T-A-V-T-T-M-W-F-S-I-L-L-I-Y-G-L-F-A-L-K-G-G-T-Q-S-W-H-E-F-V-T-F-L-Q-N-P-V-I-L-L-V-N-I-I-T-L-L-G-A-L-L-H-T-K-T-W-F-E-L-A-P-K-A-A-N-I-V-I-K-G-E-K-M-G-S-G-P-V-I-K-L-L-W-A-V-T-I-I-V-T-M-I-I-L-G-I-A-L-L"} +{"text": "### FUNCTION Sulfur carrier protein involved in sulfur trafficking in the cell Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine in tRNA Interacts with IscS and stimulates its cysteine desulfurase activity Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin ### SEQUENCE -M-P-D-V-F-T-H-P-D-K-T-L-D-T-Q-G-L-R-C-P-E-P-V-M-M-V-R-K-T-V-R-H-M-E-A-G-Q-M-L-L-I-L-A-D-D-P-A-T-T-R-D-I-P-S-F-C-R-F-M-E-H-Q-L-V-A-Q-E-T-E-Q-M-P-Y-R-Y-L-V-R-K-K-E-S-Q-L"} +{"text": "### FUNCTION Activates ribosomal RNA transcription Plays a direct role in upstream activation of rRNA promoters ### SEQUENCE -M-F-E-Q-R-V-N-S-D-V-L-T-V-A-T-V-N-S-Q-D-Q-V-T-Q-K-P-L-R-D-S-V-K-Q-A-L-K-N-Y-F-A-Q-L-N-G-Q-D-V-N-D-L-Y-E-L-V-L-A-E-V-E-Q-P-L-L-D-M-V-M-Q-Y-T-R-G-N-Q-T-R-A-A-L-M-M-G-I-N-R-G-T-L-R-K-K-L-K-K-Y-G-M-N"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-T-A-K-P-E-T-V-K-R-D-W-Y-V-V-D-A-D-G-K-T-L-G-R-L-A-T-E-V-A-R-R-L-R-G-K-H-K-A-E-Y-T-P-H-V-D-T-G-D-Y-I-I-I-V-N-A-E-K-V-A-V-T-G-N-K-R-S-D-K-I-Y-Y-H-H-T-G-H-I-G-G-I-K-Q-A-T-F-E-E-M-I-A-R-R-P-E-R-V-I-E-I-A-V-K-G-M-L-P-K-G-P-L-G-R-A-M-Y-R-K-L-K-V-Y-A-G-S-E-H-N-H-A-A-Q-Q-P-Q-V-L-D-I"} +{"text": "### FUNCTION Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein ### SEQUENCE -M-L-D-R-I-K-V-C-F-T-E-S-I-Q-T-Q-I-A-A-A-E-A-L-P-D-A-I-S-R-A-A-I-M-M-V-Q-S-L-L-N-G-N-K-I-L-C-C-G-N-G-G-S-A-A-T-A-Q-R-F-A-A-N-M-I-N-R-F-E-T-E-R-P-S-L-P-A-L-S-L-N-A-D-N-V-V-I-T-A-I-S-S-N-K-Q-H-D-E-I-Y-A-K-Q-V-R-A-L-G-Q-P-G-D-V-L-L-A-I-S-T-H-G-N-S-R-D-I-V-K-A-V-E-A-A-V-T-R-D-M-T-I-V-A-L-T-G-Y-D-G-G-E-L-A-G-L-L-G-P-Q-D-V-E-I-R-I-P-S-H-R-S-T-R-I-Q-E-V-H-M-L-T-V-N-C-L-C-D-L-I-D-N-T-L-F-P-H-Q-D-D"} +{"text": "### FUNCTION Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP ### SEQUENCE -M-N-F-L-A-H-L-H-L-A-T-L-A-D-S-S-L-L-G-N-L-M-A-D-F-V-R-G-N-P-E-G-Q-Y-S-A-D-V-V-A-G-I-R-M-H-R-R-V-D-V-L-T-D-T-H-P-L-V-I-Q-A-R-H-L-F-S-N-S-Y-R-R-V-A-P-I-T-L-D-I-I-W-D-H-F-L-S-L-N-W-D-K-L-V-P-T-Y-S-L-P-A-F-I-H-H-A-R-S-Q-I-E-P-H-L-Y-Y-T-P-E-K-F-Q-E-L-N-A-F-L-W-R-Q-N-W-L-I-R-Y-A-D-L-A-F-I-A-D-V-L-K-G-M-A-R-R-H-P-R-L-S-A-L-S-G-S-F-Q-D-I-E-Q-H-Y-A-D-F-D-A-L-F-W-Q-F-Y-P-Y-M-M-E-K-A-E-N-K-D-F-Y-C-L-P-Q"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-A-A-V-D-T-K-V-I-D-S-R-L-V-G-D-G-S-Q-V-R-R-R-R-Q-C-L-E-C-H-E-R-F-T-T-F-E-M-A-E-L-V-M-P-R-V-I-K-S-D-D-I-R-E-P-F-D-E-E-K-L-R-R-G-M-Q-K-A-L-E-K-R-P-V-S-S-D-D-V-E-M-A-I-S-Y-I-K-S-Q-L-R-A-T-G-E-R-E-V-P-S-K-M-I-G-N-L-V-M-D-E-L-K-K-L-D-K-V-A-Y-I-R-F-A-S-V-Y-R-S-F-E-D-I-R-E-F-G-E-E-I-A-R-L-Q-G"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-P-A-A-R-R-R-A-R-E-C-A-V-Q-A-I-Y-S-W-Q-L-S-G-N-S-I-A-D-V-E-L-Q-F-L-S-E-Q-D-V-T-G-V-D-V-T-Y-F-R-E-L-L-S-G-V-A-V-N-A-A-K-L-D-A-L-M-A-P-Y-L-S-R-Q-L-E-E-L-G-Q-V-E-K-A-I-L-R-I-A-M-F-E-L-S-Y-R-D-D-V-P-Y-K-V-A-I-N-E-A-I-E-L-A-K-V-F-G-A-E-D-S-H-K-F-V-N-G-V-L-D-K-S-G-P-A-V-R-R-K-R"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-A-N-A-Q-Q-L-Q-F-I-K-D-S-I-E-T-I-P-D-Y-P-K-P-G-V-L-F-R-D-I-T-T-L-L-D-N-P-L-A-Y-Q-A-T-I-D-L-L-V-E-R-Y-Q-G-K-G-I-T-K-I-V-G-T-E-A-R-G-F-L-F-G-A-P-V-A-L-R-L-G-V-G-F-I-P-V-R-K-A-G-K-L-P-R-E-T-L-S-E-T-Y-N-L-E-Y-G-T-D-T-L-E-M-H-K-D-S-V-R-E-N-D-K-V-L-V-I-D-D-L-L-A-T-G-G-T-V-E-A-T-V-R-L-I-R-R-L-G-G-E-V-S-E-A-A-F-I-I-G-L-L-G-L-G-G-V-E-R-L-Q-R-Q-G-V-S-S-F-T-L-L-E-F-P-D-H"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-G-G-L-G-N-L-M-K-Q-A-Q-Q-M-Q-D-K-M-Q-K-M-Q-E-E-I-A-S-L-E-V-T-G-E-S-G-A-G-L-V-K-V-T-I-N-G-A-H-N-C-R-R-V-E-I-D-P-S-L-M-E-D-D-K-E-M-L-E-D-L-I-A-A-A-F-N-D-A-A-R-R-I-E-E-T-Q-K-E-K-M-A-G-I-S-S-G-M-Q-L-P-P-G-F-K-M-P-F"} +{"text": "### FUNCTION Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall gene cluster Acts by binding directly to DNA May also regulate the expression of genes outside the dcw cluster ### SEQUENCE -M-F-R-G-A-T-Q-I-N-L-D-S-K-G-R-L-T-V-P-T-R-Y-R-A-M-L-N-E-E-S-Q-G-Q-M-V-C-T-I-D-L-H-Q-P-C-L-L-L-Y-T-L-S-E-W-E-I-I-E-E-K-L-S-R-L-S-S-M-N-P-A-E-R-R-V-Q-R-L-L-L-G-H-A-S-E-C-Q-M-D-S-A-G-R-L-L-L-A-N-T-L-R-Q-H-A-G-L-V-K-E-V-M-L-V-G-Q-F-N-K-F-E-L-W-D-E-Q-A-W-Y-Q-Q-V-K-D-D-I-A-A-E-Q-S-T-Q-E-P-L-S-V-R-L-Q-E-L-S-L"} +{"text": "### FUNCTION Regulates secA expression by translational coupling of the secM secA operon Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation ### SEQUENCE -M-G-I-L-N-L-W-R-Q-F-G-R-R-Y-F-W-S-H-L-L-L-G-V-V-A-A-S-I-G-A-P-T-I-L-A-G-V-T-D-N-I-S-Q-A-N-T-S-P-S-Q-S-W-Q-N-Q-A-L-S-A-F-D-N-L-F-S-L-Q-N-V-Q-H-Q-P-A-N-G-V-N-Y-W-Q-Q-H-A-V-R-N-V-I-R-Q-L-S-F-A-F-S-I-S-Q-P-M-S-D-E-T-A-K-Q-S-I-R-L-S-S-S-N-I-Q-Q-L-V-L-E-T-L-N-T-L-L-I-R-E-P-K-P-P-E-P-V-L-D-I-P-F-L-N-V-A-S-Q-S-S-Y-I-L-T-L-W-I-A-K-A-Q-G-I-R-A-G-P-T-A-Y-L"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-S-E-L-L-T-I-E-C-P-T-C-G-K-T-V-V-W-G-E-I-S-P-Y-R-P-F-C-S-K-R-C-Q-L-I-D-L-G-Q-W-A-N-E-E-K-R-I-P-S-Q-S-E-N-S-D-S-D-D-W-S-G-Q-P-E-Q"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-V-P-A-E-L-K-Y-V-E-S-H-E-W-V-R-A-E-G-N-D-E-Y-T-V-G-I-T-E-H-A-Q-E-L-L-G-D-M-V-F-V-D-L-P-E-V-G-D-Q-I-N-L-G-D-D-C-A-V-V-E-S-V-K-A-A-S-D-I-Y-A-P-L-S-G-K-I-I-A-V-N-D-A-L-N-D-A-P-E-L-V-N-S-E-P-Y-H-E-G-W-L-F-R-I-K-A-S-D-K-S-E-L-S-S-L-L-N-A-E-G-Y-Q-A-L-L-D-E-E-E"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-D-I-D-N-K-A-R-I-H-W-A-C-R-R-G-M-R-E-L-D-I-S-I-M-P-F-F-K-Y-E-Y-D-S-L-S-D-D-D-K-R-L-F-I-R-L-L-A-C-A-D-P-D-L-F-N-W-L-M-N-H-G-R-P-E-D-E-E-L-F-R-M-I-K-L-I-Q-N-R-N-K-D-R-G-P-V-E-V"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-K-Q-S-E-F-R-R-W-L-E-A-Q-G-V-E-V-S-N-G-T-N-H-L-K-L-R-Y-Q-G-K-R-S-I-M-P-R-H-P-S-Q-E-I-K-E-P-L-R-K-A-I-I-K-Q-L-G-L"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-I-K-T-R-L-A-R-G-G-F-S-H-R-F-I-I-K-N-M-R-Y-P-V-T-L-E-P-V-E-E-G-G-Y-F-V-S-F-P-D-I-P-E-A-L-T-Q-G-D-T-R-E-E-A-L-E-M-A-L-D-A-L-I-T-A-F-E-F-Y-F-E-D-N-E-K-I-P-L-P-G-P-V-G-Q-D-Y-V-D-V-P-L-S-V-A-S-K-V-L-M-L-N-A-F-L-D-S-K-L-T-Q-I-E-L-A-N-R-M-G-V-K-K-Q-E-V-T-R-I-F-D-L-R-H-S-T-K-I-D-T-V-G-K-V-A-S-A-I-G-H-Q-L-T-L-S-I-E"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-T-K-K-K-A-H-K-P-G-S-A-T-I-A-M-N-R-R-A-R-H-E-Y-F-I-E-E-E-F-E-A-G-L-S-L-Q-G-W-E-V-K-S-L-R-A-G-K-A-N-I-S-D-S-Y-V-L-L-K-D-G-D-A-Y-L-F-G-A-T-I-T-P-L-N-V-A-S-S-H-V-V-C-D-P-M-R-S-R-K-L-L-L-N-Q-R-E-L-D-S-L-Y-G-R-V-N-R-E-G-Y-T-V-V-A-L-S-L-Y-W-K-N-A-W-C-K-V-R-I-G-V-A-K-G-K-K-A-H-D-K-R-S-D-I-K-E-R-E-W-K-L-D-K-A-R-I-M-K-N-A-G-R"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-S-K-E-Q-K-M-P-D-E-Q-V-S-E-D-M-E-V-V-S-E-Q-Q-N-S-A-D-K-A-E-A-S-E-T-E-S-V-V-D-P-R-V-A-E-L-E-E-Q-L-K-Q-A-Q-Q-R-E-R-D-A-I-L-R-A-K-A-E-V-E-N-I-R-R-R-T-E-Q-D-V-E-K-A-H-K-F-A-L-E-R-F-A-N-E-L-L-P-V-I-D-N-L-E-R-A-L-E-V-A-D-R-T-N-T-E-I-A-P-M-V-E-G-I-E-L-T-L-K-S-F-L-G-A-V-G-K-F-G-I-E-V-V-G-D-T-N-V-P-F-N-P-E-I-H-Q-A-M-T-M-M-E-S-D-Q-H-E-P-N-H-V-M-M-V-M-Q-K-G-Y-T-L-N-G-R-L-L-R-P-A-M-V-A-V-S-K"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-I-G-L-G-T-D-I-V-E-I-A-R-I-E-G-V-V-E-R-S-G-E-R-L-A-K-R-I-L-S-E-L-E-W-E-Q-Y-Q-Q-H-E-K-P-V-R-F-L-A-K-R-F-A-V-K-E-A-A-A-K-A-L-G-T-G-I-R-N-G-L-A-F-N-Q-F-E-V-V-N-D-A-L-G-K-P-I-L-R-L-Y-G-A-A-A-A-L-A-Q-Q-L-G-A-T-S-L-H-V-T-L-A-D-E-R-R-Y-A-C-A-T-V-I-L-E-R"} +{"text": "### FUNCTION Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins ### SEQUENCE -M-R-L-T-S-K-G-R-Y-A-V-T-A-M-L-D-V-A-L-H-S-Q-E-G-P-V-P-L-A-D-I-S-E-R-Q-G-I-S-L-S-Y-L-E-Q-L-F-S-R-L-R-K-N-G-L-V-S-S-V-R-G-P-G-G-G-Y-L-L-G-K-D-A-S-E-I-V-V-A-E-V-I-F-A-V-D-E-S-V-D-A-T-R-C-Q-G-R-E-G-C-Q-G-G-D-R-C-L-T-H-A-L-W-R-D-L-S-D-R-I-T-G-F-L-S-S-I-S-L-E-E-L-V-N-N-Q-E-V-L-D-V-A-G-R-Q-D-N-D-K-R-R-A-P-N-G-R-A-Q-E-T-I-N-V-N-L-R-P"} +{"text": "### FUNCTION Is able to transfer iron-sulfur clusters to apo-ferredoxin Multiple cycles of cluster formation and transfer are observed, suggesting that IscA acts catalytically Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB ### SEQUENCE -M-S-I-S-L-T-E-S-A-A-Q-R-V-S-S-F-L-S-H-R-G-K-G-V-G-L-R-L-G-V-R-T-S-G-C-S-G-M-A-Y-L-L-E-F-A-D-M-I-N-E-D-D-T-V-F-E-D-K-G-V-K-V-I-V-D-G-K-S-M-V-Y-L-D-G-T-E-L-D-F-V-K-E-G-L-N-E-G-F-K-F-N-N-P-N-V-S-S-E-C-G-C-G-E-S-F-N-V"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-D-Y-F-T-L-F-G-L-P-A-R-Y-T-V-D-R-E-Q-L-A-S-C-Y-Q-E-L-Q-R-Q-F-H-P-D-R-F-A-S-Q-P-E-R-E-K-T-L-A-L-Q-Q-A-V-T-I-N-D-G-Y-Q-T-L-K-H-P-L-K-R-A-E-Y-M-L-S-L-H-G-F-D-L-A-N-E-Q-H-T-M-N-D-N-A-F-L-M-E-Q-L-M-L-R-E-E-L-E-C-I-A-D-K-A-N-P-E-V-A-L-A-D-F-A-A-R-L-N-G-M-I-K-T-R-S-Q-L-M-V-Q-Q-L-D-E-Q-Q-W-E-Q-A-A-D-T-V-R-K-L-R-F-L-D-K-L-Q-Q-Q-V-E-Q-L-E-E-R-L-L-D-D-F"} +{"text": "### FUNCTION Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle Catalyzes the conversion of ### SEQUENCE -M-H-V-T-L-V-E-I-N-V-K-Q-D-K-L-D-E-F-I-E-V-F-R-L-N-H-L-G-S-I-K-E-A-G-N-L-R-F-D-V-L-R-D-E-N-I-P-T-R-F-Y-I-Y-E-A-Y-V-D-E-N-A-A-N-T-H-K-Q-T-S-H-Y-L-K-C-V-E-Q-L-E-S-L-I-S-E-P-R-K-K-R-S-F-I-G-V-M-P-E-I-K"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-F-T-I-N-A-E-V-R-K-E-Q-G-K-G-A-S-R-R-L-R-R-A-N-K-F-P-A-I-V-Y-G-G-N-Q-E-L-V-S-I-E-L-D-H-D-Q-V-I-N-M-E-Q-K-A-E-F-Y-S-D-V-L-T-L-V-I-D-G-K-E-T-K-V-K-V-Q-A-V-Q-R-H-P-F-K-P-K-L-A-H-I-D-F-L-R-A"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-T-Q-I-I-L-A-S-T-S-A-Y-R-R-M-L-L-E-K-L-R-L-P-F-I-C-A-A-P-N-T-D-E-T-P-R-M-N-E-N-A-E-Q-L-V-M-R-L-A-Q-A-K-A-Q-A-L-Q-T-K-Y-S-Q-H-L-I-I-G-S-D-Q-V-C-V-I-N-G-E-I-T-G-K-P-H-S-F-E-H-A-F-K-Q-L-R-Q-A-S-G-H-C-V-T-F-Y-T-G-I-S-L-F-N-S-K-T-G-I-T-D-T-R-C-E-L-F-N-V-Y-F-R-E-L-A-D-D-E-I-R-A-Y-L-T-A-E-N-P-L-N-C-A-G-S-F-K-S-E-G-L-G-I-T-L-F-E-R-L-E-G-K-D-P-N-T-L-I-G-L-P-L-I-T-L-T-E-L-L-I-R-Q-G-V-N-P-L-T-A-I-G"} +{"text": "### FUNCTION Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B ### SEQUENCE -M-R-R-I-L-F-V-A-L-S-V-M-F-L-A-G-C-P-S-L-P-P-E-Q-P-E-P-P-T-P-V-V-P-V-T-P-S-E-K-P-T-P-P-S-E-K-V-P-E-P-P-K-M-S-A-I-D-W-E-S-T-V-Q-P-L-V-E-Q-L-V-K-A-H-G-L-E-N-A-K-L-L-L-V-D-T-V-K-N-N-T-N-G-A-L-Q-T-M-Q-A-T-D-A-L-R-Q-A-I-S-S-E-H-V-F-E-L-I-P-Q-N-Q-V-Q-N-A-R-Q-S-L-G-L-S-E-E-D-S-L-G-L-R-S-K-A-I-G-L-A-R-Y-L-N-A-E-Y-V-L-Y-S-I-V-S-G-N-S-D-K-R-D-I-V-M-Q-L-M-L-V-K-T-G-E-I-L-W-S-G-H-G-D-V-K"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-N-M-Y-A-T-L-I-L-A-L-A-L-S-M-D-A-F-A-A-S-I-C-K-G-A-A-L-H-R-P-H-F-R-E-A-I-R-T-G-L-I-F-G-L-A-E-A-C-T-P-L-I-G-W-S-L-G-L-Y-A-S-Q-Y-I-I-E-W-D-H-W-V-A-F-T-L-L-F-I-L-G-C-R-M-I-T-E-S-F-K-T-K-Q-E-K-K-C-E-S-P-C-R-H-N-S-I-V-L-I-T-T-A-I-A-T-S-L-D-A-M-A-I-G-I-G-L-A-F-L-E-V-N-I-V-H-T-A-M-A-I-G-M-M-T-M-I-M-A-T-L-G-M-L-I-G-R-Y-I-G-P-R-L-G-K-R-A-E-L-I-G-G-L-I-L-I-A-I-G-F-N-I-L-F-E-H-L-E-L-F-M-Y-A-K"} +{"text": "### FUNCTION Probably mediates the hydrolysis of some nucleoside diphosphate derivatives ### SEQUENCE -M-I-S-L-S-D-F-V-N-R-F-Q-L-Q-L-P-P-P-P-K-R-L-S-D-N-N-R-H-A-A-V-L-L-P-I-I-C-K-P-K-P-T-L-L-L-T-R-R-S-A-T-L-R-S-H-A-G-Q-V-A-F-P-G-G-V-A-D-P-K-D-K-S-I-I-A-T-A-L-R-E-A-E-E-E-V-N-I-P-H-Q-K-V-Q-V-L-G-Q-L-A-P-L-N-S-S-G-G-Y-L-V-T-P-I-V-G-L-L-P-P-G-L-S-L-H-S-N-P-A-E-V-A-K-I-F-E-V-P-L-S-E-A-L-S-L-S-S-Y-H-Y-L-D-V-S-R-R-G-Q-Q-H-R-V-Y-F-Y-W-Y-Q-Q-H-L-I-W-G-L-T-A-T-I-I-H-Q-L-A-Q-Q-V-Q-V"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-V-A-R-A-R-H-K-K-I-L-K-Q-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-A-R-Q-N-G-L-S-Y-S-R-F-I-D-G-L-K-K-A-S-I-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-V-A-F-A-A-L-V-E-K-A-K-S-A-L-A"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-E-M-S-E-N-L-F-E-K-L-G-I-S-K-R-D-A-K-D-L-V-E-L-F-F-E-E-V-R-R-S-L-E-N-G-E-Q-V-K-L-S-G-F-G-N-F-D-L-R-D-K-N-Q-R-P-G-R-N-P-K-T-G-E-D-I-P-I-T-A-R-R-V-V-T-F-R-P-G-Q-K-L-K-S-R-V-E-K-A-T-P-K-E"} +{"text": "### FUNCTION Participates in cysteine desulfuration mediated by SufS Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process ### SEQUENCE -M-A-S-L-P-D-T-N-K-L-L-R-N-F-S-R-C-R-N-W-E-E-R-Y-L-Y-M-I-E-L-G-A-K-L-P-P-L-T-D-E-Q-R-Q-P-E-N-L-I-A-G-C-Q-S-Q-V-W-I-L-L-R-M-N-H-Q-N-K-V-E-F-I-G-D-S-D-A-A-I-V-K-G-L-V-A-I-V-F-I-L-F-Q-G-K-T-T-Q-E-I-L-D-L-D-V-T-E-Y-F-G-K-L-S-L-E-Q-H-L-T-P-S-R-T-Q-G-L-H-A-M-I-H-A-I-R-N-R-T-S-K-M-V"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-M-R-F-L-N-H-C-S-Q-G-R-S-A-W-L-L-M-I-L-T-A-L-I-L-E-S-S-A-L-Y-F-Q-H-V-M-K-L-Q-P-C-V-M-C-I-Y-E-R-V-A-L-F-G-V-L-S-A-G-I-L-G-V-I-A-P-K-T-P-L-R-W-L-A-I-I-L-W-I-Y-S-A-W-G-G-L-Q-L-A-W-Q-H-T-M-M-Q-L-H-P-S-P-F-N-T-C-D-F-F-V-N-F-P-S-W-L-A-L-N-Q-W-L-P-S-V-F-E-A-T-G-D-C-S-V-R-Q-W-Q-F-L-T-L-E-M-P-Q-W-L-V-G-I-F-A-A-Y-L-V-V-A-A-L-V-L-I-S-Q-F-F-S-R-K"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-Q-L-L-D-F-L-P-L-V-V-F-F-V-V-Y-K-M-Y-D-I-F-Y-A-S-G-A-L-I-A-A-T-G-L-A-V-A-M-T-Y-F-I-Y-R-K-V-E-K-A-S-L-I-T-F-I-M-V-A-V-F-G-T-L-T-L-A-F-H-S-D-L-F-I-K-W-K-V-T-V-I-Y-A-L-F-A-L-A-L-L-G-S-Q-W-F-M-K-K-P-L-I-Q-K-M-L-G-K-E-L-I-L-P-D-L-V-W-N-K-L-N-M-A-W-A-L-F-F-T-A-C-A-L-A-N-I-Y-V-A-F-W-L-P-Q-D-V-W-V-N-F-K-V-F-G-L-T-A-L-T-L-V-F-T-V-L-S-V-V-Y-I-Y-R-H-L-P-R-E-Q-K"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-T-D-Y-F-L-L-F-V-G-T-V-L-V-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-L-E-T-A-I-G-M-G-F-A-T-T-F-V-M-T-L-A-S-V-C-S-W-L-V-N-T-F-I-L-L-P-L-D-L-I-Y-L-R-T-L-S-F-I-L-V-I-A-V-V-V-Q-F-T-E-L-V-V-R-K-T-S-P-T-L-Y-R-L-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-I-N-Q-S-H-D-F-L-Q-S-A-I-Y-G-F-G-A-A-A-G-F-S-L-V-M-V-L-F-A-A-I-R-E-R-L-A-V-A-D-V-P-A-P-F-K-G-S-S-I-G-L-I-T-A-G-L-M-S-L-A-F-M-G-F-S-G-L-V-K-F"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin depleting activity of cognate toxin Res ### SEQUENCE -M-R-V-F-T-P-S-H-K-V-Q-S-N-P-L-W-R-T-V-G-F-P-S-S-S-G-P-H-L-N-A-I-L-N-E-G-L-P-V-T-I-V-D-K-I-Q-N-W-S-T-F-G-K-G-D-I-L-R-I-A-G-I-Q-I-R-S-Y-S-R-R-C-S-G-K-G-K-F-T-A-D-E-S-Q-R-I-A-R-F-V-R-V-M-D-H-A-V-D-L-F-N-G-D-K-D-K-A-A-Q-W-M-K-R-P-I-R-G-L-G-Y-V-T-P-E-S-M-L-D-T-E-S-G-A-L-D-V-M-N-L-I-G-R-I-E-H-G-I-V-S"} +{"text": "### FUNCTION Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid , respectively This protein seems to be a 2Fe-2S ferredoxin ### SEQUENCE -M-S-Q-L-F-V-C-T-V-E-E-L-P-D-G-G-A-R-K-V-E-Y-T-P-D-I-A-L-F-H-Y-D-G-E-F-F-A-V-D-D-R-C-S-H-G-N-A-S-I-S-E-G-Y-L-E-D-N-A-T-V-E-C-P-L-H-T-A-S-F-C-L-R-T-G-K-A-L-C-L-P-A-T-D-P-L-K-T-Y-P-V-V-V-K-D-G-N-I-Y-I-T-V-S-E-E-Q"} +{"text": "### FUNCTION Part of the multicomponent 3-phenylpropionate dioxygenase Converts 3-phenylpropionic acid , respectively ### SEQUENCE -M-K-E-L-I-V-N-Q-E-K-R-V-S-P-E-L-H-Y-E-I-S-Q-F-L-Y-Y-E-I-A-L-L-D-E-W-R-F-R-D-W-L-E-L-L-S-E-D-L-S-Y-T-M-R-T-I-V-N-A-Q-T-R-D-R-R-K-S-I-Q-P-P-T-T-W-L-F-N-D-N-K-F-Q-L-E-R-R-I-A-R-L-E-T-G-M-A-W-A-E-E-P-P-S-R-T-R-H-L-L-T-N-L-V-I-T-E-T-D-L-P-D-Q-F-H-V-Q-S-N-Y-L-L-Y-R-S-Q-K-E-R-D-E-V-F-Y-V-G-K-R-L-D-C-V-R-R-N-P-K-T-D-S-W-L-I-C-K-R-E-I-T-L-D-Q-A-V-L-T-F-H-N-L-S-V-L-F"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-A-L-L-D-F-F-L-S-R-K-K-T-T-A-N-I-A-K-E-R-L-Q-I-I-V-A-E-R-R-R-G-D-S-E-P-A-Y-L-P-D-M-K-R-D-I-L-A-V-I-C-K-Y-I-Q-V-D-P-D-M-L-S-V-Q-F-E-Q-K-G-D-D-I-S-V-L-E-L-N-I-T-L-P-E-A-E-E-T-Q-K"} +{"text": "### FUNCTION Catalyzes the excretion of spermidine ### SEQUENCE -M-Q-Q-F-E-W-W-H-A-A-F-L-F-L-A-V-V-L-D-I-L-A-N-I-L-L-K-L-S-N-G-F-R-R-P-W-M-G-I-L-S-L-I-A-V-L-G-A-F-S-A-L-A-Q-A-V-K-G-I-E-L-S-I-A-Y-A-L-W-G-A-F-G-I-I-A-T-V-A-A-G-W-I-M-F-N-Q-R-L-N-Y-K-G-W-G-G-I-A-L-L-L-L-G-M-V-M-I-K-M-A"} +{"text": "### FUNCTION Catalyzes the excretion of spermidine ### SEQUENCE -M-I-Y-W-L-F-L-A-M-A-I-I-T-E-V-I-G-T-L-S-M-K-H-A-S-V-S-G-G-V-V-G-M-A-V-M-Y-I-M-I-A-T-S-Y-I-L-L-A-M-A-V-K-K-V-A-L-G-V-A-Y-A-L-W-E-G-V-G-I-L-F-I-T-V-F-S-V-M-W-F-D-E-S-L-S-L-M-K-V-G-G-L-A-L-L-I-T-G-I-M-L-I-K-S-G-T-R-K-A-A-V-K-K-S-A-E-V-V-K-Q-M-A-N-K-A-V-S-V-A-T-T-K-S-S-K-I-K-E-A"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-N-I-K-L-I-V-G-L-A-N-P-G-A-E-Y-A-Q-T-R-H-N-A-G-A-W-Y-V-D-L-L-A-R-S-H-N-Q-S-L-K-E-E-S-K-F-F-G-Y-T-A-R-I-N-I-C-G-H-D-V-R-L-L-V-P-T-T-F-M-N-L-S-G-K-S-V-V-A-L-A-S-F-Y-R-I-Q-P-D-E-I-L-V-A-H-D-E-L-D-L-P-P-G-V-A-K-M-K-L-G-G-S-H-G-G-H-N-G-L-K-D-I-Q-N-K-F-G-N-N-P-N-F-Y-R-L-R-I-G-I-G-H-P-G-D-K-N-K-V-V-G-F-V-L-G-K-P-P-A-S-E-Q-Q-L-I-D-D-A-I-D-E-A-R-R-C-T-D-I-L-M-K-Q-D-M-D-K-A-I-N-R-L-H-S-F-K-A-S-V"} +{"text": "### FUNCTION Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD As a transcriptional regulator, acts as an anti-FlhDC factor ### SEQUENCE -M-D-N-K-M-D-L-L-S-A-Y-Q-R-I-L-S-L-S-E-Q-M-L-N-L-A-K-N-E-K-W-D-E-L-V-D-M-E-I-T-Y-L-K-A-V-E-V-I-S-H-S-S-I-S-S-T-T-S-L-S-L-Q-Q-K-M-T-N-I-L-Q-I-I-L-D-N-E-N-E-I-K-K-L-L-Q-K-R-L-D-E-L-S-K-L-I-K-Q-A-S-Q-Q-Q-L-L-N-D-S-Y-G-Q-F-P-V-E-P-Y-H-N-T-L-M-N-S-T-E-Q-K"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine ### SEQUENCE -M-I-M-L-V-F-E-G-Q-E-I-E-T-D-A-Q-G-Y-L-K-N-S-S-D-W-E-E-A-I-A-L-L-L-A-K-Q-E-E-I-T-L-T-E-P-H-W-E-V-I-R-F-I-R-E-F-Y-K-E-F-N-T-S-P-A-I-R-M-L-V-K-A-I-A-Q-K-Y-G-E-E-K-G-N-S-R-Y-L-Y-R-L-F-P-K-G-P-A-K-Q-A-T-K-I-A-G-L-P-K-P-V-K-C-I"} +{"text": "### FUNCTION Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress ### SEQUENCE -M-I-I-A-S-K-F-G-I-G-Q-Q-V-R-H-K-L-L-G-Y-L-G-V-I-V-D-I-D-V-E-Y-S-L-E-Q-P-Q-E-D-D-I-A-S-N-A-T-L-R-S-A-P-W-Y-H-V-V-M-E-D-D-N-G-Q-P-V-H-T-Y-L-A-E-A-Q-L-A-Y-E-T-S-D-E-H-P-E-Q-P-S-L-D-E-L-A-E-S-I-R-H-Q-L-L-A-P-R-L-R-N"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-E-L-T-T-R-T-M-A-T-A-K-N-I-A-L-I-A-H-D-H-C-K-T-S-L-L-A-W-S-K-K-H-K-S-L-L-K-K-H-H-L-Y-A-T-G-T-T-G-N-L-I-Q-N-E-T-G-L-S-V-T-N-M-L-S-G-P-M-G-G-D-Q-Q-I-G-S-L-I-S-E-G-K-I-D-V-L-I-F-F-W-D-P-L-N-S-V-P-H-D-P-D-V-K-A-L-L-R-L-A-T-V-W-N-I-P-V-A-T-N-L-A-S-A-D-F-I-V-S-S-P-L-F-S-E-S-V-D-I-Q-V-P-D-Y-Q-H-Y-L-N-G-R-L-K"} +{"text": "### FUNCTION Component of the SOS system and an inhibitor of cell division Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments In the presence of GTP, binds a polymerization-competent form of FtsZ in a 11 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division ### SEQUENCE -M-G-I-Q-S-S-W-F-Y-S-S-K-H-Q-S-A-K-R-E-G-M-V-K-E-G-K-G-G-I-V-S-E-L-I-Y-S-N-N-Q-Y-S-D-N-Q-Y-S-D-N-Q-A-V-I-N-R-I-L-L-P-L-L-R-Q-S-G-N-E-A-R-W-L-L-W-V-S-P-H-K-K-L-S-R-Q-W-L-I-N-S-G-L-P-L-D-K-I-I-Q-L-N-R-M-S-S-I-T-T-V-E-A-M-E-R-A-L-A-S-G-N-Y-S-V-V-L-G-W-L-P-T-L-S-G-K-D-T-V-R-L-Q-A-A-A-Q-K-G-N-A-L-G-F-I-M-R-P-Q-D-V-S-K-E-T-S-R-A-E-S-R-S-D-L-L-K-I-H-S-I-H-Y-H"} +{"text": "### FUNCTION Required for spatial organization of the terminus region of the chromosome during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-Q-L-E-N-L-E-C-G-W-K-W-T-Y-L-M-K-K-H-Q-E-G-E-L-I-T-K-Y-I-E-N-S-A-A-H-A-A-V-D-K-L-I-E-L-E-S-E-P-V-R-V-L-K-W-I-E-Q-H-M-N-P-D-L-S-N-R-M-K-Q-T-I-R-A-R-R-K-R-H-F-N-A-E-H-Q-H-T-R-K-K-S-I-D-L-D-F-P-V-W-H-R-L-S-A-L-S-Q-R-R-G-N-T-L-S-E-T-I-I-Q-L-I-E-D-A-E-R-K-E-K-Y-A-N-Q-M-S-S-L-K-H-D-L-E-A-I-L-G-K-K-E"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-R-L-A-G-Q-Q-S-H-I-S-A-K-T-V-E-D-A-V-K-E-I-L-D-H-M-A-I-T-L-A-D-G-E-R-I-E-V-R-G-F-G-S-F-S-L-H-Y-R-A-P-R-V-G-R-N-P-K-T-G-D-K-V-E-L-E-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-D-R-V-N-I-Y-D"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-N-E-Y-H-N-S-L-K-S-K-E-S-V-K-D-E-R-Q-Q-K-L-Q-P-P-S-M-Y-Q-V-I-L-N-N-D-D-Y-T-P-M-E-F-V-V-D-V-L-R-K-F-F-S-Y-D-I-E-R-A-T-Q-L-M-L-D-V-H-Y-Q-G-K-A-V-C-G-V-Y-T-A-E-V-A-E-T-K-A-A-Q-V-N-M-Y-A-K-E-Y-G-H-P-L-L-C-T-L-E-K-V"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-I-W-L-R-S-S-V-V-L-L-I-F-L-T-L-I-T-G-V-A-Y-P-L-L-A-T-G-L-S-E-L-M-F-P-Y-Q-A-Q-G-S-M-V-K-Q-D-G-Q-T-V-G-S-E-L-I-G-Q-P-F-T-K-A-I-Y-F-Q-G-R-P-S-A-T-V-D-Y-P-Y-N-T-L-S-S-G-G-S-N-L-A-T-T-N-P-I-L-D-D-E-I-K-R-R-V-E-Q-L-R-Q-F-N-R-Q-P-D-I-P-V-P-V-D-L-V-T-A-S-A-S-G-L-D-P-H-I-S-P-A-A-A-D-F-Q-A-Q-R-V-A-D-A-R-H-L-P-I-K-V-I-K-Q-L-I-R-D-N-I-E-H-P-P-S-E-F-L-G-E-P-V-I-N-V-L-K-L-N-L-A-L-D-N-L-P-E-K-K-Q"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-S-V-I-L-D-L-Q-I-A-C-E-H-S-Q-G-L-P-K-E-T-L-F-Q-H-W-L-D-G-V-L-P-Q-F-Q-S-E-S-E-V-T-I-R-I-V-D-E-A-E-S-H-D-L-N-L-T-Y-R-G-K-N-K-P-T-N-V-L-S-F-P-F-E-A-P-P-E-I-D-L-P-L-L-G-D-L-I-I-C-R-Q-V-V-E-K-E-A-E-E-Q-Q-K-T-I-E-E-H-W-A-H-M-V-V-H-G-C-L-H-L-L-G-Y-D-H-I-E-D-D-E-A-E-E-M-E-S-L-E-T-E-I-M-Q-K-L-G-Y-A-D-P-Y-L-A-E-K-E"} +{"text": "### FUNCTION Together with LptD, is involved in the assembly of lipopolysaccharide at the surface of the outer membrane Required for the proper assembly of LptD Binds LPS and may serve as the LPS recognition site at the outer membrane ### SEQUENCE -M-R-H-R-I-L-T-L-L-L-G-L-A-V-L-V-T-A-G-C-G-F-H-L-R-G-T-T-Q-V-P-A-E-L-K-K-L-Q-I-T-S-S-D-P-Y-G-P-L-A-R-S-V-R-Q-Q-L-R-L-N-N-V-T-I-L-E-D-G-S-A-D-V-P-V-L-K-L-I-D-S-S-E-N-K-D-T-V-S-V-F-Q-D-G-K-A-A-E-R-Q-L-T-L-N-V-N-A-Q-V-I-M-P-D-G-S-V-Y-P-L-R-S-R-V-D-R-S-F-F-D-N-P-L-E-A-L-A-K-D-A-E-N-E-I-I-N-Q-E-M-R-E-Q-A-A-R-R-L-V-R-Q-L-L-T-V-H-N-A-E-K-Q-K-A-R-E-K-Q-V-G-Q-Q-A-A-Q-A-Q"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-L-Q-L-I-A-V-G-T-K-M-P-D-W-I-Q-A-G-F-T-D-Y-L-R-R-F-P-K-D-M-P-F-D-L-I-E-I-P-A-G-K-R-G-K-N-A-D-I-K-R-I-L-E-K-E-G-E-Q-M-L-A-A-V-S-K-G-S-R-I-V-T-L-D-I-P-G-S-R-W-E-T-P-Q-L-A-Q-Q-L-E-H-W-K-R-D-G-R-D-V-S-L-L-I-G-G-P-E-G-L-A-P-A-C-K-A-A-A-E-Q-S-W-S-L-S-P-L-T-L-P-H-P-L-V-R-V-L-V-A-E-S-L-Y-R-A-W-S-I-T-T-N-H-P-Y-H-R-E"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-N-I-I-L-A-I-F-I-G-G-G-L-G-S-V-L-R-W-F-I-S-L-R-L-N-N-I-S-S-N-I-A-I-G-T-L-T-V-N-C-I-G-A-L-I-I-G-L-G-L-A-Y-F-N-K-S-T-H-L-D-P-A-W-K-L-M-L-T-T-G-F-C-G-G-L-T-T-F-S-T-F-S-V-E-V-V-Y-L-L-L-D-G-K-L-G-W-A-L-G-T-V-L-L-N-L-F-G-S-L-L-M-T-M-L-A-F-V-L-M-H-E-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-N-I-I-K-Q-L-E-Q-E-Q-M-K-Q-D-V-P-S-F-R-P-G-D-S-V-E-V-K-V-W-V-V-E-G-A-K-K-R-L-Q-A-F-E-G-V-V-I-A-I-R-N-R-G-L-H-S-A-F-T-V-R-K-V-S-N-G-E-G-V-E-R-V-F-Q-T-H-S-P-V-V-D-S-I-N-V-K-R-R-G-A-V-R-R-A-K-L-Y-Y-L-R-E-R-S-G-K-A-A-R-I-K-E-R-L-N-S-K"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-V-T-M-S-K-Q-T-C-I-E-L-P-V-N-P-I-V-L-G-K-L-G-S-T-Y-G-I-R-G-W-L-R-V-F-S-S-T-E-H-A-E-D-I-F-A-Y-Q-P-W-F-I-Q-R-A-G-R-W-Q-H-I-E-L-E-A-W-K-H-H-N-Q-D-M-I-I-K-I-K-G-I-D-D-L-D-A-A-N-S-L-T-N-C-E-I-I-V-D-S-E-Q-L-P-E-L-D-T-G-D-Y-Y-W-K-D-L-I-G-C-Q-V-I-S-T-A-G-Y-N-L-G-T-V-N-D-M-M-E-T-G-S-N-D-V-M-V-V-K-A-N-L-K-D-A-F-G-V-K-E-R-L-I-P-F-L-D-G-Q-V-I-K-K-V-D-L-A-T-K-T-I-E-V-D-W-D-P-G-F"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-N-N-R-T-I-M-A-F-D-F-G-T-R-S-I-G-A-A-I-G-Q-E-I-T-G-T-A-R-A-L-T-S-F-K-A-T-D-G-I-P-N-W-G-Q-I-E-K-L-L-K-E-W-Q-P-D-L-V-I-V-G-L-P-L-N-M-D-G-T-E-Q-F-V-T-V-Q-A-R-K-F-A-N-R-L-H-G-R-F-G-V-Q-V-Q-L-Q-D-E-R-L-T-T-V-E-A-R-A-H-L-F-D-R-G-G-Y-K-A-L-N-K-G-K-V-D-A-T-S-A-V-I-I-L-E-S-W-F-E-Q-R-Y"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-M-S-D-D-I-V-L-P-L-Q-F-T-D-A-A-A-N-K-V-K-I-L-V-S-D-E-E-N-P-N-L-R-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-D-Q-I-N-E-G-D-M-T-I-E-K-Q-G-V-E-L-V-V-D-P-M-S-L-Q-Y-L-V-G-G-C-V-D-Y-T-E-G-L-E-G-S-R-F-I-V-T-N-P-N-A-K-T-T-C-G-C-G-S-S-F-S-I"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-G-K-L-T-L-L-L-L-V-L-L-G-W-L-Q-Y-S-L-W-L-G-K-N-G-I-H-D-Y-V-R-V-K-N-D-V-A-M-Q-E-R-N-N-S-K-L-K-A-R-N-D-Q-L-S-A-E-I-D-D-L-T-G-G-Q-E-A-I-E-E-R-S-R-S-E-L-G-M-I-K-P-G-E-T-F-Y-R-L-I-I-D-K-S-K-E-N-T-S-R-P-S-T-P-N-N-T-Q"} +{"text": "### FUNCTION Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm ### SEQUENCE -M-K-K-L-L-C-A-A-S-F-G-I-A-L-A-F-S-V-G-A-Q-A-A-D-K-I-A-V-V-N-V-G-E-I-F-Q-Q-L-P-A-R-E-A-V-V-K-Q-L-E-N-E-F-K-N-R-A-S-E-L-Q-R-M-E-T-D-L-Q-S-K-I-Q-K-L-Q-R-D-G-S-T-M-K-S-S-E-R-T-N-L-E-K-E-V-M-A-K-R-E-E-F-A-K-K-A-Q-A-F-E-Q-D-H-R-R-R-E-M-E-E-R-N-K-I-L-S-R-I-Q-D-A-I-K-V-V-A-G-K-E-G-Y-D-V-V-I-D-A-N-A-V-A-Y-S-V-S-G-K-N-I-T-T-S-V-L-K-Q-V-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-E-I-K-K-D-A-Q-D-R-M-E-K-S-V-E-A-L-K-N-Q-I-S-K-V-R-T-G-R-A-S-P-S-L-L-D-G-I-I-V-E-Y-Y-G-A-P-T-P-L-R-Q-L-A-N-V-I-A-E-D-A-R-T-L-A-I-T-V-F-D-R-T-M-T-P-A-I-E-K-A-I-M-A-S-D-L-G-L-N-P-S-S-A-G-T-T-I-R-V-P-L-P-P-L-T-E-E-R-R-K-D-L-I-K-V-V-R-S-E-A-E-Q-G-R-V-S-V-R-N-I-R-R-D-A-N-D-K-I-K-A-L-L-K-D-K-E-I-S-E-D-D-E-R-R-A-Q-D-D-I-Q-K-L-T-D-N-F-I-K-K-V-D-E-A-L-T-K-K-E-E-E-L-M-E-F"} +{"text": "### FUNCTION Inhibitor of the alkaline protease ### SEQUENCE -M-V-F-A-A-W-Y-L-K-F-A-G-F-V-A-L-I-F-S-I-I-G-G-S-M-A-S-S-L-V-L-P-H-A-S-E-L-K-G-V-W-Q-L-S-D-K-H-Q-Q-C-D-V-L-L-T-D-H-P-L-P-E-G-S-I-W-S-L-N-G-D-N-D-C-L-A-Y-M-F-G-E-V-P-A-G-W-R-P-T-P-D-G-L-T-I-T-D-E-Q-G-S-G-L-A-F-F-A-H-E-P-D-G-W-F-A-R-F-A-D-G-R-E-L-M-I-K-P-N-K-T-S-K-K-N-E"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-D-D-G-Y-R-P-N-V-G-I-V-I-C-N-R-Q-G-Q-V-L-W-A-R-R-Y-G-Q-H-S-W-Q-F-P-Q-G-G-I-N-P-G-E-S-P-E-Q-A-M-Y-R-E-L-Y-E-E-V-G-L-G-R-K-D-V-R-I-L-A-S-T-R-N-W-L-R-Y-K-L-P-K-R-L-V-R-W-D-T-R-P-V-C-I-G-Q-K-Q-R-W-F-L-L-Q-L-L-C-N-E-E-D-I-N-V-Q-H-S-N-T-P-E-F-D-G-W-R-W-V-S-Y-W-Y-P-V-R-Q-V-V-S-F-K-R-D-V-Y-R-R-V-M-K-E-F-A-S-V-V-M-P-M-Q-E-S-V-S-L-P-R-S-S-Y-S-Y-R-R-K-R-S"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-R-A-I-Q-S-E-K-R-R-K-H-N-A-S-R-R-S-M-V-R-T-F-I-K-K-V-Y-A-A-I-A-T-G-D-K-E-A-A-Q-K-A-F-H-D-M-Q-P-I-V-D-R-H-A-C-K-G-L-I-H-K-N-K-A-A-R-H-K-S-N-L-T-A-Q-I-N-A-M-Q"} +{"text": "### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription The complex also regulates trp repressor biosynthesis by binding to its regulatory region ### SEQUENCE -M-T-T-N-H-L-T-D-P-A-L-S-P-Q-D-H-E-D-W-Q-C-F-V-T-L-L-Q-Q-A-F-A-E-N-L-Q-H-P-I-L-Q-L-L-L-T-P-D-E-R-T-A-L-A-T-R-V-R-I-I-K-E-L-M-S-G-K-M-S-Q-R-E-L-K-N-E-L-G-V-G-I-A-T-I-T-R-G-S-N-S-L-K-F-A-S-N-D-V-K-A-W-L-E-Q-Q-L-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-I-N-K-E-Q-I-L-D-A-V-A-T-M-S-V-M-D-V-V-E-L-I-T-A-M-E-D-K-F-G-V-S-A-A-A-A-V-A-V-A-A-G-G-A-A-E-A-V-E-E-Q-T-E-F-D-V-V-L-S-A-I-G-G-N-K-V-A-V-I-K-A-V-R-G-A-T-G-L-G-L-K-E-A-K-D-L-V-E-S-A-P-N-A-T-L-K-E-G-I-S-K-D-D-A-E-A-L-K-K-S-L-E-E-A-G-A-S-V-E-I-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-Q-D-K-Q-A-I-V-A-E-V-S-E-V-A-K-G-A-L-S-A-V-V-A-D-S-R-G-V-T-V-D-K-M-T-E-L-R-K-A-G-R-E-A-G-V-Y-I-R-V-V-R-N-T-L-I-R-R-A-V-E-G-T-A-Y-E-C-L-K-E-A-F-V-G-P-T-L-I-A-F-S-N-E-H-P-G-A-A-A-R-L-F-K-E-F-A-K-A-N-P-A-F-E-I-K-A-A-A-F-E-G-E-F-I-P-A-A-N-I-D-R-L-A-T-L-P-T-Y-E-E-A-I-A-R-L-M-S-T-M-K-E-A-V-A-G-K-L-V-R-T-L-A-A-L-R-E-L-R-E-Q-K-E-V-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-I-G-Q-R-K-I-L-P-D-P-K-F-G-S-E-L-L-A-K-F-V-N-I-L-M-V-D-G-K-K-S-T-A-E-A-I-V-Y-S-A-L-E-T-L-A-Q-R-S-G-K-E-H-L-E-A-F-E-L-A-L-D-N-V-R-P-T-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-P-V-R-R-N-A-L-A-M-R-W-I-V-E-A-A-R-K-R-G-D-K-S-M-A-L-R-L-A-N-E-L-S-D-A-A-E-N-K-G-T-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-N-Q-L-V-R-K-P-R-S-M-K-V-A-K-S-N-V-P-A-L-E-A-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-Y-E-V-S-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-I-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-A-L-D-C-S-G-V-K-D-R-K-Q-G-R-S-K-Y-G-V-K-K-P-K-A"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-L-Y-T-V-G-R-S-P-Y-Q-C-D-F-N-V-I-S-K-L-L-A-R-G-D-D-I-L-F-I-Q-D-G-V-L-A-G-I-E-G-N-C-Y-L-S-A-L-I-S-C-G-A-A-L-Y-A-L-K-E-D-I-E-A-R-G-L-D-D-Q-V-S-D-K-V-Q-V-I-D-Y-T-D-F-V-N-L-T-V-K-H-H-Q-Q-F-A-W"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-K-K-I-A-F-I-F-T-K-T-P-H-G-D-A-G-G-R-E-G-L-D-A-L-L-A-T-S-A-L-T-E-K-V-G-V-F-F-I-S-D-G-V-L-Q-L-L-P-N-Q-Q-P-D-R-I-L-A-R-N-Y-I-A-T-F-K-V-L-P-L-Y-D-I-E-E-C-Y-L-C-Q-E-D-L-V-M-R-G-L-S-S-V-N-H-F-V-L-D-A-K-V-I-P-A-E-T-I-R-E-K-L-V-D-Y-D-V-V-L-T-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-S-S-L-S-Y-C-L-L-V-T-G-P-A-Y-G-T-Q-Q-A-S-S-A-Y-Q-F-A-Q-A-L-I-T-M-G-H-K-L-N-T-V-F-F-Y-R-E-G-V-Y-N-G-N-Q-L-T-S-P-A-S-D-E-F-D-L-V-S-A-W-Q-M-M-A-T-E-H-R-F-S-M-H-I-C-I-A-A-A-L-R-R-G-V-I-D-A-Q-Q-A-S-E-L-N-L-P-V-A-N-L-A-E-G-F-E-L-S-G-L-G-T-L-A-E-A-M-L-I-C-D-R-V-V-Q-F"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-D-A-V-E-K-I-G-N-R-F-D-L-V-L-V-A-A-R-R-A-R-Q-L-Q-T-G-G-K-D-P-L-V-A-E-E-N-D-K-V-T-V-I-A-L-R-E-V-E-E-G-L-I-N-G-K-I-L-D-V-R-E-R-Q-E-Q-Q-E-Q-E-A-A-E-M-Q-A-V-S-A-I-A-E-S-R-R"} +{"text": "### FUNCTION A GTPase-activating protein that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-N-P-L-K-K-K-A-P-A-K-V-S-A-S-K-Q-K-R-K-N-R-E-E-L-N-A-E-G-R-A-R-K-R-E-K-K-H-R-G-N-P-P-G-N-R-N-Q-E-Q-S-G-D-K-H-P-S-G-K-Q-Q-R-D-P-R-L-G-S-K-V-P-V-P-L-I-V-G-E-Q-P-T-K-P-V-V-A-N-K-V-E-T-K-P-R-L-S-P-Q-E-E-L-A-M-L-E-N-D-D-R-L-D-A-L-L-E-R-L-E-N-G-E-S-L-S-K-E-E-H-A-Y-V-D-T-T-L-D-R-I-D-A-L-M-E-E-L-G-I-K-L-D-E-E-E-R-E-E-E-K-Q-D-D-I-M-Q-L-L-K-G-N"} +{"text": "### FUNCTION May function as a transcriptional regulator that controls feoABC expression ### SEQUENCE -M-I-S-L-L-Q-V-R-D-A-V-A-L-N-G-R-A-D-A-K-L-L-S-H-Q-L-S-A-S-L-S-M-V-E-A-M-L-E-Q-L-T-V-M-G-K-L-E-K-L-N-A-T-A-C-L-S-G-S-C-K-Q-C-P-E-V-Q-Q-C-D-T-V-V-Y-R-I-A-G-G-Y"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-N-I-T-E-A-A-Q-T-H-F-A-K-L-L-A-N-Q-E-P-G-T-Q-I-R-V-F-V-I-N-P-G-T-P-T-A-E-C-G-V-S-Y-C-P-P-D-A-V-E-A-T-D-T-E-L-K-F-D-Q-L-S-A-Y-V-D-E-L-S-A-P-F-L-E-E-A-E-I-D-F-V-T-D-Q-L-G-S-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-S-D-D-S-P-L-A-E-R-V-E-Y-V-L-Q-S-Q-I-N-P-Q-L-A-G-H-G-G-R-V-S-L-M-E-I-T-D-D-G-F-A-I-L-Q-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-E-G-I-E-K-E-L-L-N-M-F-P-E-L-K-G-V-K-D-L-T-E-H-Q-R-G-E-H-S-Y-Y"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-E-H-F-Q-T-I-S-P-E-Q-A-Y-Q-H-W-Q-N-K-S-A-I-M-V-D-I-R-D-P-Q-S-F-R-T-G-H-A-C-G-A-F-H-L-T-N-D-T-L-N-E-L-M-L-Q-A-N-F-E-Q-P-V-M-V-M-C-Y-H-G-H-S-S-Q-S-A-A-Q-Y-L-L-N-I-G-F-E-T-V-Y-S-I-N-G-G-F-E-A-W-R-R-D-Y-P-H-A-V-D-S-L-H-N-P-A"} +{"text": "### FUNCTION Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide ### SEQUENCE -M-T-Q-S-Q-Y-S-Q-T-P-R-L-A-L-T-D-A-I-I-D-A-K-A-R-K-N-L-T-F-E-D-I-A-Q-G-T-G-L-S-L-A-F-V-T-A-A-L-L-G-Q-H-P-L-P-A-D-A-A-R-V-V-V-D-R-L-E-L-E-E-D-A-F-F-L-L-Q-T-I-P-V-R-G-S-I-P-G-G-I-P-T-D-P-T-I-Y-R-F-Y-E-M-V-Q-V-Y-G-S-T-L-K-A-L-V-H-E-Q-F-G-D-G-I-I-S-A-I-D-F-K-L-D-I-K-K-V-D-D-P-N-G-G-S-R-A-V-I-T-L-D-G-K-Y-L-P-T-K-P-F"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-I-N-A-T-I-L-G-Q-A-I-A-F-V-L-F-V-M-F-C-M-K-F-V-W-P-P-I-M-A-A-I-E-K-R-Q-K-E-I-A-D-G-L-S-S-A-E-R-A-K-K-D-L-D-L-A-Q-A-N-A-T-D-Q-M-K-K-A-K-V-E-A-Q-V-I-I-E-Q-A-N-K-Q-K-A-Q-I-L-D-D-A-K-A-E-A-E-Q-E-R-N-R-I-V-T-Q-A-Q-A-E-I-D-A-E-R-K-R-A-R-E-E-L-R-K-Q-V-A-M-L-A-I-A-G-A-E-K-I-I-E-R-S-V-D-E-A-A-N-S-D-I-V-D-K-L-V-A-E-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-E-F-A-T-V-A-R-P-Y-A-K-A-A-F-D-F-A-V-E-K-Q-S-L-E-Q-W-Q-N-M-L-A-F-T-A-E-V-T-R-N-E-Q-V-G-E-L-L-S-G-S-L-A-S-E-T-L-A-N-T-F-I-A-I-C-G-E-Q-V-D-E-H-A-Q-N-F-I-R-V-M-A-E-N-G-R-L-L-A-L-P-E-V-L-Q-Q-F-I-Q-L-R-A-S-L-E-S-T-V-D-V-E-V-I-S-A-T-E-L-R-E-Q-Q-L-A-K-I-S-V-A-M-E-K-R-L-S-R-K-V-K-L-N-C-K-I-D-K-S-V-I-A-G-V-V-V-R-A-G-D-L-V-I-D-G-S-I-R-G-R-L-D-R-L-T-D-V-L-Q-S"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-A-M-T-Y-H-L-N-V-V-S-A-E-S-R-M-F-E-G-L-V-Q-K-I-Q-V-T-G-S-E-G-E-L-G-I-Y-P-G-H-A-P-L-L-T-A-I-K-P-G-M-V-R-I-V-K-Q-F-G-E-E-E-V-I-Y-L-S-G-G-I-L-E-V-Q-P-S-G-V-I-V-L-A-D-T-A-I-R-G-K-D-L-D-E-A-K-A-L-E-S-K-R-K-A-E-E-H-I-R-N-S-H-G-D-V-D-Y-A-Q-A-S-A-E-L-S-K-A-I-A-K-L-R-V-I-E-L-T-K-K-A-M"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-K-S-K-L-K-P-T-N-D-W-L-V-T-D-D-N-P-K-M-R-E-V-C-T-E-V-K-F-P-L-S-Q-E-V-L-D-I-I-D-K-M-L-A-Y-V-D-E-S-F-D-D-N-A-E-K-Y-D-I-R-P-G-I-G-I-A-A-N-Q-L-G-L-N-Q-R-F-F-Y-V-H-F-T-D-F-C-Q-K-E-H-R-Y-L-L-I-N-P-E-W-I-D-K-S-L-N-K-A-Y-L-A-V-G-E-G-C-L-S-V-P-K-D-K-D-G-Y-V-I-R-S-E-T-V-K-L-K-G-F-D-Y-L-T-Q-K-D-V-E-I-S-A-H-G-L-L-A-M-C-L-Q-H-E-M-D-H-L-E-G-K-F-Y-Y-D-S-I-N-M-M-K-P-Y-F-K-K-D-E-W-V-S-I-D-Q-K-V-C-D-Q-C-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-K-Y-E-I-M-L-M-V-S-G-Q-L-N-Q-N-Q-A-Q-A-V-N-D-E-L-K-A-V-F-G-K-T-E-I-T-E-E-Y-L-G-Q-K-T-L-E-Y-P-I-K-K-E-V-T-A-H-Y-F-N-L-F-L-T-S-D-G-K-S-V-H-E-Y-K-R-L-A-S-I-R-T-D-V-L-R-I-L-I-L-N-T-E-K-E-F-G-Y-R-A-S-Q-N-A-K-K-V-A-L-A-K-Q-K-Q-A-R-Y-N-D-I-M-K-Q-V-Q-E-N-G-Y-F-Q-I-K-G-S-K-R-N-S-R-V-E-K-A-G-A-K-E-V-W-M-L-R-E-K-F-G-E-D-L-P-E-Q-K-I-P-V-L-R-K-V-N-L-T-R-K-P-T-P-N-K-S-S-E-N-K-Q-K-V-E-K-Q-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-D-I-T-K-Q-P-A-N-N-I-S-S-D-D-K-K-E-V-A-K-A-S-A-K-S-S-V-E-G-A-K-R-K-T-F-Y-K-S-R-S-R-K-L-C-H-F-C-A-K-G-I-L-K-V-D-Y-K-D-V-N-T-L-R-K-N-L-N-S-Y-A-K-I-V-S-R-R-Q-S-G-N-C-N-L-H-Q-R-H-V-S-N-A-I-K-K-A-R-I-M-A-L-L-P-F-V-K-D"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-L-K-D-V-P-S-L-G-K-A-D-S-V-V-N-V-A-N-G-Y-A-K-N-F-L-F-K-N-K-L-A-E-P-Y-T-E-R-G-Q-K-R-L-D-L-K-V-I-K-R-N-E-Q-H-D-L-L-A-L-E-A-K-N-L-A-K-Q-L-E-G-V-V-L-E-Y-D-I-R-T-N-E-E-D-K-A-F-G-T-I-G-F-K-Q-I-V-D-D-L-S-K-K-H-I-F-V-T-K-D-M-L-D-S-K-M-K-L-D-I-G-E-H-R-V-K-I-N-I-F-E-G-I-H-A-T-I-L-V-K-V-S-K-A-Q"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-N-F-Q-N-L-A-N-Q-M-K-K-M-Q-R-E-M-E-K-K-L-A-E-F-E-E-K-E-Y-Q-Y-E-Y-K-K-L-I-K-T-T-L-K-G-N-L-R-I-V-K-L-E-I-N-K-D-L-I-D-P-E-D-P-D-T-L-Q-D-M-V-T-E-A-I-N-E-A-L-G-D-L-E-K-K-R-D-E-L-S-N-S-I-T-P-P-I-K-F-P-G-F"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-N-R-F-I-K-S-A-T-S-L-K-D-C-I-N-D-S-K-K-E-V-C-L-I-G-R-S-N-V-G-K-S-T-I-I-N-G-L-A-N-A-K-I-A-Q-T-S-K-T-P-G-R-T-V-T-M-N-F-Y-E-I-S-N-Q-R-I-V-D-L-P-G-Y-G-Y-A-R-I-K-K-S-Q-K-E-E-I-S-L-F-L-S-D-Y-L-N-H-R-K-N-L-V-G-I-F-L-I-L-D-L-G-V-I-T-D-Q-D-I-E-I-V-R-L-L-T-T-L-D-V-E-Y-Y-I-V-F-N-K-I-D-K-Y-P-K-S-A-Y-I-N-N-K-E-K-I-L-D-A-L-K-V-N-E-D-R-I-L-L-I-S-A-K-N-K-Q-N-L-N-N-L-M-L-K-I-I-D-V-I-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-N-R-A-E-K-R-K-V-L-P-D-P-V-Y-N-S-V-L-V-T-R-A-I-N-A-I-M-L-D-G-K-K-G-I-A-Q-K-I-L-Y-G-S-F-D-L-I-A-Q-K-T-Q-K-D-P-L-E-I-F-N-K-A-V-E-N-I-M-P-R-L-E-L-K-V-R-R-I-A-G-A-N-Y-Q-V-P-T-D-V-S-P-E-R-K-V-T-L-A-L-R-W-L-V-T-L-S-R-K-R-H-E-K-T-M-L-D-K-I-A-N-E-I-I-D-A-S-N-N-T-G-A-S-V-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-M-R-M"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-I-I-H-A-K-D-L-R-S-G-H-T-F-T-L-D-G-K-I-Y-L-V-I-E-N-S-F-N-K-T-A-M-R-E-G-I-V-K-C-K-V-K-N-L-R-T-G-S-I-T-T-E-V-L-T-G-M-K-L-E-Q-A-N-I-E-K-V-K-M-S-F-V-Y-Q-D-Q-N-S-F-V-F-M-N-N-E-T-Y-E-Q-I-E-V-P-A-K-L-L-E-Y-E-K-N-F-I-T-E-N-T-E-A-L-I-M-R-Y-E-D-E-I-L-G-V-N-L-P-D-Q-V-V-I-E-I-D-Y-A-E-D-A-V-Q-G-N-S-V-N-N-A-L-K-K-A-T-L-V-T-G-Y-V-I-E-V-P-Q-F-I-K-S-K-E-K-V-I-V-S-T-V-D-G-K-Y-V-S-R-A-N"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-R-L-L-V-N-N-K-K-A-K-Y-N-Y-E-L-L-D-K-Y-E-A-G-I-S-L-S-G-N-E-V-K-S-L-A-L-H-H-G-K-L-D-D-S-Y-V-I-I-R-K-N-E-A-Y-L-L-N-L-L-I-P-K-Y-K-F-D-T-S-K-V-L-N-E-T-R-T-R-K-L-L-L-H-K-S-E-I-L-K-I-D-L-I-K-K-Q-H-S-L-V-I-I-P-Y-Q-I-Y-F-V-N-N-K-I-K-V-S-I-Y-L-A-R-P-K-K-R-Y-D-K-R-Q-T-I-K-E-R-E-I-N-K-K-I-R-K-Y"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-I-G-V-G-I-D-V-V-S-I-D-R-F-Q-A-K-K-S-D-E-F-I-K-K-L-L-T-E-H-E-Q-N-K-Y-K-T-V-I-G-E-S-N-Q-N-I-F-L-A-I-R-W-S-L-K-E-A-I-F-K-A-L-K-T-W-D-E-F-T-Q-L-E-I-R-K-I-H-G-A-Y-E-C-S-L-N-E-K-I-K-L-H-L-S-I-S-H-E-G-Q-R-L-V-A-M-A-V-A-E-R-I"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-N-H-F-D-L-K-K-V-P-P-S-I-K-E-D-F-S-E-I-L-K-I-I-N-Q-C-F-S-S-H-F-K-V-K-N-N-L-F-Y-E-L-S-F-V-S-E-K-Q-S-L-Q-L-N-S-S-L-R-N-K-E-Y-V-A-D-I-I-S-V-C-L-W-E-N-A-E-I-I-T-P-L-L-G-E-I-F-I-C-S-K-K-I-A-K-D-A-I-K-Y-D-V-N-F-W-Y-L-L-I-R-M-I-I-H-G-L-L-H-L-L-E-F-D-H-E-Q-S-D-A-Y-E-Y-V-T-L-T-I-Q-E-Q-I-V-N-K-V-I-K-T-A-K-K-K-I-W-K-N-Q-E-L-L-S-L-L-G"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-I-A-S-G-S-K-Q-Y-R-V-K-L-N-D-E-I-Y-V-E-K-L-N-S-Q-V-G-E-K-I-V-F-D-K-V-Y-F-V-N-N-T-F-G-K-P-F-V-K-G-A-S-V-T-C-E-V-L-K-Q-G-R-Q-K-K-I-N-V-I-K-H-I-S-Q-K-H-H-L-K-K-Y-G-H-R-Q-P-Y-T-K-L-K-V-V-A-I-N-H-G"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-R-V-K-G-G-P-T-T-R-R-R-R-K-K-W-L-N-Q-A-E-G-T-F-G-T-R-H-A-S-Y-K-V-A-K-Q-T-V-I-K-S-A-K-Y-A-F-R-D-R-K-N-K-K-R-E-F-R-A-L-W-I-Q-R-L-N-G-A-L-R-E-L-G-V-T-Y-S-V-F-I-N-L-L-K-K-Q-Q-I-T-I-N-R-K-M-L-S-E-I-A-I-H-D-H-E-A-F-K-K-L-V-K-E-V-T-G-K"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-K-T-K-K-H-L-L-T-Q-E-G-L-K-K-L-Q-A-E-L-R-L-L-V-D-V-K-R-A-D-V-I-K-L-I-Q-E-A-R-E-Q-G-D-L-S-E-N-A-D-Y-D-S-A-K-A-T-Q-S-E-I-E-S-R-I-T-E-I-Q-D-I-L-N-H-Y-E-I-I-K-E-V-D-T-K-N-K-R-V-I-V-G-A-K-V-T-I-H-D-H-S-D-E-C-N-Y-T-Y-E-I-V-G-P-I-E-S-D-P-A-E-N-K-I-S-H-E-S-P-V-A-K-A-I-M-D-K-K-E-G-E-S-A-E-V-I-G-I-E-H-P-Y-K-V-T-I-K-K-I-V-L"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-K-T-E-L-I-A-Q-L-K-K-T-I-I-T-V-K-D-F-P-K-P-G-I-L-F-Y-D-I-T-P-I-L-L-D-P-K-L-F-D-Q-V-I-S-V-M-A-E-V-A-K-K-S-N-A-D-M-I-A-S-P-E-S-R-G-F-L-F-G-V-P-L-A-N-K-L-K-L-P-F-V-L-V-R-K-Q-N-K-L-P-R-A-T-F-S-A-S-Y-D-L-E-Y-G-K-N-N-V-I-E-I-H-Q-D-A-I-K-P-N-S-K-V-M-I-V-D-D-L-L-A-T-A-G-T-V-D-A-I-S-R-L-V-K-Q-A-K-S-E-V-V-S-Y-S-F-L-I-R-L-K-D-L-G-G-I-D-K-L-D-Q-T-K-P-I-D-Y-I-L-E-Y"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-L-T-K-E-Q-F-I-E-S-L-K-E-M-T-I-V-E-I-N-D-V-I-K-A-I-E-E-A-F-G-V-S-A-A-A-P-I-A-A-A-A-A-A-P-A-A-A-A-P-T-E-A-T-V-V-L-V-S-A-G-D-K-K-V-E-V-I-K-L-V-R-E-V-T-G-L-G-L-M-D-A-K-K-A-V-D-T-P-P-A-T-I-K-E-N-M-N-I-E-E-A-K-A-L-K-A-K-F-E-A-V-G-A-K-V-D-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-K-A-I-I-Q-K-K-I-E-H-V-N-K-I-A-G-L-L-K-E-A-K-S-F-V-V-F-E-Y-S-T-M-T-A-K-A-I-T-A-L-R-R-K-V-K-T-S-A-N-Q-M-F-V-L-K-N-N-I-L-K-R-A-I-K-E-A-G-I-D-G-F-D-D-D-I-K-N-Q-I-A-V-V-I-G-L-E-D-A-F-L-P-I-K-A-V-H-E-Y-V-T-A-N-E-K-V-K-Y-V-C-G-Y-L-E-N-E-K-L-S-A-A-E-L-S-E-I-A-V-L-P-S-R-D-E-L-Y-S-M-F-L-S-V-L-Q-A-P-V-R-K-F-M-Y-A-L-K-A-V-A-D-T-K-Q-Q"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-A-N-E-K-S-Y-R-Q-N-Q-K-A-N-L-L-T-K-G-F-K-T-S-L-K-N-Q-L-K-K-T-K-A-S-K-D-K-K-D-V-E-Q-V-Y-S-L-A-D-K-L-A-K-N-N-R-I-S-K-N-K-A-R-R-L-K-S-R-A-A-R-W-S-N-S-A-T-A-A-S-R"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-Y-Y-V-A-L-D-V-G-S-R-T-L-G-I-A-T-G-D-G-E-F-K-I-A-S-P-Y-C-V-I-S-F-N-Q-Y-D-F-R-Q-C-L-A-E-L-K-E-K-T-A-S-F-F-Y-D-F-K-F-V-I-G-M-P-K-N-I-D-Q-T-K-S-S-T-T-E-M-V-E-N-F-I-E-L-L-K-A-N-Y-K-N-E-V-I-I-Y-D-E-S-Y-T-S-I-I-A-D-Q-L-L-I-D-N-Q-I-K-A-K-K-R-K-E-K-I-D-K-L-A-A-F-V-I-L-Q-S-F-F-D-D-D-R-Y-P-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-K-I-K-T-L-R-L-E-A-T-I-H-K-L-L-S-Q-A-I-S-T-E-I-N-N-S-L-I-K-T-S-V-I-T-A-I-K-L-S-D-D-K-S-V-A-K-I-Y-I-D-C-L-I-P-N-N-I-A-K-T-L-Q-A-Y-K-D-A-T-G-V-F-R-H-V-L-S-K-H-L-T-I-R-R-I-P-Q-L-V-F-Y-Y-D-D-S-I-S-K-G-A-K-I-D-Q-I-L-A-E-I-K-Q-E-K-K-E-N-H-E"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-E-F-K-T-Y-S-D-F-F-D-K-N-A-N-S-I-I-N-W-F-E-G-E-L-A-K-V-R-S-G-R-A-N-L-K-I-L-D-N-V-R-A-E-Y-Y-G-E-Q-T-P-L-I-E-M-A-S-L-S-I-P-E-P-R-E-I-L-I-K-P-Y-E-K-S-S-V-N-L-I-Q-A-A-L-L-K-A-N-L-N-L-T-P-V-V-D-G-D-K-I-R-I-K-L-P-L-L-T-E-E-N-R-K-E-N-V-K-K-V-K-A-V-G-E-K-A-K-Q-E-V-R-F-I-R-R-D-T-L-N-K-I-K-S-D-K-I-A-D-K-D-L-N-K-Y-F-E-E-Q-V-D-K-I-T-K-K-Y-I-D-Q-I-D-S-I-L-A-K-K-E-K-D-L-L-S-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-S-K-D-K-K-T-E-I-I-K-K-F-Q-K-N-D-A-D-V-G-S-V-F-V-Q-V-A-V-L-T-E-E-I-K-L-L-T-E-H-L-L-K-N-K-K-D-F-I-S-K-R-G-L-Y-T-K-V-S-K-R-K-N-L-L-N-Y-L-K-Q-N-D-L-N-A-Y-R-N-L-I-S-E-L-E-L-R-H-S"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-T-S-F-G-Y-R-G-K-R-V-S-P-I-P-P-K-D-K-I-D-Y-K-E-V-D-L-L-R-K-F-I-T-E-R-G-K-I-L-P-R-R-I-T-G-L-T-A-K-Q-Q-R-D-L-T-V-A-I-K-R-A-R-L-L-A-L-L-P-F-V-N-Q-E-G"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-R-R-T-W-L-G-D-R-L-K-P-L-N-S-E-I-G-K-A-S-P-G-W-G-T-T-P-I-M-G-A-L-I-A-L-F-G-V-F-L-I-I-I-L-Q-I-A-N-N-S-L-L-L-E-G-V-N-E-G-V-P-Q-S-P-A-G-Q-G-Y-G-Y-Y-P-Q-S-R"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-T-V-A-Q-V-F-V-V-G-I-L-V-A-L-V-L-I-T-A-F-A-V-Y-T-A-F-G-P-P-S-K-K-L-A-D-P-F-E-M-H-E-D"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-W-M-P-L-V-L-A-A-E-E-A-E-S-R-G-F-S-L-N-L-N-L-L-E-T-N-I-I-N-I-A-I-V-F-G-L-L-I-F-L-A-R-G-Y-F-G-R-V-L-G-E-R-K-S-E-I-E-N-G-I-R-E-V-E-N-R-G-R-Q-A-E-Q-E-L-A-T-A-R-Q-N-L-S-Q-A-Q-V-Q-A-Q-Q-I-L-A-S-A-R-T-N-A-E-R-V-R-A-Q-V-L-D-Q-A-Q-I-D-I-A-R-V-R-E-T-V-D-Q-D-L-R-N-E-Q-Q-R-I-L-T-Q-V-R-L-K-V-V-G-D-A-L-A-R-L-R-E-R-L-P-G-E-L-D-E-A-T-Q-R-R-L-L-D-R-S-I-Q-L-L-D"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-Q-Q-G-K-D-S-E-Q-I-A-Q-R-Y-A-E-A-L-K-E-L-A-L-S-E-T-G-L-L-E-Q-F-G-N-D-T-D-G-M-L-Q-V-M-E-E-S-P-D-F-E-R-F-L-V-V-P-I-I-A-M-A-D-K-K-R-L-L-V-E-A-F-G-G-K-V-H-P-Y-M-L-N-F-L-Q-L-M-V-D-R-R-R-I-A-L-L-R-P-V-C-T-S-Y-Q-R-I-L-R-E-L-Q-Q-T-T-L-A-E-V-I-S-A-V-P-L-S-E-E-Q-A-S-A-L-I-E-R-I-R-R-R-T-A-A-V-R-V-E-L-R-R-R-V-D-P-E-L-L-G-G-M-I-I-K-I-G-D-E-V-I-D-A-S-L-R-G-Q-L-R-K-L-T-L-Q-L-T-L-S"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-P-K-A-G-I-H-P-R-Y-E-E-A-R-I-V-C-G-C-G-A-I-Y-E-T-R-S-T-K-P-G-V-T-N-V-E-I-C-A-N-C-H-P-F-F-T-G-Q-Q-K-I-V-D-A-E-G-R-V-D-R-F-L-K-K-Y-G-N-V-Q-P-R-T-K-R"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-E-N-E-R-T-T-E-N-F-Q-P-Q-D-P-S-Y-A-E-A-A-T-T-E-A-S-A-A-E-A-T-G-F-I-A-R-I-D-Q-L-A-A-E-N-S-D-L-Q-K-K-L-A-D-Y-E-Q-K-Y-T-R-L-M-A-D-F-D-N-F-R-K-R-T-Q-R-E-K-D-E-L-A-Y-F-V-S-A-K-L-L-K-D-I-L-P-V-F-D-N-F-D-R-A-R-A-F-A-Q-P-D-N-E-R-E-E-K-L-H-N-S-Y-Q-Q-V-Y-R-Q-F-L-S-V-L-E-K-M-G-V-T-A-M-E-A-I-G-Q-P-F-D-P-A-Q-H-E-A-I-L-R-E-E-S-A-G-V-S-Q-E-T-V-V-A-E-L-Q-K-G-Y-L-L-A-D-K-V-L-R-P-A-M-V-K-V-A-I-P-E-A-G-S"} +{"text": "### FUNCTION Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 ### SEQUENCE -M-D-P-V-Q-I-R-S-L-S-L-E-A-L-A-Y-L-G-D-A-V-W-E-L-H-V-R-T-R-V-L-L-P-P-R-R-L-Q-W-L-H-G-D-T-V-A-C-V-R-A-S-A-Q-A-K-L-A-T-C-L-S-P-H-L-T-V-E-E-A-D-W-L-R-R-G-R-N-A-G-G-T-V-P-R-R-L-D-P-A-T-Y-R-L-A-T-A-F-E-A-L-L-G-Y-L-F-L-A-D-R-D-R-L-G-V-I-L-H-L-C-D-E-F-Q-H-H-H-G-P-D-T-P-S-P-E-A"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-T-H-R-P-A-R-V-G-E-L-I-K-R-E-V-S-D-M-L-L-R-G-Q-I-K-D-P-R-V-G-A-G-L-V-S-V-T-D-V-E-V-T-G-D-L-R-Q-A-K-I-F-V-S-I-F-G-T-P-E-A-Q-K-L-T-M-M-A-L-A-E-V-T-G-F-V-R-Q-E-I-G-H-R-I-R-L-R-Y-T-P-E-I-A-F-V-Q-D-R-S-L-E-R-G-A-R-I-T-R-L-I-D-E-I-R-A-E-E-E-A-R-A-A-H-K-E-E-G-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-P-L-T-Q-D-R-K-Q-E-L-I-G-T-Y-Q-V-H-E-T-D-T-G-S-P-E-V-Q-V-A-M-L-S-D-R-I-N-Q-L-T-E-H-L-R-S-H-P-K-D-F-S-S-R-R-G-L-L-K-L-I-G-R-R-K-Q-L-L-A-Y-L-A-A-N-E-A-D-R-Y-R-A-L-V-D-R-L-G-L-R-R"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-G-Q-T-F-L-H-R-I-G-T-D-L-V-H-I-P-R-I-E-G-M-L-E-R-Y-G-K-Q-F-L-N-R-V-Y-T-E-G-E-Q-H-Y-C-L-A-S-K-P-H-R-A-N-R-L-A-G-R-W-A-A-K-E-A-V-T-K-A-L-G-T-G-W-R-G-V-G-Y-R-D-I-E-V-V-R-L-A-S-G-E-P-T-I-C-L-N-G-R-A-V-L-L-V-E-R-F-G-R-L-D-W-Q-V-S-F-S-H-D-R-E-Y-A-V-A-T-V-S-V-I-G-F-F"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-L-T-Q-Q-K-I-R-I-R-L-Q-A-F-D-H-G-L-L-D-Q-S-C-S-K-I-V-D-T-A-N-R-T-N-A-A-A-V-G-P-I-P-L-P-T-R-I-R-R-Y-C-V-L-R-S-P-H-V-D-K-D-S-R-E-H-F-E-T-R-T-H-R-R-I-I-D-I-Y-Q-P-S-A-K-T-I-D-A-L-M-R-L-D-L-P-A-G-V-D-I-E-V-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-T-R-A-I-L-R-P-V-T-A-D-P-L-Y-A-S-R-L-V-T-M-M-T-N-K-L-M-K-E-G-K-K-A-T-A-E-R-I-L-Y-S-A-L-E-R-V-Q-E-R-T-G-R-E-P-L-D-V-F-N-Q-A-V-L-N-C-T-P-R-I-E-V-K-A-R-R-V-G-G-A-T-Y-Q-V-P-M-E-V-R-Q-E-R-G-T-S-L-A-L-R-W-L-V-Q-F-S-R-K-R-S-G-K-S-M-V-D-K-L-S-N-E-L-M-D-A-A-N-D-T-G-S-A-V-R-K-R-E-E-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-Y"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-D-E-V-K-A-V-A-R-F-I-R-M-S-P-F-K-V-R-R-I-L-D-Q-I-R-G-R-S-Y-Q-D-A-L-I-I-L-Q-F-M-P-H-A-A-T-E-P-I-K-K-V-L-E-S-A-A-A-N-A-E-H-N-F-S-L-D-R-R-A-L-V-V-S-T-A-F-A-D-G-G-P-V-L-K-R-F-R-A-G-D-R-G-R-A-R-P-V-R-K-R-T-S-H-I-T-V-A-V-R-S-T-S-E-V-E"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-F-R-K-Q-Q-R-G-R-M-N-G-A-A-C-R-G-N-E-I-E-F-G-T-Y-A-L-Q-A-L-E-P-V-W-M-T-S-R-Q-I-E-A-A-R-R-A-M-T-R-Y-I-R-R-G-G-K-I-Y-I-R-V-F-P-D-K-P-V-T-Q-R-A-A-E-T-R-M-G-S-G-K-G-A-P-E-Y-W-V-C-V-V-K-P-G-R-I-L-F-E-I-D-G-V-A-E-E-I-A-R-E-A-M-R-L-A-A-A-K-L-P-I-K-S-R-F-I-V-K-S-E-T-A-P-A-E-E-P-T-N-A-P-T"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-R-K-E-K-I-G-L-V-V-S-D-A-M-Q-K-T-V-V-V-A-V-E-N-R-V-P-H-P-K-Y-K-K-I-V-V-R-T-R-K-F-K-A-H-D-E-E-N-R-C-K-V-G-D-R-V-R-I-L-E-S-P-P-L-S-K-T-K-R-W-V-V-L-D-I-L-D-E-A-R-N-P"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-Q-S-R-L-S-V-A-D-N-T-G-A-R-E-L-L-C-I-R-V-L-G-S-T-V-G-S-K-G-L-T-K-G-G-G-N-R-R-Y-A-F-V-G-D-I-V-V-A-V-V-K-D-A-A-P-N-M-G-V-K-K-S-E-V-V-R-A-V-V-V-R-T-R-Q-A-I-R-R-D-N-G-M-V-I-R-F-D-D-N-A-A-V-I-I-D-K-N-G-N-P-R-G-T-R-V-F-G-P-V-A-R-E-L-R-E-K-N-F-T-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-T-N-N-G-A-G-K-A-R-H-K-F-H-V-K-K-G-D-T-V-Q-V-I-S-G-K-D-K-G-K-V-G-K-V-S-E-V-L-P-T-A-G-K-V-I-V-E-G-V-N-M-Q-T-K-H-V-K-P-Q-G-D-Q-Q-G-Q-T-L-R-R-E-A-P-I-Y-S-C-K-V-M-L-Y-S-D-K-K-K-Q-A-S-R-V-G-H-T-V-T-D-A-G-K-K-V-R-V-L-K-K-T-G-E-I-L-D-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-T-P-V-R-M-K-D-K-Y-N-R-E-V-V-P-R-L-Q-E-Q-F-N-Y-T-N-L-M-Q-V-P-K-I-S-K-I-V-I-N-R-G-L-G-E-A-S-Q-N-A-K-A-L-D-G-S-I-A-E-V-A-R-I-A-G-Q-K-P-V-V-T-R-A-K-K-A-I-A-G-F-K-L-R-A-G-V-P-V-G-V-T-V-T-L-R-A-R-R-M-Y-E-F-L-D-R-L-V-S-V-A-L-P-R-I-R-D-F-R-G-V-S-P-K-A-F-D-G-R-G-N-Y-T-L-G-L-R-E-Q-L-I-F-P-E-I-E-Y-D-S-V-D-K-I-R-G-M-D-I-T-I-C-T-T-A-K-T-D-E-E-G-R-A-L-L-A-A-L-G-M-P-F-R-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-A-V-N-D-T-L-A-D-M-L-T-R-I-R-N-A-S-I-V-K-H-D-I-V-P-V-P-S-T-R-M-T-R-S-V-A-E-V-L-K-M-E-G-L-I-L-E-Y-Q-D-Q-G-E-G-K-D-R-Q-L-L-L-T-L-K-Y-A-G-R-Q-R-R-P-L-I-T-N-L-K-R-V-S-R-P-G-L-R-V-Y-A-N-R-K-E-L-P-R-V-L-G-G-I-G-I-A-I-I-S-T-S-Q-G-V-M-T-D-R-D-A-R-R-A-G-V-G-G-E-V-L-C-Y-V-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-L-P-I-A-I-P-P-K-V-E-V-T-L-D-G-R-R-V-V-V-K-G-P-K-G-T-L-D-L-T-L-P-D-S-V-E-V-V-R-E-D-G-R-L-L-V-T-R-R-G-E-S-R-R-A-R-E-Q-H-G-L-G-R-T-L-V-A-N-M-V-T-G-V-T-T-G-F-T-K-P-M-Q-I-A-G-V-G-Y-R-V-A-L-T-G-R-K-L-T-I-N-A-G-F-S-H-P-I-E-I-E-L-P-A-G-I-D-I-E-V-D-P-K-A-S-A-I-A-G-T-R-N-Q-Q-G-F-N-F-V-I-K-G-F-D-K-Q-A-V-G-D-L-A-A-K-I-R-D-I-R-P-P-E-P-Y-K-G-K-G-I-R-Y-T-A-E-K-I-L-L-K-A-G-K-S-G-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-K-V-D-R-K-T-A-T-H-R-R-H-Q-R-I-R-R-K-I-A-G-T-P-E-Q-P-R-L-A-V-Y-R-S-N-R-H-I-Y-A-Q-V-I-D-D-V-H-Q-R-T-L-V-A-A-S-T-L-E-A-P-L-R-S-G-E-E-G-T-A-T-C-E-A-A-T-A-V-G-R-L-V-A-E-R-A-K-E-K-G-I-T-A-V-V-F-D-R-G-G-K-L-Y-H-G-R-V-K-A-V-A-D-A-A-R-E-A-G-L-D-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-S-L-R-L-E-D-A-V-P-Q-S-G-S-R-H-R-K-L-R-V-G-R-G-H-S-A-G-Q-G-K-T-S-G-R-G-M-R-G-Q-K-C-R-S-G-G-G-V-R-P-G-F-E-G-G-Q-I-P-L-Y-M-R-L-P-K-L-K-G-F-E-L-V-N-P-S-S-Y-T-I-V-N-L-K-Q-L-R-D-L-P-A-D-S-E-V-N-I-E-T-L-L-D-A-G-I-L-T-A-T-S-G-P-L-R-V-L-G-D-G-E-A-H-V-A-L-Q-I-T-A-A-Y-F-T-A-S-A-R-E-K-I-E-A-A-G-G-T-C-T-V-E-A"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-P-L-L-N-L-V-L-D-N-G-S-R-F-V-A-D-V-E-K-H-S-S-I-A-L-W-A-P-P-E-G-G-I-E-G-N-Y-Q-R-R-L-R-G-I-G-Y-R-T-Q-I-I-T-A-K-G-L-G-D-I-S-R-F-L-L-E-S-H-G-V-R-P-A-H-L-G-K-K-D-K-R-V-F-T-L-P-P-E-L-A-I-Y-M-D-T-L-P-A-S-A-K-G-F-V-L-W-I-I-E-G-K-V-L-S-L-F-E-L-E-S-L-V-G-L-P-A-A-V-P-K-L-K-V-I-V-E-V-G-S-D-Y-N-I-R-W-M-P-L-E-Q-A-V-S-K-M-A-E-G-R"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-P-T-V-G-W-I-A-L-L-A-F-F-V-V-S-I-A-L-V-V-W-G-R-N-G-F"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-E-V-L-K-W-V-V-T-I-V-V-L-L-F-V-A-I-F-A-F-G-F-L-S-G-D-P-S-R-N-P-G-R-G-S-G-Q"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-I-P-R-E-K-R-V-E-I-A-L-T-Y-I-F-G-I-G-P-S-R-A-T-Q-I-L-L-S-T-G-I-N-P-N-L-R-V-R-E-L-T-D-V-Q-V-S-L-L-R-E-E-I-E-Q-K-Y-Q-V-E-G-D-L-R-R-F-E-N-I-N-I-K-R-L-M-D-I-G-C-L-R-G-R-R-H-R-L-G-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-R-G-G-R-K-T-V-A-G-K-K-K-A-A-A-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-P-T-R-G-G-Q-K-K-K-V-R-R-N-V-P-S-G-V-A-H-I-Q-S-T-F-N-N-T-I-V-T-I-A-D-T-V-G-D-V-I-S-W-A-S-A-G-S-S-G-F-K-G-A-K-K-G-T-P-F-A-A-Q-Q-A-A-E-S-A-G-R-R-A-I-D-S-G-M-R-Q-C-E-V-M-V-S-G-P-G-A-G-R-E-T-A-I-R-A-L-Q-A-V-G-L-E-I-T-L-I-R-D-V-T-P-I-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-L-E-Y-P-E-E-L-K-Y-L-D-S-H-E-Y-L-R-V-E-G-D-T-V-V-V-G-V-T-S-Y-A-V-D-Q-L-G-D-I-V-F-V-S-L-P-E-E-G-D-R-I-N-R-G-D-S-F-G-S-I-E-S-V-K-A-V-E-E-L-Y-A-P-L-S-G-T-V-L-S-V-N-T-V-A-V-E-D-P-A-L-I-G-S-D-P-Y-G-D-G-W-L-I-K-V-R-L-A-D-P-A-D-E-L-G-E-T-M-T-A-E-E-Y-R-E-R-V-E-G"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Y-T-R-P-L-A-R-L-I-E-H-L-Q-R-L-P-G-I-G-P-K-T-A-Q-R-L-A-F-H-L-L-R-R-P-K-S-E-A-L-Q-L-A-Q-A-L-V-E-A-T-E-Q-I-G-V-C-S-R-C-F-N-L-S-A-E-D-P-C-D-I-C-R-Q-P-G-R-Q-G-E-T-I-C-V-V-A-E-P-R-D-L-V-A-I-E-R-T-R-E-F-K-G-H-Y-H-V-L-G-G-L-I-N-P-M-E-G-I-G-P-E-Q-L-R-I-K-E-L-L-Q-R-V-G-A-D-T-V-K-E-V-I-L-A-I-N-P-S-T-E-G-E-M-T-T-M-Y-L-S-K-Y-V-K-V-L-G-P-R-V-T-R-I-A-F-G-L-P-V-G-G-D-L-E-Y-A-D-E-M-T-L-A-R-A-L-E-G-R-R-E-I"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-S-K-G-F-G-P-M-G-Q-F-Q-E-A-L-K-R-V-K-Q-I-Q-E-G-S-A-K-L-Q-D-E-L-A-A-L-S-I-E-G-V-A-G-G-G-L-V-K-V-T-L-S-G-N-Q-E-P-T-G-V-T-I-D-P-Q-L-L-S-E-S-K-E-V-V-E-D-L-L-L-T-A-Y-K-D-A-Y-T-K-S-A-E-T-M-K-A-K-M-Q-E-L-T-G-G-M-E-L-P-P-G-L-G-F"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-N-P-R-D-I-V-E-Q-V-T-A-L-A-E-P-V-A-E-Q-L-G-L-Q-L-V-A-V-A-Y-Q-T-H-T-K-P-A-T-L-R-V-D-I-R-H-P-T-E-G-T-G-L-D-D-C-E-K-M-S-R-A-L-E-A-L-L-D-T-R-D-D-L-I-I-G-A-Y-N-L-E-V-S-S-P-G-V-E-R-V-L-T-T-D-R-E-F-M-A-F-R-G-F-P-V-M-V-K-T-F-G-P-V-D-G-K-K-Q-W-E-G-R-L-L-E-R-D-G-E-N-V-Y-L-T-I-A-G-R-R-V-A-L-P-R-P-Q-V-A-R-V-Q-L-V-Q-S-L-P"} +{"text": "### FUNCTION Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase ### SEQUENCE -M-A-I-E-R-G-A-K-V-R-I-L-R-K-E-S-Y-W-Y-R-E-V-G-T-V-A-S-V-D-K-S-E-K-T-I-Y-P-V-T-V-R-F-E-K-V-N-Y-S-G-I-N-T-N-N-F-G-V-S-E-L-E-E-V-E-A"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-V-K-R-G-N-V-A-R-K-R-R-K-K-I-L-K-L-A-K-G-F-R-G-S-H-S-K-L-F-T-A-A-N-Q-Q-V-M-K-A-L-R-N-A-Y-R-H-R-R-T-K-K-R-D-F-R-S-L-W-I-V-R-I-N-A-Q-A-R-T-E-G-L-S-Y-S-R-L-I-D-G-L-H-K-A-D-V-A-L-N-R-K-M-L-A-Q-L-A-V-T-D-P-E-A-F-A-E-V-A-R-V-A-K-S-A-R-P-V"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-G-T-K-I-V-L-K-K-D-V-D-T-L-G-K-A-G-T-L-V-E-V-A-P-G-Y-A-R-N-Y-L-I-P-Q-G-L-A-V-K-A-T-P-G-L-V-K-E-A-E-F-R-Q-A-K-R-R-E-I-E-A-K-H-R-A-D-A-L-E-T-K-K-T-L-E-A-L-G-F-Y-E-V-F-A-P-V-G-E-D-G-N-Q-L-F-G-T-V-T-N-Q-D-V-A-E-V-V-A-S-K-A-G-I-T-I-D-R-R-E-I-T-I-E-E-P-I-K-R-T-G-V-Y-T-V-K-A-R-I-F-Q-D-V-V-A-T-L-R-L-Q-V-N-A-A-G"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-V-R-E-S-V-L-V-M-V-G-G-A-L-G-S-L-A-R-Y-W-V-G-L-G-I-S-Q-W-A-G-A-P-P-F-L-F-G-T-L-L-V-N-L-V-G-S-F-M-L-G-G-L-F-A-W-S-V-A-L-R-I-D-P-A-L-L-L-L-A-G-T-G-F-C-G-G-F-T-T-F-S-A-L-S-I-E-C-L-V-L-L-Q-K-G-D-Y-P-T-A-M-G-Y-L-L-G-S-L-L-G-G-L-A-A-G-W-A-G-Y-L-A-A-K-A-L"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-V-F-D-L-L-E-R-L-F-N-R-N-K-T-G-S-A-T-V-A-K-D-R-L-K-M-V-L-A-V-D-R-T-E-I-A-P-Q-T-I-E-Q-I-R-K-E-I-L-D-V-I-V-R-Y-F-E-I-D-E-N-E-K-F-D-V-T-L-E-R-E-R-G-S-T-A-I-I-A-N-V-P-I-R-R-I-R-P-E-H-I"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-P-L-K-R-P-E-L-D-D-P-E-I-R-E-L-L-E-Q-G-M-G-H-N-T-Y-G-E-P-F-W-P-N-D-I-L-I-F-G-V-V-I-L-G-T-I-F-G-V-I-A-L-A-V-L-D-P-A-K-M-G-E-P-A-D-P-F-N-T-P-L-H-I-L-P-E-W-Y-F-Y-P-V-F-Q-I-L-R-V-V-P-N-K-L-L-G-V-V-L-M-A-A-I-P-I-G-L-A-L-V-P-F-I-E-N-V-N-K-F-Q-N-P-F-R-R-P-L-A-T-A-V-F-L-I-G-T-V-V-T-M-Y-L-G-I-G-A-M-I-P-D-I-P-K-S-L-T-L-G-L-F"} +{"text": "### FUNCTION Involved in the binding and/or turnover of quinones at the Q site of Photosystem II ### SEQUENCE -M-T-A-T-L-S-N-F-L-W-S-I-F-W-G-G-V-V-V-A-L-G-A-A-A-L-T-A-I-S-R-I-D-R-I-R"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-L-W-L-A-L-F-F-G-R-F-S-R-L-E-A-P-Q-R-L-V-I-K-K-R-S-D-R-G-Q-A-N-L-P-M-I-N-E-R-I-R-F-P-K-I-R-A-I-D-A-D-G-T-Q-L-G-I-M-H-P-R-D-A-L-R-I-A-E-E-R-N-L-D-L-V-V-V-S-E-D-A-Q-P-P-V-C-R-I-M-D-Y-G-K-Y-K-F-E-Q-E-K-R-A-K-E-A-R-K-K-Q-H-T-A-D-V-K-E-V-K-M-R-Y-T-I-G-E-H-D-Y-Q-V-R-L-R-D-T-I-R-F-L-K-D-G-D-K-V-K-A-T-I-M-F-R-G-R-E-I-Q-H-A-N-L-A-K-D-L-L-M-Q-L-A-A-D-S-A-E-I-G-E-V-Q-Q-E-P-S-V-E-G-R-N-M-I-M-I-L-S-P-K-R-T"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-N-Q-P-V-V-E-T-A-E-L-M-R-R-V-E-Q-L-V-D-A-A-A-N-R-Y-R-I-T-V-Q-V-A-N-R-A-K-R-R-R-Y-E-D-L-N-D-D-D-G-N-F-K-P-V-L-R-A-I-F-E-M-S-D-E-M-N-E-P-E-I-I-G-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-S-E-R-V-E-K-I-L-E-D-L-K-A-L-S-L-L-E-A-A-E-L-V-K-G-I-E-E-V-F-G-V-K-A-E-A-P-A-G-G-G-M-M-V-M-P-G-V-M-P-G-A-P-A-A-A-A-P-A-E-P-V-E-E-Q-T-E-F-T-V-M-L-E-E-V-P-A-D-K-K-I-A-I-L-K-V-A-R-E-I-T-G-L-G-L-K-E-A-K-D-L-V-E-A-A-P-K-A-V-K-E-G-V-N-K-D-D-A-A-T-I-K-K-K-L-E-E-A-G-A-K-A-S-I-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-G-K-R-P-V-K-E-A-L-V-G-D-L-Q-K-L-L-E-K-S-S-V-V-M-V-I-D-Y-R-G-L-S-V-A-E-I-T-G-L-R-R-R-M-R-E-H-G-G-T-C-V-V-A-K-N-T-L-M-G-V-A-T-R-E-T-A-W-R-N-I-D-P-L-L-A-G-P-S-A-F-L-F-G-N-E-K-L-K-E-M-L-K-T-Y-E-D-F-A-R-E-T-K-K-T-E-F-R-G-A-V-V-D-G-T-L-V-T-L-D-G-L-K-A-I-A-D-L-P-P-K-E-V-L-L-A-Q-F-A-G-A-L-K-V-L-P-T-K-I-A-V-G-I-N-Q-V-P-T-K-V-A-V-G-I-N-E-V-P-A-G-L-A-R-V-L-E-A-L-R-K-Q-K-E-E-Q-Q-Q-P-Q-A-A-A"} +{"text": "### FUNCTION Covalently attaches a chromophore to Cys residue of phycobiliproteins ### SEQUENCE -M-S-D-W-Q-T-V-R-T-W-L-A-G-T-Y-S-N-R-A-Q-A-M-A-E-P-V-W-F-I-P-V-T-L-W-Y-V-E-V-A-G-L-F-G-E-G-A-G-F-F-T-E-Q-V-S-E-H-T-P-N-Q-P-Y-R-S-R-V-L-Q-L-L-D-N-P-L-R-L-E-N-Y-R-L-K-D-Q-K-V-W-A-G-A-A-K-D-P-E-R-L-G-R-L-R-A-D-D-C-E-Q-L-P-G-C-T-L-Y-L-E-R-R-G-E-T-F-T-G-K-M-Q-P-G-G-G-C-R-L-F-P-G-D-A-S-Y-V-E-I-E-F-E-L-G-E-R-L-F-F-T-L-D-R-G-F-E-A-T-T-G-E-Q-T-W-G-S-R-A-G-A-Y-R-Y-L-K-Q-L-H"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-L-K-S-T-T-R-H-V-H-I-F-A-A-D-I-R-N-D-N-F-I-A-S-D-T-K-L-T-L-D-V-D-P-D-N-E-F-I-W-N-D-P-A-L-Q-K-V-Y-S-E-F-D-R-L-V-A-A-Y-T-G-L-A-L-T-E-Y-N-L-R-R-I-G-S-D-L-E-N-F-I-R-G-L-L-Q-Q-G-E-I-A-Y-N-L-D-S-R-V-L-N-F-S-M-G-R-P-Q-V-R-G-P-G-Q-I-E-N-R-P-G-Q"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-Q-Q-W-L-E-I-G-K-V-V-A-A-Q-G-L-R-G-E-V-R-V-Q-P-A-T-D-F-A-E-R-L-T-R-P-G-A-R-L-V-G-R-S-L-D-D-G-R-V-F-R-L-Q-S-G-R-A-I-P-G-K-D-L-F-V-C-R-F-E-G-V-E-E-R-N-A-A-E-K-L-V-G-S-T-L-W-I-G-A-A-E-R-P-V-L-A-A-G-E-F-W-L-P-D-L-M-G-V-R-V-F-R-Q-D-T-G-E-A-I-G-E-V-S-D-M-T-R-A-G-N-D-L-L-V-I-R-L-S-G-G-K-T-V-M-V-P-F-V-H-A-L-V-P-V-V-D-L-E-A-G-R-I-E-V-V-A-I-P-G-L-L-D-P-E-A-A-E-A-D-E-A"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-G-E-K-T-R-K-I-L-V-D-N-R-K-A-R-F-E-Y-E-I-L-E-T-Y-S-A-G-L-A-L-L-G-T-E-V-K-A-I-R-A-G-R-A-N-L-N-D-A-F-A-R-I-H-H-G-E-V-L-L-Y-N-M-N-I-S-P-L-Q-T-A-G-A-F-A-H-D-P-L-R-T-R-K-L-L-L-K-R-R-E-I-H-K-L-T-G-R-V-E-E-K-G-L-T-L-I-P-L-K-L-Y-L-E-G-S-W-V-K-L-D-L-G-L-A-R-G-K-K-L-Y-D-K-R-E-D-I-K-K-R-E-T-K-R-D-I-E-R-A-M-R-R"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-R-I-K-L-V-A-V-G-R-L-R-E-E-A-Y-E-R-A-C-A-E-Y-A-R-R-L-A-A-Y-A-R-L-E-L-V-E-V-R-D-A-R-I-A-D-S-R-A-G-L-L-K-E-G-Q-A-L-L-D-Q-L-H-P-G-E-H-A-V-L-L-D-S-G-G-K-Q-F-T-S-V-E-L-A-D-W-L-E-N-H-T-V-Q-E-P-V-F-I-V-G-S-S-H-G-V-A-P-M-V-R-E-R-A-Q-M-V-W-S-L-S-K-L-T-F-P-H-E-L-A-R-V-I-V-L-E-Q-L-Y-R-A-V-T-I-L-A-G-H-P-Y-H-H-G"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-S-N-D-F-R-T-G-T-T-I-E-L-D-G-Q-V-W-R-V-I-E-F-L-H-V-K-P-G-K-G-S-A-F-V-R-T-K-L-K-N-V-M-T-G-N-V-N-E-R-T-F-R-A-G-E-T-L-P-Q-A-V-V-E-K-R-D-M-Q-F-V-Y-P-Q-G-D-N-E-Y-V-F-M-D-M-E-S-Y-E-Q-E-A-L-T-R-E-T-L-G-D-G-A-K-Y-L-K-E-G-M-S-V-S-I-L-K-W-Q-E-R-V-I-G-V-D-L-P-N-T-V-V-L-Q-V-V-E-T-D-P-G-V-K-G-D-T-A-Q-G-G-T-K-P-A-K-V-E-T-G-A-E-V-M-V-P-L-F-I-T-I-G-E-K-I-K-I-D-T-R-D-N-S-Y-L-G-R-E-N"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-R-A-Y-R-L-G-E-D-L-G-T-G-A-K-C-V-K-F-L-I-N-L-A-S-T-P-S-M-A-V-V-P-T-A-V-E-L-C-I-Q-A-A-V-D-D-P-V-G-E-A-R-W-Q-S-W-F-D-Q-W-L-L-E-L-Q-S-A-G-A-V-E-L-T-L-R-L-T-D-D-A-E-I-R-R-L-N-A-R-F-R-G-V-D-A-P-T-D-V-L-S-F-E-F-E-A-D-D-T-Q-A-L-I-A-E-E-P-L-Y-L-G-D-I-V-V-S-V-P-T-A-T-R-Q-A-R-E-F-G-H-T-L-E-V-E-L-A-W-L-A-V-H-G-L-L-H-L-L-G-W-D-H-P-D-E-Q-S-W-R-A-M-V-T-Q-Q-A-R-L-L-K-G-V-N-V-V-Y-D-W-P-S-V-Y-P-V-G"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-V-V-S-V-L-G-L-D-V-G-S-K-R-I-G-V-A-G-C-D-P-T-G-L-I-A-S-G-L-E-T-I-V-R-C-N-L-G-A-D-L-D-A-I-R-H-W-I-E-R-R-R-A-Q-A-V-V-I-G-L-P-R-N-M-N-G-S-L-G-P-Q-A-H-R-I-Q-H-F-G-Q-Q-L-A-R-V-I-D-V-P-I-D-Y-V-D-E-R-L-S-T-V-Q-A-G-R-A-L-Q-S-V-S-A-T-R-R-K-A-L-I-D-Q-Q-A-A-A-I-I-L-Q-Q-W-L-D-I-R-R-C-Q-H-R-P-T-Q-E-S-L-D-E-R-H-I-D-T-E-R"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-T-G-E-I-F-F-V-A-G-L-V-F-V-L-T-L-V-G-M-A-I-G-F-G-V-L-K-L-R-G-E-G-K-E-A"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-V-F-E-G-N-L-Q-D-T-R-D-L-K-F-A-I-V-I-A-R-F-N-D-L-V-V-G-K-L-L-S-A-C-E-D-S-L-R-R-H-G-V-A-V-G-P-D-S-H-Q-V-D-Y-A-W-V-P-G-S-F-E-I-P-M-V-A-R-Q-L-A-L-S-G-R-Y-D-A-I-V-C-L-G-A-V-I-R-G-Q-T-S-H-Y-D-H-V-A-S-E-V-A-K-G-I-Q-A-L-A-F-Q-T-G-V-P-V-T-F-G-V-L-T-T-D-T-M-Q-Q-A-I-E-R-A-G-I-K-S-N-L-G-W-E-Y-G-E-N-A-I-E-M-A-T-L-T-R-K-I-R-H-L-V-A-V-R-A-V-Q-P-E-L-P-E-Q-T-P-P-S-L-L-Q"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-V-F-V-A-D-H-L-L-R-K-I-E-T-M-N-S-K-N-E-K-R-V-I-K-T-W-S-R-A-S-T-I-V-P-Q-M-I-G-H-T-I-A-V-H-N-G-K-E-H-L-P-V-Y-V-T-E-Q-M-V-G-Q-K-L-G-E-F-V-P-T-R-V-F-K-G-H-A-G-K-D-K-K-G-K-R"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-P-Q-R-I-P-L-W-M-V-G-V-M-A-G-L-G-V-I-A-I-L-G-L-F-F-Y-G-S-Y-A-G-L-G-A-G"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-S-K-D-P-K-N-P-G-V-E-L-N-R-T-S-L-Y-M-G-L-V-L-V-L-V-I-I-L-L-F-S-N-Y-F-I-N"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-A-Q-E-I-I-R-S-I-E-A-E-Q-M-K-T-Q-L-P-V-L-H-I-G-D-T-V-K-V-N-V-R-I-R-E-G-G-K-E-R-I-Q-A-F-E-G-T-I-I-S-M-A-R-A-G-I-N-R-T-V-T-V-R-R-I-F-Q-G-I-G-V-E-R-V-F-L-V-H-S-P-R-I-E-S-M-T-V-T-R-L-G-K-V-R-R-A-K-L-Y-Y-L-R-D-R-I-G-K-A-T-R-V-K-Q-K-I-T-R-K-A-N"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-V-Y-A-I-V-E-T-G-G-K-Q-V-L-V-Q-P-G-R-F-Y-D-V-E-L-L-A-L-D-V-E-A-A-L-T-F-D-K-V-L-L-V-R-H-E-G-G-A-V-V-G-R-P-T-V-E-G-A-A-V-Q-G-R-I-L-Q-H-G-K-A-A-K-V-T-V-Y-K-M-R-P-K-K-G-Y-R-R-K-K-G-H-R-Q-R-F-T-R-V-M-I-E-S-I-D-F-E-G-R-S-F-T-A-E-A-K-A-E-A-V-S-S-T"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-T-E-T-L-E-R-K-S-V-Q-R-K-P-M-P-L-Y-K-V-L-L-H-N-D-D-H-T-P-M-N-Y-V-I-E-V-L-M-K-T-I-P-K-M-Q-P-S-K-A-R-K-I-M-L-E-A-H-N-G-G-V-A-V-V-I-V-C-A-L-E-H-A-E-F-Y-S-E-S-L-N-R-H-N-L-T-S-T-Y-E-P-D-C"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-N-Q-R-N-D-N-F-I-D-K-S-F-T-V-M-A-D-M-I-L-Q-M-M-P-V-K-R-Q-A-K-E-A-F-A-Y-Y-R-D-G-M-A-A-Q-A-D-G-D-Y-A-E-A-L-E-Y-Y-N-E-A-L-K-L-E-E-D-A-Y-D-R-S-F-I-H-Y-N-I-G-L-I-H-A-A-N-G-A-H-D-V-A-L-D-Y-Y-D-K-A-L-E-E-N-P-R-L-P-Q-A-L-N-N-I-A-V-I-H-H-F-R-G-A-K-V-E-E-E-G-Q-P-E-Q-A-E-E-H-Y-A-K-A-A-A-A-W-I-R-A-V-R-L-A-P-D-N-Y-I-E-A-Q-N-W-L-K-T-T-G-R-F-E-L-L-Y"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-P-F-G-L-G-L-P-E-I-L-V-I-G-V-I-A-L-L-I-F-G-P-K-K-L-P-E-M-G-S-A-L-G-K-A-I-R-G-F-K-S-G-V-S-D-E-P-A-P-Q-Q-S-A-S-K-E-T-A-P-N-P-P-Q-S-L-P-S-G-K-D-S"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-S-F-W-S-K-V-K-D-F-V-G-F-G-D-P-L-E-Y-E-E-D-G-E-E-Y-E-Q-V-Y-R-E-E-N-K-R-E-E-A-R-R-A-T-A-G-T-A-A-A-A-T-P-T-A-A-A-Q-A-S-D-A-A-P-M-G-S-G-P-A-R-K-R-V-R-A-G-N-V-I-G-M-P-N-S-G-V-N-E-V-L-V-I-E-P-R-S-F-E-E-A-P-Q-I-V-Q-H-L-R-D-R-K-S-V-I-L-N-L-T-L-M-D-S-D-Q-A-Q-R-S-V-D-F-V-A-G-A-T-F-A-I-D-G-H-Q-E-R-V-G-D-G-I-F-L-F-T-P-S-S-V-M-I-S-T-E-M-P-S-Q-L-R-Q-A-N-Q-A-F-G-G-N-F-R-L-N-P-E-A-P-R-R-A-Q-G"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-S-P-L-Q-E-I-G-T-A-V-R-M-T-A-I-F-W-I-G-C-G-L-A-Y-P-L-I-F-T-G-F-A-Q-V-A-F-P-D-Q-A-N-G-S-L-V-R-N-A-Q-N-Q-V-I-G-S-S-L-I-G-Q-K-F-T-S-E-R-Y-F-H-G-R-P-S-S-I-D-Y-K-A-E-A-S-G-A-S-Q-L-A-P-T-N-K-V-L-I-E-R-V-K-A-D-A-A-A-F-E-A-Q-N-G-T-K-P-T-I-D-L-V-T-T-P-G-S-G-L-D-P-H-I-T-P-A-G-A-A-V-Q-T-A-R-V-S-R-A-R-N-L-A-P-E-Q-V-R-K-L-V-S-Q-Y-T-E-G-R-F-L-G-I-F-G-E-P-R-V-N-V-L-A-L-N-L-A-L-D-G-I-R-R"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-E-L-R-L-F-V-G-L-G-N-P-G-L-Q-Y-T-Q-T-R-H-N-A-G-F-L-A-V-D-A-L-A-K-R-W-Q-C-S-W-V-E-K-S-R-F-K-G-Y-L-A-E-G-A-G-P-G-G-R-A-I-L-L-K-P-T-T-Y-M-N-H-S-G-Q-S-V-R-A-V-A-D-Y-F-R-L-P-P-Q-Q-L-L-V-L-Y-D-E-V-A-L-P-L-G-K-I-R-L-R-P-E-G-S-A-A-G-H-N-G-I-K-S-L-I-E-H-L-G-T-N-Q-F-A-R-L-R-I-G-I-G-R-E-P-P-P-P-V-L-T-N-Y-V-L-G-K-F-A-P-E-E-Q-E-Q-L-P-A-I-L-D-G-C-V-E-A-V-E-A-V-L-A-K-G-L-E-K-A-M-S-I-Y-N-A-R-S-F-G-S-P-P-D-P"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-I-E-P-I-L-L-G-M-V-L-G-F-V-P-V-T-I-A-G-L-L-V-A-A-W-L-Q-Y-K-Q-G-N-P-S-G-L-G-E-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-T-K-Y-E-T-M-Y-I-L-R-P-D-L-T-D-E-I-I-D-Q-T-I-T-R-Y-Q-T-L-L-A-E-Q-G-A-A-P-V-E-T-Q-H-R-G-K-R-R-L-A-Y-E-L-K-K-F-K-E-G-I-Y-V-Q-M-N-Y-D-A-P-T-T-A-V-A-E-L-E-K-A-F-R-L-S-E-E-V-I-R-F-L-T-V-R-E-E-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-Q-D-V-I-E-M-E-G-T-V-V-E-S-L-P-N-A-M-F-R-V-E-L-D-N-S-F-N-I-L-A-H-I-S-G-K-I-R-R-N-Y-I-K-I-L-P-G-D-R-V-K-V-E-L-T-P-Y-D-L-T-K-G-R-I-T-Y-R-L-R-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-N-V-S-K-T-E-Q-D-M-R-K-A-I-E-A-T-A-G-N-F-A-T-I-R-T-G-R-A-S-T-S-L-L-D-R-I-N-V-E-Y-Y-G-Q-P-T-P-L-K-T-L-A-T-I-T-T-P-D-A-S-T-V-L-I-Q-P-Y-D-P-S-S-L-R-L-I-E-K-T-I-L-E-S-D-L-G-L-P-P-S-N-D-G-K-T-I-R-L-N-I-P-P-L-T-A-E-R-R-K-D-L-V-K-V-L-R-N-L-A-E-E-G-R-V-A-V-R-N-I-R-R-H-A-I-D-E-V-R-K-E-E-K-D-A-K-V-S-E-D-E-A-R-R-L-Q-D-E-V-Q-K-L-T-D-K-S-I-Q-Q-I-E-K-L-F-E-A-K-E-K-E-I-T-T-V"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-N-I-K-S-A-I-K-R-V-D-V-A-E-R-N-R-Q-R-N-I-A-Y-K-S-M-I-K-T-F-T-K-K-F-M-T-R-L-G-E-Y-A-Q-S-P-S-E-A-V-L-T-E-V-Q-A-L-L-N-Q-T-F-S-R-I-D-K-A-I-K-A-G-V-I-H-T-N-T-G-A-R-K-K-S-R-L-D-A-A-L-R-T-A-L-A-K-A-Q-A-K-A-G"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-L-C-P-F-C-S-Y-S-D-N-R-V-L-E-S-R-L-A-E-E-G-E-S-V-R-R-R-R-E-C-K-Q-C-R-R-R-F-T-T-Y-E-R-I-E-F-V-P-T-V-V-I-K-R-N-G-R-R-E-A-F-D-R-S-K-V-L-R-G-V-M-I-A-C-E-K-T-D-V-P-A-E-L-I-E-Q-L-V-D-D-L-Q-A-E-L-Q-Q-R-S-S-R-E-V-T-S-A-E-I-G-E-M-V-L-A-L-L-K-P-L-N-E-V-A-Y-V-R-F-A-S-V-Y-R-K-F-K-G-V-A-D-F-V-S-E-L-Q-T-F-E-A-N-A-E-L-D-S-L-K-A-R-L-E-R-L-A-A-A-H-D-Q-S-A-D"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-S-G-T-K-R-A-L-A-D-I-I-R-R-P-L-I-T-E-K-G-T-R-L-L-E-E-N-K-Y-L-F-E-V-T-P-G-A-N-K-I-Q-I-A-Q-A-I-E-E-L-F-S-V-K-V-T-K-V-N-T-F-N-P-P-A-R-Q-R-R-V-G-K-Y-L-G-T-R-S-S-Y-K-R-A-I-V-T-L-Q-E-G-D-S-I-T-L-F-P-E-V"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-A-A-P-A-I-Y-Q-T-D-K-V-L-R-F-E-V-P-G-S-R-R-P-S-T-Y-F-F-A-L-V-L-T-L-G-G-L-G-F-L-F-A-G-L-S-P-F-V-E-T-N-L-L-P-F-S-D-T-R-G-L-T-R-F-P-Q-G-V-T-M-I-F-Y-G-A-L-A-T-L-F-S-L-Y-Y-W-L-V-L-A-L-D-V-G-S-G-Y-N-E-F-D-K-Q-N-K-K-V-T-L-F-R-R-G-F-P-G-K-N-R-I-I-E-I-V-H-P-L-E-N-I-L-G-L-K-V-Q-I-K-E-G-L-N-P-R-R-A-Y-F-L-K-L-K-G-A-R-D-L-R-L-S-P-V-G-Q-P-Q-P-L-A-A-V-E-D-Q-V-S-A-I-A-R-F-L-N-I-G-V-E-G-I"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-S-A-Y-R-F-R-R-A-H-R-L-L-K-T-D-E-F-S-S-V-F-S-L-R-Q-Q-R-S-N-A-F-F-Q-V-F-A-R-P-N-G-L-D-H-A-R-V-G-L-V-V-G-K-K-V-A-K-R-A-V-R-R-N-Y-I-K-R-C-V-R-E-W-F-R-L-N-Q-Q-G-L-D-G-V-D-Y-V-V-R-A-K-T-A-F-T-R-E-Q-R-A-E-A-V-T-A-L-Q-A-L-F-A-K-L-A-R-C-R-A-S-S-S-S"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-L-T-H-Q-D-V-A-R-I-A-K-L-A-R-I-N-V-S-E-A-E-I-A-A-T-A-D-Q-L-N-N-I-F-G-L-I-E-K-M-Q-A-V-D-T-A-G-I-E-P-M-A-H-P-Q-D-V-S-L-R-L-R-D-D-V-V-T-E-P-N-R-R-E-A-F-Q-A-V-A-P-Q-V-E-K-G-L-F-L-V-P-K-V-I-E"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-L-L-N-I-L-H-Y-P-D-E-R-L-H-T-V-A-K-P-V-E-V-F-D-A-A-L-Q-Q-Q-I-D-D-M-F-E-T-M-Y-E-A-K-G-I-G-L-A-A-T-Q-V-D-Y-H-R-R-L-V-V-M-D-I-S-E-E-R-D-E-R-R-V-F-I-N-P-E-I-V-E-K-D-G-E-T-V-Y-E-E-G-C-L-S-V-P-G-I-Y-D-K-V-T-R-A-E-R-V-K-V-K-A-Q-D-R-D-G-K-P-F-E-L-E-A-D-G-L-L-A-I-C-I-Q-H-E-L-D-H-L-N-G-V-V-F-V-E-R-L-S-Q-M-K-Q-Q-R-I-K-T-K-L-K-K-R-E-K-Q-N-M"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-L-S-G-K-L-I-E-K-L-P-P-Q-V-V-V-D-V-N-G-V-G-Y-E-V-D-V-P-M-T-T-F-Y-Q-L-P-A-L-G-Q-P-C-T-L-F-T-H-L-A-V-R-E-D-A-H-L-L-Y-G-F-A-S-K-E-E-R-Q-T-F-R-Q-L-I-K-V-T-G-I-G-A-K-I-A-L-A-I-L-S-G-M-T-A-D-E-L-A-I-A-V-A-S-E-D-I-K-R-L-S-A-V-P-G-I-G-K-K-T-A-E-R-L-V-L-E-L-R-G-K-L-A-T-G-G-N-L-T-V-P-G-G-L-P-F-A-A-T-P-D-E-K-S-D-I-V-N-A-L-L-A-L-G-Y-N-E-K-E-A-A-A-A-T-K-S-L-P-A-D-V-T-V-S-E-G-V-R-L-A-L-K-S-L-M-K-V"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-L-N-I-E-D-K-K-A-V-V-A-E-V-S-A-Q-L-A-E-A-Q-T-L-V-I-A-E-Y-R-G-I-E-V-S-S-M-T-K-L-R-A-Q-A-R-E-N-G-V-Y-L-R-V-L-K-N-T-L-V-R-R-A-V-E-G-T-P-F-A-G-L-A-D-Q-M-V-G-P-L-V-Y-A-V-S-A-D-P-V-A-A-A-K-V-L-H-Q-F-A-K-A-D-D-K-I-I-V-K-A-G-S-Y-D-G-Q-V-L-N-A-A-Q-V-A-E-L-A-S-I-P-S-R-E-E-L-L-S-K-L-L-Y-V-M-Q-A-P-V-A-G-F-A-R-A-L-A-A-L-A-E-K-Q-A-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-I-T-K-E-D-I-L-E-A-V-A-G-L-T-V-M-E-L-N-D-L-V-K-A-F-E-E-K-F-G-V-S-A-A-A-V-A-V-A-G-P-A-G-A-G-A-A-A-A-E-E-K-T-E-F-D-V-V-L-S-A-A-G-D-N-K-V-G-V-I-K-V-V-R-A-I-T-G-L-G-L-K-E-A-K-D-L-V-D-G-A-P-K-N-V-K-E-G-V-A-K-A-E-A-E-D-I-V-K-Q-L-T-E-A-G-A-K-A-E-I-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-K-G-R-V-A-I-T-A-K-S-K-V-P-A-L-E-A-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-K-V-R-L-T-N-G-F-E-V-I-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-S-L-D-T-A-G-V-K-D-R-K-Q-A-R-S-K-Y-G-A-K-R-P-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-E-V-P-K-R-E-I-L-P-D-P-K-F-G-S-Q-D-L-S-K-F-M-N-V-V-M-I-D-G-K-K-S-V-A-E-R-I-I-Y-G-A-L-E-Q-I-E-K-K-T-G-K-N-A-I-E-V-F-N-T-A-L-S-N-A-K-P-V-V-E-V-K-S-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-R-P-S-R-R-M-A-L-A-M-R-W-L-R-D-A-A-R-K-R-G-E-K-S-M-D-L-R-L-A-G-E-L-I-D-A-A-E-G-R-G-G-A-M-K-K-R-D-E-V-H-R-M-A-E-A-N-K-A-F-S-H-F-R-F"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-S-Q-K-I-R-I-R-L-K-A-F-D-Y-N-L-I-D-R-S-A-Q-E-I-V-E-T-A-K-R-T-G-A-V-V-K-G-P-V-P-L-P-T-K-I-E-R-F-N-V-L-R-S-P-H-V-N-K-T-S-R-D-Q-L-E-I-R-T-H-L-R-L-M-D-I-V-D-P-T-D-K-T-V-D-A-L-M-K-L-D-L-P-A-G-V-D-V-E-I-K-L-Q"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-Q-E-R-L-L-Q-V-I-L-A-P-I-V-S-E-K-S-T-M-I-A-E-K-N-Q-Q-V-A-F-R-V-A-K-D-A-T-K-P-E-I-K-A-A-V-E-M-L-F-N-V-K-V-D-G-V-S-T-V-N-V-K-G-K-V-K-R-F-G-R-T-I-G-R-R-S-D-W-K-K-A-Y-V-S-L-V-D-G-Q-E-L-D-L-T-A-T-P-A-A-A-E"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-Q-K-K-G-P-F-V-D-L-H-L-L-K-K-V-D-A-V-R-A-T-S-D-K-R-P-I-K-T-W-S-R-R-S-T-I-L-P-D-F-I-G-L-T-I-A-V-H-N-G-R-T-H-V-P-V-Y-V-S-E-N-M-V-G-H-K-L-G-E-F-S-L-T-R-T-F-K-G-H-A-A-D-K-K-A-K-K-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-R-V-S-A-N-L-K-S-V-R-L-S-A-Q-K-C-R-L-V-A-D-L-V-R-G-K-S-V-D-Q-A-L-N-I-L-A-F-S-P-K-K-G-A-V-I-I-K-K-V-L-E-S-A-I-A-N-A-E-H-N-E-G-A-D-I-D-T-L-R-V-T-S-I-F-V-D-K-G-A-S-L-K-R-F-T-A-R-A-K-G-R-G-N-R-I-E-K-Q-T-C-H-I-S-L-T-V-G-N"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-T-R-L-K-Y-R-K-Q-H-K-G-R-N-T-G-I-A-T-R-G-N-K-V-S-F-G-D-F-G-L-K-A-I-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-H-I-K-R-G-G-R-I-W-I-R-I-F-P-D-K-P-I-T-S-K-P-A-E-V-R-M-G-G-G-K-G-S-P-E-Y-Y-V-A-E-I-Q-P-G-K-M-L-Y-E-M-D-G-V-S-E-E-L-A-R-E-A-F-R-L-A-A-A-K-L-P-I-A-T-V-F-V-T-K-Q-V-G-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-T-K-V-V-R-T-L-T-G-V-V-V-S-D-K-M-D-K-T-V-T-V-L-V-E-R-K-V-K-H-P-I-Y-G-K-I-I-R-R-S-K-K-F-H-A-H-D-E-N-N-E-F-K-A-G-D-L-V-V-I-S-E-S-R-P-L-S-K-T-K-S-W-V-V-T-G-L-V-E-K-S-R-Q-V"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-M-L-E-V-A-D-N-T-G-A-R-H-V-Q-C-I-K-V-L-G-G-S-K-R-R-Y-A-S-V-G-D-I-I-K-V-S-I-K-D-A-A-P-R-G-R-V-K-K-G-D-V-Y-N-A-V-V-V-R-T-A-K-G-V-R-R-P-D-G-S-L-I-K-F-D-S-N-A-A-V-L-L-N-N-K-L-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-R-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-R-K-I-R-K-G-D-E-V-V-V-I-T-G-K-D-K-G-K-R-G-T-V-L-R-V-L-E-T-K-L-V-V-E-G-V-N-V-A-K-K-H-Q-K-P-N-P-V-R-G-V-A-G-G-I-V-E-K-T-M-P-I-D-A-S-N-V-A-I-F-N-P-A-S-Q-K-A-D-R-V-G-F-K-V-L-E-D-G-R-K-V-R-V-F-K-S-S-G-E-V-I-G-A"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-R-L-Y-D-F-Y-K-D-S-V-V-P-E-L-M-K-Q-F-G-Y-K-S-I-M-Q-V-P-R-I-E-K-I-T-V-N-M-G-V-G-E-A-V-A-D-K-K-V-M-E-F-A-V-G-D-L-E-K-I-A-G-Q-K-P-V-V-T-T-A-R-K-S-I-A-G-F-K-I-R-D-D-Y-P-V-G-C-K-V-T-L-R-R-E-R-M-Y-E-F-L-D-R-L-V-T-I-A-L-P-R-V-R-D-F-R-G-V-S-A-K-S-F-D-G-R-G-N-Y-N-M-G-V-K-E-Q-I-I-F-P-E-I-E-Y-D-K-I-D-A-L-R-G-M-N-I-T-I-T-T-S-A-K-T-D-E-E-A-R-A-L-L-A-A-F-K-F-P-F-K-G"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-R-L-A-L-I-N-R-E-E-K-R-V-K-L-A-E-K-F-S-A-K-R-E-A-L-I-A-T-I-N-N-Q-N-L-S-E-E-E-R-F-A-A-R-L-Q-L-Q-Q-L-P-R-N-A-S-P-V-R-Q-R-R-R-C-A-V-T-G-R-P-R-G-V-F-R-K-F-G-L-G-R-N-K-L-R-E-I-A-M-K-G-E-I-P-G-V-V-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-H-D-P-I-S-D-M-L-T-R-I-R-N-G-Q-H-A-S-K-V-K-V-S-M-P-S-S-K-L-K-I-A-L-A-Q-V-L-K-E-E-G-Y-I-E-D-F-A-I-A-G-E-E-K-K-P-V-L-D-I-Q-L-K-Y-Y-A-G-R-P-V-I-E-R-I-E-R-V-S-R-P-G-L-R-V-Y-K-G-S-T-E-I-P-K-V-M-N-G-L-G-V-A-I-L-S-T-S-K-G-V-M-T-D-R-K-A-R-A-A-G-I-G-G-E-L-L-C-V-V-A"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-N-P-V-A-I-P-A-G-V-E-V-K-F-G-A-A-D-V-T-V-K-G-A-L-G-S-L-S-T-A-L-C-N-D-V-E-V-K-L-D-N-G-Q-L-T-F-A-A-K-N-D-S-K-F-A-R-A-M-S-G-T-L-R-A-L-L-N-N-M-V-N-G-V-S-K-G-F-E-K-K-L-Q-L-V-G-V-G-Y-R-A-Q-A-Q-G-D-T-L-N-L-S-L-G-F-S-H-P-V-A-H-K-M-P-A-G-I-K-V-E-T-P-T-Q-T-E-I-L-V-K-G-A-D-K-Q-L-V-G-Q-V-A-A-E-I-R-A-Y-R-S-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-V-V-V-L-K-E-T-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-Q-T-R-L-R-R-A-R-K-T-R-A-R-I-A-E-L-K-M-V-R-L-S-V-H-R-T-N-S-H-I-Y-A-Q-I-I-D-E-T-G-N-K-V-L-A-S-A-S-S-L-E-A-D-V-R-S-A-M-A-N-G-G-N-V-A-A-A-A-V-I-G-K-R-I-A-E-K-A-K-A-A-G-I-E-Q-V-A-F-D-R-S-G-F-K-Y-H-G-R-M-K-A-L-A-D-A-A-R-E-H-G-L-V-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-K-H-E-M-E-D-R-G-D-G-L-V-E-K-M-I-S-V-N-R-V-T-K-V-V-K-G-G-R-I-M-A-F-S-A-L-T-V-V-G-D-G-D-G-G-I-G-M-G-K-G-R-S-K-E-V-P-V-A-V-Q-K-A-M-E-Q-A-R-H-N-M-M-K-I-K-L-Y-N-G-T-V-K-H-T-V-E-G-R-H-G-A-T-R-V-L-I-Q-P-A-K-D-G-T-G-V-K-A-G-G-P-M-R-A-I-F-D-A-M-G-I-H-N-V-S-A-K-I-H-G-S-T-N-P-Y-N-V-V-R-A-T-L-D-G-L-S-K-I-N-T-P-A-Q-I-A-A-K-R-G-L-S-I-E-D-I-L-G-V-G-H-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-L-L-N-T-V-Q-P-G-V-G-A-K-H-A-K-R-R-V-G-R-G-I-G-S-G-L-G-K-T-C-G-R-G-H-K-G-Q-K-S-R-A-G-G-F-H-K-V-G-F-E-G-G-Q-M-P-L-Q-R-R-L-P-K-R-G-F-K-S-L-T-A-R-F-V-C-E-V-R-L-S-E-L-N-L-L-P-V-D-E-I-D-L-L-A-L-K-Q-A-G-L-V-A-A-Q-A-Q-V-A-K-V-V-L-S-G-K-V-E-R-A-V-K-L-R-G-I-S-V-T-A-G-A-R-A-A-I-E-A-A-G-G-S-I-E"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-D-T-I-Q-M-Q-G-E-V-L-E-N-L-P-S-A-T-F-K-I-K-L-E-N-G-H-V-V-L-G-H-I-S-G-K-M-R-M-H-Y-I-R-I-L-P-G-D-K-V-T-V-E-L-T-P-Y-D-L-S-R-A-R-I-V-F-R-A-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-N-H-A-H-A-V-I-G-L-Q-A-I-F-G-V-G-Q-T-R-A-Q-Q-I-C-A-A-A-S-V-N-P-S-T-K-V-K-D-L-T-E-A-E-M-E-A-L-R-D-Q-V-A-K-F-T-V-E-G-D-L-R-R-E-I-T-M-S-I-K-R-L-M-D-M-G-C-Y-R-G-F-R-H-R-R-G-L-P-C-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-K-A-I-A-G-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-A-N-T-A-V-R-V-R-K-K-V-R-K-S-V-S-E-G-I-V-H-V-H-A-S-F-N-N-T-I-I-T-I-T-D-R-Q-G-N-A-L-S-W-A-T-S-G-G-A-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-H-A-G-K-V-A-Q-E-Y-G-V-K-N-L-E-V-R-I-K-G-P-G-P-G-R-E-S-A-V-R-A-L-N-S-L-G-F-K-I-T-S-I-S-D-V-T-P-V-P-H-N-G-C-R-P-P-K-K-R-R-I"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-K-K-A-K-R-N-P-L-L-A-R-L-A-G-R-L-E-L-T-L-D-V-R-S-D-A-A-A-L-P-P-P-A-L-I-R-R-A-C-Q-A-A-L-R-R-D-V-K-Q-A-Q-I-S-I-V-I-V-D-A-A-E-G-R-Q-L-N-N-D-Y-R-G-K-D-Y-A-T-N-V-L-S-F-A-L-N-E-G-E-P-V-E-G-L-P-L-F-G-D-L-V-L-C-A-P-V-V-E-Q-E-A-A-E-Q-N-K-A-L-M-A-H-Y-A-H-L-L-V-H-G-M-L-H-L-Q-G-F-D-H-E-E-D-A-E-A-E-A-M-E-V-L-E-T-V-I-V-K-Q-L-G-Y-P-D-P-Y-H-E-E-H-I"} +{"text": "### FUNCTION Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein ### SEQUENCE -M-I-R-R-V-L-L-L-S-L-A-L-L-L-A-G-C-A-N-E-A-L-F-R-P-K-P-A-L-E-S-A-A-D-A-P-F-S-V-S-G-R-L-S-A-N-L-D-G-K-G-H-V-A-N-F-D-W-R-H-L-P-P-R-D-E-V-A-I-N-S-P-L-G-N-T-V-A-K-V-L-R-D-P-G-G-V-T-L-L-A-D-G-K-R-W-Q-A-D-D-V-E-S-L-T-R-Q-V-M-G-W-P-L-P-L-S-N-L-V-W-W-I-R-G-L-P-A-P-G-V-E-S-R-V-D-A-D-G-N-L-E-Q-Q-G-W-H-I-R-F-I-R-D-A-D-V-D-S-D-H-P-K-R-V-E-M-Q-R-E-G-L-T-V-K-V-V-V-Q-S-W-Q"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-S-Y-E-L-I-A-A-K-R-V-D-L-G-T-G-A-S-R-R-L-R-R-A-G-K-L-P-A-V-V-Y-G-A-G-K-D-A-V-S-L-E-L-D-H-N-T-L-Y-H-A-V-K-H-A-D-F-H-T-S-V-L-E-L-V-I-D-G-Q-K-E-Q-V-K-V-A-A-F-Q-M-H-P-Y-K-Q-Q-V-L-H-I-D-F-A-R-V"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-G-I-R-L-I-V-G-L-G-N-P-G-P-E-Y-E-K-T-R-H-N-A-G-F-W-L-V-D-E-L-C-W-Q-F-K-G-N-W-R-S-E-G-K-F-H-G-D-V-A-R-I-Q-I-E-G-Q-D-V-W-L-L-K-P-M-T-Y-M-N-L-S-G-Q-A-V-L-A-L-A-H-F-Y-K-I-L-P-D-E-I-L-V-V-H-D-E-L-D-L-A-P-G-V-A-R-F-K-Q-G-G-G-H-G-G-H-N-G-L-K-D-I-A-A-R-L-S-S-P-A-F-W-R-L-R-L-G-I-G-H-P-G-D-K-K-E-V-A-N-F-V-L-K-K-P-R-A-E-E-Q-Q-A-L-D-E-A-V-L-A-S-L-R-E-L-P-R-A-V-S-G-K-M-A-E-A-M-K-A-L-H-T-E-A-K"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-F-D-F-G-E-R-R-I-G-V-A-V-G-D-T-I-L-G-I-P-H-P-L-A-T-I-D-T-A-V-T-D-E-R-F-A-A-I-A-R-L-I-E-E-W-Q-P-R-Q-L-V-V-G-L-P-M-H-P-D-G-E-E-H-E-L-S-A-L-S-R-R-F-A-N-R-L-K-G-R-F-G-L-P-V-W-L-V-D-E-R-Y-T-S-V-I-A-E-Q-L-L-E-E-A-G-V-K-K-G-R-K-Q-K-P-A-L-D-Q-V-A-A-Q-A-I-L-A-G-W-F-E-Q-P-G-T-A-V"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-S-E-S-V-R-I-V-A-C-P-T-C-K-A-E-V-R-W-E-P-Q-S-R-Y-R-P-F-C-S-E-R-C-R-L-I-D-L-G-Q-W-A-S-E-S-Y-R-V-P-A-E-E-D-H-P-P-G-E-T-P-P-T-H"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-I-S-K-Y-N-R-P-M-E-N-L-S-N-L-D-Y-S-S-Y-L-K-G-W-I-R-T-V-P-N-W-P-Q-Q-G-V-M-F-R-D-I-T-P-L-L-Q-N-P-K-T-F-R-M-L-I-D-I-Y-V-H-R-Y-M-M-E-K-V-D-L-V-A-G-L-D-A-R-G-F-I-I-G-S-V-L-A-Y-E-L-N-V-G-F-V-P-I-R-K-K-G-K-L-P-F-T-T-V-E-E-E-Y-E-L-E-Y-G-N-A-A-V-E-M-H-T-D-A-C-K-P-G-D-R-V-I-L-I-D-D-L-V-A-T-G-G-T-M-M-A-G-Y-K-L-L-K-R-M-G-A-D-V-L-E-A-A-A-I-I-E-L-P-E-L-G-G-G-Q-L-V-R-D-G-G-L-D-L-F-T-V-C-S-Y-E-G-H"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-V-D-D-C-L-D-R-I-Q-N-R-F-D-L-T-L-A-A-A-Y-R-A-R-Q-V-A-S-G-A-S-A-F-V-E-P-G-R-H-K-P-T-V-I-A-L-R-E-I-A-A-G-H-V-G-K-E-V-L-N-R-G-K-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-S-A-Q-A-R-K-R-A-R-T-A-L-K-Q-R-A-H-N-A-S-L-R-T-A-F-R-T-A-V-K-K-V-L-K-A-I-E-A-G-D-K-A-A-A-R-V-V-F-Q-A-S-E-K-V-I-D-R-I-A-D-K-G-V-F-H-K-N-K-A-A-R-H-K-S-R-L-S-A-Q-I-K-A-M-A"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-S-A-K-A-H-E-V-K-R-E-W-Y-V-V-D-A-A-D-K-V-L-G-R-L-A-A-E-I-A-R-R-L-R-G-K-H-K-P-E-F-T-P-H-V-D-T-G-D-F-I-V-V-V-N-V-E-K-L-R-V-T-G-T-K-A-Q-D-K-K-Y-Y-R-H-S-G-Y-P-G-G-I-Y-E-R-T-F-T-E-L-Q-N-Q-F-P-E-R-V-L-E-K-A-V-K-G-M-L-P-K-G-P-L-G-Y-A-M-I-K-K-L-K-V-Y-S-G-S-E-H-P-H-A-A-Q-Q-P-K-V-L-E-I"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters ### SEQUENCE -M-T-E-A-A-T-E-M-P-S-P-I-N-F-T-E-S-A-C-A-K-V-Q-D-L-I-A-E-E-G-N-P-D-L-K-L-R-V-F-V-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-I-A-N-E-D-D-T-A-I-E-R-Q-G-V-T-F-L-V-D-P-M-S-Y-Q-Y-L-V-G-A-E-I-D-Y-Q-E-S-L-E-G-S-Q-F-V-I-R-N-P-N-A-T-T-T-C-G-C-G-S-S-F-S-V"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-R-D-E-D-L-V-V-M-G-F-V-R-G-A-F-G-I-K-G-W-V-K-I-H-A-D-T-E-Y-A-D-G-L-F-D-Y-P-T-W-W-L-G-K-N-G-S-W-K-P-Y-A-F-E-N-G-A-V-Q-P-K-A-L-A-A-K-L-E-G-V-D-D-R-D-A-A-E-A-L-R-G-T-Q-I-A-I-P-R-S-E-L-P-E-A-G-D-G-E-Y-Y-W-A-D-L-I-G-L-S-V-V-N-Q-Q-G-E-T-L-G-K-V-D-S-L-L-E-T-G-A-N-D-V-L-V-V-K-G-G-D-G-Q-Q-R-L-I-P-F-V-D-Q-Y-V-L-E-V-V-P-A-E-G-R-I-L-V-D-W-G-L-D-Y"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-D-L-I-Q-K-L-E-Q-E-E-I-A-R-L-G-K-T-L-P-E-F-A-P-G-D-T-V-V-V-Q-V-K-V-K-E-G-N-R-E-R-L-Q-A-Y-E-G-V-V-I-A-K-R-N-R-G-L-N-S-A-F-T-V-R-K-M-S-A-G-E-G-V-E-R-T-F-Q-T-Y-S-P-L-V-A-S-V-E-V-K-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-G-R-T-G-K-S-A-R-I-K-E-K-L-P-A-R-K-Q-G"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-K-V-D-M-S-T-S-V-K-D-D-A-Q-L-E-A-S-R-V-R-E-N-P-P-P-M-Y-K-V-L-L-L-N-D-D-F-T-P-M-D-F-V-V-Q-V-L-Q-Q-F-F-H-M-N-R-E-K-A-T-H-I-M-L-Q-V-H-T-Q-G-H-G-V-C-G-V-Y-T-K-D-V-A-A-T-K-V-E-Q-V-L-Q-Y-A-K-A-H-Q-H-P-L-Q-C-V-M-E-E-N"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-I-V-H-P-D-Q-S-E-Q-V-P-A-M-I-E-R-Y-K-G-M-V-L-A-A-E-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-Q-K-L-H-K-A-H-Y-V-L-M-N-V-E-C-Q-A-E-T-L-A-E-I-E-H-A-F-K-F-N-D-A-V-L-R-H-L-T-I-K-M-D-R-A-I-S-D-A-S-P-M-M-K-D-E-K-A-K-N-L-L-D-A-Q-P-A-A-E-V-E-A-S-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-Q-L-F-K-R-K-K-F-C-R-F-T-A-E-G-I-K-E-I-D-Y-K-S-V-D-L-L-K-D-F-I-A-E-N-G-K-I-I-P-A-R-I-T-G-T-K-A-R-Y-Q-R-Q-L-T-T-A-I-K-R-A-R-F-L-A-F-L-P-Y-T-D-Q-H"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-E-K-V-A-N-L-G-Q-L-G-D-V-V-N-V-K-N-G-F-A-R-N-F-L-I-P-Q-G-K-A-K-R-A-T-E-A-N-L-K-E-F-D-A-R-R-A-E-L-E-A-K-Q-A-E-I-L-A-D-A-K-V-R-A-E-K-L-N-E-A-V-I-T-I-A-Q-K-A-G-V-D-G-R-L-F-G-S-V-T-N-V-D-V-A-E-A-V-T-A-F-G-V-Q-I-K-R-H-E-V-R-L-P-N-G-P-F-K-A-I-G-E-Y-D-I-E-I-A-L-H-H-D-V-V-T-P-I-K-I-V-V-V-G-E-A"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-S-S-K-G-Q-M-L-Q-D-P-F-L-N-I-L-R-K-E-H-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-V-E-S-F-D-Q-Y-V-V-L-L-K-N-T-V-T-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-P-V-N-I-P-H-E-H-P-A-Q-K-Q-E-Q-A-Q-D-A"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-I-I-Q-N-R-K-A-F-H-D-Y-F-I-E-E-K-L-E-A-G-L-V-L-E-G-W-E-V-K-A-I-R-A-G-R-V-Q-L-K-E-S-Y-V-D-W-K-N-G-A-F-W-L-I-G-C-H-I-T-P-L-Q-S-A-S-T-H-V-K-P-D-P-V-R-P-R-K-L-L-M-S-Q-A-E-I-N-R-F-I-G-K-V-E-R-A-G-Y-T-M-M-A-L-D-L-H-Y-T-K-G-N-V-K-A-E-V-G-L-A-K-G-K-K-L-H-D-K-R-D-T-E-K-D-R-E-W-Q-R-E-K-Q-R-V-M-K-N-Q-R-G-A-A"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-W-L-T-V-T-L-V-T-V-I-L-A-L-Q-W-P-L-W-F-G-K-G-S-W-L-R-V-W-Q-L-D-K-Q-L-Q-E-Q-R-A-T-T-Q-K-L-V-A-R-N-A-A-L-D-A-E-V-R-D-L-K-Q-G-S-D-A-I-E-E-R-A-R-N-E-L-G-M-I-R-N-G-E-V-F-F-Q-L-L-D-P-S-K-N-P-S-R-A-S-H-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-I-P-A-E-L-K-Y-V-D-S-H-E-W-L-R-L-E-A-D-G-S-V-T-V-G-I-T-A-H-A-Q-E-L-L-G-D-I-V-F-V-E-L-P-K-V-G-A-S-L-A-K-D-E-Q-A-G-V-V-E-S-V-K-A-A-S-D-V-Y-C-P-I-A-G-E-V-L-A-V-N-E-E-L-E-G-E-P-E-L-A-N-S-D-P-Y-G-D-G-W-F-F-K-I-K-P-A-N-A-A-D-L-N-G-L-M-D-A-A-A-Y-A-K-E-I-G-A"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-H-I-V-L-A-S-T-S-R-Y-R-Q-E-I-I-A-R-L-G-L-P-F-C-A-E-P-P-V-C-D-E-T-P-L-P-G-E-T-A-L-E-T-A-V-R-L-A-R-V-K-A-Q-S-L-A-G-K-H-P-E-A-L-I-I-G-S-D-Q-V-A-L-L-D-D-K-Q-I-G-K-P-G-G-F-E-Q-G-V-E-M-L-K-W-M-S-G-R-T-V-V-F-H-S-A-L-A-L-Y-N-T-A-S-G-R-L-Q-E-C-V-G-I-T-R-V-T-L-R-R-L-T-E-A-Q-I-R-N-Y-L-T-R-E-P-D-A-L-H-C-A-G-S-A-K-S-E-G-L-G-G-A-L-L-E-K-V-E-S-D-D-P-N-A-L-I-G-V-P-L-F-Q-L-I-T-M-L-G-N-E-G-V-E-V-L-K"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-I-D-M-I-F-G-K-R-Q-K-S-A-A-I-A-R-E-R-L-Q-I-I-L-A-H-E-R-N-G-R-H-A-P-D-Y-L-P-A-L-Q-R-E-L-M-E-V-I-S-K-Y-V-S-V-N-L-E-D-I-K-V-Q-V-E-R-Q-D-D-Y-E-V-L-E-V-N-I-V-L-P-E-H-Q-R"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-G-L-N-I-T-N-R-Q-G-F-L-L-V-A-A-A-C-A-G-A-I-G-F-A-L-F-A-Q-Y-Q-L-G-E-E-P-C-P-L-C-I-L-Q-R-I-G-V-M-A-V-G-A-L-A-L-L-A-A-L-H-N-P-G-K-T-G-A-K-V-W-G-G-L-M-T-L-A-A-L-S-G-A-G-V-S-L-R-Q-L-W-L-Q-S-L-P-A-D-Q-V-P-Q-C-G-P-G-L-E-F-L-M-E-S-F-P-L-W-E-V-L-S-K-V-L-K-G-S-G-E-C-A-A-I-Q-G-R-F-L-G-M-T-M-P-F-W-V-A-V-F-F-A-G-V-I-V-W-T-L-W-L-V-G-R-R-R-R-G"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-A-R-L-S-E-R-L-A-E-R-N-S-Q-L-V-Y-K-D-A-E-L-A-V-K-T-I-L-D-A-M-A-N-N-L-A-Q-G-S-R-I-E-I-R-G-F-G-S-F-D-L-N-Y-R-P-P-R-V-G-R-N-P-K-S-G-A-S-V-S-V-P-E-K-Y-V-P-H-F-K-A-G-K-E-L-R-E-R-V-D-L-S-L-L-E-Q-T-Q-A"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-F-F-T-D-L-L-P-V-L-L-F-F-G-A-Y-W-L-T-R-D-M-F-V-A-T-G-V-A-I-A-A-T-A-V-M-V-A-W-A-W-F-K-H-R-K-V-D-T-M-Q-W-I-S-L-G-L-I-V-V-L-G-G-A-T-L-L-L-H-D-K-H-F-I-M-W-K-P-T-V-L-Y-W-V-M-G-A-G-L-L-I-S-E-F-A-G-K-N-G-L-R-L-M-M-G-K-Q-I-E-M-P-D-P-V-W-R-K-L-T-W-A-W-S-G-F-F-A-F-M-G-A-L-N-L-F-V-A-Y-H-F-S-E-D-V-W-V-N-F-K-L-F-G-G-M-G-L-M-L-L-F-V-I-A-Q-S-L-F-L-A-K-Y-I-E-E-K-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-K-A-A-K-A-P-A-S-F-E-T-A-L-A-Q-L-E-D-I-I-Q-A-M-D-S-G-D-M-P-L-E-T-A-L-A-S-Y-K-Q-G-T-E-L-I-K-F-C-Q-G-K-L-A-D-A-E-Q-Q-L-K-I-L-E-N-N-E-L-K-T-L-D-L-P-N-G-Q"} +{"text": "### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate May function as an ADP-ribosylase ### SEQUENCE -M-I-A-R-N-P-I-K-Q-D-P-A-M-R-N-T-Q-D-D-H-S-R-F-L-S-L-V-L-R-H-Q-P-E-T-I-G-L-Q-L-D-D-Q-G-W-A-D-I-G-E-L-L-A-R-L-A-A-K-G-R-N-L-G-R-K-Q-L-E-K-I-V-L-D-N-D-K-Q-R-F-A-I-S-E-D-G-L-R-I-R-A-N-Q-G-H-S-I-K-I-D-L-G-L-A-A-C-E-P-P-D-R-L-Y-H-G-T-A-S-R-F-L-D-A-I-L-A-E-G-L-R-P-G-Q-R-Q-H-V-H-L-S-A-D-G-Q-T-A-R-K-V-G-A-R-H-G-K-P-V-V-L-E-I-D-A-R-A-M-R-Q-A-G-L-A-F-Y-R-S-D-N-G-V-W-L-I-D-G-V-P-P-V-F-I-R-Q-T-E-A-R"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-T-A-R-R-R-A-R-E-F-A-V-Q-G-I-Y-E-W-E-L-N-P-D-R-P-A-S-L-I-E-K-H-L-R-E-N-E-Y-F-A-K-A-D-E-A-L-F-R-S-I-L-Y-G-V-L-K-D-V-E-L-L-S-A-Q-V-G-R-Y-Y-E-R-A-E-D-E-V-S-P-V-E-R-A-V-L-L-M-A-A-L-E-L-T-Q-S-P-E-T-P-Y-P-V-I-I-N-E-A-I-E-I-T-K-T-F-G-G-T-D-G-H-K-F-V-N-G-V-L-D-K-L-A-A-E-V-R-G-D-E-V-L-A-Q-K-Q-R-R-K-Q-D"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-L-D-A-I-Q-C-I-E-P-N-F-S-G-K-G-L-K-I-G-I-A-M-A-R-F-N-T-P-V-C-H-G-L-R-D-A-C-L-A-E-L-E-K-L-G-V-A-A-G-D-I-T-L-A-T-V-P-G-A-L-E-V-P-L-V-L-Q-T-M-A-K-S-G-R-F-D-A-L-V-A-L-G-A-V-I-R-G-E-T-Y-H-F-E-L-V-S-N-E-S-G-A-G-V-T-R-V-G-L-D-F-D-I-P-V-A-N-A-I-L-T-T-E-N-D-E-Q-A-E-V-R-M-L-E-K-G-G-D-A-A-R-V-A-V-E-M-A-N-L-H-K-T-L-R-G"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-Q-D-T-N-N-L-I-W-L-D-M-E-M-T-G-L-N-P-D-Q-D-R-I-I-E-V-A-M-I-V-T-D-S-N-L-N-V-L-A-E-S-P-V-L-V-I-H-Q-P-D-A-I-L-D-G-M-D-D-W-N-K-N-T-H-G-K-S-G-L-I-E-K-V-K-N-S-T-V-S-E-A-E-A-E-Q-L-L-L-E-F-M-M-Q-H-V-P-E-R-A-T-P-M-C-G-N-T-I-H-Q-D-R-R-F-M-A-R-W-M-P-K-L-E-A-Y-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-C-K-R-W-R-P-E-I-A-K-G-V-V-K-R-G-K-H-E-A-L-A-D-I-L-E-S-I-E-E-M-R-Y-Y-R-E-H-F-L-K-V"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-K-A-I-L-G-G-G-C-F-W-C-L-E-A-A-F-S-Q-L-K-G-V-E-R-V-V-S-G-Y-C-G-G-H-T-D-S-P-D-Y-R-Q-V-C-S-G-D-S-G-H-V-E-V-V-E-I-S-Y-D-P-A-L-I-D-Y-A-T-L-L-Q-V-F-F-A-V-H-D-P-T-T-L-N-R-Q-G-H-D-V-G-T-Q-Y-A-S-A-I-F-Y-L-D-E-T-Q-R-E-C-A-R-R-V-I-A-Q-L-D-A-E-Q-I-F-D-A-P-I-V-T-R-V-E-S-A-P-R-F-H-P-A-E-D-Y-H-Q-N-Y-Y-A-Q-N-Q-Q-Q-N-Y-C-Q-L-V-I-S-P-K-L-A-K-I-R-R-R-F-S-H-L-L-Q-N"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-E-I-K-K-S-A-E-Q-K-M-Q-K-T-L-E-A-F-K-N-D-L-A-K-V-R-T-G-R-A-H-T-G-I-L-D-H-V-M-V-D-Y-Y-G-S-D-V-P-V-N-Q-V-A-N-V-T-L-I-D-A-R-T-I-G-V-Q-P-W-E-K-P-M-L-A-K-I-E-K-A-I-R-D-S-D-L-G-L-N-P-A-S-M-G-E-I-I-R-V-P-M-P-M-L-T-E-E-R-R-K-D-L-I-K-V-V-R-G-E-A-E-G-A-R-V-A-V-R-N-I-R-R-D-S-N-T-E-F-K-N-L-L-K-D-K-A-I-T-E-D-D-E-R-R-G-Q-D-E-I-Q-K-L-T-D-K-Y-T-A-E-I-D-K-M-L-A-T-K-E-A-D-L-L-A-V"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-Y-G-I-G-T-D-L-V-E-I-A-R-M-E-A-W-C-R-R-W-G-E-K-A-G-R-R-L-L-T-A-A-E-Q-A-E-F-A-A-H-A-E-P-A-R-F-L-A-K-R-F-A-A-K-E-A-F-A-K-A-L-G-T-G-V-V-A-P-A-L-L-T-A-I-G-V-G-H-D-E-L-G-K-P-V-L-I-L-S-D-E-L-A-A-F-A-A-A-R-G-I-A-R-M-H-L-S-I-S-D-E-R-G-H-A-L-A-F-V-V-L-E-S"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-R-F-D-S-N-Q-L-G-N-V-E-V-D-E-T-T-I-I-T-F-P-Q-G-I-P-A-L-E-N-C-T-R-F-K-L-F-H-D-I-T-Q-P-T-P-Q-M-Y-W-L-Q-S-L-D-D-P-G-I-T-F-S-L-A-L-P-D-R-L-G-V-R-F-Q-I-E-L-S-D-E-E-V-A-Q-L-Q-L-S-G-P-Q-D-A-A-I-L-L-M-L-Y-R-P-L-D-L-D-R-D-S-H-P-V-L-G-A-L-Q-A-N-L-C-N-P-L-V-I-S-L-S-S-R-R-G-I-Q-K-T-G-L-K-I-D-I-L-L-H-T-P"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-W-K-S-I-L-A-I-A-I-G-A-A-A-G-A-L-L-R-W-F-L-G-L-R-L-N-S-L-F-P-S-L-P-P-G-T-L-A-A-N-L-V-G-G-Y-I-I-G-V-A-V-A-L-F-A-D-M-P-M-L-S-P-L-W-R-L-L-I-I-T-G-F-C-G-G-L-T-T-F-S-T-F-S-A-E-V-V-D-L-L-R-Q-G-Q-L-Q-P-A-F-A-A-I-A-V-H-V-S-G-S-L-L-M-T-M-A-G-I-A-S-W-Q-W-L-R-R"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-E-D-M-I-E-L-E-G-V-V-I-E-M-L-P-E-S-R-F-R-V-R-L-D-N-N-M-E-I-L-A-Y-G-S-G-K-M-K-M-H-R-I-R-V-L-L-G-D-R-V-T-V-E-M-S-P-Y-D-L-T-K-G-R-I-N-F-R-H-P-T-A-N-P-G-A-G-P-R-P-S-H-H-H-R-R"} +{"text": "### FUNCTION Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide ### SEQUENCE -M-Q-S-Q-C-Q-P-A-P-R-Q-A-L-T-D-A-V-I-A-A-K-A-R-K-R-L-S-F-E-D-I-N-Q-G-T-G-L-S-L-A-Y-T-T-A-A-L-L-G-Q-H-A-L-P-E-A-A-A-R-L-V-A-E-R-L-E-L-D-E-D-A-I-A-L-L-Q-A-I-P-L-R-G-S-I-P-G-G-V-P-T-D-P-T-I-Y-R-F-Y-E-M-V-Q-I-Y-G-T-T-L-K-A-L-V-H-E-Q-F-G-D-G-I-I-S-A-I-N-F-K-L-D-I-R-K-V-E-D-P-D-G-G-H-R-A-V-I-T-L-D-G-K-Y-L-P-T-K-P-F"} +{"text": "### FUNCTION Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate ### SEQUENCE -M-A-D-K-T-G-T-L-W-Y-V-M-G-P-S-G-A-G-K-D-S-L-L-A-Y-A-R-Q-R-L-P-G-G-V-M-F-A-H-R-Y-I-T-R-P-A-D-A-G-G-E-N-H-V-A-L-S-R-E-E-F-D-A-R-E-A-G-G-C-F-A-L-V-W-R-R-H-G-L-A-Y-G-L-G-V-E-T-E-L-W-L-G-Q-G-M-D-V-V-V-N-G-S-R-S-S-L-P-L-A-M-A-R-F-P-T-L-R-P-L-W-I-T-A-S-P-E-V-L-A-V-R-L-R-Q-R-A-R-E-C-G-E-V-I-E-R-R-L-A-E-A-A-S-F-A-P-P-A-G-C-E-V-L-V-N-D-G-A-L-A-Q-A-G-D-T-L-L-R-W-L-R-G-G-R-R-V-C"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-N-D-I-H-P-N-Y-K-E-L-S-V-T-C-S-C-G-Q-Q-F-V-T-K-S-T-M-G-K-D-A-F-S-I-E-V-C-S-S-C-H-P-F-Y-T-G-K-Q-K-I-V-D-T-A-G-R-V-D-K-F-N-Q-K-F-G-S-F-F-K-R"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-Q-F-R-G-N-V-M-Q-E-N-Q-N-Q-A-A-E-A-V-E-N-E-M-T-E-T-A-S-A-A-H-T-E-L-E-Q-T-P-E-Q-R-I-A-G-L-E-A-E-I-A-E-L-N-D-T-L-L-R-A-R-A-E-L-E-N-Q-R-R-R-A-Q-D-E-V-A-A-A-H-K-Y-A-I-G-K-F-A-A-E-L-V-T-V-K-D-Y-L-E-M-A-L-L-D-Q-S-G-Q-I-D-A-L-K-M-G-V-D-M-T-L-K-Q-L-V-S-A-F-D-K-A-Q-I-K-D-I-A-P-K-L-G-D-K-L-D-P-H-Q-H-Q-A-M-S-A-E-E-S-D-A-E-P-N-T-V-V-R-V-M-Q-K-G-Y-L-L-A-D-R-V-L-R-P-A-M-V-V-V-A-K-A-K-A"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-K-N-P-P-A-L-E-Q-L-I-S-A-L-K-V-L-P-G-V-G-P-K-T-A-Q-R-M-A-F-H-L-L-Q-R-D-K-Q-G-A-D-K-L-A-R-A-L-D-R-A-L-T-Q-L-T-H-C-Q-R-C-N-T-F-S-E-A-E-L-C-A-I-C-A-D-E-T-R-R-R-D-Q-L-C-I-V-E-M-P-A-D-L-M-M-L-E-Q-A-K-C-F-D-G-L-Y-F-V-L-M-G-R-I-S-P-L-D-N-I-G-P-K-D-L-H-L-D-K-L-L-A-R-A-L-D-G-Q-V-S-E-I-V-I-A-T-N-F-T-A-E-G-E-V-T-S-H-M-L-S-E-L-F-K-E-R-G-L-T-V-T-R-I-A-R-G-M-P-V-G-G-E-L-E-Y-V-D-L-G-T-L-A-Q-A-V-Y-E-R-R-G-V"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-A-G-I-A-G-L-M-K-Q-A-Q-Q-M-Q-E-N-M-K-K-A-Q-E-E-L-A-K-V-E-V-E-G-Q-S-G-A-G-M-V-K-V-T-M-T-C-S-H-D-V-K-R-V-A-I-D-D-S-V-L-E-D-A-K-E-D-K-E-M-L-E-D-L-I-A-A-A-F-N-D-A-V-R-K-V-E-A-T-T-Q-E-R-M-S-G-F-T-N-G-L-N-L-P-A-G-M-K-F-P-F"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-A-A-E-G-K-S-L-K-A-R-A-A-E-L-L-S-R-R-E-Y-T-R-Q-E-L-V-R-R-L-A-P-F-A-D-S-E-D-E-L-N-A-A-L-D-E-L-A-A-S-N-W-Q-S-D-D-R-F-A-R-Q-F-A-S-S-K-G-T-K-F-G-S-R-R-L-A-Q-E-M-R-Q-R-G-V-D-S-D-T-I-R-E-A-L-S-G-Q-D-D-L-A-S-A-R-E-Q-W-R-K-K-F-G-R-L-P-A-D-A-A-E-K-A-R-Q-Y-R-F-L-A-Q-R-G-F-P-A-D-V-I-R-Q-V-L-A-G-G-A-D-D-D-F-Y-E-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-M-T-A-A-Q-K-A-E-I-V-K-G-F-Q-R-A-E-G-D-T-G-S-S-E-V-Q-I-A-L-L-T-A-R-I-N-D-L-T-P-H-F-K-A-N-T-K-D-H-H-S-R-R-G-L-L-K-L-V-S-R-R-R-R-L-L-D-Y-L-K-R-T-D-A-E-G-Y-R-A-L-I-T-R-L-G-L-R-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-A-K-K-G-F-S-R-S-D-R-V-A-E-Q-I-Q-R-E-L-A-E-L-T-R-K-G-L-K-D-P-R-A-G-W-I-T-I-T-A-V-E-V-T-R-D-Y-S-H-A-K-V-Y-Y-T-V-M-V-D-S-T-R-E-A-T-Q-E-A-L-D-S-S-A-G-Y-L-R-N-E-L-G-R-A-I-K-M-F-S-M-P-Q-L-H-F-V-Y-D-D-S-V-E-R-G-M-H-L-T-S-L-I-N-Q-V-A-R-E-D-A-E-K-F-G-E-A-A-A-G-E-A-E-G-E-G-K-A-E"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-D-V-R-L-L-L-E-N-T-L-P-G-L-G-Y-E-L-V-D-F-E-M-T-P-G-G-G-F-R-V-F-I-D-K-P-G-G-I-T-V-E-D-C-V-L-V-S-N-H-F-T-R-L-F-M-V-E-N-V-D-Y-E-R-L-E-V-S-S-P-G-L-D-R-P-L-K-K-E-A-D-F-V-R-F-S-G-Q-L-A-K-I-K-T-R-M-P-I-E-Q-Q-K-K-F-T-G-R-L-A-G-V-E-D-G-S-V-K-L-D-V-D-G-R-I-V-E-I-P-F-A-N-I-D-K-A-R-L-E-P-E-F"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-T-A-Q-E-L-R-A-G-N-V-F-M-V-G-S-D-P-M-V-V-Q-K-A-E-F-S-K-S-G-R-N-A-S-V-V-K-M-K-M-K-N-L-L-T-G-A-G-S-E-A-V-Y-R-A-D-D-K-F-D-V-V-V-L-D-R-K-D-C-T-Y-S-Y-F-A-D-P-M-Y-V-F-M-D-T-E-F-N-Q-Y-E-V-E-A-D-N-L-G-D-T-I-N-Y-I-V-D-G-M-E-D-V-C-Q-V-T-F-Y-D-G-K-A-I-S-V-E-L-P-T-T-V-I-R-E-V-E-Y-T-E-P-A-V-R-G-D-T-S-G-K-V-L-K-P-A-R-L-V-G-T-T-F-E-V-Q-V-P-A-F-V-N-T-G-E-K-I-E-I-D-T-R-T-N-E-F-K-K-R-A"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-V-L-K-E-F-K-E-F-A-V-K-G-N-V-I-D-L-A-V-G-V-V-I-G-G-A-F-G-S-I-V-K-S-L-V-D-D-V-I-M-P-P-I-G-L-L-I-G-N-V-D-F-S-N-L-F-F-V-L-K-D-G-A-K-Q-A-G-P-Y-V-S-V-A-A-A-K-Q-A-G-A-T-T-L-N-L-G-L-F-I-N-A-L-V-S-F-T-I-V-A-F-A-I-F-M-L-V-K-A-I-N-R-L-K-R-E-E-A-A-P-A-P-A-A-P-A-T-K-E-C-R-Y-C-L-S-A-I-P-E-K-A-T-R-C-P-C-C-T-S-Q-L-D"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-L-T-K-A-E-L-A-D-L-L-F-D-Q-V-G-L-N-K-R-E-A-K-D-M-V-E-S-F-F-E-E-I-R-L-A-L-E-S-G-D-S-V-K-L-S-G-F-G-N-F-Q-L-R-D-K-P-Q-R-P-G-R-N-P-K-T-G-E-E-I-P-I-T-A-R-R-V-V-T-F-H-A-S-Q-K-L-K-G-M-V-E-Q-Y-H-A-N-K-Q-G"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-R-A-R-H-K-K-I-L-A-L-A-K-G-Y-R-G-R-R-K-N-V-Y-R-I-A-K-Q-A-V-M-K-A-G-Q-Y-A-Y-R-D-R-R-Q-K-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-A-R-E-N-G-L-P-Y-S-K-F-M-N-G-L-K-K-A-A-I-E-I-D-R-K-V-L-A-D-L-A-V-F-D-K-P-A-F-A-Q-I-V-E-K-A-K-A-S-L-A-A"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-A-I-A-Q-E-R-E-A-R-I-N-G-E-I-T-A-R-E-I-R-L-V-G-K-E-G-E-Q-I-G-I-V-S-L-R-E-A-M-A-L-A-E-E-N-D-V-D-L-V-E-I-S-P-T-A-Q-P-P-V-C-K-L-M-D-Y-G-K-Y-K-Y-E-Q-S-K-K-R-H-E-A-K-Q-K-Q-K-Q-V-Q-I-K-E-I-K-F-R-P-G-T-D-D-G-D-Y-N-V-K-L-R-N-L-V-R-F-L-T-E-G-D-K-A-K-V-T-L-R-F-R-G-R-E-M-A-H-Q-D-I-G-L-A-L-L-K-R-V-E-A-D-L-A-E-V-G-T-V-E-Q-F-P-R-L-E-G-R-Q-M-V-M-M-I-A-P-K-K-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-A-F-C-G-N-P-D-T-Q-V-I-D-S-R-V-S-E-D-G-S-S-I-R-R-R-R-R-C-P-A-C-D-K-R-F-T-T-F-E-T-A-D-V-R-M-P-Q-V-V-K-T-A-G-H-R-S-E-F-D-I-E-K-V-R-T-S-F-L-R-A-L-H-K-R-P-V-S-T-T-L-V-D-E-A-I-D-R-I-C-H-K-L-L-Q-L-G-E-R-E-V-S-S-R-Q-I-G-E-M-V-M-N-E-L-A-R-L-D-K-V-A-Y-V-R-F-A-S-V-Y-R-S-F-Q-D-I-S-E-F-T-D-A-I-K-E-I-Q-K-S-S-H"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-E-Q-Q-E-L-Q-P-A-F-S-I-E-K-I-Y-V-K-D-I-S-L-E-V-P-N-A-P-Q-V-F-L-E-Q-A-Q-P-E-I-D-M-Q-L-A-S-A-G-Q-Q-L-D-D-G-F-F-E-V-T-L-T-V-T-V-T-A-K-L-P-E-K-T-M-F-L-C-E-V-A-Q-A-G-I-F-Q-I-R-N-I-P-G-E-D-L-D-P-I-L-G-V-A-C-P-N-I-L-F-P-Y-A-R-E-T-V-S-S-V-V-N-R-A-G-F-P-P-V-L-L-A-P-I-N-F-E-A-L-Y-M-Q-Q-R-A-Q-Q-A-E-A-G-N-A"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-L-D-R-D-G-Y-R-P-N-V-G-I-I-L-T-N-A-K-N-E-V-F-W-G-K-R-V-R-E-H-S-W-Q-F-P-Q-G-G-I-K-P-G-E-S-P-E-A-A-M-Y-R-E-L-L-E-E-V-G-L-L-P-Q-H-V-K-I-L-G-R-T-R-D-W-L-R-Y-E-V-P-T-N-W-V-R-R-E-W-R-G-S-Y-K-G-Q-K-Q-I-W-F-L-L-R-L-V-G-R-D-S-D-V-C-L-R-A-T-N-H-P-E-F-D-G-W-R-W-N-D-Y-W-A-P-V-D-A-V-I-E-F-K-R-D-V-Y-E-R-A-L-S-E-L-A-R-F-M-R-G-V-E-S-H-H-A-Y-L-A-R-T-S-T-Q-S-E-Q"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-H-D-F-N-Q-D-F-F-S-L-F-G-L-P-R-R-F-A-I-D-A-A-G-L-D-A-A-W-R-A-A-A-A-Q-V-H-P-D-R-Y-A-A-S-S-D-A-D-K-R-S-A-L-M-L-A-T-R-V-N-E-G-Y-Q-T-L-K-S-P-L-N-R-A-R-Y-L-L-Q-L-S-G-V-D-T-Q-E-E-N-N-T-R-M-P-A-D-F-L-M-A-Q-M-E-W-R-E-S-I-D-D-A-R-A-D-V-D-A-L-E-S-L-S-R-R-L-R-G-E-V-R-D-L-Q-T-E-L-E-A-A-L-D-A-R-A-D-L-D-A-A-A-V-L-V-R-K-L-R-F-M-E-K-L-D-Q-E-I-G-D-A-I-E-S-L-L-D"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-P-H-T-P-P-A-Y-P-A-A-S-A-D-H-R-P-P-S-S-P-P-A-E-P-A-G-E-A-V-F-L-H-P-G-D-W-H-F-G-D-S-Q-T-R-I-R-T-L-L-G-S-C-V-S-I-T-L-W-H-P-Q-A-K-V-G-G-M-C-H-Y-L-L-A-Q-R-T-P-H-R-G-E-S-L-S-G-R-Y-G-D-E-A-M-L-L-L-L-R-E-I-L-D-T-G-L-P-L-Q-E-F-Q-A-R-L-I-G-G-A-S-M-L-L-S-R-E-R-K-L-S-H-D-V-P-S-R-N-I-Q-Q-A-R-L-M-V-K-Q-L-G-L-K-L-L-A-E-D-L-G-G-N-C-P-R-M-V-L-F-D-V-A-S-G-N-V-W-I-K-Q-S-Q-E-A-E-L-E-Q-A-P-H-T-R-T-R-K"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur , and thus conserves the redox energy in a proton gradient ### SEQUENCE -M-A-S-K-K-M-E-A-L-G-S-V-V-A-E-A-L-G-D-K-L-V-R-S-T-L-A-L-D-E-L-T-I-V-C-K-A-S-D-L-L-S-V-A-Q-T-L-R-D-H-A-D-L-A-F-E-Q-C-I-D-V-C-G-M-D-Y-S-A-Y-R-D-E-P-W-D-G-P-R-F-A-A-V-Y-H-L-L-S-V-K-L-N-H-R-I-R-L-R-V-F-A-E-D-D-D-F-P-V-I-P-S-V-N-G-I-W-N-A-A-N-W-F-E-R-E-A-F-D-L-Y-G-I-V-F-E-G-H-P-D-L-R-R-L-L-T-D-Y-G-F-V-G-H-P-F-R-K-D-F-P-L-S-G-Y-V-E-M-R-Y-D-P-T-Q-Q-R-V-I-Y-Q-P-V-T-I-E-P-R-E-I-T-P-R-I-I-R-E-E-N-Y-G-G"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-K-T-G-G-K-Q-Y-K-V-A-I-G-E-K-L-K-V-E-Q-I-P-A-D-V-D-S-Q-I-V-L-E-E-V-L-M-I-A-D-G-E-Q-V-V-V-G-A-P-L-V-S-G-A-T-V-K-A-T-V-V-S-H-G-R-G-E-K-I-R-I-F-K-M-R-R-R-K-H-Y-Q-K-H-Q-G-H-R-Q-N-Y-T-E-I-R-I-D-A-I-S-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-K-M-R-V-E-V-V-S-T-E-Q-L-I-F-S-G-E-A-E-F-V-V-A-P-A-T-E-G-E-I-G-V-Y-P-Q-H-V-P-L-L-T-R-I-K-P-G-V-L-R-L-K-V-P-G-T-K-E-E-V-L-V-A-V-S-G-G-M-M-E-V-Q-P-S-L-I-T-V-L-A-D-T-A-I-R-G-E-D-L-D-E-A-R-A-N-E-A-K-R-A-A-E-D-A-L-K-H-A-T-D-D-M-S-T-A-K-A-H-A-A-L-A-V-A-I-A-E-L-K-T-L-D-Y-L-K-K-R-A-H"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-L-I-T-V-A-R-P-Y-A-E-A-V-Y-S-L-A-T-E-Q-G-K-L-D-Q-W-S-D-A-L-S-W-L-A-A-M-V-N-N-P-D-L-A-Q-V-V-T-N-P-K-H-T-A-Q-E-V-E-A-L-M-L-D-V-L-G-S-R-G-N-D-D-V-K-R-F-I-A-A-L-I-E-N-A-R-L-T-L-L-P-E-I-A-A-Q-F-E-L-L-K-A-Q-S-E-N-I-V-D-A-L-V-E-S-A-F-A-L-S-D-E-Q-K-A-E-L-T-N-T-L-S-K-K-Y-G-K-A-V-R-L-D-V-R-E-N-A-D-L-I-G-G-V-R-V-S-V-G-D-D-V-I-D-A-S-V-R-G-K-L-Q-A-M-A-A-S-L-K-N"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-L-S-I-W-H-W-L-I-V-L-L-I-V-V-L-V-F-G-T-K-K-L-P-G-I-G-K-D-L-G-N-A-V-K-G-F-K-E-G-M-N-E-G-A-K-D-G-Q-P-P-A-K-D-A-G-R-I-I-D-G-E-A-D-K-K"} +{"text": "### FUNCTION Functions as a ribosomal silencing factor Interacts with ribosomal protein uL14 , blocking formation of intersubunit bridge B8 Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation ### SEQUENCE -M-E-I-Q-E-I-S-K-L-A-I-E-A-L-E-D-I-K-G-K-D-I-I-E-L-D-T-S-K-L-T-S-L-F-Q-R-M-I-V-A-T-G-D-S-N-R-Q-V-K-A-L-A-N-S-V-Q-V-K-L-K-E-A-G-V-D-I-V-G-S-E-G-H-E-S-G-E-W-V-L-V-D-A-G-D-V-V-V-H-V-M-L-P-A-V-R-D-Y-Y-D-I-E-A-L-W-G-G-Q-K-P-S-F-A-V-G-A-A-K-P-W-S-A-V"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-T-I-L-A-V-G-T-K-M-P-R-W-V-D-E-A-Y-T-D-Y-A-K-R-F-G-R-D-I-T-L-E-L-K-E-I-K-P-E-K-R-G-G-G-V-T-A-E-K-G-I-A-A-E-H-E-R-L-I-A-A-I-P-P-R-A-R-L-V-V-M-D-E-R-G-K-N-W-T-S-V-K-L-A-E-G-L-K-E-W-M-A-G-G-G-D-V-V-F-V-I-G-G-A-D-G-L-S-A-E-L-K-Q-R-A-D-V-L-L-Q-L-S-A-M-T-L-P-H-G-M-V-R-V-M-L-A-E-Q-I-Y-R-A-Y-S-I-L-N-N-H-P-Y-H-R-E"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-Q-Y-T-R-T-V-E-A-L-K-Q-G-T-V-I-D-H-I-P-A-G-E-G-V-K-I-L-R-L-F-K-L-T-E-T-G-E-R-V-T-V-G-L-N-L-V-S-R-H-M-G-S-K-D-L-I-K-V-E-N-V-A-L-T-E-E-Q-A-N-E-L-A-L-F-A-P-K-A-T-V-N-V-I-D-N-F-E-V-V-K-K-H-K-L-T-L-P-D-A-V-E-G-I-F-S-C-P-N-S-N-C-I-S-H-N-E-P-V-K-S-V-F-Y-V-K-T-L-A-H-D-T-K-M-K-C-K-Y-C-E-K-V-F-S-R-D-I-V-A-E-V-R"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-T-E-S-E-F-L-Q-L-S-D-D-I-F-D-R-I-E-Q-A-I-D-E-H-G-L-D-A-D-T-L-R-Q-G-N-V-L-E-I-E-F-D-S-G-D-K-V-I-V-N-R-H-A-V-N-Q-E-M-W-I-A-A-K-S-G-G-Y-H-F-S-R-R-G-E-A-W-I-A-S-R-D-G-A-E-F-Y-A-T-L-A-E-A-I-R-A-G-S-G-E-A-F-D-F-A-G"} +{"text": "### FUNCTION Putative transcription factor May function redundantly with odd and sob in leg joint formation during the larval stages, acting downstream of Notch activation ### SEQUENCE -M-F-A-V-M-R-I-D-N-D-D-R-R-A-D-F-R-R-K-M-R-P-K-C-E-F-V-C-K-Y-C-Q-R-R-F-T-K-P-Y-N-L-M-I-H-E-R-T-H-K-S-P-E-V-T-F-S-C-E-V-C-G-K-Y-F-K-R-Q-D-N-L-R-S-H-R-C-S-Q-C-I-W-R"} +{"text": "### FUNCTION E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage ### SEQUENCE -M-V-D-D-G-T-R-K-A-L-S-G-I-P-L-L-K-T-K-A-G-P-R-D-K-E-L-W-V-Q-R-L-K-E-E-Y-Q-A-L-I-K-Y-V-Q-N-N-K-A-S-D-M-D-W-F-R-L-E-S-N-K-E-G-T-K-W-F-G-K-C-W-Y-M-Y-N-L-H-K-Y-E-F-D-V-E-F-D-I-P-I-T-Y-P-T-T-S-P-E-I-A-L-P-E-L-D-G-K-T-A-K-M-Y-R-G-G-K-I-C-L-T-D-H-F-K-P-L-W-A-R-N-V-P-K-F-G-I-A-H-A-M-A-L-G-L-A-P-W-L-A-V-E-V-P-D-L-I-E-K-G-V-I-S-Y-Q-E-K-G-S-S"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-A-D-R-L-T-Q-L-Q-D-T-V-N-Q-Q-A-E-H-F-C-N-S-I-G-I-L-Q-Q-C-S-V-P-S-K-F-A-G-F-E-R-T-G-S-Q-T-P-Q-Q-Q-V-H-Q-Q-Q-Q-L-P-Q-Q-Q-Q-Q-Q-Q-Q-P-Q-Q-Q-E-D-F-P-Q-L-F-S-T-L-I-S-R-C-A-K-D-I-D-T-L-I-E-S-L-P-S-E-E-S-S-I-E-L-Q-V-Q-S-L-Q-R-L-E-A-E-N-K-E-S-A-E-K-L-E-E-I-V-R-K-G-E-L-L-L-E-K-I-Q-A-A-L-S-D-I-A-Q-S-Q-L-D-M-Q-Y-S-S"} +{"text": "### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs Pol II is the central component of the basal RNA polymerase II transcription machinery It is composed of mobile elements that move relative to each other RPB11 is part of the core element with the central large cleft ### SEQUENCE -M-N-A-P-P-T-F-E-S-F-L-L-Y-E-G-E-K-K-I-I-K-E-L-D-M-K-V-P-N-A-A-I-F-T-V-N-K-E-D-H-T-L-G-N-M-I-R-N-Q-L-L-K-D-P-N-V-L-F-A-G-Y-K-L-P-H-P-L-E-H-K-F-V-L-R-I-Q-T-T-S-E-Y-S-P-H-E-A-F-M-N-A-I-T-D-L-L-S-E-L-S-L-F-E-E-R-F-R-E-A-M-K-E-K-K-E-G-G-D"} +{"text": "### FUNCTION Ubiquitin-like modifier protein which binds to a number of as yet unidentified target proteins ### SEQUENCE -M-A-A-S-K-V-T-F-K-I-T-L-T-S-D-P-K-L-P-F-K-V-L-S-V-P-E-A-T-P-F-T-A-V-L-K-F-A-A-E-E-F-K-V-P-P-A-T-S-A-I-I-T-D-D-G-I-G-I-N-P-Q-Q-T-A-G-T-V-F-L-K-H-G-S-E-L-R-L-I-P-R-D-R-V-G-C-R-C"} +{"text": "### FUNCTION Component of the transcription regulatory histone acetylation complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription ### SEQUENCE -M-S-E-N-D-G-I-H-I-E-Y-V-D-E-Q-E-L-K-R-E-F-R-R-F-M-S-D-P-E-T-R-E-K-A-A-N-Y-L-Y-E-S-L-V-D-E-T-I-L-G-I-A-Y-E-V-H-H-A-N-K-T-G-S-G-A-A-V-E-G-E-P-E-D-S-K-P-Y-T-I-V-D-Q-P-D-T-D-V-F-G-S-S-N-T-K-K-A-I-D-C-H-C-P-N-C-N-R-I-V-A-A-S-R-F-A-P-H-L-E-K-C-M-G-M-G-R-N-S-S-R-I-A-S-R-R-I-A-N-T-R-D-V-G-T-G-N-Y-F-G-G-D-E-D-D-E-D-D-A-D-W-S-G-E-K-R-K-K-K-I-S-Q-V-R-T-N-G-S-K-K-N-G-K-T-S"} +{"text": "### FUNCTION Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA Stimulates commitment or early complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region ### SEQUENCE -M-P-K-Y-Y-C-D-Y-C-D-T-Y-L-T-H-D-S-P-S-V-R-K-T-H-C-T-G-R-K-H-K-D-N-V-K-F-Y-Y-Q-K-W-M-E-E-Q-A-Q-H-L-I-D-A-T-T-A-A-Y-K-A-G-K-I-A-P-N-P-F-T-A-G-P-P-K-P-N-I-S-I-P-P-P-T-M-N-M-P-P-R-P-G-M-I-P-G-M-P-A-G-A-P-P-L-L-M-G-P-N-G-P-L-P-P-P-M-M-G-M-R-P-P-P-M-M-V-P-T-M-G-M-P-P-M-G-L-G-M-R-P-P-V-M-S-A-A-P-P-Q-L-N-P-K-S"} +{"text": "### FUNCTION Required for the function of the class 1 Sin3-histone deacetylase complex ### SEQUENCE -M-M-N-N-N-G-F-S-T-G-E-E-D-S-R-G-P-A-D-Q-I-C-C-L-L-D-D-G-E-R-C-R-K-Q-A-G-N-A-S-Y-S-K-R-I-Q-K-T-V-T-Q-R-R-L-K-L-S-I-D-S-H-A-R-H-I-Y-I-C-D-F-H-K-A-R-I-Q-C-A-R-T-K-R-R-R-R-D-S-E-D-D-S-N-E-T-D-T-D-L-P-E-V-D-L-Y-Q-L-Q-V-N-T-L-R-R-Y-K-R-F-Y-K-V-S-T-R-P-S-S-N-K-A-Q-L-S-E-T-I-M-K-H-F-K-T-I-P-I-K-E-K-E-I-L-T-Y-F-I-Y-M-V-K-S-N-S-N-K-L-D-Q-K-N-N-A-S-A-E-A-T"} +{"text": "### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-R-R-Q-Y-S-M-W-A-S-T-V-A-V-I-A-C-G-S-A-L-M-L-L-H-P-V-G-A-D-A-P-K-K-R-C-L-T-K-P-N-V-S-K-K-V-D-M-V-I-H-Q-C-Q-E-E-I-K-S-S-L-I-E-D-A-L-K-I-F-T-A-E-H-G-Q-W-H-D-R-R-K-R-D-E-G-G-L-D-F-S-H-P-T-I-V-S-H-E-D-K-W-I-A-G-C-L-M-Q-C-V-Y-R-K-N-N-A-I-D-K-N-G-W-P-T-L-D-G-L-V-S-L-Y-T-D-G-V-N-E-Q-G-Y-F-M-A-T-L-R-G-V-D-R-C-L-K-G-T-S-K-K-Y-Q-I-K-R-N-D-A-A-E-N-F-E-Q-C-E-V-A-F-D-V-F-D-C-I-S-D-M-I-T-D-Y-C-S-G-Q-M-E-D-D-H"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-T-S-P-L-E-N-L-E-N-H-L-E-M-F-I-E-N-V-R-Q-I-R-I-I-V-S-D-F-Q-P-Q-G-Q-N-V-L-N-Q-K-I-Q-S-L-V-T-G-L-Q-E-I-D-K-L-K-N-Q-I-D-V-N-V-P-L-E-V-F-D-Y-I-D-Q-G-R-N-P-Q-L-Y-T-K-D-C-I-D-K-A-L-T-K-N-E-E-V-K-G-K-I-D-S-Y-R-K-F-K-S-N-L-M-K-E-L-S-E-T-F-P-V-E-I-S-K-Y-K-A-I-R-G-D-E"} +{"text": "### FUNCTION Acts as a sulfur carrier required for 2-thiolation of mcm that is covalently conjugated via an isopeptide bond to lysine residues of target proteins The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates ### SEQUENCE -M-D-D-S-I-D-E-E-V-I-S-G-G-S-T-I-T-V-E-F-S-G-G-A-E-T-L-F-G-G-V-K-E-H-I-V-P-L-D-G-S-K-I-V-L-L-E-E-M-L-R-W-L-R-D-H-L-L-T-G-D-A-G-L-F-L-Q-E-N-T-V-R-P-G-I-L-V-M-I-N-D-T-D-W-D-L-M-G-E-T-E-Y-I-L-Q-P-G-D-H-I-L-F-I-S-T-L-H-G-G"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-Q-R-N-L-T-Q-S-K-E-A-L-L-K-S-Y-N-S-R-L-K-E-D-I-R-S-M-R-E-N-F-E-E-I-I-R-L-A-K-G-E-N-D-T-Q-L-S-K-I-T-Q-C-E-Q-D-T-Y-E-T-Q-V-R-A-A-N-I-V-R-A-G-E-S-L-M-K-L-V-S-D-I-K-Q-Y-L-I-L-N-D-F-H-S-V-N-E-A-I-C-S-N-S-T-L-Y-R-T-T-Q-I-D-R-D-N-K-L-M-A-V-R-D-D-M-A-A-D-L-Y-D-L-E-E-E-Y-Y-T-S-I-Y-K"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-K-I-W-K-D-V-F-T-G-D-E-M-F-S-D-T-Y-K-V-K-L-V-D-D-V-M-Y-E-V-Y-G-K-H-V-S-R-T-L-G-D-V-Q-L-D-G-A-N-P-S-A-E-E-A-E-E-G-T-E-S-A-T-E-S-G-V-D-I-V-L-N-H-R-L-V-E-T-G-F-S-D-K-K-Q-F-T-T-Y-L-K-D-Y-M-K-K-L-V-T-R-L-E-E-K-S-P-G-E-V-E-V-F-K-T-N-I-N-K-V-M-K-D-L-L-G-R-F-K-D-L-Q-F-F-T-G-E-S-M-D-C-E-G-L-I-A-M-L-E-Y-R-D-I-D-G-E-S-V-P-V-L-L-C-F-K-H-G-L-E-E-E-K-F"} +{"text": "### FUNCTION Essential regulatory subunit of the mitochondrial calcium uniporter channel, a protein that mediates calcium uptake into mitochondria ### SEQUENCE -M-V-L-T-R-V-I-R-A-V-G-R-S-T-L-L-E-T-G-V-A-G-S-G-G-G-Q-L-Q-L-V-R-L-P-L-R-R-K-Y-T-Y-R-S-G-A-L-K-P-M-P-E-I-T-P-F-G-L-F-G-I-I-A-T-V-I-P-G-L-L-I-G-A-T-I-S-K-N-M-A-N-F-L-E-E-N-D-L-F-V-P-S-D-D-D-D-D-D-D"} +{"text": "### FUNCTION GTP-binding protein involved in protein trafficking ### SEQUENCE -M-G-N-T-L-S-I-F-G-K-L-F-D-G-L-F-G-K-K-E-M-R-I-L-M-V-G-L-D-A-A-G-K-T-T-I-L-Y-K-L-K-L-G-E-V-V-T-T-I-P-T-I-G-F-N-V-E-T-V-E-Y-K-N-I-Q-F-T-V-W-D-V-G-G-Q-D-K-I-R-P-L-W-R-H-Y-F-Q-N-T-Q-G-I-I-F-V-V-D-S-N-D-R-D-R-V-V-E-A-R-E-E-L-Q-R-M-L-N-E-D-E-L-R-D-A-L-L-L-V-F-A-N-K-Q-D-L-P-N-A-M-N-A-A-E-I-T-D-K-L-G-L-S-S-L-R-Q-R-S-W-Y-I-Q-A-T-C-A-T-T-G-D-G-L-F-E-G-L-D-W-L-S-T-E-L-K-K-K-S-P"} +{"text": "### FUNCTION Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner In the complex, it is required to stimulate activity of mtHSP70 ### SEQUENCE -M-S-S-A-V-A-I-G-A-G-V-A-V-A-A-F-L-G-R-A-G-L-V-A-W-R-R-S-R-G-G-V-G-A-L-G-K-A-F-Y-K-G-G-F-E-P-R-M-N-K-K-E-A-S-L-I-L-S-L-N-E-R-T-I-T-K-D-K-I-R-K-A-H-R-T-L-M-L-L-N-H-P-D-R-G-G-S-P-Y-L-A-T-K-V-N-E-A-K-E-F-L-E-K-S-V"} +{"text": "### FUNCTION Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane ### SEQUENCE -M-S-D-S-T-S-S-P-V-A-A-A-P-S-T-A-M-T-R-P-V-S-E-A-L-L-N-E-K-W-D-R-C-L-S-N-L-L-I-K-S-T-L-G-L-G-F-G-V-V-F-S-V-L-I-F-K-R-R-A-W-P-A-F-V-G-V-G-F-G-A-G-R-A-Y-E-E-C-N-T-S-L-K-Q-A-A-R-E-I-R-A-Q-A"} +{"text": "### FUNCTION Involved in protein synthesis Involved in microtubule stabilization ### SEQUENCE -M-L-I-Y-S-D-I-I-T-G-D-E-I-I-S-D-S-Y-D-L-K-E-V-D-G-I-A-Y-E-V-D-C-A-M-I-E-E-G-A-V-Q-V-D-I-G-A-N-A-S-A-E-E-A-D-E-A-L-D-D-G-V-V-K-V-N-N-V-V-H-S-F-R-L-Q-S-T-Q-F-D-K-K-G-Y-L-V-Y-L-K-G-Y-M-K-S-V-K-N-A-L-K-E-Q-G-K-S-D-E-E-I-K-D-F-E-T-K-A-S-A-F-A-K-N-V-I-L-A-K-F-K-D-W-E-F-Y-T-G-E-S-M-N-P-D-G-M-V-V-L-L-N-Y-R-E-D-G-T-T-P-Y-V-V-V-W-K-H-G-L-K-E-T-K-V"} +{"text": "### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-G-K-D-K-K-A-S-G-S-G-S-G-S-K-G-G-K-D-A-G-N-K-D-A-G-K-D-A-G-K-A-S-K-G-A-Q-S-I-N-V-R-H-I-L-C-E-K-H-G-K-K-E-E-A-L-A-K-I-R-D-G-A-D-F-G-A-V-A-R-E-Y-S-E-D-K-A-R-T-G-G-S-L-G-W-K-Q-K-G-T-L-D-P-E-F-E-K-V-A-F-A-L-E-T-S-S-T-S-S-P-K-I-G-E-V-K-T-Q-F-G-Y-H-I-I-M-V-E-G-K-K"} +{"text": "### FUNCTION Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol ### SEQUENCE -M-R-L-S-A-A-V-I-A-L-L-S-T-S-A-A-A-F-S-V-Y-R-E-N-S-V-S-A-N-D-E-L-D-V-P-G-K-S-P-L-R-F-C-D-A-A-A-D-R-K-D-D-I-V-T-I-E-E-V-I-L-T-P-N-P-P-E-A-G-Q-T-L-T-I-E-A-S-G-I-V-K-E-A-I-E-E-G-A-Y-V-N-L-Q-V-K-Y-G-Y-I-R-L-I-N-T-S-A-D-L-C-K-E-M-K-N-V-E-L-E-C-P-I-K-K-G-R-L-S-I-T-K-N-V-E-L-P-K-E-I-P-P-G-K-Y-T-V-E-A-D-V-Y-N-S-D-D-K-H-I-T-C-L-T-A-T-V-F-F-G-R-K-T-L-G-F-L-D-D-L"} +{"text": "### FUNCTION DNA-binding protein that induces severe bending of DNA Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex ### SEQUENCE -M-P-K-A-A-A-K-S-K-T-T-G-K-V-E-K-R-R-A-K-K-D-P-N-A-P-K-R-G-L-S-A-Y-M-F-F-A-N-E-Q-R-E-N-V-R-E-E-N-P-G-V-S-F-G-Q-V-G-K-I-L-G-E-R-W-K-A-L-S-D-K-Q-R-A-P-Y-E-A-K-A-A-A-D-K-K-R-Y-E-D-E-K-Q-A-Y-N-A-E-A-D-E-E-E-S-S"} +{"text": "### FUNCTION Required for the assembly of the V0 complex of the vacuolar ATPase in the endoplasmic reticulum ### SEQUENCE -M-A-T-R-R-I-I-S-Q-E-K-T-L-L-E-K-D-D-R-I-G-S-S-P-A-A-S-E-K-S-N-I-T-P-A-V-P-A-S-V-I-I-K-L-L-A-F-T-F-A-M-I-V-I-P-I-S-S-Y-F-L-T-V-D-R-L-F-K-G-N-S-T-Y-A-G-A-T-A-A-I-M-A-N-V-V-L-I-G-Y-I-I-V-A-M-A-E-D-Q-S-D-Q-E-N-E-K-K-G-G-G-G-K-G-E-G-K-K-D-L"} +{"text": "### FUNCTION Required for the assembly of cytochrome c oxidase ### SEQUENCE -M-A-Q-A-G-S-E-N-K-E-P-W-N-E-E-T-R-A-K-F-E-G-K-S-R-S-E-Y-L-D-P-C-Q-E-A-A-Q-R-S-I-R-C-L-H-R-N-Q-G-D-R-T-M-C-S-D-Y-F-E-A-Y-R-E-C-K-K-Q-W-I-E-R-R-R-E-Q-K-R-K-A-G-A-L-F"} +{"text": "### FUNCTION Golgi membrane protein involved in vesicular trafficking ### SEQUENCE -M-A-L-K-D-E-F-A-T-R-N-F-S-I-Y-G-Q-W-L-G-I-L-S-M-I-L-C-F-A-L-G-I-A-N-I-F-T-F-R-P-I-I-I-V-F-S-V-I-T-L-C-F-S-F-V-I-L-F-V-E-V-P-L-L-L-R-I-C-P-T-S-P-T-F-D-N-L-I-R-K-I-S-T-N-Y-T-R-A-A-A-Y-G-V-M-A-V-V-V-F-L-S-C-I-D-R-T-T-S-L-L-V-P-G-I-F-L-S-F-T-G-I-C-Y-A-L-A-A-L-K-G-Q-A-F-V-G-S-K-T-L-G-G-A-G-V-A-Q-M-I-V"} +{"text": "### FUNCTION Mannose-binding lectin ### SEQUENCE -M-S-F-H-V-T-A-E-D-A-R-I-E-V-R-D-N-R-T-I-L-F-A-R-L-R-R-E-D-G-E-W-N-D-A-S-Y-E-L-D-Q-I-I-G-N-N-D-G-H-F-Q-W-G-G-Q-N-F-T-E-T-A-E-D-I-R-F-H-P-K-E-G-A-A-E-Q-P-I-L-R-A-R-L-R-D-C-N-G-E-F-H-D-R-D-V-N-L-T-E-I-V-E-N-V-N-G-E-F-Q-A-K-F"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-S-D-R-L-S-Q-L-Q-E-A-V-D-Q-L-M-E-Q-F-I-A-T-Y-F-Y-I-D-R-H-H-D-L-K-T-F-S-P-K-D-T-I-A-P-S-K-A-D-Q-P-P-E-V-D-T-L-P-P-D-V-F-Q-A-G-Q-L-E-L-A-R-D-L-I-T-R-E-Q-Q-I-E-Y-L-I-S-S-L-P-G-L-D-N-S-E-Q-D-Q-L-Q-S-I-K-E-L-E-E-E-L-N-V-A-E-K-Q-R-Q-E-A-V-K-E-K-D-E-V-L-V-K-L-D-Q-T-L-R-S-I-R-R-Y"} +{"text": "### FUNCTION Has a role in mitochondrial fission Has a role in outer membrane fission but not matrix separation ### SEQUENCE -M-T-Q-L-P-Y-A-V-D-A-E-T-P-L-N-P-A-E-L-N-V-L-R-A-Q-Y-E-K-E-G-E-M-V-G-V-Q-T-K-F-N-Y-A-W-G-L-V-K-S-N-V-R-A-D-Q-H-L-G-V-M-L-L-S-E-I-F-R-T-S-P-E-R-R-R-E-C-L-Y-Y-L-A-L-G-N-Y-K-L-G-N-Y-A-Q-A-R-K-Y-N-D-A-L-L-E-N-E-P-A-N-L-Q-A-A-N-L-R-A-L-I-D-D-K-V-T-K-E-G-L-M-G-V-A-I-I-S-G-V-A-V-A-A-G-V-I-G-G-V-L-L-R-N-L-G-R-K-R"} +{"text": "### FUNCTION Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis ### SEQUENCE -M-A-S-T-Q-P-K-N-D-A-K-S-T-E-P-K-P-E-Q-P-V-T-E-K-K-T-A-V-L-E-E-D-D-E-F-E-D-F-P-V-D-D-W-E-A-E-D-T-E-A-A-K-G-N-N-E-A-K-H-L-W-E-E-S-W-D-D-D-D-T-S-D-D-F-S-A-Q-L-K-E-E-L-K-K-V-E-A-A-K-K-R"} +{"text": "### FUNCTION Component of the adaptor complexes which link clathrin to receptors in coated vesicles Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration ### SEQUENCE -M-L-S-F-I-L-I-Q-N-R-Q-G-K-T-R-L-A-K-W-Y-V-P-Y-S-D-E-E-K-I-K-L-K-G-E-I-H-R-L-V-A-P-R-D-Q-K-Y-Q-S-N-F-V-E-F-R-N-H-K-V-V-Y-R-R-Y-A-G-L-F-F-C-A-C-V-D-T-N-D-N-E-L-A-Y-L-E-A-I-H-F-F-V-E-V-L-D-S-F-F-G-N-V-C-E-L-D-L-V-F-N-F-Y-K-V-Y-A-I-L-D-E-V-F-L-A-G-E-I-E-E-T-S-K-Q-V-V-L-T-R-L-E-H-L-D-K-L-E"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-A-P-A-A-S-G-A-K-K-Q-K-K-K-W-S-K-G-K-V-K-D-K-A-Q-H-A-V-I-L-D-K-S-T-S-D-K-L-Y-K-D-V-Q-S-Y-R-L-V-T-V-A-T-L-V-D-R-L-K-I-N-G-S-L-A-R-R-C-L-K-D-L-E-E-K-G-Q-I-K-Q-V-V-G-H-S-K-M-K-I-Y-T-R-A-I-G-A-D-E"} +{"text": "### FUNCTION May be involved in cellular response to stress Required to maintain mitochondrial DNA ### SEQUENCE -M-L-S-W-Y-K-A-Q-L-A-A-R-P-L-L-T-Q-A-V-T-T-S-I-L-F-G-V-G-D-V-A-A-Q-Q-L-V-D-R-R-G-L-S-N-H-D-L-T-R-T-G-R-M-V-L-Y-G-G-A-V-F-G-P-A-A-T-T-W-F-R-F-L-Q-K-R-V-V-V-P-G-S-T-N-K-T-I-L-A-R-V-A-A-D-Q-G-L-F-A-P-T-F-I-G-I-F-L-G-S-M-A-V-L-E-G-T-D-V-K-E-K-L-Q-K-N-Y-W-E-A-L-S-T-N-W-M-V-W-P-F-V-Q-M-V-N-F-K-V-V-P-L-D-H-R-V-L-F-V-N-V-I-S-I-G-W-N-C-Y-L-S-W-L-N-G-Q"} +{"text": "### FUNCTION Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit ### SEQUENCE -M-S-S-T-T-T-T-T-Q-T-T-S-Q-V-E-T-K-A-V-S-K-P-L-G-M-R-V-N-G-K-Q-W-H-A-P-K-K-A-F-R-P-G-S-G-L-T-S-Y-E-K-R-A-K-E-R-Q-L-L-A-A-V-K-A-K-E-K-E-L-K-D-E-K-E-A-E-R-K-R-R-I-E-A-L-K-E-K-R-A-K-K-E-E-K-E-R-Y-E-K-M-A-E-K-M-H-K-K-R-V-E-R-L-K-R-K-E-K-R-N-K-L-I-N-S"} +{"text": "### FUNCTION Essential for the assembly of ubiquinol-cytochrome c reductase It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b ### SEQUENCE -M-A-A-K-K-P-V-N-W-W-L-W-T-K-M-L-L-G-G-A-A-I-C-V-G-G-P-A-F-T-Y-W-L-T-P-T-D-E-E-L-F-Q-K-Y-N-P-E-L-Q-K-R-S-L-E-R-R-F-E-R-Q-Q-E-F-D-D-F-V-T-K-L-K-E-Y-S-K-S-D-K-P-I-W-T-V-Q-A-E-A-E-E-K-E-R-Q-Q-R-A-S-V-Q-K-S-L-A-L-A-D-E-V-K-A-R-K-E-A-M-R-R-E-A-G-L-P-L-E-K"} +{"text": "### FUNCTION Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A The NuA4 complex is also involved in DNA repair ### SEQUENCE -M-M-D-N-S-G-P-K-M-G-A-A-D-G-A-A-G-I-P-Y-Y-E-K-Q-R-Q-H-L-K-E-L-L-N-K-K-K-L-L-E-K-R-L-L-A-Q-E-E-S-I-Y-Q-K-E-T-E-Y-L-E-N-T-P-A-G-N-I-I-T-G-F-D-N-Y-T-K-G-T-A-N-V-A-A-Q-R-R-K-T-G-L-T-D-A-N-R-V-F-S-R-S-S-I-S-Y-N-P-A-A-Q-Q-D-S-Q-T-P-A-S-S-A-P-A-S-H-A-P-T-P-V-S-T-S-F-N-N-K-D-G-A-S-S-A-P-T-P-T-S-A-T-A-G-K-A-N-S-K-K-K-K-A-A-T-S-G-G-A-G-V-E-D-S-E-T-D-S-R-E-T-K-K-A-R-T-N-F-G-A-V-R-K"} +{"text": "### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase to ubiquinol Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants May act together with SDHAF1 ### SEQUENCE -M-Y-A-L-R-P-T-L-R-R-S-A-A-A-A-L-T-H-S-K-N-H-N-Y-G-M-T-P-G-P-L-A-L-L-P-P-I-Y-L-Y-R-R-L-L-R-A-H-R-K-Y-L-P-R-E-M-R-L-L-G-D-E-Y-V-K-A-E-F-R-A-H-R-S-V-D-N-P-A-H-L-I-G-F-L-T-E-W-Q-L-Y-A-Q-K-I-E-G-N-S-W-V-G-E-K-L-D-K-G-K-V-E-K-M-S-D-E-Q-I-G-Q-L-Y-E-L-M-Q-A-I-Q-K-R-G-T-E-G-D-L-E-D-G-D-G-G-E-S-G-Q-K-S-Q"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-A-S-D-P-M-S-V-N-S-S-A-R-E-P-P-A-P-P-G-S-G-A-D-E-P-K-Y-G-G-Y-T-R-F-E-L-E-L-E-F-V-Q-A-L-G-N-P-L-Y-L-N-H-L-A-S-R-K-L-L-S-N-P-A-F-I-A-Y-L-D-Y-L-Q-Y-W-S-R-P-P-Y-L-K-Y-I-T-Y-P-G-P-T-L-K-N-L-E-L-L-Q-Q-E-K-F-R-Q-D-I-I-S-P-D-L-V-E-R-L-R-L-E-G-M-K-A-G-I-D-W-H-R-E-S-F-P-S-T-A"} +{"text": "### FUNCTION Golgi membrane protein involved in vesicular trafficking ### SEQUENCE -M-M-E-A-T-P-T-P-G-S-L-S-W-R-L-S-S-H-P-I-T-L-L-T-F-L-A-F-R-S-S-S-L-L-V-Y-L-F-G-L-L-F-T-D-N-L-V-M-I-F-I-I-T-I-L-L-L-A-G-D-F-Y-Y-L-K-N-I-A-G-R-R-L-V-G-L-R-W-W-N-E-V-D-P-N-S-G-D-S-H-W-V-F-E-S-S-E-P-G-T-K-I-I-N-A-T-D-S-R-F-F-W-L-A-I-Y-A-Q-P-L-L-W-V-V-L-A-I-V-A-L-F-S-L-K-F-I-W-L-P-L-V-A-I-A-L-V-L-T-I-T-N-S-L-A-F-S-R-C-D-K-F-S-Q-A-S-N-I-A-G-T-A-F-S-S-G-N-I-A-G-N-I-A-S-N-M-V-G-R-F-F-S-R"} +{"text": "### FUNCTION Highly reducing polyketide synthase ### SEQUENCE -M-A-P-P-N-K-N-P-N-G-Y-Y-V-E-S-F-P-A-P-G-L-R-Q-I-V-R-H-I-T-G-L-N-K-Q-G-E-S-V-F-L-H-S-D-H-G-D-H-H-R-F-M-V-Q-N-Q-A-I-S-N-L-L-Y-S-T-Q-E-T-P-V-D-L-N-N-N-I-D-I-Q-K-A-K-E-K-E-P-P-F-H-Y-K-S-G-S-I-V-R-M-I-D-F-G-P-G-V-E-S-P-L-H-R-A-M-T-I-D-Y-G-I-I-V-E-G-V-F-E-L-I-L-D-S-G-E-K-R-I-M-R-Q-G-D-V-S-V-Q-R-A-T-A-H-K-W-V-N-V-T-G-N-G-T-L-P-G-R-V-M-W-V-L-L-D-C-K-E-V-V-D-A-K-G-E-K-V-E-G-Y-L-G-S-L-Q-E-H-Y-E-G-R"} +{"text": "### FUNCTION Cupin-domain-containing oxidoreductase ### SEQUENCE -M-S-T-S-G-P-I-T-E-F-P-A-P-G-L-R-D-P-F-R-Y-I-T-G-H-D-A-E-G-N-A-V-F-V-Q-T-D-N-G-D-H-R-A-V-M-L-G-G-A-A-A-Q-N-I-I-Y-S-A-G-S-N-P-I-E-L-T-G-N-V-D-L-E-F-A-K-N-R-P-S-L-H-I-P-N-G-V-C-V-R-M-I-D-F-A-P-G-C-K-S-N-M-H-R-A-L-C-M-G-I-G-T-V-C-E-G-E-V-E-L-T-L-G-S-G-E-K-R-I-L-R-P-G-D-V-S-I-N-R-G-A-M-H-Q-W-R-N-T-S-D-E-K-P-A-R-M-L-Y-T-L-L-D-I-K-P-L-I-V-N-G-K-Q-L-D-F-D-M-G-Y-L-M-K-E-Y-A-E-Y-D-E-G-E-G-D-K-K-A-E"} +{"text": "### FUNCTION Required for the assembly of the mitochondrial respiratory chain complex IV , also known as cytochrome c oxidase May participate in merging the COX1 and COX2 assembly lines ### SEQUENCE -M-T-F-Q-S-K-K-F-P-S-T-A-N-T-N-T-F-A-A-K-Y-R-A-M-M-K-K-H-P-F-L-L-F-G-L-P-F-M-S-V-I-V-A-G-S-F-I-L-T-P-A-A-A-I-R-Y-E-K-Y-D-R-K-V-R-Q-V-S-R-E-E-E-L-G-L-G-Q-R-K-R-R-V-D-I-R-E-E-Y-Y-R-L-A-A-K-D-L-D-N-W-E-Q-K-R-V-E-R-L-K-G-E-S-D-G-L-L"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-A-A-R-N-A-A-L-K-V-D-W-A-K-I-T-T-S-L-G-L-R-G-Q-T-A-A-S-L-Q-A-F-K-K-R-N-D-D-A-R-R-K-L-Q-Q-L-S-E-L-P-T-T-V-D-F-A-A-Y-R-S-T-L-K-N-Q-A-I-V-N-E-I-E-K-R-F-T-S-F-K-P-A-T-Y-D-V-N-R-Q-L-K-A-I-E-A-F-E-V-E-A-I-K-N-A-E-A-T-K-T-K-V-D-L-E-L-K-D-L-E-K-T-L-T-N-I-E-T-A-R-P-F-D-E-L-T-V-D-E-V-A-A-A-E-P-S-I-D-E-K-T-S-K-L-V-S-K-G-R-W-S-V-P-G-Y-K-E-R-F-G-D-L-S-V-L"} +{"text": "### FUNCTION Involved in resistance toward heavy metals ### SEQUENCE -M-E-E-V-V-L-I-T-V-P-S-E-E-V-A-R-T-I-A-K-A-L-V-E-E-R-L-A-A-C-V-N-I-V-P-G-L-T-S-I-Y-R-W-Q-G-E-V-V-E-D-Q-E-L-L-L-L-V-K-T-T-T-H-A-F-P-K-L-K-E-R-V-K-A-L-H-P-Y-T-V-P-E-I-V-A-L-P-I-A-E-G-N-R-E-Y-L-D-W-L-R-E-N-T-G"} +{"text": "### FUNCTION Transcriptional repressor Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CACTG-3' ### SEQUENCE -M-E-V-N-T-C-N-I-Q-V-L-L-Q-A-A-E-Y-L-E-R-R-E-R-E-A-E-H-G-Y-A-S-V-L-P-F-Y-S-N-G-V-S-D-K-R-K-K-Q-K-S-K-S-H-S-S-P-G-N-S-R-S-V-H-N-E-L-E-K-H-R-R-A-Q-L-R-H-C-L-E-Q-L-K-Q-Q-V-P-L-S-S-D-S-S-R-N-T-T-L-N-L-L-R-Q-A-Q-L-H-I-K-K-L-Q-E-Q-D-E-R-A-K-L-L-K-D-R-L-R-W-E-Q-R-E-L-R-T-R-L-E-K-L-Q-G-G-S-E-R-M-R-S-D-S-L-G-S-A-V-S-S-E-R-S-D-S-E-R-E-D-V-E-I-D-V-E-S-M-V-W-T-L-E-A-D-A-L-G-S-S-H-A-G-V-D-H-S-Y-S-T-S-D-H-A-W-L"} +{"text": "### FUNCTION Stores iron in a soluble, non-toxic, readily available form Important for iron homeostasis Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation ### SEQUENCE -M-S-A-Q-S-Q-I-R-Q-N-Y-H-E-E-S-E-A-G-V-N-R-I-A-N-L-E-L-Q-A-S-Y-L-Y-L-S-V-G-Y-Y-F-D-R-D-D-V-A-L-S-K-F-S-K-F-F-R-E-L-S-E-K-K-R-D-H-A-E-D-F-L-K-F-Q-N-K-R-G-G-R-V-V-L-Q-D-V-K-K-P-D-D-D-E-W-G-N-G-T-K-A-M-E-V-A-L-N-L-E-K-S-I-N-Q-A-V-L-D-L-H-K-I-A-T-D-H-T-D-P-H-M-Q-D-Y-L-E-H-E-F-L-E-E-E-V-K-L-I-K-K-L-G-D-H-L-T-N-L-R-R-V-K-A-A-E-E-G-M-G-E-Y-L-F-D-K-L-T-L-G-E-D"} +{"text": "### FUNCTION May play a role into cellular response to oxidative stress May decrease cell proliferation ### SEQUENCE -M-S-K-A-T-K-R-K-H-V-V-K-E-V-L-E-D-Y-V-T-P-T-E-D-Q-Q-I-M-R-V-L-G-S-N-G-N-N-L-H-E-A-V-T-G-S-G-E-R-F-L-L-S-M-P-T-K-F-R-K-N-I-W-I-K-R-G-D-F-V-I-V-D-P-I-K-E-G-G-K-V-K-G-E-I-S-F-I-L-Y-R-D-H-I-Q-H-L-R-K-L-G-V-W-P-E-G-F-Q-E-D-R-T-S-G-E-R-N-E-G-T-Q-K-E-R-S-E-E-K-E-E-E-E-G-D-S-E-S-E-D-D-D-S-D-L-F-V-N-T-N-R-A-T-V-L-Y-S-E-S-E-E-E-T-D-E-D-E-E-E-D-K-G-R-A"} +{"text": "### FUNCTION May be involved in the calcium-dependent regulation of rhodopsin phosphorylation Binds three calcium ions ### SEQUENCE -M-G-K-Q-N-S-K-L-R-P-E-V-M-Q-D-L-L-E-S-T-D-F-T-E-H-E-I-Q-E-W-Y-K-G-F-L-R-D-C-P-S-G-N-L-T-M-E-E-F-K-K-I-Y-G-N-F-F-P-Y-G-D-A-S-K-F-A-E-H-V-F-R-T-F-D-A-N-G-D-G-T-I-D-F-R-E-F-I-I-A-L-S-V-T-S-R-G-K-L-E-Q-K-L-K-W-A-F-S-M-Y-D-L-D-G-N-G-Y-I-S-K-A-E-M-L-E-I-V-Q-A-I-Y-K-M-V-S-S-V-M-K-M-P-E-D-E-S-T-P-E-K-R-T-E-K-I-F-R-Q-M-D-T-N-R-D-G-K-L-S-L-E-E-F-I-R-G-A-K-S-D-P-S-I-V-R-L-L-Q-C-D-P-S-S-A-G-R-F"} +{"text": "### FUNCTION Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction Covalent attachment to its substrates requires prior activation by the E1 complex sae1-sae2 and linkage to the E2 enzyme ube2i ### SEQUENCE -M-S-E-E-K-P-K-E-G-V-K-T-E-N-D-H-I-N-L-K-V-A-G-Q-D-G-S-V-V-Q-F-K-I-K-R-H-T-P-L-S-K-L-M-K-A-Y-C-D-R-Q-G-L-S-M-R-Q-I-R-F-R-F-D-G-Q-P-I-N-E-T-D-T-P-A-Q-L-E-M-E-D-E-D-T-I-D-V-F-Q-Q-Q-T-G-G-V-C"} +{"text": "### FUNCTION May be involved in ciliary biogenesis or function ### SEQUENCE -M-A-D-V-V-L-G-V-G-T-G-V-F-I-I-T-L-I-W-I-L-T-L-A-L-T-I-I-L-S-R-A-T-G-P-T-K-L-G-I-I-P-V-V-L-L-A-L-I-I-T-L-V-L-V-F-F-P-R-A-A-E-V-P-A-P-Q-R-A-A-Q-I-V-D-M-F-F-I-G-R-Y-V-L-L-S-L-V-S-L-V-F-L-A-A-L-F-M-L-L-P-L-H-F-L-E-P-I-Y-A-K-P-L-R-T-H"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-K-R-T-K-K-V-G-I-V-G-K-Y-G-T-R-F-G-A-S-L-R-K-M-V-K-K-I-E-I-S-Q-H-A-K-Y-T-C-S-F-C-G-K-T-K-M-K-R-K-A-V-G-I-W-H-C-G-S-C-M-K-I-V-A-G-G-A-W-T-Y-N-T-T-S-A-V-T-V-K-S-A-I-R-R-L-K-E-L-K-D-Q"} +{"text": "### FUNCTION Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum ### SEQUENCE -M-D-Q-I-M-Q-F-V-E-P-S-R-Q-F-V-K-D-S-I-R-L-V-K-R-C-T-K-P-D-R-K-E-F-Q-K-I-A-M-A-T-A-I-G-F-A-I-M-G-F-I-G-F-F-V-K-L-I-H-I-P-I-N-N-I-I-V-G-G"} +{"text": "### FUNCTION Anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factor IX in the presence of calcium with a 1 to 1 stoichiometry ### SEQUENCE -Y-E-G-H-C-Y-Q-T-F-K-L-F-K-T-W-A-D-A-E-S-F-C-T-E-Q-A-K-G-G-H-L-V-S-I-E-S-D-G-E-A-D-F-V-A-Q-L-V-A-E-N-I-Q-K-T-E-I-Y-V-W-V-G-L-R-V-Q-G-K-E-Q-Q-C-S-S-E-W-S-D-G-S-S-V-S-Y-Q-N-W-I-E-A-E-S-K-T-C-L-G-L-Q-K-E-T-E-F-R-K-W-F-N-I-Y-C-G-E-R-N-P-F-V-C-E-A"} +{"text": "### FUNCTION Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly ### SEQUENCE -M-A-K-V-Q-I-L-N-M-V-V-L-D-N-P-C-P-F-H-N-P-F-Q-F-E-I-T-F-E-C-I-E-D-L-P-D-D-L-E-W-K-I-I-Y-V-G-S-A-E-S-E-E-Y-D-Q-T-L-D-S-V-L-V-G-P-V-P-A-G-R-H-M-F-V-F-Q-A-D-A-P-N-C-S-L-I-P-E-S-D-A-V-G-V-T-V-V-L-I-T-C-T-Y-R-G-Q-E-F-I-R-V-G-Y-Y-V-N-N-E-Y-S-D-P-E-L-R-E-N-P-P-L-K-A-H-F-G-Q-L-Q-R-N-I-L-A-S-N-P-R-V-T-R-F-H-I-N-W-E-C-T-S-E-A-K-M-E-D-I-E-N-V-D-P-A-S-N-T-M-L-P-P-N-C-A-P-S-K-G-L-A-A-A-L-N-T-L-P-E-N-S-M-D-C-M"} +{"text": "### FUNCTION Regulates NF-kappa-B transcription factor activity Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation Promotes cardiac muscle hypertrophy Plays a role in the regulation of the growth of actin filaments Inhibits the activity of the F-actin-capping protein complex ### SEQUENCE -M-G-D-K-E-F-M-W-A-L-K-N-G-D-L-D-A-V-K-E-F-V-A-G-G-V-D-V-N-R-T-L-E-G-G-R-K-P-L-H-Y-A-A-D-C-G-Q-D-E-I-V-E-F-L-L-A-K-G-A-N-I-N-A-A-D-K-H-G-I-T-P-L-L-S-A-C-Y-E-G-H-R-K-C-V-E-L-F-V-S-K-G-A-D-K-N-V-K-G-P-D-G-L-N-A-F-E-S-T-D-N-Q-A-I-K-D-L-L-H"} +{"text": "### FUNCTION Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids Adapter protein that may regulate the MAP kinase cascade ### SEQUENCE -M-A-E-E-L-K-R-F-L-Y-K-K-L-P-S-I-E-G-L-H-A-I-V-V-S-D-R-D-G-V-P-V-I-K-V-A-N-E-N-A-P-E-L-A-L-R-P-S-F-L-S-T-F-A-L-A-T-D-Q-G-S-K-L-G-L-S-K-N-K-S-I-I-C-Y-Y-D-T-C-Q-V-V-Q-F-N-R-L-P-L-V-V-S-F-I-A-S-S-D-A-N-T-G-L-L-L-S-L-N-E-E-L-G-D-L-F-E-E-L-Q-H-A-V-E-I"} +{"text": "### FUNCTION Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor ### SEQUENCE -M-P-A-Y-H-S-I-L-M-E-S-D-T-K-L-I-G-N-M-A-M-L-P-I-R-S-Q-F-K-G-P-A-P-R-E-T-K-D-T-D-I-I-D-E-A-I-Y-Y-F-K-A-N-V-F-F-K-N-Y-E-I-K-N-E-A-D-R-T-L-I-Y-I-T-L-Y-I-S-E-C-L-K-K-L-Q-K-C-N-S-K-G-Q-G-E-K-E-M-Y-T-L-G-I-T-N-F-P-I-P-G-E-P-G-F-P-L-N-A-M-Y-V-K-P-S-N-K-Q-E-D-E-V-M-R-A-Y-L-Q-Q-L-R-Q-E-T-G-L-R-L-C-D-K-V-F-D-P-Q-T-D-K-P-S-K-W-W-I-C-F-V-K-K-Q-F-M-N-K-S-L-S-G-P-G-Q"} +{"text": "### FUNCTION Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids Adapter protein that may regulate the MAP kinase cascade ### SEQUENCE -M-A-E-E-L-R-R-F-L-Y-K-K-L-T-S-V-E-G-L-H-A-I-V-V-S-D-R-D-G-V-P-V-I-K-V-A-N-E-N-A-P-E-Q-A-L-R-P-A-F-L-S-T-F-A-L-A-T-D-Q-G-S-K-L-G-L-S-K-N-K-S-I-I-C-Y-Y-S-T-Y-Q-V-V-Q-F-N-Q-L-P-L-V-V-S-F-I-A-S-S-N-A-N-T-G-L-I-L-S-L-E-K-E-L-G-S-L-F-K-E-L-R-Q-A-V-I-S"} +{"text": "### FUNCTION Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum ### SEQUENCE -M-D-Q-V-M-Q-F-V-E-P-S-R-Q-F-V-K-D-S-I-R-L-V-K-R-C-T-K-P-D-R-K-E-F-Q-K-V-A-M-A-T-A-I-G-F-A-I-M-G-F-I-G-F-F-V-K-L-I-H-I-P-I-N-N-I-I-V-G-G"} +{"text": "### FUNCTION Functions as a component of numerous distinct DCX E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex ### SEQUENCE -M-D-K-A-D-F-L-K-G-L-P-V-Y-N-K-T-N-F-S-R-F-H-A-D-S-V-C-K-A-S-N-R-R-P-S-V-Y-L-P-T-R-E-Y-P-S-E-Q-I-I-V-T-E-K-T-N-I-L-L-R-Y-L-H-Q-Q-W-D-K-K-N-A-A-K-K-R-E-Q-E-Q-A-E-G-E-G-G-S-P-A-P-P-R-K-I-A-R-T-D-S-Q-E-M-N-E-D-S"} +{"text": "### FUNCTION Regulates NF-kappa-B transcription factor activity Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation Promotes cardiac muscle hypertrophy Plays a role in the regulation of the growth of actin filaments Inhibits the activity of the F-actin-capping protein complex ### SEQUENCE -M-G-D-K-E-L-M-W-A-L-K-N-G-D-L-D-E-V-K-N-I-L-V-K-A-E-D-V-N-R-T-L-E-G-G-R-K-P-L-H-Y-A-A-D-C-G-Q-A-E-M-L-E-F-L-L-S-K-G-A-D-V-N-A-P-D-K-H-G-I-T-P-L-L-S-A-T-Y-E-G-H-V-T-C-V-K-I-L-L-E-K-G-A-D-K-N-R-K-G-P-D-G-L-S-A-F-E-A-A-E-S-E-A-I-K-A-L-L-E"} +{"text": "### FUNCTION Binds to muscle nicotinic acetylcholine receptor and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-R-C-F-N-Q-Q-S-S-E-P-Q-T-N-K-S-C-P-P-G-E-N-S-C-Y-R-K-Q-W-R-D-H-R-G-T-I-I-E-R-G-C-G-C-P-T-V-K-P-G-V-K-L-R-C-C-E-S-E-D-C-N-N"} +{"text": "### FUNCTION Binds with high affinity to muscular and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission ### SEQUENCE -K-T-L-L-L-T-L-V-V-V-T-I-I-C-L-D-F-G-Y-T-R-I-C-F-K-T-P-Y-V-K-S-E-T-C-P-P-G-Q-E-L-C-Y-T-K-T-W-C-D-R-F-C-S-I-R-G-K-V-I-E-L-G-C-T-A-T-C-P-R-A-E-P-K-E-D-T-T-C-C-S-K-D-N-C-N-P-H-P"} +{"text": "### FUNCTION May play a role in bone development ### SEQUENCE -M-S-E-T-N-Q-Q-R-D-D-L-P-A-Y-L-N-D-E-P-P-A-D-A-N-K-D-H-P-Q-P-Q-P-G-M-F-S-R-V-A-G-G-L-F-S-V-T-K-G-A-V-G-A-T-V-G-G-V-A-W-V-G-G-K-S-F-D-L-T-K-T-A-V-T-S-V-A-S-V-P-A-M-G-V-G-L-V-K-G-G-V-S-A-V-A-G-G-V-T-A-V-G-S-A-V-V-S-K-V-P-I-G-G-G-K-K-K-D-K-S-D"} +{"text": "### FUNCTION Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis Negative regulator of Toll-like receptor and T-cell receptor function Prevents hyperresponsiveness of the immune system and maintains immune homeostasis Inhibits jun/ap1 and NF-kappa-B activation Promotes Fas-induced apoptosis ### SEQUENCE -M-E-T-F-S-S-K-D-M-A-L-K-A-Q-K-K-I-L-S-K-M-A-T-K-S-M-V-Q-M-I-I-D-D-T-S-S-E-I-L-D-E-L-Y-R-V-S-K-E-Y-T-G-N-R-S-E-A-Q-K-V-V-K-D-L-I-K-V-V-V-K-I-G-V-L-F-R-H-N-R-F-N-E-E-E-L-K-L-A-Q-N-F-Q-K-K-L-R-Q-G-A-M-T-A-I-S-F-H-E-V-D-F-T-F-D-K-T-V-M-S-D-I-L-T-E-S-R-D-M-L-L-K-L-V-N-T-H-L-T-T-K-S-H-G-R-I-N-H-V-F-N-H-Y-A-D-P-E-L-L-T-Q-L-Y-N-S-S-G-P-L-K-P-H-L-N-K-I-C-N-G-L-N-K-L-L-E-N-G-T-L"} +{"text": "### FUNCTION Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding Calcium-binding is required for the activation of calmodulin Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II , and phosphatases ### SEQUENCE -M-A-D-Q-L-T-E-E-Q-I-A-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-T-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-Q-D-M-I-N-E-V-D-A-D-G-N-G-T-I-D-F-P-E-F-L-T-M-M-A-R-K-M-K-D-T-D-S-E-E-E-I-R-E-A-F-R-V-F-D-K-D-G-N-G-Y-I-S-A-A-E-L-R-H-V-M-T-N-L-G-E-K-L-T-D-E-E-V-D-E-M-I-R-E-A-D-I-D-G-D-G-Q-V-N-Y-E-E-F-V-Q-I-M-T-A-K"} +{"text": "### FUNCTION May function in the formation of membrane-bound replication complexes or in the assembly of the virus ### SEQUENCE -M-L-V-F-L-H-A-V-F-V-T-V-L-I-L-L-L-I-G-R-L-Q-L-L-E-R-L-L-L-N-H-S-L-N-L-K-T-V-N-N-V-L-G-V-T-D-T-G-L-K-V-N-C-L-Q-L-L-K-P-D-C-L-D-F-N-I-L-Y-R-S-L-A-E-T-R-L-L-K-V-V-L-R-V-I-F-L-V-L-L-G-F-C-C-H-R-L-L-V-T-L-F"} +{"text": "### FUNCTION Plays a central role in virus morphogenesis and assembly Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport Also plays a role in the induction of apoptosis ### SEQUENCE -M-T-F-P-R-A-L-T-V-I-D-D-N-G-M-V-I-S-I-I-F-W-L-L-L-I-I-I-L-I-L-F-S-I-A-L-L-N-I-I-K-L-C-M-V-C-C-N-L-G-R-T-V-V-V-I-P-V-R-H-A-Y-D-A-Y-K-N-F-M-R-I-N-A-Y-N-H-N-E-A-L-L-V"} +{"text": "### FUNCTION Cell-to-cell movement function ### SEQUENCE -M-K-V-L-L-V-T-G-V-L-G-L-L-L-L-I-K-W-K-S-Q-S-T-S-T-S-N-Q-T-C-Q-C-P-T-S-P-W-V-I-Y-A-F-Y-N-S-L-S-L-V-L-L-L-C-H-L-I-P-E-I-K-P-I-H-T-S-Y-N-T-H-D-S-S-K-Q-Q-H-I-S-I-N-T-G-N-G-K"} +{"text": "### FUNCTION May be involved in cell cycle regulation ### SEQUENCE -M-G-A-S-C-T-A-T-Q-S-Q-F-L-L-Y-T-L-T-S-S-E-E-T-V-G-S-V-G-D-S-C-R-G-P-E-E-E-A-E-K-P-V-K-T-K-T-V-S-S-S-N-G-G-E-S-S-S-R-S-A-E-K-R-S-A-E-D-E-A-A-D-L-P-T-K-P-T-K-M-S-K-F-G-F-A-I-G-S-Q-T-A-R-K-A-S-A-I-S-I-R-L-G-A-S-K-P-K-E-T-V-P-T-L-A-P-K-T-L-S-V-A-A-A-F-N-E-D-E-D-S-E-P-E-E-M-P-P-E-A-K-M-R-M-K-N-I-G-R-D-T-P-T-S-A-G-P-N-S-F-N-K-G-K-H-G-F-S-D-N-Q-K-L-W-E-R-N-I-K-S-H-L-G-N-V-H-D-Q-D-N"} +{"text": "### FUNCTION Does not bind lactose, and may not bind carbohydrates ### SEQUENCE -M-A-G-L-G-A-N-S-D-V-M-V-K-L-D-D-G-H-L-N-N-S-L-R-S-P-V-Q-A-G-V-Y-F-R-G-H-I-K-G-G-M-R-P-G-K-K-V-L-V-M-G-I-V-D-H-N-P-K-S-F-A-I-S-L-T-C-G-D-S-E-D-P-P-A-D-V-A-I-E-L-K-V-V-F-T-N-Q-Q-V-F-R-N-S-C-I-S-G-E-S-D-E-E-N-L-A-F-P-Y-F-P-F-V-P-D-Q-P-F-R-M-E-I-F-C-Q-Q-P-C-F-R-V-L-V-D-G-H-H-L-F-D-F-Y-H-R-I-Q-T-L-S-A-I-D-S-I-K-I-S-G-D-L-Q-I-T-K-L-G"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-F-E-F-P-A-S-F-R-F-A-D-S-H-E-Y-A-N-A-D-G-E-L-V-R-V-G-I-S-A-F-A-V-D-Q-L-G-D-I-V-F-V-D-L-P-D-V-G-D-S-L-D-K-G-A-T-F-G-S-V-E-S-V-K-A-V-E-D-M-Y-A-P-V-A-G-E-V-V-Q-R-N-E-A-V-L-A-S-P-E-E-L-Q-N-D-P-H-G-E-G-W-L-L-V-L-R-P-S-D-P-S-Q-L-E-A-L-M-D-A-G-T-Y-G-T-K-V-N-A-G"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-Q-G-R-R-V-E-R-V-A-A-L-I-R-K-E-T-S-E-L-L-I-N-G-I-R-D-E-R-V-H-Q-G-M-V-S-I-T-N-V-E-V-S-G-D-L-Q-H-C-K-I-F-V-S-I-F-G-D-E-A-S-Q-L-Q-V-M-E-G-L-Q-A-A-S-G-Y-L-K-G-E-L-G-R-R-L-Q-M-R-R-A-P-D-V-V-F-Q-L-D-R-G-I-E-R-G-T-S-V-L-G-L-L-N-K-L-E-D-E-R-K-E-R-G-E-I-P-A-G-S-D-E-L-P-A-E"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-Q-T-Y-I-R-S-I-P-D-F-P-K-P-G-I-L-F-R-D-I-N-P-L-L-R-N-P-A-A-M-V-E-V-M-R-R-L-G-A-I-C-D-A-V-Q-P-D-L-I-V-G-I-E-S-R-G-F-I-V-G-T-P-L-A-L-Q-R-S-L-G-F-V-P-V-R-K-P-G-K-L-P-G-A-V-I-G-V-D-Y-A-L-E-Y-G-T-D-R-L-E-I-Q-S-D-A-L-T-G-N-P-R-V-L-V-V-D-D-L-L-A-T-G-G-T-A-A-A-T-G-S-L-V-R-A-A-G-G-E-L-V-G-F-A-F-V-I-E-L-E-P-L-G-G-R-S-A-L-P-D-E-V-L-A-E-S-L-I-R-Y-P"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-A-V-S-L-S-V-S-T-V-K-P-L-G-D-R-V-F-I-K-V-S-E-S-E-E-K-T-A-G-G-I-L-L-P-D-T-A-K-E-K-P-Q-V-G-E-V-V-Q-V-G-P-G-K-R-N-D-D-G-S-R-Q-A-P-E-V-G-V-G-D-K-V-L-Y-S-K-Y-A-G-T-D-I-K-L-G-G-D-E-F-V-L-L-T-E-K-D-I-L-A-I-V-N"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-Y-K-F-P-N-Y-L-R-Y-A-D-T-H-E-Y-V-K-E-E-N-G-L-F-K-I-G-V-S-E-F-A-I-D-Q-L-G-D-I-V-F-V-E-L-V-E-K-G-T-N-L-Q-K-G-E-T-F-G-T-I-E-S-V-K-A-V-E-E-V-Y-L-P-F-S-G-E-V-I-S-V-N-E-G-V-I-D-N-P-E-I-L-Q-N-D-P-I-G-D-G-W-L-L-I-I-K-S-E-S-N-V-L-L-D-E-L-M-N-S-D-E-Y-K-S-K-V-V-P-N"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-P-P-R-P-R-F-D-R-R-A-P-V-R-E-L-P-N-I-N-E-R-I-K-Y-P-Q-L-R-V-V-D-S-D-G-K-Q-L-G-V-I-D-R-I-K-A-L-E-I-A-H-Q-R-G-L-D-L-V-L-V-S-E-K-A-N-P-P-V-C-R-I-M-D-Y-G-K-Y-K-F-E-Q-E-K-K-A-K-E-T-K-K-K-S-H-Q-T-E-V-K-E-V-K-M-R-Y-K-I-D-K-H-D-Y-D-V-R-I-G-Q-A-V-R-F-L-K-S-G-D-K-V-K-C-T-V-F-F-R-G-R-E-I-Q-H-S-N-L-A-E-T-L-L-L-K-M-A-N-D-L-E-E-Q-S-E-V-Q-Q-R-P-K-R-E-G-R-N-M-I-M-F-L-S-P-R-K-T-P-L-I-K-K-E-E-G"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-I-A-D-S-L-L-K-K-V-E-K-Q-N-T-D-N-D-K-S-V-I-K-T-W-S-R-S-S-T-I-L-P-V-M-I-G-H-T-I-A-V-H-N-G-K-A-H-I-P-V-F-I-T-E-Q-M-I-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-L-R-D-K-K-G-A-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-L-K-E-R-I-G-T-V-V-S-D-K-M-D-K-T-V-V-V-A-V-I-N-R-Y-P-H-P-T-Y-K-K-I-V-S-K-T-T-R-Y-K-A-H-D-P-E-N-S-C-V-L-G-D-R-V-K-I-K-E-T-R-P-L-S-A-H-K-R-W-A-I-E-E-I-L-N-K-T-I-M-S-K-E-D-K-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-Y-L-T-V-A-D-N-S-G-A-K-R-L-Q-C-I-R-V-L-G-S-N-R-R-Y-A-H-V-G-D-V-V-V-A-S-V-K-D-A-L-P-N-M-G-V-K-K-S-D-V-V-K-A-V-I-V-R-T-R-H-T-L-R-R-N-T-G-N-S-I-R-F-D-D-N-A-A-V-L-I-N-E-D-K-N-P-K-G-T-R-V-F-G-P-V-A-R-E-L-R-D-K-N-F-T-K-I-V-S-L-A-P-E-V-I"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-N-K-S-A-K-K-R-I-Q-V-A-E-R-N-R-L-V-N-K-S-Y-K-S-T-V-R-T-L-T-K-K-T-L-A-N-C-E-K-Y-K-Q-E-P-N-S-D-N-K-D-L-V-L-V-S-V-N-Q-A-F-S-L-I-D-K-A-V-K-K-N-V-L-H-K-N-N-G-A-N-K-K-S-K-I-N-K-V-V-K-D-F-L-T-S-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-I-S-L-K-V-L-A-P-N-Q-N-V-Y-E-G-D-A-E-E-V-I-L-P-S-T-T-G-Q-I-G-V-L-P-G-H-I-S-L-V-T-A-I-D-I-G-V-L-R-L-R-M-N-S-K-W-K-S-I-A-L-M-G-G-F-A-E-I-E-S-D-E-V-I-V-L-V-N-S-A-E-I-G-S-E-I-N-I-Q-N-A-E-D-A-L-K-K-A-K-S-A-I-S-K-F-P-E-N-E-K-S-S-E-K-I-K-A-L-N-E-V-S-K-A-E-A-R-I-Q-A-S-K-N"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-A-V-S-L-T-V-S-T-V-K-P-L-G-D-R-I-F-I-K-V-S-E-S-E-E-K-T-A-G-G-I-L-L-P-D-S-A-K-E-K-P-Q-V-G-E-V-A-Q-V-G-P-G-K-L-N-D-D-G-S-R-Q-T-P-E-V-S-I-G-D-K-V-L-Y-S-K-Y-A-G-T-D-I-K-L-G-G-D-E-Y-V-L-L-S-E-K-D-I-L-A-V-V-G"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-R-E-V-K-R-K-K-L-V-K-K-Y-A-T-K-R-K-S-L-L-D-E-F-N-A-A-K-D-P-M-E-R-L-E-I-H-R-K-I-Q-G-L-P-R-N-S-A-P-T-R-V-R-N-R-C-W-A-T-G-K-P-R-G-V-Y-R-D-F-G-L-C-R-N-Q-L-R-L-R-A-H-N-G-E-L-P-G-V-V-K-S-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-T-L-D-T-A-E-K-Q-K-L-I-E-S-H-Q-V-H-A-T-D-T-G-S-V-E-V-Q-V-A-M-L-S-E-R-I-S-K-L-S-D-H-L-Q-G-N-I-H-D-Y-A-S-R-Q-G-L-L-K-M-I-G-K-R-K-R-L-L-S-Y-I-K-G-K-N-P-Q-N-Y-Q-D-L-I-K-K-I-G-I-R-G"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-P-N-S-I-F-K-K-Q-L-S-P-I-K-P-G-D-P-I-D-Y-K-D-V-E-L-L-K-K-F-I-T-E-R-G-K-I-L-P-R-R-M-T-G-L-T-S-K-Q-Q-R-D-L-T-L-A-V-K-R-A-R-I-V-A-L-L-P-F-V-N-P-E-G"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-S-T-L-K-K-P-D-L-S-D-P-K-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-V-V-I-L-G-T-I-A-C-V-V-G-L-A-V-L-D-P-A-M-L-G-D-K-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-L-Y-P-V-F-Q-I-L-R-V-V-P-N-K-L-L-G-I-A-L-Q-T-L-I-P-L-G-L-M-I-L-P-F-I-E-N-V-N-K-F-S-N-P-F-R-R-P-V-A-M-S-V-F-L-F-G-T-F-L-T-I-Y-L-G-I-G-A-C-L-P-I-D-K-S-L-T-L-G-L-F"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-T-T-N-F-G-F-V-A-S-L-L-F-V-G-I-P-T-I-F-L-I-G-L-F-I-S-T-Q-D-G-E-K-S-S-F-Y-S-D-S-S-K-G-K-L-G-P-K-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-F-Q-F-P-D-H-F-R-F-A-D-T-H-E-Y-A-S-L-D-G-E-L-V-R-I-G-I-S-A-F-A-V-D-Q-L-G-D-I-V-F-V-D-L-P-E-V-G-D-R-L-N-R-G-T-T-F-G-S-V-E-S-V-K-A-V-E-D-L-H-A-P-I-S-G-E-L-V-R-I-N-E-S-V-L-S-S-P-D-E-L-Q-N-D-P-H-G-E-G-W-L-L-V-V-R-P-A-D-P-A-Q-L-Q-D-L-M-D-A-A-T-Y-A-N-K-V-A-I-E-S-S-N"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-K-I-T-A-K-D-V-R-K-V-A-Q-L-A-R-L-D-L-P-D-D-Q-I-A-T-Y-T-E-Q-L-E-R-I-L-A-Y-V-A-Q-L-E-E-I-D-T-T-N-V-K-P-T-T-R-A-V-E-V-V-N-V-T-R-T-D-E-V-S-E-T-P-V-R-E-E-L-L-N-L-A-P-Q-R-E-G-D-F-F-R-V-P-K-I-L-A-E"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-F-L-T-V-A-D-N-S-G-A-K-R-I-Q-C-I-R-V-L-G-S-N-R-R-Y-A-H-V-G-D-V-I-V-A-A-V-K-D-A-M-P-N-M-S-V-K-K-S-E-V-V-K-A-V-V-V-R-T-K-A-T-L-R-R-D-T-G-N-S-I-R-F-D-D-N-A-A-V-L-I-N-E-D-K-N-P-R-G-T-R-V-F-G-P-V-A-R-E-L-R-E-R-N-F-T-K-I-V-S-L-A-P-E-V-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-L-K-E-R-L-G-T-V-V-S-D-K-M-D-K-T-V-V-V-A-V-E-N-R-F-P-H-P-I-Y-Q-K-T-V-S-R-T-T-R-Y-K-A-H-D-A-G-N-T-C-R-V-G-D-R-V-R-I-T-E-T-R-P-L-S-R-S-K-R-W-T-V-A-E-V-L-S-H-S-P-K-A-Q-E-V-S-T"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-I-A-D-S-L-L-R-K-L-E-K-Q-N-A-D-D-D-K-S-V-I-K-T-W-S-R-A-S-T-I-L-P-M-M-I-G-H-T-I-A-V-H-N-G-R-S-H-V-P-V-F-I-T-E-Q-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-K-G-H-I-K-D-K-K-G-G-R"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-P-V-N-N-F-G-F-L-A-T-L-L-F-V-A-V-P-M-L-F-L-I-G-L-Y-I-Q-T-N-S-N-K-S"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-H-I-L-K-K-P-D-F-S-D-P-K-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-V-V-I-L-G-T-F-A-C-L-V-G-L-A-V-L-D-P-A-M-L-G-D-K-A-D-P-F-A-T-P-L-E-I-L-P-E-W-Y-L-Y-P-V-F-Q-I-L-R-V-V-P-N-K-L-L-G-I-A-L-Q-T-L-V-P-L-G-L-M-L-I-P-F-I-E-S-V-N-K-Y-Q-N-P-F-R-R-P-I-A-M-A-F-F-L-F-G-T-V-I-T-I-Y-L-G-I-G-A-C-L-P-I-D-K-S-L-T-L-G-L-F"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-N-K-S-S-K-K-R-V-Q-I-A-E-R-N-R-L-E-N-K-S-Y-K-S-A-M-R-T-L-M-K-R-C-F-S-A-C-S-H-Y-S-Q-Q-P-G-E-T-A-K-A-N-V-K-A-S-I-D-S-A-F-S-K-I-D-K-A-V-K-R-G-V-L-H-R-N-T-A-A-H-Q-K-S-R-L-S-A-A-V-K-Q-A-I-E-P-A-P-S-T"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-A-V-S-L-S-V-S-T-V-K-P-L-G-D-R-V-F-V-K-V-S-E-S-E-E-K-T-A-G-G-I-L-L-P-D-T-A-K-E-K-P-Q-V-G-E-V-V-Q-V-G-P-G-K-R-N-D-D-G-S-R-Q-A-P-E-V-G-V-G-D-K-V-L-Y-S-K-Y-A-G-T-D-I-K-L-S-T-D-E-Y-V-L-L-S-E-K-D-I-L-A-V-V-N"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-R-D-V-K-R-K-K-I-V-E-R-Y-A-A-K-R-A-A-L-M-E-A-F-N-A-A-K-D-P-M-Q-R-L-E-I-H-R-K-I-Q-A-L-P-R-N-S-A-P-N-R-I-R-N-R-C-W-A-T-G-K-P-R-G-V-Y-R-D-F-G-L-C-R-N-Q-L-R-E-R-A-H-K-G-E-L-P-G-V-V-K-S-S-W"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-S-S-F-F-K-K-R-L-S-P-I-K-P-G-D-P-I-D-Y-K-D-V-D-L-L-K-K-F-I-T-D-R-G-K-I-L-P-R-R-L-T-G-L-T-S-K-Q-Q-R-D-L-T-N-A-V-K-R-A-R-I-I-A-L-L-P-F-V-N-P-E-G"} +{"text": "### FUNCTION Stabilizes the structure of photosystem II oxygen-evolving complex , the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation ### SEQUENCE -M-K-R-L-L-S-L-L-T-G-V-L-V-M-T-G-L-L-M-A-L-I-F-P-Q-S-A-Y-A-N-V-S-D-D-K-L-G-D-R-G-E-K-V-D-L-N-N-S-S-V-R-A-F-R-Q-F-P-G-M-F-P-T-I-A-G-K-I-V-V-G-G-P-Y-A-S-V-S-D-A-S-S-V-L-D-A-S-Q-K-S-V-F-D-K-Y-K-D-N-F-T-V-T-D-Q-E-I-A-V-N-E-G-F-D-R-I-N-D-G-Q-Y-R"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-A-V-S-L-S-V-S-T-V-K-P-L-G-D-R-V-F-I-K-V-S-E-S-E-E-K-T-A-G-G-I-L-L-P-D-T-A-K-E-K-P-Q-V-G-E-V-A-Q-V-G-P-G-K-R-N-D-D-G-S-R-Q-A-P-E-V-G-V-G-D-K-V-L-Y-S-K-Y-A-G-T-D-I-K-L-G-S-D-E-Y-V-L-L-S-E-K-D-I-L-A-V-V-N"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-V-L-P-K-G-M-R-L-K-G-Y-K-S-F-D-Y-I-H-K-S-A-K-R-Y-K-S-D-S-M-M-L-R-V-T-K-A-N-E-R-L-I-K-S-T-I-K-N-S-K-S-N-S-C-R-C-A-I-S-I-S-N-K-V-S-K-K-A-V-I-R-N-R-L-R-R-L-L-H-N-H-L-K-K-R-L-F-Q-K-D-A-F-S-N-N-W-L-L-L-S-L-S-P-K-C-L-D-K-N-T-E-N-L-L-E-E-C-D-K-L-L-I-E-A-G-F-C"} +{"text": "### FUNCTION Structural subunit of pili, which are thin, flexible, coiled-coil, aggregative fibers Mediates adhesion to the extracellular matrix, an event that would facilitate direct interaction with the host epithelium during infection in the lung or other tissues ### SEQUENCE -M-Y-R-F-A-C-R-T-L-M-L-A-A-C-I-L-A-T-G-V-A-G-L-G-V-G-A-Q-S-A-A-Q-T-A-P-V-P-D-Y-Y-W-C-P-G-Q-P-F-D-P-A-W-G-P-N-W-D-P-Y-T-C-H-D-D-F-H-R-D-S-D-G-P-D-H-S-R-D-Y-P-G-P-I-L-E-G-P-V-L-D-D-P-G-A-A-P-P-P-P-A-A-G-G-G-A"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate to provide 4-hydroxybenzoate ### SEQUENCE -M-T-E-C-F-L-S-D-Q-E-I-R-K-L-N-R-D-L-R-I-L-I-A-A-N-G-T-L-T-R-V-L-N-I-V-A-D-D-E-V-I-V-Q-I-V-K-Q-R-I-H-D-V-S-P-K-L-S-E-F-E-Q-L-G-Q-V-G-V-G-R-V-L-Q-R-Y-I-I-L-K-G-R-N-S-E-H-L-F-V-A-A-E-S-L-I-A-I-D-R-L-P-A-A-I-I-T-R-L-T-Q-T-N-D-P-L-G-E-V-M-A-A-S-H-I-E-T-F-K-E-E-A-K-V-W-V-G-D-L-P-G-W-L-A-L-H-G-Y-Q-N-S-R-K-R-A-V-A-R-R-Y-R-V-I-S-G-G-Q-P-I-M-V-V-T-E-H-F-L-R-S-V-F-R-D-A-P-H-E-E-P-D-R-W-Q-F-S-N-A-I-T-L-A-R"} +{"text": "### FUNCTION Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species in vitro, but may act as a sensor of peroxynitrite levels in vivo ### SEQUENCE -M-T-R-D-L-A-P-A-L-Q-A-L-S-P-L-L-G-S-W-A-G-R-G-A-G-K-Y-P-T-I-R-P-F-E-Y-L-E-E-V-V-F-A-H-V-G-K-P-F-L-T-Y-T-Q-Q-T-R-A-V-A-D-G-K-P-L-H-S-E-T-G-Y-L-R-V-C-R-P-G-C-V-E-L-V-L-A-H-P-S-G-I-T-E-I-E-V-G-T-Y-S-V-T-G-D-V-I-E-L-E-L-S-T-R-A-D-G-S-I-G-L-A-P-T-A-K-E-V-T-A-L-D-R-S-Y-R-I-D-G-D-E-L-S-Y-S-L-Q-M-R-A-V-G-Q-P-L-Q-D-H-L-A-A-V-L-H-R-Q-R"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-D-R-K-P-V-R-G-R-H-Q-A-R-K-R-A-V-D-L-L-F-E-A-E-V-R-G-I-S-A-A-E-V-V-D-T-R-A-A-L-A-E-A-K-P-D-I-A-R-L-H-P-Y-T-A-A-V-A-R-G-V-S-E-H-A-A-H-I-D-D-L-I-T-A-H-L-R-G-W-T-L-D-R-L-P-A-V-D-R-A-I-L-R-V-S-V-W-E-L-L-H-A-A-D-V-P-E-P-V-V-V-D-E-A-V-Q-L-A-K-E-L-S-T-D-D-S-P-G-F-V-N-G-V-L-G-Q-V-M-L-V-T-P-Q-L-R-A-A-A-Q-A-V-R-G-G-A"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-D-I-P-S-D-L-H-Y-T-A-E-H-E-W-I-R-R-S-G-D-D-T-V-R-V-G-I-T-D-Y-A-Q-S-A-L-G-D-V-V-F-V-Q-L-P-V-I-G-T-A-V-T-A-G-E-T-F-G-E-V-E-S-T-K-S-V-S-D-L-Y-A-P-I-S-G-K-V-S-A-V-N-S-D-L-D-G-T-P-Q-L-V-N-S-D-P-Y-G-A-G-W-L-L-D-I-Q-V-D-S-S-D-V-A-A-L-E-S-A-L-T-T-L-L-D-A-E-A-Y-R-G-T-L-T-E"} +{"text": "### FUNCTION Copper-sensitive repressor that has a key role in copper homeostasis It is part of the cso operon involved in the cellular response to increasing concentrations of copper inside the bacterium, which can be highly toxic In the presence of copper, CsoR fully dissociates from the promoter in the cso operon, leading to the transcription of its genes Binds to a GC-rich pseudopallindromic sequence, 5'-GTAGCCCACCCCCAGTGGGGTGGGA-3', in the cso promoter region ### SEQUENCE -M-S-K-E-L-T-A-K-K-R-A-A-L-N-R-L-K-T-V-R-G-H-L-D-G-I-V-R-M-L-E-S-D-A-Y-C-V-D-V-M-K-Q-I-S-A-V-Q-S-S-L-E-R-A-N-R-V-M-L-H-N-H-L-E-T-C-F-S-T-A-V-L-D-G-H-G-Q-A-A-I-E-E-L-I-D-A-V-K-F-T-P-A-L-T-G-P-H-A-R-L-G-G-A-A-V-G-E-S-A-T-E-E-P-M-P-D-A-S-N-M"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-L-K-L-H-D-L-R-P-A-R-G-S-K-T-A-R-T-R-V-G-R-G-D-G-S-K-G-K-T-A-G-R-G-T-K-G-T-R-A-R-K-Q-V-P-V-T-F-E-G-G-Q-M-P-I-H-M-R-L-P-K-L-K-G-F-R-N-R-F-R-T-E-Y-E-I-V-N-V-G-D-I-N-R-L-F-P-Q-G-G-A-V-G-V-D-D-L-V-A-K-G-A-V-R-K-N-A-L-V-K-V-L-G-D-G-K-L-T-A-K-V-D-V-S-A-H-K-F-S-G-S-A-R-A-K-I-T-A-A-G-G-S-A-T-E-L"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-T-V-V-P-I-R-I-V-G-D-P-V-L-H-T-A-T-T-P-V-T-V-A-A-D-G-S-L-P-A-D-L-A-Q-L-I-A-T-M-Y-D-T-M-D-A-A-N-G-V-G-L-A-A-N-Q-I-G-C-S-L-R-L-F-V-Y-D-C-A-A-D-R-A-M-T-A-R-R-R-G-V-V-I-N-P-V-L-E-T-S-E-I-P-E-T-M-P-D-P-D-T-D-D-E-G-C-L-S-V-P-G-E-S-F-P-T-G-R-A-K-W-A-R-V-T-G-L-D-A-D-G-S-P-V-S-I-E-G-T-G-L-F-A-R-M-L-Q-H-E-T-G-H-L-D-G-F-L-Y-L-D-R-L-I-G-R-Y-A-R-N-A-K-R-A-V-K-S-H-G-W-G-V-P-G-L-S-W-L-P-G-E-D-P-D-P-F-G-H"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-F-R-P-L-G-E-R-V-L-V-E-R-V-E-E-D-T-K-T-S-S-G-I-I-I-P-D-N-A-K-E-K-P-L-M-G-I-V-K-A-V-S-A-K-I-K-D-D-K-I-L-K-E-N-D-K-V-V-F-G-K-Y-K-G-A-E-I-K-L-D-S-K-E-F-I-V-L-E-L-D-D-I-L-G-V-I-E-K"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-D-T-N-K-I-Q-G-D-K-P-I-M-N-V-E-K-I-R-Q-I-L-P-H-R-Y-P-M-L-L-V-D-R-V-M-E-L-V-Q-N-T-S-D-S-E-P-N-G-Y-I-K-A-Y-K-N-V-T-I-N-E-E-V-F-L-G-H-F-P-N-K-P-I-Y-P-G-V-M-Q-I-E-G-M-A-Q-A-G-G-L-L-A-F-V-S-M-F-G-D-N-V-A-E-A-K-N-K-I-V-Y-F-M-T-I-D-N-V-K-F-R-I-P-V-V-P-G-D-R-L-V-Y-E-L-K-V-L-K-H-K-G-S-I-W-Q-L-G-A-N-A-F-V-E-D-K-L-V-S-E-A-E-L-K-A-M-I-T-E-A-K-E-S"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-I-R-P-L-H-D-R-V-I-V-K-R-K-E-V-E-S-K-S-S-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-E-V-L-A-V-G-H-G-R-V-L-E-N-G-G-I-K-A-L-D-V-R-V-G-D-T-I-I-F-N-D-G-Y-G-V-K-V-E-K-I-D-N-E-E-V-L-I-M-S-E-N-D-I-L-A-I-V-E-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-T-L-D-P-Y-Y-E-T-M-Y-I-L-R-P-D-I-P-E-E-E-V-E-S-H-L-T-K-Y-R-D-M-L-V-E-A-G-A-D-V-L-D-N-Q-M-R-G-K-R-R-L-A-Y-P-I-D-K-H-K-E-G-I-Y-V-Q-L-S-H-N-G-D-G-Q-Q-V-A-V-L-E-K-A-M-R-L-S-E-D-V-I-R-Y-L-T-V-K-Q-E-G-P-L-P-A-P-R-V-V-P-G-S-E-P-A-A-A-P-Q-E-Q-P-A-A-N-S-E-A-A-S"} +{"text": "### FUNCTION Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide ### SEQUENCE -M-T-V-M-S-L-T-A-T-L-M-A-A-K-K-A-K-G-M-S-F-A-D-L-E-A-A-I-G-L-D-E-V-W-V-A-S-L-F-Y-G-Q-A-T-A-S-K-E-E-A-E-K-L-A-G-L-L-S-L-D-A-E-T-T-A-A-L-Q-E-Y-P-T-K-G-S-L-E-P-V-I-P-T-D-P-L-I-Y-R-F-Y-E-I-M-Q-V-Y-G-M-P-L-K-D-V-I-Q-E-H-F-G-D-G-I-M-S-A-I-D-F-T-I-D-V-D-K-V-E-D-P-K-G-D-R-V-K-I-V-M-C-G-K-F-L-P-Y-K-K-W"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-T-Q-A-V-L-V-L-D-Q-R-L-A-A-R-A-D-Q-A-D-L-L-L-P-L-T-A-D-E-R-S-V-V-R-G-R-R-R-T-D-C-G-R-E-V-L-L-Q-L-P-R-D-G-A-L-Q-P-G-D-Q-L-S-D-A-A-G-T-A-R-V-E-V-T-A-A-T-E-A-L-L-R-V-R-A-T-S-A-L-A-L-M-Q-A-A-Y-H-L-G-N-R-H-V-A-L-E-L-H-E-Q-D-L-Y-L-L-E-D-A-V-L-A-T-M-L-E-S-R-G-L-Q-L-S-R-C-Q-R-P-F-R-P-E-G-G-A-Y-A-G-H-Q-H-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-P-K-R-V-Q-V-V-L-N-E-D-V-L-S-L-G-K-D-G-D-L-V-E-V-A-P-G-Y-A-R-N-F-L-L-P-F-G-K-A-V-P-V-T-P-A-V-M-K-Q-V-E-H-R-R-A-K-E-A-E-R-Q-A-A-L-K-Q-A-A-L-D-F-R-T-A-L-D-T-I-G-R-F-T-V-K-K-Q-T-G-E-D-N-V-L-F-G-T-V-T-N-G-D-V-A-E-A-I-Q-D-A-T-K-K-E-I-D-R-R-D-I-V-V-P-E-I-H-R-T-G-K-Y-S-V-T-V-K-L-H-S-E-V-T-A-E-I-N-L-E-V-V-S-Y"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-T-A-V-I-K-L-A-L-Q-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-M-F-C-K-E-Y-N-A-R-T-Q-D-K-A-G-F-V-I-P-V-E-I-S-V-Y-E-D-R-S-F-T-F-I-T-K-T-P-P-A-S-V-L-I-T-K-A-A-K-I-E-K-G-S-G-E-S-A-K-G-N-V-G-S-I-N-R-A-Q-L-E-E-I-A-K-T-K-L-P-D-L-N-C-T-S-V-E-S-A-M-R-I-I-E-G-T-A-R-N-M-G-V-S-I-S-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-G-R-T-L-E-S-K-Q-Q-I-V-G-E-L-K-E-L-L-A-E-S-E-L-A-L-V-L-D-Y-K-G-L-S-I-K-E-M-S-D-L-R-D-R-L-R-A-G-N-A-V-C-K-V-T-K-N-T-L-M-R-R-A-I-D-G-D-S-A-W-S-N-L-D-S-L-L-T-G-T-N-A-F-V-L-I-K-G-D-V-G-A-G-V-K-A-V-Q-A-F-Q-K-E-T-K-K-S-E-T-K-G-G-L-F-E-G-K-L-L-S-Q-D-E-I-K-A-I-A-D-L-P-S-K-E-Q-L-M-A-Q-I-A-G-A-I-N-A-V-A-T-K-V-A-V-G-I-N-E-V-P-S-G-L-A-R-A-L-K-Q-H-A-E-G-G-D-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-A-K-T-D-E-I-L-E-S-L-K-S-L-S-L-L-E-A-S-E-L-V-K-Q-I-E-E-A-F-G-V-S-A-A-A-S-A-G-V-V-M-A-A-P-G-A-A-A-G-G-G-G-G-E-V-A-E-E-K-T-E-F-D-V-I-L-E-S-F-D-A-A-A-K-I-K-V-L-K-A-V-R-N-A-T-G-L-G-L-G-D-A-K-A-L-V-E-A-A-P-K-P-I-K-E-G-I-S-K-D-E-A-E-A-L-K-K-E-I-E-E-V-G-G-K-V-T-L-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-E-L-D-L-A-L-D-A-A-G-P-W-S-P-E-D-P-S-S-L-I-E-T-Q-T-W-Q-I-T-L-V-D-W-I-Q-T-I-C-A-D-P-S-L-P-C-P-A-L-V-C-Q-A-D-E-V-S-L-G-L-R-F-T-D-D-A-T-I-T-A-L-N-S-T-W-R-Q-R-N-Q-A-T-D-V-L-S-F-A-A-L-E-E-A-P-G-L-P-D-V-S-C-V-E-L-G-D-I-V-I-S-L-D-T-A-R-R-Q-A-S-E-H-G-H-N-L-T-R-E-L-R-W-L-V-S-H-G-L-L-H-L-L-G-W-D-H-P-D-E-E-S-L-V-A-M-L-Q-L-Q-E-Q-L-L-D-G-G-S-N-V-R-I-R-D-P-H-S-V-D-T-T-V-D-V-N-A-H"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA biosynthesis ### SEQUENCE -M-T-S-P-D-H-W-L-K-L-E-R-Q-V-H-F-G-D-T-D-A-A-G-V-M-H-F-H-Q-L-L-R-W-C-H-E-A-W-E-E-S-L-E-R-Y-G-I-A-A-G-S-V-F-P-G-C-R-G-Q-Q-R-W-P-A-V-A-L-P-V-V-H-C-Q-A-D-F-K-R-P-V-H-G-S-D-R-L-Q-V-H-L-K-P-Q-R-L-D-P-G-C-F-E-V-R-S-E-F-H-L-D-A-T-V-M-A-C-G-L-V-R-H-L-A-I-H-S-D-S-R-E-R-C-A-L-P-E-T-V-D-L-W-L-E-A-S-A-L-G-Q-I-T-S-L"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-A-D-T-L-L-K-C-T-T-R-H-V-R-L-F-T-A-R-V-D-N-Q-D-L-V-P-S-A-D-E-L-T-L-D-L-D-P-D-N-E-F-L-W-S-D-A-V-V-S-K-V-Q-Q-R-F-Q-Q-L-V-E-A-G-A-G-G-E-L-S-D-Y-S-L-R-R-I-G-T-D-L-E-G-Y-I-R-Q-L-L-Q-A-G-E-L-S-Y-N-P-D-G-R-V-Q-N-F-S-M-G-L-P-R-T-P-D-L-L"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-N-R-N-D-N-F-I-D-K-S-F-T-V-M-A-D-L-I-V-K-L-L-P-I-N-A-R-S-K-E-A-Y-V-Y-Y-R-D-G-L-S-A-Q-N-D-G-D-Y-A-E-A-L-E-N-Y-D-E-A-L-K-L-E-D-N-P-T-D-R-G-E-T-L-K-N-M-A-I-I-Y-M-S-N-G-E-E-E-R-A-I-E-T-Y-R-R-A-L-D-E-N-S-N-Q-P-S-C-L-K-N-M-G-L-I-F-E-K-W-G-R-I-A-E-E-D-G-R-Q-D-D-A-D-R-W-F-D-Q-A-A-E-A-W-T-Q-A-V-R-L-N-P-G-G-Y-L-D-I-E-N-W-L-K-S-T-G-R-S-N-V-D-V-Y-F"} +{"text": "### FUNCTION Stabilizes the structure of photosystem II oxygen-evolving complex , the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation ### SEQUENCE -M-K-R-L-L-S-W-L-T-G-A-L-L-M-A-G-L-L-A-G-L-I-L-P-G-S-V-H-A-D-E-D-L-V-G-K-Y-S-G-N-E-I-R-N-I-A-D-D-K-I-A-A-R-E-G-K-V-D-L-N-N-S-S-V-R-R-F-Q-Q-F-P-G-M-Y-P-T-M-A-G-K-I-V-L-G-G-P-Y-N-D-V-D-E-V-L-N-L-D-L-S-E-R-Q-I-E-L-F-N-K-Y-K-E-N-F-T-V-T-P-P-E-I-A-L-N-E-G-D-D-R-I-N-D-G-Q-Y-R"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-T-A-I-A-Q-Q-K-I-R-I-R-L-K-A-F-D-R-R-M-L-D-L-S-C-D-K-I-I-E-T-A-D-Q-T-A-A-T-A-I-G-P-I-P-L-P-T-K-R-K-I-Y-C-V-L-R-S-P-H-V-D-K-D-S-R-E-H-F-E-T-R-T-H-R-R-I-I-D-I-Y-S-P-S-A-K-T-I-D-A-L-M-K-L-D-L-P-S-G-V-D-I-E-V-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-N-A-A-E-K-R-P-V-L-P-D-P-Q-F-N-S-R-L-A-T-M-M-V-S-R-L-M-Q-H-G-K-K-S-T-A-Q-R-I-L-S-D-A-F-G-L-I-N-E-R-T-G-G-D-P-L-E-L-F-E-T-A-V-K-N-A-T-P-L-V-E-V-R-A-R-R-V-G-G-A-T-Y-Q-V-P-M-E-V-R-Q-E-R-G-T-A-M-A-L-R-W-L-V-S-F-S-R-A-R-N-G-R-S-M-A-Q-K-L-A-G-E-L-M-D-A-A-N-E-A-G-S-A-V-R-K-R-E-E-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-Y"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-P-K-P-D-I-H-P-T-W-Y-P-D-A-K-V-I-C-N-G-E-V-V-M-T-T-G-S-T-Q-P-E-I-H-V-D-V-W-S-G-N-H-P-F-F-T-G-T-Q-K-I-L-D-T-E-G-R-V-D-R-F-M-K-K-Y-G-M-G-Q-K-K-S-G-D-K-A-K-A-E-A-K-A-D-A-K-S"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-N-K-T-S-L-P-Q-I-D-S-L-E-R-Q-W-Y-L-V-D-A-E-N-K-T-L-G-R-L-A-T-E-V-A-A-V-L-R-G-K-N-N-P-S-F-T-P-H-L-D-T-G-D-F-V-V-V-V-N-A-E-K-I-R-V-S-G-S-K-P-T-Q-K-L-Y-R-R-H-S-G-R-P-G-G-M-K-T-E-T-F-E-A-L-Q-D-R-I-P-E-R-I-V-E-K-A-I-K-G-M-L-P-H-N-A-L-G-R-Q-M-F-R-K-L-K-V-Y-K-G-S-E-H-P-H-A-A-Q-K-P-Q-P-L-Q-L-N-P-S-A-S-A-Q"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-P-A-K-K-T-G-P-K-K-A-K-R-N-V-P-N-G-V-A-H-I-Q-S-T-F-N-N-T-I-V-S-I-T-D-T-S-G-E-V-I-S-W-S-S-A-G-A-S-G-F-K-G-A-R-K-G-T-P-F-A-A-Q-T-A-A-E-A-A-A-R-R-A-L-D-Q-G-M-R-Q-I-E-V-L-V-K-G-P-G-S-G-R-E-T-A-I-R-A-L-Q-V-A-G-L-E-I-T-L-I-R-D-V-T-P-L-P-H-N-G-C-R-R-P-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-I-P-R-D-K-R-V-E-V-S-L-T-Y-I-Y-G-V-G-P-T-R-A-R-T-I-L-A-Q-T-G-V-S-P-D-I-R-V-K-D-L-E-D-G-D-L-Q-K-L-R-N-A-A-D-D-F-T-L-E-G-D-L-R-R-Q-E-G-M-A-L-K-R-L-Q-D-I-G-C-V-R-G-R-R-H-R-M-S-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-R-G-A-R-K-T-V-A-G-K-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-T-L-R-L-E-S-L-K-A-N-K-G-A-R-R-R-K-L-R-K-G-R-G-I-A-A-G-Q-G-A-S-C-G-F-G-M-R-G-Q-K-S-R-S-G-R-P-T-R-P-G-F-E-G-G-Q-M-P-L-Y-R-R-V-P-K-L-K-H-F-P-L-V-N-P-K-H-F-T-V-L-N-V-S-A-L-N-S-L-K-D-G-S-T-V-N-L-D-S-L-V-K-D-G-V-V-T-S-P-K-H-P-L-K-I-L-G-N-G-D-L-T-A-K-K-L-T-V-Q-A-A-A-F-T-A-S-A-R-T-K-I-E-A-A-G-G-S-C-E-T-L-D"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-K-L-S-R-K-Q-Q-T-Q-K-R-H-R-R-L-R-R-H-L-T-G-T-S-D-R-P-R-L-A-V-F-R-S-N-N-H-I-Y-A-Q-V-I-D-D-D-A-Q-S-T-L-C-S-A-S-T-V-D-K-E-L-R-A-G-L-E-A-N-G-G-S-C-D-A-S-V-A-V-G-E-L-V-A-K-R-A-I-A-K-G-I-Q-S-V-V-F-D-R-G-G-N-L-Y-H-G-R-I-K-A-L-A-D-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-N-P-V-P-V-P-D-K-V-T-V-S-L-D-G-L-T-V-K-V-K-G-P-K-G-E-L-E-R-T-L-P-D-G-V-S-V-S-Q-D-N-N-C-I-V-V-A-P-S-T-S-K-R-F-S-R-E-R-H-G-L-C-R-T-L-V-A-N-M-I-E-G-V-N-N-G-Y-S-K-S-L-E-I-V-G-V-G-S-R-A-Q-V-K-G-K-T-L-V-V-S-A-G-Y-S-H-P-V-E-M-E-P-P-E-G-I-T-F-K-V-E-N-N-T-K-V-I-V-S-G-I-D-K-E-L-V-G-N-E-A-A-K-V-R-A-I-R-P-P-E-P-Y-K-G-K-G-I-K-Y-E-G-E-R-I-M-R-K-A-G-K-S-G-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-A-N-H-D-P-I-S-D-M-L-T-R-I-R-N-A-S-E-K-R-H-E-T-T-K-I-P-A-S-R-M-T-R-S-I-A-K-V-L-Q-Q-E-G-F-I-S-E-I-S-E-Q-G-E-G-V-R-T-E-L-V-L-S-L-K-Y-S-G-K-H-R-L-P-T-I-R-S-M-Q-R-V-S-K-P-G-L-R-I-Y-K-N-T-R-G-L-P-K-V-L-G-G-L-G-V-A-I-I-S-T-S-K-G-V-M-S-D-R-D-A-R-R-E-G-V-G-G-E-V-L-C-Y-V-Y"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-L-K-K-R-Y-R-E-T-I-Q-P-K-L-Q-K-D-L-S-L-T-N-I-H-E-V-P-K-V-V-K-V-T-V-N-R-G-L-G-E-A-A-A-N-A-K-S-L-E-A-S-V-N-E-L-A-Q-I-T-G-Q-K-V-V-V-T-R-A-K-K-A-I-A-A-F-K-I-R-Q-G-M-P-I-G-C-A-V-T-L-R-G-D-R-M-Y-A-F-L-E-R-L-I-N-L-A-L-P-R-I-R-D-F-R-G-V-S-P-K-S-F-D-G-R-G-N-Y-T-L-G-V-R-E-Q-I-I-F-P-E-I-S-F-D-K-I-D-A-I-R-G-M-D-I-T-I-V-T-T-A-R-S-D-E-E-G-R-A-L-L-R-E-M-G-M-P-F-Q-S-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-T-A-T-S-K-A-K-P-S-D-R-I-K-M-R-I-R-K-G-D-T-V-Q-V-I-A-G-K-D-K-G-K-T-G-E-V-L-R-T-L-P-N-E-N-R-L-I-V-E-G-V-N-M-R-T-R-H-E-K-P-T-Q-E-G-E-T-G-R-I-V-N-E-E-A-S-L-H-A-S-N-V-M-L-Y-S-T-A-K-K-V-A-S-R-V-E-I-V-V-E-K-D-G-S-K-K-R-K-L-K-K-T-G-E-V-L-D"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-Y-L-S-V-A-D-N-S-G-A-K-R-I-Q-C-I-R-V-L-G-T-N-R-R-Y-A-H-V-G-D-V-I-V-A-A-V-K-D-A-M-P-N-M-G-V-K-K-S-D-V-V-K-A-V-V-V-R-T-K-A-T-L-R-R-D-T-G-N-S-I-R-F-D-D-N-A-A-V-I-I-N-A-D-N-N-P-K-G-T-R-V-F-G-P-V-A-R-E-L-R-E-R-N-F-T-K-I-V-S-L-A-P-E-V-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-V-K-E-R-V-G-T-V-V-S-D-K-M-E-K-T-V-V-V-A-V-E-S-R-F-P-H-P-I-Y-Q-K-T-V-S-R-T-T-R-Y-K-A-H-D-E-D-N-S-C-R-V-G-D-R-V-R-I-T-E-T-R-P-M-S-R-H-K-R-W-A-I-A-E-V-L-S-H-S-P-K-A-D-K-S-A-G-S-T-A-P-A-P-E-A-A-A-K-E-V-S-E"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-S-P-K-R-V-K-F-R-K-M-Q-R-G-R-M-R-G-V-A-T-R-G-N-T-I-A-F-G-E-F-A-L-Q-A-Q-E-C-G-W-I-T-S-R-Q-I-E-A-S-R-R-A-M-T-R-Y-V-K-R-G-G-K-I-W-I-R-I-F-P-D-K-S-I-T-M-R-A-A-E-T-R-M-G-S-G-K-G-N-P-E-F-W-V-A-V-I-K-P-G-R-I-L-F-E-M-G-G-A-E-I-T-P-E-I-A-K-E-A-M-R-L-A-Q-Y-K-L-P-V-K-T-K-F-I-A-L-D-E-Q-Q-K-Q-S-A-A-E-A-P-A-A-A-E-A-V-N-V-E-S"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-T-T-S-S-T-T-A-P-I-A-Q-A-H-G-R-F-I-R-G-S-V-S-K-V-R-R-V-L-D-Q-I-R-G-R-T-Y-R-D-A-L-I-M-L-E-F-M-P-Y-R-S-T-G-P-I-T-K-V-L-R-S-A-V-A-N-A-E-H-N-L-G-L-D-P-A-S-L-V-I-S-S-A-S-A-D-M-G-P-S-M-K-R-Y-R-P-R-A-Q-G-R-A-F-Q-I-K-K-Q-T-C-H-I-S-I-A-V-A-A-Q-P-D-S"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-I-A-D-S-L-L-R-K-V-E-K-Q-N-D-T-D-D-K-S-V-I-K-T-W-S-R-A-S-T-I-L-P-M-M-I-G-H-T-I-A-V-H-N-G-K-S-H-V-P-V-F-I-T-E-Q-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-K-G-H-I-K-D-K-K-G-G-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-E-R-F-Q-G-R-L-A-D-V-I-R-R-P-L-I-T-E-K-A-T-R-A-L-E-F-N-Q-Y-T-F-E-V-D-H-R-A-A-K-P-D-I-K-A-A-I-E-Q-L-F-D-V-K-V-T-G-I-S-T-M-N-P-P-R-R-T-R-R-M-G-R-F-A-G-K-R-A-Q-V-K-K-A-V-V-R-L-A-E-G-N-S-I-Q-L-F-P-E-S"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-P-L-L-L-T-G-R-T-F-R-R-D-L-E-A-H-G-C-L-A-V-H-A-P-L-E-G-G-A-E-T-R-L-L-R-R-L-R-G-A-G-Y-R-T-R-L-W-S-A-R-G-L-G-D-P-E-V-F-L-T-Q-K-H-G-I-R-P-P-H-L-G-H-Q-S-V-G-R-G-A-A-V-G-E-V-Q-E-V-V-P-Q-L-G-D-L-L-D-G-D-A-Q-V-A-L-W-L-L-E-G-Q-V-L-S-Q-S-E-L-R-S-L-C-D-L-C-S-R-E-P-R-L-R-I-I-V-E-M-G-G-A-R-S-L-R-W-Q-P-M-S-G-L-L-A-S"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Q-C-P-S-Y-Q-N-T-D-S-R-V-L-E-S-R-A-A-D-G-G-R-S-V-R-R-R-R-E-C-L-N-C-E-F-R-F-T-T-Y-E-R-V-E-T-V-P-I-T-V-I-K-R-N-G-N-R-E-I-F-S-R-S-K-L-L-H-G-L-N-R-A-C-E-K-T-G-L-D-A-S-R-L-E-T-L-V-E-E-L-E-L-K-L-Q-Q-R-S-G-R-E-V-S-S-A-E-I-G-E-L-V-L-V-E-L-K-Q-M-S-E-V-A-Y-I-R-F-A-S-V-Y-R-Q-F-Q-G-I-D-D-F-V-S-T-L-E-T-M-N-R-K-A-G-P-G-H-L-A-A-V-G"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-S-F-A-Y-V-L-I-L-T-L-A-I-A-T-L-F-F-A-I-A-F-R-D-P-P-K-I-G-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-T-N-D-L-G-F-V-A-S-L-L-F-I-L-V-P-A-I-F-L-I-V-L-Y-I-G-T-N-R-S-E-S"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-T-L-Q-D-L-I-D-K-L-L-G-R-Q-P-A-S-A-D-T-A-R-Q-R-L-Q-L-V-L-A-H-D-R-S-D-L-N-P-E-L-L-D-Q-M-R-R-E-I-L-E-V-V-S-R-Y-V-E-I-D-L-S-E-G-D-V-S-L-E-T-E-D-R-V-T-A-L-V-A-N-L-P-I-R-R-T-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-H-I-L-K-K-P-D-L-S-D-P-K-M-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-V-V-I-L-G-T-I-A-C-I-V-G-L-A-V-L-D-P-A-M-L-A-D-K-A-D-P-F-A-T-P-L-E-I-L-P-E-W-Y-L-Y-P-V-F-Q-I-L-R-V-V-P-N-K-L-L-G-I-A-L-Q-T-L-V-P-L-G-L-M-L-V-P-F-I-E-S-F-N-K-F-Q-N-P-F-R-R-P-V-A-M-T-V-F-L-F-G-T-V-T-T-I-Y-L-G-I-G-A-A-L-P-I-D-K-S-L-T-L-G-L-F"} +{"text": "### FUNCTION Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase ### SEQUENCE -M-A-I-S-R-G-A-K-V-R-I-K-R-P-E-S-Y-W-F-N-E-V-G-T-V-A-S-I-D-T-S-G-I-R-Y-P-V-V-V-R-F-E-K-V-N-Y-T-G-I-D-G-T-D-G-G-V-N-T-N-N-F-S-E-A-E-L-E-L-A"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-R-D-V-K-R-K-K-M-A-E-R-Y-A-A-K-R-A-A-L-M-A-A-F-N-A-A-D-D-P-M-D-R-L-E-I-H-R-K-I-Q-A-L-P-R-N-S-A-P-S-R-I-R-N-R-C-W-A-T-G-K-P-R-G-Y-Y-R-D-F-G-L-C-R-N-Q-L-R-E-R-A-H-K-G-E-L-P-G-V-V-K-S-S-W"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-A-L-P-A-S-M-R-L-R-G-H-R-C-F-N-R-L-H-R-I-G-R-R-H-H-G-D-W-M-V-L-R-V-M-P-E-E-P-R-L-L-R-P-E-L-R-R-H-P-T-R-C-C-R-C-A-L-V-I-S-S-K-V-S-K-R-A-V-R-R-N-R-L-R-R-L-L-H-Q-H-L-R-Q-Q-L-E-H-R-G-D-L-A-G-R-W-V-L-I-S-L-R-P-E-A-S-E-A-E-P-S-Q-L-L-E-E-C-D-S-L-L-S-S-A-G-L-G-Q"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-Q-K-F-L-T-T-A-P-V-V-A-A-I-W-F-T-L-T-A-G-I-L-I-E-W-N-R-F-F-P-D-L-L-F-H-P-M"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-A-A-D-P-K-D-T-T-V-T-D-E-N-T-E-T-A-A-T-A-E-V-E-T-V-A-S-A-P-T-S-P-A-Q-K-L-S-A-E-A-L-I-K-A-F-E-T-E-Q-M-K-S-D-L-P-E-I-Y-V-G-D-T-V-R-V-G-V-R-I-S-E-G-N-K-E-R-V-Q-P-Y-E-G-V-V-I-S-K-R-H-G-G-M-N-Q-T-I-T-V-R-R-I-F-Q-G-I-G-V-E-R-V-F-M-L-H-S-P-Q-V-A-N-I-K-V-E-R-R-G-K-V-R-R-A-K-L-F-Y-L-R-E-R-V-G-K-A-T-R-V-K-Q-R-F-D-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-T-Q-D-L-E-A-S-M-R-K-S-V-E-A-T-Q-R-N-F-N-T-I-R-T-G-R-A-N-S-S-L-L-D-R-I-S-V-E-Y-Y-G-A-E-T-P-L-K-S-L-A-T-L-S-T-P-D-S-Q-T-I-Q-I-Q-P-F-D-I-S-A-L-A-S-I-E-K-A-I-A-M-S-E-L-G-F-T-P-N-N-D-G-K-I-I-R-I-N-V-P-P-L-T-E-E-R-R-K-E-F-C-K-L-A-S-K-Y-A-E-E-G-K-V-A-L-R-N-L-R-R-D-A-I-D-K-V-K-K-Q-E-K-D-G-D-F-S-E-D-Q-S-R-D-E-Q-D-A-V-Q-K-T-L-D-K-F-I-A-E-L-E-K-H-L-A-D-K-E-A-D-I-L-K-V"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-L-L-L-A-S-A-S-P-A-R-L-R-L-L-E-L-A-Q-I-P-H-R-V-R-V-S-G-V-D-E-S-S-I-E-N-H-D-P-A-L-L-V-Q-Q-L-A-L-A-K-A-T-A-V-S-D-G-I-D-A-D-I-S-S-V-L-G-C-D-S-L-L-L-F-E-G-E-V-F-G-K-P-Q-D-G-E-E-A-A-A-R-W-R-R-M-A-G-G-S-G-E-L-L-T-G-H-A-L-L-V-R-S-G-E-N-R-L-A-C-I-S-T-R-V-H-F-A-A-I-T-E-E-E-I-Q-A-Y-V-T-T-G-E-P-L-H-C-A-G-G-F-A-L-E-G-R-G-A-S-L-I-A-G-L-E-G-C-Y-S-N-V-I-G-L-S-L-P-W-L-R-S-V-L-R-D-S-K-M-D-Q-S-A-S-G"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-P-I-G-T-P-S-V-P-Y-R-L-P-G-S-Q-M-E-R-W-V-D-I-Y-T-R-L-G-V-E-R-I-L-F-L-G-S-E-V-N-D-G-I-A-N-S-L-V-A-Q-M-L-Y-L-D-S-E-D-S-S-K-P-I-Y-L-Y-I-N-S-P-G-G-S-V-T-A-G-L-A-I-Y-D-T-I-Q-Y-V-K-S-E-V-V-T-I-C-V-G-L-A-A-S-M-G-A-F-L-L-A-A-G-T-K-G-K-R-V-A-L-P-H-S-R-I-M-I-H-Q-P-L-G-G-T-S-R-R-Q-A-S-D-I-E-I-E-A-R-E-I-L-R-M-K-E-M-L-N-R-S-L-S-D-M-S-G-Q-S-F-D-K-I-E-K-D-T-D-R-D-Y-F-L-S-A-E-E-A-K-D-Y-G-L-I-D-R-V-I-S-H-P-N-E-A"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-L-F-T-V-A-W-A-S-L-A-A-M-F-S-F-S-I-A-M-V-V-W-G-R-N-G-D-G-T-L-N-F"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-I-P-I-V-I-E-E-S-G-R-G-E-R-A-F-D-I-Y-S-R-L-L-R-E-R-I-I-F-L-G-E-A-V-T-S-D-S-A-N-R-I-V-A-Q-M-L-F-L-E-A-E-D-P-E-K-D-I-Y-L-Y-I-N-S-P-G-G-S-V-Y-D-G-L-G-I-F-D-T-M-Q-H-I-K-P-D-V-H-T-V-C-V-G-L-A-A-S-M-G-A-F-L-L-C-A-G-T-K-G-K-R-S-S-L-Q-H-S-R-I-M-I-H-Q-P-L-G-G-A-R-G-Q-A-S-D-I-R-I-Q-A-D-E-I-L-Y-L-K-E-R-L-N-Q-E-L-S-D-R-T-G-Q-P-L-D-R-I-Q-Q-D-T-D-R-D-F-F-M-S-P-G-E-A-V-E-Y-G-L-I-D-S-V-I-D-K-R-P-I-Q-A-V-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-S-S-F-F-K-K-R-L-S-P-I-K-P-G-D-P-I-D-Y-K-D-V-D-L-L-K-K-F-I-T-E-R-G-K-I-L-P-R-R-L-T-G-L-T-A-K-Q-Q-R-D-L-T-N-A-V-K-R-A-R-I-V-A-L-L-P-F-V-N-P-E-G"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-N-P-S-R-C-R-I-L-A-V-G-K-V-R-R-S-W-I-Q-D-G-I-E-L-Y-R-K-R-L-P-G-L-E-I-I-E-I-R-D-S-T-P-D-K-E-A-D-S-I-R-A-S-L-R-P-N-E-H-V-I-A-L-M-E-E-G-D-A-V-G-S-I-P-F-A-R-R-L-D-Q-L-G-N-Q-R-L-A-F-V-I-G-G-A-D-G-L-T-N-E-L-K-G-R-A-H-W-Q-L-S-L-S-P-M-T-F-P-H-E-L-A-R-L-M-L-I-E-Q-L-F-R-A-Q-A-I-L-Q-G-S-P-Y-H-R-A"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-A-R-L-I-D-Q-F-E-R-L-P-G-I-G-P-R-T-A-Q-R-L-A-L-H-L-L-N-Q-P-E-E-Q-I-R-Q-F-A-D-A-L-L-A-A-R-T-Q-V-G-Q-C-Q-T-C-F-H-L-S-A-D-P-E-C-E-I-C-R-N-P-E-R-R-N-G-L-I-C-V-V-A-D-S-R-D-L-L-A-L-E-R-T-R-E-F-Q-G-R-Y-H-V-L-G-G-L-I-S-P-M-D-G-I-G-P-E-L-L-H-V-T-P-L-V-A-R-I-N-Q-E-D-I-T-E-V-I-L-A-L-T-P-S-V-E-G-D-T-T-S-L-Y-L-A-R-L-L-K-P-F-C-P-V-S-R-I-A-Y-G-L-P-M-G-S-E-L-E-Y-A-D-E-V-T-L-S-R-A-L-E-G-R-R-P-L-D"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-R-P-C-S-V-L-S-L-D-V-G-R-K-R-I-G-L-A-G-C-D-P-L-G-I-T-V-T-P-I-K-A-L-H-R-G-R-F-D-D-D-L-P-V-L-Q-Q-L-C-Q-D-R-R-V-Q-G-L-V-V-G-L-P-L-D-A-A-G-Q-P-T-A-Q-A-D-H-C-L-R-Y-G-R-R-L-A-Q-A-L-Q-L-P-L-A-W-V-N-E-H-S-S-T-W-A-A-G-E-R-H-G-L-K-G-D-R-S-G-R-L-D-S-A-A-A-A-L-L-L-D-Q-W-L-R-E-G-P-D-L-K-P-V-Q-G-L-L-G-G-A-G-A-E-L-V-D-G-G-S"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-I-E-P-L-L-C-G-I-V-L-G-L-I-P-V-T-L-L-G-L-F-V-A-A-W-N-Q-Y-R-R-G-G-S-A-L-G-G"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-S-A-E-V-L-E-Q-P-V-L-G-S-R-R-L-S-N-Y-L-V-A-A-A-V-S-I-G-G-I-G-F-L-L-A-S-L-S-S-Y-L-G-R-D-L-L-P-L-G-H-P-A-A-L-I-F-V-P-Q-G-L-V-M-G-L-Y-S-I-A-A-A-L-L-A-T-Y-L-W-Y-V-I-A-V-D-V-G-G-G-S-N-R-F-D-K-A-A-G-V-V-T-V-S-R-R-G-F-R-K-P-V-L-V-E-I-P-L-K-D-V-K-A-V-K-V-E-V-R-D-G-F-N-A-R-R-R-V-A-L-R-I-Q-G-R-R-D-M-P-L-T-R-V-G-E-P-L-P-L-A-Q-L-E-Q-D-G-A-E-L-A-R-F-L-G-V-N-L-E-G-L"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-L-I-S-R-L-R-A-V-V-A-G-D-D-Y-L-D-G-D-L-D-D-L-V-Y-D-D-D-Q-P-E-Q-D-Q-R-A-S-Q-A-D-G-G-A-L-A-T-I-G-D-G-N-P-F-D-L-G-D-N-F-S-G-S-N-V-I-G-M-P-G-I-S-T-A-A-A-E-V-N-L-M-E-P-R-S-F-D-E-M-P-R-A-I-Q-A-L-R-E-R-K-T-V-I-L-N-L-T-M-M-E-P-D-Q-A-Q-R-A-V-D-F-V-A-G-G-T-F-A-I-D-G-H-Q-E-R-V-G-E-S-I-F-L-F-A-P-S-C-V-T-V-T-N-T-S-H-D-E-A-S-T-P-T-V-V-S-R-D-A-E-A-E-Q-Q-Q-E-A-A-A-A-P-S-P-A-W-G-A-T-A-L"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-N-Q-A-A-K-K-R-I-E-I-A-E-R-N-R-L-R-N-R-T-Y-K-S-A-L-R-T-L-M-K-R-C-F-V-A-C-E-A-Y-S-K-E-P-G-D-A-A-K-A-T-V-S-A-S-M-N-A-A-F-S-K-I-D-K-A-V-K-V-G-V-L-H-R-N-N-G-A-H-Q-K-S-R-L-S-A-T-V-R-Q-V-L-E-P-S-S"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-P-H-P-L-L-P-E-L-E-T-L-A-T-S-V-A-A-D-Q-G-F-E-L-C-G-I-Q-L-L-T-H-L-A-P-M-T-L-E-V-H-I-R-R-S-N-G-V-D-V-N-M-D-D-C-A-G-F-S-G-T-L-G-E-A-L-E-S-A-Q-L-L-T-E-A-Y-V-L-E-I-S-S-P-G-I-G-E-T-L-S-S-D-R-D-F-Q-T-F-R-G-F-P-V-E-V-V-H-R-D-R-D-D-T-E-Q-R-L-E-G-L-L-L-E-R-D-E-D-T-L-Q-I-N-I-R-G-R-I-K-R-L-P-R-D-H-V-L-S-V-R-L-T-S-P-G-S"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-T-D-S-P-A-S-D-A-A-Q-S-S-V-V-L-T-S-E-Q-I-A-G-L-L-P-H-R-Y-P-F-A-L-V-D-R-V-I-A-H-E-P-G-V-S-A-T-G-I-K-N-V-T-V-N-E-P-Q-F-Q-G-H-F-P-G-R-P-L-M-P-G-V-L-I-V-E-A-M-A-Q-V-G-G-L-I-V-T-Q-M-P-D-L-P-K-G-L-F-V-F-A-G-I-D-G-V-R-F-R-R-P-V-V-P-G-D-Q-L-V-I-H-C-E-L-L-S-L-K-R-K-R-F-G-K-V-K-A-E-A-K-V-D-G-E-L-V-C-S-G-E-L-M-F-S-L-V-D"} +{"text": "### FUNCTION Key component of the KaiABC oscillator complex, which constitutes the main circadian regulator in cyanobacteria Complex composition changes during the circadian cycle to control KaiC phosphorylation KaiA stimulates KaiC autophosphorylation, while KaiB sequesters KaiA, leading to KaiC autodephosphorylation Phospho-Ser-431 KaiC accumulation triggers binding of KaiB to form the KaiB complex that results in KaiC autodephosphorylation ### SEQUENCE -M-S-P-R-K-T-Y-I-L-K-L-Y-V-A-G-N-T-P-N-S-M-R-A-L-K-T-L-R-N-I-L-E-T-E-F-R-G-V-Y-A-L-K-V-I-D-V-L-K-N-P-Q-L-A-E-E-D-K-I-L-A-T-P-T-L-S-K-I-L-P-P-P-V-R-R-I-I-G-D-L-S-D-R-E-R-V-L-I-G-L-D-L-L-Y-D-E-L-A-D-N-A-F-S-S-G"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-A-D-T-K-T-A-T-P-A-T-D-A-E-E-A-T-A-T-P-P-A-A-A-P-S-S-E-A-Y-A-I-V-E-A-S-G-T-Q-M-W-V-Q-A-N-R-Y-Y-D-V-D-R-L-H-A-E-V-D-E-T-I-K-L-E-N-V-L-M-V-K-D-S-K-G-T-T-L-G-Q-P-F-V-K-D-A-T-V-A-L-K-V-M-A-H-R-R-G-P-K-V-I-V-Y-K-M-R-P-K-K-K-T-R-R-K-N-G-H-R-Q-E-L-T-R-V-M-V-E-S-I-T-V-G-G-K-A-I-S"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-I-S-A-G-V-D-S-S-D-L-A-K-R-G-E-S-L-I-R-Q-S-S-N-R-Y-L-T-T-V-R-I-A-F-R-A-K-Q-R-R-F-D-D-F-D-G-L-L-E-E-S-S-V-K-P-V-Q-R-A-I-V-E-L-S-D-E-Q-D-Q-P-D-L-L-P-G"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-L-T-L-R-V-L-A-P-D-Q-N-V-F-D-G-S-A-D-E-V-I-L-P-S-T-T-G-Q-L-G-I-L-P-G-H-I-S-L-L-T-A-I-D-V-G-V-L-R-V-R-A-N-G-G-W-N-S-I-A-L-M-G-G-F-A-E-V-D-A-D-E-V-T-V-L-V-N-Q-A-E-L-G-S-T-I-D-G-N-T-A-E-A-D-F-Q-K-A-T-T-V-V-D-G-L-E-G-Q-P-A-S-P-E-K-V-K-A-Q-Q-Q-L-N-M-A-R-A-R-M-Q-A-S-K-S-A-D"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-P-L-L-N-S-L-A-T-P-Y-A-E-A-L-L-Q-V-T-E-A-R-G-E-S-Q-T-V-A-D-Q-C-K-Q-L-L-E-I-W-D-S-S-A-D-F-R-N-A-M-V-S-P-V-L-E-P-D-A-K-K-M-A-L-Q-A-L-V-G-E-Q-V-T-P-S-M-L-N-L-L-K-V-L-A-D-R-Q-R-L-L-A-F-D-A-V-M-L-R-Y-L-E-L-Y-R-E-Q-Q-G-I-T-L-A-E-V-R-S-A-Q-T-L-T-E-D-Q-Q-A-A-L-S-K-K-V-Q-A-M-A-G-T-N-M-V-D-I-D-L-S-V-D-P-S-L-I-G-G-F-V-V-S-L-G-S-Q-V-I-D-A-S-L-A-G-Q-V-R-R-L-G-L-A-L-A-K-A-S"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-T-L-N-F-N-P-L-E-T-N-L-V-N-L-A-I-V-I-G-V-L-V-W-F-L-R-G-F-L-G-G-I-L-D-R-R-R-Q-A-I-L-Q-E-L-Q-D-A-E-T-R-L-K-T-A-T-E-E-L-S-K-A-Q-S-D-L-A-A-A-Q-Q-K-A-D-K-I-R-V-D-G-E-A-R-A-A-A-I-R-S-D-G-E-Q-R-T-I-A-A-M-A-A-V-K-Q-G-A-A-A-D-A-D-A-E-A-A-R-I-K-D-I-L-R-R-E-A-A-L-A-A-I-D-K-V-L-S-D-L-P-S-R-L-D-D-Q-A-Q-A-R-L-I-D-S-T-I-T-N-L-E-N-A"} +{"text": "### FUNCTION Involved in the binding and/or turnover of quinones at the Q site of Photosystem II ### SEQUENCE -M-T-P-S-L-S-N-F-L-S-S-L-V-W-G-G-L-I-V-V-V-P-A-T-I-G-L-I-L-I-S-Q-T-D-R-L-D-R-K-L"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-R-I-S-A-D-D-V-R-K-V-A-K-L-A-R-L-D-L-P-E-E-K-I-A-T-Y-T-G-Q-L-E-S-I-L-E-Y-V-G-Q-L-E-S-I-D-T-E-G-V-P-E-T-T-R-A-V-E-V-T-N-V-T-R-E-D-G-V-T-P-T-P-V-R-E-D-I-L-N-Q-A-P-Q-R-E-G-D-F-F-R-V-P-K-I-L-A-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-Q-R-T-R-L-G-D-L-L-R-P-L-N-S-E-Y-G-K-V-V-P-G-W-G-T-T-P-V-M-G-I-F-M-V-L-F-L-V-F-L-L-V-I-L-Q-L-Y-N-K-S-L-I-L-E-G-I-N-V-N-W-N-G-L-G"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-S-S-P-A-L-S-V-A-I-G-V-L-A-V-L-L-G-M-T-G-F-G-V-Y-Q-A-F-G-P-P-S-K-A-L-D-D-P-F-D-D-H-E-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-A-L-K-I-S-V-Y-S-V-V-F-F-F-I-G-I-F-V-F-G-F-L-A-S-D-P-S-R-T-P-S-R-K-D-L-E-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-S-F-T-L-D-L-L-A-Q-L-P-E-A-Y-Q-A-F-S-P-L-I-D-I-L-P-L-I-P-V-F-F-L-L-L-A-F-V-W-Q-A-S-V-G-F-R"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-Q-R-N-P-N-P-N-N-L-P-V-E-L-N-R-T-S-L-Y-L-G-L-L-F-V-F-V-T-G-V-L-M-S-S-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-G-N-K-S-P-F-P-D-G-R-I-P-D-R-L-P-D-G-R-P-A-V-P-W-R-S-R-W-T-E-G-V-L-P-L-W-L-V-A-T-A-G-G-M-A-V-L-F-V-V-G-L-F-F-Y-G-S-Y-T-G-V-G-S-A"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-V-E-S-E-D-W-L-I-V-G-K-L-V-G-A-Q-G-L-Q-G-E-L-R-V-N-P-A-S-D-F-P-E-R-F-T-T-P-G-S-R-W-L-R-G-R-K-G-G-E-P-K-E-V-Q-L-K-K-G-R-Q-L-P-G-K-S-L-F-I-L-R-L-E-G-I-D-S-R-D-A-A-E-A-L-V-G-Q-E-L-L-V-P-A-S-D-R-P-E-L-E-E-G-E-F-H-L-L-D-L-V-G-L-E-A-R-L-H-A-D-E-P-A-I-G-V-V-T-D-L-I-S-G-G-N-D-L-L-E-L-K-T-S-A-G-R-T-L-L-I-P-F-V-E-S-I-V-P-E-V-H-L-E-K-G-W-L-L-L-T-P-P-P-G-L-L-D-L"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-Q-E-A-I-L-E-K-V-R-S-I-V-A-E-Q-L-S-V-D-A-G-E-V-K-P-E-S-N-F-Q-N-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-A-F-D-I-E-I-P-D-E-A-A-E-G-I-T-T-V-G-D-A-V-K-Y-I-E-D-K-Q-A"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-G-G-A-K-K-A-A-A-A-A-A-R-A-A-A-N-R-M-L-A-D-N-R-Q-A-R-H-Q-Y-E-I-L-E-T-L-E-T-G-I-E-L-V-G-T-E-V-K-S-I-R-N-G-K-A-N-L-R-D-G-F-C-L-I-R-N-G-E-L-Q-L-H-N-V-H-I-S-P-H-S-H-A-G-A-Y-F-N-H-D-P-L-R-T-R-K-L-L-A-H-R-R-E-I-D-K-L-R-G-Q-L-D-Q-K-G-L-A-L-I-P-L-N-I-H-L-K-G-S-W-I-K-L-T-I-G-L-G-K-G-R-K-L-H-D-K-R-A-A-E-K-E-K-Q-S-K-K-E-V-K-A-A-I-A-R-F"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-A-E-Q-F-S-M-L-R-S-E-L-T-E-L-L-L-V-A-V-G-A-V-P-G-A-L-L-R-W-Q-L-A-H-H-L-G-D-Q-N-L-L-V-N-V-L-G-A-A-L-L-G-L-L-A-G-R-P-V-A-P-R-R-Q-L-L-V-G-I-G-F-C-G-S-L-T-T-F-S-S-W-M-L-A-A-M-K-H-V-S-A-G-D-W-P-A-A-L-G-L-I-G-L-T-L-G-L-G-L-G-A-A-A-L-G-F-S-L-G-R-R-L-R-P-P-E-Q-P-R-S-E-P"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-A-G-S-A-P-E-A-L-L-V-G-L-G-A-I-P-G-A-W-L-R-L-K-V-V-N-H-F-E-P-M-V-P-K-K-H-W-G-T-L-L-V-N-V-I-S-S-F-A-L-G-L-V-L-A-L-D-E-T-C-S-A-S-S-G-I-A-L-L-M-G-V-G-F-F-G-T-L-S-T-F-S-T-F-V-V-E-L-L-N-E-L-R-A-G-H-L-L-A-A-A-A-L-A-V-I-S-I-V-A-G-L-I-A-A-A-A-G-Y-G-L-G-A-Y-G"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-T-F-E-G-R-F-T-D-T-A-D-L-R-I-A-V-V-V-A-R-F-N-D-L-V-T-S-K-L-L-S-G-C-L-D-C-L-S-R-H-G-I-D-T-A-E-T-S-S-Q-L-D-V-A-W-V-P-G-S-F-E-L-P-I-V-A-Q-N-L-A-Q-S-G-R-Y-Q-V-V-I-T-L-G-A-V-I-R-G-D-T-P-H-F-D-V-V-V-A-E-A-S-K-G-I-A-T-V-A-R-E-S-G-V-P-V-I-F-G-V-L-T-T-D-T-M-Q-Q-A-L-E-R-A-G-I-K-S-N-L-G-W-S-Y-G-L-Q-A-L-E-M-G-S-L-M-A-A-L-A-Q-S"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-N-V-A-R-K-R-R-N-K-I-L-R-L-A-R-G-F-R-G-G-N-G-T-Q-F-R-T-A-N-Q-R-V-M-K-A-L-C-N-A-Y-R-D-R-R-R-R-K-R-D-F-R-R-L-W-I-A-R-I-N-A-A-A-R-I-N-G-V-S-Y-S-R-L-M-G-G-L-K-K-A-D-V-R-L-N-R-K-M-L-A-Q-L-A-V-V-D-P-G-S-F-S-N-V-V-A-T-A-K-G"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-S-N-D-F-R-T-G-T-T-I-E-I-D-G-A-V-W-R-V-V-E-F-L-H-V-K-P-G-K-G-S-A-F-V-R-S-K-L-K-A-V-K-T-G-N-V-V-E-K-T-F-R-A-G-E-M-L-P-Q-A-L-L-E-K-A-S-L-Q-H-T-Y-M-E-G-E-D-Y-V-F-M-D-M-S-T-Y-E-E-T-R-L-S-A-D-Q-I-G-E-S-R-K-Y-L-K-E-G-M-E-V-N-V-V-S-W-N-G-S-P-L-E-V-E-L-P-N-S-V-V-L-E-I-T-E-T-D-P-G-V-K-G-D-T-A-T-G-G-T-K-P-A-I-L-E-T-G-A-Q-V-M-V-P-L-F-L-S-I-G-E-K-I-K-V-D-T-R-S-D-S-Y-L-G-R-E-N-G"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-G-F-G-L-P-N-F-G-Q-L-T-E-A-F-K-K-A-Q-E-I-Q-Q-N-A-Q-A-L-Q-D-E-L-D-G-M-E-I-E-G-K-S-A-D-G-R-A-S-V-W-L-S-G-N-Q-Q-P-L-R-V-R-L-D-P-E-L-L-S-A-G-Q-E-T-C-E-A-A-T-L-E-A-L-Q-A-A-Y-E-Q-S-T-A-T-M-K-G-R-M-E-E-L-T-G-G-L-N-L-N-L-P-G-M-G-G"} +{"text": "### FUNCTION Involved in succinate export with YjjP Both proteins are required for export ### SEQUENCE -M-G-V-I-E-F-L-L-A-L-A-Q-D-M-I-L-A-A-I-P-A-V-G-F-A-M-V-F-N-V-P-V-R-A-L-R-W-C-A-L-L-G-S-I-G-H-G-S-R-M-I-L-M-T-S-G-L-N-I-E-W-S-T-F-M-A-S-M-L-V-G-T-I-G-I-Q-W-S-R-W-Y-L-A-H-P-K-V-F-T-V-A-A-V-I-P-M-F-P-G-I-S-A-Y-T-A-M-I-S-S-V-K-I-S-Q-L-G-Y-S-E-P-L-M-I-T-L-L-T-N-F-L-T-A-S-S-I-V-G-A-L-S-I-G-L-S-I-P-G-L-W-L-Y-R-K-R-P-R-V"} +{"text": "### FUNCTION Toxic component of a type I toxin-antitoxin When overexpressed kills cells within minutes ### SEQUENCE -M-K-Q-Q-K-A-M-L-I-A-L-I-V-I-C-L-T-V-I-V-T-A-L-V-T-R-K-D-L-C-E-V-R-I-R-T-G-Q-T-E-V-A-V-F-T-A-Y-E-P-E-E"} +{"text": "### FUNCTION Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions ### SEQUENCE -M-H-A-T-T-V-K-N-K-I-T-Q-R-D-N-Y-K-E-I-M-S-V-I-V-V-V-L-L-L-T-L-T-L-I-A-I-F-S-A-I-D-Q-L-S-I-S-E-M-G-R-I-A-R-D-L-T-H-F-I-I-N-S-L-Q-D-W-K"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-N-I-T-A-T-V-L-L-A-F-G-M-S-M-D-A-F-A-A-S-I-G-K-G-A-P-L-H-K-P-K-F-S-E-A-L-R-T-G-L-I-F-G-A-V-E-T-L-T-P-L-I-G-W-G-M-G-M-L-A-S-R-F-V-L-E-W-N-H-W-I-A-F-V-L-L-I-F-L-G-G-R-M-I-I-E-G-F-R-G-A-D-D-E-D-E-E-P-R-R-R-H-G-F-W-L-L-V-T-T-A-I-A-T-S-L-D-A-M-A-V-G-V-G-L-A-F-L-Q-V-N-I-I-A-T-A-L-A-I-G-C-A-T-L-I-M-S-T-L-G-M-M-V-G-R-F-I-G-S-I-I-G-K-K-A-E-I-L-G-G-L-V-L-I-G-I-G-V-Q-I-L-W-T-H-F-H-G"} +{"text": "### FUNCTION Toxic component of a type I toxin-antitoxin When overexpressed kills cells within minutes ### SEQUENCE -M-L-T-K-Y-A-L-V-A-V-I-V-L-C-L-T-V-L-G-F-T-L-L-V-G-D-S-L-C-E-F-T-V-K-E-R-N-I-E-F-K-A-V-L-A-Y-E-P-K-K"} +{"text": "### FUNCTION Toxic component of a type I toxin-antitoxin When overexpressed kills cells within minutes ### SEQUENCE -M-L-T-K-Y-A-L-V-A-V-I-V-L-C-L-T-V-L-G-F-T-L-L-A-G-D-S-L-C-E-F-T-V-K-E-R-N-I-E-F-R-A-V-L-A-Y-E-P-K-K"} +{"text": "### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate May function as an ADP-ribosylase ### SEQUENCE -M-K-A-D-K-Q-L-V-S-T-S-K-F-L-S-L-V-L-R-H-Q-P-G-V-I-G-M-T-L-D-E-Q-G-W-L-E-I-D-G-L-I-A-N-A-N-T-R-G-K-K-L-T-L-E-L-I-H-E-V-V-A-T-N-D-K-K-R-F-V-L-S-D-D-G-L-R-I-R-A-S-Q-G-H-S-V-A-G-V-D-L-N-L-T-E-A-N-P-P-A-T-L-Y-H-G-T-V-D-A-F-L-P-R-I-R-E-Q-G-L-Q-K-R-S-R-N-H-V-H-L-S-A-D-E-A-T-A-T-N-V-G-S-R-R-G-K-P-K-L-L-L-I-A-A-Q-R-M-H-Q-D-G-H-I-F-Y-L-S-E-N-E-V-W-L-V-D-S-V-P-P-T-Y-L-T-F-P-T"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-G-K-K-E-E-A-F-E-V-E-G-T-V-T-Q-A-L-A-N-T-R-F-R-V-Q-L-E-T-G-N-E-V-M-A-H-V-A-G-R-M-R-K-H-F-I-R-I-V-P-G-D-K-V-R-V-E-L-S-P-Y-D-L-T-K-G-R-I-V-Y-R-E-R"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-F-V-D-G-G-R-Q-Y-R-V-E-P-G-M-E-L-D-V-D-Y-R-D-I-A-A-G-E-N-L-K-F-E-T-V-L-A-V-G-A-E-D-G-L-K-L-G-A-P-T-L-D-G-V-S-V-S-A-S-V-L-G-M-S-Q-D-K-K-I-Y-I-Q-K-F-R-R-R-K-H-S-K-K-R-T-G-H-R-Q-K-N-T-R-I-R-I-E-E-I-A-G-V"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-T-R-S-R-A-R-K-R-S-R-V-R-S-R-T-R-R-K-D-P-I-F-V-D-G-H-R-P-R-P-M-Y-V-D-Y-K-D-L-E-L-L-S-K-M-V-N-R-Q-G-R-I-M-G-R-R-K-S-G-C-T-A-A-S-Q-H-A-V-T-A-A-I-K-R-A-R-F-M-A-L-L-P-Y-V-G-E"} +{"text": "### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-V-L-S-R-K-K-N-E-S-I-V-I-N-N-D-I-K-I-V-V-V-E-I-R-G-D-K-V-R-L-G-V-E-A-P-R-E-V-P-V-H-R-R-E-V-Y-D-A-I-Q-R-N-N-E-A-F-D-A-N-A-P-A-D-S-N-D-V-S"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-T-T-T-T-T-A-E-D-G-F-P-A-T-G-R-L-A-S-V-D-Y-G-T-V-R-I-G-V-A-I-C-D-P-D-W-I-L-A-S-P-L-E-V-H-P-V-S-T-P-E-K-D-A-Q-Y-F-I-D-L-A-K-S-E-R-I-A-A-W-V-V-G-L-P-I-H-C-D-G-G-E-S-D-K-S-K-E-S-R-K-F-A-A-W-L-K-E-T-T-G-L-P-T-R-L-F-D-E-R-F-T-T-V-A-A-N-A-K-I-R-Q-G-K-T-T-R-K-K-T-K-Q-R-V-D-A-V-A-A-Q-V-L-L-E-S-F-L-E-A-C-R-Y-R-G-E-L-A-G-H-C-L-E-D-S-T-S-D-E-S-L-D-D-A"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-F-C-H-S-D-N-D-K-V-Q-D-S-R-T-A-E-A-G-Y-V-V-R-R-K-R-L-C-Q-T-C-Q-R-R-F-T-T-L-E-Q-I-D-A-L-N-V-R-V-V-K-S-D-E-T-R-E-P-F-D-R-E-K-I-K-R-G-I-E-R-A-C-S-K-R-A-V-T-S-D-E-I-E-K-T-V-Q-K-I-E-E-A-I-Y-A-E-F-D-M-E-I-P-T-A-T-I-G-E-V-V-L-R-K-L-A-T-L-D-E-V-A-Y-I-R-F-A-S-V-Y-R-D-F-D-D-A-K-D-F-L-Q-I-V-S-N-L-Q-R-D-A-E-T-E-G-R"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-P-S-I-D-G-T-T-G-N-L-P-S-G-R-V-A-I-I-A-S-R-Y-N-A-N-I-C-D-S-M-V-Q-A-A-L-Q-S-L-S-D-A-G-I-P-E-D-K-Q-W-L-I-R-V-P-G-A-W-E-L-C-W-A-V-E-Q-A-F-Q-H-A-D-V-I-G-A-I-T-L-G-C-V-I-K-G-E-T-T-H-D-E-H-I-N-R-A-V-S-D-T-L-M-E-Q-A-V-R-S-G-R-P-V-G-F-G-L-L-T-C-N-T-V-E-Q-A-I-Q-R-S-G-G-A-V-G-N-K-G-H-E-A-A-D-A-M-L-E-M-L-R-L-Q-T-K-M-R"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-T-E-A-G-A-K-K-A-A-G-K-K-S-G-K-G-K-G-K-N-A-K-K-N-Q-P-N-I-T-P-V-A-E-N-R-K-A-K-F-R-Y-E-I-L-D-S-V-E-C-G-M-M-L-M-G-S-E-V-K-S-M-R-E-G-K-L-S-L-D-E-A-H-I-R-V-T-N-G-E-L-W-L-V-G-S-D-I-A-H-Y-N-N-A-G-M-W-N-H-D-P-R-R-P-R-K-L-L-V-H-A-K-E-F-D-K-F-A-G-R-A-F-E-R-G-L-T-L-I-P-L-R-V-Y-F-S-E-R-G-L-A-K-C-V-M-G-L-V-K-G-K-K-L-H-D-K-R-E-T-I-K-K-R-E-S-D-R-G-L-Q-R-A-M-R-R-K"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-T-F-V-S-D-L-F-A-I-A-L-G-G-S-I-G-A-V-L-R-Y-L-I-T-L-T-V-V-S-A-P-L-S-G-W-L-T-L-H-G-S-V-G-T-T-L-A-N-L-L-G-C-C-A-L-G-G-L-F-Q-F-S-Q-A-L-V-A-S-D-W-V-A-T-G-W-A-A-S-L-A-H-P-R-T-L-L-A-V-R-I-G-V-L-G-S-L-T-T-F-S-T-L-I-G-E-T-A-V-F-A-S-Q-G-R-I-L-A-S-S-M-L-L-G-I-N-V-I-A-G-W-C-L-F-W-A-A-A-A-V-V-R-N-W-T-S"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-N-A-I-M-D-M-V-D-K-A-N-Q-K-E-N-A-P-Q-F-D-I-G-D-T-V-D-V-H-S-K-I-L-E-G-N-K-E-R-I-Q-V-F-T-G-V-V-I-G-R-S-G-K-G-A-Q-E-M-F-T-V-R-R-I-V-A-G-E-G-V-E-R-K-F-P-V-H-S-P-R-I-E-K-V-E-V-K-R-S-G-V-T-R-R-A-K-L-Y-F-L-R-D-R-V-G-K-A-V-R-L-K-E-R-R-R-V"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-Q-N-F-T-V-H-Q-G-V-V-A-T-L-D-R-A-N-V-D-T-D-Q-I-I-P-K-Q-F-L-K-R-I-E-R-T-G-F-G-Q-F-L-F-F-D-W-R-F-L-E-D-G-E-T-E-N-P-D-F-E-L-N-R-I-N-V-K-G-A-S-I-L-L-T-R-Q-N-F-G-S-G-S-S-R-E-H-A-V-W-A-L-D-D-Y-G-F-R-A-V-I-A-P-S-F-A-D-I-F-F-N-N-C-F-K-N-G-V-L-P-I-A-L-S-E-E-D-V-E-E-L-F-Q-R-A-E-K-G-N-P-Y-Q-L-T-V-D-L-E-N-Q-V-I-T-D-G-Q-G-F-E-R-S-F-E-V-D-A-S-R-R-H-N-M-L-H-G-L-D-D-I-A-Q-T-L-L-H-E-D-K-I-T-A-F-E-E-A-R-G"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-T-N-K-K-K-R-I-R-R-N-V-S-N-G-V-A-H-V-H-A-T-F-N-N-T-T-V-T-I-T-D-A-K-G-D-T-L-C-W-A-S-A-G-T-S-G-F-K-G-S-R-K-S-T-P-F-A-G-Q-C-A-A-Q-Q-A-A-E-K-A-T-K-F-G-M-R-D-V-E-V-R-V-K-G-P-G-S-G-R-E-S-A-I-T-A-L-Q-A-A-G-L-N-V-K-L-I-E-E-V-T-P-I-P-H-N-G-C-R-P-R-K-K-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-P-R-L-M-G-V-D-I-P-N-D-K-Q-I-Q-Y-S-L-T-Y-L-Y-G-L-G-L-Y-R-A-R-E-V-C-E-K-L-G-I-D-P-T-S-P-A-S-D-I-S-D-E-D-V-G-R-I-A-A-L-L-E-R-D-Y-L-V-E-G-P-L-R-R-Q-V-T-Q-N-I-S-R-M-R-E-I-K-S-Y-R-G-I-R-H-R-V-S-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-T-V-A-G-K-K-G-V-K-D-L-R"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-A-L-A-R-R-N-V-Q-P-E-N-R-D-S-T-R-I-N-A-Q-I-R-I-T-P-V-R-V-V-S-E-E-G-E-Q-L-G-I-I-P-T-E-Q-A-L-E-R-A-R-D-A-G-L-D-L-V-E-V-A-P-G-E-R-P-P-V-C-R-I-M-D-Y-G-K-F-K-Y-D-K-N-K-K-K-N-S-G-S-S-H-T-K-T-K-E-I-R-L-R-P-K-T-G-D-E-D-I-R-T-K-V-R-Q-A-E-K-F-L-E-H-K-D-K-V-Q-V-S-V-L-F-R-G-R-E-M-A-H-I-E-E-G-R-K-V-M-E-Q-V-I-E-I-L-S-E-V-G-K-V-E-T-K-P-Q-Q-H-G-R-R-M-I-C-M-I-A-P-K"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-P-F-D-S-E-I-V-E-V-K-T-R-P-G-E-E-V-A-T-L-A-G-G-C-F-W-C-T-E-A-V-F-E-R-M-E-G-V-N-D-V-V-S-G-Y-I-G-G-K-I-K-N-P-N-Y-K-Q-V-C-G-K-M-T-G-H-A-E-A-V-Q-I-Y-Y-D-P-S-K-T-N-F-E-E-L-L-K-V-F-F-K-T-H-D-P-T-T-L-N-R-Q-G-A-D-G-G-P-Q-Y-R-S-S-I-F-V-H-N-D-E-Q-R-E-I-A-K-K-T-M-E-K-L-G-E-E-Y-R-D-P-I-V-T-L-I-E-P-A-T-K-F-Y-V-A-E-E-Y-H-Q-D-Y-Y-R-R-N-P-N-A-G-Y-C-Q-A-V-V-A-A-K-V-R-K-F-N-R-N-F-G-D-K-I-K-G-S-G-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-V-V-G-L-G-N-P-G-R-K-Y-D-Q-T-R-H-N-I-G-F-M-V-A-D-A-L-V-R-R-Y-V-G-S-P-P-T-T-K-F-E-G-E-I-S-E-C-R-I-E-N-E-K-V-L-V-L-C-P-Q-T-Y-M-N-A-S-G-Q-S-V-R-K-A-M-D-F-Y-K-L-S-P-E-D-I-L-V-I-C-D-D-L-N-L-E-T-G-R-V-R-L-R-R-S-G-S-A-G-G-Q-K-G-L-V-D-I-I-R-H-L-G-S-E-Q-W-A-R-L-K-I-G-I-G-R-P-P-A-K-W-Q-V-S-D-Y-V-L-G-K-F-D-K-T-E-L-E-E-M-E-H-A-I-V-H-S-C-D-A-T-A-C-W-V-A-D-G-V-T-E-A-M-N-R-Y-N-A-A-S-G-T"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-K-V-N-T-Y-E-T-L-F-I-L-D-S-N-H-Y-A-R-D-P-G-G-V-A-K-Q-L-E-E-L-I-A-E-N-G-G-E-V-Q-V-S-R-M-W-M-E-Q-K-L-A-Y-P-I-D-K-H-Q-K-G-T-Y-Y-L-I-Y-F-S-M-E-G-P-N-L-T-Q-L-A-R-A-F-A-L-A-E-P-V-I-R-E-L-T-I-K-L-D-P-R-L-V-E-P-I-L-A-N-A-R-G-E-H-F-T-G-P-A-G-A-E-G-S-D-D-E-S-T-E-S-T-D-E-A-V-A-E-T-A-D-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-S-K-S-A-T-S-H-F-K-R-L-P-K-G-Q-N-G-G-I-E-L-L-L-I-H-N-V-E-H-L-G-R-Q-G-D-L-V-E-V-K-A-G-Y-A-L-N-Y-L-L-P-Q-G-L-A-T-I-A-T-D-H-H-K-R-M-V-E-K-H-R-E-K-L-R-A-I-E-L-E-K-L-K-S-Y-R-E-Q-A-D-E-L-A-K-Q-S-I-T-I-E-A-N-A-N-D-E-G-H-L-Y-G-S-V-G-P-H-E-I-V-D-A-L-K-A-S-G-I-T-L-A-Q-D-Q-I-R-L-E-G-P-L-K-E-L-G-L-Y-T-V-K-I-H-L-H-S-E-V-D-A-S-L-K-V-W-V-V-P-T-V-A-A-E-G-G-E-P-G-A-S"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-Q-D-G-I-H-P-N-Y-Q-E-T-S-V-T-C-G-C-G-N-T-F-T-T-R-S-T-R-P-E-L-K-I-D-I-C-S-E-C-H-P-F-Y-T-G-K-L-K-Y-V-D-T-A-G-R-I-D-K-F-Q-K-K-F-A-A-G-T-Y-G-S-L-Q-K-K-K-A-K-K-A-T-K"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-E-Q-P-N-E-E-L-Q-S-E-D-E-Q-F-D-P-Q-E-T-V-S-F-E-G-E-T-A-A-N-D-E-A-F-A-E-A-G-E-E-T-R-D-E-E-M-T-R-L-R-G-E-V-E-E-A-S-K-R-V-L-Q-A-Q-A-E-A-E-N-F-R-K-R-L-R-R-D-T-E-A-Q-L-K-F-A-G-M-P-L-V-T-D-I-L-Q-V-R-D-N-L-L-R-A-I-E-A-A-T-T-A-G-D-G-E-S-A-A-G-L-V-E-G-V-S-M-V-R-K-Q-L-D-D-V-L-A-K-H-A-I-K-E-I-P-A-E-G-E-L-F-D-P-N-F-H-E-A-I-S-Q-M-P-H-P-E-I-A-S-G-M-V-A-H-V-A-T-P-G-F-Q-M-H-D-R-V-V-R-P-A-Q-V-V-V-S-T-G-D-G-S-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-Q-V-T-G-Q-A-K-F-Q-V-P-G-G-Q-A-T-P-A-P-P-V-G-T-S-L-G-K-Y-G-V-N-L-G-Q-F-V-Q-Q-F-N-D-R-T-K-E-Y-N-G-T-P-I-P-V-I-V-T-V-Y-N-D-R-S-F-D-F-I-T-K-S-P-P-A-A-S-M-L-M-Q-S-A-G-I-A-K-G-S-G-V-P-N-K-D-K-V-A-T-V-T-R-A-Q-C-E-E-I-A-Q-K-K-M-E-D-L-N-A-R-D-I-D-Q-A-T-R-M-I-E-G-T-A-R-S-M-G-I-I-V-D-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-L-N-D-V-H-R-G-I-T-K-H-R-P-R-K-R-I-G-R-G-P-G-S-G-T-G-K-T-S-G-R-G-H-K-G-H-K-S-R-S-G-Y-S-R-K-P-N-F-Q-G-G-A-M-P-M-F-R-R-V-P-K-R-G-F-N-N-R-W-A-L-T-I-F-A-V-N-V-G-K-L-N-D-A-F-N-E-G-E-T-V-T-L-E-A-L-A-A-K-N-L-A-K-G-N-F-D-E-L-K-V-L-G-D-G-E-L-T-K-K-L-T-I-Q-A-H-R-F-S-K-S-A-E-E-K-I-S-A-A-G-G-T-A-E-K-L-A-P-K-R-T-P-D-E-R-V-E-A-L-K-S-E-K"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-N-A-R-N-K-R-N-N-K-N-E-E-Q-G-L-E-A-G-L-L-D-R-V-V-K-I-K-R-C-A-A-V-V-K-G-G-R-R-F-S-F-A-A-M-V-V-V-G-N-G-S-G-Q-V-G-W-G-Y-G-K-A-N-E-V-P-P-S-V-Q-K-A-Q-K-Q-A-S-R-S-M-I-H-V-P-L-V-E-G-S-I-P-H-Q-V-W-G-R-Y-G-A-A-R-V-V-L-I-P-A-G-A-G-T-G-I-I-A-G-Q-A-V-R-A-V-C-E-A-C-G-I-H-D-I-L-T-K-S-Y-G-T-N-N-P-V-T-L-V-K-A-T-L-D-A-M-S-K-L-R-T-R-E-Q-I-A-A-L-R-G-L-N-P-D-D-L-I-E-A"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-N-K-K-L-Q-S-K-R-L-R-R-R-R-H-V-R-N-K-L-R-G-S-A-D-Q-P-R-L-C-I-Q-R-T-L-K-H-F-A-C-Q-V-V-D-D-Q-A-G-K-T-L-L-S-A-S-T-R-D-K-T-V-R-D-Q-V-K-A-G-G-N-C-D-A-A-A-L-V-G-K-L-V-A-E-K-A-A-E-A-G-V-K-T-V-K-L-D-R-G-H-N-K-Y-H-G-R-V-K-A-F-A-D-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-P-V-A-I-P-S-G-V-T-V-S-I-A-D-R-N-I-D-V-E-G-P-K-G-K-L-S-F-K-H-R-P-E-V-K-V-A-V-D-S-D-T-N-Q-V-I-V-S-R-D-G-D-D-R-P-S-R-E-F-H-G-L-T-R-A-I-V-A-N-M-L-V-G-V-K-D-G-Y-E-K-K-L-E-I-V-G-V-G-Y-L-A-S-I-S-G-D-T-L-Q-L-R-V-G-Y-A-N-E-L-H-R-K-I-P-T-D-L-T-V-T-C-P-D-Q-T-H-V-V-I-Q-G-C-D-K-Q-S-V-G-Q-F-A-A-E-I-R-S-L-R-K-P-E-P-Y-K-G-K-G-I-R-Y-Q-G-E-Q-V-K-I-K-P-G-K-S-A-T-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-M-T-D-P-I-A-D-M-L-T-R-I-R-N-A-V-R-V-E-R-P-F-V-D-I-P-A-S-R-V-K-R-G-L-A-D-V-L-K-R-E-G-F-I-W-D-W-K-E-E-K-L-E-E-E-P-V-G-Y-L-R-L-E-L-K-Y-G-P-N-G-E-R-V-I-Q-S-I-R-R-I-S-K-P-G-R-R-L-Y-S-R-S-K-E-L-K-P-V-L-G-G-L-G-I-R-I-I-S-T-S-K-G-V-I-S-D-R-E-A-R-R-D-K-I-G-G-E-V-L-C-E-V-S"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-S-K-S-K-V-A-K-A-L-R-T-P-K-F-S-T-R-K-E-N-R-C-K-F-C-G-R-P-R-S-V-Y-R-K-F-G-L-C-R-I-C-F-R-E-N-A-N-A-G-L-I-P-G-V-R-K-S-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-P-N-M-S-S-N-I-P-R-M-Q-Q-R-Y-D-E-S-V-R-A-A-L-T-E-T-Y-G-Y-K-N-V-H-Q-V-P-R-L-L-K-I-S-M-N-M-G-V-G-A-A-V-G-D-K-K-V-L-D-L-A-I-D-S-M-T-Q-I-T-G-Q-K-P-V-T-T-I-A-R-K-S-I-A-G-F-R-L-R-E-G-M-P-I-G-C-M-V-T-M-R-R-Q-R-M-Y-E-F-L-D-R-L-V-S-I-V-L-P-R-V-R-D-F-R-G-I-S-R-K-A-F-D-G-N-G-N-Y-T-L-G-L-N-E-Q-L-V-F-P-E-L-N-P-D-K-F-V-R-P-Q-G-M-N-I-S-F-V-T-S-A-K-T-D-D-E-A-R-E-M-L-R-L-F-G-M-P-F-K-Q-P-K-E-K-E-Q-A-G-A-A"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-F-R-V-D-D-E-V-I-V-I-A-G-A-D-K-G-H-R-G-K-I-L-K-V-D-R-D-K-D-K-V-V-V-E-G-A-A-R-V-W-K-H-V-R-Q-S-Q-K-N-P-Q-G-G-R-L-N-K-E-M-P-M-S-A-S-N-V-M-L-V-D-P-S-T-G-K-P-T-R-I-G-V-R-Y-L-E-D-G-S-K-E-R-F-A-K-A-S-G-E-S-L-G-Q-I-A-P-A-K-A-S-K-A-A-S"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-D-V-A-D-N-T-G-A-R-E-V-M-C-I-K-V-L-G-G-S-R-R-R-F-A-T-V-G-D-V-I-V-C-S-V-K-S-V-I-P-G-S-E-V-K-K-K-A-V-V-R-A-V-I-V-R-V-K-Q-P-T-R-R-P-D-G-S-Y-I-R-F-D-S-N-A-V-V-L-V-D-K-D-R-N-P-R-G-T-R-I-F-G-A-V-A-R-E-L-R-E-N-N-F-M-K-I-V-S-L-A-N-E-V-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-V-V-A-G-I-V-T-S-D-K-M-S-K-T-R-R-V-E-I-A-R-L-V-K-H-P-K-Y-K-K-Y-I-R-R-R-T-V-C-H-V-H-D-E-N-N-E-S-G-V-G-D-K-V-E-I-I-E-S-E-P-L-S-K-L-K-R-W-R-L-V-R-V-L-E-K-S-T-A-V-D-V-V-A-L-R-A-A-R-K-N-A-E-A-E-G-L-A-A-A-H-A-G-E-P-E-T-E-S-A-A-T-D-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-A-L-M-P-K-R-V-K-H-R-K-S-Q-R-G-R-I-K-G-N-A-T-R-G-N-T-V-V-F-G-D-Y-G-I-Q-S-L-D-A-G-W-I-K-A-T-T-I-E-A-G-R-I-A-A-Q-Q-Y-V-R-G-Q-G-K-L-Y-I-R-I-F-P-D-K-S-V-T-S-T-P-L-E-T-R-M-G-K-G-K-G-E-P-D-F-W-A-A-V-V-K-P-G-T-I-L-Y-E-L-S-G-V-T-E-Q-Q-A-K-V-C-F-A-R-L-A-S-K-M-P-V-K-V-R-F-V-E-R-R-S-A"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-Q-F-N-A-Y-H-K-N-A-R-I-S-A-Q-K-V-R-L-V-A-D-L-V-R-G-M-F-A-D-E-A-L-D-T-L-K-Y-Q-P-Q-R-G-A-R-M-L-E-K-V-I-K-S-A-V-G-N-A-Q-D-P-D-Q-N-S-G-R-S-H-R-I-E-E-L-V-I-T-D-V-R-V-D-G-G-P-M-F-K-R-I-Q-P-R-A-R-G-M-A-F-M-I-K-K-R-S-S-H-I-R-V-G-L-T-H-I-E-N-V"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-S-K-K-G-P-F-V-D-P-K-V-F-F-K-V-Q-K-A-A-E-T-G-S-K-E-P-I-K-T-W-A-R-S-C-T-I-V-P-E-F-V-N-V-T-F-M-V-H-N-G-R-Q-H-I-K-V-L-V-T-E-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-K-G-H-G-G-K-G-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-A-I-Q-P-P-K-P-V-E-R-K-I-E-L-E-P-H-Q-I-L-L-K-P-L-V-T-E-K-G-V-H-R-A-T-R-N-N-Q-Y-A-F-Q-I-H-R-D-A-T-K-L-D-V-K-K-A-V-E-H-L-F-D-V-K-V-L-K-V-R-T-Q-T-R-K-G-K-A-R-R-F-K-Y-K-I-G-R-T-S-D-W-K-K-A-I-V-S-L-H-E-D-H-R-I-D-F-F"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-T-G-P-S-E-V-I-R-I-R-M-E-A-Y-D-H-A-V-L-D-Q-S-A-R-D-I-V-D-T-V-K-A-T-A-S-I-V-H-G-P-I-P-L-P-T-R-I-E-R-Y-T-V-L-S-S-P-F-V-N-K-K-A-R-Q-Q-Y-E-I-R-T-H-K-R-L-V-D-I-V-Q-A-S-A-K-T-I-E-A-L-N-K-L-S-L-P-A-G-V-D-I-K-I-K-A-S-A-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-G-R-I-T-S-S-R-S-Q-L-I-G-D-P-R-H-H-S-L-L-A-S-K-F-I-N-C-L-M-L-D-G-K-K-T-T-A-Q-R-V-F-Y-D-A-L-E-E-I-G-K-R-H-E-G-E-E-T-P-I-E-V-F-E-A-A-L-E-N-I-K-P-Y-I-E-V-R-S-K-R-V-G-G-A-S-Y-Q-V-P-M-Q-V-N-K-A-R-Q-Q-S-L-A-I-R-W-I-L-A-A-V-R-D-K-K-G-R-P-M-A-L-K-L-A-D-E-L-L-A-G-F-K-K-E-G-A-A-Y-T-K-R-E-N-T-H-R-M-A-D-A-N-K-A-F-A-H-F-A-W"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-R-D-P-S-T-L-R-Y-A-E-T-H-E-W-V-D-V-Q-E-E-G-G-D-K-F-A-T-I-G-I-S-A-F-A-V-E-Q-L-N-D-L-V-Y-M-D-L-P-E-V-G-R-T-L-E-V-G-E-E-F-G-E-V-E-S-V-K-A-V-S-P-L-Y-S-P-V-A-G-E-V-V-A-V-H-T-D-L-P-D-N-L-D-N-L-N-D-D-A-F-D-F-G-W-I-L-K-V-K-L-S-A-D-L-P-E-T-L-M-D-F-A-A-Y-Q-K-Q-C-S-E-A-G"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-S-R-T-G-G-K-R-P-L-E-F-P-K-S-S-R-V-V-R-S-S-E-F-T-K-A-L-R-R-G-G-V-A-A-N-D-C-L-V-V-F-A-L-P-H-D-V-P-D-A-D-G-E-P-S-P-D-E-S-K-T-V-K-C-R-L-G-V-T-I-P-K-K-T-G-N-A-V-V-R-N-R-W-K-R-L-I-R-E-A-F-R-L-N-Q-T-Q-L-P-S-G-F-D-Y-V-V-R-P-K-K-D-V-T-A-D-W-K-M-I-E-K-G-F-V-K-L-V-G-R-A-V-R-R-S-Q-S-S-A-D-R-S-S-T-R-S"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-R-T-T-K-G-A-A-R-R-Q-S-K-K-R-L-F-K-R-A-K-G-F-R-G-G-R-G-N-L-T-R-T-V-K-E-T-L-L-R-S-G-A-F-A-F-R-D-R-R-V-R-K-R-E-F-R-K-L-W-I-I-R-I-N-A-A-V-K-Q-H-G-L-R-Y-S-E-F-I-H-G-L-N-K-A-G-I-Q-L-D-R-K-S-L-S-E-M-A-I-H-D-A-A-G-F-K-Q-V-C-D-K-V-K-E-T-L-A-A"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-L-E-E-L-K-E-E-E-I-V-N-K-I-G-G-R-F-K-L-S-T-L-I-Q-K-R-L-V-Q-L-N-Q-G-S-R-A-L-V-S-V-D-T-H-D-K-M-S-I-V-L-Q-E-I-V-Q-D-K-I-F-L-N-M-E-N-E-I-E-T-V-D-D-L-D-A-I-V-A-A-S-E-A-P-E-L-D-P-S-D-L"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-N-T-S-S-A-S-K-R-L-R-Q-N-E-K-R-R-L-L-N-R-A-T-R-S-N-M-R-S-T-I-R-R-V-R-E-A-V-E-N-N-D-L-E-T-A-K-N-E-F-K-V-A-Q-K-K-L-D-R-A-A-A-N-N-L-I-H-K-N-A-A-A-R-T-K-S-R-L-N-N-L-I-K-N-A-A-Q-T-A"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-G-H-A-G-A-V-S-D-L-V-D-Q-L-S-K-L-P-G-I-G-R-K-S-A-E-R-L-A-F-H-L-L-R-V-H-E-D-E-A-L-A-L-A-S-A-I-R-R-V-R-T-D-V-R-Y-C-S-V-C-Y-N-L-S-E-T-E-L-C-R-I-C-S-D-P-K-R-D-A-T-R-L-C-V-V-E-Q-P-R-D-L-L-S-L-D-A-S-G-V-Y-S-G-L-Y-H-V-L-L-G-R-I-A-P-L-D-G-I-T-P-D-Q-L-T-I-D-S-L-V-E-R-V-R-T-G-N-F-S-E-I-I-M-A-T-N-P-T-V-E-G-D-G-T-S-L-Y-L-S-N-L-M-Q-E-F-P-V-E-I-T-R-L-A-R-G-I-T-S-G-S-V-L-E-Y-A-N-R-E-I-I-A-D-A-L-T-G-R-Q-R-L"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-V-A-V-G-T-E-I-V-Q-C-A-R-I-A-Q-M-I-Q-Q-H-G-E-Q-F-L-E-R-V-F-T-A-A-E-I-D-H-C-A-Q-R-P-D-A-T-G-H-F-S-R-R-W-A-A-K-Q-A-V-F-K-A-L-R-C-H-R-R-G-V-S-W-T-D-I-E-I-A-T-H-P-S-E-G-P-T-I-E-L-H-G-I-A-A-D-L-A-E-E-A-E-I-D-A-I-H-L-S-L-G-G-C-R-T-Q-A-I-A-Y-V-V-L-C-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-T-I-S-K-E-R-K-E-E-V-I-S-E-H-G-A-A-A-G-D-T-G-S-P-E-V-Q-I-A-I-L-T-E-R-I-N-G-L-T-E-H-M-R-T-H-R-K-D-Y-A-S-R-R-G-L-L-G-L-V-S-R-R-R-R-L-L-D-Y-V-R-G-Q-D-P-Q-R-Y-L-D-I-I-G-K-L-G-I-R-K"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-R-I-D-S-H-R-F-G-T-L-E-L-N-A-D-Q-L-F-L-F-P-Q-G-L-I-G-M-E-S-L-H-Q-W-A-L-I-P-D-P-D-N-A-S-V-A-W-L-Q-S-A-A-R-G-D-R-A-L-A-V-I-S-P-R-A-F-F-P-D-Y-R-V-H-I-G-R-R-D-L-S-S-L-H-L-T-S-G-S-E-V-Y-V-M-T-T-V-A-G-H-V-G-K-L-T-T-N-L-R-A-P-L-M-L-N-L-D-R-R-L-G-C-Q-V-I-T-N-D-D-R-P-M-R-Q-P-L-P-T-V-A-A-E-S-A-K-P-L-P-T-S-Q-V-R-A-A"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-S-R-R-L-L-K-A-A-E-A-I-R-E-V-V-A-N-A-I-V-T-E-V-R-D-P-R-V-R-D-V-T-V-I-G-V-E-V-S-P-D-M-R-E-A-K-V-K-V-S-V-M-G-D-E-T-Q-K-N-L-S-L-R-G-L-Q-N-S-A-G-F-L-Q-S-K-I-A-N-R-M-D-T-R-Y-T-P-K-L-R-F-E-V-D-R-G-Q-E-N-A-M-T-V-S-E-I-L-A-R-I-Q-Q-E-K-E-G-A-T-D-D-R-D-Q-N-D-S-G-E-D-A-T-P-H-S-N-D"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-I-A-R-M-S-T-R-R-R-A-R-E-I-V-L-Q-L-L-Y-E-A-D-L-N-D-W-R-D-A-A-T-S-R-K-F-I-R-S-R-L-Q-G-R-K-V-L-T-D-F-A-A-E-L-L-D-G-T-M-A-R-R-D-D-I-D-A-K-L-T-K-L-S-T-N-W-A-L-H-R-M-P-V-T-D-R-N-V-L-R-L-G-A-Y-E-I-L-Y-S-G-T-P-G-Q-V-A-I-S-E-A-L-T-L-A-K-R-Y-G-G-E-N-S-P-R-F-I-N-G-V-L-D-R-L-F-K-Y-H-S-N-P-E-S-V-S-S"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-M-E-Q-P-S-T-N-L-T-A-D-V-L-I-D-E-E-A-E-P-D-L-S-I-W-F-G-C-L-E-T-A-R-T-E-L-A-Q-A-A-I-A-A-A-A-V-E-G-C-D-R-G-S-V-G-V-R-I-C-D-D-A-T-I-H-P-I-N-R-E-F-L-Q-H-D-Y-P-T-D-V-I-S-F-P-Y-E-L-E-P-P-M-V-E-G-E-L-V-A-S-F-E-T-A-I-E-N-A-S-E-P-S-N-P-L-S-P-R-E-E-L-L-L-Y-V-V-H-G-T-L-H-I-V-G-H-D-D-Q-S-P-E-P-R-A-A-M-R-R-A-E-I-A-A-M-K-L-I-G-I-E-L-P-L-S-N-D-E-D-S-A-P-E-Q-D-D-S-F-D-D-D-A-S-D-S-S-G-G-I-M-S-G-G-V-S"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-T-S-D-E-I-L-M-D-A-E-E-R-M-D-K-A-V-S-V-L-Q-N-N-L-S-G-I-R-T-G-R-A-N-P-G-L-V-D-S-I-K-V-E-V-Y-G-S-L-T-P-L-K-Q-L-A-S-I-G-T-P-E-P-Q-Q-I-L-I-R-P-Y-D-A-T-T-I-K-D-I-E-K-A-I-V-A-G-D-L-G-L-N-P-Q-N-D-G-R-V-I-R-L-N-V-P-P-L-S-G-E-V-R-K-K-M-V-S-R-I-K-E-L-A-E-E-A-K-V-S-I-R-N-I-R-R-D-A-N-K-A-A-E-T-A-E-K-D-K-E-M-T-E-D-D-R-D-K-T-K-D-Q-V-Q-E-L-T-K-K-A-E-T-N-V-N-E-S-A-K-A-R-E-A-E-V-M-E-D"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-V-E-S-V-P-M-T-R-E-G-Y-N-K-I-K-A-E-I-N-R-M-E-N-E-E-M-P-M-I-V-Q-K-I-A-E-A-R-E-E-G-D-L-K-E-N-A-E-Y-H-A-Q-R-E-N-Q-G-M-L-M-A-K-I-N-E-L-R-D-K-I-A-R-A-S-I-I-D-V-S-S-L-P-K-D-E-V-V-F-G-C-T-V-T-V-E-D-V-A-Y-G-D-E-E-Q-F-T-L-V-G-A-G-D-E-D-Y-D-S-G-K-I-L-V-T-S-P-F-G-Q-G-L-V-G-K-K-V-G-E-T-A-E-V-D-V-P-A-G-K-L-K-F-K-I-L-K-I-E-F-N-L"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-E-P-P-V-K-I-N-C-P-T-C-G-R-R-F-L-S-D-E-T-P-A-M-P-F-C-S-K-R-C-Q-L-I-D-L-G-R-W-M-N-E-E-I-G-L-P-H-E-G-D-P-G-D-A-P-V-E-Y-L-D-D-R-D-L-T-Q-P-S-P-E-R-Q-N-E-S-F-H-R-Y-S-E"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-K-K-K-R-N-P-S-A-E-E-A-G-D-G-E-Q-T-A-A-E-L-G-D-F-E-T-T-L-G-D-V-E-T-I-V-R-K-L-E-S-G-A-L-T-L-D-D-S-L-K-Q-Y-E-V-A-V-A-K-M-R-Q-C-Y-Q-L-L-D-V-A-E-R-K-I-S-V-L-A-G-V-D-A-E-G-R-P-V-T-E-P-L-E-N-M-S-G-G-E-S-L-V-Q-K-Q-A-S-R-G-K-R-R-G-A-V-A-P-D-H-S-A-S-D-T-T-G-V-D-S-A-D-L-D-S-A-E-D-D-E"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-V-E-P-T-V-A-T-Y-N-T-S-D-F-R-K-G-L-K-V-Q-I-D-G-E-P-Y-L-I-T-E-M-N-F-V-K-P-G-K-G-N-A-M-Y-K-C-K-M-K-N-L-I-R-G-T-T-L-D-R-T-Y-K-G-G-D-S-L-E-A-A-D-V-E-T-T-T-V-Q-F-L-Y-R-Q-G-Q-D-Y-V-F-M-D-G-T-T-F-E-Q-Y-E-V-P-N-E-V-A-G-D-I-W-K-Y-L-K-D-G-T-E-C-S-M-T-L-Y-N-G-A-A-I-I-V-E-P-P-Q-H-V-Q-L-E-V-T-E-C-G-P-G-T-K-G-D-T-A-T-N-V-T-K-P-A-M-V-E-T-G-A-E-F-N-V-P-G-F-I-K-E-G-N-I-I-K-I-N-T-L-N-N-E-Y-V-E-R-V-N-N"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-S-I-E-E-R-V-V-D-I-V-S-E-Q-L-G-V-D-K-D-K-I-T-R-E-T-S-F-V-N-D-L-G-A-D-S-L-D-T-V-E-L-V-M-E-L-E-E-E-F-D-I-S-I-P-D-D-S-A-E-K-I-Q-K-V-G-E-A-I-D-F-I-E-K-E-K-G-E-D-A"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-T-D-Q-I-Y-Y-E-T-M-Y-I-L-R-P-D-I-A-E-D-E-V-T-N-H-I-D-K-Y-N-K-L-L-E-E-S-G-G-K-I-L-D-S-Q-M-R-G-K-R-R-L-A-Y-Q-I-A-K-H-R-E-G-I-Y-V-Q-L-S-H-Q-G-D-G-Q-H-I-F-K-I-E-K-A-M-R-L-S-E-D-V-I-R-Y-L-T-V-K-Q-E-G-P-L-P-T-P-R-S-S-N-K-G-Y-N-Q-S-E-K-K-D-I-E-S-I-D-S-T-N-K-S-E-F-K-E-E-A-N-D-K-K-T-A-T-S-E-S-T-S-S-Q-G-K-E-S-Q-K-S"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-K-R-V-K-V-V-L-T-E-S-V-A-T-L-G-R-D-G-D-V-V-E-V-A-P-G-Y-A-R-N-F-L-L-P-F-G-K-A-A-N-V-T-P-S-I-L-K-Q-I-E-R-K-R-A-K-E-K-I-A-A-E-K-V-K-Q-E-A-I-D-F-K-T-A-L-A-T-I-G-R-F-T-I-K-K-Q-V-G-E-D-G-V-L-F-G-T-V-T-N-G-D-V-A-E-A-I-E-A-A-T-K-K-D-I-D-R-R-D-I-T-V-P-D-I-H-N-L-G-S-F-V-A-K-I-K-L-H-Q-E-V-S-A-E-V-N-I-E-V-T-S"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-N-I-A-R-K-R-R-N-K-I-L-N-L-A-K-G-F-R-G-G-N-K-N-L-F-R-T-A-N-Q-R-V-M-K-A-L-C-N-A-Y-R-D-R-R-R-R-K-R-D-F-R-R-L-W-I-S-R-I-N-A-S-A-R-I-N-G-T-N-Y-S-R-L-I-N-G-M-K-N-S-E-I-I-I-N-R-K-M-L-A-Q-L-A-L-S-D-P-Q-C-F-E-K-I-V-S-T-V-N-N"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-I-F-E-G-S-F-T-N-A-S-T-L-K-V-G-I-V-V-A-R-F-N-D-L-I-T-N-K-I-L-S-G-C-L-D-C-L-K-R-H-G-L-D-T-S-E-T-S-K-E-L-D-I-V-W-V-P-G-S-F-E-L-P-I-A-A-K-T-L-L-K-K-T-N-Y-D-V-V-I-A-L-G-A-V-I-R-G-E-T-S-H-Y-D-V-V-I-S-E-A-S-K-G-I-S-Q-V-S-Y-E-N-N-V-P-I-I-F-G-V-L-T-T-D-S-M-Q-Q-A-L-E-R-A-G-I-K-N-N-L-G-W-N-Y-A-L-Q-A-I-E-M-G-S-L-I-K-N-L-N"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-E-L-D-G-F-I-Y-I-L-V-G-S-T-F-G-L-I-V-R-M-F-I-K-Y-I-S-G-K-K-K-I-F-Y-S-N-N-I-L-I-V-N-V-L-A-S-L-F-L-G-I-F-E-G-L-N-I-T-N-K-N-L-I-L-F-I-F-V-G-F-L-G-C-F-S-T-F-S-S-F-I-Y-Q-L-F-N-L-I-R-E-K-K-Y-L-I-L-L-I-Y-Y-A-E-V-I-L-L-S-F-L-F-F-C-L-G-Y-F-I-T-L-T-F-I-N"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-K-K-Y-L-L-T-F-L-L-T-A-Y-C-A-T-F-L-R-F-Y-F-K-N-N-F-V-I-S-I-I-G-S-F-L-Y-G-F-F-I-S-R-K-I-S-K-S-K-K-E-I-L-F-S-G-F-F-A-C-F-T-S-F-S-G-F-V-H-F-L-Y-Q-F-I-I-Q-G-Y-Y-L-K-L-F-I-Y-L-N-V-I-V-I-L-N-L-I-I-M-Y-I-G-F-Q-L-S-R-K-I-T"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-F-F-G-E-R-F-F-T-T-A-M-A-K-V-S-N-K-A-N-K-I-I-K-K-E-A-V-F-K-R-L-S-E-N-R-Y-A-K-F-Q-Y-E-I-L-E-T-I-E-A-G-I-E-L-L-G-T-E-V-K-S-I-R-N-G-S-V-N-L-R-D-G-Y-C-S-F-R-D-G-E-I-L-L-L-N-V-H-I-S-P-H-K-N-V-G-P-F-F-N-H-D-P-L-R-N-R-K-L-L-L-H-K-K-E-I-V-K-L-K-Y-N-T-E-K-K-G-L-T-I-I-P-L-S-I-Y-L-K-G-S-W-I-K-L-T-I-G-I-G-K-G-K-K-L-H-D-K-R-Q-A-D-K-Q-R-D-I-K-R-E-I-K-T-A-L-K-R"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-Q-E-E-I-L-Q-K-V-C-S-I-V-S-E-Q-L-S-V-E-S-A-E-V-K-S-D-S-N-F-Q-N-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-A-F-D-I-E-I-P-D-E-A-A-E-G-I-A-T-V-G-D-A-V-K-F-I-E-E-K-K-G"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-I-N-H-N-E-W-L-I-V-G-L-I-T-S-P-Q-G-I-N-G-K-I-K-I-K-S-L-S-D-F-E-E-R-F-T-K-P-G-K-R-W-I-Q-K-G-N-E-T-P-I-E-F-E-L-T-H-G-F-K-K-P-G-K-E-S-F-I-I-T-F-K-G-I-N-N-R-T-Q-A-E-N-L-K-G-Q-K-I-L-V-K-V-D-A-I-P-K-L-S-H-G-E-Y-H-L-T-E-L-I-N-L-N-V-K-I-S-E-N-N-Q-L-H-I-I-G-K-V-I-N-L-S-N-E-K-N-N-L-L-V-I-Q-L-L-K-N-N-K-E-V-L-I-P-F-V-K-E-I-V-P-I-V-D-I-K-K-N-F-I-L-L-T-P-P-S-G-L-L-E-L"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-P-L-L-L-T-G-K-K-F-H-N-D-L-N-K-N-K-C-L-A-M-F-A-P-L-E-G-G-Y-E-T-R-L-L-R-R-M-R-A-K-G-F-K-T-Y-I-T-S-A-R-G-L-G-D-P-E-V-F-L-L-K-L-H-G-I-R-P-P-H-L-G-H-Q-S-I-G-R-N-G-A-L-G-E-V-Q-Q-V-I-P-Q-A-S-E-L-F-N-E-N-D-K-D-K-L-L-W-L-L-E-G-Q-V-L-S-Q-S-E-L-E-S-L-I-K-I-C-T-S-D-N-K-L-K-I-V-V-E-M-G-G-S-R-K-L-E-W-K-S-L-N-D-Y-I-L-N-E-F"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-R-L-F-D-S-R-L-A-D-I-I-R-K-P-V-I-T-E-K-A-T-N-A-L-D-L-N-Q-Y-T-F-E-V-D-H-R-A-A-K-P-Q-I-K-A-A-I-E-A-L-F-D-V-K-V-I-G-I-N-T-M-N-P-P-R-R-T-R-R-V-G-K-F-S-G-K-R-S-Q-I-K-K-A-I-V-R-L-A-E-G-D-K-I-Q-L-F-P-E-S"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-T-K-T-P-E-M-T-K-T-A-I-A-H-G-K-Y-I-R-G-S-A-S-K-V-R-R-V-L-D-Q-I-R-G-K-S-Y-R-D-A-L-I-M-L-E-F-M-P-Y-R-S-T-D-P-I-T-K-V-L-R-S-A-V-A-N-A-E-H-N-L-G-M-D-P-S-S-L-V-I-S-S-A-S-A-D-N-G-P-V-M-K-R-F-R-P-R-A-Q-G-R-A-F-S-I-K-K-Q-T-C-H-I-S-I-S-V-E-S-A-P-N-Q-T-N-T-E-A-Q-N"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-S-P-K-R-T-K-F-R-K-Q-H-R-G-R-M-K-G-I-A-S-K-G-N-T-I-A-F-G-Q-F-A-L-Q-A-Q-D-C-G-W-V-T-A-R-Q-I-E-A-S-R-R-A-M-T-R-Y-V-K-R-G-G-K-I-W-I-R-I-F-P-D-K-P-V-T-M-R-P-A-E-T-R-M-G-S-G-K-G-N-P-E-F-W-V-A-V-V-K-P-G-R-I-L-F-E-M-G-G-E-E-I-T-E-E-I-A-K-E-A-M-R-L-A-Q-Y-K-L-P-V-K-T-K-F-I-S-S-D-I-N-L-S-S-D-S-S-G-E-G-K-T-G-K-D-S-K-E-E-V-K-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-L-D-S-L-K-Q-K-K-N-F-K-R-I-K-M-R-I-K-T-G-D-L-V-K-V-I-N-G-K-E-K-G-K-T-G-E-V-L-K-T-I-P-L-E-N-R-V-V-V-K-G-V-N-L-R-T-K-H-V-K-P-S-Q-E-G-E-S-G-R-I-L-T-E-E-A-S-L-H-A-S-N-V-M-F-F-S-K-D-K-N-L-I-S-K-I-E-Y-F-I-D-K-E-G-V-K-K-R-R-L-K-K-T-G-E-L-I-D"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-L-K-T-R-Y-K-E-A-I-R-P-K-L-L-K-D-L-G-L-K-N-I-H-Q-V-P-K-V-I-K-V-N-V-N-R-G-L-G-E-A-A-S-N-S-K-A-L-E-A-S-L-N-E-M-A-T-I-T-G-Q-K-A-L-V-T-R-S-K-K-A-I-A-G-F-K-I-R-E-G-M-A-I-G-C-T-V-T-L-R-G-D-R-M-Y-S-F-L-E-R-F-I-N-L-A-L-P-R-I-R-D-F-R-G-V-N-P-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-S-F-D-K-I-D-S-I-R-G-M-D-I-T-I-V-T-S-A-S-T-D-Q-E-G-K-A-L-L-K-E-L-G-M-P-F-S-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-N-H-D-P-I-S-D-M-L-T-R-I-R-N-A-S-Q-K-K-H-T-S-T-A-I-P-A-S-K-M-S-L-S-I-A-K-V-L-Q-K-E-G-F-I-T-D-I-N-E-E-G-E-G-Y-K-S-Q-I-V-L-G-L-K-Y-S-G-K-N-K-F-P-T-I-R-S-M-Q-R-V-S-K-P-G-L-R-V-Y-K-N-T-K-G-L-P-K-V-L-G-G-L-G-V-A-I-V-S-T-S-K-G-V-M-S-D-R-D-A-R-K-Q-G-I-G-G-E-V-L-C-Y-V-Y"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-S-P-V-Q-I-P-E-K-V-S-V-D-I-K-G-L-S-I-T-V-K-G-P-K-G-E-L-K-R-L-M-P-E-G-V-N-F-D-Q-K-E-N-Q-I-V-V-T-P-A-T-T-K-R-Y-S-R-E-R-H-G-L-C-R-T-L-I-S-N-M-V-Q-G-V-T-E-G-Y-E-K-K-L-E-I-V-G-V-G-S-R-A-Q-V-K-G-K-N-L-V-V-S-A-G-Y-S-H-P-V-E-M-T-P-P-D-G-I-T-Y-K-V-E-S-N-T-N-V-T-V-S-G-I-D-K-E-I-V-G-N-E-A-A-K-I-R-S-I-R-P-P-E-P-Y-K-G-K-G-I-K-Y-Q-D-E-R-I-I-R-K-A-G-K-S-G-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-K-I-S-R-K-L-Q-T-Q-K-R-H-K-R-L-R-R-Y-L-I-G-S-T-A-R-P-R-L-A-V-F-R-S-N-N-H-I-Y-A-Q-V-I-D-D-D-A-Q-Q-T-I-C-S-A-S-T-V-D-K-E-L-K-E-D-K-E-K-L-S-S-N-C-S-S-S-S-I-V-G-K-L-L-A-K-R-A-M-K-K-G-V-K-E-V-I-F-D-R-G-G-N-L-Y-H-G-R-V-K-A-L-A-D-A-A-R-D-A-G-L-N-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-S-T-L-N-T-L-K-S-N-T-G-S-R-K-K-K-L-R-K-G-R-G-I-A-A-G-Q-G-A-S-C-G-F-G-M-R-G-Q-K-S-R-S-G-R-P-T-R-P-G-F-E-G-G-Q-M-P-L-Y-R-R-V-P-K-L-K-H-F-E-I-I-N-Q-K-N-F-S-I-V-N-L-S-K-L-S-E-F-K-E-S-E-V-V-N-I-D-S-L-V-K-K-K-L-L-F-K-P-K-F-P-L-K-I-L-G-N-G-E-V-K-V-K-L-K-V-Q-A-H-A-F-T-K-V-A-K-E-K-I-E-A-A-G-G-S-C-E-I-I-N-N-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-A-P-V-K-K-T-G-S-K-K-S-K-K-N-V-P-N-G-V-V-H-I-Q-S-T-F-N-N-T-I-V-S-I-T-D-T-S-G-H-V-I-S-W-S-S-A-G-A-S-G-F-K-G-A-R-K-G-T-P-F-A-A-Q-T-A-A-E-A-A-A-K-R-A-L-D-Q-G-M-R-Q-I-K-V-L-V-R-G-P-G-S-G-R-E-T-A-I-R-A-L-Q-V-A-G-L-E-I-T-L-I-R-D-V-T-P-L-P-H-N-G-C-R-R-P-K-R-R-R-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-N-K-T-I-T-P-S-I-E-T-I-E-R-N-W-F-L-V-D-A-K-D-K-T-L-G-R-L-S-T-E-I-A-A-V-L-R-G-K-N-K-P-T-F-T-P-H-L-D-T-G-D-F-V-I-V-V-N-A-E-K-V-E-V-T-G-K-K-A-S-Q-K-L-Y-R-R-H-S-G-R-P-G-G-M-K-V-E-K-F-E-S-L-Q-E-R-I-P-E-R-I-I-E-Q-A-V-K-G-M-L-P-H-N-S-L-G-R-Q-Q-F-K-K-L-K-V-Y-K-G-S-D-H-P-H-A-A-Q-N-P-V-L-L-N-S"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-P-K-S-E-I-H-P-K-W-Y-P-D-A-K-V-I-C-N-G-E-V-V-M-T-T-G-S-T-K-P-E-L-H-V-D-V-W-S-G-N-H-P-F-F-T-G-T-Q-K-I-L-D-T-E-G-R-V-D-R-F-M-K-K-Y-G-M-G-S-A-D-S-A-T-S-K-E-T-K-E-S-K-K-S-D-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-N-A-A-V-K-R-P-V-L-P-D-P-Q-F-N-S-R-L-A-S-M-M-I-S-R-L-M-K-H-G-K-K-S-T-A-Q-K-I-L-S-D-A-F-S-L-I-S-E-R-T-G-G-N-A-V-E-L-F-E-T-A-V-K-N-A-T-P-L-V-E-V-R-A-R-R-V-G-G-A-T-Y-Q-V-P-M-E-V-R-Q-E-R-G-T-A-M-A-L-R-W-L-V-T-F-S-R-G-R-N-G-K-S-M-S-Q-K-L-A-G-E-L-M-D-A-A-N-E-T-G-S-A-V-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-Y"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-T-A-S-L-T-Q-Q-K-I-R-I-R-L-K-A-F-D-R-R-M-L-D-L-S-C-D-K-I-I-Q-T-A-D-T-T-A-A-S-A-I-G-P-I-P-L-P-T-K-R-K-I-Y-C-V-L-R-S-P-H-V-D-K-D-S-R-E-H-F-E-T-R-T-H-R-R-I-I-D-I-Y-S-P-S-A-K-T-I-D-A-L-M-K-L-D-L-P-S-G-V-D-I-E-V-K-L"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-D-K-E-C-K-S-N-L-E-S-L-L-Q-G-V-A-K-E-F-N-L-K-I-H-S-L-D-I-L-T-N-Q-N-P-I-I-V-K-I-I-I-C-K-T-N-K-D-D-I-T-L-D-D-C-S-R-F-N-N-P-A-I-S-V-I-E-N-S-N-L-L-N-C-S-Y-V-L-E-I-S-S-Q-G-V-S-D-E-L-T-S-E-R-D-F-K-T-F-K-G-F-P-V-N-V-E-L-N-Q-K-N-S-Q-I-K-F-L-N-G-L-L-Y-E-K-S-K-D-Y-L-A-I-N-I-K-G-K-I-K-K-I-P-F-N-E-V-L-K-V-S-L-C-T-F-K-D"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-L-A-F-D-F-F-G-A-T-E-G-G-L-F-D-I-N-A-T-L-P-L-M-A-I-Q-V-V-A-L-T-Y-I-L-N-S-L-F-F-K-P-V-G-N-V-V-E-K-R-E-K-F-V-S-N-N-I-M-D-A-K-N-K-L-S-E-V-E-K-L-E-A-D-L-L-S-Q-L-Q-S-A-R-Y-E-A-Q-K-I-V-S-E-A-E-N-E-S-D-K-L-Y-K-E-A-L-A-L-A-N-D-E-A-N-A-S-K-E-K-A-R-L-E-I-E-N-Q-T-S-S-A-R-D-Q-L-F-K-Q-A-D-D-L-S-E-L-I-V-N-R-L-I-L-E-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-L-P-L-L-A-T-E-G-F-G-L-N-L-N-L-F-E-T-N-V-L-N-W-A-V-V-V-F-G-L-Y-K-F-L-P-G-F-L-G-K-M-L-Q-K-R-R-E-G-I-L-L-E-L-K-D-A-E-D-R-L-L-K-A-T-Q-A-L-E-K-A-K-T-D-L-S-L-A-E-E-K-A-G-Q-I-K-A-D-S-L-K-R-S-E-S-I-R-M-E-S-E-K-K-A-I-E-E-M-A-R-I-K-Q-S-A-I-S-D-E-S-S-E-A-S-R-A-I-S-Q-L-R-K-E-A-V-E-L-A-I-K-K-A-L-D-S-L-P-N-R-L-D-Q-T-T-Q-E-N-L-V-T-Q-S-I-N-N-I-E-M-N"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-P-L-L-N-S-V-T-T-P-Y-A-E-A-L-L-Q-V-V-S-E-N-D-Q-T-E-E-M-V-K-E-V-K-Q-L-L-S-L-I-N-D-S-P-D-L-E-K-T-L-S-S-P-V-L-E-T-D-T-K-K-K-I-I-I-E-I-F-S-E-K-I-N-S-S-L-L-N-F-L-K-L-L-A-D-R-Q-R-I-G-I-V-T-S-I-L-D-R-F-L-E-I-Y-R-E-N-S-N-I-A-L-A-T-V-T-S-A-V-E-L-T-D-D-Q-K-G-L-I-T-K-K-I-I-N-I-A-G-T-E-K-L-E-L-V-T-K-I-D-P-S-L-I-G-G-F-V-A-S-V-G-S-K-V-I-D-A-S-L-A-S-Q-I-R-K-L-G-L-S-L-S-K"} +{"text": "### FUNCTION Probably a ribosomal protein or a ribosome-associated protein ### SEQUENCE -M-M-G-A-N-A-V-L-A-A-A-K-I-D-E-D-G-V-P-T-G-Y-T-P-K-P-D-E-G-R-F-I-I-K-I-L-W-L-P-D-N-V-A-L-A-V-D-Q-I-V-G-G-G-S-S-P-L-T-A-Y-Y-F-W-P-R-D-D-A-W-E-K-L-K-S-E-L-E-N-K-S-W-I-T-D-N-E-R-V-E-I-L-N-K-A-T-E-V-I-N-Y-W-Q-E-E-G-K-T-K-K-L-E-E-A-K-L-K-F-P-E-V-A-F-C-G-T-A"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-N-V-S-N-N-S-N-M-D-H-N-D-L-A-K-R-G-E-S-L-I-R-K-S-T-N-R-Y-L-T-T-V-R-I-A-F-R-A-K-Q-R-R-F-D-D-F-D-G-L-L-E-E-S-A-I-K-P-V-Q-R-S-I-I-E-L-S-D-E-Q-D-Q-P-D-L-L-P-G"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-T-S-S-K-K-P-S-N-S-S-A-K-N-E-N-L-Y-A-I-A-E-T-S-G-Q-Q-F-W-F-E-V-D-K-Y-Y-D-I-D-R-L-N-A-K-E-K-D-K-I-T-I-D-K-I-L-L-I-K-D-K-D-N-I-S-L-G-Q-P-Y-V-K-N-A-K-I-E-L-E-V-V-S-H-K-R-D-K-K-I-I-V-Y-K-M-R-P-K-K-K-T-R-R-K-M-G-H-R-Q-E-L-T-R-V-M-V-K-S-I-S-I-T-N-S-T-P-K-T-S-S-K-T-E-V-K-K-K-S-T-S-P-K-A-S-N-P-E-N"} +{"text": "### FUNCTION Component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria ### SEQUENCE -M-V-A-R-K-T-Y-I-L-K-L-Y-V-A-G-N-T-P-N-S-M-R-A-L-N-T-L-K-E-I-L-E-N-E-F-K-G-V-Y-A-L-K-V-I-D-V-L-K-Q-P-Q-L-A-E-E-D-K-I-L-A-T-P-T-L-A-K-I-L-P-P-P-V-R-R-I-I-G-D-L-S-D-R-E-K-V-L-I-G-L-D-L-L-F-D-E-L-S-E-S-E-Y-S-G-G-T-K-N"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-Q-S-N-L-S-S-F-N-K-I-E-Q-K-I-N-G-S-R-K-I-S-N-Y-L-I-G-G-M-L-S-I-G-G-I-G-F-I-L-A-A-I-S-S-Y-T-G-R-D-L-L-P-L-G-N-P-S-T-L-L-F-I-P-Q-G-I-I-M-G-A-Y-G-V-I-A-N-L-L-N-I-Y-L-W-Y-L-V-F-I-N-F-G-S-G-Y-N-F-F-D-K-D-S-Q-S-V-E-I-K-R-K-G-L-F-K-D-I-E-V-K-L-S-F-D-E-I-K-S-V-K-L-D-I-S-E-G-F-N-P-R-R-R-I-A-L-V-L-K-G-R-K-K-P-L-P-L-S-G-A-G-E-L-K-P-L-L-Q-V-E-E-E-G-A-R-L-A-K-F-L-N-V-N-L-E-G-L-K"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-E-I-L-N-E-L-I-S-T-Y-K-D-H-P-K-E-G-I-D-F-K-D-V-L-E-I-V-Q-H-P-I-V-F-K-E-L-I-L-K-M-A-S-S-K-I-V-S-N-A-E-A-L-I-S-I-D-A-R-G-F-I-F-G-S-A-I-S-F-Q-V-S-K-P-M-I-F-A-R-K-P-G-K-L-P-G-E-L-I-K-K-K-Y-T-L-E-Y-G-E-N-S-L-S-I-Q-K-K-S-L-N-N-F-Y-S-F-A-I-I-D-D-L-L-A-T-G-G-T-V-N-C-V-S-N-I-L-K-D-N-G-K-K-I-T-G-L-L-T-V-V-E-L-I-E-L-E-G-R-S-K-F-D-F-P-V-E-S-W-L-K-C-K"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-I-T-F-T-K-P-L-S-K-L-I-G-H-F-E-K-F-P-G-I-G-P-R-T-A-Q-R-L-A-L-F-I-L-K-Q-P-E-S-S-I-R-D-F-S-K-A-L-L-E-A-H-S-N-V-G-H-C-K-K-C-F-N-L-T-S-E-E-E-C-E-I-C-R-N-T-E-R-N-Q-K-I-I-C-V-V-A-E-T-K-D-L-L-A-L-E-R-S-R-E-F-K-G-T-Y-H-V-I-G-G-L-I-S-P-M-D-S-I-S-P-E-L-L-E-I-R-S-L-V-E-R-V-S-K-S-D-I-D-E-I-I-L-A-L-T-P-S-V-E-G-D-T-T-S-L-Y-I-G-K-L-L-T-P-F-T-K-V-T-R-I-A-Y-G-L-P-M-G-S-E-L-E-Y-V-D-E-V-T-L-A-R-A-L-E-G-R-T-N-L-I"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-I-E-P-L-L-C-G-I-V-L-G-L-V-P-I-T-L-L-G-L-F-V-S-A-W-N-Q-Y-R-R-G-S-G-M-L-D-M-D"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-S-N-K-K-E-I-V-V-T-D-W-I-K-Q-N-C-H-E-G-N-F-L-N-L-T-L-S-S-D-Q-R-R-V-F-R-G-K-R-K-S-D-C-N-Q-E-L-Q-L-Q-L-P-R-E-G-K-L-N-D-G-D-I-L-L-T-N-Q-K-K-L-F-V-Q-I-I-A-Q-K-E-N-L-I-K-I-T-A-K-T-S-I-E-L-I-K-V-A-Y-H-L-G-N-R-H-V-E-I-E-I-N-E-N-I-L-F-T-K-S-D-Y-I-I-E-E-L-L-R-N-F-D-V-V-Y-S-K-V-E-K-K-F-F-P-E-I-G-A-F-H-H-E-K-K-S-L-S"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-L-Q-T-N-R-L-S-I-N-A-I-G-K-I-K-K-N-W-I-R-E-G-I-N-Q-Y-K-K-R-M-P-D-L-I-I-N-E-S-K-S-F-N-I-D-N-I-R-V-N-N-I-I-I-C-L-T-E-E-G-Q-S-F-N-S-I-E-L-T-S-L-L-L-N-F-K-N-K-K-I-N-F-L-I-G-D-A-D-G-I-P-S-D-I-K-D-K-S-N-L-L-L-S-L-S-P-L-T-F-P-H-E-L-A-R-L-I-L-I-E-Q-I-Y-R-A-I-S-I-S-N-N-S-P-Y-H-R-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-K-Y-C-K-P-K-S-K-S-I-L-S-L-D-V-G-L-K-R-I-G-L-A-Y-C-D-S-L-F-I-T-V-N-I-L-P-A-L-K-R-E-R-N-N-N-E-I-I-I-I-K-E-H-I-K-K-H-N-L-T-G-F-I-V-G-L-P-L-D-E-A-G-G-M-T-S-Q-A-L-D-C-K-T-Y-G-E-F-L-F-N-E-L-K-L-P-F-S-F-V-N-E-H-S-S-T-W-E-S-T-N-R-F-G-V-K-K-D-K-S-G-L-I-D-S-L-S-A-K-I-I-L-E-Q-W-I-Q-E-G-P-E-L-K-E-L-V-G-N-K-Q-I"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-I-P-L-V-L-E-E-S-G-G-S-E-R-V-F-D-I-Y-S-R-L-L-R-E-R-I-I-F-L-G-E-Q-V-T-S-D-T-A-N-R-I-V-A-Q-L-L-F-L-E-A-E-D-P-E-K-D-I-Y-M-Y-I-N-S-P-G-G-S-V-Y-D-G-L-G-I-F-D-T-M-Q-H-V-K-P-D-I-H-T-V-C-V-G-L-A-A-S-M-G-A-F-L-L-A-A-G-T-K-G-K-R-S-S-L-R-H-S-R-I-M-I-H-Q-P-L-G-G-A-R-G-Q-A-S-D-I-R-I-Q-A-D-E-I-L-Y-L-K-E-R-L-N-T-E-L-S-E-R-T-G-K-E-L-E-T-I-K-G-D-T-D-R-D-F-Y-M-S-P-Q-E-A-V-E-Y-G-L-I-D-L-V-L-D-K-K-P-V-K-N-I"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-M-I-F-Q-I-G-W-A-A-L-A-A-I-F-T-F-S-I-A-M-V-V-W-G-R-N-G-D-G-S-I-D-I"} +{"text": "### FUNCTION Probably forms vertices in the carboxysome, a polyhedral inclusion where RuBisCO Has not been identified in purified carboxysomes ### SEQUENCE -M-V-C-T-Q-R-V-A-G-L-G-H-M-N-L-R-I-L-E-N-N-K-G-K-K-V-V-A-V-D-P-V-G-A-R-E-G-N-W-V-F-T-A-S-G-S-A-A-R-F-A-C-P-N-P-E-V-Q-T-D-L-T-I-G-G-I-I-D-Y-W-E-S-N"} +{"text": "### FUNCTION Probably forms vertices in the carboxysome, a polyhedral inclusion where RuBisCO Has not been identified in purified carboxysomes ### SEQUENCE -M-L-I-C-K-V-L-K-P-L-V-S-T-N-R-I-P-G-F-E-H-K-H-L-Q-V-V-L-D-G-S-S-N-K-V-A-V-D-A-V-G-C-K-P-G-D-W-V-I-C-V-G-S-S-A-A-R-E-A-A-G-S-K-S-Y-P-S-D-L-T-I-V-G-I-I-D-H-W-D-P-D-S-P-K-Q-I-E-V"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-K-E-Q-E-I-Q-S-S-M-N-K-S-V-E-A-T-Q-R-N-F-N-T-I-R-T-G-R-A-N-A-S-L-L-D-R-I-S-V-E-Y-Y-G-A-E-T-P-I-K-S-L-A-S-I-S-T-I-D-S-Q-T-I-S-I-Q-P-F-D-I-S-S-L-Q-T-I-E-K-A-I-S-V-S-D-L-G-I-T-P-N-N-D-G-K-V-I-R-I-N-V-P-P-L-T-E-E-R-R-K-E-F-C-K-L-A-S-K-Y-A-E-E-G-K-V-A-L-R-N-I-R-R-D-A-V-D-K-E-K-K-D-E-K-E-G-L-I-S-K-D-V-S-R-D-N-Q-L-E-I-Q-K-F-T-D-K-Y-I-S-L-I-E-T-K-L-S-E-K-E-K-E-I-L-K-V"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-I-I-E-H-K-M-A-K-E-K-Q-E-T-E-L-E-I-T-N-E-T-D-T-T-T-E-L-T-V-E-K-Q-G-K-E-L-I-A-Q-T-N-L-S-S-S-N-L-I-K-E-F-E-R-E-Q-L-K-K-Q-L-P-E-I-Y-V-G-D-T-V-K-V-G-V-K-I-T-E-G-N-K-E-R-V-Q-P-Y-E-G-V-V-I-A-K-R-H-G-G-L-H-Q-T-I-T-V-R-R-I-F-Q-G-I-G-V-E-R-V-F-M-L-H-S-P-Q-V-A-S-L-K-V-E-R-R-G-K-V-R-R-A-K-L-F-Y-L-R-D-R-V-G-K-A-T-R-V-K-Q-R-F-D-R"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-L-K-I-F-N-T-K-F-I-R-S-A-P-V-V-A-A-V-W-L-S-L-T-A-G-I-I-I-E-F-N-R-F-F-P-D-L-L-F-H-P-M-S"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-K-N-L-K-K-L-I-I-I-T-G-P-S-G-V-G-K-G-T-V-I-K-E-L-L-D-R-N-K-D-I-W-L-S-I-S-A-T-T-R-N-P-R-V-G-E-K-D-D-L-N-Y-Y-F-I-G-E-E-R-F-K-D-M-I-D-K-K-E-F-L-E-W-A-Q-F-A-G-N-Y-Y-G-T-P-L-S-T-V-N-E-K-I-E-K-G-F-I-V-L-L-E-I-E-V-E-G-A-K-Q-I-K-E-K-F-P-E-S-L-S-I-F-L-L-P-P-S-K-E-E-L-E-K-R-I-R-N-R-G-T-E-K-E-E-A-I-D-R-R-L-S-R-A-N-Y-E-I-A-S-S-N-Q-F-D-F-V-L-T-N-H-D-V-D-E-T-V-K-E-V-L-K-I-I-K-S"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-L-I-S-R-L-K-A-V-V-A-G-D-D-F-L-D-D-D-F-D-E-L-D-Y-A-S-E-D-E-F-N-G-N-D-D-L-K-Q-N-Y-K-K-S-N-A-L-S-N-S-N-P-F-E-F-M-N-N-N-R-T-S-N-V-V-G-M-P-G-I-A-N-S-S-S-E-V-N-L-M-E-P-R-S-F-D-E-M-P-Q-A-I-Q-A-L-R-E-R-K-T-V-I-L-N-L-T-M-M-D-P-D-Q-A-Q-R-A-V-D-F-V-A-G-G-T-Y-A-I-D-G-H-Q-E-R-V-G-E-S-I-F-L-F-A-P-S-C-V-N-V-T-S-S-F-P-E-E-A-S-P-S-N-V-S-S-K-K-T-S-Q-Y-K-F-E-T-N-T-T-P-E-P-A-W-G-E-S-K-L-S-A-Y-N"} +{"text": "### FUNCTION Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide ### SEQUENCE -M-T-L-P-S-L-T-K-L-L-L-K-A-K-K-E-K-N-L-S-F-E-D-L-G-N-L-I-N-R-D-E-V-W-V-A-S-L-F-Y-G-Q-A-T-A-S-E-E-E-A-T-S-L-I-A-A-L-D-L-T-S-D-L-K-E-D-L-S-T-P-P-V-K-G-C-L-D-P-V-I-P-T-D-P-L-I-Y-R-F-Y-E-I-M-Q-V-Y-G-L-P-M-K-D-V-I-Q-E-K-F-G-D-G-I-M-S-A-I-D-F-S-I-E-V-D-K-V-E-D-P-K-G-D-R-V-L-V-K-M-C-G-K-F-L-P-Y-K-K-W"} +{"text": "### FUNCTION Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase ### SEQUENCE -M-A-I-S-R-G-D-L-V-R-V-K-R-P-E-S-Y-W-Y-N-E-I-G-K-V-A-S-V-D-T-T-G-I-K-Y-N-C-V-V-R-F-E-K-V-N-Y-A-G-I-S-G-T-E-G-G-A-N-T-N-N-F-A-E-S-E-L-E-K-A"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-M-T-L-R-D-L-I-N-K-L-L-G-R-E-T-A-S-A-N-T-A-R-E-R-L-Q-L-V-L-A-H-D-R-V-D-M-S-S-L-T-T-D-L-L-D-K-M-R-K-E-I-L-D-V-V-A-K-Y-V-E-I-D-F-E-E-V-A-V-S-L-E-T-E-D-R-M-T-A-L-V-A-N-L-P-I-K-R-T-L-T-G-E-I-E-F-K-K-N-E-D-T-Q-K-K-K"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-F-A-Y-V-L-I-L-T-L-A-V-V-T-L-F-F-A-V-A-F-R-D-P-P-K-F-D-R-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Q-C-P-T-C-Q-N-T-D-S-R-V-L-E-S-R-S-A-D-T-G-K-S-V-R-R-R-R-E-C-L-N-C-S-F-R-F-T-T-Y-E-R-V-E-T-M-P-I-S-V-I-K-K-D-G-S-R-E-L-F-N-K-D-K-L-V-T-G-I-S-R-A-C-E-K-T-T-F-S-R-E-S-I-I-N-F-V-D-S-I-E-S-Q-I-V-Q-D-S-N-K-D-I-K-S-S-Q-I-G-E-L-I-L-K-G-L-R-K-E-N-E-V-A-Y-I-R-Y-A-S-V-Y-R-K-F-N-G-V-K-D-F-V-S-T-L-E-S-L-K-G-S-S-K-N-E-L-A-S-I-L"} +{"text": "### FUNCTION Acts as a chromphore lyase, covalently attaching 3Z-phycoerythrobilin but not other chromophores tested While it can transfer 3E-PEB a non-physiological adduct is made Chromophore is bound to the lyase in a ratio of nearly 11 ### SEQUENCE -M-T-K-N-L-I-T-I-N-Q-F-I-Q-K-S-L-G-E-W-K-S-I-R-S-T-H-S-L-A-F-Q-E-V-E-N-S-T-S-K-I-E-I-K-E-L-E-S-N-N-K-N-V-L-G-L-L-E-K-Y-N-Y-T-S-K-P-S-F-I-A-L-S-I-S-W-K-A-I-S-D-W-E-I-D-Q-K-I-E-Q-D-K-T-I-L-L-F-L-P-K-D-K-N-K-G-I-V-L-R-N-K-G-Y-T-E-S-V-I-S-S-S-E-Y-L-I-D-E-N-E-N-L-N-I-K-T-I-Y-S-S-T-A-S-E-E-R-I-C-F-L-S-N-H-I-R-S-R-Y-S-V-I-R-N-N-E-N-N-T-V-I-Q-T-S-H-T-S-E-I-R-N-M-S-I-L-K-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-K-L-K-G-P-D-G-R-I-P-D-R-L-P-D-G-R-P-A-V-A-W-E-R-R-W-T-E-G-T-L-P-L-W-L-V-A-T-A-G-G-I-A-V-I-F-V-L-G-I-F-F-Y-G-S-Y-Q-G-V-G-A-G"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-Q-V-N-E-N-P-N-K-V-P-V-E-L-N-R-T-S-L-Y-L-G-L-L-S-V-L-V-L-G-I-L-F-S-S-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-L-N-T-F-A-E-L-P-E-A-Y-K-A-F-A-P-T-V-D-V-L-P-L-I-P-L-F-F-F-L-L-V-F-V-W-Q-A-A-V-G-F-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-A-L-K-I-S-V-Y-T-I-V-F-F-F-V-G-I-F-L-F-G-F-L-A-S-D-P-T-R-T-P-N-R-K-D-L-E-S-P-Q-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-Q-T-L-S-S-A-P-D-P-A-V-S-V-A-V-T-I-L-A-V-L-L-A-L-T-G-F-G-L-W-T-A-F-G-P-K-A-A-K-L-T-D-P-W-D-D-H-D-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-G-Q-K-T-A-L-G-T-L-L-K-A-I-G-N-S-G-Q-G-K-V-V-P-G-W-G-A-V-P-I-M-T-V-I-G-L-L-L-L-V-F-L-V-I-L-L-Q-I-Y-N-Q-S-L-L-L-Q-G-F-S-V-D-W-N-G-N"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-K-R-I-S-S-D-E-V-K-K-V-A-Q-L-A-R-L-E-L-N-E-S-E-I-N-Q-H-A-E-Q-L-E-K-I-L-E-Y-I-K-Q-L-E-K-I-N-T-E-D-I-P-C-T-T-R-A-I-E-V-V-N-V-L-R-K-D-E-K-K-N-Y-E-N-S-E-E-I-L-D-L-A-P-S-R-E-N-K-F-F-K-V-P-K-I-I-N-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-V-A-V-I-K-L-A-L-Q-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-A-F-C-K-E-Y-N-A-R-T-Q-D-K-A-G-F-V-I-P-V-E-I-S-V-F-E-D-R-S-F-T-F-I-T-K-T-P-P-A-S-V-L-I-T-K-A-A-G-I-E-K-G-A-G-E-S-S-K-G-S-V-G-N-I-S-K-S-Q-L-E-E-I-A-K-T-K-L-P-D-L-N-C-T-S-I-E-S-A-M-K-V-I-E-G-T-A-R-N-M-G-V-S-I-T-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-G-R-T-I-E-N-K-Q-K-I-V-T-E-I-K-S-L-L-D-D-S-E-M-A-V-V-L-D-Y-K-G-L-T-I-K-E-M-S-D-L-R-S-R-L-Q-T-N-N-G-I-C-K-V-T-K-N-S-L-M-R-K-A-I-D-G-N-S-N-W-T-D-L-E-S-L-L-T-G-T-N-A-F-V-L-I-K-E-D-V-G-G-A-V-K-A-I-Q-S-F-Q-K-E-T-K-K-S-E-T-K-G-A-L-F-E-G-R-L-L-S-E-S-E-I-K-E-I-A-S-L-P-S-R-E-V-L-M-A-K-I-A-G-A-L-N-G-V-A-T-K-I-A-I-S-I-N-E-V-P-S-G-I-A-R-S-L-K-Q-H-S-E-K-S-E-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-T-A-K-T-E-E-I-L-D-S-L-K-S-L-S-L-L-E-A-S-E-L-V-K-Q-I-E-E-A-F-G-V-S-A-A-A-S-A-G-V-V-M-A-A-P-G-A-G-G-G-D-G-D-G-G-A-A-E-E-K-T-E-F-D-V-I-L-E-S-F-D-A-A-A-K-I-K-V-L-K-V-V-R-N-A-T-G-L-G-L-G-D-A-K-A-L-V-E-S-A-P-K-T-V-K-E-G-I-A-K-A-D-A-E-T-L-K-K-E-I-E-E-A-G-G-K-V-T-L-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-Y-Q-K-D-L-Y-D-L-Q-I-D-L-V-F-K-C-N-D-F-S-N-L-S-N-H-F-I-N-K-S-D-N-I-I-F-E-S-G-F-W-E-E-V-L-L-C-W-I-K-I-I-L-D-E-K-D-T-S-F-P-N-F-I-L-Y-K-K-S-F-S-L-S-L-Q-I-I-N-D-N-E-I-S-S-I-N-Q-K-W-M-N-K-S-G-S-T-D-V-L-S-F-P-I-I-S-D-E-D-T-T-K-D-L-N-F-I-E-L-G-D-L-F-I-S-L-E-T-A-F-K-Q-S-L-E-F-N-H-S-I-K-K-E-M-L-W-L-A-S-H-G-L-L-H-L-L-G-W-E-H-N-D-D-Y-E-L-D-N-M-L-N-F-Q-E-Y-L-I-S-K-L-D"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA biosynthesis ### SEQUENCE -M-K-P-K-N-W-L-I-L-K-R-K-V-R-F-G-D-C-D-S-A-G-V-I-H-F-H-N-L-L-R-W-A-H-E-S-W-E-E-S-I-D-I-Y-G-I-P-H-Q-D-I-F-P-D-S-N-S-H-K-N-Q-I-I-C-P-I-V-N-C-E-A-N-F-L-S-P-I-K-I-G-D-L-L-S-I-K-I-F-P-K-K-I-N-N-H-L-F-Q-V-N-T-F-F-L-K-D-E-I-N-V-A-E-G-K-I-I-H-C-S-L-D-V-D-S-K-L-K-V-K-L-P-D-Q-L-E-R-W-I-E-A-S-N-I-N-T-N-L-K-E-C"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-E-K-M-L-L-K-S-T-T-R-H-V-R-I-F-T-A-D-V-I-N-N-D-L-V-F-H-P-N-K-L-T-L-D-L-D-P-D-N-E-F-I-W-N-E-D-S-L-K-K-V-N-Q-R-F-T-E-L-V-Q-E-R-A-G-K-S-L-D-D-Y-E-L-R-K-I-G-S-E-I-E-G-L-I-K-Y-L-L-Q-N-G-L-L-S-Y-N-P-E-C-R-V-M-N-Y-S-M-G-L-P-K-T-K-E-V-L"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-N-N-Q-N-R-D-N-F-I-D-K-A-F-T-V-I-A-E-S-I-V-K-I-M-P-I-A-D-K-E-K-K-A-Y-I-Y-Y-R-D-G-L-A-A-Q-N-N-G-D-Y-S-E-A-L-D-Y-Y-N-E-S-L-L-L-E-E-N-K-I-D-R-G-E-T-L-K-N-M-A-I-I-Y-M-S-N-G-E-E-D-R-S-I-E-T-Y-Q-K-A-L-E-E-N-P-K-Q-P-S-C-L-K-N-I-G-L-I-Y-E-K-R-G-R-F-A-E-Q-N-G-D-L-D-Q-R-D-M-W-F-D-K-A-A-Q-V-W-S-K-A-V-R-L-Y-P-G-G-Y-L-D-I-E-N-W-L-K-T-S-G-R-S-S-I-D-I-Y-L"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-N-N-Y-R-I-A-K-I-S-S-L-L-K-K-E-I-T-L-I-L-Q-N-D-L-E-N-D-L-L-R-S-N-F-I-N-I-S-K-I-E-L-S-G-D-L-Q-F-C-K-I-Y-I-T-S-T-A-E-E-A-I-R-K-E-I-V-E-E-L-N-L-A-K-T-Y-I-R-H-T-L-G-Q-R-I-E-M-R-R-V-P-E-M-T-F-K-D-D-T-V-L-E-K-G-L-S-V-L-K-L-L-A-E-L-K-N-K-K-H-N-Q-D-S-K-V-E-G-N-N-K-N-V"} +{"text": "### FUNCTION Involved in the binding and/or turnover of quinones at the Q site of Photosystem II ### SEQUENCE -M-I-Q-I-S-N-L-I-L-A-A-D-V-S-P-E-V-A-G-S-S-G-F-N-M-I-A-S-F-F-A-A-A-L-L-I-V-I-P-A-A-A-F-L-I-F-V-S-Q-K-D-S-L-E-R-T-S-A-T-R-R-R"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-S-N-D-F-R-T-G-T-T-I-E-I-D-G-Q-V-W-R-V-V-E-F-L-H-V-K-P-G-K-G-S-A-F-V-R-T-K-L-K-S-V-R-N-G-N-V-V-E-K-T-F-R-A-G-E-S-V-Q-Q-A-V-L-E-K-S-N-L-Q-H-T-Y-V-E-S-G-D-Y-V-F-M-D-M-I-S-F-E-E-T-R-L-S-S-D-Q-I-G-R-G-S-K-Y-L-K-E-G-M-E-V-N-V-I-F-Y-K-D-K-V-L-E-V-E-L-P-I-S-I-T-L-K-V-T-E-T-D-P-G-V-K-G-D-T-A-S-G-G-T-K-P-A-I-L-E-T-G-A-Q-V-M-V-P-L-F-I-S-V-G-E-M-I-K-V-D-T-R-N-D-S-Y-L-G-R-D-N"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-G-F-G-L-P-N-F-G-Q-L-T-E-A-F-K-K-A-K-E-I-Q-Q-N-A-Q-K-L-Q-D-E-L-E-S-M-E-I-E-G-K-S-D-D-E-M-I-K-V-W-I-S-G-N-Q-L-P-L-R-V-E-V-N-E-N-I-S-T-A-N-K-E-E-I-E-K-N-I-L-E-A-I-K-K-A-H-E-S-S-T-T-T-M-K-E-R-M-N-D-L-T-G-G-L-N-L-N-L-P-G-L-D-N-N-D-S"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-Q-Q-P-Y-Y-E-T-M-Y-I-L-R-P-D-I-P-E-E-E-V-E-T-H-V-T-K-Y-R-E-M-V-T-E-A-G-A-E-V-L-D-N-Q-M-R-G-K-R-R-L-A-Y-P-I-S-N-H-K-E-G-I-Y-V-Q-L-S-H-N-G-N-G-Q-Q-V-A-V-L-E-K-A-M-R-L-S-E-D-V-I-R-Y-L-T-V-K-Q-E-G-P-L-P-A-P-R-I-V-P-G-S-E-P-E-P-V-Q-Q-Q-E-A-A-A-V-E-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-K-R-V-Q-V-V-L-N-E-D-V-L-S-L-G-K-D-G-D-L-V-E-V-A-P-G-Y-A-R-N-F-L-L-P-F-G-K-A-V-P-V-T-P-A-V-M-K-Q-V-G-H-R-R-A-K-Q-A-E-H-Q-A-A-I-K-Q-E-A-L-D-F-Q-T-A-L-V-T-I-G-R-F-T-V-K-K-Q-T-G-E-D-D-V-L-F-G-T-V-T-N-G-D-V-A-E-A-I-E-T-A-T-K-K-E-I-D-R-R-N-I-I-V-P-E-I-H-R-T-G-S-Y-K-V-Q-V-K-L-H-N-E-V-N-A-E-I-N-L-E-V-V-S-Y"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-K-K-T-D-D-I-L-D-S-L-K-T-L-S-L-L-E-A-S-E-L-V-K-Q-I-E-D-A-F-G-V-S-A-A-A-S-A-G-V-V-V-A-A-G-G-A-A-G-G-G-A-A-A-E-A-A-E-E-Q-T-E-F-D-V-V-L-E-S-F-D-A-S-A-K-I-K-V-L-K-A-V-R-E-A-T-G-L-G-L-G-D-A-K-A-M-V-E-A-A-P-K-T-I-K-E-G-I-A-K-N-D-A-E-A-L-K-K-A-I-E-E-V-G-G-K-V-S-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-G-R-T-L-E-S-K-Q-Q-I-V-E-E-L-K-G-L-L-G-E-A-E-M-A-L-V-L-D-Y-Q-G-L-S-I-K-E-M-S-D-L-R-T-R-L-Q-A-S-N-G-V-C-K-V-T-K-N-T-L-M-R-H-A-I-N-G-N-G-A-W-S-N-L-E-S-L-L-T-G-T-N-A-F-V-L-I-K-G-D-V-G-G-A-V-K-A-V-Q-A-F-Q-K-D-T-K-K-S-E-T-K-G-G-L-F-E-G-K-L-L-S-Q-G-E-I-K-A-I-G-D-L-P-T-K-E-V-L-M-A-Q-I-A-G-S-L-N-A-L-A-T-K-V-A-V-G-I-N-E-V-P-S-G-L-A-R-A-L-H-Q-H-A-E-S-G-E-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-V-S-V-I-K-L-A-L-Q-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-A-F-C-K-E-Y-N-A-R-T-Q-D-K-A-G-L-V-I-P-V-E-I-S-V-F-E-D-R-S-F-T-F-I-T-K-T-P-P-A-S-V-L-I-T-K-A-A-G-I-E-K-G-S-G-E-S-A-H-G-K-V-G-S-L-S-R-S-Q-L-E-E-I-A-K-T-K-L-P-D-L-N-C-T-S-I-E-S-A-M-R-I-I-E-G-T-A-R-N-M-G-V-S-I-S-D"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-A-L-Q-T-S-P-I-N-L-D-L-D-L-A-F-H-P-A-N-D-D-A-L-T-S-L-V-D-A-D-T-K-R-R-L-T-H-A-S-P-W-Q-Q-D-L-T-A-W-I-E-S-V-R-R-D-P-T-L-T-C-P-E-I-V-R-L-S-P-M-L-S-L-G-L-Q-L-T-D-D-A-T-I-T-E-L-N-H-S-W-R-Q-R-S-E-S-T-D-V-L-S-F-P-A-L-D-N-S-L-V-L-P-T-D-T-C-V-E-L-G-D-I-V-V-S-V-Q-T-A-Q-R-Q-A-K-Q-H-S-H-E-L-G-L-E-L-R-W-L-V-S-H-G-L-L-H-L-L-G-W-D-H-P-T-D-Q-S-L-K-T-M-L-S-Y-Q-E-Q-L-L-S-I-N-G-K-V-H-H-H"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA biosynthesis ### SEQUENCE -M-N-P-E-N-W-L-L-L-R-R-V-V-R-F-G-D-T-D-A-A-G-V-M-H-F-H-Q-L-F-R-W-C-H-E-S-W-E-E-S-L-E-S-Y-G-L-N-P-A-D-I-F-P-G-S-R-K-S-E-V-T-P-E-V-A-L-P-I-I-H-C-Q-A-D-F-R-R-P-I-H-T-G-D-A-L-A-M-E-L-R-P-E-R-L-N-P-N-S-F-Q-V-H-F-E-F-R-C-E-E-Q-I-A-A-H-A-L-I-R-H-L-A-I-N-A-Q-T-R-H-R-C-A-L-P-E-G-I-D-R-W-L-E-A-S-G-V-G-K-I-G-S-I"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-N-E-T-L-L-K-C-T-T-R-H-V-R-I-F-T-A-R-V-E-N-N-D-L-V-P-D-P-N-Q-L-T-L-D-L-D-P-D-N-E-F-L-W-T-E-S-V-T-K-E-I-Q-Q-R-F-A-E-L-V-A-S-H-A-G-G-E-L-S-D-Y-N-L-R-R-I-G-S-E-L-E-G-T-I-R-K-L-L-Q-A-G-K-L-S-Y-N-P-E-C-R-V-L-N-Y-S-M-G-L-P-R-T-P-E-L-L"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-T-Q-N-K-D-N-F-I-D-K-T-F-T-V-M-A-D-L-I-V-K-M-M-P-I-N-D-K-A-K-R-A-Y-V-Y-Y-R-D-G-L-S-A-Q-N-A-G-D-Y-A-E-A-L-E-N-Y-E-E-S-L-K-L-E-E-S-P-F-D-R-S-E-T-L-K-N-M-A-I-I-Y-M-S-N-G-D-E-D-L-A-L-D-T-Y-Q-R-A-L-D-Q-N-S-N-Q-P-S-C-L-K-N-M-G-L-I-Y-E-K-R-G-R-T-A-Q-E-A-G-L-Q-D-E-A-D-R-L-F-D-R-A-A-D-V-W-T-Q-A-V-R-L-Y-P-G-G-Y-L-D-I-E-N-W-L-K-T-T-G-R-S-N-I-D-V-Y-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-P-G-R-R-V-E-R-V-A-A-L-I-R-R-E-T-S-E-L-L-I-H-G-I-R-D-E-R-V-H-Q-G-M-V-S-I-T-N-V-E-V-S-G-D-L-Q-H-C-K-I-F-V-S-I-Y-G-E-E-I-Q-R-S-E-V-L-E-G-L-E-A-A-S-G-F-L-R-G-E-L-G-R-R-L-Q-M-R-R-A-P-E-V-H-F-H-L-D-R-G-I-E-K-G-T-S-V-L-N-L-L-E-Q-L-E-Q-Q-R-E-T-L-G-E-V-Q-S-E-S-D-Q-P-T-T-Y-E-T-T-T-V-N-K-T"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-Q-E-A-I-L-E-K-V-R-S-I-V-T-E-Q-L-S-V-E-A-G-E-V-K-P-E-S-S-F-Q-N-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-A-F-D-I-E-I-P-D-E-A-A-E-G-I-T-T-V-G-D-A-V-K-Y-I-E-D-K-Q-A"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-N-G-D-E-D-W-L-T-V-G-K-V-V-A-A-Q-G-M-Q-G-E-L-R-I-N-P-S-S-D-F-P-E-R-F-T-L-P-G-Q-R-W-L-K-E-R-N-G-E-P-R-P-I-E-L-L-T-G-R-Q-L-P-G-R-S-L-Y-V-V-K-F-A-G-V-N-N-R-N-A-A-E-A-L-V-G-Q-K-L-L-V-P-S-S-D-R-P-S-L-A-E-G-E-F-H-L-L-D-L-V-G-L-E-A-R-L-Q-A-E-G-P-A-I-G-H-V-I-D-L-T-T-A-G-N-D-L-L-E-I-E-L-L-T-G-R-R-V-L-V-P-F-V-E-A-I-V-P-E-V-Q-L-N-Q-G-W-L-R-L-T-P-P-P-G-L-L-E-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-T-K-L-K-G-P-D-G-R-I-P-D-R-L-P-D-G-S-P-A-V-S-W-E-R-R-W-T-E-G-S-L-P-L-W-L-V-A-T-V-G-G-M-A-V-L-S-V-L-G-L-F-F-F-G-S-F-T-G-V-G-S-A"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-E-Q-N-P-N-P-N-N-L-P-A-E-L-N-R-T-S-L-Y-L-G-L-L-L-V-F-V-T-A-V-L-F-T-S-Y-F-F-N"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-S-P-L-P-P-S-A-E-A-C-R-N-E-L-L-N-R-L-A-R-E-A-Y-R-H-G-D-F-T-L-A-S-G-R-Q-S-N-H-Y-V-N-C-K-P-V-S-L-S-G-S-G-L-A-L-L-G-L-A-L-L-K-Y-V-E-P-D-A-V-C-V-A-G-L-T-L-G-A-D-P-L-V-S-A-V-A-M-A-A-A-Q-A-E-R-T-L-N-A-L-I-V-R-K-Q-A-K-G-H-G-T-A-A-W-L-E-G-P-L-P-P-S-G-A-R-I-T-V-L-E-D-V-V-T-T-G-G-S-S-L-K-A-V-Q-Q-L-R-E-T-G-Y-L-V-T-R-V-V-T-I-V-D-R-Q-E-G-G-E-E-A-L-N-A-A-E-L-E-L-V-S-L-Y-Q-L-N-Q-V-A-E-R-A-R-Q-L-E-T-E-T"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-A-F-T-L-D-L-M-A-Q-L-P-E-A-Y-Q-A-Y-A-P-A-V-D-V-L-P-L-I-P-I-F-F-F-L-L-V-F-V-W-Q-A-S-V-G-F-R"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-A-L-K-L-S-V-Y-S-V-V-F-F-F-I-A-V-F-V-F-G-F-L-A-S-D-P-S-R-T-P-A-R-K-D-L-E-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-M-E-N-S-S-S-E-T-Y-S-L-L-I-A-M-V-T-I-T-F-G-L-T-G-Y-G-L-Y-T-A-F-G-P-P-S-K-E-L-E-D-P-F-E-E-H-E-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-Q-S-T-R-L-G-N-L-I-K-S-L-P-G-Y-A-P-G-K-V-V-P-G-W-G-T-T-P-V-M-A-G-I-G-F-M-L-L-I-F-L-V-T-I-L-Q-I-Y-N-Q-S-L-L-L-Q-S-I-S-F-E"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-T-A-I-A-Q-Q-K-I-R-I-R-L-K-A-F-D-R-R-M-L-D-L-S-C-D-K-I-I-E-T-A-D-N-T-A-A-T-A-I-G-P-I-P-L-P-T-K-R-K-I-Y-C-V-L-C-S-P-H-V-D-K-D-S-R-E-H-F-E-T-R-T-H-R-R-I-I-D-I-Y-N-P-S-A-K-T-I-D-A-L-M-K-L-D-L-P-S-G-V-D-I-E-V-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-N-A-A-E-K-R-P-V-L-P-D-P-Q-F-N-N-R-L-A-T-M-M-I-S-R-L-M-K-H-G-K-K-S-T-A-Q-R-I-L-A-Q-A-F-G-L-I-N-E-R-T-G-G-D-P-I-E-L-F-E-T-A-V-K-N-A-T-P-L-V-E-V-R-A-R-R-V-G-G-A-T-Y-Q-V-P-M-E-V-R-Q-E-R-G-T-A-M-A-L-R-W-L-V-N-F-S-R-A-R-N-G-R-S-M-S-Q-K-L-A-A-E-L-M-D-A-A-N-E-A-G-S-A-V-R-K-R-E-E-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-Y"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-P-K-P-D-I-H-P-N-W-Y-P-D-A-K-V-I-C-N-G-E-V-V-M-T-T-G-S-T-Q-P-E-L-H-V-D-V-W-S-G-N-H-P-F-F-T-G-T-Q-K-I-L-D-T-E-G-R-V-D-R-F-M-R-K-Y-G-M-G-S-A-D-A-A-A-D-E-K-K-P-D-A-K-N-N-N-K-D-N-T-S-K-E-D"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-N-K-T-S-V-P-S-I-D-S-I-E-R-Q-W-F-L-V-D-A-E-N-Q-T-L-G-R-L-A-T-E-V-A-S-V-L-R-G-K-N-K-P-S-F-T-P-H-L-D-T-G-D-F-V-V-V-V-N-A-D-K-I-R-V-S-G-N-K-A-N-Q-K-L-Y-R-R-H-S-G-R-P-G-G-M-K-V-E-T-F-Q-A-L-Q-D-R-L-P-E-R-I-V-E-K-A-I-K-G-M-L-P-H-N-A-L-G-R-Q-L-F-R-K-L-K-V-Y-R-G-P-E-H-P-H-S-A-Q-R-P-Q-T-L-Q-L-N-P-A-A-S-S-Q"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-P-T-K-K-T-G-S-K-K-T-K-R-N-V-P-N-G-V-A-H-I-Q-S-T-F-N-N-T-I-V-S-I-A-D-T-A-G-E-V-I-A-W-S-S-A-G-A-S-G-F-K-G-A-R-K-G-T-P-F-A-A-Q-T-A-A-E-A-A-A-R-R-A-L-E-Q-G-M-R-Q-I-E-V-L-V-R-G-P-G-S-G-R-E-T-A-I-R-A-L-Q-V-A-G-L-E-I-T-L-I-R-D-V-T-P-L-P-H-N-G-C-R-R-P-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-I-P-R-D-K-R-V-E-V-A-L-T-Y-I-Y-G-I-G-L-T-R-A-K-T-I-L-T-K-S-D-V-N-P-D-I-R-V-K-D-L-E-D-G-D-V-Q-K-L-R-T-A-L-E-A-F-T-I-E-G-D-L-R-R-Q-E-G-M-A-L-K-R-L-Q-D-I-G-C-L-R-G-R-R-H-R-M-S-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-R-G-A-R-K-T-V-A-G-K-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-T-L-R-L-D-S-L-K-A-N-V-G-A-R-R-R-K-M-R-K-G-R-G-I-A-A-G-Q-G-A-S-C-G-F-G-M-R-G-Q-K-S-R-S-G-R-P-T-R-P-G-F-E-G-G-Q-M-P-L-Y-R-R-V-P-K-L-K-H-F-T-T-V-N-S-K-E-F-T-V-V-N-V-A-A-L-N-E-L-K-A-G-S-T-I-N-L-D-T-L-V-K-N-G-V-V-T-S-P-K-Y-P-L-K-V-L-G-N-G-E-L-K-V-K-L-T-I-Q-A-A-A-F-T-A-T-A-R-S-K-I-E-A-A-G-G-T-C-E-I-L-D"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-N-P-I-P-I-P-D-K-V-A-V-T-L-D-G-L-A-V-S-V-K-G-P-K-G-E-L-S-R-T-L-P-E-G-V-S-V-S-Q-V-E-N-T-I-V-V-T-P-T-S-Q-K-R-K-S-R-E-R-H-G-L-C-R-S-L-V-A-N-M-V-E-G-V-S-K-G-Y-T-R-K-L-E-L-I-G-V-G-S-R-A-Q-V-K-G-K-K-L-V-V-S-A-G-F-S-H-P-V-E-M-D-P-P-E-G-V-T-F-A-V-E-N-N-T-N-V-T-V-S-G-A-D-K-E-L-V-G-N-E-A-A-K-I-R-A-I-R-P-P-E-P-Y-K-G-K-G-I-R-Y-E-G-E-R-I-L-R-K-A-G-K-S-G-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-A-N-H-D-P-I-S-D-M-L-T-R-I-R-N-A-S-E-K-R-H-Q-T-T-R-V-P-A-S-R-M-S-R-S-I-A-K-V-L-Q-Q-E-G-F-I-S-E-I-S-E-E-G-E-G-V-R-T-H-L-V-L-E-L-K-Y-S-G-K-H-R-H-P-T-I-R-S-M-Q-R-V-S-K-P-G-L-R-I-Y-K-N-T-R-A-L-P-K-V-L-G-G-L-G-M-A-I-I-S-T-S-K-G-V-M-S-D-R-D-A-R-K-Q-G-V-G-G-E-V-L-C-Y-V-Y"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-L-K-Q-R-Y-R-E-T-I-Q-P-K-L-L-K-D-L-S-L-S-N-I-H-E-V-P-K-V-L-K-I-T-V-N-R-G-L-G-E-A-A-Q-N-A-K-S-L-E-A-S-I-T-E-L-A-T-I-T-G-Q-K-V-V-V-T-R-A-K-K-A-I-A-G-F-K-I-R-Q-G-M-P-I-G-C-A-V-T-L-R-G-E-R-M-Y-A-F-L-E-R-L-I-N-L-A-L-P-R-I-R-D-F-R-G-V-S-P-K-S-F-D-G-R-G-N-Y-T-L-G-V-R-E-Q-L-I-F-P-E-I-S-F-D-K-I-D-A-I-R-G-M-D-I-T-I-V-T-S-A-R-T-D-E-E-G-Q-S-L-L-R-E-M-G-M-P-F-R-S-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-P-I-A-T-P-K-Q-K-T-T-Q-R-I-K-M-R-I-H-K-G-D-T-V-Q-V-I-T-G-K-D-K-G-K-T-G-E-V-L-R-T-L-P-I-E-N-R-V-I-V-Q-G-V-N-I-R-T-R-H-V-K-P-T-Q-E-G-E-S-G-R-I-V-T-E-E-A-S-V-H-A-S-N-V-M-L-Y-S-N-K-K-K-I-A-S-R-V-E-L-V-V-E-K-D-G-S-K-K-R-R-L-K-K-T-G-E-L-I-D"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-S-P-K-R-V-K-F-R-K-Q-Q-R-G-R-M-R-G-V-A-T-R-G-N-T-I-A-F-G-E-F-A-L-Q-A-Q-E-C-G-W-I-T-S-R-Q-I-E-A-S-R-R-A-M-T-R-Y-V-K-R-G-G-K-I-W-I-R-I-F-P-D-K-P-V-T-M-R-P-A-E-T-R-M-G-S-G-K-G-N-P-E-F-W-V-A-V-I-K-P-G-R-I-L-F-E-M-G-G-A-E-I-T-E-D-I-A-K-E-A-M-R-L-A-Q-Y-K-L-P-I-K-T-K-F-I-G-L-D-D-Q-E-K-V-A-G-S-D-K-P-A-S-V-P-A-I-T-A-E-S"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-T-T-S-S-P-T-T-T-T-I-A-K-A-H-G-R-F-I-R-G-S-V-S-K-V-R-R-V-L-D-Q-I-R-G-R-T-Y-R-D-A-L-I-M-L-E-F-M-P-Y-R-S-T-G-P-I-T-K-V-L-R-S-A-V-A-N-A-E-H-N-L-G-L-D-P-A-S-L-V-I-A-Q-A-S-A-D-M-G-P-S-M-K-R-Y-R-P-R-A-Q-G-R-A-F-A-I-K-K-Q-T-C-H-I-S-I-A-V-A-A-Q-T-D-S"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-E-R-F-N-D-R-L-A-D-V-I-R-R-P-L-I-T-E-K-A-T-S-A-L-E-Q-N-Q-Y-T-F-E-V-D-H-R-A-A-K-P-D-I-K-A-A-V-E-Q-L-F-D-V-R-V-V-G-I-S-T-M-N-P-P-R-R-S-R-R-V-G-R-F-T-G-K-R-A-Q-V-K-K-A-I-V-R-L-A-E-G-N-T-I-Q-L-F-P-E-S"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-P-L-L-L-S-G-R-V-F-R-R-D-L-D-A-C-G-C-L-A-M-H-V-P-L-E-G-G-S-E-T-R-L-L-R-R-L-R-A-A-G-Y-R-T-Q-L-S-S-A-R-G-L-G-D-P-E-V-F-L-F-E-L-H-G-I-R-P-P-H-L-G-H-Q-S-V-G-R-N-G-A-V-G-E-V-Q-Q-V-M-P-Q-L-A-E-L-F-V-D-N-A-P-V-V-L-W-L-L-E-G-Q-V-L-S-R-S-E-L-L-A-L-C-D-L-C-K-R-E-S-R-L-R-V-V-V-E-M-G-G-A-R-S-L-N-W-Q-P-M-S-T-L-L-G-D"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Q-C-P-S-C-Q-N-T-D-S-R-V-L-E-S-R-A-A-D-A-G-R-S-V-R-R-R-R-E-C-L-H-C-D-F-R-F-T-T-Y-E-R-V-E-T-V-P-I-T-V-L-K-R-N-G-N-R-E-T-F-N-R-S-K-I-L-N-G-L-T-L-A-C-Q-K-T-G-L-E-Q-D-R-L-E-S-M-V-N-E-L-E-L-Q-L-Q-Q-R-S-G-R-E-V-N-S-A-E-I-G-E-M-V-L-D-Q-L-S-E-M-S-E-V-A-Y-V-R-F-A-S-V-Y-R-D-F-R-G-V-N-D-F-V-A-A-L-E-G-I-H-A-N-K-E-Q-L-A-A-V-R"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-D-A-F-A-Y-T-L-L-M-T-L-V-V-A-T-L-F-F-A-V-A-F-R-D-P-P-K-I-G-K-D-S-G-K"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-A-T-T-L-R-D-I-L-D-K-L-L-G-R-Q-P-A-S-A-K-T-A-R-E-R-L-Q-L-V-L-A-H-D-R-S-D-L-S-P-E-L-L-D-Q-M-R-R-E-I-F-E-V-V-A-K-Y-V-E-I-D-L-E-E-G-E-V-S-L-E-T-E-D-R-M-T-A-L-V-A-N-L-P-I-K-R-S-Q-A-K-A-V-S-S-Q-E-N-G-A-S-S-Q-E-A-V-S-S-Q-E-S-V-S-T-P-G-A-M-E"} +{"text": "### FUNCTION Involved in the binding and/or turnover of quinones at the Q site of Photosystem II ### SEQUENCE -M-T-A-S-L-A-N-Y-L-S-S-L-V-W-A-A-V-I-V-V-I-P-A-A-V-A-L-V-L-I-S-Q-N-D-Q-M-Y-R-K"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-P-H-P-L-L-P-D-L-E-T-L-A-S-A-T-A-A-G-K-G-Y-K-L-C-C-V-Q-V-F-T-H-L-I-P-M-T-I-Q-V-Q-I-R-R-K-D-G-S-D-V-S-L-D-D-C-A-H-F-S-A-S-M-D-E-A-L-E-A-S-Q-L-F-T-E-A-Y-V-L-E-I-S-S-P-G-I-G-D-Q-L-H-S-D-Q-D-F-L-T-F-R-G-F-P-V-E-I-S-F-R-D-H-D-S-D-L-H-Q-A-G-L-L-H-K-R-S-D-E-H-V-H-I-N-I-K-G-R-I-Q-R-I-P-R-K-A-V-T-C-V-R-L-T-N-P-T-G"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-T-S-L-L-L-F-G-A-G-G-L-F-D-F-D-A-T-L-P-L-M-A-L-Q-V-V-L-L-T-F-I-L-N-A-L-F-F-R-P-V-G-R-V-V-E-E-R-E-V-Y-V-T-T-S-R-A-E-A-K-Q-K-L-A-E-A-E-K-L-E-L-E-L-K-E-Q-L-K-S-A-R-I-A-A-Q-Q-L-I-Q-E-A-E-K-D-S-E-Q-L-Y-R-E-A-L-A-I-A-N-A-D-A-N-A-A-R-E-K-A-R-R-E-I-D-A-Q-R-D-S-A-L-S-Q-L-K-G-D-A-E-K-L-G-D-L-I-V-N-R-L-L-A-A-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-I-S-P-L-F-F-A-S-E-G-G-F-G-L-N-L-D-L-F-D-A-N-I-V-N-L-A-I-V-I-F-G-L-Y-K-F-L-P-P-F-I-G-G-I-L-E-R-R-R-V-A-I-M-A-D-L-Q-D-S-E-D-R-L-L-K-A-T-E-A-L-A-A-A-K-K-D-L-A-A-A-H-Q-K-A-E-Q-I-R-E-D-C-K-L-R-A-E-A-I-R-L-D-S-E-K-R-T-V-E-E-M-A-R-V-K-Q-G-A-T-A-D-L-N-A-E-A-S-R-A-S-A-Q-L-R-R-E-A-A-R-M-A-I-E-N-A-L-S-A-L-P-G-K-L-N-T-E-A-Q-S-K-L-V-S-Q-S-I-K-N-L-G-E-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-P-L-L-N-T-I-T-T-P-Y-A-E-A-F-L-Q-V-A-E-S-R-K-E-V-D-Q-V-V-D-Q-A-K-A-V-L-A-L-W-N-D-C-P-E-L-S-G-A-M-A-S-P-V-L-E-V-E-A-K-K-A-A-L-Q-K-L-F-A-N-Q-V-T-P-S-F-L-N-L-L-K-L-L-A-D-R-Q-R-I-G-V-L-D-A-V-L-E-R-L-I-E-L-Y-R-E-Q-R-N-I-A-L-A-T-V-T-S-A-A-E-L-S-E-Q-Q-Q-A-A-L-Q-K-K-V-Q-A-V-A-N-T-D-K-L-E-I-N-L-K-I-D-P-D-L-I-G-G-F-V-V-N-V-G-S-K-V-I-D-A-S-V-A-G-Q-V-R-R-L-G-L-A-L-A-K-V-S"} +{"text": "### FUNCTION Probably a ribosomal protein or a ribosome-associated protein ### SEQUENCE -M-R-G-G-S-A-A-L-A-T-A-T-I-D-A-D-G-V-P-S-G-Y-T-P-K-A-D-E-G-R-F-L-L-K-I-L-W-L-P-D-N-V-A-L-A-V-D-Q-I-V-G-G-G-P-S-P-L-T-A-Y-F-F-W-P-R-E-D-A-W-E-T-L-K-G-E-L-E-G-K-S-W-I-T-D-N-E-R-V-E-V-L-N-K-A-T-E-V-I-N-Y-W-Q-E-E-G-K-G-K-N-L-E-E-A-K-L-K-F-P-D-V-T-F-C-G-T-A"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-I-T-S-G-V-E-P-K-D-L-A-K-R-G-E-S-L-I-R-Q-S-S-N-R-Y-L-T-T-V-R-I-A-F-R-A-K-Q-R-R-F-D-D-F-D-G-L-L-E-E-S-S-V-K-P-V-Q-R-A-I-V-E-L-S-D-E-Q-D-Q-P-D-L-L-P-G"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-A-E-K-P-T-A-K-P-K-A-A-E-A-K-D-Q-S-D-S-Y-A-I-V-E-A-S-G-Q-Q-F-L-L-Q-P-N-R-Y-Y-D-L-D-R-L-Q-A-A-V-D-D-T-V-T-L-E-K-V-L-L-I-K-D-G-K-N-D-A-T-V-G-Q-P-Y-V-K-G-A-S-V-E-L-K-V-M-D-H-R-R-G-P-K-I-I-V-Y-K-M-R-P-K-K-K-T-R-R-K-N-G-H-R-Q-E-L-T-R-V-M-V-Q-S-I-S-I-D-G-K-A-L-S"} +{"text": "### FUNCTION Component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria ### SEQUENCE -M-S-P-R-K-T-Y-I-L-K-L-Y-V-A-G-N-T-P-N-S-M-R-A-L-K-T-L-R-D-I-L-E-N-E-F-R-G-V-Y-A-L-K-V-I-D-V-L-K-N-P-Q-L-A-E-A-D-K-I-L-A-T-P-T-L-A-K-I-L-P-P-P-V-R-R-I-I-G-D-L-S-D-R-E-R-V-L-I-G-L-D-L-L-Y-D-E-I-S-E-E-M-L-G-S-A-E-L-D-T-L-A-D-D-D-I-A-S-P-D-S"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-L-T-S-E-Q-I-M-G-L-L-P-H-R-Y-P-F-A-L-V-D-R-V-V-L-H-E-P-G-Q-R-A-V-A-I-K-N-V-T-L-N-E-P-Q-F-Q-G-H-F-P-G-R-P-L-M-P-G-V-L-I-V-E-A-M-A-Q-V-G-G-L-I-V-A-Q-M-P-D-L-P-K-G-L-F-V-F-A-G-I-D-A-V-R-F-R-R-P-V-V-P-G-D-Q-L-T-I-S-C-E-L-L-S-L-K-R-Q-R-F-G-K-V-R-G-E-A-R-V-E-G-Q-L-V-C-S-G-E-L-M-F-S-L-V-D"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-V-L-P-A-S-M-R-L-R-G-S-R-C-F-E-H-L-Q-K-W-G-Y-R-F-Y-G-T-S-M-V-L-R-V-I-E-A-N-P-Q-L-L-K-A-P-H-R-H-H-N-S-T-A-C-R-C-A-V-V-I-S-S-K-V-S-K-R-A-V-I-R-N-R-L-R-R-L-L-H-D-H-L-R-S-R-L-E-V-A-P-E-H-C-N-H-W-V-L-I-S-L-K-P-V-A-S-A-I-E-A-S-P-L-L-E-E-C-D-R-L-L-N-Q-A-G-L-L-S"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-R-K-F-F-E-S-W-P-M-A-A-V-L-W-V-W-L-T-A-G-I-I-V-E-F-N-R-F-Y-P-D-L-L-F-H-P-M-G-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-T-A-D-S-K-D-T-S-M-S-E-D-N-T-E-T-A-T-A-I-E-N-S-S-A-M-V-T-D-V-T-S-K-S-A-P-N-V-R-L-S-P-D-A-L-I-K-E-F-E-A-S-Q-Q-K-S-D-L-N-D-I-Y-V-G-D-T-V-R-V-G-V-R-I-S-E-G-N-K-E-R-I-Q-P-Y-E-G-V-V-I-A-K-R-H-G-G-I-H-E-T-I-T-V-R-R-I-F-Q-G-I-G-V-E-R-V-F-M-L-H-S-P-Q-V-A-S-I-K-V-E-R-R-G-K-V-R-R-A-K-L-F-Y-L-R-E-R-V-G-K-A-T-R-V-K-Q-R-F-D-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-N-Q-E-L-K-D-N-M-H-K-S-V-E-A-T-Q-R-N-F-A-T-I-R-T-G-R-A-N-P-S-L-L-D-R-I-N-V-E-Y-Y-G-T-E-T-P-L-K-S-L-A-T-I-S-T-P-D-S-Q-T-I-A-I-Q-P-F-D-N-G-S-M-G-L-I-E-K-A-I-A-T-S-D-L-G-L-T-P-N-N-D-G-K-I-I-R-I-N-V-P-P-L-T-E-E-R-R-K-E-F-C-K-L-A-A-R-Y-A-E-E-G-K-V-A-L-R-N-I-R-R-D-A-I-D-K-V-K-K-L-E-K-D-A-E-L-S-K-D-Q-S-H-D-E-Q-D-G-I-Q-K-L-T-D-T-F-I-T-E-I-E-K-Y-L-A-E-K-E-A-D-I-L-K-V"} +{"text": "### FUNCTION RuBisCO catalyzes two reactions the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process Both reactions occur simultaneously and in competition at the same active site Although the small subunit is not catalytic it is essential for maximal activity ### SEQUENCE -M-P-F-Q-S-T-V-G-D-Y-Q-T-V-A-T-L-E-T-F-G-F-L-P-P-M-T-Q-D-E-I-Y-D-Q-I-A-Y-I-I-A-Q-G-W-S-P-V-I-E-H-V-H-P-S-G-S-M-Q-T-Y-W-S-Y-W-K-L-P-F-F-G-E-K-D-L-N-M-V-V-S-E-L-E-A-C-H-R-A-Y-P-D-H-H-V-R-M-V-G-Y-D-A-Y-T-Q-S-Q-G-T-A-F-V-V-F-E-G-R"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-L-A-S-A-S-P-A-R-R-R-L-L-Q-Q-A-A-I-P-H-Q-V-M-V-S-G-V-D-E-E-T-I-H-H-F-D-P-V-R-L-V-Q-H-L-A-E-A-K-A-G-V-V-H-Q-Q-I-K-A-A-L-P-V-L-G-C-D-S-V-L-E-F-D-G-T-V-F-G-K-P-A-T-A-V-E-A-S-S-R-W-Q-R-M-A-G-A-W-G-F-L-H-T-G-H-C-L-L-S-V-N-G-E-R-L-S-E-T-V-T-T-R-V-L-F-A-A-L-S-D-S-E-I-E-A-Y-V-A-T-G-E-P-L-L-C-A-G-G-F-A-L-E-G-Q-G-G-L-M-V-E-R-L-E-G-C-F-S-N-V-I-G-L-S-L-P-L-L-R-R-W-L-L-V-I-N-E"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-S-A-D-L-Q-E-T-P-K-A-G-D-A-S-L-E-R-L-E-Q-S-V-L-G-F-R-R-L-S-N-Q-L-L-A-V-I-V-T-I-G-G-L-G-F-T-L-T-C-L-S-S-Y-L-G-R-D-L-L-P-I-G-S-P-S-T-L-L-F-V-P-Q-G-L-V-M-G-L-Y-G-I-A-G-L-L-L-A-S-Y-L-W-A-M-I-N-I-N-L-G-A-G-S-N-N-F-D-K-A-S-G-M-V-K-I-C-R-R-G-Y-F-K-L-I-S-A-E-F-P-L-K-D-V-K-A-V-K-V-E-V-R-D-G-F-N-P-L-R-R-L-S-L-R-V-Q-G-R-R-D-I-T-L-T-R-V-G-Q-P-L-P-L-A-Q-L-E-Q-D-G-A-E-L-A-R-F-L-D-V-N-L-E-G-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-I-E-P-L-L-C-G-I-V-L-G-L-I-P-V-T-L-L-G-L-F-V-D-A-W-N-Q-Y-R-R-D-T-V-L-G-D-W"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-I-D-Q-F-E-R-L-P-G-I-G-P-R-T-A-Q-R-L-A-L-H-L-L-R-Q-P-E-D-Q-I-R-A-F-A-D-A-L-L-A-A-R-S-Q-V-G-Q-C-Q-T-C-F-H-L-S-A-E-P-L-C-D-I-C-R-D-G-K-R-C-D-Q-L-L-C-V-V-A-D-S-R-D-L-L-A-L-E-R-T-R-E-Y-K-G-R-Y-H-V-L-G-G-L-I-S-P-M-D-G-I-G-P-D-M-L-Q-I-P-S-L-I-Q-R-V-D-R-D-G-I-S-E-V-I-L-A-L-T-P-S-V-E-G-D-T-T-S-L-Y-L-A-R-L-L-K-P-F-T-Q-V-S-R-I-A-Y-G-L-P-V-G-S-E-L-E-Y-A-D-E-V-T-L-T-R-A-L-E-G-R-R-A-M-Q"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-R-H-L-I-Q-D-V-P-D-F-P-K-P-G-I-L-F-R-D-I-S-P-L-L-R-D-P-D-G-W-D-E-V-M-R-Q-L-G-D-L-C-T-E-L-K-P-D-L-I-V-G-I-E-S-R-G-F-I-V-G-T-A-L-A-T-N-R-K-I-G-F-V-P-V-R-K-P-G-K-L-P-G-D-V-L-G-I-D-Y-S-L-E-Y-G-S-D-R-L-E-I-H-A-D-A-L-Q-G-H-P-R-V-L-L-V-D-D-L-L-A-T-G-G-T-A-R-A-T-V-E-L-I-E-K-A-G-G-D-L-V-G-C-G-F-V-I-E-L-A-A-L-G-G-R-Q-Q-L-P-V-E-I-P-V-K-S-L-I-I-Y-S"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-I-P-I-V-I-E-E-S-G-R-G-E-R-A-F-D-I-Y-S-R-L-L-R-E-R-I-I-F-L-G-E-P-V-T-S-D-S-A-N-R-I-V-A-Q-M-L-F-L-E-A-E-D-P-E-K-D-I-Y-L-Y-I-N-S-P-G-G-S-V-Y-D-G-L-G-I-F-D-T-M-Q-H-V-K-P-D-V-Q-T-V-C-V-G-L-A-A-S-M-G-A-F-L-L-C-A-G-A-M-G-K-R-S-S-L-Q-H-S-R-I-M-I-H-Q-P-L-G-G-A-R-G-Q-A-S-D-I-R-I-Q-A-D-E-I-L-F-L-K-D-R-L-N-R-V-L-A-D-R-T-G-Q-P-L-E-R-I-Q-E-D-T-D-R-D-F-F-M-S-P-A-E-A-V-G-Y-G-L-V-D-S-V-I-D-K-R-P-V-H-S-V-N"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-L-F-T-L-A-W-A-S-L-A-A-V-F-S-F-S-I-A-M-V-V-W-G-R-N-G-D-G-T-L-N-F"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-R-N-C-A-F-R-I-I-A-V-G-K-V-R-K-G-W-I-Q-D-G-L-A-M-Y-Q-K-R-L-P-G-L-I-I-T-E-V-R-D-A-S-M-P-R-E-A-E-A-I-R-A-A-L-N-S-N-E-V-L-V-P-L-S-E-E-G-E-A-L-T-S-V-S-F-A-K-R-L-E-K-Y-G-S-Q-R-L-A-F-V-I-G-G-A-D-G-L-S-A-E-L-K-N-S-T-Q-W-Q-L-S-L-S-A-M-T-L-P-H-E-L-A-R-L-L-L-V-E-Q-L-Y-R-A-Q-T-I-T-Q-G-G-K-Y-H-R-S"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-T-A-T-K-P-S-P-K-S-M-L-S-L-D-L-G-K-R-R-I-G-L-A-G-C-D-P-L-G-I-T-V-S-P-L-P-P-L-Q-R-K-S-F-E-R-D-L-K-V-L-Q-W-H-C-T-S-R-K-V-E-G-L-V-V-G-L-P-L-D-A-K-G-L-P-T-D-Q-A-R-H-Y-E-R-Y-G-Q-R-L-A-R-A-L-K-L-P-L-A-L-V-N-E-H-S-S-S-W-A-A-A-E-R-Y-N-L-Q-G-D-R-S-G-Q-L-D-S-A-A-A-A-L-L-L-E-Q-W-L-R-E-G-P-E-L-K-P-V-H-V-A-A-H-P-V-S-Q-V-N-S-D-S-G-S"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-V-K-E-I-L-R-M-G-N-P-Q-L-R-K-V-S-N-V-V-D-D-A-S-D-E-L-I-I-S-L-I-K-D-L-Q-D-T-V-K-A-H-Q-G-A-G-L-A-A-P-Q-I-G-V-P-L-R-V-V-L-F-G-G-G-G-P-N-P-R-Y-P-E-A-P-S-I-P-Q-T-L-L-I-N-P-V-L-T-P-I-G-S-D-L-E-D-G-W-E-G-C-L-S-V-P-G-L-R-G-K-V-S-R-W-S-R-I-H-Y-R-A-L-N-E-D-G-F-E-V-E-H-C-L-E-G-F-P-A-R-V-I-Q-H-E-C-D-H-L-D-G-V-L-F-P-D-R-L-V-D-S-A-S-F-G-F-T-G-E-L-E-T-A-G-I-I-E-K-L-S-S-A-E-Q-K-A-S-Q-Q-S-R-A-D"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-P-I-G-T-P-S-V-P-Y-R-L-P-G-S-Q-M-E-R-W-V-D-I-Y-T-R-L-G-V-E-R-I-L-F-L-G-Q-E-V-S-D-G-V-A-N-S-L-V-A-Q-M-L-Y-L-D-S-E-D-S-T-K-P-I-Y-L-Y-I-N-S-P-G-G-S-V-T-A-G-L-A-I-Y-D-T-M-K-Y-V-K-S-D-V-V-T-I-C-V-G-L-A-A-S-M-G-A-F-L-L-T-A-G-T-K-G-K-R-L-A-L-P-H-S-R-I-M-I-H-Q-P-L-G-G-T-N-Q-R-Q-A-S-D-I-E-I-E-A-R-E-I-L-R-I-K-D-M-L-N-H-S-M-A-E-L-T-G-Q-S-F-E-K-I-E-K-D-T-D-R-D-Y-F-L-S-A-A-E-A-K-D-Y-G-L-I-D-R-V-I-A-H-P-N-E-A"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-L-I-S-R-L-R-A-V-V-A-G-D-D-Y-L-D-S-D-Y-D-D-L-D-Y-D-T-D-D-H-M-D-A-D-H-R-S-D-H-A-S-G-G-A-L-A-T-P-S-D-S-S-P-F-D-L-G-G-G-F-S-G-S-N-V-I-G-M-P-G-V-G-S-T-S-A-E-V-N-L-M-E-P-R-S-F-D-E-M-P-R-A-I-Q-A-L-R-E-R-K-T-V-I-L-N-L-T-M-M-E-P-D-Q-A-Q-R-A-V-D-F-V-A-G-G-T-F-A-I-D-G-H-Q-E-R-V-G-E-S-I-F-L-F-A-P-S-C-V-T-V-S-N-T-S-Y-D-E-A-S-A-P-S-M-V-S-Q-D-H-D-S-V-P-S-S-S-Q-Q-T-G-A-A-P-V-P-A-W-E-A-T-S-A-G-G-L"} +{"text": "### FUNCTION Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase ### SEQUENCE -M-A-I-S-K-G-D-K-V-R-I-R-R-E-E-S-Y-W-H-N-E-V-G-T-V-A-S-V-D-T-T-G-K-Y-G-V-L-V-R-F-E-K-T-N-Y-F-G-M-Q-G-T-D-N-G-N-L-T-N-S-F-A-E-S-E-L-D-R-A"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-G-G-N-K-K-A-T-A-A-A-R-A-A-A-N-R-L-L-A-D-N-R-L-A-R-H-Q-Y-E-I-L-D-T-L-E-T-G-I-E-L-V-G-T-E-V-K-S-I-R-A-G-Q-A-N-L-R-D-G-F-C-L-I-R-K-G-E-L-Q-L-H-N-V-H-I-S-P-H-S-H-A-G-S-Y-F-N-H-D-P-L-R-T-R-K-L-L-A-H-R-R-E-I-D-K-L-R-G-Q-L-D-R-K-G-L-T-L-I-P-L-N-L-H-L-K-G-S-W-I-K-L-T-I-G-L-G-K-G-R-K-L-H-D-K-R-Q-D-E-K-R-K-Q-A-D-R-E-V-K-S-A-L-A-R-Y"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-A-N-P-T-Q-P-L-P-N-Q-W-N-E-M-W-L-V-A-F-G-A-V-P-G-A-L-V-R-W-Q-V-Q-N-D-L-L-V-N-V-I-G-A-A-I-L-G-L-V-V-G-L-P-F-R-P-S-R-Q-L-L-L-G-V-G-F-C-G-S-L-T-T-F-S-S-W-M-V-E-C-S-T-L-I-S-Q-G-A-W-L-S-A-L-G-L-I-G-L-T-M-G-L-G-L-G-V-A-A-L-G-F-L-I-G-W-Q-F-R-P-S-G-L-G-R"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-S-D-L-A-L-P-A-W-Q-A-S-L-V-A-I-G-A-V-P-G-A-W-L-R-L-R-V-V-N-H-L-E-P-M-V-P-R-K-H-W-G-T-F-A-V-N-M-V-A-A-F-A-L-G-L-V-L-A-L-Q-A-K-C-A-P-E-S-G-A-S-P-L-I-L-L-I-G-V-G-F-F-G-S-L-S-T-F-S-T-F-A-V-E-V-L-N-T-L-R-E-H-R-W-S-E-A-L-V-L-A-V-G-S-I-L-G-G-L-L-A-V-A-A-G-V-G-L-A-N-G"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-M-A-T-Y-E-G-C-Y-T-D-A-Q-A-L-R-I-A-V-V-V-A-R-F-N-D-L-V-T-G-K-L-L-S-G-C-L-D-C-L-A-R-H-G-V-D-T-S-S-N-S-E-Q-L-D-V-A-W-V-P-G-A-F-E-L-P-I-V-T-Q-T-L-A-L-S-G-Q-Y-Q-V-V-I-T-L-G-A-V-I-R-G-D-T-P-H-F-D-V-V-V-A-E-A-S-K-G-I-A-S-V-S-R-E-T-G-V-P-V-I-F-G-V-L-T-T-D-T-M-Q-Q-A-L-E-R-A-G-I-K-S-N-L-G-W-S-Y-G-L-Q-A-L-E-M-G-S-L-M-A-V-L-R-S-A-T-S-A-S"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-N-V-A-R-K-R-R-N-K-I-L-R-L-A-R-G-F-Q-G-S-N-G-S-L-F-R-T-A-N-Q-R-V-M-K-A-L-C-N-A-Y-R-D-R-R-R-R-K-R-D-F-R-R-L-W-I-A-R-I-N-A-A-A-R-I-N-G-V-S-Y-S-R-L-I-G-G-L-K-K-A-D-V-R-I-N-R-K-M-L-A-Q-L-A-V-M-D-P-K-S-F-T-S-V-V-T-S-A-K-S"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-S-N-D-F-R-T-G-T-S-I-E-L-D-G-S-V-W-R-V-V-E-F-L-H-V-K-P-G-K-G-S-A-F-V-R-T-K-L-K-A-V-Q-S-G-N-V-V-E-K-T-F-R-A-G-E-M-L-P-Q-A-L-L-E-K-S-T-L-Q-H-T-Y-M-E-S-G-D-Y-V-F-M-D-M-S-S-Y-E-E-T-R-L-T-A-Q-Q-I-G-D-S-R-K-Y-L-K-E-G-M-E-V-N-V-V-S-W-N-G-N-P-L-E-V-E-L-P-N-S-V-V-L-E-I-T-E-T-D-P-G-V-K-G-D-T-A-T-G-G-T-K-P-A-I-L-E-T-G-A-Q-V-M-V-P-L-F-L-S-V-G-E-K-I-K-V-D-T-R-N-D-S-Y-L-G-R-E-N"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-G-F-G-L-P-N-F-G-Q-L-T-E-A-F-R-K-A-Q-Q-I-Q-Q-N-A-Q-K-L-Q-E-E-L-D-A-M-E-I-E-G-S-S-P-D-G-R-A-S-I-W-L-S-G-N-Q-Q-P-L-R-V-R-I-E-P-S-L-L-A-E-G-Q-D-A-S-E-T-A-I-L-A-A-L-Q-S-A-Y-E-H-S-T-T-T-M-K-E-Q-M-E-E-L-T-G-G-L-N-L-N-L-P-G-M-S-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-K-R-V-K-V-V-L-K-E-D-I-L-S-L-G-K-D-G-D-V-V-E-V-A-P-G-Y-A-R-N-F-L-L-S-Q-Q-K-A-L-A-V-T-P-S-V-L-K-Q-V-E-Y-R-L-A-K-K-A-E-L-E-A-A-K-K-Q-E-A-I-D-F-E-T-A-L-K-T-I-G-R-F-S-I-K-K-Q-T-G-E-D-G-V-L-F-G-T-V-T-N-G-D-V-S-E-A-I-Q-L-A-T-Q-K-E-I-D-R-R-N-I-I-V-P-E-I-H-E-T-G-K-Y-K-V-Q-V-K-L-H-S-E-V-T-A-E-I-N-L-E-V-I-G-N"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-I-F-D-F-P-K-K-F-R-F-A-D-S-H-E-Y-A-C-P-E-G-D-L-V-R-I-G-I-S-A-F-A-V-D-Q-L-G-D-I-V-F-V-D-L-P-G-I-G-T-L-L-E-Q-G-I-S-F-G-S-V-E-S-V-K-A-V-E-D-M-N-A-P-I-G-G-E-V-L-Q-I-N-E-S-V-L-N-S-P-E-E-L-Q-N-D-P-H-G-E-G-W-L-L-L-V-K-P-S-D-A-S-Q-L-D-K-L-M-S-S-E-I-Y-S-E-K-V-S-S-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-S-R-V-K-R-G-N-V-A-R-K-R-R-N-K-I-L-R-L-A-K-G-F-Q-G-S-N-G-S-L-F-R-T-A-N-Q-R-V-M-K-A-L-C-N-A-Y-R-D-R-K-R-R-K-R-D-F-R-R-L-W-I-A-R-I-N-A-A-A-R-M-N-G-M-S-Y-S-K-L-I-G-N-L-K-K-A-D-I-R-I-N-R-K-M-L-A-Q-I-A-I-L-D-P-T-N-F-Q-K-V-V-A-D-V-K-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-V-S-I-E-G-R-F-T-E-A-S-S-L-K-I-G-I-V-A-A-R-F-N-D-L-I-T-S-K-L-L-S-G-C-I-D-C-L-T-R-H-G-I-D-T-S-E-S-S-S-Q-L-D-I-A-W-V-P-G-S-F-E-L-P-L-V-S-Q-T-M-A-K-S-G-R-Y-Q-V-L-I-T-L-G-A-V-I-R-G-D-T-P-H-F-E-V-V-I-N-E-S-S-K-G-I-A-S-V-S-R-E-T-G-V-P-I-I-F-G-V-L-T-T-D-T-M-Q-Q-A-L-E-R-A-G-V-K-N-N-L-G-W-N-Y-A-L-Q-A-I-E-M-G-S-L-M-K-A-L-K"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-F-D-G-L-S-T-Y-K-S-F-F-L-V-A-F-G-A-V-P-G-A-I-C-R-M-K-I-S-D-N-L-F-R-N-K-H-N-L-W-G-I-L-L-V-N-S-S-A-C-L-L-L-G-F-F-L-A-K-Q-N-Y-I-H-Y-I-N-N-D-Q-P-L-Y-L-L-L-C-V-G-F-L-G-S-F-S-T-F-S-S-L-I-L-E-I-Y-Y-L-F-V-D-Q-Q-W-M-E-L-F-L-F-T-F-T-S-I-G-L-G-I-I-F-I-S-L-G-S-H-L-F-N-A"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-H-S-K-L-N-I-Q-S-K-Q-L-Y-K-I-F-L-L-I-V-G-S-I-L-G-A-I-L-R-W-K-L-N-N-Y-F-W-V-N-I-S-G-A-A-L-L-G-L-I-V-G-L-R-A-G-S-R-I-Q-F-F-L-V-I-G-F-C-G-S-F-T-T-F-S-G-W-I-L-D-V-F-D-L-F-R-T-G-F-F-W-K-A-A-G-L-I-C-S-N-L-L-G-G-F-T-A-L-S-V-T-F-W-I-G-R-K-I-R-H-L-F-I-P-Q"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-K-A-R-N-N-K-K-S-K-L-S-K-A-K-S-N-R-R-L-A-E-N-R-Y-A-R-H-Q-Y-E-I-L-E-D-I-E-A-G-I-E-L-L-G-T-E-V-K-S-I-R-A-G-N-V-N-L-R-D-G-F-C-L-I-R-E-G-S-L-L-L-H-N-V-H-I-S-P-F-N-N-A-G-S-F-F-N-H-E-P-L-R-V-R-K-L-L-A-H-R-K-E-I-N-K-L-E-T-Q-V-N-R-K-G-L-T-L-V-P-L-N-I-F-L-K-G-S-W-I-K-I-T-I-G-L-G-K-G-R-K-L-H-D-K-R-E-N-E-K-R-K-Q-S-E-R-E-V-K-S-A-L-A-R-Y"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-Q-E-A-I-L-E-K-V-R-S-I-V-A-E-Q-L-S-V-E-A-S-E-I-K-P-D-S-N-F-Q-N-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-A-F-D-I-E-I-P-D-E-A-A-E-G-I-T-T-V-G-D-A-V-K-Y-I-E-D-K-Q-S"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-C-K-K-I-I-W-L-T-I-G-K-I-V-A-P-Q-G-L-S-G-K-V-R-I-N-P-S-S-D-F-P-E-R-F-I-K-S-G-D-R-W-L-Q-Y-D-N-E-E-P-Q-K-I-Q-L-N-S-G-R-Q-I-P-G-K-S-I-Y-V-V-E-F-Q-G-I-D-D-R-E-K-A-K-A-L-V-G-K-K-L-L-I-D-S-S-H-R-P-T-L-A-P-G-E-F-H-L-L-D-L-L-G-L-K-V-R-L-K-N-D-H-R-E-I-G-E-V-T-N-L-T-S-A-G-N-D-L-L-E-V-R-L-L-S-G-K-K-V-L-V-P-F-V-K-E-I-V-P-E-I-K-L-Q-E-G-W-L-M-V-C-P-P-P-G-L-F-D-L"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-P-L-L-L-S-G-R-K-F-R-H-D-L-E-A-S-G-C-L-A-I-N-V-P-L-E-G-G-A-E-T-R-L-L-R-R-L-K-A-A-G-Y-K-T-Q-I-T-S-V-R-G-L-G-D-P-E-A-F-L-L-K-L-H-G-I-R-P-P-H-L-G-H-Q-N-V-G-R-N-G-A-L-G-E-V-Q-Q-V-I-P-Q-V-N-E-L-L-A-G-E-K-S-V-V-L-W-L-L-E-G-Q-V-L-S-R-S-E-I-L-S-L-C-D-L-C-D-K-E-P-R-L-K-I-V-I-E-M-G-G-A-R-A-L-R-W-Q-S-M-R-S-F-I-Q"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-E-M-F-K-E-R-L-A-D-V-I-R-R-P-L-I-T-E-K-A-T-K-G-L-D-I-N-Q-Y-T-F-E-V-D-H-R-A-A-K-P-D-I-K-A-A-V-E-K-L-F-D-V-K-V-I-G-I-S-T-M-N-P-P-R-R-S-R-R-V-G-R-F-S-G-K-R-A-Q-V-K-K-A-I-V-R-L-A-E-G-N-S-I-Q-L-F-P-D-S-E-S"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-I-A-D-S-L-I-K-K-V-E-K-Q-N-S-D-D-D-K-S-V-I-K-T-W-S-R-A-S-T-I-L-P-M-M-I-G-H-T-I-A-V-H-N-G-K-T-H-V-P-V-F-I-T-E-Q-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-M-K-D-K-K-G-G-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-D-L-P-L-A-Q-A-H-G-R-F-I-R-G-S-A-S-K-V-R-R-V-L-D-Q-I-R-G-R-T-Y-R-D-A-L-I-M-L-E-F-M-P-Y-R-S-T-G-P-I-T-K-V-L-R-S-A-V-A-N-A-E-N-N-L-G-M-D-P-S-S-L-I-I-K-T-A-S-A-D-M-G-P-S-M-K-R-Y-R-P-R-A-Q-G-R-A-F-A-I-K-K-Q-T-C-H-I-S-I-A-V-A-P-S-N-Q-S-T-T-T-E-A-S-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-L-K-E-R-L-G-T-V-V-S-D-K-M-D-K-T-V-V-V-A-V-V-N-R-F-P-H-S-I-Y-Q-K-T-V-S-R-T-T-R-Y-K-A-H-D-E-E-N-N-C-K-V-G-D-R-V-R-I-T-E-T-R-P-L-S-A-T-K-R-W-S-V-A-E-V-L-R-T-T-K-Q-E-K-E-A-V-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-Y-L-T-V-A-D-N-S-G-A-K-R-L-Q-C-I-R-V-L-G-S-N-R-R-Y-A-H-V-G-D-V-I-V-A-A-V-K-D-A-V-P-N-M-G-V-K-K-S-D-V-V-K-A-V-V-V-R-T-K-A-T-L-R-R-E-T-G-N-S-I-R-F-D-D-N-A-A-V-L-I-N-E-D-K-N-P-R-G-T-R-V-F-G-P-V-A-R-E-L-R-E-R-N-Y-T-K-I-V-S-L-A-P-E-V-I"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-F-N-L-N-Q-T-K-K-A-S-L-P-I-K-M-R-I-R-K-G-D-T-V-Q-V-I-N-G-K-E-K-G-K-T-G-E-V-L-K-T-L-P-I-E-N-R-V-I-V-Q-G-I-N-L-R-T-R-H-V-K-P-T-Q-E-G-E-S-G-R-I-V-T-E-E-A-S-L-H-A-S-N-V-M-V-Y-S-T-K-Q-K-T-A-S-R-V-E-V-F-I-D-K-D-G-S-K-K-R-R-L-K-K-T-G-E-L-I-D"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-L-K-N-R-Y-R-E-T-I-R-P-K-L-L-K-D-L-G-F-S-N-L-H-Q-V-P-K-V-V-K-I-N-V-N-R-G-L-G-E-A-A-Q-N-S-K-A-L-E-A-S-L-S-E-V-S-T-I-T-G-Q-K-A-L-V-T-R-A-K-K-A-I-A-G-F-K-I-R-Q-G-M-P-I-G-C-A-V-T-L-R-G-E-R-M-Y-A-F-L-E-R-L-I-N-L-A-L-P-R-I-R-D-F-R-G-V-S-P-K-S-F-D-G-R-G-N-F-T-L-G-V-K-E-Q-L-I-F-P-E-I-S-F-D-K-I-D-A-I-R-G-M-D-I-T-I-V-T-S-A-R-T-D-E-E-G-R-A-L-L-K-E-M-G-M-P-F-R-S-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-A-N-H-D-P-I-S-D-M-L-T-R-I-R-N-A-S-Q-K-R-H-E-N-T-R-I-P-A-S-R-M-S-R-S-I-A-K-V-L-Q-N-E-G-F-I-S-Q-V-S-E-E-G-E-G-V-K-T-Q-L-V-L-E-L-K-Y-S-G-K-H-R-H-P-T-I-R-S-M-K-R-V-S-K-P-G-L-R-I-Y-K-N-N-R-G-L-P-K-V-L-G-G-L-G-V-A-I-I-S-T-S-K-G-V-M-S-D-R-D-A-R-K-Q-G-V-G-G-E-V-L-C-Y-V-Y"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-P-I-P-V-P-E-K-V-A-V-T-L-D-G-L-L-V-T-V-K-G-P-K-G-E-L-T-R-T-L-P-E-G-V-T-I-D-Q-T-D-G-L-I-I-V-S-A-D-S-E-K-R-K-S-R-E-R-H-G-L-S-R-T-L-V-A-N-M-I-E-G-V-N-N-G-Y-S-K-Q-L-E-I-V-G-V-G-S-R-A-Q-V-K-G-K-T-L-V-V-S-A-G-Y-S-H-P-V-E-V-I-P-P-E-G-I-T-F-K-V-E-N-N-T-N-V-L-V-S-G-I-D-K-E-L-V-G-N-E-A-A-K-I-R-A-I-R-P-P-E-P-Y-K-G-K-G-I-K-Y-L-G-E-R-I-L-R-K-A-G-K-S-G-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-T-L-S-R-K-Q-K-T-Q-K-R-H-K-R-L-R-R-N-L-S-G-T-D-Q-R-P-R-L-A-V-F-R-S-N-N-H-I-Y-A-Q-V-I-D-D-V-A-Q-N-T-L-C-A-A-S-T-L-E-K-E-F-L-S-N-S-K-V-N-A-S-T-C-A-A-S-T-A-V-G-E-M-L-A-K-R-A-L-G-K-G-I-K-Q-V-V-F-D-R-G-G-S-L-Y-H-G-R-V-K-A-L-A-E-A-A-R-Q-A-G-L-T-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-S-I-S-L-D-S-L-K-P-N-K-G-A-R-K-R-K-T-R-K-G-R-G-I-A-A-G-Q-G-A-S-C-G-F-G-M-R-G-Q-K-S-R-S-G-R-P-T-R-P-G-F-E-G-G-Q-M-P-L-Y-R-R-V-P-K-L-K-H-F-P-L-V-N-S-K-S-F-T-L-I-N-V-A-S-L-N-S-L-K-E-G-S-T-V-N-L-D-S-L-V-K-T-G-I-V-T-S-P-K-Y-P-L-K-V-L-G-N-G-N-L-K-V-K-L-V-V-Q-A-A-A-F-T-A-S-A-K-T-K-I-E-G-A-G-G-S-C-E-V-F-E"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-D-L-P-R-D-K-R-V-E-I-A-L-T-Y-I-Y-G-I-G-L-T-R-A-Q-N-I-L-A-K-T-G-V-N-P-D-I-R-V-K-D-L-E-D-G-D-V-Q-K-L-R-A-A-T-E-S-F-T-I-E-G-D-L-R-R-Q-E-G-M-A-L-K-R-L-Q-D-I-G-C-L-R-G-R-R-H-R-M-S-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-R-G-S-R-K-T-V-A-G-R-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-T-P-A-K-K-T-G-S-K-K-S-K-R-N-V-P-N-G-V-V-H-I-Q-S-T-F-N-N-T-I-V-S-I-T-D-T-N-G-E-V-I-S-W-S-S-A-G-A-S-G-F-K-G-A-R-K-G-T-P-F-A-A-Q-T-A-A-E-A-A-A-R-R-A-L-D-Q-G-M-R-Q-I-E-V-L-V-R-G-P-G-S-G-R-E-T-A-I-R-A-L-Q-V-A-G-L-E-I-T-L-I-R-D-V-T-P-L-P-H-N-G-C-R-R-A-K-R-R-R-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-N-K-T-I-T-P-S-I-D-S-I-N-R-Q-W-Y-L-V-D-A-E-N-Q-T-L-G-R-L-A-T-E-V-A-S-V-L-R-G-K-N-K-P-S-F-T-P-H-L-D-T-G-D-F-V-I-I-V-N-A-E-K-I-K-V-T-G-K-K-G-M-Q-K-L-Y-R-R-H-S-G-R-P-G-G-M-K-V-E-T-F-N-S-L-Q-E-R-I-P-E-R-I-V-E-K-A-I-K-G-M-L-P-H-N-A-L-G-R-Q-L-F-R-K-L-K-V-Y-K-G-S-E-H-P-H-S-A-Q-N-P-Q-V-L-S-I-T-T-N-E-L-V-K"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-P-K-K-D-I-H-P-N-W-Y-P-D-A-K-V-I-C-N-G-E-V-V-M-T-T-G-S-T-Q-P-E-I-H-V-D-V-W-S-G-N-H-P-F-F-T-G-T-Q-K-I-L-D-T-E-G-R-V-D-R-F-M-R-K-Y-G-M-A-N-P-D-E-D-S-T-K-N-T-K-S-S-K-K-E-T-S-E-D-S-S-S-K-G-S"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-Q-Q-L-I-R-T-E-R-Q-R-L-T-R-K-T-K-S-P-A-L-R-S-C-P-E-R-R-G-V-C-T-R-V-Y-T-S-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-L-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-I-R-G-T-L-D-T-A-G-V-K-D-R-R-Q-A-R-S-K-Y-G-A-K-A-P-K-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-N-A-A-E-K-R-P-V-L-P-D-P-Q-F-N-N-R-L-A-T-M-M-V-A-R-L-M-K-H-G-K-K-S-T-A-Q-K-I-L-S-Q-A-F-G-L-I-N-E-R-T-G-G-D-P-I-E-L-F-E-T-A-I-K-N-A-T-P-L-V-E-V-R-A-R-R-V-G-G-A-T-Y-Q-V-P-M-E-V-R-Q-E-R-G-T-A-M-A-L-R-W-L-V-N-F-S-R-S-R-N-G-R-S-M-A-H-K-L-A-G-E-L-M-D-A-A-N-E-A-G-N-A-V-R-K-R-E-E-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-Y"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-T-A-I-A-Q-Q-K-I-R-I-R-L-K-A-F-D-R-R-M-L-D-L-S-C-D-K-I-I-E-T-A-D-N-T-A-A-T-A-I-G-P-I-P-L-P-T-K-R-K-I-Y-C-V-L-R-S-P-H-V-D-K-D-S-R-E-H-F-E-T-R-T-H-R-R-I-I-D-I-Y-S-P-S-A-K-T-I-D-A-L-M-K-L-D-L-P-S-G-V-D-I-E-V-K-L"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-Q-K-H-I-V-K-D-L-E-L-L-A-A-N-A-A-A-K-E-G-F-E-I-I-R-L-E-V-L-A-Q-M-K-P-M-K-I-Q-L-Q-I-R-H-K-N-G-S-D-V-S-L-E-D-C-S-R-L-S-R-P-I-G-E-V-I-E-N-S-K-L-I-N-Q-S-Y-I-L-E-I-S-S-P-G-L-S-D-I-L-E-T-D-K-E-F-A-T-F-K-G-F-P-I-Q-V-S-T-K-N-K-S-N-S-T-I-L-Q-N-G-L-L-H-T-K-S-K-E-H-L-L-I-N-I-K-G-K-M-S-K-I-P-I-D-N-V-I-Q-V-R-L-A-S-P-T-D"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-N-N-S-A-K-K-R-I-Q-I-A-E-R-N-R-I-Q-N-R-T-Y-K-S-A-M-R-T-L-M-K-R-C-F-E-A-C-G-A-Y-S-E-K-P-S-E-D-A-K-K-D-I-Q-N-S-M-N-D-A-F-S-K-I-D-K-A-V-K-T-G-V-L-H-R-N-T-G-A-N-Q-K-S-R-L-T-S-V-V-K-K-T-I-E-P-V-V-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-D-S-L-I-F-A-T-E-G-F-A-L-N-L-N-L-F-E-T-N-V-I-N-L-A-V-V-A-F-G-L-Y-K-F-L-P-N-F-L-G-G-M-L-E-R-R-R-S-A-I-L-Q-D-L-K-D-A-E-D-R-L-A-K-A-S-E-S-L-K-Q-A-K-L-D-L-S-S-A-E-Q-K-A-G-K-I-R-T-D-C-Q-A-R-A-E-A-I-R-L-E-S-E-K-R-T-V-E-E-M-A-R-I-K-Q-G-A-A-S-D-L-N-V-E-A-A-R-V-S-G-Q-L-R-R-E-A-A-K-L-A-I-E-K-A-L-S-T-L-S-G-K-L-D-D-K-A-Q-D-K-F-L-K-Q-S-I-K-N-I-G-D-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-M-P-L-L-N-T-I-T-T-P-Y-A-E-A-F-L-Q-V-A-E-N-R-N-E-V-D-E-V-V-A-Q-S-K-S-L-L-E-L-W-G-Q-S-S-E-F-S-E-A-M-A-S-P-V-L-E-V-E-T-K-K-A-V-L-E-K-I-F-S-K-E-I-T-P-S-F-L-N-L-L-K-L-L-A-D-R-K-R-I-G-Y-L-D-A-V-L-E-R-L-L-E-L-Y-R-E-Q-R-N-I-A-L-A-T-V-T-S-A-T-S-L-N-E-D-Q-Q-A-E-I-L-K-T-V-Q-S-V-A-G-T-D-N-L-E-L-N-L-K-V-D-P-N-L-I-G-G-F-V-V-N-V-G-S-K-V-I-D-A-S-L-S-S-Q-V-R-R-L-G-L-A-L-A-K-V-S"} +{"text": "### FUNCTION Probably a ribosomal protein or a ribosome-associated protein ### SEQUENCE -M-L-G-A-A-E-V-L-A-S-A-T-F-D-A-D-G-V-P-S-G-H-T-P-K-A-D-E-G-R-F-L-L-K-I-L-W-L-P-D-N-V-A-L-A-V-D-Q-I-V-G-G-G-T-S-P-L-T-A-Y-F-F-W-P-R-E-D-A-W-E-T-L-K-T-E-L-E-D-K-A-W-I-T-D-N-E-R-V-E-V-L-N-K-A-T-E-V-I-N-Y-W-Q-E-E-G-K-G-K-T-L-E-E-A-K-L-K-F-P-E-V-T-F-C-G-T-A"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-I-K-A-G-F-D-S-K-D-L-A-K-R-G-E-S-L-I-R-Q-A-S-N-R-Y-L-T-T-V-R-I-A-F-R-A-K-Q-R-R-F-D-D-F-D-G-L-L-E-E-S-S-V-K-P-V-Q-R-S-I-I-E-L-S-D-E-Q-D-Q-P-D-L-L-P-G"} +{"text": "### FUNCTION Unknown Resembles PsbF, one of the subunits of the photosystem II reaction center However, it encodes asparagine rather than histidine at the site PsbF uses to bind heme ### SEQUENCE -M-V-L-K-T-L-I-V-I-A-P-I-L-I-A-A-F-S-T-I-F-W-L-S-Y-W-G-V-F-K-W-E-D-N-Q-L-G-F-E-N-Y-Q-D-W-E-D-S-G-V-I-P-E-N-R-P-K-G-G-Y-P-V-F-T-V-R-T-L-A-V-N-A-L-G-I-P-T-V-F-F-L-G-A-I-F-A-M-Q-F-V-R-R-G-I-F-I-A"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-I-G-S-K-L-K-E-A-I-R-S-Y-S-D-F-P-K-K-G-I-L-F-H-D-I-S-P-I-F-C-K-P-D-L-Y-Q-E-L-I-E-E-M-A-K-S-E-I-L-N-S-S-D-A-I-I-S-I-D-A-R-G-F-L-F-G-S-C-I-S-L-K-L-S-K-P-L-I-L-A-R-K-A-G-K-L-P-G-P-I-L-S-S-T-Y-N-L-E-Y-G-E-N-S-L-S-I-Q-K-E-S-L-N-E-F-K-N-F-A-I-I-D-D-V-L-A-T-G-G-T-I-N-C-V-K-S-L-L-T-S-H-N-K-N-I-S-G-A-C-V-V-I-E-L-L-A-L-K-A-R-E-K-L-D-F-P-I-Y-S-T-L-T-L"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-F-D-F-M-T-P-N-K-T-K-N-S-T-V-G-N-Y-A-I-V-E-T-S-G-T-Q-F-W-L-E-A-D-R-Y-Y-D-I-D-R-I-N-A-N-V-D-E-T-V-T-L-D-K-V-L-L-I-N-D-Q-K-G-F-A-I-G-K-P-Y-I-K-G-A-S-V-Q-L-K-V-M-A-H-K-R-G-P-K-I-I-V-Y-K-M-R-P-K-K-K-T-R-T-K-N-G-H-R-Q-E-L-T-R-V-M-V-T-S-I-S-N-G-E-K-P-K-K-A-T-T-S-A-K-P-N-T-K-K-P-S-T-A-V-K-S-S-K-V-E-K-T-P-E"} +{"text": "### FUNCTION Component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria ### SEQUENCE -M-S-P-R-K-T-Y-I-L-K-L-Y-V-A-G-N-T-P-N-S-M-R-A-L-T-T-L-R-E-I-L-Q-T-D-F-K-G-V-Y-A-L-K-V-I-D-V-L-K-N-P-Q-L-A-E-E-D-K-I-L-A-T-P-T-L-A-K-I-L-P-P-P-V-R-R-I-I-G-D-L-S-D-R-E-R-V-L-I-G-L-D-L-L-F-E-E-L-S-E-S-D-F-F-S-G-S-P-D-S-E-F-S-S-D-E-G-K-S"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-P-I-G-T-P-S-V-P-Y-R-L-P-G-S-Q-F-E-R-W-V-D-I-Y-T-R-L-G-A-E-R-I-L-F-L-G-Q-E-V-T-D-G-V-A-N-S-L-V-A-Q-M-L-Y-L-D-S-E-D-S-T-K-P-I-Y-L-Y-I-N-S-P-G-G-S-V-T-A-G-L-A-I-Y-D-T-M-K-Y-V-K-S-D-V-V-T-I-C-V-G-L-A-A-S-M-G-A-F-L-L-S-A-G-T-K-N-K-R-L-A-L-P-H-S-R-I-M-I-H-Q-P-L-G-G-T-S-Q-R-Q-A-S-D-I-E-I-E-A-K-E-I-L-R-I-K-D-M-L-N-R-S-M-A-E-M-T-G-Q-P-F-E-K-I-E-K-D-T-D-R-D-Y-F-L-S-A-K-E-A-K-D-Y-G-L-I-D-K-V-I-S-H-P-N-E-A"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-R-D-V-K-R-K-K-L-V-E-R-Y-A-S-K-R-K-K-L-L-D-Q-F-H-S-A-K-D-P-M-E-R-L-E-I-H-R-K-I-Q-A-L-P-R-N-S-A-P-S-R-M-R-N-R-C-W-A-T-G-K-P-R-G-V-Y-R-D-F-G-L-C-R-N-Q-L-R-E-R-A-H-K-G-E-L-P-G-V-V-K-S-S"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-S-A-D-F-K-E-A-S-S-P-T-D-S-S-E-T-L-L-E-Q-I-V-K-G-S-R-K-T-S-N-Y-I-V-A-S-M-L-A-V-G-G-I-G-F-S-L-A-S-L-S-S-Y-F-G-I-D-L-L-P-L-G-N-P-S-T-L-I-F-V-P-Q-G-L-F-M-G-F-Y-G-I-A-A-T-F-I-S-V-Y-L-W-A-L-I-K-V-D-Y-G-S-G-L-N-R-F-D-K-N-K-G-V-L-S-V-S-R-K-G-L-L-K-E-I-L-V-E-I-P-I-D-D-I-Q-A-V-K-L-E-V-R-E-G-F-N-P-R-R-R-I-T-L-R-L-Q-G-R-R-D-L-P-I-S-E-V-G-G-P-Q-P-L-L-S-L-E-Q-E-G-A-E-I-A-R-F-L-K-V-N-L-E-G-L-S-N"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-A-S-E-I-F-G-T-A-A-I-F-W-V-L-I-P-A-G-L-L-G-G-A-L-L-L-K-L-Q-G-E"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-I-E-P-L-L-C-G-I-V-L-G-L-V-P-I-T-L-L-G-L-F-V-A-A-W-N-Q-Y-R-R-G-S-A-I-P-D-W-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-P-N-S-L-F-K-K-K-L-S-P-I-K-P-G-D-P-I-D-Y-K-D-V-E-T-L-K-K-F-I-T-E-R-G-K-I-L-P-R-R-L-T-G-L-T-A-K-Q-Q-R-D-L-T-T-A-V-K-R-A-R-I-I-A-L-L-P-F-V-N-P-E-G"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-I-P-I-V-V-E-E-T-G-R-G-E-R-A-F-D-I-Y-S-R-L-L-R-E-R-I-V-F-L-G-E-Q-V-T-N-D-S-A-N-R-I-V-A-Q-L-L-F-L-E-A-E-D-P-E-K-D-I-F-L-Y-I-N-S-P-G-G-S-V-Y-D-G-F-G-I-F-D-T-I-Q-H-I-K-P-D-V-H-T-V-C-V-G-L-A-A-S-M-G-A-F-L-L-C-A-G-A-K-G-K-R-S-S-L-Q-H-S-R-I-M-I-H-Q-P-L-G-G-A-R-G-Q-A-T-D-I-R-I-Q-A-D-E-I-L-F-L-K-Q-K-L-N-T-E-L-S-N-R-T-G-Q-P-L-S-K-I-A-E-D-T-D-R-D-F-Y-M-S-P-S-E-A-I-S-Y-G-I-I-D-N-V-L-N-K-K-P-V-S-V-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-L-F-T-F-A-W-A-S-L-A-A-I-F-T-F-S-I-A-M-V-V-W-G-R-N-G-D-G-T-I-D-L"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-V-R-P-K-P-T-S-V-L-S-F-D-Y-G-H-K-R-I-G-L-A-G-C-D-P-L-G-I-T-V-T-A-L-S-P-I-H-R-I-S-F-Q-K-D-L-T-L-I-K-S-L-C-I-E-R-E-I-K-G-L-I-V-G-L-P-L-D-E-S-G-Q-N-T-V-Q-S-I-H-C-Q-N-Y-G-I-K-I-A-K-E-L-D-L-P-L-A-W-V-N-E-H-S-S-S-W-D-A-G-Q-K-Y-N-L-Q-N-D-R-T-G-K-L-D-S-A-V-A-A-L-L-L-E-Q-W-L-R-E-G-P-E-L-Q-P-V-S-K-L-D-S-P-R-I-K-F"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-L-N-P-S-R-F-R-I-L-A-I-G-K-V-R-K-S-W-I-Q-N-G-L-E-V-Y-R-K-R-L-P-G-L-S-I-T-E-I-R-D-G-D-I-K-K-E-S-R-A-I-I-S-S-I-K-K-D-E-L-L-I-A-L-C-E-E-G-E-K-F-T-S-M-D-F-S-H-W-L-Q-N-L-G-S-S-R-I-V-F-A-I-G-G-T-N-G-L-S-Q-E-V-K-T-S-A-D-L-C-I-S-L-S-A-L-T-F-P-H-E-M-A-R-L-I-L-A-E-Q-L-Y-R-A-I-S-I-A-K-G-S-P-Y-H-R-E"} +{"text": "### FUNCTION Manganese-binding polypeptide with L-arginine metabolizing enzyme activity Component of the core of photosystem II ### SEQUENCE -M-L-N-L-L-V-I-T-L-P-I-L-A-A-I-G-W-V-T-L-N-I-Q-K-P-A-R-E-Q-W-D-R-Q-F-G-D-N-K-P-F"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-T-Q-E-V-E-L-N-M-Q-K-S-V-E-A-C-Q-R-N-F-N-T-I-R-T-G-R-A-N-T-S-L-L-D-R-L-T-V-E-Y-Y-G-A-D-T-P-L-K-S-L-A-T-I-S-T-P-D-S-Q-T-L-A-I-Q-P-F-D-L-G-S-L-G-L-I-E-K-A-I-S-I-S-D-L-G-F-T-P-N-N-D-G-K-I-I-R-I-N-I-P-P-L-T-E-E-R-R-K-Q-F-C-K-L-A-S-K-Y-A-E-E-A-K-I-S-L-R-N-I-R-R-D-A-I-E-K-I-K-G-S-E-K-D-G-E-F-S-E-D-Q-S-R-D-Q-Q-D-S-I-Q-K-I-T-N-K-Y-I-N-E-I-E-K-N-L-S-G-K-E-E-E-I-L-K-V"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-T-E-D-L-K-N-T-S-P-S-K-E-E-S-N-E-I-E-E-S-S-K-A-T-P-K-A-T-R-E-T-K-P-K-D-S-P-S-K-T-K-L-S-A-Q-A-L-I-A-Q-F-E-K-S-Q-Q-K-K-K-V-P-E-V-Y-V-G-D-T-V-R-V-G-V-R-I-S-E-G-N-K-E-R-V-Q-P-Y-E-G-V-I-I-A-K-R-H-G-G-L-N-Q-T-I-T-V-R-R-I-F-Q-G-V-G-V-E-R-V-F-M-V-H-S-P-Q-V-A-S-I-K-V-E-R-R-G-K-V-R-R-A-K-L-F-Y-L-R-D-R-V-G-K-A-T-R-V-K-Q-R-F-D-R"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-T-N-Y-N-G-L-I-V-I-T-G-P-S-G-V-G-K-G-T-L-V-K-K-L-L-L-E-N-P-E-I-W-L-S-I-S-A-T-T-R-T-P-R-E-G-E-I-N-G-K-D-Y-F-F-L-N-K-K-E-F-I-D-L-V-D-K-E-G-F-L-E-W-A-E-F-A-G-N-F-Y-G-T-P-R-A-Q-A-Q-E-K-I-S-V-G-K-K-V-L-L-E-I-E-L-D-G-A-R-Q-V-R-K-T-F-P-E-G-F-Q-I-F-I-A-P-P-S-F-E-E-L-E-K-R-I-R-T-R-G-T-D-S-E-L-A-I-Q-S-R-L-N-R-A-K-E-E-L-L-A-K-N-E-F-D-A-I-V-I-N-D-Q-L-D-I-A-L-L-E-I-K-K-L-I-K-S"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-L-I-S-R-L-R-A-V-V-A-G-D-D-Y-L-D-G-D-F-D-E-L-D-Y-E-T-G-D-D-F-D-T-G-N-D-G-G-G-N-Y-S-S-G-L-A-A-L-S-N-A-N-P-F-N-N-R-G-G-S-S-K-V-I-G-M-P-G-I-S-T-A-A-A-E-V-S-L-M-E-P-R-S-F-D-E-M-P-K-A-I-Q-A-L-R-E-R-K-T-V-I-L-N-L-T-M-M-E-P-D-Q-A-Q-R-A-V-D-F-V-A-G-G-T-F-A-I-D-G-H-Q-E-R-V-G-E-S-I-F-L-F-A-P-S-C-V-T-V-T-N-S-F-Q-E-E-P-S-P-S-S-V-M-N-K-D-N-E-G-P-V-S-E-S-V-M-A-P-E-P-A-W-G-A-S-V-P-S-A-I"} +{"text": "### FUNCTION Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase ### SEQUENCE -M-A-I-S-R-G-D-K-V-R-V-K-R-P-E-S-Y-W-Y-N-E-I-G-K-V-A-S-V-D-T-S-G-I-K-Y-P-V-V-V-R-F-E-K-V-N-Y-S-A-F-S-G-V-D-G-G-N-N-T-N-N-F-A-E-A-E-L-E-A-V"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-S-T-L-K-K-P-N-L-S-D-P-K-L-R-A-K-L-S-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-V-V-I-L-G-T-I-A-C-V-V-G-L-A-V-L-D-P-A-F-L-G-D-K-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-L-Y-P-V-F-Q-I-L-R-V-V-P-N-K-L-L-G-I-A-L-Q-T-L-I-P-L-G-L-I-L-I-P-F-I-E-N-V-N-K-F-S-N-P-F-R-R-P-V-A-M-A-F-F-L-F-G-T-A-L-T-I-Y-L-G-I-G-A-C-L-P-I-D-K-S-L-T-L-G-L-F"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-T-L-R-D-I-L-N-K-L-M-G-R-Q-P-A-S-A-A-K-A-R-E-R-L-Q-L-V-L-A-H-D-R-T-D-L-S-P-D-L-L-E-Q-M-R-E-E-I-L-S-V-V-A-K-Y-V-E-I-D-F-E-E-G-A-V-S-L-E-T-E-D-R-M-T-A-L-V-A-N-L-P-I-K-R-T-L-S-G-E-I-K-I-K-E-Q-S-S-A-D-N-S-A-K-A-V-S"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-T-T-N-F-G-F-I-I-S-L-L-F-V-G-I-P-T-I-F-L-V-G-L-Y-I-S-T-S-D-G-E-K-S-S-F-F-S-D-S-S-K-G-K-L-G-P-K-S"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-F-T-Y-T-L-L-M-T-L-G-V-V-T-L-F-F-A-V-A-F-R-D-P-P-K-F-D-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Q-C-P-S-C-Q-N-T-D-S-R-V-L-E-S-R-S-A-D-A-G-K-C-V-R-R-R-R-E-C-L-N-C-D-F-R-F-T-T-Y-E-R-V-E-T-I-P-V-T-V-I-K-R-S-N-A-K-E-I-F-C-R-S-K-L-L-N-G-L-T-R-A-C-E-K-T-S-I-N-N-Q-K-I-E-A-I-V-D-E-I-E-T-H-L-Q-Q-S-N-L-K-E-I-S-S-V-D-L-G-E-M-I-L-L-H-L-K-S-V-N-E-V-A-Y-I-R-F-A-S-V-Y-R-Q-F-N-G-I-E-D-F-I-D-T-L-E-S-F-K-P-S-N-K-F-A-A-I-S"} +{"text": "### FUNCTION Green-light absorbing phycoerythrin of unknown function ### SEQUENCE -M-L-D-A-F-S-R-A-V-V-S-A-D-S-K-G-A-T-I-G-S-A-E-L-S-S-L-R-K-Y-V-A-D-A-N-K-R-I-D-A-T-L-A-I-T-Q-N-V-S-C-I-A-A-D-A-I-S-G-M-V-C-E-N-T-G-L-T-Q-P-G-G-H-C-Y-P-T-R-R-M-A-A-C-L-R-D-G-E-I-I-L-R-Y-V-S-Y-A-L-L-A-G-D-P-S-V-L-D-D-R-C-I-N-G-L-K-E-T-Y-I-A-L-G-V-P-L-S-N-A-I-R-A-I-E-I-M-K-I-A-T-V-A-I-M-T-E-T-N-S-G-R-K-M-F-E-G-I-N-S-G-S-G-A-E-C-K-D-I-A-S-E-A-A-S-Y-F-D-R-V-I-D-A-L-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-S-K-L-K-G-P-D-G-R-L-P-D-R-L-P-D-G-R-P-A-V-S-W-E-R-R-W-T-E-G-Q-L-P-L-W-L-V-A-T-A-G-G-I-A-V-I-F-V-L-G-I-F-F-Y-G-S-Y-T-G-V-G-S-A"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-Q-V-N-P-N-P-N-K-L-S-V-E-L-N-R-T-S-L-Y-L-G-L-L-L-V-F-V-L-G-I-L-F-S-S-Y-F-F-N"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-N-L-P-I-K-S-N-A-A-S-K-E-K-L-L-T-L-L-A-L-K-A-Y-K-N-G-N-F-T-L-S-S-G-N-K-S-N-H-Y-V-N-C-K-P-V-S-L-S-G-N-G-L-L-L-L-S-N-M-M-L-E-N-V-E-P-D-S-L-A-V-A-G-L-T-L-G-A-D-P-L-V-C-G-V-A-L-A-A-T-Y-A-G-R-K-L-D-A-L-I-V-R-K-E-P-K-G-Y-G-T-A-S-W-L-E-G-P-L-P-P-A-G-S-V-I-T-V-L-E-D-V-V-T-T-G-R-S-S-L-K-A-V-N-Q-L-Q-N-A-G-Y-R-V-N-R-I-I-S-I-V-D-R-Q-E-G-G-A-F-E-I-K-K-A-G-L-D-L-V-S-L-F-V-L-D-E-V-Y-E-K-F-K-N-T"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-P-L-T-L-D-L-L-A-Q-L-P-E-A-Y-Q-L-Y-A-P-T-V-D-V-L-P-L-I-P-L-L-F-F-L-L-V-F-V-W-Q-A-A-V-G-F-R"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-A-L-K-I-S-V-Y-T-V-V-F-F-F-V-G-V-F-L-F-G-F-L-A-S-D-P-T-R-T-P-A-R-K-D-L-E-S-P-Q-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-S-S-P-A-L-S-I-A-I-T-I-L-I-V-L-L-G-L-T-A-F-G-V-Y-T-A-F-G-P-P-N-R-A-L-D-D-P-W-D-D-H-D-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-G-Q-K-T-A-V-G-S-L-L-K-S-I-G-N-S-G-Q-G-K-V-V-A-G-W-G-A-V-P-V-M-A-F-V-G-V-L-L-L-V-F-L-V-I-L-L-Q-I-Y-N-Q-S-L-L-L-Q-G-F-S-V-D-W-N-G-V-N"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-T-R-I-S-S-D-D-V-R-K-V-S-K-L-A-R-L-E-I-S-E-E-H-V-E-T-Y-A-N-Q-L-E-E-I-L-E-Y-I-A-Q-L-E-K-I-D-T-K-N-I-P-P-T-T-R-A-V-E-V-V-N-V-L-R-E-D-I-V-D-K-S-N-V-R-D-K-I-L-D-L-A-P-N-R-E-G-Q-F-Y-R-V-P-K-I-L-A-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-T-A-V-I-K-L-A-L-Q-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-A-F-C-K-E-Y-N-A-R-T-Q-D-K-A-G-F-V-I-P-V-E-I-S-V-F-E-D-R-S-F-T-F-I-T-K-T-P-P-A-S-V-L-I-T-K-A-A-G-I-A-K-G-S-G-D-S-A-K-G-Q-A-G-S-I-N-R-A-Q-L-E-E-I-A-K-T-K-L-P-D-L-N-C-N-N-I-E-S-A-M-K-V-I-A-G-T-A-R-N-M-G-V-S-V-S-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-G-R-T-L-E-S-K-K-Q-I-V-E-E-I-K-G-L-L-D-K-A-D-M-A-L-V-L-D-Y-Q-G-L-S-I-K-E-M-S-D-L-R-S-R-L-E-Q-S-S-G-I-C-K-V-T-K-N-T-L-M-R-K-A-I-N-G-D-A-T-W-S-G-L-E-S-L-L-N-G-T-N-A-F-V-L-V-K-G-D-V-G-S-A-L-K-A-V-Q-A-F-Q-K-E-T-K-K-S-E-T-K-G-G-L-Y-E-G-K-L-L-T-Q-D-E-I-K-A-I-A-A-L-P-S-K-E-A-L-M-A-Q-I-A-G-A-L-N-S-I-T-T-K-I-A-V-G-V-N-E-I-P-S-G-L-A-R-S-L-K-Q-H-A-E-N-S-E-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-K-K-T-D-E-I-L-D-S-L-K-S-L-S-L-L-E-A-S-E-L-V-K-Q-I-E-E-A-F-G-V-S-A-A-A-S-A-G-V-V-M-A-A-P-G-A-A-T-G-G-G-E-A-A-A-E-E-K-T-E-F-D-V-V-L-E-S-F-D-A-S-A-K-I-K-V-L-K-E-V-R-N-A-T-G-L-G-L-G-D-A-K-A-M-V-E-A-A-P-K-T-I-K-E-G-A-S-K-E-D-A-E-A-L-K-K-A-I-E-A-V-G-G-K-V-T-L-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-Q-N-L-N-D-S-S-I-S-V-D-L-T-I-D-L-S-L-S-G-F-T-F-D-L-M-K-D-S-I-D-S-K-M-I-D-L-I-M-D-C-D-T-W-R-N-S-I-V-S-W-F-D-C-I-L-M-Q-P-N-L-T-C-P-Q-I-V-R-K-N-R-F-F-S-M-G-L-L-F-T-N-D-L-S-I-R-Q-M-N-K-E-W-R-K-K-D-E-S-T-D-V-L-S-F-P-A-I-D-E-H-I-V-L-P-P-N-Q-F-L-E-L-G-D-I-I-V-S-V-E-T-A-F-K-Q-A-K-I-H-N-H-S-L-M-H-E-L-R-W-L-V-S-H-G-F-L-H-L-L-G-W-D-H-P-S-S-A-S-L-N-E-M-L-S-F-Q-E-L-L-L-K-T-P-N-G-S-P-L-R-N-S-M-R-D-Y"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA biosynthesis ### SEQUENCE -M-Q-S-K-T-L-Q-N-W-L-H-L-Q-R-I-V-R-F-G-D-T-D-A-A-G-V-I-H-F-H-Q-L-L-R-W-S-H-E-A-W-E-E-S-L-D-R-Y-G-L-K-A-V-D-V-F-P-S-S-L-G-I-S-T-S-T-S-V-A-L-P-I-V-H-C-E-A-D-F-F-L-P-I-G-I-G-D-K-L-N-V-Q-L-V-P-V-R-L-N-I-G-S-F-E-V-Q-F-T-F-Q-R-R-E-Q-N-V-A-V-A-L-V-R-H-R-S-I-D-S-D-S-R-R-L-C-D-L-P-E-G-I-D-R-W-L-E-A-S-S-L-H-R-G-V-S-A-I"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-T-D-P-L-L-K-C-T-T-R-H-I-R-I-F-T-A-I-T-Q-N-N-N-L-I-E-D-S-D-H-L-T-M-D-L-D-P-D-N-E-F-L-W-E-N-Q-A-I-E-K-V-Q-N-R-F-S-E-L-V-E-S-Q-V-G-Q-E-L-S-D-Y-V-L-R-K-I-G-S-D-L-E-S-Y-I-R-Q-M-L-Q-A-G-E-V-S-Y-N-P-D-S-R-V-L-N-Y-S-M-G-L-P-R-T-P-E-L-L"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-S-S-N-N-K-D-N-F-L-D-K-A-F-T-V-I-A-E-G-I-V-K-M-M-P-I-A-A-K-E-K-Q-A-Y-I-Y-Y-R-E-G-F-A-A-Q-N-N-G-D-Y-S-E-A-L-E-N-Y-E-E-S-L-K-L-E-E-N-A-I-D-R-G-E-T-L-K-N-M-A-I-I-Y-M-S-N-G-D-E-D-K-A-L-D-T-Y-Q-K-A-L-E-Q-N-P-K-Q-P-S-C-L-K-N-M-G-L-I-Y-E-K-R-G-R-A-L-Q-Q-N-G-K-Q-D-E-S-D-I-W-F-D-K-A-A-E-V-W-T-K-A-V-R-L-Y-P-G-G-Y-L-D-I-E-N-W-L-K-T-T-G-R-S-K-V-D-I-Y-L"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-Q-S-R-R-V-E-K-V-A-A-L-I-R-K-E-M-S-E-L-L-S-N-G-I-R-D-Q-R-V-N-T-T-M-I-T-I-T-E-V-E-V-S-G-D-L-Q-H-C-K-I-F-V-S-I-Y-G-N-E-I-Q-K-D-E-V-F-S-G-L-E-A-S-Q-S-F-L-K-G-E-L-G-R-R-L-Q-M-R-R-A-P-E-V-V-F-K-L-D-R-G-M-E-K-G-I-S-V-L-N-L-L-E-K-L-E-A-E-R-N-I-K-D-K-K-L-I-E-F-Q-E"} +{"text": "### FUNCTION Involved in the binding and/or turnover of quinones at the Q site of Photosystem II ### SEQUENCE -M-A-F-T-L-L-F-G-A-G-V-S-G-D-V-A-T-A-S-A-V-G-M-I-G-S-F-L-A-A-A-A-L-I-V-V-P-A-A-S-F-L-L-W-V-S-Q-K-D-A-L-E-R-G-R"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-S-N-D-F-R-T-G-T-T-I-E-L-D-G-A-V-W-R-V-V-E-F-L-H-V-K-P-G-K-G-S-A-F-V-R-T-K-L-K-A-V-Q-A-G-N-V-V-E-K-T-F-R-A-G-E-M-V-P-Q-A-L-L-E-K-A-T-L-Q-H-T-Y-M-E-S-G-D-Y-V-F-M-D-M-S-T-Y-E-E-T-R-L-T-A-N-Q-I-G-D-S-R-K-Y-L-K-E-G-M-E-V-N-V-V-S-W-N-E-K-P-L-E-V-E-L-P-N-S-V-V-L-E-V-K-E-T-D-P-G-V-K-G-D-T-A-T-G-G-T-K-P-A-I-L-E-T-G-A-Q-I-M-V-P-L-F-I-S-V-G-E-K-I-K-V-D-T-R-N-D-S-Y-L-G-R-E-N"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-G-F-G-L-P-N-F-G-Q-I-T-E-A-F-K-K-A-Q-Q-I-Q-Q-D-A-Q-K-L-Q-E-E-L-D-D-M-E-L-E-G-T-N-E-D-G-R-V-T-V-W-L-S-G-N-Q-Q-P-I-R-V-K-V-E-N-S-I-L-K-E-E-E-E-I-V-E-A-A-I-L-E-A-M-Q-K-A-H-E-I-S-T-S-N-M-K-S-R-M-Q-E-L-T-G-G-L-N-L-N-L-P-G-I-N-D-D-N"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-A-N-I-G-W-G-E-M-L-V-L-V-M-V-G-L-V-V-L-G-P-E-R-L-P-G-A-I-R-W-A-A-S-A-L-R-Q-A-R-D-Y-L-S-G-V-T-S-Q-L-R-E-D-I-G-P-E-F-D-D-L-R-G-H-L-G-E-L-Q-K-L-R-G-M-T-P-R-A-A-L-T-K-H-L-L-D-G-D-D-S-L-F-T-G-D-F-D-R-P-T-P-K-K-P-D-A-A-G-S-A-G-P-D-A-T-E-Q-I-G-A-G-P-I-P-F-D-S-D-A-T"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-K-S-A-Q-K-R-I-R-Q-T-K-T-R-T-E-R-N-R-Y-Y-K-T-R-I-K-N-I-V-R-D-L-R-E-A-V-L-N-K-D-V-A-K-A-Q-E-A-L-K-I-A-N-K-E-L-H-K-Y-V-S-K-G-I-L-K-K-N-T-A-A-R-K-V-S-R-L-N-A-S-V-K-K-I-A-Q-S-A"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-M-K-K-G-I-H-P-E-Y-I-P-C-K-V-T-C-V-T-S-G-K-Q-L-E-V-L-S-T-K-S-E-L-R-I-D-I-S-S-F-C-H-P-F-Y-T-G-S-D-K-I-T-D-I-T-G-R-V-E-K-F-R-Q-K-Y-N-M-K"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-A-H-T-A-F-E-T-S-L-D-T-L-L-E-E-P-K-M-Y-R-V-L-L-L-N-D-D-W-T-A-M-D-F-V-A-R-I-L-M-E-V-F-D-K-T-S-D-E-A-T-A-I-T-L-K-I-H-N-D-G-K-G-V-C-G-I-Y-T-Y-D-I-A-E-L-K-M-Q-I-V-S-Q-M-A-K-Q-H-G-Y-P-L-R-V-I-T-E-E-M-P"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-L-E-G-Q-I-R-E-S-I-S-K-S-Q-A-K-A-L-R-N-D-G-Y-L-I-A-N-I-Y-G-K-G-Q-Q-N-I-H-C-A-F-K-L-N-D-F-I-K-A-M-K-Q-K-T-T-L-I-F-P-V-Q-V-G-G-K-T-L-E-V-V-I-Q-E-Y-Q-K-D-P-V-T-N-T-L-I-H-V-D-L-L-L-A-Q-K-G-I-L-N-K-Y-K-V-P-V-I-V-K-G-N-A-K-G-L-K-N-K-G-V-L-F-I-S-T-K-R-I-S-V-K-C-A-A-E-N-L-P-N-A-Y-E-I-D-V-S-D-L-D-V-G-D-S-I-L-I-R-D-L-P-Q-F-D-N-V-N-V-L-N-R-P-S-V-A-V-V-G-V-I-K-A-K"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-G-V-G-I-F-E-V-L-V-I-L-I-V-A-V-I-A-L-G-P-N-K-L-P-Q-T-I-V-D-I-V-K-F-F-R-A-V-K-K-T-M-A-E-A-K-E-T-F-D-K-E-I-Q-L-S-E-I-K-Q-E-A-L-K-Y-K-D-T-L-E-S-E-V-N-K-L-T-K-D-I-R-L-D-E-L-R-E-I-S-V-D-S-L-T-K-P-L-Q-E-T-K-E-V-L-S-E-E-A-K-N-L-Q-S-T-L-E-S-L-N-S-D-I-S-Y-E-S-S-A-A-A-Q-T-P-T-T-Q-E-S-I-P-T-D-S-T-R-E-I-A-Y-A-T-Q-K-P-Q-N-S-I-D-S-I-N-S-K-E-S-S-V-D-S-L-H-S-P-S-I-V-E-S-T-Q-S-S-S-S-K-D-S"} +{"text": "### FUNCTION Specifically methylates the N7 position of guanine in position 527 of 16S rRNA ### SEQUENCE -M-L-P-E-V-C-Y-K-H-F-T-I-F-G-D-E-L-L-K-W-N-K-I-H-N-L-T-G-A-S-S-I-E-S-V-M-E-N-I-F-D-S-L-Y-P-L-R-F-I-D-D-F-T-S-C-M-D-I-G-S-G-G-G-F-P-A-I-P-L-A-I-A-K-P-Q-S-H-F-I-L-I-E-P-R-N-K-R-S-C-F-L-Q-N-I-I-I-Q-L-E-L-N-N-V-Q-V-R-P-I-R-I-Q-D-V-P-I-A-E-V-N-N-L-D-L-I-T-S-R-A-L-M-D-A-K-E-L-I-S-L-S-R-K-F-L-K-S-E-G-Y-F-L-L-Y-K-G-T-R-F-R-Q-E-T-P-S-M-S-I-E-E-C-F-T-R-E-N-R-I-Y-Y-Y-K-H-S-R-D-L"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-K-S-V-T-K-K-K-N-V-K-K-N-I-A-R-G-I-V-C-I-S-A-S-F-N-N-T-N-V-T-I-T-D-E-M-G-N-V-L-C-W-A-T-A-G-G-L-G-F-K-G-S-K-K-S-T-P-Y-A-A-Q-Q-A-V-E-S-A-M-E-K-A-K-E-H-G-I-K-E-V-G-I-K-V-Q-G-P-G-S-G-R-E-T-A-V-K-S-V-G-A-V-E-G-I-K-V-L-W-L-K-D-I-T-P-L-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-L-P-K-K-K-R-V-E-Y-A-L-T-Y-I-Y-G-I-G-L-K-S-S-Q-D-I-L-K-A-V-N-I-S-F-D-K-R-V-S-D-L-S-E-D-E-V-S-S-I-A-K-K-I-Q-E-S-Y-M-V-E-G-D-L-R-K-K-V-T-M-D-I-K-S-L-M-D-L-G-S-Y-R-G-L-R-H-R-K-G-L-P-V-R-G-Q-T-T-K-N-N-A-R-T-R-K-G-K-K-K-T-V-G-S-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-E-V-D-G-K-V-I-E-A-L-P-N-A-T-F-R-V-Q-L-E-N-G-H-I-V-L-C-H-I-A-G-K-M-R-M-H-Y-I-K-I-L-P-G-D-M-V-K-I-E-L-T-P-Y-S-L-D-K-G-R-I-T-Y-R-H-K"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-E-I-N-R-E-E-F-S-E-V-V-V-N-I-G-R-V-T-K-V-V-K-G-G-R-R-F-R-F-N-A-L-V-V-V-G-N-K-N-G-L-V-G-F-G-L-G-K-A-K-E-V-P-D-A-I-K-K-A-I-D-D-A-F-K-N-I-I-K-V-N-I-K-G-T-T-I-A-H-D-I-E-H-K-Y-N-A-S-R-I-L-L-K-P-A-S-E-G-T-G-V-I-A-G-G-S-T-R-P-V-I-E-L-A-G-I-K-D-I-L-T-K-S-L-G-S-N-N-P-Y-N-V-V-R-A-T-I-D-A-L-A-R-I-K-A"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-T-D-K-V-L-K-R-K-Q-L-L-K-V-K-R-K-L-R-T-R-G-K-I-F-G-R-A-D-K-P-R-V-S-V-F-K-S-N-K-Y-F-Y-A-Q-A-I-N-D-E-L-G-V-T-L-A-S-V-D-G-K-K-L-G-L-G-N-N-K-E-N-A-K-Q-I-A-N-E-F-A-T-S-L-K-K-A-K-I-T-E-V-V-F-D-R-N-G-Y-L-Y-H-G-V-V-A-A-F-A-D-T-L-R-E-N-G-I-K-L"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-K-P-I-N-I-P-K-G-V-E-V-S-V-Q-G-S-K-I-L-F-K-G-A-K-E-Q-K-E-L-E-T-Y-G-R-V-Q-I-H-L-Q-D-G-T-L-S-F-A-C-V-D-S-Q-A-Q-S-R-A-Y-W-G-T-Y-R-A-L-A-N-N-I-I-V-G-L-S-Q-G-F-T-K-V-L-E-I-N-G-V-G-Y-K-A-N-I-S-G-K-N-L-E-M-A-L-G-F-S-H-P-V-I-Y-P-I-P-A-G-V-E-M-S-V-D-K-N-T-I-T-I-K-G-A-D-K-Q-Q-I-G-Q-I-A-A-E-I-R-K-F-R-P-P-E-P-Y-K-G-K-G-I-K-Y-S-D-E-M-I-V-R-K-A-G-K-T-S-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-N-D-I-I-A-D-S-L-T-R-I-R-N-A-S-M-R-R-L-E-V-T-T-L-Y-Y-A-K-I-V-V-S-I-V-E-V-F-K-T-K-G-F-I-K-D-Y-K-V-N-D-K-D-G-K-R-S-I-M-V-Q-L-A-Y-D-E-Q-G-K-S-A-I-N-E-I-K-R-I-S-K-P-G-R-R-V-Y-K-A-R-S-E-L-K-R-F-K-N-G-Y-G-T-I-V-V-S-T-S-K-G-V-V-A-N-D-E-A-Y-K-A-N-V-G-G-E-A-L-C-S-I-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-F-A-L-R-E-K-Y-K-N-E-I-I-S-Q-L-K-S-E-L-N-M-S-N-P-M-L-L-P-K-L-E-K-I-V-I-S-V-G-A-G-D-Y-A-K-D-S-K-I-M-Q-N-I-A-D-T-I-S-L-I-A-G-Q-K-A-V-I-T-L-A-K-K-S-V-A-G-F-K-M-R-E-G-M-P-M-G-V-K-V-T-L-R-G-K-M-M-Y-N-F-L-E-K-L-I-V-I-A-L-P-R-V-K-D-F-R-G-L-K-R-N-G-F-D-G-R-G-N-Y-S-F-G-L-N-E-Q-L-M-F-P-E-V-V-Y-D-D-I-M-V-T-H-G-M-N-I-T-I-V-T-S-T-H-S-D-K-E-A-F-K-L-L-E-L-L-G-M-P-F-A-K-G-R"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-K-F-K-I-K-K-G-D-M-V-Q-V-I-A-G-D-D-K-G-K-K-A-K-V-L-Q-V-L-P-K-Q-A-Q-V-I-V-E-G-C-K-V-V-K-K-A-I-K-V-S-E-K-N-P-K-G-G-F-V-S-K-E-M-P-M-S-I-S-N-V-K-K-A-E-G-D-N"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-S-F-T-R-L-S-V-A-D-N-S-G-A-K-E-I-M-C-I-K-I-L-G-G-S-H-R-R-Y-A-R-V-G-D-V-I-V-A-S-V-K-K-A-I-P-N-G-K-V-K-K-G-Q-V-V-K-A-V-V-V-R-T-K-K-E-I-H-R-E-N-G-S-L-V-R-F-D-D-N-A-A-V-I-L-D-A-K-K-E-P-I-G-T-R-I-F-G-P-V-S-R-E-V-R-Y-A-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-K-Q-A-H-T-R-V-I-Q-G-K-V-I-S-Q-A-G-N-K-S-I-V-I-L-V-E-R-K-V-V-H-S-K-Y-R-K-I-V-K-R-F-K-K-Y-T-I-H-D-E-N-Q-S-A-K-I-G-D-V-V-S-A-I-E-C-K-P-I-S-K-T-K-A-F-R-F-K-E-I-I-T-A-G-V-E-L"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-Y-R-K-Q-M-K-G-R-N-R-G-K-S-F-R-G-A-N-L-A-F-G-D-I-G-I-K-A-I-E-H-G-R-I-D-S-R-Q-I-E-S-A-R-I-A-M-T-R-H-I-K-R-A-G-K-V-W-I-R-V-F-P-D-K-P-L-T-A-K-P-L-E-T-R-M-G-K-G-K-G-G-V-E-K-W-V-M-N-I-K-P-G-R-L-I-Y-E-M-A-G-I-D-E-A-L-A-R-E-A-L-A-L-A-Q-S-K-L-P-F-K-T-K-I-I-T-S-E-S-E-N-E-I-Y"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-R-A-L-L-K-Y-I-R-L-S-P-T-K-A-R-L-V-A-R-Q-V-Q-G-M-N-A-E-I-A-I-A-S-L-E-F-T-P-N-K-A-A-R-V-I-S-K-V-I-A-S-A-V-A-N-G-G-Y-D-A-Q-D-V-I-I-L-S-C-R-V-D-A-G-P-V-L-R-R-F-M-P-R-A-K-G-R-A-T-P-I-R-K-P-M-A-H-I-L-V-E-V-G-T-Q-K-S-V-Q-Q-S-V-Q-S-T-K-A-K-A-K-G-A-K-N-I-K-S-E-D-S-K-N-S-L-K-V-T-E-S-K-A-D-S-K-V-D-A-A-Q-K-A-S-T-T-Q-E-K-A-E-S-K-T-K-V-A-K-A-K-V-A-T-T-K-S-T-A-T-R-K-T-T-K-K-K-T-E-G-E-E-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-I-K-K-G-P-F-V-D-D-Y-L-V-K-K-V-E-K-A-K-A-S-K-D-N-K-P-I-K-T-W-S-R-R-S-T-I-L-P-D-M-I-G-L-T-F-N-V-H-N-G-R-A-F-V-P-V-Y-I-T-E-N-H-V-G-Y-K-L-G-E-F-A-P-T-R-T-F-K-G-H-K-G-S-V-Q-K-K-I-G-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-A-D-I-T-D-I-K-S-I-L-Y-T-E-K-S-L-S-L-Q-E-S-G-V-L-V-V-Q-T-A-T-N-V-S-K-N-Q-L-K-E-I-F-K-E-Y-F-G-I-T-P-L-R-I-N-S-L-R-Q-E-G-K-V-K-R-F-R-G-K-I-G-Q-R-A-S-F-K-K-F-Y-V-K-I-P-E-G-A-K-L-D-A-L-S-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-E-F-I-V-E-K-I-G-M-S-R-T-I-G-T-K-S-E-A-V-T-L-L-R-V-L-G-A-K-V-C-E-I-Y-D-N-G-K-A-L-V-A-Y-S-Q-G-K-S-V-N-K-A-I-A-G-Q-Q-K-K-Y-S-L-S-K-E-F-N-R-F-A-T-L-K-V-S-N-K-E-V-G-E-L-D-V-A-S-L-S-E-A-K-R-V-Q-V-S-F-K-T-K-G-R-G-F-S-G-A-M-K-R-W-N-F-Q-G-G-P-G-A-H-G-S-R-F-H-R-R-L-G-S-I-G-N-R-E-W-P-G-R-V-Q-P-G-K-K-M-A-G-H-Y-G-N-E-L-V-S-A-K-N-D-I-M-S-F-D-K-Q-S-A-I-L-V-L-K-G-S-V-A-G-F-N-G-A-F-G-R-I-Q-I-I-K"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-E-R-I-R-L-R-L-K-A-Y-D-H-R-V-L-D-R-S-V-A-S-I-V-E-A-V-K-R-T-G-S-E-I-R-G-P-V-P-L-P-T-K-K-K-R-Y-T-V-L-R-S-P-H-I-N-K-D-S-R-E-Q-F-E-I-R-V-H-H-R-I-I-D-I-M-S-A-T-P-D-T-V-D-S-L-M-K-L-D-L-A-P-E-V-D-V-E-V-M-S-M-S-K"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-K-Q-K-I-A-D-S-I-R-A-V-Y-N-Y-K-P-G-V-I-F-R-D-I-T-T-L-I-G-D-A-E-V-F-K-E-V-I-N-I-L-R-S-R-Y-E-N-Q-S-I-D-F-I-A-A-I-E-A-R-G-F-I-F-G-S-A-L-A-Y-A-L-G-I-G-F-V-P-I-R-K-K-G-K-L-P-Y-N-T-I-S-E-K-Y-T-L-E-Y-G-T-D-E-L-H-I-H-T-D-A-F-R-D-K-K-N-A-K-V-V-L-I-D-D-L-I-A-T-G-G-T-A-E-A-S-V-K-L-I-K-S-I-G-A-Q-C-V-E-A-A-F-V-I-N-L-K-G-L-E-G-E-K-K-L-A-P-Y-T-Q-V-F-S-I-V-E-Y-E-G-K"} +{"text": "### FUNCTION Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis ### SEQUENCE -M-Y-V-A-I-E-G-V-D-T-C-G-K-S-T-Q-I-Q-L-L-K-A-Y-Y-P-Q-A-V-F-T-K-E-P-G-G-S-I-I-G-E-H-I-R-D-L-V-L-F-A-P-K-K-Y-G-F-T-L-D-E-R-A-E-L-M-L-F-L-A-D-R-A-Q-H-Y-A-Q-V-L-L-P-H-K-D-K-L-I-I-S-D-R-S-V-I-S-G-I-A-Y-A-K-S-I-D-I-A-Q-S-I-A-L-N-D-F-V-L-R-G-M-L-P-D-L-V-V-I-L-E-L-D-E-K-S-L-K-E-R-I-E-S-K-S-H-D-N-I-E-S-R-G-I-S-Y-M-L-E-I-Q-K-C-F-K-N-V-V-T-Q-M-N-L-K-Y-I-V-L-D-A-T-Q-D-K-E-R-I-C-A-Q-I-R-E-H-I-N-I-L-V"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-I-M-P-T-L-D-M-D-K-D-T-F-T-Q-V-G-Y-L-Y-N-L-L-D-K-I-G-H-L-G-L-F-E-R-D-L-S-C-Y-M-L-E-V-L-A-V-D-S-Q-N-M-R-E-I-N-F-A-H-R-A-K-N-S-T-T-D-V-L-S-F-P-L-D-V-S-E-G-A-D-S-H-I-L-A-K-Q-M-K-I-C-L-G-S-V-V-I-N-Y-E-L-A-Q-K-V-A-K-Q-R-G-H-S-T-Q-D-E-I-S-L-L-F-I-H-G-F-L-H-I-L-G-Y-D-H-E-V-D-N-G-E-Q-R-A-L-E-Q-K-I-I-E-S-L-G-L-K-E-S-L-I-V-R-N-T-T"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-N-H-C-I-L-A-C-D-V-G-L-K-R-I-G-L-A-T-L-K-Q-E-I-I-L-P-L-P-P-I-I-R-I-N-R-N-Q-A-A-K-E-L-D-N-V-L-K-E-R-N-I-H-I-L-V-V-G-M-P-S-G-G-E-A-E-H-S-D-T-Q-K-R-I-S-H-F-I-S-L-L-S-F-E-G-E-I-C-F-V-N-E-D-Y-T-S-F-N-A-L-Q-S-L-S-Y-M-K-R-Q-N-R-A-R-A-Q-K-D-G-R-I-D-S-L-S-A-C-E-I-L-Q-R-Y-I-Q-S-Q-K-S"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-L-G-M-F-G-H-S-S-Q-K-S-A-T-L-A-R-E-R-L-K-L-V-L-S-H-E-R-T-A-N-I-P-Y-L-E-D-M-Q-K-E-I-L-Q-V-V-Q-K-Y-T-R-S-S-K-I-E-F-S-T-N-S-N-Q-N-I-N-T-L-E-V-E-I-T-L-G-N"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-K-A-Q-G-F-V-H-K-Y-G-D-N-V-D-T-D-V-I-I-P-A-R-Y-L-N-T-A-D-H-K-E-L-A-N-H-C-M-E-D-I-D-K-D-F-V-A-K-V-K-E-G-D-I-M-V-G-G-W-N-F-G-C-G-S-S-R-E-H-A-P-I-A-I-K-A-S-G-I-S-C-I-I-A-K-S-F-A-R-I-F-Y-R-N-A-I-N-I-G-L-A-I-I-E-S-E-E-V-A-Q-S-L-E-N-G-D-E-V-A-I-D-F-D-K-G-I-I-T-N-C-K-N-N-Q-Q-F-S-T-T-P-F-P-P-F-I-Q-E-I-I-N-A-N-G-Y-L-N-W-I-S-K-Q-K-A-N-A"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-R-N-R-Y-I-Q-S-F-Q-E-A-Q-I-G-K-K-Q-V-P-Q-F-K-A-G-D-T-L-R-L-G-I-K-I-Q-E-G-D-K-T-R-I-Q-H-F-E-G-V-C-I-S-I-R-G-N-G-V-D-R-T-F-T-T-R-K-M-G-A-N-N-I-G-V-E-K-T-F-P-L-Y-S-E-S-L-D-S-I-E-V-L-R-I-G-R-V-R-R-A-K-L-Y-Y-L-R-S-R-R-G-K-A-A-R-I-K-E-L-R-K"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-T-Y-E-L-K-M-P-I-L-G-F-D-A-T-K-I-E-L-E-K-I-D-E-T-F-S-K-I-R-G-L-D-G-K-Q-P-F-E-I-T-L-I-N-P-F-S-L-C-D-Y-A-F-T-I-P-T-A-D-E-R-L-L-D-L-D-E-S-R-G-D-K-V-E-V-Y-C-V-V-V-L-Q-K-P-I-E-N-S-V-V-N-L-M-A-P-F-V-F-N-P-A-N-A-C-A-L-Q-V-T-T-L-P-V-A-E-Y-P-Q-F-S-K-V-L-P-L-K-E-F-L-S-K-E-I-L-E-T-L-N-R"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-I-F-E-V-K-S-P-I-L-G-F-E-S-V-A-K-M-K-L-E-K-I-D-D-L-F-M-K-L-Y-N-A-E-G-E-V-P-H-F-T-L-V-N-P-F-L-L-R-E-Y-E-F-D-V-P-A-S-I-K-I-L-L-D-L-S-D-A-K-N-L-L-I-A-N-I-M-V-I-Q-Q-P-I-E-N-S-T-I-N-F-L-A-P-L-I-F-N-F-D-N-L-T-M-A-Q-V-V-L-D-S-T-Q-Y-P-L-Y-S-L-N-E-P-I-G-K-Y-Y-D-K-E-E-A-Q-K-G-E-Q-A-A-P-V-R-D-S-Q-K-K"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-D-T-L-R-T-E-E-I-A-A-K-A-L-K-R-V-H-N-D-R-Y-L-L-A-S-L-I-F-E-R-V-K-E-L-G-E-G-A-K-P-L-V-D-M-D-V-K-T-Y-K-L-P-D-I-A-M-R-E-I-A-E-G-K-V-E-L-T-S-I-E-D-R-E"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-Y-S-I-V-A-S-L-I-Q-M-C-E-S-H-A-K-E-H-N-A-A-S-I-A-K-V-C-I-A-V-G-E-R-S-G-V-D-S-A-L-V-K-S-A-F-E-T-F-R-L-D-S-P-L-C-Q-N-T-I-L-E-I-Q-S-Q-S-V-E-L-E-C-R-D-C-G-H-Y-F-Q-A-Q-N-L-T-Y-S-T-C-P-Q-C-Q-S-H-N-V-I-I-A-K-G-K-E-L-H-L-L-S-L-E-L-D-I-Q-S"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-A-V-I-Y-L-A-G-G-C-F-W-G-I-Q-G-Y-F-D-K-L-K-G-T-L-C-S-Q-V-G-Y-A-N-S-A-V-E-N-P-S-Y-E-F-V-C-S-G-N-S-G-A-V-E-A-L-E-L-H-Y-D-E-D-L-L-P-L-R-E-I-I-G-R-F-L-S-V-I-N-P-C-A-L-N-F-Q-G-N-D-I-G-T-Q-Y-R-N-G-V-Y-F-V-Q-E-S-D-E-S-I-I-K-E-C-L-K-L-W-E-K-K-H-H-K-K-A-V-T-E-V-E-K-L-Q-N-F-Y-S-A-E-L-Y-H-Q-K-Y-L-E-K-N-A-L-G-Y-C-H-I-N-T-D-L-A-L-Q-K-W-E-E"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-D-T-F-E-S-V-K-A-V-V-V-E-Q-L-S-V-D-A-N-E-V-K-P-E-S-R-F-I-E-D-L-N-A-D-S-L-D-V-V-E-L-V-M-A-L-E-E-K-F-S-I-E-I-P-D-E-E-A-E-K-I-K-T-V-K-D-V-V-A-Y-I-E-A-N-K"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-H-P-P-S-I-T-Q-L-L-I-I-L-L-I-I-V-L-L-F-G-A-K-K-I-P-E-L-A-K-G-L-G-S-G-I-K-N-F-K-K-A-V-K-E-D-E-E-D-N-Q-S-E-E-N-T-K-S-Q-I-K-Q-S-E-S-K-N-E-N-V-S-K-T-H-T-D-S-Q-K-Q-D-T"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-S-K-G-A-V-L-I-I-S-G-P-S-G-C-G-K-S-T-L-T-K-S-L-I-E-S-I-P-N-V-Y-F-S-I-S-T-T-T-R-P-M-R-E-G-E-T-D-G-V-H-Y-H-F-V-S-K-E-H-F-L-Q-D-I-H-N-N-V-F-L-E-W-A-E-V-H-T-N-F-Y-G-T-S-L-K-P-V-Q-Q-A-L-E-Q-D-K-I-V-L-F-D-V-D-V-Q-G-H-H-S-I-K-E-Y-F-G-D-F-A-K-S-V-F-I-T-T-K-N-K-D-I-L-R-E-R-L-I-S-R-Q-T-D-D-L-Q-T-I-E-F-R-L-I-Q-A-H-N-E-M-Q-H-I-H-N-F-D-Y-L-I-I-N-D-D-I-T-T-A-K-E-A-M-V-A-I-A-R-S-L-K-Y-Q-Q-I-E-R-L-S-K-I-I-Q-K-W"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-E-E-Q-E-E-K-Q-Y-N-Q-N-I-Q-D-N-E-E-G-T-Q-M-R-E-E-L-Q-E-S-T-S-A-Q-Q-T-L-Q-E-Q-E-I-D-Y-Q-A-K-Y-L-E-L-K-D-Q-Y-V-R-A-F-A-D-F-E-N-T-K-K-R-L-E-R-D-K-N-Q-S-L-E-Y-A-Y-E-R-I-M-N-D-L-L-P-V-L-D-T-L-E-K-A-L-E-S-A-Q-S-N-P-E-A-G-A-I-A-Q-G-L-Q-L-T-L-E-G-F-L-K-V-L-S-K-H-G-V-E-V-I-A-T-D-G-E-F-D-P-N-L-H-E-C-L-M-Q-V-P-D-A-N-K-N-D-G-E-I-L-Q-T-L-Q-K-G-F-V-Y-K-H-R-V-L-R-P-S-M-V-S-V-V-K-N"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-K-Y-P-E-M-T-L-A-T-L-A-I-L-K-Y-P-N-A-L-L-R-K-K-S-I-P-V-E-I-F-D-D-N-L-H-N-F-L-D-D-M-Y-E-T-L-I-E-S-K-G-V-G-L-A-A-I-Q-V-G-R-A-E-R-I-L-I-I-N-I-P-R-E-E-D-K-Q-Q-Y-K-E-D-L-L-E-I-I-N-P-T-F-L-T-Q-E-E-C-V-E-W-E-E-G-C-L-S-V-P-D-F-Y-E-S-I-K-R-F-D-K-V-S-I-A-Y-K-D-R-Y-G-N-D-R-I-L-K-A-Q-G-F-L-A-V-A-I-Q-H-E-I-D-H-L-N-G-V-L-F-V-D-K-L-P-I-L-K-R-K-K-F-E-K-E-L-K-K-L-K-K-E-S-Q-A"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-S-Y-I-P-Y-V-I-E-R-T-G-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-D-R-I-I-L-L-S-G-E-I-N-D-H-I-A-S-S-I-V-A-Q-L-L-F-L-E-A-E-D-P-E-K-D-I-N-F-Y-I-N-S-P-G-G-V-I-T-S-A-F-S-I-Y-D-T-M-N-Y-I-H-S-D-I-S-T-I-C-I-G-Q-A-A-S-A-G-A-F-L-L-S-S-G-T-K-G-K-R-F-S-L-P-N-S-R-I-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-T-D-I-E-I-Q-A-R-E-I-L-R-L-K-K-I-L-N-E-I-M-A-H-N-T-G-Q-K-I-E-K-I-T-Q-D-T-E-R-D-F-F-M-S-G-E-E-A-K-K-Y-G-L-V-D-E-I-L-T-K-S-L-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-D-M-A-K-K-K-E-I-I-A-K-F-A-R-D-S-K-D-T-G-S-S-E-V-Q-I-A-L-L-S-Q-R-I-A-D-L-T-E-H-L-K-A-N-P-K-D-H-S-S-R-L-G-L-L-K-L-V-G-Q-R-K-S-L-L-S-Y-L-K-K-T-Q-Y-N-R-Y-A-K-L-I-G-E-L-K-L-K-D-R"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-E-K-K-K-Y-S-K-R-Y-C-R-Y-T-E-A-K-L-E-Y-I-D-Y-K-D-V-E-M-L-K-H-S-L-S-E-R-Y-K-I-M-P-R-R-L-T-G-N-T-K-R-W-Q-E-R-V-E-V-A-I-K-R-A-R-H-M-A-L-I-P-Y-I-V-D-R-K-K-V-V-E-N-P-F-K-I"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-K-F-Y-E-T-M-F-I-L-K-P-T-L-V-E-V-E-I-K-A-R-L-D-F-F-K-E-V-I-I-K-N-G-G-E-I-E-T-C-L-D-M-G-M-R-N-L-A-Y-E-I-K-K-N-K-R-G-Y-Y-F-V-I-Y-F-K-A-Q-P-S-L-I-L-E-L-E-R-N-Y-R-I-N-E-E-I-L-R-F-I-V-I-K-Y-E-S-K-K-E-Q-S-A-W-Q-S-L-V-N-K-A-N-N-K-P-E-P-K-P-T-K-A-K-K-E-D-V-A-P-E-A-K-E-Q-A-Q-T-E-A"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-V-G-L-R-G-T-I-I-R-L-E-P-M-Y-A-E-I-D-V-G-G-V-I-Y-G-M-Q-M-S-L-N-A-T-S-M-L-Q-T-K-I-D-S-Q-P-D-A-P-V-K-I-I-C-A-Q-I-I-R-E-D-A-H-L-L-F-G-F-C-E-E-I-E-K-Q-T-F-E-R-L-I-K-I-S-G-V-G-P-K-V-A-I-A-I-L-S-T-Y-T-P-T-H-F-A-K-I-I-A-D-K-D-I-E-A-L-K-K-V-P-G-I-G-V-K-G-A-A-K-I-M-V-D-I-A-G-F-F-A-Q-L-L-Q-S-Q-E-E-S-I-A-P-S-N-N-L-K-Y-E-A-S-L-A-L-Q-S-L-G-F-K-R-N-E-I-Q-K-V-L-E-H-I-E-A-L-S-V-S-E-I-V-K-E-A-L-K-R-L-A"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-E-L-T-K-I-A-T-Q-N-D-I-N-R-Q-W-I-V-L-D-A-K-D-K-V-F-G-R-L-I-T-E-I-A-T-L-L-R-G-K-H-K-P-C-F-T-P-H-I-D-C-G-D-F-V-V-I-I-N-A-T-E-V-K-F-T-G-M-K-L-K-D-K-E-Y-F-T-H-S-G-Y-F-G-S-T-K-S-K-T-L-Q-E-M-L-E-K-T-P-E-K-L-Y-H-L-A-V-R-G-M-L-P-K-N-K-L-G-R-A-M-L-K-K-L-K-V-Y-R-G-S-E-H-P-H-S-A-Q-V-A-K-S-S-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-R-V-K-T-G-V-V-R-R-R-R-H-K-K-I-L-K-L-A-R-G-F-Y-S-G-R-R-K-H-F-R-K-A-K-E-Q-L-E-R-S-M-C-Y-A-F-R-D-R-K-Q-K-K-R-D-F-R-R-L-W-I-T-R-I-N-A-A-C-K-M-N-G-V-S-Y-S-R-F-I-H-A-L-K-L-A-N-I-E-L-D-R-K-T-L-A-D-M-A-M-N-D-I-N-A-F-N-A-V-L-A-S-V-K-N-K-L-K"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-K-E-E-V-L-L-N-E-E-I-D-F-K-E-V-R-C-V-S-D-N-G-E-V-Y-G-I-I-S-S-K-E-A-L-N-L-A-H-K-A-G-L-D-L-V-L-I-S-P-N-A-K-P-P-V-C-K-I-M-D-Y-G-K-F-R-Y-Q-A-E-K-K-Q-K-E-A-R-K-K-Q-K-Q-I-E-I-K-E-I-K-L-S-T-Q-I-A-Q-N-D-I-N-Y-K-V-K-H-A-I-E-F-L-E-S-G-K-H-V-K-F-K-V-F-L-K-Q-R-E-L-N-I-P-D-A-G-M-D-T-L-G-K-V-A-V-M-L-E-D-I-A-I-A-E-K-E-P-K-L-E-G-K-H-L-N-V-L-Y-V-P-K-K-K-E-K-H"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-N-E-I-F-K-N-A-K-S-H-M-D-K-S-I-E-S-L-R-R-D-F-S-T-L-R-S-G-K-V-S-V-N-I-L-D-N-V-R-V-D-Y-Y-G-T-P-T-P-L-N-Q-V-G-S-V-I-A-Q-D-A-T-T-I-I-I-T-P-W-E-K-P-L-I-K-D-I-E-K-S-I-Q-E-A-N-I-G-V-N-P-N-S-D-S-E-C-V-K-L-F-F-P-P-M-T-Q-E-Q-R-K-E-I-A-K-N-A-R-S-M-G-E-K-A-K-V-A-I-R-N-I-R-Q-D-A-N-N-A-I-K-K-L-E-K-D-K-S-I-T-E-D-E-N-K-K-A-L-E-E-I-Q-R-Y-T-D-E-F-V-K-K-C-D-E-M-L-K-H-K-E-E-E-V-M-K-V"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-E-N-L-T-L-S-I-V-T-P-Y-G-S-I-Y-N-G-E-V-K-Y-V-V-I-P-G-S-E-G-E-F-G-V-F-P-G-H-C-N-L-L-S-L-L-K-V-G-V-I-E-F-E-N-L-E-G-N-K-G-L-V-A-I-N-W-G-H-A-Q-I-S-D-T-D-V-N-I-I-A-D-G-A-V-A-I-A-G-N-T-E-S-E-I-V-A-A-I-S-D-A-K-T-L-L-K-E-A-S-D-D-S-A-L-F-G-M-V-V-S-R-V-E-S-D-Y-K-N-F-I-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-F-N-I-I-S-K-K-Y-T-Q-A-L-V-D-S-G-S-N-L-D-E-T-L-S-I-L-K-G-L-S-L-A-L-K-D-K-R-N-A-D-I-I-A-S-P-F-L-S-K-T-Q-K-E-Q-F-L-L-E-S-V-G-K-V-D-M-K-L-Q-N-F-F-R-L-L-A-Q-S-D-R-I-L-L-I-P-Y-I-S-D-E-L-E-R-R-L-L-A-R-K-K-E-Y-A-A-T-L-T-A-K-E-S-L-D-T-K-T-L-E-K-I-Q-D-S-L-A-K-K-L-G-V-K-L-S-I-K-Q-R-L-S-E-V-D-G-I-K-L-S-V-E-D-L-G-I-E-V-S-F-S-K-E-R-F-S-N-D-L-K-H-H-I-L-K-A-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-K-I-A-F-F-V-I-C-V-G-F-P-S-L-I-F-A-S-A-S-I-Q-E-S-D-F-I-Q-R-V-I-N-F-V-I-F-V-A-I-L-W-Y-F-A-F-D-S-I-K-G-I-F-V-N-R-R-N-A-I-S-A-R-L-Q-E-V-Q-E-N-L-H-K-A-K-R-E-K-E-T-A-Q-K-R-L-E-E-S-K-E-K-A-K-N-I-V-N-A-A-K-Q-E-A-Y-L-L-E-Q-K-Y-N-D-Q-I-K-K-D-I-E-T-L-K-Y-A-L-E-S-N-I-E-F-E-R-R-K-I-T-H-E-A-V-D-E-L-L-N-K-L-I-Q-S-D-D-V-Q-L-N-K-E-D-Y-V-N-I-I-T-K-R-I-S"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-R-V-E-H-I-I-G-N-I-K-D-I-D-A-T-H-L-D-I-D-E-V-Q-I-A-W-Y-D-T-K-K-K-I-A-R-L-N-S-Q-N-G-Q-V-I-A-M-K-L-A-Q-A-P-K-Y-G-L-N-N-G-D-I-L-F-L-D-E-H-K-I-I-I-I-S-I-L-P-T-W-V-L-C-M-K-P-T-H-W-H-T-M-A-R-L-C-Y-E-I-G-N-L-H-I-P-L-F-Y-N-K-D-T-M-K-L-Q-A-P-F-E-Q-P-L-Q-R-I-L-E-K-Q-S-I-A-F-E-K-K-W-C-V-L-D-S-K-D-R-I-N-I-T-Y-P-I-A-S-E-P-K-L-I-Q-S-P-H-F-S-I-K-I-T-Q-K-G-L-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-G-K-K-V-V-G-E-L-K-L-Q-I-P-A-G-K-A-N-P-S-P-P-V-G-P-A-L-G-Q-R-S-V-N-I-M-E-F-C-K-A-F-N-E-R-T-K-D-M-G-D-F-N-I-P-V-I-I-T-I-Y-Q-D-K-S-F-T-F-I-T-K-K-P-P-V-T-D-L-I-K-K-A-A-K-I-T-K-G-S-D-N-P-L-K-N-K-V-G-K-L-T-S-K-Q-L-E-E-I-A-Q-T-K-M-E-D-L-N-A-S-D-I-E-A-A-K-K-I-V-A-G-S-A-R-S-M-G-I-E-I-Q-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-T-K-Q-E-K-I-Q-I-V-E-Y-L-S-A-E-F-K-N-A-S-A-L-I-V-C-D-Y-K-G-L-R-V-N-Q-L-E-E-L-R-C-T-S-R-S-A-N-I-K-V-Q-V-I-K-N-T-L-A-N-I-A-I-K-N-A-Q-C-P-N-L-E-L-K-D-T-N-I-F-L-W-A-D-D-Q-I-A-L-S-K-V-V-C-K-F-A-D-S-Y-N-E-H-F-S-L-K-V-G-L-F-D-K-Q-V-V-D-I-K-H-I-V-S-V-S-K-L-P-S-K-E-E-L-I-G-M-L-L-S-V-W-T-A-P-A-R-Y-F-V-T-G-L-D-N-L-R-K-Q-K-E-E-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-I-S-K-E-E-V-L-D-Y-I-G-N-L-S-V-L-E-L-S-E-L-V-K-A-F-E-E-K-F-G-V-S-A-A-P-T-V-V-A-G-A-V-A-G-G-A-G-G-G-A-A-A-E-E-K-T-D-F-N-V-V-L-V-D-A-G-A-N-K-I-N-V-I-K-A-V-R-E-I-T-G-L-G-L-K-E-A-K-D-A-T-E-Q-T-P-S-T-L-K-E-G-V-S-K-E-D-A-E-N-F-K-K-K-L-E-E-A-G-A-K-V-E-I-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-I-R-K-E-R-K-K-V-I-R-K-T-K-S-P-A-L-L-E-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-V-K-L-T-S-K-V-E-V-I-S-Y-I-P-G-E-G-H-N-L-Q-E-H-S-I-V-L-V-R-G-G-R-V-K-D-L-P-G-V-K-Y-H-I-I-R-G-A-L-D-T-A-G-V-A-K-R-N-V-S-R-S-K-Y-G-A-K-K-A-K-A-G-G-D-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-R-R-K-A-P-V-R-E-V-L-G-D-P-I-Y-N-N-K-V-V-T-K-F-I-N-K-M-M-L-D-G-K-K-S-V-S-E-K-I-I-Y-A-A-F-D-K-I-E-E-K-S-G-E-K-G-I-E-V-F-E-K-A-L-E-R-V-K-P-L-V-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-P-A-R-Q-Q-S-L-S-I-R-W-L-L-E-A-T-R-K-R-N-E-R-T-M-I-E-R-L-A-S-E-L-V-D-A-A-N-E-R-G-A-A-F-K-K-K-E-D-V-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-K-S-S-I-I-R-F-S-V-S-L-P-Q-N-L-L-E-T-L-D-E-R-L-T-H-K-G-Y-S-S-R-S-E-I-V-R-D-M-I-R-E-K-L-N-E-E-I-W-S-S-G-A-E-N-T-Q-G-V-A-V-L-T-I-I-Y-D-H-H-Q-R-E-L-N-Q-R-M-I-D-I-Q-H-T-S-T-H-K-G-N-V-E-I-L-C-N-T-H-V-H-L-D-Q-H-N-C-L-E-T-I-I-L-R-G-N-G-V-H-I-E-D-L-S-I-E-I-G-G-L-K-G-V-K-F-S-K-L-T-R-A-S-R-F-E"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-D-A-K-Q-L-G-A-M-L-G-S-M-Q-D-T-I-K-D-L-Q-E-R-N-E-Q-T-I-L-S-A-K-S-G-G-G-L-V-S-V-S-C-N-G-N-G-E-V-I-D-I-S-I-D-D-S-L-L-E-D-K-E-S-L-Q-I-L-L-M-S-A-L-N-D-V-R-K-S-V-E-D-N-R-Q-S-S-A-M-N-L-F-N-G-L-G-T-D-L-N-I-F-G-G-K-P-N-G"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Involved in the biosynthesis of the FeCO cofactor ### SEQUENCE -M-C-L-A-I-P-S-K-V-V-E-I-K-D-N-N-M-A-V-V-D-T-L-G-V-S-R-E-A-S-L-D-L-L-N-E-S-V-N-I-G-D-W-V-L-L-H-I-G-Y-V-M-S-K-I-D-E-E-S-A-R-E-S-L-R-L-Y-E-Q-I-L-Q-S-M-Q-E-E-E-N-E-R-I-E-A-N-K"} +{"text": "### FUNCTION Participates in the translocation of lipoproteins from the inner membrane to the outer membrane Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate ### SEQUENCE -M-E-V-L-R-R-Y-V-L-V-F-T-S-L-C-M-T-L-F-A-W-G-E-N-L-Q-S-I-E-A-D-F-E-Q-I-A-V-N-E-D-G-V-P-T-R-Y-E-G-H-I-I-G-K-M-P-S-K-V-K-W-D-Y-K-A-P-L-Q-K-E-I-Y-M-N-K-N-E-V-I-M-Y-E-P-R-L-E-Q-V-S-H-S-R-L-K-D-K-A-D-F-L-S-I-L-K-S-A-K-K-H-N-D-G-T-Y-H-T-K-V-D-G-I-E-Y-V-L-F-I-D-K-A-Q-K-P-E-R-I-E-F-V-D-S-M-G-V-K-T-T-L-K-L-K-N-V-K-L-N-G-A-I-S-D-K-K-F-V-F-V-P-P-Q-G-V-E-I-V-E-L-H-S-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-L-L-L-E-N-V-Q-G-L-G-K-K-G-E-I-V-E-V-K-D-G-Y-G-Q-N-F-L-I-A-K-G-K-A-Q-R-A-T-N-E-V-I-N-K-Y-K-A-Q-Q-R-K-A-E-E-L-A-A-L-E-K-A-E-M-Q-Q-M-K-K-T-I-E-S-L-T-L-T-L-H-K-K-V-G-A-N-D-T-L-F-G-S-I-T-K-E-E-I-A-L-A-L-E-E-H-K-V-S-L-D-K-K-H-I-E-I-A-Q-A-I-K-H-T-G-N-F-E-V-Q-V-K-L-G-Q-G-I-N-A-T-L-K-L-E-I-K-A-Q"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-K-V-D-H-T-K-M-P-A-P-A-V-R-L-A-K-T-M-Q-T-P-K-G-D-T-I-S-V-F-D-L-R-F-T-R-P-N-C-E-L-L-S-E-K-G-I-H-T-M-E-H-L-I-A-G-F-M-R-E-H-L-N-N-T-R-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-V-V-G-A-P-N-E-Y-N-V-K-E-A-W-E-S-S-M-R-D-V-L-R-I-C-D-E-K-D-I-P-E-L-N-I-Y-Q-C-G-T-A-K-M-H-S-L-K-E-A-Q-D-I-A-Q-V-V-L-D-K-G-V-S-V-M-N-T-Q-E-L-L-L-K-D-F-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-T-E-P-M-T-N-Y-G-Y-E-K-L-C-A-E-L-K-N-L-K-E-V-E-R-P-R-I-V-V-E-I-D-I-A-R-S-H-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-K-Q-A-F-I-E-A-R-I-N-E-L-G-L-M-L-A-N-A-Q-V-I-D-P-A-S-L-P-H-N-K-V-S-F-G-S-S-V-K-I-L-N-L-D-T-D-K-E-F-V-Y-T-L-V-G-S-M-E-S-N-P-S-K-G-L-I-S-V-S-S-P-I-A-K-A-L-M-G-K-S-E-G-D-E-V-S-I-T-L-P-N-G-E-N-E-F-E-I-L-E-V-F-Y-K-D-I-V-F-E-G"} +{"text": "### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-I-L-S-R-K-Q-D-D-S-V-I-I-G-D-D-I-E-I-K-I-I-S-I-D-K-G-S-V-R-L-G-F-S-A-P-E-N-C-V-I-L-R-G-E-L-K-E-A-I-T-S-Q-N-K-Q-A-S-Q-S-D-D-I-K-A-V-S-E-I-K-F-L-L-K-A-H-K-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-P-I-R-V-I-A-K-N-K-K-A-Y-F-D-Y-E-I-L-Q-S-L-E-S-G-I-V-L-Q-G-S-E-V-K-S-I-R-A-G-R-V-N-L-K-D-S-F-I-K-I-I-R-G-E-A-F-L-F-N-A-H-I-S-F-L-Q-T-T-Y-T-H-F-K-P-N-E-R-R-E-R-K-L-L-L-H-K-K-E-I-D-K-L-F-G-S-V-S-K-E-S-L-S-I-V-P-L-N-I-Y-F-N-Q-K-N-K-I-K-L-C-I-A-L-V-R-G-K-K-L-H-D-K-R-E-S-I-K-K-K-M-L-E-R-E-A-R-A-H-M-K-S-Y-G-K-K-L"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-A-R-L-D-T-L-K-N-K-A-E-F-D-F-V-Y-R-N-A-Q-R-F-F-H-K-D-F-V-L-Y-M-L-K-F-S-S-I-R-E-S-Y-P-L-R-Q-Q-R-I-F-Q-S-I-Q-S-R-N-A-K-L-H-L-G-L-S-V-S-R-K-I-G-K-A-Y-M-R-N-L-I-K-R-R-I-K-A-I-A-Y-E-N-C-A-D-F-K-D-V-I-F-L-I-V-V-K-E-G-I-R-E-M-D-F-A-T-L-K-N-N-L-L-A-S-F-I-K-M-Y-N-A-K-K-T-R-N-I-R-V-L-H-Q-I-S-H-Y-A-G"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-I-G-M-S-E-L-K-K-G-L-K-I-E-I-D-G-I-P-Y-R-I-T-E-Y-Q-H-V-K-P-G-K-G-A-A-F-V-R-A-K-I-K-S-F-L-D-G-K-V-I-E-K-T-F-H-A-G-D-K-C-E-E-P-N-L-Q-E-K-T-M-Q-F-L-Y-H-D-G-G-A-F-Q-F-M-D-T-T-T-Y-E-Q-I-A-L-S-D-D-Q-V-G-D-V-A-K-W-I-I-D-G-L-N-V-Q-I-L-F-H-N-E-K-A-I-S-V-D-V-P-L-V-V-E-L-T-I-T-E-T-A-P-N-F-K-G-D-T-S-S-G-G-K-K-P-A-T-L-E-T-G-A-V-V-Q-V-P-F-H-V-L-E-G-E-K-I-K-V-N-T-E-T-G-E-Y-L-E-K-V-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-N-I-I-E-G-K-L-Q-L-I-G-D-E-R-I-A-I-I-S-S-R-F-N-H-L-I-T-D-R-L-V-E-G-A-K-D-C-F-V-R-H-G-G-R-D-D-L-L-D-L-V-L-V-P-G-A-Y-E-I-P-F-A-L-Q-K-I-L-S-Q-G-E-Y-D-G-I-C-C-L-G-A-V-I-R-G-S-T-P-H-F-D-Y-V-S-A-E-A-T-K-G-I-A-N-V-T-L-K-Y-G-A-P-V-T-F-G-V-L-T-T-D-S-I-E-Q-A-I-E-R-A-G-T-K-V-G-N-K-G-F-E-A-M-A-S-L-I-E-L-I-N-L-Y-R-K-I-G-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-A-T-R-T-Q-A-R-E-A-V-I-G-M-L-Y-A-Y-D-L-G-N-E-S-I-I-E-I-A-R-S-M-L-E-E-K-K-I-K-N-K-Q-Q-D-F-A-F-S-L-L-Q-G-V-I-E-H-L-S-Q-I-D-L-C-I-A-P-Y-L-K-E-W-E-F-S-R-L-G-G-M-E-R-A-M-L-R-L-G-A-F-E-I-L-Y-T-E-T-D-T-P-V-I-I-N-E-A-V-E-L-G-K-M-Y-G-G-E-D-N-A-P-R-F-I-N-G-V-L-D-A-L-S-K-A-H-T-K-N-K-K-S-E-D-C-S-K-T-Q-D-I-I-N-D-A-L-G-K-E-S"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-F-K-N-G-G-K-Q-Y-K-V-V-E-G-S-I-I-L-L-D-K-M-S-L-E-P-K-S-K-V-E-L-N-E-V-L-A-I-V-D-G-D-K-T-D-V-G-T-P-F-V-K-G-A-K-I-E-A-E-V-I-N-E-G-R-G-K-K-V-V-T-F-K-K-R-R-R-K-D-S-K-T-K-R-G-F-R-R-D-F-T-R-V-R-I-L-K-I-V-A-K"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-I-L-K-E-F-R-E-F-A-V-K-G-N-V-M-D-M-A-V-G-V-I-I-G-G-A-F-G-K-I-V-S-S-L-V-S-D-V-I-M-P-P-I-G-W-L-I-G-G-V-D-F-K-D-L-A-I-Q-I-A-P-A-K-E-G-A-E-A-V-M-L-K-Y-G-A-F-I-Q-N-I-F-D-F-L-I-I-A-I-A-V-F-S-M-V-K-A-I-N-S-L-K-R-P-P-E-V-A-E-A-P-A-V-A-K-G-P-T-Q-E-E-L-L-A-E-I-R-D-L-L-K-K"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-Q-L-I-A-V-G-T-K-M-P-V-W-V-K-N-G-F-E-E-Y-Q-R-R-F-P-K-D-M-P-F-E-L-I-E-I-A-A-G-K-L-G-K-N-A-D-I-K-R-I-L-E-Q-E-G-K-A-M-L-A-A-A-G-K-A-K-I-V-S-L-D-I-P-G-K-P-W-T-T-E-Q-L-A-T-Q-L-E-S-W-K-S-D-G-R-D-I-C-L-L-I-G-G-P-E-G-L-S-T-E-C-K-Q-A-A-E-Q-S-W-S-L-S-P-L-T-L-P-H-P-L-V-R-V-I-V-A-E-S-L-Y-R-A-W-S-L-T-T-N-H-P-Y-H-R-E"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-T-L-A-N-I-K-S-A-K-K-R-A-V-Q-S-E-K-R-R-Q-H-N-A-S-Q-R-S-M-M-R-T-F-I-K-K-V-Y-A-A-I-A-T-G-D-K-A-A-S-Q-T-A-F-V-E-M-Q-K-V-V-D-R-M-A-S-K-G-L-I-H-A-N-K-A-A-N-H-K-A-K-L-V-A-Q-I-K-K-L-A"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-R-I-R-I-R-L-K-A-F-D-H-R-L-I-D-Q-S-T-A-E-I-V-E-T-A-K-R-A-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-R-F-T-V-L-I-S-P-H-V-N-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-L-V-D-I-V-E-P-T-E-K-T-V-D-A-L-M-R-L-D-L-A-A-G-V-D-V-Q-I-S-L-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA It is important during the early stages of 50S assembly It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-E-L-Q-V-V-G-A-N-A-L-T-V-S-E-T-T-F-G-R-E-F-N-E-A-L-I-H-Q-V-V-V-A-Y-A-A-G-A-R-Q-G-S-R-A-Q-K-T-R-A-E-V-S-G-S-G-K-K-P-W-R-Q-K-G-T-G-R-A-R-S-G-D-I-K-S-P-I-W-R-S-G-G-T-T-F-A-A-K-P-Q-D-H-S-Q-K-V-N-K-K-M-Y-R-G-A-I-K-S-I-L-S-E-L-V-R-Q-E-R-L-V-V-V-E-K-F-E-V-E-A-P-K-T-K-F-L-V-Q-K-L-K-D-L-A-L-N-D-A-L-I-I-T-A-S-L-D-E-N-L-F-L-A-A-R-N-L-Y-K-V-D-V-R-D-V-Q-G-I-D-P-V-S-L-I-A-F-D-K-V-V-I-T-T-D-A-V-K-Q-I-E-E-M-L-A"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-Q-Q-E-R-L-L-K-V-L-K-A-P-H-I-S-E-K-A-T-K-N-A-E-K-G-N-T-I-V-F-K-V-A-L-D-A-N-K-V-E-V-A-N-A-V-Q-E-L-F-E-V-K-V-D-S-V-R-T-V-V-V-K-G-K-T-K-R-H-G-A-R-M-G-R-R-S-D-W-K-K-A-Y-V-T-L-Q-E-G-Q-S-L-D-F-V-E-G-A-A-E"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-I-A-K-H-R-Y-A-R-T-S-A-Q-K-A-R-L-V-A-D-L-I-R-G-K-K-V-A-Q-A-L-E-I-L-T-F-T-N-K-K-A-S-A-L-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-D-G-A-D-V-D-D-L-K-V-A-K-I-F-V-D-E-G-P-S-M-K-R-V-M-P-R-A-K-G-R-A-D-R-I-L-K-R-T-S-H-I-T-V-V-V-S-D-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-V-H-K-G-R-N-R-G-I-A-V-G-T-E-V-S-F-G-T-F-G-L-K-A-I-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-A-V-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-V-L-Y-E-M-D-G-V-S-E-E-I-A-R-H-A-F-A-L-A-A-A-K-L-P-M-K-T-T-F-V-T-K-T-V-M"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-T-D-K-I-R-T-V-Q-G-K-V-V-S-D-K-M-D-K-S-F-V-V-A-I-E-R-T-V-K-H-P-L-Y-G-K-F-I-R-R-T-T-K-L-H-V-H-D-E-N-N-E-A-K-L-G-D-V-V-E-I-Q-E-C-R-P-V-S-K-T-K-S-H-K-L-V-R-V-V-E-K-A-V-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-E-Q-T-M-L-D-V-A-D-N-S-G-A-R-S-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-A-I-G-D-I-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-D-V-L-K-A-V-V-V-R-T-K-K-G-V-R-R-P-D-G-S-V-I-R-F-D-G-N-A-C-V-I-L-N-N-N-T-E-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-S-E-K-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-Q-N-D-E-V-I-V-L-A-G-K-D-K-N-K-R-G-K-V-T-K-V-L-P-N-G-K-V-I-V-E-G-I-N-L-I-T-K-H-E-K-P-V-P-A-L-G-K-A-G-G-L-V-K-K-E-A-A-I-D-V-S-N-V-A-I-F-N-P-T-T-N-K-A-D-R-V-G-F-R-F-E-D-N-K-K-V-R-F-F-K-S-N-N-E-I-I"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-R-D-Q-V-V-N-E-L-K-T-K-F-N-Y-S-S-V-M-Q-V-P-R-I-E-K-I-T-L-N-M-G-V-G-E-A-L-T-D-K-K-L-L-D-N-A-V-A-D-L-T-A-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-V-A-G-F-K-I-R-Q-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-E-F-F-E-R-L-I-T-I-A-V-P-R-I-R-D-F-R-G-L-S-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-Y-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-T-A-K-S-D-E-E-G-Q-A-L-L-A-V-F-N-F-P-F-R-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-I-A-R-D-V-K-R-A-K-L-A-D-K-F-Y-A-K-R-E-E-L-K-K-I-I-Y-D-I-N-S-S-D-E-D-R-W-A-A-V-L-K-L-Q-M-L-P-R-D-S-S-P-S-R-Q-R-S-R-C-R-Q-T-G-R-P-H-G-V-L-S-K-F-G-L-S-R-I-K-V-R-E-A-A-M-R-G-E-I-P-G-L-K-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-A-D-M-L-T-R-I-R-N-G-Q-A-A-N-K-V-A-I-S-M-P-S-S-K-L-K-V-A-I-A-N-V-L-A-K-E-G-Y-V-E-S-F-R-I-I-E-D-S-K-P-E-L-E-I-T-L-K-Y-F-Q-N-K-P-V-V-E-S-I-Q-R-I-S-R-P-G-I-R-I-Y-K-R-K-D-E-L-P-K-V-M-G-G-L-G-I-A-I-V-S-T-S-K-G-V-M-T-D-R-A-A-R-E-E-G-L-G-G-E-I-I-C-Y-V-A"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-N-I-P-A-G-I-E-V-K-I-N-G-Q-L-L-T-V-K-G-K-N-G-E-L-S-R-E-I-H-N-A-V-E-V-N-Q-D-A-N-A-L-T-F-V-P-R-E-G-V-A-N-A-D-A-Q-A-G-T-A-R-A-L-V-N-A-M-V-I-G-V-T-E-G-F-T-K-K-L-Q-L-V-G-V-G-Y-R-A-Q-M-K-G-N-V-V-A-L-S-L-G-Y-S-H-P-I-E-H-T-L-P-L-G-V-T-G-E-C-P-S-Q-T-E-I-I-L-K-S-A-D-K-Q-L-I-G-Q-V-A-A-D-I-R-A-Y-R-R-P-E-P-Y-K-G-K-G-V-R-Y-S-D-E-V-V-R-T-K-E-A-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-V-A-R-I-R-R-A-S-R-A-R-H-L-M-R-E-Q-G-A-T-R-L-V-V-H-R-T-P-R-H-I-Y-A-Q-V-I-A-P-N-G-S-E-V-L-A-A-A-S-T-V-E-K-V-I-K-E-Q-V-Q-Y-T-G-N-K-D-A-A-A-I-V-G-K-L-V-A-E-R-A-L-A-K-G-I-Q-V-V-A-F-D-R-S-G-F-K-Y-H-G-R-V-Q-V-L-A-D-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-N-I-E-K-Q-A-G-E-L-Q-E-K-L-I-A-V-N-R-V-S-K-T-V-K-G-G-R-I-M-S-F-T-A-L-T-V-V-G-D-G-N-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-N-M-I-N-V-A-L-N-E-G-T-L-Q-H-P-V-K-G-S-H-T-G-S-R-V-F-M-Q-P-A-S-E-G-T-G-I-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-H-N-V-L-S-K-A-Y-G-S-T-N-P-I-N-V-V-R-A-T-I-D-A-L-A-N-M-K-S-P-E-M-V-A-A-K-R-G-K-T-V-E-E-I-W-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-S-L-S-P-A-E-G-A-K-H-S-A-K-R-L-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-K-S-R-T-G-G-G-V-R-R-G-F-E-G-G-Q-M-P-L-Y-R-R-L-P-K-F-G-F-T-S-L-K-S-L-H-V-A-E-I-R-L-N-D-L-A-K-V-D-G-N-E-V-T-L-E-A-L-K-A-A-N-I-I-T-K-N-I-L-S-V-K-V-I-L-A-G-K-I-E-R-A-L-V-I-K-G-L-R-V-T-K-G-A-K-A-A-I-E-A-V-G-G-S-I-E-E"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-T-V-I-A-L-T-A-I-Y-G-I-G-K-T-R-A-K-A-I-C-V-A-T-G-I-A-E-D-V-K-I-R-E-L-S-E-E-Q-I-E-K-L-R-E-E-V-S-K-F-T-V-E-G-D-L-R-R-E-V-T-L-S-I-K-R-L-L-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-T-P-V-R-A-R-K-R-V-K-K-Q-I-A-D-G-V-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-A-W-A-T-A-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-R-C-A-E-A-V-K-E-F-G-L-K-N-L-E-V-M-V-K-G-P-G-P-G-R-E-S-T-I-R-A-L-N-A-A-G-F-R-I-T-N-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-E-Q-K-I-E-V-V-G-K-L-G-S-T-Y-G-I-R-G-W-L-R-L-Y-S-S-T-E-K-A-E-S-I-F-D-Y-Q-P-W-F-L-K-I-K-G-Q-W-Q-L-I-E-L-E-S-W-R-Y-H-S-N-D-L-I-V-K-L-K-G-T-E-D-R-E-A-A-Q-L-L-T-N-A-E-I-G-V-D-L-S-V-F-P-K-L-G-E-E-D-Y-Y-W-H-D-L-I-N-C-Q-V-V-N-L-E-N-Y-T-M-G-V-V-T-E-L-M-E-T-G-S-N-D-V-L-V-V-R-A-N-S-K-D-A-F-G-K-Q-E-R-L-I-P-F-L-Y-K-Q-V-V-K-R-V-D-L-S-T-K-T-I-T-V-D-W-D-A-G-F"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-N-I-I-K-Q-I-E-Q-E-Q-L-K-Q-N-V-P-S-F-R-P-G-D-T-L-E-V-K-V-W-V-V-E-G-S-K-R-R-L-Q-A-F-E-G-V-V-I-A-I-R-N-R-G-L-H-S-A-F-T-L-R-K-V-S-N-G-V-G-V-E-R-V-L-Q-T-H-S-P-I-I-D-S-I-F-V-K-R-K-G-A-V-R-K-A-K-L-Y-Y-L-R-E-R-S-G-K-S-A-R-I-K-E-R-L-G-N"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-I-E-E-R-V-K-K-I-I-V-D-Q-L-G-V-K-A-E-D-V-K-P-E-A-S-F-I-E-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-I-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-S-A-I-D-Y-V-A-K-A-N-A"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-E-A-A-D-K-I-G-N-R-F-D-L-I-L-T-A-A-R-R-A-R-Q-L-Q-L-H-V-R-E-P-L-V-P-E-E-N-D-K-P-T-V-I-A-L-R-E-I-E-K-G-L-I-N-G-S-I-M-D-Q-L-E-N-S-D-A-V-R-Q-E-V-A-E-Q-E-A-I-S-F-L-T-D-I-Q-T-N-A-Y-F-Y-S-F-N-D-G"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-V-Y-I-F-A-I-K-S-P-V-Y-G-G-Q-G-A-Y-L-A-Y-Q-I-A-E-E-V-L-K-A-G-H-Q-I-K-Q-I-F-F-F-Q-D-G-V-N-N-A-N-R-F-V-N-P-A-N-D-E-I-N-L-V-Q-K-W-Q-H-L-A-K-S-K-K-L-A-L-H-L-C-I-S-A-A-Q-R-R-G-I-V-D-Q-Q-T-S-T-D-S-T-N-N-L-A-D-M-F-I-L-S-G-L-G-D-F-S-R-A-V-L-T-A-D-R-L-L-T-F"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-V-L-Q-V-V-L-Y-P-D-D-R-L-T-K-V-C-E-P-V-T-Q-V-D-D-E-L-N-Q-F-I-D-D-M-F-D-T-M-Y-Q-E-G-G-I-G-L-A-A-S-Q-V-G-V-L-K-R-V-I-T-I-D-I-E-G-D-K-T-N-Q-V-V-L-I-N-P-E-I-L-E-S-C-G-E-T-G-I-E-E-G-C-L-S-I-P-G-Y-R-A-L-V-P-R-K-E-K-I-T-V-K-A-L-N-R-Q-G-E-E-V-I-Y-H-A-D-D-L-F-A-I-C-I-Q-H-E-I-D-H-L-N-G-I-V-F-V-D-H-I-S-N-L-K-R-Q-R-I-K-D-K-M-Q-K-L-K-K-Q-L-Y-R-S-K-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-Q-D-K-Q-A-I-V-A-E-V-N-E-A-A-K-G-A-L-S-A-V-V-A-D-S-R-G-V-T-V-E-K-M-T-E-L-R-K-S-A-R-E-A-G-V-T-M-R-V-V-R-N-T-L-L-R-R-A-V-E-G-T-E-F-E-C-L-T-D-T-F-T-G-P-T-L-I-A-F-S-N-E-H-P-G-A-A-A-R-L-F-T-E-F-A-K-T-N-K-E-F-E-L-K-G-A-A-F-E-G-K-V-Q-N-V-E-F-L-A-T-L-P-T-Y-E-E-A-I-A-R-L-M-G-T-M-K-E-A-A-A-G-K-L-V-R-T-F-A-A-L-R-D-K-L-Q-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-L-T-N-E-Q-I-I-E-A-I-A-S-K-S-V-S-E-I-V-E-L-I-T-A-M-E-E-K-F-G-V-S-A-A-A-A-V-A-A-A-P-A-A-A-A-A-E-E-K-T-E-F-D-V-V-L-A-N-A-G-A-N-K-V-A-V-I-K-A-V-R-G-A-T-G-L-G-L-K-E-A-K-D-L-V-E-S-A-P-A-T-L-K-E-G-I-S-K-P-E-A-E-A-L-K-K-E-L-E-D-A-G-A-Q-V-E-I-K"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-N-Q-L-D-L-I-K-S-S-I-K-S-I-P-N-Y-P-K-V-G-I-I-F-R-D-I-T-S-L-L-E-N-P-T-A-F-K-A-S-I-D-A-I-V-A-E-F-K-N-K-G-I-T-K-V-V-G-T-E-S-R-G-F-I-F-G-A-P-V-A-L-A-L-G-L-P-F-V-L-V-R-K-P-H-K-L-P-R-A-V-I-S-Q-S-Y-A-L-E-Y-G-E-D-T-L-E-M-H-L-D-S-I-N-Q-D-D-N-V-L-V-V-D-D-L-L-A-T-G-G-T-I-D-A-T-A-K-L-I-R-Q-L-G-G-Q-V-K-N-A-A-F-V-I-G-L-P-D-L-G-G-K-A-R-L-E-Q-I-G-I-K-S-F-T-L-V-E-F-D-G-H"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-H-K-K-L-Y-L-A-S-N-S-P-R-R-W-A-L-L-Q-N-L-G-L-A-L-L-P-L-A-S-E-I-D-E-T-A-H-A-N-E-M-A-Q-D-Y-C-S-R-I-A-R-E-K-N-Q-A-A-Q-A-V-R-I-R-Q-N-L-A-E-Y-P-I-L-T-A-D-I-M-V-S-I-D-G-E-I-L-G-K-P-S-H-Q-Q-Q-A-V-E-M-L-K-K-L-S-G-R-T-H-Q-V-Y-T-A-V-C-V-S-A-N-Q-Q-L-F-E-C-I-H-S-S-E-V-T-F-K-R-L-S-E-A-E-I-Y-A-Y-I-A-T-G-E-P-M-D-K-A-G-A-Y-G-I-Q-A-L-G-G-I-F-I-Q-H-L-A-G-S-F-T-G-V-M-G-L-P-I-F-E-T-V-A-L-L-K-K-V-N-I-E-V-L-P-S"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-I-L-C-K-T-D-K-R-N-S-T-I-K-P-V-K-R-V-Q-S-N-R-A-H-R-L-N-D-E-I-R-G-V-K-E-V-R-L-T-D-E-N-G-E-Q-A-G-I-V-S-I-Q-N-A-L-S-R-A-E-D-A-E-L-D-L-V-E-I-S-P-N-A-E-P-P-V-C-R-I-M-N-Y-G-K-F-I-Y-E-K-E-K-A-A-K-E-Q-K-K-K-Q-K-V-V-Q-V-K-E-I-K-F-R-P-G-T-D-E-G-D-Y-Q-I-K-L-R-N-I-L-R-F-L-E-D-G-D-K-V-K-I-T-V-R-Y-R-G-R-E-M-A-H-Q-E-I-G-L-D-V-L-E-R-V-K-T-D-T-S-E-V-A-I-V-E-S-A-P-G-K-L-E-G-R-Q-A-V-M-V-I-A-P-K-K-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-A-R-H-K-K-I-L-K-A-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-A-R-Q-N-G-L-S-Y-S-K-F-I-N-G-L-K-K-A-S-V-E-I-D-R-K-T-L-A-D-I-A-V-F-D-K-V-A-F-A-A-L-V-E-K-A-K-S-A-L"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-T-T-I-L-A-F-D-F-G-T-Y-S-I-G-C-A-V-G-Q-S-I-T-K-T-A-Q-S-L-T-A-F-K-S-Q-D-G-I-P-N-W-Q-H-I-E-K-I-I-K-E-W-Q-P-D-L-L-V-V-G-L-P-L-N-M-D-G-S-E-Q-P-L-T-Q-R-A-R-K-F-A-N-R-L-N-G-R-F-N-L-P-V-A-L-Q-D-E-R-L-T-T-T-E-A-K-S-E-I-F-S-R-G-G-Y-K-A-L-K-K-D-K-I-D-T-I-S-A-C-L-I-L-E-S-W-F-D-N-N-P"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-S-V-E-A-K-A-K-I-V-S-E-F-G-R-D-A-K-D-T-G-S-S-E-V-Q-I-A-L-L-T-A-Q-I-N-H-L-Q-T-H-F-A-T-H-K-K-D-H-H-G-R-R-G-L-L-R-M-V-S-R-R-R-K-L-L-D-Y-L-K-R-T-D-L-A-K-Y-S-E-T-I-A-R-L-G-L-R-R"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-L-S-Y-F-K-E-L-S-L-R-R-P-A-W-L-L-L-A-T-L-A-C-T-L-E-V-T-G-L-Y-F-Q-H-K-L-G-L-I-P-C-V-M-C-I-Y-E-R-V-A-L-T-G-L-L-I-A-G-L-I-A-L-I-A-P-N-F-F-L-F-R-W-L-A-L-V-L-W-G-F-S-A-F-K-G-L-S-L-S-I-K-H-Y-D-Y-Q-A-N-P-S-P-W-N-Q-C-E-F-K-P-Q-F-P-Q-T-I-P-L-D-E-W-F-P-N-I-F-A-A-G-T-V-N-C-S-E-K-Q-W-Q-M-L-G-W-G-M-P-E-W-L-I-V-A-F-S-L-F-M-L-F-F-L-I-V-F-M-S-Q-F-K-R-A-K-P-Q-Y-R-S-V-F-R"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-Q-L-L-E-F-I-P-L-I-L-F-F-A-V-Y-K-L-V-G-V-Q-A-A-A-I-T-L-V-L-A-T-I-L-Q-L-I-L-V-R-I-L-F-K-K-L-E-T-S-Q-W-I-V-G-L-S-V-I-I-F-G-I-L-T-A-Y-F-D-D-L-A-F-L-K-W-K-V-T-I-I-N-G-L-F-A-A-V-L-L-I-S-Q-Y-V-F-H-K-P-V-V-K-M-L-L-A-K-E-L-S-L-P-T-Q-V-W-N-R-L-N-L-G-W-A-I-F-F-I-I-C-M-L-I-N-I-I-I-S-Q-L-F-S-D-D-T-W-A-T-F-K-T-F-G-F-T-G-L-S-L-V-A-V-I-I-T-G-I-Y-L-Y-P-Y-I-K-K-L-E-N-N-N-E-Q-K"} +{"text": "### FUNCTION A GTPase-activating protein that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-S-R-S-K-K-T-R-R-I-S-D-I-M-P-A-R-K-A-D-K-K-P-A-L-P-I-S-N-S-K-K-R-K-P-T-R-Y-E-L-D-V-Q-A-R-E-E-K-K-K-R-K-H-K-G-L-P-T-G-S-R-N-V-I-T-E-Q-K-T-A-S-A-K-V-K-K-D-P-R-V-G-S-R-K-K-V-P-L-M-V-E-F-V-N-K-P-E-K-G-Q-M-I-K-P-V-P-L-E-P-S-N-H-A-T-K-A-T-V-S-P-E-V-E-L-T-Q-L-E-N-N-E-C-L-N-Q-L-L-D-Q-L-E-A-G-K-V-L-S-T-Q-D-Q-Q-F-V-D-E-C-L-D-R-V-H-E-L-I-I-E-L-G-I-E-D-D-E-E-N-N-E-D-L-L-L-R-Q-F-E-T-I-D-I-N-K-F-K"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-K-Q-I-P-M-T-V-R-G-A-E-L-L-R-E-E-L-E-F-L-K-N-V-R-R-P-Q-I-I-D-A-I-A-E-A-R-E-H-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-Q-Q-G-F-C-E-G-R-I-Q-E-I-E-G-K-L-G-N-A-Q-V-I-D-V-A-K-M-T-N-N-G-K-V-I-F-G-A-T-V-G-L-V-N-I-D-T-D-E-E-V-T-Y-R-I-V-G-D-D-E-A-N-I-K-E-G-L-I-S-V-N-S-P-I-A-R-G-L-V-G-K-S-V-D-D-S-V-S-I-I-T-P-G-G-K-V-E-F-D-I-I-S-V-E-Y-Q"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-E-I-K-K-D-T-Q-Q-R-M-E-K-S-L-E-A-L-K-S-H-I-S-K-I-R-T-G-R-A-Q-P-S-L-L-D-G-I-Q-V-E-Y-Y-G-S-A-T-P-L-R-Q-V-A-N-V-V-A-E-D-A-R-T-L-A-V-N-V-F-D-R-S-L-I-S-A-V-E-K-A-I-L-T-S-D-L-G-L-N-P-S-S-A-G-A-T-I-R-V-P-L-P-A-L-T-E-E-R-R-R-D-L-I-K-I-V-K-N-E-G-E-Q-G-K-I-A-I-R-N-V-R-R-D-A-N-D-Q-I-K-A-L-L-K-D-K-E-I-S-E-D-E-E-R-K-A-Q-D-E-I-Q-K-I-T-D-G-Y-V-K-K-V-D-E-V-L-M-A-K-E-K-E-L-L-D-F"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-V-A-E-T-V-K-R-D-W-Y-V-V-D-A-A-G-K-T-L-G-R-L-A-T-E-L-A-S-R-L-R-G-K-H-K-A-E-Y-T-P-H-V-D-T-G-D-Y-I-I-V-I-N-A-E-K-V-V-V-T-G-K-K-E-T-D-K-I-Y-Y-W-H-T-G-Y-V-G-G-I-K-D-A-T-F-K-E-M-I-S-R-R-P-E-A-V-I-E-I-A-V-K-G-M-L-P-K-G-P-L-G-R-D-M-F-R-K-L-K-V-Y-A-G-N-T-H-N-H-A-A-Q-Q-P-Q-V-L-D-I"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-L-T-K-V-E-F-T-A-S-L-I-S-K-Y-G-F-D-K-S-V-A-K-Q-F-V-E-Q-F-F-E-E-I-R-V-A-L-A-N-G-Q-E-V-K-L-S-G-F-G-N-F-S-L-R-K-K-N-A-R-P-G-R-N-P-K-T-G-E-S-V-A-V-S-A-R-R-V-V-V-F-K-P-G-Q-K-F-R-E-R-V-E-N-V-K-V-K-S"} +{"text": "### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-L-S-I-I-D-Q-L-E-E-K-I-K-Q-A-V-E-T-I-Q-L-L-Q-L-E-V-E-E-L-K-E-K-N-N-N-L-T-Q-E-R-D-G-L-R-Q-E-H-E-Q-L-K-V-E-Q-Q-N-F-Q-E-R-L-R-S-L-L-G-Q-I-D-N-V"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-T-L-E-Q-K-L-T-V-L-I-S-D-T-I-E-S-M-G-Y-E-L-V-G-V-E-C-Q-H-A-G-R-F-L-T-V-R-L-Y-I-D-K-E-G-G-V-T-I-D-D-C-S-D-V-S-R-Q-V-S-A-I-F-D-V-E-D-P-I-S-D-K-Y-N-L-E-V-S-S-P-G-L-D-R-P-L-F-T-L-A-H-Y-A-R-F-V-G-R-E-M-V-I-H-L-R-I-P-M-F-D-R-R-K-W-Q-G-K-L-T-K-V-D-G-D-L-I-S-L-E-I-E-N-N-G-E-H-Q-F-I-F-S-N-I-Q-K-A-N-L-I-P-V-F-D-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-R-E-F-K-R-S-D-R-V-A-Q-E-L-Q-K-E-I-A-V-I-L-Q-R-E-V-K-D-P-R-I-G-M-V-T-V-S-D-V-E-V-S-R-D-L-A-Y-A-K-I-F-V-T-F-L-F-D-N-D-Q-D-I-I-A-Q-G-M-K-G-L-E-K-A-G-P-Y-I-R-T-L-L-G-K-A-M-R-L-R-I-L-P-E-L-R-F-I-Y-D-Q-S-L-V-E-G-M-R-M-S-N-L-V-S-N-V-I-K-S-D-Q-A-K-H-K-E-D"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-Y-K-H-I-L-V-A-V-D-L-S-E-E-S-L-I-L-L-R-K-G-A-G-L-A-E-K-C-G-A-K-L-S-L-I-H-V-D-V-N-F-S-D-L-Y-T-G-L-I-D-I-N-M-S-S-V-Q-D-G-V-I-E-E-T-T-K-A-L-D-E-L-A-L-K-I-D-Y-P-V-S-Q-R-L-N-G-T-G-D-F-S-Q-V-L-E-E-A-V-A-K-Y-Q-I-D-L-L-I-T-G-H-H-Q-D-F-W-S-K-F-M-S-S-T-R-Q-V-M-N-N-V-T-V-D-M-L-V-V-P-L-I-D-E"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-S-Y-S-T-N-D-F-K-P-G-L-K-F-I-Q-D-G-E-P-C-V-I-V-E-N-E-F-V-K-P-G-K-G-Q-A-F-T-R-T-K-I-R-K-L-I-S-G-K-V-L-E-I-N-F-K-S-G-T-S-V-E-A-A-D-V-V-D-Y-N-Y-T-Y-S-Y-K-D-E-D-F-W-Y-F-M-H-P-E-T-F-E-Q-I-S-V-D-A-K-A-L-G-D-N-D-K-W-L-V-D-Q-A-E-C-I-I-T-L-W-N-G-A-A-I-S-V-T-P-P-N-F-V-E-L-A-V-V-E-T-D-P-G-L-K-G-D-T-A-G-T-G-G-K-P-A-T-L-S-T-G-A-V-V-R-V-P-L-F-V-Q-I-G-E-I-I-K-V-D-T-R-S-G-E-Y-I-S-R-V-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-N-P-I-I-D-L-Q-I-A-S-E-N-S-Q-G-L-P-S-A-Q-Q-F-S-D-W-V-K-H-A-L-T-Y-E-A-Q-T-S-N-I-P-L-T-E-L-T-I-R-I-V-D-E-A-E-S-H-H-L-N-L-T-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-V-P-E-G-I-E-L-P-L-L-G-D-L-I-I-C-R-Q-I-V-E-K-E-A-L-E-Q-K-I-S-L-D-A-H-W-A-H-L-T-I-H-G-T-L-H-L-L-G-Y-D-H-I-D-E-H-E-A-E-Q-M-E-G-L-E-S-D-I-M-Q-Q-L-G-F-Q-D-P-Y-L-A-E-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-F-C-T-A-E-E-T-K-V-I-D-S-R-L-A-A-D-G-Y-Q-I-R-R-R-R-E-C-I-G-C-K-E-R-F-T-T-F-E-S-A-E-L-A-L-P-Y-I-I-K-N-N-G-N-R-E-P-F-D-L-N-K-L-E-V-S-L-N-R-A-L-E-K-R-P-V-H-A-D-D-V-D-N-V-I-S-K-I-I-F-Q-L-K-A-L-G-E-R-E-V-P-S-K-S-V-G-H-L-A-M-D-G-L-K-Q-L-D-K-V-A-Y-I-R-F-A-S-V-Y-L-S-F-D-D-I-E-E-F-T-K-E-I-E-K-L-R-E"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-K-L-I-A-L-N-P-S-L-P-E-K-A-V-E-D-G-V-K-D-I-L-E-N-I-M-L-T-L-E-Q-A-K-R-V-E-I-R-G-F-G-S-F-S-L-H-Y-R-Q-P-R-I-G-R-N-P-K-T-G-A-S-V-K-L-D-A-K-Y-V-P-H-F-K-A-G-K-D-L-K-E-R-V-D-L-V"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-L-M-I-V-F-F-G-L-L-L-F-F-F-Q-Y-S-F-W-L-G-K-N-G-W-Q-D-Y-K-N-A-K-L-E-V-Q-R-L-T-A-E-N-I-K-L-N-A-R-N-E-L-I-A-A-E-I-D-D-L-K-N-G-V-D-A-L-E-E-R-A-R-L-D-R-E-M-V-K-S-D-E-Y-F-Y-R-I-V-P-R-N"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-K-K-P-T-Q-N-F-E-T-T-L-Q-E-L-E-S-I-V-N-H-L-E-A-G-D-L-P-L-E-Q-A-L-T-E-F-E-T-A-I-K-L-V-Q-Q-G-Q-Q-R-L-Q-Q-A-E-Q-R-I-Q-I-L-L-N-K-D-E-Q-A-E-L-A-D-Y-E"} +{"text": "### FUNCTION Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins Repression is relieved when the region becomes fully methylated ### SEQUENCE -M-K-T-I-E-V-D-D-E-L-Y-H-Y-I-A-S-R-T-Q-A-I-G-E-S-A-S-D-I-L-R-R-L-L-R-L-P-S-S-P-Q-P-F-V-L-V-Q-P-N-I-A-E-E-L-N-A-S-T-K-S-T-N-Q-A-K-K-Q-T-N-I-E-K-T-V-Q-K-F-E-R-V-L-K-S-D-T-F-V-N-E-T-K-N-V-R-R-F-L-M-L-L-S-A-L-H-I-S-D-Q-Q-G-F-A-N-A-T-A-V-V-T-G-T-E-R-T-Y-F-A-T-N-E-D-M-L-L-R-C-G-N-G-V-K-A-K-K-I-P-D-S-P-F-W-V-V-T-N-N-S-T-A-R-K-G-L-I-L-T-A-V-M-Q-S-M-Q-M-P-S-H-L-I-D-R-V-R-V-L-F-A"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-S-F-K-F-E-A-E-V-R-S-A-Q-G-K-G-A-S-R-R-L-R-H-N-G-Q-V-P-A-I-I-Y-G-G-N-A-E-P-V-S-I-I-L-D-H-D-K-V-N-N-V-Q-I-H-D-A-F-Y-N-E-V-L-T-I-V-L-A-E-K-E-V-Q-V-K-V-Q-A-I-Q-R-H-P-T-K-P-K-L-L-H-L-D-F-K-R-V"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-Q-I-T-K-T-A-V-A-G-T-L-E-S-S-D-V-Q-I-R-I-A-P-S-T-T-M-D-I-E-I-N-S-S-V-A-K-Q-F-G-E-D-I-L-N-S-V-T-A-V-L-A-Q-F-E-V-S-S-A-Q-I-I-I-E-D-K-G-A-L-D-C-V-L-R-A-R-L-K-A-A-L-L-R-A-T-D-E-A-L-A-W-E-K-I-L"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-E-K-I-I-I-D-T-E-Q-F-Q-R-T-I-S-R-I-S-H-Q-I-I-E-K-H-A-I-L-D-N-I-I-L-V-G-I-K-R-R-G-A-E-I-A-E-M-L-Q-K-R-I-S-E-L-A-Q-I-S-L-P-L-M-A-L-D-I-T-F-Y-R-D-D-L-N-L-T-S-K-D-P-V-Y-T-G-V-E-H-Q-L-N-I-E-G-K-T-V-I-L-I-D-D-V-L-F-T-G-R-T-I-R-A-A-L-D-A-L-L-D-F-G-R-A-K-R-I-E-L-V-I-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-A-L-N-E-Q-V-Q-V-R-T-E-H-Y-D-G-V-S-Q-V-A-L-I-H-S-T-N-G"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-A-K-S-N-Y-I-T-R-A-G-W-Q-A-L-D-Q-E-L-K-Y-L-W-K-E-E-R-P-K-V-T-Q-S-V-S-E-A-A-A-L-G-D-R-S-E-N-A-E-Y-I-Y-G-K-R-R-L-R-E-I-D-R-R-I-R-F-L-S-K-R-L-E-A-L-Q-I-I-D-Y-H-P-Q-Q-A-G-K-V-F-F-G-A-W-I-E-L-E-N-N-E-G-E-I-N-Q-Y-R-I-V-G-C-D-E-F-D-P-T-K-N-W-I-S-I-D-S-P-V-A-R-A-L-I-G-K-C-V-D-D-E-I-E-V-Q-T-P-T-G-K-A-V-F-Y-I-N-K-I-W-Y-D-T-K-S-L-Y"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-P-K-V-P-S-N-T-I-A-L-N-K-R-A-R-H-E-Y-F-I-E-D-E-I-E-A-G-L-A-L-Q-G-W-E-V-K-S-L-R-A-G-K-A-N-I-G-D-S-Y-V-T-F-R-H-G-E-A-F-L-F-G-A-T-I-T-P-L-N-M-A-S-T-H-I-V-A-D-P-T-R-T-R-K-L-L-L-N-Q-R-E-L-D-S-L-F-G-K-V-N-R-D-G-M-T-V-V-A-L-S-L-Y-W-K-N-A-W-A-K-V-K-I-G-L-A-K-G-K-K-L-H-D-K-R-E-D-I-K-D-R-E-W-H-V-T-K-Q-R-I-M-K-N-A-G-R-G-S"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-L-H-T-I-V-N-C-P-T-C-A-K-Q-V-I-W-D-P-V-S-K-Y-R-P-F-C-S-E-R-C-Q-L-I-D-L-G-E-W-A-N-E-E-K-R-I-A-S-V-E-D-E-A-M-H-Y-T-F-E-N-N-D"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-R-N-P-F-S-L-F-N-L-P-V-Q-F-Q-I-D-N-A-Q-L-S-E-R-Y-L-A-L-Q-K-Q-F-H-P-D-N-F-A-N-E-S-A-D-K-Q-L-A-A-L-Q-Q-S-A-D-V-N-E-A-L-Q-I-L-K-D-P-I-A-R-A-T-A-I-I-E-I-N-T-G-I-V-K-N-L-E-E-N-S-R-Q-D-L-D-F-L-M-Q-H-M-E-W-H-E-K-L-D-S-I-E-N-S-R-S-E-Q-Q-L-A-G-F-L-K-Q-I-K-T-E-Q-R-N-V-E-Q-Q-L-A-T-L-L-N-Q-Q-Q-W-Q-K-A-D-L-L-T-E-R-L-R-Y-F-K-K-L-I-I-Q-I-E-K-V-E-E-K-L-L-E-Y"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-T-E-K-E-T-A-T-P-A-D-V-E-V-A-S-Q-E-E-Q-I-D-Q-T-T-E-A-Q-V-E-E-P-S-I-E-A-E-L-A-G-C-Y-A-K-I-H-E-L-E-T-Y-I-A-E-A-D-K-R-E-Q-D-I-Q-L-R-A-Q-A-E-I-Q-N-I-R-R-R-T-E-Q-D-I-E-K-A-H-K-F-A-L-E-K-F-A-K-E-L-L-T-V-V-D-N-L-E-R-G-L-V-A-L-D-T-A-V-T-D-E-K-T-Q-A-L-V-D-G-V-E-M-T-H-K-E-F-V-S-T-L-A-K-F-G-I-E-A-I-G-E-I-G-D-V-F-N-P-E-L-H-Q-A-I-S-M-Q-P-A-E-N-I-E-A-N-H-L-S-Q-V-L-Q-K-G-Y-T-L-Q-G-R-V-I-R-P-A-M-V-M-V-A-A"} +{"text": "### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-K-G-I-Q-I-T-E-S-S-N-N-N-L-V-N-S-F-W-L-L-D-E-E-K-N-E-A-R-C-I-A-A-K-G-D-V-Y-Q-E-D-Q-V-I-A-I-N-E-L-G-Q-I-A-Y-R-E-I-P-V-N-I-A-P-T-I-K-V-E-G-G-Q-H-L-N-V-N-V-L-R-R-E-T-L-E-D-A-I-K-N-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-T-R-T-F-T-E-S-L"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-D-K-V-A-H-L-G-T-V-G-D-Q-V-T-V-K-S-G-Y-A-R-N-F-L-I-P-Q-G-K-A-V-M-A-T-A-A-N-I-A-H-F-E-A-R-R-A-E-L-E-A-K-A-A-A-V-L-S-A-A-K-E-R-A-A-K-I-A-A-I-G-A-V-S-V-S-A-T-A-G-D-D-G-R-L-F-G-S-I-S-A-K-D-I-A-D-A-L-V-A-A-G-I-E-V-T-K-S-E-V-R-L-G-E-G-P-L-R-T-T-G-E-H-E-V-K-V-H-L-H-A-E-V-N-A-M-V-T-V-N-V-V-A-E"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-N-Q-R-K-P-A-N-N-S-L-I-D-N-C-L-T-L-T-G-I-V-T-S-I-V-K-Q-S-Q-S-P-L-G-I-P-N-Y-S-F-W-L-E-H-R-S-N-K-M-E-V-N-L-E-R-Q-V-W-C-K-I-Q-V-I-L-N-G-C-Q-F-S-L-I-T-Q-Q-I-K-L-G-D-K-V-K-I-S-G-F-I-H-T-H-K-D-Y-N-G-L-S-K-L-V-L-H-T-E-Q-I-E-F-I-D-Q-E-K-P-N-G-T-L-F-P-S-S"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-P-A-M-I-E-R-Y-T-A-S-V-T-E-A-G-G-Q-V-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-V-L-M-N-V-E-A-P-K-S-V-I-D-E-L-E-T-N-F-R-Y-N-D-A-V-L-R-N-L-I-V-H-T-K-A-A-V-K-E-A-S-L-M-A-K-A-K-E-S-K-T-T-E-V-V-A-E-V-E-S-K-E-A-S-E"} +{"text": "### FUNCTION RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities ### SEQUENCE -M-S-V-Q-P-E-T-M-P-D-S-S-N-K-T-N-P-T-V-K-E-V-I-A-Y-L-A-D-K-F-P-L-C-F-S-I-E-G-E-A-K-P-L-K-V-G-L-S-Q-D-L-A-E-A-L-A-D-D-E-K-V-S-K-T-L-L-R-Q-V-L-R-S-Y-T-M-S-W-R-Y-L-A-C-C-K-A-N-A-Q-R-I-G-L-Q-G-E-N-V-G-I-V-D-E-A-Q-A-E-H-A-A-Q-S-L-A-V-A-K-E-A-Y-A-A-R-K-A-E-Q-R-K-E-Q-R-K-D-F-F-K-K-K-A-R-E-E-R-N-A-K-T-M-N-K-A-V-K-K-G-S-P-K-K-D-T-F-A-K-A-T-A-E-S-L-A-V-L-T-H-K-F-S-K-G-N-K"} +{"text": "### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-S-A-N-Y-I-E-V-Q-I-F-G-Q-V-L-R-L-H-C-P-A-E-Q-Q-E-N-L-R-A-S-A-Q-R-L-E-E-R-V-A-L-L-K-D-Q-S-G-I-I-Q-L-E-K-V-L-A-I-V-A-L-N-L-N-Y-E-L-E-Q-E-K-Q-K-N-A-D-N-K-T-V-L-E-S-C-I-H-Q-L-D-S-S-L-N-K-L-A-T-T-G-S-I-A-I-N-Q-E-N-I"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-Q-I-K-L-I-V-G-L-A-N-P-G-A-K-Y-E-G-T-R-H-N-A-G-E-W-L-V-N-E-L-A-R-M-Y-N-T-S-L-K-D-E-A-K-Y-F-G-K-T-A-K-I-N-T-V-N-G-D-V-W-L-L-I-P-T-T-F-M-N-L-S-G-K-A-V-G-A-L-A-H-F-F-R-I-K-A-E-E-I-L-I-A-H-D-E-L-D-L-P-P-G-V-A-K-L-K-Q-G-G-G-H-G-G-H-N-G-L-K-D-I-I-S-A-L-G-N-N-N-N-F-Y-R-I-R-L-G-I-G-H-P-G-H-K-D-Q-V-A-G-Y-V-L-S-K-P-A-P-Q-D-Q-Q-K-I-N-A-V-I-D-E-A-S-R-C-L-E-I-L-F-K-D-G-V-T-S-A-T-N-R-L-N-S-F-K-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-K-L-T-F-S-R-E-L-R-L-L-A-P-I-Q-F-K-A-V-F-E-Q-P-Y-R-A-S-T-A-E-L-T-I-L-A-R-Q-N-C-V-N-T-P-R-L-G-L-T-V-A-K-K-H-L-K-R-A-H-D-R-N-R-I-K-R-I-V-R-E-S-F-R-L-K-Q-H-Q-L-P-N-F-D-F-V-F-V-A-K-H-G-I-G-K-L-D-N-A-T-L-F-A-T-I-D-K-L-W-T-R-H-I-R-L-S-Q-Q-A-Q-S-K-N"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-Y-L-N-A-L-R-R-E-R-I-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-F-I-I-L-L-K-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-S-I-S-H-N-N-N-G-S-S-Q-A-Q-A-P-Q-Q-A-V-Q-T-T-Q-P-V-E-A-I-V-A-T-D-K-M-E"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-M-K-H-I-D-L-K-I-L-D-N-R-I-G-R-E-F-P-L-P-T-Y-A-T-T-G-S-A-G-L-D-L-R-A-L-I-D-S-A-I-T-V-E-A-G-Q-T-V-L-I-P-T-G-I-S-V-Y-I-A-D-P-N-L-A-A-V-I-L-P-R-S-G-L-G-H-K-N-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-P-L-M-V-S-I-W-N-R-S-D-K-P-F-T-I-E-V-G-D-R-I-A-Q-L-V-F-V-P-V-V-Q-A-S-F-N-I-V-T-D-F-E-Q-T-S-R-G-E-G-G-F-G-H-S-G-K-Q"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-I-S-I-W-Q-L-L-I-I-V-A-I-I-V-L-L-F-G-T-K-K-L-R-T-L-G-T-D-L-G-E-S-V-K-G-F-K-K-A-M-A-E-D-K-S-Q-D-A-N-F-D-K-V-E-A-K-E-S-T-S-T-T-E-K-T-K-E-K-E-Q-A"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-S-E-L-I-L-I-F-V-V-G-L-V-V-L-G-P-Q-R-L-P-V-A-I-R-T-V-M-G-W-V-R-T-I-R-S-L-A-T-N-V-Q-H-E-L-A-Q-E-L-K-L-Q-E-L-Q-E-S-I-K-K-A-E-A-M-N-L-T-T-L-S-P-E-L-T-Q-T-V-E-D-L-K-Q-S-A-Q-K-M-Q-N-D-L-N-N-A-N-Q-I-G-K-L-T-D-E-Q-V-A-D-I-Q-Q-N-I-A-N-A-Q-P-S-E-I-T-E-A-N-E-L-D-E-S-K-L-T-A-Y-Y-P-P-D-D-D-L-V-S-P-S-T-T-K-L-E-Q-D-K-Q-N-V-N"} +{"text": "### FUNCTION This regulatory protein, when combined with SAM represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-I-N-W-S-G-K-Y-I-S-P-Y-A-E-H-G-K-K-S-K-Q-V-K-K-I-T-V-S-I-P-I-K-V-L-E-I-L-T-N-E-R-T-R-R-Q-I-N-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-F-T-G-Q-P-L-P-A-D-E-D-L-M-K-E-R-Y-D-E-I-P-E-K-A-K-S-R-M-R-D-L-G-I-D-P-D-E-W-Q-Y"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-E-E-N-Q-V-A-A-T-E-A-E-E-Q-T-P-F-E-L-Q-I-Q-R-I-Y-I-K-D-V-S-F-E-A-P-N-L-P-T-I-F-H-Q-E-W-K-P-Q-L-G-F-E-L-D-T-E-T-V-K-L-A-D-D-L-Y-E-V-I-L-H-I-N-V-S-T-T-L-E-D-S-G-D-T-A-F-I-C-E-V-K-Q-A-G-V-F-T-I-K-G-L-E-G-I-Q-L-A-H-C-L-A-S-Q-C-P-S-V-L-Y-P-Y-A-R-E-L-I-A-S-L-V-N-R-G-T-F-P-A-L-N-L-S-P-V-N-F-D-A-L-F-V-D-Y-L-Q-R-Q-E-Q-E-A-A-E-A-E-E-E-T-P-A-P-A-S-N"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-N-K-L-A-N-Q-H-L-I-W-I-D-L-E-M-T-G-L-D-P-N-Q-D-R-I-I-E-I-A-T-I-V-T-D-K-D-L-N-I-L-A-K-G-P-V-L-A-V-H-Q-P-N-T-L-L-S-K-M-N-E-W-C-I-K-T-H-T-A-N-G-L-I-E-R-V-K-Q-S-K-L-T-E-R-A-A-E-L-Q-T-L-D-F-L-K-Q-W-V-M-K-G-S-S-P-I-C-G-N-S-V-A-Q-D-K-R-F-L-Y-Q-Y-M-P-D-L-A-D-Y-F-H-Y-R-H-L-D-V-S-T-L-K-E-L-A-R-R-W-K-P-E-I-L-Q-Q-F-S-K-K-N-S-H-L-A-L-D-D-I-R-E-S-I-E-E-L-K-F-Y-R-E-H-F-I-K-L-A"} +{"text": "### FUNCTION Activates ribosomal RNA transcription Plays a direct role in upstream activation of rRNA promoters ### SEQUENCE -M-L-E-Q-Q-P-A-Q-N-P-L-T-V-S-M-L-N-A-Q-A-Q-Q-V-N-K-P-L-R-D-N-V-K-A-A-L-K-N-Y-L-S-Q-L-N-G-E-D-P-T-E-L-Y-E-L-V-L-S-E-I-E-H-P-M-L-D-M-V-M-Q-Y-T-R-G-N-Q-T-R-A-A-T-M-L-G-I-N-R-G-T-L-R-K-K-L-K-K-Y-G-M-G"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-V-S-P-R-R-R-A-R-E-C-A-V-Q-A-L-Y-S-W-Y-I-S-Q-N-S-I-E-E-V-E-L-A-F-V-T-D-Q-D-M-K-G-V-D-L-P-Y-F-R-K-L-L-R-G-T-A-L-Y-V-E-A-I-D-H-D-I-R-P-Y-L-D-R-M-E-N-D-V-D-P-I-E-R-T-I-L-R-L-A-T-Y-E-L-K-Y-E-L-D-V-P-Y-K-V-V-I-N-E-G-I-E-V-A-K-V-F-G-S-D-D-S-H-K-Y-I-N-G-I-L-D-K-L-A-P-A-L-G-R-K"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-P-K-Y-T-A-V-N-Y-L-I-Y-L-L-S-K-R-D-Y-S-E-Y-D-L-R-N-K-L-I-Q-K-Q-Y-D-T-D-E-I-E-H-A-I-Q-Q-A-Q-L-N-N-W-Q-N-D-E-R-Y-C-A-S-F-I-R-Y-R-S-Q-Q-G-I-G-P-R-R-L-K-Q-E-L-R-L-K-G-I-K-D-Y-L-I-S-E-Q-L-Q-N-T-E-I-D-W-F-S-L-A-E-L-L-F-E-K-K-R-P-L-D-W-N-I-K-V-K-Q-K-M-W-R-F-M-L-S-R-G-F-Y-N-E-H-F-S-H-L-M-D-L-E-E-V-S-K-E-Y-E"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-V-D-Y-I-L-L-V-I-S-T-A-L-I-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-V-E-T-A-I-G-M-G-M-A-T-T-F-V-L-T-L-A-S-L-S-A-Y-L-V-E-R-F-I-L-I-P-L-D-A-Q-F-L-R-T-L-V-F-I-L-V-I-A-V-I-V-Q-L-T-E-M-I-V-H-K-T-S-P-T-L-Y-R-L-L-G-I-Y-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-V-N-L-S-N-N-L-I-E-S-V-L-Y-G-F-G-A-A-V-G-F-S-L-V-L-V-L-F-A-A-L-R-E-R-L-A-A-A-D-V-P-R-P-F-Q-G-A-S-I-A-L-I-T-A-G-L-M-S-L-A-F-M-G-F-T-G-L-V-K-L"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-E-Q-Q-E-I-I-H-I-S-I-S-E-A-A-Q-A-H-F-R-C-L-L-E-Q-Q-E-P-N-T-H-I-R-I-F-V-V-N-P-G-T-P-S-A-E-C-G-V-S-Y-C-P-S-N-A-V-E-E-T-D-T-E-F-K-F-T-G-F-S-A-F-V-D-E-L-S-L-P-F-L-A-D-A-E-I-D-Y-V-T-D-Q-M-G-A-Q-L-T-L-K-A-P-N-S-K-M-R-K-I-A-D-D-A-P-F-I-E-R-L-D-Y-V-I-Q-T-Q-V-N-P-Q-L-A-S-H-G-G-Q-V-T-L-I-E-V-T-E-D-K-Y-A-I-L-Q-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-E-G-I-E-K-Q-L-L-A-T-F-P-T-E-L-K-G-V-K-D-V-T-E-H-Q-R-G-E-H-S-Y-Y"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-K-V-D-H-T-R-M-N-A-P-A-V-R-V-A-K-T-I-T-T-P-K-G-D-L-I-T-V-F-D-L-R-F-C-R-P-N-M-E-I-M-S-S-K-G-I-H-T-L-E-H-L-Y-A-G-F-M-R-D-H-L-N-S-D-K-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-E-P-S-A-Q-A-V-A-N-A-W-K-N-A-M-H-D-I-L-T-K-V-S-D-V-T-Q-I-P-E-L-N-I-Y-Q-C-G-T-F-S-E-H-S-L-E-D-A-H-Q-I-A-R-D-V-L-A-K-G-I-S-V-N-L-N-E-D-L-T-L-D-E-E-W-L-N-R"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-D-C-I-E-M-Q-G-T-I-L-E-T-L-P-N-T-M-F-R-V-E-L-E-N-G-H-I-V-A-A-H-I-S-G-K-M-R-K-N-Y-I-R-I-L-T-G-D-K-V-T-V-E-M-T-P-Y-D-L-S-K-A-R-I-I-F-R-A-R"} +{"text": "### FUNCTION Globally modulates RNA abundance by binding to RNase E and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome ### SEQUENCE -M-Y-D-L-T-A-L-R-Q-Q-T-D-E-I-I-D-N-L-L-K-D-G-S-D-P-E-A-L-H-I-I-E-H-H-I-A-H-H-D-F-D-K-L-E-K-L-V-V-D-A-Y-K-L-G-Y-E-I-S-E-A-E-E-I-E-D-D-Q-G-N-V-L-F-V-C-D-I-V-S-E-V-K-L-N-G-D-I-I-T-A-Q-Q-Q-E-L-L-P-L-I-E-K-A-A-A-E-Y-E-G-W-G-T-Y-F-E-D-P-N-A-E-E-D-E-Y-G-D-D-G-E-F-F-D-D-E-D-E-A-D-F-N-N-A-K-V-H"} +{"text": "### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-T-D-L-P-V-D-K-I-L-D-T-L-G-L-R-C-P-E-P-V-M-L-T-R-K-T-I-R-H-M-Q-Q-G-E-I-L-F-I-L-A-D-D-P-A-T-T-R-D-I-P-S-F-C-E-F-M-D-H-Q-L-L-K-S-K-T-D-T-P-P-Y-E-Y-W-I-K-K-G-I"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-A-A-I-F-T-E-I-S-P-T-T-A-W-Q-L-V-K-H-E-N-A-F-L-A-D-I-R-A-L-A-H-Y-L-D-D-H-P-S-G-A-F-H-L-T-N-D-S-Y-A-E-F-L-D-L-V-S-D-E-Q-A-V-I-V-V-C-Y-H-G-I-S-S-R-S-V-A-Q-F-L-V-E-Q-G-F-E-T-V-Y-S-V-T-G-G-F-E-A-W-Q-K-L-A-L-P-V-T-K-G-C-D-Q"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-G-G-L-G-N-L-M-K-Q-A-Q-Q-M-Q-E-R-M-Q-K-M-Q-E-E-I-A-Q-L-E-V-T-G-E-S-G-A-G-L-V-K-V-T-I-N-G-A-H-N-C-R-R-I-E-I-D-A-S-L-M-E-D-D-K-E-M-V-E-D-L-V-A-A-A-F-N-D-A-V-R-R-A-E-D-L-Q-K-E-K-M-A-S-V-T-S-G-M-Q-L-P-P-G-M-K-L-P-F"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-E-K-L-D-R-L-S-E-A-F-K-M-L-L-K-Q-E-K-C-S-S-Q-S-E-I-V-T-A-L-Q-A-L-G-F-K-N-I-N-Q-S-K-V-S-R-M-L-S-K-F-G-A-I-R-T-R-N-T-K-M-E-M-V-Y-Q-L-P-T-E-L-S-I-P-T-T-S-S-P-L-K-N-L-V-L-D-I-D-Y-N-E-V-L-I-V-V-K-T-S-P-G-A-A-Q-L-I-A-R-L-L-D-S-M-G-K-S-E-G-I-L-G-T-I-A-G-D-D-A-I-F-I-T-P-T-H-S-T-P-M-E-T-L-I-K-N-I-T-T-L-F-E-S-S-F"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-A-V-I-P-M-V-V-E-Q-T-S-K-G-E-R-S-Y-D-I-Y-S-R-L-L-K-E-R-I-I-F-L-N-G-E-V-E-D-H-M-A-N-L-I-V-A-Q-L-L-F-L-E-A-E-D-P-E-K-D-I-Y-L-Y-I-N-S-P-G-G-V-V-T-A-G-L-A-I-Y-D-T-M-N-F-I-K-P-D-V-A-T-L-C-T-G-Q-A-C-S-M-G-A-F-L-L-S-G-G-K-K-G-K-R-F-A-L-P-N-A-R-V-M-I-H-Q-P-L-G-G-A-R-G-Q-A-T-D-I-Q-I-Q-A-Q-E-I-L-K-L-K-E-M-L-T-R-K-M-A-E-H-S-G-Q-T-F-A-K-V-A-A-D-T-E-R-D-N-F-M-S-A-T-E-A-K-N-Y-G-L-I-D-K-V-L-T-S-R-G-E-V-A"} +{"text": "### FUNCTION Acetylates the N-terminal alanine of ribosomal protein bS18 ### SEQUENCE -M-I-E-T-I-V-E-Q-D-F-N-R-L-F-E-I-E-Q-A-A-H-L-V-P-W-S-K-G-T-L-L-N-N-Q-G-A-K-Y-L-N-L-K-Y-T-E-Q-D-N-I-I-A-F-A-I-C-Q-T-L-L-D-E-A-T-L-F-N-L-A-V-D-P-A-F-Q-A-Q-G-Y-A-K-K-L-L-T-A-L-I-N-Q-L-Q-A-R-G-I-S-T-L-W-L-E-V-R-Q-S-N-T-I-A-Q-K-L-Y-D-S-V-G-F-N-Q-I-T-I-R-K-N-Y-Y-P-M-P-D-G-S-R-E-N-A-V-I-M-A-L-Y-L"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-F-Q-S-G-G-K-Q-H-R-V-S-E-G-Q-V-V-R-L-E-K-L-E-L-A-T-G-E-K-V-E-F-D-S-V-L-M-V-V-N-G-E-D-I-K-I-G-A-P-V-V-A-G-A-K-V-M-A-E-V-V-A-Q-G-R-G-D-K-I-K-I-V-K-F-R-R-R-K-H-S-R-K-Q-Q-G-H-R-Q-W-F-T-E-V-K-I-T-G-I-Q-A"} +{"text": "### FUNCTION Required for spatial organization of the terminus region of the chromosome during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-R-Y-Q-K-L-E-I-Q-E-A-N-W-Q-W-K-Y-L-L-K-K-H-R-E-G-E-N-I-T-K-H-T-E-Q-S-L-I-E-L-K-V-Q-F-L-T-T-L-Q-H-S-P-A-E-I-E-Q-W-I-K-A-E-M-T-A-E-Q-R-K-R-M-R-Q-S-I-R-A-K-R-K-R-F-F-N-A-E-K-L-T-T-K-K-K-S-I-D-L-D-Y-A-S-W-L-R-L-S-K-Y-S-K-T-H-A-M-T-L-S-E-T-I-N-H-L-I-D-E-R-E-N-Q-H-L-Y-S-E-Q-M-A-K-M-K-A-S-L-K-D-L-L-K"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-F-D-G-Y-R-P-N-V-G-I-V-I-C-N-K-V-G-Q-V-L-W-A-R-R-F-G-Q-N-S-W-Q-F-P-Q-G-G-I-N-E-G-E-N-I-E-T-A-M-Y-R-E-L-Y-E-E-V-G-L-T-K-K-D-V-R-L-L-W-A-S-K-Y-W-L-K-Y-K-L-P-K-R-L-V-R-N-D-A-S-Q-P-V-C-I-G-Q-K-Q-R-W-F-L-L-Q-L-V-S-D-E-S-A-V-N-L-K-T-T-K-S-P-E-F-D-G-W-R-W-V-S-F-W-Y-P-V-R-Q-V-V-S-F-K-R-D-V-Y-R-K-V-M-R-E-F-A-A-I-L-L-N-E-T-R-K-G-E-T-E-R-S-V-L-E-A-S-D-K-R-E-Y-Q-R-R-E-T-R-K-S-A-R-A-W-N-H-Y-P-K-G-K"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-M-N-M-L-L-V-S-L-G-A-V-A-G-A-I-L-R-W-Q-L-A-V-W-F-N-P-F-L-T-Q-F-A-F-G-T-L-F-V-N-L-C-G-C-F-L-I-G-I-T-L-G-V-N-L-Q-D-A-Q-K-L-L-F-V-T-G-F-L-G-S-F-T-T-F-S-S-F-S-A-E-V-S-Q-F-I-L-S-E-K-Y-W-R-G-L-A-V-I-S-A-H-L-I-G-G-L-V-L-T-I-L-G-I-L-V-A-K-F-W-V-S-G-R-F-Y"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-S-Q-F-E-L-R-I-V-S-A-E-K-Q-I-F-N-G-Q-V-V-S-V-R-V-S-G-V-E-G-E-L-G-I-Y-A-G-H-T-P-L-L-T-A-I-K-P-G-M-V-K-Y-T-L-E-D-N-K-E-E-F-I-Y-V-S-G-G-F-L-E-V-Q-P-T-I-V-T-V-L-A-D-I-A-I-R-G-E-E-L-D-Q-Q-R-I-I-A-A-K-R-K-A-E-D-T-L-S-K-T-N-N-A-E-L-S-A-K-L-A-R-E-I-A-K-L-R-V-Y-E-I-V-N-S-K-L-T-K-K-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-E-L-S-T-V-A-R-P-Y-A-K-A-A-F-D-F-A-L-E-Q-G-Q-L-D-K-W-Q-E-M-L-Q-F-S-A-L-V-A-E-N-E-Q-V-V-E-Y-I-T-S-S-L-A-S-G-Q-I-S-E-I-F-L-Q-I-C-D-D-Q-L-D-Q-Y-G-Q-N-F-I-R-V-M-A-E-N-K-R-L-A-I-L-P-E-V-F-N-R-F-N-A-L-R-A-E-Y-E-A-I-K-K-V-I-V-V-S-A-T-E-L-S-Q-A-Q-E-E-K-I-A-K-A-M-E-K-R-L-G-Q-K-V-R-L-T-T-E-I-D-S-T-L-L-T-G-I-I-I-K-Y-D-D-I-V-I-D-G-S-S-R-G-Q-L-N-R-L-T-Q-A-L-S-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-L-N-A-T-L-I-G-Q-L-I-A-F-A-L-F-V-A-F-C-M-K-Y-V-W-P-P-L-I-K-A-I-E-E-R-Q-A-N-I-A-N-A-L-S-S-A-E-K-A-K-Q-E-Q-A-D-S-K-V-L-A-E-Q-E-I-I-K-A-K-E-E-A-Q-K-I-I-D-L-A-T-K-R-R-N-E-I-L-E-S-V-Q-A-D-A-E-V-E-R-Q-R-I-I-E-Q-G-H-A-E-I-D-S-E-R-K-R-V-Q-E-E-L-R-Q-K-V-A-A-L-A-V-A-G-A-E-R-I-V-G-R-S-V-D-T-A-A-N-N-D-I-I-D-K-L-V-A-E-L"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-I-L-Q-M-L-Y-Y-P-D-Q-R-L-R-K-I-A-R-S-V-S-I-I-S-H-D-T-K-K-I-I-S-D-M-F-E-T-M-Y-F-Q-Q-G-I-G-L-A-A-T-Q-V-D-I-H-Q-K-I-I-V-I-D-L-N-N-N-I-Q-K-R-L-V-F-I-N-P-C-I-I-K-K-I-G-T-I-T-H-I-I-E-G-C-L-S-I-P-K-I-R-A-S-V-P-R-S-Q-N-I-I-V-Q-S-L-D-E-N-G-N-N-F-E-M-E-A-T-D-L-L-S-V-C-I-Q-H-E-I-D-H-L-L-G-K-L-F-I-D-Y-L-S-P-F-K-I-Q-R-I-H-K-K-I-N-K-W-S-T-V-Y-K-N-H-I-K-L-S-H"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-I-K-S-S-S-L-R-L-R-K-R-I-K-K-Q-V-T-D-G-I-A-H-I-H-A-S-F-N-N-T-I-V-T-I-S-D-R-Q-G-N-T-L-G-W-A-T-S-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-I-A-A-E-R-C-A-E-I-V-Q-E-Y-G-V-K-N-L-E-V-M-V-K-G-P-G-P-G-R-E-S-A-V-R-A-L-N-A-A-G-F-H-I-I-S-I-I-D-V-T-P-I-P-H-N-G-C-R-P-A-K-K-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-V-R-I-A-G-V-N-V-P-D-R-K-H-A-V-I-A-L-M-S-I-Y-G-I-G-R-S-R-A-K-L-I-C-L-S-I-G-V-D-E-Y-T-K-I-G-Q-L-S-D-V-Y-I-D-K-M-R-N-E-I-A-K-Y-V-V-E-G-D-L-R-R-E-V-T-L-N-I-K-R-L-I-D-L-G-T-Y-R-G-L-R-H-R-R-N-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-K-K-L-I-N-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-F-S-L-N-T-I-A-P-A-L-G-A-K-R-V-G-K-R-V-A-R-G-I-G-S-G-F-G-K-T-A-G-R-G-H-K-G-Q-K-S-R-S-G-C-K-I-K-V-S-F-E-G-G-Q-T-P-L-H-R-R-L-P-K-F-G-F-K-S-R-K-S-I-V-T-Q-E-I-T-L-F-D-L-S-R-I-P-E-N-V-I-D-L-N-V-L-K-K-Y-D-I-V-S-R-K-I-R-F-V-K-I-I-M-S-G-T-F-D-K-P-V-I-I-R-N-L-R-I-S-K-G-A-R-D-L-I-K-S-V-G-G-R-I-E-E-G-E"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-R-Y-S-N-K-Q-T-S-N-I-H-E-L-Q-E-K-L-I-T-V-N-R-V-S-K-T-V-K-G-G-R-V-F-S-F-A-A-L-T-V-V-G-N-V-N-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-S-A-I-Q-K-A-M-E-K-A-R-H-N-M-I-D-I-P-L-N-P-G-R-T-L-Q-H-S-I-I-G-I-Y-T-G-A-R-I-Y-M-K-P-A-S-E-G-T-G-I-I-A-G-G-A-M-R-A-I-L-E-V-V-G-I-H-N-V-L-A-K-A-Y-G-S-T-N-P-I-N-I-V-R-A-T-V-N-A-L-K-N-M-K-S-P-E-M-V-A-E-K-R-G-K-S-L-E-Y-I-L-N-N-Y-T-Y-N-G-R"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-N-K-K-L-L-R-A-R-R-A-L-K-L-R-K-K-L-Y-L-L-G-S-V-R-L-V-V-Y-R-S-L-R-H-M-Y-A-Q-I-V-S-E-D-N-C-N-V-L-V-A-A-S-T-T-E-K-L-I-A-S-K-L-R-V-T-G-N-K-E-A-A-A-V-V-G-Q-V-I-A-E-R-A-F-K-K-G-I-V-H-V-S-F-D-R-S-G-F-K-Y-H-G-R-V-Q-I-L-A-E-Y-A-R-Q-F-G-L-K-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-A-D-M-L-T-V-I-R-N-G-Q-V-A-K-K-D-K-V-Y-V-P-S-S-T-I-K-I-A-I-T-K-V-L-V-E-E-G-F-L-K-D-Y-S-V-L-G-N-I-K-F-I-L-E-I-S-L-K-Y-Y-Q-C-N-K-P-V-I-D-H-I-Q-R-I-S-R-P-S-L-R-V-Y-K-N-K-D-M-L-P-K-V-L-S-G-M-G-V-V-V-V-S-T-S-K-G-V-M-T-D-K-K-A-R-K-L-N-V-G-G-E-I-I-C-Y-V-S"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-P-R-K-S-V-Q-E-R-E-K-K-R-L-R-L-I-N-K-Y-F-L-R-R-S-L-L-R-K-C-V-V-D-L-K-V-S-S-E-E-R-W-N-A-V-L-K-L-Q-T-L-P-R-D-S-S-P-S-R-L-R-N-R-C-G-R-T-G-R-P-H-A-F-L-R-K-F-G-L-S-R-M-K-V-R-E-A-A-M-K-G-E-I-P-G-L-R-K-S-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-R-D-Y-Y-K-S-H-V-V-Y-D-L-M-R-E-F-K-Y-K-S-V-M-Q-V-P-K-I-N-K-I-T-I-S-M-G-V-G-K-S-I-I-N-K-K-F-L-E-R-A-I-E-D-L-E-M-I-S-G-Q-K-P-V-I-T-K-A-R-K-S-I-A-S-F-K-I-R-Q-G-Q-E-I-G-C-K-V-T-L-R-R-K-R-M-W-E-F-F-E-R-L-I-S-I-A-I-P-R-I-R-D-F-R-G-L-S-I-K-S-F-D-G-Y-G-N-Y-T-M-G-I-R-E-Q-I-I-F-P-E-I-N-Y-D-T-I-D-G-I-R-G-M-N-I-T-I-T-T-N-A-V-S-D-K-E-A-Y-V-L-L-R-A-F-R-F-P-L-K-N-N-D-S-I-Y-T-S-T-E-E-H"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-A-N-K-I-R-C-H-D-E-V-V-V-L-T-G-K-D-K-G-K-I-G-R-V-K-F-L-C-L-S-K-K-T-V-I-V-S-G-I-N-V-V-K-K-H-Q-K-P-V-P-N-K-N-Q-P-G-G-I-I-E-K-E-A-F-I-H-L-S-N-V-A-I-F-N-A-A-L-N-K-A-D-R-V-G-F-K-I-K-N-G-K-K-I-R-I-F-K-S-N-G-N-L-I-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-E-R-T-I-L-N-V-A-D-N-S-G-A-R-F-A-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-N-I-G-D-V-I-K-V-T-V-K-E-A-I-P-K-A-K-V-K-K-G-D-V-L-Q-A-V-I-V-R-T-K-K-G-I-R-R-I-D-G-S-I-I-R-F-D-N-N-A-C-V-L-L-N-D-T-N-M-Q-P-L-G-T-R-I-F-G-P-V-T-R-E-L-R-Y-A-N-F-V-R-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-N-N-K-V-H-V-L-Q-G-I-V-I-R-S-K-M-Q-K-S-I-V-V-S-I-N-R-I-V-K-H-S-M-Y-K-K-F-I-N-R-T-T-K-I-Y-V-H-D-T-N-N-I-S-N-V-G-D-I-V-E-I-T-E-C-R-P-I-S-K-T-K-C-W-K-L-T-S-I-I-K-K-Y-N-S-S"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-M-H-K-G-R-N-R-G-I-V-V-N-D-K-I-N-F-G-T-F-A-L-K-S-V-D-R-G-R-L-K-S-C-Q-I-E-S-A-R-R-A-I-T-R-A-I-K-R-Q-G-K-V-W-I-R-I-F-P-D-K-P-I-T-Q-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-V-Q-P-G-K-I-L-Y-E-M-S-G-V-S-K-E-L-A-D-H-A-F-K-L-G-S-S-K-L-P-V-R-T-V-V-T-G-I"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-I-A-R-Y-R-Y-I-R-S-S-A-Q-K-I-R-L-V-A-N-M-I-R-K-K-E-V-V-K-A-I-N-I-L-N-Y-V-N-K-K-A-A-L-L-V-K-K-T-L-E-S-A-I-A-N-A-E-H-N-F-G-L-N-I-D-K-L-R-V-V-K-I-F-V-D-C-G-P-S-I-K-R-V-M-P-R-A-K-G-R-S-D-R-I-V-K-R-T-S-H-L-T-I-V-V-S-D"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-L-R-K-G-P-F-I-D-L-H-L-L-R-K-V-E-K-V-I-K-T-G-D-K-K-P-I-R-T-W-S-R-R-S-T-I-F-P-K-M-I-G-L-T-I-S-V-H-N-G-K-Q-H-I-P-V-F-I-S-D-E-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-S-V-D-K-K-I-K-K-R-Y"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-Y-I-E-R-L-L-K-V-I-K-A-P-H-V-S-E-K-S-S-I-A-L-D-K-N-N-V-I-V-L-K-V-V-N-Y-V-T-K-Q-D-I-R-H-A-V-C-M-L-F-S-V-K-I-K-K-I-N-V-L-M-V-S-G-K-S-K-G-Q-R-Y-N-L-G-Y-R-C-N-W-K-K-A-Y-V-I-L-K-R-G-Y-T-V-D-L-M-N-M-E-Q"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-R-I-R-I-R-L-K-A-F-D-H-R-L-I-D-R-S-T-L-D-I-V-E-T-A-K-R-T-G-A-Q-V-H-G-P-I-P-L-P-T-K-K-E-R-F-T-I-L-V-S-P-H-V-N-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-L-I-D-I-V-D-P-T-D-K-T-V-D-A-L-M-K-L-D-L-A-A-G-V-D-V-Q-I-S-L-G"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-E-K-I-R-N-F-E-S-N-Q-M-K-K-D-I-P-P-L-H-P-G-D-V-V-E-I-S-L-W-I-I-E-G-N-K-K-R-F-Q-I-F-E-G-M-I-I-A-I-K-N-R-G-L-N-S-A-F-T-V-R-K-I-S-S-G-E-G-V-E-R-V-F-Q-I-H-S-P-V-I-K-E-I-N-I-K-K-I-G-V-V-R-R-A-K-L-Y-Y-L-R-N-L-K-G-K-S-A-R-I-K-T-R-L-H-V-N"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-V-I-V-I-N-S-T-P-I-N-P-I-V-I-G-R-I-K-G-A-Y-G-I-L-G-W-V-K-I-L-S-F-T-E-K-I-E-D-I-F-V-Y-N-P-W-F-I-F-F-R-S-K-W-K-V-I-K-L-E-Y-W-R-L-M-N-N-K-N-Y-I-V-K-F-F-N-V-S-D-R-N-H-A-M-A-L-S-Q-H-N-L-V-V-E-S-I-Q-F-P-K-L-Y-N-K-D-E-Y-Y-W-K-D-I-I-G-C-K-I-M-T-I-N-G-K-C-L-G-R-V-I-S-I-I-D-T-K-A-H-D-I-L-V-V-R-S-E-E-Y-G-F-T-K-Y-V-D-C-L-I-P-F-I-L-K-K-I-I-K-D-V-D-L-I-K-N-I-V-V-V-D-W-E-I-Y-K-F"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-I-I-G-D-D-I-T-V-T-V-L-G-V-K-G-N-Q-I-R-I-G-I-N-A-P-K-K-V-S-I-H-R-E-E-I-Y-Q-R-I-Q-D-E-K-T-K-Q-D-H-I-L-D-E-V"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-N-D-K-K-N-A-F-P-I-K-L-T-H-S-A-A-D-Q-V-K-K-L-I-S-S-Q-D-Y-A-E-K-L-D-L-K-L-R-V-Y-I-L-G-G-G-C-G-G-F-Q-Y-K-F-I-L-D-D-Q-V-S-N-D-D-C-V-I-E-S-N-G-A-I-V-V-V-D-P-M-S-L-Q-Y-L-F-G-G-I-I-D-Y-Y-E-G-L-E-G-S-K-F-L-V-V-N-P-N-A-K-G-V-C-S-C-G-S-S-F-N-I"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-K-S-A-K-K-F-I-I-K-S-K-K-N-R-N-R-N-L-S-N-R-S-M-L-K-T-F-I-K-K-V-N-I-A-I-N-K-R-N-I-S-E-A-L-F-A-F-K-N-M-Q-K-C-I-D-R-Q-S-I-K-G-L-I-H-K-N-K-A-A-R-C-K-S-K-I-F-R-R-I-S-L-L-I-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-H-Y-N-A-E-Q-K-S-K-I-I-L-K-F-G-F-N-N-I-K-N-T-G-I-T-E-V-Q-V-A-L-L-T-Q-R-I-N-A-L-K-S-H-F-N-K-H-K-Q-D-H-H-S-R-R-G-L-L-H-I-V-T-R-R-R-K-L-L-K-Y-L-K-K-S-S-V-L-R-Y-N-N-L-I-E-S-L-A-L-R-H"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-Y-T-K-R-I-N-R-L-Q-R-I-S-Q-E-I-Q-R-K-V-A-I-I-I-H-H-K-V-H-D-P-R-V-G-L-P-T-I-S-G-V-Q-V-S-R-D-L-K-N-A-K-I-F-I-T-F-L-D-K-N-N-I-E-E-I-N-F-S-I-L-I-L-Q-K-A-S-G-F-I-R-F-L-L-A-N-S-M-N-L-R-T-V-P-V-L-L-F-K-Y-D-Y-S-L-K-E-G-I-K-I-C-K-L-I-S-Q-L-K"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-I-G-S-K-Q-Y-Y-V-R-T-G-Q-V-I-F-I-D-R-V-K-L-D-I-G-N-Q-I-E-F-N-Q-V-L-L-I-R-D-M-K-N-I-Y-I-G-N-P-F-I-Q-N-G-K-I-I-A-D-I-L-D-H-S-L-G-K-K-I-R-I-V-K-F-R-R-R-K-H-F-R-K-F-Q-G-H-R-Q-C-M-T-K-I-K-V-V-K-I-N-S-N-N-S-D-I-E-C-Y-K-S-V-D-I-E-T-K-I-G-E-E-V-H-G-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-L-D-S-I-D-K-V-G-K-I-G-S-E-I-I-V-K-S-G-Y-A-R-N-F-L-F-P-K-S-K-A-V-L-S-T-K-K-N-L-A-I-F-K-K-Q-Q-H-I-L-K-S-N-L-D-S-K-R-L-K-A-E-F-R-A-K-A-I-N-D-L-G-S-I-T-I-T-V-K-S-S-I-H-G-K-L-F-G-S-I-G-S-R-D-I-A-K-L-I-T-E-S-V-G-F-E-V-H-K-S-Q-I-R-L-P-N-R-D-A-L-K-S-I-G-E-H-N-V-C-I-H-V-Y-N-E-I-Y-A-N-L-T-V-H-I-L-N-S-V-L-F-Q-D-K-S-K-K-S"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-I-L-P-R-Y-I-R-H-R-K-F-C-R-F-T-A-D-K-C-I-Y-V-D-Y-K-D-L-S-K-I-Q-H-S-I-I-E-N-A-K-I-I-P-S-R-I-T-G-T-R-S-K-Y-Q-R-Q-L-A-R-A-I-K-I-A-R-F-L-S-L-L-P-Y-I-D-Q-N-R"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-Y-Y-E-I-V-L-I-I-H-P-D-S-D-N-Q-I-D-N-L-V-N-Y-Y-S-E-I-I-I-N-S-T-G-K-I-H-R-L-E-N-W-G-R-R-Q-L-A-Y-A-I-K-N-L-N-K-A-Y-Y-L-L-L-N-I-E-I-S-K-N-I-L-D-I-L-D-N-D-F-R-F-N-E-I-I-L-R-Y-L-I-M-R-T-K-N-I-I-V-D-P-S-A-M-V-K-K-K-D-D-N-N-Q-E-G-N-N-S-T-V-C-I"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-N-E-D-N-L-I-W-I-D-L-E-M-T-G-L-N-P-E-R-D-R-I-L-E-I-A-T-L-I-T-D-N-E-L-S-I-L-S-E-G-P-V-L-T-I-Y-Q-P-E-S-Q-L-L-L-M-D-E-W-N-T-Y-T-H-S-S-N-G-L-L-K-E-V-R-S-S-K-L-N-E-C-D-A-S-I-L-V-L-K-F-L-K-N-W-V-P-C-K-S-S-P-M-C-G-S-S-V-A-Q-D-R-R-F-L-L-K-Y-M-S-E-L-E-S-Y-F-S-Y-R-Y-L-D-V-S-T-I-K-E-L-M-F-R-W-R-P-D-L-K-T-G-L-Q-L-H-K-S-H-R-A-L-A-D-I-Q-E-S-V-L-E-L-K-Y-Y-R-K-Y-F-I-N-C-N"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-33 is required for alleviation ### SEQUENCE -M-L-Y-N-I-N-E-L-K-V-G-L-K-V-I-Q-N-K-E-P-Y-V-I-I-K-N-E-C-I-K-P-G-K-G-Q-S-F-N-R-V-R-F-K-Q-I-K-S-G-K-I-L-E-K-T-L-K-P-G-D-L-V-E-S-A-N-I-V-E-T-E-L-I-Y-V-Y-R-D-R-D-L-W-F-F-M-N-R-D-S-F-D-Q-I-S-V-H-F-D-I-L-G-K-S-V-K-W-M-V-E-Q-L-V-Y-V-V-V-F-W-D-N-N-P-I-L-V-I-P-P-E-F-I-K-L-K-I-I-K-T-N-L-I-T-K-N-I-S-T-A-S-G-N-K-L-A-V-V-S-T-G-A-V-V-K-V-P-F-F-I-Q-S-G-E-L-I-K-V-N-T-H-S-G-S-Y-I-S-R-I-K"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-K-N-H-L-S-K-R-V-R-L-L-K-I-N-E-F-F-F-V-F-Q-K-P-Q-R-I-K-V-H-S-M-T-L-F-S-R-S-N-K-L-N-F-P-R-I-G-L-A-I-S-K-K-Y-I-K-H-S-H-E-R-N-R-I-K-R-H-V-R-E-T-F-R-T-H-K-H-N-L-L-S-L-D-F-I-L-T-V-H-S-K-Q-I-L-S-L-T-N-N-N-L-I-E-E-L-K-K-L-W-Y-H-Y-Q-N-Y-Q-Q-K-S"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-I-V-N-S-C-Q-L-N-V-V-S-V-E-K-S-I-F-S-G-V-I-K-K-I-Y-V-M-G-V-E-G-E-L-G-I-F-P-G-H-S-P-L-L-T-L-I-K-P-G-L-L-K-I-F-Q-V-Y-N-N-E-Y-L-Y-L-S-G-G-I-L-E-V-Q-P-T-V-I-T-I-L-A-D-V-A-I-R-A-K-D-L-D-E-K-K-V-R-D-S-K-R-L-S-E-E-K-I-K-K-M-R-H-G-D-V-D-Y-I-K-I-S-M-E-I-S-K-A-I-A-Q-L-R-L-I-E-L-T-K-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-Y-L-N-A-T-I-L-G-Q-V-I-A-F-I-L-F-V-W-F-C-M-K-Y-V-W-N-P-L-M-S-V-I-E-E-R-Q-K-K-I-I-D-S-L-E-S-I-K-T-S-K-M-E-S-E-R-I-R-N-E-A-L-A-C-L-K-Q-A-H-I-K-S-E-E-I-I-K-Y-A-Y-E-C-K-M-Q-I-L-H-T-A-Q-N-E-A-Y-Q-E-R-D-K-I-L-S-Q-T-Q-I-Q-I-D-Q-E-R-E-R-I-I-S-E-L-R-N-H-V-S-K-L-V-I-E-S-T-E-K-V-I-D-T-S-I-N-K-I-I-D-Y-D-F-V-D-K-I-I-K-Q-L-S-N-Y-E-D"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-V-L-T-N-F-F-L-R-K-K-T-S-T-T-A-S-I-A-K-K-R-L-H-I-I-V-T-E-R-K-I-D-N-T-P-E-L-N-Y-L-P-K-F-K-K-D-L-L-R-I-I-H-Q-Y-I-H-E-P-K-K-I-S-I-Q-L-Q-E-Q-D-N-N-A-Y-M-L-Q-L-T-I-S-F-L-T-K-N-Q-D-L-I-N-S-K-K-Q-D-N-T-T-V"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-L-H-I-F-Y-I-Y-S-K-S-R-K-F-W-A-I-L-I-C-S-S-I-S-L-I-S-I-A-L-L-N-Q-F-F-F-L-L-K-P-C-I-L-C-I-Y-Q-R-C-S-L-F-G-I-T-I-A-G-L-I-A-L-I-S-P-K-T-T-L-L-R-L-F-S-I-F-I-W-L-Y-S-A-I-K-G-L-Y-F-S-N-I-H-M-Q-T-T-L-H-P-S-S-S-L-T-C-D-L-F-V-S-F-P-N-W-L-P-L-N-K-W-Y-P-I-I-F-D-S-K-I-S-N-C-Y-S-Y-P-Q-Y-L-L-Y-L-E-I-S-Q-W-M-L-L-F-F-L-I-Y-L-I-I-A-I-F-T-I-I-S-Q-C-H-N-L-F-Q-K-K"} +{"text": "### FUNCTION Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress ### SEQUENCE -M-I-A-S-K-F-K-I-G-Q-Q-V-R-H-K-L-L-G-Y-L-G-V-V-I-D-I-D-P-E-Y-S-L-E-K-P-T-L-D-E-V-T-K-N-D-S-L-R-K-F-P-W-Y-H-V-V-M-E-D-D-E-G-K-P-I-H-T-Y-L-A-E-I-Q-L-G-Y-E-D-T-V-I-H-P-E-Q-S-T-L-D-D-L-A-E-S-I-R-L-Q-L-Q-T-P-R-L-R-N"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-I-V-E-E-K-V-K-T-I-I-A-E-Q-L-G-V-K-Q-E-E-V-V-N-H-A-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-I-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-A-A-I-D-F-I-H-T-N-Q-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-I-K-E-D-N-I-E-M-H-G-I-V-L-D-T-L-P-N-T-M-F-R-V-Q-L-E-N-G-H-K-I-T-A-H-I-S-G-K-I-R-K-N-Y-I-R-I-L-T-G-D-K-V-T-V-E-L-T-P-Y-D-L-S-K-G-R-I-I-F-R-S-R"} +{"text": "### FUNCTION Transcription regulator that can specifically activate or repress expression of target genes ### SEQUENCE -M-E-S-S-L-G-S-D-L-A-R-L-V-R-I-W-R-A-L-I-D-Y-R-L-K-P-L-K-L-T-Q-T-H-W-I-T-L-H-N-I-Y-Q-L-P-P-D-Q-S-Q-I-Q-L-A-K-A-I-G-I-E-Q-P-S-L-V-R-T-L-D-Q-L-E-S-K-G-L-I-V-R-N-I-C-S-N-D-R-R-A-K-R-I-T-L-T-E-L-A-K-P-V-I-N-Q-V-N-Q-V-I-N-V-T-R-N-E-V-F-Y-G-L-R-V-E-E-I-Q-Q-L-N-N-I-I-A-K-L-E-R-N-I-I-N-L-Y-N-K-T"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-V-K-N-S-V-T-A-H-S-R-H-K-K-I-L-K-R-A-T-G-Y-Y-G-A-R-S-R-T-Y-R-V-A-Y-Q-A-I-I-K-A-G-Q-Y-A-Y-R-D-R-K-Q-K-K-R-I-F-R-Q-L-W-I-S-H-I-N-A-V-A-R-Q-Y-G-L-S-Y-N-N-L-I-N-N-L-Y-K-S-S-I-Y-I-N-R-K-M-L-A-E-L-A-T-S-D-Q-V-A-F-L-N-L-V-N-N-I-K-I-H-S-K"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-Q-S-F-R-L-H-R-I-N-R-E-I-T-I-K-K-I-R-L-T-G-A-D-G-K-Q-I-G-V-V-N-F-N-E-A-I-K-Q-A-E-D-L-E-L-D-L-V-E-I-S-P-N-S-D-P-P-V-C-K-I-M-N-Y-G-K-F-L-Y-E-K-N-K-S-T-K-E-Q-K-K-K-Q-K-I-I-H-I-K-E-I-K-F-R-P-G-T-D-E-G-D-Y-Q-V-K-L-R-N-I-I-K-F-L-N-D-G-Y-K-I-K-I-T-L-R-F-R-G-G-E-L-I-H-Q-Q-I-G-V-R-V-L-H-R-I-S-Q-D-L-H-D-L-M-T-V-E-I-F-P-N-K-V-E-G-R-Q-M-T-M-I-L-A-P-K-K-K-P-V"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-V-S-R-V-I-L-N-L-Q-L-V-C-A-N-T-Q-G-I-P-A-N-N-K-I-K-L-W-I-K-K-I-F-F-S-S-K-K-K-I-E-L-T-I-R-I-V-D-I-Q-E-M-L-Y-L-N-W-Y-Y-L-G-K-K-Y-P-T-N-V-L-S-F-P-F-E-P-P-S-E-I-Q-T-S-L-L-G-D-I-V-I-C-K-Q-I-I-E-Y-E-N-R-K-N-N-I-F-S-D-V-H-W-A-H-M-I-I-H-G-S-L-H-L-L-G-Y-D-H-I-C-D-E-D-A-E-L-M-N-A-M-E-L-N-I-I-R-T-L-G-Y-K-T-C-C-F-L"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-I-S-H-T-D-H-Q-L-T-L-I-K-E-N-I-K-F-I-P-N-Y-P-K-Q-G-I-L-F-R-D-I-T-A-L-L-E-N-P-H-A-Y-S-A-C-I-K-L-L-A-D-H-Y-K-N-H-Q-L-T-K-I-V-G-V-E-A-R-G-F-L-F-G-S-P-L-A-L-I-L-K-L-G-F-I-P-A-R-K-A-G-R-L-P-R-N-T-I-S-E-S-Y-V-L-E-Y-G-T-G-C-L-E-M-H-N-D-S-I-I-P-G-D-R-V-L-I-V-D-D-L-L-A-T-G-G-T-I-K-A-V-V-K-L-I-R-R-L-G-G-E-V-Y-H-A-A-F-V-I-D-L-E-K-L-G-G-K-L-L-L-E-K-I-G-V-H-P-Y-S-L-V-I-F-S-D"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-I-T-D-T-C-I-L-H-I-E-E-V-L-E-L-L-P-H-R-F-P-F-L-L-V-D-R-V-L-N-F-E-K-G-K-F-L-R-A-V-K-N-V-S-F-N-E-P-F-F-Q-G-H-F-P-G-K-P-I-F-P-G-V-L-I-L-E-A-M-A-Q-A-T-G-I-L-A-F-K-S-M-G-K-L-A-P-G-E-F-Y-Y-F-A-A-I-D-E-A-R-F-K-R-P-V-Q-P-G-D-Q-M-I-L-N-V-E-F-I-K-E-R-C-G-V-A-R-F-K-G-I-A-T-V-N-E-E-M-A-C-E-A-S-M-M-C-A-R-R-K-E-I"} +{"text": "### FUNCTION Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm ### SEQUENCE -M-K-N-R-V-Y-M-L-G-I-I-I-W-L-A-Q-I-N-Y-V-N-A-A-N-K-I-V-V-M-N-V-A-N-I-F-Q-Q-S-A-Q-R-T-E-I-I-K-Q-L-E-Y-E-F-K-D-R-A-A-E-L-E-M-M-E-H-D-L-Q-T-K-M-Q-T-L-Q-R-D-G-A-T-M-T-A-S-D-R-N-T-L-E-K-S-L-I-A-Q-R-E-L-F-S-N-K-A-K-L-F-Q-Q-E-N-H-A-R-Q-T-E-E-R-D-K-I-L-D-M-I-Y-K-I-V-K-N-I-A-K-K-E-N-Y-D-I-V-I-D-T-N-A-V-V-Y-F-S-S-H-I-K-D-I-T-D-S-V-S-N-Q-M-R-V-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-D-I-I-D-D-F-Q-K-D-V-T-I-N-M-Q-K-C-I-D-N-F-K-I-N-I-N-K-I-H-V-G-R-I-S-P-D-I-L-S-F-I-K-I-E-Y-Y-G-V-I-T-P-L-C-Q-L-T-N-T-V-V-E-Q-P-R-T-L-I-I-T-V-F-D-S-S-M-I-K-F-I-E-K-A-I-L-E-S-N-L-G-C-T-P-V-S-T-G-N-T-I-R-V-T-F-P-T-L-T-E-S-R-R-Y-S-L-I-K-M-V-R-S-E-S-E-K-S-K-V-L-I-R-N-I-R-R-V-S-N-D-K-L-K-T-F-L-R-N-K-E-I-N-K-D-N-E-H-Y-F-Q-N-E-I-Q-N-L-T-D-I-W-I-K-K-I-I-L-I-T-K-E-K-E-L-E-L-M-K-F"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-D-N-G-Y-R-L-N-V-G-I-V-L-C-N-T-Y-G-Q-V-L-W-A-K-R-Y-K-Q-C-S-W-Q-F-P-Q-G-G-I-N-I-G-E-T-P-E-Q-A-M-Y-R-E-L-F-E-E-I-G-L-N-Y-C-D-V-R-I-L-S-I-T-R-C-W-F-C-Y-K-L-P-T-Q-L-V-R-W-R-I-K-P-L-C-L-G-Q-K-Q-K-W-F-L-L-K-L-L-S-K-D-T-K-I-N-M-K-T-S-K-V-C-T-F-D-T-W-Q-W-V-S-L-W-Y-P-I-R-Q-V-V-F-F-K-R-H-V-Y-R-K-V-M-K-E-F-V-K-L-I-I-S-R"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-I-K-K-I-A-I-I-M-A-F-D-F-G-T-K-K-I-G-I-A-I-G-Q-K-I-T-G-T-T-Q-S-L-E-I-L-P-S-K-F-G-I-P-N-W-K-K-I-E-H-I-F-N-V-W-K-P-N-K-L-I-V-G-L-P-L-K-M-N-G-N-T-Q-H-I-T-L-L-S-K-R-F-A-V-Q-L-T-H-R-F-K-I-T-V-E-M-H-D-E-R-F-T-T-I-E-A-R-S-I-Y-F-Q-H-F-R-Y-Y-Y-R-K-K-T-T-P-I-D-S-I-A-A-E-I-I-L-K-S-W-L-N-Q-N-D"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-S-I-T-R-R-F-A-R-L-C-A-L-Q-A-L-Y-A-W-Q-L-S-K-N-D-Y-T-M-I-S-N-Y-V-I-K-I-Q-N-I-Q-N-F-N-I-S-Y-F-L-T-L-Y-I-G-V-I-H-T-I-K-E-L-N-T-L-M-I-P-Y-L-S-R-G-L-K-A-I-D-Y-I-E-Y-S-V-L-L-I-A-L-F-E-L-T-Q-C-C-D-V-P-Y-K-V-V-I-N-E-A-I-E-L-A-K-I-F-G-S-E-K-S-H-K-F-I-N-G-V-L-D-K-I-I-T-E-K-L-Y-K-G"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-I-I-N-I-K-I-I-R-N-N-I-N-N-F-S-L-P-Q-H-I-T-P-G-S-A-G-L-D-L-L-A-C-I-E-K-P-V-S-I-L-P-K-E-T-R-L-I-P-T-G-I-A-I-Y-I-E-D-I-E-V-A-G-I-I-L-P-R-S-G-L-G-H-Y-Y-G-I-V-L-G-N-T-I-G-L-I-D-S-D-Y-Q-G-E-I-M-I-S-L-W-N-R-G-S-N-K-F-I-L-Y-P-G-K-R-I-A-Q-L-L-F-I-S-I-L-R-V-K-L-S-L-V-K-S-F-D-P-F-M-K-T-I-R-G-V-K-G-F-G-H-S-M"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-N-I-H-P-Q-Y-N-V-I-S-A-S-C-S-C-G-N-V-I-H-V-R-S-T-L-K-H-N-I-N-L-D-V-C-D-A-C-H-P-F-Y-T-G-T-Q-R-I-I-D-T-R-G-R-V-N-L-F-N-K-R-F-N-K-N-N-K-N-P-F-I"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-V-T-I-N-Q-L-V-G-N-A-R-S-I-R-V-V-K-S-S-V-P-A-L-E-S-C-P-Q-K-R-G-V-C-I-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-L-E-V-T-C-Y-I-G-G-E-G-H-N-L-Q-E-H-A-S-I-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-V-V-R-G-A-L-D-C-S-G-V-K-D-R-K-N-G-R-S-K-Y-G-T-K-K-L-K-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-R-V-T-V-K-R-V-I-L-A-D-P-R-F-K-S-D-L-L-S-K-F-I-N-I-L-M-F-N-G-K-K-S-V-A-E-S-I-I-Y-S-A-L-D-M-V-L-D-R-S-S-K-D-S-C-M-E-L-F-E-E-A-L-D-N-V-R-P-V-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-L-V-R-R-N-T-L-A-M-R-W-I-I-E-S-A-R-K-R-N-D-K-S-M-E-M-R-L-A-N-E-L-F-D-A-S-E-G-K-G-N-A-V-K-K-R-E-E-V-H-R-L-A-E-S-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-I-V-K-K-K-V-Q-S-C-I-K-L-Q-I-E-A-R-S-A-T-P-S-P-P-I-G-P-A-L-G-Q-Q-G-I-N-I-M-K-F-C-K-D-F-N-T-R-T-A-D-F-E-M-G-L-I-L-P-V-V-I-T-V-Y-V-D-R-S-F-S-F-V-I-K-T-P-T-A-V-F-L-L-K-K-A-A-G-I-K-S-G-S-E-K-P-K-C-V-S-V-G-K-V-L-I-S-Q-I-Y-E-I-A-K-I-K-L-I-D-M-T-S-L-N-L-E-S-A-S-K-S-I-M-G-T-A-R-S-I-G-L-E-V-E-D-N-L"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-V-L-S-I-K-K-K-E-Q-I-V-C-K-I-Q-E-V-F-K-I-S-S-S-A-V-I-A-S-L-S-N-I-T-S-N-S-M-N-Q-L-R-K-E-S-R-D-C-G-V-Y-I-K-V-I-P-N-T-L-L-R-R-A-L-K-N-S-L-Y-E-C-L-S-N-F-C-I-G-Q-N-I-I-A-F-S-I-N-N-P-S-D-A-A-R-V-L-V-N-F-S-K-N-N-E-Y-F-K-I-A-G-A-V-C-E-G-N-F-I-D-K-D-Q-I-D-M-L-S-R-L-P-N-Y-N-E-S-L-L-Q-L-I-L-I-L-K-V-M-S-V-G-K-L-I-N-V-L-K-I-L-S-N-Q-I-I-E-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-L-K-K-E-E-V-L-D-A-I-S-E-M-S-V-M-D-I-M-Q-L-I-S-M-I-E-K-K-F-G-V-S-A-A-S-S-H-I-S-S-V-E-N-V-V-T-E-S-E-S-T-Q-V-E-Q-T-E-F-T-V-I-L-S-S-I-G-G-N-K-I-P-V-I-K-A-V-R-S-I-T-G-L-G-L-K-E-A-K-D-L-V-E-S-A-P-V-T-L-K-E-S-V-S-K-D-D-A-D-N-L-K-K-T-L-E-S-V-G-A-S-V-E-I-K"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-I-D-N-N-K-H-N-Q-D-I-N-A-S-S-A-N-T-I-K-K-D-E-L-S-E-S-A-C-K-I-D-S-I-I-D-P-K-D-D-Q-I-I-Q-L-Q-I-Q-L-A-Q-I-K-E-H-E-R-N-T-I-L-R-L-K-A-E-I-E-N-I-Q-R-R-N-I-Q-E-I-E-K-A-H-K-F-A-L-D-R-F-V-S-E-L-L-P-V-I-D-N-L-E-R-T-L-G-I-I-D-R-S-N-T-T-L-S-A-I-I-E-G-I-D-L-T-L-K-S-F-L-D-T-V-Y-K-F-G-V-K-S-I-H-E-I-H-I-P-F-N-P-E-I-H-Q-A-I-S-T-M-E-S-E-K-Y-E-S-N-Q-V-L-T-I-V-Q-K-G-Y-S-L-N-G-R-L-V-R-P-A-M-V-I-V-A-K-S-K-S"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-Y-G-I-G-I-D-I-V-E-I-N-R-I-K-K-I-V-I-R-S-G-D-K-L-A-K-R-I-L-R-K-S-E-L-K-L-Y-Y-S-K-E-Y-P-V-R-F-L-S-K-R-F-A-A-K-E-A-V-L-K-A-F-G-T-G-M-S-Q-G-I-T-F-S-Q-F-E-I-F-N-D-D-L-G-R-P-M-L-R-F-F-S-Q-A-A-V-L-A-K-K-L-D-L-V-R-T-H-V-S-V-S-D-T-G-L-Y-A-C-S-I-V-I-F-E-C"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-L-I-I-K-A-I-L-R-T-E-I-K-K-S-I-T-R-K-I-R-K-N-G-G-C-P-A-V-I-Y-N-K-N-K-S-P-N-I-N-V-Q-L-S-N-K-D-L-S-H-P-E-N-V-H-Y-F-L-K-N-N-K-V-Q-I-L-I-N-N-E-F-T-I-T-A-K-I-Q-D-V-Q-Y-H-P-Y-K-S-N-I-I-H-I-D-F-I-H-I-T-T-Q-S-R-S"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-A-D-Q-D-Q-T-N-Q-Q-A-G-S-D-A-P-S-F-N-L-Q-R-V-Y-L-K-D-L-S-L-E-M-P-N-A-P-H-V-F-L-E-Q-E-A-P-Q-V-E-V-S-I-N-V-G-G-Q-R-L-A-E-T-V-F-E-S-T-V-T-V-T-V-T-T-R-V-N-D-K-V-L-Y-L-V-E-G-T-Q-A-G-I-F-E-L-A-N-I-P-A-E-Q-M-D-P-L-L-G-I-V-C-P-T-M-L-Y-P-Y-L-R-A-N-V-A-D-A-I-T-R-T-S-L-P-A-L-H-L-A-E-V-N-F-Q-A-L-Y-E-Q-R-L-A-E-M-A-Q-Q-Q-P-D-A-A-N-G-N-D-S-G-I-I-L-P-P-G-A-T-R-Q"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-L-L-S-I-L-R-Y-P-D-P-R-L-H-K-T-A-K-P-V-A-V-V-D-D-R-I-R-Q-L-V-R-D-M-A-D-T-M-Y-D-A-P-G-V-G-L-A-A-T-Q-V-D-V-H-E-R-V-V-V-I-D-V-S-E-E-G-N-D-L-R-V-L-I-N-P-E-I-T-W-K-S-D-E-R-Q-T-Y-E-E-G-C-L-S-V-P-G-I-Y-D-E-V-E-R-A-A-R-I-R-C-K-A-L-D-Q-Q-G-Q-P-Y-E-F-E-A-D-G-L-L-A-V-C-V-Q-H-E-I-D-H-L-D-G-K-V-F-V-E-Y-L-S-N-L-K-Q-N-R-I-K-T-K-L-K-K-A-E-R-E-A-E-R-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-P-R-A-T-L-P-A-E-A-R-L-H-R-P-S-E-F-A-A-A-L-K-G-R-R-L-A-R-G-A-F-F-I-V-S-A-S-P-C-A-P-A-D-D-Q-P-A-R-A-R-L-G-L-V-I-A-K-R-F-A-A-R-A-V-T-R-N-T-L-K-R-V-I-R-E-A-F-R-A-R-R-L-A-L-P-A-Q-D-Y-V-V-R-L-H-S-K-L-T-P-A-S-L-T-A-L-K-R-S-A-R-A-E-V-D-A-H-F-T-R-I-A-R"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-A-L-N-E-Q-D-V-A-R-I-A-R-L-A-R-I-E-L-T-P-D-Q-R-G-R-A-Q-A-E-L-N-G-I-L-H-L-I-E-R-L-Q-A-V-D-T-Q-G-V-E-P-L-A-H-P-L-S-A-H-E-D-I-T-L-R-L-R-E-D-A-V-S-E-Q-A-T-E-A-R-R-A-E-L-L-A-N-A-P-E-S-A-D-G-L-F-L-V-P-K-V-I-E"} +{"text": "### FUNCTION Component of the type IV secretion system ptl required for secretion of assembled pertussis toxin through the outer membrane ### SEQUENCE -M-I-H-A-H-S-N-A-R-L-L-R-W-A-I-L-A-I-A-P-V-T-L-G-A-C-A-P-N-G-P-P-G-L-P-Y-P-D-G-K-P-L-I-P-I-N-T-A-A-P-E-Q-G-S-S-C-Q-T-R-A-P"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-V-S-F-T-E-L-M-V-I-G-V-I-A-L-V-V-I-G-P-E-R-L-P-K-V-A-R-T-I-G-H-L-L-G-R-A-Q-R-Y-V-N-D-V-K-S-D-I-R-R-E-I-E-L-D-E-L-R-K-F-K-N-E-M-D-E-T-A-R-S-M-Q-T-S-L-R-E-T-E-D-T-L-R-D-S-T-Q-A-L-R-A-E-L-D-D-T-A-R-D-A-S-K-A-V-N-G-A-D-A-P-A-E-P-A-P-A-V-A-S-D-T-D-T-R-S-I-A-P-P-A-A-A-T-P-A-D-K-T-P-P-T-G-S-A-T"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-I-W-H-W-L-I-V-L-V-I-I-A-L-V-F-G-T-K-K-L-R-N-V-G-S-D-L-G-S-A-V-K-G-F-K-E-G-M-K-D-A-S-A-D-K-P-A-D-Q-V-T-Q-Q-R-V-S-D-D-T-I-D-V-Q-A-K-E-K-S-N-S"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-T-E-T-E-F-L-A-L-V-D-Q-V-L-D-S-I-E-S-Q-A-D-D-W-A-A-G-L-D-V-D-I-E-A-T-R-S-G-N-V-L-T-L-V-F-E-D-G-T-Q-V-V-V-N-V-Q-A-A-M-Q-E-L-W-V-A-A-R-S-G-G-F-H-Y-R-Y-D-G-Q-H-W-N-D-T-R-G-G-P-R-L-P-D-A-L-S-Q-I-C-S-E-A-A-G-V-P-V-S-V-R-L"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-A-S-T-S-G-A-S-R-V-R-K-K-V-K-K-N-V-S-D-G-I-A-H-V-H-A-S-F-N-N-T-I-I-T-I-T-D-R-Q-G-N-A-L-S-W-A-T-S-G-G-A-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-T-A-G-R-V-A-M-E-Y-G-I-K-T-L-E-V-R-I-K-G-P-G-P-G-R-E-S-S-V-R-A-L-N-A-L-G-I-K-I-S-S-I-A-D-I-T-P-V-P-H-N-G-C-R-P-P-K-R-R-R-I"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-P-Q-Q-H-A-E-I-G-L-T-A-I-F-G-I-G-R-T-R-A-R-K-I-C-E-A-A-G-V-P-V-T-K-K-V-K-D-L-T-D-A-E-L-E-R-I-R-E-H-I-G-V-F-A-V-E-G-D-L-R-R-E-V-Q-L-S-I-K-R-L-I-D-L-G-T-Y-R-G-M-R-H-K-R-G-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-R-A-A-A-S-L-K-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-V-I-Q-M-Q-G-E-V-L-E-N-L-P-N-A-T-F-R-V-K-L-E-N-G-H-V-V-L-G-H-I-S-G-K-M-R-M-H-Y-I-R-I-L-P-G-D-K-V-T-V-E-L-T-P-Y-D-L-T-R-A-R-I-V-F-R-S-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-S-D-I-Q-L-N-T-L-K-P-A-E-G-S-K-H-A-K-R-R-V-G-R-G-I-G-S-G-L-G-K-T-A-G-R-G-H-K-G-Q-K-S-R-S-G-G-F-H-K-V-G-F-E-G-G-Q-M-P-L-Q-R-R-L-P-K-R-G-F-T-P-L-G-Q-H-L-Y-A-E-V-R-L-S-E-L-Q-L-M-E-A-E-E-I-D-V-Q-A-L-K-A-A-G-V-V-G-Q-S-V-R-Y-A-K-V-I-K-S-G-E-L-S-R-K-V-V-L-R-G-I-T-A-T-A-G-A-R-A-A-I-E-A-A-G-G-S-L-A"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-T-K-V-Q-G-K-H-A-A-E-K-E-N-D-D-G-L-R-E-K-M-I-A-V-N-R-V-S-K-V-V-K-G-G-R-T-M-S-F-A-A-L-S-V-V-G-D-G-D-G-R-I-G-M-G-K-G-K-A-R-E-V-P-V-S-V-Q-K-A-M-E-Q-A-R-R-G-M-F-K-V-A-L-K-N-G-T-L-H-H-T-V-V-G-K-H-G-A-S-T-V-L-I-S-P-A-A-E-G-T-G-V-I-A-G-G-P-M-R-A-I-F-E-V-M-G-V-R-N-V-V-A-K-S-L-G-S-S-N-P-Y-N-L-V-R-A-T-L-N-G-L-R-A-S-L-T-P-A-E-V-A-A-K-R-G-K-S-V-E-E-I-L-G"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-V-S-R-L-R-R-A-V-P-T-R-R-K-I-A-Q-L-R-V-H-R-L-S-V-F-R-S-N-L-H-I-Y-A-N-I-I-S-P-E-G-D-R-V-L-V-S-A-S-T-L-E-A-E-V-R-A-Q-L-G-G-A-G-K-G-G-N-A-T-A-A-A-L-V-G-K-R-V-A-E-K-A-K-A-A-G-I-E-L-V-A-F-D-R-S-G-F-R-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-A-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-A-K-Y-P-V-E-L-P-K-G-V-E-A-S-I-Q-P-D-Q-I-T-V-K-G-P-L-G-I-L-V-Q-S-L-T-G-D-V-N-V-A-Q-E-D-G-K-L-T-F-V-V-A-N-D-S-R-H-A-N-A-M-S-G-T-L-R-A-L-V-A-N-M-V-T-G-V-S-K-G-F-E-R-K-L-N-L-V-G-V-G-Y-R-A-Q-I-Q-G-D-A-V-K-L-Q-L-G-F-S-H-D-V-V-H-Q-L-P-A-G-V-K-A-E-C-P-T-Q-T-E-I-V-I-K-G-P-N-K-Q-V-V-G-Q-V-A-A-E-I-R-K-Y-R-E-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-R-V-V-I-K-E-T-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-S-D-P-I-A-D-M-L-T-R-I-R-N-A-Q-Q-V-D-K-T-T-V-T-M-P-A-S-K-L-K-V-A-I-A-T-V-L-K-D-E-G-Y-I-D-G-Y-S-V-K-G-T-Q-A-K-P-E-L-E-I-T-L-K-Y-Y-A-G-R-P-V-I-E-R-I-E-R-V-S-R-P-G-L-R-I-Y-K-G-R-T-S-I-P-Q-V-M-N-G-L-G-V-A-I-V-S-T-S-R-G-V-M-T-D-R-K-A-R-A-N-G-V-G-G-E-V-L-C-Y-V-A"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-L-S-L-I-N-R-D-I-K-R-A-K-L-A-D-K-Y-A-A-K-R-A-E-L-K-A-I-I-D-D-Q-S-K-T-D-E-E-R-Y-Q-A-R-L-K-L-Q-Q-L-P-R-N-A-N-P-T-R-Q-R-N-R-C-V-V-T-G-R-P-R-G-V-F-R-K-F-G-L-T-R-H-K-L-R-E-M-A-M-K-G-E-V-P-G-M-T-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-R-L-Q-E-F-Y-K-S-K-V-V-A-D-L-Q-A-K-F-G-Y-K-C-V-M-E-V-P-R-I-T-K-I-T-L-N-M-G-V-S-E-A-V-A-D-K-K-V-I-E-H-A-V-S-D-L-T-K-I-S-G-Q-K-P-V-V-T-K-T-R-K-A-I-A-G-F-K-I-R-E-N-Y-P-I-G-C-M-V-T-L-R-G-Q-R-M-Y-E-F-L-D-R-L-V-A-V-A-L-P-R-V-R-D-F-R-G-I-S-G-R-A-F-D-G-R-G-N-Y-N-I-G-V-K-E-Q-I-I-F-P-E-I-E-Y-D-K-I-D-A-L-R-G-L-N-I-S-I-T-T-T-A-K-T-D-D-E-A-K-A-L-L-T-A-F-S-F-P-F-R-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-N-N-I-R-K-G-D-E-V-I-V-L-T-G-R-D-K-K-R-R-G-T-V-L-A-R-V-D-A-D-H-V-L-V-E-G-V-N-V-V-K-K-H-V-K-A-N-P-M-A-N-N-P-G-G-I-V-E-K-T-M-P-I-H-V-S-N-V-A-L-F-N-P-A-T-G-K-G-D-R-V-G-V-Q-E-V-D-G-R-K-V-R-V-F-R-S-N-G-A-V-V-G-A-K-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-T-L-D-V-A-D-N-T-G-A-R-A-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-G-I-G-D-I-I-K-V-S-V-K-D-A-A-P-R-G-R-V-K-K-G-E-I-Y-N-A-V-V-V-R-T-A-K-G-V-R-R-K-D-G-S-L-I-R-F-G-G-N-A-A-V-L-L-N-A-K-L-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-R-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-T-Q-N-T-Q-V-A-K-R-Q-R-T-L-V-G-K-V-V-S-N-K-M-D-K-T-V-V-V-L-V-E-R-R-V-K-H-P-I-F-G-K-I-I-M-R-S-A-K-Y-K-A-H-D-E-S-N-Q-Y-N-E-G-D-T-V-E-I-A-E-G-R-P-I-S-R-S-K-A-W-R-V-V-R-L-V-E-A-A-R-V-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-S-R-R-K-Y-R-K-E-Q-K-G-R-N-T-G-L-A-S-R-G-T-H-V-S-F-G-E-F-G-L-K-A-T-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-I-N-R-H-I-K-R-G-G-R-I-W-I-R-I-F-P-D-K-P-I-S-Q-K-P-A-E-V-R-M-G-N-G-K-G-N-P-E-Y-W-V-A-E-I-Q-P-G-K-V-L-Y-E-M-E-G-V-S-E-E-L-A-R-E-A-F-R-L-A-A-A-K-L-P-I-S-T-T-F-V-A-R-H-I-G-A"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-T-A-I-I-R-G-V-H-I-S-A-Q-K-T-R-L-V-A-D-L-I-R-G-K-S-V-A-Q-A-L-N-I-L-T-F-S-P-K-K-A-A-V-I-L-K-K-A-V-E-S-A-I-A-N-A-E-H-N-D-G-A-D-I-D-E-L-K-V-T-T-I-F-V-D-K-A-Q-S-M-K-R-F-S-A-R-A-K-G-R-G-N-R-I-E-K-Q-T-C-H-I-T-V-K-V-G-A"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-I-K-K-G-P-F-V-D-A-H-L-I-K-K-V-D-A-A-V-A-G-K-D-K-K-P-I-K-T-W-S-R-R-S-T-V-L-P-E-F-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-I-Y-I-N-E-N-M-V-G-H-K-L-G-E-F-A-L-T-R-T-F-K-G-H-A-A-D-K-K-S-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-A-E-R-L-M-Q-V-I-L-A-P-I-V-T-E-K-A-T-F-V-A-E-K-N-Q-Q-V-A-F-R-V-V-A-D-A-T-K-P-E-I-K-A-A-V-E-L-L-F-K-V-Q-V-E-S-V-Q-V-L-N-R-K-G-K-V-K-R-F-G-R-F-V-G-R-R-R-N-E-R-K-A-Y-V-A-L-K-D-G-Q-E-I-D-F-A-E-V-K"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-N-Q-K-I-R-I-R-L-K-A-F-D-Y-K-L-I-D-Q-S-A-A-E-I-V-D-T-A-K-R-T-G-A-V-V-R-G-P-V-P-L-P-T-R-I-R-R-Y-D-V-L-R-S-P-H-V-N-K-T-S-R-D-Q-F-E-I-R-T-H-Q-R-L-M-D-I-V-D-P-T-D-K-T-V-D-A-L-M-R-L-D-L-P-A-G-V-D-V-E-I-A-L-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-E-V-P-K-R-E-I-L-P-D-P-K-F-G-S-V-E-L-A-K-F-M-N-V-V-M-L-D-G-K-K-A-V-A-E-R-I-I-Y-G-A-L-E-Q-V-Q-V-K-T-G-K-D-A-I-E-V-F-N-L-A-I-N-N-I-K-P-I-V-E-V-K-S-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-R-P-V-R-R-L-A-L-A-M-R-W-L-R-E-A-A-K-K-R-G-E-K-S-M-D-L-R-L-A-G-E-L-I-D-A-S-E-G-R-G-A-A-M-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-S-H-F-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-S-Q-L-V-R-K-P-R-E-V-S-I-I-K-S-K-S-P-A-L-E-N-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-V-R-L-T-N-G-Y-E-V-I-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-S-L-D-L-Q-G-V-K-D-R-K-Q-A-R-S-K-Y-G-A-K-R-P-K-K-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-Q-A-R-A-N-A-R-S-A-R-R-R-A-R-E-F-A-L-Q-G-V-Y-A-W-L-L-R-G-G-E-G-T-Q-D-A-G-E-I-D-A-H-L-R-D-A-E-D-F-S-E-A-D-A-Q-W-F-K-T-L-L-H-G-V-L-R-E-A-P-V-L-R-E-R-F-L-P-Y-I-D-R-P-L-A-E-L-S-P-V-E-H-G-I-L-L-I-G-S-F-E-L-M-H-H-V-E-V-P-Y-K-V-A-I-N-E-A-V-E-L-A-K-S-F-G-G-T-D-G-F-K-F-V-N-G-V-L-D-K-L-A-A-D-V-R-T-A-E-V-Q-A-A-P-R-R"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-N-P-Y-I-L-T-P-D-L-N-G-E-G-L-H-I-G-I-V-R-A-R-F-N-E-E-I-G-Q-A-Q-L-Q-A-C-L-E-E-L-G-K-L-G-V-D-E-R-D-V-M-V-V-S-V-P-G-A-L-E-L-G-V-A-L-A-R-M-A-E-S-Y-E-F-D-A-L-I-A-L-G-A-V-I-R-G-E-T-Y-H-F-E-V-V-S-N-E-S-A-A-A-I-S-R-I-A-L-E-T-G-I-P-V-A-N-G-V-L-T-V-D-T-D-E-Q-A-Q-A-R-A-A-G-K-G-A-D-C-A-Q-V-A-V-E-M-A-N-L-A-A-A-L-E-P-E-E-D-D-E-D-D-E-D-E-D-F-D-D-E-E-D-D-G-R"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-I-T-G-T-L-I-E-K-S-P-P-V-V-C-V-D-V-N-G-V-G-Y-E-I-D-V-P-M-S-T-L-Y-A-L-P-E-T-G-A-R-V-T-L-F-T-H-L-V-V-R-E-D-A-Q-L-L-Y-G-F-G-S-S-A-E-R-S-T-F-R-E-L-I-K-V-T-G-I-G-A-R-T-A-L-A-V-L-S-G-L-S-V-A-E-L-S-Q-A-I-T-L-Q-E-T-G-R-L-T-R-V-P-G-I-G-K-K-T-A-E-R-L-L-L-E-M-R-G-K-L-G-A-D-I-G-A-T-P-H-A-A-S-G-H-Q-S-D-I-L-N-A-L-L-A-L-G-Y-S-D-K-E-S-Q-A-A-L-K-K-L-P-D-G-V-D-V-S-E-G-I-R-L-A-L-K-A-L-V-R"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-L-D-R-E-G-Y-R-P-N-V-G-I-I-L-V-N-G-K-N-E-V-F-W-G-K-R-I-R-E-H-A-W-Q-F-P-Q-G-G-I-K-Y-G-E-S-P-V-Q-A-M-Y-R-E-L-H-E-E-V-G-L-K-P-E-H-V-R-I-L-G-R-T-R-D-W-L-R-Y-N-V-P-D-H-F-V-R-R-E-W-R-G-H-Y-K-G-Q-K-Q-I-W-F-L-L-R-L-V-G-R-D-S-D-V-C-L-R-A-T-Q-H-P-E-F-D-A-W-R-W-S-Q-Y-W-V-P-L-D-A-V-I-E-F-K-R-D-V-Y-T-Q-A-L-N-E-L-A-V-I-L-F-R-R-H-H-E-T-R-Y-L-R-Q-R-V-H-G-P-R-S-T-D-S-P-S-S-E-T-D-G-H-A-H-I-A-G"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-T-L-H-V-D-V-V-S-A-E-E-A-I-F-T-G-E-A-K-F-V-V-L-P-G-E-A-G-E-L-G-I-L-P-G-H-T-P-L-I-S-R-I-R-P-G-T-V-K-I-V-R-A-D-E-G-E-E-N-I-F-V-A-G-G-I-L-E-V-Q-P-G-S-V-T-V-L-A-D-T-A-I-R-A-A-D-L-D-E-A-R-A-V-A-A-R-E-K-A-E-E-A-L-R-N-A-K-D-K-A-D-I-A-V-V-E-A-E-L-A-M-L-A-A-Q-A-V-A-A-R-K-L-R-Q-G-R-T-H"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-L-S-T-V-A-R-P-Y-A-E-A-L-F-G-A-A-R-D-D-K-A-G-L-A-V-W-A-D-L-V-S-E-M-A-Q-V-A-A-N-P-D-V-R-E-A-M-A-D-P-R-L-D-D-K-Q-R-S-E-V-F-T-G-L-I-K-S-Q-L-P-Q-A-A-R-N-F-I-E-L-L-V-K-N-D-R-L-L-L-L-P-V-I-A-T-Q-F-V-A-L-K-N-R-H-E-G-T-A-Q-A-E-I-T-S-A-F-E-L-S-D-A-Q-V-K-E-L-I-A-A-L-E-L-K-F-G-L-K-L-K-P-H-V-S-V-D-Q-E-L-I-G-G-V-R-V-A-V-G-D-Q-V-L-D-T-S-V-K-A-Q-L-A-R-L-R-D-T-L-A-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-L-N-A-T-I-F-F-Q-M-L-V-F-F-V-L-G-W-F-T-M-K-F-V-W-P-P-L-T-K-A-I-D-E-R-R-Q-K-I-A-D-G-L-A-A-A-E-K-G-K-A-D-L-A-Q-A-Q-A-R-V-S-L-I-E-A-S-A-K-S-E-T-H-A-R-I-I-E-A-E-K-Q-A-A-S-M-I-E-Q-A-R-R-E-A-E-A-E-R-A-R-I-V-A-Q-A-A-Q-D-A-A-Q-E-V-Q-R-A-R-E-A-L-R-D-D-V-A-A-L-A-V-K-G-A-E-Q-I-L-K-R-E-V-D-A-R-A-H-A-E-L-L-N-Q-L-K-A-Q-L"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-F-L-S-F-L-L-G-Q-K-K-S-S-A-S-V-A-K-E-R-L-Q-I-I-L-A-H-E-R-G-R-G-D-S-P-D-Y-L-P-Q-L-Q-Q-E-L-V-A-V-I-S-K-Y-V-K-I-D-P-E-D-I-K-V-H-L-E-R-Q-D-T-L-E-V-L-E-V-K-I-E-M-P-Q-N"} +{"text": "### FUNCTION Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein ### SEQUENCE -M-S-A-C-P-A-P-R-S-P-V-R-W-L-H-A-F-T-L-F-L-L-L-A-V-L-A-G-C-V-S-V-P-K-P-M-A-G-A-G-E-D-V-F-S-R-V-G-R-F-A-I-T-V-T-E-S-D-G-K-Q-Q-A-V-Q-G-G-F-A-W-R-D-D-G-G-S-Y-L-L-D-L-T-N-P-L-G-S-T-E-A-R-V-E-G-R-P-G-M-A-V-L-T-R-A-N-G-E-R-L-A-A-E-H-P-D-A-L-A-E-D-A-L-G-S-P-V-P-V-T-G-L-R-D-W-L-R-G-R-L-M-A-G-A-A-P-D-G-L-E-R-D-A-Q-G-R-P-T-A-F-E-Q-D-G-W-N-A-R-L-S-R-Y-D-A-Q-G-P-Q-L-L-V-L-Q-R-Q-E-P-G-R-R-I-L-V-R-L-V-I-T-Q-P"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-G-R-I-S-L-I-V-A-A-L-L-M-L-S-A-I-S-L-V-T-S-R-Y-Q-S-R-Q-L-F-I-E-L-G-R-S-Q-A-E-A-R-D-L-D-T-N-W-R-R-L-Q-L-E-R-A-E-L-A-R-N-A-R-I-D-R-A-A-R-D-D-L-K-M-I-P-I-V-P-D-R-T-L-Y-M-N-Q-P-A-G-G-A-Q"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-V-A-K-P-H-E-V-K-R-D-W-F-V-I-D-A-K-G-K-V-L-G-R-V-A-S-E-V-A-H-R-L-R-G-K-H-K-P-E-F-T-P-H-V-D-T-G-D-Y-I-V-I-I-N-A-A-D-I-V-V-T-G-N-K-A-Q-D-K-K-Y-F-R-H-T-T-Y-P-G-G-I-R-E-T-N-F-E-K-M-Q-Q-R-F-P-G-R-A-I-Q-K-A-V-K-G-M-L-P-K-G-P-L-G-Y-A-M-I-K-K-L-K-V-Y-A-G-A-E-H-P-H-T-A-Q-Q-P-K-P-L-E-F"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters ### SEQUENCE -M-N-A-V-T-E-T-V-D-L-Q-A-P-P-P-V-P-L-V-F-T-D-S-A-A-A-K-V-K-D-L-L-A-E-E-G-N-P-E-L-K-L-R-V-F-V-Q-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-V-V-N-D-D-D-T-V-L-D-K-A-G-V-Q-L-L-V-D-P-M-S-F-Q-Y-L-V-G-A-E-I-D-Y-K-E-D-L-E-G-A-Q-F-V-I-R-N-P-N-A-S-T-T-C-G-C-G-S-S-F-S-V"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-F-C-G-N-A-D-T-Q-V-V-D-S-R-V-S-E-E-G-D-T-I-R-R-R-R-R-C-L-S-C-D-K-R-F-T-T-Y-E-R-V-E-L-A-M-P-S-V-V-K-R-D-G-S-R-T-E-Y-D-A-G-K-V-R-G-S-L-S-L-A-L-R-K-R-P-V-S-T-D-E-V-D-S-A-V-A-R-I-E-E-T-L-L-A-S-G-M-R-E-V-P-S-E-Q-I-G-E-L-V-M-G-E-L-K-R-L-D-K-V-A-Y-V-R-Y-A-S-V-Y-K-S-F-E-D-I-G-E-F-V-E-A-I-R-E-M-Q-G-P-L-L-P-G-K-K-L-R-K-D"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-S-S-K-Q-A-D-P-Q-T-D-A-R-P-L-P-Q-D-F-E-T-A-L-A-E-L-E-S-L-V-S-A-M-E-N-G-T-L-P-L-E-Q-S-L-S-A-Y-R-R-G-V-E-L-A-R-V-C-Q-D-R-L-A-Q-A-E-Q-Q-V-K-V-L-E-G-D-L-L-R-P-L-D-P-A-A-L-D-D-E"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-V-V-F-I-V-H-P-D-Q-S-E-Q-V-P-A-M-V-E-R-Y-Q-A-L-V-T-G-Q-S-G-T-V-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-Q-K-L-V-K-A-H-Y-V-C-M-N-I-E-C-G-Q-A-T-L-D-E-L-E-H-S-F-R-Y-N-D-A-V-L-R-H-L-V-I-K-T-K-K-A-P-A-A-P-S-I-M-M-K-S-V-E-R-E-E-A-R-K-A-S-A-E-A-A-A-T-A-T-A-A-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-F-F-G-K-R-K-E-K-R-K-F-T-Q-Q-N-P-L-F-K-R-R-K-F-C-R-F-T-A-A-G-V-E-E-I-D-Y-K-D-L-D-T-L-R-D-F-V-Q-E-N-G-K-I-I-P-A-R-L-T-G-T-R-A-I-Y-Q-R-Q-L-D-T-A-I-K-R-A-R-F-L-A-L-L-P-Y-T-D-N-H-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-E-K-V-A-N-L-G-N-L-G-E-V-V-R-V-R-D-G-Y-A-R-N-F-L-I-P-Q-K-K-A-R-R-A-T-D-A-A-L-K-E-F-E-A-R-R-A-E-L-E-K-V-Q-A-E-K-L-A-A-A-Q-A-L-A-E-R-L-N-G-F-Q-L-K-I-S-Q-K-A-G-V-D-G-R-L-F-G-S-V-T-N-A-D-V-A-E-G-L-R-K-A-G-F-E-A-V-E-K-S-Q-V-R-M-P-N-G-Q-I-K-A-V-G-E-Y-L-V-Q-A-V-L-H-A-D-V-V-A-D-V-V-V-L-V-E-G-E-M-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-A-Q-A-R-K-R-A-R-Q-S-V-Q-R-N-K-H-N-S-S-L-R-S-M-L-R-T-A-I-K-R-V-R-Q-S-I-A-T-G-D-K-A-A-A-G-E-T-L-R-K-A-T-S-V-I-D-S-V-A-D-K-N-I-I-H-K-N-K-A-A-R-H-K-S-R-L-A-A-A-V-K-A-L-A"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-S-T-L-D-T-Q-H-D-V-V-V-E-K-Q-P-A-R-T-A-P-P-P-M-Y-Q-V-V-L-L-N-D-D-Y-T-P-M-E-F-V-V-K-V-L-Q-K-F-F-G-K-N-S-E-D-A-T-R-I-M-L-Q-V-H-H-E-G-R-A-V-C-G-V-Y-P-R-D-L-A-A-T-R-I-A-Q-V-S-Q-Y-A-R-A-R-Q-H-P-L-Q-C-I-M-E-P-T"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-A-N-E-N-R-L-V-W-L-D-M-E-M-T-G-L-D-P-E-K-E-R-I-I-E-V-A-V-V-V-T-E-A-D-L-T-V-V-A-E-G-P-V-L-V-V-H-Q-P-D-S-L-L-D-A-M-D-N-W-N-K-S-T-H-G-K-S-G-L-I-E-K-V-K-A-S-T-L-G-E-A-Q-A-E-Q-I-L-L-E-F-L-A-E-H-V-P-A-G-K-S-P-L-C-G-N-T-I-S-Q-D-R-R-F-M-Y-A-Y-M-P-N-L-E-R-F-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-A-R-R-W-A-P-A-V-Y-K-G-F-D-K-K-S-R-H-E-A-L-A-D-I-Y-E-S-I-D-E-L-K-Y-Y-R-E-H-L-L-K-V"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-S-V-D-L-K-I-L-D-A-R-M-R-E-Y-L-P-A-Y-A-T-P-G-S-A-G-L-D-L-R-A-C-T-E-A-S-L-V-I-E-P-G-Q-T-V-L-V-P-T-G-L-A-I-H-I-G-D-P-R-Y-A-A-M-I-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-Q-L-M-V-S-T-W-N-R-G-T-Q-P-F-T-L-D-P-M-E-R-L-A-Q-L-V-I-V-P-V-Q-Q-V-A-F-N-V-V-E-D-F-D-A-S-E-R-G-A-G-G-F-G-S-T-G-R-G"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-R-A-R-H-K-K-V-I-A-A-A-K-G-Y-R-G-R-R-G-N-V-F-R-I-A-K-Q-A-V-M-R-A-G-Q-Y-A-Y-R-D-R-R-N-K-K-R-T-F-R-A-L-W-I-T-R-I-N-A-A-V-R-E-Q-G-M-S-Y-S-V-F-I-A-G-L-K-K-A-A-I-E-L-D-R-K-V-L-A-D-L-A-V-R-D-K-A-G-F-A-A-I-V-Q-Q-A-K-A-A-L-A-A"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-G-T-T-M-L-A-E-P-R-T-L-T-K-A-E-L-A-E-L-L-F-E-R-V-G-L-N-K-R-E-A-K-D-I-V-D-T-F-F-E-E-I-R-D-A-L-A-R-G-D-S-V-K-L-S-G-F-G-N-F-Q-V-R-D-K-P-P-R-P-G-R-N-P-K-T-G-E-T-I-P-I-A-A-R-R-V-V-T-F-H-A-S-Q-K-L-K-S-V-V-E-Q-P-N-S-P-P-D-P-A-S-A-E"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-A-P-Q-E-P-V-D-S-T-P-E-S-G-E-N-A-A-T-P-G-L-E-D-D-L-S-A-E-L-A-A-L-R-A-E-L-E-A-A-Q-A-T-V-K-A-Q-Q-E-Q-V-L-R-A-A-A-E-A-E-N-V-R-R-R-A-Q-E-D-V-A-K-A-R-K-F-G-I-E-S-F-A-E-S-L-V-P-V-K-D-S-L-E-A-A-L-A-Q-P-D-Q-A-A-Q-A-W-R-E-G-V-E-V-T-L-K-Q-L-T-A-A-F-E-R-N-L-L-K-E-I-A-P-A-Q-G-D-K-F-D-P-H-L-H-Q-A-I-S-S-V-P-A-D-Q-P-A-N-T-V-L-Q-L-L-Q-K-G-Y-V-I-A-D-R-T-L-R-P-A-L-V-V-V-S-A-G-Q-G"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-P-A-I-P-P-K-L-I-L-A-S-S-S-R-Y-R-R-E-L-L-S-R-L-R-L-P-F-T-A-I-S-P-D-V-D-E-T-P-Q-P-G-E-A-P-A-D-L-A-L-R-L-S-V-A-K-A-M-A-V-A-A-T-H-P-G-S-V-V-I-G-S-D-Q-V-A-T-V-D-G-E-P-I-G-K-P-G-G-F-E-R-A-R-E-Q-L-R-R-L-S-G-R-A-V-E-F-H-S-A-M-A-V-T-D-G-V-H-T-E-T-A-D-I-V-T-L-C-R-F-R-T-L-T-D-A-A-I-D-A-Y-L-R-A-E-E-P-Y-D-T-A-G-S-A-K-A-E-S-L-G-I-A-L-M-D-S-I-R-S-D-D-P-T-A-I-I-G-L-P-L-I-A-L-T-R-M-L-G-R-F-G-L-D-P-L-T-G-H-P-A"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-E-S-I-E-Q-R-V-K-K-I-V-A-E-Q-L-G-V-N-E-A-E-I-K-N-E-S-S-F-L-D-D-L-G-A-D-S-L-D-M-V-E-L-V-M-A-L-E-D-E-F-E-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-Q-A-I-D-Y-I-N-S-H-G-K-Q"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-L-L-F-L-V-L-L-V-L-L-G-L-I-Q-Y-P-L-W-L-G-K-G-G-W-F-K-V-W-D-L-Q-R-Q-V-A-E-Q-R-E-T-N-D-G-L-R-A-R-N-T-A-L-E-A-E-V-R-D-L-A-T-G-V-G-A-V-E-E-R-A-R-S-E-L-G-M-M-R-E-G-E-V-F-V-H-I-L-P-P-G-T-P-L-P-S-D-N-S-T-P-Q-A-S-A-L-S-K-P-R-P-P-A-T-P-P-R-R"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-L-I-V-A-A-V-G-T-R-M-P-G-W-V-E-T-A-W-D-D-Y-A-K-R-L-P-A-D-C-A-L-E-L-R-E-I-K-P-E-P-R-T-S-G-K-T-P-A-Q-M-M-A-A-E-A-R-R-I-E-T-A-L-P-P-G-V-L-R-I-A-L-D-E-R-G-R-D-L-T-T-V-A-L-S-Q-Q-L-E-K-W-R-A-G-G-R-D-V-A-F-L-V-G-G-P-D-G-L-D-A-A-L-K-A-S-C-E-G-L-L-R-L-S-S-L-T-L-P-H-P-M-V-R-V-L-L-A-E-Q-L-Y-R-A-W-A-I-M-T-N-H-P-Y-H-R-A"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-G-V-T-R-I-G-L-L-G-G-S-F-D-P-V-H-V-A-H-I-A-L-A-D-T-A-R-Q-F-L-G-L-D-Q-V-Q-L-I-P-A-A-N-P-W-Q-R-Q-P-L-K-A-S-A-P-H-R-L-R-M-L-E-L-A-I-A-G-H-P-A-L-A-I-N-P-V-E-I-E-R-G-G-A-T-Y-T-A-D-T-V-R-A-L-P-G-G-P-Q-Y-F-W-L-L-G-T-D-Q-L-Q-N-F-C-T-W-R-D-W-Q-D-I-A-A-R-I-E-L-A-V-A-T-R-P-G-A-S-I-A-P-P-A-E-L-A-A-W-L-A-A-H-R-R-Q-L-H-E-L-P-F-A-P-M-A-V-S-A-S-D-I-R-Q-R-L-A-A-G-A-A-T-D-G-L-L-P-E-P-V-A-A-Y-I-A-T-H-H-L-Y-R"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-S-N-K-G-Q-T-L-Q-D-P-F-L-N-T-L-R-K-E-H-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-Y-V-V-L-L-R-N-T-V-T-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-A-V-N-F-Q-V-E-V-P-A-E"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-S-S-V-S-A-A-G-A-T-P-P-A-S-P-G-C-I-A-G-I-G-M-D-L-L-R-I-E-R-I-E-R-A-L-A-R-H-G-D-R-F-A-Q-K-I-L-G-P-K-E-L-A-K-F-Q-A-R-R-R-R-D-P-A-R-G-V-R-F-L-A-T-R-F-A-A-K-E-A-F-S-K-A-I-G-L-G-M-R-M-P-M-S-W-R-R-V-Q-T-L-N-A-P-G-G-R-P-V-L-V-I-G-A-E-L-A-D-W-F-D-A-R-F-G-A-A-H-V-S-I-T-D-E-S-D-M-A-A-A-Y-V-I-V-E-R-K-P-A-P-D-G-R-P"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-T-A-Q-E-L-R-V-G-N-V-I-M-V-G-K-D-P-L-V-V-Q-K-T-E-Y-N-K-S-G-R-N-A-A-V-V-K-L-K-F-K-N-L-L-T-G-S-G-S-E-S-V-Y-K-A-D-E-K-F-D-V-V-V-L-E-R-K-E-C-T-Y-S-Y-F-G-D-P-M-Y-V-F-M-D-E-E-Y-N-Q-Y-E-I-E-A-D-S-M-G-D-A-L-N-Y-L-E-E-A-M-P-V-E-V-V-F-Y-D-G-R-A-I-S-V-E-L-P-T-I-L-V-R-E-I-T-Y-T-E-P-A-V-R-G-D-T-S-G-K-V-L-K-P-A-K-I-N-T-G-F-E-L-S-V-P-L-F-C-A-I-G-D-K-I-E-I-D-T-R-T-N-E-Y-R-S-R-V-N"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-A-A-D-D-H-F-S-L-F-G-L-P-T-R-F-A-L-D-P-V-Q-L-E-Q-A-W-R-A-V-A-A-R-V-H-P-D-R-Y-A-T-A-S-A-A-E-R-R-V-A-M-Q-W-A-A-R-A-N-E-A-Y-R-Q-L-R-D-P-M-L-R-A-R-Y-L-C-E-Q-A-G-V-D-L-Q-T-E-S-N-T-A-M-D-P-A-F-L-M-Q-Q-M-E-W-R-E-M-L-D-D-A-R-R-D-P-A-A-F-A-A-L-R-A-E-L-E-Q-A-R-L-R-M-Q-Q-T-L-S-E-L-I-D-E-R-G-D-Y-Q-Q-A-G-T-K-V-R-E-W-M-F-V-E-K-L-A-Q-E-L-S-A-A-Q-P-M-Q"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-V-E-D-C-L-N-Q-I-P-N-R-F-K-L-T-L-A-A-T-Y-R-A-R-E-L-V-Q-G-H-A-P-R-L-D-S-K-D-K-P-T-V-T-A-L-R-E-I-A-S-G-L-T-G-L-E-M-L-R-K-V-P-T"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-K-G-Q-L-A-G-L-M-R-Q-A-Q-Q-M-Q-E-N-M-K-K-A-Q-D-A-L-A-E-I-Q-V-E-G-A-A-G-G-G-L-V-K-V-T-M-T-C-R-H-D-V-K-R-V-A-I-D-A-S-L-L-G-E-D-K-D-M-L-E-D-L-V-A-A-A-F-N-D-A-L-R-K-A-E-A-T-S-Q-E-K-M-A-S-V-T-A-G-M-P-L-P-P-G-M-K-L-P-F"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-R-L-I-G-L-D-G-E-Q-L-G-I-V-K-I-A-D-A-F-R-L-S-E-Q-S-D-V-D-L-V-E-I-A-P-N-A-D-P-P-V-C-R-L-M-D-Y-G-K-F-K-Y-Q-E-Q-K-R-Q-A-E-A-R-S-K-Q-K-V-I-Q-V-K-E-V-K-F-R-P-A-T-D-E-G-D-Y-Q-V-K-L-R-N-L-R-R-F-L-E-E-G-D-K-A-K-V-T-L-R-F-R-G-R-E-M-A-H-Q-E-L-G-M-R-V-L-E-R-V-R-D-D-L-I-E-L-A-Q-V-E-A-M-P-K-L-E-G-R-Q-M-V-M-V-L-A-P-R-K-K-A-V-G-K-P-D-A-A-G"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-I-I-D-N-R-K-A-T-H-D-Y-F-I-E-D-R-Y-E-A-G-M-V-L-E-G-W-E-V-K-A-I-R-D-G-R-V-Q-L-K-E-S-Y-V-I-V-R-D-G-E-I-Y-L-L-G-M-H-V-S-P-L-P-T-A-S-T-H-I-R-P-D-A-T-R-T-R-K-L-L-L-K-A-E-E-I-R-K-L-I-G-K-V-E-Q-R-G-Y-T-L-V-P-L-N-L-H-Y-K-N-G-R-I-K-L-D-F-A-L-G-R-G-K-K-L-Y-D-K-R-D-T-A-R-E-K-D-W-Q-R-E-K-E-R-V-L-K-H-D-T-R-V-N-Q-R-D-S"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-V-A-D-I-R-K-S-A-E-T-R-M-A-K-S-L-E-T-L-K-A-S-L-A-K-I-R-T-G-R-A-H-T-G-I-L-D-H-V-Q-V-E-Y-Y-G-S-P-V-P-I-S-Q-V-A-N-V-N-L-V-D-A-R-T-I-S-V-Q-P-Y-E-K-S-M-A-G-P-I-E-K-A-I-R-E-S-D-L-G-L-N-P-V-S-M-G-E-T-I-R-V-P-M-P-A-L-T-E-E-R-R-R-D-L-T-K-V-V-K-S-E-G-E-D-A-K-V-A-V-R-N-L-R-R-E-A-N-E-A-L-K-K-L-V-K-D-K-E-I-S-E-D-D-E-R-R-A-Q-D-D-V-Q-K-L-T-D-R-A-V-G-D-I-D-K-M-I-V-Q-K-E-A-E-I-M-T-V"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-R-H-K-S-K-S-I-P-G-R-N-L-R-L-A-D-Q-I-Q-K-D-L-A-G-I-I-Q-R-E-I-D-M-T-R-A-G-L-I-T-L-S-G-V-E-L-S-A-D-Y-A-H-A-K-V-Y-F-T-V-L-G-A-E-P-D-T-A-A-A-L-L-N-E-K-A-G-W-L-H-S-Q-L-Y-K-L-L-H-I-H-T-V-P-T-L-R-F-V-H-D-P-Q-I-T-R-G-I-E-M-S-V-L-I-D-R-A-N-R-P-G-P-H-S-G-V-P-D-E-P-E-D-Q-S"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-D-L-F-A-L-T-E-E-A-L-A-G-M-D-I-E-L-V-D-V-E-R-A-A-M-G-L-L-R-V-T-I-D-R-V-D-G-V-R-I-E-D-C-E-Q-V-S-R-Q-L-S-R-V-Y-E-V-E-N-I-D-Y-K-R-L-E-V-G-S-P-G-V-D-R-P-L-R-N-E-A-E-F-R-R-F-A-G-E-R-I-E-I-K-L-R-E-A-L-D-G-R-K-V-F-S-G-T-L-R-A-P-E-A-D-G-A-S-G-Q-D-D-T-A-G-A-G-K-A-V-F-G-L-E-F-E-A-K-K-N-D-I-Q-V-L-S-F-T-L-D-D-I-E-R-A-K-L-D-P-V-L-D-F-K-G-K-K-R"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-T-E-L-S-L-S-V-Q-Y-G-V-A-D-A-R-L-P-R-W-R-L-R-R-W-V-Q-Y-A-L-A-G-A-A-G-D-G-H-A-G-L-A-G-A-E-L-G-L-R-L-V-G-L-A-E-G-R-R-L-N-R-E-F-R-G-R-D-Y-A-T-N-V-L-T-F-E-Y-G-T-G-P-D-G-V-A-R-G-D-I-V-V-C-V-P-V-L-A-R-E-A-R-E-Q-R-K-T-L-L-D-H-A-A-H-L-T-V-H-G-T-L-H-A-L-G-Y-D-H-I-K-A-G-E-A-R-R-M-E-A-L-E-T-A-V-L-A-R-M-G-I-A-D-P-Y-L-A-A"} +{"text": "### FUNCTION Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-K-T-A-D-S-S-L-L-A-D-I-R-E-V-N-L-S-Y-L-L-L-A-Q-R-M-L-R-D-D-Y-A-A-S-M-F-R-L-G-F-S-N-E-V-A-D-I-L-M-R-L-S-P-A-Q-L-V-K-L-A-N-S-S-S-L-L-C-R-F-R-F-D-D-Y-S-L-L-S-A-L-T-Q-D-V-L-G-G-A-L-Q-Q-A-H-A-T-I-L-L-A-R-Q-P-V-E-E-L-A"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-L-I-E-L-N-G-I-V-D-E-V-L-P-D-S-R-Y-R-V-K-L-D-N-G-I-E-V-G-A-Y-A-S-G-R-M-R-K-H-R-I-R-I-L-A-G-D-R-V-T-L-E-M-S-P-Y-D-L-T-K-G-R-I-N-F-R-H-K-D-E-R-S-G-P-P-S-R-P-P-Q-H-R-R"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-T-T-P-I-P-L-A-R-G-W-L-P-A-A-P-S-T-L-D-P-L-R-K-Y-W-L-F-R-P-G-A-L-T-A-G-L-R-Q-L-G-H-V-R-L-R-V-L-A-E-Y-P-T-G-A-P-R-D-E-A-D-G-M-R-I-A-A-Q-S-P-V-W-V-R-E-V-L-M-S-I-D-G-V-D-S-V-V-A-R-S-L-T-P-L-R-A-S-H-G-V-W-Q-G-M-R-R-L-L-T-R-P-L-A-D-M-L-Y-H-D-P-G-I-H-R-S-V-F-V-C-R-R-L-A-A-G-V-P-F-H-A-T-A-I-A-R-A-P-A-G-G-P-E-P-A-L-W-A-R-R-S-A-F-W-R-A-G-Q-P-L-L-V-A-E-C-F-L-P-A-F-W-S-L-A-R-A-P-V-A-P-R"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-L-I-A-I-L-E-Q-E-E-I-A-R-L-T-G-G-N-A-V-T-E-F-A-P-G-D-T-V-V-V-S-V-N-V-V-E-G-T-R-K-R-V-Q-A-F-E-G-V-V-I-A-K-R-N-R-G-L-N-S-S-F-I-V-R-K-I-S-S-G-E-A-V-E-R-T-F-Q-L-Y-S-P-Q-I-A-G-I-E-V-K-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-S-R-S-G-K-S-A-R-I-K-E-K-L-V-L-K-K-A-K-S-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-V-A-D-I-K-K-S-E-I-V-A-Q-F-Q-R-A-Q-G-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-R-I-N-E-L-T-G-H-F-K-E-H-M-K-D-H-H-S-R-R-G-L-L-R-M-V-S-R-R-R-K-L-L-D-Y-L-K-G-R-N-P-D-S-Y-R-A-L-I-E-K-L-G-L-R-K"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-K-T-G-G-K-Q-Y-R-V-A-T-G-E-K-L-K-V-E-Q-I-P-A-D-I-G-Q-E-I-T-L-D-Q-V-L-S-V-G-E-G-D-Q-L-K-V-G-T-P-L-V-S-G-A-V-V-K-A-T-V-L-A-H-G-R-H-D-K-I-K-I-F-K-M-R-R-R-K-H-Y-Q-K-H-Q-G-H-R-Q-N-Y-T-E-I-R-I-E-A-I-T-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-E-E-T-L-L-A-F-D-F-G-E-K-K-I-G-I-A-I-G-N-T-L-T-R-Q-A-R-P-L-E-I-I-F-S-E-T-R-A-A-R-F-G-R-I-G-Q-L-L-Q-E-W-Q-P-Q-R-A-V-V-G-L-P-L-T-L-D-G-Q-E-Q-P-A-S-A-R-A-R-R-F-A-N-Q-L-H-G-H-F-G-L-A-V-E-L-V-D-E-R-S-S-S-M-E-A-Q-Q-L-L-G-T-H-A-D-D-D-A-V-A-A-A-V-I-L-Q-R-Y-L-D-T-L-S-Q-P"} +{"text": "### FUNCTION Dephosphorylates the 5' and 2'-phosphates of deoxyribonucleotides ### SEQUENCE -M-L-I-L-L-D-Q-D-G-V-L-A-D-F-E-H-A-F-I-D-A-W-R-K-R-H-P-D-I-E-P-V-A-F-E-E-R-K-S-F-H-I-R-E-D-Y-A-P-E-L-R-G-L-A-E-A-I-Y-T-A-P-G-F-I-R-D-L-P-P-V-P-G-A-V-E-A-F-R-E-L-L-A-L-G-M-D-V-R-I-C-S-S-P-L-M-Q-F-E-N-C-V-A-E-K-Y-L-W-V-E-R-H-L-G-R-D-A-T-Q-R-L-I-L-T-R-D-K-T-L-V-Q-G-D-L-L-I-D-D-R-P-V-I-T-G-A-A-R-P-R-W-R-H-I-I-Y-D-A-P-Y-N-R-D-Q-T-D-R-P-R-L-D-W-R-N-W-R-N-V-L-A-G-E-L-Y-R-S-D-A"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-K-A-T-G-F-I-K-E-F-R-D-F-A-V-K-G-N-A-I-D-L-A-V-G-V-I-I-G-A-A-F-G-K-I-V-D-S-L-V-K-D-V-V-M-P-L-V-N-F-I-L-G-G-S-V-D-F-S-N-K-F-L-V-L-S-M-P-D-G-Y-T-G-P-M-T-Y-A-D-L-T-K-A-G-A-N-V-L-A-W-G-N-F-I-T-I-I-I-N-F-V-L-L-A-F-V-I-F-W-M-V-K-A-I-Y-F-A-R-R-K-E-E-A-A-P-E-A-P-A-A-P-P-E-D-V-T-V-L-R-E-I-R-D-L-L-K-D-K-Q-G-S"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-Q-T-D-Y-A-E-L-V-R-R-T-I-R-S-V-P-D-W-P-T-P-G-V-T-F-R-D-I-T-P-V-L-Q-D-P-R-T-F-R-V-L-I-D-L-F-V-Y-R-Y-M-R-Q-R-L-D-L-V-A-G-V-D-A-R-G-F-I-V-G-A-V-L-A-H-E-L-N-L-G-F-V-P-V-R-K-K-S-K-L-P-Y-R-T-V-A-E-E-Y-S-L-E-Y-G-N-A-A-V-E-M-H-T-D-S-V-R-T-G-Q-R-V-L-L-V-D-D-L-I-D-T-G-G-T-M-L-A-A-I-K-L-L-Q-R-L-G-A-N-V-V-E-A-A-A-I-I-D-L-P-Y-L-G-G-S-A-Q-I-T-A-T-G-T-P-L-Y-T-V-C-Q-Y-Q-E-G-D"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-L-P-T-D-R-K-Y-T-E-S-H-E-W-V-Q-A-E-G-D-V-F-V-V-G-I-T-D-N-A-Q-E-Q-L-G-D-L-V-F-V-G-D-V-K-V-G-A-T-L-K-A-G-E-T-A-G-V-V-E-S-V-K-A-A-S-D-I-Y-A-P-V-D-G-E-I-V-A-F-N-D-E-L-E-A-N-P-S-L-I-N-E-S-A-Y-T-A-W-I-F-K-I-K-P-A-N-A-A-D-L-D-K-L-L-D-A-A-G-Y-Q-A-V-A-G"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-H-A-I-L-K-M-G-D-P-R-L-L-R-V-A-A-P-V-E-R-Y-D-T-P-E-L-R-A-L-I-D-D-M-F-E-T-M-A-H-A-Q-G-V-G-L-A-A-P-Q-I-G-V-D-L-Q-L-V-I-F-G-F-E-R-N-D-R-Y-P-D-A-P-A-V-P-R-T-I-L-C-N-P-V-I-E-P-L-S-D-E-M-E-D-G-W-E-G-C-L-S-V-P-G-L-R-G-L-V-P-R-Y-R-H-I-R-Y-S-G-Y-D-P-A-G-Q-R-I-E-R-E-A-E-G-F-H-A-R-V-V-Q-H-E-C-D-H-L-I-G-R-L-Y-P-T-R-I-R-D-L-T-K-F-G-Y-T-E-V-L-F-P-E-M-D-P-N-A-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-S-K-A-E-I-L-D-A-I-A-G-M-S-V-L-E-L-S-E-L-I-K-E-M-E-E-K-F-G-V-S-A-A-A-A-A-V-A-V-A-A-P-A-A-G-G-A-G-A-A-A-A-E-E-Q-T-E-F-T-V-V-L-L-E-A-G-A-N-K-V-S-V-I-K-A-V-R-E-L-T-G-L-G-L-K-E-A-K-D-L-V-D-G-A-P-K-P-V-K-E-A-L-P-K-A-D-A-E-A-A-K-K-K-L-E-E-A-G-A-K-V-E-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-L-N-R-Q-E-K-A-V-V-I-E-E-V-S-A-Q-V-A-K-A-Q-S-I-V-I-A-E-Y-R-G-L-D-V-A-S-V-T-V-L-R-K-T-A-R-E-S-G-V-Y-L-R-V-L-K-N-T-L-V-R-R-A-V-A-G-T-A-F-E-P-L-S-E-Q-L-T-G-P-L-I-Y-G-I-S-A-D-P-V-A-A-A-K-V-L-A-G-F-A-K-S-N-D-K-L-V-I-K-A-G-S-L-P-N-S-L-L-T-Q-D-G-V-K-A-L-A-T-M-P-S-R-E-E-L-L-S-K-L-L-G-T-M-Q-A-P-I-A-Q-F-V-R-T-L-N-E-V-P-T-K-F-A-R-G-L-A-A-V-R-D-Q-K-A-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-V-G-F-I-K-L-Q-V-P-A-G-K-A-N-P-S-P-P-I-G-P-A-L-G-Q-R-G-L-N-I-M-E-F-C-K-A-F-N-A-K-T-Q-G-M-E-L-G-L-P-I-P-V-V-I-T-A-F-A-D-K-S-F-T-F-I-M-K-T-P-P-A-T-V-L-I-K-K-A-S-G-V-Q-K-G-S-A-K-P-H-T-D-K-V-G-T-L-T-R-A-Q-A-E-E-I-A-K-T-K-Q-P-D-L-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-I-T-V-E-G-G"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-Q-A-R-A-N-A-R-S-A-R-R-R-A-R-E-F-A-L-Q-G-V-Y-A-W-L-L-R-G-G-E-G-T-Q-D-A-G-E-I-D-A-H-L-R-D-A-E-D-F-S-E-A-D-A-Q-W-F-K-T-L-L-H-G-V-L-R-E-A-P-V-L-R-E-R-F-L-P-Y-I-D-R-P-L-A-E-L-S-P-V-E-H-G-I-L-L-I-G-S-F-E-L-M-H-H-V-E-V-P-Y-K-V-A-I-N-E-A-V-E-L-A-K-S-F-G-G-T-D-G-F-K-F-V-N-G-V-L-D-K-L-A-A-D-V-R-T-A-E-V-Q-A-A-P-R-R"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-N-P-Y-I-L-T-P-D-L-N-G-E-G-L-H-I-G-I-V-R-A-R-F-N-E-E-I-G-Q-A-Q-L-Q-A-C-L-E-E-L-G-K-L-G-V-D-E-R-D-V-M-V-V-S-V-P-G-A-L-E-L-G-V-A-L-A-R-M-A-E-S-Y-E-F-D-A-L-I-A-L-G-A-V-I-R-G-E-T-Y-H-F-E-V-V-S-N-E-S-A-A-A-I-S-R-I-A-L-E-T-G-I-P-V-A-N-G-V-L-T-V-D-T-D-E-Q-A-Q-A-R-A-A-G-K-G-A-D-C-A-Q-V-A-V-E-M-A-N-L-A-A-A-L-E-P-E-E-D-D-E-D-E-D-D-E-D-E-D-F-D-D-E-E-D-D-G-R"} +{"text": "### FUNCTION Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein ### SEQUENCE -M-S-V-C-P-A-P-R-S-P-V-R-W-L-H-A-F-T-L-C-L-L-L-A-V-L-A-G-C-V-S-V-P-K-P-M-A-G-A-G-E-D-V-F-S-R-V-G-R-F-A-I-T-V-T-E-S-D-G-K-Q-Q-A-V-Q-G-G-F-A-W-R-D-D-G-G-S-Y-L-L-D-L-T-N-P-L-G-S-T-E-A-R-V-E-G-R-P-G-M-A-V-L-T-R-A-N-G-E-R-L-A-A-E-H-P-D-A-L-A-E-D-A-L-G-S-P-V-P-V-T-G-L-R-D-W-L-R-G-R-L-M-A-G-A-A-P-D-G-L-E-R-D-A-Q-G-R-P-T-A-F-E-Q-D-G-W-N-A-R-L-S-R-Y-D-A-Q-G-P-Q-L-L-V-L-Q-R-Q-E-P-G-R-R-I-L-V-R-L-V-I-T-Q-P"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-K-T-G-G-K-Q-Y-R-V-A-T-G-E-K-L-K-V-E-Q-I-P-A-D-I-G-Q-E-I-T-L-D-Q-V-L-S-V-G-E-G-D-Q-L-K-V-G-T-P-L-V-S-G-A-V-V-K-A-T-V-L-A-H-G-R-H-D-K-I-K-I-F-K-M-R-R-R-K-H-Y-Q-K-H-Q-G-H-R-Q-N-Y-T-E-I-R-I-E-A-I-T-A"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-A-D-Q-D-Q-T-N-Q-Q-A-G-S-D-A-P-S-F-N-L-Q-R-V-Y-L-K-D-L-S-L-E-M-P-N-A-P-H-V-F-L-E-Q-E-A-P-Q-V-E-V-S-I-N-V-G-G-Q-R-L-A-E-T-V-F-E-S-T-V-T-V-T-V-T-T-R-V-N-D-K-V-L-Y-L-V-E-G-T-Q-A-G-I-F-E-L-A-N-I-P-A-E-Q-M-D-P-L-L-G-I-V-C-P-T-M-L-Y-P-Y-L-R-A-N-V-A-D-A-I-T-R-T-S-L-P-A-L-H-L-A-E-V-N-F-Q-A-L-Y-E-Q-R-L-A-E-M-A-Q-Q-Q-P-D-A-A-N-G-N-D-S-G-I-I-L-P-P-G-A-T-R-Q"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-L-L-S-I-L-R-Y-P-D-P-R-L-H-K-T-A-K-P-V-A-V-V-D-D-R-I-R-Q-L-V-R-D-M-A-D-T-M-Y-D-A-P-G-V-G-L-A-A-T-Q-V-D-V-H-E-R-V-V-V-I-D-V-S-E-E-G-N-D-L-R-V-L-I-N-P-E-I-T-W-K-S-D-E-R-Q-T-Y-E-E-G-C-L-S-V-P-G-I-Y-D-E-V-E-R-A-A-R-I-R-C-K-A-L-D-Q-Q-G-Q-P-Y-E-F-E-A-D-G-L-L-A-V-C-V-Q-H-E-I-D-H-L-D-G-K-V-F-V-E-Y-L-S-N-L-K-Q-N-R-I-K-T-K-L-K-K-A-E-R-E-A-E-R-A"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-T-E-T-E-F-L-A-L-V-D-Q-V-L-D-S-I-E-S-Q-A-D-D-W-A-A-G-L-D-V-D-I-E-A-T-R-S-G-N-V-L-T-L-V-F-E-D-G-T-Q-V-V-V-N-A-Q-A-A-M-Q-E-L-W-V-A-A-R-S-G-G-F-H-Y-R-Y-D-G-Q-H-W-N-D-T-R-G-G-P-R-L-P-D-A-L-S-Q-I-C-S-E-A-A-G-V-P-V-S-V-R-L"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-A-S-T-S-G-A-S-R-V-R-K-K-V-K-K-N-V-S-D-G-I-A-H-V-H-A-S-F-N-N-T-I-I-T-I-T-D-R-Q-G-N-A-L-S-W-A-T-S-G-G-A-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-T-A-G-R-V-A-M-E-Y-G-I-K-T-L-E-V-R-I-K-G-P-G-P-G-R-E-S-S-V-R-A-L-N-A-L-G-I-K-I-S-S-I-A-D-I-T-P-V-P-H-N-G-C-R-P-P-K-R-R-R-I"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-P-Q-Q-H-A-E-I-G-L-T-A-I-F-G-I-G-R-T-R-A-R-K-I-C-E-A-A-G-V-P-V-T-K-K-V-K-D-L-T-D-A-E-L-E-R-I-R-E-H-I-G-V-F-A-V-E-G-D-L-R-R-E-V-Q-L-S-I-K-R-L-I-D-L-G-T-Y-R-G-M-R-H-K-R-G-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-R-A-A-A-S-L-K-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-V-I-Q-M-Q-G-E-V-L-E-N-L-P-N-A-T-F-R-V-K-L-E-N-G-H-V-V-L-G-H-I-S-G-K-M-R-M-H-Y-I-R-I-L-P-G-D-K-V-T-V-E-L-T-P-Y-D-L-T-R-A-R-I-V-F-R-S-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-S-D-I-Q-L-N-T-L-K-P-A-E-G-S-K-H-A-K-R-R-V-G-R-G-I-G-S-G-L-G-K-T-A-G-R-G-H-K-G-Q-K-S-R-S-G-G-F-H-K-V-G-F-E-G-G-Q-M-P-L-Q-R-R-L-P-K-R-G-F-T-P-L-G-Q-H-L-Y-A-E-V-R-P-S-E-L-Q-L-M-E-A-E-E-I-D-V-Q-A-L-K-A-A-G-V-V-G-Q-S-V-R-Y-A-K-V-I-K-S-G-E-L-S-R-K-V-V-L-R-G-I-T-A-T-A-G-A-R-A-A-I-E-A-A-G-G-S-L-A"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-T-K-V-Q-G-K-H-A-A-E-K-E-N-D-D-G-L-R-E-K-M-I-A-V-N-R-V-S-K-V-V-K-G-G-R-T-M-S-F-A-A-L-S-V-V-G-D-G-D-G-R-I-G-M-G-K-G-K-A-R-E-V-P-V-S-V-Q-K-A-M-E-Q-A-R-R-G-M-F-K-V-A-L-K-N-G-T-L-H-H-T-V-V-G-K-H-G-A-S-T-V-L-I-S-P-A-A-E-G-T-G-V-I-A-G-G-P-M-R-A-I-F-E-V-M-G-V-R-N-V-V-A-K-S-L-G-S-S-N-P-Y-N-L-V-R-A-T-L-N-G-L-R-A-S-L-T-P-A-E-V-A-A-K-R-G-K-S-V-E-E-I-L-G"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-V-S-R-L-R-R-A-V-P-T-R-R-K-I-A-Q-L-R-V-H-R-L-S-V-F-R-S-N-L-H-I-Y-A-N-I-I-S-P-E-G-D-R-V-L-V-S-A-S-T-L-E-A-E-V-R-A-Q-L-G-G-A-G-K-G-G-N-A-T-A-A-A-L-V-G-K-R-V-A-E-K-A-K-A-A-G-I-E-L-V-A-F-D-R-S-G-F-R-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-A-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-A-K-Y-P-V-E-L-P-K-G-V-E-A-S-I-Q-P-D-Q-I-T-V-K-G-P-L-G-T-L-V-Q-S-L-T-G-D-V-N-V-A-Q-E-D-G-K-L-T-F-V-V-A-N-D-S-R-H-A-N-A-M-S-G-T-L-R-A-L-V-A-N-M-V-T-G-V-S-K-G-F-E-R-K-L-N-L-V-G-V-G-Y-R-A-Q-I-Q-G-D-A-V-K-L-Q-L-G-F-S-H-D-V-V-H-Q-L-P-A-G-V-K-A-E-C-P-T-Q-T-E-I-V-I-K-G-P-N-K-Q-V-V-G-Q-V-A-A-E-I-R-K-Y-R-E-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-R-V-V-I-K-E-T-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-S-D-P-I-A-D-M-L-T-R-I-R-N-A-Q-Q-V-D-K-T-T-V-T-M-P-A-S-K-L-K-V-A-I-A-T-V-L-K-D-E-G-Y-I-D-G-Y-S-V-K-G-T-Q-A-K-P-E-L-E-I-T-L-K-Y-Y-A-G-R-P-V-I-E-R-I-E-R-V-S-R-P-G-L-R-I-Y-K-G-R-T-S-I-P-Q-V-M-N-G-L-G-V-A-I-V-S-T-S-R-G-V-M-T-D-R-K-A-R-A-N-G-V-G-G-E-V-L-C-Y-V-A"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-L-S-L-I-N-R-D-I-K-R-A-K-L-A-D-K-Y-A-A-K-R-A-E-L-K-A-I-I-D-D-Q-S-K-T-D-E-E-R-Y-Q-A-R-L-K-L-Q-Q-L-P-R-N-A-N-P-T-R-Q-R-N-R-C-V-V-T-G-R-P-R-G-V-F-R-K-F-G-L-T-R-H-K-L-R-E-M-A-M-K-G-E-V-P-G-M-T-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-R-L-Q-E-F-Y-K-S-K-V-V-A-D-L-Q-A-K-F-G-Y-K-C-V-M-E-V-P-R-I-T-K-I-T-L-N-M-G-V-S-E-A-V-A-D-K-K-V-I-E-H-A-V-S-D-L-T-K-I-S-G-Q-K-P-V-V-T-K-T-R-K-A-I-A-G-F-K-I-R-E-N-Y-P-I-G-C-M-V-T-L-R-G-Q-R-M-Y-E-F-L-D-R-L-V-A-V-A-L-P-R-V-R-D-F-R-G-I-S-G-R-A-F-D-G-R-G-N-Y-N-I-G-V-K-E-Q-I-I-F-P-E-I-E-Y-D-K-I-D-A-L-R-G-L-N-I-S-I-T-T-T-A-K-T-D-D-E-A-K-A-L-L-T-A-F-S-F-P-F-R-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-N-N-I-R-K-G-D-E-V-I-V-L-T-G-R-D-K-K-R-R-G-T-V-L-A-R-V-D-A-D-H-V-L-V-E-G-V-N-V-V-K-K-H-V-K-A-N-P-M-A-N-N-P-G-G-I-V-E-K-T-M-P-I-H-V-S-N-V-A-L-F-N-P-A-T-G-K-G-D-R-V-G-V-Q-E-V-D-G-R-K-V-R-V-F-R-S-N-G-A-V-V-G-A-K-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-T-L-D-V-A-D-N-T-G-A-R-A-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-G-I-G-D-I-I-K-V-S-V-K-D-A-A-P-R-G-R-V-K-K-G-E-I-Y-N-A-V-V-V-R-T-A-K-G-V-R-R-K-D-G-S-L-I-R-F-G-G-N-A-A-V-L-L-N-A-K-L-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-R-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-T-Q-N-T-Q-V-A-K-R-Q-R-T-L-V-G-K-V-V-S-N-K-M-D-K-T-V-V-V-L-V-E-R-R-V-K-H-P-I-F-G-K-I-I-M-R-S-A-K-Y-K-A-H-D-E-S-N-Q-Y-N-E-G-D-T-V-E-I-A-E-G-R-P-I-S-R-S-K-A-W-R-V-V-R-L-V-E-A-A-R-V-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-S-R-R-K-Y-R-K-E-Q-K-G-R-N-T-G-L-A-S-R-G-T-H-V-S-F-G-E-F-G-L-K-A-T-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-I-N-R-H-I-K-R-G-G-R-I-W-I-R-I-F-P-D-K-P-I-S-Q-K-P-A-E-V-R-M-G-N-G-K-G-N-P-E-Y-W-V-A-E-I-Q-P-G-K-V-L-Y-E-M-E-G-V-S-E-E-L-A-R-E-A-F-R-L-A-A-A-K-L-P-I-S-T-T-F-V-A-R-H-I-G-A"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-T-A-I-I-R-G-V-H-I-S-A-Q-K-T-R-L-V-A-D-L-I-R-G-K-S-V-A-Q-A-L-N-I-L-T-F-S-P-K-K-A-A-V-I-L-K-K-A-V-E-S-A-I-A-N-A-E-H-N-D-G-A-D-I-D-E-L-K-V-T-T-I-F-V-D-K-A-Q-S-M-K-R-F-S-A-R-A-K-G-R-G-N-R-I-E-K-Q-T-C-H-I-T-V-K-V-G-A"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-I-K-K-G-P-F-V-D-A-H-L-I-K-K-V-D-A-A-V-A-G-K-D-K-K-P-I-K-T-W-S-R-R-S-T-V-L-P-E-F-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-Y-I-N-E-N-M-V-G-H-K-L-G-E-F-A-L-T-R-T-F-K-G-H-A-A-D-K-K-S-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-A-E-R-L-M-Q-V-I-L-A-P-I-V-T-E-K-A-T-F-V-A-E-K-N-Q-Q-V-A-F-R-V-V-A-D-A-T-K-P-E-I-K-A-A-V-E-L-L-F-K-V-Q-V-E-S-V-Q-V-L-N-R-K-G-K-V-K-R-F-G-R-F-V-G-R-R-R-N-E-R-K-A-Y-V-A-L-K-D-G-Q-E-I-D-F-A-E-V-K"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-N-Q-K-I-R-I-R-L-K-A-F-D-Y-K-L-I-D-Q-S-A-A-E-I-V-D-T-A-K-R-T-G-A-V-V-R-G-P-V-P-L-P-T-R-I-R-R-Y-D-V-L-R-S-P-H-V-N-K-T-S-R-D-Q-F-E-I-H-T-H-Q-R-L-M-D-I-V-D-P-T-D-K-T-V-D-A-L-M-R-L-D-L-P-A-G-V-D-V-E-I-A-L-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-E-V-P-K-R-E-I-L-P-D-P-K-F-G-S-V-E-L-A-K-F-M-N-V-V-M-L-D-G-K-K-A-V-A-E-R-I-I-Y-G-A-L-E-Q-V-Q-V-K-T-G-K-D-A-I-E-V-F-N-L-A-I-N-N-I-K-P-I-V-E-V-K-S-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-R-P-V-R-R-L-A-L-A-M-R-W-L-R-E-A-A-K-K-R-G-E-K-S-M-D-L-R-L-A-G-E-L-I-D-A-S-E-G-R-G-A-A-M-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-S-H-F-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-S-Q-L-V-R-K-P-R-E-V-S-I-I-K-S-K-S-P-A-L-E-N-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-V-R-L-T-N-G-Y-E-V-I-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-S-L-D-L-Q-G-V-K-D-R-K-Q-A-R-S-K-Y-G-A-K-R-P-K-K-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-S-K-A-E-I-L-D-A-I-A-G-M-S-V-L-E-L-S-E-L-I-K-E-M-E-E-K-F-G-V-S-A-A-A-A-A-V-A-V-A-A-P-A-A-G-G-A-G-A-A-A-A-E-E-Q-T-E-F-T-V-V-L-L-E-A-G-A-N-K-V-S-V-I-K-A-V-R-E-L-T-G-L-G-L-K-E-A-K-D-L-V-D-G-A-P-K-P-V-K-E-A-L-P-K-A-D-A-E-A-A-K-K-K-L-E-E-A-G-A-K-V-E-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-L-N-R-Q-E-K-A-V-V-I-E-E-V-S-A-Q-V-A-K-A-Q-S-I-V-I-A-E-Y-R-G-L-D-V-A-S-V-T-V-L-R-K-T-A-R-E-S-G-V-Y-L-R-V-L-K-N-T-L-V-R-R-A-V-A-G-T-A-F-E-P-L-S-E-Q-L-T-G-P-L-I-Y-G-I-S-A-D-P-V-A-A-A-K-V-L-A-G-F-A-K-S-N-D-K-L-V-I-K-A-G-S-L-P-N-S-L-L-T-Q-D-G-V-K-A-L-A-T-M-P-S-R-E-E-L-L-S-K-L-L-G-T-M-Q-A-P-I-A-Q-F-V-R-T-L-N-E-V-P-T-K-F-A-R-G-L-A-A-V-R-D-Q-K-A-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-V-G-F-I-K-L-Q-V-P-A-G-K-A-N-P-S-P-P-I-G-P-A-L-G-Q-R-G-L-N-I-M-E-F-C-K-A-F-N-A-K-T-Q-G-M-E-P-G-L-P-I-P-V-V-I-T-A-F-A-D-K-S-F-T-F-I-M-K-T-P-P-A-T-V-L-I-K-K-A-S-G-V-Q-K-G-S-A-K-P-H-T-D-K-V-G-T-L-T-R-A-Q-A-E-E-I-A-K-T-K-Q-P-D-L-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-I-T-V-E-G-V"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-P-R-A-T-L-P-A-E-A-R-L-H-R-P-S-E-F-A-A-A-L-K-G-R-R-L-A-R-G-A-F-F-I-V-S-A-S-P-C-A-P-A-D-D-Q-P-A-R-A-R-L-G-L-V-I-A-K-R-F-A-A-R-A-V-T-R-N-T-L-K-R-V-I-R-E-A-F-R-A-R-R-L-A-L-P-A-Q-D-Y-V-V-R-L-H-S-K-L-T-P-A-S-L-T-A-L-K-R-S-A-R-A-E-V-D-A-H-F-T-R-I-A-R"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-K-A-T-G-F-I-K-E-F-R-D-F-A-V-K-G-N-A-I-D-L-A-V-G-V-I-I-G-A-A-F-G-K-I-V-D-S-L-V-K-D-V-V-M-P-L-V-N-F-I-L-G-G-S-V-D-F-S-N-K-F-L-V-L-S-M-P-D-G-Y-T-G-P-M-M-Y-A-D-L-T-K-A-G-A-N-V-L-A-W-G-N-F-I-T-I-I-I-N-F-V-L-L-A-F-V-I-F-W-M-V-K-A-I-Y-S-A-R-R-K-E-E-A-A-P-E-A-P-A-A-P-P-E-D-V-T-V-L-R-E-I-R-D-L-L-K-D-K-Q-G-S"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-V-S-F-T-E-L-M-V-I-G-V-I-A-L-V-V-I-G-P-E-R-L-P-K-V-A-R-T-I-G-H-L-L-G-R-A-Q-R-Y-V-N-D-V-K-S-D-I-R-R-E-I-E-L-D-E-L-R-K-F-K-D-E-M-D-E-T-A-R-S-M-Q-T-S-L-R-E-T-E-D-T-L-R-D-S-T-Q-A-L-R-A-E-L-D-D-T-A-R-D-A-S-K-A-V-N-G-A-D-A-P-A-E-P-A-P-A-V-A-S-D-T-D-T-D-T-D-T-R-S-I-A-P-P-A-A-A-T-P-A-D-K-T-P-P-T-G-S-A-T"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-I-W-H-W-L-I-V-L-V-I-I-A-L-V-F-G-T-K-K-L-R-N-V-G-S-D-L-G-S-A-V-K-G-F-K-E-G-M-K-D-A-S-A-D-K-P-A-D-Q-V-T-Q-Q-R-V-S-D-D-T-I-D-V-Q-A-K-E-K-S-N-S"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-L-N-A-T-I-F-F-Q-M-L-V-F-F-V-L-G-W-F-T-M-K-F-V-W-P-P-L-T-K-A-I-D-E-R-R-Q-K-I-A-D-G-L-A-A-A-E-K-G-K-A-D-L-A-Q-A-Q-A-R-V-S-L-I-E-A-S-A-K-S-E-T-H-A-R-I-I-E-A-E-K-Q-A-A-S-V-I-E-Q-A-R-R-E-A-E-A-E-R-A-R-I-V-A-Q-A-A-Q-D-A-A-Q-E-V-Q-R-A-R-E-A-L-R-D-D-V-A-A-L-A-V-K-G-A-E-Q-I-L-K-R-E-V-D-A-R-A-H-A-E-L-L-N-Q-L-K-A-Q-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-L-S-T-V-A-R-P-Y-A-E-A-L-F-G-A-A-R-D-D-K-A-G-L-A-V-W-A-D-L-V-S-E-M-A-Q-V-A-A-N-P-D-V-R-E-A-M-A-D-P-R-L-D-D-K-Q-R-S-E-V-F-T-G-L-I-K-S-Q-L-P-Q-A-A-R-N-F-I-E-L-L-V-K-N-D-R-L-L-L-L-P-V-I-A-T-Q-F-V-A-L-K-N-R-H-E-G-T-A-Q-A-E-I-T-S-A-F-E-L-S-D-A-Q-V-K-E-L-I-A-A-L-E-L-K-F-G-L-K-L-K-P-H-V-S-V-D-Q-E-L-I-G-G-V-R-V-A-V-G-D-Q-V-L-D-T-S-V-K-A-Q-L-A-R-L-R-D-T-L-A-A"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-T-L-H-V-D-V-V-S-A-E-E-A-I-F-T-G-E-A-K-F-V-V-L-P-G-E-A-G-E-L-G-I-L-P-G-H-T-P-L-I-S-R-I-R-P-G-T-V-K-I-V-R-A-D-E-G-E-E-N-I-F-V-A-G-G-I-L-E-V-Q-P-G-S-V-T-V-L-A-D-T-A-I-R-A-A-D-L-D-E-A-R-A-V-A-A-R-E-K-A-E-E-A-L-R-N-A-K-D-K-A-D-I-A-V-V-E-A-E-L-A-M-L-A-A-Q-A-V-A-A-R-K-L-R-Q-G-R-T-H"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-L-L-F-P-G-T-F-T-M-Q-T-D-Y-A-E-L-V-R-R-T-I-R-S-V-P-D-W-P-T-P-G-V-T-F-R-D-I-T-P-V-L-Q-D-P-R-T-F-R-V-L-I-D-L-F-V-Y-R-Y-M-R-Q-R-L-D-L-V-A-G-V-D-A-R-G-F-I-V-G-A-V-L-A-H-E-L-N-L-G-F-V-P-V-R-K-K-G-K-L-P-Y-R-T-V-A-E-E-Y-S-L-E-Y-G-N-A-A-V-E-M-H-T-D-S-V-R-T-G-Q-R-V-L-L-V-D-D-L-I-A-T-G-G-T-M-L-A-A-I-K-L-L-Q-R-L-G-A-N-V-V-E-A-A-A-I-I-D-L-P-Y-L-G-G-S-A-Q-I-T-A-T-G-T-P-L-Y-T-V-C-Q-Y-Q-E-G-D"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-E-E-T-L-L-A-F-D-F-G-E-K-K-I-G-I-A-I-G-N-T-L-T-R-Q-A-R-P-L-E-I-I-F-S-E-T-R-A-A-R-F-G-R-I-G-Q-L-L-Q-E-W-Q-P-Q-R-A-V-V-G-L-P-L-T-L-D-G-Q-E-Q-P-A-S-A-R-A-R-R-F-A-N-Q-L-H-G-R-F-G-L-A-V-E-L-V-D-E-R-G-S-S-M-E-A-Q-Q-L-L-G-T-H-A-A-D-D-A-V-A-A-A-V-I-L-Q-R-Y-L-D-T-L-P-Q-P"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-V-A-K-P-H-E-V-K-R-D-W-F-V-I-D-A-K-G-K-V-L-G-R-V-A-S-E-V-A-H-R-L-R-G-K-H-K-P-E-F-T-P-H-V-D-T-G-D-Y-I-V-I-I-N-A-A-D-I-V-V-T-G-N-K-A-Q-D-K-K-Y-F-R-H-T-T-Y-P-G-G-I-R-E-T-N-F-E-K-M-Q-Q-R-F-P-G-R-A-I-Q-K-A-V-K-G-M-L-P-K-G-P-L-G-Y-A-M-I-K-K-L-K-V-Y-A-G-A-E-H-P-H-T-A-Q-Q-P-K-P-L-E-F"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters ### SEQUENCE -M-N-A-V-T-E-T-V-D-L-Q-A-P-P-P-V-P-L-V-F-T-D-S-A-A-A-K-V-K-D-L-L-A-E-E-G-N-P-E-L-K-L-R-V-F-V-Q-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-V-V-N-D-D-D-T-V-L-D-K-A-G-V-Q-L-L-V-D-P-M-S-F-Q-Y-L-V-G-A-E-I-D-Y-K-E-D-L-E-G-A-Q-F-V-I-R-N-P-N-A-S-T-T-C-G-C-G-S-S-F-S-V"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-F-C-G-N-A-D-T-Q-V-V-D-S-R-V-S-E-E-G-D-T-I-R-R-R-R-R-C-L-S-C-D-K-R-F-T-T-Y-E-R-V-E-L-A-M-P-S-V-V-K-R-D-G-S-R-T-E-Y-D-A-G-K-V-R-G-S-L-S-L-A-L-R-K-R-P-V-S-T-D-E-V-D-S-A-V-A-R-I-E-E-T-L-L-A-S-G-M-R-E-V-P-S-E-Q-I-G-E-L-V-M-G-E-L-K-R-L-D-K-V-A-Y-V-R-Y-A-S-V-Y-K-S-F-E-D-I-G-E-F-V-E-A-I-R-E-M-Q-G-P-L-L-P-G-K-K-L-R-K-D"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-L-D-R-E-G-Y-R-P-N-V-G-I-I-L-V-N-G-K-N-E-V-F-W-G-K-R-I-R-E-H-A-W-Q-F-P-Q-G-G-I-K-Y-G-E-S-P-V-Q-A-M-Y-R-E-L-H-E-E-V-G-L-K-P-E-H-V-R-I-L-G-R-T-R-D-W-L-R-Y-N-V-P-D-H-F-V-R-R-E-W-R-G-H-Y-K-G-Q-K-Q-I-W-F-L-L-R-L-V-G-R-D-S-D-V-C-L-R-A-T-Q-H-P-E-F-D-A-W-R-W-S-Q-Y-W-V-P-L-D-A-V-I-E-F-K-R-D-V-Y-T-Q-A-L-N-E-L-A-V-I-L-F-R-R-H-H-E-T-R-Y-L-R-Q-R-V-H-G-P-R-S-T-D-N-P-S-S-E-T-D-G-H-A-H-I-A-G"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-H-A-I-L-K-M-G-D-P-R-L-L-R-V-A-A-P-V-E-R-Y-D-T-P-E-L-R-A-L-I-D-D-M-F-E-T-M-A-H-A-Q-G-V-G-L-A-A-P-Q-I-G-V-D-L-Q-L-V-I-F-G-F-E-R-N-D-R-Y-P-D-A-P-A-V-P-R-T-I-L-C-N-P-V-I-E-P-L-S-D-E-M-E-D-G-W-E-G-C-L-S-V-P-G-L-R-G-L-V-P-R-Y-R-H-I-R-Y-S-G-Y-D-P-A-G-Q-R-I-E-R-E-A-E-G-F-H-A-R-V-V-Q-H-E-C-D-H-L-I-G-R-L-Y-P-T-R-I-R-D-L-T-K-F-G-Y-T-E-V-L-F-P-E-M-D-P-N-A-D"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-F-L-S-F-L-L-G-Q-K-K-S-S-A-S-V-A-K-E-R-L-Q-I-I-L-A-H-E-R-G-R-G-D-S-P-D-Y-L-P-Q-L-Q-Q-E-L-V-A-V-I-S-K-Y-V-K-I-D-P-E-D-I-K-V-H-L-E-R-Q-D-T-L-E-V-L-E-V-K-I-E-M-P-Q-N"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-I-T-G-T-L-I-E-K-S-P-P-V-V-C-V-D-V-N-G-V-G-Y-E-I-D-V-P-M-S-T-L-Y-A-L-P-E-T-G-A-R-V-T-L-F-T-H-L-V-V-R-E-D-A-Q-L-L-Y-G-F-G-S-S-A-E-R-S-T-F-R-E-L-I-K-V-T-G-I-G-A-R-T-A-L-A-V-L-S-G-L-S-V-A-E-L-S-Q-A-I-T-L-Q-E-T-G-R-L-T-R-V-P-G-I-G-K-K-T-A-E-R-L-L-L-E-M-R-G-K-L-G-A-D-I-G-A-T-P-H-A-A-G-G-H-Q-S-D-I-L-N-A-L-L-A-L-G-Y-S-D-K-E-S-Q-A-A-L-K-K-L-P-E-G-V-D-V-S-E-G-I-R-L-A-L-K-A-L-V-R"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-A-P-Q-E-P-V-D-S-T-P-E-S-G-E-N-A-A-T-P-G-L-E-D-D-L-S-A-E-L-A-A-L-R-A-E-L-E-A-A-Q-A-T-V-K-A-Q-Q-E-Q-V-L-R-A-A-A-E-A-E-N-V-R-R-R-A-Q-E-D-V-A-K-A-R-K-F-G-I-E-S-F-A-E-S-L-V-P-V-K-D-S-L-E-A-A-L-A-Q-P-D-Q-A-A-Q-A-W-R-E-G-V-E-V-T-L-K-Q-L-T-A-A-F-E-R-N-L-L-K-E-I-A-P-A-Q-G-D-K-F-D-P-H-L-H-Q-A-I-S-S-V-P-A-D-Q-P-A-N-T-V-L-Q-L-L-Q-K-G-Y-V-I-A-D-R-T-L-R-P-A-L-V-V-V-S-A-G-Q-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-V-A-D-I-K-K-S-E-I-V-A-Q-F-Q-R-A-Q-G-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-R-I-N-E-L-T-G-H-F-K-E-H-M-K-D-H-H-S-R-R-G-L-L-R-M-V-S-R-R-R-K-L-L-D-Y-L-K-G-R-N-P-D-S-Y-R-A-L-I-E-K-L-G-L-R-K"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-P-A-I-P-P-K-L-I-L-A-S-S-S-R-Y-R-R-E-L-L-S-R-L-R-L-P-F-T-A-I-S-P-D-V-D-E-T-P-Q-P-G-E-A-P-A-D-L-A-L-R-L-S-V-A-K-A-M-A-V-A-A-T-H-P-G-S-V-V-I-G-S-D-Q-V-A-T-V-D-G-D-P-I-G-K-P-G-G-F-E-R-A-R-E-Q-L-R-R-L-S-G-R-A-V-E-F-H-S-A-M-A-V-T-D-G-V-H-T-E-T-A-D-I-V-T-L-C-R-F-R-T-L-T-D-A-A-I-D-A-Y-L-R-A-E-E-P-Y-D-T-A-G-S-A-K-A-E-S-L-G-I-A-L-M-D-S-I-R-S-D-D-P-T-A-I-I-G-L-P-L-I-A-L-T-R-M-L-G-R-F-G-L-D-P-L-T-G-H-P-A"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-E-S-I-E-Q-R-V-K-K-I-V-A-E-Q-L-G-V-N-E-A-E-I-K-N-E-S-S-F-L-D-D-L-G-A-D-S-L-D-M-V-E-L-V-M-A-L-E-D-E-F-E-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-Q-A-V-D-Y-I-N-S-H-G-K-Q"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-L-L-F-L-V-L-L-V-L-L-G-L-I-Q-Y-P-L-W-L-G-K-G-G-W-F-K-V-W-D-L-Q-R-Q-V-A-E-Q-R-E-T-N-D-G-L-R-A-R-N-T-A-L-E-A-E-V-R-D-L-A-T-G-V-G-A-V-E-E-R-A-R-S-E-L-G-M-M-R-E-G-E-V-F-V-H-I-L-P-P-G-T-P-L-P-S-G-N-S-T-P-Q-A-S-A-L-S-K-P-R-P-P-A-T-P-P-R-R"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-A-A-L-A-A-R-Y-P-Q-L-A-A-R-D-T-D-Y-A-V-K-T-M-L-D-A-M-T-Q-A-L-A-S-G-Q-R-I-E-I-R-G-F-G-S-F-S-L-S-Q-R-S-P-R-I-G-R-N-P-K-S-G-E-Q-V-L-V-P-G-K-Q-V-P-H-F-K-A-G-K-E-L-R-E-R-V-D-L-V-G-N-D-Q-G-D-D-S-S-N-G-S-S-D-P-L-Q-S-V-M-D-M-H-A-M-H"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-V-E-D-C-L-N-Q-I-P-N-R-F-K-L-T-L-A-A-T-Y-R-A-R-E-L-A-Q-G-H-A-P-R-L-D-S-K-D-K-P-T-V-T-A-L-R-E-I-A-S-G-L-T-G-L-E-M-L-R-K-V-P-T"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-S-N-K-G-Q-T-L-Q-D-P-F-L-N-T-L-R-K-E-H-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-Y-V-V-L-L-R-N-T-V-T-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-A-V-N-F-Q-V-E-V-P-A-E"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-G-T-T-M-L-A-E-P-R-T-L-T-K-A-E-L-A-E-L-L-F-E-R-V-G-L-N-K-R-E-A-K-D-I-V-D-T-F-F-E-E-I-R-D-A-L-A-R-G-D-S-V-K-L-S-G-F-G-N-F-Q-V-R-D-K-P-P-R-P-G-R-N-P-K-T-G-E-T-I-P-I-A-A-R-R-V-V-T-F-H-A-S-Q-K-L-K-S-V-V-E-Q-P-S-S-P-P-D-P-A-S-A-E"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-R-A-R-H-K-K-V-I-A-A-A-K-G-Y-R-G-R-R-G-N-V-F-R-I-A-K-Q-A-V-M-R-A-G-Q-Y-A-Y-R-D-R-R-N-K-K-R-T-F-R-A-L-W-I-T-R-I-N-A-A-V-R-E-Q-G-M-S-Y-S-V-F-I-A-G-L-K-K-A-A-I-E-L-D-R-K-V-L-A-D-L-A-V-R-D-K-A-G-F-A-A-I-V-Q-Q-A-K-A-A-L-A-A"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-S-T-L-D-T-Q-H-D-V-V-V-E-K-Q-P-A-R-T-A-P-P-P-M-Y-Q-V-V-L-L-N-D-D-Y-T-P-M-E-F-V-V-K-V-L-Q-K-F-F-G-K-N-S-E-D-A-T-R-I-M-L-Q-V-H-H-E-G-R-A-V-C-G-V-Y-P-R-D-L-A-A-T-R-I-A-Q-V-S-Q-Y-A-R-A-R-Q-H-P-L-Q-C-I-M-E-P-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-A-Q-A-R-K-R-A-R-Q-S-V-Q-R-N-K-H-N-S-S-L-R-S-M-L-R-T-A-I-K-R-V-R-Q-S-I-A-T-G-D-K-A-A-A-G-E-T-L-R-K-A-T-S-V-I-D-S-V-A-D-K-N-I-I-H-K-N-K-A-A-R-H-K-S-R-L-A-A-A-V-K-A-L-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-E-K-V-A-N-L-G-N-L-G-E-V-V-R-V-R-D-G-Y-A-R-N-F-L-I-P-Q-K-K-A-R-R-A-T-D-A-A-L-K-E-F-E-A-R-R-A-E-L-E-K-V-Q-A-E-K-L-A-A-A-Q-A-L-A-E-R-L-N-G-F-Q-L-K-I-S-Q-K-A-G-V-D-G-R-L-F-G-S-V-T-N-A-D-V-A-E-G-L-R-K-A-G-F-E-A-V-E-K-S-Q-V-R-M-P-N-G-Q-I-K-A-V-G-E-Y-P-V-Q-A-V-L-H-A-D-V-V-A-D-V-V-V-L-V-E-G-E-M-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-F-F-G-K-R-K-E-K-R-K-F-T-Q-Q-N-P-L-F-K-R-R-K-F-C-R-F-T-A-A-G-V-E-E-I-D-Y-K-D-L-D-T-L-R-D-F-V-Q-E-N-G-K-I-I-P-A-R-L-T-G-T-R-A-I-Y-Q-R-Q-L-D-T-A-I-K-R-A-R-F-L-A-L-L-P-Y-T-D-N-H-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-V-V-F-I-V-H-P-D-Q-S-E-Q-V-P-A-M-V-E-R-Y-Q-A-L-V-T-G-Q-S-G-T-V-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-Q-K-L-V-K-A-H-Y-V-C-M-N-I-E-C-G-Q-A-T-L-D-E-L-E-H-S-F-R-Y-N-D-A-V-L-R-H-L-V-I-K-T-K-K-A-P-A-A-P-S-I-M-M-K-S-V-E-R-E-E-A-R-K-A-S-A-E-A-A-A-T-A-T-A-A-E"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-S-S-K-Q-A-D-P-Q-T-D-A-R-P-L-P-Q-D-F-E-T-A-L-A-E-L-E-S-L-V-S-A-M-E-N-G-T-L-P-L-E-Q-S-L-S-A-Y-R-R-G-V-E-L-A-R-V-C-Q-D-R-L-A-Q-A-E-Q-Q-V-K-V-L-E-G-D-L-L-R-P-L-D-P-A-A-L-D-D-E"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-G-V-T-R-I-G-L-L-G-G-S-F-D-P-V-H-V-A-H-I-A-L-A-D-T-A-R-Q-F-L-G-L-D-Q-V-Q-L-I-P-A-A-N-P-W-Q-R-Q-P-L-K-A-S-A-P-H-R-L-R-M-L-E-L-A-I-A-G-H-P-A-L-A-I-N-P-V-E-I-E-R-G-G-A-T-Y-T-A-D-T-V-R-A-L-P-G-G-P-Q-Y-F-W-L-L-G-T-D-Q-L-Q-N-F-C-T-W-R-D-W-Q-D-I-A-A-R-I-E-L-A-V-A-T-R-P-G-A-S-I-A-P-P-A-E-L-A-T-W-L-A-A-H-R-R-Q-L-H-E-L-P-F-A-P-M-A-V-S-A-S-D-I-R-Q-R-L-A-A-D-A-A-T-D-G-L-L-P-E-P-V-A-A-Y-I-A-T-H-H-L-Y-R"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-L-I-V-A-A-V-G-T-R-M-P-G-W-V-E-T-A-W-D-D-Y-A-K-R-L-P-A-D-C-A-L-E-L-R-E-I-K-P-E-P-R-T-S-G-K-T-P-A-Q-M-M-A-A-E-A-R-R-I-E-T-A-Q-P-P-G-V-L-R-I-A-L-D-E-R-G-R-D-L-T-T-V-A-L-S-Q-Q-L-E-K-W-R-A-G-G-R-D-V-A-F-L-V-G-G-P-D-G-L-D-A-A-L-K-A-S-C-E-G-L-L-R-L-S-S-L-T-L-P-H-P-M-V-R-V-L-L-A-E-Q-L-Y-R-A-W-A-I-M-T-N-H-P-Y-H-R-A"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-T-A-Q-E-L-R-V-G-N-V-I-M-V-G-K-D-P-L-V-V-Q-K-T-E-Y-N-K-S-G-R-N-A-A-V-V-K-L-K-F-K-N-L-L-T-G-S-G-S-E-S-V-Y-K-A-D-E-K-F-D-V-V-V-L-E-R-K-E-C-T-Y-S-Y-F-G-D-P-M-Y-V-F-M-D-E-E-Y-N-Q-Y-E-I-E-A-D-S-M-G-D-A-L-N-Y-L-E-E-A-M-P-V-E-V-V-F-Y-D-G-R-A-I-S-V-E-L-P-T-I-L-V-R-E-I-T-Y-T-E-P-A-V-R-G-D-T-S-G-K-V-L-K-P-A-K-I-N-T-G-F-E-L-S-V-P-L-F-C-A-I-G-D-K-I-E-I-D-T-R-T-N-E-Y-R-S-R-V-N"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-A-A-D-D-H-F-S-L-F-G-L-P-A-R-F-A-L-D-P-V-Q-L-E-Q-A-W-R-A-V-A-A-R-V-H-P-D-R-Y-A-T-A-S-A-A-E-R-R-V-A-M-Q-W-A-A-R-A-N-E-A-Y-R-Q-L-R-D-P-M-L-R-A-R-Y-L-C-E-Q-A-G-V-D-L-Q-T-E-S-N-T-A-M-D-P-A-F-L-M-Q-Q-M-E-W-R-E-M-L-D-D-A-R-R-D-P-A-A-F-A-A-L-R-A-E-L-E-Q-A-R-L-R-M-Q-Q-T-L-S-E-L-I-D-E-R-G-D-Y-Q-Q-A-G-T-K-V-R-E-W-M-F-V-E-K-L-A-Q-E-L-S-A-A-Q-P-M-Q"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-S-V-D-L-K-I-L-D-A-R-M-R-E-Y-L-P-A-Y-A-T-P-G-S-A-G-L-D-L-R-A-C-T-E-A-S-L-V-I-E-P-G-Q-T-V-L-V-P-T-G-L-A-I-H-I-G-D-P-R-Y-A-A-M-I-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-Q-L-M-V-S-T-W-N-R-G-T-Q-P-F-T-L-D-P-M-E-R-L-A-Q-L-V-I-V-P-V-Q-Q-V-A-F-N-V-V-E-D-F-D-A-S-E-R-G-A-G-G-F-G-S-T-G-R-A"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-R-L-I-G-L-D-G-E-Q-L-G-I-V-K-I-A-D-A-F-R-L-S-E-Q-S-D-V-D-L-V-E-I-A-P-N-A-D-P-P-V-C-R-L-M-D-Y-G-K-F-K-Y-Q-E-Q-K-R-Q-A-E-A-R-S-K-Q-K-V-I-Q-V-K-E-V-K-F-R-P-A-T-D-E-G-D-Y-Q-V-K-L-R-N-L-R-R-F-L-E-E-G-D-K-A-K-V-T-L-R-F-R-G-R-E-M-A-H-Q-E-L-G-M-R-V-L-E-R-V-R-D-D-L-I-E-L-A-Q-V-E-A-M-P-K-L-E-G-R-Q-M-V-M-V-L-A-P-R-K-K-A-V-G-K-P-D-A-A-G"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-R-N-V-K-D-V-M-G-T-E-D-E-V-R-T-D-T-W-V-S-R-R-V-L-L-K-K-D-G-M-G-F-S-F-H-E-T-T-I-F-P-G-T-R-T-H-I-H-Y-K-N-H-L-E-A-V-W-C-I-E-G-D-G-S-I-E-T-I-A-D-G-K-T-Y-E-L-G-P-G-V-V-Y-A-L-N-E-N-D-E-H-W-L-C-G-G-K-Q-P-L-R-V-I-C-V-F-N-P-P-L-T-G-Q-E-V-H-D-A-E-G-V-Y-A-L-V-E-E-A-A"} +{"text": "### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate with acetyl coenzyme A ### SEQUENCE -M-R-K-D-E-T-S-N-T-S-P-D-I-S-V-A-Q-P-A-S-A-L-R-Y-H-L-R-P-P-R-R-N-D-G-A-A-I-H-Q-L-V-S-E-C-P-P-L-D-L-N-S-L-Y-A-Y-L-L-L-C-E-H-H-A-H-T-C-V-V-A-E-S-P-G-G-R-I-D-G-F-V-S-A-Y-L-L-P-T-R-P-D-V-L-F-V-W-Q-V-A-V-H-S-R-A-R-G-H-R-L-G-R-A-M-L-G-H-I-L-E-R-Q-E-C-R-H-V-R-H-L-E-T-T-V-G-P-D-N-Q-A-S-R-R-T-F-A-G-L-A-G-E-R-G-A-H-V-S-E-Q-P-F-F-D-R-Q-A-F-G-G-A-D-H-D-D-E-M-L-L-R-I-G-P-F-T-H-P-P-H"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-R-R-H-K-S-K-S-I-P-G-R-N-L-R-L-A-D-Q-I-Q-K-D-L-A-G-I-I-Q-R-E-I-D-M-T-R-A-G-L-I-T-L-S-G-V-E-L-S-A-D-Y-A-H-A-K-V-Y-F-T-V-L-G-A-E-P-D-T-A-A-A-L-L-N-E-K-A-G-W-L-H-S-Q-L-Y-K-L-L-H-I-H-T-V-P-T-L-R-F-V-H-D-L-Q-I-T-R-G-I-E-M-S-V-L-I-D-R-A-N-R-P-G-P-H-S-G-V-P-D-E-P-E-D-Q-S"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-D-L-F-A-L-T-E-E-A-L-A-G-M-D-I-E-L-V-D-V-E-R-A-A-M-G-L-L-R-V-T-I-D-R-V-D-G-V-R-I-E-D-C-E-Q-V-S-R-Q-L-S-H-V-Y-E-V-E-N-I-D-Y-K-R-L-E-V-G-S-P-G-V-D-R-P-L-R-N-E-A-E-F-R-R-F-A-G-E-R-I-E-I-K-L-R-E-A-L-D-G-R-K-V-F-S-G-T-L-R-A-P-E-A-D-G-A-S-G-Q-D-D-T-A-G-A-G-K-A-V-F-G-L-E-F-E-A-K-K-N-D-I-Q-V-L-S-F-T-L-D-D-I-E-R-A-K-L-D-P-V-L-D-F-K-G-K-K-R"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-T-F-A-P-L-N-F-L-A-I-G-V-G-A-T-L-G-A-W-L-R-W-V-P-G-L-R-L-N-G-A-G-W-P-W-G-T-L-T-A-N-L-V-G-G-Y-L-I-G-V-M-V-A-L-I-A-S-H-P-E-W-P-A-W-I-R-L-A-A-V-T-G-F-L-G-G-L-T-T-F-S-T-F-S-A-E-T-V-D-M-L-E-R-G-V-Y-A-T-A-A-A-Y-A-G-A-S-L-A-G-S-L-A-M-T-G-L-A-T-V-R-L-L-L-R"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-S-S-V-S-A-A-G-A-T-P-P-A-S-P-G-C-I-A-G-I-G-M-D-L-L-R-I-E-R-I-E-R-A-L-A-R-H-G-D-R-F-A-Q-K-I-L-G-P-E-E-L-A-K-F-H-A-R-R-R-R-D-P-A-R-G-V-R-F-L-A-T-R-F-A-A-K-E-A-F-S-K-A-I-G-L-G-M-R-M-P-M-S-W-R-R-V-Q-T-L-N-A-L-G-G-R-P-V-L-V-I-G-A-E-L-A-D-W-F-D-A-R-F-G-A-A-H-V-S-I-T-D-E-S-D-M-A-A-A-Y-V-I-V-E-R-K-P-A-P-D-G-R-P"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-A-N-E-N-R-L-V-W-L-D-M-E-M-T-G-L-D-P-E-K-E-R-I-I-E-V-A-V-V-V-T-E-A-D-L-T-V-V-A-E-G-P-V-L-V-V-H-Q-P-D-S-L-L-D-A-M-D-N-W-N-K-S-T-H-G-K-S-G-L-I-E-K-V-K-A-S-T-L-G-E-A-Q-A-E-Q-I-L-L-E-F-L-A-E-H-V-P-A-G-K-S-P-L-C-G-N-T-I-S-Q-D-R-R-F-M-Y-A-Y-M-P-N-L-E-R-F-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-A-R-R-W-A-P-A-V-Y-K-G-F-D-K-K-S-R-H-E-A-L-A-D-I-Y-E-S-I-D-E-L-K-Y-Y-R-E-H-L-L-K-V"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-L-I-A-I-L-E-Q-E-E-I-A-R-L-T-G-G-N-A-V-T-E-F-A-P-G-D-T-V-V-V-S-V-N-V-V-E-G-T-R-K-R-V-Q-A-F-E-G-V-V-I-A-K-R-N-R-G-L-N-S-S-F-I-V-R-K-I-S-S-G-E-A-V-E-R-T-F-Q-L-Y-S-P-Q-I-A-G-I-E-V-K-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-S-R-S-G-K-S-A-R-I-K-E-K-L-V-L-K-K-A-K-S-A"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-I-I-D-N-R-K-A-T-H-D-Y-F-I-E-D-R-Y-E-A-G-M-V-L-E-G-W-E-V-K-A-I-R-D-G-R-V-H-L-K-E-S-Y-V-I-V-R-D-G-E-I-Y-L-L-G-M-H-V-S-P-L-P-T-A-S-T-H-I-R-P-D-A-T-R-T-R-K-L-L-L-K-A-E-E-I-R-K-L-I-G-K-V-E-Q-R-G-Y-T-L-V-P-L-N-L-H-Y-K-N-G-R-I-K-L-D-F-A-L-G-R-G-K-K-L-Y-D-K-R-D-T-A-R-E-K-D-W-Q-R-E-K-E-R-V-L-K-H-D-T-R-V-N-Q-R-D-S"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-V-A-D-I-R-K-S-A-E-T-R-M-A-K-S-L-E-T-L-K-A-S-L-A-K-I-R-T-G-R-A-H-T-G-I-L-D-H-V-Q-V-E-Y-Y-G-S-P-V-P-I-S-Q-V-A-N-V-N-L-V-D-A-R-T-I-S-V-Q-P-Y-E-K-S-M-A-G-P-I-E-K-A-I-R-E-S-D-L-G-L-N-P-V-S-M-G-E-T-I-R-V-P-M-P-A-L-T-E-E-R-R-R-D-L-T-K-V-V-K-S-E-G-E-D-A-K-V-A-V-R-N-L-R-R-E-A-N-E-A-L-K-K-L-V-K-D-K-E-I-S-E-D-D-E-R-R-A-Q-D-D-V-Q-K-L-T-D-R-A-V-G-D-I-D-K-M-I-V-Q-K-E-A-E-I-M-T-V"} +{"text": "### FUNCTION Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-K-T-A-D-S-S-L-L-A-D-I-R-E-V-N-L-S-Y-L-L-L-A-Q-R-M-L-R-D-D-Y-A-A-S-M-F-R-L-G-F-S-N-E-V-A-D-I-L-M-R-L-S-P-A-Q-L-V-K-L-A-S-S-S-S-L-L-C-R-F-R-F-D-D-Y-S-L-L-S-A-L-T-Q-D-V-L-G-G-A-L-Q-Q-A-H-A-T-I-L-L-A-R-Q-P-V-E-E-L-A"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-T-T-P-I-P-L-A-R-G-W-L-P-A-A-P-S-T-L-D-P-L-R-K-Y-W-L-F-R-P-G-A-L-T-A-G-L-R-Q-L-G-H-V-R-L-R-V-L-A-E-Y-P-T-G-A-P-R-D-E-A-D-G-M-R-I-A-A-Q-S-P-V-W-V-R-E-V-L-M-S-I-D-G-V-D-S-V-V-A-R-S-L-T-P-L-R-A-S-H-G-V-W-Q-G-M-R-R-L-L-T-R-P-L-A-D-M-L-Y-H-D-P-G-I-H-R-S-V-F-V-C-R-R-L-A-A-G-V-P-F-H-A-T-A-I-A-R-A-P-A-G-G-P-E-P-A-L-W-A-R-R-S-A-F-W-R-A-G-Q-P-L-L-V-A-E-C-F-L-P-A-F-W-S-L-A-R-A-P-V-A-P-R"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-K-G-Q-L-A-G-L-M-R-Q-A-Q-Q-M-Q-E-N-M-K-K-A-Q-D-A-L-A-E-I-Q-V-E-G-A-A-G-G-G-L-V-K-V-T-M-T-C-R-H-D-V-K-R-V-A-I-D-P-S-L-L-G-E-D-K-D-M-L-E-D-L-V-A-A-A-F-N-D-A-L-R-K-A-E-A-T-S-Q-E-K-M-A-S-V-T-A-G-M-P-L-P-P-G-M-K-L-P-F"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-L-I-E-L-N-G-I-V-D-E-V-L-P-D-S-R-Y-R-V-K-L-D-N-G-I-E-V-G-A-Y-A-S-G-R-M-R-K-H-R-I-R-I-L-A-G-D-R-V-T-L-E-M-S-P-Y-D-L-T-K-G-R-I-N-F-R-H-K-D-E-R-S-G-P-P-S-R-P-P-Q-H-R-R"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-T-E-L-S-L-S-V-Q-Y-G-V-A-D-A-R-L-P-R-W-R-L-R-R-W-V-Q-Y-A-L-A-G-A-A-G-D-G-H-A-G-L-A-G-A-E-L-G-L-R-L-V-G-L-A-E-G-R-R-L-N-R-E-F-R-G-R-D-Y-A-T-N-V-L-T-F-E-Y-G-T-G-P-D-G-V-A-R-G-D-I-V-V-C-V-P-V-L-A-R-E-A-R-E-Q-R-K-T-L-L-D-H-A-A-H-L-T-V-H-G-T-L-H-A-L-G-Y-D-H-I-K-A-G-E-A-R-R-M-E-A-L-E-T-V-V-L-A-R-M-G-I-A-D-P-Y-L-A-A"} +{"text": "### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-S-T-T-P-T-L-S-H-L-D-E-S-G-Q-I-R-M-V-D-V-G-H-K-T-D-T-D-R-V-A-I-A-R-G-S-V-R-M-N-A-T-A-Y-G-L-L-T-Q-P-G-Q-G-K-G-E-V-L-N-T-A-R-V-A-A-V-L-A-A-K-R-C-A-E-L-I-P-L-C-H-S-L-P-L-A-F-V-G-I-D-F-E-L-D-E-A-A-Y-S-V-H-I-R-A-T-C-R-T-Q-Y-K-T-G-V-E-M-E-A-M-T-A-C-S-V-A-A-L-T-I-Y-D-M-C-K-A-A-D-K-G-I-V-I-E-Q-I-R-L-Q-Y-K-A-G-G-K-S-G-E-W-R-N-D"} +{"text": "### FUNCTION Dephosphorylates the 5' and 2'-phosphates of deoxyribonucleotides ### SEQUENCE -M-L-I-L-L-D-Q-N-G-V-L-A-D-F-E-H-A-F-I-D-A-W-R-K-R-H-P-D-I-E-P-V-A-F-E-D-R-K-S-F-H-I-R-E-D-Y-A-P-E-L-R-G-L-A-E-A-I-Y-T-A-P-G-F-I-R-D-L-P-P-V-P-G-A-I-E-A-F-R-E-L-L-A-L-G-M-D-V-R-I-C-S-S-P-L-M-Q-F-E-N-Y-V-A-E-K-Y-L-W-V-E-R-H-L-G-R-E-A-T-Q-R-L-I-L-T-R-D-K-T-L-V-Q-G-D-L-L-I-D-D-R-P-V-I-T-G-A-A-R-P-R-W-R-H-I-I-Y-D-A-P-Y-N-R-D-Q-T-D-R-P-R-L-D-W-R-N-W-R-N-V-L-A-G-E-L-Y-R-S-D-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-V-A-D-I-K-K-S-E-I-V-A-Q-F-Q-R-A-Q-G-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-R-I-N-E-L-T-G-H-F-K-E-H-M-K-D-H-H-S-R-R-G-L-L-R-M-V-S-R-R-R-K-L-L-D-Y-L-K-G-R-N-P-D-S-Y-R-A-L-I-E-K-L-G-L-R-K"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-P-A-I-P-P-K-L-I-L-A-S-S-S-R-Y-R-R-E-L-L-S-R-L-R-L-P-F-T-A-I-S-P-D-V-D-E-T-P-Q-P-G-E-A-P-A-D-L-A-L-R-L-S-V-A-K-A-M-A-V-A-A-T-H-P-G-S-V-V-I-G-S-D-Q-V-A-T-V-D-G-D-P-I-G-K-P-G-G-F-E-R-A-R-E-Q-L-R-R-L-S-G-R-A-V-E-F-H-S-A-M-A-V-T-D-G-V-H-T-E-T-A-D-I-V-T-L-C-R-F-R-T-L-T-D-A-A-I-D-A-Y-L-R-A-E-E-P-Y-D-T-A-G-S-A-K-A-E-S-L-G-I-A-L-M-D-S-I-R-S-D-D-P-T-A-I-I-G-L-P-L-I-A-L-T-R-M-L-G-R-F-G-L-D-P-L-T-G-H-P-A"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-E-S-I-E-Q-R-V-K-K-I-V-A-E-Q-L-G-V-N-E-A-E-I-K-N-E-S-S-F-L-D-D-L-G-A-D-S-L-D-M-V-E-L-V-M-A-L-E-D-E-F-E-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-Q-A-I-D-Y-I-N-S-H-G-K-Q"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-L-L-F-L-V-L-L-V-L-L-G-L-I-Q-Y-P-L-W-L-G-K-G-G-W-F-K-V-W-D-L-Q-R-Q-V-A-E-Q-R-E-T-N-D-G-L-R-A-R-N-T-A-L-E-A-E-V-R-D-L-A-T-G-V-G-A-V-E-E-R-A-R-S-E-L-G-M-M-R-E-G-E-V-F-V-H-I-L-P-P-G-T-P-L-P-S-D-N-S-T-P-Q-A-S-A-L-S-K-P-R-P-P-A-T-P-P-R-R"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-P-R-A-T-L-P-A-E-A-R-L-H-R-P-S-E-F-A-A-A-L-K-G-R-R-L-A-R-G-A-F-F-I-V-S-A-S-P-C-A-P-A-D-D-Q-P-A-R-A-R-L-G-L-V-I-A-K-R-F-A-A-R-A-V-T-R-N-T-L-K-R-V-I-R-E-A-F-R-A-R-R-L-A-L-P-A-Q-D-Y-V-V-R-L-H-S-K-L-T-P-A-S-L-T-A-L-K-R-S-A-R-A-E-V-D-A-H-F-T-R-I-A-R"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-K-A-T-G-F-I-K-E-F-R-D-F-A-V-K-G-N-A-I-D-L-A-V-G-V-I-I-G-A-A-F-G-K-I-V-D-S-L-V-K-D-V-V-M-P-L-V-N-F-I-L-G-G-S-V-D-F-S-N-K-F-L-V-L-S-M-P-D-G-Y-T-G-P-M-T-Y-A-D-L-T-K-A-G-A-N-V-L-A-W-G-N-F-I-T-I-I-I-N-F-V-L-L-A-F-V-I-F-W-M-V-K-A-I-Y-S-A-R-R-K-E-E-A-A-P-E-A-P-A-A-P-P-E-D-V-T-V-L-R-E-I-R-D-L-L-K-D-K-Q-G-S"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-I-W-H-W-L-I-V-L-V-I-I-A-L-V-F-G-T-K-K-L-R-N-V-G-S-D-L-G-S-A-V-K-G-F-K-E-G-M-K-D-A-S-A-D-K-P-A-D-Q-V-T-Q-Q-R-V-S-D-D-T-I-D-V-Q-A-K-E-K-S-N-S"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-L-N-A-T-I-F-F-Q-M-L-V-F-F-V-L-G-W-F-T-M-K-F-V-W-P-P-L-T-K-A-I-D-E-R-R-Q-K-I-A-D-G-L-A-A-A-E-K-G-K-A-D-L-A-Q-A-Q-A-R-V-S-L-I-E-A-S-A-K-S-E-T-H-A-R-I-I-E-A-E-K-Q-A-A-S-V-I-E-Q-A-R-R-E-A-E-A-E-R-A-R-I-V-A-Q-A-A-Q-D-A-A-Q-E-V-Q-R-A-R-E-A-L-R-D-D-V-A-A-L-A-V-K-G-A-E-Q-I-L-K-R-E-V-D-A-R-A-H-A-E-L-L-N-Q-L-K-A-Q-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-L-S-T-V-A-R-P-Y-A-E-A-L-F-G-A-A-R-D-D-K-A-G-L-A-V-W-A-D-L-V-S-E-M-A-Q-V-A-A-N-P-D-V-R-E-A-M-A-D-P-R-L-D-D-K-Q-R-S-E-V-F-T-G-L-I-K-S-Q-L-P-Q-A-A-R-N-F-I-E-L-L-V-K-N-D-R-L-L-L-L-P-V-I-A-T-Q-F-V-A-L-K-N-R-H-E-G-T-A-Q-A-E-I-T-S-A-F-E-L-S-D-A-Q-V-K-E-L-I-A-A-L-E-L-K-F-G-L-K-L-K-P-H-V-S-V-D-Q-E-L-I-G-G-V-R-V-A-V-G-D-Q-V-L-D-T-S-V-K-A-Q-L-A-R-L-R-D-T-L-A-A"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-T-L-H-V-D-V-V-S-A-E-E-A-I-F-T-G-E-A-K-F-V-V-L-P-G-E-A-G-E-L-G-I-L-P-G-H-T-P-L-I-S-R-I-R-P-G-T-V-K-I-V-R-A-D-E-G-E-E-N-I-F-V-A-G-G-I-L-E-V-Q-P-G-S-V-T-V-L-A-D-T-A-I-R-A-A-D-L-D-E-A-R-A-V-A-A-R-E-K-A-E-E-A-L-R-N-A-K-D-K-A-D-I-A-V-V-E-A-E-L-A-M-L-A-A-Q-A-V-A-A-R-K-L-R-Q-G-R-T-H"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-L-L-F-P-G-T-F-T-M-Q-T-D-Y-A-E-L-V-R-R-T-I-R-S-V-P-D-W-P-T-P-G-V-T-F-R-D-I-T-P-V-L-Q-D-P-R-T-F-R-V-L-I-D-L-F-V-Y-R-Y-M-R-Q-R-L-D-L-V-A-G-V-D-A-R-G-F-I-V-G-A-V-L-A-H-E-L-N-L-G-F-V-P-V-R-K-K-G-K-L-P-Y-R-T-V-A-E-E-Y-S-L-E-Y-G-N-A-A-V-E-M-H-T-D-S-V-R-T-G-Q-R-V-L-L-V-D-D-L-I-A-T-G-G-T-M-L-A-A-I-K-L-L-Q-R-L-G-A-N-V-V-E-A-A-A-I-I-D-L-P-Y-L-G-G-S-A-Q-I-T-A-T-G-T-P-L-Y-T-V-C-Q-Y-Q-E-G-D"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-E-E-T-L-L-A-F-D-F-G-E-K-K-I-G-I-A-I-G-N-T-L-T-R-Q-A-R-P-L-E-I-I-F-S-E-T-R-A-A-R-F-G-R-I-G-Q-L-L-Q-E-W-Q-P-Q-R-A-V-V-G-L-P-L-T-L-D-G-Q-E-Q-P-A-S-A-R-A-R-R-F-A-N-Q-L-H-G-R-F-G-L-A-V-E-L-V-D-E-R-G-S-S-M-E-A-Q-Q-L-L-G-T-H-A-A-D-D-A-V-A-A-A-V-I-L-Q-R-Y-L-D-T-L-P-Q-P"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-V-A-K-P-H-E-V-K-R-D-W-F-V-I-D-A-K-G-K-V-L-G-R-V-A-S-E-V-A-H-R-L-R-G-K-H-K-P-E-F-T-P-H-V-D-T-G-D-Y-I-V-I-I-N-A-A-D-I-V-V-T-G-N-K-A-Q-D-K-K-Y-F-R-H-T-T-Y-P-G-G-I-R-E-T-N-F-E-K-M-Q-Q-R-F-P-G-R-A-I-Q-K-A-V-K-G-M-L-P-K-G-P-L-G-Y-A-M-I-K-K-L-K-V-Y-A-G-A-E-H-P-H-T-A-Q-Q-P-K-P-L-E-F"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters ### SEQUENCE -M-N-A-V-T-E-T-V-D-L-Q-A-P-P-P-V-P-L-V-F-T-D-S-A-A-A-K-V-K-D-L-L-A-E-E-G-N-P-E-L-K-L-R-V-F-V-Q-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-V-V-N-D-D-D-T-V-L-D-K-A-G-V-Q-L-L-V-D-P-M-S-F-Q-Y-L-V-G-A-E-I-D-Y-K-E-D-L-E-G-A-Q-F-V-I-R-N-P-N-A-S-T-T-C-G-C-G-S-S-F-S-V"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-F-C-G-N-A-D-T-Q-V-V-D-S-R-V-S-E-E-G-D-T-I-R-R-R-R-R-C-L-S-C-D-K-R-F-T-T-Y-E-R-V-E-L-A-M-P-S-V-V-K-R-D-G-S-R-T-E-Y-D-A-G-K-V-R-G-S-L-S-L-A-L-R-K-R-P-V-S-T-D-E-V-D-S-A-V-A-R-I-E-E-T-L-L-A-S-G-M-R-E-V-P-S-E-Q-I-G-E-L-V-M-G-E-L-K-R-L-D-K-V-A-Y-V-R-Y-A-S-V-Y-K-S-F-E-D-I-G-E-F-V-E-A-I-R-E-M-Q-G-P-L-L-P-G-K-K-L-R-K-D"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-L-D-R-E-G-Y-R-P-N-V-G-I-I-L-V-N-G-K-N-E-V-F-W-G-K-R-I-R-E-H-A-W-Q-F-P-Q-G-G-I-K-Y-G-E-S-P-V-Q-A-M-Y-R-E-L-H-E-E-V-G-L-K-P-E-H-V-R-I-L-G-R-T-R-D-W-L-R-Y-N-V-P-D-H-F-V-R-R-E-W-R-G-H-Y-K-G-Q-K-Q-I-W-F-L-L-R-L-V-G-R-D-S-D-V-C-L-R-A-T-Q-H-P-E-F-D-A-W-R-W-S-Q-Y-W-V-P-L-D-A-V-I-E-F-K-R-D-V-Y-T-Q-A-L-N-E-L-A-V-I-L-F-R-R-H-H-E-T-R-Y-L-R-Q-R-V-H-G-P-R-S-T-D-S-P-S-S-E-T-D-G-H-A-H-I-A-G"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-H-A-I-L-K-M-G-D-P-R-L-L-R-V-A-A-P-V-E-R-Y-D-T-P-E-L-R-A-L-I-D-D-M-F-E-T-M-A-H-A-Q-G-V-G-L-A-A-P-Q-I-G-V-D-L-Q-L-V-I-F-G-F-E-R-N-D-R-Y-P-D-A-P-A-V-P-R-T-I-L-C-N-P-V-I-E-P-L-S-G-E-M-E-D-G-W-E-G-C-L-S-V-P-G-L-R-G-L-V-P-R-Y-R-H-I-R-Y-S-G-Y-D-P-A-G-Q-R-I-E-R-E-A-E-G-F-H-A-R-V-V-Q-H-E-C-D-H-L-I-G-R-L-Y-P-T-R-I-R-D-L-T-K-F-G-Y-T-E-V-L-F-P-E-M-D-P-N-A-D"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-F-L-S-F-L-L-G-Q-K-K-S-S-A-S-V-A-K-E-R-L-Q-I-I-L-A-H-E-R-G-R-G-D-S-P-D-Y-L-P-Q-L-Q-Q-E-L-V-A-V-I-S-K-Y-V-K-I-D-P-E-D-I-K-V-H-L-E-R-Q-D-T-L-E-V-L-E-V-K-I-E-M-P-Q-N"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-I-T-G-T-L-I-E-K-S-P-P-V-V-C-V-D-V-N-G-V-G-Y-E-I-D-V-P-M-S-T-L-Y-A-L-P-E-T-G-A-R-V-T-L-F-T-H-L-V-V-R-E-D-A-Q-L-L-Y-G-F-G-S-S-A-E-R-S-T-F-R-E-L-I-K-V-T-G-I-G-A-R-T-A-L-A-V-L-S-G-L-S-V-A-E-L-S-Q-A-I-T-L-Q-E-T-G-R-L-T-R-V-P-G-I-G-K-K-T-A-E-R-L-L-L-E-M-R-G-K-L-G-A-D-I-G-A-T-P-H-A-A-S-G-H-Q-S-D-I-L-N-A-L-L-A-L-G-Y-S-D-K-E-S-Q-A-A-L-K-K-L-P-D-G-V-D-V-S-E-G-I-R-L-A-L-K-A-L-V-R"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-A-P-Q-E-P-V-D-S-T-P-E-S-G-E-N-A-A-T-P-G-L-E-D-D-L-S-A-E-L-A-A-L-R-A-E-L-E-A-A-Q-A-T-V-K-A-Q-Q-E-Q-V-L-R-A-A-A-E-A-E-N-V-R-R-R-A-Q-E-D-V-A-K-A-R-K-F-G-I-E-S-F-A-E-S-L-V-P-V-K-D-S-L-E-A-A-L-A-Q-P-D-Q-A-A-Q-A-W-R-E-G-V-E-V-T-L-K-Q-L-T-A-A-F-E-R-N-L-L-K-E-I-A-P-A-Q-G-D-K-F-D-P-H-L-H-Q-A-I-S-S-V-P-A-D-Q-P-A-N-T-V-L-Q-L-L-Q-K-G-Y-V-I-A-D-R-T-L-R-P-A-L-V-V-V-S-A-G-Q-G"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-L-I-A-I-L-E-Q-E-E-I-A-R-L-T-G-G-N-A-V-T-E-F-A-P-G-D-T-V-V-V-S-V-N-V-V-E-G-T-R-K-R-V-Q-A-F-E-G-V-V-I-A-K-R-N-R-G-L-N-S-S-F-I-V-R-K-I-S-S-G-E-A-V-E-R-T-F-Q-L-Y-S-P-Q-I-A-G-I-E-V-K-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-S-R-S-G-K-S-A-R-I-K-E-K-L-V-L-K-K-A-K-S-A"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-A-N-E-N-R-L-V-W-L-D-M-E-M-T-G-L-D-P-E-K-E-R-I-I-E-V-A-V-V-V-T-E-A-D-L-T-V-V-A-E-G-P-V-L-V-V-H-Q-P-D-S-L-L-D-A-M-D-N-W-N-K-S-T-H-G-K-S-G-L-I-E-K-V-K-A-S-T-L-G-E-A-Q-A-E-Q-I-L-L-E-F-L-A-E-H-V-P-A-G-K-S-P-L-C-G-N-T-I-S-Q-D-R-R-F-M-Y-A-Y-M-P-N-L-E-R-F-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-A-R-R-W-A-P-A-V-Y-K-G-F-D-K-K-S-R-H-E-A-L-A-D-I-Y-E-S-I-D-E-L-K-Y-Y-R-E-H-L-L-K-V"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-S-S-V-S-A-A-G-A-T-P-P-A-S-P-G-C-I-A-G-I-G-M-D-L-L-R-I-E-R-I-E-R-A-L-A-R-H-G-D-R-F-A-Q-K-I-L-G-P-E-E-L-A-K-F-H-A-R-R-R-R-D-P-A-R-G-V-R-F-L-A-T-R-F-A-A-K-E-A-F-S-K-A-I-G-L-G-M-R-M-P-M-S-W-R-R-V-Q-T-L-N-A-P-G-G-R-P-V-L-V-I-G-A-E-L-A-D-W-F-D-A-R-F-G-A-A-H-V-S-I-T-D-E-S-D-M-A-A-A-Y-V-I-V-E-R-K-P-A-P-D-G-R-P"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-T-F-A-P-L-N-F-L-A-I-G-V-G-A-T-L-G-A-W-L-R-W-V-L-G-L-R-L-N-G-A-G-W-P-W-G-T-L-T-A-N-L-V-G-G-Y-L-I-G-V-M-V-A-L-I-A-S-H-P-E-W-P-A-W-I-R-L-A-A-V-T-G-F-L-G-G-L-T-T-F-S-T-F-S-A-E-T-V-D-M-L-E-R-G-V-Y-A-T-A-A-A-Y-A-G-A-S-L-A-G-S-L-A-M-T-G-L-G-L-A-T-V-R-L-L-L-R"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-D-L-F-A-L-T-E-E-A-L-A-G-M-D-I-E-L-V-D-V-E-R-A-A-M-G-L-L-R-V-T-I-D-R-V-D-G-V-R-I-E-D-C-E-Q-V-S-R-Q-L-S-R-V-Y-E-V-E-N-I-D-Y-K-R-L-E-V-G-S-P-G-V-D-R-P-L-R-N-E-A-E-F-R-R-F-A-G-E-R-I-E-I-K-L-R-E-A-L-D-G-R-K-V-F-S-G-T-L-R-A-P-E-A-D-G-A-S-G-Q-D-D-T-A-G-A-G-K-A-V-F-G-L-E-F-E-A-K-K-N-D-I-Q-V-L-S-F-T-L-D-D-I-E-R-A-K-L-D-P-V-L-D-F-K-G-K-K-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-R-H-K-S-K-S-I-P-G-R-N-L-R-L-A-D-Q-I-Q-K-D-L-A-G-I-I-Q-R-E-I-D-M-T-R-A-G-L-I-T-L-S-G-V-E-L-S-A-D-Y-A-H-A-K-V-Y-F-T-V-L-G-A-E-P-D-T-A-A-A-L-L-N-E-K-A-G-W-L-H-S-Q-L-Y-K-L-L-H-I-H-T-V-P-T-L-R-F-V-H-D-P-Q-I-T-R-G-I-E-M-S-M-L-I-D-R-A-N-R-P-G-P-H-S-G-V-P-D-E-P-E-D-Q-S"} +{"text": "### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate with acetyl coenzyme A ### SEQUENCE -M-R-K-D-E-T-S-N-T-S-P-D-I-S-A-A-Q-P-A-S-A-L-R-Y-Q-L-R-P-P-R-R-N-D-G-A-A-I-H-Q-L-V-S-E-C-P-P-L-D-L-N-S-L-Y-A-Y-L-L-L-C-E-H-H-A-H-T-C-V-V-A-E-S-P-G-G-R-I-D-G-F-V-S-A-Y-L-L-P-T-R-P-D-V-L-F-V-W-Q-V-A-V-H-S-R-A-R-G-H-R-L-G-R-A-M-L-G-H-I-L-E-R-Q-E-C-R-H-V-R-H-L-E-T-T-V-G-P-D-N-Q-A-S-R-R-T-F-A-G-L-A-G-E-R-G-A-H-V-S-E-Q-P-F-F-D-R-Q-A-F-G-G-A-D-H-D-D-E-M-L-L-R-I-G-P-F-T-H-P-P-H"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-R-N-V-K-D-V-M-G-T-E-D-E-V-R-T-D-T-W-V-S-R-R-V-L-L-K-K-D-G-M-G-F-S-F-H-E-T-T-I-F-P-G-T-R-T-H-I-H-Y-K-N-H-L-E-A-V-W-C-I-E-G-D-G-S-I-E-T-I-A-D-G-K-T-Y-E-L-G-P-G-V-V-Y-A-L-N-E-N-D-E-H-W-L-C-G-G-K-Q-P-L-R-V-I-C-V-F-N-P-P-L-T-G-Q-E-V-H-D-A-E-G-V-Y-A-L-V-E-E-A-A"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-S-N-K-G-Q-T-L-Q-D-P-F-L-N-T-L-R-K-E-H-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-Y-V-V-L-L-R-N-T-V-T-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-A-V-N-F-Q-V-E-V-P-A-E"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-V-E-D-C-L-N-Q-I-P-N-R-F-K-L-T-L-A-A-T-Y-R-A-R-E-L-A-Q-G-H-A-P-R-L-D-S-K-D-K-P-T-V-T-A-L-R-E-I-A-S-G-L-T-G-L-E-M-L-R-K-V-P-T"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-I-I-D-N-R-K-A-T-H-D-Y-F-I-E-D-R-Y-E-A-G-M-V-L-E-G-W-E-V-K-A-I-R-D-G-R-V-Q-L-K-E-S-Y-V-I-V-R-D-G-E-I-Y-L-L-G-M-H-V-S-P-L-P-T-A-S-T-H-I-R-P-D-A-T-R-T-R-K-L-L-L-K-A-E-E-I-R-K-L-I-G-K-V-E-Q-R-G-Y-T-L-V-P-L-N-L-H-Y-K-N-G-R-I-K-L-D-F-A-L-G-R-G-K-K-L-Y-D-K-R-D-T-A-R-E-K-D-W-Q-R-E-K-E-R-V-L-K-H-D-T-R-V-N-Q-R-D-S"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-V-A-D-I-R-K-S-A-E-T-R-M-A-K-S-L-E-T-L-K-A-S-L-A-K-I-R-T-G-R-A-H-T-G-I-L-D-H-V-Q-V-E-Y-Y-G-S-P-V-P-I-S-Q-V-A-N-V-N-L-V-D-A-R-T-I-S-V-Q-P-Y-E-K-S-M-A-G-P-I-E-K-A-I-R-E-S-D-L-G-L-N-P-V-S-M-G-E-T-I-R-V-P-M-P-A-L-T-E-E-R-R-R-D-L-T-K-V-V-K-S-E-G-E-D-A-K-V-A-V-R-N-L-R-R-E-A-N-E-A-L-K-K-L-V-K-D-K-E-I-S-E-D-D-E-R-R-A-Q-D-D-V-Q-K-L-T-D-R-A-V-G-D-I-D-K-M-I-V-Q-K-E-A-E-I-M-T-V"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-T-T-P-I-P-L-A-R-G-W-L-P-A-A-P-S-T-L-D-P-L-R-K-Y-W-L-F-R-P-G-A-L-T-A-G-L-R-Q-L-G-H-V-R-L-R-V-L-A-E-Y-P-T-G-A-P-R-D-E-A-D-G-M-R-I-A-A-Q-S-P-V-W-V-R-E-V-L-M-S-I-D-G-V-D-S-V-V-A-R-S-L-T-P-L-R-A-S-H-G-V-W-Q-G-M-R-R-L-L-T-R-P-L-A-D-M-L-Y-H-D-P-G-I-H-R-S-V-F-V-C-R-R-L-A-A-G-V-P-F-H-A-T-A-I-A-R-A-P-A-G-G-P-E-P-A-L-W-A-R-R-S-A-F-W-R-A-G-Q-P-L-L-V-A-E-C-F-L-P-A-F-W-S-L-A-R-A-P-V-A-P-R"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-A-A-D-D-H-F-S-L-F-G-L-P-T-R-F-A-L-D-P-V-Q-L-E-Q-A-W-R-A-V-A-A-R-V-H-P-D-R-Y-A-T-A-S-A-A-E-R-R-V-A-M-Q-W-A-A-R-A-N-E-A-Y-R-Q-L-R-D-P-M-L-R-A-R-Y-L-C-E-Q-A-G-V-D-L-Q-T-E-S-N-T-A-M-D-P-A-F-L-M-Q-Q-M-E-W-R-E-M-L-D-D-A-R-R-D-P-A-A-F-A-A-L-R-A-E-L-E-Q-A-R-L-R-M-Q-Q-T-L-S-E-L-I-D-E-R-G-D-Y-Q-Q-A-G-T-K-V-R-E-W-M-F-V-E-K-L-A-Q-E-L-S-A-A-Q-P-M-Q"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-S-V-D-L-K-I-L-D-A-R-M-R-E-Y-L-P-A-Y-A-T-P-G-S-A-G-L-D-L-R-A-C-T-E-A-S-L-V-I-E-P-G-Q-T-V-L-V-P-T-G-L-A-I-H-I-G-D-P-R-Y-A-A-M-I-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-Q-L-M-V-S-T-W-N-R-G-T-Q-P-F-T-L-D-P-M-E-R-L-A-Q-L-V-I-V-P-V-Q-Q-V-A-F-N-V-V-E-D-F-D-A-S-E-R-G-A-G-G-F-G-S-T-G-R-A"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-R-L-I-G-L-D-G-E-Q-L-G-I-V-K-I-A-D-A-F-R-L-S-E-Q-S-D-V-D-L-V-E-I-A-P-N-A-D-P-P-V-C-R-L-M-D-Y-G-K-F-K-Y-Q-E-Q-K-R-Q-A-E-A-R-S-K-Q-K-V-I-Q-V-K-E-V-K-F-R-P-A-T-D-E-G-D-Y-Q-V-K-L-R-N-L-R-R-F-L-E-E-G-D-K-A-K-V-T-L-R-F-R-G-R-E-M-A-H-Q-E-L-G-M-R-V-L-E-R-V-R-D-D-L-I-E-L-A-Q-V-E-A-M-P-K-L-E-G-R-Q-M-V-M-V-L-A-P-R-K-K-A-V-G-K-P-D-A-A-G"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-G-T-T-M-L-A-E-P-R-T-L-T-K-A-E-L-A-E-L-L-F-E-R-V-G-L-N-K-R-E-A-K-D-I-V-D-T-F-F-E-E-I-R-D-A-L-A-R-G-D-S-V-K-L-S-G-F-G-N-F-Q-V-R-D-K-P-P-R-P-G-R-N-P-K-T-G-E-T-I-P-I-A-A-R-R-V-V-T-F-H-A-S-Q-K-L-K-S-V-V-E-Q-P-S-S-P-P-D-P-A-S-A-E"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-R-A-R-H-K-K-V-I-A-A-A-K-G-Y-R-G-R-R-G-N-V-F-R-I-A-K-Q-A-V-M-R-A-G-Q-Y-A-Y-R-D-R-R-N-K-K-R-T-F-R-A-L-W-I-T-R-I-N-A-A-V-R-E-Q-G-M-S-Y-S-V-F-I-A-G-L-K-K-A-A-I-E-L-D-R-K-V-L-A-D-L-A-V-R-D-K-A-G-F-A-A-I-V-Q-Q-A-K-A-A-L-A-A"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-S-T-L-D-T-Q-H-D-V-V-V-E-K-Q-P-A-R-T-A-P-P-P-M-Y-Q-V-V-L-L-N-D-D-Y-T-P-M-E-F-V-V-K-V-L-Q-K-F-F-G-K-N-S-E-D-A-T-R-I-M-L-Q-V-H-H-E-G-R-A-V-C-G-V-Y-P-R-D-L-A-A-T-R-I-A-Q-V-S-Q-Y-A-R-A-R-Q-H-P-L-Q-C-I-M-E-P-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-A-Q-A-R-K-R-A-R-Q-S-V-Q-R-N-K-H-N-S-S-L-R-S-M-L-R-T-A-I-K-R-V-R-Q-S-I-A-T-G-D-K-A-A-A-G-E-T-L-R-K-A-T-S-V-I-D-S-V-A-D-K-N-I-I-H-K-N-K-A-A-R-H-K-S-R-L-A-A-A-V-K-A-L-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-E-K-V-A-N-L-G-N-L-G-E-V-V-R-V-R-D-G-Y-A-R-N-F-L-I-P-Q-K-K-A-R-R-A-T-D-A-A-L-K-E-F-E-A-R-R-A-E-L-E-K-V-Q-A-E-K-L-A-A-A-Q-A-L-A-E-R-L-N-G-F-Q-L-K-I-S-Q-K-A-G-V-D-G-R-L-F-G-S-V-T-N-A-D-V-A-E-G-L-R-K-A-G-F-E-A-V-E-K-S-Q-V-R-M-P-N-G-Q-I-K-A-V-G-E-Y-P-V-Q-A-V-L-H-A-D-V-V-A-D-V-V-V-L-V-E-G-E-M-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-F-F-G-K-R-K-E-K-R-K-F-T-Q-Q-N-P-L-F-K-R-R-K-F-C-R-F-T-A-A-G-V-E-E-I-D-Y-K-D-L-D-T-L-R-D-F-V-Q-E-N-G-K-I-I-P-A-R-L-T-G-T-R-A-I-Y-Q-R-Q-L-D-T-A-I-K-R-A-R-F-L-A-L-L-P-Y-T-D-N-H-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-V-V-F-I-V-H-P-D-Q-S-E-Q-V-P-A-M-V-E-R-Y-Q-A-L-V-T-G-Q-S-G-T-V-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-Q-K-L-V-K-A-H-Y-V-C-M-N-I-E-C-G-Q-A-T-L-D-E-L-E-H-S-F-R-Y-N-D-A-V-L-R-H-L-V-I-K-T-K-K-A-P-A-A-P-S-I-M-M-K-S-V-E-R-E-E-A-R-K-A-S-A-E-A-A-A-T-A-T-A-A-E"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-S-S-K-Q-A-D-P-Q-T-D-A-R-P-L-P-Q-D-F-E-T-A-L-A-E-L-E-S-L-V-S-A-M-E-N-G-T-L-P-L-E-Q-S-L-S-A-Y-R-R-G-V-E-L-A-R-V-C-Q-D-R-L-A-Q-A-E-Q-Q-V-K-V-L-E-G-D-L-L-R-P-L-D-P-A-A-L-D-D-E"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-T-R-I-G-L-L-G-G-S-F-D-P-V-H-V-A-H-I-A-L-A-D-T-A-R-Q-F-L-G-L-D-Q-V-Q-L-I-P-A-A-N-P-W-Q-R-Q-P-L-K-A-S-A-P-H-R-L-R-M-L-E-L-A-I-A-G-H-P-A-L-A-I-N-P-V-E-I-E-R-G-G-A-T-Y-T-A-D-T-V-R-A-L-P-G-G-P-Q-Y-F-W-L-L-G-T-D-Q-L-Q-N-F-C-T-W-R-D-W-Q-D-I-A-A-R-I-E-L-A-V-A-T-R-P-G-A-S-I-A-P-P-A-E-L-A-T-W-L-A-A-H-R-R-Q-L-H-E-L-P-F-A-P-M-A-V-S-A-S-D-I-R-Q-R-L-A-A-G-A-A-T-D-G-L-L-P-E-P-V-A-A-Y-I-A-T-H-H-L-Y-R"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-L-I-V-A-A-V-G-T-R-M-P-G-W-V-E-T-A-W-D-D-Y-A-K-R-L-P-A-D-C-A-L-E-L-R-E-I-K-P-E-P-R-T-S-G-K-T-P-A-Q-M-M-A-A-E-A-R-R-I-E-T-A-L-P-P-G-V-L-R-I-A-L-D-E-R-G-R-D-L-T-T-V-A-L-S-Q-Q-L-E-K-W-R-A-G-G-R-D-V-A-F-L-V-G-G-P-D-G-L-D-A-A-L-K-A-S-C-E-G-L-L-R-L-S-S-L-T-L-P-H-P-M-V-R-V-L-L-A-E-Q-L-Y-R-A-W-A-I-M-T-N-H-P-Y-H-R-A"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-T-A-Q-E-L-R-V-G-N-V-I-M-V-G-K-D-P-L-V-V-Q-K-T-E-Y-N-K-S-G-R-N-A-A-V-V-K-L-K-F-K-N-L-L-T-G-S-G-S-E-S-V-Y-K-A-D-E-K-F-D-V-V-V-L-E-R-K-E-C-T-Y-S-Y-F-G-D-P-M-Y-V-F-M-D-E-E-Y-N-Q-Y-E-I-E-A-D-S-M-G-D-A-L-N-Y-L-E-E-A-M-P-V-E-V-V-F-Y-D-G-R-A-I-S-V-E-L-P-T-I-L-V-R-E-I-T-Y-T-E-P-A-V-R-G-D-T-S-G-K-V-L-K-P-A-K-I-N-T-G-F-E-L-S-V-P-L-F-C-A-I-G-D-K-I-E-I-D-T-R-T-N-E-Y-R-S-R-V-N"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-K-G-Q-L-A-G-L-M-R-Q-A-Q-Q-M-Q-E-N-M-K-K-A-Q-D-A-L-A-E-I-Q-V-E-G-A-A-G-G-G-L-V-K-V-T-M-T-C-R-H-D-V-K-R-V-A-I-D-P-S-L-L-G-E-D-K-D-M-L-E-D-L-V-A-A-A-F-N-D-A-L-R-K-A-E-A-T-S-Q-E-K-M-A-S-V-T-A-G-M-P-L-P-P-G-M-K-L-P-F"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-L-I-E-L-N-G-I-V-D-E-V-L-P-D-S-R-Y-R-V-K-L-D-N-G-I-E-V-G-A-Y-A-S-G-R-M-R-K-H-R-I-R-I-L-A-G-D-R-V-T-L-E-M-S-P-Y-D-L-T-K-G-R-I-N-F-R-H-K-D-E-R-S-G-P-P-S-R-P-P-Q-H-R-R"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-T-E-L-S-L-S-V-Q-Y-G-V-A-D-A-R-L-P-R-W-R-L-R-R-W-V-Q-Y-A-L-A-G-A-A-G-D-G-H-A-G-L-A-G-A-E-L-G-L-R-L-V-G-L-A-E-G-R-R-L-N-R-E-F-R-G-R-D-Y-A-T-N-V-L-T-F-E-Y-G-T-G-P-D-G-V-A-R-G-D-I-V-V-C-V-P-V-L-A-R-E-A-R-E-Q-R-K-T-L-L-D-H-A-A-H-L-T-V-H-G-T-L-H-A-L-G-Y-D-H-I-K-A-G-E-A-R-R-M-E-A-L-E-T-A-V-L-A-R-M-G-I-A-D-P-Y-L-A-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-Q-A-R-A-N-A-R-S-A-R-R-R-A-R-E-F-A-L-Q-G-V-Y-A-W-L-L-R-G-G-E-G-T-Q-D-A-G-E-I-D-A-H-L-R-D-A-E-D-F-S-E-A-D-A-Q-W-F-K-T-L-L-H-G-V-L-R-E-A-P-V-L-R-E-R-F-L-P-Y-I-D-R-P-L-A-E-L-S-P-V-E-H-G-I-L-L-I-G-S-F-E-L-M-H-H-V-E-V-P-Y-K-V-A-I-N-E-A-V-E-L-A-K-S-F-G-G-T-D-G-F-K-F-V-N-G-V-L-D-K-L-A-A-D-V-R-T-A-E-V-Q-A-A-P-R-R"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-N-P-Y-I-L-T-P-D-L-N-G-E-G-L-H-I-G-I-V-R-A-R-F-N-E-E-I-G-Q-A-Q-L-Q-A-C-L-E-E-L-G-K-L-G-V-D-E-R-D-V-M-V-V-S-V-P-G-A-L-E-L-G-V-A-L-A-R-M-A-E-S-Y-E-F-D-A-L-I-A-L-G-A-V-I-R-G-E-T-Y-H-F-E-V-V-S-N-E-S-A-A-A-I-S-R-I-A-L-E-T-G-I-P-V-A-N-G-V-L-T-V-D-T-D-E-Q-A-Q-A-R-A-A-G-K-G-A-D-C-A-Q-V-A-V-E-M-A-N-L-A-A-A-L-E-P-E-E-D-D-E-D-E-D-D-E-D-E-D-F-D-D-E-E-D-D-G-R"} +{"text": "### FUNCTION Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein ### SEQUENCE -M-S-A-C-P-A-P-R-S-P-F-R-W-L-H-A-F-T-L-C-L-L-L-A-V-L-A-G-C-V-S-V-P-K-P-M-A-G-A-G-E-D-V-F-S-R-V-G-R-F-A-I-T-V-T-E-S-D-G-K-Q-Q-A-V-Q-G-G-F-A-W-R-D-D-G-G-S-Y-L-L-D-L-T-N-P-L-G-S-T-E-A-R-V-E-G-R-P-G-M-A-V-L-T-R-A-N-G-E-R-L-A-A-E-H-P-D-A-L-A-E-D-A-L-G-S-P-V-P-V-T-G-L-R-D-W-L-R-G-R-L-M-A-G-A-A-P-D-G-L-E-R-D-A-Q-G-R-P-T-A-F-E-Q-D-G-W-N-A-R-L-S-R-Y-D-A-Q-G-P-Q-L-L-V-L-Q-R-Q-E-P-G-R-R-I-L-V-R-L-V-I-T-Q-P"} +{"text": "### FUNCTION Dephosphorylates the 5' and 2'-phosphates of deoxyribonucleotides ### SEQUENCE -M-L-I-L-L-D-Q-D-G-V-L-A-D-F-E-H-A-F-I-D-A-W-R-K-R-H-P-D-I-E-P-V-A-F-K-D-R-K-S-F-H-I-R-E-D-Y-A-P-E-L-R-G-L-A-E-A-I-Y-T-A-P-G-F-I-R-D-L-P-P-V-P-G-A-I-E-A-F-R-E-L-L-A-L-G-M-D-V-R-I-C-S-S-P-L-M-Q-F-E-N-C-V-A-E-K-Y-L-W-V-E-R-H-L-G-R-E-A-T-Q-R-L-I-L-T-R-D-K-T-L-V-Q-G-D-L-L-I-D-D-R-P-V-I-T-G-A-A-R-P-R-W-R-H-I-I-Y-D-A-P-Y-N-R-D-Q-T-D-R-P-R-L-D-W-R-N-W-R-N-V-L-A-G-E-L-Y-R-S-D-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-K-T-G-G-K-Q-Y-R-V-A-T-G-E-K-L-K-V-E-Q-I-P-A-D-I-G-Q-E-I-T-L-D-Q-V-L-S-V-G-E-G-D-Q-L-K-V-G-T-P-L-V-S-G-A-V-V-K-A-T-V-L-A-H-G-R-H-D-K-I-K-I-F-K-M-R-R-R-K-H-Y-Q-K-H-Q-G-H-R-Q-N-Y-T-E-I-R-I-E-A-I-T-A"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-A-D-Q-D-Q-T-N-Q-Q-A-G-S-D-A-P-S-F-N-L-Q-R-V-Y-L-K-D-L-S-L-E-M-P-N-A-P-H-V-F-L-E-Q-E-A-P-Q-V-E-V-S-I-N-V-G-G-Q-R-L-A-E-T-V-F-E-S-T-V-T-V-T-V-T-T-R-V-N-D-K-V-L-Y-L-V-E-G-T-Q-A-G-I-F-E-L-A-N-I-P-A-E-Q-M-D-P-L-L-G-I-V-C-P-T-M-L-Y-P-Y-L-R-A-N-V-A-D-A-I-T-R-T-S-L-P-A-L-H-L-A-E-V-N-F-Q-A-L-Y-E-Q-R-L-A-E-M-A-Q-Q-Q-P-D-A-A-N-G-N-D-S-G-I-I-L-P-P-G-A-T-R-Q"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-L-L-S-I-L-R-Y-P-D-P-R-L-H-K-T-A-K-P-V-A-V-V-D-D-R-I-R-Q-L-V-R-D-M-A-D-T-M-Y-D-A-P-G-V-G-L-A-A-T-Q-V-D-V-H-E-R-V-V-V-I-D-V-S-E-E-G-N-D-L-R-V-L-I-N-P-E-I-T-W-K-S-D-E-R-Q-T-Y-E-E-G-C-L-S-V-P-G-I-Y-D-E-V-E-R-A-A-R-I-R-C-K-A-L-D-Q-Q-G-Q-P-Y-E-F-E-A-D-G-L-L-A-V-C-V-Q-H-E-I-D-H-L-D-G-K-V-F-V-E-Y-L-S-N-L-K-Q-N-R-I-K-T-K-L-K-K-A-E-R-E-A-E-R-A"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-T-E-T-E-F-L-A-L-V-D-Q-V-L-D-S-I-E-S-Q-A-D-D-W-A-A-G-L-D-V-D-I-E-A-T-R-S-G-N-V-L-T-L-V-F-E-D-G-T-Q-V-V-V-N-A-Q-A-A-M-Q-E-L-W-V-A-A-R-S-G-G-F-H-Y-R-Y-D-G-Q-H-W-N-D-T-R-G-G-P-R-L-P-D-A-L-S-Q-I-C-S-E-A-A-G-V-P-V-S-V-R-L"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-A-S-T-S-G-A-S-R-V-R-K-K-V-K-K-N-V-S-D-G-I-A-H-V-H-A-S-F-N-N-T-I-I-T-I-T-D-R-Q-G-N-A-L-S-W-A-T-S-G-G-A-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-T-A-G-R-V-A-M-E-Y-G-I-K-T-L-E-V-R-I-K-G-P-G-P-G-R-E-S-S-V-R-A-L-N-A-L-G-I-K-I-S-S-I-A-D-I-T-P-V-P-H-N-G-C-R-P-P-K-R-R-R-I"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-P-Q-Q-H-A-E-I-G-L-T-A-I-F-G-I-G-R-T-R-A-R-K-I-C-E-A-A-G-V-P-V-T-K-K-V-K-D-L-T-D-A-E-L-E-R-I-R-E-H-I-G-V-F-A-V-E-G-D-L-R-R-E-V-Q-L-S-I-K-R-L-I-D-L-G-T-Y-R-G-M-R-H-K-R-G-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-R-A-A-A-S-L-K-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-V-I-Q-M-Q-G-E-V-L-E-N-L-P-N-A-T-F-R-V-K-L-E-N-G-H-V-V-L-G-H-I-S-G-K-M-R-M-H-Y-I-R-I-L-P-G-D-K-V-T-V-E-L-T-P-Y-D-L-T-R-A-R-I-V-F-R-S-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-S-D-I-Q-L-N-T-L-K-P-A-E-G-S-K-H-A-K-R-R-V-G-R-G-I-G-S-G-L-G-K-T-A-G-R-G-H-K-G-Q-K-S-R-S-G-G-F-H-K-V-G-F-E-G-G-Q-M-P-L-Q-R-R-L-P-K-R-G-F-T-P-L-G-Q-H-L-Y-A-E-V-R-L-S-E-L-Q-L-M-E-A-E-E-I-D-V-Q-A-L-K-A-A-G-V-V-G-Q-S-V-R-Y-A-K-V-I-K-S-G-E-L-S-R-K-V-V-L-R-G-I-T-A-T-A-G-A-R-A-A-I-E-A-A-G-G-S-L-A"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-T-K-V-Q-G-K-H-A-A-E-K-E-N-D-D-G-L-R-E-K-M-I-A-V-N-R-V-S-K-V-V-K-G-G-R-T-M-S-F-A-A-L-S-V-V-G-D-G-D-G-R-I-G-M-G-K-G-K-A-R-E-V-P-V-S-V-Q-K-A-M-E-Q-A-R-R-G-M-F-K-V-A-L-K-N-G-T-L-H-H-T-V-V-G-K-H-G-A-S-T-V-L-I-S-P-A-A-E-G-T-G-V-I-A-G-G-P-M-R-A-I-F-E-V-M-G-V-R-N-V-V-A-K-S-L-G-S-S-N-P-Y-N-L-V-R-A-T-L-N-G-L-R-A-S-L-T-P-A-E-V-A-A-K-R-G-K-S-V-E-E-I-L-G"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-V-S-R-L-R-R-A-V-P-T-R-R-K-I-A-Q-L-R-V-H-R-L-S-V-F-R-S-N-L-H-I-Y-A-N-I-I-S-P-E-G-D-R-V-L-V-S-A-S-T-L-E-A-E-V-R-A-Q-L-G-G-A-G-K-G-G-N-A-T-A-A-A-L-V-G-K-R-V-A-E-K-A-K-A-A-G-I-E-L-V-A-F-D-R-S-G-F-R-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-A-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-A-K-Y-P-V-E-L-P-K-G-V-E-A-S-I-Q-P-D-Q-I-T-V-K-G-P-L-G-T-L-V-Q-S-L-T-G-D-V-N-V-A-Q-E-D-G-K-L-T-F-V-V-A-N-D-S-R-H-A-N-A-M-S-G-T-L-R-A-L-V-A-N-M-V-T-G-V-S-K-G-F-E-R-K-L-N-L-V-G-V-G-Y-R-A-Q-I-Q-G-D-A-V-K-L-Q-L-G-F-S-H-D-V-V-H-Q-L-P-A-G-V-K-A-E-C-P-T-Q-T-E-I-V-I-K-G-P-N-K-Q-V-V-G-Q-V-A-A-E-I-R-K-Y-R-E-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-R-V-V-I-K-E-T-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-S-D-P-I-A-D-M-L-T-R-I-R-N-A-Q-Q-V-D-K-T-T-V-T-M-P-A-S-K-L-K-V-A-I-A-T-V-L-K-D-E-G-Y-I-D-G-Y-S-V-K-G-T-Q-A-K-P-E-L-E-I-T-L-K-Y-Y-A-G-R-P-V-I-E-R-I-E-R-V-S-R-P-G-L-R-I-Y-K-G-R-T-S-I-P-Q-V-M-N-G-L-G-V-A-I-V-S-T-S-R-G-V-M-T-D-R-K-A-R-A-N-G-V-G-G-E-V-L-C-Y-V-A"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-L-S-L-I-N-R-D-I-K-R-A-K-L-A-D-K-Y-A-A-K-R-A-E-L-K-A-I-I-D-D-Q-S-K-T-D-E-E-R-Y-Q-A-R-L-K-L-Q-Q-L-P-R-N-A-N-P-T-R-Q-R-N-R-C-V-V-T-G-R-P-R-G-V-F-R-K-F-G-L-T-R-H-K-L-R-E-M-A-M-K-G-E-V-P-G-M-T-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-R-L-Q-E-F-Y-K-S-K-V-V-A-D-L-Q-A-K-F-G-Y-K-C-V-M-E-V-P-R-I-T-K-I-T-L-N-M-G-V-S-E-A-V-A-D-K-K-V-I-E-H-A-V-S-D-L-T-K-I-S-G-Q-K-P-V-V-T-K-T-R-K-A-I-A-G-F-K-I-R-E-N-Y-P-I-G-C-M-V-T-L-R-G-Q-R-M-Y-E-F-L-D-R-L-V-A-V-A-L-P-R-V-R-D-F-R-G-I-S-G-R-A-F-D-G-R-G-N-Y-N-I-G-V-K-E-Q-I-I-F-P-E-I-E-Y-D-K-I-D-A-L-R-G-L-N-I-S-I-T-T-T-A-K-T-D-D-E-A-K-A-L-L-T-A-F-S-F-P-F-R-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-N-N-I-R-K-G-D-E-V-I-V-L-T-G-R-D-K-K-R-R-G-T-V-L-A-R-V-D-A-D-H-V-L-V-E-G-V-N-V-V-K-K-H-V-K-A-N-P-M-A-N-N-P-G-G-I-V-E-K-T-M-P-I-H-V-S-N-V-A-L-F-N-P-A-T-G-K-G-D-R-V-G-V-Q-E-V-D-G-R-K-V-R-V-F-R-S-N-G-A-V-V-G-A-K-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-T-L-D-V-A-D-N-T-G-A-R-A-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-G-I-G-D-I-I-K-V-S-V-K-D-A-A-P-R-G-R-V-K-K-G-E-I-Y-N-A-V-V-V-R-T-A-K-G-V-R-R-K-D-G-S-L-I-R-F-G-G-N-A-A-V-L-L-N-A-K-L-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-R-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-T-Q-N-T-Q-V-A-K-R-Q-R-T-L-V-G-K-V-V-S-N-K-M-D-K-T-V-V-V-L-V-E-R-R-V-K-H-P-I-F-G-K-I-I-M-R-S-A-K-Y-K-A-H-D-E-S-N-Q-Y-N-E-G-D-T-V-E-I-A-E-G-R-P-I-S-R-S-K-A-W-R-V-V-R-L-V-E-A-A-R-V-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-S-R-R-K-Y-R-K-E-Q-K-G-R-N-T-G-L-A-S-R-G-T-H-V-S-F-G-E-F-G-L-K-A-T-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-I-N-R-H-I-K-R-G-G-R-I-W-I-R-I-F-P-D-K-P-I-S-Q-K-P-A-E-V-R-M-G-N-G-K-G-N-P-E-Y-W-V-A-E-I-Q-P-G-K-V-L-Y-E-M-E-G-V-S-E-E-L-A-R-E-A-F-R-L-A-A-A-K-L-P-I-S-T-T-F-V-A-R-H-I-G-A"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-T-A-I-I-R-G-V-H-I-S-A-Q-K-T-R-L-V-A-D-L-I-R-G-K-S-V-A-Q-A-L-N-I-L-T-F-S-P-K-K-A-A-V-I-L-K-K-A-V-E-S-A-I-A-N-A-E-H-N-D-G-A-D-I-D-E-L-K-V-T-T-I-F-V-D-K-A-Q-S-M-K-R-F-S-A-R-A-K-G-R-G-N-R-I-E-K-Q-T-C-H-I-T-V-K-V-G-A"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-I-K-K-G-P-F-V-D-A-H-L-I-K-K-V-D-A-A-V-A-G-K-D-K-K-P-I-K-T-W-S-R-R-S-T-V-L-P-E-F-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-Y-I-N-E-N-M-V-G-H-K-L-G-E-F-A-L-T-R-T-F-K-G-H-A-A-D-K-K-S-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-A-E-R-L-M-Q-V-I-L-A-P-I-V-T-E-K-A-T-F-V-A-E-K-N-Q-Q-V-A-F-R-V-V-A-D-A-T-K-P-E-I-K-A-A-V-E-L-L-F-K-V-Q-V-E-S-V-Q-V-L-N-R-K-G-K-V-K-R-F-G-R-F-V-G-R-R-R-N-E-R-K-A-Y-V-A-L-K-D-G-Q-E-I-D-F-A-E-V-K"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-N-Q-K-I-R-I-R-L-K-A-F-D-Y-K-L-I-D-Q-S-A-A-E-I-V-D-T-A-K-R-T-G-A-V-V-R-G-P-V-P-L-P-T-R-I-R-R-Y-D-V-L-R-S-P-H-V-N-K-T-S-R-D-Q-F-E-I-R-T-H-Q-R-L-M-D-I-V-D-P-T-D-K-T-V-D-A-L-M-R-L-D-L-P-A-G-V-D-V-E-I-A-L-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-E-V-P-K-R-E-I-L-P-D-P-K-F-G-S-V-E-L-A-K-F-M-N-V-V-M-L-D-G-K-K-A-V-A-E-R-I-I-Y-G-A-L-E-Q-V-Q-V-K-T-G-K-D-A-I-E-V-F-N-L-A-I-N-N-I-K-P-I-V-E-V-K-S-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-R-P-V-R-R-L-A-L-A-M-R-W-L-R-E-A-A-K-K-R-G-E-K-S-M-D-L-R-L-A-G-E-L-I-D-A-S-E-G-R-G-A-A-M-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-S-H-F-R-W"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-S-K-A-E-I-L-D-A-I-A-G-M-S-V-L-E-L-S-E-L-I-K-E-M-E-E-K-F-G-V-S-A-A-A-A-A-V-A-V-A-A-P-A-A-G-G-A-G-A-A-A-A-E-E-Q-T-E-F-T-V-V-L-L-E-A-G-A-N-K-V-S-V-I-K-A-V-R-E-L-T-G-L-G-L-K-E-A-K-D-L-V-D-G-A-P-K-P-V-K-E-A-L-P-K-A-D-A-E-A-A-K-K-K-L-E-E-A-G-A-K-V-E-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-L-N-R-Q-E-K-A-V-V-I-E-E-V-S-A-Q-V-A-K-A-Q-S-I-V-I-A-E-Y-R-G-L-D-V-A-S-V-T-V-L-R-K-T-A-R-E-S-G-V-Y-L-R-V-L-K-N-T-L-V-R-R-A-V-A-G-T-A-F-E-P-L-S-E-Q-L-T-G-P-L-I-Y-G-I-S-A-D-P-V-A-A-A-K-V-L-A-G-F-A-K-S-N-D-K-L-V-I-K-A-G-S-L-P-N-S-L-L-T-Q-D-G-V-K-A-L-A-T-M-P-S-R-E-E-L-L-S-K-L-L-G-T-M-Q-A-P-I-A-Q-F-V-R-T-L-N-E-V-P-T-K-F-A-R-G-L-A-A-V-R-D-Q-K-A-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-V-G-F-I-K-L-Q-V-P-A-G-K-A-N-P-S-P-P-I-G-P-A-L-G-Q-R-G-L-N-I-M-E-F-C-K-A-F-N-A-K-T-Q-G-M-E-P-G-L-P-I-P-V-V-I-T-A-F-A-D-K-S-F-T-F-I-M-K-T-P-P-A-T-V-L-I-K-K-A-S-G-V-Q-K-G-S-A-K-P-H-T-D-K-V-G-T-L-T-R-A-Q-A-E-E-I-A-K-T-K-Q-P-D-L-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-I-T-V-E-G-V"} +{"text": "### FUNCTION Channel that permits osmotically driven movement of water in both directions It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells It mediates rapid entry or exit of water in response to abrupt changes in osmolarity ### SEQUENCE -M-K-K-L-F-A-E-F-F-G-T-Y-W-L-V-F-G-G-C-G-S-A-V-F-A-A-G-Y-P-T-L-G-I-G-F-A-G-V-A-L-A-F-G-L-T-V-L-T-M-A-Y-A-V-G-H-I-S-G-G-H-F-N-P-A-V-S-F-G-L-W-A-G-G-R-F-S-A-K-D"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-F-K-E-Y-K-I-Y-K-F-F-E-Q-V-K-Q-E-T-Y-K-V-V-W-P-T-R-K-E-L-V-A-S-T-L-V-V-V-V-A-V-F-I-F-S-L-I-C-L-V-L-D-Y-S-I-H-N-I-M-Q-L-L-L-N-I-G-K"} +{"text": "### FUNCTION Involved in spore germination ### SEQUENCE -M-F-E-W-N-K-Y-F-P-F-H-N-Q-F-S-K-E-A-L-K-K-A-D-P-K-E-V-E-T-Y-V-N-R-V-M-E-S-V-F-G-S-D-Y-A-A-Q-F-P-F-R-D-P-L-P-Q-K-E-H-P-A-K-P-D-A-K-P-D-V-K-P-D-I-D-I-F-E-T-A-D-H-V-F-V-K-V-P-I-S-E-E-W-L-E-Q-V-R-I-K-H-T-S-H-E-L-W-L-E-N-L-P-R-A-D-H-P-K-K-V-N-L-P-C-L-V-K-R-K-G-T-K-A-V-Y-K-D-G-L-L-E-V-M-F-Q-K-Q-Q-D-Y-N-M-S-E-V-E-I-I-R"} +{"text": "### FUNCTION May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor ### SEQUENCE -M-I-K-Y-L-S-T-N-I-S-L-Y-F-Q-E-N-N-S-C-L-S-K-K-D-V-L-K-I-Q-Y-T-L-E-A-I-L-S-D-L-S-K-F-I-I-I-F-L-V-F-L-F-I-K-E-I-P-L-F-L-F-S-F-I-I-L-N-S-T-R-P-L-L-G-G-I-H-C-K-T-Y-Y-G-C-L-T-C-S-I-L-Y-F-M-I-I-L-L-F-T-R-L-F-P-E-L-N-T-N-F-Y-I-V-F-F-I-L-S-L-A-I-T-F-I-F-A-P-C-P-N-E-K-R-P-V-K-N-K-A-T-L-K-I-L-S-L-I-S-L-T-F-W-I-I-L-F-Y-L-S-P-L-Q-T-R-N-C-I-L-I-S-I-F-L-Q-I-I-Q-V-I-I-I-N-T-K-G-V-I-F-N-A-K-N-N-K-T-F-F-N-R-T-T"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-A-V-N-Q-I-G-N-R-F-D-M-I-L-V-A-A-R-R-A-R-Q-I-A-V-Q-G-K-D-P-M-V-E-E-E-N-D-K-P-T-V-I-A-L-R-E-I-E-L-G-L-V-T-A-D-T-L-D-A-D-E-R-Q-T-V-R-E-R-E-A-A-E-I-A-A-V-A-A-I-A-E-G-R-N-D-I-L"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-R-P-R-P-A-T-F-D-K-V-K-T-V-A-E-N-R-R-A-R-F-D-Y-F-I-E-Q-T-Y-E-A-G-L-V-L-T-G-T-E-V-K-S-L-R-F-G-E-G-S-I-A-E-A-Y-A-E-V-K-D-E-X-V-W-L-V-N-A-N-I-P-E-F-S-H-G-N-R-F-N-H-E-A-K-R-P-R-K-L-L-L-H-E-R-E-I-N-K-L-H-G-A-V-A-R-E-G-M-T-L-V-P-L-S-V-Y-F-N-G-K-G-R-A-K-V-E-L-A-L-A-K-G-K-K-T-H-D-K-R-E-T-I-K-E-R-D-W-K-R-E-Q-S-R-I-L-R-D-R-G"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-D-E-K-D-L-A-T-Q-P-E-E-A-G-Q-D-P-R-L-P-G-P-H-E-D-P-R-R-Q-E-G-V-E-A-E-K-A-E-G-P-L-A-P-H-P-Q-G-E-R-L-S-Q-P-P-P-A-A-G-G-K-L-L-S-L-K-G-D-R-A-F-Q-R-L-R-Q-G-R-M-G-R-G-R-F-L-N-V-K-W-L-P-A-S-E-L-R-V-G-I-V-V-S-K-K-V-G-K-A-V-V-R-N-R-I-K-R-R-L-R-E-I-L-R-R-L-H-L-P-K-A-H-L-L-V-I-A-S-P-E-A-R-E-A-T-Y-A-E-L-F-Q-D-L-I-R-A-L-K-K-S-G-L-I-Q"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-D-E-K-D-L-A-T-Q-P-Q-E-T-G-Q-D-P-R-L-P-G-Q-D-A-H-P-R-G-A-Q-G-A-E-A-Q-A-A-E-G-P-L-A-A-H-A-Q-G-A-P-L-K-S-L-K-G-D-S-A-F-R-R-L-R-Q-G-R-T-G-R-G-R-Y-V-T-V-R-W-L-P-A-P-E-L-R-V-G-I-V-V-S-K-K-V-G-K-T-V-V-R-N-R-V-K-R-R-L-R-E-I-L-R-R-L-H-L-P-R-A-H-L-L-L-V-A-T-P-E-A-R-E-A-G-F-A-E-L-F-Q-D-L-T-R-A-L-K-K-S-G-L-V-Q"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-D-E-K-D-L-A-T-Q-P-E-E-A-G-Q-D-P-R-L-P-G-P-H-E-D-P-R-R-Q-E-R-A-E-A-Q-A-K-K-G-P-L-A-P-D-A-Q-G-K-R-L-G-Q-G-P-P-K-A-G-G-R-L-L-S-L-K-G-D-R-A-F-Q-R-L-R-K-G-R-A-G-R-G-R-F-V-S-V-K-W-L-P-A-P-E-A-R-V-G-I-V-V-S-K-K-V-G-K-A-V-V-R-N-K-V-K-R-R-L-R-E-I-L-R-R-L-H-L-P-K-A-H-I-L-L-V-A-S-P-E-A-R-E-A-G-F-A-E-L-F-Q-D-V-V-R-A-L-R-K-S-G-L-I-Q"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-D-E-K-D-L-A-A-Q-P-E-E-A-G-Q-D-P-R-L-P-G-P-H-E-D-P-R-R-Q-E-G-A-E-A-Q-A-A-E-G-P-L-A-P-H-A-Q-G-E-R-L-K-R-P-P-P-A-P-G-G-K-L-V-S-L-K-G-D-R-A-F-Q-R-L-R-K-G-K-A-G-R-G-R-Y-V-S-V-K-W-L-P-A-P-E-L-R-V-G-I-V-V-S-K-K-V-G-K-A-V-V-R-N-K-V-K-R-R-L-R-E-I-L-R-R-L-H-L-P-K-A-H-L-L-V-V-A-S-P-E-A-R-E-A-S-Y-V-E-L-F-Q-D-V-A-R-A-L-K-K-S-G-L-I-Q"} +{"text": "### FUNCTION Seed storage protein ### SEQUENCE -M-A-S-A-S-D-K-L-V-L-S-A-I-V-L-A-V-L-A-A-V-V-A-A-A-S-G-Y-G-D-V-G-E-Y-C-R-V-G-K-A-V-S-R-N-P-V-P-S-C-R-N-Y-I-A-R-W-C-A-A-A-G-G-R-M-D-S-R-K-Q-P-P-R-E-F-L-E-P-C-C-R-E-L-A-A-V-P-M-Q-C-R-C-D-A-L-S-V-L-V-R-G-V-V-T-E-E-G-D-R-V-S-G-M-I-S-Q-H-A-A-P-G-C-D-A-A-T-I-A-G-M-A-S-A-L-T-D-Y-G-R-C-N-L-Q-H-T-A-G-S-F-A-C-L-M-F-G-G-G-M-D"} +{"text": "### FUNCTION Seed storage protein ### SEQUENCE -M-A-L-A-S-D-K-F-V-L-S-A-I-V-L-A-V-L-T-V-A-A-A-A-A-G-Y-G-G-Y-G-D-V-G-E-Y-C-R-V-G-K-A-V-S-R-N-P-V-P-S-C-R-N-Y-I-A-R-W-C-A-V-A-G-G-R-L-D-S-G-K-Q-P-P-R-Q-L-L-E-P-C-C-R-E-L-A-A-V-P-M-Q-C-R-C-D-A-L-S-V-L-V-R-G-V-V-T-E-E-G-D-R-V-A-G-M-I-S-Q-H-A-A-P-G-C-D-A-A-T-I-A-G-M-A-S-A-L-T-D-Y-G-R-C-N-L-Q-H-T-G-F-F-G-C-P-M-F-G-G-G-M-D"} +{"text": "### FUNCTION Repressor of jasmonate responses ### SEQUENCE -M-A-A-E-A-A-A-T-S-R-F-A-A-A-C-G-A-L-S-Q-Y-V-R-A-A-D-N-V-H-R-A-R-T-A-A-A-A-A-A-V-R-P-L-P-L-M-P-G-A-D-V-A-G-D-E-R-E-E-E-G-G-G-A-A-A-S-S-A-A-A-Q-M-T-I-F-Y-G-G-R-V-L-V-L-D-E-C-P-A-D-R-A-A-A-L-L-R-L-A-A-S-S-R-G-V-P-R-D-D-L-A-S-T-A-A-A-A-G-E-S-A-D-L-P-V-A-R-K-A-S-L-Q-R-F-M-E-K-R-K-G-R-L-A-A-R-G-Q-P-Y-R-R-H-D-A-A-A-A-A-R-G-D-H-L-A-L-A-L"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-E-G-E-Q-Q-Q-Q-Q-Q-Q-S-V-A-A-V-R-P-S-L-G-K-A-P-S-P-S-F-R-L-R-N-G-S-L-N-A-V-R-L-R-R-V-F-D-L-F-D-R-N-G-D-G-E-I-T-V-D-E-L-A-Q-A-L-D-A-L-G-L-E-A-D-R-A-G-L-A-A-T-V-G-A-H-V-P-D-G-A-A-G-L-R-F-E-D-F-E-S-L-H-R-A-L-G-D-A-L-F-G-S-L-D-V-P-E-D-G-G-G-G-G-G-G-D-E-E-M-K-E-A-F-K-V-F-D-V-D-G-D-G-F-I-S-A-S-E-L-Q-E-V-L-K-K-L-G-M-P-E-A-G-S-L-A-N-V-R-E-M-I-C-N-V-D-R-D-S-D-G-R-V-D-F-G-E-F-K-C-M-M-Q-G-I-T-V-F-G-A"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-S-E-R-V-F-A-E-L-A-T-I-H-Y-Q-K-S-L-P-C-R-H-S-F-D-P-P-R-T-T-P-I-L-H-L-Y-I-I-H-L-L-L-P-P-L-I-A-I-V-C-L-C-Y-I-A-I-V-P-F-E-E-E-E-E-R-M-R-M-Q-V-V-E-T-A-A-V-E-E-E-E-A-A-A-A-M-M-S-V-Y-E-R-V-A-R-M-A-S-G-N-A-V-V-V-F-S-A-S-G-C-C-M-C-H-V-V-K-R-L-L-L-G-L-G-V-G-P-A-V-Y-E-L-D-Q-L-A-A-A-A-D-I-Q-A-A-L-S-Q-L-L-P-P-G-Q-P-P-V-P-V-V-F-V-G-G-R-L-L-G-G-V-E-K-V-M-A-C-H-I-N-G-T-L-V-P-L-L-K-Q-A-G-A-L-W-L"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-A-R-A-Q-L-V-L-V-A-L-V-A-A-A-L-L-L-A-G-P-H-T-T-M-A-A-I-S-C-G-Q-V-N-S-A-V-S-P-C-L-S-Y-A-R-G-G-S-G-P-S-A-A-C-C-S-G-V-R-S-L-N-S-A-A-S-T-T-A-D-R-R-T-A-C-N-C-L-K-N-V-A-G-S-I-S-G-L-N-A-G-N-A-A-S-I-P-S-K-C-G-V-S-I-P-Y-T-I-S-P-S-I-D-C-S-S-V-N"} +{"text": "### FUNCTION Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space ### SEQUENCE -M-G-Q-G-L-S-Q-P-A-Q-A-V-E-E-P-S-P-P-A-V-E-A-A-P-S-S-S-P-S-P-A-P-A-P-S-S-L-E-A-L-A-A-E-A-M-S-F-D-E-D-G-N-E-S-I-D-V-K-V-Q-K-A-L-D-C-P-C-V-A-E-L-K-N-G-P-C-G-S-Q-F-V-D-A-F-S-C-F-L-K-S-T-E-E-E-K-G-S-D-C-V-K-P-F-I-A-L-Q-D-C-I-K-I-N-P-E-A-F-S-K-E-I-L-E-E-E-E-N-D-E-E-A-E-K-S-N-L-K-V-R-A-P-A-W-S-R-E-S-K-P-K-L"} +{"text": "### FUNCTION DNA-binding protein that specifically recognizes a negative element within the RPS1 promoter ### SEQUENCE -M-A-D-Q-F-A-D-S-A-N-N-V-V-I-E-E-V-N-K-G-L-N-P-G-M-I-V-L-I-V-V-A-T-F-L-L-L-F-F-V-G-N-Y-A-L-Y-V-Y-A-Q-K-T-L-P-P-R-K-K-K-P-V-S-K-K-K-M-K-R-E-K-L-K-Q-G-V-S-A-P-G-E"} +{"text": "### FUNCTION Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes May directly activate some type-A response regulators in response to cytokinins ### SEQUENCE -M-A-F-Q-T-Q-G-S-N-L-R-A-L-L-V-E-D-I-K-V-N-R-M-I-L-S-Q-M-L-R-K-F-Q-V-E-T-T-V-V-Q-N-G-K-E-A-V-E-L-F-L-G-G-E-T-F-D-I-V-L-T-D-N-L-M-P-I-M-T-G-P-E-A-I-S-K-I-R-A-M-G-A-T-D-V-M-I-V-G-V-S-V-D-A-N-S-M-E-E-F-K-D-A-G-A-D-L-C-V-P-K-L-K-L-E-I-L-E-H-I-L-Q-E-T-R-S-K-K-N-K-S-S-A"} +{"text": "### FUNCTION Acts in maintaining the cortical microtubules organization essential for anisotropic cell growth ### SEQUENCE -M-S-R-A-C-R-G-E-S-S-G-G-G-R-S-S-L-G-Y-L-F-E-P-E-P-E-D-I-I-P-D-H-S-T-K-S-V-Q-G-T-N-K-A-P-K-G-N-I-V-L-G-D-K-M-A-S-D-E-A-D-Q-E-H-Q-A-A-A-P-L-K-K-E-D-S-N-P-I-V-S-S-R-S-A-S-N-I-Y-H-T-N-Q-V-G-N-N-S-G-L-L-I-T-D-R-P-S-T-R-V-R-C-A-P-G-G-P-S-S-L-G-F-L-F-G-D-E-D-A"} +{"text": "### FUNCTION May serve as docking site to facilitate the association of other proteins to the plasma membrane ### SEQUENCE -M-A-E-K-E-E-G-K-V-A-A-E-G-G-A-E-A-E-A-D-E-E-V-E-V-K-F-R-L-F-D-G-S-D-I-G-P-L-R-C-N-A-V-A-T-T-V-A-A-L-K-D-R-V-V-A-D-W-P-K-D-K-T-I-V-P-K-T-A-N-D-V-K-L-I-S-G-G-K-I-L-E-N-D-K-N-I-A-Q-C-R-A-P-F-G-D-L-P-S-T-A-I-T-M-H-V-V-V-Q-P-S-S-A-K-S-K-P-D-K-K-T-N-K-L-P-K-T-T-R-C-S-C-T-I-L"} +{"text": "### FUNCTION Actin-depolymerizing protein Severs actin filaments ### SEQUENCE -M-A-N-S-A-S-G-M-A-V-G-D-E-C-K-L-K-F-Q-E-L-K-S-K-R-S-F-R-F-I-T-F-K-I-D-E-R-T-Q-Q-V-V-V-D-R-L-G-Q-P-G-D-T-Y-D-D-F-T-A-S-M-P-A-S-E-C-R-Y-A-V-F-D-F-D-F-V-T-D-E-N-C-Q-K-S-K-I-F-F-I-S-W-S-P-D-T-S-K-V-R-S-K-M-L-Y-A-S-S-K-D-R-F-K-R-E-L-D-G-I-Q-V-E-L-Q-A-T-D-P-S-E-M-S-M-D-I-V-K-A-R-A-L"} +{"text": "### FUNCTION Involved in the transport of copper ### SEQUENCE -M-R-G-M-G-D-D-G-M-G-P-M-A-M-A-P-P-R-S-G-H-A-T-A-A-A-P-P-P-P-Q-H-K-M-A-M-M-M-H-M-T-F-F-W-S-D-R-A-V-V-L-I-R-G-W-P-G-E-R-G-A-G-M-Y-A-L-C-L-L-F-V-L-A-L-A-A-L-T-E-G-L-S-V-L-S-R-R-L-A-R-R-G-G-G-A-A-S-S-D-G-G-R-P-A-P-A-P-A-S-S-A-A-L-L-T-A-V-H-A-A-R-M-G-M-A-Y-L-V-M-L-A-V-M-S-F-N-V-G-V-L-L-A-A-V-A-G-H-A-L-G-F-L-L-A-R-S-R-V-R-P-A-A-R-D-G-G-G-G-V-A-C-E-H-G-G-L-P-P-A-D-G-S-K-T"} +{"text": "### FUNCTION Regulates membrane-cell wall junctions and localized cell wall deposition Required for establishment of the Casparian strip membrane domain ### SEQUENCE -M-E-H-G-E-I-S-S-K-A-P-L-V-A-P-V-A-A-G-V-N-R-A-V-A-V-V-D-T-F-L-R-F-I-A-I-I-G-T-I-G-S-A-I-A-M-G-T-T-N-E-T-L-P-F-F-T-Q-F-I-Q-F-E-A-K-Y-S-D-L-P-S-F-T-F-F-V-A-A-N-A-V-V-C-T-Y-L-V-L-S-I-P-L-S-I-V-H-I-L-R-P-R-A-R-Y-S-R-L-F-L-V-F-F-D-T-A-M-L-A-L-L-T-A-G-A-S-A-A-A-A-I-V-Y-L-A-H-K-G-N-V-R-A-N-W-F-S-I-C-Q-Q-F-D-S-F-C-E-R-I-S-G-S-L-I-G-S-F-A-A-M-V-L-L-V-V-L-I-T-L-S-A-F-A-L-A-R-R-H"} +{"text": "### FUNCTION Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca complex are a number of protein kinases and phosphatases ### SEQUENCE -M-A-D-Q-L-T-D-D-Q-I-S-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-C-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-Q-D-M-I-N-E-V-D-A-D-G-N-G-T-I-D-F-P-E-F-L-N-L-M-A-R-K-M-K-D-T-D-S-E-E-E-L-K-E-A-F-R-V-F-D-K-D-Q-N-G-F-I-S-A-A-E-L-R-H-V-M-T-N-L-G-E-K-L-T-D-E-E-V-D-E-M-I-R-E-A-D-V-D-G-D-G-Q-I-N-Y-E-E-F-V-K-V-M-M-A-K"} +{"text": "### FUNCTION Acts in maintaining the cortical microtubules organization essential for anisotropic cell growth ### SEQUENCE -M-S-R-G-G-S-A-G-G-G-Q-S-S-L-G-Y-L-F-G-G-N-E-A-P-K-P-A-A-K-P-A-P-A-A-A-P-A-P-A-P-A-P-A-P-A-A-A-V-A-A-P-A-E-K-P-S-P-A-K-A-D-A-T-K-Q-I-P-A-G-I-Q-G-S-R-S-N-N-N-Y-H-R-A-D-G-Q-N-T-G-N-F-L-T-D-R-P-S-T-K-V-H-A-A-P-G-G-G-S-S-L-G-Y-L-F-G-G-N"} +{"text": "### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-A-Q-E-S-W-K-N-E-S-E-E-T-V-H-T-P-E-A-P-I-L-C-V-N-N-C-G-F-F-G-S-S-M-T-N-N-M-C-S-K-C-Y-R-D-F-V-K-V-T-T-M-A-A-P-V-V-E-K-K-A-F-T-P-A-S-S-S-K-T-P-L-E-P-A-K-P-D-E-V-P-A-A-A-V-E-D-K-Q-A-A-Q-E-P-P-K-P-P-S-N-R-C-L-S-C-R-K-K-V-G-L-T-G-F-Q-C-R-C-G-G-T-F-C-S-T-H-R-Y-T-E-A-H-D-C-T-F-D-Y-K-K-A-G-R-D-Q-I-A-K-Q-N-P-V-V-I-A-E-K-I-N-K-I"} +{"text": "### FUNCTION Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans Host outer membrane disruption is possibly due to local fusion between the inner and outer membrane performed by the spanin complex ### SEQUENCE -M-P-R-T-I-V-A-I-L-V-L-A-V-V-A-L-G-A-S-Y-G-F-V-Q-S-Y-R-A-L-G-I-A-Q-G-E-I-K-R-Q-T-A-R-A-E-A-L-E-V-R-Y-A-T-L-Q-R-H-V-K-E-V-A-A-R-T-N-T-Q-R-Q-E-V-D-R-A-L-D-Q-N-R-P-W-A-D-R-P-V-P-A-A-V-V-D-S-L-C-N-R-P-G-A-R-C-A-V-R-T-P-T-D"} +{"text": "### FUNCTION Capsid decoration protein which helps to stabilize the capsid against extremes of pH and temperature Once maturation and expansion of the capsid has occured, trimers of soc attach the interfaces between the hexamer of the major capsid protein Acts as a 'glue' between neighboring hexameric capsomers Dispensable for the head morphogenesis and phage infection ### SEQUENCE -M-G-G-Y-V-N-I-K-T-F-T-H-P-A-G-E-G-K-E-V-K-G-M-E-V-S-V-P-F-E-I-Y-S-N-E-H-R-I-A-D-A-H-Y-Q-T-F-P-S-E-K-A-A-Y-T-T-V-V-T-D-A-A-D-W-R-T-K-N-A-A-M-F-T-P-T-P-V-S-G"} +{"text": "### FUNCTION Forms the collar, into which the side tail fiber protein pb1 is anchored ### SEQUENCE -M-S-T-E-N-R-V-I-D-L-V-V-D-E-N-V-P-Y-G-L-L-M-Q-F-M-D-V-D-D-S-V-Y-P-S-T-S-K-P-V-D-L-T-D-F-S-L-R-G-S-I-K-S-S-L-E-D-G-A-E-T-V-A-S-F-T-T-A-I-V-D-A-A-Q-G-V-A-S-I-S-L-P-V-S-A-V-T-T-I-A-S-K-A-S-K-E-R-D-R-Y-N-P-R-Q-R-L-A-G-Y-Y-D-V-I-I-T-R-T-A-V-G-S-A-A-S-S-F-R-I-M-E-G-K-V-Y-I-S-D-G-V-T-Q"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-I-K-Q-L-I-R-N-T-R-Q-P-I-R-N-V-T-K-S-P-A-L-R-G-C-P-Q-R-R-G-T-C-T-R-V-Y-T-I-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-I-T-A-Y-I-P-G-I-G-H-N-S-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-A-V-G-V-K-D-R-Q-Q-G-R-S-K-Y-G-V-K-K-P-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-V-P-T-A-F-L-L-I-I-Y-V-K-T-E-S-Q-N-K-K"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-D-G-I-K-Y-A-V-F-T-E-K-S-I-R-L-L-G-N-N-Q-Y-T-S-N-V-E-S-G-S-T-R-T-E-I-K-H-W-V-E-L-F-F-G-V-K-V-I-A-M-N-S-H-R-L-P-G-K-G-R-R-M-G-H-T-M-H-Y-R-R-M-I-I-T-L-Q-P-G-Y-S-I-P-P-L-I-E-K-R-T"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-L-K-K-N-P-F-V-A-N-H-L-L-A-K-I-E-K-L-N-M-R-E-E-K-E-T-I-V-T-W-S-R-A-S-T-I-I-P-T-M-I-G-H-T-I-A-I-H-N-G-K-E-H-L-P-I-F-I-T-D-R-M-V-G-H-K-L-G-E-F-A-P-T-L-T-F-R-G-H-A-R-T-D-T-R-S-R-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-S-K-K-K-Q-K-M-K-R-S-S-S-T-Q-V-Q-A-L-A-Q-H-I-S-M-S-A-H-K-A-R-R-V-V-D-Q-I-R-G-R-S-Y-A-E-T-L-M-L-L-E-L-M-P-Y-R-A-S-Y-P-I-F-K-L-V-Y-S-A-A-A-N-A-S-H-N-K-S-F-N-E-A-D-S-F-I-S-K-A-E-V-N-G-G-T-I-V-K-K-F-K-P-R-A-K-G-R-S-Y-P-I-K-R-P-T-C-H-I-T-I-V-L-K-D-R-S-K-K-K-T-D-Q-D-M-F-L-G-T-K-N-V"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-P-Q-T-H-L-N-V-A-D-N-S-G-A-R-E-L-M-C-I-R-I-I-G-A-S-N-R-R-Y-A-H-I-G-D-V-I-V-A-V-I-K-E-A-V-P-N-M-P-L-E-R-S-E-V-I-R-A-V-I-V-R-T-C-K-E-L-K-R-D-N-G-M-I-I-R-Y-D-D-N-A-A-V-V-I-D-Q-E-G-N-P-K-G-T-R-V-F-G-A-I-A-R-E-L-R-K-L-N-F-T-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-R-D-T-I-A-D-I-L-T-S-I-R-N-A-N-M-D-K-K-G-T-V-R-I-A-S-T-N-I-T-E-N-I-V-K-I-L-L-R-E-G-F-I-E-N-V-R-K-H-Q-E-N-N-K-Y-F-L-V-S-T-L-Q-H-R-R-N-R-K-G-R-Y-R-T-I-L-K-R-I-S-R-P-G-L-R-I-Y-S-N-Y-Q-R-I-P-R-I-L-G-G-M-G-I-V-I-L-S-T-S-Q-G-I-M-T-D-R-E-A-R-L-E-G-I-G-G-E-I-L-C-Y-I-W"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-L-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-L-I-L-G-Y-V-S-G-R-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-V-S-S-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-N-D"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-G-V-T-K-K-P-D-L-N-D-P-V-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-S-P-V-V-I-L-G-T-I-A-C-N-V-G-L-A-V-L-E-P-S-M-I-G-E-P-A-D-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-F-P-V-F-Q-I-L-R-T-V-P-N-K-L-L-G-V-L-L-M-V-L-V-P-T-G-L-L-T-V-P-F-L-E-N-V-N-K-F-Q-N-P-F-R-R-P-V-A-T-T-V-F-L-I-G-T-A-V-A-L-W-L-G-I-G-A-T-L-P-I-D-K-S-L-T-L-G-L-F-Q-V-D-L-T-V-K"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-M-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-I-R-R-G-Y-I-A-R-R-R-R-T-K-I-R-L-F-A-S-T-F-R-G-A-H-S-R-L-T-R-T-I-T-Q-Q-K-M-R-A-L-V-S-T-Q-R-D-R-G-R-R-K-R-D-F-R-R-L-W-I-T-R-I-N-A-V-T-R-E-N-R-V-S-Y-S-Y-S-R-L-I-H-D-L-Y-K-K-R-L-L-L-N-R-K-I-L-A-Q-I-A-I-S-N-R-N-C-L-D-T-I-S-N-E-I-L-K"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-R-D-I-K-T-Y-L-S-T-A-P-V-L-A-T-L-W-F-G-S-L-A-G-L-L-I-E-I-N-R-L-F-P-D-A-L-T-F-P-F-F-S-F"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex ### SEQUENCE -M-P-T-I-T-S-Y-F-G-F-L-L-A-A-S-T-I-T-P-A-L-L-I-G-L-N-K-I-R-L-I"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-D-T-T-G-R-I-P-L-W-L-I-G-T-V-T-G-I-P-V-I-G-S-I-G-I-F-F-Y-G-S-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-N-W-R-S-E-R-I-W-I-E-L-I-T-G-S-R-K-T-S-N-F-C-W-A-C-I-L-F-L-G-S-L-G-F-L-L-V-G-T-S-S-Y-L-G-R-N-L-I-S-L-F-P-S-Q-Q-I-I-F-F-P-Q-G-I-V-M-S-F-Y-G-I-A-G-L-F-I-S-S-Y-L-W-C-T-I-S-W-N-V-G-S-G-Y-D-R-F-D-R-K-E-G-I-V-C-I-F-R-W-G-F-P-G-I-N-R-R-I-F-L-R-F-L-M-R-D-I-Q-S-I-R-M-E-V-K-G-G-L-Y-S-R-R-V-L-Y-M-E-I-R-G-Q-G-A-I-P-L-T-R-T-D-E-N-F-T-P-R-E-I-E-Q-K-A-A-E-L-A-Y-F-L-R-V-P-I-E-L-K"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-T-D-L-N-L-P-S-I-F-V-P-L-V-G-L-M-F-P-A-I-A-M-A-S-L-S-L-H-I-Q-K-N-K-I-I"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-T-L-N-L-C-V-L-T-P-N-R-I-I-W-D-S-E-V-K-E-I-I-L-S-T-N-S-G-Q-I-G-V-L-P-N-H-A-P-I-A-T-A-V-D-I-G-I-L-R-I-R-L-N-G-Q-W-L-M-M-A-V-M-G-G-F-A-R-I-G-N-N-E-I-T-I-L-V-N-D-A-E-K-G-S-D-I-D-P-Q-E-A-Q-R-T-L-E-I-A-E-A-N-L-S-K-A-E-G-K-R-Q-V-I-E-A-N-L-A-L-R-R-A-R-T-R-V-E-A-I-N-V-I"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-R-I-N-G-N-F-I-D-K-T-S-S-I-V-A-N-I-L-L-R-I-I-P-T-T-S-G-E-K-E-A-F-T-Y-Y-R-D-G-M-S-A-Q-S-E-G-N-Y-A-E-A-L-Q-N-Y-Y-E-A-T-R-L-E-I-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-E-H-T-K-A-L-E-Y-Y-F-R-A-I-E-R-N-P-F-L-P-Q-A-F-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-R-Q-G-D-S-E-I-A-E-A-W-S-D-Q-A-A-E-Y-W-K-Q-A-I-A-L-T-P-G-N-Y-I-E-A-H-N-W-L-K-I-A-R-R-F-E"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-R-K-G-L-I-Q-R-E-R-K-R-Q-K-L-E-Q-K-Y-H-L-I-R-R-S-P-K-K-E-I-G-K-V-S-S-L-S-D-K-W-K-I-H-G-K-L-Q-S-P-P-R-N-S-A-P-T-R-L-H-R-R-C-F-L-T-G-R-P-R-A-N-Y-R-D-F-G-L-S-G-H-I-L-R-E-K-V-H-A-C-L-L-P-G-A-T-R-S-S-W"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -M-I-I-A-F-Q-L-A-V-F-A-L-I-A-T-S-S-I-L-L-I-S-V-P-V-V-F-A-S-P-D-G-W-S-N-N-K-N-V-V-F-S-G-T-S-L-W-I-G-L-V-F-L-V-A-I-L-N-S-L-I-S"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-N-V-T-D-S-F-V-S-L-G-H-W-P-F-A-G-S-F-G-F-N-T-D-I-L-A-T-N-L-I-N-L-S-V-V-L-G-V-L-I-F-F-G-K-G-V-L-S-D-L-L-D-N-R-K-Q-R-I-W-S-T-I-R-N-S-D-E-L-R-E-V-A-I-E-Q-L-E-K-A-R-A-R-L-R-K-V-E-R-E-A-D-E-F-R-V-N-G-Y-S-E-I-E-R-E-K-W-N-L-I-N-A-T-Y-E-N-L-E-R-L-E-N-Y-K-N-E-T-I-H-F-E-Q-Q-R-A-I-N-Q-V-R-Q-R-V-F-Q-Q-A-L-Q-G-A-L-G-T-L-N-S-R-S-N-S-E-L-H-L-R-T-I-S-A-N-I-G-M-L-G-A-M-K-E-I-T-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-N-I-F-S-L-I-C-L-N-S-A-L-H-S-S-S-F-F-F-A-K-L-P-E-A-Y-A-F-F-N-P-I-V-D-V-M-P-V-I-P-V-L-F-F-L-L-A-L-V-W-Q-A-A-V-S-F-R"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-C-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-K-E-L-R-D-P-F-E-E-H-E-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-C-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-K-E-L-R-D-P-F-E-E-H-E-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-I-A-I-F-I-S-C-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-K-E-L-R-D-P-F-E-E-H-E-D"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-L-T-F-N-Q-L-I-K-N-S-R-K-K-K-N-K-F-K-N-S-I-L-N-R-C-P-Q-K-K-G-I-C-L-K-V-F-T-K-S-P-K-K-P-N-S-A-L-R-K-V-V-K-I-R-L-S-N-N-K-E-I-I-A-Y-I-P-G-E-G-Y-A-I-Q-E-H-N-Y-A-L-I-K-G-G-K-V-Q-D-L-P-G-I-R-Y-K-I-I-R-G-A-L-N-V-S-G-V-K-N-R-K-S-S-R-S-K-Y-G-T-K-K"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-T-Q-I-N-T-Y-F-N-I-A-D-N-S-G-V-K-K-I-L-C-I-Q-N-L-T-K-K-T-K-K-I-E-I-G-D-L-I-V-G-V-I-K-K-I-N-N-T-S-K-L-I-Y-S-N-I-V-Y-G-I-V-I-R-L-K-K-N-I-N-L-Y-K-K-Y-N-I-S-F-N-D-N-S-A-V-L-V-D-K-N-L-N-P-I-G-S-R-I-F-G-T-I-P-K-F-L-K-K-K-N-Y-L-K-L-Y-S-L-T-V-D-F-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-L-R-Y-L-G-P-K-L-K-K-L-K-R-L-N-I-H-M-Q-P-E-F-S-T-K-Y-F-I-L-N-T-N-K-Y-N-N-K-M-I-L-S-F-Y-L-L-E-L-F-E-K-Q-K-L-K-F-T-F-S-L-S-E-K-I-I-K-K-Y-I-L-F-M-H-K-Y-N-Y-K-K-F-N-L-I-N-I-I-E-I-R-L-D-N-T-I-F-N-L-G-Y-S-I-T-I-A-Q-A-K-Q-L-I-I-H-G-Y-F-F-V-N-F-K-L-I-K-I-P-S-F-L-L-K-K-G-D-I-I-T-L-S-P-K-S-Y-Y-I-F-K-L-C-K-K-N-L-Y-K-K-Y-I-K-N-S-N-I-Y-D-T-I-Y-I-C-K-N-T-L-I-S-I-I-Y-S-I-L-N-I-Y-N-N-N-N-Y-N-N-I-L-I-M-K-Y-Y-S-Y"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-I-Q-T-K-K-I-K"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-I-Q-T-K-K-M-K"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-I-Q-T-K-K-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-I-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-I-Q-T-K-K-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-I-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-I-Q-T-K-K-M-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-V-P-T-A-F-L-L-I-I-Y-V-K-T-E-S-Q-N-K-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-V-P-T-A-F-L-L-I-I-Y-V-K-T-E-S-Q-N-K-K-N"} +{"text": "### FUNCTION Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains ### SEQUENCE -M-M-E-V-E-S-S-Y-S-D-F-I-S-C-D-R-S-G-R-R-N-A-V-P-D-I-Q-G-D-S-E-A-V-S-V-R-K-L-A-G-D-M-G-E-L-A-L-E-G-A-E-G-Q-A-E-V-G-T-S-D-K-E-A-S-S-Q-P-E-S-S-D-G-T-T-S-S"} +{"text": "### FUNCTION Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains ### SEQUENCE -M-M-E-V-E-S-S-Y-S-D-F-I-S-C-D-R-T-G-R-R-N-A-V-P-D-I-Q-G-D-S-E-A-V-S-V-R-K-L-A-G-D-M-G-E-L-A-L-E-G-A-E-G-Q-A-E-G-G-T-P-D-K-E-A-S-N-Q-P-Q-S-S-D-G-T-T-S-S"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-S-S-A-L-A-K-P-Q-M-R-G-L-L-A-R-R-L-R-I-H-I-V-G-A-F-V-V-S-L-G-V-A-A-F-Y-K-Y-A-V-A-E-P-R-K-K-A-Y-A-D-F-Y-R-N-Y-D-S-V-K-Y-F-E-E-M-R-K-A-G-V-F-Q-S-V-K"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-S-E-V-L-A-K-P-Q-M-R-G-L-L-A-R-R-L-R-I-H-M-V-G-A-F-L-I-S-L-G-V-A-A-L-Y-K-F-G-V-A-E-P-R-K-K-A-Y-A-D-F-Y-K-N-Y-S-P-E-K-D-F-E-E-M-K-K-A-G-V-F-R-S-I-K"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-S-E-V-L-V-K-P-Q-M-R-G-L-L-A-R-R-L-R-I-H-M-V-G-A-F-L-V-S-L-G-V-A-A-L-Y-K-F-G-V-A-E-P-R-K-K-A-Y-A-D-F-Y-K-N-Y-S-A-E-K-D-F-E-E-M-K-K-A-G-L-F-R-S-I-K"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-P-E-V-L-P-K-P-Q-M-R-G-L-L-A-K-R-L-R-F-H-M-V-T-A-F-V-L-S-L-G-V-A-A-L-Y-K-F-R-V-A-D-K-R-K-K-A-Y-A-D-F-Y-R-N-Y-D-A-M-K-D-F-E-E-M-R-K-A-G-I-F-Q-S-V-K"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-P-E-V-L-P-K-P-Q-M-R-G-L-L-A-R-R-L-R-F-H-M-V-T-G-F-V-L-S-L-G-V-A-A-L-Y-K-V-G-V-A-D-K-R-K-K-A-Y-A-D-F-Y-R-N-Y-D-A-M-K-D-F-E-E-M-R-K-A-G-I-F-Q-S-V-K"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-P-E-V-L-P-K-P-R-M-R-G-L-L-A-R-R-L-R-N-H-M-A-V-A-F-V-L-S-L-G-V-A-A-L-Y-K-F-R-V-A-D-R-R-K-K-A-Y-A-D-F-Y-R-N-Y-D-V-M-K-D-F-E-E-M-R-K-A-G-I-F-Q-S-V-K"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-S-S-G-A-L-T-K-P-Q-M-R-G-L-L-A-K-R-L-R-F-H-I-V-G-A-F-A-V-S-L-G-V-A-A-F-Y-K-F-A-V-A-E-P-R-K-K-A-Y-A-D-F-Y-R-N-Y-D-S-M-K-D-F-E-E-M-R-K-A-G-I-F-Q-S-A-K"} +{"text": "### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-M-I-T-A-C-L-V-L-F-G-T-V-W-A-K-E-G-Y-L-V-N-K-S-T-G-C-K-Y-G-C-F-W-L-G-K-N-E-N-C-D-M-E-C-K-A-K-N-Q-G-G-S-Y-G-Y-C-Y-S-F-A-C-W-C-E-G-L-P-D-S-T-P-T-Y-P-L-P-N-K-S-C-S-K-K"} +{"text": "### FUNCTION Heme transporter ### SEQUENCE -M-R-W-S-L-C-C-H-I-N-V-R-I-A-Y-T-I-C-G-I-I-I-G-L-F-W-A-C-V-Y-I-F-A-W-K-N-W-V-A-L-A-A-C-L-T-A-T-A-F-A-F-E-T-F-Y-F-Y-L-S-V-K-R-D-T-I-L-N-W-K-S-Q-T-F-Q-V-L-F-W-I-N-L-I-V-G-F-L-S-I-G-G-M-I-T-A-I-V-L-A-A-T-K-H-Q-G-V-S-N-K-D-Q-H-G-L-N-W-W-S-T-A-T-W-F-L-V-M-L-K-W-T-W-Q-N-A-F-I-A-R-Y-Y-G-K-L-L-T-K-S-I-I-H-P-E-E-P-D-D-P-S-T-W-K-F"} +{"text": "### FUNCTION Heme transporter ### SEQUENCE -M-S-S-K-I-S-S-S-R-C-C-T-L-F-C-H-V-N-T-R-I-A-L-T-I-L-D-I-L-I-G-F-S-N-I-L-S-Y-A-I-Q-F-H-N-W-S-A-L-T-L-T-A-M-V-T-L-V-A-C-H-T-L-Q-M-F-L-A-E-K-K-N-T-I-T-H-W-K-Y-S-T-F-K-W-I-M-W-I-D-I-T-L-G-F-L-A-L-G-C-F-V-V-C-F-I-I-A-G-V-T-E-I-E-F-T-N-L-Y-G-E-N-L-W-F-T-G-L-W-A-T-A-I-T-K-Y-T-W-Q-N-A-L-L-A-R-N-Y-S-N-Q-K-R-I-L-K-S-E-I-V-E-D-A"} +{"text": "### FUNCTION Nontoxic peptide ### SEQUENCE -M-K-N-Y-S-K-N-A-T-H-L-I-T-V-L-L-F-S-F-V-V-I-L-L-I-I-P-S-K-C-E-A-V-S-N-N-M-Q-P-L-E-A-R-S-A-D-L-V-Q-E-P-R-Y-I-I-N-V-P-P-R-C-P-P-G-S-K-F-I-K-N-R-C-R-V-I-V-P"} +{"text": "### FUNCTION Nontoxic peptide ### SEQUENCE -M-K-N-Y-S-K-N-A-T-Y-L-I-T-V-L-L-F-S-F-V-A-M-L-L-I-I-P-S-K-C-E-A-V-S-N-D-M-Q-P-L-E-A-R-S-A-D-L-V-P-E-P-R-Y-I-I-D-V-P-P-R-C-P-P-G-S-K-F-I-K-N-R-C-R-V-I-V-P"} +{"text": "### FUNCTION Nontoxic peptide ### SEQUENCE -M-K-N-Y-S-K-N-A-T-H-L-I-T-V-L-L-F-S-F-V-V-I-L-L-I-I-P-S-K-C-E-A-V-S-N-D-M-Q-P-L-E-A-R-S-A-D-L-I-P-E-P-R-Y-I-I-D-V-P-P-R-C-P-P-G-S-K-F-I-K-N-R-C-R-V-I-V-P"} +{"text": "### FUNCTION Nontoxic peptide ### SEQUENCE -M-K-N-Y-S-K-N-A-T-Y-L-I-T-V-L-L-F-S-F-V-T-M-L-L-I-I-P-S-K-C-E-A-V-S-N-D-M-Q-P-L-E-A-R-T-A-D-L-V-Q-Q-P-R-Y-I-I-D-V-P-P-R-C-P-P-G-S-K-F-V-H-K-R-C-R-V-I-V-P"} +{"text": "### FUNCTION Nontoxic peptide ### SEQUENCE -M-K-N-Y-S-K-N-A-T-Y-L-I-T-V-L-L-F-S-F-V-A-M-L-L-I-I-P-S-K-C-E-A-V-S-N-D-M-Q-P-L-E-A-R-T-A-D-L-V-Q-Q-P-R-Y-I-I-D-V-P-P-R-C-P-P-G-S-K-F-V-H-K-R-C-R-V-I-V-P"} +{"text": "### FUNCTION Functions downstream of migratory protein mig-13 and may play a role in the control of Q neuroblast migration during larval development ### SEQUENCE -M-M-M-T-M-A-A-D-Y-G-S-S-E-G-H-Y-D-T-P-W-E-F-L-A-R-P-N-S-V-R-F-S-T-A-D-V-R-L-S-T-S-A-A-G-D-A-K-V-S-P-H-G-S-P-S-L-C-S-S-S-S-F-V-N-Q-L-V-Q-I-G-N-S-A-V-D-A-R-R-K-V-P-R-D-E-S-K-R-R-R-P-S-D-S-E-I-Y-M-E-Q-N-M-N-R-V-E-A-E-K-R-L-E-N-R-N-L-G-D-Y-L-L-R-S-R-G-E-G-S-A-A-L-S-L-R-A-T-K-G-V-V-H-I-K-I-E-W-N-G-E-K-W-V-I-G-E-G-P-L-F-R-S-I-S-S-A-I-S-F-Y-R-R-H-P-L-P-I-R-G-A-D-H-L-V-L-K-N-Q-L-K-P-V"} +{"text": "### FUNCTION Involved in mitochondria homeostasis ### SEQUENCE -M-V-I-I-L-F-I-R-R-R-L-A-T-N-P-L-S-T-Q-M-C-I-A-G-T-I-S-G-S-G-D-C-L-A-Q-Y-L-S-H-N-Q-E-W-D-R-W-R-T-A-R-F-S-F-L-S-S-C-F-M-A-P-S-L-F-I-W-F-R-L-L-E-K-V-K-G-N-N-K-S-L-L-L-V-K-K-L-C-I-D-Q-L-C-F-S-P-C-F-N-A-A-I-L-F-N-L-R-L-L-Q-H-Q-S-A-E-K-S-W-D-L-L-K-E-D-W-F-N-I-Y-A-T-S-L-K-V-W-P-F-V-Q-V-V-N-L-C-F-V-P-L-N-Y-R-V-I-L-N-Q-V-V-A-F-F-W-N-C-Y-L-S-Y-I-T-Q-K-P-I-D-H-I-E-Q-F-Y"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -M-K-L-C-L-T-F-L-L-V-L-M-I-L-A-S-V-T-G-E-K-L-S-E-Q-T-L-R-R-A-A-R-K-N-K-G-P-R-C-W-V-G-R-V-H-C-T-Y-H-K-D-C-C-P-S-V-C-C-F-K-G-R-C-K-P-Q-S-W-G-C-W-S-G-P-T"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-P-S-F-C-K-A-N-G-K-P-C-S-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-A-P-S-T-N-W-I-L-P-G-C-S-T-S-S-F-F-K-I"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-P-S-F-C-K-A-D-E-K-P-C-E-Y-H-S-D-C-C-N-C-C-L-S-G-I-C-A-P-S-T-N-W-I-L-P-G-C-S-T-S-S-F-F-K-I"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-A-V-P-C-G-K-D-G-R-Q-C-R-N-H-A-D-C-C-N-C-C-P-F-G-T-C-A-P-S-T-N-R-I-L-P-G-C-S-T-G-M-F-L-T-R"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-A-V-P-C-G-K-D-G-R-Q-C-R-N-H-A-D-C-C-N-C-C-P-I-G-T-C-A-P-S-T-N-W-I-L-P-G-C-S-T-G-Q-F-M-T-R"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-A-V-P-C-G-K-D-G-R-Q-C-R-N-H-A-D-C-C-N-C-C-P-I-G-T-C-A-P-S-T-N-W-I-L-P-G-C-S-T-G-P-F-M-T-R"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-S-C-G-K-D-G-R-A-C-D-Y-H-A-D-C-C-N-C-C-L-G-G-I-C-K-P-S-T-S-W-I-G-C-S-T-N-V-F-L-T-R"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-G-R-K-C-G-Y-H-T-H-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-L-I-G-C-S-T-S-S-F-T"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-G-R-K-C-G-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-W-T-G-C-S-T-S-T-F-N"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-G-R-K-C-G-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-W-T-G-C-S-T-S-T-F-L-L-T-R"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-R-R-K-C-G-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-W-T-G-C-S-T-S-T-F-L-L-T-R"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-G-R-K-C-G-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-W-T-G-C-S-T-S-T-V-Q-L-T-R"} +{"text": "### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-G-R-K-C-G-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-W-T-G-C-S-T-S-T-F-D"} +{"text": "### FUNCTION Necessary for protein translocation in the endoplasmic reticulum ### SEQUENCE -M-D-Q-V-T-K-F-I-E-P-G-R-Q-F-A-K-D-S-I-R-L-V-K-R-C-T-K-P-D-R-K-E-F-Q-K-I-A-V-A-T-A-I-G-F-C-I-M-G-F-I-G-F-F-V-K-L-I-H-I-P-I-N-N-I-I-V-G-S"} +{"text": "### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -T-V-S-A-K-E-G-Y-L-V-K-K-S-N-G-C-K-Y-E-C-F-K-L-G-E-N-E-H-C-D-T-E-C-K-A-P-N-Q-G-G-S-Y-G-Y-C-D-T-F-E-C-W-C-E-G-L-P-E-S-T-P-T-W-P-L-P-N-K-S-C-G-K-K"} +{"text": "### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-M-I-I-G-C-L-V-L-I-G-T-V-W-T-K-E-G-Y-L-V-N-M-K-T-G-C-K-Y-G-C-Y-E-L-G-D-N-G-Y-C-D-R-K-C-K-A-E-S-G-N-Y-G-Y-C-Y-T-V-G-C-W-C-E-G-L-P-N-S-K-P-T-W-P-L-P-G-K-S-C-S-G-K"} +{"text": "### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-I-I-T-A-C-L-V-L-F-V-W-A-K-E-G-Y-L-V-N-K-S-T-G-C-K-Y-G-C-F-W-L-G-K-N-E-N-C-D-M-E-C-K-A-K-N-Q-G-G-S-Y-G-Y-C-Y-S-F-A-C-W-C-E-G-L-P-D-S-T-P-T-Y-P-L-P-N-K-S-C-S-K-K"} +{"text": "### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-M-I-T-A-C-L-A-E-I-G-T-V-W-A-K-E-G-Y-L-V-N-K-S-T-G-C-K-Y-G-C-F-W-L-G-K-N-E-N-C-D-K-E-C-K-A-K-N-Q-G-G-S-Y-G-Y-C-Y-S-F-A-C-W-C-E-G-L-P-D-S-T-P-T-Y-P-L-P-N-K-S-C-S-K-K"} +{"text": "### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-M-I-T-A-C-L-A-L-I-G-T-V-W-A-K-E-G-Y-I-V-N-Y-H-D-G-C-K-Y-E-C-Y-K-L-G-D-N-D-Y-C-L-R-E-C-K-L-R-Y-G-K-G-A-G-G-Y-C-Y-A-F-G-C-W-C-T-H-L-Y-E-Q-A-V-V-W-P-L-P-K-K-R-C-N-G-K"} +{"text": "### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-M-I-T-A-C-L-A-V-I-G-T-V-W-A-K-E-G-Y-I-V-N-Y-Y-D-G-C-K-Y-A-C-L-K-L-G-E-N-D-Y-C-L-R-E-C-K-A-R-Y-Y-K-S-A-G-G-Y-C-Y-A-F-A-C-W-C-T-H-L-Y-E-Q-A-V-V-W-P-L-P-N-K-T-C-Y-G-K"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-D-N-I-A-I-L-E-A-L-L-Y-T-S-G-D-E-G-L-E-Q-K-Q-I-I-D-I-L-D-I-N-L-N-Q-L-E-D-L-V-S-K-Y-H-S-H-G-L-T-I-Q-R-Y-G-S-T-Y-V-L-T-T-K-K-E-T-S-T-Y-I-E-Q-L-V-K-E-K-S-K-M-K-L-S-Q-A-A-M-E-T-L-S-I-I-A-Y-N-Q-P-L-T-R-G-D-I-E-M-I-R-G-I-N-S-D-G-A-V-K-T-L-I-A-R-G-L-V-E-A-K-D-V-D-H-S-R-S-H-H-L-I-T-T-D-L-F-L-N-V-F-G-I-E-N-L-D-A-L-P-T-T-E-E-D-E-A-E-M-D-E-F-F-S-N-L-V-N-Q-K-G-E-S-N-E"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-T-P-L-S-K-I-E-A-L-L-F-V-A-G-E-D-G-L-S-L-R-Q-L-A-T-L-L-D-I-P-V-T-A-L-L-Q-Q-L-E-K-M-A-Q-K-Y-E-R-D-D-N-S-A-L-S-L-L-E-S-S-K-T-Y-K-L-V-T-K-K-D-Y-A-D-L-L-R-Q-Y-S-K-T-P-I-N-Q-S-L-S-R-A-S-L-E-V-L-S-I-I-A-Y-K-Q-P-I-T-R-I-E-V-D-N-I-R-G-V-N-S-S-S-A-I-S-K-L-Q-A-F-D-L-I-Q-E-A-G-K-K-E-V-L-G-R-P-N-L-Y-V-T-S-D-Y-F-L-D-Y-M-G-I-N-S-L-E-E-L-P-D-A-S-S-I-E-L-K-D-E-E-F-T-L-F-D-N-K-E-N-E-E-Q-I-S-E-N-V-K-E-E-N-E-N"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-T-Y-L-G-S-I-E-A-L-L-F-V-A-G-E-D-G-L-S-L-R-Q-M-A-E-L-L-S-L-T-P-S-A-L-I-Q-Q-L-E-K-L-A-K-R-Y-E-E-D-D-D-S-S-L-L-L-L-E-T-A-Q-T-Y-K-L-V-T-K-D-S-Y-M-T-L-L-R-D-Y-A-K-A-P-I-N-Q-S-L-S-R-A-S-L-E-V-L-S-I-I-A-Y-K-Q-P-I-T-R-I-E-I-D-D-I-R-G-V-N-S-S-G-A-I-T-R-L-I-A-F-G-L-I-K-E-A-G-K-K-E-V-L-G-R-P-N-L-Y-E-T-T-N-Y-F-L-D-Y-M-G-I-N-Q-L-D-D-L-I-D-A-S-S-I-E-L-V-D-E-E-V-S-L-F-S-M-D-S-I-N-T-E-D-K-E-N-N-E-N"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-T-Y-L-G-S-I-E-A-L-L-F-V-A-G-E-D-G-L-S-L-R-Q-M-A-E-L-L-S-L-T-P-S-A-L-I-Q-Q-L-E-K-L-A-K-R-Y-E-E-D-D-D-S-S-L-L-L-L-E-T-A-Q-T-Y-K-L-V-T-K-D-S-Y-M-T-L-L-R-D-Y-A-K-A-P-I-N-Q-S-L-S-R-A-S-L-E-V-L-S-I-I-A-Y-K-Q-P-I-T-R-I-E-I-D-D-I-R-G-V-N-S-S-G-A-I-T-R-L-I-A-F-G-L-I-K-E-A-G-K-K-E-V-L-G-R-P-N-L-Y-E-T-T-N-Y-F-L-D-Y-M-G-I-N-Q-L-D-D-L-I-D-A-S-S-I-E-L-V-D-E-E-V-S-L-F-S-M-D-S-I-N-T-E-D-K-E-N-N-E-N"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-A-D-R-L-T-Q-L-Q-D-A-V-N-S-L-A-D-Q-F-C-N-A-I-G-V-L-Q-Q-C-A-P-P-A-S-F-S-N-I-Q-T-A-I-N-K-D-Q-P-S-N-P-T-E-E-Y-A-Q-L-F-A-A-L-I-A-R-T-A-K-D-V-D-V-L-I-D-S-L-P-S-E-E-S-T-A-A-L-Q-A-A-S-L-R-Q-L-E-E-E-N-Q-E-A-A-A-R-L-E-E-V-V-Y-R-G-D-A-L-L-E-K-I-Q-T-A-L-A-D-I-A-Q-S-Q-L-R-T-R-S-G-A-P-S-Q-Q-T-P-P-E-S"} +{"text": "### FUNCTION Involved in the biogenesis of the 60S ribosomal subunit Ensures the docking of GTPBP4/NOG1 to pre-60S particles ### SEQUENCE -M-R-I-E-K-C-Y-F-C-S-A-P-V-Y-P-G-H-G-M-M-F-V-R-N-D-C-K-V-F-R-F-C-R-S-K-C-H-K-N-F-K-K-K-R-N-P-R-K-T-R-W-T-K-A-F-R-K-S-A-G-K-E-L-T-V-D-N-S-L-E-F-E-K-R-R-N-T-P-V-K-Y-N-R-E-L-W-S-K-T-V-E-A-M-R-K-V-E-S-I-K-H-K-R-Q-A-R-F-I-M-N-R-L-K-K-G-K-E-L-E-K-A-A-D-I-S-E-V-K-K-N-I-H-L-I-K-A-P-H-A-G-Q-A-K-Q-L-E-D-K-M-V-Q-K-L-A-E-D-V-E-M-D-E"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-G-R-V-R-T-K-T-V-K-K-A-A-R-V-I-I-E-K-Y-Y-T-R-L-G-N-D-F-H-T-N-K-R-V-C-E-E-I-A-I-I-P-S-K-K-L-R-N-K-I-A-G-Y-V-T-H-L-M-K-R-I-Q-R-G-P-V-R-G-I-S-I-K-L-Q-E-E-E-R-E-R-R-D-N-Y-V-P-E-V-S-A-L-D-Q-E-I-I-E-V-D-P-D-T-K-E-M-L-K-L-L-D-F-G-S-L-S-N-L-Q-V-T-Q-P-T-V-G-M-N-F-K-T-P-R-G-A-L"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-Q-N-D-A-G-E-F-V-D-L-Y-V-P-R-K-C-S-A-S-N-R-I-I-G-A-K-D-H-A-S-I-Q-I-N-I-A-E-V-D-R-V-T-G-R-F-N-G-Q-F-K-T-Y-A-I-C-G-A-I-R-R-M-G-E-A-D-D-S-L-L-R-L-A-K-T-D-S-I-V-A-K"} +{"text": "### FUNCTION May form part of 2 intersubunit bridges in the assembled ribosome Upon binding to MALSU1, intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation ### SEQUENCE -M-A-L-S-L-S-G-L-I-L-P-K-L-M-Q-Q-R-A-F-S-V-S-S-A-V-S-A-I-Q-K-L-T-R-V-R-V-V-D-N-S-T-L-G-N-A-H-H-H-R-P-P-K-V-I-H-V-Y-N-K-N-G-V-G-K-V-G-D-R-V-L-L-A-I-K-G-Q-K-K-K-A-I-I-V-G-H-K-M-P-G-A-R-M-T-P-R-F-D-S-N-N-V-V-L-I-E-D-N-G-N-P-T-G-T-R-I-K-A-P-L-P-T-H-L-R-K-L-E-G-E-Y-S-K-L-L-A-I-A-Q-R-F-V"} +{"text": "### FUNCTION Component of the COP9 signalosome complex ### SEQUENCE -M-P-V-C-V-M-M-A-E-L-D-E-K-L-L-L-Q-F-E-T-Q-E-L-E-A-P-G-G-I-A-T-P-Q-V-Y-S-Q-L-L-V-L-Y-L-L-H-N-D-M-N-N-A-R-Y-L-W-K-R-I-P-Q-A-I-K-T-A-N-P-E-M-A-A-I-W-A-V-G-Q-R-I-W-Q-R-D-F-P-G-I-Y-S-A-I-A-A-Y-Q-W-S-E-S-I-L-P-V-M-E-A-L-R-E-S-T-R-R-R-A-Y-G-L-V-A-Q-A-Y-T-S-I-S-A-E-D-F-A-A-F-V-G-Y-S-V-E-E-A-V-K-G-V-V-S-H-G-W-Q-A-D-P-N-T-R-M-I-M-P-Q-K-P-D-P-P-P-V-S-L-V-P-N-E-Q-Q-L-A-R-L-T-D-Y-V-A-F-L-E-N"} +{"text": "### FUNCTION Plays a role as translation enhancer and involved in cell cycle regulation ### SEQUENCE -M-F-K-K-F-D-E-K-E-N-V-S-N-C-I-Q-L-K-T-S-V-I-K-G-I-K-N-Q-L-L-D-Q-F-P-N-I-D-D-W-L-N-Q-I-M-P-K-K-D-P-V-K-I-V-R-C-H-E-H-I-E-I-L-T-V-N-G-E-L-L-F-F-R-Q-R-E-G-P-F-Y-P-T-L-R-L-L-H-K-Y-P-F-I-L-P-H-Q-Q-V-D-K-G-A-I-K-F-V-L-S-G-A-N-I-M-C-P-G-L-T-S-P-G-A-K-L-Y-P-A-E-S-D-T-V-V-A-I-M-A-E-G-K-Q-H-A-L-C-V-G-V-M-K-M-S-A-D-D-I-E-K-V-N-M-G-I-G-I-E-N-V-H-Y-L-N-D-G-L-W-H-M-K-T-Y-K"} +{"text": "### FUNCTION As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane Similarly, the bag6/bat3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum The bag6/bat3 complex also plays a role in the endoplasmic reticulum-associated degradation , a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome ### SEQUENCE -M-I-L-T-V-K-P-L-Q-G-K-E-C-N-V-Q-V-T-E-N-E-K-V-S-T-V-K-E-L-V-S-E-R-L-N-I-P-A-S-Q-Q-R-L-L-Y-K-G-K-A-L-A-D-E-H-R-L-S-D-Y-S-I-G-P-E-A-K-L-N-L-V-V-R-P-A-G-E-R-S-S-G-A-V-G-T-S-S-A-N-N-D-K-G-G-S-G-V-W-Q-L-L-S-T-V-L-A-K-H-F-S-P-A-D-A-A-K-V-Q-E-Q-L-I-K-D-Y-E-R-S-L-R-Q-L-S-L-D-D-I-E-R-L-A-S-R-L-L-H-P-E-T-E-V-M-D-T-S-Y-M-D"} +{"text": "### FUNCTION Specific component of the STT3A-containing form of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-E-T-L-F-S-L-P-F-T-V-L-E-C-P-N-V-K-L-K-K-P-S-W-L-H-M-P-S-A-M-T-V-Y-A-V-V-I-V-S-Y-F-L-I-T-G-G-I-I-Y-D-V-I-V-E-P-P-S-V-G-S-M-T-D-E-H-G-H-Q-R-P-V-A-F-L-A-Y-R-V-N-G-Q-Y-I-M-E-G-L-A-S-S-F-L-F-T-M-G-G-L-G-F-I-I-L-D-R-S-N-A-P-N-I-P-K-L-N-R-F-L-L-L-F-I-G-F-V-S-V-L-L-S-F-F-M-A-R-V-F-M-R-M-K-L-P-G-Y-L-M-G"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-K-A-S-G-T-L-R-E-Y-K-V-V-G-R-L-L-P-S-V-K-N-P-A-P-P-L-Y-R-M-R-I-F-A-P-N-H-V-V-A-K-S-R-F-W-Y-F-V-S-Q-L-R-K-M-K-K-A-S-G-E-I-V-Y-C-G-L-V-F-E-K-S-P-L-K-V-K-N-F-G-I-W-L-R-Y-D-S-R-S-G-T-H-N-M-Y-R-E-Y-R-D-L-T-T-S-G-A-V-T-Q-C-Y-R-D-M-G-A-R-H-R-A-R-A-H-A-I-Q-I-M-K-V-Q-V-I-A-A-N-K-C-R-R-P-A-I-K-Q-F-H-D-S-K-I-K-F-P-L-P-H-R-V-L-R-R-Q-H-K-P-R-F-T-T-K-R-P-N-T-F-F"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-V-Q-R-L-T-Y-R-R-R-L-S-Y-N-T-A-S-N-K-T-R-L-S-R-T-P-G-N-R-I-V-Y-L-Y-T-K-K-T-G-K-S-P-K-S-A-C-G-I-C-P-G-R-L-R-G-I-R-A-V-R-P-Q-V-L-M-R-L-S-K-T-K-K-H-V-S-R-A-Y-G-G-S-M-C-A-K-C-V-R-D-R-I-K-R-A-F-L-I-E-E-Q-K-I-V-V-K-V-L-K-A-Q-A-Q-T-Q-K-S-K"} +{"text": "### FUNCTION Probable hormone that may attenuate cell proliferation and induce senescence in the central nervous system ### SEQUENCE -M-V-V-L-L-F-L-L-V-I-L-L-C-P-D-S-T-N-G-N-K-L-R-K-M-L-Q-K-R-E-A-V-E-P-S-K-P-I-V-S-V-K-E-S-K-A-N-E-F-L-N-S-L-K-R-P-K-R-Q-L-W-D-R-T-R-P-E-V-Q-Q-W-Y-Q-Q-F-L-Y-M-G-F-D-E-A-K-Y-E-D-D-M-S-Y-W-K-N-Q-G-R-G-G-S-E-Y-Y-G-G-F-H-Q-H-H-Y-D-E-D-A-A-I-G-P-R-N-P-Y-T-Y-R-H-G-A-G-V-N-Y-D-D-Y"} +{"text": "### FUNCTION Regulates dendritic and spine growth and synaptic transmission ### SEQUENCE -M-A-K-S-L-R-S-K-W-K-R-K-M-R-A-E-K-R-K-K-N-A-P-K-E-L-A-R-L-K-T-V-L-A-K-G-S-N-V-L-M-D-D-V-K-E-I-A-T-V-V-P-A-K-K-I-N-E-K-M-D-L-D-V-D-A-P-E-G-E-S-S-K-M-D-T-E-L-K-R-N-K-K-N-L-R-D-Q-H-G-Q-Y-P-V-W-F-N-Q-R-Q-Q-K-K-L-K-S-Q-C-G-K-K-K-G-K-S-K-Q-A-K-K-L-A-W"} +{"text": "### FUNCTION Molecular adapter that acts as a bridge between proteins, and which is involved skeletal muscle development Functions as signal transducer for MSTN during skeletal muscle regeneration and myogenesis ### SEQUENCE -M-A-C-G-A-T-L-K-R-S-M-E-F-E-A-L-M-S-P-Q-S-P-K-R-R-R-C-A-P-L-P-G-S-P-A-T-P-S-P-Q-R-C-G-I-R-P-E-I-Q-Q-G-Q-Q-Q-P-L-G-G-D-L-R-L-T-P-E-Q-I-L-Q-N-I-K-Q-E-Y-T-R-Y-Q-R-R-R-Q-L-E-G-A-F-N-Q-G-E-A-G-V-S-N-E-V-Q-A-S-C-S-S-L-T-A-P-S-S-P-G-S-L-V-K-K-D-Q-P-T-F-S-L-R-Q-V-G-I-L-C-E-R-L-L-K-D-H-E-D-K-I-R-E-E-Y-E-Q-I-L-N-I-K-L-A-E-Q-Y-E-S-F-V-K-F-T-H-D-Q-I-M-R-R-Y-G-A-R-P-T-S-Y-V-S"} +{"text": "### FUNCTION May form with the serine/threonine protein phosphatase ctdnep1 an active complex dephosphorylating and activating lipins Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics May also indirectly regulate the production of lipid droplets and triacylglycerol ### SEQUENCE -M-N-S-L-E-Q-A-E-D-L-K-A-F-E-R-R-L-T-E-Y-V-S-C-L-Q-P-T-T-G-R-W-R-M-L-L-I-V-V-S-V-C-T-A-T-G-A-W-N-W-L-I-D-P-E-T-Q-K-V-S-F-F-T-S-L-W-N-H-P-F-F-T-I-S-C-I-T-L-I-G-L-F-F-A-G-I-H-K-R-V-V-A-P-S-I-I-A-A-R-C-R-T-V-L-A-E-Y-N-M-S-C-D-D-T-G-K-L-I-L-K-P-R-P-H-V-Q"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-I-I-Y-K-D-C-I-T-E-D-E-M-F-S-D-I-Y-K-I-I-E-T-P-D-G-M-C-L-E-V-E-G-K-V-I-Q-R-E-E-G-A-I-D-D-A-L-I-G-G-N-A-S-A-E-F-Q-E-D-D-V-G-G-S-S-L-T-S-G-V-D-I-V-M-N-H-K-L-Q-E-T-G-F-T-K-D-S-Y-K-N-Y-I-K-D-Y-V-K-Q-L-K-A-H-L-E-K-T-N-P-E-R-V-N-T-F-M-K-G-A-Q-E-T-V-K-K-I-L-G-N-F-K-N-Y-Q-F-Y-T-G-E-R-M-N-P-D-G-M-V-G-L-L-D-Y-R-E-D-G-I-T-P-F-M-I-F-F-K-D-G-L-I-I-E-K-C"} +{"text": "### FUNCTION Has no ubiquitin ligase activity on its own The ube2v2/ube2n heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63' This type of poly-ubiquitination does not lead to protein degradation by the proteasome Mediates transcriptional activation of target genes Plays a role in the control of progress through the cell cycle and differentiation Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage ### SEQUENCE -M-A-V-C-A-G-I-K-V-P-R-N-F-R-L-L-E-E-L-E-E-G-Q-K-G-V-G-D-G-T-V-S-W-G-L-E-D-D-E-D-M-T-L-T-R-W-T-G-M-I-I-G-P-P-R-T-N-Y-E-N-R-I-Y-S-L-R-L-E-C-G-P-K-Y-P-E-A-P-P-T-V-R-F-V-T-K-M-N-M-N-G-I-N-N-S-N-G-T-V-D-Y-R-S-I-P-V-L-A-K-W-Q-N-S-F-S-I-K-V-L-L-Q-E-L-R-R-L-M-M-S-K-E-N-M-K-L-P-Q-P-P-E-G-Q-T-Y-N-N"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-S-M-L-R-L-Q-K-R-L-A-S-S-V-L-R-C-G-K-K-K-V-W-L-D-P-N-E-T-N-E-I-A-N-A-N-S-R-Q-Q-I-R-K-L-V-K-D-G-L-I-I-R-K-P-V-T-V-H-S-R-A-R-C-R-K-N-T-L-A-R-R-K-G-R-H-M-G-I-G-K-R-K-G-T-A-N-A-R-M-P-E-K-L-S-W-M-R-R-M-R-I-L-R-R-L-L-R-R-Y-R-E-S-K-K-I-D-R-H-M-Y-H-S-L-Y-L-K-V-K-G-N-V-F-K-N-K-R-I-L-M-E-H-I-H-K-L-K-A-D-K-A-R-K-K-L-L-A-D-Q-A-E-A-R-R-S-K-T-K-E-A-R-K-R-R-E-E-R-L-Q-A-K-K-E-E-I-I-K-S-L-S-K-E-E-E-S-G-K-K"} +{"text": "### FUNCTION Involved in the interconversion between alpha- and beta-L-fucoses ### SEQUENCE -M-V-I-L-K-G-I-P-S-V-L-T-P-E-L-L-Y-V-L-A-Q-M-G-H-G-D-E-L-V-L-A-D-A-N-F-P-T-S-S-V-C-K-C-G-P-V-E-I-R-A-D-G-V-R-I-P-E-L-L-K-A-I-L-K-L-F-P-L-D-T-Y-D-E-S-A-A-V-M-D-L-V-P-S-D-L-L-K-G-L-K-V-P-I-W-D-Q-Y-S-E-L-L-K-Q-A-G-S-D-G-N-M-K-P-V-E-R-F-A-F-Y-E-R-A-K-K-A-F-A-V-V-A-T-G-E-T-A-L-Y-G-N-L-I-I-K-K-G-V-I-P-P-E-E-Q-C"} +{"text": "### FUNCTION Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation ### SEQUENCE -M-A-L-L-S-P-Y-S-K-V-P-E-L-N-T-A-T-V-L-L-V-E-N-E-E-E-L-Q-N-K-L-A-N-A-I-V-Q-H-E-K-D-F-N-V-N-V-R-L-A-K-K-L-P-L-P-V-E-N-K-E-A-R-P-R-I-D-L-I-V-F-I-V-S-L-L-S-E-R-S-L-Q-S-A-E-S-S-L-S-H-L-H-S-D-C-F-L-G-K-V-C-F-L-V-T-D-A-R-C-G-S-H-T-Q-E-R-L-V-S-V-R-K-L-A-A-S-H-H-C-P-V-I-C-A-E-H-R-T-A-D-G-V-S-A-A-A-L-R-L-L-N-I-L-Q-V-S-A-G-M-T-P-M-S-T-T-A-L-Y-L-S-T-L-T-R-C-S-L-T-S-D-L-Q-E-D-Y-L-Q"} +{"text": "### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-E-C-A-K-T-G-T-C-N-C-G-G-S-C-T-C-T-K-C-S-C-K-S-C-K-K-S-C-C-D-C-C-P-S-G-C-S-K-C-A-S-G-C-V-C-K-G-K-T-C-D-T-S-C-C-Q"} +{"text": "### FUNCTION Indispensable for the control of thyroid structure and metabolism May play some role in the biological processes of the immature fishes ### SEQUENCE -M-R-V-V-L-L-A-S-G-V-L-C-L-L-A-G-Q-V-L-S-I-C-S-P-V-D-Y-T-L-Y-V-E-K-P-E-C-D-F-C-V-A-I-N-T-T-I-C-M-G-F-C-Y-S-L-D-P-N-V-V-G-P-A-V-K-R-L-A-V-Q-R-G-C-T-Y-Q-A-V-E-Y-R-T-A-E-L-P-G-C-P-P-H-V-D-P-R-F-S-Y-P-V-A-L-H-C-T-C-R-A-C-D-P-A-R-D-E-C-T-H-R-A-S-A-D-G-D-R-C-S-K-P-L-L-L-H-M-H-A-Y-P-G-Q-S-N-H-I-Q-T-L"} +{"text": "### FUNCTION Urotensin is found in the teleost caudal neurosecretory system It has a suggested role in osmoregulation and as a corticotropin-releasing factor ### SEQUENCE -M-M-W-K-L-L-L-L-F-A-L-L-L-T-V-L-E-P-L-L-G-H-P-V-V-Q-S-A-E-M-S-F-G-R-P-V-V-V-E-E-E-Q-A-L-N-P-E-E-L-S-F-S-E-Q-A-Y-L-S-H-D-A-A-G-F-G-Y-P-S-L-I-S-G-D-I-S-S-D-G-L-R-T-A-G-F-V-P-S-Q-A-V-K-E-A-L-L-E-K-P-L-W-S-R-F-L-G-S-R-K-Q-Y-H-K-R-G-S-N-T-E-C-F-W-K-Y-C-V"} +{"text": "### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-E-C-S-K-T-G-N-C-T-C-G-G-S-C-T-C-K-N-C-S-C-T-S-C-K-K-S-C-C-S-C-C-P-S-G-C-S-K-C-A-S-G-C-V-C-K-G-K-T-C-D-T-S-C-C-Q"} +{"text": "### FUNCTION Acts as a positive cofactor of GATA transcription factors to establish the identity of the ventral mesoderm during gastrulation Down-regulation in the dorsal mesoderm is necessary for the proper formation of this territory since, when present, lmo4 may bind ldb1 and restrict the availability of this cofactor for Spemman organizer transcription factors At neurula stages, suppresses primary neuron differentiation and modulates gene expression at the Isthmic Organizer of the midbrain-hindbrain boundary ### SEQUENCE -M-V-N-N-R-I-S-E-S-T-T-T-A-V-S-N-N-G-S-P-P-K-A-C-A-G-C-G-G-K-I-A-D-R-F-L-L-Y-S-M-D-R-Y-W-H-T-R-C-L-K-C-S-C-C-Q-A-Q-L-G-E-I-G-T-S-C-Y-T-K-S-G-M-I-L-C-R-N-D-Y-I-R-L-F-G-N-S-G-A-C-N-A-C-G-Q-S-I-P-A-S-E-M-V-M-R-A-Q-G-S-V-Y-H-L-K-C-F-T-C-A-T-C-R-N-R-L-V-P-G-D-R-F-H-Y-V-N-G-T-I-F-C-E-H-D-R-P-T-G-L-L-N-G-H-L-N-P-L-Q-S-N-P-L-Q-G-S-P-M-L-P-D-Q-K-V-C"} +{"text": "### FUNCTION Seems to act as a signaling molecule involved in the maintenance of iron homeostasis Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages May also have antimicrobial activity ### SEQUENCE -M-K-A-F-S-V-A-V-V-L-V-I-A-C-M-F-I-L-E-S-T-A-V-P-F-S-E-V-R-T-E-E-V-G-S-F-D-S-P-V-G-E-H-Q-Q-P-G-G-E-S-M-H-L-P-E-P-F-R-F-K-R-Q-I-H-L-S-L-C-G-L-C-C-N-C-C-H-N-I-G-C-G-F-C-C-K-F"} +{"text": "### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-T-C-L-N-C-P-E-V-F-C-K-K-F-Q-T-C-R-N-G-E-K-I-C-F-K-K-F-D-E-R-K-L-F-G-K-R-Y-R-R-G-C-A-A-T-C-P-E-A-K-P-R-E-I-V-Q-C-C-S-T-D-R-C-N-R"} +{"text": "### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-T-C-L-N-C-P-E-M-F-C-G-K-F-Q-T-C-R-N-G-E-K-I-C-F-K-M-L-Q-Q-R-R-P-F-S-L-R-Y-I-R-G-C-A-A-T-C-P-G-T-K-P-R-D-M-V-E-C-C-S-T-D-R-C-N-R"} +{"text": "### FUNCTION May be involved in redox reactions associated with the formation of disulfide bonds May contribute to the quality control of protein folding in the endoplasmic reticulum ### SEQUENCE -M-A-G-E-V-Y-L-L-W-L-L-P-L-L-Q-G-L-A-S-Y-G-A-E-L-S-S-E-A-C-R-E-L-G-F-S-S-N-L-L-C-S-S-C-E-L-L-G-Q-F-S-L-N-Q-L-D-L-P-C-R-Q-C-C-Q-E-E-A-Q-L-E-N-R-K-L-Y-P-G-A-I-L-E-V-C-G-U-K-L-G-R-F-P-Q-V-Q-A-F-V-R-S-D-K-P-K-L-F-R-G-L-Q-I-K-Y-V-R-G-S-D-P-V-L-K-L-L-D-D-N-G-N-I-A-E-E-L-S-I-L-K-W-N-T-D-S-V-E-E-F-L-S-E-K-L-E-R-I"} +{"text": "### FUNCTION Exhibits natriuretic and vasodepressant activity Has cGMP-stimulating activity May help to regulate body fluid homeostasis in a variety of aquatic environments ### SEQUENCE -M-N-L-S-Y-L-V-A-C-G-L-M-I-T-L-L-S-V-R-M-G-A-K-P-L-S-Q-A-Q-Q-K-S-F-R-S-L-L-G-E-E-L-A-E-F-L-E-S-E-E-K-E-R-R-L-D-A-V-R-S-R-L-R-L-L-R-D-L-R-M-D-T-R-A-R-G-V-W-A-R-L-L-N-D-Q-P-V-P-R-R-H-K-T-G-I-K-K-G-G-S-S-R-S-G-C-F-G-H-K-M-D-R-I-G-T-I-S-G-M-G-C"} +{"text": "### FUNCTION Exhibits natriuretic and vasodepressant activity Has cGMP-stimulating activity May help to regulate body fluid homeostasis in a variety of aquatic environments ### SEQUENCE -M-S-L-N-L-P-G-Y-A-L-F-F-I-L-L-V-A-S-S-G-A-K-P-A-P-D-L-Q-I-L-E-P-P-L-S-S-L-E-E-Q-E-E-M-Q-E-E-V-Q-E-K-V-Q-E-Q-Q-E-E-V-Q-E-K-V-Q-E-Q-Q-E-E-V-Q-E-Q-Q-E-E-V-Q-E-Q-Q-E-E-Q-Q-E-E-V-Q-E-R-G-R-G-T-G-D-V-L-L-R-A-Q-L-D-S-S-T-W-A-L-Q-K-D-D-V-L-M-R-L-F-K-D-L-L-R-T-S-K-R-S-R-S-R-Y-K-K-G-G-L-R-S-C-F-G-V-R-L-A-R-I-G-S-F-S-G-L-G-C"} +{"text": "### FUNCTION Exhibits natriuretic and vasodepressant activity Has cGMP-stimulating activity May help to regulate body fluid homeostasis in a variety of aquatic environments ### SEQUENCE -M-A-A-S-S-S-S-F-V-P-L-V-L-L-F-L-A-I-P-V-E-P-R-P-S-M-T-R-D-E-A-Q-V-L-R-A-L-F-G-A-R-L-S-S-I-I-S-T-P-V-N-T-D-D-I-A-E-L-L-P-R-R-P-G-P-P-R-S-F-G-A-S-P-G-A-L-R-G-L-T-R-G-S-E-G-G-S-R-F-L-L-D-F-L-Q-Q-Q-S-K-T-T-R-R-G-R-S-S-M-V-G-G-R-G-C-F-G-M-K-I-D-R-I-G-S-I-S-G-L-G-C"} +{"text": "### FUNCTION Exhibits natriuretic and vasodepressant activity Has cGMP-stimulating activity May help to regulate body fluid homeostasis in a variety of aquatic environments ### SEQUENCE -M-L-C-P-A-L-L-C-A-A-L-L-L-L-T-P-V-E-I-T-D-A-R-A-L-Q-Q-P-S-D-A-A-Q-F-M-E-Q-F-L-E-S-Y-N-D-L-L-T-L-D-D-L-E-N-M-L-N-S-H-P-E-D-Q-S-N-L-S-S-S-K-A-D-E-Y-P-K-W-A-E-A-D-T-P-W-L-R-L-L-R-G-A-L-A-N-Q-K-R-A-E-P-D-R-S-R-R-G-W-N-R-G-C-F-G-L-K-L-D-R-I-G-S-M-S-G-L-G-C"} +{"text": "### FUNCTION Virion protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-R-G-C-D-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-Y-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V"} +{"text": "### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-N-S-L-S-I-F-F-I-V-V-A-T-A-A-V-C-L-L-F-I-Q-G-Y-S-I-Y-E-N-Y-G-N-I-K-E-F-N-A-T-H-A-A-F-E-Y-S-K-S-I-G-G-T-P-A-L-D-R-R-V-Q-D-V-N-D-T-I-S-D-V-K-Q-K-W-R-C-V-V-Y-P-G-N-G-F-V-S-A-S-I-F-G-F-Q-A-E-V-G-P-N-N-T-R-S-I-R-K-F-N-T-M-Q-Q-C-I-D-F-T-F-S-D-V-I-N-I-D-I-Y-N-P-C-V-A-P-N-I-N-N-A-E-C-Q-F-L-K-S-V-L"} +{"text": "### FUNCTION Has thioltransferase and dehydroascorbate reductase activities ### SEQUENCE -M-A-E-E-F-V-Q-Q-R-L-A-N-N-K-V-T-I-F-V-K-F-T-C-P-F-C-R-N-A-L-D-I-L-N-K-F-S-F-K-R-G-A-Y-E-I-V-D-I-K-E-F-K-P-E-N-E-L-R-D-Y-F-E-Q-I-T-G-G-R-T-V-P-R-I-F-F-G-K-T-S-I-G-G-Y-S-D-L-L-E-I-D-N-M-D-A-L-G-D-I-L-S-S-I-G-V-L-R-T-C"} +{"text": "### FUNCTION Contributes to vaccinia virus virulence in mice but not to replication in cell culture ### SEQUENCE -M-D-P-V-N-F-I-K-T-Y-A-P-R-G-S-I-I-F-I-N-Y-T-M-S-L-T-S-H-L-N-P-S-I-E-K-H-V-G-I-Y-Y-G-T-L-L-S-E-H-L-V-V-E-S-T-Y-R-K-G-V-R-I-V-P-L-D-S-F-F-E-G-Y-L-S-A-K-V-Y-M-L-E-N-I-Q-V-M-K-I-A-A-D-T-S-L-T-L-L-G-I-P-Y-G-F-G-H-D-R-M-Y-C-F-K-L-V-A-D-C-Y-K-N-A-G-I-D-T-S-S-K-R-I-L-G-K-D-I-F-L-S-Q-N-F-T-D-D-N-R-W-I-K-I-Y-D-S-N-N-L-T-F-W-Q-I-D-Y-L-K-G"} +{"text": "### FUNCTION Involved in host translation shutoff without degradating host RNA By suppressing host gene expression, facilitates the evasion from host type I interferon immune response ### SEQUENCE -M-N-N-S-K-D-N-P-F-C-G-A-I-A-R-K-A-R-I-Y-L-R-E-G-L-D-C-V-Y-F-L-N-K-A-G-Q-A-E-S-C-P-A-C-T-S-L-V-F-Q-G-K-T-C-E-E-H-K-Y-N-N-N-L-L-S-W-Q-A-V-R-Q-L-E-R-Q-M-P-Q-L-Q-S-S-N"} +{"text": "### FUNCTION Regulates HCFC1 activity by modulating its subcellular localization Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus ### SEQUENCE -M-I-L-Q-Q-P-L-E-R-G-P-P-G-R-D-P-R-A-T-T-G-V-T-L-G-L-D-T-R-E-P-L-H-K-H-F-L-S-E-E-N-M-A-T-H-F-S-R-L-S-L-H-N-D-H-P-Y-C-S-P-P-V-T-F-P-E-A-L-P-P-L-R-S-P-C-P-E-L-L-L-W-R-Y-P-G-S-L-I-P-E-A-L-R-L-L-R-L-G-D-N-P-S-P-Y-Y-S-A-S-P-A-G-E-I-M-E-L"} +{"text": "### FUNCTION Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation ### SEQUENCE -M-S-S-S-T-S-C-P-I-P-G-C-R-D-Q-L-P-D-G-Y-S-T-T-P-G-G-T-L-Y-A-T-T-P-G-G-T-R-I-I-Y-D-R-K-F-L-L-E-C-K-N-S-P-I-A-R-T-P-P-C-C-L-P-Q-I-P-G-V-T-T-L-P-A-V-P-P-S-K-L-E-L-L-K-E-Q-K-Q-T-E-V-E-I-T-D-D-E-Q-F-E-M-D-M"} +{"text": "### FUNCTION Involved in the early part of the secretory pathway ### SEQUENCE -M-T-N-V-Y-S-L-D-G-I-L-V-F-G-L-L-F-V-C-T-C-A-Y-F-K-K-V-P-R-L-K-T-W-L-L-S-E-K-K-G-V-W-G-V-F-Y-K-A-A-V-I-G-T-R-L-H-A-A-V-A-I-A-C-I-V-M-A-F-Y-V-L-F-I-K"} +{"text": "### FUNCTION Cytokine with immunoregulatory activity May promote the transition between innate and adaptive immunity Induces the production of IgG ### SEQUENCE -V-V-I-F-L-G-T-V-A-H-K-T-S-P-Q-R-P-D-R-L-L-I-R-L-R-H-L-V-D-N-V-E-Q-L-K-I-Y-V-N-D-L-D-P-E-L-L-P-A-P-Q-D-V-K-E-H-C-A-H-S-A-F-A-C-F-Q-K-A-K-L-K-P-A-N-T-G-S-N-K-T-I-I-S-D-L-V-T-Q-L-R-R-R-L-P-A-T-K-A-E-K-K-Q-Q-S-L-V-K-C-P-S-C-D-S-Y-E-K-K-T-P-K-E-F-L-E"} +{"text": "### FUNCTION Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine proteins that have critical roles in mRNA metabolism Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions ### SEQUENCE -M-A-D-N-Q-V-P-K-R-H-C-Q-Y-P-L-L-A-L-L-N-T-P-D-Q-P-I-P-H-H-V-P-T-T-P-Q-K-Q-S-R-A-R-R-R-L-E-N-E-L-E-S-T-A-Q-T-S-N-H-T-A-P-Q-T-P-W-A-V-T-T-T-G-T-S-V-T-I-T-T-R-T-K-D-G-T-Q-V-V-V-T-L-H-L"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-L-K-V-V-K-I-Q-L-P-A-G-K-A-N-P-A-P-P-V-G-T-V-L-G-P-T-G-V-N-I-M-M-V-C-K-E-Y-N-A-L-T-Q-G-Q-A-G-M-I-I-P-A-E-I-T-I-Y-E-D-R-S-F-S-M-K-I-K-T-A-P-V-A-E-L-L-K-R-E-A-G-I-S-K-G-S-G-E-P-N-K-S-K-I-G-S-I-T-E-E-K-L-R-E-I-A-E-Y-K-F-P-D-M-N-A-A-S-V-E-A-A-M-R-T-I-E-G-T-A-R-S-M-G-I-T-V-Q-K"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-M-I-N-E-Q-I-R-A-R-E-V-R-L-V-G-A-N-G-D-Q-L-G-I-K-S-R-N-D-A-L-D-L-A-A-N-L-N-L-D-L-V-L-V-A-P-N-A-K-P-P-V-C-R-I-M-D-Y-G-K-F-R-F-E-Q-Q-K-K-E-K-E-Q-R-K-N-Q-K-V-I-S-M-K-E-V-R-L-S-P-T-I-D-E-H-D-F-N-T-K-L-R-N-A-I-K-F-L-E-K-G-D-K-V-K-A-S-I-R-F-K-G-R-A-I-T-H-K-E-I-G-Q-R-V-L-D-R-F-S-E-A-C-A-E-V-S-T-V-E-S-K-P-K-M-E-G-R-S-M-F-L-V-L-A-P-K-N-D-K"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-L-G-L-D-V-G-T-K-T-V-G-V-A-I-S-D-E-M-G-W-T-A-Q-G-L-E-T-I-K-I-N-E-E-R-G-H-F-G-F-D-R-I-S-E-L-V-K-Q-Y-N-V-D-K-I-V-V-G-L-P-K-N-M-N-G-T-I-G-P-R-G-E-A-C-Q-Q-F-A-E-N-L-R-E-L-L-Q-L-D-V-V-M-W-D-E-R-L-S-T-M-A-A-E-R-L-L-I-S-A-D-V-S-R-K-K-R-K-Q-V-I-D-K-M-A-A-V-V-I-L-Q-G-F-L-D-R-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-L-L-I-D-F-I-D-E-T-E-E-V-K-E-E-Y-M-S-L-I-R-E-V-L-E-K-A-A-Q-M-E-N-I-E-D-G-A-E-V-S-V-T-F-V-D-N-E-R-I-R-E-I-N-R-D-Y-R-D-K-D-Q-P-T-D-V-I-S-F-A-M-E-E-M-G-E-G-E-M-E-I-V-G-A-E-M-P-R-M-L-G-D-L-I-I-S-I-P-R-A-K-E-Q-A-E-E-Y-G-H-S-F-D-R-E-L-G-F-L-A-L-H-G-F-L-H-L-L-G-Y-D-H-M-T-E-E-D-E-K-E-M-F-G-R-Q-K-E-I-L-E-A-F-G-L-G-R"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-V-N-D-F-R-T-G-L-T-I-S-V-D-N-A-L-W-Q-V-L-D-F-Q-H-V-K-P-G-K-G-A-A-F-V-R-S-K-L-R-N-L-R-T-G-S-V-Q-E-K-T-F-R-A-G-E-K-V-E-K-A-H-I-E-N-R-R-M-Q-Y-L-Y-A-S-G-E-A-H-V-F-M-D-N-G-T-Y-E-Q-I-E-L-G-E-K-Q-I-E-R-E-L-K-F-L-K-E-N-M-E-V-A-I-M-T-Y-Q-G-E-V-L-G-V-E-L-P-N-T-V-E-L-Q-V-T-E-T-E-P-G-I-K-G-D-T-A-S-N-V-T-K-P-A-T-L-E-T-G-L-V-V-Q-V-P-I-F-I-N-E-G-E-M-L-I-I-N-T-G-E-G-K-Y-V-S-R-A"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-W-S-K-V-K-Y-F-F-F-D-T-P-E-E-K-E-A-A-Q-Y-G-Y-E-K-E-Q-T-D-M-K-K-Q-Q-D-P-P-E-Q-Q-D-V-T-F-P-K-A-Q-P-K-Q-N-V-V-S-I-E-T-A-K-Q-S-S-K-V-V-L-L-E-P-R-T-Y-S-E-A-Q-G-I-A-D-H-L-K-G-R-R-A-V-V-I-N-L-Q-R-M-S-T-D-Q-A-V-R-I-V-D-F-L-S-G-T-V-Y-A-I-G-G-D-I-Q-K-I-G-P-K-T-F-M-C-T-P-E-N-V-D-I-V-G-A-I-S-E-L-F-G-E-E-E-E-T-N-I-K-R-W"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-G-Q-Q-V-L-K-S-S-N-E-K-M-E-K-A-V-A-A-Y-S-R-E-L-A-T-V-R-A-G-R-A-N-A-S-V-L-D-K-V-Q-V-D-Y-Y-G-A-P-T-P-V-V-Q-L-A-N-I-T-V-P-E-A-R-L-L-V-I-Q-P-Y-D-K-T-S-I-G-D-I-E-K-A-I-L-K-A-D-L-G-L-N-P-S-N-D-G-T-V-I-R-I-A-F-P-A-L-T-E-E-R-R-R-D-L-V-K-V-V-K-K-Y-A-E-E-A-K-V-A-V-R-N-V-R-R-D-G-N-D-D-L-K-K-L-E-K-A-G-E-I-T-E-D-D-L-R-G-Y-T-E-D-I-Q-K-E-T-D-K-Y-I-A-K-V-D-E-I-A-K-N-K-E-K-E-I-M-E-V"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-D-K-K-V-T-E-V-V-E-A-F-A-Q-P-I-V-E-E-L-N-L-E-L-V-D-V-E-Y-V-K-E-G-Q-D-W-F-L-R-V-F-I-D-S-E-K-G-V-D-I-E-E-C-G-A-V-S-E-R-L-S-E-A-L-D-K-E-D-P-I-P-H-L-Y-F-L-D-V-S-S-P-G-A-E-R-P-L-K-K-E-K-D-F-Q-Q-A-V-G-K-Q-V-A-I-K-T-Y-E-P-I-D-G-E-K-M-F-E-G-K-L-L-S-Y-D-G-T-T-I-T-L-L-L-T-I-K-T-R-K-K-E-I-Q-I-S-M-D-K-V-A-N-A-R-L-A-V-T-F"} +{"text": "### FUNCTION Possible metal-dependent hydrolase ### SEQUENCE -M-N-D-L-R-Y-P-I-G-Q-F-T-Y-K-R-P-I-T-E-E-M-I-D-T-W-I-Q-E-I-E-D-L-P-N-E-L-T-K-A-I-K-D-L-D-Q-K-Q-L-D-T-P-Y-R-V-G-G-W-T-V-R-Q-V-V-H-H-V-V-D-S-H-M-N-S-Y-I-R-F-K-L-A-L-T-E-K-N-P-T-I-K-P-Y-K-E-E-K-W-A-E-L-P-D-S-K-L-P-V-D-V-S-L-V-M-L-D-S-L-H-K-R-W-V-N-L-L-Y-S-L-E-I-E-D-L-E-K-T-F-N-H-P-E-T-G-E-T-K-L-A-V-A-I-G-L-Y-A-W-H-G-R-H-H-T-A-H-I-T-S-L-R-K-R-L-N-W"} +{"text": "### FUNCTION Negative regulator of protease production and sporulation ### SEQUENCE -M-K-S-G-E-K-D-Y-S-V-K-E-A-M-I-F-S-Q-R-I-A-Q-L-S-K-A-L-W-K-C-V-E-K-D-W-Q-Q-W-I-K-P-Y-D-L-N-I-N-E-H-H-I-L-T-I-A-Y-H-L-K-G-A-S-I-S-E-I-A-K-F-G-V-M-H-V-S-T-A-F-N-F-S-K-K-L-E-E-R-G-Y-L-V-F-S-K-K-E-D-D-K-R-N-T-Y-I-E-I-T-D-K-G-E-E-L-L-L-R-L-M-E-E-Y-D-P-E-N-N-S-V-F-N-G-A-L-A-L-R-N-F-Y-G-K-F-P-E-N-I-E-L-I-A-I-L-R-N-I-Y-G-Q-D-F-I-D-I-F-E-K-S-L-E-D-I-E-E-N-F-T-E-S-D-Q-K-L-V-K-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-E-V-E-G-T-V-L-E-T-L-P-N-A-M-F-K-V-E-L-E-N-G-H-V-V-L-A-H-V-S-G-K-I-R-M-N-F-I-R-I-L-P-G-D-K-V-T-V-E-L-S-P-Y-D-L-N-R-G-R-I-T-Y-R-F-K"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-R-G-G-M-G-N-M-N-N-M-M-K-Q-M-Q-K-M-Q-K-D-M-A-K-A-Q-E-E-L-G-E-K-T-V-E-G-T-A-G-G-G-M-I-T-V-I-A-N-G-H-K-Q-I-L-E-V-K-I-K-E-E-V-V-D-P-E-D-I-E-M-L-Q-D-L-V-L-A-A-T-N-D-A-L-K-K-A-D-E-L-S-N-S-T-M-G-K-F-T-K-G-L-N-L-P-G-G-M-F"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-S-I-D-M-K-K-K-H-R-I-K-K-N-D-E-F-Q-A-V-F-Q-K-G-K-S-N-A-N-R-Q-F-V-V-Y-Q-L-D-K-E-E-Q-P-N-F-R-I-G-L-S-V-S-K-K-I-G-N-A-V-V-R-N-R-I-K-R-M-V-R-Q-A-I-T-E-L-K-D-E-I-A-S-G-K-D-F-V-I-I-A-R-K-P-C-A-E-M-T-Y-E-E-V-K-K-S-L-I-H-V-F-K-R-S-G-M-K-R-I-K-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-K-Y-E-I-M-Y-I-I-R-P-G-V-E-E-E-A-Q-K-A-L-V-E-R-F-A-G-V-L-T-N-N-G-A-E-I-I-N-T-K-E-W-G-K-R-R-L-A-Y-E-I-N-D-L-R-E-G-F-Y-M-I-L-N-V-K-S-N-A-E-A-I-N-E-F-D-R-L-A-K-I-N-E-D-I-L-R-H-I-V-V-K-E-E-E-K"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-M-N-R-V-I-L-V-G-R-L-T-K-D-P-D-L-R-Y-T-P-N-G-V-A-V-A-T-F-T-L-A-V-N-R-A-F-A-N-Q-Q-G-E-R-E-A-D-F-I-N-C-V-I-W-R-K-Q-A-E-N-V-A-N-Y-L-K-K-G-S-L-A-G-V-D-G-R-L-Q-T-R-N-Y-E-G-Q-D-G-K-R-V-Y-V-T-E-V-L-A-E-S-V-Q-F-L-E-P-R-N-G-G-G-E-Q-R-G-S-F-N-Q-Q-P-S-G-A-G-F-G-N-Q-G-S-N-P-F-G-Q-S-S-N-S-G-N-Q-G-N-S-G-F-T-K-N-D-D-P-F-S-N-V-G-Q-P-I-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-G-R-K-G-G-R-A-K-R-R-K-V-C-F-F-T-A-N-G-I-T-R-I-D-Y-K-D-V-D-L-L-K-R-F-V-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-Y-Q-R-K-L-T-V-A-I-K-R-A-R-Q-M-A-L-L-P-Y-V-G-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-K-D-V-K-G-K-G-K-K-G-E-V-K-N-V-P-D-G-Y-A-N-N-F-L-L-K-Q-G-L-A-A-E-A-T-N-S-S-M-K-T-L-E-A-Q-K-R-K-E-E-K-D-A-A-A-E-L-E-N-A-K-E-L-K-E-T-L-E-K-L-T-V-E-L-K-A-K-S-G-E-G-G-R-L-F-G-S-I-T-S-K-Q-I-V-D-A-M-Q-K-S-H-K-I-K-L-D-K-R-K-F-E-M-D-D-A-I-R-A-L-G-Y-T-N-V-T-V-K-L-H-P-Q-V-T-A-T-V-K-V-H-V-S-E-Q"} +{"text": "### FUNCTION Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA The LrgAB and CidA proteins may affect the proton motive force of the membrane May be involved in programmed cell death , possibly triggering PCD in response to antibiotics and environmental stresses ### SEQUENCE -M-A-K-M-S-T-K-K-V-Y-S-F-L-L-Q-A-F-I-F-S-A-I-M-L-I-S-N-I-I-A-T-H-L-P-I-P-M-P-S-S-V-I-G-L-V-I-L-F-S-L-L-C-L-K-V-I-K-L-E-Q-V-E-S-L-G-T-A-L-T-G-I-I-G-F-L-F-V-P-S-G-I-S-V-I-N-S-L-G-V-M-G-Q-Y-F-V-Q-I-L-T-V-I-V-V-A-T-V-I-L-L-A-V-T-G-L-F-A-Q-F-I-L-G-K-D-E-K-E-T-E-D-I-K-E-L-K-V-V-N-K-G-R-K-H-G-K-V-A"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-D-F-K-Q-Y-S-P-E-E-L-K-E-C-S-M-I-E-V-V-H-S-V-L-G-D-K-K-Q-A-T-T-F-N-E-L-V-Q-E-I-A-Q-V-L-G-L-S-Q-E-Q-V-N-A-K-I-A-Q-F-Y-T-D-L-N-I-D-G-R-F-I-N-L-G-E-N-R-W-G-L-R-S-W-Y-P-Y-E-Q-I-D-E-E-I-L-P-Q-P-K-P-K-K-K-R-K-V-E-E-D-G-F-D-D-Y-I-E-E-D-E-D-D-F-D-D-A-D-V-N-E-D-E-D-D-D-V-E-D-L-D-K-V-L-E-E-E-D-G-D-D-D-D-L-D-D-L-D-E-D-D-D-D-F-A-E-E-E-L-E-Y-D-E-T-E-E-E-E-E-E-E-L"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-T-F-E-Q-L-I-P-L-I-I-M-A-F-A-L-G-M-D-A-F-S-V-S-L-G-M-G-M-M-P-L-K-L-R-Q-I-L-Y-I-G-M-T-I-G-I-F-H-I-I-M-P-F-I-G-M-V-L-G-R-F-L-S-E-K-Y-G-D-I-A-H-F-A-G-A-I-L-L-I-G-L-G-F-Y-I-V-Y-S-T-I-L-Q-N-E-E-T-R-T-A-P-I-G-I-S-L-F-V-F-A-F-G-V-S-I-D-S-F-S-V-G-L-S-L-G-I-Y-G-A-Q-T-I-I-T-I-L-L-F-G-F-V-S-M-L-L-A-W-I-G-L-L-I-G-R-H-A-K-D-M-L-G-T-Y-G-E-I-V-G-G-I-I-L-V-G-F-G-L-Y-I-L-F-P-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-P-T-L-L-L-G-A-S-I-P-F-G-T-I-A-Y-T-L-F-I-F-L-L-L-L-V-M-L-R-K-F-A-W-G-P-L-M-G-I-M-K-E-R-E-E-H-V-A-N-E-I-D-A-A-E-R-N-N-A-E-A-K-K-L-V-E-E-Q-R-E-M-L-K-Q-S-R-V-E-A-Q-E-L-I-E-R-A-K-K-Q-A-V-D-Q-K-D-V-I-V-A-A-A-K-E-E-A-E-S-I-K-A-S-A-V-Q-E-I-Q-R-E-K-E-Q-A-I-A-A-L-Q-E-Q-V-A-S-L-S-V-Q-I-A-S-K-V-I-E-K-E-L-K-E-E-D-Q-V-K-L-I-R-D-Y-I-K-E-V-G-E-A-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-N-G-I-V-A-K-R-Y-A-V-A-L-F-K-I-A-K-E-K-H-V-L-E-M-F-E-E-E-L-R-L-V-Q-N-V-Y-V-K-N-G-E-L-H-S-F-L-T-Q-P-N-I-S-K-E-Q-K-K-T-F-L-A-N-V-F-G-S-V-S-E-S-I-L-N-T-L-Y-I-L-I-D-N-K-R-I-D-I-L-P-E-I-A-D-E-Y-V-V-L-A-N-E-E-R-N-V-A-D-A-T-V-Y-S-T-R-L-L-S-E-E-E-K-L-N-I-A-E-A-F-A-K-R-T-G-K-D-A-I-R-V-K-N-V-V-D-E-D-L-L-G-G-I-K-V-R-I-G-N-R-I-Y-D-G-S-L-Q-G-K-L-A-R-I-Q-R-E-L-M-K-N-R"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-P-K-G-T-G-K-V-I-A-Q-N-K-K-A-F-H-D-Y-F-I-E-E-T-Y-E-A-G-L-V-L-Q-G-T-E-I-K-S-I-R-A-G-R-V-N-L-K-D-A-F-A-R-V-H-N-G-E-V-W-V-H-N-M-H-I-N-T-Y-E-Q-G-N-R-F-N-H-D-P-L-R-T-R-K-L-L-L-H-K-K-E-I-D-K-L-A-G-A-A-K-E-T-G-Y-A-L-V-P-L-R-I-Y-L-K-N-G-F-A-K-M-A-L-G-L-A-K-G-K-K-Q-Y-D-K-R-H-D-L-K-E-K-E-A-K-R-E-I-A-R-A-F-R-D-R-Q-K-M"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-E-A-L-L-V-A-T-G-G-F-F-G-A-I-T-R-F-A-I-S-N-W-F-K-K-R-N-K-T-Q-F-P-L-A-T-F-L-I-N-I-T-G-A-F-L-L-G-Y-I-I-G-N-G-V-T-T-G-W-Q-L-L-L-G-T-G-F-M-G-A-F-T-T-F-S-T-F-K-L-E-A-V-Q-L-L-N-R-K-N-I-S-T-F-L-L-Y-L-S-A-T-Y-I-I-G-I-L-F-A-F-L-G-M-K-L-G-G-I"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-S-N-L-F-K-E-V-R-K-L-I-Y-I-I-V-G-I-A-G-I-L-G-A-L-S-R-Y-Y-L-G-L-N-I-T-T-F-W-H-H-S-F-P-L-A-T-L-L-I-N-L-I-G-C-F-F-L-A-W-L-T-T-Y-I-A-R-L-N-I-L-P-S-E-V-I-T-G-I-G-T-G-F-I-G-S-F-T-T-F-S-T-F-S-V-E-T-V-Q-L-I-N-H-S-E-W-S-I-A-F-L-Y-V-S-C-S-I-L-G-G-L-I-M-S-G-L-G-Y-T-L-G-D-F-L-I-K-K-S-L-T-E-G-D-Y-S"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-S-V-E-S-F-E-L-D-H-T-I-V-K-A-P-Y-V-R-H-C-G-V-H-N-V-G-S-D-G-I-V-N-K-F-D-I-R-F-C-Q-P-N-K-Q-A-M-K-P-D-V-I-H-T-L-E-H-L-L-A-F-N-L-R-K-Y-I-D-R-Y-P-H-F-D-I-I-D-I-S-P-M-G-C-Q-T-G-Y-Y-L-V-V-S-G-T-P-T-V-R-E-I-I-D-L-L-E-L-T-L-K-D-A-V-Q-I-T-E-I-P-A-A-N-E-T-Q-C-G-Q-A-K-L-H-D-L-E-G-A-Q-R-L-M-N-F-W-L-S-Q-D-K-D-E-L-E-K-V-F-G"} +{"text": "### FUNCTION May be involved in the biosynthesis of molybdopterin ### SEQUENCE -M-S-V-T-E-H-K-K-Q-A-P-K-E-V-R-C-K-I-V-T-I-S-D-T-R-T-E-E-T-D-K-S-G-Q-L-L-H-E-L-L-K-E-A-G-H-K-V-T-S-Y-E-I-V-K-D-D-K-E-S-I-Q-Q-A-V-L-A-G-Y-H-K-E-D-V-D-V-V-L-T-N-G-G-T-G-I-T-K-R-D-V-T-I-E-A-V-S-A-L-L-D-K-E-I-V-G-F-G-E-L-F-R-M-I-S-Y-L-E-D-I-G-S-S-A-M-L-S-R-A-I-G-G-T-I-G-R-K-V-V-F-S-M-P-G-S-S-G-A-V-R-L-A-M-N-K-L-I-L-P-E-L-G-H-I-T-F-E-L-H-R-Q"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-W-N-E-F-K-K-F-A-F-K-G-N-V-V-D-L-A-V-G-V-V-I-G-A-A-F-G-K-I-V-S-S-L-V-K-D-I-I-T-P-L-L-G-M-V-L-G-G-V-D-F-T-S-L-H-F-G-Y-G-K-S-A-V-M-Y-G-N-F-I-Q-T-I-F-D-F-L-I-I-A-A-S-I-F-M-F-V-K-V-F-N-K-L-T-S-K-K-E-E-E-K-E-E-E-I-P-E-P-T-K-E-E-E-L-L-G-E-I-R-D-L-L-K-Q-Q-N-S-S-K-D-R-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-R-Y-T-G-P-A-W-K-L-S-R-R-L-G-I-S-L-S-G-T-G-K-E-L-E-K-R-P-Y-A-P-G-P-H-G-P-N-Q-R-K-K-L-S-E-Y-G-L-Q-L-Q-E-K-Q-K-L-R-H-M-Y-G-M-T-E-R-Q-F-R-R-T-F-D-Q-A-G-K-M-P-G-K-H-G-E-N-F-M-I-L-L-E-A-R-L-D-N-L-V-Y-R-M-G-L-A-R-T-R-R-A-A-R-Q-L-V-N-H-G-H-I-M-V-D-G-A-R-V-D-I-P-S-Y-R-V-K-P-G-Q-T-I-S-V-R-E-K-S-N-S-L-V-V-V-K-E-A-I-E-V-N-N-F-V-P-E-Y-L-T-F-D-A-D-K-L-E-A-T-Y-T-R-H-A-E-R-S-E-L-P-A-E-I-N-E-A-L-I-V-E-F-Y-S-R"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-S-C-S-H-N-G-T-R-V-L-D-S-R-P-V-D-E-G-R-S-I-R-R-R-R-E-C-E-S-C-L-S-R-F-T-T-F-E-R-V-E-E-S-P-L-I-V-V-K-K-E-G-T-R-E-E-F-N-K-E-K-I-L-R-G-L-I-K-A-C-E-K-R-P-V-S-L-R-Q-L-E-E-V-T-Q-S-V-E-R-E-L-R-N-L-G-I-S-E-V-K-S-D-M-I-G-E-I-V-M-E-E-L-R-D-I-D-D-V-A-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-L-N-V-F-I-E-E-L-K-D-I-L-Q-K-E-R-E"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-G-G-T-V-T-R-Q-R-R-K-K-V-I-K-L-A-K-G-Y-Y-G-S-K-N-T-L-F-K-V-A-N-Q-Q-V-M-K-S-L-M-Y-A-F-R-D-R-R-Q-K-K-R-D-F-R-K-L-W-I-T-R-I-N-A-A-A-R-M-N-G-L-S-Y-S-R-L-M-H-G-L-K-N-A-G-I-E-V-N-R-K-M-L-A-D-L-A-V-H-D-E-K-A-F-A-E-L-A-T-V-A-K-N-N-I-N"} +{"text": "### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-S-Q-Q-K-G-K-K-S-R-I-N-V-E-I-Y-G-Q-Q-Y-S-V-V-G-D-E-S-T-S-H-I-R-M-V-A-A-I-V-D-D-K-M-R-E-L-N-A-K-N-P-S-L-D-T-S-R-L-A-V-L-T-A-V-N-V-I-H-D-Y-I-K-L-K-E-E-H-E-K-L-K-E-S-M-T-K-K-G-M-E"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-K-V-T-K-A-D-I-V-I-S-A-V-K-P-E-Q-Y-P-D-S-D-L-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-K-I-L-N-R-K-K-L-V-R-I-S-S-K-P-G-K-T-Q-T-L-N-F-F-L-I-N-E-M-M-H-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-S-E-R-A-A-W-G-K-M-I-E-T-Y-F-T-T-R-E-Q-L-D-A-A-V-L-V-V-D-L-R-H-Q-P-T-S-D-D-V-M-M-Y-D-F-L-K-H-Y-E-I-P-T-I-I-I-A-T-K-A-D-K-I-P-K-G-K-W-Q-K-H-L-K-V-V-K-E-T-L-A-V-E-I-G-D-E-I-V-L-F-S-S-E-T-G-L-G-K-E-E-A-W-K-A-I-H-K-F-T-K-T-K-N-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-E-T-G-G-K-Q-I-K-V-E-A-G-Q-A-I-Y-I-E-K-L-D-V-E-A-G-E-T-V-T-F-D-K-V-L-F-V-G-G-E-N-V-K-V-G-S-P-V-V-E-G-A-T-V-T-A-K-V-E-K-Q-G-R-A-K-K-I-I-V-F-K-Y-K-A-K-K-N-N-R-K-K-Q-G-H-R-Q-P-Y-T-K-L-V-V-E-A-I-N-A"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-F-K-Q-H-I-A-I-V-P-D-Y-P-K-E-G-I-V-F-K-D-I-T-P-L-M-N-D-G-K-A-Y-K-A-A-T-D-A-I-V-E-Y-A-K-E-R-D-I-D-V-V-V-G-P-E-A-R-G-F-I-I-G-C-P-V-S-Y-A-L-E-V-G-F-A-P-V-R-K-L-G-K-L-P-R-E-V-I-T-V-D-Y-G-K-E-Y-G-K-D-V-L-T-I-H-K-D-A-I-K-P-G-Q-R-V-L-I-T-D-D-L-L-A-T-G-G-T-I-E-A-T-I-K-L-V-E-E-L-G-G-V-V-A-G-I-A-F-L-V-E-L-T-Y-L-D-G-R-K-M-L-D-G-Y-D-V-L-V-L-E-K-Y"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-T-E-K-T-Y-P-M-T-Q-E-G-K-Q-K-L-E-N-E-L-E-Q-L-K-T-V-R-R-K-E-V-V-E-R-I-K-I-A-R-S-F-G-D-L-S-E-N-S-E-Y-D-A-A-K-D-E-Q-A-F-V-E-G-R-I-T-Q-L-E-N-M-I-R-N-A-V-I-I-K-D-T-G-E-V-S-T-V-V-T-L-G-K-T-V-T-F-K-E-L-P-N-G-D-E-E-A-Y-T-I-V-G-S-A-E-A-D-P-F-E-G-R-I-S-N-D-S-P-I-A-K-S-L-L-G-K-Q-I-G-E-K-V-T-I-Q-T-P-G-G-E-M-Q-V-E-I-V-S-V-K"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-R-K-I-G-I-I-G-G-T-F-D-P-P-H-Y-G-H-L-L-I-A-N-E-V-Y-H-A-L-N-L-E-E-V-W-F-L-P-N-Q-I-P-P-H-K-Q-G-R-N-I-T-S-V-E-S-R-L-H-M-L-E-L-A-T-E-A-E-E-H-F-S-I-C-L-E-E-L-S-R-K-G-P-S-Y-T-Y-D-T-M-L-Q-L-T-K-K-Y-P-D-V-Q-F-H-F-I-I-G-G-D-M-V-E-Y-L-P-K-W-Y-N-I-E-A-L-L-N-L-V-T-F-V-G-V-A-R-P-G-Y-T-L-H-T-P-Y-K-I-T-T-V-E-I-P-E-F-A-V-S-S-S-L-L-R-E-R-Y-K-E-K-K-T-C-K-Y-L-L-P-E-K-V-Q-V-Y-I-E-R-N-G-L-Y-E-S"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-A-K-L-S-E-E-R-R-A-H-N-A-S-I-K-S-D-M-R-S-A-V-K-T-V-E-A-L-V-T-N-N-D-L-E-N-A-K-E-A-F-K-T-A-S-K-K-L-D-K-A-A-R-K-G-L-I-H-Q-N-A-A-A-R-Q-K-S-R-L-A-K-Q-V-N-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-E-E-R-N-E-Q-V-V-E-E-V-K-E-A-Q-V-E-E-A-V-T-P-E-N-S-E-E-T-V-E-E-K-S-E-A-A-L-L-Q-E-K-V-D-E-L-Q-A-K-L-T-E-T-E-G-R-T-L-R-L-Q-A-D-F-E-N-Y-K-R-R-V-Q-M-D-K-Q-A-A-E-K-Y-R-A-Q-S-L-V-S-D-I-L-P-A-L-D-N-F-E-R-A-M-Q-V-E-A-T-D-E-Q-T-K-S-L-L-Q-G-M-E-M-V-H-R-Q-L-L-E-A-L-T-K-E-G-V-E-V-I-E-A-V-G-K-Q-F-D-P-N-E-H-Q-A-I-M-Q-V-E-D-S-E-F-E-S-N-A-V-V-E-E-F-Q-K-G-Y-K-L-K-D-R-V-I-R-P-S-M-V-K-V-N-Q"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-R-R-T-A-R-E-R-A-M-Q-A-L-Y-Q-M-D-I-T-G-E-L-E-P-K-V-A-V-E-N-T-L-D-E-G-E-E-T-N-E-F-L-E-S-L-V-V-G-F-V-E-N-K-E-A-I-D-E-A-I-R-Q-N-L-K-K-W-K-L-E-R-I-S-I-V-D-R-S-I-L-R-V-A-V-Y-E-M-K-Y-M-E-E-I-P-H-N-V-T-I-N-E-A-I-E-I-A-K-T-F-G-D-E-E-S-R-R-F-I-N-G-V-L-S-N-I-K-D-T-L"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-E-N-K-L-S-F-E-E-A-I-S-Q-L-E-H-L-V-S-K-L-E-Q-G-D-V-P-L-E-E-A-I-S-Y-F-K-E-G-M-E-L-S-K-L-C-D-E-K-L-K-N-V-Q-E-Q-M-A-V-I-L-G-E-D-G-E-L-E-P-F-T-A-L-G-D-E-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-G-Q-R-H-I-K-I-R-E-I-I-A-N-K-E-I-E-T-Q-D-E-L-V-D-I-L-R-N-E-G-F-N-V-T-Q-A-T-V-S-R-D-I-K-E-L-H-L-V-K-V-P-L-H-D-G-R-Y-K-Y-S-L-P-A-D-Q-R-F-N-P-L-Q-K-L-K-R-N-L-V-D-S-F-V-K-L-D-T-A-G-H-M-L-V-L-K-T-L-P-G-N-A-H-S-L-G-A-L-I-D-H-L-E-W-D-E-I-I-G-T-I-C-G-D-D-T-C-L-I-I-C-R-T-P-D-D-T-G-V-V-S-D-R-F-L-N-M-L"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-D-R-K-E-Q-K-S-I-I-E-G-L-L-F-V-S-G-D-E-G-I-Y-P-E-Q-I-A-K-V-L-E-I-E-M-N-E-A-I-N-I-L-E-E-M-Q-Q-E-C-E-G-A-N-R-G-L-Q-I-V-Q-Y-A-K-V-Y-R-F-A-T-K-K-E-H-A-S-Y-Y-Q-K-L-I-D-T-P-T-A-A-S-L-S-Q-A-A-L-E-T-L-A-I-V-A-Y-R-Q-P-I-T-R-T-E-M-E-E-I-R-G-V-K-T-D-K-A-L-Q-T-L-V-S-H-L-L-I-K-E-M-G-R-A-E-G-P-G-R-P-I-L-Y-G-T-T-K-E-F-L-D-T-F-G-L-K-T-L-D-D-L-P-P-L-S-E-E-N-E-Q-M-N-E-A-D-L-F-F-G-C-L-Q-E-I-W-K"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-F-K-V-F-Y-Q-E-K-L-T-E-V-P-V-R-E-N-T-K-V-L-Y-L-E-A-T-S-E-K-D-V-R-T-K-L-N-K-F-A-Y-N-I-E-F-V-Q-S-V-T-G-A-H-L-E-Y-E-K-E-N-A-D-L-T-L-A-E-I-V"} +{"text": "### FUNCTION Essential cell division protein ### SEQUENCE -M-T-N-L-A-V-K-Y-K-Q-Q-A-Q-E-E-V-Q-I-Q-T-P-P-Q-Q-M-A-K-P-K-V-K-A-K-I-T-R-I-E-K-L-L-Y-V-A-F-I-G-F-L-L-Y-A-C-V-A-F-I-G-N-K-A-G-L-Y-Q-V-N-V-E-A-A-T-I-E-E-K-I-V-Q-Q-Q-K-E-N-Q-E-L-Q-A-E-V-E-K-L-S-R-Y-E-R-I-A-E-V-A-K-K-H-G-L-E-I-N-A-N-N-V-K-G-L-K"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-Q-E-K-A-V-V-L-D-D-Q-M-I-R-R-A-L-T-R-I-S-H-E-I-V-E-R-N-K-G-V-D-N-C-V-L-V-G-I-K-T-R-G-I-F-I-A-Q-R-L-A-E-R-I-G-Q-I-E-G-K-E-M-E-V-G-E-L-D-I-T-L-Y-R-D-D-L-T-L-Q-S-K-N-K-E-P-L-V-K-G-S-D-I-P-V-D-I-T-K-K-K-V-I-L-V-D-D-V-L-Y-T-G-R-T-V-R-A-A-M-D-A-L-M-D-L-G-R-P-S-Q-I-Q-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-S-E-E-R-I-E-V-D-L-Q-E-T-D-Q-Q-D-R-V-S-I-Y-D-K"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-L-N-P-S-I-D-S-L-L-Q-K-I-D-S-K-Y-T-L-V-T-V-A-A-K-R-A-R-E-M-Q-L-A-N-N-C-V-V-E-K-P-V-S-H-K-C-V-G-K-A-L-E-E-I-D-A-E-A-L-S-Y-V-P-S-E-D-K-V-A-E"} +{"text": "### FUNCTION Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism ### SEQUENCE -M-K-K-R-R-S-K-K-E-R-Q-E-L-L-Q-Q-T-I-E-S-N-P-F-I-T-D-E-D-L-A-E-K-F-Q-V-S-I-Q-T-V-R-L-D-R-M-E-L-S-I-P-E-L-R-E-R-I-K-H-V-A-T-K-Q-H-E-E-D-V-K-S-L-P-L-E-E-V-V-G-E-I-I-D-I-E-L-D-R-H-A-I-S-I-F-E-V-K-I-E-H-V-F-K-R-N-Q-I-A-R-G-H-H-L-F-A-Q-A-N-S-L-A-V-A-V-I-D-E-E-L-A-L-T-A-K-S-T-I-R-Y-I-R-P-V-K-L-G-E-R-V-V-A-K-A-R-V-E-D-V-E-N-D-K-G-R-T-V-V-K-V-R-S-F-V-G-E-E-L-V-F-T-G-T-F-E-M-Y-R-S-S-N-Y-S-E-E-G-N-N-L"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-D-V-L-E-R-V-T-K-I-I-V-D-R-L-G-V-E-E-T-E-V-V-P-A-A-S-F-K-E-D-L-G-A-D-S-L-D-V-V-E-L-V-M-Q-L-E-D-E-F-E-M-E-I-S-D-E-D-A-E-K-I-A-T-V-G-D-A-V-T-Y-I-E-S-H-L"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-K-W-F-N-V-G-K-I-V-N-T-H-G-V-R-G-E-I-R-V-I-S-R-T-D-F-P-E-E-R-Y-K-V-G-N-T-L-Y-I-S-N-E-K-G-T-D-Y-L-P-V-K-V-T-S-H-R-Q-H-K-T-F-D-L-L-T-F-E-G-Y-N-N-V-D-E-V-E-K-F-K-G-S-L-I-K-V-P-E-E-Q-L-G-E-L-A-E-G-E-Y-Y-Y-H-E-I-I-G-C-S-V-V-T-E-E-G-E-A-L-G-T-I-K-E-I-L-S-P-G-A-N-D-V-W-V-I-K-R-P-K-G-Q-D-L-L-I-P-Y-I-D-D-V-V-L-Q-V-N-I-E-N-K-L-V-T-I-H-V-M-E-G-L-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-Q-Q-L-I-A-E-I-T-K-G-Q-L-K-T-D-L-P-S-F-R-P-G-D-T-L-R-V-H-V-K-V-V-E-G-T-R-E-R-I-Q-L-F-E-G-V-V-I-K-R-R-G-G-G-I-S-E-T-F-T-V-R-K-I-S-Y-G-V-G-V-E-R-T-F-P-V-H-T-P-R-I-A-K-I-E-V-L-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-N-L-R-G-K-K-A-R-I-K-E-I-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-L-R-A-N-R-V-G-E-Q-M-K-K-E-L-G-D-I-I-S-R-K-I-K-D-P-R-I-G-F-V-T-V-T-D-V-Q-V-S-G-D-L-Q-I-A-K-V-Y-I-S-V-L-G-D-E-E-Q-K-E-N-T-L-K-G-L-A-K-A-K-G-F-I-R-S-E-I-G-Q-R-I-R-L-R-K-T-P-E-I-T-F-E-F-D-E-S-I-G-Y-G-H-R-I-D-T-L-L-H-E-I-N-K-D-G-K-R-E-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-Q-E-R-K-N-E-I-I-A-Q-F-R-T-H-E-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-E-Q-I-N-T-L-N-E-H-L-R-T-H-K-K-D-H-H-S-R-R-G-L-L-K-M-V-G-K-R-R-N-L-L-T-Y-L-R-N-S-D-I-T-R-Y-R-E-L-I-T-K-L-G-L-R-R"} +{"text": "### FUNCTION Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation Inhibited by the antiholin-like proteins LrgAB In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential ### SEQUENCE -M-K-Y-V-T-L-L-L-Q-V-G-V-L-Y-V-F-S-L-V-G-T-W-I-Q-G-V-F-H-L-S-M-P-G-S-L-I-G-M-L-I-L-F-L-L-L-S-T-R-V-L-P-L-K-W-F-E-L-G-A-E-K-L-I-V-F-L-P-L-F-L-I-P-S-T-T-G-L-M-E-Y-G-S-F-L-F-S-K-E-S-I-I-F-L-L-V-V-A-S-T-V-V-T-L-I-V-S-G-Y-I-S-Q-L-L-I-T-T-K-K"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-K-Q-S-I-N-I-Q-D-Q-F-L-N-Q-L-R-K-E-N-T-F-V-T-L-Y-L-L-N-G-F-Q-L-R-G-L-I-K-G-F-D-N-F-T-V-L-L-E-T-E-G-K-Q-Q-L-I-Y-K-H-A-I-S-T-F-V-P-Q-K-N-V-S-I-E-L-E"} +{"text": "### FUNCTION Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation Inhibited by the antiholin-like proteins LrgAB In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential ### SEQUENCE -M-K-W-W-K-L-S-G-Q-I-L-L-L-F-C-F-A-W-T-G-E-W-I-A-K-Q-A-H-L-P-V-P-G-S-I-I-G-I-F-L-L-L-I-S-L-K-F-N-L-V-K-K-E-W-I-Q-D-G-A-D-F-L-L-K-E-L-I-L-F-F-I-P-S-A-V-A-V-I-R-Y-R-D-T-L-T-Q-Y-G-I-D-L-I-L-I-I-M-I-S-T-L-C-V-T-L-V-T-G-L-L-T-E-L-L-L-K-R-K-G-S-T-Q"} +{"text": "### FUNCTION Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization ### SEQUENCE -M-L-L-Q-G-T-H-R-I-G-R-M-A-M-L-L-A-L-A-D-E-N-E-S-P-V-L-S-I-P-K-G-W-K-Y-C-T-G-K-V-G-S-M-N-S-Q-K-V-V-A-A-M-E-T-A-A-K-S-N-Q-V-I-E-T-D-V-Y-R-E-T-H-A-L-Y-H-A-I-M-E-A-L-Y-G-V-T-R-G-Q-I-Q-L-A-D-V-L-R-T-V-G-L-R-F-A-I-V-R-G-T-P-Y-D-G-K-K-E-G-E-W-V-A-V-A-L-Y-G-T-I-G-A-P-V-K-G-S-E-H-E-A-I-G-L-G-I-N-H-I"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-I-L-Y-T-T-A-S-C-A-S-C-R-K-A-K-A-W-L-E-E-H-Q-I-D-Y-I-E-K-N-I-V-S-N-S-M-T-V-D-E-L-K-S-I-L-R-L-T-E-E-G-A-T-E-I-I-S-T-R-S-K-T-F-Q-D-L-N-I-N-I-D-E-L-S-L-N-E-F-Y-T-L-I-I-E-H-P-L-M-L-R-R-P-I-M-L-D-E-K-R-L-Q-I-G-F-N-E-E-E-I-R-K-F-L-P-R-S-V-R-T-F-L-N-I-E-L-Q-K-L-A-N"} +{"text": "### FUNCTION Catalyzes the reduction of arsenate ### SEQUENCE -M-E-N-K-K-T-I-Y-F-L-C-T-G-N-S-C-R-S-Q-M-A-E-A-W-G-K-Q-Y-L-G-D-K-W-N-V-Y-S-A-G-M-E-A-H-G-V-N-P-N-A-I-K-A-M-N-E-V-N-I-D-I-T-N-Q-T-S-D-I-I-D-A-N-I-L-N-S-A-D-L-V-V-T-L-C-S-H-A-D-S-V-C-P-S-T-P-P-H-V-N-R-V-H-W-G-F-D-D-P-A-G-K-E-W-S-E-F-Q-R-V-R-D-E-I-G-E-R-I-K-R-F-S-K-T-G-E"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Antitoxin that binds toxin SpoIISA and neutralizes its toxic activity Upon coexpression with SpoIISA in Ecoli normal growth is restored ### SEQUENCE -M-A-E-V-N-V-Q-K-S-S-F-F-K-E-K-K-E-E-S-N-T-D-F-S-L-V-K-G-A-L-T-E-N-I-N-R-L-E-K-L-M-N-N-S-S-S-K-Y-I-Q-V-K-R-T-K-E-N-A"} +{"text": "### FUNCTION Can bind to ATTGG and CCAAT motifs of single-stranded oligonucleotides ### SEQUENCE -M-T-L-T-G-K-V-K-W-F-N-S-E-K-G-F-G-F-I-E-V-A-D-G-N-D-V-F-V-H-F-S-A-I-T-G-D-G-F-K-S-L-D-E-G-Q-E-V-S-F-E-V-E-E-G-N-R-G-P-Q-A-K-N-V-V-K-L"} +{"text": "### FUNCTION Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure ### SEQUENCE -M-E-Y-K-T-P-F-I-A-K-K-L-G-V-S-P-K-A-V-V-R-I-A-Q-Q-L-N-L-T-I-E-K-N-K-Y-G-H-F-I-F-T-Q-E-D-V-D-Q-M-L-E-H-H-R-F-Q-I-E-Q-S-Q-N-S-Q-S-T-Q-K-A-S-S-N-E-V-E-E-L-K-T-Q-V-N-T-I-V-Q-N-I-S-S-N-D-F-E-Q-L-A-N-Q-L-N-T-I-T-R-R-L-D-R-M-E-E-Q-M-Q-D-K-A-N-D-V-V-T-Y-Q-L-L-Q-H-R-R-E-M-E-E-M-L-E-R-I-Q-K-L-E-A-A-L-T-K-E-E-P-I-Y-I-T-P-D-S-K-P-T-Y-E-R-E-K-K-P-K-R-R-K-M-I-F-S-I-F-G-L"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-F-S-N-I-G-F-P-G-L-I-L-I-L-V-A-V-L-I-L-F-G-P-K-K-L-P-E-I-G-K-A-L-G-E-T-L-K-E-F-K-K-S-T-K-E-L-T-D-D-A-F-Q-E-K-E-K-K-E-K-M"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-I-S-D-K-I-K-L-T-A-K-D-I-L-E-K-E-F-K-T-G-M-R-G-Y-Q-Q-E-E-V-D-K-F-L-D-M-I-I-K-D-Y-E-A-F-H-K-E-F-E-Q-L-K-Q-Q-N-A-R-L-K-R-E-L-E-E-Q-K-L-A-V-T-Q-V-P-Q-Q-P-V-Q-T-P-V-A-Q-P-V-Y-N-N-T-N-T-D-I-L-K-R-L-S-N-L-E-K-A-V-F-G-S-K-L-Y-E"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-K-I-A-L-I-A-H-D-K-K-K-N-D-M-V-S-F-A-Y-A-Y-K-P-I-F-E-Q-H-E-L-F-A-T-G-T-T-G-L-R-I-M-E-A-T-G-L-V-I-T-R-Y-Q-S-G-P-L-G-G-D-Q-E-I-G-A-M-I-A-K-N-D-L-D-M-V-I-F-F-R-D-P-L-T-A-Q-P-H-E-P-D-V-N-A-L-L-R-L-C-D-V-Y-A-I-P-L-A-T-N-M-A-S-A-E-M-L-M-H-A-L-E-R-G-D-L-D-Y-R-K-L-R-K"} +{"text": "### FUNCTION Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c ### SEQUENCE -M-K-K-N-R-L-L-F-R-V-I-I-L-L-I-L-C-G-A-V-G-F-T-L-Y-Q-G-F-F-A-N-K-E-K-M-Q-I-G-K-E-A-P-N-F-I-V-T-D-L-E-G-K-K-I-E-L-K-D-L-K-G-K-G-V-F-L-N-F-W-G-T-W-C-K-P-C-E-K-E-M-P-Y-M-N-E-L-Y-P-K-Y-K-E-K-G-V-E-I-I-A-L-D-A-D-E-T-D-I-A-V-K-N-F-V-N-Q-Y-G-L-K-F-P-V-A-I-D-K-G-Q-K-I-I-G-T-Y-G-V-G-P-L-P-T-S-F-L-I-D-K-D-G-K-V-V-E-Q-I-I-G-E-Q-T-K-E-Q-L-E-G-Y-L-K-K-I-T-P"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-M-E-P-F-R-I-H-K-G-T-A-A-V-L-M-N-D-N-I-D-T-D-Q-I-I-P-K-Q-Y-L-K-R-I-E-R-T-G-F-G-K-F-L-F-D-E-W-R-Y-D-N-N-R-Q-E-N-P-N-F-P-L-N-A-Q-E-R-K-G-A-S-I-L-I-T-G-D-N-F-G-C-G-S-S-R-E-H-A-P-W-A-L-A-D-Y-G-F-R-V-I-I-A-G-G-F-A-D-I-F-Y-M-N-C-M-K-N-G-M-L-P-I-V-M-D-K-D-M-R-E-Q-L-A-K-T-D-A-R-E-Q-I-T-V-D-L-E-N-E-I-M-T-T-N-T-H-R-F-H-F-T-I-E-K-M-W-K-E-K-L-L-N-G-L-D-E-I-S-I-T-M-Q-Y-E-Q-E-I-K-E-Y-E-R-K-V-A-L-H"} +{"text": "### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-A-E-F-K-E-Q-V-L-D-I-L-E-E-V-C-E-N-D-I-V-K-E-N-L-D-V-Q-L-F-E-E-G-I-L-D-S-F-A-V-V-S-L-L-V-E-F-Q-E-R-L-D-I-E-V-S-I-S-D-F-D-R-D-E-W-A-T-P-N-M-V-I-K-K-L-E-E-I-R"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-T-L-Y-S-S-P-S-C-T-S-C-R-K-A-K-L-W-L-E-E-N-H-I-P-Y-T-E-R-N-I-F-S-D-P-L-T-I-E-E-I-K-E-I-L-R-M-T-E-S-G-T-D-E-I-I-S-T-R-S-K-V-F-Q-E-L-N-V-N-L-E-S-L-P-L-Q-D-L-Y-K-M-I-R-D-Y-P-G-I-L-R-R-P-I-M-I-D-E-K-R-L-Q-V-G-Y-N-E-D-E-I-R-R-F-L-P-R-T-V-R-T-F-Q-L-R-E-A-Q-R-L-V-N"} +{"text": "### FUNCTION Can bind to ATTGG and CCAAT motifs of single-stranded oligonucleotides ### SEQUENCE -M-A-V-T-G-Q-V-K-W-F-N-N-E-K-G-F-G-F-I-E-V-P-G-E-N-D-V-F-V-H-F-S-A-I-E-T-D-G-F-K-S-L-E-E-G-Q-K-V-S-F-E-I-E-E-G-N-R-G-P-Q-A-K-N-V-I-K-L"} +{"text": "### FUNCTION Negative regulator of sigma-B activity Phosphorylates and inactivates its specific antagonist protein, RsbV Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme ### SEQUENCE -M-M-E-R-F-E-K-I-E-M-K-I-P-A-K-A-E-Y-V-A-I-I-R-L-T-M-A-G-V-A-N-R-M-G-F-A-Y-D-D-I-E-D-M-K-I-A-I-S-E-A-C-T-N-I-V-Q-H-A-Y-K-E-D-V-G-E-I-A-I-V-F-G-L-Y-E-N-R-L-E-I-M-V-A-D-N-G-V-S-F-D-F-N-N-L-K-R-K-V-G-P-Y-D-I-S-K-P-V-E-H-L-P-E-N-G-L-G-L-Y-L-I-N-T-L-M-D-D-I-Q-I-M-H-D-E-G-M-T-V-L-M-T-K-Y-I-Q-R-E-Q-V-E-N-D-G-N-P-I-S-T-Y-E-S-Y"} +{"text": "### FUNCTION Immunity component of an LXG toxin-immunity module Neutralizes the RNase activity of cognate toxin BC_0920 Probably does not have immunity protein activity on other toxins with the LXG domain ### SEQUENCE -M-K-Y-P-Y-S-F-E-V-L-T-N-G-K-L-V-M-R-L-P-Q-E-I-K-L-M-E-T-F-L-G-V-E-V-S-A-F-G-D-W-I-L-E-E-I-H-S-V-L-N-G-K-E-N-Y-V-V-V-N-G-N-I-C-G-L-E-I-R-K-D-T-T-T-V-L-D-N-L-A-E-D-G-K-G-D-F-C-E-I-E-T-I-E-L-V-D-L-I-H-I-W-Q-D-K-Q-K-E-F-K-K-G-K-N-K-E-L-K"} +{"text": "### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-G-R-E-K-K-Q-E-Y-A-L-L-T-A-W-G-A-S-F-I-A-T-L-G-S-L-Y-F-S-E-I-M-K-F-E-P-C-V-L-C-W-Y-Q-R-I-F-M-Y-P-F-V-L-W-L-G-I-A-V-A-K-K-D-Y-R-I-A-S-Y-S-L-P-I-A-S-I-G-A-C-I-S-L-Y-H-Y-A-I-Q-K-V-A-A-F-S-A-A-G-A-A-C-G-R-V-P-C-T-G-E-Y-I-N-W-F-G-F-V-T-I-P-F-L-A-L-I-G-F-I-T-I-A-V-C-S-F-I-V-I-K-N-K"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-E-K-K-Q-S-I-L-S-P-I-I-R-I-T-F-T-F-L-V-L-C-G-L-V-Y-P-L-I-V-T-G-I-A-Q-A-V-M-K-D-N-A-D-G-S-L-I-Y-N-D-K-N-E-V-I-G-S-K-L-I-G-Q-N-F-T-D-P-R-Y-F-Q-G-R-V-S-S-I-E-Y-K-A-E-A-S-G-S-N-N-Y-A-P-S-N-P-D-L-E-K-R-V-E-K-S-I-E-E-W-K-K-Q-N-P-S-V-P-V-T-E-V-P-I-D-L-V-T-N-S-G-S-G-L-D-P-D-I-S-P-K-A-A-S-V-Q-V-D-R-I-S-K-L-T-D-I-P-K-E-K-L-N-Q-L-I-K-D-Q-T-E-G-A-A-L-G-L-F-G-E-T-R-V-N-V-L-K-L-N-L-A-L-Q-E-L-M-K"} +{"text": "### FUNCTION Regulates the transcription of the arc operon, involved in arginine catabolism ### SEQUENCE -M-K-K-E-K-R-Q-R-L-I-K-Q-F-V-K-E-Y-E-I-D-K-Q-E-R-L-V-E-L-L-A-K-K-D-V-L-V-T-Q-A-T-V-S-R-D-I-R-E-L-N-L-T-K-V-P-S-Q-E-G-L-M-I-Y-K-V-F-S-E-E-H-L-Q-T-D-I-K-L-K-K-K-L-R-E-V-V-V-K-I-D-C-V-D-Q-L-M-V-I-K-T-L-P-G-N-A-H-V-I-G-V-L-F-D-E-L-D-W-K-E-K-I-G-C-I-C-G-N-D-T-C-L-I-I-S-Q-S-K-S-D-R-E-I-I-E-E-R-L-N-L-I-I"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-I-G-I-G-I-D-I-I-E-L-N-R-I-E-K-M-L-D-G-K-L-K-F-M-E-R-I-L-T-E-N-E-R-N-V-A-M-E-L-K-G-S-R-L-T-E-F-V-A-G-R-F-A-A-K-E-A-Y-S-K-A-V-G-T-G-I-G-K-E-V-S-F-L-D-I-E-V-K-N-D-E-R-G-K-P-I-L-I-T-S-T-E-Y-I-V-H-L-S-I-S-H-S-K-E-F-A-V-A-Q-V-V-L-E-S-L-S-R"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-F-M-A-K-A-N-E-V-E-R-K-W-Y-V-V-D-A-E-G-Q-T-L-G-R-L-A-S-E-V-A-S-I-L-R-G-K-N-K-P-T-F-T-P-H-V-D-T-G-D-H-V-I-I-I-N-A-E-K-I-H-L-T-G-N-K-L-N-D-K-I-Y-Y-R-H-T-N-H-P-G-G-L-K-Q-R-T-A-L-E-M-R-T-N-Y-P-V-Q-M-L-E-L-A-I-K-G-M-L-P-K-G-R-L-G-R-Q-V-S-K-K-L-N-V-Y-A-G-A-E-H-P-H-Q-A-Q-K-P-E-V-Y-E-L-R-G"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-R-K-T-N-T-R-K-K-R-V-K-K-N-I-E-A-G-I-A-H-I-R-S-T-F-N-N-T-I-V-T-L-T-D-T-H-G-N-A-L-S-W-S-S-A-G-A-L-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-T-A-A-K-A-A-M-E-H-G-L-K-T-L-E-V-T-V-K-G-P-G-A-G-R-E-A-A-I-R-A-L-Q-A-A-G-L-E-V-T-A-I-R-D-V-T-P-V-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-E-G-S-R-K-V-R-N-R-V-G-R-G-I-G-S-G-N-G-K-T-A-G-K-G-H-K-G-Q-N-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-L-P-K-R-G-F-T-N-I-N-R-K-E-F-A-I-V-N-L-S-T-L-N-R-F-E-D-G-T-E-V-T-P-E-L-L-L-E-T-G-V-I-S-K-L-N-D-G-V-K-V-L-A-S-G-A-V-E-K-K-L-T-V-K-A-H-K-F-S-S-S-A-K-E-A-I-E-A-A-G-G-S-V-E-V-I"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-M-H-R-I-D-P-S-K-L-E-L-E-E-R-V-V-T-I-N-R-V-A-K-V-V-K-G-G-R-R-F-R-F-A-A-L-V-V-V-G-D-K-N-G-H-V-G-F-G-T-G-K-A-Q-E-V-P-D-A-I-R-K-A-I-E-D-A-K-K-N-L-I-A-V-P-L-V-G-T-T-I-P-H-T-I-N-G-H-F-G-A-G-E-V-F-L-K-P-A-A-E-G-T-G-V-I-A-G-G-P-V-R-A-V-L-E-L-A-G-V-Q-D-I-L-S-K-S-L-G-S-N-T-P-I-N-M-I-R-A-T-V-N-G-L-S-E-L-K-R-A-E-D-V-A-K-L-R-G-K-S-V-E-E-L-L-G"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-T-K-A-D-K-N-A-T-R-K-K-R-H-A-R-V-R-A-K-L-T-G-T-A-E-R-P-R-L-N-V-F-R-S-N-Q-H-I-Y-A-Q-V-I-D-D-V-N-G-V-T-L-V-S-A-S-T-L-D-K-D-L-A-L-N-G-T-S-N-I-E-A-A-T-K-V-G-E-S-V-A-K-R-A-V-E-K-G-V-K-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-I-L-E-I-P-A-G-V-T-I-T-V-A-E-D-N-T-V-T-V-K-G-P-K-G-E-L-T-R-T-F-N-A-D-M-L-I-K-I-E-E-N-T-L-T-V-E-R-P-S-E-Q-K-E-H-R-A-L-H-G-T-T-R-A-L-I-G-N-M-V-E-G-V-T-E-G-F-A-R-G-L-E-L-V-G-V-G-Y-R-A-Q-K-Q-G-D-K-L-V-L-S-V-G-Y-S-H-P-V-E-M-T-P-E-A-G-L-E-V-E-V-P-A-P-T-K-I-V-I-K-G-I-D-K-Q-R-V-G-E-F-A-A-N-I-R-A-V-R-A-P-E-P-Y-K-G-K-G-I-R-Y-E-G-E-V-V-R-R-K-E-G-K-T-A-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-M-L-T-R-I-R-N-A-N-M-V-R-H-E-K-L-E-V-P-A-S-K-I-K-K-E-I-A-E-L-L-K-R-E-G-F-I-R-D-V-E-Y-I-E-D-N-K-Q-G-I-L-R-I-F-L-K-Y-G-A-N-N-E-R-V-I-T-G-L-K-R-I-S-K-P-G-L-R-V-Y-A-K-A-D-E-V-P-R-V-L-N-G-L-G-I-A-L-V-S-T-S-K-G-V-M-T-D-K-D-A-R-Q-L-Q-T-G-G-E-V-V-A-Y-V-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-Q-K-R-T-P-K-F-K-V-Q-E-Y-T-R-C-E-R-C-G-R-P-H-S-V-Y-R-K-F-K-L-C-R-I-C-F-R-E-L-A-Y-K-G-Q-I-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-E-K-F-Q-K-E-I-T-P-A-L-V-S-K-F-N-Y-K-S-V-M-Q-V-P-K-I-E-K-I-V-I-N-T-G-V-G-D-A-V-S-N-S-K-A-L-D-N-A-V-E-E-L-T-Q-I-T-G-Q-K-P-V-V-T-R-A-K-K-S-I-A-G-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-Q-M-Y-E-F-F-D-K-L-V-S-V-S-L-P-R-V-R-D-F-R-G-V-S-K-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-D-Y-D-K-V-S-K-V-R-G-M-D-I-V-I-V-T-T-A-K-T-D-E-E-A-R-E-L-L-T-Q-F-G-M-P-F-Q-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-H-V-K-K-G-D-K-V-Q-V-I-T-G-K-D-K-G-K-Q-G-V-I-L-V-A-F-P-K-Q-N-R-V-I-V-E-G-V-N-I-V-K-K-H-S-K-P-S-Q-L-N-P-Q-G-G-I-I-T-K-E-A-P-I-H-V-S-N-V-M-I-L-D-P-K-T-G-E-P-T-R-V-G-F-K-V-E-D-G-K-K-V-R-I-A-K-K-S-G-E-L-L-D-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-S-G-A-R-E-L-L-T-I-K-V-L-G-G-S-G-R-K-Y-A-N-I-G-D-I-I-V-A-T-V-K-Q-A-T-P-G-G-V-V-K-K-G-D-V-V-K-A-V-V-V-R-T-K-S-G-A-R-R-P-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-K-D-D-K-S-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-S-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-R-N-Q-R-K-V-Y-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-L-V-E-T-Y-K-T-H-S-L-Y-G-K-R-V-K-Y-S-K-K-Y-K-A-H-D-E-Q-N-Q-A-K-L-G-D-I-V-K-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-D-E-I-V-E-E-A-V-I-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-Y-R-R-E-H-R-G-K-M-R-G-R-A-K-G-G-T-E-I-A-F-G-E-F-G-L-Q-A-Q-A-A-S-W-I-T-N-R-Q-I-E-A-A-R-R-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-S-K-P-Y-T-A-K-P-L-E-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-V-V-K-P-G-K-I-M-F-E-I-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-A-H-K-L-P-V-K-C-K-F-V-K-R-E-E-N-G-G-E-S-N-E-N"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-Q-A-K-A-V-A-R-T-V-R-I-A-P-R-K-V-R-L-V-V-D-L-I-R-G-K-Q-V-G-E-A-I-A-I-L-N-H-T-P-K-T-A-S-P-V-V-E-K-V-L-K-S-A-I-A-N-A-E-H-N-Y-E-M-D-I-N-N-L-V-V-E-K-V-F-V-D-E-G-P-T-L-K-R-F-R-P-R-A-M-G-R-A-S-Q-I-N-K-R-T-S-H-I-T-V-V-V-S-E-K-K-E-G"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-V-D-D-H-L-M-S-K-M-E-K-L-V-A-S-E-Q-K-Q-V-V-K-T-W-S-R-R-S-T-I-F-P-Q-F-I-G-H-T-I-A-V-Y-D-G-R-K-H-V-P-V-Y-I-T-E-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-K-G-H-L-A-D-D-K-K-T-R-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-R-D-P-R-D-I-I-K-R-P-V-I-T-E-R-S-M-E-M-M-A-E-K-K-Y-T-F-D-V-D-V-K-S-N-K-T-E-V-K-D-A-L-E-A-I-F-G-V-K-V-E-K-V-N-I-M-N-Y-K-P-K-A-K-R-V-G-R-H-A-G-F-T-S-R-R-R-K-A-I-V-K-L-T-A-D-S-K-E-I-E-I-F-Q-G-V"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-K-E-K-I-R-I-R-L-K-A-Y-D-H-R-I-L-D-Q-S-A-E-K-I-V-E-T-A-K-R-S-G-A-T-V-S-G-P-I-P-L-P-T-E-K-T-V-Y-T-I-L-R-A-V-H-K-Y-K-D-S-R-E-Q-F-E-M-R-T-H-K-R-L-I-D-I-V-S-P-T-P-Q-T-V-D-S-L-M-R-L-D-L-P-S-G-V-D-I-E-I-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-A-K-R-D-V-L-P-D-P-M-Y-N-S-K-L-V-T-R-L-I-N-K-M-M-V-D-G-K-K-G-K-S-Q-T-I-L-Y-N-A-F-D-I-V-N-E-R-T-G-K-E-P-M-E-V-F-E-Q-A-L-K-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-N-Y-A-R-L-R-G-E-K-T-M-E-E-R-L-A-N-E-I-L-D-A-A-N-N-A-G-A-S-V-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-N-G-R-T-D-K-V-W-K-S-K-S-P-A-L-N-K-G-F-N-S-L-K-K-K-S-T-D-I-S-A-P-Q-K-R-G-V-C-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-Y-A-R-V-R-L-T-N-G-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-T-A-G-V-D-K-R-M-Q-G-R-S-K-Y-G-T-K-R-P-K-P-A-K-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-T-K-E-Q-I-I-E-A-V-K-S-M-T-V-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-V-A-G-G-A-G-E-A-A-A-E-K-T-E-F-D-V-E-L-T-S-A-G-A-Q-K-I-K-V-I-K-V-V-R-E-I-T-G-L-G-L-K-E-A-K-E-L-V-D-N-T-P-K-V-I-K-E-A-A-A-K-E-E-A-E-E-I-K-A-K-L-E-E-V-G-A-A-V-E-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-K-V-M-E-T-K-Q-Q-V-V-T-E-I-A-D-K-L-R-A-S-K-S-T-I-V-V-D-Y-R-G-L-T-V-S-E-A-T-E-L-R-K-Q-L-R-E-A-G-V-E-F-K-V-Y-K-N-S-L-T-R-R-A-A-E-S-A-E-M-A-E-L-N-E-F-L-T-G-P-N-A-I-A-F-S-N-E-D-V-V-A-P-A-K-V-L-N-D-F-A-K-D-H-E-A-L-E-I-K-A-G-V-I-E-G-K-L-V-T-L-D-E-V-K-A-I-A-T-L-P-S-R-E-G-L-L-S-M-L-L-S-V-L-Q-A-P-I-R-N-L-A-L-A-T-K-A-V-A-D-Q-K-E-E-Q-G-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-I-K-M-V-K-L-Q-I-P-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-A-G-V-N-I-M-G-F-C-K-E-F-N-A-R-T-A-D-Q-A-G-L-I-I-P-V-E-I-T-V-F-E-D-R-S-F-T-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-I-E-S-G-S-G-E-P-N-R-N-K-V-A-T-V-K-R-D-K-V-R-E-I-A-E-T-K-M-P-D-L-N-A-A-S-V-E-A-A-M-R-M-V-E-G-A-A-R-S-M-G-I-V-I-E-D"} +{"text": "### FUNCTION Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 ### SEQUENCE -M-I-D-A-K-Q-L-N-S-L-A-L-A-Y-M-G-D-A-V-Y-E-Q-Y-I-R-Y-H-L-L-Q-K-G-K-V-R-P-N-Q-L-H-R-L-G-T-S-F-V-S-A-K-A-Q-A-K-V-V-Y-H-L-L-E-T-A-F-L-T-E-E-E-E-A-V-L-R-R-G-R-N-A-N-S-G-T-V-P-K-N-T-D-V-Q-T-Y-R-H-S-T-A-F-E-A-L-I-G-Y-H-H-L-L-N-N-R-E-R-L-D-E-I-V-Y-K-A-I-A-V-L-E-E-Q-E-G-G-T-S-S"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-V-G-L-G-N-P-G-R-E-Y-E-L-T-R-H-N-I-G-F-M-A-I-D-E-L-A-K-R-W-N-I-S-L-N-E-Q-K-F-K-G-V-F-G-A-G-F-V-N-G-E-K-V-I-L-L-K-P-L-T-Y-M-N-L-S-G-E-S-I-R-P-L-M-D-Y-Y-K-I-D-V-E-D-F-V-V-M-Y-D-D-L-D-I-P-V-G-K-L-R-L-R-M-K-G-S-A-G-G-H-N-G-V-K-S-T-I-S-H-L-G-T-Q-E-F-Q-R-I-R-M-G-I-D-R-P-K-N-G-M-K-V-V-D-Y-V-L-G-R-F-T-S-E-E-I-P-D-V-N-H-S-I-E-K-A-A-D-A-C-E-E-W-L-N-K-P-F-L-Q-I-M-N-T-F-N-S"} +{"text": "### FUNCTION Essential for sporulation Interferes with or is a negative regulator of the pathway leading to asymmetric septation ### SEQUENCE -M-E-V-T-D-V-R-L-R-R-V-N-T-E-G-R-M-R-A-I-A-S-I-T-L-D-H-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-G-T-R-S-K-I-Q-D-A-V-L-T-E-Y-H-R-L-G-E-L-E-E-V-E-F-E-E-A-G-A-S"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-E-K-K-D-I-F-E-S-V-S-S-M-E-E-Q-I-G-H-L-Y-K-Q-L-G-E-L-K-Q-H-L-A-E-L-L-E-E-N-Q-H-I-K-M-E-N-N-N-L-R-H-R-F-E-E-V-Q-N-K-E-K-Q-K-T-Q-K-R-K-E-V-K-P-K-T-D-I-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-N-L-H-Y-G-S-V-R-K-E-G-D-C-L-F-C-L-S-F-L-N-K-K"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-S-K-L-I-D-S-F-M-K-L-P-G-I-G-P-K-T-A-V-R-L-A-F-F-V-L-D-M-K-E-D-D-V-L-G-F-A-K-A-L-V-N-A-K-R-D-L-A-Y-C-S-V-C-G-H-I-T-D-R-D-P-C-Y-I-C-N-D-S-H-R-D-Q-S-V-V-C-V-V-Q-E-P-K-D-V-I-A-M-E-K-M-K-E-Y-Q-G-V-Y-H-V-L-R-G-A-I-S-P-M-E-G-I-G-P-E-D-I-N-I-P-Q-L-L-K-R-L-H-D-E-T-V-Q-E-V-I-L-A-T-N-P-N-I-E-G-E-A-T-A-M-Y-I-S-R-L-L-K-P-T-G-I-K-V-T-R-I-A-H-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-L-E-G-R-R-E-V"} +{"text": "### FUNCTION Negative regulator of protease production and sporulation ### SEQUENCE -M-K-S-G-E-K-D-Y-S-V-K-E-A-M-I-F-S-Q-R-I-A-Q-L-S-K-A-L-W-K-C-V-E-K-D-W-Q-M-W-I-K-P-Y-D-L-N-I-N-E-H-H-I-L-T-I-A-Y-H-L-K-G-A-S-I-S-E-I-A-K-F-G-V-M-H-V-S-T-A-F-N-F-S-K-K-L-E-E-R-G-Y-L-V-F-S-K-K-E-D-D-K-R-N-T-Y-I-E-I-T-D-K-G-E-E-L-L-L-R-L-M-E-E-Y-D-P-E-N-N-S-V-F-N-G-A-L-A-L-R-N-F-Y-G-K-F-P-E-N-I-E-L-I-A-I-L-R-N-I-Y-G-Q-D-F-I-D-I-F-E-K-S-L-E-D-I-E-E-N-F-T-E-S-D-Q-K-L-V-K-K"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-V-G-I-G-I-D-I-I-E-L-N-R-I-E-K-M-L-D-G-K-L-K-F-M-E-R-I-L-T-E-N-E-R-N-V-A-K-G-L-K-G-S-R-L-T-E-F-V-A-G-R-F-A-A-K-E-A-Y-S-K-A-V-G-T-G-I-G-K-E-V-S-F-L-D-I-E-V-R-N-D-D-R-G-K-P-I-L-I-T-S-T-E-H-I-V-H-L-S-I-S-H-S-K-E-F-A-V-A-Q-V-V-L-E-S-S-S-S"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-K-H-R-I-K-K-N-D-E-F-Q-T-V-F-Q-K-G-K-S-N-A-N-R-Q-F-V-V-Y-Q-L-D-K-E-E-Q-P-N-F-R-I-G-L-S-V-S-K-K-I-G-N-A-V-V-R-N-R-I-K-R-M-I-R-Q-S-I-T-E-L-K-D-E-I-D-S-G-K-D-F-V-I-I-A-R-K-P-C-A-E-M-T-Y-E-E-L-K-K-S-L-I-H-V-F-K-R-S-G-M-K-R-I-K-S-S-V-R-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-K-Y-E-I-M-Y-I-I-R-P-G-V-E-E-E-A-Q-K-A-L-V-E-R-F-A-G-V-L-T-N-N-G-A-E-I-I-N-T-K-E-W-G-K-R-R-L-A-Y-E-I-N-D-L-R-E-G-F-Y-M-I-L-N-V-N-A-N-A-E-A-I-N-E-F-D-R-L-A-K-I-N-E-D-I-L-R-H-I-V-V-K-E-E-E-K"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-N-R-V-I-L-V-G-R-L-T-K-D-P-D-L-R-Y-T-P-N-G-V-A-V-A-T-F-T-L-A-V-N-R-A-F-A-N-Q-Q-G-E-R-E-A-D-F-I-N-C-V-I-W-R-K-Q-A-E-N-V-A-N-Y-L-K-K-G-S-L-A-G-V-D-G-R-L-Q-T-R-N-Y-E-G-Q-D-G-K-R-V-Y-V-T-E-V-L-A-E-S-V-Q-F-L-E-P-R-N-G-G-G-E-Q-R-G-S-F-N-Q-Q-P-S-G-A-G-F-G-N-Q-S-S-N-P-F-G-Q-S-S-N-S-G-N-Q-G-N-Q-G-N-S-G-F-T-K-N-D-D-P-F-S-N-V-G-Q-P-I-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-G-R-K-G-G-R-A-K-R-R-K-V-C-F-F-T-S-N-G-I-T-R-I-D-Y-K-D-V-D-L-L-K-R-F-V-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-Y-Q-R-K-L-T-V-A-I-K-R-A-R-Q-M-A-L-L-P-Y-V-G-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-K-D-V-K-G-K-G-K-K-G-E-V-K-N-V-P-D-G-Y-A-N-N-F-L-L-K-Q-G-L-A-A-E-A-T-N-S-S-M-K-T-L-E-A-Q-K-R-K-E-E-K-D-A-A-A-E-L-E-S-A-K-Q-L-K-E-T-L-E-K-L-T-V-E-L-K-A-K-S-G-E-G-G-R-L-F-G-S-I-T-S-K-Q-I-V-D-A-M-Q-K-S-H-K-I-K-L-D-K-R-K-F-E-M-D-D-A-I-R-A-L-G-Y-T-N-V-T-V-K-L-H-P-Q-V-T-A-T-V-K-V-H-V-S-E-Q"} +{"text": "### FUNCTION Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA The LrgAB and CidA proteins may affect the proton motive force of the membrane May be involved in programmed cell death , possibly triggering PCD in response to antibiotics and environmental stresses ### SEQUENCE -M-S-T-K-K-V-Y-S-F-L-S-Q-A-F-I-F-S-A-I-M-L-I-S-N-I-I-A-T-H-L-P-I-P-M-P-S-S-V-I-G-L-V-I-L-F-S-L-L-C-L-K-V-I-K-L-E-Q-V-E-S-L-G-T-A-L-T-G-I-I-G-F-L-F-V-P-S-G-I-S-V-I-N-S-L-G-V-M-G-Q-Y-F-V-Q-I-L-T-V-I-V-V-A-T-V-I-L-L-A-V-T-G-L-F-A-Q-F-I-L-G-K-D-E-K-E-T-E-D-T-K-E-L-K-V-V-N-K-G-R-K-H-G-K-V-A"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-D-F-K-Q-Y-S-P-E-E-L-K-E-C-S-M-I-E-V-V-H-S-V-L-G-D-K-R-Q-A-T-T-F-N-E-L-V-Q-E-I-A-Q-V-L-G-L-S-Q-E-Q-V-N-A-K-I-A-Q-F-Y-T-D-L-N-I-D-G-R-F-I-N-L-G-E-N-R-W-G-L-R-S-W-Y-P-Y-E-Q-I-D-E-E-I-L-P-Q-P-K-P-K-K-K-R-K-V-E-D-D-G-F-D-D-Y-I-E-E-D-E-D-F-D-D-A-D-V-T-E-D-E-D-D-D-V-E-D-L-D-K-V-L-E-D-E-D-G-D-D-D-D-L-D-D-L-D-E-D-E-D-D-F-A-E-E-E-L-E-Y-D-E-T-E-E-E-E-E-E-L"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-T-F-E-Q-L-I-P-L-I-I-M-A-F-A-L-G-M-D-A-F-S-V-S-L-G-M-G-M-M-A-L-K-I-R-Q-I-L-Y-I-G-V-T-I-G-I-F-H-I-I-M-P-F-I-G-M-V-L-G-R-F-L-S-E-Q-Y-G-D-I-A-H-F-A-G-A-I-L-L-I-G-L-G-F-Y-I-V-Y-S-S-I-L-E-N-E-E-T-R-T-A-P-I-G-I-S-L-F-V-F-A-F-G-V-S-I-D-S-F-S-V-G-L-S-L-G-I-Y-G-A-Q-T-I-I-T-I-L-L-F-G-F-V-S-M-L-L-A-W-I-G-L-L-I-G-R-H-A-K-G-M-L-G-T-Y-G-E-I-V-G-G-I-I-L-V-G-F-G-L-Y-L-L-F-P-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-P-T-L-L-L-G-A-A-I-P-F-G-T-I-A-Y-T-L-F-I-F-L-L-L-L-V-M-L-R-K-F-A-W-G-P-L-M-G-I-M-K-E-R-E-E-H-V-A-N-E-I-D-A-A-E-R-N-N-A-E-A-K-K-L-V-E-E-Q-R-E-M-L-K-Q-S-R-V-E-A-Q-E-L-I-E-R-A-K-K-Q-A-V-D-Q-K-D-V-I-V-A-A-A-K-E-E-A-E-S-I-K-A-S-A-V-Q-E-I-Q-R-E-K-E-Q-A-I-A-A-L-Q-E-Q-V-A-S-L-S-V-Q-I-A-S-K-V-I-E-K-E-L-K-E-E-D-Q-V-K-L-I-R-D-Y-I-K-E-V-G-E-A-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-N-G-I-V-A-K-R-Y-A-V-A-L-F-K-I-A-K-E-K-H-V-L-E-M-F-E-E-E-L-R-L-V-Q-N-V-Y-E-K-N-G-E-L-H-S-F-L-T-Q-P-N-I-S-K-E-Q-K-K-T-F-L-A-N-V-F-G-S-V-S-E-S-I-L-N-T-L-Y-I-L-I-D-N-K-R-I-D-I-L-S-D-I-A-N-E-Y-V-V-L-A-N-E-E-R-N-V-A-D-A-T-V-Y-S-T-R-L-L-S-E-E-E-K-L-N-I-A-E-A-F-A-K-R-T-G-K-D-A-I-R-V-K-N-V-V-D-E-D-L-L-G-G-I-K-V-R-I-G-N-R-I-Y-D-G-S-L-Q-G-K-L-A-R-I-Q-R-E-L-M-K-N-R"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-K-T-F-P-V-S-I-V-T-P-D-G-P-V-Y-E-K-E-V-E-M-V-S-V-K-A-E-S-G-E-M-G-I-L-P-G-H-I-P-T-V-A-P-L-K-I-S-A-V-R-L-K-N-G-G-H-T-D-Y-V-A-V-S-G-G-F-I-E-V-R-P-D-K-V-T-V-L-S-S-S-A-E-E-A-N-H-I-D-I-H-R-A-N-E-A-K-R-R-A-E-Q-R-M-Q-D-K-Q-A-H-V-D-F-K-R-A-E-M-A-L-Q-R-A-V-N-R-L-N-V-S-D-M-K"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-S-V-E-S-F-E-L-D-H-T-I-V-K-A-P-Y-V-R-H-C-G-V-H-N-V-G-S-D-G-I-V-N-K-F-D-I-R-F-C-Q-P-N-K-Q-A-M-K-P-D-V-I-H-T-L-E-H-L-L-A-F-N-L-R-K-Y-I-D-R-Y-P-H-F-D-I-I-D-I-S-P-M-G-C-Q-T-G-Y-Y-L-V-V-S-G-T-P-T-V-R-E-I-I-D-L-L-E-L-T-L-K-D-A-V-Q-I-T-E-I-P-A-A-N-E-T-Q-C-G-Q-A-K-L-H-D-L-E-G-A-K-R-L-M-N-F-W-L-S-Q-D-K-D-E-L-E-K-V-F-G"} +{"text": "### FUNCTION May be involved in the biosynthesis of molybdopterin ### SEQUENCE -M-S-V-T-E-H-K-K-Q-A-P-K-E-V-R-C-K-I-V-T-I-S-D-T-R-T-E-E-T-D-K-S-G-Q-L-L-H-E-L-L-K-E-A-G-H-T-V-T-S-Y-E-I-V-K-D-D-K-E-S-I-Q-Q-A-V-L-A-G-Y-H-R-E-D-V-D-V-V-L-T-N-G-G-T-G-I-T-K-R-D-V-T-I-E-A-V-S-A-L-L-H-K-E-I-V-G-F-G-E-L-F-R-M-I-S-Y-L-E-D-I-G-S-S-A-M-L-S-R-A-I-G-G-T-I-G-R-K-V-V-F-S-M-P-G-S-S-G-A-V-R-L-A-M-N-K-L-I-L-P-E-L-G-H-I-T-F-E-L-H-R-Q"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-W-N-E-F-K-K-F-A-F-K-G-N-V-I-D-L-A-V-G-V-V-I-G-A-A-F-G-K-I-V-S-S-L-V-K-D-I-I-T-P-L-L-G-M-V-L-G-G-V-D-F-T-D-L-K-I-T-F-G-K-S-S-I-M-Y-G-N-F-I-Q-T-I-F-D-F-L-I-I-A-A-A-I-F-M-F-V-K-V-F-N-K-L-T-S-K-R-E-E-E-K-E-E-E-I-P-E-P-T-K-E-E-E-L-L-G-E-I-R-D-L-L-K-Q-Q-N-S-S-K-D-R-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-R-Y-T-G-P-A-W-K-L-S-R-R-L-G-I-S-L-S-G-T-G-K-E-L-E-K-R-P-Y-A-P-G-P-H-G-P-N-Q-R-K-K-L-S-E-Y-G-L-Q-L-Q-E-K-Q-K-L-R-H-M-Y-G-M-T-E-R-Q-F-R-R-T-F-D-Q-A-G-K-M-P-G-K-H-G-E-N-F-M-I-L-L-E-A-R-L-D-N-L-V-Y-R-M-G-L-A-R-T-R-R-A-A-R-Q-L-V-N-H-G-H-I-M-V-D-G-A-R-V-D-I-P-S-Y-R-V-K-P-G-Q-T-I-S-V-R-E-K-S-N-N-L-V-V-V-K-E-A-I-E-V-N-N-F-V-P-E-Y-L-T-F-D-A-D-K-L-E-A-T-Y-T-R-H-A-E-R-A-E-L-P-A-E-I-N-E-A-L-I-V-E-F-Y-S-R"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-S-C-S-H-N-G-T-R-V-L-D-S-R-P-V-D-E-G-R-S-I-R-R-R-R-E-C-E-S-C-L-S-R-F-T-T-F-E-R-V-E-E-S-P-L-I-V-V-K-K-E-G-T-R-E-E-F-N-K-E-K-I-L-R-G-L-I-K-A-C-E-K-R-P-V-S-L-R-Q-L-E-E-V-T-Q-S-V-E-R-E-L-R-N-L-G-I-S-E-V-K-S-D-M-I-G-E-I-V-M-E-E-L-R-D-I-D-D-V-A-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-L-N-V-F-I-E-E-L-K-D-I-L-Q-K-E-R-E"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-M-I-N-E-Q-I-R-A-R-E-V-R-L-V-G-A-N-G-D-Q-L-G-I-K-S-R-N-D-A-L-D-L-A-A-N-L-N-L-D-L-V-L-V-A-P-N-A-K-P-P-V-C-R-I-M-D-Y-G-K-F-R-F-E-Q-Q-K-K-E-K-E-Q-R-K-N-Q-K-V-I-S-M-K-E-V-R-L-S-P-T-I-D-E-H-D-F-N-T-K-L-R-N-A-I-K-F-L-E-K-G-D-K-V-K-A-S-I-R-F-K-G-R-A-I-T-H-K-E-I-G-Q-R-V-L-D-R-F-S-E-A-C-A-E-V-S-T-I-E-S-K-P-K-M-E-G-R-S-M-F-L-V-L-A-P-K-N-D-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-G-G-T-V-T-R-Q-R-R-K-K-V-I-K-L-A-K-G-Y-Y-G-S-K-N-T-L-F-K-V-A-N-Q-Q-V-M-K-S-L-M-Y-A-F-R-D-R-R-Q-K-K-R-D-F-R-K-L-W-I-T-R-I-N-A-A-A-R-M-N-G-L-S-Y-S-R-L-M-H-G-L-K-N-A-G-I-E-V-N-R-K-M-L-A-D-L-A-V-H-D-E-K-A-F-A-E-L-A-T-V-A-K-N-N-I-N"} +{"text": "### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-S-Q-Q-K-G-K-K-S-R-I-N-V-E-I-Y-G-Q-Q-Y-S-V-V-G-D-E-S-T-S-H-I-R-M-V-A-A-I-V-D-D-K-M-R-E-L-N-A-K-N-P-S-L-D-T-S-R-L-A-V-L-T-A-V-N-V-I-H-D-Y-I-K-L-K-E-E-H-E-K-L-K-E-S-M-T-K-K-G-M-E"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-K-V-T-K-A-D-I-V-I-S-A-V-K-P-E-Q-Y-P-D-G-D-L-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-K-I-L-N-R-K-K-L-V-R-I-S-S-K-P-G-K-T-Q-T-L-N-F-F-L-I-N-E-M-M-H-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-T-E-R-A-A-W-G-K-M-I-E-T-Y-F-T-T-R-E-Q-L-D-A-A-V-L-V-V-D-L-R-H-K-P-T-N-D-D-V-M-M-Y-D-F-L-K-H-Y-D-I-P-T-I-I-I-A-T-K-A-D-K-I-P-K-G-K-W-Q-K-H-L-K-V-V-K-E-T-L-D-I-E-S-G-D-E-V-V-L-F-S-S-E-T-G-L-G-K-E-E-A-W-K-A-I-H-K-F-T-K-T-K-N-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-E-T-G-G-K-Q-I-K-V-E-A-G-Q-A-I-Y-I-E-K-L-D-V-E-A-G-E-T-V-T-F-D-K-V-L-F-V-G-G-E-N-V-K-V-G-S-P-V-V-E-G-A-T-V-T-A-K-V-E-K-Q-G-R-A-K-K-I-I-V-F-K-Y-K-A-K-K-N-N-R-K-K-Q-G-H-R-Q-P-Y-T-K-L-V-V-E-A-I-N-A"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-F-K-Q-H-I-A-I-V-P-D-Y-P-K-E-G-I-V-F-K-D-I-T-P-L-M-N-D-G-K-A-Y-K-A-A-T-D-A-I-V-E-Y-A-K-E-R-D-I-D-L-V-V-G-P-E-A-R-G-F-I-I-G-C-P-V-S-Y-A-L-E-V-G-F-A-P-V-R-K-L-G-K-L-P-R-E-V-I-T-V-D-Y-G-K-E-Y-G-K-D-V-L-T-I-H-K-D-A-I-K-P-G-Q-R-V-L-I-T-D-D-L-L-A-T-G-G-T-I-E-A-T-I-K-L-V-E-E-L-G-G-V-V-A-G-I-A-F-L-V-E-L-T-Y-L-D-G-R-K-M-L-D-G-Y-D-V-L-V-L-E-K-Y"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-L-G-L-D-V-G-T-K-T-V-G-V-A-I-S-D-E-M-G-W-T-A-Q-G-L-E-T-I-K-I-N-E-E-R-G-Q-F-G-F-D-R-I-S-E-L-V-K-Q-Y-D-V-D-K-I-V-V-G-L-P-K-N-M-N-G-T-I-G-P-R-G-E-A-C-Q-Q-F-A-E-N-L-R-E-L-L-Q-L-D-V-V-M-W-D-E-R-L-S-T-M-A-A-E-R-L-L-I-S-A-D-V-S-R-K-K-R-K-Q-V-I-D-K-M-A-A-V-V-I-L-Q-G-F-L-D-S-K"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-T-E-K-T-Y-P-M-T-Q-E-G-K-Q-K-L-E-N-E-L-E-D-L-K-T-V-K-R-K-E-V-V-E-R-I-K-I-A-R-S-F-G-D-L-S-E-N-S-E-Y-D-A-A-K-D-E-Q-A-F-V-E-G-R-I-T-Q-L-E-N-M-I-R-N-A-V-I-I-T-D-N-G-E-E-S-T-V-V-T-L-G-K-T-V-T-F-K-E-L-P-N-G-D-E-E-A-Y-T-I-V-G-S-A-E-A-D-P-F-E-G-R-I-S-N-D-S-P-I-A-K-S-L-L-G-K-Q-I-G-E-K-V-A-I-Q-T-P-G-G-E-M-Q-V-E-I-I-S-V-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-A-K-L-S-E-E-R-R-A-H-N-A-S-I-K-S-D-M-R-S-A-V-K-T-V-E-A-L-V-T-N-N-D-L-E-N-A-K-E-A-F-K-T-A-S-K-K-L-D-K-A-A-R-K-G-L-I-H-Q-N-A-A-A-R-Q-K-S-R-L-A-K-Q-V-N-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-E-E-R-N-E-Q-V-V-E-E-V-K-E-A-Q-V-E-E-A-V-T-P-E-N-S-E-E-T-V-E-E-K-S-E-A-A-L-L-Q-E-K-V-D-E-L-Q-A-K-L-T-E-T-E-G-R-T-L-R-L-Q-A-D-F-E-N-Y-K-R-R-V-Q-M-D-K-Q-A-A-E-K-Y-R-A-Q-S-L-V-S-D-I-L-P-A-L-D-N-F-E-R-A-M-Q-V-E-A-T-D-E-Q-T-K-S-L-L-Q-G-M-E-M-V-H-R-Q-L-L-E-A-L-N-K-E-G-V-E-V-I-E-A-V-G-K-Q-F-D-P-N-E-H-Q-A-I-M-Q-V-E-D-S-E-F-E-S-N-A-V-V-E-E-F-Q-K-G-Y-K-L-K-D-R-V-I-R-P-S-M-V-K-V-N-Q"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-L-L-I-D-F-I-D-E-T-E-E-V-K-E-E-Y-V-N-L-I-R-E-I-L-G-K-A-A-Q-M-E-K-I-E-D-G-A-E-L-S-V-T-F-V-D-N-E-R-I-R-E-I-N-R-D-Y-R-D-K-D-Q-P-T-D-V-I-S-F-A-M-E-E-M-G-E-G-E-M-E-I-V-G-V-E-M-P-R-M-L-G-D-L-I-I-S-I-P-R-A-K-E-Q-A-E-E-Y-G-H-S-F-D-R-E-L-G-F-L-A-L-H-G-F-L-H-L-L-G-Y-D-H-M-T-E-E-D-E-K-E-M-F-G-R-Q-K-E-I-L-E-A-F-G-L-G-R"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-R-R-T-A-R-E-R-A-M-Q-A-L-Y-Q-M-D-I-T-G-E-L-E-P-K-V-A-V-E-N-T-L-D-E-G-E-E-T-N-E-F-L-E-S-L-V-V-G-F-V-E-N-K-E-V-I-D-E-A-I-R-Q-N-L-K-K-W-K-L-E-R-I-S-I-V-D-R-S-I-L-R-V-A-V-Y-E-M-K-Y-M-E-E-I-P-H-N-V-T-I-N-E-A-I-E-I-A-K-T-F-G-D-E-E-S-R-R-F-I-N-G-V-L-S-N-I-K-D-T-L"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-E-N-K-L-S-F-E-E-A-I-S-Q-L-E-H-L-V-S-K-L-E-Q-G-D-V-P-L-E-E-A-I-S-Y-F-K-E-G-M-E-L-S-K-L-C-D-E-K-L-K-N-V-Q-E-Q-M-A-V-I-L-G-E-D-G-E-L-E-P-F-T-A-L-G-D-E-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-G-Q-R-H-I-K-I-R-E-I-I-A-N-K-E-I-E-T-Q-D-E-L-V-D-I-L-R-N-E-G-F-N-V-T-Q-A-T-V-S-R-D-I-K-E-L-H-L-V-K-V-P-L-H-D-G-R-Y-K-Y-S-L-P-A-D-Q-R-F-N-P-L-Q-K-L-K-R-N-L-V-D-S-F-V-K-L-D-T-A-G-H-M-L-V-L-K-T-L-P-G-N-A-H-S-L-G-A-L-I-D-H-L-E-W-D-E-I-I-G-T-I-C-G-D-D-T-C-L-I-I-C-R-T-P-E-D-T-G-V-V-S-D-R-F-L-N-M-L"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-D-R-T-E-Q-K-S-I-I-E-G-L-L-F-V-S-G-D-E-G-I-Y-P-E-Q-I-A-K-V-L-E-I-E-G-N-E-V-I-D-I-L-E-E-M-Q-K-E-C-E-G-A-H-R-G-L-Q-I-V-Q-Y-A-K-V-Y-R-F-A-T-K-K-E-H-A-S-Y-Y-Q-K-L-I-E-I-P-T-A-A-S-L-S-Q-A-A-L-E-T-L-A-I-V-A-Y-R-Q-P-I-T-R-T-E-M-E-E-I-R-G-V-K-T-D-K-A-L-Q-T-L-V-S-H-L-L-I-K-E-M-G-R-A-E-G-P-G-R-P-I-L-Y-G-T-T-K-E-F-L-D-T-F-G-L-K-T-L-D-D-L-P-P-L-S-E-E-N-E-Q-M-N-E-A-D-L-F-F-G-S-L-Q-E-I-S-K"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-F-K-V-F-Y-Q-E-K-M-T-E-V-P-V-R-E-N-T-K-V-L-Y-L-E-A-T-S-E-K-D-V-R-T-K-L-N-K-F-A-Y-N-I-E-F-V-Q-S-V-T-G-N-H-L-E-Y-E-K-A-N-A-D-L-T-L-A-E-I-V"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-L-T-M-K-D-V-I-R-E-G-D-P-I-L-R-N-V-A-E-E-V-V-I-P-A-S-E-E-D-T-N-T-L-K-E-M-I-E-F-V-I-N-S-Q-D-P-E-M-A-E-K-Y-S-L-R-P-G-I-G-L-A-A-P-Q-I-G-I-S-K-K-M-I-A-V-H-V-T-D-T-D-G-T-L-Y-S-H-A-L-F-N-P-K-I-I-S-H-S-V-E-R-T-Y-L-Q-S-G-E-G-C-L-S-V-D-R-E-V-P-G-Y-V-P-R-Y-T-R-I-T-V-K-A-T-S-I-N-G-E-E-V-K-L-R-L-K-G-L-P-A-I-V-F-Q-H-E-I-D-H-L-N-G-V-M-F-Y-D-H-I-N-K-E-N-P-F-A-A-P-D-G-S-K-P-L-E-R"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-V-L-Y-T-T-A-S-C-A-S-C-R-K-A-K-A-W-L-E-E-N-Q-I-D-Y-T-E-K-N-I-V-S-N-S-M-T-V-D-E-L-K-S-I-L-R-L-T-E-E-G-A-T-E-I-I-S-T-R-S-K-T-F-Q-D-L-N-I-N-I-E-E-L-S-L-N-E-F-Y-K-L-I-I-E-H-P-L-M-L-R-R-P-I-M-L-D-E-K-R-L-Q-I-G-F-N-D-E-E-I-R-K-F-L-P-R-S-V-R-T-F-L-N-I-E-L-Q-K-L-A-N"} +{"text": "### FUNCTION Catalyzes the reduction of arsenate ### SEQUENCE -M-E-N-K-K-T-I-Y-F-L-C-T-G-N-S-C-R-S-Q-M-A-E-A-W-G-K-Q-Y-L-G-D-K-W-N-V-Y-S-A-G-I-E-A-H-G-V-N-P-N-A-I-K-A-M-N-E-V-N-I-D-I-T-N-Q-T-S-D-I-I-D-A-N-I-L-N-R-A-D-L-V-V-T-L-C-S-H-A-D-A-V-C-P-S-T-P-P-H-V-N-R-V-H-W-G-F-D-D-P-A-G-K-E-W-P-E-F-Q-R-V-R-D-E-I-G-E-R-I-K-R-F-S-E-T-G-E"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-A-I-P-Y-V-V-E-Q-T-K-L-G-E-R-S-Y-D-I-Y-S-R-L-L-K-D-R-I-V-I-I-G-S-E-I-N-D-Q-V-A-S-S-V-V-A-Q-L-L-F-L-E-A-E-D-A-E-K-D-I-F-L-Y-I-N-S-P-G-G-S-T-T-A-G-F-A-I-L-D-T-M-N-L-I-K-P-D-V-Q-T-L-C-M-G-F-A-A-S-F-G-A-L-L-L-L-S-G-A-K-G-K-R-F-A-L-P-N-S-E-I-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-T-E-I-E-I-T-A-K-R-I-L-K-L-K-H-D-I-N-K-M-I-A-E-K-T-G-Q-P-I-E-R-V-A-H-D-T-E-R-D-Y-F-M-T-A-E-E-A-K-A-Y-G-I-V-D-D-V-V-T-K-K"} +{"text": "### FUNCTION Possible metal-dependent hydrolase ### SEQUENCE -M-N-D-L-R-Y-P-I-G-Q-F-T-Y-K-R-P-I-T-E-E-M-I-D-T-W-I-Q-E-I-E-D-L-P-N-E-L-T-K-A-I-K-D-L-D-Q-K-Q-L-D-T-P-Y-R-V-G-G-W-T-V-R-Q-V-V-H-H-V-V-D-S-H-M-N-S-Y-I-R-F-K-L-A-L-T-E-K-N-P-T-I-K-P-Y-K-E-E-K-W-A-E-L-P-D-S-K-L-P-V-D-V-S-L-V-M-L-E-S-L-H-K-R-W-V-N-L-L-Y-S-L-E-L-E-D-L-E-K-T-F-N-H-P-D-T-G-E-T-K-L-A-A-A-I-G-L-Y-A-W-H-G-R-H-H-T-A-H-I-T-S-L-R-K-R-L-N-W"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-L-Y-N-I-N-K-R-L-Y-L-F-E-K-G-R-E-E-M-A-E-V-N-V-K-K-S-S-F-F-K-E-K-K-E-V-P-N-T-D-F-S-L-L-K-G-A-L-I-Q-N-L-D-R-L-E-K-F-V-E-A-I-P-Y-K-Y-I-K-E-G-N-V-K-E-N-A"} +{"text": "### FUNCTION Can bind to ATTGG and CCAAT motifs of single-stranded oligonucleotides ### SEQUENCE -M-T-L-T-G-K-V-K-W-F-N-S-E-K-G-F-G-F-I-E-V-E-G-G-N-D-V-F-V-H-F-S-A-I-T-G-D-G-F-K-S-L-D-E-G-Q-E-V-S-F-E-V-E-D-G-N-R-G-P-Q-A-K-N-V-V-K-L"} +{"text": "### FUNCTION Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure ### SEQUENCE -M-E-Y-K-T-P-F-I-A-K-K-L-G-V-S-P-K-A-V-V-R-I-A-Q-Q-L-N-L-T-I-E-K-N-K-Y-G-H-F-I-F-T-Q-D-D-L-D-Q-M-L-E-Y-H-R-S-Q-I-E-Q-S-Q-N-T-H-P-T-Q-K-T-S-S-N-D-V-E-E-L-K-T-Q-V-N-T-I-V-Q-N-I-S-S-H-D-F-E-Q-L-A-A-Q-L-N-T-I-T-R-R-L-D-R-M-E-E-Q-M-Q-D-K-A-N-D-V-V-T-Y-Q-L-L-Q-H-R-R-E-M-E-E-M-L-E-R-I-Q-K-L-E-A-G-L-K-K-E-E-P-I-Y-I-T-P-D-T-K-P-T-Y-E-R-E-K-K-P-K-R-R-K-M-I-F-S-I-F-G-L"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-F-S-N-I-G-F-P-G-L-I-L-I-L-V-A-V-L-I-L-F-G-P-K-K-L-P-E-I-G-K-A-L-G-E-T-L-K-E-F-K-K-S-T-K-E-L-T-D-D-A-F-Q-E-K-E-K-K-E-K-M"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-I-S-D-K-I-K-L-T-A-K-D-I-L-E-K-E-F-K-T-G-M-R-G-Y-Q-Q-E-E-V-D-K-F-L-D-M-I-I-K-D-Y-E-A-F-H-K-E-F-E-Q-L-K-Q-Q-N-A-R-L-K-R-E-L-E-E-Q-K-L-A-A-T-Q-V-P-Q-Q-P-V-V-Q-T-P-V-A-Q-P-V-Y-N-N-T-N-T-D-I-L-K-R-L-S-N-L-E-K-A-V-F-G-S-K-L-Y-E"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-K-I-A-L-I-A-H-D-K-K-K-E-D-M-V-S-F-A-Y-A-Y-K-P-I-F-E-Q-H-E-L-F-A-T-G-T-T-G-L-R-I-M-E-A-T-G-L-V-V-T-R-Y-Q-S-G-P-L-G-G-D-Q-E-I-G-A-M-I-A-K-N-D-L-D-M-V-I-F-F-R-D-P-L-T-A-Q-P-H-E-P-D-V-N-A-L-L-R-L-C-D-V-Y-A-I-P-L-A-T-N-M-A-S-A-E-M-L-M-H-A-L-E-R-G-D-L-D-Y-R-K-L-R-K"} +{"text": "### FUNCTION Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c ### SEQUENCE -M-K-K-N-R-L-L-F-R-V-I-I-L-L-I-L-S-G-A-V-G-F-T-L-Y-Q-G-F-F-A-D-K-E-K-M-Q-I-G-K-E-A-P-N-F-V-V-T-D-L-E-G-K-K-I-E-L-K-D-L-K-G-K-G-V-F-L-N-F-W-G-T-W-C-K-P-C-E-K-E-M-P-Y-M-N-E-L-Y-P-K-Y-K-E-K-G-V-E-I-I-A-L-D-A-D-E-T-D-I-A-V-K-N-F-V-N-Q-Y-G-L-K-F-P-V-A-I-D-K-G-Q-K-I-I-G-T-Y-G-V-G-P-L-P-T-S-F-L-I-D-K-D-G-K-V-V-E-Q-I-I-G-E-Q-T-K-E-Q-L-E-G-Y-L-K-K-I-T-P"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-P-F-R-I-H-K-G-T-A-A-V-L-M-N-D-N-I-D-T-D-Q-I-I-P-K-Q-Y-L-K-R-I-E-R-T-G-F-G-K-F-L-F-D-E-W-R-Y-D-N-E-R-H-E-N-P-N-F-P-L-N-A-P-D-R-K-G-A-S-I-L-I-T-G-N-N-F-G-C-G-S-S-R-E-H-A-P-W-A-L-A-D-Y-G-F-R-V-I-I-A-G-G-F-A-D-I-F-Y-M-N-C-M-K-N-G-M-L-P-I-V-M-D-K-E-M-R-E-K-L-V-K-T-D-A-R-E-Q-I-E-V-D-L-E-N-E-V-I-T-T-S-T-H-R-F-H-F-T-I-E-K-M-W-K-E-K-L-L-N-G-L-D-E-I-S-I-T-M-Q-Y-E-Q-E-I-K-E-Y-E-R-R-I-A-A-Y"} +{"text": "### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-A-E-F-K-E-Q-V-L-D-I-L-E-E-V-C-E-N-D-I-V-K-E-N-L-D-V-Q-L-F-E-E-G-I-L-D-S-F-A-V-V-S-L-L-V-E-F-Q-E-R-L-D-I-E-V-S-I-S-D-F-D-R-D-E-W-A-T-P-N-M-V-I-K-K-L-E-E-I-R"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-T-L-Y-S-S-P-S-C-T-S-C-R-K-A-K-L-W-L-E-E-N-H-I-P-Y-T-E-R-N-I-F-S-D-P-L-T-I-E-E-I-K-E-I-L-R-M-T-E-S-G-T-D-E-I-I-S-T-R-S-K-V-F-Q-E-L-N-V-N-L-E-S-L-P-L-Q-D-L-Y-K-M-I-R-D-Y-P-G-I-L-R-R-P-I-M-I-D-E-K-R-L-Q-V-G-Y-N-E-D-E-I-R-R-F-L-P-R-T-V-R-T-F-Q-L-R-E-A-Q-R-L-V-N"} +{"text": "### FUNCTION Can bind to ATTGG and CCAAT motifs of single-stranded oligonucleotides ### SEQUENCE -M-A-V-T-G-Q-V-K-W-F-N-N-E-K-G-F-G-F-I-E-V-P-G-E-N-D-V-F-V-H-F-S-A-I-E-T-D-G-F-K-S-L-E-E-G-Q-K-V-S-F-E-I-E-E-G-N-R-G-P-Q-A-K-N-V-I-K-L"} +{"text": "### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-G-R-E-K-K-Q-E-Y-A-L-F-T-A-W-G-A-S-F-I-A-T-L-G-S-L-Y-F-S-E-I-M-K-F-E-P-C-V-L-C-W-Y-Q-R-I-F-M-Y-P-F-V-L-W-L-G-I-A-V-V-K-K-D-Y-R-I-A-S-Y-S-L-P-I-A-S-I-G-A-C-I-S-L-Y-H-Y-V-I-Q-K-V-A-A-F-S-A-A-G-A-A-C-G-R-V-P-C-T-G-E-Y-I-N-W-F-G-F-V-T-I-P-F-L-A-L-I-G-F-I-T-I-A-V-C-S-F-I-V-I-K-N-K"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-A-K-K-Q-S-I-L-S-P-I-I-R-I-T-F-T-F-L-V-L-C-G-L-V-Y-P-L-I-V-T-G-I-A-Q-A-V-M-K-D-N-A-D-G-S-L-I-Y-N-D-K-N-E-V-I-G-S-K-L-I-G-Q-N-F-T-D-P-R-Y-F-H-G-R-V-S-S-I-E-Y-K-A-E-A-S-G-S-N-N-Y-A-P-S-N-P-D-L-E-K-R-V-E-K-S-I-E-E-W-K-K-Q-N-P-S-V-P-V-T-E-V-P-I-D-L-V-T-N-S-G-S-G-L-D-P-D-I-S-P-K-A-A-S-V-Q-V-E-R-I-S-K-L-T-N-I-P-K-E-T-L-D-Q-L-I-K-D-Q-T-E-G-A-A-L-G-L-F-G-E-T-R-V-N-V-L-K-L-N-L-G-L-Q-K-I-M-K"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-I-E-L-V-Q-A-E-E-K-T-A-S-G-I-V-L-P-D-T-A-K-E-K-P-Q-E-G-K-V-I-A-V-G-T-G-R-V-L-E-N-G-E-R-V-A-L-E-V-A-A-G-D-L-I-I-F-S-K-Y-A-G-T-E-V-K-Y-E-G-T-D-Y-L-I-L-R-E-S-D-I-L-A-V-I-G"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-F-M-A-K-A-N-E-V-E-R-K-W-Y-V-V-D-A-E-G-Q-T-L-G-R-L-A-S-E-V-A-S-I-L-R-G-K-N-K-P-T-F-T-P-H-V-D-T-G-D-H-V-I-I-I-N-A-E-K-I-H-L-T-G-N-K-L-N-D-K-I-Y-Y-R-H-T-N-H-P-G-G-L-K-Q-R-T-A-L-E-M-R-T-N-Y-P-V-Q-M-L-E-L-A-I-K-G-M-L-P-K-G-R-L-G-R-Q-V-S-K-K-L-N-V-Y-A-G-A-E-H-P-H-Q-A-Q-K-P-E-V-Y-E-L-R-G"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-R-K-T-N-T-R-K-K-R-V-K-K-N-I-E-A-G-V-A-H-I-R-S-T-F-N-N-T-I-V-T-L-T-D-T-H-G-N-A-L-S-W-S-S-A-G-A-L-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-T-A-A-K-A-A-M-E-H-G-L-K-T-L-E-V-T-V-K-G-P-G-A-G-R-E-A-A-I-R-A-L-Q-A-A-G-L-E-V-T-A-I-R-D-V-T-P-V-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-E-V-E-G-T-V-L-E-T-L-P-N-A-M-F-K-V-E-L-E-N-G-H-V-V-L-A-H-V-S-G-K-I-R-M-N-F-I-R-I-L-P-G-D-K-V-T-V-E-L-S-P-Y-D-L-N-R-G-R-I-T-Y-R-F-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-E-G-S-R-K-V-R-N-R-V-G-R-G-I-G-S-G-N-G-K-T-A-G-K-G-H-K-G-Q-N-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-L-P-K-R-G-F-T-N-I-N-R-K-E-F-A-I-V-N-L-S-T-L-N-R-F-E-D-G-T-E-V-T-P-E-L-L-L-E-T-G-V-I-S-K-L-N-D-G-V-K-I-L-A-S-G-A-V-E-K-K-L-T-V-K-A-H-K-F-S-S-S-A-K-E-A-I-E-A-A-G-G-S-V-E-V-I"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-H-R-I-D-P-S-K-L-E-L-E-E-R-V-V-T-I-N-R-V-A-K-V-V-K-G-G-R-R-F-R-F-A-A-L-V-V-V-G-D-K-N-G-H-V-G-F-G-T-G-K-A-Q-E-V-P-D-A-I-R-K-A-I-E-D-A-K-K-N-L-I-A-V-P-L-V-G-T-T-I-P-H-T-I-N-G-H-F-G-A-G-E-V-F-L-K-P-A-A-E-G-T-G-V-I-A-G-G-P-V-R-A-V-L-E-L-A-G-V-Q-D-I-L-S-K-S-L-G-S-N-T-P-I-N-M-I-R-A-T-V-N-G-L-S-E-L-K-R-A-E-D-V-A-K-L-R-G-K-S-V-E-E-L-L-G"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-T-K-A-D-K-N-A-T-R-K-K-R-H-A-R-V-R-A-K-L-T-G-T-A-E-R-P-R-L-N-V-F-R-S-N-Q-H-I-Y-A-Q-V-I-D-D-V-N-G-V-T-L-V-S-A-S-T-L-D-K-D-L-A-L-N-G-T-S-N-I-E-A-A-T-K-V-G-E-S-V-A-K-R-A-V-E-K-G-V-K-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-I-L-E-I-P-A-G-V-T-I-T-V-A-E-D-N-T-V-T-V-K-G-P-K-G-E-L-T-R-T-F-N-A-D-M-L-I-K-I-E-E-N-T-L-T-V-E-R-P-S-E-Q-K-E-H-R-A-L-H-G-T-T-R-A-L-I-G-N-M-V-E-G-V-T-E-G-F-A-R-G-L-E-L-V-G-V-G-Y-R-A-Q-K-Q-G-D-K-L-V-L-S-V-G-Y-S-H-P-V-E-M-T-P-E-A-G-L-E-V-E-V-P-A-P-T-K-I-V-I-K-G-I-D-K-Q-R-V-G-E-F-A-A-N-I-R-A-V-R-A-P-E-P-Y-K-G-K-G-I-R-Y-E-G-E-V-V-R-R-K-E-G-K-T-A-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-M-L-T-R-I-R-N-A-N-M-V-R-H-E-K-L-E-V-P-A-S-K-I-K-K-E-I-A-E-L-L-K-R-E-G-F-I-R-D-V-E-Y-I-E-D-N-K-Q-G-I-L-R-I-F-L-K-Y-G-A-N-N-E-R-V-I-T-G-L-K-R-I-S-K-P-G-L-R-V-Y-A-K-A-D-E-V-P-R-V-L-N-G-L-G-I-A-L-V-S-T-S-K-G-V-M-T-D-K-D-A-R-Q-L-Q-T-G-G-E-V-V-A-Y-V-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-Q-K-R-T-P-K-F-K-V-Q-E-Y-T-R-C-E-R-C-G-R-P-H-S-V-Y-R-K-F-K-L-C-R-I-C-F-R-E-L-A-Y-K-G-Q-I-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-E-K-F-Q-K-E-I-T-P-A-L-V-S-K-F-N-Y-K-S-V-M-Q-V-P-K-I-E-K-I-V-I-N-T-G-V-G-D-A-V-S-N-S-K-T-L-D-N-A-V-E-E-L-T-Q-I-T-G-Q-K-P-V-V-T-R-A-K-K-S-I-A-G-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-Q-M-Y-E-F-F-D-K-L-V-S-V-S-L-P-R-V-R-D-F-R-G-V-S-K-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-D-Y-D-K-V-S-K-V-R-G-M-D-I-V-I-V-T-T-A-K-T-D-E-E-A-R-E-L-L-T-Q-F-G-M-P-F-Q-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-H-V-K-K-G-D-K-V-Q-V-I-T-G-K-D-K-G-K-Q-G-V-I-L-V-A-F-P-K-Q-N-R-V-I-V-E-G-V-N-I-V-K-K-H-S-K-P-S-Q-L-N-P-Q-G-G-I-I-T-K-E-A-P-I-H-V-S-N-V-M-I-L-D-P-K-T-G-E-P-T-R-V-G-F-K-V-E-D-G-K-K-V-R-I-A-K-K-S-G-E-L-L-D-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-S-G-A-R-E-L-L-T-I-K-V-L-G-G-S-G-R-K-Y-A-N-I-G-D-I-I-V-A-T-V-K-Q-A-T-P-G-G-V-V-K-K-G-D-V-V-K-A-V-V-V-R-T-K-S-G-A-R-R-P-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-K-D-D-K-S-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-S-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-R-N-Q-R-K-V-Y-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-L-V-E-T-Y-K-T-H-S-L-Y-G-K-R-V-K-Y-S-K-K-Y-K-A-H-D-E-Q-N-Q-A-K-L-G-D-I-V-K-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-I-V-E-E-A-V-I-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-Y-R-R-E-H-R-G-K-M-R-G-R-A-K-G-G-T-E-I-A-F-G-E-F-G-L-Q-A-Q-A-A-S-W-I-T-N-R-Q-I-E-A-A-R-R-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-S-K-P-Y-T-A-K-P-L-E-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-V-V-K-P-G-K-I-M-F-E-I-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-A-H-K-L-P-V-K-C-K-F-V-K-R-E-E-N-G-G-E-S-N-E-N"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-Q-A-K-A-V-A-R-T-V-R-I-A-P-R-K-V-R-L-V-V-D-L-I-R-G-K-Q-V-G-E-A-I-A-I-L-N-H-T-P-K-T-A-S-P-V-V-E-K-V-L-K-S-A-I-A-N-A-E-H-N-Y-E-M-D-I-N-S-L-V-V-E-K-V-F-V-D-E-G-P-T-L-K-R-F-R-P-R-A-M-G-R-A-S-Q-I-N-K-R-T-S-H-I-T-V-V-V-S-E-K-K-E-G"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-V-D-D-H-L-M-S-K-I-A-K-L-N-E-T-E-Q-K-Q-V-V-K-T-W-S-R-R-S-T-I-F-P-Q-F-I-G-H-T-I-A-V-Y-D-G-R-K-H-V-P-V-Y-V-T-E-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-K-G-H-D-A-D-D-K-K-T-R-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-R-D-P-R-D-I-I-K-R-P-V-I-T-E-R-S-M-E-M-M-A-E-K-K-Y-T-F-D-V-D-V-K-S-N-K-T-E-V-K-D-A-L-E-A-I-F-G-V-K-V-E-K-V-N-I-M-N-Y-K-P-K-A-K-R-V-G-R-H-A-G-F-T-S-R-R-R-K-A-I-V-K-L-T-A-D-S-K-E-I-E-I-F-Q-G-V"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-K-E-K-I-R-I-R-L-K-A-Y-D-H-R-I-L-D-Q-S-A-D-K-I-V-E-T-A-K-R-S-G-A-T-V-S-G-P-I-P-L-P-T-E-K-T-V-Y-T-I-L-R-A-V-H-K-Y-K-D-S-R-E-Q-F-E-M-R-T-H-K-R-L-I-D-I-V-S-P-T-P-Q-T-V-D-S-L-M-R-L-D-L-P-S-G-V-D-I-E-I-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-A-K-R-D-V-L-P-D-P-M-Y-N-S-K-L-V-T-R-L-I-N-K-M-M-V-D-G-K-K-G-K-S-Q-T-I-L-Y-N-A-F-D-I-V-S-E-R-T-G-K-E-P-M-E-V-F-E-Q-A-L-K-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-N-Y-A-R-L-R-G-E-K-T-M-E-E-R-L-A-N-E-I-L-D-A-A-N-N-A-G-A-S-V-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-N-G-R-T-D-K-V-W-K-S-K-S-P-A-L-N-K-G-F-N-S-L-K-K-K-S-T-D-I-S-A-P-Q-K-R-G-V-C-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-Y-A-R-V-R-L-T-N-G-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-T-A-G-V-D-K-R-M-Q-G-R-S-K-Y-G-T-K-K-P-K-A-A-K-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-T-K-E-Q-I-I-E-A-V-K-S-M-T-V-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-V-A-G-G-A-G-E-A-A-A-E-K-T-E-F-D-V-E-L-T-S-A-G-A-Q-K-I-K-V-I-K-V-V-R-E-I-T-G-L-G-L-K-E-A-K-E-L-V-D-N-T-P-K-V-I-K-E-A-A-A-K-E-E-A-E-E-I-K-A-K-L-E-E-V-G-A-A-V-E-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-K-V-I-E-T-K-Q-Q-V-V-T-E-I-A-D-K-L-R-A-S-K-S-T-I-V-V-D-Y-R-G-L-T-V-S-E-A-T-E-L-R-K-Q-L-R-E-A-G-V-E-F-K-V-Y-K-N-S-L-T-R-R-A-A-E-S-A-E-M-A-E-L-N-E-F-L-T-G-P-N-A-I-A-F-S-N-E-D-V-V-A-P-A-K-V-L-N-D-F-A-K-D-H-E-A-L-E-I-K-A-G-V-I-E-G-K-L-V-T-L-D-E-V-K-A-I-A-T-L-P-S-R-E-G-L-L-S-M-L-L-S-V-L-Q-A-P-I-R-N-L-A-L-A-T-K-A-V-A-D-Q-K-E-E-Q-G-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-I-K-M-V-K-L-Q-I-P-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-A-G-V-N-I-M-G-F-C-K-E-F-N-A-R-T-A-D-Q-A-G-L-I-I-P-V-E-I-T-V-F-E-D-R-S-F-T-F-I-T-K-T-P-P-A-A-V-L-L-K-K-V-A-G-I-E-S-G-S-G-E-P-N-R-N-K-V-A-T-V-K-R-D-K-V-R-E-I-A-E-T-K-M-P-D-L-N-A-A-S-V-E-A-A-M-R-M-V-E-G-T-A-R-S-M-G-I-V-I-E-D"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-V-G-L-G-N-P-G-R-E-Y-E-L-T-R-H-N-I-G-F-M-A-I-D-E-L-A-K-R-W-N-I-S-L-N-E-Q-K-F-K-G-L-F-G-A-G-F-V-N-G-E-K-V-I-L-L-K-P-L-T-Y-M-N-L-S-G-E-S-I-R-P-L-M-D-Y-Y-K-I-D-V-E-D-F-V-V-L-Y-D-D-L-D-I-P-V-G-K-L-R-L-R-M-K-G-S-A-G-G-H-N-G-V-K-S-T-I-S-H-L-G-T-Q-E-F-Q-R-I-R-M-G-I-D-R-P-K-N-G-M-K-V-V-D-Y-V-L-G-R-F-T-S-E-E-I-P-D-V-N-H-S-I-E-K-A-A-D-A-C-E-E-W-L-N-K-P-F-L-Q-I-M-N-T-F-N-S"} +{"text": "### FUNCTION Essential for sporulation Interferes with or is a negative regulator of the pathway leading to asymmetric septation ### SEQUENCE -M-E-V-T-D-V-R-L-R-R-V-N-T-E-G-R-M-R-A-I-A-S-I-T-L-D-H-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-G-T-R-S-K-I-Q-D-A-V-L-T-E-Y-H-R-L-G-E-L-E-E-V-E-F-E-E-A-G-A-S"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-S-K-L-I-D-S-F-M-K-L-P-G-I-G-P-K-T-A-V-R-L-A-F-F-V-L-D-M-K-E-D-D-V-L-G-F-A-K-A-L-V-N-A-K-R-D-L-A-Y-C-S-V-C-G-H-I-T-D-R-D-P-C-Y-I-C-N-D-S-H-R-D-Q-S-V-V-C-V-V-Q-E-P-K-D-V-I-A-M-E-K-M-K-E-Y-Q-G-V-Y-H-V-L-R-G-A-I-S-P-M-G-G-I-G-P-E-D-I-N-I-P-Q-L-L-K-R-L-H-D-E-T-V-Q-E-V-I-L-A-T-N-P-N-I-E-G-E-A-T-A-M-Y-I-S-R-L-L-K-P-T-G-I-K-V-T-R-I-A-H-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-L-E-G-R-R-E-V"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-R-G-G-M-G-N-M-N-N-M-M-K-Q-M-Q-K-M-Q-K-E-M-A-K-A-Q-E-E-L-G-E-K-T-V-E-G-T-A-G-G-G-M-I-T-V-I-A-N-G-H-K-Q-I-L-E-V-K-V-K-E-E-V-V-D-P-E-D-I-E-M-L-Q-D-L-V-L-A-A-T-N-D-A-L-K-K-A-D-E-L-S-N-S-T-M-G-K-F-T-K-G-L-N-L-P-G-G-M-F"} +{"text": "### FUNCTION Essential cell division protein ### SEQUENCE -M-S-N-L-A-V-K-Y-K-Q-Q-A-Q-E-E-V-Q-I-Q-T-P-P-Q-Q-M-V-Q-P-K-A-K-A-K-I-T-R-I-E-K-L-L-Y-V-A-F-I-G-F-L-L-Y-A-C-V-A-F-I-G-N-K-A-G-L-Y-Q-V-N-V-E-A-A-T-I-E-Q-K-I-V-Q-Q-Q-K-E-N-Q-E-L-Q-A-E-V-E-K-L-S-R-Y-E-R-I-A-E-V-A-K-K-H-G-L-E-I-N-A-N-N-V-K-G-L-K"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-W-S-K-V-K-Y-F-F-F-D-T-P-E-E-K-E-A-A-Q-Y-S-Y-E-K-E-Q-T-D-M-K-K-Q-Q-D-P-P-E-Q-Q-D-V-T-F-P-K-A-Q-P-K-Q-N-V-V-S-I-E-T-A-K-Q-S-S-K-V-V-L-L-E-P-R-T-Y-S-E-A-Q-G-I-A-D-H-L-K-G-R-R-A-V-V-I-N-L-Q-R-M-S-T-D-Q-A-V-R-I-V-D-F-L-S-G-T-V-Y-A-I-G-G-D-I-Q-K-I-G-P-K-T-F-M-C-T-P-E-N-V-D-I-V-G-A-I-S-E-L-F-G-E-E-D-D-T-N-I-K-R-W"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-Q-E-K-A-V-V-L-D-D-Q-M-I-R-R-A-L-T-R-I-S-H-E-I-V-E-R-N-K-G-V-D-N-C-V-L-V-G-I-K-T-R-G-I-F-I-A-Q-R-L-A-E-R-I-G-Q-I-E-G-K-E-M-E-V-G-E-L-D-I-T-L-Y-R-D-D-L-T-L-Q-S-K-N-K-E-P-L-V-K-G-S-D-I-P-V-D-I-T-K-K-K-V-I-L-V-D-D-V-L-Y-T-G-R-T-V-R-A-A-M-D-A-L-M-D-L-G-R-P-S-Q-I-Q-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-S-E-E-R-I-E-V-D-L-Q-E-T-D-Q-Q-D-R-V-S-I-Y-D-K"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-L-N-P-S-I-D-S-L-L-T-K-I-D-S-K-Y-T-L-V-T-V-A-A-K-R-A-R-E-M-Q-L-A-N-N-C-V-V-E-K-P-V-S-H-K-C-V-G-K-A-L-E-E-I-D-M-E-A-L-S-Y-V-P-S-E-D-K-V-T-E"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-V-L-E-I-V-K-H-P-N-E-V-L-E-T-P-C-E-R-V-I-N-F-D-K-K-L-V-K-L-L-K-D-M-H-E-T-M-L-I-A-D-G-V-G-L-A-A-P-Q-V-G-V-S-L-Q-V-A-V-V-D-I-G-D-D-T-G-K-I-E-L-I-N-P-S-I-L-E-K-R-G-E-Q-V-G-P-E-G-C-L-S-F-P-G-L-Y-G-E-V-E-R-A-D-Y-I-K-V-R-A-Q-N-R-R-G-K-V-F-L-L-E-A-E-G-L-L-A-R-A-I-Q-H-E-I-D-H-L-H-G-V-L-F-T-S-K-V-T-R-Y-Y-E-E-N-E-L-E"} +{"text": "### FUNCTION Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism ### SEQUENCE -M-K-K-R-R-S-K-K-E-R-Q-E-L-L-Q-Q-T-I-E-T-N-P-F-I-T-D-E-D-L-A-E-K-F-Q-V-S-I-Q-T-V-R-L-D-R-M-E-L-S-I-P-E-L-R-E-R-I-K-H-V-A-T-K-Q-H-E-E-D-V-K-S-L-P-L-E-E-V-V-G-E-I-I-D-I-E-L-D-R-H-A-I-S-I-F-E-V-K-V-E-H-V-F-K-R-N-Q-I-A-R-G-H-H-L-F-A-Q-A-N-S-L-A-V-A-V-I-D-E-E-L-A-L-T-A-K-S-T-I-R-Y-I-R-P-V-K-L-G-E-R-V-V-A-K-A-R-V-E-D-V-E-N-D-K-G-R-T-V-V-K-V-R-S-F-V-G-E-E-L-V-F-T-G-T-F-E-M-Y-R-S-S-N-Y-S-E-E-G-N-N-L"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-D-V-L-E-R-V-T-K-I-I-V-D-R-L-G-V-E-E-T-E-V-V-P-A-A-S-F-K-E-D-L-G-A-D-S-L-D-V-V-E-L-V-M-Q-L-E-D-E-F-E-M-E-I-S-D-E-D-A-E-K-I-A-T-V-G-D-A-V-T-Y-I-E-S-H-L"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-K-W-F-N-V-G-K-I-V-N-T-H-G-V-K-G-E-I-R-V-V-S-R-T-D-F-P-E-E-R-Y-K-V-G-N-T-L-Y-I-S-N-E-K-G-G-E-P-F-P-V-K-I-T-S-H-R-Q-H-K-T-F-D-L-L-T-F-E-G-Y-G-N-V-N-E-V-E-Q-F-K-G-S-L-L-K-V-P-E-D-Q-L-G-E-L-A-E-G-E-Y-Y-Y-H-E-I-I-G-C-N-V-V-T-E-E-G-E-A-L-G-T-I-K-E-V-L-S-P-G-A-N-D-V-W-V-I-K-R-P-K-G-Q-D-L-L-I-P-Y-I-D-D-V-V-L-Q-V-N-I-E-N-K-L-V-T-I-H-V-T-E-G-L-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-Q-Q-L-I-A-E-I-T-K-G-Q-L-K-T-D-L-P-S-F-R-P-G-D-T-L-R-V-H-V-K-V-V-E-G-T-R-E-R-I-Q-L-F-E-G-V-V-I-K-R-R-G-G-G-I-S-E-T-F-T-V-R-K-I-S-Y-G-V-G-V-E-R-T-F-P-V-H-T-P-R-I-A-K-I-E-V-L-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-N-L-R-G-K-K-A-R-I-K-E-I-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-G-Q-Q-V-L-K-F-S-N-E-K-M-E-K-A-V-A-A-Y-S-R-E-L-A-T-V-R-A-G-R-A-S-A-S-V-L-D-K-V-Q-V-D-Y-Y-G-A-P-T-P-V-V-Q-L-A-N-I-T-V-P-E-A-R-L-L-V-I-Q-P-Y-D-K-T-S-I-G-D-I-E-K-A-I-L-K-A-D-L-G-L-N-P-S-N-D-G-T-V-I-R-I-A-F-P-A-L-T-E-E-R-R-R-D-L-V-K-V-V-K-K-Y-A-E-E-A-K-V-A-V-R-N-V-R-R-D-G-N-D-D-L-K-K-L-E-K-A-G-E-I-T-E-D-D-L-R-G-Y-T-E-D-I-Q-K-E-T-D-K-Y-I-A-K-V-D-E-I-A-K-N-K-E-K-E-I-M-E-V"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-D-K-K-V-T-E-V-V-E-A-F-A-Q-P-I-V-E-E-L-N-L-E-L-V-D-V-E-Y-V-K-E-G-Q-D-W-F-L-R-V-F-I-D-S-E-K-G-V-D-I-E-E-C-G-A-V-S-E-R-L-S-E-A-L-D-K-E-D-P-I-P-H-L-Y-F-L-D-V-S-S-P-G-A-E-R-P-L-K-K-E-K-D-F-Q-Q-A-V-G-K-Q-V-A-I-K-T-Y-E-P-I-D-G-E-K-M-F-E-G-K-M-L-S-Y-D-G-T-T-I-T-L-L-L-T-I-K-T-R-K-K-E-I-Q-I-P-M-D-K-V-A-N-A-R-L-A-V-T-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-L-R-A-N-R-V-G-E-Q-M-K-K-E-L-G-D-I-I-S-R-K-I-K-D-P-R-V-G-F-V-T-V-T-D-V-Q-V-S-R-D-L-Q-I-A-T-V-Y-I-S-V-L-G-D-E-E-Q-K-E-N-T-L-K-G-L-A-K-A-K-G-F-I-R-S-E-I-G-Q-R-I-R-L-R-K-T-P-E-I-S-F-E-F-D-E-S-I-G-Y-G-H-R-I-D-T-L-L-H-E-I-N-K-E-G-K-R-E-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-Q-E-R-K-N-E-I-I-A-Q-F-R-T-H-E-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-E-Q-I-N-T-L-N-E-H-L-R-T-H-K-K-D-H-H-S-R-R-G-L-L-K-M-V-G-K-R-R-N-L-L-T-Y-L-R-N-S-D-I-T-R-Y-R-E-L-I-T-K-L-G-L-R-R"} +{"text": "### FUNCTION Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation Inhibited by the antiholin-like proteins LrgAB In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential ### SEQUENCE -M-K-Y-V-M-L-L-L-Q-V-G-V-L-Y-V-F-S-L-V-G-T-W-I-Q-G-V-F-H-L-S-M-P-G-S-L-I-G-M-L-M-L-F-L-L-L-S-T-R-I-L-P-L-K-W-F-E-E-G-A-E-K-L-L-V-F-L-P-L-F-L-I-P-S-T-T-G-L-M-E-Y-E-S-F-L-F-S-K-G-S-I-I-F-L-L-V-V-I-S-T-V-V-T-L-I-V-S-G-Y-I-S-Q-L-L-V-T-S-K-K"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-K-Q-S-I-N-I-Q-D-Q-F-L-N-Q-L-R-K-E-N-T-F-V-T-L-Y-L-L-N-G-F-Q-L-R-G-L-I-K-G-F-D-N-F-T-V-L-L-E-T-E-G-K-Q-Q-L-I-Y-K-H-A-I-S-T-F-V-P-Q-K-N-V-S-I-E-L-E"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-L-I-P-T-V-I-E-Q-T-N-R-G-E-R-A-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-G-S-A-I-D-D-N-V-A-N-S-I-V-S-Q-L-L-F-L-E-S-Q-D-P-E-K-D-I-H-I-Y-I-N-S-P-G-G-S-I-T-A-G-M-A-I-Y-D-T-M-Q-F-I-K-P-Q-V-S-T-I-C-I-G-M-A-A-S-M-G-A-F-L-L-A-A-G-E-K-G-K-R-Y-A-L-P-N-S-E-A-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-T-E-I-E-I-A-A-K-R-I-L-F-L-R-E-K-L-N-Q-I-L-A-D-R-T-G-Q-P-L-E-V-L-Q-R-D-T-D-R-D-N-F-M-T-A-E-K-A-L-E-Y-G-L-I-D-K-I-F-T-N-R"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-P-K-G-S-G-K-V-I-A-Q-N-K-K-A-F-H-D-Y-F-I-E-E-T-Y-E-A-G-L-V-L-Q-G-T-E-I-K-S-I-R-A-G-R-V-N-L-K-D-A-F-A-R-V-H-N-G-E-V-W-V-H-N-M-H-I-S-T-Y-E-Q-G-N-R-F-N-H-D-P-L-R-T-R-K-L-L-L-H-K-K-E-I-E-K-L-A-G-A-S-K-E-T-G-Y-A-L-V-P-V-R-I-Y-L-K-N-G-F-A-K-M-A-L-G-L-A-K-G-K-K-Q-Y-D-K-R-H-D-L-K-E-K-E-A-K-R-E-I-A-R-A-F-R-D-R-Q-K-M"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-E-A-L-L-V-A-T-G-G-F-F-G-A-I-T-R-F-T-I-S-N-W-F-K-K-R-N-K-T-S-F-P-I-A-T-F-L-I-N-I-T-G-A-F-L-L-G-Y-I-I-G-N-G-V-T-T-G-W-Q-L-L-L-G-T-G-F-M-G-A-F-T-T-F-S-T-F-K-L-E-S-V-Q-L-L-N-R-K-N-F-S-T-F-L-L-Y-L-S-A-T-Y-I-V-G-I-L-F-A-F-L-G-M-K-L-G-G-I"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-R-K-L-I-Y-I-I-V-G-I-A-G-I-L-G-A-L-S-R-Y-Y-L-G-L-T-I-H-E-F-W-H-H-T-F-P-L-A-T-L-L-I-N-L-A-G-C-F-L-L-A-W-L-T-T-Y-I-A-K-L-N-I-L-P-S-D-V-I-T-G-I-G-T-G-F-I-G-S-F-T-T-F-S-T-L-S-V-E-T-I-Q-L-I-N-H-S-E-W-G-I-A-F-L-Y-V-S-C-S-I-L-G-G-L-I-M-S-G-L-G-Y-T-L-G-D-F-L-L-K-K-H-L-T-E-G-D-H-L"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-I-P-N-N-L-R-Y-S-E-E-H-E-W-V-K-T-E-G-N-E-V-V-I-G-I-T-H-F-A-Q-N-E-L-G-D-I-V-F-V-E-L-P-E-V-G-A-T-I-E-A-D-E-P-F-G-S-V-E-S-V-K-T-V-S-E-L-Y-A-P-V-S-G-K-V-V-A-V-N-E-E-L-S-D-Q-P-E-L-V-N-E-S-P-Y-E-G-A-W-M-V-K-V-E-L-S-D-A-S-Q-V-E-K-L-L-T-A-E-K-Y-A-E-M-T-N-Q-D"} +{"text": "### FUNCTION Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation Inhibited by the antiholin-like proteins LrgAB In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential ### SEQUENCE -M-K-W-W-K-L-S-G-Q-I-L-L-L-F-C-F-A-W-T-G-E-W-I-A-K-Q-A-H-L-P-I-P-G-S-I-I-G-I-F-L-L-L-I-S-L-K-F-N-L-V-K-K-E-W-I-Q-D-G-A-D-F-L-L-K-E-L-I-L-F-F-I-P-S-A-V-A-V-I-R-Y-K-D-T-L-S-Q-Y-G-I-D-L-I-L-I-I-M-I-S-T-L-C-V-T-L-V-T-G-L-L-T-E-L-L-L-K-R-K-G-S-V-Q"} +{"text": "### FUNCTION Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization ### SEQUENCE -M-L-L-Q-G-T-H-R-I-G-R-M-A-M-L-L-A-L-A-D-E-N-E-S-P-V-L-S-I-P-K-G-W-K-Y-C-T-G-K-V-G-S-M-N-S-Q-K-V-V-A-A-M-E-T-A-A-K-S-N-Q-V-I-E-T-D-V-Y-R-E-T-H-A-L-Y-H-A-I-M-E-A-L-Y-G-V-T-R-G-Q-I-Q-L-A-D-V-L-R-T-V-G-L-R-F-A-I-V-R-G-T-P-Y-D-G-K-K-E-G-E-W-V-A-V-A-L-Y-G-T-I-G-A-P-V-K-G-S-E-H-E-A-I-G-L-G-I-N-H-I"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-R-I-S-V-E-N-V-K-H-V-A-H-L-A-R-L-A-I-T-D-Q-E-A-E-K-F-Q-K-Q-L-D-A-I-V-T-F-A-E-Q-L-N-E-L-D-T-T-D-V-K-P-T-T-H-V-L-T-M-K-N-V-M-R-E-D-V-P-E-K-G-L-P-V-E-E-V-L-K-N-A-P-D-H-K-D-N-Q-I-R-V-P-A-V-L-E"} +{"text": "### FUNCTION Plays a major role in assembly and budding of virion Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form Inhibits viral transcription and stimulates replication ### SEQUENCE -M-S-L-F-K-R-T-K-K-T-I-L-I-P-P-P-H-L-L-S-G-D-E-D-R-V-T-V-L-N-A-E-G-E-I-K-I-S-G-K-R-P-T-T-L-D-E-K-I-Y-Y-S-M-S-L-A-A-A-I-L-G-G-N-L-H-P-S-F-Q-S-L-T-Y-L-F-Q-Q-E-M-E-F-G-S-T-I-E-K-V-N-F-G-S-R-K-P-A-P-L-T-P-I-R-W-Q-K-P-E-K-C-S-F-R-P-Q-P-L-D-K-K-I-P-P-Q-I-Y-T-V-S-V-E-G-A-T-I-T-F-S-G-R-F-L-F-S-A-S-H-V-G-C-D-D-N-R-V-K-L-A-G-L-D-G-F-I-T-S-P-N-Y-Q-R-V-K-D-Y-Y-A-Q-E-T-V-L-A-L-S-F-E-I-P-T-K-K-G-K"} +{"text": "### FUNCTION Plays an essential role for the viral pathogenicity ### SEQUENCE -M-N-S-K-T-P-S-T-D-I-A-A-L-K-D-L-L-R-Y-K-V-T-V-A-R-H-G-F-L-F-D-D-G-K-I-V-W-S-E-D-G-D-E-A-W-N-R-L-L-V-V-V-G-A-L-R-S-S-N-R-M-S-Q-A-L-F-M-D-M-S-I-T-K-G-D-G-Y-L-L-F-S-D-L-Q-G-T-N-N-L-Q-Y-R-T-P-K-F-R-Q-Y-L-F-P-V-D-E-F-L-P-L-P-R"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-E-N-V-N-T-F-L-E-K-V-L-Y-M-E-E-D-R-G-I-A-D-P-P-L-D-S-L-L-S-R-S-G-S-K-Y-G-L-V-I-Y-A-A-K-R-A-R-Q-I-D-Q-Y-Y-I-D-L-H-E-G-S-F-Y-A-H-V-G-P-L-V-S-V-D-A-D-D-K-S-L-T-V-A-M-R-E-I-A-E-D-K-L-D-L-K-S-S-A-A-E"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-E-E-D-R-G-I-A-D-P-P-L-D-S-L-L-S-R-S-G-S-K-Y-G-L-V-I-Y-A-A-K-R-A-R-Q-I-D-Q-Y-Y-I-D-L-H-E-G-S-F-Y-A-H-V-G-P-L-V-S-V-D-A-D-D-K-S-L-T-V-A-M-R-E-I-A-E-D-K-L-D-L-K-S-S-A-A-E"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-Q-T-A-H-I-G-T-D-I-I-E-I-S-R-I-R-K-A-I-K-A-H-S-Q-R-I-L-N-K-I-F-T-K-R-E-Q-E-Y-C-L-S-L-T-N-P-Y-P-S-F-A-A-R-F-A-A-K-E-A-V-A-K-A-L-G-T-G-I-G-K-V-V-R-W-K-D-I-E-I-L-K-S-S-K-H-P-E-V-Y-L-P-E-R-V-Y-K-E-L-G-I-S-K-V-L-L-S-I-S-H-S-R-E-Y-A-T-A-V-A-V-T-L-I"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-M-S-V-A-L-A-V-I-D-Q-V-E-Q-A-A-Q-Q-A-G-D-V-T-A-V-R-S-V-R-L-Q-V-G-E-L-A-G-V-V-P-D-S-L-S-F-C-F-E-L-A-C-A-G-T-V-L-E-G-A-D-L-V-T-E-E-V-P-G-R-A-R-C-A-P-C-A-R-E-W-S-V-G-M-P-P-R-L-S-C-P-E-C-G-G-A-R-V-D-L-L-S-G-R-E-L-Q-I-V-S-V-H-W-E-D-G-R-T-H-A-Q-T-R-E-P-I-S-E-E-R"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-T-T-A-S-S-K-V-A-I-K-P-L-E-D-R-I-V-V-Q-P-L-D-A-E-Q-T-T-A-S-G-L-V-I-P-D-T-A-K-E-K-P-Q-E-G-V-V-L-A-V-G-P-G-R-F-E-D-G-N-R-L-P-L-D-V-T-V-G-D-V-V-L-Y-S-K-Y-G-G-T-E-V-K-Y-N-G-E-E-Y-L-V-L-S-A-R-D-V-L-A-I-V-E-K"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-Y-G-I-G-T-D-L-V-D-P-A-R-I-A-S-S-L-E-R-Y-G-E-Q-F-A-R-R-V-L-A-D-S-E-W-P-D-Y-L-E-H-I-K-P-A-L-F-L-A-K-R-F-A-A-K-E-A-F-S-K-A-T-G-T-G-L-R-A-P-V-M-F-G-N-M-A-V-Q-H-D-S-Q-G-K-P-Y-F-E-F-Q-Q-E-L-A-E-W-I-G-Q-R-G-I-T-R-H-H-L-S-I-S-D-E-L-T-M-V-S-A-F-V-V-L-E-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-T-I-Q-M-Q-G-E-V-I-E-T-L-P-N-A-T-F-R-I-K-L-E-N-G-H-I-V-L-G-H-I-S-G-K-M-R-M-N-Y-I-R-I-L-P-G-D-K-V-T-V-D-L-T-P-Y-D-L-T-R-A-R-I-T-F-R-T-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-L-L-N-T-K-Q-M-R-L-R-R-A-K-A-T-R-I-K-I-G-N-S-R-Q-F-R-L-S-V-H-K-S-N-N-H-I-Y-A-Q-I-L-D-P-S-S-N-R-V-I-V-S-A-S-T-V-E-A-E-V-K-K-Q-Y-P-S-G-G-T-I-E-A-A-K-Y-V-G-H-L-V-A-K-K-S-I-E-S-Q-I-Y-E-V-A-F-D-R-S-G-F-K-Y-H-G-R-I-K-A-L-A-D-A-A-R-S-A-G-M-K-F"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-R-L-L-E-Y-Y-R-D-T-V-T-K-E-L-T-Q-K-F-N-Y-K-T-V-M-E-V-P-K-I-T-K-I-T-L-N-M-G-V-G-E-A-S-T-D-K-K-I-I-E-N-A-V-S-D-L-E-K-I-S-A-Q-K-P-V-V-T-K-A-R-K-S-I-A-T-F-K-V-R-Q-G-Y-P-V-G-C-K-V-T-L-R-G-V-K-M-Y-E-F-L-D-R-L-V-N-V-A-I-P-R-I-R-D-F-R-G-I-Q-V-K-G-F-D-G-R-G-N-F-N-M-G-I-K-E-Q-I-I-F-P-E-I-D-Y-D-K-I-D-K-V-R-G-L-N-I-T-V-T-T-T-A-K-T-D-Q-E-A-R-A-L-L-S-A-F-K-F-P-F-K-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-K-I-R-K-G-D-S-V-I-V-I-A-G-K-D-K-G-K-Q-S-T-V-I-R-F-Q-S-T-E-R-V-I-V-R-E-V-N-K-V-K-S-H-I-K-P-N-P-N-R-N-I-A-G-G-I-V-E-T-E-K-P-L-H-I-S-N-I-A-I-F-N-P-E-K-N-K-A-D-R-V-G-F-R-F-N-E-S-G-N-K-V-R-Y-F-K-S-D-G-T-L-I-D-S"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-I-A-G-L-L-L-E-K-H-P-P-L-V-L-V-D-V-N-G-I-G-Y-E-I-D-V-P-M-S-T-F-C-R-L-P-G-I-G-E-Q-V-T-L-H-T-H-F-W-V-R-E-D-A-H-L-L-F-G-F-M-T-E-P-E-R-V-L-F-R-Q-L-T-K-I-S-G-I-G-A-R-T-G-L-A-I-L-S-G-L-S-V-N-D-L-H-Q-I-V-V-S-Q-D-S-T-R-L-T-R-I-P-G-I-G-K-K-T-A-E-R-L-L-L-E-L-R-D-K-I-S-P-A-I-T-L-P-E-T-G-T-A-M-A-S-S-T-D-K-D-I-L-N-A-L-S-A-L-G-Y-N-D-R-E-A-N-W-A-V-G-Q-L-S-E-G-V-T-V-S-D-G-I-M-Q-S-L-R-L-L-S-K-A-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-G-T-I-F-H-L-D-I-V-S-A-E-E-S-I-Y-S-G-P-A-E-F-I-V-A-P-A-V-M-G-E-V-G-I-F-P-Q-H-T-P-M-L-T-R-I-K-S-G-V-V-R-V-K-A-P-L-Q-D-D-E-E-V-Y-V-S-G-G-M-L-E-V-Q-P-D-V-V-T-I-L-A-D-T-A-V-R-G-K-D-L-D-E-A-K-A-L-E-A-K-R-K-A-E-E-I-M-K-N-K-I-S-E-I-E-Y-A-R-A-Q-A-E-L-I-E-A-T-A-Q-L-A-A-I-Q-K-L-R-K-R-G-H"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-K-G-I-G-I-D-A-V-E-L-S-R-I-K-P-I-V-E-K-Q-G-S-F-I-Q-R-V-L-T-P-N-E-L-T-L-F-E-K-L-S-T-K-R-Q-I-E-F-L-A-G-R-F-A-C-K-E-A-F-S-K-A-W-G-T-G-I-G-K-V-G-L-Q-D-I-E-V-L-T-E-K-T-G-A-P-Y-V-A-N-S-P-H-N-G-K-V-F-V-S-I-T-H-T-E-T-M-A-I-A-Q-I-V-L-E-S-E"} +{"text": "### FUNCTION General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases ### SEQUENCE -M-K-T-I-L-P-E-V-L-F-A-A-F-A-T-T-S-A-W-A-A-E-S-V-Q-P-L-E-K-I-A-P-Y-P-Q-A-E-T-G-M-K-R-Q-V-I-Q-L-T-P-Q-E-D-E-S-T-L-K-V-E-L-L-I-G-Q-T-L-E-V-D-C-N-L-H-R-L-G-G-K-L-E-S-K-T-L-E-G-W-G-Y-D-Y-Y-V-F-D-K-V-S-S-P-V-S-T-M-M-A-C-P-D-G-K-K-E-K-K-F-V-T-A-Y-L-G-D-A-G-M-L-R-Y-N-S-K-L-P-I-V-V-Y-T-P-D-N-V-D-V-K-Y-R-V-W-K-A-E-E-K-I-D-N-A-E-V-R"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-K-I-N-Q-P-A-V-A-G-T-L-E-S-G-D-V-M-I-R-I-A-P-L-D-T-Q-D-I-D-L-Q-I-N-S-S-V-E-K-Q-F-G-D-A-I-R-T-T-I-L-D-V-L-A-R-Y-N-V-R-G-V-Q-L-N-V-D-D-K-G-A-L-D-C-I-L-H-A-R-L-E-A-L-L-A-R-A-S-G-I-P-A-L-P-W-E-D-C-Q"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-P-K-K-T-T-K-K-G-G-P-Q-K-R-P-S-A-E-K-R-I-L-T-A-Q-K-R-Y-L-I-N-Q-S-F-K-S-K-A-K-T-M-M-K-K-F-E-A-A-L-K-A-G-D-Q-S-S-I-T-S-G-L-Q-L-V-Y-S-V-A-D-K-A-V-K-R-G-I-F-K-N-N-K-A-A-R-I-K-S-R-A-T-L-R-A-N-V-K-I"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-T-F-K-G-V-A-S-A-K-D-M-R-V-A-I-V-G-A-C-F-N-G-P-I-A-D-A-L-V-S-G-A-Q-Q-T-F-L-D-L-G-G-A-E-D-M-L-T-V-V-R-V-P-G-S-F-E-I-P-C-T-L-K-K-L-L-T-S-G-V-K-Y-D-A-I-V-A-C-G-V-L-I-K-G-E-T-T-H-Y-D-H-I-A-D-Q-V-S-A-R-I-S-E-L-S-L-E-F-N-L-P-I-T-F-S-V-I-T-A-P-C-I-D-S-A-W-Q-R-A-G-I-K-G-S-N-L-G-I-S-G-M-K-T-A-L-E-M-A-D-L-F-K-K-L"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-R-V-S-T-S-E-F-R-V-G-L-R-I-E-I-D-G-Q-P-Y-L-I-L-Q-N-D-F-V-K-P-G-K-G-Q-A-F-N-R-I-K-V-K-N-F-L-T-G-R-V-I-E-R-T-F-K-S-G-E-S-V-E-T-A-D-V-R-E-Q-Q-M-R-F-L-Y-S-D-Q-E-G-A-T-F-M-D-D-E-T-F-E-Q-E-M-I-F-W-D-K-I-E-N-I-R-Q-W-L-L-E-D-T-I-Y-T-L-V-L-Y-N-G-N-V-I-G-V-E-P-P-I-F-M-E-L-T-I-A-E-T-A-P-G-V-R-G-D-T-A-S-G-R-V-L-K-P-A-V-T-N-T-G-A-K-I-M-V-P-I-F-I-E-E-G-E-V-V-K-I-D-T-R-T-G-S-Y-E-S-R-V-S-K"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-H-R-S-T-L-P-K-Y-A-R-V-L-K-R-K-Q-F-L-Y-I-S-R-A-G-S-H-C-Q-G-S-Q-V-I-F-H-V-A-P-S-R-Y-S-G-C-C-K-L-G-I-T-V-S-K-K-F-G-K-A-H-K-R-N-Y-F-K-R-I-V-R-E-A-F-R-K-K-R-H-S-L-P-A-C-Q-I-V-V-M-P-K-N-K-Q-Q-P-K-F-E-D-L-L-Q-D-F-A-Q-Q-I-P-E-A-L-S-S-K-L-A-K-N-K-P-T-T-G-V-E-Y-S-P-K-N-E-K-C-E-S-V-L-P"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-A-V-A-R-E-N-K-R-R-R-L-V-E-A-N-Y-K-K-R-S-E-L-R-N-I-A-K-S-L-T-A-S-E-E-E-K-E-N-A-R-V-A-L-N-K-M-R-R-D-T-A-H-I-R-L-H-N-R-C-L-L-T-G-R-P-R-G-Y-L-R-K-F-A-I-S-R-I-C-F-R-E-M-A-S-M-G-E-I-P-G-V-I-K-A-S-W"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-E-L-V-V-T-S-R-E-T-D-K-K-S-L-L-K-K-I-R-Q-T-G-G-I-P-A-V-I-Y-S-G-G-K-S-L-A-N-I-V-V-D-A-H-V-F-G-K-F-L-S-S-L-E-S-G-A-L-S-S-T-I-F-S-L-S-Y-E-G-R-T-I-K-A-L-V-K-D-I-Q-Y-Q-V-T-S-Y-R-V-I-H-L-D-F-E-E-L-I-E-D-R-D-V-K-L-N-I-P-I-R-C-I-N-A-V-D-C-V-G-V-K-L-G-G-S-L-R-Q-V-I-R-A-M-R-V-V-C-K-P-K-D-I-V-P-C-L-E-L-D-V-R-S-L-G-L-S-Q-T-R-K-L-A-D-I-N-I-P-A-G-L-R-P-I-T-P-L-K-E-V-V-V-T-V-S-R-R"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-M-L-I-V-A-I-G-N-P-G-R-Q-Y-T-W-T-R-H-N-I-G-F-L-C-A-D-K-L-L-Q-G-F-P-E-A-Q-F-K-E-A-R-K-L-F-S-D-I-A-K-V-E-S-P-Q-G-S-M-V-F-I-K-P-R-T-Y-V-N-L-S-G-K-A-V-S-A-V-K-E-Y-Y-G-I-P-I-D-R-I-L-V-L-A-D-D-V-N-H-P-F-G-N-V-R-L-R-Q-N-A-G-G-G-G-H-K-G-I-K-S-I-T-Q-S-L-G-S-N-D-Y-W-Q-L-R-L-G-I-G-R-P-Q-R-E-D-I-E-L-S-D-F-V-L-G-Q-F-T-E-E-E-Q-I-G-I-Q-S-L-F-I-E-A-S-A-L-F-S-Q-W-C-S-G-T-Q-T-A"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-K-E-K-K-A-Q-L-Y-E-G-A-Y-V-F-S-V-T-L-S-E-E-A-R-R-K-A-L-E-K-V-T-S-G-I-T-N-Y-G-G-E-I-L-K-I-H-D-Q-G-R-K-K-L-A-Y-T-I-R-G-A-R-E-G-Y-Y-Y-L-I-Y-F-T-V-V-P-G-V-I-A-E-L-W-K-E-Y-H-L-N-E-D-L-L-R-F-L-T-L-K-A-D-A-V-K-E-V-L-E-F-A-S-L-P-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-N-K-P-V-H-N-N-E-H-R-R-K-R-F-N-K-K-C-P-F-V-S-A-G-W-K-T-I-D-Y-K-D-T-E-T-L-K-K-F-I-T-E-R-G-K-I-L-P-R-R-I-T-G-V-S-S-R-F-Q-G-T-L-T-L-A-I-K-R-A-R-H-I-G-L-L-P-F-V-A-E-D"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-Q-Q-L-L-L-L-E-D-V-D-G-L-G-R-S-G-D-I-V-T-A-R-P-G-Y-V-R-N-Y-L-M-P-Q-K-K-A-V-I-A-G-A-G-T-L-R-L-Q-A-K-L-K-E-E-R-L-L-R-A-A-E-D-R-A-E-S-E-K-L-A-E-A-L-R-D-V-I-L-E-F-Q-V-R-V-D-P-D-N-N-M-Y-G-S-V-T-I-S-D-I-I-D-E-A-A-K-K-N-I-I-L-T-R-K-N-F-P-H-S-H-Y-A-I-K-N-L-G-K-K-S-V-P-L-K-L-K-E-D-V-T-A-T-L-F-V-E-V-S-S-E-S-S-Y-V-A-V-L-N-Q-Q-P-T-Q-E-E-P-A-A-E-E-S-N"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-A-L-N-L-K-I-N-R-Q-I-R-A-P-K-V-R-L-I-G-S-S-G-E-Q-L-G-I-L-N-T-K-D-A-L-D-L-A-R-E-A-D-L-D-L-V-E-V-A-S-N-S-E-P-P-V-C-K-I-M-D-Y-G-K-Y-R-Y-D-L-T-K-K-E-K-D-S-K-K-A-Q-H-Q-V-R-I-K-E-V-K-L-K-P-N-I-D-E-G-D-F-S-T-K-L-K-Q-A-R-A-F-I-E-K-G-N-K-V-K-I-T-C-M-F-R-G-R-E-L-A-Y-P-E-H-G-H-R-V-V-Q-K-M-S-Q-G-L-E-D-I-G-F-M-E-S-E-P-K-L-N-G-R-S-L-I-C-V-M-A-P-G-T-V-K-T-K-K-K-Q-D-K-I-N-A-Q-D-E-K-Q"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-A-T-G-S-V-A-S-R-R-R-R-K-R-V-L-K-Q-A-K-G-F-W-G-D-R-K-G-H-F-R-Q-S-R-S-S-V-M-R-A-M-A-F-N-Y-M-H-R-K-D-R-K-G-D-F-R-S-L-W-I-A-R-L-N-V-A-S-R-I-N-G-L-S-Y-S-R-L-I-N-G-L-K-C-A-G-I-D-L-N-R-K-M-L-S-E-M-A-I-H-N-P-M-G-F-A-E-V-A-N-Q-A-K-K-A-L-E-A-T-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-D-K-G-T-K-E-E-I-T-K-K-F-Q-L-H-E-K-D-T-G-S-A-D-V-Q-I-A-I-L-T-E-H-I-T-E-L-K-E-H-L-K-R-S-P-K-D-Q-N-S-R-L-A-L-L-K-L-V-G-Q-R-R-K-L-L-E-Y-L-N-S-T-D-T-E-R-Y-K-N-L-I-T-R-L-N-L-R-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-K-E-D-T-I-V-L-E-G-R-V-Q-E-L-L-P-G-M-H-F-K-I-L-L-E-N-G-M-P-V-T-A-H-L-C-G-K-M-R-M-S-N-I-R-L-L-V-G-D-R-V-T-V-E-M-S-A-Y-D-L-T-K-A-R-V-V-Y-R-H-R"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-S-N-K-K-V-I-K-L-I-K-L-Q-I-P-G-G-K-A-N-P-A-P-P-I-G-P-A-L-G-A-A-G-V-N-I-M-G-F-C-K-E-F-N-A-A-T-Q-D-R-P-G-D-L-L-P-V-V-I-T-V-Y-S-D-K-T-F-T-F-I-T-K-Q-P-P-V-S-S-L-I-K-K-A-L-N-L-E-S-G-S-K-I-P-N-R-N-K-V-G-K-L-T-Q-A-Q-V-T-A-I-A-E-Q-K-M-K-D-M-D-V-V-L-L-D-S-A-K-R-M-V-E-G-T-A-R-S-M-G-I-D-V-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-K-E-E-K-K-L-L-L-Q-E-V-E-E-K-I-S-A-S-Q-G-F-I-L-L-R-Y-L-G-F-S-A-A-Y-S-R-E-F-R-N-S-L-S-G-V-S-A-E-F-E-V-L-K-K-R-I-F-F-K-A-I-E-N-S-G-F-E-I-D-S-S-D-T-G-G-H-L-G-V-V-F-A-Y-D-D-A-V-S-A-A-K-Q-V-L-D-F-N-K-Q-H-N-D-S-L-V-F-L-A-G-R-I-D-S-A-N-L-S-G-K-E-V-E-A-V-A-K-L-P-S-M-K-E-L-R-Q-Q-V-V-G-L-L-A-A-P-M-S-Q-V-V-G-I-M-G-S-A-L-S-G-V-I-S-C-I-D-Q-K-T-Q-K-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-T-T-Q-S-L-E-T-L-V-E-T-L-S-N-L-T-V-L-E-L-A-A-L-K-K-L-L-E-D-K-W-D-V-T-A-A-A-P-M-M-A-V-A-A-G-A-A-V-G-G-D-A-A-P-A-E-S-T-E-F-A-V-I-L-E-D-V-P-A-D-K-K-I-G-V-L-K-V-V-R-E-V-T-G-L-A-L-K-E-A-K-E-M-T-E-G-L-P-K-T-V-K-E-K-T-S-K-S-D-A-E-D-T-V-K-K-L-Q-D-A-G-A-K-A-S-F-K-G-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-G-N-L-I-K-E-L-Q-D-E-Q-L-R-K-E-A-L-T-D-F-R-V-G-D-T-I-R-V-A-T-K-I-V-D-G-G-K-E-R-T-Q-V-F-Q-G-T-V-M-A-R-R-G-G-G-A-G-E-T-V-A-L-H-R-V-A-Y-G-E-G-M-E-K-S-F-L-L-H-S-P-K-I-V-G-I-E-V-V-K-R-G-K-V-S-R-A-R-L-Y-Y-L-K-G-K-T-G-K-A-A-K-V-K-E-Y-I-G-P-R-A-P-K"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-N-P-K-N-K-K-E-K-T-F-L-G-I-D-Y-G-Q-R-R-I-G-L-A-Y-A-A-S-P-L-F-I-S-L-P-I-G-C-I-E-A-G-N-T-V-E-A-T-A-K-I-L-F-N-I-I-Q-E-R-S-V-S-C-V-V-L-G-N-P-I-P-M-Q-K-G-Q-K-S-A-L-Q-E-E-I-T-K-L-S-S-L-I-Q-E-S-C-G-V-E-V-I-L-W-D-E-R-L-S-S-A-Q-A-E-R-M-L-K-G-D-C-G-L-S-R-K-K-R-K-G-K-T-D-T-I-A-A-T-L-I-L-T-S-F-L-E-S-S-P-P-K-I-F-L-K-K-T-C-P-K-P-P-V-R"} +{"text": "### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-I-R-F-L-R-N-N-A-L-Y-F-A-W-L-I-C-S-T-G-T-V-M-S-I-Y-Y-S-Y-L-L-N-I-E-P-C-V-L-C-Y-Y-Q-R-I-C-L-F-P-L-S-I-I-L-G-I-A-T-Y-R-E-D-N-L-V-K-I-Y-A-L-P-L-S-I-T-G-M-V-I-A-V-Y-Q-I-C-L-Q-E-I-S-G-M-T-I-D-I-C-G-R-V-S-C-S-T-K-L-F-V-F-G-F-I-T-V-P-M-A-S-A-L-A-F-C-A-I-S-C-L-L-I-L-S-G-S-K-K-K"} +{"text": "### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-A-Q-E-S-N-E-N-G-W-G-D-F-L-E-L-C-S-K-I-K-T-P-E-A-F-H-D-F-F-A-L-F-L-T-F-G-E-R-E-S-M-A-S-R-F-L-I-V-Q-A-L-L-A-E-Q-L-T-Q-R-E-I-A-Q-K-Y-G-V-S-I-A-Q-I-T-R-G-S-N-A-L-K-A-I-D-P-K-F-K-E-F-L-K-N-L-N-R-K-Y-G-N-Q"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-L-S-S-Q-L-S-V-G-M-F-I-S-T-K-D-G-L-Y-K-V-V-A-V-S-K-V-T-G-N-K-G-E-S-F-I-K-A-S-L-K-A-A-D-S-D-V-I-V-E-R-N-F-K-I-G-Q-E-I-K-E-A-Q-F-E-S-R-N-L-E-Y-L-Y-I-E-D-E-N-F-L-F-L-D-L-G-N-Y-E-K-I-Y-I-S-K-E-I-M-K-D-N-F-L-F-L-K-A-G-V-T-V-S-A-M-V-Y-D-D-V-V-F-S-I-E-L-P-H-F-L-E-L-M-V-S-K-T-D-F-P-G-D-S-L-L-I-T-G-G-T-K-K-A-L-L-E-T-G-V-E-I-T-V-P-P-F-V-E-I-G-D-I-I-K-I-D-T-R-T-C-E-Y-I-Q-R-V"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-K-N-V-A-L-D-K-A-L-K-E-I-L-N-E-E-G-A-S-T-Q-E-E-I-C-E-K-L-S-S-L-G-I-A-T-T-Q-S-S-V-S-R-W-L-K-K-V-H-A-I-K-I-P-G-D-K-G-A-R-Y-S-L-P-P-S-I-D-D-S-S-I-K-H-L-V-F-S-I-R-H-N-S-S-L-I-V-I-R-T-A-P-G-S-A-S-W-I-A-S-L-I-D-N-K-F-A-E-S-I-L-G-T-L-A-G-D-D-T-I-F-I-T-P-I-T-E-S-T-I-S-L-T-A-K-D-I-E-N-F-L-L-V-F-S-E"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-E-K-R-K-D-T-K-T-T-I-A-K-A-S-D-A-Q-N-K-S-W-Y-V-I-D-A-T-G-K-T-L-G-R-L-S-S-E-V-A-K-I-L-R-G-K-H-K-V-T-Y-T-P-H-I-A-M-G-D-G-V-I-V-I-N-A-E-K-V-H-L-T-G-A-K-K-G-Q-K-I-Y-R-Y-Y-T-G-Y-I-S-G-M-R-E-I-P-F-E-N-M-L-A-K-K-P-S-Y-I-I-E-H-A-I-K-G-M-M-P-K-T-R-L-G-K-R-Q-L-K-S-L-R-I-L-K-G-D-C-Y-K-T-F-E-A-Q-K-P-I-L-L-D-V"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-L-E-D-D-V-K-S-I-I-V-E-Q-L-G-V-D-A-S-E-V-N-E-N-S-S-F-I-E-D-L-N-A-D-S-L-D-L-T-E-L-I-M-T-L-E-E-K-F-N-F-E-I-S-E-Q-D-A-E-Q-L-R-T-V-G-D-V-I-T-Y-I-K-T-R-Q-G"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-L-K-Y-P-D-Y-L-S-K-L-I-S-L-L-R-K-L-P-G-I-G-F-K-T-A-E-K-L-A-F-E-L-L-D-W-D-Q-D-Q-L-E-A-M-G-Q-A-F-S-E-V-S-A-A-R-S-H-C-S-T-C-F-C-L-K-N-L-P-E-S-N-C-E-F-C-Q-N-N-R-D-T-S-T-L-C-I-V-A-T-P-K-D-I-F-S-L-E-R-S-Q-I-F-K-G-H-Y-Y-V-L-G-T-L-L-S-P-I-T-G-K-H-I-D-V-E-R-I-G-L-L-K-Q-R-I-E-F-L-K-P-Q-E-I-I-L-A-L-D-A-T-L-E-G-D-A-T-A-L-F-L-K-Q-E-L-A-F-S-S-A-S-I-S-R-L-A-L-G-L-P-I-G-L-S-F-D-Y-V-D-S-G-T-L-A-R-A-F-S-G-R-N-P-Y"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-T-E-N-R-R-I-K-K-V-N-S-L-L-R-E-A-I-A-N-V-I-L-K-D-V-K-H-P-K-I-S-N-Q-W-I-T-V-T-R-V-C-L-S-K-D-L-H-S-A-R-V-Y-V-S-I-M-P-H-E-N-T-S-A-E-T-L-D-A-L-K-A-S-A-G-F-I-A-Y-K-A-S-K-G-V-V-L-K-Y-F-P-E-I-H-F-Y-I-E-D-I-F-S-P-Q-D-H-I-E-N-L-L-W-K-I-R-E-Q-D-K-N"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-S-K-E-I-V-S-N-R-K-A-L-R-N-Y-E-V-L-D-T-L-E-A-G-V-V-L-T-G-T-E-I-K-S-L-R-D-H-G-G-N-L-G-D-A-Y-V-A-I-S-K-G-E-A-W-L-L-N-A-S-I-A-P-Y-R-F-G-N-I-Y-N-H-E-E-R-R-K-R-K-L-L-L-H-R-Y-E-I-R-K-L-E-G-R-V-A-Q-K-G-I-T-I-I-P-L-G-M-F-L-S-R-G-Y-V-K-I-R-L-G-C-C-R-G-K-K-A-H-D-K-R-Q-T-I-I-A-R-E-K-Q-R-E-V-E-S-A-M-K-R-Y-R"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-I-V-C-E-L-E-S-G-A-D-L-P-E-Y-A-T-E-G-A-S-G-A-D-L-R-A-H-I-E-E-P-I-A-V-L-P-G-Q-R-V-L-I-P-T-G-I-K-M-Q-I-P-Q-G-Y-E-V-Q-V-R-P-R-S-G-L-A-L-K-H-G-I-M-V-V-N-S-P-G-T-I-D-A-D-Y-R-G-E-V-C-I-I-L-A-N-F-G-E-S-T-F-I-I-E-P-K-M-R-I-A-Q-A-V-V-A-P-V-V-Q-A-K-F-I-V-V-D-Q-E-E-G-L-T-A-T-S-R-G-S-R-G-F-G-H-T-G-E-K"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-G-S-G-Y-A-K-K-K-K-E-A-K-I-M-E-Q-Q-F-L-E-M-E-A-S-L-E-Q-K-R-Y-E-G-Q-A-G-N-G-L-V-S-V-V-I-N-G-K-C-D-I-V-S-I-K-V-Q-P-T-C-L-D-P-E-E-P-E-V-V-E-D-L-F-R-S-A-F-K-E-A-K-E-A-M-D-K-E-M-S-V-M-R-A-G-M-P-F"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-R-E-L-E-Y-Y-G-S-H-I-L-R-R-K-A-D-I-I-P-E-I-T-D-A-T-R-Q-L-V-Q-D-M-Y-E-T-M-V-A-H-K-G-V-G-L-A-A-P-Q-V-G-E-S-L-S-L-F-V-M-C-V-E-G-E-T-E-E-G-D-L-I-F-C-D-F-P-K-V-Y-I-N-P-V-L-S-N-P-S-E-D-L-V-I-G-R-E-G-C-L-S-I-P-G-L-R-A-D-V-Y-R-P-Q-S-I-T-V-T-A-V-N-L-D-G-Q-E-F-T-E-H-L-E-G-F-P-A-R-I-I-M-H-E-N-D-H-L-H-G-V-L-Y-I-D-K-M-E-E-P-K-D-I-K-K-F-K-A-S-L-E-K-I-R-R-R-Y-H-A-H-V-K-P-E-D-R-A-S"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-E-E-I-P-F-E-N-A-M-A-R-L-E-E-I-V-D-L-M-N-Q-P-S-T-S-L-D-S-S-L-K-L-Y-E-E-A-D-A-L-M-R-I-C-E-S-R-I-R-K-A-E-D-R-V-R-E-L-S-E-K-R-N-E-T-L-L-S-E-E-E-S-C-T-H"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-D-S-S-N-E-H-E-T-E-N-P-S-L-P-I-P-D-N-E-I-Q-D-L-Q-Q-E-I-A-T-L-K-A-E-L-K-E-K-N-D-K-Y-L-M-V-L-A-E-S-E-N-A-R-K-R-M-Q-K-E-R-Q-E-M-M-Q-Y-A-V-E-N-A-L-I-D-F-L-V-P-I-E-S-M-E-K-A-L-G-F-A-S-Q-M-S-D-E-V-K-N-W-A-L-G-F-N-M-I-L-Q-Q-F-K-Q-V-F-E-E-K-G-I-V-E-Y-S-S-V-G-Q-K-F-N-P-F-L-H-E-A-V-E-T-E-E-T-T-K-V-P-E-G-T-I-V-E-E-F-S-K-G-Y-K-I-G-E-R-P-I-R-V-A-K-V-K-V-A-K-A-P-A-P-Q-E-K-E-E-V-E-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-K-K-V-S-I-Q-V-C-I-S-N-K-Q-N-D-V-P-I-R-I-Q-S-A-K-K-L-V-L-Y-C-L-Q-H-W-E-V-H-T-D-Q-V-Y-I-Y-F-L-D-D-E-S-L-A-Q-L-H-D-E-V-F-S-D-P-S-L-T-D-T-I-T-L-P-I-D-S-P-G-T-S-S-Q-P-H-I-L-G-E-A-F-I-S-P-K-A-A-I-R-F-L-K-D-R-A-E-D-S-D-L-L-Y-E-E-I-S-R-Y-V-I-H-S-L-L-H-M-L-G-Y-D-D-Q-T-P-E-E-R-K-K-M-R-V-K-E-N-Q-A-L-C-M-L-R-E-K-H-A-L-L-S-D"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-P-D-G-E-V-N-K-L-R-D-V-I-D-K-K-I-L-D-A-R-R-V-F-F-S-E-P-V-T-D-K-S-A-A-D-A-I-K-K-L-W-Y-L-E-L-S-H-P-G-Q-P-I-V-F-V-I-N-S-P-G-G-S-V-D-A-G-F-A-V-W-D-Q-I-K-M-M-T-S-P-V-T-T-V-V-T-G-L-A-A-S-M-G-S-V-L-S-L-C-A-A-P-G-R-R-F-A-T-P-H-S-R-I-M-I-H-Q-P-S-I-G-G-P-I-T-G-Q-A-T-D-L-D-I-H-A-R-E-I-L-K-T-K-K-R-I-V-D-V-Y-L-E-A-T-G-Q-P-R-E-V-I-E-K-A-I-D-R-D-M-W-M-T-A-D-E-A-K-D-F-G-L-L-D-G-I-L-F-S-F-D-D-L"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Q-C-P-F-C-N-H-G-E-L-K-V-I-D-S-R-N-A-P-E-A-N-A-I-K-R-R-R-E-C-L-N-C-G-Q-R-F-T-T-F-E-T-V-E-L-T-L-Q-V-L-K-R-D-G-R-Y-E-N-F-Q-E-S-K-L-I-N-G-L-N-A-A-S-S-H-T-R-I-G-Q-D-Q-V-H-A-I-A-S-N-V-K-S-E-L-L-G-K-Q-N-R-E-I-S-T-K-E-I-G-E-L-V-M-K-Y-L-K-K-A-D-M-I-A-Y-I-R-F-A-C-V-Y-R-R-F-K-D-V-G-E-L-M-E-V-L-L-S-A-T-P-D-M-E-K"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-K-S-Y-A-I-I-Q-T-G-S-K-Q-Y-Q-V-S-E-G-D-V-I-D-V-E-L-L-D-G-I-S-E-G-Q-E-I-V-F-D-Q-V-L-F-T-F-D-G-S-K-V-S-L-G-T-P-I-V-K-D-A-V-V-K-G-Q-L-L-S-Q-V-R-G-E-K-V-T-A-Y-K-Y-K-R-R-K-N-Y-H-R-K-T-G-H-R-Q-N-Y-L-R-V-K-I-S-N-L-V-I"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-Q-Q-K-Q-K-I-R-I-R-L-K-G-F-D-Q-G-Q-L-D-R-S-T-A-D-I-V-E-T-A-K-R-T-G-A-R-V-A-G-P-I-P-L-P-T-K-R-E-V-Y-T-V-L-R-S-P-H-V-D-K-K-S-R-E-Q-F-E-I-R-T-H-K-R-L-I-D-I-L-D-P-T-G-K-T-I-D-A-L-K-M-L-A-L-P-A-G-V-D-I-K-I-K-A-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-A-A-E-K-K-V-I-P-A-D-P-I-Y-G-S-V-T-L-E-R-F-I-N-K-V-M-M-H-G-K-K-S-I-A-R-K-I-V-Y-S-A-L-E-R-F-S-K-K-I-G-A-E-N-V-L-E-A-F-K-E-A-L-E-N-A-K-P-L-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-A-A-G-R-R-D-C-L-A-M-K-W-I-I-N-N-A-R-N-K-P-G-K-C-M-E-V-G-L-A-T-E-L-I-D-C-F-N-K-Q-G-A-T-I-K-K-R-E-D-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-K-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-I-R-K-K-R-Q-S-S-A-S-R-K-K-S-P-A-L-Q-K-C-P-Q-R-R-G-V-C-L-Q-V-K-T-K-T-P-K-K-P-N-S-A-L-R-K-V-A-W-V-R-L-S-N-G-Q-E-V-I-A-Y-I-G-G-E-G-H-N-L-Q-E-H-S-I-V-L-V-Q-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-C-A-A-V-K-N-R-K-Q-S-R-S-R-Y-G-A-K-R-P-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-V-K-H-Q-T-Q-K-K-G-V-K-R-K-Q-L-K-N-I-P-S-G-V-V-H-V-K-A-T-F-N-N-T-I-V-S-I-T-D-P-A-G-N-T-I-S-W-A-S-A-G-K-V-G-Y-S-G-S-R-K-S-S-A-F-A-A-T-M-A-A-Q-D-A-A-K-N-A-M-N-S-G-L-K-E-V-E-V-C-L-K-G-T-G-A-G-R-E-S-A-V-R-A-L-I-A-S-G-L-V-V-S-V-I-R-D-E-T-P-V-P-H-N-G-C-R-P-R-K-R-R-R-V"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-I-K-L-E-S-L-Q-D-P-S-P-R-K-R-R-T-K-L-L-G-R-G-P-S-S-G-H-G-K-T-S-C-R-G-H-K-G-D-G-S-R-S-G-Y-K-R-R-F-G-Y-E-G-G-G-V-P-L-Y-R-R-V-P-T-R-G-F-S-H-K-R-F-D-K-C-V-E-E-I-T-T-Q-R-L-N-V-L-F-N-E-G-E-E-I-T-L-D-A-L-K-E-K-R-A-I-D-K-H-A-I-R-V-K-V-I-V-K-G-E-L-E-K-T-F-I-W-K-D-A-N-V-V-L-S-Q-G-V-R-N-L-I-G-V-A"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-T-L-S-K-N-S-H-K-E-D-Q-L-E-E-K-V-L-V-V-N-R-C-S-K-V-V-K-G-G-R-K-F-S-F-S-A-L-I-L-V-G-D-G-K-G-R-L-G-Y-G-F-A-K-A-N-E-L-T-D-A-I-R-K-G-G-E-A-A-R-K-N-L-I-T-I-E-S-L-E-S-G-S-I-P-H-E-V-L-V-D-Q-D-G-A-Q-L-L-L-K-P-A-K-S-G-T-G-I-V-A-G-S-R-I-R-L-I-L-E-M-A-G-V-K-N-I-V-A-K-S-L-G-S-N-N-P-M-N-Q-V-K-A-A-F-K-A-L-L-S-L-S-S-R-K-D-V-L-Q-R-R-R-V-T-H-D"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-E-N-S-L-F-K-K-S-E-K-K-V-H-R-A-L-R-V-R-K-V-L-R-G-S-S-L-K-P-R-L-C-V-V-K-T-N-K-H-I-Y-V-Q-L-I-D-D-S-I-G-K-T-L-A-S-V-S-T-M-A-K-S-N-K-A-S-G-L-I-K-K-N-Q-D-V-A-K-T-L-G-T-Q-I-A-E-I-G-K-S-L-Q-V-D-R-V-V-F-D-R-G-P-F-K-Y-H-G-I-I-A-M-V-A-D-G-A-R-E-G-G-L-Q-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-K-A-R-D-P-I-V-L-P-Q-G-V-E-V-S-I-Q-N-N-E-I-L-V-K-G-P-K-G-S-L-K-Q-V-L-A-P-E-V-V-V-D-I-K-D-R-E-V-F-V-H-A-A-P-H-V-V-D-R-P-S-R-M-Q-G-L-F-W-A-L-I-S-N-M-V-Q-G-V-N-T-G-F-E-K-R-L-E-M-I-G-V-G-F-R-A-A-V-Q-G-S-V-L-D-L-S-I-G-V-S-H-P-T-K-M-P-I-P-A-E-L-Q-V-S-V-E-K-N-T-L-I-S-V-K-G-I-N-K-Q-L-V-G-E-F-A-A-S-I-R-A-K-R-R-P-E-P-Y-K-G-K-G-I-R-Y-E-N-E-Y-V-R-R-K-A-G-K-A-A-K-T-G-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-M-T-S-D-T-I-A-D-L-L-T-R-I-R-N-A-L-K-A-E-H-L-Y-V-D-L-E-H-S-K-M-R-E-A-I-V-R-I-L-K-Q-H-G-F-L-A-H-Y-L-V-K-E-E-N-R-K-R-T-M-R-I-F-L-Q-Y-S-N-D-R-R-P-V-I-R-Q-L-K-R-V-S-K-P-S-R-R-V-Y-V-P-A-A-K-I-P-Y-V-F-G-N-M-G-I-S-V-L-S-T-S-Q-G-V-L-D-G-A-T-A-R-A-K-N-I-G-G-E-L-L-C-L-V-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-R-L-K-K-L-Y-T-E-E-I-R-K-S-L-Q-E-K-F-G-Y-G-N-T-M-Q-I-P-V-L-R-K-I-V-I-S-M-G-L-A-E-A-A-K-D-K-N-L-F-Q-A-H-L-E-E-L-S-M-I-S-G-Q-K-P-L-V-T-K-A-R-N-S-I-A-G-F-K-L-R-E-G-Q-G-I-G-A-K-V-T-L-R-G-Q-R-M-Y-D-F-M-D-R-F-C-N-I-V-S-P-R-I-R-D-F-R-G-F-S-M-K-G-D-G-R-G-C-Y-S-L-G-L-D-D-Q-Q-I-F-P-E-I-D-L-D-R-V-K-R-T-Q-G-M-N-I-T-W-V-T-T-A-Q-T-D-V-E-C-T-T-L-L-E-L-M-G-L-R-F-K-K-A-Q"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-R-Y-S-V-C-V-G-D-T-V-Y-V-L-A-G-N-D-K-G-K-Q-G-K-V-L-S-C-L-R-E-K-N-K-V-V-V-E-G-V-N-V-R-T-K-N-I-K-R-S-Q-E-N-P-K-G-K-R-I-S-I-E-A-P-I-H-V-S-N-V-R-L-S-I-D-G-A-P-A-K-L-S-V-K-V-T-E-N-G-R-E-L-W-N-K-S-P-D-G-T-S-K-L-Y-R-S-V-K-E-R-K-G"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-Q-L-K-V-A-D-N-T-G-A-K-K-V-K-C-F-K-V-L-G-G-S-R-R-R-Y-A-T-V-G-D-I-I-V-C-S-V-R-D-V-E-P-D-S-S-I-K-K-G-D-V-V-K-A-V-I-V-R-T-R-R-D-I-L-R-K-D-G-S-S-L-R-F-D-T-N-S-C-V-I-I-D-E-K-G-N-P-K-G-T-R-I-F-G-P-I-A-R-E-I-R-D-R-G-F-V-K-I-S-S-L-A-P-E-V-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-S-E-E-R-G-L-R-K-T-K-V-G-V-V-V-S-S-K-M-D-K-T-V-V-V-R-V-E-R-I-Y-S-H-P-Q-Y-A-K-V-V-R-D-S-K-K-Y-Y-A-H-N-G-L-D-V-S-E-G-D-K-V-K-I-Q-E-T-R-P-I-S-K-L-K-R-W-R-V-V-E-R-V-S"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-F-R-K-Q-Q-K-G-Q-F-A-G-L-S-K-G-A-T-F-V-D-F-G-E-F-G-M-Q-T-L-E-R-G-W-V-T-S-R-Q-I-E-A-C-R-V-A-I-N-R-Y-L-K-R-K-G-K-V-W-I-R-V-F-P-D-K-S-V-T-K-K-P-A-E-T-R-M-G-K-G-K-G-A-P-D-H-W-V-A-V-V-R-P-G-R-I-L-F-E-V-A-N-V-S-R-E-D-A-Q-D-A-L-R-R-A-A-A-K-L-G-I-R-T-R-F-V-K-R-V-E-R-V"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-F-K-A-T-A-R-Y-I-R-V-Q-P-R-K-A-R-L-A-A-G-L-M-R-N-L-S-V-M-E-A-Q-Q-Q-L-N-F-S-Q-L-K-A-G-R-C-L-K-K-V-L-D-S-A-V-A-N-A-V-L-N-E-N-V-K-R-E-Q-L-S-V-I-E-V-R-V-D-A-G-P-V-Y-K-R-A-K-S-K-S-R-G-G-R-S-P-I-L-K-R-T-S-H-L-T-V-I-V-G-E-K-E-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-L-R-K-G-P-F-V-D-H-H-L-I-K-K-V-R-A-M-N-L-L-E-K-K-S-P-I-K-T-W-S-R-R-S-M-I-T-P-E-M-I-G-H-T-F-E-V-H-N-G-K-K-F-L-T-V-F-V-S-E-T-M-V-G-H-K-L-G-E-F-S-P-T-R-I-F-K-S-H-P-V-K-K-G"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-K-D-P-Y-D-V-I-K-R-H-Y-V-T-E-K-A-K-T-L-E-G-L-S-L-G-N-G-E-G-K-K-K-G-S-F-C-K-H-P-K-Y-T-F-V-V-S-C-D-A-T-K-P-L-I-A-Q-A-L-E-S-I-Y-A-D-K-K-V-K-V-K-S-V-N-T-I-C-V-K-P-Q-P-A-R-M-F-R-G-K-R-K-G-K-T-A-G-F-K-K-A-V-V-T-F-Y-E-G-H-S-I-G"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-S-L-T-D-T-E-K-K-M-A-A-A-L-E-F-F-H-K-E-V-R-S-F-R-T-G-K-A-N-P-A-L-V-E-T-V-T-V-D-V-Y-G-T-T-M-R-L-S-D-L-A-S-I-S-V-A-D-T-R-Q-L-V-I-S-P-Y-D-A-N-N-V-S-A-I-S-K-G-I-I-A-A-N-L-N-L-Q-P-D-V-E-G-T-I-V-R-I-K-V-P-E-P-T-A-E-Y-R-N-E-V-I-K-Q-L-R-R-K-S-E-E-A-K-V-A-I-R-N-I-R-R-E-S-N-D-K-L-K-K-D-S-D-L-T-E-D-A-V-K-G-M-E-K-K-V-Q-E-L-T-D-K-F-C-K-Q-I-D-E-I-T-K-Q-K-E-A-E-L-S-S-I"} +{"text": "### FUNCTION A probable RNA-binding protein ### SEQUENCE -M-K-D-F-L-A-Y-I-I-K-N-L-V-D-R-P-E-E-V-H-I-K-E-V-Q-G-T-H-T-I-I-Y-E-L-T-V-A-K-P-D-I-G-K-I-I-G-K-E-G-R-T-I-K-A-I-R-T-L-L-V-S-V-A-S-R-N-N-V-K-V-S-L-E-I-M-E-D-K"} +{"text": "### FUNCTION Strong inhibitor of bacterial serine proteases such as subtilisin ### SEQUENCE -M-P-N-T-A-R-W-A-V-T-L-T-L-T-A-T-A-V-C-G-P-L-A-G-A-S-L-A-T-P-N-A-A-A-S-G-L-Y-A-P-S-A-L-V-L-T-T-G-H-G-Q-S-A-A-T-A-T-P-E-R-A-V-T-L-N-C-A-P-T-A-S-G-T-H-P-A-A-V-S-A-C-A-E-L-R-A-T-G-G-D-F-D-A-L-S-A-R-S-D-A-M-C-T-R-Q-Y-D-P-V-V-V-T-V-E-G-V-W-Q-G-K-R-V-A-Y-E-R-T-F-A-N-E-C-V-K-N-S-Y-G-T-T-V-F-T-F"} +{"text": "### FUNCTION Plays a role in the release of virion progenies by disrupting the host plasma membrane ### SEQUENCE -M-L-S-L-M-V-S-R-D-Q-T-N-D-R-S-D-D-K-P-A-R-S-N-P-T-D-C-S-V-H-T-E-P-S-D-A-N-N-R-T-G-V-H-S-G-R-H-P-R-E-A-H-S-Q-V-R-D-L-D-L-Q-F-D-C-G-G-H-R-V-R-A-N-C-L-F-P-W-L-P-W-L-N-C-G-C-S-L-H-T-A-E-Q-W-E-L-Q-V-R-S-D-A-P-D-C-P-E-P-T-G-Q-L-Q-L-L-Q-A-S-E-S-E-S-H-S-E-V-K-H-T-P-W-W-R-L-C-T-K-W-H-H-K-R-R-D-L-P-R-K-P-E"} +{"text": "### FUNCTION The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane ### SEQUENCE -M-S-I-F-K-R-A-K-K-T-V-L-I-P-P-P-H-L-L-S-G-D-E-E-R-V-T-I-L-S-A-E-G-E-I-K-V-T-G-R-R-P-T-T-L-E-E-K-I-Y-Y-S-M-N-L-A-A-A-I-V-G-G-D-L-H-P-S-F-K-S-M-T-Y-L-F-Q-K-E-M-E-F-G-S-T-Q-E-K-V-N-F-G-S-R-K-P-A-P-Q-T-T-Y-Q-V-T-K-A-R-E-V-Y-L-Q-T-Q-P-L-E-K-K-I-P-M-Q-T-Y-S-V-S-T-E-G-A-T-I-T-F-T-G-R-F-L-F-S-S-S-H-V-G-C-D-D-N-R-T-K-L-A-G-L-D-G-F-T-T-S-N-S-Y-Q-R-V-K-D-Y-Y-A-Q-E-T-A-L-A-L-T-F-A-A-P-E-K-R-G-K-E-K"} +{"text": "### FUNCTION Plays an essential role for the viral pathogenicity ### SEQUENCE -M-D-H-R-D-I-N-T-N-M-E-A-L-R-E-A-L-R-Y-K-N-E-V-A-G-H-G-F-S-F-D-D-G-D-L-V-W-R-E-E-D-D-A-T-W-R-R-L-C-D-V-V-N-A-L-I-S-S-K-R-M-Q-R-V-L-Y-M-D-L-S-I-T-K-G-E-G-H-L-L-L-V-D-L-Q-G-T-K-N-R-L-Y-K-E-P-R-F-R-R-H-L-I-L-I-E-D-F-L-A-Y-P-R"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-R-H-G-S-I-P-G-T-R-G-H-V-R-P-L-A-L-L-G-D-P-V-L-H-A-P-C-E-E-V-T-D-H-G-P-E-L-A-R-L-V-E-D-M-F-A-T-M-Y-A-A-N-G-V-G-L-A-A-N-Q-I-G-V-P-L-R-V-F-V-Y-D-C-P-D-D-E-D-V-R-H-V-G-H-V-V-N-P-R-L-I-E-A-D-G-V-V-L-R-G-P-E-G-C-L-S-L-P-G-L-E-A-G-T-E-R-Y-D-R-A-V-V-E-G-F-T-T-D-G-E-P-V-R-V-L-G-T-G-W-F-A-R-C-L-Q-H-E-C-D-H-L-D-G-G-V-Y-V-D-R-V-S-G-W-R-H-R-R-V-M-R-Q-A-A-R-A-P-W-N-R-Q-R-A-P-E-P-R"} +{"text": "### FUNCTION Plays an essential role for the viral pathogenicity ### SEQUENCE -M-D-H-R-D-T-N-T-N-M-E-A-L-R-E-V-L-R-Y-K-N-E-V-A-G-H-G-F-L-F-D-D-G-D-L-V-W-R-E-E-D-D-A-T-W-R-R-L-Y-D-V-V-N-A-L-I-S-S-K-R-M-Q-R-V-L-Y-M-D-L-S-I-T-K-G-E-G-H-L-L-F-V-D-L-Q-G-T-K-N-R-L-Y-K-E-P-R-F-R-R-H-L-I-L-I-E-D-F-L-A-Y-P-R"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-S-G-K-G-A-P-E-L-S-V-R-N-C-G-D-L-R-V-A-V-I-A-A-Q-W-H-E-K-V-M-D-G-L-V-D-G-A-L-R-A-L-H-E-L-G-I-D-E-P-T-L-L-R-V-P-G-S-F-E-L-P-V-V-A-K-V-L-A-G-R-G-Y-D-A-I-V-A-L-G-V-V-I-R-G-G-T-P-H-F-D-F-V-C-Q-G-V-T-Q-G-L-T-Q-V-S-V-D-T-G-V-P-V-G-F-G-V-L-T-C-D-T-E-E-Q-A-L-D-R-A-G-I-E-G-S-H-E-D-K-G-H-E-A-V-T-A-A-V-A-T-A-A-T-L-R-S-V-S-E-P-W-R"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-S-S-S-I-T-A-P-E-G-I-I-N-P-P-I-D-E-L-L-E-A-T-D-S-K-Y-S-L-V-I-Y-A-A-K-R-A-R-Q-I-N-A-Y-Y-S-Q-L-G-E-G-L-L-E-Y-V-G-P-L-V-D-T-H-V-H-E-K-P-L-S-I-A-L-R-E-I-N-A-G-L-L-T-S-E-P-V-E-G-P-A-Q"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-A-A-R-N-T-A-R-K-R-A-F-Q-I-L-F-E-G-D-Q-R-G-V-D-V-L-T-V-L-A-D-W-I-R-H-S-R-T-D-T-R-Q-P-P-V-S-E-Y-T-M-Q-L-V-E-G-Y-A-K-K-V-N-R-I-D-E-L-I-S-Q-Y-A-V-G-W-T-L-D-R-M-P-V-V-D-R-N-I-L-R-L-G-T-Y-E-L-L-W-V-D-E-T-P-D-A-V-V-L-D-E-A-V-Q-L-A-K-E-F-S-T-D-D-S-P-A-F-V-N-G-L-L-G-R-L-K-E-L-K-P-S-L-R-R-E-E-A"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-T-N-D-L-K-N-G-L-V-L-K-L-D-G-G-Q-L-W-S-V-V-E-F-Q-H-V-K-P-G-K-G-P-A-F-V-R-T-K-L-K-N-V-L-S-G-K-V-V-D-K-T-F-N-A-G-V-K-V-E-T-A-T-I-D-K-R-D-M-Q-F-S-Y-M-D-G-E-Y-F-V-F-M-D-M-D-T-Y-D-Q-L-M-V-D-R-K-S-V-G-D-A-A-N-F-L-I-E-G-F-T-A-T-V-A-Q-H-E-G-E-V-L-F-V-E-L-P-A-A-V-E-L-V-I-Q-E-T-E-P-G-V-Q-G-D-R-S-T-G-G-T-K-P-A-T-L-E-T-G-H-Q-I-Q-V-P-L-F-I-T-T-G-E-K-I-K-V-D-T-R-T-S-D-Y-L-G-R-V-N-S"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-G-M-R-R-G-R-R-L-A-V-D-V-G-D-A-R-I-G-V-A-S-C-D-P-D-G-I-L-A-T-P-V-E-T-V-P-G-R-D-V-P-A-A-H-R-R-L-K-Q-L-V-E-E-Y-E-P-I-E-V-V-L-G-L-P-R-S-L-K-G-G-E-G-P-A-A-V-K-V-R-A-F-A-Q-E-L-A-R-V-I-A-P-V-P-V-R-L-M-D-E-R-M-T-T-V-T-A-S-Q-G-L-R-A-S-G-V-K-S-K-K-G-R-S-V-I-D-Q-A-A-A-V-I-I-L-Q-Q-A-L-E-S-E-R-V-S-G-K-A-P-G-E-G-V-E-V-V-I"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-E-L-V-N-I-T-E-L-L-L-S-R-I-R-D-V-R-D-Y-P-E-P-G-V-V-F-K-D-I-T-P-L-L-A-D-P-A-A-F-T-A-L-T-G-A-L-A-E-L-T-V-R-H-G-A-T-K-I-V-G-L-E-A-R-G-F-I-L-G-A-P-A-A-V-Q-A-G-V-G-F-I-P-V-R-K-A-G-K-L-P-G-A-T-L-S-Q-S-Y-D-L-E-Y-G-S-A-E-I-E-V-H-A-E-D-L-V-A-G-D-R-V-M-V-V-D-D-V-L-A-T-G-G-T-A-E-A-S-L-Q-L-I-R-R-A-G-A-E-V-A-G-V-S-V-L-M-E-L-G-F-L-G-G-R-A-R-L-E-P-A-L-A-G-A-P-L-E-A-L-L-Q-I"} +{"text": "### FUNCTION Determines virus infectivity ### SEQUENCE -M-E-R-T-I-Q-S-P-M-G-R-R-R-G-S-S-G-R-R-K-R-N-A-N-I-I-S-P-P-A-Y-A-I-Y-P-A-P-Q-Y-R-Y-P-R-W-E-F-V-M-N-D-L-Y-S-Q-T-A-R-L-Q-K-E-E-I-I-I-T-Y-R-Y-A-V-W-A-R-E-W-K-I-Q-T-G-F-L-D-L-G-Y-L-M-T-P-A-G-T-H-T-T-G-E-L-N-E-L-D-L-F-W-V-R-Y-T-L-C-Q-H-R-S-P-K-W-R-E-L-L-L-G-E-M-T-H-T-S-C-R-R-T-A-Q-A-A-V-V-S-H-T-K-P-H-T-L-Q-R-L-A-G-L-T-L-V-C-N-Q-N-L-C-W-Y-P-V-G-T-V-T-R-N-S-P-L-W-M-H-F-T-T-G-K-E-P-T-I-Q-Q-L-S-G-H-P"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-S-Q-A-Q-E-N-E-H-A-G-P-A-V-P-Q-T-R-T-A-R-H-R-R-I-V-D-I-L-N-R-Q-P-V-R-S-Q-S-Q-L-A-K-L-L-A-D-D-G-L-S-V-T-Q-A-T-L-S-R-D-L-D-E-L-N-A-V-K-I-R-N-N-D-G-D-L-I-Y-A-V-P-S-E-G-G-F-R-T-P-R-V-P-L-G-E-S-A-K-E-E-R-M-R-R-L-S-A-E-L-L-I-S-A-E-A-S-A-N-L-V-V-L-R-T-P-P-G-A-A-Q-F-L-A-S-A-I-D-Q-A-E-L-H-D-I-L-G-T-I-A-G-D-D-T-L-L-L-I-S-R-E-P-T-G-G-Q-A-L-A-D-H-L-L-R-L-A-Q-N-H-H"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-A-V-N-A-H-K-K-R-R-A-I-L-E-A-A-S-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-V-T-H-S-L-V-Y-N-Y-N-D-R-K-K-R-K-G-D-F-R-Q-L-W-I-Q-R-I-N-A-A-A-R-A-N-G-M-T-Y-N-R-L-I-Q-G-L-K-A-A-N-I-E-V-D-R-K-I-L-A-E-L-A-V-N-D-A-G-A-F-A-A-L-V-E-V-A-Q-K-A-L-P-S-D-V-N-A-P-K-A-A"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-F-G-R-L-G-A-P-E-I-I-L-I-L-V-V-I-I-L-L-F-G-A-K-K-L-P-D-M-A-R-S-L-G-K-S-A-R-I-L-K-S-E-A-K-A-M-K-S-E-G-Q-E-S-T-P-A-G-P-P-N-T-D-E-Q-P-P-A-Q-R-T-I-Q-A-A-P-G-D-V-T-S-S-R-P-V-S-E-P-T-D-T-T-K-R"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-G-S-V-R-K-A-S-A-W-L-G-L-V-D-D-N-D-D-E-R-Y-Y-D-D-D-Y-A-E-G-Q-E-S-G-E-A-W-V-T-D-P-R-V-K-V-A-S-E-T-A-E-E-K-G-R-R-I-G-T-V-T-P-D-S-F-R-D-A-R-G-I-G-E-L-F-R-D-G-V-P-V-I-I-N-L-T-A-M-E-P-T-D-A-K-R-V-V-D-F-A-A-G-L-T-F-G-L-R-G-T-I-E-R-V-A-T-R-V-F-L-L-T-P-A-N-T-E-I-V-S-G-E-A-A-G-R-P-T-D-G-F-F-N-Q-S"} +{"text": "### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate with acetyl coenzyme A ### SEQUENCE -M-T-A-A-H-A-D-L-Q-A-E-F-L-E-M-P-E-G-L-R-I-D-R-P-D-V-A-D-G-S-A-L-W-R-I-A-K-D-S-K-T-L-D-L-N-S-S-Y-S-Y-L-L-W-C-R-D-F-A-G-T-T-A-V-A-R-A-A-D-G-T-P-V-G-F-I-T-A-Y-V-R-P-E-R-P-H-T-L-L-V-W-Q-V-A-V-D-A-A-Y-R-G-R-G-L-A-A-R-M-L-D-G-L-T-A-R-V-T-D-E-Y-G-V-T-G-I-E-T-T-I-S-P-G-N-T-A-S-E-R-L-F-T-S-Y-A-Q-R-H-G-A-D-L-E-R-E-V-L-F-E-A-G-L-F-P-D-A-P-H-D-P-E-V-L-Y-R-I-G-P-L-S-H"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-R-S-F-K-D-I-E-G-T-D-R-H-V-K-A-A-S-G-T-W-E-S-K-R-I-V-L-A-K-E-K-V-G-F-S-L-H-E-T-V-L-Y-A-G-T-E-T-S-M-W-Y-A-N-H-I-E-A-V-L-C-V-E-G-E-A-E-L-T-D-D-E-T-G-E-K-H-W-I-T-P-G-T-M-Y-L-L-D-G-H-E-R-H-T-M-R-P-K-T-D-F-R-C-V-C-V-F-N-P-P-V-T-G-R-E-D-H-D-E-N-G-V-Y-P-L-L-T-E-P-E-E-V"} +{"text": "### FUNCTION Part of cytochrome c oxidase, its function is unknown ### SEQUENCE -M-K-I-Q-G-K-M-F-I-W-L-A-V-F-I-L-A-M-A-I-I-Y-G-V-W-S-K-E-P-A-G-T-T-A-L-F-L-A-F-G-L-S-I-M-I-G-Y-Y-L-A-F-T-A-R-R-V-D-A-G-A-Q-D-N-K-E-A-D-V-A-D-D-A-G-E-V-G-F-F-S-P-H-S-W-Q-P-L-A-L-G-I-G-G-A-L-A-F-M-G-V-V-F-G-W-W-L-L-Y-F-S-A-P-I-I-L-I-G-L-W-G-W-V-F-E-Y-Y-R-G-E-S-R-T-Q"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-I-D-V-N-N-E-S-G-T-E-V-D-E-Q-A-I-L-D-I-A-R-Y-A-L-A-R-M-R-I-H-P-L-S-E-L-S-V-I-V-V-D-A-D-A-M-E-Q-L-H-I-Q-W-M-D-L-P-G-P-T-D-V-M-S-F-P-M-D-E-L-R-P-P-M-K-D-D-D-E-P-P-Q-G-L-L-G-D-I-V-L-C-P-E-V-A-E-R-Q-G-K-E-A-P-T-Q-H-S-M-D-E-E-L-Q-L-L-A-V-H-G-V-L-H-L-L-G-Y-D-H-E-E-P-D-E-K-A-E-M-F-G-L-Q-A-A-I-V-D-G-W-R-A-E-K-G-L-T-G-P-S-P-A-P-T-V-S"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-I-K-R-N-K-T-N-E-K-A-R-L-R-N-K-A-V-K-S-S-L-K-T-A-I-R-K-A-R-E-A-A-A-A-G-D-V-E-K-A-T-E-Y-Q-R-A-A-A-R-Q-L-D-K-A-V-S-K-G-V-I-H-K-N-Q-A-A-N-K-K-S-A-L-A-S-K-V-A-P-L-K-G"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-R-S-G-G-R-Q-H-K-V-A-V-G-D-I-V-E-V-D-K-I-S-T-A-Q-V-G-D-T-V-E-L-S-T-L-L-V-V-D-G-D-A-V-T-S-D-P-W-V-L-A-G-I-K-V-Q-A-E-V-V-D-H-H-K-G-A-K-I-D-I-L-R-Y-K-N-K-T-G-Y-R-R-R-Q-G-H-R-Q-Q-Y-T-A-I-K-V-T-E-I-P-T-A-A-K"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-N-D-R-M-V-W-I-D-C-E-M-T-G-L-S-L-S-D-D-A-L-I-E-V-A-A-L-V-T-D-S-E-L-N-V-L-G-E-G-V-D-I-V-I-R-P-P-D-A-A-L-E-T-M-P-E-V-V-R-T-M-H-T-A-S-G-L-L-D-E-L-A-A-G-T-T-L-A-D-A-E-A-Q-V-L-A-Y-V-R-E-H-V-K-E-P-G-K-A-P-L-C-G-N-S-V-G-T-D-R-G-F-L-A-R-D-M-S-A-L-E-T-Y-L-H-Y-R-I-V-D-V-S-S-V-K-E-L-A-R-R-W-Y-P-R-A-Y-F-N-S-P-E-K-S-G-N-H-R-A-L-A-D-I-R-E-S-I-A-E-L-R-Y-Y-R-E-A-I-F-V-P-Q-P-G-P-D-S-E-T-A-R-T-I-A-A-K-H-V-L-P-A-Q"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-G-R-V-T-A-P-A-P-L-E-I-E-K-T-E-S-A-E-E-V-F-A-V-P-E-P-D-V-P-W-V-T-I-V-H-N-D-P-V-N-L-M-S-Y-V-T-Y-V-F-Q-T-Y-F-G-Y-S-K-D-K-A-T-K-L-M-L-D-V-H-H-K-G-R-A-V-V-S-S-G-T-R-E-E-M-E-R-D-V-Q-A-M-H-G-Y-G-L-W-A-T-L-Q-Q-D-R-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-Y-V-P-K-E-S-Q-P-K-Q-G-G-G-A-S-G-K-V-K-D-G-K-R-K-I-V-A-Q-N-K-K-A-R-H-D-Y-A-I-I-D-T-Y-E-A-G-L-V-L-T-G-T-E-V-K-S-L-R-Q-G-R-A-S-L-T-D-G-F-V-Q-I-D-G-N-E-A-W-L-H-N-A-H-I-P-E-Y-S-Q-G-T-W-T-N-H-T-V-R-R-K-R-K-L-L-L-H-R-E-E-I-D-K-L-A-S-K-S-E-E-T-G-H-T-I-V-P-L-A-L-Y-F-K-D-G-R-A-K-A-E-I-A-L-A-R-G-K-K-E-Y-D-K-R-Q-T-L-R-E-K-Q-D-R-R-E-S-D-R-A-I-A-A-A-K-R-K-Q-R-G-E"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-S-I-I-G-V-G-I-D-V-A-E-I-D-R-F-R-A-S-L-E-R-T-P-G-L-A-D-R-L-F-L-E-R-E-L-L-L-P-N-G-E-R-R-G-I-A-S-L-A-A-R-F-A-A-K-E-A-V-A-K-A-L-G-A-P-G-G-L-Y-W-T-D-A-E-V-W-V-E-D-S-G-R-P-R-L-R-V-T-G-T-V-A-A-R-A-A-E-L-G-V-Q-S-W-H-V-S-L-S-H-D-A-G-V-A-S-A-V-V-V-A-E-G"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-Y-S-P-K-P-G-D-I-T-R-Q-W-Y-V-I-D-A-Q-D-V-V-L-G-R-L-A-T-T-A-A-N-I-L-R-G-K-H-K-P-I-Y-A-P-H-V-D-A-G-D-F-V-I-I-I-N-A-D-K-V-H-L-S-G-N-K-K-T-Q-K-L-A-Y-R-H-S-G-Y-P-G-G-L-R-S-V-R-Y-D-E-L-L-A-K-N-P-E-K-A-V-E-K-A-I-K-G-M-I-P-K-N-T-L-G-R-Q-V-L-S-K-L-K-V-Y-S-G-D-Q-H-P-H-A-A-Q-Q-P-V-P-F-E-I-T-Q-V-A-Q"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-P-P-K-G-R-Q-G-A-A-K-K-V-R-R-K-E-K-K-N-V-A-H-G-H-A-H-I-K-S-T-F-N-N-T-I-V-S-I-T-D-P-S-G-N-V-I-S-W-A-S-A-G-H-V-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-S-A-A-R-R-A-Q-E-H-G-M-R-K-V-D-V-F-V-K-G-P-G-S-G-R-E-T-A-I-R-S-L-Q-A-T-G-L-E-V-G-S-I-Q-D-V-T-P-T-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-E-N-N-P-L-K-I-H-N-L-R-P-A-P-G-A-K-T-A-K-T-R-V-G-R-G-E-A-S-K-G-K-T-A-G-R-G-T-K-G-T-K-A-R-Y-Q-V-P-E-R-F-E-G-G-Q-M-P-L-H-M-R-L-P-K-L-K-G-F-K-N-P-F-R-T-E-Y-Q-V-V-N-L-D-K-L-T-A-L-Y-P-E-G-G-E-V-T-V-E-G-L-V-A-K-G-A-V-R-K-N-S-L-V-K-V-L-G-Q-G-E-I-S-V-A-L-Q-V-T-V-D-A-V-S-G-S-A-K-E-K-I-T-A-A-G-G-T-V-T-E-L-V"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-Y-G-V-K-I-A-K-G-D-A-Y-K-R-A-A-I-K-R-R-H-I-R-I-R-K-H-I-S-G-T-A-E-R-P-R-L-V-V-T-R-S-N-R-H-I-V-A-Q-V-I-D-D-V-K-G-H-T-L-A-S-A-S-T-L-D-T-T-I-R-G-G-E-S-D-K-S-A-Q-A-K-S-V-G-A-L-V-A-E-R-A-K-A-A-G-V-E-A-V-V-F-D-R-G-G-N-Q-Y-A-G-R-I-A-A-L-A-D-A-A-R-E-A-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-L-P-I-T-V-P-A-G-V-D-V-T-I-D-G-R-T-V-Q-V-K-G-P-K-G-S-L-S-H-T-I-A-A-P-I-E-I-A-K-G-E-D-G-V-L-N-V-T-R-P-N-D-E-R-Q-N-K-A-L-H-G-L-S-R-T-L-V-A-N-M-I-T-G-V-T-Q-G-Y-V-K-K-L-E-I-S-G-V-G-Y-R-V-L-A-K-G-S-N-L-E-F-S-L-G-Y-S-H-S-I-T-V-E-A-P-E-G-I-T-F-K-V-E-A-P-T-R-F-S-V-E-G-I-D-K-Q-K-V-G-E-V-A-A-N-I-R-K-L-R-K-P-D-P-Y-K-A-K-G-V-K-Y-E-G-E-V-I-R-R-K-V-G-K-A-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-I-A-D-M-L-T-R-L-R-N-A-N-S-A-Y-H-D-T-V-G-M-P-H-S-K-I-K-S-H-I-A-E-I-L-Q-Q-E-G-F-I-T-G-W-K-V-E-D-A-E-V-G-K-N-L-V-L-E-L-K-F-G-P-N-R-E-R-S-I-A-G-I-K-R-I-S-K-P-G-L-R-V-Y-A-K-S-T-N-L-P-K-V-L-G-G-L-G-V-A-I-I-S-T-S-H-G-L-L-T-D-K-Q-A-G-K-K-G-V-G-G-E-V-L-A-Y-V-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-T-T-T-T-P-R-L-K-T-K-Y-R-E-E-I-A-G-K-L-Q-E-E-F-S-Y-E-N-V-M-Q-T-P-G-L-V-K-I-V-V-N-M-G-V-G-D-A-A-R-D-S-K-L-I-D-G-A-I-R-D-L-T-T-I-T-G-Q-K-P-A-V-T-K-A-R-K-S-I-A-Q-F-K-L-R-E-G-Q-P-I-G-A-H-V-T-L-R-G-D-R-M-W-E-F-L-D-R-T-L-S-L-A-L-P-R-I-R-D-F-R-G-L-S-P-K-Q-F-D-G-R-G-N-Y-T-F-G-L-T-E-Q-V-M-F-H-E-I-D-Q-D-K-I-D-R-V-R-G-M-D-I-T-V-V-T-T-A-T-N-D-A-E-G-R-A-L-L-R-H-L-G-F-P-F-K-E-A"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-I-K-K-G-D-T-V-Q-V-I-T-G-K-D-K-G-K-Q-G-K-V-I-A-A-Y-P-R-D-E-R-V-L-V-E-G-V-N-R-V-K-K-H-T-K-A-G-P-T-A-G-G-S-Q-A-G-G-I-V-T-T-E-A-P-I-H-V-S-N-V-Q-L-V-V-E-K-D-G-N-K-V-V-T-R-V-G-Y-R-F-D-D-E-G-N-K-I-R-V-A-K-R-T-G-E-D-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-R-V-A-D-N-T-G-A-K-E-I-L-C-I-R-V-L-G-G-S-G-R-R-Y-A-G-I-G-D-V-I-V-A-T-V-K-D-A-I-P-G-G-N-V-K-K-G-D-V-V-K-A-V-I-V-R-T-V-K-E-R-R-R-P-D-G-S-Y-I-R-F-D-E-N-A-A-V-I-L-K-N-D-G-D-P-R-G-T-R-I-F-G-P-V-G-R-E-L-R-E-K-K-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-S-N-V-T-E-T-N-E-Q-R-G-F-R-K-T-R-E-G-L-V-V-S-D-K-M-D-K-T-V-V-V-A-V-E-D-R-V-K-H-A-L-Y-G-K-V-I-R-R-T-N-K-L-K-A-H-D-E-Q-N-A-A-G-V-G-D-R-V-L-L-M-E-T-R-P-L-S-A-T-K-R-W-R-V-V-E-I-L-E-K-A-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-I-P-R-R-V-K-H-R-K-Q-H-H-P-K-R-R-G-Q-A-K-G-G-T-Q-V-S-F-G-E-Y-G-I-Q-A-L-T-P-A-Y-V-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-H-I-K-R-G-G-K-V-W-I-N-I-Y-P-D-R-P-L-T-K-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-W-W-I-A-N-V-H-P-G-R-V-M-F-E-L-S-Y-P-N-E-K-I-A-R-E-A-L-T-R-A-A-H-K-L-P-M-K-C-R-I-V-K-R-E-A-G-E-A"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-R-A-Q-A-R-Y-I-R-V-T-P-M-K-A-R-R-V-V-D-L-I-R-G-M-D-A-T-E-A-Q-A-V-L-R-F-A-P-Q-A-A-S-V-P-V-G-K-V-L-D-S-A-I-A-N-A-A-H-N-Y-D-H-T-D-A-D-S-L-F-I-S-E-A-Y-V-D-E-G-P-T-L-K-R-F-R-P-R-A-Q-G-R-A-Y-R-I-R-K-R-T-S-H-I-T-V-V-V-S-S-K-E-G-T-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-V-D-D-H-L-I-K-K-V-D-A-Q-N-E-A-G-S-K-N-V-I-K-T-W-S-R-R-S-M-I-I-P-A-M-L-G-H-T-I-A-V-H-N-G-K-T-H-I-P-V-F-V-T-E-S-M-V-G-H-K-L-G-E-F-S-P-T-R-T-F-R-G-H-V-K-D-D-R-K-S-K-R-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-A-P-K-R-P-V-I-I-D-P-V-Y-G-S-P-L-V-T-S-L-I-N-K-V-L-L-N-G-K-R-S-T-A-E-R-I-V-Y-G-A-M-E-G-L-R-E-K-T-G-N-D-P-I-I-T-L-K-R-A-L-E-N-I-K-P-T-L-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-I-E-V-K-P-G-R-A-N-T-L-A-L-R-W-L-V-G-Y-S-R-A-R-R-E-K-T-M-T-E-R-L-L-N-E-L-L-D-A-S-N-G-L-G-A-A-V-K-K-R-E-D-T-H-K-M-A-E-S-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-T-K-L-S-Q-E-E-L-L-E-Q-F-E-S-L-T-L-I-E-L-A-E-F-V-K-A-F-E-E-K-F-D-V-T-A-A-A-A-V-A-A-A-P-A-G-P-V-A-A-A-E-A-A-E-E-Q-D-E-F-D-V-I-L-T-G-A-G-D-K-K-I-Q-V-I-K-V-V-R-E-L-T-S-L-G-L-K-E-A-K-D-L-V-D-G-A-P-K-P-V-L-E-K-V-A-K-E-A-A-E-K-A-A-E-S-L-K-G-A-G-A-S-V-E-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-R-P-D-K-A-A-A-V-A-E-L-A-D-Q-F-R-S-S-N-A-A-V-L-T-E-Y-R-G-L-T-V-A-Q-L-K-T-L-R-R-S-L-G-E-D-A-Q-Y-A-V-V-K-N-T-L-T-K-I-A-A-N-E-A-G-I-N-T-L-D-D-L-F-N-G-P-T-A-V-A-F-I-T-G-D-P-V-V-S-A-K-G-L-R-D-F-A-K-D-N-P-N-L-V-I-K-G-G-V-L-D-G-K-A-L-S-A-D-E-I-K-K-L-A-D-L-E-S-R-E-V-L-L-A-K-L-A-G-A-F-K-G-K-Q-S-Q-A-A-S-L-F-Q-A-L-P-S-K-F-V-R-T-A-E-A-L-R-A-K-K-A-E-Q-G-G-A-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-P-P-K-K-K-K-V-T-G-L-I-K-L-Q-I-Q-A-G-A-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-Y-N-A-A-T-E-S-Q-R-G-W-V-I-P-V-E-I-T-V-Y-E-D-R-S-F-T-F-I-T-K-T-P-P-A-A-K-M-I-L-K-A-A-G-V-E-K-G-S-G-E-P-H-K-T-K-V-A-K-I-T-Q-A-Q-V-R-E-I-A-T-T-K-L-P-D-L-N-A-N-D-L-D-A-A-S-K-I-I-A-G-T-A-R-S-M-G-I-T-V-E-G"} +{"text": "### FUNCTION Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released This sigma factor is required for normal cell wall integrity ### SEQUENCE -M-A-H-G-E-V-L-E-F-E-E-Y-V-R-T-R-Q-D-A-L-L-R-S-A-R-R-L-V-P-D-P-V-D-A-Q-D-L-L-Q-T-A-L-V-R-T-Y-G-R-W-D-G-I-A-D-K-R-L-A-D-A-Y-L-R-R-V-M-I-N-T-R-T-E-W-W-R-A-R-K-L-E-E-V-P-T-E-Q-L-P-D-A-S-V-D-D-S-T-E-Q-H-A-D-R-A-L-L-M-D-I-L-K-V-L-A-P-K-Q-R-S-V-V-V-L-R-H-W-E-Q-M-S-T-E-E-T-A-A-A-L-G-M-S-A-G-T-V-K-S-T-L-H-R-A-L-A-R-L-R-E-E-L-E-S-R-D-L-D-A-R-A-L-E-R-E-E-R-E-R-C-A-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-P-R-K-P-V-R-K-V-A-S-T-P-R-P-N-P-L-D-Q-N-G-I-T-Y-I-D-Y-K-D-T-D-L-L-R-K-F-L-S-D-R-G-K-I-R-S-R-R-V-T-R-V-T-A-Q-Q-Q-R-L-L-A-R-A-V-K-N-A-R-E-M-A-L-L-P-Y-S-S-R"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-N-D-R-R-Q-E-T-V-A-R-Y-A-T-R-R-A-E-L-T-E-I-I-R-R-P-S-T-P-E-A-E-R-R-A-A-Q-Q-E-L-R-R-Q-P-R-D-A-S-A-T-R-V-R-N-R-D-S-V-D-G-R-P-R-G-Y-H-R-A-F-G-L-S-R-V-N-L-R-E-Q-A-H-A-G-F-L-P-G-V-R-K-S-S-W"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Y-E-G-V-V-Q-D-L-I-D-E-L-G-R-L-P-G-V-G-P-K-S-A-Q-R-I-A-F-H-I-L-Q-A-E-P-T-D-V-R-R-L-A-Q-C-L-M-E-V-K-A-K-V-R-F-C-A-T-C-G-N-V-A-Q-E-E-L-C-N-I-C-R-D-P-R-R-D-L-S-V-I-C-V-V-E-E-P-K-D-V-V-A-I-E-R-T-R-E-F-R-G-K-Y-H-V-L-G-G-A-I-S-P-I-E-G-V-G-P-D-D-L-R-I-R-E-L-L-A-R-L-A-D-G-T-V-T-E-L-I-L-A-T-D-P-N-L-E-G-E-A-T-A-T-Y-L-A-R-M-I-K-P-M-G-L-K-V-T-R-L-A-S-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-G-R-A-F-E-G-R-R-L-L-D-V"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-I-P-G-G-G-Q-P-N-M-Q-Q-L-L-Q-Q-A-Q-K-M-Q-Q-D-L-A-N-A-Q-E-E-L-A-R-T-E-V-E-G-Q-A-G-G-G-L-V-K-A-T-V-T-G-S-G-E-L-R-A-L-V-I-D-P-K-A-V-D-P-E-D-T-E-T-L-A-D-L-V-V-A-A-V-Q-A-A-N-E-N-A-Q-A-L-Q-Q-Q-K-L-G-P-L-A-Q-G-L-G-G-G-G-I-P-G-L-P-F"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-D-D-V-R-G-A-L-L-Q-Q-I-K-D-K-A-V-V-H-G-K-V-T-L-S-S-G-L-E-A-D-Y-Y-V-D-L-R-R-I-T-L-D-G-E-A-A-P-L-V-G-Q-V-L-L-D-L-T-A-D-L-D-F-D-A-V-G-G-L-T-M-G-A-D-P-V-A-A-A-M-L-H-A-A-A-A-R-G-R-R-L-D-A-F-V-V-R-K-A-A-K-A-H-G-L-Q-R-R-V-E-G-P-E-I-K-G-R-R-V-L-V-V-E-D-T-S-T-T-G-G-S-P-L-T-A-V-E-A-V-R-E-A-G-A-E-V-V-G-V-A-T-I-V-D-R-A-T-G-A-A-E-K-I-E-A-G-A-G-V-P-Y-R-F-A-Y-D-K-D-E-L-G-L-D"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-L-P-T-E-N-R-L-R-R-R-E-D-F-A-T-A-V-R-R-G-R-R-A-G-R-P-L-L-V-V-H-L-R-S-G-A-T-D-P-H-A-P-G-E-S-A-P-P-T-R-A-G-F-V-V-S-K-A-V-G-G-A-V-V-R-N-K-V-K-R-R-L-R-H-L-M-R-D-R-V-A-L-L-P-P-G-S-L-V-V-V-R-A-L-P-G-A-G-D-A-D-H-A-Q-L-A-Q-D-L-D-A-A-L-Q-R-L-L-G-G-G-A-R"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-V-M-V-I-L-D-P-D-L-E-E-R-A-V-S-P-L-I-E-N-F-L-S-V-V-R-E-G-N-G-K-V-E-K-V-D-T-W-G-R-R-R-L-S-Y-E-I-K-K-K-P-E-G-I-Y-S-V-I-D-L-Q-A-E-P-A-V-V-K-E-L-D-R-Q-M-N-L-N-E-S-V-L-R-T-K-V-L-R-P-E-T-H"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-I-I-L-T-H-E-V-S-G-L-G-A-A-G-D-V-V-D-V-K-D-G-Y-A-R-N-Y-L-I-P-R-N-F-A-I-R-W-T-K-G-G-E-K-D-V-E-Q-I-R-R-A-R-K-I-H-E-I-Q-T-I-E-Q-A-N-E-I-K-A-R-L-E-G-V-K-V-R-L-A-V-R-S-G-D-A-G-R-L-F-G-S-V-T-P-A-D-V-A-S-A-I-K-A-S-G-G-P-E-V-D-K-R-R-I-E-L-G-S-P-I-K-T-L-G-A-H-E-T-S-V-R-L-H-P-E-V-A-A-K-V-N-I-E-V-V-A-A"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-S-E-V-K-L-A-A-E-P-R-T-E-F-G-K-G-A-A-R-R-I-R-R-E-S-K-V-P-A-V-V-Y-G-H-G-A-E-P-V-H-I-T-L-P-G-H-E-L-L-L-A-L-R-T-P-N-V-L-L-S-L-D-I-E-G-K-A-Q-L-A-I-P-K-A-V-Q-R-D-A-I-K-G-F-L-E-H-V-D-L-L-L-V-R-S-G-E-K-V-N-V-E-V-Y-V-H-T-E-G-D-L-A-P-G-A-Y-L-L-E-H-V-L-S-T-L-T-V-E-A-E-A-T-H-I-P-E-S-V-T-V-S-I-E-G-L-E-A-G-A-S-I-L-A-K-D-I-P-L-P-S-G-T-T-L-A-I-D-E-D-A-V-V-L-Q-V-L-A-A-Q-A-E-E-A-A-E-E-A-A-G-T-A-E-V-G-S-E-A"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-A-A-Q-T-Q-R-A-V-L-A-G-G-C-F-W-G-M-E-D-L-I-R-R-L-P-G-V-T-A-T-R-V-G-Y-T-G-G-D-V-P-N-A-T-Y-R-N-H-G-T-H-A-E-A-I-E-I-L-F-D-P-A-R-T-D-F-R-A-I-L-E-F-F-F-Q-I-H-D-P-S-T-K-N-R-Q-G-N-D-I-G-L-S-Y-R-S-A-I-Y-Y-V-D-D-E-Q-K-R-I-A-E-D-T-I-A-D-V-D-A-S-G-L-W-P-G-K-V-V-T-E-V-E-P-V-G-P-F-W-E-A-E-P-E-H-Q-D-Y-L-E-R-Y-P-D-G-Y-T-C-H-F-P-R-P-G-W-R-L-P-A-R-A-E-G"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-T-Q-T-S-E-N-V-T-W-L-T-Q-E-A-Y-N-Q-L-K-A-E-L-E-Y-L-S-G-P-A-R-T-E-I-A-A-K-I-A-A-A-R-E-E-G-D-L-R-E-N-G-G-Y-H-A-A-K-E-E-Q-G-K-Q-E-L-R-V-R-Q-L-T-Q-L-L-E-N-A-K-V-G-E-A-P-A-A-D-G-A-V-A-P-G-M-V-V-T-I-A-F-D-G-D-E-D-D-T-L-D-F-L-L-A-S-R-E-Y-A-S-A-D-I-E-T-Y-S-P-Q-S-P-L-G-S-G-V-N-G-K-K-V-G-E-D-A-Q-Y-E-L-P-N-G-K-L-A-S-V-K-I-L-K-A-E-P-Y-Q-G"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-T-S-R-T-D-E-T-A-N-A-T-A-L-G-Y-E-Q-A-R-D-E-L-I-E-V-V-R-R-L-E-A-G-G-T-T-L-E-E-S-L-A-L-W-E-R-G-E-E-L-A-K-V-C-R-T-W-L-E-G-A-R-K-R-L-D-A-A-L-A-E-E-E-N-A-G-D-D-S-E"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-N-D-I-G-P-L-E-L-V-T-L-V-V-L-A-V-L-V-F-G-P-D-K-L-P-K-M-I-Q-D-V-T-R-T-I-R-K-I-R-E-F-S-E-S-A-K-Q-D-I-R-E-E-L-G-P-E-F-K-D-F-E-F-E-D-L-N-P-K-T-F-I-R-K-Q-L-D-N-D-E-L-G-L-K-E-I-R-N-G-F-D-L-K-K-E-M-A-E-V-T-D-A-V-H-G-R-E-S-E-T-S-A-S-S-S-S-A-N-G-S-A-G-G-T-V-D-M-T-K-K-R-E-Q-L-E-A-D-E-R-P-P-F-D-A-D-A-T"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-R-D-I-H-P-E-Y-V-E-T-Q-V-S-C-T-C-G-A-S-F-T-T-R-S-T-I-S-S-G-T-V-R-A-E-V-C-S-E-C-H-P-F-Y-T-G-K-Q-K-I-L-D-T-G-G-R-V-A-R-F-E-A-R-F-G-K-A-A-A-A-K-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-I-L-V-Q-L-A-A-E-E-A-Q-N-P-L-I-P-E-V-P-E-L-V-I-G-L-L-A-F-A-I-V-F-F-V-L-G-K-K-L-L-P-N-I-N-K-V-L-E-E-R-R-A-A-I-E-G-G-I-E-E-A-E-A-M-K-V-E-A-Q-S-V-L-E-Q-Y-K-A-Q-L-A-E-A-R-H-E-A-A-R-L-R-Q-E-A-Q-E-Q-G-A-T-L-I-T-E-M-R-A-E-G-Q-R-Q-R-E-E-I-I-A-A-G-H-A-Q-L-E-A-D-R-K-A-A-A-Q-A-L-R-Q-D-V-G-T-L-A-T-D-L-A-G-K-L-V-G-E-S-L-E-D-H-A-R-Q-S-R-V-I-D-R-F-L-D-G-L-E-E-K-A-E-A-T-R"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-A-E-L-H-V-E-L-V-A-A-D-R-Q-V-W-S-G-E-A-T-L-V-V-A-R-T-T-S-G-D-I-G-V-M-P-G-H-Q-P-L-L-G-V-L-E-S-G-P-V-T-I-R-T-S-D-G-E-T-V-V-A-A-V-H-G-G-F-I-S-F-A-D-N-K-L-S-L-L-A-E-I-A-E-L-A-D-E-I-D-A-Q-R-A-E-R-E-L-E-R-A-K-A-E-G-D-A-T-A-E-R-R-A-D-V-R-L-R-A-V-S-A-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-P-Q-Q-L-R-Y-S-K-E-H-E-W-L-S-G-A-E-D-G-V-S-T-V-G-I-T-E-H-A-A-N-A-L-G-D-V-V-Y-V-Q-L-P-E-V-G-D-T-V-T-A-G-E-T-C-G-E-L-E-S-T-K-S-V-S-D-L-Y-S-P-V-T-G-E-V-V-E-A-N-Q-D-V-V-D-D-P-S-L-V-N-S-A-P-F-E-G-G-W-L-F-K-V-R-V-A-E-E-P-K-D-L-L-S-A-D-E-Y-T-E-F-S-G-S"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-P-G-I-T-R-E-E-V-A-H-L-A-R-L-A-R-L-E-L-K-A-E-E-L-D-H-F-A-G-Q-L-D-D-I-I-G-A-V-A-R-V-S-E-V-A-D-Q-D-V-P-P-T-S-H-P-L-P-L-T-N-V-M-R-A-D-E-V-R-P-S-L-T-P-E-Q-A-L-S-G-A-P-A-Q-E-Q-Q-R-F-K-V-P-Q-I-L-G-E-D"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-A-F-T-T-H-T-G-R-A-V-P-L-R-R-S-N-V-D-T-D-Q-I-I-P-A-H-W-L-K-K-V-T-R-D-G-F-E-D-G-L-F-E-A-W-R-K-D-E-S-F-I-L-N-R-P-E-R-T-G-A-T-V-L-V-A-G-P-D-F-G-T-G-S-S-R-E-H-A-V-W-A-L-Q-N-Y-G-F-K-A-V-I-S-S-R-F-A-D-I-F-R-G-N-S-L-K-N-G-L-L-T-V-V-L-E-Q-K-I-V-D-A-L-W-E-L-T-E-K-D-P-Q-A-E-V-T-V-D-L-E-A-R-E-V-R-A-E-G-I-T-A-A-F-E-L-D-E-N-A-R-W-R-L-L-N-G-L-D-D-I-S-I-T-L-Q-N-E-G-D-I-A-T-Y-E-A-K-R-P-S-H-K-P-R-T-L-Q-V"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-Q-L-V-V-A-R-I-G-R-A-H-G-I-K-G-E-V-T-V-E-V-R-T-D-E-P-E-L-R-L-G-P-G-A-V-L-A-T-D-P-A-S-V-G-P-L-T-I-E-T-G-R-V-H-S-G-R-L-L-L-R-F-E-G-V-R-D-R-N-G-A-E-A-L-R-N-T-L-L-I-A-E-V-D-P-D-E-V-P-E-D-P-D-E-Y-Y-D-H-Q-L-M-D-L-D-V-V-T-K-D-G-T-E-V-G-R-I-T-E-I-S-H-L-P-S-Q-D-L-F-V-V-E-R-S-D-G-S-E-V-Y-I-P-F-V-E-E-I-V-V-E-I-D-L-E-E-Q-R-A-V-I-D-P-P-P-G-L-I-D-D-R-A-E-V-D-S-S-D-T-E-A-A-T-E-A-D-A"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-H-L-L-D-S-V-D-S-A-S-L-R-S-D-L-P-A-F-R-P-G-D-T-V-N-V-H-V-R-V-I-E-G-N-R-S-R-V-Q-Q-F-K-G-V-V-I-R-R-Q-G-A-G-V-R-E-T-F-T-V-R-K-V-S-F-S-V-G-V-E-R-T-F-P-V-H-T-P-I-V-E-K-I-E-L-V-T-R-G-D-V-R-R-A-K-L-Y-Y-L-R-E-L-R-G-K-A-A-K-I-K-E-K-R-E-S"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-E-E-T-L-L-E-A-E-E-K-M-E-K-A-V-V-V-A-K-E-D-F-A-A-I-R-T-G-R-A-H-P-A-M-F-N-K-I-V-A-D-Y-Y-G-A-L-T-P-I-N-Q-L-A-S-F-S-V-P-E-P-R-M-A-V-V-T-P-F-D-K-S-A-L-R-N-I-E-Q-A-I-R-D-S-D-L-G-V-N-P-S-N-D-G-N-I-I-R-V-V-F-P-E-L-T-E-E-R-R-K-D-Y-I-K-V-A-K-T-K-G-E-D-A-K-V-S-I-R-S-V-R-R-K-A-K-D-A-I-D-K-L-I-K-D-G-E-V-G-E-D-E-G-R-R-A-E-K-E-L-D-D-T-T-A-K-Y-V-A-Q-V-D-E-L-L-K-H-K-E-A-E-L-L-E-V"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-T-T-Q-S-E-R-L-R-E-L-L-E-P-L-V-G-S-Q-G-L-D-L-E-G-I-E-V-E-S-V-G-R-K-R-V-L-R-V-V-V-D-S-D-E-G-A-D-L-D-A-I-A-D-V-S-R-A-L-S-A-K-L-D-E-T-D-A-M-G-E-G-E-Y-T-L-E-V-G-T-P-G-A-E-R-A-L-T-E-H-R-H-Y-V-R-A-V-D-R-L-V-R-F-Q-L-T-E-G-D-E-L-V-A-R-I-L-T-V-D-D-A-G-L-D-L-E-V-P-G-V-K-G-R-K-A-T-T-R-R-L-A-F-E-D-I-A-K-A-R-V-Q-V-E-F-N-R-K-D-K-K-D-M-T-E-E-E-E-A"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-D-N-A-R-A-K-R-L-A-D-L-I-R-E-V-V-A-Q-K-L-Q-R-G-I-K-D-P-R-L-G-S-Q-V-T-I-T-D-T-R-V-T-G-D-L-R-E-A-T-V-F-Y-T-V-Y-G-D-D-E-E-R-A-A-A-A-A-G-L-E-S-A-K-G-V-L-R-S-A-V-G-A-A-A-G-V-K-F-T-P-T-L-T-F-V-A-D-A-L-P-D-T-A-K-T-I-E-D-L-L-D-K-A-R-A-S-D-A-K-V-R-E-V-S-A-G-A-Q-F-A-G-D-A-D-P-Y-R-K-P-E-S-D-D-E-S-D-T-A-A-K-T-D-G-D-A-A-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-D-A-A-T-K-K-Q-I-I-T-E-F-G-T-K-E-G-D-T-G-S-P-E-V-Q-V-A-M-L-S-R-R-I-S-D-L-T-E-H-L-K-T-H-K-H-D-H-H-S-R-R-G-L-L-I-L-V-G-Q-R-R-R-L-L-Q-Y-L-A-K-K-D-I-Q-R-F-R-A-L-V-D-R-L-G-I-R-R-G-A-A-G-A-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-R-H-P-D-S-R-V-V-D-S-R-T-T-D-D-G-T-S-I-R-R-R-R-Q-C-P-D-C-S-R-R-F-T-T-V-E-T-C-S-L-M-V-V-K-R-S-G-V-T-E-P-F-S-R-T-K-V-I-N-G-V-R-K-A-C-Q-G-R-P-V-T-E-D-A-L-A-Q-L-G-Q-R-V-E-E-A-V-R-A-T-G-S-A-E-L-T-T-H-D-V-G-L-A-I-L-G-P-L-R-E-L-D-L-V-A-Y-L-R-F-A-S-V-Y-R-A-F-D-S-L-E-D-F-E-A-A-I-A-E-L-R-E-E-Q-R-E-R-P-A-V-D-D-E-D-H-E-D-A-G-A-E-R-Q-G-T-D-R-G-S-G-G-T-V-E-V-P-V-P-A-T-V-A-D"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-R-G-G-P-V-N-S-H-D-V-T-D-E-Q-W-E-G-L-A-Q-V-V-P-L-R-G-R-D-A-W-P-S-A-V-G-H-R-S-I-P-E-A-Q-T-E-A-R-R-R-F-V-V-L-R-V-N-I-F-A-D-A-R-D-V-A-E-T-L-M-R-G-I-P-V-L-L-D-L-T-S-A-E-T-E-V-A-K-R-V-L-D-F-S-T-G-V-V-F-G-L-A-S-G-M-H-R-V-D-R-N-V-F-L-L-T-P-P-G-T-E-V-Q-G-L-M-E-G-V-G-V-P-G-I"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-T-V-P-H-P-E-S-V-G-E-P-G-I-A-V-R-A-P-A-R-R-R-S-A-W-H-G-Q-A-P-V-V-A-V-V-A-L-G-G-G-I-G-G-T-A-R-Y-A-A-A-L-L-W-P-T-Q-S-G-G-F-P-W-T-T-F-W-V-N-V-V-G-C-A-V-I-G-V-F-M-V-V-I-T-D-V-W-P-A-H-R-L-V-R-P-F-F-G-T-G-V-L-G-G-F-T-T-F-S-T-Y-A-V-D-I-Q-K-L-V-D-A-G-H-P-R-T-A-L-A-Y-L-A-A-T-L-L-A-A-L-A-A-V-R-L-A-A-T-A-A-R-R-V-L-V-R-R-R-R"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-W-L-L-V-I-A-G-A-M-V-G-A-P-L-R-Y-V-T-D-R-M-V-Q-L-R-H-D-A-V-F-P-W-G-T-F-A-I-N-V-T-G-C-L-V-L-G-L-L-T-G-A-A-S-A-G-V-A-S-P-H-L-E-L-L-L-G-T-G-L-C-G-A-L-T-T-Y-S-T-F-S-Y-E-T-L-R-L-T-E-T-G-A-G-F-Y-A-A-A-N-A-I-A-S-V-A-A-G-L-G-A-A-F-A-G-V-W-F-A-Q-A-L-W-A"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-T-K-N-K-N-V-I-E-V-E-G-K-V-V-E-C-L-R-S-A-M-F-T-V-E-L-E-N-G-H-Q-V-L-A-H-I-S-G-K-I-R-K-N-Y-I-K-I-M-L-E-D-R-V-L-V-E-L-P-P-Y-D-L-T-R-G-R-I-V-F-R-Y-R-N"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-M-S-T-E-T-V-P-P-V-K-R-V-Q-G-H-K-G-Y-K-N-R-R-R-L-S-R-E-L-A-L-Q-G-I-Y-Q-W-Q-V-T-G-G-N-A-R-D-I-G-M-Q-L-Q-Q-V-S-F-F-S-K-A-D-G-P-Y-F-S-D-L-L-Q-G-V-L-E-H-A-A-D-L-Q-T-Q-I-Q-P-H-L-D-R-Q-I-A-E-L-S-P-V-E-C-S-I-L-L-I-G-T-Y-E-M-V-Y-R-P-E-I-P-C-R-A-I-I-N-E-A-I-E-L-A-K-S-Y-G-G-T-D-G-H-K-Y-V-N-G-V-L-D-K-L-A-T-R-L-R-A-V-E-L-Q-H-P-P-A-R-N-K-D-S-G"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-S-Y-Y-D-N-I-L-E-I-D-S-N-L-D-G-N-G-L-C-I-G-I-V-M-S-R-F-N-I-D-V-S-E-G-L-L-G-A-C-T-A-E-L-T-R-L-G-V-Q-E-A-D-I-V-L-T-T-V-P-G-A-L-E-I-P-V-A-L-Q-K-L-A-E-S-D-R-F-D-A-L-I-A-L-G-A-V-I-R-G-E-T-Y-H-F-E-V-V-A-N-E-S-A-R-G-L-A-A-V-G-R-E-Y-N-I-P-I-A-N-G-I-L-T-T-D-D-E-D-Q-A-T-A-R-M-A-E-K-G-G-E-T-A-R-V-A-I-E-M-A-N-L-V-L-T-L-D-E-M-D-Q-S-A-P-T"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-S-L-N-K-V-M-L-I-G-N-L-G-R-D-P-E-I-R-Y-M-P-S-G-D-A-M-A-N-L-N-I-A-T-T-D-T-W-K-D-K-G-G-E-K-Q-E-R-T-E-W-H-R-V-V-M-F-G-K-Q-A-E-I-A-G-E-Y-L-K-K-G-S-Q-I-Y-I-E-G-R-L-Q-T-R-K-W-T-D-K-S-N-V-E-R-Y-T-T-E-I-V-A-D-R-M-Q-M-L-G-G-R-S-G-G-G-S-Y-D-P-P-A-D-R-D-H-D-Y-Q-S-Q-S-T-P-P-A-K-S-N-T-G-F-D-D-M-E-D-D-I-P-F"} +{"text": "### FUNCTION Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-G-T-N-Q-I-L-D-E-I-R-E-V-N-L-S-Y-L-L-L-A-Q-Q-M-L-R-E-D-R-I-A-A-M-Y-R-L-G-I-D-E-D-I-A-D-I-L-V-K-L-T-N-S-Q-L-L-K-M-A-G-S-N-M-L-L-C-R-F-R-F-D-D-S-L-I-A-E-I-L-T-S-H-K-Q-D-R-A-L-T-Q-S-H-A-A-I-L-M-A-G-L-P-A-E-K-I-S"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-A-Q-A-K-K-R-V-R-Q-T-A-T-R-R-E-R-N-F-G-L-R-S-K-L-R-T-A-I-K-G-V-R-K-A-V-A-A-G-D-K-N-V-A-E-V-V-F-R-K-A-V-S-V-I-D-S-V-A-S-K-G-I-I-H-K-N-K-A-S-R-H-K-S-R-L-S-G-A-V-K-A-M-G"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-P-T-R-N-M-P-L-T-K-N-P-V-E-S-P-D-H-E-Q-E-L-V-L-T-V-Q-Y-V-A-D-K-T-D-I-P-N-R-R-L-F-R-K-W-V-K-A-A-L-S-K-P-A-E-V-V-I-R-I-V-D-R-Q-E-G-E-I-L-N-R-D-F-R-G-K-S-S-A-T-N-V-L-T-F-V-Y-D-D-D-V-P-L-L-G-D-I-V-L-C-A-P-V-I-C-N-E-A-Q-Q-Q-G-K-D-L-T-A-H-Y-A-H-L-T-I-H-G-I-L-H-L-Q-G-Y-D-H-I-R-D-E-D-A-V-V-M-E-S-L-E-T-E-I-I-T-R-L-G-Y-P-D-P-Y-V-I-Q-H"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-V-E-D-C-L-E-V-I-P-N-R-F-D-M-T-L-A-A-T-V-R-A-R-Q-V-S-V-G-S-T-P-M-I-D-S-E-R-D-K-P-I-V-I-A-L-R-E-L-A-Q-K-K-Y-G-E-E-I-L-N-T-L-R"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-T-E-S-Q-Q-Q-P-V-F-V-I-E-K-I-Y-V-K-D-L-S-L-E-I-P-H-A-P-R-I-F-L-E-R-E-A-P-E-I-N-F-Q-L-A-T-S-H-N-A-V-D-G-E-I-H-E-V-V-V-T-A-T-V-T-A-R-L-K-E-K-D-Q-V-M-F-L-V-E-A-H-Q-T-G-I-F-R-I-G-N-V-P-G-D-E-V-E-P-V-L-S-V-L-C-P-N-I-L-F-P-Y-L-R-E-T-I-S-D-T-V-T-R-A-G-F-P-P-V-I-L-N-P-V-N-F-E-A-I-Y-H-Q-K-K-Q-Q-E-T-A-G-E-Q-P-D-Q-P-A-D-T-I-T-R-H"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-T-L-S-L-N-D-I-K-R-V-A-K-L-A-R-I-E-I-S-E-T-D-A-Q-Q-N-L-V-R-L-S-G-I-F-D-L-I-E-Q-M-R-A-V-D-T-Q-G-I-K-P-M-S-H-S-Q-D-M-V-Q-R-L-R-E-D-I-V-T-E-S-D-Q-R-T-L-F-Q-S-V-A-P-Q-I-E-D-G-Y-Y-L-V-P-K-V-I-E"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-S-Q-L-V-R-K-P-R-K-A-K-R-T-K-S-K-V-P-A-L-E-S-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-N-G-Y-E-V-S-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-S-L-D-T-A-G-V-K-D-R-K-Q-A-R-S-K-Y-G-S-K-R-P-K-S-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-E-V-P-K-R-E-I-L-P-D-P-K-Y-H-N-I-E-L-A-K-F-V-N-V-L-M-T-R-G-K-K-S-V-A-E-Q-I-I-Y-G-A-L-N-H-L-E-K-K-T-G-K-D-P-V-E-V-F-T-Q-A-L-S-N-I-R-P-V-V-E-V-K-S-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-R-S-I-R-R-S-A-L-A-M-R-W-L-R-D-A-A-R-K-R-S-E-K-S-M-D-L-R-L-A-S-E-L-L-E-A-S-E-N-R-G-A-A-I-K-K-R-E-E-V-H-R-M-A-E-S-N-K-A-F-S-H-F-R-F"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-V-G-Y-I-K-L-Q-I-P-A-G-K-A-N-P-S-P-P-V-G-P-A-L-G-Q-R-Q-L-N-I-M-E-F-C-K-A-F-N-A-A-T-Q-K-M-E-P-G-L-P-V-P-V-V-I-T-A-Y-A-D-K-S-F-T-F-I-L-K-T-T-P-A-S-V-L-I-K-K-L-A-G-L-S-K-G-S-A-Q-P-H-V-D-K-V-G-K-L-T-R-S-Q-A-E-E-I-A-K-I-K-M-A-D-L-T-A-A-D-M-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-V-E-V-D-G-V"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-H-N-L-E-G-K-K-A-I-V-A-E-V-S-S-Q-V-A-K-A-Q-A-I-V-I-A-E-Y-R-G-L-G-V-D-Q-F-T-R-L-R-V-K-A-R-E-S-G-I-Y-F-R-V-I-K-N-T-F-A-R-R-A-V-A-D-T-P-F-S-G-L-A-E-S-M-V-G-P-L-A-Y-G-I-G-S-D-P-V-A-T-A-K-I-L-H-E-F-A-K-D-N-D-R-F-V-I-K-A-G-A-M-A-G-I-V-M-S-D-K-D-V-A-A-L-A-V-L-P-S-R-E-E-L-L-S-K-L-L-G-T-M-Q-A-P-I-A-K-F-V-R-T-L-N-E-V-P-S-K-F-V-R-G-L-A-A-V-R-D-K-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-I-A-K-A-E-I-L-E-S-I-A-N-M-T-V-L-E-L-S-E-L-I-K-E-M-E-E-K-F-G-V-S-A-A-A-A-T-V-A-V-A-A-A-P-A-A-A-A-A-V-E-E-Q-T-E-F-S-V-I-L-T-A-A-G-D-N-K-V-N-V-I-K-V-V-R-A-V-T-G-L-G-L-K-E-A-K-D-L-V-D-G-A-P-K-T-V-K-E-G-I-S-K-E-D-A-E-S-L-K-K-Q-L-V-E-A-G-A-G-C-E-I-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-E-P-L-P-R-I-L-V-S-E-L-C-K-F-V-M-A-I-L-N-I-L-R-Y-P-D-E-R-L-H-K-I-A-T-E-V-P-S-I-T-R-E-I-R-T-L-V-S-N-M-A-E-T-M-Y-A-A-P-G-I-G-L-A-A-T-Q-V-D-V-H-Q-R-I-I-V-I-D-V-S-E-T-R-D-E-L-L-V-L-I-N-P-E-I-I-A-S-S-G-N-A-E-T-Q-E-G-C-L-S-V-P-G-I-F-D-K-V-T-R-A-E-E-V-T-V-R-A-T-G-I-D-G-K-S-F-E-M-D-A-S-G-L-L-A-V-C-I-Q-H-E-M-D-H-L-M-G-K-V-F-V-E-Y-L-S-P-F-K-Q-S-R-I-L-S-K-L-K-K-Q-A-R-R-Q-I-A"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-S-K-L-A-E-R-F-P-Q-L-L-A-K-D-A-E-L-V-V-K-I-I-L-D-A-M-A-K-S-L-S-R-G-E-R-I-E-I-R-G-F-G-S-F-D-L-N-Y-R-P-S-R-V-G-R-N-P-K-S-G-E-K-V-H-V-P-E-K-Y-V-P-H-F-K-A-G-K-K-M-R-E-L-I-D-S-G-P-K-Q-H-K-V-L-D-R-V-T-G"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-K-V-N-P-P-L-A-W-H-P-A-P-V-S-A-P-V-D-L-H-W-W-L-T-H-R-G-S-L-T-R-L-I-Q-D-R-C-E-H-F-R-V-E-P-I-F-Q-A-L-A-T-A-C-I-D-E-L-E-V-M-N-L-R-R-Q-T-R-A-L-V-R-E-V-Y-L-R-C-N-E-T-P-V-V-F-A-H-S-I-V-R-K-E-H-L-R-G-A-W-R-G-L-S-R-L-G-N-Q-S-L-G-T-M-L-F-T-N-P-L-I-Q-R-T-P-L-A-F-K-K-L-K-P-H-H-P-L-F-E-R-A-C-K-R-L-Q-N-R-P-A-D-L-W-A-R-R-S-L-F-I-L-Q-H-Q-P-I-L-V-T-E-V-F-L-P-A-I-R-R-L"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-L-D-Y-F-R-S-S-K-S-K-T-A-S-V-A-K-E-R-L-Q-I-L-V-A-H-E-R-Y-Y-R-N-K-P-S-Y-L-P-Q-L-Q-E-E-L-M-Q-V-I-R-K-Y-V-Q-V-D-Q-D-A-I-S-V-K-F-E-Q-D-D-N-Q-E-T-L-E-L-N-I-I-L-P-D-S-Q-N-T-R-N-T-Q-Q-D-A-V-R-N-S-F"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-Q-I-E-I-S-A-N-S-R-K-L-H-G-T-G-A-N-R-R-L-R-S-Q-G-R-L-P-G-V-I-Y-G-G-N-G-D-A-Q-S-I-E-L-D-H-K-D-L-Y-Y-K-L-K-M-E-A-F-H-A-S-I-L-S-I-S-I-D-G-K-K-E-Q-V-L-L-R-D-V-Q-M-H-P-F-K-Q-Q-V-L-H-I-D-F-Q-R-V-R-Q-D-Q-K-I-H-V-K-V-P-L-H-F-I-N-A-D-I-A-P-G-V-K-L-S-G-G-M-I-S-H-V-A-T-E-I-E-I-S-C-L-P-K-D-L-P-E-F-I-T-V-D-L-S-G-M-T-A-G-S-T-L-H-L-S-D-L-I-L-S-E-N-V-E-I-P-A-L-L-K-G-D-N-L-P-V-A-T-L-I-A-K-R-G-E-A-G-E-S-S-E-E"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-E-L-P-V-R-L-V-V-G-L-G-N-P-G-E-K-Y-A-S-T-R-H-N-V-G-F-D-W-L-D-R-L-A-S-S-Q-R-V-A-F-T-L-E-T-R-F-R-G-L-C-A-R-I-M-L-A-D-T-D-I-W-L-L-K-P-Q-T-Y-M-N-A-S-G-M-S-V-A-A-V-C-R-Y-Y-K-I-V-P-E-Q-M-L-V-V-H-D-E-L-D-L-Q-P-G-V-I-K-L-K-S-G-G-G-T-G-G-H-N-G-L-K-S-I-V-A-D-L-S-S-Q-V-F-W-R-L-R-I-G-V-G-H-P-G-D-R-N-Q-V-V-D-Y-V-L-H-P-P-R-R-E-E-A-A-L-I-D-E-A-I-D-H-S-M-Q-V-W-P-L-I-A-R-G-D-F-A-A-A-M-Q-R-L-H-T-R-Q-E-N"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-K-P-V-L-K-M-G-D-P-C-L-L-Q-P-A-R-R-V-D-Q-F-G-T-P-E-L-E-A-L-L-Q-D-M-Q-D-T-M-A-A-L-N-G-A-G-L-A-A-P-Q-I-G-V-S-L-Q-V-V-I-F-G-V-E-H-S-P-R-Y-P-D-A-E-S-V-P-F-T-V-L-I-N-P-V-L-T-P-L-T-E-Q-M-E-E-D-W-E-G-C-L-S-I-P-G-M-R-G-L-V-P-R-Y-T-R-L-R-Y-Q-G-V-D-A-A-G-A-S-I-D-R-T-V-T-G-F-H-A-R-V-V-Q-H-E-C-D-H-L-N-G-I-L-Y-P-M-R-I-N-D-L-R-K-F-G-Y-T-D-T-L-F-P-G-Q-T-I-A-D-D"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-A-A-D-Y-R-N-P-E-S-I-I-E-K-G-R-A-R-L-N-P-P-P-L-Y-K-V-I-L-I-N-D-D-F-T-P-M-D-F-V-V-K-V-L-R-H-F-F-L-M-N-E-E-M-A-T-K-V-M-L-K-I-H-I-E-G-A-G-I-C-G-I-Y-P-S-D-I-A-V-T-K-V-Q-Q-V-N-D-F-S-R-Q-N-Q-H-P-L-M-C-V-M-E-K-E"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-A-D-V-K-K-S-A-E-Q-K-M-Q-K-S-L-D-A-L-K-V-D-F-S-K-V-R-S-G-R-P-H-T-G-L-L-D-H-I-M-V-D-Y-Y-G-T-P-T-P-I-K-Q-L-A-N-V-T-L-A-D-A-R-T-I-G-I-I-P-W-D-K-K-I-F-S-A-I-E-K-A-I-R-D-S-D-L-G-L-N-P-M-T-V-S-D-M-V-R-V-P-M-P-P-L-T-E-E-R-R-K-D-L-T-K-I-V-K-T-E-A-E-A-A-R-V-A-M-R-N-I-R-R-D-A-N-A-H-L-K-E-L-L-K-D-K-L-I-A-E-D-E-D-R-R-A-Q-D-E-I-Q-K-L-T-D-R-Y-I-A-E-V-D-K-L-L-Q-T-K-E-A-E-L-M-A-V"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-W-K-P-I-L-A-I-A-L-G-S-T-L-G-G-L-L-R-W-G-L-G-L-K-L-N-N-L-F-P-D-V-P-P-G-T-L-V-A-N-L-I-A-G-Y-V-V-G-V-A-I-A-F-F-A-H-M-P-N-L-S-P-E-W-R-L-L-V-I-T-G-F-C-G-G-L-S-T-F-S-T-F-S-A-E-I-V-S-L-L-Q-R-G-L-Y-A-W-A-M-S-A-I-A-V-H-V-A-G-S-L-I-M-T-L-A-G-I-A-T-V-T-W-F-K-S-S"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-L-I-E-Q-L-E-R-E-E-I-E-R-L-G-K-T-I-P-D-F-S-P-G-D-T-L-V-V-N-V-N-V-V-E-G-D-R-K-R-V-Q-A-F-E-G-V-V-I-A-K-R-N-R-G-L-N-S-S-F-I-V-R-K-I-S-S-G-E-A-V-E-R-T-F-Q-T-Y-S-P-L-I-A-S-M-E-V-K-R-R-G-A-V-R-R-A-K-L-Y-Y-L-R-D-R-S-G-K-A-A-R-I-R-E-K-L-P-A-R-S-V-Q-Q-E-N-V-A-E-A-L-Q-P"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-V-V-L-G-R-I-A-G-P-H-G-I-R-G-Q-I-K-V-I-P-F-T-E-Y-V-D-G-L-M-E-Y-P-V-W-C-L-S-R-D-E-K-N-W-Q-I-V-R-P-A-T-F-F-I-H-D-N-L-L-I-V-T-L-T-G-Y-S-D-R-T-S-A-S-E-L-K-G-L-L-V-A-V-P-R-S-Q-L-P-P-L-S-K-D-G-E-D-G-Y-Y-W-T-D-L-I-G-I-S-V-V-N-M-Q-G-E-P-L-G-T-V-A-G-L-F-E-T-G-A-N-D-V-L-R-V-R-L-S-G-S-S-K-D-E-L-I-P-F-V-D-Q-V-I-R-Q-V-D-L-E-S-R-Q-I-T-V-D-W-E-L-G-Y"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-D-M-T-S-A-S-S-G-T-V-L-A-F-D-F-G-K-R-R-I-G-V-A-I-G-E-H-E-L-R-M-A-H-P-L-T-T-I-D-Q-S-M-T-R-P-R-F-E-K-I-A-E-L-I-E-A-W-Q-P-V-L-L-V-V-G-L-S-V-H-A-D-G-T-E-H-E-I-T-R-L-C-R-R-F-A-R-R-L-E-G-R-F-R-I-P-V-A-L-A-D-E-R-Y-T-T-V-I-A-R-S-V-L-E-E-V-G-V-T-G-K-K-Q-R-P-M-L-D-Q-I-A-A-Q-H-I-L-Q-T-Y-F-D-L-S-H-A-A-S"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-K-N-R-T-N-Y-P-P-L-I-L-G-S-S-S-V-Y-R-C-E-L-L-Q-R-L-Q-I-P-F-E-T-A-S-P-A-V-D-E-F-A-L-P-G-E-A-P-G-T-T-A-L-R-L-A-K-E-K-A-H-A-V-A-K-L-F-P-D-A-L-I-I-T-A-D-Q-V-A-A-L-G-E-I-Q-L-G-K-P-L-S-H-E-N-A-V-Q-Q-L-R-L-M-R-G-R-E-V-I-F-H-S-A-L-C-L-F-N-S-R-T-T-R-L-Q-A-R-V-I-P-C-S-V-K-Y-R-E-L-S-D-S-Q-I-E-H-Y-L-A-K-E-Q-P-Y-H-C-A-G-S-A-K-A-E-G-L-G-I-A-L-I-E-R-I-T-G-E-D-P-N-A-L-I-G-L-P-L-I-A-L-V-E-M-L-M-E-E-E-V-E-L-F"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-S-A-K-P-H-E-V-R-H-E-W-F-V-V-D-A-T-D-K-V-L-G-R-L-A-A-A-I-A-H-R-L-R-G-K-H-K-P-I-Y-T-P-H-V-D-T-G-D-Y-I-V-V-I-N-A-D-K-L-R-V-T-G-N-K-A-E-D-K-K-Y-Y-R-H-S-G-Y-P-G-G-I-Y-E-T-T-F-K-K-M-H-E-R-F-P-T-R-P-L-E-K-A-V-K-G-M-L-P-K-G-P-L-G-Y-A-M-I-K-K-L-K-I-Y-A-G-D-T-H-P-H-A-A-Q-Q-P-Q-P-L-E-I-N-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-Q-V-D-I-K-L-L-D-P-R-L-Q-D-V-F-P-G-Y-A-T-P-G-S-A-G-L-D-L-R-A-C-I-D-E-R-M-E-I-H-P-G-E-T-L-L-I-P-S-G-I-A-I-H-L-A-D-P-G-F-A-A-M-V-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-Q-I-L-V-S-C-W-N-R-G-Q-A-G-F-T-L-D-P-M-E-R-I-A-Q-L-V-I-V-P-V-V-Q-A-G-F-N-V-V-E-N-F-Q-P-S-Q-R-G-E-Q-G-F-G-S-T-G-K-C"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-F-C-G-A-E-D-T-S-V-V-D-S-R-I-S-E-E-G-A-R-I-R-R-R-R-R-C-V-E-C-E-K-R-F-T-T-Y-E-T-V-E-L-R-F-P-Q-V-I-K-Q-D-G-N-R-V-E-F-N-R-E-K-L-Y-T-S-F-A-R-A-L-H-K-R-P-V-P-T-G-Q-V-D-A-A-I-E-R-I-L-Q-K-L-L-G-S-G-V-Q-E-I-S-S-R-T-I-G-E-W-V-M-Q-E-L-Y-S-L-D-K-V-A-Y-I-R-F-A-S-V-Y-R-S-F-E-D-V-G-D-F-Q-E-V-I-R-E-V-Q-S-S-P-Q-N-G-D-G-P-S-S"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters ### SEQUENCE -M-G-T-T-I-H-E-E-T-S-A-A-Q-P-P-L-N-F-T-D-G-A-A-S-K-V-K-E-L-I-E-E-E-D-N-Q-A-L-K-L-R-V-F-V-S-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-I-V-N-E-D-D-F-V-M-E-K-Q-G-V-K-L-L-V-D-S-M-S-F-Q-Y-L-V-G-A-E-I-D-Y-Q-E-S-A-Q-G-A-Q-F-V-I-K-N-P-S-A-A-S-T-C-G-C-G-S-S-F-S-V"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-R-N-G-Y-R-A-N-V-G-I-I-L-L-N-S-Q-N-Q-V-F-W-G-K-R-A-R-Q-D-S-W-Q-F-P-Q-G-G-I-K-S-G-E-T-P-T-E-A-M-Y-R-E-L-A-E-E-T-G-L-Q-P-V-H-V-E-I-L-G-R-T-R-E-W-L-R-Y-D-V-P-A-C-W-T-R-R-D-W-R-K-N-Y-R-G-Q-K-Q-I-W-F-L-L-R-L-L-G-R-D-S-D-V-S-L-E-T-C-A-H-P-E-F-D-A-W-R-W-N-Q-Y-W-V-E-L-E-S-V-V-E-F-K-R-Q-V-Y-R-Q-A-L-T-E-L-S-R-L-L-D-H-E-A-G-L-G-N-D-R-A-Y-R-E-P-L-E-P-V-E-K-N-R-K-K-S-S-D-T-R-Q-S"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-K-T-G-G-K-Q-Y-R-V-E-V-G-N-K-L-K-V-E-T-L-P-A-E-V-G-S-D-I-Q-L-D-Q-V-L-M-I-A-D-G-E-A-I-S-A-G-A-P-L-L-D-Q-A-K-V-S-A-T-V-V-S-H-G-R-H-D-K-I-R-I-F-K-M-R-R-R-K-H-Y-R-K-Q-Q-G-H-R-Q-N-Y-T-E-I-Q-I-T-G-I-S-A"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-G-V-K-G-Q-L-L-Q-D-P-F-L-N-I-L-R-K-E-R-I-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-D-S-F-D-Q-Y-V-V-L-L-K-N-S-V-T-Q-M-V-Y-K-H-A-I-S-T-I-V-P-A-K-A-I-S-I-P-I-P-A-D-T-Q-T-E-Q-D-E-P"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-R-I-I-F-L-L-I-A-L-I-C-A-G-L-V-S-Y-A-L-Y-L-Q-L-A-D-G-L-L-P-C-P-L-C-I-F-Q-R-M-A-Y-W-L-V-G-I-T-A-L-F-A-F-I-H-H-P-Q-R-L-G-R-R-I-Y-C-G-L-I-I-L-F-S-L-A-G-A-I-V-A-G-R-Q-A-W-L-V-R-F-P-E-A-F-E-C-G-I-S-P-E-E-A-F-L-N-E-L-P-L-A-R-W-W-P-D-M-F-E-A-N-G-D-C-T-D-G-T-W-Q-F-L-S-L-T-I-P-D-W-S-L-L-I-F-L-A-F-S-L-I-A-G-L-L-W-R-S-R-S-I-S-S-S-N-L-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-R-K-K-S-S-S-N-K-E-E-T-A-L-H-P-P-P-E-N-F-E-T-A-T-A-E-L-E-Q-I-V-A-G-M-E-T-G-Q-M-S-L-E-D-A-L-S-A-Y-K-R-G-V-E-L-L-Q-Y-C-Q-N-I-L-K-N-S-Q-Q-Q-I-K-I-L-E-A-D-M-L-K-H-F-S-P-A-E-H-D-A-S"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-E-G-I-H-P-E-Y-H-E-I-T-V-T-C-S-C-G-N-E-F-K-T-R-S-V-L-S-K-P-L-H-I-E-V-C-S-S-C-H-P-F-Y-T-G-K-Q-K-I-V-D-T-A-G-R-V-E-K-F-N-Q-K-Y-G-R-H-L-Q-K-Q-A-Q-T"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-K-A-R-H-K-K-I-L-K-L-A-K-G-Y-R-G-R-R-K-N-V-Y-R-I-A-K-Q-A-V-M-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-T-L-W-I-A-R-I-N-A-A-A-R-E-L-G-M-T-Y-S-T-F-M-N-G-I-R-K-A-G-I-S-L-D-R-K-I-L-A-D-L-A-V-F-D-K-V-A-F-E-K-I-T-N-Q-V-K-A-G-L-A-N"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-E-L-T-D-L-L-F-E-N-I-G-L-N-K-R-E-A-K-E-I-V-E-C-F-Y-E-E-M-R-A-A-L-Q-N-G-D-G-V-K-L-S-G-F-G-N-F-Q-L-R-T-K-P-Q-R-P-G-R-N-P-K-T-G-E-E-I-P-I-S-A-R-R-V-V-T-F-H-A-S-Q-K-L-K-S-M-V-E-A-N-Y-R-G-E-S-G-T-N"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-T-A-Q-E-L-R-V-G-N-V-F-M-L-G-K-D-P-M-V-V-L-K-T-E-F-T-K-S-G-R-N-S-S-V-V-K-M-K-Y-K-N-L-L-T-E-S-P-G-E-A-V-Y-K-A-D-D-K-F-D-I-V-V-L-D-K-K-E-V-N-Y-S-Y-F-A-S-P-M-Y-V-F-M-D-A-E-F-N-Q-Y-E-V-E-E-E-T-M-S-D-A-L-S-F-L-E-D-G-M-P-C-E-V-V-F-Y-N-D-K-P-I-S-V-E-L-P-N-T-V-V-R-E-I-I-Y-T-E-P-A-I-K-G-D-T-T-G-K-V-L-K-P-A-K-I-P-T-G-F-E-L-A-V-P-L-F-C-E-I-G-D-K-I-E-I-D-T-R-T-R-E-Y-R-S-R-V-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-R-D-F-S-R-T-V-R-V-A-D-Q-I-Q-R-E-L-A-L-L-I-Q-N-E-I-M-D-P-R-V-G-M-V-T-L-T-G-V-E-V-T-R-D-Y-A-Y-A-K-V-F-Y-T-T-L-G-G-D-E-N-I-Q-L-V-E-E-G-L-K-H-A-A-G-F-L-R-S-Q-L-A-G-K-I-R-L-R-V-V-P-Q-L-Q-F-V-Y-D-E-S-V-E-R-G-M-K-L-S-R-L-I-D-E-A-V-G-K-A"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-L-F-E-L-L-E-P-T-I-A-G-M-G-Y-E-L-V-D-I-E-Q-S-A-P-G-R-L-L-R-V-F-I-D-K-K-E-G-S-I-T-L-D-D-C-V-A-I-S-N-H-L-S-Q-L-L-A-V-E-N-I-D-Y-N-R-L-E-V-S-S-P-G-L-D-R-P-L-K-K-K-A-D-F-V-R-Y-M-G-E-S-A-R-I-R-L-R-I-A-L-Q-G-Q-R-N-F-V-G-T-L-V-E-V-N-D-D-V-L-T-L-N-A-D-G-K-L-L-Q-I-E-L-R-N-L-E-K-A-R-L-I-P-K-L"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-I-W-H-W-L-V-V-L-A-I-V-V-L-V-F-G-T-K-K-L-R-N-L-G-S-D-L-G-G-A-V-R-G-F-K-E-G-M-K-G-A-E-E-E-S-T-P-P-P-P-A-Q-Q-V-T-G-H-S-I-K-S-E-I-E-E-K-D-Q-T-K-V"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-S-F-A-E-L-V-V-V-G-I-V-A-L-I-V-I-G-P-E-R-L-P-A-V-A-R-T-A-G-Y-F-L-G-R-A-R-R-Y-V-D-Q-V-K-H-D-L-H-E-E-M-E-L-D-S-L-R-K-L-R-D-S-M-H-E-T-V-N-S-F-E-N-S-V-R-S-E-I-N-K-I-Q-E-T-T-E-T-Q-S-A-V-I-P-D-K-Q-P-P-F-E-K-A-A-E-N-I-E-P-V-N-T-S-E-T-K-T-S-S-A-P-A-E-P-R-Q-P-N-S"} +{"text": "### FUNCTION Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ### SEQUENCE -M-H-A-F-F-P-R-L-L-L-L-L-L-F-L-P-L-T-H-C-T-Y-L-P-S-L-P-Y-K-I-D-I-Q-Q-G-N-V-V-T-D-E-M-V-A-K-L-K-P-G-M-T-R-S-Q-V-R-F-T-L-G-T-P-L-V-M-D-I-F-H-G-D-R-W-D-Y-I-Y-R-T-A-P-G-G-R-V-A-E-E-K-K-L-T-V-F-F-Q-D-D-R-L-S-H-I-Q-G-D-F-P-Q-P-P-A-F-S-E-S-E-P-A-Q-N-F-F-S-P-E-Q-T-F-T-P-A-P-D-T-D-S-N-M-N-E-E-P-D-K-K-G-T-V-N-F-L-K-E-N-Q-T-N-F-Y-K-D-N-Q"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-V-P-A-E-L-K-Y-T-E-S-H-E-W-V-R-L-E-A-D-G-S-V-T-V-G-I-T-Q-H-A-Q-E-L-L-G-D-M-V-F-V-Q-L-P-D-V-G-R-A-L-A-Q-R-E-D-C-A-V-V-E-S-V-K-A-A-S-D-I-Y-A-P-L-G-G-E-V-I-A-V-N-S-E-V-E-T-S-P-E-K-I-N-E-D-C-Y-A-A-W-L-F-K-L-K-P-A-N-A-G-E-V-D-G-L-L-D-A-G-G-Y-Q-K-L-L-D-S-E-A-H"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-K-A-N-L-G-N-L-M-K-Q-A-Q-Q-M-Q-E-N-M-K-A-M-Q-E-K-L-A-A-I-E-V-E-G-Q-A-G-A-G-M-V-K-V-T-M-T-C-R-Y-D-V-K-R-V-N-I-D-S-S-L-I-G-D-D-K-E-M-L-E-D-L-V-A-A-A-V-N-D-A-V-R-R-V-E-T-V-T-Q-E-K-M-A-S-V-A-G-G-L-G-L-P-A-G-M-K-F-P-F"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-I-V-Q-N-K-K-A-F-H-D-Y-F-I-E-E-K-Y-E-A-G-I-V-L-E-G-W-E-V-K-A-I-R-A-G-R-A-Q-L-K-E-A-Y-I-L-I-R-K-G-E-L-F-L-I-G-S-H-I-S-P-L-A-T-A-S-T-H-V-N-P-D-P-V-K-T-R-K-L-L-L-H-A-S-Q-I-R-E-L-I-G-K-V-E-R-A-G-Y-T-L-I-P-L-D-M-H-Y-K-S-G-R-I-K-L-E-I-G-L-A-R-G-K-K-Q-Y-D-K-R-E-T-E-K-R-K-E-W-E-R-D-K-Q-R-L-L-R-I-R-R-S-S-D"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-V-K-P-S-L-K-I-R-K-K-V-K-K-N-V-V-E-G-V-A-H-I-H-A-S-F-N-N-T-I-V-T-I-S-D-R-Q-G-N-A-L-S-W-A-T-S-G-G-V-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-H-A-G-R-A-A-L-E-Y-G-V-K-N-L-E-V-R-V-K-G-P-G-P-G-R-D-S-A-V-R-A-L-N-A-T-G-F-K-I-T-S-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-I"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-T-I-K-P-G-I-G-S-A-K-P-K-R-R-V-G-R-G-I-G-S-G-L-G-K-T-C-G-R-G-H-K-G-Q-K-S-R-A-G-G-F-H-K-V-G-F-E-G-G-Q-M-P-L-Q-R-R-L-P-K-R-G-F-T-V-Y-G-K-K-Q-V-R-E-I-K-L-S-T-L-Q-L-I-D-L-S-E-F-N-P-S-V-L-Y-D-H-G-L-I-K-N-I-N-D-P-V-K-I-I-L-G-N-Q-L-I-K-R-A-I-K-I-K-D-L-I-I-S-R-G-A-K-E-A-V-E-Q-M-G-G-L-V-E-L-T-V-K-D-V-N-G-V"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-T-K-T-T-K-S-A-N-T-K-T-P-D-E-V-K-T-D-G-L-K-E-K-M-V-S-V-N-R-V-T-K-V-V-K-G-G-R-I-L-G-F-A-A-L-T-V-V-G-D-G-K-G-S-V-G-M-G-K-G-K-S-R-E-V-P-L-A-V-Q-K-A-M-D-E-A-R-Q-R-M-V-R-V-N-L-I-N-G-T-L-H-H-S-V-I-G-R-H-G-A-A-R-V-Y-M-Q-P-A-S-E-G-T-G-I-I-A-G-G-P-M-R-A-I-F-E-V-M-G-V-H-N-I-L-A-K-C-L-G-S-T-N-P-Y-N-I-V-R-A-T-L-D-G-L-S-K-V-Q-T-P-A-M-I-A-A-K-R-G-K-S-I-D-E-I-T-G-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-C-M-T-D-P-I-A-D-M-L-T-R-I-R-N-A-Q-S-A-E-Q-K-E-I-K-M-P-S-S-K-L-K-K-A-I-L-K-I-L-K-E-E-G-Y-I-E-N-F-Q-E-D-P-N-H-K-K-P-S-I-S-V-I-L-K-Y-F-N-G-E-P-V-I-T-S-I-S-R-V-S-K-P-G-L-R-S-Y-K-S-K-N-D-L-P-R-V-M-N-G-L-G-V-A-I-V-S-T-S-K-G-V-M-T-E-R-T-A-R-M-A-G-V-G-G-E-L-L-C-V-V-T"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-I-V-N-R-N-L-K-R-L-K-T-V-N-K-Y-A-A-R-R-A-E-I-V-S-I-L-R-D-A-G-S-D-I-E-A-K-A-S-A-R-D-L-L-Q-K-L-P-R-N-A-S-P-V-R-L-R-Q-R-C-A-L-T-G-R-P-R-G-V-F-S-K-F-G-L-G-R-I-K-L-R-E-I-A-M-R-G-E-I-P-G-L-I-K-A-S-W"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-L-L-K-V-A-D-N-T-G-A-R-T-V-M-C-I-K-V-L-G-G-S-K-R-R-F-A-G-I-G-D-V-I-K-V-A-V-K-D-A-A-P-R-G-R-I-K-R-G-E-V-Y-N-A-V-I-V-R-T-A-K-G-I-R-R-A-D-G-S-L-V-K-F-D-T-N-A-A-V-I-L-N-N-K-L-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-A-K-F-M-K-I-V-S-L-A-P-E-V-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-S-D-N-Q-S-K-T-L-I-G-Q-V-V-S-D-K-R-D-K-T-V-T-V-R-I-D-R-K-V-K-H-P-L-Y-G-K-I-V-T-R-S-S-K-Y-H-A-H-D-E-L-N-Q-Y-K-L-G-D-I-V-A-I-S-E-T-R-P-K-S-K-T-K-A-W-Q-V-V-R-V-I-K-V-N"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-A-R-T-K-F-R-K-Q-H-K-G-R-N-T-G-I-A-T-R-G-A-K-V-S-F-G-E-F-G-L-K-A-I-G-R-G-R-L-T-S-R-Q-I-E-A-A-R-R-A-M-T-R-H-I-K-R-G-G-R-I-W-I-R-V-F-P-D-K-P-V-S-Q-K-P-A-E-V-R-M-G-K-G-K-G-N-P-E-Y-Y-V-A-E-I-Q-P-G-K-M-L-Y-E-M-D-G-V-D-E-S-L-A-R-E-A-F-R-L-A-A-A-K-L-P-M-Q-T-T-F-V-I-R-H-L-G-S"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-S-A-V-L-R-S-V-R-L-S-A-Q-K-G-R-L-V-A-D-Q-I-R-G-L-Q-V-E-R-A-I-R-L-L-T-F-S-P-K-K-G-A-S-I-I-L-K-L-L-E-S-A-V-A-N-A-E-H-N-E-G-A-D-I-D-E-L-K-I-S-Q-I-F-I-G-Q-G-A-T-L-K-R-V-S-P-R-A-K-G-R-G-N-R-I-S-K-P-T-C-N-I-F-L-T-V-S-N-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-V-S-K-G-P-F-V-D-L-H-L-V-N-K-V-L-S-A-R-Q-N-N-D-K-K-P-I-K-T-W-S-R-R-S-T-I-L-P-D-F-I-G-L-T-I-S-V-H-N-G-R-Q-H-V-P-V-F-V-T-E-N-M-V-G-H-K-L-G-E-F-S-H-T-R-T-F-K-G-H-A-G-D-K-K-A-A-G-S-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-R-N-I-T-I-S-S-E-R-A-L-E-V-I-K-A-P-Q-I-S-E-K-S-T-F-I-A-E-K-T-K-Q-I-I-F-Y-V-S-R-D-A-N-K-T-E-I-K-S-A-I-E-Q-I-W-R-S-Q-N-I-Q-V-K-S-V-Q-V-V-N-V-K-G-K-K-K-R-F-G-R-Y-L-G-Q-K-S-D-W-K-K-A-F-V-S-L-K-G-D-R-E-I-D-F-T-D-V-K-L-F-E-D-K"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-K-I-R-I-R-L-K-A-F-D-Y-R-L-I-D-K-S-A-I-E-I-V-E-T-A-K-R-T-G-A-V-V-K-G-P-V-P-L-P-T-R-I-E-R-F-D-V-L-R-S-P-H-V-N-K-T-S-R-D-Q-F-E-I-R-T-H-L-R-L-M-D-I-I-D-P-T-D-K-T-V-D-A-L-M-K-L-D-L-P-A-G-V-D-V-E-I-K-L"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-T-T-R-Q-I-C-T-L-P-R-Q-C-K-L-R-K-A-D-E-F-R-A-V-L-R-N-R-I-V-F-E-S-L-S-L-R-L-Y-V-K-P-I-D-V-D-Y-A-R-I-G-L-I-V-A-K-R-V-E-R-K-A-V-R-R-N-R-I-K-R-L-I-R-E-A-F-R-R-H-R-Q-M-L-M-G-L-D-C-V-M-Q-L-R-H-P-V-E-L-L-D-S-T-R-I-Y-Q-E-A-V-M-L-F-N-K-A-A-R-Q-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-A-I-T-I-A-R-P-Y-A-E-A-V-F-K-L-A-R-E-S-G-S-L-F-S-W-S-E-T-L-D-A-V-N-S-I-V-R-E-S-Q-I-R-E-L-I-S-N-P-L-I-S-S-V-K-L-R-E-I-I-F-S-V-C-G-K-K-L-N-E-D-G-K-R-L-V-S-L-L-I-D-N-Q-R-L-L-V-M-P-Q-I-H-E-L-F-E-Q-L-K-A-Q-H-E-S-I-L-E-A-E-V-V-S-A-F-P-L-D-S-G-Q-L-E-K-L-V-S-I-L-E-A-K-F-Q-R-K-V-K-A-E-V-S-V-D-S-E-L-I-G-G-V-R-I-K-I-G-D-Q-V-V-D-S-S-V-H-G-K-L-E-A-M-A-T-A-L-K-S"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-I-N-F-T-L-I-S-Q-A-I-A-F-S-L-F-I-L-F-T-A-R-F-V-W-P-Y-L-L-R-A-I-E-E-R-Q-Q-K-I-A-D-G-L-A-A-G-E-R-G-K-K-E-L-E-L-A-S-Q-R-S-S-E-V-L-K-E-A-K-Q-R-A-S-E-I-V-I-Q-A-E-K-R-A-S-D-I-I-E-E-A-K-Q-N-A-R-I-E-G-E-K-I-I-A-G-A-K-A-E-I-Q-H-E-T-F-S-A-R-E-S-L-R-Q-Q-V-A-G-L-A-V-Q-G-A-S-K-I-L-R-R-E-V-N-A-K-V-H-A-D-L-L-A-S-I-E-A-E-L-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-I-V-H-P-D-Q-S-E-Q-V-S-A-M-T-E-R-Y-S-N-I-V-T-G-R-S-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-T-Y-P-I-Q-K-L-H-K-A-H-Y-V-L-M-N-I-E-C-D-Q-E-S-L-N-E-L-E-H-S-F-K-F-N-D-A-I-L-R-H-L-V-I-R-M-N-G-P-I-T-T-P-S-P-M-M-Q-E-G-K-S-R-P-P-H-S-S-D-E-D-S-E-N-T-A-P-A-K-A-K-T-A-D-S-P-G-E-D-T-R-T-T-E-E-S-D-P-K-P"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-I-P-N-P-D-P-E-S-S-I-N-R-N-Q-V-I-I-S-G-T-I-T-D-L-A-S-P-R-Y-T-P-A-G-L-M-I-A-E-F-K-L-S-H-C-S-N-Q-Q-E-A-G-I-Q-R-R-I-E-F-E-F-E-A-I-A-I-A-E-T-A-E-K-I-I-R-I-G-S-G-S-N-V-E-I-T-G-F-I-A-K-K-N-R-L-S-N-Q-L-V-L-H-V-R-D-T-R-I-I"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-N-R-P-L-F-K-R-K-K-F-C-R-F-T-A-E-G-I-K-H-I-D-Y-K-D-I-D-L-L-K-D-F-V-S-E-N-G-R-I-I-P-A-R-I-T-G-T-R-A-Y-Y-Q-R-Q-L-N-L-A-I-E-R-A-R-F-L-A-L-L-P-Y-T-D-Q-H"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-E-K-I-A-K-L-G-S-L-G-S-I-V-N-V-K-P-G-Y-A-R-N-Y-L-I-P-Q-G-K-A-R-R-V-T-E-K-V-I-A-E-F-E-A-Q-R-A-E-L-E-K-K-Q-S-E-I-L-A-A-A-S-A-Q-A-A-R-L-D-G-L-L-V-Q-I-S-Q-K-A-G-V-D-G-K-L-F-G-S-V-T-S-A-N-I-T-E-E-L-R-K-Q-D-F-P-V-E-K-S-M-I-R-M-P-E-G-Q-I-K-Q-I-G-D-Y-T-V-T-V-V-L-H-S-E-V-S-A-H-I-T-V-S-V-L-G-E-T-T-I"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-S-I-K-S-R-I-R-T-I-P-H-Y-P-H-E-G-I-M-F-R-D-I-T-T-L-L-K-D-P-A-G-L-R-S-T-I-D-G-I-V-Q-R-Y-Q-T-E-K-I-D-K-V-V-G-I-E-S-R-G-F-I-I-A-A-P-V-A-Y-A-L-S-A-G-F-V-P-V-R-K-Q-G-K-L-P-A-E-T-I-G-C-D-Y-Q-L-E-Y-G-Y-D-K-V-E-I-H-V-D-A-I-D-K-G-D-R-V-L-L-I-D-D-L-I-A-T-G-G-T-M-E-A-A-I-K-L-V-Q-E-A-G-G-E-V-I-E-C-C-F-V-I-D-L-P-D-I-G-G-S-R-R-L-R-Q-Q-G-H-R-L-F-S-L-C-S-F-E-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-V-T-T-D-Q-K-S-Q-V-M-R-D-Y-Q-R-A-A-G-D-T-G-S-P-E-V-Q-V-A-L-L-T-T-R-I-N-S-L-V-D-H-F-K-Q-H-V-K-D-H-H-S-R-R-G-L-L-R-M-V-S-R-R-R-K-L-L-D-Y-L-K-S-K-N-N-D-S-Y-R-A-L-I-E-R-L-G-L-R-K"} +{"text": "### FUNCTION CRISPR ### SEQUENCE -M-L-G-T-A-N-L-P-S-R-N-K-Y-K-A-K-A-T-I-L-H-M-N-R-N-L-Y-L-V-A-Y-D-I-C-N-P-R-R-L-R-Q-V-C-R-Y-L-T-G-Y-K-V-S-G-Q-K-S-V-F-E-I-W-V-T-P-T-E-L-H-T-I-R-T-E-L-D-K-L-M-D-T-Q-A-D-R-L-H-I-L-S-L-D-P-R-M-K-P-R-C-Y-G-N-A-S-T-F-T-V-Q-H-F-C-I-V"} +{"text": "### FUNCTION CRISPR ### SEQUENCE -M-P-A-D-H-F-L-K-R-Q-A-M-S-D-F-I-I-C-Y-D-I-T-D-P-R-R-L-G-R-L-Y-R-Y-L-I-K-R-A-V-P-L-Q-Y-S-V-F-L-F-R-G-D-D-R-Q-L-E-R-C-I-Q-D-A-I-E-L-I-D-E-K-Q-D-D-L-R-V-Y-P-L-P-G-R-G-L-K-A-R-I-G-R-P-T-L-P-E-G-I-Q-W-S-G-L-P-A-K-W"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-Q-D-S-N-N-L-I-W-I-D-M-E-M-T-G-L-N-P-G-T-D-R-I-I-E-V-A-L-V-V-T-D-A-Q-L-N-T-L-A-E-A-P-V-L-V-V-H-Q-P-D-D-I-L-N-G-M-D-K-W-N-Q-S-T-H-G-K-S-G-L-I-D-K-V-K-T-S-I-L-S-E-A-E-V-E-S-R-M-L-A-F-L-E-L-H-V-P-A-G-T-S-P-M-C-G-N-S-I-C-Q-D-R-R-F-L-A-R-S-M-P-K-L-E-S-Y-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-A-K-R-W-K-P-E-I-T-Q-G-F-N-K-Q-G-K-H-E-A-L-A-D-I-Y-D-S-I-E-E-L-K-Y-Y-R-Q-H-L-F-N-I"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-F-L-F-D-L-F-P-V-I-L-F-F-I-T-Y-K-V-Y-G-I-Y-N-A-T-A-V-A-I-I-A-T-F-V-Q-I-G-W-V-W-L-R-H-R-K-V-D-N-M-L-W-V-S-L-A-I-I-V-V-F-G-G-A-T-L-I-F-Q-D-E-T-F-I-K-W-K-P-T-V-L-Y-W-L-F-A-A-V-L-F-L-A-N-Q-I-F-E-K-N-L-I-R-V-M-M-K-D-Q-I-R-L-P-E-P-V-W-P-R-L-N-A-S-W-A-V-F-F-S-V-M-G-I-I-N-L-Y-V-A-Y-N-Y-S-T-D-T-W-V-N-F-K-L-F-G-F-M-G-L-M-F-A-F-V-I-L-Q-A-I-L-L-G-K-Y-V-E-K-S-D-D-Q-E-I"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-K-R-L-E-E-E-R-K-T-A-S-G-I-V-I-P-D-T-A-A-E-K-P-D-Q-G-E-I-I-A-V-G-K-G-K-T-G-E-D-G-K-I-R-A-L-E-V-K-V-G-D-R-V-L-F-G-K-Y-A-G-Q-A-V-K-I-K-G-E-E-F-L-V-M-R-E-E-D-I-M-G-V-I-E-G"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-S-Y-R-V-K-K-E-K-E-F-Q-Q-V-F-N-K-K-Q-S-C-A-N-R-R-F-V-V-Y-V-L-E-K-P-Q-Q-A-H-F-R-V-G-I-S-V-G-K-K-I-G-N-A-V-T-R-N-A-V-K-R-K-I-R-A-S-L-F-Q-L-K-D-R-I-S-P-E-I-D-F-I-V-I-A-R-P-G-L-E-K-L-S-S-E-E-V-K-A-N-L-T-H-V-L-N-L-A-K-I-L-D-V-R-E-G-I-E"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-K-I-I-K-N-A-T-A-G-T-V-E-S-S-D-I-M-I-T-V-Q-P-I-E-S-T-E-N-T-I-E-L-E-S-S-V-E-K-Q-F-G-N-Q-I-R-Q-V-I-T-T-T-L-E-H-L-D-V-Q-G-V-A-V-K-A-I-D-K-G-A-L-D-C-T-I-K-A-R-M-I-T-V-L-H-R-G-A-E-K-E-T-Y-D-W-K-E-L-D-S-W-N-V"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-A-K-K-Q-Q-A-M-I-A-K-Y-A-P-I-R-Q-A-L-K-E-A-G-D-Y-E-G-L-S-K-L-P-K-D-A-H-P-S-R-L-K-L-R-D-Q-T-D-G-R-P-R-G-Y-M-R-K-F-G-M-S-R-I-R-F-R-E-L-A-H-Q-G-L-I-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-I-K-E-F-K-E-F-I-M-R-G-S-V-L-D-L-A-V-G-V-V-I-G-S-A-F-T-A-I-V-T-Q-V-V-E-G-L-I-T-P-L-I-S-L-I-F-V-L-T-T-G-K-K-S-A-D-D-A-L-G-A-L-V-Y-K-V-E-G-V-E-F-N-I-G-S-V-I-S-A-L-I-T-F-L-I-T-A-F-V-L-F-L-I-V-K-A-A-N-K-M-K-N-R-G-K-K-E-E-A-A-E-E-E-V-V-P-T-S-E-D-Y-L-K-E-I-R-D-L-L-A-A-Q-T-P-P-A-E-T-V-K-T-D-S-T-F-T-E-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-T-M-K-D-I-I-R-E-G-N-P-T-L-R-A-V-A-E-E-V-P-V-P-I-T-E-E-D-R-Q-L-G-E-D-M-L-T-F-L-K-N-S-Q-D-P-V-K-A-E-E-L-Q-L-R-G-G-V-G-L-A-A-P-Q-L-D-I-S-K-R-I-I-A-V-H-V-P-S-N-D-P-E-N-E-T-P-S-L-S-T-V-M-Y-N-P-K-I-L-S-H-S-V-Q-D-V-C-L-G-E-G-E-G-C-L-S-V-D-R-D-V-P-G-Y-V-V-R-H-N-K-I-T-V-S-Y-F-D-M-A-G-E-K-H-K-V-R-L-K-N-Y-E-A-I-V-V-Q-H-E-I-D-H-I-N-G-I-M-F-Y-D-H-I-N-K-E-N-P-F-A-L-K-E-G-V-L-V-I-E"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-Y-Y-Q-E-T-K-I-R-N-P-K-R-E-D-T-K-S-L-Y-M-E-A-D-S-D-V-I-V-R-Q-L-V-E-E-N-T-P-Y-N-I-E-Y-V-Q-L-L-D-E-K-H-L-A-Y-E-Q-E-H-A-D-F-T-L-T-E-F"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-R-G-M-G-N-M-Q-G-M-M-K-Q-V-Q-K-M-Q-K-E-M-A-K-A-Q-E-A-L-N-E-K-E-F-I-G-E-A-T-N-Q-L-V-T-A-T-F-T-G-D-R-T-M-K-D-L-I-I-K-E-D-V-V-D-P-E-D-V-D-M-L-Q-D-L-V-I-M-A-V-N-D-A-L-V-K-I-E-K-E-T-E-A-T-L-G-K-Y-T-K-G-M-P-G-F"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-N-Y-P-E-P-I-A-K-L-I-E-S-Y-M-K-L-P-G-I-G-Q-K-T-A-T-R-L-A-F-Y-T-I-D-M-K-E-E-D-A-N-A-F-A-K-A-L-I-S-V-K-R-D-L-H-F-C-S-I-C-G-N-I-T-E-E-D-P-C-E-I-C-Q-D-K-N-R-D-R-S-I-I-L-V-V-E-E-P-K-D-V-M-S-M-E-K-M-R-E-Y-Q-G-L-Y-H-V-L-H-G-V-L-S-P-M-E-G-T-G-P-E-D-I-N-I-A-S-L-I-K-R-L-H-D-D-E-V-K-E-V-I-I-A-T-N-A-T-T-E-G-E-A-T-A-M-Y-L-S-R-L-I-K-P-A-G-I-T-V-T-R-L-A-H-G-L-S-V-G-S-D-I-E-Y-A-D-E-I-T-L-L-K-A-V-E-G-R-R-E-I"} +{"text": "### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-N-I-Q-E-T-V-L-N-I-L-E-D-I-T-G-T-D-E-V-V-N-N-Q-D-I-Q-L-F-E-E-G-L-L-D-S-L-A-T-V-Q-L-L-V-E-I-E-G-Q-L-G-I-Q-V-P-V-S-D-F-D-R-E-V-W-G-T-P-K-Q-I-I-Q-Q-V-E-A-L-Q"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-K-I-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-I-N-I-M-G-F-T-K-E-F-N-A-R-T-A-D-Q-A-G-L-I-I-P-V-V-I-S-V-Y-E-D-R-S-F-T-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-K-I-E-K-G-S-G-E-P-N-K-T-K-V-A-T-V-S-S-D-Q-V-K-E-I-A-E-L-K-M-A-D-L-N-A-A-D-V-E-A-A-M-R-M-V-A-G-T-A-R-S-M-G-I-I-V-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-E-A-A-I-A-K-K-E-T-L-V-Q-A-A-A-E-K-F-E-S-A-A-S-V-V-I-V-D-Y-R-G-L-T-V-E-E-V-T-N-L-R-K-Q-L-R-D-A-G-V-E-M-K-V-I-K-N-S-I-L-S-R-A-A-K-K-V-G-L-D-G-L-D-E-V-F-T-G-P-T-A-V-A-F-S-N-D-D-V-V-A-P-A-K-I-I-D-E-F-A-K-D-A-K-A-L-E-I-K-G-G-V-I-E-G-K-V-S-S-V-E-Q-I-T-A-L-A-K-L-P-N-R-E-G-L-L-S-M-L-L-S-V-L-Q-A-P-V-R-N-V-A-Y-A-V-K-A-V-A-E-K-N-E-E-V-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-N-I-E-N-I-V-A-E-L-E-T-A-T-I-L-E-L-S-E-L-V-K-A-I-E-E-K-F-D-V-S-A-A-A-P-V-A-V-A-G-P-A-A-G-G-A-A-E-E-Q-T-E-F-T-V-E-L-T-A-A-G-D-Q-K-V-K-V-I-K-A-V-R-E-A-T-G-L-G-L-K-E-A-K-A-V-V-D-G-A-P-A-P-V-K-E-A-V-S-K-E-E-A-E-A-L-K-A-A-L-E-E-V-G-A-S-V-T-V-K"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-L-T-L-Y-T-S-P-S-C-T-S-C-R-K-A-R-A-W-L-Q-E-H-E-I-P-F-K-E-R-N-I-F-S-E-P-L-N-I-E-E-L-K-A-I-L-I-M-T-E-D-G-T-E-E-I-I-S-T-R-S-K-V-F-Q-K-L-N-M-D-L-D-E-L-P-L-Q-D-L-L-E-L-V-Q-E-N-P-G-L-L-R-R-P-I-M-I-D-E-K-R-L-Q-V-G-F-N-E-D-E-I-R-R-F-L-P-R-D-V-R-Q-L-E-L-R-Q-A-Q-L-M-A-G-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-L-L-T-T-L-V-V-G-E-T-A-P-S-T-T-L-G-T-M-I-V-V-S-G-A-F-L-I-L-M-L-L-L-K-K-Y-A-W-G-A-I-V-D-I-L-T-Q-R-E-E-K-I-A-N-D-L-D-S-A-E-Q-S-R-V-A-A-A-K-M-E-K-E-R-Q-Q-Q-L-L-S-S-R-S-E-A-A-E-I-I-K-N-A-K-E-S-G-E-Q-T-R-Q-K-T-L-K-E-T-T-A-E-V-T-R-L-R-E-K-A-R-T-D-I-S-Q-E-R-E-E-A-L-S-S-V-K-N-E-V-A-D-L-S-L-Q-I-A-A-K-I-L-N-K-E-L-T-P-D-A-H-E-A-L-I-D-S-Y-I-E-S-L-G-K-A-N-E-T-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-L-D-K-Y-T-V-G-K-R-Y-G-K-A-L-F-E-L-A-V-E-K-N-Q-A-E-A-I-Y-Q-E-L-L-T-L-R-E-V-Y-H-Q-V-P-G-I-G-D-I-L-S-D-D-R-L-E-P-Y-E-K-D-S-I-M-E-K-L-V-T-G-F-S-E-M-M-Q-N-F-L-R-V-V-Y-E-Y-R-R-M-Y-D-L-L-L-M-I-D-E-Y-E-R-R-Y-D-E-H-Q-G-L-I-L-G-S-V-T-T-A-I-P-L-S-K-E-Q-H-Q-A-M-E-E-K-A-A-Q-L-L-G-Y-E-Q-A-H-L-V-N-L-I-D-P-S-I-V-G-G-V-V-I-E-A-N-H-Q-V-I-D-G-S-I-R-K-Q-L-E-H-M-Q-Q-K-L-L-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-D-S-L-T-V-N-V-V-T-P-N-G-L-V-Y-D-H-H-A-K-I-V-V-A-K-T-T-D-G-E-I-G-I-L-P-K-H-A-P-I-I-V-P-L-A-I-D-E-V-R-I-K-R-T-D-S-D-T-H-V-D-W-V-A-V-N-G-G-I-M-E-V-R-D-N-V-V-S-I-I-A-D-S-A-E-R-E-R-D-I-D-V-P-R-A-E-R-A-K-Q-R-A-E-R-L-I-E-E-A-K-A-K-D-D-R-D-Q-L-R-R-A-T-V-A-L-H-R-A-I-N-R-I-N-V-S-K-H-G"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-N-I-E-S-A-I-K-R-V-R-T-S-A-N-A-N-A-K-N-S-S-Q-T-N-A-M-R-T-A-I-K-K-F-E-E-A-V-A-A-G-A-D-N-V-D-A-L-Y-N-E-A-V-K-A-V-D-M-A-A-T-K-G-L-I-H-K-N-K-A-N-R-D-K-I-R-L-S-K-L-A-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-D-I-T-F-I-D-E-T-E-K-V-P-T-E-E-I-K-E-I-E-N-L-L-Q-F-A-A-G-F-L-E-I-A-E-D-T-E-M-S-V-T-F-T-D-N-A-G-I-Q-M-I-N-R-D-Y-R-G-K-D-M-P-T-D-V-I-S-F-A-L-E-D-E-G-E-D-E-L-P-I-I-F-D-D-E-E-L-A-E-L-P-R-N-L-G-D-L-I-I-S-T-E-R-A-A-E-Q-A-V-E-Y-G-H-T-L-E-R-E-M-G-F-L-A-V-H-G-F-L-H-L-N-G-Y-D-H-M-E-P-E-D-E-K-E-M-F-G-L-Q-K-E-I-L-D-A-Y-G-L-K-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-K-E-V-L-A-T-A-K-E-K-M-T-K-A-E-E-S-L-R-R-E-L-G-Q-I-R-A-G-R-A-N-A-S-L-L-D-R-I-Q-V-E-Y-Y-G-A-P-T-P-V-N-Q-L-A-S-I-N-I-P-E-A-R-V-L-M-I-T-P-F-D-K-N-S-I-A-D-I-E-K-A-I-Q-M-S-D-I-G-I-S-P-T-N-D-G-N-V-I-R-L-V-I-P-Q-L-T-E-E-R-R-K-E-L-A-K-D-V-K-K-E-A-E-N-S-K-V-A-V-R-N-V-R-R-D-A-M-D-E-L-K-K-A-Q-K-N-G-D-I-T-E-D-E-L-R-S-F-E-K-D-V-Q-K-L-T-D-D-S-I-K-N-I-D-A-I-T-A-E-K-E-Q-E-L-L-E-V"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-N-V-H-N-A-E-I-V-I-S-A-V-S-P-K-Q-Y-P-E-S-Q-L-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-L-I-N-R-K-N-L-A-R-T-S-G-K-P-G-K-T-Q-T-L-N-F-Y-L-I-E-D-A-L-H-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-T-E-R-A-K-W-G-K-M-I-E-T-Y-I-T-Q-R-E-Q-L-R-A-V-V-S-L-I-D-L-R-H-P-P-T-Q-D-D-I-Q-M-Y-E-F-L-K-Y-Y-D-L-P-V-I-I-V-A-T-K-A-D-K-I-P-R-G-K-W-N-K-H-E-S-V-I-K-K-A-L-N-F-D-K-Q-D-D-F-I-I-F-S-S-E-T-K-E-G-K-E-A-A-W-T-A-I-E-K-F-L"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-D-Y-L-N-V-G-K-I-V-N-T-Q-G-I-K-G-E-V-R-V-I-S-K-T-D-F-P-E-E-R-Y-Q-K-G-A-M-L-L-L-F-Q-E-K-K-A-P-I-E-L-V-V-K-S-H-R-K-H-K-N-F-D-I-L-S-F-E-G-H-P-N-I-N-D-V-E-K-Y-R-D-G-I-L-K-V-A-K-D-N-L-A-E-L-A-E-D-E-F-Y-Y-H-Q-I-I-G-A-T-V-Y-D-E-T-G-S-E-L-G-K-I-K-E-I-L-S-P-G-A-N-D-V-W-V-V-Q-R-P-K-K-K-D-L-L-L-P-Y-I-E-G-V-V-T-K-V-D-V-E-N-Q-R-I-D-V-D-I-P-E-G-L-I-D-D-E-N"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-P-L-I-Q-E-L-T-Q-E-Q-L-R-T-D-I-P-A-F-R-P-G-D-T-V-R-V-H-A-K-V-V-E-G-T-R-E-R-I-Q-L-F-E-G-V-V-I-K-R-R-G-A-G-I-S-E-T-Y-T-V-R-K-V-S-N-G-V-G-V-E-R-T-F-P-L-H-T-P-R-V-A-Q-I-E-V-V-R-Y-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-H-G-K-A-A-R-I-K-E-I-R-R"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-T-V-S-S-A-N-Q-L-V-Y-L-G-S-V-W-A-D-P-L-E-L-Q-N-L-C-T-S-A-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-S-D-V-W-K-T-I-P-T-A-T-V-R-F-P-A-T-G-F-K-V-F-R-Y-N-A-V-L-D-S-L-V-S-A-L-L-G-A-F-D-T-R-N-R-I-I-E-V-E-N-P-Q-N-P-T-T-A-E-T-L-D-A-T-R-R-V-D-D-A-T-V-A-I-R-A-S-I-S-N-L-M-N-E-L-V-R-G-T-G-M-Y-N-Q-A-L-F-E-S-A-S-G-L-T-W-A-T-T-P"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-P-Y-T-V-T-S-P-S-Q-L-V-Y-F-G-S-V-W-A-D-P-I-T-F-I-D-L-C-T-V-A-L-G-N-Q-F-Q-T-Q-N-A-R-T-T-V-Q-Q-Q-F-S-D-L-F-K-T-V-P-T-R-T-N-R-F-N-D-G-E-N-G-F-R-V-F-R-Y-N-S-T-L-D-P-L-I-S-A-L-M-N-S-F-D-T-R-N-R-I-I-E-V-D-N-P-A-N-P-N-T-S-E-V-A-S-A-T-Q-R-V-D-D-A-T-V-N-I-R-A-C-I-N-N-L-M-N-E-L-V-R-G-T-G-M-M-N-T-A-S-F-E-T-V-S-N-L-T-W-T-T-T-T-T-T"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-R-D-Y-I-A-S-I-P-D-Y-P-E-K-G-I-V-F-R-D-I-S-P-L-M-A-N-G-D-A-Y-R-E-A-T-K-Q-I-V-D-Y-A-K-E-K-R-I-D-M-V-V-G-P-E-A-R-G-F-I-V-G-C-P-V-A-Y-E-L-G-V-G-F-A-P-V-R-K-K-G-K-L-P-R-E-T-I-E-V-T-Y-D-L-E-Y-G-S-D-T-L-T-L-H-K-D-A-I-T-P-G-Q-R-V-L-I-C-D-D-L-L-A-T-G-G-T-I-K-A-T-I-E-L-V-E-Q-L-G-G-I-V-V-G-C-A-F-L-I-E-L-M-D-L-H-G-R-D-K-I-D-G-Y-D-I-V-T-L-M-E-Y"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-K-K-E-E-K-Q-E-E-L-Q-E-E-M-E-A-V-D-A-A-G-V-S-E-V-E-V-E-A-T-E-I-E-N-L-K-A-E-L-S-E-M-E-D-K-F-L-R-A-R-A-E-I-A-N-M-S-N-R-N-K-N-E-R-E-L-L-V-R-Y-R-S-Q-D-L-G-K-K-I-L-P-S-I-D-N-L-E-R-A-M-A-I-E-V-S-D-E-Q-G-E-S-L-K-K-G-I-S-M-V-L-E-S-I-T-V-A-L-K-E-E-G-I-E-E-I-P-A-M-G-E-T-F-D-P-N-L-H-Q-A-V-Q-T-V-P-A-S-E-E-T-P-A-D-T-I-V-E-V-L-Q-K-G-Y-K-L-Q-D-R-V-L-R-P-S-M-V-I-V-A-Q"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-N-Y-R-D-R-R-V-G-Q-E-I-M-R-E-V-N-D-I-L-N-K-R-I-R-D-P-R-V-Q-G-I-T-I-T-D-V-R-V-T-G-D-L-Q-Q-A-T-I-Y-Y-S-L-L-S-D-L-A-S-E-Q-Q-K-A-Q-Q-G-L-D-K-A-K-G-L-I-R-K-E-L-G-Q-R-L-T-L-Y-K-T-P-E-L-I-F-E-R-D-E-S-V-Q-Y-G-N-H-I-D-E-L-I-R-K-L-N-Q-G-E"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-S-A-V-E-T-V-T-K-L-V-T-P-I-L-E-E-Q-N-F-E-L-V-E-V-E-F-V-K-E-G-K-N-W-F-L-R-V-F-I-D-K-E-G-G-I-D-I-E-E-C-A-F-V-S-E-K-L-S-E-K-L-D-A-M-D-P-D-P-I-P-Q-A-Y-F-L-E-V-S-S-P-G-A-E-R-P-L-K-K-E-S-D-Y-E-Q-A-V-G-K-Y-I-H-I-S-L-Y-Q-A-V-D-G-E-K-Q-I-E-G-T-L-V-H-L-D-S-E-Q-L-T-L-S-V-K-I-K-T-R-V-K-E-M-T-F-E-R-K-N-I-A-K-A-R-L-A-I-Q-F"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-M-G-L-D-V-G-S-R-T-V-G-V-A-V-S-D-L-L-G-W-T-A-Q-G-I-E-I-I-R-I-N-E-E-E-E-N-F-G-F-E-R-L-G-E-L-V-K-E-Y-E-V-T-K-F-V-V-G-L-P-K-N-M-N-N-S-I-G-P-R-A-E-A-S-M-A-Y-G-D-K-I-Q-E-L-F-Q-L-P-V-D-Y-Q-D-E-R-L-T-T-V-Q-A-E-R-F-L-V-E-Q-A-D-A-S-R-A-K-R-K-K-V-I-D-K-L-A-A-V-M-I-L-Q-N-Y-L-D-A-H-S-R"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-A-R-V-E-S-F-E-L-D-H-N-T-V-K-A-P-Y-V-R-L-A-G-T-E-Q-N-G-D-A-L-V-E-K-Y-D-L-R-F-L-Q-P-N-K-D-A-L-P-T-G-A-L-H-T-L-E-H-L-L-A-V-N-M-R-D-E-L-K-G-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-I-M-W-D-Q-H-S-P-Q-E-I-R-D-A-L-V-N-V-L-N-K-V-I-N-T-E-V-V-P-A-V-S-A-K-E-C-G-N-Y-K-D-H-S-L-F-A-A-K-E-Y-A-K-I-V-L-D-Q-G-I-S-L-D-P-F-E-R-I-L"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-P-A-K-E-K-T-F-E-E-S-L-N-A-L-E-E-I-V-Q-R-L-E-R-G-D-V-P-L-E-E-A-L-A-A-F-Q-E-G-M-A-L-S-K-Q-C-Q-D-T-L-E-K-A-E-K-T-L-T-K-M-M-T-E-N-N-E-E-I-V-F-E-E-S-E-E-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-E-K-R-M-S-K-T-E-L-T-R-H-E-I-R-E-K-A-L-Q-A-L-F-P-L-D-F-N-A-D-L-T-K-Q-D-A-I-D-Y-A-L-A-Y-D-N-R-E-I-V-S-E-D-G-E-D-L-V-P-T-Y-L-D-L-L-V-G-G-V-C-S-R-K-A-E-L-D-E-V-I-T-N-H-L-G-N-N-W-S-M-Q-R-L-A-K-I-D-I-V-I-L-R-L-A-I-F-E-M-L-Y-V-S-D-V-P-N-I-V-A-L-N-E-A-V-E-L-S-K-K-Y-S-D-D-R-S-R-K-F-V-N-G-V-L-S-N-V-M-K-E-I-D-S-E-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-K-T-G-G-K-Q-V-K-V-E-V-G-Q-A-I-Y-V-E-K-L-N-V-E-A-G-E-K-V-V-F-D-E-V-I-L-V-G-G-E-S-T-K-V-G-A-P-T-V-A-G-A-T-V-E-G-T-V-E-K-H-G-K-Q-K-K-V-V-T-F-Q-Y-K-P-K-K-H-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-M-I-E-A-I-N-A"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-K-I-A-L-I-A-H-D-R-K-K-T-L-M-I-K-L-A-T-A-Y-K-H-I-L-E-K-H-E-L-Y-A-T-G-T-T-G-M-K-V-M-E-A-T-G-L-P-V-H-C-F-K-S-G-P-L-G-G-D-Q-Q-I-G-A-M-I-S-E-D-N-I-D-L-V-I-F-L-R-D-P-L-S-A-Q-P-H-E-P-D-V-T-A-L-I-R-L-S-D-V-Y-E-I-P-L-A-T-N-I-G-S-A-E-I-L-L-R-G-V-E-A-G-F-A-D-F-R-E-V-I-H-E-G-D-R-R-P-L-A-F"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-G-G-T-V-T-R-K-R-R-K-K-V-L-K-L-A-K-G-Y-Y-G-S-K-H-T-L-F-K-S-A-K-E-Q-V-M-N-S-Y-Y-Y-A-F-R-D-R-R-Q-K-K-R-D-F-R-K-L-W-I-A-R-I-N-A-A-A-R-M-N-G-L-S-Y-S-K-L-M-H-G-L-K-L-A-E-I-D-I-N-R-K-M-L-A-D-L-A-V-N-D-A-A-A-F-T-A-L-A-E-Q-A-K-D-A-L-S-K"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-T-I-A-K-D-M-M-V-N-D-G-I-R-A-R-E-L-R-L-I-G-Q-D-G-E-Q-L-G-V-K-T-K-A-E-A-L-Q-I-A-E-S-A-N-L-D-L-V-L-V-A-P-G-A-K-P-P-V-A-R-I-M-D-Y-G-K-F-R-F-E-Q-Q-K-K-E-R-E-A-R-K-K-Q-K-V-I-N-V-K-E-V-R-L-S-P-T-I-D-V-N-D-F-N-T-K-L-R-N-A-R-K-F-L-E-K-G-D-K-V-K-A-S-I-R-F-K-G-R-A-I-T-H-K-E-I-G-Q-K-V-L-D-R-L-A-E-E-T-A-D-I-A-T-V-E-Q-K-A-K-M-D-G-R-S-M-F-L-T-L-A-P-K-N-D-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-R-C-H-H-N-N-S-R-V-I-D-S-R-Q-A-D-D-G-R-A-I-R-R-R-R-E-C-E-N-C-S-Y-R-F-T-T-F-E-R-I-E-A-A-P-L-L-V-I-K-K-N-G-D-R-E-E-F-N-R-D-K-I-L-R-G-L-I-R-S-A-E-K-R-P-V-A-M-E-Q-M-V-Q-I-V-D-N-V-E-N-R-V-R-S-L-G-E-N-E-V-S-T-T-L-I-G-E-Y-V-M-E-D-L-V-N-L-D-E-I-A-Y-I-R-F-A-S-V-Y-R-Q-F-K-D-M-S-V-F-L-K-E-L-Q-D-I-V-D-K-A-K-S-S-S-P-D-S-E-N"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-L-I-P-T-V-I-E-Q-S-S-R-G-E-R-A-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-S-G-P-I-D-D-N-V-A-N-S-V-I-A-Q-L-L-F-L-D-A-Q-D-S-E-K-D-I-Y-L-Y-I-N-S-P-G-G-S-V-S-A-G-L-A-I-F-D-T-M-N-F-V-K-A-D-V-Q-T-I-V-L-G-M-A-A-S-M-G-S-F-L-L-T-A-G-Q-K-G-K-R-F-A-L-P-N-A-E-I-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-T-E-I-E-I-A-A-R-H-I-L-D-T-R-Q-R-L-N-S-I-L-A-E-R-T-G-Q-P-I-E-V-I-E-R-D-T-D-R-D-N-Y-M-T-A-E-Q-A-K-E-Y-G-L-I-D-E-V-M-E-N-S-S-A-L-N"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-A-I-T-E-E-Q-V-K-H-V-A-K-L-S-K-L-S-F-S-E-E-E-L-A-D-F-T-N-Q-L-D-K-I-I-D-M-V-E-L-L-E-E-V-D-T-T-G-V-P-F-T-S-N-V-N-E-S-I-N-V-M-R-E-D-V-A-T-P-G-M-D-R-K-E-L-M-R-N-V-P-E-S-E-N-G-Y-I-K-V-P-A-I-M-D-N-G-E-A-G-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-K-A-E-R-Q-R-L-I-K-Q-L-I-M-Q-Q-E-I-E-T-Q-D-E-L-I-T-R-L-E-E-I-G-V-R-A-T-Q-A-T-V-S-R-D-I-R-E-M-S-I-V-K-T-H-G-A-D-G-R-V-K-Y-A-I-F-S-Q-A-Q-G-T-S-S-E-E-K-L-R-E-S-V-K-D-S-V-V-R-M-E-R-V-Q-F-I-V-I-L-H-T-E-M-G-N-A-D-V-V-S-N-F-L-D-E-V-A-Y-P-E-V-A-G-T-V-A-G-A-D-T-I-I-V-I-T-R-S-E-E-D-A-E-H-F-I-E-R-I-E-N-M-I-F"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-A-A-S-D-L-K-A-G-M-T-F-E-Q-D-G-K-L-I-K-V-M-E-A-S-H-H-K-P-G-K-G-N-T-V-M-R-M-K-L-K-D-V-R-T-G-S-T-T-D-T-T-M-R-P-D-E-K-V-K-K-A-H-I-D-T-K-P-V-Q-Y-L-Y-S-Q-D-D-M-A-I-F-M-D-L-E-T-Y-E-Q-Y-E-V-P-T-A-L-I-E-E-E-L-K-Y-L-L-E-N-M-E-V-K-I-Q-F-Y-G-E-E-V-I-G-L-T-L-P-T-T-V-I-L-R-V-A-E-T-Q-P-S-I-K-G-A-T-V-T-G-S-G-K-P-A-T-M-E-T-G-L-V-V-N-V-P-D-F-V-E-A-D-E-L-L-E-I-N-T-A-E-G-T-Y-L-K-R-A-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-V-I-V-G-L-G-N-P-G-S-K-Y-K-E-T-K-H-N-I-G-F-I-T-L-D-E-I-A-Y-R-Q-N-V-S-F-N-N-S-N-F-E-A-D-I-A-E-F-F-I-G-T-E-K-V-L-L-V-K-P-L-T-F-M-N-E-S-G-R-S-V-G-P-L-L-T-Y-F-G-V-D-E-E-D-L-I-V-I-Y-D-D-L-D-L-E-I-G-K-I-R-L-R-Q-K-G-S-A-G-G-H-N-G-I-K-S-L-I-A-H-L-G-T-N-V-F-P-R-I-K-I-G-I-G-R-P-S-K-N-D-T-V-I-H-H-V-L-S-T-F-P-K-E-T-H-E-E-M-L-L-A-V-K-K-A-A-D-A-A-L-Y-A-C-E-G-H-T-F-V-E-T-M-N-Q-F-N-G-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-A-K-K-V-S-R-K-R-R-V-K-K-N-I-E-S-G-V-A-H-I-H-S-T-F-N-N-T-I-V-M-I-T-D-T-H-G-N-A-L-A-W-S-S-A-G-S-L-G-F-K-G-S-K-K-S-T-P-F-A-A-Q-M-A-A-E-A-A-T-K-V-A-M-E-H-G-L-K-T-V-D-V-T-V-K-G-P-G-S-G-R-E-A-A-I-R-S-L-Q-A-T-G-L-E-V-T-A-I-R-D-V-T-P-V-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-D-M-I-E-V-E-G-T-V-V-E-T-L-P-N-A-M-F-K-V-E-L-E-N-G-H-Q-V-L-A-T-V-S-G-K-I-R-M-H-Y-I-R-I-L-P-G-D-K-V-T-V-E-L-S-P-Y-D-L-T-R-G-R-I-T-Y-R-F-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-E-G-S-R-Q-V-R-N-R-V-G-R-G-T-S-S-G-N-G-K-T-A-G-R-G-Q-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-L-P-K-R-G-F-T-N-I-N-R-K-D-Y-A-V-V-N-L-D-T-L-N-R-F-E-D-G-T-E-V-T-P-V-V-L-K-E-A-G-I-V-K-N-E-K-A-G-I-K-V-L-A-D-G-E-L-T-K-K-L-T-V-K-A-A-K-F-S-K-S-A-Q-E-A-I-E-A-A-G-G-S-I-E-V-I"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-V-Y-I-D-P-K-H-L-E-L-E-D-R-V-V-A-I-N-R-V-T-K-V-V-K-G-G-R-R-L-R-F-A-A-L-V-V-V-G-D-K-N-G-H-V-G-F-G-T-G-K-A-Q-E-V-P-E-A-I-R-K-A-I-E-D-A-K-K-N-L-V-E-V-P-M-V-G-S-T-I-P-H-E-V-I-G-V-F-G-G-G-R-I-L-M-K-P-A-V-E-G-S-G-V-A-A-G-G-P-V-R-A-V-L-E-L-A-G-V-A-D-I-T-S-K-S-L-G-S-N-T-P-I-N-V-V-R-A-T-V-E-G-L-K-Q-L-K-R-A-E-E-V-A-A-L-R-G-K-S-V-E-E-I-I-G"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-T-K-P-D-K-N-K-T-R-Q-K-R-H-R-R-V-R-N-K-I-S-G-T-A-E-C-P-R-L-N-I-F-R-S-N-K-N-I-Y-A-Q-V-I-D-D-V-A-G-V-T-L-A-S-A-S-A-L-D-K-E-I-S-G-G-T-K-T-E-T-A-A-A-V-G-K-L-V-A-E-R-A-A-E-K-G-I-K-K-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-Q-A-L-A-E-A-A-R-E-N-G-L-E-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-V-V-V-L-P-A-G-V-E-I-K-Q-D-G-N-N-I-T-V-K-G-P-K-G-E-L-T-R-E-F-S-S-D-I-K-M-N-I-E-G-N-E-V-T-F-I-R-P-N-D-S-K-E-M-K-T-I-H-G-T-T-R-A-N-F-N-N-M-V-V-G-V-S-E-G-F-Q-K-A-L-E-L-I-G-V-G-Y-R-A-Q-V-Q-G-N-K-L-T-L-N-V-G-Y-S-H-P-V-E-M-T-A-P-E-G-V-T-F-E-V-P-A-N-T-Q-V-I-V-K-G-I-N-K-E-V-V-G-E-L-A-A-N-I-R-G-V-R-P-P-E-P-Y-K-G-K-G-I-R-Y-V-G-E-F-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-F-L-T-R-I-R-N-A-N-M-V-K-H-E-T-L-E-V-P-A-S-K-I-K-R-D-I-A-E-I-L-K-R-E-G-F-I-R-D-V-E-Y-I-E-D-D-K-Q-G-V-I-R-V-F-L-K-Y-G-K-N-E-E-R-V-I-T-N-L-K-R-I-S-K-P-G-L-R-A-Y-V-K-A-D-E-V-P-K-V-L-N-G-L-G-I-A-I-I-S-T-S-E-G-V-I-T-D-K-E-A-R-A-K-N-I-G-G-E-V-I-A-Y-V-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-E-K-Y-I-K-E-V-T-P-S-L-V-E-K-F-N-Y-S-S-V-M-Q-T-P-K-V-D-K-I-V-I-N-M-G-V-G-D-A-V-S-N-A-K-N-L-D-K-A-V-E-E-L-A-L-I-T-G-Q-K-P-L-I-T-K-A-K-K-S-I-A-G-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-V-T-V-S-L-P-R-V-R-D-F-H-G-V-S-K-K-A-F-D-G-R-G-N-Y-T-L-G-I-K-E-Q-L-I-F-P-E-V-D-Y-D-L-V-D-K-V-R-G-M-D-I-V-I-V-T-T-A-N-T-D-E-E-S-R-E-L-L-A-Q-L-G-M-P-F-Q-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-F-V-K-K-G-D-K-V-K-V-I-T-G-K-D-K-N-K-E-G-V-V-L-A-A-F-P-K-Q-D-K-V-I-V-E-G-V-N-V-V-K-K-H-Q-K-P-N-Q-A-A-P-Q-G-G-I-L-E-V-E-A-P-I-H-V-S-N-V-M-V-I-D-P-S-N-G-E-A-T-K-V-A-F-K-E-V-D-G-K-K-V-R-V-S-K-K-T-G-E-V-L-D-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-R-V-A-D-N-S-G-A-R-E-I-L-T-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-V-I-V-A-T-V-K-Q-A-T-P-G-G-V-V-K-K-G-E-V-V-K-A-V-I-V-R-T-K-S-G-A-R-R-A-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-R-D-D-K-S-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-N-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-T-E-E-R-N-Q-R-K-V-Y-Q-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-K-K-N-H-P-I-Y-G-K-R-M-K-Y-S-K-K-Y-K-A-H-D-E-N-N-T-A-K-V-G-D-I-V-K-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-L-E-V-V-E-E-A-V-I-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-H-R-R-E-F-R-G-K-M-R-G-E-A-K-G-G-K-E-V-A-F-G-E-W-G-L-Q-A-T-E-S-H-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-S-K-A-I-G-V-R-M-G-K-G-K-G-A-P-E-G-W-V-S-P-V-K-R-G-K-I-M-F-E-I-A-G-V-P-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-T-K-I-V-K-R-E-E-M-G-G-E-S-N-E-G"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-E-Q-I-T-S-A-K-A-T-A-K-T-V-R-T-S-P-R-K-A-R-L-V-I-D-L-I-R-G-K-S-V-A-D-A-I-S-I-L-K-F-T-P-N-K-S-A-G-I-I-E-K-V-L-M-S-A-V-A-N-A-E-N-N-F-D-L-D-V-E-S-L-V-V-S-E-A-F-V-N-E-G-P-T-M-K-R-F-R-P-R-A-K-G-S-A-S-P-I-N-K-R-T-S-H-I-T-V-V-V-T-E-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-V-D-D-H-L-M-K-K-V-E-A-Q-Q-G-A-E-K-K-K-V-I-K-T-W-S-R-R-S-T-I-F-P-S-F-V-G-F-T-I-A-V-Y-D-G-R-K-H-V-P-V-Y-I-Q-E-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-V-A-D-D-K-K-T-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-E-L-L-D-V-I-K-R-P-V-I-T-E-K-S-M-L-A-M-D-E-K-K-Y-T-F-E-V-D-T-R-A-N-K-T-L-V-K-Q-A-V-E-S-A-F-D-V-K-V-A-N-V-N-I-L-N-V-R-P-K-F-K-R-M-G-K-Y-A-G-Y-T-K-K-R-R-K-A-I-V-T-L-T-E-D-S-K-E-I-Q-L-F-E-A-A-E"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-K-Q-K-I-R-I-R-L-K-A-Y-E-H-R-I-L-D-Q-S-A-D-K-I-V-E-T-A-K-R-T-G-A-D-V-S-G-P-I-P-L-P-T-E-R-S-L-Y-T-V-I-R-A-T-H-K-Y-K-D-S-R-E-Q-F-E-M-R-T-H-K-R-L-I-D-I-V-N-P-T-P-K-T-V-D-A-L-M-K-L-D-L-P-S-G-V-N-I-E-I-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-A-K-R-D-V-L-P-D-P-I-Y-N-S-K-L-V-T-R-L-I-N-R-V-M-V-D-G-K-R-G-I-A-A-N-I-I-Y-N-S-F-D-I-I-K-E-S-T-G-N-D-P-L-E-V-F-E-Q-A-M-K-N-V-M-P-V-L-E-V-K-A-R-R-V-G-G-S-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-V-V-N-Y-A-R-L-R-G-E-H-T-M-E-E-R-L-A-K-E-I-M-D-A-A-N-N-T-G-A-S-V-K-K-R-E-D-T-H-K-M-A-D-A-N-R-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 ### SEQUENCE -M-R-D-Y-K-Q-L-N-G-L-A-L-A-Y-V-G-D-A-I-Y-E-I-Y-I-R-D-Y-L-V-S-L-G-Q-T-K-P-N-V-L-H-R-M-A-T-H-Y-V-S-A-K-A-Q-A-S-L-M-Q-A-M-L-A-G-E-M-L-T-E-E-E-E-V-M-Y-K-R-G-R-N-A-K-S-H-T-F-A-K-N-A-D-V-T-T-Y-R-V-A-T-G-F-E-S-L-M-G-Y-L-H-L-T-Q-Q-K-E-R-L-E-E-L-I-N-W-C-I-K-K-V-G-E-T-N-E-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-Q-D-V-K-G-K-G-K-K-G-D-V-K-E-V-P-T-G-Y-A-Q-N-F-L-I-K-N-G-Y-A-K-E-A-N-K-G-S-M-S-A-L-A-G-Q-K-K-A-Q-E-K-H-E-A-E-V-L-A-Q-A-K-E-M-Q-A-F-L-E-D-E-K-T-V-V-E-I-K-A-K-A-G-E-D-S-R-L-F-G-S-I-P-S-K-Q-I-A-E-A-L-N-K-Q-Y-N-V-K-L-D-K-R-K-I-E-L-A-N-P-I-R-S-L-G-Y-T-N-V-P-V-K-L-H-H-E-V-T-A-K-I-K-V-H-V-V-A-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Q-Q-R-R-G-G-R-K-R-R-K-V-D-Y-I-A-A-N-H-I-E-Y-I-D-Y-K-D-T-E-L-L-K-R-F-I-S-E-R-G-K-I-L-P-R-R-V-T-G-T-G-A-K-N-Q-R-K-L-T-I-A-I-K-R-A-R-I-M-G-L-L-P-F-V-S-D-E-Q"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-N-V-V-L-V-G-R-L-T-K-D-P-D-L-R-Y-T-A-S-G-S-A-V-A-T-F-T-L-A-V-N-R-N-F-T-N-Q-N-G-D-R-E-A-D-F-I-N-C-V-I-W-R-K-P-A-E-T-M-A-N-Y-A-R-K-G-T-L-L-G-V-V-G-R-I-Q-T-R-N-Y-E-N-Q-Q-G-Q-R-V-Y-V-T-E-V-V-C-E-N-F-Q-L-L-E-S-R-S-A-S-E-Q-R-G-T-G-G-G-S-F-N-N-N-E-N-G-Y-Q-S-Q-N-R-S-F-G-N-N-N-A-S-S-G-F-N-N-N-N-N-S-F-N-P-S-S-S-Q-S-Q-N-N-N-G-M-P-D-F-D-K-D-S-D-P-F-G-G-S-G-S-S-I-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-Q-D-T-K-Y-E-I-M-Y-I-I-R-P-N-I-D-E-E-A-K-T-A-L-V-E-R-F-D-T-I-L-K-D-N-G-A-E-V-I-E-S-K-D-W-E-K-R-R-L-A-Y-E-M-N-G-F-R-E-G-I-Y-H-I-V-N-V-T-S-P-S-T-A-G-A-I-N-E-F-D-R-L-A-K-I-N-D-D-I-I-R-H-M-I-V-K-V-E-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-N-Q-N-L-I-A-L-G-F-D-F-G-M-K-R-I-G-V-A-V-G-Q-T-V-T-H-S-A-N-A-I-A-I-L-K-A-Q-D-G-V-P-D-W-E-K-I-K-M-L-I-E-T-W-H-A-N-V-L-V-V-G-I-P-Y-N-M-D-G-S-E-Q-T-L-T-F-A-A-R-K-F-A-R-K-L-Q-M-R-F-G-L-P-V-S-M-V-D-E-R-L-T-T-I-E-A-K-R-Q-W-Y-E-Q-G-L-T-K-R-P-Q-H-L-D-N-Y-A-A-K-L-I-L-E-Q-W-L-Q-E-Q-K-N-E"} +{"text": "### FUNCTION Involved in stress response ### SEQUENCE -M-H-Y-K-H-I-L-A-A-I-D-L-S-P-R-S-Q-E-V-I-D-R-A-A-E-V-A-A-S-N-N-A-T-L-D-V-V-H-V-I-E-H-S-P-V-A-Y-G-G-E-F-S-I-P-I-N-V-N-L-E-Q-T-I-E-S-E-A-R-K-A-L-T-E-L-C-H-T-V-K-V-P-S-E-R-Q-H-T-L-S-G-V-V-K-H-M-V-I-E-L-A-E-K-L-N-I-D-L-I-V-V-G-T-H-G-H-H-G-L-D-K-L-L-G-S-R-A-N-A-I-L-H-V-A-T-C-D-V-L-A-V-W-M-K-E"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-L-H-L-T-L-A-R-P-Y-A-K-A-A-F-A-D-G-Q-K-A-N-Q-L-E-A-W-L-A-V-F-T-A-F-S-K-I-I-K-N-K-E-V-A-R-Q-I-I-N-P-K-F-S-D-K-E-I-K-T-L-L-F-D-L-I-Q-T-I-E-P-E-S-T-K-Q-L-K-D-K-I-D-H-F-L-Q-L-L-I-D-E-K-R-L-M-I-L-P-D-I-A-L-V-Y-Q-Q-L-L-N-K-Y-Q-G-I-I-E-A-S-V-T-Y-V-F-P-L-N-D-E-H-R-Q-Q-I-Q-K-Q-L-E-K-R-F-N-A-E-V-K-L-K-M-I-K-D-E-S-L-L-G-G-V-I-I-R-A-G-N-W-V-M-D-G-S-I-K-G-K-L-T-R-L-A-E-N-L-K-G"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-I-N-A-S-L-I-V-Q-M-L-V-F-V-V-F-I-G-L-T-M-K-F-I-W-P-P-L-T-K-A-L-E-A-R-R-K-N-I-A-D-G-L-A-A-A-E-E-G-R-K-E-L-E-L-A-E-I-K-S-K-E-Q-L-T-E-A-K-T-Q-A-A-H-I-I-E-Q-A-N-Q-R-A-N-H-I-V-E-E-A-K-N-K-A-R-E-E-G-A-H-L-I-Q-L-A-K-N-E-I-E-Q-E-Y-N-A-A-K-T-E-L-L-K-Q-I-S-T-I-A-V-A-G-A-Q-K-I-L-Q-R-E-V-D-K-A-S-N-D-R-L-V-D-E-L-V-S-E-I"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-N-A-L-A-Q-K-T-P-S-P-P-T-L-V-F-T-E-A-A-V-R-K-V-K-G-L-I-D-E-E-N-N-P-Y-L-N-L-R-V-F-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-A-I-N-S-D-D-L-V-I-E-K-Q-L-E-E-E-D-D-D-E-G-G-T-G-Q-M-A-L-V-K-L-L-V-D-P-L-S-L-Q-Y-L-Q-G-A-E-I-D-Y-R-E-D-V-S-G-A-Q-F-V-I-R-N-P-N-A-K-T-T-C-G-C-G-S-S-F-A-A"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-G-G-V-K-L-I-A-G-L-G-N-P-G-D-Q-Y-A-R-T-R-H-N-V-G-A-W-F-L-E-T-L-A-Q-Q-R-N-Q-S-L-A-K-E-N-K-F-H-G-F-V-A-K-C-N-D-Y-W-L-L-K-P-T-T-F-M-N-E-S-G-Q-A-V-A-A-L-A-H-F-Y-K-I-K-P-S-E-I-L-I-A-H-D-E-L-D-F-P-A-G-D-I-R-L-K-E-G-G-G-H-G-G-H-N-G-L-R-N-I-I-Q-H-L-G-S-S-D-F-Y-R-L-R-I-G-I-N-H-P-G-H-K-D-R-V-T-P-Y-V-L-S-P-P-S-E-N-D-R-I-A-I-L-A-A-I-E-K-G-L-R-L-I-P-E-L-V-Q-G-D-F-Q-K-V-M-R-E-L-H-S"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-T-H-S-T-N-E-F-R-G-G-L-K-V-M-V-D-G-D-P-C-S-I-I-D-N-E-F-V-K-P-G-K-G-Q-A-F-N-R-V-K-F-R-N-L-K-T-G-R-V-L-E-R-T-F-K-S-G-E-T-L-P-A-A-D-V-V-E-V-E-M-Q-Y-L-Y-N-D-G-E-F-W-H-F-M-T-S-E-N-Y-E-Q-H-A-A-S-K-E-A-V-A-E-A-K-Q-W-L-K-E-E-A-L-C-M-V-T-M-W-N-G-V-P-L-S-V-E-P-P-N-F-V-E-L-K-I-T-E-T-E-P-G-V-R-G-D-T-A-T-G-G-T-K-R-A-K-L-E-T-G-A-V-V-R-V-P-L-F-L-N-E-G-E-I-I-K-V-D-T-R-R-G-E-Y-V-S-R-A-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-A-T-Y-M-A-N-A-K-T-V-S-P-R-W-L-L-V-N-A-E-G-K-T-L-G-R-L-A-S-R-I-A-A-I-L-R-G-K-H-K-A-E-F-T-P-H-V-D-A-G-D-F-V-V-V-I-N-V-D-K-L-K-V-T-G-N-K-T-Q-D-K-Q-Y-H-H-H-S-G-Y-P-G-G-L-K-T-I-N-F-A-D-L-Q-A-K-K-P-Q-R-I-L-E-L-A-I-K-G-M-L-P-K-G-P-L-G-R-Q-L-Y-R-K-L-K-I-Y-A-G-D-Q-H-P-H-Q-A-Q-Q-P-E-L-I-D-L"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-E-F-P-A-E-L-Y-Y-S-K-N-H-E-W-M-R-K-E-S-D-E-T-F-T-V-G-I-T-D-H-A-Q-E-Q-L-G-D-L-V-F-V-E-L-P-E-T-N-I-H-V-D-A-G-D-E-V-A-V-V-E-S-V-K-T-A-A-D-V-Y-S-P-L-S-G-K-V-I-E-I-N-N-A-L-E-N-E-P-A-T-V-N-R-D-P-Y-G-D-G-W-L-Y-R-I-T-I-D-D-E-K-E-L-N-D-L-L-D-A-D-G-Y-Q-T-L-I-E-A-E-S"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-P-I-I-A-I-L-I-A-L-F-I-L-L-Q-Y-Q-L-W-F-A-A-G-G-I-V-S-V-H-H-L-N-E-N-I-N-H-Q-I-M-E-N-Q-K-L-K-D-R-N-T-A-L-L-A-D-I-D-D-L-K-H-G-A-E-A-I-E-E-H-A-R-N-D-L-G-M-I-K-K-N-E-V-F-Y-Q-I-V-K"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-A-E-Q-N-Q-R-T-N-T-P-D-N-G-P-E-F-A-I-Q-R-L-Y-I-K-D-L-S-F-E-A-P-R-S-P-Q-V-F-L-E-E-W-Q-P-E-L-N-M-D-L-A-T-K-V-N-D-L-G-E-D-N-H-E-V-V-L-T-V-T-V-T-V-T-M-K-E-S-H-I-F-L-A-E-V-Q-Q-G-G-I-F-T-I-K-N-F-P-K-E-E-M-R-P-M-L-G-S-F-C-P-N-I-L-Y-P-Y-A-R-E-A-I-T-D-M-V-V-R-G-G-F-P-Q-L-Y-L-A-P-V-N-F-D-A-L-F-E-Q-H-E-Q-S-E-E-G-N-S-G-T-E-D-R-V-H"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-Q-A-R-T-L-H-R-L-I-A-P-A-V-E-A-L-G-F-E-L-V-G-C-E-L-F-R-R-G-A-T-T-I-L-Q-V-F-V-D-K-P-G-G-I-G-L-D-E-C-A-K-V-S-R-Q-I-S-A-V-L-D-V-E-D-P-I-R-G-R-Y-T-L-E-V-S-S-P-G-L-E-R-P-L-Y-T-A-N-H-Y-R-R-F-I-G-N-K-A-K-I-R-L-R-E-P-R-E-G-Q-R-Q-F-R-G-M-V-V-A-V-D-N-E-E-Q-V-T-L-Q-L-D-N-K-I-L-K-V-S-L-G-E-I-E-K-A-N-L-I-A-D-F-E-G"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-Q-R-Q-Q-R-V-A-D-L-I-H-Q-Q-L-A-E-L-L-K-K-E-V-R-D-S-R-L-S-K-I-S-L-T-A-V-S-I-S-P-D-L-K-Q-A-K-V-F-Y-S-L-L-E-N-Q-N-E-K-E-V-Q-K-A-L-N-K-A-T-G-Y-L-R-H-L-L-A-Q-A-T-V-L-R-Y-V-P-K-L-E-F-V-Y-D-E-S-I-E-R-A-H-R-I-S-L-L-I-E-R-A-L-K-K-D-D-S-D-E-S-S"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Y-C-P-F-C-N-A-E-D-T-K-V-I-D-S-R-L-V-E-E-G-T-Q-V-R-R-R-R-E-C-L-K-C-Q-E-R-F-T-T-F-E-T-A-E-L-N-L-P-R-I-I-K-R-D-G-R-R-S-A-F-D-E-E-K-L-R-A-G-L-L-K-A-L-E-K-R-P-I-S-T-E-Q-I-E-T-A-V-Q-R-I-I-H-K-L-R-A-R-G-E-C-E-V-S-S-Q-W-L-G-E-L-V-M-D-E-L-R-A-L-D-E-V-A-Y-V-R-F-A-S-V-Y-R-S-F-Q-D-I-N-A-F-R-D-E-I-R-R-L-Q-K-Q-Q-K-K-S-H-D-K"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-I-N-K-T-R-H-N-A-R-R-Y-A-L-Q-A-L-Y-Q-W-F-F-C-E-T-K-P-D-A-L-I-S-Q-F-M-E-E-H-D-L-S-D-T-D-V-A-Y-F-K-E-V-V-T-G-T-I-Q-H-V-A-I-I-D-E-L-M-T-A-H-L-D-R-K-I-S-A-L-N-P-V-E-L-S-V-L-R-L-S-I-Y-E-L-L-H-R-K-E-V-P-Y-K-V-V-I-D-E-A-L-E-L-V-K-E-F-G-A-E-A-G-H-K-Y-V-N-A-I-L-D-V-L-S-S-E-I-R-K-G-V"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-D-I-I-N-D-S-K-S-R-M-E-K-S-L-G-S-L-K-T-E-L-A-K-L-R-T-C-R-A-H-P-S-L-L-E-H-I-K-V-D-Y-Y-N-V-E-T-P-L-S-Q-V-A-S-I-A-I-E-N-P-R-T-L-S-I-T-P-W-E-K-N-M-V-G-P-I-E-K-A-I-Q-K-A-D-L-G-L-N-P-A-T-V-G-M-V-I-R-V-P-L-P-P-L-T-E-E-R-R-K-E-L-A-R-V-V-R-E-E-A-E-H-A-R-V-A-I-R-N-I-R-R-E-A-N-N-D-L-K-E-L-M-K-E-K-E-I-S-E-D-E-E-R-R-A-Q-T-A-I-Q-K-L-T-D-A-Q-I-A-E-V-D-K-M-A-S-Q-K-E-A-D-L-M-A-V"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-R-S-K-R-T-R-V-N-N-Q-I-R-V-P-E-V-R-L-I-D-E-K-G-E-Q-V-G-V-V-R-T-D-R-A-L-T-M-A-E-E-A-G-L-D-L-V-E-I-S-P-T-A-K-P-P-V-C-R-I-M-N-F-G-K-Y-Q-F-E-Q-S-K-R-K-A-A-Q-K-K-K-Q-R-L-V-H-L-K-E-V-K-F-R-P-G-T-D-V-G-D-Y-Q-V-K-L-R-K-I-A-T-F-L-D-R-G-D-K-V-K-V-S-L-R-F-R-G-R-E-M-Q-H-R-E-L-G-L-E-L-L-G-R-V-K-R-D-L-G-N-I-V-V-E-Q-E-P-R-L-E-G-R-Q-M-T-M-V-V-M-K-A-K-G-E-G-N-K-T-K-R-E-D-H-A-E-I-K-D"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-R-A-R-H-K-K-V-L-T-K-A-K-G-Y-Y-G-A-R-S-R-V-F-R-V-A-K-Q-A-V-I-K-A-A-Q-Y-A-Y-R-D-R-K-Q-R-K-R-Q-F-R-A-L-W-I-V-R-I-N-A-A-A-R-E-H-G-L-S-Y-S-R-L-I-N-G-L-M-K-A-S-V-A-I-D-R-K-N-L-A-E-L-A-V-Y-D-K-A-A-F-G-K-L-A-E-K-A-K-Q-A-L-G-G"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-D-L-S-E-H-L-F-N-V-V-G-L-N-K-R-E-A-K-D-L-V-E-L-F-F-K-E-I-S-L-S-L-E-R-G-E-P-V-K-L-S-G-F-G-N-F-N-L-R-D-K-G-E-R-P-G-R-N-P-K-T-G-E-E-I-P-I-T-A-R-R-V-V-T-F-R-A-G-H-K-L-K-S-R-V-E-K-N-V-K-P-K-E-E-G-E-S"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-N-K-Q-I-S-K-K-P-A-Q-R-T-I-A-L-N-K-K-A-L-H-D-Y-Y-V-E-Q-R-F-E-A-G-L-V-L-E-G-W-E-V-K-S-I-R-A-G-R-V-Q-L-R-D-S-Y-V-V-F-K-G-G-E-A-W-L-I-G-A-H-L-S-P-L-P-N-V-A-E-Y-M-K-A-D-P-Q-R-S-R-K-L-L-L-N-K-R-E-I-G-K-L-F-G-A-V-Q-K-Q-G-L-T-V-V-P-L-D-L-H-W-H-K-N-H-V-K-V-E-I-V-L-A-K-G-K-K-T-H-D-K-R-E-T-I-K-R-R-E-W-E-R-E-K-H-R-V-L-K-S-H-G"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-D-F-S-D-D-N-L-I-W-L-D-L-E-M-T-G-L-D-P-E-R-D-R-I-I-E-I-A-T-I-V-T-N-S-H-L-D-I-L-A-E-G-P-A-F-A-I-H-Q-P-D-K-L-L-T-A-M-D-N-W-N-T-S-H-H-T-A-S-G-L-L-E-R-V-K-N-S-S-V-D-E-V-E-A-E-T-L-T-L-A-F-L-E-K-Y-V-S-A-G-K-S-P-L-C-G-N-S-V-C-Q-D-R-R-F-L-S-R-Y-M-P-R-L-N-Q-F-F-H-Y-R-H-L-D-V-T-T-L-K-I-L-A-Q-R-W-A-P-Q-I-A-A-A-H-I-K-E-S-Q-H-L-A-L-Q-D-I-R-D-S-I-E-E-L-R-Y-Y-R-A-H-L-L-N-L-S-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-S-I-E-M-Q-G-T-V-V-D-S-L-P-N-T-T-F-R-V-K-L-E-N-G-H-V-V-T-A-H-I-S-G-R-M-R-K-H-Y-I-R-I-L-T-G-D-A-V-T-V-E-L-T-P-Y-D-L-T-R-G-R-I-V-Y-R-E-A-G-K-K-P-P-T-S-K-A-E-E"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-I-G-E-S-V-I-I-G-D-D-I-K-I-T-V-L-G-V-K-G-N-Q-V-R-L-G-I-D-A-P-K-D-I-S-V-H-R-E-E-I-Y-E-R-I-Q-Q-E-K-L-A-Q-S-E-D-Q-G-E-K-T-D-E-F-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-R-I-I-C-Q-K-L-G-K-E-A-D-A-L-N-Y-S-P-Y-P-G-E-L-G-E-R-I-Y-N-H-I-S-E-Q-A-W-Q-A-W-L-S-H-Q-T-M-L-I-N-E-Y-R-L-S-L-I-D-P-K-A-R-Q-F-L-E-Q-E-M-I-N-F-L-F-G-T-G-S-E-K-P-A-G-Y-T-S-E-K-E"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-F-L-F-D-Y-F-P-I-I-C-F-F-V-A-Y-K-F-W-G-I-Y-I-A-T-A-A-A-M-V-V-S-A-L-Q-V-A-I-Y-W-I-R-F-R-R-F-E-K-F-H-V-I-T-L-I-F-I-L-L-L-G-S-F-T-L-V-F-H-N-A-I-F-I-K-W-K-P-T-I-V-Y-W-I-F-A-I-V-L-F-G-S-H-F-F-G-K-H-T-L-V-H-R-M-L-K-E-K-I-E-L-P-A-K-T-W-S-R-L-N-L-S-W-A-L-F-F-L-I-L-G-V-L-N-L-F-V-V-Y-N-F-D-T-N-T-W-V-N-F-K-L-F-G-T-L-V-L-T-L-V-F-I-L-G-Q-A-F-Y-I-A-R-H-A-Q-N-L-K-M-N-S-R"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-E-N-I-H-P-P-Y-K-Q-I-K-V-T-C-S-C-G-N-T-F-M-T-G-S-T-L-D-R-E-L-H-L-E-I-C-S-A-C-H-P-F-Y-T-G-Q-Q-K-M-V-D-T-A-G-R-V-E-R-F-R-K-K-Y-A-K-R-R-A-A-N-A-S-P-E-D-E-K-K"} +{"text": "### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-M-V-S-R-L-L-K-N-Y-S-L-Y-F-A-W-L-T-A-L-I-A-T-L-G-S-L-Y-L-S-L-V-R-H-I-P-V-C-D-L-C-W-Y-Q-R-V-C-I-Y-P-L-T-I-L-L-G-I-A-A-Y-R-T-D-R-G-V-V-K-Y-A-L-P-L-V-V-L-G-F-L-F-S-V-Y-Q-Y-L-Q-Q-M-I-P-G-F-A-P-I-N-L-C-G-S-T-S-P-H-C-S-E-I-H-W-E-I-F-G-F-I-T-L-P-F-L-G-M-L-A-T-L-I-M-S-F-F-L-I-M-A-F-Y-S-L-D-K-R-L-A-N"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-N-E-P-L-A-S-K-K-I-R-W-K-C-R-R-G-M-L-E-L-D-I-L-L-E-R-F-Y-E-E-K-F-R-S-L-T-K-N-E-K-E-I-F-N-Q-L-L-D-Q-P-D-P-L-L-Y-D-W-L-L-G-H-V-T-P-E-S-S-E-F-K-K-I-I-R-K-I-Q-Q-L-S-S"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-I-L-Q-E-K-V-A-N-L-G-N-I-G-D-Q-V-V-V-K-P-G-Y-A-R-N-F-L-L-P-L-G-K-A-V-P-A-T-P-E-H-I-A-E-F-E-K-Q-R-A-E-L-E-K-A-A-A-E-L-L-A-K-A-K-A-R-A-K-K-L-E-D-K-S-F-K-I-T-A-N-A-S-D-E-G-R-L-F-G-S-I-G-P-R-E-I-A-Q-A-I-T-E-A-G-I-E-I-E-K-R-E-V-D-L-S-Q-G-P-I-R-Q-V-G-E-Y-E-V-P-L-R-L-H-T-D-V-S-V-N-V-K-I-E-V-A-P-E-N-S-N-S"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-F-R-R-K-K-F-C-A-F-D-A-K-N-L-Q-E-I-D-Y-K-D-V-N-T-L-K-D-Y-I-M-E-S-G-R-V-V-P-S-R-I-T-G-T-C-A-K-H-Q-R-Q-I-S-R-A-I-K-L-A-R-Y-L-A-L-L-P-Y-C-D-T-H-Q"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-I-L-V-H-P-D-Q-S-S-Q-V-P-A-M-V-E-R-Y-Q-S-M-I-K-E-K-D-G-K-V-H-R-L-E-D-W-G-R-R-Q-L-A-Y-S-I-D-K-V-H-K-A-H-Y-L-L-M-N-I-E-S-D-Q-G-V-I-S-E-L-E-N-A-F-R-Y-N-D-A-V-I-R-S-L-I-L-K-R-D-H-A-I-T-K-S-S-L-I-M-Q-G-A-E-K-G-K-S-S-R-K-E-K-V-A-A-E-A-E-A-S-E-E-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-A-S-A-E-T-A-K-I-V-K-E-Y-Q-L-G-K-D-D-T-G-S-P-E-V-Q-V-A-I-L-T-A-K-I-I-K-L-T-D-H-M-K-A-H-K-H-D-H-H-S-R-R-G-L-L-R-M-V-S-Q-R-R-K-L-L-N-F-L-K-R-N-D-L-Q-R-Y-L-K-L-I-E-R-L-G-L-R-S"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-I-G-G-K-F-N-L-G-S-L-M-K-N-A-K-K-I-Q-E-M-M-Q-K-A-Q-D-E-L-A-K-I-R-V-T-G-E-S-G-A-G-M-V-K-L-T-M-T-A-Q-H-E-V-V-E-M-N-L-D-D-E-L-L-K-E-S-K-E-V-I-E-D-L-I-K-A-A-L-N-D-A-N-Q-K-I-L-K-I-T-Q-E-K-M-M-S-A-G-S-L-F-G-G-N-E-S-D-N-E-E-T"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-M-Y-K-Q-I-S-H-L-E-A-W-E-L-V-K-K-R-D-I-V-I-A-D-V-R-D-Q-D-S-Y-E-E-E-H-I-A-N-A-L-H-L-S-M-A-K-L-Q-E-Y-S-E-K-A-D-K-E-K-P-V-L-V-Y-C-Y-H-G-I-S-S-Q-S-V-A-Q-H-L-V-E-Q-G-F-K-E-V-Y-S-L-I-G-G-F-E-T-W-K-A-H-H-P-T-S-D-A-N-K-N"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-S-I-D-V-Q-H-A-T-Q-F-E-D-L-P-S-L-S-N-I-E-Q-W-V-E-T-A-L-Q-F-I-V-T-D-K-N-K-S-A-L-T-I-R-F-I-D-K-E-E-S-T-E-L-N-E-H-Y-R-H-K-K-G-P-T-N-V-L-S-F-P-D-E-P-I-P-G-F-P-S-E-S-F-G-D-L-A-I-C-A-P-L-V-A-E-E-A-H-A-Q-H-K-T-T-E-A-H-F-A-H-L-I-T-H-G-F-L-H-L-L-G-Y-D-H-V-E-N-E-D-A-E-E-M-E-N-L-E-I-K-I-L-S-Q-L-G-F-E-N-P-Y-E-E"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-P-R-K-K-T-E-N-F-N-F-E-A-S-L-N-E-L-T-A-L-V-E-K-L-E-Q-G-D-L-T-L-E-E-S-L-Q-N-F-E-R-G-V-G-L-V-R-S-C-Q-Q-A-L-S-D-A-E-Q-K-V-K-V-L-I-N-Q-D-G-A-E-T-L-V-P-F-E-L-E-T-K-T-D"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-P-N-D-K-V-I-I-G-R-L-A-R-P-Y-G-L-R-G-W-I-K-V-V-S-F-T-H-P-I-D-N-L-L-N-H-P-T-W-Q-I-Q-H-N-N-E-W-Q-P-L-K-L-Q-A-G-K-L-H-E-P-F-L-V-V-K-L-E-N-I-D-D-P-E-T-A-K-H-Y-T-N-D-L-I-A-I-E-R-G-A-L-G-A-L-K-E-G-D-Y-Y-W-T-D-L-I-G-L-A-V-V-N-T-H-G-I-E-L-G-T-V-D-S-L-I-E-T-G-S-N-D-V-L-V-V-R-S-K-E-R-E-R-L-I-P-Y-T-S-Y-T-I-Q-S-I-D-L-E-K-K-I-I-V-V-E-W-D-A-D-F"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-N-I-I-Q-L-L-E-T-E-Q-T-Q-G-K-E-I-P-D-F-R-A-G-D-T-V-T-V-Q-V-K-V-K-E-G-N-R-E-R-L-Q-A-F-E-G-V-V-I-A-R-R-H-R-G-L-N-S-S-F-T-V-R-K-V-S-H-G-E-G-V-E-R-V-F-Q-L-Y-S-P-L-I-A-S-I-K-V-N-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-N-L-R-G-R-K-A-K-I-K-E-K-I"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-S-A-Q-A-K-K-R-A-R-Q-N-E-K-R-E-L-H-N-A-S-Q-R-S-A-V-R-T-A-V-K-K-I-L-K-S-L-Q-A-N-D-S-S-A-A-Q-S-A-Y-Q-H-A-V-Q-I-L-D-K-A-A-G-R-R-I-I-H-P-N-K-A-A-R-L-K-S-R-L-S-Q-K-I-K-N-L-S-S-S-Q"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-K-T-G-G-K-Q-Y-R-V-T-E-G-Q-M-L-K-V-E-K-L-A-Q-D-V-G-Q-S-V-K-F-D-D-V-L-M-V-A-A-G-D-E-L-H-I-G-T-P-S-V-K-D-A-A-V-T-A-E-V-V-D-Q-G-R-Q-A-K-I-E-I-I-K-F-K-R-R-K-H-H-M-K-R-Q-G-H-R-Q-D-F-T-A-V-K-I-T-E-I-A-L-G-K-A-K-K-E-V-K-T-D-G-A"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-C-L-E-H-V-E-N-R-F-D-L-V-L-K-A-A-K-R-A-H-I-L-E-L-G-G-A-E-P-M-V-P-R-D-N-D-K-P-A-V-L-A-L-R-E-I-A-A-G-Y-D-V-T-R-E-G-Q-E-Q-E-T-E-E-V-D-V-D-R-N-V-L-A-E-T-A-K-M-N-K-A-V-A-S-Q-K-E-S-E-V"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-R-G-V-N-K-V-I-L-I-G-N-L-G-Q-D-P-E-V-R-Y-T-P-N-G-N-A-V-A-N-V-T-L-A-T-S-T-T-W-R-D-K-Q-T-G-E-L-Q-E-R-T-E-W-H-R-I-A-F-F-N-R-L-A-E-I-V-G-E-Y-L-R-K-G-S-K-I-Y-I-E-G-S-L-R-T-R-K-W-Q-D-K-N-G-V-D-R-Y-T-T-E-I-I-A-N-E-M-H-M-L-D-N-R-G-G-G-N-S-G-N-Y-G-N-H-S-E-G-G-A-S-N-K-Q-S-A-P-T-S-S-Q-T-P-T-A-G-D-D-S-S-V-A-D-F-D-D-D-I-P-F"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-K-R-Y-R-K-V-T-E-G-I-A-H-I-K-A-T-F-N-N-T-M-I-S-V-S-D-P-Q-G-N-V-L-C-F-R-S-A-G-G-S-G-F-K-G-S-R-K-G-T-P-Y-G-A-Q-M-A-S-E-E-V-G-R-L-A-R-D-N-F-D-M-R-R-I-A-V-R-V-K-G-P-G-A-G-R-D-S-A-I-R-G-L-R-S-A-G-L-E-V-I-H-L-E-D-R-T-P-L-P-H-N-G-C-R-P-R-K-K-R-R-V"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-L-N-D-L-K-P-A-K-G-A-R-H-Q-K-L-R-V-G-R-G-I-G-S-G-K-G-K-T-A-G-R-G-H-K-G-Q-H-S-R-A-G-G-Y-H-K-V-G-F-E-G-G-Q-M-P-L-Q-R-R-V-P-K-F-G-F-T-S-R-K-E-L-I-S-A-E-V-R-L-G-E-L-N-K-I-S-G-D-V-V-D-L-A-S-L-K-A-A-N-I-I-S-R-Q-I-K-R-V-K-I-F-A-A-G-K-L-E-K-P-V-T-I-R-G-L-R-V-T-K-G-V-K-A-A-V-E-A-A-G-G-K-I-E"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-Q-E-A-G-I-G-T-T-T-D-G-I-Q-E-K-L-V-A-V-R-R-T-A-K-V-V-K-G-G-R-V-F-G-F-S-A-L-V-V-A-G-D-G-D-G-K-V-G-F-G-L-G-K-A-R-E-V-P-S-A-I-Q-K-A-T-E-N-A-R-R-N-M-I-S-V-P-L-Y-G-A-T-L-H-H-A-I-K-A-T-H-A-S-S-T-V-L-M-L-P-A-S-E-G-T-G-V-I-A-G-N-A-M-R-A-I-F-E-V-M-G-V-Q-N-V-L-A-K-C-I-G-S-S-N-P-I-N-V-V-R-A-T-F-K-G-L-K-Q-M-E-T-P-E-S-V-A-A-K-R-G-K-A-I-E-E-I-V-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-Q-E-K-R-I-R-R-A-R-R-T-R-A-K-I-K-E-L-G-A-V-R-L-C-V-H-R-S-L-N-H-I-Y-A-Q-L-I-S-P-R-D-S-K-V-L-V-C-A-S-T-L-E-K-E-V-R-S-Q-I-K-H-G-G-N-I-Q-A-A-T-A-I-G-K-L-I-A-Q-R-A-K-K-A-G-V-T-K-V-A-F-D-R-S-G-Y-K-Y-H-G-R-V-R-A-L-A-E-A-V-R-E-G-G-I-E-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-V-S-R-V-A-K-N-P-I-K-I-P-T-G-V-E-V-N-V-A-G-Q-Q-I-T-V-K-G-K-L-G-T-L-T-R-V-I-H-R-A-V-K-V-T-K-T-D-A-E-L-Q-T-I-C-A-N-D-S-P-G-S-N-A-L-A-G-T-A-R-A-V-L-A-N-M-V-Q-G-V-H-T-G-F-Q-R-K-L-V-M-V-G-V-G-Y-R-A-K-A-E-G-K-K-L-N-L-T-V-G-L-S-H-P-V-N-I-E-M-P-E-G-I-T-V-E-T-P-S-Q-T-E-I-I-V-K-G-A-D-K-Q-R-V-S-Q-V-A-A-N-I-R-E-I-R-P-P-E-P-Y-K-G-K-G-I-R-Y-D-N-E-R-V-I-L-K-E-A-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-M-Q-D-P-I-S-D-M-L-T-R-I-R-N-A-Q-A-V-R-K-K-E-V-V-M-P-R-S-K-L-K-M-S-I-A-N-V-L-K-E-E-G-Y-I-V-D-Y-R-E-E-G-D-L-T-K-A-Q-L-V-I-T-L-K-Y-H-E-G-E-S-V-I-S-E-I-R-R-V-S-S-P-A-L-Q-V-Y-K-S-K-D-E-L-P-K-V-K-N-G-L-G-I-A-I-I-S-T-S-K-G-V-M-S-D-R-Q-A-R-R-L-G-E-G-G-E-V-L-C-Y-V-S"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-V-E-L-Q-E-L-Y-K-K-T-I-T-P-A-L-Q-K-E-F-G-F-K-S-V-M-A-V-P-R-L-E-K-I-T-L-N-M-G-L-G-E-A-V-A-D-K-K-V-I-E-R-A-M-D-D-M-I-K-I-S-G-Q-K-P-L-I-T-Y-A-R-K-S-E-A-G-F-K-I-R-A-G-W-P-I-G-C-K-V-T-L-R-R-D-R-M-Y-E-F-L-K-R-L-I-S-I-A-I-P-R-I-R-D-F-R-G-L-S-P-K-S-F-D-G-R-G-N-Y-S-L-G-I-R-E-Q-I-V-F-P-E-I-Q-Y-D-K-V-D-A-I-R-G-M-D-I-T-I-T-T-T-A-R-T-D-E-E-G-R-A-L-L-K-A-F-G-F-P-L-K-D-E-S-R"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-I-K-K-I-K-K-D-D-T-V-I-V-I-T-G-R-D-K-G-R-Q-G-K-V-L-K-V-L-P-N-S-R-L-L-V-E-G-I-N-L-V-K-K-H-V-K-P-N-P-N-K-N-E-Q-G-G-I-L-E-R-E-L-S-I-H-V-S-N-V-A-I-Y-N-P-A-A-K-K-A-D-R-V-G-I-K-T-L-E-D-G-S-K-V-R-I-F-K-S-N-G-E-V-I-D-V"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-T-Q-S-I-V-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-N-I-G-D-V-I-K-V-S-I-K-E-A-I-P-R-G-K-V-K-K-G-D-V-M-H-A-V-V-V-R-T-R-K-G-V-R-R-N-D-G-S-L-I-R-F-D-N-N-A-V-V-L-L-N-N-Q-L-Q-L-V-G-T-R-V-F-G-P-V-V-R-E-L-R-T-D-K-F-M-K-I-I-S-L-A-L-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-N-K-N-E-K-M-V-R-S-L-M-G-T-V-V-S-N-K-M-N-D-T-V-V-V-R-V-E-R-R-V-K-H-P-K-Y-G-K-F-I-K-R-S-T-K-I-H-A-H-D-K-G-N-E-G-Q-I-G-D-I-V-T-I-R-E-C-R-P-I-S-K-T-K-S-W-T-L-V-K-I-N-E-R-A-E-K-V-E"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-S-N-R-K-Y-R-K-D-F-K-G-R-N-R-G-V-A-S-R-G-N-R-V-S-F-G-E-F-G-L-K-A-T-E-C-A-R-I-T-A-R-Q-L-E-A-A-R-R-T-I-A-R-H-I-K-R-G-G-K-I-T-I-R-I-F-P-D-K-P-I-T-K-K-P-L-E-V-R-Q-G-K-G-K-G-S-V-E-Y-W-V-A-L-V-Q-P-G-R-M-I-F-E-I-E-G-V-D-E-A-L-A-R-E-A-F-S-R-A-A-A-K-L-P-L-K-C-L-F-V-K-R-T-V-M"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-T-N-K-G-P-F-V-D-H-H-L-M-K-K-V-D-Q-A-Q-K-E-G-S-K-R-P-I-K-T-W-S-R-R-S-M-V-V-P-E-M-V-G-L-T-I-A-I-H-N-G-R-Q-H-V-P-V-Y-I-S-E-N-M-V-G-H-K-L-G-E-F-A-I-T-R-T-F-R-A-H-S-G-D-R-K-A-K-K-E-G-E-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-E-E-R-L-F-E-I-L-L-A-P-H-I-S-E-K-G-A-L-T-T-G-Q-Y-V-F-E-V-M-P-D-A-T-K-P-E-I-K-R-A-V-E-K-Q-F-N-V-T-V-K-S-V-R-T-C-N-V-K-G-K-T-T-R-F-R-Q-V-R-G-R-R-K-N-W-K-K-A-Y-V-M-L-A-P-G-S-E-I-D-I-A-A-G-E"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-D-N-Q-R-I-R-I-R-L-K-A-F-D-H-R-L-I-D-R-S-T-R-E-I-V-E-T-A-R-R-T-G-A-I-I-R-G-P-I-L-L-P-T-K-I-E-R-Y-T-V-L-I-S-P-N-I-D-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-L-V-D-I-S-E-P-T-D-K-T-V-D-A-L-M-K-L-D-L-A-A-G-V-D-V-Q-I-E-L-L-N-K-K-S-G-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-A-R-R-K-A-A-P-K-R-E-T-L-P-D-P-L-F-H-S-E-L-L-A-K-F-I-N-A-V-M-R-N-G-K-K-S-V-A-E-K-I-V-Y-G-A-L-D-V-V-A-K-R-V-Q-N-K-S-G-E-Q-G-D-G-D-G-E-S-G-G-K-A-G-G-I-K-K-R-S-L-G-D-I-R-T-D-E-N-A-R-A-L-A-L-E-T-F-K-G-A-L-D-K-V-M-P-N-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-I-R-M-A-R-R-Q-A-L-A-R-R-W-L-V-E-Y-A-N-K-R-N-E-K-T-M-V-L-R-L-A-H-E-I-L-D-A-V-E-G-R-G-G-A-I-K-K-R-E-D-V-H-R-M-A-K-A-N-Q-A-F-A-H-Y-K-W"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-E-Q-K-K-A-M-V-A-E-I-T-D-I-A-N-Q-A-V-S-A-V-A-A-D-Y-R-G-L-T-V-S-E-M-S-D-L-R-K-S-A-R-E-A-R-V-H-M-R-V-Y-R-N-T-L-A-R-R-A-F-K-E-T-T-Y-A-C-L-E-E-V-L-T-G-P-I-V-L-F-F-S-Q-E-E-P-G-A-A-A-R-L-I-E-K-F-I-K-E-H-E-R-L-E-V-K-G-L-A-L-G-G-E-L-L-P-A-E-K-L-K-A-V-A-R-L-P-S-R-E-E-A-L-S-Q-L-A-A-V-L-L-A-P-V-T-K-L-V-R-T-L-N-E-P-I-A-Q-V-A-R-V-M-A-A-V-R-D-Q-K-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-T-G-Y-I-R-L-Q-I-K-A-G-E-A-N-P-S-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-R-E-F-C-E-S-F-N-T-A-T-K-N-I-E-K-G-L-P-T-P-V-I-I-T-V-Y-A-D-R-T-F-S-F-I-T-K-T-P-P-A-S-V-L-L-K-K-F-V-L-K-G-K-S-G-S-A-R-P-N-T-E-K-V-G-K-A-T-R-Q-Q-L-E-E-I-A-K-M-K-T-P-D-L-T-A-A-D-L-E-A-A-I-R-T-I-A-G-T-A-R-S-M-G-I-D-V-E-G-V-E"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-N-T-A-T-R-V-I-V-A-Q-N-V-R-T-R-N-R-T-F-Q-I-T-K-Q-G-V-V-I-V-A-L-V-I-A-L-L-C-S-A-F-G-V-V-Y-F-K-D-L-N-R-R-L-F-I-Q-Y-Q-T-L-Q-R-E-K-A-E-E-L-I-Q-W-G-K-L-L-L-E-Q-T-T-W-S-T-Q-S-R-V-Q-R-I-A-E-Q-Q-L-G-M-Q-L-P-S-A-K-E-V-I-L-V-N-A-D-A-M-I-E"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-K-K-Q-L-F-W-A-P-Q-N-E-I-P-S-T-L-W-T-A-N-E-R-S-W-L-T-H-P-G-S-L-T-Q-R-L-R-K-T-T-D-G-Q-I-Q-H-H-L-L-R-E-V-F-D-A-P-V-D-E-E-T-Q-L-L-G-I-S-Q-P-E-L-A-L-I-R-E-I-E-W-R-Y-F-E-S-L-W-V-A-G-R-V-V-I-P-K-K-T-L-E-R-E-G-S-P-L-N-H-I-G-E-R-S-L-G-D-I-L-F-A-N-A-K-F-T-R-G-D-L-E-F-R-Q-I-T-A-D-H-P-Y-Y-F-Y-V-K-E-I-A-N-G-S-C-I-W-A-R-R-S-L-F-Y-F-E-R-D-P-L-L-V-S-E-I-F-S-P-A-L-F-L-E-S-S-V-S-N-D"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-V-L-T-R-T-N-G-Q-A-I-K-I-G-N-E-G-E-I-T-V-T-V-L-E-V-R-G-N-Q-V-R-M-G-I-D-A-P-K-H-I-A-V-H-R-E-E-I-Y-Q-R-I-Q-E-E-K-P-K-A-P-P-I-L-E-E-V-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-D-K-K-V-V-G-V-I-K-L-Q-I-Q-A-G-A-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-Y-N-A-A-T-E-S-Q-K-G-N-V-I-P-V-E-I-S-V-Y-E-D-R-S-F-T-F-V-L-K-T-P-P-V-V-E-L-I-K-K-A-A-R-I-S-K-G-S-P-T-P-H-N-L-K-V-A-Q-I-T-P-E-Q-V-K-S-I-A-E-A-K-M-V-D-L-N-A-N-D-I-D-A-A-S-K-I-V-R-G-T-A-R-S-M-G-V-T-V-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-T-K-Q-E-T-V-K-H-L-V-G-V-L-S-D-A-Q-A-I-V-F-T-E-Y-R-G-L-S-A-A-Q-L-R-A-L-R-I-L-L-R-G-D-A-S-Y-L-I-A-K-N-T-L-A-R-I-A-A-Q-Q-V-G-F-N-D-F-A-E-F-L-R-G-P-T-A-I-V-A-V-D-G-D-I-V-S-V-A-K-S-L-R-K-F-A-E-T-D-G-L-L-K-I-K-G-C-F-V-D-G-Q-V-F-G-S-E-H-V-K-R-L-A-E-L-E-S-R-E-V-I-L-A-K-I-A-S-V-T-K-G-A-L-S-S-A-L-G-L-V-S-A-P-L-S-S-A-A-R-V-F-V-A-M-K-N-T-F"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-K-E-D-G-M-A-K-I-T-T-D-E-L-I-E-S-F-K-E-M-T-L-I-E-L-S-E-F-V-S-K-F-E-E-V-F-K-V-T-A-A-A-P-V-A-A-A-A-A-P-V-E-P-A-A-E-A-A-P-E-K-T-T-F-D-V-I-L-E-A-A-G-D-K-K-I-Q-V-I-K-E-V-R-T-I-T-G-L-G-L-G-E-A-K-A-L-V-D-G-V-P-S-K-V-L-E-G-A-N-K-D-A-A-D-A-A-K-A-Q-L-E-A-A-G-A-Q-V-S-V-K"} +{"text": "### FUNCTION Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis ### SEQUENCE -M-F-V-T-F-E-G-I-D-G-S-G-K-T-A-Q-L-T-A-A-G-E-F-L-K-A-S-G-K-Q-V-V-L-T-R-E-P-G-T-I-S-C-I-R-D-Y-V-L-A-S-D-M-D-I-R-T-E-A-L-L-Y-S-A-D-R-A-E-N-I-A-K-N-V-I-P-A-L-N-A-G-K-V-V-L-Q-D-R-Y-L-D-S-F-L-A-Y-Q-L-A-D-N-K-L-V-E-T-D-I-M-R-L-F-E-F-S-S-Q-G-L-R-P-D-L-T-L-L-F-D-L-T-P-A-C-A-Q-E-R-L-E-N-R-D-R-I-E-R-K-P-I-D-F-H-S-K-V-R-N-I-Y-L-K-L-S-A-D-N-T-D-R-I-R-V-I-D-A-S-Q-S-F-S-K-I-H-Q-Q-V-I-Y-H-I-E-R-K-L-G-G-T-H-S-A"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-G-K-D-R-N-L-S-L-N-S-P-E-S-I-Q-S-V-I-G-D-T-D-I-K-I-A-V-I-A-A-M-W-H-E-K-I-V-R-G-L-I-D-G-A-T-R-E-I-V-S-S-G-S-H-A-E-L-F-R-V-P-G-S-V-E-L-V-L-A-C-K-K-L-L-K-T-F-D-A-A-V-A-L-G-V-I-L-R-G-E-T-D-H-N-T-H-I-A-R-L-V-L-S-G-I-T-D-V-M-L-A-L-E-K-P-I-G-I-G-V-L-T-I-D-T-E-Q-Q-G-L-D-R-S-S-G-D-Y-N-A-G-V-N-A-A-R-A-V-I-R-M-V-R-L-F-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-V-R-R-E-I-P-E-D-P-V-Y-S-S-R-V-V-S-Q-L-I-G-R-V-L-L-S-G-K-K-S-L-A-Q-R-I-V-Y-S-A-L-D-K-V-S-M-K-A-S-E-D-P-V-S-V-L-R-K-A-L-D-N-V-R-P-S-L-E-V-R-S-R-R-V-G-G-S-T-Y-Q-V-P-V-P-V-R-S-H-R-A-D-A-L-A-I-R-W-L-T-V-Y-S-R-A-R-R-E-K-S-M-V-D-R-L-A-S-E-I-L-D-A-S-N-G-V-G-A-T-V-K-C-K-E-D-T-H-R-M-A-E-S-N-R-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-V-Y-P-V-V-E-A-E-S-R-V-G-F-G-K-G-F-A-R-R-A-R-A-A-G-K-I-P-A-V-A-Y-G-L-K-R-A-P-E-H-V-L-L-P-A-A-Q-M-S-L-I-M-R-R-A-N-A-L-L-Q-L-K-I-D-A-R-E-S-L-V-L-I-K-Q-V-Q-R-D-R-I-R-N-I-I-E-H-L-D-M-L-F-V-N-E-D-D-A-V-T-I-R-V-P-L-R-F-V-G-Q-S-Y-A-G-T-V-T-S-V-E-N-Y-S-V-A-V-T-L-Q-V-S-Q-I-P-E-A-L-V-V-D-V-S-G-L-Q-A-G-R-R-I-F-A-S-D-I-A-L-P-D-G-A-L-L-V-S-P-P-R-L-L-I-A-K-V-D-P-V-R-R-A-T-Q-E-S-P-P-D"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-C-V-Y-I-V-A-G-L-G-N-P-G-P-S-Y-D-K-T-R-H-N-V-G-Q-M-V-L-D-I-L-S-G-G-A-R-F-R-R-H-K-T-N-N-F-Y-L-S-L-G-D-I-L-L-V-K-P-D-A-Y-M-N-L-S-G-P-V-I-A-S-L-M-K-F-H-S-V-S-D-L-L-V-L-H-D-D-I-D-L-P-L-G-T-L-R-F-K-Q-G-G-G-T-A-G-H-R-G-L-R-S-I-S-D-C-L-G-S-D-Y-A-R-L-R-V-G-I-G-R-P-E-N-N-Q-S-I-E-D-F-V-L-S-N-F-S-P-V-Q-T-D-I-I-S-R-T-I-Q-L-A-A-E-A-V-L-H-L-R-D-N-G-F-V-G-V-K-Q-F-I-A-Q-T-K-L-P-S-R-T"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-E-E-Q-K-I-R-I-R-L-K-S-Y-S-H-E-I-I-D-V-S-A-K-K-I-V-D-T-V-T-R-A-G-A-T-I-V-G-P-V-P-L-P-T-K-K-S-V-V-C-V-I-R-S-P-H-R-H-K-D-S-R-E-H-F-E-M-R-T-H-K-R-L-I-N-V-V-D-L-T-P-R-A-V-D-A-L-M-R-L-D-L-S-S-E-V-N-V-E-I-K-L"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-V-D-M-H-L-L-K-K-V-R-A-G-N-E-S-K-D-R-N-M-I-K-T-W-S-R-R-S-M-I-I-P-E-M-L-G-H-T-I-A-V-H-D-G-R-R-H-I-P-V-F-I-T-E-S-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-V-K-D-D-R-K-A-R-R-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-E-E-K-D-T-P-L-E-A-F-A-S-L-K-H-S-G-V-T-P-Q-K-V-R-R-I-V-D-L-I-R-G-R-S-V-D-E-A-L-A-I-L-R-F-S-P-H-S-A-S-G-I-L-Y-K-L-I-V-S-A-Q-A-N-Y-A-N-L-L-G-R-D-D-D-L-F-V-S-S-V-Y-V-D-E-G-K-T-Y-K-R-G-R-P-R-A-R-G-S-S-S-R-I-L-K-R-G-S-H-V-T-V-T-L-S-K-E-V-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-M-L-I-P-K-K-V-K-F-R-K-Q-H-R-P-N-R-K-G-M-S-G-C-G-T-R-I-V-F-G-D-Y-G-I-Q-A-L-S-R-A-Y-V-T-N-R-Q-V-E-S-A-R-I-A-M-T-R-H-I-R-R-G-G-R-V-W-I-N-I-Y-P-D-R-P-L-T-K-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-Y-W-V-A-N-I-R-P-G-R-I-M-F-E-V-S-G-V-S-E-S-L-A-K-E-A-L-M-R-A-I-H-K-L-P-L-R-A-R-I-V-E-R-Q-E-F-D-D-A-G-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-Q-Q-R-G-Y-R-K-S-R-R-G-Y-V-T-S-N-S-M-D-K-T-I-V-V-K-I-E-D-R-V-K-H-A-L-Y-G-K-V-I-R-K-T-S-K-V-K-A-H-D-Q-G-S-I-A-G-V-G-D-L-V-L-I-S-E-T-R-P-I-S-A-T-K-R-W-R-L-V-Q-I-L-E-K-A-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-T-G-A-K-S-L-S-V-I-R-V-L-G-G-S-N-R-R-F-G-S-L-G-D-V-V-V-A-S-V-K-D-A-V-P-G-S-S-A-V-K-K-G-D-V-V-K-A-V-I-V-R-S-T-K-E-V-R-R-T-D-G-S-Y-I-R-F-D-D-N-A-A-V-I-L-R-P-D-N-D-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-R-K-F-T-R-I-I-S-L-A-P-E-V-V"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-V-K-I-R-K-G-D-L-V-Q-V-I-T-G-S-K-T-G-G-K-K-G-K-Q-G-R-V-L-A-V-S-G-D-R-V-W-V-E-G-V-N-L-T-T-R-H-R-K-R-V-T-N-D-K-G-T-S-S-G-G-L-E-K-R-E-S-P-M-H-I-S-N-V-A-L-V-D-P-E-T-G-A-P-T-K-V-G-F-L-V-K-T-S-G-D-K-T-V-R-V-R-F-A-K-K-S-G-K-E-L-T"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-C-Y-T-P-R-L-L-T-R-Y-R-E-E-I-V-P-V-L-M-S-R-F-D-I-N-N-V-H-Q-V-P-S-I-T-K-I-V-V-N-S-G-V-G-D-A-A-R-D-S-K-I-I-E-G-A-V-S-D-I-T-L-I-T-G-Q-K-P-R-I-N-R-A-K-Q-S-I-A-K-F-K-L-R-E-G-Q-A-V-G-V-T-A-T-L-R-G-R-R-M-W-E-F-L-D-R-L-L-T-L-A-L-P-R-I-R-D-F-R-G-I-S-D-K-Q-F-D-G-H-G-N-Y-T-F-G-L-S-E-Q-G-I-F-H-E-I-D-Q-D-K-I-D-R-V-R-G-M-D-I-T-V-V-T-T-S-S-S-D-D-M-A-R-A-L-L-G-E-L-G-F-P-F-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-L-S-D-M-F-S-R-I-R-N-A-N-Q-V-L-H-K-K-V-T-V-P-S-S-R-L-K-V-S-I-A-D-L-L-K-R-E-G-Y-I-L-D-Y-S-V-I-D-E-H-P-G-Q-L-L-V-I-E-L-K-Y-G-P-D-K-S-R-A-L-V-G-L-K-R-V-S-K-P-G-L-R-V-Y-A-K-S-S-N-L-P-E-V-F-G-G-L-G-I-A-I-L-S-T-S-S-G-L-L-T-C-S-Q-A-R-K-K-G-V-G-G-E-V-L-A-Y-A-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-L-P-I-E-I-P-V-G-V-E-V-C-V-N-G-R-T-V-S-I-T-G-P-K-G-S-L-Y-L-D-I-A-E-Q-I-G-V-S-V-S-D-G-K-V-L-V-S-R-S-D-D-S-R-T-A-R-A-L-H-G-L-T-R-A-L-I-A-N-N-V-H-G-V-L-H-G-Y-T-K-T-L-E-I-V-G-T-G-Y-R-V-S-K-K-G-E-N-L-E-L-A-L-G-F-S-H-P-V-F-V-D-P-V-P-G-V-S-F-G-V-E-G-N-S-K-I-I-V-S-G-I-D-K-Q-A-V-G-E-A-A-A-S-I-R-K-L-S-K-P-E-P-Y-K-G-K-G-I-R-Y-S-D-E-I-V-R-R-K-V-G-K-A-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-L-T-S-R-A-S-A-R-K-R-R-H-V-R-L-R-K-K-I-S-G-T-C-D-R-P-R-L-S-V-T-R-S-N-R-H-V-F-V-Q-A-V-D-D-I-S-G-K-T-L-V-S-A-S-T-M-E-K-D-I-R-A-L-E-L-G-K-T-E-R-A-L-A-V-G-K-L-V-A-Q-R-A-L-A-V-G-V-K-S-A-V-F-D-R-G-G-C-K-Y-T-G-R-V-A-A-V-A-E-G-A-R-E-A-G-L-Q-T"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-I-K-L-H-H-L-R-P-A-P-G-S-R-R-A-R-V-R-V-G-R-G-E-G-S-K-G-K-T-A-G-R-G-T-K-G-T-K-A-R-A-P-V-R-P-G-F-A-G-G-Q-I-P-L-H-M-S-I-P-K-L-K-G-F-K-N-H-K-K-V-E-Y-S-V-I-S-I-K-R-L-C-E-A-Y-P-S-G-G-V-V-T-R-D-N-V-M-S-V-I-G-K-K-R-G-F-V-K-L-L-S-D-G-E-V-T-V-K-F-D-I-T-V-D-K-A-S-A-A-A-V-E-K-I-T-S-A-A-G-T-V-T-Q-A-R"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-K-D-G-V-I-E-L-E-G-S-V-L-E-A-L-P-N-A-T-F-R-V-E-L-S-N-G-H-K-V-L-A-H-I-S-G-R-M-R-Q-H-Y-I-R-I-L-P-E-D-R-V-V-V-E-L-S-P-Y-D-L-A-R-G-R-I-V-Y-R-Y-K"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-G-G-L-K-K-A-M-V-Y-L-G-L-A-E-D-N-Q-E-L-H-S-A-P-S-G-M-S-H-L-R-R-V-P-H-P-K-Q-Q-M-S-E-I-F-T-F-H-P-K-K-Y-S-E-V-S-G-I-V-E-R-F-R-Q-N-I-P-V-I-I-D-M-S-Q-L-S-D-T-D-A-R-R-M-I-D-F-A-S-G-L-S-Q-G-L-V-G-K-I-E-R-V-V-G-K-V-F-L-L-S-P-E-H-I-S-I-S-T-E-S-K-K-E-E"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-V-E-V-L-F-K-G-G-Y-T-P-Q-R-A-F-D-G-D-A-G-F-D-L-Q-S-S-H-T-A-V-I-Q-P-R-C-R-Q-V-V-K-T-G-I-A-I-A-L-P-D-G-Y-A-G-F-I-M-P-R-S-G-L-A-S-E-N-G-I-T-L-V-N-S-P-G-V-I-D-A-G-Y-R-G-E-I-S-V-V-L-I-N-T-D-L-H-Q-A-F-H-I-S-Q-G-D-R-I-A-Q-L-V-I-M-P-V-C-H-A-S-F-I-E-V-D-T-L-P-G-S-A-R-G-I-S-A-F-G-S-S-G-R-H-D-T-R-G"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-E-T-K-Q-T-V-F-D-R-L-L-Q-E-R-I-V-W-L-G-E-A-I-D-D-K-L-A-N-E-I-C-A-K-I-L-L-L-N-A-D-D-P-K-E-D-I-F-L-Y-I-N-S-P-G-G-S-I-T-A-G-M-A-I-Y-D-T-M-Q-F-V-S-N-D-I-V-T-V-G-I-G-M-A-A-S-M-G-Q-V-L-L-T-S-G-T-Q-N-K-R-Y-I-M-P-N-A-R-V-L-L-H-Q-P-L-A-G-F-G-G-T-A-S-D-I-Q-T-Q-A-K-L-I-L-D-M-K-Y-R-L-S-Q-I-T-A-S-R-T-G-K-T-V-E-Q-I-M-E-D-G-D-R-D-H-W-F-T-A-E-E-A-L-E-Y-G-F-V-D-H-I-R-T-E"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-V-K-A-S-G-F-Q-R-L-V-E-V-G-S-V-I-S-I-D-P-T-N-V-D-S-G-G-F-V-H-F-P-V-L-L-L-V-D-G-A-E-V-V-S-D-P-D-K-L-R-L-A-R-V-S-A-K-F-L-R-K-L-R-G-P-K-V-R-I-H-K-F-K-N-K-T-G-Y-H-K-R-Q-G-H-R-Q-G-V-Y-V-F-S-V-T-S-I-E-R-G-D"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-G-G-T-F-D-P-I-H-H-G-H-L-V-V-A-S-E-V-A-S-R-F-C-L-D-E-V-I-F-V-P-T-G-R-P-P-H-K-K-E-V-S-D-P-W-H-R-Y-L-M-A-V-I-A-T-A-S-N-Q-R-F-S-V-S-K-I-D-I-E-R-T-G-P-T-F-T-V-D-T-L-R-E-L-R-E-Q-L-P-S-S-D-L-F-F-I-T-G-T-D-A-L-A-R-I-F-S-W-K-D-A-D-T-L-W-S-L-A-H-F-V-A-V-S-R-P-G-H-E-V-V-D-I-P-N-D-R-I-S-F-L-E-V-P-A-M-A-I-S-S-S-N-C-R-E-R-V-R-S-G-L-P-I-W-Y-L-V-P-E-G-V-V-Q-Y-I-A-K-H-G-L-Y-R-S-L-Y-G"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-H-A-L-D-A-L-D-A-L-S-I-K-A-D-I-P-D-F-S-P-G-D-T-V-R-V-Y-V-N-I-T-E-G-D-R-S-R-V-Q-V-F-Q-G-V-V-I-A-R-R-G-F-G-V-R-Q-T-F-T-V-R-K-I-S-F-Q-V-G-V-E-R-I-F-P-L-H-S-P-S-I-N-R-I-E-V-V-T-K-G-S-V-R-R-A-K-L-Y-Y-I-R-K-L-R-G-K-K-A-K-V-K-Q-K-R-E-L"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-G-I-M-C-S-G-D-V-S-E-R-M-N-K-T-I-E-L-L-K-E-Q-F-L-S-I-H-S-G-R-V-N-S-G-Q-F-E-K-V-M-V-D-C-E-G-A-S-V-P-L-V-S-L-A-S-I-R-V-L-N-A-N-T-I-V-V-T-P-Y-D-S-A-L-L-S-Q-I-D-R-A-L-R-N-V-P-N-I-G-T-P-G-N-D-G-E-C-I-K-I-V-M-P-Q-L-T-E-A-R-R-H-E-Y-V-K-Q-A-R-V-K-A-E-E-A-R-V-S-A-R-N-I-R-R-K-A-R-A-S-L-D-A-M-G-L-A-K-D-E-I-V-R-R-E-K-E-L-D-K-L-T-K-D-V-I-S-V-V-D-D-L-L-R-H-K-E-S-E-L-L-R-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-F-A-Q-P-H-N-P-L-L-P-S-V-P-D-I-V-F-S-A-I-V-L-A-I-V-L-P-F-F-W-W-F-V-I-P-R-I-S-K-L-L-S-D-R-S-S-L-I-E-G-K-I-S-E-A-A-S-A-H-A-R-A-L-E-T-L-E-L-R-K-Q-Q-L-D-E-A-K-S-E-A-S-Q-I-R-Q-E-A-R-D-D-A-Q-L-I-L-Q-Q-A-R-E-T-A-D-E-T-A-E-R-V-M-L-H-A-R-E-Q-I-Q-A-E-K-A-A-A-L-L-S-L-R-S-E-I-A-T-L-A-L-A-A-A-G-K-A-V-S-E-K-L-D-D-D-K-K-S-R-E-L-V-S-A-S-I-A-K-M-A-E-D-A-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-R-K-L-D-M-D-K-G-A-I-I-S-E-Y-G-L-S-K-G-D-T-G-S-P-E-V-Q-I-A-L-L-T-A-R-I-A-R-L-T-Q-H-L-K-E-H-S-F-D-H-H-S-R-R-G-L-M-L-M-V-G-R-R-R-R-L-L-S-Y-L-H-G-V-D-V-S-R-Y-R-A-I-L-S-N-L-G-L-R-R"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-C-V-A-P-T-P-S-H-L-V-W-V-D-C-E-M-T-G-L-N-P-E-R-D-E-L-L-E-V-A-V-V-V-T-D-K-D-L-L-P-L-D-E-G-V-N-V-V-V-S-P-S-S-E-A-L-G-A-M-D-N-Y-V-A-R-M-H-R-V-S-G-L-L-D-E-L-S-N-G-V-P-V-S-E-A-Q-A-M-V-K-E-Y-I-T-K-H-V-K-T-G-G-I-M-S-G-N-S-I-A-T-D-R-L-F-I-T-R-Y-M-P-D-V-H-A-I-L-H-Y-R-M-I-D-V-S-S-I-K-E-L-A-V-R-W-A-P-E-I-Y-S-G-A-P-N-K-K-G-G-H-R-A-M-A-D-V-L-E-S-I-A-E-L-A-Y-Y-R-E-H-F-L-T-G-T-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-V-K-S-V-A-D-R-F-F-L-G-L-D-F-G-S-T-R-I-G-V-A-R-N-C-G-S-L-A-V-P-V-G-V-L-P-R-A-S-C-A-E-I-L-G-Y-I-S-R-Y-S-I-D-E-V-V-I-G-L-P-L-T-L-A-G-K-E-K-Q-S-A-R-L-A-K-E-F-S-R-F-L-V-S-S-G-V-Q-V-R-F-F-D-E-R-F-T-T-V-I-A-T-Q-K-F-Y-S-L-G-K-G-V-K-Q-I-R-K-C-V-D-A-A-A-A-T-V-M-L-Q-L-F-L-D-M-E-V-K-V-D-P-L-E-R-K-P"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-G-L-L-Y-L-Q-N-S-S-G-Y-N-D-C-Y-F-K-T-E-S-L-V-D-F-L-Y-R-T-L-F-I-D-K-G-S-Y-L-G-V-S-F-I-T-A-A-E-M-R-D-L-K-I-K-H-F-G-V-N-E-D-S-D-V-L-S-F-P-I-D-E-I-A-P-G-S-E-N-S-L-V-Y-G-V-L-G-D-I-V-V-C-P-E-T-V-M-R-Q-A-V-R-H-P-F-E-H-E-I-Y-L-L-V-V-H-G-F-L-H-L-L-G-F-D-H-S-D-A-P-S-K-K-E-M-F-S-L-Q-A-K-L-I-E-D-F-F-A-L-E-N-L-G-T-P-S-E-E-I-T-I-T-P-D-L-R-P-S-L-G-R-I"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-I-K-R-N-R-T-N-E-N-N-R-L-R-N-K-A-V-K-S-E-L-K-T-L-I-R-L-V-K-R-A-A-R-D-N-D-L-P-R-A-E-D-A-L-R-R-A-S-L-K-L-D-R-A-V-S-K-G-V-I-H-P-N-Q-A-A-N-R-K-S-G-I-A-K-L-V-V-A-T-R-L-R-N-S-T-A-G-E"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-V-A-R-S-V-N-A-R-K-K-R-R-S-I-L-A-A-A-K-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-V-L-R-S-L-V-Y-A-Y-R-D-R-R-K-R-K-S-N-F-R-K-L-W-I-I-R-I-N-A-A-A-R-M-E-G-V-T-Y-N-R-F-L-Q-G-L-K-L-A-N-I-E-L-D-R-R-S-L-A-H-L-A-V-H-N-P-D-T-F-S-A-L-V-G-V-A-K-D-S-L-K-N-A-P-D-P-V-A-A-A-R-L-R-G-T-S-S-R-T"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-G-E-S-I-T-A-P-E-V-R-L-I-N-S-D-G-G-P-L-G-V-V-S-R-S-V-A-L-R-L-A-G-E-V-G-L-D-L-V-E-V-S-P-F-S-K-P-P-V-V-K-I-M-D-Y-G-K-F-R-Y-E-A-S-Q-K-A-K-E-A-R-R-R-Q-S-G-V-S-V-K-E-V-R-F-R-L-K-I-C-D-N-D-Y-D-V-K-L-R-K-A-I-S-F-L-Q-A-G-D-K-V-K-V-M-I-L-F-R-G-R-E-Q-S-R-P-E-L-G-V-K-L-L-K-K-F-A-D-D-I-S-E-F-G-S-A-D-S-L-S-R-T-D-G-R-G-M-A-I-M-V-S-P-I-K-S-K-T-I-V-R-E-K-S-S-H-A-Q-K-G-D-K-Q-P"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-S-K-L-S-K-I-V-K-N-E-K-R-K-V-I-V-A-R-Y-A-A-R-R-Q-E-L-K-R-I-I-A-A-P-G-T-A-P-E-R-R-D-E-A-Q-A-A-L-Q-K-L-P-R-D-A-S-P-V-R-V-R-S-R-D-V-V-D-G-R-P-R-G-I-L-S-R-F-G-V-S-R-I-R-F-R-E-M-A-H-R-G-E-L-P-G-I-T-K-S-S-W"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-L-G-S-P-L-R-E-Y-E-L-L-V-S-L-G-S-E-F-E-P-E-A-E-S-R-V-R-S-L-F-T-P-V-E-P-E-G-V-T-V-K-H-L-D-V-L-G-I-R-K-F-A-Y-E-I-K-G-R-N-D-G-V-C-V-V-V-R-F-L-A-N-A-G-S-I-A-E-I-G-R-Q-M-R-L-T-E-D-V-I-R-T-K-L-L-R-V-G-R-K"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-G-Y-R-A-K-G-R-R-Q-P-K-A-D-S-V-V-A-P-P-K-R-V-S-I-K-G-L-D-Y-K-D-L-A-S-L-K-R-F-L-S-D-R-G-K-I-R-A-R-R-V-T-G-A-S-I-Q-Q-Q-R-Q-I-A-K-A-I-K-N-A-R-E-M-G-V-I-P-F-K-S-G-V-S-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-R-V-I-L-V-Q-D-V-N-G-L-G-S-V-G-D-V-V-E-V-K-A-G-Y-S-R-N-Y-L-V-P-K-G-M-A-V-R-W-T-E-G-A-Q-K-H-I-G-D-I-S-A-A-R-R-A-R-E-A-A-A-L-Q-E-A-R-D-I-A-N-T-L-A-K-E-A-V-T-R-E-L-R-L-A-A-N-A-G-E-D-G-R-L-F-G-S-V-T-A-A-N-I-A-K-V-L-S-S-A-S-G-H-K-I-D-R-G-K-I-E-I-D-S-P-I-K-T-L-G-E-H-T-V-K-V-K-L-H-P-N-V-K-V-D-I-N-V-V-V-Y-A-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-D-K-K-V-V-G-V-I-K-L-Q-I-Q-A-G-A-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-Y-N-A-A-T-E-S-Q-K-G-N-V-I-P-V-E-I-S-V-Y-E-D-R-S-F-T-F-V-L-K-T-P-P-V-V-E-L-I-K-K-A-A-R-I-S-K-G-S-P-T-P-H-N-L-K-V-A-Q-I-T-P-E-Q-V-K-S-I-A-E-A-K-M-V-D-L-N-A-N-D-I-D-A-A-S-K-I-V-R-G-T-A-R-S-M-G-V-T-V-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-T-K-Q-E-T-V-K-H-L-V-G-V-L-S-D-A-Q-A-I-V-F-T-E-Y-R-G-L-S-A-A-Q-L-R-A-L-R-I-L-L-R-G-D-A-S-Y-L-I-A-K-N-T-L-A-R-I-A-A-Q-Q-V-G-F-N-D-F-A-E-F-L-R-G-P-T-A-I-V-A-V-D-G-D-I-V-S-V-A-K-S-L-R-K-F-A-E-T-D-G-L-L-K-I-K-G-C-F-V-D-G-Q-V-F-G-S-E-H-V-K-R-L-A-E-L-E-S-R-E-V-I-L-A-K-I-A-S-V-T-K-G-A-L-S-S-A-L-G-L-V-S-A-P-L-S-S-A-A-R-V-F-V-A-M-K-N-T-F"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-I-T-T-D-E-L-I-E-S-F-K-E-M-T-L-I-E-L-S-E-F-V-S-K-F-E-E-V-F-K-V-T-A-A-A-P-V-A-A-A-A-A-P-I-E-P-A-A-E-A-A-P-E-K-T-T-F-D-V-I-L-E-A-A-G-D-K-K-I-Q-V-I-K-E-V-R-T-I-T-G-L-G-L-G-E-A-K-A-L-V-D-G-V-P-S-K-V-L-E-G-A-N-K-D-A-A-D-A-A-K-A-Q-L-E-A-A-G-A-Q-V-S-V-K"} +{"text": "### FUNCTION Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis ### SEQUENCE -M-F-V-T-F-E-G-I-D-G-S-G-K-T-A-Q-L-T-A-A-G-E-F-L-K-A-S-G-K-Q-V-V-L-T-R-E-P-G-T-I-S-C-I-R-D-Y-V-L-A-S-D-M-D-I-R-T-E-A-L-L-Y-S-A-D-R-A-E-N-I-A-K-N-V-I-P-A-L-N-A-G-K-V-V-L-Q-D-R-Y-L-D-S-F-L-A-Y-Q-L-A-D-N-K-L-V-E-T-D-I-M-R-L-F-E-F-S-S-Q-G-L-R-P-D-L-T-L-L-F-D-L-T-P-A-C-A-Q-E-R-L-E-N-R-D-R-I-E-R-K-P-I-D-F-H-S-K-V-R-N-I-Y-L-K-L-S-A-D-N-T-D-R-I-R-V-I-D-A-S-Q-S-F-S-K-I-H-Q-Q-V-I-Y-H-I-E-R-K-L-G-G-T-H-S-A"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-G-K-D-R-N-L-S-L-N-S-P-E-S-I-Q-S-V-I-G-D-T-D-I-K-I-A-V-I-A-A-M-W-H-E-K-I-V-R-G-L-I-D-G-A-T-R-E-I-V-S-S-G-S-H-A-E-L-F-R-V-P-G-S-V-E-L-V-L-A-C-K-K-L-L-K-T-F-D-A-A-V-A-L-G-V-I-L-R-G-E-T-D-H-N-T-H-I-A-R-L-V-L-S-G-I-T-D-V-M-L-A-L-E-K-P-I-G-I-G-V-L-T-I-D-T-E-Q-Q-G-L-D-R-S-S-G-D-Y-N-A-G-V-N-A-A-R-A-V-I-R-M-V-R-L-F-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-V-R-R-E-I-P-E-D-P-V-Y-S-S-R-V-V-S-Q-L-I-G-R-V-L-L-S-G-K-K-S-L-A-Q-R-I-V-Y-S-A-L-D-K-V-S-M-K-A-S-E-D-P-V-S-V-L-R-K-A-L-D-N-V-R-P-S-L-E-V-R-S-R-R-V-G-G-S-T-Y-Q-V-P-V-P-V-R-S-H-R-A-D-A-L-A-I-R-W-L-T-V-Y-S-R-A-R-R-E-K-S-M-V-D-R-L-A-S-E-I-L-D-A-S-N-G-V-G-A-T-V-K-C-K-E-D-T-H-R-M-A-E-S-N-R-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-V-Y-P-V-V-E-A-E-S-R-V-G-F-G-K-G-F-A-R-R-A-R-A-A-G-K-I-P-A-V-A-Y-G-L-K-R-A-P-E-H-V-L-L-P-A-A-Q-M-S-L-I-M-R-R-A-N-A-L-L-Q-L-K-I-D-A-R-E-S-L-V-L-I-K-Q-V-Q-R-D-R-I-R-N-I-I-E-H-L-D-M-L-F-V-N-E-D-D-A-V-T-I-R-V-P-L-R-F-V-G-Q-S-Y-A-G-T-V-T-S-V-E-N-Y-S-V-A-V-T-L-Q-V-S-Q-I-P-E-A-L-V-V-D-V-S-G-L-Q-A-G-R-R-I-F-A-S-D-I-A-L-P-D-G-A-L-L-V-S-P-P-R-L-L-I-A-K-V-D-P-V-R-R-A-T-Q-E-P-P-P-D"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-C-V-Y-I-V-A-G-L-G-N-P-G-P-S-Y-D-K-T-R-H-N-V-G-Q-M-V-L-D-I-L-S-G-G-A-R-F-R-R-H-K-T-N-N-F-Y-L-S-L-G-D-I-L-L-V-K-P-D-A-Y-M-N-L-S-G-P-V-I-A-S-L-M-K-F-H-S-V-S-D-L-L-V-L-H-D-D-I-D-L-P-L-G-T-L-R-F-K-Q-G-G-G-T-A-G-H-R-G-L-R-S-I-S-D-C-L-G-S-D-Y-A-R-L-R-V-G-I-G-R-P-E-N-N-Q-S-I-E-D-F-V-L-S-N-F-S-P-V-Q-T-D-I-I-S-R-T-I-Q-L-A-A-E-A-V-L-H-L-R-D-N-G-F-V-G-V-K-Q-F-I-A-Q-T-K-S-P-S-R-T"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-G-E-S-I-T-A-P-E-V-R-L-I-N-S-D-G-G-P-L-G-V-V-S-R-S-V-A-L-R-L-A-G-E-V-G-L-D-L-V-E-V-S-P-F-S-K-P-P-V-V-K-I-M-D-Y-G-K-F-R-Y-E-A-S-Q-K-A-K-E-A-R-R-R-Q-S-G-V-S-V-K-E-V-R-F-R-L-K-I-C-D-N-D-Y-D-V-K-L-R-K-A-I-S-F-L-Q-A-G-D-K-V-K-V-M-I-L-F-R-G-R-E-Q-S-R-P-E-L-G-V-K-L-L-K-K-F-A-D-D-I-S-E-F-G-S-A-D-S-L-S-R-T-D-G-R-G-M-A-I-M-V-S-P-I-K-S-K-T-I-V-R-E-K-S-S-H-A-Q-K-G-D-K-Q-P"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-V-A-R-S-V-N-A-R-K-K-R-R-S-I-L-A-A-A-K-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-V-L-R-S-L-V-Y-A-Y-R-D-R-R-K-R-K-S-S-F-R-K-L-W-I-I-R-I-N-A-A-A-R-M-E-G-V-T-Y-N-R-F-L-Q-G-L-K-L-A-N-I-E-L-D-R-R-S-L-A-H-L-A-V-H-N-P-D-T-F-S-A-L-V-G-V-A-K-D-S-L-K-N-A-P-D-P-V-A-A-P-R-L-R-G-T-S-S-R-T"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-I-K-R-N-R-T-N-E-N-N-R-L-R-N-K-A-V-K-S-E-L-K-T-L-I-R-L-V-K-R-A-A-R-D-N-D-L-P-R-A-E-D-A-L-R-R-A-S-L-K-L-D-R-A-V-S-K-G-V-I-H-P-N-Q-A-A-N-R-K-S-G-I-A-K-L-V-V-A-T-R-L-R-N-S-T-A-G-E"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-G-L-L-Y-L-Q-N-S-S-G-Y-N-D-C-Y-F-K-T-E-S-L-V-D-F-L-Y-R-T-L-F-I-D-K-G-S-Y-L-G-V-S-F-I-T-A-A-E-M-R-D-L-K-I-K-H-F-G-V-N-E-D-S-D-V-L-S-F-P-I-D-E-I-A-P-G-S-E-N-S-L-V-Y-G-V-L-G-D-I-V-V-C-P-E-T-V-M-R-Q-A-V-R-H-P-F-E-H-E-I-Y-L-L-V-V-H-G-F-L-H-L-L-G-F-D-H-S-D-A-P-S-K-K-E-M-F-S-L-Q-A-K-L-I-E-D-F-F-A-L-E-N-L-G-T-P-S-E-E-I-T-I-T-P-D-L-R-P-S-L-G-R-I"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-Q-L-F-D-L-W-T-D-L-L-D-L-L-T-I-V-A-G-P-T-A-V-G-K-G-T-V-I-S-H-L-R-K-C-H-P-Q-V-K-V-S-I-S-A-T-T-R-E-P-R-D-S-E-R-D-G-I-D-Y-Y-F-V-T-D-E-V-F-D-C-M-V-R-S-G-Q-M-L-E-W-A-T-V-H-G-L-H-K-Y-G-T-P-K-E-E-V-E-R-L-L-H-T-G-Q-P-V-I-L-E-I-D-L-Q-G-M-R-K-V-R-K-I-L-P-A-V-R-T-V-I-L-L-P-P-A-W-D-D-L-I-C-R-I-K-R-R-G-S-E-S-Q-D-E-I-D-A-R-L-A-T-A-K-K-E-L-E-A-I-G-E-F-D-Y-K-I-V-N-A-D-V-E-I-A-A-N-E-L-W-L-A-M-N-R-V"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-V-K-S-V-A-D-R-F-F-L-G-L-D-F-G-S-T-R-I-G-V-A-R-N-C-G-S-L-A-V-P-V-G-V-L-P-R-A-S-C-A-E-I-L-G-Y-I-S-R-Y-S-I-D-E-V-V-I-G-L-P-L-T-L-A-G-K-E-K-Q-S-A-R-L-A-K-E-F-S-R-F-L-V-S-S-G-V-Q-V-R-F-F-D-E-R-F-T-T-V-I-A-T-Q-K-F-Y-S-L-G-K-G-V-K-Q-I-R-K-C-V-D-A-A-A-A-T-V-M-L-Q-L-F-L-D-M-E-V-K-V-D-P-L-E-R-K-P"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-C-V-A-P-T-P-S-H-L-V-W-V-D-C-E-M-T-G-L-N-P-E-R-D-E-L-L-E-V-A-V-I-V-T-D-K-D-L-L-P-L-D-E-G-V-N-V-V-V-S-P-S-S-E-A-L-G-A-M-D-N-Y-V-A-R-M-H-R-V-S-G-L-L-D-E-L-S-N-G-V-P-V-S-E-A-Q-A-M-V-K-E-Y-I-T-K-H-I-K-T-G-G-I-M-S-G-N-S-I-A-T-D-R-L-F-I-T-R-Y-M-P-D-V-H-A-I-L-H-Y-R-M-I-D-V-S-S-I-K-E-L-A-V-R-W-A-P-E-I-Y-S-G-A-P-N-K-K-G-G-H-R-A-M-A-D-V-L-E-S-I-A-E-L-A-Y-Y-R-E-H-F-L-T-G-T-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-R-K-L-D-M-D-K-G-A-I-I-S-E-Y-G-L-S-K-G-D-T-G-S-P-E-V-Q-I-A-L-L-T-A-R-I-A-R-L-T-Q-H-L-K-E-H-S-F-D-H-H-S-R-R-G-L-M-L-M-V-G-R-R-R-R-L-L-S-Y-L-H-G-V-D-V-S-R-Y-R-A-I-L-S-N-L-G-L-R-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-F-A-Q-P-H-N-P-L-L-P-S-V-P-D-I-V-F-S-A-I-V-L-A-I-V-L-P-F-F-W-W-F-V-I-P-R-I-S-K-L-L-S-D-R-S-S-L-I-E-G-K-I-S-E-A-A-S-A-H-A-R-A-L-E-T-L-E-L-R-K-Q-Q-L-D-E-A-K-S-E-A-S-Q-I-R-Q-E-A-R-D-D-A-Q-L-I-L-Q-Q-A-R-E-T-A-D-E-T-A-E-R-V-M-L-H-A-R-E-Q-I-Q-A-E-K-A-A-A-L-L-S-L-R-S-E-I-A-T-L-A-L-A-A-A-G-K-A-V-S-E-K-L-D-D-D-K-K-S-R-E-L-V-S-A-S-I-A-K-M-A-E-D-A-G"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-G-I-M-C-S-G-D-V-S-E-R-M-N-K-T-I-E-L-L-K-E-Q-F-L-S-I-H-S-G-R-V-N-S-G-Q-F-E-K-V-M-V-D-C-E-G-A-S-V-P-L-V-S-L-A-S-I-R-V-L-N-A-N-T-I-V-V-T-P-Y-D-S-A-L-L-S-Q-I-D-R-A-L-R-N-V-P-N-I-G-T-P-G-N-D-G-E-C-I-K-I-V-M-P-Q-L-T-E-A-R-R-H-E-Y-V-K-Q-A-R-V-K-A-E-E-A-R-V-S-A-R-N-I-R-R-K-A-R-A-S-L-D-A-M-G-L-A-K-D-E-I-V-R-R-E-K-E-L-D-K-L-T-K-D-V-I-S-V-V-D-D-L-L-R-H-K-E-S-E-L-L-R-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-H-A-L-D-A-L-D-A-L-S-I-K-A-D-I-P-D-F-S-P-G-D-T-V-R-V-Y-V-N-I-T-E-G-D-R-S-R-V-Q-V-F-Q-G-V-V-I-A-R-R-G-F-G-V-R-Q-T-F-T-V-R-K-I-S-F-Q-V-G-V-E-R-I-F-P-L-H-S-P-S-I-N-R-I-E-V-V-T-K-G-S-V-R-R-A-K-L-Y-Y-I-R-K-L-R-G-K-K-A-K-V-K-Q-K-R-E-L"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-G-G-T-F-D-P-I-H-H-G-H-L-V-V-A-S-E-V-A-S-R-F-C-L-D-E-V-I-F-V-P-T-G-R-P-P-H-K-K-E-V-S-D-P-W-H-R-Y-L-M-A-V-I-A-T-A-S-N-Q-R-F-S-V-S-K-I-D-I-E-R-T-G-P-T-F-T-V-D-T-L-R-E-L-R-E-Q-L-Q-S-S-D-L-F-F-I-T-G-T-D-A-L-A-R-I-F-S-W-K-D-A-D-T-L-W-S-L-A-H-F-V-A-V-S-R-P-G-H-E-V-V-D-I-P-N-D-R-I-S-F-L-E-V-P-A-M-A-I-S-S-S-N-C-R-E-R-V-R-S-G-L-P-I-W-Y-L-V-P-E-G-V-V-Q-Y-I-A-K-H-G-L-Y-R-S-L-Y-G"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-V-K-A-S-G-F-Q-R-L-V-E-V-G-S-V-I-S-I-D-P-T-N-V-D-S-G-G-F-V-H-L-P-V-L-L-L-V-D-G-A-E-V-V-S-D-P-D-K-L-R-L-A-R-V-S-A-K-F-L-R-K-L-R-G-P-K-V-R-I-H-K-F-K-N-K-T-G-Y-H-K-R-Q-G-H-R-Q-G-V-Y-V-F-S-V-T-S-I-E-R-G-D"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-E-T-K-Q-T-V-F-D-R-L-L-Q-E-R-I-V-W-L-G-E-A-I-D-D-K-L-A-N-E-I-C-A-K-I-L-L-L-N-A-D-D-P-K-E-D-I-F-L-Y-I-N-S-P-G-G-S-I-T-A-G-M-A-I-Y-D-T-M-Q-F-V-S-N-D-I-V-T-V-G-I-G-M-A-A-S-M-G-Q-V-L-L-T-S-G-T-Q-N-K-R-Y-I-M-P-N-A-R-V-L-L-H-Q-P-L-A-G-F-G-G-T-A-S-D-I-Q-T-Q-A-K-L-I-L-D-M-K-Y-R-L-S-Q-I-T-A-S-R-T-G-K-T-V-E-Q-I-M-E-D-G-D-R-D-H-W-F-T-A-E-E-A-L-E-Y-G-F-V-D-H-I-R-T-E"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-V-E-V-L-F-K-G-G-Y-T-P-Q-R-A-F-D-G-D-A-G-F-D-L-Q-S-S-H-T-A-V-I-Q-P-R-C-R-Q-V-V-K-T-G-I-A-I-A-L-P-D-G-Y-A-G-F-I-M-P-R-S-G-L-A-S-E-N-G-I-T-L-V-N-S-P-G-V-I-D-A-G-Y-R-G-E-I-S-V-V-L-I-N-T-D-L-H-Q-A-F-H-I-S-Q-G-D-R-I-A-Q-L-V-I-M-P-V-C-H-A-S-F-I-E-V-D-T-L-P-G-S-A-R-G-I-S-A-F-G-S-S-G-R-H-D-T-R-G"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-G-G-L-K-K-A-M-V-Y-L-G-L-A-E-D-N-Q-E-L-H-S-A-P-S-G-M-S-H-L-R-R-V-P-H-P-K-Q-Q-M-S-E-I-F-T-F-H-P-K-K-Y-S-E-V-S-G-I-V-E-R-F-R-Q-N-I-P-V-I-I-D-M-S-Q-L-S-D-T-D-A-R-R-M-I-D-F-A-S-G-L-S-Q-G-L-V-G-K-I-E-R-V-V-G-K-V-F-L-L-S-P-E-H-I-S-I-S-T-E-S-K-K-E-E"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-K-D-G-V-I-E-L-E-G-S-V-L-E-A-L-P-N-A-T-F-R-V-E-L-S-N-G-H-K-V-L-A-H-I-S-G-R-M-R-Q-H-Y-I-R-I-L-P-E-D-R-V-V-V-E-L-S-P-Y-D-L-A-R-G-R-I-V-Y-R-Y-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-I-K-L-H-H-L-R-P-A-P-G-S-R-R-A-R-I-R-V-G-R-G-E-G-S-K-G-K-T-A-G-R-G-T-K-G-T-K-A-R-A-P-V-R-P-G-F-A-G-G-Q-I-P-L-H-M-S-I-P-K-L-K-G-F-K-N-H-K-K-V-E-Y-S-V-I-S-I-K-R-L-C-E-A-Y-P-S-G-G-V-V-T-R-D-N-V-M-S-V-I-G-K-K-R-G-F-V-K-L-L-S-D-G-E-V-T-V-K-F-D-I-T-V-D-K-A-S-A-A-A-V-E-K-I-T-S-A-A-G-T-V-T-Q-A-R"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-L-T-S-R-A-S-A-R-K-R-R-H-V-R-L-R-K-K-I-S-G-T-C-D-R-P-R-L-S-V-T-R-S-N-R-H-V-F-V-Q-A-V-D-D-I-S-G-K-T-L-V-S-A-S-T-M-E-K-D-I-R-A-L-E-L-G-K-T-E-R-A-L-A-V-G-K-L-V-A-Q-R-A-L-A-V-G-V-K-S-A-V-F-D-R-G-G-C-K-Y-T-G-R-V-A-A-V-A-E-G-A-R-E-A-G-L-Q-T"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-L-P-I-E-I-P-V-G-V-E-V-C-V-N-G-R-T-V-S-I-T-G-P-K-G-S-L-Y-L-D-I-A-E-Q-I-G-V-S-V-S-D-G-K-V-L-V-S-R-S-D-D-S-R-T-A-R-A-L-H-G-L-T-R-A-L-I-A-N-N-V-H-G-V-L-H-G-Y-T-K-T-L-E-I-V-G-T-G-Y-R-V-S-K-K-G-E-N-L-E-L-A-L-G-F-S-H-P-V-F-V-D-P-V-P-G-V-S-F-G-V-E-G-N-S-K-I-I-V-S-G-I-D-K-Q-A-V-G-E-A-A-A-S-I-R-K-L-S-K-P-E-P-Y-K-G-K-G-I-R-Y-S-D-E-I-V-R-R-K-V-G-K-A-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-L-S-D-M-F-S-R-I-R-N-A-N-Q-V-L-H-K-K-V-T-V-P-S-S-R-L-K-V-S-I-A-D-L-L-K-R-E-G-Y-I-L-D-Y-S-V-I-D-E-H-P-G-Q-L-L-V-I-E-L-K-Y-G-P-D-K-S-R-A-L-V-G-L-K-R-V-S-K-P-G-L-R-V-Y-A-K-S-S-N-L-P-E-V-F-G-G-L-G-I-A-I-L-S-T-S-S-G-L-L-T-C-S-Q-A-R-K-K-G-V-G-G-E-V-L-A-Y-A-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-C-Y-T-P-R-L-L-T-R-Y-R-E-E-I-V-P-V-L-M-S-R-F-D-I-N-N-V-H-Q-V-P-S-I-T-K-I-V-V-N-S-G-V-G-D-A-A-R-D-S-K-I-I-E-G-A-V-S-D-I-T-L-I-T-G-Q-K-P-R-I-N-R-A-K-Q-S-I-A-K-F-K-L-R-E-G-Q-A-V-G-V-T-A-T-L-R-G-R-R-M-W-E-F-L-D-R-L-L-T-L-A-L-P-R-I-R-D-F-R-G-I-S-D-K-Q-F-D-G-H-G-N-Y-T-F-G-L-S-E-Q-G-I-F-H-E-I-D-Q-D-K-I-D-R-V-R-G-M-D-I-T-V-V-T-T-S-S-S-D-D-M-A-R-A-L-L-G-E-L-G-F-P-F-K-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-V-K-I-R-K-G-D-L-V-Q-V-I-T-G-S-K-T-G-G-K-K-G-K-Q-G-R-V-L-A-V-S-G-D-R-V-W-V-E-G-V-N-L-T-T-R-H-R-K-R-V-T-N-D-K-G-T-S-S-G-G-L-E-K-R-E-S-P-M-H-I-S-N-V-A-L-V-D-P-E-T-G-A-P-T-K-V-G-F-L-V-K-T-S-G-D-K-T-V-R-V-R-F-A-K-K-S-G-K-E-L-T"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-T-G-A-K-S-L-S-V-I-R-V-L-G-G-S-N-R-R-F-G-S-L-G-D-V-V-V-A-S-V-K-D-A-V-P-G-S-S-A-V-K-K-G-D-V-V-K-A-V-I-V-R-S-T-K-E-V-R-R-T-D-G-S-Y-I-R-F-D-D-N-A-A-V-I-L-R-P-D-N-D-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-R-K-F-T-R-I-I-S-L-A-P-E-V-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-Q-Q-R-G-Y-R-K-S-R-R-G-Y-V-T-S-N-S-M-D-K-T-I-V-V-K-I-E-D-R-V-K-H-A-L-Y-G-K-V-I-R-K-T-S-K-V-K-A-H-D-Q-G-S-I-A-G-V-G-D-L-V-L-I-S-E-T-R-P-I-S-A-T-K-R-W-R-L-V-Q-I-L-E-K-A-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-M-L-I-P-K-K-V-K-F-R-K-Q-H-R-P-N-R-K-G-M-S-G-C-G-T-R-I-V-F-G-D-Y-G-I-Q-A-L-S-R-A-Y-V-T-N-R-Q-V-E-S-A-R-I-A-M-T-R-H-I-R-R-G-G-R-V-W-I-N-I-Y-P-D-R-P-L-T-K-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-Y-W-V-A-N-I-R-P-G-R-I-M-F-E-V-S-G-V-S-E-S-L-A-K-E-A-L-M-R-A-I-H-K-L-P-L-R-A-R-I-V-E-R-Q-E-F-D-D-A-G-L"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-E-E-K-D-T-P-L-E-A-F-A-S-L-K-H-S-G-V-T-P-Q-K-V-R-R-I-V-D-L-I-R-G-R-S-V-D-E-A-L-A-I-L-R-F-S-P-H-S-A-S-G-I-L-Y-K-L-I-V-S-A-Q-A-N-Y-A-N-L-L-G-R-D-D-D-L-F-V-S-S-V-Y-V-D-E-G-K-T-Y-K-R-G-R-P-R-A-R-G-S-S-S-R-I-L-K-R-G-S-H-V-T-V-T-L-S-K-E-V-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-V-D-M-H-L-L-K-K-V-R-A-G-N-E-S-K-D-R-N-M-I-K-T-W-S-R-R-S-M-I-I-P-E-M-L-G-H-T-I-A-V-H-D-G-R-R-H-I-P-V-F-I-T-E-S-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-V-K-D-D-R-K-A-R-R-R"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-E-E-Q-K-I-R-I-R-L-K-S-Y-S-H-E-I-I-D-V-S-A-K-K-I-V-D-T-V-T-R-A-G-A-T-I-V-G-P-V-P-L-P-T-K-K-S-V-V-C-V-I-R-S-P-H-R-H-K-D-S-R-E-H-F-E-M-R-T-H-K-R-L-I-N-V-V-D-L-T-P-R-A-V-D-A-L-M-R-L-D-L-S-S-E-V-N-V-E-I-K-L"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-S-K-L-S-K-I-V-K-N-E-K-R-K-V-I-V-A-R-Y-A-A-R-R-Q-E-L-K-R-I-I-A-A-P-G-T-A-P-E-R-R-D-E-A-Q-A-A-L-Q-K-L-P-R-D-A-S-P-V-R-V-R-S-R-D-V-V-D-G-R-P-R-G-I-L-S-R-F-G-V-S-R-I-R-F-R-E-M-A-H-R-G-E-L-P-G-I-T-K-S-S-W"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-L-G-S-P-L-R-E-Y-E-L-L-V-S-L-G-S-E-F-E-P-E-A-E-S-R-V-R-S-L-F-T-P-V-E-P-E-G-V-T-V-K-H-L-D-V-L-G-V-R-K-F-A-Y-E-I-K-G-R-N-D-G-V-C-V-V-V-R-L-L-A-N-A-G-S-I-A-E-I-G-R-Q-M-R-L-T-E-D-V-I-R-T-K-L-L-R-V-G-R-K"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-G-Y-R-A-K-G-R-R-Q-P-K-A-D-S-V-V-A-P-P-K-R-V-S-I-K-G-L-D-Y-K-D-L-A-S-L-K-R-F-L-S-D-R-G-K-I-R-A-R-R-V-T-G-A-S-I-Q-Q-Q-R-Q-I-A-K-A-I-K-N-A-R-E-M-G-V-I-P-F-K-S-G-V-S-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-R-V-I-L-V-Q-D-V-N-G-L-G-S-V-G-D-V-V-E-V-K-A-G-Y-S-R-N-Y-L-V-P-K-G-M-A-V-R-W-T-E-G-A-Q-K-H-I-G-D-I-S-A-A-R-R-A-R-E-A-A-A-L-Q-E-A-R-D-I-A-N-T-L-T-K-E-A-V-T-R-E-L-R-L-A-A-N-A-G-E-D-G-R-L-F-G-S-V-T-A-A-N-I-A-K-V-L-S-S-A-S-G-H-K-I-D-R-G-K-I-E-I-D-S-P-I-K-T-L-G-E-H-T-V-K-V-K-L-H-P-N-V-K-V-D-I-N-V-V-V-Y-A-E"} +{"text": "### FUNCTION Involved in the degradation and recycling of damaged RNA It is itself a target for degradation by the ATP-dependent protease Lon ### SEQUENCE -M-T-D-T-H-S-I-A-Q-P-L-E-A-E-V-S-P-A-N-N-R-Q-L-T-V-S-Y-A-S-R-Y-P-D-Y-S-R-I-P-A-I-T-L-K-G-Q-W-L-E-A-A-G-F-A-T-G-T-A-V-D-V-K-V-M-E-G-C-I-V-L-T-A-Q-P-A-A-A-E-E-S-E-L-M-Q-S-L-R-K-V-C-K-L-S-A-R-K-Q-R-Q-V-Q-E-F-I-G-V-I-T-G-K-Q-K-V-A"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-S-A-N-E-N-N-L-I-W-I-D-L-E-M-T-G-L-D-P-E-R-D-R-I-I-E-I-A-T-L-V-T-D-A-N-L-N-I-L-A-E-G-P-T-I-A-V-H-Q-S-D-E-Q-L-A-L-M-D-D-W-N-V-R-T-H-T-A-S-G-L-V-E-R-V-K-A-S-T-M-G-D-R-E-A-E-L-A-T-L-E-F-L-K-Q-W-V-P-A-G-K-S-P-I-C-G-N-S-I-G-Q-D-R-R-F-L-F-K-Y-M-P-E-L-E-V-Y-F-H-Y-R-Y-L-D-V-S-T-L-K-E-L-A-R-R-W-K-P-E-I-L-D-G-F-T-K-Q-G-T-H-Q-A-M-D-D-I-R-E-S-V-A-E-L-A-Y-Y-R-E-H-F-I-K-L"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-T-H-D-N-K-L-Q-V-E-A-I-K-R-G-T-V-I-D-H-I-P-A-Q-I-G-F-K-L-L-S-L-F-K-L-T-E-T-D-Q-R-I-T-I-G-L-N-L-P-S-G-E-M-G-R-K-D-L-I-K-I-E-N-T-F-L-S-E-E-Q-V-D-Q-L-A-L-Y-A-P-Q-A-T-V-N-R-I-D-N-Y-E-V-V-G-K-S-R-P-S-L-P-E-R-I-D-N-V-L-V-C-P-N-S-N-C-I-S-H-A-E-P-V-S-S-S-F-A-V-R-K-R-A-N-D-I-A-L-K-C-K-Y-C-E-K-E-F-S-H-N-V-V-L-A-N"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-S-H-P-A-L-T-Q-L-R-A-L-R-Y-F-K-E-I-P-A-L-D-P-Q-L-L-D-W-L-L-L-E-D-S-M-T-K-R-F-E-Q-Q-G-K-T-V-S-V-T-M-I-R-E-G-F-V-E-Q-N-E-I-P-E-E-L-P-L-L-P-K-E-S-R-Y-W-L-R-E-I-L-L-C-A-D-G-E-P-W-L-A-G-R-T-V-V-P-V-S-T-L-S-G-P-E-L-A-L-Q-K-L-G-K-T-P-L-G-R-Y-L-F-T-S-S-T-L-T-R-D-F-I-E-I-G-R-D-A-G-L-W-G-R-R-S-R-L-R-L-S-G-K-P-L-L-L-T-E-L-F-L-P-A-S-P-L-Y"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-D-S-E-F-H-R-L-A-D-Q-L-W-L-T-I-E-E-R-L-D-D-R-D-G-D-S-D-I-D-C-E-I-N-G-G-V-L-T-I-T-F-E-N-G-S-K-I-I-I-N-R-Q-E-P-L-H-Q-V-W-L-A-T-K-Q-G-G-Y-H-F-D-L-K-G-D-E-W-I-C-D-R-S-G-E-T-F-W-D-L-L-E-Q-A-A-T-Q-Q-A-G-E-T-V-S-F-R"} +{"text": "### FUNCTION May act as a transcriptional regulator of dctA ### SEQUENCE -M-F-L-I-I-T-R-D-T-M-F-F-T-A-M-K-N-I-L-S-K-G-N-V-V-H-I-Q-N-E-E-E-I-D-V-M-L-H-Q-N-A-F-V-I-I-D-T-L-M-N-N-V-F-H-S-N-F-L-T-Q-I-E-R-L-K-P-V-H-V-I-V-F-S-P-F-N-I-K-R-C-L-G-K-V-P-V-T-F-V-P-R-T-I-T-I-I-D-F-V-A-L-I-N-G-S-Y-C-S-V-P-E-A-N-V-S-L-S-R-K-Q-H-Q-V-L-S-C-I-A-N-Q-M-T-T-E-D-I-L-E-K-L-K-I-S-L-K-T-F-Y-C-H-K-H-N-I-M-M-I-L-N-L-K-R-I-N-E-L-V-R-H-Q-H-I-D-Y-L-V"} +{"text": "### FUNCTION May function as a transcriptional regulator that controls feoABC expression ### SEQUENCE -M-A-S-L-I-Q-V-R-D-L-L-A-L-R-G-R-M-E-A-T-Q-I-S-Q-T-L-N-T-P-Q-P-M-I-N-A-M-L-Q-Q-L-E-S-M-G-K-A-V-R-I-Q-E-E-P-D-G-C-L-S-G-S-C-K-S-C-P-E-G-K-A-C-L-R-E-W-W-A-L-R"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-R-F-A-I-V-V-T-G-P-A-Y-G-T-Q-Q-A-S-S-A-F-Q-F-A-Q-A-L-I-A-E-G-H-K-L-S-S-V-F-F-Y-R-E-G-V-Y-N-A-N-Q-L-T-S-P-A-S-D-E-F-D-L-V-R-G-W-Q-Q-L-N-A-Q-H-G-V-A-L-N-I-C-V-A-A-A-L-R-R-G-I-V-D-E-T-E-A-G-R-L-G-L-A-S-S-N-L-Q-P-G-F-T-L-S-G-L-G-A-L-A-E-A-S-L-T-C-D-R-V-V-Q-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-K-R-I-A-F-V-F-S-T-A-P-H-G-T-A-A-G-R-E-G-L-D-A-L-L-A-T-S-A-L-T-D-D-L-A-V-F-F-I-A-D-G-V-F-Q-L-L-S-G-Q-K-P-D-A-V-L-A-R-D-Y-I-A-T-F-K-L-L-S-L-Y-D-I-E-Q-C-W-V-C-A-A-S-L-R-E-R-G-L-D-P-Q-T-P-F-V-V-E-A-T-P-L-E-A-D-A-L-R-R-E-L-A-N-Y-D-V-I-L-R-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-L-H-T-L-H-R-S-P-W-L-T-D-F-A-A-L-L-R-L-L-S-E-G-D-E-L-L-L-L-Q-D-G-V-T-A-A-V-D-G-N-R-Y-L-E-S-L-R-N-A-P-I-K-V-Y-A-L-N-E-D-L-I-A-R-G-L-T-G-Q-I-L-N-D-I-I-P-I-D-Y-T-D-F-V-R-L-T-V-K-H-S-S-Q-M-A-W"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-T-S-L-Y-L-A-S-G-S-P-R-R-Q-E-L-L-A-Q-L-G-V-T-F-E-R-I-V-T-G-I-E-E-Q-R-Q-P-Q-E-S-A-Q-Q-Y-V-V-R-L-A-R-E-K-A-Q-A-G-V-A-Q-T-A-Q-D-L-P-V-L-G-A-D-I-I-V-I-L-N-G-E-V-L-E-K-P-R-D-A-E-H-A-A-Q-M-L-R-K-L-S-G-Q-T-H-Q-V-M-T-A-V-A-L-A-D-S-Q-H-I-L-D-C-L-V-V-T-D-V-T-F-R-T-L-T-D-E-D-I-A-G-Y-V-A-S-G-E-P-L-D-K-A-G-A-Y-G-I-Q-G-L-G-G-C-F-V-R-K-I-N-G-S-Y-H-A-V-V-G-L-P-L-V-E-T-Y-E-L-L-S-N-F-N-A-L-R-E-K-R-D-K-H-D-G"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-G-T-L-L-A-F-D-F-G-T-K-S-I-G-V-A-V-G-Q-R-I-T-G-T-A-R-P-L-P-A-I-K-A-Q-D-G-T-P-D-W-N-L-I-E-R-L-L-K-E-W-Q-P-D-E-I-I-V-G-L-P-L-N-M-D-G-T-E-Q-P-L-T-A-R-A-R-K-F-A-N-R-I-H-G-R-F-G-V-E-V-K-L-H-D-E-R-L-S-T-V-E-A-R-S-G-L-F-E-Q-G-G-Y-R-A-L-N-K-G-K-V-D-S-A-S-A-V-I-I-L-E-S-Y-F-E-Q-G-Y"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-D-I-N-N-K-A-R-I-H-W-A-C-R-R-G-M-R-E-L-D-I-S-I-M-P-F-F-E-H-E-Y-D-S-L-S-D-D-E-K-R-I-F-I-R-L-L-E-C-D-D-P-D-L-F-N-W-L-M-N-H-G-K-P-A-D-A-E-L-E-I-M-V-R-L-I-Q-T-R-N-R-E-R-G-P-V-A-I"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-G-K-L-T-L-L-L-L-A-I-L-V-W-L-Q-Y-S-L-W-F-G-K-N-G-I-H-D-Y-T-R-V-N-D-D-V-A-A-L-Q-A-T-N-A-K-L-K-A-R-N-D-Q-L-F-A-E-I-D-D-L-N-G-G-Q-E-A-L-E-E-R-A-R-N-E-L-S-M-T-R-P-G-E-T-F-Y-R-L-V-P-D-A-S-K-R-A-Q-S-A-G-Q-N-N-R"} +{"text": "### FUNCTION Has NMN aminohydrolase activity, not active on other substrates ### SEQUENCE -M-T-D-S-E-L-M-Q-L-S-E-Q-V-G-Q-A-L-K-A-R-G-A-T-V-T-T-A-E-S-C-T-G-G-W-V-A-K-V-I-T-D-I-A-G-S-S-A-W-F-E-R-G-F-V-T-Y-S-N-E-A-K-A-Q-M-I-G-V-R-E-E-T-L-A-Q-H-G-A-V-S-E-P-V-V-V-E-M-A-I-G-A-L-K-A-A-R-A-D-Y-A-V-S-I-S-G-I-A-G-P-D-G-G-S-E-E-K-P-V-G-T-V-W-F-A-F-A-T-A-R-G-E-G-I-T-W-R-E-C-F-S-G-D-R-D-A-V-R-R-Q-A-T-A-Y-A-L-Q-T-L-W-Q-Q-F-L-Q-N-T"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-T-V-D-H-T-R-M-E-A-P-A-V-R-V-A-K-T-M-N-T-P-H-G-D-A-I-T-V-F-D-L-R-F-C-V-P-N-K-E-V-M-P-E-R-G-I-H-T-L-E-H-L-F-A-G-F-M-R-N-H-L-N-G-N-G-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-T-P-D-E-Q-R-V-A-D-A-W-K-A-A-M-E-D-V-L-K-V-Q-D-Q-N-Q-I-P-E-L-N-V-Y-Q-C-G-T-Y-Q-M-H-S-L-Q-E-A-Q-D-I-A-R-S-I-L-E-R-E-V-R-I-N-S-N-E-E-L-A-L-P-K-E-K-L-Q-E-L-H-I"} +{"text": "### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-T-G-I-Q-I-T-K-A-A-N-A-D-L-L-N-S-F-W-L-L-D-S-E-K-G-E-A-R-C-I-V-A-K-A-G-Y-A-E-D-E-V-V-A-V-S-K-L-G-D-I-E-Y-R-E-V-P-V-E-V-K-P-E-V-R-V-E-G-G-Q-H-L-N-V-N-V-L-R-R-E-T-L-E-D-A-V-K-H-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-A-R-T-F-T-E-S-L"} +{"text": "### FUNCTION Exporter of O-acetylserine and cysteine ### SEQUENCE -M-T-P-I-L-L-S-A-F-W-T-Y-T-L-I-T-A-M-T-P-G-P-N-N-I-L-A-L-S-S-A-T-S-H-G-F-R-Q-S-T-R-V-L-A-G-M-S-L-G-F-L-I-V-M-L-L-C-A-G-I-S-F-S-L-A-V-I-D-P-A-A-V-H-L-L-S-W-A-G-A-A-Y-I-V-W-L-A-W-K-I-A-T-S-P-T-K-E-D-G-L-Q-A-K-P-I-S-F-W-A-S-F-A-L-Q-F-V-N-V-K-I-I-L-Y-G-V-T-A-L-S-T-F-V-L-P-Q-T-Q-A-L-S-W-V-V-G-V-S-V-L-L-A-M-I-G-T-F-G-N-V-C-W-A-L-A-G-H-L-F-Q-R-L-F-R-Q-Y-G-R-Q-L-N-I-V-L-A-L-L-L-V-Y-C-A-V-R-I-F-Y"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-L-G-L-G-T-D-I-V-E-I-A-R-I-E-A-V-I-A-R-S-G-E-R-L-A-R-R-V-L-S-D-N-E-W-A-I-W-K-T-H-H-Q-P-V-R-F-L-A-K-R-F-A-V-K-E-A-A-A-K-A-F-G-T-G-I-R-N-G-L-A-F-N-Q-F-E-V-F-N-D-E-L-G-K-P-R-L-R-L-W-G-E-A-L-K-L-A-E-K-L-G-V-V-N-M-H-V-T-L-A-D-E-R-H-Y-A-C-A-T-V-I-I-E-S"} +{"text": "### FUNCTION Part of the multicomponent 3-phenylpropionate dioxygenase Converts 3-phenylpropionic acid , respectively ### SEQUENCE -M-S-A-Q-V-S-L-E-L-H-H-R-I-S-Q-F-L-F-H-E-A-S-L-L-D-D-W-K-F-R-D-W-L-A-Q-L-D-E-E-I-R-Y-T-M-R-T-T-V-N-A-Q-T-R-D-R-R-K-G-V-Q-P-P-T-T-W-I-F-N-D-T-K-D-Q-L-E-R-R-I-A-R-L-E-T-G-M-A-W-A-E-E-P-P-S-R-T-R-H-L-I-S-N-C-Q-V-S-E-T-D-I-P-N-V-F-A-V-R-V-N-Y-L-L-Y-R-A-Q-K-E-R-D-E-T-F-Y-V-G-T-R-F-D-K-V-R-R-L-E-D-D-N-W-R-L-L-E-R-D-I-V-L-D-Q-A-V-I-T-S-H-N-L-S-V-L-F"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-R-T-I-S-Y-S-E-A-R-Q-N-L-S-A-T-M-M-K-A-V-E-D-H-A-P-I-L-I-T-R-Q-N-G-E-A-C-V-L-M-S-L-E-E-Y-N-S-L-E-E-T-A-Y-L-L-R-S-P-A-N-A-R-R-L-M-D-S-I-D-S-L-K-S-G-K-G-T-E-K-D-I-I-E-W-V-M-L-P-T-Y"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane Required to maintain the reduced state of SoxR ### SEQUENCE -M-T-D-Y-L-L-L-F-V-G-T-V-L-V-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-L-E-T-A-M-G-M-G-L-A-T-T-F-V-M-T-L-T-S-I-C-A-W-L-I-D-T-W-I-L-I-P-L-N-L-I-Y-L-R-T-L-A-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-V-V-R-K-T-S-P-V-L-Y-R-L-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-I-N-L-G-H-N-F-L-Q-S-A-L-Y-G-F-S-A-A-V-G-F-S-L-V-M-V-L-F-A-A-I-R-E-R-L-A-V-A-D-V-P-A-P-F-R-G-N-A-I-A-L-I-T-A-G-L-M-S-L-A-F-M-G-F-S-G-L-V-K-L"} +{"text": "### FUNCTION Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle Catalyzes the conversion of ### SEQUENCE -M-H-V-T-L-V-E-I-N-V-H-E-D-K-V-D-E-F-I-E-V-F-R-Q-N-H-L-G-S-V-Q-E-E-G-N-L-R-F-D-V-L-Q-D-P-E-V-N-S-R-F-Y-I-Y-E-A-Y-K-D-E-D-T-V-A-F-H-K-T-T-P-H-Y-K-T-C-V-A-K-L-E-S-L-M-T-G-P-R-K-K-R-L-F-N-G-L-M-P"} +{"text": "### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation ### SEQUENCE -M-K-W-I-V-I-D-T-V-I-Q-P-S-C-G-I-S-F-S-V-I-W-S-K-I-K-L-I-I-W-Y-Q-S-D-A-F-L-P-P-E-S-I-F-T-L-T-H-T-G-I-M-L-N-N-K-V-L-P-V-T-I-Y-N-V-V-P-F-N-K-T-F-W-N-L-I-K-N-S-Q-E-C-P-T-N-T-D-N-V-L-N-E-C-F-N-N-R-C-T-L-Q-I-C-P-Y-G-L-K-Q-Q-S-P"} +{"text": "### FUNCTION Probably mediates the hydrolysis of some nucleoside diphosphate derivatives ### SEQUENCE -M-E-Y-R-S-L-T-L-D-D-F-L-S-R-F-Q-L-L-R-P-Q-I-N-R-E-P-L-N-H-R-Q-A-A-V-L-I-P-I-V-R-R-P-Q-P-G-L-L-L-T-Q-R-S-I-H-L-R-K-H-A-G-Q-V-A-F-P-G-G-A-V-D-D-T-D-A-S-V-I-A-A-A-L-R-E-A-E-E-E-V-A-I-P-P-S-A-V-E-V-I-G-V-L-P-P-V-D-S-V-T-G-Y-Q-V-T-P-V-V-G-I-I-P-P-D-L-P-Y-R-A-S-E-D-E-V-S-A-V-F-E-M-P-L-A-Q-A-L-H-L-G-R-Y-H-P-L-D-I-Y-R-R-G-D-S-H-R-V-W-L-S-W-Y-E-Q-Y-F-V-W-G-M-T-A-G-I-I-R-E-L-A-L-Q-I-G-V-T-P"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-I-K-L-I-V-G-L-A-N-P-G-A-E-Y-A-A-T-R-H-N-A-G-A-W-F-V-D-L-L-A-E-R-L-R-A-P-L-R-E-E-A-K-F-F-G-Y-T-S-R-V-T-L-G-S-E-D-V-R-L-L-V-P-T-T-F-M-N-L-S-G-K-A-V-A-A-M-A-S-F-F-R-I-N-P-D-E-I-L-V-A-H-D-E-L-D-L-P-P-G-V-A-K-F-K-L-G-G-G-H-G-G-H-N-G-L-K-D-I-I-S-K-L-G-N-N-P-N-F-H-R-L-R-I-G-I-G-H-P-G-D-K-N-K-V-V-G-F-V-L-G-K-P-P-V-S-E-Q-K-L-I-D-E-A-I-D-E-A-A-R-C-T-E-M-W-F-T-D-G-L-T-K-A-T-N-R-L-H-A-F-K-A-Q"} +{"text": "### FUNCTION Involved in pyrimidine catabolism Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions ### SEQUENCE -M-P-K-S-V-I-I-P-A-G-S-S-A-P-L-A-P-F-V-P-G-T-L-A-D-G-V-V-Y-V-S-G-T-L-A-F-D-Q-H-N-N-V-L-F-A-D-D-P-K-A-Q-T-R-H-V-L-E-T-I-R-K-V-I-E-T-A-G-G-T-M-A-D-V-T-F-N-S-I-F-I-T-D-W-K-N-Y-A-A-I-N-E-I-Y-A-E-F-F-P-G-D-K-P-A-R-F-Y-I-Q-C-G-L-V-K-P-D-A-L-V-E-I-A-T-I-A-H-I-A-K"} +{"text": "### FUNCTION Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products Thus, can divert a surplus of harmful intermediates into relatively harmless products and pre-empt the damage these intermediates would otherwise do Helps maintain flavin levels May act on other substrates in vivo Has no activity against GTP, nucleoside monophosphates or ADP-ribose Is Required for swarming motility ### SEQUENCE -M-P-V-R-A-Q-R-I-Q-H-V-M-Q-D-T-I-I-N-F-Y-S-T-S-D-D-Y-G-D-F-S-N-F-A-A-R-P-I-K-V-D-G-N-T-W-P-T-S-E-H-Y-F-Q-A-Q-K-F-L-D-E-K-Y-R-E-E-I-R-R-V-S-S-P-M-V-A-A-R-M-G-R-N-R-S-K-P-L-R-K-N-W-E-S-V-K-E-Q-V-M-R-K-A-L-R-A-K-F-E-Q-H-A-E-L-R-V-L-L-L-A-T-A-P-A-K-L-V-E-H-T-E-N-D-A-Y-W-G-D-G-G-N-G-K-G-K-N-R-L-G-Y-L-L-M-E-L-R-E-Q-L-A-I-E-K"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-Q-L-L-L-A-V-F-I-G-G-G-T-G-S-V-A-R-W-L-L-S-M-R-F-N-P-L-H-Q-A-I-P-L-G-T-L-A-A-N-L-I-G-A-F-I-I-G-M-G-F-A-W-F-S-R-M-T-N-I-D-P-V-W-K-V-L-I-T-T-G-F-C-G-G-L-T-T-F-S-T-F-S-A-E-V-V-F-L-L-Q-E-G-R-F-G-W-A-L-L-N-V-F-V-N-L-L-G-S-F-A-M-T-A-L-A-F-W-L-F-S-A-S-T-V-H"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-A-T-A-Q-Q-L-E-Y-L-K-N-S-I-K-S-I-Q-D-Y-P-K-P-G-I-L-F-R-D-V-T-S-L-L-E-D-P-K-A-Y-A-L-S-I-D-L-L-V-E-R-Y-K-N-A-G-I-T-K-V-V-G-T-E-A-R-G-F-L-F-G-A-P-V-A-L-G-L-G-V-G-F-V-P-V-R-K-P-G-K-L-P-R-E-T-I-S-E-N-Y-D-L-E-Y-G-T-D-Q-L-E-I-H-V-D-A-I-K-P-G-D-K-V-L-V-V-D-D-L-L-A-T-G-G-T-I-E-A-T-V-K-L-I-R-R-L-G-G-E-V-A-D-A-A-F-I-I-N-L-F-D-L-G-G-E-Q-R-L-E-K-Q-G-I-T-S-Y-S-L-V-P-F-P-G-H"} +{"text": "### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway ### SEQUENCE -M-K-N-L-I-A-E-L-L-F-K-L-A-Q-K-E-E-E-S-K-E-L-C-A-Q-V-E-A-L-E-I-I-V-T-A-M-L-R-N-M-A-Q-N-D-Q-Q-R-L-I-D-Q-V-E-G-A-L-Y-E-V-K-P-D-A-S-I-P-D-D-D-T-E-L-L-R-D-Y-V-K-K-L-L-K-H-P-C-Q"} +{"text": "### FUNCTION Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall gene cluster Acts by binding directly to DNA May also regulate the expression of genes outside the dcw cluster ### SEQUENCE -M-F-R-G-A-T-L-V-N-L-D-S-K-G-R-L-S-V-P-T-R-Y-R-E-Q-L-L-E-N-A-A-G-Q-M-V-C-T-I-D-I-H-H-P-C-L-L-L-Y-P-L-P-E-W-E-I-I-E-Q-K-L-S-R-L-L-S-M-N-P-V-E-R-R-V-Q-R-L-L-L-G-H-A-S-E-C-Q-M-D-G-A-G-R-L-L-I-A-P-V-L-R-Q-H-A-G-L-T-K-E-V-M-L-V-G-Q-F-N-K-F-E-L-W-D-E-T-T-W-H-Q-Q-V-K-E-D-I-D-A-E-Q-L-A-T-G-D-L-S-E-R-L-Q-D-L-S-L"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-K-S-N-E-T-E-R-M-E-E-S-E-E-T-H-S-S-D-I-R-S-A-S-E-S-D-H-A-S-G-S-D-H-T-E-S-A-D-E-I-P-T-A-D-A-E-Q-G-E-L-E-Q-L-E-K-L-K-D-D-L-A-R-E-R-A-A-F-H-N-F-R-M-A-R-A-K-Q-A-E-I-E-R-D-R-T-R-S-E-V-I-R-V-I-L-P-V-L-D-D-F-A-R-I-E-K-H-S-T-L-D-D-P-F-K-A-V-V-T-K-L-R-S-A-M-E-K-I-G-L-T-A-F-G-N-P-G-D-P-F-N-P-E-L-H-E-A-L-F-Q-N-P-S-P-D-V-Q-T-E-T-V-Q-D-V-I-E-A-G-Y-C-L-G-E-T-V-I-R-A-A-K-V-V-V-Q-V-P-N-G"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Y-V-R-I-V-Q-D-L-I-R-E-L-G-K-L-P-G-I-G-P-K-S-A-Q-R-I-T-F-F-I-L-Q-N-P-S-F-D-I-D-R-L-S-E-T-L-Q-S-V-R-K-Q-V-Q-F-C-K-V-C-G-N-F-S-E-E-D-E-C-V-I-C-S-D-P-R-R-D-R-G-V-I-C-V-V-E-E-P-K-D-V-V-A-I-E-K-T-R-E-F-S-G-L-Y-H-V-L-G-G-A-I-S-P-I-D-G-V-G-P-D-D-L-N-I-R-Q-L-L-Q-R-L-A-D-G-T-I-T-E-V-V-L-A-T-D-P-N-M-E-G-E-A-T-A-S-Y-I-A-R-V-I-S-A-M-R-I-R-V-S-K-L-A-S-G-L-P-V-G-S-D-L-E-Y-A-D-E-I-T-L-G-R-A-L-E-G-R-Q-Y-I-N"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-T-S-D-I-R-N-G-V-V-L-N-I-N-G-Q-L-N-T-V-I-E-F-Q-H-V-K-P-G-K-G-G-A-F-V-R-T-K-L-K-N-I-L-T-G-K-V-V-D-K-T-F-N-A-G-A-S-V-V-L-E-N-V-D-R-R-D-C-T-Y-L-Y-R-D-A-D-S-F-V-F-M-D-L-A-D-Y-D-Q-I-R-L-T-A-S-Q-V-A-S-A-A-N-Y-L-S-D-N-Q-K-V-V-I-A-T-H-N-N-A-P-L-Y-V-D-L-P-P-S-V-V-L-A-V-T-H-T-E-P-G-V-Q-A-D-R-S-T-G-G-T-K-P-A-T-L-E-T-G-Y-Q-I-Q-V-P-L-F-I-T-V-G-T-R-I-R-V-D-T-R-T-G-A-Y-I-G-K-A"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-L-S-R-E-K-V-L-E-S-I-A-Q-I-V-H-D-E-T-G-I-D-K-G-S-V-Q-L-D-K-A-F-V-D-D-L-D-I-D-S-I-S-M-M-T-I-V-V-N-A-E-E-K-Y-G-I-E-I-P-D-D-K-V-R-E-L-R-T-V-G-D-A-V-D-F-I-I-A-A-K-A"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-D-R-V-K-E-F-A-M-K-D-Q-I-R-A-H-R-M-A-G-R-I-R-H-L-I-S-R-Q-I-E-T-K-L-R-D-Q-L-G-L-V-T-I-T-E-V-Q-V-T-G-D-L-H-H-A-K-V-F-V-T-V-Y-G-T-K-D-E-A-Q-T-A-L-K-I-L-E-D-N-R-A-N-F-R-R-S-L-G-V-L-K-V-R-F-V-P-T-V-E-F-E-L-D-R-L-F-E-D-A-G-I-M-D-E-L-I-Q-R-A-R-E-S-D-K-R-I-A-A-G-A-S-G-P-I-D-N-D-A-T-A-L-M-D-K-V-V-D-Q-E-A-R-N-P-D-S-W-H-T-A-P-T-S-S-S-H-T-A-G-L-C-L-V-R-A-S-S-P-I-A-C-N-I-D-S-T-T-L-C-K-P-R-T-P-G-P-G-L"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-K-S-N-E-T-E-R-M-E-E-S-E-E-T-H-S-S-D-I-R-S-A-S-E-S-D-H-A-S-G-S-D-H-T-E-S-A-D-E-I-P-T-A-D-A-E-Q-G-E-L-E-Q-L-E-K-L-K-D-D-L-A-R-E-R-A-A-F-H-N-F-R-M-A-R-A-K-Q-A-E-I-E-R-D-R-T-R-S-E-V-I-R-V-I-L-P-V-L-D-D-F-A-R-I-E-K-H-S-T-L-D-D-P-F-K-A-V-I-T-K-L-R-S-A-M-E-K-I-G-L-T-A-F-G-N-P-G-D-P-F-N-P-E-L-H-E-A-L-F-Q-N-P-S-P-D-V-Q-T-E-T-V-Q-D-V-I-E-A-G-Y-C-L-G-E-T-V-I-R-A-A-K-V-V-V-Q-V-P-N-G"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Y-V-R-I-V-Q-D-L-I-R-E-L-G-K-L-P-G-I-G-P-K-S-A-Q-R-I-A-F-F-I-L-Q-N-P-S-F-D-I-D-R-L-S-E-T-L-Q-S-V-R-K-Q-V-Q-F-C-K-V-C-G-N-F-S-E-E-D-E-C-V-I-C-S-D-P-R-R-D-R-G-V-I-C-V-V-E-E-P-K-D-V-V-A-I-E-K-T-R-E-F-S-G-L-Y-H-V-L-G-G-A-I-S-P-I-D-G-V-G-P-D-D-L-N-I-R-Q-L-L-Q-R-L-A-D-G-T-I-T-E-V-V-L-A-T-D-P-N-M-E-G-E-A-T-A-S-Y-I-A-R-V-I-S-A-M-R-I-R-V-S-K-L-A-S-G-L-P-V-G-S-D-L-E-Y-A-D-E-I-T-L-G-R-A-L-E-G-R-Q-Y-I-N"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-D-R-V-K-E-F-A-M-K-D-Q-I-R-A-H-R-M-A-G-R-I-R-H-L-I-S-R-Q-I-E-T-K-L-R-D-Q-L-G-L-V-T-I-T-E-V-Q-V-T-G-D-L-H-H-A-K-V-F-V-T-V-Y-G-T-K-D-E-A-Q-T-A-L-K-I-L-E-D-N-R-A-N-F-R-R-S-L-G-V-L-K-V-R-F-V-P-T-V-E-F-E-L-D-R-L-F-E-D-A-G-I-M-D-E-L-I-Q-R-A-R-E-S-D-K-R-I-A-A-G-A-S-G-P-I-D-N-D-A-T-A-L-M-D-K-V-V-D-Q-E-A-R-N-P-D-S-W-H-T-A-P-T-S-S-S-H-T-A-G-L-C-L-V-R-A-S-S-P-I-A-C-N-I-D-S-T-T-L-C-K-P-R-T-P-G-P-G-L"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-L-S-R-E-K-V-L-E-S-I-A-Q-I-V-H-D-E-T-G-I-D-K-G-S-V-Q-L-D-K-A-F-V-D-D-L-D-I-D-S-I-S-M-M-T-I-V-V-N-A-E-E-K-Y-G-I-E-I-P-D-D-K-V-R-E-L-R-T-V-G-D-A-V-D-F-I-I-A-A-K-A"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-N-V-F-S-G-W-H-L-L-V-I-L-L-V-I-V-L-L-F-G-T-S-R-L-P-K-L-S-K-S-V-V-E-A-L-K-I-F-R-R-S-F-N-E-A-S-D-I-T-R-S-Q-D-G-H-P-D-S-Q-G-N-F-A-E-S-A-S-S-V-P-F-V-K-S-E-K-Q-S-E-K-R-A-S-V-T-E-A-K-K-S-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-T-S-D-I-R-N-G-V-V-L-N-I-N-G-Q-L-N-T-V-I-E-F-Q-H-V-K-P-G-K-G-G-A-F-V-R-T-K-L-K-N-I-L-T-G-K-V-V-D-K-T-F-N-A-G-A-S-V-V-L-E-N-V-D-R-R-D-C-T-Y-L-Y-R-D-A-D-S-F-V-F-M-D-L-A-D-Y-D-Q-I-R-L-T-A-S-Q-V-A-S-A-A-N-Y-L-S-D-N-Q-K-V-V-I-A-T-H-N-N-A-P-L-Y-V-D-L-P-P-S-V-V-L-A-V-T-H-T-E-P-G-V-Q-A-D-R-S-T-G-G-T-K-P-A-T-L-E-T-G-Y-Q-I-Q-V-P-L-F-I-T-V-G-T-R-I-R-V-D-T-R-T-G-A-Y-I-G-K-A"} +{"text": "### FUNCTION The phosphoenolpyruvate-dependent sugar phosphotransferase system , a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane The enzyme II UlaABC PTS system is involved in ascorbate transport ### SEQUENCE -M-K-L-H-D-S-L-A-E-N-K-S-I-R-L-Q-A-E-A-E-T-W-Q-D-A-V-K-I-G-V-D-L-L-V-A-A-D-V-V-E-P-R-Y-Y-Q-A-I-L-D-A-V-E-Q-H-G-P-Y-F-V-L-A-P-G-L-A-M-P-H-G-R-P-E-E-G-V-K-K-T-G-F-A-L-V-T-L-K-K-P-L-E-F-N-H-E-D-N-D-P-V-D-I-L-I-T-M-A-A-V-D-A-N-T-H-Q-E-V-G-I-M-Q-I-V-N-L-F-E-D-E-E-N-F-D-R-L-R-A-C-R-T-E-Q-E-V-L-D-L-I-D-R-T-N-A-A-A"} +{"text": "### FUNCTION Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion ### SEQUENCE -M-T-T-K-R-K-P-Y-V-R-P-M-T-S-T-W-W-K-K-L-P-F-Y-R-F-Y-M-L-R-E-G-T-A-V-P-A-V-W-F-S-I-E-L-I-F-A-L-F-A-L-K-N-G-P-E-A-W-A-G-F-V-D-F-L-Q-N-P-V-I-V-I-I-N-L-I-T-L-T-A-A-L-L-H-T-K-T-W-F-E-L-A-P-K-A-A-N-I-I-V-K-D-E-K-M-G-P-E-P-I-I-K-S-L-W-A-V-T-V-V-A-T-I-V-I-L-F-V-A-L-Y-W"} +{"text": "### FUNCTION Involved in resistance toward heavy metals ### SEQUENCE -M-L-D-E-K-S-S-N-T-T-S-V-V-V-L-C-T-A-P-D-E-A-T-A-Q-D-L-A-A-K-V-L-A-E-K-L-A-A-C-A-T-L-I-P-G-A-T-S-L-Y-Y-W-E-G-K-L-E-Q-E-Y-E-V-Q-M-I-L-K-T-T-V-S-H-Q-Q-A-L-L-E-C-L-K-S-H-H-P-Y-Q-T-P-E-L-L-V-L-P-V-T-H-G-D-T-D-Y-L-S-W-L-N-A-S-L-R"} +{"text": "### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway ### SEQUENCE -M-M-R-Q-S-L-Q-A-V-L-P-E-I-S-G-N-K-T-S-L-L-R-K-S-V-C-S-D-L-L-T-L-F-N-S-P-H-S-A-L-P-S-L-L-V-S-G-M-P-E-W-Q-V-H-N-P-S-D-K-H-L-Q-S-W-Y-C-R-Q-L-R-S-A-L-L-F-H-E-P-R-I-A-A-L-Q-V-N-L-K-E-A-Y-C-H-T-L-A-I-S-L-E-I-M-L-Y-H-D-D-E-P-L-T-F-D-L-V-W-D-N-G-G-W-R-S-A-T-L-E-N-V-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-Q-A-Y-V-K-L-Q-V-A-A-G-M-A-N-P-S-P-P-V-G-P-A-L-G-Q-Q-G-V-N-I-M-E-F-C-K-A-F-N-A-K-T-D-S-I-E-K-G-L-P-I-P-V-V-I-T-V-Y-A-D-R-S-F-T-F-V-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-I-K-S-G-S-G-K-P-N-K-D-K-V-G-K-I-S-R-A-Q-L-Q-Q-I-A-Q-T-K-A-A-D-M-T-G-A-D-I-E-A-M-T-R-S-I-E-G-T-A-R-S-M-G-L-V-V-E-D"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-E-F-I-T-V-A-R-P-Y-A-K-A-A-F-D-F-A-V-E-H-Q-S-V-E-R-W-Q-D-M-L-T-F-A-A-E-V-T-K-N-E-Q-M-A-E-L-L-S-G-A-L-A-P-E-T-L-A-E-S-F-I-A-V-C-G-E-Q-L-D-E-N-G-Q-N-L-I-R-V-M-A-E-N-G-R-L-N-A-L-P-D-V-L-E-Q-F-I-H-L-R-A-V-S-E-A-T-A-E-V-D-V-I-S-A-A-A-L-S-E-Q-Q-L-A-K-I-S-A-A-M-E-K-R-L-S-R-K-V-K-L-N-C-K-I-D-K-S-V-M-A-G-V-I-I-R-S-G-D-M-V-I-D-G-S-V-R-G-R-L-E-R-L-A-D-V-L-Q-S"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-D-A-V-E-K-I-G-N-R-F-D-L-V-L-V-A-A-R-R-A-R-Q-M-Q-V-G-G-K-D-P-L-V-P-E-E-N-D-K-T-T-V-I-A-L-R-E-I-E-E-G-L-I-N-N-Q-I-L-D-V-R-E-R-Q-E-Q-Q-E-L-E-A-A-E-L-Q-A-V-T-A-I-A-E-G-R-R"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-M-K-K-I-D-V-K-I-L-D-P-R-V-R-K-E-F-P-L-P-T-Y-A-T-S-G-S-A-G-L-D-L-R-A-C-L-D-D-A-V-E-L-A-P-G-D-T-T-L-V-P-T-G-L-A-I-H-I-A-D-P-S-L-A-A-M-M-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-Q-L-M-I-S-V-W-N-R-G-Q-D-S-F-T-I-Q-P-G-E-R-I-A-Q-M-I-F-V-P-V-V-Q-A-E-F-N-L-V-E-D-F-D-A-T-D-R-G-E-G-G-F-G-H-S-G-R-Q"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-I-A-K-H-R-H-A-R-S-S-A-Q-K-V-R-L-V-A-D-L-I-R-G-K-K-V-S-Q-A-L-D-I-L-T-Y-T-N-K-K-A-A-V-Q-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-D-G-A-D-I-D-D-L-K-V-T-K-I-F-V-D-E-G-P-S-M-K-R-I-M-P-R-A-K-G-R-A-D-R-I-L-K-R-T-S-H-I-T-V-V-V-S-D-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-M-H-K-G-R-N-R-G-L-A-Q-G-T-D-V-S-F-G-S-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-A-V-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-A-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-V-L-Y-E-M-G-G-V-P-E-E-L-A-R-E-A-F-K-L-A-A-A-K-L-P-I-K-T-T-F-V-T-K-T-V-M"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-D-D-E-V-I-V-L-T-G-K-D-K-G-K-R-G-K-V-K-N-V-L-S-S-G-K-V-I-I-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-L-N-Q-P-G-G-I-V-E-K-E-A-A-I-Q-V-S-N-V-A-I-F-N-A-A-T-G-K-A-D-R-V-G-F-R-F-E-D-G-K-K-V-R-F-F-K-S-N-S-E-T-I-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-K-D-E-V-V-K-K-L-M-T-E-F-N-Y-N-S-V-M-Q-V-P-R-V-E-K-I-T-L-N-M-G-V-G-E-A-I-A-D-K-K-L-L-D-N-A-A-A-D-L-A-A-F-S-R-Q-K-P-L-S-T-K-A-R-K-F-V-A-C-F-K-I-R-Q-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-E-F-F-E-R-L-I-T-I-A-V-P-R-I-R-D-F-R-G-L-S-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-Y-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-T-A-K-S-D-E-E-G-R-A-L-L-A-A-F-D-F-P-F-R-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-V-L-Q-V-L-H-I-P-D-E-R-L-R-K-V-A-K-P-V-E-E-V-N-A-E-I-Q-R-I-V-D-D-M-F-E-T-M-Y-A-E-E-G-I-G-L-A-A-T-Q-V-D-I-H-Q-R-I-I-V-I-D-V-S-E-N-R-D-E-R-L-V-L-I-N-P-E-L-L-E-K-S-G-E-T-G-I-E-E-G-C-L-S-I-P-E-Q-R-A-L-V-P-R-A-E-K-V-K-I-R-A-L-D-R-D-G-K-P-F-E-L-E-A-E-G-L-L-A-I-C-I-Q-H-E-M-D-H-L-V-G-K-L-F-M-D-Y-L-S-P-L-K-Q-Q-R-I-R-Q-K-V-E-K-L-D-R-L-K-A-R-A"} +{"text": "### FUNCTION Enhances recognition of ssrA-tagged proteins by the ClpX-ClpP protease ### SEQUENCE -M-D-L-S-Q-L-T-P-R-R-P-Y-L-L-R-A-F-Y-E-W-L-L-D-N-Q-L-T-P-L-L-V-V-D-V-T-L-P-G-V-Q-V-P-M-E-Y-A-R-D-G-Q-I-V-L-N-I-A-P-R-A-V-G-N-L-E-L-A-N-D-E-V-R-F-N-A-R-F-G-G-I-P-R-Q-V-S-V-P-L-A-A-V-L-A-I-Y-A-R-E-N-G-A-G-T-M-F-E-P-E-A-A-Y-D-E-D-T-S-I-M-N-D-E-E-A-S-A-D-N-E-T-V-M-S-V-I-D-G-D-K-P-D-H-D-D-D-T-H-P-D-D-E-P-P-Q-P-P-R-G-G-R-P-A-L-R-V-V-K"} +{"text": "### FUNCTION In vitro catalyzes the addition of water to fumarate, forming malate Cannot catalyze the reverse reaction Cannot use the cis-isomer maleate as substrate ### SEQUENCE -M-A-T-L-T-E-D-D-V-L-E-Q-L-D-A-Q-D-N-L-F-S-F-M-K-T-A-H-S-I-L-L-Q-G-I-R-Q-F-L-P-S-L-F-V-D-N-D-E-E-I-V-E-Y-A-V-K-P-L-L-A-Q-S-G-P-L-D-D-I-D-V-A-L-R-L-I-Y-A-L-G-K-M-D-K-W-L-Y-A-D-I-T-H-F-S-Q-Y-W-H-Y-L-N-E-Q-D-E-T-P-G-F-A-D-D-I-T-W-D-F-I-S-N-V-N-S-I-T-R-N-A-T-L-Y-D-A-L-K-A-M-K-F-A-D-F-A-V-W-S-E-A-R-F-S-G-M-V-K-T-A-L-T-L-A-V-T-T-T-L-K-E-L-T-P"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-D-Y-F-T-L-F-G-L-P-A-R-Y-Q-L-D-T-Q-A-L-S-L-R-F-Q-D-L-Q-R-Q-Y-H-P-D-K-F-A-S-G-S-L-A-E-Q-L-A-A-V-Q-Q-S-A-T-I-N-Q-A-W-Q-T-L-R-H-P-L-M-R-A-E-Y-L-L-S-L-H-G-F-D-L-A-S-E-Q-H-T-V-R-D-T-A-F-L-M-E-Q-L-E-L-R-E-E-L-D-E-I-E-Q-A-K-D-E-A-R-L-E-S-F-I-K-R-V-K-K-M-F-D-T-R-H-Q-L-M-V-E-Q-L-D-N-E-A-W-D-A-A-A-D-T-V-R-K-L-R-F-L-D-K-L-R-S-S-A-E-Q-L-E-E-K-L-L-D-F"} +{"text": "### FUNCTION Catalyzes the dephosphorylation of heptose of the outer membrane lipopolysaccharide core ### SEQUENCE -M-L-A-F-C-R-S-S-L-K-S-K-K-Y-F-I-I-L-L-A-L-A-A-I-A-G-L-G-T-H-A-A-W-S-S-N-G-L-P-R-I-D-N-K-T-L-A-R-L-A-Q-Q-H-P-V-V-V-L-F-R-H-A-E-R-C-D-R-S-T-N-Q-C-L-S-D-K-T-G-I-T-V-K-G-T-Q-D-A-R-E-L-G-N-A-F-S-A-D-I-S-D-F-D-L-Y-S-S-N-T-V-R-T-I-Q-S-A-T-W-F-S-A-G-K-K-L-T-V-D-K-R-L-L-Q-C-G-N-E-I-Y-S-A-I-K-D-L-Q-S-K-A-P-D-K-N-I-V-I-F-T-H-N-H-C-L-T-Y-I-A-K-N-K-R-D-A-I-F-K-P-D-Y-L-D-G-L-V-M-H-V-E-K-G-K-V-Y-L-D-G-E-F-V-N-H"} +{"text": "### FUNCTION Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD As a transcriptional regulator, acts as an anti-FlhDC factor ### SEQUENCE -M-N-N-A-P-H-L-Y-F-A-W-Q-Q-L-V-E-K-S-Q-L-M-L-R-L-A-T-E-E-Q-W-D-E-L-I-A-S-E-M-A-Y-V-N-A-V-Q-E-I-A-H-L-T-E-E-V-A-P-S-T-T-M-Q-E-Q-L-R-P-M-L-H-L-I-L-D-N-E-S-K-V-K-Q-L-L-Q-I-R-M-D-E-L-A-K-L-V-G-Q-S-S-V-Q-K-S-V-L-S-A-Y-G-D-Q-G-G-F-V-L-A-P-Q-D-N-L-F"} +{"text": "### FUNCTION Catalyzes the excretion of spermidine ### SEQUENCE -M-A-Q-F-E-W-V-H-A-A-W-L-A-L-A-I-V-L-E-I-V-A-N-V-F-L-K-F-S-D-G-F-R-R-K-I-F-G-L-L-S-L-A-A-V-L-A-A-F-S-A-L-S-Q-A-V-K-G-I-D-L-S-V-V-Y-A-L-W-G-G-F-G-I-A-A-T-L-A-A-G-W-I-L-F-G-Q-R-L-N-R-K-G-W-I-G-L-V-L-L-L-A-G-M-I-M-V-K-L-A"} +{"text": "### FUNCTION Required for growth and/or survival at acidic conditions ### SEQUENCE -M-K-K-V-L-A-L-V-V-A-A-A-M-G-L-S-S-A-A-F-A-A-E-T-A-T-T-P-A-P-T-A-T-T-T-K-A-A-P-A-K-T-T-H-H-K-K-Q-H-K-A-A-P-A-Q-K-A-Q-A-A-K-K-H-H-K-N-T-K-A-E-Q-K-A-P-E-Q-K-A-Q-A-A-K-K-H-A-G-K-H-G-H-Q-Q-P-A-K-P-A-A-Q-P-A-A"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-A-R-H-K-K-I-L-K-Q-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-A-R-Q-N-G-I-S-Y-S-K-F-I-N-G-L-K-K-A-S-V-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-V-A-F-T-T-L-V-E-K-A-K-A-A-L-A"} +{"text": "### FUNCTION May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted ### SEQUENCE -M-N-E-A-V-S-P-G-A-L-S-T-L-F-T-D-A-R-T-H-N-G-W-R-E-T-P-V-S-D-E-T-L-Q-E-L-Y-A-L-M-K-W-G-P-T-S-A-N-C-S-P-A-R-I-V-F-I-R-T-A-E-G-K-E-R-L-R-P-A-L-S-S-G-N-L-Q-K-T-L-T-A-P-V-T-A-I-V-A-W-D-S-E-F-Y-E-R-L-P-L-L-F-P-H-G-D-A-R-S-W-F-T-S-S-P-Q-L-A-E-E-T-A-F-R-N-S-S-M-Q-A-A-Y-L-I-V-A-C-R-A-L-G-L-D-T-G-P-M-S-G-F-D-R-Q-H-V-D-D-A-F-F-A-G-S-T-L-K-S-N-L-L-I-N-I-G-Y-G-D-S-S-K-L-F-A-R-L-P-R-L-S-F-E-E-A-C-G-L-L"} +{"text": "### FUNCTION Component of the SOS system and an inhibitor of cell division Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments In the presence of GTP, binds a polymerization-competent form of FtsZ in a 11 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division ### SEQUENCE -M-Y-T-S-G-Y-A-H-R-S-S-S-F-S-S-A-A-S-K-I-A-R-V-S-T-E-N-T-T-A-G-L-I-S-E-V-V-Y-R-E-D-Q-P-M-M-T-Q-L-L-L-L-P-L-L-Q-Q-L-G-Q-Q-S-R-W-Q-L-W-L-T-P-Q-Q-K-L-S-R-E-W-V-Q-A-S-G-L-P-L-T-K-V-M-Q-I-S-Q-L-S-P-C-H-T-V-E-S-M-V-R-A-L-R-T-G-N-Y-S-V-V-I-G-W-L-T-D-D-L-T-E-E-E-H-A-E-L-V-D-A-A-N-E-G-N-A-M-G-F-I-M-R-P-V-S-A-S-S-H-T-T-R-Q-L-S-G-L-K-I-H-S-N-L-Y-H"} +{"text": "### FUNCTION Acts as a global negative controlling element, employing Fe ### SEQUENCE -M-T-D-N-N-T-A-L-K-K-A-G-L-R-V-T-L-P-R-L-K-I-L-E-V-L-Q-E-P-D-N-H-H-V-S-A-E-D-L-Y-K-R-L-I-D-M-G-E-E-I-G-L-A-T-V-Y-R-V-L-N-Q-F-D-D-A-G-I-V-T-R-H-N-F-E-G-G-K-S-V-F-E-L-T-Q-Q-H-H-H-D-H-L-I-C-L-D-C-G-K-V-I-E-F-S-D-D-S-I-E-A-R-Q-G-E-I-A-A-K-H-G-I-R-L-T-N-H-S-L-Y-L-Y-G-H-C-A-E-G-D-C-R-E-D-E-H-A-H-E-G-K"} +{"text": "### FUNCTION Low-potential electron donor to a number of redox enzymes ### SEQUENCE -M-A-I-H-G-I-F-F-G-S-D-T-G-N-T-E-N-I-A-K-M-I-Q-K-Q-L-G-K-D-V-A-D-V-H-D-I-A-K-S-S-K-E-D-L-E-A-Y-D-I-L-L-L-G-I-P-T-W-Y-Y-G-E-A-Q-C-D-W-D-D-F-F-P-T-L-E-E-I-D-F-N-G-K-L-V-A-L-F-G-C-G-D-Q-E-D-Y-A-E-Y-F-C-D-A-L-G-T-I-R-D-I-I-E-P-R-G-A-T-I-D-A-D-W-P-T-A-G-Y-H-F-Q-A-S-K-G-L-A-D-D-D-H-F-V-G-L-A-I-D-E-D-R-H-P-E-L-T-A-D-R-V-E-K-W-V-K-Q-I-S-E-E-L-H-L-D-E-I-L-N-A"} +{"text": "### FUNCTION Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP ### SEQUENCE -M-T-D-N-L-P-E-V-R-E-A-Q-E-W-F-R-S-E-T-R-R-V-A-P-I-T-L-D-V-M-W-D-H-F-L-S-R-H-W-S-Q-L-S-P-D-F-P-L-Q-E-F-V-C-Y-A-R-E-Q-V-M-T-I-L-P-D-S-P-P-R-F-I-N-L-N-N-Y-L-W-S-E-Q-W-L-V-R-Y-R-D-M-D-F-I-Q-N-V-L-N-G-M-A-S-R-R-P-R-L-D-A-L-R-D-S-W-Y-D-L-D-A-H-Y-D-A-L-E-T-R-F-W-Q-F-Y-P-R-M-M-A-Q-A-S-H-K-A-L"} +{"text": "### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-T-L-P-S-G-H-P-K-S-R-L-I-K-K-F-T-A-L-G-P-Y-I-R-E-G-K-C-E-D-N-R-F-F-F-D-C-L-A-V-C-V-N-V-K-P-A-P-E-V-R-E-F-W-G-W-W-M-E-L-E-A-Q-E-S-R-F-T-Y-S-Y-Q-F-G-L-F-D-K-A-G-D-W-K-S-V-P-V-K-D-T-E-V-V-E-R-L-E-H-T-L-R-E-F-H-E-K-L-R-E-L-L-T-T-L-N-L-K-L-E-P-A-N-D-F-R-D-E-P-V-K-L-T-A"} +{"text": "### FUNCTION Overproduction of CaiE stimulates the activity of CaiB and CaiD ### SEQUENCE -M-S-Y-Y-A-F-E-G-L-I-P-V-V-H-P-T-A-F-V-H-P-S-A-V-L-I-G-D-V-I-V-G-A-G-V-Y-I-G-P-L-A-S-L-R-G-D-Y-G-R-L-I-V-Q-A-G-A-N-I-Q-D-G-C-I-M-H-G-Y-C-D-T-D-T-I-V-G-E-N-G-H-I-G-H-G-A-I-L-H-G-C-V-I-G-R-D-A-L-V-G-M-N-S-V-I-M-D-G-A-V-I-G-E-E-S-I-V-A-A-M-S-F-V-K-A-G-F-S-G-E-K-R-Q-L-L-M-G-T-P-A-R-A-V-R-S-V-S-D-D-E-L-H-W-K-R-L-N-T-K-E-Y-Q-D-L-V-G-R-C-H-A-S-L-H-E-T-Q-P-L-R-Q-M-E-E-N-R-P-R-L-Q-G-T-T-D-V-T-P-K-R"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-R-A-I-Q-S-E-K-A-R-K-I-I-A-S-R-R-S-M-M-R-P-F-I-K-K-G-D-A-A-I-E-A-G-D-K-A-A-A-Q-K-A-F-N-E-M-Q-P-I-V-D-R-Q-A-A-K-G-L-I-H-K-N-K-A-A-R-H-K-A-N-L-T-A-Q-I-N-K-L-A"} +{"text": "### FUNCTION Specific electron transport protein capable of effectively supporting cytochrome P450 MycCI activity in the biosynthesis of mycinamicin, a 16-membered macrolide antibiotic ### SEQUENCE -M-R-I-V-L-D-A-E-R-C-V-G-A-G-Q-C-E-A-T-A-P-E-L-F-T-Q-G-D-D-G-L-G-L-V-R-D-R-P-V-T-P-E-L-L-G-P-A-R-E-A-V-D-R-C-P-V-R-A-I-R-I-E-S-S-V-R-T-G-W-A-R-G-A-G"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-E-R-K-E-V-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-E-K-S-T-R-G-V-V-L-A-V-G-K-G-R-I-L-E-N-G-T-V-L-P-L-D-V-K-V-G-D-T-V-I-F-A-E-G-Y-G-T-K-T-E-K-I-D-G-K-E-V-L-V-M-S-E-N-D-I-M-A-I-V-D-L-I-A-I-V-E"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-T-I-T-D-P-S-K-L-A-Y-L-S-S-A-W-A-D-P-N-S-L-I-N-L-C-T-N-S-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-A-D-V-W-Q-P-V-P-T-L-T-S-R-F-P-A-G-A-G-H-F-R-V-Y-R-Y-E-P-I-L-E-P-L-I-T-F-L-M-G-T-F-D-T-R-N-R-I-I-E-V-R-N-P-Q-N-P-T-T-T-E-T-L-D-A-T-R-R-V-D-D-A-T-V-A-I-R-S-A-I-N-N-L-L-N-E-L-V-R-G-N-G-M-Y-N-Q-V-S-F-E-T-M-S-G-L-T-W-T-S-S"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-T-I-T-D-P-S-K-L-A-Y-L-S-S-A-W-A-D-P-N-S-L-I-N-L-C-T-N-S-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-A-D-V-W-Q-P-V-P-T-L-T-S-R-F-P-A-G-A-G-Y-F-R-V-Y-R-Y-D-P-I-L-D-P-L-I-T-F-L-M-G-T-F-D-T-R-N-R-I-I-E-V-E-N-P-Q-N-P-T-T-T-E-T-L-D-A-T-R-R-V-D-D-A-T-V-A-I-R-S-A-I-N-N-L-L-N-E-L-V-R-G-T-G-M-Y-N-Q-V-S-F-E-T-M-S-G-L-T-W-T-S-S"} +{"text": "### FUNCTION Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine proteins that have critical roles in mRNA metabolism Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions ### SEQUENCE -M-A-D-D-S-A-L-H-K-K-Y-P-F-L-N-L-L-H-T-P-P-H-R-P-P-P-L-C-P-Q-A-P-R-K-T-Q-C-K-R-R-L-E-N-E-H-E-E-S-N-S-H-L-A-T-P-C-V-W-P-T-L-D-P-W-T-V-E-T-T-T-S-S-L-T-I-T-T-S-T-K-E-G-T-T-V-T-V-Q-L-R-L"} +{"text": "### FUNCTION Plays a role in viral DNA replication ### SEQUENCE -M-A-Q-A-Q-I-D-E-Q-R-R-L-Q-D-L-Y-V-Q-L-K-K-E-I-N-D-G-E-G-V-A-W-L-F-Q-Q-K-T-Y-T-D-K-D-N-K-P-T-K-A-T-P-P-L-R-T-T-S-S-D-L-R-D-Y-W-T-K-L-E-C-H-N-C-H-E-E-Y-W-Q-L-T-T-Y-Y-C-K-E-C-R-K-C-E-H-G-K-L-R-H-T-K-K-E-C-E-Q-C-A-C-K-A-A-Q-E-T-S-A"} +{"text": "### FUNCTION Plays a role in viral DNA replication ### SEQUENCE -M-A-Q-A-Q-I-D-E-Q-R-R-L-Q-D-L-Y-V-Q-L-K-K-E-I-N-D-G-E-G-V-A-W-L-F-Q-Q-K-T-Y-T-D-K-D-N-K-P-T-K-A-T-P-P-L-R-T-T-S-S-D-L-R-L-C-D-C-N-K-Q-H-Q-H-N-Q-S-N-C-W-M-C-G-N-K-R-S-R-R-A-T"} +{"text": "### FUNCTION Potassium-selective channel essential in the virus replication cycle May be involved in preventing multiple infections ### SEQUENCE -M-L-V-F-S-K-F-L-T-R-T-E-P-F-M-I-H-L-F-I-L-A-M-F-V-M-I-Y-K-F-F-P-G-G-F-E-N-N-F-S-V-A-N-P-D-K-K-A-S-W-I-D-C-I-Y-F-G-V-T-T-H-S-T-V-G-F-G-D-I-L-P-K-T-T-G-A-K-L-C-T-I-A-H-I-V-T-V-F-F-I-V-L-T-L"} +{"text": "### FUNCTION Involved in the dimethyl sulfide degradation pathway ### SEQUENCE -M-S-T-P-L-N-V-V-A-L-S-G-G-T-S-R-P-S-R-T-L-A-L-T-E-A-I-L-A-E-L-A-E-H-L-H-I-K-P-H-L-I-E-L-G-E-I-A-R-P-L-G-S-A-L-W-R-S-E-L-P-E-A-V-E-Q-Q-L-R-L-V-E-K-A-D-L-L-V-V-T-T-P-V-Y-R-G-S-F-T-G-H-F-K-H-L-F-D-L-I-G-Q-D-A-L-V-D-T-P-V-L-L-A-A-T-G-G-S-E-R-H-A-L-V-L-D-H-Q-L-R-P-L-F-S-F-L-Q-A-L-T-L-P-I-G-V-F-A-S-Q-A-E-M-A-D-Y-R-V-S-S-A-A-L-A-A-R-I-R-L-A-A-E-R-A-V-P-L-F-G-A-H-H-A-L-R-K-S-A"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-K-K-K-Y-T-I-R-K-K-I-F-G-F-L-E-K-P-R-V-S-I-F-R-S-N-K-H-I-Y-A-Q-V-I-D-D-Y-K-G-N-T-L-I-S-A-S-S-K-K-L-L-K-F-Y-K-K-R-R-E-K-K-I-T-K-K-E-L-S-Y-K-I-G-N-L-L-G-K-I-I-K-S-Y-G-I-S-K-I-L-F-D-R-N-G-Y-I-Y-H-G-R-V-K-A-L-A-K-G-L-R-N-V-G-L-Q-F"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-P-Y-T-V-S-S-P-N-Q-L-V-Y-F-G-S-V-W-A-D-P-I-A-L-I-D-L-C-T-V-S-L-G-N-Q-F-Q-T-Q-N-A-R-T-T-V-Q-Q-Q-F-S-D-L-F-K-T-V-P-T-R-T-I-R-F-S-D-G-E-N-G-F-R-V-F-R-Y-N-S-T-L-D-P-L-I-T-A-L-L-N-S-F-D-T-R-N-R-I-I-E-T-E-N-P-A-N-P-N-T-A-E-I-A-S-A-T-Q-R-V-D-D-A-T-V-S-I-R-A-C-I-N-N-L-M-N-E-L-A-R-G-T-G-M-L-N-T-V-S-F-E-T-I-S-N-L-T-W-T-T-A-A-T-T"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-A-Y-T-V-T-S-A-N-Q-L-V-Y-L-G-S-V-W-A-D-P-L-E-L-Q-N-L-C-T-S-A-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-S-D-V-W-K-T-I-P-T-A-T-V-R-F-P-A-T-G-F-K-V-F-R-Y-N-A-V-L-D-S-L-V-S-A-L-L-G-A-F-D-T-R-N-R-I-I-E-V-E-N-P-Q-N-P-T-T-A-E-T-L-D-A-T-R-R-V-D-D-A-T-V-A-I-R-A-S-I-S-N-L-M-N-E-L-V-R-G-T-G-N-Y-N-Q-A-L-F-E-S-V-S-G-L-T-W-A-T-T-P"} +{"text": "### FUNCTION May act as a membrane anchor for the tetrachloroethene reductive dehalogenase PceA ### SEQUENCE -M-N-I-Y-D-V-L-I-W-M-A-L-G-M-I-A-L-L-I-Q-Y-G-I-W-R-Y-L-K-G-K-G-K-D-P-I-P-L-Q-I-C-G-F-L-A-N-F-F-F-I-F-A-L-A-W-G-Y-S-S-F-S-E-R-E-Y-Q-A-I-G-M-G-F-I-F-F-G-G-T-A-L-I-P-A-I-I-T-Y-R-L-A-N-H-P-A-K-K-I-R-E-S-S-D-S-I-S-A"} +{"text": "### FUNCTION A DNA-binding protein that is part of the type III plasmid partition system used to ensure correct segregation of the pBM400 plasmid Binds the plasmid origin of replication, probably cooperatively, forming a ring or short helix with external DNA ### SEQUENCE -M-S-D-Y-F-E-E-V-M-R-K-L-T-I-E-D-V-S-I-L-G-W-L-F-Q-N-E-A-N-A-V-F-K-A-I-K-K-S-S-I-A-D-E-L-E-Y-S-T-A-N-F-R-K-T-L-N-K-L-E-A-I-H-F-I-G-T-V-T-G-G-K-E-H-K-L-Y-L-T-E-Y-G-Q-Q-A-V-Q-Q-A-I-H-H-G-E-E-N-E-E-V-E-E-I"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-Q-A-R-A-R-H-K-K-V-L-K-Q-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-T-K-A-G-Q-Y-A-Y-R-A-R-R-T-K-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-S-R-Q-N-G-L-S-Y-S-R-F-I-N-G-L-K-K-A-S-I-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-A-A-F-A-V-L-V-E-K-A-K-T-A-L"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-K-E-E-F-P-S-E-K-N-L-D-K-E-E-N-T-S-K-P-K-K-A-V-K-K-E-A-A-K-G-E-E-T-K-K-N-N-E-N-Q-K-L-A-K-E-I-A-D-L-K-E-K-N-K-D-L-E-D-K-Y-L-R-S-E-A-E-I-Q-N-M-Q-N-R-Y-T-K-E-R-A-Q-L-I-K-Y-E-S-Q-S-L-A-K-D-V-L-P-A-M-D-N-L-E-R-A-L-S-V-E-A-D-D-D-V-S-K-Q-L-K-K-G-V-Q-M-T-L-D-A-L-V-K-A-M-K-D-H-G-V-V-E-I-E-A-D-G-V-K-F-D-P-T-L-H-Q-A-V-Q-T-V-A-A-E-N-D-D-Q-K-D-H-V-V-Q-V-L-Q-K-G-Y-Q-Y-K-D-R-T-L-R-P-A-M-V-V-V-A-Q"} +{"text": "### FUNCTION Inhibitor of the alkaline protease ### SEQUENCE -M-V-F-A-A-W-Y-L-K-F-A-F-F-V-A-L-A-F-S-I-I-G-G-S-M-A-S-S-L-V-L-P-H-A-S-E-L-K-G-V-W-Q-L-S-D-K-H-Q-Q-C-D-V-S-L-T-D-Q-P-L-P-E-G-S-I-W-S-L-N-G-D-N-D-C-L-A-Y-M-F-G-E-V-P-A-G-W-R-P-T-P-D-G-L-T-I-T-D-E-Q-G-S-G-L-A-F-F-A-N-E-P-D-G-W-F-A-R-F-A-D-G-R-E-L-M-M-K-P-N-K-T-N-K-K-N-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-S-K-I-V-K-L-Q-V-V-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-A-G-V-N-I-M-G-F-C-K-E-F-N-E-R-T-K-D-K-A-G-L-I-I-P-V-E-I-T-V-F-E-D-R-S-F-T-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-K-I-E-K-A-S-G-E-P-N-K-N-K-V-A-K-L-P-R-A-E-A-M-K-I-A-E-S-K-M-E-D-L-N-A-A-D-I-E-A-A-T-R-M-I-E-G-T-A-R-S-M-G-I-E-I-V-D"} +{"text": "### FUNCTION Heavy-metal-binding protein ### SEQUENCE -M-S-M-T-V-E-I-R-V-P-N-L-D-C-E-G-C-A-S-K-L-R-K-T-L-L-K-L-K-G-V-E-E-V-E-V-E-M-E-T-Q-K-V-T-A-R-G-Y-R-L-E-E-K-K-V-L-K-A-V-R-R-A-G-K-A-A-E-L-W-P-Y-R-L-G-N-S-H-F-A-S-F-Y-K-Y-P-S-Y-V-T-N-H-Y-Y-S-D-A-H-R-T-D-P-T-G-G-V-H-T-F-F-H-T-P-A-D-Y-S-V-A-V-A-G-D-E-I-A-A-S-M-F-S-D-D-N-P-H-A-C-T-I-M"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-E-G-L-T-S-E-Q-M-V-A-F-Q-E-A-F-L-L-F-D-K-N-G-D-G-C-I-T-L-E-E-L-A-A-V-T-R-S-L-G-L-E-P-T-D-Q-E-L-N-D-M-M-R-E-V-D-T-D-G-N-G-I-I-D-F-Q-E-F-L-S-L-I-A-R-K-M-K-D-G-D-G-D-E-E-L-K-E-A-F-E-V-L-D-K-D-Q-N-G-F-I-S-P-T-E-L-R-T-V-M-T-N-L-G-E-K-M-T-D-E-E-V-E-Q-M-I-R-E-A-D-T-D-G-D-G-Q-V-N-Y-D-E-F-V-I-M-M-K-N-A-E-R-K-I-S-G"} +{"text": "### FUNCTION Variant histones H2A are synthesized throughout the cell cycle and are very different from classical S-phase regulated H2A May replace conventional H2A in a subset of nucleosomes Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling ### SEQUENCE -M-A-G-K-G-G-K-G-L-L-A-A-K-T-T-A-A-K-S-A-E-K-D-K-G-K-K-A-P-V-S-R-S-S-R-A-G-L-Q-F-P-V-G-R-I-H-R-Q-L-K-Q-R-T-Q-A-N-G-R-V-G-A-T-A-A-V-Y-S-A-A-I-L-E-Y-L-T-A-E-V-L-E-L-A-G-N-A-S-K-D-L-K-V-K-R-I-T-P-R-H-L-Q-L-A-I-R-G-D-E-E-L-D-T-L-I-K-G-T-I-A-G-G-G-V-I-P-H-I-H-K-S-L-I-N-K-S-S-K-E"} +{"text": "### FUNCTION Probable transcription factor ### SEQUENCE -M-G-R-G-R-V-E-L-K-K-I-E-N-P-T-N-R-Q-V-T-F-S-K-R-R-M-G-L-L-K-K-A-N-E-L-A-I-L-C-D-A-Q-I-G-V-I-V-F-S-G-T-G-K-M-Y-E-Y-S-S-P-P-W-R-I-A-N-I-F-D-R-Y-L-K-A-P-S-T-R-F-E-E-M-D-V-Q-Q-R-I-I-Q-E-M-T-R-M-K-D-E-N-N-R-L-R-I-I-M-R-Q-Y-M-G-D-D-L-A-S-L-T-L-Q-D-V-S-N-L-E-Q-Q-I-E-F-S-L-Y-K-V-R-L-R-K-Q-Q-L-L-D-Q-Q-L-L-E-M-H-S-R-V-C-N-K-R-I-Y-R-F-S-I-L-P-Y-L-I-H-Y-I-E-I-I-K-F"} +{"text": "### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-A-Q-R-E-K-K-V-E-E-P-T-E-L-R-A-P-E-M-T-L-C-A-N-S-C-G-F-P-G-N-P-A-T-N-N-L-C-Q-N-C-F-L-A-A-S-A-S-S-S-S-S-S-A-A-A-S-P-S-T-T-S-L-P-V-F-P-V-V-E-K-P-R-Q-A-V-Q-S-S-A-A-A-A-V-A-L-V-V-E-R-P-T-A-G-P-V-E-S-S-S-K-A-S-R-S-S-S-V-N-R-C-H-S-C-R-R-R-V-G-L-T-G-F-R-C-R-C-G-E-L-Y-C-G-A-H-R-Y-S-D-R-H-D-C-S-F-D-Y-K-S-A-A-R-D-A-I-A-R-E-N-P-V-V-R-A-A-K-I-V-R-F"} +{"text": "### FUNCTION Probably acts as a transcriptional activator Binds to the GCC-box pathogenesis-related promoter element May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways ### SEQUENCE -M-E-G-S-S-S-S-M-Q-S-K-Y-K-G-V-R-K-R-K-W-G-K-W-V-S-E-I-R-L-P-N-S-R-E-R-I-W-L-G-S-Y-D-T-P-E-K-A-A-R-A-F-D-A-A-L-Y-C-L-R-G-N-N-A-K-F-N-F-P-D-N-P-P-V-I-S-G-G-R-N-L-S-R-S-E-I-R-E-A-A-A-R-F-A-N-S-A-E-D-D-S-S-G-G-A-G-Y-E-I-R-Q-E-S-A-S-T-S-M-D-V-D-S-E-F-L-S-M-L-P-T-V-G-S-G-N-F-A-S-E-F-G-L-F-P-G-F-D-D-F-S-D-E-Y-S-G-D-R-F-R-E-Q-L-S-P-T-Q-D-Y-Y-Q-L-G-E-E-T-Y-A-D-G-S-M-F-L-W-N-F"} +{"text": "### FUNCTION Transcriptional repressor that may regulate multiple aspects of plant growth and development through the regulation of BEL1-LIKE homeodomain transcription factors ### SEQUENCE -M-R-V-K-A-T-L-I-N-F-K-S-K-L-S-K-S-C-N-R-F-V-S-L-F-R-F-R-V-K-R-P-V-F-I-R-P-L-R-A-R-H-G-N-V-K-P-R-H-Q-H-H-H-S-K-K-P-I-C-S-C-L-C-F-L-N-S-S-K-N-H-K-M-S-N-A-K-H-R-S-S-S-F-S-V-N-D-D-D-Y-S-K-F-M-Q-S-P-L-T-P-A-T-A-K-K-L-F-T-S-P-I-T-T-P-Y-S-S-R-T-R-K-S-L-N-A-R-D-T-F-E-D-N-A-V-E-D-A-C-R-S-F-E-N-Y-L-I-H-L-I-V-E-E-G-K-I-D-D-L-M-D-I-E-E-L-L-F-C-W-K-N-L-K-S-P-V-F-I-E-L-V-S-R-F-Y-G-E-L-C-R-D-L-F-S-G-E"} +{"text": "### FUNCTION Actin-depolymerizing protein Severs actin filaments ### SEQUENCE -M-A-N-A-T-S-G-V-A-V-S-E-E-C-K-A-R-F-Q-E-L-R-A-G-R-A-H-R-F-V-V-F-K-I-D-D-A-M-R-Q-V-V-V-D-R-V-G-P-R-D-A-G-F-D-E-L-T-A-S-L-P-A-D-G-C-R-Y-A-V-Y-D-H-D-F-T-V-S-D-A-T-A-T-A-A-A-G-E-G-G-E-A-P-R-S-K-I-F-F-V-S-W-S-P-A-A-A-D-V-R-S-K-M-V-Y-A-S-S-N-E-G-F-K-K-E-L-D-G-V-Q-I-D-L-Q-A-T-D-P-S-E-L-T-L-D-V-L-K-D-H-T-S"} +{"text": "### FUNCTION Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism ### SEQUENCE -M-A-K-E-E-Y-V-S-R-M-L-V-M-L-I-M-I-M-P-L-V-A-Q-G-S-R-L-H-S-W-A-N-R-L-E-E-T-G-K-D-K-V-T-N-L-Q-F-Y-F-H-D-T-L-S-G-K-N-P-T-A-V-K-V-A-Q-G-T-D-T-E-K-S-P-T-L-F-G-A-V-F-M-V-D-D-A-L-T-E-T-A-D-P-K-S-K-L-V-G-R-A-Q-G-L-Y-G-S-S-C-K-E-E-V-G-L-I-M-A-M-S-F-C-F-E-D-G-P-Y-K-D-S-T-I-S-M-I-G-K-N-S-A-M-N-P-I-R-E-M-P-I-V-G-G-T-G-M-F-R-M-A-R-G-Y-A-I-A-R-T-N-W-F-D-P-K-T-G-D-A-I-V-G-Y-N-V-T-I-M-H"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-D-A-K-Q-S-V-A-A-A-K-P-S-L-A-K-K-T-A-S-A-S-F-R-L-R-N-G-S-L-N-A-V-R-L-R-R-V-F-D-L-F-D-R-N-G-D-G-E-I-T-V-D-E-L-A-Q-A-L-D-A-L-G-L-V-A-D-R-D-G-L-A-A-T-V-S-A-Y-V-P-E-G-A-A-G-L-R-F-E-D-F-D-A-L-H-R-A-L-G-D-A-L-F-G-S-L-D-G-A-A-A-A-G-E-P-G-G-G-G-G-D-E-E-E-E-M-R-E-A-F-K-V-F-D-V-D-G-D-G-F-I-S-A-S-E-L-Q-E-V-L-K-K-L-G-L-P-E-A-G-S-L-A-T-V-R-E-M-I-C-N-V-D-R-N-S-D-G-R-V-D-F-G-E-F-K-S-M-M-Q-G-I-T-V-W-G-P"} +{"text": "### FUNCTION Putative zinc finger that may be involved in programmed cell death and defense response ### SEQUENCE -M-Q-D-Q-L-I-C-S-G-C-R-R-V-V-Q-Y-R-R-G-V-A-G-V-C-C-P-G-C-N-T-L-T-A-V-N-P-S-A-V-A-D-M-S-E-L-I-C-S-G-C-P-T-L-L-F-Y-N-R-G-A-S-N-I-R-C-P-S-C-N-R-L-N-S-T-R-S-A-N-Q-I-A-H-L-T-C-G-Q-C-R-T-T-L-M-H-P-P-G-A-S-T-V-Q-C-A-T-C-R-Y-V-N-H-V-R-D-A-R-P-Q-T-V-L-V-E-N-P-K-T-L-D-D-K-G-K-L-V-S-N-V-V-V-G-V-T-S-W-K-R"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-D-H-L-M-C-D-I-E-G-N-H-L-S-S-A-A-I-L-G-H-D-G-T-V-W-A-Q-S-P-S-F-P-Q-L-K-P-E-E-V-S-A-I-M-K-D-F-N-E-P-G-S-L-A-P-T-G-L-H-L-G-G-T-K-Y-M-V-I-Q-G-E-P-G-D-V-I-R-G-K-K-G-P-G-G-V-T-I-K-K-T-N-Q-A-L-I-I-G-I-Y-G-E-P-M-T-P-G-Q-C-N-M-V-V-E-R-I-G-D-Y-L-V-E-Q-G-M"} +{"text": "### FUNCTION Involved in regulation of actin and microtubule organization Part of a WAVE complex that activates the Arp2/3 complex ### SEQUENCE -M-A-R-A-G-G-H-G-M-G-N-P-V-N-V-G-I-A-V-Q-A-D-W-E-N-R-E-F-I-S-N-I-S-L-N-V-R-R-L-F-D-F-L-L-R-F-E-A-T-T-K-S-K-L-A-S-L-N-E-K-L-D-I-L-E-R-K-L-E-V-L-E-V-Q-V-S-S-A-T-T-N-P-S-V-F-N"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-G-G-K-E-L-S-E-E-Q-V-A-S-M-R-E-A-F-S-L-F-D-T-D-G-D-G-R-I-A-P-S-E-L-G-V-L-M-R-S-L-G-G-N-P-T-Q-A-Q-L-R-D-I-A-A-Q-E-K-L-T-A-P-F-D-F-P-R-F-L-D-L-M-R-A-H-L-R-P-E-P-F-D-R-P-L-R-D-A-F-R-V-L-D-K-D-A-S-G-T-V-S-V-A-D-L-R-H-V-L-T-S-I-G-E-K-L-E-P-H-E-F-D-E-W-I-R-E-V-D-V-A-P-D-G-T-I-R-Y-D-D-F-I-R-R-I-V-A-K"} +{"text": "### FUNCTION May only reduce GSH-thiol disulfides, but not protein disulfides ### SEQUENCE -M-A-A-T-A-A-A-S-V-A-A-I-S-P-L-P-G-A-S-L-P-R-P-V-S-A-R-V-P-L-L-P-R-A-S-P-P-T-W-R-L-S-V-G-S-A-R-A-R-S-T-R-C-L-A-A-A-G-G-G-G-L-A-P-E-M-R-A-T-L-D-K-V-V-G-S-H-K-V-V-L-F-M-K-G-T-K-D-F-P-Q-C-G-F-S-H-T-V-V-Q-I-L-R-S-L-D-V-P-F-E-T-L-D-V-L-A-N-E-A-L-R-Q-G-L-K-E-Y-S-S-W-P-T-F-P-Q-L-Y-I-D-G-E-F-F-G-G-C-D-I-T-V-D-A-Y-K-S-G-E-L-Q-E-T-L-E-K-A-M-L-S"} +{"text": "### FUNCTION Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates Responsible for the transcription of early, intermediate and late genes DNA-dependent RNA polymerase associates with the early transcription factor , itself composed of OPG118 and OPG133, thereby allowing the early genes transcription Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase ### SEQUENCE -M-M-N-Q-Y-N-V-T-Y-L-S-K-I-L-C-L-K-T-E-I-L-Y-K-P-F-S-I-I-N-R-S-I-V-N-Q-Y-N-I-D-V-K-Y-D-D-I-T-S-I-V-K-I-R-H-K-T-E-N-T-I-L-V-F-Q-I-F-N-E-S-N-V-K-Y-S-P-I-E-Y-D-Y-G-D-P-I-I-I-T-S-N-L-Q-H-G-H-N-R-I-P-I-N-M-L-Y-I-D-V-V-E-S-D-M-F-P-T-F-S-R-L-D-S-E-T-I-K-I-I-T-S-I-L-Q-S-D-N-K-K-E-Q-S-I-K-L-P-K-V-S-E-N-E-L-S-V-K-I-L-Y-H-K-D-Y-P-L-K-Y-V-R-Y-Y-K-N-N-M-V-T-G-I-E-V-I-D-R-S-V-A-I-T-S"} +{"text": "### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-A-Q-E-S-W-K-K-E-A-E-E-T-G-V-H-T-P-E-A-P-I-L-C-V-N-N-C-G-F-F-G-S-R-M-T-E-N-M-C-S-K-C-Y-R-D-T-V-K-A-K-T-V-A-T-V-V-E-K-K-P-L-A-S-L-S-S-T-P-L-V-T-E-V-T-D-G-G-S-G-S-V-A-D-G-K-Q-V-M-E-E-D-T-P-K-P-P-S-N-R-C-L-S-C-R-K-K-V-G-L-T-G-F-K-C-R-C-G-G-T-F-C-S-M-H-R-Y-A-D-S-H-K-C-T-F-D-Y-K-Q-V-G-R-E-Q-I-A-K-Q-N-P-L-V-K-A-D-K-I-T-K-I"} +{"text": "### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-A-S-M-K-R-K-C-P-D-D-E-T-A-C-G-S-G-A-G-A-A-M-C-V-T-G-C-G-F-F-G-S-E-A-T-N-N-M-C-S-R-C-Y-R-E-H-S-A-D-N-D-A-V-E-E-A-A-A-A-N-S-D-L-E-L-V-G-V-A-E-T-T-T-K-K-A-R-M-S-A-V-V-P-V-A-V-A-S-S-S-S-A-A-A-E-Q-P-A-A-K-A-A-T-A-P-N-R-C-A-A-C-R-K-K-V-G-L-T-G-F-K-C-R-C-G-G-N-F-C-G-G-H-R-H-A-D-A-H-G-C-G-F-D-Y-K-S-A-G-K-E-Q-I-A-K-Q-N-P-L-V-V-A-D-K-L-A-T-R-I"} +{"text": "### FUNCTION Constituent of viral factories Binds to ssRNA and dsRNA ### SEQUENCE -M-S-G-T-L-P-L-A-M-T-A-S-E-S-F-V-G-M-Q-V-L-A-Q-D-K-E-V-K-A-T-F-I-A-L-D-R-K-L-P-A-N-L-K-V-P-Y-M-K-N-A-K-Y-R-T-C-I-C-P-S-S-N-H-L-V-D-D-C-V-C-E-D-V-I-I-A-Y-T-A-H-R-N-N-A-V-A-A-L-L-Y-S-D-G-N-V-I-H-R-S-G-T-L-K-P-K-S-Q-N-R-F-D-L-R-G-F-L-T-S-V-N-P-G-E-S-S-K-A-E-A-G-T-S-K-S-T-Q-K-A-Y-D-R-K-D-K-S-P-S-K-G-K-N-S-K-K-G-G-K-K-S-S-S-E-R-K-R-K-E-Y-S-S-N-S-E-T-D-L-S-S-D-S-D-A-N-T-R-K-S-K-R-K"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-Q-D-V-K-T-Y-L-S-T-A-P-V-L-A-T-L-W-F-G-F-L-A-G-L-L-I-E-I-N-R-S-F-S-D-A-L-V-L-P-F-F"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-A-Q-P-N-P-N-K-Q-S-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-I-V-N-I-A-W-A-A-L-M-V-V-S-T-S-S-L-S-P-V-A-W-G-R-S-G-L"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-L-E-I-I-A-Q-L-T-V-L-A-L-I-I-A-S-G-P-L-V-I-A-L-L-A-A-R-K-G-N-L"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-C-L-L-V-S-F-T-G-Y-A-P-Y-T-A-S-G-Q-P-S-N-E-L-R-D-L-F-E-E-H-E-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-G-T-L-G-I-I-F-F-A-I-F-F-R-D-P-P-K-V-P-S-K-G-V-P-S-K-G-K-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-I-P-T-A-F-L-L-I-L-Y-V-Q-T-A-S-Q-G-S"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-N-W-E-S-E-W-F-R-I-E-L-I-R-G-S-R-R-I-S-N-F-F-W-A-F-I-L-L-S-G-A-L-G-F-L-S-V-G-L-S-S-Y-F-G-K-D-L-I-S-F-L-S-Y-E-Q-I-V-F-I-P-Q-G-I-V-M-C-F-Y-G-I-A-G-S-A-F-S-L-Y-L-W-G-T-I-F-W-N-I-G-S-G-Y-N-K-F-D-K-G-K-G-I-V-C-I-Y-R-W-G-F-P-G-K-N-R-R-I-R-I-E-F-S-M-K-D-I-E-A-I-G-M-E-V-Q-E-G-F-Y-P-R-R-T-L-R-L-K-I-K-G-Q-Q-D-V-P-L-T-Y-I-G-E-N-L-T-L-R-E-I-E-E-E-A-A-E-L-A-R-F-L-Q-I-S-I-E-G-F"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-L-L-K-K-G-P-F-V-A-Y-H-L-L-E-K-I-E-D-L-N-I-K-R-E-K-K-I-I-V-T-W-S-R-A-S-T-I-V-P-T-M-I-G-H-T-I-A-V-Y-N-G-Q-E-H-L-P-I-Y-I-T-D-R-M-V-G-H-K-L-G-E-F-A-L-T-R-V-F-K-G-H-A-K-S-D-K-K-S-R-R"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-Q-K-N-D-N-F-I-D-K-T-F-T-I-I-A-D-I-L-L-Q-I-I-P-T-T-Q-R-E-K-E-A-F-T-H-Y-R-D-G-M-S-A-Q-S-E-G-E-Y-A-E-A-L-Q-N-Y-Y-E-A-M-R-L-E-I-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-E-H-A-K-A-L-E-Y-Y-F-Q-A-L-E-R-N-S-S-L-P-Q-A-L-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-E-E-G-D-P-E-T-C-E-V-W-F-D-Q-A-A-D-Y-W-K-K-A-I-S-L-A-P-S-N-Y-I-E-A-Q-N-W-L-R-I-T-G-R-S-K-I-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-E-K-Q-N-L-I-D-M-E-G-V-V-T-E-S-L-P-N-A-M-F-R-V-C-L-D-N-G-C-Q-V-L-T-H-I-S-G-K-I-R-R-N-Y-I-R-I-L-P-G-D-R-V-K-V-E-L-S-P-Y-D-L-T-K-G-R-I-T-Y-R-L-R-T-K-S-S-N-P"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-N-T-T-G-R-I-P-L-W-L-I-G-T-I-A-G-I-L-V-I-G-L-V-G-I-F-F-Y-G-S-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-T-A-S-Y-L-P-S-I-L-V-P-L-V-G-L-V-F-P-A-I-T-L-A-S-L-F-I-Y-I-E-Q-D-E-I-V"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-L-F-V-Y-T-V-V-I-F-F-V-S-L-F-V-F-G-F-L-S-N-D-P-K-R-N-P-G-R-K-E"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-N-Q-Q-L-I-R-K-A-R-Q-R-L-E-S-G-T-K-S-P-A-L-R-G-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-K-F-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-A-V-G-V-K-D-R-K-K-G-R-S-S-A-L-Q-S-I-V-A-T-R-I-I-A-T-I-P-Y-Q-L-F"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-S-K-R-G-P-F-V-A-N-H-L-I-R-E-I-R-N-L-N-I-Q-K-K-R-K-L-I-T-T-W-S-R-A-S-A-I-V-P-I-M-I-G-H-T-I-A-V-H-N-G-R-E-H-L-P-I-Y-V-T-D-R-M-V-G-H-K-L-G-E-F-V-P-T-R-N-F-R-G-H-A-K-S-D-K-G-S-R-R"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-K-Q-N-L-I-D-M-E-G-T-V-T-E-S-L-P-N-A-T-F-R-A-C-L-D-N-G-C-Q-V-L-T-H-I-S-G-R-M-R-R-S-Y-I-R-I-L-P-G-D-R-V-R-V-E-L-S-P-Y-D-L-T-K-G-R-I-I-Y-R-L-R-S-R-H-T-N-N-S-Q"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-A-T-E-T-A-T-L-V-T-T-F-L-S-R-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-K-P-S-K-E-L-R-D-P-F-E-E-H-E-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-A-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-N-R-G-K"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-Q-H-V-K-I-Y-L-S-T-A-P-V-V-A-T-I-W-F-G-L-L-A-G-L-L-I-E-I-N-R-F-F-P-D-A-L-L-F-P-F-P"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-P-N-P-N-K-Q-S-V-E-P-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-T-N-T-T-G-R-V-P-L-W-L-V-G-T-V-A-G-T-L-V-I-G-L-L-G-V-F-F-Y-G-A-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-N-S-R-P-T-W-I-Q-V-E-F-I-R-G-S-R-T-F-V-N-L-C-W-A-C-I-L-V-C-G-A-T-G-F-L-L-V-G-F-S-S-C-I-G-K-D-L-I-P-I-L-S-S-K-Q-I-A-F-I-P-Q-G-L-V-M-C-F-Y-G-I-A-G-L-F-L-G-L-Y-L-C-C-T-V-F-W-N-V-G-S-G-Y-N-Y-F-D-K-R-E-G-I-S-S-I-F-R-W-G-F-P-G-K-N-R-R-I-H-I-R-L-I-L-G-D-I-E-A-V-G-L-R-S-Q-E-G-L-F-P-S-R-I-L-Y-L-K-V-R-G-R-Q-S-I-P-L-T-R-I-G-E-N-S-T-P-E-Y-M-E-E-K-A-A-E-L-A-R-F-L-R-I-S-I-E-G-F"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-T-A-S-Y-L-P-S-I-L-V-P-L-V-G-I-L-L-P-A-V-T-M-A-S-L-F-L-Y-I-E-R-D-E-I-L"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-Q-R-N-D-N-F-I-D-K-T-F-T-I-L-A-D-I-L-I-R-I-L-P-T-T-K-R-E-R-E-A-F-I-Y-Y-R-D-G-M-S-A-Q-S-E-G-E-Y-A-E-A-L-G-S-Y-Y-K-A-M-R-L-E-I-D-S-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-N-H-A-K-A-L-E-Y-Y-F-Q-A-L-E-R-N-S-F-L-P-Q-A-F-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-Y-Q-G-D-L-E-I-S-E-A-W-F-D-Q-A-A-E-Y-W-R-R-A-I-A-L-S-P-D-N-Y-A-E-A-Q-N-W-L-K-I-T-G-R-F-S-P-S-H-R-W-E-S-W-N-N-S-T-R-V-A"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -M-T-T-A-F-Q-F-A-L-F-A-L-I-A-T-S-F-L-L-V-V-G-V-P-V-A-F-A-S-P-G-G-W-S-D-N-K-N-I-V-F-S-G-A-S-L-W-I-G-L-V-F-L-V-G-I-P-N-S-F-I-S"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-V-A-T-A-L-F-I-L-I-P-T-A-F-L-L-I-L-Y-I-Q-T-A-A-Q-N-N-G"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-L-E-I-I-T-Q-L-V-V-L-T-L-V-A-A-S-G-P-L-V-I-A-L-L-A-I-R-K-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-L-F-V-Y-A-V-V-I-F-F-V-S-L-F-V-F-G-F-L-S-N-D-P-G-R-N-P-G-R-K-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-T-V-S-Y-S-I-Y-L-E-N-S-L-H-F-G-D-A-L-L-A-K-L-P-E-A-Y-A-I-F-D-P-I-V-D-V-M-P-V-I-P-V-F-F-L-L-L-A-F-V-W-Q-A-A-V-S-F-R"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-I-F-V-Y-T-C-V-I-F-F-S-S-L-F-I-F-G-F-L-S-N-D-P-S-R-N-P-N-R-K-D-L-E"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II ### SEQUENCE -M-W-I-S-Y-L-G-F-L-I-F-Y-F-I-L-A-A-A-S-Y-K-I-L-K-R-I-K-W-I"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-S-I-Q-R-E-S-I-I-G-S-R-R-W-S-N-M-I-W-C-A-I-L-V-T-A-G-S-G-F-W-F-N-G-M-Q-S-E-L-A-L-Q-G-A-I-M-C-F-Y-G-S-V-A-V-T-L-S-V-Y-L-F-L-T-I-W-W-D-V-G-G-G-Y-N-E-Y-D-T-E-N-K-S-I-T-I-W-R-R-G-F-G-N-K-T-I-F-L-K-Y-T-R-D-Q-M-Q-A-L-K-V-V-V-K-D-G-L-N-P-K-R-E-I-Y-L-C-T-T-T-G-A-Q-I-P-L-T-A-V-G-E-P-M-P-L-A-E-L-E-Q-K-A-T-Q-L-A-Q-W-L-N-L-S-L-V-G-M-R-A"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-S-G-P-N-P-N-K-Q-P-V-E-L-N-R-T-S-L-Y-W-G-L-L-C-I-F-V-L-A-I-L-F-S-S-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-S-T-G-R-I-P-L-W-L-V-A-T-I-G-G-I-A-V-L-T-V-L-G-L-F-F-Y-G-S-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-Q-K-I-V-E-P-Y-A-Q-A-L-F-R-L-K-D-D-I-D-L-T-P-L-W-E-M-A-R-D-S-K-F-M-Q-L-L-M-N-P-S-I-P-K-E-K-K-W-Q-L-F-Q-P-F-D-K-L-V-Q-S-W-L-E-V-I-W-K-K-K-R-M-N-L-L-A-E-I-C-A-S-Y-L-E-L-R-K-K-K-E-G-I-V-T-V-F-V-T-S-A-T-P-L-T-D-T-Q-T-Q-Q-L-E-V-Q-L-T-R-M-C-Q-A-K-H-L-Q-C-E-Y-Q-V-D-A-Q-L-L-A-G-L-K-I-Q-M-N-G-Q-L-I-D-T-S-W-Q-T-Q-L-K-Q-L-M-K-S-L-W"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-H-T-L-L-E-T-L-L-E-S-N-V-I-N-I-A-I-L-V-V-I-L-I-R-F-A-R-Q-V-V-G-E-I-L-V-Q-R-Q-Q-Q-V-K-E-A-L-E-E-A-S-N-R-L-K-L-A-E-Q-Q-L-K-T-A-Q-E-E-W-S-Q-T-Q-E-Q-I-N-Q-I-E-E-E-A-N-Q-T-A-Q-V-V-K-E-Y-W-L-K-Q-A-N-E-A-I-A-Q-L-K-T-K-T-Q-Q-S-L-S-Q-A-S-R-Q-V-A-K-Q-I-R-Q-T-L-I-E-L-A-I-E-K-V-K-Q-T-P-I-D-G-S-Q-I-L-D-R-H-I-S-L-L-S-Y-H-E-A-K-N-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-T-G-L-F-D-F-N-G-T-L-P-V-M-G-L-Q-V-V-L-L-S-W-L-L-E-Q-I-L-Y-S-P-I-Q-G-V-I-Q-K-R-Q-N-K-I-Q-Q-E-L-Q-L-A-A-D-Q-L-Q-K-A-Q-Q-L-T-Q-E-Y-Q-T-Q-L-Q-K-A-R-E-K-A-R-E-R-I-R-Q-V-Q-Q-E-A-Q-T-M-M-E-D-Q-L-K-Q-A-Q-Q-Q-M-T-Q-L-F-N-E-A-M-Q-Q-L-E-Q-Q-K-Q-Q-A-L-M-N-L-S-N-Q-V-D-E-V-A-K-F-I-L-S-K-L-M-K-Q"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-S-I-K-R-I-R-I-S-Q-R-N-R-L-R-N-Q-A-I-K-S-H-I-K-W-L-M-K-H-A-T-K-D-E-V-E-S-A-I-D-K-A-V-N-K-G-V-I-H-R-N-K-A-V-R-M-K-S-K-Y-E-R-S-H-S-R-S-T-Q"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-N-L-K-K-Y-L-S-T-A-P-V-V-A-T-L-W-L-F-L-T-A-G-I-L-I-E-L-N-R-F-F-P-D-S-L-F-Y"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-S-R-S-Q-K-N-D-N-F-I-D-K-T-F-T-I-L-A-D-V-L-V-K-L-L-P-T-S-Q-N-A-K-K-A-F-S-Y-Y-R-E-G-M-A-A-Q-A-E-G-E-Y-A-Q-A-L-E-S-Y-Y-H-A-L-E-F-E-E-D-V-I-D-R-S-Y-I-I-Y-N-I-G-L-I-Y-A-S-N-G-E-D-E-Q-A-L-E-Y-Y-H-Q-A-L-E-L-N-P-R-L-V-Q-A-L-N-N-I-A-V-I-Y-H-K-Q-G-M-T-Y-Q-D-E-Q-L-L-Q-K-A-A-A-Y-W-R-K-A-I-Q-L-A-P-G-Q-Y-L-E-A-Q-N-W-L-K-N-M-V"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-K-M-K-I-I-T-P-D-G-Y-V-W-D-R-E-I-E-E-V-I-L-P-S-S-T-G-Q-L-G-I-L-A-H-H-A-P-L-L-T-A-L-D-I-G-V-M-R-A-K-T-A-Q-G-W-V-A-L-V-L-F-G-G-F-A-E-V-L-N-N-Q-I-T-I-L-V-N-G-A-Q-E-A-H-E-I-D-L-Q-H-A-Q-Q-E-E-A-K-A-L-E-Q-L-Q-Q-A-A-T-P-T-A-Q-I-E-A-R-Q-N-L-A-K-W-R-A-R-V-Q-A-V-S-F-Q-I"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-L-Q-Q-L-I-R-F-G-R-Q-Q-V-M-V-R-P-K-S-A-A-L-K-R-C-P-Q-R-R-G-V-C-V-K-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-K-L-T-S-G-Y-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-I-R-G-A-L-D-T-A-G-V-K-N-R-V-R-S-R-S-K-Y-G-V-K-K-A"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-N-I-H-P-K-W-Y-K-H-S-I-V-Y-G-N-G-Q-Q-I-L-T-V-G-S-T-K-P-E-L-H-V-E-V-W-S-S-I-H-P-F-Y-T-G-S-Q-K-Q-L-D-T-E-G-R-I-E-K-F-M-R-K-Y-G-M-K"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-Q-N-M-N-E-Q-Q-E-Q-W-Q-E-R-V-I-Q-I-R-R-V-A-K-V-V-K-G-G-K-K-L-S-F-R-V-L-V-V-V-G-N-L-N-G-C-V-G-V-G-M-G-K-A-A-D-V-M-S-A-V-T-K-A-V-V-D-A-K-K-Q-L-I-N-I-T-L-T-P-T-N-S-I-V-H-A-S-Q-G-R-F-S-A-A-V-V-F-L-K-P-A-A-S-G-S-G-V-I-A-G-G-A-V-R-S-V-M-E-L-A-G-I-Q-N-V-L-S-K-Q-L-G-G-S-N-P-L-N-N-A-K-A-A-L-L-A-L-K-S-S-S-A-N-A-R"} +{"text": "### FUNCTION Binds 5S rRNA, forms part of the central protuberance of the 50S subunit ### SEQUENCE -M-L-M-N-R-F-V-L-K-R-V-R-Q-G-K-P-L-N-K-P-R-L-S-I-F-C-S-H-K-H-I-Y-A-Q-I-I-D-D-M-V-G-R-T-L-V-S-A-S-T-Y-H-Y-K-Q-G-W-H-S-T-M-K-D-A-Q-E-V-G-Q-K-L-A-Q-Q-A-L-E-K-G-I-Q-Q-V-V-L-D-R-G-S-Y-R-Y-H-G-K-I-R-A-L-A-E-A-A-R-K-E-G-L-K-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-D-T-L-S-Q-M-L-T-K-I-R-N-A-Q-M-A-R-H-R-W-V-L-V-P-A-S-R-M-N-W-N-V-A-Q-V-L-R-E-E-G-L-I-A-Q-V-Q-P-A-D-L-H-L-R-I-Q-L-K-P-K-R-I-Q-R-I-W-R-V-S-K-P-G-L-R-I-Y-S-S-Y-K-N-M-P-K-V-L-G-M-L-I-I-S-T-S-K-G-V-M-T-H-Q-K-A-K-Q-M-Q-V-G-G-E-I-L-C-G-V-Y"} +{"text": "### FUNCTION Binds 5S rRNA, forms part of the central protuberance of the 50S subunit ### SEQUENCE -M-E-R-I-N-T-T-F-Y-K-T-K-V-I-P-Q-L-Q-Q-K-Y-S-Y-S-N-V-H-Q-I-P-K-L-R-S-I-H-L-N-R-C-L-G-A-V-S-Q-K-I-F-Q-K-S-S-E-E-I-A-M-I-S-G-Q-R-P-K-I-T-Y-A-K-K-A-I-A-G-F-Q-I-R-K-G-M-P-I-G-M-T-V-T-L-R-R-E-R-M-Y-D-F-L-T-K-F-I-H-L-I-L-P-R-L-K-D-F-R-G-L-N-P-T-S-F-D-G-N-G-N-Y-H-M-G-L-P-D-Q-L-A-F-P-E-I-D-Y-D-Q-I-D-Q-Y-R-G-M-D-I-S-I-I-T-T-A-K-T-D-E-E-A-K-F-L-L-E-A-L-G-M-R-F-Q"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-N-T-I-K-K-G-N-Q-V-L-V-L-S-G-N-S-K-G-Q-I-G-E-V-L-V-I-D-R-K-R-K-Q-L-V-V-K-G-I-N-Q-K-T-K-H-M-K-P-K-R-Q-G-E-V-G-Q-I-I-R-R-E-Y-P-I-H-M-S-Q-V-R-L-W-N-G"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-V-Q-T-R-L-K-V-A-D-N-T-G-A-K-E-V-M-C-I-R-V-L-K-A-S-T-A-T-L-G-D-V-I-I-V-V-V-K-E-A-L-P-N-M-M-V-K-K-S-Q-I-F-R-A-V-V-V-R-T-K-Q-A-V-R-R-A-N-G-M-H-I-R-F-D-E-N-A-V-V-L-I-D-Q-E-N-N-P-K-G-T-R-V-F-G-P-I-A-R-E-L-R-E-A-N-F-M-K-I-V-S-L-A-P-E-V-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-K-K-L-L-G-L-V-V-S-C-R-M-Q-K-T-V-I-V-E-V-K-T-Q-V-K-H-A-L-Y-G-K-R-I-M-K-K-K-R-Y-A-V-H-D-P-E-K-K-A-S-L-G-E-L-I-W-I-R-T-C-R-P-I-S-K-T-K-K-W-I-Y-D-S-S-A-N-A-S-Q-S-S-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-V-K-K-G-A-Y-V-H-V-R-L-L-K-K-I-E-R-L-N-Q-K-G-E-K-Q-I-I-K-T-W-A-R-S-S-T-I-V-P-A-M-V-G-H-T-L-A-V-Y-N-G-K-T-H-I-P-V-F-I-T-D-A-L-V-G-H-K-L-G-E-F-A-P-T-R-N-F-R-S-H-V-K-G-D-R-K-I-R-K-S-I"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-I-K-R-G-N-V-A-R-K-R-R-Q-K-I-L-K-A-A-K-G-F-Y-A-C-T-T-F-R-A-A-N-E-R-V-M-K-S-W-K-A-S-Y-R-G-R-K-L-R-K-R-D-F-R-R-L-W-I-T-R-L-N-A-I-L-P-Y-K-Y-S-K-F-V-H-Q-L-K-Q-N-Q-I-A-L-N-R-K-M-L-Y-Q-L-S-C-L-D-Q-K-G-F-E-Q-L-Y-G-L-S-L-T-R-N-H-L-I-C"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-H-L-D-L-I-S-I-T-W-G-C-L-M-A-T-F-T-A-S-L-A-L-V-I-W-A-R-N-G-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-N-E-I-V-A-L-M-I-I-C-P-L-M-V-M-V-G-L-G-M-G-F-A-L-L-W-L-Q-Q-Q-A"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -M-S-I-I-L-Q-I-L-V-V-A-L-I-V-Y-S-F-V-L-I-V-A-V-P-I-T-L-S-T-A-S-G-W-S-K-S-K-S-S-I-V-T-A-S-I-G-W-V-G-M-V-L-L-T-G-V-L-N-S-F-V-S"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-N-M-L-I-A-Q-L-P-E-T-Y-S-I-F-A-P-V-I-D-I-L-P-V-I-P-I-L-F-F-L-L-A-F-V-W-Q-A-S-V-G-F-R"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-V-E-I-L-L-S-G-I-V-L-G-L-I-P-I-T-I-L-G-L-L-M-A-A-Y-F-Q-Y-Q-R-S-K-A-A-S"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-K-S-S-V-K-E-R-E-K-K-R-E-Q-L-I-K-R-Y-E-K-K-R-K-E-I-K-Q-Q-I-I-E-A-S-T-L-K-Q-K-W-Q-A-Y-E-K-L-S-Q-L-P-K-D-S-S-P-V-R-Q-R-R-R-C-W-L-T-G-R-S-R-G-V-Y-R-Y-F-G-L-C-R-H-M-V-R-K-M-A-H-E-G-L-L-A-G-V-T-K-S-S-W"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-T-E-Q-Q-I-L-D-K-V-Q-S-I-V-S-E-Q-L-G-V-E-R-S-Q-I-S-P-N-A-S-F-T-H-D-L-G-A-D-S-L-D-N-V-E-L-V-M-A-M-E-E-E-F-D-L-E-I-P-D-S-A-A-E-Q-I-T-T-I-Q-Q-A-V-D-Y-I-L-Q-H-K-K-S-L-S-Q-N-N-L-S-Q-N-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-L-R-T-R-L-G-E-I-L-R-P-L-N-S-Q-Y-G-K-V-A-P-G-W-G-T-T-P-I-M-G-V-F-M-V-L-F-L-L-F-L-V-I-I-L-Q-I-Y-N-S-S-L-L-L-N-D-V-Q-V-D-W-M-G"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-Q-N-A-T-L-I-S-V-F-V-A-S-L-V-I-G-I-T-A-Y-A-I-F-V-S-F-G-P-S-A-R-N-L-R-D-P-F-E-E-H-E-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-V-F-L-L-I-G-T-L-M-I-I-F-F-A-I-F-F-R-E-P-P-R-I-A-K-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-T-K-I-N-S-L-L-E-E-I-K-S-L-T-L-L-E-A-A-E-L-V-K-Q-M-E-T-T-F-G-I-D-A-S-A-V-A-T-A-A-P-A-V-Q-V-E-T-K-K-E-E-K-T-E-F-A-L-V-L-S-Q-V-P-A-D-K-K-I-N-V-L-K-V-V-R-T-I-T-G-L-G-L-K-E-A-K-E-L-V-D-S-V-P-K-T-L-K-E-G-L-S-A-S-E-A-E-Q-L-K-T-Q-L-T-E-A-G-A-Q-V-E-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-G-K-K-V-L-A-V-V-K-L-A-L-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-Y-G-V-N-L-V-M-F-T-K-E-Y-N-A-K-T-A-D-Q-I-G-L-I-I-P-A-Q-I-T-I-Y-E-D-K-S-Y-S-F-I-L-K-T-P-P-A-S-V-L-L-K-R-A-A-Q-I-E-K-G-S-N-N-G-T-I-V-A-S-I-T-Q-E-Q-L-Q-Q-I-A-L-T-K-L-P-D-L-N-T-K-D-V-K-K-A-M-S-I-I-S-G-T-A-A-N-M-G-I-Q-I-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-S-I-L-K-K-P-D-L-S-D-A-Q-L-R-A-K-L-A-K-G-M-G-H-N-M-Y-G-E-P-A-W-P-N-D-L-L-Y-T-F-P-V-V-I-L-G-T-I-T-C-C-I-G-L-A-L-M-E-P-S-A-I-G-E-A-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-Y-P-T-F-N-L-L-R-V-I-P-N-K-L-L-G-V-L-S-M-A-S-V-P-L-G-L-I-F-V-P-F-I-E-N-R-N-R-Y-Q-N-P-W-R-R-P-I-A-T-T-V-F-L-V-G-T-V-V-T-I-W-L-G-I-G-A-T-K-S-I-Q-D-A-I-S-L-G-L-F"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-K-T-Q-M-K-K-P-W-I-E-Y-E-L-M-W-L-I-R-P-D-L-N-Q-E-E-I-K-K-E-I-E-A-V-M-K-V-L-E-E-S-R-R-V-Q-L-N-G-K-T-T-R-K-L-A-Y-K-I-G-K-Y-E-E-G-H-Y-V-Q-M-E-F-D-G-Y-G-R-I-V-K-K-L-E-K-Y-L-Q-V-N-E-K-G-L-R-Y-M-I-L-R-K"} +{"text": "### FUNCTION May be involved in RNA polymerase activity ### SEQUENCE -M-K-L-L-N-Q-M-E-L-L-L-S-T-C-K-N-R-Y-V-L-T-R-E-V-A-E-Y-A-K-K-T-P-S-P-N-A-V-I-L-A-I-W-L-M-A-R-K-T-K"} +{"text": "### FUNCTION Manganese-binding polypeptide with L-arginine metabolizing enzyme activity Component of the core of photosystem II ### SEQUENCE -M-D-T-R-L-L-I-V-L-L-P-I-I-A-A-A-S-W-A-I-Y-N-I-G-K-I-L-L-L-Q-L-T-K-R-S"} +{"text": "### FUNCTION This protein binds to 23S rRNA ### SEQUENCE -M-S-P-T-A-Y-A-I-V-E-T-C-G-K-Q-Y-W-F-Q-P-G-R-Y-Y-D-I-N-F-I-N-A-E-P-G-D-K-I-I-F-H-R-V-L-W-L-Q-H-Q-Q-L-L-I-G-R-P-F-L-P-N-T-H-V-E-A-T-I-L-Q-H-L-K-S-K-K-V-L-V-Y-H-M-R-S-K-K-K-T-R-K-K-Y-G-A-R-Q-L-L-T-R-I-Y-I-H-P-F-H-G-S"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-H-L-V-F-L-L-M-K-F-Q-M-K-L-N-E-S-I-R-Y-A-S-I-L-V-I-D-E-S-G-N-P-L-G-V-F-T-S-E-Q-G-R-Q-L-A-A-K-K-G-L-D-L-L-L-I-N-P-N-A-D-P-P-V-C-K-I-V-N-Y-G-K-Y-K-F-E-L-E-K-K-A-K-A-K-R-K-N-Q-S-Q-L-K-E-I-Q-M-S-Y-N-M-E-E-H-D-Y-Q-V-R-L-S-Q-A-C-K-F-L-K-A-G-D-K-V-K-V-T-L-M-L-K-G-R-E-M-Q-H-L-E-L-A-Q-N-K-M-A-Q-F-Q-A-D-V-S-S-L-A-Q-L-A-K-P-P-S-Q-E-G-R-N-L-S-A-I-F-V-P-K-K-S"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-W-H-V-L-A-Q-L-T-V-L-A-F-V-I-A-V-G-P-I-T-L-I-W-L-S-N-K-K-D-A-L-L"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-L-K-N-K-T-K-K-T-E-V-Y-A-L-C-R-H-I-S-L-S-A-D-K-A-R-R-V-I-D-Q-I-R-G-R-S-Y-E-E-T-L-M-I-L-E-L-M-P-Y-R-A-C-Y-P-I-L-K-L-V-Y-S-A-A-S-N-A-A-Y-S-M-D-S-A-E-V-N-L-V-I-S-K-A-E-V-N-E-G-T-I-T-K-K-F-K-P-R-A-R-G-R-S-Y-V-I-K-R-T-T-C-H-I-T-I-V-V-K-D-I-S-L-D-K-Y-E-E-I-Y-S-F-K-N-P-I-W-K-N-T-I-D-V-Y-S-N-G-V-V-W-H-K-K"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-Q-D-L-K-T-Y-L-S-T-A-P-V-L-A-I-S-W-L-I-F-V-A-G-L-L-I-E-I-N-R-F-F-P-D-A-L-T-L-T-F-P-S-F"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-N-V-I-D-P-F-I-S-L-S-Y-W-P-S-A-G-G-F-G-S-N-T-N-I-L-E-T-N-I-I-N-P-S-V-V-L-S-V-L-I-Y-F-G-K-G-V-L-S-N-L-L-D-N-R-K-Q-K-I-L-N-T-I-R-N-S-E-E-L-C-K-G-A-I-D-Q-L-E-K-A-R-A-R-L-R-E-V-E-M-I-G-D-E-I-R-V-N-G-D-S-Q-V-E-R-E-K-E-D-L-I-N-A-A-S-E-N-L-E-Q-L-E-D-P-K-N-E-T-I-Y-S-E-Q-Q-R-A-I-D-Q-I-R-Q-Q-V-S-R-Q-A-L-R-R-T-I-G-T-L-N-S-R-F-K-I-E-L-H-L-R-T-I-N-Q-N-I-G-L-F-R-T-M-M-N-T-P-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-S-T-A-E-K-K-T-A-K-S-D-P-I-Y-H-N-R-L-V-N-M-V-V-N-R-I-L-K-N-G-K-K-S-L-A-Y-R-I-L-Y-R-A-I-K-N-I-Q-Q-K-T-E-K-N-P-L-S-V-L-R-Q-A-I-R-R-V-T-P-N-V-T-V-K-A-R-R-V-G-G-S-T-Y-R-V-P-T-E-I-R-S-T-Q-G-K-V-L-A-I-R-W-L-L-G-A-S-R-K-R-L-G-R-N-M-K-F-K-L-S-H-E-L-M-D-A-A-R-G-N-G-N-A-I-R-K-K-E-E-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-R-K-S-L-I-Q-R-E-K-K-R-Q-A-L-E-R-K-Y-H-L-I-R-Q-S-L-E-E-K-S-K-V-S-S-L-D-D-K-W-E-I-H-R-K-L-Q-S-S-P-R-N-S-A-P-T-R-L-H-R-R-C-S-S-T-G-R-P-R-A-N-Y-R-D-F-G-L-S-G-H-I-L-R-E-M-A-H-A-C-L-L-P-G-I-T-K-S-S-W"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-D-E-V-K-Y-P-V-L-T-E-K-S-I-R-L-L-E-R-N-Q-Y-T-F-N-V-D-L-Q-S-N-K-T-K-I-K-N-W-I-E-N-F-F-D-V-K-V-I-A-M-N-S-Y-R-L-P-E-K-G-G-K-R-G-S-M-I-V-H-P-I-R-C-K-R-M-I-I-T-L-R-T-G-D-S-I-P-L-F-S-E-Q"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-N-P-F-V-A-N-H-L-L-R-K-I-K-N-L-N-I-K-K-E-K-K-I-I-V-T-W-S-R-A-S-V-I-V-P-A-M-I-G-H-T-I-A-V-H-N-G-R-E-H-L-P-I-Y-V-T-D-R-M-V-D-H-K-L-G-E-F-A-P-T-L-L-F-Q-G-H-A-R-N-D-K-K-S-R-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-S-M-G-N-N-S-P-G-P-E-I-R-A-L-A-R-N-I-R-M-S-A-H-K-A-R-R-V-I-N-Q-I-R-G-R-S-Y-G-Q-A-L-M-I-L-E-L-M-P-Y-G-A-C-Y-P-I-S-Q-L-I-H-S-A-A-A-N-A-N-H-N-M-G-L-N-K-A-N-L-L-V-G-R-V-E-V-N-E-G-A-V-L-K-R-I-Q-P-R-A-Q-G-R-G-Y-P-I-Q-K-P-T-C-H-I-T-I-V-S-E-E-I-S-R-S-N-D-P-I-M-S-I-E-S-R-K-K-G-Y-V-W-R-R-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-N-D-T-I-A-N-L-I-T-S-I-R-N-A-D-M-V-E-K-G-T-V-R-V-T-A-T-N-I-T-K-N-I-G-R-I-L-L-R-E-G-F-I-E-D-V-R-E-H-Q-E-G-Q-K-S-F-L-I-S-T-S-K-Y-R-R-R-K-K-R-T-Y-M-T-T-S-K-R-T-S-K-P-G-L-R-I-Y-S-N-Y-R-E-I-P-K-V-L-G-G-M-G-I-V-I-L-S-T-S-Q-G-I-L-T-D-R-E-A-R-Q-K-K-I-G-G-E-I-L-C-Y-V-W"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-K-Q-N-L-I-H-A-E-G-L-V-T-E-S-L-P-N-G-M-F-R-V-L-T-D-N-G-C-Q-I-L-T-H-I-S-G-R-I-R-R-N-S-V-R-I-L-P-G-D-R-V-K-V-E-L-S-A-Y-D-L-T-K-G-R-I-I-Y-R-L-S-N-K-S"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-G-V-T-K-K-P-D-L-N-D-P-V-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-S-Y-I-F-P-V-V-I-L-G-T-I-A-C-T-I-G-L-A-V-L-E-P-S-M-I-G-E-P-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-L-F-P-V-F-Q-I-L-R-T-V-P-N-Q-I-L-R-T-V-P-N-K-L-L-G-V-L-L-M-A-S-V-P-A-G-S-L-T-V-P-F-L-E-N-V-N-Q-F-Q-N-P-F-R-R-P-V-A-T-T-V-S-L-I-G-T-A-V-A-L-W-L-G-I-G-A-A-L-P-I-D-E-S-L-T-L-G-L-F-Q-S-N-L-I-Q-L-S-N-I-K-I-F-Q-I-F-F-F-S-Y-I"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-G-G-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-T-L-N-L-R-V-L-S-P-N-R-V-I-W-D-S-E-V-Q-E-I-I-I-S-T-N-S-G-Q-M-G-V-L-P-N-H-V-S-L-V-T-A-V-D-I-G-V-M-K-I-R-L-N-G-K-W-S-T-M-A-L-M-G-G-F-A-K-I-D-K-D-R-I-T-I-L-V-N-N-A-E-R-D-V-D-I-D-L-Q-K-A-Q-E-T-F-R-R-A-K-A-C-L-V-Q-A-E-G-K-R-Q-V-I-E-A-D-V-A-L-K-R-A-R-T-L-L-E-A-I-N-A-S-P-S-D-S-N"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-I-I-P-N-L-P-F-N-L-P-F-N-L-P-F-N-L-P-F-N-L-P-S-I-L-P-S-I-L-V-P-L-V-G-L-L-L-P-A-I-T-M-V-L-S-H-L-Y-I-Q-N-D-E-I-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-D-T-T-G-R-I-P-L-W-L-I-G-T-V-T-G-I-I-V-I-G-L-L-G-I-F-F-Y-G-S-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-K-P-P-N-P-T-N-P-N-D-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-P-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-Q-D-L-K-T-Y-L-S-T-A-P-V-L-A-I-L-C-C-S-F-L-A-G-L-V-I-E-I-N-R-F-F-P-D-A-L-T-L-T-F-P-S-F-E-F-F-S-S-P"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-V-K-R-G-Y-I-A-R-K-R-R-K-K-I-L-A-F-V-S-G-S-R-G-A-H-S-K-L-F-R-T-A-N-Q-R-K-A-R-A-L-V-S-V-H-R-D-R-G-K-R-K-R-D-L-R-R-L-W-I-T-R-I-N-A-A-A-R-A-N-G-V-S-Y-N-R-F-I-Q-Y-L-Y-K-R-Q-L-L-P-N-R-K-T-L-A-Q-I-A-V-L-D-S-N-C-F-S-T-I-L-K-N-L-S-Y-D-E-I-N-R"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-N-L-G-F-I-A-V-L-M-F-L-A-I-P-T-A-F-L-L-I-P-Y-V-K-T-A-S-A-S-S-G-S-N"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-I-Q-Q-L-I-R-N-A-R-Q-P-I-E-N-R-K-K-S-P-A-L-R-G-C-P-Q-R-R-G-T-I-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-I-T-A-Y-I-P-G-I-D-H-N-L-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-A-A-E-V-K-D-R-Q-Q-G-R-S-K-Y-G-V-K-K-P-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-L-F-V-Y-A-V-V-V-F-F-I-S-L-F-I-F-G-F-L-S-N-D-P-G-R-N-P-G-R-K-E"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-P-V-I-F-N-I-C-L-D-D-A-F-I-H-S-N-N-P-F-F-G-K-L-P-E-A-Y-A-I-F-D-P-I-V-D-V-M-P-I-I-P-V-L-S-F-L-L-A-F-V-W-Q-A-A-V-S-F-R"} +{"text": "### FUNCTION May play a role in viral pathogenesis or transmission by insects vectors ### SEQUENCE -M-R-S-K-H-N-E-L-K-S-P-I-M-S-C-S-K-R-T-E-W-K-S-I-L-G-P-L-I-F-R-Q-Q-M-I-L-T-Q-N-L-N-Q-K-L-K-T-I-K-A-C-M-Y-Q-I-R-K-L-S-K-L-K-A-L-Y-R-G-L"} +{"text": "### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-A-R-V-V-A-L-V-L-L-G-L-L-S-L-T-G-L-E-A-V-Q-R-I-P-K-V-Q-V-Y-S-R-H-P-A-E-N-G-K-P-N-F-L-N-C-Y-V-S-G-F-H-P-P-E-I-E-I-D-L-L-K-N-G-E-K-M-K-V-D-R-S-D-L-S-F-S-K-D-W-S-F-Y-L-L-V-H-T-D-F-T-P-N-G-V-D-E-Y-S-C-R-V-Q-H-S-T-L-K-E-P-L-I-V-K-W-D-R-D-L"} +{"text": "### FUNCTION This is an intracellular thiol proteinase inhibitor Tightly binding reversible inhibitor of cathepsins L, H and B ### SEQUENCE -M-M-C-G-A-P-S-A-V-Q-P-A-T-A-E-T-Q-D-I-A-D-Q-V-R-S-Q-L-E-E-K-E-N-K-K-F-P-V-F-K-A-V-S-F-K-S-Q-V-V-A-G-T-N-Y-F-I-K-V-H-V-G-D-E-D-F-V-H-L-R-V-F-K-S-L-P-H-E-N-K-P-L-T-L-S-D-Y-Q-T-N-K-A-K-H-D-E-L-S-Y-F"} +{"text": "### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-A-R-V-V-A-L-V-L-L-G-L-L-S-L-T-G-L-E-A-V-Q-R-I-P-K-V-Q-V-Y-S-R-H-P-A-E-N-G-K-P-N-F-L-N-C-Y-V-S-G-F-H-P-P-E-I-E-I-D-L-L-K-N-G-E-K-M-K-V-D-R-S-D-L-S-F-S-K-D-W-S-F-Y-L-L-V-H-T-D-F-T-P-N-G-V-D-E-Y-S-C-R-V-Q-H-S-T-L-K-E-P-L-I-V-K-W-D-R-D-L"} +{"text": "### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-A-R-V-V-A-L-V-L-L-G-L-L-S-L-T-G-L-E-A-V-Q-R-I-P-K-V-Q-V-Y-S-R-H-P-A-E-N-G-K-P-N-F-L-N-C-Y-V-S-G-F-H-P-P-E-I-E-I-D-L-L-K-N-G-E-K-M-K-V-D-R-S-D-L-S-F-S-K-D-W-S-F-Y-L-L-V-H-T-D-F-T-P-N-G-V-D-E-Y-S-C-R-V-Q-H-S-T-L-K-E-P-L-I-V-K-W-D-R-D-L"} +{"text": "### FUNCTION May have a role in hematopoietic cell differentiation ### SEQUENCE -M-R-F-M-A-G-P-A-G-S-Q-N-P-G-P-M-C-F-H-S-S-L-Q-A-L-Y-T-V-L-L-I-V-L-V-M-M-S-L-V-F-G-K-F-V-P-V-N-W-E-R-P-Q-P-L-P-V-P-K-Y-L-R-C-Y-R-C-L-L-E-T-K-E-L-G-C-L-L-G-S-D-T-C-L-T-P-A-G-S-S-C-I-T-L-H-I-K-N-G-S-N-S-D-V-M-V-S-D-C-R-S-K-E-Q-M-S-D-C-S-H-T-Q-T-S-P-V-S-G-F-W-M-F-S-Q-C-C-F-L-G-F-L-Q"} +{"text": "### FUNCTION Inhibits gastrointestinal motility and gastric acid secretion Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains ### SEQUENCE -M-G-P-R-G-L-Q-L-L-A-V-L-L-A-L-G-L-C-A-P-A-G-A-Q-K-P-S-A-C-Q-C-S-R-I-E-A-S-H-R-K-N-C-G-F-P-G-I-S-A-S-E-C-F-N-T-G-C-C-F-D-S-R-V-P-N-V-P-W-C-F-H-P-L-P-K-Q-E-S-E-Q-C-V-M-E-V-A-A-R-K-N-C-G-Y-P-G-I-S-P-Q-E-C-A-S-R-N-C-C-F-S-D-T-I-R-N-V-P-W-C-F-F-P-I-L-N-Q-D-C-H-Y"} +{"text": "### FUNCTION Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents ### SEQUENCE -M-E-H-R-V-I-Y-V-L-V-L-V-C-A-L-T-L-S-S-L-A-Q-G-Q-Q-E-T-C-T-V-A-P-H-H-R-D-N-C-G-S-P-G-I-T-P-S-Q-C-K-D-K-G-C-C-F-D-N-T-V-R-G-V-P-W-C-Y-Y-P-V-A-V-D-N-P-P-E-E-E-C-P-F"} +{"text": "### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-E-S-R-W-G-I-V-V-I-G-L-L-C-C-V-S-W-V-E-A-I-T-S-S-P-K-I-Q-V-Y-T-R-S-P-A-E-N-G-K-H-N-H-L-N-C-Y-V-S-S-F-H-P-P-Q-I-T-I-R-L-L-R-N-G-E-E-M-P-N-V-E-R-S-D-L-S-F-S-N-D-W-T-F-H-R-L-V-H-T-G-F-V-P-N-D-K-D-V-F-E-C-E-V-T-H-N-S-V-T-K-S-V-K-W-D-R-D-N"} +{"text": "### FUNCTION Cytokine that plays important roles in allergic inflammation and immune response to parasite infection Synergizes with IL2 in regulating interferon-gamma synthesis Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells ### SEQUENCE -M-A-L-L-L-T-T-V-I-A-L-T-C-L-G-G-F-A-S-P-S-P-V-P-R-S-T-A-L-K-E-L-I-E-E-L-V-N-I-T-Q-N-Q-K-A-P-L-C-N-G-S-M-V-W-S-I-N-L-T-A-G-V-Y-C-A-A-L-E-S-L-I-N-V-S-G-C-S-A-I-E-K-T-Q-R-M-L-N-G-F-C-P-H-K-V-S-A-G-Q-F-S-S-L-R-V-R-D-T-K-I-E-V-A-Q-F-V-K-D-L-L-V-H-L-K-K-L-F-R-E-G-R-F-N"} +{"text": "### FUNCTION Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form Binds to G ### SEQUENCE -M-C-K-G-L-A-A-L-P-H-S-C-L-E-R-A-K-E-I-K-I-K-L-G-I-L-L-Q-K-P-E-S-A-V-D-L-V-I-P-Y-N-E-K-P-D-K-P-V-K-I-Q-K-P-S-L-D-E-A-L-Q-W-R-D-S-L-D-K-L-L-Q-N-N-Y-G-L-A-S-F-K-S-F-L-K-S-E-F-S-E-E-N-L-E-F-W-M-A-C-E-D-Y-K-K-I-K-S-P-V-K-M-A-E-K-A-K-K-I-Y-E-E-F-I-Q-S-E-A-P-K-E-V-N-I-D-H-F-T-K-E-I-T-M-K-N-L-V-E-P-S-P-S-S-F-D-V-A-Q-K-R-I-Y-A-L-M-E-K-D-S-L-P-R-F-V-R-S-E-F-Y-Q-E-F-I-K"} +{"text": "### FUNCTION Ubiquitin Exists either covalently attached to another protein, or free Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked Lys-6-linked may be involved in DNA repair ### SEQUENCE -M-Q-I-F-V-K-T-L-T-G-K-T-I-T-L-E-V-E-P-S-D-T-I-E-N-V-K-A-K-I-Q-D-K-E-G-I-P-P-D-Q-Q-R-L-I-F-A-G-K-Q-L-E-D-G-R-T-L-S-D-Y-N-I-Q-K-E-S-T-L-H-L-V-L-R-L-R-G-G"} +{"text": "### FUNCTION Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development Specifically protects free alpha-hemoglobin from precipitation ### SEQUENCE -M-A-L-I-Q-T-N-K-D-L-I-S-K-G-I-K-E-F-N-I-L-L-N-Q-Q-V-F-S-D-P-A-I-S-E-E-A-M-V-T-V-V-N-D-W-V-S-F-Y-I-N-Y-Y-K-K-Q-L-S-G-E-Q-D-E-Q-D-K-A-L-Q-E-F-R-Q-E-L-N-T-L-S-A-S-F-L-D-K-Y-R-N-F-L-K-S-S"} +{"text": "### FUNCTION Cytokine that plays important roles in allergic inflammation and immune response to parasite infection Synergizes with IL2 in regulating interferon-gamma synthesis Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells ### SEQUENCE -M-A-L-W-L-T-V-V-I-A-F-T-C-I-G-G-L-A-S-P-V-P-T-P-S-P-K-A-L-K-E-L-I-E-E-L-V-N-I-T-Q-N-Q-K-A-P-L-C-N-G-S-M-V-W-S-I-N-L-T-T-S-M-Y-C-A-A-R-E-S-L-I-N-I-T-N-C-S-V-I-Q-R-T-Q-R-M-L-N-A-L-C-P-H-K-L-S-A-K-V-S-S-E-H-V-R-D-T-K-I-E-V-T-Q-F-I-K-T-L-L-Q-H-S-R-N-V-F-H-Y-R-S-F-N-W-S-K-K-S"} +{"text": "### FUNCTION Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5 This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells ### SEQUENCE -M-Y-K-L-Q-L-L-S-C-I-A-L-T-L-A-L-V-A-N-S-A-P-T-L-S-S-T-K-D-T-K-K-Q-L-E-P-L-L-L-D-L-Q-F-L-L-K-E-V-N-N-Y-E-N-L-K-L-S-R-M-L-T-F-K-F-Y-M-P-K-K-A-T-E-L-K-H-L-Q-C-L-M-E-E-L-K-P-L-E-E-V-L-N-L-A-Q-S-K-N-S-H-L-T-N-I-K-D-S-M-N-N-I-N-L-T-V-S-E-L-K-G-S-E-T-G-F-T-C-E-Y-D-D-E-T-V-T-V-V-E-F-L-N-K-W-I-T-F-C-Q-S-I-Y-S-T-M-T"} +{"text": "### FUNCTION Cytokine that plays important roles in allergic inflammation and immune response to parasite infection Synergizes with IL2 in regulating interferon-gamma synthesis Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells ### SEQUENCE -M-A-L-W-L-T-V-V-I-A-F-T-C-I-G-G-L-A-S-P-V-P-T-P-S-P-K-A-L-K-E-L-I-E-E-L-V-N-I-T-Q-N-Q-K-A-P-L-C-N-G-S-M-V-W-S-I-N-L-T-T-S-M-Y-C-A-A-R-E-S-L-I-N-I-T-N-C-S-V-I-Q-R-T-Q-R-M-L-N-A-L-C-P-H-K-L-S-A-K-V-S-S-E-H-V-R-D-T-K-I-E-V-T-Q-F-I-K-T-L-L-Q-H-S-R-N-V-F-H-Y-R-S-F-N-W-S-K-K-S"} +{"text": "### FUNCTION May play a role in viral pathogenesis or transmission by insects vectors ### SEQUENCE -M-I-I-W-I-L-P-C-R-M-P-M-N-L-R-K-D-E-R-I-N-I-S-K-T-S-S-S-K-I-K-E-I-N-Q-L-R-H-I-I-R-K-K-N-R-Q-I-Q-I-L-I-I-M-L-N-I-L-R-C-C-H-R-M-K-E"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-H-S-R-S-R-S-R-S-R-Y-R-R-R-R-R-R-R-S-R-Y-R-S-R-R-R-R-Y-R-G-S-R-R-S-R-S-R-R-R-G-R-R-R-G-Y-S-R-R-R-Y-S-R-R-R-R-R-R-Y"} +{"text": "### FUNCTION Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens ### SEQUENCE -M-E-I-C-R-G-L-G-S-H-L-I-C-L-L-L-F-L-F-H-S-E-T-V-G-R-P-S-G-R-K-P-S-K-M-Q-A-F-R-I-W-D-V-N-Q-K-T-F-Y-L-R-N-N-Q-L-V-A-G-Y-L-Q-G-P-N-V-N-L-E-E-K-I-D-V-V-P-I-E-P-H-A-L-F-L-G-I-H-G-G-K-M-C-L-S-C-V-K-S-G-D-E-T-R-L-Q-L-E-A-V-N-I-T-D-L-S-K-N-R-K-Q-D-K-R-F-A-F-V-R-S-D-S-G-P-T-T-S-F-E-S-A-A-C-P-G-W-F-L-C-T-A-M-E-A-D-Q-P-V-S-L-T-N-M-P-D-K-G-V-M-V-T-K-F-Y-F-Q-E-D-E"} +{"text": "### FUNCTION Strongly inhibits juvenile hormone biosynthesis in vitro by the corpora allata from fifth-stadium larvae and adult females ### SEQUENCE -M-K-T-S-A-Y-N-V-Y-L-G-V-V-A-A-M-L-A-L-L-F-V-T-I-N-A-A-P-M-E-A-D-D-E-T-A-E-N-T-L-V-A-H-P-D-G-D-M-E-L-S-G-P-W-D-A-I-N-T-A-A-L-R-K-L-L-L-Q-L-D-A-E-D-R-M-G-G-V-T-R-S-W-P-Q-A-E-P-R-G-W-G-L-R-A-L-D-S-R-L-A-R-Q-W-R-A-D-K-R-Q-V-R-F-R-Q-C-Y-F-N-P-I-S-C-F-R-K"} +{"text": "### FUNCTION Electron carrier protein The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain ### SEQUENCE -M-S-D-I-I-A-R-G-N-V-E-N-G-D-K-L-F-K-A-R-C-A-Q-C-H-T-T-A-N-G-A-P-N-K-Q-G-P-N-L-Y-G-L-F-F-P-K-S-R-S-F-P-G-Y-A-Y-S-D-P-N-K-N-T-G-K-F-C-I-M-W-G-E-Q-T-L-F-D-Y-L-E-N-P-K-K-Y-I-P-K-T-K-M-A-F-A-G-F-K-S-E-Q-D-R-A-D-V-V-A-Y-L-E-Q-S-T-K"} +{"text": "### FUNCTION Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA ### SEQUENCE -M-S-S-S-L-V-F-Q-G-E-F-Q-H-I-I-R-I-Y-N-T-N-V-D-G-R-R-K-I-Q-Y-A-L-T-C-V-K-G-V-G-R-R-F-A-N-L-V-C-K-K-A-D-I-D-T-S-K-R-A-G-E-L-S-K-D-E-V-E-R-L-T-T-I-M-N-H-P-R-Q-Y-N-I-P-T-W-F-L-N-R-Q-K-D-I-K-D-G-K-Y-S-H-C-L-A-N-Q-I-D-V-K-F-R-E-D-L-E-R-L-K-K-I-R-A-H-R-G-V-R-H-H-F-G-L-R-V-R-G-Q-K-T-K-T-T-G-R-R-G-R-T-V-G-V-A-G-R-R"} +{"text": "### FUNCTION Acts as a non-catalytic accessory component of a dynein complex ### SEQUENCE -M-S-S-N-K-Y-I-I-N-V-K-N-A-D-M-P-D-F-M-Q-Q-D-A-T-E-C-T-I-K-A-F-E-E-T-N-I-E-R-D-I-A-M-I-I-K-K-E-F-D-K-K-Y-S-P-T-W-H-C-I-V-G-K-S-F-G-S-F-V-T-H-E-T-K-N-F-I-Y-F-N-I-N-K-H-S-V-L-L-F-K-A-G"} +{"text": "### FUNCTION May have a role in the cell cycle ### SEQUENCE -M-S-H-T-I-V-L-L-Q-T-T-M-G-K-S-S-R-T-F-M-D-Y-E-S-V-N-Q-A-I-E-G-I-C-N-M-Y-E-Q-R-L-K-Q-E-R-P-N-Q-K-N-I-T-Y-D-I-S-Q-L-F-K-F-I-D-S-L-A-D-L-S-C-L-V-Y-T-S-H-I-N-A-Y-T-P-Y-N-K-E-W-I-K-T-K-I-I-N-H-L-Q-K-L-A-Q"} +{"text": "### FUNCTION Involved in the biogenesis of the 60S ribosomal subunit Ensures the docking of nog1 to pre-60S particles Activates and recruits ATPase AFG2 to cytoplasmic pre-60S ribosomal particles ### SEQUENCE -M-R-I-E-K-C-Y-F-C-S-G-P-V-Y-P-G-H-G-V-M-F-V-R-N-D-C-K-Q-F-R-F-C-R-S-K-C-H-K-N-F-K-L-K-R-N-P-R-K-T-R-W-T-K-A-F-R-K-L-N-G-K-E-M-T-V-D-K-T-L-E-F-E-K-K-R-N-R-P-V-K-Y-D-R-E-L-I-N-N-T-I-I-A-M-A-R-V-Q-K-I-K-E-R-R-E-K-T-F-Y-K-N-R-M-E-G-V-K-G-M-Q-K-K-Q-K-L-K-E-I-N-Q-N-L-S-L-I-R-G-P-S-A-L-N-K-L-Q-E-R-I-K-N-N-A-E-K-I-E-Q-L-T-T-T-K-M-Q-S"} +{"text": "### FUNCTION This protein markedly relaxes the rat carbachol-precontracted anococcygeus muscle This relaxation is inhibited by the inhibitor of nitric oxide ### SEQUENCE -M-N-Y-L-I-V-I-S-F-A-L-L-L-M-T-S-V-E-S-G-R-D-A-Y-I-A-D-S-E-N-C-T-Y-F-C-G-S-N-P-Y-C-N-D-L-C-T-E-N-G-A-K-S-G-Y-C-Q-W-A-G-R-Y-G-N-A-C-W-C-I-D-L-P-D-K-V-P-I-R-I-P-G-P-C-R-G-R"} +{"text": "### FUNCTION Lethal neurotoxin that blocks neuromuscular transmission ### SEQUENCE -M-K-V-T-L-I-A-I-L-T-C-A-A-V-L-V-L-H-T-T-A-A-E-E-L-E-E-S-Q-L-M-E-V-G-M-P-D-T-E-L-A-A-V-D-E-E-R-L-F-E-C-S-I-S-C-E-I-E-K-K-G-E-S-C-K-P-K-K-C-K-G-G-W-K-C-K-F-N-M-C-V-K-V"} +{"text": "### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase to ubiquinol Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants May act together with SDHAF1 ### SEQUENCE -M-N-N-L-S-K-N-D-F-L-K-L-Y-R-N-I-L-R-C-H-K-I-L-Q-E-P-M-R-S-M-G-D-Q-Y-V-K-T-E-W-K-L-H-K-K-A-T-P-K-Q-A-I-Q-F-Y-E-Q-W-N-I-Y-C-N-I-L-L-T-Q-R-D-S-I-L-K-E-N-S-N-N-N-D-N-Y-N-N-N-N-N-D-N-N-N-D-N-N-N-F-I-N-I-G-Q-D-L-N-E-K-Q-M-K-S-L-N-K-K-Q-I-E-Q-L-D-K-L-K-S-E-T-S-T-V-Y-T-P-S-D-K"} +{"text": "### FUNCTION Controls actin polymerization and depolymerization ### SEQUENCE -M-E-S-R-I-I-E-I-D-P-N-C-V-N-E-F-E-K-L-K-K-K-Y-K-I-E-S-I-F-L-K-L-N-D-N-F-N-L-L-Y-V-E-K-T-L-S-K-I-S-Q-D-D-F-L-E-S-I-P-V-D-Q-P-R-L-I-I-Y-K-K-Y-S-N-N-K-I-I-F-I-R-W-I-P-E-I-V-Q-D-T-I-E-Y-S-Y-S-N-A-S-T-A-I-L-E-L-L-I-G-I-N-E-Y-M-E-V-K-D-L-I-Q-L-S-N-L"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-V-G-Y-R-Q-K-W-V-Q-D-L-P-P-A-G-G-F-P-K-L-K-Y-A-R-T-S-T-S-P-I-P-G-A-Y-I-F-A-G-V-F-S-I-M-A-V-G-T-Y-I-F-F-S-D-K-V-E-R-N-A-R-E-E-E-E-K-R-R-L-S-M-I-L-P-I-L-Q-A-E-N-D-I-N-F-L-A-S-P-H-Q-N-V-Y-F-T-R-W-M-P-P-Q-T-G-K-R-A-A-A-L-L-R-D-L"} +{"text": "### FUNCTION Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids May activate the TOR signaling cascade in response to amino acids ### SEQUENCE -M-E-K-V-D-E-F-L-E-Y-I-K-V-S-I-L-D-K-S-I-V-D-T-S-L-I-L-S-D-R-D-G-F-V-L-G-K-I-I-D-K-S-S-S-A-D-N-V-I-D-N-S-L-I-S-T-F-S-S-A-T-D-Q-A-S-K-L-H-A-G-N-N-K-S-I-V-S-F-F-E-D-R-I-I-V-H-I-N-V-S-N-V-I-L-S-I-I-T-D-T-E-S-N-V-G-L-I-L-G-S-Q-D-D-L-I-R-S-L-T-S-L-S-N-S-I-Q-S-D-I-Q-D-M"} +{"text": "### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs Pol II is the central component of the basal RNA polymerase II transcription machinery It is composed of mobile elements that move relative to each other RPB11 is part of the core element with the central large cleft ### SEQUENCE -M-N-A-P-D-R-F-E-L-F-V-L-P-D-G-A-K-K-V-T-M-V-R-D-T-K-I-P-N-A-S-M-F-T-I-L-K-E-D-H-T-I-G-N-L-I-R-M-Q-L-I-A-D-Q-D-I-I-F-A-G-Y-R-M-P-H-P-L-E-H-N-V-N-I-R-I-Q-T-N-N-N-T-N-P-L-E-C-V-Q-K-S-M-E-C-L-S-R-E-F-T-S-L-E-N-S-F-I-E-Q-V-Q-K-K-R-N-V-A-D-Q-Y-I"} +{"text": "### FUNCTION May play a role in vesicular transport from endoplasmic reticulum to Golgi ### SEQUENCE -M-S-K-K-Y-D-K-L-G-N-D-V-F-N-K-V-E-K-I-N-S-E-L-F-T-L-T-Y-G-A-L-V-T-Q-L-I-K-D-Y-E-D-I-E-Q-V-N-I-K-L-E-Q-M-G-Y-N-I-G-I-R-L-I-E-E-F-L-A-K-S-G-I-G-R-C-S-D-F-I-E-T-A-E-V-I-A-K-V-G-F-K-M-F-L-G-V-N-A-H-V-G-D-W-D-A-N-R-K-E-F-H-L-T-I-E-D-N-P-L-I-D-F-V-E-L-P-D-Q-Y-K-H-K-L-Y-Y-S-N-I-L-C-G-V-M-R-G-A-L-E-M-V-Q-M-K-V-K-C-T-F-V-K-C-T-L-S-D-D-S-T-S-E-I-K-V-V-L-E-E-V-L-S-D-M-I-P-V-G-Y-D"} +{"text": "### FUNCTION May play a role in cell cycle regulation May play a role as translation enhancer by binding to the cap complex of the 5'-terminus of mRNAs ### SEQUENCE -M-F-K-K-L-S-L-K-G-S-S-N-T-N-N-Q-I-K-S-S-L-Q-R-N-I-K-N-S-I-L-A-Q-Y-P-K-L-K-D-I-E-E-D-V-F-P-K-K-V-P-I-V-Q-V-K-C-Q-N-H-I-N-L-V-L-I-N-N-E-V-L-F-F-N-E-R-E-G-P-Y-Y-P-T-L-R-F-L-H-K-Y-P-N-I-L-P-H-V-Q-V-D-K-G-A-I-K-F-V-L-Q-G-A-N-I-M-C-R-G-L-T-S-P-G-A-K-M-E-V-D-L-P-V-D-A-I-V-A-V-M-A-E-G-K-D-H-A-S-A-I-G-V-M-K-M-S-T-N-D-I-R-T-I-N-N-D-I-G-I-N-N-I-H-Y-L-G-D-S-L-Y-M-S-P-N-L-E"} +{"text": "### FUNCTION Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis They bind voltage-independently at site-4 of sodium channels ### SEQUENCE -M-K-L-F-L-L-L-V-I-S-A-S-M-L-I-D-G-L-V-N-A-D-G-Y-I-R-G-S-N-G-C-K-V-S-C-L-W-G-N-E-G-C-N-K-E-C-K-A-F-G-A-Y-Y-G-Y-C-W-T-W-G-L-A-C-W-C-E-G-L-P-D-D-K-T-W-K-S-E-S-N-T-C-G-G-K-K"} +{"text": "### FUNCTION Cardioactive peptide Corazonin is probably involved in the physiological regulation of the heart beat ### SEQUENCE -M-V-T-N-I-T-L-I-L-T-L-M-T-L-A-S-V-T-A-Q-T-F-Q-Y-S-R-G-W-T-N-G-K-R-D-G-H-K-R-D-E-L-R-D-E-V-L-E-R-I-L-T-P-C-Q-L-D-K-L-K-Y-V-L-E-G-K-P-L-N-D-R-L-F-V-P-C-D-Y-I-E-E-E-V-N-Q-P-K-R-Y-K-G-E-R-N-H-E-L-F-D-V-F-Q"} +{"text": "### FUNCTION Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria ### SEQUENCE -M-N-F-N-K-L-F-L-I-V-I-L-A-A-L-L-L-L-G-Q-T-E-A-G-R-S-K-K-L-G-K-K-I-E-K-A-G-K-R-V-F-N-A-A-Q-K-G-L-P-V-A-A-G-V-Q-A-L-G-R"} +{"text": "### FUNCTION Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria ### SEQUENCE -M-N-F-N-K-L-F-L-I-V-I-L-A-A-L-L-L-L-G-Q-T-E-A-G-R-L-K-K-L-G-K-K-I-E-K-A-G-K-R-V-F-N-A-V-Q-K-G-L-P-V-A-A-G-V-Q-A-L-G-R"} +{"text": "### FUNCTION Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria ### SEQUENCE -M-N-F-N-K-L-F-V-I-V-L-L-A-A-L-A-F-F-G-Q-A-E-A-G-G-L-K-K-F-G-K-K-L-E-G-V-G-K-R-V-F-K-A-S-E-K-A-L-P-V-V-T-G-F-K-A-L-G-K"} +{"text": "### FUNCTION Significantly inhibits the growth of Gram-negative and Gram-positive bacteria and fungi in vitro ### SEQUENCE -M-E-K-K-T-A-Y-C-L-L-F-L-V-L-L-V-P-Y-T-A-L-G-A-V-L-K-R-A-P-A-K-K-E-K-R-A-V-P-L-A-V-P-L-V-Y-W-G-A-S-V-S-P-A-V-W-N-W-L-L-V-T-F-G-A-A-A-V-A-A-A-A-V-T-V-S-D-N-D-S-H-S-C-A-N-N-R-G-W-C-R-S-R-C-F-S-H-E-Y-I-D-S-W-H-S-D-V-C-G-S-Y-D-C-C-R-P-R-Y"} +{"text": "### FUNCTION Neurotoxin that blocks voltage-independent calcium-activated potassium channels ### SEQUENCE -M-I-S-M-L-R-C-I-S-L-F-L-S-V-I-L-I-T-G-Y-F-V-T-P-V-M-S-C-N-C-K-A-P-E-T-A-L-C-A-R-R-C-Q-Q-H-G"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-Q-C-A-K-Y-G-Y-Y-Y-Q-C-D-E-C-C-K-K-A-G-D-R-A-G-T-C-E-Y-F-K-C-K-C-N-P"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-K-C-A-K-Y-G-Y-Y-Y-Q-C-D-E-C-C-K-K-A-G-D-R-A-G-T-C-E-Y-F-K-C-K-C-N-P"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-K-C-G-K-Y-G-Y-Y-G-Q-C-D-E-C-C-K-K-A-G-D-R-A-G-I-C-E-Y-Y-K-C-K-C-N-P"} +{"text": "### FUNCTION Blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-A-K-Y-G-Y-Y-Q-E-C-Q-D-C-C-K-K-A-G-H-S-G-G-T-C-M-F-F-K-C-K-C-A"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-A-K-Y-G-Y-Y-G-Q-C-E-V-C-C-K-K-A-G-H-N-G-G-T-C-M-F-F-K-C-M-C-V-N-S-K-M-N"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-G-K-Y-G-Y-Y-G-Q-C-D-E-C-C-K-K-A-G-D-R-A-G-T-C-V-Y-Y-K-C-K-C-N-P"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-G-K-Y-G-Y-Y-G-Q-C-D-D-C-C-K-K-A-G-D-R-A-G-T-C-V-Y-Y-K-C-K-C-N-P"} +{"text": "### FUNCTION Blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-A-K-Y-G-Y-Y-G-Q-C-E-V-C-C-K-K-A-G-H-R-G-G-T-C-D-F-F-K-C-K-C-K-V"} +{"text": "### FUNCTION Blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-A-K-Y-G-Y-Y-Q-E-C-Q-D-C-C-K-K-A-G-H-N-G-G-T-C-M-F-F-K-C-K-C-A"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-K-C-A-K-Y-G-Y-Y-G-Q-C-D-E-C-C-K-K-A-G-D-R-A-G-N-C-V-Y-L-K-C-K-C-N-Q"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-K-C-S-K-Y-G-Y-Y-G-Q-C-D-K-C-C-K-K-A-G-D-R-A-G-N-C-V-Y-F-K-C-K-C-N-Q"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-K-C-S-K-Y-G-Y-Y-G-Q-C-D-E-C-C-K-K-A-G-D-R-A-G-N-C-V-Y-F-K-C-K-C-N-P"} +{"text": "### FUNCTION Blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-S-K-Y-G-Y-Y-Q-E-C-Q-D-C-C-K-K-A-G-H-N-G-G-T-C-M-F-F-K-C-K-C-A"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-Q-K-Y-G-P-Y-G-Q-C-T-D-C-C-K-K-A-G-H-T-G-G-T-C-I-Y-F-K-C-K-C-G-A-E-S-G-R"} +{"text": "### FUNCTION Blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-Q-K-Y-G-N-Y-A-Q-C-T-A-C-C-K-K-A-G-H-N-K-G-T-C-D-F-F-K-C-K-C-T"} +{"text": "### FUNCTION Blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-A-K-Y-G-H-Y-Q-E-C-T-D-C-C-K-K-Y-G-H-N-G-G-T-C-M-F-F-K-C-K-C-A"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-K-C-G-K-Y-G-Y-Y-H-Q-C-D-E-C-C-K-K-A-G-D-R-A-G-N-C-V-Y-Y-K-C-K-C-N-P"} +{"text": "### FUNCTION Blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-A-K-Y-G-Y-Y-Q-Q-C-E-I-C-C-K-K-A-G-H-R-G-G-T-C-E-F-F-K-C-K-C-K-V"} +{"text": "### FUNCTION Blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-R-C-A-K-Y-G-Y-Y-Q-E-C-T-D-C-C-K-K-Y-G-H-N-G-G-T-C-M-F-F-K-C-K-C-A"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-K-C-G-K-Y-G-Y-Y-Q-E-C-Q-D-C-C-K-N-A-G-H-N-G-G-T-C-V-Y-Y-K-C-K-C-N-P"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-Q-C-G-K-Y-G-Y-Y-G-Q-C-D-E-C-C-K-K-A-G-E-R-V-G-T-C-V-Y-Y-K-C-K-C-N-P"} +{"text": "### FUNCTION Reversibly blocks Kv11/ERG potassium channels ### SEQUENCE -D-R-D-S-C-V-D-K-S-K-C-G-K-Y-G-Y-Y-G-Q-C-D-E-C-C-K-K-A-G-D-R-A-G-T-C-V-Y-Y-K-C-K-C-N-P"} +{"text": "### FUNCTION Serine protease inhibitor ### SEQUENCE -M-K-F-V-F-A-S-F-A-L-F-V-I-F-L-C-F-S-Q-S-L-S-Q-S-Y-F-R-C-R-D-N-E-V-F-D-N-C-I-S-N-C-G-P-P-R-C-S-N-I-L-N-T-Y-P-C-T-N-L-G-P-L-C-T-P-G-C-K-C-K-D-G-R-V-Y-D-N-Q-G-R-C-V-L-Q-T-E-C-F-Q-K"} +{"text": "### FUNCTION Blocker of A-type voltage-gated potassium channels of cerebellar granular cells May also inhibit Kv4/KCND when coexpressed with DPP6 or DPP10 The occlusion of the outer entry of the K ### SEQUENCE -M-K-F-S-S-I-I-L-L-T-L-L-I-C-S-M-S-I-F-G-N-C-Q-V-E-T-N-K-K-C-Q-G-G-S-C-A-S-V-C-R-R-V-I-G-V-A-A-G-K-C-I-N-G-R-C-V-C-Y-P"} +{"text": "### FUNCTION Unknown Candidate gene encoding tumor antigens ### SEQUENCE -M-A-A-G-A-V-F-L-A-L-S-A-Q-L-L-Q-A-R-L-M-K-E-E-S-P-V-V-S-W-R-L-E-P-E-D-G-T-A-L-C-F-I-F"} +{"text": "### FUNCTION Unknown Candidate gene encoding tumor antigens ### SEQUENCE -M-A-A-G-A-V-F-L-A-L-S-A-Q-L-L-Q-A-R-L-M-K-E-E-S-P-V-V-S-W-W-L-E-P-E-D-G-T-A-L"} +{"text": "### FUNCTION Unknown Candidate gene encoding tumor antigens ### SEQUENCE -M-A-A-G-V-V-F-L-A-L-S-A-Q-L-L-Q-A-R-L-M-K-E-E-S-P-V-V-S-W-R-L-E-P-E-D-G-T-A-L-D-V-H-F-V-S-T-L-E-P-L-S-N-A-V-K-R-N-V-P-R-C-I-I-I-L-V-L-Q-E-P-T-P-F-R-I-S-V-T-S-S-C-F-V-Q-N-T-L-T-K-L-L-K-D-R-R-K-M-Q-T-V-Q-C-A-T-A-Q-E-T-S"} +{"text": "### FUNCTION Unknown Candidate gene encoding tumor antigens ### SEQUENCE -M-A-A-G-V-V-F-L-A-L-S-A-Q-L-L-Q-A-R-L-M-K-E-E-S-P-V-V-S-W-R-L-E-P-E-D-G-T-A-L-D-V-H-F-V-S-T-L-E-P-L-S-N-A-V-K-R-N-V-P-R-C-I-I-I-L-V-L-Q-E-P-T-A-F-R-I-S-V-T-S-S-C-F-V-Q-N-T-L-T-K-L-L-K-D-R-R-K-M-Q-T-V-Q-C-A-T-A-R-E-T-S"} +{"text": "### FUNCTION May transport viral genome to neighboring plant cells directly through plasmosdesmata, without any budding The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier ### SEQUENCE -M-D-S-G-D-G-Y-N-T-Y-S-Y-E-E-G-A-G-D-A-K-K-E-V-L-Y-K-I-G-I-I-M-L-C-I-V-G-I-V-V-L-W-V-L-I-I-L-C-C-A-V-P-R-Y-A-K-S-T-M-D-A-W-L-S-S-S-S-I-M-K-R-K-M-A-S-R-I-T-G-T-P-F-E-E-T-G-P-H-R-E-R-R-W-A-E-R-R-T-E-A-T-N-Q-N-N-N-D-N-V-N-R-F-S"} +{"text": "### FUNCTION Interacts with and disrupts the function of host retinoblastoma-related proteins RBR, which are key regulators of the cell cycle Induces transcriptional activation of E2F-regulated S-phase and G2/M-phase-specific genes Inactivation of the ability of RBR to arrest the cell cycle leads to the stimulation of viral DNA replication ### SEQUENCE -M-A-L-R-Y-F-S-H-L-P-E-E-L-K-E-K-I-M-N-E-H-L-K-E-I-K-K-K-E-F-L-E-N-V-I-K-A-A-C-A-V-F-E-G-L-T-K-K-E-S-V-E-E-D-D-I-L-R-F-S-G-F-L-E-G-L-S-A-Y-Y-A-E-A-T-K-K-K-C-L-V-R-W-K-K-S-V-A-I-N-L-K-W-R-V-M-E-E-M-H-Y-K-L-Y-G-F-A-D-M-E-D-L-Y-C-S-E-L-G-F-P-N-Y-G-E-D-D-V-A-Y-H-D-G-A-I-V-N-C-K-Q-L-E-V-V-F-D-D-L-G-I-E-F-M-S-I-V-I-D-R-G-S-I-K-I-E-L"} +{"text": "### FUNCTION Putative nuclear shuttle protein ### SEQUENCE -M-A-D-W-F-H-S-A-L-K-T-C-T-H-V-C-D-F-S-D-I-K-A-S-S-Q-Q-D-F-F-C-C-D-S-M-R-G-K-L-S-E-P-R-K-V-L-L-V-S-C-F-V-S-F-T-G-S-F-Y-G-S-N-R-N-V-R-G-Q-V-Q-L-G-M-Q-Q-D-D-G-V-V-R-P-I-G-Y-I-P-I-G-G-Y-L-Y-H-D-D-Y-G-Y-Y-Q-G-E-K-T-F-N-L-D-I-E-S-D-Y-L-K-P-D-E-D-F-W-K-R-F-T-I-N-I-V-N-D-K-G-L-D-D-R-C-D-V-K-C-Y-V-V-H-T-M-R-I-K-V"} +{"text": "### FUNCTION Plays a role in the regulation of membrane potential Could mediate a proton leak ### SEQUENCE -M-A-F-T-A-S-D-I-C-K-I-I-V-A-V-I-L-P-P-L-G-V-F-F-E-R-G-C-G-A-D-L-F-I-N-I-L-L-T-I-L-G-Y-L-P-G-I-V-H-A-L-Y-I-I-L-K-Y"} +{"text": "### FUNCTION Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP pathway ### SEQUENCE -M-S-A-W-D-T-D-A-V-K-I-G-K-N-V-S-R-G-G-A-G-P-R-E-T-V-V-R-G-K-S-A-L-N-A-A-Q-R-S-G-N-I-I-A-T-E-K-K-Y-A-A-G-N-T-A-S-K-P-G-V-E-G-Q-R-L-T-M-V-D-R-S-D-D-I-V-K-P-K-T-V-S-K-E-V-G-A-A-I-Q-K-A-R-S-A-I-M-I-G-D-K-A-M-T-Q-K-E-L-A-T-R-C-N-S-T-Q-A-I-I-A-Q-Y-E-R-G-E-G-V-P-D-Q-K-L-L-G-N-L-E-R-V-L-N-V-K-L-R-G-S-D-I-G-K-P-K-F-E-K-K-E-K-K"} +{"text": "### FUNCTION Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide ### SEQUENCE -M-P-E-Q-Q-R-L-A-S-L-D-S-S-T-A-S-R-L-P-A-Y-S-Q-T-L-F-E-A-K-T-E-K-G-L-T-F-E-A-I-A-Q-H-L-G-R-S-E-V-A-V-A-G-L-F-Y-G-Q-V-Q-A-S-A-E-D-V-D-K-L-S-E-L-L-S-V-P-K-E-A-I-A-K-Q-M-M-G-F-P-D-R-G-R-A-G-P-M-P-P-V-E-P-L-I-Y-R-L-Y-E-I-V-Q-N-Y-G-Y-A-F-K-A-V-M-N-E-K-F-G-D-G-I-M-S-A-I-C-F-N-T-T-V-D-K-E-V-D-E-T-G-A-S-W-V-V-I-T-L-K-G-K-W-L-P-F-A-R-F"} +{"text": "### FUNCTION General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery Binds single-stranded DNA ### SEQUENCE -M-P-P-K-R-R-Q-A-E-D-T-S-D-A-E-P-Q-Y-T-K-K-S-K-G-N-T-G-K-A-Q-P-Q-E-L-T-K-G-S-D-Q-D-G-N-T-F-W-E-L-G-N-N-R-R-I-S-S-S-V-F-R-N-T-T-L-V-N-I-R-E-Y-Y-D-A-G-G-K-L-M-P-G-K-K-G-I-S-L-S-L-A-Q-Y-Q-N-L-L-K-V-I-P-Q-L-N-A-D-L-R-A-Q-G-H-A-I-E-D-P-G-F-A-Q-V-A-E-Q-T-D-A-P-I-E-T-P-K-V-K-A-L-E-S-N-K-E-S-I-K-K-E-K-K-K-P-R-K-S-N-I-D-V-T-S-D-E-E-E-A-A-E-D-E-D-D-D-E"} +{"text": "### FUNCTION Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH At alkaline ambient pH, activates transcription of alkaline-expressed genes ### SEQUENCE -E-R-H-V-G-R-K-S-T-N-N-L-N-L-T-C-Q-W-G-T-C-N-T-T-T-V-K-R-D-H-I-T-S-H-I-R-V-H-V-P-L-K-P-H-K-C-D"} +{"text": "### FUNCTION Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases ### SEQUENCE -M-T-D-T-D-T-T-T-T-I-Y-T-H-E-E-V-A-Q-H-T-T-H-D-D-L-W-V-I-L-N-G-K-V-Y-N-I-S-N-Y-I-D-E-H-P-G-G-E-E-V-I-L-D-C-A-G-T-D-A-T-E-A-F-D-D-I-G-H-S-D-E-A-H-E-I-L-E-K-L-Y-I-G-N-L-K-G-A-K-I-V-E-A-K-H-A-Q-S-F-S-T-E-E-D-S-G-I-N-F-P-L-I-A-V-G-V-F-L-A-A-F-G-V-Y-Y-Y-K-T-N-F-A"} +{"text": "### FUNCTION Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion Transcriptional activator that induces the transcription of alpha-specific genes ### SEQUENCE -M-S-V-K-T-K-K-F-V-N-K-K-Y-T-T-A-K-F-K-V-T-P-T-G-K-C-R-N-K-N-N-E-S-I-K-K-L-I-F-N-N-G-T-K-I-N-T-G-L-N-L-L-L-T-Q-P-N-Q-V-N-I-P-P-P-P-K-I-L-L-D-R-I-R-E-E-R-K-R-M-V-S-S-A-N-S-D-I-T-V-I-D-I-E-L-C-W-E-I-D-K-F-L-A-H-H-F-Q-N-T-D-S-S-K-N-D-N-Y-T-K-S-N-I-K-K-P-I-N-A-F-I-A-F-R-A-Y-Y-S-Q-L-G-A-G-I-K-Q-N-I-L-S-S-I-L-S-E-A-W-N-S-P-E-T-D-Q-N-I-W-D-I-F-A-Q-Q-F-N-F-A-S-A-R-C-G-F-V-N-Y-I-M-A-Q-A-S-S-A-P"} +{"text": "### FUNCTION Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion Transcriptional corepressor that acts in conjunction with A1 to repress transcription of haploid-specific genes and of MATALPHA1 ### SEQUENCE -M-E-S-K-K-I-A-I-T-E-L-L-N-P-S-N-Q-E-N-L-K-E-K-L-Q-E-I-N-K-Q-L-I-S-L-C-S-S-L-P-K-R-N-W-V-P-A-P-S-S-D-I-L-R-S-L-S-R-T-K-L-D-S-Q-E-I-R-L-I-K-T-T-Y-R-L-S-T-L-L-S-K-L-Q-E-K-D-I-V-F-N-V-V-T-K-D-H-L-L-K-N-G-T-P-Y-N-P-Y-P-Q-P-Y-R-G-H-R-F-T-K-E-N-V-H-T-L-E-A-W-Y-S-N-H-I-D-N-P-Y-L-D-P-K-S-L-Q-S-L-A-Q-K-T-N-L-S-K-I-Q-I-K-N-W-V-S-N-R-R-R-K-Q-K-H-P-P-F-L-L-I"} +{"text": "### FUNCTION Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase Confers calcium sensitivity ### SEQUENCE -M-G-A-A-P-S-R-I-V-D-N-L-L-D-D-T-N-F-D-R-A-E-I-E-R-L-K-K-R-F-M-K-L-D-K-D-S-S-G-S-I-D-K-T-E-F-M-S-I-P-G-V-S-A-N-P-L-A-K-R-I-I-E-V-F-D-E-D-N-S-G-D-V-D-F-Q-E-F-I-T-S-L-S-I-F-S-G-R-G-E-T-D-A-K-L-R-F-A-F-R-I-Y-D-I-D-K-D-G-Y-I-S-N-G-E-L-F-I-V-L-K-I-M-V-G-T-N-L-E-D-E-Q-L-Q-Q-I-V-D-R-T-I-M-E-N-D-V-D-G-D-G-K-L-S-F-E-E-F-K-K-A-A-E-T-T-E-V-I-Q-S-L-T-L-Q-H-N-I"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-M-A-V-L-V-R-T-D-L-D-M-G-K-G-K-I-A-A-Q-V-A-H-A-A-V-S-L-V-L-E-I-V-Q-K-R-S-K-A-E-W-K-E-W-L-E-M-W-I-N-Q-G-Q-P-K-I-V-L-K-V-K-N-L-D-E-L-L-E-K-Y-N-K-A-L-Q-S-G-L-P-A-T-I-I-Q-D-A-G-K-T-Q-I-E-P-G-T-I-T-C-A-G-I-G-P-G-P-E-E-M-I-D-N-I-T-G-D-L-K-L-L"} +{"text": "### FUNCTION Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs ### SEQUENCE -M-E-V-W-G-G-K-S-Y-F-K-V-E-F-V-D-N-P-K-K-I-V-K-S-W-R-E-K-G-G-L-V-V-H-L-T-M-Y-G-K-M-I-D-D-M-I-D-E-I-T-K-A-S-K-N-F-T-L-P-L-L-V-V-I-G-S-E-K-V-E-G-W-Y-Y-Y-N-S-D-Y-N-I-G-I-G-N-Q-P-H-S-E-V-S-A-L-A-I-F-L-D-R-I-Y-K-G-E-E-L-Y-I-H-F-S-D-A-K-F-Y-I-I-P-Q-L-K-G-K-R-V-V-K-T-D-K"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-S-C-K-R-F-P-R-S-A-R-I-C-L-P-S-E-Y-Y-V-A-F-E-Q-G-R-R-Y-S-S-V-L-L-R-L-H-H-L-P-T-S-G-P-V-R-L-G-L-V-V-S-R-R-V-D-I-R-A-V-N-R-N-R-I-K-R-A-L-R-E-V-M-R-Q-I-A-Y-K-L-V-P-G-D-Y-V-V-V-V-R-Q-T-A-K-D-V-S-N-A-E-L-S-V-A-L-L-S-L-L-R-R-I-G-A-L-P-L-A-S-I-D-N-A-M-L-P-F-F-E-R-N-C-S-R-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-L-G-L-R-L-I-V-G-L-G-N-P-G-S-E-Y-I-K-T-R-H-N-A-G-F-R-F-V-D-G-L-V-Q-R-E-G-Q-C-W-A-L-E-S-K-L-F-A-Y-V-A-R-V-F-I-A-G-Q-W-V-W-L-L-R-P-V-T-F-M-N-L-S-G-K-S-I-C-A-G-L-N-F-W-K-I-K-P-E-Q-M-L-V-A-H-D-E-L-D-F-P-P-G-A-V-R-L-K-F-D-G-G-H-G-G-Q-N-G-L-R-D-I-T-K-L-L-G-H-G-R-F-H-R-L-R-V-G-I-G-H-P-G-H-K-D-R-V-V-S-W-V-L-G-C-P-T-C-D-E-N-I-A-I-D-A-A-L-E-R-A-S-V-V-L-P-L-A-V-A-G-D-F-D-G-A-M-K-K-L-H-T-V-V"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-K-R-W-Y-V-V-H-A-Y-S-G-F-E-K-S-V-A-Q-A-L-R-D-R-I-S-R-I-E-I-Q-D-R-F-G-D-V-L-V-P-A-E-E-V-V-E-M-R-S-G-Q-K-R-R-S-E-H-K-F-F-P-G-Y-V-L-I-Q-I-E-T-Y-Y-E-G-G-V-P-R-I-D-N-E-C-W-H-L-V-K-E-T-P-K-V-M-G-F-I-G-G-T-A-D-R-P-L-P-I-S-S-D-E-A-D-V-I-L-R-R-V-Q-D-G-A-E-K-P-R-P-K-V-L-F-E-P-G-Q-M-V-R-V-I-D-G-P-F-N-D-F-D-G-L-V-E-E-V-N-Y-E-K-N-R-L-R-V-A-V-L-I-F-G-R-P-T-P-V-D-L-D-F-G-Q-V-Q-K-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-T-A-Y-I-K-L-Q-V-K-A-G-Q-A-S-P-S-P-P-V-G-P-A-L-G-Q-R-G-L-N-I-M-D-F-C-K-A-F-N-A-G-T-Q-K-I-E-Q-G-L-P-I-P-V-V-I-T-A-Y-S-D-R-T-F-T-F-I-T-K-S-P-P-A-S-I-L-L-K-K-I-V-G-I-Q-S-G-S-K-R-P-N-T-E-K-V-G-K-V-T-R-K-Q-L-E-D-I-A-K-T-K-E-L-D-M-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-V-V-E-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-V-F-Q-K-Q-E-V-V-K-E-L-A-G-V-A-T-K-A-H-S-L-I-V-A-E-Y-A-G-I-T-V-P-Q-M-T-A-M-R-K-Q-A-R-E-S-G-V-Y-L-K-V-V-K-N-K-L-A-A-R-A-L-G-D-T-E-Y-A-V-I-K-E-K-L-I-G-P-L-L-Y-A-F-S-L-E-D-P-G-A-A-G-R-L-I-K-E-F-S-K-K-H-D-K-L-K-S-K-A-V-S-L-G-G-V-L-Y-P-A-G-H-V-D-V-L-A-S-L-P-T-R-L-Q-A-L-A-M-L-A-R-V-L-S-E-P-V-T-L-F-A-R-A-I-K-A-M-A-D-D-K-S-E-T-F-A-V-S-S-P-E-T-S-E-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-L-T-N-E-K-I-V-E-A-I-A-E-K-S-I-M-E-V-M-E-L-V-K-A-I-E-D-R-F-G-V-S-A-A-A-P-V-M-V-S-G-S-A-A-A-A-A-P-V-E-E-Q-T-E-F-T-V-T-L-K-E-A-G-A-K-K-V-E-V-I-K-A-V-R-A-V-T-G-L-G-L-K-E-A-K-D-L-T-E-A-G-G-I-L-K-E-A-V-S-K-E-E-A-E-K-V-K-K-E-L-E-A-A-G-A-T-V-E-V-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-G-S-T-P-Q-R-N-V-L-P-D-P-K-Y-G-S-E-T-I-A-R-F-I-N-M-V-M-K-S-G-K-K-S-V-A-E-K-I-V-Y-G-A-M-N-V-I-G-E-K-N-S-N-A-I-E-L-L-Q-K-A-L-D-N-V-S-P-A-V-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-A-S-R-R-M-A-L-A-M-R-W-L-I-D-S-S-R-K-R-G-E-N-S-M-P-R-K-L-A-A-E-L-L-D-A-S-E-S-R-G-G-A-I-K-K-R-D-E-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-Q-I-S-D-T-A-K-S-H-F-L-K-L-I-Q-R-E-G-V-P-G-M-G-V-R-L-S-A-V-D-P-G-T-P-R-A-D-A-R-L-E-F-A-D-P-S-E-L-V-G-D-E-W-L-I-D-C-G-D-F-T-L-Y-V-A-S-A-S-V-A-W-L-D-G-A-E-I-D-Y-V-T-Q-A-T-G-S-Q-Q-L-I-I-K-A-P-K-I-K-G-Q-E-L-S-Q-V-A-S-L-V-E-R-V-C-W-V-V-E-N-E-I-N-P-Q-L-A-S-H-G-G-R-V-E-V-Q-E-V-S-A-E-G-V-V-L-L-R-F-G-G-G-C-H-G-C-G-M-A-D-V-T-L-K-Q-G-V-E-K-T-L-M-D-R-V-H-G-V-I-A-V-R-D-A-T-D-H-S-T-G-A-A-P-Y-I-S-R-D-F-S-P"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-K-F-F-R-R-R-K-F-C-K-F-T-A-E-G-I-K-E-I-D-Y-K-D-L-N-T-L-R-Q-Y-L-T-E-N-G-R-I-V-P-S-R-V-T-G-T-K-S-K-Y-Q-R-Q-L-T-T-A-V-K-L-A-R-F-L-A-L-I-P-Y-T-D-N-H-D-I"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-L-I-L-L-Q-K-V-A-N-L-G-A-L-G-D-K-V-T-V-K-P-G-Y-G-R-N-F-L-L-P-N-G-V-A-V-P-A-T-E-A-N-L-A-A-F-Q-A-K-R-A-E-Y-E-A-K-A-K-S-E-L-D-Q-A-Q-A-R-A-A-K-F-E-G-A-S-V-T-V-S-A-H-A-S-T-E-G-K-L-Y-G-S-V-G-A-R-D-I-A-E-A-F-T-A-V-G-L-P-L-E-K-K-E-V-I-L-G-E-G-A-F-R-L-I-G-E-Y-D-V-L-L-H-L-H-A-D-V-E-S-T-V-K-V-I-V-Q-G-V-P"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-G-D-C-N-I-S-T-S-D-N-K-Q-N-R-K-N-H-E-I-R-V-P-R-V-R-V-I-G-S-D-G-E-M-I-G-V-L-S-R-D-E-A-L-A-M-A-E-K-E-G-L-D-L-V-E-I-Q-P-Q-A-D-P-P-V-C-K-V-M-N-F-G-K-F-K-F-E-Q-Q-K-K-A-N-E-A-K-K-K-T-K-Q-V-E-I-K-E-L-K-F-R-P-V-T-D-E-G-D-Y-Q-I-K-L-R-N-M-R-R-F-L-E-E-G-D-K-V-K-I-N-I-R-F-R-G-R-E-M-S-H-Q-E-L-G-R-Q-M-A-A-R-I-E-M-D-L-G-D-D-V-V-I-E-S-R-P-R-L-E-G-R-Q-M-V-M-M-V-A-P-R-K-K-S"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-Q-A-R-R-R-H-K-K-I-L-S-L-A-K-G-Y-Y-N-A-R-R-K-V-F-R-V-A-K-Q-A-V-I-K-A-Q-Q-Y-A-Y-I-G-R-K-Q-K-K-R-N-F-R-S-L-W-I-V-R-I-N-A-A-A-R-M-N-G-L-S-Y-S-R-F-M-N-G-I-L-K-C-G-I-T-L-D-R-K-M-L-A-D-I-A-V-H-D-P-A-G-F-T-A-L-A-E-K-A-K-T-M-L-A-A"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-E-M-V-E-R-L-F-D-E-V-G-L-N-K-R-E-A-K-E-F-V-D-A-F-F-D-L-L-R-D-A-L-E-Q-G-K-E-I-K-L-S-G-F-G-N-F-E-L-R-C-K-N-Q-R-P-G-R-N-P-K-T-G-E-E-I-P-I-S-A-R-T-V-V-T-F-R-S-G-Q-K-L-K-E-R-V-D-A-Y-V-G-S-R-Q"} +{"text": "### FUNCTION Represses an operon that probably comprises itself, PD_1892, PD_1893, PD_1894 and blh Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon ### SEQUENCE -M-V-N-E-M-R-D-N-T-V-P-H-M-T-R-E-D-M-E-K-R-A-N-E-V-A-N-L-L-K-T-L-S-H-P-V-R-L-M-L-V-C-T-L-V-E-G-E-F-S-V-G-E-L-E-Q-Q-I-G-I-G-Q-P-T-L-S-Q-Q-L-G-V-L-R-E-S-G-I-V-E-T-R-R-N-I-K-Q-I-F-Y-R-L-T-E-A-K-A-A-Q-L-V-N-A-L-Y-T-I-F-C-T-Q-E-K-Q-A"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-R-G-P-I-F-L-N-V-G-I-S-Y-G-L-P-R-T-K-L-P-A-A-V-S-F-R-K-W-V-A-A-T-L-Q-G-R-I-R-K-A-D-L-A-I-R-I-V-D-E-K-E-G-R-A-L-N-Y-H-Y-R-N-K-D-Y-A-T-N-V-L-S-F-P-A-Q-L-P-E-P-F-P-K-A-L-K-I-P-L-L-G-D-I-V-M-C-A-P-V-I-A-R-E-A-T-E-Q-G-K-S-L-S-A-H-Y-A-H-L-T-V-H-G-T-L-H-L-L-G-W-N-H-E-D-H-Q-E-A-D-A-M-E-Q-L-E-R-E-I-L-A-N-L-G-I-S-D-P-Y-L-G-E-Y"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Y-C-L-F-C-Q-H-T-D-T-R-V-I-D-S-R-V-S-E-D-G-A-T-I-R-R-R-R-E-C-E-A-C-G-E-R-F-S-T-L-E-T-I-E-L-K-L-P-V-I-I-K-K-D-G-G-R-E-A-F-D-G-R-K-L-R-T-S-F-D-R-A-L-Q-K-R-P-V-A-E-E-R-I-E-M-A-M-R-A-V-I-H-R-L-R-M-A-G-E-R-E-V-P-S-I-V-V-G-E-C-V-M-A-E-L-R-K-L-D-H-V-G-Y-V-R-F-A-S-V-Y-R-S-F-Q-D-V-A-D-F-R-E-E-I-E-K-L-E-S-E-L-L-V-S-R-E-Q-L-P-L-L-E-A-V-M-E-S-I-G-H-P-S-I-D-Q-G-G"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-S-H-Y-E-G-D-L-R-P-A-G-A-R-F-V-I-V-C-S-R-W-N-A-R-I-T-D-A-L-V-A-G-A-C-H-S-L-V-D-N-G-V-P-D-D-A-V-D-V-V-R-V-P-G-A-W-E-I-P-I-V-A-N-L-L-A-Q-A-G-Q-H-A-A-I-I-A-L-G-C-V-V-R-G-D-T-R-H-Y-E-H-V-A-D-L-C-A-E-G-M-M-S-V-Q-M-Q-T-G-V-P-V-L-N-G-V-L-A-V-E-C-I-K-D-A-E-M-R-A-G-G-S-H-G-N-K-G-A-E-T-A-L-A-A-L-E-M-V-S-L-L-E-K-L-P"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-K-V-S-G-G-G-P-C-S-R-R-R-D-G-V-D-P-A-L-R-S-R-A-R-R-R-A-L-Q-A-V-Y-A-W-Q-I-S-G-G-V-A-K-Q-V-I-A-H-F-A-H-E-Q-A-Y-E-V-A-D-L-V-Y-F-E-D-L-V-E-G-V-L-T-H-C-A-E-L-D-E-K-L-T-P-Y-L-D-R-T-I-E-E-V-D-A-I-E-R-A-V-L-R-L-G-A-Y-E-L-L-Y-R-Q-D-V-P-Y-R-V-V-I-N-E-A-I-M-T-A-K-R-F-G-S-K-Y-G-H-T-Y-V-N-G-V-L-D-R-A-A-L-A-L-R-K-V-E-V-L-G"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-M-K-C-L-L-I-A-T-G-Q-H-V-P-T-W-V-A-Q-G-F-A-E-Y-H-R-R-L-S-Y-W-L-P-L-E-L-V-E-I-E-P-S-M-R-G-K-N-H-D-P-Q-R-A-I-E-D-E-G-R-R-V-M-A-A-L-P-K-Q-P-Y-A-V-T-L-D-V-K-G-K-P-L-N-S-E-Q-L-A-Q-R-M-E-H-W-R-G-L-G-R-N-L-V-F-L-I-G-G-P-E-G-H-S-Q-E-V-L-N-I-S-N-E-R-W-S-L-G-P-L-T-L-P-H-M-L-V-R-L-I-V-V-E-Q-L-Y-R-A-A-T-I-L-T-N-H-P-Y-H-R-G-K"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-N-A-L-Q-W-S-F-R-A-Q-C-L-T-G-F-L-F-C-T-G-L-L-A-Y-A-I-F-L-Q-L-H-Q-G-L-E-P-C-P-L-C-I-F-Q-R-I-A-F-A-V-L-G-I-L-F-L-I-A-G-L-Y-N-S-S-N-V-Y-T-R-K-A-Y-G-L-L-I-F-L-T-A-I-I-G-T-G-I-A-G-R-H-V-W-V-Q-L-M-P-H-N-T-I-S-S-C-G-S-P-L-S-F-L-S-E-T-M-G-P-F-E-V-F-R-T-V-L-T-G-T-S-N-C-G-N-I-D-W-R-F-L-G-L-S-M-P-M-W-S-M-F-W-F-V-A-L-A-L-L-G-L-L-V-G-F-K-A-E-R-R-K-P-L-F-S"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-P-D-G-Y-R-P-N-V-G-I-V-L-I-R-R-D-G-Q-V-F-W-G-R-R-V-R-R-D-G-W-Q-F-P-Q-G-G-M-H-S-D-E-T-P-V-E-A-M-Y-R-E-L-N-E-E-T-G-L-L-P-E-H-V-Q-L-V-G-A-T-P-G-W-L-R-Y-R-L-P-S-Q-A-V-R-C-N-R-S-Q-M-C-I-G-Q-K-Q-V-W-F-L-L-Q-L-I-G-D-E-S-H-V-Q-L-D-Q-S-E-N-P-E-F-D-H-W-R-W-V-S-F-W-Y-P-I-E-H-V-V-M-F-K-R-S-V-Y-A-R-A-L-C-Q-L-A-S-L-A-Q-Q-V-V-G-L-E-V-G-T-M-P-Q-Y-V-Q-D-I-C-L-L-N-V-G-Y-K-H-L-P-N-W-V-S-R-Y"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-S-E-L-L-L-I-A-V-V-A-L-V-V-L-G-P-E-R-L-P-K-A-A-R-F-A-G-L-L-V-R-R-A-R-T-Q-W-E-S-I-K-Q-E-L-E-R-E-L-E-A-E-A-L-K-R-N-L-Q-N-A-Q-Q-V-I-H-D-A-Q-A-Q-L-Q-S-N-Q-Q-D-M-D-I-Q-N-S-I-S-I-L-H-E-Q-T-K-R-D-I-H-P-D-H-D-T-N-T-L-E-P-S-T-A-V-H-H-V-H-V-P-P-P-S-T-S-T-H-G-N-N-G-Q-E-K-S-Q"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-L-L-H-W-L-V-V-L-V-I-V-L-L-V-F-G-T-K-R-L-A-N-G-A-K-D-I-G-S-A-I-K-E-F-K-K-S-L-H-E-D-D-K-P-T-D-Q-L-G-S-T-S-Q-S-T-A-S-G-P-Q-Q-D-H-G-K-H"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-P-K-R-S-P-P-D-T-S-P-V-A-R-F-E-Q-S-L-Q-E-L-E-Q-L-V-Q-N-M-E-T-G-A-L-S-L-E-Q-S-L-G-A-Y-E-R-G-I-A-L-Y-R-E-C-H-Q-A-L-E-Q-A-Q-L-R-V-R-I-L-S-D-P-M-H-P-D-D-G-E-P-F-D-P-S-L-V-S-T-S-Q"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-I-L-T-K-R-Q-A-H-L-K-S-D-D-V-D-L-A-V-K-S-L-L-E-M-M-G-G-A-L-S-G-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-P-P-R-C-G-R-N-P-K-T-G-E-S-V-A-L-P-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-E-R-V-A-S-V-V-P-L-G-E-C-G-D-I-T-E"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-L-V-T-G-G-K-Q-Y-R-V-V-Q-G-E-T-L-R-V-E-K-L-D-V-E-T-G-G-D-V-T-F-N-S-V-L-L-M-G-G-S-D-G-I-H-V-G-E-A-L-K-D-A-S-V-T-A-K-V-V-A-H-G-R-A-R-K-V-R-I-I-K-F-R-R-R-K-H-H-M-K-H-Q-G-H-R-Q-Y-Y-T-E-I-Q-I-T-G-I-S-G-P-A-K-Q"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-N-N-K-H-P-K-N-K-A-K-S-T-T-T-P-K-T-I-A-L-N-K-R-A-R-H-E-Y-H-L-I-E-R-H-E-A-G-L-E-L-Q-G-W-E-V-K-A-I-R-A-G-R-A-N-L-G-D-G-Y-A-Y-V-R-D-G-E-I-F-L-I-G-A-Q-I-T-P-L-I-Q-A-S-T-H-V-V-A-N-D-R-R-T-R-K-L-L-L-H-R-H-Q-I-D-T-L-I-G-R-V-Q-R-E-G-F-T-L-V-P-T-A-M-Y-W-S-K-N-R-V-K-M-E-I-A-L-A-K-G-K-Q-A-H-D-K-R-H-A-E-K-E-R-E-W-Q-R-D-K-Q-R-I-M-R-A-H-N-R-N-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-Q-D-H-P-E-C-D-S-E-E-L-T-Q-N-S-P-E-T-D-P-L-K-V-E-V-E-T-L-R-G-E-I-A-S-I-K-A-D-V-L-R-E-R-A-E-L-E-N-Q-R-K-R-L-I-R-D-V-E-Q-A-R-K-F-A-N-E-K-L-L-G-E-L-L-P-V-F-D-S-L-D-A-G-L-T-A-S-G-S-E-P-S-P-L-R-D-G-L-E-L-T-Y-K-Q-L-L-K-V-A-I-D-N-G-L-M-L-L-D-P-V-G-Q-L-F-N-P-E-H-H-Q-A-I-S-Q-T-E-V-T-D-V-E-P-G-H-V-I-Q-V-F-Q-K-G-Y-L-L-N-E-R-L-L-R-P-A-L-V-V-V-A-K-Q-D"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-S-P-I-T-T-L-L-I-G-I-A-M-S-T-D-A-F-A-A-A-I-G-K-G-A-A-I-G-K-P-R-L-R-D-A-L-Y-V-A-V-I-F-G-V-I-E-T-A-T-P-I-A-G-W-L-L-G-Q-V-A-S-H-Y-I-A-T-F-D-H-W-I-A-F-G-L-L-G-G-L-G-I-H-M-I-V-N-G-L-K-N-N-G-N-T-C-K-D-N-A-D-T-H-N-R-N-S-R-W-L-T-L-A-A-T-A-L-A-T-S-I-D-A-A-A-I-G-I-S-M-A-F-L-D-I-H-I-G-I-V-A-A-V-I-G-L-C-T-F-T-M-V-I-F-G-V-M-L-G-R-V-L-G-T-F-V-G-N-R-A-E-I-V-G-G-I-I-L-I-I-V-G-S-T-I-L-Y-E-H-L-S-N-T-G"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-D-E-I-T-N-G-A-A-K-P-T-E-A-I-S-G-P-T-F-T-I-E-K-I-Y-I-K-D-V-S-F-E-A-P-N-S-P-A-V-F-N-E-A-G-Q-P-E-L-Q-L-N-L-N-Q-R-V-Q-R-L-N-E-N-A-F-E-L-V-L-H-V-T-L-T-C-T-A-A-G-K-T-A-Y-V-V-E-V-Q-Q-A-G-V-F-G-L-F-G-L-D-Q-H-A-I-G-V-L-L-G-T-Q-C-P-N-I-L-F-P-Y-V-R-S-L-V-S-D-L-I-Q-I-G-G-F-P-P-F-Y-L-Q-P-I-N-F-D-A-L-Y-A-E-T-L-R-Q-R-A-Q-N-E-K-E-G-S-Q-I-S-S-Q-P-A-G-N-A"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-R-G-N-I-A-Q-L-M-Q-Q-A-Q-K-M-Q-E-N-L-Q-R-A-Q-E-E-L-A-K-L-E-V-T-G-S-A-G-G-S-M-V-S-V-I-L-S-G-T-K-E-C-R-K-V-R-I-D-P-S-I-L-N-D-Q-E-M-I-E-D-L-I-A-A-A-F-N-D-A-S-N-K-V-D-A-E-S-K-E-R-M-G-S-A-T-L-G-M-S-L-P-P-G-F-K-L-P-F"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-T-H-L-L-E-Q-L-I-D-A-F-R-I-L-P-G-V-G-Q-K-T-A-Q-R-M-A-Y-H-M-L-E-R-E-R-E-G-G-Q-R-L-A-D-V-L-S-R-A-I-E-K-I-G-H-C-T-E-C-R-D-F-S-E-T-K-I-C-A-I-C-A-N-S-S-R-D-R-H-Q-L-C-V-V-E-S-P-P-D-R-L-A-I-E-Q-A-T-G-Y-R-G-L-Y-F-I-L-Q-G-R-L-S-P-L-D-G-I-G-P-H-E-L-G-L-D-H-L-G-Q-R-L-A-A-G-E-V-T-E-L-I-I-A-T-N-A-T-V-E-G-E-T-T-A-H-Y-L-A-L-L-A-R-Q-H-G-I-R-P-S-R-L-A-Q-G-L-P-L-G-G-E-L-E-Y-L-D-R-G-T-L-S-H-A-F-G-T-R-T-E-V-V"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-L-R-G-V-L-T-S-K-T-P-P-W-L-V-V-D-V-C-G-V-G-Y-E-L-E-V-P-M-S-T-F-C-E-L-P-D-V-G-Y-E-V-N-L-F-T-H-Y-T-Q-K-D-D-S-A-A-L-Y-G-F-L-S-E-S-E-R-R-L-F-R-H-L-Q-R-V-S-G-I-G-T-K-I-A-L-A-I-L-S-S-V-S-V-D-T-F-A-G-L-I-Q-A-G-D-A-N-A-L-T-V-I-P-G-V-G-K-K-T-A-E-R-M-L-V-E-L-R-D-R-A-A-D-F-N-N-G-I-S-T-S-G-K-L-N-L-D-T-V-S-E-A-A-L-A-L-Q-Q-L-G-Y-K-P-A-E-A-A-R-M-A-R-D-A-G-T-E-S-D-D-V-A-I-V-I-K-K-A-L-Q-T-V-L-R"} +{"text": "### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-S-R-E-Q-A-F-E-M-L-I-K-I-L-C-K-T-D-S-T-D-D-M-K-L-I-L-E-C-I-L-T-R-S-E-M-E-D-L-I-D-R-I-R-I-Y-N-E-L-L-N-T-S-N-S-Q-R-E-V-A-S-K-L-G-V-S-I-T-K-I-T-R-G-A-A-N-L-Q-D-N-N-I-K-D-F-L-R-K-K-I-S-Y"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-T-T-F-T-A-K-N-E-T-V-Q-R-D-W-Y-L-V-D-A-E-G-K-T-L-G-R-L-A-T-E-L-A-R-R-L-L-G-K-T-K-P-V-Y-T-P-H-V-D-T-G-D-Y-L-V-V-I-N-A-E-K-V-V-V-T-G-K-K-L-T-D-K-Y-Y-H-R-F-T-G-Y-V-G-N-L-K-S-E-S-L-G-Q-A-L-Q-R-H-P-E-R-V-L-E-I-A-V-K-G-M-L-P-K-G-P-L-G-R-A-M-Y-R-K-L-K-V-Y-T-G-S-K-H-P-H-T-A-Q-Q-P-Q-V-L-D-I"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-V-E-D-C-L-E-V-V-N-N-R-F-E-L-V-M-M-A-S-K-R-A-R-Q-L-A-N-G-V-P-P-L-I-E-N-T-N-S-E-D-K-P-T-V-M-A-L-R-E-I-A-A-R-K-I-N-S-K-M-I-D-E-I-E-K-A-E-R-E-R-A-E-R-E-A-M-E-W-A-A-A-E-V-V-A-D-E-D-M-S-K-S-D-D"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-A-V-V-W-W-Q-S-L-L-L-V-M-L-G-G-A-F-G-S-G-L-R-F-V-I-G-S-C-L-L-Q-R-F-G-A-G-F-P-W-G-T-L-A-V-N-L-I-G-S-F-V-A-G-F-L-L-I-W-V-D-K-R-G-S-A-G-W-S-W-R-M-L-L-I-V-G-L-I-G-G-L-T-T-F-S-S-L-M-V-E-C-L-V-F-V-R-S-E-R-S-L-I-V-G-F-Y-L-C-I-T-L-L-F-G-L-L-F-V-F-L-G-A-R-L-G-A-F-V-C-D-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-C-I-E-F-E-G-T-V-S-E-T-L-P-N-T-T-F-R-I-K-L-E-S-G-H-E-V-T-A-H-I-S-G-R-M-R-K-N-Y-I-R-I-L-T-G-D-R-V-K-I-E-M-T-A-Y-D-L-T-K-G-R-I-I-Y-R-M-K"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-Q-K-T-V-H-D-Q-D-N-A-L-L-L-E-T-G-N-T-K-V-A-P-P-P-R-Y-Q-V-L-L-L-N-D-D-Y-T-P-M-D-F-V-I-V-V-L-Q-Q-F-F-A-M-D-L-K-K-A-T-Q-V-M-L-H-V-H-T-R-G-R-G-V-C-G-F-Y-T-R-E-V-A-E-S-K-V-A-Q-V-N-E-F-S-R-I-H-Q-H-P-L-L-C-T-M-K-Q-A"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-L-E-H-E-L-T-V-T-N-K-L-G-L-H-A-R-A-T-A-K-L-V-Q-T-M-S-K-F-Q-S-N-T-T-L-S-T-K-G-R-E-V-N-A-K-S-I-M-G-V-M-L-L-A-A-S-Q-G-T-V-I-R-V-R-I-D-G-E-D-E-H-T-A-M-Q-A-L-S-E-L-F-E-N-R-F-N-E-D-T"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-R-G-I-N-K-V-I-L-V-G-N-L-G-N-D-P-D-I-K-Y-T-Q-G-G-M-T-I-T-T-I-S-L-A-T-T-S-V-R-K-D-K-D-G-N-T-Q-E-R-T-E-W-H-R-V-K-F-F-G-K-L-G-E-I-A-G-E-Y-L-R-K-G-S-Q-C-Y-I-E-G-S-I-R-Y-D-K-F-T-G-Q-D-G-Q-E-R-Y-V-T-E-I-V-A-D-E-M-Q-M-L-G-G-R-S-D-G-G-G-M-G-G-G-G-E-R-P-Q-R-Q-T-S-Q-R-Q-D-Y-A-P-R-R-Q-T-R-Q-P-S-Q-S-P-Q-S-S-P-P-P-M-D-D-F-A-D-D-D-I-P-F"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-N-W-R-W-L-L-L-V-L-A-A-L-L-A-W-L-Q-H-R-F-W-F-G-P-G-N-S-G-E-V-R-M-L-Q-V-Q-I-V-Q-Q-H-Q-E-N-E-R-L-R-Q-R-N-A-S-L-A-A-E-V-K-N-L-K-D-G-D-A-A-I-E-E-R-A-R-S-E-L-G-M-I-K-P-G-E-I-F-Y-R-V-V-E-D-I-P-V-P-L-P-N-D-T-S-A-D-H-G-V-D-L-S-Q-P-R-R-E-K-R"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-V-A-E-L-P-V-V-E-S-D-R-R-L-I-W-I-D-L-E-M-T-G-L-D-T-H-R-D-S-I-I-E-I-A-T-V-V-T-D-A-Q-L-N-V-L-A-E-G-P-E-F-A-I-S-H-P-L-N-V-L-E-A-M-D-E-W-N-R-N-Q-H-R-H-S-G-L-W-Q-R-V-L-N-S-E-I-Q-H-A-Q-A-E-A-S-T-I-A-F-L-Q-Q-W-V-K-I-G-A-S-P-M-C-G-N-S-I-C-Q-D-R-R-F-L-H-R-Q-M-P-C-L-E-R-Y-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-A-G-C-W-S-P-S-I-L-D-G-V-V-K-T-S-S-H-T-A-L-S-D-I-Y-D-S-I-A-E-L-R-H-Y-R-K-S-M-G-T-F-A-G-L-S-V-V"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-E-L-I-D-G-V-A-A-A-A-N-L-S-K-V-E-A-G-R-A-I-D-A-V-V-N-E-I-T-E-A-L-K-E-G-D-S-V-T-L-V-G-F-G-T-F-Q-V-R-Q-R-A-E-R-P-G-R-N-P-K-T-G-E-P-I-M-I-A-A-S-N-N-P-S-F-K-P-G-K-A-L-K-D-A-V-K-S-S-A-G"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-L-A-I-Q-K-H-V-W-I-G-L-Q-S-I-Y-G-I-G-R-T-R-S-R-K-V-C-D-A-A-N-V-A-I-Y-T-K-I-R-D-L-S-E-S-E-I-E-R-L-R-V-E-V-G-K-Y-V-I-E-G-D-L-R-R-E-V-G-M-A-I-K-R-L-M-D-L-N-C-Y-R-G-L-R-H-R-R-C-L-P-L-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-K-A-I-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-S-L-R-L-N-D-L-K-P-A-L-G-A-S-S-S-R-A-R-V-G-R-G-I-G-S-G-L-G-K-T-A-G-R-G-H-K-G-S-F-A-R-K-G-G-G-K-I-K-P-G-F-E-G-G-Q-T-P-M-Q-R-R-L-P-K-I-G-F-R-S-R-S-V-A-N-T-A-E-V-L-S-Y-K-L-D-N-L-E-P-G-E-I-D-F-A-S-L-R-L-A-K-L-V-P-S-T-A-K-K-A-K-I-V-K-K-G-R-L-T-K-V-F-V-L-K-G-I-E-S-T-A-G-A-R-A-M-I-E-A-T-G-G-S-F-Q-E"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-E-E-R-S-Q-R-S-R-D-R-S-R-E-E-K-I-D-D-G-M-I-E-K-L-V-A-V-N-R-V-S-K-T-V-K-G-G-R-Q-F-T-F-T-A-L-T-I-V-G-N-G-E-G-S-V-G-F-G-Y-G-K-A-R-E-V-P-V-A-I-Q-K-S-M-E-Y-A-R-K-R-M-S-N-V-S-L-N-N-G-T-L-W-H-P-V-K-A-N-H-G-A-A-S-V-F-M-K-P-A-S-E-G-T-G-V-I-A-G-G-A-M-R-A-V-L-E-A-V-G-V-K-N-V-L-A-K-A-I-G-S-R-N-P-I-N-L-V-R-A-T-L-K-G-L-E-D-M-Q-S-P-T-H-I-A-L-K-R-G-K-N-V-R-D-F-S-H-G-S"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-I-G-K-N-V-A-R-L-R-R-A-K-S-T-R-L-H-I-R-K-L-G-V-P-R-L-S-V-L-R-T-G-R-H-L-Y-A-Q-I-F-T-A-D-G-S-K-V-I-A-A-A-N-T-L-Q-S-Q-V-K-G-G-L-K-N-G-K-N-S-L-A-A-I-K-V-G-K-L-I-A-E-R-A-R-A-V-G-V-D-R-I-A-F-D-R-S-G-Y-L-Y-H-G-R-I-K-I-L-A-D-A-A-R-D-A-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-K-P-I-S-I-P-K-G-V-E-V-S-V-Q-S-D-M-L-T-V-K-G-V-K-G-V-L-T-F-P-K-S-D-N-V-N-V-V-M-D-G-D-I-L-T-L-S-A-N-D-H-S-H-V-S-L-A-G-T-V-R-A-I-L-S-N-M-I-K-G-V-S-I-G-F-E-R-K-L-E-L-V-G-V-G-Y-R-A-S-M-Q-G-K-D-L-N-L-S-L-G-F-S-H-P-L-L-F-V-P-P-E-G-I-N-L-L-T-P-S-Q-T-E-V-V-V-Q-G-I-D-K-Q-R-V-G-E-V-A-A-K-I-R-N-F-R-P-P-E-P-Y-K-G-K-G-L-K-Y-A-T-E-A-I-M-R-K-E-A-K-K-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-T-D-P-I-A-D-M-L-V-R-I-K-N-A-A-S-V-G-K-P-N-V-R-F-P-F-S-K-V-K-L-A-I-A-L-V-L-K-N-E-G-Y-I-F-D-A-K-V-I-Q-S-D-N-S-K-S-D-I-E-V-V-L-K-Y-F-E-G-R-P-V-I-R-I-L-K-R-V-S-R-S-G-L-R-K-Y-C-G-K-A-E-L-P-E-V-L-G-G-L-G-V-S-I-I-S-T-S-K-G-I-M-T-D-S-K-A-R-E-S-G-V-G-G-E-V-L-C-F-V-A"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-I-S-M-I-N-R-D-L-K-R-K-R-L-A-K-K-F-A-D-K-R-L-S-L-K-K-V-I-S-S-Y-A-S-S-Y-E-E-K-I-E-A-S-C-K-L-Q-K-L-P-R-D-S-S-P-T-R-L-R-N-R-C-E-I-S-G-R-P-R-G-V-Y-C-K-F-G-L-G-R-N-K-L-R-E-A-A-M-R-G-D-I-P-G-L-R-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-R-L-E-N-M-Y-K-K-E-V-V-P-A-L-I-K-R-F-G-Y-S-N-P-M-A-V-P-R-L-V-K-I-T-L-N-M-G-V-G-E-A-A-T-N-K-K-V-L-E-N-A-L-A-D-M-A-K-I-S-G-Q-K-P-I-V-T-K-S-R-I-S-V-A-S-F-K-I-R-N-G-W-P-I-G-C-K-T-T-L-R-R-S-K-M-Y-E-F-L-D-R-L-I-N-I-S-L-P-C-V-R-D-F-R-G-I-P-P-R-S-F-D-G-R-G-N-F-N-M-G-V-K-E-Q-V-V-F-P-E-I-D-F-D-A-V-D-A-I-R-G-M-D-I-A-I-T-T-T-A-N-S-D-A-E-A-K-A-L-L-D-A-F-N-F-P-F-R-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-S-R-I-K-K-G-D-Q-V-I-V-I-A-G-K-D-K-G-K-Q-G-E-I-I-R-I-D-G-H-R-V-V-V-S-N-V-N-F-V-K-R-H-T-K-P-N-P-Q-R-G-I-S-G-G-L-I-D-R-E-A-P-I-H-V-S-N-I-K-I-L-N-P-M-T-G-K-G-D-R-V-G-F-K-I-L-G-D-G-C-K-L-R-I-F-R-S-T-G-E-V-I-G-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-Y-L-G-V-A-D-N-S-G-A-K-E-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-S-I-G-D-V-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-E-V-Y-D-A-V-V-V-R-T-R-S-G-V-R-R-P-D-G-S-L-I-R-F-D-G-N-A-A-V-L-L-N-N-K-Q-E-P-I-G-T-R-V-F-G-P-V-T-R-E-L-R-S-E-K-L-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-M-N-D-N-N-E-R-K-P-L-R-T-I-K-G-L-V-I-S-N-K-M-Q-K-T-V-T-V-L-V-E-R-Q-I-K-H-A-L-Y-G-K-Y-I-K-R-S-T-K-L-H-A-H-D-A-D-D-L-C-N-E-G-D-V-V-L-M-T-E-V-A-P-I-S-K-T-K-N-W-R-V-V-E-I-V-A-R-S-D"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-Y-R-K-M-H-K-G-R-N-C-G-L-S-W-N-A-N-V-V-S-F-G-Q-Y-G-L-R-A-T-A-H-G-Q-L-T-A-R-Q-I-E-A-A-R-R-S-I-S-R-Y-V-K-R-G-G-K-L-L-I-R-V-F-P-D-K-P-I-T-K-K-P-I-E-V-R-M-G-S-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-R-M-I-Y-E-I-E-G-V-S-E-D-V-A-R-E-A-F-R-L-A-A-S-K-L-S-V-T-T-A-F-V-V-R-T-V-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-S-A-I-L-R-G-A-R-V-S-P-Q-K-A-R-L-V-A-A-Q-V-R-G-L-S-A-D-S-A-V-N-L-L-R-F-S-S-K-K-A-A-C-L-I-K-K-V-V-E-S-A-I-A-N-A-E-N-N-H-G-S-N-I-D-D-L-R-I-N-T-I-I-V-D-E-G-R-M-L-K-R-F-M-A-R-A-K-G-R-S-S-R-I-V-K-R-S-S-H-I-T-V-V-V-G-P-A-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-T-K-K-G-P-F-F-D-H-H-L-I-K-K-V-E-S-A-A-G-S-K-R-P-I-K-T-C-S-R-R-S-V-I-L-P-Q-M-V-G-H-T-I-A-I-H-N-G-K-N-Y-H-P-V-V-I-N-E-N-M-V-G-H-K-L-G-E-F-S-I-T-R-V-F-K-G-H-C-G-D-K-K-S-G-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-S-S-C-E-K-I-F-G-V-L-R-S-P-R-V-S-E-K-S-S-R-L-Q-E-I-S-N-V-Y-V-F-E-V-S-S-D-A-T-K-I-D-V-K-N-A-V-E-R-L-F-D-V-K-V-G-V-V-R-V-L-N-V-K-G-K-S-K-S-F-R-N-R-G-G-S-R-S-G-W-R-K-A-Y-V-R-L-I-D-G-Q-S-I-D-V-A-S-S-V"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-I-T-F-T-I-F-A-Q-S-L-A-F-A-A-L-I-W-I-V-A-T-K-I-W-P-P-L-I-K-V-I-E-E-R-Q-Q-K-I-A-E-G-L-A-A-A-D-L-G-Q-K-E-L-A-Q-A-Q-E-E-I-K-K-T-L-K-N-A-H-K-K-A-N-E-I-I-E-Q-A-H-A-R-A-H-Q-I-I-E-A-A-K-A-E-A-I-A-E-T-N-R-Q-Q-N-L-A-Q-V-E-I-E-A-A-A-K-R-A-R-E-E-L-R-K-H-V-S-I-L-A-V-N-G-A-E-K-L-L-K-R-E-I-D-V-N-T-H-K-M-L-L-D-E-L-A-A-E-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-I-Q-A-L-T-L-A-R-P-Y-A-R-A-A-F-A-I-A-C-E-K-G-K-C-M-Q-W-S-Q-A-L-T-F-S-A-Q-V-A-N-N-P-I-V-A-T-L-L-S-H-P-Q-L-D-H-E-Q-A-A-A-L-L-S-P-E-G-A-D-P-A-Y-I-R-F-L-E-V-I-A-E-A-H-R-L-D-V-L-L-Q-V-A-G-L-Y-E-K-L-R-A-E-A-Q-H-V-I-K-A-K-I-T-S-A-I-E-L-A-P-N-E-L-N-N-I-V-T-A-L-K-K-R-F-D-C-E-I-E-V-T-T-G-V-D-H-S-L-I-G-G-A-V-I-D-T-G-N-V-V-I-D-G-S-I-K-S-K-L-T-R-L-Q-A-S-L-T-H"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-L-Y-L-A-S-R-S-L-C-R-R-Q-L-L-Q-R-L-D-I-P-F-Q-V-I-D-L-E-I-P-E-V-R-R-E-D-E-L-P-Q-D-Y-V-R-R-V-A-Q-E-K-A-Q-V-G-L-A-R-V-G-D-A-F-A-P-K-V-L-G-A-D-T-E-V-V-L-D-G-R-V-F-G-K-P-V-D-L-A-E-A-A-T-M-L-A-A-L-S-G-R-T-H-Q-V-M-T-A-V-S-L-V-A-A-G-G-V-A-A-Q-V-L-V-V-S-E-V-S-F-A-L-L-S-Q-G-Q-I-A-R-Y-V-D-S-G-E-P-M-G-K-A-G-A-Y-A-I-Q-G-R-G-E-C-F-V-S-R-L-V-G-S-Y-S-G-V-M-G-L-P-L-Q-Q-T-A-Q-L-L-A-T-F-E-E-S"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-R-A-P-M-T-L-K-G-V-R-R-L-R-D-E-L-E-H-L-K-S-V-K-R-P-E-I-I-N-A-I-A-E-A-R-A-H-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-Q-Q-S-F-I-E-G-R-I-K-Q-L-E-G-E-L-S-H-A-E-V-I-D-V-A-K-L-N-A-G-T-K-I-V-F-G-A-T-V-T-L-A-D-L-G-T-D-E-E-S-R-Y-Q-I-V-G-D-L-E-A-D-I-K-Q-G-L-V-A-I-S-S-P-V-A-R-A-L-I-G-K-Q-E-G-D-T-I-V-I-E-A-P-A-G-R-R-E-Y-E-V-V-A-V-E-Y-I-S"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-N-Q-I-K-Q-D-A-Q-D-R-M-T-K-S-I-D-A-L-R-N-S-L-A-S-V-R-T-G-R-A-S-P-S-L-L-D-G-I-K-I-K-A-Y-G-T-D-T-P-L-N-Q-V-A-S-I-S-V-S-E-G-R-S-L-V-I-T-V-F-D-K-N-M-S-K-D-V-E-K-A-I-Y-A-S-D-L-G-L-T-P-T-V-V-G-T-L-I-R-L-N-L-P-P-L-T-E-E-R-R-K-E-L-T-K-V-V-H-S-E-G-E-D-T-K-V-A-I-R-N-I-R-R-D-A-N-Q-Q-I-K-D-M-L-K-S-K-E-I-T-E-D-E-V-R-H-G-E-E-D-I-Q-K-L-T-D-K-A-I-K-S-V-D-E-V-V-K-S-K-E-Q-E-L-M-T-V"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-S-D-S-P-T-T-A-H-T-R-L-E-L-P-I-D-I-I-R-I-Q-A-L-L-P-H-R-Y-P-F-L-L-V-D-R-I-L-E-L-D-Q-K-Q-K-R-I-V-A-Q-K-N-V-S-I-N-E-P-F-F-Q-G-H-F-P-E-H-P-V-M-P-G-V-L-I-I-E-A-L-A-Q-A-G-G-V-M-T-Q-L-N-L-S-H-N-G-H-S-S-L-L-F-Y-M-V-R-V-D-N-A-R-F-N-K-Q-V-V-P-G-D-I-L-I-L-D-M-T-M-K-R-R-I-R-N-M-G-C-Y-Y-G-E-A-R-V-N-G-E-V-V-A-C-A-D-I-M-C-A-G-V-K-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-H-K-V-I-M-H-P-L-I-L-L-L-K-I-Y-K-R-L-I-S-P-L-L-G-P-H-C-R-F-E-P-S-C-S-E-Y-A-M-V-A-I-A-R-F-G-T-L-R-G-I-W-L-A-A-R-R-L-A-R-C-H-P-L-Q-L-G-G-H-D-P-V-P-D-N-T-S-T-Q-V-N-P-R-S-H-R-C-T-G-H-H-Q"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-K-K-S-F-Q-R-T-E-R-I-S-V-Q-I-R-R-D-L-G-A-F-V-Q-A-A-V-R-D-H-G-L-P-S-M-S-V-S-D-V-E-V-T-R-D-M-A-H-A-K-V-F-V-T-A-L-Q-A-E-R-S-F-E-A-V-A-G-L-K-A-L-A-R-E-L-R-M-Q-L-A-Q-T-M-R-L-R-F-V-P-E-L-H-F-H-Y-D-D-S-L-D-R-G-E-R-I-D-T-L-L-R-D-L-I-P-P-A-D-A-E-K-D-E-S-G"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-D-K-G-I-E-I-V-N-L-L-A-P-K-V-E-M-L-G-F-D-L-L-G-A-E-Y-L-L-V-P-S-G-A-I-L-R-L-Y-I-D-I-P-F-A-M-Q-P-E-C-M-V-S-I-D-D-C-E-R-V-S-R-E-V-S-A-Y-L-D-L-E-E-P-I-S-G-N-Y-T-L-E-V-S-S-P-G-L-D-R-R-L-F-T-L-E-Q-F-A-R-H-H-N-H-L-V-K-V-G-L-K-L-Q-Q-H-G-S-R-R-L-Q-G-K-I-V-R-V-E-Q-V-G-G-F-V-V-L-L-V-N-G-V-E-L-A-V-D-F-N-N-I-D-K-A-R-I-V-P-D-W-S-A-L-G-L-A-P-L-E-K-S-K-H-D-T-K-K-M-S-Q-G-S-K-K-P-S-N-E-S-A-A-R-Q-A-V-R-G-V-I-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-D-I-P-G-D-L-K-F-L-K-S-H-E-W-V-R-I-E-D-N-N-R-A-I-V-G-V-S-D-H-A-Q-N-L-L-G-D-L-V-Y-V-E-L-P-N-I-G-D-H-L-D-A-G-A-T-A-A-V-I-E-S-V-K-A-A-S-D-I-Y-S-P-V-T-G-K-V-I-E-V-N-T-T-L-S-D-K-P-E-T-I-N-E-D-P-Y-G-E-G-W-I-M-V-I-E-M-Q-A-P-E-E-I-S-N-L-L-S-P-D-D-Y-T-E-V-L-E-S-D-E-H"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-K-L-N-K-S-I-I-A-E-F-E-S-A-Q-I-T-R-Q-V-P-Q-F-S-Q-G-D-T-I-V-V-N-V-K-V-K-E-G-N-R-E-R-L-Q-A-Y-E-G-V-V-I-A-T-K-N-A-G-L-N-S-A-F-T-V-R-K-I-S-H-G-Y-G-V-E-R-V-F-Q-T-H-S-P-I-I-E-S-I-E-I-K-R-R-G-K-V-R-A-A-K-L-Y-Y-L-R-G-L-E-G-K-A-A-R-I-K-E-D-L-A-A-T-A-H-E-K-L-A-R-K-T-V-T-A-K-A-G"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-D-N-E-R-R-I-L-L-G-R-V-V-G-G-F-G-L-R-G-E-I-K-I-E-S-W-T-E-P-R-D-A-I-F-R-Y-Q-P-W-L-L-R-S-P-T-G-T-E-S-M-L-N-G-A-R-G-Y-E-T-G-K-R-L-I-A-T-F-P-G-I-N-D-R-N-G-V-E-A-I-C-G-T-E-I-Y-V-P-R-S-A-L-P-P-P-H-P-D-E-Y-Y-W-V-D-L-E-G-L-Q-V-H-T-L-E-G-V-V-L-G-S-V-S-H-L-F-S-N-G-A-N-D-V-I-V-I-H-G-E-R-E-R-L-I-P-F-V-Q-P-D-Y-V-K-S-V-D-F-E-A-E-R-I-V-V-D-W-D-P-E-F"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-V-P-V-S-V-Y-L-V-N-G-I-K-L-Q-G-T-I-E-S-F-D-Q-F-V-V-L-L-R-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-N-V-R-V-G-P-G-G-G-Y-V-H-S-G-S-D-T-L-Q-I-N-D-D-E-V-E"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-F-I-R-E-F-K-E-F-V-M-R-G-N-V-I-D-L-A-V-A-V-V-I-G-A-A-F-G-K-I-V-T-A-L-V-D-K-I-I-S-P-L-I-G-V-M-V-G-G-I-D-F-S-K-L-S-L-T-L-K-A-A-T-V-D-T-A-G-K-E-V-P-A-V-V-I-G-Y-G-D-F-I-N-T-I-L-Q-F-I-I-I-A-F-A-I-F-I-I-V-K-M-I-N-K-V-I-N-K-Q-P-L-P-P-E-T-P-S-E-D-V-L-L-L-R-E-I-R-D-S-L-K-K"} +{"text": "### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-S-S-H-P-T-K-I-T-F-F-E-F-L-T-P-L-I-T-S-G-Q-K-T-I-T-I-R-D-E-S-E-S-H-Y-V-P-N-T-E-V-E-V-F-T-L-E-T-D-R-K-V-C-D-I-K-I-L-S-V-E-P-L-N-F-D-E-I-N-E-F-H-A-E-Q-E-A-I-E-L-P-K-L-K-Q-L-I-R-E-I-Y-P-N-I-D-K-L-F-V-I-E-Y-E-L-I-K-K"} +{"text": "### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-V-G-M-P-E-I-R-K-P-Q-L-V-K-A-T-M-S-V-I-D-R-V-G-L-H-A-A-S-I-S-L-I-S-K-E-A-G-V-S-T-G-I-I-N-H-Y-F-G-G-K-H-G-L-L-E-E-T-M-R-E-I-L-R-Q-L-S-S-T-I-T-G-K-L-R-A-L-P-A-D-A-H-H-Q-R-I-N-A-I-I-D-G-N-F-V-G-Y-Q-A-E-N-K-V-A-K-T-W-L-A-F-W-S-Y-S-M-H-D-E-Q-L-K-R-L-Q-R-V-N-E-R-R-L-L-S-H-L-R-R-E-L-K-A-L-L-S-A-E-Q-A-E-L-V-A-H-G-I-A-S-L-I-D-G-I-W-L-R-G-T-L-N-P-Q-G-I-E-A-D-K-A-R-I-I-I-N-D-Y-L-D-K-Q-L-T-F-Y-S-H-K-I"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-D-K-T-L-K-F-T-D-S-H-E-W-V-R-D-N-G-D-G-T-V-T-I-G-I-S-E-H-A-Q-E-M-L-G-D-V-V-F-V-D-L-P-D-V-E-D-E-V-E-A-G-E-S-F-S-L-V-E-S-V-K-A-A-S-D-I-Y-S-P-V-T-G-E-V-V-E-I-N-E-E-L-E-D-S-P-E-L-I-N-E-E-P-Y-E-G-G-W-I-V-K-V-K-L-S-D-P-S-E-L-D-D-L-K-D-A-E-E-Y-L-S-S-I-E-E-E"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-V-L-E-I-L-S-I-P-D-P-R-L-K-V-K-A-E-K-V-T-D-V-S-T-I-Q-T-L-I-D-D-M-L-E-T-L-Y-A-T-G-N-G-I-G-L-A-S-T-Q-V-G-R-K-E-A-V-V-V-I-D-I-S-D-E-R-N-D-P-L-I-L-V-N-P-E-V-V-S-G-E-N-K-A-L-G-Q-E-G-C-L-S-V-P-E-Y-Y-A-D-V-E-R-Y-T-S-V-V-V-S-A-L-D-R-D-G-N-P-I-T-I-E-S-D-E-F-L-A-I-V-M-Q-H-E-I-D-H-L-S-G-N-L-F-I-D-Y-L-S-P-L-K-Q-K-M-A-M-K-K-V-K-K-Y-V-K-A-Q-A-K"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-Q-K-T-T-R-T-M-P-A-H-K-H-V-A-L-V-A-H-D-N-C-K-P-E-L-L-R-W-V-K-E-N-K-E-K-L-Q-R-H-F-L-Y-A-T-G-T-T-G-H-M-L-S-K-E-T-G-L-A-I-K-S-M-I-S-G-P-M-G-G-D-Q-Q-L-G-A-L-I-S-E-G-K-I-D-V-L-V-F-F-W-D-P-L-N-A-V-P-H-D-P-D-V-K-A-L-L-R-I-A-S-V-W-N-I-P-V-A-T-N-R-A-T-A-K-F-L-F-D-S-P-L-L-E-Q-E-V-D-I-E-V-P-D-Y-E-A-Y-L-A-E-R-M"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-I-R-P-L-N-D-K-L-I-V-E-R-Q-E-V-E-N-K-S-E-G-G-I-V-L-T-S-Q-S-V-K-K-S-N-R-G-K-V-I-A-V-G-L-G-K-R-F-E-N-G-E-R-A-A-M-E-V-K-V-G-D-Q-I-I-F-N-D-G-Y-G-V-K-T-E-K-I-D-G-A-E-Y-L-I-L-S-E-S-D-V-L-A-I-V-E"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-I-N-A-T-L-L-G-Q-A-I-S-F-A-L-F-V-W-F-C-M-K-Y-V-W-P-P-L-M-Q-A-I-E-E-R-Q-K-K-I-A-D-G-L-Q-A-A-E-R-A-A-K-D-L-D-L-A-Q-A-N-A-S-D-Q-L-K-E-A-K-R-T-A-T-E-I-I-E-Q-A-N-K-R-K-S-Q-I-I-D-E-A-R-E-E-A-Q-A-E-R-Q-K-I-L-A-Q-A-E-A-E-L-E-A-E-R-N-R-A-R-D-E-L-R-K-Q-V-A-T-L-A-V-A-G-A-E-K-I-L-E-R-T-I-D-K-D-A-Q-K-D-I-L-D-N-I-T-A-K-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-D-L-T-T-I-A-R-P-Y-A-K-A-A-F-D-F-A-V-D-K-G-Q-L-D-Q-W-G-Q-M-L-S-F-A-A-E-V-A-K-N-E-Q-M-N-E-L-L-T-S-S-F-S-A-E-K-M-A-E-I-F-V-A-V-C-G-E-Q-V-D-A-H-G-Q-N-L-L-K-V-M-A-E-N-G-R-L-A-A-L-P-D-V-C-E-Q-F-F-I-L-K-K-E-H-E-K-E-I-D-V-E-V-I-S-A-S-E-L-S-D-E-Q-L-A-N-I-G-S-K-L-E-A-R-L-E-R-K-V-K-L-N-C-S-V-D-E-T-L-L-G-G-V-I-I-R-A-G-D-L-V-I-D-D-S-A-R-G-R-L-N-R-L-S-D-A-L-Q-S"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-P-I-T-F-H-L-D-V-V-S-A-E-K-R-I-F-S-G-R-V-E-T-F-Q-V-T-G-S-E-G-E-L-G-I-F-H-G-H-T-P-L-L-S-A-I-K-P-G-M-V-R-I-V-K-Q-H-G-H-E-E-F-I-Y-V-S-G-G-M-V-E-V-Q-P-G-T-A-T-V-L-A-D-T-A-I-R-G-E-D-L-D-A-A-K-A-E-E-A-K-R-R-A-E-E-K-I-Q-N-Q-H-G-D-M-D-F-A-Q-A-A-S-E-L-A-K-A-I-A-Q-L-R-V-I-E-L-T-K-K-R-R"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-V-L-Q-V-L-T-F-P-D-D-R-L-R-T-V-A-K-P-V-D-A-V-T-P-E-I-Q-K-I-V-D-D-M-I-E-T-M-Y-D-E-E-G-I-G-L-A-A-T-Q-V-D-I-H-K-R-I-V-V-I-D-I-S-E-T-R-D-E-P-M-V-L-I-N-P-E-I-L-E-K-R-G-E-D-G-I-E-E-G-C-L-S-V-P-G-A-R-A-L-V-P-R-A-A-E-V-T-V-K-A-L-D-R-D-G-K-E-F-T-F-E-A-D-D-L-L-A-I-C-V-Q-H-E-L-D-H-L-Q-G-K-L-F-V-D-Y-L-S-P-L-K-R-K-R-I-Q-D-K-L-A-K-I-K-R-F-N-E-K-Q-Q-N-A"} +{"text": "### FUNCTION Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide ### SEQUENCE -M-K-V-G-I-I-M-G-S-K-S-D-W-P-T-M-K-L-A-A-D-M-L-D-Q-F-G-V-S-Y-E-T-K-V-V-S-A-H-R-T-P-Q-L-L-A-D-Y-A-S-S-A-K-E-R-G-I-K-V-I-I-A-G-A-G-G-A-A-H-L-P-G-M-A-A-A-F-T-S-L-P-V-L-G-V-P-V-Q-S-R-A-L-K-G-M-D-S-L-L-S-I-V-Q-M-P-K-G-I-A-V-G-T-L-A-I-G-E-A-G-A-A-N-A-G-I-L-A-A-Q-I-L-G-T-H-D-E-S-I-M-A-K-V-E-A-F-R-N-E-Q-T-E-T-V-L-A-N-P-N-P-A-E-D"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-G-Q-F-S-I-L-G-F-I-A-L-G-G-A-I-G-A-C-S-R-Y-L-V-S-E-F-C-V-L-L-F-G-R-G-F-P-Y-G-T-L-T-V-N-V-V-G-S-F-I-M-G-L-L-I-A-A-F-E-N-E-I-L-A-T-E-P-W-R-Q-V-I-G-L-G-F-L-G-A-L-T-T-F-S-T-F-S-M-D-N-V-L-L-M-Q-Q-G-A-F-F-K-M-G-L-N-I-L-L-N-V-V-L-S-I-S-A-A-W-I-G-F-Q-L-L-M-R-S"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-D-T-E-F-H-Q-L-V-D-A-Q-M-Q-I-I-E-E-S-I-D-D-S-G-A-D-I-D-Y-E-V-S-G-N-V-M-T-L-E-F-E-D-R-S-Q-I-I-I-N-R-Q-E-P-M-H-E-I-W-L-A-S-K-S-G-G-F-H-F-K-L-V-E-D-K-W-T-C-S-K-T-G-M-E-L-F-E-M-V-K-Q-E-C-E-K-H-A-G-E-E-I-D-W-A"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-D-Q-F-Q-H-I-D-V-Q-G-A-Q-A-L-L-E-Q-G-E-A-K-L-V-D-I-R-D-P-Q-S-F-A-V-A-H-A-E-S-A-Y-H-L-T-N-D-T-I-V-A-F-M-E-D-V-E-F-E-Q-P-I-L-V-M-C-Y-H-G-I-S-S-Q-G-A-A-Q-Y-L-V-N-Q-G-F-E-Q-V-Y-S-V-D-G-G-F-E-A-W-Q-R-A-Q-L-P-I-V-R-S"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-N-Q-P-T-S-L-Y-L-A-S-L-L-E-V-E-W-Q-K-P-E-E-F-E-F-P-N-E-F-A-K-H-W-L-E-E-Q-G-S-L-S-R-R-L-K-Q-H-C-Q-E-L-T-V-E-L-L-Q-N-H-I-V-T-A-K-T-L-K-S-D-E-S-Q-L-L-S-E-Q-D-C-L-L-R-E-V-V-L-C-G-D-D-C-P-W-V-V-G-R-T-L-I-P-R-T-T-L-V-D-Q-Q-Y-D-L-A-Q-Q-G-D-I-P-L-G-L-T-V-F-S-A-D-N-V-E-R-D-S-L-Q-M-G-W-V-H-L-P-Q-G-R-F-L-A-R-R-S-R-L-W-M-N-H-K-P-M-L-V-A-E-L-F-L-S-N-S-P-I-Y-A-K-E-R-V"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-S-E-A-P-K-K-R-W-Y-V-V-Q-A-F-S-G-F-E-G-R-V-A-Q-S-L-R-E-H-I-K-M-H-G-M-E-E-L-F-G-E-V-L-V-P-T-E-E-V-V-E-M-R-A-G-Q-R-R-K-S-E-R-K-F-F-P-G-Y-V-L-V-Q-M-I-M-N-D-E-S-W-H-L-V-R-S-V-P-R-V-M-G-F-I-G-G-T-S-D-R-P-A-P-I-T-D-K-E-A-D-A-I-L-N-R-L-E-K-A-S-E-A-P-R-P-R-T-M-Y-E-A-G-E-V-V-R-V-N-E-G-P-F-A-D-F-N-G-T-V-E-E-V-D-Y-E-K-S-R-L-K-V-S-V-S-I-F-G-R-A-T-P-V-E-L-E-F-G-Q-V-E-K-L-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-A-Y-I-K-L-Q-V-A-A-G-A-A-N-P-S-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-F-N-A-K-T-E-S-L-E-K-G-L-P-T-P-V-V-I-T-V-Y-S-D-R-S-F-T-F-V-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-K-S-G-S-G-R-P-N-T-E-K-V-G-T-V-T-D-A-Q-I-Q-E-I-A-E-T-K-A-A-D-M-T-G-A-D-I-E-A-M-K-R-S-I-A-G-T-A-R-S-M-G-L-V-V-E-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-Q-D-K-K-A-I-V-A-E-V-N-E-A-A-S-G-A-L-S-A-V-V-A-D-S-R-G-V-E-V-G-A-M-T-S-L-R-K-Q-A-R-E-A-G-V-Y-M-K-V-V-R-N-T-L-A-R-R-A-V-Q-G-T-D-Y-E-C-L-T-D-T-F-T-G-P-T-L-I-A-F-S-N-E-H-P-G-A-A-A-R-L-F-K-D-F-A-K-E-N-K-D-F-E-I-K-A-A-A-F-E-G-A-L-T-D-A-E-V-L-A-T-L-P-T-Y-D-E-A-I-A-R-L-M-M-C-M-K-E-A-S-A-G-K-L-V-R-T-I-A-A-I-R-D-Q-K-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-I-T-N-E-Q-I-L-D-A-V-A-E-M-S-V-M-Q-V-V-E-L-I-E-A-M-E-E-K-F-G-V-S-A-A-A-A-V-V-A-G-G-A-A-A-G-A-A-V-E-E-Q-T-E-F-D-V-I-L-E-S-A-G-G-N-K-V-A-V-I-K-A-V-R-G-A-T-G-L-G-L-K-E-A-K-A-L-V-D-G-A-P-A-P-L-K-E-G-V-D-K-A-E-A-D-A-L-K-A-Q-L-E-E-A-G-A-T-V-A-V-K"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-E-R-K-E-V-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-E-K-S-T-R-G-V-V-L-A-V-G-K-G-R-I-L-E-N-G-T-V-L-P-L-D-V-K-V-G-D-T-V-I-F-A-E-G-Y-G-T-K-T-E-K-I-D-G-K-E-V-L-V-M-S-E-N-D-I-M-A-I-V-E"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-T-V-S-T-N-E-F-K-G-G-L-K-L-M-L-D-N-E-P-C-V-I-L-E-N-E-Y-V-K-P-G-K-G-Q-A-F-N-R-V-K-I-R-K-L-L-S-G-K-V-L-E-K-T-F-K-S-G-D-T-C-E-V-A-D-V-M-D-I-D-L-D-Y-L-Y-S-D-G-E-F-Y-H-F-M-N-N-E-T-F-E-Q-I-A-A-D-A-K-A-V-G-E-N-A-K-W-L-V-E-N-N-T-C-M-I-T-L-W-N-G-N-P-I-T-V-T-P-P-N-F-V-E-L-E-V-T-D-T-D-P-G-L-K-G-D-T-Q-G-T-G-G-K-P-A-T-L-A-T-G-A-V-V-R-V-P-L-F-I-A-I-G-E-V-I-K-V-D-T-R-T-G-E-Y-V-G-R-V-K"} +{"text": "### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-K-P-N-Y-S-V-N-T-S-P-K-R-S-D-E-P-I-W-W-G-L-F-G-A-G-G-T-W-F-A-M-L-T-P-I-T-V-L-V-L-G-I-L-V-P-L-G-V-I-D-A-E-A-M-S-Y-E-R-V-S-A-F-A-T-S-I-I-G-A-L-F-I-I-G-T-L-A-L-P-M-W-H-A-M-H-R-V-H-H-G-M-H-D-L-K-F-H-T-G-V-I-G-K-V-A-C-Y-A-F-A-G-L-I-T-A-L-A-V-I-F-I-F-M-I"} +{"text": "### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-S-N-R-K-P-Y-V-R-E-V-K-R-T-W-W-K-N-H-P-F-Y-R-F-Y-M-L-R-E-A-T-V-L-P-L-I-L-F-T-L-F-L-T-F-G-L-G-C-L-V-K-G-P-E-A-W-Q-G-W-L-A-F-M-A-N-P-I-V-V-A-I-N-I-V-A-L-L-G-S-L-F-H-A-Q-T-F-F-S-M-M-P-Q-V-M-P-I-R-L-K-G-K-P-V-D-K-K-I-I-V-L-T-Q-W-A-A-V-A-F-I-S-L-I-V-L-I-V-V"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-A-E-A-A-P-Q-E-A-Q-Q-N-F-A-I-Q-R-I-F-L-K-D-V-S-F-E-A-P-N-S-P-V-I-F-Q-K-E-W-N-P-D-V-K-L-D-L-D-T-Q-S-R-E-L-G-E-G-V-Y-E-V-V-L-R-L-T-V-T-V-K-N-E-E-E-T-A-F-L-C-E-V-Q-Q-G-G-I-F-T-A-E-Q-M-E-A-G-Q-L-A-H-C-L-G-A-F-C-P-N-I-L-F-P-Y-A-R-E-T-I-S-S-L-V-V-K-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-M-N-Y-L-Q-Q-Q-A-Q-Q-G-E-A-Q-A"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-S-F-S-D-Q-N-L-I-W-V-D-L-E-M-T-G-L-D-P-E-T-H-K-I-I-E-I-A-S-I-V-T-D-S-E-L-N-I-L-A-E-G-P-V-L-A-V-H-Q-P-E-E-E-L-A-K-M-D-D-W-C-T-N-T-H-T-A-S-G-L-V-E-R-V-R-N-S-K-I-S-E-Q-D-A-V-A-Q-T-I-E-F-L-E-K-W-V-P-K-G-V-S-P-I-C-G-N-S-I-G-Q-D-R-R-F-L-Y-K-H-M-P-E-L-E-E-Y-F-H-Y-R-Y-L-D-V-S-T-L-K-E-L-T-R-R-W-K-P-E-V-L-D-G-F-S-K-Q-G-T-H-L-A-L-D-D-I-R-E-S-I-A-E-L-K-Y-Y-R-E-T-I-F-K-I"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-I-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-N-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-P-V-S-H-H-S-G-D-R-P-Q-G-D-R-P-Q-E-K-S-E-D"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-G-G-L-T-Y-T-L-V-V-N-G-S-V-Y-G-S-Q-S-A-R-S-A-Y-Q-F-A-Q-A-V-I-E-Q-G-H-T-L-V-S-V-F-F-Y-Q-D-G-V-T-N-G-T-A-L-S-V-P-A-N-D-E-F-D-L-T-K-A-W-Q-G-L-A-K-E-H-D-V-R-L-E-T-C-V-A-A-A-L-R-R-G-I-I-S-E-D-E-A-T-Q-H-G-L-T-Q-N-N-L-A-E-G-F-V-Q-A-G-L-G-S-L-A-E-A-M-L-T-Q-D-R-V-V-Q-F"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-N-Q-L-V-R-K-P-R-A-K-Q-V-V-K-S-N-V-P-A-L-E-A-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-T-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-A-L-D-C-A-G-V-N-D-R-K-Q-G-R-S-K-Y-G-V-K-R-P-K-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-I-G-Q-R-K-I-L-P-D-P-K-F-K-S-E-L-L-A-K-F-V-N-I-L-M-V-D-G-K-K-S-T-A-E-K-I-V-Y-T-A-L-D-S-M-A-E-K-S-G-K-D-H-L-A-I-F-E-E-A-L-E-N-V-R-P-A-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-P-V-R-R-N-A-L-A-M-R-W-L-V-E-A-A-R-K-R-G-E-K-S-M-A-Q-R-L-A-A-E-M-L-D-A-S-E-N-K-G-T-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION This regulatory protein, when combined with SAM represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-A-D-W-N-G-E-Y-I-S-P-Y-A-E-H-G-K-K-S-E-Q-V-K-K-I-T-V-S-I-P-L-K-V-L-K-V-L-T-D-E-R-T-R-R-Q-I-N-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-Y-T-G-Q-P-L-P-T-D-E-D-L-R-K-D-R-P-D-D-I-P-T-E-A-K-A-L-M-T-A-M-G-I-E-F-E-A-F-D-E-E"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-A-G-M-I-E-R-Y-T-G-S-I-T-E-A-G-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-V-L-M-N-V-E-A-D-Q-A-V-I-D-E-L-E-T-A-F-R-F-N-D-A-V-L-R-N-M-I-M-R-T-K-A-A-I-T-E-Q-S-I-M-L-K-Q-K-E-E-R-A-P-R-R-E-E-R-S-E-A-K-P-E-A-K-S-E-A-A-E"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-T-N-R-M-E-L-S-G-T-I-A-K-P-P-I-R-S-K-S-P-G-G-I-E-H-C-R-F-W-L-E-H-R-S-T-V-I-E-A-D-L-P-R-Q-V-Y-C-R-M-P-V-V-V-S-G-L-R-S-Q-A-I-T-Q-N-L-V-Q-G-S-N-I-K-V-S-G-F-V-A-Y-Q-T-G-R-N-G-V-G-K-L-V-L-H-A-D-N-I-T-Q-I"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-D-K-I-G-N-L-G-G-L-G-D-T-V-N-V-K-S-G-Y-A-R-N-F-L-I-P-Q-G-K-A-V-M-A-T-K-G-N-V-E-M-F-E-A-R-R-A-E-L-E-A-K-V-A-E-Q-L-A-A-A-E-A-R-A-E-K-V-N-A-L-E-A-V-V-I-A-S-K-A-G-D-E-G-K-L-F-G-S-I-G-T-R-D-I-A-E-A-I-T-A-A-G-V-E-V-A-K-S-E-V-R-L-P-E-G-A-L-R-T-T-G-E-F-E-I-S-V-Q-L-H-S-E-V-F-A-T-A-K-V-Q-V-V-A-A-E"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-S-R-G-I-N-K-V-I-L-V-G-N-L-G-N-D-P-E-I-R-Y-M-P-N-G-G-A-V-A-N-I-T-I-A-T-S-E-S-W-R-D-K-A-T-G-E-Q-R-E-K-T-E-W-H-R-V-V-L-F-G-K-L-A-E-V-A-G-E-Y-L-R-K-G-S-Q-V-Y-V-E-G-Q-L-Q-T-R-K-W-Q-D-Q-S-G-Q-D-R-Y-S-T-E-V-V-V-Q-G-F-N-G-V-M-Q-M-L-G-G-R-A-Q-G-G-A-P-A-M-G-G-Q-Q-Q-Q-Q-G-G-W-G-Q-P-Q-Q-P-A-Q-Q-Q-Y-N-A-P-Q-Q-Q-Q-Q-A-P-Q-Q-P-Q-Q-Q-Y-N-E-P-P-M-D-F-D-D-D-I-P-F"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-A-K-E-T-Q-L-Q-V-E-A-I-K-N-G-T-V-I-D-H-I-P-A-Q-I-G-I-K-V-L-K-L-F-D-M-H-N-S-S-Q-R-V-T-I-G-L-N-L-P-S-S-A-L-G-H-K-D-L-L-K-I-E-N-V-F-I-N-E-E-Q-A-S-K-L-A-L-Y-A-P-H-A-T-V-N-Q-I-E-N-Y-E-V-V-K-K-L-A-L-E-L-P-E-K-I-N-N-V-F-E-C-P-N-S-N-C-I-S-H-N-E-P-V-E-S-S-F-K-V-F-E-K-K-E-E-I-R-L-K-C-K-Y-C-E-K-V-F-S-R-E-I-V-T-E-R"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-R-T-I-M-A-F-D-F-G-T-K-S-I-G-S-A-I-G-Q-E-I-T-G-T-A-S-P-L-K-A-F-K-A-N-D-G-I-P-N-W-D-D-I-E-K-Q-I-K-E-W-Q-P-D-L-L-V-V-G-L-P-T-D-L-H-G-K-D-L-E-T-I-T-P-R-A-K-K-F-A-K-R-L-Q-G-R-Y-G-L-P-V-E-L-H-D-E-R-L-S-T-S-E-A-R-A-E-L-F-S-M-G-G-Y-K-A-L-S-K-G-N-I-D-C-Q-S-A-V-V-I-L-E-S-W-F-E-A-L-W-G-E"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-L-G-L-G-T-D-I-A-E-I-E-R-I-E-K-A-L-G-R-S-G-E-P-F-A-Q-R-I-L-S-E-D-E-M-A-K-F-S-Q-L-K-Q-Q-G-R-Y-L-A-K-R-F-A-A-K-E-A-A-S-K-A-L-G-T-G-I-A-Q-G-V-T-F-H-D-F-T-V-S-N-D-E-L-G-K-P-V-L-M-L-S-G-V-A-Q-K-M-A-Q-T-M-G-V-N-H-V-H-L-S-I-S-D-E-R-H-Y-A-V-A-T-V-I-L-E-S"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-I-F-V-I-A-L-T-L-L-F-G-W-L-Q-Y-T-L-W-F-G-K-N-G-V-S-D-Y-Y-T-V-K-D-E-I-E-V-Q-Q-Q-V-N-S-K-L-Q-A-R-N-N-E-M-F-A-E-I-D-D-L-K-Q-G-L-D-A-I-E-E-R-A-R-H-E-L-G-L-V-K-E-G-E-T-F-Y-R-I-V-G-E-E-N-P"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-Y-Q-K-R-Q-A-P-T-L-S-S-K-E-A-A-I-Q-L-L-S-R-R-D-H-G-L-Y-E-L-H-Q-K-L-A-M-K-G-Y-E-E-A-D-I-E-A-A-I-N-F-C-L-E-H-N-Y-L-D-D-L-R-Y-A-K-S-Q-V-R-Q-H-V-Y-K-G-H-G-E-R-R-I-R-Q-E-L-N-Q-K-R-V-A-E-S-V-I-E-Q-A-M-A-E-E-P-Q-D-W-F-E-L-A-K-L-A-A-E-K-K-F-K-G-I-K-A-K-D-Q-K-E-Y-A-K-Q-V-R-F-L-Q-Y-R-G-Y-S-F-D-Q-I-S-Y-A-L-S-F-E-D-E-D"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-M-I-G-D-E-V-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-V-N-A-P-K-E-V-S-V-H-R-E-E-I-Y-M-R-I-Q-A-E-K-G-N-G-N-V-A-S-G-N-Y"} +{"text": "### FUNCTION Catalyzes the decarboxylation of oxaloacetate coupled to Na translocation ### SEQUENCE -M-T-N-I-G-S-L-L-V-D-A-A-T-L-M-V-T-G-M-A-V-V-F-I-F-L-T-I-L-V-Y-L-V-R-L-L-S-K-L-V-P-E-E-V-P-E-P-I-A-A-P-K-T-N-T-R-V-Q-S-T-S-S-A-V-S-P-Q-V-V-A-A-I-S-A-A-I-H-Q-H-R-A-S-I-A-K"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-T-V-D-H-T-R-M-N-A-P-A-V-R-V-A-K-T-M-Q-T-P-K-G-D-T-I-T-V-F-D-L-R-F-T-A-P-N-K-D-I-L-S-E-K-G-I-H-T-L-E-H-L-Y-A-G-F-M-R-N-H-L-N-G-D-S-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-T-P-S-E-Q-Q-V-A-D-A-W-L-A-S-M-E-D-V-L-K-V-E-S-Q-N-K-I-P-E-L-N-E-Y-Q-C-G-T-A-A-M-H-S-L-E-E-A-Q-Q-I-A-K-N-I-L-A-A-G-V-S-V-N-K-N-D-E-L-A-L-P-E-S-M-L-K-E-L-R-V-D"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-M-K-G-K-E-T-M-S-N-E-K-I-V-V-G-K-F-G-A-T-Y-G-I-R-G-W-L-K-V-F-S-Y-T-D-N-A-E-S-I-F-D-Y-S-P-W-Y-I-N-Q-K-G-K-W-V-E-Y-K-V-E-S-W-K-R-H-N-K-G-M-V-A-K-L-E-G-M-D-V-R-E-D-A-H-L-M-T-N-F-E-I-A-I-D-P-A-V-L-P-E-L-S-E-D-E-F-Y-W-R-E-L-F-G-M-H-V-V-T-T-K-G-Y-D-L-G-V-V-T-D-M-L-E-T-G-S-N-D-V-L-V-V-K-A-N-L-K-D-A-F-G-Q-K-E-R-L-I-P-F-L-E-E-Q-V-I-I-K-V-D-R-E-A-Q-R-I-E-V-D-W-D-P-G-F"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-N-I-I-K-A-L-E-E-E-Q-M-K-S-G-L-P-K-F-A-P-G-D-T-V-V-V-Q-V-K-V-K-E-G-D-R-E-R-L-Q-A-F-E-G-V-V-I-A-I-R-N-R-G-L-H-S-A-F-T-V-R-K-I-S-N-G-E-G-V-E-R-T-F-Q-T-H-S-P-I-V-D-S-I-E-V-K-R-R-G-A-V-R-R-A-K-L-Y-Y-L-R-E-R-S-G-K-S-A-R-I-K-E-K-L-A-K-K"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-S-K-I-T-I-V-Q-C-P-Q-C-G-T-D-V-E-W-G-E-Q-S-P-H-R-P-F-C-S-K-K-C-Q-M-I-D-F-G-E-W-A-D-E-E-N-A-I-A-G-A-P-D-M-S-D-S-D-G-W-S-E-D-Q-Y"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-E-V-N-V-P-L-S-F-S-D-A-A-A-S-R-V-K-A-L-I-A-E-E-E-N-P-A-L-K-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-N-V-N-D-G-D-T-T-I-E-N-S-G-V-T-L-V-V-D-P-M-S-L-Q-Y-L-I-G-G-I-V-D-Y-T-E-G-L-E-G-A-R-F-F-V-N-N-P-N-A-T-T-T-C-G-C-G-A-S-F-S-V"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-E-K-V-P-M-T-L-R-G-E-Q-M-L-R-T-E-L-E-R-L-L-K-L-R-P-Q-I-S-E-A-I-A-E-A-R-E-L-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-E-Q-G-I-C-E-A-Q-I-R-D-I-E-Y-K-L-S-V-A-Q-V-I-D-V-T-K-M-E-N-T-G-K-V-I-F-G-S-T-V-T-L-I-D-V-D-T-D-E-E-K-T-Y-Q-I-V-G-D-D-E-A-D-I-K-A-G-R-I-S-V-S-S-P-I-A-R-G-L-I-G-K-M-E-G-D-E-V-A-I-Q-T-P-G-G-A-K-D-F-E-I-D-R-V-E-Y-I"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-G-L-E-R-Q-L-T-E-M-L-E-A-P-V-E-A-S-G-Y-E-L-V-G-L-E-F-I-R-A-G-A-H-S-T-L-R-I-Y-I-D-H-E-N-G-I-N-V-D-D-C-A-E-V-S-H-Q-V-S-A-V-L-D-V-E-D-P-I-S-V-A-Y-S-L-E-V-S-S-P-G-L-E-R-P-L-F-K-A-A-H-Y-E-Q-F-I-G-H-E-V-S-I-V-L-K-M-A-V-A-N-R-R-K-W-K-G-I-I-H-G-V-D-G-E-T-V-T-V-T-V-E-G-Q-Q-E-E-F-A-L-S-N-I-S-K-A-N-L-I-P-K-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-K-E-F-S-R-T-Q-R-V-A-Q-Q-L-Q-K-E-L-A-M-I-L-Q-R-E-V-R-D-S-R-L-G-M-V-T-I-S-D-V-E-V-S-R-D-L-A-Y-A-K-V-F-V-T-F-L-C-V-G-E-Q-T-P-E-S-C-L-A-A-L-R-E-H-E-V-H-I-R-M-M-L-G-K-R-I-R-L-R-L-T-P-E-I-R-F-Y-Y-D-N-T-L-V-E-G-M-R-M-S-N-L-V-T-E-V-V-N-S-D-K-Q-K-Q-K-N-S-G-R-E-D-E-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-N-A-E-T-K-A-A-I-V-A-E-Y-A-Q-S-E-G-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-S-I-N-H-L-Q-G-H-F-K-A-H-K-G-D-H-H-S-R-R-G-L-L-R-M-V-S-R-R-R-K-L-L-D-Y-L-K-G-K-D-L-A-R-Y-Q-D-L-I-K-R-L-G-L-R-R"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-T-E-T-I-S-L-I-K-S-S-I-K-S-I-Q-D-Y-P-K-P-G-I-L-F-R-D-V-T-S-L-L-E-D-A-K-A-Y-Q-A-T-I-G-L-L-V-E-R-Y-K-D-M-G-F-T-K-V-V-G-T-E-A-R-G-F-L-F-G-A-P-L-A-L-E-L-G-V-G-F-V-P-V-R-K-P-G-K-L-P-R-P-T-I-A-Q-S-Y-E-L-E-Y-G-I-D-T-L-E-I-H-T-D-A-I-V-E-G-D-K-V-L-V-V-D-D-L-L-A-T-G-G-T-I-E-A-T-T-K-L-I-R-Q-L-G-G-E-V-E-H-A-A-F-V-I-N-L-P-E-I-G-G-D-K-R-L-E-A-L-G-L-N-V-F-S-I-C-D-F-E-G-H"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-G-G-M-G-N-L-M-K-Q-A-Q-Q-M-Q-E-R-M-Q-K-L-Q-E-E-I-A-N-M-E-V-T-G-E-S-G-A-G-L-V-K-V-T-I-T-G-S-H-S-V-R-R-V-D-I-D-E-S-L-M-E-D-D-K-E-M-L-E-D-L-I-A-A-A-F-N-D-A-A-R-R-V-E-E-T-Q-K-E-K-M-A-S-V-T-G-G-M-Q-L-P-P-G-M-K-M-P-F"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-R-T-S-H-M-L-E-Q-L-M-E-A-L-R-C-L-P-G-V-G-P-K-S-A-Q-R-M-A-F-H-L-L-Q-R-D-R-K-G-G-L-Q-L-A-D-A-L-S-Q-S-M-T-E-I-G-H-C-A-E-C-R-T-F-T-E-E-E-V-C-H-I-C-T-N-P-K-R-Q-E-N-G-Q-I-C-V-V-E-S-P-A-D-I-A-A-V-E-A-T-G-Q-Y-S-G-R-Y-F-V-L-M-G-H-L-S-P-L-D-G-I-G-P-S-D-I-G-L-D-V-L-D-Y-R-L-R-R-G-D-I-S-E-V-I-L-A-T-N-P-T-V-E-G-E-A-T-A-H-Y-I-A-E-L-C-R-E-H-Q-V-E-A-S-R-I-A-H-G-V-P-V-G-G-E-L-E-L-V-D-G-T-T-L-S-H-S-L-L-G-R-H-K-I"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-T-E-Y-V-L-L-L-V-G-T-V-L-V-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-L-E-T-A-I-G-M-G-L-A-T-T-F-V-L-T-L-A-S-V-C-A-Y-L-V-E-S-Y-I-L-R-P-L-G-I-E-Y-L-R-T-M-S-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-V-V-H-K-T-S-P-T-L-Y-R-L-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-I-N-E-N-H-N-F-I-E-S-I-I-Y-G-F-G-A-A-V-G-F-S-L-V-L-I-L-F-A-S-M-R-E-R-I-A-A-A-D-V-P-V-P-F-K-G-A-S-I-A-M-I-T-A-G-L-M-S-L-A-F-M-G-F-T-G-L-V-K"} +{"text": "### FUNCTION Phosphorelay protein which receives a sensory signal from a sensor kinase and transmit it to LuxO At low cell density, a phosphoryl group is transferred from the sensor kinase, probably on His-56 and this phosphoryl group is further transferred to LuxO ### SEQUENCE -M-T-I-L-N-Q-Q-K-I-D-E-L-S-I-E-I-G-S-D-N-V-P-V-L-L-D-I-F-L-G-E-M-D-T-Y-I-D-N-L-S-Q-L-E-G-S-E-R-L-M-Y-L-K-E-I-S-H-A-L-K-S-S-A-A-S-F-G-A-D-S-L-C-E-L-A-M-S-I-D-K-K-A-K-S-G-E-L-V-E-Q-G-S-E-V-N-T-M-L-D-R-L-N-E-T-R-D-A-Y-R-S-W-T-Q"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-T-I-F-S-S-L-N-Q-F-S-K-G-H-V-S-W-L-L-L-L-L-F-I-I-F-F-E-A-C-A-L-Y-F-Q-H-V-M-M-L-A-P-C-V-M-C-I-Y-E-R-V-A-M-M-G-I-G-G-A-A-I-I-G-L-I-A-P-N-N-A-L-F-R-W-L-G-L-I-G-W-G-L-S-S-Y-K-G-L-M-L-A-M-Q-H-V-D-Y-Q-F-N-P-S-P-F-A-T-C-D-L-F-V-T-F-P-S-W-A-P-L-N-Q-W-V-P-W-M-F-E-A-Y-G-D-C-S-K-I-V-W-Q-F-F-D-L-S-M-P-Q-W-L-V-V-I-F-A-G-N-L-V-A-L-A-L-I-V-I-A-Q-F-F-P-V-K-R-K-N-P-I-R"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-K-N-Y-Q-L-V-L-A-S-T-S-P-F-R-Q-Q-L-L-E-K-L-S-V-P-F-I-C-L-S-P-D-C-D-E-T-P-Y-E-S-E-A-P-L-D-L-V-Q-R-L-A-V-N-K-A-T-S-C-S-I-K-K-P-S-L-V-I-G-S-D-Q-V-C-V-I-D-G-K-I-V-G-K-P-L-N-R-E-N-A-I-N-Q-L-L-A-Q-S-G-K-A-I-T-F-Y-T-G-L-A-V-Y-N-S-V-T-N-L-T-E-V-G-Y-D-T-F-E-V-H-F-R-N-L-N-R-E-Q-I-E-R-Y-V-D-R-E-E-P-F-Y-C-A-G-S-F-K-S-E-G-M-G-I-C-L-F-E-K-L-V-G-K-D-P-N-T-L-V-G-L-P-L-I-D-L-I-D-M-L-Q-K-Q-G-F-E-I-L"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-R-L-C-A-E-Q-T-H-L-S-A-K-E-V-E-D-A-V-K-D-I-L-E-H-M-A-S-T-L-E-S-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-E-P-R-V-G-R-N-P-K-T-G-D-K-V-E-L-E-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-E-R-V-N-L-G"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-Q-I-L-D-F-I-P-L-I-I-F-F-A-L-Y-K-M-Y-D-I-Y-V-A-T-G-A-L-I-V-A-T-A-V-Q-L-I-V-T-Y-A-L-Y-K-K-V-E-K-M-Q-L-I-T-F-V-I-V-T-I-F-G-S-M-T-I-F-F-H-D-D-N-F-I-K-W-K-V-T-I-I-Y-V-V-L-A-V-G-L-T-A-S-H-L-M-G-K-S-V-V-K-G-M-L-G-K-E-I-T-L-P-D-A-I-W-A-K-I-N-W-A-W-V-G-F-F-S-F-F-A-G-L-N-I-Y-I-A-Y-E-L-P-L-D-V-W-V-N-F-K-V-F-G-M-L-I-A-T-F-A-Y-M-I-A-T-G-V-Y-I-Y-K-H-M-P-K-E-E-K-N-N-S-S-D-V-S-V-D-D"} +{"text": "### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate with acetyl coenzyme A ### SEQUENCE -M-Y-F-K-M-I-T-S-A-P-W-V-L-Y-P-E-I-G-E-D-P-S-K-K-W-I-F-R-E-P-K-I-S-D-G-D-G-I-Y-S-L-I-A-D-C-P-P-L-D-M-N-S-S-Y-C-N-F-L-Q-S-T-H-F-S-K-T-S-I-L-V-E-H-K-G-D-I-A-G-F-I-S-G-Y-Q-K-P-D-E-Q-D-V-L-F-I-W-Q-V-A-V-S-P-R-F-R-G-N-G-L-A-F-R-M-L-K-E-L-L-E-R-E-A-L-S-E-V-K-S-V-E-T-T-I-T-E-D-N-Q-A-S-W-A-L-F-K-K-L-D-A-M-N-G-N-H-G-Q-V-S-T-F-L-D-E-K-A-H-F-K-G-K-H-D-T-E-F-L-Y-R-I-P-L-K"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-R-T-L-D-E-C-R-N-S-E-R-R-V-V-A-D-N-W-E-S-V-R-M-L-L-K-D-D-N-M-G-F-S-F-H-I-T-T-I-Y-E-G-T-E-T-H-I-H-Y-Q-N-H-L-E-S-V-F-C-M-S-G-E-G-E-I-E-V-V-G-G-E-T-Y-P-I-K-P-G-T-L-Y-I-L-D-K-H-D-E-H-Y-L-R-A-Y-K-N-K-E-M-V-M-A-C-V-F-N-P-P-I-T-G-A-E-V-H-D-E-N-G-V-Y-P-L-V-D"} +{"text": "### FUNCTION Required for spatial organization of the terminus region of the chromosome during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-Q-L-E-N-L-E-C-G-W-K-W-K-Y-L-I-K-K-W-K-D-G-E-A-I-T-R-H-I-D-T-S-E-A-D-A-A-I-A-E-L-R-R-I-E-H-E-P-T-L-V-L-A-W-I-E-K-H-M-S-E-E-L-E-N-K-L-K-Q-A-I-R-A-K-R-K-R-H-F-N-A-E-Q-V-H-T-K-K-K-S-I-D-L-D-Y-R-V-W-E-K-L-S-N-R-A-N-E-L-G-C-T-L-S-D-A-I-E-Y-L-L-S-E-A-S-R-S-E-K-A-S-Q-K-V-T-S-I-K-E-D-L-S-K-L-L-S-S"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-E-L-A-E-N-L-F-D-K-L-G-F-S-K-R-D-A-K-E-T-V-E-V-F-F-E-E-I-R-K-A-L-E-S-G-E-Q-V-K-L-S-G-F-G-N-F-D-L-R-D-K-N-E-R-P-G-R-N-P-K-T-G-E-D-I-P-I-T-A-R-R-V-V-T-F-R-P-G-Q-K-L-K-A-R-V-E-N-L-K-K-E-Q"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-K-F-E-A-V-V-R-T-E-L-G-K-G-A-S-R-R-L-R-H-A-G-K-F-P-A-V-V-Y-G-G-E-E-A-A-V-A-I-V-L-N-H-D-D-I-V-N-Q-M-D-K-P-E-F-Y-E-G-I-V-L-V-I-D-G-K-E-V-K-V-K-P-Q-D-V-Q-R-H-A-F-K-P-K-V-E-H-M-D-F-I-R-I"} +{"text": "### FUNCTION Mediates the efflux of short-chain diamines when energized by an electrochemical gradient ### SEQUENCE -M-T-R-N-E-R-I-F-H-A-V-L-F-E-L-M-A-L-A-I-I-V-P-A-A-A-L-I-T-G-K-G-S-S-D-L-A-L-V-G-I-G-L-S-L-Y-T-V-V-W-N-Y-I-Y-N-L-Y-F-D-K-W-F-G-S-N-R-A-D-R-S-L-A-M-R-L-G-H-T-V-G-F-E-G-G-L-I-F-I-S-I-P-V-I-A-W-F-L-E-I-T-F-L-R-A-L-M-L-E-A-G-F-L-V-F-F-L-F-Y-A-T-G-F-N-W-L-Y-D-K-V-Q-P-F-G-K-M-R-K-L-L-V"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-K-N-F-E-W-V-T-P-D-S-D-L-L-E-R-E-S-T-K-V-Q-P-P-K-L-Y-N-V-V-L-N-N-D-D-Y-T-P-M-D-F-V-I-E-V-L-E-R-F-F-S-H-D-I-D-K-A-T-Q-I-M-L-K-V-H-Y-E-G-K-A-V-C-G-T-Y-S-A-E-I-A-E-T-K-V-A-Q-V-T-M-Y-A-R-E-N-E-H-P-L-L-C-T-M-E-Q-A"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-P-I-M-D-A-L-V-P-M-V-V-E-Q-T-S-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-E-R-V-I-F-L-T-G-Q-V-E-D-H-M-A-N-L-V-V-A-Q-L-L-F-L-E-S-E-N-P-D-K-D-I-F-L-Y-I-N-S-P-G-G-S-V-T-A-G-M-S-I-Y-D-T-M-Q-F-I-K-P-N-V-S-T-V-C-M-G-Q-A-C-S-M-G-A-F-L-L-A-G-G-A-A-G-K-R-Y-V-L-P-N-S-R-V-M-I-H-Q-P-L-G-G-F-Q-G-Q-A-S-D-I-Q-I-H-A-Q-E-I-L-T-I-K-Q-K-L-N-N-L-L-A-E-H-T-G-Q-P-L-E-V-I-E-R-D-T-D-R-D-N-F-M-S-A-E-Q-A-V-E-Y-G-I-V-D-A-V-L-S-H-R-G-A"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-L-E-F-F-R-P-Q-K-K-T-S-A-S-L-A-K-E-R-L-Q-I-I-V-A-E-R-R-S-Q-N-D-P-A-P-S-Y-L-P-Q-L-K-E-D-I-L-K-V-I-S-K-Y-V-D-I-D-P-N-M-V-D-L-T-F-E-H-K-D-D-D-I-S-V-L-E-L-N-V-K-L-P-D-D-E-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-Q-P-I-K-L-L-V-G-L-A-N-P-G-P-E-Y-A-K-T-R-H-N-A-G-A-W-V-V-E-E-L-A-R-V-H-N-V-T-L-K-N-E-P-K-F-F-G-L-T-G-R-I-M-V-N-G-Q-D-L-R-L-L-I-P-T-T-F-M-N-L-S-G-K-A-I-A-A-L-A-K-F-Y-Q-I-K-P-E-E-I-M-V-A-H-D-E-L-D-L-P-P-G-V-A-K-F-K-K-G-G-G-H-G-G-H-N-G-L-R-D-T-I-S-K-L-G-N-N-K-D-F-Y-R-L-R-I-G-I-G-H-P-G-H-K-D-K-V-A-G-F-V-L-G-K-A-P-A-K-E-Q-E-L-L-D-A-A-A-D-E-A-V-R-S-L-D-I-L-I-K-D-G-L-S-K-A-Q-N-R-L-H-T-F-K-A-E"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-I-E-L-D-L-Q-L-A-V-E-N-E-E-G-L-P-S-Q-Q-D-F-Q-L-W-L-D-K-T-I-P-L-F-Q-P-Q-A-E-V-T-I-R-I-V-D-E-K-E-S-H-A-L-N-H-E-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-A-P-P-G-M-E-I-D-L-L-G-D-L-I-I-C-R-Q-V-V-E-K-E-A-I-E-Q-N-K-P-L-L-A-H-W-A-H-M-V-V-H-G-S-L-H-L-L-G-Y-D-H-I-E-D-D-E-A-E-E-M-E-S-L-E-T-E-I-M-Q-G-M-G-Y-E-D-P-Y-I-A-E-K-E"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-Q-L-I-A-V-G-T-K-M-P-K-W-V-E-E-G-F-Q-E-Y-R-R-R-F-P-H-D-M-P-L-E-L-V-E-I-S-A-G-K-R-G-K-N-A-D-I-A-R-I-L-Q-K-E-G-E-A-M-L-A-A-V-P-K-G-N-R-I-V-T-L-D-I-P-G-K-K-W-D-T-P-Q-L-A-E-Q-L-E-A-W-K-L-D-G-R-D-V-S-I-L-I-G-G-P-E-G-L-A-P-A-C-K-A-A-A-D-Q-S-W-S-L-S-A-L-T-L-P-H-P-L-V-R-I-V-M-A-E-S-L-Y-R-A-W-S-I-T-A-N-H-P-Y-H-R-E"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-V-K-K-P-E-N-M-T-F-E-A-T-I-E-E-L-D-S-L-V-D-Q-L-E-N-G-D-L-A-L-D-D-A-L-R-K-F-E-R-G-I-A-L-A-R-A-G-Q-T-K-L-S-D-A-E-Q-R-V-S-I-L-L-S-E-D-D-E-A-P-L-N-D-F-K-P-D-S-E"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-G-A-S-V-K-P-A-A-R-R-N-A-R-Q-F-A-L-Q-A-I-Y-S-W-Q-I-T-K-E-N-V-A-T-I-E-E-Q-F-L-S-G-D-K-Y-D-E-E-E-L-R-A-S-E-P-A-L-A-A-P-E-T-D-V-A-Y-F-R-E-L-L-S-G-V-V-L-S-H-A-E-L-D-S-K-I-R-P-Y-V-S-R-P-M-Q-D-L-D-M-M-E-L-A-L-L-R-L-A-M-Y-E-M-T-R-R-E-D-V-P-Y-K-V-V-I-N-E-A-I-E-L-A-K-V-F-A-A-E-D-S-H-K-F-V-N-G-V-L-D-K-A-A-P-H-V-R-K-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-S-E-N-D-T-K-V-I-D-S-R-L-V-A-D-G-H-Q-V-R-R-R-R-Q-C-L-A-C-S-E-R-F-T-T-F-E-T-A-E-L-V-M-P-K-V-I-K-S-N-G-N-R-E-P-F-D-E-D-K-M-V-G-G-I-Q-R-A-L-E-K-R-P-V-S-A-D-S-I-E-L-A-I-S-M-I-K-S-Q-L-R-A-T-G-E-R-E-V-P-S-Q-M-I-G-N-L-V-M-D-Q-L-K-E-L-D-K-V-A-Y-I-R-F-A-S-V-Y-R-S-F-E-D-I-R-E-F-G-E-E-I-A-R-L-E-D"} +{"text": "### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-S-E-T-T-Q-G-P-T-H-F-R-L-M-S-K-L-K-A-I-G-P-Y-L-R-E-P-Q-S-Q-E-G-R-Y-Y-F-D-C-L-S-V-C-V-D-D-K-K-S-P-E-K-R-E-F-W-G-W-W-M-D-L-E-S-I-E-G-G-F-T-A-K-Y-H-I-G-K-Y-N-K-E-G-K-W-V-S-E-A-L-P-Q-K-V-V-E-E-V-Y-F-T-Q-S-T-F-H-Q-K-L-I-D-T-L-A-E-H-F-K-L-E-V-E-Y-H-T-E-S-F-D-F-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-N-E-E-N-K-V-T-E-E-E-L-D-Q-I-I-E-E-A-E-K-V-E-A-A-A-Q-E-A-E-A-E-L-E-E-I-G-D-E-K-D-A-K-I-A-Q-L-E-A-A-L-L-S-S-E-T-K-V-K-D-Q-Q-D-A-V-L-R-A-K-A-E-V-E-N-M-R-R-R-T-E-Q-E-I-D-K-A-R-K-Y-A-L-N-K-F-A-E-E-L-L-P-V-I-D-N-L-E-R-A-I-Q-A-A-D-T-E-N-E-V-I-K-P-I-L-E-G-V-E-L-T-H-K-T-F-V-D-V-V-A-K-F-G-L-K-E-I-N-P-E-G-E-T-F-N-P-E-F-H-Q-A-M-S-I-Q-E-S-P-D-H-E-S-N-T-V-M-F-V-M-Q-K-G-Y-E-L-N-G-R-V-I-R-P-A-M-V-M-V-A-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-K-S-K-Q-K-A-G-S-N-T-I-A-L-N-K-K-A-R-H-E-Y-F-I-E-D-E-I-E-A-G-L-E-L-Q-G-W-E-V-K-A-L-R-Q-G-K-A-N-I-S-E-S-Y-V-F-M-R-D-G-E-A-F-V-S-G-M-T-I-T-P-L-N-Q-A-S-T-H-V-V-A-N-P-T-R-V-R-K-L-L-M-S-R-R-E-L-D-N-L-L-G-R-I-N-R-E-G-M-T-L-T-A-L-S-L-Y-W-S-R-S-W-V-K-I-K-I-G-V-A-K-G-K-K-L-H-D-K-R-T-D-L-K-E-K-D-W-A-R-E-K-A-R-V-M-K-S-A-L-R"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-H-F-E-L-F-G-L-P-S-Q-F-Q-L-D-G-S-L-L-S-S-K-F-R-E-L-Q-K-R-F-H-P-D-N-F-A-T-A-S-E-R-D-R-L-M-S-V-Q-K-A-A-Q-I-N-D-A-Y-Q-V-L-K-H-P-I-S-R-A-E-Y-I-L-A-E-Q-G-M-E-I-R-G-E-Q-Q-T-M-Q-D-P-M-F-L-M-E-Q-M-E-L-R-E-E-L-E-D-I-A-D-C-S-D-P-E-S-A-L-F-D-F-D-S-K-V-S-K-M-Y-K-Q-H-L-A-S-V-E-Q-E-L-N-D-G-L-W-A-E-A-A-D-R-V-R-K-L-K-F-I-A-K-L-K-N-E-I-E-L-V-E-D-K-L-L-G"} +{"text": "### FUNCTION Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins ### SEQUENCE -M-K-L-T-S-K-G-R-Y-A-V-T-A-M-L-D-V-A-L-H-S-Q-Q-N-P-V-P-L-A-D-I-S-E-R-Q-G-I-S-L-S-Y-L-E-Q-L-F-S-K-L-R-K-A-G-L-V-A-S-V-R-G-P-G-G-G-Y-R-L-G-A-D-A-H-S-I-A-I-G-T-V-I-A-A-V-D-E-S-V-D-A-T-K-C-Q-G-K-G-D-C-Q-G-G-T-R-C-L-T-H-T-L-W-R-D-L-S-S-R-I-S-D-F-L-N-N-I-T-L-G-E-L-M-T-D-N-E-V-L-E-I-S-D-R-Q-D-I-G-L-A-V-T-H-G-L-S-N-K-N-T-T-A-A-P-I-G-V-N-V-R-S"} +{"text": "### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-S-H-E-P-E-Y-R-D-W-Q-Q-I-V-E-L-I-R-S-S-V-D-S-Q-Q-H-E-M-L-L-T-M-L-M-T-P-D-E-R-E-S-L-T-A-R-V-N-I-L-N-E-L-L-K-G-E-L-S-Q-R-Q-I-S-Q-M-L-G-V-G-I-A-T-I-T-R-G-S-N-E-L-K-S-K-S-E-A-E-K-D-K-L-K-L-L-L-E-Q-V-A-Q-V-A-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-S-K-S-A-K-K-R-A-I-Q-A-E-K-R-R-Q-H-N-A-S-R-R-S-M-M-R-T-Y-M-K-K-T-V-A-A-I-E-A-G-D-K-E-A-A-T-A-A-F-A-V-V-T-P-I-L-D-R-M-A-T-K-G-L-I-H-K-N-K-A-A-R-H-K-S-R-F-A-A-Q-I-K-A-L"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-G-D-G-Y-R-L-N-V-G-I-V-I-C-N-N-H-G-Q-V-F-W-A-K-R-Y-G-Q-H-S-W-Q-F-P-Q-G-G-I-D-E-G-E-T-P-E-Q-A-M-F-R-E-L-Y-E-E-V-G-L-T-K-K-D-V-K-I-I-A-T-S-R-H-W-L-R-Y-K-L-P-K-R-L-V-R-W-D-S-K-P-V-C-I-G-Q-K-Q-K-W-F-L-L-R-L-E-C-D-E-S-R-I-N-M-Q-R-G-K-S-P-E-F-D-G-W-R-W-V-S-Y-W-Y-P-V-R-Q-V-V-S-F-K-R-D-V-Y-R-R-A-M-K-E-F-A-S-L-A-M-P-F-R-E-R-K-T-K-G-K-R-K-K-Q-Q-R-R-G"} +{"text": "### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-Q-G-I-Q-I-T-K-A-A-N-D-E-L-L-N-S-I-W-L-L-D-S-E-K-N-E-A-R-C-V-A-A-A-T-G-Y-E-A-D-Q-V-I-A-I-S-D-L-G-E-Y-E-S-R-E-V-A-I-E-T-A-P-R-I-E-G-G-Q-H-L-N-V-N-V-L-K-R-E-T-L-E-D-A-V-A-H-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-A-R-T-F-T-E-T-L"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-V-A-K-P-E-T-V-K-R-D-W-Y-V-V-D-A-E-G-K-T-L-G-R-L-A-S-E-I-A-S-R-L-R-G-K-H-K-A-E-Y-T-P-H-V-D-A-G-D-Y-I-I-V-I-N-A-E-K-V-A-V-T-G-N-K-A-K-D-K-V-Y-Y-R-H-S-E-F-P-G-G-L-K-S-I-T-F-E-K-L-I-D-R-K-P-E-M-V-L-E-L-A-V-K-G-M-L-P-R-G-P-L-G-R-A-M-Y-R-K-L-K-V-Y-A-G-A-E-H-N-H-V-A-Q-Q-P-Q-V-L-D-I"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-S-G-F-K-Q-H-T-G-L-V-V-P-L-D-A-A-N-V-D-T-D-A-I-I-P-K-Q-F-L-Q-K-V-S-R-L-G-F-G-K-H-L-F-H-D-W-R-F-L-D-D-A-G-E-R-P-N-P-E-F-V-M-N-A-P-R-Y-Q-G-A-S-I-L-L-A-R-E-N-F-G-C-G-S-S-R-E-H-A-P-W-A-L-A-D-Y-G-I-K-A-M-I-A-P-S-F-A-D-I-F-Y-G-N-S-I-N-N-Q-M-V-P-V-R-L-T-E-Q-E-V-D-E-L-F-Q-F-V-E-A-N-E-G-A-Q-I-E-V-D-L-E-A-L-K-V-R-A-N-G-K-E-Y-D-F-E-I-D-E-F-R-R-H-C-L-L-N-G-L-D-N-I-G-L-T-L-Q-H-E-D-K-I-A-E-Y-E-A-N-I-P-S-F-L-R"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-S-E-G-Q-T-L-R-L-E-K-L-D-V-E-T-G-A-T-V-E-F-D-K-V-L-L-V-A-N-G-E-D-I-K-V-G-A-P-L-V-E-G-G-K-I-V-A-E-V-V-Q-H-G-R-G-D-K-V-K-I-V-K-F-R-R-R-K-H-S-R-K-Q-Q-G-H-R-Q-W-F-T-E-V-K-I-T-G-I-N-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-R-N-S-E-K-Q-D-N-L-V-R-A-F-K-A-L-L-K-E-E-S-F-G-S-Q-G-E-I-V-D-A-L-K-Q-Q-G-F-E-S-I-N-Q-S-K-V-S-R-M-L-T-K-F-G-A-V-R-T-R-N-A-K-M-E-M-V-Y-C-L-P-A-E-L-G-V-P-T-V-S-S-S-L-R-E-L-V-L-D-I-D-H-N-A-A-L-V-V-I-H-T-G-P-G-A-A-Q-L-I-A-R-L-L-D-S-L-G-K-S-E-G-I-L-G-V-V-A-G-D-D-T-I-F-I-T-P-T-M-P-V-S-T-E-Q-L-F-K-S-V-C-E-L-F-E-Y-T-G"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-A-V-I-A-L-T-A-I-Y-G-I-G-K-T-R-S-Q-A-I-L-A-E-V-G-I-A-E-D-V-K-I-S-E-L-T-E-E-Q-I-D-Q-L-R-D-G-V-A-K-Y-T-V-E-G-D-L-R-R-E-V-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-S-L-P-L-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-A-P-A-A-G-S-K-H-A-P-K-R-V-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-K-S-R-S-G-G-K-V-R-P-G-F-E-G-G-Q-M-P-L-K-Q-R-L-P-K-F-G-F-T-S-R-K-S-L-V-S-A-E-V-R-L-A-E-L-A-K-V-S-G-D-V-V-D-L-N-S-L-K-A-A-N-I-I-T-K-N-I-E-F-V-K-V-V-L-S-G-E-I-N-K-A-V-T-V-K-G-L-R-V-T-K-G-A-K-A-A-I-E-A-A-G-G-K-I-E-E"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-K-E-Q-Q-V-Q-A-N-D-L-Q-E-K-L-I-A-V-N-R-V-S-K-T-V-K-G-G-R-I-M-S-F-T-A-L-T-V-V-G-D-G-N-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-N-M-T-T-I-A-L-N-E-G-T-L-H-H-P-V-K-G-R-H-S-G-S-K-V-Y-M-Q-P-A-A-E-G-T-G-V-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-H-N-V-L-S-K-A-Y-G-S-T-N-P-I-N-I-V-R-A-T-I-D-A-L-G-S-M-K-S-P-E-M-V-A-A-K-R-G-L-T-V-E-A-I-S-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-A-S-R-I-R-R-A-T-R-A-R-R-K-I-A-E-L-G-A-T-R-L-V-V-H-R-T-P-R-H-V-Y-A-Q-V-I-A-A-N-G-S-E-V-I-A-A-A-S-T-V-E-K-A-I-R-E-Q-V-K-Y-T-G-N-V-D-A-A-K-A-V-G-K-A-V-A-E-R-A-L-E-K-G-V-T-A-V-A-F-D-R-S-G-F-Q-Y-H-G-R-V-A-A-L-A-E-S-A-R-E-A-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-A-I-P-A-G-V-E-V-K-L-N-G-Q-E-I-T-V-K-G-A-K-G-E-L-T-R-V-L-N-D-A-V-V-I-A-Q-E-E-N-N-L-T-F-G-P-K-E-G-V-A-N-A-W-A-Q-A-G-T-A-R-A-L-V-N-N-M-V-V-G-V-T-E-G-F-T-K-K-L-T-L-K-G-V-G-Y-R-A-A-I-K-G-N-A-V-G-L-T-L-G-F-S-H-P-V-E-H-E-L-P-A-G-I-K-A-E-C-P-S-Q-T-E-I-V-I-T-G-C-D-K-Q-L-V-G-Q-V-A-A-D-I-R-S-Y-R-Q-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-N-V-R-T-K-E-A-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-S-D-M-L-T-R-V-R-N-G-Q-A-A-N-K-V-A-V-K-M-P-S-S-K-L-K-V-A-I-A-A-L-L-K-A-E-G-Y-I-V-D-F-A-V-E-G-E-A-K-P-E-L-E-V-T-L-K-Y-F-Q-A-K-P-V-I-E-Q-L-K-R-V-S-R-P-G-L-R-V-Y-K-K-K-D-E-L-P-S-V-M-G-G-L-G-I-A-I-V-S-T-S-K-G-L-M-S-D-R-A-A-R-K-A-G-L-G-G-E-I-I-C-Y-V-A"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-E-A-K-R-A-K-L-V-A-K-F-A-E-K-R-A-A-L-K-A-I-I-S-D-V-N-A-S-E-E-D-R-W-N-A-V-L-T-L-Q-S-L-P-R-D-S-S-A-S-R-Q-R-N-R-C-N-Q-T-G-R-P-H-G-Y-L-R-K-F-G-L-S-R-I-K-V-R-E-A-C-M-K-G-E-I-P-G-L-R-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-K-S-S-V-V-A-E-L-T-K-Q-F-S-Y-T-S-V-M-Q-V-P-R-I-E-K-I-T-L-N-M-G-V-G-E-A-I-N-D-K-K-L-L-E-N-A-A-S-D-M-A-T-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-V-A-G-F-K-I-R-E-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-D-F-L-E-R-L-I-N-I-A-L-P-R-V-R-D-F-R-G-V-S-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-F-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-S-A-G-T-D-E-E-G-R-A-L-L-A-A-F-N-F-P-F-R-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-N-D-E-V-I-V-L-A-G-K-D-K-G-K-K-G-K-V-T-K-V-L-A-T-G-K-V-I-V-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-L-G-I-Q-G-G-I-V-E-Q-E-A-A-I-D-V-S-N-V-A-I-F-N-A-A-T-G-K-A-D-R-I-G-F-R-F-E-D-G-K-K-V-R-F-F-K-S-N-G-E-T-V-S-N"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-M-L-D-A-A-D-N-S-G-A-R-S-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-H-I-G-D-V-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-D-V-M-K-A-V-V-V-R-T-R-K-G-V-R-R-P-D-G-S-V-I-R-F-D-R-N-A-C-V-L-L-N-N-T-T-E-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-G-D-K-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-V-K-R-T-Q-Q-G-R-V-V-S-D-K-M-D-K-S-I-T-V-A-I-E-R-F-V-K-H-P-I-Y-G-K-F-V-K-R-T-T-K-V-H-A-H-D-E-N-N-E-C-G-I-G-D-T-V-E-I-A-E-C-R-P-L-S-K-T-K-S-W-T-L-V-K-V-V-E-K-A-K-M"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-V-Q-T-G-R-N-R-G-L-A-K-G-T-D-V-S-F-G-E-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-H-V-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-E-V-R-Q-G-K-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-K-V-M-Y-E-M-G-G-V-P-E-E-L-A-R-E-A-F-R-L-A-A-R-K-L-P-F-K-T-T-F-V-T-K-Q-V-M"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-I-A-K-H-N-F-A-R-I-S-P-Q-K-A-R-L-V-A-D-L-I-R-G-K-S-V-D-Q-A-L-E-I-L-T-F-S-N-K-K-A-A-A-L-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-E-G-A-D-I-D-D-L-N-V-A-K-I-F-V-D-E-G-P-T-M-K-R-I-M-P-R-A-K-G-R-A-D-R-I-L-K-R-S-S-H-I-T-V-V-V-A-D-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-V-E-K-A-V-E-S-G-D-K-K-P-I-K-T-W-S-R-R-S-M-I-I-P-T-M-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-F-V-T-D-E-M-I-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-A-A-D-K-K-A-K-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-T-E-E-R-I-L-K-V-L-R-A-P-H-I-S-E-K-A-T-M-A-A-E-K-A-N-T-I-V-F-K-V-A-K-D-A-T-K-K-E-I-K-A-A-V-E-K-L-F-E-V-E-V-K-S-V-N-T-L-I-T-K-G-K-T-K-R-Q-G-L-R-Q-G-R-R-S-D-V-K-K-A-Y-V-T-L-K-E-G-Q-D-L-D-F-V-G-G-A-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA It is important during the early stages of 50S assembly It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-E-L-M-V-K-G-A-D-A-L-T-V-S-E-T-T-F-G-R-E-F-N-E-A-L-V-H-Q-V-V-V-A-Y-A-A-G-A-R-Q-G-T-R-A-Q-K-T-R-S-E-V-S-G-G-G-A-K-P-W-R-Q-K-G-T-G-R-A-R-A-G-T-I-R-S-P-I-W-R-T-G-G-V-T-F-A-A-K-P-Q-D-H-S-Q-K-V-N-K-K-M-Y-R-G-A-M-K-S-I-L-S-E-L-V-R-Q-E-R-L-I-V-V-D-N-F-S-V-E-A-P-K-T-K-E-L-V-A-K-L-K-E-L-E-L-T-D-A-L-I-V-T-S-E-V-D-E-N-L-F-L-A-A-R-N-L-Y-K-V-D-A-R-D-V-A-G-I-D-P-V-S-L-I-A-F-D-K-V-V-M-T-A-E-A-V-K-Q-V-E-E-M-L-A"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-G-I-H-P-E-Y-K-A-V-N-A-T-C-S-C-G-N-S-F-E-F-N-S-T-L-G-K-E-S-I-H-L-D-V-C-D-K-C-H-P-F-Y-T-G-K-Q-R-I-V-D-T-G-G-R-V-D-R-F-N-K-R-F-G-A-L-S-S-G-K-K"} +{"text": "### FUNCTION Globally modulates RNA abundance by binding to RNase E and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome Modulates RNA-binding and helicase activities of the degradosome ### SEQUENCE -M-E-Y-N-T-S-A-L-C-D-I-Y-L-D-Q-V-D-V-V-E-P-M-F-S-N-F-G-G-R-A-S-F-A-G-Q-I-T-T-I-K-C-F-E-D-N-S-L-I-R-E-T-L-E-Q-D-G-L-G-R-V-L-L-I-D-G-G-G-S-L-R-K-A-L-I-D-A-E-I-A-A-I-A-E-E-N-E-W-E-G-I-V-V-Y-G-C-V-R-E-V-D-E-L-E-D-M-N-L-G-I-Q-A-L-A-S-I-P-V-G-A-A-N-Q-G-I-G-E-L-D-V-P-V-N-F-G-G-V-S-F-L-P-E-D-Y-I-Y-A-D-N-T-G-I-I-L-S-P-E-P-L-N-I-D-L-E-L-D-D-T-V-E-E"} +{"text": "### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-F-E-V-L-E-Q-L-E-S-K-I-Q-T-A-V-D-T-I-T-L-L-Q-M-E-V-E-E-L-K-E-D-K-V-K-L-E-A-E-A-N-E-L-R-S-Q-R-E-D-L-E-Q-K-A-Q-Q-A-Q-Q-E-H-A-Q-W-Q-E-R-I-R-A-L-L-G-K-M-D-E-V-E"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-D-A-V-E-K-V-G-N-R-F-D-L-V-L-I-A-A-R-R-A-R-Q-M-Q-T-G-G-K-D-A-L-V-P-E-E-N-D-K-P-T-V-I-A-L-R-E-I-E-E-G-L-I-T-K-E-V-L-D-A-R-E-R-Q-E-Q-Q-E-Q-E-A-A-E-L-A-A-V-S-S-I-A-H-N-R"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-K-T-K-L-I-T-R-E-G-Y-N-K-L-K-Q-E-H-D-Y-L-W-N-E-K-R-P-E-I-T-K-I-V-T-W-A-A-S-L-G-D-R-S-E-N-A-D-Y-T-F-N-K-R-L-L-R-Q-I-D-R-R-V-R-F-L-R-K-F-L-P-E-V-T-I-V-D-Y-S-P-Q-Q-E-G-K-V-F-F-G-A-W-V-E-I-E-N-E-A-G-D-V-K-K-F-R-I-V-G-P-E-E-I-Y-G-D-A-K-D-Y-I-S-I-D-S-P-M-A-R-A-M-L-K-K-Q-V-D-E-E-F-T-V-R-T-P-E-G-D-K-E-W-F-I-N-S-I-E-Y-N-K-Q-S-A-E-S"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-S-N-I-T-I-T-E-T-A-Q-T-H-F-A-N-L-L-G-Q-Q-P-E-G-T-N-I-R-I-F-V-V-N-P-G-T-Q-N-A-E-C-G-V-S-Y-C-P-P-E-A-V-E-A-T-D-T-E-I-P-Y-A-G-F-S-A-Y-V-D-E-L-S-L-P-F-L-E-D-A-E-I-D-F-V-T-D-K-M-G-S-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-S-D-D-A-P-L-V-E-R-V-E-Y-V-I-Q-T-Q-V-N-P-Q-L-A-G-H-G-G-H-V-N-L-V-E-I-T-E-A-G-V-A-I-V-A-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-E-G-I-E-K-E-L-L-N-Q-F-V-G-E-L-T-A-V-R-D-A-T-E-H-D-R-G-D-H-S-Y-Y"} +{"text": "### FUNCTION A GTPase-activating protein that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-S-R-K-K-K-S-R-K-P-G-A-A-G-A-P-E-F-V-V-T-R-N-R-T-E-S-D-V-E-G-R-L-R-K-R-A-K-K-R-K-G-L-K-T-G-S-R-N-S-E-V-N-E-Q-K-K-Q-S-S-E-Q-N-R-D-P-R-L-G-S-K-K-K-I-P-L-I-V-E-P-V-K-K-M-T-K-Q-E-R-R-L-S-A-E-Q-E-L-E-M-L-E-N-D-A-Q-L-N-V-L-L-D-R-I-E-A-G-E-N-L-G-T-G-L-Q-K-Y-V-D-E-K-L-D-R-I-E-K-L-M-D-Q-L-G-L-L-E-P-E-E-E-E-D-F-T-A-S-S-A-K-G-S-R-N-D-D-D-L-L-A-D-F-D-D-I-N-F-D-D-Y-K-G"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-W-E-L-V-L-I-S-V-V-G-L-V-V-L-G-P-E-R-L-P-H-A-I-R-S-V-S-R-F-I-G-A-A-K-N-M-A-N-S-V-K-D-E-L-S-H-E-L-K-V-Q-E-L-Q-E-N-L-R-K-A-E-Q-M-G-M-E-D-L-S-P-E-L-K-S-S-V-E-E-L-K-K-A-A-Q-S-V-N-R-P-Y-A-D-K-A-Q-S-E-T-E-T-A-K-A-E-P-V-T-E-S-A-E-K-V-E-E-I-K-V-S-A-A-D-K-K-A-E"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-I-S-V-W-Q-L-L-I-I-A-V-I-V-V-L-L-F-G-T-K-K-L-R-G-I-G-G-D-L-G-S-A-V-K-G-F-K-K-A-M-S-D-E-D-S-A-K-N-E-K-D-A-D-F-E-P-K-S-L-E-K-Q-Q-Q-K-E-A-A-P-E-T-K-K-D-K-E-Q-A"} +{"text": "### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-S-F-N-P-E-L-A-T-K-T-L-E-A-E-G-L-R-C-P-E-P-V-M-M-V-R-K-T-I-R-N-M-Q-D-G-E-V-L-L-V-K-A-D-D-P-S-T-T-R-D-I-P-S-F-C-R-F-M-D-H-Q-L-I-A-A-Q-T-E-Q-L-P-Y-Q-Y-L-I-K-K-G-L-E"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-T-Y-A-F-N-R-E-L-R-L-L-T-P-E-H-Y-Q-N-V-F-Q-Q-A-H-R-A-G-S-P-H-F-T-I-I-A-R-N-N-K-L-S-H-P-R-L-G-L-A-V-P-K-K-Q-I-K-T-A-V-G-R-N-R-F-K-R-L-A-R-E-S-F-R-N-S-Q-H-Q-L-P-N-K-D-F-V-V-I-A-K-K-S-A-Q-D-L-S-N-E-E-I-F-K-L-F-D-K-L-W-Q-R-L-S-R-P-S-R-G"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-S-R-D-F-S-R-E-K-R-L-L-T-P-R-H-F-K-A-V-F-D-S-P-T-G-K-V-P-G-K-N-L-L-L-L-A-R-N-N-D-L-D-H-P-R-L-G-L-V-I-G-K-K-S-V-K-L-S-V-E-R-N-R-L-K-R-L-M-R-E-S-F-R-Q-H-Q-D-S-L-V-G-W-D-I-V-I-V-A-R-K-G-L-G-D-V-E-N-P-E-L-I-Q-H-F-G-K-L-W-K-R-L-A-R-S-R-P-T-P-E-E-K-S-E-P-A-G-V-D-S-T-D-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-I-N-A-T-L-I-G-Q-S-V-A-F-F-I-F-V-L-F-C-M-K-Y-V-W-P-P-V-I-A-A-L-H-E-R-Q-K-K-I-A-D-G-L-D-A-A-S-R-A-A-R-D-L-E-L-A-Q-D-K-V-G-Q-Q-L-R-E-A-K-A-Q-A-A-E-I-I-E-Q-A-K-K-R-G-T-Q-I-V-D-E-A-R-E-T-A-R-V-E-A-D-R-V-K-A-Q-A-Q-A-E-I-E-Q-E-L-N-G-V-K-D-A-L-R-A-Q-L-G-S-L-A-V-N-G-A-E-K-I-L-G-A-T-I-D-Q-N-A-H-A-E-L-V-N-K-L-A-A-E-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-L-T-T-L-A-R-P-Y-A-K-A-A-F-E-H-A-Q-A-H-Q-Q-L-A-N-W-S-A-M-L-G-L-A-A-A-V-S-Q-D-D-T-M-Q-R-M-L-K-A-P-R-V-T-S-A-Q-K-A-T-T-F-I-E-V-C-G-E-K-F-D-A-K-A-Q-N-F-I-H-V-V-A-E-N-D-R-L-P-L-L-P-E-I-A-E-L-F-D-L-Y-K-A-E-Q-E-K-S-V-D-V-D-V-T-S-A-F-A-L-N-Q-E-Q-Q-D-K-L-A-K-V-L-S-A-R-L-G-R-E-V-R-L-H-A-A-E-D-A-S-L-I-G-G-V-V-I-R-A-G-D-L-V-I-D-G-S-V-R-G-K-I-A-K-L-A-E-A-L-K-S"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-T-V-H-C-D-I-V-S-A-E-G-E-I-F-S-G-L-V-E-M-V-I-A-H-G-N-L-G-D-I-G-I-A-P-G-H-A-P-L-I-T-D-L-K-P-G-P-I-R-L-I-K-Q-G-G-E-A-E-V-F-Y-I-S-G-G-F-L-E-V-Q-P-N-M-V-K-V-L-A-D-T-V-Q-R-A-A-D-L-D-E-A-S-A-Q-A-A-V-K-A-A-E-K-A-L-N-E-K-G-A-D-F-D-Y-G-S-A-T-A-R-L-A-E-A-A-A-Q-L-R-T-V-Q-Q-I-R-K-K-F-G-G"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-T-Q-H-S-P-A-F-V-T-P-D-W-L-E-R-E-Q-L-T-D-T-P-T-P-V-F-F-G-W-L-F-N-Q-Q-S-L-T-R-R-L-D-R-L-S-D-G-G-F-D-I-V-P-L-S-E-G-W-Q-A-L-R-D-D-E-C-A-A-L-G-L-P-A-A-S-E-G-W-V-R-E-V-Y-L-R-G-N-G-E-N-W-V-F-A-R-S-V-A-A-R-D-A-L-Q-H-G-G-L-H-M-D-E-L-G-T-R-S-L-G-A-L-L-F-S-D-P-A-F-D-R-G-T-L-Q-V-C-H-Y-P-Q-S-W-L-P-D-A-D-A-V-S-G-L-W-A-R-R-S-Q-F-S-R-G-A-L-S-V-L-V-A-E-V-F-L-P-A-L-W-N-A-I-H-N-K-D-H-A"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-T-D-Q-P-N-N-G-A-V-A-N-E-E-N-G-P-Q-F-S-L-Q-R-I-Y-V-R-D-L-S-F-E-A-P-K-S-P-A-I-F-R-Q-E-W-T-P-T-V-S-L-D-L-N-T-R-Q-K-P-L-E-G-D-F-Y-E-V-V-L-T-L-S-V-T-V-N-N-G-E-E-V-A-F-I-V-E-V-Q-Q-A-G-I-F-L-I-K-G-L-D-D-A-A-M-S-H-T-L-G-A-F-C-P-N-I-L-F-P-Y-A-R-E-A-I-D-N-L-V-V-R-G-S-F-P-A-L-M-L-A-P-V-N-F-D-A-L-Y-A-Q-E-L-Q-R-M-Q-E-A-G-E-T-P-M-P-T-V-Q"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-P-D-G-F-R-P-N-V-G-I-I-L-T-N-D-A-G-Q-V-L-W-A-R-R-I-N-Q-D-A-W-Q-F-P-Q-G-G-I-N-P-Q-E-T-P-E-D-A-L-Y-R-E-L-N-E-E-V-G-L-E-R-H-D-V-Q-I-L-A-C-T-R-G-W-L-R-Y-R-L-P-Q-R-L-V-R-T-H-S-Q-P-L-C-I-G-Q-K-Q-K-W-F-L-L-R-L-I-S-N-E-Q-R-V-R-M-D-L-T-G-K-P-E-F-D-G-W-R-W-V-S-Y-W-Y-P-L-G-Q-V-V-T-F-K-R-E-V-Y-R-R-A-L-K-E-L-A-P-R-L-L-S-R-D"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-I-F-D-W-K-H-W-I-V-I-L-I-V-V-V-L-V-F-G-T-K-K-L-K-G-L-G-T-D-V-G-E-S-I-K-G-F-R-K-A-M-H-D-D-D-K-P-A-E-Q-P-A-P-Q-P-Q-Q-A-Q-P-A-P-Q-G-S-P-L-N-Q-P-H-T-I-D-A-Q-A-H-K-V-D-E-P-I-R-K-D-Q-V"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-D-I-H-P-V-Y-E-A-I-D-A-T-C-S-C-G-N-V-I-K-T-R-S-T-L-T-G-P-L-S-L-D-V-C-N-E-C-H-P-F-Y-T-G-K-Q-K-T-L-D-I-G-G-R-V-D-K-F-K-S-R-F-G-A-F-G-A-T-K-A-K-Q-D"} +{"text": "### FUNCTION Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'--3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism ### SEQUENCE -M-E-T-L-S-F-E-F-P-A-G-Q-P-P-K-G-R-A-L-V-G-V-V-G-S-G-D-L-E-V-L-L-E-P-G-Q-P-G-K-L-S-I-Q-V-V-T-S-V-N-G-A-S-L-R-W-K-H-L-F-E-R-M-F-D-G-Q-T-P-P-A-L-S-I-D-I-H-D-F-G-A-T-P-G-V-V-R-L-R-L-E-Q-G-F-E-E-I-G-H-D"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-S-L-P-N-P-A-E-L-I-R-Q-M-A-T-D-L-N-A-H-L-S-K-R-G-I-S-D-P-R-F-I-G-I-R-T-G-G-V-W-V-A-Q-A-L-L-E-A-L-N-N-P-S-P-L-G-T-L-D-V-S-F-Y-R-D-D-F-S-Q-N-G-L-H-P-Q-V-R-P-S-E-L-P-F-E-I-E-G-Q-H-L-V-L-I-D-D-V-L-M-S-G-R-T-V-R-A-A-L-N-E-L-F-D-Y-G-R-P-A-S-V-T-L-V-C-L-L-D-L-N-A-G-E-L-P-I-R-P-N-V-V-G-A-T-L-S-L-A-P-N-E-R-I-K-L-S-G-P-E-P-L-A-L-E-L-Q-D-L-S-T-A-L"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-A-L-R-L-L-L-G-I-D-Y-G-T-K-Q-I-G-V-A-V-G-Q-A-I-T-G-Q-A-R-E-L-C-T-L-K-A-Q-N-G-V-P-D-W-D-K-V-Q-A-L-I-N-E-W-K-P-D-A-I-V-V-G-L-P-L-N-M-D-G-T-P-S-E-M-S-A-R-A-E-K-F-S-R-K-L-N-G-R-F-G-V-T-V-Y-T-H-D-E-R-L-T-T-F-E-A-K-G-E-R-M-A-R-G-G-Q-K-G-S-Y-R-D-N-P-V-D-A-I-A-A-A-L-L-L-Q-G-W-L-D-E-H-P-E-L-L-N-V"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-Q-N-K-Q-N-L-I-W-I-D-L-E-M-T-G-L-D-P-D-T-D-V-I-I-E-M-A-T-I-I-T-D-S-E-L-N-T-L-A-E-G-P-V-I-A-V-H-Q-S-D-E-T-L-A-K-M-D-E-W-N-T-R-Q-H-G-G-S-G-L-T-Q-R-V-R-E-S-T-I-S-M-A-D-A-E-A-Q-T-L-A-F-I-K-L-W-V-P-E-R-S-S-P-I-C-G-N-S-I-C-Q-D-R-R-F-L-Y-R-H-M-P-A-L-E-N-Y-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-A-A-R-W-A-P-E-L-K-F-K-K-G-S-T-H-L-A-L-D-D-I-R-E-S-I-A-E-L-R-F-Y-R-E-H-F-I-K-P"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-S-K-G-H-S-L-Q-D-P-Y-L-N-T-L-R-K-E-K-V-G-V-S-I-Y-L-V-N-G-I-K-L-Q-G-T-I-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-V-R-P-I-R-L-P-S-A-T-D-A-D-G-A-D-A-E-P-G-N-A"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-I-F-L-V-H-P-D-Q-S-E-Q-V-G-G-M-V-E-R-Y-T-K-L-I-E-E-D-G-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-A-I-N-N-V-H-K-A-H-Y-V-M-L-N-V-E-C-T-G-K-A-L-A-E-L-E-D-N-F-R-Y-N-D-A-V-I-R-N-L-V-I-R-R-D-E-A-V-T-G-Q-S-E-M-L-K-A-E-E-N-R-S-E-R-R-E-R-R-D-R-P-E-H-S-D-S-A-D-G-D-D-G-D-N-S-D-V-S-D-N-A-D-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-F-F-R-R-R-K-F-C-R-F-T-A-E-D-V-K-E-I-D-Y-K-D-L-N-T-L-K-A-Y-V-S-E-T-G-K-I-V-P-S-R-I-T-G-T-K-A-R-Y-Q-R-Q-L-A-T-A-I-K-R-A-R-F-L-A-L-L-A-Y-T-D-S-H-G-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-L-I-L-L-E-K-V-A-N-L-G-N-L-G-D-K-V-N-V-K-A-G-Y-G-R-N-Y-L-L-P-Y-G-K-A-T-A-A-T-A-A-N-V-A-A-F-E-E-R-R-A-E-L-E-K-L-A-A-D-K-K-A-S-A-E-T-R-A-A-Q-L-A-E-L-E-V-T-I-T-A-T-A-G-D-E-G-K-L-F-G-S-I-G-T-H-D-I-A-D-A-L-T-A-S-G-V-E-V-A-K-S-E-V-R-L-P-N-G-T-I-R-N-V-G-E-F-D-V-A-V-H-L-H-S-D-V-E-A-T-V-R-V-V-V-V-A-A"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-L-V-I-H-N-R-I-E-P-Q-A-E-W-A-A-E-L-H-L-N-F-E-A-R-S-K-S-R-L-R-C-F-S-A-E-N-E-D-V-G-L-F-L-Q-R-G-Q-S-P-L-R-D-G-E-F-L-Q-A-E-D-G-R-I-V-R-V-C-A-R-P-E-K-L-M-H-V-T-C-S-S-T-F-E-L-T-R-A-A-Y-H-L-G-N-R-H-V-A-L-Q-V-G-D-G-W-L-R-L-L-D-D-Y-V-L-K-A-M-L-D-Q-L-G-A-T-T-E-A-I-E-A-P-F-Q-P-E-H-G-A-Y-G-G-G-H-H-H-S-R-A-G-E-E-D-F-N-Y-P-P-R-M-H-Q-F-G-V-R-K"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-R-L-R-L-I-A-V-G-S-R-M-P-K-W-V-E-E-G-W-H-E-Y-A-K-R-M-P-S-E-L-A-L-E-L-V-E-I-P-L-N-T-R-G-K-N-A-D-V-A-R-F-I-R-Q-E-G-E-A-M-L-A-K-V-Q-P-G-E-R-I-V-T-L-E-V-Q-G-K-P-W-S-T-E-Q-L-A-V-E-L-D-R-W-R-L-D-A-R-T-V-N-L-M-V-G-G-P-E-G-L-A-P-E-V-C-A-R-S-E-Q-R-W-S-L-S-P-L-T-L-P-H-P-L-V-R-I-L-I-G-E-Q-M-Y-R-A-W-T-V-L-S-G-H-P-Y-H-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-L-E-L-D-L-Q-I-A-S-E-T-P-A-P-D-E-A-R-F-R-L-W-C-E-M-G-L-R-Q-R-S-A-D-S-E-L-T-I-R-L-V-D-E-T-E-G-R-E-L-N-H-T-W-R-H-K-N-Y-A-T-N-V-L-S-F-P-A-D-V-P-D-D-M-L-D-I-P-L-L-G-D-L-V-I-C-V-P-V-V-N-R-E-A-A-E-Q-G-K-S-I-D-A-H-W-A-H-M-V-I-H-G-C-L-H-L-L-G-Y-D-H-I-D-D-E-E-A-E-E-M-E-A-L-E-R-T-L-L-E-E-L-G-Y-P-D-P-Y-A-D-D-E-S-A-D-H-P-H-S-D-T-P-S-K-D-H-E"} +{"text": "### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate May function as an ADP-ribosylase ### SEQUENCE -M-N-K-K-Q-R-D-E-I-S-K-L-L-S-Y-V-L-R-H-A-P-E-S-M-G-L-T-L-D-R-D-G-W-C-E-V-D-E-L-V-G-K-A-N-A-N-G-H-S-F-D-R-Q-A-L-E-E-V-V-E-T-N-E-K-K-R-F-T-L-S-E-D-G-Q-R-I-R-A-A-Q-G-H-S-T-E-Q-V-Q-V-Q-H-I-E-K-E-P-P-A-W-L-Y-H-G-T-A-S-R-F-M-A-S-I-E-T-Q-G-L-I-A-G-S-R-H-H-V-H-L-T-E-D-P-E-T-A-L-S-V-G-K-R-Y-G-Q-P-V-L-L-A-V-D-A-K-G-M-F-E-A-G-V-Q-F-F-Q-A-D-N-G-V-W-L-V-E-A-V-P-I-E-W-L-T-K-V-A-D-T-V-S"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-V-L-T-E-F-K-A-F-A-V-K-G-N-V-V-D-M-A-V-G-I-I-I-G-A-A-F-G-K-I-V-S-S-F-V-G-D-V-I-M-P-P-L-G-L-L-I-G-G-V-D-F-S-D-L-A-V-T-L-R-P-A-Q-G-T-A-P-A-V-L-L-A-Y-G-K-F-I-Q-T-V-I-D-F-I-I-V-A-F-A-I-F-M-G-V-K-A-I-N-R-L-K-R-E-E-A-K-A-P-T-L-P-P-T-P-S-K-Q-E-V-L-L-S-E-I-R-D-L-L-K-A-Q-N-T-P-A-A-P-I-T-V-D-P-A-R-T-L"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-L-K-K-H-P-T-G-T-I-A-Q-N-K-K-A-R-H-D-Y-F-I-E-H-K-F-E-A-G-L-V-L-S-G-W-E-V-K-S-L-R-A-T-K-V-Q-L-V-D-S-Y-V-L-L-K-D-G-E-A-W-L-M-G-C-H-I-T-P-L-K-T-A-S-T-H-V-I-A-D-P-T-R-T-R-K-L-L-L-N-Q-R-E-L-E-K-L-T-S-S-V-Q-Q-K-G-Y-A-C-V-A-L-S-I-Y-W-K-Q-H-L-I-K-C-E-I-A-L-G-K-G-K-K-E-Y-D-K-R-H-T-E-R-E-R-D-S-D-R-E-L-Q-R-A-V-R-T-K-G-K-D-D"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-D-E-Q-N-L-D-A-Q-A-Q-D-Q-A-A-E-A-G-A-G-D-E-L-T-T-R-V-Q-V-L-E-E-Q-L-A-A-A-Q-D-Q-S-L-R-V-A-A-D-L-Q-N-V-R-R-R-A-E-Q-D-V-E-K-A-H-K-F-A-L-E-K-F-A-G-D-L-L-P-I-I-D-S-L-E-R-G-L-D-L-S-N-P-D-D-E-S-I-R-P-M-R-E-G-I-E-L-T-L-K-M-F-Q-D-T-L-K-R-Y-Q-L-E-A-I-D-P-H-G-Q-P-F-S-A-D-Q-H-Q-A-M-A-M-Q-E-S-A-D-V-E-P-N-T-V-L-K-V-F-Q-K-G-Y-Q-L-N-G-R-L-L-R-P-A-M-V-V-V-S-K-A-P-S-P-A-T-P-S-I-N-E-Q-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-I-K-Y-P-M-T-V-Q-G-A-R-A-L-E-E-E-L-T-H-L-T-K-V-I-R-P-K-L-S-Q-D-I-G-T-A-R-E-L-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-Q-Q-G-M-V-E-A-R-I-R-D-I-E-G-R-M-Q-N-A-V-V-I-D-V-T-T-I-A-H-T-G-K-V-I-F-G-T-T-V-E-I-A-N-V-E-T-D-E-S-V-V-Y-Q-I-V-G-E-D-E-A-D-I-K-K-G-K-I-S-V-G-S-P-I-A-R-A-L-I-A-K-E-E-G-D-V-V-V-V-K-T-P-S-G-V-I-E-Y-E-I-I-E-V-R-H-I"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-Y-E-G-V-Q-V-S-S-K-L-E-Q-L-Q-G-L-L-A-P-V-V-V-A-L-G-Y-Q-C-W-G-I-D-F-S-S-Q-G-K-H-S-V-L-R-I-Y-I-D-K-E-G-G-V-L-V-D-D-C-A-I-V-S-R-Q-I-S-G-V-L-D-V-E-D-P-I-S-T-E-Y-T-L-E-V-S-S-P-G-M-E-R-P-L-F-T-I-E-Q-F-A-L-Y-A-G-E-Q-V-R-I-K-L-R-S-P-F-E-G-R-R-N-F-Q-G-L-L-R-G-V-E-E-Q-D-V-V-V-Q-V-E-D-H-E-F-L-L-P-I-D-L-I-D-K-A-N-I-I-P-T-F-D"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-E-Y-S-R-T-Q-R-I-G-D-Q-M-Q-R-E-L-A-Q-L-I-R-R-E-I-K-D-P-R-V-G-L-V-T-I-T-A-V-D-V-S-R-D-V-G-H-A-K-I-F-M-T-V-M-G-Q-D-N-A-E-D-I-A-Q-T-I-K-V-L-N-A-A-A-G-F-L-R-M-Q-L-A-R-E-M-K-L-R-S-V-P-Q-L-H-F-H-Y-D-E-S-V-V-R-G-A-H-L-S-A-L-I-E-R-A-V-A-Q-D-S-Q-H-Q-E-G-P-A-S-P-D-A-K-P-E-S-T-E-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-S-V-E-E-K-A-Q-I-V-T-D-Y-Q-Q-A-V-G-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-N-I-N-K-L-Q-G-H-F-K-A-N-G-K-D-H-H-S-R-R-G-L-I-R-M-V-N-Q-R-R-K-L-L-D-Y-L-K-G-K-D-V-S-R-Y-S-A-L-I-G-R-L-G-L-R-R"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-A-L-E-R-S-D-V-E-K-I-A-H-L-A-R-L-G-L-N-D-A-D-I-P-R-T-T-E-A-L-N-S-I-L-G-L-V-D-Q-M-Q-A-V-D-T-T-G-I-E-P-L-A-H-P-L-E-A-T-Q-R-L-R-E-D-A-V-T-E-R-N-R-R-D-T-Y-Q-A-I-A-P-A-V-Q-D-G-L-Y-L-V-P-K-V-I-E"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-T-A-K-P-E-T-V-K-R-D-W-F-V-V-D-A-A-G-Q-T-L-G-R-L-A-T-E-I-A-S-R-L-R-G-K-H-K-P-E-Y-T-P-H-V-D-T-G-D-Y-I-V-V-I-N-A-E-Q-I-R-V-T-G-A-K-T-T-D-K-I-Y-Y-S-H-S-G-F-P-G-G-I-K-S-I-N-F-E-K-L-I-A-K-A-P-E-R-V-I-E-T-A-V-K-G-M-L-P-K-N-P-L-G-R-D-M-Y-R-K-L-K-V-Y-A-G-A-V-H-P-H-T-A-Q-Q-P-L-E-L-K-F"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-L-R-P-L-H-D-R-V-V-I-R-R-S-E-E-E-T-K-T-A-G-G-I-V-L-P-G-S-A-A-E-K-P-N-R-G-E-I-V-A-V-G-T-G-R-V-L-D-N-G-E-V-R-A-L-A-V-K-V-G-D-K-V-V-F-G-P-Y-S-G-S-N-T-V-K-V-D-G-E-D-L-L-V-M-S-E-N-E-I-L-A-V-V-E-G"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-P-A-V-L-D-T-P-V-A-I-R-R-T-A-M-D-L-L-A-R-R-E-H-G-R-V-E-L-T-R-K-L-R-Q-R-G-A-P-P-E-L-I-E-A-A-L-D-R-L-V-E-E-G-L-L-S-E-S-R-Y-L-E-S-F-V-S-Y-R-A-R-S-G-Y-G-P-A-R-I-R-E-E-L-N-Q-R-G-L-Q-R-A-D-V-E-R-A-L-K-E-C-G-V-N-W-Q-E-K-L-Q-E-V-W-Q-R-K-F-A-G-E-L-P-V-D-A-R-E-R-A-R-Q-G-R-F-L-S-Y-R-G-Y-P-L-D-M-I-G-R-L-L-S-G-R-G-G-D-D"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-N-I-F-D-F-F-R-D-R-K-K-E-S-T-A-S-V-A-K-E-R-L-Q-I-I-V-A-H-E-R-G-Q-R-S-T-P-D-Y-L-P-A-L-Q-K-E-L-V-E-V-I-R-K-Y-V-N-I-E-S-D-Q-V-Q-V-A-L-E-S-Q-G-S-C-S-I-L-E-L-N-I-T-L-P-D-R"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-P-S-L-L-L-A-S-S-S-P-Y-R-R-E-L-L-A-R-L-R-L-P-F-A-C-E-S-P-D-I-D-E-S-H-R-P-G-E-T-P-H-D-L-V-Q-R-L-A-R-E-K-A-E-A-L-A-S-E-Y-P-G-H-L-I-I-G-S-D-Q-V-A-V-L-D-G-Q-I-L-G-K-P-H-T-F-E-R-A-R-E-Q-L-T-A-A-S-D-T-R-V-T-F-L-T-G-L-A-L-L-N-S-S-T-G-E-C-Q-V-D-C-V-P-F-T-V-H-M-R-E-L-D-Q-A-S-I-E-R-Y-L-R-A-E-T-P-Y-D-C-A-G-S-F-K-A-E-G-L-G-V-S-L-F-R-S-T-Q-G-A-D-A-T-S-L-I-G-L-P-L-I-R-L-V-D-M-L-I-K-E-G-V-S-V-P"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-N-P-I-S-L-L-F-L-A-L-A-M-S-T-D-A-F-A-A-A-L-G-K-G-A-S-L-H-K-P-R-F-I-E-A-L-R-T-G-L-I-F-G-A-I-E-T-I-T-P-V-I-G-W-G-I-G-Q-V-A-A-R-F-A-E-S-W-D-H-W-I-A-F-T-L-L-L-V-L-G-L-H-M-I-Y-N-G-L-K-H-D-H-E-E-E-Q-E-K-P-G-S-H-S-F-W-I-L-A-V-T-A-F-A-T-S-I-D-A-L-A-V-G-V-G-L-A-F-V-D-V-N-I-M-V-A-A-L-A-I-G-L-A-T-T-V-M-V-T-I-G-V-M-L-G-R-V-L-G-T-M-V-G-K-R-A-E-I-V-G-G-I-V-L-I-V-V-G-T-T-I-L-Y-E-H-L-T-A-A-A"} +{"text": "### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate -ureidoglycolate, generating urea and glyoxylate Involved in the utilization of allantoin as nitrogen source ### SEQUENCE -M-R-T-L-T-I-E-P-L-T-K-D-A-F-A-P-F-G-D-V-I-E-T-D-G-S-D-H-F-M-I-N-N-G-S-T-M-R-F-H-R-L-A-E-V-D-T-A-Q-P-D-D-K-A-I-I-S-I-F-R-A-E-S-L-P-M-P-L-T-I-G-M-L-E-R-H-P-Q-G-S-Q-A-F-I-P-L-L-G-N-P-F-L-I-V-V-A-P-V-G-D-A-P-E-S-A-L-T-R-A-F-V-S-N-G-R-Q-G-V-N-Y-H-R-G-V-W-H-H-P-V-L-T-I-E-K-Q-D-D-F-L-V-V-D-R-S-G-S-G-N-N-C-D-E-H-Y-F-E-E-N-Q-R-L-V-L-D-P-N-P-Q-E-G"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-K-G-G-M-A-G-L-M-K-Q-A-Q-Q-M-Q-E-K-M-A-K-M-Q-E-E-L-A-N-A-E-V-T-G-Q-S-G-A-G-L-V-S-V-V-M-T-G-R-H-D-V-K-R-I-N-L-D-D-S-L-M-Q-E-D-K-E-V-L-E-D-L-I-A-A-A-V-N-D-A-V-R-K-I-E-Q-A-S-Q-D-K-T-A-S-M-T-A-G-M-Q-L-P-P-G-M-K-L-P-F"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-F-S-P-L-I-R-Q-L-I-D-A-F-R-V-L-P-G-V-G-Q-K-T-A-Q-R-M-A-L-Q-L-L-E-R-D-R-S-G-G-S-R-L-A-L-A-L-G-Q-A-M-D-G-V-G-H-C-R-L-C-R-T-L-T-E-E-E-L-C-P-Q-C-S-D-L-R-R-N-D-T-L-L-C-V-V-E-G-P-T-D-V-Y-A-V-E-Q-T-G-Y-R-G-R-Y-F-V-L-K-G-H-L-S-P-L-D-G-L-G-P-E-A-I-G-I-P-Q-L-M-E-R-I-S-Q-Q-A-T-F-T-E-V-I-L-A-T-N-P-T-V-E-G-E-A-T-A-H-Y-I-A-Q-L-L-H-D-K-G-L-V-A-S-R-I-A-H-G-V-P-L-G-G-E-L-D-L-V-D-G-G-T-L-A-H-S-F-A-G-R-K-P-I-A-L"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-K-V-G-E-S-I-N-I-G-D-E-I-T-V-T-I-L-G-V-Q-G-L-Q-V-R-L-G-I-N-A-P-K-N-V-S-V-H-R-E-E-I-Y-K-R-I-Q-A-E-L-A-P-N-Q-D-P-Q"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-H-A-F-S-K-I-R-L-T-F-N-Q-D-G-P-Q-S-H-E-D-D-S-A-G-I-A-V-Q-D-A-K-P-T-L-Q-A-P-P-M-Y-K-V-V-L-F-N-D-D-Y-T-P-M-D-F-V-V-E-V-L-E-V-F-F-N-L-N-R-E-L-A-T-K-V-M-L-A-V-H-T-E-G-R-A-V-C-G-L-F-T-R-D-I-A-E-T-K-A-A-Q-V-N-Q-Y-A-R-E-S-Q-H-P-L-L-C-E-I-E-K-D-G"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-E-D-S-F-E-M-E-G-T-V-A-D-T-L-P-N-T-M-F-R-V-E-L-E-N-G-H-V-V-T-A-H-I-S-G-K-M-R-K-N-Y-I-R-I-L-T-G-D-K-V-R-V-E-L-T-P-Y-D-L-S-K-G-R-I-T-Y-R-A-R"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-Q-T-I-L-A-V-S-I-A-G-I-A-G-T-L-L-R-F-A-A-G-T-W-V-S-A-N-W-P-R-Y-F-Y-A-A-T-L-A-V-N-I-V-G-C-L-I-I-G-V-L-Y-G-L-F-L-S-R-P-E-V-P-V-E-I-R-A-G-L-I-V-G-F-V-G-G-L-T-T-F-S-S-F-S-L-D-T-L-R-L-L-E-S-G-Q-V-P-L-A-L-G-Y-A-G-I-S-V-F-G-G-L-L-A-T-W-A-G-L-S-L-T-R-L"} +{"text": "### FUNCTION Inhibitor of the alkaline protease ### SEQUENCE -M-N-I-N-Y-F-V-R-I-V-P-V-A-V-V-L-L-V-G-I-S-G-A-S-M-A-M-S-L-K-L-P-N-P-A-E-L-S-G-Q-W-R-L-S-L-Q-G-K-A-D-D-A-C-E-L-Q-L-N-T-E-A-P-Q-L-T-G-D-V-A-C-A-A-K-W-L-H-E-P-P-A-G-W-F-P-T-P-D-G-L-A-L-T-D-N-Q-G-N-R-L-I-H-L-N-R-M-D-E-Q-T-Y-E-A-R-L-P-G-G-E-L-L-I-L-G-R-F-A-D"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-T-A-I-T-I-T-D-A-A-H-D-Y-L-A-D-L-L-E-K-Q-N-T-P-G-I-G-I-R-V-F-I-T-Q-P-G-T-Q-Y-A-E-T-C-I-A-Y-C-K-P-G-E-E-K-P-E-D-K-A-I-G-L-K-S-F-T-A-W-I-D-G-F-S-E-A-F-L-D-D-A-V-V-D-Y-A-T-D-R-M-G-G-Q-L-T-I-K-A-P-N-A-K-V-P-M-V-N-A-D-S-P-I-N-E-R-I-N-Y-Y-L-Q-T-E-I-N-P-G-L-A-S-H-G-G-Q-V-T-L-I-D-V-V-E-E-E-A-K-N-I-A-V-L-Q-F-G-G-G-C-Q-G-C-G-Q-A-D-V-T-L-K-E-G-I-E-R-T-L-L-E-R-I-P-E-L-S-G-V-R-D-V-T-D-H-T-Q-K-E-N-A-Y-Y"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-L-I-L-D-R-I-L-G-Q-A-S-D-P-A-L-A-D-R-L-H-D-L-S-H-A-G-Q-V-E-T-L-S-L-S-G-S-D-I-Q-R-H-R-L-R-L-A-S-D-R-G-T-D-C-A-I-R-L-E-R-H-Q-Q-L-R-N-G-S-V-L-M-L-D-S-Q-R-A-I-V-V-Q-M-Q-D-Q-H-Y-L-D-L-L-P-R-D-S-A-A-A-L-E-L-G-Y-F-A-G-N-M-H-W-A-V-R-F-A-G-D-T-L-Q-I-P-L-N-G-P-E-A-D-Y-L-E-R-L-A-P-M-L-A-D-G-R-V-R-R-A"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-G-A-L-T-K-A-E-M-A-E-R-L-Y-E-E-L-G-L-N-K-R-E-A-K-E-L-V-E-L-F-F-E-E-I-R-H-A-L-E-D-N-E-Q-V-K-L-S-G-F-G-N-F-D-L-R-D-K-R-Q-R-P-G-R-N-P-K-T-G-E-E-I-P-I-T-A-R-R-V-V-T-F-R-P-G-Q-K-L-K-A-R-V-E-A-Y-A-G-T-K-S"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-S-T-K-I-I-T-Q-G-G-H-E-A-L-K-K-E-L-D-Y-L-W-R-E-H-R-P-D-I-T-Q-K-V-A-W-A-A-S-L-G-D-R-S-E-N-A-D-Y-Q-Y-N-K-K-L-L-R-E-I-D-R-R-V-R-Y-L-R-K-R-L-E-D-M-R-V-V-Q-Y-S-P-E-Q-E-G-R-V-F-F-G-A-W-V-E-I-E-N-E-A-G-D-L-K-K-F-R-V-V-G-Y-D-E-I-Y-G-R-N-D-Y-I-S-I-D-S-P-M-A-R-A-L-L-K-K-E-V-G-D-E-V-L-V-N-T-P-E-G-E-K-L-W-F-V-N-S-I-V-Y-E-R"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-S-S-V-L-R-P-A-L-S-L-I-V-L-M-S-L-I-T-G-V-A-Y-P-L-V-V-T-G-V-A-Q-V-A-F-P-A-Q-A-N-G-S-L-L-Y-D-E-A-G-K-V-R-G-S-A-L-I-A-Q-S-F-T-G-D-E-W-F-Q-S-R-P-S-A-G-A-F-A-T-V-A-S-G-A-S-N-F-A-P-S-N-P-A-L-A-T-R-V-T-E-D-A-A-K-L-A-N-A-A-Q-G-P-V-P-L-A-L-L-T-T-S-G-S-G-L-D-P-H-L-S-P-E-A-I-A-W-Q-A-G-R-V-A-A-A-R-Q-L-P-L-D-K-L-Q-A-L-I-D-A-S-T-Q-R-P-L-I-G-P-P-V-V-N-V-L-T-L-N-M-S-L-N-Q-L-P-S-A-P-R-N-A-Q-L"} +{"text": "### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-S-E-P-I-E-S-L-T-V-D-A-V-L-D-A-T-G-L-F-C-P-E-P-V-M-M-L-H-Q-K-V-R-D-L-P-P-S-G-L-L-K-V-I-A-T-D-P-S-T-C-R-D-I-P-K-F-C-V-F-L-G-H-E-L-V-A-E-Q-A-E-E-S-T-F-L-Y-W-I-R-K-K-S-D"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-F-D-Q-S-N-F-K-S-L-I-R-P-V-V-D-F-P-K-P-G-V-V-F-R-D-I-T-P-L-F-Q-S-P-K-A-T-R-Q-V-I-D-S-F-V-Q-R-Y-I-D-A-D-F-S-H-I-G-V-M-D-A-R-G-F-L-I-G-S-V-V-A-Y-Q-L-N-K-P-L-V-L-F-R-K-Q-G-K-L-P-A-D-V-L-S-E-A-Y-Q-T-E-Y-G-E-A-Y-L-E-V-H-A-D-S-L-C-E-G-N-S-V-I-M-F-D-D-L-I-A-T-G-G-T-L-I-A-A-A-N-L-I-R-R-M-G-A-Q-V-H-E-A-A-A-I-I-D-L-P-E-L-G-G-S-K-R-L-N-D-L-N-I-P-T-F-C-L-T-E-F-A-L-D-E-Q"} +{"text": "### FUNCTION Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide ### SEQUENCE -M-P-H-S-N-I-S-S-T-P-R-Q-Q-L-T-E-R-V-L-Q-A-K-A-A-N-N-L-T-W-A-S-L-A-E-D-T-G-L-S-V-V-Y-V-T-A-A-L-L-G-Q-H-P-L-P-Q-A-V-A-E-V-V-A-E-R-L-G-L-D-R-D-A-V-V-E-L-Q-T-I-P-L-R-G-H-V-E-D-V-S-S-D-P-T-I-Y-R-F-H-E-M-V-Q-V-Y-G-T-T-L-K-A-L-V-H-E-Q-F-G-D-G-I-I-S-A-I-N-F-K-L-D-I-R-K-V-E-D-P-E-G-G-E-R-A-V-I-T-L-D-G-K-F-L-P-Y-K-P-F"} +{"text": "### FUNCTION Involved in tetrahydrobiopterin biosynthesis Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 May also have a positive regulatory role in the expression of phhA ### SEQUENCE -M-S-T-L-N-Q-A-H-C-E-A-C-S-A-G-A-P-Q-V-S-E-A-E-L-P-E-L-L-R-Q-I-P-D-W-N-I-E-V-R-D-S-V-M-Q-L-E-K-V-F-L-F-K-N-F-K-F-A-L-A-F-T-N-A-V-G-E-I-A-E-A-E-G-H-H-P-G-L-L-T-E-W-G-K-V-T-V-T-W-W-S-H-S-I-K-G-L-H-R-N-D-F-I-M-A-A-R-T-D-E-V-A-A-K-A-E-G-R-K"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-Q-F-I-D-F-I-P-L-L-L-F-F-I-V-Y-K-T-E-P-R-A-V-D-I-L-G-N-S-Y-T-F-G-G-I-F-S-A-T-A-M-L-I-I-S-S-V-V-V-Y-G-I-L-Y-I-K-Q-R-K-L-E-K-S-Q-W-L-T-L-V-A-C-L-V-F-G-S-L-T-L-A-F-H-S-E-T-F-L-K-W-K-A-P-V-V-N-W-L-F-A-V-A-F-A-G-S-H-F-I-G-D-R-P-L-I-Q-R-I-M-G-H-A-L-T-L-P-A-A-I-W-T-R-L-N-I-A-W-I-I-F-F-L-F-C-G-A-A-N-L-Y-V-A-F-T-Y-Q-E-F-W-V-D-F-K-V-F-G-S-L-G-M-T-L-I-F-L-V-G-Q-G-I-Y-L-S-R-H-L-H-D-T-T-P-N-T-P-K-S-E-D"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-T-G-K-E-L-K-P-G-T-V-I-R-L-E-N-D-P-W-L-V-Q-K-A-E-F-T-K-S-G-R-N-S-A-I-M-K-T-K-L-K-N-L-L-T-G-Y-K-T-E-I-V-Y-S-A-D-D-K-L-D-D-V-I-L-D-R-K-E-A-T-L-S-F-I-S-G-D-T-Y-T-F-M-D-T-T-D-Y-T-M-Y-E-L-N-A-E-D-I-E-S-V-L-P-F-V-E-E-G-M-T-D-V-C-E-A-V-F-F-D-E-R-L-V-S-V-E-L-P-T-T-I-V-R-Q-V-D-Y-T-E-G-S-A-R-G-D-T-S-G-K-V-M-K-P-A-K-L-K-N-G-T-E-L-S-V-A-D-F-I-E-I-G-D-M-I-E-I-D-T-R-E-G-G-S-Y-K-G-R-A-K"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-R-I-V-T-H-Q-G-L-L-S-S-K-D-V-E-L-A-I-K-T-M-L-E-Q-M-S-Q-C-L-A-T-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-A-P-R-V-G-R-N-P-K-T-G-Q-S-V-S-L-D-G-K-F-V-P-H-F-K-P-G-K-E-L-R-D-R-V-N-E-D-E-E-E-G-F"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-V-L-T-R-D-I-G-E-T-F-S-I-G-D-D-I-T-V-Q-I-L-G-V-N-G-N-Q-V-R-L-G-I-S-A-P-K-D-I-K-V-H-R-A-E-V-Y-K-R-I-A-N-K-L-S-Q-Q-A-A-Q-T-Q-P"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-R-N-I-L-K-M-G-D-E-R-L-L-R-I-A-P-P-V-P-A-E-M-F-G-S-S-E-L-E-T-L-I-A-D-M-F-E-T-M-H-S-V-G-G-V-G-L-A-A-P-Q-I-G-I-D-L-Q-L-V-I-F-G-F-E-R-S-E-R-Y-P-Q-A-E-A-V-P-Q-T-I-L-L-N-P-L-I-T-P-L-H-P-G-V-E-E-G-W-E-G-C-L-S-V-P-G-L-R-G-M-V-D-R-Y-Q-S-I-R-Y-E-G-F-D-P-D-G-Q-P-I-E-R-I-A-H-G-F-H-A-R-V-V-Q-H-E-C-D-H-L-I-G-R-L-Y-P-S-R-I-T-D-F-S-K-F-G-F-M-D-V-M-F-P-D-M-D-P-N-A-D-E"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-E-I-K-K-D-A-Q-T-R-M-Q-K-S-L-E-S-L-T-H-A-F-T-R-I-R-T-G-K-A-H-P-S-I-L-G-G-V-M-V-P-Y-Y-G-A-D-T-P-L-S-Q-V-A-N-V-T-V-K-D-S-R-T-L-Q-V-V-A-F-E-R-N-M-L-A-A-V-D-K-A-I-Q-S-S-G-L-G-F-N-P-T-N-L-G-E-L-L-L-I-S-M-P-A-L-T-E-E-T-R-K-G-F-T-K-Q-A-R-D-A-A-E-D-A-R-V-A-V-R-N-I-R-R-D-A-L-S-Q-L-K-D-L-V-K-D-K-E-I-S-E-D-E-E-R-R-A-A-D-D-V-Q-K-L-T-D-K-F-V-A-D-I-E-V-A-V-K-Q-K-E-A-D-L-M-A-V"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-T-N-K-I-I-L-A-L-E-A-E-Q-M-T-K-E-I-P-T-F-A-P-G-D-T-I-V-V-Q-V-K-V-K-E-G-D-R-A-R-L-Q-A-F-E-G-V-V-I-A-K-R-N-R-G-V-N-S-A-F-T-V-R-K-I-S-N-G-V-G-V-E-R-T-F-Q-T-Y-S-P-Q-I-D-S-M-A-V-K-R-R-G-D-V-R-K-A-K-L-Y-Y-L-R-D-L-S-G-K-A-A-R-I-K-E-K-L-S"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-N-A-T-P-A-S-A-D-D-L-I-V-I-G-K-I-Y-S-V-H-G-V-R-G-E-V-K-V-Y-S-F-T-D-P-I-G-N-L-L-D-Y-K-T-W-T-L-R-R-E-G-S-V-E-K-Q-V-E-L-V-S-G-R-L-Q-S-K-F-L-V-V-K-L-K-G-L-D-D-R-E-E-A-R-L-L-S-G-Y-E-I-C-V-P-R-N-L-F-P-D-L-D-D-G-E-Y-Y-W-Y-Q-L-E-G-L-K-V-I-D-Q-L-G-Q-L-L-G-K-I-D-H-L-L-E-T-G-S-N-D-V-M-V-V-K-P-C-A-G-S-L-D-D-R-E-R-L-L-P-Y-T-E-Q-C-V-L-A-I-D-M-A-A-G-E-M-K-V-E-W-D-A-D-F"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-G-S-P-C-H-F-A-L-F-E-L-K-P-E-F-Q-L-D-L-D-Q-L-A-T-R-Y-R-E-L-A-R-N-V-H-P-D-R-F-A-D-A-P-E-R-E-Q-R-L-A-L-E-R-S-A-S-L-N-E-A-Y-Q-T-L-K-S-P-P-K-R-A-R-Y-L-L-A-M-N-G-N-E-V-P-L-E-V-T-V-H-D-P-E-F-L-L-Q-Q-M-Q-L-R-E-D-L-E-D-L-Q-D-E-A-D-L-A-G-V-A-T-F-K-R-Q-L-K-V-A-Q-D-E-L-N-Q-S-F-A-A-C-W-N-D-A-A-Q-R-E-H-A-E-K-L-M-R-R-M-Q-F-L-D-K-L-S-H-E-V-R-Q-L-E-E-R-L-D-D"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-S-N-D-T-F-Y-L-K-R-E-K-R-F-L-V-L-L-G-I-I-C-L-S-L-I-G-G-A-L-Y-M-Q-I-A-L-G-E-A-P-C-P-L-C-I-L-Q-R-Y-A-L-L-F-I-A-I-F-A-F-I-G-A-A-M-N-G-R-R-G-V-T-V-F-E-A-L-V-T-L-S-A-L-C-G-I-A-A-A-G-R-H-A-W-I-L-A-H-P-S-D-S-C-G-I-D-I-L-Q-P-I-V-D-G-L-P-L-A-T-L-F-P-T-G-F-Q-V-S-G-F-C-T-T-P-Y-P-P-V-L-G-L-S-L-A-Q-W-A-L-T-A-F-V-L-T-A-I-L-V-P-A-C-I-I-R-N-R-R-K-P-Y"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-E-L-R-F-T-A-D-H-E-W-L-R-A-E-A-D-G-S-V-T-V-G-I-T-P-Y-A-Q-E-S-L-G-D-V-V-F-V-Q-L-P-E-L-Q-A-Y-A-Q-H-A-E-V-S-V-V-E-S-V-K-A-A-S-S-I-N-M-P-L-D-G-E-V-V-E-V-N-A-V-L-D-A-T-P-E-R-V-N-E-D-A-L-G-A-G-W-F-F-R-F-I-P-Q-D-A-Y-A-I-H-G-L-L-D-Q-D-A-Y-D-R-L-I-K-A-N-A-Q-A"} +{"text": "### FUNCTION Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing ### SEQUENCE -M-V-L-C-D-K-G-A-H-E-L-G-N-R-E-I-R-K-G-F-C-E-R-C-L-Y-P-E-Y-F-D-D-E-E-A-A-T-T-T-P-T-I-K-K-R-P-P-K-L-T-W-A-P-K-K-K-R-R-K-A-I-H-L-S-C-G-C-S-Y-Y-G-G-I-D-C-E-D-G-F-T-H-R-G-I-T-H-V-H-T-V-P-D-W-L-L-L-R-R-H-Q-E-P-N-L-L-P-P-P-E-H-N-N-N-G-D-G-E-Q-N-N-N-I-T-N-Q-S-Q-P-Q-P-A-E-S-V-G-S-P-D-L-L-A-E-L-G-G-T-F-S-I-T-S-S-E-W-R-S-I-I-R"} +{"text": "### FUNCTION Increases viral DNA accumulation Enhances infectivity and symptom expression ### SEQUENCE -M-D-S-R-T-G-E-L-L-T-Y-T-Q-C-Q-T-G-C-Y-F-D-D-I-K-N-P-I-Y-F-R-L-Q-N-T-T-T-M-A-T-G-N-K-I-I-T-L-Q-I-R-A-N-H-N-L-R-K-V-L-G-L-Q-I-C-W-L-N-L-V-V-L-S-V-S-P-R-L-S-G-E-A-L-L-D-R-F-K-F-H-V-M-K-H-L-N-N-L-G-V-I-S-I-N-N-V-I-R-S-I-N-H-F-I-D-L-F-D-Q-R-V-F-Y-A-P-S-F-Y-Y-N-I-K-M-R-L-Y"} +{"text": "### FUNCTION Pathogenicity determinant , a mechanism of plant viral defense that limits the accumulation of viral RNAs ### SEQUENCE -M-G-N-L-I-S-M-C-L-Y-N-S-K-G-N-S-T-A-K-I-N-D-S-S-T-W-Y-P-Q-P-G-Q-H-I-S-I-R-T-Y-R-E-L-N-P-A-P-T-S-T-P-T-S-T-R-T-E-T-L-S-N-G-E-N-S-R-L-T-L-D-L-L-E-E-A-S-R-Q-L-T-T-N-V-Q-R-P"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-A-I-Q-L-I-V-G-L-G-N-P-G-A-E-Y-E-Q-T-R-H-N-A-G-A-F-F-V-E-R-I-A-A-A-Q-R-V-N-L-V-P-E-R-K-F-F-G-L-T-G-R-F-T-H-Q-G-Q-D-V-R-L-L-I-P-T-T-Y-M-N-R-S-G-Q-A-V-A-A-L-A-G-F-Y-R-I-P-I-E-S-I-L-V-A-H-D-E-L-D-L-P-P-G-V-A-K-L-K-V-G-G-G-H-G-G-H-N-G-L-R-D-I-I-A-Q-L-G-N-Q-N-T-F-H-R-L-R-L-G-I-G-H-P-G-D-A-S-K-V-S-G-F-V-L-G-R-A-P-R-A-E-Q-E-K-L-D-A-S-I-D-F-A-L-G-V-L-P-D-I-F-A-G-E-W-N-R-A-M-K-N-L-H-S-Q-K-A"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-S-Q-P-M-T-V-Q-C-P-T-C-D-T-P-V-E-W-S-A-A-S-P-S-R-P-F-C-S-E-R-C-K-L-I-D-L-G-A-W-A-S-E-E-H-A-I-P-V-S-P-D-A-E-D-E-M-F-S-G-D-L-E-A-P-H-R-G-H"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-R-K-P-V-G-A-I-E-I-V-L-A-P-G-E-V-V-F-E-T-R-P-A-R-L-R-T-L-L-G-S-C-V-A-I-T-F-W-H-P-Q-Q-H-I-G-G-M-C-H-F-M-L-P-H-R-P-H-K-H-K-A-L-D-G-R-Y-G-D-E-A-L-E-M-L-I-R-H-A-L-A-N-H-T-K-P-R-D-Y-Q-V-K-L-F-G-G-G-Q-M-F-P-E-Q-Q-N-D-S-Q-Q-L-N-V-A-D-L-N-V-H-A-A-L-A-M-A-E-R-H-R-L-Q-L-K-A-Q-D-M-G-R-T-G-H-R-T-I-I-F-D-L-W-D-G-N-V-W-V-K-H-Q-P-I-E-V-T-E-K-D-A-R"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-N-I-T-N-P-N-Q-Y-Q-Y-F-A-A-V-W-A-E-P-I-P-M-L-N-Q-C-M-S-A-L-S-Q-S-Y-Q-T-Q-A-A-R-D-T-V-R-Q-Q-F-S-N-L-L-S-A-V-V-T-P-S-Q-R-F-P-D-T-G-S-R-V-Y-V-N-S-A-V-I-K-P-L-Y-E-A-L-M-K-S-F-D-T-R-N-R-I-I-E-T-E-E-E-S-R-P-S-A-S-E-V-A-N-A-T-Q-R-V-D-D-A-T-V-A-I-R-S-Q-I-Q-L-L-L-S-E-L-S-N-G-H-G-Y-M-N-R-A-E-F-E-A-L-L-P-W-T-T-A-P-A-T"} +{"text": "### FUNCTION Induces alteration of mitochondrial function that results in apoptosis contributing to tumor regression ### SEQUENCE -M-A-W-Y-H-Q-H-R-W-H-L-D-Y-S-I-P-R-Q-N-L-Q-A-F-L-T-T-I-T-F-I-D-P-Q-F-K-I-Q-E-N-G-L-T-E-G-E-Y-K-T-Q-I-V-K-Q-I-I-P-Q-L-C-R-I-P-N-Q-N-S-P-P-P-I-W-V-Q-G-P-R-I-K-G-D-P-T-W-L-K-I-N-A-K-F-I-T-E-L-I-P-K-Q-K-G-T-K-N-I-S-T-K-T-Y-L-S-R-L-F-V-I-W-L-Q-N"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-P-S-A-K-K-R-A-K-Q-A-E-K-R-R-S-H-N-A-S-L-R-S-M-V-R-T-Y-I-K-N-V-V-K-A-I-D-A-K-D-A-E-K-A-Q-A-A-Y-V-L-A-V-P-V-I-D-R-M-A-D-K-G-I-I-H-K-N-K-A-A-R-H-K-G-R-L-N-G-H-I-K-A-L-S-L-A-A-A-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-V-T-G-G-K-Q-Y-K-V-A-P-G-E-Y-L-K-I-E-K-L-E-I-A-T-G-E-S-V-T-F-D-R-V-L-L-V-G-N-G-D-D-V-N-I-G-A-P-V-V-A-G-A-T-V-V-A-E-V-I-S-Q-G-R-H-D-K-V-R-I-I-K-F-R-R-R-K-H-H-M-K-R-M-G-H-R-Q-W-Y-T-E-I-K-I-T-G-I-Q-A"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-R-K-K-A-A-L-D-F-E-Q-S-L-A-D-L-Q-A-L-V-E-R-L-E-N-G-E-L-S-L-E-D-S-L-T-A-F-E-Q-G-V-R-L-T-R-D-C-Q-S-A-L-T-Q-A-E-Q-K-V-Q-V-L-L-E-R-D-G-E-L-T-E-E-P-F-D-D-A-E-L-P-E"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-I-S-D-D-T-D-Q-F-N-P-R-D-A-K-S-P-E-I-A-K-G-K-S-A-K-R-R-E-A-R-Q-M-A-T-Q-A-L-Y-Q-R-H-M-A-G-H-A-L-N-E-I-E-A-Q-F-R-V-D-N-D-F-S-N-V-D-G-T-Y-F-R-E-L-L-H-G-V-A-I-N-Q-T-E-I-D-T-A-L-T-P-C-L-D-L-T-I-E-E-L-D-P-I-E-L-A-I-L-R-L-S-T-F-E-L-L-K-R-I-D-V-P-Y-R-V-V-I-N-E-G-I-E-L-A-K-V-Y-G-S-T-D-G-H-K-F-V-N-G-V-L-D-K-L-A-P-R-L-R-E-V-E-V-K-A-H-K-R"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-G-A-N-D-T-K-V-I-D-S-R-L-V-A-E-G-E-Q-V-R-R-R-R-E-C-L-A-C-G-E-R-F-T-T-F-E-T-A-E-L-V-L-P-R-L-I-K-Q-D-G-S-R-Q-P-F-D-E-E-K-L-R-A-G-M-Q-R-A-L-E-K-R-P-V-S-V-E-R-L-E-A-A-L-A-H-I-K-H-K-L-R-A-T-G-E-R-E-V-K-S-L-V-V-G-E-L-V-M-G-E-L-Q-K-L-D-E-V-A-Y-I-R-F-A-S-V-Y-R-R-F-Q-D-L-N-E-F-R-E-E-I-D-R-L-A-R-E-P-G-K-E"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-R-G-V-N-K-V-I-L-V-G-T-C-G-Q-D-P-E-V-R-Y-L-P-N-G-N-A-V-T-N-L-S-L-A-T-S-E-Q-W-T-D-K-Q-S-G-Q-K-V-E-K-T-E-W-H-R-V-S-M-F-G-K-V-A-E-I-A-G-E-Y-L-R-K-G-S-Q-V-Y-I-E-G-K-L-Q-T-R-E-W-E-K-D-G-I-K-R-Y-T-T-E-I-V-V-D-M-Q-G-T-M-Q-L-L-G-G-R-P-Q-G-D-A-Q-Q-G-Q-G-G-G-G-N-Y-N-Q-S-A-P-R-P-Q-Q-S-R-P-Q-Q-S-A-P-Q-Q-S-A-P-Q-Q-N-Y-N-Q-Q-P-P-Q-Q-R-D-S-R-P-A-P-Q-Q-Q-A-P-Q-P-A-A-D-F-D-S-F-D-D-D-I-P-F"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-P-A-A-R-P-R-K-K-V-K-K-T-V-V-D-G-I-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-S-W-A-T-S-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-R-A-G-Q-A-A-L-E-Y-G-L-K-N-L-D-V-N-V-K-G-P-G-P-G-R-E-S-A-V-R-A-L-N-G-C-G-Y-K-I-A-S-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-D-N-K-H-T-V-I-S-L-T-Y-I-Y-G-V-G-R-T-T-A-Q-K-I-C-A-T-T-G-V-N-P-A-V-K-I-K-D-L-S-D-E-Q-I-E-Q-L-R-G-E-V-A-K-F-T-T-E-G-D-L-R-R-E-I-N-M-K-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-R-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-D-L-S-P-A-P-G-S-R-R-E-K-H-R-P-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-S-S-R-S-G-G-T-I-A-P-G-F-E-G-G-Q-Q-P-L-H-R-R-L-P-K-F-G-F-V-S-L-K-A-M-D-R-A-E-V-R-L-S-E-L-A-K-V-E-G-D-I-V-T-V-Q-S-L-K-D-A-N-V-I-N-Q-N-V-Q-R-V-K-I-M-L-S-G-E-V-T-R-A-V-T-I-K-G-I-A-A-T-K-G-A-R-A-A-I-E-A-A-G-G-K-F-E-E"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-N-H-D-Q-K-R-D-E-G-Y-I-E-K-L-V-Q-V-N-R-V-A-K-T-V-K-G-G-R-I-F-T-F-T-A-L-T-V-V-G-D-G-K-G-R-V-G-F-G-R-G-K-S-R-E-V-P-A-A-I-Q-K-A-M-E-A-A-R-R-N-M-I-Q-V-D-L-N-G-T-T-L-Q-Y-A-M-K-S-A-H-G-A-S-K-V-Y-M-Q-P-A-S-E-G-T-G-I-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-Q-N-V-L-A-K-C-Y-G-S-T-N-P-V-N-V-V-H-A-T-F-K-G-L-K-G-M-Q-S-P-E-S-I-A-A-K-R-G-K-R-V-E-E-I-I"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-T-V-K-K-V-T-R-L-R-R-A-R-K-A-R-L-K-M-H-E-L-E-V-V-R-L-C-V-H-R-S-S-Q-H-I-Y-A-Q-V-I-S-A-D-G-S-K-V-L-A-S-A-S-T-L-D-K-E-L-R-D-G-A-T-G-N-I-D-A-A-T-K-V-G-K-L-V-A-E-R-A-K-A-A-G-V-S-Q-V-A-F-D-R-S-G-F-K-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-G-G-L-E-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-N-P-V-K-L-P-S-G-V-E-V-K-L-V-G-Q-Q-L-S-V-K-G-A-K-G-T-L-E-L-I-I-H-S-S-V-E-I-V-E-E-A-G-E-L-R-F-A-A-R-N-G-D-Q-Q-T-R-A-M-A-G-T-T-R-A-L-V-N-N-M-V-Q-G-V-S-Q-G-F-E-R-K-L-Q-L-V-G-V-G-Y-K-A-Q-A-K-G-T-V-L-N-L-A-L-G-F-S-H-P-V-D-Y-E-L-P-N-G-I-T-A-E-T-P-S-Q-T-D-I-L-I-R-G-I-D-K-Q-L-V-G-Q-V-A-A-E-I-R-D-F-R-R-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-V-V-R-R-K-E-A-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-L-A-D-M-L-T-R-I-R-N-A-Q-M-A-E-K-P-V-V-S-M-P-S-S-T-L-K-V-A-V-A-K-V-L-K-D-E-G-Y-I-A-G-Y-Q-I-S-S-E-V-K-S-S-L-S-I-E-L-K-Y-F-E-G-R-P-V-I-E-E-V-K-R-V-S-R-P-G-L-R-Q-Y-K-S-S-D-D-L-P-K-V-R-G-G-L-G-V-S-I-V-S-T-S-K-G-V-M-T-D-R-A-A-R-A-A-G-V-G-G-E-V-L-C-T-V-F"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-K-N-R-E-L-K-R-Q-L-T-V-A-K-Y-A-K-K-R-A-E-L-K-A-I-I-V-D-L-N-A-S-P-E-A-R-W-E-A-T-V-A-L-Q-K-Q-P-R-D-A-S-A-A-R-M-R-N-R-C-R-I-T-G-R-P-H-G-V-Y-R-K-F-G-L-G-R-N-K-L-R-E-A-A-M-R-G-D-V-P-G-L-V-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-R-L-K-E-I-Y-R-K-E-I-A-P-K-L-K-E-E-L-K-L-G-N-V-M-E-V-P-R-V-T-K-I-T-L-N-M-G-L-G-E-A-I-G-D-K-K-V-I-E-N-A-V-A-D-L-E-K-I-T-G-Q-K-V-V-V-T-Y-A-R-K-S-I-A-G-F-K-V-R-E-G-W-P-I-G-V-K-V-T-L-R-R-D-R-M-Y-E-F-L-D-R-L-L-S-I-S-L-P-R-V-R-D-F-R-G-L-N-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-K-E-Q-I-I-F-P-E-I-D-Y-D-K-I-D-A-L-R-G-L-D-I-T-L-T-T-T-A-K-N-D-D-E-G-R-A-L-L-R-A-F-K-F-P-F-R-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-K-I-R-R-D-D-E-I-I-V-I-A-G-K-D-K-G-K-R-G-K-V-L-K-V-L-A-D-D-R-L-V-V-G-G-I-N-L-V-K-R-H-T-K-P-N-P-M-S-G-V-Q-G-G-I-V-E-K-E-A-P-L-H-A-S-N-V-A-I-F-N-G-A-T-N-K-A-D-R-V-G-F-K-V-E-D-G-K-K-I-R-V-F-K-S-T-Q-K-A-V-D-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-T-Q-S-M-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-G-I-G-D-I-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-Q-V-M-T-A-V-V-V-R-T-R-H-G-V-R-R-A-D-G-S-I-I-R-F-D-G-N-A-A-V-L-L-N-N-K-Q-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-K-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-E-A-E-K-T-V-R-T-L-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-L-I-E-R-R-V-K-H-P-I-Y-G-K-Y-V-K-R-S-T-K-L-H-A-H-D-E-T-N-Q-C-H-I-G-D-K-V-T-I-R-E-T-R-P-V-A-K-T-K-S-W-A-L-V-D-I-L-E-R-A-V-E-V"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-Q-M-T-G-H-N-R-G-L-A-L-R-G-S-K-V-S-F-G-E-F-A-L-K-S-V-A-R-G-R-L-T-A-R-Q-I-E-S-A-R-R-A-L-T-R-H-V-K-R-G-G-K-I-W-I-R-V-F-P-D-K-P-V-T-K-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-K-V-L-Y-E-I-E-G-V-T-E-E-L-A-R-E-A-F-A-L-A-A-A-K-L-P-L-A-T-S-F-V-K-R-T-V-M"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-V-A-A-K-L-S-G-A-R-I-S-A-Q-K-A-R-L-V-A-D-Q-I-R-G-K-K-V-G-E-A-L-N-L-L-A-F-S-S-K-K-A-A-E-I-L-K-K-V-L-E-S-A-V-A-N-A-E-H-N-E-G-A-D-V-D-D-L-K-V-S-T-V-F-V-N-E-G-R-S-L-K-R-I-M-P-R-A-K-G-R-A-D-R-I-V-K-R-S-C-H-I-T-V-K-V-A-D-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-I-E-V-A-A-E-K-N-D-R-K-P-V-K-T-W-S-R-R-S-M-I-L-P-Q-M-V-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-L-V-S-E-D-M-V-G-H-K-L-G-E-F-A-G-T-R-T-Y-R-G-H-V-A-D-K-K-A-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-Q-E-R-V-F-K-V-L-L-G-P-H-V-S-E-K-A-T-V-L-A-D-K-K-G-Q-F-V-F-K-V-A-T-D-A-T-K-L-E-I-K-K-A-V-E-S-L-F-S-V-K-V-E-R-V-T-T-L-N-V-L-G-K-S-K-R-T-A-R-G-L-G-K-R-N-D-W-K-K-A-V-I-S-L-Q-P-G-Q-D-L-D-F-S-S-S-A-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA It is important during the early stages of 50S assembly It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-Q-L-N-V-N-D-A-Q-A-I-E-V-S-E-L-T-F-G-G-E-F-N-E-T-L-V-H-Q-A-V-V-A-Y-M-A-G-G-R-Q-G-S-K-Q-Q-K-T-R-S-D-V-R-G-G-G-K-R-P-W-R-Q-K-G-T-G-R-A-R-A-G-T-I-R-S-P-I-W-R-G-G-G-T-T-F-A-A-R-P-Q-D-H-T-Q-K-L-N-K-K-M-Y-R-A-A-L-R-S-I-L-A-E-L-V-R-T-D-R-L-V-V-V-Q-D-F-A-V-E-A-P-K-T-K-D-L-L-N-K-L-T-G-M-G-L-T-D-V-L-I-V-S-D-A-V-D-Q-N-L-Y-L-A-A-R-N-L-P-H-V-D-V-R-D-V-Q-G-S-D-P-V-S-L-I-A-Y-D-K-V-L-I-T-V-S-A-V-K-K-F-E-E-L-L-G"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-Q-I-R-I-R-L-K-A-F-D-H-R-L-I-D-Q-S-T-Q-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-R-F-T-V-L-V-S-P-H-V-N-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-V-L-D-I-V-Q-P-T-E-K-T-V-D-A-L-M-K-L-D-L-A-A-G-V-E-V-Q-I-S-L-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-A-A-K-R-E-V-L-D-D-P-K-Y-G-S-Q-I-L-A-K-F-M-N-H-V-M-E-S-G-K-K-A-V-A-E-R-I-V-Y-G-A-L-E-K-V-K-E-R-K-N-S-D-P-L-E-I-F-E-K-A-L-D-A-I-A-P-L-V-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-P-S-R-R-N-A-L-A-M-R-W-L-V-D-F-A-R-K-R-G-E-K-S-M-A-L-R-L-A-G-E-L-M-D-A-A-E-G-K-G-A-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-S-H-Y-R-F"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-N-Q-L-V-R-Q-P-R-K-R-I-V-E-K-S-D-V-P-A-L-Q-N-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-S-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-S-L-D-T-S-G-V-K-G-R-N-Q-G-R-S-K-Y-G-T-K-K-P-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-I-S-Q-D-D-I-L-N-A-V-A-E-M-S-V-I-Q-V-V-E-L-I-K-A-F-E-E-K-F-G-V-T-A-A-A-G-S-A-G-P-A-A-A-A-A-V-V-E-E-Q-T-E-F-N-V-M-L-L-E-A-G-E-K-K-V-N-V-I-K-A-V-R-E-L-T-G-L-G-L-K-E-A-K-A-V-V-D-G-A-P-G-I-V-L-E-A-V-A-K-D-A-A-D-K-A-K-A-T-L-E-E-A-G-A-K-V-E-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-I-K-L-E-D-K-K-A-I-V-A-E-V-N-E-A-A-K-A-G-L-S-A-V-V-A-D-A-R-G-V-T-V-G-A-M-T-G-L-R-K-E-A-R-E-A-G-V-Y-V-R-V-V-R-N-T-L-L-K-R-A-V-A-D-T-E-F-S-V-L-N-D-V-F-T-G-P-T-L-I-A-F-S-N-E-H-P-G-A-A-A-R-L-F-K-E-F-A-K-G-Q-D-K-F-E-I-K-A-A-A-F-E-G-K-F-L-A-A-N-Q-I-D-V-L-A-T-L-P-T-R-N-E-A-I-S-Q-L-M-S-V-I-Q-G-A-T-S-K-L-A-R-T-L-A-A-V-R-D-Q-K-E-A-A-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-T-A-Y-I-K-L-Q-V-K-A-A-Q-A-N-P-S-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-F-N-A-R-T-Q-G-I-E-P-G-L-P-T-P-V-I-I-T-V-Y-S-D-R-S-F-T-F-E-T-K-S-T-P-A-S-V-L-L-K-K-A-A-G-L-T-S-G-S-A-R-P-N-T-V-K-V-G-T-V-T-R-A-Q-L-E-D-I-A-K-A-K-N-A-D-L-T-A-A-D-M-E-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-N-V-E-G-V"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-V-E-S-F-T-P-T-A-L-E-F-T-P-N-A-A-H-K-V-K-T-L-V-D-E-E-G-N-D-R-L-K-L-R-V-F-V-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-D-V-A-D-D-D-T-I-V-E-R-E-G-V-S-L-V-V-D-P-M-S-F-Q-Y-L-A-G-A-E-V-D-Y-Q-E-G-L-E-G-S-R-F-V-I-K-N-P-N-A-S-T-T-C-G-C-G-S-S-F-S-I"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-T-E-F-K-R-I-P-P-E-Q-A-Q-A-L-R-A-Q-G-A-V-L-V-D-V-R-D-A-Q-A-F-Q-S-N-H-I-P-D-S-Q-H-L-D-N-H-S-I-A-D-F-I-A-N-A-D-L-D-K-P-L-V-V-V-C-Y-H-G-N-S-S-Q-S-A-A-A-Y-L-V-G-Q-G-F-S-D-V-Y-S-V-D-G-G-F-E-R-W-R-S-T-F-P-E-E-T-A-Q-G"} +{"text": "### FUNCTION Required for coenzyme pyrroloquinoline quinone ### SEQUENCE -M-S-W-T-K-P-A-Y-T-D-L-R-I-G-F-E-V-T-M-Y-F-A-S-R"} +{"text": "### FUNCTION Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone biosynthetic pathway ### SEQUENCE -M-K-H-E-I-K-H-D-P-A-F-R-A-L-T-P-K-W-H-H-G-Y-R-F-Q-Y-E-P-A-Q-K-A-H-V-V-L-Y-P-E-G-M-I-K-L-N-D-S-A-S-L-I-G-G-L-I-D-G-E-R-T-I-A-A-I-I-A-E-L-Q-R-E-F-P-N-I-P-E-L-G-M-D-V-D-D-F-M-K-V-A-K-E-K-Y-W-I-D-L-V"} +{"text": "### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-V-G-M-Q-P-I-R-R-Q-Q-L-I-Q-A-T-L-T-A-V-D-Q-V-G-M-G-D-A-S-I-A-L-I-A-R-L-A-G-V-S-N-G-I-I-S-H-Y-F-Q-D-K-N-G-L-I-A-A-T-M-R-H-L-M-N-A-L-I-Q-N-V-R-E-R-R-Q-A-L-T-E-D-S-P-R-A-H-L-Q-V-I-I-E-G-N-F-D-A-S-Q-V-S-G-P-A-M-K-T-W-L-A-F-W-A-T-S-M-H-H-P-S-L-H-R-L-Q-R-I-N-D-H-R-L-Y-S-N-L-C-C-Q-F-R-R-T-L-P-L-E-Q-A-R-N-A-A-R-G-L-A-A-L-I-D-G-L-W-L-R-G-A-L-S-G-D-A-F-D-T-E-Q-A-Q-R-I-A-Y-E-Y-M-D-F-Q-L-A-K-S-A-S"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-I-P-A-E-L-R-F-A-E-S-H-E-W-A-R-L-E-A-D-G-T-V-T-V-G-I-S-D-H-A-Q-E-A-L-G-D-V-V-F-V-E-L-P-E-I-G-K-V-F-A-A-G-D-V-A-G-V-V-E-S-V-K-A-A-S-D-I-Y-S-P-V-A-G-E-V-V-E-V-N-E-A-L-G-D-S-P-E-S-L-N-S-E-P-Y-S-A-W-I-F-K-V-K-P-A-S-A-E-A-D-L-A-K-L-L-D-A-A-G-Y-K-G-A-I-G-E"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-S-L-T-E-A-R-F-H-D-L-V-D-A-T-Q-Q-N-I-E-D-V-F-D-E-S-G-L-D-V-D-L-E-N-S-A-G-V-L-T-V-K-F-E-G-G-S-Q-L-I-F-S-R-Q-E-P-L-R-Q-L-W-L-A-A-K-S-G-G-F-H-F-D-Y-D-E-E-E-S-R-W-A-C-D-T-S-D-E-L-L-S-E-M-L-A-R-M-T-F-E-Q-A-G-A-D-L-D-F-S-E-I"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-I-L-N-I-L-E-F-P-D-S-R-L-R-T-L-A-K-P-V-A-M-V-D-D-G-I-R-Q-L-V-D-D-M-F-E-T-M-Y-E-A-P-G-I-G-L-A-A-T-Q-V-N-V-H-K-R-V-V-V-M-D-L-S-E-D-R-S-A-P-M-V-F-I-N-P-E-I-E-K-L-T-D-E-M-D-Q-Y-Q-E-G-C-L-S-V-P-G-F-Y-E-N-V-D-R-P-Q-K-V-R-V-K-A-L-D-R-D-G-K-P-Y-E-L-V-A-E-G-L-L-A-I-C-I-Q-H-E-C-D-H-L-N-G-K-L-F-V-D-Y-L-S-N-L-K-R-D-R-I-K-K-K-L-E-K-Q-H-K-L-N-A"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-C-L-E-H-V-D-N-R-F-E-L-V-M-L-S-T-K-R-A-R-Q-L-A-T-G-G-K-E-P-K-L-A-W-E-N-D-K-P-T-V-M-A-L-R-E-I-A-A-G-L-M-D-Y-A-V-I-A-E-A-E-I-V-E-D-E-P-L-F-A-A-F-E-D-E-S-N-E-A-V"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-I-N-A-T-L-I-G-Q-S-V-A-F-L-I-F-V-L-F-C-M-K-Y-V-W-P-P-V-I-T-A-L-Q-E-R-Q-K-K-I-A-D-G-L-D-A-A-N-R-A-A-R-D-L-E-L-A-Q-E-K-A-G-Q-Q-L-R-E-A-K-A-Q-A-A-E-I-I-E-Q-S-K-K-R-A-A-Q-L-V-D-E-A-R-E-Q-A-R-V-E-A-D-R-V-K-A-Q-A-L-A-E-I-E-Q-E-L-N-S-A-K-D-A-L-R-A-Q-V-G-A-L-A-V-G-G-A-E-K-I-L-G-A-T-I-D-Q-N-A-H-A-E-L-V-N-K-L-A-A-E-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-L-T-T-L-A-R-P-Y-A-K-A-A-F-E-H-A-Q-A-H-Q-Q-L-A-N-W-S-A-M-L-G-L-A-A-A-V-S-Q-D-D-T-M-Q-R-L-L-K-A-P-R-L-T-S-A-E-K-A-A-T-F-I-D-V-C-G-D-K-F-N-A-Q-A-Q-N-F-I-H-V-A-A-E-N-D-R-L-L-L-L-P-E-I-A-A-L-F-D-L-Y-K-A-E-Q-E-K-S-V-D-V-E-V-T-S-A-F-A-L-N-Q-E-Q-Q-D-K-L-A-K-V-L-S-A-R-L-G-Q-E-V-R-L-H-A-S-E-D-A-S-L-I-G-G-V-V-I-R-A-G-D-L-V-I-D-G-S-V-R-G-K-I-A-K-L-A-E-A-L-K-S"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-M-T-V-H-C-D-I-V-S-A-E-G-E-I-F-S-G-L-V-E-M-V-V-A-H-G-N-L-G-D-L-G-I-A-P-G-H-A-P-L-I-T-N-L-K-P-G-P-I-T-L-T-K-Q-G-G-A-H-E-V-F-Y-I-S-G-G-F-L-E-V-Q-P-N-M-V-K-V-L-A-D-T-V-Q-R-A-A-D-L-D-E-A-Q-A-Q-E-A-L-K-A-A-E-N-A-L-N-L-K-G-A-D-F-D-Y-G-A-A-A-A-R-L-A-E-A-A-A-Q-L-R-T-V-Q-Q-M-R-K-G-K"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-S-Y-E-S-P-Q-A-A-A-V-A-W-L-P-Y-S-Q-L-A-T-D-I-D-Q-P-T-L-D-W-L-F-D-E-G-S-L-T-R-R-L-T-R-L-S-I-D-H-F-S-V-T-P-L-F-E-G-W-Q-P-L-R-D-D-E-C-Q-A-L-G-I-A-A-G-A-E-G-W-V-R-E-V-Y-L-R-G-H-G-Q-P-W-V-F-A-R-S-V-A-S-R-S-A-L-E-R-G-G-L-D-L-E-T-L-G-S-R-S-L-G-E-L-L-F-C-D-Q-A-F-I-R-H-P-L-E-V-C-T-Y-P-Q-A-W-L-P-S-E-A-A-H-A-A-L-W-G-R-R-S-R-F-E-R-N-G-L-D-L-L-V-A-E-V-F-L-P-A-L-W-Q-A-A-K-E-E-N-R"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-C-L-E-H-V-D-N-R-F-E-L-V-M-L-S-T-K-R-A-R-Q-L-A-T-G-G-K-E-P-R-V-A-W-E-N-D-K-P-T-V-V-A-L-R-E-I-A-E-G-I-V-T-N-E-F-I-A-A-E-E-I-V-T-E-D-P-V-F-A-A-F-E-D-E-N-N-E-A-V"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-H-A-L-Q-A-K-I-L-D-P-R-L-G-S-E-F-P-L-P-A-Y-A-T-P-G-S-A-G-L-D-L-R-A-L-L-K-E-D-T-I-L-E-P-G-Q-T-V-L-I-P-T-G-L-S-I-Y-I-G-D-P-G-L-A-A-V-I-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-E-L-M-V-S-C-W-N-R-G-N-T-P-F-T-I-A-V-G-E-R-I-A-Q-L-V-L-V-P-V-V-Q-A-H-F-E-I-V-E-A-F-D-E-S-Q-R-G-A-G-G-F-G-H-S-G-S-H"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-S-L-S-E-A-R-F-H-D-L-V-D-A-T-Q-Q-A-L-E-D-L-F-D-E-S-G-L-D-L-D-M-E-N-S-A-G-V-L-T-V-K-F-E-G-G-A-Q-L-I-F-S-R-Q-E-P-L-R-Q-L-W-L-A-D-R-S-G-G-F-H-F-D-Y-D-E-D-S-G-K-W-V-C-E-K-S-E-E-L-L-G-E-M-L-E-R-I-V-W-E-R-A-G-E-K-L-D-F-D-E-I"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-I-P-A-E-L-R-F-A-E-S-H-E-W-A-R-L-E-A-D-G-S-V-T-V-G-I-S-D-H-A-Q-E-A-L-G-D-V-V-F-V-E-L-A-E-V-G-K-V-F-G-A-G-D-A-A-G-V-V-E-S-V-K-A-A-S-D-I-Y-A-P-V-G-G-E-V-I-A-V-N-E-E-L-A-D-S-P-E-L-L-N-E-E-P-Y-G-S-W-I-F-K-L-K-P-S-N-P-A-E-L-D-K-L-L-D-A-A-G-Y-Q-A-L-I-G-E"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-P-D-G-F-R-P-N-V-G-I-I-L-T-N-D-A-G-Q-V-L-W-A-R-R-I-N-Q-D-A-W-Q-F-P-Q-G-G-I-N-P-D-E-T-P-E-D-A-L-Y-R-E-L-N-E-E-V-G-L-E-R-D-D-V-E-I-L-A-C-T-R-G-W-L-R-Y-R-L-P-Q-R-L-V-R-T-H-S-Q-P-L-C-I-G-Q-K-Q-K-W-F-L-L-R-L-V-S-N-E-Q-R-V-R-M-D-L-T-G-K-P-E-F-D-G-W-R-W-V-S-Y-W-Y-P-L-G-Q-V-V-T-F-K-R-E-V-Y-R-R-A-L-K-E-L-A-P-R-L-L-T-R-D"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-T-D-Q-Q-T-N-G-A-A-A-E-D-N-S-P-Q-F-S-L-Q-R-I-Y-V-R-D-L-S-F-E-A-P-K-S-P-Q-I-F-R-Q-T-W-E-P-S-V-A-L-D-L-N-T-K-Q-K-S-L-E-G-D-F-H-E-V-V-L-T-L-S-V-T-V-K-N-G-D-E-V-A-F-I-A-E-V-Q-Q-A-G-I-F-L-I-A-N-L-D-A-P-S-M-S-H-T-L-G-A-F-C-P-N-I-L-F-P-Y-A-R-E-A-L-D-S-L-V-T-R-G-S-F-P-A-L-M-L-S-P-V-N-F-D-A-L-Y-A-Q-E-M-Q-R-M-Q-E-A-G-E-A-P-T-V-Q"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-D-L-R-L-L-L-G-F-D-Y-G-S-K-Q-I-G-V-A-V-G-Q-V-I-T-G-Q-A-R-E-L-C-T-L-K-A-Q-N-G-V-P-D-W-A-Q-V-E-K-L-I-A-E-W-K-P-D-A-I-V-V-G-L-P-L-N-M-D-G-T-P-S-E-M-S-A-R-A-E-K-F-A-R-R-L-N-G-R-F-N-L-P-V-H-T-H-D-E-R-L-T-T-F-E-A-K-G-E-R-M-A-R-G-G-Q-R-G-S-Y-R-D-N-P-V-D-A-I-A-A-A-L-L-L-Q-G-W-L-E-A-N-T"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-Q-N-P-Q-N-L-I-W-I-D-L-E-M-T-G-L-D-P-D-S-D-V-I-I-E-M-A-T-I-V-T-D-S-E-L-N-T-L-A-E-G-P-V-I-A-I-H-H-S-D-E-V-L-A-R-M-D-E-W-N-T-R-T-H-G-A-S-G-L-T-Q-R-V-R-E-S-K-V-S-M-A-E-A-E-A-Q-T-I-A-F-L-E-Q-W-V-P-K-G-K-S-P-I-C-G-N-S-I-C-Q-D-R-R-F-L-Y-R-H-M-R-N-L-E-N-Y-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-A-A-R-W-A-P-D-V-R-D-S-F-K-K-G-N-T-H-L-A-L-D-D-I-R-E-S-I-A-E-L-R-H-Y-R-E-H-F-I-K-L"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-S-K-G-H-S-L-Q-D-P-Y-L-N-T-L-R-K-E-K-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-S-I-E-S-F-D-Q-F-V-V-L-L-K-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-P-V-R-L-P-S-P-T-D-S-E-H-G-D-S-E-P-G-N-A"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-I-F-L-V-H-P-D-Q-S-E-Q-V-G-G-M-V-E-R-Y-T-K-L-I-E-E-D-G-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-A-I-N-N-V-H-K-A-H-Y-V-M-L-N-V-E-C-T-G-K-A-L-A-E-L-E-D-N-F-R-Y-N-D-A-V-I-R-N-L-V-I-R-R-D-E-A-V-T-G-Q-S-E-M-L-K-A-E-E-N-R-S-E-R-R-E-R-R-E-R-P-E-H-A-D-S-A-E-G-D-D-S-N-D-S-D-S-S-D-N-A-D-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-F-F-R-R-R-K-F-C-R-F-T-A-E-D-V-K-E-I-D-F-K-D-L-N-T-L-K-A-Y-V-S-E-T-G-K-I-V-P-S-R-I-T-G-T-K-A-R-Y-Q-R-Q-L-A-T-A-I-K-R-A-R-F-L-A-L-L-P-Y-T-D-S-H-G-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-L-I-L-L-E-K-V-A-N-L-G-N-L-G-D-K-V-K-V-K-A-G-Y-G-R-N-F-L-L-P-F-G-K-A-T-V-A-N-A-A-N-L-A-A-F-E-E-R-R-A-E-L-E-K-A-A-A-D-K-K-A-S-A-E-S-R-A-A-Q-L-A-E-L-E-V-T-I-T-A-T-A-G-D-E-G-K-L-F-G-S-I-G-T-H-D-I-A-D-A-L-T-A-S-G-V-E-V-A-K-A-E-V-R-L-P-N-G-T-I-R-Q-V-G-E-Y-D-V-A-V-H-L-H-S-D-V-E-A-T-V-R-V-V-V-V-A-A"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-L-E-L-D-I-Q-R-A-T-D-A-A-T-P-E-D-A-A-L-R-R-W-C-E-L-A-L-R-Q-R-S-A-D-S-E-M-T-I-R-L-V-D-E-A-E-G-R-E-L-N-H-T-Y-R-H-K-D-Y-A-T-N-V-L-S-F-P-A-D-V-P-D-D-L-L-D-I-P-L-L-G-D-L-V-I-C-V-A-V-V-E-R-E-A-A-E-Q-G-K-S-L-E-A-H-W-A-H-L-V-I-H-G-C-L-H-L-L-G-Y-D-H-I-E-D-E-E-A-E-E-M-E-S-L-E-R-E-L-L-A-E-L-G-H-P-D-P-Y-A-D-D-E-T-D-T-I-T-H"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-Q-K-K-H-P-T-G-T-I-A-Q-N-K-K-A-R-H-D-Y-F-I-E-H-K-F-E-A-G-L-V-L-S-G-W-E-V-K-S-L-R-A-G-K-A-H-L-T-D-S-Y-V-L-L-K-D-G-E-A-W-L-F-G-S-H-I-T-P-L-T-T-A-S-T-H-V-I-A-D-P-T-R-T-R-K-L-L-L-N-K-R-E-L-E-R-V-E-A-A-V-A-Q-K-G-Y-T-C-V-A-L-A-L-Y-W-S-K-H-L-I-K-C-E-I-A-L-G-K-G-K-K-E-F-D-K-R-D-T-M-R-E-R-D-S-N-R-E-L-Q-R-A-V-R-N-K-G-K-E-E"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-D-E-Q-L-N-E-K-D-L-N-V-E-E-T-G-A-G-N-A-A-D-T-R-V-L-E-L-E-E-Q-L-A-A-A-K-D-Q-A-L-R-A-V-A-D-L-Q-N-V-R-R-R-A-E-Q-D-V-E-K-A-H-K-F-A-L-E-K-F-S-S-D-L-L-P-V-I-D-S-L-E-L-A-L-A-H-S-S-A-D-D-E-H-V-K-Q-I-R-E-G-V-E-L-T-L-K-M-F-Q-D-T-L-K-R-Y-N-L-E-A-V-D-P-H-G-Q-P-F-N-P-E-H-H-Q-A-M-A-M-Q-E-N-A-E-V-E-P-N-S-V-L-N-V-F-Q-K-G-Y-L-L-N-G-R-L-L-R-P-A-M-V-V-V-S-K-A-P-S-A-A-Q-P-S-I-N-E-K-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-I-T-K-Y-P-M-T-V-Q-G-A-R-A-L-E-E-E-H-L-F-L-S-K-T-E-R-P-R-L-S-Q-A-I-G-E-A-R-E-L-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-E-Q-G-M-V-E-A-R-I-R-D-I-E-G-R-L-Q-N-S-V-V-I-D-V-T-T-I-P-H-T-G-K-V-I-F-G-T-T-V-V-L-A-N-T-E-T-D-E-E-V-T-Y-Q-I-V-G-E-D-E-A-D-V-K-Q-G-K-L-S-S-G-A-P-I-A-R-A-I-I-G-K-E-E-G-D-T-V-V-V-K-T-P-S-G-T-V-E-Y-E-I-V-E-V-K-H-I"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-H-E-G-V-Q-V-S-S-K-L-E-Q-L-Q-A-L-L-A-P-V-V-E-G-L-G-Y-Q-C-W-G-I-E-Y-V-S-Q-G-K-H-S-V-L-R-I-Y-I-D-K-E-G-G-I-L-V-D-D-C-E-A-V-S-R-Q-A-S-A-I-L-D-V-E-D-P-I-S-S-E-Y-T-L-E-V-S-S-P-G-M-D-R-P-L-F-T-L-E-Q-F-A-S-H-A-G-E-Q-V-K-I-K-L-R-S-P-F-E-G-R-R-N-F-Q-G-L-L-R-G-V-E-E-Q-D-V-V-V-Q-V-D-N-Q-E-F-L-L-P-I-D-S-I-D-K-A-N-I-I-P-S-F-D"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-E-Y-S-R-T-Q-R-I-G-D-Q-M-Q-R-E-L-A-E-L-I-R-R-E-V-K-D-P-R-V-G-L-V-T-I-T-A-V-D-V-S-R-D-L-G-H-A-K-V-F-I-T-V-M-G-E-E-T-P-D-A-V-Q-Q-S-L-K-A-L-N-S-A-A-S-F-L-R-L-H-L-G-R-S-M-Q-L-R-S-V-P-Q-L-H-F-H-F-D-E-S-V-S-R-G-V-H-L-S-A-L-I-E-R-A-V-A-E-D-R-L-H-K-D-A-D-E-S-D-T-K-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-S-V-E-E-K-A-Q-I-V-A-E-Y-Q-Q-A-A-G-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-N-I-N-K-L-Q-G-H-F-K-A-N-D-K-D-H-H-S-R-R-G-L-I-R-M-V-N-Q-R-R-K-L-L-D-Y-L-K-G-K-D-T-T-R-Y-S-A-L-I-G-R-L-G-L-R-R"} +{"text": "### FUNCTION Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues , using respiratory chain electrons Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain ### SEQUENCE -M-R-Y-P-W-F-R-L-A-I-F-I-V-G-C-L-F-P-V-W-W-L-Y-E-A-A-M-N-L-L-G-P-D-P-G-K-I-M-M-D-R-L-G-L-G-A-L-T-F-L-L-V-T-L-S-M-T-P-L-Q-K-L-T-G-W-S-G-W-I-V-V-R-R-Q-L-G-L-W-V-F-A-Y-I-V-L-H-I-L-C-Y-L-F-F-I-L-G-L-D-W-G-Q-L-A-V-E-L-R-K-R-P-Y-I-I-V-G-A-L-G-F-L-G-L-L-V-L-A-V-T-S-N-R-Y-S-Q-R-R-L-G-A-R-W-K-K-L-H-R-L-V-Y-A-V-L-G-L-G-L-L-H-F-L-W-I-V-R-S-D-L-R-E-W-A-I-Y-A-F-I-G-A-V-L-M-V-L-R-I-P-A-V-A-R-A-L-P-K-V-A-R"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-G-M-L-N-E-F-K-A-F-A-V-K-G-N-V-V-D-M-A-V-G-I-I-I-G-A-A-F-G-K-I-V-S-S-F-V-G-D-V-I-M-P-P-L-G-L-L-I-G-G-V-D-F-S-D-L-A-I-T-L-K-A-A-E-G-D-V-P-A-V-V-L-A-Y-G-K-F-I-Q-T-V-I-D-F-V-I-V-A-F-A-I-F-M-G-V-K-A-I-N-K-L-K-R-E-E-A-V-A-P-T-T-P-P-V-P-S-A-E-E-T-L-L-T-E-I-R-D-L-L-K-T-Q-N-Q-N-R-L-P"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-R-D-I-L-K-M-G-D-E-R-L-L-R-I-A-P-P-V-P-E-H-M-L-G-S-A-E-L-Q-Q-L-I-D-D-M-F-E-T-M-R-H-V-G-G-V-G-L-A-A-P-Q-V-G-I-D-L-Q-L-V-I-F-G-F-E-R-S-E-R-Y-P-D-A-E-A-V-P-Q-T-I-L-L-N-P-V-I-T-P-T-S-S-E-V-E-D-G-W-E-G-C-L-S-V-P-G-L-R-G-V-V-P-R-F-K-H-I-C-Y-Q-G-I-D-P-Q-G-S-P-I-N-R-F-A-D-G-F-H-A-R-V-V-Q-H-E-C-D-H-L-I-G-R-L-Y-P-S-R-I-Q-D-F-A-K-F-G-Y-T-E-V-L-F-P-G-L-E-V-S-E-D"} +{"text": "### FUNCTION Involved in tetrahydrobiopterin biosynthesis Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 May also have a positive regulatory role in the expression of phhA ### SEQUENCE -M-N-A-L-N-Q-A-H-C-E-A-C-R-A-D-A-P-K-V-T-D-E-E-L-A-E-L-I-R-E-I-P-D-W-N-I-E-V-R-D-G-H-M-E-L-E-R-V-F-L-F-K-N-F-K-H-A-L-A-F-T-N-A-V-G-E-I-A-E-A-E-G-H-H-P-G-L-L-T-E-W-G-K-V-T-V-T-W-W-S-H-S-I-K-G-L-H-R-N-D-F-I-M-C-A-R-T-D-K-V-A-E-T-A-E-G-R-K"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-K-G-G-M-A-G-L-M-K-Q-A-Q-Q-M-Q-E-K-M-Q-K-M-Q-E-E-L-A-N-A-E-V-T-G-Q-S-G-G-G-L-V-S-V-V-M-T-G-R-H-D-V-K-R-V-S-I-D-Q-S-L-M-S-T-D-E-D-D-K-E-V-L-E-D-L-I-A-A-A-L-N-D-A-V-R-K-V-E-Q-S-S-Q-E-K-M-G-G-M-T-A-G-M-Q-L-P-P-G-F-K-M-P-F"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-F-S-P-L-I-R-Q-L-I-D-G-L-R-I-L-P-G-V-G-Q-K-T-A-Q-R-M-A-L-Q-L-L-E-R-D-R-S-G-G-L-R-L-A-Q-A-L-T-Q-A-M-E-G-V-G-H-C-R-Q-C-R-T-L-T-E-Q-E-L-C-P-Q-C-A-D-P-R-R-D-D-T-Q-L-C-V-V-E-G-P-T-D-V-Y-A-V-E-Q-T-G-Y-R-G-R-Y-F-V-L-K-G-H-L-S-P-L-D-G-L-G-P-E-A-I-G-I-P-Q-L-M-A-R-I-E-E-Q-G-T-F-T-E-V-I-L-A-T-N-P-T-V-E-G-E-A-T-A-H-Y-I-A-Q-L-L-S-E-K-G-L-V-A-S-R-I-A-H-G-V-P-L-G-G-E-L-E-M-V-D-G-G-T-L-A-H-A-F-A-G-R-R-P-I-S-L"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-H-S-D-A-F-D-L-K-A-L-I-R-P-V-V-D-F-P-K-P-G-V-I-F-R-D-I-T-P-L-F-Q-S-P-R-G-L-R-Y-V-A-D-Q-F-I-E-R-Y-V-E-A-E-F-S-H-I-G-A-M-D-A-R-G-F-L-I-G-S-I-I-A-H-Q-L-N-K-P-L-I-L-F-R-K-Q-G-K-L-P-A-D-V-L-S-E-G-Y-Q-T-E-Y-G-E-A-F-L-E-V-H-A-D-S-L-C-E-G-D-S-V-L-I-F-D-D-L-I-A-T-G-G-T-L-L-A-A-A-N-L-V-R-R-T-G-A-Q-V-F-E-A-A-A-I-I-D-L-P-E-L-D-G-S-R-R-L-Q-A-A-G-V-P-T-F-C-L-T-E-F-S-L-S-E-Y"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-T-A-Y-L-R-P-A-L-S-L-A-L-L-M-T-L-V-T-G-A-L-Y-P-L-A-V-T-G-I-A-Q-V-A-F-P-N-Q-A-N-G-S-L-V-R-D-A-Q-G-Q-V-R-G-S-A-L-I-A-Q-D-F-Q-G-D-G-W-F-H-S-R-P-S-A-G-A-Y-A-T-V-A-S-G-A-S-N-L-S-P-S-N-P-A-L-A-E-R-V-K-G-D-A-A-T-L-Y-Q-A-Q-Q-G-P-V-P-Q-A-L-L-T-T-S-G-S-G-L-D-P-H-L-P-P-E-A-L-A-Y-Q-I-P-R-V-A-A-A-R-Q-L-P-V-E-R-L-Q-A-L-L-E-Q-A-T-L-H-P-L-I-G-P-P-V-V-N-V-L-A-L-N-Q-A-L-E-K-L-A-I-V-R"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-H-A-P-S-E-I-R-L-T-F-N-Q-D-R-P-Q-S-N-E-D-D-G-S-G-L-A-V-Q-E-A-K-P-I-L-Q-A-P-P-M-Y-K-V-V-L-F-N-D-D-Y-T-P-M-D-F-V-V-E-V-L-E-T-F-F-S-L-N-R-E-L-A-T-K-I-M-L-T-V-H-T-E-G-R-A-V-C-G-L-F-T-R-D-I-A-E-T-K-A-M-Q-V-N-Q-Y-A-R-E-S-Q-H-P-L-L-C-E-I-E-K-D-G"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-A-L-I-A-A-V-S-A-G-G-I-A-G-T-L-L-R-F-A-T-T-N-W-V-A-A-H-W-P-R-H-F-Y-A-G-T-L-A-V-N-L-V-G-C-L-L-I-G-L-L-Y-G-L-F-L-H-K-P-L-A-P-V-E-L-R-A-G-L-I-V-G-F-L-G-G-L-T-T-F-S-S-F-S-L-D-T-V-R-L-M-E-S-G-Q-V-P-L-A-L-G-Y-T-S-I-S-V-V-G-G-L-L-A-T-W-A-G-L-S-L-T-R-F"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-K-V-G-E-S-I-V-I-N-D-D-I-K-V-T-I-L-G-V-K-G-M-Q-V-R-I-G-I-D-A-P-K-D-V-Q-V-H-R-E-E-I-F-K-R-I-Q-A-G-S-P-A-P-E-K-H-E-D-T-H"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-Q-R-I-T-I-T-L-D-E-E-L-L-D-V-I-D-R-R-V-A-T-Q-G-Y-Q-G-R-S-E-A-I-R-D-L-L-R-A-G-M-R-E-S-E-A-L-P-D-D-A-A-C-V-A-V-V-S-Y-L-Y-D-H-S-T-R-E-L-P-R-R-L-N-Q-T-L-H-A-H-H-D-L-T-R-S-T-L-H-V-H-L-D-A-G-H-C-L-E-V-S-V-L-Q-G-E-S-G-R-I-G-E-L-S-R-Q-L-M-V-E-R-G-V-E-H-G-Q-V-Q-V-I-P-A-P-G-Q-P-K-V-R"} +{"text": "### FUNCTION General inhibitor of family S1 serine proteases ### SEQUENCE -M-R-P-T-P-M-T-A-I-L-A-L-S-L-A-A-A-A-P-A-M-A-A-S-L-K-D-I-A-P-Y-P-E-A-E-K-G-F-T-R-Q-V-I-H-L-P-A-Q-A-D-E-S-A-Y-K-L-E-I-L-A-G-K-T-L-Q-V-D-C-N-R-Q-R-L-G-G-N-L-E-A-H-T-L-E-G-W-G-Y-N-Y-Y-R-L-D-N-V-S-G-P-A-S-T-L-M-A-C-P-D-G-K-K-T-E-A-F-V-P-V-V-G-D-G-F-L-L-R-Y-N-S-K-L-P-V-V-V-Y-V-P-K-D-V-E-V-R-Y-R-V-W-S-A-S-Q-D-V-Q-K-A-K-V-E"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-V-L-S-R-R-I-S-E-P-G-T-R-V-V-S-G-T-V-T-L-D-V-D-S-R-I-K-S-R-L-R-V-T-L-D-D-G-R-E-A-G-L-M-L-E-R-G-H-L-L-R-G-G-E-L-L-A-D-A-E-G-T-Q-L-I-R-V-L-A-A-P-E-A-V-S-T-V-R-C-A-D-P-H-L-L-A-R-A-A-Y-H-L-G-N-R-H-V-P-L-Q-I-E-P-G-L-L-R-F-Q-H-D-H-V-L-D-D-M-L-R-G-L-G-L-T-V-E-A-E-Q-A-P-F-E-P-E-A-G-A-Y-Q-S-A-P-H-G-H-S-H-S-H-A-H-G-H-D-H-P-F-V-R-L-P-A-H-S"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-K-R-H-K-K-I-L-K-L-A-K-G-Y-Y-G-A-R-S-R-V-F-R-V-A-K-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-K-K-R-Q-F-R-A-L-W-I-A-R-I-N-A-G-A-R-T-N-G-L-S-Y-S-R-L-I-A-G-L-K-K-A-S-I-E-I-D-R-K-V-L-A-D-L-A-V-N-E-K-A-A-F-A-A-I-V-E-K-A-K-A-V-L-A"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-T-I-K-R-E-M-R-N-D-K-R-A-V-P-K-A-P-I-N-E-N-I-S-A-R-E-V-R-L-I-G-A-D-G-E-Q-V-G-I-V-S-I-D-E-A-L-R-I-A-D-E-A-K-L-D-L-V-E-I-S-A-D-A-V-P-P-V-C-K-V-M-D-Y-G-K-H-L-F-E-K-K-K-Q-A-N-E-A-K-K-N-Q-K-Q-I-Q-I-K-E-I-K-F-R-P-G-T-E-D-G-D-Y-Q-V-K-L-R-N-L-V-R-F-L-T-D-G-D-K-A-K-I-S-L-R-F-R-G-R-E-M-A-H-Q-E-L-G-M-E-L-L-K-R-V-E-A-D-L-A-E-Y-G-T-V-E-Q-H-P-K-M-E-G-R-Q-L-M-M-V-I-A-P-K-K-K-K"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Expression in Ecoli inhibits cell growth In vivo it is probably neutralized by cognate antitoxin Xre ### SEQUENCE -M-I-L-W-R-I-S-A-Y-A-D-L-S-G-T-G-G-L-R-V-S-G-R-W-H-Q-A-G-R-P-V-V-Y-A-A-T-S-P-P-G-A-M-L-E-V-L-V-H-L-E-I-D-P-E-D-F-P-T-T-M-R-L-L-R-I-E-L-P-D-T-V-S-Q-A-Q-L-P-A-L-Q-P-G-W-S-A-Q-P-E-L-T-R-T-L-G-N-R-F-L-D-D-C-S-A-L-L-L-P-V-P-S-A-I-M-P-S-T-T-N-Y-L-F-N-P-R-H-P-Q-A-Q-S-A-K-I-Q-V-E-D-F-T-P-D-S-R-L-F"} +{"text": "### FUNCTION Probable antitoxin component of a type II toxin-antitoxin system In vivo probably neutralizes the toxic effect of cognate toxin Res ### SEQUENCE -M-S-A-N-A-E-K-E-H-A-M-L-A-E-V-L-R-D-N-G-Y-H-E-Y-R-A-R-L-Q-A-L-L-D-I-P-E-L-A-S-D-F-E-I-H-T-R-I-T-D-G-F-A-A-T-W-L-V-K-L-T-E-R-G-V-L-T-P-V-E-R-D-Q-I-I-P-L-R-T-L-K-S-R-I-E-R-D-Q-P-L-T-V-D-E-S-D-R-L-F-R-S-A-H-I-T-A-M-A-E-A-V-F-G-E-A-G-K-A-K-R-W-L-S-K-P-K-E-R-F-S-G-L-T-P-M-Q-M-L-T-T-Q-Q-G-T-T-Q-V-E-E-M-L-L-Q-I-A-E-G-Y-G-L"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-S-A-I-T-I-T-D-A-A-H-D-Y-L-A-D-L-L-S-K-Q-N-T-P-G-I-G-I-R-I-F-I-T-Q-P-G-T-Q-Y-A-E-T-C-I-A-Y-C-K-P-G-E-E-K-P-D-D-T-A-V-G-L-K-S-F-T-A-Y-L-D-A-V-S-V-P-F-L-E-D-A-L-V-D-Y-A-T-D-R-M-G-G-Q-L-T-I-K-A-P-N-A-K-V-P-M-V-N-E-D-S-P-I-N-E-R-I-N-Y-Y-L-Q-T-E-I-N-P-G-L-A-S-H-G-G-Q-V-S-L-V-D-V-V-D-D-G-I-A-V-L-Q-F-G-G-G-C-Q-G-C-G-Q-A-D-V-T-L-K-E-G-I-E-R-T-L-L-E-R-I-P-E-L-K-G-V-R-D-V-T-D-H-S-Q-K-E-N-A-Y-Y"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-S-T-N-I-I-T-T-E-G-H-E-A-L-K-K-E-L-D-H-L-W-R-V-Y-R-P-E-I-T-Q-K-V-A-W-A-A-S-L-G-D-R-S-E-N-A-D-Y-Q-Y-N-K-K-L-L-R-E-I-D-R-R-V-R-Y-L-R-K-R-L-E-D-V-K-V-V-A-Y-S-P-E-Q-E-G-K-V-F-F-G-A-W-V-E-I-E-N-D-E-G-E-T-M-K-F-R-I-V-G-Y-D-E-I-Y-G-R-N-D-Y-I-S-I-D-S-P-M-A-R-A-L-L-K-K-E-E-G-D-E-V-V-V-H-T-P-T-G-E-A-T-W-Y-V-S-S-I-R-Y-G-Q-G-V-S-T-D"} +{"text": "### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-T-D-F-T-P-D-A-I-L-D-A-T-G-L-N-C-P-E-P-V-M-M-L-H-Q-H-V-R-N-L-A-A-G-G-L-L-K-V-I-A-T-D-P-S-T-R-R-D-I-P-K-F-C-N-F-L-G-H-E-L-L-Q-Q-Q-E-D-A-G-T-F-L-Y-W-I-R-K-K-A-D"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-T-I-E-E-R-V-K-K-I-V-A-E-Q-L-G-V-K-E-E-E-V-T-V-E-K-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-E-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-A-A-I-D-Y-V-K-A-H-Q-A"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-L-P-L-L-L-A-S-S-S-A-Y-R-R-E-L-L-A-R-L-H-L-P-F-T-W-A-S-P-D-I-D-E-Q-R-L-D-G-E-P-P-V-E-L-V-R-R-L-A-R-Q-K-A-E-A-L-A-G-S-H-P-R-H-L-I-I-G-S-D-Q-V-A-V-L-G-E-Q-V-L-G-K-P-H-T-F-E-R-A-C-E-Q-L-L-E-C-S-G-Q-Q-V-S-F-L-T-G-L-A-L-L-N-S-A-T-G-Q-C-Q-V-D-C-V-P-F-T-V-T-L-R-E-L-S-R-E-Q-V-E-R-Y-V-A-A-E-Q-P-L-D-C-A-G-S-F-K-A-E-G-L-G-V-S-L-F-Q-S-T-H-G-C-D-A-T-S-L-I-G-L-P-L-I-R-L-V-D-M-L-T-K-E-G-V-M-V-P"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-T-G-K-E-L-K-P-G-T-V-L-R-I-D-N-D-P-W-L-V-Q-K-A-E-F-T-K-S-G-R-N-S-A-I-M-K-T-K-L-K-N-L-L-T-G-Y-K-T-E-T-V-Y-G-A-D-D-K-L-D-D-V-I-L-D-R-K-E-A-T-L-S-F-I-N-G-D-E-Y-T-F-M-D-T-T-D-Y-T-M-Y-E-L-N-A-E-D-I-E-A-V-L-P-Y-I-E-E-G-M-E-D-V-C-E-A-V-F-F-E-G-R-L-V-S-V-E-L-P-T-T-I-S-R-K-V-V-Y-T-E-N-A-A-R-G-D-T-S-G-K-V-M-K-P-A-K-L-A-N-G-T-E-I-S-V-A-D-F-I-Q-I-D-E-W-I-D-I-D-T-R-D-N-S-F-K-G-R-S-K-K"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-N-L-F-D-F-F-R-G-R-Q-K-Q-T-S-A-S-V-A-K-E-R-L-Q-I-I-V-A-H-E-R-G-Q-R-S-E-P-D-Y-L-P-A-L-Q-K-E-L-L-E-V-I-R-K-Y-V-N-I-G-N-D-D-V-H-I-E-L-E-N-Q-G-S-C-S-I-L-E-L-N-I-T-L-P-D-R"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-S-A-V-L-D-T-P-V-A-I-R-R-T-A-M-D-L-L-A-R-R-E-H-G-R-V-E-L-T-R-K-L-R-Q-R-G-A-S-D-E-L-I-E-P-E-L-D-R-L-A-E-E-G-L-L-S-E-A-R-Y-L-E-S-F-I-R-Y-R-S-G-S-G-Y-G-P-A-R-I-R-E-E-L-C-Q-R-G-L-A-R-A-D-I-D-Q-A-L-R-E-S-E-V-N-W-S-E-R-M-R-D-V-W-Q-R-K-F-A-G-Q-R-P-Q-D-P-R-S-R-A-Q-Q-T-R-F-L-A-Y-R-G-F-P-M-D-M-I-G-R-L-L-S-G-R-D-L-D-D-Y"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-D-I-K-K-D-A-Q-E-R-M-G-K-S-I-E-A-L-S-R-N-L-A-A-I-R-T-G-R-A-H-P-S-I-L-D-S-V-K-V-T-A-W-G-S-E-M-P-L-N-Q-V-A-A-I-T-V-E-D-A-R-T-L-K-I-V-A-H-D-K-N-L-S-A-A-I-E-K-A-I-L-T-S-D-L-G-L-N-P-S-S-A-G-T-T-I-R-V-P-M-P-A-L-T-E-E-T-R-K-G-Y-T-K-Q-A-S-G-V-A-E-D-A-K-V-A-V-R-N-V-R-R-D-A-L-A-D-L-K-K-L-T-K-D-K-E-I-S-E-D-E-E-R-R-A-A-D-E-I-Q-K-L-T-D-K-F-V-A-E-V-D-A-A-F-K-A-K-E-K-D-L-M-A-V"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-T-N-K-I-I-Q-Q-L-E-A-E-Q-M-S-K-E-I-P-T-F-A-P-G-D-T-V-V-V-Q-V-K-V-K-E-G-E-R-S-R-L-Q-A-F-E-G-V-V-I-A-K-R-N-R-G-L-N-S-A-F-T-V-R-K-I-S-S-G-V-G-V-E-R-T-F-Q-T-Y-S-P-Q-I-D-S-L-A-V-K-R-R-G-D-V-R-K-A-K-L-Y-Y-L-R-D-L-S-G-K-A-A-R-I-K-E-K-L-S"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-N-A-T-P-E-K-A-D-D-L-I-V-V-G-K-I-F-S-V-H-G-V-R-G-E-V-K-V-Y-S-F-T-D-P-I-E-N-L-L-D-Y-P-R-W-T-L-R-H-E-G-K-V-K-Q-V-E-L-V-S-G-R-G-S-Q-K-G-L-V-V-K-L-K-G-L-D-D-R-D-E-A-R-L-L-S-G-Y-E-I-C-I-P-R-S-L-L-P-N-L-A-A-D-E-Y-Y-W-Y-Q-L-V-G-L-K-V-I-N-Q-D-E-Q-L-F-G-K-V-D-H-L-L-E-T-G-A-N-D-V-M-V-V-K-P-C-A-G-S-L-D-D-R-E-R-L-L-P-Y-T-E-Q-C-V-L-A-I-D-L-E-A-G-V-M-R-V-E-W-D-A-D-F"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-L-R-P-L-H-D-R-V-V-I-R-R-S-E-E-E-S-K-T-A-G-G-I-V-L-P-G-S-A-A-E-K-P-N-R-G-E-V-V-A-V-G-T-G-R-V-L-D-N-G-E-V-R-A-L-A-V-K-V-G-D-K-V-V-F-G-P-Y-S-G-S-N-T-V-K-V-D-G-E-D-L-L-V-M-A-E-N-E-I-L-A-V-V-E-G"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-T-A-K-P-E-T-V-K-R-E-W-F-V-V-D-A-A-G-Q-T-L-G-R-L-A-T-E-I-A-T-R-L-R-G-K-H-K-P-E-Y-T-P-H-V-D-T-G-D-Y-I-V-V-I-N-A-E-Q-V-R-V-T-G-A-K-S-S-D-K-M-Y-Y-S-H-S-G-F-P-G-G-I-K-E-I-N-F-E-K-L-I-A-K-A-P-E-R-V-I-E-T-A-V-K-G-M-L-P-K-N-P-L-G-R-D-M-Y-R-K-L-K-V-Y-A-G-A-A-H-P-H-T-A-Q-Q-P-Q-E-L-K-I"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-E-L-R-F-T-E-D-H-E-W-L-R-V-E-A-D-G-S-V-T-V-G-I-T-A-Y-A-Q-N-A-L-G-D-V-V-F-V-Q-L-P-E-L-Q-Q-Y-E-K-G-N-E-A-S-T-V-E-S-V-K-A-A-S-G-V-Y-M-P-L-T-G-E-V-V-E-V-N-G-Q-L-E-D-S-P-E-L-V-N-E-D-P-M-G-E-G-W-F-F-R-F-I-P-A-D-A-E-A-V-T-A-L-L-D-Q-D-A-Y-D-R-L-L-K-A-N-D-D-A"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-G-T-P-C-H-Y-A-L-F-D-L-Q-P-S-F-R-L-D-L-D-K-L-A-T-R-Y-R-E-L-A-R-E-V-H-P-D-R-F-A-D-A-S-E-R-E-Q-R-I-A-L-E-K-S-A-A-L-N-D-A-Y-Q-T-L-R-S-A-P-R-R-A-R-Y-L-L-A-I-S-G-H-E-V-P-Q-E-V-T-V-H-D-P-D-F-L-L-Q-Q-M-Q-W-R-E-E-L-E-E-L-Q-D-E-A-D-L-D-G-V-G-V-F-K-K-R-L-K-A-A-Q-D-T-L-N-E-D-F-A-G-C-W-D-A-P-G-E-R-D-K-A-E-R-L-M-R-R-M-Q-F-L-D-K-L-A-Q-E-V-R-Q-L-E-E-R-L-D-D"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-T-E-F-T-L-N-A-Q-A-R-T-D-L-G-K-G-A-S-R-R-L-R-H-S-A-N-I-P-A-V-V-Y-G-G-N-Q-D-A-Q-S-L-T-I-L-A-K-E-I-T-K-L-F-E-N-E-A-A-F-S-H-V-L-E-L-N-V-D-G-A-K-Q-N-V-V-V-K-A-L-Q-R-H-P-A-K-G-F-I-M-H-A-D-F-V-R-V-V-A-G-Q-K-L-T-A-K-V-P-V-H-F-I-N-E-E-A-P-V-K-K-G-G-E-I-S-H-V-E-S-E-I-E-V-S-C-E-A-K-D-L-P-E-F-I-E-V-D-L-A-N-A-E-I-G-T-I-I-H-L-S-D-L-K-A-P-K-G-V-E-F-V-A-L-A-H-G-D-D-K-A-V-A-N-V-H-A-P-R-V-A-P-E-A-E-G-A-A-E"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-A-I-Q-L-I-V-G-L-G-N-P-G-P-E-Y-E-Q-T-R-H-N-A-G-A-L-F-V-E-R-L-A-S-A-Q-R-V-S-L-T-A-D-K-K-Y-F-G-L-T-A-K-F-S-H-Q-G-N-D-V-R-L-L-I-P-T-T-Y-M-N-R-S-G-Q-S-V-A-A-L-A-N-F-F-R-I-K-P-E-A-I-L-V-A-H-D-E-L-D-L-P-P-G-V-A-K-L-K-R-G-G-G-H-G-G-H-N-G-L-R-D-I-I-A-Q-L-G-N-Q-N-D-F-H-R-L-R-L-G-I-G-H-P-G-D-A-K-L-V-S-N-F-V-L-G-R-A-P-R-A-E-Q-E-K-L-D-A-S-I-D-F-A-L-G-V-L-P-D-V-L-A-G-D-F-A-K-A-M-R-E-L-H-S-Q-K-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-Y-A-V-I-V-T-G-G-K-Q-Y-K-V-A-E-G-E-F-L-K-I-E-K-L-E-V-A-T-G-E-S-V-T-F-D-R-V-L-L-V-A-N-G-E-E-V-T-I-G-A-P-V-V-A-G-A-K-V-V-A-E-V-V-S-Q-G-R-H-D-K-V-R-I-I-K-F-R-R-R-K-H-H-M-K-R-M-G-H-R-Q-W-F-T-E-I-K-I-T-G-I-Q-A"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-S-Q-P-L-T-V-D-C-P-T-C-G-A-P-V-E-W-S-E-K-N-A-F-R-P-F-C-S-D-R-C-K-L-I-D-L-G-A-W-A-A-E-E-H-K-I-A-G-S-E-E-S-E-D-E-L-Y-S-G-D-L-E-P-R-H"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-P-S-A-K-K-R-A-K-Q-A-E-K-R-R-S-H-N-A-S-L-R-S-M-V-R-T-Y-I-K-N-V-V-K-A-I-D-A-K-D-A-E-K-A-Q-A-A-Y-V-L-A-V-P-V-I-D-R-M-A-D-K-G-I-I-H-K-N-K-A-A-R-H-K-G-R-L-N-G-H-I-K-A-L-K-E-A-A-A-A"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-R-K-K-A-S-L-D-F-E-Q-S-L-A-D-L-Q-A-L-V-E-R-L-E-N-G-E-L-S-L-E-E-S-L-A-A-F-E-Q-G-I-A-L-T-R-D-C-Q-G-A-L-A-Q-A-E-Q-K-V-Q-I-L-L-E-R-D-G-E-L-A-A-Q-P-F-D-A-E-P-E-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-I-S-D-E-S-D-R-F-N-P-R-D-P-K-P-A-D-A-G-K-P-S-K-S-A-K-R-R-E-A-R-K-L-A-T-Q-A-L-Y-Q-W-H-M-A-Q-H-S-L-N-E-I-E-A-Q-F-R-V-D-N-D-F-T-D-V-D-G-A-Y-F-R-E-I-L-H-G-V-P-A-I-K-G-E-I-D-K-A-L-V-P-C-M-T-I-A-L-E-E-L-D-P-V-E-L-A-V-L-R-L-S-T-W-E-L-I-K-R-V-D-V-P-Y-R-V-V-I-N-E-G-V-E-L-A-K-V-F-G-A-T-D-G-H-K-F-V-N-G-V-L-D-K-L-A-P-A-L-R-E-A-E-V-K-A-N-K-R"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-G-A-N-D-T-K-V-I-D-S-R-L-V-A-E-G-E-Q-V-R-R-R-R-E-C-V-A-C-G-E-R-F-T-T-F-E-T-A-E-L-V-L-P-R-L-I-K-Q-D-G-T-R-Q-P-F-D-E-E-K-L-R-A-G-M-Q-R-A-L-E-K-R-P-V-S-V-E-R-L-E-A-A-L-A-H-I-K-S-R-L-R-A-T-G-E-R-E-V-K-S-L-V-V-G-E-M-V-M-A-E-L-R-K-L-D-E-V-A-Y-I-R-F-A-S-V-Y-R-R-F-Q-D-L-D-E-F-R-E-E-I-D-R-L-A-R-E-P-A-K-E"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-R-G-V-N-K-V-I-L-V-G-T-C-G-Q-D-P-E-V-R-Y-L-P-N-G-N-A-V-T-N-L-S-L-A-T-S-E-Q-W-T-D-K-Q-S-G-Q-K-V-E-R-T-E-W-H-R-V-S-L-F-G-K-V-A-E-I-A-G-E-Y-L-R-K-G-S-Q-C-Y-I-E-G-K-L-Q-T-R-E-W-E-K-D-G-I-K-R-Y-T-T-E-I-I-V-D-I-N-G-T-M-Q-L-L-G-G-R-P-Q-G-Q-Q-Q-G-G-D-P-Y-N-Q-G-G-G-N-Y-G-G-G-Q-Q-Q-Q-Y-N-Q-A-P-P-R-Q-Q-A-Q-R-P-Q-Q-A-P-Q-R-P-A-P-Q-Q-P-A-P-Q-P-A-A-D-F-D-S-F-D-D-D-I-P-F"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-D-N-K-H-T-V-I-S-L-T-Y-I-Y-G-V-G-R-T-T-A-Q-K-I-C-A-D-A-G-V-N-P-A-A-K-I-K-D-L-S-D-E-Q-I-E-T-L-R-G-E-V-A-K-F-T-T-E-G-D-L-R-R-D-I-N-M-K-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-K-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-R-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-D-L-S-P-A-P-G-S-R-R-E-K-H-R-P-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-T-S-R-S-G-G-S-I-A-P-G-F-E-G-G-Q-Q-P-L-H-R-R-L-P-K-F-G-F-V-S-L-K-A-M-D-R-A-E-V-R-L-S-E-L-A-K-V-E-G-D-V-I-S-V-Q-S-L-K-D-A-N-V-I-N-Q-H-I-Q-R-V-K-I-M-L-S-G-E-V-T-R-A-V-T-I-K-G-I-A-A-T-K-G-A-R-A-A-I-E-A-A-G-G-K-F-E-E"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-N-N-D-Q-K-R-D-E-G-Y-I-E-K-L-V-Q-V-N-R-V-A-K-T-V-K-G-G-R-I-F-T-F-T-A-L-T-V-V-G-D-G-K-G-R-V-G-F-G-R-G-K-S-R-E-V-P-A-A-I-Q-K-A-M-E-A-A-R-R-N-M-I-Q-V-D-L-K-G-T-T-L-Q-Y-A-T-K-A-A-H-G-A-S-K-V-Y-M-Q-P-A-S-E-G-T-G-I-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-Q-N-V-L-A-K-C-Y-G-S-T-N-P-V-N-V-V-Y-A-T-F-K-G-L-K-A-M-Q-S-P-E-S-I-A-A-K-R-G-K-S-V-E-E-I-F"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-T-D-K-K-V-I-R-L-R-R-A-R-K-A-R-L-K-M-H-E-L-E-V-V-R-L-C-V-F-R-S-S-Q-H-I-Y-A-Q-V-I-S-A-D-G-S-K-V-L-A-S-A-S-T-L-D-K-D-L-R-D-G-A-T-G-N-I-D-A-A-T-K-V-G-K-L-V-A-E-R-A-K-A-A-G-V-S-Q-V-A-F-D-R-S-G-F-K-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-G-G-L-E-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-N-P-V-K-L-P-S-G-V-E-V-K-F-A-G-Q-Q-L-S-V-K-G-A-K-G-T-L-E-L-N-V-H-S-S-V-E-V-T-E-E-S-G-E-L-R-F-V-A-R-N-G-D-Q-Q-A-R-A-M-A-G-T-T-R-A-L-V-N-N-M-V-Q-G-V-S-Q-G-F-E-R-K-L-Q-L-V-G-V-G-Y-K-A-Q-A-K-G-T-V-L-N-L-A-L-G-F-S-H-P-V-D-Y-E-L-P-A-G-I-T-A-E-T-P-S-Q-T-D-I-L-I-K-G-I-D-K-Q-L-V-G-Q-V-A-A-E-I-R-D-F-R-P-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-V-V-R-R-K-E-A-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-L-A-D-M-L-T-R-I-R-N-A-Q-M-A-E-K-S-V-V-S-M-P-S-S-T-L-K-V-A-V-A-K-V-L-K-D-E-G-Y-I-A-G-Y-Q-V-T-G-E-A-K-P-S-L-S-I-E-L-K-Y-F-E-G-R-P-V-I-E-E-L-K-R-S-S-R-P-G-L-R-Q-Y-K-A-V-T-D-L-P-K-V-R-G-G-L-G-V-S-I-V-S-T-N-K-G-V-M-T-D-R-A-A-R-A-A-G-V-G-G-E-V-L-C-T-V-F"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-K-N-R-E-L-K-R-Q-L-T-V-A-K-F-A-K-K-R-A-E-L-K-A-T-I-V-N-L-N-A-S-P-E-E-R-F-A-A-V-V-A-L-Q-K-Q-P-R-D-A-S-A-S-R-L-R-N-R-C-R-L-T-G-R-P-H-G-V-Y-R-K-F-G-L-G-R-N-M-L-R-Q-A-A-M-R-G-D-V-P-G-L-V-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-R-L-K-E-I-Y-R-N-E-I-A-P-K-L-K-E-E-L-K-L-S-N-V-M-E-V-P-R-V-T-K-I-T-L-N-M-G-L-G-E-A-I-G-D-K-K-V-I-E-H-A-V-A-D-L-E-K-I-T-G-Q-K-P-V-V-T-F-A-R-K-S-I-A-G-F-K-V-R-E-G-W-P-I-G-V-K-V-T-L-R-S-D-K-M-Y-E-F-L-D-R-L-L-A-I-S-L-P-R-V-R-D-F-R-G-L-N-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-K-E-Q-I-I-F-P-E-I-D-Y-D-K-I-D-A-L-R-G-L-D-I-T-L-T-T-T-A-R-S-D-D-E-G-R-A-L-L-R-A-F-K-F-P-F-R-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-K-I-R-R-D-D-E-I-I-V-I-A-G-K-D-K-G-K-R-G-K-V-L-K-V-L-A-D-D-R-L-V-I-G-G-V-N-L-V-K-R-H-T-K-P-N-P-M-A-G-V-Q-G-G-I-V-E-K-E-A-P-L-H-A-S-N-V-A-I-F-N-G-E-T-N-K-A-D-R-V-G-F-K-V-E-D-G-K-K-I-R-V-F-K-S-T-Q-K-A-V-D-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-T-Q-S-M-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-G-I-G-D-I-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-Q-V-M-T-A-V-V-V-R-T-R-H-G-V-R-R-A-D-G-S-I-I-R-F-D-G-N-A-A-V-L-L-N-N-K-Q-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-K-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-E-A-E-K-T-V-R-T-L-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-L-I-E-R-R-V-K-H-P-I-Y-G-K-Y-V-K-R-S-T-K-L-H-A-H-D-E-A-N-Q-C-K-I-G-D-K-V-S-I-R-E-T-R-P-L-A-K-T-K-S-W-A-L-V-E-V-L-E-R-A-V-E-V"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-Q-M-T-G-H-N-R-G-L-A-L-R-G-S-K-V-S-F-G-E-F-A-L-K-A-V-A-R-G-R-L-T-A-R-Q-I-E-S-A-R-R-A-L-T-R-H-V-K-R-G-G-K-I-W-I-R-V-F-P-D-K-P-I-S-K-K-P-L-E-V-R-M-G-K-G-K-G-S-V-E-Y-W-V-A-Q-I-Q-P-G-K-V-L-Y-E-I-E-G-V-S-E-E-L-A-R-E-A-F-A-L-A-A-A-K-L-P-L-A-T-S-F-V-K-R-T-V-M"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-V-A-A-K-L-S-G-A-R-I-S-A-Q-K-A-R-L-V-A-D-Q-I-R-G-K-K-V-G-E-A-L-N-L-L-A-F-S-S-K-K-A-A-E-I-M-K-K-V-L-E-S-A-V-A-N-A-E-H-N-E-G-A-D-V-D-D-L-K-V-S-T-V-F-V-N-E-G-R-S-L-K-R-I-M-P-R-A-K-G-R-A-D-R-I-V-K-R-S-C-H-I-T-V-K-V-A-D-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-V-E-V-A-V-E-K-N-D-R-K-P-V-K-T-W-S-R-R-S-M-I-L-P-Q-M-V-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-L-V-N-E-D-M-V-G-H-K-L-G-E-F-A-G-T-R-T-Y-R-G-H-V-A-D-K-K-A-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-Q-E-R-V-F-K-V-L-L-G-P-H-V-S-E-K-A-T-V-L-A-E-K-K-G-Q-F-V-F-K-V-A-T-D-A-T-K-L-E-I-K-K-A-V-E-G-L-F-N-V-K-V-E-N-V-S-T-V-N-V-L-G-K-T-K-R-T-A-R-G-L-G-K-R-N-D-W-K-K-A-I-V-S-L-Q-P-G-Q-D-L-D-F-S-S-S-A-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA It is important during the early stages of 50S assembly It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-Q-L-N-V-N-D-A-Q-A-I-E-V-S-E-L-T-F-G-G-E-F-N-E-T-L-V-H-Q-A-V-V-A-Y-M-A-G-G-R-Q-G-T-K-Q-Q-K-T-R-S-D-V-A-G-G-G-K-R-P-W-R-Q-K-G-T-G-R-A-R-A-G-T-T-R-G-P-I-W-R-G-G-G-V-T-F-A-A-R-P-Q-D-H-S-Q-K-L-N-K-K-M-Y-R-A-A-L-R-S-I-L-A-E-L-V-R-S-D-R-L-V-V-V-Q-D-F-A-V-E-A-P-K-T-K-D-L-L-N-K-L-N-G-M-G-L-S-D-V-L-I-V-S-D-A-V-D-Q-N-L-Y-L-A-A-R-N-L-P-H-V-D-V-R-D-V-Q-G-S-D-P-V-S-L-I-A-Y-E-K-V-L-I-T-V-S-A-V-K-K-F-E-E-L-L-G"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-Q-I-R-I-R-L-K-A-F-D-H-R-L-I-D-Q-S-T-Q-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-R-F-T-V-L-V-S-P-H-V-N-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-V-L-D-I-V-Q-P-T-D-K-T-V-D-A-L-M-K-L-D-L-A-A-G-V-E-V-Q-I-S-L-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-A-A-K-R-E-I-L-D-D-P-K-Y-G-S-Q-I-L-A-K-F-M-N-H-V-M-E-S-G-K-K-A-V-A-E-R-I-V-Y-G-A-L-D-T-V-K-A-R-K-N-S-D-P-L-E-I-F-E-K-A-L-D-A-I-A-P-L-V-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-P-S-R-R-N-A-L-A-M-R-W-L-V-D-Y-A-R-K-R-G-E-K-S-M-A-L-R-L-A-G-E-L-L-D-A-A-E-G-K-G-A-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-S-H-Y-R-F"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-N-Q-L-V-R-Q-P-R-K-R-S-V-E-K-S-D-V-P-A-L-Q-N-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-S-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-S-L-D-T-S-G-V-K-G-R-N-Q-G-R-S-K-Y-G-T-K-R-P-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-I-K-L-E-D-K-K-A-I-V-A-E-V-N-E-A-A-K-V-A-L-S-A-V-V-A-D-A-R-G-V-T-V-S-A-M-T-G-L-R-K-E-A-R-E-A-G-V-Y-V-R-V-V-R-N-T-L-L-K-R-A-V-E-G-T-E-F-S-I-L-N-D-A-F-K-G-P-T-L-I-A-F-S-N-E-H-P-G-A-A-A-R-L-F-K-E-F-A-K-G-Q-D-K-F-E-I-K-A-A-A-F-D-G-N-F-I-A-A-N-Q-I-D-V-L-A-T-L-P-T-R-D-E-A-I-A-R-L-M-S-V-I-Q-G-A-T-S-K-L-A-R-T-L-A-A-I-R-D-Q-K-E-A-T-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-Q-A-Y-I-K-L-Q-V-K-A-G-Q-A-N-P-S-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-F-N-A-R-T-Q-G-Q-E-A-G-L-P-T-P-V-I-I-T-V-Y-S-D-R-S-F-T-F-E-T-K-S-T-P-A-S-V-L-L-K-K-A-A-G-L-T-S-G-S-A-R-P-N-T-V-K-V-G-T-V-T-R-A-Q-L-E-D-I-A-K-A-K-Q-A-D-L-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-N-V-E-G-V"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-V-E-T-F-T-P-T-G-L-E-F-T-H-G-A-A-Q-K-V-K-N-L-V-N-E-E-G-N-E-R-L-K-L-R-V-F-V-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-D-V-A-E-D-D-T-I-V-E-R-E-G-V-S-L-V-V-D-P-M-S-F-Q-Y-L-A-G-A-E-V-D-Y-Q-E-G-L-E-G-S-R-F-V-I-K-N-P-N-A-A-T-T-C-G-C-G-S-S-F-S-I"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-S-E-F-K-R-I-P-P-E-Q-A-L-E-L-R-K-K-E-G-A-V-V-V-D-I-R-D-P-Q-A-F-A-A-G-H-I-T-G-A-R-H-L-D-N-H-S-V-A-D-F-I-R-N-A-D-L-D-A-P-T-L-V-V-C-Y-H-G-N-S-S-Q-S-A-A-A-Y-L-V-G-Q-G-F-S-D-V-Y-S-V-D-G-G-F-E-L-W-R-A-T-Y-P-A-E-T-A-Q-G-N-A-E"} +{"text": "### FUNCTION Required for coenzyme pyrroloquinoline quinone ### SEQUENCE -M-W-T-K-P-A-Y-T-D-L-R-I-G-F-E-V-T-M-Y-F-A-N-R"} +{"text": "### FUNCTION Probably forms a two-component reduced flavin mononucleotide-dependent monooxygenase by binding to SsuD Required for growth on aliphatic sulfonates or methionine but not arylsulfonates ### SEQUENCE -M-L-V-V-S-I-G-G-S-P-S-L-R-S-R-S-G-V-L-L-E-R-S-R-Q-W-L-Q-D-R-G-V-E-V-V-T-F-Q-V-R-D-F-P-A-E-D-L-L-H-A-R-F-D-S-P-H-V-Q-H-F-Q-Q-L-V-A-Q-A-D-G-L-I-V-S-T-P-V-Y-K-A-S-F-S-G-A-L-K-T-L-L-D-L-L-P-E-R-A-L-A-H-K-I-V-L-P-I-A-T-G-G-S-I-A-H-M-L-A-V-D-Y-A-L-K-P-V-L-S-A-L-K-A-Q-E-T-L-Q-G-I-F-A-D-D-S-Q-V-A-Y-A-E-G-T-K-P-A-Q-L-V-Q-A-L-E-E-R-L-H-D-S-L-E-T-F-H-V-A-L-A-R-R-P-R-P-V-A-P-G-V-L-N-E-R-L-I-S-A-R-W-S-I"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-I-L-N-I-L-E-F-P-D-P-R-L-R-T-L-A-K-P-V-T-E-F-D-D-A-L-R-Q-L-I-D-D-M-F-E-T-M-Y-E-A-P-G-I-G-L-A-A-T-Q-V-N-V-H-K-Q-V-V-V-M-D-L-S-E-D-R-S-E-P-R-V-F-I-N-P-S-V-E-E-L-T-H-D-M-G-Q-Y-Q-E-G-C-L-S-V-P-G-F-Y-E-N-V-D-R-P-L-R-V-R-V-K-A-Q-D-R-D-G-K-P-F-E-L-E-C-E-G-L-L-A-V-C-V-Q-H-E-F-D-H-L-N-G-K-L-F-V-D-Y-L-S-Q-L-K-R-D-R-I-K-K-K-L-E-K-Q-H-R-Q-Q-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-R-K-S-Y-R-V-K-K-E-T-E-F-Q-Q-V-F-E-T-R-N-S-Y-A-N-R-Q-F-V-I-Y-V-L-E-K-P-G-Q-P-H-F-R-V-G-I-S-V-G-K-K-I-G-N-A-V-A-R-N-W-V-K-R-R-I-R-Q-S-I-T-E-L-K-P-Q-L-K-Q-D-A-D-F-L-V-I-A-R-P-T-V-A-G-K-S-Q-A-E-T-K-A-Y-L-S-H-A-L-K-L-A-H-L-L-D-N-D"} +{"text": "### FUNCTION May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor ### SEQUENCE -M-E-K-P-E-Q-K-L-L-L-Y-K-L-S-D-R-L-F-A-A-I-Q-K-N-L-Q-L-E-R-R-Q-A-L-L-V-K-L-G-I-D-T-V-L-N-V-I-P-K-L-I-I-T-I-I-L-A-L-L-L-H-E-L-V-P-V-L-V-F-M-G-S-F-L-V-L-R-G-F-A-Y-G-R-H-L-E-S-D-L-L-C-T-I-L-T-A-V-T-F-V-G-V-P-Y-L-I-Q-F-T-D-G-I-P-E-L-F-R-F-I-L-C-L-L-L-T-V-P-I-G-M-F-S-P-A-V-T-R-K-N-P-I-K-S-Q-S-L-K-R-A-L-K-H-K-A-I-I-T-S-L-V-F-S-F-L-Q-F-L-V-S-N-N-L-G-T-I-I-V-V-S-L-L-L-V-F-T-L-I-V-P-L-K-G-G-K-S-D-E-A-E-N-V"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-L-D-N-L-T-I-A-S-R-Y-S-K-A-L-F-E-L-A-V-E-K-D-Q-T-E-A-F-L-A-E-L-K-Q-L-R-Q-V-F-V-D-N-P-Q-L-A-E-V-L-S-G-S-L-L-P-V-D-Q-K-Q-T-T-L-S-T-L-T-D-H-A-S-E-Y-I-K-N-F-I-Q-M-L-Y-D-Y-G-R-M-S-N-L-V-G-I-V-D-A-F-E-A-R-F-D-E-S-R-K-I-V-H-A-E-V-T-S-A-V-K-L-S-D-E-Q-A-D-A-I-A-K-A-F-A-K-R-V-G-A-N-Q-V-V-L-S-R-K-V-D-E-A-I-I-G-G-V-I-V-K-S-N-N-Q-T-F-D-G-S-V-A-L-Q-L-T-N-L-R-R-A-L-I-N-N"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-D-N-A-K-S-L-T-V-S-I-V-T-P-D-G-Q-V-Y-E-N-K-T-P-M-L-I-V-R-T-I-D-G-E-L-G-I-L-P-N-H-I-P-V-I-A-S-L-A-I-D-E-V-R-I-K-Q-L-E-S-D-Q-E-D-D-E-I-A-V-N-G-G-F-V-E-F-S-N-N-T-A-T-I-V-A-D-S-A-E-R-Q-N-D-I-D-V-A-R-A-E-N-A-R-K-R-A-E-T-R-I-Q-N-A-Q-Q-K-H-D-D-A-E-L-A-R-A-Q-V-A-L-R-R-A-M-N-R-L-N-V-A-R-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-R-L-L-M-K-G-I-R-F-Y-Q-R-A-F-S-A-F-S-P-A-H-C-R-Y-Y-P-T-C-S-N-Y-T-L-E-A-I-N-R-F-G-A-V-K-G-V-L-M-G-V-A-R-I-L-R-C-Q-P-L-V-K-G-G-F-D-P-V-P-A-H-F-S-L-R-R-N-P-Q-Y-K-E-E-D-H-R-G-K-K-R"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-K-L-M-G-L-D-V-G-S-R-T-V-G-V-A-I-S-D-A-F-G-W-T-A-Q-G-V-E-I-I-R-I-N-E-D-A-E-E-F-G-I-D-R-V-A-E-L-V-E-E-L-D-A-G-G-F-V-L-G-L-P-K-N-M-N-N-T-L-G-P-R-A-E-A-A-Q-H-Y-G-E-L-L-T-A-R-F-H-L-P-V-D-F-E-D-E-R-L-T-T-V-E-A-E-R-M-L-V-E-E-A-N-T-S-R-K-K-R-K-K-V-I-D-K-L-A-A-S-L-I-L-Q-N-Y-L-D-R-H-G-K-L-T-Q-E"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-I-L-Y-T-A-P-S-C-T-S-C-R-K-A-K-A-W-L-Q-T-H-D-I-D-F-Q-E-H-N-L-F-T-E-P-L-S-I-E-K-I-K-Q-I-L-Q-L-T-E-S-G-T-E-E-I-I-S-T-R-S-K-A-F-Q-Q-L-N-V-D-I-N-D-L-S-L-N-E-L-F-D-M-I-T-H-D-P-S-L-L-R-R-P-I-M-L-D-E-K-R-L-Q-V-G-Y-N-E-D-E-I-R-R-F-L-P-R-K-I-R-T-L-E-L-L-R-A-Q-Q-L-A-N-M"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-E-K-R-I-E-A-T-V-A-K-Y-A-E-R-R-Q-A-L-K-A-A-G-N-Y-T-E-L-A-K-L-P-R-N-A-S-P-V-R-I-H-R-R-D-S-L-D-G-R-P-H-A-Y-L-R-K-F-G-M-S-R-L-N-F-R-R-L-A-H-A-G-Q-I-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-G-F-I-S-N-F-F-G-V-G-D-S-D-S-Q-Y-E-E-P-T-E-A-S-Q-A-A-A-P-T-E-S-A-T-N-T-R-S-T-P-K-V-V-P-M-Q-G-G-K-S-V-N-S-K-I-A-L-F-E-P-K-I-Y-S-D-V-K-E-I-A-T-Q-L-L-K-N-Q-A-V-I-I-N-F-D-H-V-D-D-E-M-A-R-R-I-V-D-F-L-T-G-T-V-F-A-I-N-G-E-I-E-R-I-G-D-E-I-F-L-C-I-P-E-N-Y-E-V-S-G-S-T-T-S-Q-F-D-T-S-K-L"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-Y-Y-Q-E-T-K-E-R-N-P-Q-R-E-T-T-Q-S-L-Y-L-E-A-E-T-E-V-A-A-R-T-L-V-E-D-N-T-D-H-N-I-E-F-I-E-P-L-E-G-N-F-L-D-Y-E-Q-K-N-P-E-Y-H-L-T-E-F-N-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-K-M-R-D-I-I-R-E-G-N-H-T-L-R-A-E-A-K-Q-V-K-F-P-L-S-E-A-D-Q-K-L-A-N-D-M-M-E-Y-L-E-N-S-Q-D-P-E-L-A-K-K-Y-G-L-R-A-G-V-G-L-A-A-P-Q-V-D-V-S-E-Q-M-A-A-V-L-V-P-S-E-N-E-D-D-E-P-V-F-K-D-V-I-I-N-P-V-I-I-S-H-S-V-Q-P-G-A-L-T-E-G-E-G-C-L-S-V-D-R-D-I-A-G-Y-V-I-R-H-D-R-I-T-L-R-Y-Y-N-M-A-G-E-E-K-K-I-R-L-K-N-Y-P-A-I-V-C-Q-H-E-I-D-H-L-H-G-I-L-F-Y-D-H-I-N-G-D-N-P-F-A-A-D-D-D-L-V-L-I-S"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-I-I-K-S-A-I-E-R-V-K-T-N-N-K-A-N-V-R-N-T-A-Q-M-S-A-M-R-T-A-V-K-K-F-E-A-A-K-T-A-G-A-D-N-V-D-D-L-Y-L-A-A-T-S-A-V-D-K-A-A-S-K-G-L-I-K-R-N-K-A-A-R-D-K-S-R-M-A-A-R-Y-A-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-R-E-K-K-T-E-L-I-N-K-Y-A-R-H-E-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-E-D-I-N-E-L-N-E-H-L-R-V-H-K-K-D-F-H-S-Q-R-G-L-M-K-K-I-G-H-R-R-N-L-L-A-Y-L-R-K-E-D-V-N-R-Y-R-D-L-I-Q-S-L-G-L-R-R"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-E-V-H-N-V-E-L-V-M-S-A-V-A-P-S-Q-Y-P-T-T-G-F-P-E-I-G-L-A-G-R-S-N-V-G-K-S-S-L-I-N-V-L-I-N-R-N-S-Y-A-R-T-S-S-Q-P-G-K-T-Q-T-L-N-F-Y-K-V-E-D-Q-L-Y-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-K-E-R-E-K-W-G-Q-M-I-E-T-Y-L-T-S-R-E-T-L-R-G-V-V-I-L-V-D-A-R-H-A-P-T-K-D-D-V-A-M-Y-E-W-M-R-Y-Y-E-M-P-L-L-V-V-A-T-K-S-D-K-I-P-R-G-K-W-N-K-Q-E-S-L-I-K-K-T-L-N-F-Q-A-E-D-D-F-I-A-F-S-A-K-T-K-E-G-K-D-A-V-W-Q-W-I-E-A-H-T-V-G-G-N"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-A-L-D-L-K-K-Y-V-A-S-I-P-D-Y-P-E-P-G-I-I-F-R-D-I-S-P-L-M-A-D-G-E-A-Y-R-E-A-T-D-Q-I-V-Q-F-A-R-D-K-H-V-D-M-I-V-G-P-E-A-R-G-F-I-V-G-C-P-V-A-Y-E-L-G-V-G-F-A-P-A-R-K-K-G-K-L-P-R-E-T-V-K-A-T-Y-D-L-E-Y-G-Q-S-A-L-Y-L-H-K-D-A-I-K-P-G-Q-N-V-L-V-T-D-D-L-L-A-T-G-G-T-I-S-A-T-I-Q-M-V-E-E-L-G-G-N-V-V-G-T-A-F-L-V-E-L-K-E-L-H-G-R-D-K-I-K-D-Y-D-M-L-S-L-M-Q-F"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-I-T-E-P-I-L-K-E-A-Q-E-R-M-K-K-A-E-A-A-L-Q-R-E-L-G-N-I-R-A-G-R-A-N-A-S-L-L-N-R-I-S-A-D-Y-Y-G-A-Q-T-P-L-N-Q-M-A-A-I-T-V-P-E-P-R-V-L-M-V-T-P-F-D-K-S-A-L-K-E-I-E-K-A-I-L-A-S-D-L-G-I-S-P-A-N-D-G-S-A-I-R-L-V-I-P-Q-L-T-E-E-R-R-K-E-L-A-K-D-V-K-A-E-G-E-R-A-K-V-A-V-R-N-V-R-R-D-A-M-E-A-L-K-K-G-H-K-D-G-Q-F-T-D-D-Q-L-H-Q-L-E-D-Q-A-Q-K-L-T-D-Q-A-G-K-D-V-D-A-I-V-A-D-K-E-K-E-I-L-E-G"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-S-N-V-V-E-T-I-Q-P-V-A-A-A-I-V-S-A-H-Q-F-E-L-V-D-L-E-F-V-R-E-G-Q-S-W-Y-L-R-L-Y-I-D-K-P-G-G-I-N-I-E-E-C-A-M-V-S-D-E-L-S-E-K-L-D-A-M-E-P-D-P-I-P-Q-A-Y-F-L-E-V-S-S-P-G-A-E-R-P-L-K-K-E-A-D-F-Q-N-A-I-G-K-Y-V-H-V-G-L-Y-Q-K-L-D-G-K-K-I-F-E-G-D-L-T-A-V-T-P-T-T-L-T-I-D-Y-L-D-K-T-R-H-K-T-V-T-I-N-R-E-Q-I-S-Q-A-R-L-A-V-K-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-Q-H-Y-R-V-G-R-L-E-Q-E-I-E-R-E-V-N-D-I-L-L-K-R-V-R-D-P-R-V-A-G-V-T-I-T-G-V-T-V-T-G-D-L-Q-Q-A-T-I-Y-Y-S-I-L-S-D-K-A-S-D-G-E-K-T-A-A-G-L-A-K-A-T-G-L-I-R-S-E-L-G-S-R-L-S-I-Y-K-T-P-E-L-T-F-E-R-D-N-S-V-Q-Y-G-S-R-I-D-E-L-I-N-N-L-K-R-Q-D"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-K-K-S-T-R-T-T-P-E-D-S-Q-A-S-T-T-D-S-A-A-T-S-T-A-S-E-A-T-Q-A-A-T-S-A-T-D-D-Q-A-E-Q-T-T-A-V-D-P-T-Q-Q-I-T-D-L-K-A-Q-L-D-A-K-D-D-Q-L-L-R-A-Q-A-E-I-V-N-M-Q-N-R-N-K-K-E-Q-A-A-L-L-K-Y-D-G-Q-A-L-A-K-D-V-L-P-V-L-D-N-L-E-R-A-L-A-T-P-A-D-D-E-A-A-Q-Q-L-K-K-G-V-E-M-V-Y-G-H-L-Q-D-A-L-K-K-H-G-V-T-E-V-A-A-A-G-E-K-F-D-P-N-I-H-Q-A-V-Q-T-V-P-V-D-D-D-H-P-A-D-T-V-V-Q-V-L-Q-R-G-Y-L-L-K-D-R-T-L-R-P-A-M-V-V-V-A-Q"} +{"text": "### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-T-M-D-D-T-K-A-T-V-L-S-I-L-A-D-L-T-G-E-D-V-S-S-N-M-D-V-N-L-F-D-E-G-I-L-D-S-M-G-S-V-Q-L-L-L-E-L-Q-N-Q-L-G-I-E-V-P-V-S-E-F-Q-R-S-E-W-D-T-P-A-K-I-V-A-K-V-E-N-L-Q"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-D-L-E-L-Y-D-Q-T-T-T-G-A-Q-P-E-Q-L-Q-L-I-R-D-L-I-D-L-A-G-Q-T-L-K-L-R-D-D-T-E-V-S-V-T-L-M-N-N-D-A-I-Q-K-I-N-E-Q-Y-R-G-V-D-R-P-T-D-V-I-S-F-A-M-H-D-D-D-E-D-D-L-I-V-M-D-P-E-M-A-A-E-M-P-L-N-L-G-D-I-M-I-S-V-D-K-V-S-E-Q-A-A-F-L-N-H-S-E-A-R-E-L-G-Y-L-V-V-H-G-F-L-H-L-N-G-Y-D-H-L-Q-P-A-D-E-T-E-M-F-T-L-Q-R-Q-I-L-D-A-Y-G-L-E-K"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-T-N-I-E-Q-I-E-G-L-L-F-V-A-G-D-E-G-I-T-V-A-E-I-E-H-A-T-G-F-A-K-P-A-I-T-T-M-L-T-Q-L-A-T-K-Y-Q-A-D-P-D-S-A-L-M-I-L-S-T-A-N-T-Y-R-L-A-T-K-A-A-V-A-P-V-L-K-R-Y-F-E-A-P-L-T-T-S-L-S-Q-A-S-L-E-V-L-A-I-I-A-Y-R-Q-P-L-T-R-I-E-I-D-E-I-R-G-V-H-S-G-S-T-I-Q-K-L-V-L-R-Q-L-V-T-E-T-G-R-L-S-E-P-G-R-P-I-L-Y-G-T-T-E-L-F-L-D-Y-F-G-L-K-S-L-D-D-L-P-A-I-D-L-A-A-L-S-D-A-E-H-P-A-P-E-T-D-L-F-L-N-A-F-Q-D-K-L-Q-A-E-R-E-D-E"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-A-K-R-N-F-T-P-K-D-I-L-Q-K-E-F-K-P-K-M-R-G-Y-D-P-A-D-V-D-G-F-L-D-N-V-I-K-D-Y-E-S-F-T-K-D-N-Q-Q-L-S-D-E-N-E-R-L-R-A-K-V-D-E-L-T-K-Q-V-A-V-G-A-T-S-P-S-S-Q-P-T-S-T-V-T-N-M-D-I-L-K-R-L-S-N-L-E-R-H-V-F-G-A-Q-L-D-N-N-Q-N-E-S-H-R-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-R-Q-N-Q-L-I-E-K-I-T-N-E-Q-L-R-T-D-I-P-D-F-R-A-G-D-T-V-R-V-H-A-R-V-V-E-G-T-R-E-R-I-Q-L-F-E-G-V-V-I-K-R-H-G-S-G-I-S-E-T-Y-T-V-R-K-I-S-N-G-V-G-V-E-R-T-F-P-L-H-T-P-R-V-A-A-I-D-V-V-R-Q-G-R-V-R-R-A-K-L-Y-Y-L-R-N-L-H-G-K-A-A-R-I-P-E-R-R-R-G"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-D-Y-Y-R-V-G-T-L-V-N-T-H-G-I-R-G-E-V-K-V-V-V-V-T-D-F-P-E-E-R-F-K-V-G-Q-Q-L-S-L-F-K-T-P-D-E-T-T-G-G-I-T-V-K-I-A-K-A-R-E-Q-K-G-L-Y-F-L-T-F-E-G-L-D-N-I-N-D-V-E-R-Y-K-G-W-T-I-K-V-P-A-E-A-L-H-A-L-P-A-G-E-Y-Y-Y-H-Q-I-V-G-L-Q-V-V-T-T-A-D-E-P-L-G-T-I-K-E-I-L-S-P-G-A-N-D-V-W-V-V-K-R-D-H-G-Q-S-D-V-L-L-P-K-I-P-Q-V-I-K-D-V-D-L-D-A-G-V-V-T-V-E-L-M-E-G-L-I-D"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-I-L-Y-P-S-V-D-D-L-L-K-Q-V-N-S-R-Y-S-L-I-M-L-A-S-K-R-A-H-E-L-D-A-G-A-A-P-M-L-S-E-Y-K-S-V-K-T-I-G-R-A-M-E-E-I-A-A-G-D-L-M-I-D-P-D-E-T-D-K-D"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-E-Q-P-T-F-E-Q-N-L-S-Q-L-E-T-I-V-N-Q-L-E-Q-G-D-V-P-L-E-Q-A-L-D-Q-F-Q-K-G-V-A-L-S-K-Q-L-Q-A-T-L-E-G-A-E-K-T-L-T-K-M-M-N-E-N-G-D-E-V-P-F-E-Q-A-D-A-N-E"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-L-T-R-H-E-I-R-E-K-A-F-Q-A-L-F-A-L-N-A-N-P-D-A-D-E-N-Q-L-F-Q-Q-L-L-N-P-E-E-T-D-A-V-E-I-P-A-Y-L-S-T-L-V-T-G-V-R-E-H-Q-V-E-L-D-A-Q-I-Q-P-Y-L-S-Q-K-W-S-L-D-R-L-A-K-T-D-L-I-I-L-R-I-A-F-F-E-L-Q-F-V-D-D-V-P-T-K-V-A-V-N-E-A-I-E-L-T-K-A-F-S-D-D-R-S-R-K-F-V-S-G-V-L-G-K-V-V-K-N-Q-A-N"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-T-A-D-F-K-N-G-L-T-I-E-V-D-N-A-I-W-R-I-V-E-F-Q-H-V-K-P-G-K-G-G-A-F-V-R-S-K-L-K-N-L-R-T-G-A-V-Q-D-K-T-F-R-A-G-A-R-M-E-Q-A-P-I-E-K-S-T-M-Q-Y-L-Y-A-D-G-D-S-Y-V-F-M-N-T-E-T-Y-E-Q-I-E-I-P-G-D-H-I-Q-D-E-L-K-F-L-K-E-N-M-E-V-Q-V-T-L-Y-K-G-E-V-L-G-I-D-L-P-N-T-V-T-L-E-V-A-E-T-E-P-G-I-K-G-D-T-A-S-G-G-S-K-P-A-T-L-E-T-G-A-I-I-Q-V-P-F-F-V-K-A-G-D-K-L-I-V-N-T-V-D-S-T-Y-V-S-R-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-V-T-G-G-K-Q-Y-K-V-E-A-G-Q-A-I-Y-V-E-K-L-D-A-A-A-G-D-K-V-T-F-D-Q-V-V-F-V-G-G-D-T-T-K-V-G-T-P-T-V-D-G-A-T-V-E-G-T-V-E-K-Q-G-R-D-R-K-V-V-T-F-K-Y-K-A-K-K-G-Q-H-T-K-K-G-H-R-Q-P-Y-T-K-V-T-I-D-T-I-N-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-E-D-K-T-Y-P-M-T-E-E-G-K-V-K-L-E-K-E-L-E-D-L-R-I-N-Q-R-P-E-I-I-N-R-I-K-I-A-R-S-Y-G-D-L-S-E-N-S-E-Y-E-S-A-K-N-E-Q-S-L-L-E-N-R-I-K-T-V-E-H-M-L-Q-Y-A-E-I-I-D-S-D-K-I-D-E-T-E-V-S-V-G-K-I-V-T-F-K-E-L-P-D-E-E-P-E-S-Y-T-I-V-G-A-A-E-A-D-P-M-V-G-K-I-S-N-D-S-P-I-A-K-G-L-I-G-H-H-V-D-E-E-V-A-I-N-I-P-A-G-T-M-T-V-K-I-L-K-V-E-N-A"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-G-G-T-V-T-R-K-R-R-K-R-I-L-K-L-A-K-G-Y-R-G-A-K-H-I-Q-F-K-V-A-K-D-Q-V-M-K-S-Y-L-Y-A-F-R-D-R-R-R-R-K-S-D-F-R-R-L-W-I-A-R-I-N-A-A-A-R-I-N-D-I-S-Y-S-Q-L-M-H-G-L-K-L-A-N-V-D-V-N-R-K-M-L-A-D-L-A-V-N-D-A-D-A-F-K-A-L-V-D-T-A-K-K-A-L-A"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-T-I-A-K-D-S-M-V-N-D-G-I-R-A-R-E-V-R-L-I-A-S-D-G-E-Q-L-G-V-K-S-R-Q-E-A-M-Q-I-A-E-D-A-S-L-D-L-V-L-V-A-P-K-A-K-P-P-V-A-R-I-M-D-Y-G-K-Y-R-F-E-Q-Q-K-K-D-R-E-A-R-K-K-Q-K-V-V-S-I-K-E-V-R-L-S-P-A-I-D-T-N-D-F-N-T-K-L-K-H-A-E-K-F-L-S-K-G-D-K-V-R-V-S-I-R-F-K-G-R-A-I-T-H-K-D-I-G-R-Q-V-L-N-R-M-I-E-A-T-K-E-F-S-T-V-E-A-Y-P-K-M-D-G-R-S-M-F-L-V-L-A-P-K-T-D-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Q-C-P-H-C-H-H-N-G-S-R-V-V-D-S-R-P-T-D-D-G-R-V-I-R-R-R-R-E-C-E-N-C-G-F-R-F-T-T-F-E-R-V-E-A-T-P-L-L-V-I-K-K-N-G-A-R-E-E-F-N-R-E-K-V-L-R-G-I-I-R-S-A-E-K-R-P-V-S-M-E-T-M-T-G-V-V-D-D-V-E-N-K-V-R-S-L-G-E-N-E-I-S-S-Q-V-I-G-E-Y-V-M-E-Q-L-A-D-I-D-E-I-S-Y-I-R-F-A-S-V-Y-R-Q-F-K-D-M-H-V-F-L-N-E-L-Q-D-M-M-E-R-D-K-V-K-L-A-K-P-S-A-K-T-T-H-A-P-K-R-K-K-D"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-T-F-N-G-K-I-N-G-N-G-L-K-I-G-I-A-V-A-R-F-N-A-F-V-T-Q-Q-L-L-T-G-A-Q-E-S-L-V-Q-H-G-V-N-E-T-D-I-D-V-A-W-V-P-G-A-F-E-I-P-L-T-V-Q-K-M-I-T-T-K-R-Y-D-G-V-I-A-L-G-A-V-I-R-G-A-T-A-H-F-D-Y-V-C-S-G-V-T-T-G-I-A-T-V-S-L-A-T-D-T-P-I-M-F-G-V-L-T-T-D-T-I-E-Q-A-M-D-R-A-G-F-K-S-G-N-K-G-A-D-C-A-V-S-L-L-E-T-L-D-V-Q-R-A-I-L-K-A-D-L-A"} +{"text": "### FUNCTION Regulates the transcription of the arc operon, involved in arginine catabolism ### SEQUENCE -M-K-K-S-E-R-Q-A-V-I-E-Q-L-I-S-E-Y-P-I-A-T-Q-E-E-L-M-A-K-L-K-A-E-G-I-A-A-T-Q-A-T-I-S-R-D-I-R-E-M-Q-I-V-K-T-P-D-E-H-G-Q-T-R-Y-A-I-F-K-T-T-N-K-N-E-Q-D-R-L-F-E-T-L-H-D-V-V-T-S-I-D-R-V-E-F-M-N-I-I-H-T-L-P-S-N-G-N-L-L-A-A-I-I-D-D-L-N-L-P-E-V-S-G-T-L-A-G-H-D-T-I-F-V-V-S-P-N-T-T-V-A-K-Q-L-Y-E-S-F-A-S-H-I-S-N-E-D"} +{"text": "### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-I-M-D-D-V-K-A-T-V-L-S-I-L-Q-D-L-T-G-E-D-V-S-N-N-M-D-A-N-L-F-D-E-G-I-L-D-S-M-G-S-V-Q-L-L-L-E-L-Q-N-Q-L-G-I-E-V-P-V-S-E-F-E-R-S-E-W-E-T-P-A-K-I-V-A-K-V-A-S-L-Q"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-I-K-E-F-K-E-F-I-A-R-G-N-V-I-D-L-A-V-G-V-I-I-G-S-A-F-T-A-I-V-K-S-L-T-D-N-L-I-N-P-L-I-G-I-F-L-G-K-V-D-L-S-N-L-K-F-S-I-G-D-A-T-F-K-Y-G-S-F-L-N-A-I-I-N-F-F-I-V-A-I-V-V-F-I-L-V-K-I-I-N-K-V-V-K-N-E-P-E-E-P-E-E-E-E-V-D-V-S-A-Q-Y-L-E-E-I-R-D-L-L-K-E-Q-A-K-K"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-A-E-E-R-I-N-A-E-Q-V-Q-H-V-A-S-L-A-K-L-E-F-T-P-D-Q-L-A-M-F-T-P-Q-L-E-K-I-I-G-M-F-E-E-L-S-T-V-D-T-T-G-V-P-V-T-S-R-M-S-D-H-T-N-T-L-R-E-D-V-A-V-K-S-D-E-A-L-R-E-A-L-L-K-N-A-P-E-T-A-N-G-L-I-K-V-P-A-I-I-D-E-S-G-D-G-E"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-E-I-K-T-T-A-V-A-G-T-L-E-S-S-D-I-Q-I-M-L-M-A-G-D-N-G-I-Q-I-D-L-E-S-D-V-I-K-Q-F-G-A-Q-I-K-H-V-I-T-T-T-L-Q-Q-L-N-I-D-N-V-K-V-R-A-V-D-K-G-A-L-D-C-V-I-K-A-R-T-I-T-A-A-Q-R-A-L-E-T-T-T-P-A-W-E-V-L"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-Y-M-A-K-P-G-E-I-D-R-K-W-Y-V-V-D-A-T-D-V-P-L-G-R-L-S-T-V-V-A-S-I-L-R-G-K-N-K-P-T-F-T-P-N-V-D-T-G-D-N-V-I-V-I-N-A-S-K-V-A-L-T-G-K-K-A-E-R-K-I-Y-Y-H-H-T-A-Y-A-G-G-L-K-E-R-T-A-G-D-F-L-A-K-E-P-T-K-L-I-E-T-S-V-K-G-M-L-P-H-N-S-L-G-H-K-M-G-L-K-L-H-V-Y-A-G-A-E-H-T-Q-Q-A-Q-K-P-E-V-L-D-I-T-N-L-I"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-T-R-K-T-T-R-R-R-R-V-K-K-N-I-E-S-G-V-A-H-I-H-S-T-F-N-N-T-L-V-M-I-T-D-M-Q-G-N-A-I-A-W-S-S-A-G-S-L-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-A-A-A-K-A-S-M-E-H-G-M-K-T-V-E-V-A-V-K-G-P-G-S-G-R-E-A-A-I-R-A-L-Q-A-T-G-L-E-V-S-A-I-R-D-V-T-P-V-P-H-N-G-S-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-E-G-I-D-L-P-R-D-K-R-I-V-I-G-L-T-Y-I-Y-G-I-G-N-T-S-A-Q-K-I-L-A-E-A-G-V-S-E-D-V-R-V-R-D-L-T-P-D-Q-E-D-K-I-R-A-V-V-D-G-Y-K-T-E-G-D-L-R-R-E-V-S-L-N-I-K-L-L-Q-E-I-G-S-Y-R-G-M-R-H-R-R-G-L-P-V-R-G-Q-H-T-K-N-N-A-R-T-R-K-G-K-K-V-S-I-A-G-R-K-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-D-V-I-E-I-Q-G-T-I-K-E-T-L-P-N-A-M-F-K-V-E-L-E-N-G-A-E-I-L-A-H-V-S-G-K-I-R-M-H-Y-I-R-I-L-P-G-D-K-V-T-V-E-M-S-P-Y-D-L-T-K-G-R-I-T-Y-R-F-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-T-P-S-E-G-S-R-F-S-R-R-R-I-G-R-G-D-S-S-G-Q-G-K-T-S-G-R-G-Q-K-G-Q-K-A-R-G-K-V-R-V-G-F-E-G-G-Q-M-P-L-Y-R-R-I-P-K-R-G-F-T-N-I-N-R-K-E-Y-A-V-V-N-L-D-G-L-N-R-F-D-D-G-A-E-V-T-P-E-S-L-K-E-A-G-L-V-K-K-S-S-A-V-K-V-L-G-N-G-K-L-N-K-K-L-T-V-K-A-S-K-F-S-A-T-A-V-A-A-I-E-A-A-G-G-K-T-E-V-I"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-T-F-I-D-P-S-K-L-D-L-D-D-N-V-V-A-I-N-R-I-T-K-V-V-K-G-G-R-R-L-R-F-A-A-L-V-I-V-G-D-H-K-G-H-V-G-F-G-T-G-K-A-Q-E-V-P-E-A-I-R-K-A-S-E-A-A-K-K-N-L-I-T-V-P-M-V-G-T-T-I-P-H-E-A-L-G-V-Y-G-G-G-R-I-M-L-K-P-A-V-E-G-S-G-V-A-A-G-G-A-V-R-A-V-M-E-L-A-G-V-D-D-V-T-S-K-R-L-G-S-N-T-P-V-N-V-V-R-A-T-F-E-G-L-K-S-L-K-T-A-E-Q-V-A-A-L-R-G-V-S-A-E-H-L-A-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-T-R-Q-R-R-H-A-R-V-R-G-K-I-S-G-T-A-E-R-P-R-L-N-V-Y-R-S-N-K-N-I-Y-A-Q-V-I-D-D-V-E-G-V-T-L-A-S-A-S-T-L-D-S-E-V-K-G-N-N-K-T-E-K-A-A-S-V-G-E-V-V-A-K-R-A-A-E-K-K-I-V-D-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-Q-A-L-A-E-A-A-R-E-N-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-Y-K-V-I-E-L-P-A-G-V-E-V-S-Q-A-G-E-V-V-T-V-K-G-P-K-G-T-L-T-R-N-I-A-S-D-I-T-M-T-V-E-G-N-E-V-K-F-T-R-P-S-D-D-Y-K-M-K-A-L-H-G-T-T-R-A-N-V-N-N-M-V-E-G-V-T-K-G-F-T-K-N-L-Q-L-V-G-V-G-Y-R-A-Q-L-Q-G-K-K-L-V-L-S-V-G-Y-S-H-P-V-E-F-A-T-P-E-N-L-T-V-E-V-P-D-N-T-H-I-N-I-S-G-I-G-K-Q-A-V-G-D-F-A-A-E-V-R-A-V-R-S-P-E-P-Y-K-G-K-G-I-R-Y-V-D-E-Y-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-M-T-D-P-I-A-D-F-L-T-R-I-R-N-A-N-M-V-R-H-D-S-L-E-V-P-A-S-K-I-K-R-N-I-A-E-I-L-K-N-E-G-F-V-R-D-V-E-Y-I-D-D-D-K-Q-G-I-I-R-V-F-L-K-Y-G-K-D-N-E-R-V-I-S-G-L-K-R-I-S-K-P-G-L-R-S-Y-V-K-A-D-A-V-P-K-V-L-N-G-L-G-I-A-I-I-S-T-S-E-G-V-I-T-D-K-E-A-R-A-K-K-L-G-G-E-V-L-A-Y-V-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-Q-I-A-K-Q-K-R-G-A-K-F-N-V-Q-N-Y-T-R-C-E-R-C-G-R-P-H-S-V-Y-R-K-F-H-L-C-R-I-C-L-R-D-L-A-H-K-G-Q-I-P-G-M-K-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-E-N-R-L-K-A-Q-Y-E-K-E-I-V-P-A-L-V-D-K-F-N-Y-T-S-V-M-Q-V-P-K-L-A-K-I-V-L-N-M-G-V-G-D-A-V-T-N-A-K-N-L-D-E-A-V-E-E-L-T-L-I-S-G-Q-K-P-L-V-T-R-A-K-K-S-I-A-G-F-R-L-R-E-G-M-A-I-G-A-K-V-D-L-R-G-E-R-M-Y-D-F-L-D-K-L-I-N-V-S-L-P-R-V-R-D-F-H-G-V-S-T-R-S-F-D-G-R-G-N-Y-T-L-G-V-R-E-Q-L-I-F-P-E-I-N-Y-D-N-V-N-R-V-R-G-L-D-I-V-I-V-T-T-A-D-S-D-E-E-S-R-E-L-L-T-Q-F-G-M-P-F-A-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-L-I-K-T-G-D-K-V-R-V-I-S-G-K-D-R-G-Q-E-G-T-V-K-K-V-I-S-A-K-N-R-I-V-V-E-G-V-N-K-I-K-K-H-Q-K-P-T-N-V-N-P-Q-G-G-I-V-D-I-E-A-P-I-D-A-S-N-V-M-Y-L-D-P-S-T-N-E-P-T-R-L-G-V-R-R-E-D-G-K-R-V-R-Y-A-K-K-S-G-K-D-L-E-N"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-S-G-A-R-E-I-L-T-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-V-I-V-A-T-V-K-Q-A-T-P-G-G-V-V-K-A-H-D-V-V-K-A-V-I-V-R-T-K-S-G-V-H-R-A-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-R-D-D-K-T-P-Q-G-T-R-I-F-G-P-V-A-R-E-L-R-D-K-D-F-M-R-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-D-T-R-N-S-R-K-V-I-Q-G-R-V-V-S-D-K-M-D-K-T-I-V-V-I-V-E-T-Y-K-N-H-P-V-Y-G-K-R-V-R-Y-S-K-K-F-K-A-H-D-E-K-N-E-A-K-T-G-D-I-V-K-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-I-E-V-V-Q-K-A-V-I-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-Y-R-R-V-H-R-G-K-M-R-G-E-A-K-G-G-K-T-V-A-F-G-D-Y-G-L-Q-T-L-E-S-H-W-I-S-N-R-Q-I-E-A-A-R-V-A-M-N-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-E-K-G-V-G-V-R-M-G-N-G-K-G-T-P-A-G-W-V-A-P-V-K-R-N-K-I-M-F-E-V-A-G-V-P-E-E-V-A-R-E-A-L-R-L-A-G-T-K-L-P-V-K-T-K-I-V-K-R-E-E-V-G-G-E-S-D-E-G"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-E-Q-V-T-S-A-R-A-T-A-K-T-V-R-I-A-A-R-K-V-R-L-V-V-D-L-I-R-G-K-S-V-A-E-A-L-A-I-L-K-F-T-P-R-G-A-S-P-V-V-E-K-V-L-L-S-A-V-A-N-A-E-N-N-F-D-L-D-R-E-D-L-V-V-S-E-A-F-V-N-E-G-P-T-L-K-R-F-R-P-R-A-K-G-S-A-S-P-I-N-K-R-T-S-H-I-T-I-T-V-T-E-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-A-D-A-H-L-L-K-K-I-D-A-Q-S-D-S-D-K-K-S-V-I-K-T-W-S-R-R-S-T-I-F-P-S-F-I-G-Y-T-I-A-V-Y-D-G-R-K-H-V-P-V-Y-I-Q-D-D-M-V-G-H-K-L-G-E-F-V-P-T-R-T-F-H-G-H-G-T-D-D-K-K-T-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-E-A-R-D-V-I-L-R-P-V-V-T-E-S-S-M-A-D-L-D-D-K-R-Y-T-F-D-V-N-V-Q-A-T-K-T-Q-V-K-K-A-I-E-E-I-F-D-V-K-V-V-K-V-N-V-M-N-V-K-G-K-L-K-R-Q-G-R-Y-A-G-Y-T-K-K-R-R-K-A-I-V-T-L-S-S-D-S-N-E-I-K-L-F-N-D-D-Q-Q"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-K-Q-K-I-R-I-R-L-K-A-Y-E-H-R-I-L-D-Q-S-A-D-K-I-V-E-T-A-K-R-T-G-A-T-I-S-G-P-I-P-L-P-T-E-R-T-I-Y-T-V-L-R-S-P-H-K-F-K-D-S-R-E-Q-F-E-M-R-T-H-K-R-L-I-D-I-V-N-P-T-P-K-T-V-D-S-L-M-K-L-D-L-P-S-G-V-D-I-E-I-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-A-P-A-K-R-E-V-L-A-D-P-M-Y-N-S-K-L-V-T-R-L-I-N-H-L-M-L-D-G-K-R-G-T-A-S-T-I-L-Y-D-A-F-D-Q-I-K-E-Q-T-G-N-D-P-L-E-V-F-E-E-A-M-K-N-V-M-P-V-L-E-V-K-A-R-R-V-G-G-S-N-Y-Q-V-P-I-E-V-R-P-D-R-K-T-T-L-G-L-R-W-I-V-Q-Y-A-R-S-R-G-E-H-T-M-S-D-R-L-A-R-E-I-M-D-A-A-N-N-T-G-A-S-V-K-K-R-E-D-T-H-R-M-A-E-A-N-R-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-I-R-K-G-R-K-S-K-V-S-K-S-N-A-P-A-L-N-F-G-Y-N-S-Y-K-K-V-A-T-N-N-P-A-P-Q-K-R-G-V-A-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-Y-A-R-V-R-L-S-N-L-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-V-I-R-G-A-L-D-T-A-G-V-E-D-R-R-Q-S-R-S-K-Y-G-T-K-K-P-K-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-Q-H-G-K-H-P-D-T-A-L-A-Q-N-R-K-A-R-H-D-Y-A-V-E-E-T-Y-E-A-G-I-A-L-T-G-T-E-I-K-S-V-R-D-R-R-V-N-L-K-D-G-F-V-Q-V-R-N-G-E-A-W-M-Q-N-V-H-I-S-P-F-K-E-G-N-R-Y-N-V-D-P-L-R-S-R-K-L-L-L-H-K-K-E-I-S-K-L-G-A-A-T-M-T-K-G-V-T-I-I-P-L-K-M-Y-L-K-H-G-F-A-K-V-L-I-G-V-A-H-G-K-R-E-Y-D-K-R-Q-D-I-K-K-R-E-Q-Q-R-Q-I-D-R-V-M-K-H-Y"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-Y-P-V-P-T-V-I-E-Q-S-S-R-G-E-R-A-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-S-G-P-I-E-D-N-M-A-N-A-I-I-A-Q-L-L-F-L-D-A-Q-D-S-G-K-D-I-Y-L-Y-I-N-S-P-G-G-V-V-T-A-G-L-A-I-Y-D-T-M-N-F-I-K-S-D-V-Q-T-I-V-M-G-M-A-A-S-M-A-S-V-L-A-S-S-G-T-K-G-K-R-F-A-L-P-N-S-E-I-L-I-H-Q-P-S-G-G-A-Q-G-Q-Q-T-E-I-E-I-V-A-E-E-I-L-K-T-R-K-K-I-N-Q-I-L-A-D-N-S-G-Q-S-V-E-K-L-N-H-D-T-E-R-D-N-Y-L-S-A-Q-E-A-K-D-Y-G-L-I-D-D-I-M-E-N-N-K-L-K"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-A-K-V-E-S-F-T-L-D-H-T-K-V-L-A-P-Y-V-R-K-I-T-V-E-N-G-P-K-G-D-A-I-T-N-F-D-L-R-L-V-Q-P-N-K-T-A-I-D-T-A-G-L-H-T-I-E-H-M-L-A-G-L-L-R-D-R-M-D-G-V-I-D-C-S-P-F-G-C-R-T-G-F-H-L-I-T-W-G-E-H-D-T-V-E-V-A-K-A-L-K-S-S-L-E-F-I-A-G-P-A-K-W-E-D-V-Q-G-T-T-I-D-S-C-G-N-Y-K-D-H-S-L-F-S-A-K-E-W-A-K-L-I-L-S-Q-G-I-S-S-D-P-F-V-R-K-V-V-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-I-L-Q-Q-Q-E-E-E-E-Q-T-I-G-G-I-V-I-A-N-N-A-K-E-K-P-Q-S-G-K-V-V-A-V-N-D-G-R-V-L-D-N-G-T-K-V-D-P-S-V-K-V-G-D-Q-V-L-F-D-K-Y-A-G-T-E-V-K-Y-Q-G-A-K-Y-L-V-L-H-E-K-D-I-V-A-I-E-D"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Q-Y-P-E-P-I-A-K-L-I-D-S-Y-M-K-L-P-G-I-G-G-K-T-A-T-R-L-A-F-Y-T-I-D-M-N-G-D-D-V-T-E-F-A-K-S-L-I-A-A-K-R-D-L-H-F-C-S-I-C-G-N-I-T-E-D-D-P-C-V-I-C-K-D-K-S-R-D-Q-S-T-V-L-V-V-E-E-A-K-D-V-M-A-M-E-K-I-K-E-Y-N-G-L-Y-H-V-L-H-G-V-L-S-P-I-D-G-K-G-P-E-D-I-N-I-A-S-L-L-K-R-L-Q-Q-N-E-A-I-K-E-V-I-I-A-T-N-A-T-P-E-G-E-A-T-A-M-Y-I-S-R-L-V-K-P-A-G-I-K-V-T-R-L-A-H-G-L-S-V-G-S-D-I-Q-Y-A-D-E-M-T-L-F-K-A-V-E-G-R-Q-E-M"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-R-G-M-G-N-M-Q-S-M-M-K-Q-M-K-K-M-Q-A-Q-M-T-A-E-Q-A-A-L-N-E-Q-T-F-T-G-A-A-P-D-D-M-V-K-V-T-F-T-G-D-K-K-M-K-D-I-T-I-N-P-D-A-V-D-P-D-D-V-D-M-L-Q-D-L-V-V-A-A-V-N-D-A-L-T-K-V-D-E-Q-T-Q-S-T-M-G-K-Y-T-K-G-L-Q"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-F-D-K-D-A-I-I-D-S-L-K-E-A-S-I-S-D-L-N-D-L-V-K-A-I-E-E-E-F-D-V-S-A-S-A-P-V-A-V-A-G-A-A-G-G-D-A-A-A-A-K-D-S-Y-D-V-E-L-T-E-S-G-D-Q-K-V-K-A-I-K-A-V-R-D-I-T-G-L-G-L-K-D-A-K-G-L-V-D-N-V-P-S-I-I-K-E-G-V-S-E-D-E-A-N-D-M-K-A-K-L-E-E-V-G-G-V-V-T-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-K-E-T-I-A-V-K-A-Q-E-V-E-E-V-A-E-Q-L-K-S-S-V-S-A-I-V-V-D-Y-R-G-L-T-V-E-Q-V-T-D-L-R-K-Q-L-R-E-A-G-V-K-M-R-V-I-K-N-K-I-M-V-R-A-A-D-K-A-G-F-E-D-L-K-P-V-F-A-G-P-T-A-V-A-F-S-E-E-D-P-V-A-P-A-K-I-L-A-N-F-A-K-T-A-D-A-L-Q-L-K-G-G-V-I-E-G-K-V-A-D-L-E-T-V-Q-E-Y-A-T-M-P-S-R-E-E-L-L-A-T-I-A-N-L-L-Q-A-P-V-R-N-V-A-Y-A-V-K-A-V-A-E-K-G-D-E-D-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-A-N-V-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-I-N-I-M-G-F-T-K-D-F-N-A-R-T-A-D-Q-A-G-M-I-I-P-V-V-I-T-V-Y-E-D-R-S-F-D-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-E-S-G-S-G-E-P-N-T-K-K-V-A-T-V-T-K-D-Q-V-K-Q-I-A-E-T-K-M-Q-D-L-N-A-A-D-V-E-A-A-M-R-M-I-E-G-T-A-R-S-M-G-F-T-V-E-G"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-M-I-V-G-L-G-N-I-G-R-Q-Y-A-Q-T-R-H-N-V-G-F-M-I-V-D-E-L-A-S-K-L-N-V-T-F-Q-T-S-K-F-E-A-Q-V-A-T-A-F-Q-D-G-E-K-I-L-L-V-K-P-A-T-Y-M-N-D-S-G-R-A-V-G-P-L-M-S-Y-Y-N-V-D-P-A-D-L-L-V-I-H-D-D-L-D-L-P-L-G-K-V-R-L-K-Q-K-G-S-A-G-G-H-N-G-I-K-S-I-I-S-H-V-G-D-Q-H-F-K-R-V-K-V-G-I-D-H-P-Q-K-M-S-V-V-D-Y-V-L-G-K-F-T-P-A-E-V-A-K-F-D-D-A-K-I-T-A-L-A-A-V-E-A-W-L-A-N-D-D-F-T-A-V-M-N-Q-Y-N"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-Y-G-T-G-I-D-L-T-E-L-S-R-I-E-A-I-L-A-K-G-L-R-L-P-E-K-I-L-T-P-A-E-L-A-V-F-S-R-Y-P-V-K-R-Q-I-E-F-M-A-G-R-F-S-A-K-E-A-Y-S-K-A-Y-G-T-G-I-G-A-A-V-G-F-Q-D-I-E-I-L-D-N-A-Q-G-K-P-E-V-T-R-H-P-F-D-G-P-A-W-I-S-I-S-H-T-D-T-L-V-M-T-Q-V-I-L-E-R-G-N-L"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-E-L-K-Q-F-D-G-Q-K-K-S-E-L-S-L-I-E-V-A-H-A-I-L-S-Q-H-G-D-V-M-A-F-A-D-L-T-N-A-V-Q-S-Y-L-G-K-S-D-E-E-I-R-E-R-L-S-Q-F-Y-T-D-L-N-I-D-G-S-F-I-S-L-G-D-N-M-W-G-L-R-A-W-Y-P-F-E-S-I-D-E-A-V-I-H-T-D-D-D-E-D-E-D-R-P-K-R-K-K-V-N-A-F-L-A-D-A-G-D-D-D-D-V-I-D-Y-D-D-D-D-P-E-D-D-D-N-Y-D-D-D-D-D-Q-D-D-D-T-D-D-S-A-S-S-K-Y-D-E-L-A-G-V-D-D-T-D-D-D-V-A-D-E-T-L-P-D-G-I-E-G-Q-L-S-E-L-N-D-D-D-D-D-D-D-Y-D-D-E-D-D-E-S-K"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-E-P-T-F-N-K-M-T-A-A-G-Y-H-A-I-E-Q-E-I-E-D-L-K-Q-Q-R-P-E-R-I-R-I-L-A-A-A-A-A-L-G-D-R-S-E-N-A-E-Y-S-S-A-K-R-D-L-G-R-L-E-S-R-L-R-Y-L-N-K-Q-L-Q-Y-A-Q-I-V-Q-P-A-D-N-D-Q-L-D-I-G-K-F-V-T-I-E-F-L-D-D-H-D-Q-I-T-Y-Q-L-V-G-K-Q-E-A-N-L-E-Q-Q-K-I-S-F-T-S-P-I-G-Q-A-L-A-N-H-T-V-D-D-V-V-T-V-N-A-P-N-G-A-Y-Q-V-K-V-I-A-V-K-R-A"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-K-K-I-I-A-I-T-G-F-A-M-L-G-G-G-L-R-E-G-L-S-L-L-V-T-W-P-Q-H-F-W-I-T-C-L-I-N-I-V-G-A-F-V-L-S-L-I-T-N-L-L-P-A-R-L-P-V-S-E-D-I-V-I-G-M-S-V-G-F-V-G-S-F-T-T-F-S-T-F-T-F-E-T-L-Q-S-F-Q-S-G-H-S-V-L-A-L-S-Y-V-A-A-S-L-G-L-G-L-L-A-G-L-A-G-N-F-L-S-T-Y-W-L-P-K-E-E-F"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-V-L-V-G-L-A-G-A-G-A-A-V-G-A-L-S-R-Y-G-I-M-R-L-A-L-P-L-N-R-W-P-L-P-I-A-T-L-F-I-N-L-T-G-A-L-L-L-G-W-I-L-T-S-S-L-P-P-N-W-Q-I-F-L-G-T-G-I-M-G-G-Y-T-T-F-S-T-M-I-N-E-L-V-L-L-G-R-N-H-H-Q-R-V-A-W-E-Y-F-G-L-S-L-V-G-G-L-V-M-V-Y-L-G-T-L-I"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-N-I-K-I-I-C-V-G-K-L-K-E-K-Y-F-K-Q-G-I-A-E-Y-A-K-R-M-S-K-F-A-K-F-Q-I-V-E-V-P-D-E-K-A-P-E-S-L-S-N-A-E-M-E-N-V-K-A-K-E-G-Q-R-I-L-E-K-I-K-D-R-D-Y-V-Y-A-L-A-I-L-G-K-E-R-S-S-E-E-F-A-A-E-I-D-K-L-T-T-Y-G-H-S-D-I-D-F-V-I-G-G-S-L-G-L-S-P-E-V-L-K-R-A-D-T-Q-I-S-F-G-R-F-T-L-P-H-Q-L-M-R-L-V-L-S-E-Q-V-Y-R-A-F-M-I-N-V-G-S-P-Y-H-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-F-L-N-D-V-R-G-K-G-K-R-G-Q-I-K-N-V-P-D-G-Y-A-Q-N-F-L-I-K-K-G-L-A-K-E-A-T-K-A-A-I-N-T-L-K-A-E-Q-K-S-E-A-A-R-A-A-E-E-L-A-E-A-K-Q-V-K-T-V-L-E-A-D-E-T-V-V-E-L-K-A-K-A-G-T-D-G-R-L-F-G-S-I-P-S-K-Q-I-A-T-A-L-A-D-Q-Y-Q-V-K-L-D-K-R-K-I-E-L-P-E-P-I-R-V-L-G-Y-T-N-V-P-V-K-L-H-P-E-V-T-A-K-I-R-V-H-V-V-E-K"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Q-Q-R-R-G-G-R-R-R-R-K-V-D-F-I-A-A-N-H-I-E-Y-I-D-Y-K-D-T-D-L-L-R-R-F-I-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-N-Q-R-S-L-T-I-A-I-K-R-A-R-I-M-G-L-L-A-F-V-S-E-D"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-R-T-I-L-V-G-R-L-T-R-D-P-E-L-R-Y-T-N-G-G-A-A-V-A-T-F-T-I-A-V-N-R-Q-F-T-N-Q-N-G-E-R-E-A-D-F-I-S-C-V-I-W-R-K-A-A-E-N-F-A-N-F-T-H-K-G-S-L-V-G-I-D-G-R-I-Q-T-R-N-Y-E-N-Q-Q-G-V-R-V-Y-V-T-E-V-V-V-E-N-F-S-L-L-E-S-R-A-E-S-E-R-H-Q-A-A-N-G-G-S-G-N-N-N-Y-N-N-G-N-S-N-Y-N-N-N-N-N-G-Y-S-N-Q-G-Q-N-A-A-P-Q-Q-S-S-A-N-N-N-N-P-F-G-N-G-N-T-G-N-A-S-S-A-A-P-S-S-S-A-N-N-N-N-Q-A-D-P-F-A-N-N-G-D-Q-I-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-E-S-K-K-Y-E-I-T-Y-I-V-R-P-D-I-D-D-A-A-K-T-A-L-V-D-R-F-D-K-I-L-T-D-N-G-A-Q-V-I-D-S-K-D-W-S-K-R-R-F-A-Y-E-I-G-G-F-N-E-G-T-Y-H-I-V-N-L-T-A-T-D-D-A-A-L-N-E-F-D-R-L-S-K-I-N-D-D-I-L-R-H-M-I-V-K-R-E-D"} +{"text": "### FUNCTION Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 ### SEQUENCE -M-R-K-Y-F-L-G-E-E-F-T-K-Q-D-L-K-Q-M-N-P-L-V-L-A-Y-I-G-D-A-V-Y-E-I-F-I-R-T-Y-I-I-S-K-N-K-D-T-C-V-N-K-L-H-K-K-T-I-Q-F-V-K-A-D-A-Q-S-Y-F-I-R-E-I-Q-K-Y-L-N-E-E-E-I-K-V-F-K-R-G-R-N-T-K-S-N-T-S-A-K-N-A-S-I-Q-D-Y-R-M-A-T-G-F-E-T-V-I-G-Y-L-Y-L-L-N-E-D-E-R-L-E-E-I-M-K-L-V-I-N-L-Y-E-E-S-S-Q-N-E-G-E-N-H-G-S-K-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-T-G-M-I-K-L-Q-L-A-A-G-K-A-S-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-A-F-C-K-E-F-N-E-K-T-A-K-Q-A-G-L-I-I-P-V-V-I-T-V-Y-Q-D-R-S-F-S-F-I-L-K-T-P-P-A-A-V-L-I-K-K-A-V-G-I-E-S-G-S-G-V-P-N-K-T-K-V-A-K-I-T-K-E-Q-L-K-E-I-A-E-M-K-M-P-D-L-N-A-G-S-V-E-A-A-M-R-M-V-A-G-T-A-R-S-M-G-V-T-V-E-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-R-R-W-H-T-V-S-K-N-R-Q-L-K-E-A-K-V-A-E-I-K-E-K-M-E-K-A-E-C-I-V-L-A-D-Y-Q-G-L-T-V-E-E-A-T-E-L-R-K-K-M-R-E-E-G-V-E-Y-K-V-F-K-N-T-L-S-I-L-A-A-K-E-L-G-Y-E-G-I-T-D-L-F-Q-G-P-I-S-I-A-F-G-Y-E-D-P-T-A-P-A-R-I-L-N-D-F-A-K-D-H-K-K-L-E-L-K-G-G-M-V-Q-G-E-V-Y-D-E-D-K-I-K-A-L-A-A-I-P-P-R-D-V-L-I-A-K-L-L-G-S-F-K-A-P-V-S-N-F-A-Y-L-I-N-A-I-K-E-K-K-E-S-E-E-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-Y-I-G-K-R-D-V-L-P-D-P-M-Y-N-S-K-V-L-T-K-L-I-N-S-L-M-Y-D-G-K-K-G-L-A-Q-K-I-C-Y-D-A-F-D-V-I-Q-N-K-T-G-K-E-P-M-E-V-F-E-E-A-M-N-N-V-M-P-L-L-E-V-K-A-R-R-I-G-G-A-T-Y-Q-V-P-L-E-V-R-P-E-R-R-Q-T-L-G-I-R-W-I-L-I-A-A-R-K-R-G-E-K-Y-M-S-E-R-L-A-G-E-L-M-D-A-A-N-N-L-G-A-A-V-K-K-R-E-E-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-Y"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-I-A-K-Y-V-R-M-S-P-R-K-V-G-V-V-L-D-L-V-R-G-K-D-V-N-E-A-F-A-I-L-N-Y-T-P-R-E-A-A-V-V-I-N-K-V-L-K-S-A-V-A-N-A-E-N-N-L-E-L-D-P-S-R-L-Y-V-A-E-A-Y-A-C-Q-G-P-T-L-K-R-Y-Q-P-H-A-Q-G-R-A-F-R-I-N-K-R-T-S-H-V-T-L-V-V-K-E-R-E"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-H-R-K-V-Q-R-G-R-M-K-G-K-A-T-R-G-N-F-I-A-Y-G-D-Y-G-I-Q-A-T-E-C-G-W-I-T-S-N-Q-I-E-S-A-R-I-A-I-N-R-Y-I-R-R-G-G-K-L-W-I-K-I-F-P-D-K-P-V-T-Q-K-P-A-E-T-R-M-G-S-G-K-G-T-P-E-Y-W-V-A-V-V-K-P-G-R-V-L-F-E-L-T-G-V-D-E-E-T-A-R-E-A-M-R-L-A-A-H-K-L-P-V-K-T-K-F-V-K-K-S-D-F-E-E-V-G-G-E-I-N-E-G"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-Q-T-T-L-K-V-A-D-N-S-G-A-R-G-I-M-C-I-K-V-L-G-G-S-N-R-R-Y-A-N-I-G-D-I-I-V-A-S-V-K-S-A-T-P-G-G-V-V-K-K-G-E-V-V-K-A-V-V-V-R-S-K-K-G-V-R-R-A-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-K-D-D-K-Q-P-K-G-T-R-I-F-G-P-V-A-R-E-L-R-D-K-E-F-N-K-I-L-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-N-K-V-H-V-R-K-Q-D-T-V-M-V-I-S-G-K-D-K-G-K-I-G-E-V-L-R-V-L-P-K-S-G-K-V-V-V-K-D-V-N-V-V-T-K-H-Q-K-P-S-R-E-N-M-Q-G-G-I-I-H-V-E-A-P-I-Y-S-S-K-V-M-L-Y-C-T-K-C-K-S-V-T-R-I-N-H-K-I-L-D-D-G-T-K-V-R-V-C-K-K-C-G-E-T-F"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-V-P-R-L-Q-E-K-Y-E-K-E-V-I-P-A-L-I-E-K-F-G-Y-K-N-I-M-E-V-P-K-L-E-K-I-V-I-N-M-G-V-G-E-A-K-E-N-Q-K-M-L-E-S-A-V-S-D-L-S-I-I-A-G-Q-K-P-I-V-T-K-A-K-K-S-V-A-N-F-K-I-R-E-N-M-P-I-G-C-K-V-T-L-R-K-V-K-M-Y-E-F-A-D-K-L-M-N-V-A-L-P-R-V-R-D-F-R-G-V-S-S-K-S-F-D-G-R-G-N-Y-S-L-G-V-K-E-Q-L-M-F-P-E-I-E-Y-D-K-V-D-K-V-R-G-M-D-I-I-F-V-T-T-A-K-T-D-E-E-A-R-E-L-L-R-F-L-G-M-P-F-A-H"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-L-L-T-R-V-R-N-A-N-I-A-R-H-E-A-V-E-I-P-A-S-N-I-K-K-A-I-A-N-I-M-L-Q-E-G-Y-I-T-D-L-E-E-Y-N-D-G-A-V-P-M-L-K-I-T-M-K-Y-G-Q-N-K-E-R-V-I-T-G-L-K-R-I-S-K-P-G-L-R-V-Y-C-R-K-D-E-V-P-K-V-L-N-G-L-G-T-A-V-I-S-T-S-K-G-I-L-P-D-K-E-A-R-K-L-S-I-G-G-E-V-L-C-Y-I-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-R-L-P-I-A-I-P-N-G-V-T-V-T-V-S-P-E-N-V-V-T-V-K-G-P-K-G-E-L-T-K-T-M-H-P-N-I-D-I-A-I-E-E-N-S-V-I-V-T-R-K-N-D-E-K-Q-N-R-S-L-H-G-L-T-R-S-L-V-N-N-M-V-V-G-V-T-E-G-Y-E-K-K-L-E-L-V-G-V-G-Y-R-A-Q-L-Q-G-K-K-L-V-L-N-L-G-F-S-H-P-V-E-I-E-A-K-E-G-V-E-F-Q-L-D-G-T-N-K-I-T-V-K-G-I-D-K-E-L-V-G-A-V-A-S-D-I-R-S-W-R-K-P-E-P-Y-K-G-K-G-I-K-Y-E-N-E-A-I-R-R-K-E-G-K-T-G-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-F-K-K-Q-S-R-Q-K-G-R-E-K-R-H-L-R-I-R-K-N-I-F-G-T-P-E-M-P-R-L-S-V-Y-R-S-E-K-N-I-Y-A-Q-I-I-D-D-L-N-G-V-T-L-V-A-A-S-S-L-D-K-E-F-D-A-K-G-S-N-K-D-G-A-K-L-V-G-E-L-V-A-K-R-A-I-E-K-G-V-T-K-V-V-F-D-R-G-G-Y-I-Y-H-G-R-V-Q-E-L-A-E-G-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-R-P-A-E-G-S-R-K-S-P-K-R-V-G-R-G-T-G-S-G-L-G-K-T-S-A-R-G-E-N-G-Q-N-S-R-S-G-G-G-V-R-P-G-F-E-G-G-Q-M-P-L-Y-R-R-L-P-K-R-G-F-T-N-I-F-A-K-K-Y-T-A-I-N-I-D-R-L-N-I-F-E-D-D-T-V-V-T-P-E-L-L-I-E-K-G-V-I-S-K-V-Y-D-G-V-K-I-L-G-N-G-E-L-D-K-K-L-I-V-K-A-T-K-F-S-K-A-A-A-E-K-I-E-A-A-G-G-K-V-E-V-I"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-D-L-P-R-E-K-R-V-E-V-G-L-T-Y-I-F-G-I-G-T-S-S-A-K-K-I-L-K-E-T-G-V-N-P-D-I-R-I-K-D-L-S-E-E-E-V-N-L-L-R-D-Y-I-N-Q-N-L-K-V-E-G-D-L-R-R-D-V-A-L-D-I-K-R-L-K-E-I-G-S-Y-R-G-I-R-H-R-R-G-L-P-V-R-G-Q-K-T-K-T-N-A-R-T-R-K-G-P-K-K-L-V-V-S-R-K-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-A-V-S-K-T-K-R-T-R-R-R-K-E-R-K-N-I-E-R-G-C-A-H-I-K-S-T-F-N-N-S-I-V-T-L-T-D-T-A-G-N-A-L-S-W-A-S-A-G-G-L-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-T-A-A-K-A-A-M-E-H-G-L-K-S-V-E-V-Y-V-K-G-P-G-S-G-R-E-A-A-I-R-S-L-Q-A-A-G-L-E-V-T-L-I-K-D-V-T-P-I-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-S-Y-I-A-K-P-E-E-V-Q-R-K-W-Y-V-V-D-A-E-G-K-P-L-G-R-V-A-S-Q-V-A-L-I-L-R-G-K-N-K-P-T-Y-T-P-H-V-D-T-G-D-Y-V-V-I-I-N-A-E-K-V-V-L-T-G-K-K-L-D-Q-K-M-L-R-H-H-S-L-Y-P-G-G-L-K-E-V-P-Y-K-E-A-L-A-K-K-P-E-F-V-F-E-E-A-V-R-R-M-L-P-K-G-P-L-G-R-K-M-L-K-K-L-K-V-Y-R-G-S-E-H-N-N-E-A-Q-N-P-E-V-L-E-L-R-Y"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-L-G-I-G-I-D-I-I-E-I-I-R-I-K-N-A-I-E-R-N-S-K-F-M-K-R-V-F-T-E-K-E-I-K-Y-F-E-K-I-N-F-R-H-E-S-I-A-G-R-F-A-A-K-E-A-I-V-K-A-L-G-T-G-F-R-N-M-K-I-T-D-I-E-V-I-N-D-K-V-G-K-P-L-V-E-L-K-G-G-A-L-E-K-I-K-V-Y-K-D-V-K-I-H-L-S-I-S-H-N-R-D-N-A-I-A-Y-S-I-I-E-G-E-C-I"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-L-T-I-T-S-I-K-D-G-I-V-I-D-H-I-K-S-G-Y-G-I-K-I-F-N-Y-L-N-L-K-N-V-E-Y-S-V-A-L-I-M-N-V-F-S-S-K-L-G-K-K-D-I-I-K-I-A-N-K-E-I-D-I-D-F-T-V-L-G-L-I-D-P-T-I-T-I-N-I-I-E-D-E-K-I-K-E-K-L-N-L-E-L-P-K-K-V-E-D-V-I-R-C-K-N-P-R-C-I-T-S-I-E-K-Y-I-P-H-V-F-Y-L-I-D-K-E-K-V-E-Y-K-C-K-Y-C-D-E-I-Y-K-V-V-E-E"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-V-T-I-E-D-K-I-N-L-F-S-K-I-I-Y-G-E-V-D-D-K-I-N-S-E-L-D-E-L-E-N-V-E-K-D-T-I-E-K-E-E-R-E-V-K-K-Y-R-N-K-N-M-Q-S-V-E-K-K-I-K-S-K-F-E-K-E-V-F-K-L-K-L-E-E-Q-Q-Q-L-L-N-L-K-E-N-M-I-N-E-T-L-E-S-L-K-E-R-I-I-D-F-T-K-S-D-E-Y-I-N-Y-I-K-S-H-L-D-N-T-L-K-D-I-E-N-K-E-G-I-I-I-Y-F-N-K-K-D-L-E-K-F-K-K-V-I-N-K-D-N-V-E-V-S-N-E-S-K-D-I-I-G-G-Y-I-I-Q-D-K-N-N-K-F-R-V-D-C-S-L-E-I-S-I-E-E-C-K-E-K-I-G-I-S-I-T-E-L-F-M"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-N-I-I-K-K-G-F-L-M-N-E-E-I-R-E-K-E-V-R-V-I-A-E-D-G-E-Q-L-G-V-I-P-T-S-E-A-L-K-R-A-E-E-K-E-L-D-L-V-M-I-A-P-T-G-K-P-P-V-C-K-I-M-N-Y-G-K-F-I-Y-E-Q-T-K-K-D-K-E-A-K-K-K-Q-K-V-I-N-V-K-E-I-R-L-S-A-T-I-E-E-H-D-I-G-I-K-A-N-N-A-R-K-F-L-K-A-E-D-K-V-K-V-T-V-R-F-R-G-R-E-M-E-H-S-N-V-V-G-N-K-I-L-K-T-F-L-S-K-V-E-D-V-C-V-V-E-K-P-A-R-L-E-G-K-N-M-T-M-V-L-A-P-R-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-A-M-N-A-R-K-K-H-K-K-I-L-K-L-S-K-G-Y-F-G-G-K-S-R-L-F-K-T-A-N-E-S-V-I-R-A-L-R-N-A-Y-T-G-R-K-L-K-K-R-D-Y-R-K-L-W-I-A-R-I-N-A-A-T-R-A-N-G-L-S-Y-S-R-F-M-N-G-L-K-L-A-G-I-D-M-N-R-K-M-L-S-E-I-A-I-N-D-P-K-A-F-S-E-L-V-E-A-A-K-K-Q-L-N-A"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-D-Y-I-K-G-I-Y-K-G-M-H-K-D-Y-I-T-V-E-N-N-G-I-G-Y-K-I-F-T-S-G-N-T-L-Y-E-T-P-E-K-D-E-E-I-K-L-Y-I-Q-Q-I-P-R-D-D-S-I-N-L-Y-G-F-F-T-E-E-E-R-D-M-F-N-L-L-M-T-I-S-G-V-G-A-K-S-S-L-S-L-L-S-V-T-S-I-N-K-L-K-Y-S-I-V-T-E-D-T-T-L-L-T-R-A-P-G-I-G-R-K-T-A-E-R-I-I-L-E-L-K-D-K-F-K-N-D-D-I-I-S-D-I-D-D-L-D-S-I-S-N-F-Q-L-H-S-A-E-A-L-E-A-L-M-S-L-G-Y-S-Q-K-E-S-E-K-A-L-K-N-V-D-K-E-N-S-L-E-D-I-I-K-A-C-L-K-Y-L-M-G"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-K-D-K-I-R-V-I-Q-G-F-P-K-E-G-I-S-F-K-D-V-T-T-I-L-Q-E-K-E-A-F-K-Y-T-I-D-T-L-V-E-E-L-K-D-K-N-V-D-V-V-V-G-P-E-A-R-G-F-L-F-G-A-P-L-A-Y-A-L-G-A-G-F-V-P-V-R-K-K-G-K-L-P-S-T-T-I-S-S-K-Y-E-L-E-Y-G-S-D-E-L-E-M-H-K-D-S-I-K-P-G-Q-R-V-V-I-A-D-D-L-L-A-T-G-G-T-I-C-S-V-I-E-M-I-E-S-L-G-G-E-I-V-S-I-N-F-L-I-E-L-T-D-L-K-G-R-E-K-L-G-K-Y-D-I-S-S-L-V-Q-Y-D-I"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-V-V-T-G-G-K-Q-Y-K-V-T-E-G-D-V-L-F-V-E-K-L-D-A-E-V-D-A-A-I-E-L-D-N-V-L-A-I-S-K-D-N-G-E-F-V-V-G-K-P-V-V-E-G-A-K-V-T-A-K-V-L-K-Q-G-K-A-K-K-V-V-V-F-K-Y-K-P-K-K-H-Y-R-K-K-Q-G-H-R-Q-P-Y-T-K-I-Q-I-E-K-I-N-A"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-K-K-K-A-I-F-G-G-T-F-D-P-I-H-N-G-H-L-H-I-A-Y-K-A-L-N-R-L-K-L-D-K-I-I-F-I-P-S-G-N-P-P-H-K-H-K-E-C-I-T-D-K-N-I-R-Y-N-M-V-K-Y-A-I-E-Q-E-D-K-F-E-I-S-D-Y-E-V-K-K-K-G-K-S-Y-T-Y-E-T-I-E-H-F-R-K-Y-H-P-N-I-D-L-Y-F-I-A-G-A-D-C-L-M-D-I-H-K-W-K-N-I-D-S-M-M-E-K-A-K-L-V-V-F-S-R-P-G-F-S-M-D-T-I-L-F-Q-K-K-Q-V-E-E-K-F-K-K-D-I-I-F-L-D-I-P-L-L-D-V-S-S-T-E-I-R-E-K-I-K-K-G-E-D-I-K-D-L-I-P-E-K-T-Y-N-I-I-K-K-Y-G-L-Y-R"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-K-W-R-H-D-Y-M-A-E-K-K-V-E-D-L-E-M-D-L-N-E-E-E-L-E-E-S-E-V-N-E-D-K-E-F-E-E-L-D-K-S-E-E-E-N-E-V-E-E-L-I-S-T-L-K-D-E-N-E-K-L-N-N-E-M-E-A-L-K-D-R-L-L-R-T-T-G-E-Y-D-N-Y-R-K-R-T-D-R-E-K-E-G-L-Y-A-S-A-C-E-D-V-L-K-E-I-L-P-V-L-D-N-L-E-R-A-I-L-A-K-G-D-I-E-D-L-K-K-G-V-D-M-T-L-K-Q-F-K-D-S-F-K-N-L-G-V-E-E-I-S-T-E-N-G-F-D-P-N-L-H-D-A-V-M-H-V-E-D-S-Q-Y-G-E-K-E-V-V-E-V-F-L-K-G-Y-K-K-G-D-K-I-I-R-H-S-M-V-K-V-A-N"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-Y-I-D-N-R-Q-N-K-I-K-A-Q-E-D-L-D-K-L-I-N-E-I-I-D-Y-A-L-K-K-E-E-V-D-I-G-Y-E-I-S-V-I-Y-V-D-N-E-I-I-K-E-I-N-N-D-T-R-G-I-N-K-E-T-D-V-L-S-F-P-M-L-E-Y-P-K-G-R-V-F-S-E-S-Y-R-E-Y-S-F-G-V-E-Y-L-N-E-G-N-L-V-L-G-D-I-V-L-S-L-E-K-A-L-E-Q-S-K-E-Y-N-H-S-F-L-R-E-V-C-Y-L-V-V-H-S-V-L-H-L-L-G-Y-D-H-I-D-E-E-E-K-V-I-M-R-K-K-E-E-E-I-L-E-S-F-N-I-S-R-G"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-H-T-M-E-V-K-E-Y-R-V-G-I-A-D-L-N-V-A-K-S-P-D-R-I-I-T-V-G-L-G-S-C-I-G-I-A-L-Y-D-R-I-N-G-V-G-G-L-L-H-I-M-L-P-D-S-T-Q-F-K-N-V-S-N-P-L-K-F-P-D-L-G-I-I-I-M-T-D-K-M-K-E-K-G-A-N-I-R-N-I-K-A-K-I-S-G-G-A-S-M-F-N-F-S-D-K-S-M-V-M-D-I-G-R-R-N-I-E-A-V-R-K-K-L-K-E-L-S-I-P-I-V-A-E-E-V-G-G-N-K-G-R-T-M-T-L-D-T-S-N-G-I-V-Q-I-K-T-V-G-V-G-M-K-E-I"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-K-L-N-T-K-H-H-G-T-I-D-Y-E-E-K-D-I-I-N-F-K-R-G-L-P-G-F-E-H-L-K-K-F-I-V-Y-S-I-E-E-N-N-I-F-S-V-L-Q-S-L-E-E-E-N-I-G-I-P-V-L-S-P-F-T-I-C-S-D-Y-E-V-K-L-T-E-E-Q-I-K-N-L-K-I-K-S-E-E-E-V-W-V-L-N-T-V-T-I-N-S-D-Y-K-E-I-T-T-N-L-R-A-P-I-I-I-N-I-K-E-R-I-G-E-Q-I-I-L-K-N-E-E-Y-K-I-K-Y-P-I-F-Q-E-E-N-K-C"} +{"text": "### FUNCTION Involved in the viral transport within, and between cells ### SEQUENCE -M-D-S-F-G-R-A-P-P-L-W-P-Q-S-A-L-P-R-V-P-G-A-A-P-S-S-S-G-L-P-W-S-R-V-G-E-I-A-I-F-T-F-V-A-V-L-A-L-Y-L-L-W-S-W-V-G-R-D-L-L-L-V-L-K-A-R-R-G-G-T-T-E-E-L-T-F-G-P-R-E-R-H-S-L-P-A-V-A-V-A-R-V-E-N-P-P-C-P-S-G-S-V-E-A-R-P-F-T-G"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-G-K-V-L-N-K-V-M-G-F-L-G-L-E-D-E-Y-E-Y-E-E-Y-Y-E-D-T-D-E-L-E-N-S-N-E-S-A-E-F-E-P-I-I-H-S-N-K-K-Q-G-K-V-V-S-I-H-S-T-S-T-P-K-V-S-I-V-K-P-K-T-Y-D-E-V-V-D-I-C-D-D-L-K-D-G-K-I-V-I-V-N-S-I-E-L-D-P-K-V-G-Q-R-L-V-D-F-V-S-G-A-T-Y-S-L-N-G-T-L-E-E-I-E-K-G-I-Y-I-L-S-P-S-N-V-E-V-D-S-E-L-K-N-Q-L-S-S-K-G-M-F-S-W-N-R"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-A-G-D-L-R-K-G-N-T-F-E-L-D-G-Q-V-Y-T-V-V-D-F-L-H-V-K-P-G-K-G-A-A-F-V-R-T-K-L-R-N-V-L-N-G-G-L-K-E-T-T-F-N-P-T-E-K-F-Q-E-A-V-I-E-R-K-E-M-Q-Y-L-Y-T-D-G-E-L-Y-Y-F-M-D-Q-Q-T-F-E-Q-I-P-L-N-F-E-Q-V-E-G-A-I-K-F-L-K-E-N-M-F-A-I-I-K-F-Y-K-G-E-A-F-S-V-E-A-P-N-F-V-E-L-Q-I-T-H-T-D-P-G-A-K-G-N-T-A-T-N-V-M-K-P-A-T-V-E-T-G-A-V-V-H-V-P-L-F-I-N-E-G-D-S-I-R-I-D-T-R-T-G-E-Y-M-E-R-V"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-R-K-K-S-R-E-M-T-M-Q-L-L-F-E-M-M-I-K-K-E-N-Y-V-E-I-I-N-T-L-K-E-A-L-T-E-E-E-D-I-N-S-I-L-G-E-K-K-E-M-D-E-E-R-I-D-L-D-E-V-D-L-E-Y-L-I-H-T-L-K-G-V-E-E-N-S-K-V-L-D-E-H-I-E-K-Y-L-K-N-W-T-L-N-R-L-A-K-V-D-L-A-I-L-R-L-C-S-Y-E-I-L-F-S-N-E-V-P-D-N-V-A-I-N-E-G-V-E-L-A-K-K-Y-G-D-D-K-S-P-A-F-I-N-A-V-L-D-K-I-A-K-Q-M"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-V-T-R-H-E-K-I-L-E-L-I-E-R-K-D-I-E-T-Q-E-E-L-A-E-E-L-R-K-S-G-I-E-I-T-Q-A-T-V-S-R-D-I-K-E-L-K-L-I-K-V-L-G-E-Q-G-K-Y-K-Y-A-A-I-V-K-N-E-N-D-L-S-D-K-L-A-N-I-F-S-H-S-V-V-S-V-E-N-I-N-N-F-V-V-V-K-T-L-S-G-S-G-N-A-A-A-E-A-I-D-S-L-N-F-K-E-I-A-G-T-I-A-G-D-N-T-I-F-I-M-A-R-T-S-E-Q-A-F-E-I-V-K-K-M-K-R-V-I-R-E-R-G-V"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-K-Q-M-N-Y-I-I-N-E-E-N-E-L-R-F-F-S-I-I-E-S-L-L-F-A-S-G-E-P-L-G-L-K-D-I-S-E-I-I-E-L-N-T-L-D-T-K-E-I-L-Q-K-M-I-R-E-Y-E-I-E-K-R-G-I-K-L-I-E-I-E-K-K-Y-Q-L-V-T-K-E-E-N-S-C-F-I-E-Q-L-L-K-T-N-S-S-Q-S-L-S-Q-A-A-L-E-T-L-S-I-V-A-Y-K-Q-P-V-T-R-V-D-V-D-E-I-R-G-V-K-S-D-R-A-L-Q-T-L-L-Q-K-S-L-I-K-E-T-G-R-L-D-V-P-G-R-P-I-L-Y-S-T-T-E-E-F-L-K-H-F-G-L-E-S-I-K-E-L-P-S-L-E-E-L-L-E-E-F-Q-E-E-D-L"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-Y-R-A-G-R-I-N-E-E-V-K-K-E-I-S-S-I-I-R-M-D-L-K-D-P-R-I-S-A-M-V-S-V-T-K-V-D-V-T-K-D-Q-R-Y-A-K-V-Y-V-S-I-F-G-D-E-K-S-K-E-E-T-L-E-A-L-K-S-S-S-G-F-I-R-R-E-V-G-H-R-I-K-L-R-Y-T-P-E-I-I-I-Q-N-D-D-S-I-E-H-G-M-H-I-D-S-I-L-D-K-I-K-E-N-E-D-H-D-N-K"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-N-N-K-T-F-I-D-N-L-K-E-L-T-E-P-I-V-N-D-L-D-Y-E-L-Y-Y-L-E-F-V-N-E-N-K-E-N-Y-L-R-I-Y-I-D-S-E-S-G-I-G-L-E-D-C-E-K-V-S-R-A-V-S-A-M-L-D-E-K-D-P-I-D-T-S-Y-Y-L-E-V-S-S-P-G-L-E-R-Q-L-Y-D-D-K-H-I-E-D-N-I-G-K-T-A-C-V-R-L-E-S-L-F-N-G-G-R-K-F-E-G-K-L-K-S-F-D-N-E-N-L-T-L-E-I-N-A-E-D-F-K-I-P-R-K-K-I-K-R-I-N-L-I-Y-E-G"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-K-E-I-M-N-T-A-E-D-K-M-S-K-A-L-L-A-L-K-K-D-L-A-S-L-K-A-G-R-A-N-P-A-M-L-D-K-I-E-A-E-Y-Y-G-T-M-T-P-L-S-Q-L-A-N-I-S-V-P-E-A-R-I-L-Q-I-Q-P-W-D-K-S-S-L-K-A-I-E-K-A-I-L-V-S-D-L-G-L-N-P-N-N-D-G-T-I-I-R-L-I-I-P-E-L-T-E-E-T-R-R-N-I-V-K-T-V-K-K-Y-G-E-D-T-K-I-A-I-R-S-V-R-R-D-G-N-D-K-I-K-D-L-K-S-D-M-S-E-D-D-I-K-K-A-E-E-E-I-Q-K-I-T-D-N-Y-V-K-K-V-D-E-M-I-D-I-K-E-K-E-I-M-S-I"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-L-D-V-I-K-A-I-E-A-E-Q-I-R-T-D-L-P-A-F-K-V-G-D-T-V-K-V-H-V-K-I-K-E-G-T-R-E-R-I-Q-V-F-E-G-T-V-I-K-R-Q-N-G-G-L-R-E-T-F-T-V-R-R-L-A-Y-G-V-G-V-E-R-T-F-P-V-N-A-P-T-V-S-K-I-E-I-V-R-K-G-K-V-R-R-A-K-L-F-Y-L-R-D-R-V-G-K-A-A-K-V-K-E-R-R-Y"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-Q-F-L-K-I-G-L-I-I-N-T-H-G-L-K-G-E-L-K-V-N-P-Q-T-D-N-I-D-R-F-K-K-L-K-R-V-Y-I-A-G-E-E-K-Q-V-E-G-C-K-F-L-N-D-K-V-V-L-K-I-Q-G-I-D-G-I-E-I-A-N-K-Y-R-N-K-Y-I-E-V-K-R-E-D-A-V-E-L-P-E-G-R-Y-Y-V-A-D-I-I-G-C-K-V-L-D-E-D-G-N-Y-L-G-K-V-K-E-V-I-H-T-K-N-N-D-V-Y-W-V-E-G-K-K-E-L-L-I-P-V-L-K-T-I-V-V-K-I-D-I-E-N-E-E-I-I-I-K-P-V-K-T-W-L-L-E"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-I-R-N-L-R-F-L-G-D-E-L-L-R-K-K-S-R-R-V-E-K-I-D-D-R-I-Q-A-L-L-D-D-M-L-D-T-M-Y-E-N-N-G-V-G-L-A-A-P-Q-V-G-I-L-K-R-V-V-V-I-D-I-G-E-G-P-L-F-L-I-N-P-E-I-I-E-Q-E-G-S-Y-I-E-Q-E-G-C-L-S-V-P-G-R-Q-G-E-V-E-R-P-Y-R-V-K-V-K-A-Q-N-R-D-G-K-E-I-I-V-E-G-E-E-F-L-A-K-A-L-C-H-E-I-D-H-L-N-G-V-L-F-V-D-K-I-I-D-V-K-G-E"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-E-Y-T-L-K-I-K-L-L-K-E-D-A-K-L-P-Q-Y-A-H-D-N-D-A-G-M-D-L-F-S-T-E-D-K-I-I-N-P-G-K-H-A-L-I-L-T-G-I-S-I-E-L-P-E-N-T-E-A-Q-I-R-P-R-S-G-L-A-L-K-N-G-V-T-V-L-N-T-P-G-T-I-D-A-G-Y-R-G-E-I-G-I-I-L-I-N-H-G-E-K-N-F-Q-V-E-K-G-M-K-I-A-Q-M-V-I-K-P-I-V-K-V-N-I-E-E-V-K-M-L-S-E-S-Q-R-G-K-G-G-F-G-S-T-G-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-Y-C-S-Y-N-E-S-K-V-V-D-S-R-S-T-E-D-S-I-S-I-R-R-R-R-E-C-L-E-C-G-K-R-Y-T-T-Y-E-K-I-E-S-V-P-I-L-V-I-K-K-N-L-N-R-E-Y-F-D-R-D-K-I-V-N-G-M-I-K-A-C-Q-K-R-P-V-S-R-Q-Q-I-E-E-I-V-D-E-I-E-K-K-I-N-N-S-M-I-T-E-V-K-S-E-Y-I-G-E-L-I-M-E-K-L-K-D-I-D-E-V-S-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-I-N-T-F-M-E-E-I-K-K-L-K-D-R-E-L"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-D-P-F-G-S-S-S-V-P-P-C-S-T-S-D-L-P-E-P-K-L-Y-F-V-R-L-S-P-H-A-V-P-P-V-R-A-T-H-G-A-A-G-Y-D-L-F-S-A-Y-D-I-K-V-P-A-R-G-R-A-L-V-P-T-D-L-V-F-Q-F-P-P-G-C-Y-G-R-I-A-P-R-S-G-L-A-A-K-F-F-I-D-V-G-A-G-V-I-D-P-D-Y-R-G-N-V-S-V-V-L-F-N-F-S-E-S-S-F-N-I-R-R-G-D-R-V-A-Q-L-I-L-E-R-I-M-V-P-E-L-S-E-L-T-Q-L-G-E-T-D-R-G-A-S-G-F-G-S-T-G-M-G-A-V-D-R-N-Q-R-S-V-L-E-W-L-T-P-G-S-R"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-L-G-L-D-V-G-D-R-T-I-G-V-A-I-S-D-P-L-G-W-T-A-Q-G-V-K-T-I-K-R-S-N-L-K-N-D-I-K-E-I-E-D-I-C-N-E-Y-K-V-D-K-I-V-S-G-L-P-K-N-M-N-G-T-L-G-P-Q-S-E-K-V-T-E-F-C-D-I-L-K-K-E-L-E-K-E-I-I-M-W-D-E-R-L-T-T-V-A-A-H-K-A-M-I-E-G-D-L-S-R-A-K-R-K-K-I-V-D-K-I-A-A-I-Y-I-L-Q-G-Y-L-D-S-V-Y-N-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-R-L-E-N-L-T-S-K-I-I-K-D-S-E-E-K-A-K-I-I-L-D-E-A-K-R-E-E-E-K-I-M-L-G-Q-K-Q-E-G-E-S-I-K-S-K-I-I-E-K-A-Y-L-E-S-K-N-R-K-E-R-I-I-S-N-S-H-L-F-V-R-N-R-K-L-E-A-K-Q-E-V-I-D-K-V-Y-K-E-A-L-N-K-L-A-K-L-N-K-E-E-Y-L-N-F-I-K-D-S-I-L-A-L-E-I-Y-G-D-E-E-I-I-L-S-Q-D-E-K-Y-I-N-K-E-T-I-E-E-I-N-K-E-L-K-S-K-G-K-K-G-E-I-K-I-S-D-K-K-R-D-F-R-G-G-F-I-L-N-K-D-G-I-E-I-N-N-T-F-E-A-L-I-L-S-L-K-D-D-L-E-P-V-I-I-D-T-L-F-S"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-A-E-I-L-I-A-T-E-R-N-E-K-G-K-T-A-R-K-K-G-F-I-P-G-I-I-Y-G-K-D-R-E-G-Q-S-I-N-F-E-R-G-K-L-I-A-F-L-K-E-K-G-E-K-S-K-M-N-F-Q-L-N-G-E-N-K-Q-G-I-I-K-E-V-G-R-D-A-V-T-S-S-I-I-H-I-D-I-Q-E-V-S-A-L-E-K-V-R-W-T-I-P-I-F-F-E-G-R-E-Q-L-K-K-K-E-L-Y-I-Q-V-Y-L-T-E-V-E-V-E-G-K-A-S-D-I-P-N-N-I-T-L-N-V-G-N-L-E-L-G-E-E-V-K-V-K-D-L-N-I-G-S-N-I-R-I-F-N-E-L-E-N-T-I-A-I-I-S-S-S-Q-N-T-N-K-N-I-E-E-E-D-P-S-E-V-E"} +{"text": "### FUNCTION Plays a role in nuclear translocation of the viral pre-integration complex ### SEQUENCE -M-D-P-R-E-R-V-P-P-G-N-S-G-E-E-T-V-G-E-A-F-E-W-L-E-T-T-L-E-H-L-N-R-V-A-V-N-H-L-P-R-E-L-I-F-Q-V-W-Q-K-S-W-A-Y-W-R-E-E-Q-G-M-S-I-S-Y-T-K-Y-R-Y-L-C-L-M-Q-K-A-M-F-I-H-F-A-K-G-C-G-C-L-R-E-G-H-G-P-G-G-W-R-S-G-P-P-P-P-P-P-P-G-L-A"} +{"text": "### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-D-P-N-T-V-S-S-F-Q-D-I-L-M-R-M-S-K-M-Q-L-G-S-S-S-E-D-L-N-G-I-I-T-Q-F-E-S-L-K-L-Y-R-D-S-L-G-E-A-V-M-R-M-G-D-L-H-S-L-Q-N-R-N-G-K-W-R-E-Q-L-G-Q-K-F-E-E-I-R-W-L-I-E-E-V-R-H-R-L-K-I-T-E-N-S-F-E-Q-I-T-F-M-Q-A-L-Q-L-L-L-E-V-E-Q-E-I-R-T-F-S-F-Q-L-I"} +{"text": "### FUNCTION Involved in host translation shutoff without degradating host RNA By suppressing host gene expression, facilitates the evasion from host type I interferon immune response ### SEQUENCE -M-N-N-S-K-D-N-P-F-R-G-A-I-A-R-K-A-R-I-Y-L-R-E-G-L-D-C-V-Y-F-L-N-K-A-G-Q-A-E-P-C-P-A-C-T-S-L-V-F-Q-G-K-T-C-E-E-H-I-H-N-N-N-L-L-S-W-Q-A-V-K-Q-L-E-K-Q-T-P-Q-R-Q-S-L-N"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-N-I-I-E-G-K-L-I-G-Q-S-L-K-F-G-I-T-I-G-R-F-N-E-F-I-G-G-K-L-L-D-G-A-V-D-A-L-I-R-H-G-V-D-E-K-D-I-E-I-A-W-V-P-G-A-F-E-I-P-L-I-A-K-K-M-A-K-S-K-K-Y-D-G-I-I-C-L-G-A-V-I-R-G-A-T-T-H-Y-D-Y-V-A-S-E-V-S-K-G-I-A-K-I-T-L-D-E-E-V-P-V-I-F-G-V-L-T-T-E-N-I-E-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-Y-E-A-A-C-T-A-I-E-M-A-N-I-I-N-I-I"} +{"text": "### FUNCTION Cell-to-cell movement function ### SEQUENCE -M-A-C-C-R-C-D-S-S-P-G-D-Y-S-G-A-L-L-I-L-F-I-S-F-V-F-F-Y-I-T-S-L-S-P-Q-G-N-T-Y-V-H-H-F-D-S-S-S-V-K-T-Q-Y-V-G-I-S-T-N-G-D-G"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-D-F-Y-S-L-F-L-I-A-I-A-L-S-L-D-A-F-G-V-A-L-C-I-G-L-N-N-N-V-D-L-K-Y-K-S-S-C-A-I-Y-F-G-F-F-Q-F-L-F-A-I-I-G-G-Y-A-G-F-L-F-N-K-Y-I-A-T-M-P-Q-I-V-G-G-V-V-I-C-I-V-G-I-I-M-I-K-E-G-I-E-N-E-D-S-C-K-I-L-K-P-G-M-N-I-I-L-G-I-S-V-S-I-D-A-M-V-V-G-F-T-A-L-N-K-I-Q-S-G-L-L-I-L-R-D-T-L-F-I-G-I-V-T-L-F-V-S-I-L-A-F-I-T-S-K-Y-L-K-K-I-D-V-I-G-K-Y-A-D-Y-I-G-G-I-I-L-I-F-F-G-L-K-M-I-F-F"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-F-K-D-V-V-E-E-F-K-K-F-A-I-K-G-N-A-I-D-L-A-V-G-V-V-I-G-G-A-F-G-K-I-V-T-S-L-V-Q-D-I-I-M-P-A-V-G-L-L-L-G-K-V-N-F-K-T-L-S-L-T-V-T-S-I-D-G-S-E-I-V-L-K-Y-G-Q-F-I-Q-S-V-V-D-F-I-I-I-S-F-S-I-F-L-F-V-K-L-I-N-S-F-K-K-K-E-E-E-K-P-K-V-E-E-P-S-K-E-E-K-L-L-A-E-I-R-D-I-L-K-E-S-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-V-K-G-R-S-N-K-T-L-A-E-N-R-K-A-R-H-D-Y-F-V-E-E-A-Y-E-A-G-I-E-L-V-G-T-E-V-K-S-I-R-E-G-K-A-N-L-K-D-S-Y-A-E-I-R-N-G-E-V-F-L-R-N-M-H-V-S-P-Y-E-Q-G-N-I-F-N-K-D-P-L-R-D-R-K-L-L-L-H-K-M-Q-I-L-K-L-T-A-Y-T-T-Q-Q-G-Y-T-L-I-P-L-S-L-Y-L-K-N-G-R-V-K-V-N-L-A-V-A-K-G-K-K-N-Y-D-K-R-Q-D-L-I-E-K-A-A-K-R-D-I-E-R-E-L-K-D-R-S-R-Y"} +{"text": "### FUNCTION Minor structural protein present in one or two copies per virion Does not seem to play a role in capsid assembly, but is essential for production of infectious virus ### SEQUENCE -M-A-F-L-M-S-E-F-I-G-L-G-L-A-G-A-S-V-L-S-N-A-L-L-R-R-Q-E-L-Q-L-Q-R-Q-A-L-E-N-G-L-V-L-K-A-D-Q-L-G-R-L-G-F-N-P-N-E-V-K-N-V-I-V-G-N-S-F-S-S-N-V-R-L-S-N-M-H-N-D-A-S-V-V-N-A-Y-N-V-Y-N-P-A-S-N-G-I-R-K-K-I-K-S-L-N-N-S-V-K-I-Y-N-T-T-G-E-S-S-V"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-F-L-L-V-G-L-G-N-P-G-K-E-Y-E-K-T-R-H-N-I-G-F-E-A-V-D-K-I-S-Y-E-Y-N-I-P-I-K-R-E-R-F-K-G-V-F-G-D-G-R-I-S-N-E-K-V-I-L-L-K-P-T-T-Y-M-N-L-S-G-E-S-L-R-E-I-I-E-Y-Y-N-I-P-I-T-N-V-I-V-I-Y-D-D-V-D-L-E-V-G-R-L-R-I-R-T-K-G-S-A-G-G-H-N-G-I-K-S-I-I-Y-N-L-N-S-E-D-F-I-R-L-R-I-G-V-G-K-P-Q-R-D-M-V-S-H-V-L-G-K-F-A-K-E-D-E-K-N-I-E-E-V-L-K-I-I-P-E-L-A-Y-T-I-I-N-Q-G-P-Q-E-A-M-N-K-Y-N-N-F-R-A-E"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-K-G-V-K-F-M-K-E-I-I-L-A-G-G-C-F-W-G-V-E-E-Y-F-S-R-I-Y-G-V-V-D-T-K-V-G-Y-V-N-G-V-T-K-N-P-S-Y-E-E-V-C-N-G-N-T-G-Y-A-E-G-C-Y-I-K-F-D-E-S-I-I-G-L-K-R-I-L-D-K-F-W-D-I-I-D-P-T-I-L-N-R-Q-G-P-D-V-G-H-Q-Y-R-T-G-I-Y-Y-Y-D-K-E-D-L-D-D-I-L-K-S-K-D-E-I-S-K-K-Y-D-K-P-I-V-T-E-V-E-K-V-T-Y-F-Y-L-A-E-E-Y-H-Q-K-Y-L-K-K-N-P-N-G-Y-C-H-I-N-L-D-N"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-L-K-D-V-K-K-L-G-K-K-D-D-V-V-N-V-S-D-G-Y-A-R-N-F-L-F-P-R-K-L-A-L-E-A-K-E-S-N-L-N-L-L-N-N-K-K-E-A-E-R-K-Q-K-L-A-E-L-E-E-A-Q-K-L-A-E-E-L-K-N-Q-E-L-I-L-K-V-K-S-G-D-N-G-K-L-F-G-S-I-T-G-K-D-I-S-D-E-L-K-K-K-F-K-L-D-I-D-R-R-K-I-N-V-E-N-I-R-Q-L-G-V-Y-D-V-E-I-K-L-Y-P-E-V-S-T-K-I-K-V-K-I-E-D-I"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-R-G-G-V-P-N-F-G-G-G-N-I-N-N-L-M-K-Q-A-Q-K-F-Q-Q-Q-M-E-E-M-Q-G-Q-L-E-N-K-K-F-Q-A-S-V-G-G-G-A-V-T-A-I-A-N-G-K-K-E-I-V-D-I-R-I-K-P-E-V-V-D-P-D-D-V-E-M-L-E-D-L-I-L-S-A-C-N-E-A-L-K-K-A-E-H-E-T-A-N-E-M-K-K-L-T-G-G-M-N-L-P-G-M-F"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-E-F-Y-P-I-A-I-E-K-L-I-E-E-F-A-K-L-P-G-I-G-K-K-T-A-Q-R-L-T-L-Y-V-L-N-L-P-R-E-E-V-E-E-F-A-N-A-L-I-K-A-R-G-T-I-K-Y-C-S-V-C-G-N-F-T-D-K-D-P-C-A-I-C-S-N-P-N-R-D-K-N-T-I-C-V-V-E-H-P-K-D-I-M-T-M-E-K-V-R-E-Y-N-G-M-Y-H-V-L-H-G-T-I-S-P-M-A-G-R-G-P-N-D-I-K-L-K-E-L-I-S-R-I-N-G-E-I-K-E-V-I-V-A-T-N-P-N-V-E-G-E-A-T-A-M-Y-I-S-K-I-L-K-P-L-G-A-K-V-T-R-I-A-H-G-I-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-A-K-A-L-E-G-R-K-E-I"} +{"text": "### FUNCTION May mediate protein transfer from the Sec translocon to the chaperone network via its extracellular C-terminal region ### SEQUENCE -M-I-K-N-S-Y-I-N-E-K-L-N-F-Y-Q-K-S-F-L-T-C-M-L-L-I-V-I-V-I-V-Y-F-F-S-K-N-Y-L-D-K-P-K-N-S-Y-V-H-T-K-M-M-T-F-L-T-N-S-N-E-L-N-I-S-K-N-L-I-W-T-K-K-T-I-S-G-N-L-M-S-L-K-L-A-K-V-Y-V-I-N-N-Q-L-E-K-A-L-K-I-L-E-K-S-K-N-N-S-V-D-L-N-F-F-N-L-I-S-F-K-I-A-Q-I-Y-F-Q-K-N-N-I-K-K-A-I-T-T-I-K-D-I-L-G-D-S-W-D-S-I-R-N-N-F-I-G-D-V-Y-F-K-L-D-N-Q-K-R-A-V-T-L-W-K-R-S-I-I-Q-N-K-K-I-E-F-E-K-I-I-Q-M-K-I-N-N-Y-N"} +{"text": "### FUNCTION Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-P-K-L-I-I-L-P-H-K-I-L-L-P-K-G-G-V-F-N-A-M-K-G-E-S-I-L-N-V-A-L-R-N-N-V-E-I-E-H-A-C-E-K-S-C-V-C-T-T-C-H-C-Y-I-W-K-G-A-S-S-L-S-I-C-E-E-K-E-E-D-V-L-D-K-A-W-N-L-Q-F-N-S-R-L-S-C-Q-A-K-I-N-N-K-D-I-E-I-E-I-P-K-Y-T-I-N-Q"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-Y-F-K-L-F-N-L-P-Q-K-F-E-L-D-V-N-N-L-T-S-Q-Y-Y-N-L-Q-K-K-F-H-P-D-S-Y-Q-D-K-N-I-Y-T-K-K-Y-L-E-K-S-M-L-L-N-Q-G-Y-Q-T-L-K-N-M-L-T-R-A-E-H-L-L-F-L-N-N-Y-K-V-D-K-K-K-K-I-V-F-N-A-K-F-L-E-M-Q-I-E-L-F-E-R-L-E-I-H-K-N-K-N-N-K-H-E-I-N-K-I-L-L-E-V-S-Q-I-E-K-N-Y-I-K-K-L-K-N-F-C-N-L-E-K-W-K-I-A-H-S-I-L-Y-K-L-L-F-L-T-K-F-I-K-K-T-K-K-I-Q-H-E-I-I-N"} +{"text": "### FUNCTION A scaffold on which IscS assembles Fe-S clusters Subsequently gives the nascent cluster to other proteins It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters ### SEQUENCE -M-A-Y-S-K-K-V-I-D-H-Y-E-N-P-R-N-V-G-S-F-K-T-I-D-A-N-V-G-S-G-L-V-G-A-P-A-C-G-D-V-M-K-L-Q-I-K-V-N-K-N-G-I-I-Q-D-A-C-F-K-T-Y-G-C-G-S-A-I-A-S-S-S-L-V-T-E-W-I-K-G-K-S-L-I-E-A-E-N-I-K-N-T-N-I-A-E-E-L-D-L-P-P-V-K-I-H-C-S-I-L-A-E-D-A-I-K-A-A-I-T-D-Y-K-N-K-N-K"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-M-N-Y-R-H-I-L-V-M-I-D-L-S-P-D-S-Y-S-L-I-H-K-A-S-F-I-S-N-L-H-N-D-A-K-I-S-L-I-Y-V-N-T-D-Y-S-D-A-Y-T-G-L-I-D-V-D-I-R-N-I-Q-S-Y-R-L-Q-D-I-N-N-M-L-K-N-L-K-N-Y-I-Y-F-P-V-H-K-V-F-I-G-N-G-D-M-T-S-C-L-L-D-V-T-Q-K-Y-N-I-D-L-I-I-F-G-H-Y-Q-D-F-W-S-K-I-V-F-S-L-R-Q-I-I-N-S-L-H-I-D-M-L-I-V-P-F-Y"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-K-I-H-P-D-Y-F-K-I-N-V-T-C-S-C-G-N-N-I-N-I-F-S-T-L-S-K-N-I-N-V-D-V-C-S-K-C-H-P-F-Y-T-G-Q-Q-R-T-S-D-T-G-G-R-I-E-K-F-H-K-R-F-N-I-S-S-H"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-N-T-D-I-K-N-L-I-W-I-D-L-E-M-T-G-L-N-P-N-I-H-K-I-I-E-I-A-T-L-I-T-D-K-N-L-K-I-L-S-Y-G-P-V-I-A-I-Y-Q-N-N-H-Q-L-S-F-M-D-P-W-N-N-K-M-H-T-K-N-G-L-I-T-R-I-K-N-S-L-Y-T-E-H-L-A-E-I-K-T-I-T-F-L-K-K-W-V-P-K-N-T-S-P-M-C-G-N-S-I-S-T-D-R-Q-F-L-F-K-Y-M-P-T-L-E-K-Y-F-H-Y-R-Q-I-D-V-S-T-I-K-E-L-A-L-R-W-K-P-K-I-Y-N-K-L-K-K-K-T-L-I-K-H"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-I-L-L-I-H-P-D-C-S-E-K-L-P-I-M-I-E-K-F-K-K-L-V-I-G-Y-K-G-R-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-S-I-N-K-L-H-K-A-H-Y-F-L-M-N-I-E-V-P-S-N-C-I-Q-D-L-S-N-T-F-R-Y-D-D-L-V-I-R-N-I-I-M-H-V-K-K-S-V-T-E-I-S-P-M-L-K-S-K-E-D-K-L-D-K-K-D-R-V-V-V-S"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-E-K-L-D-N-L-G-N-K-G-D-I-L-F-V-K-S-G-Y-A-R-N-F-L-I-P-Y-G-K-A-I-F-A-T-K-D-N-I-K-F-E-I-N-K-K-E-E-L-E-R-E-L-I-K-K-I-S-I-A-K-T-K-C-E-K-I-K-N-I-K-S-I-V-I-P-A-Q-V-G-I-E-G-K-L-F-G-S-V-G-S-R-D-I-A-K-K-L-S-E-L-S-N-I-K-I-K-K-H-E-I-Y-F-L-N-G-A-L-K-H-V-G-Q-H-K-V-I-F-K-P-H-H-S-V-S-I-T-V-E-I-N-I-V-S-Q-D-K-D-K"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-I-I-I-A-L-D-F-G-T-K-N-I-G-V-A-V-G-Q-N-Y-T-N-T-A-R-S-L-P-S-I-K-V-K-N-K-K-L-N-I-E-K-L-N-K-L-I-D-E-W-K-P-N-A-I-V-V-G-H-P-L-N-I-D-G-T-K-Q-K-I-T-Q-C-S-E-N-F-S-K-K-L-K-N-I-F-K-I-P-I-L-L-H-D-E-R-L-S-T-V-E-A-K-A-I-L-F-E-K-Y-G-Y-K-S-L-K-K-E-R-I-D-S-M-S-A-V-I-I-L-E-S-W-F-L-Y-S-K-N"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-S-R-G-I-N-K-V-I-L-I-G-Y-L-G-Q-D-P-D-V-R-Y-M-Q-N-G-S-A-V-T-N-I-T-L-A-T-S-E-T-W-K-D-K-N-N-G-E-I-K-E-K-T-E-W-H-R-I-V-F-F-N-K-L-A-E-I-A-G-E-Y-L-K-K-G-S-Q-V-Y-I-E-G-S-L-Q-T-R-K-W-K-D-Q-N-G-I-E-R-Y-I-T-E-I-I-V-S-V-G-G-T-M-Q-M-L-G-S-R-N-S-S-S-L-T-A-S-S-G-L-S-K-N-N-D-N-L-S-K-Q-L-L-S-E-K-K-Q-E-S-F-N-D-S-K-L-Q-N-N-N-L-D-F-D-D-E-D-I-P-F"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-V-S-V-S-Q-S-A-Q-N-Y-F-L-N-L-L-K-K-Q-K-Y-G-T-N-I-R-V-Y-V-K-Y-P-G-T-P-V-A-K-C-G-V-S-Y-C-Y-K-D-D-V-T-R-L-D-V-A-F-T-M-N-K-F-I-V-Y-V-Y-K-P-H-I-P-Y-L-R-E-S-K-I-D-I-N-V-E-E-C-N-S-Q-L-T-L-I-A-P-Y-A-N-K-C-Y-F-I-K-N-N-D-L-K-R-R-V-E-N-F-L-N-L-N-I-N-P-Q-L-S-A-H-G-G-K-V-D-L-M-N-I-T-E-S-G-Y-L-S-L-K-F-S-G-G-C-N-G-C-S-M-V-Q-K-T-L-K-E-G-I-E-K-Q-I-L-A-K-F-S-E-F-K-G-V-Y-D-I-T-Q-H-N-R-G-N-H-S-Y-Y"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-N-Y-T-V-L-V-I-G-P-P-Y-S-T-Q-N-S-T-S-A-F-L-F-S-R-A-V-I-L-N-H-H-K-L-L-S-I-F-F-Y-C-D-G-A-L-N-A-N-K-F-I-S-P-N-F-N-E-C-N-L-V-E-E-W-T-W-L-H-N-K-Y-L-V-K-L-C-V-C-V-S-A-A-L-R-R-G-V-I-D-V-V-S-N-T-K-Q-N-K-N-I-K-V-G-N-L-K-S-S-F-F-L-T-G-L-G-E-F-S-N-Y-L-K-I-S-D-R-V-I-Q-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-K-K-I-A-F-V-F-S-Y-V-P-H-G-V-S-L-G-R-E-G-L-D-L-L-L-S-V-S-I-M-N-S-K-I-S-V-F-F-I-G-D-G-I-F-Q-L-L-K-N-Q-K-P-D-E-I-L-S-K-N-Y-V-L-S-F-K-I-L-P-F-F-G-I-Y-D-F-F-L-C-N-E-S-L-K-E-R-G-L-F-K-K-T-D-F-L-L-D-V-S-I-L-S-A-I-E-I-R-N-K-L-K-N-S-D-L-I-I-N-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-L-H-I-L-M-R-S-P-F-E-T-N-M-V-L-L-M-N-M-L-E-S-V-D-D-I-L-M-L-Q-N-S-V-V-L-A-L-K-N-N-V-F-L-N-K-I-L-S-Y-S-V-S-M-Y-A-L-K-Q-D-L-C-A-R-G-I-L-D-N-I-S-P-N-V-N-V-I-G-Y-N-R-F-V-D-L-T-V-K-H-K-Q-Q-M-S-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-V-N-Q-L-V-R-K-S-R-S-R-K-L-I-K-N-N-V-P-A-L-N-K-C-P-Q-K-R-G-V-C-I-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-Y-E-V-T-A-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-I-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-V-I-R-G-A-L-D-C-S-G-V-K-S-R-S-Q-G-R-S-K-Y-G-V-K-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-G-I-G-H-R-K-I-L-S-D-P-K-F-S-S-E-M-V-A-K-L-I-N-I-I-M-V-D-G-K-K-S-I-A-E-E-I-V-Y-Q-A-L-T-M-L-A-K-K-I-G-K-P-E-L-E-V-L-E-L-A-L-E-N-V-R-P-T-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-I-E-V-R-P-V-R-R-H-A-L-A-M-R-W-I-V-H-S-A-R-K-R-I-D-K-S-M-I-I-R-L-S-N-E-L-S-D-A-I-E-N-K-G-S-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-Q-N-Q-R-I-R-I-R-L-K-A-F-D-H-R-L-I-D-Q-S-T-S-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-H-K-E-K-F-T-V-L-I-S-P-H-V-N-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-L-I-D-I-V-E-P-T-E-K-T-V-D-A-L-M-R-L-D-L-A-A-G-V-D-V-Q-I-S-L-G"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-Y-E-K-I-L-L-K-V-L-L-G-P-H-I-S-E-K-S-S-T-L-S-G-N-F-S-T-V-I-I-K-V-S-I-C-A-T-K-L-E-I-K-R-A-V-Q-N-M-F-N-V-A-V-K-N-V-N-T-L-V-V-Q-G-K-C-K-R-K-K-S-R-I-T-C-S-S-N-W-K-K-A-Y-V-T-L-K-R-G-Q-N-I-N-F-I-G-S-S-E"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-I-A-L-L-R-K-V-E-Q-A-V-E-I-R-D-K-K-P-I-R-T-W-S-R-R-S-T-I-F-P-K-M-V-G-L-T-M-L-I-H-N-G-R-Q-H-I-P-V-F-I-T-E-D-M-V-G-H-K-L-G-E-F-V-L-T-R-T-Y-R-G-H-T-A-D-K-K-V-K-K-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-N-T-K-F-R-K-M-H-K-G-K-N-R-G-L-A-I-G-T-N-V-H-F-G-L-Y-G-L-K-A-I-T-R-G-R-L-K-S-S-Q-I-E-S-A-R-R-A-I-T-R-A-I-K-R-Q-G-K-I-W-I-R-I-F-P-D-K-P-I-T-K-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-V-Q-P-G-K-I-L-Y-E-I-S-G-V-S-E-E-L-S-R-I-A-F-K-L-A-A-A-K-L-P-V-K-T-M-F-V-T-K-L-V-M"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-I-D-K-F-R-T-L-S-G-Q-V-I-S-N-K-M-Q-K-S-A-I-V-S-I-K-R-L-I-K-H-P-L-Y-K-K-F-V-K-K-T-T-K-L-C-I-H-D-E-N-N-Q-C-S-F-G-D-I-V-E-I-R-E-C-R-P-I-S-K-T-K-S-W-M-L-V-R-I-S-K-K-S-L-R-S"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-E-Q-S-I-L-N-V-A-D-N-S-G-A-R-L-A-M-C-I-K-V-L-G-G-S-R-R-R-Y-A-G-I-G-D-I-I-K-I-S-I-K-E-A-I-P-R-G-K-V-K-K-G-E-V-F-K-A-V-I-I-R-T-K-K-G-V-K-R-S-D-G-S-I-I-R-F-D-T-N-A-C-V-V-L-N-N-N-D-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-N-D-K-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-K-K-N-D-Q-V-I-V-L-I-G-K-D-K-G-K-I-G-I-V-R-K-V-I-A-K-S-K-V-I-V-E-G-V-N-I-V-K-K-H-T-K-P-S-P-S-Q-N-K-K-G-G-I-V-E-Q-E-S-S-I-N-I-S-N-I-A-I-L-N-P-T-T-K-K-S-D-R-I-G-F-R-V-K-N-G-K-K-V-R-F-F-K-S-N-N-T-I-C-N"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-V-A-L-Y-D-Y-Y-K-N-S-I-S-K-K-L-M-L-N-F-N-Y-S-S-V-M-Q-V-P-K-I-D-K-I-T-L-N-I-G-V-G-I-A-T-I-D-K-K-N-L-D-F-A-I-S-D-L-T-K-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-I-A-S-F-K-I-R-K-G-Y-P-I-G-C-K-V-T-L-R-G-N-R-K-W-D-F-F-E-R-L-I-F-I-V-I-P-R-I-R-D-F-R-G-F-S-N-K-S-F-D-G-K-G-N-Y-S-I-G-I-K-E-Q-I-I-F-P-E-I-D-F-D-K-I-D-R-I-R-G-I-N-I-T-I-T-T-T-A-L-S-D-R-E-G-Y-A-L-L-S-A-F-N-F-P-F-R-T"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-E-V-K-R-I-K-L-A-K-K-F-Y-S-R-R-E-H-L-K-S-I-I-S-D-L-S-V-L-E-Q-D-R-W-K-A-V-L-K-L-Q-T-F-P-R-D-S-S-P-I-R-Q-R-N-R-C-S-Q-T-G-R-P-H-A-F-L-R-K-F-G-L-S-R-I-K-V-R-E-A-A-M-R-G-E-I-P-G-L-K-K-S-S-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-A-K-Q-P-I-V-I-P-S-D-V-S-I-T-L-I-G-Q-M-V-I-V-K-G-S-K-G-E-L-K-R-L-I-H-D-S-V-L-V-K-S-V-K-S-C-L-V-F-S-S-R-I-N-S-S-V-K-G-W-A-Q-A-G-T-A-R-S-L-V-N-S-M-I-H-G-V-T-V-G-F-F-K-K-L-K-L-F-G-V-G-Y-R-I-S-I-N-S-S-K-N-L-N-M-S-L-G-Y-S-H-I-I-E-Y-V-L-P-F-G-I-F-V-E-S-I-S-Q-A-E-I-I-V-K-G-I-N-K-Q-L-V-G-Q-V-A-A-N-L-R-A-Y-R-K-S-E-P-Y-K-G-K-G-I-R-Y-S-N-E-I-V-R-V-K-E-A-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-I-S-I-N-K-K-K-A-R-L-R-R-A-A-R-T-R-F-Q-I-K-K-L-H-L-I-R-L-V-V-H-R-T-S-K-H-I-Y-A-Q-I-I-D-S-K-N-A-L-V-L-T-S-A-S-T-V-E-K-E-I-L-N-L-V-K-Y-T-G-N-I-H-A-S-I-C-I-G-K-K-I-A-E-R-A-L-M-K-G-I-I-N-V-S-F-D-R-S-G-F-Q-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-S-G-L-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-N-I-G-R-N-V-S-G-D-L-K-E-K-L-I-S-V-N-R-V-S-K-T-V-K-G-G-R-I-F-S-F-S-A-L-T-V-V-G-D-G-H-G-K-V-G-F-G-Y-G-K-A-R-E-V-P-S-A-I-Q-K-A-M-E-K-A-R-R-N-M-I-Q-V-P-L-N-N-G-T-L-Q-Y-S-V-T-G-S-Y-T-G-S-Y-I-F-M-K-P-A-S-N-G-T-G-I-I-A-G-G-A-M-R-S-V-L-E-V-A-G-V-H-N-V-L-A-K-T-Y-G-S-T-N-P-I-N-V-V-R-A-T-M-L-V-L-E-S-M-K-S-P-E-M-I-A-L-K-R-N-K-L-V-K-E-I-L-E-N-S-Y-L"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Y-L-N-T-L-S-P-N-S-K-S-H-K-K-S-K-R-V-G-R-G-I-G-S-G-F-G-K-T-S-G-R-G-H-K-G-Q-K-S-R-S-G-C-K-I-R-R-G-F-E-G-G-Q-M-P-L-Y-R-R-I-P-K-F-G-F-V-S-L-K-K-E-K-V-A-E-V-R-L-E-D-L-K-N-F-S-N-C-I-I-N-L-Q-F-L-K-K-T-G-L-I-K-K-N-I-K-Y-V-K-I-I-S-S-G-S-I-I-T-N-I-L-I-I-R-N-L-F-V-S-K-S-V-R-N-I-I-E-S-S-G-G-K-I-E-E-N-N"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-A-N-H-K-H-V-V-V-A-L-M-D-V-Y-G-I-G-K-T-R-S-K-L-I-C-L-R-T-N-I-S-E-S-I-K-I-L-D-L-T-K-D-Q-L-E-L-L-R-C-E-V-L-K-F-V-V-E-G-D-L-R-R-E-V-T-L-S-I-K-R-L-Q-D-L-N-C-Y-R-G-S-R-H-R-K-K-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-L-M-K-K"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-S-K-D-G-L-N-N-L-M-Q-H-A-Q-K-I-Q-E-Q-M-K-K-I-Q-Q-E-V-S-E-I-E-V-T-G-E-S-G-A-G-A-V-K-V-T-L-I-G-S-H-Y-C-K-K-I-E-L-D-K-N-T-I-L-E-H-D-K-E-I-L-E-D-L-I-T-A-A-F-N-D-A-V-R-K-I-S-D-L-Q-K-Q-K-M-S-S-I-S-S-E-M-K-F-S-N-N-L-N-L-P-F"} +{"text": "### FUNCTION Cytochrome bo ### SEQUENCE -M-L-K-N-R-Y-L-K-Y-L-F-I-L-I-L-L-S-I-L-S-I-M-P-I-F-A-I-I-Y-R-I-F-S-R-N-Y-L-Y-A-F-I-I-V-C-L-F-F-Q-I-L-A-H-I-K-F-F-L-N-L-D-F-S-L-E-Q-R-W-K-L-I-S-V-I-F-S-L-V-V-G-L-I-I-L-L-G-S-I-W-V-I-K-N-L-N-N-N-L-C-I-M"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine ### SEQUENCE -M-N-Y-I-P-D-W-N-E-E-L-A-K-K-I-A-K-S-E-F-I-N-M-T-P-D-H-W-E-I-I-Y-I-I-R-N-F-Y-L-N-F-N-L-A-P-S-I-R-I-L-I-K-T-L-E-K-M-K-Y-N-K-K-K-C-S-S-R-Y-L-L-K-L-F-P-K-N-P-I-K-Q-A-S-K-I-A-G-V-P-K-T-N-D-C-I"} +{"text": "### FUNCTION Sulfur carrier protein involved in sulfur trafficking in the cell Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine in tRNA Interacts with IscS and stimulates its cysteine desulfurase activity Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin ### SEQUENCE -M-T-V-D-N-N-V-L-D-L-R-K-L-R-C-P-E-P-I-M-L-L-R-K-K-I-R-E-I-K-N-G-T-T-L-L-I-L-S-D-D-P-S-T-I-R-E-I-P-Q-Y-C-K-F-M-H-H-K-L-L-K-I-N-T-K-D-T-I-Y-K-F-W-I-Q-K-T-H-K-M"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-Y-I-Q-K-Y-E-K-K-Q-I-K-K-T-I-P-I-F-K-S-G-D-T-I-I-I-K-V-W-I-V-E-G-T-K-K-R-I-Q-L-F-E-G-I-V-I-A-I-R-N-R-G-F-N-S-S-F-C-V-R-K-V-S-N-G-E-G-I-E-R-V-F-P-K-Y-S-P-I-I-E-E-I-I-V-K-R-H-G-D-V-K-K-S-K-L-Y-Y-L-R-N-R-I-G-K-S-A-K-I-R-E-L-I-S-K-K-T-S"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-Y-I-K-S-F-S-A-K-S-N-D-F-K-K-M-W-Y-C-I-D-A-T-G-K-I-L-G-R-L-A-T-N-I-A-S-R-L-R-G-K-H-K-V-E-Y-T-P-H-V-D-I-G-D-Y-L-I-V-I-N-A-K-N-I-K-V-T-G-K-K-C-T-D-K-F-Y-Y-H-H-T-G-Y-V-G-G-L-K-K-I-A-F-K-D-M-L-H-R-Y-P-E-R-I-I-E-I-A-V-R-G-M-L-P-K-G-P-L-G-R-S-M-F-K-K-L-K-V-Y-A-N-D-N-H-N-H-S-A-Q-N-P-K-I-L-N-I"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-F-K-S-G-G-K-Q-H-K-V-I-K-G-Q-T-I-R-L-E-K-I-N-Q-S-I-G-T-Q-I-K-F-K-K-I-L-M-C-C-N-G-T-H-I-T-I-G-K-P-H-I-H-N-N-F-I-L-A-N-I-I-N-H-G-R-H-K-K-I-K-I-I-K-F-N-R-R-K-H-Y-K-K-Q-Q-G-H-R-Q-N-F-T-D-V-L-I-T-N-I-H-N-N-Y-R-E-Q-N-N-G-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-E-N-M-N-I-K-S-K-I-I-T-Q-F-G-V-N-S-K-D-S-G-K-S-E-V-Q-I-A-L-L-T-N-R-I-N-Y-L-Q-N-H-F-S-L-H-K-K-D-H-C-S-R-R-G-L-L-N-M-V-S-K-R-R-K-L-L-N-Y-L-K-D-E-N-I-S-R-Y-I-N-I-I-N-Q-L-K-L-R-R"} +{"text": "### FUNCTION Structural component of flagellum, the bacterial motility apparatus Part of the rod structure of flagellar basal body ### SEQUENCE -M-L-D-K-I-N-N-D-F-N-I-N-K-I-L-L-N-L-H-A-Y-R-Q-E-I-L-A-S-N-I-A-N-A-N-T-P-G-H-K-S-S-D-I-N-F-S-K-T-F-G-K-L-F-S-N-A-L-Q-G-K-K-N-N-L-T-T-T-S-N-K-H-I-S-N-N-D-N-V-E-L-S-N-Y-D-E-Q-T-V-K-N-N-S-Y-V-S-K-N-N-A-I-N-I-D-V-D-R-I-N-F-V-H-N-G-L-K-Y-N-A-D-V-V-F-I-N-N-K-F-K-N-I-M-N-V-L-K-G"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-A-L-L-D-F-F-L-S-R-K-K-N-T-A-N-I-A-K-E-R-L-Q-I-I-V-A-E-R-R-R-M-D-T-E-P-Q-Y-L-P-K-L-K-K-E-I-F-Q-V-I-C-K-Y-I-K-I-N-P-E-K-I-K-I-Q-L-D-Q-T-N-K-N-I-S-I-L-E-L-N-V-T-L-S-E"} +{"text": "### FUNCTION Low-potential electron donor to a number of redox enzymes ### SEQUENCE -M-E-S-I-G-I-F-F-G-S-D-T-G-N-T-E-N-V-A-K-L-I-H-K-Y-I-G-T-N-I-S-S-I-H-D-I-A-N-T-N-K-K-D-I-E-L-F-N-I-L-I-F-G-V-S-T-W-Y-Y-G-E-L-Q-C-D-W-D-D-F-L-P-T-L-K-K-I-N-F-N-N-K-I-I-A-L-F-G-C-G-D-Q-E-D-Y-S-E-Y-F-C-D-G-I-G-I-L-Y-N-V-I-R-L-S-K-N-V-R-F-I-G-S-W-T-S-K-G-Y-S-F-E-C-S-K-A-L-D-K-N-K-N-F-L-G-L-V-I-D-E-D-R-Q-P-E-Q-S-N-Q-R-I-I-Q-W-T-K-K-I-K-T-E-L-N-S-L-L-N"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-F-L-L-N-S-I-P-T-I-S-F-F-I-F-Y-K-F-Y-D-I-F-I-A-S-F-S-L-M-I-A-S-L-F-T-F-I-I-T-S-I-L-F-N-S-I-N-K-H-D-L-I-N-L-I-F-V-I-V-F-G-F-L-T-L-F-Y-H-N-S-S-Y-I-K-W-K-V-T-I-I-Y-F-L-I-S-I-V-F-L-I-N-Y-L-F-I-K-N-N-L-L-N-I-I-F-K-N-T-I-Q-L-S-K-N-V-W-R-K-L-S-L-F-W-S-I-F-F-L-I-C-A-V-S-N-T-Y-I-I-L-Y-F-S-E-Q-T-W-V-T-F-K-I-F-G-L-T-I-L-T-L-I-A-V-I-I-N-G-F-Y-I-Y-F-L-K-S-K-I-I-Q"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-R-N-S-N-R-K-P-N-E-I-C-I-N-R-K-A-K-Y-S-F-S-I-K-E-T-F-E-A-G-I-V-L-L-G-W-E-V-K-S-V-R-C-G-K-I-N-I-S-N-S-Y-I-S-L-K-N-G-E-M-Y-L-V-N-S-Q-F-D-P-I-S-K-S-N-L-Y-I-T-Y-E-C-N-R-I-K-K-I-L-L-R-K-R-E-I-T-Y-L-Y-S-K-L-Y-K-S-H-L-T-I-I-V-L-S-I-F-F-K-K-Q-W-C-K-V-K-I-G-I-A-K-G-K-T-I-K-D-K-R-E-H-K-K-L-S-E-W-K-K-T-Q-N-R-F-V-K-R-I-R-H"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-I-D-N-D-L-L-S-K-N-K-E-A-K-V-V-S-E-N-S-T-V-E-I-N-D-V-T-N-S-D-S-K-N-T-D-N-D-F-Q-T-E-E-L-N-N-F-E-K-I-F-L-N-L-N-S-D-L-L-N-Q-Q-L-L-V-K-N-N-L-K-L-Y-K-I-R-A-E-K-E-I-N-R-A-Y-K-F-S-L-K-S-F-I-S-S-L-F-P-V-I-D-S-M-E-Y-A-L-N-L-F-K-K-D-D-K-I-L-C-L-I-F-N-E-L-D-N-V-S-Q-S-L-M-N-L-L-V-K-F-G-V-T-S-I-K-D-I-N-I-A-F-N-P-D-I-H-Q-A-I-T-T-Q-V-S-K-D-I-K-N-N-Y-V-I-S-I-M-Q-K-G-Y-L-L-Y-D-R-L-L-R-P-A-M-V-I-V-S-K-N-D-I"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-Y-N-S-N-I-T-D-I-T-T-L-L-P-H-R-Y-P-F-L-L-I-D-R-I-I-A-Y-Q-K-N-F-N-I-L-T-I-K-N-I-S-Y-S-E-F-C-F-T-G-H-F-Y-K-N-P-V-F-P-G-V-L-I-L-E-A-I-A-Q-S-A-C-L-L-V-Y-K-S-F-G-M-S-Y-K-N-N-L-F-Y-L-T-N-I-I-D-V-K-F-K-K-K-V-I-P-G-D-Q-M-L-I-N-V-F-V-D-K-H-H-H-R-L-I-R-F-V-G-H-V-S-V-S-K-Y-I-V-C-K-A-T-I-S-C-L-L-T-N-D-V-V-S-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-E-R-I-K-N-F-T-S-S-K-M-D-H-C-V-H-M-F-V-N-Q-L-N-T-L-R-S-S-R-A-S-P-S-I-L-D-T-I-L-I-D-Y-L-G-Q-K-I-Q-L-K-K-L-S-N-I-I-V-E-N-V-N-T-L-R-I-T-L-F-D-P-K-I-K-N-N-V-E-K-A-I-I-S-S-K-L-D-L-I-P-I-F-I-N-N-Y-F-Q-I-K-I-P-V-L-T-E-E-R-R-L-Q-L-I-K-L-A-K-K-M-A-E-N-S-R-I-C-I-R-N-I-R-R-L-S-N-E-K-I-K-L-F-L-K-D-K-I-I-S-S-D-K-E-R-R-L-Q-H-E-V-Q-D-I-T-N-S-Y-M-E-K-I-N-V-I-L-S-K-K-E-K-D-L-L-K"} +{"text": "### FUNCTION Essential cell division protein ### SEQUENCE -M-N-K-N-Y-N-L-S-K-I-I-F-N-D-L-I-S-F-Y-K-T-Q-L-I-L-I-F-M-I-F-I-S-A-L-L-I-I-T-I-I-H-K-T-R-L-L-T-S-Q-Q-E-E-L-D-I-I-K-K-K-Q-M-P-L-N-L-E-K-Y-I-S-T-S-R-L-K-F-K-H-E-K-I-D-T"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-K-N-N-I-S-K-F-P-L-S-F-S-K-S-A-I-K-K-I-K-T-I-I-S-E-K-N-I-P-N-L-K-F-R-V-Y-I-A-G-G-G-C-S-G-F-Q-Y-K-F-K-F-D-K-N-K-N-K-N-D-T-I-V-N-I-F-N-N-I-I-I-I-D-P-I-S-L-Q-Y-L-R-G-G-Q-I-D-Y-I-E-N-L-E-G-S-K-F-I-I-L-N-P-K-A-K-H-T-C-G-C-G-S-S-F-S-I"} +{"text": "### FUNCTION Transcription factor that acts by binding directly to the RNA polymerase Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters ### SEQUENCE -M-Q-K-E-K-N-K-K-Q-S-S-L-S-I-L-F-M-A-G-V-Q-P-Y-K-N-K-K-N-E-K-Y-M-N-T-K-Q-I-D-H-F-K-K-I-L-I-A-W-K-N-Q-L-R-N-D-I-S-Q-T-R-L-N-I-Q-D-K-A-T-N-Y-P-D-P-I-D-R-A-V-Q-E-E-E-F-S-F-E-L-R-H-R-D-R-E-R-K-L-I-E-K-I-E-K-T-L-K-K-V-E-N-K-D-F-G-Y-C-E-S-C-G-I-E-I-G-I-K-R-L-E-A-R-P-T-A-N-L-C-I-D-C-K-T-L-S-E-I-R-E-K-Q-I-L-G"} +{"text": "### FUNCTION Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters ### SEQUENCE -M-N-D-I-I-K-K-I-Q-N-Q-I-Q-N-N-P-I-I-I-Y-M-K-G-S-P-D-A-P-S-C-G-F-S-A-Q-A-V-H-A-I-S-S-C-G-K-K-F-A-Y-I-D-V-L-K-N-P-D-I-R-L-E-L-P-K-Y-A-N-W-P-T-F-P-Q-L-W-V-N-G-E-L-I-G-G-C-N-I-I-L-E-L-F-Q-K-G-E-L-K-K-T-I-S-I-C-D-K-L-N-S"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-D-I-D-K-H-K-K-E-T-Q-T-E-S-K-N-D-L-N-N-T-T-I-T-Q-N-N-V-S-D-D-C-Q-N-Q-D-K-I-N-S-L-K-Q-K-I-L-E-I-K-K-H-I-S-E-V-K-L-R-E-Q-A-E-I-E-N-I-N-K-N-T-K-N-K-I-K-I-I-I-D-T-Q-L-E-N-F-F-R-N-L-I-P-I-I-D-S-L-K-N-I-R-K-D-I-N-K-Y-N-N-I-K-D-N-N-M-I-Q-G-I-P-L-I-L-K-S-L-L-T-V-T-E-K-F-G-L-K-I-N-N-K-K-G-K-L-F-D-P-K-L-H-T-T-I-P-N-E-N-C-K-N-I-N-E-Y-Y-V-S-E-I-I-Q-D-G-Y-T-F-H-E-K-I-I-R-K-A-I-V-K-L-S-K-D-K-K-T"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur ### SEQUENCE -M-E-F-F-F-Y-S-S-S-L-A-T-I-V-F-T-V-C-S-I-F-S-R-N-L-M-Y-S-L-L-Y-L-I-L-S-F-V-F-T-S-C-V-F-F-S-L-G-A-T-F-A-A-A-L-E-V-I-I-Y-A-G-A-I-M-V-L-F-V-F-F-I-M-M-F-N-F-K-K-S-T-L-Y-A-E-K-I-F-D-K-N-N-Y-Y-Y-I-N-F-L-F-L-L-C-I-L-I-F-P-F-F-F-I-L-S-Y-L-Y-K-E-K-I-F-Y-M-V-V-S-T-K-L-V-A-I-K-L-F-S-D-Y-I-L-V-I-E-L-S-S-I-V-L-L-S-A-L-I-I-V-S-H-I-G-K-I-R-R"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-S-K-K-D-S-I-K-S-R-K-K-K-K-L-N-A-S-K-K-S-M-I-K-T-L-I-K-K-V-K-I-A-I-L-S-G-D-K-L-K-S-E-L-A-F-S-K-I-Q-P-I-L-D-R-Y-S-A-K-G-L-I-H-K-N-K-A-A-R-H-K-S-N-L-K-C-K-I-N-A-L"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-L-T-I-Y-G-I-S-R-T-K-C-G-K-K-A-S-R-R-L-R-L-Q-N-K-F-P-A-I-I-H-V-S-L-I-S-N-I-S-I-E-L-S-Q-N-D-F-I-N-I-E-M-K-N-S-D-F-Y-K-S-E-V-I-L-I-V-D-K-V-K-Y-I-V-K-I-Q-E-I-Q-R-H-A-F-K-S-K-I-L-H-I-D-F-L-K-V-S-V"} +{"text": "### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-D-N-F-I-S-H-I-Y-A-V-E-N-S-T-T-I-P-S-S-N-S-Y-S-L-I-F-M-L-L-V-F-L-S-I-F-Y-F-M-I-F-R-P-Q-R-K-K-I-Q-E-H-D-R-L-I-K-S-L-S-Y-G-D-E-V-F-T-S-S-G-F-V-G-K-I-V-K-I-T-K-T-G-Y-I-V-L-E-L-N-N-N-V-E-V-F-V-K-S-D-F-I-V-S-I-F-P-K-G-T-L-K-N-M-K-S-M"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-H-V-K-R-G-V-I-A-R-A-R-H-K-K-V-L-K-Q-A-K-G-Y-Y-G-A-R-S-R-T-Y-R-T-A-R-Q-A-I-I-K-A-G-Q-Y-S-Y-R-D-R-R-Q-R-K-R-Y-F-R-K-L-W-I-T-R-I-N-A-A-V-R-E-N-Q-I-S-Y-S-K-F-M-Y-G-L-K-K-A-S-I-A-V-D-R-K-M-L-S-E-L-A-I-F-D-N-V-S-F-C-S-L-I-K-S-S-K-D-A-L-T-S-I-E-L-N-K-N-L"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-V-M-H-F-F-L-L-F-V-S-N-I-L-I-N-N-F-I-L-V-R-F-L-G-L-C-P-F-M-G-I-S-R-T-I-D-S-A-I-G-M-G-L-A-T-T-C-V-I-V-F-V-S-I-I-S-W-L-I-N-F-Y-I-L-I-P-F-H-L-I-H-L-C-T-M-T-Y-M-L-I-I-A-V-S-V-Q-I-F-E-I-I-V-K-K-V-S-S-T-L-Y-R-L-L-G-I-Y-L-P-L-I-T-T-N-C-S-V-L-A-I-P-L-M-N-T-K-L-N-S-N-F-I-E-S-V-L-Y-G-F-S-S-S-L-G-F-F-L-V-L-V-I-F-S-S-I-R-E-R-I-S-E-S-D-V-P-M-Y-F-R-G-Y-P-I-A-L-I-T-A-S-L-L-A-I-A-F-M-G-F-D-G-L-I-K-F"} +{"text": "### FUNCTION Role in flagellar biosynthesis ### SEQUENCE -M-T-I-E-S-V-M-S-L-F-Y-D-A-M-K-V-T-L-M-I-S-L-P-L-L-L-S-A-L-C-C-G-L-I-V-S-I-F-Q-A-A-T-Q-I-N-E-Q-T-L-S-F-I-P-K-I-A-A-V-L-V-S-I-V-I-F-G-P-W-M-L-V-I-L-S-D-Y-T-H-T-L-F-Y-N-L-S-Y-I-T-Y-S"} +{"text": "### FUNCTION FliN is one of three proteins ### SEQUENCE -M-D-N-I-L-V-N-N-K-N-K-N-L-L-D-L-N-K-E-D-I-K-K-S-C-E-I-E-D-K-I-F-H-S-K-T-V-N-D-V-D-L-N-L-N-S-K-N-D-I-S-S-K-M-K-F-I-M-D-V-P-V-H-L-T-I-E-V-G-T-V-K-I-T-I-K-D-L-L-E-L-R-S-K-S-I-L-V-L-D-K-H-A-G-D-P-L-N-I-L-V-N-G-Y-V-I-A-T-G-E-L-V-V-T-E-N-K-Y-G-I-R-I-I-N-I-I-D-N-S-V-F-K-K-L"} +{"text": "### FUNCTION Flagellar protein that affects chemotactic events ### SEQUENCE -M-Y-K-K-K-R-C-F-T-L-L-K-Y-L-D-V-K-S-N-Y-H-I-V-L-N-L-K-K-I-L-S-G-I-I-Q-V-K-A-Q-L-D-I-L-M-S-Y-Q-C-E-Y-L-K-C-L-D-Q-E-L-K-F-Y-I-S-G-T-R-L-A-H-Y-Y-N-F-I-A-F-L-I-D-G-V-N-K-Q-N-D-T-M-C-K-L-Y-K-Q-Y-N-E-Y-I-Y-L-W-K-K-K-Q-K-K-I-K-M-W-N-N-I-N-S-R-L-L-L-N-R-F-K-L-S-Q-L-D-D-Q-D-L-L-D-S-C-C-T-Y-K-Y-L-L-K-N-D-R-E-D-T-D-Y-V"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-F-Q-R-D-I-K-I-T-T-P-N-G-L-H-T-R-P-A-A-L-L-V-K-E-A-K-K-F-I-S-E-I-N-I-I-S-N-G-K-S-A-N-A-K-S-L-F-K-L-Q-T-L-G-L-V-Q-N-S-L-I-T-I-S-A-H-G-I-D-E-K-V-A-V-E-D-L-A-K-F-L-T-T-L-K"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-I-K-A-T-K-L-K-K-K-Y-D-K-L-K-I-A-K-W-S-F-L-G-I-L-I-I-L-F-I-L-S-N-H-Y-Y-I-K-H-S-N-I-F-Q-N-I-L-L-T-S-L-T-I-L-S-T-G-L-I-F-L-T-K-S-G-K-K-F-L-I-F-T-K-S-A-I-H-E-T-K-L-I-T-W-P-N-F-K-D-T-L-H-V-T-F-T-V-I-I-V-T-I-L-L-A-L-I-L-W-G-L-D-N-I-L-I-W-F-I-S-L-I-T-S-L-R-L"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase , probably by partially suppressing pausing In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho May be required to overcome a kinetic limitation of Rho to function at certain terminators Also involved in ribosomal RNA transcriptional antitermination ### SEQUENCE -M-Y-K-S-Y-K-K-R-W-Y-V-L-Q-A-F-S-G-F-E-G-R-I-A-Q-S-I-R-E-H-V-K-L-K-K-M-E-K-L-F-G-E-V-M-V-P-S-E-E-V-I-E-I-K-A-G-Q-R-K-K-S-E-Y-K-F-F-P-G-Y-V-L-I-Q-M-I-M-N-E-S-S-W-H-L-V-R-S-I-P-R-V-L-G-F-I-G-G-T-P-D-R-P-L-P-I-T-D-Q-E-V-N-T-I-I-N-K-L-K-Q-V-G-D-K-P-R-P-K-T-L-F-E-P-G-E-T-V-R-V-N-D-G-P-F-S-D-F-N-G-I-V-E-E-V-D-Y-E-K-N-R-L-K-V-S-V-S-I-F-G-R-S-T-P-V-E-L-D-F-S-Q-V-K-K-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-T-I-Q-A-Y-I-K-L-Q-V-S-A-G-T-A-N-P-S-P-P-I-G-P-A-L-G-Q-K-G-I-N-I-M-E-F-C-K-A-F-N-T-R-T-N-N-L-E-K-G-L-P-I-P-T-I-I-T-V-Y-S-D-K-S-F-S-F-I-T-K-T-P-P-A-S-V-L-L-K-K-A-A-G-I-T-K-G-S-S-K-P-N-Q-N-K-V-G-T-I-T-M-Q-Q-I-L-D-I-A-Q-I-K-K-I-D-M-T-G-S-N-I-D-N-I-S-K-S-I-I-G-T-A-N-S-I-G-L-I-I-A-E-G-T-N-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-M-L-D-F-K-K-K-K-E-L-V-T-Q-I-N-L-I-A-K-T-A-L-S-I-V-V-A-N-P-Q-G-I-K-S-N-D-I-T-Q-L-R-K-L-A-R-K-S-N-V-K-L-G-V-Y-R-N-T-L-L-N-L-G-I-K-N-T-P-F-E-C-L-K-N-I-L-I-G-P-T-L-I-A-Y-S-S-E-H-P-G-S-A-A-K-L-L-K-N-F-S-M-S-Q-S-S-N-P-N-F-K-I-L-G-A-V-F-E-G-K-A-I-S-G-S-N-I-N-S-L-A-D-I-P-T-F-N-E-A-L-R-R-F-I-I-I-A-K-E-I-S-A-G-K-L-L-R-I-L-V-S-I-K-N-I-K-E-N-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-I-T-K-E-Q-I-L-D-A-I-S-E-M-S-V-M-N-I-V-E-L-I-S-D-M-E-K-K-F-G-V-S-S-I-I-P-S-S-S-T-S-T-Q-N-I-E-T-A-E-A-K-T-E-F-D-V-L-L-K-S-I-G-G-N-K-V-S-V-I-K-A-V-R-S-A-T-G-L-G-L-K-E-A-K-D-L-V-E-S-A-P-T-I-I-K-E-R-I-T-Q-D-A-A-E-S-L-K-K-I-L-N-E-T-G-A-E-V-E-I-K"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-S-E-L-I-N-I-I-S-K-K-S-N-L-S-K-I-Q-I-K-N-I-L-E-I-T-L-T-A-I-I-Q-S-L-K-D-G-N-S-V-Q-L-V-G-F-G-T-F-K-V-N-N-R-A-A-R-I-G-R-N-P-Q-T-G-Q-T-I-H-I-S-A-T-K-T-P-V-F-I-S-G-K-T-F-K-T-A-I-K-T-I"} +{"text": "### FUNCTION Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle ### SEQUENCE -M-K-I-L-K-K-K-S-K-I-T-S-I-Q-I-I-S-G-K-Y-K-N-S-R-I-P-I-I-N-T-K-N-L-R-P-T-T-N-Y-I-R-E-T-L-F-N-W-I-S-N-E-K-I-K-K-S-H-C-L-D-C-F-S-G-S-G-A-L-G-I-E-A-V-S-R-Y-A-L-S-S-T-C-I-E-I-Q-K-K-A-I-F-F-L-K-K-I-L-I-K-L-S-I-T-N-V-H-V-I-R-A-N-T-I-Q-W-L-K-K-P-N-K-S-Y-D-I-I-F-L-D-P-P-F-K-T-T-L-L-K-Q-T-I-A-L-L-I-K-N-N-W-L-K-N-N-A-L-I-Y-I-E-Q-E-N-T-L-N-K-L-I-T-P-P-N-N-W-I-L-K-K-E-K-K-T-K-K-I-H-Y-S-L-Y-M-N-V-N-N-F"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-E-L-C-H-S-N-Q-L-K-I-G-L-K-I-I-Y-N-N-E-P-C-I-V-V-S-N-E-F-I-K-P-G-K-G-Q-A-F-F-R-V-R-L-K-N-L-L-N-K-K-L-I-D-K-T-C-K-Y-S-D-C-F-K-I-A-N-V-I-E-I-T-A-T-Y-M-F-T-D-K-K-V-W-T-F-M-D-K-K-S-F-E-Q-I-F-V-E-K-N-I-I-K-N-V-L-P-W-L-L-E-Q-H-D-Y-I-I-S-L-W-N-D-Q-P-I-S-I-V-Y-S-S-N-F-I-E-L-I-V-V-N-T-I-P-N-A-R-S-G-A-I-N-T-Y-S-K-L-A-L-L-N-T-G-V-T-I-K-V-P-I-F-I-Q-I-G-Q-I-I-K-V-D-T-R-T-S-E-Y-I-S-K-I-S"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-N-N-N-K-V-Y-S-L-N-V-V-S-F-E-K-I-I-F-N-D-F-V-K-K-I-Q-V-S-G-S-E-G-E-L-G-I-Y-P-G-H-L-Q-L-L-S-L-I-K-P-G-P-L-L-I-L-D-D-H-D-Y-Q-H-V-I-Y-I-S-G-G-I-I-E-V-Q-P-T-V-V-S-I-L-A-D-T-A-I-R-G-L-D-L-D-L-N-V-V-L-D-K-K-L-K-L-E-N-K-I-S-N-V-D-C-I-D-R-N-D-V-I-Q-Q-L-S-C-E-L-A-K-L-R-V-I-E-M-F-K-N-Q-Y-I-K-K-N-N"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-S-T-K-D-E-L-Q-L-Y-A-K-A-I-Y-N-C-A-I-S-N-H-Q-S-L-D-H-W-K-T-M-L-Q-L-M-A-N-I-L-N-N-E-I-I-K-N-L-I-S-K-A-Y-F-S-Q-H-V-I-S-L-F-I-D-L-C-C-N-K-V-N-Q-Y-G-I-N-L-I-K-I-L-A-E-N-K-R-L-M-L-L-E-K-L-Y-K-E-F-I-N-L-C-E-L-Y-Q-G-V-V-N-I-T-V-I-S-A-H-K-L-N-E-E-Y-I-S-K-I-N-I-M-L-K-K-R-F-F-K-K-I-N-V-T-Y-V-I-D-E-S-I-I-G-G-L-I-I-K-F-C-D-T-V-I-N-A-S-I-H-S-R-L-E-K-L-L-N-I-L-Q-Y"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-F-N-V-T-I-V-G-Q-A-I-S-F-V-L-F-V-F-F-C-M-K-Y-V-W-P-S-V-I-F-I-I-E-T-R-Q-K-E-I-K-D-S-L-T-F-I-E-N-S-K-K-E-L-N-I-F-K-E-N-S-K-N-E-I-K-I-I-K-K-N-A-S-K-I-I-D-S-A-I-Q-Q-K-T-Q-I-L-K-Q-A-Y-L-A-A-E-K-E-K-Q-T-I-L-K-Q-A-K-L-D-V-M-I-E-Y-Q-K-A-R-Y-E-L-R-Q-K-V-S-K-I-A-V-E-I-A-K-K-I-I-N-R-S-I-C-I-E-E-Q-N-S-I-I-S-S-L-I-K-K-I"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-D-F-L-G-M-M-K-Q-A-A-Q-L-Q-S-K-M-Q-E-M-Q-D-A-L-G-N-V-E-V-E-G-I-S-G-G-G-L-V-V-V-R-M-T-A-K-M-D-V-K-G-V-K-I-D-P-S-L-M-K-A-E-E-R-E-V-L-E-D-L-L-V-T-A-L-G-D-A-R-R-K-A-E-A-A-V-Q-E-K-M-Q-S-L-T-G-G-L-G-L-P-P-G-L-F-G-Q"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-G-A-V-A-G-P-E-I-E-R-L-V-Q-L-L-A-R-L-P-G-L-G-P-R-S-A-R-R-A-A-L-H-L-I-K-K-R-E-A-L-M-M-P-L-S-S-A-L-Q-V-A-L-D-K-V-Q-V-C-K-T-C-G-N-I-D-T-Q-N-P-C-T-V-C-T-D-P-K-R-D-P-A-I-I-V-V-V-A-D-V-A-D-L-W-A-L-E-R-A-N-A-T-Q-G-R-Y-H-V-L-G-A-T-L-S-P-L-D-G-V-G-P-Q-D-L-T-I-D-A-L-V-A-R-A-H-A-A-E-V-H-E-V-I-L-A-L-N-A-T-V-D-G-Q-T-T-A-H-Y-I-T-D-L-L-Q-D-A-N-V-K-V-T-R-L-A-H-G-V-P-V-G-G-E-L-D-Y-L-D-E-G-T-L-S-A-A-M-R-Q-R-T-L-F"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-E-K-V-P-M-T-S-A-G-F-A-A-L-G-E-E-L-K-K-R-Q-S-E-D-R-P-R-I-I-E-H-I-A-E-A-R-S-H-G-D-L-S-E-N-A-E-Y-H-A-A-K-E-E-Q-S-H-N-E-G-R-I-A-E-L-E-D-K-L-A-R-A-D-I-I-D-I-S-K-L-S-G-D-T-I-K-F-G-A-T-V-T-L-V-D-E-D-T-E-K-K-A-V-W-Q-I-V-G-E-V-E-A-D-A-K-K-G-R-I-S-I-T-S-P-L-A-R-A-L-I-G-K-K-K-G-S-T-V-E-V-N-A-P-G-G-A-K-A-Y-E-I-T-K-V-E-W-R"} +{"text": "### FUNCTION Has a post-transcriptional repressor function in flagellum biogenesis Associates with the 5'-UTR of fljK mRNA and promotes its degradation ### SEQUENCE -M-K-I-S-L-R-A-G-E-R-I-Y-I-N-G-A-V-L-R-V-D-R-K-V-S-V-E-L-V-N-D-V-M-F-L-L-E-G-Q-I-M-Q-A-S-D-A-T-T-A-M-R-Q-L-Y-F-I-V-Q-L-M-L-M-N-P-T-D-V-R-D-A-S-A-L-Y-G-Q-H-H-A-A-L-V-A-V-C-E-S-R-E-M-L-D-G-L-V-A-I-D-E-L-V-G-A-T-R-Y-F-E-A-L-K-R-I-R-A-L-F-P-V-E-Q-A-I-L-A-G-V-A-T-D-I-P-F-E-A-A"} +{"text": "### FUNCTION Required for coenzyme pyrroloquinoline quinone ### SEQUENCE -M-A-W-K-A-P-K-I-V-E-V-P-C-G-M-E-I-N-M-Y-V-S-A-T-R-K"} +{"text": "### FUNCTION Mediates sucrose transmembrane transport down a concentration gradient ### SEQUENCE -M-D-P-F-L-I-K-L-I-G-F-A-A-A-T-C-T-T-V-A-Y-A-P-Q-F-I-K-V-L-K-T-R-S-A-R-D-I-S-L-G-M-F-L-V-M-V-L-G-L-A-L-W-L-I-Y-G-L-L-S-G-D-A-P-L-I-A-S-N-A-V-T-M-L-L-A-G-G-I-L-V-M-K-L-R-Y-G"} +{"text": "### FUNCTION Aminoacyl carrier protein Can be charged with L-glycine via the formation of a thioester bond between the amino acid and the 4'-phosphopantetheinyl prosthetic group, catalyzed by the bll6282 ligase ### SEQUENCE -M-H-N-T-A-I-N-V-Q-N-R-V-L-S-V-V-R-S-V-L-Q-Q-N-A-I-S-A-D-V-H-P-E-S-R-L-V-D-I-G-L-S-S-M-G-M-V-E-L-M-L-K-V-E-A-E-F-D-L-I-L-P-Q-F-E-I-T-P-E-N-F-R-S-V-K-A-M-E-R-M-I-L-N-Q-L-G-S-G-S-G"} +{"text": "### FUNCTION Has a post-transcriptional repressor function in flagellum biogenesis Associates with the 5'-UTR of fljK mRNA and promotes its degradation ### SEQUENCE -M-A-L-K-V-E-L-K-P-H-E-R-I-I-V-G-N-S-V-I-T-N-T-D-Q-R-A-R-L-L-I-D-G-E-N-V-P-I-L-R-E-R-D-I-L-T-P-E-T-A-N-T-P-A-K-L-V-Y-L-A-V-Q-L-M-Y-I-S-P-D-P-Q-T-Q-H-G-T-Y-F-N-L-V-R-D-I-V-T-A-V-P-S-S-W-P-I-I-E-A-I-N-N-N-I-L-N-G-D-L-Y-R-A-L-K-D-A-R-K-L-I-A-Y-E-E-K-L-R-G-Q-Y-E-A-T-H-P-K-A-E-A-D-K-D-D-V-S-T-A-A"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-T-T-T-L-Y-T-S-D-H-E-W-L-A-I-E-G-D-V-A-T-V-G-I-T-D-Y-A-Q-S-Q-L-G-D-V-V-F-I-E-L-P-K-L-G-R-A-L-K-K-A-E-A-A-A-V-V-E-S-V-K-A-A-S-D-V-Y-A-P-V-T-G-E-V-L-E-T-N-D-A-L-A-A-E-P-A-L-V-N-S-D-A-Q-G-K-A-W-F-F-K-I-K-I-A-D-K-S-E-L-G-G-L-M-D-E-A-A-Y-K-A-H-T-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-T-G-Y-L-K-L-Q-V-P-A-G-A-A-N-P-S-P-P-I-G-P-A-L-G-Q-R-G-L-N-I-M-E-F-C-K-A-F-N-A-Q-T-Q-K-E-E-K-N-T-P-I-P-V-I-I-T-I-Y-A-D-R-S-F-T-F-E-M-K-T-P-P-M-S-Y-F-L-K-Q-A-A-K-I-Q-S-G-S-K-A-P-G-R-D-K-A-G-K-V-T-K-A-Q-V-R-E-I-A-E-K-K-M-K-D-L-N-C-D-T-I-E-S-A-M-K-M-V-E-G-S-A-R-S-M-G-L-E-V-A-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-T-A-N-R-K-E-L-A-V-E-R-A-A-K-K-E-A-V-E-Q-L-N-G-V-F-K-T-T-S-V-A-V-V-A-Q-Y-S-G-L-T-V-A-Q-M-Q-K-L-R-Q-Q-M-K-Q-A-G-A-S-V-K-V-S-K-N-R-L-A-K-I-A-L-E-G-T-D-V-V-A-I-G-P-M-L-K-G-P-T-V-I-A-T-S-N-D-P-V-A-A-P-K-V-A-I-E-F-A-K-A-N-E-K-F-V-I-V-G-G-S-M-G-K-T-V-L-N-V-D-G-V-K-A-L-A-S-L-P-S-L-D-E-L-R-G-K-I-V-G-L-I-V-A-P-A-T-K-L-A-Q-L-A-N-A-P-A-G-K-L-A-R-V-I-Q-A-H-A-S-K-G-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-D-L-Q-K-I-V-D-D-L-S-S-L-T-V-L-E-A-A-E-L-A-K-L-L-E-E-K-W-G-V-S-A-A-A-A-V-A-V-A-G-P-A-G-G-G-A-A-A-A-P-A-E-E-K-T-E-F-T-V-V-L-A-S-A-G-E-K-K-I-E-V-I-K-E-V-R-A-I-T-G-L-G-L-K-E-A-K-D-L-V-E-G-A-P-K-P-V-K-E-G-V-N-K-D-E-A-E-K-I-K-V-Q-L-E-K-A-G-A-K-V-E-L-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-I-A-Q-P-R-E-V-Q-K-S-R-K-K-V-P-A-L-Q-Q-S-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-V-R-L-T-N-G-F-E-V-I-G-Y-I-P-G-E-G-H-N-L-Q-E-H-S-V-V-M-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-L-R-G-V-L-D-T-Q-G-V-K-N-R-K-Q-R-R-S-K-Y-G-A-K-R-P-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-S-A-E-K-R-E-V-L-P-D-P-K-F-G-N-I-V-I-T-K-F-M-N-S-V-M-Y-A-G-K-K-S-V-A-E-G-I-V-Y-G-A-L-G-I-I-E-T-K-T-K-Q-N-P-L-G-V-F-E-Q-A-L-E-N-V-M-P-T-I-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-S-T-R-R-Q-A-L-G-I-R-W-L-I-S-A-A-R-E-R-N-E-K-T-M-T-E-R-L-S-A-E-L-L-D-A-S-N-N-R-G-N-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-R-A-F-S-H-Y-R-W"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-N-G-Q-N-I-R-I-R-L-K-A-F-D-H-R-I-L-D-T-S-T-R-E-I-V-N-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-I-E-K-F-T-V-N-R-S-P-H-V-D-K-K-S-R-E-Q-F-E-M-R-T-H-K-R-L-L-D-I-V-D-P-T-P-Q-T-V-D-A-L-M-K-L-D-L-A-A-G-V-D-V-E-I-K-L"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-K-N-I-E-P-R-H-Y-D-V-I-V-A-P-V-V-T-E-K-A-T-L-A-S-E-H-N-K-V-L-F-K-V-A-A-K-A-T-K-P-Q-I-K-E-A-I-E-K-L-F-D-V-K-V-K-S-V-N-T-L-V-R-K-G-K-T-K-V-F-R-G-N-L-G-S-Q-S-N-T-K-R-A-I-V-T-L-E-E-G-H-R-I-D-V-T-T-G-L"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-V-R-S-V-W-K-G-P-F-V-E-G-S-L-L-K-K-A-D-A-A-R-A-S-G-R-H-D-V-I-K-I-W-S-R-R-S-T-I-L-P-Q-F-V-G-L-T-F-G-V-Y-N-G-Q-K-H-V-P-V-A-V-N-E-E-M-V-G-H-K-F-G-E-F-S-P-T-R-T-F-H-G-H-S-G-D-K-K-A-K-K-A"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-K-P-K-R-E-R-S-L-A-E-N-E-A-K-A-V-A-R-M-L-R-V-S-P-Q-K-L-N-L-V-A-Q-L-I-R-G-R-K-A-A-A-A-L-A-D-L-Q-F-S-R-K-R-I-A-V-D-V-K-K-C-L-E-S-A-I-A-N-A-E-N-N-H-D-L-D-V-D-D-L-V-V-A-Q-A-F-V-G-N-G-L-V-M-K-R-F-A-A-R-G-R-G-R-S-G-R-V-Y-K-P-F-S-Q-L-T-I-I-V-R-Q-V-E-A-E-A-A-A-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-Q-P-K-K-T-K-F-R-K-A-H-K-G-R-I-H-G-V-A-S-S-G-A-T-L-A-F-G-Q-Y-G-L-K-A-T-E-P-E-R-V-T-A-R-Q-I-E-A-A-R-R-A-L-T-R-H-M-K-R-A-G-R-V-W-I-R-V-F-P-D-L-P-V-S-K-K-P-A-E-V-R-M-G-S-G-K-G-S-P-E-L-W-V-A-R-V-K-P-G-R-V-L-F-E-I-D-G-V-N-T-Q-T-A-R-E-A-L-T-L-A-A-A-K-L-P-I-K-T-R-F-V-E-R-I-A-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-T-L-Q-G-V-V-V-S-D-K-T-A-K-T-V-V-V-R-V-D-R-R-F-T-H-P-I-Y-K-K-T-I-R-R-S-K-N-Y-H-A-H-D-E-N-N-E-F-K-P-G-D-M-V-W-I-E-E-S-K-P-I-S-K-L-K-R-W-V-V-I-R-G-E-H-K-K-S-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-N-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-T-I-G-D-I-I-V-V-S-I-K-E-A-I-P-R-G-K-V-K-K-G-D-V-M-K-A-V-V-V-R-V-R-K-D-I-R-R-A-D-G-S-V-I-R-F-D-R-N-A-A-V-L-I-N-N-Q-S-E-P-V-G-T-R-I-F-G-P-V-P-R-E-L-R-A-K-N-H-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-K-G-D-K-V-V-V-L-T-G-R-D-K-G-R-T-G-E-V-F-E-V-R-P-D-A-G-T-A-L-V-R-G-I-N-M-V-K-R-H-Q-K-Q-T-Q-A-Q-E-G-G-I-I-S-K-E-A-P-I-Q-L-S-N-I-A-Y-V-G-K-D-G-K-P-T-R-V-G-F-K-I-L-A-D-G-K-K-V-R-I-A-K-S-S-G-A-E-I-D-G"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-E-A-A-Y-T-P-R-L-R-A-E-Y-D-A-K-I-R-T-A-M-T-E-K-F-G-Y-E-N-V-M-Q-V-P-R-L-D-K-V-V-L-N-M-G-V-G-D-S-V-N-D-R-K-K-A-E-T-A-A-A-E-L-T-Q-I-A-G-Q-K-A-I-V-T-Y-S-R-I-A-I-A-T-F-K-L-R-E-N-Q-P-I-G-C-K-V-T-L-R-K-A-R-M-Y-E-F-I-D-R-L-V-T-V-A-L-P-R-V-R-D-F-R-G-L-N-P-K-S-F-D-G-R-G-N-Y-S-L-G-I-K-E-H-I-I-F-P-E-I-D-F-D-K-V-T-E-A-R-G-M-D-I-T-V-C-T-T-A-K-T-D-E-E-A-R-A-L-L-T-A-F-N-F-P-F-R-Q"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-S-I-E-K-N-N-R-R-K-R-M-V-K-N-A-A-P-K-R-E-R-L-K-A-I-I-A-D-K-T-L-P-M-E-E-R-F-A-A-T-L-K-L-A-E-M-P-R-N-S-S-A-T-R-V-R-L-R-C-E-L-S-G-R-P-R-S-N-Y-R-K-N-K-L-S-R-I-A-L-R-E-L-G-S-K-G-M-V-P-G-L-V-K-S-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-T-H-D-P-I-S-D-L-I-T-R-I-R-N-A-Q-M-R-S-K-T-K-V-S-T-P-G-S-R-M-R-E-N-V-L-E-V-L-K-S-E-G-Y-I-R-G-Y-A-T-V-E-H-S-S-G-R-S-E-I-E-I-E-L-K-Y-F-D-G-E-P-V-I-R-E-I-E-R-V-S-K-P-G-R-R-V-Y-A-S-V-K-N-L-P-R-V-N-N-G-L-G-I-S-V-L-S-T-P-K-G-I-M-A-D-H-S-A-R-D-A-N-V-G-G-E-V-L-F-T-V-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-R-P-V-A-V-P-S-G-V-T-A-T-V-D-G-Q-T-V-K-M-K-G-P-K-G-Q-L-Q-F-V-V-H-D-D-V-E-V-K-L-E-S-G-Q-I-K-V-K-P-R-L-E-T-N-R-A-R-A-L-Y-G-T-A-R-A-Q-V-A-N-L-V-E-G-V-T-K-G-F-E-K-K-L-E-I-T-G-V-G-Y-R-A-A-M-Q-G-K-N-L-Q-L-A-L-G-Y-S-H-D-V-I-Y-T-I-P-E-G-I-T-I-T-V-P-K-P-T-E-I-T-V-T-G-S-D-I-Q-R-V-G-Q-V-A-A-E-I-R-S-Y-R-P-P-E-P-Y-K-G-K-G-V-K-Y-V-G-E-F-I-F-R-K-E-G-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-K-A-K-V-T-N-A-R-R-K-R-S-V-R-L-K-L-R-R-S-G-G-G-R-P-R-L-S-V-F-R-S-S-K-H-I-Y-A-Q-V-I-D-D-L-K-G-E-T-L-A-S-A-S-S-L-E-K-S-M-R-D-G-G-K-T-G-A-D-I-D-A-A-K-A-V-G-K-L-L-A-E-R-A-A-E-K-G-V-K-E-V-V-F-D-R-G-S-Y-L-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-S-G-L-S-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-E-R-E-Q-R-G-G-R-D-Q-R-G-G-G-R-E-R-K-E-R-E-E-R-D-S-E-F-V-D-K-L-V-H-I-N-R-V-A-K-V-V-K-G-G-K-R-F-G-F-A-A-L-V-V-I-G-D-Q-K-G-R-A-G-F-G-H-G-K-A-R-E-V-P-E-A-I-R-K-A-T-E-S-A-K-R-N-L-T-R-V-S-L-R-E-G-R-T-L-H-H-D-I-A-G-R-H-G-A-G-R-V-Y-L-R-A-A-P-A-G-T-G-I-I-A-G-G-P-M-R-A-V-F-E-T-L-G-V-Q-D-V-V-A-K-S-I-G-S-S-N-P-Y-N-M-V-R-A-T-F-D-A-L-K-H-Q-D-S-P-R-S-V-A-A-R-R-N-I-K-V-S-T-L-Q-S-R-R-I-G-G-D-A-E-A-A-A-D"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-S-D-I-A-D-N-A-G-S-R-K-K-R-M-R-V-G-R-G-I-G-S-G-K-G-K-Q-S-G-R-G-G-K-G-Q-T-A-R-S-G-V-R-I-K-G-F-E-G-G-Q-M-P-M-H-R-R-L-P-K-R-G-F-N-N-I-F-R-V-E-F-A-E-I-N-L-D-R-L-Q-E-A-V-D-A-K-K-I-D-A-G-S-V-V-N-V-E-A-L-V-K-G-G-V-L-R-R-A-K-G-G-L-R-L-L-G-R-G-E-L-K-S-K-L-N-I-E-V-H-G-A-T-K-T-A-I-A-A-V-E-K-A-G-G-S-V-K-I-L-A-P-A-K-E-E-G-E-A-A"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-T-N-K-R-V-L-I-A-L-Q-Y-I-H-G-I-G-Q-K-I-A-G-E-I-L-E-K-V-K-I-P-V-D-R-R-V-S-Q-L-S-D-A-E-V-L-Q-I-R-E-V-I-D-R-D-Y-L-V-E-G-D-L-R-R-E-V-G-I-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-H-T-N-A-R-T-R-K-G-P-A-K-A-I-A-G-K-K-K"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-N-D-E-N-R-S-G-S-P-T-G-P-N-T-S-V-I-T-K-V-K-P-K-T-K-R-P-N-L-Y-R-V-L-I-L-N-D-D-Y-T-P-M-E-F-V-V-H-V-L-E-K-F-F-Q-K-D-V-E-A-A-T-K-I-M-L-H-V-H-H-H-G-I-G-E-C-G-V-F-T-Y-E-I-A-E-T-K-V-T-Q-V-M-D-F-A-R-K-H-Q-H-P-L-Q-C-V-M-E-K-K"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-A-L-I-L-P-L-V-D-A-A-T-H-W-P-E-R-G-G-L-V-G-L-D-L-G-T-K-T-I-G-V-A-V-S-N-P-D-R-R-L-A-T-G-V-E-T-I-Q-R-K-A-F-K-Q-D-A-A-R-L-L-A-I-A-A-E-R-K-V-V-G-F-V-L-G-L-P-I-N-M-D-G-S-E-G-P-R-A-Q-S-T-R-A-F-A-R-N-L-A-N-L-T-T-L-P-I-G-L-W-D-E-R-L-S-T-A-A-V-E-R-E-L-I-G-M-D-V-S-R-A-K-R-A-E-V-I-D-E-H-A-A-I-F-I-L-Q-G-A-L-D-R-L-A-N-L-R-T-G-N-G"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-R-E-F-A-M-K-G-N-V-V-D-L-A-V-G-V-I-I-G-A-A-F-G-A-I-V-T-S-L-V-G-D-V-I-M-P-L-I-G-A-V-T-G-G-L-D-F-S-N-Y-F-T-P-L-S-K-A-V-T-A-T-N-L-A-D-A-K-K-Q-G-A-V-L-A-W-G-S-F-L-T-L-T-I-N-F-I-I-I-A-F-V-L-F-L-V-I-R-A-I-N-T-L-K-R-K-E-E-A-A-P-A-A-P-P-K-P-S-A-E-V-E-L-L-T-E-I-R-D-L-L-K-K-S"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-N-C-N-S-L-D-T-Q-V-K-D-S-R-P-T-E-D-S-S-V-I-R-R-R-R-V-C-V-A-C-N-F-R-F-T-T-F-E-R-V-Q-L-R-E-L-T-V-I-K-R-N-G-R-R-V-P-F-D-R-D-K-L-M-R-S-V-Q-I-S-L-R-K-R-Q-V-E-P-E-R-V-E-K-M-V-S-T-I-V-R-E-L-E-T-G-G-E-A-E-I-S-S-E-V-I-G-E-T-V-M-E-H-L-R-T-L-D-D-V-A-Y-V-R-F-A-S-V-Y-R-N-F-R-E-A-K-D-F-A-D-V-L-G-E-L-S-G-E-E-E-A-R-L-A-A-I-R-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-A-D-A-R-R-A-P-L-K-D-Q-T-D-I-S-G-A-R-A-L-I-V-E-A-R-F-Y-D-D-L-Q-D-A-L-L-D-G-A-V-A-E-L-K-A-A-G-L-T-H-D-V-I-T-V-P-G-A-L-E-I-P-A-A-V-A-I-A-V-D-A-A-A-A-N-G-K-P-Y-D-A-V-I-A-L-G-C-V-I-R-G-D-T-I-H-F-E-I-V-S-Q-E-S-S-R-A-L-M-D-L-A-V-S-R-K-L-P-L-G-N-G-I-L-T-V-N-T-E-A-Q-A-W-A-R-A-R-A-S-E-L-N-K-G-G-D-A-A-R-A-A-L-A-M-L-R-I-K-R-R-L-A-R-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-A-D-N-N-K-K-P-A-G-L-T-E-K-K-A-N-R-R-G-A-A-R-L-A-A-V-Q-A-L-Y-Q-M-D-I-A-G-A-G-I-N-D-I-F-A-E-F-E-S-H-W-L-G-N-E-V-E-G-D-T-Y-L-P-A-E-A-A-F-F-R-D-V-V-S-G-V-V-R-D-Q-K-K-L-D-P-L-I-D-E-A-L-S-K-G-W-P-L-K-R-I-E-A-I-L-R-A-V-L-R-A-G-A-Y-E-L-Q-H-R-K-D-V-P-G-R-V-V-V-S-E-Y-V-D-V-A-N-A-F-V-D-R-E-E-T-G-M-V-N-A-V-L-D-Q-I-G-R-Q-F-R-G-D-E-F-G-R-G"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-S-A-K-P-A-E-V-T-K-K-W-V-L-I-D-A-K-G-L-V-V-G-R-L-A-T-I-V-A-M-R-L-R-G-K-H-L-P-T-Y-T-P-H-V-D-C-G-D-N-V-I-I-I-N-A-Q-H-A-V-L-T-G-R-K-R-E-Q-K-T-Y-Y-K-H-T-G-Y-V-G-H-V-K-E-R-T-A-R-Q-I-L-E-G-K-H-P-E-R-V-L-E-K-A-V-E-R-M-I-P-R-G-P-L-G-R-V-Q-M-G-N-L-R-V-Y-G-G-A-D-H-P-H-E-A-Q-Q-P-E-K-I-D-I-A-K-L-N-R-K-N-T-R-A-A"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-M-P-T-G-N-F-D-L-N-E-V-K-R-R-M-Q-G-A-V-Q-S-L-K-H-E-L-G-G-L-R-T-G-R-A-S-A-S-M-L-D-P-V-Q-V-E-A-Y-G-S-H-M-P-L-N-Q-L-A-T-V-S-V-P-E-P-R-L-I-S-V-Q-V-W-D-K-S-M-V-K-A-V-E-K-A-I-V-D-S-N-L-G-L-S-P-A-T-E-G-Q-V-L-R-L-R-I-P-E-L-N-E-E-R-R-K-E-L-V-K-V-A-H-K-Y-A-E-A-A-K-V-A-A-R-H-V-R-R-D-G-L-D-V-L-K-K-L-E-K-N-H-E-M-S-E-D-D-Q-K-R-H-A-D-E-V-Q-K-V-T-D-G-T-I-A-E-I-D-Q-L-L-A-A-K-E-K-E-I-L-T-V"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-L-S-I-W-H-W-I-L-V-I-A-V-V-L-L-L-F-G-R-G-K-I-S-D-L-M-G-D-V-A-Q-G-I-K-A-F-K-K-G-M-Q-D-D-D-K-P-A-D-K-P-E-P-A-K-S-I-E-H-N-A-A-P-T-A-A-R-S-D-V-G-S-K-A-V"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-W-S-E-L-V-L-I-G-V-V-A-L-I-A-I-G-P-K-E-L-P-G-V-L-R-M-V-G-Q-W-M-G-K-A-R-K-M-A-A-E-F-Q-G-Q-F-Q-E-A-M-R-E-A-E-M-A-D-L-K-K-S-F-D-E-V-K-E-A-A-S-G-F-A-G-N-N-L-M-T-S-L-Q-K-D-V-S-D-A-L-R-V-D-A-L-D-K-P-A-E-T-S-S-T-T-A-I-E-A-P-A-T-S-S-E-A-L-T-T-P-T-T-P-E-A-P-T-P-E-T-F-V-E-A-E-A-H-A-A-V-N-E-P-L-A-I-T-R-E-V-E-Q-A-P-V-V-A-Q-D-T-A-P-S-E-A-I-K-D-A-K-A-S"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-V-N-K-V-I-L-V-G-N-L-G-K-D-P-E-I-R-R-T-Q-D-G-R-P-I-A-N-L-S-I-A-T-S-E-T-W-R-D-K-N-S-G-E-R-K-E-K-T-E-W-H-R-V-V-I-F-N-E-G-L-C-K-V-A-E-Q-Y-L-K-K-G-A-K-V-Y-I-E-G-A-L-Q-T-R-K-W-T-D-Q-S-G-V-E-K-Y-S-T-E-V-V-L-Q-G-F-N-S-T-L-T-M-L-D-G-R-G-G-G-G-G-G-S-F-G-E-E-P-G-G-D-F-G-S-S-G-P-V-S-S-A-P-R-R-A-V-A-A-G-G-G-G-R-N-S-D-M-D-D-D-I-P-F"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-A-D-R-A-Q-N-L-Q-D-T-F-L-N-H-V-R-K-T-K-T-P-L-T-I-F-L-V-N-G-V-K-L-Q-G-I-V-T-W-F-D-N-F-C-L-L-L-R-R-D-G-H-S-Q-L-V-Y-K-H-A-I-S-T-I-M-P-G-A-P-I-Q-L-F-E-G-G-E-D-Q-P-A"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-R-V-I-A-S-S-I-R-K-G-N-V-I-E-Q-D-G-K-L-Y-V-V-V-S-A-E-N-I-H-P-G-K-G-T-P-V-S-Q-I-E-M-R-R-I-S-D-G-V-K-I-S-E-R-Y-K-T-T-D-Q-V-E-K-A-T-I-E-E-R-N-F-T-F-L-Y-E-D-G-D-G-Y-H-F-M-N-P-E-T-Y-D-Q-V-Q-V-S-K-D-V-V-G-D-A-A-A-Y-L-Q-P-D-M-T-V-K-L-S-T-H-D-V-N-V-V-S-L-A-L-P-Q-R-V-T-L-E-V-V-E-T-E-P-V-T-K-G-Q-T-A-S-S-S-Y-K-P-A-V-L-S-N-G-I-R-T-T-V-P-P-H-I-A-V-G-T-R-I-V-V-M-T-E-D-G-S-Y-S-E-R-A-K-D"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-G-L-L-R-L-L-R-G-N-K-A-S-A-P-V-A-R-E-R-L-Q-I-L-L-A-H-E-R-G-M-R-G-Q-P-D-L-L-G-V-L-R-E-E-I-L-A-V-V-S-K-H-V-T-L-D-P-T-K-V-I-V-R-L-E-R-G-D-E-V-S-T-L-E-V-D-I-E-V-P-N-D-L-E-R-K-R-V-A-V-A"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-D-I-G-E-R-V-K-K-I-V-V-E-H-L-G-V-E-P-E-K-V-V-D-A-A-S-F-I-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-F-E-E-E-F-G-C-E-I-P-D-D-A-A-E-T-I-L-T-V-G-D-A-T-K-F-L-E-K-N-A-K-S"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-L-Y-E-H-V-F-L-A-R-Q-D-A-S-P-Q-Q-V-E-E-L-T-A-Q-M-T-G-I-V-E-G-L-G-G-K-V-T-K-T-E-N-W-G-V-R-S-L-T-Y-R-M-N-K-N-R-K-A-H-F-V-L-L-N-I-D-A-P-S-A-A-I-A-E-I-E-R-Q-E-R-I-S-E-D-V-I-R-Y-L-S-V-R-V-E-E-L-E-E-G-P-S-A-M-M-R-K-A-D-R-D-R-E-R-D-D-R-G-G-G-F-R-G-E-R-E-G-G-F-R-G-D-R-E-G-G-F-R-G-G-D-R-D-G-G-G-F-R-G-D-R-G-P-R-R-P-R-E-E-A-E-T-A-T-D-G-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-E-A-G-A-R-R-P-F-F-R-R-R-K-S-C-P-F-T-G-A-N-A-P-K-I-D-Y-K-D-S-K-L-L-M-R-Y-V-S-E-R-G-K-I-V-P-S-R-I-T-A-V-S-A-K-K-Q-R-E-L-A-R-A-I-K-R-A-R-F-L-G-L-L-P-Y-V-I-R"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-E-N-T-Q-V-D-V-S-R-L-T-F-E-R-A-I-E-E-L-E-T-I-V-K-R-L-E-D-G-K-V-P-L-E-E-S-V-T-I-Y-E-R-G-E-A-L-K-R-R-C-E-E-L-L-R-Q-A-E-A-R-V-D-K-I-T-T-D-A-S-G-Q-A-T-G-T-A-P-L-D-V-Q"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-R-M-G-G-S-F-V-V-L-S-G-V-I-A-I-V-V-G-S-V-L-G-G-C-A-R-Y-F-I-S-G-A-V-A-R-R-L-G-E-T-F-P-W-G-T-M-T-I-N-V-T-G-A-F-L-I-G-I-F-G-A-L-A-T-H-P-G-S-M-F-A-S-P-N-P-W-L-F-A-V-T-G-F-L-G-C-Y-T-T-V-S-S-F-S-L-Q-T-L-T-L-A-R-N-G-E-P-M-H-A-L-G-N-V-A-F-S-V-G-L-C-L-A-A-V-S-C-G-F-L-L-A-D-G-L-G-G"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-V-P-S-S-A-E-R-W-R-S-A-M-L-Y-A-W-V-S-A-G-S-V-V-G-G-L-T-R-Y-L-V-G-L-A-L-D-T-G-P-G-F-P-F-A-T-L-F-I-N-A-T-G-S-L-I-I-G-F-Y-A-T-L-T-G-P-D-G-R-M-L-A-R-P-E-H-R-Q-F-V-M-T-G-F-C-G-G-Y-T-T-F-S-A-F-S-L-E-T-F-R-L-F-H-G-G-M-K-Y-I-A-L-A-Y-V-A-S-S-V-V-C-W-L-V-S-V-W-L-G-H-I-M-A-S-R-Y-N-R-L-K-R-S"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-N-D-A-V-T-K-P-K-T-R-T-K-T-K-V-E-R-P-K-L-H-K-V-I-L-I-N-D-D-Y-T-P-R-E-F-V-T-M-I-L-K-A-E-F-R-M-T-E-D-Q-A-Y-K-V-M-I-T-A-H-K-L-G-A-C-V-V-A-V-F-T-R-D-V-A-E-T-K-A-T-R-A-T-D-A-G-R-A-K-G-Y-P-L-L-F-T-T-E-P-E-E"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-R-S-L-H-D-I-E-A-T-D-H-F-V-D-W-G-N-S-T-S-H-R-L-L-T-D-K-D-G-M-G-F-S-I-C-H-T-I-V-R-A-N-T-V-S-L-L-Q-Y-R-N-H-L-E-A-C-F-C-I-G-G-E-G-E-V-E-D-M-D-G-N-V-F-P-I-R-R-G-D-M-Y-V-L-D-K-H-D-K-H-L-L-R-G-G-P-D-K-D-M-I-L-V-S-I-F-N-P-P-L-T-G-T-E-R-H-K-L-D-D-P-A-G-S-T-Y"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-E-I-H-P-D-Y-H-T-I-K-V-V-M-T-D-G-T-E-Y-L-T-R-S-T-W-G-K-E-G-D-T-L-N-L-D-I-D-P-K-S-H-P-A-W-T-G-G-N-A-Q-I-M-D-R-G-G-R-V-S-R-F-Q-K-K-F-S-G-F-L-K-K-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-L-I-Q-F-E-G-L-V-T-E-I-L-P-D-A-R-Y-R-V-Q-L-D-A-G-H-E-I-V-A-Y-T-A-G-K-M-K-K-N-R-I-K-T-L-A-G-D-R-V-T-V-E-M-S-P-Y-D-L-E-K-G-R-L-I-F-R-H-K-D-E-R-P-A-T-S-G-G-P-P-R-G-G-A-Q-R-G-G-Q-F-R-R-R"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-D-D-Q-V-K-M-P-T-G-P-L-K-T-C-P-I-C-G-K-P-A-V-Q-A-T-H-P-F-C-S-S-R-C-R-D-V-D-L-N-R-W-L-K-G-S-Y-V-I-P-G-R-D-D-E-V-D-D-V-E"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-F-F-D-P-E-T-W-V-A-I-A-F-V-I-L-M-V-V-F-G-Y-L-G-V-F-K-S-A-M-T-A-L-D-H-R-A-A-R-I-K-A-E-L-D-D-A-T-R-L-K-Q-E-A-A-K-V-L-A-D-Y-K-A-R-S-A-T-A-E-R-E-A-A-D-I-I-A-N-A-K-V-E-A-E-R-I-A-T-E-A-K-A-K-M-E-D-F-V-A-R-R-T-K-T-A-E-S-K-I-A-L-A-E-A-Q-A-V-A-D-V-R-A-A-A-A-E-A-A-V-Q-A-A-S-T-I-L-S-Q-S-V-K-G-Q-V-A-D-D-L-L-A-K-S-I-S-E-V-R-Q-K-L-N"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-T-S-A-K-K-A-T-R-K-I-A-R-R-T-A-V-N-K-S-R-R-T-Q-M-R-G-A-V-R-N-V-E-E-A-I-K-T-G-D-R-A-A-A-V-K-A-L-A-N-A-E-P-A-L-M-R-A-A-Q-R-N-I-I-H-K-N-N-A-S-R-K-V-S-R-L-T-A-Q-I-A-K-L-A-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-G-A-D-A-S-A-F-S-F-R-T-K-T-M-S-H-P-N-L-P-M-T-E-V-L-V-V-A-D-C-W-Q-R-E-P-D-S-E-A-V-I-Q-R-A-V-A-A-A-A-E-S-V-D-E-D-V-A-E-A-E-V-A-V-M-L-T-D-D-A-G-I-R-T-L-N-S-N-W-R-G-I-D-K-P-T-N-V-L-S-F-P-A-L-Q-P-E-G-E-W-K-E-G-D-A-P-R-M-L-G-D-I-A-I-A-Y-E-T-M-R-R-E-A-D-E-E-K-K-P-F-D-H-H-L-S-H-L-A-V-H-G-F-L-H-L-I-G-Y-D-H-E-N-D-D-D-A-E-E-M-E-A-L-E-T-Q-I-L-A-H-L-G-I-P-D-P-Y-A-D-R-P-G-T-H"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-R-H-H-Q-K-K-S-S-A-S-G-G-G-S-Q-R-Q-L-R-V-G-E-Q-V-R-H-A-M-A-E-I-L-A-Q-G-N-V-H-D-A-D-L-E-G-H-I-V-T-V-P-E-V-R-M-S-P-D-L-K-L-A-T-I-Y-V-M-P-L-G-G-R-D-T-E-I-V-I-A-A-L-E-R-N-K-K-F-L-R-G-E-V-A-R-R-V-N-L-K-F-A-P-D-V-R-F-R-V-D-E-R-F-D-E-A-E-R-I-E-K-L-L-R-T-P-A-V-Q-K-D-L-E-Q-D-P-D-S-D-R-E-E-E-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-I-A-A-E-R-K-A-E-V-I-K-T-N-A-T-K-A-G-D-T-G-S-P-E-V-Q-V-A-I-L-S-E-R-I-N-N-L-T-S-H-F-K-T-H-V-K-D-N-H-S-R-R-G-L-L-K-L-V-S-T-R-R-S-L-L-D-Y-L-K-K-R-D-E-A-R-Y-K-A-L-L-E-K-H-N-I-R-R"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-R-R-P-N-K-A-P-P-A-A-S-K-D-G-P-R-I-N-D-D-I-R-N-A-Q-I-Q-L-I-D-Q-T-G-D-N-K-G-T-V-E-T-V-V-A-I-K-M-A-Q-E-A-G-M-D-L-V-E-I-S-P-N-T-S-P-P-V-C-K-I-M-D-Y-G-K-Y-K-Y-S-A-Q-K-K-A-A-E-A-R-K-R-Q-K-T-V-E-I-K-E-I-K-L-R-P-M-I-D-D-H-D-Y-D-V-K-M-R-A-M-Q-R-F-F-E-E-G-D-K-V-K-I-T-L-R-Y-R-G-R-E-M-A-H-Q-E-I-G-T-K-L-L-D-K-I-K-T-D-V-A-E-L-A-K-V-E-Q-D-A-R-F-E-G-R-Q-V-V-M-V-L-A-P-R"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-S-R-V-K-R-G-V-T-A-H-A-K-H-K-K-V-Y-K-A-A-K-G-F-Y-G-R-R-K-N-T-I-R-A-A-K-P-A-V-E-K-A-Q-Q-Y-A-F-R-D-R-K-R-K-K-R-T-F-R-A-L-W-I-Q-R-L-N-A-A-V-R-P-F-G-L-T-Y-S-R-F-I-D-G-L-A-K-S-G-I-T-V-D-R-K-V-L-S-D-L-A-I-N-E-P-A-S-F-Q-A-I-A-E-K-A-K-A-A-L-A-A"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-Q-R-I-T-I-T-I-E-D-D-L-L-A-E-I-D-A-A-A-A-A-R-G-Y-Q-N-R-S-E-I-I-R-D-L-A-R-A-G-L-Q-Q-T-S-E-D-T-A-Q-T-G-P-C-V-A-G-L-V-Y-V-Y-D-H-A-A-R-D-L-S-K-R-L-V-Q-E-F-H-G-H-H-D-L-A-L-A-T-L-H-V-H-L-D-D-N-N-C-M-E-M-T-A-L-R-G-A-A-D-E-V-R-H-F-A-D-H-I-I-A-E-R-G-V-R-Y-G-R-V-V-M-I-P-T-G-E-G-K-P-A-K-A-R-K-H-G-H-R-H-E"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-T-N-G-N-G-T-P-P-E-A-A-P-A-P-Q-L-N-V-L-A-Q-Y-T-K-D-L-S-F-E-N-P-N-A-P-S-S-L-Q-Q-Q-G-Q-P-P-Q-I-N-I-Q-I-N-V-G-A-N-N-L-S-E-Q-E-F-E-V-T-L-S-V-E-G-K-A-E-T-A-G-K-V-M-F-S-F-E-L-A-Y-A-G-V-F-R-I-V-N-V-P-K-E-N-L-H-P-L-V-M-I-E-C-P-R-L-L-F-P-F-A-R-E-I-I-A-T-A-V-R-D-G-G-F-P-P-L-M-L-D-P-V-D-F-V-G-L-Y-R-Q-N-M-E-R-Q-M-A-A-G-G-Q-A-G-Q-A"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-L-I-K-Q-L-E-Q-E-Q-F-D-K-L-S-A-G-K-D-I-P-E-F-G-P-G-D-T-V-I-V-N-V-K-V-V-E-G-D-R-T-R-V-Q-A-Y-E-G-V-C-I-G-R-S-G-G-G-L-N-E-S-F-T-V-R-K-I-S-Y-G-E-G-V-E-R-V-F-P-V-M-S-P-M-I-D-S-I-K-V-V-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-N-L-R-G-K-S-A-R-I-V-E-K-Q-D-R-Q-A-A-V-G-E"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-A-L-V-C-V-A-R-I-G-A-A-H-G-V-R-G-A-V-K-L-W-T-F-T-E-D-P-F-A-I-K-R-Y-G-P-L-L-S-K-D-G-K-R-Q-F-E-V-A-Q-A-R-E-A-K-D-H-L-V-A-T-F-K-G-V-T-T-R-D-E-A-E-R-L-N-G-I-E-L-Y-V-A-R-E-K-L-P-A-T-D-E-D-E-Y-Y-H-T-D-L-I-G-L-A-A-V-T-T-D-G-E-P-L-G-R-V-L-A-I-H-N-F-G-A-G-D-I-I-E-I-A-P-P-K-G-A-S-L-L-L-P-F-S-N-A-V-V-P-E-V-D-V-A-G-G-R-V-V-V-A-L-P-Q-E-I-A-G-D-E-A-E-E-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-A-E-D-T-S-V-S-G-V-S-G-R-Y-A-T-A-L-F-E-L-A-R-D-Q-K-A-V-D-E-V-K-A-D-L-D-R-F-E-A-L-L-G-E-S-A-D-L-K-R-L-V-R-S-P-V-F-A-A-D-A-Q-S-R-A-L-T-A-V-L-D-K-V-G-I-A-G-I-S-A-N-F-L-K-V-L-T-A-N-R-R-L-F-V-V-A-D-V-I-R-A-Y-R-A-L-V-A-K-F-K-G-E-A-T-A-D-V-T-V-A-E-A-L-S-D-K-N-L-D-A-L-K-V-A-L-K-S-V-T-G-K-D-V-A-L-N-V-K-V-D-P-S-I-I-G-G-L-V-V-K-L-G-S-R-M-V-D-G-S-L-R-T-K-L-N-S-I-K-H-A-M-K-E-A-G"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-A-R-Y-E-D-L-P-Y-R-T-C-V-G-V-M-L-I-N-A-K-G-L-V-F-I-G-R-R-A-G-G-I-E-H-I-D-D-T-H-V-W-Q-M-P-Q-G-G-V-D-P-G-E-D-T-W-A-A-A-K-R-E-L-Y-E-E-T-S-V-R-S-V-E-R-L-G-E-V-P-D-W-L-I-Y-D-I-P-R-T-V-A-G-R-A-W-K-G-R-Y-R-G-Q-R-Q-K-W-F-A-V-R-F-T-G-K-D-S-E-I-N-V-E-N-P-G-G-G-H-K-A-E-F-V-S-W-R-W-E-P-M-K-N-L-P-G-L-I-I-P-F-K-R-P-V-Y-E-R-V-V-K-E-F-S-A-L-A-E-E"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-R-V-A-V-I-A-V-G-R-L-K-Q-G-P-E-R-E-L-A-D-R-Y-F-E-R-F-D-E-A-G-R-K-L-G-F-R-E-L-S-I-H-E-I-P-E-S-R-A-R-D-A-A-T-R-M-A-E-E-A-A-A-I-G-A-Y-I-P-D-K-S-I-L-V-A-L-D-E-R-G-Q-N-L-D-S-T-V-F-A-R-H-L-G-R-W-R-D-E-G-A-G-H-T-I-F-V-I-G-G-A-D-G-L-S-P-E-L-R-R-K-A-K-L-A-I-A-F-G-S-A-T-W-P-H-Q-M-V-R-V-M-L-L-E-Q-L-Y-R-A-A-T-I-L-A-G-H-P-Y-H-R-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-I-K-T-G-G-R-Q-Y-R-V-A-P-D-D-V-L-E-V-G-K-I-E-G-E-V-G-S-I-V-Q-L-N-E-V-L-V-V-G-G-D-T-P-I-L-G-L-P-T-V-A-G-A-S-V-A-V-E-V-L-D-H-K-R-G-P-K-V-I-A-F-K-K-R-R-R-K-N-S-R-R-K-R-G-Y-R-D-E-I-T-V-L-R-V-S-E-I-L-T-D-N-A-K-P-T-K-G-P-R-P-K-K-E-K-V-A-K-E-A-T-K-E-D-A-A-A"} +{"text": "### FUNCTION Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'--3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism ### SEQUENCE -M-E-D-L-S-F-R-H-P-V-R-A-R-A-D-G-A-R-R-S-A-I-V-G-I-V-A-S-G-N-L-E-V-L-V-E-R-V-L-P-D-A-E-C-A-I-D-I-K-T-A-A-V-G-F-G-E-V-W-R-A-V-I-G-D-F-V-E-R-Y-S-P-G-G-L-K-F-S-I-N-D-G-G-A-R-P-D-T-V-S-L-R-L-A-Q-A-V-R-S-I-A-E-N-G-Q"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-K-S-I-E-V-K-G-T-A-R-T-I-A-E-R-S-S-E-Q-A-R-A-L-K-E-I-R-K-N-G-G-V-P-C-V-L-Y-G-A-G-E-V-V-H-F-T-V-T-N-E-G-L-R-N-L-V-Y-T-P-H-I-Y-V-V-D-L-D-I-D-G-K-K-V-N-A-I-L-K-D-I-Q-F-H-P-V-K-D-N-I-L-H-V-D-F-Y-Q-I-D-E-A-K-P-I-V-M-E-V-P-V-Q-L-E-G-L-A-E-G-V-K-A-G-G-K-L-A-L-Q-M-R-K-I-K-V-K-A-L-Y-N-V-I-P-E-K-L-T-V-N-V-S-H-L-G-L-G-K-T-V-K-V-G-E-L-S-F-E-G-L-E-L-I-S-A-K-E-A-V-V-C-A-V-K-L-T-R-A-A-R-G-A-A-A-A-A-G-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-I-K-Y-L-I-V-G-L-G-N-I-G-P-E-Y-H-E-T-R-H-N-I-G-F-M-T-V-E-A-L-A-R-I-N-N-A-P-P-F-I-D-G-R-Y-G-F-T-T-S-F-S-I-K-G-R-Q-L-I-L-L-K-P-S-T-F-M-N-L-S-G-L-A-V-R-Y-W-M-Q-K-E-N-I-P-L-E-N-V-L-I-V-V-D-D-L-A-L-P-F-G-T-L-R-L-K-G-K-G-S-D-A-G-H-N-G-L-K-H-I-A-A-I-L-G-T-Q-N-Y-A-R-L-R-F-G-I-G-N-D-F-P-K-G-G-Q-I-D-Y-V-L-G-H-F-T-D-E-D-R-K-T-M-D-E-R-L-E-T-A-G-E-I-I-K-S-F-C-L-A-G-I-D-I-T-M-N-Q-F-N-K-K"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-K-T-L-L-F-I-G-M-G-S-F-T-G-G-V-L-R-Y-L-I-S-R-Y-V-Q-N-F-L-T-P-S-F-P-L-G-T-L-L-V-N-V-L-G-C-F-A-I-G-L-F-Y-G-L-F-E-R-G-N-L-M-N-P-N-L-R-M-F-L-T-V-G-F-C-G-G-F-T-T-F-S-T-F-M-N-E-N-F-Q-L-I-K-D-D-N-F-F-Y-L-S-L-Y-V-G-L-S-L-F-V-G-F-I-M-L-Y-L-G-Y-S-L-V-K-Q"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-T-G-L-E-I-W-L-L-A-I-G-L-A-M-D-C-F-A-V-S-I-A-S-G-I-I-L-K-R-T-Q-W-R-P-M-L-V-M-A-L-A-F-G-L-F-Q-A-L-M-P-F-I-G-W-M-F-A-K-T-F-S-H-L-I-E-S-V-D-H-W-I-A-F-A-I-L-A-F-L-G-G-R-M-I-L-E-S-F-K-D-E-D-C-R-Q-T-F-N-P-A-S-P-K-V-V-F-T-M-A-I-A-T-S-I-D-A-L-A-I-G-I-S-F-A-L-L-G-I-N-N-Y-T-E-I-L-S-P-I-L-I-I-G-F-V-S-F-V-M-S-L-I-G-L-Y-F-G-I-K-C-G-C-G-C-A-R-K-L-K-A-E-L-W-G-G-I-I-L-V-A-I-G-L-K-I-L-I-E-H-L-F-L-Q"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-E-I-N-G-Q-Q-F-K-A-E-A-G-Q-K-L-F-V-H-H-I-E-G-A-E-N-G-S-T-V-E-F-E-K-V-L-L-V-D-K-D-G-N-V-T-V-G-A-P-T-V-E-G-A-K-V-V-C-Q-V-I-S-N-L-V-K-G-D-K-V-L-V-F-H-K-K-R-R-K-G-Y-R-K-L-N-G-H-R-Q-Q-F-T-E-L-T-I-T-E-V-V-A"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-G-K-S-T-F-L-Q-D-F-K-A-F-A-M-K-G-N-V-I-D-M-A-V-G-V-V-I-G-G-A-F-G-K-I-V-S-S-L-V-A-N-V-I-M-P-P-I-G-L-L-V-G-G-V-N-F-T-D-L-K-W-V-M-K-A-A-E-V-G-A-D-G-K-E-I-A-P-A-V-S-L-D-Y-G-Q-F-L-Q-A-T-F-D-F-L-I-I-A-F-A-I-F-L-F-I-R-L-I-T-K-L-T-T-K-K-A-A-E-E-A-P-A-A-P-P-A-P-P-A-P-T-K-E-E-V-L-L-T-E-I-R-D-L-L-K-E-K-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-F-G-I-V-V-S-E-W-N-F-N-I-T-G-A-L-L-N-G-A-V-N-T-L-K-K-H-G-V-K-D-E-N-I-L-V-K-T-V-P-G-S-F-E-L-T-F-G-A-N-Q-M-M-E-N-C-D-V-D-A-I-I-A-I-G-C-V-I-K-G-D-T-P-H-F-D-Y-V-C-M-G-A-T-Q-G-I-T-E-L-N-A-T-G-D-I-P-V-I-Y-G-L-I-T-T-N-T-M-E-Q-A-E-D-R-A-G-G-K-L-G-N-K-G-D-E-C-A-I-S-A-I-K-M-I-D-F-V-W-S-L-N-K"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-K-K-A-N-R-L-D-A-I-K-M-I-I-S-S-K-E-V-G-S-Q-E-E-L-L-Q-E-L-N-R-E-G-F-E-L-T-Q-A-T-L-S-R-D-L-K-Q-L-K-V-A-K-A-A-S-M-N-G-K-Y-V-Y-V-L-P-N-N-I-M-Y-K-R-S-T-D-Q-S-A-G-E-M-L-R-N-N-G-F-I-S-L-Q-F-S-G-N-I-A-V-I-R-T-R-P-G-Y-A-S-S-M-A-Y-D-I-D-N-N-E-F-S-E-I-L-G-T-I-A-G-D-D-T-I-M-L-V-L-R-E-G-V-A-T-S-K-V-R-Q-L-L-S-L-I-I-P-N-I-E"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-N-A-Q-D-I-K-N-G-T-C-I-R-M-D-G-K-L-Y-F-C-I-E-F-L-H-V-K-P-G-K-G-N-T-F-M-R-T-K-L-K-D-V-V-S-G-Y-V-L-E-R-R-F-N-I-G-E-K-L-E-D-V-R-V-E-R-R-P-Y-Q-F-L-Y-K-E-G-E-D-Y-I-F-M-N-Q-E-T-F-D-Q-H-P-I-A-H-D-L-I-N-G-V-D-F-L-L-E-G-A-V-L-D-V-V-S-D-A-S-T-E-T-V-L-Y-A-D-M-P-I-K-V-Q-M-K-V-T-Y-T-E-P-G-M-K-G-D-T-A-T-N-T-L-K-P-A-T-V-E-S-G-A-T-V-R-V-P-L-F-I-S-E-G-E-T-I-E-I-D-T-R-D-G-S-Y-V-G-R-V-K-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-N-V-Q-V-I-N-K-S-K-H-P-L-P-A-Y-A-T-E-L-S-A-G-M-D-I-R-A-N-L-S-E-P-I-T-L-A-P-L-Q-R-C-L-V-P-T-G-I-Y-I-A-L-P-Q-G-F-E-A-Q-V-R-P-R-S-G-L-A-I-K-K-G-I-T-V-L-N-S-P-G-T-I-D-A-D-Y-R-G-E-V-C-I-I-L-V-N-L-S-S-E-P-F-V-I-E-D-G-E-R-I-A-Q-M-V-I-A-R-H-E-Q-A-V-W-Q-E-V-E-V-L-D-E-T-E-R-G-A-G-G-F-G-H-T-G-R-G"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-K-S-S-L-K-R-I-R-Q-E-E-T-R-R-L-H-N-R-Y-Y-G-K-T-M-R-N-A-V-R-K-L-R-A-T-T-D-K-K-E-A-V-A-M-Y-P-G-I-T-K-M-L-D-K-L-A-K-T-N-V-I-H-K-N-K-A-N-N-L-K-S-K-L-A-L-Y-I-N-K-L-A"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-I-E-K-K-T-V-C-Q-I-V-E-E-W-L-E-G-K-D-Y-F-L-V-E-V-T-V-S-P-D-D-K-I-V-V-E-I-D-H-A-E-G-V-W-I-E-D-C-V-E-L-S-R-F-I-E-S-K-L-N-R-E-E-E-D-Y-E-L-E-V-G-S-A-G-I-G-Q-P-F-K-V-L-Q-Q-Y-Y-I-H-I-G-Q-E-V-E-V-V-T-R-D-G-R-K-L-A-G-I-L-K-D-A-D-E-E-K-F-T-V-G-V-Q-K-K-V-K-L-E-G-S-K-R-P-K-L-I-E-E-D-E-T-F-T-Y-E-Q-I-K-Y-T-K-Y-L-I-S-F-K"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-E-I-A-S-R-V-K-A-I-I-V-D-K-L-G-V-E-E-S-E-V-T-N-E-A-S-F-T-N-D-L-G-A-D-S-L-D-T-V-E-L-I-M-E-F-E-K-E-F-G-I-S-I-P-D-D-Q-A-E-K-I-G-T-V-G-D-A-V-S-Y-I-E-E-H-A-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-V-T-Y-Q-T-E-G-V-K-M-P-D-I-K-K-R-E-T-T-E-W-I-K-N-V-A-A-S-Y-G-K-R-L-G-E-I-A-Y-I-F-C-S-D-E-K-I-L-E-V-N-R-Q-Y-L-Q-H-D-Y-Y-T-D-I-I-T-F-D-Y-C-Q-G-D-R-L-S-G-D-L-F-I-S-L-D-T-I-R-T-N-A-E-Q-F-G-A-A-Y-D-D-E-L-H-R-V-I-I-H-G-I-L-H-L-C-G-I-N-D-K-G-P-G-E-R-E-I-M-E-E-A-E-N-K-A-L-A-M-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-Y-L-D-A-A-E-K-Q-E-I-F-G-K-Y-G-K-S-N-S-D-T-G-S-T-E-A-Q-I-A-L-F-S-Y-R-I-S-H-L-T-E-H-M-K-L-N-R-K-D-Y-S-T-E-R-A-L-T-M-L-V-A-K-R-R-R-L-L-N-Y-L-K-D-K-D-I-T-R-Y-R-S-I-V-K-E-L-G-L-R-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-E-V-A-G-L-I-K-L-Q-I-K-G-G-A-A-N-P-S-P-P-V-G-P-A-L-G-S-K-G-I-N-I-M-E-F-C-K-Q-F-N-A-R-T-Q-D-K-A-G-K-I-L-P-V-I-I-T-Y-Y-A-D-K-S-F-D-F-V-I-K-T-P-P-V-A-I-Q-L-L-E-V-A-K-V-K-S-G-S-A-E-P-N-R-K-K-V-A-E-L-T-W-E-Q-I-R-T-I-A-Q-D-K-M-V-D-L-N-C-F-T-V-D-A-A-M-R-M-V-A-G-T-A-R-S-M-G-I-A-V-K-G-E-F-P-V-N-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-D-L-K-A-F-A-E-Q-L-V-N-L-T-V-K-E-V-N-E-L-A-T-I-L-K-E-E-Y-G-I-E-P-A-A-A-A-V-A-V-A-A-G-P-A-A-G-A-A-A-V-E-E-K-T-S-F-D-V-V-L-K-S-A-G-A-A-K-L-Q-V-V-K-A-V-K-E-A-C-G-L-G-L-K-E-A-K-D-M-V-D-G-A-P-S-V-V-K-E-G-L-A-K-D-E-A-E-S-L-K-K-T-L-E-E-A-G-A-E-V-E-L-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-A-K-P-K-K-R-V-I-L-P-D-P-V-F-N-D-Q-K-V-S-K-F-V-N-H-L-M-Y-D-G-K-K-N-A-S-Y-E-I-F-Y-A-A-L-E-T-V-K-A-K-L-P-N-E-E-K-S-A-L-E-I-W-K-K-A-L-D-N-V-T-P-Q-V-E-V-K-S-R-R-V-G-G-A-T-F-Q-V-P-T-E-I-R-P-D-R-K-E-S-V-S-M-K-N-L-I-L-F-A-R-K-R-G-G-K-S-M-A-D-K-L-A-A-E-I-M-D-A-F-N-E-Q-G-G-A-Y-K-R-K-E-D-M-H-R-M-A-E-A-N-R-A-F-A-H-F-R-F"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-Q-K-I-R-I-K-L-K-S-Y-D-H-N-L-V-D-K-S-A-E-K-I-V-R-T-V-K-A-T-G-A-I-V-S-G-P-I-P-L-P-T-H-K-R-I-F-T-V-N-R-S-T-F-V-N-K-K-S-R-E-Q-F-E-L-S-S-Y-K-R-L-I-D-I-Y-S-S-T-A-K-T-V-D-A-L-M-K-L-E-L-P-S-G-V-E-V-E-I-K-V"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-L-K-K-G-P-Y-I-N-V-K-L-E-K-R-I-F-A-M-N-E-S-G-K-K-V-V-V-K-T-W-A-R-A-S-M-I-S-P-D-F-V-G-H-T-V-A-V-H-N-G-N-K-F-I-P-V-Y-V-T-E-N-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-R-G-H-A-G-N-K-K-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-G-A-R-K-K-I-S-A-E-K-R-K-E-A-L-K-T-M-Y-F-A-K-L-Q-N-V-P-T-S-P-R-K-M-R-L-V-A-D-M-I-R-G-M-E-V-N-R-A-L-G-V-L-K-F-S-S-K-E-A-A-A-R-V-E-K-L-L-R-S-A-I-A-N-W-E-Q-K-N-E-R-K-A-E-S-G-E-L-F-V-T-Q-I-F-V-D-G-G-A-T-L-K-R-M-R-P-A-P-Q-G-R-G-Y-R-I-R-K-R-S-N-H-V-T-L-F-V-G-A-K-S-N-N-E-D-Q-N"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-K-T-K-F-R-R-Q-Q-K-G-R-A-K-G-N-A-Q-R-G-N-Q-L-A-F-G-S-F-G-I-K-A-L-E-T-K-W-I-T-G-R-Q-I-E-A-A-R-I-A-V-T-R-Y-M-Q-R-Q-G-Q-I-W-I-R-I-F-P-D-K-P-I-T-R-K-P-A-D-V-R-M-G-K-G-K-G-A-P-E-G-F-V-A-P-V-T-P-G-R-I-I-I-E-A-E-G-V-S-Y-E-I-A-K-E-A-L-R-L-A-A-Q-K-L-P-I-T-T-K-F-V-V-R-R-D-Y-D-I-Q-N-Q-N-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-I-S-L-M-E-A-R-N-L-R-K-E-R-T-G-V-V-L-S-N-K-M-E-K-T-I-T-V-A-A-K-F-K-E-K-H-P-I-Y-G-K-F-V-S-K-T-K-K-Y-H-A-H-D-E-K-N-E-C-N-I-G-D-T-V-R-I-M-E-T-R-P-L-S-K-T-K-R-W-R-L-V-E-I-I-E-R-A-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-V-E-S-R-L-T-V-C-D-N-S-G-A-K-E-A-L-C-I-R-V-L-G-G-T-G-R-R-Y-A-S-V-G-D-V-I-V-V-S-V-K-S-V-I-P-S-S-D-V-K-K-G-A-V-S-K-A-L-I-V-R-T-K-K-E-I-R-R-P-D-G-S-Y-I-R-F-D-D-N-A-C-V-L-L-N-N-A-G-E-I-R-G-S-R-I-F-G-P-V-A-R-E-L-R-A-T-N-M-K-V-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-K-L-H-I-K-K-G-D-T-V-Y-V-N-A-G-E-D-K-G-K-T-G-R-V-L-K-V-L-V-K-E-G-R-A-I-V-E-G-I-N-M-V-S-K-S-T-K-P-N-A-K-N-P-Q-G-G-I-V-K-Q-E-A-S-I-H-I-S-N-L-N-P-V-D-P-K-T-G-K-A-T-R-I-G-R-R-K-S-S-E-G-T-L-V-R-Y-S-K-K-S-G-E-E-I"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-N-T-A-S-L-K-K-E-Y-A-D-R-I-A-P-A-L-K-S-Q-F-Q-Y-S-S-T-M-Q-V-P-V-L-K-K-I-V-I-N-Q-G-L-G-M-A-V-A-D-K-K-I-I-E-V-A-I-N-E-M-T-A-I-T-G-Q-K-A-V-A-T-I-S-R-K-D-I-A-N-F-K-L-R-K-K-M-P-I-G-V-M-V-T-L-R-R-E-R-M-Y-E-F-L-E-K-L-V-R-V-A-L-P-R-I-R-D-F-K-G-I-E-S-K-F-D-G-K-G-N-Y-T-L-G-I-Q-E-Q-I-I-F-P-E-I-N-I-D-S-I-T-R-I-L-G-M-N-I-T-F-V-T-S-A-E-T-D-E-E-G-Y-A-L-L-K-E-F-G-L-P-F-K-N-A-K-K-D"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-E-S-M-K-A-R-E-V-K-R-A-K-L-V-A-R-Y-A-E-K-R-A-A-L-K-Q-I-V-R-T-G-E-P-A-D-A-F-E-A-A-Q-K-L-Q-E-L-P-K-N-S-N-P-I-R-M-H-N-R-C-K-L-T-G-R-P-K-G-Y-I-R-Q-F-G-I-S-R-I-Q-F-R-E-M-A-S-N-G-L-I-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-D-P-I-A-D-Y-L-T-R-L-R-N-A-I-G-A-K-H-R-V-V-E-V-P-A-S-N-L-K-K-E-I-T-K-I-L-F-E-K-G-Y-I-L-N-Y-K-F-V-E-D-G-P-Q-G-T-I-K-V-A-L-K-Y-D-S-V-N-K-V-N-A-I-K-K-L-E-R-V-S-S-P-G-M-R-K-Y-T-G-Y-K-D-M-P-R-V-I-N-G-L-G-I-A-I-I-S-T-S-K-G-V-M-T-N-K-E-A-A-E-L-K-I-G-G-E-V-L-C-Y-V-Y"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-L-P-I-S-I-P-A-G-V-T-V-T-L-K-D-D-V-V-T-V-K-G-P-K-G-E-L-S-Q-Y-V-N-P-A-I-N-V-A-I-E-D-G-H-V-T-L-T-E-N-E-K-E-M-I-D-N-P-K-Q-K-H-A-F-H-G-L-Y-R-S-L-V-H-N-M-V-V-G-V-S-E-G-Y-K-K-E-L-E-L-V-G-V-G-Y-R-A-S-N-Q-G-N-I-I-E-L-A-L-G-Y-T-H-N-I-F-I-Q-L-P-A-E-V-K-V-E-T-K-S-E-R-N-K-N-P-L-I-I-L-E-S-C-D-K-Q-L-L-G-Q-V-C-S-K-I-R-S-F-R-K-P-E-P-Y-K-G-K-G-I-K-F-V-G-E-V-I-R-R-K-S-G-K-S-A-G-A-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-T-T-K-I-E-R-R-V-K-I-K-Y-R-V-R-N-K-I-S-G-T-A-E-R-P-R-M-S-V-F-R-S-N-K-Q-I-Y-V-Q-I-I-D-D-L-S-G-K-T-L-A-A-A-S-S-L-G-M-A-E-K-V-A-K-K-E-Q-A-A-K-V-G-E-M-I-A-K-K-A-Q-E-A-G-I-T-T-V-V-F-D-R-N-G-Y-L-Y-H-G-R-V-K-E-V-A-D-A-A-R-N-G-G-L-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-G-V-N-N-R-V-K-V-T-N-D-I-E-L-K-D-R-L-V-A-I-N-R-V-T-K-V-T-K-G-G-R-T-F-S-F-S-A-I-V-V-V-G-N-E-E-G-I-I-G-W-G-L-G-K-A-G-E-V-T-A-A-I-A-K-G-V-E-S-A-K-K-N-L-V-K-V-P-V-L-K-G-T-V-P-H-E-Q-S-A-K-F-G-G-A-E-V-F-I-K-P-A-S-H-G-T-G-V-V-A-G-G-A-M-R-A-V-L-E-S-V-G-I-T-D-V-L-A-K-S-K-G-S-S-N-P-H-N-L-V-K-A-T-I-E-A-L-S-E-M-R-D-A-R-M-I-A-Q-N-R-G-I-S-V-E-K-V-F-R-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-N-L-S-N-L-K-P-A-E-G-S-T-K-T-R-K-R-I-G-R-G-A-G-S-G-L-G-G-T-S-T-R-G-H-K-G-A-K-S-R-S-G-Y-S-K-K-V-G-F-E-G-G-Q-M-P-L-Q-R-R-V-P-K-F-G-F-K-N-I-N-R-V-E-Y-K-A-I-N-L-D-T-I-Q-T-L-A-D-A-K-N-L-T-K-V-G-I-S-D-F-I-E-A-G-F-I-S-S-N-Q-L-V-K-V-L-G-N-G-A-L-T-N-K-L-E-V-E-A-N-A-F-S-K-S-A-A-A-A-I-E-A-A-G-G-T-V-V-K-L"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-Q-S-A-I-E-Q-D-G-V-I-V-E-A-L-S-N-A-M-F-R-V-E-L-E-N-G-H-E-I-T-A-H-I-S-G-K-M-R-M-H-Y-I-K-I-L-P-G-D-K-V-R-V-E-M-S-P-Y-D-L-S-K-G-R-I-V-F-R-Y-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-I-R-I-V-G-V-D-L-P-Q-N-K-R-G-E-I-A-L-T-Y-V-Y-G-I-G-R-S-S-S-A-K-I-L-D-K-A-G-V-D-K-D-L-K-V-K-D-W-T-D-D-Q-A-A-K-I-R-E-I-I-G-A-E-Y-K-V-E-G-D-L-R-S-E-I-Q-L-N-I-K-R-L-M-D-I-G-C-Y-R-G-V-R-H-R-I-G-L-P-V-R-G-Q-S-T-K-N-N-A-R-T-R-K-G-R-K-K-T-V-A-N-K-K-K-A-T-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-K-T-V-A-A-K-K-R-N-V-K-V-D-A-N-G-Q-L-H-V-H-S-S-F-N-N-I-I-V-S-L-A-N-S-E-G-Q-I-I-S-W-S-S-A-G-K-M-G-F-R-G-S-K-K-N-T-P-Y-A-A-Q-M-A-A-Q-D-C-A-K-I-A-F-D-L-G-L-R-K-V-K-A-Y-V-K-G-P-G-N-G-R-E-S-A-I-R-T-I-H-G-A-G-I-E-V-T-E-I-I-D-V-T-P-L-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-N-F-P-Q-N-L-K-Y-T-N-E-H-E-W-I-R-V-E-G-D-I-A-Y-V-G-I-T-D-Y-A-Q-E-Q-L-G-D-I-V-F-V-D-I-P-T-V-G-E-T-L-E-A-G-E-T-F-G-T-I-E-V-V-K-T-I-S-D-L-F-L-P-L-A-G-E-I-L-E-Q-N-E-A-L-E-E-N-P-E-L-V-N-K-D-P-Y-G-E-G-W-L-I-K-M-K-P-A-D-A-S-A-A-E-D-L-L-D-A-E-A-Y-K-A-V-V-N-G"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-D-L-I-K-I-A-E-E-A-F-A-T-G-K-Q-H-P-S-F-K-A-G-D-T-V-T-V-A-Y-R-I-I-E-G-N-K-E-R-V-Q-L-Y-R-G-V-V-I-K-I-A-G-H-G-D-K-K-R-F-T-V-R-K-M-S-G-T-V-G-V-E-R-I-F-P-I-E-S-P-A-I-D-S-I-E-V-N-K-V-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-T-G-K-K-A-R-I-K-E-K-R-V-N-N"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-K-T-L-F-K-S-L-K-I-T-L-V-F-C-V-F-F-S-V-F-Y-I-L-I-L-W-L-F-A-Q-V-A-G-P-N-K-G-N-A-E-V-A-T-L-D-G-K-V-V-G-A-A-N-V-G-Q-M-F-T-K-D-I-Y-F-W-G-R-P-S-C-A-G-D-G-Y-D-A-S-S-S-S-G-S-N-K-G-P-T-N-P-E-Y-L-A-E-V-E-A-R-I-D-T-F-L-V-H-H-P-Y-L-S-R-K-D-V-P-A-E-M-V-T-A-S-A-S-G-L-D-P-N-I-T-P-Q-C-A-Y-V-Q-V-K-R-V-A-Q-A-R-G-L-T-E-N-Q-V-K-E-I-V-D-Q-S-V-E-K-P-L-L-G-I-F-G-T-E-K-I-N-V-L-K-L-N-I-A-L-E-E-N-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-V-D-V-K-T-C-L-D-N-A-Q-E-K-M-D-M-A-V-M-Y-L-E-E-A-L-A-H-I-R-A-G-K-A-S-T-R-L-L-D-G-I-R-V-D-S-Y-G-S-M-V-P-I-S-N-V-A-A-L-S-T-P-D-A-R-S-I-T-I-K-P-W-D-K-S-M-F-R-A-I-E-K-A-I-I-D-S-D-L-G-I-M-P-E-N-N-G-E-V-I-R-I-G-I-P-P-L-T-E-E-R-R-R-Q-L-A-K-Q-C-K-A-E-G-E-T-A-K-V-S-V-R-N-A-R-R-D-G-I-D-A-L-K-K-A-V-K-D-G-L-A-E-D-E-Q-K-N-A-E-A-K-L-Q-K-I-H-D-K-Y-I-K-Q-I-E-D-M-L-A-D-K-D-K-E-I-M-T-V"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-N-Q-Y-E-T-V-F-I-L-T-P-V-L-S-D-V-Q-M-K-E-A-V-E-K-F-K-G-I-L-Q-A-E-G-A-E-I-I-N-E-E-N-W-G-L-K-K-L-A-Y-P-I-Q-K-K-S-T-G-F-Y-Q-L-V-E-F-N-A-D-P-T-V-I-D-K-L-E-L-N-F-R-R-D-E-R-V-I-R-F-L-T-F-K-M-D-K-Y-A-A-E-Y-A-A-K-R-R-S-V-K-S-N-K-K-E-D"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Q-Q-T-Q-S-E-I-R-Y-L-T-P-P-S-V-D-V-K-K-K-K-Y-C-R-F-K-K-S-G-I-R-Y-I-D-Y-K-D-P-E-F-L-K-K-F-L-N-E-Q-G-K-I-L-P-R-R-I-T-G-T-S-L-K-F-Q-R-R-I-A-Q-A-V-K-R-A-R-H-L-A-L-L-P-Y-V-T-D-M-M-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-I-I-L-K-E-D-I-V-N-L-G-Y-K-N-D-I-V-N-V-K-S-G-Y-G-R-N-Y-L-I-P-T-G-K-A-I-I-A-S-P-S-A-K-K-M-L-A-E-D-L-K-Q-R-A-H-K-L-E-K-I-K-K-D-A-E-A-L-A-A-K-L-E-G-V-S-L-T-I-A-T-K-V-S-S-T-G-T-I-F-G-S-V-S-N-I-Q-I-A-E-A-L-A-K-L-G-H-E-I-D-R-K-I-I-V-V-K-D-A-V-K-E-V-G-N-Y-K-A-I-V-K-L-H-K-E-V-S-V-E-I-P-F-E-V-V-A-E"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-I-K-K-E-E-V-Y-K-I-G-L-F-N-K-P-H-G-I-H-G-E-L-Q-F-T-F-T-D-D-I-F-D-R-V-D-C-D-Y-L-I-C-L-L-D-G-I-F-V-P-F-F-I-E-E-Y-R-F-R-S-D-S-T-A-L-V-K-L-E-G-I-D-T-A-E-R-A-R-M-F-T-N-V-E-V-Y-F-P-V-K-H-A-E-E-A-E-D-G-E-L-S-W-N-F-F-V-G-F-R-M-E-D-V-R-H-G-E-L-G-E-V-V-E-V-D-T-A-T-V-N-T-L-F-V-V-E-Q-E-D-G-E-E-L-L-V-P-A-Q-E-E-F-I-V-E-I-N-Q-E-K-K-L-I-T-V-E-L-P-E-G-L-L-N-L-E-D-L-E-E-D"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-T-T-L-L-V-V-G-R-T-V-E-Q-H-Y-I-T-A-I-N-D-Y-I-Q-R-T-K-R-F-I-T-F-D-M-E-V-I-P-E-L-K-N-T-K-S-L-S-M-D-Q-Q-K-E-K-E-G-E-L-I-L-K-A-L-Q-P-G-D-V-I-V-L-L-D-E-H-G-K-E-M-R-S-L-E-F-A-D-Y-M-K-R-K-M-N-T-V-N-K-R-L-V-F-V-I-G-G-P-Y-G-F-S-E-K-V-Y-Q-V-A-N-E-K-I-S-M-S-K-M-T-F-S-H-Q-M-I-R-L-I-F-V-E-Q-I-Y-R-A-M-T-I-L-N-G-G-P-Y-H-H-E"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-D-P-K-E-K-E-K-M-A-E-E-L-N-V-E-E-T-K-D-T-A-E-E-Q-P-Q-D-D-Q-A-E-E-A-A-P-L-T-H-E-E-Q-L-E-K-E-L-E-D-A-Q-A-V-I-E-E-Q-K-D-K-Y-L-R-L-S-A-E-F-D-N-Y-R-K-R-T-M-K-E-K-A-E-L-I-L-N-G-G-E-K-S-I-S-S-I-L-P-V-I-D-D-F-E-R-A-I-K-T-M-E-T-A-K-D-V-K-A-V-K-E-G-V-E-L-I-Y-N-K-F-M-A-V-M-A-Q-N-G-V-K-V-I-E-T-K-D-Q-P-L-D-T-D-Y-H-E-A-I-A-V-I-P-A-P-S-E-E-Q-K-G-K-I-L-D-C-V-Q-T-G-Y-T-L-N-D-K-V-I-R-H-A-K-V-V-V-G-E"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-S-E-N-K-Q-A-L-Q-V-A-A-L-K-N-G-T-V-I-D-H-I-P-S-E-K-L-F-T-V-V-Q-L-L-G-V-E-Q-M-K-C-N-I-T-I-G-F-N-L-D-S-K-K-L-G-K-K-G-I-I-K-I-A-D-K-F-F-C-D-E-E-I-N-R-I-S-V-V-A-P-Y-V-K-L-N-I-I-R-D-Y-E-V-V-E-K-K-E-V-R-M-P-D-E-L-H-G-I-V-K-C-A-N-P-K-C-I-T-N-N-E-P-M-P-T-L-F-H-V-I-D-K-D-N-C-I-V-K-C-H-Y-C-E-K-E-Q-K-R-E-E-I-T-I-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-E-V-G-V-L-S-M-R-Y-A-K-A-M-I-E-Y-A-Q-E-K-G-V-E-D-R-L-Y-N-E-F-F-T-L-S-H-S-F-R-V-Q-P-G-L-R-E-V-L-D-N-P-V-V-S-V-K-D-K-L-A-L-I-C-T-A-A-D-G-N-G-E-S-S-R-E-F-V-R-F-I-T-L-V-L-R-N-R-R-E-G-Y-L-Q-F-I-S-L-M-Y-L-D-L-Y-R-K-L-K-H-I-G-V-G-K-L-I-T-A-V-P-V-D-K-E-T-E-N-R-I-R-S-A-A-A-H-I-L-H-A-Q-M-E-L-D-T-V-I-D-P-S-I-E-G-G-F-I-F-D-I-N-D-Y-R-L-D-A-S-I-A-T-Q-L-K-R-V-K-Q-Q-F-I-D-K-N-R-R-I-V"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-L-L-L-P-D-S-G-L-L-F-W-M-F-V-A-F-G-V-V-F-V-I-L-A-K-Y-G-F-P-I-I-I-K-M-V-E-G-R-K-T-Y-I-D-Q-S-L-E-V-A-R-E-A-N-A-Q-L-A-H-L-K-E-E-G-E-A-L-V-A-A-A-N-K-E-Q-G-R-I-L-K-E-A-M-E-E-R-D-K-I-V-H-E-A-R-K-Q-A-E-I-A-A-Q-K-E-L-D-A-V-K-Q-Q-I-Q-I-E-K-D-E-A-I-R-D-I-R-R-Q-V-A-V-L-S-V-D-I-A-E-K-V-L-R-K-N-L-Q-D-K-E-S-Q-M-G-M-I-D-R-M-L-D-E-V-L-T-P-N-K-N"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-S-V-N-H-V-A-S-K-A-R-R-K-K-I-L-K-L-T-R-G-Y-F-G-A-R-K-N-V-W-T-V-A-K-N-T-W-E-K-G-L-T-Y-A-F-R-D-R-R-N-K-K-R-N-F-R-A-L-W-I-Q-R-I-N-A-A-A-R-L-E-G-M-S-Y-S-K-L-M-G-G-L-H-K-A-G-I-E-I-N-R-K-V-L-A-D-L-A-M-N-H-P-E-A-F-K-A-V-V-A-K-A-K-A-A"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-N-D-T-L-K-G-Q-Y-R-I-N-E-Q-I-R-A-K-E-V-R-I-V-G-D-E-I-E-P-K-V-Y-P-I-F-Q-A-L-K-M-A-E-E-K-E-L-D-L-V-E-I-S-P-N-A-Q-P-P-V-C-R-I-I-D-Y-S-K-F-L-Y-Q-L-K-K-R-Q-K-E-Q-K-A-K-Q-V-K-V-N-V-K-E-I-R-F-G-P-Q-T-D-D-H-D-Y-N-F-K-L-K-H-A-R-G-F-L-E-D-G-D-K-V-K-A-Y-V-F-F-K-G-R-S-I-L-F-K-E-Q-G-E-V-L-L-L-R-F-A-N-D-L-E-D-F-A-K-V-D-Q-M-P-V-L-E-G-K-R-M-T-I-Q-L-S-P-K-K-R-K-C-L-K-N-R-R-L-P-N-R"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-R-I-V-A-I-D-Y-G-R-K-R-T-G-I-A-V-S-D-T-L-Q-L-I-A-N-G-L-T-T-V-P-T-H-E-L-L-N-F-I-G-G-Y-V-A-K-E-P-V-E-R-I-I-I-G-L-P-K-Q-M-N-N-E-A-S-E-N-M-K-N-I-E-P-F-V-R-S-L-K-K-R-F-P-E-L-P-V-E-Y-V-D-E-R-F-T-S-V-L-A-H-R-T-M-L-E-A-G-L-K-K-K-D-R-Q-N-K-A-L-V-D-E-I-S-A-T-I-I-L-Q-T-Y-L-E-S-K-R-F"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-Q-P-S-V-N-I-K-N-K-R-A-T-F-D-Y-E-L-M-D-T-Y-T-A-G-I-V-L-T-G-T-E-I-K-S-I-R-L-G-K-A-S-L-V-D-T-F-C-Y-F-A-K-G-E-L-W-V-K-N-M-H-I-A-E-Y-F-Y-G-S-Y-N-N-H-T-A-R-R-D-R-K-L-L-L-N-K-K-E-L-E-K-I-Q-R-G-M-K-D-P-G-F-T-T-V-P-V-R-L-F-I-N-E-K-G-L-A-K-L-V-V-A-L-A-K-G-K-K-Q-Y-D-K-R-E-S-I-K-E-K-D-D-R-R-D-M-A-R-M-F-K-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-V-P-C-R-L-R-P-F-L-W-N-S-P-K-V-A-V-K-R-I-P-R-Q-C-I-E-G-I-V-V-S-T-K-M-Q-K-T-V-V-I-E-V-E-R-T-K-K-H-P-K-Y-G-K-T-V-Q-Y-T-K-K-Y-K-I-H-D-P-L-E-E-C-S-V-G-D-R-V-L-A-H-E-T-R-H-F-S-K-T-K-Y-F-R-F-Y-R-K-L-Y"} +{"text": "### FUNCTION Escorts unspliced or incompletely spliced viral pre-mRNAs ### SEQUENCE -M-A-G-R-E-E-D-A-N-L-L-Y-T-V-R-I-I-K-I-L-Y-D-S-N-P-Y-P-S-G-A-G-S-R-T-A-R-R-N-R-R-R-R-W-R-Q-R-Q-H-Q-V-D-A-L-A-S-R-I-L-Q-Y-R-L-G-G-P-Q-E-P-P-H-L-D-I-P-D-L-S-K-L-H-L-D-P-L-D-Q-P-A-S-T-E-T-G-D-N-Q-L-G-T-Q-P-S-N-S-A"} +{"text": "### FUNCTION Nuclear transcriptional activator of viral gene expression, that is essential for viral transcription from the LTR promoter and replication Acts as a sequence-specific molecular adapter, directing components of the cellular transcription machinery to the viral RNA to promote processive transcription elongation by the RNA polymerase II ### SEQUENCE -M-N-P-I-D-P-Q-V-A-P-W-E-H-P-G-A-A-P-E-T-P-C-T-N-C-Y-C-K-K-C-C-F-H-C-P-V-C-F-T-K-K-A-L-G-I-S-Y-G-R-K-R-R-G-R-K-S-A-V-H-S-T-N-N-Q-D-P-V-R-Q-Q-S-L-P-K-R-S-R-I-Q-N-S-Q-E-E-S-Q-E-E-V-E-A-E-T-T-S-G-G-R-P-R-Q-Q-D-S-S-V-S-S-G-R-T-S-G-T-S-S-S-G-Y-T-R-P-F-K-T-S-S-G-S-S-G-S-A-C-K-H"} +{"text": "### FUNCTION Stimulates gene expression driven by the HIV-2 LTR Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle Cell cycle arrest creates a favorable environment for maximizing viral expression and production ### SEQUENCE -M-E-Q-A-P-N-D-N-G-P-Q-R-E-P-Y-T-E-W-L-L-D-I-L-E-E-I-K-Q-E-A-V-K-H-F-P-R-P-I-L-Q-G-V-G-N-W-V-F-T-I-Y-G-D-S-W-E-G-V-Q-E-L-I-K-I-L-Q-R-A-L-F-T-H-Y-R-H-G-C-I-H-S-R-I-G-S"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-D-G-F-G-S-D-F-S-V-G-G-S-S-S-G-K-V-D-T-G-A-I-M-E-Q-V-K-V-Q-I-A-V-A-N-A-Q-E-L-L-Q-R-M-T-D-K-C-F-R-K-C-I-G-K-P-G-G-S-L-D-N-S-E-Q-K-C-V-A-M-C-M-D-R-Y-M-D-A-W-N-I-V-S-R-A-Y-N-S-R-L-Q-R-E-R-A-K-M"} +{"text": "### FUNCTION Probable regulator of exocrine pancreas development ### SEQUENCE -M-A-A-I-P-S-S-G-S-L-V-A-T-H-D-Y-Y-R-R-R-L-G-S-T-S-S-S-S-S-C-G-S-V-D-Y-S-G-E-V-I-P-H-H-P-G-L-P-K-A-D-P-G-H-W-W-A-S-F-F-F-G-K-S-T-H-P-V-M-T-T-V-S-E-S-P-E-N-S-G-S-F-R-I-T-N-G-L-V-P-C-G-L-T-Q-E-S-V-Q-K-Q-K-V-S-D-S-K-S-N-S-S-P-S-A"} +{"text": "### FUNCTION Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability Required for efficient homologous recombination-dependent repair of double-strand breaks ### SEQUENCE -M-D-P-G-S-T-A-S-P-L-Q-C-T-A-G-F-P-S-K-N-R-V-A-I-L-A-E-L-D-K-E-K-R-K-L-L-L-Q-N-Q-S-S-T-N-N-P-G-A-S-I-A-L-A-R-P-N-M-N-K-D-F-R-D-H-S-E-Q-Q-H-I-A-A-Q-Q-K-A-A-L-Q-H-A-H-A-H-S-S-G-Y-F-I-T-Q-D-S-A-F-G-N-L-I-L-P-V-I-P-R-L-E-A-E"} +{"text": "### FUNCTION Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the tom40 translocation pore ### SEQUENCE -M-V-A-V-G-K-T-S-A-I-A-A-G-V-C-G-A-L-L-L-G-Y-C-I-Y-F-D-R-K-R-R-S-D-P-N-F-K-N-R-L-R-E-K-R-R-K-Q-K-I-A-K-E-R-A-G-Q-S-R-L-P-D-L-K-D-A-E-A-V-Q-K-F-F-L-E-E-I-Q-L-G-E-E-L-L-A-Q-G-D-F-E-K-G-V-D-H-L-T-N-A-I-A-I-C-G-Q-P-Q-Q-L-L-Q-V-L-Q-Q-T-L-P-P-P-V-F-Q-M-L-L-T-K-L-P-T-I-S-Q-R-I-G-N-A-Q-N-L-S-E-D-D-V-E"} +{"text": "### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-D-C-A-K-T-G-A-C-N-C-G-A-T-C-K-C-T-N-C-Q-C-K-T-C-K-K-S-C-C-P-C-C-P-S-G-C-S-K-C-A-S-G-C-V-C-K-D-N-S-C-G-S-S-C-C-Q"} +{"text": "### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-D-C-A-K-T-G-P-C-N-C-G-A-T-C-K-C-T-N-C-Q-C-T-T-C-K-K-S-C-C-S-C-C-P-S-G-C-S-K-C-A-S-G-C-V-C-K-G-N-S-C-G-S-S-C-C-Q"} +{"text": "### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-R-A-L-I-L-L-S-L-G-L-L-R-V-A-V-P-S-P-P-Q-V-V-V-Y-T-Y-K-P-V-V-H-G-E-K-N-T-L-L-C-H-A-K-E-F-N-P-P-N-V-E-L-Q-L-F-E-D-G-N-V-F-S-Q-A-N-Q-T-D-L-S-F-E-S-N-W-K-F-K-L-T-K-F-I-E-L-I-P-R-E-D-V-E-Y-S-C-H-V-M-Y-M-G-K-T-S-I-Y-K-L-E-S-F"} +{"text": "### FUNCTION Beta-bungarotoxin is a presynaptic neurotoxin of the venom The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and is non-toxic ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-W-A-E-L-T-P-V-S-S-R-K-R-H-P-D-C-D-K-P-P-D-T-R-I-C-Q-T-V-V-R-A-F-Y-Y-K-P-S-E-K-R-C-V-Q-F-R-Y-G-G-C-K-G-N-G-N-H-F-K-S-D-H-L-C-R-C-E-C-L-E-Y-R"} +{"text": "### FUNCTION Beta-bungarotoxin is a presynaptic neurotoxin of the venom The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and is non-toxic ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-W-A-E-L-T-P-V-S-S-R-K-R-H-P-D-C-D-K-P-P-D-T-K-I-C-Q-T-V-V-R-A-F-Y-Y-K-P-S-A-K-R-C-V-Q-F-R-Y-G-G-C-N-G-N-G-N-H-F-K-S-D-H-L-C-R-C-E-C-L-E-Y-P"} +{"text": "### FUNCTION Beta-bungarotoxin is a presynaptic neurotoxin of the venom The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and is non-toxic ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-C-A-E-L-T-P-V-S-S-R-Q-R-H-R-D-C-D-K-P-P-D-K-G-N-C-G-S-V-R-R-A-F-Y-Y-D-T-R-L-K-T-C-K-A-F-P-Y-R-G-C-N-G-N-G-N-H-F-K-T-E-T-L-C-R-C-E-C-L-V-Y-P"} +{"text": "### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-T-C-L-I-C-P-E-K-D-C-Q-K-V-H-T-C-R-N-E-E-K-I-C-V-K-R-F-Y-D-K-N-Q-L-G-W-R-A-Q-R-G-C-A-V-S-C-P-K-A-K-P-N-E-T-V-Q-C-C-S-T-D-D-C-N-R"} +{"text": "### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-A-I-V-C-L-D-L-G-Y-T-L-T-C-L-I-C-P-E-K-D-C-Q-K-V-H-T-C-R-N-E-E-K-I-C-V-K-R-S-Y-D-K-N-Q-L-G-W-R-A-Q-R-G-C-A-V-S-C-P-K-A-K-P-N-E-T-V-Q-C-C-S-T-D-K-C-N-K"} +{"text": "### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-A-I-V-C-L-D-L-G-Y-T-L-T-C-L-I-C-P-E-K-D-C-Q-K-V-H-T-C-R-N-E-E-K-I-C-V-K-R-F-Y-D-K-N-Q-L-G-W-R-A-Q-R-G-C-A-V-S-C-P-K-A-K-P-N-E-T-V-Q-C-C-S-T-D-K-C-N-K"} +{"text": "### FUNCTION Postsynaptic neurotoxin that binds and inhibits neuronal nicotinic acetylcholine receptors Is a selective, and slowly reversible antagonist of alpha-3/CHRNA3-containing and some alpha-4/CHRNA4-containing AChRs ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-T-C-L-I-S-P-S-S-T-P-Q-T-C-P-Q-G-Q-G-I-C-F-L-K-A-Q-C-D-K-F-C-S-I-R-G-P-V-I-E-Q-G-C-V-A-T-C-P-Q-F-R-S-N-Y-R-S-L-L-C-C-T-T-D-N-C-N-H"} +{"text": "### FUNCTION Postsynaptic neurotoxin that binds and inhibits neuronal nicotinic acetylcholine receptors Is a selective, and slowly reversible antagonist of alpha-3/CHRNA3-containing and some alpha-4/CHRNA4-containing AChRs ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-T-C-L-I-S-P-S-S-T-P-Q-T-C-P-Q-G-Q-D-I-C-F-L-K-A-Q-C-D-K-F-C-S-I-R-G-P-V-I-E-Q-G-C-V-A-T-C-P-Q-F-R-S-N-Y-R-S-L-L-C-C-T-T-D-N-C-N-H"} +{"text": "### FUNCTION May be involved in the cellular control mechanism of the secretion of toxins from the gland into the venom ### SEQUENCE -M-A-A-T-L-T-P-E-Q-I-T-E-Y-K-G-I-F-E-M-F-D-E-E-G-N-G-L-V-K-T-D-D-L-E-S-L-M-S-L-V-G-I-N-P-T-K-R-D-L-A-N-M-A-K-D-V-D-K-D-K-K-G-T-F-N-C-D-G-F-L-A-L-M-G-I-Y-H-E-K-S-K-N-Q-D-E-E-L-R-A-A-F-K-V-F-D-K-E-H-K-G-Y-I-E-W-D-T-L-K-Y-V-L-M-N-A-G-E-P-L-N-E-Q-E-A-E-L-M-M-K-E-A-D-K-D-G-D-G-T-I-D-Y-E-E-F-V-A-M-M-T-G-E-S-F-K-L-T-Q"} +{"text": "### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-G-L-L-I-C-S-L-L-L-G-L-L-C-C-S-M-A-K-D-T-P-P-K-V-E-V-Y-T-R-E-P-E-E-F-G-K-P-N-S-F-I-C-H-V-S-G-F-Y-P-P-Q-I-N-I-T-L-L-K-D-G-K-E-I-P-N-T-Q-Q-T-D-L-A-F-E-A-N-W-Y-Y-Y-L-T-K-H-V-S-F-T-P-K-E-D-D-E-F-I-C-R-V-T-H-M-G-K-S-K-D-H-F-L-M-I-G-L"} +{"text": "### FUNCTION May play a role in the regulation of cellular reactive oxygen species metabolism May participate in cell growth regulation ### SEQUENCE -M-S-T-N-N-C-T-F-K-D-R-C-V-S-I-L-C-C-K-F-C-K-Q-V-L-S-S-R-G-M-K-A-V-L-L-A-D-T-D-I-D-L-F-S-T-D-I-P-P-T-N-T-V-D-F-I-G-R-C-Y-F-T-G-I-C-K-C-K-L-K-D-I-A-C-L-K-C-G-N-I-V-G-Y-H-V-I-V-P-C-S-S-C-L-L-S-C-N-N-G-H-F-W-M-F-H-S-Q-A-V-Y-G-I-N-R-L-D-A-T-G-V-N-L-L-L-W-G-N-L-P-E-T-E-E-C-T-D-E-E-T-L-E-I-S-A-E-E-Y-I-R"} +{"text": "### FUNCTION May modulate activity of cullin-RING E3 ubiquitin ligase complexes Associates with the NF-kappa-B complex and suppresses its transcriptional activity ### SEQUENCE -M-G-R-L-H-C-T-Q-D-P-V-P-E-A-V-R-G-D-M-Q-Q-L-N-Q-L-G-A-Q-Q-F-S-D-L-T-E-V-L-F-H-F-L-T-E-P-K-E-V-E-R-F-L-A-Q-L-S-E-F-A-T-S-N-Q-I-S-L-G-P-L-K-S-I-M-K-S-L-L-L-V-P-N-G-A-L-K-K-G-L-T-A-E-Q-V-R-T-D-L-Q-T-L-G-L-S-E-E-K-A-T-Y-F-S-E-K-W-K-Q-N-A-S-T-L-A-Q-W-A-M-G-Q-T-L-M-V-N-Q-L-I-D-M-E-W-R-F-G-V-T-S-G-S-S-E-L-E-K-V-G-S-I-F-L-Q-L-K-L-V-V-K-K-G-K-Q-T-E-N-L-Y-M-E-L-T-L-P-Q-F-Y-S-F-L-H-E-M-E-R-V-R-A-S-M-E-C-L-S"} +{"text": "### FUNCTION May play a role in ciliary assembly ### SEQUENCE -M-A-S-L-F-T-Q-E-I-H-L-S-K-R-H-E-E-I-L-S-Q-R-L-M-L-L-Q-K-M-K-N-K-F-G-D-E-N-T-E-R-A-S-L-L-Q-A-T-E-T-A-S-R-R-N-L-R-L-L-K-D-I-D-A-A-E-E-A-F-Q-T-K-L-I-P-H-P-Q-P-S-M-L-S-L-E-T-R-Y-W-A-S-V-E-E-H-I-P-K-W-E-L-F-L-L-G-R-A-P-Y-P-I-G-A-E-N-Q-N-E-V-P-F-V-Q-T-E-A-K-L"} +{"text": "### FUNCTION May play a role in TRPCs intracellular trafficking ### SEQUENCE -M-S-S-D-F-P-H-Y-N-F-R-M-P-N-I-G-F-Q-N-L-P-L-N-I-Y-I-V-V-F-G-T-A-V-F-V-F-I-L-S-L-L-F-C-C-Y-L-I-R-L-R-H-Q-A-H-K-E-F-Y-A-Y-K-Q-V-I-L-K-E-K-V-K-E-L-N-L-H-E-L-C-A-V-C-L-E-D-F-K-P-R-D-E-L-G-I-C-P-C-K-H-A-F-H-R-K-C-L-V-K-W-L-E-V-R-K-V-C-P-L-C-N-M-P-V-L-Q-L-A-Q-L-H-S-K-Q-D-R-G-P-P-Q-E-P-L-P-G-A-E-N-I-V"} +{"text": "### FUNCTION Regulates drug efflux through modulation of ABCB1 localization and activity ### SEQUENCE -M-T-V-G-A-R-L-R-S-K-A-A-S-S-L-V-G-R-R-P-L-G-R-S-R-R-A-G-D-E-E-T-D-A-I-V-E-H-L-E-G-E-D-E-D-P-A-S-P-D-C-E-R-E-E-G-G-R-R-A-G-T-P-S-A-R-R-V-H-L-A-A-L-P-E-R-Y-D-S-L-E-E-P-A-P-G-D-K-P-K-K-R-Y-R-R-K-L-K-K-Y-G-K-N-F-G-K-A-I-S-K-G-C-R-Y-I-V-I-G-L-Q-G-F-A-A-A-Y-S-A-P-F-G-V-A-T-S-V-V-S-F-V-R"} +{"text": "### FUNCTION Has antibacterial activity ### SEQUENCE -M-P-V-T-K-S-Y-F-M-T-V-V-V-V-L-I-L-V-D-E-T-T-G-G-L-F-G-F-R-S-S-K-R-Q-E-P-W-I-A-C-E-L-Y-Q-G-L-C-R-N-A-C-Q-K-Y-E-I-Q-Y-L-S-C-P-K-T-R-K-C-C-L-K-Y-P-R-K-I-T-S-F"} +{"text": "### FUNCTION Core component of the MITRAC complex, that regulates cytochrome c oxidase assembly Requires for coordination of the early steps of cytochrome c oxidase assembly with the synthesis of MT-CO1 ### SEQUENCE -M-P-S-A-K-Q-L-A-D-I-G-Y-K-T-F-S-A-S-M-M-L-L-T-V-Y-G-G-Y-L-C-S-V-R-A-Y-R-Y-L-Q-L-R-S-A-R-R-Q-A-A-E-E-Q-K-T-S-G-V-L"} +{"text": "### FUNCTION Antibacterial protein ### SEQUENCE -M-K-P-S-S-L-L-L-F-T-T-T-I-L-L-C-L-S-M-A-Q-P-R-A-T-R-K-G-V-T-P-K-Q-G-Y-C-P-E-F-L-L-D-C-P-F-V-L-L-P-V-C-S-R-D-K-G-C-K-G-T-K-K-C-C-F-Y-Y-C-Q-M-R-C-V-E-P-W-T-T-L-T"} +{"text": "### FUNCTION Plays a role in mitochondrial morphogenesis ### SEQUENCE -M-A-A-W-G-R-R-R-L-G-P-G-G-G-G-S-R-E-R-V-S-L-S-A-T-D-C-Y-I-V-H-E-I-Y-S-G-E-N-A-Q-D-Q-F-E-Y-E-L-E-Q-A-L-E-A-Q-Y-K-Y-I-V-I-E-P-T-R-I-G-D-E-T-A-R-W-I-T-V-G-N-C-L-H-K-T-A-V-L-A-G-T-A-C-L-F-T-P-L-A-L-P-L-D-Y-S-H-Y-I-S-L-P-A-G-V-L-S-L-A-C-C-T-L-Y-G-I-S-W-Q-F-D-P-C-C-K-Y-Q-V-E-Y-D-A-Y-K-L-S-R-L-P-L-H-T-L-T-S-S-T-P-V-V-L-V-R-K-D-D-L-H-R-K-R-L-H-N-T-I-A-L-A-A-L-V-Y-C-V-K-K-V-Y-E-L-Y-A-V"} +{"text": "### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase to ubiquinol Promotes maturation of the iron-sulfur protein subunit Sdhb of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants May act together with SDHAF1 ### SEQUENCE -M-P-G-K-H-V-S-R-V-R-A-L-Y-R-R-I-L-L-L-H-R-A-L-P-P-D-L-K-A-L-G-D-Q-Y-V-K-D-E-F-R-R-H-K-T-V-G-P-G-E-A-Q-R-F-L-K-E-W-E-T-Y-A-A-V-L-W-Q-Q-A-E-D-S-R-Q-S-S-T-G-K-A-C-F-G-T-S-L-P-E-E-K-L-N-D-F-R-D-E-Q-I-G-Q-L-Q-E-L-M-Q-E-A-T-K-P-N-R-Q-F-S-I-T-E-S-T-K-P-Q-L"} +{"text": "### FUNCTION Putative COX assembly factor ### SEQUENCE -M-S-T-S-V-P-Q-G-H-N-W-T-R-P-V-K-K-D-D-D-E-E-D-P-L-D-Q-L-I-T-R-S-G-C-A-A-S-H-F-A-V-Q-E-C-M-A-Q-H-Q-D-W-R-Q-C-Q-P-Q-V-Q-A-F-R-D-C-M-S-A-Q-Q-A-R-R-R-E-E-L-Q-R-R-K-E-Q-A-S-A-Q-H"} +{"text": "### FUNCTION May play a role in BANF1 regulation and influence tissue-specific roles of BANF1 ### SEQUENCE -M-D-D-M-S-P-R-L-R-A-F-L-S-E-P-I-G-E-K-D-V-A-W-V-D-G-I-S-R-E-L-A-I-N-L-V-T-K-G-F-N-K-A-Y-V-L-L-G-Q-F-L-L-M-H-K-N-E-A-E-F-Q-R-W-I-I-C-C-C-G-A-T-E-C-E-A-R-Q-S-S-T-C-L-K-E-W-C-S-C-F-L"} +{"text": "### FUNCTION May modulate activity of cullin-RING E3 ubiquitin ligase complexes May down-regulate activation of NF-kappa-B ### SEQUENCE -M-L-L-D-L-S-E-E-H-K-E-H-L-A-F-L-P-Q-V-D-T-A-V-V-A-E-F-G-R-I-A-V-E-F-L-R-R-G-S-N-P-K-I-Y-E-G-A-A-R-K-L-N-V-S-S-D-T-I-Q-H-G-V-E-G-L-T-Y-L-L-T-E-S-S-K-L-M-I-S-E-L-D-F-Q-D-S-V-F-V-L-G-F-S-E-E-L-N-K-L-L-L-Q-L-Y-L-D-N-R-K-E-I-R-T-I-L-N-E-L-A-P-R-L-P-S-Y-H-S-L-E-W-R-L-D-V-Q-L-A-S-R-S-L-R-Q-Q-I-K-P-A-V-T-I-K-L-H-L-D-Q-N-G-D-H-S-T-H-F-L-Q-T-D-P-A-T-L-L-H-L-V-Q-Q-L-E-Q-A-L-E-E-M-K-T-N-H-C-R-R-V-V-R-S-I-K"} +{"text": "### FUNCTION May be involved in 20S pre-rRNA processing ### SEQUENCE -M-A-G-A-A-E-D-V-R-V-L-F-G-A-A-V-R-A-A-L-E-A-W-P-A-L-Q-I-A-V-E-N-G-F-G-G-V-H-S-Q-E-K-A-E-W-L-G-G-A-V-E-D-Y-F-I-A-N-A-D-L-E-L-E-E-I-E-D-F-L-G-E-L-M-T-T-E-F-D-T-V-V-E-D-G-S-L-P-Q-V-S-Q-Q-L-Q-T-M-F-H-H-F-Q-K-G-D-G-A-A-L-Q-E-M-T-S-Q-I-N-Q-K-K-C-K-V-T-A-T-P-L-M-T-A-K-E-T-D-V-A-E-D-D-V-D-S-V-E-E-M-E-V-T-A-T-N-D-G-A-T-T-D-E-V-C-P-Q-P-Q-P-S-D-P-D-T-Q-T-I-K-E-E-D-I-V-E-D-G-W-T-I-V-R-R-K-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in rRNA maturation ### SEQUENCE -M-S-L-V-I-K-N-L-Q-R-V-V-P-I-R-R-V-P-L-R-R-K-M-D-L-V-R-S-I-L-G-V-K-K-F-D-L-G-I-I-C-V-D-N-K-T-I-Q-N-I-N-R-I-Y-R-N-K-N-V-P-T-D-V-L-S-F-S-F-H-E-N-L-K-A-G-E-F-P-Q-P-H-S-P-D-D-Y-N-L-G-D-I-F-L-G-V-E-Y-I-L-Q-H-C-R-E-S-E-D-Y-C-D-V-L-T-V-T-A-T-H-G-L-C-H-L-L-G-F-T-H-S-S-K-A-E-W-Q-K-M-Y-N-Q-E-K-L-V-L-E-E-L-S-R-Y-T-G-A-R-L-Q-P-L-S-R-G-L-Y"} +{"text": "### FUNCTION May be involved in transcriptional regulation ### SEQUENCE -M-E-K-F-Y-K-E-N-E-G-K-P-E-N-K-G-R-A-E-D-E-G-S-T-E-E-G-G-K-A-D-E-D-K-S-D-A-E-G-K-P-A-R-Q-G-K-L-E-V-E-G-G-P-G-E-Q-A-Q-Q-K-G-E-G-K-P-E-K-Q-G-K-S-D-G-E-G-K-R-Q-G-E-S-K-P-D-S-Q-A-K-S-A-S-E-A-R-A-A-E-K-R-P-A-E-D-Y-V-P-R-K-A-K-R-K-T-D-R-G-T-D-D-S-P-K-N-S-Q-E-D-L-Q-D-R-H-V-S-S-E-E-M-M-R-E-C-A-D-M-T-R-A-Q-E-E-L-R-K-R-Q-K-M-G-G-F-H-W-V-P-R-D-A-Q-D-A-L-V-P-R-G-Q-R-G-V-R-G-V-R-G-G-G-G-R-G-Q-K-D-L-E-D-A-P-F-V"} +{"text": "### FUNCTION Acts as a mitochondrial iron-sulfur cluster insertion into a subset of mitochondrial proteins Probably acts together with NFU1 ### SEQUENCE -M-A-A-W-G-P-A-A-A-A-P-L-L-R-G-S-R-G-L-P-L-W-H-C-A-Q-R-M-F-A-S-Q-T-E-G-E-L-K-V-T-Q-V-L-K-E-K-F-P-R-A-T-A-I-Q-V-T-D-I-S-G-G-C-G-A-M-Y-E-I-K-I-E-S-E-E-F-K-E-K-R-T-V-Q-Q-H-Q-M-V-N-Q-A-L-K-E-E-I-K-G-M-H-G-L-R-I-F-T-S-V-P-K-C"} +{"text": "### FUNCTION Cross-linked envelope protein of keratinocytes Involved in UV-induced cornification ### SEQUENCE -M-P-S-H-Q-H-Q-N-Q-Q-Q-C-T-P-Q-A-Q-Q-Q-Q-V-K-Q-P-C-Q-P-P-P-T-K-C-Q-E-A-C-V-P-K-T-K-D-P-C-V-P-Q-A-K-K-Q-C-P-A-R-S-T-T-N-P-A-Q-E-K-C-P-A-Q-Q-D-P-K-C-K-Q-K"} +{"text": "### FUNCTION Important role in the capacity of milk to transport calcium phosphate ### SEQUENCE -M-K-F-I-I-L-T-C-L-L-A-V-A-L-A-K-Q-E-S-K-D-N-S-Q-E-D-F-K-Q-T-V-D-V-V-I-F-P-G-Q-E-T-V-K-N-I-P-I-P-Q-M-E-S-V-E-A-P-I-K-N-K-C-Y-Q-S-I-Q-T-F-K-P-P-Q-A-L-K-G-L-Y-Q-Y-H-M-A-K-N-P-W-G-Y-T-V-N-R-A-F-P-S-T-R-T-L-Q-Y-N-Q-K-T-M-D-L-S-M-R-A-R-E-K-I-V-M-S-E-I-K-K-N-I-Q-D-Y-V-T-K-M-K-Q-Y-S-K-I-T-W-P-R-F-V-K-S-L-Q-Q-Y-Q-K-T-M-N-P-W-S-C-Y-P-Y-T-L-L-Q-V"} +{"text": "### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-A-R-T-V-A-T-F-F-L-M-L-V-S-L-A-C-L-D-A-I-E-R-P-P-Q-V-Q-V-Y-T-R-H-P-P-E-N-G-K-T-N-F-L-N-C-Y-V-S-Q-F-H-P-P-H-I-E-I-E-L-L-K-N-G-K-K-I-E-K-V-E-M-S-D-L-S-F-S-K-D-W-T-F-Y-L-L-A-H-T-E-F-T-P-T-A-N-D-K-Y-A-C-R-V-S-H-V-T-L-K-E-P-K-V-V-T-W-E-R-D-M"} +{"text": "### FUNCTION This protein is involved in control of the biosynthesis of threonine ### SEQUENCE -M-R-Y-I-S-L-N-T-T-I-I-T-T-T-E-T-T-G-Y-G-A-G"} +{"text": "### FUNCTION May be involved in the biosynthesis of molybdopterin ### SEQUENCE -M-H-K-H-Q-H-Q-N-I-H-L-N-R-P-I-H-V-A-I-L-T-V-S-D-T-R-D-Y-D-S-D-K-G-G-Q-L-I-Q-S-L-I-N-Q-H-E-N-H-V-D-I-N-H-Y-R-I-V-K-D-D-I-E-A-I-T-H-Q-L-K-L-W-L-T-S-S-N-Q-L-D-V-I-I-T-T-G-G-T-G-I-S-Q-R-D-V-T-I-E-A-V-R-P-L-L-T-K-E-L-E-G-F-G-E-L-F-R-Y-L-S-Y-T-E-D-V-G-T-R-A-L-L-T-R-A-I-A-G-T-C-D-S-T-L-I-F-A-L-P-G-S-T-G-A-I-K-L-A-I-E-K-L-I-K-P-E-L-S-H-L-V-F-E-L-N-K-D-I-R-N"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-I-P-D-K-N-A-T-S-D-N-E-E-S-D-E-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-E-K-A-Y-R-I-K-R-N-S-D-F-Q-A-I-Y-K-N-G-K-S-V-A-N-R-Q-F-V-V-Y-T-Y-K-N-R-D-L-K-H-F-R-L-G-I-S-V-S-K-K-L-G-N-A-V-T-R-N-R-I-K-R-A-I-R-E-N-F-K-V-H-K-Q-N-I-I-A-K-D-I-I-V-I-A-R-Q-P-A-K-D-M-N-T-L-E-I-Q-S-S-L-E-H-V-L-K-I-A-K-V-F-N-K-K-I-K"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-S-K-L-I-D-S-F-M-K-L-P-G-I-G-P-K-T-A-Q-R-L-A-F-H-T-L-D-M-K-E-D-D-V-V-K-F-A-K-A-L-V-D-V-K-R-E-L-T-Y-C-S-V-C-G-H-I-T-E-N-D-P-C-Y-I-C-E-D-K-Q-R-D-R-S-V-I-C-V-V-E-D-D-K-D-V-I-A-M-E-K-M-R-E-Y-K-G-L-Y-H-V-L-H-G-S-I-S-P-M-D-G-I-G-P-E-D-I-N-I-P-A-L-V-E-R-L-K-N-D-E-V-K-E-L-I-L-A-M-N-P-N-L-E-G-E-S-T-A-M-Y-I-S-R-L-V-K-P-I-G-I-K-V-T-R-L-A-Q-G-L-S-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-I-A-G-R-T-E-M"} +{"text": "### FUNCTION Chaperone that serves for the intracellular sequestration and transport of Cu ### SEQUENCE -M-T-Q-K-I-I-K-V-E-G-M-S-C-E-H-C-R-N-A-V-E-S-A-L-A-K-L-N-G-V-S-S-A-E-V-N-L-D-E-N-H-V-R-V-E-Y-N-D-S-K-V-T-F-E-N-M-K-E-A-I-E-E-Q-G-Y-D-V-K"} +{"text": "### FUNCTION Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB The LrgAB and CidAB proteins may affect the proton motive force of the membrane May be involved in programmed cell death , possibly triggering PCD in response to antibiotics and environmental stresses ### SEQUENCE -M-V-I-L-E-Q-T-H-L-V-K-N-K-A-V-D-N-K-K-S-M-K-Y-S-I-F-Q-Q-A-L-T-I-A-V-I-L-L-I-S-K-I-I-E-S-F-M-P-I-P-M-P-A-S-V-I-G-L-V-L-L-F-I-A-L-C-T-G-I-V-K-L-G-Q-V-E-T-V-G-T-A-L-T-N-N-I-G-F-L-F-V-P-A-G-I-S-V-I-N-S-L-P-I-L-K-Q-S-P-I-L-I-I-L-L-I-I-I-S-T-L-L-L-L-I-C-T-G-F-S-S-Q-L-L-V-T-K-S-L-F-P-S-K-E-K-N-E-E-T-S-H-I-G-G"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-I-E-E-I-Q-G-N-I-A-N-L-S-Q-D-E-K-Q-K-H-V-E-K-V-Y-L-E-N-S-D-L-V-K-R-I-Q-R-V-K-T-D-H-G-N-E-I-G-I-R-L-K-Q-P-I-D-L-Q-Y-G-D-I-L-Y-Q-D-D-T-N-M-I-I-V-D-V-N-S-E-D-L-L-V-I-K-P-R-N-L-K-E-M-G-D-I-A-H-Q-L-G-N-R-H-L-P-A-Q-F-T-E-T-E-M-L-I-Q-Y-D-Y-L-V-E-D-L-L-K-E-L-G-I-P-Y-S-H-E-D-R-K-V-N-Q-A-F-R-H-I-G-H-S-H-D"} +{"text": "### FUNCTION May play a key role in alkaline pH tolerance ### SEQUENCE -M-A-V-D-N-N-K-A-K-Q-A-Y-D-N-Q-T-G-V-N-E-Q-E-R-K-E-Q-Q-Q-A-Q-N-N-Q-P-Q-F-E-N-K-L-T-F-S-D-E-V-V-E-K-I-A-G-I-A-A-R-E-V-K-G-I-L-D-M-K-G-G-F-T-D-S-F-T-N-A-F-S-N-G-N-N-V-T-T-G-V-S-V-E-V-G-E-K-Q-A-A-V-D-L-K-V-I-L-E-Y-G-E-S-A-P-K-I-F-R-K-V-T-D-L-V-K-E-Q-V-K-Y-I-T-G-L-E-V-V-E-V-N-M-Q-V-D-D-V-M-T-K-K-E-W-Q-Q-K-N-E-K-D-N-K-E-N-N-E-R-E-G-L-K"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-T-K-M-N-V-E-S-F-N-L-D-H-T-K-V-V-A-P-F-I-R-L-A-G-T-M-E-G-L-N-G-D-V-I-H-K-Y-D-I-R-F-K-Q-P-N-K-E-H-M-D-M-P-G-L-H-S-L-E-H-L-M-A-E-N-I-R-N-H-T-D-K-V-V-D-L-S-P-M-G-C-Q-T-G-F-Y-V-S-F-I-N-H-D-D-Y-D-D-V-L-N-I-I-D-Q-T-L-H-D-V-L-N-A-S-E-V-P-A-C-N-E-V-Q-C-G-W-A-A-S-H-S-L-E-G-A-K-T-I-A-Q-A-F-L-D-K-R-E-Q-W-N-D-I-Y-G-E-G-K"} +{"text": "### FUNCTION Dephosphorylates the phosphotyrosine-containing proteins ### SEQUENCE -M-K-I-I-F-V-C-S-G-N-T-C-R-S-P-L-A-E-S-I-A-K-S-L-L-P-H-D-S-I-A-S-R-G-L-F-A-V-E-G-Q-A-I-S-K-E-S-L-E-L-I-H-K-Y-D-L-P-E-P-S-R-A-Q-A-F-H-I-D-D-L-D-A-D-I-I-L-T-M-T-Q-A-H-K-D-L-I-F-S-M-Y-G-R-Q-S-N-V-F-T-L-N-E-Y-V-G-D-T-Q-E-I-D-D-P-F-G-G-S-F-D-V-Y-E-Q-T-Y-T-K-I-Y-D-L-V-D-K-I-K-F-K-H-E"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-T-A-T-A-N-T-F-I-L-G-A-G-V-E-W-G-T-T-F-V-T-L-V-T-F-V-I-L-I-I-L-L-K-K-F-A-W-G-P-L-K-E-V-M-D-K-R-E-R-D-I-N-K-D-I-D-D-A-E-Q-A-K-I-N-A-Q-K-L-E-E-E-N-R-K-T-L-K-E-T-Q-D-E-V-Q-K-I-L-D-D-A-K-I-Q-A-R-K-Q-H-E-E-I-I-H-E-A-N-E-K-A-N-G-M-I-E-T-A-Q-S-E-I-N-S-Q-K-E-R-A-I-S-D-I-N-N-Q-V-S-E-L-S-V-L-I-A-S-K-V-L-R-K-E-I-S-E-Q-D-Q-K-E-L-V-E-K-Y-L-K-E-A-G-D-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-K-V-A-K-K-Y-A-K-A-L-F-D-V-A-L-D-T-N-Q-L-D-V-V-Y-E-D-L-E-T-I-S-H-S-S-F-D-F-I-K-Q-L-K-A-I-D-S-N-P-S-L-T-A-N-Q-R-E-E-F-V-E-R-V-Y-N-E-A-N-P-Y-V-V-N-T-L-K-V-L-A-D-N-R-H-I-S-I-V-E-N-V-F-K-S-F-Q-N-L-Y-N-K-Y-Y-K-Q-D-F-A-I-I-E-S-T-Y-E-L-S-E-D-E-I-S-R-I-V-E-L-I-K-K-Q-T-E-L-S-N-V-I-V-N-T-K-I-N-Q-D-L-I-G-G-F-R-V-K-V-G-T-T-V-M-D-G-S-V-R-N-D-L-V-Q-L-Q-R-K-F-E-R-A-N"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-Y-G-I-G-I-D-L-I-E-I-E-R-I-K-N-L-Q-N-Q-T-K-F-I-E-R-I-L-T-I-E-E-R-D-K-L-N-Q-Y-T-H-E-Q-R-R-L-E-F-L-A-G-R-F-T-V-K-E-A-F-S-K-A-L-G-T-G-L-G-K-S-V-S-F-Q-D-I-N-C-Y-N-D-A-L-G-K-P-C-I-D-Y-P-G-F-Y-T-H-V-S-I-T-H-T-E-N-Y-A-M-S-Q-V-I-L-E-K-N-E"} +{"text": "### FUNCTION Dephosphorylates the phosphotyrosine-containing proteins ### SEQUENCE -M-I-H-V-A-F-V-C-L-G-N-I-C-R-S-P-M-A-E-A-I-M-R-Q-R-L-Q-E-R-G-I-S-D-I-K-V-H-S-R-G-T-G-R-W-N-L-G-E-P-P-H-N-G-T-Q-K-I-L-Q-K-Y-H-I-P-Y-D-G-M-V-S-E-L-F-E-P-D-D-D-F-D-Y-I-I-A-M-D-Q-S-N-V-D-N-I-K-Q-I-N-P-N-L-Q-G-Q-L-F-K-L-L-E-F-S-N-M-E-E-S-D-V-P-D-P-Y-Y-T-N-N-F-E-G-V-F-E-M-V-Q-S-S-C-D-N-L-I-D-Y-I-V-K-D-A-N-L-K-E-R"} +{"text": "### FUNCTION Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins May act as a hydrogen peroxide and organic hydroperoxide sensor ### SEQUENCE -M-S-A-E-L-E-S-I-D-H-E-L-E-E-S-I-A-S-L-R-K-A-G-V-R-I-T-P-Q-R-Q-A-I-M-R-Y-L-I-S-S-H-S-H-P-T-A-D-E-I-Y-Q-A-L-S-P-K-F-P-N-I-S-V-A-T-I-Y-N-N-L-R-V-F-K-D-I-G-I-V-K-E-L-T-Y-G-D-S-S-S-R-F-D-F-N-T-H-N-H-Y-H-I-I-C-E-K-C-G-K-I-V-D-F-H-Y-P-Q-L-D-E-V-E-Q-L-A-Q-H-V-T-D-F-D-V-T-H-H-R-M-E-I-Y-G-V-C-K-E-C-K-E-E-G-N"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-V-N-D-F-K-T-G-L-T-I-S-V-D-N-G-I-W-K-V-I-D-F-Q-H-V-K-P-G-K-G-S-A-F-V-R-S-K-L-R-N-L-R-T-G-A-I-Q-E-K-T-F-R-A-G-E-K-V-E-Q-A-M-I-E-N-R-R-M-Q-Y-L-Y-A-D-G-D-N-H-V-F-M-D-N-E-T-F-N-Q-I-E-L-P-G-D-Y-L-K-D-E-L-N-Y-L-K-A-N-M-E-V-Q-V-Q-S-Y-E-S-E-V-I-G-V-E-L-P-K-T-V-E-L-E-V-T-E-T-E-P-G-I-K-G-D-T-A-T-G-A-T-K-S-A-T-V-E-T-G-Y-T-L-N-V-P-L-F-V-N-E-G-D-T-L-V-I-N-T-S-D-G-S-Y-I-S-R-G"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-R-K-D-A-R-V-Q-A-F-Q-T-L-F-Q-L-E-I-K-E-T-D-L-T-I-Q-E-A-I-E-F-I-K-D-D-H-S-D-L-D-F-D-F-I-Y-W-L-V-T-G-V-K-D-H-Q-I-V-L-D-E-T-I-K-P-H-L-K-D-W-S-I-D-R-L-L-K-S-D-R-I-I-L-R-M-A-T-F-E-I-L-H-S-D-T-P-K-K-V-V-V-N-E-A-V-E-L-T-K-Q-F-S-D-D-D-H-Y-K-F-V-N-G-V-L-S-N-I-N-D"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-S-K-E-K-Q-S-F-E-E-M-M-K-E-L-E-N-I-V-Q-K-L-D-N-E-A-V-S-L-E-E-S-L-D-L-Y-Q-R-G-M-K-L-S-A-N-C-D-S-T-L-K-E-A-E-K-K-V-N-E-L-M-Q-E-E-V-G-D-K-G-N-E-E-T-T-D-E"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-P-K-K-S-V-R-H-I-K-I-R-E-I-I-S-N-E-Q-I-E-T-Q-D-E-L-V-K-R-L-N-E-Y-D-L-N-V-T-Q-A-T-V-S-R-D-I-K-E-L-Q-L-I-K-V-P-A-P-T-G-Q-Y-V-Y-S-L-P-N-D-R-R-Y-H-P-L-E-K-L-G-R-Y-L-M-D-S-F-V-N-I-E-G-T-G-N-L-L-V-L-K-T-L-P-G-N-A-Q-S-I-G-A-I-L-D-Q-I-D-W-D-E-V-L-G-T-I-C-G-D-D-T-C-L-L-I-C-R-D-E-E-A-S-E-E-I-K-T-R-I-F-N-L-L"} +{"text": "### FUNCTION Involved in cold stress response ### SEQUENCE -M-K-Q-G-T-V-K-W-F-N-A-E-K-G-F-G-F-I-E-V-E-G-E-N-D-V-F-V-H-F-S-A-I-N-Q-E-G-Y-K-S-L-E-E-G-Q-S-V-E-F-E-V-V-E-G-D-R-G-P-Q-A-A-N-V-V-K-L"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-K-E-F-A-L-K-G-N-V-L-D-L-A-I-A-V-V-M-G-A-A-F-N-K-I-V-T-S-L-V-Q-Y-I-I-M-P-L-I-G-K-L-F-G-S-V-N-F-A-E-D-W-S-F-W-G-I-K-Y-G-L-F-I-Q-S-I-I-D-F-I-I-I-A-F-A-L-F-I-F-V-K-I-A-N-T-V-M-K-K-E-E-K-E-E-E-V-E-E-N-T-V-L-L-T-E-I-R-D-L-L-K-K"} +{"text": "### FUNCTION This protein catalyzes the committed step to the synthesis of the acidic phospholipids ### SEQUENCE -M-N-I-P-N-Q-I-T-V-F-R-V-I-L-I-P-F-F-I-L-F-A-L-V-D-F-G-F-G-Q-I-S-I-L-G-G-N-H-I-R-I-E-I-L-I-S-A-I-I-F-V-V-A-S-L-S-D-F-A-D-G-Y-L-A-R-K-W-Q-L-V-T-N-M-G-K-F-L-D-P-L-A-D-K-L-L-V-A-S-A-L-I-V-M-V-Q-L-G-F-T-N-S-V-V-A-I-I-I-I-A-R-E-F-A-V-T-G-L-R-L-L-Q-I-E-Q-G-F-V-S-A-A-G-Q-L-G-K-I-K-T-A-V-T-M-V-A-I-I-W-I-L-L-G-D-P-F-V-H-Y-L-R-F-P-I-G-V-W-L-L-Y-I-G-V-F-F-T-I-L-S-G-I-E-Y-F-Y-K-G-R-D-V-F-K-H-S-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-N-N-I-R-A-E-R-V-G-E-Q-M-K-Q-E-I-M-D-I-V-N-N-K-V-K-D-P-R-V-G-F-L-T-I-T-D-V-E-L-T-N-D-L-S-Q-A-K-V-Y-L-T-V-L-G-N-D-K-E-V-D-N-T-F-K-A-L-H-K-A-T-G-F-I-K-S-E-L-G-S-R-M-R-L-R-I-I-P-E-L-T-F-E-Y-D-E-S-I-E-Y-G-N-K-I-E-R-M-I-Q-E-L-H-K-N-D-K"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-V-E-V-G-Q-I-V-N-T-H-G-I-K-G-E-V-K-V-K-S-N-S-D-F-T-E-T-R-F-Q-P-G-E-Q-L-L-V-K-H-N-N-T-E-I-V-Y-T-V-A-S-Y-R-I-H-K-G-F-H-M-L-R-F-E-G-I-N-N-I-N-E-I-E-H-L-K-G-D-Y-I-Y-Q-E-R-D-H-Q-D-I-E-L-G-E-H-E-Y-Y-Y-S-D-I-I-G-C-T-V-F-K-D-D-D-T-P-I-G-R-V-I-N-I-F-E-T-G-A-N-D-V-W-V-V-K-G-E-K-E-Y-L-I-P-Y-I-E-D-V-V-K-D-I-D-I-E-T-K-T-I-K-I-T-P-M-E-G-L-L-D"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-E-N-F-D-K-V-K-D-I-I-V-D-R-L-G-V-D-A-D-K-V-T-E-D-A-S-F-K-D-D-L-G-A-D-S-L-D-I-A-E-L-V-M-E-L-E-D-E-F-G-T-E-I-P-D-E-E-A-E-K-I-N-T-V-G-D-A-V-K-Y-I-N-S-L-E-K"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-S-E-R-I-I-L-D-E-A-A-I-Q-R-T-I-T-R-I-A-H-E-I-L-E-Y-N-K-G-T-K-D-L-V-L-L-G-I-K-T-R-G-A-F-L-A-H-R-I-Q-D-K-I-N-S-I-E-Q-Q-L-V-P-T-G-T-I-D-I-T-H-F-R-D-D-V-D-K-V-V-Q-Q-A-D-Q-Y-A-F-D-I-N-V-D-I-N-N-K-V-V-V-I-I-D-D-V-L-Y-T-G-R-T-V-R-A-S-L-D-A-I-L-L-H-T-R-P-I-K-I-G-L-A-A-L-V-D-R-G-H-R-E-L-P-I-R-A-D-F-V-G-K-N-I-P-T-A-R-D-E-S-V-S-V-Y-L-E-E-I-D-D-R-N-A-V-V-I-E"} +{"text": "### FUNCTION Component of the thioredoxin-thioredoxin reductase system Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-A-I-V-K-V-T-D-S-D-F-D-S-K-I-E-S-G-V-K-L-V-D-F-W-A-T-W-C-G-P-C-K-M-I-A-P-V-L-E-E-L-A-G-D-Y-D-G-K-A-D-I-L-K-L-D-V-D-E-N-P-S-T-A-A-K-Y-E-V-M-S-I-P-T-L-I-V-F-K-D-G-E-P-V-D-K-V-V-G-F-Q-P-K-E-N-L-A-E-V-L-D-K-H-L"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-T-M-K-D-I-I-R-D-G-H-P-T-L-R-E-K-A-K-E-L-S-F-P-L-S-N-N-D-K-E-T-L-R-A-M-R-E-F-L-I-N-S-Q-D-E-E-T-A-K-R-Y-G-L-R-S-G-V-G-L-A-A-P-Q-I-N-E-P-K-R-M-I-A-V-Y-L-P-D-D-G-N-G-K-S-Y-D-Y-M-L-V-N-P-K-I-M-S-Y-S-V-Q-E-A-Y-L-P-T-G-E-G-C-L-S-V-D-E-N-I-P-G-L-V-H-R-H-H-R-V-T-I-K-A-Q-D-I-D-G-N-D-V-K-L-R-L-K-G-Y-P-A-I-V-F-Q-H-E-I-D-H-L-N-G-I-M-F-Y-D-Y-I-D-A-N-E-P-L-K-P-H-E-E-A-V-E-V"} +{"text": "### FUNCTION Catalyzes quinol oxidation with the concomitant reduction of oxygen to water ### SEQUENCE -M-N-T-I-V-K-H-T-V-G-F-I-A-S-I-V-L-T-L-L-A-V-F-V-T-L-Y-T-N-M-T-F-H-A-K-V-T-I-I-F-G-F-A-F-I-Q-A-A-L-Q-L-L-M-F-M-H-L-T-E-G-K-D-G-R-L-Q-S-F-K-V-I-F-A-I-I-I-T-L-V-T-V-I-G-T-Y-W-V-M-Q-G-G-H-S-S-H-L"} +{"text": "### FUNCTION Mnh complex is a Na excretion ### SEQUENCE -M-N-R-Q-Q-N-N-L-I-F-Q-Y-A-A-V-I-I-F-F-M-V-I-V-F-G-F-S-L-F-L-A-G-H-Y-T-P-G-G-G-F-V-G-G-L-L-F-A-S-A-L-L-V-I-T-I-A-Y-D-V-K-T-M-R-K-I-F-P-L-D-F-K-I-L-I-G-I-G-L-L-F-C-V-G-T-P-L-T-S-W-F-M-S-K-N-F-F-T-H-V-T-F-D-I-P-L-P-L-L-E-P-M-H-M-T-T-A-M-F-F-D-F-G-V-L-C-A-V-V-G-T-I-M-T-I-I-I-S-I-G-E-N-E"} +{"text": "### FUNCTION Mnh complex is a Na excretion ### SEQUENCE -M-E-I-I-M-I-F-V-S-G-I-L-T-S-I-S-V-Y-L-V-L-S-K-S-L-I-R-I-I-M-G-T-T-L-L-T-H-A-A-N-L-F-L-I-T-M-G-G-L-K-H-G-T-V-P-I-F-E-K-G-T-S-S-Y-V-D-P-I-P-Q-A-L-I-L-T-A-I-V-I-A-F-A-T-T-A-F-F-L-V-L-A-F-R-T-Y-K-E-L-G-T-D-N-V-E-L-M-K-G-A-P-E-D-D-R-E"} +{"text": "### FUNCTION Mnh complex is a Na excretion ### SEQUENCE -M-A-I-Q-F-V-I-N-L-L-V-S-V-I-W-L-L-V-T-N-S-Y-T-L-N-N-F-V-L-G-F-I-L-G-L-F-L-V-Y-L-L-H-R-V-L-P-G-Q-F-Y-L-V-R-I-Y-R-I-I-M-L-I-I-T-F-L-T-E-L-I-K-A-N-F-G-V-L-K-I-I-L-K-P-R-I-E-N-K-P-G-F-F-V-Y-E-T-E-L-E-R-D-W-Q-L-V-L-L-S-N-L-I-T-L-T-P-G-T-V-V-L-G-I-S-D-D-R-K-K-I-Y-I-H-S-I-D-F-S-T-K-E-E-E-I-Q-N-I-K-S-S-L-E-K-V-V-R-K-V-G-E-K"} +{"text": "### FUNCTION Mnh complex is a Na excretion ### SEQUENCE -M-P-F-K-I-F-I-I-T-A-L-I-I-V-V-L-S-M-L-A-M-L-I-R-V-I-L-G-P-S-L-A-D-R-V-V-A-L-D-A-I-G-L-Q-L-M-A-V-I-A-L-F-S-I-L-L-N-I-K-Y-M-L-V-V-I-L-M-V-G-I-L-A-F-L-G-T-A-V-F-S-K-F-M-D-E-G-K-V-I-K-H-D-S-N-D-R-H"} +{"text": "### FUNCTION Mnh complex is a Na excretion ### SEQUENCE -M-I-A-T-I-V-T-S-V-S-I-I-F-V-V-L-G-A-L-I-S-A-F-A-A-T-G-L-I-R-L-R-D-V-Y-S-R-A-H-A-A-G-K-A-A-T-L-G-A-M-F-L-L-F-G-A-F-L-Y-F-I-G-T-E-G-Y-V-N-M-Q-L-I-I-G-I-I-F-V-F-I-T-G-P-L-S-S-H-L-I-M-K-A-A-Y-N-I-K-T-P-Y-T-K-D-T-K-I-D-E-I-K-E-D-M-K-H-T-K-L"} +{"text": "### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-E-F-R-E-Q-V-L-D-L-L-A-E-V-A-E-N-N-I-V-K-E-N-P-D-V-E-I-F-E-E-G-I-I-D-S-F-Q-T-V-G-L-L-L-E-I-Q-N-K-L-D-I-E-V-S-I-M-D-F-D-R-D-E-W-A-T-P-N-K-I-V-E-A-L-E-E-L-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-V-P-S-E-F-K-Y-S-K-E-H-E-W-V-K-I-E-N-N-V-A-T-V-G-I-T-E-Y-A-Q-N-E-L-G-D-I-V-F-V-E-L-P-E-T-D-D-E-L-N-E-G-D-T-F-G-S-V-E-S-V-K-T-V-S-E-L-Y-A-P-I-S-G-K-I-V-E-V-N-E-E-L-E-D-S-P-E-F-V-N-E-S-P-Y-E-K-A-W-M-V-K-I-E-I-S-D-D-S-Q-L-E-E-L-L-S-A-D-Q-Y-S-E-M-I-G-E"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-K-S-K-S-P-G-T-L-A-E-N-R-K-A-R-H-D-Y-N-I-E-D-T-I-E-A-G-I-A-L-R-G-T-E-I-K-S-I-R-R-G-S-A-N-L-K-D-S-F-A-Q-V-R-R-G-E-M-Y-L-N-N-M-H-I-A-P-Y-E-E-G-N-R-F-N-H-D-P-L-R-T-R-K-L-L-L-H-K-K-E-I-Q-K-L-G-E-R-T-R-E-I-G-Y-S-I-I-P-L-K-L-Y-L-K-H-G-Q-C-K-V-L-L-G-V-A-R-G-K-K-K-Y-D-K-R-Q-A-L-K-E-K-A-V-K-R-D-I-D-R-A-V-K-A-R-Y"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-H-T-L-I-I-V-L-L-I-I-D-C-I-A-L-V-T-V-V-L-L-Q-E-G-K-S-N-G-L-S-G-A-I-S-G-G-A-E-Q-L-F-G-K-Q-K-Q-R-G-V-D-L-F-L-H-R-L-T-I-I-L-A-I-L-F-F-V-L-M-F-C-I-S-Y-L-G-M"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-V-V-Y-Y-S-F-S-G-N-V-R-R-F-I-S-R-A-G-I-K-D-T-F-E-I-T-Q-D-N-C-N-E-S-V-N-E-P-Y-I-L-V-T-G-T-I-G-F-G-E-V-P-Q-P-V-Q-S-F-L-N-V-N-H-T-Q-L-Q-A-V-A-A-S-G-N-R-N-W-G-Q-N-F-A-K-A-G-H-T-I-S-E-E-Y-K-V-P-L-M-M-K-F-E-V-Q-G-T-N-K-D-I-I-E-F-K-D-K-V-G-N-F-N-E-N-H-G-R-K-E-I-Q-S-Y"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-S-E-E-V-G-A-K-R-W-Y-A-V-H-T-Y-S-G-Y-E-N-K-V-K-K-N-L-E-K-R-V-E-S-M-N-M-T-E-Q-I-F-R-V-V-I-P-E-E-E-E-T-Q-V-K-D-G-K-A-K-K-L-V-K-K-T-F-P-G-Y-V-L-V-E-L-I-M-T-D-E-S-W-Y-V-V-R-N-T-P-G-V-T-G-F-V-G-S-A-G-A-G-S-K-P-N-P-L-L-P-E-E-V-R-F-I-L-K-Q-M-G-L-K-E-K-T-I-D-V-E-L-D-V-G-E-Q-V-R-I-Q-S-G-P-F-A-N-Q-I-G-E-V-Q-E-I-E-A-D-K-F-K-L-T-V-L-V-D-M-F-G-R-E-T-P-V-E-V-E-F-D-Q-I-E-K-L"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-A-K-K-E-S-F-F-K-G-V-K-S-E-M-E-K-T-S-W-P-T-K-E-E-L-F-K-Y-T-I-I-V-V-S-T-V-I-F-F-L-V-F-F-Y-A-L-D-I-G-I-N-A-L-K-Q-L-F-L-G"} +{"text": "### FUNCTION Catalyzes the reduction of arsenate ### SEQUENCE -M-D-K-K-T-I-Y-F-I-C-T-G-N-S-C-R-S-Q-M-A-E-G-W-G-K-K-I-L-G-D-E-W-Q-V-Y-S-G-G-I-E-A-H-G-V-N-P-K-A-I-E-A-M-K-E-V-G-I-D-I-S-N-H-T-S-N-L-I-D-Q-N-I-L-H-Q-S-D-L-V-V-T-L-C-S-D-A-D-K-N-C-P-I-L-P-P-S-V-K-K-E-H-W-G-F-D-D-P-A-G-K-P-W-S-E-F-Q-R-V-R-D-E-I-K-T-A-I-E-S-F-K-T-R"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-T-Y-E-I-M-Y-I-V-R-P-N-I-E-E-D-A-K-K-A-L-V-E-R-F-N-G-I-L-A-S-E-G-S-E-V-L-E-E-K-D-W-G-K-R-R-L-A-Y-E-I-N-D-F-K-E-G-F-Y-N-I-V-R-I-K-T-D-N-N-K-S-T-D-E-F-Q-R-L-A-K-I-N-D-D-I-I-R-Y-I-V-I-R-E-D-Q-D-K"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-G-G-P-R-R-G-G-R-R-R-K-K-V-C-Y-F-T-A-N-G-I-T-H-I-D-Y-K-D-T-E-L-L-K-R-F-I-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-Y-Q-R-M-L-T-T-A-I-K-R-A-R-H-M-A-L-L-P-Y-V-K-E-E-Q"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-R-G-G-G-N-M-Q-Q-M-M-K-Q-M-Q-K-M-Q-K-K-M-A-Q-E-Q-E-K-L-K-E-E-R-V-A-G-T-A-G-G-G-M-V-T-V-T-V-T-G-H-K-E-V-V-D-V-E-I-K-E-E-A-V-D-P-E-D-I-E-M-L-Q-D-L-V-L-A-A-T-N-E-A-M-N-K-A-D-E-L-T-Q-Q-R-L-G-K-H-T-Q-G-L-N-I-P-G-M"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-R-N-E-L-F-E-R-L-M-K-L-E-H-H-V-E-Q-L-T-T-D-M-S-E-L-K-D-L-T-V-E-L-V-E-E-N-V-A-L-Q-V-E-N-E-N-L-K-R-L-M-N-K-T-E-E-S-V-E-T-H-L-D-K-D-N-Y-K-H-V-K-T-P-S-P-S-K-D-N-L-A-M-L-Y-R-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-L-C-L-N-V-L-S-D"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-C-I-V-G-L-G-N-I-G-K-R-F-E-L-T-R-H-N-I-G-F-E-V-V-D-D-I-L-E-R-H-Q-F-T-L-D-K-Q-K-F-K-G-A-Y-T-I-E-R-L-N-G-E-K-V-L-F-I-E-P-M-T-M-M-N-L-S-G-Q-A-V-A-P-L-M-D-Y-Y-N-V-D-V-E-D-L-I-V-L-Y-D-D-L-D-L-E-Q-G-Q-V-R-L-R-Q-K-G-S-A-G-G-H-N-G-M-K-S-I-I-K-M-L-G-T-D-Q-F-K-R-I-R-I-G-V-G-R-P-T-N-G-M-S-V-P-D-Y-V-L-Q-K-F-S-K-E-E-M-I-I-M-E-K-V-I-E-H-S-A-R-A-V-E-S-F-I-E-S-S-R-F-D-H-V-M-N-E-F-N-G-E-V-K"} +{"text": "### FUNCTION Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation Inhibited by the antiholin-like proteins LrgAB In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential ### SEQUENCE -M-E-K-A-K-F-V-I-K-L-I-L-Q-L-A-L-I-M-L-I-T-F-I-G-T-E-V-Q-K-L-L-H-I-P-L-A-G-S-I-V-G-L-M-L-F-F-L-L-L-Q-F-K-I-V-P-E-S-W-I-N-V-G-A-D-F-L-L-K-T-M-V-F-F-F-I-P-S-V-V-G-I-M-D-V-A-S-N-I-T-M-N-Y-I-L-F-F-I-V-I-I-I-G-T-C-L-V-A-L-S-S-G-Y-I-A-E-K-M-L-E-K-S-N-T-R-K-G-T-D-H-S"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-E-A-R-D-V-L-K-R-P-V-I-T-E-K-S-S-E-A-M-A-E-D-K-Y-T-F-D-V-D-T-R-A-N-K-T-Q-V-K-I-A-V-E-E-I-F-D-V-K-V-D-S-V-N-I-I-N-Y-K-P-K-K-K-R-M-G-R-Y-Q-G-Y-T-N-K-R-R-K-A-I-V-K-L-K-E-G-S-I-D-L-F-N"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-I-K-K-G-P-F-V-D-D-H-L-M-K-K-V-E-A-Q-D-G-S-E-K-K-Q-V-I-K-T-W-S-R-R-S-T-I-F-P-N-F-I-G-H-T-F-A-V-Y-D-G-R-K-H-V-P-V-Y-V-T-E-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-K-G-H-A-A-D-D-K-K-T-R-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-V-A-R-T-I-R-I-A-P-R-K-V-R-L-V-L-D-L-I-R-G-K-N-A-G-E-A-I-A-I-L-K-L-T-N-K-A-S-S-P-V-I-E-K-V-L-M-S-A-L-A-N-A-E-H-N-Y-D-M-N-T-D-E-L-V-V-K-E-A-Y-A-N-E-G-P-T-L-K-R-F-R-P-R-A-Q-G-R-A-S-A-I-N-K-R-T-S-H-I-T-I-V-V-S-D-G-K-E-E-A-K-E-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-L-P-K-R-V-K-Y-R-R-Q-H-R-P-K-T-T-G-R-S-K-G-G-N-Y-V-T-F-G-E-Y-G-L-Q-A-T-T-T-S-W-I-T-S-R-Q-I-E-S-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-T-P-Y-T-K-K-P-L-E-V-R-M-G-A-G-K-G-A-V-E-G-W-I-A-V-V-K-P-G-R-I-L-F-E-V-A-G-V-P-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-S-K-F-V-K-R-E-E-L-G-G-E-T-N-E-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-R-N-D-R-K-V-Y-V-G-R-V-V-S-D-K-M-D-K-T-V-T-V-L-V-E-T-Y-K-T-H-K-L-Y-G-K-R-V-K-Y-S-K-K-Y-K-T-H-D-E-N-N-S-A-K-L-G-D-I-V-K-I-Q-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-I-V-E-E-S-V-I-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-K-V-A-D-N-S-G-A-R-E-V-L-T-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-I-I-V-C-T-V-K-N-A-T-P-G-G-V-V-K-K-G-D-V-V-K-A-V-V-V-R-T-K-S-G-V-R-R-E-D-G-S-Y-I-K-F-D-E-N-A-C-V-I-I-R-D-D-K-G-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-H-I-K-K-G-D-N-V-K-V-I-A-G-K-D-K-G-K-E-G-K-V-V-A-T-E-P-K-K-D-R-V-V-V-E-G-V-N-V-I-K-K-H-Q-K-P-T-Q-L-N-P-E-G-G-I-L-E-T-E-A-A-I-H-V-S-N-V-Q-L-L-D-P-K-T-N-E-P-T-R-V-G-Y-K-T-V-D-G-K-K-V-R-I-A-K-K-S-G-E-E-I-K-A-N-N"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-E-K-F-N-T-E-V-T-E-N-L-V-K-K-F-N-Y-S-S-V-M-E-V-P-K-I-E-K-I-V-V-N-M-G-V-G-D-A-V-Q-N-S-K-V-L-D-N-A-V-E-E-L-E-L-I-T-G-Q-K-P-L-V-T-K-A-K-K-S-V-A-T-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-I-A-V-S-L-P-R-V-R-D-F-Q-G-V-S-K-T-A-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-D-Y-D-K-V-T-K-V-R-G-M-D-I-V-I-V-T-T-A-N-T-D-E-E-A-R-E-L-L-T-N-F-G-M-P-F-R-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-S-M-V-A-K-Q-Q-K-K-Q-K-F-A-V-R-E-Y-T-R-C-E-R-C-G-R-P-H-S-V-Y-R-K-F-K-L-C-R-I-C-F-R-E-L-A-Y-K-G-Q-I-P-G-V-R-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-I-A-D-M-L-T-R-V-R-N-A-N-M-V-R-H-E-K-L-E-L-P-A-S-N-I-K-K-E-I-A-E-I-L-K-S-E-G-F-I-K-N-V-E-Y-V-E-D-D-K-Q-G-V-I-R-L-F-L-K-Y-G-Q-N-N-E-R-V-I-T-G-L-K-R-I-S-K-P-G-L-R-V-Y-A-K-A-N-E-V-P-K-V-L-N-G-L-G-I-A-L-V-S-T-S-E-G-V-I-T-D-K-E-A-R-K-R-N-V-G-G-E-I-I-A-Y-V-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-K-I-I-D-I-P-S-D-V-T-V-T-F-D-G-S-H-V-T-V-K-G-P-K-G-E-L-E-R-T-L-N-E-R-M-T-F-K-Q-E-E-N-T-V-E-V-V-R-P-S-D-S-K-E-D-R-T-D-H-G-T-T-R-A-L-L-N-N-M-V-L-G-V-S-Q-G-Y-E-K-T-L-E-L-V-G-V-G-Y-R-A-Q-M-Q-G-K-D-L-V-L-N-V-G-Y-S-H-P-V-E-I-K-A-E-E-G-I-T-F-A-V-E-K-N-T-T-V-K-V-S-G-V-S-K-E-Q-V-G-A-I-A-S-N-I-R-S-V-R-P-P-E-P-Y-K-G-K-G-I-R-Y-Q-G-E-Y-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-I-D-K-N-K-V-R-L-K-R-H-A-R-V-R-T-K-L-S-G-T-A-E-K-P-R-L-N-V-Y-R-S-N-K-H-I-Y-A-Q-I-I-D-D-V-K-G-V-T-L-A-Q-A-S-S-Q-D-K-D-I-A-N-T-S-A-S-K-V-D-L-A-T-T-V-G-Q-E-I-A-K-K-A-N-D-K-G-I-K-E-I-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-N-G-L-E-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-R-R-E-E-E-T-K-E-F-E-E-R-V-V-T-I-N-R-V-A-K-V-V-K-G-G-R-R-F-R-F-T-A-L-V-V-V-G-D-K-N-G-R-V-G-F-G-T-G-K-A-Q-E-V-P-E-A-I-K-K-A-V-E-A-A-K-K-D-L-V-V-V-P-R-V-E-G-T-T-P-H-T-I-T-G-Q-Y-G-S-G-S-V-F-M-K-P-A-A-P-G-T-G-V-I-A-G-G-P-V-R-A-V-L-E-L-A-G-I-T-D-I-L-S-K-S-L-G-S-N-T-P-I-N-M-V-R-A-T-I-N-G-L-Q-N-L-K-N-A-E-D-V-A-K-L-R-G-K-S-V-E-E-L-Y-N"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-A-A-E-G-S-R-R-V-R-N-R-V-G-R-G-A-A-T-G-N-G-K-T-S-G-R-G-Q-K-G-Q-K-A-R-S-G-G-K-V-R-P-G-F-E-G-G-Q-L-P-L-F-R-R-L-P-K-R-G-F-T-N-I-N-R-K-E-Y-A-I-V-N-L-D-Q-L-N-K-F-E-D-G-T-E-V-T-P-A-L-L-V-E-S-G-V-V-K-N-E-K-S-G-I-K-V-L-G-N-G-S-L-D-K-K-L-T-V-K-A-H-K-F-S-A-S-A-A-E-A-I-D-A-K-G-G-A-H-E-V-I"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-Q-D-V-I-E-L-E-G-T-V-L-D-T-L-P-N-A-M-F-K-V-E-L-E-N-G-H-E-I-L-A-H-V-S-G-K-I-R-M-N-Y-I-R-I-L-P-G-D-K-V-T-V-E-M-S-P-Y-D-L-S-R-G-R-I-T-Y-R-Y-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-I-P-R-E-K-R-I-V-I-S-L-T-Y-V-Y-G-I-G-T-S-T-A-N-K-I-V-E-E-A-N-V-S-A-D-T-R-V-K-D-L-T-D-D-E-L-G-R-I-R-E-V-V-D-G-Y-K-V-E-G-D-L-R-R-E-Q-N-L-N-I-K-R-L-M-E-I-S-S-Y-R-G-I-R-H-R-R-G-L-P-V-R-G-Q-K-T-K-N-N-A-R-T-R-K-G-P-V-K-T-V-A-N-K-K-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-Q-T-F-M-A-N-E-S-N-I-E-R-K-W-Y-V-I-D-A-E-G-Q-T-L-G-R-L-S-S-E-V-A-A-I-L-R-G-K-N-K-V-T-Y-T-P-H-V-D-T-G-D-Y-V-I-I-I-N-A-S-K-I-E-F-T-G-N-K-E-Q-D-K-M-Y-H-R-H-S-N-H-P-G-G-L-K-S-I-S-A-G-E-L-K-R-T-N-P-E-R-L-L-E-T-S-I-K-G-M-L-P-S-T-R-L-G-E-K-Q-G-K-K-L-F-V-Y-G-G-A-E-H-P-H-A-A-Q-Q-P-E-N-Y-E-L-R-G"} +{"text": "### FUNCTION Involved in multidrug efflux ### SEQUENCE -M-K-F-L-K-N-K-S-Y-H-L-L-V-T-L-I-V-L-T-I-F-V-I-S-G-A-I-F-L-T-F-L-G-F-G-L-Y-G-L-S-R-I-L-I-Y-L-H-L-G-D-F-S-Y-N-K-G-F-Y-D-N-L-I-Y-Y-G-S-Y-I-V-L-G-Y-F-T-L-F-S-I-E-H-L-M-D-Y-F-K-K-N-L-P-K-N-P-Y-F-Q-G-I-N-F-H-L-I-S-Y-I-V-T-T-I-M-F-Y-F-I-V-H-I-H-Y-V-H-V-N-I-H-F-W-V-I-M-I-I-I-G-F-L-F-V-C-K-E-V-F-Y-P-E-S-K-N-L-N-N-K-K"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-K-I-Q-D-Y-T-K-E-M-V-D-E-K-S-F-I-D-M-A-Y-T-L-L-N-D-K-Q-T-T-M-N-L-Y-D-I-I-D-E-F-K-S-L-G-G-Y-E-Y-E-D-I-E-N-R-I-V-Q-F-Y-T-D-L-N-T-D-G-R-F-L-N-V-G-E-N-L-W-G-L-R-D-W-Y-S-V-D-D-I-E-E-K-I-A-P-T-I-Q-K-F-D-I-L-D-D-E-D-E-E-D-Q-N-L-K-L-L-G-D-D-D-A-D-E-D-D-D-I-P-A-Q-T-D-D-Q-E-T-L-D-E-S-D-N-D-E-D-D-V-E-M-N-E-A-D-I-V-I-D-E-D-E-D-E-D-I-A-E-G-E-E-E-A-F-E-D-A-E-D-F-N-D"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity ### SEQUENCE -M-L-S-F-N-Q-N-R-N-H-S-L-E-Q-S-L-K-E-G-Y-A-Q-M-A-D-L-N-L-S-L-A-T-E-A-F-P-I-E-C-E-A-C-D-C-N-E-S-H-L-I-S-N-S-K-N-E"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA Neutralized by coexpression with cognate antitoxin MazE ### SEQUENCE -M-I-R-R-G-D-V-Y-L-A-D-L-S-P-V-Q-G-S-E-Q-G-G-V-R-P-V-V-I-I-Q-N-D-T-G-N-K-Y-S-P-T-V-I-V-A-A-I-T-G-R-I-N-K-A-K-I-P-T-H-V-E-I-E-K-K-K-Y-K-L-D-K-D-S-V-I-L-L-E-Q-I-R-T-L-D-K-K-R-L-K-E-K-L-T-F-L-S-E-S-K-M-I-E-V-D-N-A-L-D-I-S-L-G-L-N-N-F-D-H-H-K-S"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-T-K-V-T-R-E-E-V-E-H-I-A-N-L-A-R-L-Q-I-S-P-E-E-T-E-E-M-A-N-T-L-E-S-I-L-D-F-A-K-Q-N-D-S-A-D-T-E-G-I-E-P-T-Y-H-V-L-D-L-Q-N-V-L-R-D-D-K-A-I-E-G-I-P-Q-E-L-A-L-K-N-A-K-E-T-E-D-G-Q-F-K-V-P-S-I-M-N-G-E-D-A"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-T-I-L-L-V-M-L-G-G-G-I-G-A-V-L-R-A-L-I-T-N-I-C-Q-R-L-F-N-S-K-I-P-I-A-T-S-I-V-N-I-T-G-S-L-I-I-G-F-M-M-G-H-A-L-D-S-H-H-M-F-P-F-F-V-T-G-V-L-G-G-L-T-T-F-S-T-L-S-S-E-L-V-N-M-L-S-P-Q-F-K-P-I-R-F-V-V-Y-S-L-L-Q-F-I-L-G-F-I-A-C-F-Y-G-Y-R-I"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Q-Y-L-Y-I-F-V-G-G-A-L-G-A-L-I-R-F-C-L-S-M-L-N-E-G-S-T-I-P-L-G-T-F-V-A-N-L-L-G-A-F-L-M-G-S-I-G-A-L-S-L-S-L-F-K-T-H-P-N-I-K-K-G-L-T-T-G-L-L-G-A-L-T-T-F-S-T-F-Q-F-E-L-V-T-L-F-N-Q-H-H-F-I-L-F-T-I-Y-G-V-T-S-Y-I-L-G-I-L-S-C-Y-L-G-V-K-I-G-G-R-F-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-R-F-R-G-S-N-W-K-K-S-R-R-L-G-I-S-L-S-G-T-G-K-E-L-E-K-R-P-Y-A-P-G-Q-H-G-P-N-Q-R-K-K-L-S-E-Y-G-L-Q-L-R-E-K-Q-K-L-R-Y-L-Y-G-M-T-E-R-Q-F-R-N-T-F-D-I-A-G-K-Q-Y-G-V-H-G-E-N-F-M-I-L-L-A-S-R-L-D-A-V-V-Y-S-L-G-L-A-R-T-R-R-Q-A-R-Q-L-V-N-H-G-H-I-E-V-D-G-G-R-V-D-I-P-S-Y-S-L-K-P-G-Q-V-I-T-V-R-E-K-S-Q-N-L-D-I-I-K-E-S-V-E-I-N-N-F-V-P-E-Y-L-D-F-D-A-D-N-L-K-G-T-F-V-R-F-P-E-R-S-E-L-P-A-E-I-N-E-Q-L-I-V-E-Y-Y-S-R"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-K-C-N-S-T-H-S-R-V-V-D-S-R-H-A-D-E-A-N-A-I-R-R-R-R-E-C-E-N-C-G-T-R-F-T-T-F-E-H-I-E-V-S-P-L-I-V-V-K-K-D-G-T-R-E-Q-F-L-R-E-K-I-L-N-G-L-V-R-S-C-E-K-R-P-V-R-Y-Q-Q-L-E-D-I-T-N-K-V-E-W-Q-L-R-D-E-G-Q-T-E-I-S-S-R-E-I-G-E-H-V-M-N-L-L-M-H-V-D-Q-V-S-Y-V-R-F-A-S-V-Y-K-E-F-K-D-V-D-Q-L-L-E-S-M-Q-G-I-L-S-D-N-K-R-S-D-K"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-T-I-A-K-D-Q-T-Q-I-N-E-K-I-R-A-K-E-L-R-L-I-G-Q-D-G-E-Q-I-G-V-K-S-K-R-E-A-L-E-M-A-E-R-V-D-L-D-L-V-V-V-A-P-N-A-K-P-P-V-A-R-I-M-D-Y-G-K-Y-K-F-E-Q-Q-K-K-E-K-E-M-K-K-K-Q-K-V-I-N-V-K-E-L-R-L-S-P-T-I-E-E-H-D-F-Q-T-K-L-K-N-G-R-K-F-L-S-K-G-D-K-C-K-V-S-I-R-F-R-G-R-A-I-T-H-K-E-I-G-Q-R-V-L-E-K-F-A-D-E-C-K-D-I-A-T-V-E-Q-K-P-K-M-E-G-R-Q-M-F-I-M-L-A-P-I-N-E-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-G-G-T-V-T-R-A-R-R-K-K-T-I-K-L-A-K-G-Y-F-G-S-K-H-T-L-Y-K-V-A-K-Q-Q-V-M-K-S-G-Q-Y-A-F-R-D-R-R-Q-R-K-R-D-F-R-K-L-W-I-T-R-I-N-A-A-A-R-Q-H-D-I-S-Y-S-R-L-M-N-G-L-K-K-A-E-I-D-I-N-R-K-M-L-S-E-I-A-I-S-D-D-K-A-F-A-E-L-V-S-K-A-K-E-A-L-K"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-N-I-N-F-N-N-I-N-L-I-I-S-A-V-K-K-A-Q-Y-P-D-T-G-L-T-E-V-A-L-S-G-R-S-N-V-G-K-S-T-F-I-N-S-M-I-G-R-K-N-M-A-R-T-S-Q-Q-P-G-K-T-Q-T-L-N-F-Y-N-I-D-E-Q-L-I-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-V-Q-R-E-K-F-G-K-M-I-E-E-Y-I-T-Q-R-E-N-L-K-L-V-I-Q-L-V-D-L-R-H-Q-P-T-E-D-D-V-L-M-Y-N-Y-L-K-H-F-D-I-P-T-L-V-I-C-T-K-E-D-K-I-A-K-G-K-V-Q-K-H-I-K-R-I-K-D-K-L-E-L-E-S-G-D-N-I-I-S-Y-S-S-I-K-N-S-K-Q-Q-E-I-W-N-F-I-E-T-Y-I"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-I-I-E-T-G-G-K-Q-I-K-V-E-E-G-Q-E-I-Y-V-E-K-L-N-A-N-E-G-D-S-F-T-F-D-K-V-L-F-V-G-G-D-S-V-K-V-G-A-P-T-V-E-G-A-S-V-T-A-T-V-N-K-Q-G-R-G-K-K-I-T-V-F-T-Y-K-R-R-K-D-S-K-R-K-K-G-H-R-Q-P-Y-T-K-L-T-I-D-K-I-N-A"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-A-Y-I-K-G-T-L-S-Q-L-F-P-T-H-V-V-V-E-T-C-G-I-G-Y-E-I-Q-T-P-N-S-Y-R-F-Q-K-Y-L-E-K-E-V-Q-I-Y-T-S-L-I-V-R-E-D-A-Q-L-L-Y-G-F-I-N-E-E-E-K-E-M-F-L-S-L-I-K-V-T-G-I-G-P-K-S-A-L-A-I-L-A-S-S-T-P-H-E-V-K-L-A-I-E-N-E-N-D-A-Y-L-T-Q-F-P-G-I-G-K-K-T-A-R-Q-I-V-L-D-L-K-G-K-V-T-I-T-E-E-N-S-D-D-L-L-Q-T-Q-V-N-G-N-E-Q-N-Q-I-I-S-E-A-L-L-A-L-Q-A-L-G-Y-S-K-R-E-L-T-K-V-E-K-S-L-N-K-H-N-V-N-S-V-D-E-A-V-K-I-G-L-Q-T-L-V-S"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-K-Q-Y-V-S-E-V-K-D-W-P-S-A-G-V-S-F-K-D-I-T-T-I-M-D-N-G-E-A-Y-G-Y-A-T-D-Q-I-V-E-Y-A-K-E-K-N-I-D-I-V-V-G-P-E-A-R-G-F-I-I-G-C-P-V-A-Y-S-M-G-I-G-F-A-P-V-R-K-E-G-K-L-P-R-E-V-I-R-Y-E-Y-N-L-E-Y-G-T-N-V-L-T-M-H-K-D-A-I-K-P-G-Q-R-V-L-I-T-D-D-L-L-A-T-G-G-T-I-E-A-A-I-K-L-V-E-Q-L-G-G-I-V-V-G-I-A-F-I-I-E-L-K-Y-L-N-G-I-D-K-I-K-D-Y-D-V-M-S-L-I-S-Y-D-E"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-L-K-H-K-I-L-G-L-D-V-G-S-K-T-V-G-I-A-I-S-D-L-M-G-W-T-A-Q-G-L-D-T-L-R-I-N-E-E-Q-D-D-L-G-I-D-Q-L-V-K-I-I-K-D-N-Q-V-G-T-V-V-I-G-L-P-K-N-M-N-N-S-I-G-F-R-G-E-A-S-I-K-Y-K-E-K-L-Q-E-S-I-P-S-I-D-I-V-M-W-D-E-R-L-S-T-M-A-A-E-R-S-L-L-E-A-D-V-S-R-Q-K-R-K-K-V-I-D-K-M-A-A-V-F-I-L-Q-G-Y-L-D-S-I-Q"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-E-N-Q-K-Q-Y-P-M-T-Q-E-G-Y-E-K-L-E-Q-E-L-E-E-L-K-T-V-K-R-P-E-V-V-E-K-I-K-V-A-R-S-F-G-D-L-S-E-N-S-E-Y-D-A-A-K-D-E-Q-G-F-I-E-Q-D-I-Q-R-I-E-H-M-I-R-N-A-L-I-I-E-D-N-G-D-N-N-V-V-Q-I-G-K-T-V-T-F-I-E-L-P-G-D-E-E-E-S-Y-Q-I-V-G-S-A-E-A-D-A-F-K-G-K-I-S-N-E-S-P-M-A-K-A-L-I-G-K-G-L-N-D-Q-V-R-V-P-L-P-N-G-G-E-M-N-V-K-I-V-E-I-K"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-N-K-K-I-V-L-F-G-G-Q-F-N-P-I-H-T-A-H-L-A-V-A-S-E-V-Y-H-A-I-K-P-D-I-F-F-F-L-P-S-Y-M-A-P-L-K-H-H-N-T-Q-L-Y-S-E-H-R-V-K-M-I-Q-L-A-I-K-E-I-G-F-G-E-I-C-T-T-D-L-D-R-K-G-P-S-Y-T-Y-E-T-I-L-H-L-K-E-I-Y-H-N-A-Q-L-Y-F-I-I-G-T-D-Q-Y-N-Q-L-D-K-W-Y-K-I-N-E-L-K-K-L-V-T-F-I-V-V-N-R-E-T-D-N-Q-N-V-S-K-E-M-I-S-I-K-I-P-R-I-D-I-S-S-T-M-I-R-N-R-V-R-M-N-Q-S-I-K-V-L-V-P-K-R-V-E-N-Y-I-K-E-E-G-F-Y-G-D-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-N-I-K-S-A-I-K-R-V-R-T-T-E-T-A-E-E-R-N-I-S-K-K-N-A-M-R-T-A-V-K-R-A-K-T-A-I-S-T-D-A-E-N-K-D-E-L-L-R-F-A-I-K-Q-V-D-K-A-S-Q-S-N-L-I-H-S-N-K-A-D-R-I-K-S-K-L-M-S-A-N-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-F-T-I-D-F-S-D-H-T-G-L-V-E-T-S-W-F-D-Q-I-D-Q-L-L-T-F-A-K-K-K-E-N-I-H-N-D-A-E-L-S-V-T-F-V-D-K-D-E-I-Q-N-I-N-K-V-Y-R-D-K-D-K-V-T-D-V-I-S-F-A-L-E-E-D-E-P-E-I-D-F-N-D-F-D-I-P-R-V-L-G-D-I-I-I-C-T-D-V-A-K-E-Q-S-E-S-Y-G-H-S-F-E-R-E-L-G-F-L-A-L-H-G-F-L-H-L-L-G-Y-D-H-M-N-D-N-D-E-K-E-M-F-G-R-Q-D-A-I-L-N-E-F-G-L-T-R-N"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-S-D-V-S-L-K-L-S-A-K-D-I-Y-E-K-D-F-E-K-T-M-A-R-G-Y-R-R-E-E-V-D-A-F-L-D-D-I-I-T-D-Y-Q-K-M-A-D-M-N-N-E-V-V-K-L-S-E-E-N-H-K-L-K-K-E-L-E-E-L-R-L-R-V-A-T-S-R-P-Q-D-N-K-N-F-S-S-N-N-S-S-S-A-S-N-N-V-D-I-L-K-R-I-S-N-L-E-K-A-V-F-G-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-E-Q-K-R-Q-E-L-V-N-K-Y-Y-E-L-R-K-E-L-K-A-K-G-D-Y-E-A-L-R-K-L-P-R-D-S-S-P-T-R-L-T-R-R-C-K-V-T-G-R-P-R-G-V-L-R-K-F-E-M-S-R-I-A-F-R-E-H-A-H-K-G-Q-I-P-G-V-K-K-S-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-Q-Q-R-K-D-E-L-I-K-E-Y-R-V-H-E-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-A-E-I-T-A-L-N-E-H-L-R-E-H-K-K-D-H-H-S-R-R-G-L-L-K-M-V-G-R-R-R-H-L-L-N-Y-L-R-S-K-D-I-Q-R-Y-R-E-L-I-K-S-L-G-I-R-R"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-K-I-T-E-Q-V-E-A-L-I-Q-P-V-L-N-D-L-N-F-E-L-V-D-I-E-Y-V-K-E-G-K-D-H-F-L-R-I-S-I-D-K-E-G-G-V-D-L-N-D-C-T-I-A-S-E-K-I-S-E-V-M-D-E-N-D-P-I-P-E-M-Y-Y-L-D-V-A-S-P-G-A-E-R-P-I-K-K-E-K-D-F-Y-N-A-I-N-Q-P-I-F-V-S-L-Y-A-P-I-E-G-D-K-E-W-L-G-V-L-K-S-V-N-D-E-S-I-N-M-E-V-K-E-K-A-K-T-K-E-I-E-I-P-R-N-K-I-A-K-A-R-H-A-V-M-I"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-D-I-I-K-D-T-K-S-R-M-Q-K-S-I-D-N-L-S-R-E-L-A-N-I-S-A-G-R-A-N-S-N-L-L-N-G-V-T-V-D-Y-Y-G-A-P-T-P-V-Q-Q-L-A-S-I-N-V-P-E-A-R-L-L-V-I-S-P-Y-D-K-S-S-V-A-D-I-E-K-A-I-I-A-A-N-L-G-V-N-P-T-S-D-G-E-V-I-R-I-S-V-P-A-L-T-E-E-R-R-K-E-L-V-K-E-V-K-K-I-G-E-D-A-K-V-S-I-R-N-I-R-R-D-I-N-D-Q-L-K-K-D-E-K-N-G-D-I-T-E-D-D-L-R-S-Q-T-D-D-V-Q-K-A-T-D-N-S-I-K-E-I-D-Q-L-V-A-D-K-E-K-D-I-M-S-V"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-N-H-K-L-I-E-A-V-T-K-S-Q-L-R-T-D-L-P-T-F-R-S-G-D-T-L-R-V-H-V-R-I-V-E-G-S-R-E-R-I-Q-V-F-E-G-V-V-I-K-R-R-G-G-G-I-S-E-T-F-T-V-R-K-I-S-S-G-V-G-V-E-R-T-F-P-L-H-T-P-K-I-E-K-I-E-V-K-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-S-L-R-G-K-A-A-R-I-Q-E-I-R"} +{"text": "### FUNCTION Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism ### SEQUENCE -M-K-L-K-K-N-D-R-R-V-A-I-K-E-A-I-E-L-N-P-F-I-T-D-Y-E-L-C-E-K-F-D-V-S-I-Q-T-I-R-L-D-R-T-H-L-N-I-P-E-L-R-K-R-I-K-L-V-A-E-Q-N-Y-G-R-I-K-S-I-E-A-N-E-I-I-G-D-L-I-Q-V-N-P-D-V-S-A-Q-S-L-I-E-I-T-I-D-S-V-F-A-K-S-E-I-A-R-G-H-V-L-F-A-Q-A-N-S-L-C-V-A-L-I-H-K-P-I-V-L-T-H-E-S-Q-V-E-F-K-E-K-V-K-L-N-D-T-V-R-A-D-A-R-V-I-D-I-T-D-K-H-Y-I-I-E-V-N-S-Y-V-S-D-M-L-V-F-K-G-K-F-K-M-Y-Y-T-S-E-D-E"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-L-N-P-P-L-N-Q-L-T-A-K-V-N-S-K-Y-L-I-A-T-T-A-A-K-R-A-R-E-L-D-E-R-R-E-T-A-L-L-D-Q-Y-H-S-S-K-P-V-G-K-A-L-E-E-I-A-D-G-K-I-E-P-V-V-P-K-E-Y-L-G"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-A-V-F-K-V-F-Y-Q-H-N-K-D-E-V-I-V-R-E-N-T-Q-T-I-Y-V-E-G-Q-T-E-E-Q-V-R-R-Y-L-K-D-R-N-F-N-I-E-F-I-T-K-L-E-G-A-H-L-E-Y-E-K-E-H-S-T-H-F-N-V-E-N-A-E"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-T-L-F-T-S-P-S-C-T-S-C-R-K-A-K-A-W-L-Q-E-H-D-I-P-Y-T-E-R-N-I-F-S-E-H-L-T-I-D-E-I-K-Q-I-L-K-M-T-E-D-G-T-D-E-I-I-S-T-R-S-K-T-Y-Q-K-L-N-V-D-I-D-S-L-P-L-Q-D-L-Y-S-I-I-Q-D-N-P-G-L-L-R-R-P-I-I-L-D-D-K-R-L-Q-V-G-Y-N-E-D-E-I-R-R-F-L-P-R-K-V-R-T-F-Q-L-Q-E-A-Q-R-L-V-D"} +{"text": "### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-T-N-Y-P-Q-L-N-K-E-I-Q-D-N-E-I-K-V-V-M-H-T-N-K-G-D-M-T-F-K-L-F-P-D-I-A-P-K-T-V-E-N-F-V-T-H-S-K-N-G-Y-Y-D-G-V-T-F-H-R-V-I-N-D-F-M-V-Q-G-G-D-P-T-A-T-G-M-G-G-E-S-I-Y-G-S-A-F-E-D-E-F-S-L-E-A-F-N-L-Y-G-A-L-S-M-A-N-A-G-P-N-T-N-G-S-Q-F-F-I-V-Q-M-K-E-V-P-E-N-M-L-S-Q-L-A-D-G-G-W-P-Q-P-I-V-E-A-Y-G-E-K-G-G-T-P-W-L-D-Q-K-H-T-V-F-G-Q-L-I-E-G-E-S-T-L-E-D-I-A-N-T-K-V-G-A-Q-D-K-P-V-Y-D-V-V-I-E-S-I-D-V-E-E"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-L-I-P-T-V-I-E-T-T-N-R-G-E-R-A-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-G-S-Q-I-D-D-N-V-A-N-S-I-V-S-Q-L-L-F-L-Q-A-Q-D-S-E-K-D-I-Y-L-Y-I-N-S-P-G-G-S-V-T-A-G-F-A-I-Y-D-T-I-Q-H-I-K-P-D-V-Q-T-I-C-I-G-M-A-A-S-M-G-S-F-L-L-A-A-G-A-K-G-K-R-F-A-L-P-N-A-E-V-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-T-E-I-E-I-A-A-N-H-I-L-K-T-R-E-K-L-N-R-I-L-S-E-R-T-G-Q-S-I-E-K-I-Q-Q-D-T-D-R-D-N-F-L-T-A-A-E-A-K-E-Y-G-L-I-D-E-V-M-E-P-E-K"} +{"text": "### FUNCTION Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase ### SEQUENCE -M-I-R-F-E-I-H-G-D-N-L-T-I-T-D-A-I-R-N-Y-I-E-E-K-V-G-K-L-E-R-Y-F-N-N-V-P-N-A-V-A-H-V-R-V-K-T-Y-S-N-S-T-T-K-I-E-V-T-I-P-L-K-D-V-T-L-R-A-E-E-R-H-D-D-L-Y-A-G-I-D-L-I-T-N-K-L-E-R-Q-V-R-K-Y-K-T-R-V-N-R-K-H-R-D-R-G-D-Q-D-I-F-V-A-E-V-Q-E-S-T-T-N-N-H-A-D-D-I-E-S-E-N-D-I-E-I-I-R-S-K-Q-F-S-L-K-P-M-D-S-E-E-A-V-L-Q-M-N-L-L-G-H-D-F-F-I-F-T-D-R-E-T-D-G-T-S-I-V-Y-R-R-K-D-G-K-Y-G-L-I-E-T-T-E"} +{"text": "### FUNCTION Dephosphorylates the 5' and 2'-phosphates of deoxyribonucleotides ### SEQUENCE -M-T-R-Q-R-I-A-I-D-M-D-E-V-L-A-D-T-L-G-A-V-V-K-A-V-N-E-R-A-D-L-N-I-K-M-E-S-L-N-G-K-K-L-K-H-M-I-P-E-H-E-G-L-V-M-D-I-L-K-E-P-G-F-F-R-N-L-D-V-M-P-H-A-Q-E-V-V-K-Q-L-N-E-H-Y-D-I-Y-I-A-T-A-A-M-D-V-P-T-S-F-H-D-K-Y-E-W-L-L-E-Y-F-P-F-L-D-P-Q-H-F-V-F-C-G-R-K-N-I-I-L-A-D-Y-L-I-D-D-N-P-K-Q-L-E-I-F-E-G-K-S-I-M-F-T-A-S-H-N-V-Y-E-H-R-F-E-R-V-S-G-W-R-D-V-K-N-Y-F-N-S-I-E-K"} +{"text": "### FUNCTION Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines Requires NADPH, but not NADH, as an electron donor for its activity ### SEQUENCE -M-K-G-L-I-I-I-G-S-A-Q-V-G-S-H-T-N-A-L-S-K-Y-L-K-G-Q-L-G-E-H-D-V-E-V-E-I-F-D-L-A-E-K-P-I-H-Q-L-D-F-A-G-T-T-Q-A-V-D-E-I-K-N-N-V-K-S-L-Q-N-K-A-M-E-A-D-F-L-I-L-G-T-P-N-Y-H-G-S-F-S-G-I-L-K-N-A-L-D-H-L-N-M-D-H-F-K-M-K-P-V-G-L-I-C-N-S-G-G-I-V-S-S-E-P-L-S-H-L-R-V-I-V-R-S-L-L-G-I-A-V-P-T-Q-I-A-T-H-D-S-D-Y-A-K-L-E-D-G-T-L-Y-L-E-D-N-E-F-Q-L-R-S-K-L-F-V-D-Q-I-V-S-F-V-T-N-S-P-Y-E-H-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-N-Q-E-Q-I-I-E-A-I-K-E-M-S-V-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-A-A-G-A-A-G-G-G-D-A-A-A-E-K-T-E-F-D-V-E-L-T-S-A-G-S-S-K-I-K-V-V-K-A-V-K-E-A-T-G-L-G-L-K-D-A-K-E-L-V-D-G-A-P-K-V-I-K-E-A-M-P-K-E-D-A-E-K-L-K-E-Q-L-E-E-V-G-A-S-V-E-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-A-I-I-E-A-K-K-Q-Q-V-D-T-I-A-E-Q-L-K-N-S-V-S-T-V-I-V-D-Y-R-G-L-T-V-A-E-V-T-E-L-R-S-Q-L-R-E-A-G-V-E-Y-K-V-Y-K-N-T-M-V-R-R-A-A-E-Q-A-G-I-E-G-L-D-E-F-L-T-G-P-T-A-I-A-T-S-T-E-D-V-V-A-P-A-K-V-I-A-G-F-A-K-E-H-E-A-L-E-V-K-T-G-V-M-E-G-N-V-I-S-A-E-E-V-K-T-V-G-S-L-P-S-H-D-G-L-V-S-M-L-L-S-V-L-Q-A-P-V-R-N-F-A-Y-A-V-K-A-V-G-E-Q-K-E-E-S-A-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-K-V-V-K-L-Q-I-P-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-A-G-V-N-I-M-G-F-C-K-E-F-N-A-R-T-Q-E-Q-A-G-L-I-I-P-V-E-I-S-V-Y-E-D-R-S-F-T-F-I-T-K-T-P-P-A-P-V-L-L-K-K-A-A-G-V-E-K-G-S-G-E-P-N-K-T-K-V-A-T-V-T-K-D-Q-V-R-E-I-A-Q-T-K-M-Q-D-L-N-A-A-D-E-E-A-A-M-R-I-I-E-G-T-A-R-S-M-G-I-T-V-Q"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-T-I-L-S-V-G-K-L-K-E-K-Y-W-K-Q-A-I-A-E-Y-E-K-R-L-G-P-Y-T-K-I-E-L-I-E-V-P-D-E-K-A-P-E-N-M-S-D-K-E-I-E-Q-V-K-E-K-E-G-Q-R-L-L-N-K-I-K-P-Q-S-T-V-I-T-L-E-I-K-G-K-M-L-S-S-E-G-L-A-K-E-L-Q-T-R-M-T-Q-G-Q-S-D-F-T-F-V-I-G-G-S-N-G-L-H-Q-D-V-L-Q-R-S-N-Y-A-L-S-F-S-N-M-T-F-P-H-Q-M-M-R-V-I-L-I-E-Q-I-Y-R-A-F-K-I-M-R-G-E-A-Y-H-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-T-Q-D-V-K-G-K-G-K-K-G-E-V-K-D-V-P-V-G-Y-A-N-N-F-L-L-K-N-K-Y-A-V-E-A-T-P-G-N-L-K-Q-L-E-Q-Q-N-K-R-A-E-A-D-R-Q-Q-E-I-D-D-A-K-A-L-K-E-Q-L-K-D-I-E-V-E-V-S-A-K-T-G-E-G-G-K-L-F-G-S-I-S-T-K-Q-I-A-E-A-L-K-K-Q-H-D-I-K-I-D-K-R-K-M-D-L-P-H-G-I-H-A-L-G-Y-T-N-V-P-V-K-L-D-K-E-V-E-G-T-I-R-V-H-T-V-E-Q"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-T-K-K-M-N-V-E-S-F-N-L-D-H-T-K-V-K-A-P-Y-V-R-L-V-G-V-T-E-G-A-N-G-D-K-V-H-K-Y-D-I-R-I-K-Q-P-N-K-A-H-M-E-M-P-G-L-H-S-L-E-H-L-M-A-E-N-I-R-N-H-S-D-A-V-L-D-I-G-P-M-G-C-Q-T-G-F-Y-L-S-L-I-N-H-D-D-Y-D-D-V-L-T-M-I-E-K-T-L-E-D-V-L-Q-A-T-E-V-P-A-C-N-E-V-Q-C-G-W-A-A-N-H-S-L-L-G-A-Q-E-I-A-K-E-M-L-N-E-K-A-S-W-S-E-V-F"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-W-K-E-F-K-E-F-A-F-K-G-N-I-I-D-L-A-V-A-V-V-I-G-G-A-F-G-A-I-V-T-S-F-V-E-N-I-I-T-P-L-M-G-V-I-V-G-G-V-D-F-T-T-L-K-V-T-V-G-E-A-E-I-L-Y-G-N-F-I-Q-S-F-V-D-F-I-I-I-A-F-S-I-F-L-A-I-K-F-L-V-K-F-K-R-Q-K-E-E-E-E-V-E-A-V-V-E-E-L-S-K-Q-E-E-L-L-T-E-I-R-D-L-L-K-E-Q-S-N-K-N"} +{"text": "### FUNCTION Electron-transport protein of unknown function ### SEQUENCE -M-R-K-S-L-L-A-I-L-A-V-S-S-L-V-F-S-S-A-S-F-A-A-D-L-E-D-N-M-E-T-L-N-D-N-L-K-V-V-E-K-A-D-N-A-V-Q-V-K-D-A-L-T-K-M-R-A-A-A-L-D-A-Q-K-A-T-P-P-K-L-E-G-K-S-P-D-S-P-E-M-K-D-F-R-H-G-F-D-I-L-V-G-Q-I-D-D-A-L-K-L-A-N-E-G-K-V-K-E-A-Q-A-A-A-E-Q-L-K-T-T-R-N-A-Y-H-Q-K-Y-R"} +{"text": "### FUNCTION Binds zinc Could be an important component of the zinc-balancing mechanism ### SEQUENCE -M-K-R-N-T-K-I-A-L-V-M-M-A-L-S-A-M-A-M-G-S-T-S-A-F-A-H-G-G-H-G-M-W-Q-Q-N-A-A-P-L-T-S-E-Q-Q-T-A-W-Q-K-I-H-N-D-F-Y-A-Q-S-S-A-L-Q-Q-Q-L-V-T-K-R-Y-E-Y-N-A-L-L-A-A-N-P-P-D-S-S-K-I-N-A-V-A-K-E-M-E-N-L-R-Q-S-L-D-E-L-R-V-K-R-D-I-A-M-A-E-A-G-I-P-R-G-T-G-M-G-Y-G-G-C-G-G-G-G-H-M-G-M-G-H-W"} +{"text": "### FUNCTION General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases ### SEQUENCE -M-K-T-I-L-P-A-V-L-F-A-A-F-A-T-T-S-A-W-A-A-E-S-V-Q-P-L-E-K-I-A-P-Y-P-Q-A-E-K-G-M-K-R-Q-V-I-Q-L-T-P-Q-E-D-E-S-T-L-K-V-E-L-L-I-G-Q-T-L-E-V-D-C-N-L-H-R-L-G-G-K-L-E-S-K-T-L-E-G-W-G-Y-D-Y-Y-V-F-D-K-V-S-S-P-V-S-T-M-M-A-C-P-D-G-K-K-E-K-K-F-V-T-A-Y-L-G-D-A-G-M-L-R-Y-N-S-K-L-P-I-V-V-Y-T-P-D-N-V-D-V-K-Y-R-V-W-K-A-E-E-K-I-D-N-A-V-V-R"} +{"text": "### FUNCTION Required for growth and/or survival at acidic conditions ### SEQUENCE -M-K-K-V-L-A-L-V-V-A-A-A-M-G-L-S-S-A-A-F-A-A-E-T-A-T-T-P-A-P-T-A-T-T-T-K-A-A-P-A-K-T-T-H-H-K-K-Q-H-K-A-A-P-A-Q-K-A-Q-A-A-K-K-H-H-K-N-A-K-A-E-Q-K-A-P-E-Q-K-A-Q-A-A-K-K-H-A-K-K-H-S-H-Q-Q-P-A-K-P-A-A-Q-P-A-A"} +{"text": "### FUNCTION Part of a cation efflux system that mediates resistance to copper and silver Binds one copper per polypeptide ### SEQUENCE -M-K-K-A-L-Q-V-A-M-F-S-L-F-T-V-I-G-F-N-A-Q-A-N-E-H-H-H-E-T-M-S-E-A-Q-P-Q-V-I-S-A-T-G-V-V-K-G-V-D-L-E-S-K-K-I-T-I-H-H-D-P-I-A-A-V-N-W-P-E-M-T-M-R-F-T-I-T-P-Q-T-K-M-S-E-I-K-T-G-D-K-V-A-F-N-F-V-Q-Q-G-N-L-S-L-L-Q-D-I-K-V-S-Q"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-N-D-K-L-I-V-E-R-Q-E-V-E-N-K-S-E-G-G-I-V-L-T-S-Q-S-V-K-K-S-N-R-G-K-V-I-A-A-G-L-G-K-R-L-E-N-G-E-R-A-S-M-E-V-K-V-G-D-V-V-I-F-N-D-G-Y-G-V-K-T-E-K-M-D-G-K-E-Y-L-I-L-S-E-S-D-V-L-A-I-V-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-E-R-Q-E-V-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-E-K-S-T-R-G-V-V-L-A-V-G-K-G-R-I-L-E-N-G-T-V-Q-P-L-D-V-K-V-G-D-T-V-I-F-A-E-S-Y-G-T-K-T-E-K-I-D-G-K-E-V-L-I-M-S-E-N-D-I-M-A-I-V-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-N-E-I-I-A-Q-Y-A-R-H-E-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-W-E-I-N-H-L-N-E-H-I-K-Q-H-K-K-D-H-A-T-Y-R-G-L-M-K-K-I-G-R-R-R-N-L-L-A-Y-L-R-K-N-D-V-N-R-Y-R-E-L-I-N-S-L-G-L-R-R"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-P-L-I-Q-S-L-T-E-G-Q-L-R-T-D-I-P-S-F-R-P-G-D-T-V-R-V-H-A-K-V-V-E-G-N-R-E-R-I-Q-I-F-E-G-V-V-I-A-R-K-G-A-G-I-S-E-N-Y-T-V-R-K-I-S-N-G-I-G-V-E-R-I-F-P-I-H-T-P-R-V-E-K-I-E-V-V-R-Y-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-Q-G-K-A-A-R-I-K-E-I-R-R"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-T-Y-A-I-I-K-T-G-G-K-Q-V-K-V-E-V-G-Q-A-V-Y-V-E-K-L-N-V-E-A-G-Q-E-V-T-F-N-E-V-V-L-V-G-G-E-N-T-V-V-G-T-P-L-V-A-G-A-T-V-V-G-T-V-E-K-Q-G-K-Q-K-K-V-V-T-Y-K-Y-K-P-K-K-G-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-N-A-I-N-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-A-E-L-N-V-K-Q-N-E-K-N-S-A-Q-K-S-A-M-R-T-A-I-K-A-F-E-A-N-P-S-E-E-L-F-R-A-A-S-S-A-I-D-K-A-E-T-K-G-L-I-H-K-N-K-A-S-R-D-K-A-R-L-S-A-K-L-A-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-K-L-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-I-N-I-M-G-F-T-K-E-F-N-A-R-T-A-D-Q-A-G-M-I-I-P-V-V-I-S-V-Y-E-D-K-S-F-T-F-V-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-E-K-G-S-G-T-P-N-K-T-K-V-A-T-V-T-R-A-Q-V-Q-E-I-A-E-T-K-M-P-D-L-N-A-A-N-V-E-S-A-M-R-M-I-E-G-T-A-R-S-M-G-F-T-V-V-D"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-Q-D-I-K-N-E-E-V-E-E-V-Q-E-E-E-V-V-E-T-A-E-E-T-T-P-E-K-S-E-L-D-L-A-N-E-R-A-D-E-F-E-N-K-Y-L-R-A-H-A-E-M-Q-N-I-Q-R-R-A-N-E-E-R-Q-N-L-Q-R-Y-R-S-Q-D-L-A-K-A-I-L-P-S-L-D-N-L-E-R-A-L-A-V-E-G-L-T-D-D-V-K-K-G-L-A-M-V-Q-E-S-L-I-H-A-L-K-E-E-G-I-E-E-I-A-A-D-G-E-F-D-H-N-Y-H-M-A-I-Q-T-L-P-G-D-D-E-H-P-V-D-T-I-A-Q-V-F-Q-K-G-Y-K-L-H-D-R-I-L-R-P-A-M-V-V-V-Y-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-N-R-A-P-K-R-D-V-L-P-D-P-L-Y-N-S-Q-L-V-T-R-L-I-N-R-V-M-L-D-G-K-R-G-T-A-A-S-I-V-Y-G-A-F-E-Q-I-K-E-A-T-G-N-D-A-L-E-V-F-E-T-A-M-E-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-S-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-T-I-A-R-L-R-G-E-H-T-M-Q-D-R-L-A-K-E-I-L-D-A-A-N-N-T-G-A-A-V-K-K-R-E-D-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R-W"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-E-G-S-R-K-V-R-N-R-V-G-R-G-T-S-S-G-N-G-K-T-S-G-R-G-Q-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-L-P-K-R-G-F-T-N-I-N-A-K-E-Y-A-I-V-N-L-D-Q-L-N-V-F-E-D-G-A-E-V-T-P-V-V-L-I-E-A-G-I-V-K-A-E-K-S-G-I-K-I-L-G-N-G-E-L-T-K-K-L-T-V-K-A-A-K-F-S-K-S-A-E-E-A-I-T-A-K-G-G-S-V-E-V-I"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-L-R-Q-K-R-H-R-R-V-R-G-K-L-S-G-T-A-D-R-P-R-L-N-V-F-R-S-N-T-G-I-Y-A-Q-V-I-D-D-V-A-G-V-T-L-A-S-A-S-T-L-D-K-E-V-S-K-G-T-K-T-E-Q-A-V-A-V-G-K-L-V-A-E-R-A-N-A-K-G-I-S-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-N-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-V-I-V-L-P-A-G-V-E-L-A-N-N-D-N-V-V-T-V-K-G-P-K-G-E-L-T-R-E-F-S-K-D-I-E-I-R-V-E-G-T-E-V-T-L-H-R-P-N-D-S-K-E-M-K-T-I-H-G-T-T-R-A-L-L-N-N-M-V-V-G-V-S-E-G-F-K-K-E-L-E-M-R-G-V-G-Y-R-A-Q-L-Q-G-S-K-L-V-L-A-V-G-K-S-H-P-D-E-V-E-A-P-E-G-I-T-F-E-L-P-N-P-T-T-I-V-V-S-G-I-S-K-E-V-V-G-Q-T-A-A-Y-V-R-S-L-R-S-P-E-P-Y-K-G-K-G-I-R-Y-V-G-E-F-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-N-R-L-K-E-K-Y-L-N-E-V-V-P-A-L-T-E-Q-F-N-Y-S-S-V-M-A-V-P-K-V-D-K-I-V-L-N-M-G-V-G-E-A-V-S-N-A-K-S-L-E-K-A-A-E-E-L-A-L-I-S-G-Q-K-P-L-I-T-K-A-K-K-S-I-A-G-F-R-L-R-E-G-V-A-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-V-S-V-S-L-P-R-V-R-D-F-H-G-V-P-T-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-N-F-D-D-V-D-K-T-R-G-L-D-I-V-I-V-T-T-A-N-T-D-E-E-S-R-A-L-L-T-G-L-G-M-P-F-A-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-L-Y-D-V-I-K-K-P-V-I-T-E-S-S-M-A-Q-L-E-A-G-K-Y-V-F-E-V-D-T-R-A-H-K-L-L-I-K-Q-A-V-E-A-A-F-E-G-V-K-V-A-N-V-N-T-I-N-V-K-P-K-A-K-R-V-G-R-Y-T-G-F-T-N-K-T-K-K-A-I-I-T-L-T-A-D-S-K-A-I-E-L-F-A-A-E-A-E"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-D-Y-I-K-G-N-L-T-K-I-T-A-K-Y-I-V-L-E-T-G-G-L-G-Y-V-I-N-V-A-N-P-Y-S-F-S-N-Q-I-N-Q-A-I-Q-I-Y-I-H-H-V-V-R-E-D-A-H-L-L-Y-G-F-H-T-E-D-E-K-A-V-F-L-N-L-I-S-V-S-G-I-G-P-T-S-A-L-A-I-I-A-A-D-D-N-E-G-L-V-K-A-I-D-H-S-D-V-N-Y-L-M-K-F-P-K-I-G-K-K-T-A-Q-Q-M-V-L-D-L-A-G-K-F-V-D-I-N-E-V-S-T-D-K-S-K-V-S-T-I-N-N-N-Q-E-L-E-E-A-V-E-A-L-L-A-L-G-Y-K-T-N-E-L-K-K-I-E-K-F-F-E-G-T-T-D-T-A-E-N-Y-I-K-S-A-L-K-M-L-M-K"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-V-Q-L-K-E-E-K-E-Q-T-V-G-G-F-V-L-A-G-A-S-Q-E-K-T-K-K-A-Q-V-V-A-V-G-E-G-V-R-T-L-T-G-E-L-V-A-S-S-L-V-Q-G-D-T-I-L-I-E-N-H-V-G-T-P-V-K-D-D-G-K-D-C-L-I-I-R-E-A-D-V-L-A-V-V-N-D"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-L-N-R-V-V-L-V-G-R-L-T-R-D-P-D-L-R-Y-T-P-N-G-V-A-V-A-N-F-N-I-A-V-N-R-P-F-S-N-Q-Q-G-N-R-E-A-D-F-I-N-C-V-I-W-R-R-P-A-E-N-L-A-N-Y-M-K-K-G-S-M-V-G-V-D-G-R-I-Q-T-R-N-F-E-G-Q-D-G-K-T-V-Y-V-T-E-V-V-A-D-S-V-Q-F-L-E-T-K-G-S-Q-G-G-Q-D-S-S-G-G-Y-Q-Q-N-R-N-Q-N-Q-Y-Q-N-Q-N-Q-Y-A-S-N-Q-N-Q-D-Q-E-D-P-F-K-N-N-G-E-P-I-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-E-K-D-N-Q-T-T-S-E-P-E-N-E-Q-E-I-I-D-V-N-D-S-G-E-Q-P-E-E-N-E-T-E-Q-P-Q-E-E-A-V-E-N-D-E-I-A-K-L-Q-Q-E-K-D-E-T-Y-N-R-L-V-R-L-Q-A-E-F-D-N-Y-K-R-R-T-L-K-E-R-E-A-D-R-K-Y-K-S-Q-D-L-I-T-E-L-L-P-A-I-D-N-F-E-R-A-L-Q-V-E-V-T-E-E-N-K-S-I-I-D-G-I-M-M-V-Y-R-Q-L-Q-E-A-L-T-S-Q-G-V-E-P-I-K-T-E-G-E-V-F-D-P-N-L-H-H-A-V-M-Q-I-E-D-E-N-M-D-S-N-T-V-V-E-E-L-Q-K-G-Y-Q-L-K-D-R-V-I-R-P-A-M-V-K-V-N-K"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-S-K-L-Q-R-H-I-K-I-R-E-L-I-T-E-N-I-I-E-T-Q-D-E-L-V-D-S-L-K-A-L-D-F-N-V-T-Q-A-T-V-S-R-D-I-K-E-L-Q-L-V-K-V-P-T-T-T-G-Q-Y-K-Y-S-L-P-A-D-Q-R-F-N-P-L-Q-K-L-K-R-L-I-V-D-T-F-V-K-I-E-H-A-S-H-F-I-I-L-H-T-L-P-G-N-A-H-A-V-G-V-L-I-D-N-L-D-W-E-E-I-M-G-T-I-C-G-D-D-T-C-L-I-I-C-R-T-P-E-Q-A-E-M-I-K-N-R-F-I-E-M-L"} +{"text": "### FUNCTION Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c ### SEQUENCE -M-D-I-Q-Q-N-K-T-N-K-Q-K-K-K-R-N-R-F-I-F-R-S-S-I-L-L-I-L-V-A-A-V-V-F-A-I-V-S-N-M-K-D-D-N-K-I-Y-R-V-G-D-A-A-P-D-F-Q-L-K-Q-I-S-E-E-V-D-Q-S-T-V-Q-L-S-D-L-E-G-K-G-V-M-L-N-F-W-A-T-W-C-D-P-C-K-A-E-M-P-Y-M-Q-D-L-Y-A-E-Y-K-E-K-G-V-E-I-V-A-V-S-L-D-G-T-E-L-V-V-D-Q-F-I-D-E-Y-D-L-T-F-P-V-P-H-D-K-N-G-E-V-K-D-L-Y-K-I-G-P-M-P-T-T-Y-F-I-K-P-N-G-E-I-E-E-I-V-Q-G-A-L-T-L-D-R-L-E-G-Y-L-N-D-I-A-P-Q-Q-N"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-K-K-K-T-E-I-L-D-A-A-S-I-Q-R-A-L-T-R-M-S-H-E-I-L-E-K-N-K-G-G-E-N-L-V-L-I-G-I-K-T-R-G-V-P-L-A-K-R-I-Q-Q-K-I-K-Q-I-E-S-I-E-V-P-L-G-E-L-D-I-T-M-Y-R-D-D-L-D-K-V-S-E-Q-E-D-P-K-I-N-S-V-S-I-G-M-D-I-T-D-K-H-V-I-L-I-D-D-V-L-F-T-G-R-T-V-R-A-A-M-D-A-V-M-D-V-G-R-P-S-T-I-Q-L-G-S-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-D-R-E-I-V-V-V-Q-L-S-E-Q-D-Q-E-D-R-V-S-L-Y-E-K"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-I-K-P-L-G-D-R-V-V-I-E-L-V-E-Q-E-E-T-T-A-S-G-I-V-L-P-D-S-A-K-E-K-P-Q-E-G-K-V-V-A-V-G-S-G-R-V-E-N-G-E-K-I-A-L-E-V-S-E-G-D-R-I-I-F-S-K-F-A-G-T-E-V-K-Y-E-G-T-E-Y-L-I-L-R-E-N-D-I-L-A-I-I-G"} +{"text": "### FUNCTION Negative regulator of sigma-B activity Phosphorylates and inactivates its specific antagonist protein, RsbV Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme ### SEQUENCE -M-S-N-Y-D-Y-I-E-M-K-V-P-A-K-P-E-Y-V-G-V-A-R-L-T-L-S-G-V-A-N-R-M-G-F-S-Y-E-S-I-E-D-L-K-V-A-V-S-E-A-I-T-N-A-V-N-H-A-Y-N-D-N-E-S-G-E-I-N-I-G-F-G-I-Y-E-D-H-I-E-I-M-I-A-D-R-G-E-S-F-D-L-E-K-I-K-Q-E-T-G-P-Y-H-P-E-E-P-V-E-K-L-R-E-G-G-F-G-L-F-L-I-E-A-L-M-D-D-V-K-I-N-N-Q-Y-G-V-M-I-M-M-S-K-Y-I-A-E-E-E-V-D-M-D-D-D-Q-I-S-T-T-Q"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-V-G-L-G-N-P-G-R-K-F-K-K-T-R-H-N-I-G-F-F-V-I-D-E-L-L-Q-R-H-K-W-K-L-N-N-S-K-F-E-G-D-Y-S-I-E-H-F-D-G-E-K-V-I-L-L-Q-P-Q-T-Y-M-N-L-S-G-K-S-I-S-P-L-M-D-Y-F-D-I-D-V-D-D-V-I-V-V-Y-D-D-L-D-L-P-T-G-K-I-R-L-R-Q-K-G-G-H-G-G-H-N-G-V-R-S-T-I-D-H-L-G-T-K-D-F-K-R-V-R-L-G-I-G-R-P-T-N-A-T-P-V-I-D-Y-V-L-G-K-F-P-K-Q-E-T-T-A-V-T-D-S-V-E-K-A-A-D-A-I-E-A-W-I-K-G-K-P-F-L-E-V-M-N-D-F-N-Q"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-V-K-K-K-E-E-S-G-H-S-P-L-V-N-K-K-A-K-F-N-F-E-L-I-S-F-I-E-A-G-I-V-L-S-G-S-E-V-K-S-L-R-D-K-K-G-N-L-T-D-A-F-A-K-I-K-N-G-E-V-F-L-E-N-F-S-I-A-P-Y-K-N-G-G-Y-A-N-H-P-E-I-R-P-R-K-L-L-L-H-K-K-E-I-E-K-L-E-R-Q-V-K-E-K-G-L-V-L-V-A-T-K-V-Y-F-K-N-N-L-R-V-K-V-E-I-A-V-G-K-P-K-K-L-H-D-K-R-D-D-L-Q-K-K-D-A-Q-Q-E-I-A-R-A-L-K-S-S-N-R-Y-Q"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-N-V-N-I-K-P-L-E-D-K-I-L-V-Q-I-N-E-A-E-T-T-T-A-S-G-L-V-I-P-D-S-A-K-E-K-P-Q-E-A-T-V-I-A-V-G-P-G-R-F-D-E-K-G-E-R-I-P-L-D-I-K-E-D-D-V-V-I-F-S-R-Y-G-G-T-E-I-K-F-D-G-V-E-Y-L-L-L-S-A-R-D-I-L-A-I-V-E-K"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-T-V-G-L-F-G-G-S-F-N-P-P-H-G-G-H-A-L-V-A-E-I-A-I-R-R-L-K-L-D-Q-L-W-W-M-V-T-P-G-N-P-L-K-D-S-R-E-L-A-S-L-S-E-R-L-R-L-S-E-E-V-A-E-D-P-R-I-K-V-T-A-L-E-A-A-F-H-V-R-Y-T-A-D-T-L-A-L-I-R-N-A-N-P-D-V-Y-F-V-W-V-M-G-A-D-N-L-A-S-F-H-R-W-Q-R-W-R-E-I-A-Q-N-F-P-I-A-I-I-D-R-P-G-S-T-L-S-Y-L-S-S-R-M-A-Q-T-F-S-D-S-R-L-D-E-R-Y-A-P-V-L-A-R-R-M-P-P-A-W-T-F-I-H-G-P-R-S-S-L-S-S-T-A-L-R-K-V-Q-L-K-K-A-P-S-K-K"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-S-I-K-L-T-P-L-E-D-K-I-I-V-K-Q-A-E-A-Q-T-Q-T-A-S-G-L-Y-I-P-D-N-A-K-E-K-P-Q-Q-G-E-V-L-A-V-G-P-G-R-R-D-D-K-G-E-R-I-P-M-D-V-K-V-G-D-K-V-L-Y-S-K-Y-G-G-T-E-V-H-Y-E-G-E-D-Y-L-I-V-G-A-R-D-I-L-A-I-L-G"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-L-N-I-S-T-A-L-R-S-F-T-Q-R-Y-I-D-L-W-Q-Q-Q-T-G-H-L-P-A-S-K-E-L-Y-G-V-P-S-P-C-I-V-E-T-G-E-D-Q-V-F-W-Q-P-Q-A-F-L-P-E-A-T-L-T-N-I-E-R-A-L-E-I-Q-L-H-P-D-I-H-D-F-Y-T-Q-Q-Y-A-G-D-M-M-A-D-L-G-N-H-R-F-T-L-L-Q-V-W-S-E-D-D-F-I-R-L-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-L-F-L-A-T-T-S-S-E-M-T-M-A-S-L-C-N-V-S-G-N-V-V-L-E-Q-F-G-S-D-K-R-T-L-L-A-S-T-L-S-H-F-L-D-A-L-R-P-V-L-P-E"} +{"text": "### FUNCTION Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD As a transcriptional regulator, acts as an anti-FlhDC factor ### SEQUENCE -M-E-R-H-Q-H-L-L-S-E-Y-Q-Q-I-L-T-L-S-E-Q-M-L-M-L-A-T-V-E-N-W-N-A-L-V-D-L-E-M-T-Y-L-K-A-V-E-N-T-A-N-I-T-I-S-S-C-T-S-P-V-L-Q-E-L-L-R-Q-K-L-R-S-I-L-E-N-E-I-E-I-K-R-L-L-Q-R-R-L-D-K-L-S-E-L-V-G-Q-S-T-R-Q-Q-A-V-N-R-T-Y-G-Q-F-P-D-Q-A-L-L-L-G-E-T-Q"} +{"text": "### FUNCTION Guanidinium ion exporter Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons ### SEQUENCE -M-A-W-I-I-L-V-I-A-G-L-L-E-V-I-W-A-I-G-L-K-Y-S-H-G-F-S-R-L-T-P-S-I-I-T-L-V-A-M-A-A-S-V-F-L-L-A-Y-A-M-K-S-L-P-A-G-T-A-Y-A-V-W-T-G-I-G-A-V-G-T-A-I-L-G-I-V-L-L-G-E-S-A-S-L-A-R-I-L-S-L-G-L-I-L-A-G-I-I-G-L-K-L-A-S"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-P-Q-Y-N-K-L-Q-V-E-A-I-F-G-G-T-V-I-D-H-I-P-A-Q-V-G-L-K-L-L-S-L-F-K-W-L-H-T-K-E-R-I-T-M-G-L-N-L-P-S-N-Q-Q-K-K-K-D-L-I-K-L-E-N-V-L-L-N-E-D-Q-A-N-Q-L-S-I-Y-A-P-L-A-T-V-N-Q-I-K-N-Y-I-V-I-K-K-Q-K-L-K-L-P-K-I-I-N-G-I-L-S-C-P-N-E-N-C-I-S-K-V-E-L-K-A-A-D-F-I-V-K-I-K-L-N-K-I-Y-L-K-C-K-Y-C-E-R-D-F-D-H-K-I-V-T-K-I"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-T-R-I-A-G-V-N-I-P-E-K-K-H-I-V-I-A-L-K-K-I-Y-G-I-G-N-V-L-A-R-K-I-C-K-K-T-G-I-N-F-S-K-K-V-N-S-L-D-S-S-E-I-E-L-I-R-N-E-V-L-K-L-K-I-E-G-D-L-R-R-E-M-T-L-N-I-K-R-L-I-D-L-G-T-Y-R-G-L-R-H-K-K-H-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Y-L-N-T-I-S-P-M-K-K-S-N-H-S-S-K-R-K-G-R-G-I-G-S-G-K-G-K-T-S-G-R-G-H-K-G-Q-R-S-R-S-G-G-K-V-R-R-G-F-E-G-G-Q-M-P-L-Y-R-R-L-P-K-F-G-H-N-K-S-K-K-S-F-F-K-K-E-I-K-L-S-E-F-M-K-I-K-D-S-F-I-D-L-I-V-L-K-K-N-K-I-I-N-S-K-I-K-I-V-K-I-I-F-S-K-N-F-N-K-K-I-N-I-K-N-L-K-V-S-K-N-A-K-K-E-I-E-F-F-G-G-T-I-N"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-V-N-F-E-K-N-I-N-E-L-Q-E-K-L-I-S-V-N-R-V-S-K-T-V-K-G-G-R-I-F-S-F-T-A-L-T-V-V-G-D-C-Q-G-K-I-G-F-G-Y-G-K-S-K-E-V-P-L-A-I-Q-K-A-M-D-K-A-R-K-N-M-I-I-I-P-I-V-C-K-T-L-Q-H-E-I-N-G-Y-H-T-G-S-R-V-F-M-K-P-A-S-E-G-T-G-I-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-H-N-V-L-A-K-V-Y-G-S-T-N-P-I-N-V-V-R-A-T-V-N-A-L-K-K-M-R-F-P-M-H-I-A-E-K-R-G-K-S-I-D-D-I-L-G"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-K-K-K-L-S-R-I-I-R-A-T-R-T-R-K-R-I-R-S-L-E-I-E-R-L-V-V-Y-R-T-S-K-H-V-Y-A-Q-I-I-S-S-D-C-S-N-V-L-A-S-A-S-T-L-E-K-K-I-S-N-K-V-N-F-T-G-N-K-K-A-A-L-L-V-G-K-K-I-A-E-R-A-L-K-K-N-I-K-K-I-A-F-D-R-S-G-F-K-Y-H-G-R-I-K-E-L-A-E-S-A-R-K-F-G-L-N-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-S-D-M-I-T-R-I-R-N-G-Q-S-A-K-K-E-L-I-S-M-P-Y-S-N-L-K-K-S-I-A-N-L-L-K-E-E-G-F-I-L-D-Y-K-V-E-D-N-K-K-P-T-L-K-L-N-L-K-Y-F-K-N-N-P-V-I-E-K-I-K-R-I-S-R-P-G-L-R-I-Y-K-K-R-K-H-L-P-N-V-M-S-G-M-G-I-A-I-V-S-T-S-R-G-I-M-T-D-K-L-A-R-T-Y-N-L-G-G-E-I-I-C-Y-V-E"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-T-R-K-S-I-Q-E-R-E-K-K-R-I-K-L-A-K-T-F-L-K-K-R-K-E-L-K-K-I-I-S-D-P-N-I-G-N-D-I-R-W-N-A-V-L-K-L-Q-S-L-P-R-D-S-S-L-S-R-Q-R-N-R-C-S-Q-T-S-R-P-H-A-F-L-R-K-F-G-L-S-R-I-K-L-R-E-A-A-M-R-G-E-I-P-G-L-R-K-S-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-Q-L-Y-D-F-Y-K-K-N-V-L-I-K-L-K-N-K-F-N-Y-K-S-I-M-Q-V-P-K-I-E-K-I-T-L-N-M-G-V-G-K-A-S-F-D-K-K-L-L-E-H-A-V-N-D-L-T-L-I-S-G-Q-K-P-Y-I-T-K-A-K-K-S-I-A-N-F-K-I-R-Q-G-H-P-I-G-C-K-V-T-L-R-G-K-L-M-W-F-F-F-Q-K-L-I-C-I-A-I-P-R-I-R-D-F-R-G-L-P-V-K-S-F-D-G-F-G-N-Y-S-L-G-I-K-E-Q-I-I-F-P-E-I-D-Y-D-K-I-D-K-I-R-G-L-D-I-T-I-T-T-N-A-K-S-D-K-E-G-L-A-L-L-S-A-F-N-F-P-F-R-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-K-K-I-K-L-N-D-E-I-I-V-R-V-G-K-Y-K-G-K-T-G-K-I-K-K-I-F-S-D-G-K-A-I-I-E-G-I-N-I-S-K-K-H-K-K-P-T-P-N-E-K-Q-S-G-G-I-F-E-K-E-Q-P-I-S-L-S-N-V-A-I-F-N-I-D-T-N-K-P-D-K-V-K-F-K-I-E-K-G-K-K-Y-R-I-F-K-S-N-G-K-K-I-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-V-Q-T-I-L-S-V-A-D-N-S-G-A-R-L-V-M-C-I-K-V-L-G-G-S-R-R-R-Y-A-K-I-S-D-I-I-K-I-A-V-K-E-A-I-P-R-A-K-V-K-K-G-E-V-L-K-A-V-I-V-R-T-K-K-N-L-H-R-S-D-G-S-V-L-R-F-D-K-N-A-C-V-L-L-N-D-S-T-E-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-K-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-K-K-K-K-V-E-I-I-M-G-K-K-K-L-Q-I-L-K-G-S-V-I-K-N-K-M-Q-K-S-I-V-V-S-V-E-R-F-V-K-H-P-I-Y-K-K-F-M-K-K-T-T-K-L-H-V-H-D-E-N-N-S-S-K-V-G-D-V-V-E-I-Q-E-C-R-P-I-S-K-T-K-S-W-K-L-I-N-I-K-K-N-N"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-M-Q-K-G-R-N-R-G-L-S-V-N-S-E-I-N-F-G-K-F-G-L-K-A-I-Q-R-G-R-L-T-S-R-Q-I-E-S-A-R-R-A-M-S-R-S-I-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-K-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-I-L-Y-E-I-D-E-V-S-E-T-I-A-R-Y-A-F-K-L-A-T-A-K-L-P-I-T-T-T-F-V-N-K-M-V-M"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-V-A-H-H-R-Y-A-K-S-S-S-Q-K-V-R-L-V-A-D-L-I-R-G-C-D-A-S-R-A-M-E-I-L-N-F-S-N-K-K-A-A-R-L-I-K-K-I-L-K-S-A-I-S-N-A-E-H-N-E-G-E-N-I-E-N-L-K-I-K-T-I-Y-V-N-P-G-P-S-I-K-R-I-M-P-R-A-K-G-R-S-D-R-I-L-K-R-T-S-H-I-T-I-V-L-S-G-K-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-F-H-L-L-K-K-I-E-E-I-K-Q-T-G-K-K-K-L-I-R-T-W-S-R-R-S-T-I-F-P-D-M-I-G-M-T-I-S-V-H-N-G-K-Q-H-I-P-I-F-I-G-D-E-M-V-G-H-K-L-G-E-F-V-P-T-R-T-Y-R-G-H-S-A-D-K-K-I-K-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-N-K-K-E-N-I-F-K-I-L-T-S-S-Y-S-S-E-K-S-S-I-L-S-E-K-N-N-T-F-T-F-K-V-L-K-N-S-K-K-S-E-I-K-S-S-I-E-K-F-F-N-V-K-V-K-K-V-R-T-V-M-L-K-G-K-S-K-K-H-K-N-I-I-G-K-R-K-N-W-K-K-A-Y-V-V-L-K-K-N-Q-K-I-N-L-I-K-N-I-E"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-R-I-R-I-R-L-K-A-F-D-H-R-L-I-D-Q-S-T-S-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-K-F-T-I-L-V-S-P-H-V-D-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-L-V-D-I-V-K-P-T-E-K-T-V-D-A-L-M-R-L-D-L-A-S-G-V-D-V-Q-I-S-L-G"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-N-K-L-M-K-Q-A-Q-K-I-Q-E-K-M-K-L-I-Q-E-E-I-S-K-L-E-A-I-G-E-S-G-A-G-L-V-K-I-K-L-N-G-S-R-Y-C-N-Y-V-K-I-D-N-S-L-L-K-D-K-E-M-L-E-D-L-I-V-A-A-F-N-D-A-I-R-R-I-S-E-I-Q-Q-E-K-I-A-S-V-S-S-S-I-Q-I-P-E-G-F-K-M-P-F"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-I-N-K-Q-Q-I-L-D-A-V-S-E-M-S-V-L-E-I-S-E-L-V-S-M-M-E-K-K-F-G-V-S-S-I-N-N-N-N-I-N-V-N-K-V-D-E-S-V-E-E-K-S-E-F-D-V-L-L-L-E-I-G-K-N-K-I-S-V-I-K-S-V-R-S-A-L-S-L-G-L-K-E-S-K-D-L-I-E-S-E-L-P-I-T-L-K-T-G-L-N-K-K-D-A-E-S-L-K-K-E-I-E-T-S-G-A-R-I-E-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-L-N-R-K-N-K-E-N-I-I-S-K-I-N-K-I-T-K-S-S-L-S-I-L-I-V-D-P-T-G-I-T-S-N-Q-M-N-N-L-R-K-S-S-R-K-L-N-V-N-I-K-Q-V-R-N-T-L-M-R-F-A-I-V-D-T-E-F-D-C-L-E-K-Y-I-K-G-S-N-L-I-A-F-S-H-S-H-P-G-S-A-A-R-I-F-K-N-F-T-K-E-N-N-K-I-K-I-K-L-A-V-F-E-R-K-I-I-T-D-S-N-I-D-Y-L-A-N-L-P-T-H-E-E-S-V-I-N-F-I-N-I-I-Q-E-A-S-I-K-K-L-I-R-I-L-I-L-I-N-N-N-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-T-K-K-I-K-A-Y-V-K-L-Q-I-K-A-G-S-A-N-P-S-P-P-I-G-P-A-L-G-Q-Q-G-V-N-I-I-E-F-C-K-S-F-N-A-K-T-N-K-I-D-K-D-T-P-I-P-V-I-I-S-V-Y-N-D-R-T-F-S-F-I-T-K-T-P-P-T-A-F-F-L-K-Q-A-A-N-I-K-S-G-S-D-N-P-K-N-K-K-I-G-K-I-S-I-F-K-I-N-E-I-A-K-K-K-S-P-D-M-T-G-S-T-L-N-S-I-S-K-S-I-I-G-T-A-K-S-M-G-L-S-I-E-D"} +{"text": "### FUNCTION Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress ### SEQUENCE -M-I-S-S-K-F-G-I-G-Q-Q-V-R-H-K-L-L-G-Y-L-G-V-I-I-D-V-D-P-E-Y-S-L-E-K-P-S-L-E-E-I-S-A-D-D-S-L-R-R-S-P-W-Y-Y-V-V-M-E-D-E-D-G-K-P-V-H-T-Y-L-A-E-A-Q-L-G-Y-E-I-S-P-V-H-P-E-Q-P-K-L-D-E-L-S-A-S-I-K-K-Q-L-K-T-P-R-L-R-N"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-T-S-R-G-I-N-K-V-I-L-I-G-N-L-G-Q-D-P-E-V-R-Y-I-P-N-G-N-A-I-T-N-L-S-L-A-T-S-E-N-W-R-D-K-N-T-G-E-S-K-E-K-T-E-W-H-R-V-I-L-F-G-K-L-A-E-V-A-G-E-Y-L-K-K-G-S-Q-V-Y-I-E-G-N-L-Q-T-R-K-W-Q-D-Q-N-G-Q-D-R-Y-I-T-E-I-V-V-G-I-N-G-C-M-Q-M-L-G-N-R-A-S-Y-D-Y-T-K-P-E-A-K-E-W-N-K-K-N-K-N-I-I-N-E-K-Q-D-I-K-E-S-K-K-N-K-I-E-E-E-I-N-F-D-D-D-I-P-F"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-V-L-S-I-L-N-Y-P-N-K-K-L-R-K-I-A-S-N-I-S-L-I-D-S-E-I-K-S-L-I-K-N-M-L-E-T-M-Y-F-N-E-G-I-G-L-A-A-T-Q-V-D-V-H-K-R-I-I-V-I-D-I-S-K-N-K-N-K-P-L-I-L-I-N-P-V-F-I-N-K-C-G-A-Q-T-F-E-E-G-C-L-S-I-P-K-K-T-A-F-V-N-R-S-K-K-V-K-I-K-A-I-N-C-L-G-E-E-F-L-L-K-S-K-G-L-L-A-T-C-I-Q-H-E-M-D-H-L-I-G-K-L-F-I-D-Y-I-K-P-L-K-N"} +{"text": "### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate forming two phosphate ions ### SEQUENCE -M-N-L-N-S-V-P-A-G-E-K-L-P-N-D-I-Y-A-I-I-E-I-P-T-N-S-N-P-I-K-Y-E-V-D-K-K-T-G-I-L-F-V-N-R-F-I-P-T-S-M-F-Y-P-C-N-Y-G-Y-I-N-H-T-I-S-L-D-G-D-P-L-D-I-L-V-P-T-P-Y-P-V-L-H-G-S-V-I-R-C-N-P-I-G-V-L-K-M-I-D-E-S-G-E-D-A-K-I-I-A-M-P-H-Q-K-L-L-A-G-Y-N-N-N-I-K-N-I-D-D-I-S-N-L-M-K-S-Q-I-S-H-F-F-E-H-Y-K-D-L-E-K-K-K-W-T-K-V-I-S-W-E-D-V-K-S-A-E-K-E-I-L-S-S-F-N-R-K-K-T-L-N-I"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-F-K-I-N-G-V-Q-Y-K-A-K-S-G-S-V-V-C-L-N-K-I-S-G-D-I-G-S-T-I-E-I-K-K-I-M-A-L-F-N-D-E-K-I-I-F-G-Q-P-F-I-K-N-S-R-I-I-A-T-I-K-K-H-I-N-G-K-K-I-S-I-V-K-F-S-R-R-K-H-F-K-K-I-T-G-Y-R-Q-K-L-T-N-I-K-I-I-D-I-C-C"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-N-D-N-F-L-N-I-Q-I-E-C-C-L-Y-K-Q-T-P-S-I-D-K-F-K-F-W-I-K-S-I-F-L-H-F-K-K-V-S-E-I-N-L-R-L-V-E-K-K-E-I-K-N-L-N-K-K-F-L-K-K-N-Y-P-T-N-I-L-A-F-P-C-I-M-P-N-N-D-Q-I-S-F-L-G-D-L-V-V-C-S-E-I-V-E-K-E-A-K-N-Q-N-K-S-V-E-S-H-W-A-H-I-I-I-H-G-T-L-H-L-L-G-Y-D-H-S-N-N-S-N-K-I-E-E-M-E-I-L-E-I-K-F-L-N-L-F-G-Y-H-N-P-Y-F"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-N-H-T-P-I-L-N-K-K-N-L-I-W-I-D-L-E-M-T-G-L-N-L-E-N-D-R-I-I-E-I-A-T-V-I-T-D-K-Y-V-K-I-L-A-E-G-P-S-I-A-I-F-Q-S-E-E-Q-L-K-K-M-N-S-W-N-I-F-T-H-T-K-N-G-L-I-D-R-V-R-K-S-K-Y-N-E-K-N-A-M-I-D-T-L-K-F-I-S-S-W-V-P-F-G-K-S-P-I-C-G-S-S-I-N-H-D-R-L-F-L-S-K-Y-M-P-D-L-E-K-Y-F-H-Y-R-C-L-D-V-S-V-I-K-E-L-A-R-R-W-K-P-K-I-L-S-K-L-K-K-K-H-T-H-K-A-L-D-D-I-K-D-S-I-K-E-L-L-F-Y-K-D-T-F-I-K-L-N"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-V-Q-D-A-V-E-K-I-G-N-R-F-D-L-V-L-V-A-S-Q-R-A-R-E-M-Q-I-F-G-K-S-P-M-V-D-K-E-N-D-K-Y-T-V-I-A-L-R-E-I-E-Q-G-L-I-E-K-Q"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-K-K-V-N-I-R-I-L-D-K-R-F-G-K-E-F-F-L-P-K-Y-F-T-D-G-S-S-G-M-D-L-R-A-C-I-D-K-E-I-N-L-N-P-N-E-T-V-L-I-S-T-G-V-S-I-D-I-S-D-Q-K-I-S-G-L-I-L-P-R-S-G-L-S-H-K-Y-G-I-I-L-S-N-T-I-G-L-I-D-S-D-Y-Q-G-P-I-M-I-S-M-L-N-R-S-N-K-N-F-L-I-S-I-G-D-R-I-A-Q-I-I-F-V-P-L-I-Q-I-E-W-N-I-V-N-K-F-V-K-I-T-N-R-K-D-M-G-F-G-H-S-G-K-N"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-E-I-Y-E-N-S-N-S-R-M-K-K-S-I-D-F-F-K-K-N-I-S-K-I-R-T-N-R-V-S-P-S-L-I-E-N-I-Y-I-N-C-Y-G-T-S-V-P-L-S-K-L-S-N-I-L-S-E-K-S-N-I-L-K-I-N-V-F-D-N-N-I-I-K-K-I-E-Q-A-I-L-S-S-D-L-G-V-N-P-Q-I-Q-E-N-Y-I-R-I-E-F-P-K-L-T-E-A-R-R-F-E-L-I-K-L-I-N-K-E-A-E-Q-N-I-I-S-I-R-N-I-R-R-D-A-N-E-K-I-K-K-L-I-K-A-K-T-I-G-K-D-E-D-K-K-F-Q-E-V-I-Q-N-L-T-N-S-R-I-E-D-T-K-K-I-L-K-L-K-E-K-E-I-K-K-I"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-A-L-L-K-F-F-I-S-K-K-E-I-T-S-D-I-A-K-E-R-L-Q-I-I-V-S-E-Q-R-K-N-S-K-E-P-N-Y-L-P-M-L-K-K-D-L-I-K-V-I-K-K-Y-I-N-L-N-S-E-T-L-C-V-K-L-D-H-K-N-K-K-N-I-K-I-F-E-L-N-I-V-F-P-E-K-N-F-L-N-K-K"} +{"text": "### FUNCTION Participates in cysteine desulfuration mediated by SufS Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process ### SEQUENCE -M-N-K-F-I-K-K-I-N-F-I-K-N-F-S-S-C-E-N-W-E-E-K-Y-L-Y-I-I-E-L-G-N-K-L-S-P-F-P-E-K-F-R-K-N-S-N-L-I-P-G-C-Q-N-D-S-W-I-Y-L-I-Y-E-N-T-K-K-I-K-F-Y-G-D-S-N-S-L-I-V-K-G-L-I-A-I-I-F-I-L-H-E-D-L-K-L-S-E-I-L-T-F-D-V-K-P-Y-F-N-K-L-S-L-T-N-Y-L-T-P-S-R-V-Q-G-L-S-S-I-S-K-F-I-K-K-S-A-R-C-L-L-I-K-E-K-I-L"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-K-L-I-V-G-L-S-N-P-I-N-L-Y-Y-N-T-R-H-N-I-G-S-W-Y-I-K-F-L-A-K-K-Y-K-K-N-L-I-K-N-K-K-Y-C-F-Y-Y-I-D-V-K-I-G-D-Y-Y-S-K-L-V-I-P-D-T-Y-M-N-V-N-G-T-I-I-Y-N-I-T-N-F-Y-K-I-Y-S-N-E-M-L-I-V-H-D-D-L-D-L-D-T-G-I-A-R-F-K-F-N-H-K-N-S-T-H-N-G-I-K-S-I-Y-K-S-F-G-A-K-C-I-F-N-T-L-R-I-G-I-G-R-P-K-L-N-K-N-I-N-S-Y-L-L-N-N-P-S-P-K-E-E-I-L-I-K-K-T-I-T-K-C-I-K-C-T-D-V-L-I-K-K-N-K-D-H-A-M-N-I-L-H-K-K"} +{"text": "### FUNCTION Transcription regulator that can specifically activate or repress expression of target genes ### SEQUENCE -M-E-S-P-L-G-S-D-L-S-R-L-V-R-I-W-R-A-L-I-D-H-R-L-K-P-L-E-L-T-Q-T-H-W-I-T-L-H-N-I-C-Q-L-P-P-E-Q-S-Q-I-Q-L-A-K-A-I-G-I-E-Q-P-S-L-V-R-T-L-D-Q-L-E-E-K-G-L-I-T-R-H-T-C-S-N-D-R-R-A-K-R-I-K-L-T-K-S-A-E-P-I-I-Q-K-V-N-N-V-I-H-T-T-R-E-E-I-L-N-G-I-N-Q-E-E-I-Q-W-L-S-Q-M-I-S-K-L-E-K-N-I-L-E-L-Y-N-K-S"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-I-I-S-K-S-A-K-H-Y-L-S-K-L-L-S-K-K-K-K-G-T-N-I-K-L-S-I-E-N-K-D-K-E-N-L-T-C-Q-I-K-Y-F-D-K-K-E-E-N-F-N-Y-T-K-F-N-F-I-D-F-K-V-Y-V-K-K-N-I-F-I-Y-I-K-K-I-K-I-D-I-E-S-K-S-L-K-D-E-I-I-I-K-I-F-K-K-R-E-N-L-K-N-R-I-S-N-F-I-K-Y-K-I-N-S-K-L-E-Y-H-G-G-F-V-E-L-I-D-I-K-E-N-M-F-V-I-L-K-F-F-G-G-C-N-G-C-S-M-A-K-V-T-L-K-E-G-I-E-K-E-I-K-K-N-F-P-N-I-K-G-V-I-D-I-T-D-H-I-H-S-E-S-S-F-Y"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-S-K-K-R-S-I-Q-S-E-K-K-R-K-Y-N-S-S-K-K-S-M-I-R-S-F-I-K-K-V-K-N-S-I-L-K-K-E-K-D-T-I-N-N-S-F-I-E-M-Q-S-I-L-D-R-Y-A-K-K-N-L-I-H-K-N-K-A-S-R-L-K-S-R-L-S-K-K-I-K-F-I-F-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-35 is required for alleviation ### SEQUENCE -M-I-I-Y-Y-S-A-N-Q-S-K-S-G-L-K-I-L-L-K-N-E-P-C-L-I-L-E-N-Q-F-V-K-P-G-K-G-Q-P-F-N-R-I-K-I-K-K-L-I-S-G-K-I-F-T-K-I-F-K-S-N-E-K-L-I-Y-A-D-V-L-D-V-K-V-K-S-L-Y-K-D-K-K-Y-W-N-F-I-K-K-E-N-F-E-Q-F-K-I-S-K-K-N-L-G-E-K-Y-K-W-I-I-E-Q-L-E-C-I-V-T-F-W-D-E-N-P-I-N-I-T-L-P-R-F-V-D-I-K-V-C-N-A-N-F-D-I-K-G-D-T-I-K-S-G-N-K-Y-I-I-L-T-T-G-A-I-I-K-A-P-I-F-I-R-S-E-E-I-V-R-V-D-T-N-L-G-E-Y-V-S-R-I-K"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-K-I-H-P-M-S-L-D-I-L-A-T-C-S-C-G-N-S-L-K-I-K-S-T-I-K-K-D-I-L-L-D-V-C-N-K-C-H-P-F-Y-T-G-T-Q-K-K-L-N-I-G-G-R-V-S-K-F-K-K-R-F-D-N-I-V-Y-K-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-L-M-I-H-T-D-Q-S-D-Q-I-S-N-I-I-E-H-Y-T-K-M-I-K-I-N-K-G-S-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-K-K-L-N-K-A-H-Y-I-L-M-N-I-E-T-S-T-K-V-L-N-N-I-I-Q-D-L-N-L-N-N-F-I-I-R-N-M-I-M-R-V-K-N-A-I-N-E-P-S-P-M-K-K-T-K-E-N-K-E-L-N-N"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-I-R-N-F-R-R-R-K-F-C-R-F-T-L-E-K-I-N-N-I-D-Y-K-D-I-I-L-L-K-N-Y-I-T-E-N-G-K-I-V-P-S-R-I-T-G-T-R-A-R-Y-Q-R-Q-L-S-R-A-V-K-R-A-R-Y-L-S-L-L-P-Y-T-D-H-H-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-K-K-I-I-N-K-G-N-I-G-D-K-I-K-V-K-A-G-Y-A-R-N-F-L-F-P-K-K-I-A-I-I-A-S-E-K-N-L-K-F-F-E-K-K-R-K-I-L-E-E-Q-S-K-Y-E-N-F-K-L-K-E-R-F-R-N-I-K-S-L-K-E-I-E-I-Y-C-K-A-G-S-K-G-K-L-F-G-S-I-G-A-N-H-I-I-E-K-I-K-E-R-G-I-R-I-M-K-N-E-I-K-L-T-N-G-P-L-K-T-I-G-K-H-N-I-K-I-K-V-K-S-N-M-C-T-E-I-C-V-I-L-K-N-N-I"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-L-I-N-I-I-E-N-S-Q-K-K-S-N-I-T-K-L-F-S-G-D-I-V-K-I-N-I-W-V-L-E-G-N-K-K-R-I-Q-I-F-E-G-I-I-I-A-I-K-N-K-G-I-S-S-S-I-T-V-R-K-I-S-N-G-E-G-V-E-R-M-F-P-L-H-S-P-I-I-E-S-I-I-V-N-R-H-S-L-V-R-K-S-K-L-Y-Y-L-R-N-K-K-G-R-S-S-R-I-K-Q-R-L-K-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-T-K-E-E-N-I-E-M-Q-G-I-V-L-D-T-L-P-N-T-M-F-K-V-E-L-E-N-K-H-V-V-L-A-H-I-S-G-K-M-R-K-N-Y-I-R-I-L-T-G-D-K-V-T-V-E-L-T-P-Y-D-L-S-K-G-R-I-I-F-R-S-R"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-N-Y-I-P-M-T-L-K-G-A-E-K-L-R-E-E-L-K-Y-L-K-Q-T-K-R-S-E-I-I-K-S-I-S-E-A-R-Q-Y-G-D-L-K-E-N-A-E-Y-Q-A-A-K-E-Q-Q-Y-F-C-E-S-R-I-K-E-I-E-S-K-L-M-H-S-K-I-I-D-I-K-K-I-P-F-R-D-R-V-V-F-G-S-T-I-T-I-K-N-L-K-T-L-E-E-K-T-Y-K-I-V-G-D-D-E-A-N-F-K-N-N-L-I-S-I-S-S-P-L-S-R-G-L-I-G-K-K-T-L-E-I-V-N-I-N-T-P-S-G-I-I-K-Y-K-I-L-K-I-N-Y-L"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-H-S-R-E-N-N-R-K-F-K-I-S-K-E-I-Q-R-K-I-A-L-I-L-Q-Q-K-I-N-D-P-R-I-G-I-S-T-V-S-G-V-D-L-S-S-D-F-S-H-A-K-I-F-V-T-F-L-N-K-N-T-K-Q-Q-I-K-S-G-L-F-I-L-N-K-A-S-F-F-I-R-K-I-L-N-K-T-M-R-L-R-I-I-P-K-L-T-F-I-Y-D-Y-S-L-I-K-G-R-N-I-D-D-L-F-N-N-N-I-V-K-I-S-K-K-S-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-Q-N-L-K-K-K-N-K-S-Y-K-E-T-L-H-T-L-N-I-K-E-D-S-E-K-Q-I-T-L-L-T-E-K-I-K-S-L-Q-K-H-F-L-E-N-K-N-D-L-H-S-R-R-G-L-L-K-K-V-S-R-R-R-K-I-L-N-Y-L-K-R-K-N-K-M-R-Y-F-D-L-I-K-K-L-N-L-R-N"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-I-G-I-G-I-D-I-V-N-L-E-R-I-N-K-I-I-L-C-Y-G-N-K-F-V-K-K-I-L-S-F-N-E-K-K-K-Y-Y-E-L-K-N-K-K-K-N-I-S-V-N-F-L-A-K-R-L-A-A-K-E-A-A-S-K-A-F-G-L-G-M-K-K-G-L-Y-F-S-Q-F-E-V-L-N-N-N-L-G-K-P-Y-F-K-F-N-N-T-A-K-N-L-I-K-A-L-N-I-T-N-I-H-L-S-L-T-D-E-R-K-Y-A-C-A-T-V-I-F-E-D-N-R-T-N-I-I-L-S"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-N-F-G-N-K-I-K-C-S-I-C-K-K-K-I-F-L-R-E-K-N-L-F-F-P-F-C-S-K-K-C-K-I-I-D-L-Y-Q-W-I-S-G-K-Y-K-L-F"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-T-L-R-R-E-R-I-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Y-I-E-S-F-D-Q-F-V-I-L-L-K-N-S-I-S-Q-M-I-Y-K-H-A-I-S-T-V-V-P-N-H-T-N-N-Q-E-H-N-Q-S-Q-Y-N-N-N-N-A-C-I-S-K-P"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-M-Y-R-N-N-L-L-I-S-F-D-F-G-T-K-N-I-G-V-A-I-G-Q-M-K-T-N-T-S-K-P-L-E-S-V-S-Y-V-K-G-V-P-N-W-G-K-I-N-N-I-I-L-L-W-E-P-K-Y-I-I-V-G-L-P-L-N-M-D-G-S-Y-Q-T-S-T-I-K-A-K-K-F-A-K-Q-L-R-N-K-F-F-M-P-V-M-M-H-D-E-R-L-T-T-I-E-A-K-S-V-L-F-K-K-Y-G-Y-K-G-L-K-K-K-L-I-D-S-E-S-A-V-I-I-L-D-S-W-M-N-S-I-Y-F-K-K"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-L-I-P-T-V-V-E-K-N-A-R-G-E-R-S-Y-D-I-F-S-R-L-L-K-E-R-I-I-F-V-T-G-K-I-E-D-Y-M-A-N-L-I-I-A-Q-M-I-F-L-E-S-E-D-P-E-K-D-I-F-L-Y-I-N-S-P-G-G-V-V-T-S-G-M-S-I-Y-D-T-M-Q-F-I-K-C-E-V-S-T-L-C-I-G-Q-S-S-S-M-A-A-L-I-L-A-S-G-E-K-G-K-R-F-S-L-P-N-A-R-I-M-I-H-Q-P-L-G-G-S-Q-G-Q-A-T-D-I-A-I-H-T-T-E-I-L-K-I-K-K-C-M-I-E-L-L-S-K-H-T-G-Q-S-A-E-I-I-S-K-D-T-E-R-D-R-F-F-S-G-S-E-A-V-I-Y-G-L-I-D-K-V-I-T-C-R-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-M-L-K-K-N-I-A-R-Q-N-W-H-I-F-D-A-K-N-K-I-L-G-R-F-S-T-K-L-A-S-I-L-K-G-K-N-D-I-T-Y-T-P-H-V-D-S-G-N-Y-V-I-V-I-N-S-K-K-I-K-I-T-G-K-K-L-K-N-K-F-Y-Y-H-H-T-G-Y-S-G-G-I-K-K-I-S-L-E-N-M-I-K-N-N-S-E-L-V-I-Y-K-S-V-K-G-M-L-P-K-G-S-L-G-R-V-M-I-K-K-L-K-I-F-S-G-E-S-H-N-H-E-A-Q-K-P-K-K-L-L-T"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-T-I-E-E-S-V-K-S-I-I-A-E-Q-L-G-V-K-K-E-E-V-T-N-N-A-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-A-A-I-D-F-I-K-E-S-K-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-I-K-R-G-V-S-S-K-F-R-H-K-K-I-L-K-K-T-K-G-Y-Y-G-A-R-S-R-S-Y-R-I-A-F-Q-A-F-I-K-A-G-Q-Y-A-Y-R-D-R-K-N-K-K-R-T-F-R-K-I-W-I-C-R-I-N-S-A-V-R-K-H-G-L-S-Y-S-C-F-M-Y-K-I-K-K-L-S-I-F-I-D-R-K-I-L-S-D-L-A-V-L-N-K-E-A-F-S-E-L-I-K-K-V-K-S-I-S"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-L-Y-T-K-K-L-N-K-K-K-L-N-T-K-E-I-N-I-K-T-G-K-K-F-Y-S-I-R-L-H-K-I-N-E-E-I-K-A-K-T-V-R-L-T-G-I-N-G-V-Q-L-G-I-V-P-I-K-E-A-I-F-K-S-L-E-L-E-M-D-L-V-E-I-S-P-N-S-N-P-P-V-C-K-I-M-N-Y-G-K-F-L-Y-E-K-N-K-S-N-K-E-Q-K-R-K-Q-K-I-I-N-T-K-E-I-K-F-R-P-N-T-D-T-G-D-Y-K-V-K-L-R-N-L-T-R-F-L-E-N-G-K-K-V-K-I-S-L-R-F-R-G-R-E-M-V-H-K-K-I-G-I-N-M-L-N-R-I-C-S-D-L-K-E-I-S-S-I-E-S-F-P-N-K-I-E-G-R-Q-M-T-L-I-L-V-P-K-K"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-E-N-N-K-L-F-N-L-K-L-T-D-L-A-K-N-K-I-K-N-L-L-K-E-E-K-N-K-N-K-K-F-R-I-Y-I-S-G-G-G-C-N-G-F-Q-Y-N-F-I-L-D-E-K-I-N-K-E-D-H-L-I-L-F-L-D-V-E-I-V-I-D-S-I-S-L-Q-Y-L-I-G-G-V-V-D-Y-K-E-E-L-L-E-S-C-F-F-V-I-N-P-N-A-K-T-T-C-S-C-G-T-S-F-S-I"} +{"text": "### FUNCTION Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-S-N-D-N-I-L-K-N-I-H-E-I-N-L-S-Y-L-L-L-A-Q-E-L-I-K-Q-D-K-K-V-A-S-F-R-L-G-V-C-E-D-T-L-N-K-I-S-K-L-S-L-S-E-L-I-K-L-G-A-I-N-Q-L-I-C-L-L-R-L-D-D-E-K-V-I-N-C-L-T-R-E-S-R-V-D-E-L-Q-Q-V-H-T-G-I-M-L-S-T-Q-L-L-R-S-H-K-S-N-S-N-H-A-L-K-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-K-M-V-N-Q-R-A-I-L-P-D-P-K-W-N-S-E-I-L-S-K-F-I-N-I-L-M-V-N-G-K-K-S-I-S-E-K-I-I-Y-T-A-L-N-N-L-K-K-K-L-N-K-D-H-L-T-I-F-D-L-A-L-E-K-V-R-P-I-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-I-E-V-R-S-S-R-R-N-A-L-A-M-R-W-I-I-E-A-A-R-K-R-K-D-K-S-M-S-L-R-L-A-K-E-I-E-D-A-L-E-N-K-G-T-A-V-K-K-R-E-E-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-V-T-I-N-Q-L-V-R-K-S-R-S-N-K-I-I-K-T-N-V-P-A-L-S-S-C-P-Q-K-R-G-V-C-I-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-T-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-S-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-C-A-G-V-K-N-R-K-K-A-R-S-K-Y-G-V-K-K-I-K-N-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-N-N-K-F-Y-Q-L-T-V-I-S-A-E-N-F-I-F-S-N-L-V-K-K-S-N-I-T-G-S-E-G-N-L-G-I-L-P-G-H-A-P-L-I-T-K-I-K-P-G-L-I-H-I-I-S-S-K-N-I-E-E-Y-I-Y-L-S-G-G-I-L-E-I-N-S-N-V-V-T-V-L-A-D-T-A-I-R-G-K-E-I-D-E-K-K-A-I-E-S-K-K-N-A-E-E-L-I-L-K-S-K-E-R-H-E-Y-I-R-A-V-I-E-L-S-K-A-I-A-K-L-R-V-C-K-L-S-N-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-T-I-Y-E-I-K-S-Y-L-S-R-P-Y-A-E-A-A-F-K-F-A-N-E-N-N-I-V-D-D-W-I-Y-M-I-E-E-I-C-K-I-L-K-N-I-K-I-Y-S-L-S-S-F-I-L-K-K-N-K-N-F-L-F-E-S-I-K-N-N-F-D-V-Y-F-N-N-F-V-K-I-I-I-E-N-N-R-L-I-I-F-P-E-I-L-N-Q-F-I-N-L-K-N-D-Q-N-N-I-E-N-I-T-I-I-S-K-Y-K-L-D-K-K-I-L-N-K-I-E-K-K-I-K-S-L-I-F-K-E-I-K-I-N-I-K-I-D-K-S-I-I-G-G-Y-I-I-K-S-K-N-F-L-I-D-N-S-I-K-N-K-L-Y-R-F-S-E-Y-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-I-N-A-T-I-F-G-Q-T-I-A-F-F-L-F-V-F-F-C-M-K-Y-I-W-P-N-L-I-S-L-V-E-K-R-R-E-N-I-A-Q-A-L-N-E-A-K-Q-A-K-L-N-L-K-I-S-K-E-K-A-K-K-R-I-E-S-A-Q-I-K-C-K-N-I-I-N-E-A-N-E-T-K-K-L-L-I-E-E-A-K-K-E-A-I-K-I-K-E-H-I-I-S-Q-G-R-L-D-I-L-D-E-K-K-R-M-C-E-D-L-K-T-K-I-S-E-I-I-V-M-S-V-E-K-I-I-E-S-S-I-N-K-K-I-S-D-N-I-I-E-R-S-I-S-K-I-N-K-I-K-G"} +{"text": "### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-V-G-M-P-K-I-R-R-P-Q-L-V-S-A-T-M-T-V-I-D-R-V-G-L-H-G-A-S-V-S-L-I-S-Q-E-A-G-V-S-S-G-I-I-N-H-Y-F-G-G-K-H-G-L-L-E-E-T-M-R-D-I-L-R-Q-L-S-C-D-A-T-K-R-L-N-L-L-P-K-Q-A-H-M-Q-R-I-N-A-I-L-D-A-N-F-V-G-F-Q-S-E-S-K-V-I-K-T-W-L-A-F-W-S-Y-S-M-H-D-E-A-L-K-R-L-Q-R-V-N-E-K-R-L-L-S-H-L-K-R-E-L-K-A-L-M-S-K-E-Q-A-D-I-V-A-Q-G-I-A-A-L-I-D-G-I-W-L-R-G-A-L-N-P-E-G-I-N-A-N-K-A-R-I-I-I-N-D-Y-L-E-K-Q-L-T-F-Y-S-Q-Q"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-V-L-E-I-L-T-A-P-D-P-R-L-R-V-Q-S-K-E-V-T-D-V-A-A-V-Q-T-L-I-D-D-L-L-E-T-L-Y-E-T-D-N-G-V-G-L-A-A-P-Q-V-G-R-E-E-A-I-V-V-I-D-L-S-E-N-R-D-E-P-L-V-L-V-N-P-K-V-V-S-G-S-N-K-E-M-G-Q-E-G-C-L-S-V-P-D-Y-Y-A-D-V-E-R-Y-T-S-V-V-V-E-A-L-D-R-D-G-K-P-L-R-I-E-T-S-E-F-L-A-I-V-M-Q-H-E-I-D-H-L-S-G-N-L-F-I-D-Y-L-S-P-L-K-Q-Q-M-A-M-K-K-V-K-K-H-N-K-L-R-A-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-D-K-T-L-K-F-T-E-S-H-E-W-V-R-D-N-G-D-G-T-V-T-I-G-I-S-E-H-A-Q-E-M-L-G-D-V-V-F-V-E-L-P-E-L-E-A-E-I-E-A-G-E-S-F-S-L-V-E-S-V-K-A-A-S-D-I-Y-A-P-V-T-G-E-V-V-E-V-N-E-E-L-S-D-S-P-E-L-I-N-E-E-P-Y-E-G-G-W-I-V-K-V-K-L-S-D-P-S-E-L-D-N-L-K-D-A-E-E-Y-L-N-S-I-E-E-D"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-Q-K-T-T-R-T-M-P-A-H-K-H-I-A-L-V-A-H-D-N-Y-K-P-E-L-L-R-W-V-K-E-N-K-E-K-L-Q-S-H-F-L-Y-A-T-G-T-T-G-H-M-L-S-R-E-T-G-L-A-I-K-S-M-I-S-G-P-M-G-G-D-Q-Q-L-G-A-L-I-S-E-G-K-I-D-M-L-I-F-F-W-D-P-L-N-A-V-P-H-D-P-D-V-K-A-L-L-R-I-A-S-V-W-N-I-P-V-A-T-N-R-A-T-A-K-F-L-F-E-S-P-L-L-N-E-E-V-D-V-E-I-P-D-Y-Q-A-Y-L-A-G-R-T"} +{"text": "### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-T-A-P-T-K-M-T-F-F-S-R-F-E-A-D-I-L-A-G-K-K-T-I-T-I-R-D-E-S-E-K-D-Y-Q-P-G-T-T-V-E-V-S-T-L-E-E-G-R-V-F-C-Q-L-K-I-L-S-V-E-P-I-A-F-S-A-L-N-E-F-H-A-E-Q-E-N-M-T-L-E-T-L-K-E-V-I-Q-E-I-Y-P-G-I-E-Q-L-Y-V-I-Q-Y-Q-R-V"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-T-E-Y-I-L-L-L-I-G-T-V-L-V-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-L-E-T-A-I-G-M-G-L-A-T-T-F-V-L-T-M-A-S-V-C-A-Y-L-V-E-S-Y-I-L-E-P-L-H-I-E-Y-L-R-T-M-S-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-V-V-H-K-T-S-P-T-L-Y-R-L-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-I-N-E-N-H-S-F-V-E-S-I-I-Y-G-F-G-A-A-V-G-F-S-L-V-L-I-L-F-A-S-M-R-E-R-I-S-A-A-D-V-P-A-P-F-K-G-A-S-I-A-M-I-T-A-G-L-M-S-L-A-F-M-G-F-T-G-L-V-K"} +{"text": "### FUNCTION Phosphorelay protein which receives a sensory signal from a sensor kinase and transmit it to LuxO At low cell density, a phosphoryl group is transferred from the sensor kinase, probably on His-56 and this phosphoryl group is further transferred to LuxO ### SEQUENCE -M-E-L-L-N-Q-K-K-I-A-S-L-T-E-E-I-G-A-D-N-V-P-V-L-L-E-I-F-L-S-E-L-E-S-Y-L-K-V-L-C-D-A-T-Y-S-D-K-L-V-Y-L-K-D-I-S-H-A-L-K-S-S-A-A-S-F-G-A-D-A-L-C-H-F-A-V-E-I-D-T-R-A-K-E-G-D-A-L-D-E-T-Q-D-V-V-A-M-I-D-R-L-H-Q-T-Q-Q-A-Y-L-S-W-Q-A-N-G-F"} +{"text": "### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-S-Q-F-T-H-I-N-A-S-G-E-A-N-M-V-D-V-S-A-K-A-E-T-V-R-E-A-R-A-E-A-F-V-H-M-A-P-E-T-L-Q-L-I-V-S-G-Q-H-H-K-G-D-V-F-A-T-A-R-I-A-G-I-Q-A-A-K-K-T-W-D-L-I-P-L-C-H-P-L-L-L-S-K-V-E-V-Q-L-Q-A-I-E-A-E-N-K-V-R-I-E-S-V-C-K-L-A-G-K-T-G-V-E-M-E-A-L-T-A-A-S-V-A-A-L-T-I-Y-D-M-C-K-A-V-Q-K-D-M-V-I-G-P-V-R-L-L-E-K-T-G-G-K-S-G-H-F-K-V-E-A"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-E-N-Y-Q-L-V-L-A-S-T-S-P-F-R-Q-Q-L-L-E-K-L-A-I-P-F-S-T-L-S-P-N-C-D-E-T-P-L-E-G-E-S-P-Q-Q-L-V-L-R-L-A-E-S-K-A-Q-S-C-Q-I-N-Q-P-S-L-V-I-G-S-D-Q-V-C-V-I-N-G-N-I-V-G-K-P-H-N-R-Q-N-A-I-A-Q-L-T-A-Q-S-G-Q-S-I-V-F-Y-T-G-L-A-V-Y-N-S-E-T-G-E-T-R-S-C-I-D-E-F-K-V-H-F-R-P-L-T-Q-A-Q-I-V-R-Y-V-D-K-E-Q-P-F-Y-C-A-G-S-F-K-S-E-G-L-G-I-A-L-F-E-K-L-E-G-K-D-P-N-T-L-V-G-L-P-L-I-D-L-I-D-L-L-A-Q-Q-G-M-Q-V-L-G"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-N-L-E-E-R-V-K-K-I-I-V-E-Q-L-G-V-D-E-S-E-V-K-N-E-A-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-A-A-I-D-Y-V-T-A-N-A-Q"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-R-L-C-A-E-Q-T-H-L-S-A-K-E-I-E-D-A-V-K-D-I-L-E-H-M-A-S-T-L-E-S-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-E-P-R-V-G-R-N-P-K-T-G-D-K-V-E-L-E-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-E-R-V-N-I-G"} +{"text": "### FUNCTION Participates in the translocation of lipoproteins from the inner membrane to the outer membrane Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate ### SEQUENCE -M-K-K-W-L-V-V-F-F-L-S-A-S-A-L-A-N-P-Q-Q-E-L-N-Q-R-L-G-M-N-D-G-F-S-A-N-F-N-Q-T-V-T-S-P-E-G-E-V-V-M-E-G-E-G-S-V-D-I-A-R-P-S-L-F-R-W-S-T-S-L-P-D-E-N-L-L-V-S-D-G-K-T-L-W-Y-Y-S-P-F-I-E-Q-V-S-I-Y-W-Q-E-Q-A-V-Q-Q-T-P-F-V-L-L-T-R-N-Q-S-S-D-W-E-N-Y-Q-I-T-Q-D-G-N-V-F-T-L-V-P-K-A-A-D-S-T-Q-G-Q-F-Q-I-D-I-D-A-K-G-I-V-H-G-F-N-V-I-E-Q-D-G-Q-K-G-I-F-K-F-T-D-M-K-L-G-K-P-A-A-A-R-F-T-F-N-I-P-E-G-V-E-V-D-D-Q-R-N"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-K-F-E-A-V-V-R-T-E-L-G-K-G-A-S-R-R-L-R-L-A-G-Q-F-P-A-V-V-Y-G-G-E-A-A-P-V-A-V-A-L-N-H-D-D-I-V-N-Q-M-D-K-P-E-F-Y-E-A-I-T-L-V-I-G-G-E-E-V-K-V-K-P-Q-D-V-Q-R-H-A-F-K-P-K-V-E-H-M-D-F-I-R-I"} +{"text": "### FUNCTION Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ ### SEQUENCE -M-L-K-P-S-D-K-W-S-W-Y-F-D-K-P-S-G-R-L-M-L-D-L-G-D-R-Y-L-F-Q-T-N-L-S-D-K-L-L-V-D-C-A-F-S-Y-N-D-F-T-V-D-D-A-S-A-F-Q-T-F-K-E-C-L-S-S-L-D-L-S-E-Y-R-R-D-E-L-T-L-Y-C-V-A-A-K-R-F-H-K-P-V-Q-P-K-S-W-F-F-H-S-T-G-S-D-Y-Q-P-S-E-G-E-L-V-Q-L-Q-N-G-L-N-Q-G-L-F-I-V-L-E-A-G-D-N-A-S-L-V-S-C-V-E-L-E-G-F-M-L-S-G-S-K-S-L-S-Y-G-E-A-I-K-V-M-H-D-R-M-S-T-A-A-R-M-N-T-L-M-P-M-A-L-V-G"} +{"text": "### FUNCTION Required for spatial organization of the terminus region of the chromosome during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-Q-L-E-N-L-E-C-G-W-K-W-Q-Y-L-I-N-K-W-K-D-G-E-T-I-T-K-Y-I-D-S-S-E-A-D-H-A-V-S-E-L-R-K-L-E-H-E-P-T-K-V-L-E-W-I-D-L-H-M-A-E-E-L-D-K-K-L-K-Q-A-I-R-G-K-R-K-R-H-F-N-A-E-Q-I-H-T-K-K-K-S-I-D-L-D-Y-R-V-W-E-K-L-S-T-R-A-N-E-L-G-C-T-L-S-D-A-I-E-Y-L-L-S-E-A-S-R-S-E-K-A-S-A-A-V-S-T-L-K-E-D-L-S-K-L-L-S-D"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-D-L-A-E-N-L-F-E-K-L-G-F-S-K-R-D-A-K-D-T-V-E-V-F-F-E-E-I-R-K-A-L-E-N-G-E-Q-V-K-L-S-G-F-G-N-F-D-L-R-D-K-N-E-R-P-G-R-N-P-K-T-G-E-D-I-P-I-T-A-R-R-V-V-T-F-R-P-G-Q-K-L-K-A-R-V-E-N-L-K"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-K-N-F-E-W-I-T-P-D-S-D-L-L-E-K-E-I-T-Q-I-Q-P-P-K-K-Y-N-V-V-L-N-N-D-D-Y-T-P-M-D-F-V-I-D-V-L-E-R-F-F-S-H-D-L-D-K-A-T-Q-I-M-L-K-V-H-Y-E-G-K-A-I-C-G-T-Y-S-A-E-I-A-E-T-K-V-A-Q-V-T-M-Y-S-R-E-N-E-H-P-L-L-C-T-M-E-Q-A"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-R-T-S-H-M-L-E-Q-L-M-E-A-L-R-C-L-P-G-V-G-P-K-S-A-Q-R-M-A-F-H-L-L-Q-R-D-R-K-G-G-L-Q-L-A-D-A-L-S-H-A-M-T-E-I-G-H-C-N-E-C-R-T-F-T-E-E-D-V-C-H-I-C-N-N-P-K-R-Q-E-N-G-L-L-C-V-V-E-S-P-A-D-I-A-A-V-E-A-T-G-Q-F-S-G-R-Y-F-V-L-M-G-H-L-S-P-L-D-G-I-G-P-S-D-I-G-L-D-V-L-D-Y-R-L-R-R-G-D-I-K-E-V-I-L-A-T-N-P-T-V-E-G-E-A-T-A-H-Y-I-A-E-L-C-R-E-H-K-V-D-A-S-R-I-A-H-G-V-P-V-G-G-E-L-E-L-V-D-G-T-T-L-S-H-S-L-L-G-R-H-K-L-N"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-G-G-M-G-N-L-M-K-Q-A-Q-Q-M-Q-E-R-M-Q-K-L-Q-E-E-I-A-X-M-E-V-V-G-E-S-G-A-G-L-V-K-V-T-I-T-G-S-H-S-V-R-R-V-N-I-D-E-S-L-M-E-D-D-K-E-M-L-E-D-L-I-A-A-A-F-N-D-A-A-R-R-V-E-E-T-Q-K-E-K-M-A-A-I-T-G-G-M-Q-L-P-P-G-M-K-M-P-F"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-T-N-T-I-A-Q-I-Q-A-S-I-K-S-I-P-D-Y-P-K-P-G-I-L-F-R-D-V-T-S-L-L-E-D-A-Q-A-Y-Q-A-T-I-Q-L-L-V-D-K-Y-K-D-M-G-F-T-K-V-V-G-T-E-A-R-G-F-L-F-G-A-P-L-A-L-Q-L-G-V-G-F-V-P-V-R-K-P-G-K-L-P-R-N-T-I-A-Q-S-Y-E-L-E-Y-G-V-D-T-L-E-I-H-T-D-A-I-V-E-G-D-K-V-L-V-V-D-D-L-L-A-T-G-G-T-I-E-A-T-T-K-L-I-R-Q-L-G-G-V-V-E-H-A-A-F-V-I-N-L-P-E-I-G-G-D-K-R-L-E-G-L-G-L-N-V-Y-S-I-C-E-F-E-G-H"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-T-T-E-K-K-T-M-N-I-S-E-I-Q-E-L-L-P-H-R-Y-P-F-L-L-I-D-R-V-V-D-F-Q-E-E-K-Y-L-H-A-I-K-N-V-S-V-N-E-P-Q-F-T-G-H-F-P-Q-L-P-V-F-P-G-V-L-I-L-E-A-M-A-Q-A-T-G-L-L-A-F-K-S-F-G-A-P-S-E-N-E-L-Y-Y-F-A-S-V-D-G-A-K-F-R-K-P-V-V-P-G-D-Q-L-I-I-E-V-E-F-I-K-E-R-R-G-I-A-A-F-T-G-V-A-K-V-D-G-D-V-V-C-S-A-E-L-K-C-A-R-R-E-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-N-A-E-T-K-A-A-I-V-A-D-Y-A-R-G-E-G-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-S-I-N-H-L-Q-G-H-F-Q-A-H-K-G-D-H-H-S-R-R-G-L-L-R-M-V-S-R-R-R-K-L-L-D-Y-L-K-G-K-D-L-A-R-Y-Q-D-L-I-K-R-L-G-L-R-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-K-D-F-S-R-T-Q-R-V-S-Q-Q-L-Q-K-E-L-A-M-I-L-Q-R-E-V-R-D-S-R-L-G-M-V-T-I-S-D-V-E-V-S-R-D-L-A-Y-A-K-V-F-V-T-F-L-C-V-G-E-Q-T-P-E-S-C-L-A-A-L-R-E-H-E-V-H-I-R-M-M-L-G-K-R-I-R-L-R-L-T-P-E-V-R-F-Y-Y-D-N-T-L-V-E-G-M-R-M-S-N-L-V-T-E-V-V-N-K-D-K-I-K-Q-K-D-A-G-R-E-D-E-E"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-G-L-E-R-Q-L-T-E-M-L-E-S-A-V-V-A-S-G-Y-E-L-V-G-L-E-F-I-R-A-G-E-H-S-T-L-R-I-Y-I-D-H-E-N-G-I-T-V-E-D-C-A-E-V-S-H-Q-V-S-A-V-L-D-V-E-D-P-I-S-V-A-Y-S-L-E-V-S-S-P-G-L-D-R-P-L-F-K-P-A-H-Y-E-Q-F-I-G-Q-E-V-N-V-V-L-K-M-A-V-A-N-R-R-K-W-K-G-E-I-H-S-V-D-G-E-A-I-T-L-T-V-D-G-Q-Q-E-E-F-A-L-S-N-I-S-K-A-N-L-I-P-K-F"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-E-K-V-P-M-T-A-R-G-E-Q-L-L-R-K-E-L-E-R-L-L-K-R-R-P-L-I-T-E-A-I-A-E-A-R-E-L-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-E-Q-G-I-C-E-A-Q-I-R-D-I-E-Y-K-L-S-V-A-Q-V-I-D-V-S-K-M-E-N-N-G-K-V-I-F-G-A-T-V-T-L-I-D-C-D-T-E-E-E-K-T-Y-Q-I-V-G-D-D-E-A-D-I-K-S-G-R-I-S-V-N-S-P-I-A-R-G-L-I-G-K-M-E-G-D-E-V-A-I-S-T-P-G-G-M-K-D-F-E-I-D-S-V-E-Y-R"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-D-I-N-L-P-L-S-F-S-D-A-A-A-A-R-V-K-M-L-I-A-E-E-E-N-P-A-L-K-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-S-V-N-E-G-D-T-T-I-E-N-S-G-V-T-L-V-V-D-P-M-S-L-Q-Y-L-I-G-G-V-V-D-Y-T-E-G-L-E-G-S-R-F-F-V-N-N-P-N-A-T-T-T-C-G-C-G-A-S-F-S-V"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-T-K-I-T-I-V-K-C-P-Q-C-G-T-N-V-E-W-G-E-Q-S-P-H-R-P-F-C-S-K-K-C-Q-M-I-D-F-G-E-W-A-D-E-E-N-A-I-P-G-A-P-D-M-S-D-S-D-G-W-S-E-E-Q-Y"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-N-I-I-K-A-L-E-Q-E-Q-M-K-Q-D-L-P-K-F-A-P-G-D-T-V-V-V-Q-V-K-V-K-E-G-N-R-E-R-L-Q-A-Y-E-G-V-V-I-A-I-R-N-R-G-L-H-S-A-F-T-V-R-K-I-S-N-G-E-G-V-E-R-T-F-Q-T-H-S-P-V-V-D-S-I-E-V-K-R-R-G-A-V-R-R-A-K-L-Y-Y-L-R-E-R-S-G-K-S-A-R-I-K-E-K-L-A-K-K"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-M-K-G-K-E-T-M-S-D-E-R-I-V-V-G-K-F-G-S-T-Y-G-I-R-G-W-L-K-V-F-S-Y-T-D-N-A-E-S-L-F-D-Y-S-P-W-Y-V-N-Q-K-G-E-W-V-E-F-K-V-E-S-W-K-R-H-N-K-G-M-V-A-K-L-E-G-L-D-V-R-E-D-A-H-L-L-T-N-L-E-I-A-I-D-P-A-V-L-P-E-L-S-E-D-E-F-Y-W-R-E-L-F-G-M-Q-V-V-T-T-N-G-Y-D-L-G-V-V-T-D-M-L-E-T-G-S-N-D-V-L-V-V-K-A-N-L-K-D-A-F-G-Q-K-E-R-L-I-P-F-L-E-E-Q-V-I-I-K-V-D-R-E-A-Q-R-I-E-V-D-W-D-P-G-F"} +{"text": "### FUNCTION Catalyzes the decarboxylation of oxaloacetate coupled to Na translocation ### SEQUENCE -M-T-N-I-G-S-L-L-V-D-A-A-A-L-M-V-T-G-M-G-V-V-F-I-F-L-T-I-L-I-F-L-V-R-L-M-S-K-L-V-P-Q-E-V-P-P-P-I-T-A-P-K-A-V-K-N-Q-A-N-H-T-S-T-V-S-P-Q-V-V-A-A-I-S-A-A-I-H-Q-H-R-A-S-V-A-K"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-M-I-G-D-E-V-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-V-N-A-P-K-D-V-S-V-H-R-E-E-I-Y-M-R-I-Q-A-E-K-G-N-V-T-P-G-N-Y"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-H-H-R-F-T-P-P-M-M-S-C-K-D-T-A-I-Q-L-L-S-R-R-D-H-G-Q-Y-E-L-R-Q-K-L-T-V-K-G-Y-A-S-Q-D-I-E-S-A-M-H-F-C-L-E-H-G-Y-L-D-D-L-R-Y-A-K-S-Q-I-R-Q-H-V-G-K-G-H-G-E-R-R-I-R-Q-E-L-S-L-K-Q-V-S-D-S-V-V-E-N-A-F-A-E-E-P-Q-D-W-F-E-L-A-K-S-V-A-M-K-K-F-N-G-V-K-A-K-E-Q-K-E-Y-A-K-Q-V-R-F-L-Q-Y-R-G-F-S-F-E-Q-I-R-Y-A-L-S-D-E-A"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-L-F-I-L-V-L-T-L-L-F-G-W-L-Q-Y-T-L-W-F-G-K-N-G-V-S-D-Y-Y-T-I-E-S-D-I-E-A-Q-Q-L-V-N-T-K-L-Q-A-R-N-S-E-M-Y-A-E-I-D-D-L-K-Q-G-L-D-A-I-E-E-R-A-R-H-E-L-G-M-L-K-E-G-E-T-F-Y-R-I-V-G-E-E-N-Q"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-V-G-L-G-T-D-I-A-E-I-E-R-V-E-K-A-L-A-R-S-G-V-A-F-A-E-R-I-L-S-A-Q-E-M-E-T-F-V-S-L-K-Q-Q-G-R-F-L-A-K-R-F-A-A-K-E-A-A-S-K-A-L-G-T-G-I-A-H-G-V-S-F-Q-D-F-T-I-K-N-D-D-N-G-K-P-Y-L-Q-L-A-G-R-A-A-E-L-A-H-Q-M-G-V-C-H-T-H-L-S-L-S-D-E-R-H-Y-A-V-A-T-V-I-F-E-S"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-R-T-I-M-A-F-D-F-G-T-K-S-I-G-S-A-I-G-Q-E-I-T-G-T-A-S-P-L-K-A-F-K-A-N-D-G-I-P-N-W-D-E-I-E-K-Q-I-K-E-W-Q-P-N-L-L-V-V-G-L-P-T-D-L-H-G-K-A-L-E-T-I-T-P-R-A-K-K-F-A-Q-R-L-Q-G-R-F-G-L-P-V-E-L-H-D-E-R-L-S-T-T-E-A-R-S-E-L-F-S-M-G-G-Y-K-A-L-S-K-G-N-V-D-C-Q-S-A-V-I-I-L-E-S-W-F-E-A-Q-W-G"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-N-K-E-T-K-L-Q-V-E-A-I-K-N-G-T-V-I-D-H-I-P-A-Q-V-G-I-K-V-L-K-L-F-D-M-H-N-S-S-Q-R-V-T-I-G-L-N-L-P-S-S-A-L-G-N-K-D-L-L-K-I-E-N-V-F-I-N-E-E-Q-A-S-K-L-A-L-Y-A-P-H-A-T-V-N-Q-I-E-D-Y-Q-V-V-K-K-L-A-L-E-L-P-E-F-V-S-D-V-F-E-C-P-N-T-N-C-I-T-H-N-E-P-V-A-S-N-F-R-V-F-E-K-K-G-D-V-R-L-K-C-K-Y-C-E-K-V-F-S-R-E-I-V-T-E-R"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-S-R-G-I-N-K-V-I-L-V-G-N-L-G-N-D-P-E-I-R-Y-M-P-S-G-G-A-V-A-N-I-T-V-A-T-S-E-T-W-R-D-K-A-T-G-E-P-R-E-K-T-E-W-H-R-V-T-L-Y-G-K-L-A-E-V-A-G-E-Y-L-R-K-G-S-Q-V-Y-I-E-G-Q-L-Q-T-R-K-W-Q-D-Q-N-G-Q-D-R-Y-S-T-E-V-V-V-Q-G-Y-N-G-I-M-Q-M-L-G-G-R-Q-Q-Q-G-G-A-P-A-M-G-G-A-P-Q-Q-Q-Q-G-G-W-G-Q-P-Q-Q-P-A-A-Q-P-S-Y-Q-K-Q-A-P-A-Q-Q-Q-P-M-Q-S-Q-P-Q-Y-N-E-P-P-M-D-F-D-D-D-I-P-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-D-K-I-G-N-L-G-S-L-G-D-T-V-N-V-K-S-G-Y-A-R-N-F-L-I-P-Q-G-K-A-V-M-A-T-K-G-N-V-E-M-F-E-A-R-R-A-E-L-E-A-K-V-A-E-Q-L-A-S-A-E-A-R-A-E-K-V-N-A-L-E-A-V-V-I-A-S-K-A-G-D-E-G-K-L-F-G-S-I-G-T-R-D-I-A-D-A-I-T-A-A-G-V-E-V-V-K-S-E-V-R-L-P-E-G-A-L-R-T-T-G-E-F-E-I-S-V-Q-L-H-S-E-V-F-A-T-V-K-L-Q-V-V-A-E"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-T-N-R-M-E-L-S-G-T-V-V-K-D-P-I-R-S-Q-S-P-A-G-I-S-H-C-R-F-W-L-E-H-R-S-V-V-V-E-A-D-L-P-R-Q-V-F-C-R-M-P-V-V-V-S-G-K-G-S-Q-D-I-T-Q-Q-I-V-L-G-S-N-I-K-V-S-G-F-V-A-Y-Q-T-G-R-N-G-V-G-K-L-V-L-H-A-D-D-I-I-H-I"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-A-G-M-I-E-R-Y-T-G-S-I-T-E-A-G-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-V-L-M-N-V-E-A-D-Q-A-V-I-D-E-L-E-T-A-F-R-Y-N-D-A-V-L-R-N-M-I-M-R-T-K-A-A-I-T-E-P-S-I-M-L-K-Q-K-E-E-R-A-P-R-R-E-A-E-A-K-E-F-A-A-E"} +{"text": "### FUNCTION This regulatory protein, when combined with SAM represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-A-D-W-N-G-E-Y-I-S-P-Y-A-E-H-G-K-K-S-E-Q-V-K-K-I-T-V-S-I-P-L-K-V-L-K-V-L-T-D-E-R-T-R-R-Q-I-N-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-Y-T-G-Q-P-L-P-T-D-E-D-L-R-K-D-R-P-D-D-I-P-T-E-A-K-E-L-M-T-A-M-G-I-E-F-E-A-Y-D-D"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-G-I-H-P-E-Y-K-A-V-N-A-T-C-S-C-G-N-S-F-V-F-N-S-T-L-D-K-E-S-I-H-L-D-V-C-D-K-C-H-P-F-Y-T-G-K-Q-R-I-V-D-T-G-G-R-V-D-R-F-N-K-R-F-G-A-L-S-S-G-K-K"} +{"text": "### FUNCTION Globally modulates RNA abundance by binding to RNase E and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome Modulates RNA-binding and helicase activities of the degradosome ### SEQUENCE -M-E-Y-N-T-S-A-L-C-D-I-Y-M-D-Q-V-D-V-V-E-P-M-F-S-N-F-G-G-R-A-S-F-A-G-Q-I-T-T-V-K-C-F-E-D-N-A-L-I-R-E-T-L-E-Q-D-G-V-G-R-V-L-L-V-D-G-G-G-S-L-R-R-A-L-L-D-G-E-L-A-A-I-A-E-E-N-E-W-E-G-I-V-V-Y-G-C-V-R-E-V-D-E-L-E-D-M-N-I-G-I-Q-A-L-A-S-I-P-V-G-A-A-M-Q-G-V-G-E-V-D-V-P-V-N-F-G-G-V-T-F-L-P-E-D-Y-L-Y-A-D-T-T-G-I-I-L-S-Q-E-P-L-S-A-D-L-E-E-D-E-E-E-P-E-L-L-D"} +{"text": "### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-F-E-V-L-E-K-L-E-A-K-I-Q-T-A-V-D-T-I-A-L-L-Q-M-E-V-D-E-L-K-E-D-K-A-K-L-E-T-E-A-N-E-L-R-A-Q-R-E-Q-L-E-Q-K-A-Q-Q-T-Q-Q-E-H-A-Q-W-Q-E-R-I-R-A-L-L-G-K-M-E-D-V-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-I-G-Q-R-K-I-L-P-D-P-K-F-K-S-E-L-L-A-K-F-V-N-I-L-M-V-D-G-K-K-S-V-A-E-K-I-V-Y-T-A-L-D-T-M-A-E-K-S-G-K-D-H-L-A-V-F-E-E-A-L-E-N-V-R-P-A-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-P-V-R-R-N-A-L-A-M-R-W-L-V-E-A-A-R-K-R-G-E-K-S-M-A-A-R-L-A-A-E-M-L-D-A-S-D-N-K-G-T-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-N-Q-L-V-R-K-P-R-A-K-Q-V-V-K-S-N-V-P-A-L-E-A-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-T-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-A-L-D-C-A-G-V-N-N-R-K-Q-G-R-S-K-Y-G-V-K-R-P-K-S"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-S-T-L-R-Y-T-L-V-V-N-G-S-V-Y-G-S-Q-S-A-R-T-A-Y-Q-F-A-S-A-L-I-E-K-G-H-T-L-V-S-V-F-F-Y-Q-D-G-V-T-N-G-T-E-L-T-V-P-A-N-D-E-F-H-L-T-K-A-W-Q-Q-L-A-K-Q-H-N-V-R-L-E-T-C-V-A-A-A-L-R-R-G-V-V-S-Q-S-E-A-S-Q-H-G-L-L-Q-H-N-L-A-D-G-F-E-Q-A-G-L-G-S-L-A-E-A-M-L-T-Q-D-R-V-V-Q-F"} +{"text": "### FUNCTION Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress May require iron for activity ### SEQUENCE -M-Q-L-T-S-F-T-D-Y-A-L-R-T-L-I-Y-L-A-S-L-P-D-N-E-Q-T-N-I-T-D-V-T-E-L-F-G-V-S-R-N-H-M-V-K-V-I-N-R-L-G-Q-L-N-Y-I-Q-T-V-R-G-K-N-G-G-I-R-L-N-R-P-A-K-T-I-L-V-G-E-V-V-R-D-L-E-P-L-D-L-V-N-C-S-V-E-F-C-H-I-T-P-A-C-R-L-K-E-R-L-Y-R-A-K-L-A-F-L-A-E-L-D-D-C-S-I-A-E-L-L-D-D-N-A-E-L-L-I-L-L-Q-K-A"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-I-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-N-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-P-V-S-H-H-S-G-E-R-G-S-D-R-P-S-E-K-S-E-D"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-S-F-S-D-Q-N-L-I-W-I-D-L-E-M-T-G-L-D-P-D-V-H-K-I-I-E-I-A-S-I-V-T-D-S-E-L-N-I-L-A-E-G-P-V-L-A-I-H-Q-S-E-E-E-L-A-K-M-D-E-W-C-T-N-T-H-T-G-S-G-L-V-E-R-V-R-G-S-Q-I-T-E-Q-E-A-V-E-Q-T-I-A-F-L-E-K-W-V-P-K-G-V-S-P-I-C-G-N-S-I-G-Q-D-R-R-F-L-Y-R-H-M-P-E-L-E-G-Y-F-H-Y-R-Y-I-D-V-S-T-L-K-E-L-T-R-R-W-N-P-E-V-L-K-G-F-S-K-Q-G-T-H-L-A-L-D-D-I-R-E-S-I-A-E-L-K-F-Y-R-Q-T-I-F-K-I"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-A-E-A-A-P-Q-D-T-Q-Q-H-F-A-I-Q-R-I-F-L-K-D-V-S-F-E-A-P-N-S-P-V-M-F-Q-K-E-W-N-P-D-V-K-L-D-L-D-T-Q-S-R-E-L-G-E-G-V-Y-E-V-I-L-R-L-T-V-T-V-K-N-A-E-E-T-A-F-L-C-E-V-Q-Q-G-G-I-F-T-A-E-K-M-E-A-G-Q-L-A-H-C-L-G-A-F-C-P-N-I-L-F-P-Y-A-R-E-T-I-S-S-L-V-V-K-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-M-N-Y-L-Q-Q-Q-A-A-Q-Q-G-A-E-Q-A"} +{"text": "### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-S-N-R-K-P-Y-V-R-E-V-K-R-T-W-W-K-D-H-P-F-Y-R-F-Y-M-L-R-E-A-T-V-L-P-L-I-L-F-T-L-F-L-T-V-G-L-G-S-L-V-K-G-P-E-A-W-Q-T-W-L-N-F-M-A-N-P-V-V-I-A-I-N-I-V-A-L-L-G-S-L-L-H-A-H-T-F-F-S-M-M-P-Q-V-M-P-I-R-L-K-G-K-P-V-D-K-K-I-I-V-L-A-Q-W-A-A-V-A-F-I-S-L-I-V-L-I-V-V"} +{"text": "### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-K-P-N-Y-N-V-D-R-A-P-K-R-S-D-E-P-V-W-W-S-L-F-G-A-G-G-T-W-F-A-M-I-T-P-V-T-V-L-V-L-G-I-L-V-P-M-G-V-I-N-A-E-A-L-S-Y-D-R-V-V-S-F-A-T-S-I-I-G-A-L-F-I-I-A-T-L-A-L-P-M-W-H-A-M-H-R-V-H-H-G-M-H-D-L-K-F-H-T-G-V-V-G-K-I-A-C-Y-A-V-A-G-L-I-S-A-L-A-V-V-F-I-F-M-L"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-T-V-S-T-N-E-F-K-G-G-L-K-L-M-I-D-S-E-P-C-V-I-L-E-N-E-Y-V-K-P-G-K-G-Q-A-F-N-R-V-K-I-R-K-L-L-S-G-K-V-L-E-K-T-F-K-S-G-D-T-C-E-V-A-D-V-M-D-I-D-L-D-Y-L-Y-S-D-G-E-F-Y-H-F-M-N-N-E-T-F-E-Q-I-A-A-D-A-K-A-V-G-E-N-V-K-W-L-V-E-N-N-T-C-M-L-T-L-W-N-G-N-P-I-A-V-T-P-P-N-F-V-E-L-E-V-I-E-T-D-P-G-L-K-G-D-T-Q-G-T-G-G-K-P-A-T-L-S-T-G-A-V-V-R-V-P-L-F-I-Q-I-G-E-V-I-K-V-D-T-R-S-S-E-Y-V-G-R-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-I-T-N-E-Q-I-L-D-A-I-A-E-M-S-V-T-Q-V-V-E-L-I-S-A-M-E-E-K-F-G-V-T-A-A-A-A-V-V-A-G-G-A-A-A-G-A-A-V-E-E-Q-T-E-F-N-V-I-L-A-S-A-G-A-N-K-V-A-V-I-K-A-V-R-G-A-T-G-L-G-L-K-E-A-K-A-L-V-D-G-A-P-A-A-L-K-E-G-V-E-K-A-E-A-E-A-L-K-K-E-L-E-E-A-G-A-T-V-E-I-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-Q-D-K-K-A-I-V-A-E-V-N-E-A-A-A-G-A-L-S-A-V-V-A-D-S-R-G-V-S-V-D-A-M-T-T-L-R-K-Q-A-R-E-A-G-V-Y-M-K-V-V-R-N-T-L-A-R-R-A-V-E-G-T-Q-Y-E-C-L-T-D-T-F-T-G-P-S-L-I-A-F-S-N-E-H-P-G-A-A-A-R-L-F-K-D-F-A-K-E-N-K-K-F-E-I-K-A-A-A-F-E-G-A-L-T-D-A-E-V-L-A-T-L-P-T-Y-D-E-A-I-A-R-L-M-M-C-L-K-E-A-S-A-G-K-L-V-R-T-I-A-A-I-R-D-Q-K-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-A-Y-I-K-L-Q-V-A-A-G-M-A-N-P-S-P-P-V-G-P-A-L-G-Q-R-G-V-N-I-M-E-F-C-K-A-F-N-A-K-T-E-S-M-E-K-G-L-P-V-P-V-V-I-T-V-Y-S-D-R-S-F-T-F-V-T-K-T-S-P-A-A-V-L-L-K-K-A-A-G-I-K-S-G-S-G-R-P-N-T-E-K-V-G-T-V-T-D-A-Q-I-Q-E-I-A-E-A-K-A-A-D-M-T-G-A-D-I-E-A-M-K-R-S-I-A-G-T-A-R-S-M-G-L-V-V-E-G"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-S-E-A-P-K-K-R-W-Y-V-V-Q-A-F-S-G-F-E-G-R-V-A-Q-S-L-R-E-H-I-K-M-H-G-M-E-E-Y-F-G-E-V-L-V-P-T-E-E-V-V-E-M-R-A-G-Q-R-R-K-S-E-R-K-F-F-P-G-Y-V-L-V-Q-M-I-M-N-D-E-S-W-H-L-V-R-S-V-P-R-V-M-G-F-I-G-G-T-S-D-R-P-A-P-I-S-D-K-E-A-D-A-I-L-N-R-L-E-K-A-S-E-A-P-R-P-R-T-M-Y-E-V-G-E-V-V-R-V-N-E-G-P-F-A-D-F-N-G-T-V-E-E-V-D-Y-E-K-S-R-L-K-V-S-V-S-I-F-G-R-A-T-P-V-E-L-E-F-G-Q-V-E-K-L-D"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-N-Q-P-N-S-L-Y-L-A-L-L-I-E-A-K-W-Q-N-P-E-D-F-H-F-S-S-D-F-A-K-H-W-L-L-E-Q-G-S-L-S-R-R-L-A-R-H-C-Q-H-L-T-V-E-L-M-R-N-E-K-S-G-M-G-Q-L-T-R-Q-E-T-Q-G-L-S-P-E-I-C-L-I-R-E-V-V-L-S-G-D-Q-T-P-W-V-L-G-R-T-L-I-P-E-T-T-L-A-D-Q-P-Y-D-L-A-T-L-G-D-I-P-L-G-L-T-V-F-S-A-E-Q-V-E-R-D-A-L-Q-V-A-W-I-E-T-P-Q-G-R-L-L-A-R-R-S-R-L-W-M-N-H-K-P-M-L-V-A-E-L-F-L-P-D-A-P-I-Y-S-R-E-S-V"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-E-Q-F-K-H-I-D-V-Q-G-A-H-A-L-I-S-R-G-E-A-R-L-V-D-I-R-D-P-Q-S-F-A-V-A-H-A-Q-S-A-F-H-L-T-N-D-S-I-V-N-F-M-Q-Q-V-E-F-E-Q-P-V-L-V-M-C-Y-H-G-I-S-S-Q-G-A-A-Q-Y-L-V-N-Q-G-F-E-E-V-Y-S-V-D-G-G-F-E-A-W-H-R-A-S-L-P-V-E-A-S"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-N-T-E-F-H-Q-L-V-D-N-E-L-Q-L-I-E-E-A-I-D-E-S-G-A-D-I-D-Y-E-T-T-G-N-V-M-T-L-E-F-D-D-R-S-Q-I-I-I-N-R-Q-E-P-M-Q-E-I-W-L-A-S-K-S-G-G-F-H-F-Q-Y-K-A-G-Q-W-I-C-S-K-T-G-V-E-F-A-H-M-V-K-Q-E-C-E-K-H-A-G-E-S-I-D-W-A"} +{"text": "### FUNCTION Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide ### SEQUENCE -M-K-V-G-I-I-M-G-S-K-S-D-W-P-T-M-K-L-A-A-E-M-L-D-R-F-G-V-E-Y-E-T-K-V-V-S-A-H-R-T-P-H-L-L-A-E-Y-A-S-T-A-K-E-R-G-L-K-V-I-I-A-G-A-G-G-A-A-H-L-P-G-M-A-A-A-F-T-S-L-P-V-L-G-V-P-V-Q-S-R-A-L-S-G-L-D-S-L-Y-S-I-V-Q-M-P-K-G-I-A-V-G-T-L-A-I-G-E-A-G-A-A-N-A-G-L-L-A-A-Q-I-L-G-T-H-D-E-N-I-M-A-K-V-E-A-F-R-S-E-Q-T-E-S-V-L-A-N-P-N-P-A-E-D"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-V-L-Q-V-L-T-F-P-D-D-R-L-R-T-V-A-K-P-V-E-K-V-T-P-E-I-Q-K-I-V-D-D-M-I-E-T-M-Y-D-E-E-G-I-G-L-A-A-T-Q-V-D-I-H-Q-R-I-V-V-I-D-I-S-E-S-R-N-E-P-M-V-L-I-N-P-E-I-L-E-K-R-G-E-D-G-I-E-E-G-C-L-S-V-P-G-A-R-A-L-V-P-R-A-A-E-V-T-V-K-A-L-D-R-D-G-H-E-F-T-L-E-A-D-D-L-L-A-I-C-I-Q-H-E-L-D-H-L-Q-G-K-L-F-V-D-Y-L-S-P-L-K-R-K-R-I-Q-D-K-L-A-K-I-K-R-F-N-E-K-Q-R"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-A-I-T-F-H-L-D-V-V-S-A-E-K-K-I-F-S-G-R-V-E-T-F-Q-V-T-G-S-E-G-E-L-G-I-F-H-G-H-T-P-L-L-T-A-I-K-P-G-M-V-R-I-V-K-L-H-G-E-E-E-F-I-Y-V-S-G-G-I-V-E-V-Q-P-G-T-A-T-V-L-A-D-T-A-I-R-G-E-E-L-D-A-A-K-A-E-E-A-K-R-R-A-K-E-N-I-L-N-Q-H-G-D-M-D-F-A-Q-A-A-S-E-L-A-K-A-I-A-Q-L-R-V-I-E-L-T-K-K-R-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-D-F-T-T-I-A-R-P-Y-A-K-A-A-F-D-F-A-V-E-K-G-Q-L-D-Q-W-G-Q-M-L-S-F-A-A-E-V-A-Q-N-E-Q-I-S-E-L-L-S-G-S-M-S-A-D-K-L-A-E-L-F-I-A-I-C-G-E-Q-V-D-E-F-G-Q-N-L-L-K-V-M-A-E-N-G-R-L-A-A-L-P-D-V-C-T-L-F-F-V-L-K-K-E-H-E-K-E-I-D-V-E-V-I-S-A-T-E-L-S-D-E-Q-C-A-N-I-S-Q-K-L-E-Q-R-L-E-R-K-V-K-L-N-C-S-V-D-E-A-L-L-G-G-V-I-I-R-A-G-D-L-V-I-D-N-S-A-R-G-R-L-N-R-L-S-D-A-L-Q-S"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-M-N-A-T-L-L-G-Q-A-I-S-F-A-M-F-V-W-F-C-M-K-Y-V-W-P-P-I-M-Q-A-I-E-E-R-Q-K-K-I-A-D-G-L-Q-A-A-E-R-A-A-K-D-L-D-L-A-Q-A-N-A-S-S-Q-L-K-E-A-K-R-T-A-T-E-I-I-E-Q-A-N-K-R-K-A-Q-I-L-D-E-A-R-E-D-A-Q-T-E-R-Q-K-I-L-A-Q-A-E-A-Q-L-E-A-E-R-N-R-A-R-D-E-L-R-K-Q-V-A-T-L-A-V-A-G-A-E-K-I-L-E-R-S-I-D-K-D-A-H-K-D-I-L-D-N-I-T-A-K-L"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-T-Y-A-F-N-R-E-L-R-L-L-T-P-E-H-Y-Q-N-V-F-Q-Q-A-H-R-A-G-S-P-H-F-T-I-I-A-R-N-N-N-L-S-H-P-R-L-G-L-A-V-P-K-K-Q-I-K-T-A-V-G-R-N-R-F-K-R-L-A-R-E-S-F-R-N-T-Q-H-Q-L-P-N-K-D-F-V-V-I-A-K-K-S-A-Q-D-L-S-N-E-E-L-F-K-L-F-D-K-L-W-H-R-L-S-R-P-S-R-G"} +{"text": "### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-S-F-N-P-E-L-A-T-K-T-L-E-A-E-G-L-R-C-P-E-P-V-M-M-V-R-K-T-I-R-T-M-Q-D-G-E-V-L-L-V-K-A-D-D-P-S-T-T-R-D-I-P-S-F-C-R-F-M-D-H-Q-L-I-A-A-Q-T-D-E-L-P-Y-Q-Y-L-I-K-K-G-L"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-S-Q-F-A-I-L-G-F-I-A-L-G-G-A-F-G-A-C-S-R-Y-L-V-S-E-L-C-V-V-L-L-G-R-G-F-P-Y-G-T-L-T-V-N-V-V-G-S-F-I-M-G-L-L-I-A-A-F-E-S-E-L-L-A-T-E-P-W-R-Q-I-I-G-L-G-F-L-G-A-L-T-T-F-S-T-F-S-M-D-N-V-L-L-M-Q-Q-G-A-F-F-K-M-G-L-N-V-V-L-N-V-T-L-S-I-T-A-A-W-V-G-F-Q-L-L-K-S"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-I-S-I-W-Q-L-L-I-I-A-V-I-V-V-L-L-F-G-T-K-K-L-R-G-I-G-S-D-L-G-G-A-I-K-G-F-K-K-A-M-N-E-E-E-S-E-K-K-D-A-D-F-E-P-K-S-L-E-Q-Q-S-K-Q-A-A-T-E-S-K-K-D-K-E-Q-A"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-W-E-L-V-L-I-F-V-V-G-L-V-V-L-G-P-E-R-L-P-H-A-I-R-S-V-A-R-F-V-S-A-A-K-S-M-A-N-S-V-K-D-E-L-A-H-E-L-K-V-Q-E-L-Q-E-N-L-R-K-A-E-Q-M-G-M-E-E-L-S-P-D-L-K-A-S-V-E-Q-L-K-Q-A-A-Q-S-V-N-R-P-Y-A-D-V-S-A-K-N-E-A-T-S-S-S-S-S-D-A-T-H-Q-T-E-A-T-K-T-S-A-A-N-T-K-S-E"} +{"text": "### FUNCTION A GTPase-activating protein that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-S-R-K-K-K-S-R-K-P-G-A-A-G-A-P-E-F-M-V-T-R-N-R-S-E-S-D-V-A-G-R-L-R-K-K-D-K-K-R-K-G-L-K-A-G-G-R-N-S-E-E-G-A-Q-Q-K-H-G-S-S-Q-V-R-D-P-R-L-G-S-K-K-K-I-P-L-I-V-E-P-A-K-K-L-T-K-Q-E-R-R-L-S-A-E-Q-E-L-E-M-L-E-N-D-A-K-L-N-V-L-L-D-R-I-E-S-G-E-N-L-G-R-G-L-Q-Q-Y-V-D-E-K-L-D-R-I-E-Q-L-M-S-Q-L-G-L-L-E-P-E-A-E-E-E-F-E-E-E-A-P-V-R-K-S-R-S-D-D-D-L-L-A-D-F-E-D-F-D-M-D-D-Y-K-G"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-S-N-I-T-I-T-E-A-A-Q-T-H-F-A-N-L-L-G-Q-Q-P-D-G-T-N-I-R-V-F-V-V-N-P-G-T-Q-N-A-E-C-G-V-S-Y-C-P-P-E-A-V-E-A-T-D-T-E-I-P-Y-Q-S-F-S-A-Y-V-D-E-L-S-L-P-F-L-E-D-A-E-I-D-Y-V-T-D-K-M-G-S-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-A-D-D-A-P-L-L-E-R-V-E-Y-A-I-Q-T-Q-V-N-P-Q-L-A-G-H-G-G-H-V-K-L-M-E-I-T-D-A-G-V-A-I-V-A-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-E-G-I-E-K-E-L-L-Q-Q-F-S-G-E-L-T-A-V-R-D-A-T-E-H-D-R-G-D-H-S-Y-Y"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-K-T-K-M-I-T-R-E-G-Y-N-K-L-K-Q-E-L-D-Y-L-W-K-E-H-R-P-E-I-T-Q-K-V-S-W-A-A-S-L-G-D-R-S-E-N-A-D-Y-T-Y-N-K-R-L-L-R-Q-I-D-R-R-V-R-F-L-S-K-F-L-P-E-V-K-I-V-D-Y-A-P-Q-Q-E-G-K-V-F-F-G-A-W-V-E-I-E-N-E-A-G-E-V-M-K-F-R-I-V-G-P-E-E-I-Y-G-D-A-K-G-Y-I-S-I-D-S-P-M-A-R-A-L-L-K-K-E-V-D-D-E-V-Q-V-P-T-P-S-G-I-K-E-W-F-I-N-S-I-E-Y-D-K-G-E"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-D-A-V-E-K-V-G-N-R-F-D-L-V-L-I-A-A-R-R-A-R-Q-M-Q-T-G-G-K-D-S-L-V-P-E-E-N-D-K-P-T-V-I-A-L-R-E-I-E-E-G-L-I-T-K-E-V-L-D-A-R-E-R-Q-E-Q-Q-E-Q-E-A-A-E-L-A-A-V-S-S-I-A-R-N-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA It is important during the early stages of 50S assembly It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-E-L-M-V-K-G-A-A-A-L-T-V-S-E-A-T-F-G-R-E-F-N-E-A-L-V-H-Q-V-V-V-A-Y-A-A-G-A-R-Q-G-T-R-A-Q-K-T-R-S-E-V-S-G-G-G-A-K-P-W-R-Q-K-G-T-G-R-A-R-A-G-T-I-R-S-P-L-W-R-T-G-G-V-T-F-A-A-K-P-Q-D-H-S-Q-K-V-N-K-K-M-Y-R-G-A-M-K-S-I-L-S-E-L-V-R-Q-E-R-L-I-V-V-D-N-F-S-V-E-A-P-K-T-K-E-L-V-A-K-L-K-E-L-E-L-N-D-V-L-I-V-T-G-E-V-D-E-N-L-F-L-A-A-R-N-L-Y-K-V-D-A-R-D-V-A-G-I-D-P-V-S-L-I-A-F-N-K-V-L-M-T-A-D-A-V-K-Q-V-E-E-M-L-A"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-T-Q-E-R-L-L-K-V-L-R-A-P-H-I-S-E-K-A-T-M-A-A-E-K-A-N-T-I-V-F-K-V-A-K-D-A-T-K-K-E-I-K-A-A-V-E-Q-L-F-E-V-E-V-K-S-V-N-T-L-I-T-K-G-K-T-K-R-Q-G-L-R-Q-G-R-R-S-D-V-K-K-A-Y-V-T-L-K-E-G-Q-D-L-D-F-V-G-G-A-E"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-V-E-K-A-V-E-S-G-D-K-K-P-L-K-T-W-S-R-R-S-M-I-I-P-T-M-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-F-V-T-E-E-M-I-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-A-A-D-K-K-A-K-K-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-I-A-K-H-N-F-A-R-I-S-P-Q-K-A-R-L-V-A-D-L-I-R-G-K-S-V-D-Q-A-L-E-I-L-T-F-S-N-K-K-A-A-V-L-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-E-G-A-D-I-D-D-L-N-V-A-K-I-F-V-D-E-G-P-T-M-K-R-I-M-P-R-A-K-G-R-A-D-R-I-L-K-R-S-S-H-I-T-V-V-V-A-D-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-V-H-T-G-R-N-R-G-L-A-K-G-T-E-V-S-F-G-S-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-H-I-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-E-V-R-Q-G-K-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-K-V-M-Y-E-V-D-G-V-P-E-E-L-A-R-E-A-F-R-L-A-A-R-K-L-P-F-K-T-T-F-V-T-K-Q-V-M"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-D-K-I-R-T-Q-L-G-R-V-V-S-D-K-M-D-K-S-I-V-V-A-I-E-R-M-V-K-H-P-I-Y-G-K-F-V-K-R-T-T-K-V-H-A-H-D-E-N-N-E-C-G-I-G-D-T-V-E-I-R-E-C-R-P-L-S-K-T-K-S-W-T-L-V-K-V-V-E-K-A-K-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-M-L-D-A-A-D-N-S-G-A-R-S-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-H-I-G-D-V-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-D-V-L-K-A-V-V-V-R-T-R-K-G-V-R-R-P-D-G-S-V-I-R-F-D-R-N-A-C-V-L-L-N-N-N-T-E-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-G-D-K-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-N-D-E-V-I-V-L-A-G-K-D-K-G-K-K-G-K-V-T-K-V-L-A-T-G-K-V-I-V-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-L-G-I-Q-G-G-I-V-E-Q-E-A-A-I-D-V-S-N-V-A-I-F-N-A-A-T-G-K-A-D-R-I-G-F-R-F-E-D-G-Q-K-V-R-F-F-K-S-N-G-E-T-V-S-N"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-K-S-S-V-V-A-E-L-T-K-Q-F-G-Y-T-S-V-M-Q-V-P-R-I-E-K-I-T-L-N-M-G-V-G-D-A-I-N-D-K-K-L-L-E-N-A-A-A-D-M-A-T-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-V-A-G-F-K-I-R-E-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-D-F-M-E-R-L-I-S-I-A-L-P-R-V-R-D-F-R-G-V-N-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-F-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-S-A-G-T-D-E-E-G-R-A-L-L-A-A-F-N-F-P-F-R-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-E-A-K-R-A-K-L-V-A-K-F-A-E-K-R-A-S-L-K-A-I-I-S-D-V-N-V-S-E-E-D-R-W-N-A-V-L-K-L-Q-T-L-P-R-D-S-S-A-S-R-Q-R-N-R-C-N-Q-T-G-R-P-H-G-Y-L-R-K-F-G-L-S-R-I-K-V-R-E-A-C-M-K-G-E-I-P-G-L-R-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-S-D-M-L-T-R-I-R-N-G-Q-A-A-N-K-V-A-V-K-M-P-S-S-K-L-K-V-A-I-A-A-L-L-K-A-E-G-Y-I-V-D-F-A-V-E-G-E-A-K-P-E-L-E-V-T-L-K-Y-F-Q-A-K-P-V-I-E-Q-L-K-R-V-S-R-P-G-L-R-V-Y-K-K-K-D-D-L-P-S-V-M-G-G-L-G-V-A-V-V-S-T-S-K-G-L-M-S-D-R-A-A-R-K-A-G-L-G-G-E-I-I-C-Y-V-A"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-A-I-P-A-G-V-E-V-K-L-N-G-Q-E-I-T-V-K-G-A-K-G-E-L-S-R-V-I-N-N-A-V-V-I-A-Q-E-E-N-K-L-T-F-G-P-R-E-G-V-A-N-A-W-A-Q-A-G-T-A-R-A-L-V-N-N-M-V-V-G-V-T-E-G-F-T-R-K-L-I-L-K-G-V-G-Y-R-A-A-I-K-G-N-A-V-G-L-T-L-G-F-S-H-P-V-E-H-E-L-P-A-G-I-K-A-E-C-P-S-Q-T-E-I-V-L-T-G-C-D-K-Q-L-I-G-Q-V-A-A-D-I-R-A-Y-R-A-P-E-P-Y-K-G-K-G-I-R-Y-A-D-E-N-V-R-S-K-E-A-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-A-S-R-I-R-R-A-T-R-A-R-R-K-I-A-E-L-G-A-T-R-L-V-V-H-R-T-P-R-H-V-Y-A-Q-V-I-A-A-N-G-S-E-V-I-A-A-A-S-T-V-E-K-A-I-R-E-Q-V-K-Y-T-G-N-I-E-A-A-K-A-V-G-K-A-V-A-E-R-A-L-E-K-G-V-S-T-V-A-F-D-R-S-G-F-Q-Y-H-G-R-V-A-A-L-A-D-S-A-R-E-A-G-L-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-K-E-Q-Q-V-Q-A-N-D-L-Q-E-K-L-I-A-V-N-R-V-S-K-T-V-K-G-G-R-I-M-S-F-T-A-L-T-V-V-G-D-G-N-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-N-M-V-T-I-A-L-N-E-G-T-L-H-H-P-V-K-G-R-H-S-G-S-K-V-Y-M-Q-P-A-A-E-G-T-G-V-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-H-N-V-L-S-K-A-Y-G-S-T-N-P-I-N-I-V-R-A-T-I-D-A-L-V-D-V-K-S-P-E-M-V-A-A-K-R-G-L-T-V-E-A-I-S-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-S-P-A-A-G-S-K-H-A-P-K-R-V-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-K-S-R-S-G-G-K-V-R-P-G-F-E-G-G-Q-M-P-L-K-Q-R-L-P-K-F-G-F-T-S-R-K-S-L-V-S-A-E-V-R-V-A-E-L-A-K-V-T-G-D-V-V-D-L-N-S-L-K-A-A-N-V-I-T-K-N-I-E-N-V-K-I-V-L-S-G-E-I-N-K-A-V-T-V-K-G-L-R-V-T-K-G-A-K-A-A-I-E-A-A-G-G-K-I-E-E"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-A-V-I-A-L-T-A-I-Y-G-I-G-K-T-R-S-K-A-I-L-A-D-V-G-I-A-E-D-V-K-I-S-E-L-T-E-E-Q-I-D-Q-L-R-D-G-V-A-K-Y-T-V-E-G-D-L-R-R-E-V-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-S-L-P-L-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K"} +{"text": "### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate forming two phosphate ions ### SEQUENCE -M-S-L-N-N-V-P-A-G-K-S-L-P-D-D-L-Y-V-V-I-E-I-P-A-N-A-D-P-I-K-Y-E-V-D-K-E-S-G-A-V-F-V-D-R-F-M-S-A-P-M-F-Y-P-C-N-Y-G-Y-V-N-H-T-L-S-L-D-G-D-P-V-D-V-L-V-P-T-P-Y-P-L-M-P-G-S-V-I-R-C-R-P-V-G-V-L-K-M-T-D-E-S-G-E-D-A-K-V-V-A-V-P-H-S-K-L-S-K-E-Y-D-H-I-Q-D-V-N-D-L-P-E-L-L-K-A-Q-I-T-H-F-F-E-R-Y-K-E-L-E-S-G-K-W-V-K-V-D-G-W-E-D-V-E-A-A-R-K-E-I-L-D-S-Y-Q-R-A-Q-N-K"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-R-P-S-E-K-Q-D-N-L-V-R-A-F-K-A-L-L-K-E-E-R-F-G-S-Q-G-E-I-V-E-A-L-K-Q-E-G-F-E-N-I-N-Q-S-K-V-S-R-M-L-T-K-F-G-A-V-R-T-R-N-A-K-M-E-M-V-Y-C-L-P-T-E-L-G-V-P-T-V-S-S-S-L-R-E-L-V-L-D-V-D-H-N-Q-A-L-V-V-I-H-T-G-P-G-A-A-Q-L-I-A-R-M-L-D-S-L-G-K-S-E-G-I-L-G-V-V-A-G-D-D-T-I-F-I-T-P-T-L-T-I-T-T-E-Q-L-F-K-S-V-C-E-L-F-E-Y-A-G"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-S-E-G-Q-T-L-R-L-E-K-L-D-V-E-T-G-A-T-V-E-F-D-K-V-L-L-V-A-N-G-E-D-I-K-V-G-A-P-L-V-E-G-G-K-V-V-A-E-V-V-Q-H-G-R-G-D-K-V-K-I-V-K-F-R-R-R-K-H-S-R-K-Q-Q-G-H-R-Q-W-F-T-E-V-K-I-T-G-I-N-A"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-Q-G-F-K-Q-H-T-G-L-V-V-P-L-D-A-A-N-V-D-T-D-A-I-I-P-K-Q-F-L-Q-K-V-S-R-L-G-F-G-K-H-L-F-H-D-W-R-F-L-D-D-A-G-E-Q-P-N-P-E-F-V-M-N-H-A-R-Y-Q-G-A-S-I-L-L-A-R-E-N-F-G-C-G-S-S-R-E-H-A-P-W-A-L-A-D-Y-G-I-R-A-M-I-A-P-S-F-A-D-I-F-Y-S-N-S-I-N-N-Q-M-V-P-V-R-L-T-E-Q-E-V-D-E-L-F-Q-Y-V-Q-A-T-E-G-A-Q-I-E-V-D-L-E-A-L-K-V-R-A-N-D-K-E-Y-S-F-G-I-D-D-F-R-R-H-C-L-L-N-G-L-D-H-I-G-L-T-L-Q-H-E-D-K-I-A-A-F-E-A-D-I-P-A-F-L-R"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-V-A-K-P-E-T-V-K-R-D-W-Y-V-V-D-A-E-G-K-T-L-G-R-L-A-S-E-I-A-S-R-L-R-G-K-H-K-A-E-Y-T-P-H-V-D-T-G-D-Y-I-I-V-I-N-A-E-K-V-T-V-T-G-N-K-A-A-A-K-T-Y-Y-R-H-T-E-F-P-G-G-I-K-S-I-T-F-D-K-L-I-V-R-K-P-E-M-V-I-E-L-A-V-K-G-M-L-P-R-G-P-L-G-R-A-M-Y-R-K-L-K-V-Y-A-G-A-E-H-N-H-V-A-Q-Q-P-K-V-L-D-I"} +{"text": "### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-Q-G-I-Q-I-T-K-A-A-N-D-D-L-L-N-S-I-W-L-L-D-S-E-K-N-E-A-R-C-V-A-A-V-S-G-Y-E-A-D-Q-I-V-A-I-N-E-L-G-E-F-E-S-R-E-V-A-I-E-A-A-P-R-I-E-G-G-Q-H-L-N-V-N-V-L-K-R-E-T-L-E-D-A-V-A-H-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-A-R-T-F-T-E-S-L"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-G-D-G-Y-R-L-N-V-G-I-V-I-C-N-N-H-G-Q-V-F-W-A-K-R-Y-G-Q-H-S-W-Q-F-P-Q-G-G-I-D-D-G-E-T-P-E-Q-A-M-F-R-E-L-Y-E-E-V-G-L-T-H-K-D-V-K-I-I-A-S-S-R-H-W-L-R-Y-K-L-P-K-R-L-V-R-W-D-S-K-P-V-C-I-G-Q-K-Q-K-W-F-L-L-R-L-E-C-D-E-S-K-I-N-M-Q-K-G-S-S-P-E-F-D-G-W-R-W-V-S-Y-W-Y-P-V-R-Q-V-V-S-F-K-R-D-V-Y-R-R-A-M-K-E-F-A-S-L-A-M-P-F-R-E-R-K-L-K-G-K-K-V-K-R-R-G"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-N-K-S-A-K-K-R-A-I-Q-A-E-K-R-R-Q-H-N-A-S-R-R-S-M-M-R-T-Y-M-K-K-T-V-A-A-I-A-A-G-D-K-E-A-A-T-A-A-F-A-V-V-T-P-I-L-D-R-M-A-T-K-G-L-I-H-K-N-K-A-A-R-H-K-S-R-F-A-A-Q-I-K-A-L"} +{"text": "### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-S-Q-Q-P-E-Y-T-D-W-Q-Q-I-V-D-L-V-K-H-S-V-E-Q-K-Q-H-D-M-L-L-T-M-L-M-T-P-D-E-R-E-A-L-V-S-R-V-N-I-V-R-E-L-L-K-G-E-L-S-Q-R-Q-I-S-Q-M-L-G-V-G-I-A-T-I-T-R-G-S-N-E-L-K-L-K-S-D-E-D-K-A-R-L-N-Q-L-L-E-G-T-K-K-G-G"} +{"text": "### FUNCTION Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins ### SEQUENCE -M-K-L-T-S-K-G-R-Y-A-V-T-A-M-L-D-V-A-L-H-S-Q-K-S-P-V-P-L-A-D-I-S-E-R-Q-G-I-S-L-S-Y-L-E-Q-L-F-S-K-L-R-K-A-G-L-V-A-S-V-R-G-P-G-G-G-Y-R-L-G-A-D-A-F-T-I-S-I-G-T-V-I-A-A-V-D-E-S-V-D-A-T-K-C-Q-G-K-G-D-C-Q-G-G-T-R-C-L-T-H-T-L-W-R-D-L-S-S-R-I-T-D-F-L-N-N-I-T-L-G-E-L-M-S-D-N-E-V-I-E-I-S-D-R-Q-D-I-D-L-A-V-N-H-G-L-A-N-K-T-I-N-T-A-P-I-G-V-N-F-R-S"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-H-F-E-L-F-G-L-P-P-Q-F-S-L-D-G-S-L-L-S-S-Q-F-R-E-L-Q-K-R-F-H-P-D-N-F-A-T-A-S-E-R-D-R-L-L-A-V-Q-K-A-A-Q-I-N-D-A-Y-Q-V-L-K-N-P-I-S-R-A-E-Y-L-L-S-Q-N-G-L-E-I-R-G-E-Q-Q-T-M-Q-D-P-M-F-L-M-E-Q-M-E-L-R-E-E-L-E-E-I-P-H-G-S-D-A-E-S-A-L-A-A-F-D-A-R-V-S-K-M-Y-K-Q-H-L-A-T-I-E-Q-E-L-N-D-A-Q-W-P-Q-A-A-D-R-V-R-K-L-K-F-I-A-K-L-K-N-E-I-E-L-V-E-E-K-L-F-G"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-N-S-K-P-K-A-G-S-N-T-I-A-L-N-K-K-A-R-H-E-Y-F-I-E-D-E-I-E-A-G-M-E-L-Q-G-W-E-V-K-A-L-R-Q-G-K-A-N-I-S-E-S-Y-V-F-M-R-D-G-E-A-F-V-S-G-M-T-I-T-P-L-N-Q-A-S-T-H-V-V-A-N-P-T-R-V-R-K-L-L-M-S-R-R-E-L-D-N-L-L-G-R-I-N-R-E-G-M-T-L-A-A-L-S-L-Y-W-A-R-S-W-V-K-I-K-I-G-V-A-K-G-K-K-L-H-D-K-R-D-D-I-K-D-R-D-W-Q-R-Q-K-A-R-V-M-K-S-S-L-R"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-N-E-E-N-K-I-N-E-E-A-L-K-Q-Q-D-A-A-E-V-E-V-E-A-V-G-T-D-A-D-I-E-W-N-E-E-A-D-E-S-A-A-K-I-A-E-L-E-A-A-L-L-A-S-E-A-R-V-K-E-Q-Q-D-S-V-L-R-A-K-A-E-V-E-N-M-R-R-R-T-E-Q-E-I-D-K-A-R-K-Y-A-L-N-R-F-A-E-E-L-L-P-V-I-D-N-L-E-R-A-I-Q-A-A-D-A-E-S-E-A-V-K-P-L-L-E-G-V-E-L-T-H-K-T-F-V-D-V-V-S-K-F-G-L-K-E-I-N-P-E-G-Q-P-F-N-P-E-W-H-Q-A-M-S-I-Q-E-S-P-D-H-E-S-N-T-V-M-F-V-M-Q-K-A-M-N"} +{"text": "### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-S-E-V-T-N-N-P-T-H-N-R-L-L-A-K-L-R-A-M-G-P-Y-L-R-D-P-Q-S-K-E-G-L-Y-Y-F-D-C-L-S-V-C-I-D-D-R-K-S-P-E-L-R-E-F-W-G-W-W-M-E-L-E-A-T-E-G-G-F-T-A-N-Y-H-I-G-K-Y-D-V-E-G-N-W-L-D-L-A-I-P-K-N-A-L-E-E-V-N-K-T-Q-N-C-F-H-L-K-L-V-K-T-L-E-E-N-F-Q-L-S-V-A-Y-H-E-Q-S-V-E-F-V"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-S-E-N-D-T-K-V-I-D-S-R-L-V-A-D-G-H-Q-V-R-R-R-R-Q-C-L-A-C-N-E-R-F-T-T-F-E-T-A-E-L-L-M-P-K-V-I-K-S-N-G-N-R-E-P-F-N-E-D-K-M-V-G-G-I-Q-R-A-L-E-K-R-P-V-S-A-D-A-I-E-L-A-I-S-M-I-K-S-K-L-R-A-T-G-E-R-E-V-P-S-K-M-I-G-N-L-V-M-E-Q-L-K-D-L-D-K-V-A-Y-I-R-F-A-S-V-Y-R-S-F-E-D-I-R-E-F-G-E-E-I-A-R-L-E-D"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-V-I-E-G-G-F-P-A-P-N-A-K-I-A-I-V-I-S-R-F-N-S-F-I-N-E-S-L-L-S-G-A-I-D-T-L-K-R-H-G-Q-V-S-E-D-N-I-T-V-V-R-C-P-G-A-V-E-L-P-L-V-A-Q-R-V-A-K-T-G-K-F-D-A-I-V-S-L-G-S-V-I-R-G-G-T-P-H-F-D-Y-V-C-S-E-M-N-K-G-L-A-Q-V-S-L-E-F-S-I-P-V-A-F-G-V-L-T-V-D-T-I-D-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-A-E-A-A-L-S-A-L-E-M-I-N-V-L-S-E-I-D-S"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-G-A-S-V-K-P-A-A-R-R-N-A-R-Q-F-A-L-Q-A-I-Y-S-W-Q-I-T-K-E-N-V-A-T-I-E-A-Q-F-L-A-G-E-K-Y-D-E-E-E-H-R-A-A-E-P-A-L-A-A-P-E-T-D-V-A-Y-F-R-D-L-L-T-G-V-V-L-S-H-T-E-L-D-S-K-I-R-P-Y-V-S-R-P-M-Q-D-L-D-M-M-E-L-A-L-L-R-L-A-M-Y-E-M-T-R-R-E-D-V-P-Y-K-V-V-I-N-E-A-I-E-L-A-K-V-F-A-A-E-D-S-H-K-F-V-N-G-V-L-D-K-A-A-P-H-V-R-K-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-T-K-K-P-E-N-M-S-F-E-A-T-I-E-E-L-D-N-L-V-D-Q-L-E-N-G-D-L-A-L-D-D-A-L-K-K-F-E-R-G-I-A-L-A-R-A-S-Q-A-K-L-T-E-A-E-Q-R-V-S-I-L-L-S-D-S-D-D-A-P-L-S-D-F-S-T-L-A-E"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-Q-L-I-A-V-G-T-K-M-P-K-W-V-E-E-G-F-Q-E-Y-R-R-R-F-P-H-D-M-P-L-E-L-I-E-I-T-A-G-K-R-G-K-N-A-D-I-A-R-I-L-Q-K-E-G-E-A-M-L-A-A-I-P-K-G-N-R-I-V-T-L-D-I-P-G-K-K-W-D-T-P-E-L-A-Q-Q-L-E-A-W-K-L-D-G-R-D-V-S-I-L-I-G-G-P-E-G-L-A-P-A-C-K-A-A-A-E-Q-S-W-S-L-S-A-L-T-L-P-H-P-L-V-R-I-V-M-A-E-S-L-Y-R-A-W-S-I-T-T-N-H-P-Y-H-R-E"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-I-E-L-D-L-Q-L-A-V-E-D-Q-N-G-L-P-S-A-Q-D-F-Q-T-W-L-D-K-T-I-P-P-F-Q-P-Q-A-E-V-T-I-R-I-V-D-S-Q-E-S-H-Q-L-N-H-D-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-A-P-P-G-M-E-M-D-L-L-G-D-L-V-I-C-R-Q-V-V-E-Q-E-A-I-D-Q-D-K-P-L-M-A-H-W-A-H-M-V-V-H-G-S-L-H-L-L-G-Y-D-H-I-E-D-D-E-A-E-E-M-E-S-L-E-T-E-I-M-Q-G-M-G-F-T-D-P-Y-L-A-E-K-E"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-Q-Q-I-K-L-L-V-G-L-A-N-P-G-P-E-Y-A-K-T-R-H-N-A-G-A-W-V-V-E-E-L-A-R-V-H-N-I-T-L-K-N-E-A-K-F-Y-G-L-T-G-R-I-V-M-N-G-Q-E-L-R-L-L-I-P-T-T-F-M-N-L-S-G-K-A-I-A-A-L-A-K-F-Y-Q-I-Q-P-E-E-I-M-V-A-H-D-E-L-D-L-P-P-G-I-A-K-F-K-K-G-G-G-H-G-G-H-N-G-L-R-D-T-I-S-K-L-G-N-N-K-E-F-Y-R-L-R-I-G-I-G-H-P-G-H-K-D-K-V-A-G-F-V-L-G-K-A-P-A-S-E-Q-S-L-L-D-A-T-V-D-E-S-V-R-C-L-D-I-L-I-K-D-G-L-S-K-A-Q-N-R-L-H-T-F-K-A-E"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-L-E-F-F-R-P-Q-K-K-T-S-A-S-L-A-K-E-R-L-Q-I-I-V-A-E-R-R-S-Q-N-D-P-A-P-S-Y-L-P-Q-L-K-E-D-I-L-K-V-I-S-K-Y-V-A-I-D-P-A-M-V-D-L-T-F-E-H-K-D-D-D-I-S-V-L-E-L-N-V-K-L-P-D-E-E-K"} +{"text": "### FUNCTION Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates ### SEQUENCE -M-L-Q-T-T-L-K-Y-R-N-R-C-N-I-C-V-R-E-Y-K-C-C-I-G-S-F-M-S-R-F-G-L-S-N-M-A-L-T-H-Y-L-T-S-I-I-H-S-F-T-S-L-A-H-Q-M-L-K-R-T-N-Q-D-L-P-T-P-V-K-Y-Y-N-P-E-I-A-K-E-Y-K-K-I-E-A-A-A-E-Q-K-L-L-S-M-L-P-E-E-F-Q-E-D-F-R-P-F-V-I-S-Q-Q-T-S-E-E-E-A-Q-I-V-K-Q-A-D-S-I-C-A-Y-L-K-C-L-E-E-L-S-A-G-N-H-E-F-A-L-A-K-K-R-L-D-I-T-L-A-E-R-K-T-P-E-M-D-Y-F-L-N-T-F-A-P-S-F-E-L-S-L-D-E-I-S"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-K-S-L-I-R-D-V-P-D-F-P-K-P-G-I-L-F-R-D-L-T-T-L-L-Q-N-Q-A-G-L-R-Y-V-I-D-Q-L-V-E-K-H-A-N-A-G-I-D-Y-V-A-G-I-E-S-R-G-F-I-F-G-A-P-L-A-Y-R-L-G-A-G-F-I-P-L-R-K-P-G-K-L-C-A-P-V-Y-A-V-E-Y-E-L-E-Y-G-R-D-R-L-E-M-H-Q-D-A-I-E-P-G-R-R-V-L-I-V-D-D-L-I-A-T-G-G-T-A-A-A-A-A-G-L-I-Q-K-A-Q-A-E-L-Y-G-F-A-F-I-V-E-L-T-D-L-A-G-R-Q-K-L-P-D-V-P-I-T-T-L-V-T-Y"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-I-S-V-L-G-L-D-L-G-R-K-R-I-G-V-A-G-C-D-R-L-G-Q-L-A-T-G-I-T-T-I-Y-R-R-N-F-A-S-D-V-A-Q-L-R-R-I-C-Q-E-R-G-V-E-K-L-I-V-G-L-P-Y-T-L-D-G-Q-L-G-S-Q-A-R-Q-V-Q-H-L-A-E-K-I-G-A-A-L-N-L-P-V-E-Y-I-D-E-R-L-T-S-F-Q-A-E-E-I-L-K-Q-R-R-R-S-P-R-H-H-K-D-L-V-D-Q-I-A-A-A-L-I-L-Q-Q-W-L-D-A-R-S-Q-T-A-K-A-T-L-A-A-G-D-P-Q-L"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-T-A-M-A-G-E-V-V-E-I-L-S-A-D-D-L-R-R-T-L-T-R-L-A-S-Q-V-V-E-K-A-R-D-A-L-D-K-L-V-L-L-G-I-H-T-R-G-V-P-L-A-K-L-L-G-Q-Q-V-E-Q-L-E-G-A-S-L-P-I-G-E-L-D-I-T-F-Y-R-D-D-L-D-R-I-G-P-R-T-P-R-Q-T-L-I-P-V-D-L-S-G-R-I-V-V-L-V-D-D-V-I-F-S-G-R-T-I-R-S-A-L-N-A-V-H-D-Y-G-R-P-N-A-I-W-L-L-A-L-I-D-R-G-H-R-E-L-P-I-H-P-D-F-T-G-K-A-L-P-T-A-R-D-E-V-V-K-V-L-L-Q-G-I-D-Q-R-D-G-V-E-L-W-K-P-S"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-Q-K-R-L-H-Y-S-S-L-E-I-N-R-R-A-E-E-L-I-Q-H-S-A-N-R-Y-R-I-T-V-Q-I-A-N-R-A-K-Q-R-R-G-L-E-A-S-E-D-L-D-D-L-P-L-K-P-V-I-R-A-I-I-E-M-S-D-E-V-A-Q-P-E-L-L-A-D-S"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-N-V-A-R-K-R-R-K-K-I-L-K-L-A-K-G-Y-R-A-G-H-S-K-L-F-R-T-A-N-Q-V-V-M-K-A-L-C-N-A-Y-R-D-R-R-R-R-K-R-D-F-R-R-L-W-I-A-R-I-N-A-A-A-R-Q-Y-G-M-S-Y-S-Q-L-M-G-A-L-K-K-A-D-I-Q-L-N-R-K-M-L-A-Q-L-A-V-L-D-A-P-A-F-A-T-V-I-Q-T-A-R-A-L"} +{"text": "### FUNCTION Covalently attaches a chromophore to Cys residue of phycobiliproteins ### SEQUENCE -M-T-H-A-T-D-V-L-T-L-G-R-W-M-A-A-D-F-S-N-Q-A-Q-A-F-E-N-P-P-F-Y-A-H-I-R-V-C-M-R-P-L-P-R-G-V-L-E-G-I-A-L-Y-V-E-Q-A-Y-D-Y-L-L-S-V-P-Y-R-T-R-V-L-E-L-M-P-A-N-D-H-I-V-I-K-N-Y-V-L-K-D-E-K-R-F-F-G-A-A-R-D-R-Q-R-L-Q-A-M-T-A-D-D-L-E-L-L-C-G-C-N-M-L-T-Y-W-T-G-H-S-F-R-G-E-V-E-P-G-K-A-C-K-V-V-R-K-G-R-E-T-Y-L-D-S-T-F-E-I-D-G-D-R-F-I-S-H-D-R-G-R-D-P-E-T-D-E-H-V-W-G-S-V-A-G-P-F-H-F-V-R-W-Q-S-F-A-D-E-V-M-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-F-Y-R-R-R-I-S-P-I-P-P-G-Q-P-I-D-Y-K-D-V-D-L-L-R-R-F-I-T-E-R-G-K-I-L-P-R-R-V-T-G-L-T-A-K-Q-Q-R-Q-L-A-V-A-I-K-R-A-R-I-M-A-L-L-P-F-L-N-L-E-G"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-I-S-E-L-L-E-R-L-F-T-R-T-P-P-S-R-T-T-A-K-E-R-L-K-L-V-L-A-H-D-R-T-A-L-T-P-E-I-L-D-N-L-R-R-D-I-L-E-V-V-S-R-Y-V-E-L-E-T-E-G-L-A-V-S-L-E-S-D-Q-R-T-T-A-L-I-A-N-L-P-I-K-R-L-K-L-S-P-E-D-A-P-L-P-E-N-F-P-P-E-N-E-A-K-E-R"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-Q-I-Q-M-L-L-P-L-V-Q-T-L-A-Q-Q-V-A-D-Q-E-H-L-D-L-V-S-V-Q-W-L-T-H-Q-S-P-P-I-L-R-V-E-V-R-H-P-E-N-D-T-S-L-E-D-C-E-R-L-S-R-A-L-E-M-A-L-D-E-L-P-E-F-E-F-A-Y-V-L-E-V-S-S-P-G-L-S-D-Y-L-S-S-D-R-D-F-D-A-F-R-G-F-P-V-R-V-T-T-T-A-P-H-R-G-K-T-L-W-E-G-N-L-I-R-R-D-E-V-N-V-Y-L-N-Q-R-G-R-S-L-A-I-P-R-S-L-I-A-S-V-Q-L-Y-T-P-S-S-E-P"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-G-D-S-I-K-V-L-S-E-N-R-Q-A-R-F-Q-Y-E-I-L-E-T-Y-E-C-G-L-V-L-L-G-T-E-V-K-S-I-R-A-G-K-V-N-L-R-D-G-F-A-R-I-R-N-G-E-A-W-L-M-N-V-H-I-S-P-H-E-S-T-N-P-S-Y-N-H-D-P-L-R-D-R-K-L-L-L-H-K-Q-E-I-R-K-L-V-G-K-V-E-Q-K-G-L-T-L-V-P-L-K-L-Y-L-K-N-G-R-V-K-V-S-L-G-L-A-R-G-K-K-L-H-D-K-R-Q-D-L-K-Q-R-Q-D-K-R-E-M-E-R-A-M-K-Q-R"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-N-Q-S-E-I-L-E-K-V-K-A-I-V-A-D-Q-L-S-V-D-P-E-K-V-V-P-E-A-S-F-A-E-D-L-N-A-D-S-L-D-S-V-E-L-I-M-A-L-E-E-E-F-G-V-E-I-P-D-E-E-A-E-K-L-K-T-V-Q-D-V-L-D-F-I-N-N-K-V-A-A"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Q-C-P-Y-C-H-H-T-D-S-R-V-L-E-S-R-S-A-E-G-G-Q-S-I-R-R-R-R-E-C-L-A-C-G-R-R-F-T-T-Y-E-R-I-E-F-V-P-I-T-V-I-K-R-N-G-D-R-E-S-F-D-R-S-K-L-L-R-G-I-M-T-A-C-G-K-T-N-I-P-Q-Q-K-I-E-A-L-V-D-D-I-E-A-D-L-Q-L-R-S-R-R-E-V-T-S-A-E-L-G-E-A-A-L-Q-R-L-R-H-L-S-E-V-A-Y-V-R-F-A-S-V-Y-R-Q-F-Q-G-I-S-D-F-V-A-E-L-A-H-L-Q-E-T-P-A-S-P-E-L-L-T-I-S-Q-S"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-D-E-S-L-A-D-L-R-Q-E-L-L-A-L-L-C-R-D-A-Y-R-A-G-D-F-T-L-S-S-G-Q-K-S-Q-Y-Y-I-N-C-K-P-V-T-L-S-A-R-G-A-Y-L-V-G-R-L-F-L-E-Q-L-A-P-E-A-V-A-V-A-G-L-T-L-G-A-D-P-L-V-V-A-V-S-V-L-S-N-L-A-G-Q-D-R-A-A-L-I-V-R-K-E-A-K-G-H-G-T-M-S-F-I-E-G-P-P-L-P-Q-G-A-V-V-T-V-L-E-D-V-I-T-T-G-G-S-A-L-K-A-V-G-R-L-Q-E-A-G-Y-V-V-N-E-V-L-G-I-V-D-R-Q-G-G-G-A-A-A-F-A-A-Q-G-I-P-L-R-S-L-F-Q-I-S-D-L-E-A-Y-L-N-R-T"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-E-R-E-K-K-R-Q-R-L-V-A-K-Y-A-S-K-R-Q-E-L-K-A-Q-L-A-S-A-E-T-Q-E-E-I-M-S-I-H-R-Q-L-Q-R-L-P-R-N-S-A-P-S-R-L-R-N-R-C-W-L-T-G-R-P-R-G-Y-Y-R-D-F-G-L-C-R-N-A-L-R-E-M-A-H-Q-G-L-L-P-G-V-V-K-S-S-W"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-P-T-L-T-D-S-P-P-T-T-V-L-T-V-T-E-L-Q-Q-L-L-P-H-R-Y-P-F-L-L-V-D-R-I-I-D-Y-V-P-E-K-Y-A-V-G-L-K-N-V-T-I-N-E-P-F-F-Q-G-H-F-P-G-R-P-I-M-P-G-V-L-I-V-E-A-L-A-Q-V-G-G-V-V-L-M-Q-M-N-W-A-K-D-K-L-S-V-F-A-G-I-D-K-V-R-F-R-R-P-V-V-P-G-D-Q-L-I-L-R-A-E-L-L-V-V-K-Q-Q-R-I-G-K-M-Q-G-R-A-E-V-N-G-Q-L-V-C-E-G-E-M-M-F-S-L-V-D"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-A-L-Q-Q-K-I-R-I-R-L-K-A-F-D-H-R-L-L-D-T-S-C-D-R-I-V-D-T-A-K-R-T-G-A-S-P-V-G-P-I-P-L-P-T-R-R-R-I-Y-C-V-L-R-S-P-H-V-D-K-D-S-R-E-H-F-E-T-R-T-H-C-R-I-L-D-I-Y-Q-P-S-P-K-T-I-D-A-L-I-K-L-D-L-P-A-G-V-D-I-E-V-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-T-R-A-Q-K-R-P-T-A-P-D-P-V-Y-N-N-V-L-V-N-M-L-I-Q-R-V-M-R-N-G-K-K-S-L-A-S-R-I-V-Y-E-A-M-K-T-V-Q-E-R-T-G-E-D-A-L-Q-I-F-E-R-A-V-K-N-A-T-P-L-V-E-V-K-A-R-R-V-G-G-A-T-Y-Q-V-P-M-E-V-R-P-D-R-G-I-S-L-A-L-R-W-L-V-Q-F-S-R-K-R-A-G-R-S-M-S-A-K-L-A-N-E-L-M-D-A-A-N-E-T-G-S-T-I-R-K-R-E-E-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-Y"} +{"text": "### FUNCTION Covalently attaches a chromophore to Cys residue of phycobiliproteins ### SEQUENCE -M-C-I-G-M-D-I-R-D-F-F-A-Q-S-A-G-R-W-F-S-Q-R-T-S-H-H-L-A-F-K-Q-T-E-S-G-K-S-Q-L-T-I-E-L-L-S-V-D-D-P-A-V-I-A-L-C-Q-Q-Y-D-M-D-P-A-W-A-V-C-G-A-R-V-S-W-D-G-T-M-E-W-D-N-E-K-H-E-G-S-T-V-L-V-P-I-M-D-Q-G-S-R-M-E-G-K-L-L-R-E-M-G-Y-A-E-K-A-P-V-A-G-R-F-S-M-G-S-D-G-A-L-T-L-I-T-E-Y-E-T-I-Y-S-E-E-R-L-W-F-A-S-P-N-L-R-L-R-T-S-I-L-K-R-F-G-G-F-S-M-A-S-F-C-S-E-I-R-L-G-V-T-Q-P-A-N-S"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-T-L-T-Y-P-E-D-L-Q-Y-L-D-S-H-E-Y-L-R-L-E-G-D-T-A-T-L-G-I-S-A-F-A-V-D-Q-L-G-D-I-V-F-V-E-L-P-A-V-G-D-A-L-E-P-G-E-R-F-G-T-I-E-S-V-K-A-V-E-D-L-Y-A-P-L-G-G-T-V-I-A-V-N-Q-A-V-I-D-N-P-E-Q-I-A-A-D-P-Y-G-E-G-W-L-V-K-V-Q-V-S-T-L-P-T-G-L-L-S-A-A-D-Y-R-A-L-V-E-G-S"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-A-S-L-A-V-E-K-K-K-L-K-N-P-P-L-Q-L-H-Y-L-G-D-R-V-L-R-Q-P-A-K-R-V-S-K-V-D-D-S-I-R-D-I-A-R-K-M-L-Q-T-M-Y-S-A-D-G-I-G-L-A-A-P-Q-V-G-I-N-K-Q-I-L-V-I-D-I-H-P-D-D-P-E-A-E-P-L-V-M-I-N-P-V-I-K-D-F-S-E-E-L-E-V-C-Q-E-G-C-L-S-I-P-G-V-Y-L-E-V-R-R-P-A-M-V-E-V-S-Y-K-D-E-W-G-R-P-Q-V-I-M-A-G-G-L-L-A-R-A-I-Q-H-E-I-D-H-L-T-G-V-M-F-V-D-R-V-E-N-Q-A-L-L-R-H-E-L-K-E-H-G-F-T-A-S-A-V-R-P-I-A-A"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-T-E-R-R-V-A-R-V-A-E-L-I-K-R-E-V-S-Q-L-L-M-Y-E-I-R-D-E-R-V-G-A-G-M-V-S-V-T-D-V-E-V-S-G-D-L-Q-H-A-K-I-F-V-S-I-Y-S-T-E-E-V-R-R-S-T-M-A-G-L-K-A-A-S-G-F-V-R-R-E-L-G-Q-R-I-R-L-R-R-T-P-E-V-V-F-I-E-D-R-S-L-E-R-G-S-R-V-L-A-L-L-N-Q-I-G-Q-Q-Q-S-T-S-E-V-L-E-S"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-T-V-Q-V-A-V-A-L-T-K-K-T-Q-Q-E-Q-P-M-I-N-E-R-I-H-F-P-R-V-R-V-V-D-T-D-G-S-Q-L-G-I-M-S-S-Q-E-A-I-A-I-A-R-E-K-E-L-D-L-V-L-V-S-D-K-A-D-P-P-V-C-K-I-I-D-Y-G-K-F-R-F-E-Q-E-K-K-A-R-E-A-R-K-K-Q-H-T-S-D-V-K-E-V-K-M-R-Y-K-I-E-E-H-D-Y-N-V-C-I-N-R-A-E-R-F-L-K-A-G-D-K-V-K-A-T-V-T-F-R-G-R-E-I-Q-H-S-H-L-A-E-E-L-L-N-R-M-A-N-D-L-Q-A-V-A-E-V-Q-Q-A-P-K-Q-E-G-R-N-M-I-M-F-L-A-P-K-R"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-V-T-V-Y-L-E-V-H-D-P-A-L-P-A-E-V-T-A-L-P-W-E-R-W-F-R-T-W-M-A-M-V-E-P-T-Q-G-K-V-Y-E-L-T-L-R-L-T-T-D-A-A-I-Q-A-L-N-Q-Q-Y-R-D-R-D-T-P-T-D-V-L-A-F-A-T-R-D-G-A-L-P-L-P-L-G-E-P-E-Y-L-G-D-I-I-I-S-G-D-T-A-R-R-Q-A-A-E-S-G-H-T-L-S-I-E-I-A-W-L-A-C-H-G-L-L-H-L-L-G-W-D-H-P-D-E-A-E-L-A-R-M-L-T-Q-Q-A-Q-C-L-E-A-V-G-L-T-P-P-A-A-L-Q"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-Q-R-N-D-N-F-I-D-K-T-F-T-V-M-A-D-L-I-L-K-V-L-P-T-S-S-Q-S-K-T-A-F-A-Y-Y-R-D-G-M-S-A-Q-A-D-G-E-Y-A-E-A-L-E-N-Y-Q-A-A-L-E-L-E-E-D-P-T-D-R-S-Y-I-L-Y-N-I-G-L-I-H-A-S-N-G-E-H-E-K-A-L-E-Y-Y-H-Q-A-L-E-L-N-P-R-M-P-Q-A-L-N-N-I-A-V-I-Y-H-Y-L-G-T-Q-A-E-E-Q-Q-R-L-E-E-A-E-Q-F-F-D-R-A-A-D-Y-W-K-R-A-I-Q-L-A-P-N-N-Y-I-E-A-Q-N-W-L-K-T-T-G-R-S-N-I-D-V-Y-F"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-T-T-K-V-I-T-A-E-D-V-R-K-V-A-H-L-A-R-L-A-I-D-E-S-E-I-E-A-L-T-Q-Q-L-D-S-I-L-D-Y-V-N-Q-L-S-E-L-D-V-T-E-V-P-P-T-T-R-A-I-E-V-S-N-V-T-R-P-D-V-L-A-P-W-P-N-R-E-D-L-L-A-I-A-P-E-R-E-D-D-F-F-R-V-P-K-I-M"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-A-E-E-I-F-N-T-A-V-I-T-F-T-L-V-L-V-G-L-G-A-G-Y-L-L-L-R-L-T-P-D-D"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-T-N-S-P-I-T-E-P-S-P-R-Q-E-S-V-L-R-Y-P-V-L-G-S-R-R-P-S-N-Y-F-W-A-T-A-V-S-I-G-G-L-G-F-F-L-A-G-L-S-S-Y-L-H-R-N-L-L-P-I-G-N-P-I-D-L-V-F-I-P-Q-G-I-A-I-G-F-Y-G-V-A-A-L-L-L-A-T-Y-L-W-L-A-I-A-W-D-V-G-G-G-F-N-E-F-N-K-E-T-G-F-V-R-I-F-R-W-G-F-P-G-K-N-R-Q-I-E-V-S-C-P-I-S-D-V-Q-A-V-K-I-V-I-K-E-G-L-N-P-K-R-S-L-Y-L-K-I-K-G-R-G-E-V-P-L-T-R-V-G-A-P-L-P-L-A-E-L-E-T-Q-G-A-T-I-A-S-F-L-G-V-P-V-E-G-L"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-P-A-T-V-L-S-I-A-L-A-A-V-C-I-G-V-T-G-Y-S-I-Y-L-S-F-G-P-P-S-K-E-L-A-D-P-F-D-D-H-E-D"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-N-V-F-G-I-G-L-P-E-L-I-V-I-L-V-V-A-L-L-I-F-G-P-K-K-L-P-E-I-G-R-S-L-G-K-T-K-R-A-F-E-E-A-S-R-E-F-Q-D-E-I-K-R-Q-T-A-A-L-E-E-E-Q-Q-A-K-A-E-A-E-S-P-R-E-I-S-P"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-F-T-L-T-Q-L-C-P-T-P-L-E-N-A-R-Q-L-H-L-S-L-T-A-E-E-R-C-R-R-R-L-H-C-H-S-D-E-G-E-S-L-Y-L-K-L-P-R-G-I-T-L-Q-P-G-D-R-L-R-D-E-D-A-T-V-I-V-T-V-H-A-K-P-E-P-T-L-K-V-M-A-S-T-P-L-D-L-L-R-A-A-Y-H-L-G-N-R-H-V-P-L-E-I-H-T-D-Y-L-R-L-G-A-D-S-V-V-Q-T-M-L-E-Q-R-G-L-T-V-T-F-E-V-A-P-F-C-P-E-R-G-A-Y-H-A-H"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-A-Q-D-I-I-R-S-I-E-A-E-Q-M-K-T-D-L-P-V-I-Y-V-G-D-R-V-R-V-G-V-K-I-K-E-G-D-K-E-R-V-Q-P-Y-E-G-D-V-I-A-M-R-N-T-G-I-N-R-T-I-T-V-R-R-V-F-Q-G-V-G-V-E-R-V-F-L-L-H-S-P-R-I-D-S-I-K-V-I-Q-R-G-K-V-R-R-A-K-L-Y-Y-L-R-D-R-M-G-K-A-S-R-I-K-P-R-F-D-R-P-L"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-V-P-F-V-L-A-S-A-S-P-A-R-R-Q-L-L-Q-Q-I-G-I-D-P-I-I-Q-P-S-H-F-D-E-S-V-I-Q-A-A-T-P-T-E-L-V-R-L-L-A-R-C-K-A-E-T-V-A-Q-S-Y-S-A-P-A-L-I-L-G-C-D-S-V-L-V-L-G-G-E-I-Y-G-K-P-A-S-P-E-M-A-I-A-R-W-Q-Q-M-R-G-Q-T-A-D-L-L-T-G-H-A-L-I-D-L-A-Q-G-R-T-C-V-E-V-E-S-T-Q-V-V-F-A-Q-V-S-D-A-E-I-A-A-Y-V-A-S-G-E-P-L-A-C-A-G-C-F-A-L-D-G-Q-G-G-A-F-V-E-K-I-V-G-T-P-S-N-V-I-G-L-S-L-P-L-L-R-R-L-L-L-S-L-G-Y-T-L-A-D-V-Q-N-K-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-S-N-D-F-R-P-G-V-S-I-E-L-D-G-A-V-W-R-V-V-E-F-L-H-V-K-P-G-K-G-S-A-F-V-R-T-K-L-K-N-V-Q-T-G-N-V-I-E-R-T-F-R-A-G-E-T-V-P-Q-A-T-L-E-K-R-T-M-Q-H-T-Y-K-D-G-E-D-Y-V-F-M-D-M-E-S-Y-E-E-A-R-L-T-P-A-Q-V-G-D-R-A-K-Y-L-K-E-G-M-E-V-N-I-V-K-W-G-E-Q-V-L-E-V-E-L-P-N-S-V-V-L-E-V-V-Q-T-D-P-G-V-K-G-D-T-A-T-G-G-S-K-P-A-I-V-E-T-G-A-Q-V-M-V-P-L-F-I-S-V-G-E-R-I-R-I-D-T-R-S-D-T-Y-L-G-R-E"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-I-T-R-N-Y-E-T-L-Y-I-I-R-P-D-V-G-E-E-Q-L-E-Q-T-I-S-Q-F-R-T-F-L-E-E-Q-G-A-T-K-L-K-V-Q-N-R-G-K-R-R-F-A-Y-P-I-K-K-L-R-E-G-Y-Y-I-L-M-T-Y-T-A-P-G-T-A-I-A-P-L-E-R-A-M-R-L-N-E-N-I-L-R-F-M-T-I-V-L-E-E-E-T-E-T-E-D-A-E-E-E-N-P-V-L-A-R-A"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-L-G-K-L-R-D-L-M-G-L-T-P-E-T-D-I-Y-D-E-E-Y-P-Q-G-T-A-R-T-L-T-T-E-P-G-V-E-P-L-P-A-S-P-P-T-P-T-H-D-F-D-T-R-P-S-P-S-V-A-T-G-S-V-P-T-G-S-T-A-S-N-V-I-G-M-P-N-A-G-R-W-W-G-A-V-A-E-V-L-V-M-Q-P-R-S-F-S-E-M-P-E-V-I-K-A-L-K-E-R-K-S-V-V-L-N-L-T-L-M-E-P-E-Q-A-Q-R-S-V-D-F-V-A-G-A-T-F-T-I-D-G-H-Q-E-R-I-G-E-S-I-F-L-F-T-P-S-C-V-Q-V-S-T-Q-V-G-G-V-R-P-S-A-T-P-T-P-T-P-P-S-A-W-G-M-D-A-Q-Q-H-H-S-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-A-K-R-A-Q-I-A-E-R-N-R-L-R-N-K-A-Y-R-S-A-V-R-T-L-I-K-N-Y-L-N-A-I-S-Q-Y-S-T-D-P-T-P-E-K-L-A-E-V-H-H-R-L-N-L-A-F-S-K-I-D-K-A-V-K-R-G-V-L-H-R-N-T-G-A-R-R-K-A-R-L-T-R-I-L-N-K-T-L-Q-P-A-A"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-P-S-V-V-P-Q-E-R-Q-Q-V-T-R-K-H-Y-P-N-Y-K-V-I-V-L-N-D-D-F-N-T-F-Q-H-V-A-A-C-L-M-K-Y-I-P-N-M-T-S-D-R-A-W-E-L-T-N-Q-V-H-Y-E-G-Q-A-I-V-W-V-G-P-Q-E-Q-A-E-L-Y-H-E-Q-L-L-R-A-G-L-T-M-A-P-L-E-P-E"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-P-I-G-V-P-K-V-P-Y-R-L-P-G-E-P-Y-T-Q-W-I-D-I-Y-N-R-L-Y-R-E-R-I-I-F-L-G-K-E-V-D-D-E-I-A-N-Q-I-V-A-V-M-L-Y-L-D-S-E-D-P-G-K-D-I-M-L-Y-I-N-S-P-G-G-S-V-T-A-G-M-A-I-Y-D-T-M-Q-H-I-K-S-D-V-V-T-I-C-V-G-L-A-A-S-M-G-S-F-L-L-A-A-G-T-K-G-K-R-L-A-L-P-H-S-R-I-M-I-H-Q-P-S-G-G-T-R-G-Q-A-T-D-I-E-I-E-A-R-E-I-L-R-V-R-R-Q-L-N-E-L-Y-A-Y-H-T-G-Q-P-L-E-K-I-E-R-D-M-D-R-D-F-F-M-S-A-E-E-A-K-N-Y-G-L-I-D-R-V-I-E-E-R-S-N"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-V-T-P-F-P-E-V-S-E-W-L-C-I-G-Q-I-V-G-A-H-G-L-R-G-E-V-K-V-K-P-F-S-D-F-P-E-R-F-T-V-P-G-C-R-W-L-R-S-P-R-Q-P-Q-P-Y-A-V-T-L-L-R-G-R-F-L-P-R-A-E-Q-F-V-V-T-F-A-E-I-S-D-R-T-A-A-E-A-L-K-G-A-E-I-L-V-P-A-S-D-R-P-P-L-A-A-N-E-Y-H-L-M-D-L-I-G-L-A-V-Y-H-Q-G-E-R-V-G-E-V-V-G-L-V-N-A-G-N-D-L-L-E-V-Q-L-L-D-P-A-P-K-A-P-Q-S-V-Y-I-P-F-V-P-A-I-V-P-V-V-D-L-A-A-R-R-I-E-I-D-P-P-L-G-L-L-P"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-I-E-P-L-L-C-G-I-V-L-G-L-I-P-V-T-L-A-G-L-F-F-A-A-Y-Q-Q-Y-K-R-G-S-Q-L-E-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-I-I-T-L-G-W-V-G-V-L-S-V-F-T-L-S-I-A-F-V-V-W-G-R-H-G-M"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-Q-G-Q-G-F-G-F-G-L-G-K-M-K-E-L-A-A-A-I-Q-K-A-Q-Q-V-Q-E-G-A-K-K-L-Q-E-D-L-E-R-M-D-I-E-G-Q-A-A-G-G-A-V-K-V-I-M-S-G-T-Q-E-P-R-R-V-E-I-S-P-D-L-L-S-E-G-A-E-V-L-S-D-L-V-T-A-A-M-R-D-A-Y-Q-K-S-T-A-T-M-R-E-R-M-E-E-L-T-G-S-L-N-V-P-G-L-G"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-S-R-S-L-A-I-E-G-Q-L-R-P-A-D-A-K-P-N-A-L-R-R-N-G-K-I-P-A-V-L-Y-G-P-T-I-E-S-S-I-S-L-V-V-D-T-R-A-A-E-L-L-V-R-D-A-R-P-Q-K-T-P-I-Q-L-S-I-P-D-L-P-W-Q-G-T-V-V-L-Q-E-V-Q-A-H-P-A-K-D-T-L-Y-H-L-S-F-L-A-K-A-E-N"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA biosynthesis ### SEQUENCE -M-N-P-T-P-L-R-D-Y-Q-R-T-V-H-F-A-D-T-D-A-A-G-V-V-Y-F-A-N-L-L-R-F-C-H-E-A-Y-E-D-A-L-A-Q-L-G-V-D-L-R-Q-F-F-S-N-S-G-L-I-V-P-I-T-E-A-Q-I-R-F-L-K-P-L-Y-C-G-D-R-L-R-V-T-I-D-P-Q-R-L-D-T-S-R-F-Q-L-T-Y-T-L-Y-N-E-G-G-D-R-V-A-I-A-Q-T-Q-H-M-C-L-Q-L-P-H-R-Q-R-V-P-I-P-D-P-L-P-A-W-L-K-S-A-P-E-E-A-S-D-R-E-D"} +{"text": "### FUNCTION Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 ### SEQUENCE -M-L-D-F-G-E-L-L-P-L-Q-P-P-T-I-P-A-H-Q-L-P-P-A-A-L-A-Y-F-G-D-A-V-Y-E-L-F-I-R-L-L-F-L-T-P-P-Q-R-I-N-A-Y-H-R-Q-V-V-A-H-V-R-A-E-S-Q-A-R-Y-M-D-F-L-W-E-Y-C-T-E-T-E-R-S-I-F-R-Q-G-R-N-A-A-A-D-G-P-K-R-V-A-A-K-I-Y-R-Q-A-T-G-F-E-A-L-L-G-Y-L-Y-L-T-N-P-Q-R-L-Q-E-I-F-Q-L-L-A-G-H-I-R-S-E-V-E-N-K-T-H-A-A-E-S-P-S-E-M"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-A-A-T-D-E-I-L-E-K-L-K-S-L-T-L-L-E-A-A-E-L-V-K-Q-I-E-E-T-F-G-V-S-A-A-A-P-V-G-G-M-M-V-A-A-P-V-A-G-A-A-A-A-P-A-E-E-V-E-E-K-T-A-F-D-V-I-L-E-E-V-P-A-D-K-K-I-A-V-L-K-V-V-R-S-L-T-G-L-G-L-K-E-A-K-E-V-V-E-S-T-P-K-P-V-K-E-G-A-S-K-E-D-A-E-A-A-K-K-E-L-E-E-A-G-A-K-V-S-I-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-M-R-V-G-R-T-L-A-N-K-K-E-I-V-A-E-L-K-E-R-L-R-E-S-Q-M-A-L-V-I-D-Y-Q-G-L-S-D-A-E-M-K-D-L-R-Q-R-L-R-K-C-N-A-S-C-K-V-T-K-N-T-L-M-E-L-A-V-K-E-S-D-T-W-Q-P-I-T-Q-F-L-K-G-P-S-A-F-L-L-L-K-D-D-I-G-G-A-I-K-A-Y-Q-E-F-Q-K-A-T-K-K-T-T-L-R-G-G-V-M-E-G-R-A-L-D-E-A-Q-V-K-A-I-G-D-L-P-S-K-E-Q-L-M-A-Q-I-A-G-A-L-N-A-V-T-A-K-I-A-I-G-I-K-E-V-P-A-S-L-A-R-A-T-Q-A-I-A-D-K-G-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-V-A-V-I-K-L-A-I-Q-A-G-K-A-N-P-A-P-P-I-G-P-A-L-G-Q-H-G-V-N-I-M-M-F-C-K-E-Y-N-A-R-T-A-D-Q-V-G-M-V-V-P-V-E-I-S-V-Y-E-D-R-S-F-T-F-V-L-K-T-P-P-A-S-V-L-I-Q-K-A-A-G-I-E-K-G-S-G-E-P-N-K-K-K-V-G-S-I-T-R-A-Q-L-R-E-I-A-E-K-K-M-P-D-L-N-A-N-D-I-E-A-A-M-R-I-I-E-G-T-A-R-N-M-G-V-T-I-T-D"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-K-L-A-D-V-E-E-R-M-Q-K-S-V-E-A-T-Q-H-D-F-N-S-I-R-T-G-R-A-N-A-A-L-L-D-R-V-M-V-D-Y-Y-G-T-E-T-P-L-R-S-L-A-N-V-S-T-P-D-A-T-T-I-L-I-Q-P-Y-D-R-S-T-L-A-S-I-E-K-A-I-Q-L-S-D-L-G-L-T-P-N-N-D-G-S-S-V-R-L-N-I-P-P-L-T-T-E-R-R-K-E-L-V-K-T-A-A-K-I-A-E-G-G-K-V-A-I-R-N-I-R-R-D-A-I-D-H-I-K-K-A-G-K-A-G-E-L-T-E-D-E-V-K-D-L-Q-E-K-V-Q-K-L-T-D-K-Y-I-G-K-I-D-A-L-L-A-E-K-E-K-D-I-M-T-V"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-A-Y-A-I-I-E-T-G-G-K-Q-L-R-V-E-P-G-R-F-Y-D-V-E-R-L-P-I-E-P-E-G-T-I-D-L-E-Q-V-L-L-V-Q-T-D-S-Q-V-H-V-G-Q-P-Y-V-S-G-A-V-V-S-G-T-V-M-E-H-R-R-G-P-K-V-I-V-Y-K-M-R-P-K-K-K-T-R-R-K-K-G-H-R-Q-E-L-T-R-I-M-I-N-E-I-R-L-N-G-E-S-L-G-G"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-P-K-P-N-I-H-P-Q-W-Y-P-E-A-K-V-Y-C-D-G-E-V-I-M-T-V-G-S-T-K-P-E-L-H-V-D-I-W-S-G-N-H-P-F-F-T-G-T-Q-K-I-V-D-A-E-G-R-V-E-R-F-R-R-K-Y-S-G-T-K-P-Q-Q-T-A-K-G-K-K-A-A-P-K-S-T-P-K-T-N-K-K-G"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-T-S-T-V-K-T-P-L-P-A-V-D-D-L-A-P-Q-W-Y-V-I-D-A-A-D-Q-R-L-G-R-L-A-A-E-I-A-R-I-L-R-G-K-N-K-A-I-Y-T-P-H-M-D-T-G-D-F-V-I-V-I-N-A-E-K-V-T-V-T-G-K-K-R-S-Q-K-L-Y-R-R-H-S-G-R-P-G-G-M-K-I-E-T-F-D-Q-L-Q-A-R-I-P-E-R-I-I-E-H-A-V-K-G-M-L-P-K-N-S-L-G-R-K-L-F-T-K-L-K-V-Y-A-G-P-E-H-P-H-Q-A-Q-K-P-Q-P-L-T-I-N-T-I-P-G-A"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-L-P-R-D-K-R-I-E-I-A-L-T-Y-I-Y-G-I-G-L-T-R-S-K-E-I-L-A-K-T-G-V-N-P-D-T-R-T-R-D-L-T-D-A-D-I-A-A-L-R-A-A-I-D-E-Y-Q-V-E-G-D-L-R-R-L-E-A-M-N-I-K-R-L-M-D-I-G-C-Y-R-G-R-R-H-R-L-G-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-R-G-S-R-R-T-V-A-G-K-K-K-P-A-A-K-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-Q-D-A-I-E-I-E-G-T-V-T-E-S-L-P-N-A-M-F-R-V-D-L-D-N-G-F-N-V-L-A-H-I-S-G-K-I-R-R-N-Y-I-K-I-L-P-G-D-R-V-K-V-E-L-T-P-Y-D-L-T-K-G-R-I-T-Y-R-L-R-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-F-Q-D-L-H-P-Q-A-G-S-R-R-R-K-R-R-I-G-R-G-I-A-A-G-Q-G-A-S-G-G-F-G-M-R-G-Q-K-S-R-S-G-R-P-T-R-P-G-F-E-G-G-Q-N-P-L-Y-R-R-L-P-K-L-K-H-F-P-L-V-K-R-K-V-Y-T-T-I-N-V-G-R-L-N-T-L-P-A-N-S-V-V-T-V-Q-S-L-L-E-A-G-I-L-T-T-A-K-Y-P-L-K-V-L-G-D-G-E-L-N-V-K-L-E-V-H-A-A-A-F-S-G-S-A-R-S-K-I-E-A-A-G-G-V-C-V-E-T-S-V-A-A-D-S-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-K-Q-T-R-T-A-A-R-Q-S-R-H-Q-R-I-R-R-K-V-K-G-T-S-D-R-P-R-L-A-V-F-R-S-H-Q-H-I-Y-A-Q-V-I-D-D-T-R-H-H-T-L-V-A-A-S-S-L-E-P-E-L-R-Q-K-L-G-K-G-S-T-C-A-A-S-I-A-V-G-R-L-I-A-E-R-A-K-A-A-G-I-E-R-V-V-F-D-R-G-G-N-I-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-G-G-L-D-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-R-P-I-P-L-P-K-N-V-T-L-T-L-D-G-Q-Q-V-T-V-K-G-P-K-G-Q-L-S-R-V-F-P-P-E-V-N-V-V-Q-E-G-E-A-I-V-V-K-R-R-D-D-S-R-P-A-K-E-R-H-G-L-C-R-T-L-L-A-N-M-V-E-G-V-S-Q-G-F-T-K-K-L-E-I-Q-G-V-G-Y-R-A-Q-L-Q-G-K-T-L-V-L-S-M-G-Y-S-H-P-V-E-I-V-P-P-E-G-I-T-L-E-I-E-D-N-Q-G-K-K-V-Q-Q-G-T-I-V-L-V-S-G-I-D-K-E-L-V-G-N-T-S-A-R-I-R-A-V-R-P-P-E-P-Y-K-G-K-G-I-R-Y-M-G-E-F-V-R-R-K-V-G-K-T-G-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-A-V-N-D-T-I-G-D-M-L-T-R-I-R-N-A-N-L-A-R-H-Q-T-T-T-I-P-A-T-R-M-T-R-S-I-A-Q-V-L-K-A-E-G-F-I-R-D-F-E-E-Q-G-D-G-V-K-R-H-L-V-V-S-L-K-Y-R-G-K-Q-R-Q-P-I-I-T-A-L-K-R-V-S-K-P-G-L-R-V-Y-A-N-S-R-E-L-P-R-V-L-G-G-I-G-I-A-I-I-S-T-S-N-G-I-M-T-D-R-E-A-R-K-Q-G-I-G-G-E-V-L-C-Y-V-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-Q-R-L-K-D-H-Y-N-K-T-V-V-P-Q-L-M-Q-Q-F-Q-Y-K-N-I-H-Q-V-P-K-I-V-K-V-T-V-N-R-G-L-G-E-A-A-Q-N-A-K-A-L-E-A-T-L-A-E-I-A-T-I-T-G-Q-K-P-V-V-T-R-A-K-K-A-I-A-G-F-K-I-R-K-G-M-P-V-G-V-A-V-T-L-R-S-E-R-M-Y-A-F-L-D-R-L-I-N-L-A-L-P-R-I-R-D-F-R-G-V-N-P-K-S-F-D-G-R-G-N-Y-T-L-G-L-R-E-Q-L-I-F-P-E-V-N-Y-D-D-I-D-Q-I-R-G-M-D-V-S-I-I-T-T-A-N-T-D-E-E-G-R-A-L-L-K-A-M-G-M-P-F-R-E-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-K-A-N-K-K-P-V-R-Y-R-M-H-V-K-K-G-D-T-V-Q-V-I-A-G-S-D-K-A-K-V-G-E-V-L-A-V-F-P-K-T-S-Q-V-I-V-K-G-V-N-L-K-T-K-H-L-K-P-R-Q-E-G-E-S-G-Q-I-I-T-K-E-A-P-I-H-S-C-K-V-M-L-Y-S-T-K-Q-N-V-A-S-R-I-C-Y-T-Y-T-E-D-G-R-K-V-R-M-L-K-K-T-G-E-I-I-D"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-Y-L-N-V-A-D-N-S-G-A-K-K-L-L-C-I-R-V-L-G-G-S-N-R-R-Y-G-S-V-G-D-V-I-I-A-T-V-K-D-A-T-P-N-M-A-V-K-K-S-D-V-V-R-A-V-I-V-R-T-R-K-S-I-R-R-E-S-G-M-S-I-R-F-D-D-N-A-A-V-L-I-N-Q-D-G-N-P-R-G-T-R-V-F-G-P-V-A-R-E-L-R-D-K-N-F-T-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-V-K-E-R-V-G-V-V-V-S-D-K-M-Q-K-T-V-V-V-A-V-E-N-R-A-P-H-P-K-Y-G-K-I-V-V-K-T-R-R-Y-K-A-H-D-E-N-N-E-A-K-V-G-D-R-V-R-I-R-E-T-R-P-L-S-R-T-K-R-W-V-I-A-E-I-L-S-P-R-T-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-S-P-K-R-T-K-F-R-K-Q-Q-R-G-R-M-T-G-V-A-S-R-G-N-S-I-H-F-G-D-Y-A-L-Q-A-L-E-P-A-W-I-T-A-R-Q-I-E-A-G-R-R-A-M-T-R-Y-I-R-R-G-G-K-I-W-I-R-I-F-P-D-K-P-V-T-M-R-P-A-E-T-R-M-G-S-G-K-G-S-P-E-Y-W-V-A-V-V-K-P-G-R-I-M-Y-E-I-A-G-V-T-E-E-V-A-R-E-A-M-R-L-A-A-Y-K-M-P-I-K-T-R-F-L-V-R-N-Q-E-E-Q-Q-Q-E-G"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-V-S-T-S-S-P-T-A-R-A-C-A-K-Y-V-R-M-S-P-H-K-V-R-R-V-L-D-Q-L-R-G-R-T-Y-R-D-A-L-I-M-L-R-F-M-P-Y-R-A-C-E-P-I-T-K-V-L-R-S-A-A-A-N-A-T-H-N-L-G-L-D-P-A-T-L-V-I-S-Q-A-Y-A-D-Q-G-P-C-L-K-R-F-R-P-R-A-Q-G-R-A-Y-Q-I-R-K-P-T-C-H-I-T-I-A-V-A-P-Q-N-T-A-D-E-S"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-V-A-D-H-L-L-R-K-I-E-A-L-N-E-R-N-A-K-E-V-I-K-T-W-S-R-A-S-T-I-V-P-E-M-I-G-H-T-I-A-V-H-N-G-K-Q-H-V-P-V-Y-I-T-E-Q-M-V-G-H-K-L-G-E-F-A-P-T-R-N-F-R-S-H-V-K-G-D-K-K-A-R-H"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-K-V-Q-P-R-A-L-A-D-L-I-K-R-P-I-I-T-E-K-A-T-V-L-L-E-N-N-Q-Y-T-F-D-V-D-R-R-A-T-K-P-Q-I-K-A-A-I-E-E-L-F-N-V-K-V-T-A-V-N-T-Y-H-L-P-P-K-E-R-R-V-G-R-F-V-G-R-R-P-R-Y-K-R-A-I-V-T-L-A-P-D-S-K-I-V-L-F-P-E-V"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-A-V-F-E-G-T-Y-Q-V-L-G-T-P-R-F-G-I-V-I-S-R-F-N-D-L-I-T-T-K-L-L-E-G-C-Q-D-C-L-R-R-H-G-V-D-P-N-P-H-G-S-Q-V-D-Y-A-W-V-P-G-S-F-E-I-P-L-V-A-A-Q-L-A-A-T-R-R-Y-A-A-I-I-C-L-G-A-V-I-R-G-Q-T-P-H-F-D-Y-V-A-A-E-V-T-K-G-I-A-T-A-S-M-Q-T-G-V-P-I-I-Y-G-I-L-T-T-D-T-M-Q-Q-A-L-E-R-A-G-I-K-S-N-K-G-W-E-Y-A-L-N-A-L-E-M-A-N-L-M-Q-T-L-P-S-A-I-N-P-P-T-T-K-L-S-S-S-T-R-I-L-T-D-G"} +{"text": "### FUNCTION Facilitates the functional incorporation of the urease nickel metallocenter This process requires GTP hydrolysis, probably effectuated by UreG ### SEQUENCE -M-E-T-V-L-R-V-G-V-A-G-P-V-G-S-G-K-T-A-L-V-D-A-L-C-K-A-L-R-D-R-Y-R-L-A-V-V-T-N-D-I-Y-T-Q-E-D-A-Q-F-L-V-R-S-Q-A-L-P-P-E-R-I-L-G-V-E-T-G-G-C-P-H-T-A-I-R-E-D-A-S-L-N-L-A-A-I-Q-Q-L-E-T-A-F-R-P-L-D-L-I-F-V-E-S-G-G-D-N-L-A-A-T-F-S-P-E-L-V-D-L-T-I-Y-V-I-D-V-A-A-G-D-K-I-P-R-K-G-G-P-G-I-T-K-S-D-L-L-V-I-N-K-I-D-L-A-P-Y-V-G-A-D-L-E-V-M-K-R-D-T-L-K-M-R-G-D-R-P-Y-V-M-T-N-L-K-T-G-L-G-L-D-Q-V-I-A-F-L-T-V-H-L-A-A"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-T-S-A-T-P-Q-P-G-Q-L-I-V-I-T-G-P-S-G-V-G-K-G-T-L-L-R-Q-L-R-Q-R-H-P-E-L-A-L-S-V-S-A-T-T-R-P-P-R-P-T-E-V-A-G-V-D-Y-Y-F-V-S-V-E-E-F-K-A-M-I-A-A-G-Q-L-L-E-W-A-E-F-A-G-H-Y-Y-G-T-P-R-Q-P-L-V-Q-L-I-A-Q-G-K-T-V-I-L-E-I-E-L-Q-G-A-R-Q-V-R-Q-S-Y-P-Q-A-R-H-I-F-I-L-P-P-S-L-A-E-L-E-H-R-L-R-S-R-G-Q-D-S-E-E-A-I-A-R-R-L-A-Q-A-E-T-E-I-A-A-A-P-E-F-D-V-Q-I-V-N-D-D-L-E-K-S-L-I-A-L-E-T-A-I-F-S-P-A-P"} +{"text": "### FUNCTION Involved in formation and maintenance of cell shape, probably part of the elongasome which synthesizes peripheral peptidogylcan ### SEQUENCE -M-R-Q-L-K-R-V-G-V-F-L-L-L-P-F-F-V-L-I-D-A-H-I-S-Q-L-L-G-S-F-F-P-H-V-H-L-A-S-H-F-L-F-L-F-L-L-F-E-T-I-E-V-S-E-Y-L-Y-L-V-Y-C-F-V-I-G-L-V-Y-D-V-Y-F-F-H-L-I-G-I-T-T-L-L-F-I-L-L-G-A-F-L-H-K-L-N-S-V-I-L-L-N-R-W-T-R-M-L-A-M-I-V-L-T-F-L-F-E-M-G-S-Y-L-L-A-F-M-V-G-L-T-V-D-S-M-S-I-F-I-V-Y-S-L-V-P-T-M-I-L-N-F-L-W-I-T-V-F-Q-F-I-F-E-K-Y-Y-L"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-N-F-R-V-K-R-E-K-D-F-K-A-I-F-K-E-G-T-S-F-A-N-R-K-F-V-V-Y-Q-L-E-N-Q-K-N-H-F-R-V-G-L-S-V-S-K-K-L-G-N-A-V-T-R-N-Q-I-K-R-R-I-R-H-I-I-Q-N-A-K-G-S-L-V-E-D-V-D-F-V-V-I-A-R-K-G-V-E-T-L-G-Y-A-E-M-E-K-N-L-L-H-V-L-K-L-S-K-I-Y-R-E-G-N-G-S-E-K-E-T-K-V-D"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-S-T-L-A-K-I-E-A-L-L-F-V-A-G-E-D-G-I-R-V-R-Q-L-A-E-L-L-S-L-P-P-T-G-I-Q-Q-S-L-G-K-L-A-Q-K-Y-E-K-D-P-D-S-S-L-A-L-I-E-T-S-G-A-Y-R-L-V-T-K-P-Q-F-A-E-I-L-K-E-Y-S-K-A-P-I-N-Q-S-L-S-R-A-A-L-E-T-L-S-I-I-A-Y-K-Q-P-I-T-R-I-E-I-D-A-I-R-G-V-N-S-S-G-A-L-A-K-L-Q-A-F-D-L-I-K-E-D-G-K-K-E-V-L-G-R-P-N-L-Y-V-T-T-D-Y-F-L-D-Y-M-G-I-N-H-L-E-E-L-P-V-I-D-E-L-E-I-Q-A-Q-E-S-Q-L-F-G-E-R-I-E-E-D-E-N-Q"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-L-K-D-R-F-D-R-F-I-D-Y-F-T-E-D-E-D-S-S-L-P-Y-E-K-R-D-E-P-V-F-T-P-V-N-S-S-Q-E-P-A-L-P-M-N-Q-P-S-Q-S-A-G-T-K-E-N-N-I-T-R-L-H-A-R-Q-Q-E-L-A-N-Q-S-Q-R-A-T-D-K-V-I-I-D-V-R-Y-P-R-K-Y-E-D-A-T-E-I-V-D-L-L-A-G-N-E-S-I-L-I-D-F-Q-Y-M-T-E-V-Q-A-R-R-C-L-D-Y-L-D-G-A-C-H-V-L-A-G-N-L-K-K-V-A-S-T-M-Y-L-L-T-P-V-N-V-I-V-N-V-E-D-I-R-L-P-D-E-D-Q-Q-G-E-F-G-F-D-M-K-R-N-R-V-R"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-E-K-T-Y-P-M-T-L-E-E-K-E-K-L-E-K-E-L-E-E-L-K-L-V-R-R-P-E-V-V-E-R-I-K-I-A-R-S-Y-G-D-L-S-E-N-S-E-Y-E-A-A-K-D-E-Q-A-F-V-E-G-Q-I-S-S-L-E-T-K-I-R-Y-A-E-I-V-N-S-D-A-V-A-Q-D-E-V-A-I-G-K-T-V-T-I-Q-E-I-G-E-D-E-E-E-V-Y-I-I-V-G-S-A-G-A-D-A-F-A-G-K-V-S-N-E-S-P-I-G-Q-A-L-I-G-K-K-T-G-D-T-A-T-I-E-T-P-V-G-S-Y-D-V-K-I-L-K-V-E-K-T-A"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-I-T-L-F-L-S-P-S-C-T-S-C-R-K-A-K-A-W-L-E-K-H-K-V-P-F-V-E-H-N-I-M-T-S-P-L-T-R-K-E-L-Q-H-I-L-S-L-T-E-N-G-T-D-D-I-I-S-T-R-S-K-I-F-Q-K-L-N-I-D-V-E-S-I-S-V-S-E-L-L-H-L-I-E-Q-Y-P-S-L-L-R-R-P-I-I-I-D-A-K-R-M-Q-I-G-F-N-E-D-E-I-R-A-F-L-P-R-S-Y-R-K-Q-E-L-K-E-A-R-M-R-A-G-I-S"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-K-K-E-Q-F-Y-P-L-G-I-F-L-A-A-M-L-G-G-L-V-R-Y-L-V-S-T-W-L-P-A-S-P-D-F-P-W-G-T-L-F-V-N-Y-L-G-I-F-C-L-I-F-L-V-K-G-Y-L-V-Y-K-G-T-S-K-G-L-I-L-A-L-G-T-G-F-C-G-G-L-T-T-F-S-S-L-M-L-D-T-V-K-L-L-D-T-G-R-Y-F-S-L-V-L-Y-L-L-L-S-I-G-G-G-L-L-L-A-Y-F-L-G-R-K-K-W"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-V-I-V-Y-L-A-I-A-C-G-F-G-A-L-V-R-Y-F-F-S-R-Y-N-Q-A-S-K-L-P-L-G-T-L-I-A-N-L-L-G-C-F-L-I-G-V-F-Y-N-H-V-E-S-K-E-V-Y-A-I-L-A-T-G-F-C-G-G-L-T-T-F-S-T-L-N-D-E-L-Q-R-L-L-S-D-K-K-V-F-Y-S-Y-L-I-L-T-Y-L-G-G-L-V-A-I-F-L-G-I-L-L"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-G-E-G-K-V-V-A-Q-N-K-K-A-R-H-D-Y-T-I-V-D-T-L-E-A-G-M-V-L-T-G-T-E-I-K-S-V-R-A-A-R-I-N-L-K-D-G-F-A-Q-V-K-N-G-E-V-W-L-S-N-V-H-I-A-P-Y-E-E-G-N-I-W-N-Q-E-P-E-R-R-R-K-L-L-L-H-K-K-Q-I-Q-K-L-E-Q-E-T-K-G-T-G-M-T-L-V-P-L-K-V-Y-I-K-D-G-Y-A-K-L-L-L-G-L-A-K-G-K-H-D-Y-D-K-R-E-S-I-K-R-R-E-Q-N-R-D-I-A-R-V-M-K-A-V-N-Q-R"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-Y-I-E-M-V-D-E-T-G-Q-V-S-K-E-M-L-Q-Q-T-Q-E-I-L-E-F-A-A-Q-K-L-G-K-E-D-K-E-M-A-V-T-F-V-T-N-E-R-S-H-E-L-N-L-E-Y-R-D-T-D-R-P-T-D-V-I-S-L-E-Y-K-P-E-L-E-I-A-F-D-E-E-D-L-L-E-N-P-E-L-A-E-M-M-S-E-F-D-A-Y-I-G-E-L-F-I-S-I-D-K-A-H-E-Q-A-E-E-Y-G-H-S-F-E-R-E-M-G-F-L-A-V-H-G-F-L-H-I-N-G-Y-D-H-Y-T-P-E-E-E-A-E-M-F-G-L-Q-E-E-I-L-T-A-Y-G-L-T-R-Q"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-N-V-I-I-E-K-A-K-E-R-M-T-Q-S-H-Q-S-L-A-R-E-F-G-G-I-R-A-G-R-A-N-A-S-L-L-D-R-V-H-V-E-Y-Y-G-V-E-T-P-L-N-Q-I-A-S-I-T-I-P-E-A-R-V-L-L-V-T-P-F-D-K-S-S-L-K-D-I-D-R-A-L-N-A-S-D-L-G-I-T-P-A-N-D-G-S-V-I-R-L-V-I-P-A-L-T-E-E-T-R-R-D-L-A-K-E-V-K-K-V-G-E-N-A-K-V-A-V-R-N-I-R-R-D-A-M-D-E-A-K-K-Q-E-K-A-K-E-I-T-E-D-E-L-K-T-L-E-K-D-I-Q-K-V-T-D-D-A-V-K-H-I-D-D-M-T-A-N-K-E-K-E-L-L-E-V"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-L-F-D-A-L-D-D-F-S-Q-Q-L-L-V-T-L-A-D-V-E-A-I-K-K-N-L-K-S-L-V-E-E-N-T-A-L-R-L-E-N-S-K-L-R-E-R-L-G-E-V-E-A-D-A-P-V-K-A-K-H-V-R-E-S-V-R-R-I-Y-R-D-G-F-H-V-C-N-D-F-Y-G-Q-R-R-E-Q-D-E-E-C-M-F-C-D-E-L-L-Y-R-E"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-N-Y-F-N-V-G-K-I-V-N-T-Q-G-L-Q-G-E-M-R-V-L-S-V-T-D-F-A-E-E-R-F-K-K-G-A-E-L-A-L-F-D-E-K-D-Q-F-V-Q-T-V-T-I-A-S-H-R-K-Q-K-N-F-D-I-I-K-F-K-D-M-Y-H-I-N-T-I-E-K-Y-K-G-Y-S-L-K-V-A-E-E-D-L-N-D-L-D-D-G-E-F-Y-Y-H-E-I-I-G-L-E-V-Y-E-G-D-S-L-V-G-T-I-K-E-I-L-Q-P-G-A-N-D-V-W-V-V-K-R-K-G-K-R-D-L-L-L-P-Y-I-P-P-V-V-L-N-V-D-I-P-N-K-R-V-D-V-E-I-L-E-G-L-D-D-E-D"} +{"text": "### FUNCTION Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 ### SEQUENCE -M-I-D-V-N-L-I-N-G-I-A-L-A-F-E-G-D-A-V-Y-S-M-Y-I-R-R-H-L-I-L-K-G-M-T-K-P-N-K-L-H-Q-E-A-T-K-Y-V-S-A-K-A-Q-A-R-L-I-A-L-M-L-E-E-Q-V-L-T-E-K-E-E-E-I-Y-K-R-G-R-N-T-N-S-H-T-K-A-K-N-A-D-V-V-T-Y-R-M-S-T-G-F-E-A-V-M-G-Y-L-H-M-T-E-N-L-E-R-L-E-S-L-V-S-W-C-I-Q-K-V-E-G"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-V-N-H-F-R-I-D-R-V-G-M-E-I-K-R-E-V-N-E-I-L-Q-K-K-V-R-D-P-R-V-Q-G-V-T-I-T-D-V-Q-M-L-G-D-L-S-V-A-K-V-Y-Y-T-I-L-S-N-L-A-S-D-N-Q-K-A-Q-I-G-L-E-K-A-T-G-T-I-K-R-E-L-G-R-N-L-K-L-Y-K-I-P-D-L-T-F-V-K-D-E-S-I-E-Y-G-N-K-I-D-E-M-L-R-N-L-D-K-N"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-D-A-I-A-T-I-V-E-L-V-R-E-V-V-E-P-V-I-E-A-P-F-E-L-V-D-I-E-Y-G-K-I-G-S-D-M-I-L-S-I-F-V-D-K-P-E-G-I-T-L-N-D-T-A-D-L-T-E-I-I-S-P-V-L-D-T-I-K-P-D-P-F-P-E-Q-Y-F-L-E-I-T-S-P-G-L-E-R-P-L-K-T-K-D-A-V-A-G-A-V-G-K-Y-I-H-V-G-L-Y-Q-A-I-D-K-Q-K-V-F-E-G-T-L-L-A-F-E-E-D-E-L-T-M-E-Y-M-D-K-T-R-K-K-T-V-R-I-P-Y-S-L-V-S-K-A-R-L-A-V-K-L"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-A-S-I-I-F-S-A-K-D-I-F-E-Q-E-F-G-R-E-V-R-G-Y-N-K-V-E-V-D-E-F-L-D-D-V-I-K-D-Y-E-T-Y-A-A-L-V-K-S-L-R-Q-E-I-A-D-L-K-E-E-L-T-R-K-P-K-P-S-P-V-Q-A-E-P-L-E-A-A-I-T-S-S-M-T-N-F-D-I-L-K-R-L-N-R-L-E-K-E-V-F-G-K-Q-I-L-D-N-S-D-F"} +{"text": "### FUNCTION Essential cell division protein ### SEQUENCE -M-A-E-K-M-E-K-T-G-Q-I-L-Q-M-Q-L-K-R-F-S-R-V-E-K-A-F-Y-F-S-I-A-V-T-T-L-I-V-A-I-S-I-I-F-M-Q-T-K-L-L-Q-V-Q-N-D-L-T-K-I-N-A-Q-I-E-E-K-K-T-E-L-D-D-A-K-Q-E-V-N-E-L-L-R-A-E-R-L-K-E-I-A-N-S-H-D-L-Q-L-N-N-E-N-I-R-I-A-E"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-M-G-L-D-V-G-S-K-T-V-G-V-A-I-S-D-P-L-G-F-T-A-Q-G-L-E-I-I-Q-I-N-E-E-Q-G-Q-F-G-F-D-R-V-K-E-L-V-D-T-Y-K-V-E-R-F-V-V-G-L-P-K-N-M-N-N-T-S-G-P-R-V-E-A-S-Q-A-Y-G-A-K-L-E-E-F-F-G-L-P-V-D-Y-Q-D-E-R-L-T-T-V-A-A-E-R-M-L-I-E-Q-A-D-I-S-R-N-K-R-K-K-V-I-D-K-L-A-A-Q-L-I-L-Q-N-Y-L-D-R-K-F"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-A-Y-L-K-G-I-I-T-K-I-T-A-K-Y-I-V-L-E-T-N-G-I-G-Y-I-L-H-V-A-N-P-Y-A-Y-S-G-Q-V-N-Q-E-A-Q-I-Y-V-H-Q-V-V-R-E-D-A-H-L-L-Y-G-F-R-S-E-D-E-K-K-L-F-L-S-L-I-S-V-S-G-I-G-P-V-S-A-L-A-I-I-A-A-D-D-N-A-G-L-V-Q-A-I-E-T-K-N-I-T-Y-L-T-K-F-P-K-I-G-K-K-T-A-Q-Q-M-V-L-D-L-E-G-K-V-V-V-A-G-D-G-L-P-A-K-V-A-V-Q-A-S-A-E-N-Q-E-L-E-E-A-M-E-A-M-L-A-L-G-Y-K-A-T-E-L-K-K-I-K-K-F-F-E-G-T-T-D-T-A-E-N-Y-I-K-S-A-L-K-M-L-V-K"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-F-Y-Q-E-T-K-E-R-S-P-R-R-E-T-T-R-T-L-Y-L-D-I-D-A-S-S-E-L-E-G-R-I-T-A-R-Q-L-V-E-E-N-R-P-E-Y-N-I-E-Y-I-E-L-L-S-D-K-L-L-D-Y-E-K-E-T-G-A-F-E-I-T-E-F"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-K-L-L-V-G-L-G-N-P-G-D-K-Y-F-E-T-K-H-N-V-G-F-M-L-I-D-Q-L-A-K-K-Q-N-V-T-F-T-H-D-K-I-F-Q-A-D-L-A-S-F-F-L-N-G-E-K-I-Y-L-V-K-P-T-T-F-M-N-E-S-G-K-A-V-H-A-L-L-T-Y-Y-G-L-D-I-D-D-L-L-I-I-Y-D-D-L-D-M-E-V-G-K-I-R-L-R-A-K-G-S-A-G-G-H-N-G-I-K-S-I-I-Q-H-I-G-T-Q-V-F-N-R-V-K-I-G-I-G-R-P-K-N-G-M-S-V-V-H-H-V-L-S-K-F-D-R-D-D-Y-I-G-I-L-Q-S-I-D-K-V-D-D-S-V-N-Y-Y-L-Q-E-K-K-F-E-K-T-M-Q-R-Y-N-G"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-V-K-L-I-T-V-G-K-L-K-E-K-Y-L-K-D-G-I-A-E-Y-C-K-R-L-K-R-F-T-K-F-E-L-E-E-L-P-D-E-K-I-P-N-N-A-S-Q-A-Q-N-T-Y-I-L-E-K-E-G-Q-R-I-L-N-K-I-S-N-R-E-F-V-I-V-L-A-I-E-G-K-Q-F-S-S-E-K-F-S-Q-L-L-S-A-T-M-L-K-G-Y-S-D-L-T-F-V-I-G-G-S-L-G-L-S-Q-E-V-K-K-R-A-S-I-L-M-S-F-G-L-L-T-L-P-H-Q-L-M-R-L-V-F-V-E-Q-I-Y-R-A-F-M-I-Q-E-G-S-P-Y-H-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-A-D-V-K-G-K-G-K-R-G-E-V-K-E-V-S-T-G-Y-A-Q-N-F-L-I-K-K-N-L-A-K-E-A-T-K-Q-A-I-N-E-L-K-G-K-Q-K-S-E-E-K-A-Q-A-E-L-L-A-E-A-K-A-V-K-V-K-L-E-Q-E-S-T-L-V-Q-F-S-E-K-V-G-P-D-G-R-T-F-G-S-I-T-S-K-K-I-S-E-E-L-N-K-Q-F-G-I-K-L-D-K-R-Y-I-K-L-D-H-P-I-R-T-I-G-L-I-E-I-P-V-K-L-H-K-D-I-D-G-I-I-K-L-Q-I-K-E-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-L-S-R-Q-N-K-I-K-Q-I-I-R-S-K-H-I-G-T-Q-E-E-L-K-H-Q-L-E-L-E-K-V-F-V-T-Q-A-T-L-S-R-D-M-R-E-L-G-L-F-K-S-R-D-K-E-G-Y-L-Y-Y-E-I-P-E-N-G-S-T-I-F-T-P-A-A-L-Y-Y-I-K-K-V-F-R-T-D-A-L-L-V-F-H-T-N-L-G-E-A-D-V-L-A-N-L-I-D-S-E-S-H-S-E-I-L-G-T-V-A-G-A-D-T-L-L-V-I-C-K-N-E-E-I-A-S-Q-L-E-S-D-V-L-S-N-L"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-I-G-L-D-V-G-S-K-T-V-G-V-A-V-S-D-P-L-G-F-T-A-Q-G-L-E-I-I-P-I-N-E-A-K-G-E-F-G-F-D-R-L-A-D-L-V-K-D-Y-K-V-E-K-F-V-V-G-L-P-K-N-M-N-N-T-S-G-P-R-V-E-A-S-Q-A-Y-G-K-K-I-K-E-L-F-D-L-P-V-E-Y-Q-D-E-R-L-T-T-V-Q-A-E-R-M-L-V-E-Q-A-D-V-S-R-G-K-R-K-K-V-I-D-K-L-A-A-Q-L-I-L-Q-N-Y-L-D-R-M-F"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-E-I-T-S-A-K-A-M-A-R-T-V-R-V-S-P-R-K-T-R-L-V-L-D-L-I-R-G-K-N-V-A-D-A-I-A-I-L-K-F-T-P-N-K-A-A-R-I-V-E-K-T-L-N-S-A-V-A-N-A-E-N-N-F-G-L-E-K-A-N-L-V-V-S-E-T-F-A-N-E-G-P-T-M-K-R-F-R-P-R-A-K-G-S-A-S-P-I-N-K-R-T-T-H-V-T-V-V-V-E-E-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-H-R-R-E-F-R-G-K-M-R-G-E-A-K-G-G-K-E-V-A-F-G-E-Y-G-L-Q-A-T-T-S-H-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-A-K-A-I-G-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-P-V-K-R-G-K-I-M-F-E-I-A-D-V-P-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-T-K-F-V-K-R-E-A-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-K-Q-R-R-T-L-V-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-K-R-N-H-P-V-Y-G-K-R-I-N-Y-S-K-K-Y-K-A-H-D-E-N-N-I-A-K-A-G-D-I-V-R-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-V-V-E-E-A-V-I-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-S-E-S-R-L-K-V-A-D-N-S-G-A-R-E-I-L-T-I-K-V-L-G-G-S-G-R-K-F-A-N-I-G-D-V-I-V-A-S-V-K-Q-A-T-P-G-G-A-V-K-K-G-D-V-V-K-A-V-I-V-R-T-K-S-G-A-R-R-A-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-R-D-D-K-T-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-F-V-K-K-G-D-K-V-R-V-I-A-G-K-D-K-G-V-E-A-V-V-L-K-A-F-P-K-I-N-K-V-V-V-E-G-V-A-I-V-K-K-H-Q-K-P-N-N-E-N-P-Q-G-A-I-V-E-K-E-A-P-I-H-V-S-N-V-Q-V-L-D-K-N-G-V-A-G-R-V-G-Y-K-V-V-D-G-K-K-V-R-Y-N-K-K-S-G-E-V-L-D"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-N-R-L-K-E-K-Y-L-N-E-V-V-P-A-L-T-E-K-F-N-Y-T-S-V-M-A-V-P-K-V-D-K-I-V-L-N-M-G-V-G-D-A-V-S-N-A-K-N-L-E-K-A-A-A-E-L-A-L-I-S-G-Q-K-P-L-I-T-K-A-K-K-S-I-A-G-F-R-L-R-E-G-V-A-I-G-A-K-V-T-L-R-G-Q-R-M-Y-E-F-L-D-K-L-V-T-V-S-L-P-R-V-R-D-F-H-G-V-P-T-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-N-F-D-N-V-D-K-V-R-G-L-D-I-V-I-V-T-T-A-N-T-D-E-E-S-R-E-L-L-T-G-L-G-M-P-F-A-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-V-A-K-S-K-R-P-A-K-F-S-T-Q-A-Y-T-R-C-E-K-C-G-R-P-H-S-V-Y-R-K-F-K-L-C-R-V-C-F-R-E-L-A-Y-K-G-Q-I-P-G-V-T-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-F-L-T-R-I-R-N-A-N-Q-A-N-H-S-V-V-E-A-P-A-S-N-I-K-R-G-I-A-E-I-L-K-C-E-G-F-V-K-D-V-E-V-I-E-D-D-K-Q-G-I-I-R-I-F-L-K-Y-G-Q-N-G-E-R-V-I-T-G-L-K-R-I-S-K-P-G-L-R-V-Y-T-K-R-E-D-V-P-K-V-L-N-G-L-G-I-A-I-I-S-T-S-E-G-L-L-T-D-R-E-A-R-Q-K-N-I-G-G-E-V-I-T-Y-V-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-V-I-T-L-P-A-G-V-E-V-T-N-K-D-N-V-V-T-V-K-G-P-K-G-E-L-T-R-E-F-P-K-V-I-E-I-K-I-E-G-T-E-V-T-L-H-R-P-N-D-S-K-E-M-K-T-I-H-G-T-A-R-A-N-L-N-N-M-V-I-G-V-S-E-G-F-K-K-E-L-E-M-R-G-V-G-Y-R-A-Q-L-Q-G-K-K-L-V-L-S-V-G-K-S-H-P-D-E-V-E-A-P-E-G-I-T-F-E-V-P-T-A-T-A-I-V-V-N-G-I-N-K-E-V-V-G-Q-T-A-A-Y-I-R-G-L-R-V-P-E-P-Y-K-G-K-G-I-R-Y-A-G-E-Y-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-I-R-Q-K-R-H-R-R-V-R-G-K-L-S-G-T-A-D-R-P-R-L-N-I-F-R-S-N-T-G-I-Y-A-Q-V-I-D-D-V-A-G-V-T-L-A-S-A-S-T-L-D-K-E-V-S-K-G-T-K-T-E-Q-A-V-V-V-G-K-L-V-A-E-R-A-V-A-K-G-I-S-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-N-G-L-K-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-Q-G-S-R-K-T-R-N-R-V-G-R-G-S-S-S-G-N-G-K-T-A-G-R-G-Q-K-G-Q-K-A-R-S-G-G-N-I-R-S-G-F-E-G-G-Q-T-P-L-F-R-R-L-P-K-R-G-F-T-N-I-N-A-K-E-Y-A-L-V-N-L-D-Q-L-N-V-F-E-D-G-A-E-V-T-P-V-V-L-V-E-T-G-I-V-K-A-E-K-S-G-I-K-I-L-G-N-G-E-L-T-K-K-L-T-V-K-A-A-K-F-S-K-S-A-E-A-A-I-I-A-K-G-G-S-I-E-V-I"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-D-V-I-E-I-E-G-K-V-V-E-T-M-P-N-A-M-F-T-V-E-L-E-N-G-H-Q-I-L-A-T-V-S-G-K-I-R-K-N-Y-I-R-I-L-V-G-D-K-V-T-V-E-M-S-P-Y-D-L-T-R-G-R-I-T-Y-R-F-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-I-P-N-D-K-R-V-V-V-S-L-T-Y-V-Y-G-I-G-L-P-T-S-K-K-I-L-A-A-A-G-V-S-E-D-I-R-V-K-D-L-T-S-D-Q-E-D-A-I-R-R-E-V-D-A-I-K-V-E-G-D-L-R-R-E-V-N-L-N-I-K-R-L-M-E-I-G-S-Y-R-G-I-R-H-R-R-G-L-P-V-R-G-Q-N-T-K-N-N-A-R-T-R-K-G-K-A-V-A-I-A-G-K-K-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-K-C-N-Y-L-K-S-S-V-V-D-S-R-Q-A-E-E-G-N-T-I-R-R-R-R-E-C-E-N-C-H-T-R-F-T-T-F-E-R-I-E-E-L-P-L-L-V-V-K-K-D-G-T-R-E-Q-F-S-R-D-K-I-F-N-G-I-I-R-S-A-Q-K-R-P-V-S-S-S-A-I-E-K-V-V-N-D-I-E-Q-K-I-R-S-D-Y-D-S-E-V-S-S-V-V-I-G-N-L-V-M-D-E-L-A-E-L-D-E-I-T-Y-V-R-F-A-S-V-Y-R-S-F-K-D-V-D-E-I-E-A-L-L-Q-Q-I-T-N-R-V-R-S-K-K-K-R-K-A-D-E-T-N"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-K-Y-E-I-L-Y-I-I-R-P-N-I-E-E-E-A-K-N-A-L-V-A-R-F-D-A-V-L-T-D-N-G-A-T-I-V-E-S-K-D-W-E-K-R-R-L-A-Y-E-I-Q-D-F-R-E-G-L-Y-H-V-I-N-V-E-T-E-D-A-H-A-L-N-E-F-D-R-L-S-K-I-N-N-D-I-L-R-H-M-I-V-K-L-D-A"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-N-V-V-L-V-G-R-M-T-R-D-A-E-L-R-Y-T-P-S-N-Q-A-V-A-T-F-T-L-A-V-N-R-N-F-K-N-Q-N-G-E-R-E-A-D-F-I-N-I-V-I-W-R-Q-Q-A-E-N-L-A-N-W-A-K-K-G-T-L-L-G-I-T-G-R-I-Q-T-R-N-Y-E-N-Q-Q-G-Q-R-V-Y-V-T-E-V-V-A-D-N-F-Q-I-L-E-S-R-A-T-R-E-G-Q-S-N-S-Y-N-A-G-G-N-N-N-F-G-G-N-N-F-S-S-Q-G-S-S-Q-S-Q-T-P-N-F-A-R-D-E-S-P-F-G-D-S-N-P-M-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-E-A-S-K-L-K-A-G-M-T-F-E-T-T-D-G-K-L-I-R-V-L-E-A-S-H-H-K-P-G-K-G-N-T-V-M-R-M-K-L-R-D-V-R-T-G-S-T-F-D-T-T-Y-R-P-E-E-K-F-E-Q-A-I-I-E-T-R-P-A-Q-Y-L-Y-Q-M-D-D-T-A-Y-F-M-D-T-E-N-Y-E-Q-Y-E-I-P-I-V-N-I-E-N-E-L-K-F-I-L-E-N-S-E-V-K-I-Q-F-Y-G-S-E-V-I-G-V-T-I-P-T-T-V-E-L-V-V-T-D-T-Q-P-S-I-K-G-A-T-V-T-G-S-G-K-P-A-T-L-E-T-G-L-V-V-N-V-P-D-F-I-E-V-G-Q-K-L-V-I-N-T-A-E-G-T-Y-V-S-R-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-T-N-V-F-V-D-S-R-R-D-L-R-E-R-A-F-Q-A-L-F-S-L-E-F-G-G-D-N-L-T-A-A-R-F-A-Y-T-Y-D-K-N-E-E-E-E-A-E-L-P-L-F-L-L-T-L-I-Q-G-V-S-D-C-R-R-E-I-D-K-N-I-S-I-H-L-K-S-G-W-T-L-S-R-L-T-L-I-D-K-S-L-L-R-L-G-L-Y-E-I-K-Y-H-K-E-T-P-E-R-V-A-L-N-E-I-I-E-I-A-K-K-Y-S-D-E-K-S-S-K-F-I-N-G-V-L-S-Q-F-V-L-E-R-K"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-I-G-H-G-I-D-L-Q-D-I-A-A-V-Q-R-A-H-E-R-S-S-R-F-A-S-K-V-L-T-F-K-E-L-E-I-F-T-S-L-K-G-R-R-Q-V-E-Y-L-A-G-R-W-A-A-K-E-A-F-S-K-A-Y-G-S-G-I-G-S-L-R-F-Q-D-L-E-I-L-A-N-N-K-G-A-P-I-F-T-K-S-P-F-S-G-N-I-F-I-S-I-S-H-S-K-N-Y-V-E-A-S-V-I-L-E-E-N-N-L"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-K-I-S-E-E-E-V-R-H-V-A-N-L-S-K-L-K-F-S-D-D-E-T-T-E-F-A-T-T-L-T-K-I-V-D-M-V-E-L-L-N-E-V-D-T-Q-G-V-P-F-T-S-N-V-A-D-N-I-N-Y-M-R-E-D-V-S-V-A-G-W-D-R-E-Q-L-F-K-N-V-P-E-H-E-D-G-L-I-K-V-P-A-I-I-D-E-G-G-D-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-E-K-T-Y-P-M-T-L-A-E-K-E-Q-L-E-Q-E-L-E-E-L-K-L-V-R-R-P-E-V-I-E-R-I-K-I-A-R-S-Y-G-D-L-S-E-N-S-E-Y-E-A-A-K-D-E-Q-A-F-V-E-G-Q-I-S-S-I-E-T-K-I-R-Y-A-E-I-V-D-S-D-A-V-A-K-N-E-V-A-I-G-K-T-V-I-V-R-E-V-G-T-N-D-E-D-T-Y-S-I-V-G-A-A-G-A-D-V-F-A-G-K-I-S-N-E-S-P-I-A-Q-A-L-I-G-K-K-T-G-D-K-V-M-I-E-S-P-A-G-S-Y-Q-V-E-I-V-K-V-K-K-T-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-N-I-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-I-N-I-M-G-F-T-K-E-F-N-A-R-T-A-D-Q-A-G-M-I-I-P-V-V-I-S-V-Y-E-D-K-S-F-D-F-V-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-D-K-G-S-G-E-P-N-K-T-K-V-A-S-V-T-R-A-Q-V-Q-E-I-A-E-T-K-M-P-D-L-N-A-A-N-L-E-S-A-M-R-M-I-E-G-T-A-R-S-M-G-F-T-V-T-D"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-N-A-I-V-E-K-A-K-E-R-F-E-Q-S-H-Q-S-L-A-R-E-F-G-S-I-R-A-G-R-A-N-A-S-L-L-D-R-I-E-V-E-Y-Y-G-V-P-T-P-L-N-Q-L-A-S-I-T-V-P-E-A-R-V-L-L-V-S-P-F-D-K-S-S-L-K-D-I-E-H-A-I-N-A-S-D-I-G-I-N-P-A-N-D-G-S-V-I-R-L-V-I-P-A-L-T-E-E-T-R-K-E-L-A-K-E-V-K-K-V-G-E-N-A-K-V-A-I-R-N-I-R-R-D-A-M-D-E-A-K-K-Q-E-K-I-K-E-I-T-E-D-E-L-K-S-L-E-K-D-I-Q-K-V-T-D-E-A-V-K-H-I-D-S-M-T-A-N-K-E-K-E-L-L-E-V"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-R-A-I-F-A-G-G-C-F-W-C-M-V-Q-P-F-E-E-Q-D-G-I-L-S-V-R-S-G-Y-T-G-G-H-V-V-N-P-T-Y-E-Q-V-C-S-K-M-T-G-H-T-E-A-V-E-I-I-F-D-E-S-K-I-S-Y-A-D-L-V-E-I-Y-W-R-Q-T-D-P-T-D-S-F-G-Q-F-E-D-R-G-D-N-Y-R-P-V-I-F-Y-F-D-E-Q-Q-R-K-I-A-E-Q-S-K-A-N-L-Q-A-S-G-H-F-N-R-P-I-V-T-T-I-E-A-A-Q-P-F-Y-E-A-E-K-D-H-Q-A-F-Y-R-K-N-P-E-R-Y-A-R-S-S-A-I-R-H-H-F-L-K-E-N-W-S"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-Y-I-E-M-I-D-E-T-N-Q-V-S-E-E-I-K-N-Q-T-L-D-I-L-E-F-A-A-Q-K-T-G-K-E-D-K-E-M-A-V-T-F-V-T-N-E-R-S-H-E-L-N-L-K-Y-R-D-T-N-R-P-T-D-V-I-S-L-E-Y-K-P-E-S-S-L-S-F-D-E-E-D-L-A-D-D-P-D-L-A-E-V-L-T-E-F-D-A-Y-I-G-E-L-F-I-S-V-D-K-A-R-E-Q-A-Q-E-Y-G-H-S-F-E-R-E-M-G-F-L-A-V-H-G-F-L-H-I-N-G-Y-D-H-Y-T-P-Q-E-E-K-E-M-F-S-L-Q-E-E-I-L-D-A-Y-G-L-K-R"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-V-K-A-Q-G-N-V-V-A-Q-N-K-K-A-R-H-D-Y-E-I-L-E-T-Y-E-A-G-I-V-L-T-G-T-E-I-K-S-V-R-A-A-R-I-T-L-K-D-G-F-A-Q-V-K-N-G-E-V-W-L-N-N-V-H-I-T-P-Y-E-Q-G-N-I-W-N-Q-D-P-D-R-T-R-K-L-L-L-K-K-R-E-I-A-K-L-D-N-E-L-K-G-T-G-M-T-L-V-P-L-K-V-Y-L-K-N-G-F-A-K-V-L-I-G-L-A-K-G-K-H-D-Y-D-K-R-E-S-I-K-R-R-E-Q-D-R-D-I-K-R-Q-M-K-Q-F-N-G-R"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-K-N-Y-I-A-T-I-E-D-Y-P-Q-E-G-V-T-F-R-D-I-S-P-L-M-A-N-G-N-A-Y-S-Y-A-I-R-E-I-V-Q-Y-A-T-D-K-K-I-D-M-I-V-G-P-E-A-R-G-F-I-V-G-C-P-V-A-Y-E-L-G-V-G-F-A-P-V-R-K-P-G-K-L-P-R-E-V-I-E-A-H-Y-E-K-E-Y-G-I-D-T-L-T-M-H-A-D-A-I-K-P-G-Q-R-V-L-I-V-D-D-L-L-A-T-G-G-T-V-K-A-T-I-E-M-I-E-R-L-G-G-I-V-A-G-C-A-F-L-I-E-L-D-G-L-D-G-R-Q-A-I-E-G-Y-D-T-K-V-L-M-N-F-P-G"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-R-M-I-L-M-F-D-M-P-T-D-T-A-E-E-R-K-A-Y-R-K-F-R-K-F-L-L-S-E-G-F-I-M-H-Q-F-S-V-Y-S-K-L-L-L-N-N-S-A-N-T-A-M-I-A-R-L-K-E-N-N-P-K-K-G-N-I-T-L-L-T-V-T-E-K-Q-F-A-R-M-I-Y-L-N-G-E-R-D-T-S-I-A-N-S-D-S-R-L-V-F-L-G-E-A-F-P-D-E-T"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-E-F-T-I-Y-T-G-T-T-V-P-L-M-N-D-N-I-D-T-D-Q-I-L-P-K-Q-F-L-K-L-I-D-K-K-G-F-G-K-Y-L-M-Y-E-W-R-Y-L-D-N-N-Y-T-E-N-P-D-F-I-F-N-Q-P-E-Y-R-E-A-S-I-L-I-T-G-D-N-F-G-A-G-S-S-R-E-H-A-A-W-A-L-A-D-Y-G-F-K-V-I-V-A-G-S-F-G-D-I-H-Y-N-N-D-L-N-N-G-I-L-P-I-I-Q-P-K-E-V-R-D-K-L-A-K-L-K-P-T-D-E-V-T-V-N-L-F-E-Q-K-I-Y-S-P-V-G-D-F-S-F-D-I-D-G-E-W-K-H-K-L-L-N-G-L-D-D-I-G-I-T-L-Q-Y-E-D-L-I-A-Q-Y-E-Q-N-R-P-S-Y-W-H"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-P-L-I-Q-S-L-T-E-S-Q-L-R-T-D-I-P-N-F-R-P-G-D-T-V-R-V-H-A-K-V-V-E-G-N-R-E-R-V-Q-I-F-E-G-V-V-I-S-R-K-G-Q-G-I-S-E-M-Y-T-V-R-K-I-S-S-G-V-G-V-E-R-T-F-P-T-H-T-P-R-V-E-K-I-E-V-T-R-H-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-Q-G-K-A-A-R-I-K-E-V-R-Q"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-T-L-F-L-S-P-S-C-T-S-C-R-K-A-R-A-W-L-N-R-H-D-V-V-F-Q-E-H-N-I-M-T-S-P-L-S-R-D-E-L-L-K-I-L-S-Y-T-E-N-G-T-E-D-I-I-S-T-R-S-K-V-F-Q-K-L-D-I-D-V-D-E-L-S-V-S-E-L-I-N-L-I-S-K-N-P-S-L-L-R-R-P-I-I-M-D-N-K-R-M-Q-I-G-F-N-E-D-E-I-R-A-F-L-P-R-D-Y-R-K-Q-E-L-R-Q-A-T-I-R-A-E-V-E-G-E-D-D"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-A-E-L-N-V-K-Q-N-N-R-N-S-A-Q-K-S-A-M-R-S-A-I-K-A-F-E-A-N-P-N-E-E-L-F-R-A-A-S-S-S-I-D-K-A-K-S-K-G-L-I-H-K-N-K-A-S-R-D-K-A-R-L-A-S-K-L-A-K"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-D-I-K-Q-T-A-V-A-G-S-L-E-S-S-D-I-M-V-T-V-N-P-S-D-V-Q-G-I-T-V-Q-L-E-S-S-V-E-K-Q-F-G-Q-Q-I-R-K-V-I-E-E-T-L-K-H-L-G-V-K-A-A-S-V-E-A-V-D-K-G-A-L-D-C-T-I-K-A-R-T-I-T-A-V-H-R-A-A-Q-V-E-V-Y-D-W-K-E-I-D-S-W-N-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-N-I-E-N-I-I-A-E-I-K-E-A-S-I-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-A-A-G-A-A-G-G-E-E-A-A-A-K-D-S-F-D-I-E-L-T-A-G-G-D-K-K-V-A-V-I-K-V-V-R-E-I-T-G-E-G-L-K-E-A-K-G-L-V-D-N-A-P-S-V-L-K-E-G-V-A-A-A-E-A-E-E-L-K-A-K-L-E-E-A-G-A-T-V-T-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-E-A-S-I-A-K-K-A-E-L-V-D-A-V-A-E-K-M-K-A-A-V-S-I-V-V-V-D-S-R-G-L-T-V-E-Q-D-T-V-L-R-R-N-L-R-E-S-A-V-E-F-K-V-I-K-N-S-I-L-R-R-A-A-E-K-A-G-L-E-G-F-D-D-I-F-T-G-P-S-A-V-A-F-S-N-E-D-V-V-A-P-A-K-I-I-N-D-F-A-K-D-A-E-A-L-E-I-K-G-G-A-I-E-G-A-V-S-T-K-E-E-I-Q-A-L-A-A-L-P-N-R-E-G-L-L-S-M-L-L-S-V-L-Q-A-P-V-R-N-V-A-Y-A-V-K-A-V-A-E-S-K-D-E-D-A-A"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-S-E-F-L-N-T-H-N-A-S-I-L-L-S-A-V-N-K-S-H-Y-P-Q-D-D-L-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-L-L-G-R-K-N-L-A-R-T-S-S-K-P-G-K-T-Q-S-L-N-F-Y-N-I-D-D-K-L-R-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-K-E-R-A-K-W-G-K-M-I-E-E-Y-L-T-S-R-E-N-L-R-A-V-V-S-L-V-D-F-R-H-D-P-S-S-D-D-V-Q-M-Y-D-F-L-K-Y-Y-E-I-P-V-I-L-V-A-T-K-A-D-K-V-P-R-G-K-W-N-K-Q-E-S-A-I-K-K-K-L-D-F-D-S-N-D-A-F-I-I-F-S-S-V-D-R-T-G-L-D-T-S-W-D-A-I-L-E-S-L"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-Y-F-N-V-G-K-I-V-N-T-Q-G-L-R-G-E-V-R-V-L-S-V-T-D-F-A-D-E-R-F-K-K-G-S-Q-L-A-L-F-D-K-K-D-H-F-A-M-T-V-E-I-A-S-H-R-K-H-K-N-F-D-I-V-K-F-K-G-L-Y-H-I-N-D-V-E-K-Y-R-D-F-T-L-K-V-T-E-D-H-L-A-D-L-E-D-G-E-F-Y-Y-H-E-I-I-G-L-D-V-Y-E-N-D-I-L-I-G-Q-V-K-E-I-L-Q-P-G-A-N-D-V-W-V-V-K-R-K-G-K-K-D-L-L-L-P-Y-I-P-S-V-I-L-K-V-D-V-P-N-G-R-I-D-V-T-V-L-E-G-L-D-D-E-N"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-K-T-K-E-I-V-D-G-V-T-M-K-R-A-I-T-R-M-T-Y-E-I-I-E-R-N-K-N-L-D-N-I-V-L-A-G-I-K-T-R-G-V-F-I-A-R-R-I-Q-E-R-L-K-Q-I-E-G-L-D-V-P-L-G-E-L-D-T-K-S-F-R-D-D-V-K-V-E-E-N-T-T-E-M-P-V-D-I-T-N-R-D-V-I-L-V-D-D-V-L-Y-T-G-R-T-I-R-A-A-I-D-N-I-V-N-L-G-R-P-A-R-V-S-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-S-S-E-E-I-V-V-N-M-V-E-I-D-D-K-D-N-V-L-L-L-A-K-E-D-S-L"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-T-Y-A-I-I-K-T-G-G-K-Q-V-K-V-E-V-D-Q-A-I-Y-V-E-K-L-D-V-E-A-G-A-E-V-T-F-D-Q-V-V-L-V-G-G-D-K-T-V-V-G-T-P-I-V-Q-G-A-T-V-V-G-T-V-E-K-Q-G-K-Q-K-K-V-V-T-Y-K-Y-K-P-K-K-G-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-K-A-I-N-A"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-G-G-V-V-S-R-K-R-R-K-R-V-L-K-L-A-K-G-Y-Y-G-A-K-H-I-L-F-R-T-A-K-E-Q-V-M-N-S-Y-Y-Y-A-Y-R-D-R-R-Q-R-K-R-D-F-R-K-L-W-I-T-R-I-N-A-A-A-R-M-N-G-L-S-Y-S-Q-L-M-H-G-L-K-L-A-E-V-E-V-N-R-K-M-L-A-D-L-A-V-N-D-A-A-A-F-T-V-L-A-D-A-A-K-E-K-L-G-K"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-N-I-A-K-K-D-L-F-I-N-N-E-I-R-V-R-E-V-R-L-I-G-L-D-G-E-Q-L-G-I-K-P-L-A-Q-A-Q-A-I-A-D-D-A-N-V-D-L-V-L-I-Q-P-Q-A-T-P-P-V-A-R-I-M-D-Y-G-K-F-K-F-E-Y-Q-K-K-Q-K-E-Q-R-K-K-Q-S-V-V-T-I-K-E-V-R-L-S-P-V-I-D-K-G-D-F-E-T-K-L-R-N-G-R-K-F-L-E-K-G-N-K-V-K-V-S-I-R-F-K-G-R-M-I-T-H-K-E-I-G-A-K-V-L-A-D-F-A-E-A-T-Q-D-I-A-I-I-E-Q-R-A-K-M-D-G-R-Q-M-F-M-Q-L-A-P-I-P-D-K-K"} +{"text": "### FUNCTION Folate-binding protein that interacts with the energy-coupling factor ### SEQUENCE -M-N-T-M-F-K-S-P-K-L-S-P-Q-R-L-V-T-L-A-M-L-I-A-L-A-F-A-I-G-K-L-S-I-P-I-I-P-Q-Q-L-I-I-S-P-T-F-I-V-N-V-M-I-G-M-I-G-G-P-I-W-A-F-I-S-L-A-I-L-D-I-V-D-N-L-S-S-G-A-G-N-F-I-I-W-W-T-L-L-E-A-V-Q-G-L-F-Y-G-L-F-F-Y-Q-K-S-L-S-W-T-N-K-K-D-W-L-H-V-T-I-A-T-A-I-I-M-L-I-G-S-F-I-F-T-P-L-L-V-Q-I-Y-Y-G-V-P-F-W-A-Q-F-A-A-G-R-W-L-K-I-F-E-I-P-I-R-I-L-V-T-M-A-I-M-P-Q-L-Q-R-I-P-E-L-R-K-L-A-N-F-K"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-L-Y-P-T-P-I-A-K-L-I-E-S-F-T-K-L-P-G-I-G-I-K-T-A-T-R-L-A-F-Y-T-I-G-M-S-D-E-D-V-N-N-F-A-K-N-L-L-A-A-K-R-E-L-T-Y-C-S-V-C-G-N-L-T-D-D-D-P-C-N-I-C-T-D-E-S-R-D-R-S-T-V-L-V-V-E-D-S-K-D-V-S-A-M-E-K-I-Q-E-Y-H-G-L-Y-H-V-L-H-G-L-I-S-P-M-N-G-I-G-P-D-D-I-N-L-K-S-L-L-T-R-L-R-D-N-S-D-I-H-E-V-I-I-A-T-N-A-T-A-D-G-E-A-T-A-M-Y-I-S-R-V-L-K-P-A-G-I-T-V-T-R-L-A-R-G-L-A-V-G-S-D-I-E-Y-A-D-E-V-T-L-L-R-A-I-E-N-R-T-E-L"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-S-N-K-K-K-T-F-E-E-N-L-Q-D-L-E-E-I-V-N-Q-L-E-T-G-E-I-P-L-E-E-A-I-T-Q-F-Q-K-G-M-A-L-S-K-D-L-Q-K-T-L-E-S-A-E-K-T-L-V-K-V-M-Q-A-D-G-S-E-A-E-M-D-E-L"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-L-R-D-S-F-N-K-I-I-S-Y-F-D-T-D-E-V-S-E-V-E-E-P-A-V-A-S-V-K-R-Q-Q-D-A-A-Q-P-A-S-Q-Q-Q-K-A-Q-S-H-Q-Y-H-Q-S-A-S-R-P-S-Q-Q-Q-V-Q-S-G-Q-N-R-R-S-G-E-E-N-I-H-S-L-P-T-R-R-Q-S-H-N-Q-Q-P-A-Q-E-K-T-T-I-A-L-K-L-P-R-K-Y-E-D-A-E-E-I-V-D-L-L-I-R-N-E-C-V-L-I-D-F-Q-Y-M-L-E-A-Q-A-R-R-C-L-D-F-I-D-G-A-S-K-V-L-A-G-N-L-Q-K-V-G-A-S-M-Y-L-L-T-P-I-N-V-I-V-D-A-E-E-M-T-L-A-A-N-G-Q-D-V-S-F-N-Y-D-M-K-R-R"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-M-L-K-P-S-I-D-T-L-L-D-K-V-P-S-K-Y-S-L-V-I-L-Q-A-K-R-A-H-E-L-E-S-G-A-T-P-T-Q-A-F-T-S-V-K-P-T-L-Q-A-L-E-E-I-E-A-G-N-V-V-I-H-P-D-P-E-A-K-R-A-A-V-R-A-R-A-E-A-E-R-I-A-K-E-E-E-E-R-K-I-K-E-Q-I-A-K-E-K-E-E-E-G-E-K-I"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-T-K-E-V-T-V-E-S-F-E-L-D-H-I-A-V-K-A-P-Y-V-R-L-I-S-E-E-F-G-P-K-G-D-L-I-T-N-F-D-I-R-L-V-Q-P-N-E-D-S-I-P-T-A-G-L-H-T-I-E-H-L-L-A-K-L-I-R-Q-R-I-D-G-M-I-D-C-S-P-F-G-C-R-T-G-F-H-L-I-M-W-G-K-H-T-T-T-Q-I-A-T-V-I-K-A-S-L-E-E-I-A-N-T-I-S-W-K-D-V-P-G-T-T-I-E-S-C-G-N-Y-K-D-H-S-L-F-S-A-K-E-W-A-K-L-I-L-K-Q-G-I-S-D-D-P-F-E-R-H-L-V"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-A-S-I-M-Y-T-P-K-D-I-F-E-Q-E-F-K-S-S-M-R-G-Y-D-K-K-E-V-D-E-F-L-D-D-I-I-K-D-Y-E-T-Y-I-S-T-I-E-E-L-R-Q-E-N-T-R-L-K-E-E-V-K-Q-A-K-K-R-Q-E-A-A-Q-T-T-V-S-P-A-A-S-V-S-S-S-R-V-A-T-T-A-T-N-F-D-I-L-K-R-I-S-R-L-E-K-E-V-F-G-K-Q-I-T-E"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-N-H-R-I-E-R-V-G-M-E-I-K-R-E-V-N-E-I-L-Q-K-K-V-R-D-P-R-V-Q-G-V-T-I-T-D-V-Q-M-S-G-D-L-S-L-A-K-V-Y-Y-T-I-M-S-D-L-A-S-D-N-Q-K-V-Q-I-G-L-E-K-A-K-G-T-I-K-R-E-L-G-K-N-L-T-M-Y-K-I-P-D-L-T-F-I-K-D-E-S-I-E-Y-G-N-K-I-D-Q-M-L-R-D-L-E-K-R-N"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-C-K-E-G-N-T-I-A-T-L-V-D-I-V-R-P-V-V-A-P-V-I-P-K-P-F-E-L-V-D-I-E-Y-E-K-L-G-G-N-Y-V-L-S-I-L-V-D-K-P-E-G-I-T-V-E-D-T-A-D-L-T-D-I-I-S-P-L-L-D-T-I-K-P-D-P-F-P-E-Q-Y-M-L-E-I-S-S-P-G-L-E-R-P-L-K-T-A-Q-S-L-M-N-A-V-G-H-Y-I-N-V-S-L-Y-Q-A-I-D-K-V-K-V-F-E-G-D-L-T-A-F-D-G-E-T-L-K-M-T-Y-L-D-K-T-Q-Q-K-T-V-T-I-P-Y-K-M-V-A-K-A-R-L-A-V-K-L"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-N-M-Q-N-M-M-K-Q-A-Q-K-L-Q-K-Q-M-E-K-K-Q-S-E-L-A-S-M-T-F-V-G-K-S-A-Q-D-L-V-V-A-T-F-T-G-N-K-K-L-V-S-I-D-F-K-E-A-V-V-D-P-D-D-R-E-T-L-Q-D-M-T-V-Q-A-I-N-D-A-L-G-Q-I-E-D-A-T-Q-K-T-M-G-A-F-A-G-K-L-P-F"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-F-Y-Q-E-T-K-D-S-S-P-R-R-E-Q-T-K-T-L-Y-L-D-I-D-A-Q-T-E-L-D-G-R-I-Q-A-R-Q-L-V-E-E-K-I-A-Y-N-I-E-L-I-E-L-L-S-D-K-H-L-E-Y-E-K-E-T-G-A-F-Q-L-T-E-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-N-R-A-P-K-R-E-V-L-P-D-P-L-Y-N-S-K-L-V-T-R-L-I-N-R-I-M-L-D-G-K-R-G-T-A-A-S-I-V-Y-G-A-F-E-Q-I-K-E-A-T-G-N-D-A-L-E-V-F-E-Q-A-M-E-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-S-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-T-A-S-R-T-R-G-E-H-T-M-K-D-R-L-A-K-E-I-L-D-A-S-N-N-T-G-A-S-V-K-K-R-E-D-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R-W"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-A-Y-R-V-K-S-D-K-D-F-Q-A-I-F-T-E-G-R-S-V-A-N-R-K-F-V-V-Y-S-L-E-K-D-Q-S-H-Y-R-V-G-L-S-V-G-K-R-L-G-N-A-V-V-R-N-A-I-K-R-K-L-R-H-V-L-M-E-L-G-P-Y-L-G-T-Q-D-F-V-V-I-A-R-K-G-V-E-E-L-D-Y-S-T-M-K-K-N-L-V-H-V-L-K-L-A-K-L-Y-Q-E-G-S-I-R-E-K-E-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-N-E-I-I-K-Q-Y-A-R-H-D-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-W-E-I-N-H-L-N-E-H-I-K-Q-H-K-K-D-H-A-T-Y-R-G-L-M-K-K-I-G-H-R-R-N-L-L-A-Y-L-R-R-T-D-V-N-R-Y-R-D-L-I-S-S-L-G-L-R-R"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-E-L-E-V-F-A-G-Q-E-K-S-E-L-S-M-I-E-V-A-R-A-I-L-E-E-R-G-R-D-K-E-M-Y-F-S-D-L-V-N-A-I-Q-V-Y-L-E-K-S-D-A-D-I-R-E-A-L-P-F-F-Y-S-D-L-N-T-D-G-S-F-I-P-L-G-E-N-K-W-G-L-R-S-W-Y-G-I-D-E-I-D-E-E-I-V-T-L-E-E-D-E-D-G-A-P-K-H-K-R-K-R-V-N-A-F-M-D-G-D-E-D-A-I-D-Y-S-D-D-D-P-E-D-E-S-F-N-T-A-E-E-D-T-E-Y-D-E-E-D-P-D-D-E-K-S-E-V-E-S-Y-D-S-E-I-N-E-I-I-P-D-E-D-L-D-E-N-V-D-L-D-E-E-D-D-D-Y-S-D-D-E-E-D-E-E-G-E"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-K-L-I-V-G-L-G-N-P-G-S-K-Y-H-E-T-K-H-N-V-G-F-M-A-L-D-R-I-V-K-P-L-N-V-Q-F-T-E-N-K-T-F-K-A-E-T-V-A-T-F-I-N-G-E-K-I-Y-F-I-K-P-T-T-F-M-N-A-S-G-L-A-V-R-A-F-L-A-Y-Y-N-L-T-V-E-D-L-I-V-I-Y-D-D-L-D-M-E-V-G-K-I-R-F-R-Q-K-G-S-A-G-G-H-N-G-I-K-S-I-I-K-E-I-G-T-Q-E-F-D-R-I-K-I-G-I-G-R-P-K-D-K-M-T-V-V-N-Y-V-L-G-K-F-D-K-K-D-E-I-T-I-F-N-T-L-D-K-V-D-K-A-V-N-Y-Y-L-Q-T-K-N-F-E-Q-T-M-Q-K-F-N-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-Q-D-V-K-G-K-G-K-K-G-E-V-K-E-V-P-T-G-Y-A-Q-N-F-L-L-K-K-N-L-A-K-E-A-T-T-Q-A-I-G-E-L-K-G-K-Q-K-S-E-E-K-A-Q-A-E-I-L-A-Q-A-K-E-L-K-T-Q-L-E-S-E-T-T-R-V-Q-F-I-E-K-V-G-P-D-G-R-T-F-G-S-I-T-A-K-K-I-A-E-E-L-Q-K-Q-Y-G-I-K-I-D-K-R-H-I-D-L-D-H-T-I-R-A-I-G-K-V-E-V-P-V-K-L-H-K-Q-V-S-S-Q-I-K-L-D-I-K-E-A"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-D-Y-I-K-G-K-L-S-K-I-T-A-K-F-I-V-V-E-T-A-G-L-G-Y-M-I-Y-V-A-N-P-Y-S-F-S-G-Y-V-N-Q-E-V-T-I-Y-L-H-Q-V-I-R-D-D-A-H-L-L-F-G-F-H-T-E-N-E-K-E-I-F-L-N-L-I-S-V-S-G-I-G-P-T-T-A-L-A-I-I-A-V-D-D-N-E-G-L-V-S-A-I-D-N-S-D-I-K-Y-L-T-K-F-P-K-I-G-K-K-T-A-Q-Q-M-I-L-D-L-S-G-K-F-V-E-A-S-G-E-S-A-T-S-R-K-V-S-S-E-Q-N-S-N-L-E-E-A-M-E-A-L-L-A-L-G-Y-K-A-T-E-L-K-K-V-K-A-F-F-E-G-T-N-E-T-V-E-Q-Y-I-K-S-S-L-K-M-L-M-K"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-N-V-V-L-I-G-R-L-T-R-D-V-E-L-R-Y-T-P-S-N-I-A-N-A-T-F-N-L-A-V-N-R-N-F-K-N-A-A-G-D-R-E-A-D-F-I-N-C-V-M-W-R-Q-Q-A-E-N-L-A-N-W-T-K-K-G-M-L-I-G-I-T-G-R-I-Q-T-R-S-Y-E-N-Q-Q-G-Q-R-I-Y-V-T-E-V-V-A-D-S-F-Q-I-L-E-K-R-D-N-S-T-N-Q-A-S-M-D-D-Q-L-P-P-S-F-G-N-S-Q-P-M-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-K-P-R-K-S-K-V-E-K-S-D-S-P-A-L-N-I-G-Y-N-S-H-R-K-V-H-T-K-L-S-A-P-Q-K-R-G-V-A-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-F-A-R-V-R-L-S-N-L-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-T-A-G-V-A-D-R-K-Q-G-R-S-K-Y-G-A-K-R-P-K-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-N-Q-A-P-K-R-E-V-L-P-D-P-L-Y-N-S-K-I-V-T-R-L-I-N-R-V-M-L-D-G-K-R-G-T-A-A-T-I-V-Y-D-A-F-E-A-I-K-E-A-T-G-T-D-A-L-E-V-F-E-T-A-M-E-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-S-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-N-A-S-R-A-R-G-E-H-T-M-K-D-R-L-A-K-E-I-M-D-A-A-N-N-T-G-A-S-V-K-K-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-F-R-W"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-F-Y-Q-E-T-K-E-R-N-P-R-R-E-Q-T-K-T-L-Y-V-T-I-D-A-A-N-E-L-E-G-R-I-A-A-R-K-L-V-E-E-N-T-A-Y-N-I-E-F-I-E-L-L-S-D-K-H-L-E-Y-E-K-E-T-G-V-F-E-L-T-E-F"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-F-Q-K-Q-Q-K-L-V-E-Q-Y-A-E-L-R-R-E-L-K-E-K-G-D-Y-E-A-L-R-K-L-P-K-D-S-N-P-N-R-L-K-N-R-D-L-I-D-G-R-P-H-A-Y-M-R-K-F-G-M-S-R-I-N-F-R-N-L-A-Y-K-G-Q-I-P-G-I-K-K-A-S-W"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Q-Q-R-R-G-G-F-K-R-R-K-K-V-D-Y-I-A-A-N-K-I-E-Y-V-D-Y-K-D-T-E-L-L-S-R-F-V-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-N-Q-R-K-V-T-T-A-I-K-R-A-R-V-M-A-L-M-P-Y-V-N-E-D"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-K-I-S-E-E-E-V-R-H-V-A-N-L-S-K-L-R-F-S-D-Q-E-T-K-E-F-A-S-S-L-S-K-I-V-D-M-I-E-L-L-N-E-V-D-T-E-G-V-P-V-T-T-T-M-A-D-R-K-T-V-M-R-E-D-I-A-Q-P-G-H-N-R-D-D-L-F-K-N-V-P-Q-H-Q-D-Y-Y-I-K-V-P-A-I-L-E-D-G-G-D-A"} +{"text": "### FUNCTION Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP ### SEQUENCE -M-T-Y-K-D-Y-T-G-L-D-R-T-E-L-L-S-K-V-R-H-M-M-S-D-K-R-F-N-H-V-L-G-V-E-R-A-A-I-E-L-A-E-R-Y-G-Y-D-K-E-K-A-G-L-A-A-L-L-H-D-Y-A-K-E-L-S-D-D-E-F-L-R-L-I-D-K-Y-Q-P-D-P-D-L-K-K-W-G-N-N-I-W-H-G-L-V-G-I-Y-K-I-Q-E-D-L-A-I-K-D-Q-D-I-L-A-A-I-A-K-H-T-V-G-S-A-Q-M-S-T-L-D-K-I-V-Y-V-A-D-Y-I-E-H-N-R-D-F-P-G-V-E-E-A-R-E-L-A-K-V-D-L-N-K-A-V-A-Y-E-T-A-R-T-V-A-F-L-A-S-K-A-Q-P-I-Y-P-K-T-I-E-T-Y-N-A-Y-I-P-Y-L-D"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-K-C-G-Y-N-K-S-S-V-V-D-S-R-Q-A-E-E-G-T-T-I-R-R-R-R-E-C-E-K-C-G-N-R-F-T-T-F-E-R-L-E-E-L-P-L-L-V-I-K-K-D-G-T-R-E-Q-F-S-R-D-K-I-L-N-G-I-I-Q-S-A-Q-K-R-P-V-S-S-E-D-I-E-N-C-I-L-R-I-E-R-K-I-R-S-E-Y-E-D-E-V-S-S-I-T-I-G-N-L-V-M-D-E-L-A-E-L-D-E-I-T-Y-V-R-F-A-S-V-Y-K-S-F-K-D-V-D-E-I-E-E-L-L-Q-Q-I-T-K-R-V-R-S-K-K-S-G-S-V"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-E-K-T-Y-P-M-T-Q-V-E-K-D-Q-L-E-K-E-L-E-E-L-K-L-V-R-R-P-E-V-V-E-R-I-K-I-A-R-S-Y-G-D-L-S-E-N-S-E-Y-D-A-A-K-D-E-Q-A-F-V-E-G-Q-I-Q-I-L-E-T-K-I-R-Y-A-E-I-I-D-S-D-A-V-A-K-D-E-V-A-I-G-K-T-V-L-V-Q-E-V-G-T-N-D-K-D-T-Y-H-I-V-G-A-A-G-A-D-I-F-S-G-K-I-S-N-E-S-P-I-A-H-A-L-I-G-K-K-T-G-D-L-A-T-I-E-S-P-A-G-S-Y-Q-V-E-I-I-S-V-E-K-T-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-S-F-L-I-F-L-V-R-F-Y-Q-K-N-I-S-P-A-F-P-A-S-C-R-Y-R-P-T-C-S-T-Y-M-I-E-A-I-Q-K-H-G-L-K-G-V-L-M-G-I-A-R-I-L-R-C-H-P-L-A-H-G-G-N-D-P-V-P-D-H-F-S-L-R-R-N-K-T-D-I-S-D"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-I-P-V-V-I-E-Q-T-S-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-T-G-Q-V-E-D-N-M-A-N-S-I-I-A-Q-L-L-F-L-D-A-Q-D-N-T-K-D-I-Y-L-Y-V-N-T-P-G-G-S-V-S-A-G-L-A-I-V-D-T-M-N-F-I-K-S-D-V-Q-T-I-V-M-G-M-A-A-S-M-G-T-I-I-A-S-S-G-A-K-G-K-R-F-M-L-P-N-A-E-Y-M-I-H-Q-P-M-G-G-T-G-G-G-T-Q-Q-S-D-M-A-I-A-A-E-H-L-L-K-T-R-H-T-L-E-K-I-L-A-D-N-S-G-Q-S-I-E-K-V-H-D-D-A-E-R-D-R-W-M-S-A-Q-E-T-L-D-Y-G-F-I-D-A-I-M-E-N-N-N-L-Q"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-K-L-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-I-N-I-M-G-F-T-K-E-F-N-A-R-T-A-D-Q-A-G-M-I-I-P-V-V-I-S-V-Y-E-D-K-S-F-D-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-E-K-G-S-G-E-P-N-K-T-K-V-A-T-I-T-R-A-Q-V-Q-E-I-A-E-T-K-M-P-D-L-N-A-A-N-L-E-S-A-M-R-M-I-E-G-T-A-R-S-M-G-F-T-V-T-D"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-R-A-I-F-A-G-G-C-F-W-C-M-V-Q-P-F-E-E-L-D-G-I-E-S-V-L-S-G-Y-T-G-G-H-V-E-N-P-T-Y-K-E-V-C-S-K-T-T-G-H-T-E-A-V-E-I-I-F-N-P-E-K-I-S-Y-A-D-L-V-E-L-Y-W-A-Q-T-D-P-T-D-A-F-G-Q-F-E-D-R-G-D-N-Y-R-P-V-I-F-Y-E-N-E-E-Q-R-Q-I-A-Q-K-S-K-D-K-L-Q-A-S-G-R-F-D-R-P-I-V-T-S-I-E-P-A-D-T-F-Y-P-A-E-D-Y-H-Q-A-F-Y-R-T-N-P-A-R-Y-A-L-S-S-A-R-R-H-A-F-L-E-E-N-W-H"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-T-Y-A-I-I-K-T-G-G-K-Q-V-K-V-E-V-G-Q-A-I-Y-V-E-K-L-D-V-E-A-G-A-E-V-T-F-N-E-V-V-L-V-G-G-E-T-T-K-V-G-T-P-V-V-E-G-A-T-V-V-G-T-V-E-K-Q-G-K-Q-K-K-V-V-S-Y-K-Y-K-P-K-K-G-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-N-A-I-N-A"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-K-R-K-E-I-I-D-D-V-T-M-K-R-A-I-T-R-I-T-Y-E-I-I-E-R-N-K-N-L-D-N-I-V-L-A-G-I-K-T-R-G-V-F-L-A-K-R-I-Q-E-R-L-K-Q-L-E-N-L-D-I-P-V-G-E-L-D-T-K-P-F-R-D-D-M-K-V-E-V-D-T-T-T-M-P-V-D-I-T-D-K-D-I-I-L-I-D-D-V-L-Y-T-G-R-T-I-R-A-A-I-D-N-L-V-S-L-G-R-P-S-R-V-S-L-A-V-L-I-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-Q-F-E-E-I-L-V-E-V-M-E-H-D-G-Y-D-R-V-S-I-I-D-P-S"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-Y-F-N-V-G-K-I-V-N-T-Q-G-L-Q-G-E-M-R-V-L-S-V-T-D-F-V-E-E-R-F-K-K-G-Q-V-L-A-L-F-D-E-K-N-Q-F-V-M-D-I-E-I-A-S-H-R-K-Q-K-N-F-D-I-I-K-F-K-G-M-Y-H-I-N-D-I-E-K-Y-K-G-F-T-L-K-V-A-E-D-Q-L-S-D-L-K-D-G-E-F-Y-Y-H-E-I-I-G-L-D-V-Y-E-G-E-E-L-I-G-K-I-K-E-I-L-Q-P-G-A-N-D-V-W-V-V-E-R-H-G-K-R-D-L-L-L-P-Y-I-P-P-V-V-L-E-V-D-L-S-N-Q-R-V-Q-V-E-L-M-E-G-L-D-D-E-D"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-A-E-E-F-L-N-T-H-N-A-S-I-L-L-S-A-A-N-K-S-H-Y-P-Q-D-D-L-P-E-V-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-L-L-G-R-K-N-L-A-R-T-S-S-K-P-G-K-T-Q-L-L-N-F-Y-N-I-D-D-K-L-R-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-T-E-R-A-K-W-G-K-M-I-E-E-Y-L-V-T-R-D-N-L-R-V-V-V-S-L-V-D-F-R-H-D-P-S-A-D-D-I-Q-M-Y-E-F-L-K-Y-Y-E-I-P-V-I-I-V-A-T-K-A-D-K-I-P-R-G-K-W-N-K-H-E-S-S-I-K-K-K-L-N-F-D-K-K-D-H-F-I-V-F-S-S-V-D-R-T-G-L-D-E-S-W-D-T-I-L-S-E-L"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-E-A-I-I-A-K-K-A-E-Q-V-E-L-I-A-E-K-M-K-A-A-A-S-I-V-V-V-D-S-R-G-L-T-V-E-Q-D-T-N-L-R-R-S-L-R-E-S-D-V-E-F-K-V-I-K-N-S-I-L-T-R-A-A-E-K-A-G-L-E-D-L-K-E-L-F-V-G-P-S-A-V-A-F-S-N-E-D-V-I-A-P-A-K-V-I-S-D-F-A-K-D-A-E-A-L-E-I-K-G-G-S-V-D-G-K-F-T-S-V-E-E-I-N-A-L-A-K-L-P-N-K-E-G-M-L-S-M-L-L-S-V-L-Q-A-P-V-R-N-V-A-Y-A-V-K-A-V-A-E-K-D-E-E-V-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-N-I-E-N-I-I-A-E-I-K-E-A-T-I-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-A-A-A-A-G-G-E-A-A-A-A-K-D-S-F-D-V-E-L-T-A-A-G-D-K-K-V-G-V-I-K-V-V-R-E-I-T-G-E-G-L-K-E-A-K-A-I-V-D-N-A-P-S-V-I-K-E-G-A-S-E-A-E-A-N-E-I-K-E-K-L-E-A-A-G-A-S-V-T-L-K"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-N-N-Y-I-A-S-I-E-N-Y-P-Q-E-G-I-T-F-R-D-I-S-P-L-M-A-D-G-K-A-Y-S-Y-A-V-R-E-I-V-Q-Y-A-A-D-K-D-I-D-M-I-V-G-P-E-A-R-G-F-I-V-G-C-P-V-A-Y-A-L-G-I-G-F-A-P-V-R-K-P-G-K-L-P-R-E-V-I-S-A-D-Y-E-K-E-Y-G-L-D-T-L-T-M-H-A-D-A-I-K-P-G-Q-R-V-L-I-V-D-D-L-L-A-T-G-G-T-V-K-A-T-I-E-M-I-E-K-L-G-G-V-V-A-G-C-A-F-L-V-E-L-D-G-L-N-G-R-K-A-I-E-G-Y-D-T-K-V-L-M-N-F-P-G"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-I-T-L-F-L-S-P-S-C-T-S-C-R-K-A-R-A-W-L-S-K-H-E-V-A-F-E-E-H-N-I-I-T-S-P-L-N-K-E-E-L-L-Q-I-L-S-F-T-E-N-G-T-E-D-I-I-S-T-R-S-K-V-F-Q-K-L-A-I-D-V-D-E-L-S-T-S-S-L-M-E-L-I-S-E-N-P-S-L-L-R-R-P-I-I-L-D-K-K-R-M-Q-I-G-F-N-E-D-E-I-R-A-F-L-P-R-D-Y-R-K-Q-E-L-K-Q-A-T-I-R-A-E-I-E-G-K-H-D"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-E-V-K-T-L-A-N-I-K-S-A-I-K-R-A-E-L-N-V-K-Q-N-E-K-N-S-A-Q-K-S-A-M-R-T-A-I-K-A-F-E-A-N-P-S-E-E-L-Y-R-A-A-S-S-S-I-D-K-A-A-S-K-G-L-I-H-T-N-K-A-S-R-D-K-A-R-L-A-T-K-L-G"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-Q-L-T-V-Q-V-V-T-P-D-G-I-R-Y-D-H-H-A-S-L-I-T-V-R-T-P-D-G-E-M-G-I-L-P-G-H-I-N-L-I-A-P-L-N-V-H-Q-M-K-I-N-R-S-H-Q-E-G-V-D-W-V-A-V-N-G-G-I-I-E-V-N-E-D-Q-V-T-I-V-A-D-S-A-E-R-A-R-D-I-D-L-N-R-A-E-R-A-K-E-R-A-E-R-A-L-E-K-A-Q-T-T-Q-N-I-D-E-M-R-R-A-E-V-A-L-R-R-A-I-N-R-I-S-V-G-K-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-K-K-T-Q-A-L-I-E-Q-Y-S-K-S-L-V-E-V-A-I-E-H-K-I-V-E-K-I-Q-Q-E-V-A-A-L-I-D-I-F-E-T-S-E-L-E-G-V-L-S-S-L-A-V-S-H-D-E-K-Q-H-F-V-K-T-L-Q-T-S-C-S-T-Y-L-V-N-F-L-E-V-I-V-Q-N-E-R-E-A-L-L-Y-P-I-L-K-S-V-D-Q-E-L-I-K-V-N-G-Q-Y-P-I-Q-I-T-T-A-V-A-L-S-P-E-Q-K-E-R-L-F-D-I-A-K-T-K-L-A-L-P-N-G-Q-L-V-E-H-I-D-P-S-I-V-G-G-F-V-V-N-A-N-N-K-V-I-D-A-S-V-R-N-Q-L-H-Q-F-K-M-K-L-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-I-L-I-N-S-T-T-I-G-D-I-I-I-V-S-G-S-V-L-L-L-F-I-L-I-K-T-F-A-W-K-Q-I-T-G-I-F-E-A-R-E-Q-K-I-A-N-D-I-D-T-A-E-Q-A-R-Q-Q-A-E-A-F-A-T-K-R-E-E-E-L-S-N-A-K-T-E-A-N-Q-I-I-D-N-A-K-E-T-G-L-A-K-G-D-Q-I-I-S-E-A-K-T-E-A-D-R-L-K-E-K-A-H-Q-D-I-A-Q-N-K-A-E-A-L-A-D-V-K-G-E-V-A-D-L-T-V-L-L-A-E-K-I-M-V-S-N-L-D-K-E-A-Q-S-N-L-I-D-S-Y-I-K-K-L-G-D-A"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-L-Y-P-T-P-I-A-K-L-I-D-S-F-S-K-L-P-G-I-G-T-K-T-A-T-R-L-A-F-Y-T-I-G-M-S-D-E-D-V-N-E-F-A-K-N-L-L-A-A-K-R-E-L-T-Y-C-S-V-C-G-N-L-T-D-D-D-P-C-L-I-C-T-D-K-T-R-D-Q-S-V-I-L-V-V-E-D-S-K-D-V-S-A-M-E-K-I-Q-E-Y-N-G-L-Y-H-V-L-H-G-L-I-S-P-M-N-G-I-S-P-D-D-I-N-L-K-S-L-I-T-R-L-M-D-G-Q-V-T-E-V-I-V-A-T-N-A-T-A-D-G-E-A-T-S-M-Y-I-S-R-V-L-K-P-A-G-I-K-V-T-R-L-A-R-G-L-A-V-G-S-D-I-E-Y-A-D-E-V-T-L-L-R-A-I-E-N-R-T-E-L"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-I-I-E-G-Q-L-V-A-N-E-M-K-I-G-I-V-V-S-R-F-N-E-L-I-T-S-K-L-L-S-G-A-V-D-G-L-L-R-H-G-V-S-E-E-D-I-D-I-V-W-V-P-G-A-F-E-I-P-Y-M-A-R-K-M-A-L-Y-K-D-Y-D-A-I-I-C-L-G-V-V-I-K-G-S-T-D-H-Y-D-Y-V-C-N-E-V-T-K-G-I-G-H-L-N-S-Q-S-D-I-P-H-I-F-G-V-L-T-T-D-N-I-E-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-Y-D-C-A-L-S-A-I-E-M-V-N-L-D-K-K-L-R-E-R"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-N-I-V-L-V-G-R-M-T-K-D-A-E-L-R-Y-T-P-S-N-Q-A-V-A-T-F-S-L-A-V-N-R-N-F-K-N-Q-S-G-E-R-E-A-D-F-I-N-C-V-I-W-R-Q-Q-A-E-N-L-A-N-W-A-K-K-G-A-L-V-G-I-T-G-R-I-Q-T-R-N-Y-E-N-Q-Q-G-Q-R-I-Y-V-T-E-V-V-A-E-N-F-Q-L-L-E-S-R-N-S-Q-Q-Q-T-N-Q-S-G-N-S-S-N-S-Y-F-G-N-A-N-K-M-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-P-L-I-Q-S-L-T-E-G-Q-L-R-S-D-I-P-E-F-R-A-G-D-T-V-R-V-H-A-K-V-V-E-G-T-R-E-R-I-Q-I-F-E-G-V-V-I-S-R-K-G-Q-G-I-S-E-M-Y-T-V-R-K-I-S-G-G-I-G-V-E-R-T-F-P-I-H-T-P-R-V-D-K-I-E-V-V-R-Y-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-Q-G-K-A-A-R-I-K-E-I-R-R"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-T-Y-R-V-K-S-D-K-D-F-Q-M-I-F-S-R-G-K-N-V-A-N-R-K-F-V-I-Y-Y-L-E-K-E-Q-K-H-F-R-V-G-I-S-V-S-K-K-L-G-N-A-V-V-R-N-A-I-K-R-K-I-R-H-V-L-L-S-Q-K-T-A-L-Q-D-Y-D-F-V-V-I-A-R-K-G-V-E-E-L-D-Y-Q-A-L-E-K-N-L-I-H-V-L-K-I-A-G-L-I"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-A-S-I-I-Y-S-P-K-D-I-F-E-Q-D-F-K-V-S-M-R-G-Y-D-K-K-E-V-D-V-F-L-D-D-V-I-K-D-Y-E-N-Y-L-E-Q-I-E-K-L-Q-M-E-N-R-R-L-Q-Q-A-L-D-K-K-E-S-E-A-S-N-V-R-N-S-G-T-A-M-Y-N-Q-K-P-I-A-Q-S-A-T-N-F-D-I-L-K-R-I-S-R-L-E-K-E-V-F-G-R-Q-I-R-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-N-E-I-I-A-Q-Y-A-R-H-E-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-W-E-I-N-H-L-N-D-H-I-K-Q-H-K-K-D-H-A-T-Y-R-G-L-M-K-K-I-G-H-R-R-N-L-L-A-Y-L-R-R-T-D-V-N-R-Y-R-E-L-I-Q-S-L-G-L-R-R"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-Y-N-K-V-I-M-I-G-R-L-T-A-K-P-E-M-V-K-T-P-T-D-K-S-V-T-R-A-T-V-A-V-N-R-R-F-K-G-S-N-G-E-R-E-A-D-F-I-N-V-V-M-W-G-R-L-A-E-T-L-A-S-Y-G-T-K-G-S-L-I-S-I-D-G-E-L-R-T-R-K-Y-E-K-D-G-Q-T-H-Y-I-T-E-V-L-A-S-S-F-Q-L-L-E-S-R-A-Q-R-A-M-R-E-N-N-V-S-G-D-L-S-D-L-V-L-E-E-E-E-L-P-F"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-E-L-E-V-F-A-G-Q-E-K-S-E-L-S-M-I-E-V-A-R-A-I-L-E-Q-R-G-R-D-N-E-M-Y-F-S-D-L-V-N-D-I-Q-T-Y-L-G-K-S-D-S-A-I-R-E-S-L-P-F-F-Y-S-D-L-N-T-D-G-S-F-I-P-L-G-E-N-K-W-G-L-R-S-W-Y-A-I-D-E-I-D-E-E-I-I-T-L-E-E-D-E-D-G-A-P-K-R-K-K-K-R-V-N-A-F-M-D-G-D-E-D-A-I-D-Y-N-D-D-D-P-E-D-E-D-F-T-E-E-T-P-S-L-E-Y-D-E-E-N-P-D-D-E-K-S-E-V-E-S-Y-D-S-E-I-N-E-I-I-P-D-E-D-L-D-E-D-V-E-I-N-E-E-D-D-E-E-E-E-E-E-E-E-V"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-V-F-N-K-L-F-K-R-R-H-S-V-S-E-E-I-K-K-D-D-L-Q-E-E-V-E-A-T-E-T-E-E-T-V-E-E-V-I-E-E-I-P-E-K-S-E-L-E-L-A-N-E-R-A-D-E-F-E-N-K-Y-L-R-A-H-A-E-M-Q-N-I-Q-R-R-S-S-E-E-R-Q-Q-L-Q-R-Y-R-S-Q-D-L-A-K-A-I-L-P-S-L-D-N-L-E-R-A-L-A-V-E-G-L-T-D-D-V-K-K-G-L-E-M-T-R-D-S-L-I-Q-A-L-K-E-E-G-V-E-E-V-E-V-D-S-F-D-H-N-F-H-M-A-V-Q-T-L-P-A-D-D-E-H-P-A-D-S-I-A-E-V-F-Q-K-G-Y-K-L-H-E-R-L-L-R-P-A-M-V-V-V-Y-N"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-E-G-S-R-K-V-R-N-R-V-G-R-G-T-S-S-G-N-G-K-T-S-G-R-G-Q-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-M-P-K-R-G-F-S-N-I-N-A-K-E-Y-A-L-V-N-L-D-Q-L-N-V-F-E-D-G-T-E-V-T-P-V-V-L-K-E-A-G-I-V-R-A-E-K-S-G-V-K-I-L-G-N-G-E-L-T-K-K-L-S-V-K-A-A-K-F-S-K-S-A-E-A-A-I-T-A-K-G-G-S-I-E-V-I"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-F-K-D-N-A-V-E-L-E-E-R-V-V-A-I-N-R-V-T-K-V-V-K-G-G-R-R-L-R-F-A-A-L-V-V-V-G-D-R-N-G-R-V-G-F-G-T-G-K-A-Q-E-V-P-E-A-I-R-K-A-V-E-A-A-K-K-N-M-V-E-V-P-M-V-G-T-T-I-P-H-E-V-R-S-E-F-G-G-A-K-V-L-L-K-P-A-V-E-G-A-G-V-A-A-G-G-A-V-R-A-V-I-E-L-A-G-V-A-D-I-T-S-K-S-L-G-S-N-T-P-I-N-I-V-R-A-T-V-E-G-L-K-Q-L-K-R-A-E-E-V-A-A-L-R-G-I-S-V-S-D-L-A"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-I-R-Q-K-R-H-R-R-V-R-G-K-L-S-G-T-A-D-R-P-R-L-N-I-F-R-S-N-T-G-I-Y-A-Q-V-I-D-D-V-A-G-V-T-L-A-S-A-S-T-L-D-K-E-V-S-N-G-T-K-T-E-Q-A-V-V-V-G-K-L-V-A-E-R-A-V-A-K-G-I-S-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-D-S-A-R-E-N-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-V-I-T-L-P-A-G-V-E-I-I-N-K-D-N-V-V-T-V-K-G-P-K-G-Q-L-T-R-E-F-N-K-N-I-G-I-T-V-E-G-T-E-V-T-V-T-R-P-N-D-S-K-E-M-K-T-I-H-G-T-T-R-A-N-L-N-N-M-V-V-G-V-S-E-G-F-K-K-A-L-E-M-R-G-V-G-Y-R-A-Q-L-Q-G-S-K-L-V-L-S-V-G-K-S-H-Q-D-E-V-E-A-P-E-G-V-T-F-E-V-P-T-P-T-T-I-N-V-I-G-I-N-K-E-S-V-G-Q-T-A-A-Y-V-R-S-L-R-S-P-E-P-Y-K-G-K-G-I-R-Y-V-G-E-F-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-F-L-T-R-I-R-N-A-N-Q-A-K-H-E-V-L-E-V-P-A-S-N-I-K-K-G-I-A-D-I-L-K-R-E-G-F-V-K-N-V-E-V-I-E-D-D-K-Q-G-I-I-R-V-F-L-K-Y-G-Q-N-G-E-R-V-I-T-N-L-K-R-I-S-K-P-G-L-R-V-Y-T-K-H-E-D-M-P-K-V-L-N-G-L-G-I-A-I-V-S-T-S-E-G-L-L-T-D-K-E-A-R-Q-K-N-I-G-G-E-V-L-A-Y-I-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-N-K-R-P-A-K-F-S-T-Q-A-Y-T-R-C-E-K-C-G-R-P-H-S-V-Y-R-K-F-Q-L-C-R-V-C-F-R-D-L-A-Y-K-G-Q-V-P-G-V-T-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-N-R-L-K-E-K-Y-T-N-E-V-V-P-A-L-T-E-K-F-N-Y-S-S-V-M-A-V-P-K-V-E-K-I-V-L-N-M-G-V-G-D-A-V-S-N-A-K-N-L-E-K-A-A-A-E-L-A-L-I-S-G-Q-K-P-L-I-T-K-A-K-K-S-I-A-G-F-R-L-R-E-G-V-A-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-V-S-V-S-L-P-R-V-R-D-F-H-G-V-P-T-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-N-F-D-D-V-D-K-V-R-G-L-D-I-V-I-V-T-T-A-N-T-D-E-E-S-R-E-L-L-K-G-L-G-M-P-F-A-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-F-V-K-K-G-D-K-V-R-V-I-A-G-K-D-K-G-T-E-A-V-V-L-K-A-L-P-K-V-N-K-V-V-V-E-G-V-A-L-I-K-K-H-Q-K-P-N-N-E-N-P-Q-G-A-I-V-E-K-E-A-P-I-H-V-S-N-V-Q-V-L-D-K-N-G-V-A-G-R-V-G-Y-K-V-V-D-G-K-K-V-R-Y-N-K-K-S-G-E-V-L-D"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-K-V-A-D-N-S-G-A-R-E-I-L-T-I-K-V-L-G-G-S-G-R-K-F-A-N-I-G-D-V-I-V-A-S-V-K-Q-A-T-P-G-G-A-V-K-K-G-D-V-V-K-A-V-I-V-R-T-K-T-G-A-R-R-P-D-G-S-Y-I-K-F-D-D-N-A-A-V-I-I-R-D-D-K-T-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-G-Y-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-N-Q-R-K-T-L-Y-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-K-R-N-H-P-V-Y-G-K-R-I-N-Y-S-K-K-Y-K-A-H-D-E-N-N-V-A-K-E-G-D-I-V-R-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-V-V-E-K-A-V-I-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-H-R-R-E-F-R-G-K-M-R-G-E-A-K-G-G-K-E-V-S-F-G-E-Y-G-L-Q-A-T-T-S-H-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-A-K-A-I-G-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-P-V-K-R-G-K-V-M-F-E-I-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-C-K-F-V-K-R-E-A-E"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-E-I-T-S-A-K-A-M-A-R-T-V-R-V-S-P-R-K-T-R-L-V-L-D-L-I-R-G-K-N-V-A-D-A-I-A-I-L-K-F-T-P-N-K-A-A-R-V-I-E-K-T-L-N-S-A-I-A-N-A-E-N-N-F-G-L-E-K-A-N-L-V-V-S-E-T-F-A-N-E-G-P-T-M-K-R-F-R-P-R-A-K-G-S-A-S-P-I-N-K-R-T-T-H-V-T-V-V-V-S-E-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-K-M-I-V-G-L-G-N-P-G-S-K-Y-N-D-T-K-H-N-I-G-F-M-A-V-D-R-I-V-K-D-L-D-V-N-F-T-E-D-K-N-F-K-A-E-I-G-S-D-F-I-N-G-E-K-I-Y-F-I-K-P-T-T-F-M-N-N-S-G-I-A-V-K-A-L-L-T-Y-Y-N-I-S-I-K-D-M-I-I-I-Y-D-D-L-D-M-E-V-G-K-I-R-F-R-Q-K-G-S-A-G-G-H-N-G-I-K-S-I-I-A-H-L-G-T-Q-E-F-D-R-I-K-V-G-I-G-R-P-N-G-R-M-T-V-I-N-H-V-L-G-K-F-D-K-N-D-E-I-M-I-L-N-T-L-D-K-V-D-N-A-V-N-Y-Y-L-Q-T-N-D-F-Q-K-T-M-Q-K-Y-N-G-L-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-Q-D-V-K-G-K-G-K-K-G-E-V-K-E-V-P-T-G-Y-A-Q-N-F-L-L-K-K-N-L-A-K-E-A-T-T-Q-A-I-G-E-L-K-G-K-Q-K-S-E-E-K-A-Q-A-E-I-L-A-Q-A-K-E-L-K-T-Q-L-E-S-E-T-T-R-V-Q-F-I-E-K-V-G-P-D-G-R-T-F-G-S-I-T-A-K-K-I-A-E-E-L-Q-K-Q-Y-G-I-K-I-D-K-R-H-I-D-L-D-H-T-I-R-A-I-G-K-V-E-V-P-V-K-L-H-K-Q-V-S-S-Q-I-K-L-D-I-K-E-A"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-D-Y-I-K-G-K-L-S-K-I-T-A-K-F-I-V-V-E-T-A-G-L-G-Y-M-I-Y-V-A-N-P-Y-S-F-S-G-Y-V-N-Q-E-V-T-I-Y-L-H-Q-V-I-R-D-D-A-H-L-L-F-G-F-H-T-E-N-E-K-E-I-F-L-N-L-I-S-V-S-G-I-G-P-T-T-A-L-A-I-I-A-V-D-D-N-E-G-L-V-S-A-I-D-N-S-D-I-K-Y-L-T-K-F-P-K-I-G-K-K-T-A-Q-Q-M-I-L-D-L-S-G-K-F-V-E-A-S-G-E-S-A-T-S-R-K-V-S-S-E-Q-N-S-N-L-E-E-A-M-E-A-L-L-A-L-G-Y-K-A-T-E-L-K-K-V-K-A-F-F-E-G-T-N-E-T-V-E-Q-Y-I-K-S-S-L-K-M-L-M-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-K-P-R-K-S-K-V-E-K-S-D-S-P-A-L-N-I-G-Y-N-S-H-R-K-V-H-T-K-L-S-A-P-Q-K-R-G-V-A-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-F-A-R-V-R-L-S-N-L-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-T-A-G-V-A-D-R-K-Q-G-R-S-K-Y-G-A-K-R-P-K-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-N-Q-A-P-K-R-E-V-L-P-D-P-L-Y-N-S-K-I-V-T-R-L-I-N-R-V-M-L-D-G-K-R-G-T-A-A-T-I-V-Y-D-A-F-E-A-I-K-E-A-T-G-T-D-A-L-E-V-F-E-T-A-M-E-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-S-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-N-A-S-R-A-R-G-E-H-T-M-K-D-R-L-A-K-E-I-M-D-A-A-N-N-T-G-A-S-V-K-K-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-F-R-W"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-F-Y-Q-E-T-K-E-R-N-P-R-R-E-Q-T-K-T-L-Y-V-T-I-D-A-A-N-E-L-E-G-R-I-A-A-R-K-L-V-E-E-N-T-A-Y-N-I-E-F-I-E-L-L-S-D-K-H-L-E-Y-E-K-E-T-G-V-F-E-L-T-E-F"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-F-Q-K-Q-Q-K-L-V-E-Q-Y-A-E-L-R-R-E-L-K-E-K-G-D-Y-E-A-L-R-K-L-P-K-D-S-N-P-N-R-L-K-N-R-D-L-I-D-G-R-P-H-A-Y-M-R-K-F-G-M-S-R-I-N-F-R-N-L-A-Y-K-G-Q-I-P-G-I-K-K-A-S-W"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Q-Q-R-R-G-G-F-K-R-R-K-K-V-D-Y-I-A-A-N-K-I-E-Y-V-D-Y-K-D-T-E-L-L-S-R-F-V-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-N-Q-R-K-V-T-T-A-I-K-R-A-R-V-M-A-L-M-P-Y-V-N-E-D"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-K-I-S-E-E-E-V-R-H-V-A-N-L-S-K-L-R-F-S-D-Q-E-T-K-E-F-A-S-S-L-S-K-I-V-D-M-I-E-L-L-N-E-V-D-T-E-G-V-P-V-T-T-T-M-A-D-R-K-T-V-M-R-E-D-I-A-Q-P-G-N-N-R-D-D-L-F-K-N-V-P-Q-H-Q-D-Y-Y-I-K-V-P-A-I-L-E-D-G-G-D-A"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-K-C-G-Y-N-K-S-S-V-V-D-S-R-Q-A-E-E-G-T-T-I-R-R-R-R-E-C-E-K-C-G-N-R-F-T-T-F-E-R-L-E-E-L-P-L-L-V-I-K-K-D-G-T-R-E-Q-F-S-R-D-K-I-L-N-G-I-I-Q-S-A-Q-K-R-P-V-S-S-E-D-I-E-N-C-I-L-R-I-E-R-K-I-R-S-E-Y-E-D-E-V-S-S-I-T-I-G-N-L-V-M-D-E-L-A-E-L-D-E-I-T-Y-V-R-F-A-S-V-Y-K-S-F-K-D-V-D-E-I-E-E-L-L-Q-Q-I-T-K-R-V-R-S-K-K-S-G-S-V"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-E-K-T-Y-P-M-T-Q-V-E-K-D-Q-L-E-K-E-L-E-E-L-K-L-V-R-R-P-E-V-V-E-R-I-K-I-A-R-S-Y-G-D-L-S-E-N-S-E-Y-D-A-A-K-D-E-Q-A-F-V-E-G-Q-I-Q-I-L-E-T-K-I-R-Y-A-E-I-I-D-S-D-A-V-A-K-D-E-V-A-I-G-K-T-V-L-V-Q-E-V-G-T-N-D-K-D-T-Y-H-I-V-G-A-A-G-A-D-I-F-S-G-K-I-S-N-E-S-P-I-A-H-A-L-I-G-K-K-T-G-D-L-A-T-I-E-S-P-A-G-S-Y-Q-V-E-I-I-S-V-E-K-T-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-S-F-L-I-F-L-V-R-F-Y-Q-K-N-I-S-P-A-F-P-A-S-C-R-Y-C-P-T-C-S-T-Y-M-I-E-A-I-Q-K-H-G-L-K-G-V-L-M-G-I-A-R-I-L-R-C-H-P-L-A-H-G-G-N-D-P-V-P-D-H-F-S-L-R-R-N-K-T-D-I-S-D"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-I-P-V-V-I-E-Q-T-S-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-T-G-Q-V-E-D-N-M-A-N-S-I-I-A-Q-L-L-F-L-D-A-Q-D-N-T-K-D-I-Y-L-Y-V-N-T-P-G-G-S-V-S-A-G-L-A-I-V-D-T-M-N-F-I-K-S-D-V-Q-T-I-V-M-G-M-A-A-S-M-G-T-I-I-A-S-S-G-A-K-G-K-R-F-M-L-P-N-A-E-Y-M-I-H-Q-P-M-G-G-T-G-G-G-T-Q-Q-S-D-M-A-I-A-A-E-H-L-L-K-T-R-H-T-L-E-K-I-L-A-D-N-S-G-Q-S-I-E-K-V-H-D-D-A-E-R-D-R-W-M-S-A-Q-E-T-L-D-Y-G-F-I-D-A-I-M-E-N-N-N-L-Q"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-K-L-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-I-N-I-M-G-F-T-K-E-F-N-A-R-T-A-D-Q-A-G-M-I-I-P-V-V-I-S-V-Y-E-D-K-S-F-D-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-E-K-G-S-G-E-P-N-K-T-K-V-A-T-V-T-R-A-Q-V-Q-E-I-A-E-T-K-M-P-D-L-N-A-A-N-L-E-S-A-M-R-M-I-E-G-T-A-R-S-M-G-F-T-V-T-D"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-R-A-I-F-A-G-G-C-F-W-C-M-V-Q-P-F-E-E-L-D-G-I-E-S-V-L-S-G-Y-T-G-G-H-V-E-N-P-T-Y-K-E-V-C-S-K-T-T-G-H-T-E-A-V-E-I-I-F-N-P-E-K-I-S-Y-A-N-L-V-E-L-Y-W-A-Q-T-D-P-T-D-A-F-G-Q-F-E-D-R-G-D-N-Y-R-P-V-I-F-Y-E-N-E-E-Q-R-Q-I-A-Q-K-S-K-D-K-L-Q-A-S-G-R-F-D-R-P-I-V-T-S-I-E-P-A-D-T-F-Y-P-A-E-D-Y-H-Q-A-F-Y-R-T-N-P-A-R-Y-A-L-S-S-A-R-R-H-A-F-L-E-E-N-W-H"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-T-Y-A-I-I-K-T-G-G-K-Q-V-K-V-E-V-G-Q-A-I-Y-V-E-K-L-D-V-E-A-G-A-E-V-T-F-N-E-V-V-L-V-G-G-E-T-T-K-V-G-T-P-V-V-E-G-A-T-V-V-G-T-V-E-K-Q-G-K-Q-K-K-V-V-S-Y-K-Y-K-P-K-K-G-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-N-A-I-N-A"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-K-R-K-E-I-I-D-D-V-T-M-K-R-A-I-T-R-I-T-Y-E-I-I-E-R-N-K-N-L-D-N-I-V-L-A-G-I-K-T-R-G-V-F-L-A-K-R-I-Q-E-R-L-K-Q-L-E-N-L-D-I-P-V-G-E-L-D-T-K-P-F-R-D-D-M-K-V-E-V-D-T-T-T-M-P-V-D-I-T-D-K-D-I-I-L-I-D-D-V-L-Y-T-G-R-T-I-R-A-A-I-D-N-L-V-S-L-G-R-P-S-R-V-S-L-A-V-L-I-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-Q-F-E-E-I-L-V-E-V-M-E-H-D-G-Y-D-R-V-S-I-I-D-P-S"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-Y-F-N-V-G-K-I-V-N-T-Q-G-L-Q-G-E-M-R-V-L-S-V-T-D-F-V-E-E-R-F-K-K-G-Q-V-L-A-L-F-D-E-K-N-Q-F-V-M-D-I-E-I-A-S-H-R-K-Q-K-N-F-D-I-I-K-F-K-G-M-Y-H-I-N-D-I-E-K-Y-K-G-F-T-L-K-V-A-E-D-Q-L-S-D-L-K-D-G-E-F-Y-Y-H-E-I-I-G-L-D-V-Y-E-G-E-E-L-I-G-K-I-K-E-I-L-Q-P-G-A-N-D-V-W-V-V-E-R-H-G-K-R-D-L-L-L-P-Y-I-P-P-V-V-L-E-V-D-L-S-N-Q-R-V-Q-V-E-L-M-E-G-L-D-D-E-D"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-A-E-E-F-L-N-T-H-N-A-S-I-L-L-S-A-A-N-K-S-H-Y-P-Q-D-D-L-P-E-V-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-L-L-G-R-K-N-L-A-R-T-S-S-K-P-G-K-T-Q-L-L-N-F-Y-N-I-D-D-K-L-R-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-T-E-R-A-K-W-G-K-M-I-E-E-Y-L-V-T-R-D-N-L-R-V-V-V-S-L-V-D-F-R-H-D-P-S-A-D-D-I-Q-I-Y-E-F-L-K-Y-Y-E-I-P-V-I-I-V-A-T-K-A-D-K-I-P-R-G-K-W-N-K-H-E-S-S-I-K-K-K-L-N-F-D-K-K-D-H-F-I-V-F-S-S-V-D-R-T-G-L-D-E-S-W-D-T-I-L-S-E-L"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-E-A-I-I-A-K-K-A-E-Q-V-E-L-I-A-E-K-M-K-A-A-A-S-I-V-V-V-D-S-R-G-L-T-V-E-Q-D-T-N-L-R-R-S-L-R-E-S-D-V-E-F-K-V-I-K-N-S-I-L-I-R-A-A-E-K-A-G-L-E-D-L-K-E-L-F-V-G-P-S-A-V-A-F-S-N-E-D-V-I-A-P-A-K-V-I-S-D-F-A-K-D-A-E-A-L-E-I-K-G-G-S-V-D-G-K-F-T-S-V-E-E-I-N-A-L-A-K-L-P-N-K-E-G-M-L-S-M-L-L-S-V-L-Q-A-P-V-R-N-V-A-Y-A-V-K-A-V-A-E-K-D-E-E-V-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-N-I-E-N-I-I-A-E-I-K-E-A-T-I-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-A-A-A-A-S-G-E-A-A-A-A-K-D-S-F-D-V-E-L-T-A-A-G-D-K-K-V-G-V-I-K-V-V-R-E-I-T-G-E-G-L-K-E-A-K-A-I-V-D-N-A-P-S-V-I-K-E-G-A-S-E-A-E-A-N-E-I-K-E-K-L-E-A-A-G-A-S-V-T-L-K"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-N-N-Y-I-A-S-I-E-N-Y-P-Q-E-G-I-T-F-R-D-I-S-P-L-M-A-D-G-K-A-Y-S-Y-A-V-R-E-I-V-Q-Y-A-A-D-K-D-I-D-M-I-V-G-P-E-A-R-G-F-I-V-G-C-P-V-A-Y-A-L-G-I-G-F-A-P-V-R-K-P-G-K-L-P-R-E-V-I-S-A-D-Y-E-K-E-Y-G-L-D-T-L-T-M-H-A-D-A-I-K-P-G-Q-R-V-L-I-V-D-D-L-L-A-T-G-G-T-V-K-A-T-I-E-M-I-E-K-L-G-G-V-V-A-G-C-A-F-L-V-E-L-D-G-L-N-G-R-K-A-I-E-G-Y-D-T-K-V-L-M-N-F-P-G"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-I-T-L-F-L-S-P-S-C-T-S-C-R-K-A-R-A-W-L-S-K-H-E-V-A-F-E-E-H-N-I-I-T-S-P-L-N-K-E-E-L-L-Q-I-L-S-F-T-E-N-G-T-E-D-I-I-S-T-R-S-K-V-F-Q-K-L-A-I-D-V-D-E-L-S-T-S-S-L-M-E-L-I-S-E-N-P-S-L-L-R-R-P-I-I-L-D-K-K-R-M-Q-I-G-F-N-E-D-E-I-R-A-F-L-P-R-D-Y-R-K-Q-E-L-K-Q-A-T-I-R-A-E-I-E-G-K-H-D"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-A-E-L-N-V-K-Q-N-E-K-N-S-A-Q-K-S-A-M-R-T-A-I-K-A-F-E-A-N-P-S-E-E-L-Y-R-A-A-S-S-S-I-D-K-A-A-S-K-G-L-I-H-T-N-K-A-S-R-D-K-A-R-L-A-T-K-L-G"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-Q-L-T-V-Q-V-V-T-P-D-G-I-R-Y-D-H-H-A-S-L-I-T-V-R-T-P-D-G-E-M-G-I-L-P-G-H-I-N-L-I-A-P-L-I-V-H-Q-M-K-I-N-R-S-H-Q-E-G-V-D-W-V-A-V-N-G-G-I-I-E-V-N-E-D-Q-V-T-I-V-A-D-S-A-E-R-A-R-D-I-D-L-N-R-A-E-R-A-K-E-R-A-E-R-A-L-E-K-A-Q-T-T-Q-N-I-D-E-M-R-R-A-E-V-A-L-R-R-A-I-N-R-I-S-V-G-K-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-K-K-T-Q-A-L-I-E-Q-Y-S-K-S-L-V-E-V-A-I-E-H-K-I-V-E-K-I-Q-Q-E-V-A-A-L-I-D-I-F-E-T-S-E-L-E-G-V-L-S-S-L-A-V-S-H-D-E-K-Q-H-F-V-K-T-L-Q-T-S-C-S-T-Y-L-V-N-F-L-E-V-I-V-Q-N-E-R-E-A-L-L-Y-P-I-L-K-S-V-D-Q-E-L-I-K-V-N-G-Q-Y-P-I-Q-I-T-T-A-V-A-L-S-P-E-Q-K-E-R-L-F-D-I-A-K-T-K-L-A-L-P-N-G-Q-L-V-E-H-I-D-P-S-I-V-G-G-F-V-V-N-A-N-N-K-V-I-D-A-S-V-R-N-Q-L-H-Q-F-K-M-K-L-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-I-L-I-N-S-T-T-I-G-D-I-I-I-V-S-G-S-V-L-L-L-F-I-L-I-K-T-F-A-W-K-Q-I-T-G-I-F-E-A-R-E-Q-K-I-A-N-D-I-D-T-A-E-Q-A-R-Q-Q-A-E-A-F-A-T-K-R-E-E-E-L-S-N-A-K-T-E-A-N-Q-I-I-D-N-A-K-E-T-G-L-A-K-G-D-Q-I-I-S-E-A-K-T-E-A-D-R-L-K-E-K-A-H-Q-D-I-A-Q-N-K-A-E-A-L-A-D-V-K-G-E-V-A-D-L-T-V-L-L-A-E-K-I-M-V-S-N-L-D-K-E-A-Q-S-N-L-I-D-S-Y-I-K-K-L-G-D-A"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-L-Y-P-T-P-I-A-K-L-I-D-S-F-S-K-L-P-G-I-G-T-K-T-A-T-R-L-A-F-Y-T-I-G-M-S-D-E-D-V-N-E-F-A-K-N-L-L-A-A-K-R-E-L-T-Y-C-S-V-C-G-N-L-T-D-D-D-P-C-L-I-C-T-D-K-T-R-D-Q-S-V-I-L-V-V-E-D-S-K-D-V-S-A-M-E-K-I-Q-E-Y-N-G-L-Y-H-V-L-H-G-L-I-S-P-M-N-G-I-S-P-D-D-I-N-L-K-S-L-I-T-R-L-M-D-G-Q-V-T-E-V-I-V-A-T-N-A-T-A-D-G-E-A-T-S-M-Y-I-S-R-V-L-K-P-A-G-I-K-V-T-R-L-A-R-G-L-A-V-G-S-D-I-E-Y-A-D-E-V-T-L-L-R-A-I-E-N-R-T-E-L"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-I-I-E-G-Q-L-V-A-N-E-M-K-I-G-I-V-V-S-R-F-N-E-L-I-T-S-K-L-L-S-G-A-V-D-G-L-L-R-H-G-V-S-E-E-D-I-D-I-V-W-V-P-G-A-F-E-I-P-Y-M-A-R-K-M-A-L-Y-K-D-Y-D-A-I-I-C-L-G-V-V-I-K-G-S-T-D-H-Y-D-Y-V-C-N-E-V-T-K-G-I-G-H-L-N-S-Q-S-D-I-P-H-I-F-G-V-L-T-T-D-N-I-E-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-Y-D-C-A-L-S-A-I-E-M-V-N-L-D-K-K-L-R-E-R"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-P-L-I-Q-S-L-T-E-G-Q-L-R-S-D-I-P-E-F-R-A-G-D-T-V-R-V-H-A-K-V-V-E-G-T-R-E-R-I-Q-I-F-E-G-V-V-I-S-R-K-G-Q-G-I-S-E-M-Y-T-V-R-K-I-S-G-G-I-G-V-E-R-T-F-P-I-H-T-P-R-V-D-K-I-E-V-V-R-Y-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-Q-G-K-A-A-R-I-K-E-I-R-R"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-T-Y-R-V-K-S-D-K-D-F-Q-M-I-F-S-R-G-K-N-V-A-N-R-K-F-V-I-Y-Y-L-E-K-E-Q-K-H-F-R-V-G-I-S-V-S-K-K-L-G-N-A-V-V-R-N-A-I-K-R-K-I-R-H-V-L-L-S-Q-K-T-A-L-Q-D-Y-D-F-V-V-I-A-R-K-G-V-E-E-L-N-Y-Q-A-L-E-K-N-L-I-H-V-L-K-I-A-G-L-I"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-A-S-I-I-Y-S-P-K-D-I-F-E-Q-D-F-K-V-S-M-R-G-Y-D-K-K-E-V-D-V-F-L-D-D-V-I-K-D-Y-E-N-Y-L-E-Q-I-E-K-L-Q-M-E-N-R-R-L-Q-Q-A-L-D-K-K-E-S-E-A-S-N-V-R-N-S-G-T-A-M-Y-N-Q-K-P-I-A-Q-S-A-T-N-F-D-I-L-K-R-I-S-R-L-E-K-E-V-F-G-R-Q-I-R-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-N-E-I-I-A-Q-Y-A-R-H-E-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-W-E-I-N-H-L-N-D-H-I-K-Q-H-K-K-D-H-A-T-Y-R-G-L-M-K-K-I-G-H-R-R-N-L-L-A-Y-L-R-R-T-D-V-N-R-Y-R-E-L-I-Q-S-L-G-L-R-R"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-Y-N-K-V-I-M-I-G-R-L-T-A-K-P-E-M-V-K-T-P-T-D-K-S-V-T-R-A-T-V-A-V-N-R-R-F-K-G-S-N-G-E-R-E-A-D-F-I-N-V-V-M-W-G-R-L-A-E-T-L-A-S-Y-G-T-K-G-S-L-I-S-V-D-G-E-L-R-T-R-K-Y-E-K-D-G-Q-T-H-Y-I-T-E-V-L-A-S-S-F-Q-L-L-E-S-R-S-Q-R-A-M-R-E-N-N-I-S-G-D-L-S-D-L-V-L-E-E-E-E-L-P-F"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-E-L-E-V-F-A-G-Q-E-K-S-E-L-S-M-I-E-V-A-R-A-I-L-E-Q-R-G-R-D-N-E-M-Y-F-S-D-L-V-N-D-I-Q-T-Y-L-G-K-S-D-S-A-I-R-E-S-L-P-F-F-Y-S-D-L-N-T-D-G-S-F-I-P-L-G-E-N-K-W-G-L-R-S-W-Y-A-I-D-E-I-D-E-E-I-I-T-L-E-E-D-E-D-G-A-P-K-R-K-K-K-R-V-N-A-F-M-D-G-D-E-D-A-I-D-Y-N-D-D-D-P-E-D-E-D-F-T-E-E-T-P-S-L-E-Y-D-E-E-N-P-D-D-E-K-S-E-V-E-S-Y-D-S-E-I-N-E-I-I-P-D-E-D-L-D-E-D-V-E-I-N-E-E-D-D-E-E-E-E-E-E-E-E-V"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-V-F-N-K-L-F-K-R-R-H-S-V-S-E-E-I-K-K-D-D-L-Q-E-E-V-E-A-T-E-T-E-E-T-V-E-E-V-I-E-E-I-P-E-K-S-E-L-E-L-A-N-E-R-A-D-E-F-E-N-K-Y-L-R-A-H-A-E-M-Q-N-I-Q-R-R-S-S-E-E-R-Q-Q-L-Q-R-Y-R-S-Q-D-L-A-K-A-I-L-P-S-L-D-N-L-E-R-A-L-A-V-E-G-L-T-D-D-V-K-K-G-L-E-M-T-R-D-S-L-I-Q-A-L-K-E-E-G-V-E-E-V-E-V-D-S-F-D-H-N-F-H-M-A-V-Q-T-L-P-A-D-D-E-H-P-A-D-S-I-A-E-V-F-Q-K-G-Y-K-L-H-E-R-L-L-R-P-A-M-V-V-V-Y-N"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-E-G-S-R-K-V-R-N-R-V-G-R-G-T-S-S-G-N-G-K-T-S-G-R-G-Q-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-M-P-K-R-G-F-S-N-I-N-A-K-E-Y-A-L-V-N-L-D-Q-L-N-V-F-E-D-G-T-E-V-T-P-V-V-L-K-E-A-G-I-V-R-A-E-K-S-G-V-K-I-L-G-N-G-E-L-T-K-K-L-S-V-K-A-A-K-F-S-K-S-A-E-A-A-I-T-A-K-G-G-S-I-E-V-I"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-F-K-D-N-A-V-E-L-E-E-R-V-V-A-I-N-R-V-T-K-V-V-K-G-G-R-R-L-R-F-A-A-L-V-V-V-G-D-R-N-G-R-V-G-F-G-T-G-K-A-Q-E-V-P-E-A-I-R-K-A-V-E-A-A-K-K-N-M-V-E-V-P-M-V-G-T-T-I-P-H-E-V-R-S-E-F-G-G-A-K-V-L-L-K-P-A-V-E-G-A-G-V-A-A-G-G-A-V-R-A-V-I-E-L-A-G-V-A-D-I-T-S-K-S-L-G-S-N-T-P-I-N-I-V-R-A-T-V-E-G-L-K-Q-L-K-R-A-E-E-V-A-A-L-R-G-I-S-V-S-D-L-A"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-I-R-Q-K-R-H-R-R-V-R-G-K-L-S-G-T-A-D-R-P-R-L-N-I-F-R-S-N-T-G-I-Y-A-Q-V-I-D-D-V-A-G-V-T-L-A-S-A-S-T-L-D-K-E-V-S-N-G-T-K-T-E-Q-A-V-V-V-G-K-L-V-A-E-R-A-V-A-K-G-I-S-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-D-S-A-R-E-N-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-V-I-T-L-P-A-G-V-E-I-I-N-K-D-N-V-V-T-V-K-G-P-K-G-E-L-T-R-E-F-N-K-N-I-G-I-T-V-E-G-T-E-V-T-V-T-R-P-N-D-S-K-E-M-K-T-I-H-G-T-T-R-A-N-L-N-N-M-V-V-G-V-S-E-G-F-K-K-A-L-E-M-R-G-V-G-Y-R-A-Q-L-Q-G-S-K-L-V-L-S-V-G-K-S-H-Q-D-E-V-E-A-P-E-G-V-T-F-E-V-P-T-P-T-T-I-N-V-I-G-I-N-K-E-S-V-G-Q-T-A-A-Y-V-R-S-L-R-S-P-E-P-Y-K-G-K-G-I-R-Y-V-G-E-F-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-F-L-T-R-I-R-N-A-N-Q-A-K-H-E-V-L-E-V-P-A-S-N-I-K-K-G-I-A-D-I-L-K-R-E-G-F-V-K-N-V-E-V-I-E-D-D-K-Q-G-I-I-R-V-F-L-K-Y-G-Q-N-G-E-R-V-I-T-N-L-K-R-I-S-K-P-G-L-R-V-Y-T-K-H-E-D-M-P-K-V-L-N-G-L-G-I-A-I-V-S-T-S-E-G-L-L-T-D-K-E-A-R-Q-K-N-V-G-G-E-V-L-A-Y-I-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-N-K-R-P-A-K-F-S-T-Q-A-Y-T-R-C-E-K-C-G-R-P-H-S-V-Y-R-K-F-Q-L-C-R-V-C-F-R-D-L-A-Y-K-G-Q-V-P-G-V-T-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-N-R-L-K-E-K-Y-T-N-E-V-V-P-A-L-T-E-K-F-N-Y-S-S-V-M-A-V-P-K-V-E-K-I-V-L-N-M-G-V-G-D-A-V-S-N-A-K-N-L-E-K-A-A-A-E-L-A-L-I-S-G-Q-K-P-L-I-T-K-A-K-K-S-I-A-G-F-R-L-R-E-G-V-A-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-V-S-V-S-L-P-R-V-R-D-F-H-G-V-P-T-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-N-F-D-D-V-D-K-V-R-G-L-D-I-V-I-V-T-T-A-N-T-D-E-E-S-R-E-L-L-K-G-L-G-M-P-F-A-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-F-V-K-K-G-D-K-V-R-V-I-A-G-K-D-K-G-T-E-A-V-V-L-K-A-L-P-K-V-N-K-V-V-V-E-G-V-A-L-I-K-K-H-Q-K-P-N-N-E-N-P-Q-G-A-I-V-E-K-E-A-P-I-H-V-S-N-V-Q-V-L-D-K-N-G-V-A-G-R-V-G-Y-K-V-V-D-G-K-K-V-R-Y-N-K-K-S-G-E-V-L-D"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-K-V-A-D-N-S-G-A-R-E-I-L-T-I-K-V-L-G-G-S-G-R-K-F-A-N-I-G-D-V-I-V-A-S-V-K-Q-A-T-P-G-G-A-V-K-K-G-D-V-V-K-A-V-I-V-R-T-K-T-G-A-R-R-P-D-G-S-Y-I-K-F-D-D-N-A-A-V-I-I-R-D-D-K-T-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-G-Y-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-N-Q-R-K-T-L-Y-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-K-R-N-H-P-V-Y-G-K-R-I-N-Y-S-K-K-Y-K-A-H-D-E-N-N-V-A-K-E-G-D-I-V-R-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-V-V-E-K-A-V-I-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-H-R-R-E-F-R-G-K-M-R-G-E-A-K-G-G-K-E-V-S-F-G-E-Y-G-L-Q-A-T-T-S-H-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-A-K-A-I-G-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-P-V-K-R-G-K-V-M-F-E-I-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-C-K-F-V-K-R-E-A-E"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-E-I-T-S-A-K-A-M-A-R-T-V-R-V-S-P-R-K-T-R-L-V-L-D-L-I-R-G-K-N-V-A-D-A-I-A-I-L-K-F-T-P-N-K-A-A-R-V-I-E-K-T-L-N-S-A-I-A-N-A-E-N-N-F-G-L-E-K-A-N-L-V-V-S-E-T-F-A-N-E-G-P-T-M-K-R-F-R-P-R-A-K-G-S-A-S-P-I-N-K-R-T-T-H-V-T-V-V-V-S-E-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-K-M-I-V-G-L-G-N-P-G-S-K-Y-N-D-T-K-H-N-I-G-F-M-A-V-D-R-I-V-K-D-L-D-V-N-F-T-E-D-K-N-F-K-A-E-I-G-S-D-F-I-N-G-E-K-I-Y-F-I-K-P-T-T-F-M-N-N-S-G-I-A-V-K-A-L-L-T-Y-Y-N-I-S-I-K-D-M-I-I-I-Y-D-D-L-D-M-E-V-G-K-I-R-F-R-Q-K-G-S-A-G-G-H-N-G-I-K-S-I-I-A-H-L-G-T-Q-E-F-D-R-I-K-V-G-I-G-R-P-N-G-R-M-T-V-I-N-H-V-L-G-K-F-D-K-N-D-E-I-M-I-L-N-T-L-D-K-V-D-N-A-V-N-Y-Y-L-Q-T-N-D-F-Q-K-T-M-Q-K-Y-N-G-L-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-F-N-A-T-L-I-G-Q-T-V-A-F-I-I-F-V-W-F-C-M-K-F-V-W-P-P-L-M-N-A-I-E-A-R-Q-K-R-I-A-D-G-L-A-D-A-D-R-A-V-K-D-L-E-L-A-Q-A-K-A-T-D-Q-L-K-E-A-K-V-T-A-N-E-I-I-E-Q-A-N-K-R-K-A-Q-I-V-E-E-A-K-T-E-A-D-A-E-R-A-K-I-I-A-Q-G-K-A-E-I-E-A-E-R-N-R-V-K-E-D-L-R-K-Q-V-A-T-L-A-I-M-G-A-E-K-I-L-E-R-S-I-D-P-A-A-H-S-D-I-V-N-K-L-V-A-E-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-L-T-T-I-A-R-P-Y-A-K-A-A-F-D-I-A-V-E-H-N-A-V-D-N-W-A-E-M-L-T-F-A-A-L-V-S-E-N-E-T-M-K-P-L-L-T-G-S-L-A-S-T-K-L-A-A-L-F-I-S-V-C-G-E-Q-I-N-E-Q-G-Q-N-L-I-K-V-M-A-E-N-G-R-L-K-V-L-P-A-V-S-E-L-F-A-Q-Y-R-N-E-W-A-K-E-V-E-A-D-V-V-S-A-A-E-L-S-S-E-Q-Q-Q-Q-I-S-I-S-L-E-K-R-L-A-R-K-V-K-L-N-C-S-T-D-A-A-L-I-A-G-V-I-I-K-A-G-D-L-V-I-D-G-S-V-R-G-K-L-S-R-L-S-E-K-L-Q-S"} +{"text": "### FUNCTION A GTPase-activating protein that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-S-R-S-K-K-T-R-K-G-G-E-N-S-P-K-Q-Q-P-R-V-K-K-Q-D-R-A-E-V-T-G-K-R-A-E-K-G-N-K-S-G-S-R-H-N-E-A-L-I-Q-A-Q-A-P-Q-K-K-A-A-Q-K-K-D-P-R-H-G-S-K-K-P-V-A-L-A-L-P-T-T-T-E-K-S-A-T-P-K-V-K-Q-P-K-L-T-D-E-Q-K-L-L-K-L-E-E-D-P-R-L-N-Q-L-L-D-M-L-E-E-G-R-N-L-S-D-A-D-Q-K-W-L-D-Q-Q-L-N-K-I-E-A-L-M-I-K-L-G-I-S-D-E-L-E-D-E-A-P-A-K-S-K-A-D-S-D-D-D-L-F-D-R-F-E-S-G-A-E-L-L-K-D-Y-Q-D-K-F"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-S-S-F-K-H-L-S-V-N-Q-L-V-Q-M-T-E-A-K-S-V-Q-I-V-D-I-R-D-G-N-S-F-N-N-G-H-I-D-G-A-F-N-L-N-N-E-N-L-A-H-F-I-G-Q-A-D-M-D-R-P-L-V-V-V-C-Y-H-G-I-S-S-Q-N-A-A-Q-Y-L-C-E-Q-G-F-D-D-V-Y-S-L-D-G-G-F-S-A-W-H-E-A-N-A"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-T-I-S-D-A-A-Q-A-H-F-V-K-L-L-A-D-Q-P-E-G-T-H-I-R-V-F-V-I-S-P-G-T-A-Q-A-E-C-G-V-S-Y-C-P-P-D-A-V-E-S-D-D-I-E-L-A-F-N-G-F-S-A-M-V-D-E-K-S-A-P-F-L-E-E-A-S-I-D-F-V-T-D-Q-L-G-S-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-A-G-D-A-P-L-V-E-R-I-E-Y-V-I-Q-S-E-I-N-P-Q-L-A-S-H-G-G-N-I-M-L-V-E-I-T-G-E-G-V-A-V-L-Q-F-G-G-G-C-N-G-C-S-Q-V-D-I-T-L-K-D-G-I-E-K-Q-L-L-D-M-F-P-G-E-L-T-G-V-R-D-V-T-D-H-Q-H-G-E-H-S-Y-A"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-A-M-T-D-T-E-F-H-Q-L-A-D-D-M-F-Q-A-I-E-T-A-I-E-T-A-I-D-E-Q-D-A-D-V-D-I-D-A-S-G-N-V-L-Q-L-E-F-V-D-G-S-K-I-V-I-N-K-Q-E-P-L-H-E-I-W-V-A-T-R-F-G-G-Y-H-F-G-Y-V-E-G-K-W-L-D-G-R-N-G-G-E-F-M-P-F-V-Q-D-S-I-L-R-Q-S-G-I-E-L-S-L"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-T-P-I-E-L-K-I-L-D-S-R-I-G-S-E-F-P-L-P-A-Y-A-T-P-G-S-A-G-M-D-L-R-A-M-I-D-T-T-M-T-I-A-P-G-E-T-Q-L-V-P-T-G-I-A-I-H-V-A-D-P-G-L-A-A-L-I-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-V-D-S-D-Y-Q-G-P-L-M-V-S-C-W-N-R-S-D-T-P-F-T-L-E-I-G-D-R-L-A-Q-L-V-F-V-P-V-V-Q-A-Q-F-K-L-V-D-E-F-D-S-S-D-R-G-E-G-G-F-G-H-S-G-T-K"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-S-K-P-S-L-T-L-P-R-I-V-L-H-D-L-W-Q-H-K-W-I-L-L-L-A-L-L-V-L-S-N-A-V-A-V-V-Y-T-S-H-V-S-R-K-L-T-T-E-W-D-Q-L-L-Q-E-R-D-R-L-D-I-E-W-R-N-L-L-L-E-E-Q-S-Q-T-E-H-S-R-I-T-R-I-A-S-K-D-L-N-M-S-R-P-L-P-S-E-E-I-V-V-K-V-P"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-G-I-G-F-M-E-L-L-L-I-G-V-L-G-L-I-V-L-G-P-E-R-L-P-V-A-V-R-S-V-T-S-W-V-R-A-M-K-R-M-A-N-S-V-K-E-E-L-E-Q-E-L-K-I-E-Q-L-H-A-D-L-K-K-A-E-S-K-G-L-S-N-L-S-P-E-L-Q-E-S-I-E-Q-L-K-Q-A-A-Q-S-V-N-R-P-Y-Q-V-Q-D-T-P-S-A-Q-D-N-Q-I-H-N-P-A-S-Q-T-V-S-T-E-A-S-S-T-S-A-S-S-A-P-K-S-E-S-I-Q-G-E-D-P-R-S-N-T-K-A-N-G"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-I-S-I-W-Q-L-L-I-I-A-L-I-V-V-L-L-F-G-T-K-K-L-R-S-L-G-G-D-L-G-G-A-V-K-G-F-K-N-A-M-S-S-E-E-D-K-K-A-L-E-D-A-E-A-A-K-P-V-Q-T-A-Q-T-V-Q-S-A-Q-P-T-Q-Q-A-T-E-K-K-P-E-S-N-K-E-Q-A"} +{"text": "### FUNCTION Globally modulates RNA abundance by binding to RNase E and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome Modulates RNA-binding and helicase activities of the degradosome ### SEQUENCE -M-E-Y-N-T-S-E-L-C-D-M-Y-L-D-V-V-D-V-V-E-P-M-F-S-N-Y-G-G-C-S-S-F-G-G-S-I-S-T-I-K-C-F-E-D-N-G-L-I-T-D-V-L-Q-E-D-G-Q-G-K-V-L-L-V-D-G-G-G-S-L-R-R-A-L-I-D-G-T-I-A-E-L-A-V-S-N-N-W-E-G-I-I-V-Y-G-S-V-R-D-V-D-A-L-E-E-L-D-I-G-I-Q-A-L-A-S-I-P-V-G-A-D-G-N-S-V-G-E-V-D-I-P-V-N-F-G-G-V-T-F-L-P-G-D-H-I-Y-A-D-N-T-G-I-I-L-S-P-E-P-L-D-I-E"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-P-G-I-H-P-E-Y-A-E-I-T-A-N-C-T-C-G-N-V-I-K-V-N-S-T-V-G-K-D-L-H-L-D-V-C-G-A-C-H-P-F-Y-T-G-T-Q-K-V-V-D-T-G-G-R-I-D-K-F-N-K-R-F-G-M-L-G-K-K"} +{"text": "### FUNCTION This regulatory protein, when combined with SAM represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-T-E-W-N-G-E-Y-I-S-P-Y-A-E-H-G-K-K-N-E-Q-V-K-K-I-T-V-S-I-P-L-K-V-L-K-V-L-T-D-E-R-T-R-R-Q-V-N-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-Y-T-G-Q-P-L-P-D-D-A-D-L-S-K-E-C-P-D-S-I-P-A-E-A-K-R-L-M-D-E-M-G-I-E-W-E-D-M-E"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-T-A-T-P-E-T-V-T-R-D-W-F-V-V-D-A-D-G-K-T-L-G-R-I-A-T-E-I-A-L-R-L-R-G-K-H-K-P-E-Y-T-P-H-V-D-T-G-D-Y-I-I-V-I-N-A-E-K-V-T-V-T-G-N-K-A-Q-G-K-T-Y-Y-S-H-S-G-F-P-G-G-I-K-Q-I-S-F-E-K-L-Q-A-H-K-P-E-M-I-I-E-K-A-V-K-G-M-L-P-K-G-P-L-G-R-A-M-F-R-K-L-K-V-Y-A-G-A-E-H-N-H-A-A-Q-Q-P-Q-V-L-D-I"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-P-G-M-I-E-R-Y-T-G-A-I-T-E-A-N-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-Q-D-L-H-K-A-H-Y-V-L-M-N-V-E-A-P-A-E-T-I-E-E-L-E-T-A-F-R-F-N-D-A-V-L-R-N-M-V-M-R-T-K-G-A-I-T-E-A-S-P-M-A-K-A-K-D-E-R-D-S-R-R-G-P-A-G-D-R-S-Y-D-E-A-N-A-E-E-I-A-E"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-T-T-N-N-L-V-L-S-G-T-I-T-R-S-R-R-F-K-S-P-A-G-I-A-H-S-V-I-M-L-E-H-K-S-Q-R-Y-E-A-D-M-L-R-N-V-Y-V-Q-I-Q-V-I-L-S-G-P-R-F-E-S-V-A-D-N-L-K-A-G-V-E-V-Q-V-Q-G-F-M-T-L-Q-Q-G-R-N-G-Q-N-R-L-V-I-H-A-E-N-V-E-L-K-T"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-Y-F-R-R-R-K-F-C-R-F-T-A-E-G-V-A-E-I-D-Y-K-D-I-V-T-L-K-N-Y-I-T-E-S-G-K-I-V-P-S-R-I-T-G-T-S-A-K-Y-Q-R-Q-L-A-R-A-I-K-R-A-R-Y-L-S-L-L-P-Y-T-D-L-H-Q"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-N-V-I-L-L-D-K-I-A-N-L-G-N-L-G-D-Q-V-A-V-K-A-G-Y-A-R-N-Y-L-L-P-Q-G-K-A-V-V-A-N-E-S-N-V-K-V-F-E-A-R-R-A-E-L-E-A-K-L-A-A-D-L-A-A-A-N-Q-R-A-E-K-I-A-A-L-E-A-V-V-I-A-S-K-A-G-D-E-G-K-L-F-G-S-V-G-N-R-D-I-A-D-A-V-T-A-A-G-V-E-L-A-K-S-E-V-R-L-P-L-G-A-L-R-T-T-G-D-F-E-V-E-V-Q-L-H-T-E-V-K-A-V-V-K-V-S-I-V-A-E-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-A-P-G-H-T-V-R-L-E-K-L-E-V-A-T-G-S-T-V-E-F-D-Q-V-L-L-I-A-D-G-E-K-V-H-V-G-A-P-L-V-A-G-G-K-V-V-A-E-V-V-S-H-G-R-G-E-K-V-T-I-V-K-F-R-R-R-K-H-H-D-K-K-L-G-H-R-Q-W-F-T-E-V-K-I-T-A-I-N-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-S-K-S-A-K-K-R-A-L-Q-S-E-K-R-R-Q-H-N-A-S-R-R-S-M-L-R-T-Y-V-K-K-V-I-A-A-I-R-A-G-D-H-K-T-A-T-E-A-F-A-A-A-Q-P-I-V-D-R-M-A-T-K-G-L-I-H-K-N-K-A-A-R-H-K-A-R-L-N-A-K-I-K-A-L-V-A"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-S-A-T-D-T-K-V-I-D-S-R-L-V-A-E-G-H-Q-V-R-R-R-R-E-C-T-E-C-H-E-R-F-T-T-F-E-G-A-E-L-V-M-P-R-V-I-K-R-D-G-T-R-Q-P-F-D-E-E-K-L-Q-A-G-M-L-R-A-V-E-K-R-P-V-S-M-D-E-I-E-Q-A-L-S-K-I-K-S-T-L-R-A-T-G-E-R-E-V-P-S-E-M-I-G-N-L-M-M-E-Q-L-M-S-L-D-K-V-A-Y-I-R-F-A-S-V-Y-R-A-F-E-D-V-S-E-F-G-E-A-I-A-K-L-Q-K"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-P-S-E-R-R-K-A-R-R-L-A-V-Q-A-I-Y-S-W-Q-L-S-G-N-N-I-A-D-V-E-H-E-F-L-T-E-Q-S-L-D-G-V-D-V-A-Y-F-R-E-L-F-A-G-V-A-T-K-K-T-Q-L-D-E-L-I-I-P-H-L-D-R-P-I-D-E-V-S-P-V-E-K-A-I-V-R-L-A-A-Y-E-L-T-F-R-K-D-V-P-F-K-V-A-I-N-E-A-I-E-L-A-K-A-F-G-A-D-E-S-H-K-F-V-N-G-L-L-D-K-L-V-A-R-K"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-K-F-F-V-I-T-L-I-V-L-L-G-L-L-Q-Y-R-L-W-S-G-D-N-S-L-P-E-Y-F-V-L-Q-K-Q-I-A-A-Q-Q-D-G-N-A-K-L-N-E-R-N-Q-V-L-K-E-E-I-I-D-L-K-S-G-T-E-A-I-E-E-R-A-R-N-E-L-G-M-V-K-E-G-E-T-F-Y-R-V-V-G-G-D-R-A-V-S-S-P-S-Q"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-M-I-G-D-E-V-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-V-N-A-P-K-E-V-S-V-H-R-E-E-I-Y-Q-R-I-Q-S-E-K-S-G-T-P-S-E-G-G-N-F"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-H-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-A-Q-M-T-S-F-L-F-E-G-K-D-V-E-I-E-G-F-V-P-E-K-D-Q-D"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-N-A-K-T-V-L-G-F-D-F-G-T-K-S-I-G-V-A-V-G-Q-Q-I-T-A-S-A-T-P-L-L-S-I-K-A-V-D-G-I-P-N-W-E-E-I-A-K-L-I-Q-E-W-Q-P-D-L-V-V-V-G-L-P-L-N-M-D-G-T-E-Q-E-M-T-H-R-A-R-K-F-A-N-R-L-N-A-K-F-G-V-K-I-F-T-Q-D-E-R-L-T-T-T-D-A-K-A-R-L-F-E-L-G-G-Y-K-A-L-T-K-G-Q-V-D-A-V-S-A-V-L-I-I-E-S-Y-F-E-N-H-F-G-D"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-M-T-P-Q-L-I-L-A-S-T-S-V-Y-R-Q-A-L-L-R-K-L-G-L-P-F-E-Y-C-D-P-N-I-D-E-T-P-I-A-N-E-S-A-Q-A-L-V-L-R-L-A-Q-A-K-A-E-A-G-A-K-Y-F-P-D-G-L-I-I-G-S-D-Q-V-A-V-I-D-S-K-I-I-G-K-P-L-N-R-D-N-A-I-Q-Q-L-S-Q-A-S-G-K-T-I-T-F-Y-T-G-L-A-L-Y-N-A-Q-T-G-E-I-N-A-Q-V-E-P-F-T-V-H-F-R-H-L-A-A-S-Q-I-S-A-Y-V-D-K-E-Q-P-F-Y-C-A-G-S-F-K-S-E-G-L-G-I-A-L-F-S-R-L-E-G-R-D-P-N-T-L-V-G-L-P-L-I-L-L-T-E-M-L-L-S-Q-G-I-D-V-L-A"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-N-I-E-E-R-V-K-K-I-I-V-E-Q-L-G-V-K-E-E-D-V-K-P-A-A-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-A-A-I-D-Y-V-S-K-N-Q"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-G-K-T-G-N-I-E-H-V-E-E-R-V-E-S-E-L-M-P-P-S-M-Y-K-V-I-L-N-N-D-D-Y-T-P-M-D-F-V-I-E-V-L-Q-I-F-F-R-K-N-E-Q-E-A-T-D-I-M-L-T-I-H-H-Q-G-K-G-I-C-G-I-F-P-F-G-I-A-E-T-K-V-I-Q-V-N-Q-F-A-R-Q-N-Q-H-P-L-L-C-S-L-E-K-A"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-D-N-I-E-M-Q-G-T-I-L-E-T-L-P-N-T-M-F-R-V-E-L-E-N-G-H-V-V-I-A-H-I-S-G-K-M-R-K-N-Y-I-R-I-L-T-G-D-K-V-T-V-Q-L-T-P-Y-D-L-T-K-G-R-I-V-F-R-A-R"} +{"text": "### FUNCTION Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ ### SEQUENCE -M-L-L-L-P-Q-K-D-W-H-W-K-Y-N-D-S-Y-G-V-L-S-V-S-L-G-S-E-I-E-F-L-T-A-Y-K-A-K-S-L-I-P-D-A-L-S-S-M-E-F-N-I-S-H-A-K-F-Y-M-S-L-L-D-K-L-P-K-T-L-T-L-T-D-A-A-V-V-Q-I-A-L-N-A-T-A-A-H-F-M-L-T-P-Q-M-P-K-S-W-F-F-D-T-S-E-V-C-V-Y-S-D-V-G-K-V-F-E-L-K-C-Q-K-Q-R-A-L-V-L-V-V-E-N-T-L-Q-S-A-L-V-M-L-L-S-P-E-C-V-L-S-G-A-K-T-L-G-Q-F-E-T-I-K-V-M-H-N-R-L-H-P-L-R-A-Q-R-H-V-V-A-A"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-L-D-Y-F-K-S-K-K-K-P-S-T-A-V-M-A-K-E-R-L-Q-I-I-V-A-H-Q-R-G-Q-R-D-T-P-D-Y-F-P-Q-M-K-Q-E-I-I-A-V-I-R-K-Y-V-Q-I-S-D-D-Q-V-S-V-Q-L-D-Q-N-D-D-N-L-S-V-L-E-L-N-V-T-L-P-D-R"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-S-E-Y-L-L-L-L-I-S-T-V-L-V-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-S-K-L-E-S-A-I-G-M-S-M-A-T-T-F-V-L-T-L-A-S-I-L-S-Y-L-V-N-Q-Y-L-L-L-P-F-D-L-G-Y-L-R-T-M-S-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-V-V-Q-K-T-S-A-A-L-H-R-A-L-G-I-Y-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-V-N-E-K-H-D-F-I-Q-S-A-I-Y-G-F-G-A-A-V-G-F-S-L-V-L-I-L-F-S-A-M-R-E-R-L-A-A-A-D-V-P-E-P-F-K-G-G-A-I-A-M-I-T-A-G-L-M-S-L-A-F-M-G-F-T-G-L-V-K"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-K-L-A-T-R-Q-S-Q-L-S-A-K-E-V-E-G-A-I-K-E-M-L-E-Q-M-A-T-T-L-E-S-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-A-P-R-T-G-R-N-P-K-T-G-S-S-V-E-L-E-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-E-R-V-D-A-V-N-V"} +{"text": "### FUNCTION Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins Repression is relieved when the region becomes fully methylated ### SEQUENCE -M-K-Y-I-E-V-D-E-E-L-Y-R-H-I-A-S-K-T-E-R-I-G-E-S-A-S-D-I-L-R-R-L-L-G-L-S-V-D-T-V-E-Q-A-Q-P-Q-A-I-S-Q-P-S-L-E-A-A-T-P-E-P-Q-F-V-P-Q-V-E-T-F-V-A-A-A-D-F-H-Q-L-V-D-E-H-K-L-E-Q-Q-K-G-A-V-G-R-F-L-F-L-L-E-S-L-Y-Q-L-N-K-T-Q-F-A-Q-I-L-Q-I-Q-G-R-D-R-L-Y-F-A-R-S-R-E-E-L-L-K-A-S-A-T-A-N-P-K-E-I-G-Q-T-G-F-W-V-T-T-N-N-N-T-A-K-K-R-A-I-L-A-E-A-L-V-Q-F-G-C-D-A-E-I-A-N-G-I-A-E-R-V"} +{"text": "### FUNCTION General inhibitor of family S1 serine proteases ### SEQUENCE -M-K-L-P-Q-L-C-H-L-A-A-V-P-L-A-F-T-L-L-S-F-N-A-S-A-V-S-P-P-H-P-T-G-L-D-A-P-M-I-S-V-S-S-M-N-A-N-N-Y-A-P-V-E-T-V-K-M-F-P-A-P-K-K-G-M-V-Q-H-I-L-T-L-P-K-L-E-N-E-T-D-Y-M-V-E-I-Q-I-G-Q-T-Q-L-V-D-C-N-K-H-G-L-N-G-Q-L-K-E-L-T-V-E-G-W-G-Y-N-Y-Y-Q-V-D-E-I-S-E-G-P-S-T-M-M-A-C-F-E-L-A-K-K-E-A-F-V-Q-I-P-D-E-L-T-L-R-Y-D-S-R-L-P-K-V-F-Y-L-P-E-G-A-E-L-R-F-R-T-W-K-A-D-S-T-Y-Q-Y-S-K"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-N-L-L-L-V-A-L-G-G-S-I-G-A-V-F-R-Y-L-I-S-I-F-M-I-Q-V-F-G-S-S-F-P-F-G-T-L-L-V-N-V-L-G-S-F-L-M-G-V-I-Y-A-L-G-Q-M-S-H-I-S-P-E-F-K-A-L-I-G-V-G-L-L-G-A-L-T-T-F-S-T-F-S-N-E-T-L-L-L-M-Q-E-G-D-W-L-K-A-A-L-N-V-V-L-N-L-S-L-C-L-F-M-V-Y-L-G-Q-Q-L-V-F-S-R-I"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-R-A-R-H-K-K-V-L-K-L-A-K-G-Y-Y-G-A-R-S-R-T-Y-R-V-A-V-Q-A-V-T-K-A-G-Q-Y-A-Y-R-D-R-R-Q-K-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-A-R-Q-N-G-L-S-Y-S-R-F-I-N-G-L-K-K-A-S-I-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-V-V-F-A-T-L-V-E-K-A-K-E-A-L-N"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-I-K-K-T-A-G-R-Q-L-A-P-N-R-I-N-E-E-I-T-G-V-P-E-V-R-L-T-G-I-D-G-E-A-I-G-V-V-S-I-R-D-A-Q-N-L-A-D-E-A-G-V-D-L-V-E-I-S-P-N-A-E-P-P-V-C-R-I-M-D-Y-G-K-F-L-F-D-K-A-K-S-A-K-E-Q-K-K-K-Q-K-Q-V-Q-V-K-E-I-K-F-R-P-G-T-D-E-N-D-Y-Q-V-K-L-R-N-L-I-R-F-L-E-D-G-D-K-A-K-I-T-L-R-F-R-G-R-E-M-A-H-Q-N-L-G-M-D-L-L-N-R-I-K-T-D-L-D-E-Y-A-V-V-E-S-F-P-K-M-E-G-R-Q-A-I-M-V-L-A-P-K-K-K"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-Y-F-E-L-F-K-F-P-P-T-F-D-I-D-T-A-V-L-A-D-R-Y-R-E-L-Q-R-A-V-H-P-D-K-F-A-N-D-T-E-Q-Q-R-L-L-S-V-Q-R-T-A-Q-V-N-D-G-Y-Q-T-L-K-D-P-I-R-R-A-E-H-M-L-S-L-R-G-I-D-L-S-H-E-T-T-T-V-K-D-T-A-F-L-M-Q-Q-M-E-W-R-E-A-L-E-D-I-R-E-S-I-D-H-Q-A-I-I-N-E-L-Y-D-S-F-A-A-Y-R-L-K-L-T-K-L-L-A-A-Q-L-S-S-G-S-D-E-D-A-L-L-A-A-D-Q-V-R-K-L-K-F-M-A-K-L-Q-D-E-L-T-R-I-E-D-A-L-L-D"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-S-Y-T-I-T-A-Q-T-R-T-E-I-G-K-G-S-S-R-R-L-R-H-A-G-K-V-P-A-V-I-Y-G-A-G-K-E-P-V-S-I-V-F-D-H-K-D-I-I-N-A-Q-A-N-D-D-F-Y-T-S-V-V-T-I-V-L-D-G-K-E-V-G-V-R-A-Q-A-M-Q-R-H-A-F-K-P-I-I-E-H-V-D-F-V-Y-A"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-Y-S-I-V-S-A-L-I-E-Q-C-E-Q-Y-A-K-A-N-Q-A-T-K-V-T-R-V-E-I-K-L-G-V-M-S-G-V-E-P-A-L-L-Q-T-A-F-E-T-F-K-L-D-G-I-C-R-E-A-K-L-C-M-T-L-Q-P-L-V-I-K-C-A-D-C-Q-Q-E-S-V-L-D-E-R-S-I-V-C-P-A-C-N-S-Y-H-T-R-V-L-D-G-E-E-M-L-L-M-Q-L-E-M-E-Q-A-E-D-A"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-E-M-A-E-H-L-F-E-T-L-G-I-N-K-R-V-A-K-E-M-V-E-S-F-F-E-E-I-R-G-A-L-E-S-G-E-Q-V-K-L-S-G-F-G-N-F-D-L-R-D-K-N-Q-R-P-G-R-N-P-K-T-G-E-D-I-P-I-S-A-R-R-V-V-T-F-R-P-G-Q-K-L-K-T-R-V-E-A-A-N-T-G-K"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-K-F-S-P-L-L-D-E-L-I-Q-S-L-R-C-L-P-G-V-G-P-K-S-A-Q-R-M-A-F-Q-L-L-E-R-D-R-K-A-G-L-K-L-A-A-A-L-S-S-A-M-S-D-I-G-H-C-Q-S-C-R-T-Y-T-E-E-T-L-C-P-I-C-A-S-H-K-R-G-S-S-S-T-I-C-V-V-E-T-P-A-D-V-L-A-I-E-A-G-G-H-F-T-G-R-Y-F-V-L-L-G-H-L-S-P-L-D-G-V-G-P-E-E-L-G-L-A-L-L-E-R-H-L-A-S-G-D-V-A-E-L-I-L-A-T-N-P-T-V-E-G-E-A-T-A-H-F-I-A-D-M-A-R-R-H-K-V-L-I-S-R-I-A-H-G-V-P-V-G-G-E-L-E-Y-V-D-S-T-T-L-A-L-S-F-N-G-R-I-P-L"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-G-G-M-G-N-L-M-K-Q-A-Q-M-M-Q-E-R-M-A-K-M-Q-E-E-I-A-R-M-E-M-V-G-E-S-G-A-G-L-V-K-V-T-M-T-G-A-H-T-V-R-K-V-E-I-Y-P-S-L-M-E-D-D-K-E-M-L-E-D-L-I-A-A-A-C-N-D-A-A-R-I-I-E-E-N-Q-K-A-K-M-A-E-V-T-G-G-M-Q-L-P-P-G-M-K-M-P-F"} +{"text": "### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-L-T-E-I-T-F-F-E-R-F-E-H-D-I-L-M-G-K-K-T-I-T-L-R-N-E-A-E-S-H-V-I-P-G-Q-I-L-P-V-S-T-F-E-T-H-R-W-F-C-D-I-Q-V-L-E-V-T-P-I-T-L-S-G-L-T-T-L-H-A-Q-Q-E-N-M-T-L-A-E-L-R-L-V-I-A-E-I-Y-P-D-L-E-Q-L-Y-M-I-R-F-K-V-L-T-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-A-D-I-K-K-D-A-Q-E-R-M-G-K-C-V-D-A-T-K-N-Q-M-A-K-V-R-T-G-R-A-H-P-S-L-L-D-S-I-Q-V-S-Y-Y-G-T-M-T-P-L-N-Q-V-A-N-V-G-V-E-D-A-R-T-L-S-V-T-V-F-D-R-S-A-I-Q-A-V-E-K-A-I-M-S-S-D-L-G-L-N-P-M-S-A-G-A-T-L-R-I-P-L-P-A-L-T-E-E-R-R-K-D-F-I-K-V-V-R-A-E-A-E-G-G-R-V-A-I-R-N-V-R-R-D-A-I-S-D-V-K-K-L-E-K-A-K-E-C-T-E-D-D-V-R-R-F-E-D-E-V-Q-K-F-T-D-A-H-I-K-K-V-D-E-I-L-A-A-K-E-I-E-L-M-E-V"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-V-K-K-N-S-K-K-A-A-P-A-T-I-A-R-N-K-R-A-T-F-E-Y-R-F-E-E-K-M-E-A-G-L-S-L-M-G-W-E-V-K-S-I-R-M-G-K-V-N-L-S-D-C-Y-V-F-L-K-N-G-E-A-F-M-H-G-C-T-I-I-P-L-N-T-A-S-T-H-V-V-C-D-P-I-R-L-K-K-L-L-L-S-R-K-E-L-D-K-L-A-G-L-V-E-R-Q-G-Y-S-I-I-P-I-S-M-Y-W-R-K-G-A-W-V-K-V-E-I-G-L-G-K-G-K-K-D-H-D-K-R-E-D-T-K-A-R-E-W-E-V-E-K-A-R-V-M-K-K-E-K-T-R-G"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-N-I-I-K-M-L-N-D-E-Q-M-K-Q-D-V-P-A-F-G-A-G-D-T-V-V-V-Q-V-R-V-K-E-G-D-K-E-R-L-Q-A-F-E-G-V-V-I-A-K-R-N-R-G-L-H-S-A-F-T-V-R-K-I-S-N-G-E-G-V-E-R-A-F-Q-T-H-S-P-L-I-A-S-I-E-V-K-R-R-G-R-V-R-R-A-K-L-Y-Y-L-R-D-R-S-G-K-S-A-R-I-R-E-K-L-A-T-K"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-S-N-Q-Q-P-V-V-L-G-K-L-G-S-C-H-G-I-K-G-W-L-K-I-T-A-Y-T-D-S-V-E-G-I-F-D-Y-S-P-W-L-I-K-E-N-G-E-W-R-E-V-K-V-I-Q-W-R-Y-Q-G-K-A-V-V-A-E-L-E-G-V-T-T-R-E-R-A-Q-M-L-T-N-C-E-I-G-I-L-P-Q-Q-M-N-A-L-P-E-D-E-F-Y-W-R-D-L-I-G-C-E-V-I-N-T-T-G-Y-N-M-G-I-V-D-Q-I-V-E-T-G-S-N-D-V-L-L-V-K-A-N-A-K-D-S-F-G-K-V-E-R-M-V-P-F-V-P-G-Q-F-I-L-K-V-D-V-Q-G-K-Q-I-L-V-D-W-D-P-D-F"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-V-G-L-G-T-D-I-V-E-I-E-R-I-S-A-H-V-A-R-S-G-D-K-L-A-K-R-V-L-T-E-A-E-F-E-I-Y-Q-Q-H-S-Q-P-S-R-Y-L-A-K-R-F-A-A-K-E-A-A-A-K-A-L-G-T-G-I-G-R-G-V-S-F-Q-H-I-H-I-G-N-T-P-D-G-A-P-T-I-D-F-T-E-G-A-Q-Q-R-L-T-L-L-N-G-V-V-G-H-I-S-I-A-D-E-K-S-Y-A-I-A-T-V-I-L-E-S-R"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-E-L-M-N-I-A-R-V-R-W-A-C-R-R-G-M-L-E-L-D-V-L-F-Q-P-F-V-D-N-V-Y-Q-D-L-S-D-E-D-K-V-L-F-I-R-L-L-E-C-E-D-P-E-L-F-A-W-F-M-G-H-E-V-C-P-D-P-E-L-A-R-M-V-V-Q-V-R-G-R-A-A-P"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-S-D-G-F-R-A-N-V-G-I-I-I-C-N-R-Y-G-Q-V-M-W-A-R-R-F-G-Q-H-S-W-Q-F-P-Q-G-G-V-D-D-G-E-S-A-E-E-A-M-Y-R-E-L-Y-E-E-V-G-L-R-P-E-H-V-T-V-L-T-S-T-R-S-W-L-R-Y-R-L-P-K-R-L-V-R-Q-D-S-K-P-V-C-I-G-Q-K-Q-K-W-F-L-L-Q-L-K-S-Q-D-S-A-I-N-L-S-S-S-G-H-P-E-F-D-D-W-R-W-V-S-Y-W-Y-P-V-R-Q-V-V-S-F-K-R-D-V-Y-R-K-V-M-K-E-F-A-V-T-A-L-S-F-Q-T-Q-E-I-P-K-K-R-V-R-Q-K-T-T-G"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-T-D-Q-A-D-A-T-M-P-I-K-F-T-D-A-A-A-A-K-V-K-G-L-L-E-E-E-Q-N-P-A-L-K-L-R-V-Y-V-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-K-V-N-E-G-D-F-T-V-E-K-Q-G-V-Q-L-V-V-D-P-M-S-L-Q-Y-L-V-G-G-E-V-D-Y-T-S-G-L-E-G-S-R-F-F-V-K-N-P-N-A-T-T-T-C-G-C-G-A-S-F-S-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-S-T-E-A-K-A-K-I-L-A-E-F-G-R-G-A-N-D-T-G-S-T-E-V-Q-V-A-L-L-T-A-Q-I-N-H-L-Q-D-H-F-K-E-H-I-H-D-H-H-S-R-R-G-L-L-R-M-V-S-A-R-R-K-L-L-A-Y-L-K-R-T-E-A-V-R-Y-N-E-L-I-Q-K-L-G-L-R-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-E-F-S-R-T-R-R-I-G-Q-Q-L-Q-Q-E-L-A-V-V-L-Q-R-D-M-K-D-P-R-I-G-F-V-T-V-N-D-V-D-V-S-R-D-L-S-Y-A-K-V-F-V-T-F-F-E-E-D-K-D-V-V-Q-E-K-L-N-A-L-I-A-A-A-P-Y-I-R-T-L-V-A-G-R-M-K-L-R-V-M-P-E-I-R-F-V-Y-D-S-S-L-V-E-G-M-R-M-S-N-L-V-S-Q-V-I-N-S-D-K-A-K-Q-Q-Q-F-G-S-V-D-D-D-V-I-E-N-D-I-E-E-S-D-D-T-E-G-K-V"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-T-L-E-S-R-L-A-D-M-L-K-V-P-V-E-A-L-G-F-Q-L-W-G-I-E-Y-V-Q-A-G-K-H-S-I-L-R-V-F-I-D-G-E-N-G-I-N-I-E-D-C-A-N-V-S-R-Q-V-S-A-V-L-D-V-E-D-P-I-S-T-E-Y-T-L-E-V-S-S-P-G-V-D-R-P-L-F-T-A-E-Q-Y-A-A-Y-V-G-E-D-V-K-L-Q-L-T-M-P-V-A-G-S-R-N-L-K-G-A-I-T-Q-V-D-G-Q-M-L-S-V-N-V-N-G-K-E-L-V-V-A-L-D-N-I-R-K-G-N-I-I-A-K-F"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-E-I-K-L-I-V-G-L-A-N-P-G-A-E-Y-V-Q-T-R-H-N-A-G-A-W-Y-V-E-E-L-A-R-I-C-G-V-S-L-V-A-D-S-K-Y-F-G-L-T-A-R-A-V-L-H-G-K-D-V-R-L-L-I-P-T-T-Y-M-N-L-S-G-K-A-V-G-A-L-A-N-F-F-R-I-T-P-E-E-I-L-V-A-H-D-E-L-D-M-P-P-G-V-A-K-F-K-L-G-G-G-H-G-G-H-N-G-L-K-D-I-I-A-K-L-A-N-D-K-N-F-Y-R-L-R-I-G-I-G-H-P-G-D-K-N-K-V-S-G-Y-V-L-G-K-A-P-A-K-E-Q-E-L-I-N-A-A-V-D-E-A-V-R-S-T-E-I-L-F-K-E-D-M-V-K-A-M-T-R-L-H-S-F-K-A-E"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-L-D-L-A-L-D-V-Q-Y-A-T-T-S-D-Y-L-P-S-E-E-Q-L-A-L-W-V-K-T-A-I-G-N-S-M-K-Q-A-E-L-T-I-R-I-V-D-A-R-E-S-Q-M-L-N-G-T-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-A-P-P-E-I-E-L-P-L-L-G-D-L-V-I-C-A-S-V-V-E-N-E-A-R-E-Q-D-K-T-L-E-A-H-W-A-H-M-V-V-H-G-C-L-H-L-L-G-Y-D-H-I-E-D-E-E-A-E-E-M-E-S-L-E-T-Q-L-I-E-S-L-G-F-T-D-P-Y-K-E-Q"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-L-Q-L-I-A-V-G-T-R-M-P-D-W-V-T-R-G-F-E-E-Y-Q-R-R-F-P-R-D-M-A-L-E-L-I-E-I-P-A-G-K-R-G-K-N-A-D-I-V-R-I-L-Q-K-E-G-E-Q-M-L-A-A-I-P-K-G-N-H-I-V-T-L-D-L-P-G-K-N-W-T-T-P-E-L-A-S-A-M-N-K-W-Q-L-D-G-R-D-V-S-L-L-V-G-G-P-E-G-L-A-P-A-C-K-E-A-A-H-Q-S-W-C-L-S-A-L-T-L-P-H-P-L-V-R-I-V-V-A-E-S-L-Y-R-A-W-S-V-N-T-N-H-P-Y-H-R-E"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-T-V-D-H-T-R-M-N-A-P-A-V-R-V-A-K-H-M-T-T-P-K-G-D-A-I-T-V-F-D-L-R-F-C-A-P-N-K-D-I-L-S-E-R-G-I-H-T-L-E-H-L-F-A-G-F-M-R-D-H-L-N-G-D-D-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-V-P-T-E-R-Q-V-A-D-A-W-L-A-S-M-E-D-V-L-K-V-V-E-Q-S-E-I-P-E-L-N-E-Y-Q-C-G-T-Y-E-M-H-S-L-E-Q-A-Q-D-I-A-R-N-I-I-A-A-G-V-S-V-N-R-N-D-D-L-K-L-S-D-E-I-L-G-K-L"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-I-P-T-E-L-K-Y-A-S-S-H-E-W-I-R-K-E-E-D-G-S-Y-T-V-G-I-T-E-H-A-Q-E-L-L-G-D-M-V-F-V-E-L-P-E-V-G-D-T-V-T-A-G-D-D-C-A-V-A-E-S-V-K-A-A-S-D-I-Y-A-P-I-S-G-E-V-I-A-V-N-E-A-L-E-D-S-P-E-L-V-N-S-D-A-Y-G-E-G-W-F-F-R-V-M-P-S-D-E-S-E-V-D-A-L-L-D-A-E-G-Y-Q-A-V-I-D-E-E"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-Q-T-T-K-N-Q-D-D-L-V-R-I-F-K-A-I-L-K-E-E-R-F-G-S-Q-S-E-I-V-T-A-L-Q-A-E-G-F-T-N-I-N-Q-S-K-V-S-R-M-L-S-K-F-G-A-V-R-T-R-N-A-K-Q-E-M-V-Y-C-L-P-A-E-L-G-V-P-T-A-G-S-P-L-K-N-L-V-L-D-V-D-H-N-Q-A-M-I-V-V-R-T-S-P-G-A-A-Q-L-I-A-R-L-L-D-S-I-G-K-P-E-G-I-L-G-T-I-A-G-D-D-T-I-F-I-C-P-S-S-I-Q-D-I-A-D-T-L-E-T-I-K-S-L-F-N-Y-A-E"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-V-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-P-F-N-V-A-G-H-Q-N-A-Q-G-G-Y-G-A-Q-D-D-M-P-S-G-E"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-A-D-A-N-N-L-I-W-I-D-L-E-M-T-G-L-E-P-D-V-D-R-V-I-E-I-A-T-L-V-T-D-Q-E-L-N-I-I-G-Q-G-P-V-I-A-I-H-Q-S-D-E-V-L-A-A-M-D-D-W-N-Q-K-H-H-G-E-S-G-L-I-E-R-V-R-A-S-Q-V-N-E-A-E-A-V-A-Q-T-I-A-F-L-A-Q-Y-V-P-K-G-V-S-P-M-C-G-N-S-V-G-Q-D-R-R-F-L-N-R-Y-M-R-E-L-E-D-Y-F-H-Y-R-N-L-D-V-S-T-V-K-E-L-V-K-R-W-S-P-E-T-M-A-G-F-K-K-Q-N-T-H-Q-A-L-Q-D-I-Q-E-S-I-A-E-L-Q-Y-Y-R-S-K-V-F-K-I"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-L-I-Q-E-F-K-A-F-A-S-R-G-N-V-I-D-M-A-V-G-I-I-I-G-A-A-F-G-K-I-V-S-S-F-V-A-D-I-I-M-P-P-I-G-I-I-L-G-G-V-N-F-S-D-L-S-V-V-L-L-A-A-Q-G-D-A-P-A-V-V-I-A-Y-G-K-F-I-Q-T-V-I-D-F-T-I-I-A-F-A-I-F-M-G-L-K-A-I-N-S-L-K-R-K-Q-E-E-A-P-P-A-S-P-A-P-T-K-D-Q-E-L-L-S-E-I-R-D-L-L-K-A-Q-Q-E-K"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-P-L-T-V-S-C-P-I-C-K-T-P-V-E-W-G-P-Q-S-K-F-K-P-F-C-S-E-R-C-K-M-I-D-L-G-D-W-A-S-E-K-H-A-I-P-V-K-S-E-F-D-L-D-A-L-D-E-L-G-Y-D-E-D-S-F-F-K-E"} +{"text": "### FUNCTION Activates ribosomal RNA transcription Plays a direct role in upstream activation of rRNA promoters ### SEQUENCE -M-F-D-Q-T-T-N-T-E-V-H-Q-L-T-V-G-K-I-E-T-A-N-G-T-I-K-P-Q-L-L-R-D-A-V-K-R-A-V-T-N-F-F-A-Q-L-D-G-Q-E-A-Q-E-V-Y-E-M-V-L-S-E-V-E-A-P-L-L-D-I-I-M-Q-H-T-R-G-N-Q-T-R-A-A-N-M-L-G-I-N-R-G-T-L-R-K-K-L-K-K-Y-G-M-N"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-A-V-E-Q-I-G-N-R-F-D-M-I-L-V-A-A-R-R-A-R-Q-I-A-V-Q-G-K-D-P-M-V-E-E-M-N-D-K-P-T-V-I-A-L-R-E-I-E-L-G-L-V-N-A-H-T-L-D-A-D-E-R-Q-T-V-R-E-R-E-A-A-E-I-A-A-V-A-A-I-A-E-G-R-S-L"} +{"text": "### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-L-E-L-L-S-K-L-E-T-K-I-Q-A-T-L-E-T-I-E-L-L-K-M-E-L-E-E-E-K-Q-K-T-S-T-L-S-E-Q-N-N-Q-L-I-E-Q-N-Q-Q-L-Q-Q-E-L-T-S-W-N-E-K-V-T-G-L-V-G-L-L-N-S-E-I"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-T-V-I-A-L-T-A-I-F-G-I-G-R-T-R-A-R-A-I-C-A-A-T-S-I-A-E-T-A-K-I-K-E-L-S-E-A-Q-I-D-T-L-R-E-E-V-A-K-Y-L-V-E-G-D-L-R-R-E-I-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-S-L-P-L-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-S-P-A-A-G-A-K-H-A-P-K-R-V-G-R-G-M-G-S-G-L-G-K-T-A-G-R-G-H-K-G-Q-K-S-R-S-G-G-G-V-R-P-G-F-E-G-G-Q-M-P-L-K-I-R-L-P-K-F-G-F-T-S-R-R-A-M-V-T-A-E-V-R-V-L-E-L-A-K-V-N-G-D-V-I-D-L-N-A-L-K-D-A-N-V-I-T-R-N-I-Q-F-A-K-I-V-L-S-G-T-I-E-R-P-V-T-V-K-G-L-K-V-T-K-G-A-R-A-A-I-E-A-A-G-G-K-I-E-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-T-S-R-L-R-R-A-I-R-A-R-K-K-I-Q-E-L-G-V-N-R-L-V-V-H-R-T-P-R-H-I-Y-A-Q-V-I-N-P-E-A-Q-V-V-A-A-A-S-T-V-E-K-A-V-K-E-Q-L-K-S-T-G-N-V-D-A-A-K-A-V-G-K-F-V-A-E-R-A-I-E-K-G-V-T-N-V-A-F-D-R-S-G-F-K-Y-H-G-R-V-A-A-L-A-D-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-S-I-P-A-G-V-E-V-T-L-N-E-Q-T-L-T-V-K-G-A-K-G-S-L-T-R-V-I-N-N-A-V-N-V-V-I-E-N-G-V-I-K-F-L-P-V-E-G-A-V-G-A-W-A-Q-A-G-T-T-R-A-L-V-N-N-M-V-V-G-V-S-Q-G-F-E-R-K-L-K-L-V-G-V-G-Y-R-A-K-L-V-G-A-D-I-D-L-T-L-G-F-S-H-P-L-V-H-K-L-P-A-G-V-T-A-E-C-P-S-Q-T-D-I-V-L-R-G-V-D-K-Q-L-I-G-Q-V-A-A-E-I-R-G-Y-R-P-P-E-P-Y-K-G-K-G-V-R-Y-D-D-E-E-V-R-R-K-E-A-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-A-D-M-L-T-R-I-R-N-G-Q-A-A-N-K-V-S-V-K-M-P-S-A-K-L-K-V-A-I-A-K-L-L-K-E-E-G-Y-I-A-D-Y-A-V-A-D-E-A-K-P-E-L-E-I-T-L-K-Y-F-Q-G-Q-P-V-V-E-T-I-Q-R-V-S-R-P-G-L-R-I-Y-K-G-K-N-E-L-P-K-V-M-G-G-L-G-V-A-I-V-S-T-S-K-G-L-M-T-D-R-A-A-R-L-A-G-M-G-G-E-V-I-C-Y-V-A"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-S-M-K-A-R-E-A-K-R-A-Q-L-V-A-K-F-A-E-K-R-A-A-L-K-V-I-I-A-S-P-A-S-S-D-E-D-R-W-D-A-V-L-K-L-Q-A-L-P-R-D-S-S-A-S-R-Q-R-N-R-C-N-Q-T-G-R-P-H-G-F-L-R-K-F-G-L-S-R-I-K-L-R-E-A-T-M-R-G-E-V-P-G-L-R-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-K-Y-Q-E-T-V-V-A-E-L-T-Q-K-F-G-Y-T-S-V-M-Q-V-P-R-I-E-K-I-T-L-N-M-G-V-G-E-A-V-A-D-K-K-V-M-E-H-A-V-R-D-M-T-A-I-A-G-Q-K-P-V-V-T-V-A-R-K-S-V-A-G-F-K-I-R-E-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-E-F-L-E-R-L-V-D-I-A-I-P-R-I-R-D-F-R-G-L-S-A-K-A-F-D-G-R-G-N-Y-A-M-G-V-R-E-Q-I-I-F-P-E-I-D-Y-D-K-I-D-K-I-R-G-M-D-I-V-I-T-T-S-A-K-T-D-E-E-G-R-A-L-L-D-A-F-N-F-P-F-K-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-Q-D-E-V-I-V-L-A-G-K-D-K-G-K-R-A-K-V-A-Q-V-L-P-T-G-K-L-I-V-E-G-I-N-L-V-K-K-H-Q-K-P-N-P-Q-L-G-V-A-G-G-I-V-E-K-E-A-P-I-Q-A-S-N-V-A-I-F-N-P-V-T-G-K-A-D-R-V-G-F-R-F-E-D-G-K-K-V-R-F-F-K-S-N-S-E-L-V-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-T-L-D-V-A-C-N-S-G-A-R-R-V-Q-C-I-K-V-L-G-G-S-H-R-R-Y-A-G-I-G-D-I-I-K-V-S-V-K-E-A-I-P-R-A-K-A-K-K-G-D-V-Y-N-A-V-V-V-R-T-K-K-G-V-R-R-P-D-G-S-V-I-R-F-D-R-N-A-A-V-L-L-N-N-N-L-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-N-E-Q-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-D-K-I-R-T-L-Q-G-R-V-T-S-N-K-M-D-K-T-I-T-V-A-I-E-R-Q-V-K-H-P-I-Y-G-K-Y-I-K-R-T-T-K-I-H-A-H-D-E-A-N-Q-C-N-E-G-D-V-V-A-I-R-E-C-R-P-L-S-K-T-K-S-W-T-L-V-E-V-V-S-K-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-M-K-F-R-K-M-F-K-G-R-N-R-G-L-A-N-G-T-E-V-S-F-G-T-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-S-A-R-R-A-M-T-R-H-I-K-R-Q-G-Q-I-W-I-R-V-F-P-D-K-P-I-T-S-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-C-Q-I-Q-P-G-K-V-L-Y-E-M-N-G-V-S-E-V-I-A-R-E-A-F-A-L-A-A-A-K-L-P-I-K-T-T-F-V-T-K-T-V-M"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-V-L-A-K-H-R-F-A-R-T-S-A-Q-K-A-R-L-V-A-D-Q-I-R-G-L-P-V-A-K-A-L-E-I-L-T-F-S-P-K-K-A-A-V-L-V-K-K-V-L-D-S-A-I-A-N-A-E-H-N-E-G-A-D-I-D-E-L-K-V-G-A-V-F-V-D-E-G-P-T-M-K-R-I-M-P-R-A-K-G-R-A-D-R-I-M-K-R-T-S-H-I-T-V-V-V-S-D-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-V-E-K-A-M-E-A-G-D-K-K-P-I-K-T-W-S-R-R-S-M-I-I-P-N-M-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-F-V-T-D-E-M-I-G-H-K-L-G-E-F-S-P-T-R-T-Y-R-G-H-A-A-D-K-K-A-K-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-R-E-E-R-L-L-K-V-I-L-A-P-H-I-S-E-K-S-T-V-N-A-E-K-H-N-T-V-V-F-R-V-A-I-D-A-T-K-A-E-I-K-A-A-V-A-K-L-F-E-V-E-V-E-S-V-R-T-L-V-S-K-G-K-T-K-R-T-G-G-R-T-G-R-R-S-D-W-K-K-A-Y-V-T-L-A-A-G-A-D-I-D-F-V-G-G-A-E"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-R-I-R-I-R-L-K-G-F-D-H-R-L-I-D-Q-S-T-A-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-R-Y-T-V-L-I-S-P-H-V-N-K-D-A-R-D-Q-Y-E-L-R-T-H-K-R-L-V-D-I-V-E-P-T-E-K-T-V-D-A-L-M-R-L-D-L-A-A-G-V-D-V-Q-I-S-L-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-V-G-Q-R-K-I-L-P-D-P-K-F-H-S-E-L-L-A-K-F-I-N-V-I-M-Q-D-G-K-K-S-T-A-E-K-I-I-Y-K-A-L-D-V-I-A-E-K-K-G-A-N-H-L-D-I-L-E-A-A-L-D-N-V-R-P-S-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-C-E-V-R-P-V-R-R-N-A-L-A-M-R-W-L-V-E-A-A-R-K-R-G-E-K-S-M-A-L-R-L-A-G-E-M-L-D-A-S-E-N-K-G-T-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-I-T-K-D-Q-I-L-E-A-F-A-A-M-S-V-M-E-V-V-E-L-I-E-A-M-E-E-K-F-G-V-S-A-A-A-A-V-V-S-G-G-G-E-A-A-A-A-V-E-E-Q-T-E-F-N-V-I-L-T-A-H-G-D-N-K-V-A-V-I-K-A-I-R-G-A-T-G-L-G-L-K-E-A-K-A-M-S-E-A-A-P-V-A-V-K-E-G-V-S-K-E-E-A-E-A-L-K-K-E-L-V-E-A-G-A-S-V-E-I-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-R-L-E-D-K-K-A-I-V-A-E-V-N-E-A-A-K-G-A-L-S-A-V-A-A-D-S-R-G-V-T-V-G-A-M-T-G-L-R-K-K-A-R-E-A-G-V-Y-V-R-V-V-R-N-T-L-A-R-R-A-V-E-G-T-A-F-E-C-L-A-E-T-F-T-G-P-T-L-I-A-F-S-N-E-H-P-G-A-A-A-R-L-L-K-D-F-A-K-E-Q-A-N-F-E-V-K-G-A-A-F-E-G-N-F-I-P-A-A-D-I-D-R-L-A-K-L-P-T-Y-E-E-A-L-A-Q-L-M-M-T-M-K-E-A-S-A-G-K-F-V-R-T-L-A-A-L-R-D-Q-K-Q-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-D-A-Y-I-K-L-Q-V-K-S-G-S-A-N-P-S-P-P-V-G-P-A-L-G-Q-K-G-V-N-I-M-E-F-C-K-A-F-N-A-R-T-E-K-M-E-K-G-M-P-I-P-V-V-I-T-V-Y-S-D-R-S-F-T-F-E-T-K-T-P-P-A-S-Y-L-L-K-T-A-A-G-L-K-S-G-S-P-R-P-N-T-Q-K-V-G-T-I-A-R-A-K-I-Q-E-I-A-E-M-K-A-A-D-M-T-G-A-D-V-E-A-M-T-R-S-I-E-G-T-A-R-S-M-G-L-V-V-E-G"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-N-V-T-S-L-S-F-P-Y-G-E-S-I-Q-W-F-C-A-D-N-T-K-N-L-P-A-S-P-L-K-E-W-L-L-A-P-G-S-L-T-Q-K-L-K-G-C-C-N-E-F-E-V-R-I-L-G-E-G-Q-C-P-P-L-D-G-E-Y-P-N-Q-S-A-V-W-V-R-E-V-L-L-C-L-D-D-V-P-W-V-F-A-R-T-L-I-P-Q-S-L-L-S-T-R-Q-A-D-F-L-G-L-G-T-R-P-L-G-E-L-L-F-S-Q-D-S-F-V-P-G-R-I-E-I-A-R-F-A-T-N-S-R-L-A-H-L-A-Q-S-L-A-Q-N-V-E-H-E-L-W-G-R-R-R-Y-F-H-H-N-E-E-E-M-F-V-S-E-M-F-L-P-A-A-E-Q-A-I-A-R-L-C-P"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-A-E-V-A-N-N-E-Q-Q-A-P-Q-F-N-I-Q-R-V-Y-T-K-D-V-S-F-E-T-P-N-S-P-A-V-F-Q-K-E-W-N-P-E-V-K-L-D-L-D-T-R-S-A-K-L-A-D-D-V-Y-E-V-V-L-S-L-T-V-T-A-Q-N-G-G-E-T-A-F-L-C-E-V-Q-Q-A-G-I-F-S-I-A-G-L-T-E-P-Q-L-A-H-S-L-G-A-Y-C-P-N-I-L-F-P-Y-A-R-E-A-V-G-S-L-V-G-R-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-A-Q-Y-V-Q-Q-R-Q-A-A-A-A-E-E-A-N-A"} +{"text": "### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-N-D-V-F-S-T-A-Q-H-K-L-D-A-L-G-L-R-C-P-E-P-V-M-M-V-R-K-T-V-R-Q-M-A-Q-G-E-T-L-L-I-I-A-D-D-P-A-T-T-R-D-I-P-S-F-C-E-F-M-D-H-T-L-I-A-S-E-T-M-Q-T-P-Y-Q-Y-L-I-K-K-G-L"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-T-S-Y-T-F-T-R-E-L-R-L-L-T-P-A-Q-F-K-S-V-F-S-N-P-I-K-A-S-S-A-E-I-T-L-L-A-I-P-N-S-E-Q-H-P-R-L-G-L-T-V-A-K-R-Y-V-K-R-A-N-Q-R-N-R-I-K-R-V-I-R-D-S-F-R-L-N-Q-H-N-I-P-H-L-D-I-V-V-L-V-R-N-G-V-M-E-M-E-N-A-E-L-N-K-L-I-E-K-L-W-R-K-L-S-R-R-Y-N-G"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-Q-Y-R-I-K-Q-N-E-E-F-Q-Y-T-F-K-K-G-H-S-F-A-N-R-Q-L-V-I-Y-Y-R-E-K-E-D-Q-C-H-F-R-I-G-L-S-V-G-K-K-I-G-N-A-V-M-R-N-R-I-K-R-C-L-R-Q-S-F-H-E-L-E-P-D-I-K-P-A-Y-D-I-V-I-I-A-R-N-P-T-R-N-M-N-C-G-E-I-K-K-S-L-S-H-L-L-Y-K-E-G-L-L-K-N-T-R-N-K-T-S-L-R"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-K-Y-E-I-M-Y-I-I-R-P-D-I-E-E-E-A-Q-T-A-L-I-E-R-F-N-T-I-L-T-D-N-G-A-E-I-D-K-V-D-E-K-G-K-R-R-L-A-Y-E-I-N-D-Y-R-D-G-Y-Y-V-I-I-N-F-R-G-S-E-E-A-I-N-E-F-D-R-L-A-K-F-N-D-D-I-I-R-H-M-A-I-K-D-E-Q"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-A-R-R-G-R-A-K-R-R-K-V-C-Y-F-T-A-N-G-I-T-H-I-D-Y-K-D-V-D-L-L-R-R-F-I-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-Y-Q-R-K-L-T-I-A-I-K-R-A-R-T-M-A-L-L-P-Y-V-A-D"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-K-D-V-K-G-K-A-K-K-G-D-V-K-N-V-P-D-G-Y-A-R-N-Y-L-L-K-N-N-L-A-E-E-A-T-S-G-N-M-K-A-L-E-A-K-K-Q-K-A-D-Q-L-E-Q-K-E-K-E-D-A-I-N-L-K-D-K-L-A-E-I-A-V-E-L-E-A-K-S-G-D-N-G-R-L-F-G-S-I-T-S-K-Q-I-S-E-A-L-Q-K-Q-F-G-H-K-I-D-K-R-K-I-E-L-D-E-P-I-R-A-L-G-Y-T-T-V-P-V-K-L-H-P-E-V-S-G-S-I-K-V-H-V-A-E-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-E-R-K-R-Q-Q-M-V-E-K-Y-A-E-L-R-R-E-L-K-A-K-G-D-Y-E-A-I-R-K-L-P-R-D-S-S-P-T-R-L-T-G-R-C-E-V-T-G-R-P-R-G-Y-M-R-Q-F-K-M-S-R-I-A-F-R-E-Y-A-H-K-G-Q-I-P-G-V-K-K-S-S-W"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-N-I-T-I-V-S-V-G-K-L-K-E-K-Y-L-K-Q-G-I-D-E-Y-K-K-R-L-N-A-Y-A-K-V-S-I-I-E-V-A-D-E-K-A-P-E-T-M-S-E-A-E-M-K-E-V-K-R-K-E-G-E-R-I-L-S-S-I-A-P-D-A-F-V-I-T-L-E-I-E-G-K-M-L-G-S-E-Q-L-A-K-K-L-D-E-L-A-T-Y-G-K-S-K-V-V-F-V-I-G-G-S-L-G-I-S-Q-D-V-Q-R-R-S-D-L-A-L-S-F-S-K-M-T-F-P-H-Q-L-M-R-L-V-L-I-E-Q-V-Y-R-S-F-R-I-N-R-G-E-P-Y-H-K"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-S-L-Q-Q-L-T-H-D-E-I-D-H-L-S-M-I-E-L-G-V-K-I-L-K-E-E-N-K-A-M-N-Y-K-V-I-F-N-K-I-A-E-L-K-D-F-T-D-E-Q-K-Q-N-M-M-A-Q-F-Y-T-D-M-N-V-D-G-R-F-L-T-L-G-S-G-M-W-G-L-K-R-W-Y-P-V-E-Q-A-E-E-E-I-T-E-E-P-K-K-K-T-K-K-K-K-K-K-A-E-V-I-D-D-V-D-D-D-L-D-V-T-D-D-E-I-D-D-I-V-S-D-L-G-D-D-L-D-D-D-D-F-E-D-D-L-D-E-D-L-E-D-L-E-D-E-V-D-E-L-E-A-D-E-D-V-E-D-E-N-D-D-D-N-T-R"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-P-F-T-S-E-I-I-S-I-I-L-L-A-I-G-L-S-M-D-G-F-S-V-S-L-G-L-G-M-Q-Q-L-R-L-K-R-I-A-Y-I-G-L-T-I-G-F-L-H-M-L-M-P-L-A-G-M-L-L-G-Q-V-I-S-E-Q-I-G-Q-W-T-S-F-A-G-G-V-L-L-F-L-I-G-A-H-M-F-F-S-A-F-R-L-T-E-G-F-R-W-Q-P-V-G-V-G-L-W-I-I-A-F-S-V-S-L-D-S-F-T-V-G-L-G-L-G-I-S-G-V-Q-I-F-V-T-L-F-A-F-G-I-V-S-C-F-L-T-W-L-G-M-L-I-G-R-K-V-Y-R-F-L-G-V-Y-S-E-L-L-G-G-S-I-L-C-G-F-G-I-F-I-L-F-S"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-H-S-Y-I-D-L-L-N-I-G-A-S-V-G-G-L-R-W-P-D-M-L-V-Q-L-F-F-F-L-I-L-L-A-L-L-K-K-F-A-W-G-P-L-M-S-K-M-E-E-R-E-N-Y-V-A-N-E-I-E-S-A-E-Q-S-R-A-E-A-E-K-A-S-K-D-A-A-E-Q-L-N-Q-V-K-A-E-A-Q-K-M-I-E-D-A-K-A-A-G-A-K-Q-E-Q-A-I-I-D-S-A-R-E-E-A-D-R-I-K-E-A-A-Q-A-D-I-Q-N-E-K-E-R-A-I-Q-A-L-Q-D-K-V-A-S-L-S-V-L-I-A-S-K-V-I-E-K-E-L-S-E-Q-D-Q-E-K-L-I-N-E-Y-I-Q-E-V-G-E-D-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-N-S-V-V-A-K-R-Y-A-D-A-L-F-Q-L-G-R-E-K-N-S-L-D-Q-L-V-A-D-F-L-E-V-R-Q-I-F-T-N-D-Q-K-L-N-V-F-L-K-H-P-K-I-D-N-E-K-K-K-Q-F-L-A-D-V-F-K-G-A-D-P-V-V-I-N-T-L-K-L-L-V-D-R-H-R-T-S-T-I-P-S-I-V-D-H-L-V-A-L-V-N-D-T-K-G-I-A-D-A-T-V-Y-S-I-R-E-L-N-T-D-E-K-E-Q-L-Q-T-S-F-A-K-R-L-G-K-R-S-V-Q-I-T-N-V-V-D-P-K-I-L-G-G-M-K-I-R-V-G-N-T-I-Y-D-G-T-V-S-N-K-L-N-R-I-S-R-S-I-V-S-A-N-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-R-T-L-E-V-S-V-V-T-P-G-G-P-V-L-E-E-S-F-E-M-V-V-C-K-A-E-T-G-E-I-G-I-L-P-G-H-I-P-L-V-S-P-L-Q-I-S-A-V-R-L-K-K-G-N-D-T-K-Y-L-A-I-S-G-G-F-M-E-V-Q-P-E-K-V-T-I-L-A-Q-S-A-E-T-A-S-D-I-N-V-Q-R-A-K-E-A-K-D-R-A-E-R-R-L-Q-A-K-K-D-N-I-D-K-T-R-A-E-L-A-L-K-R-A-I-N-R-L-D-V-G-K"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-R-N-V-L-I-V-M-L-G-G-F-I-G-A-N-L-R-Y-W-L-G-E-W-M-S-S-S-S-G-F-P-T-G-T-F-V-I-N-A-I-G-C-F-L-L-G-W-L-L-T-Y-S-E-K-N-R-L-L-S-K-E-W-S-L-L-L-G-T-G-L-I-G-S-F-T-T-F-S-T-F-S-V-E-T-L-L-L-I-E-S-A-K-Y-I-V-A-S-L-Y-V-F-G-S-I-F-L-G-I-G-L-A-Y-I-G-V-R-L-A-L-Y-C-K-K-E-E-D-I-A"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-P-L-E-F-H-S-G-K-V-C-P-L-N-R-A-N-V-D-T-D-Q-I-I-P-K-Q-F-L-K-R-I-E-R-T-G-F-G-Q-F-L-F-F-H-W-R-F-N-D-D-G-T-E-R-S-D-F-V-L-N-D-P-D-Y-K-G-S-S-I-L-V-A-G-D-N-F-G-C-G-S-S-R-E-H-A-P-W-A-L-A-D-Y-G-F-K-V-I-I-A-P-D-F-A-D-I-F-Y-N-N-A-L-K-N-G-I-L-V-I-K-M-D-E-Q-Q-V-K-S-W-M-Q-K-A-V-D-G-L-T-L-D-V-D-L-K-Q-Q-T-I-Q-A-S-D-G-T-I-T-S-F-D-I-T-P-Y-Q-R-E-K-L-I-N-G-W-D-D-I-A-L-T-L-L-K-E-E-K-I-A-A-Y-E-S-A-N"} +{"text": "### FUNCTION Removes 5-oxoproline from various penultimate amino acid residues except L-proline ### SEQUENCE -M-K-K-I-L-L-T-G-F-V-P-F-L-D-N-P-I-N-P-T-E-E-I-V-Q-G-L-H-K-K-S-V-N-G-W-E-V-V-G-E-V-L-P-V-D-F-H-V-T-G-D-H-L-V-E-L-I-H-K-V-Q-P-S-A-I-I-S-L-G-L-A-A-G-R-N-R-I-T-P-E-R-I-A-I-N-C-N-D-G-P-V-D-N-Q-G-Y-K-P-D-G-E-K-I-I-S-D-G-P-D-G-Y-F-S-S-L-P-I-K-K-M-V-K-E-L-E-N-N-G-I-P-A-K-I-S-N-T-A-G-A-Y-L-C-N-H-V-M-Y-R-A-L-H-E-I-E-Q-Q-K-L-D-I-F-S-G-F-I-H-I-P-A-S-H-K-L-A-L-T-N-N-I-P-S-F-A-Q-K-D-L-Q-R-A-I-E-I-C-I-G-C-L-D"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-Q-I-E-S-S-Y-L-G-S-I-D-I-D-V-K-K-I-L-Q-F-P-A-G-L-P-G-F-A-E-E-K-E-F-V-I-L-E-I-P-E-N-P-M-F-H-V-L-Q-S-V-H-N-P-N-L-A-F-V-I-T-D-P-Y-Q-I-Y-T-S-Y-T-F-E-L-D-D-Y-T-I-E-S-L-Q-I-T-S-Q-E-D-V-A-V-F-A-I-M-T-L-K-E-P-F-H-K-S-T-I-N-L-K-A-P-I-V-I-N-M-K-K-Q-L-A-K-Q-Y-V-L-N-L-D-E-Y-S-S-Q-A-S-I-Q-S-P-P-L-K-E-G-E"} +{"text": "### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-V-L-T-R-K-Q-S-E-A-I-Q-I-G-E-D-I-E-I-E-V-I-A-I-E-G-E-Q-V-K-L-G-I-R-A-P-K-S-V-D-I-Y-R-K-E-I-Y-V-D-I-T-N-Q-N-N-E-A-A-I-I-D-K-N-L-L-Q-F-L-K-N-N-N-S"} +{"text": "### FUNCTION May act as an export chaperone for the filament capping protein FliD ### SEQUENCE -M-N-R-V-E-P-I-F-K-I-T-K-S-M-Q-H-L-L-N-V-E-I-T-N-K-N-R-E-Q-V-I-G-M-L-Q-Q-K-I-E-E-R-E-Q-I-L-Q-D-L-T-Q-P-Y-S-I-E-E-E-A-L-G-I-E-V-V-K-L-N-Q-Q-I-E-M-K-M-N-V-I-F-D-Q-I-K-V-E-L-K-L-M-K-K-K-K-K-F-N-N-S-Y-T-N-P-Y-Q-H-V-Q-S-S-D-G-Y-F-M-D-N-K-K"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ClpXP is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor ### SEQUENCE -M-N-L-V-P-T-V-I-E-Q-T-N-R-G-E-R-A-Y-D-I-Y-S-R-L-L-K-D-R-I-I-L-L-G-S-G-I-D-D-N-V-S-N-S-I-V-A-Q-L-L-F-L-E-A-E-D-P-D-K-D-I-S-L-Y-I-N-S-P-G-G-S-I-T-A-G-M-A-I-Y-D-T-M-N-F-I-K-P-N-V-S-T-I-C-I-G-M-A-A-S-M-G-A-F-L-L-T-A-G-E-K-G-K-R-F-A-L-P-N-S-E-I-M-I-H-Q-P-L-G-G-T-Q-G-Q-A-T-D-I-E-I-H-A-K-R-I-I-D-I-K-R-R-M-N-E-I-M-A-E-K-T-G-Q-P-I-E-V-I-E-R-D-T-E-R-D-N-F-M-T-A-D-Q-S-V-E-Y-G-L-I-D-K-I-L-E-R-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-P-K-G-N-G-K-V-I-A-Q-N-K-K-A-S-H-D-Y-F-I-E-D-T-Y-E-A-G-I-V-L-H-G-T-E-I-K-S-I-R-N-G-R-V-N-I-K-D-S-H-A-R-I-D-R-K-G-E-V-Q-L-I-N-L-H-I-A-E-Y-E-Q-G-N-R-Y-N-H-D-P-T-R-S-R-K-L-L-L-H-R-K-E-I-D-K-L-I-G-L-T-Q-Q-Q-G-Y-A-L-V-P-L-K-I-Y-L-K-N-G-F-A-K-V-L-I-G-L-G-K-G-K-K-K-Y-D-K-R-E-D-L-K-Q-K-Q-M-K-R-D-V-D-R-A-I-K-D-H-M-R"} +{"text": "### FUNCTION Catalyzes the reduction of arsenate ### SEQUENCE -M-S-K-K-I-I-Y-F-L-C-T-G-N-S-C-R-S-Q-M-A-E-G-W-G-K-K-I-L-G-E-E-W-D-V-Y-S-A-G-I-E-A-H-G-L-N-P-N-A-I-K-A-M-R-E-V-D-I-D-I-T-N-Q-T-S-D-Q-I-D-K-D-I-L-N-K-A-D-F-V-V-T-L-C-G-D-A-K-D-K-C-P-M-T-P-P-H-V-K-R-D-H-W-G-F-E-D-P-A-K-A-Q-G-T-E-E-E-K-W-T-V-F-Q-Q-V-R-D-K-I-G-D-R-I-K-V-F-A-K-T-G-E"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-L-P-Q-D-L-L-Y-S-K-E-H-E-W-V-K-Q-E-D-G-K-L-R-I-G-I-T-D-F-A-Q-D-E-L-G-D-I-V-F-V-E-L-P-E-I-G-E-E-L-K-V-D-D-P-F-G-S-V-E-S-V-K-T-V-S-E-L-Y-A-P-V-S-G-K-V-V-E-I-N-D-D-L-E-D-S-P-E-Y-V-N-E-S-P-Y-E-K-A-W-M-I-V-I-E-P-S-D-E-K-E-L-E-E-L-L-S-A-E-N-Y-E-A-F-I-Q-D"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-S-N-C-Q-N-K-N-T-K-V-L-D-S-R-P-I-E-E-G-R-A-I-R-R-R-R-E-C-E-R-C-G-F-R-F-T-T-F-E-R-I-E-E-V-P-L-I-V-V-K-K-D-G-V-R-Q-E-F-S-R-E-K-L-M-R-G-L-I-R-A-C-E-K-R-P-V-A-L-E-T-I-E-S-I-A-L-E-V-E-K-K-L-R-N-A-G-N-P-E-V-S-S-N-S-I-G-E-M-V-M-E-L-L-S-K-V-D-E-V-S-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-I-T-V-F-L-D-E-L-K-D-I-I-N-T-D-K-S-M-K-D-K"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-K-D-M-N-V-N-E-K-I-R-A-R-E-V-R-L-I-D-S-N-G-D-Q-L-G-V-K-S-R-Q-E-A-L-D-I-A-T-T-R-N-L-D-L-V-L-V-A-P-N-A-K-P-P-V-C-R-I-M-D-Y-G-K-Y-R-F-E-Q-Q-K-K-E-K-E-A-R-K-K-Q-K-V-I-N-V-K-E-V-R-F-T-P-G-I-G-D-H-D-F-E-T-K-L-K-N-A-R-K-F-L-E-K-G-D-K-V-K-A-A-V-R-F-R-G-R-A-I-T-H-K-E-L-G-R-E-V-L-D-R-F-A-E-E-V-K-D-L-G-T-I-E-T-K-P-K-M-E-G-R-N-M-F-M-M-V-A-P-I-N-E-K-N"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-G-G-T-V-T-R-Q-R-R-K-R-V-L-K-L-A-K-G-Y-Y-G-S-K-R-T-L-F-K-T-A-K-Q-Q-V-I-K-S-G-Q-Y-A-Y-R-D-R-R-Q-K-K-R-D-F-R-K-L-W-I-T-R-I-N-A-A-A-R-M-H-D-L-S-Y-S-K-L-M-H-G-L-K-V-A-G-I-D-I-N-R-K-M-L-S-D-L-A-I-S-D-E-K-A-F-A-Q-L-V-S-Q-A-K-E-A-L-K"} +{"text": "### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-S-Q-E-D-K-Q-R-I-T-V-E-I-Y-N-R-K-Y-H-I-V-G-E-E-S-E-R-H-M-Q-L-V-A-D-L-V-D-Q-K-M-N-E-I-H-E-V-N-K-Q-L-D-T-S-S-L-A-V-L-T-A-V-N-T-M-N-D-Y-L-K-L-K-E-D-Y-A-T-L-L-G-S-I-K-K-K-E-D"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-K-V-N-H-A-E-I-V-I-S-A-V-S-K-K-Q-Y-P-E-D-Q-L-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-R-L-I-N-R-K-N-L-A-R-T-S-S-K-P-G-K-T-Q-T-L-N-F-Y-R-I-N-E-S-F-Y-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-K-E-R-E-K-W-G-R-M-M-E-E-Y-F-Q-T-R-D-T-L-R-A-V-V-L-V-T-D-L-R-H-D-P-T-Q-D-D-I-Q-M-Y-D-F-I-K-Y-F-D-L-P-V-I-I-I-G-T-K-L-D-K-I-T-K-N-K-R-Q-K-H-I-N-R-A-K-Q-V-L-E-M-D-E-T-D-L-F-I-P-F-S-A-E-I-G-E-G-K-D-E-A-W-S-A-L-S-R-Y-I-K-R"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-E-T-G-G-K-Q-I-K-V-V-E-G-Q-E-I-Y-V-E-K-V-T-A-D-V-N-E-S-V-T-F-D-K-V-L-F-I-G-G-D-D-V-K-V-G-A-P-L-I-D-G-A-T-V-T-A-K-V-E-K-H-G-R-Q-K-K-I-D-V-H-K-F-K-P-K-K-N-Y-H-R-K-Q-G-H-R-Q-P-Y-T-K-L-V-I-D-K-I-N-A"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-E-F-K-N-Y-I-E-I-V-E-D-W-P-K-E-G-I-K-F-K-D-I-T-P-L-M-A-D-G-K-A-F-K-S-A-V-D-E-I-V-D-Y-A-N-T-K-E-I-D-L-V-V-G-P-E-A-R-G-F-I-V-G-C-P-V-S-Y-A-L-E-V-G-F-A-P-V-R-K-E-G-K-L-P-R-E-V-I-K-V-D-Y-G-L-E-Y-G-E-N-V-L-T-I-H-K-D-A-I-K-P-G-Q-R-V-L-I-T-D-D-L-L-A-T-G-G-T-I-E-A-T-I-K-L-V-E-Q-L-G-G-I-V-V-G-C-A-F-L-V-E-L-G-Y-L-D-G-K-D-K-L-E-G-Y-D-V-L-T-L-M-K-Y"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-K-I-I-G-L-D-V-G-S-K-T-I-G-V-A-V-S-D-A-L-G-W-T-A-Q-G-V-K-T-I-R-W-D-E-N-D-L-S-S-A-D-E-E-L-E-K-I-I-S-E-H-E-I-G-K-A-I-I-G-L-P-K-N-M-N-G-T-I-G-E-R-G-E-A-S-Q-R-Y-A-N-H-I-E-K-V-F-Q-I-P-V-D-L-W-D-E-R-L-T-T-M-A-A-E-R-V-L-L-E-A-D-M-S-R-S-K-R-K-K-V-I-D-K-M-A-A-V-M-I-L-Q-G-Y-L-D-Q-K"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-T-V-E-K-S-Y-Y-M-T-Q-E-G-K-D-K-L-E-E-E-L-H-Y-L-K-T-D-R-R-Q-E-V-V-E-R-I-K-V-A-R-D-F-G-D-L-S-E-N-S-E-Y-D-A-A-K-D-E-Q-A-F-V-E-Q-R-I-T-Q-V-E-K-M-I-R-N-A-V-I-I-E-N-D-N-D-N-P-N-I-V-S-L-G-K-S-V-S-F-V-E-L-P-D-G-D-E-E-T-Y-T-I-V-G-S-A-E-A-D-P-F-E-G-K-I-S-N-D-S-P-M-A-T-S-L-L-G-K-E-I-G-E-E-V-T-V-T-T-P-G-G-D-I-D-V-R-I-T-N-V-E"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-R-E-I-G-I-L-G-G-T-F-D-P-P-H-L-G-H-L-L-I-A-E-E-V-R-R-A-K-E-L-D-E-I-W-F-I-P-T-N-T-P-P-H-K-E-D-T-T-T-S-A-D-H-R-T-S-M-I-Q-L-A-I-D-S-H-P-S-F-K-L-N-D-M-E-L-K-R-E-G-K-S-Y-T-Y-D-T-I-Q-E-L-T-D-L-Y-P-S-H-T-F-Y-F-I-I-G-G-D-M-V-E-F-L-P-K-W-H-R-I-D-E-L-L-E-M-I-T-F-I-G-V-S-R-P-G-Y-S-L-Q-T-S-Y-P-V-D-F-V-D-I-P-T-I-Q-L-S-S-T-I-L-R-E-R-L-Q-N-R-E-W-I-R-Y-L-L-P-D-S-V-M-Q-Y-V-R-E-H-Q-L-Y-G-F-G-R-N"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-V-E-V-N-E-K-K-R-V-S-N-S-K-Q-L-S-A-M-R-T-E-V-K-R-V-E-K-A-V-E-A-N-D-T-D-N-A-K-S-L-F-Q-S-A-S-K-H-I-D-K-A-A-Q-K-G-I-I-H-Q-N-A-A-N-R-Q-K-S-R-L-A-N-K-I-N-A-L"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-H-I-D-F-H-D-E-T-N-S-V-S-E-D-Y-I-D-L-I-Q-R-L-L-D-F-A-A-Q-K-E-G-V-T-S-E-A-E-L-S-V-N-F-V-D-N-K-E-I-Q-V-L-N-R-N-Y-R-Q-K-D-T-P-T-D-V-I-S-F-A-M-Q-E-S-N-E-D-E-M-E-I-I-G-A-D-G-P-L-V-L-G-D-I-V-I-S-V-D-K-A-K-E-Q-S-I-E-Y-D-H-S-L-E-R-E-L-G-F-L-A-V-H-G-F-L-H-L-L-G-Y-D-H-M-K-E-E-D-E-K-K-M-F-S-R-Q-E-E-I-L-G-E-F-G-V-E-R"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-V-N-D-F-K-T-G-L-T-V-E-V-D-N-D-I-W-Q-V-I-E-F-Q-H-V-K-P-G-K-G-A-A-F-V-R-S-K-L-R-N-L-R-S-G-N-I-Q-E-K-T-F-R-A-G-E-K-V-S-K-A-H-I-E-N-R-K-M-Q-Y-L-Y-A-S-G-D-A-H-A-F-M-D-T-N-T-Y-D-Q-I-E-I-Q-G-K-Q-I-Q-E-Q-L-K-F-I-K-E-N-M-E-V-S-I-V-S-Y-E-N-E-I-L-G-V-D-L-P-N-N-V-E-L-T-V-T-E-T-E-P-G-I-K-G-D-T-A-S-G-G-S-K-P-A-T-L-E-T-G-L-I-V-Q-V-P-F-F-I-N-E-G-D-V-L-V-I-N-T-S-D-G-K-Y-V-S-R-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-N-R-H-K-A-R-E-K-A-F-Q-V-L-F-Q-L-D-I-N-E-T-E-L-E-E-V-M-E-T-L-K-E-K-E-R-Y-D-V-F-L-R-S-L-V-E-G-V-I-Q-H-K-S-V-I-D-E-K-I-S-T-H-L-E-K-W-T-I-D-R-I-A-S-V-E-R-T-I-L-R-M-A-I-L-E-I-M-Y-I-D-D-I-P-Q-N-V-S-I-N-E-A-I-E-L-A-H-T-F-G-D-E-Q-S-G-K-F-V-N-G-V-L-S-K-I-I-A"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-T-K-D-L-T-F-E-Q-A-M-E-K-L-E-G-I-V-S-K-L-E-E-G-D-V-P-L-E-K-A-I-E-Y-Y-Q-E-G-M-N-L-S-K-L-C-S-E-K-L-N-H-V-Q-D-K-M-V-Q-I-M-N-E-Q-G-E-L-E-P-F-D-I-Q-E-D-S-S-S"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-N-M-N-E-F-K-G-V-I-E-G-L-L-F-A-S-G-D-E-G-V-T-A-K-Q-L-S-K-I-L-D-I-G-L-D-T-V-E-H-I-L-E-E-L-R-F-E-Y-E-R-E-D-R-G-L-M-I-I-Q-S-N-N-I-F-H-L-A-T-K-P-E-H-S-S-Y-F-K-R-L-I-D-S-P-R-T-S-K-M-S-Q-A-A-L-E-T-L-A-I-I-A-Y-R-Q-P-I-T-R-A-E-I-D-E-I-R-G-V-R-S-E-R-P-V-Q-T-L-I-T-R-N-L-I-E-E-T-G-R-K-D-T-V-G-R-P-V-L-F-Q-T-S-K-E-F-L-T-F-F-G-L-A-T-L-D-D-L-P-P-L-P-E-N-I-D-P-D-K-E-E-R-E-A-D-L-F-F-E-R-F-Q-D-E-V"} +{"text": "### FUNCTION Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease When overexpressed, inhibits sporulation Also involved in Spx degradation by ClpC ### SEQUENCE -M-R-I-E-R-V-S-T-D-Q-F-K-I-F-L-T-F-D-D-L-I-E-R-G-F-T-R-E-D-L-W-H-D-A-S-N-V-R-S-L-F-S-D-M-M-Y-E-A-S-S-E-L-G-I-E-L-E-G-M-L-L-V-Q-V-H-L-M-Q-A-Q-G-M-H-I-F-V-T-Q-Q-Y-E-D-N-S-E-D-E-D-Y-I-E-M-K-V-T-L-D-E-S-K-E-L-I-F-S-F-M-D-F-E-D-I-I-S-V-T-S-Y-L-D-P-M-G-L-E-N-I-R-L-Y-Y-M-E-D-R-Y-Y-M-I-L-D-H-I-E-L-S-R-V-D-K-E-D-I-I-G-V-M-S-E-Y-A-N-P-S-I-V-T-S-H-R-I-E-E-Y-G-K-L-I-M-E-E-N-T-V-Q-Q-I-K-R-F-F-Y"} +{"text": "### FUNCTION Required for transcription attenuation control in the Trp operon This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination Binds the leader RNA only in presence of L-tryptophan ### SEQUENCE -M-T-D-R-T-D-K-A-E-Y-F-I-I-K-A-L-E-N-G-V-N-V-M-G-L-T-R-G-H-D-T-R-F-H-H-T-E-K-L-D-Q-G-E-V-M-I-A-Q-F-T-E-H-T-S-A-I-K-V-R-G-K-A-L-I-Q-T-S-H-G-E-I-T-N-E"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-N-I-A-L-I-A-H-D-E-K-K-E-D-M-I-Q-F-T-T-A-Y-T-H-V-L-S-K-H-R-L-F-A-T-G-T-T-G-M-K-I-S-N-A-T-G-L-Q-I-H-R-F-Q-S-G-P-L-G-G-D-Q-Q-I-G-A-M-I-A-N-G-E-M-D-M-I-I-F-F-R-D-P-L-T-A-Q-P-H-E-P-D-V-S-A-L-M-R-L-C-D-V-H-Q-I-P-L-V-T-N-I-A-G-A-E-I-F-I-H-G-L-S-R-G-D-L-K-W-R-E-I-I-K-E-R-Q-E-K-E-G-T-P"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-S-V-N-R-I-Q-L-S-G-K-D-I-L-E-K-D-F-K-T-G-I-R-G-Y-S-Q-E-E-V-D-E-F-L-D-V-I-I-Q-D-Y-D-N-F-K-Q-E-I-D-R-L-K-A-E-N-E-K-L-K-K-S-T-P-A-V-E-Q-S-R-S-R-S-Q-Q-P-P-T-S-Q-V-N-Y-D-V-L-K-R-L-S-N-L-E-K-A-V-F-G-K-R-Y-T-E-Q-E-E-S"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-Q-S-V-N-I-Q-D-Q-Y-L-N-Q-L-R-K-N-H-I-S-V-T-V-F-L-T-N-G-F-Q-L-R-G-L-V-K-A-F-D-N-F-T-V-L-L-E-T-D-G-K-Q-Q-L-I-F-K-H-A-I-S-T-F-S-P-V-K-N-V-S-L-D-K-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-T-Q-E-R-K-N-E-I-I-S-E-Y-K-V-H-E-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-E-E-I-T-S-L-N-E-H-L-R-V-H-K-K-D-H-H-S-R-R-G-L-L-K-M-V-G-K-R-R-N-L-L-T-Y-L-R-N-K-D-V-T-R-Y-R-E-L-I-K-K-L-G-L-R-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-E-L-R-A-H-R-I-A-E-Q-M-K-K-E-L-G-E-I-L-S-R-K-I-K-D-P-R-V-G-F-V-T-V-T-D-V-E-V-T-G-D-L-Q-Q-A-K-V-Y-I-S-V-L-G-D-E-K-K-K-Q-D-T-L-L-G-L-S-K-A-K-G-F-I-R-S-E-I-G-N-R-I-R-L-R-K-T-P-E-I-T-F-E-F-D-E-A-L-E-Q-G-N-R-I-E-T-I-L-R-D-L-N-K"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-S-H-V-V-S-L-T-E-E-L-V-T-P-I-L-E-E-K-N-L-E-L-V-D-I-E-Y-V-K-E-G-K-N-W-F-L-R-V-Y-I-D-K-E-G-G-I-D-I-M-E-C-G-E-V-S-E-L-L-S-E-K-L-D-E-S-D-P-I-T-E-A-Y-F-L-E-V-S-S-P-G-V-E-R-P-L-K-K-K-E-D-F-D-A-S-I-G-K-N-I-F-V-K-L-Y-E-P-I-D-G-S-K-E-Y-E-G-T-L-Q-S-F-D-G-E-T-V-T-M-E-Y-K-V-K-T-R-K-K-Q-V-E-I-P-Y-S-K-I-A-K-A-R-I-A-V-T-F"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-A-S-E-L-K-E-M-E-Q-K-M-E-Q-A-V-Q-A-L-S-K-N-L-A-S-V-R-A-G-R-A-N-P-S-I-L-D-S-V-F-V-D-Y-Y-G-A-S-T-P-L-N-Q-L-A-S-V-G-A-P-E-A-R-L-L-T-I-T-P-Y-D-K-S-A-I-G-D-I-E-K-A-I-Q-K-A-D-L-G-L-S-P-S-S-D-G-N-I-I-R-I-N-I-P-A-L-T-Q-E-R-R-K-D-L-V-K-V-V-G-K-Y-S-E-E-A-K-V-Q-I-R-N-I-R-R-D-T-N-D-Q-L-K-K-M-E-K-N-G-D-L-T-E-D-D-L-R-G-F-Q-D-D-V-Q-T-S-T-N-D-Y-I-N-K-I-D-Q-L-A-K-N-K-E-N-E-I-M-E-V"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-T-S-I-E-T-T-V-V-K-V-G-I-A-D-L-K-I-I-Q-F-P-Q-L-I-R-T-S-G-L-G-S-C-V-G-T-V-I-Y-D-D-K-K-E-I-A-G-L-S-H-V-L-L-P-Y-S-Q-Q-G-K-Q-A-N-T-N-P-Y-K-Y-A-D-T-A-I-S-Y-L-Y-N-E-L-L-K-R-G-A-N-Q-S-S-L-K-A-K-L-A-G-G-A-Q-M-F-Q-L-R-T-G-S-D-L-M-R-I-G-P-R-N-V-E-S-V-E-L-A-L-A-E-F-G-I-P-I-V-S-K-D-V-G-G-N-L-G-R-T-I-E-F-D-P-R-S-K-L-L-A-V-R-K-I-N-Q-E-V-I-M-I"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-Q-Q-I-I-A-D-I-T-K-D-Q-L-R-T-D-H-P-D-F-R-P-G-D-T-L-K-V-H-V-K-V-V-E-G-N-R-E-R-I-Q-V-F-E-G-V-V-I-K-R-Q-N-G-G-I-S-E-T-F-T-V-R-K-I-S-Y-G-V-G-V-E-R-T-L-P-L-H-S-P-R-I-D-K-I-E-V-S-R-R-G-I-V-R-R-A-K-L-Y-Y-L-R-N-L-R-G-K-A-A-R-I-K-E-R-R"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-G-V-K-F-N-I-G-K-I-V-N-T-H-G-I-R-G-E-V-K-V-V-R-I-T-D-F-E-D-R-F-D-P-G-N-T-V-Y-L-Q-D-N-K-E-Y-K-P-L-V-I-A-T-H-R-V-H-K-G-F-D-L-L-Q-F-K-G-Y-G-N-I-N-E-V-E-A-F-K-G-L-M-L-S-I-D-E-D-Q-L-T-D-L-E-E-D-A-Y-Y-Y-H-E-I-V-G-C-K-V-V-T-S-E-G-E-E-L-G-K-V-K-E-I-L-S-P-G-A-N-D-V-W-V-V-Q-R-M-N-A-K-D-L-L-I-P-Y-I-E-Q-V-V-K-Q-V-D-I-E-N-K-I-I-K-V-Q-L-M-E-G-M-L-D"} +{"text": "### FUNCTION A probable RNA chaperone Forms a complex with KhpB which binds to cellular RNA and controls its expression Plays a role in peptidoglycan homeostasis and cell length regulation ### SEQUENCE -M-K-A-L-I-E-S-I-V-A-S-L-V-D-Y-P-E-E-I-V-I-N-K-T-E-E-E-S-K-V-V-Y-H-L-T-V-H-P-D-D-V-G-K-V-I-G-K-N-G-R-I-A-K-A-I-R-T-V-V-Y-A-S-K-T-D-G-N-K-R-I-Y-L-D-I-M"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-E-V-F-D-R-V-K-E-I-I-I-D-R-L-D-V-E-E-S-K-V-T-M-E-A-S-F-K-D-D-L-D-A-D-S-L-D-V-V-E-L-V-M-E-L-E-D-E-F-D-M-E-I-A-D-E-D-A-E-K-I-N-T-V-G-D-A-V-D-Y-I-N-S-K-A"} +{"text": "### FUNCTION Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism ### SEQUENCE -M-K-R-S-K-V-E-R-Q-S-M-L-K-E-K-I-E-L-T-P-F-V-T-D-E-Q-L-A-K-E-F-H-V-S-I-Q-T-I-R-L-D-R-M-E-L-A-I-P-E-L-R-E-R-I-K-H-V-A-T-N-Q-W-N-E-T-V-K-A-L-P-L-E-E-V-I-G-E-V-I-D-L-E-L-D-E-R-A-I-S-I-M-D-I-T-P-D-L-V-F-S-R-N-K-I-A-R-G-H-H-I-F-A-Q-A-N-S-L-A-V-A-V-I-N-D-E-L-A-L-T-A-K-S-N-L-K-F-T-R-Q-V-N-E-G-E-R-V-I-A-K-A-I-V-K-G-K-D-N-R-D-R-T-I-V-E-V-S-S-Y-V-E-N-E-L-V-F-T-G-E-F-F-M-F-H-S-S-N-E-K-G-E-N"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-M-L-E-P-S-I-D-S-L-Q-K-R-I-K-S-K-Y-S-L-V-T-L-S-A-R-R-A-R-Q-L-S-E-T-N-Q-P-L-V-E-K-S-K-S-H-K-F-V-G-M-A-L-E-E-I-E-A-G-K-L-Y-I-E-N"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-F-K-N-K-L-K-D-Y-F-M-G-D-E-Y-E-Y-E-Y-V-D-E-D-N-Q-S-E-E-P-T-Q-K-E-A-K-V-N-P-K-N-V-V-N-L-S-S-V-Q-Q-S-N-S-R-V-V-L-I-E-P-R-N-Y-N-E-A-Q-E-I-A-D-N-I-V-N-R-R-A-V-I-I-N-L-Q-R-V-D-H-Q-Q-A-K-R-I-V-D-F-L-S-G-T-V-Y-A-V-K-G-D-I-Q-K-L-G-A-E-T-F-L-C-T-P-D-N-V-E-V-S-G-T-I-T-E-M-L-Y-E-Q-E-E-Y-D-K-G-W"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-T-M-K-D-I-V-R-E-G-H-P-S-L-T-R-S-A-A-V-V-E-V-P-L-S-K-D-D-K-Q-L-L-E-D-M-M-Q-F-L-K-N-S-Q-D-E-E-I-A-E-K-Y-E-L-R-A-G-V-G-I-A-A-P-Q-L-G-I-E-K-Q-I-I-A-I-H-F-E-D-I-D-G-K-L-Y-S-M-G-L-V-N-P-K-I-I-S-H-S-V-E-Q-S-Y-L-S-S-G-E-G-C-L-S-V-D-R-P-V-E-G-Y-V-P-R-H-A-R-I-T-I-K-A-T-D-I-N-D-Q-P-V-K-L-R-L-K-G-Y-P-A-I-V-F-Q-H-E-I-D-H-I-N-G-I-M-F-F-D-R-I-N-T-E-D-P-F-N-I-P-E-N-S-S-P-I-Q"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-F-K-V-L-Y-Q-E-L-P-N-E-V-P-I-R-E-R-T-K-S-L-Y-V-E-A-E-T-I-R-E-V-R-K-K-I-S-D-S-D-H-N-Y-N-I-E-F-V-Q-P-L-D-E-A-H-L-Q-Y-E-K-D-T-G-K-L-E-L-E-N-L"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-T-V-N-I-Y-G-A-S-C-S-S-T-R-K-A-R-Q-W-F-K-K-H-G-I-A-Y-K-E-R-N-I-L-R-Q-P-L-T-I-N-E-L-Q-E-I-L-R-M-T-V-E-G-T-D-E-I-I-S-T-R-S-K-I-F-K-E-L-N-L-N-L-D-E-L-P-L-Q-K-L-L-E-L-I-H-E-H-P-R-L-L-K-S-P-I-L-M-D-E-K-R-F-Q-V-G-Y-H-E-D-D-I-R-Q-F-L-P-R-K-T-R-E-H-L-W-L-Q-W-K-L-D-L-G-L-V-K-G"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-T-L-Y-T-S-P-S-C-T-S-C-R-K-A-R-A-W-L-E-E-H-N-I-P-F-T-E-R-N-I-F-S-E-P-L-S-L-D-E-I-K-E-I-L-R-M-T-E-D-G-T-D-E-I-I-S-T-R-S-K-V-F-Q-K-L-D-V-N-I-D-Q-L-P-M-K-N-L-F-N-L-I-Q-K-N-P-G-L-L-R-R-P-I-I-L-D-E-K-R-L-Q-V-G-Y-N-E-D-E-I-R-R-F-L-P-R-T-V-R-T-F-Q-L-R-E-A-Q-R-M-V-N"} +{"text": "### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-K-K-L-T-K-K-A-E-N-L-L-L-L-I-W-V-Q-A-F-L-A-L-A-G-S-L-F-Y-S-E-V-M-N-Y-V-P-C-E-L-C-W-Y-Q-R-I-L-M-Y-P-L-V-L-I-Y-G-V-A-A-I-K-K-D-I-S-F-A-L-P-G-L-F-M-S-G-I-G-L-L-V-S-T-Y-H-Y-L-V-Q-H-V-S-I-F-Q-E-V-G-G-A-C-S-G-S-V-P-C-N-V-I-Y-V-N-Y-F-G-F-I-S-I-P-F-M-A-G-V-A-F-L-I-I-F-V-L-H-L-L-I-L-R-E-Q-G-R-K-A"} +{"text": "### FUNCTION Possible metal-dependent hydrolase ### SEQUENCE -M-N-E-K-Y-P-I-G-E-F-Q-F-D-G-E-I-T-N-I-I-I-N-E-W-I-N-E-I-E-D-L-P-R-L-L-K-N-T-V-I-D-L-N-N-E-Q-L-D-T-S-Y-R-S-G-G-W-T-V-R-Q-V-I-H-H-L-A-D-S-H-M-N-A-Y-I-R-L-K-L-A-I-T-E-E-N-P-V-I-K-P-Y-D-E-K-E-W-A-E-L-Y-D-Y-N-L-P-I-E-I-S-L-S-L-I-E-A-L-H-K-R-W-C-S-L-L-R-D-L-S-P-T-D-M-E-R-T-F-K-H-P-E-S-G-S-I-S-I-G-K-N-I-G-I-Y-A-W-H-G-K-H-H-L-A-H-I-T-S-L-C-K-R-K-D-W"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-A-E-I-S-K-D-Q-V-K-H-V-A-H-L-A-R-L-E-L-D-D-E-A-V-E-K-M-S-D-E-L-S-A-I-I-D-F-A-E-Q-L-N-E-L-D-T-D-S-V-E-P-T-T-H-V-L-N-L-K-N-V-M-R-K-D-E-P-K-K-W-I-S-Q-E-D-A-L-R-N-A-P-D-H-K-D-G-Q-I-R-V-P-S-I-L-E"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-C-G-V-G-I-D-I-I-E-L-N-R-M-E-A-L-I-E-R-N-E-R-F-I-E-R-I-L-T-E-N-E-Q-R-K-F-Q-R-L-S-A-N-R-K-V-E-Y-I-A-G-R-F-A-A-K-E-A-F-A-K-A-V-G-T-G-I-G-K-V-S-F-K-D-I-E-I-I-N-N-D-Y-G-A-P-N-M-K-V-K-G-Y-N-D-N-V-I-H-L-S-I-S-H-S-K-T-Y-A-V-A-N-V-V-L-E-T-R-E"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-K-S-L-E-D-I-Q-G-T-E-D-H-Q-K-G-E-T-W-E-S-R-R-F-V-L-N-K-D-N-V-G-F-S-L-N-D-T-I-I-K-A-G-T-E-S-Y-F-W-Y-K-N-H-I-E-A-V-Y-C-I-E-G-E-G-E-V-E-K-K-D-T-G-E-V-W-Q-L-K-P-G-T-M-Y-L-L-N-D-N-D-K-H-Y-L-R-A-K-T-Q-M-R-M-V-C-V-F-N-P-A-L-V-G-T-E-T-H-D-E-D-G-V-Y-P-L-L-A-E"} +{"text": "### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate with acetyl coenzyme A ### SEQUENCE -M-A-E-K-L-K-V-D-T-D-E-Y-Y-F-R-R-P-T-K-E-D-G-G-P-V-W-E-L-V-R-E-I-G-N-L-D-L-N-S-S-Y-S-Y-V-L-W-C-E-V-F-A-E-S-S-I-V-V-E-H-K-E-T-Q-Q-I-V-G-F-I-S-G-F-M-H-P-E-K-E-D-T-L-F-I-W-Q-V-A-V-S-S-T-Q-R-G-K-G-L-A-T-K-M-L-L-Q-L-L-E-W-N-E-S-V-N-F-I-E-A-T-V-A-P-S-N-K-P-S-N-Y-L-F-L-G-L-A-R-K-I-H-T-N-W-K-I-S-D-Y-F-K-T-D-H-F-P-A-K-D-E-E-H-E-E-E-L-L-F-R-I-G-P-M-R-K-N-K-N-K-R-M-I"} +{"text": "### FUNCTION Possible metal-dependent hydrolase ### SEQUENCE -M-D-V-R-F-P-I-G-K-L-Q-V-P-E-K-V-T-I-E-D-I-H-E-W-L-K-Q-I-E-T-Y-T-N-R-L-G-E-T-V-N-S-L-N-D-E-E-L-S-K-T-Y-R-E-G-S-W-D-I-R-Q-L-V-H-H-I-A-D-S-Q-L-N-M-Y-Q-R-L-K-L-A-L-T-D-E-S-P-T-V-P-A-F-D-Q-E-K-W-A-I-Q-P-D-T-N-L-P-V-E-T-S-I-K-M-L-E-G-I-N-E-R-I-V-S-L-G-Y-R-L-T-E-E-Q-L-D-Q-S-F-V-H-Q-I-N-G-E-I-S-V-A-S-K-V-A-K-L-A-W-H-E-E-H-H-L-A-H-I-K-I-A-L-S-N-N-S-G-S"} +{"text": "### FUNCTION Nitric oxide-responsive transcriptional regulator ### SEQUENCE -M-N-L-K-K-Y-T-D-Y-A-L-R-V-L-I-F-T-G-L-K-S-D-Q-E-L-A-N-I-K-E-I-A-E-V-Y-Q-I-S-Q-E-H-L-R-K-V-V-H-E-L-T-K-M-E-L-V-V-T-I-R-G-R-N-G-G-I-K-L-A-K-P-A-S-E-I-N-I-G-L-L-I-R-Q-L-E-N-D-F-V-L-L-E-C-F-D-K-G-T-N-H-C-V-I-S-P-G-C-T-L-K-H-V-I-N-K-A-L-V-A-F-F-K-V-L-E-E-Y-T-L-E-D-L-I-K-N-E-E-E-L-L-A-L-M-G-I-E-K-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-F-M-A-N-E-A-N-I-E-R-K-W-L-V-V-D-A-E-G-Q-R-L-G-R-L-A-S-E-V-A-S-I-L-R-G-K-H-K-A-T-Y-T-P-H-A-D-T-G-D-N-V-I-I-I-N-A-D-K-I-E-L-T-G-N-K-I-N-D-K-M-Y-Y-R-H-S-N-H-P-G-G-L-K-E-R-N-A-Y-E-M-R-T-K-Y-P-E-Q-M-L-E-I-A-V-K-G-M-L-P-K-G-P-L-G-R-K-M-G-K-K-L-H-V-Y-R-G-A-E-H-N-H-Q-A-Q-K-P-E-V-Y-E-L-R-G"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-D-I-P-R-D-K-R-V-V-I-S-L-T-Y-I-Y-G-V-G-K-T-T-A-Q-Q-I-L-K-E-A-G-V-S-E-D-T-R-V-R-D-L-T-E-D-E-L-G-R-I-R-Q-A-V-D-Q-Y-N-T-E-G-D-L-R-R-E-V-S-L-N-I-K-R-L-I-E-I-G-S-Y-R-G-I-R-H-R-R-G-L-P-V-R-G-Q-K-T-K-N-N-S-R-T-R-K-G-P-R-K-T-M-A-N-K-K-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-E-V-E-G-T-V-T-D-T-L-P-N-A-M-F-K-V-E-L-E-N-G-H-T-V-L-A-H-V-S-G-K-I-R-M-H-F-I-R-I-L-P-G-D-K-V-T-V-E-L-S-P-Y-D-L-T-R-G-R-I-T-Y-R-Y-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-A-A-E-G-T-R-K-E-R-N-R-V-G-R-G-M-S-S-G-N-G-K-T-S-G-R-G-H-K-G-Q-K-A-R-S-G-G-G-V-R-P-G-F-E-G-G-Q-M-P-L-F-Q-R-L-P-K-R-G-F-T-N-V-N-R-K-E-Y-A-I-V-N-L-D-T-L-N-R-F-E-E-G-T-E-I-T-P-E-L-L-L-E-T-G-V-V-S-K-L-N-A-G-I-K-I-L-G-K-G-T-L-E-K-K-L-T-V-K-A-H-K-F-S-A-S-A-K-E-A-I-E-T-A-G-G-Q-S-E-V-I"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-T-K-P-D-K-N-V-I-R-K-K-R-H-N-R-V-R-R-T-L-S-G-T-A-E-R-P-R-L-N-V-Y-R-S-N-K-N-I-Y-A-Q-L-I-D-D-N-A-G-V-T-V-A-S-A-S-T-A-D-K-E-L-A-I-G-G-G-N-V-E-S-A-K-Q-V-G-A-A-I-A-K-R-A-I-D-K-G-Y-K-S-I-V-F-D-R-G-G-Y-L-Y-H-G-R-I-K-A-L-A-E-A-A-R-E-E-G-L-E-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-L-K-P-V-E-I-P-E-G-V-E-L-K-L-D-N-N-T-V-T-V-K-G-P-K-G-E-L-S-R-E-L-H-P-D-M-K-I-N-I-E-D-N-V-L-T-V-E-R-P-S-D-H-K-E-H-R-A-L-H-G-T-T-R-S-L-I-N-N-M-V-I-G-V-S-K-G-F-E-K-S-L-E-I-I-G-V-G-Y-R-A-Q-K-Q-G-D-K-T-V-I-N-A-G-Y-S-H-P-V-E-L-E-A-I-D-G-I-E-I-E-V-P-K-N-T-Q-I-T-V-K-G-I-D-K-E-L-V-G-A-I-A-A-N-I-R-A-I-R-P-P-E-P-Y-K-G-K-G-I-R-Y-T-D-E-Y-V-R-R-K-E-G-K-T-A-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-M-L-T-R-I-R-N-A-N-M-V-K-H-E-K-L-E-L-P-A-S-N-I-K-K-E-I-A-D-I-L-K-R-E-G-F-V-K-D-Y-E-L-I-E-D-N-K-Q-G-V-L-R-I-F-L-K-Y-S-A-N-E-D-K-V-I-S-G-I-K-R-I-S-K-P-G-L-R-V-Y-A-K-A-D-E-V-P-R-V-L-N-G-L-G-I-A-I-V-S-T-S-N-G-L-L-S-D-K-E-A-R-S-Q-A-V-G-G-E-V-L-A-Y-V-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-Q-K-R-P-Q-K-F-K-V-Q-E-Y-T-R-C-E-R-C-G-R-P-H-S-V-I-R-K-F-K-L-C-R-I-C-F-R-E-L-A-Y-K-G-Q-I-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-E-L-K-Q-K-Y-Q-D-E-I-V-S-S-L-M-D-K-F-N-Y-N-S-V-M-E-V-P-K-V-E-K-I-V-I-N-M-G-V-G-D-A-V-Q-N-S-K-A-L-D-S-A-V-E-E-L-S-L-I-S-G-Q-K-P-M-I-T-R-A-K-K-S-I-A-G-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-Q-K-L-V-A-V-S-L-P-R-V-R-D-F-R-G-I-S-K-K-A-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-N-Y-D-K-V-S-K-I-R-G-M-D-I-V-V-V-T-T-S-N-T-D-E-E-A-R-E-L-L-A-Q-L-G-M-P-F-Q-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-H-V-K-K-G-D-K-V-K-V-L-S-G-K-D-R-G-K-E-G-T-V-L-E-A-F-P-K-N-E-R-V-L-V-E-G-V-N-M-V-Q-K-H-A-K-P-S-Q-E-N-P-Q-G-G-I-L-N-I-E-A-P-I-H-V-S-N-V-L-P-V-D-P-K-S-G-E-P-T-R-V-G-Y-E-V-K-D-G-K-K-I-R-I-A-K-K-S-G-E-A-L-D-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-K-V-A-D-N-S-G-A-R-E-V-L-T-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-V-I-V-C-T-V-K-Q-A-T-P-G-G-V-V-K-K-G-E-V-V-K-A-V-I-V-R-S-K-S-G-A-R-R-K-D-G-S-Y-I-R-F-D-E-N-A-A-V-I-I-R-D-D-K-S-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-A-Q-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-T-E-R-N-D-R-K-V-Y-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-L-V-E-T-Y-K-F-H-K-L-Y-G-K-R-V-K-Y-S-K-K-F-K-T-H-D-E-N-N-V-A-K-N-G-D-V-V-R-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-V-T-E-E-A-V-I-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-Y-R-R-Q-H-R-G-K-M-R-G-Q-A-K-G-G-T-T-V-A-F-G-E-Y-G-L-Q-A-T-E-A-S-W-I-T-S-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-D-K-P-Y-T-A-K-P-L-E-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-V-V-K-P-G-K-I-M-F-E-I-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-T-K-F-V-K-R-E-E-I-G-G-E-S-N-E-G"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-Q-A-K-A-V-A-K-S-V-R-I-A-P-R-K-V-R-L-V-V-D-L-I-R-G-K-E-V-G-E-A-I-A-I-L-N-H-T-Q-R-G-A-S-P-V-V-E-K-V-L-K-S-A-I-A-N-A-E-H-N-Y-E-M-D-A-D-S-L-V-I-S-E-A-F-V-N-E-G-A-T-L-K-R-F-R-P-R-A-Q-G-R-A-S-R-I-N-K-R-T-S-H-I-T-V-V-V-T-E-K-K-E-G"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-A-D-D-H-L-M-K-K-I-E-V-L-N-T-D-D-K-K-Q-V-I-K-T-W-S-R-R-S-T-I-F-P-T-F-V-G-H-T-V-A-V-Y-D-G-R-K-H-V-P-V-Y-I-T-E-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-A-G-D-D-K-K-T-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-K-D-L-R-D-V-I-K-R-P-V-I-T-E-H-S-A-D-L-M-A-E-K-K-Y-T-F-E-V-S-P-K-A-N-K-T-E-I-K-D-A-V-E-T-I-F-G-V-K-V-E-K-V-N-T-M-N-Q-K-G-K-F-K-R-M-G-R-Y-G-G-Y-R-P-N-R-K-K-A-V-V-Q-L-T-A-D-S-K-E-L-D-F-F-E-A"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-K-E-K-I-R-I-R-L-K-A-Y-D-H-R-I-L-D-Q-S-A-E-K-I-V-D-T-A-K-R-S-G-A-K-V-S-G-P-I-P-L-P-T-E-K-S-V-Y-T-V-L-R-A-V-H-K-Y-K-D-S-R-E-Q-F-E-M-R-T-H-K-R-L-I-D-I-L-E-P-T-P-K-T-V-D-A-L-M-R-L-D-L-P-S-G-V-D-I-E-I-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-P-K-R-D-V-L-P-D-P-L-Y-K-S-K-L-V-T-R-L-I-N-Q-I-M-V-D-G-K-R-G-K-A-Q-K-I-L-Y-N-A-F-E-L-V-A-E-R-S-G-Q-N-A-M-E-V-F-E-Q-A-M-K-N-V-M-P-V-L-E-V-R-A-R-R-V-G-G-S-N-Y-Q-V-P-V-E-V-R-P-E-R-R-Q-A-L-G-L-R-Y-I-V-N-Y-S-R-L-R-G-E-K-T-M-E-E-R-L-A-N-E-I-L-D-A-S-N-N-T-G-A-A-V-K-R-R-E-D-M-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-T-N-E-E-M-I-S-A-I-K-E-M-S-V-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-A-A-G-A-A-G-G-A-V-E-E-E-K-T-E-F-D-V-V-L-T-S-A-G-A-S-K-I-K-V-V-K-A-V-R-E-I-T-G-L-G-L-K-D-A-K-D-L-V-D-N-A-P-K-P-I-K-E-G-V-S-K-E-E-A-E-E-V-Q-G-K-L-E-E-A-G-A-S-V-E-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-G-I-I-E-K-K-K-Q-V-V-E-E-I-A-E-K-F-R-A-S-Q-T-A-V-V-V-D-Y-R-G-L-D-V-A-E-V-T-A-L-R-K-E-L-R-E-A-G-I-E-F-K-V-Y-K-N-T-M-T-R-R-A-V-E-A-V-E-L-T-D-L-N-D-T-L-T-G-P-T-A-I-A-F-S-N-D-D-V-V-A-P-A-R-I-L-N-N-F-K-K-D-H-E-A-L-E-I-K-G-G-V-I-E-G-Q-V-A-T-L-D-Q-I-K-D-L-A-D-L-P-N-Y-E-G-M-V-S-M-L-L-S-V-L-Q-A-P-V-R-N-F-A-Y-V-T-K-A-V-A-E-Q-K-E-E-Q-G-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-I-K-L-V-K-L-Q-I-P-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-A-G-V-N-I-M-G-F-C-K-E-F-N-A-R-T-Q-D-Q-A-G-M-I-I-P-V-E-I-T-V-F-E-D-R-S-F-T-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-I-E-S-G-S-G-E-P-N-K-N-K-V-A-S-V-K-R-D-Q-V-K-E-I-A-E-T-K-M-P-D-L-N-A-A-D-V-D-A-A-M-R-M-V-E-G-T-A-R-S-M-G-I-T-I-E-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-G-N-R-E-I-F-D-Q-V-S-D-M-E-K-Q-I-G-E-L-Y-E-Q-L-G-D-L-K-V-K-L-S-D-L-L-E-E-N-H-R-L-A-H-E-N-H-H-L-R-H-H-L-E-E-Y-R-Q-D-G-D-T-D-S-K-Q-P-L-N-E-T-K-K-K-H-H-T-L-P-G-E-G-Y-D-N-L-A-R-L-Y-E-E-G-F-H-I-C-N-L-E-F-G-S-P-R-R-N-E-D-C-I-F-C-L-D-F-F-D-K-T-K"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Y-Y-P-E-P-I-T-K-L-I-D-S-F-S-K-L-P-G-I-G-P-K-T-A-A-R-L-A-F-F-V-L-N-M-K-E-D-D-V-L-N-F-A-N-A-L-V-S-A-K-R-E-L-S-H-C-S-V-C-G-H-I-T-D-Q-D-P-C-A-I-C-T-D-T-S-R-D-G-S-L-I-C-V-V-Q-D-P-K-D-V-I-A-M-E-K-M-K-E-F-H-G-K-Y-H-V-L-H-G-A-I-S-P-M-D-G-I-G-P-E-D-I-N-V-P-D-L-I-N-R-L-K-D-E-E-V-E-E-L-I-L-A-T-N-P-N-I-E-G-E-A-T-A-M-Y-I-S-R-L-V-K-P-S-G-I-R-T-T-R-I-A-H-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-L-E-G-R-R-D-V"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-K-G-N-M-N-N-M-M-K-Q-M-Q-K-M-Q-K-K-M-M-Q-A-Q-D-E-L-H-E-M-T-F-E-A-T-A-G-G-G-M-V-T-V-K-A-S-G-K-K-E-I-I-D-V-E-I-K-E-E-V-V-D-P-D-D-I-D-M-L-Q-D-L-I-L-A-A-T-N-D-V-L-N-Q-I-D-E-K-T-N-D-T-M-G-Q-F-T-K-G-M-N-M-P-G-M-F"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-D-N-V-L-R-N-K-K-D-F-S-N-L-F-K-N-K-S-T-Y-Y-S-S-F-F-I-I-Y-A-Y-K-N-N-L-G-W-L-R-Y-A-I-A-A-N-K-K-N-F-K-T-A-V-E-R-N-K-I-K-R-Q-I-R-S-I-V-R-G-L-E-N-K-N-I-P-V-D-I-L-I-I-P-K-N-N-F-F-K-T-D-F-L-N-K-K-N-D-L-F-N-L-I-V-K-I-R-L-N-I-K"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-G-Y-E-E-I-K-N-T-I-A-T-I-E-D-F-P-K-K-G-I-S-F-K-D-I-T-P-L-L-L-D-H-K-K-M-N-F-I-I-D-E-L-A-K-F-A-K-T-I-D-F-D-I-I-V-A-P-E-S-R-G-F-L-F-G-L-P-L-A-L-N-L-K-K-P-F-V-P-I-R-K-K-G-K-L-P-R-E-V-I-S-Q-E-Y-E-L-E-Y-G-K-A-T-I-E-V-T-K-N-D-I-P-A-N-S-K-V-L-I-I-D-D-L-I-A-T-G-G-T-T-V-A-I-Q-D-L-V-T-K-L-G-S-T-V-V-G-Q-A-Y-L-I-E-L-V-G-L-C-D-Y-E-K-L-Q-G-K-F-F-S-M-I-K-Y"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-N-E-M-K-I-K-L-F-S-Y-D-H-R-L-L-D-Q-S-V-R-K-I-I-K-S-S-Q-D-S-G-A-K-V-K-G-P-I-P-L-P-T-K-K-E-I-F-T-I-C-R-S-P-H-V-N-K-T-S-R-E-Q-F-E-R-R-T-H-Q-R-L-I-I-L-L-N-T-T-E-K-T-K-E-Y-L-K-N-I-I-I-P-S-G-V-D-I-Q-I-T-L-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-S-K-K-G-P-Y-I-E-P-S-L-M-K-K-V-Q-A-M-K-A-A-D-K-K-K-P-I-K-T-W-S-R-R-S-T-I-F-P-D-F-V-G-L-N-F-E-V-H-N-G-K-S-F-V-N-V-Y-V-T-E-D-M-I-G-H-K-L-G-E-F-A-Q-T-R-T-F-K-Q-H-T-S-N-R-K-D-L-A-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-Q-A-R-A-I-Q-K-N-I-H-V-S-P-R-K-A-K-L-V-C-D-L-I-R-N-K-P-V-T-N-A-L-S-I-L-E-N-T-N-K-K-T-A-V-F-L-K-K-L-L-H-Q-A-I-A-N-A-T-N-N-H-A-M-Q-A-D-K-L-Y-V-Y-H-V-V-A-N-Q-G-S-T-L-K-R-T-S-P-R-A-K-G-S-A-D-L-I-R-K-R-H-T-H-L-E-I-V-L-S-D-D-V-N-E-R-N-K-E-I-Q-A-I-K-D-R-I-K-K-R-A-A-N-N-K-G-Y"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-E-P-K-R-T-K-Y-R-R-P-H-K-V-S-Y-E-G-K-A-K-G-N-K-Y-V-A-F-G-E-F-G-L-M-A-T-N-G-A-W-I-S-N-R-Q-I-E-S-A-R-I-A-I-S-K-A-L-G-K-T-G-K-M-W-I-R-I-F-P-H-L-S-L-T-K-K-P-L-E-V-R-M-G-S-G-K-G-S-P-E-K-W-V-A-V-V-K-A-G-T-V-M-F-E-V-A-N-I-P-E-E-V-A-R-T-A-L-K-N-A-G-N-K-L-S-V-N-W-K-I-V-K-K-G-E-I-A-H-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-S-Q-V-N-T-T-R-D-S-R-R-K-I-L-Q-G-I-V-V-S-D-K-M-Q-K-T-I-V-V-Q-V-E-R-K-S-K-H-R-L-Y-K-K-L-V-I-T-H-K-K-Y-H-A-H-D-E-K-E-E-C-K-I-G-D-F-V-E-I-M-E-T-R-P-L-S-A-T-K-R-W-R-L-N-K-I-I-Q-K-A-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-F-M-T-K-L-N-V-A-D-N-T-G-A-K-Q-V-G-V-I-K-V-L-G-G-T-K-R-R-Y-A-S-V-G-D-I-V-V-V-S-V-K-K-A-Q-P-D-G-I-V-R-K-G-Q-V-C-K-A-V-I-V-R-V-K-K-N-I-T-R-S-S-G-N-S-L-S-F-D-D-N-A-C-V-I-I-K-E-D-K-T-P-R-G-S-R-I-F-G-P-V-A-R-E-L-R-D-K-G-F-S-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-R-L-K-K-G-D-K-V-R-V-I-S-G-S-E-K-G-K-E-G-I-I-L-Q-V-F-P-E-L-N-T-A-Q-V-E-G-V-N-V-R-K-R-H-K-K-A-N-Q-E-N-Q-E-G-G-I-V-D-I-A-V-P-L-N-M-S-K-L-A-L-I-D-N-K-A-K-G-K-T-T-R-I-K-Y-G-F-D-K-N-N-K-K-V-R-I-S-K-I-S-N-S-E-I-G-S-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-I-K-S-V-L-Y-D-K-Y-K-K-D-V-T-K-S-L-M-K-E-F-N-Y-K-S-T-M-E-I-P-R-L-E-K-I-V-I-N-S-G-L-G-D-A-T-S-D-S-K-I-V-E-I-G-L-K-E-L-H-L-I-T-G-Q-K-P-I-A-T-K-S-K-K-S-I-A-T-F-K-L-R-E-G-Q-A-I-G-A-K-V-T-L-R-R-E-N-M-W-N-F-L-T-K-L-I-S-I-A-I-P-R-I-R-D-F-R-G-L-S-T-K-S-F-D-G-N-G-N-Y-T-F-G-I-K-E-Q-I-I-F-P-E-I-V-Y-D-D-V-K-K-L-R-G-F-D-I-T-I-V-T-S-A-K-T-D-K-E-A-M-F-L-L-K-E-L-G-M-P-F-V-K-T-K-E-A-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-L-I-V-K-Q-K-K-H-P-K-F-K-V-R-A-Y-T-R-C-E-R-C-G-R-P-R-A-V-I-R-K-F-G-I-C-R-L-C-F-R-D-L-A-Y-K-G-A-I-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-Y-M-D-P-I-S-D-L-L-L-R-I-K-T-G-T-K-T-K-R-N-S-V-V-V-K-T-S-K-L-V-T-N-I-L-E-I-L-K-N-E-G-Y-I-E-G-F-K-T-E-S-I-G-K-N-K-N-Q-T-V-V-N-L-K-Y-R-N-N-V-S-S-I-T-G-L-K-Q-I-S-K-P-G-L-R-I-Y-S-E-A-Q-K-L-P-K-V-L-N-G-L-G-I-A-I-I-S-T-S-M-G-L-M-T-D-K-N-A-K-K-N-N-V-G-G-E-V-I-A-Y-V-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-N-R-L-L-S-I-P-S-G-V-N-V-E-V-E-K-S-L-V-K-I-T-G-K-L-G-T-L-S-V-P-F-D-S-K-K-L-S-V-L-N-K-D-S-M-V-I-V-K-R-A-N-D-E-K-E-T-K-M-L-H-G-T-T-N-A-N-I-N-N-A-L-I-G-V-N-S-G-H-T-K-K-L-K-I-V-G-V-G-Y-K-A-A-V-N-G-N-K-I-N-L-N-L-G-Y-S-H-P-I-D-L-E-I-P-A-G-L-N-V-T-C-P-Q-A-T-E-V-V-I-T-G-A-D-K-A-V-V-G-Q-F-A-A-V-I-R-S-K-R-P-P-E-P-Y-K-G-K-G-V-A-Y-S-N-E-V-I-I-R-K-V-G-K-T-A-E-G-S-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-K-N-I-N-L-N-R-K-E-K-R-T-E-R-H-K-K-V-L-R-K-F-R-K-I-D-N-D-L-P-R-L-R-I-T-K-T-N-Q-H-I-F-A-Q-L-L-D-D-N-K-N-I-V-I-A-S-S-S-S-V-Q-L-K-L-A-N-G-N-I-E-N-S-K-K-V-G-E-D-I-A-K-K-A-I-S-K-K-I-K-A-I-N-F-D-C-G-G-S-K-Y-H-G-R-V-S-A-L-A-D-A-A-R-K-T-G-L-K-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-E-N-L-K-S-K-E-G-S-R-H-K-T-K-R-V-G-R-G-F-G-S-G-I-G-K-T-S-T-R-G-S-K-G-Q-K-S-R-K-S-G-H-T-R-P-G-F-E-G-G-Q-T-T-L-Y-R-R-I-P-K-I-G-F-N-N-K-N-F-A-N-N-Y-N-V-V-T-L-N-N-I-V-K-L-N-L-A-N-V-D-K-K-V-L-V-E-K-G-L-I-E-D-N-K-L-P-I-K-V-I-G-T-A-T-I-S-K-P-I-S-V-S-A-H-K-F-S-K-G-S-V-A-T-L-E-K-S-K-S-K-F-V-V-I-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-E-G-K-I-T-L-K-G-K-V-V-T-A-L-Q-G-G-Q-F-K-V-L-L-E-N-N-V-E-I-I-A-N-V-S-G-K-I-R-V-Y-K-I-Q-I-L-K-G-D-T-V-E-V-E-L-S-P-Y-D-L-T-R-G-R-I-I-Y-R-I-S"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-L-G-V-D-I-P-N-N-K-R-V-V-I-S-L-T-Y-I-F-G-I-G-K-S-R-S-Q-E-I-L-S-K-A-K-I-D-E-N-K-K-V-S-A-L-S-E-E-E-L-A-T-I-R-K-I-A-S-E-Y-V-I-E-G-D-L-R-R-E-V-A-M-N-I-K-R-L-M-E-I-G-S-Y-R-G-I-R-H-R-R-N-L-P-V-R-G-Q-R-T-K-C-N-A-R-T-R-K-G-P-R-K-T-V-A-N-K-K-I-E-T-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-E-W-K-I-Y-K-E-E-F-D-K-K-A-E-V-K-L-E-W-L-D-S-E-F-N-K-I-K-S-G-R-P-N-P-K-I-L-D-H-V-M-V-E-A-Y-G-D-K-S-K-L-F-E-I-A-N-M-Q-V-V-E-G-K-Q-I-V-V-K-P-Y-D-K-T-L-L-H-D-I-N-S-A-I-Q-K-E-N-L-G-L-S-V-Q-V-D-A-D-S-L-R-I-I-F-P-S-P-T-E-E-T-R-K-A-S-V-K-K-V-K-E-F-S-E-Q-V-K-V-E-I-R-N-I-R-K-D-V-H-H-K-I-K-D-D-K-E-L-R-E-D-E-L-K-W-Y-E-E-D-L-D-K-L-T-R-E-W-N-A-K-V-D-K-A-F-A-E-K-E-K-E-L-M-T-I"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-R-V-K-T-G-P-T-T-R-R-R-R-K-S-W-L-K-K-A-E-G-A-W-G-I-N-S-T-S-Y-R-N-A-K-Q-T-V-M-Q-A-S-K-Y-A-Y-R-D-R-K-N-K-K-R-D-F-R-K-L-W-I-A-R-I-N-A-A-I-R-K-E-N-Y-T-Y-S-A-F-M-H-K-L-K-Q-K-E-I-A-I-N-R-K-M-L-S-E-L-A-I-Q-N-P-E-E-F-K-K-F-V-H-S-V-M-L-K"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-Q-N-L-N-S-K-I-L-A-I-D-F-G-T-K-I-I-G-T-A-I-N-D-I-N-L-N-L-C-L-P-Y-C-E-I-T-N-N-E-L-K-F-K-K-I-L-E-I-V-E-E-E-N-I-K-E-I-V-I-G-F-P-K-T-Q-N-S-Y-V-S-E-R-H-Q-L-I-I-D-F-K-N-Q-L-S-E-L-L-K-N-K-N-I-E-I-C-F-F-D-E-S-Y-S-T-K-S-S-K-E-S-L-M-N-F-N-V-K-T-S-K-L-K-K-N-K-D-M-I-A-A-S-I-I-L-E-N-Y-L-A-S-K-K"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-N-M-Q-K-M-L-Q-Q-A-K-A-L-Q-S-K-M-E-K-K-I-K-E-F-E-Q-E-E-F-E-F-V-Y-Q-K-S-I-T-I-Q-I-K-G-N-Y-E-I-I-K-M-D-I-N-K-E-L-I-D-P-E-D-K-T-M-L-E-E-M-I-S-E-A-I-N-E-A-I-S-A-I-T-E-E-K-E-K-I-T-K-G-A-M-P-F"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-K-K-I-I-Q-F-K-D-N-L-S-S-E-I-S-E-Q-I-K-S-S-K-S-F-I-I-F-E-Y-L-G-L-D-A-A-T-I-T-K-L-R-K-D-L-F-K-T-G-S-K-L-L-V-L-K-N-N-I-L-R-R-A-L-E-K-A-N-I-K-E-F-G-D-L-V-G-P-N-A-I-V-W-G-T-E-D-E-I-A-P-L-K-E-V-F-N-L-T-K-D-N-E-C-I-K-I-K-G-S-Y-V-E-G-T-F-L-D-A-Q-K-T-M-S-I-A-S-L-P-N-R-E-G-L-Y-S-M-L-L-S-C-L-T-G-P-I-R-G-V-L-Y-A-L-K-A-V-S-E-T-K-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-L-S-A-K-D-I-I-D-S-L-K-E-M-S-M-L-E-I-K-D-L-I-E-A-I-E-T-E-F-G-V-S-A-A-A-P-V-A-V-A-A-A-P-A-G-G-A-A-A-P-S-E-V-T-V-T-L-K-D-V-G-G-N-K-V-A-V-I-K-V-V-R-E-I-T-G-L-G-L-M-E-A-K-A-L-V-D-N-A-P-S-K-V-K-E-G-V-K-L-A-D-A-E-N-M-K-K-Q-F-A-E-A-G-A-T-V-E-W"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-F-K-K-L-D-P-S-P-K-W-I-V-Y-D-N-N-P-V-M-H-K-P-I-E-D-V-V-F-P-L-T-K-E-D-E-H-V-I-S-Q-M-L-S-Y-V-D-A-S-Y-E-G-E-A-D-K-Y-D-I-R-A-G-I-G-I-A-A-I-Q-L-G-C-P-K-K-I-I-Y-I-H-L-D-D-K-N-G-E-H-K-Y-L-M-A-N-P-K-I-I-K-E-S-T-S-K-M-Y-L-K-N-G-E-G-C-L-S-V-K-K-D-H-K-G-L-S-I-R-K-S-I-V-W-V-K-G-I-D-L-F-T-N-K-E-I-E-V-K-A-T-D-L-L-A-A-C-F-Q-H-E-V-D-H-N-N-N-K-F-Y-Y-N-R-I-N-E-S-D-P-Y-Y-V-E-K-N-W-E-E-I"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-E-E-K-N-K-K-G-K-I-I-I-I-S-G-P-S-G-V-G-K-K-T-I-I-D-Q-V-I-N-N-V-D-L-N-L-T-Y-S-I-S-M-T-T-R-L-P-R-E-H-E-K-N-G-V-D-Y-F-F-V-S-E-E-E-F-N-S-A-I-E-K-G-E-L-L-E-W-A-E-F-A-N-N-K-Y-G-T-P-I-K-N-L-Y-K-L-I-G-E-N-K-N-V-I-L-E-I-E-V-Q-G-A-T-K-V-K-D-I-L-N-R-E-D-Y-I-S-I-F-L-I-P-P-S-I-R-E-L-K-R-R-L-K-I-R-D-T-E-T-K-E-K-I-K-Q-R-I-K-R-A-K-V-E-L-K-L-Q-N-E-Y-D-F-I-I-L-N-D-D-A-K-N-A-A-D-K-L-R-H-I-L-Y-E-K-V-L-E-K-K"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-I-K-K-I-Y-L-A-G-G-C-F-W-G-I-E-Q-Y-Y-N-L-N-Q-K-I-I-S-T-N-V-G-Y-L-N-S-K-I-D-N-P-T-Y-K-D-V-C-N-N-I-T-D-A-V-E-A-V-E-L-T-Y-D-D-Q-V-I-S-L-N-E-I-I-D-L-L-F-K-V-I-D-P-T-S-I-N-K-Q-G-N-D-I-G-R-Q-Y-R-T-G-I-Y-S-R-D-S-N-E-L-M-A-I-Q-E-K-I-N-E-L-Q-N-N-Y-S-K-L-I-Q-T-E-V-M-L-V-D-N-Y-Y-L-A-E-E-Y-H-Q-K-Y-L-E-K-N-P-N-G-Y-C-H-I-N-L-K-A-K"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-K-I-I-C-F-G-K-I-K-D-K-N-I-T-A-L-I-N-E-Y-L-S-K-I-N-H-F-T-N-L-T-I-V-E-L-S-E-E-K-I-N-N-E-N-S-I-G-E-I-E-E-A-L-K-K-E-S-K-K-L-I-P-Y-L-E-N-S-F-N-V-L-L-D-I-K-G-V-Q-M-D-S-I-K-F-A-N-S-I-N-Q-N-L-I-I-S-K-D-I-N-F-Y-I-G-S-S-H-G-I-S-E-S-I-K-N-K-F-N-L-K-L-S-F-S-E-L-T-F-N-H-Q-I-F-R-L-I-L-L-E-Q-I-Y-R-A-F-S-I-L-N-N-T-K-Y-H-K"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-I-F-E-V-G-S-K-Q-Y-K-V-Q-K-G-D-V-I-Y-V-E-K-Q-D-K-K-V-G-E-S-I-S-F-D-K-V-L-M-V-D-A-T-I-G-K-P-Y-I-K-N-A-T-V-S-C-K-V-E-K-Q-G-K-Q-K-K-I-F-I-I-K-H-K-R-Y-T-R-S-L-K-R-Q-G-H-R-Q-P-Y-T-K-L-V-V-T-G-I-N-V-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-Q-E-L-K-A-S-L-V-K-K-Y-G-G-N-S-N-N-T-G-K-V-E-V-Q-I-A-I-L-S-A-E-I-E-S-L-T-K-H-I-V-A-N-K-K-D-Q-I-S-K-R-G-L-F-Q-K-V-S-K-R-R-S-L-L-S-Y-L-K-N-T-D-I-V-R-Y-R-Q-I-L-K-D-L-D-I-R-G-N"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-I-L-V-V-N-K-K-L-H-F-N-Y-E-V-L-E-K-I-E-A-G-I-E-L-K-G-V-E-V-K-S-I-H-L-N-N-A-N-I-S-D-S-Y-V-I-F-K-R-N-E-A-Y-I-L-N-M-N-I-A-P-Y-S-H-G-N-I-Y-N-V-D-P-L-R-T-R-K-L-L-L-H-K-N-E-I-I-K-Y-Q-M-R-I-K-K-E-S-L-T-M-V-P-S-K-I-Y-W-R-K-N-K-L-K-V-E-I-A-L-A-K-G-K-K-Q-F-D-K-R-Q-T-I-K-D-R-D-N-S-R-E-A-R-K-H-I-R-V"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-F-D-V-Q-I-F-D-E-K-K-F-L-S-K-K-D-I-S-L-I-K-K-V-S-K-F-I-F-I-E-E-K-L-K-N-K-I-I-F-E-L-H-I-I-D-N-N-E-S-Q-K-I-N-K-Q-Y-R-N-K-D-Y-P-T-D-V-I-S-F-S-F-W-E-E-G-L-L-K-T-A-L-L-G-E-I-Y-L-S-Y-E-K-V-V-S-Q-A-E-E-F-K-H-S-F-E-R-E-L-G-F-L-V-S-H-G-I-Y-H-L-L-G-Y-D-H-E-E-E-D-E-A-K-I-M-F-G-K-Q-Y-Q-V-L-K-L-C-G-L-G-S-V-N-D"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-S-Q-I-I-H-A-K-D-L-R-P-G-N-T-F-I-Y-K-N-N-L-Y-L-V-I-E-N-S-F-N-K-T-A-M-R-E-G-I-V-K-C-K-V-K-N-L-R-T-S-S-I-T-V-E-V-L-T-G-E-K-L-E-R-A-I-I-D-K-V-K-A-M-Y-S-Y-A-D-K-N-T-L-V-F-M-D-G-E-S-F-E-Q-I-E-I-D-A-N-K-L-K-W-E-K-N-F-I-V-D-G-S-E-V-S-I-L-K-Y-G-E-E-V-L-N-V-S-L-P-D-Q-V-S-L-L-V-D-F-A-E-E-A-V-Q-G-N-T-V-Q-T-A-M-K-K-A-R-L-E-T-G-L-E-I-E-V-P-Q-F-I-K-T-G-E-K-I-I-V-N-T-V-D-G-K-Y-V-G-R-D-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-K-Y-L-V-V-G-L-G-N-P-G-L-E-Y-E-K-T-K-H-N-V-G-F-M-C-I-D-E-L-L-K-E-H-T-L-F-L-N-N-S-K-F-N-G-Q-F-V-K-V-D-Q-P-E-D-Q-I-F-I-A-K-P-M-T-Y-M-N-N-S-G-E-F-V-Y-E-I-C-K-F-Y-K-I-H-E-Q-N-I-L-V-I-Y-D-D-I-D-T-D-V-G-K-I-R-V-K-A-K-G-S-S-G-G-Q-N-G-I-K-S-I-I-S-K-M-N-T-E-K-I-K-R-I-R-I-G-I-G-K-P-V-H-N-L-T-H-H-V-L-T-K-F-S-A-E-D-S-I-K-V-Q-Q-A-I-I-K-A-K-D-A-C-N-E-F-L-N-H-V-D-F-D-K-I-M-N-K-F-N-V"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-E-K-K-T-T-K-K-A-T-A-S-K-T-T-T-T-K-K-A-A-A-E-K-T-E-I-K-E-T-K-K-T-T-T-T-K-T-S-T-A-K-K-A-T-T-A-S-V-E-K-T-E-V-K-E-T-K-K-S-S-D-N-K-K-E-F-N-P-Q-D-R-P-F-A-K-Y-N-R-G-Y-P-N-K-Q-G-R-R-K-K-F-C-K-L-C-A-K-G-Q-E-H-V-D-Y-K-D-V-E-L-L-Y-K-Y-L-T-P-N-L-K-I-A-S-R-K-I-T-F-A-C-S-K-H-Q-T-R-V-S-N-A-I-K-R-A-R-I-V-A-L-I-P-F-V-R-D"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-P-K-Y-E-I-M-L-V-V-D-G-S-I-E-E-S-K-A-T-A-V-A-N-D-L-K-S-I-L-K-K-S-T-D-L-K-L-E-K-M-G-L-K-D-L-A-Y-P-I-N-K-K-S-R-G-Y-Y-Y-L-F-N-F-Y-N-E-D-P-A-S-I-Q-E-F-R-R-V-T-L-L-K-K-E-V-L-R-H-L-I-I-N-L-E-K-D-Y-G-Y-K-A-K-T-N-P-K-K-I-V-R-S-Q-F-R-A-E-R-Y-K-R-I-K-E-Q-V-L-A-E-Q-E-K-I-R-K-E-R-D-N-T-P-V-K-L-T-D-V"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-H-M-S-N-V-K-I-E-R-Y-E-S-I-I-K-D-L-I-S-H-A-I-T-T-L-V-Y-D-D-L-I-K-Q-A-T-V-H-Y-V-T-L-S-K-D-K-S-I-A-K-V-Y-I-S-C-Y-D-K-T-I-I-D-K-I-L-K-K-I-N-G-A-S-G-F-F-R-T-I-L-A-K-N-L-N-L-R-K-A-P-A-I-V-F-L-N-D-E-S-I-D-K-I-D-E-I-N-S-L-L-E-Q-I-K-G-K"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-A-Q-K-M-T-N-E-Q-I-L-K-Y-V-Q-S-K-Q-I-R-K-D-I-P-E-F-R-S-G-D-T-I-I-V-H-N-K-I-I-E-N-N-K-S-R-I-Q-K-F-E-G-V-V-I-R-R-R-G-S-G-L-S-E-T-I-I-V-R-K-E-S-S-G-I-G-V-E-R-I-F-Q-L-H-S-P-Q-I-E-K-I-E-V-I-R-L-G-K-V-R-R-A-Y-L-T-Y-L-R-E-R-S-G-K-S-A-R-I-K-E-R-R-P-A-K-A-V-E-K-T-S-K-P-A-S-A-K-K-P-A-A-K-A-N-K-K"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-E-N-K-R-F-F-I-V-Y-Y-S-S-K-S-N-N-T-H-R-F-M-L-K-L-N-C-K-C-L-R-L-P-I-E-Q-K-D-E-P-D-E-I-L-E-S-K-I-P-T-V-N-H-P-F-I-L-L-T-P-T-Y-A-G-G-L-G-K-L-K-G-A-V-P-K-P-V-K-K-F-L-N-N-P-V-N-R-N-N-C-K-A-V-I-A-S-G-N-T-N-F-N-D-T-Y-C-I-A-G-D-I-I-S-Q-K-L-Q-I-P-F-L-Y-K-F-E-L-L-G-T-N-S-D-V-E-N-V-I-K-I-G-N-E-F-W-E-K-N-N-F"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-Q-K-T-T-F-V-K-N-E-A-A-L-A-N-K-K-W-Y-V-I-D-A-S-N-L-I-L-G-K-L-A-V-E-A-A-N-I-L-R-G-K-N-K-V-D-F-T-P-N-V-D-C-G-D-Y-L-I-I-I-N-S-D-K-I-V-L-S-S-D-K-A-D-R-E-K-W-Y-T-H-S-G-Y-I-G-G-L-K-E-K-S-G-R-L-M-I-E-K-Y-S-D-K-L-I-Y-G-A-I-K-G-M-L-P-K-N-T-L-S-R-Y-L-I-K-K-L-F-I-Y-K-D-A-N-H-K-Q-A-A-Q-K-P-M-E-I-K-L-N"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-E-E-K-N-H-I-D-H-Y-A-N-A-L-Y-S-I-W-L-E-L-D-K-K-N-K-I-I-F-T-S-S-A-K-D-I-Y-F-S-L-K-N-N-Y-E-M-V-H-I-I-D-S-N-I-I-S-K-E-E-K-T-K-I-L-N-K-I-F-F-D-L-S-K-S-I-S-N-I-Y-L-K-N-F-L-F-V-L-N-D-N-N-F-F-K-R-I-L-E-I-F-I-S-F-F-Q-K-L-D-E-H-Q-N-F-L-F-I-R-I-Y-S-P-F-V-V-E-K-K-L-L-E-K-I-E-H-L-F-S-I-K-T-G-K-R-V-R-Y-E-N-I-I-D-K-S-L-I-G-G-M-K-I-M-F-G-N-D-V-Y-D-Y-S-I-K-G-K-I-D-Q-I-K-W-N-I-E-N-N-K-E-V"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-E-T-I-N-N-V-F-D-S-V-I-S-L-Q-S-A-I-P-D-N-S-Q-I-I-N-Q-I-F-P-N-V-Y-V-L-I-A-H-V-I-S-L-I-F-L-L-L-L-V-I-R-L-A-W-K-P-T-K-S-Y-I-E-A-R-T-K-E-I-Q-R-K-M-E-A-A-E-K-A-Q-L-E-S-E-K-N-L-H-I-S-R-I-K-L-L-E-S-K-N-T-A-A-E-I-I-E-N-A-E-L-D-A-E-K-T-K-K-K-I-E-A-V-A-L-N-K-A-S-Q-I-E-S-E-G-Y-S-K-I-K-K-Q-E-L-E-L-E-K-R-K-N-L-E-V-S-K-L-A-L-E-T-A-G-I-F-L-S-K-K-I-D-E-E-E-N-K-K-I-I-D-D-I-V-N-D-L-T-A-K-L-E-S-S-S-K-E-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-N-L-K-R-N-K-Q-N-R-A-R-H-T-V-V-H-S-Q-T-S-A-V-K-T-Q-I-K-K-T-Q-A-S-K-S-Q-K-D-L-S-L-A-Y-K-K-I-D-S-A-L-A-K-G-I-I-K-Q-N-K-A-D-R-L-K-S-R-L-A-L-N-V-A-R"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-P-S-F-I-K-S-C-F-S-S-N-D-W-I-T-D-D-K-K-E-I-C-F-I-G-R-S-N-V-G-K-S-S-L-I-N-A-L-A-N-A-K-I-A-K-T-S-N-T-P-G-R-T-Q-L-A-N-F-Y-D-F-D-K-F-R-L-I-D-L-P-G-Y-G-Y-A-K-V-S-K-S-K-H-F-E-L-S-K-I-I-S-E-Y-I-Y-L-R-K-N-L-V-A-V-F-Q-I-I-D-I-S-V-I-T-D-L-D-L-Q-M-S-E-L-L-S-N-R-F-N-Q-H-Y-I-V-L-N-K-A-D-K-E-A-K-S-Y-F-D-N-N-F-A-K-I-A-A-K-L-K-K-D-K-E-N-I-V-C-V-S-A-K-N-K-T-N-I-P-N-L-K-K-L-I-G-S-V-I-L"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-S-I-N-V-K-S-V-I-E-A-A-L-F-I-A-G-N-E-G-V-H-K-D-K-L-K-S-I-S-R-L-S-V-Q-D-F-E-A-V-M-E-E-M-I-F-E-Y-E-K-D-P-Q-R-G-L-V-V-R-K-V-G-E-N-Y-K-L-F-T-K-P-D-I-S-K-I-V-A-S-G-F-G-I-K-Q-K-N-P-L-N-Q-G-M-I-E-T-L-A-I-I-A-Y-N-H-P-C-T-R-S-Q-I-H-E-L-R-K-T-D-P-T-P-M-L-E-K-L-I-E-I-G-L-V-E-E-A-G-R-S-E-A-V-G-K-P-Y-L-Y-Q-V-T-P-K-F-Y-D-I-F-G-L-D-S-I-K-D-L-P-E-I-V-L-P-E-Q-K-I-E-E-L-T-Y-E-E-E-I-N-F-F-D-T-N-R-E-D-N-G-D-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-N-R-A-T-K-R-E-I-L-P-D-P-V-Y-N-S-R-L-V-T-K-A-I-N-A-I-M-L-E-G-K-K-G-L-A-Q-Q-I-V-Y-Q-S-F-D-L-I-K-K-K-T-N-E-D-G-I-E-V-F-K-K-A-L-E-N-I-M-P-S-L-E-L-R-V-R-R-V-A-G-S-N-F-Q-V-P-T-V-V-S-K-E-R-K-Q-T-L-G-L-R-W-L-I-L-S-A-R-K-R-N-E-K-S-M-I-E-K-L-A-A-E-I-I-D-A-S-K-G-T-G-A-A-F-K-K-K-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-L-R-F"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-A-Q-L-I-R-H-D-R-K-D-K-F-K-K-S-K-S-P-A-L-M-Y-T-Y-N-S-L-K-K-K-R-T-Y-N-P-S-P-Y-K-R-G-V-C-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-Y-A-K-V-K-L-T-N-G-Y-E-V-L-A-Y-I-P-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-E-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-T-S-G-V-E-K-R-R-Q-Q-R-S-G-Y-G-A-K-R-P-K-E-K-K-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-L-L-V-A-F-K-D-P-R-I-T-R-I-A-K-V-N-L-I-G-G-Q-A-K-P-G-P-Q-L-A-S-I-G-I-N-M-G-E-F-T-K-Q-F-N-D-Q-T-K-D-K-N-G-E-V-I-P-C-I-I-T-A-F-K-D-K-S-F-T-F-E-I-K-T-T-P-V-T-M-L-L-K-K-A-A-N-I-K-V-G-A-K-N-S-K-T-E-T-V-A-T-I-S-R-E-K-A-L-E-I-A-K-T-K-L-V-D-T-N-A-N-D-E-E-A-V-L-R-M-V-A-G-S-A-K-Q-M-G-I-K-I-E-G-V-D-P-V-V-H-K-D-G-K-K-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-T-L-G-I-T-E-V-K-K-G-M-V-L-K-V-E-G-D-L-Y-S-V-V-K-T-E-F-V-N-P-G-K-G-S-A-F-I-R-T-K-L-K-N-L-T-R-N-S-S-I-E-R-T-F-K-A-A-E-K-L-E-S-V-E-L-E-K-R-N-M-T-I-C-Y-T-E-G-D-D-I-I-F-M-D-S-N-D-F-E-Q-M-P-V-S-K-E-Y-V-E-D-I-L-P-F-L-K-E-E-T-P-M-E-V-T-F-Y-E-G-K-P-I-G-V-I-P-P-N-F-S-I-L-E-V-T-Y-A-E-E-G-L-K-G-D-T-S-G-T-A-Q-K-R-I-T-V-E-T-G-G-E-I-N-V-P-I-F-V-K-Q-G-D-V-I-K-I-D-L-R-D-L-T-Y-V-E-R-V-S-K"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-L-T-K-G-S-K-V-V-N-V-G-I-A-D-M-Q-G-A-Q-S-P-E-I-L-R-T-T-L-G-S-C-I-G-V-V-F-Y-A-P-D-K-K-I-G-A-M-A-H-F-M-L-S-K-D-P-S-G-K-D-S-Q-K-N-P-F-K-Y-A-E-T-A-I-P-L-L-I-K-K-M-N-E-M-G-C-N-P-G-E-Y-S-V-R-L-F-G-G-A-S-M-F-K-G-V-Q-S-S-F-L-Q-N-I-G-E-Q-N-I-L-T-A-R-A-I-L-E-Q-S-K-I-P-L-I-L-E-D-V-G-G-N-D-G-R-T-I-S-L-Y-L-D-D-G-R-V-L-L-K-K-G-G-F-E-K-Y-L-Y-K-V-R"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-D-F-E-K-V-K-S-I-I-V-E-Q-L-G-V-D-E-S-E-V-T-P-E-A-H-F-I-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-G-I-E-I-S-D-E-D-A-E-K-I-Q-T-V-G-D-V-T-K-F-I-D-N-L-K-S"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-D-K-I-K-N-F-S-E-I-L-S-N-M-G-S-F-R-E-K-M-E-E-V-K-K-R-I-A-S-I-R-V-V-G-D-A-G-A-G-M-V-T-V-T-A-S-G-E-G-Q-I-T-N-V-F-I-N-K-Q-L-F-D-A-D-D-N-K-M-L-E-D-L-V-M-A-A-T-N-D-A-L-K-K-A-K-E-A-T-A-Y-E-F-Q-S-A-S-G-G-L-D-F-S-E-I-S-K-M-F-G-G-K-F-G"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-G-I-E-I-Q-T-K-P-F-G-K-M-Q-V-S-E-R-Q-I-L-S-F-P-E-G-L-L-G-F-E-E-Y-K-K-F-A-L-I-E-E-E-E-E-S-V-F-K-W-L-Q-S-T-E-E-V-D-L-A-F-V-V-I-P-P-S-L-F-K-K-E-Y-K-P-L-I-P-E-Q-E-L-L-G-I-G-I-N-E-I-K-E-S-L-T-L-V-I-V-T-V-P-G-E-D-P-S-M-M-T-A-N-T-Q-G-P-I-L-I-N-K-E-T-L-I-G-K-Q-F-I-S-R-N-E-S-H-S-V-R-E-K-I-L-E-S-A-A-V-E-I-G"} +{"text": "### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-V-L-A-R-R-T-N-E-S-I-M-I-G-D-D-I-E-I-V-I-V-D-I-K-G-D-Q-V-K-I-G-V-K-A-P-R-D-V-S-V-H-R-A-E-V-Y-K-D-I-Q-E-E-N-K-K-A-A-E-T-K-I-K-P-A-D-L-G-K-I-G-N-I-L-K-K-K-D-S-G-K-K-E"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-S-E-K-D-I-R-R-T-K-R-R-N-A-A-N-S-Q-N-R-S-R-L-R-T-Q-A-K-K-V-L-K-A-I-K-E-K-D-Q-K-A-A-M-T-L-F-I-E-Y-T-S-L-L-D-K-A-A-K-T-N-L-I-H-S-K-N-A-D-R-K-K-S-R-M-A-K-R-L-N-S-S-A-A"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-F-S-K-S-L-L-L-I-A-F-G-G-T-I-G-S-I-F-R-Y-L-L-Q-Y-W-F-G-N-V-L-G-Y-S-L-P-W-G-T-L-T-A-N-L-L-G-S-F-L-I-G-V-V-Y-A-I-S-D-R-F-P-L-F-D-P-Q-W-K-F-L-L-A-S-G-F-C-G-G-F-T-T-F-S-T-F-S-Y-E-T-F-Q-M-L-K-S-G-H-Y-I-L-F-L-G-Y-I-C-L-S-V-V-G-G-I-G-F-A-F-A-G-V-W-M-I-K-N-F"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-A-K-K-V-V-K-Q-I-K-L-Q-V-E-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-A-G-L-N-I-M-E-F-C-K-Q-F-N-E-R-S-K-A-Q-I-G-L-K-L-P-V-V-I-T-V-F-S-D-R-S-F-T-F-I-T-K-S-P-P-A-A-L-L-V-K-K-A-I-G-L-E-T-G-S-A-T-P-H-T-H-K-V-G-K-I-T-R-K-Q-L-E-E-I-A-K-T-K-M-E-D-L-N-A-N-D-I-D-A-A-V-N-I-I-A-G-T-C-R-S-M-G-V-T-V-E-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-N-Q-E-K-I-E-A-V-A-L-L-K-G-K-L-E-T-R-N-N-F-I-L-A-C-Y-S-G-L-T-V-E-E-I-T-G-L-R-A-Q-L-R-K-E-G-S-E-M-K-V-L-K-N-N-L-F-L-R-A-L-K-E-S-G-A-H-K-D-K-N-I-T-F-G-S-E-Y-Q-G-P-L-A-A-I-F-A-K-D-N-L-P-A-I-A-K-V-C-K-D-F-A-K-N-N-K-N-L-I-V-K-A-G-Y-M-D-G-S-V-L-D-A-N-G-V-D-A-I-A-G-L-P-S-R-E-Q-L-L-A-Q-I-A-G-G-I-N-G-P-A-R-T-I-A-S-G-I-N-Q-I-I-A-S-L-A-R-A-I-Q-A-T-A-E-K-N-N-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-T-E-A-L-L-E-Q-I-G-K-L-T-L-V-E-A-A-D-L-V-K-K-M-E-D-K-F-G-I-S-A-A-A-P-V-A-V-A-A-V-G-A-A-P-A-G-A-G-A-A-E-E-A-S-T-F-N-V-I-L-K-G-F-D-S-A-K-K-I-E-V-I-K-L-V-R-E-I-T-G-L-G-L-A-D-A-K-G-L-V-E-A-G-G-K-A-V-K-E-G-V-A-K-A-E-A-D-D-L-K-K-K-F-E-G-A-G-A-Q-I-E-L-K-A-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-R-G-K-V-E-P-R-K-I-T-P-D-P-V-Y-N-D-V-Q-V-A-K-F-I-N-C-L-M-L-S-G-K-K-S-V-A-E-Q-L-F-Y-D-A-L-E-I-I-Q-K-K-T-G-N-D-P-Y-T-T-F-R-E-A-L-E-N-A-K-P-Q-V-E-V-K-S-R-R-V-G-G-V-T-Y-Q-V-P-V-E-V-R-P-E-R-R-L-A-L-G-I-R-W-L-I-R-Y-S-R-D-R-N-E-K-G-M-A-A-K-L-A-A-E-F-I-E-A-Q-K-G-T-G-S-A-I-K-K-K-E-D-I-R-K-M-A-E-A-N-K-A-F-S-H-Y-R-W"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-K-I-S-V-G-N-D-I-V-E-N-S-R-I-R-D-L-L-E-K-H-G-D-R-F-L-K-R-V-F-S-E-S-E-R-E-Y-C-S-N-R-K-D-P-I-P-H-L-S-G-R-F-C-V-K-E-A-F-I-K-A-I-E-P-G-D-H-V-I-L-D-M-R-E-I-E-L-F-G-K-E-F-G-K-K-E-L-V-L-H-G-K-S-K-E-L-F-L-T-K-G-Y-S-G-C-S-V-S-I-S-H-A-E-N-Y-S-T-A-V-V-V-L-Y-K-E"} +{"text": "### FUNCTION Associates with the EF-TuGDP complex and induces the exchange of GDP to GTP It remains bound to the aminoacyl-tRNAEF-TuGTP complex up to the GTP hydrolysis stage on the ribosome ### SEQUENCE -M-A-A-V-T-T-D-L-I-R-E-L-R-E-R-T-S-A-G-M-M-D-C-K-K-A-L-E-E-N-N-A-D-I-E-K-A-I-T-W-L-R-E-K-G-I-A-K-A-A-K-K-A-G-R-E-T-K-E-G-R-V-V-S-Y-I-H-G-N-G-K-I-G-V-L-V-E-L-N-S-E-T-D-F-V-S-K-N-E-D-F-E-A-L-G-K-E-I-C-M-Q-I-A-A-M-N-P-L-Y-L-N-E-E-S-I-P-A-A-D-L-E-K-E-K-T-I-M-R-S-Q-L-E-A-E-G-K-K-A-D-Q-I-E-K-I-L-P-G-K-I-K-K-Y-V-S-E-V-C-L-V-N-Q-A-F-F-K-D-D-S-K-T-I-D-D-L-V-K-E-A-I-A-K-F-G-E-N-I-T-I-A-R-F-I-R-F-Q-V-G-G-L"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-S-D-A-I-I-S-G-M-K-T-K-M-D-K-T-I-D-L-V-K-K-D-F-G-T-I-R-T-G-R-A-N-P-S-L-V-E-D-I-R-V-D-Y-Y-G-N-Q-T-P-I-N-Q-L-G-N-I-S-V-P-E-P-R-M-L-V-I-S-P-Y-D-K-G-I-M-K-D-I-E-K-A-I-Q-T-S-G-L-G-L-Q-P-T-N-D-G-V-V-I-R-I-V-I-P-E-L-T-G-E-R-R-K-E-L-A-K-V-V-K-S-K-S-E-E-K-K-V-A-I-R-N-I-R-R-D-A-M-E-D-L-K-K-H-T-E-G-M-S-Q-D-E-I-K-S-V-Q-D-Q-I-Q-K-I-T-D-S-Y-I-D-K-I-S-A-L-T-A-E-K-E-K-E-I-T-T-I"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-K-H-W-R-L-V-S-Y-D-I-R-E-P-K-R-L-R-R-V-A-K-I-M-E-G-F-G-E-R-I-Q-Y-S-V-F-R-I-Y-S-T-D-K-E-L-E-K-L-R-W-K-L-A-K-V-T-E-E-E-D-N-I-F-Y-L-T-L-C-T-K-C-A-S-G-A-H-T-Q-E-K-K-S-A-W-P-E-A-P-K-T-L-K-I-L"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-I-F-L-N-I-I-S-I-S-I-R-L-L-L-I-L-T-L-I-T-G-I-L-Y-P-I-V-T-T-G-F-A-E-R-F-F-P-F-R-S-S-G-S-R-V-V-I-Q-G-K-I-V-G-S-E-L-I-A-Q-K-F-I-K-D-E-Y-F-W-P-R-P-S-A-M-D-Y-A-A-G-A-S-N-A-S-V-T-N-V-F-L-K-A-K-V-E-E-R-K-K-F-L-L-E-K-H-S-E-Q-T-Q-V-P-P-D-L-L-F-A-S-G-S-G-L-D-P-H-I-S-P-D-S-A-L-F-Q-I-N-R-V-A-K-S-R-K-L-T-E-G-Q-I-L-R-L-K-N-I-V-E-E-S-V-E-K-G-Y-I-G-E-N-R-I-N-V-L-L-L-N-L-K-L-D-S-E-F-G-I-I-L-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-V-L-L-A-A-K-G-L-S-L-L-D-V-N-P-G-L-V-V-W-T-L-V-T-F-L-V-V-V-L-V-L-K-K-F-A-W-D-V-I-L-K-A-L-D-E-R-A-E-T-V-Q-N-D-I-K-K-A-S-E-L-R-L-E-A-E-A-L-L-K-D-Y-E-A-R-L-N-S-A-K-D-E-A-N-A-I-V-A-E-A-K-S-D-A-L-K-L-K-N-K-L-L-E-E-T-N-G-E-V-K-A-Q-K-D-Q-A-V-K-E-I-E-L-A-K-A-K-A-L-G-Q-L-Q-A-Q-I-V-E-M-T-I-T-V-A-A-K-V-L-E-K-Q-L-K-S-E-D-Y-K-A-F-I-E-T-E-L-D-K-L-G-K-L-S-A"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-I-L-E-P-D-T-V-I-D-L-F-L-Q-P-G-G-F-Y-W-G-K-G-N-I-R-I-R-T-L-L-G-S-C-V-S-I-C-F-W-H-P-S-L-L-Y-G-G-M-A-H-V-M-L-P-F-R-P-S-S-I-H-S-D-D-S-L-N-A-K-Y-A-E-D-A-F-Q-L-F-F-E-K-L-E-G-F-K-K-Q-Y-Q-I-K-L-F-G-G-A-S-M-F-S-T-E-E-E-K-L-L-E-L-K-S-V-R-D-I-G-M-K-N-I-L-S-I-K-E-H-L-I-R-N-Q-L-L-I-S-S-E-D-L-G-G-F-S-H-R-R-I-F-F-S-L-W-D-G-E-I-Y-V-E-R-P-E-H-T"} +{"text": "### FUNCTION A probable RNA chaperone Forms a complex with KhpB which binds to cellular RNA and controls its expression Plays a role in peptidoglycan homeostasis and cell length regulation ### SEQUENCE -M-E-E-L-L-K-Y-I-V-A-S-L-V-E-F-P-E-E-I-V-I-R-E-I-E-G-E-E-Q-N-I-I-E-L-R-V-S-P-K-D-V-G-K-V-I-G-K-N-G-R-I-A-K-S-L-R-A-I-L-T-A-A-S-V-K-A-G-K-N-F-S-L-E-I-I-D"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-K-E-W-I-S-L-G-Q-L-G-K-P-F-G-I-K-G-W-L-R-L-N-V-R-E-T-V-L-C-E-L-K-T-P-I-S-L-K-L-S-K-P-D-F-H-F-P-E-K-E-I-T-L-L-E-I-R-P-H-G-G-K-F-I-V-R-F-E-G-V-T-T-P-E-E-A-A-K-W-I-G-G-F-L-F-L-P-Q-K-L-L-P-K-I-E-T-K-N-E-F-Y-I-T-D-L-I-G-L-Q-A-I-D-E-S-G-K-K-L-D-W-K-L-K-D-V-Q-D-N-P-A-H-P-I-L-V-F-V-K-E-N-G-E-E-I-L-I-P-F-L-Q-V-F-V-G-D-L-D-L-E-K-N-T-I-V-L-I-Q-P-E-I-W-N-E-I"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-Q-L-L-R-E-V-L-T-P-D-A-E-R-T-Q-N-F-T-V-G-D-T-V-K-V-H-Y-K-I-V-E-S-G-K-E-R-V-Q-I-Y-E-G-V-V-I-S-V-A-N-E-A-N-G-K-T-F-T-V-R-R-V-S-Y-D-V-G-V-E-R-I-F-P-L-F-S-P-R-I-A-K-I-E-L-I-R-K-G-K-V-R-R-A-K-L-Y-Y-L-R-N-L-A-G-K-A-A-R-I-K-E-L-K-G-G-K-A-L-V-S-E-D-R-K-R-Q-Q-A-A-A-A-T-K-S-T-T-T-E"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-V-E-T-K-S-K-I-S-F-E-D-A-L-M-E-L-E-Q-I-A-E-K-L-E-R-Q-D-F-S-L-E-E-S-L-K-A-Y-E-R-G-M-E-L-K-K-I-C-Q-G-I-L-D-T-A-E-G-K-I-E-A-L-T-K-D-E-S-K-K-T-N-K-T-G-F-R-G-E-S-K-T-T-E-T-K-N-N-T-A-Q-E-E-D-L-F"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-A-N-L-K-L-L-L-V-G-I-G-N-P-G-Q-K-Y-V-H-N-R-H-N-I-G-F-V-I-L-D-S-L-L-D-S-S-S-V-S-Y-Q-T-N-S-K-Y-S-L-A-R-T-D-E-D-G-V-T-I-F-Y-L-K-P-L-E-F-M-N-L-S-G-K-S-V-A-E-I-A-K-K-N-G-I-S-P-E-N-I-L-I-I-H-D-E-I-D-F-E-F-G-K-L-K-L-K-G-G-G-G-H-A-G-H-N-G-L-R-N-I-V-E-K-L-G-T-N-T-F-F-R-L-R-F-G-V-G-K-P-S-I-T-S-E-V-P-D-Y-V-L-S-N-F-L-P-N-E-K-E-K-I-P-E-L-V-K-V-S-L-Q-K-I-S-D-W-I-R-E-R-K-N-G-F-Q-K-L-S-D-N-Q"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-D-I-F-R-F-D-T-E-E-Q-T-L-T-K-E-K-I-K-L-K-K-P-S-K-Y-R-V-I-I-L-N-D-D-F-T-P-M-E-F-V-V-W-I-L-Q-M-V-F-H-R-S-R-A-E-S-Q-Q-I-M-L-K-A-H-I-T-G-K-A-L-C-G-V-Y-S-H-D-V-A-R-T-K-V-A-Q-V-Q-Q-L-A-E-Q-H-G-Y-P-L-H-C-T-M-E-V-E-E-G-E-E-E-S"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-F-A-P-L-A-V-F-G-S-L-G-W-T-E-I-L-L-I-L-F-I-A-L-L-L-F-G-G-K-R-L-P-S-L-A-K-D-L-G-D-G-I-R-S-F-R-K-S-L-T-G-E-S-D-D-S-S-Q-Q-I-S-Q-E-Q-E-R-S-V-P-K-E-E-T-K-T-S-K-S-K-K-S-K-S-A"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-N-C-K-I-L-F-R-K-E-L-N-D-S-E-C-E-L-S-L-L-L-V-G-D-S-D-M-K-E-I-N-R-L-R-R-G-K-D-K-T-T-D-V-L-S-F-P-L-E-F-D-F-S-P-L-Q-K-I-L-P-K-N-T-S-S-D-Q-K-M-F-P-P-I-A-L-G-E-I-V-I-S-I-D-T-L-Q-K-Q-A-K-E-I-G-H-S-E-K-D-E-F-Y-R-L-L-V-H-G-F-L-H-L-L-G-Y-D-H-E-R-G-D-K-E-E-H-I-M-K-L-K-E-D-E-C-L-E-I-L-Q-G-L"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-V-I-L-Q-K-D-V-I-N-L-G-D-A-G-D-L-K-E-V-A-D-G-Y-A-R-N-F-L-F-P-K-R-L-A-V-R-A-N-E-G-N-T-K-A-A-L-H-Q-K-K-L-G-E-L-K-R-E-K-R-K-K-A-M-E-D-V-G-G-N-L-N-G-K-E-Y-E-I-L-V-K-T-G-G-G-E-K-L-F-G-A-V-T-P-I-D-V-A-S-I-L-K-K-N-G-F-E-L-D-K-R-K-I-E-I-A-E-P-I-R-N-L-G-S-Y-K-I-K-I-R-L-A-E-G-I-Q-P-T-I-T-L-H-V-K-K-E-E-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-E-G-K-P-Q-R-K-Q-N-K-Y-K-K-K-V-C-R-F-T-A-D-P-E-L-A-K-Q-I-N-Y-K-N-I-E-L-L-E-R-F-I-T-N-R-G-K-I-I-P-R-R-I-T-G-T-S-A-R-Y-Q-R-V-L-A-R-E-I-R-K-A-R-S-I-G-L-L-P-Y-K-V-N"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-N-Y-E-L-T-T-I-T-R-V-S-S-R-E-V-A-K-S-E-I-Q-E-T-L-K-K-H-S-V-S-V-T-A-E-E-D-W-G-Q-R-K-L-W-H-P-I-K-H-E-E-Q-G-I-F-H-H-Y-K-C-S-A-D-P-N-A-I-E-K-V-E-K-E-F-L-I-N-Q-N-I-L-R-S-M-V-V-R-L-H-G"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-S-A-K-N-N-I-Q-D-Q-L-L-N-T-A-R-K-D-K-L-D-L-T-I-Y-L-L-N-G-V-P-L-K-G-K-V-V-S-F-D-N-F-T-I-V-L-E-Q-E-N-K-Q-S-L-V-Y-K-H-A-I-S-T-I-I-P-A-K-I-I-K-L-Y-T-E-E-A-K-D-N-K-D-A-A-Q-G"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-A-V-N-G-T-I-H-K-N-R-R-R-R-I-L-K-D-A-K-G-F-R-G-A-R-S-K-L-Y-R-T-A-K-S-A-V-M-K-A-G-Q-W-A-Y-R-D-R-R-A-K-K-R-D-F-R-K-L-W-I-I-R-I-N-A-A-A-R-E-N-G-L-S-Y-S-V-F-M-N-S-L-K-K-L-G-I-H-M-D-R-K-S-L-A-E-L-A-F-N-D-R-E-V-F-N-S-L-V-E-K-I-K-V-A-G"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-Q-R-K-P-S-Q-K-S-A-T-D-K-L-F-N-H-R-V-N-E-K-I-T-G-V-S-R-V-R-L-V-S-D-D-G-V-A-I-V-S-F-E-E-A-L-R-K-A-K-E-E-N-L-D-L-V-E-V-S-A-D-Q-E-L-H-V-C-K-I-I-D-Y-G-K-Y-K-F-E-L-L-K-K-S-K-E-A-K-K-K-Q-H-V-I-N-V-K-E-I-K-I-R-P-R-I-E-S-H-D-Y-E-I-K-K-K-H-A-Q-E-F-L-G-K-G-D-K-V-K-V-S-L-R-F-R-G-R-E-M-M-H-S-D-L-G-M-K-V-V-Y-R-M-I-E-D-L-K-E-H-G-T-A-E-R-D-P-I-Q-D-G-K-Q-I-V-V-I-I-N-P-K"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-I-F-V-Q-K-L-R-P-N-A-E-L-P-L-L-Q-T-K-Q-A-A-G-Y-D-I-H-A-C-L-D-S-K-L-V-L-E-P-G-N-V-G-L-V-P-T-G-L-S-F-A-I-P-Q-E-F-H-F-E-I-R-P-R-S-G-F-S-T-K-N-R-I-L-I-P-N-S-P-G-T-I-D-S-D-Y-R-G-E-L-M-I-P-L-L-N-L-G-D-S-S-F-I-I-E-H-G-M-R-I-A-Q-L-L-I-R-K-T-W-Y-A-D-W-E-L-V-S-E-F-A-D-R-T-E-R-G-A-N-G-F-G-S-T-G-H"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-T-E-I-H-P-N-Y-K-A-A-K-I-S-C-A-S-C-G-T-V-Y-E-T-R-T-S-I-G-D-I-N-I-E-I-C-S-A-C-H-P-F-F-T-G-K-S-K-L-V-D-T-T-G-R-V-D-K-F-K-K-K-Y-K-M-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-I-A-T-E-Q-K-K-Q-I-I-S-N-F-A-R-K-A-G-D-T-G-S-T-E-V-Q-I-A-L-I-D-A-R-I-K-E-L-N-E-H-F-K-T-H-K-K-D-F-H-S-K-T-G-L-L-R-L-V-G-K-R-K-K-L-L-D-Y-L-K-R-T-E-L-E-R-Y-K-K-L-I-E-T-L-G-L-R-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-N-P-I-R-R-R-K-I-E-A-E-A-V-R-T-V-A-M-M-I-L-S-G-K-V-K-D-P-R-V-H-M-V-S-V-H-R-A-E-I-S-E-D-G-K-N-M-K-V-F-V-T-A-I-C-T-D-K-K-K-I-K-V-L-S-G-L-N-S-A-S-G-L-F-Q-A-T-L-S-G-K-L-G-L-R-I-T-P-R-M-H-F-L-W-D-E-E-Y-I-Q-S-L-D-E-S-L-R-L-T-R-K-P-T-N-T-D"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-V-S-S-E-E-I-S-G-I-L-D-G-V-L-S-L-P-V-K-L-Y-S-L-K-V-N-Q-R-P-N-H-S-L-I-E-V-V-L-D-N-L-E-H-P-Y-G-S-V-S-L-L-E-C-E-Q-V-S-R-K-L-K-E-E-L-E-R-I-S-P-D-L-D-Y-T-L-K-V-S-S-A-G-A-E-R-K-L-N-L-P-G-D-L-D-R-F-R-G-I-P-I-R-L-V-F-R-S-E-E-S-E-K-E-Q-E-G-I-F-R-V-V-N-R-D-G-D-Q-I-V-L-E-K-F-Q-K-G-K-K-S-V-V-K-K-Q-T-T-L-N-L-K-D-I-L-K-G-N-L-Y-V-N-I"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-K-E-V-S-V-P-A-I-K-R-I-V-L-I-A-H-D-N-R-K-E-D-L-V-N-W-V-K-T-H-R-E-I-L-S-K-H-Q-L-Y-G-T-G-T-T-G-K-L-I-S-E-E-T-E-L-P-V-Y-R-F-L-S-G-P-L-G-G-D-Q-Q-I-G-A-K-I-A-E-G-D-L-D-I-V-I-F-F-W-D-P-L-T-A-Q-P-H-D-P-D-V-K-A-L-L-R-I-A-V-L-Y-N-V-P-M-A-C-N-R-S-T-A-D-Y-M-I-S-S-P-Q-F-T-K-T-Y-K-K-I-L-L-S-Y-N-T-K-V-K-K-D"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-N-S-S-I-L-T-G-I-F-G-G-S-F-D-P-P-H-E-G-H-S-E-I-L-K-S-F-F-W-E-V-S-D-C-K-E-V-F-V-I-P-N-R-Q-N-P-L-K-E-E-K-I-S-L-P-E-N-I-L-E-M-L-N-L-F-V-S-E-F-S-Q-S-I-R-I-L-D-L-E-L-K-R-S-G-P-S-Y-T-I-Q-T-I-Q-E-L-K-T-I-Y-P-N-R-K-F-V-L-L-I-G-E-D-N-Y-S-N-F-H-K-W-K-D-W-E-K-I-L-T-E-V-E-T-I-F-V-F-R-R-F-S-K-E-V-P-L-N-S-H-L-N-S-L-F-E-F-K-F-L-E-N-P-L-I-P-V-T-S-T-D-L-R-K-S-F-F-Q-S-K-V-P-N-L-I-S-K-K-V-L-D-Y-I-L-K-N-K-L-Y-S-K"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-S-V-G-N-R-Q-Y-K-V-T-Q-D-Q-E-F-L-T-E-K-T-G-K-N-A-G-E-S-F-D-A-K-V-L-L-F-A-E-S-N-N-K-V-H-I-G-Q-P-E-L-K-T-A-R-V-S-L-K-V-L-E-D-V-K-G-D-K-I-H-G-Y-V-Y-K-R-R-K-N-Y-Q-K-A-W-G-H-R-Q-Q-L-Q-K-V-K-V-V-S-L-S-A-V"} +{"text": "### FUNCTION Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP ### SEQUENCE -M-S-S-R-E-I-T-I-L-K-I-Q-E-P-T-R-S-I-A-S-L-T-R-I-M-E-E-E-L-S-Q-Y-R-K-T-L-P-K-G-F-R-E-E-V-D-C-D-E-D-T-V-L-F-L-H-V-D-F-L-P-L-D-F-Q-K-T-T-E-L-L-L-T-G-K-K-N-L-V-P-V-V-A-I-D-L-Q-G-Q-I-L-M-Q-A-F-G-N-E-E-S-Q-T-L-S-L-K-T-G-Y-A-H-Y-F-S-R-S-R-N-Q-L-W-K-K-G-D-T-S-G-H-T-Q-K-I-L-Q-I-L-S-P-T-D-R-S-F-L-V-Y-Q-V-E-Q-E-V-A-A-C-H-E-G-Y-Y-S-C-F-F-R-E-R-M-E-G-V-T-W-K-L-L-P-V-P-R-N-F-L-P-E-K-S"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-A-R-R-T-S-R-E-I-A-V-M-A-L-Y-Q-L-E-L-T-Q-P-P-L-K-E-V-L-K-F-K-W-Y-D-K-K-T-E-P-E-E-R-D-F-A-V-S-I-V-N-G-V-V-K-N-Q-E-Q-I-D-T-L-I-K-K-Y-S-K-N-W-D-F-S-R-I-S-I-V-N-K-A-I-L-R-L-S-I-Y-A-L-L-Y-T-W-E-V-P-K-N-V-T-I-D-E-A-V-E-L-T-K-E-F-E-S-E-E-S-A-R-F-V-N-G-V-L-D-A-I-L-K-N-E-I-K-S-D-G"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-I-Q-E-L-K-A-D-L-N-G-K-G-Q-K-H-C-V-I-V-S-R-F-N-E-F-I-T-E-S-L-L-K-G-A-L-E-S-F-R-M-H-G-V-E-D-V-T-V-V-R-V-P-G-A-Y-E-M-P-M-V-V-S-K-A-A-A-S-K-K-Y-D-S-I-V-C-L-G-A-V-I-R-G-A-T-A-H-F-D-L-V-A-G-E-S-A-K-I-G-S-I-G-V-Q-H-S-I-P-V-I-F-G-V-L-T-T-D-T-I-E-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-A-E-A-A-A-T-A-V-E-M-V-N-L-L-S-L-L"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-E-T-Q-A-P-T-G-Y-L-F-S-E-K-H-E-W-V-K-V-E-G-D-M-A-L-I-G-I-S-D-F-A-Q-S-A-L-G-D-I-V-F-V-D-L-P-K-T-G-K-N-I-K-Q-F-E-T-F-G-T-I-E-S-V-K-A-A-E-D-L-Y-A-P-I-G-G-E-V-I-E-S-N-S-A-L-S-K-N-P-G-D-V-N-S-K-P-F-D-S-W-M-I-K-V-K-G-F-S-T-S-E-L-D-K-L-L-T-P-E-K-Y-K-A-L-V-A-G-L-E"} +{"text": "### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription The complex also regulates trp repressor biosynthesis by binding to its regulatory region ### SEQUENCE -M-A-Q-Q-S-P-Y-S-A-A-M-A-E-Q-R-H-Q-E-W-L-R-F-V-D-L-L-K-N-A-Y-Q-N-D-L-H-L-P-L-L-N-L-M-L-T-P-D-E-R-E-A-L-G-T-R-V-R-I-V-E-E-L-L-R-G-E-M-S-Q-R-E-L-K-N-E-L-G-A-G-I-A-T-I-T-R-G-S-N-S-L-K-A-A-P-V-E-L-R-Q-W-L-E-D-V-L-L-K-S-D"} +{"text": "### FUNCTION This protein is required for primosome-dependent normal DNA replication ### SEQUENCE -M-S-S-R-V-L-T-P-D-V-V-G-I-D-A-L-V-H-D-H-Q-T-V-L-A-K-A-E-G-G-V-V-A-V-F-D-N-N-A-P-A-F-Y-A-V-T-P-A-R-L-A-E-L-L-A-L-E-E-K-L-A-R-P-G-S-D-V-A-L-D-D-Q-L-Y-Q-E-P-Q-T-A-P-V-A-V-P-M-G-K-F-A-M-Y-P-D-W-Q-P-D-A-D-F-I-R-L-A-A-L-W-G-V-A-L-R-E-P-V-T-A-E-E-L-A-S-F-I-A-Y-W-Q-A-E-G-K-V-F-H-H-V-Q-W-Q-Q-K-L-A-R-S-L-Q-I-G-R-A-S-N-G-G-L-P-K-R-D-V-N-T-V-S-E-P-D-S-Q-I-P-P-G-F-R-G"} +{"text": "### FUNCTION Involved in the degradation and recycling of damaged RNA It is itself a target for degradation by the ATP-dependent protease Lon ### SEQUENCE -M-T-D-T-H-S-I-A-Q-P-F-E-A-E-V-S-P-A-N-N-R-Q-L-T-V-S-Y-A-S-R-Y-P-D-Y-S-R-I-P-A-I-T-L-K-G-Q-W-L-E-A-A-G-F-A-T-G-T-V-V-D-V-K-V-M-E-G-C-I-V-L-T-A-Q-P-P-A-A-A-E-S-E-L-M-Q-S-L-R-Q-V-C-K-L-S-A-R-K-Q-R-Q-V-Q-E-F-I-G-V-I-A-G-K-Q-K-V-A"} +{"text": "### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway ### SEQUENCE -M-M-R-Q-S-V-Q-T-V-L-P-E-S-T-G-N-N-T-L-S-L-R-D-S-V-C-R-D-L-F-Q-L-F-S-S-P-H-S-P-L-P-I-L-L-V-S-G-M-P-E-W-Q-G-H-N-Q-S-D-K-L-L-Q-S-W-Y-C-R-Q-L-R-S-A-L-L-F-H-E-P-R-I-A-A-L-Q-V-N-L-K-E-A-Y-C-H-E-L-A-I-S-L-E-M-M-L-Y-H-D-D-E-P-L-T-F-D-L-V-W-Q-K-G-S-W-H-R-T-M-P-Q"} +{"text": "### FUNCTION The phosphoenolpyruvate-dependent sugar phosphotransferase system , a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane The enzyme II UlaABC PTS system is involved in ascorbate transport ### SEQUENCE -M-K-L-R-D-S-L-A-E-N-K-S-I-R-L-Q-A-E-A-N-T-W-Q-E-A-V-K-I-G-V-D-L-L-V-A-A-D-V-V-E-P-R-Y-Y-Q-A-I-L-D-G-V-E-Q-F-G-P-Y-F-V-I-A-P-G-L-A-M-P-H-G-R-P-E-E-G-V-K-K-T-G-F-S-L-V-T-L-K-K-P-L-E-F-N-H-E-D-N-D-P-V-D-I-L-I-T-M-A-A-V-D-A-N-T-H-Q-E-V-G-I-M-Q-I-V-N-L-F-E-D-E-E-N-F-D-R-L-R-A-C-R-T-E-Q-E-V-L-D-L-I-D-R-T-N-A-A-A"} +{"text": "### FUNCTION Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion ### SEQUENCE -M-I-N-P-N-P-K-R-S-D-E-P-V-F-W-G-L-F-G-A-G-G-M-W-S-A-I-I-A-P-V-M-I-L-L-V-G-I-L-L-P-I-G-L-F-P-G-D-A-L-S-Y-E-R-V-L-A-F-A-Q-S-F-I-G-R-V-F-L-F-L-M-I-V-L-P-L-W-C-G-L-H-R-M-H-H-A-M-H-D-L-K-I-H-V-P-A-G-K-W-V-F-Y-G-L-A-A-I-L-T-V-V-T-L-I-G-V-V-T-I"} +{"text": "### FUNCTION Guanidinium ion exporter Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons ### SEQUENCE -M-S-W-I-I-L-V-I-A-G-L-L-E-V-V-W-A-V-G-L-K-Y-T-H-G-F-S-R-L-T-P-S-V-I-T-V-T-A-M-I-V-S-L-A-L-L-A-W-A-M-K-S-L-P-V-G-T-A-Y-A-V-W-T-G-I-G-A-V-G-A-A-I-T-G-I-V-L-L-G-E-S-A-N-P-M-R-L-A-S-L-A-L-I-V-L-G-I-I-G-L-K-L-S-T-H"} +{"text": "### FUNCTION Involved in resistance toward heavy metals ### SEQUENCE -M-L-D-E-K-S-S-N-T-T-S-V-V-V-L-C-T-A-P-D-E-A-T-A-Q-D-L-A-A-K-V-L-A-E-K-L-A-A-C-A-T-L-I-P-G-A-T-S-L-Y-Y-W-E-G-K-L-E-Q-E-Y-E-V-Q-M-I-L-K-T-T-V-S-H-Q-Q-A-L-L-E-C-L-K-S-H-H-P-Y-Q-T-P-E-L-L-V-L-P-V-T-H-G-D-T-D-Y-L-S-W-L-N-A-S-L-R"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-S-H-P-A-L-T-Q-L-R-A-L-R-Y-F-T-E-I-P-A-L-E-P-Q-L-L-D-W-L-L-L-E-D-S-M-T-K-R-F-E-Q-Q-G-K-T-V-S-V-T-M-I-R-E-G-F-V-E-Q-N-E-I-P-E-E-L-P-L-L-P-K-E-S-R-Y-W-L-R-E-I-L-L-C-A-D-G-E-P-W-L-A-G-R-T-V-V-P-V-S-T-L-S-G-P-E-L-A-L-Q-K-L-G-K-T-P-L-G-R-Y-L-F-T-S-S-T-L-T-R-D-F-I-E-I-G-R-D-A-G-L-W-G-R-R-S-R-L-R-L-S-G-K-P-L-L-L-T-E-L-F-L-P-A-S-P-L-Y"} +{"text": "### FUNCTION Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase ### SEQUENCE -M-L-N-Q-L-D-N-L-T-E-R-V-R-G-S-N-K-L-V-D-R-W-L-H-V-R-K-H-L-L-V-A-Y-Y-N-L-V-G-I-K-P-G-K-E-S-Y-M-R-L-N-E-K-A-L-D-D-F-C-Q-S-L-V-D-Y-L-S-A-G-H-F-S-I-Y-E-R-I-L-H-K-L-E-G-N-G-Q-L-A-R-A-A-K-I-W-P-Q-L-E-A-N-T-Q-Q-I-M-D-D-Y-D-S-S-L-E-T-A-I-D-H-D-N-Y-L-E-F-Q-Q-V-L-S-D-I-G-E-A-L-E-A-R-F-V-L-E-D-K-L-I-L-L-V-L-D-A-A-R-V-K-H-P-A"} +{"text": "### FUNCTION A GTPase-activating protein that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-K-P-S-S-S-N-S-R-S-K-G-H-A-K-A-R-R-K-T-R-E-E-L-D-Q-E-A-R-D-R-K-R-Q-K-K-R-R-G-H-A-P-G-S-R-A-A-G-G-N-T-T-S-G-S-K-G-Q-N-A-P-K-D-P-R-I-G-S-K-T-P-I-P-L-G-V-A-E-K-V-T-K-Q-H-K-P-K-S-E-K-P-M-L-S-P-Q-A-E-L-E-L-L-E-T-D-E-R-L-D-A-L-L-E-R-L-E-A-G-E-T-L-S-A-E-E-Q-S-W-V-D-A-K-L-D-R-I-D-E-L-M-Q-K-L-G-L-S-Y-D-D-D-E-E-E-E-E-D-E-K-Q-E-D-M-M-R-L-L-R-G-N"} +{"text": "### FUNCTION Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites Termination signals are bypassed, which allows complete synthesis of long RNA chains Contributes to intestinal colonization via regulation of the lipopolysaccharide core synthesis ### SEQUENCE -M-Q-S-W-Y-L-L-Y-C-K-R-G-Q-L-Q-R-A-Q-E-H-L-E-R-Q-A-V-N-C-L-A-P-M-I-T-L-E-K-I-V-R-G-K-R-T-A-V-S-E-P-L-F-P-N-Y-L-F-V-E-F-D-P-E-V-I-H-T-T-T-I-N-A-T-R-G-V-S-H-F-V-R-F-G-A-S-P-A-I-V-P-S-A-V-I-H-Q-L-S-V-Y-K-P-K-D-I-V-D-P-S-T-P-Y-P-G-D-K-V-I-I-T-E-G-A-F-E-G-F-Q-A-I-F-T-E-P-D-G-E-A-R-S-M-L-L-L-N-L-I-N-K-E-I-K-H-S-V-K-N-T-E-F-R-K-L"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-S-E-L-L-L-V-F-I-I-G-L-V-V-L-G-P-Q-R-L-P-V-A-V-K-T-V-A-G-W-I-R-A-L-R-S-L-A-T-T-V-Q-N-E-L-T-Q-E-L-K-L-Q-E-F-Q-D-S-L-K-K-V-E-K-A-S-L-T-N-L-T-P-E-L-K-A-S-M-D-E-L-R-Q-A-A-E-S-M-K-R-S-Y-V-A-N-D-P-E-K-A-S-D-E-A-H-T-I-H-N-P-V-V-K-D-N-E-T-A-H-E-G-V-T-P-A-A-A-Q-T-Q-A-S-S-P-E-Q-K-P-E-T-T-P-E-P-V-V-K-P-A-A-D-A-E-P-K-T-A-A-P-S-P-S-S-S-D-K-P"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-D-S-E-F-H-R-L-A-D-Q-L-W-L-T-I-E-E-H-L-D-D-W-G-G-D-S-D-I-D-C-E-I-N-G-G-V-L-T-I-T-F-E-N-G-S-K-I-I-I-N-R-Q-E-P-L-H-Q-V-W-L-A-T-K-Q-G-G-Y-H-F-D-L-K-G-D-E-W-I-C-D-R-S-G-E-T-F-W-D-L-L-E-Q-A-A-T-Q-Q-A-G-E-T-V-S-F-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-E-F-I-T-V-A-R-P-Y-A-K-A-A-F-D-F-A-V-E-H-Q-S-V-E-R-W-Q-D-M-L-A-F-A-A-E-V-T-K-N-E-Q-M-A-E-L-L-S-G-A-L-A-P-E-T-L-A-E-S-F-I-A-V-C-G-E-Q-L-D-E-N-G-Q-N-L-I-R-V-M-A-E-N-G-R-L-K-A-L-P-D-V-L-E-Q-F-I-H-L-R-A-V-S-E-A-T-A-E-V-D-V-I-S-A-A-A-L-S-E-Q-Q-L-A-K-I-S-A-A-M-E-K-R-L-S-R-K-V-K-L-N-C-K-I-D-K-S-V-M-A-G-V-I-I-R-A-G-D-M-V-I-D-G-S-V-R-G-R-L-E-R-L-A-D-V-L-Q-S"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-V-K-L-A-F-P-R-E-L-R-L-L-T-P-S-Q-F-T-F-V-F-Q-Q-P-Q-R-A-G-T-P-Q-I-T-I-L-G-R-L-N-S-L-G-H-P-R-I-G-L-T-V-A-K-K-N-V-R-R-A-H-E-R-N-R-I-K-R-L-T-R-E-S-F-R-L-R-Q-H-E-L-P-A-M-D-F-V-V-V-A-K-K-G-V-A-D-L-D-N-R-A-L-S-E-A-L-E-K-L-W-R-R-H-C-R-L-A-R-G-P"} +{"text": "### FUNCTION May act as a transcriptional regulator of dctA ### SEQUENCE -M-F-L-I-I-T-R-D-T-M-F-F-T-A-M-K-N-I-L-S-K-G-N-V-V-H-I-Q-N-E-E-E-I-D-V-M-L-H-Q-N-A-F-V-I-I-D-T-L-M-N-N-V-F-H-S-N-F-L-T-Q-I-E-R-L-K-P-V-H-V-I-I-F-S-P-F-N-I-K-R-C-L-G-K-V-P-V-T-F-V-P-R-T-I-A-I-I-D-F-V-A-L-I-N-G-S-Y-C-S-V-P-E-A-D-V-S-L-S-R-K-Q-H-Q-V-L-S-C-I-A-N-Q-M-T-T-E-D-I-L-E-K-L-K-I-S-L-K-T-F-Y-C-H-K-H-N-I-M-M-I-L-N-L-K-R-I-N-E-L-V-R-H-Q-H-I-N-Y-L-V"} +{"text": "### FUNCTION May function as a transcriptional regulator that controls feoABC expression ### SEQUENCE -M-A-S-L-I-Q-V-R-D-L-L-A-L-R-G-R-M-E-A-A-Q-I-S-Q-T-L-N-T-P-Q-P-M-I-N-A-M-L-K-Q-L-E-S-M-G-K-A-V-R-I-Q-E-E-P-D-G-C-L-S-G-S-C-K-S-C-P-E-G-K-A-C-L-H-E-W-W-A-L-R"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-R-F-A-I-V-V-T-G-P-A-Y-G-T-Q-Q-A-S-S-A-F-Q-F-A-Q-A-L-I-A-E-G-H-E-L-S-S-V-F-F-Y-R-E-G-V-Y-N-A-N-Q-L-T-S-P-A-S-D-E-F-D-L-V-R-S-W-Q-Q-L-N-M-Q-H-G-V-A-L-N-I-C-V-A-A-A-L-R-R-G-V-V-D-E-T-E-A-G-R-L-G-L-A-S-S-N-L-Q-T-G-F-T-L-S-G-L-G-A-L-A-E-A-S-L-T-C-D-R-V-V-Q-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-K-R-I-A-F-V-F-S-T-V-P-H-G-T-A-A-G-R-E-G-L-D-A-L-L-A-T-S-A-L-T-D-D-L-A-V-F-F-I-A-D-G-V-F-Q-L-L-P-G-Q-K-P-D-A-V-L-A-R-D-Y-I-A-T-F-K-L-L-G-L-Y-D-I-E-Q-C-W-V-C-A-A-S-L-R-E-R-G-L-D-P-Q-T-P-F-V-V-E-A-T-P-L-E-A-D-A-L-R-R-E-L-A-N-Y-D-V-I-L-R-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-L-H-T-L-H-R-S-P-W-L-T-D-F-A-A-L-L-R-L-L-S-E-G-D-E-L-L-L-L-Q-D-G-V-T-A-A-V-D-G-N-R-Y-L-E-S-L-R-N-A-P-I-K-V-Y-A-L-N-E-D-L-I-A-R-G-L-T-G-R-I-S-N-D-I-I-P-I-D-Y-T-D-F-V-R-L-T-V-K-H-S-S-Q-M-A-W"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-D-D-E-V-I-V-L-T-G-K-D-K-G-K-R-G-K-V-K-N-V-L-S-S-G-K-V-I-V-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-L-N-Q-P-G-G-I-V-E-K-E-A-A-I-Q-V-S-N-V-A-I-F-N-A-T-T-G-K-A-D-R-V-G-F-R-F-E-D-G-K-K-V-R-F-F-K-S-N-S-E-T-I-K"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-I-I-K-E-F-R-E-F-A-M-R-G-N-V-V-D-L-A-V-G-V-I-I-G-A-A-F-G-K-I-V-S-S-L-V-A-D-I-I-M-P-P-L-G-L-L-I-G-G-I-D-F-K-Q-F-A-V-T-L-R-E-A-Q-G-D-I-P-A-V-V-M-H-Y-G-V-F-I-Q-N-V-F-D-F-L-I-V-A-F-A-I-F-M-A-I-K-L-I-N-K-L-N-R-K-K-E-E-P-A-A-A-T-P-A-P-T-K-E-E-V-L-L-T-E-I-R-D-L-L-K-E-Q-N-N-R-S"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-R-S-S-A-K-Q-E-E-L-V-K-A-F-K-A-L-L-K-E-E-K-F-S-S-Q-G-E-I-V-A-A-L-Q-E-Q-G-F-D-N-I-N-Q-S-K-V-S-R-M-L-T-K-F-G-A-V-R-T-R-N-A-K-M-E-M-V-Y-C-L-P-A-E-L-G-V-P-T-T-S-S-P-L-K-N-L-V-L-D-I-D-Y-N-D-A-V-V-V-I-H-T-S-P-G-A-A-Q-L-I-A-R-L-L-D-S-L-G-K-A-E-G-I-L-G-T-I-A-G-D-D-T-I-F-T-T-P-A-N-G-F-T-V-K-E-L-Y-E-A-I-L-E-L-F-D-Q-E-L"} +{"text": "### FUNCTION Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein ### SEQUENCE -M-Q-E-R-I-K-A-C-F-T-E-S-I-Q-T-Q-I-A-A-A-E-A-L-P-D-A-I-S-R-A-A-M-T-L-V-Q-S-L-L-N-G-N-K-I-L-C-C-G-N-G-T-S-A-A-N-A-Q-H-F-A-A-S-M-I-N-R-F-E-T-E-R-P-S-L-P-A-I-A-L-N-T-D-N-V-V-L-T-A-I-A-N-D-R-L-H-D-E-V-Y-A-K-Q-V-R-A-L-G-H-A-G-D-V-L-L-A-I-S-T-R-G-N-S-R-D-I-V-K-A-V-E-A-A-V-T-R-D-M-T-I-V-A-L-T-G-Y-D-G-G-E-L-A-G-L-L-G-P-Q-D-V-E-I-R-I-P-S-H-R-S-A-R-I-Q-E-M-H-M-L-T-V-N-C-L-C-D-L-I-D-N-T-L-F-P-H-Q-D-V"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-D-F-P-Q-R-V-N-G-W-A-L-Y-A-H-P-C-F-Q-E-T-Y-D-A-L-V-A-E-V-E-A-L-K-G-K-D-P-E-N-Y-Q-R-K-A-A-T-K-L-L-A-V-V-H-K-V-I-E-E-H-I-T-V-N-P-S-S-P-A-F-R-H-G-K-S-L-G-S-G-K-N-K-D-W-S-R-V-K-F-G-A-G-R-Y-R-L-F-F-R-Y-S-E-K-E-K-V-I-I-L-G-W-M-N-D-E-N-T-L-R-T-Y-G-K-K-T-D-A-Y-T-V-F-S-K-M-L-K-R-G-H-P-P-A-D-W-E-S-L-T-Q-E-T-E-E-S-H"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-L-C-Q-S-A-V-E-I-I-Q-R-Q-A-E-Q-H-D-V-K-R-V-T-A-V-W-L-E-I-G-A-L-S-C-V-E-E-S-A-V-R-F-S-F-E-I-V-C-H-G-T-V-A-Q-G-C-D-L-H-I-V-Y-K-P-A-Q-A-W-C-W-D-C-S-Q-V-V-E-I-H-Q-H-D-A-Q-C-P-I-C-H-G-E-R-L-R-V-D-T-G-D-S-L-I-V-K-S-I-E-V-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-Q-R-E-A-E-G-Q-D-F-Q-L-Y-P-G-E-L-G-K-R-I-Y-N-E-I-S-K-E-A-W-A-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-A-E-H-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-K-E-V-H-I-E-G-F-T-P-E-D-K-K"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-I-P-A-E-L-K-Y-S-K-E-H-E-W-L-R-K-E-A-D-G-T-Y-T-V-G-I-T-E-H-A-Q-E-L-L-G-D-M-V-F-V-D-L-P-E-V-G-A-T-V-S-A-G-D-D-C-A-V-A-E-S-V-K-A-A-S-D-I-Y-A-P-V-S-G-E-I-V-A-V-N-D-A-L-S-D-S-P-E-L-V-N-S-E-P-Y-A-G-G-W-I-F-K-I-K-A-S-D-E-S-E-L-E-S-L-L-D-A-T-A-Y-E-A-L-L-E-D-E"} +{"text": "### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-Q-P-N-D-I-T-F-F-Q-R-F-Q-D-D-I-L-A-G-R-K-T-I-T-I-R-D-E-S-E-S-H-F-K-T-G-D-V-L-R-V-G-R-F-E-D-D-G-Y-F-C-T-I-E-V-T-A-T-S-T-V-T-L-D-T-L-T-E-K-H-A-E-Q-E-N-M-T-L-T-E-L-K-K-V-I-A-D-I-Y-P-D-Q-T-Q-F-Y-V-I-E-F-K-C-L"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-G-K-L-T-L-L-L-L-A-I-L-V-W-L-Q-Y-S-L-W-F-G-K-N-G-I-H-D-Y-T-R-V-N-N-D-V-A-A-Q-Q-A-T-N-A-K-L-K-A-R-N-D-Q-L-F-A-E-I-D-D-L-N-G-G-Q-E-A-L-E-E-R-A-R-N-E-L-S-M-T-R-P-G-E-T-F-Y-R-L-V-P-D-A-S-K-R-A-Q-S-A-G-Q-N-N-R"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-I-T-L-C-Q-R-A-L-E-L-I-E-Q-Q-A-A-K-H-G-A-K-R-V-T-G-V-W-L-K-I-G-A-F-S-C-V-E-T-S-S-L-A-F-C-F-D-L-V-C-R-G-S-V-A-E-G-C-K-L-H-L-E-E-Q-E-A-E-C-W-C-E-T-C-Q-Q-Y-V-T-L-L-T-Q-R-V-R-R-C-P-L-C-H-G-D-M-L-Q-I-V-A-D-D-G-L-Q-I-R-R-I-E-I-D-Q-E"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-S-K-E-Q-K-T-P-E-G-Q-A-P-E-E-I-I-M-D-Q-H-E-E-I-E-A-V-E-P-E-A-S-A-E-Q-V-D-P-R-D-E-K-I-A-N-L-E-A-Q-L-A-E-A-Q-T-R-E-R-D-G-I-L-R-V-K-A-E-M-E-N-L-R-R-R-T-E-L-D-I-E-K-A-H-K-F-A-L-E-K-F-I-N-E-L-L-P-V-I-D-S-L-D-R-A-L-E-V-A-D-K-A-N-P-D-M-S-A-M-V-E-G-I-E-L-T-L-K-S-M-L-D-V-V-R-K-F-G-V-E-V-I-A-E-T-N-V-P-L-D-P-N-V-H-Q-A-I-A-M-V-E-S-D-D-V-A-P-G-N-V-L-G-I-M-Q-K-G-Y-T-L-N-G-R-T-I-R-A-A-M-V-T-V-A-K-A-K-A"} +{"text": "### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-T-G-I-Q-I-T-K-A-A-N-D-D-L-L-N-S-F-W-L-L-D-S-E-K-G-E-A-R-C-I-V-A-K-A-G-F-A-E-D-E-V-V-A-V-S-K-L-G-D-I-E-Y-R-E-V-P-V-E-V-K-P-E-V-R-V-E-G-G-Q-H-L-N-V-N-V-L-R-R-E-T-L-E-D-A-V-K-H-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-A-R-T-F-T-E-S-L"} +{"text": "### FUNCTION Exporter of O-acetylserine and cysteine ### SEQUENCE -M-T-P-T-L-L-S-A-F-W-T-Y-T-L-I-T-A-M-T-P-G-P-N-N-I-L-A-L-S-S-A-T-S-H-G-F-R-Q-S-T-R-V-L-A-G-M-S-L-G-F-L-I-V-M-L-L-C-A-G-I-S-F-S-L-A-V-I-D-P-A-A-V-H-L-L-S-W-A-G-A-A-Y-I-V-W-L-A-W-K-I-A-T-S-P-T-K-E-D-G-L-Q-T-K-P-I-S-F-W-A-S-F-A-L-Q-F-V-N-V-K-I-I-L-Y-G-V-T-A-L-S-T-F-V-L-P-Q-T-Q-A-L-S-W-V-V-G-V-S-V-L-L-A-M-I-G-T-F-G-N-V-C-W-A-L-A-G-H-L-F-Q-R-L-F-R-Q-Y-G-R-Q-L-N-I-V-L-A-L-L-L-V-Y-C-A-V-R-I-F-Y"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-L-G-L-G-T-D-I-V-E-I-A-R-I-E-A-V-I-A-R-S-G-E-R-L-A-R-R-V-L-S-D-N-E-W-E-I-W-K-T-H-H-Q-P-V-R-F-L-A-K-R-F-A-V-K-E-A-A-A-K-A-F-G-T-G-I-R-N-G-L-A-F-N-Q-F-E-V-F-N-D-E-L-G-K-P-R-L-R-L-W-G-E-A-L-K-L-A-E-K-L-G-V-V-N-M-H-V-T-L-A-D-E-R-H-Y-A-C-A-T-V-I-I-E-S"} +{"text": "### FUNCTION May function as iron donor in the assembly of iron-sulfur clusters ### SEQUENCE -M-G-L-K-W-T-D-S-R-E-I-G-E-A-L-Y-D-A-Y-P-D-I-D-P-K-T-V-R-F-T-D-M-H-Q-W-I-C-A-L-E-D-F-D-D-D-P-Q-A-S-N-E-K-I-L-E-A-I-L-L-V-W-L-D-E-A-E"} +{"text": "### FUNCTION Catalyzes the dephosphorylation of heptose of the outer membrane lipopolysaccharide core ### SEQUENCE -M-L-A-F-C-R-S-S-L-K-S-K-K-Y-F-I-I-L-L-A-L-A-A-I-A-G-L-G-T-H-A-A-W-S-S-N-G-L-P-R-I-D-N-K-T-L-A-R-L-A-Q-Q-H-P-V-V-V-L-F-R-H-A-E-R-C-D-R-S-T-N-Q-C-L-S-D-K-T-G-I-T-V-K-G-T-Q-D-A-R-E-L-G-N-A-F-S-A-D-I-P-D-F-D-L-Y-S-S-N-T-V-R-T-I-Q-S-A-T-W-F-S-A-G-K-K-L-T-V-D-K-R-F-L-Q-C-G-N-E-I-Y-S-A-I-K-D-L-Q-R-K-A-P-D-K-N-I-V-I-F-T-H-N-H-C-L-T-Y-I-A-K-D-K-R-D-A-T-F-K-P-D-Y-L-D-G-L-V-M-H-V-E-K-G-K-V-Y-L-D-G-E-F-V-N-H"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-F-T-I-N-A-E-V-R-K-E-Q-G-K-G-A-S-R-R-L-R-A-A-N-K-F-P-A-I-I-Y-G-G-K-E-A-P-L-A-V-E-L-D-H-D-K-V-M-N-M-Q-V-K-A-E-F-Y-S-E-V-L-T-I-V-V-D-G-K-E-I-K-V-K-A-Q-D-V-Q-R-H-P-Y-K-P-K-L-L-H-I-D-F-V-R-A"} +{"text": "### FUNCTION Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD As a transcriptional regulator, acts as an anti-FlhDC factor ### SEQUENCE -M-N-N-A-P-H-L-Y-F-A-W-Q-Q-L-V-E-K-S-Q-L-M-L-R-L-A-T-E-E-Q-W-D-E-L-I-A-S-E-M-A-Y-V-N-A-V-Q-E-I-A-H-L-T-E-E-V-A-P-S-T-T-M-Q-E-Q-L-R-P-M-L-H-L-I-L-D-N-E-S-K-V-K-Q-L-L-Q-I-R-M-D-E-L-A-K-L-V-G-Q-S-S-V-Q-K-S-V-L-S-A-Y-G-D-Q-G-G-F-V-L-A-P-Q-D-N-L-F"} +{"text": "### FUNCTION Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors In its active ### SEQUENCE -M-A-D-K-E-L-K-F-L-V-V-D-D-F-S-T-M-R-R-I-V-R-N-L-L-K-E-L-G-F-N-N-V-E-E-A-E-D-G-L-D-A-L-N-K-L-Q-A-G-G-Y-G-F-V-I-S-D-W-N-M-P-N-M-D-G-L-E-L-L-K-T-I-R-A-D-G-A-M-S-A-L-P-V-L-M-V-T-A-E-A-K-K-E-N-I-I-A-A-A-Q-A-G-A-S-G-Y-V-V-K-P-F-T-A-A-T-L-E-E-K-L-N-K-I-F-E-K-L-G-M"} +{"text": "### FUNCTION PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP ### SEQUENCE -M-K-K-F-R-W-V-A-L-V-V-V-V-L-A-C-L-L-L-W-A-Q-V-F-N-M-M-C-D-Q-D-V-Q-F-F-S-G-I-C-A-I-N-Q-F-I-P-W"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-N-I-T-A-T-V-L-L-A-F-G-M-S-M-D-A-F-A-A-S-I-G-K-G-A-T-L-H-K-P-K-F-S-E-A-L-R-T-G-L-I-F-G-A-V-E-T-L-T-P-L-I-G-W-G-M-G-M-L-A-S-R-F-V-L-E-W-N-H-W-I-A-F-V-L-L-I-F-L-G-G-R-M-I-I-E-G-F-R-G-A-D-D-E-D-E-E-P-R-R-R-H-G-F-W-L-L-V-T-T-A-I-A-T-S-L-D-A-M-A-V-G-V-G-L-A-F-L-Q-V-N-I-I-A-T-A-L-A-I-G-C-A-T-L-I-M-S-T-L-G-M-M-V-G-R-F-I-G-S-I-I-G-K-K-A-E-I-L-G-G-L-V-L-I-G-I-G-V-Q-I-L-W-T-H-F-H-G"} +{"text": "### FUNCTION Probably mediates the hydrolysis of some nucleoside diphosphate derivatives ### SEQUENCE -M-E-Y-R-S-L-T-L-D-D-F-L-S-R-F-Q-L-L-R-P-Q-I-N-R-E-T-L-N-H-R-Q-A-A-V-L-I-P-I-V-R-R-P-Q-P-G-L-L-L-T-Q-R-S-I-H-L-R-K-H-A-G-Q-V-A-F-P-G-G-A-V-D-D-T-D-T-S-V-I-A-A-A-L-R-E-A-E-E-E-V-A-I-P-P-S-A-V-E-V-I-G-V-L-P-P-V-D-S-V-T-G-Y-Q-V-T-P-V-V-G-I-I-P-P-D-L-P-Y-R-A-S-E-D-E-V-S-A-V-F-E-M-P-L-A-Q-A-L-H-L-G-R-Y-H-P-L-D-I-Y-R-R-G-D-S-H-R-V-W-L-S-W-Y-E-Q-Y-F-V-W-G-M-T-A-G-I-I-R-E-L-A-L-Q-I-G-V-K-P"} +{"text": "### FUNCTION Activates the cell division inhibited by chromosomal DNA over-replication ### SEQUENCE -M-K-K-P-L-R-Q-Q-N-R-Q-I-I-S-Y-V-P-R-T-E-P-A-P-P-E-H-A-I-K-M-D-S-F-R-D-V-W-M-L-R-G-K-Y-V-A-F-V-L-M-G-E-S-F-L-R-S-P-A-F-T-V-P-E-S-A-Q-R-W-A-N-Q-I-R-Q-E-N-E-V-E-E"} +{"text": "### FUNCTION Participates in cysteine desulfuration mediated by SufS Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process ### SEQUENCE -M-A-L-L-P-D-K-E-K-L-L-R-N-F-L-R-C-A-N-W-E-E-K-Y-L-Y-I-I-E-L-G-Q-R-L-P-E-L-R-D-E-D-K-S-P-Q-N-S-I-Q-G-C-Q-S-Q-V-W-I-V-M-R-Q-N-A-Q-G-I-I-E-L-Q-G-D-S-D-A-A-I-V-K-G-L-I-A-V-V-F-I-L-Y-D-Q-M-T-P-Q-D-I-V-N-F-D-V-R-P-W-F-E-K-M-A-L-T-Q-H-L-T-P-S-R-S-Q-G-L-E-A-M-I-R-A-I-R-A-K-A-A-A-L-S"} +{"text": "### FUNCTION Catalyzes the excretion of spermidine ### SEQUENCE -M-Y-I-Y-W-I-L-L-G-L-A-V-A-T-E-I-T-G-T-L-S-M-K-W-A-S-V-S-E-G-N-G-G-F-I-L-M-L-V-M-I-S-L-S-Y-I-F-L-S-F-A-V-K-K-I-A-L-G-V-A-Y-A-L-W-E-G-I-G-I-L-F-I-T-L-F-S-V-L-L-F-D-E-S-L-S-L-M-K-I-A-G-L-T-T-L-V-A-G-I-V-L-I-K-S-G-T-R-K-A-R-K-P-E-L-E-V-N-H-G-A-V"} +{"text": "### FUNCTION Catalyzes the excretion of spermidine ### SEQUENCE -M-A-Q-F-E-W-V-H-A-A-W-L-A-L-A-I-V-L-E-I-I-A-N-V-F-L-K-F-S-D-G-F-R-R-K-I-F-G-L-L-S-L-A-A-V-L-A-A-F-S-A-L-S-Q-A-V-K-G-I-D-L-S-V-A-Y-A-L-W-G-G-F-G-I-A-A-T-L-A-A-G-W-I-L-F-G-Q-R-L-N-R-K-G-W-I-G-L-V-L-L-L-A-G-M-I-M-V-K-L-A"} +{"text": "### FUNCTION Antitoxin component of a type II type II toxin-antitoxin ### SEQUENCE -M-L-W-T-Y-D-M-M-S-F-Q-K-I-Y-S-P-T-Q-L-A-N-A-M-K-L-V-R-Q-Q-N-G-W-T-Q-S-E-L-A-K-K-I-G-I-K-Q-A-T-I-S-N-F-E-N-N-P-D-N-T-S-L-T-T-F-F-K-I-L-Q-S-L-E-L-S-M-T-L-C-D-A-K-N-A-S-P-E-A-A-E-Q-Q-D-L-E-W"} +{"text": "### FUNCTION Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions ### SEQUENCE -M-H-A-T-T-V-K-N-K-I-T-Q-R-D-N-Y-K-E-I-M-S-V-I-V-V-V-L-L-L-T-L-T-L-I-A-I-F-S-A-I-D-Q-L-G-I-S-E-M-G-R-I-A-R-D-L-T-H-F-I-I-N-S-L-Q-D"} +{"text": "### FUNCTION Regulates expression of genes involved in acid-resistance and biofilm formation May be a non-specific DNA-binding protein that binds genes and/or intergenic regions via a geometric recognition ### SEQUENCE -M-L-E-D-T-T-I-H-N-A-I-S-D-K-A-L-S-S-Y-F-R-S-S-G-N-L-L-E-E-E-S-A-V-L-G-Q-A-V-T-N-L-M-L-S-G-D-N-V-N-N-K-N-I-I-L-S-L-I-H-S-L-E-T-T-S-D-I-L-K-A-D-V-I-R-K-T-L-E-I-V-L-R-Y-T-A-D-D-M"} +{"text": "### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation ### SEQUENCE -M-K-W-I-V-I-D-T-V-I-Q-P-S-C-G-I-S-F-S-V-I-W-S-K-I-K-L-I-I-W-Y-Q-S-D-A-F-L-P-P-E-S-I-F-T-L-T-H-T-G-I-M-L-N-N-K-V-L-P-V-T-I-Y-N-V-V-P-F-N-K-T-F-W-N-L-I-K-N-S-Q-E-C-P-T-N-T-D-N-V-L-N-E-C-F-N-N-R-C-T-L-Q-I-C-P-Y-G-L-K-Q-Q-S-P"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-P-K-L-I-L-A-S-T-S-P-W-R-R-A-L-L-E-K-L-Q-I-S-F-E-C-A-A-P-E-V-D-E-T-P-R-S-D-E-S-P-R-Q-L-V-L-R-L-A-Q-E-K-A-Q-S-L-A-S-C-Y-P-D-H-L-I-I-G-S-D-Q-V-C-V-L-D-G-E-I-T-G-K-P-L-T-E-E-N-A-R-L-Q-L-R-K-A-S-G-N-I-V-T-F-Y-T-G-L-A-L-F-N-S-A-N-G-H-L-Q-T-E-V-E-P-F-D-V-H-F-R-H-L-S-E-A-E-I-D-N-Y-V-R-K-E-H-P-L-H-C-A-G-S-F-K-S-E-G-F-G-I-T-L-F-E-R-L-E-G-R-D-P-N-T-L-V-G-L-P-L-I-A-L-C-Q-M-L-R-R-E-G-K-N-P-L-M-G"} +{"text": "### FUNCTION May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted ### SEQUENCE -M-N-E-A-V-S-P-G-A-L-S-T-L-F-T-D-A-R-T-H-N-G-W-R-E-T-P-V-S-D-E-T-L-R-E-I-Y-A-L-M-K-W-G-P-T-S-A-N-C-S-P-T-R-I-V-F-I-R-T-A-E-G-K-E-R-L-R-P-A-L-S-S-G-N-L-Q-K-T-L-T-A-P-V-T-A-I-V-A-W-D-S-E-F-Y-E-R-L-P-Q-L-F-P-H-G-D-A-R-S-W-F-T-S-S-P-Q-L-A-E-E-T-A-F-R-N-S-S-M-Q-A-A-Y-L-I-V-A-C-R-A-L-G-L-D-T-G-P-M-S-G-F-D-R-Q-Y-V-D-D-A-F-F-A-G-S-T-L-K-S-N-L-L-I-N-I-G-Y-G-D-S-S-K-L-F-A-R-L-P-R-L-S-F-E-E-A-C-G-L-L"} +{"text": "### FUNCTION Involved in the biogenesis of TorA Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor ### SEQUENCE -M-T-T-L-T-A-Q-Q-I-A-C-V-Y-A-W-L-A-Q-L-F-S-R-E-L-D-D-E-Q-L-T-Q-I-A-S-A-Q-M-A-E-W-F-S-L-L-K-S-E-P-P-L-T-A-A-V-N-G-L-E-N-S-I-A-T-L-T-V-R-D-D-A-R-L-E-L-A-A-D-F-C-G-L-F-L-M-T-D-K-Q-A-A-L-P-Y-A-S-A-Y-K-Q-D-E-Q-E-I-K-R-L-L-V-E-A-G-M-E-T-S-G-N-F-N-E-P-A-D-H-L-A-I-Y-P-E-L-L-S-H-L-H-F-S-L-G-E-G-T-V-P-A-R-R-I-D-G-L-R-Q-K-T-L-T-A-L-R-E-W-L-P-E-F-A-A-R-C-R-Q-Y-D-R-F-G-F-Y-A-A-L-S-Q-L-L-L-V-L-V-E-C-D-Y-Q-K-R"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine ### SEQUENCE -M-L-I-F-E-G-K-E-I-E-T-D-T-E-G-Y-L-K-E-S-S-Q-W-S-E-P-L-A-V-V-I-A-E-N-E-G-I-A-L-S-P-E-H-W-E-V-V-R-F-V-R-D-F-Y-L-E-F-N-T-S-P-A-I-R-M-L-V-K-A-M-A-N-K-F-G-E-E-K-G-N-S-R-Y-L-Y-R-L-F-P-K-G-P-A-K-Q-A-T-K-I-A-G-L-P-K-P-V-K-C-I"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-E-L-T-T-R-T-L-P-S-R-K-H-I-A-L-V-A-H-D-H-C-K-Q-M-L-M-S-W-V-E-R-H-Q-P-L-L-E-Q-H-V-L-Y-A-T-G-T-T-G-N-L-I-S-R-A-T-G-M-N-V-N-A-M-L-S-G-P-M-G-G-D-Q-Q-V-G-A-L-I-S-E-G-K-I-D-V-L-I-F-F-W-D-P-L-N-A-V-P-H-D-P-D-V-K-A-L-L-R-L-A-T-V-W-N-I-P-V-A-T-N-V-A-T-A-D-F-I-I-Q-S-P-H-F-N-D-A-V-D-I-L-I-P-D-Y-Q-R-Y-L-A-D-R-L-K"} +{"text": "### FUNCTION Component of the SOS system and an inhibitor of cell division Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments In the presence of GTP, binds a polymerization-competent form of FtsZ in a 11 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division ### SEQUENCE -M-Y-T-S-G-Y-A-H-R-S-S-S-F-S-S-A-A-S-K-I-A-R-V-S-T-E-N-T-T-A-G-L-I-S-E-V-V-Y-R-E-D-Q-P-M-M-T-Q-L-L-L-L-P-L-L-Q-Q-L-G-Q-Q-S-R-W-Q-L-W-L-T-P-Q-Q-K-L-S-R-E-W-V-Q-A-S-G-L-P-L-T-K-V-M-Q-I-S-Q-L-S-P-C-H-T-V-E-S-M-V-R-A-L-R-T-G-N-Y-S-V-V-I-G-W-L-A-D-D-L-T-A-E-E-H-A-E-L-V-D-A-A-N-E-G-N-A-M-G-F-I-M-R-P-V-S-A-S-S-H-A-T-R-Q-L-S-G-L-K-I-H-S-N-L-Y-H"} +{"text": "### FUNCTION Required for spatial organization of the terminus region of the chromosome during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-Q-L-E-N-L-E-S-G-W-K-W-K-Y-L-V-K-K-H-R-E-G-E-L-I-T-R-Y-I-E-A-S-A-A-Q-E-A-V-D-E-L-L-S-L-E-N-E-P-V-L-V-N-G-W-I-D-K-H-M-N-P-E-L-V-N-R-M-K-Q-T-I-R-A-R-R-K-R-H-F-N-A-E-H-Q-H-T-R-K-K-S-I-D-L-E-F-I-V-W-Q-R-L-A-G-L-A-Q-R-R-G-K-T-L-S-E-T-I-V-Q-L-I-E-D-A-E-N-K-E-K-Y-A-N-K-M-S-S-L-K-Q-D-L-Q-A-L-L-G-K-E"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-R-G-L-R-P-A-L-S-T-F-L-F-L-L-L-I-T-G-G-V-Y-P-L-L-T-T-A-L-G-Q-W-W-F-P-W-Q-A-N-G-S-L-I-R-E-G-D-T-V-R-G-S-A-L-I-G-Q-N-F-T-G-N-G-Y-F-H-G-R-P-S-A-T-A-E-M-P-Y-N-P-Q-A-S-G-G-S-N-L-A-V-S-N-P-E-L-D-K-Q-I-A-A-R-V-A-A-L-R-A-A-N-P-D-A-S-T-N-V-P-V-E-L-V-T-A-S-A-S-G-L-D-N-N-I-T-P-Q-A-A-A-W-Q-I-P-R-V-A-K-A-R-N-L-S-V-E-Q-L-T-Q-L-I-A-K-Y-S-Q-Q-P-L-V-K-Y-I-G-Q-P-V-V-N-I-V-E-L-N-L-A-L-D-K-L-D-E"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-Q-V-I-L-D-L-Q-L-A-C-E-D-N-S-G-L-P-E-E-S-Q-F-Q-T-W-L-N-A-V-I-P-Q-F-Q-E-E-S-E-V-T-I-R-V-V-D-T-A-E-S-H-S-L-N-L-T-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-V-P-P-G-M-E-M-S-L-L-G-D-L-V-I-C-R-Q-V-V-E-K-E-A-Q-E-Q-G-K-P-L-E-A-H-W-A-H-M-V-V-H-G-S-L-H-L-L-G-Y-D-H-I-E-D-D-E-A-E-E-M-E-A-I-E-T-E-I-M-L-A-L-G-Y-E-D-P-Y-I-A-E-K-E"} +{"text": "### FUNCTION Transfers 2- of the citrate lyase to yield holo-acyl carrier protein ### SEQUENCE -M-H-L-L-P-E-L-A-S-H-H-A-V-S-I-P-E-L-L-V-S-R-D-E-R-Q-A-R-Q-H-A-W-L-K-R-H-P-V-P-L-V-S-F-T-V-V-A-P-G-P-I-K-D-S-E-V-T-R-R-I-F-N-H-G-V-T-A-L-R-A-L-A-A-K-Q-G-W-Q-I-Q-E-Q-A-A-L-V-S-A-S-G-P-E-G-M-L-S-I-A-A-P-A-R-D-L-K-L-A-T-I-E-L-E-H-S-H-P-L-G-R-L-W-D-I-D-V-L-T-P-E-G-D-I-L-S-R-R-D-Y-S-L-P-P-R-R-C-L-L-C-E-Q-S-A-A-V-C-A-R-G-K-T-H-Q-L-T-D-L-L-N-R-M-E-A-L-L-N-D-V-D-A-C-N-V-N"} +{"text": "### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate -ureidoglycolate, generating urea and glyoxylate Involved in the anaerobic utilization of allantoin as sole nitrogen source Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate ### SEQUENCE -M-K-L-Q-V-L-P-L-S-Q-E-A-F-C-A-Y-G-D-V-I-E-T-Q-K-R-D-F-F-H-I-N-N-G-L-V-E-R-Y-H-D-L-A-L-V-E-I-L-E-Q-D-R-T-L-I-S-I-N-R-A-Q-P-A-N-L-P-L-T-I-H-E-L-E-R-H-P-L-G-T-Q-A-F-I-P-M-K-G-E-V-F-V-V-V-V-A-L-G-D-D-K-P-D-L-S-T-L-R-A-F-I-T-N-G-E-Q-G-V-N-Y-H-R-N-V-W-H-H-P-L-F-A-W-Q-R-V-T-D-F-L-T-I-D-R-G-G-S-D-N-C-D-V-E-S-I-P-E-Q-E-L-C-F-A"} +{"text": "### FUNCTION Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP ### SEQUENCE -M-N-F-L-A-H-L-H-L-A-H-L-A-E-S-S-L-S-G-N-L-L-A-D-F-V-R-G-N-P-E-E-S-F-P-P-D-V-V-A-G-I-H-M-H-R-R-I-D-V-L-T-D-N-L-P-E-V-R-E-A-R-E-W-F-R-N-E-T-R-R-V-A-P-I-T-L-D-V-M-W-D-H-F-L-S-R-H-W-S-Q-L-S-P-D-F-P-L-Q-E-F-T-C-Y-A-R-E-Q-V-M-T-I-L-P-D-S-P-Q-R-F-I-N-L-N-N-Y-L-W-S-E-Q-W-L-V-R-Y-R-D-M-D-F-I-Q-S-V-L-N-G-M-A-S-R-R-P-R-L-D-A-L-R-D-S-W-Y-D-L-D-A-H-Y-D-A-L-E-T-R-F-W-Q-F-Y-P-R-M-M-E-Q-A-S-R-K-A-L"} +{"text": "### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway ### SEQUENCE -M-K-N-L-I-A-E-L-L-F-K-L-A-Q-K-E-E-E-S-K-E-L-C-A-Q-V-E-A-L-E-I-I-V-T-A-M-L-R-N-M-A-Q-N-D-Q-Q-R-L-I-D-Q-V-E-G-A-L-Y-E-V-K-P-D-A-S-I-P-D-D-D-T-E-L-L-R-D-Y-V-K-K-L-L-R-H-P-R-Q"} +{"text": "### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-L-G-M-Q-S-I-R-R-R-Q-L-I-D-A-T-L-E-A-I-N-E-V-G-M-H-D-A-T-I-A-Q-I-A-R-R-A-G-V-S-T-G-I-I-S-H-Y-F-R-D-K-N-G-L-L-E-A-T-M-R-D-I-T-S-Q-L-R-D-A-V-L-N-R-L-H-A-L-P-Q-G-S-A-E-R-R-L-Q-A-I-V-G-G-N-F-D-E-T-Q-V-S-S-A-A-M-K-A-W-L-A-F-W-A-S-S-M-H-Q-P-M-L-Y-R-L-Q-Q-V-S-S-R-R-L-L-S-N-L-V-S-E-F-R-R-E-L-P-R-Q-Q-A-Q-E-A-G-Y-G-L-A-A-L-I-D-G-L-W-L-R-A-A-L-S-G-K-P-L-D-K-P-L-A-H-S-L-T-R-H-F-I-T-Q-H-L-P-T-D"} +{"text": "### FUNCTION Part of the ecpRABCDE operon, which encodes the Ecoli common pilus ### SEQUENCE -M-T-W-Q-N-D-Y-S-R-D-Y-E-V-K-N-H-M-E-C-Q-N-R-S-D-K-Y-I-W-S-P-H-D-A-Y-F-Y-K-G-L-S-E-L-I-V-D-I-D-R-L-I-Y-L-S-L-E-K-I-R-K-D-F-V-F-I-N-L-N-T-D-S-L-T-E-F-I-N-R-D-N-E-W-L-S-A-V-K-G-K-Q-V-V-L-I-A-A-R-K-S-E-A-L-A-N-Y-W-Y-Y-N-S-N-I-R-G-V-V-Y-A-G-L-S-R-D-I-R-K-E-L-A-Y-V-I-N-G-R-F-L-R-K-D-I-K-K-D-K-I-T-D-R-E-M-E-I-I-R-M-T-A-Q-G-M-L-P-K-S-I-A-R-I-E-N-C-S-V-K-T-V-Y-T-H-R-R-N-A-E-A-K-L-Y-S-K-L-Y-K-L-V-Q"} +{"text": "### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-T-L-P-S-G-H-P-K-S-R-L-I-K-K-F-T-A-L-G-P-Y-I-R-E-G-K-C-E-D-N-R-F-F-F-D-C-L-A-V-C-V-N-V-K-P-A-P-E-V-R-E-F-W-G-W-W-M-E-L-E-A-Q-E-S-R-F-T-Y-S-Y-Q-F-G-L-F-D-K-A-G-D-W-T-S-V-R-I-K-D-A-E-V-V-E-R-L-E-H-T-L-R-E-F-H-E-K-L-R-E-L-L-A-T-L-N-L-K-L-E-P-A-D-D-F-R-D-E-P-V-K-L-T-A"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-S-E-T-I-T-V-N-C-P-T-C-G-K-T-V-V-W-G-E-I-S-P-F-R-P-F-C-S-K-R-C-Q-L-I-D-L-G-E-W-A-A-E-E-K-R-I-P-S-S-S-D-L-S-E-S-D-D-W-S-E-E-P-K-Q"} +{"text": "### FUNCTION Overproduction of CaiE stimulates the activity of CaiB and CaiD ### SEQUENCE -M-S-Y-Y-A-F-E-G-L-I-P-V-V-H-P-T-A-F-V-H-P-S-A-V-L-I-G-D-V-I-V-G-A-G-V-Y-I-G-P-L-A-S-L-R-G-D-Y-G-R-L-I-V-Q-A-G-A-N-I-Q-D-G-C-I-M-H-G-Y-C-D-T-D-T-I-V-G-E-N-G-H-I-G-H-G-A-I-L-H-G-C-V-I-G-R-D-A-L-V-G-M-N-S-V-I-M-D-G-A-V-I-G-E-E-S-I-V-A-A-M-S-F-V-K-A-G-F-R-G-E-K-R-Q-L-L-M-G-T-P-A-R-A-V-R-S-V-S-D-D-E-L-H-W-K-R-L-N-T-K-E-Y-Q-D-L-V-G-R-C-H-A-A-L-H-E-T-Q-P-L-R-Q-M-E-E-N-R-P-R-L-Q-G-T-T-D-V-T-P-K-R"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-Q-Y-E-L-M-I-I-L-D-P-S-Q-D-E-R-T-V-A-P-S-L-D-K-F-L-E-V-V-R-K-D-K-G-D-V-V-K-V-D-V-W-G-K-R-R-L-A-Y-P-I-N-K-K-E-E-G-I-Y-A-V-I-D-L-K-C-E-S-A-T-V-L-E-L-D-R-V-L-N-L-N-D-G-V-L-R-T-K-V-L-R-L-D-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-I-L-T-A-A-V-E-N-L-G-V-A-G-D-I-V-E-V-K-D-G-Y-G-R-N-L-L-L-P-R-G-L-A-I-P-A-T-P-G-A-E-K-Q-I-E-G-I-K-R-A-Q-E-A-R-A-I-R-D-L-D-H-A-R-E-V-K-A-Q-L-E-A-L-E-G-V-K-V-A-V-R-T-S-E-S-G-K-L-F-G-S-V-K-A-D-D-I-V-D-A-V-K-A-A-G-G-P-N-L-D-K-R-A-I-V-L-P-K-N-L-V-K-T-T-G-K-Y-Q-V-E-A-K-I-H-E-G-I-V-S-R-V-K-F-E-V-V-A-A"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-T-V-R-P-I-V-I-H-G-D-P-V-L-H-N-P-T-R-E-V-T-E-P-I-S-E-L-Q-E-L-I-A-D-M-Y-E-T-M-E-V-A-N-G-V-G-L-A-A-N-Q-I-G-V-S-K-R-I-F-V-F-N-C-P-D-D-E-G-T-M-H-R-G-C-F-I-N-P-V-L-E-T-S-E-I-P-E-T-M-P-A-D-D-G-S-D-E-E-G-C-L-S-V-P-G-E-G-F-P-T-G-R-A-D-W-A-K-V-T-G-L-N-E-D-G-E-E-W-S-M-E-G-T-G-F-L-A-R-C-F-Q-H-E-V-G-H-L-D-G-V-V-Y-T-D-T-L-I-G-R-W-K-R-L-A-K-K-T-I-K-A-N-G-W-T-E-P-G-L-T-W-T-P-G-V-D-E-D-P-F-G-H-D-V"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Q-V-S-I-P-V-C-Y-P-C-P-S-F-P-Q-T-R-P-F-A-G-D-G-R-K-F-G-R-V-D-S-G-F-M-P-K-L-W-E-G-L-S-V-G-A-G-A-A-V-G-A-C-A-R-L-A-L-T-M-Q-F-G-E-G-L-W-P-I-L-A-I-N-M-L-G-S-F-L-M-G-R-Y-R-P-G-P-F-W-G-T-G-V-L-G-G-F-T-T-F-S-A-F-A-V-V-L-V-D-V-P-L-P-H-A-V-A-Y-L-T-V-T-V-V-S-C-V-A-A-W-L-M-G-N-R-W-S-A"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-C-S-S-P-S-A-P-T-A-E-P-D-V-E-M-D-V-H-T-V-S-S-E-N-L-P-W-L-C-I-V-W-D-D-P-V-N-L-M-S-Y-V-T-Y-V-F-Q-T-V-L-G-Y-S-R-K-R-A-N-E-L-M-M-Q-V-H-T-E-G-K-A-V-V-S-S-G-E-K-D-K-V-E-G-D-V-K-K-L-H-V-A-G-L-W-A-T-M-Q-Q-A-G"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-S-I-G-T-D-L-V-H-I-P-A-F-A-D-Q-L-A-Q-P-G-S-S-F-M-D-V-F-G-A-G-E-R-R-L-A-S-R-R-A-G-N-R-N-A-E-H-L-A-G-R-W-A-A-K-E-A-F-I-K-A-W-S-Q-A-I-Y-G-Q-P-P-V-I-P-E-E-D-V-Q-W-A-L-I-E-V-R-A-D-R-W-G-R-V-A-L-D-I-A-P-S-L-D-T-Q-V-R-E-S-I-G-D-Y-T-T-S-L-S-I-S-H-D-G-D-Y-A-T-A-V-C-V-L-S-Y-A-V-A-T-E-N-R"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-D-N-L-N-M-T-A-P-G-A-G-T-G-Y-S-G-D-I-F-D-R-L-L-R-E-R-I-I-F-L-G-S-Q-V-D-D-E-I-A-N-K-L-C-A-Q-I-L-L-L-S-A-E-D-P-T-R-D-I-S-L-Y-I-N-S-P-G-G-S-V-T-A-G-M-A-I-Y-D-T-M-K-Y-S-P-C-D-I-A-T-Y-G-M-G-L-A-A-S-M-G-Q-F-L-L-S-G-G-T-P-G-K-R-Y-A-L-P-H-A-R-I-M-M-H-Q-P-S-A-G-V-G-G-T-A-A-D-I-A-I-Q-A-E-Q-F-A-Q-T-K-R-E-M-A-K-L-I-A-E-H-T-G-Q-T-F-E-Q-V-T-K-D-S-D-R-D-R-W-F-T-A-E-Q-A-K-E-Y-G-L-V-D-H-V-I-T-L-A-E-G-P-I-S-N"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-K-T-G-G-K-Q-Y-K-V-A-E-G-D-L-V-K-V-E-K-I-E-G-E-P-G-A-S-V-A-L-T-P-V-L-L-V-D-G-A-D-V-T-T-A-A-D-K-L-A-S-V-S-V-N-T-E-I-V-E-H-T-K-G-P-K-I-K-I-L-K-Y-K-N-K-T-G-Y-K-K-R-Q-G-H-R-Q-K-L-T-V-L-K-V-T-G-I-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-I-K-R-N-K-T-N-E-K-A-R-L-R-N-Q-A-I-R-S-A-V-R-T-E-I-R-K-F-H-A-A-I-D-G-G-D-K-A-A-A-E-S-Q-L-R-V-A-S-R-A-L-D-K-A-V-T-K-G-V-F-H-R-N-N-A-A-N-K-K-S-S-L-A-R-A-F-N-K-L-G"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-I-E-V-F-N-E-S-G-Y-D-G-V-N-E-E-M-L-I-D-V-L-S-F-A-L-G-E-M-D-I-H-P-D-A-E-A-S-I-H-I-V-D-S-D-T-I-A-E-L-H-V-K-W-L-D-L-E-G-P-T-D-V-M-S-F-P-M-D-E-L-T-P-G-Y-S-R-P-D-G-G-A-P-G-P-A-M-L-G-D-I-V-L-C-P-E-F-A-E-K-Q-A-T-K-A-G-H-D-L-S-H-E-L-A-L-L-T-V-H-G-C-L-H-L-L-G-Y-D-H-V-E-P-A-Q-E-R-E-M-F-A-L-Q-N-E-L-L-A-D-W-Y-D-D-V-D-R-R-G-V-V-Y-Q-P-K-P-T-G-P-G-A-F-P-T-A-A-D-R-L-E-L-D-Q-T-M-I-A-E-E-Q-G-E-P-G-E-S-G-A-S-A-R"} +{"text": "### FUNCTION Part of cytochrome c oxidase, its function is unknown ### SEQUENCE -M-K-S-S-S-K-I-M-Y-G-L-T-V-F-L-A-A-M-A-V-I-Y-I-F-G-T-M-Y-V-D-D-R-G-S-V-M-G-L-E-W-V-G-A-T-A-L-V-L-S-T-A-L-T-L-M-L-G-V-Y-I-H-I-T-E-R-R-T-D-V-L-P-E-D-W-E-E-A-E-V-A-D-K-A-G-T-L-G-F-F-S-P-G-S-I-W-P-A-A-M-S-G-A-V-G-L-L-G-F-G-I-I-F-M-H-Y-W-L-I-L-V-G-A-L-A-L-T-Y-T-I-A-K-L-N-F-Q-Y-G-V-P-R-E-K-H"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-T-E-L-Q-I-G-R-V-I-K-S-H-G-I-R-G-E-V-V-V-E-V-T-T-D-D-P-D-I-R-Y-A-P-G-E-V-L-H-G-R-Q-T-G-R-E-H-T-L-T-I-D-T-A-R-A-H-Q-G-R-L-L-I-K-F-E-E-I-P-D-R-T-A-A-D-S-L-R-G-T-R-F-F-A-P-P-L-E-R-E-D-D-E-E-G-F-Y-D-H-E-L-E-G-L-R-I-I-H-D-G-A-D-I-G-V-V-T-G-V-M-H-G-P-A-G-E-I-L-E-V-E-L-T-S-G-K-E-V-L-I-P-F-V-H-A-I-V-P-E-V-D-L-E-A-G-T-A-T-I-T-P-P-D-G-L-L-D-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-I-L-D-K-V-D-S-A-Y-L-R-D-D-V-P-A-F-R-P-G-D-T-L-D-V-H-V-K-V-I-E-G-T-N-T-R-T-Q-L-F-K-G-V-V-I-R-R-Q-G-S-G-I-R-E-T-F-T-V-R-K-V-S-F-G-I-G-V-E-R-T-F-P-V-H-S-P-N-L-E-K-I-E-V-V-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-E-L-R-G-K-A-A-R-I-K-E-K-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-D-E-I-L-F-D-S-E-E-R-M-S-N-T-V-E-H-T-R-E-D-L-I-T-I-R-T-G-R-A-N-P-A-M-F-N-G-V-L-A-E-Y-Y-G-V-P-T-P-I-T-Q-M-S-S-I-S-V-P-E-P-R-M-L-I-I-K-P-Y-E-M-S-S-M-G-V-I-E-N-A-I-R-N-S-D-L-G-V-N-P-T-N-D-G-Q-V-L-R-V-T-I-P-Q-L-T-E-E-R-R-R-D-M-V-K-I-A-K-G-K-G-E-D-G-K-I-A-I-R-N-V-R-R-K-G-M-E-Q-L-K-K-L-Q-K-D-G-E-F-G-E-D-E-V-A-A-A-E-K-E-L-D-K-I-T-A-H-Y-V-E-Q-V-D-E-I-V-A-R-K-E-A-E-L-M-E-V"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-F-P-T-A-E-E-L-T-A-L-I-A-P-V-V-A-T-R-H-L-D-V-E-G-L-R-V-T-K-A-G-P-K-S-T-V-A-I-K-L-D-S-D-S-R-P-D-L-D-L-L-E-V-V-S-Q-E-I-G-E-L-F-D-A-A-E-A-R-G-E-L-S-F-G-A-G-Y-L-L-E-V-S-T-P-G-V-D-M-P-L-T-Q-P-R-H-W-R-R-N-R-T-R-L-V-S-L-D-V-D-G-K-K-R-I-A-R-I-G-A-L-N-A-E-E-T-A-V-I-L-I-E-R-N-K-K-A-L-S-V-T-V-L-E-L-A-N-S-P-R-A-V-V-E-I-E-F-A-K-P-A-Q-D-E-L-D-L-A-G-R-T-F-D-E-A-V-E-E-T-D-H"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-V-D-N-A-R-A-A-R-M-A-K-R-I-Q-T-I-V-A-S-A-I-E-R-E-I-K-D-R-R-L-E-Y-I-T-I-T-D-V-T-M-T-G-D-L-H-D-A-T-V-F-Y-T-V-R-G-E-N-V-G-D-E-P-D-L-E-A-A-A-E-A-L-H-R-A-R-G-Q-L-R-K-I-V-G-E-Q-L-G-V-R-F-T-P-T-L-T-Y-R-V-D-T-V-P-E-A-S-A-H-M-E-A-L-L-E-R-A-R-Q-R-D-A-E-L-A-K-L-K-E-N-A-V-P-A-G-D-P-N-P-Y-K-S-D-T-R-E-E-D-E-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-S-E-Q-K-K-S-I-L-A-E-Y-G-L-H-E-T-D-T-G-S-P-E-A-Q-I-A-M-L-T-N-R-I-N-T-L-T-E-H-L-K-F-H-K-H-D-H-H-S-R-R-G-L-L-L-L-V-G-R-R-R-G-L-L-K-Y-L-A-D-N-N-V-D-R-Y-R-D-L-I-A-R-L-G-L-R-R"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Y-C-P-F-C-Q-H-G-H-S-R-V-I-D-S-R-V-I-E-A-G-S-A-I-R-R-R-R-E-C-S-Q-C-Q-G-R-F-T-T-I-E-K-A-V-L-L-V-L-K-R-N-G-V-T-E-P-F-S-R-E-K-V-V-T-G-V-R-R-A-C-Q-G-R-D-V-S-D-D-S-L-K-R-L-A-Q-Q-V-E-E-T-V-R-S-S-G-S-S-Q-V-R-A-N-D-I-G-L-A-I-L-D-P-L-R-E-L-D-E-V-A-Y-L-R-F-A-S-V-Y-K-S-F-E-S-A-D-D-F-E-K-E-I-R-L-M-R-R-Q-S-R-E-K-Q-V-Q-Q-G"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-I-L-S-H-R-W-Q-C-T-I-V-P-V-D-S-G-R-Q-R-R-A-Y-P-E-G-V-T-E-N-L-N-T-I-D-S-I-R-L-L-R-L-D-P-G-L-P-M-P-R-R-A-H-R-G-D-A-G-V-D-L-H-S-T-T-D-V-V-I-A-P-G-H-R-E-L-V-G-T-G-V-A-I-A-L-P-L-G-T-V-G-L-I-H-P-R-S-G-L-A-A-R-E-G-L-S-I-V-N-A-P-G-T-V-D-A-D-Y-R-G-E-I-K-V-C-L-I-N-L-D-P-S-T-P-I-T-I-T-R-G-D-R-I-A-Q-L-I-I-Q-R-V-E-L-V-D-F-V-E-V-D-E-L-D-E-T-T-R-G-D-Q-G-H-G-S-T-G-R-G-S-T-A"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-K-F-I-K-H-T-G-V-G-V-P-L-Q-R-S-N-V-D-T-D-Q-I-I-P-A-V-Y-L-K-R-V-T-R-T-G-F-E-D-G-L-F-S-N-W-R-K-N-D-P-D-F-V-L-N-Q-D-T-Y-K-N-G-S-V-L-I-A-G-P-D-F-G-T-G-S-S-R-E-H-A-V-W-A-L-M-D-Y-G-F-R-A-V-F-S-S-R-F-A-D-I-F-R-G-N-S-G-K-A-G-L-L-T-G-I-M-E-Q-S-D-I-E-L-L-W-K-L-M-E-Q-T-P-G-L-E-M-T-V-D-L-E-N-Q-T-V-V-A-G-D-T-V-I-S-F-E-V-D-P-Y-I-R-W-R-L-M-E-G-L-D-D-V-G-L-T-L-R-K-V-D-E-I-E-A-Y-E-A-K-R-P-A-F-K-P-S-A-L"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-P-E-I-S-R-D-Q-V-A-H-L-A-K-L-A-R-L-A-L-S-E-E-E-L-Q-Q-F-A-G-Q-I-D-D-I-V-G-H-V-S-A-V-Q-N-V-D-A-E-G-V-E-P-M-S-H-P-H-S-I-M-T-T-M-R-D-D-V-V-V-K-T-L-T-P-E-Q-A-L-D-Q-A-P-A-V-E-D-G-R-F-M-V-P-Q-I-L-G-E-G-D"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-E-I-T-V-E-L-V-S-V-E-R-M-L-W-S-G-Q-A-S-I-V-T-A-Q-T-T-E-G-E-I-G-V-L-P-D-H-E-P-M-L-G-Q-L-V-E-N-G-V-V-T-I-Q-P-T-D-G-D-R-L-V-A-G-V-Q-G-G-F-L-S-V-S-K-E-K-V-T-I-L-A-D-F-A-V-W-A-H-E-V-D-S-A-S-A-E-A-D-L-N-S-D-D-E-L-A-K-A-R-A-E-A-G-L-R-A-V-R-R-S-S-E-G-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-N-P-I-Y-I-L-A-H-A-N-A-E-Y-L-P-L-E-S-G-N-S-I-L-L-P-K-A-Y-D-I-V-W-S-L-I-P-F-L-I-I-L-F-V-F-W-K-F-V-L-P-K-F-Q-E-V-L-T-E-R-E-D-R-I-K-G-G-I-Q-R-A-E-A-A-Q-A-E-A-K-A-A-L-E-K-Y-N-A-Q-L-A-E-A-R-T-E-A-A-E-I-R-E-Q-A-R-E-R-G-K-Q-I-E-V-E-M-K-A-K-A-E-E-E-S-N-R-I-I-E-A-G-T-K-Q-L-M-A-Q-R-E-Q-V-V-N-E-L-R-R-E-M-G-Q-N-S-I-N-L-A-E-H-L-L-G-D-Q-L-S-D-D-V-K-R-S-G-T-I-D-R-F-L-A-D-L-D-T-V-A-P-N-G-K"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-S-N-V-G-W-G-E-I-L-L-L-F-I-V-G-L-I-V-I-G-P-E-R-L-P-R-L-M-E-D-L-K-A-A-I-V-A-A-R-T-A-I-N-N-A-K-Q-N-L-D-T-D-F-G-E-E-F-D-E-I-R-K-P-M-A-Q-I-A-Q-I-R-S-M-S-P-K-T-A-I-T-R-A-L-F-D-G-D-D-S-F-L-D-S-F-D-P-K-K-I-M-A-D-D-T-A-G-Q-A-H-R-Q-Q-V-A-K-T-G-T-T-P-E-H-A-E-V-V-E-R-P-A-D-R-I-D-P-T-Q-S-P-N-T-P-G-K-N-N-D-G-G-K-P-P-A-G-G-G-Y-T-W-T-D-L-I"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-N-D-S-P-V-L-V-V-G-L-G-N-P-G-P-K-Y-V-G-T-R-H-N-I-G-F-E-V-V-E-E-L-V-G-R-N-Y-A-N-F-S-V-H-K-R-S-N-T-E-I-A-Q-L-P-G-L-I-V-A-K-P-R-S-F-M-N-L-S-G-T-P-I-R-A-L-C-D-F-F-K-I-S-P-A-N-V-L-V-V-H-D-E-L-D-L-D-F-G-Q-V-K-L-R-Q-G-G-G-D-H-G-H-N-G-L-K-S-T-S-R-S-L-G-T-K-D-Y-W-K-L-S-V-G-I-G-R-P-P-G-R-M-D-P-A-T-F-V-L-K-P-F-S-K-Q-E-Q-D-S-V-P-I-M-A-A-D-A-A-D-L-I-E-E-H-I-R-T-L"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-I-T-E-I-I-G-N-I-H-E-Q-P-E-L-R-T-H-H-A-E-T-I-T-L-V-D-D-A-L-T-K-R-I-Q-R-L-V-S-D-H-G-S-E-L-G-L-R-L-P-S-G-H-P-P-L-R-D-G-D-V-L-H-S-D-G-E-N-S-I-L-I-A-V-A-P-T-D-V-L-M-I-R-P-G-T-L-R-D-M-A-F-V-A-H-S-L-G-N-R-H-L-P-A-Q-F-D-G-D-V-M-I-V-R-Y-D-N-T-V-V-D-F-L-E-H-Y-G-V-R-Y-E-R-R-S-T-V-M-P-T-P-F-R-H-S-E-H-T-H"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-N-E-Q-R-K-A-I-V-A-R-Y-A-E-R-R-A-E-L-K-A-I-I-R-N-P-N-T-S-D-E-D-R-L-D-A-Q-F-E-L-N-R-Q-P-R-D-A-A-Q-V-R-V-R-N-R-D-A-H-D-G-R-P-R-G-Y-L-R-K-F-G-L-S-R-V-R-M-R-E-M-A-H-R-G-E-L-P-G-V-R-K-S-S-W"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-K-K-K-V-D-E-N-N-Q-V-L-A-T-N-R-K-A-R-H-D-Y-Q-I-L-D-T-W-E-A-G-V-V-L-L-G-T-E-I-K-S-L-R-E-G-K-A-S-L-V-D-A-F-A-V-I-D-N-G-E-V-W-L-H-N-L-H-I-P-T-Y-S-M-G-S-W-T-N-H-S-P-K-R-T-R-K-L-L-L-H-R-R-E-I-D-S-L-M-G-K-V-R-D-G-N-R-T-L-V-P-L-K-L-Y-L-V-N-G-R-V-K-L-E-L-G-L-A-Q-G-K-Q-D-Y-D-K-R-Q-D-I-K-R-R-T-E-E-R-E-V-T-R-E-L-G-R-R-I-K-G-I-N-A"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-Q-I-V-L-A-S-Q-S-P-S-R-L-M-I-L-R-Q-A-G-V-E-P-V-I-H-P-A-H-V-D-E-D-A-I-I-A-Q-L-A-G-A-E-P-D-E-I-V-T-R-L-A-L-A-K-A-Q-A-I-A-P-E-H-P-G-D-V-V-I-G-G-D-S-M-L-L-L-D-G-Q-L-Q-G-K-P-H-T-P-E-A-T-I-E-R-W-R-Q-Q-R-G-R-T-A-H-L-I-T-G-H-A-I-C-L-G-E-R-R-V-V-E-A-S-R-T-T-I-H-F-A-D-A-S-D-T-D-I-E-A-Y-A-R-S-G-E-P-L-Q-C-A-G-A-F-T-L-E-A-L-G-G-W-F-I-D-A-I-E-G-D-P-S-S-V-I-G-L-S-L-P-V-V-R-R-A-L-Y-S-F-G-L-N-A-S-D-F-W-T-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-S-T-Y-H-P-K-S-G-D-I-T-R-K-W-Y-V-I-D-A-T-D-V-V-L-G-R-L-A-T-H-A-A-D-L-L-R-G-K-G-K-P-L-F-A-P-N-V-D-C-G-D-H-V-I-I-I-N-A-D-K-V-A-I-T-S-N-K-R-D-R-E-M-R-Y-R-H-S-G-Y-P-G-G-L-K-S-M-T-L-G-R-S-L-E-L-H-P-E-R-V-L-E-E-S-I-T-G-M-M-P-H-N-K-L-T-A-A-S-V-K-K-L-H-V-F-A-G-S-E-H-P-Y-A-A-Q-K-P-E-T-Y-E-I-K-K-V-A-Q"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-G-A-I-E-V-E-G-R-V-V-E-P-L-P-N-A-M-F-R-V-E-L-D-N-G-H-K-V-L-A-H-I-S-G-K-M-R-Q-H-Y-I-R-I-L-P-E-D-R-V-V-V-E-L-S-P-Y-D-L-T-R-G-R-I-V-Y-R-Y-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-N-T-E-N-K-Q-K-R-V-S-V-G-K-D-I-A-T-R-R-R-V-A-R-A-R-R-H-F-R-I-R-K-T-L-R-G-T-P-E-A-P-R-L-V-V-H-R-S-S-R-H-M-H-V-Q-I-I-D-D-L-A-G-H-T-L-A-A-A-S-S-I-E-P-E-V-R-A-V-E-G-D-K-K-A-K-G-A-K-V-G-Q-L-I-A-E-R-A-K-A-A-G-I-E-Q-V-V-F-D-R-A-G-Y-K-Y-H-G-R-V-A-A-L-A-D-A-A-R-E-G-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-N-P-I-A-I-P-S-G-V-E-V-K-I-D-G-R-L-V-D-V-K-G-P-K-G-N-L-N-V-T-L-P-E-P-I-T-A-S-I-E-N-N-E-I-L-V-T-R-P-D-D-H-R-N-S-R-S-M-H-G-L-S-R-S-L-V-N-N-L-V-V-G-V-T-E-G-Y-T-I-K-M-E-I-F-G-V-G-Y-R-V-A-L-K-G-K-N-L-E-F-S-L-G-Y-S-H-P-V-L-I-E-A-P-E-G-I-T-F-A-V-D-G-T-T-K-L-S-I-S-G-I-D-K-Q-K-V-G-Q-V-A-A-V-I-R-R-L-R-K-D-D-P-Y-K-G-K-G-I-R-Y-E-G-E-Q-I-R-R-K-V-G-K-T-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-I-A-D-M-L-S-R-V-R-N-A-N-N-A-H-H-D-T-V-S-M-P-S-S-K-L-K-A-N-I-A-E-I-L-K-Q-E-G-Y-I-E-S-Y-T-V-E-D-A-K-V-G-K-T-L-T-L-E-L-K-Y-T-G-N-R-V-R-S-I-A-G-L-R-R-V-S-K-P-G-L-R-V-Y-A-K-S-T-N-L-P-Q-V-L-G-G-L-G-V-A-I-I-S-T-S-Q-G-L-L-T-D-R-Q-A-T-E-K-G-V-G-G-E-V-L-A-Y-V-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-E-N-Y-T-P-R-L-K-S-R-Y-Q-D-E-I-R-P-N-L-Q-T-Q-F-E-F-S-N-V-M-Q-I-P-G-V-T-K-V-V-V-N-M-G-V-G-D-A-A-R-D-S-K-M-I-N-G-A-L-E-D-L-T-A-I-T-G-Q-K-P-Q-L-R-R-A-K-K-S-I-A-N-F-K-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-D-R-M-W-E-F-L-D-R-L-L-T-V-A-L-P-R-I-R-D-F-R-G-L-S-D-Q-Q-F-D-G-H-G-N-Y-T-F-G-L-T-E-Q-T-M-F-Y-E-I-D-V-D-K-I-D-R-P-R-G-M-D-I-T-V-V-T-T-A-V-T-D-D-E-G-R-A-L-L-R-E-L-G-F-P-F-K-G-E-D-G-K-K-Q"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-V-H-K-G-D-M-V-L-V-I-S-G-P-D-K-G-A-K-G-K-V-I-A-A-F-P-K-T-E-K-V-L-V-E-G-V-N-R-I-K-K-H-V-A-N-S-A-P-E-R-G-A-E-S-G-G-I-V-T-Q-E-A-P-I-H-V-S-N-V-M-V-I-D-A-D-G-N-P-T-R-V-G-F-R-V-D-E-N-G-K-K-V-R-V-S-R-R-S-G-K-D-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-I-A-D-N-T-G-A-R-E-I-L-C-I-R-V-L-G-G-S-T-R-R-F-A-G-I-G-D-V-I-V-A-T-V-K-E-A-A-P-G-G-N-V-K-S-G-E-I-V-K-A-V-I-V-R-T-K-K-E-T-R-R-A-D-G-S-Y-I-S-F-D-E-N-A-A-V-I-I-K-N-D-N-E-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-K-K-F-M-K-I-V-S-L-A-P-E-V-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-A-N-V-S-N-K-E-K-G-A-R-K-V-R-T-G-Y-V-V-S-D-K-M-Q-K-T-I-V-V-E-L-E-D-R-K-Q-H-A-L-Y-S-K-I-L-R-T-N-K-K-V-K-A-H-D-E-E-N-I-A-G-I-G-D-L-V-R-I-E-E-T-R-P-L-S-K-D-K-N-Y-R-L-I-E-I-I-E-K-A-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-I-P-K-R-V-K-Y-R-R-Q-H-R-P-T-R-S-G-I-S-K-G-G-N-R-V-T-F-G-E-Y-G-I-Q-A-L-E-P-A-Y-I-T-N-R-Q-I-E-S-A-R-I-A-I-N-R-H-V-K-R-G-G-K-V-W-I-N-I-F-P-D-R-P-L-T-Q-K-P-L-G-V-R-M-G-S-G-K-G-P-V-E-K-W-V-A-N-V-K-P-G-R-I-L-F-E-M-S-Y-P-D-E-A-M-A-L-E-A-L-R-R-A-G-Q-K-L-P-C-K-V-R-I-V-K-R-E-D-Q-L"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-D-N-I-T-S-A-R-A-T-A-R-F-V-R-V-S-P-M-K-A-R-R-V-I-D-L-V-R-G-K-T-V-V-E-A-L-S-I-L-K-Y-A-P-Q-A-A-S-E-P-V-A-K-V-V-A-S-A-A-A-N-A-E-N-N-F-G-L-D-P-R-T-L-V-I-S-E-A-Y-A-D-E-G-P-T-M-R-R-F-Q-P-R-A-Q-G-R-A-F-Q-I-R-K-R-S-S-H-I-T-V-V-V-E-S-Q-K-E-G-A-N"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-A-T-I-A-N-P-R-D-I-I-L-A-P-V-V-S-E-K-S-Y-G-L-M-E-Q-N-V-Y-T-F-F-V-A-R-D-A-N-K-T-Q-I-K-I-A-V-E-E-I-F-G-V-K-V-A-S-V-N-T-V-N-R-E-G-K-R-K-R-S-R-S-G-F-G-V-R-K-A-T-K-R-A-Y-V-T-L-R-E-G-S-D-S-I-D-I-F-N-G-S-V-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-S-A-A-P-K-R-P-V-V-K-D-P-V-Y-D-S-E-L-V-T-Q-L-V-N-K-I-L-L-D-G-K-K-S-T-A-E-R-I-V-Y-G-A-L-E-I-C-R-E-K-T-G-L-E-P-V-G-T-L-E-K-A-L-G-N-V-R-P-D-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-P-A-R-A-T-T-L-A-L-R-W-L-V-T-F-T-R-Q-R-R-E-N-T-M-V-E-R-L-A-N-E-I-M-D-A-A-N-G-L-G-A-S-V-K-R-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-L-T-K-D-E-L-I-E-A-F-K-E-M-T-L-I-E-L-S-E-F-V-K-E-F-E-E-V-F-E-V-T-A-A-A-P-V-A-V-A-A-A-G-A-A-G-G-E-A-A-A-A-E-E-K-D-E-F-D-V-V-L-E-D-A-G-A-K-K-I-G-V-I-K-V-V-R-E-L-V-S-G-L-G-L-K-E-A-K-E-L-V-E-G-A-P-K-A-I-L-E-G-A-N-K-D-D-A-E-A-A-K-A-K-L-E-E-A-G-A-K-V-T-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-N-P-K-N-E-A-A-L-A-E-L-K-A-Q-F-A-E-T-D-S-I-V-L-T-E-Y-R-G-L-T-V-A-Q-T-T-E-L-R-R-A-L-G-D-D-V-Q-Y-S-V-A-K-N-T-L-V-K-I-A-A-Q-E-A-G-V-E-G-L-D-D-L-L-T-G-P-T-A-V-A-F-I-K-G-E-A-V-D-T-A-K-V-L-K-K-F-G-D-D-N-K-A-F-V-V-K-G-G-Y-M-D-G-N-A-L-T-A-D-Q-V-K-A-I-A-E-L-D-N-R-E-T-T-L-A-K-L-A-G-A-M-K-G-N-L-A-K-A-A-G-L-F-N-A-P-A-S-Q-V-A-R-L-A-A-A-L-Q-E-K-K-D-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-P-K-K-K-K-V-T-G-L-I-K-L-Q-I-Q-A-G-Q-A-N-P-A-P-P-V-G-P-A-L-G-A-H-G-V-N-I-M-E-F-C-K-A-Y-N-A-A-T-E-N-Q-R-G-N-V-V-P-V-E-I-T-V-Y-E-D-R-S-F-D-F-K-L-K-T-P-P-A-A-K-L-L-L-K-A-A-G-L-Q-K-G-S-G-V-P-H-T-N-K-V-G-K-V-T-M-D-Q-I-R-E-I-A-E-T-K-K-E-D-L-N-A-R-D-I-D-A-A-A-K-I-I-A-G-T-A-R-S-M-G-I-T-V-E-G"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-L-P-A-Q-N-K-L-T-S-S-V-Q-F-R-T-T-M-R-K-G-R-R-A-G-S-S-T-V-V-V-H-L-W-D-S-A-E-S-L-D-G-T-G-E-K-G-E-V-A-S-F-G-G-P-R-F-G-L-I-V-S-K-A-V-G-N-A-V-I-R-H-R-T-S-R-R-L-R-H-V-C-A-R-I-A-A-D-S-P-E-L-L-T-P-T-H-H-V-V-I-R-A-L-A-G-S-G-Q-A-S-S-Q-D-L-E-R-D-I-R-H-G-L-R-K-A-G-R-V-R-T-D-K"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-K-V-T-P-D-T-P-G-R-D-D-P-G-P-G-R-R-I-G-L-D-V-G-T-V-R-I-G-V-A-A-S-D-R-D-A-R-L-A-M-P-V-E-T-V-P-R-E-T-G-M-K-G-P-D-R-G-D-I-D-R-L-I-D-I-I-T-E-Y-D-A-V-E-V-V-V-G-L-P-R-D-L-Q-G-N-G-S-A-S-V-K-Q-A-R-E-I-A-F-R-I-R-R-R-L-T-A-T-G-R-E-I-P-V-R-L-G-D-E-R-L-T-T-V-V-A-T-Q-A-L-R-A-S-G-I-N-E-R-D-G-R-K-V-I-D-Q-A-A-A-V-E-I-L-Q-T-W-L-D-G-R-A-T-A-L-N-T-L-P-E-T-P-H-T-D-E-K-G-N-F-P-R"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-T-A-D-F-K-N-G-L-V-L-K-V-D-G-K-L-Q-Q-I-V-E-F-Q-H-V-K-P-G-K-G-P-A-F-V-R-T-K-L-K-D-V-V-T-G-K-T-V-D-K-T-W-N-A-G-V-K-V-E-T-A-T-V-D-R-R-D-M-T-Y-L-Y-N-D-G-S-S-Y-I-L-M-D-D-K-T-F-E-Q-F-E-L-P-L-D-A-F-G-D-A-G-R-F-L-L-E-N-M-R-V-Q-V-S-F-H-D-G-E-A-L-F-G-E-L-P-V-S-V-D-L-R-V-E-H-T-D-P-G-L-Q-G-D-R-S-T-G-G-T-K-P-A-T-L-E-T-G-A-E-I-Q-V-P-L-F-I-E-T-G-N-V-L-K-V-D-T-R-D-G-S-Y-L-S-R-V-N-N"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-E-S-R-Q-G-Y-K-R-H-G-A-R-Y-K-A-R-R-R-A-V-D-I-L-F-E-A-E-S-R-D-V-D-P-V-A-I-I-D-D-R-K-T-L-S-N-A-V-D-P-V-V-A-P-V-A-E-Y-T-E-A-I-I-N-G-V-A-V-E-L-D-T-I-D-D-L-L-S-E-H-I-A-D-T-W-L-L-E-R-L-P-S-V-D-R-A-V-L-R-V-A-C-W-E-M-L-Y-N-P-D-V-P-V-T-T-A-V-V-E-A-V-E-I-A-S-Q-Y-S-T-D-K-A-G-A-Y-I-N-A-T-L-D-N-M-A-S-K-V-D-E-L-R-E-R-A-A-N-P-G-A-V-S-G-S-D-A-P-V-A-P-W-D-D-S-E-E-L-P-A-E-D-E-A-E-D-S-R-P"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-S-E-R-R-N-T-V-V-E-L-L-G-E-N-D-V-S-R-T-V-A-R-I-A-H-Q-I-I-E-K-T-A-L-D-S-E-G-A-D-R-V-M-L-L-G-I-P-S-G-G-V-P-L-A-E-R-L-A-A-K-I-E-E-F-S-G-V-R-V-D-T-G-A-I-D-I-T-L-Y-R-D-D-L-R-N-K-P-H-R-A-L-Q-P-T-S-I-P-S-G-G-I-D-K-T-T-V-V-L-V-D-D-V-L-F-S-G-R-T-V-R-A-A-L-D-A-L-R-D-L-G-R-P-N-Y-I-Q-L-A-V-L-V-D-R-G-H-R-Q-L-P-I-R-A-D-Y-V-G-K-N-L-P-T-A-R-A-E-D-V-T-V-M-L-R-E-I-D-G-R-D-A-V-T-L-T-R-E-E-G-E-G-D-N"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-S-G-D-K-P-H-G-R-L-V-I-L-A-G-P-S-A-V-G-K-S-T-V-V-D-R-L-R-S-D-V-P-N-L-Y-F-S-V-S-M-T-T-R-D-P-R-P-G-E-V-D-G-R-D-Y-F-Y-V-T-A-Q-E-F-Q-E-K-I-D-R-G-E-M-L-E-W-A-D-I-H-G-G-L-Q-R-S-G-T-P-A-E-P-V-R-Q-A-R-E-E-G-R-P-V-L-V-E-V-D-L-V-G-A-R-N-I-A-R-L-I-P-E-A-E-T-I-F-L-A-P-P-S-W-E-V-L-V-E-R-L-T-G-R-G-T-E-S-Q-D-V-I-N-R-R-L-E-T-A-R-E-E-L-A-A-Q-S-E-F-K-H-V-I-I-N-D-D-V-D-T-A-V-S-A-I-K-A-V-L-L-G-T"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-S-V-T-N-V-S-N-E-T-N-A-T-K-A-V-F-D-P-P-M-G-I-T-A-P-P-I-D-E-L-L-D-K-V-T-S-K-Y-A-L-V-I-F-A-A-K-R-A-R-Q-I-N-S-Y-Y-Q-Q-A-D-E-G-V-F-E-F-I-G-P-L-V-T-P-Q-P-G-E-K-P-L-S-I-A-L-R-E-I-N-V-G-L-L-D-H-E-E-G"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-T-V-R-D-V-R-I-F-G-D-P-V-L-T-S-R-A-D-E-V-V-D-F-D-E-S-L-A-T-L-I-D-D-M-F-D-T-M-E-D-A-G-G-V-G-L-A-A-N-Q-V-G-V-L-R-R-V-F-V-F-D-C-S-H-V-D-G-G-L-R-G-H-V-V-N-P-V-W-E-P-I-G-E-E-T-Q-T-G-K-E-G-C-L-S-I-P-D-V-S-A-E-T-T-R-Y-E-T-V-K-L-S-G-Q-D-R-D-G-N-P-I-G-L-V-A-S-G-L-L-S-R-C-I-Q-H-E-T-D-H-L-D-G-V-L-F-L-K-R-L-D-P-A-E-R-K-A-A-M-G-V-I-R-A-S-D-W-F-N-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-A-K-E-G-L-P-E-I-T-L-P-D-A-T-G-L-R-V-A-V-V-T-A-R-W-N-A-E-I-C-D-R-L-H-D-H-A-V-T-A-G-R-A-A-G-A-E-V-S-E-Y-R-V-V-G-A-L-E-L-P-V-V-V-Q-E-L-A-R-T-H-D-A-V-V-A-L-G-C-V-I-R-G-G-T-P-H-F-D-Y-V-C-D-S-V-T-E-G-L-T-R-I-A-L-D-T-S-T-P-I-G-N-G-V-L-T-T-N-T-E-E-Q-A-I-E-R-S-G-A-E-G-S-V-E-D-K-G-A-E-A-M-V-A-A-L-D-T-A-L-V-L-S-R-I-R-A-D-R-G"} +{"text": "### FUNCTION AcnR negatively controls the expression of the aconitase gene acn ### SEQUENCE -M-S-V-A-T-G-D-K-P-V-N-S-R-Q-E-I-L-E-G-A-R-R-C-F-A-E-H-G-Y-E-G-A-T-V-R-R-L-E-E-A-T-G-K-S-R-G-A-I-F-H-H-F-G-D-K-E-K-L-F-L-A-L-A-R-E-D-A-A-R-M-A-E-T-V-S-E-N-G-L-V-E-V-M-R-G-M-L-E-D-P-E-R-Y-D-W-L-S-I-R-L-E-I-S-K-Q-L-R-T-D-P-E-F-R-A-K-W-T-D-H-Q-S-V-L-D-E-A-V-R-V-R-L-A-R-N-A-D-K-G-R-M-R-T-D-V-P-I-E-V-L-H-L-Y-L-E-T-V-M-D-G-F-I-S-R-L-A-T-G-A-S-T-E-G-L-S-E-V-L-D-L-V-E-T-S-V-R-R-P-D"} +{"text": "### FUNCTION Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation The tagging system is termed pupylation ### SEQUENCE -M-S-D-R-Q-T-Q-I-P-A-G-G-G-R-E-D-D-H-D-D-Q-V-Q-S-A-G-Q-V-Q-V-N-T-E-G-V-D-D-L-L-D-E-I-D-G-L-L-E-N-N-A-E-E-F-V-R-S-Y-V-Q-K-G-G-E"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-S-L-G-P-W-E-I-A-I-I-V-L-L-I-I-V-L-F-G-A-K-K-L-P-D-A-A-R-S-I-G-R-S-M-R-I-F-K-S-E-V-K-E-M-Q-K-D-D-E-T-P-A-Q-P-E-Q-Q-P-Q-G-Y-Q-H-P-Q-Q-I-E-A-P-Q-N-L-Q-Q-P-N-F-Q-Q-H-Y-Q-N-Q-P-Q-Q-P-D-Y-R-Q-N-Y-E-D-P-N-R-T-P"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-P-L-V-H-V-M-L-L-S-C-G-V-A-A-D-A-F-A-C-S-I-A-R-G-T-A-I-R-V-N-I-I-K-R-S-L-I-L-A-G-I-F-G-V-F-Q-A-L-M-P-V-I-G-W-G-I-G-Y-F-F-A-E-L-S-F-I-R-A-I-D-H-W-V-A-F-L-L-L-A-G-V-G-A-K-M-I-W-D-A-F-H-Q-D-A-D-V-D-V-I-D-T-G-A-V-Q-L-R-P-A-L-I-L-G-L-A-T-S-I-D-A-L-A-V-G-M-G-M-A-F-V-H-A-P-I-I-T-L-A-L-A-M-G-L-T-T-F-V-L-S-L-V-G-A-W-M-G-H-H-G-G-G-R-F-G-G-W-A-T-V-I-G-G-L-V-L-I-G-L-G-G-N-I-L-F-D-H-M-L-G"} +{"text": "### FUNCTION An essential component of the PknG signaling pathway When unphosphorylated, it inhibits the activity of 2-oxoglutarate dehydrogenase When phosphorylated it does not inhibit 2-oxoglutarate dehydrogenase ### SEQUENCE -M-S-D-N-T-G-T-P-E-P-Q-V-E-T-T-S-V-F-R-A-D-L-L-K-E-M-S-G-A-G-S-A-P-A-A-T-G-A-D-N-L-P-A-G-S-A-L-L-V-V-K-R-G-P-N-A-G-A-R-F-L-L-D-Q-P-T-T-T-A-G-R-H-P-E-S-D-I-F-L-D-D-V-T-V-S-R-R-H-A-E-F-R-I-N-E-G-E-F-E-V-V-D-V-G-S-L-N-G-T-Y-V-N-R-E-P-R-N-S-Q-V-L-Q-T-G-D-E-I-Q-I-G-K-F-R-L-V-F-L-A-G-P-A-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-T-M-D-D-G-R-A-S-T-S-T-P-V-T-R-T-A-R-Q-A-L-I-V-Q-I-L-N-R-Q-R-V-T-S-Q-V-Q-L-S-E-L-L-L-D-E-G-I-D-I-T-Q-A-T-L-S-R-D-L-D-E-L-G-A-R-K-V-R-P-D-R-G-R-A-F-Y-A-I-G-P-V-D-T-T-I-G-E-D-L-R-G-P-Q-E-K-L-R-R-M-L-D-E-L-L-V-S-T-D-H-S-G-N-I-A-M-L-R-T-P-P-G-A-A-Q-Y-L-A-S-F-I-D-R-V-G-L-K-E-V-V-G-T-I-A-G-D-D-T-V-F-V-L-A-R-E-P-L-T-G-R-D-L-G-E-L-L-G-G-R-A-G-A-R-G-P-E-G-K-V"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-S-V-N-A-K-K-K-R-R-E-I-L-K-S-A-K-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-W-L-H-S-M-T-Y-A-Y-R-D-R-R-A-R-K-G-E-F-R-K-L-W-I-Q-R-I-N-A-A-A-R-M-N-G-I-T-Y-N-R-L-I-Q-G-L-R-L-A-E-I-E-V-D-R-K-I-L-A-D-L-A-V-N-D-F-A-A-F-S-A-I-C-E-A-A-K-A-A-L-P-E-D-V-N-A-P-K-A-A-A"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-T-Q-P-D-M-S-Q-I-L-A-Q-A-Q-Q-M-Q-A-Q-L-Q-A-A-Q-Q-E-I-L-A-S-S-V-V-G-D-A-A-N-G-L-V-T-V-T-M-S-G-S-G-E-V-T-A-V-N-I-D-P-K-V-V-D-P-E-D-V-E-T-L-Q-D-L-V-Q-G-A-F-L-D-A-H-K-K-V-A-D-L-A-Q-E-K-M-G-P-L-S-Q-G-F-G-G-D-M-G-S-L-F"} +{"text": "### FUNCTION Involved in cell division ### SEQUENCE -M-P-K-A-K-V-T-K-N-S-I-A-P-V-S-S-N-P-S-A-N-R-T-P-V-K-I-N-S-T-G-T-P-M-W-Y-K-V-I-M-F-A-F-M-L-V-G-L-L-W-L-V-A-N-Y-L-V-G-P-Q-I-P-F-M-N-E-L-D-A-W-N-Y-G-I-G-F-G-L-L-I-I-G-L-L-M-T-M-G-W-R"} +{"text": "### FUNCTION Has a post-transcriptional repressor function in flagellum biogenesis Associates with the 5'-UTR of fljK mRNA and promotes its degradation ### SEQUENCE -M-A-A-N-S-K-T-A-I-R-L-S-L-R-A-G-E-R-I-F-I-N-G-A-V-L-R-A-D-R-K-V-S-L-E-L-L-N-D-A-T-F-L-L-E-N-H-V-L-Q-P-E-D-T-T-T-P-L-R-Q-L-Y-F-A-A-Q-M-M-L-I-E-P-A-M-R-E-Q-A-G-A-T-F-A-Q-M-L-K-G-M-F-A-T-F-K-D-A-E-I-L-N-A-L-K-L-V-D-E-L-V-H-N-G-R-V-F-E-A-L-K-T-I-R-A-Q-Y-P-R-E-A-E-L-M-G-A-Q-P-V-V-W-P-V-T-K-S-G-K-S-A-G-A-N-P"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-S-K-K-Q-I-L-R-L-R-K-R-A-E-F-L-T-V-R-N-G-E-K-R-R-G-P-L-F-L-M-E-V-R-E-R-T-E-E-E-S-N-A-A-K-T-G-D-N-P-R-V-G-F-T-V-T-K-K-N-G-N-A-V-I-R-N-R-I-R-R-R-L-K-E-A-I-R-C-H-A-G-R-D-M-A-P-S-T-D-Y-V-I-V-A-R-E-Q-A-L-N-A-P-F-S-Q-L-T-E-E-L-S-R-R-I-T-A-K-G-E-R-R-S-G-R-K-R-R-T-E-R-P-E-P-G-P-V-N-G-K"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-R-N-W-R-Q-A-E-N-I-R-L-Y-I-A-V-G-C-G-A-A-I-G-A-L-L-R-F-L-S-G-W-V-I-V-A-I-L-G-A-N-P-L-W-G-T-S-F-V-N-I-V-G-S-F-I-I-M-F-F-A-T-L-T-G-P-E-G-R-W-L-V-S-P-A-W-R-Q-F-V-M-G-G-L-C-G-G-L-T-T-F-S-S-M-S-L-D-T-F-L-L-V-L-H-G-N-A-A-F-A-L-A-Y-L-C-G-L-V-F-L-S-L-S-A-A-M-L-G-L-I-A-A-Q-R-I-N-R"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-S-V-E-A-S-I-L-V-L-V-G-G-F-I-G-G-V-M-R-F-F-L-S-G-Y-V-G-R-R-I-G-E-T-F-P-W-G-T-F-V-V-N-V-S-G-A-F-V-I-G-T-A-A-G-L-G-A-R-L-G-A-I-F-S-T-T-I-F-H-E-F-I-M-V-G-L-L-G-G-Y-T-T-V-S-S-F-C-L-Q-S-V-N-L-M-L-D-G-E-Q-R-Q-A-L-F-N-I-V-A-S-A-L-L-C-V-L-A-V-A-A-G-Y-G-G-I-M-W-I-M-E-W-P-G"} +{"text": "### FUNCTION Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose Essential for virulence May be involved in LPS biosynthesis or polysaccharide transport ### SEQUENCE -M-N-S-F-R-K-T-C-A-G-A-L-A-L-I-F-G-A-T-S-I-V-P-T-V-A-A-P-M-N-M-D-R-P-A-I-N-Q-N-V-I-Q-A-R-A-H-Y-R-P-Q-N-Y-N-R-G-H-R-P-G-Y-W-H-G-H-R-G-Y-R-H-Y-R-H-G-Y-R-R-H-N-D-G-W-W-Y-P-L-A-A-F-G-A-G-A-I-I-G-G-A-I-S-Q-P-R-P-V-Y-R-A-P-A-G-S-P-H-V-Q-W-C-Y-S-R-Y-K-S-Y-R-A-S-D-N-T-F-Q-P-Y-N-G-P-R-K-Q-C-R-S-P-Y-S-R"} +{"text": "### FUNCTION Antioxidant protein with alkyl hydroperoxidase activity Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity ### SEQUENCE -M-S-I-D-D-L-K-S-K-I-P-D-F-A-K-D-V-R-L-N-L-S-S-M-A-S-N-E-T-L-T-P-Q-Q-K-Y-G-L-F-V-A-C-G-I-A-S-R-N-A-D-V-R-K-A-L-V-A-E-A-A-G-K-V-D-A-S-V-I-Q-A-A-K-A-A-A-S-I-M-G-M-N-N-V-Y-Y-R-F-V-H-L-A-S-N-K-D-Y-R-T-M-P-A-R-L-R-M-N-V-I-S-N-P-G-V-D-K-V-D-F-E-L-W-S-L-A-V-S-A-I-N-G-C-G-M-C-I-D-A-H-E-D-V-L-R-K-A-N-V-T-A-E-A-I-Q-A-A-V-R-F-A-S-I-I-Q-S-A-A-I-A-L-E-A-A-D-T-E"} +{"text": "### FUNCTION Essential protein that is involved in the control of cell division, probably through the regulation of ctrA Its phosphorylation status is regulated by PdhS ### SEQUENCE -M-T-K-S-V-M-I-V-E-D-N-E-L-N-M-K-L-F-R-D-L-I-E-A-S-G-Y-E-T-I-R-T-R-S-G-L-E-A-L-D-L-A-R-E-H-H-P-D-L-I-L-M-D-I-Q-L-P-E-V-S-G-L-E-V-T-K-W-L-K-D-D-E-E-L-R-H-I-P-V-I-A-V-T-A-F-A-M-K-G-D-E-E-R-I-R-Q-G-G-C-E-A-Y-I-S-K-P-I-S-V-P-R-F-I-E-T-I-K-S-Y-L-G-D-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-T-A-E-I-E-E-I-P-A-L-L-K-P-G-Q-T-V-A-G-L-D-L-G-T-K-T-I-G-L-A-V-S-D-L-G-L-S-F-A-H-P-R-P-V-I-K-R-V-K-F-T-I-D-A-Q-V-L-L-K-A-L-E-T-D-K-V-G-V-I-V-I-G-L-P-M-N-M-D-G-T-A-G-P-R-V-Q-A-T-R-A-F-V-R-T-M-Q-P-L-T-D-L-P-F-V-F-W-D-E-R-L-S-T-V-A-A-E-R-A-L-I-G-M-D-V-S-R-G-K-R-A-D-R-I-D-S-A-A-A-A-F-I-L-Q-G-A-L-D-R-L-H-M-M-R-R-N-D-Y-D-A-G"} +{"text": "### FUNCTION Required for optimal acid stress protection Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins ### SEQUENCE -M-I-K-A-L-F-N-K-N-T-A-L-A-A-V-T-I-L-A-L-S-G-G-A-M-A-E-S-A-K-T-H-K-T-D-M-A-K-K-K-V-S-E-L-T-C-E-D-F-N-G-L-E-E-S-F-K-P-T-V-V-G-W-V-V-G-F-N-K-K-G-K-E-E-D-A-V-I-D-V-D-G-I-E-T-V-T-P-A-I-I-E-A-C-K-Q-E-P-K-A-S-F-W-K-K-A-E-A-E-L-K-K-V-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-I-T-A-E-R-K-Q-A-L-I-K-E-Y-A-T-K-E-G-D-T-G-S-P-E-V-Q-V-A-V-L-S-E-R-I-A-N-L-T-E-H-F-K-G-H-K-N-D-N-H-S-R-R-G-L-L-K-L-V-S-Q-R-R-R-L-L-D-Y-V-K-G-V-D-H-A-R-Y-Q-A-L-I-T-R-L-G-L-R-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-R-S-H-D-T-K-G-S-G-G-L-S-Q-R-Q-L-R-V-G-E-Q-V-R-H-A-L-A-Q-V-L-Q-R-G-E-I-R-D-D-L-I-E-R-T-V-I-S-V-S-E-V-R-M-S-P-D-L-K-I-A-T-C-F-I-T-P-L-G-S-A-D-P-Q-A-V-I-K-A-L-A-S-H-A-K-F-I-R-G-R-V-A-P-S-L-A-Q-M-K-Y-M-P-E-F-R-F-R-P-D-T-S-F-D-N-F-S-K-I-D-A-L-L-R-S-P-E-V-A-R-D-L-S-H-D-D-D-E-D-G-G-A-D-E-A-P-R-N-G-D-E"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-D-K-A-A-G-E-T-K-N-G-N-G-A-T-T-E-P-S-L-N-I-L-A-Q-Y-V-K-D-L-S-F-E-S-P-G-A-P-L-S-L-R-P-R-E-K-A-P-S-I-N-I-N-V-N-V-N-A-N-P-L-S-E-T-D-F-D-V-V-L-T-L-E-A-K-A-V-D-G-K-D-I-L-F-N-T-E-L-V-Y-G-G-V-F-R-I-Q-G-I-P-Q-E-H-M-L-P-L-L-F-I-E-C-P-R-L-L-F-P-F-A-R-Q-I-I-A-D-A-T-R-N-G-G-Y-P-P-L-M-I-D-P-I-D-F-A-Q-M-F-Q-Q-R-M-A-E-E-Q-A-K-S-A-V-K-S"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-T-V-K-L-V-L-A-S-K-S-P-F-R-S-A-L-L-K-N-A-G-I-E-F-S-T-A-S-A-D-I-D-E-R-A-V-E-A-P-L-Y-E-S-G-A-T-P-E-D-V-A-Q-I-L-A-E-A-K-A-I-D-V-S-E-K-N-P-G-A-V-V-I-G-C-D-Q-T-L-S-L-G-D-E-I-F-H-K-P-H-D-M-E-A-A-R-R-Q-L-Q-K-F-S-G-K-T-H-Q-L-N-S-A-V-V-L-A-R-D-G-K-T-L-W-R-H-V-S-I-A-H-M-T-M-R-D-L-D-A-G-F-I-G-R-Y-L-G-R-V-G-D-I-A-L-S-S-V-G-A-Y-Q-V-E-G-P-G-I-Q-L-F-E-K-I-D-G-D-Y-F-T-I-V-G-L-P-L-L-P-L-L-A-E-L-R-R-E-K-C-I-D-G"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-I-K-T-G-G-K-Q-Y-R-V-A-A-N-D-L-I-K-V-E-K-V-A-G-E-A-G-D-I-V-E-F-A-E-V-L-M-V-G-S-T-I-G-A-P-T-V-A-G-A-L-V-T-A-E-V-V-E-Q-G-R-G-R-K-V-I-A-F-K-K-R-R-R-Q-N-S-K-R-T-R-G-H-R-Q-E-L-T-T-I-R-I-S-E-I-L-T-D-G-A-K-P-S-K-K-A-A-E-K-K-A-P-K-A-D-A-A-E-G-E-A-A-K-P-K-K-A-A-P-K-K-A-A-A-K-A-E-S-A-E"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-S-K-H-K-G-P-T-G-A-M-V-D-P-E-S-L-P-Y-R-P-C-V-G-L-M-V-L-N-K-A-G-L-V-W-A-G-R-R-I-V-I-P-G-D-E-M-D-G-A-T-Q-L-W-Q-M-P-Q-G-G-I-D-K-G-E-D-P-A-Q-A-A-L-R-E-L-Y-E-E-T-G-M-T-S-V-S-L-L-E-E-A-S-D-W-I-N-Y-D-L-P-P-H-L-V-G-L-A-L-K-G-K-Y-R-G-Q-T-Q-K-W-F-A-Y-R-F-E-G-D-E-S-E-I-A-I-N-P-P-P-G-G-H-T-A-E-F-D-C-W-E-W-K-P-M-A-D-L-P-N-L-I-V-P-F-K-R-K-V-Y-E-Q-V-V-A-T-F-R-H-L-A-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-T-S-S-L-I-S-G-V-A-Q-R-Y-A-G-S-L-F-E-L-A-L-D-A-N-S-V-A-S-V-E-K-D-L-G-R-F-E-A-L-L-S-G-S-K-D-L-R-R-L-I-S-S-P-V-F-S-S-E-D-Q-L-H-A-I-G-A-I-A-D-K-A-G-I-K-G-L-V-G-N-F-L-R-V-V-A-Q-N-R-R-L-F-A-L-P-G-I-I-A-A-F-R-Q-I-A-A-E-H-R-G-E-I-S-A-D-V-V-S-A-H-E-L-T-S-A-Q-Q-N-E-L-K-A-T-L-K-G-V-A-G-K-D-V-T-I-N-V-T-V-D-P-S-I-L-G-G-L-I-V-K-M-G-S-R-Q-I-D-T-S-L-R-T-K-L-S-S-L-K-L-A-L-K-E-V-G"} +{"text": "### FUNCTION Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide ### SEQUENCE -M-S-V-D-V-A-I-I-M-G-S-Q-S-D-W-E-T-M-R-H-A-A-H-T-L-E-A-L-G-I-S-F-D-A-R-I-V-S-A-H-R-T-P-D-R-L-V-A-F-A-K-G-A-K-A-E-G-F-K-V-I-I-A-G-A-G-G-A-A-H-L-P-G-M-A-A-A-M-T-P-L-P-V-F-G-V-P-V-Q-S-K-A-L-S-G-Q-D-S-L-L-S-I-V-Q-M-P-A-G-I-P-V-G-T-L-A-I-G-R-A-G-A-V-N-A-A-L-L-A-A-A-V-L-A-L-Y-D-E-A-L-A-A-R-L-D-E-W-R-K-A-Q-T-E-S-V-A-E-R-P-S-N-E-A"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-I-N-G-N-E-I-R-P-G-N-V-I-E-H-E-G-G-L-W-V-A-V-K-T-N-A-V-K-P-G-K-G-G-A-Y-N-Q-V-E-L-K-N-L-I-N-G-T-K-L-N-E-R-F-R-A-A-E-T-V-E-R-V-R-L-E-Q-K-D-F-S-F-L-Y-E-Q-G-E-A-L-I-F-M-D-T-E-T-Y-E-Q-L-E-L-Q-K-D-F-V-G-D-R-A-A-F-L-Q-D-G-M-M-V-T-V-E-L-Y-E-E-K-P-I-G-I-R-L-P-D-Q-V-T-L-A-I-T-E-A-D-P-V-V-K-G-Q-T-A-A-S-S-Y-K-P-A-V-L-E-N-G-I-R-I-L-V-P-P-F-I-A-S-G-E-R-V-I-V-D-T-N-E-L-T-Y-I-S-R-A"} +{"text": "### FUNCTION Acts as a global negative controlling element, employing Fe as a cofactor to bind the operator of the repressed genes ### SEQUENCE -M-N-K-P-Y-T-K-P-D-Y-E-Q-E-L-R-R-A-G-V-R-I-T-R-P-R-R-I-I-L-N-I-L-N-E-T-E-D-H-P-D-A-L-E-I-F-R-R-A-V-E-E-D-D-S-I-S-L-S-T-V-Y-R-T-I-K-L-L-E-E-R-G-A-I-H-R-H-A-F-A-G-G-P-S-R-F-E-Q-A-S-G-A-H-H-D-H-I-I-D-M-D-S-G-D-V-V-E-F-H-S-D-K-I-E-K-L-Q-E-E-I-A-R-S-L-G-F-E-I-V-H-H-R-L-E-L-Y-C-K-K-L-K-S"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-T-P-L-D-V-M-W-V-G-L-G-G-G-V-G-S-L-G-R-W-W-I-G-R-I-V-G-E-Y-H-H-G-A-F-P-L-G-T-F-L-I-N-I-S-G-A-F-V-I-G-Y-L-S-V-L-F-G-V-D-W-H-D-R-Y-G-T-M-L-N-A-G-V-L-T-G-I-L-G-G-Y-T-T-F-S-S-M-Q-L-D-A-V-K-L-S-H-K-G-Q-G-G-L-A-V-F-Y-L-V-A-S-V-L-S-G-L-F-A-A-W-L-D-A-M-L-A-H-L-Q-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-A-G-Q-L-K-L-Q-V-P-A-G-A-A-N-P-S-P-P-I-G-P-A-L-G-Q-R-G-I-N-I-M-E-F-C-K-A-F-N-A-A-S-Q-E-M-E-K-G-S-P-I-P-V-L-I-T-Y-Y-Q-D-K-S-F-T-F-V-M-K-T-P-P-V-T-Y-F-L-K-K-A-A-N-L-K-S-G-S-K-T-P-G-K-A-S-A-G-T-I-T-R-D-K-V-R-A-I-A-E-A-K-M-K-D-L-N-A-A-D-V-E-A-A-M-R-M-I-E-G-S-A-R-S-M-G-L-E-V-V-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-D-R-A-E-K-R-E-F-V-A-W-L-N-G-A-F-K-E-S-G-S-V-V-V-A-H-Y-T-G-L-T-V-A-Q-M-S-D-L-R-S-K-M-R-D-A-G-G-S-V-K-V-A-K-N-R-L-A-K-I-A-L-Q-G-T-E-S-E-G-I-A-D-L-F-T-G-Q-T-V-V-A-Y-A-N-D-P-I-T-A-P-K-V-A-V-E-F-A-K-A-N-D-K-L-V-I-L-G-G-A-M-G-A-T-T-L-N-A-D-G-V-K-S-L-A-S-L-P-S-L-D-E-L-R-A-K-L-V-G-M-I-Q-T-P-A-Q-R-L-A-V-L-T-S-A-P-A-S-Q-I-A-R-V-I-G-A-H-A-R-K-N-E-A-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-K-A-E-K-R-E-I-N-P-D-P-K-F-G-D-L-V-I-T-K-F-M-N-A-V-M-L-H-G-K-K-S-V-A-E-S-I-V-Y-G-A-L-D-A-I-E-A-K-A-K-S-E-P-V-A-L-F-H-Q-A-L-D-N-V-A-P-H-I-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-D-V-R-P-E-R-R-Q-A-L-A-I-R-W-L-I-N-A-A-R-G-R-N-E-T-T-M-V-D-R-L-S-G-E-L-L-D-A-A-N-N-R-G-S-A-V-K-K-R-E-D-T-H-R-M-A-E-A-N-R-A-F-S-H-Y-R-W"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-D-L-R-H-Y-D-V-I-V-S-P-V-I-T-E-K-S-T-M-V-S-E-H-N-Q-V-V-F-N-V-A-R-K-A-T-K-P-E-I-K-A-A-V-E-A-L-F-G-V-K-V-T-A-V-N-T-A-V-R-K-G-K-V-K-R-F-R-G-L-V-G-R-Q-S-D-V-K-K-A-I-V-T-L-A-E-G-Q-S-I-D-V-S-T-G-L"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-G-K-A-K-A-P-R-Q-L-K-D-N-E-A-K-A-V-A-R-T-L-R-V-S-P-Q-K-L-N-L-V-A-S-M-I-R-G-K-K-V-N-A-A-L-A-D-L-T-F-S-R-K-R-I-A-G-T-V-K-K-T-L-E-S-A-I-A-N-A-E-N-N-H-D-L-D-V-D-A-L-I-V-A-E-A-Y-V-G-K-S-I-V-M-K-R-F-H-V-R-G-R-G-R-A-S-R-I-E-K-P-F-S-H-L-T-I-V-V-R-E-V-A-E-K-G-E-A-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-M-Q-P-K-R-T-K-F-R-K-Q-F-K-G-R-I-H-G-N-S-K-G-G-T-D-L-N-F-G-A-F-G-L-K-A-L-E-P-E-R-V-T-A-R-Q-I-E-A-A-R-R-A-I-T-R-H-M-K-R-A-G-R-V-W-I-R-I-F-P-D-L-P-V-T-S-K-P-T-E-V-R-M-G-K-G-K-G-S-V-D-Y-W-A-C-R-V-A-P-G-R-V-M-F-E-L-D-G-V-P-E-D-V-A-R-E-A-L-R-L-G-A-A-K-L-P-I-K-T-R-F-I-Q-R-I-A-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-V-L-Q-G-V-V-V-S-D-K-N-D-K-T-V-V-V-K-V-E-R-R-Y-S-H-P-L-L-Q-K-T-V-R-Q-S-K-K-Y-K-A-H-D-E-N-N-Q-F-K-V-G-D-F-V-S-I-Q-E-S-A-P-I-S-K-D-K-R-W-V-V-L-T-S-E-A-A-G"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-N-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-S-V-G-D-I-I-V-V-S-I-K-E-A-I-P-R-G-R-V-K-K-G-D-V-M-K-A-V-V-V-R-T-A-K-D-I-R-R-P-D-G-S-V-I-R-F-D-N-N-A-A-V-L-I-D-N-K-K-E-P-I-G-T-R-I-F-G-P-V-P-R-E-L-R-A-K-N-H-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-K-I-R-K-G-D-S-V-V-V-L-S-G-K-D-K-G-R-K-G-E-V-L-K-V-M-P-K-D-E-Q-A-L-V-S-G-I-N-I-V-K-R-H-Q-R-Q-T-Q-T-Q-E-A-G-I-I-S-K-E-A-P-I-H-L-S-N-L-A-I-A-D-P-K-D-G-K-P-T-R-V-G-F-R-V-E-D-G-K-K-V-R-V-A-K-R-S-G-A-L-I-D-G"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-E-A-K-A-L-P-R-F-K-K-L-Y-Q-D-N-I-R-K-A-L-L-E-E-F-K-Y-D-N-E-M-Q-I-P-R-I-T-K-V-V-L-N-M-G-V-G-E-A-T-G-D-S-K-K-P-A-V-A-A-E-D-L-A-M-I-A-G-Q-K-A-V-V-T-R-A-R-N-S-I-A-T-F-K-L-R-E-G-M-P-I-G-A-K-V-T-L-R-Q-D-R-M-Y-E-F-L-D-R-L-I-T-I-A-L-P-R-V-R-D-F-R-G-L-N-P-K-S-F-D-G-R-G-N-Y-A-M-G-I-K-E-H-I-V-F-P-E-I-N-Y-D-K-V-D-Q-I-W-G-M-D-I-I-V-C-T-T-A-K-T-D-D-E-A-R-S-L-L-R-A-F-N-F-P-F-R-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-V-S-D-P-L-G-D-M-L-T-R-I-R-N-A-V-G-R-K-K-T-K-V-S-T-P-A-S-K-L-R-A-R-V-L-D-V-L-Q-A-E-G-Y-I-R-G-Y-T-Q-S-E-F-E-N-G-K-A-E-I-E-I-E-L-K-Y-Y-E-G-V-P-V-I-R-E-I-T-R-V-S-K-P-G-R-R-V-Y-V-S-V-K-S-I-P-Q-V-A-N-G-L-G-I-S-I-L-S-T-P-K-G-V-M-A-D-H-E-A-R-E-Q-N-V-G-G-E-L-L-C-R-I-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-P-V-P-V-P-A-G-V-T-A-S-V-E-G-Q-T-V-K-A-K-G-A-K-G-E-L-S-F-V-V-H-D-E-V-L-V-K-M-E-D-G-A-V-R-V-D-P-R-D-Q-S-K-E-A-R-S-K-W-G-M-S-R-T-M-I-S-N-I-F-V-G-V-K-D-G-F-E-K-K-L-E-I-S-G-V-G-Y-R-A-A-M-Q-G-K-N-L-Q-L-S-L-G-F-S-H-E-V-V-Y-D-V-P-A-G-I-T-V-A-V-P-K-P-T-E-I-V-V-T-G-I-D-K-Q-Q-V-G-Q-V-A-A-E-I-R-E-Y-R-G-P-E-P-Y-K-G-K-G-V-K-Y-A-G-E-K-I-V-R-K-E-G-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-S-P-K-E-T-L-Q-R-R-A-A-R-V-R-R-Q-V-K-A-V-A-N-G-R-P-R-L-S-V-H-R-S-S-K-N-I-Y-A-Q-I-I-D-D-V-R-G-V-T-L-A-A-A-S-T-L-D-G-D-L-K-G-K-L-K-T-G-A-D-S-A-A-A-A-A-V-G-K-L-V-A-E-R-A-V-K-A-G-V-K-D-V-V-F-D-R-S-A-F-I-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-G-G-L-S-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-D-L-R-D-K-P-G-S-V-K-A-R-K-R-V-G-R-G-I-G-S-G-T-G-K-T-G-G-R-G-V-K-G-Q-K-S-R-S-G-V-S-I-N-G-F-E-G-G-Q-M-P-I-Y-R-R-L-P-K-R-G-F-T-N-I-F-A-K-S-F-N-V-V-S-L-G-R-I-Q-A-A-I-D-A-G-K-L-D-A-K-A-V-V-N-L-D-S-L-K-A-A-G-V-I-R-R-A-K-D-G-V-R-I-L-S-D-G-E-L-K-A-K-V-A-F-E-V-A-G-A-S-K-A-A-V-E-K-I-E-K-A-G-G-S-I-K-L-P-E-A-A-A-E"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-R-R-I-N-T-I-M-Q-G-K-T-N-G-G-N-G-P-E-S-G-T-V-V-V-T-R-T-Q-P-K-T-R-K-P-S-L-Y-R-V-L-L-L-N-D-D-Y-T-P-M-E-F-V-V-H-V-L-Q-R-F-F-Q-K-N-L-D-D-A-T-R-I-M-L-H-V-H-N-H-G-V-G-E-C-G-V-F-T-Y-E-V-A-E-T-K-V-S-Q-V-M-D-F-A-R-Q-N-Q-H-P-L-Q-C-V-M-E-K-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-D-A-F-D-I-N-D-L-K-R-R-M-E-G-A-V-N-A-L-K-H-D-L-G-G-L-R-T-G-R-A-S-A-S-L-L-E-P-I-T-I-E-A-Y-G-S-T-M-P-I-N-Q-V-A-N-I-S-V-P-E-S-R-M-L-S-V-S-V-W-D-K-S-M-V-G-A-V-E-R-A-I-R-D-S-G-L-G-L-N-P-I-T-D-G-M-T-L-R-I-P-L-P-E-L-N-E-Q-R-R-K-E-L-V-K-I-A-H-Q-Y-A-E-Q-G-R-I-A-A-R-H-V-R-R-D-G-M-D-Q-L-K-K-L-E-K-D-S-V-I-S-Q-D-E-S-R-V-L-S-E-K-V-Q-K-L-T-D-D-T-I-A-E-M-D-K-I-V-A-V-K-E-G-E-I-M-Q-V"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-S-D-D-N-Q-T-K-L-E-A-A-D-I-Q-A-L-L-A-V-L-P-H-R-Y-P-F-L-L-I-D-R-I-V-D-I-D-G-D-V-S-A-T-G-I-K-N-V-T-I-N-E-P-H-F-T-G-H-F-P-E-N-P-I-M-P-G-V-L-I-V-E-A-M-A-Q-T-A-G-A-I-S-L-L-Q-R-K-T-G-R-P-G-V-V-Y-F-M-T-I-D-N-A-K-F-R-R-P-V-V-P-G-D-R-L-L-L-H-V-K-K-I-K-Q-R-A-N-I-S-K-Y-E-C-V-A-E-V-D-G-V-K-V-A-E-A-E-V-A-A-M-I-S-V-A-D-E-N-L"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-V-N-K-V-I-L-V-G-N-L-G-A-D-P-E-I-R-R-L-N-S-G-D-M-V-A-N-L-R-I-A-T-S-E-S-W-R-D-R-Q-T-G-E-R-K-D-R-T-E-W-H-S-V-V-I-F-N-E-N-L-A-K-V-A-E-Q-Y-L-K-K-G-A-K-V-Y-I-E-G-A-L-Q-T-R-K-W-Q-D-Q-N-G-N-D-R-Y-S-T-E-I-V-L-Q-K-F-R-G-E-L-Q-M-L-D-S-R-S-E-G-G-E-G-R-S-F-G-G-G-G-N-R-N-Q-M-S-D-Y-S-G-G-G-G-D-F-G-S-S-G-P-S-S-G-S-S-G-G-F-S-R-D-L-D-D-E-I-P-F"} +{"text": "### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-S-F-I-R-S-A-L-A-A-A-A-F-V-A-L-S-I-G-A-V-Q-T-A-S-A-A-D-P-E-N-T-V-I-L-K-L-K-D-G-D-V-A-L-E-L-R-P-D-L-A-P-K-H-V-A-Q-I-K-K-L-V-R-E-G-A-Y-N-G-V-A-F-H-R-V-I-P-G-F-M-A-Q-T-G-D-V-K-F-G-N-M-D-K-G-F-D-A-A-R-V-G-T-G-G-S-N-Y-P-D-L-P-A-E-F-S-K-E-P-F-V-R-G-T-V-G-M-A-R-S-Q-N-P-N-S-A-N-S-Q-F-F-I-M-F-D-D-G-P-F-L-N-G-Q-Y-T-V-V-G-K-V-V-S-G-M-D-A-V-D-K-I-K-K-G-S-E-A-E-N-G-A-V-K-N-P-D-K-I-I-K-A-T-I-E-A-D-T-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-A-T-F-S-Q-K-P-A-E-V-V-K-K-W-V-L-I-D-A-E-G-L-V-V-G-R-L-A-S-L-V-A-N-R-L-R-G-K-H-K-A-T-F-T-P-H-V-D-D-G-D-N-V-I-I-I-N-A-D-K-V-V-L-T-G-K-K-Y-T-D-K-K-Y-Y-W-H-T-G-H-P-G-G-I-K-E-R-T-A-R-Q-I-L-E-G-R-F-P-E-R-V-L-E-K-A-I-E-R-M-I-P-R-G-P-L-G-R-R-Q-M-K-N-L-R-V-Y-A-G-P-N-H-Q-H-E-A-Q-Q-P-E-V-L-D-V-A-A-L-N-R-K-N-K-G-N-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-N-S-I-P-E-G-R-P-T-P-N-L-P-R-T-A-N-K-R-G-V-A-R-L-A-A-V-Q-A-L-Y-Q-M-D-V-A-G-T-G-V-M-E-V-V-A-E-Y-E-A-F-R-L-G-K-E-V-D-G-T-Q-Y-L-D-A-D-P-Q-W-F-R-A-I-V-A-G-V-V-E-D-Q-L-K-L-D-P-M-I-H-Q-A-L-T-E-D-W-P-L-S-R-L-D-S-T-L-R-A-I-L-R-A-G-A-W-E-L-K-A-R-K-D-V-P-T-A-V-I-V-S-E-Y-V-D-I-A-K-A-F-Y-T-E-D-E-P-K-L-V-N-A-V-L-D-R-L-A-L-V-I-R-G-E-S-R-G-A-K-P-R-H-K-S"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-C-V-D-K-V-E-N-R-F-E-L-V-L-L-A-G-H-R-A-R-Q-I-S-Q-G-V-P-I-T-V-D-R-D-N-D-K-N-P-V-V-A-L-R-E-I-A-D-E-T-L-S-P-D-D-L-K-E-D-L-I-H-S-L-Q-K-H-V-E-V-D-E-P-E-A-A-P-A-Q-I-A-N-A-A-E-E-I-A-E-G-I-A-E-A-G-E-E-D-V-V-T-F-D-R-M-S-E-E-E-L-L-A-G-I-E-G-L-V-A-P-E-K-N-D-G-F"} +{"text": "### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-I-G-M-E-P-L-R-R-R-E-L-I-D-A-A-I-R-T-I-G-Q-R-G-S-L-D-V-T-V-A-Q-I-A-H-E-A-G-V-S-P-A-L-A-H-H-Y-F-G-G-K-D-K-L-I-L-A-T-M-R-H-L-L-R-E-L-G-R-D-L-N-A-A-I-K-Q-A-N-A-P-H-E-R-I-A-A-I-I-A-V-N-F-S-A-A-Q-F-A-Q-E-T-I-A-A-W-L-T-F-Y-V-H-A-Q-Q-S-D-D-I-K-R-L-L-R-I-Y-A-R-R-L-H-S-N-L-V-F-A-L-E-Q-L-T-S-R-A-R-A-N-R-I-A-E-G-A-G-A-M-I-D-G-L-Y-I-R-H-A-L-G-A-D-A-P-D-A-A-S-A-I-A-L-V-E-D-Y-I-A-I-Q-L-S-G-Q-P-S-A-E-N"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 5-hydroxyisourate ### SEQUENCE -M-G-K-L-S-T-H-V-L-D-T-A-H-G-T-P-A-A-A-M-R-V-E-L-Y-R-I-A-A-S-G-T-P-E-L-L-K-R-V-V-T-N-L-D-G-R-T-D-A-P-L-L-S-G-D-K-M-R-T-G-I-Y-E-L-Q-F-H-V-A-E-Y-F-E-G-R-G-A-E-L-A-H-E-P-F-L-D-L-I-P-I-R-F-G-I-A-D-E-D-G-N-Y-H-V-P-L-L-V-S-P-W-S-Y-S-T-Y-R-G-S"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-L-Y-E-H-V-L-L-A-R-Q-D-I-S-Q-Q-Q-V-D-A-L-V-E-Q-F-K-G-V-L-E-A-N-G-G-K-F-G-K-V-E-N-W-G-L-R-P-L-T-Y-R-I-K-K-N-R-K-A-Y-Y-T-L-V-N-I-D-A-P-A-A-A-V-A-E-M-E-R-Q-M-R-I-N-E-D-V-L-R-F-L-T-V-R-V-E-E-H-E-E-G-Q-S-A-M-L-T-R-R-D-D-R-R-E-R-D-G-D-D-R-P-R-R-R-E-G-G-F-D-R-G-D-R-G-D-R-G-P-R-R-P-R-D-T-E-A-G-E-G-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-V-I-L-L-E-R-I-G-R-L-G-Q-M-G-D-T-V-K-V-K-D-G-Y-A-R-N-F-L-L-P-Q-G-K-A-L-R-A-N-E-A-N-K-K-K-F-E-G-Q-R-A-Q-L-E-A-Q-N-L-E-R-K-N-E-A-Q-A-V-A-D-K-L-N-G-E-S-F-I-V-V-R-S-A-G-E-T-G-Q-L-Y-G-S-V-S-T-R-D-I-A-E-I-I-T-A-D-G-F-T-L-H-R-N-Q-V-E-L-N-H-P-I-K-T-I-G-L-H-E-V-S-V-S-L-H-P-E-V-Q-V-K-V-M-V-N-I-A-R-S-T-E-E-A-E-R-Q-A-K-G-E-D-L-T-S-I-E-A-I-Y-G-I-E-E-Q-P-L-S-E-E-V-F-D-D-E-D-E-A-E-D-Q-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-A-T-F-W-A-F-I-A-L-V-I-F-V-V-I-V-V-Y-M-K-V-P-G-M-I-G-R-T-L-D-E-R-A-D-R-I-K-K-E-L-E-E-A-R-T-L-R-E-E-A-Q-Q-L-L-A-E-Y-H-R-K-R-K-E-A-E-K-E-A-G-D-I-V-A-S-A-E-R-E-A-K-A-L-L-E-E-A-K-R-A-T-E-E-Y-V-A-R-R-N-K-L-A-E-Q-K-I-A-T-A-E-T-D-A-I-N-A-V-R-A-S-A-V-D-L-A-V-A-A-A-G-S-I-L-A-E-K-V-D-A-K-A-A-G-N-L-F-N-D-A-L-A-Q-V-K-S-H-L-N"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-Q-E-F-A-L-K-G-N-M-V-D-L-A-I-G-V-I-I-G-G-A-F-G-G-L-V-N-S-I-V-N-D-I-I-M-P-I-I-G-L-I-T-G-G-I-D-F-S-N-M-F-I-Q-L-A-G-D-P-K-T-T-L-A-A-A-R-E-A-G-A-T-I-A-Y-G-N-F-I-T-L-L-I-N-F-L-I-I-A-W-V-L-F-L-V-V-K-L-M-N-R-L-K-K-R-E-E-A-K-P-A-P-A-A-P-S-E-E-V-L-L-T-E-I-R-D-I-L-A-K-Q-Q-K-A"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-V-L-E-F-P-G-V-V-T-E-L-L-P-N-A-M-F-R-V-K-L-E-N-E-H-E-I-I-A-H-T-A-G-R-M-R-K-N-R-I-R-V-L-A-G-D-K-V-L-V-E-M-T-P-Y-D-L-T-K-G-R-I-T-Y-R-L-K"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-I-K-S-E-L-V-Q-I-I-A-S-R-N-P-H-L-F-Q-R-D-V-E-N-I-V-G-A-V-F-D-E-I-T-N-A-L-A-E-G-N-R-V-E-L-R-G-F-G-A-F-S-V-K-N-R-P-A-R-S-G-R-N-P-R-T-G-E-T-V-D-V-E-E-K-W-V-P-F-F-K-T-G-K-E-L-R-D-R-L-N-G-A-V"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-F-G-T-D-P-T-P-D-G-L-A-N-P-P-I-D-D-L-M-K-H-A-D-S-K-Y-A-L-A-I-F-A-A-K-R-A-R-Q-I-N-S-Y-F-T-Q-L-N-E-G-L-L-Q-N-I-G-P-L-V-E-Y-Q-N-N-E-K-P-L-S-I-A-F-R-E-I-D-E-G-L-L-E-E-T-L-G-E-D-D-A-N-E-G-N"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-Q-Q-G-I-H-P-D-Y-H-P-V-E-V-T-C-S-C-G-N-T-F-V-T-R-T-A-G-K-E-D-H-M-F-V-D-V-C-S-Q-C-H-P-F-Y-T-G-K-Q-K-I-L-D-T-G-G-R-V-A-R-F-E-K-R-Y-G-K-K-S-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-G-T-N-P-R-A-A-R-I-A-A-L-I-Q-R-V-V-A-S-S-I-E-R-E-L-H-D-K-R-L-A-S-I-T-V-T-E-V-R-V-T-N-D-L-Q-I-A-K-V-Y-W-T-Q-L-G-H-E-G-H-E-E-G-E-R-K-R-A-Q-Q-A-L-D-Q-A-K-G-H-L-R-S-L-V-G-H-K-A-G-L-R-L-T-P-Q-L-Q-F-V-F-D-E-V-P-G-E-A-H-E-I-E-D-I-L-A-V-A-K-K-R-D-E-E-L-A-R-A-R-A-T-A-Q-Y-A-G-D-A-D-P-Y-K-H-D-D-E-P-S-D-D-F-E-D-D-S-D-E-E"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-L-A-G-V-D-I-P-N-E-K-R-I-E-I-A-L-T-Y-I-F-G-V-G-R-T-R-A-K-E-T-L-A-A-T-G-I-S-P-D-I-R-V-K-D-L-T-D-E-Q-L-I-T-L-R-D-Y-L-E-A-N-Y-K-I-E-G-D-L-R-R-E-V-D-A-D-I-R-R-K-I-Q-I-N-C-Y-Q-G-Q-R-H-R-K-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-K-R-T-V-A-G-K-K-K-A-T-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-G-V-I-E-V-E-G-Q-V-V-E-A-L-P-N-A-M-F-R-V-E-L-E-N-K-H-I-V-L-A-T-I-S-G-K-M-R-K-N-Y-I-R-I-L-P-Q-D-R-V-V-L-E-M-S-P-Y-D-L-N-R-G-R-I-T-Y-R-Y-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-D-N-E-I-L-Q-M-H-D-L-K-P-A-P-G-A-K-K-D-R-T-R-V-G-R-G-E-G-S-K-G-K-T-S-G-R-G-A-K-G-Q-T-K-R-N-H-V-R-P-G-F-E-G-G-Q-L-P-L-Y-M-R-L-P-K-L-R-G-F-K-N-P-F-K-V-E-F-Q-V-I-N-I-A-R-L-V-E-L-F-P-E-G-G-E-V-A-V-A-D-L-I-A-K-G-A-V-R-D-N-A-P-V-K-V-L-G-D-G-E-T-T-V-A-F-T-L-K-G-V-K-A-S-A-S-A-K-S-K-I-E-A-A-G-G-S-V-S-E-D"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-V-A-I-L-G-K-G-K-K-V-A-L-K-R-R-H-A-R-I-R-K-R-I-S-G-T-P-E-R-P-R-L-V-V-T-R-S-N-R-H-M-V-A-Q-V-V-D-D-T-K-G-I-T-L-V-S-A-S-T-L-Q-A-D-F-A-G-F-E-G-T-K-T-E-A-A-K-K-V-G-E-L-I-A-E-K-A-K-A-A-G-I-T-A-V-V-F-D-R-G-G-N-K-Y-T-G-R-V-A-A-V-A-D-G-A-R-E-G-G-L-A-L"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-A-S-H-I-G-K-L-P-I-A-I-P-A-G-V-E-V-K-I-E-G-Q-N-F-S-A-K-G-A-K-G-S-D-S-Y-V-V-P-E-G-I-T-A-A-V-E-G-N-E-I-V-L-T-A-A-D-D-L-R-P-T-R-A-K-H-G-L-A-R-S-I-M-A-G-M-V-K-G-V-H-D-G-Y-S-K-T-L-E-I-V-G-T-G-Y-R-A-V-A-K-G-Q-G-I-E-F-F-L-G-Y-S-H-T-I-T-V-N-P-P-E-G-I-T-L-K-V-T-D-A-N-H-V-V-V-E-G-T-D-K-Q-V-V-G-Q-V-A-A-N-I-R-K-L-R-A-P-E-P-Y-K-G-K-G-I-K-Y-S-D-E-R-I-L-R-K-A-G-K-A-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-I-A-D-M-L-T-R-L-R-N-A-S-A-A-K-H-E-T-V-D-M-P-Y-S-K-F-K-A-N-I-A-E-I-L-K-R-E-G-Y-I-K-D-F-T-A-K-E-A-K-V-G-Q-T-L-E-V-T-L-K-Y-G-P-N-G-E-R-S-I-Q-G-I-K-R-I-S-K-P-G-L-R-R-Y-A-K-S-D-S-L-P-M-P-L-G-G-L-G-I-A-I-I-S-T-S-S-G-L-L-T-Q-K-E-C-L-D-R-G-I-G-G-E-I-V-A-F-V-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-A-L-K-N-K-A-A-G-K-P-K-F-K-V-R-A-Y-T-R-C-Q-V-C-G-R-P-H-S-V-Y-R-K-F-G-L-C-R-I-C-L-R-E-K-A-H-R-G-E-L-P-G-V-T-K-S-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-D-T-T-V-E-A-P-A-T-P-R-L-K-V-K-Y-N-E-Q-I-I-P-E-L-E-K-E-F-K-Y-S-N-P-M-Q-V-A-R-V-Q-K-V-V-V-S-M-G-V-G-A-A-A-R-D-S-K-L-I-E-G-A-V-K-D-L-T-L-I-T-G-Q-K-P-K-I-T-K-A-K-K-S-V-A-Q-F-H-L-R-E-G-Q-A-I-G-A-Y-V-T-L-R-G-D-R-M-W-E-F-L-D-R-L-L-T-L-A-L-P-R-I-R-D-F-R-G-I-N-G-H-Q-F-D-G-Q-G-N-Y-N-F-G-L-T-E-Q-S-M-F-H-E-I-D-P-D-S-I-D-H-V-R-G-M-D-I-T-V-V-T-S-T-K-D-D-K-E-A-Y-A-L-L-K-H-L-G-F-P-F-K-E-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-K-S-G-D-L-V-K-V-I-R-G-K-D-R-G-K-E-G-T-V-K-Q-V-L-S-N-D-R-L-I-V-E-G-V-Q-I-V-K-K-H-V-R-A-T-Q-Q-G-Q-Q-A-G-I-V-S-T-E-A-P-I-H-R-S-N-V-M-V-I-D-P-E-T-K-Q-P-T-R-V-G-I-T-V-K-E-E-A-R-D-G-K-V-K-T-V-R-V-R-V-A-K-K-S-G-K-E-L-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-H-V-A-D-N-T-G-A-K-E-L-L-A-I-R-V-L-G-G-S-K-R-R-Y-A-G-I-G-D-V-I-V-A-S-V-K-D-A-I-P-G-G-S-V-K-K-G-D-V-V-K-A-V-V-V-R-T-V-K-E-S-R-R-A-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-L-G-S-G-R-E-P-K-G-T-R-I-F-G-P-V-G-R-E-L-R-E-H-K-F-M-K-I-V-S-L-A-P-E-V-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-E-E-R-N-F-R-K-V-R-R-G-Y-V-V-S-D-K-M-D-K-T-I-T-V-E-L-E-Q-R-S-T-H-P-L-Y-G-K-V-V-R-S-T-S-K-V-K-A-H-D-E-H-N-D-A-H-I-G-D-L-V-S-I-M-E-T-R-P-L-S-K-T-K-R-W-R-L-E-S-I-I-E-R-A-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-I-P-K-R-T-K-Y-R-K-Q-H-R-P-V-R-S-G-M-S-K-G-G-N-E-I-N-F-G-D-F-A-I-Q-S-L-A-P-A-Y-V-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-I-K-R-G-G-R-V-W-I-T-I-F-P-D-R-P-L-T-K-H-P-L-G-A-R-M-G-S-G-K-G-A-P-E-F-W-I-A-N-V-R-P-G-R-V-M-F-E-I-G-G-V-S-E-D-I-A-K-E-A-L-R-R-A-I-D-K-L-P-M-K-C-R-I-I-A-R-E-G-G-D-I"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-I-A-R-H-V-R-V-T-P-R-K-A-R-R-M-V-D-L-I-R-G-K-K-A-T-E-A-V-T-I-L-K-F-A-P-Q-A-A-A-L-P-V-R-K-T-L-E-S-A-I-A-N-A-R-V-K-A-D-K-A-G-E-P-F-R-E-N-D-L-Y-I-K-E-T-Y-V-D-E-G-V-T-L-K-R-F-R-A-R-A-Q-G-R-A-A-R-I-N-K-R-T-S-H-I-T-V-V-V-A-N-K-E-G-A-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-I-K-K-G-P-F-V-D-A-H-L-Q-K-K-V-D-E-Q-N-E-K-G-T-K-N-V-I-K-T-W-S-R-R-S-M-I-T-P-D-F-I-G-H-T-F-A-V-H-D-G-R-K-H-V-P-V-F-V-T-E-A-M-V-G-H-K-L-G-E-F-A-P-T-K-T-F-K-G-H-V-K-D-D-K-K-A-R-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-V-A-I-H-K-P-A-H-D-V-I-L-K-P-V-V-S-E-K-S-Y-A-A-S-D-R-G-Q-Y-T-F-V-V-A-P-D-A-N-K-V-Q-I-K-Q-A-I-E-E-I-F-K-V-K-V-T-N-V-N-T-L-N-R-A-G-K-K-Q-R-T-R-T-G-F-G-Q-R-A-S-Q-K-R-A-I-V-T-V-A-E-G-Q-T-I-D-I-F-G-N"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-G-Q-K-I-R-I-R-L-K-S-Y-D-H-E-V-I-D-Q-S-A-K-K-I-V-E-T-V-T-N-A-G-A-T-V-V-G-P-V-P-L-P-T-E-K-N-V-F-C-V-I-R-S-P-H-K-Y-K-D-S-R-E-H-F-E-M-R-T-H-K-R-L-I-D-I-V-D-P-T-P-K-A-V-D-S-L-M-H-I-D-L-P-A-D-V-N-I-E-I-K-L"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-T-P-K-P-A-D-L-T-H-D-W-Y-V-I-D-A-T-D-V-V-L-G-R-L-A-T-Q-A-A-I-L-L-R-G-K-N-K-P-T-Y-A-P-H-A-D-S-G-N-H-V-I-I-I-N-A-D-K-I-A-L-T-G-N-K-M-G-K-E-L-Y-S-H-S-G-R-P-G-G-L-R-R-D-S-Y-A-E-L-L-E-K-N-P-E-R-I-I-K-N-A-V-K-G-M-L-P-K-N-R-L-A-K-V-Q-L-D-R-L-R-I-F-R-G-A-E-H-P-H-T-P-Q-K-P-Q-V-F-E-I-A-Q-V-S-Q-Q-A-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-Y-T-N-D-E-L-L-E-A-F-G-E-M-T-L-V-E-L-S-E-F-V-K-A-F-E-E-K-F-D-V-E-A-A-A-P-V-A-A-V-A-A-V-A-G-A-A-A-P-A-E-E-E-K-D-E-F-D-V-I-L-S-A-V-G-D-K-K-I-Q-V-I-K-A-V-R-A-I-T-N-L-G-L-A-E-A-K-A-L-V-D-G-A-P-K-A-V-L-E-K-A-K-K-E-D-A-E-K-A-K-A-Q-L-E-E-A-G-A-S-V-E-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-K-R-P-E-K-E-A-V-V-A-Q-L-T-E-E-F-R-N-A-D-A-V-Y-L-T-E-Y-R-G-L-T-V-P-Q-I-S-D-L-R-E-K-L-G-R-D-T-S-Y-T-V-A-K-N-T-L-A-R-I-A-A-K-E-A-G-I-E-G-L-D-E-I-L-S-G-P-T-A-I-T-F-V-K-G-D-F-I-E-A-A-K-V-I-R-D-F-A-K-D-N-K-A-L-V-I-K-G-A-A-A-D-G-T-V-Y-D-A-E-G-A-K-K-L-A-D-L-K-S-R-P-Q-L-L-A-E-F-A-G-D-I-K-A-S-M-A-K-A-A-Y-L-F-N-A-L-P-T-K-A-V-R-T-I-D-A-L-R-E-K-Q-E-K-A-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-A-E-E-K-Q-E-I-I-A-K-Y-A-T-H-E-G-D-T-G-S-P-E-V-Q-V-A-L-L-S-K-R-I-A-D-L-T-E-H-L-K-E-H-K-H-D-H-H-S-R-R-G-M-Q-L-M-I-G-D-R-R-R-L-L-D-Y-L-K-R-V-D-I-N-R-Y-R-S-L-I-E-R-L-G-L-R-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-L-I-D-Q-A-K-E-Q-M-A-K-T-V-E-N-T-K-E-N-F-S-G-I-R-T-G-R-A-N-P-A-L-L-N-G-I-T-V-D-Y-Y-G-A-P-T-P-I-K-A-V-A-S-I-G-V-P-E-P-R-T-L-S-V-T-P-F-D-A-S-Q-A-G-A-V-E-K-A-L-R-N-S-D-L-G-I-S-P-N-R-D-G-N-V-I-R-L-T-M-P-E-L-T-E-D-R-R-K-E-Y-V-K-L-A-K-G-K-A-E-D-G-K-V-A-V-R-N-I-R-R-K-T-K-E-T-I-D-K-A-V-K-D-G-E-M-G-E-D-E-G-D-R-L-L-K-D-L-D-K-V-T-K-S-V-T-D-E-I-D-T-L-L-E-T-K-Q-K-E-I-M-E-V"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-I-R-E-I-R-V-V-P-D-P-V-L-R-T-P-C-D-E-I-K-E-I-T-P-A-V-R-R-L-V-D-D-L-L-E-T-V-D-D-P-G-R-A-G-L-S-A-N-Q-I-G-V-S-L-R-A-F-S-Y-N-I-D-G-K-V-G-Y-V-L-N-P-V-L-E-E-K-S-G-E-Q-Y-G-D-E-G-C-L-S-V-P-G-L-W-Y-K-T-R-R-A-D-Y-A-R-V-R-G-I-D-L-D-G-N-E-V-V-L-E-G-S-G-L-M-G-R-M-L-Q-H-E-C-D-H-L-D-G-H-V-Y-L-D-R-L-E-K-E-E-R-R-E-A-L-R-Y-M-R-N-R-Q-A-K"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-A-F-D-E-T-Y-N-E-P-E-S-T-E-V-L-V-K-S-L-D-P-E-H-P-A-Q-L-H-Y-A-H-A-G-D-A-G-A-D-L-I-T-T-V-D-V-T-L-K-P-F-E-R-A-L-V-P-T-G-V-A-I-A-L-P-A-G-Y-V-A-L-V-H-P-R-S-G-L-A-A-K-Q-G-V-T-V-L-N-A-P-G-T-V-D-A-G-Y-R-G-E-I-K-V-P-L-I-N-L-D-P-K-H-T-A-V-F-H-P-G-D-R-I-A-Q-L-V-I-Q-R-Y-V-E-A-R-F-I-P-A-E-T-L-P-G-S-D-R-A-E-R-G-F-G-S-T-G-V-A-S"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-A-V-N-A-H-K-K-R-R-V-V-L-E-R-A-S-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-L-L-H-S-F-N-Y-N-F-R-D-R-K-A-R-K-G-D-F-R-K-L-W-I-Q-R-I-N-A-A-V-R-A-E-G-I-T-Y-N-R-F-I-Q-G-L-R-L-A-G-I-E-L-D-R-R-A-L-A-E-I-A-V-S-D-P-N-T-F-K-T-I-V-D-A-A-K-A-A-L-P-E-D-V-N-A-P-V-E-A"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-Q-N-P-D-T-K-V-I-D-T-R-I-S-D-D-G-H-S-I-R-R-R-R-V-C-P-K-C-S-K-R-F-T-T-V-E-T-S-M-L-L-V-T-K-R-S-G-G-V-E-P-F-S-R-D-K-V-I-S-G-V-R-K-A-C-Q-G-R-P-V-R-E-E-D-L-K-L-L-G-Q-K-V-E-E-D-L-R-S-R-G-L-A-E-V-T-S-D-E-V-G-K-A-I-L-K-P-L-R-D-L-D-V-V-A-Y-L-R-F-A-S-V-Y-Q-N-F-A-G-L-E-D-F-Q-S-A-I-D-G-L-R-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-P-K-K-K-V-S-A-L-I-K-L-Q-I-Q-A-G-K-A-N-P-A-P-P-L-G-P-A-L-G-S-H-G-V-N-I-M-D-F-C-K-A-Y-N-A-Q-T-Q-D-K-M-G-Q-V-I-P-V-E-I-T-V-Y-E-D-R-S-F-T-F-V-L-K-T-P-P-A-A-A-L-L-K-K-A-A-G-V-E-K-G-T-E-N-P-L-T-H-K-V-G-S-V-T-K-A-Q-V-R-E-I-A-E-I-K-M-E-D-L-S-A-R-D-I-E-A-G-M-K-I-I-E-G-T-A-R-S-M-G-I-T-V-T-D"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-K-A-G-G-H-Q-E-K-V-E-V-G-D-V-I-L-V-N-R-L-D-A-K-K-G-D-T-V-E-F-P-V-S-L-V-V-D-G-D-K-V-T-L-A-A-A-D-L-A-K-V-S-V-K-A-E-V-V-N-D-E-A-K-G-P-K-I-S-I-Q-K-Y-K-N-K-T-G-V-A-R-R-K-G-H-R-Q-K-L-T-I-V-K-I-T-A-I-A"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-Q-I-D-I-I-A-P-G-R-V-K-E-R-Y-L-R-D-A-I-D-E-Y-S-K-R-L-S-R-Y-C-K-L-N-I-I-E-V-A-D-E-K-T-P-D-H-A-S-E-G-V-D-R-Q-I-K-A-R-E-G-E-R-I-A-K-H-L-K-D-G-A-F-V-I-A-L-A-I-N-G-K-Q-L-S-S-E-E-L-A-A-K-I-N-D-L-G-L-R-G-T-S-H-I-Q-L-V-I-G-G-S-I-G-L-D-D-A-I-L-R-R-A-D-F-L-L-S-F-S-K-M-T-F-P-H-Q-L-M-R-V-I-L-L-E-Q-I-Y-R-A-Y-K-I-N-A-G-E-P-Y-H-K"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-T-M-S-D-D-N-E-N-E-Q-P-L-N-L-D-I-P-D-H-L-E-Y-S-E-E-H-A-W-V-D-R-S-V-D-P-A-I-I-G-I-T-E-Y-A-A-D-Q-L-G-E-L-V-F-V-D-L-P-E-P-G-A-R-V-E-A-G-D-E-I-V-E-L-E-S-S-K-A-V-Q-P-L-I-S-P-V-A-G-T-V-K-Y-V-N-R-D-V-A-D-D-P-S-V-V-N-G-D-P-Y-G-E-G-W-L-L-K-V-E-L-D-D-D-E-P-E-L-L-S-A-D-E-Y-A-K-V-V-R"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-P-K-E-T-G-E-K-L-I-V-Q-N-K-K-A-R-H-D-Y-A-I-E-D-K-Y-E-A-G-L-A-L-T-G-T-E-V-K-S-L-R-E-G-R-A-S-L-S-E-A-F-I-S-I-D-R-R-G-E-M-W-L-E-G-A-N-I-P-E-Y-L-N-G-T-W-N-N-H-A-P-K-R-K-R-K-L-L-L-H-R-L-Q-I-T-K-L-A-R-G-I-E-A-K-G-Y-T-I-V-P-L-S-L-Y-F-K-D-G-R-V-K-A-E-I-A-L-A-R-G-K-K-E-F-D-K-R-Q-A-L-R-E-E-Q-D-K-R-E-A-L-R-A-M-R-Y-A-N-M-R-H"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-G-P-S-K-K-H-V-V-L-P-D-P-I-Y-G-S-T-V-V-A-Q-L-I-N-K-I-L-L-D-G-K-K-S-I-A-E-D-I-V-Y-S-A-L-D-M-V-K-E-K-S-D-Q-E-P-V-A-V-L-K-R-A-L-D-N-I-R-P-S-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-K-P-N-R-A-N-T-L-S-L-R-W-L-T-D-F-S-R-A-R-R-E-K-T-M-A-E-R-L-A-N-E-I-L-D-A-S-N-G-L-G-A-S-V-K-R-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-T-V-F-L-P-I-L-V-C-L-C-G-G-V-G-A-S-C-R-Y-L-L-D-V-T-I-K-T-Y-W-Q-R-A-F-P-L-S-T-F-T-I-N-L-I-A-G-F-L-A-G-L-V-A-A-L-A-L-G-G-T-L-D-E-P-W-R-L-V-L-A-T-G-F-L-G-G-F-S-T-F-S-T-A-I-N-E-M-V-T-L-F-R-K-H-R-Y-P-T-A-A-A-Y-L-V-L-S-L-G-V-P-V-V-A-A-A-C-G-F-L-V"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-D-S-Q-S-P-S-A-G-A-R-P-I-T-H-T-T-T-P-P-A-R-K-L-P-D-I-H-L-D-I-V-L-V-V-F-C-G-G-A-I-G-T-A-I-R-Y-A-F-A-Q-I-P-A-A-G-S-F-H-T-G-T-F-V-A-N-M-L-A-C-F-C-Y-A-G-L-T-A-Y-L-A-G-A-S-R-F-G-A-R-S-K-E-L-A-S-R-G-L-G-M-G-V-C-G-G-L-S-T-M-S-T-L-A-L-E-G-F-T-A-I-R-D-G-Q-V-A-A-G-I-A-Y-L-L-V-T-F-A-L-G-L-V-C-A-S-A-G-V-W-A-G-T-H-L-A-G-S-S-N-V-S-A-E-A-S-A-D-T-N-A-A-T-T-S-K-G-G-K-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-S-E-T-G-P-S-L-Q-R-P-A-T-R-A-A-R-L-S-A-I-E-Q-A-L-A-T-H-I-I-T-S-Q-S-Q-L-S-K-I-L-I-D-E-G-I-A-V-T-Q-A-T-L-S-R-D-L-D-E-M-H-A-V-K-T-R-L-K-D-G-T-V-A-Y-T-V-G-R-S-V-V-A-S-E-G-E-D-V-G-E-R-G-E-A-Q-M-S-R-V-L-N-G-L-V-T-S-V-A-A-A-G-N-L-V-V-V-H-T-P-S-G-A-A-Q-Y-V-A-S-V-I-D-K-Q-P-I-E-G-V-L-G-T-I-A-G-D-D-T-V-M-V-I-C-T-N-D-D-T-A-V-F-R-S-D-W-L-L-S-L-A-S-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-A-S-D-F-W-L-I-A-G-L-G-N-P-G-K-K-Y-E-D-T-R-H-N-M-G-F-M-T-A-D-V-L-A-E-R-W-T-V-N-F-A-D-H-K-G-L-A-M-L-G-K-S-V-M-N-L-D-G-R-T-V-K-F-F-L-A-K-P-L-T-Y-M-N-D-S-G-N-A-V-A-S-I-S-A-Y-Y-Q-I-E-P-D-H-I-V-V-I-H-D-D-M-D-L-E-F-G-R-I-K-V-K-A-G-G-S-A-G-G-H-N-G-I-K-S-I-D-R-S-L-G-T-P-K-Y-A-R-V-R-M-G-V-G-H-S-K-R-G-A-N-A-H-D-N-T-V-N-W-V-L-G-G-F-G-P-D-Q-R-K-Q-L-P-E-F-L-A-D-G-A-D-A-A-E-D-I-I-F-H-G-L-A-K-T-Q-E-K-F-N-G-R"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-V-W-L-G-V-D-L-G-N-A-R-V-G-L-A-L-S-D-P-E-L-T-F-A-H-P-A-G-N-I-H-V-A-G-D-Y-F-F-A-I-D-E-V-L-N-V-I-E-D-E-H-V-D-H-V-I-V-G-L-P-L-Q-M-D-G-T-E-G-K-S-A-K-K-A-R-R-W-A-A-N-L-E-K-R-L-Q-A-E-S-E-D-S-D-S-T-E-Y-Q-I-P-Q-V-S-L-I-D-E-R-L-T-T-V-S-A-H-R-Q-L-F-E-A-H-K-A-S-N-K-H-R-P-V-V-D-Q-Q-S-A-V-V-I-L-Q-T-A-L-D-R-T-R-E-Q"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-V-D-V-T-N-E-T-Q-W-V-I-D-P-K-V-F-S-D-L-G-I-W-V-L-D-Q-M-R-V-S-T-Q-S-D-L-T-I-M-F-V-D-P-D-P-I-A-E-L-H-M-R-W-M-N-L-E-G-P-T-D-V-M-S-F-P-M-D-E-L-R-P-G-D-G-K-T-V-M-E-G-V-L-G-D-I-V-I-C-P-W-V-A-A-Q-Q-A-A-A-A-G-H-S-T-M-Q-E-M-L-L-L-T-I-H-G-I-L-H-L-L-G-Y-D-H-V-T-P-E-Q-E-R-Q-M-F-G-L-Q-R-Q-L-L-L-T-F-F-A-L-R-H-D-A-N-V-Q-A-T-L-P-A-G-T-P-D-A-L-A-L-Y-D-A-A-H-G-A-G-R-D-L-D-S-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-K-K-R-V-L-T-N-E-K-A-H-L-R-N-V-A-V-K-S-G-L-K-T-A-I-R-A-T-R-E-A-I-A-A-G-D-K-A-A-A-E-A-A-Y-K-V-A-A-Q-K-L-D-K-A-A-G-A-G-V-I-H-K-N-Q-A-A-N-R-K-S-G-L-A-V-A-I-N-A-L"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-E-V-T-S-I-Q-N-G-I-I-I-D-H-V-P-A-G-T-S-L-K-V-L-E-Y-L-K-I-D-P-A-K-T-K-L-A-L-I-M-N-A-D-S-K-R-Y-G-S-K-D-I-I-K-I-E-D-D-K-D-I-D-L-D-V-L-G-F-V-A-R-Q-A-T-V-D-V-V-R-G-G-K-I-V-E-K-K-Q-P-N-L-P-E-H-I-V-G-V-I-S-C-V-N-P-R-C-V-T-T-A-E-P-G-I-K-Q-M-F-H-L-V-H-S-E-R-L-E-Y-R-C-D-Y-C-D-E-E-A-K-L"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-A-Q-S-D-I-T-I-D-A-L-S-K-V-G-Q-Q-D-A-E-Y-L-V-S-L-V-R-S-V-P-G-F-P-K-E-G-I-I-F-R-D-F-M-P-V-L-A-D-P-K-G-L-K-I-L-L-K-A-L-E-E-A-L-P-V-S-P-S-E-F-D-S-I-A-G-L-E-S-R-G-F-L-F-G-P-V-M-A-A-H-L-G-K-G-F-I-A-V-R-K-A-G-K-L-P-P-E-T-I-G-E-S-Y-D-L-E-Y-G-T-A-S-V-E-I-E-T-D-A-V-Q-A-G-K-R-V-L-I-V-D-D-L-I-A-T-G-G-T-A-K-A-A-T-D-L-I-E-K-A-G-G-T-V-V-G-F-S-F-V-M-R-L-D-G-L-D-G-L-D-K-L-D-G-K-P-S-S-S-L-I-A-M-P-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-E-R-L-Q-S-H-R-D-F-V-T-V-L-K-R-R-R-K-A-G-G-K-D-I-V-V-H-Y-L-V-P-D-D-H-H-D-D-D-D-R-T-V-H-R-R-L-G-L-A-V-S-K-S-V-G-H-A-V-T-R-N-T-V-K-R-R-F-R-V-L-A-R-A-H-E-D-L-L-P-A-H-C-D-I-V-L-R-A-K-P-S-A-A-T-A-S-F-A-S-L-D-Q-Q-I-A-K-A-F-A-T-V-A-H-K-V-A-E-A"} +{"text": "### FUNCTION Involved in cell division ### SEQUENCE -M-E-Q-V-Q-A-A-L-N-A-T-A-D-K-A-T-L-T-P-Q-M-Q-R-M-M-N-R-Q-A-E-N-T-K-R-V-E-E-T-I-K-G-T-K-S-N-P-R-W-F-V-P-L-F-C-A-L-M-I-I-G-L-I-W-C-V-V-Y-Y-L-S-P-S-G-S-W-P-I-P-N-I-G-A-W-N-L-G-I-G-F-A-L-I-M-I-G-F-L-M-T-M-G-W-R"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-M-W-M-I-C-L-F-G-G-L-G-A-M-A-R-Y-V-L-D-V-S-I-Q-R-G-W-N-R-E-N-R-R-T-N-R-N-F-P-L-S-T-L-V-I-N-G-V-A-S-L-C-A-G-I-A-M-M-S-Y-Y-S-Q-S-V-D-M-D-T-V-M-M-F-V-V-G-F-L-G-G-F-S-T-F-S-T-A-L-N-E-V-V-S-L-I-R-Q-R-R-F-T-L-A-L-G-Y-G-I-A-T-V-A-V-P-L-I-C-V-A-A-G-F-G-I-A-L-L-A-N-P-A"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-A-L-A-Y-D-G-A-I-Q-R-L-I-D-A-F-G-R-L-P-G-I-G-P-K-G-A-Q-R-I-A-F-Y-M-L-S-A-P-E-D-E-A-R-D-L-A-E-A-I-E-E-V-K-A-K-I-R-F-C-D-I-C-G-N-V-C-E-S-S-P-C-P-V-C-A-D-P-R-R-D-R-S-V-I-C-V-V-E-E-P-K-D-V-M-S-I-E-R-T-R-E-Y-H-G-L-Y-H-V-L-G-G-A-I-N-P-M-A-N-V-G-P-A-D-L-R-I-P-G-L-L-K-R-L-E-G-D-E-V-K-E-V-I-M-A-L-D-P-N-I-E-G-E-A-T-T-S-Y-L-T-Q-L-L-R-P-V-G-V-K-V-T-R-L-A-S-G-L-P-V-G-S-D-L-E-Y-A-D-E-I-T-L-G-R-A-L-A-G-R-R-E-A"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-M-S-A-H-K-Y-E-L-M-F-I-A-D-P-E-L-D-E-R-G-L-K-K-L-T-E-Q-Y-L-E-L-V-T-K-E-G-G-S-F-D-E-P-D-Y-W-G-R-R-K-L-A-Y-E-I-A-G-K-T-E-G-N-Y-V-V-V-K-Y-T-A-E-P-A-T-S-D-E-L-D-R-V-L-N-L-N-E-S-V-I-R-T-K-I-L-R-K-G"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-R-K-R-P-Q-P-P-V-K-P-F-K-K-K-P-N-P-L-K-A-A-K-V-T-E-I-D-Y-K-D-V-A-L-L-R-K-F-I-S-D-R-G-K-I-R-S-R-R-I-T-G-V-T-V-Q-E-Q-R-E-L-S-K-A-I-K-N-A-R-E-M-A-L-L-P-Y-A-T-S-G-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-E-T-K-V-I-L-T-K-T-V-S-N-L-G-H-S-G-D-V-V-D-V-K-S-G-Y-A-R-N-Y-L-F-P-Q-G-L-A-F-A-W-T-K-G-A-E-A-Q-I-V-A-M-K-R-A-R-L-A-K-A-V-A-T-R-E-D-A-V-A-A-K-A-A-I-E-G-T-T-V-E-I-A-A-K-V-S-E-S-G-K-L-F-G-G-I-S-N-E-A-I-A-V-A-L-S-D-K-A-A-V-N-P-K-A-I-E-V-E-T-I-K-T-T-G-D-F-P-A-K-V-A-L-H-P-E-I-T-A-S-F-F-V-K-V-V-A-E"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-I-S-I-I-I-Q-I-L-L-I-S-V-S-V-A-M-D-A-F-A-V-S-I-G-K-G-L-T-V-S-R-V-R-V-Q-D-A-V-K-S-T-L-W-F-G-G-F-Q-M-L-F-P-I-L-G-Y-F-A-A-S-T-F-S-K-Y-V-T-Q-F-D-H-W-I-I-F-A-L-L-V-F-I-G-G-N-M-V-H-E-A-F-E-E-D-E-E-N-S-K-E-T-A-Q-F-D-W-K-H-M-L-P-L-A-V-A-C-S-I-D-A-F-A-V-G-V-S-L-A-F-M-F-T-K-A-H-M-A-F-A-I-L-S-I-G-V-V-T-G-L-F-S-A-A-G-L-H-I-G-R-A-F-G-S-R-W-Q-K-P-A-Q-I-A-G-G-V-V-L-I-L-L-G-I-K-V-L-L-E-H-L-G-V-I-A-F"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-M-T-Q-A-A-S-G-I-D-L-F-I-P-E-V-Y-D-I-V-W-S-L-I-I-L-V-I-V-A-V-F-F-Y-K-F-F-M-P-K-F-N-A-I-F-D-E-R-A-A-K-I-Q-G-N-I-A-K-A-E-Q-A-R-K-D-A-D-E-A-K-A-K-Y-E-A-Q-L-S-T-A-R-V-D-A-A-K-I-R-D-D-A-R-A-E-A-S-H-I-I-A-D-A-R-S-R-A-E-S-D-A-A-Q-I-T-A-S-A-Q-R-S-I-E-S-Q-H-Q-Q-A-I-V-S-L-K-G-E-V-G-A-L-A-T-A-L-A-G-K-I-L-G-A-K-L-E-D-N-D-V-Q-S-S-M-I-D-S-M-I-D-D-L-G-A-K-K"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-G-F-M-K-N-A-M-S-Y-L-G-M-S-D-V-V-D-D-E-D-D-Y-I-E-E-D-E-E-Q-K-P-A-S-K-S-A-F-D-S-D-H-T-V-T-P-L-A-S-T-T-A-P-A-A-S-S-T-T-K-P-F-P-G-G-R-V-N-R-I-T-T-I-H-P-K-S-Y-E-D-A-Q-L-V-G-R-A-L-R-D-G-V-P-V-V-L-N-L-T-G-V-A-E-A-V-A-Y-R-I-V-D-F-S-A-G-V-V-F-G-V-R-G-S-L-E-R-V-T-P-R-V-F-L-L-S-P-A-Q-V-N-I-K-V-E-E-P-T-K-P-A-S-A-H-D-L-F-A-D"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-T-E-N-T-H-A-G-R-L-I-V-L-T-G-P-T-A-V-G-K-G-T-V-E-A-K-L-R-A-D-H-P-E-V-W-V-S-V-S-A-T-T-R-A-P-R-P-G-E-V-D-G-V-N-Y-W-F-L-T-E-D-E-F-L-A-R-E-A-A-G-E-F-L-E-T-A-V-V-H-G-M-A-H-Y-G-T-L-L-K-P-V-E-E-H-L-A-A-G-V-P-T-I-L-E-I-D-L-Q-G-A-R-R-V-K-Q-R-A-A-E-L-D-L-E-V-V-Y-V-F-I-A-P-P-S-F-E-E-L-E-R-R-L-I-G-R-G-T-E-T-A-E-Q-Q-A-R-R-L-E-T-A-K-V-E-L-A-A-E-S-E-F-D-V-T-I-V-N-E-T-V-D-Q-A-A-A-D-L-W-S-V-I-A-K-E-Y-G-L"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-A-R-S-T-A-R-K-R-A-L-N-T-L-Y-E-A-D-E-K-S-Q-D-I-L-S-L-L-D-E-R-I-A-H-P-G-A-Q-T-P-L-P-D-Y-A-I-E-I-V-K-G-V-A-E-H-R-R-Q-I-D-M-T-L-D-E-H-S-T-G-W-K-V-R-R-M-G-V-V-D-R-N-I-L-R-I-A-A-W-E-I-L-F-T-D-D-V-P-D-K-V-A-I-D-E-A-L-A-L-A-K-T-L-C-D-D-D-S-P-A-F-I-H-G-L-L-S-A-V-C-T-A-K-N-A-A-P-A-P-E-S-V-A-E-E-A-D-E-E-S-S-D-S-A-A-A-A-S-E-P-T-D-E-G-D-V-S-D-S-P-D-S-S-G-A-S-D-E-P-A-A-P-S-A-E-I-Q-P-T-V-D"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-Q-T-T-N-D-I-K-N-G-S-V-L-N-L-D-G-Q-L-W-T-V-M-K-F-Q-H-V-K-P-G-K-G-P-A-F-V-R-T-T-I-K-N-V-L-S-G-K-I-V-D-K-T-F-N-A-G-M-K-M-E-F-E-T-V-D-N-R-T-L-Q-Y-S-Y-E-D-G-D-N-F-V-F-M-D-M-T-T-Y-D-Q-I-M-V-P-K-T-L-L-G-D-K-A-K-F-L-L-E-G-T-D-C-L-V-S-F-H-D-G-T-P-L-S-V-D-L-P-G-S-V-V-L-T-I-T-H-T-E-P-G-L-Q-G-N-R-S-N-A-G-T-K-P-A-T-V-E-T-G-A-E-I-Q-V-P-L-F-I-N-E-G-D-R-V-K-I-N-T-E-D-G-S-Y-T-G-R-E-N-N"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-G-V-S-V-K-P-A-A-R-R-N-A-R-Q-F-A-L-Q-A-I-Y-S-W-Q-L-S-K-E-N-V-A-D-I-E-E-Q-F-L-T-A-E-K-Y-D-E-E-E-H-H-A-N-E-P-K-L-Q-T-P-E-T-D-V-A-Y-F-R-D-L-F-S-G-V-A-L-N-H-M-K-L-D-G-K-M-R-P-Y-L-S-R-P-L-Q-D-L-D-Q-M-E-L-A-L-L-R-M-S-I-Y-E-M-M-N-R-D-D-V-P-Y-K-V-V-I-N-E-A-I-E-L-A-K-V-F-A-A-E-D-S-H-K-F-V-N-G-V-L-D-K-A-A-P-T-L-R-K-K"} +{"text": "### FUNCTION Overproduction of CaiE stimulates the activity of CaiB and CaiD ### SEQUENCE -M-S-I-Y-A-F-E-G-V-I-P-V-V-H-P-T-A-Y-I-H-P-S-A-V-L-I-G-D-V-I-I-G-A-G-V-Y-I-G-P-L-A-S-L-R-G-D-Y-G-R-L-I-V-E-A-G-A-N-L-Q-D-G-C-V-M-H-G-Y-T-D-M-D-T-I-V-Q-E-N-G-H-I-G-H-G-A-I-L-H-S-C-I-I-G-R-D-S-L-V-G-M-N-S-V-I-M-D-G-A-I-I-G-E-E-S-I-V-A-A-M-S-F-V-K-A-G-F-Q-G-Q-A-R-Q-M-L-M-G-S-P-A-K-H-V-R-D-I-S-D-Q-D-M-Q-W-K-R-M-N-T-R-E-Y-Q-D-L-T-V-R-C-R-Q-G-L-V-E-T-T-P-L-T-A-P-E-A-N-R-P-R-L-R-G-T-T-E-V-K-P-K-G-Q"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-V-E-E-K-E-Q-T-V-G-G-F-V-L-A-G-S-A-Q-E-K-T-K-T-A-Q-V-V-A-T-G-Q-G-V-R-T-L-N-G-D-L-V-A-P-S-V-K-A-G-D-R-V-L-V-E-A-H-A-G-L-D-V-K-D-G-D-E-K-Y-I-I-V-G-E-A-N-I-L-A-I-I-E-K"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-T-K-F-R-P-L-H-D-R-V-V-V-R-R-L-E-G-E-Q-K-T-A-G-G-I-I-I-P-D-T-A-Q-E-K-P-M-E-G-E-V-V-A-V-G-P-G-A-R-N-E-Q-G-Q-I-V-A-L-D-V-K-A-G-D-R-V-L-F-G-K-W-S-G-T-E-V-K-I-D-G-E-E-L-L-I-M-K-E-S-D-I-M-G-V-V-T-A"} +{"text": "### FUNCTION Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization ### SEQUENCE -M-L-L-Q-G-T-H-R-I-G-R-M-A-M-L-L-A-L-A-D-E-N-E-S-P-V-L-S-I-P-K-G-W-K-Y-C-T-G-K-V-G-S-M-N-S-Q-K-V-V-A-A-M-E-T-A-A-K-S-N-Q-V-I-E-T-D-V-Y-R-E-T-H-A-L-Y-H-A-I-M-E-A-L-Y-G-V-T-R-G-Q-I-Q-L-A-D-V-L-R-T-V-G-L-R-F-A-I-V-R-G-T-P-Y-D-G-K-K-E-G-E-W-V-A-V-A-L-Y-G-T-I-G-A-P-V-K"} +{"text": "### FUNCTION Involved in chromosome condensation, segregation and cell cycle progression May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division Not required for mini-F plasmid partitioning Probably acts via its interaction with MukB and MukE Overexpression results in anucleate cells It has a calcium binding activity ### SEQUENCE -M-S-D-F-S-Q-T-V-P-E-L-V-A-W-A-R-K-N-D-F-A-L-T-L-P-T-E-R-L-A-F-L-L-A-I-A-T-L-N-G-E-R-L-D-G-E-M-S-E-G-D-L-V-D-V-F-R-H-V-S-K-T-F-E-Q-T-H-E-T-V-A-Q-R-A-N-N-A-I-N-D-L-V-K-Q-R-L-L-N-R-F-T-S-E-L-A-E-G-N-A-I-Y-R-L-T-P-L-G-I-S-I-S-D-Y-Y-I-R-Q-R-E-F-S-T-L-R-L-S-M-Q-L-S-I-V-A-Q-E-L-R-A-A-G-D-A-A-E-E-G-G-D-E-F-H-W-H-R-N-V-F-A-P-L-K-Y-S-V-A-E-I-F-D-S-I-D-L-T-Q-R-L-M-D-E-A-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-D-S-S-N-A-H-E-A-E-N-P-T-V-P-T-P-D-N-E-I-Q-D-L-Q-Q-E-I-A-T-L-K-A-E-L-K-E-K-N-D-K-Y-L-M-V-L-A-E-S-E-N-A-R-K-R-M-Q-K-E-R-Q-E-M-M-Q-Y-A-V-E-N-A-L-I-D-F-L-V-P-I-E-S-M-E-K-A-L-G-F-A-S-Q-M-S-D-E-V-K-N-W-A-L-G-F-N-M-I-L-Q-Q-F-K-Q-V-F-E-E-K-G-I-V-E-Y-S-S-V-G-Q-K-F-N-P-F-L-H-E-A-V-E-T-E-E-T-T-K-V-P-E-G-T-I-V-E-E-F-S-K-G-Y-K-I-G-D-R-P-I-R-V-A-K-V-K-V-S-K-A-P-A-P-Q-G-T-E-A-E-I-E-N-N-N-E"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-L-A-E-S-V-L-G-N-L-K-E-G-G-S-S-K-E-L-D-F-I-D-L-E-W-F-D-A-Q-K-R-M-G-R-F-T-S-Q-K-G-A-E-L-V-L-K-L-K-N-P-P-K-M-G-L-C-D-G-D-I-L-F-E-D-A-T-S-L-I-A-I-N-I-I-P-T-P-T-L-H-V-Y-A-D-S-T-A-Q-V-A-R-L-C-Y-E-V-G-N-R-H-A-S-L-Y-Y-G-D-S-P-L-S-F-K-T-P-F-E-R-P-L-Q-V-L-F-D-K-L-A-L-R-Y-E-V-L-K-S-K-L-D-A-S-Q-R-I-S-V-S-A-P-H-A-D-P-L-Q-E-G-S-A-P-L-K-F-K-S-A-L-D-L-Q-I-V-I-K-K"} +{"text": "### FUNCTION Specifically methylates the N7 position of guanine in position 527 of 16S rRNA ### SEQUENCE -M-R-A-K-L-D-L-F-T-H-L-L-L-E-W-G-S-V-H-N-L-S-G-A-K-N-H-Q-D-I-E-H-N-I-Q-D-S-L-Q-V-L-D-F-I-A-P-F-K-S-C-L-D-I-G-S-G-A-G-F-P-A-I-P-L-S-L-A-C-S-N-A-R-F-I-L-L-E-P-N-A-K-K-V-A-F-L-H-H-V-K-L-A-L-N-L-N-N-L-E-I-Q-R-M-R-I-E-H-V-S-P-Q-S-V-L-V-D-L-I-T-S-R-A-L-M-N-A-Q-N-L-I-A-L-S-A-P-F-L-R-E-Q-G-H-F-L-F-Y-K-G-S-H-L-R-T-E-I-A-C-A-D-H-E-C-H-V-Y-G-K-R-V-Y-F-Y-S-Q-R-R-D-F-A"} +{"text": "### FUNCTION May function as a transcriptional regulator that controls feoABC expression ### SEQUENCE -M-A-G-L-L-Q-V-R-D-A-L-A-L-R-A-T-S-G-A-Q-L-S-Q-S-L-A-T-P-L-P-L-V-Q-A-M-L-D-R-L-T-A-M-G-K-V-E-R-I-E-Q-D-D-G-A-C-L-S-G-G-C-K-S-C-P-Q-P-R-G-A-A-R-C-S-T-G"} +{"text": "### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-N-P-Q-P-S-G-M-T-W-N-L-L-L-L-T-W-L-V-A-L-I-S-T-L-S-A-L-F-I-G-E-V-M-G-Q-A-P-C-V-L-C-W-F-Q-R-A-F-M-F-P-L-T-V-I-L-A-I-A-C-Y-R-S-D-F-T-V-W-R-Y-A-L-P-L-T-V-I-G-A-A-L-A-F-V-H-T-L-L-Y-A-G-L-I-P-Q-P-I-Q-P-C-T-A-T-G-P-S-C-S-G-A-G-M-T-L-F-G-V-V-P-L-P-A-L-A-L-F-A-F-I-I-I-A-I-L-L-I-I-I-R-R-R-T-T-P"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-K-P-I-G-E-R-V-L-L-K-P-I-K-K-E-E-K-T-K-S-G-I-L-L-S-S-K-S-S-N-T-D-T-K-N-E-A-E-V-V-A-L-G-K-G-E-K-L-E-G-I-K-V-G-D-K-V-I-F-N-K-F-S-G-N-E-I-E-D-G-D-I-K-Y-L-I-V-N-A-D-D-I-L-A-V-I-E"} +{"text": "### FUNCTION May act as a membrane anchor for the tetrachloroethene reductive dehalogenase PceA ### SEQUENCE -M-N-I-Y-D-V-L-I-W-M-A-L-G-M-T-A-L-L-I-Q-Y-G-I-W-R-Y-L-K-G-K-G-K-D-T-I-P-L-Q-I-C-G-F-L-A-N-F-F-F-I-F-A-L-A-W-G-Y-S-S-F-S-E-R-E-Y-Q-A-I-G-M-G-F-I-F-F-G-G-T-A-L-I-P-A-I-I-T-Y-R-L-A-N-H-P-A-K-K-I-R-E-S-S-D-T-I-S-A"} +{"text": "### FUNCTION May act as a membrane anchor for the tetrachloroethene reductive dehalogenase PceA ### SEQUENCE -M-N-I-Y-D-V-L-I-W-M-A-L-G-M-T-A-L-L-I-Q-Y-G-I-W-R-Y-L-K-G-K-G-K-D-T-I-P-L-Q-I-C-G-F-L-A-N-F-F-F-I-F-A-L-A-W-G-Y-S-S-F-S-E-R-E-Y-Q-A-I-G-M-G-F-I-F-F-G-G-T-A-L-I-P-A-I-I-T-Y-R-L-A-N-H-P-A-K-K-I-R-E-S-S-D-S-I-S-A"} +{"text": "### FUNCTION Catalyzes the reduction of arsenate ### SEQUENCE -M-S-K-K-T-L-Y-F-L-C-T-G-N-S-C-R-S-Q-M-A-E-G-W-A-K-K-Y-L-N-N-N-E-W-D-V-R-S-A-G-L-E-A-H-G-L-N-P-N-A-V-K-A-M-K-E-A-G-V-D-I-S-N-Q-T-S-D-V-I-D-P-E-I-L-N-N-A-D-L-V-V-T-L-C-G-H-A-A-D-H-C-P-V-T-P-P-H-V-K-R-E-H-W-G-F-D-D-P-A-K-A-E-G-T-D-E-E-K-W-A-F-F-Q-R-V-R-D-E-I-A-E-R-I-Q-R-F-A-E-T-G-K"} +{"text": "### FUNCTION Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine ### SEQUENCE -I-A-G-C-Q-N-V-V-L-C-S-P-P-P-I-A-D-E-I-L-Y-A-A-Q-L-C-G-V-Q-E-I-F-N-V-G-G-A-Q-A-I-A-A-L-A-F-G-S-E-S-V-P-K-V-D-K-I-F-G-P-G-N-A-F-V-T-E-A-K-R-Q-V-S-Q-R-L-D-G-A-A-I-D-M-P-A-G-P-S-E-V-L-V-I-A-D-S-G-A-T-P-D-F-V-A-S-D-L-L-S-Q-A-E-H-G-P-D-S-Q-V-I-L-L-T-P-D-A-D-I-A-R-K-V-A-E-A-V-E-R-Q-L-A-E-L-P-R-A-D-T-A-R-Q-A-L-S-A-S-R-L-I-V-T-K-D-L-A-Q-C-V"} +{"text": "### FUNCTION Represses transcription of the icaADBC operon necessary for biofilm production ### SEQUENCE -M-K-D-K-I-I-D-N-A-I-T-L-F-S-E-K-G-Y-D-G-T-T-L-D-D-I-S-K-S-V-N-I-K-K-A-S-L-Y-Y-H-Y-D-N-K-E-E-I-Y-R-K-S-V-E-N-C-F-N-Y-F-I-D-F-L-L-R-N-H-D-D-N-Y-S-I-D-G-L-Y-Q-F-L-F-K-F-I-F-D-V-D-E-R-Y-I-K-L-Y-V-Q-L-S-S-A-P-E-A-L-N-S-E-I-K-H-H-L-Q-E-I-N-T-T-L-H-D-E-L-I-K-Y-Y-D-P-T-H-I-A-L-N-K-E-D-F-I-N-L-I-L-L-F-L-E-T-W-Y-F-R-A-S-F-S-Q-K-F-G-V-I-E-D-S-K-N-R-F-K-D-Q-V-Y-S-L-L-N-V-F-L-K-K"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-D-Y-F-T-L-F-G-L-P-A-R-Y-A-L-D-R-E-L-L-A-T-R-Y-Q-E-L-Q-R-Q-F-H-P-D-R-F-A-N-Q-P-E-R-E-K-T-L-A-L-Q-Q-A-T-T-I-N-T-G-Y-Q-T-L-K-H-P-L-K-R-A-E-Y-M-L-S-Q-Q-G-F-D-L-S-N-E-Q-H-T-M-Q-D-T-A-F-L-M-Q-Q-L-E-L-R-E-E-L-D-A-I-E-H-S-S-D-T-E-A-V-L-S-G-F-S-S-R-L-N-K-M-I-K-T-R-R-E-Q-M-E-Q-Q-L-D-A-A-E-W-L-I-A-A-D-T-V-R-K-L-R-F-L-D-K-L-Q-Q-Q-V-E-Q-L-E-E-R-L-L-G-D-F"} +{"text": "### FUNCTION Is able to transfer iron-sulfur clusters to apo-ferredoxin Multiple cycles of cluster formation and transfer are observed, suggesting that IscA acts catalytically Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB ### SEQUENCE -M-S-I-S-L-T-E-S-A-A-Q-R-I-V-A-F-L-D-N-R-G-K-G-V-G-L-R-L-G-V-R-T-S-G-C-S-G-M-A-Y-V-L-E-F-A-D-V-V-N-E-E-D-Q-V-F-E-D-K-G-V-K-V-I-V-D-G-K-S-I-L-Y-L-D-G-T-E-L-D-F-V-K-E-G-L-N-E-G-F-K-F-N-N-P-N-V-S-S-E-C-G-C-G-E-S-F-H-V"} +{"text": "### FUNCTION Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins ### SEQUENCE -M-R-L-T-S-K-G-R-Y-A-V-T-A-M-L-D-V-A-L-H-S-Q-E-G-P-V-P-L-A-D-I-S-E-R-Q-G-I-S-L-S-Y-L-E-Q-L-F-S-R-L-R-K-N-G-L-V-S-S-V-R-G-P-G-G-G-Y-L-L-G-R-D-A-G-R-I-F-V-A-E-V-I-S-A-V-D-E-S-V-D-A-T-R-C-Q-G-K-E-G-C-Q-G-G-D-R-C-L-T-H-A-L-W-R-D-L-S-E-R-I-T-S-F-L-G-S-I-S-L-E-E-L-V-K-N-Q-E-V-L-D-V-A-D-R-Q-D-S-D-K-R-R-T-P-N-G-R-P-Q-E-T-I-N-V-N-L-R-A"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-T-Y-E-G-E-L-I-A-E-G-L-R-F-G-I-V-A-S-R-F-N-H-A-L-V-D-R-L-V-E-G-A-I-D-C-I-L-R-H-G-G-R-E-E-D-I-T-L-V-R-V-P-G-S-W-E-I-P-V-A-V-G-E-L-A-R-R-E-E-I-D-A-V-I-A-I-G-V-L-I-R-G-A-T-P-H-F-D-Y-I-A-S-E-V-S-E-G-L-A-N-L-S-L-E-L-R-K-P-I-T-F-G-V-I-T-A-D-T-L-E-Q-A-I-E-R-A-G-T-K-H-G-N-K-G-W-E-A-A-L-S-A-I-E-M-A-N-L-F-K-K-L-R"} +{"text": "### FUNCTION Structural component of flagellum, the bacterial motility apparatus Part of the rod structure of flagellar basal body ### SEQUENCE -M-A-I-S-F-D-K-A-F-G-I-H-Q-Y-A-L-S-V-R-S-K-R-A-E-V-L-S-S-N-I-A-N-A-D-T-P-G-F-K-A-R-D-I-N-F-S-Q-A-L-E-E-A-Q-H-Q-Q-G-F-G-L-A-T-T-S-E-K-H-F-A-L-Q-S-D-A-P-G-L-T-Q-Y-R-N-P-L-Q-P-D-T-G-D-G-N-T-V-D-V-Q-Q-E-R-S-E-F-L-R-N-S-L-E-Y-Q-T-S-L-E-F-M-N-S-K-I-S-G-L-L-K-A-L-K-G-E-Q"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-K-E-I-L-Q-N-S-A-H-A-S-V-R-M-Q-R-I-S-P-R-K-A-R-L-V-A-D-L-I-R-Y-K-S-A-T-Q-A-I-V-I-L-K-H-T-H-K-K-A-S-E-I-I-L-K-L-L-N-S-A-I-A-N-A-T-N-N-A-G-L-D-A-T-K-L-Y-V-T-T-I-L-V-N-D-G-P-T-L-K-R-F-Q-P-H-S-R-G-R-A-Y-A-I-L-K-R-T-S-H-F-F-I-E-L-T-E-I-N-N-V-E-E-I-N-K-K-G-D-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-A-P-F-V-D-D-H-L-M-K-K-V-L-A-I-I-E-N-K-S-P-K-R-P-I-K-T-W-S-R-R-S-T-I-Y-P-E-F-I-G-L-T-F-Q-V-H-N-G-H-A-F-I-D-V-F-V-T-N-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-N-G-H-G-A-D-K-G-K-K"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-G-K-G-F-G-F-S-L-G-K-M-K-E-L-A-D-A-F-K-K-A-Q-Q-V-Q-E-G-A-K-Q-V-Q-E-D-L-N-N-M-E-I-E-G-Q-A-Q-G-G-L-V-K-V-W-V-S-G-N-Q-E-P-L-R-A-E-I-A-P-E-A-L-N-E-G-A-E-V-L-S-E-L-V-A-A-A-M-K-D-A-Y-Q-K-S-T-A-A-M-K-E-K-M-E-A-L-T-A-G-L-G-I-P-G-L"} +{"text": "### FUNCTION Contributes to virulence and biofilm formation ### SEQUENCE -M-Y-L-Y-T-S-Y-G-T-Y-Q-F-L-N-Q-I-K-L-N-H-Q-E-R-S-L-F-Q-F-S-T-N-D-S-S-I-I-L-E-E-S-E-G-K-S-I-L-K-H-P-S-S-Y-Q-V-I-D-S-T-G-E-F-N-E-H-H-F-Y-S-A-I-F-V-P-T-S-E-D-H-R-Q-Q-L-E-K-K-L-L-H-V-D-V-P-L-S-N-F-G-G-F-K-S-Y-R-L-L-K-P-T-E-G-S-T-Y-K-I-Y-F-G-F-A-N-R-T-A-Y-E-D-F-K-A-S-D-I-F-N-E-N-F-S-K-D-A-L-S-Q-Y-F-G-A-S-G-Q-H-S-S-Y-F-E-R-Y-L-Y-P-I-E-D-H"} +{"text": "### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate forming two phosphate ions ### SEQUENCE -M-G-Y-K-D-L-P-P-G-K-N-P-P-E-D-I-Y-V-V-I-E-I-P-Q-G-S-G-I-K-Y-E-L-D-K-D-T-G-V-I-F-V-D-R-F-L-F-T-A-M-Y-Y-P-F-N-Y-G-F-I-P-Q-T-L-A-D-D-G-D-P-V-D-V-L-V-I-S-R-E-P-V-A-P-G-S-V-M-R-C-R-P-I-G-M-L-E-M-R-D-E-E-G-I-D-T-K-L-I-A-V-P-H-E-K-L-D-P-T-Y-S-D-I-K-T-V-D-Q-L-P-E-I-I-R-E-R-I-K-H-F-F-E-H-Y-K-E-L-E-P-G-K-W-V-K-V-E-N-W-R-G-L-Q-D-A-I-E-E-I-K-K-G-I-E-N-Y-K-K-G-G-K"} +{"text": "### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-E-E-Q-V-L-S-L-L-E-E-L-C-E-D-E-V-V-R-E-D-L-D-I-N-L-R-D-E-G-L-L-D-S-L-G-F-V-E-M-L-V-R-M-E-E-V-F-G-F-A-T-A-P-T-E-V-T-Y-E-E-I-D-T-P-R-R-V-M-A-Y-V-K-K-R-V-A-A-L"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-E-I-K-K-D-A-Q-E-R-M-D-K-S-V-E-A-L-K-N-N-L-S-K-V-R-T-G-R-A-H-P-S-L-L-S-G-I-S-V-E-Y-Y-G-A-A-T-P-L-N-Q-V-A-N-V-V-A-E-D-A-R-T-L-A-I-T-V-F-D-K-E-L-T-Q-K-V-E-K-A-I-M-M-S-D-L-G-L-N-P-M-S-A-G-T-I-I-R-V-P-L-P-P-L-T-E-E-R-R-K-D-L-V-K-I-V-R-G-E-A-E-G-G-R-V-A-V-R-N-I-R-R-D-A-N-N-D-L-K-A-L-L-K-D-K-E-I-S-E-D-E-D-R-K-A-Q-E-E-I-Q-K-L-T-D-V-A-V-K-K-I-D-E-V-L-A-A-K-E-K-E-L-M-E-V"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-Q-Y-V-D-D-H-L-M-C-D-I-D-G-N-R-L-T-A-A-A-I-L-G-Q-D-G-S-V-W-S-Q-S-A-T-F-P-A-F-K-P-E-E-I-A-A-I-L-K-D-F-D-Q-P-G-T-L-A-P-T-G-L-F-L-G-G-T-K-Y-M-V-I-Q-G-E-A-G-A-V-I-R-G-K-K-G-S-G-G-I-T-V-K-K-T-N-Q-A-L-I-I-G-I-Y-D-E-P-L-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-I-E-Q-G-L"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-A-Y-V-D-D-H-L-M-C-E-I-E-G-N-H-L-S-A-A-A-I-I-G-H-D-G-S-V-W-A-Q-S-A-T-F-P-Q-L-K-P-E-E-V-T-G-I-L-N-D-F-N-E-P-G-S-L-A-P-T-G-L-Y-L-G-G-T-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-P-G-G-V-T-V-K-K-S-T-L-A-L-L-I-G-I-Y-D-E-P-M-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-V-E-Q-G-L"} +{"text": "### FUNCTION Probable transcription factor ### SEQUENCE -M-A-S-S-S-M-S-S-S-S-S-W-T-S-K-Q-N-K-M-F-E-R-A-L-A-V-Y-D-K-D-T-P-D-R-W-Q-N-V-A-K-A-V-G-S-K-S-A-E-E-V-K-R-H-Y-D-I-L-V-E-D-L-M-N-I-E-Q-D-L-V-P-L-P-K-Y-K-T-V-D-V-G-S-K-S-R-G-I-D-D-F-D-L-R-L-M-K-N-M-R-I-Q"} +{"text": "### FUNCTION Gibberellin-regulated protein that may function in hormonal controlled steps of development such as seed germination, flowering and seed maturation ### SEQUENCE -M-K-K-M-N-V-V-A-F-V-T-L-I-I-S-F-L-L-L-S-Q-V-L-A-E-L-S-S-S-S-N-N-E-T-S-S-V-S-Q-T-N-D-E-N-Q-T-A-A-F-K-R-T-Y-H-H-R-P-R-I-N-C-G-H-A-C-A-R-R-C-S-K-T-S-R-K-K-V-C-H-R-A-C-G-S-C-C-A-K-C-Q-C-V-P-P-G-T-S-G-N-T-A-S-C-P-C-Y-A-S-I-R-T-H-G-N-K-L-K-C-P"} +{"text": "### FUNCTION Involved in the transport of copper ### SEQUENCE -M-D-H-G-N-M-P-P-S-S-P-S-S-M-V-N-H-T-N-S-N-M-I-M-M-H-M-T-F-F-W-G-K-N-T-E-I-L-F-S-G-W-P-G-T-S-L-G-M-Y-V-L-C-L-I-V-V-F-L-L-A-V-I-V-E-W-L-A-H-S-S-I-L-R-G-R-G-S-T-S-R-A-K-G-L-V-Q-T-A-V-Y-T-L-K-T-G-L-A-Y-L-V-M-L-A-V-M-S-F-N-G-G-V-F-I-V-A-I-A-G-F-A-V-G-F-M-L-F-G-S-T-A-F-K-N-P-S-D-D-E-K-P-F-E-Q-L"} +{"text": "### FUNCTION Heavy-metal-binding protein ### SEQUENCE -M-T-T-K-K-I-E-I-K-V-D-I-D-C-E-K-C-K-H-A-I-M-E-A-V-T-E-L-E-G-V-N-I-V-S-L-D-Q-E-K-S-I-L-T-V-V-G-T-M-D-P-V-C-V-A-E-Q-L-K-K-I-N-K-K-P-V-V-I-S-V-G-P-P-K-K-P-D-P-K-P-D-P-K-K-D-P-C-F-I-P-Y-C-Y-Y-T-P-R-D-M-V-S-V-N-T-Y-E-S-G-S-G-C-T-I-V"} +{"text": "### FUNCTION LEA proteins are late embryonic proteins abundant in higher plant seed embryos The function of those proteins is not known ### SEQUENCE -M-S-E-E-Q-L-Q-K-P-I-D-C-A-D-V-K-G-E-A-E-K-I-S-T-T-E-G-G-I-K-A-A-E-D-K-E-K-G-V-V-A-E-A-S-G-E-Q-A-E-G-E-V-N-Q-K-K-V-V-A-N-P-L-K-S-E-G-T-I-T-I-G-E-A-L-E-A-A-V-L-T-A-G-N-K-P-V-E-W-S-D-A-A-A-I-Q-A-A-E-V-R-A-T-G-R-T-N-I-M-P-G-G-V-A-A-S-A-Q-S-A-A-T-L-N-A-R-I-G-S-D-D-T-K-T-T-L-A-D-V-L-T-G-A-S-S-K-L-P-S-D-K-A-A-T-R-K-D-A-E-G-V-T-G-A-E-M-R-N-D-P-H-L-T-T-Y-P-T-G-V-A-A-S-V-A-A-A-A-R-I-N-Q-S-K"} +{"text": "### FUNCTION Thionins are small plant proteins which are toxic to animal cells They seem to exert their toxic effect at the level of the cell membrane Their precise function is not known ### SEQUENCE -M-A-T-N-K-S-I-K-S-V-V-I-C-V-L-I-L-G-L-V-L-E-Q-V-Q-V-E-G-K-S-C-C-K-N-T-T-G-R-N-C-Y-N-A-C-H-F-A-G-G-S-R-P-V-C-A-T-A-C-G-C-K-I-I-S-G-P-T-C-P-R-D-Y-P-K-L-N-L-L-P-E-S-G-E-P-N-A-T-E-Y-C-T-I-G-C-R-T-S-V-C-D-N-M-D-N-V-S-R-G-Q-E-M-K-F-D-M-G-L-C-S-N-A-C-A-R-F-C-N-D-G-D-V-I-Q-S-V-E-A"} +{"text": "### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-D-H-D-K-T-G-C-Q-S-P-P-E-G-P-K-L-C-T-N-N-C-G-F-F-G-S-A-A-T-M-N-M-C-S-K-C-H-K-D-M-L-F-Q-Q-E-Q-G-A-K-F-A-S-A-V-S-G-T-S-S-S-S-N-I-I-K-E-T-F-T-A-A-L-V-D-I-E-T-K-S-V-E-P-M-T-V-S-V-Q-P-S-S-V-Q-V-V-A-E-V-V-A-P-E-E-A-A-K-P-K-G-P-S-R-C-T-T-C-N-K-R-V-G-L-T-G-F-K-C-R-C-G-S-L-F-C-G-T-H-R-Y-A-D-V-H-D-C-S-F-N-Y-H-A-A-A-Q-E-A-I-A-K-A-N-P-V-V-K-A-E-K-L-D-K-I"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-D-H-L-M-C-D-I-E-G-T-G-Q-H-L-T-A-A-A-I-L-G-L-D-G-T-V-W-A-K-S-D-K-F-P-E-F-K-P-E-E-M-K-G-I-I-N-E-F-N-E-V-G-T-L-A-P-T-G-L-F-L-G-G-A-K-Y-M-V-L-Q-G-E-A-G-A-V-I-R-G-K-K-G-A-G-G-I-C-I-K-K-T-G-Q-A-M-V-M-G-I-Y-D-E-P-V-A-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-V-D-Q-N-M"} +{"text": "### FUNCTION Actin-depolymerizing protein Severs actin filaments ### SEQUENCE -M-A-N-S-A-S-G-L-A-V-N-D-E-C-K-F-K-F-Q-E-L-K-T-R-R-G-F-R-F-I-V-F-K-I-D-D-K-A-M-E-I-K-V-E-R-L-G-Q-T-A-E-G-Y-E-D-F-A-A-T-L-P-A-D-E-C-R-Y-A-V-Y-D-L-D-F-V-T-D-E-N-C-Q-K-S-K-I-F-F-F-S-W-S-P-D-T-A-R-T-R-S-K-M-L-Y-A-S-S-K-D-R-F-R-R-E-L-D-G-I-Q-C-E-I-Q-A-T-D-P-S-E-M-S-L-D-I-I-R-A-R-A-H"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-V-Y-Q-D-L-L-S-G-D-E-L-L-S-D-S-F-T-Y-K-E-L-E-N-G-V-L-W-E-V-E-G-K-W-V-T-Q-G-P-V-D-V-D-I-G-A-N-P-S-A-E-G-G-E-D-E-S-V-D-D-T-A-V-K-V-V-D-I-V-D-T-F-R-L-Q-E-Q-P-P-F-D-K-K-S-F-V-S-Y-I-K-K-Y-I-K-N-L-T-A-V-L-E-P-E-K-A-D-E-F-K-K-G-V-E-G-A-T-K-F-L-L-S-K-L-K-D-L-Q-F-F-V-G-E-S-M-K-D-D-A-S-V-A-F-A-Y-Y-K-D-G-A-T-N-S-T-F-L-Y-F-S-H-G-L-K-E-I-K-C"} +{"text": "### FUNCTION Ubiquitin-like modifier involved in autophagosomes formation With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton Required for selective autophagic degradation of the nucleus as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production Participates also in membrane fusion events that take place in the early secretory pathway Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy ### SEQUENCE -M-S-S-F-K-K-E-H-P-F-E-K-R-Q-A-E-A-Q-R-I-R-S-K-Y-P-D-R-I-P-V-I-C-E-K-A-D-R-S-D-I-P-D-I-D-K-K-K-Y-L-V-P-A-D-L-T-V-G-Q-F-V-Y-V-I-R-K-R-I-K-L-S-P-E-K-A-I-F-I-F-I-N-N-V-L-P-P-T-A-A-L-M-S-N-I-Y-E-E-Q-K-D-V-D-G-F-L-Y-I-T-Y-S-G-E-N-T-F-G-Q"} +{"text": "### FUNCTION The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways ### SEQUENCE -M-A-A-Q-P-V-I-K-V-A-G-L-C-G-S-L-R-K-G-S-Y-N-R-G-L-L-N-A-A-M-E-I-C-K-D-S-I-T-G-M-E-I-E-Y-V-D-I-S-P-L-P-F-L-N-T-D-L-E-V-N-G-T-Y-P-P-V-V-E-A-F-R-K-K-I-E-E-A-D-C-F-L-F-A-S-P-E-Y-N-Y-S-I-T-G-P-L-K-N-A-I-D-W-A-S-R-P-P-N-V-W-A-D-K-A-A-A-M-V-S-A-G-G-G-F-G-G-G-R-S-Q-Y-H-L-R-Q-I-G-V-F-L-D-L-H-F-I-N-K-P-E-F-F-L-N-A-F-Q-Q-P-P-K-F-D-S-D-G-V-L-T-D-E-E-T-K-Q-R-L-R-A-V-L-L-A-L-Q-A-L-A-L-K-L-K-G-K-C-E"} +{"text": "### FUNCTION May cover virion head capsid and play a role in capsid stabilization ### SEQUENCE -M-A-N-P-N-F-T-P-S-W-P-L-Y-K-D-A-D-G-V-Y-V-S-A-L-P-I-K-A-I-K-Y-A-N-D-G-S-A-N-A-E-F-D-G-P-Y-A-D-Q-Y-M-S-A-Q-T-V-A-V-F-K-P-E-V-G-G-Y-L-F-R-S-Q-Y-G-E-L-L-Y-M-S-K-T-A-F-E-A-N-Y-T-S-A-S-G-S-V-A-N-A-E-T-A-D-K-L-S-T-A-R-T-I-T-L-T-G-A-V-T-G-S-A-S-F-D-G-S-A-N-V-T-I-E-T-T-S-G-S"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-M-F-L-F-V-S-L-F-M-F-I-F-K-W-Q-R-L-I-F-I-L-I-S-L-E-F-L-M-L-S-L-F-L-K-F-S-Y-L-L-S-E-M-M-F-F-Y-F-M-C-F-S-V-I-S-S-I-L-G-M-V-V-M-V-G-N-M-K-F-F-G-S-D-N-C-I-F"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-N-L-T-L-I-L-F-L-I-G-I-L-G-F-V-L-N-R-K-N-I-I-L-M-L-I-S-I-E-I-M-L-L-A-I-T-F-L-I-L-V-S-S-L-N-I-D-D-I-L-G-Q-T-Y-A-I-Y-I-I-V-V-A-G-A-E-S-A-I-G-L-G-I-L-V-A-F-Y-R-L-R-G-S-V-A-I-E-Y-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-S-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-S-Y-F-F-N"} +{"text": "### FUNCTION This b-type cytochrome is tightly associated with the reaction center of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-T-I-D-R-I-Y-P-I-F-T-V-R-W-L-A-I-H-G-L-A-V-P-T-V-F-F-L-G-S-I-S-A-M-Q-F-I-Q-R"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-T-I-S-I-S-C-L-L-V-S-F-T-G-Y-A-I-Y-T-S-F-G-R-P-S-E-Q-L-R-D-P-F-E-D-H-E-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-I-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-G-G-K"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-N-K-K-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-E-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-N-T-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-M-K"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-I-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-N-L-V-A-I-F-V-S-C-L-L-V-S-L-T-G-Y-A-L-Y-T-S-F-G-R-P-S-E-G-L-I-D-P-F-D-N-H-E-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-L-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-G-G-K-E-N"} +{"text": "### FUNCTION Binds 5S rRNA, forms part of the central protuberance of the 50S subunit ### SEQUENCE -M-T-Q-R-L-K-N-L-Y-T-K-T-I-V-P-K-L-T-T-N-F-N-Y-S-N-M-H-E-V-P-K-I-E-K-I-V-I-N-R-G-I-G-D-A-S-Q-N-Q-K-I-V-E-S-S-L-K-E-L-A-M-I-A-G-Q-K-G-V-V-T-R-S-K-K-A-I-A-G-F-K-L-R-Q-Q-M-P-V-G-V-T-V-T-L-R-G-D-R-M-Y-G-F-L-D-R-L-I-H-L-A-L-P-R-V-R-D-F-Q-G-I-S-S-K-S-F-D-K-K-G-N-Y-S-L-G-L-E-E-Q-L-M-F-P-E-I-E-Y-D-K-I-D-Q-V-R-G-M-D-I-S-I-V-T-T-A-K-T-Q-E-E-G-L-A-L-L-K-E-F-G-L-P-F-K"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-L-D-L-V-K-Y-P-V-I-T-Q-K-T-Y-I-A-L-F-K-D-R-Q-Y-T-F-D-V-D-L-R-L-T-K-P-Q-I-K-K-V-F-E-T-L-F-N-V-D-V-I-S-V-N-T-H-I-P-P-R-Q-K-I-R-V-G-L-A-Q-G-Y-R-P-R-Y-K-R-A-I-I-T-L-K-E-G-Q-S-I-N-Y-S-L-K-N-D-N"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-A-T-L-G-I-I-F-F-A-I-F-F-R-D-P-P-K-V-P-N-K"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-K-S-K-N-H-T-T-H-N-Q-S-R-K-W-H-R-N-G-I-K-K-P-R-S-Q-R-Y-E-S-L-K-G-V-D-P-K-F-L-R-N-M-R-F-A-K-K-H-N-K-K-G-L-R-K-M-Q-T-N-N-A-K-A-M-S-A-R-A-E-A-V-K-A-L-V-K-P-K-E-V-K-P-K-I-P-K-G-V-S-R-K-L-D-R-L-A-Y-I-A-H-P-K-L-G-K-R-A-R-A-R-I-A-K-G-L-R-L-C-R-P-K-A-K-A-K-A-K-D-Q-T-K-A-Q-A-A-A-P-A-S-I-P-A-Q-A-P-K-G-A-Q-A-T-T-K-A-T-E"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-P-R-K-I-E-E-I-K-D-F-L-L-T-A-R-R-K-D-A-K-S-V-K-I-K-K-N-K-D-N-V-K-F-K-V-R-C-S-R-Y-L-Y-T-L-V-I-T-D-K-E-K-A-E-K-L-K-Q-S-L-P-P-G-L-A-V-K-E-P-K"} +{"text": "### FUNCTION Thyroid hormone-binding protein Probably transports thyroxine from the bloodstream to the brain ### SEQUENCE -M-A-S-H-R-L-L-L-L-C-L-A-G-L-V-F-V-S-E-A-G-P-T-G-V-D-E-S-K-C-P-L-M-V-K-V-L-D-A-V-R-G-S-P-A-V-N-V-A-V-N-V-F-K-K-A-A-D-E-T-W-A-P-F-A-S-G-K-T-S-E-S-G-E-L-H-G-L-T-T-E-E-E-F-V-E-G-I-Y-K-V-E-I-D-T-K-S-Y-W-K-S-L-G-I-S-P-F-H-E-H-A-E-V-V-F-T-A-N-D-S-G-P-R-H-Y-T-I-A-A-L-L-S-P-Y-S-Y-S-T-T-A-V-V-T-N-P-K-E"} +{"text": "### FUNCTION The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity ### SEQUENCE -M-Q-S-L-M-Q-A-P-V-L-I-A-L-G-L-L-F-A-A-P-A-Q-A-H-L-K-K-L-G-S-F-S-W-D-N-C-D-E-G-K-D-P-A-V-I-R-S-L-T-L-E-P-D-P-I-L-I-P-G-N-V-T-V-S-V-V-G-S-T-S-V-L-L-S-S-P-L-K-V-E-L-V-L-E-K-E-V-A-G-L-W-I-K-I-P-C-T-D-Y-I-G-S-C-T-F-E-D-F-C-D-V-L-D-M-L-I-P-T-G-E-P-C-P-E-P-L-R-T-Y-G-L-P-C-H-C-P-F-K-E-G-T-Y-S-L-P-K-S-E-F-V-V-P-H-L-E-L-P-S-W-L-T-T-G-N-Y-R-I-E-S-I-L-S-N-R-G-K-R-L-G-C-I-K-I-A-A-S-L-K-G-V"} +{"text": "### FUNCTION Crystallins are the dominant structural components of the vertebrate eye lens ### SEQUENCE -M-S-G-T-L-S-Q-G-S-S-P-A-R-L-T-L-W-E-E-E-N-F-Q-G-R-R-C-E-L-M-S-D-C-S-S-I-R-E-L-S-G-F-R-R-V-R-S-V-K-V-E-S-G-A-W-V-G-F-E-Y-P-D-F-Q-G-Q-Q-F-I-L-E-K-G-D-Y-P-R-S-T-A-W-S-G-S-S-G-Y-R-T-D-Q-L-L-S-F-R-P-L-L-C-A-N-H-S-D-S-R-V-T-L-Y-E-G-E-N-F-Q-G-C-K-F-E-L-S-D-D-Y-P-S-L-P-A-M-G-W-A-S-K-D-V-G-S-L-K-V-T-S-G-A-W-V-G-Y-Q-Y-P-G-F-R-G-Y-Q-Y-V-L-E-Q-D-R-H-S-G-E-F-R-K-Y-S-E-F-G-T-Q-A-H-T-N-Q-L-Q-S-I-R-R-V-Q-H"} +{"text": "### FUNCTION Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts It also modulates hydroxyapatite crystal formation on the tooth surface ### SEQUENCE -M-K-I-F-F-F-A-F-I-M-A-L-M-V-A-M-I-K-A-D-S-S-E-E-E-H-R-L-R-F-N-P-R-F-Y-Y-P-N-Q-Q-G-G-Y-I-P-S-Y-P-A-Y-P-Y-P-Y-P-Y-P-V-Q"} +{"text": "### FUNCTION Highly potent vasoconstrictor ### SEQUENCE -M-Y-K-L-A-S-C-C-L-L-F-I-G-F-L-N-P-L-F-S-L-P-L-L-D-S-G-E-V-S-L-Q-L-S-A-P-H-E-D-A-P-L-T-S-E-E-L-E-R-A-S-L-L-Q-I-L-P-E-M-L-L-G-A-E-R-G-D-S-L-R-K-A-D-S-S-T-N-I-F-N-P-R-G-N-L-R-K-F-Q-D-F-S-G-Q-D-P-D-I-L-L-S-H-L-L-A-R-I-R-K-P-Y-K-K-R-E-T-P-D-C-F-W-K-Y-C-V"} +{"text": "### FUNCTION May be an effector molecule of cytotoxic activity Has antimicrobial activity ### SEQUENCE -M-T-S-R-A-L-L-L-L-A-S-A-L-L-G-T-P-G-L-T-F-S-G-L-N-P-E-S-Y-D-L-A-T-A-H-L-S-D-G-E-Q-F-C-Q-G-L-T-Q-E-D-L-Q-G-D-L-L-T-E-R-E-R-Q-G-I-A-C-W-S-C-R-K-I-L-Q-K-L-E-D-L-V-G-E-Q-P-N-E-A-T-I-N-E-A-A-S-R-V-C-R-N-L-G-L-L-R-G-A-C-K-K-I-M-R-T-C-L-R-L-I-S-R-D-I-L-A-G-K-K-P-Q-E-V-C-V-D-I-K-L-C-K-H-K-A-G-L-I"} +{"text": "### FUNCTION Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids ### SEQUENCE -M-E-M-L-Q-G-L-L-L-W-L-L-L-N-V-G-G-V-W-A-S-R-G-P-L-R-P-L-C-R-P-I-N-A-T-L-A-A-E-N-E-A-C-P-V-C-V-T-F-T-T-T-I-C-A-G-Y-C-P-S-M-V-R-V-L-P-A-I-L-P-P-M-P-Q-P-V-C-T-Y-H-E-L-H-F-A-S-I-R-L-P-G-C-P-P-G-V-D-P-M-V-S-F-P-V-A-L-S-C-R-C-G-P-C-R-L-S-N-S-D-C-G-G-P-R-A-Q-P-L-A-C-D-R-P-P-L-P-G-L-L-F-L"} +{"text": "### FUNCTION Binds specifically to cytosolic chaperonin ### SEQUENCE -M-S-Q-E-K-I-S-E-I-I-K-D-I-S-A-L-K-T-S-C-E-K-L-N-S-Q-L-D-E-L-I-T-Q-K-V-E-N-E-M-L-L-E-E-V-K-V-L-E-D-D-S-V-L-H-K-L-V-G-L-V-L-V-K-E-E-K-S-K-C-Y-D-T-I-S-R-R-L-Q-Y-I-T-G-E-I-E-N-R-K-K-V-I-T-N-S-E-E-K-L-R-K-L-F-S-D-L-E-A-H-A-G-Q-R-K-I-P-V-P-Q-A"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-K-V-F-K-D-V-F-T-N-D-E-V-C-S-D-S-Y-V-Q-Q-D-P-F-E-V-P-E-F-R-E-I-A-F-E-V-K-S-N-K-R-I-K-G-N-E-D-Y-G-I-A-D-N-S-E-D-A-V-E-G-M-G-A-D-V-E-H-V-I-D-I-V-D-S-F-Q-L-T-S-T-A-F-S-K-K-E-Y-S-A-Y-I-K-N-Y-M-Q-K-V-A-K-Y-L-E-E-K-K-P-D-R-V-E-I-F-K-T-K-A-Q-P-F-I-K-H-I-L-T-N-F-D-D-F-E-F-Y-M-G-E-S-L-D-M-E-A-G-I-I-Y-S-Y-Y-K-G-E-E-I-T-P-R-F-V-Y-I-S-D-G-L-F-E-E-K-Y"} +{"text": "### FUNCTION Probable neurotoxin that inhibits ion channels ### SEQUENCE -M-H-L-S-L-A-R-S-A-V-L-I-L-L-L-L-F-A-L-G-N-F-V-G-V-Q-P-G-Q-I-T-R-D-A-D-H-G-I-N-L-R-S-L-R-K-Q-M-S-R-S-P-L-V-K-G-A-F-C-G-Q-A-C-S-S-V-K-C-P-K-K-C-F-C-H-P-E-E-K-V-C-Y-R-E-M-R-T-K-E-R-D"} +{"text": "### FUNCTION May increase intracellular calcium release through the activation of nuclear inositol 1,4,5-trisphosphate receptors of cardiomyocytes, thereby causing an increase in the contraction frequency of these cells ### SEQUENCE -M-N-T-F-V-V-V-F-L-L-L-T-A-I-L-C-H-A-E-H-A-L-D-E-T-A-R-G-C-N-R-L-N-K-K-C-N-S-D-G-D-C-C-R-Y-G-E-R-C-I-S-T-G-V-N-Y-Y-C-R-P-D-F-G-P"} +{"text": "### FUNCTION Necessary for protein translocation in the endoplasmic reticulum and multi-pass membrane protein biogenesis ### SEQUENCE -M-D-Q-V-M-A-W-V-E-P-G-K-Q-F-A-K-D-S-I-R-L-V-K-R-C-T-K-P-D-R-K-E-F-Q-K-I-A-V-A-T-A-I-G-F-A-I-M-G-F-I-G-F-F-V-K-L-I-H-I-P-I-N-N-I-I-V-G-S"} +{"text": "### FUNCTION Required for ribosome biogenesis Part of a complex which catalyzes pseudouridylation of rRNA This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 Pseudouridine ### SEQUENCE -M-A-K-T-P-K-K-D-K-T-E-E-K-E-E-H-E-E-S-G-G-N-K-E-D-R-E-R-A-Y-E-V-L-A-T-R-V-N-P-I-A-S-P-L-A-A-R-K-L-T-K-R-L-Y-K-T-V-K-K-A-S-K-E-K-N-I-R-K-G-I-R-D-V-Q-K-F-I-K-K-G-E-R-G-I-V-L-I-A-G-D-T-T-P-I-E-V-Y-C-H-L-P-V-V-C-E-D-A-K-I-P-Y-C-Y-V-P-A-K-Q-D-L-G-E-A-A-G-S-K-R-P-T-C-C-V-L-L-K-P-N-E-S-Y-Q-S-S-Y-D-E-C-L-T-D-V-T-T-L-P-R-P-I"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-N-F-R-E-E-R-Y-D-T-I-M-F-T-D-S-H-C-P-R-V-V-A-D-F-F-Y-E-V-E-S-R-F-T-T-A-S-S-K-V-D-G-R-L-I-G-A-N-P-S-G-E-G-E-D-D-E-D-V-D-D-T-S-E-R-V-I-D-L-V-H-A-N-G-F-I-S-V-P-Y-D-L-K-S-Y-K-A-Q-L-K-S-Y-L-K-A-I-K-E-R-L-Q-K-T-V-P-D-K-L-P-L-L-E-S-Q-V-N-K-Y-R-K-D-V-F-A-N-F-D-Q-Y-E-C-F-T-G-P-S-T-N-P-E-A-M-V-V-L-M-N-F-V-C-G-R"} +{"text": "### FUNCTION Not involved in actin polymerisation, instead functions to stimulate nucleotide exchange on monomeric actin and influence turnover of the small amount of cytosolic actin microfilaments Essential for erythrocytic schizogony ### SEQUENCE -M-V-S-G-V-K-V-S-D-E-C-V-Y-E-F-N-K-L-K-I-K-H-I-H-K-Y-I-I-Y-R-I-E-N-Y-E-E-V-I-V-D-F-L-E-Q-D-N-S-L-K-S-Y-K-D-I-I-I-D-I-R-N-N-L-K-T-T-E-C-R-Y-I-I-A-D-M-P-I-P-T-P-E-G-V-L-R-N-R-I-Y-F-I-F-W-S-P-D-L-A-K-S-K-E-K-M-L-Y-A-S-S-K-E-Y-L-V-R-K-I-N-G-I-F-K-S-L-E-I-T-C-D-L-E-D-F-E-D-E-L-R-T-I-I-L-N-T"} +{"text": "### FUNCTION The GINS complex plays an essential role in the initiation of DNA replication ### SEQUENCE -M-T-P-E-Q-C-E-F-I-A-G-N-E-W-I-Q-I-N-P-Q-F-N-L-D-E-L-H-L-I-C-G-D-I-G-P-F-E-A-G-M-P-I-W-V-P-L-W-I-A-V-T-L-R-K-R-R-K-C-T-I-I-P-P-Q-W-L-C-V-E-E-L-K-K-L-V-I-A-E-S-G-T-N-A-F-G-Q-V-P-R-F-Y-L-E-I-A-H-M-F-V-Q-Y-A-K-E-D-L-P-D-S-D-M-I-R-V-Y-V-Q-D-L-W-D-K-R-S-A-K-L-N-N-S-S-T-K-F-L-G-Q-V-E-S-C-H-A-R-M-D-N-I-T-L-M-E-V-A-Y-I-K-R-S-L-I-T-A-S-R-E-I-E-A-L-N-K-S-F-H-E-L-S-S-Q-N-S-S-D-Q-R-Y-V-I-A"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-S-A-S-V-S-S-K-S-T-V-V-S-S-I-I-S-G-L-L-S-I-V-L-F-G-T-L-R-F-C-S-E-W-F-N-D-S-Q-L-R-V-L-L-G-G-Y-L-F-S-W-V-F-I-L-S-L-T-C-V-S-N-A-E-M-V-V-F-G-Q-D-F-Q-A-K-L-L-P-E-I-I-F-C-L-S-L-T-V-A-A-A-G-L-V-H-R-V-C-A-T-T-S-V-L-F-S-L-V-G-L-Y-F-L-N-R-I-S-T-K-Y-Y-S-V-Q-V-P-S-V-D-A-P-T-T-R-K-G-G-K-K-F-K"} +{"text": "### FUNCTION May participate in the coupling of lysosomes to microtubule plus-end-directed kinesin motor ### SEQUENCE -M-S-R-G-N-E-L-V-F-K-A-K-K-T-S-E-K-I-S-E-N-I-H-I-F-A-N-D-P-S-L-A-F-F-R-V-Q-E-H-V-R-K-V-T-P-A-I-F-E-K-R-D-E-V-F-Q-L-Q-N-N-L-Q-G-H-C-Y-D-M-E-Y-G-I-Q-A-L-R-T-I-E-K-S-E-S-I-F-E-N-I-Q-E-M-I-K-A-S-I-F-L-K-Q-Q-L-K-Y-E-E-S-R-K-K-V-K-K-D-S-T-K-S-S-V-Y-K-R-F-S-A-H-L-A-L-D-L-P-D-L-P-D-F-G-G-V-M-R-E-T-S-Q-R-M-E-N-M-I-G-P-G-T-A-T-G-R-T-E-A-Q-A-A-T-S-S-N-P-G-E-L-Q-R-S-Y-T-T-L-H"} +{"text": "### FUNCTION Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA ### SEQUENCE -M-S-L-V-I-P-E-K-F-Q-H-I-L-R-V-M-N-T-N-I-D-G-R-R-K-I-M-F-A-L-T-S-I-K-G-V-G-R-R-Y-S-N-I-V-C-K-K-A-D-I-D-L-S-K-R-A-G-E-L-S-D-E-E-V-E-R-L-I-T-I-M-Q-N-P-R-Q-Y-K-I-P-D-W-F-L-N-R-Q-K-D-V-K-D-G-K-Y-S-Q-V-M-A-N-S-L-D-N-K-L-R-E-D-L-E-R-L-K-K-I-R-A-H-R-G-L-R-H-Y-W-G-L-R-V-R-G-Q-H-T-K-T-T-G-R-R-G-R-T-V-G-V-S-K-K-K"} +{"text": "### FUNCTION Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA ### SEQUENCE -M-A-L-I-I-P-E-K-F-Q-H-I-L-R-V-M-N-T-N-I-D-G-K-R-K-I-M-F-A-M-T-A-I-K-G-M-G-R-R-Y-A-N-V-V-C-K-K-A-D-V-D-I-T-K-R-A-G-E-L-S-E-D-E-I-E-R-V-I-T-I-M-S-N-P-R-Q-Y-K-I-P-N-W-F-L-N-R-Q-K-D-V-K-D-G-K-Y-S-Q-V-M-S-N-A-L-D-N-K-L-R-E-D-L-E-R-L-K-K-I-R-A-H-R-G-L-R-H-Y-W-G-L-R-V-R-G-Q-H-T-K-T-T-G-R-R-G-R-T-V-G-V-A-K-K-K"} +{"text": "### FUNCTION Necessary for the splicing of pre-mRNA ### SEQUENCE -M-A-M-A-N-R-Q-N-R-G-A-K-L-P-P-E-V-N-R-I-L-Y-I-K-N-L-P-Y-K-I-T-T-E-E-M-Y-E-I-F-G-K-F-G-A-V-R-Q-I-R-V-G-N-T-A-E-T-R-G-T-A-F-V-V-Y-E-D-I-F-D-A-K-T-A-C-E-H-L-S-G-Y-N-V-S-N-R-Y-L-V-V-L-Y-Y-Q-A-T-K-A-W-K-R-M-D-T-E-K-A-R-T-K-L-E-D-I-K-E-R-Y-G-I-G-G-D-I-D-K-E-K-E-K-L-G-L-F-T-P-R-R-I"} +{"text": "### FUNCTION May have a role in proliferation and/or differentiation ### SEQUENCE -M-A-D-S-G-D-A-G-S-S-G-P-W-W-K-S-L-T-N-S-R-K-K-S-K-E-A-A-V-G-V-P-P-P-A-Q-P-A-P-G-E-P-T-P-P-A-P-P-S-P-D-W-T-S-S-S-R-E-N-Q-H-P-N-L-L-G-G-A-G-E-P-P-K-P-D-K-L-Y-G-D-K-S-G-S-S-R-R-N-L-K-I-S-R-S-G-R-F-K-E-K-R-K-V-R-A-T-L-L-P-E-A-G-R-S-P-E-E-A-G-F-P-G-D-P-H-E-D-K-Q"} +{"text": "### FUNCTION Tumor-associated antigen ### SEQUENCE -M-T-F-K-G-F-Q-M-N-E-E-K-L-E-I-G-I-Q-D-A-S-S-E-N-C-Q-L-Q-E-S-Q-K-Q-L-L-Q-E-A-E-V-W-K-E-Q-V-S-E-L-N-K-Q-K-I-T-F-E-D-S-K-V-H-A-E-Q-V-L-N-D-K-E-N-H-I-E-T-L-T-E-R-L-L-K-I-K-D-Q-A-A-V-L-E-E-D-I-T-D-D-G-N-L-E-L-E-M-N-S-E-L-K-D-G-A-Y-L-D-N-P-P-K-G-A-L-K-K-L-I-H-A-A-K-L-N-A-S-L-T-T-L-E-G-E-R-N-Q-F-I-F-S-Y-L-K-L-I-K-P-G-R-A"} +{"text": "### FUNCTION May be involved in a redox-related process ### SEQUENCE -M-A-P-R-G-R-K-R-K-A-E-A-A-V-V-A-V-A-E-K-R-E-K-L-A-N-G-G-E-G-M-E-E-A-T-V-V-I-E-H-C-T-S-U-R-V-Y-G-R-N-A-A-A-L-S-Q-A-L-R-L-E-A-P-E-L-P-V-K-V-N-P-T-K-P-R-R-G-S-F-E-V-T-L-L-R-P-D-G-S-S-A-E-L-W-T-G-I-K-K-G-P-P-R-K-L-K-F-P-E-P-Q-E-V-V-E-E-L-K-K-Y-L-S"} +{"text": "### FUNCTION Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH At alkaline ambient pH, activates transcription of alkaline-expressed genes ### SEQUENCE -V-C-E-R-H-V-G-R-K-S-T-N-N-L-N-L-T-C-Q-W-N-S-C-R-T-T-T-V-K-R-D-H-I-T-S-H-I-R-V-H-V-P-L-K-P-H-K-C-E-F-C-G-K-S-F-K-R-P-Q-D-L-K-K-H-V"} +{"text": "### FUNCTION Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH At alkaline ambient pH, activates transcription of alkaline-expressed genes ### SEQUENCE -E-H-V-C-E-R-H-V-G-R-K-S-T-H-N-L-N-L-T-C-Q-W-G-S-C-N-T-T-T-V-K-R-D-H-I-T-S-H-L-R-V-H-V-P-L-K-P-H-K-C-D-F-C-G-K-A-F-K-R-P-Q-D-L-K-K-H-V-K-N-H"} +{"text": "### FUNCTION Necessary for protein translocation in the endoplasmic reticulum ### SEQUENCE -M-D-S-S-V-P-G-G-Q-R-T-L-Q-K-R-R-N-A-Q-L-Q-K-E-K-K-A-N-Q-T-P-A-S-P-R-Q-A-G-F-G-G-S-S-S-S-I-L-K-L-Y-T-D-E-A-N-G-L-R-V-D-P-L-V-V-L-F-L-A-V-A-F-V-F-S-V-V-A-L-H-V-V-A-K-V-S-G-K-I-F"} +{"text": "### FUNCTION Negative regulator of sphingolipid synthesis ### SEQUENCE -M-N-V-G-V-A-H-S-E-V-N-P-N-T-R-V-M-N-S-R-G-I-W-L-T-Y-A-L-G-V-G-M-L-H-I-V-L-L-S-I-P-F-F-S-V-P-V-V-W-T-L-T-N-V-I-H-N-F-G-M-Y-V-F-M-H-A-V-K-G-T-P-F-E-T-P-D-Q-G-K-A-R-L-L-T-H-W-E-Q-L-D-Y-G-V-Q-F-T-S-S-R-K-F-F-T-I-S-P-I-I-L-Y-F-L-A-S-F-Y-T-K-Y-D-T-A-H-F-V-I-N-T-A-S-L-L-S-V-L-I-P-K-L-P-Q-L-H-G-V-R-I-F-G-I-N-K-Y"} +{"text": "### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-C-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-I-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-Y-N-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-S-K-S-G-E-K-F-Q-C-S"} +{"text": "### FUNCTION May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors ### SEQUENCE -M-V-L-D-K-E-E-G-V-P-M-L-S-V-Q-P-K-G-K-Q-K-G-C-A-G-C-N-R-K-I-K-D-R-Y-L-L-K-A-L-D-K-Y-W-H-E-D-C-L-K-C-A-C-C-D-C-R-L-G-E-V-G-S-T-L-Y-T-K-A-N-L-I-L-C-R-R-D-Y-L-R-L-F-G-T-T-G-N-C-A-A-C-S-K-L-I-P-A-F-E-M-V-M-R-A-R-D-N-V-Y-H-L-D-C-F-A-C-Q-L-C-N-Q-R-F-C-V-G-D-K-F-F-L-K-N-N-M-I-L-C-Q-M-D-Y-E-E-G-Q-L-N-G-S-F-E-T-Q-V-Q"} +{"text": "### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-C-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-I-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-S-D-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-S-K-S-G-E-K-Y-Q-C-S"} +{"text": "### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-C-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-I-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-Y-N-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-P-K-S-G-E-K-F-Q-C-S"} +{"text": "### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-C-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-I-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-Y-N-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-S-K-S-G-E-K-S-Q-C-S"} +{"text": "### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-C-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-V-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-Y-N-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-S-K-S-G-E-K-F-Q-C-S"} +{"text": "### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-R-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-I-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-Y-N-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-S-K-S-G-E-K-Y-Q-C-S"} +{"text": "### FUNCTION Induces caspases and apoptosis Counters the protective effect of Bcl-2 ### SEQUENCE -M-E-Q-D-I-Y-S-N-G-S-D-H-M-E-R-M-L-L-F-A-F-L-A-E-S-S-G-C-E-F-Q-E-Q-L-P-S-L-Q-S-Q-G-V-L-C-S-V-K-D-A-L-C-Y-D-S-D-G-E-L-Q-T-D-G-N-R-S-G-H-L-Q-N-G-E-L-V-P-D-P-E-V-N-E-A-I-V-R-T-I-A-A-Q-L-A-E-I-G-D-Q-L-D-K-Q-I-K-A-K-V-V-N-D-L-V-Q-H-F-L-N-E-N-L-P-R-E-E-I-T-R-C-L-S-Q-A-V-E-G-L-A-R-A-I-P-S-D-L-E-Q-E-K-A-M-L-V-L-A-M-L-L-T-K-K-V-A-N-Q-M-P-S-L-L-Q-R-V-F-S-T-T-V-N-Y-I-S-Q-H-F-H-N-Y-I-V-R-M-L-R-E"} +{"text": "### FUNCTION Hypotensive neuropeptide that binds cholecystokinin receptors ### SEQUENCE -M-Y-S-G-I-C-S-C-L-F-L-A-V-L-S-S-S-S-L-G-Q-Q-I-S-G-S-Q-H-A-N-P-A-V-T-D-L-E-Q-S-L-L-E-N-H-R-H-T-R-I-P-T-S-G-R-P-I-Q-L-V-D-G-S-I-D-Q-K-A-N-L-G-A-L-L-A-K-Y-L-Q-Q-A-R-R-G-S-T-G-K-A-S-V-M-G-L-Q-N-F-D-P-T-H-R-I-K-D-R-D-Y-M-G-W-M-D-F-G-R-R-S-A-E-E-Y-E-Y-S-S"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-A-S-Q-Q-M-S-T-N-N-A-Q-M-S-A-Q-Q-A-A-V-L-Q-Q-T-Q-A-Q-Q-L-S-Q-Q-Q-D-F-D-P-V-H-R-F-K-M-L-I-P-P-L-K-D-S-L-Q-N-V-M-T-I-A-S-L-N-F-A-H-N-T-A-I-D-N-G-L-K-T-T-E-K-G-N-D-A-A-V-Q-R-F-D-K-S-L-E-E-F-Y-A-L-C-D-Q-L-E-L-C-L-R-L-A-H-E-C-L-S-Q-S-I-D-S-T-K-H-S-P-N-L-V-P-T-A-T-K-P-D-T-V-Q-T-E-S-L-S-Y-S-Q-Y-L-S-M-I-K-S-Q-I-S-C-A-K-D-I-H-N-A-L-L-E-C-S-K-K-I-A-G-K-G-Q-G-A-C-N"} +{"text": "### FUNCTION Antifreeze proteins lower the blood freezing point ### SEQUENCE -M-K-F-S-L-I-A-A-V-A-L-L-A-L-A-Q-G-S-F-A-Q-D-A-A-D-L-E-K-I-T-Q-Y-F-E-N-L-K-N-K-M-T-E-D-V-T-A-F-L-T-N-Q-D-V-A-N-Q-A-Q-T-F-M-Q-E-R-K-T-Q-L-E-P-L-A-T-Q-I-Q-E-Q-L-R-A-A-A-T-K-F-E-E-H-I-T-P-L-A-A-N-V-Q-P-V-V-E-N-F-Q-Q-Q-M-E-A-L-V-Q-K-L-M-E-K-T-R-S-I-S-N"} +{"text": "### FUNCTION Interferes with one step of hemostasis ### SEQUENCE -M-G-R-F-I-F-V-S-F-G-L-L-V-V-F-L-S-L-S-G-T-A-A-D-C-P-S-G-W-S-S-Y-D-G-H-C-Y-Q-V-F-S-D-L-K-N-W-D-D-A-E-S-F-C-S-G-Q-H-E-G-S-R-L-A-S-I-H-S-R-E-E-E-A-F-V-G-K-M-A-S-R-T-L-K-Y-T-S-M-W-L-G-L-N-N-P-W-K-E-C-K-W-E-W-S-D-D-T-R-L-D-Y-K-V-W-T-R-R-P-Y-C-T-V-M-V-V-K-T-D-R-I-F-W-F-N-R-G-C-E-K-S-V-S-F-V-C-K-F-K-A-Y-S-E-D-A-A-E"} +{"text": "### FUNCTION Virion protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-R-G-C-D-S-I-D-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-F-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V"} +{"text": "### FUNCTION Participates in either intracellular transport of viral proteins or intercellular spread of the virus Cellular profilins modulate actin filament dynamics via direct binding to actin through an actin-binding domain as well as by modulation of other actin-binding proteins In contrast to cellular homologs, the poxvirus profilins seem to bind actin only weakly ### SEQUENCE -M-A-A-E-W-H-K-I-I-E-D-V-S-K-N-N-K-F-E-D-A-A-I-V-D-Y-K-T-K-K-N-V-L-A-A-I-P-N-R-T-F-A-K-I-I-P-G-E-V-I-A-L-I-T-N-R-N-I-L-K-P-R-I-G-Q-K-F-F-I-V-Y-T-N-S-L-M-D-E-N-T-Y-T-M-E-L-L-T-G-Y-A-P-V-S-P-I-V-I-A-R-T-H-T-A-L-I-F-L-M-G-K-P-T-T-S-R-R-E-V-Y-R-T-C-R-D-Y-A-T-N-V-R-A-T-G-N"} +{"text": "### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-N-S-L-S-I-F-F-I-V-V-A-T-A-A-V-C-L-L-F-I-Q-G-Y-S-I-Y-E-N-Y-G-N-I-K-E-F-N-A-T-H-A-A-F-E-Y-S-K-S-I-G-G-T-P-A-L-D-R-R-V-Q-D-V-N-D-T-I-S-D-V-K-Q-K-W-R-C-V-V-Y-P-G-N-G-F-V-S-A-S-I-F-G-F-Q-T-E-V-G-L-N-N-T-R-S-I-R-K-F-N-T-M-Q-Q-C-I-D-F-T-F-S-D-V-I-N-I-D-I-Y-N-P-C-V-A-P-N-I-N-N-A-E-C-Q-F-L-K-S-V-L"} +{"text": "### FUNCTION Has thioltransferase and dehydroascorbate reductase activities ### SEQUENCE -M-A-E-E-F-V-Q-Q-R-L-A-N-N-K-V-T-I-F-V-K-Y-T-C-P-F-C-R-N-A-L-D-I-L-N-K-F-S-F-K-R-G-A-Y-E-I-V-D-I-K-E-F-K-P-E-N-E-L-R-D-Y-F-E-Q-I-T-G-G-K-T-V-P-R-I-F-F-G-K-T-S-I-G-G-Y-S-D-L-L-E-I-D-N-M-D-A-L-G-D-I-L-S-S-I-G-V-L-R-T-C"} +{"text": "### FUNCTION Viral suppressor of RNA silencing which binds specifically to silencing RNAs ### SEQUENCE -M-E-R-A-I-Q-G-S-D-A-R-E-Q-A-Y-S-E-R-W-D-G-G-C-G-G-T-I-T-P-F-K-L-P-D-E-S-P-S-L-I-E-W-R-L-H-N-S-E-E-S-E-D-K-D-N-P-L-G-F-K-E-S-W-S-F-G-K-V-V-F-K-R-Y-L-R-Y-D-G-T-E-A-S-L-H-R-A-L-G-S-W-E-R-D-T-V-N-N-A-A-S-R-F-L-G-F-G-Q-I-G-C-T-Y-C-I-R-F-R-G-S-C-L-T-I-S-G-G-S-R-T-L-Q-R-L-I-E-M-A-I-R-T-K-R-T-M-L-Q-L-T-P-C-E-V-E-G-N-V-S-R-G-S-P-E-G-T-E-A-F-K-E-E-S-E"} +{"text": "### FUNCTION The role of the precursor might be to condense the viral prochromatin for encapsidation by virtue of the two basic domains ### SEQUENCE -M-A-R-L-R-R-A-K-R-T-S-Y-R-R-R-R-R-T-T-R-T-R-T-V-V-T-R-T-A-R-S-T-V-R-R-R-G-G-R-I-V-Y-R-T-S-K-T-T-R-V-G-T-R-R-M-R-G-G-F-L-P-L-L-A-P-I-L-A-A-A-I-G-S-I-P-G-I-V-I-A-A-K-Q-K"} +{"text": "### FUNCTION Plays a role in the inhibition of host immune response Binds specifically to transporters associated with antigen processing , thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes ### SEQUENCE -M-S-S-R-Y-L-A-A-V-D-D-Y-L-H-H-P-S-P-R-Y-Q-A-H-V-D-L-R-R-E-L-R-A-Y-A-D-E-E-R-R-E-A-A-R-A-I-A-H-P-E-R-P-L-L-P-P-P-A-T-Q-A-A-P-P-Q-P-S-T-R-E-A-A-H-P-S-A-P-T-A-A-S-S"} +{"text": "### FUNCTION Inhibits host transcriptional machinery, by producing modifications to the phosphorylation state of the C-terminal domain ### SEQUENCE -M-M-S-H-Q-Q-V-Q-M-D-L-I-L-M-Q-G-I-W-T-S-V-L-K-M-Q-N-Y-S-T-L-L-Q-L-G-S-S-S-S-M-P-Q-R-P-R-L-L-S-R-V-S-Q-R-G-R-L-T-L-N-L-E-S-G-R-W-R-L-S-I-I-I-F-L-E-T-G-T-T-Q-L-V-T-T-I-L-P-S-T-D-Y-L-G-I"} +{"text": "### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-N-A-I-T-I-F-F-I-I-L-S-T-V-A-V-C-I-I-I-F-Q-L-Y-S-I-Y-L-N-Y-D-N-I-K-E-F-N-S-A-H-S-A-F-E-F-S-K-S-V-N-T-L-S-L-D-R-T-I-K-D-P-N-D-D-I-Y-D-P-K-Q-K-W-R-C-V-K-L-D-N-D-Y-V-S-V-S-M-F-G-F-K-S-N-G-S-E-I-R-K-F-K-N-L-E-S-C-I-D-Y-T-F-S-Q-S-T-H-S-D-I-K-N-P-C-I-L-Q-N-G-I-K-S-K-E-C-I-F-L-K-S-M-F"} +{"text": "### FUNCTION May mediate extracellular or intracellular signaling of cortical neurons during forebrain development ### SEQUENCE -M-S-S-A-W-T-L-S-P-E-P-L-P-P-S-T-G-P-P-V-G-A-G-L-D-V-E-Q-R-T-V-F-A-F-V-L-C-L-L-V-V-L-V-L-L-M-V-R-C-V-R-I-L-L-D-P-Y-S-R-M-P-A-S-S-W-T-D-H-K-E-A-L-E-R-G-Q-F-D-Y-A-L-V"} +{"text": "### FUNCTION May be involved in cytochrome c oxidase biogenesis ### SEQUENCE -M-H-P-D-L-S-P-H-L-H-T-E-E-C-N-V-L-I-N-L-L-K-E-C-H-K-N-H-N-I-L-K-F-F-G-H-C-N-D-L-D-R-E-M-R-K-C-L-K-N-E-Y-S-E-R-R-T-R-S-R-E-H-G-A-A-M-R-R-R-L-S-D-P-P-E-E-A-G-R"} +{"text": "### FUNCTION Inhibitor of PPP1CA Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction ### SEQUENCE -M-L-S-S-S-A-A-S-C-T-S-P-N-P-D-T-D-N-P-D-K-K-V-R-W-S-S-E-K-R-R-R-A-S-S-T-D-S-E-S-K-T-H-L-D-I-S-K-L-P-R-S-R-R-P-S-R-L-T-V-K-Y-D-R-G-H-L-Q-R-W-L-E-M-E-Q-W-V-D-A-Q-V-Q-E-L-F-Q-G-Q-A-D-T-S-E-P-E-I-D-L-E-A-L-M-E-L-S-T-D-E-Q-R-T-Q-L-E-A-I-L-Q-D-C-P-G-N-R-E-P-F-I-S-E-L-L-S-Q-L-K-R-L-R-R-L-S-R-P-S-K"} +{"text": "### FUNCTION Has antibacterial activity ### SEQUENCE -M-K-L-L-L-L-T-L-A-A-L-L-L-V-S-Q-L-T-P-G-D-A-Q-K-C-W-N-L-H-G-K-C-R-H-R-C-S-R-K-E-S-V-Y-V-Y-C-T-N-G-K-M-C-C-V-K-P-K-Y-Q-P-K-P-K-P-W-M-F"} +{"text": "### FUNCTION May be essential for the survival of the neurosensory epithelium of the inner ear ### SEQUENCE -M-Q-A-C-M-V-P-G-L-A-L-C-L-L-L-G-S-L-T-E-A-K-P-L-Q-E-Y-D-P-Y-A-E-P-P-A-M-P-Y-W-P-F-S-T-S-D-F-W-N-Y-I-Q-Y-L-Q-T-Q-G-A-Y-P-Q-V-E-D-L-A-R-T-F-F-A-H-F-P-L-G-S-T-L-G-F-H-V-P-Y-Q-E-D"} +{"text": "### FUNCTION May be essential for the survival of the neurosensory epithelium of the inner ear ### SEQUENCE -M-Q-P-C-V-L-W-W-L-A-L-G-L-L-L-G-I-P-A-G-A-K-P-T-P-E-E-A-D-P-N-A-Q-P-P-A-M-P-Y-W-P-F-S-T-S-D-F-W-N-Y-V-Q-Y-F-Q-S-Q-G-A-Y-P-Q-I-E-D-M-A-R-T-F-F-A-H-F-P-L-G-S-T-L-G-F-H-V-P-Y-Q-E-D"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-K-K-N-T-N-F-T-Q-I-N-N-N-F-Y-R-L-V-D-D-L-F-L-K-I-E-D-N-L-N-F-Y-D-D-K-I-D-I-D-Y-E-V-Q-D-Y-V-M-T-I-T-F-L-N-K-S-I-I-V-V-N-K-Q-E-S-L-R-Q-I-W-L-A-T-K-F-N-A-Y-H-F-N-Y-K-I-D-K-W-I-C-N-R-S-N-K-D-F-W-E-I-F-E-K-S-C-S-I-Q-S-N-E-N-L-I-F-T-A-F-K-R-I-K-K"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-K-I-H-P-A-Y-S-Q-I-I-A-T-C-S-C-G-N-I-I-E-I-F-S-T-V-N-V-N-L-N-L-D-I-C-A-K-C-H-P-F-Y-T-G-K-Q-R-I-I-D-T-G-G-R-V-E-R-F-K-K-R-F-K-L-I-K-K-D-T-V"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-T-I-N-N-E-N-L-I-W-I-D-L-E-M-T-G-L-N-S-E-I-H-R-I-I-E-I-A-T-V-I-T-D-T-K-L-N-I-I-S-E-G-P-V-I-A-I-H-Q-K-E-E-H-I-V-I-M-D-E-W-N-T-K-I-H-K-K-N-G-L-I-K-R-V-Q-K-S-I-Y-N-E-S-K-A-E-S-K-T-I-F-F-L-K-K-W-V-P-I-Q-S-S-P-I-C-G-N-S-V-Y-Q-D-R-K-F-L-A-R-Y-M-P-N-L-E-N-Y-F-H-Y-R-C-I-D-V-S-T-I-K-E-L-V-N-R-W-C-P-S-F-K-K-I-K-K-Q-N-H-T-A-L-E-D-I-H-E-S-I-I-E-L-N-F-Y-K-K-I-F-F-D-T-I-K-Y-S-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-I-F-M-I-H-P-D-Y-S-E-K-V-S-V-I-I-E-K-Y-K-K-I-I-H-H-N-S-G-I-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-I-L-L-N-I-E-T-F-P-K-T-I-S-L-L-E-T-D-F-R-F-N-N-A-V-I-R-N-I-I-I-S-V-K-K-A-I-N-E-P-S-P-V-I-K-L-K-E-E-K-K-D-K-K"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-Y-F-R-R-R-K-F-C-R-F-T-A-E-G-I-Q-E-I-D-Y-K-D-I-A-M-L-K-N-Y-I-T-E-N-G-K-I-V-P-S-R-I-T-G-T-R-A-K-F-Q-R-Q-L-S-R-A-I-K-K-A-R-Y-L-A-L-L-P-Y-T-D-Q-H-H"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-V-I-L-L-S-K-I-K-K-L-G-D-S-G-A-I-V-H-V-K-S-G-Y-A-R-N-F-L-I-P-K-G-K-A-I-L-A-S-K-K-N-I-E-S-F-E-A-Q-R-V-E-L-E-K-E-N-I-S-K-L-L-I-A-Q-S-R-A-E-K-I-K-T-I-K-S-I-T-I-P-S-K-V-G-K-E-G-K-I-F-G-S-I-G-I-R-N-I-I-K-E-M-N-L-L-G-I-K-V-N-K-K-E-I-K-L-P-N-G-V-L-R-Q-V-G-E-H-K-V-I-F-Q-P-H-N-E-V-C-E-Y-F-I-V-N-I-I-S-K-K"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-Q-K-H-L-I-N-N-N-I-K-I-R-I-L-D-S-N-I-K-K-N-S-S-F-F-L-P-Q-Y-A-T-P-G-S-S-G-L-D-L-R-A-S-I-K-K-K-I-S-L-P-S-K-E-V-I-L-V-P-T-G-I-A-I-H-I-D-N-P-Y-I-T-A-L-V-L-P-R-S-G-L-G-H-K-N-G-I-I-L-G-N-L-I-G-L-I-D-S-D-Y-Q-G-E-L-M-I-S-L-W-N-R-S-K-N-I-F-F-I-N-P-Y-D-R-I-A-Q-M-I-F-V-P-I-I-R-P-T-F-S-I-V-D-D-F-E-E-T-V-R-F-G-K-G-F-G-H-S-G-V-Q"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-I-V-I-A-F-D-F-G-L-K-N-I-G-V-A-V-G-E-N-I-L-K-K-G-R-A-L-N-K-L-S-A-K-N-G-S-P-D-W-N-N-I-K-N-L-L-K-I-W-Q-P-K-F-L-V-V-G-L-P-L-N-I-D-G-T-R-Q-D-I-T-K-K-A-E-K-F-A-F-L-L-K-Y-K-F-N-I-F-V-Y-L-H-D-E-R-L-S-T-K-E-A-K-S-L-I-F-K-K-N-G-F-K-V-L-K-K-E-K-I-H-S-V-A-A-V-I-I-L-E-S-W-F-N-Q-N-L-Y"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-S-R-G-V-N-K-V-I-L-I-G-H-L-G-Q-D-P-E-V-R-Y-M-P-N-G-N-A-V-V-N-M-T-L-A-T-S-E-N-W-K-D-K-N-T-G-E-N-K-E-K-T-E-W-H-R-I-V-L-F-G-K-L-A-E-I-A-G-E-Y-L-R-K-G-S-Q-V-Y-I-E-G-S-L-Q-T-R-K-W-Q-D-Q-N-G-L-E-R-Y-T-T-E-V-I-V-N-I-G-G-T-M-Q-M-L-G-N-R-N-S-N-S-H-N-V-T-L-N-E-N-N-N-I-V-K-T-K-K-I-E-I-N-N-S-P-K-K-I-E-K-I-D-S-S-E-I-D-F-D-D-E-I-P-F"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-N-I-S-D-K-A-Q-N-H-F-I-S-L-L-S-K-E-P-I-G-T-Q-I-R-V-F-I-I-N-P-G-T-Q-N-A-E-C-G-V-A-Y-C-T-E-D-D-V-E-N-H-D-I-K-L-N-Y-N-H-F-F-V-Y-V-D-R-S-I-I-S-F-L-K-N-S-E-I-D-L-I-V-D-N-V-G-S-Q-L-T-F-K-A-P-Y-A-K-Q-N-Y-S-K-N-T-A-S-S-L-K-E-R-I-E-N-F-L-N-N-N-I-N-P-Q-L-S-M-H-G-G-K-V-H-L-I-Q-I-S-Q-N-N-T-A-L-I-K-F-T-G-G-C-N-G-C-S-M-I-G-T-T-L-K-E-I-V-E-K-K-I-L-S-F-F-P-E-I-K-K-V-I-D-Q-T-D-H-L-H-G-N-H-S-F-Y"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-N-Y-T-V-L-V-T-G-S-A-Y-G-T-Q-N-A-S-T-A-F-L-F-C-Q-S-L-I-K-M-S-H-I-L-N-S-V-F-F-Y-C-D-G-V-L-N-A-N-N-F-N-K-P-S-V-D-E-F-D-L-L-S-A-W-K-Q-L-N-E-K-N-K-V-K-L-Y-V-C-V-S-A-A-S-R-R-G-V-I-E-D-E-K-I-S-N-T-K-I-K-N-G-N-F-A-S-F-F-Q-S-S-G-L-L-E-L-A-Y-S-I-K-I-S-D-R-I-I-Q-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-E-K-I-A-F-V-F-S-H-A-P-H-G-T-S-F-G-K-E-G-L-D-V-I-L-G-V-S-S-I-I-K-K-I-S-L-F-F-I-G-D-G-V-L-Q-I-L-K-H-S-K-S-E-N-I-L-A-R-N-Y-T-S-S-F-R-I-L-S-I-Y-D-I-K-N-F-Y-C-C-K-S-S-L-I-D-R-G-L-Y-S-H-N-Q-F-I-L-K-V-N-I-L-N-S-Y-F-F-R-I-K-L-D-D-H-D-A-I-I-N-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-L-H-T-L-M-K-S-P-F-E-T-N-I-S-F-F-S-G-M-L-K-K-T-D-D-F-L-A-L-Q-D-G-V-L-I-A-L-I-D-N-I-F-L-K-K-I-T-F-S-S-E-N-L-Y-V-I-K-E-D-V-Y-A-R-G-I-H-K-N-I-S-S-S-F-I-L-I-S-Y-I-D-F-V-N-L-T-L-K-N-K-K-Q-I-I-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-V-N-Q-L-V-R-K-P-R-L-R-K-I-V-K-T-N-V-P-A-L-E-G-S-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-T-A-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-I-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-S-L-D-C-A-G-V-K-E-R-K-K-G-R-S-K-Y-G-V-K-K-A-K-V"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-R-I-R-I-R-L-K-A-F-D-H-R-L-I-D-Q-S-T-A-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-R-F-T-I-L-I-S-P-H-V-N-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-L-I-D-I-V-E-P-T-E-K-T-V-D-A-L-M-R-L-D-L-A-A-G-V-D-V-Q-I-S-L-G"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-S-Q-E-R-F-L-K-V-L-L-S-P-H-I-S-E-K-S-S-I-S-M-E-K-F-N-T-V-V-L-K-V-S-R-N-T-T-K-N-E-I-K-F-A-V-Q-N-L-F-N-I-Q-V-E-S-V-K-T-V-Y-V-K-G-K-K-K-R-Q-S-N-R-I-I-Y-R-S-D-W-K-K-A-Y-I-K-V-K-K-G-Q-N-L-D-F-M-S-N-I-E"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-V-S-L-L-K-K-V-E-K-A-V-K-I-N-D-K-K-P-L-K-T-W-S-R-R-S-T-V-F-P-N-M-V-G-L-T-I-S-V-H-N-G-R-H-H-I-P-I-F-I-T-E-E-M-V-G-H-K-L-G-E-F-S-L-T-R-T-Y-R-G-H-T-A-D-K-K-V-K-K-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-L-A-Q-H-R-Q-A-R-C-S-A-Q-K-I-R-L-I-A-D-L-I-R-G-K-K-V-P-K-A-L-N-I-L-N-F-N-N-K-K-A-A-I-L-V-K-K-V-L-E-S-A-L-A-N-A-E-H-N-D-G-L-D-V-D-Q-L-R-I-K-N-I-F-V-D-E-G-S-T-M-K-R-M-M-P-R-A-K-G-R-A-D-R-I-L-K-R-T-S-H-I-T-V-I-V-S-D-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-M-H-K-G-R-N-R-G-L-A-F-G-A-N-V-S-F-G-L-F-G-L-K-A-I-D-R-G-R-L-T-A-R-Q-I-E-S-A-R-R-A-I-T-R-Y-I-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-Q-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-I-L-Y-E-M-D-G-V-S-E-E-E-S-R-E-A-F-K-L-A-A-A-K-L-P-I-K-T-T-F-V-T-K-M-V-M"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-K-E-K-I-R-T-L-Q-G-R-V-T-S-N-K-M-N-K-S-A-V-V-A-I-E-R-F-V-K-H-P-I-Y-G-K-F-V-K-K-T-T-K-L-H-I-H-D-E-K-N-E-C-S-I-G-D-L-I-E-I-R-E-S-R-P-I-S-K-T-K-S-W-I-L-V-K-I-L-E-K-N-I-F"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-E-Q-T-I-L-N-V-A-D-N-S-G-A-R-S-A-M-C-I-K-V-L-G-G-S-R-R-R-Y-A-R-I-G-D-I-I-K-I-T-I-K-E-A-I-P-R-G-K-V-K-K-G-E-V-L-K-A-V-V-V-R-T-K-K-G-V-R-R-S-D-G-S-I-I-R-F-D-N-N-A-C-V-V-L-N-N-N-E-Q-P-V-G-T-R-I-F-G-P-V-T-R-E-L-R-I-E-K-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-L-K-L-R-R-N-D-E-I-I-I-L-T-G-K-D-K-G-K-K-G-I-I-K-N-I-L-S-S-N-K-A-I-V-N-G-L-N-L-V-K-K-H-Q-K-P-L-P-S-Q-N-K-N-G-G-I-L-E-K-E-A-P-I-Q-I-S-N-I-A-I-F-N-P-E-L-K-K-A-D-R-I-G-F-R-F-E-E-G-K-K-V-R-F-F-K-S-N-K-K-T-I-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-T-F-Y-D-Y-Y-K-S-K-I-V-K-K-L-M-M-E-L-N-Y-S-S-I-M-Q-V-P-K-I-D-K-I-T-L-N-M-G-V-G-A-A-S-S-D-K-K-V-L-D-N-A-V-L-D-L-T-A-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-V-A-G-F-K-I-R-Q-G-Y-P-I-G-C-K-V-T-L-R-G-K-R-K-W-D-F-F-E-R-L-I-V-I-A-I-P-R-I-R-D-F-R-G-L-S-T-N-S-F-D-G-K-G-N-Y-S-L-G-I-R-E-Q-I-I-F-P-E-I-D-Y-D-K-I-D-R-V-R-G-L-D-I-T-I-T-T-T-A-N-S-D-H-E-A-R-L-L-L-S-S-F-N-F-P-F-R-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-E-V-K-R-V-K-L-A-N-K-F-Y-A-Q-R-I-A-L-K-N-T-I-T-N-L-K-L-S-E-E-E-R-W-D-A-V-L-K-L-Q-I-F-P-R-D-S-S-P-S-R-Q-R-N-R-C-R-Q-T-G-R-P-H-A-F-L-R-K-F-G-L-S-R-I-K-V-R-E-A-A-M-K-G-E-I-P-G-L-K-K-A-S-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-R-P-I-L-I-P-E-G-I-K-I-E-L-N-L-Q-S-I-S-I-K-G-K-Y-G-Y-L-S-R-I-I-H-D-A-V-K-V-E-C-L-N-N-K-I-T-F-S-I-R-S-G-F-S-D-A-W-A-Q-A-G-T-S-R-A-L-V-N-S-M-I-I-G-V-S-K-K-F-S-K-K-L-Q-F-S-G-V-G-Y-R-V-S-L-T-K-G-N-I-V-N-M-S-L-G-Y-S-H-P-I-V-Y-S-L-P-P-Y-I-E-A-E-N-P-S-P-T-E-I-V-I-K-G-V-D-K-Q-L-V-G-Q-I-A-A-N-L-R-S-Y-R-R-P-E-P-Y-K-G-K-G-I-R-Y-S-N-E-V-V-H-M-K-E-A-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-M-F-Y-R-N-K-K-I-I-S-R-T-R-R-L-L-K-A-R-C-K-I-K-S-L-G-A-I-R-L-V-V-H-R-T-S-R-H-M-Y-A-Q-I-I-S-S-E-S-K-V-L-A-F-A-S-T-L-E-S-K-I-K-S-D-L-K-Y-T-G-N-K-E-A-A-E-I-V-G-K-I-I-A-K-R-A-L-L-K-G-I-S-N-V-S-F-D-R-S-G-F-K-Y-H-G-R-I-K-K-L-A-D-S-A-R-N-F-G-L-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-N-I-E-K-K-N-N-S-E-L-Q-E-K-L-I-T-V-N-R-V-S-K-T-V-K-G-G-R-I-F-S-F-T-A-L-T-V-V-G-N-G-E-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-N-M-V-T-I-P-L-V-N-K-T-L-Q-H-S-L-K-G-S-H-T-G-S-N-I-F-M-K-P-A-S-D-G-T-G-I-I-A-G-G-A-M-R-A-V-L-E-V-A-G-I-H-N-V-L-A-K-T-Y-G-S-T-N-P-I-N-V-V-R-A-T-M-N-G-L-T-N-M-K-S-P-E-M-I-A-A-K-R-N-K-L-I-E-D-I-L-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-S-P-S-L-G-S-R-K-N-H-K-R-L-G-R-G-I-G-S-G-F-G-K-T-A-G-R-G-H-K-G-Q-K-S-R-S-G-G-H-V-N-R-G-F-E-G-G-Q-M-P-I-Y-R-R-I-P-K-F-G-F-N-S-R-K-K-N-I-T-A-E-V-R-L-S-D-I-S-K-L-S-T-D-I-I-D-L-K-V-L-K-K-E-N-I-I-N-K-N-I-K-Y-V-K-I-I-L-S-G-K-L-E-V-A-L-T-L-H-G-L-R-V-T-R-G-A-R-L-A-I-E-N-Y-G-G-K-I-E-G"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-E-H-K-H-A-L-I-A-L-T-S-I-Y-G-I-G-K-K-R-S-K-I-I-C-F-N-A-N-I-A-E-N-S-K-I-S-D-L-K-E-E-E-I-E-L-L-R-E-N-V-A-K-Y-V-T-E-G-D-L-R-R-E-K-T-L-N-I-K-R-L-I-D-L-N-C-Y-R-G-L-R-H-R-R-S-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-C-K-G-P-R-K-A-I-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-V-K-N-S-S-V-R-T-R-K-R-V-K-K-Q-I-T-D-G-I-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-G-W-A-T-S-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-I-A-A-E-R-C-A-E-I-V-K-D-Y-G-I-K-N-L-E-V-M-V-K-G-P-G-P-G-R-E-S-T-I-R-A-L-N-A-A-G-F-R-I-T-N-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-V-L-K-I-L-H-Y-P-D-Q-R-L-R-L-I-A-K-P-V-E-K-I-T-K-E-I-Y-K-I-T-N-N-M-I-D-T-M-Y-Q-E-E-G-I-G-L-A-A-T-Q-V-N-I-Q-L-Q-I-I-V-I-H-K-I-H-A-I-E-K-N-L-I-L-I-N-P-K-I-I-E-K-K-G-S-I-S-I-E-E-G-C-L-S-I-P-E-Y-R-A-F-V-P-R-F-N-Y-I-K-I-Q-A-I-N-L-N-G-N-T-V-E-I-E-A-D-S-I-L-S-I-C-I-Q-H-E-I-D-H-L-N-G-K-L-F-I-D-Y-L-S-E-L-K-R-E-R-I-L-K-K-L-I-K-L-K-K-R-I-K"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-T-K-G-G-L-G-N-L-M-K-Q-A-Q-Q-M-Q-E-K-M-A-K-V-Q-E-E-I-A-K-M-E-V-T-G-E-A-G-A-G-L-V-K-V-T-I-N-G-A-H-N-C-R-R-V-E-V-D-P-S-L-L-K-D-D-K-D-M-L-E-D-L-A-A-A-A-F-N-D-A-T-R-R-I-S-E-V-Q-K-K-K-M-S-A-I-S-T-G-M-Q-L-P-T-G-F-N-I-P-I"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-K-S-N-S-V-L-I-P-M-V-V-E-Q-H-S-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-E-R-I-I-F-I-T-G-T-I-E-D-N-M-A-S-S-I-V-A-Q-M-L-F-L-E-A-E-S-L-D-K-D-I-F-L-Y-I-N-S-P-G-G-I-I-T-S-G-M-S-I-Y-D-T-M-Q-F-I-K-P-D-V-N-T-I-C-I-G-Q-A-C-S-M-A-A-F-L-L-S-S-G-T-K-G-K-R-S-C-L-P-N-A-R-I-M-I-H-Q-P-L-G-G-Y-Q-G-Q-A-S-D-I-A-I-H-A-E-E-I-N-K-M-K-K-K-L-N-K-L-M-S-L-N-T-G-Q-S-I-K-K-I-N-K-D-T-E-R-D-C-F-L-S-A-H-E-S-I-K-Y-G-L-I-D-L-I-L-T-Q-R"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine ### SEQUENCE -M-L-K-N-N-H-T-K-K-L-Y-E-K-I-E-K-D-T-E-G-Y-L-K-K-A-A-D-W-S-I-E-L-A-K-E-I-A-K-K-E-K-I-V-L-T-N-D-H-W-T-V-I-N-F-I-R-K-F-Y-F-K-F-N-I-T-P-S-M-R-M-L-I-K-S-I-E-K-K-I-G-L-K-K-S-N-S-I-Y-L-F-R-L-F-P-E-G-P-A-K-Q-A-S-K-I-A-G-I-P-K-P-S-R-C-L"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-I-I-K-P-N-F-R-R-K-A-R-A-C-A-L-Q-M-L-Y-S-W-E-I-S-Q-N-N-I-K-D-S-A-I-E-F-L-K-E-K-N-K-K-N-I-D-I-I-Y-F-Y-E-L-I-I-G-I-T-Y-N-C-R-S-I-D-D-L-M-K-P-Y-L-S-R-S-L-K-E-L-G-Q-I-E-K-A-I-L-R-I-S-F-Y-E-L-Y-K-R-K-D-I-P-Y-K-V-S-I-N-E-G-I-E-L-A-K-L-F-G-S-E-D-S-H-K-F-I-N-G-V-L-D-K-A-A-L-K-I-K-R"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-K-K-K-N-N-I-I-L-T-I-Q-K-N-C-K-N-T-K-N-I-P-K-K-Y-I-F-E-K-W-I-K-K-V-L-Y-K-K-K-N-V-N-L-I-N-I-R-I-V-D-E-R-E-M-K-N-I-N-L-K-Y-R-G-K-N-K-S-T-N-I-L-S-F-K-F-D-L-F-I-N-K-N-Q-T-L-L-G-D-L-V-L-C-K-K-I-I-E-K-E-S-L-K-Y-Q-K-T-L-E-S-R-W-A-H-M-I-I-H-G-T-L-H-L-L-G-Y-D-H-K-N-K-K-E-K-K-I-M-E-K-I-E-N-K-I-M-L-F-L-N-Y-E-K-P-Y-F-M-K-S-S"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly extracellular ### SEQUENCE -M-K-M-L-K-I-F-L-L-F-L-L-F-W-L-Q-C-S-L-W-I-G-K-N-G-I-L-D-Y-I-K-I-Y-K-K-I-I-V-Q-K-K-K-N-E-D-F-Q-I-R-N-N-Q-L-I-L-E-I-E-R-L-N-N-A-I-K-N"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-I-I-G-D-E-I-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-V-N-A-P-K-E-V-S-V-H-R-E-E-I-Y-Q-R-I-Q-A-E-K-K-Q-K-K-S"} +{"text": "### FUNCTION Activates ribosomal RNA transcription Plays a direct role in upstream activation of rRNA promoters ### SEQUENCE -M-S-E-E-S-M-D-T-G-F-L-V-I-N-T-K-D-K-Q-D-K-T-V-K-K-P-L-R-I-L-I-K-K-S-L-E-N-Y-F-L-H-L-D-K-S-Q-C-V-S-N-L-Y-Q-L-V-L-S-E-L-E-Q-P-L-L-D-I-I-M-Q-H-T-R-G-N-Q-T-R-A-A-S-I-M-G-I-N-R-S-T-L-R-K-K-L-K-R-Y-G-M-N"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-T-N-I-I-Q-E-I-E-Q-E-Q-L-K-E-N-I-P-H-F-R-P-G-D-T-V-E-V-K-V-W-V-I-E-G-S-K-K-R-L-Q-S-F-E-G-I-V-I-S-I-K-N-R-S-L-N-S-S-F-T-V-R-K-V-S-N-G-E-G-I-E-R-V-F-Q-T-H-S-Y-S-I-D-S-I-F-V-K-R-K-G-K-V-R-K-A-K-L-Y-Y-L-R-T-R-T-G-K-S-A-R-I-K-E-R-I-E"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-N-I-F-L-K-K-P-L-H-P-I-L-I-G-K-I-G-K-A-Y-G-I-L-G-W-V-K-F-F-S-F-T-E-N-K-E-K-I-F-S-Y-F-P-W-F-I-L-K-K-K-W-E-I-I-H-V-D-K-W-K-K-H-N-N-N-F-I-I-H-I-E-N-I-L-D-R-S-T-V-S-K-F-T-N-L-E-I-F-I-D-K-S-I-L-P-I-L-K-E-D-E-Y-Y-W-N-D-V-I-D-C-K-V-F-N-S-R-K-E-Y-L-G-K-V-I-N-L-I-R-N-Q-N-N-D-V-L-I-I-R-N-N-L-K-K-N-N-F-K-K-I-M-I-P-F-I-H-K-K-I-V-K-Y-I-N-V-K-H-K-I-I-T-V-I-W-N"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-S-L-K-L-N-D-I-K-R-N-W-F-Y-V-D-A-T-N-K-I-L-G-R-F-A-S-A-I-S-I-R-L-R-G-K-H-K-I-E-Y-T-P-H-L-D-T-G-D-Y-I-I-V-L-N-A-S-K-I-L-V-T-G-Q-K-K-I-N-K-V-Y-Y-H-H-T-G-Y-I-G-G-I-K-Q-L-R-F-E-E-I-M-L-K-N-P-A-K-V-I-E-I-A-V-K-G-M-L-P-K-G-S-L-G-R-S-M-F-K-K-L-K-V-F-S-N-E-N-H-D-H-I-A-Q-C-P-Q-F-L-N-I"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-M-S-G-G-K-Q-Y-R-V-K-K-N-Q-I-I-Q-L-E-K-L-N-N-S-P-G-S-I-I-E-F-D-K-I-L-M-I-S-A-K-K-E-V-K-I-G-E-P-F-L-K-G-T-K-I-K-A-H-V-E-N-H-G-R-L-K-K-I-K-I-I-K-F-N-R-R-K-H-Y-K-K-K-Q-G-H-R-Q-Y-F-T-N-V-K-I-L-D-I-N-N-F-N-G-K"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-I-N-L-I-P-M-T-V-R-G-A-E-K-L-R-E-E-L-E-Q-L-K-N-V-K-R-P-R-I-T-V-Q-I-A-E-A-R-K-H-G-D-L-K-E-N-A-E-Y-H-S-A-R-E-E-Q-S-F-C-E-G-R-I-Q-E-I-E-S-K-L-S-N-S-Q-I-I-D-I-T-K-I-S-N-D-G-R-V-V-F-G-S-T-V-T-I-L-N-I-K-N-N-A-V-F-T-Y-Q-I-V-G-D-D-E-S-D-F-K-K-N-L-I-S-I-N-S-P-M-S-R-G-L-I-G-K-T-V-N-T-I-A-I-I-H-T-P-S-G-N-V-K-Y-K-I-L-K-I-D-Y-I"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-Y-L-F-F-L-I-F-L-I-F-I-S-F-S-L-I-F-L-I-L-L-Q-S-G-K-G-F-N-N-T-I-H-L-N-T-S-N-N-F-N-F-F-N-S-V-G-S-G-G-F-I-K-N-I-I-G-F-F-A-G-F-F-L-I-F-S-I-I-L-C-N-I-N-D-K-K-V-N-S-D-V-F-L-E-K-N-T-Q-K-K-T-I-N-E-K-K-E-Q-K-I-L-N-S-E-L-P-L"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-D-K-L-F-N-R-S-F-R-I-A-Q-E-L-Q-K-N-I-A-F-I-I-Q-H-S-L-K-D-P-R-I-K-T-I-I-T-V-S-E-V-R-L-S-K-D-L-S-Y-A-Q-V-F-V-S-F-L-E-T-N-S-N-L-T-V-K-K-V-L-I-L-L-N-R-A-S-G-Y-I-R-K-L-L-C-K-K-M-N-L-R-I-I-P-I-I-V-F-F-H-D-D-S-F-F-K-G-N-K-I-S-K-L-L-N-I-L-T-E-K-N-N-I-T-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-G-I-M-T-I-K-E-T-I-L-K-Y-G-K-N-E-K-N-T-G-K-T-D-V-Q-I-A-L-L-T-N-Q-I-N-H-L-Q-L-H-F-S-Q-H-K-K-D-H-C-S-R-R-G-L-L-K-M-V-S-K-R-R-K-L-L-N-Y-L-K-K-K-N-I-S-C-Y-T-K-L-I-E-S-L-N-L-R-R"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-Q-I-N-K-L-Q-V-E-A-I-K-S-G-S-V-I-D-H-I-P-A-H-I-G-F-K-L-L-S-L-F-R-F-T-E-T-E-K-R-I-T-I-G-L-N-L-P-S-Q-K-L-D-K-K-D-I-I-K-I-E-N-T-F-L-S-D-D-Q-I-N-Q-L-A-I-Y-A-P-C-A-T-V-N-Y-I-E-K-Y-N-L-V-G-K-I-F-P-S-L-P-K-K-I-D-R-I-L-I-C-P-N-S-N-C-A-S-H-N-H-F-I-T-S-S-F-I-F-T-K-D-I-N-N-E-I-N-L-K-C-Q-Y-C-E-K-E-F-A-K-N-I-V-L"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-N-N-V-E-K-K-I-K-K-I-I-S-K-I-L-N-I-K-V-E-K-I-L-N-N-A-S-F-L-D-D-L-S-A-D-S-L-D-I-V-E-L-I-M-A-I-E-E-E-F-D-I-E-I-S-D-E-D-A-E-K-L-N-T-V-Q-K-S-I-D-Y-I-N-N-K-N-K-K"} +{"text": "### FUNCTION Structural component of flagellum, the bacterial motility apparatus Part of the rod structure of flagellar basal body ### SEQUENCE -M-F-D-K-I-N-K-T-L-D-F-N-Q-N-L-L-N-L-Y-A-K-R-Q-E-I-L-S-S-N-I-A-N-A-D-T-P-N-Y-K-A-M-D-I-N-F-K-D-E-M-D-K-I-T-K-K-S-N-L-D-I-T-L-T-K-T-S-S-H-H-L-N-P-R-K-K-N-F-F-I-F-E-V-K-P-I-T-S-K-E-I-Q-S-N-G-N-T-V-D-M-N-R-E-R-I-E-F-I-K-N-T-L-K-Y-E-E-N-L-V-F-I-K-N-E-I-K-N-I-M-N-V-L-K-G"} +{"text": "### FUNCTION Required for the efficient initiation of filament assembly ### SEQUENCE -M-K-K-L-I-N-I-I-K-D-I-K-E-N-L-M-S-L-Q-N-L-M-H-Q-E-Y-D-N-L-L-K-S-K-I-N-I-K-K-I-K-L-I-I-E-E-K-E-F-F-L-R-K-I-A-S-L-K-K-E-K-S-F-L-E-K-R-Y-N-I-F-P-P-Y-L-Q-F-N-E-L-N-L-H-W-D-E-I-I-S-I-C-F-L-L-K-K-K-N-I-K-N-K-I-I-L-N-E-K-F-Y-L-N-Q-R-F-L-N-T-F-Q-K-Y-R-L-N-Q-N-N-T-T-Y-G-V-D-G-H-L-E-N"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-A-L-L-D-F-F-L-S-R-N-K-N-T-A-H-V-A-K-E-R-L-Q-I-I-V-A-E-Q-R-K-F-K-S-E-P-D-Y-L-P-Q-L-K-R-E-I-L-S-V-I-C-K-Y-V-N-I-D-P-H-M-V-T-I-Q-L-E-Q-K-N-E-D-I-S-V-L-E-L-N-I-I-L-P-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-T-K-E-D-N-I-E-M-Q-G-I-V-I-D-T-L-P-N-T-M-F-R-V-E-L-E-N-K-H-V-I-T-A-H-I-S-G-K-M-R-K-N-Y-I-R-I-L-T-G-D-K-V-T-I-E-L-T-P-Y-D-L-T-K-G-R-I-I-F-R-S-R"} +{"text": "### FUNCTION Low-potential electron donor to a number of redox enzymes ### SEQUENCE -M-K-K-I-G-I-F-F-G-S-D-T-G-N-T-E-K-A-A-E-L-I-H-K-K-I-G-S-N-I-S-M-L-Y-D-I-S-N-V-S-K-K-D-F-E-S-F-D-H-L-I-L-G-V-P-T-W-Y-Y-G-E-I-Q-C-D-W-D-D-F-L-P-I-L-K-K-I-N-F-L-H-K-T-V-A-L-F-G-C-G-D-Q-E-D-Y-A-E-Y-F-C-D-A-L-G-L-I-Y-Q-V-L-K-K-N-N-A-K-I-V-G-K-W-P-T-I-E-Y-N-F-E-S-Y-K-A-L-L-N-K-D-Y-F-V-G-L-V-L-D-E-A-R-Q-P-E-K-T-E"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-S-I-I-G-I-G-T-D-I-I-E-I-F-R-I-K-N-I-V-Y-N-F-K-D-K-L-A-E-R-I-L-S-V-Q-E-L-E-K-Y-K-V-N-K-N-P-I-K-F-L-A-K-R-F-A-V-K-E-A-A-S-K-A-L-G-T-G-I-S-Y-G-I-K-F-N-Q-I-E-L-Y-N-N-N-L-G-K-P-K-L-R-F-L-K-Y-A-L-Q-K-S-E-E-M-K-C-K-S-I-F-V-S-I-S-D-E-K-L-Y-A-C-A-L-V-I-L-E-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-Y-K-K-K-R-C-L-K-S-S-I-I-C-K-N-K-K-A-Y-Y-N-Y-F-I-E-E-V-F-Q-S-G-L-V-L-M-G-W-E-V-K-S-I-R-L-G-Q-V-N-I-I-E-S-Y-I-N-N-D-N-L-N-E-M-Y-L-Y-N-S-I-V-Q-P-L-H-T-S-S-N-Y-V-S-C-D-S-S-R-K-R-K-L-L-L-H-K-N-E-I-Q-Y-L-C-N-K-K-N-K-I-G-S-T-L-V-A-L-S-L-F-W-E-K-S-W-C-K-L-N-F-G-L-A-K-G-K-T-K-I-D-K-R-A-S-E-K-Q-N-E-W-K-K-E-K-L-K-I-L-K-K-V-K-F-Q-N"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-D-I-Y-I-K-S-N-E-K-M-K-V-C-I-N-N-F-Q-I-Q-V-N-N-V-R-T-G-R-A-S-P-E-L-L-N-S-I-Y-V-E-Y-F-G-S-K-V-P-L-R-Q-I-S-N-V-V-V-E-N-Y-H-T-L-K-I-N-I-F-D-D-S-S-T-S-L-I-K-K-A-I-L-N-S-N-L-D-L-N-P-I-L-Y-G-K-D-I-I-V-P-I-P-G-L-T-E-E-R-R-T-H-L-I-K-V-I-R-N-N-A-E-N-A-R-I-Y-I-R-N-I-R-R-D-A-N-D-K-I-K-N-Y-L-K-S-K-I-I-S-E-D-N-E-H-A-A-Q-N-K-I-Q-T-M-T-D-D-Y-I-K-K-I-D-K-I-L-S-E-K-E-K-D-L-M-K-F"} +{"text": "### FUNCTION Transcription factor that acts by binding directly to the RNA polymerase Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters Also required for regulation of fis expression ### SEQUENCE -M-E-K-E-Q-N-K-K-T-S-S-L-N-V-L-A-I-A-G-L-Q-P-Y-Q-K-K-T-D-E-E-Y-M-N-E-K-Q-M-L-H-F-K-K-I-L-E-T-W-K-N-Q-L-T-I-E-I-N-H-T-L-L-Y-I-Q-D-K-S-T-N-F-P-D-P-I-D-R-A-A-Q-E-E-E-F-S-L-E-L-R-N-R-D-R-S-R-K-L-I-K-K-I-Q-E-T-L-K-K-I-K-D-K-D-F-G-Y-C-N-S-C-A-V-E-I-G-I-R-R-L-E-A-R-P-T-A-N-L-C-I-D-C-K-T-L-A-E-I-R-E-K-Q-M-A-G"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-I-V-G-L-S-N-P-K-K-K-Y-H-K-T-R-H-N-V-G-S-W-Y-I-Y-S-L-A-K-N-Y-L-S-I-L-K-E-E-K-K-F-F-G-F-T-G-C-L-N-I-K-S-N-F-I-R-L-L-I-P-D-I-F-M-N-I-N-G-F-S-V-H-R-M-A-S-F-Y-N-I-S-L-N-Q-I-L-I-V-H-D-D-L-D-L-A-P-G-I-I-K-Y-K-Y-S-Y-G-H-S-G-H-N-G-L-R-H-I-I-K-E-F-N-T-K-V-N-F-Y-R-L-R-I-G-I-G-R-P-K-N-K-N-E-I-S-S-F-V-L-S-I-P-D-F-K-E-M-K-L-I-K-K-S-I-S-Y-A-I-K-E-N-F-T-L-L-N-L-I-Q"} +{"text": "### FUNCTION Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters ### SEQUENCE -M-N-V-I-E-K-I-E-R-Q-I-K-D-N-I-I-L-I-Y-M-K-G-T-P-Q-S-P-S-C-G-F-S-A-Q-A-V-Q-A-L-S-I-C-G-E-K-F-A-Y-V-D-I-L-E-N-L-D-I-R-K-E-L-P-R-Y-A-N-W-P-T-F-P-Q-L-W-I-K-G-E-L-I-G-G-C-S-I-I-L-E-M-L-E-N-G-E-L-K-K-I-I-S-N-A-V-L-N-S-K"} +{"text": "### FUNCTION Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ### SEQUENCE -M-S-N-Q-I-V-L-G-M-L-M-I-F-L-F-S-S-C-S-V-L-E-N-K-H-Y-V-L-N-N-N-L-N-E-S-Y-F-N-L-N-K-F-K-K-N-Y-K-G-M-T-K-E-Q-I-I-Y-I-F-G-N-P-I-I-S-D-S-F-N-D-V-F-H-Y-I-I-C-A-E-E-N-G-F-G-C-H-Q-K-I-L-N-I-F-F-K-K-N-K-V-S-K-L-D-I-R"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-D-N-Q-E-K-K-T-N-Y-Q-N-T-D-K-E-N-D-L-E-K-N-K-E-K-K-N-D-E-S-I-F-Q-N-K-K-M-N-E-I-R-E-K-I-F-K-N-K-K-E-I-N-N-L-K-L-R-H-L-A-N-I-E-N-I-K-K-N-T-E-K-K-I-K-K-I-K-N-A-E-I-E-N-F-F-K-Q-I-I-P-I-I-N-N-L-E-D-I-L-T-I-S-T-K-L-N-L-N-D-E-P-S-I-Q-G-I-E-L-T-L-K-S-L-L-S-I-L-I-K-F-G-V-K-I-E-G-K-K-N-E-I-F-N-P-K-I-H-D-V-I-L-T-E-S-S-N-T-I-E-P-N-Y-I-I-S-V-K-K-K-G-F-I-F-K-K-T-I-L-R-K-A-A-V-V-I-S-K-T"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur ### SEQUENCE -M-E-F-V-F-Y-A-C-S-L-I-A-V-I-S-T-L-L-V-I-I-Q-K-N-A-V-Y-S-L-L-Y-L-I-I-S-L-L-S-I-S-G-I-F-F-I-F-G-A-F-F-A-G-A-L-E-V-V-I-Y-A-G-A-I-I-V-L-F-V-F-V-I-M-M-L-N-L-G-K-K-N-D-L-Q-E-K-K-Y-L-N-P-I-F-W-I-G-P-S-F-L-S-L-I-L-F-L-L-M-T-Y-A-I-F-F-V-K-D-K-Q-I-Y-F-S-L-I-D-V-K-E-V-G-I-N-L-F-G-P-Y-L-L-L-V-E-L-S-S-L-L-L-L-S-A-L-V-V-V-F-H-I-G-K-E-K-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-D-S-I-I-S-E-E-R-R-K-K-N-A-S-Q-R-S-K-M-R-T-F-I-K-K-V-R-L-A-I-S-S-G-D-K-E-K-S-Y-D-A-F-K-K-M-Q-P-I-I-D-K-Y-A-T-K-G-L-I-H-K-N-K-A-A-R-Y-K-S-I-L-S-F-K-I-A-K-L-H-K-N"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-F-I-V-K-A-E-I-R-D-K-K-G-K-S-F-S-R-K-L-R-I-E-D-K-F-P-G-V-L-Y-G-F-N-N-T-P-I-S-I-T-M-D-H-N-L-V-F-N-L-Q-K-K-E-D-F-Y-K-E-T-L-C-L-L-I-K-E-K-K-Y-T-V-K-V-H-A-I-Q-R-H-A-F-K-M-K-I-L-H-I-D-F-I-Y-A-K-I"} +{"text": "### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-S-F-F-I-K-D-A-N-A-A-V-N-Q-A-L-E-G-N-S-Y-S-L-I-F-M-L-V-T-F-I-L-I-F-Y-F-M-L-F-R-P-Q-Q-K-K-D-K-E-H-K-N-L-M-N-S-I-A-P-G-D-E-V-M-T-T-S-G-F-L-G-R-V-K-K-V-T-E-N-G-Y-V-L-L-Q-L-N-N-T-T-E-I-F-I-K-K-D-F-I-V-S-S-L-P-K-G-T-L-E-S-L"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-V-V-T-K-A-A-I-S-E-N-L-F-E-K-L-K-L-T-K-R-D-S-K-E-F-V-E-F-F-F-E-E-V-R-K-S-L-E-K-G-E-D-V-K-L-S-G-F-G-N-F-Q-L-K-N-K-K-E-R-P-G-R-N-P-R-T-G-E-N-I-L-I-T-Q-R-R-V-V-I-F-K-A-G-Q-K-L-K-N-R-V-E-H-Y-L-M-K-V-K-Y"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-K-S-Y-F-F-F-I-L-S-N-I-L-I-D-N-F-I-L-V-K-F-L-G-L-C-P-F-I-G-A-S-N-Q-I-K-Q-A-F-G-I-S-F-A-T-S-F-V-V-V-V-S-T-V-L-L-W-F-V-N-F-F-I-L-L-P-F-D-L-V-Y-L-R-I-I-V-Y-M-L-I-I-S-F-G-V-Q-L-I-E-I-I-L-R-G-T-S-P-I-L-Y-R-I-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-A-I-P-L-F-S-L-Y-L-N-H-T-F-L-E-S-I-L-Y-A-V-S-A-S-F-G-F-T-L-V-M-V-I-F-S-S-I-R-E-R-I-L-L-S-D-V-P-L-A-F-Q-G-S-P-I-V-L-I-T-V-S-L-I-S-I-V-F-M-G-F-K-G-L-V-R-I"} +{"text": "### FUNCTION Role in flagellar biosynthesis ### SEQUENCE -M-T-P-E-Y-V-M-G-L-F-H-S-A-M-K-V-T-L-M-L-A-S-P-L-L-L-S-A-L-V-S-G-L-I-I-S-I-L-Q-A-A-T-Q-V-N-E-Q-T-L-S-F-I-P-K-I-I-S-I-L-V-V-I-T-L-L-G-P-W-M-L-G-V-M-L-D-Y-M-H-N-L-F-Y-N-I-P-S-I-I-I-R"} +{"text": "### FUNCTION FliN is one of three proteins ### SEQUENCE -M-K-K-V-E-K-K-D-N-F-K-K-F-K-N-D-N-I-Y-K-K-D-D-K-N-I-N-Q-E-L-I-N-E-E-K-K-I-K-N-F-N-S-S-N-N-E-S-S-N-E-K-K-I-L-F-D-I-E-M-N-I-T-V-E-L-G-K-S-K-V-K-I-K-D-L-L-N-F-S-K-G-S-M-L-F-L-Q-R-K-K-E-D-P-L-K-V-F-A-N-N-K-L-I-A-L-G-E-I-V-F-S-N-N-K-Y-G-I-R-I-I-S-I-N-N-S-L-N-G-I-N-T-S-V"} +{"text": "### FUNCTION Flagellar protein that affects chemotactic events ### SEQUENCE -M-K-Y-K-K-K-I-F-S-I-L-E-N-L-E-K-K-N-I-E-K-D-I-I-N-I-K-N-L-Y-L-Q-K-E-K-Y-V-T-Q-L-S-L-L-K-D-Y-Q-N-E-Y-L-I-K-L-K-S-K-I-E-L-G-I-C-L-Y-Q-W-R-N-Y-N-N-F-I-F-I-L-Y-F-L-I-K-D-N-E-Q-K-I-K-K-N-Q-K-I-L-E-K-S-L-K-Q-Y-S-K-N-Q-I-K-L-K-T-W-N-Y-L-Y-K-K-Y-K-K-K-E-I-K-K-I-L-L-V-E-E-M-I-S-D-E-F-S-Q-L-K-N-L-A-E-G-S-C-Y-N-V"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-F-Q-K-E-I-K-I-N-A-L-H-G-L-H-T-R-P-A-A-E-F-V-K-E-A-K-N-F-I-S-D-I-H-I-I-Y-H-G-K-S-V-N-A-K-S-L-F-K-I-Q-T-L-G-L-V-K-D-S-V-I-I-L-S-A-E-G-E-D-E-K-K-A-V-E-H-L-S-K-I-M-T-E-L-E"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-K-I-R-I-P-D-Q-K-K-A-K-N-L-E-K-I-K-W-F-F-I-T-A-I-F-I-T-S-F-F-I-N-N-F-F-D-K-I-G-Y-F-T-R-I-S-I-I-T-L-L-V-V-F-A-I-S-I-A-L-Y-T-K-K-V-K-N-V-F-V-Y-I-N-A-S-K-N-E-M-K-K-I-T-W-P-Q-Y-K-E-T-L-Y-T-T-F-I-I-I-S-V-T-I-L-I-S-L-L-L-W-G-L-D-S-I-I-F-R-L-I-A-F-I-I-S-V-R-F"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase , probably by partially suppressing pausing In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho May be required to overcome a kinetic limitation of Rho to function at certain terminators Also involved in ribosomal RNA transcriptional antitermination ### SEQUENCE -M-H-E-S-L-K-K-K-W-Y-V-L-Q-A-F-S-G-F-E-S-R-V-A-Q-S-I-K-E-H-V-K-L-N-K-M-N-D-F-F-G-E-V-M-V-P-S-E-E-V-I-E-I-R-G-G-Q-R-R-K-S-E-Y-K-F-F-P-G-Y-V-L-I-H-M-I-M-T-D-S-T-W-H-L-I-R-N-V-P-R-V-L-G-F-I-G-G-K-S-D-K-P-S-P-I-S-D-K-E-V-D-I-I-I-N-R-L-R-Q-I-G-D-K-P-R-P-K-T-L-F-E-P-G-E-M-I-R-V-N-D-G-P-F-A-D-F-N-G-V-V-E-E-V-D-Y-E-K-S-R-L-K-V-S-V-S-I-F-G-R-A-T-P-V-E-L-D-F-R-Q-V-E-K-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-Q-S-Y-I-K-L-Q-V-A-A-G-M-A-N-P-S-P-P-I-G-P-A-L-G-Q-K-G-V-N-I-M-E-F-C-K-L-F-N-K-T-T-E-N-V-E-K-G-L-P-I-P-V-I-V-T-V-Y-S-D-R-S-F-T-F-I-T-K-T-P-P-A-S-V-L-L-K-K-A-A-G-I-K-S-G-S-S-K-P-K-I-E-T-T-G-K-I-T-K-L-Q-I-E-E-I-A-K-T-K-K-N-D-M-T-G-L-N-I-E-S-M-M-R-S-I-E-G-T-A-K-S-M-G-L-I-V-E-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-S-K-K-K-T-I-V-S-K-I-N-Q-I-S-N-L-A-L-S-A-I-I-A-N-S-Q-G-I-S-V-N-K-I-N-E-L-R-K-S-G-R-E-I-G-V-K-M-S-I-V-R-N-T-L-L-S-L-A-I-E-N-T-A-F-K-C-L-K-K-K-L-K-G-S-T-F-I-A-Y-S-T-K-H-P-G-S-G-A-R-L-F-K-E-F-E-K-K-N-K-K-F-K-I-T-G-A-V-F-E-G-K-L-L-S-E-L-E-I-N-Q-L-A-D-M-P-T-Y-E-E-A-I-R-K-L-L-L-T-L-K-I-S-I-A-G-K-L-I-Y-T-L-S-A-I-K-E-K-K-E-T-S"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-Q-L-I-K-I-I-S-K-Q-S-N-L-S-K-I-Q-I-K-S-T-L-E-K-I-L-S-A-I-I-E-S-L-K-K-G-E-S-V-Q-I-V-G-F-G-T-F-K-V-N-S-R-A-S-R-T-G-R-N-P-Q-T-G-K-E-I-I-I-P-A-T-K-V-P-S-F-I-S-G-K-T-L-K-N-A-I-K"} +{"text": "### FUNCTION This protein is required for primosome-dependent normal DNA replication ### SEQUENCE -M-K-I-L-V-S-K-K-I-T-L-D-L-F-C-K-N-P-I-Q-I-I-E-K-E-K-N-E-I-I-S-I-S-K-N-K-K-T-V-F-Y-V-I-Q-P-K-A-L-K-K-L-F-D-I-K-E-Y-F-V-K-S-K-I-T-K-K-E-K-K-I-I-E-K-F-P-M-H-T-N-W-I-P-D-K-D-F-I-Q-K-A-A-L-W-G-I-S-L-N-E-E-V-S-K-Y-E-L-A-S-F-I-S-Y-W-E-A-E-G-L-F-F-H-H-I-Q-W-Q-Q-K-L-A-R-S-L-E-R-S-R-S-M-N-N-A-I-Q-Q-K-K-D-I-T-Y-I-P-V-P-D-Q-K-T-P-D-G-F-R-G-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-R-V-Y-H-S-N-N-F-R-S-G-R-K-I-I-F-E-K-E-P-C-L-I-E-S-S-E-F-V-K-P-G-K-G-Q-S-F-V-R-V-K-L-R-K-L-L-T-K-Q-L-I-E-K-T-F-K-S-T-D-S-L-E-I-A-D-V-S-E-Y-T-L-S-Y-L-Y-N-D-G-H-F-W-Y-F-I-N-N-N-F-E-E-L-S-V-D-K-K-I-V-G-V-N-K-K-W-L-S-E-Q-D-T-C-V-I-T-F-W-N-N-Q-A-I-S-I-T-P-N-I-F-V-E-L-K-V-I-D-T-E-I-A-L-K-S-D-T-I-N-T-T-T-K-L-A-T-L-S-T-G-A-I-L-K-V-P-L-F-I-Q-I-G-S-L-I-K-V-D-T-R-S-G-E-Y-V-S-R-I-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-S-S-D-K-A-F-T-L-D-I-V-T-P-Q-K-L-F-F-S-G-E-I-N-S-V-I-A-P-G-L-N-G-L-F-Q-V-L-K-G-H-A-P-L-L-A-A-L-K-S-G-K-V-R-L-S-L-S-D-R-S-E-D-T-F-Q-I-A-G-G-F-F-E-V-S-G-N-K-A-I-L-L-T-E-E-V-S"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-P-A-S-S-K-S-R-T-S-A-V-P-T-I-E-E-L-I-Q-R-L-E-E-I-T-R-N-I-E-N-P-D-T-G-L-E-N-S-I-A-L-Y-E-E-G-M-S-L-A-E-E-C-R-K-R-L-L-E-T-R-K-K-L-E-T-I-N-P-A-E-T-A-R-P-A-K-P-E-N-A-P-E-S-P-R-M-N-D-L-F-G-T-E-S"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-Q-Q-L-I-R-H-G-R-S-M-K-A-S-K-T-A-S-P-A-L-E-K-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-S-N-K-I-E-V-T-A-Y-I-P-G-E-G-H-N-L-Q-E-H-S-I-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-S-L-D-T-S-G-V-A-D-R-K-Q-S-R-S-K-Y-G-A-K-V-P-K-A-G-A-A-P-A-K-K-K"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-V-Q-Q-K-I-R-I-K-L-K-S-Y-D-H-S-L-V-D-K-W-A-L-K-I-I-D-V-V-K-Q-T-E-A-I-I-F-G-P-I-P-L-P-T-K-T-H-V-Y-T-V-N-R-S-P-H-V-D-K-K-S-R-E-Q-F-A-F-S-S-H-K-R-L-I-E-I-I-N-P-T-A-R-T-I-D-M-L-M-K-L-E-L-P-S-G-V-D-V-E-I-K-S"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-K-N-P-L-L-R-P-W-L-T-E-K-S-T-K-L-T-E-Q-K-G-Q-Y-V-F-Q-V-K-I-D-A-D-K-F-D-I-K-K-A-V-E-E-K-F-G-V-D-V-V-S-I-R-T-I-N-C-L-G-K-S-K-R-Q-Y-T-R-K-G-L-I-A-G-K-K-S-D-W-K-K-A-I-V-T-L-G-D-G-Q-T-I-D-Y-Y-A-K-P-A-E-K-S-E-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-E-F-K-L-E-K-R-I-L-D-M-N-S-K-G-E-K-K-V-V-K-T-W-S-R-S-S-M-I-S-P-D-F-V-G-H-T-V-A-V-H-N-G-K-T-H-V-P-V-Y-V-T-E-N-M-V-G-H-K-L-G-E-F-A-P-T-R-L-F-R-G-H-A-G-G-K-A-E-K-G-G-S-A-P-R-K-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-Q-A-K-A-I-L-R-H-T-P-T-S-P-R-K-M-R-L-V-A-G-L-V-R-G-K-R-V-D-Q-A-K-A-I-L-H-N-S-T-K-S-A-S-R-N-V-M-V-T-L-K-S-A-V-A-N-W-S-Q-L-N-P-D-E-R-L-N-D-N-E-L-F-V-K-A-I-F-V-D-E-G-P-S-L-K-R-L-L-P-A-P-M-G-R-A-Y-R-I-R-K-R-S-N-H-L-T-I-V-V-D-K-V-E-N-K-V-T-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-Q-Y-R-K-T-Q-R-G-R-M-K-G-N-A-Q-R-G-T-A-V-T-F-G-S-F-G-L-K-A-M-E-P-A-W-I-T-S-R-Q-I-E-A-A-R-I-A-M-N-R-Y-M-K-R-D-G-K-I-W-I-R-I-F-P-D-K-P-V-S-K-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-F-W-V-A-V-V-K-P-G-R-V-M-F-E-A-D-G-V-P-R-E-V-A-V-E-A-F-R-L-A-A-K-K-L-P-I-K-T-K-F-I-V-R-P-D-Y-E-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-S-G-A-E-T-R-G-R-K-K-S-W-L-G-K-V-V-S-D-S-M-D-K-G-I-V-V-A-V-E-R-R-V-Q-H-P-V-Y-K-K-Y-F-K-K-T-T-R-L-M-A-H-D-E-N-N-E-A-G-V-G-D-L-V-R-I-T-E-C-R-P-L-S-K-N-K-S-C-R-L-V-E-I-V-E-K-A-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-K-E-T-N-L-V-V-A-D-N-S-G-A-K-K-V-R-C-I-H-V-F-G-G-T-G-R-R-Y-A-A-L-G-D-Q-I-M-V-S-V-K-A-A-V-P-G-G-V-V-K-K-K-D-V-C-K-A-V-V-V-R-C-V-K-E-Q-K-R-K-D-G-S-Y-I-R-F-D-E-N-A-V-V-L-L-N-A-Q-G-E-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-K-R-Y-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-T-G-I-K-K-V-K-L-H-V-R-K-N-D-E-V-T-V-I-A-G-N-D-K-G-K-S-G-K-V-L-K-V-F-P-Q-K-G-R-V-I-V-E-G-V-N-I-R-K-R-H-M-R-P-T-Q-G-M-P-Q-G-A-I-I-E-R-E-F-P-I-H-V-S-N-V-K-K-S"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-P-A-R-L-E-V-Y-Y-R-E-T-V-V-P-K-L-M-E-R-F-K-Y-K-S-I-M-M-V-P-R-L-E-K-I-S-V-N-I-G-V-G-E-A-A-Q-E-P-K-L-L-E-T-A-M-Q-E-L-G-Q-I-T-G-Q-K-P-Q-V-R-K-A-K-K-A-I-S-N-F-K-L-R-E-G-Q-A-I-G-C-R-V-T-L-R-R-K-I-M-F-E-F-M-D-R-F-I-S-V-A-V-P-R-I-R-D-F-R-G-L-S-D-T-S-F-D-G-R-G-N-Y-N-V-G-I-R-E-Q-I-I-F-P-E-I-D-I-D-K-V-P-R-I-N-G-M-D-I-S-F-V-T-S-A-K-T-D-E-E-A-Y-E-L-L-S-L-L-G-M-P-F-K-K-K-N-Q"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-R-K-S-I-I-A-R-N-E-K-R-K-K-L-V-E-K-Y-A-A-K-R-E-E-L-K-A-A-G-D-Y-Q-A-L-S-Q-L-P-R-D-S-S-A-T-R-L-R-T-R-C-V-L-T-G-R-G-R-G-N-Y-R-K-F-G-L-C-R-N-M-F-R-K-L-A-L-E-G-K-L-P-G-V-R-K-A-S-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-M-P-I-R-L-A-D-Q-A-Q-V-E-V-K-E-N-M-I-N-V-T-G-P-K-G-A-L-S-Q-A-L-V-D-E-V-I-V-S-V-A-D-G-A-V-T-V-Q-R-K-D-D-S-K-R-A-R-A-M-H-G-L-Y-R-M-L-V-S-N-M-V-E-G-V-T-K-G-F-T-R-K-L-E-M-S-G-V-G-Y-R-A-E-L-K-G-N-L-L-A-L-T-L-G-Y-S-H-M-I-Y-F-Q-P-P-A-E-I-K-I-E-V-P-D-P-T-T-V-L-V-S-G-I-D-K-A-L-V-G-Q-I-A-A-K-I-R-S-F-R-K-P-E-P-Y-R-G-K-G-I-K-Y-E-G-E-V-I-R-R-K-E-G-K-A-A-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-Q-V-D-K-T-A-R-R-Q-K-I-K-A-R-S-R-A-V-V-R-G-T-Q-E-R-P-R-L-C-V-F-R-S-L-S-Q-I-Y-A-Q-L-I-D-D-E-S-G-K-T-L-M-A-A-S-S-M-S-K-E-N-A-G-L-T-G-T-K-S-E-V-S-A-A-I-G-K-Q-I-A-E-K-A-L-A-Q-G-I-S-R-V-V-F-D-R-N-G-F-R-Y-H-G-R-I-K-A-L-A-D-G-A-R-E-A-G-L-I-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-K-K-S-G-R-N-I-K-P-G-E-L-N-L-K-E-K-L-V-H-I-N-R-T-A-K-V-V-K-G-G-K-R-F-G-F-N-A-I-V-V-V-G-D-K-E-G-H-V-G-Y-G-L-G-K-A-N-E-V-Q-D-A-I-A-K-G-V-E-D-G-K-K-N-V-I-K-V-P-I-V-K-G-T-I-P-H-P-I-V-A-K-Y-G-S-A-K-V-L-M-K-P-A-T-P-G-T-G-L-I-A-G-G-A-V-R-A-V-L-E-M-A-G-I-H-D-I-L-T-K-S-L-G-S-S-N-P-H-N-V-V-K-A-A-I-K-G-L-Q-N-I-S-D-A-N-D-V-A-E-R-R-S-K-S-L-K-E-V-F-E-S"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-D-L-S-S-L-R-P-A-K-G-A-V-K-A-R-K-R-V-G-R-G-P-G-S-G-N-G-T-T-A-G-K-G-N-K-G-Q-Q-S-R-S-G-Y-Q-R-P-V-I-E-G-G-Q-M-P-I-Y-R-R-L-P-K-F-G-F-T-P-P-N-Q-K-A-V-A-C-V-N-V-A-Q-I-Q-M-W-I-E-K-G-L-V-G-E-E-I-S-V-L-D-L-K-H-L-C-N-A-S-N-Q-E-Y-F-K-V-L-G-N-G-E-L-T-S-T-V-T-I-T-A-H-F-F-S-K-S-A-E-E-K-I-A-K-A-G-G-K-I-V-K-A-Y-R-T-L-E-E-A-A-K-V-N-G-L-P-F-E-E-A-L-L-T-P-K-A-K-V-V-K-V-K-K-E-K-K-S-V-K-S"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-S-I-E-V-E-G-E-I-L-E-A-L-P-N-A-Q-F-R-V-K-L-E-N-G-L-E-V-L-A-H-V-S-G-K-I-R-M-H-Y-I-R-I-L-P-G-D-K-V-K-V-Q-I-S-P-Y-D-L-S-K-G-R-I-T-Y-R-Y-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-R-L-A-G-V-N-L-P-L-N-K-H-A-V-I-A-L-T-Y-V-Y-G-I-G-N-T-S-A-K-N-I-L-A-K-A-G-V-A-P-D-K-K-I-S-E-L-S-D-E-E-A-H-A-I-R-E-I-I-G-N-E-Y-T-V-E-G-E-A-R-A-E-Q-Q-L-S-I-K-R-L-M-D-I-G-C-Y-R-G-L-R-H-R-R-S-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-K-R-K-T-V-A-G-K-K-K-A-G-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-T-A-S-R-K-K-K-K-V-K-V-T-P-E-G-T-V-H-I-K-A-S-F-N-N-V-M-V-T-I-T-D-T-L-G-N-T-V-S-W-S-S-A-G-K-N-G-F-K-G-S-K-K-N-T-P-Y-A-S-Q-V-T-S-E-A-A-A-K-E-A-Y-D-L-G-M-R-Y-V-D-V-L-I-K-G-P-G-S-G-R-D-A-A-I-R-A-L-Q-G-V-G-L-E-V-R-S-I-R-D-I-T-P-L-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-N-I-T-T-A-D-F-F-C-S-Y-S-S-L-N-G-L-P-S-D-G-R-P-E-I-V-F-V-G-R-S-N-V-G-K-S-S-L-L-N-S-L-C-A-R-K-G-L-A-K-T-S-S-T-P-G-K-T-R-L-I-N-Y-F-I-I-N-D-N-L-Y-F-V-D-L-P-G-Y-G-Y-A-K-V-G-Q-G-E-R-E-S-W-G-K-L-L-T-G-Y-I-Q-K-R-G-E-I-A-L-V-V-L-L-V-D-S-R-H-P-G-M-A-S-D-L-E-M-M-E-F-L-D-Y-C-G-R-P-F-G-I-V-L-T-K-W-D-K-L-K-Q-A-E-K-S-K-A-S-R-T-I-E-S-C-A-P-N-A-R-F-I-V-N-Y-S-S-L-S-G-S-G-R-D-R-L-L-A-S-I-D-T-F-T-Q"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-N-T-L-K-Q-Y-E-C-T-V-I-I-D-G-G-L-Q-D-D-A-I-A-A-V-M-E-L-V-K-K-T-V-T-D-K-G-G-V-I-N-N-V-L-E-V-G-R-R-K-M-A-Y-L-I-R-K-T-S-I-G-Y-Y-A-H-I-E-F-D-A-V-P-S-V-I-A-E-I-E-R-V-F-R-Y-E-E-A-I-L-R-F-L-I-I-Q-L-S-S-P-L-L-E-M-R-K-R-V-E-K-Y-S-V-M-L-G-S-P-E-D-Q-A-E-A-E-A-D-A-D-A-K-N"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-N-A-L-A-S-K-K-K-V-S-K-N-Q-V-V-F-F-D-Y-R-D-E-R-K-L-K-R-F-I-N-D-Q-G-K-I-I-P-R-R-I-T-G-L-S-A-K-E-Q-S-L-L-T-H-S-I-K-W-A-R-F-L-A-I-I-P-Y-V-A-D-E-Y-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-I-I-L-R-K-D-V-A-T-L-G-D-A-G-E-V-V-T-V-K-N-G-Y-A-N-N-Y-L-I-P-Q-G-Y-A-I-R-A-T-E-G-T-L-K-A-L-E-T-E-K-K-Q-Q-A-R-K-I-E-L-Q-R-T-N-A-R-E-L-A-A-K-I-E-Q-M-T-L-K-V-L-A-K-A-G-E-S-G-K-L-F-G-T-V-T-A-G-D-I-A-E-A-L-K-A-Q-G-V-D-I-D-R-R-K-I-H-L-E-A-P-I-K-A-L-G-K-Y-E-A-D-A-K-L-F-M-D-I-T-A-K-L-S-I-E-V-E-A-E-G-A-S-E-E"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-K-S-T-N-S-V-A-S-K-A-R-R-K-R-I-L-K-K-A-K-G-Y-W-G-S-R-G-N-V-L-T-V-V-K-H-A-V-D-K-A-E-Q-Y-A-Y-R-D-R-R-V-K-K-R-N-F-R-S-L-W-I-M-R-I-N-A-A-A-R-Q-N-G-V-S-Y-S-R-L-M-D-A-I-H-K-K-N-I-E-I-D-R-K-A-L-A-E-I-A-V-K-D-P-A-A-F-S-L-I-V-K-T-A-L-D"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-A-A-E-I-K-D-K-V-Y-D-I-I-V-S-K-M-G-V-N-K-D-Q-I-K-P-E-S-K-F-A-D-D-L-G-A-D-S-L-D-T-V-E-L-I-M-E-L-E-N-E-F-G-V-Q-I-P-D-E-D-A-E-K-I-G-T-V-Q-Q-A-I-D-Y-I-V-N-K-K-V-S"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-V-M-K-N-V-L-L-V-G-A-G-G-F-A-G-S-V-A-R-Y-L-V-A-L-A-V-P-F-S-G-T-G-F-P-F-A-T-F-A-V-N-L-L-G-S-F-L-I-G-F-I-S-E-L-A-L-S-T-T-L-L-S-P-E-A-R-L-L-L-T-T-G-F-C-G-G-F-T-T-F-S-T-A-M-Y-E-T-G-G-L-M-R-D-G-E-A-L-Y-A-S-L-Y-V-A-G-S-L-A-G-G-L-A-C-L-F-S-G-T-L-L-A-K-L-W-Q"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-Q-V-Q-N-I-E-G-S-L-N-A-S-G-L-K-F-A-L-V-V-S-R-F-N-D-F-I-G-Q-K-L-V-E-G-A-I-D-C-I-V-R-H-G-G-S-A-D-E-I-T-V-I-R-C-P-G-A-F-E-L-P-S-V-T-R-K-A-M-L-S-G-K-Y-D-A-I-V-T-L-G-V-I-I-R-G-S-T-P-H-F-D-V-I-A-A-E-A-T-K-G-I-A-Q-V-G-M-E-A-A-I-P-V-S-F-G-V-L-T-T-E-N-L-E-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-F-D-A-A-L-A-A-I-E-M-A-N-L-Y-K-Q-L"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-E-I-G-V-D-I-V-E-I-A-R-I-R-S-S-Y-D-R-F-G-E-A-F-M-K-K-I-L-T-S-A-E-M-A-Q-C-L-S-K-P-D-P-V-A-S-L-A-G-R-F-A-A-K-E-A-V-S-K-A-L-G-T-G-I-A-K-G-L-T-W-H-S-I-E-V-L-N-D-E-T-G-K-P-C-V-S-V-Y-A-P-S-F-S-G-R-V-S-I-S-I-S-H-D-R-Y-S-A-V-A-M-A-L-F-E-P-R"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-V-T-T-K-D-V-A-Y-I-A-E-L-A-R-L-K-F-T-D-A-E-Q-E-K-M-A-S-E-L-N-M-I-L-H-Y-I-E-K-L-N-G-I-D-T-E-G-V-E-P-L-S-T-I-H-D-Q-I-N-V-L-R-A-D-V-E-H-T-P-L-S-N-D-E-A-L-K-N-A-P-D-S-Q-D-R-F-F-K-V-P-K-V-I-G"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-M-S-I-A-M-S-V-V-E-A-V-V-D-K-A-R-E-E-G-G-G-K-I-T-G-I-D-L-V-V-G-R-L-A-G-V-E-V-E-S-L-K-F-C-F-G-A-A-A-R-G-T-L-A-E-G-A-E-L-V-I-E-E-P-E-G-R-G-R-C-E-A-C-G-A-E-F-P-V-T-S-F-Y-A-K-C-S-A-C-G-Q-F-R-V-K-I-E-S-G-R-E-L-A-V-R-S-F-T-I-E"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-S-K-T-L-S-F-K-T-Y-S-A-K-P-G-E-V-K-R-T-W-H-I-I-D-A-E-N-Q-V-L-G-R-M-A-A-Q-I-A-N-V-L-R-G-K-H-K-P-Q-F-T-P-H-I-D-T-G-D-F-V-V-V-T-N-A-A-K-V-A-L-S-G-K-K-R-D-D-K-T-Y-F-S-H-S-H-Y-P-G-G-V-R-I-D-S-V-K-D-L-L-Q-K-K-P-E-K-V-I-E-H-A-V-W-G-M-L-P-H-N-N-L-G-R-Q-L-F-K-K-L-K-V-Y-A-G-P-E-H-P-H-A-A-Q-M-P-V-E-M-K-I-N-Q"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-D-E-G-K-K-S-S-A-L-D-H-A-L-R-L-L-A-G-R-A-H-G-R-A-E-L-E-S-K-L-K-K-K-G-F-D-S-E-S-I-A-K-A-L-A-R-L-D-E-L-N-L-T-D-D-R-A-F-A-Q-S-C-T-A-S-M-A-R-R-K-P-E-G-R-L-K-T-R-A-R-L-K-Q-K-G-L-P-D-N-I-I-D-E-A-L-N-G-C-D-Q-T-E-L-C-R-S-A-A-E-K-K-L-R-T-L-P-A-S-P-D-Q-K-K-K-K-L-I-T-F-L-K-N-R-G-F-D-W-E-T-I-R-E-T-V-K-L-V-L-G-E-E-S-A-R-S-D-Q-L-D"} +{"text": "### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-S-L-K-I-T-E-E-C-T-F-C-A-A-C-E-P-E-C-P-V-N-A-I-S-A-G-S-D-I-Y-V-I-D-E-S-A-C-T-E-C-E-G-Y-A-D-S-P-A-C-V-A-V-C-P-A-E-C-I-V-K-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-T-Y-R-R-Q-L-R-E-K-I-I-Q-A-L-Y-T-L-E-L-R-D-V-D-T-D-S-A-A-N-W-L-L-T-K-E-I-M-D-D-P-N-A-M-K-F-F-N-H-L-M-Q-S-I-V-R-N-R-E-E-I-D-R-Y-I-A-K-H-T-F-N-W-D-M-S-R-I-A-I-I-D-K-N-I-L-R-M-A-L-A-E-I-L-Y-C-E-D-I-P-P-K-V-S-I-N-E-A-I-E-I-A-K-K-F-S-S-T-D-K-S-S-K-F-V-N-G-I-L-D-A-I-F-N-D-M-K-A-E-G-R-I-K-K-C-G-R-G-L-V-D-H-S-E-Q-K-M-Q-K-T-E-N-N-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-N-I-P-D-N-L-R-Y-T-K-D-H-E-W-I-K-L-L-E-D-G-L-T-A-L-V-G-I-T-D-F-A-Q-S-E-L-G-D-I-V-F-V-E-T-K-P-V-G-T-K-V-A-A-H-G-T-F-G-T-V-E-A-V-K-T-V-A-D-L-F-A-P-A-A-G-E-I-V-E-V-N-A-G-L-D-D-A-A-I-V-N-S-D-P-Y-N-E-G-W-I-V-K-M-K-L-D-N-P-A-D-V-E-A-L-L-S-P-A-D-Y-S-A-L-I-G-E"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-F-G-L-G-G-Q-E-L-V-L-I-L-L-I-V-L-L-L-F-G-A-Q-K-L-P-E-L-A-K-G-L-G-K-G-I-K-E-F-K-K-A-Q-N-E-I-E-E-E-F-N-K-A-T-D-D-S-S-S-K-E-K-K-E-T-K-A"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-T-V-R-D-V-I-Q-K-I-E-P-R-M-K-K-T-I-E-A-F-Q-H-E-L-A-S-I-R-T-G-K-A-T-T-A-L-L-D-R-V-K-V-E-A-Y-G-S-Q-M-P-L-K-Q-V-G-N-V-G-V-L-D-A-H-T-L-T-V-Q-V-W-D-K-S-M-V-G-A-T-E-R-A-I-R-D-A-G-L-G-L-N-P-S-A-D-G-Q-N-I-R-I-S-I-P-P-L-T-E-E-R-R-K-E-F-V-K-L-T-K-K-F-G-E-D-S-K-V-S-L-R-N-H-R-R-D-L-I-H-E-V-E-K-L-E-K-E-K-L-I-S-E-D-E-L-K-R-G-K-K-D-A-D-D-L-L-H-K-Y-E-K-Q-I-T-E-L-I-A-Q-K-E-K-E-I-M-E-V"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-P-E-I-H-P-K-Y-T-K-V-T-V-N-C-A-N-C-G-T-T-F-E-T-R-S-T-R-N-N-N-I-K-V-D-I-C-S-K-C-H-P-F-Y-T-G-K-Q-V-L-V-D-T-A-G-R-V-D-R-F-N-K-R-F-A-K-A-A-P-K-A-S-A-Q"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Q-A-L-I-E-I-S-D-K-Q-Y-L-V-K-A-G-D-K-I-F-V-P-K-Q-K-A-A-A-G-D-V-I-E-V-K-T-L-M-Q-V-N-Q-A-D-S-A-L-K-A-G-T-A-T-I-K-V-L-E-H-V-R-D-E-T-I-I-V-F-R-K-K-R-R-K-R-F-Q-K-R-N-G-H-R-Q-H-M-T-Q-V-E-V-L-S-L"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-R-K-H-H-K-E-Q-E-E-I-Q-E-Q-E-T-I-S-A-G-A-A-E-T-P-A-E-E-T-A-A-I-P-A-A-T-E-A-D-M-D-A-E-I-S-A-R-D-A-E-I-Q-K-L-R-E-E-V-M-R-R-A-A-E-F-E-N-F-R-K-Q-K-E-R-E-A-A-L-S-G-T-R-M-L-E-N-I-V-R-E-L-L-P-L-I-D-D-L-K-R-L-M-S-H-I-P-A-E-M-Q-A-M-A-E-A-K-P-F-I-E-G-V-E-L-I-H-K-N-F-M-S-L-L-E-R-K-G-V-K-E-I-E-A-K-G-K-M-L-D-V-N-F-H-E-A-I-T-Q-I-D-A-P-G-A-E-P-D-T-I-V-E-E-Y-Q-T-G-Y-T-L-G-D-R-V-I-R-H-A-K-V-I-V-A-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-L-P-I-N-T-Y-S-D-P-V-L-A-M-K-A-K-P-L-K-G-V-D-S-A-I-E-E-L-I-A-E-M-F-D-T-M-Y-K-A-P-G-I-G-L-A-A-P-Q-V-G-H-S-L-R-L-V-V-V-D-I-S-T-I-K-E-Y-A-D-F-K-P-M-V-V-I-N-P-R-I-V-A-V-R-G-R-S-L-M-E-E-G-C-L-S-V-P-G-I-A-G-N-V-V-R-P-S-A-I-T-L-H-Y-R-D-E-K-F-E-E-H-T-A-D-F-H-S-M-M-A-R-V-L-Q-H-E-I-D-H-L-D-G-T-L-F-V-D-R-M-D-K-R-D-R-R-K-I-Q-K-E-L-D-A-I-A-E-G-R-V-K-A-D-Y-P-L-A-R-D-V-N-R-V-E-A-E-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-D-R-I-Y-L-T-R-D-G-Y-N-R-L-K-E-E-L-H-L-L-M-T-E-T-R-K-E-V-L-E-K-I-A-E-A-R-S-H-G-D-L-S-E-N-A-E-Y-D-A-A-R-E-E-Q-S-Q-L-E-A-K-I-G-E-I-E-N-K-L-A-S-A-T-I-L-D-P-K-Q-I-K-T-D-R-V-Y-I-L-T-S-V-K-L-R-N-L-D-A-E-D-E-I-I-E-Y-T-L-V-S-S-E-E-A-D-S-D-L-G-K-I-S-V-R-S-P-V-G-R-S-L-I-G-K-S-V-G-D-K-V-T-I-S-V-P-K-G-E-L-H-Y-E-I-L-D-I-F-V-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-P-L-Q-I-F-N-T-T-K-R-T-I-D-E-T-L-L-A-E-V-I-R-L-V-I-G-E-E-G-G-A-V-G-S-I-E-A-I-Y-C-G-N-K-M-I-R-R-I-N-R-D-F-L-G-H-D-Y-V-T-D-T-I-T-F-G-Y-N-E-G-G-E-V-D-G-E-F-Y-I-S-L-D-V-I-E-S-N-A-R-R-F-G-V-S-F-E-D-E-L-L-R-V-T-I-H-S-A-L-H-L-M-G-Y-D-D-E-T-S-E-L-R-A-A-M-S-L-R-E-D-H-Y-L-Y-R-L-R-H"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-E-T-R-A-L-S-V-N-L-R-E-V-K-K-N-G-A-A-K-L-R-R-L-G-Q-V-P-A-V-V-Y-H-K-G-E-A-T-V-A-I-S-V-E-E-I-S-L-N-K-L-V-H-S-S-E-S-H-M-I-D-L-Q-Y-P-D-G-K-S-V-R-S-F-I-K-D-V-Q-F-D-P-V-T-D-R-V-I-H-A-D-F-Q-L-F-S-T-D-E-V-V-E-M-E-V-P-I-H-L-E-G-E-C-P-G-V-K-I-G-G-G-K-I-Q-I-N-V-H-T-L-P-L-K-G-K-P-E-A-M-P-E-H-F-T-I-D-V-S-A-L-E-L-G-Q-T-L-H-I-R-D-L-Q-A-I-A-P-E-G-V-Q-I-L-G-D-A-D-T-S-V-V-S-V-V-A-P-R-K-E-A-E-T-A-A-E-G-A-T-A-E-A"} +{"text": "### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-A-L-Y-I-T-E-E-C-T-Y-C-G-A-C-E-P-E-C-P-T-N-A-I-S-A-G-S-E-I-Y-V-I-D-A-A-S-C-N-E-C-A-G-F-A-D-S-P-A-C-V-A-V-C-P-A-E-C-I-V-Q-G"} +{"text": "### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-A-H-R-I-T-D-E-C-T-Y-C-A-A-C-E-P-E-C-P-V-S-A-I-S-A-G-D-S-I-Y-V-I-D-E-N-V-C-V-D-C-I-G-Y-H-D-E-P-A-C-V-A-V-C-P-V-D-C-I-I-K-V"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-V-G-L-G-N-P-E-L-R-H-A-A-T-R-H-N-I-G-F-D-V-I-D-H-L-A-G-S-S-T-F-S-S-G-K-G-N-Y-R-F-T-K-I-T-A-P-G-G-P-L-I-L-V-K-P-M-T-Y-M-N-L-S-G-H-A-V-V-A-A-M-N-F-W-K-I-E-R-E-N-L-L-V-I-C-D-D-V-N-I-P-L-G-T-I-R-I-R-A-K-G-S-A-G-G-Q-N-G-L-K-H-I-I-Q-S-L-G-S-E-E-F-A-R-L-R-V-G-V-G-G-E-N-M-P-A-S-L-S-S-F-V-L-S-K-F-T-A-E-E-R-K-C-I-D-K-V-I-P-V-C-A-D-A-V-L-D-F-A-S-L-G-V-E-H-A-M-T-K-Y-N-G-Q-V-C"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-R-E-F-A-L-K-G-N-V-V-D-M-A-V-G-I-I-I-G-G-A-F-G-A-L-V-N-S-L-V-N-D-L-L-M-P-P-L-G-L-L-L-K-G-V-D-F-S-N-L-F-V-V-L-K-E-G-T-P-P-G-P-Y-I-A-L-A-D-A-K-T-A-G-A-V-T-L-N-Y-G-L-F-V-N-A-L-I-G-F-L-I-M-A-F-A-V-F-L-L-V-R-S-I-N-R-L-R-S-L-S-E-K-S-A-A-P-A-V-A-P-Q-T-K-E-C-P-F-C-F-S-I-I-P-L-K-A-V-R-C-P-N-C-T-S-Q-L"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-L-F-L-T-G-V-V-L-K-P-K-G-L-K-G-E-L-K-V-K-P-V-T-D-F-P-E-S-F-L-T-R-R-E-Y-Y-I-G-K-T-P-E-D-A-V-L-R-K-V-Q-S-A-R-F-H-Q-G-F-A-W-L-V-F-E-G-A-G-S-R-E-G-A-E-A-L-V-G-C-G-L-Y-V-T-R-D-A-L-V-A-M-P-D-D-R-A-Y-I-H-E-L-I-G-L-D-V-F-D-E-T-E-G-R-V-G-K-I-S-D-V-L-Q-M-P-A-H-D-V-Y-E-V-D-T-G-D-R-K-V-L-I-P-A-V-E-D-F-I-T-E-T-D-L-E-K-G-M-V-R-L-K-R-F-K-E-F-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-D-Q-L-I-Q-L-V-E-A-T-Q-Q-R-N-D-I-P-E-V-R-P-G-D-T-V-R-I-Q-L-K-V-I-E-G-E-K-E-R-L-Q-A-F-E-G-V-V-I-G-D-K-G-M-G-A-S-K-T-I-T-V-R-K-I-S-H-G-V-G-V-E-R-I-I-P-V-N-S-P-N-I-E-S-V-T-V-V-R-S-G-K-A-R-R-A-K-L-F-Y-L-R-K-R-T-G-K-A-A-L-K-V-K-E-R-K-S-A-S-A-E-A"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-L-V-L-V-T-Y-D-V-N-T-E-T-P-A-G-R-R-R-L-R-R-I-A-K-T-C-Q-N-Y-G-Q-R-V-Q-F-S-V-F-E-C-N-V-D-P-A-Q-W-V-K-L-R-S-K-L-L-N-E-M-D-P-K-L-D-S-L-R-F-Y-F-L-G-S-N-W-Q-G-R-V-E-H-E-G-A-K-E-P-R-D-L-E-G-T-L-I-L"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-A-S-R-Q-K-K-I-R-E-L-I-E-N-H-E-V-S-G-Q-Q-E-L-L-G-M-L-E-K-E-G-I-V-V-A-Q-A-T-L-S-R-D-F-A-E-M-G-V-V-R-N-R-T-S-D-G-G-Y-R-L-A-V-P-E-E-P-Q-V-D-I-I-K-G-L-V-G-M-E-V-L-S-V-A-S-N-E-T-S-I-I-I-R-T-L-P-G-R-A-H-G-V-G-S-F-L-D-R-L-T-N-D-N-I-L-G-T-I-A-G-D-D-T-V-L-V-I-P-S-T-V-R-K-I-S-S-V-K-S-Y-I-Q-K-I-L-S-Q-P"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-S-G-K-Y-F-E-A-T-D-Q-N-F-Q-A-E-I-L-N-S-D-K-V-A-L-V-D-F-W-A-A-W-C-G-P-C-M-M-L-G-P-V-I-E-E-L-A-G-D-Y-E-G-K-A-I-I-A-K-L-N-V-D-E-N-P-N-T-A-G-Q-Y-G-I-R-S-I-P-T-M-L-I-I-K-G-G-K-V-V-D-Q-M-V-G-A-L-P-K-N-M-I-A-K-K-L-D-E-H-I-G"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-M-P-N-F-G-D-M-M-K-Q-L-Q-E-A-G-A-K-M-Q-D-L-Q-K-Q-L-E-K-L-V-S-E-G-E-A-G-G-G-M-V-R-A-K-V-N-G-R-Q-K-L-L-E-L-T-I-D-P-E-I-M-D-D-V-D-M-V-Q-D-L-V-V-A-A-V-N-K-A-L-E-A-S-A-Q-L-A-Q-S-E-I-Q-K-A-A-G-G-M-I-N-P-A-D-L-M-K-Q-F-G-G-Q-G"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-A-Q-T-L-D-D-L-I-R-T-S-E-L-P-V-F-I-D-F-W-A-D-W-C-G-P-C-K-M-V-A-P-S-V-K-Q-L-A-S-E-F-K-G-R-L-I-V-V-K-V-N-V-D-Q-Q-P-D-A-A-A-R-F-Q-V-Q-G-I-P-A-L-M-L-F-V-G-G-Q-L-K-W-R-T-A-G-A-I-P-Y-Q-Q-M-R-Q-E-V-L-K-A-I-G"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-K-K-Q-G-K-P-E-Y-V-T-A-I-S-N-R-K-A-R-F-E-Y-E-I-L-D-T-I-E-A-G-I-E-L-L-G-S-E-V-K-S-V-R-L-G-K-A-S-L-S-E-S-Y-A-M-I-H-H-G-Q-V-W-L-E-N-M-Q-I-T-P-Y-E-H-N-T-L-D-T-L-E-P-K-R-S-R-R-L-L-L-H-K-A-E-I-M-R-L-Q-S-K-I-S-E-K-G-L-T-L-I-P-L-K-A-Y-F-N-K-R-G-V-L-K-I-E-L-G-L-A-R-G-K-K-L-Y-D-K-R-E-T-I-K-N-R-D-A-K-R-Q-L-Q-Q-L-R-K-Q-Y"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-L-K-P-L-A-D-R-V-I-V-K-P-A-P-A-E-E-K-T-K-G-G-L-Y-I-P-D-T-G-K-E-K-P-M-Y-G-E-V-V-A-V-G-P-G-K-V-S-D-A-G-Q-V-V-A-M-Q-V-K-A-G-D-K-V-L-Y-G-K-Y-S-G-T-E-V-H-V-E-G-E-D-Y-L-I-M-R-E-S-D-I-F-A-I-L-G"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-S-D-L-Y-R-F-G-I-S-L-E-R-K-L-I-E-S-F-D-R-H-I-K-A-Q-G-Y-Q-S-R-S-E-A-L-R-D-L-I-R-E-E-L-L-R-K-T-T-A-E-G-G-L-V-A-G-A-I-V-M-T-Y-D-H-H-K-R-D-L-V-N-R-L-I-D-I-Q-H-D-F-H-D-L-I-I-S-T-Q-H-V-H-L-D-H-E-N-C-L-E-V-I-A-V-K-G-N-A-P-E-I-E-K-L-S-S-A-L-K-V-L-V-G-V-K-H-L-D-L-S-L-S-S-A-D"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-P-I-K-S-R-I-R-T-V-P-D-Y-P-K-K-G-I-M-F-R-D-I-T-T-L-I-K-D-P-V-G-F-R-L-V-I-D-N-M-T-Q-H-Y-L-S-N-G-V-D-F-D-A-I-V-G-I-E-S-R-G-F-I-L-G-G-A-L-A-Y-T-L-G-K-G-F-V-P-V-R-K-P-G-K-L-P-A-D-V-V-Q-L-E-Y-E-L-E-Y-G-T-D-K-I-E-M-H-T-D-A-L-V-Q-G-Q-R-V-L-L-V-D-D-L-L-A-T-G-G-T-A-L-A-A-A-G-L-V-E-K-L-G-G-V-V-A-S-M-A-F-I-V-N-L-P-D-I-G-G-E-K-K-I-R-E-K-G-Y-N-I-Y-F-L-T-E-F-E-G-D"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-L-H-K-S-A-E-K-R-L-R-Q-A-A-R-R-N-E-R-N-R-A-R-K-K-E-L-K-G-V-L-K-N-M-Q-K-L-I-D-A-N-A-A-K-S-E-V-E-A-A-Y-K-A-A-V-Q-K-L-D-R-L-G-V-K-R-Y-I-H-P-N-K-A-S-R-K-K-A-Q-L-T-K-A-L-N-N-Y-T-P-T-A-S"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-S-A-E-Q-V-L-D-Q-G-R-L-I-V-F-S-A-P-S-G-T-G-K-S-T-V-A-K-L-V-M-E-R-L-G-S-L-E-F-S-V-S-A-T-T-R-Q-M-R-A-G-E-R-D-G-V-D-Y-H-F-L-S-R-E-E-F-E-K-K-I-A-E-N-G-F-I-E-H-E-F-F-F-G-N-F-Y-G-T-L-L-D-K-T-I-D-A-I-K-A-G-H-N-L-L-F-D-L-D-V-K-G-A-L-N-L-K-R-I-F-G-D-Q-A-L-L-V-F-L-K-P-P-S-M-E-E-L-A-R-R-L-Q-A-R-D-S-E-S-A-E-A-L-K-S-R-L-E-R-A-E-M-E-L-S-H-A-G-E-F-D-F-V-V-V-N-D-D-L-G-R-T-V-D-A-V-A-T-R-I-A-E-F-L-P-Q-P"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-G-L-T-K-E-H-K-T-E-I-I-T-K-F-G-D-S-A-T-D-T-G-K-A-E-V-Q-V-A-L-F-T-R-R-I-T-D-L-T-G-H-L-Q-Q-H-P-K-D-K-H-S-R-R-G-L-L-M-L-V-G-K-R-K-R-V-L-N-Y-L-K-K-V-D-I-E-R-Y-R-K-V-L-A-D-L-D-L-R-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-I-R-T-D-K-V-S-S-L-L-Q-R-E-L-S-A-I-F-E-K-E-L-P-R-S-G-P-L-V-T-V-T-E-V-R-M-T-A-D-L-G-I-A-R-V-Y-V-S-V-I-G-S-E-A-Q-R-A-E-V-M-E-Y-L-D-A-E-N-K-M-I-R-K-T-L-S-A-K-I-R-H-Q-F-R-R-I-P-E-L-E-F-Y-E-D-R-L-F-E-Q-A-N-R-I-E-Q-L-L-K-S-V-K-P-A-R-D-E-E-Q-H"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-D-D-L-I-K-K-A-I-G-E-T-I-G-E-L-S-A-T-S-G-E-E-I-Y-V-V-E-A-A-I-R-A-G-G-R-K-I-E-L-T-V-D-T-D-K-G-V-S-I-D-Q-C-A-K-L-S-R-A-I-R-A-R-L-E-A-C-E-E-D-S-M-L-S-S-G-E-F-D-L-M-V-S-S-P-G-I-G-E-P-I-Q-V-Q-R-Q-Y-L-R-H-L-G-R-L-I-R-V-N-Y-L-D-E-E-E-Q-P-K-E-I-T-G-K-L-L-E-A-A-V-G-P-E-A-E-Q-P-S-I-T-I-E-A-V-K-E-G-R-K-K-R-T-A-G-E-P-P-V-T-I-R-L-A-D-V-V-R-A-V-V-Q-T-E-L"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-S-I-S-N-V-S-R-G-A-I-I-R-W-N-G-A-P-H-S-I-E-S-L-V-H-R-T-P-G-N-L-R-A-F-Y-Q-A-S-M-K-N-L-K-T-G-R-N-V-E-Y-R-F-S-A-T-E-Q-V-D-V-I-V-T-E-R-K-K-Y-Q-Y-L-Y-R-D-G-E-D-Y-V-M-M-D-T-E-T-F-D-Q-I-N-V-P-E-V-A-I-G-P-A-S-R-F-L-K-D-S-V-M-V-D-I-V-F-A-D-D-G-S-I-L-E-V-E-L-P-T-F-V-E-L-E-V-T-E-T-S-P-A-S-K-D-D-R-A-T-S-G-T-K-P-A-I-V-E-T-G-A-E-V-N-V-P-M-F-I-Q-T-G-S-I-I-R-I-D-T-R-S-G-E-Y-M-E-R-V-K-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-S-I-E-T-L-V-E-E-I-G-K-L-T-L-T-E-A-S-E-L-V-K-A-L-E-E-K-F-G-V-S-A-A-P-A-V-M-A-G-A-V-M-A-A-P-A-G-E-A-A-A-A-E-E-K-T-E-F-D-V-V-L-K-S-A-G-A-N-K-I-N-V-I-K-V-V-R-A-I-T-G-L-G-L-K-E-A-K-D-M-V-D-G-A-P-K-T-V-K-E-A-V-S-K-D-E-A-E-K-I-A-K-E-L-K-D-A-G-A-E-V-E-L-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-M-K-R-D-T-K-E-Q-I-A-Q-E-I-A-E-K-F-Q-K-S-Q-G-F-Y-F-T-E-F-Q-G-L-D-V-Q-K-M-S-Q-L-R-L-E-F-R-K-A-G-I-E-Y-R-V-V-K-N-T-L-I-K-K-A-L-K-D-A-A-D-V-D-K-L-A-A-G-L-K-N-T-T-A-V-A-F-A-Y-D-D-P-I-A-P-A-K-I-I-K-K-F-S-K-D-N-E-A-L-K-F-K-M-A-S-I-D-G-Q-V-F-G-S-D-S-L-P-Q-L-S-E-M-L-S-K-T-E-N-I-G-R-L-A-G-L-L-N-N-M-V-A-S-V-P-M-V-M-N-A-V-M-R-N-L-V-S-V-I-D-Q-V-G-K-L-E-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-T-G-F-I-K-L-Q-I-P-A-G-G-A-N-P-A-P-P-V-G-P-A-L-G-Q-K-G-V-N-I-M-E-F-C-K-Q-F-N-A-K-T-Q-S-E-A-G-M-I-I-P-V-V-I-T-V-Y-S-D-K-S-F-T-F-V-T-K-T-P-P-A-A-V-L-L-L-K-E-A-K-L-Q-K-G-S-G-E-P-N-R-N-K-V-G-T-V-T-M-D-Q-V-R-K-I-A-E-L-K-R-P-D-L-N-S-I-D-L-E-G-A-T-Q-M-V-I-G-T-A-R-S-M-G-I-V-V-E-G"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-S-S-S-H-K-R-I-I-G-I-D-F-G-T-K-R-I-G-V-A-L-S-D-P-L-R-M-F-A-Q-P-L-G-T-F-D-M-E-G-L-V-R-V-L-S-R-V-R-D-D-E-G-I-E-L-V-V-V-G-Y-P-M-S-D-K-G-E-E-N-R-M-T-G-V-I-D-R-F-V-A-E-L-R-E-S-F-P-G-T-L-I-E-T-F-D-E-H-R-S-S-R-T-A-M-K-I-L-A-A-S-G-S-S-R-K-K-R-N-E-K-G-R-L-D-T-A-A-A-C-L-I-L-Q-G-Y-L-D-S-H-S"} +{"text": "### FUNCTION This basic c-type monoheme cytochrome has been found exclusively in the green photosynthetic bacteria, although its role in bacterial photosynthesis is not established It has an unusually low redox potential compared with mitochondrial cytochrome c It is reactive with cytochrome c oxidases but not with reductases ### SEQUENCE -M-S-R-F-V-S-A-A-L-V-G-A-A-L-L-V-S-G-N-A-F-A-Y-D-A-A-A-G-K-A-T-Y-D-A-S-C-A-T-C-H-K-T-G-M-M-G-A-P-K-V-G-D-K-A-A-W-A-P-R-I-A-Q-G-M-N-T-L-V-S-K-S-I-K-G-Y-K-G-T-K-G-M-M-P-A-K-G-G-N-A-K-L-T-D-A-Q-V-G-N-A-V-A-Y-M-V-G-Q-S-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-L-T-S-G-I-I-L-L-E-G-G-L-L-N-P-N-P-G-L-I-F-W-T-A-L-T-F-L-I-V-L-V-I-L-R-K-T-A-W-G-P-I-L-S-M-L-E-E-R-A-K-S-I-Q-S-A-I-D-R-A-H-T-A-K-D-E-A-E-A-I-L-K-K-N-R-D-L-L-A-K-A-D-A-E-A-D-K-I-I-R-E-A-K-E-V-A-D-K-L-R-A-D-L-T-E-K-A-H-D-E-S-R-K-I-I-A-S-A-K-E-E-I-E-Q-E-K-R-R-A-L-D-V-L-R-N-E-V-A-D-M-A-V-K-G-A-E-K-I-I-R-T-T-L-D-A-D-K-Q-K-A-V-V-N-D-M-I-K-E-M-A-A-S-R-N"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-S-A-I-A-S-R-R-Y-A-V-A-L-L-E-V-A-V-E-G-N-F-L-E-K-V-T-E-D-L-Q-K-I-Q-E-V-L-S-G-S-H-E-L-V-L-A-L-K-S-P-L-I-N-V-D-L-K-S-K-I-L-E-E-I-F-R-N-K-V-D-E-K-T-M-V-F-I-K-L-L-A-H-K-K-R-A-A-L-L-A-G-V-I-S-E-F-N-A-L-I-D-E-R-N-G-V-I-N-A-D-V-K-S-A-I-K-L-S-D-E-Q-A-K-E-L-V-N-S-L-S-V-R-T-G-K-K-I-R-A-K-M-R-L-D-E-N-L-I-G-G-V-T-V-K-I-G-D-T-I-I-D-G-S-I-S-H-Q-L-E-M-L-R-H-S-L-V-A-Q-P-A"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-R-T-A-V-F-G-G-S-F-D-P-P-H-N-G-H-L-A-L-S-L-F-A-R-E-L-A-G-L-D-R-L-I-V-S-V-S-K-N-P-F-K-A-A-A-D-A-S-D-D-D-R-S-A-M-A-R-L-L-V-A-E-I-N-V-A-G-V-F-A-E-I-S-G-W-E-L-Q-Q-S-G-P-S-Y-T-I-D-L-L-R-H-V-E-E-R-C-P-G-D-E-L-V-L-L-V-G-E-D-S-Y-L-Q-M-P-Q-W-K-F-A-S-E-I-L-K-H-C-T-I-A-V-F-G-R-S-D-I-D-A-A-D-A-P-P-S-D-P-L-L-P-A-I-H-Y-D-F-D-M-P-V-S-A-T-K-I-R-R-L-A-A-A-G-Q-P-I-G-Q-F-V-P-S-S-I-A-Q-Y-I-A-E-H-K-L-Y-S-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-Y-P-G-M-L-S-E-K-R-T-N-A-L-P-R-G-E-I-A-R-G-K-S-A-V-S-R-L-F-S-Q-G-G-R-L-K-G-G-F-L-L-L-I-Y-S-A-S-R-P-V-E-Q-A-P-R-I-P-V-R-V-L-F-T-V-G-K-K-L-V-P-R-A-V-D-R-N-R-I-K-R-L-M-R-E-A-Y-R-L-E-K-N-I-L-T-R-A-L-A-F-D-A-G-K-G-D-H-Q-V-M-L-A-F-L-Y-R-A-R-A-D-A-I-P-S-L-E-R-F-R-A-E-I-R-H-M-L-K-N-L-L-S-N-R-L-P-Q-T-R-E-G-D-R-I-E"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-F-K-E-Y-K-I-Y-K-F-F-E-Q-V-K-Q-E-T-Y-K-V-V-W-P-T-R-K-E-L-V-A-S-T-L-V-V-V-V-A-V-F-I-F-S-L-I-C-L-V-L-D-Y-S-I-H-N-I-M-Q-L-L-L-N-I-G-K"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-I-E-E-K-E-Q-T-V-G-G-F-V-L-A-G-S-A-Q-E-K-T-K-T-A-Q-V-V-A-T-G-Q-G-V-R-T-L-N-G-D-L-V-A-P-S-V-K-P-G-D-R-V-L-V-E-A-H-A-G-I-D-V-K-D-G-D-E-K-Y-I-I-V-G-E-A-N-I-L-A-I-I-E-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-L-K-P-L-G-D-R-I-V-V-H-F-E-E-T-E-E-K-T-A-S-G-F-V-L-A-G-A-S-H-E-A-T-K-T-A-E-V-L-A-V-G-E-G-I-R-T-L-T-G-E-L-I-A-L-S-V-A-A-G-D-K-V-L-V-E-N-G-A-G-V-N-V-K-D-G-D-D-S-V-S-I-I-R-E-A-D-I-L-A-V-L-A"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-E-V-E-E-K-E-Q-K-V-G-G-F-V-I-A-G-A-G-Q-D-A-T-K-T-A-K-V-V-A-V-G-E-G-I-R-T-L-N-G-E-L-V-A-P-S-V-K-A-G-D-T-V-L-V-E-S-H-V-G-T-E-V-K-D-G-E-E-K-Y-L-V-V-N-E-V-N-I-L-A-I-V-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-V-E-E-E-K-E-Q-T-V-G-G-F-V-L-A-G-A-S-K-E-R-T-Q-V-A-T-V-V-A-V-G-D-G-A-R-T-L-T-G-E-L-V-A-P-S-V-A-A-G-D-K-V-I-I-E-N-G-V-G-I-E-V-K-D-D-D-N-T-V-T-I-V-R-E-A-D-I-L-A-I-L-A"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-V-E-E-K-E-Q-K-V-G-G-F-V-I-A-G-N-G-Q-A-A-T-K-T-A-E-V-V-A-V-G-Q-G-I-R-T-L-N-G-E-L-V-S-L-S-V-K-E-G-E-K-V-L-V-E-N-H-A-G-V-E-V-K-D-G-D-E-A-Y-L-L-V-S-E-A-N-I-L-A-V-V-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-V-E-E-R-E-Q-K-V-G-G-F-V-I-A-G-A-G-Q-D-A-T-K-T-A-K-V-I-A-V-G-E-G-I-R-T-L-N-G-E-L-V-A-P-S-V-K-A-D-D-T-V-L-V-E-S-H-A-G-I-E-V-K-D-G-E-E-K-Y-L-V-V-N-E-T-N-I-L-A-I-V-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-V-E-E-K-E-Q-K-V-G-G-F-V-I-A-G-A-G-Q-D-A-T-K-T-A-K-V-V-A-A-G-D-G-I-R-T-L-N-G-E-L-V-A-P-S-V-K-A-G-D-T-V-L-V-E-S-H-A-G-I-E-V-K-D-G-E-E-K-Y-L-V-V-N-E-A-N-I-L-A-I-V-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-R-I-K-P-L-G-D-R-V-V-I-K-R-L-E-A-E-E-K-T-K-S-G-I-V-L-P-G-S-A-K-E-K-P-Q-E-A-E-I-V-A-V-G-P-G-G-L-V-D-G-K-E-V-N-M-E-V-K-V-G-D-R-V-L-F-S-Q-Y-A-G-N-E-V-K-I-D-G-E-E-Y-I-I-L-R-Q-N-D-I-L-A-I-V-E"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-I-V-A-V-P-N-S-G-A-S-R-I-N-Q-S-G-V-E-A-L-R-E-F-P-N-F-P-I-G-G-I-L-F-K-D-I-A-P-M-L-A-G-R-G-A-L-G-E-V-V-S-T-V-A-S-Q-V-S-G-T-E-I-D-A-I-L-A-V-D-A-R-G-F-I-L-G-A-S-L-A-D-R-L-G-C-G-F-I-M-V-R-K-P-G-K-L-P-G-D-V-L-S-F-E-Y-S-C-E-Y-C-S-G-T-L-E-V-T-A-G-L-I-G-D-G-L-R-C-L-I-A-D-D-L-L-A-T-G-G-T-A-R-A-T-G-N-F-V-K-S-Q-G-G-E-I-A-G-Y-A-F-I-L-E-I-E-V-L-K-G-R-R-Q-L-D-D-A-P-V-I-S-A-M-T-C"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-C-R-C-S-A-D-S-S-P-V-D-V-K-D-I-L-N-R-L-K-S-L-S-A-A-E-E-F-F-E-A-L-G-V-P-Y-D-P-K-V-L-D-V-S-R-L-H-I-M-K-R-M-G-Q-Y-L-A-A-E-D-F-S-H-L-P-D-R-V-I-A-A-R-A-R-A-I-L-E-R-A-Y-C-D-F-A-T-S-A-P-L-S-H-R-V-F-K-V-L-K-D-H-N-P-N-R-P-V-T-P-G-R-T-V-V-P-L-D-S-F-L-K-P-F-E-K-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-K-D-T-I-R-T-E-G-V-V-T-E-A-L-P-N-A-T-F-R-V-K-L-D-S-G-P-E-I-L-A-Y-I-S-G-K-M-R-M-H-Y-I-R-I-L-P-G-D-R-V-V-V-E-I-T-P-Y-D-P-T-R-G-R-I-V-Y-R-K"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-E-L-A-N-I-P-E-L-L-A-S-R-I-R-D-V-A-D-Y-P-E-P-G-V-M-F-K-D-I-T-P-L-L-A-D-P-V-A-F-T-A-L-T-D-T-L-A-A-G-R-R-R-H-P-R-T-K-V-V-G-L-E-A-R-G-F-I-L-G-A-P-V-A-V-R-A-G-L-G-F-I-P-V-R-K-A-G-K-L-P-G-A-T-L-S-Q-A-Y-D-L-E-Y-G-S-A-E-I-E-V-H-A-E-D-L-A-A-G-D-R-V-L-I-V-D-D-V-L-A-T-G-G-T-A-E-A-A-I-Q-L-I-R-R-A-G-A-E-V-C-G-L-A-V-L-M-E-L-G-F-L-G-G-R-A-R-L-E-P-I-L-D-G-A-P-L-E-A-L-L-Q-V"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-T-V-D-H-T-R-M-N-A-P-A-V-R-V-A-K-T-M-K-T-P-H-G-D-T-I-T-V-F-D-L-R-F-C-I-P-N-K-Q-V-M-P-E-K-G-I-H-T-L-E-H-L-F-A-G-F-M-R-N-H-L-N-G-E-G-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-E-P-A-E-V-R-V-A-D-A-W-K-A-A-M-A-D-V-L-K-V-K-D-Q-S-Q-I-P-E-L-N-I-Y-Q-C-G-T-Y-H-M-H-S-L-T-E-A-Q-D-I-A-H-H-I-L-D-S-D-V-L-V-N-K-N-D-E-L-A-L-P-E-E-K-L-T-E-L-K-V"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-I-R-P-L-H-D-R-I-V-V-R-R-K-E-E-E-T-A-T-A-G-G-I-I-L-P-G-A-A-A-E-K-P-N-Q-G-V-V-I-S-V-G-T-G-R-I-L-D-N-G-S-V-Q-A-L-A-V-N-E-G-D-V-V-V-F-G-K-Y-S-G-Q-N-T-I-D-I-D-G-E-E-L-L-I-L-N-E-S-D-I-Y-G-V-L-E-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-K-K-K-A-E-D-K-Q-P-I-I-K-D-E-A-V-E-E-P-K-S-D-S-K-V-N-A-L-S-A-K-I-A-E-L-Q-Q-Q-L-D-D-S-Q-N-D-Y-L-R-A-Q-A-E-I-Q-N-M-Q-K-R-S-Q-K-E-Q-S-A-L-A-K-Y-G-A-Q-R-L-A-K-E-V-V-P-V-M-D-D-L-K-R-A-L-Q-V-Q-V-D-N-D-S-G-Q-Q-L-K-T-G-I-E-M-V-Y-K-H-L-E-K-A-L-N-D-N-D-I-K-E-I-D-A-D-G-V-A-F-D-P-E-L-H-Q-A-V-Q-T-V-P-A-D-D-D-H-P-A-D-T-V-V-Q-V-L-Q-S-G-Y-K-L-A-D-R-V-L-R-P-A-M-V-V-V-A-Q"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-G-G-G-R-I-P-L-W-I-V-A-T-V-A-G-T-G-V-L-V-V-V-G-L-F-F-Y-G-A-Y-A-G-L-G-S-S-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-P-T-R-S-T-N-P-N-K-Q-P-V-E-L-N-R-T-S-L-F-L-G-L-L-L-V-F-V-L-G-I-L-F-S-S-Y-F-F-N"} +{"text": "### FUNCTION Component of the type IV secretion system VirB/VirD4 which could be a major virulence determinant for subversion of human endothelial cell function VirB2 seems to constitute the major pilus component ### SEQUENCE -M-T-E-T-I-S-R-N-I-I-F-I-V-I-V-L-L-L-T-A-L-V-V-S-N-P-S-Y-A-A-N-S-A-S-S-L-G-N-V-D-S-V-L-Q-N-I-V-T-M-M-T-G-T-T-A-K-L-I-A-I-I-C-V-A-A-V-G-I-G-W-M-S-G-F-I-D-L-R-K-A-A-Y-C-I-L-G-I-G-I-V-F-G-A-P-T-L-V-S-T-L-M-G-S-S"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-S-K-E-V-I-V-E-S-F-E-L-D-H-T-I-V-K-A-P-Y-V-R-L-I-G-E-E-S-G-P-K-G-D-V-I-S-N-F-D-I-R-L-V-Q-P-N-E-D-S-I-P-T-A-G-L-H-T-I-E-H-L-L-A-M-L-I-R-K-R-I-D-G-M-I-D-C-S-P-F-G-C-R-T-G-F-H-M-I-M-W-G-R-H-T-P-S-E-I-A-Q-V-I-K-S-C-L-E-E-I-A-E-T-T-T-W-E-D-V-P-G-T-T-I-E-S-C-G-N-Y-K-D-H-S-L-F-S-A-K-E-W-A-K-L-I-L-K-Q-G-I-S-D-N-A-F-E-R-H-V-I"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-S-Q-L-V-R-K-G-R-E-K-L-V-V-K-G-K-S-P-A-L-K-E-S-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-N-G-I-E-V-T-S-Y-I-P-G-V-G-H-N-L-Q-E-H-S-V-V-M-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-S-V-G-V-A-G-R-K-Q-S-R-S-K-Y-G-A-K-R-P-S"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It specifically binds to its receptor SecA Also required for the secretion of HasA via an ABC transporter system ### SEQUENCE -M-S-E-Q-N-S-T-E-M-A-F-Q-I-Q-R-I-Y-T-K-D-I-S-F-E-A-P-N-A-P-Q-V-F-Q-Q-E-W-Q-P-E-V-K-L-D-L-D-T-A-S-S-Q-L-A-D-E-V-Y-E-V-V-L-R-V-T-V-T-A-T-L-G-E-E-T-A-F-L-C-E-V-Q-Q-A-G-I-F-S-V-A-G-I-E-G-T-Q-L-A-H-C-L-G-A-Y-C-P-N-I-L-F-P-Y-A-R-E-C-I-T-S-L-V-S-R-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-M-N-Y-L-Q-Q-Q-A-E-G-E-G-A-A-P-H-Q-D-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-I-E-A-Q-V-G-K-R-Y-A-E-A-I-Y-G-I-A-E-A-N-N-K-V-K-E-L-Y-D-S-L-N-I-V-M-E-L-Y-K-G-D-K-E-F-K-N-L-V-D-H-P-L-V-K-K-E-E-K-K-E-F-I-N-K-V-F-S-E-F-E-K-F-S-L-D-I-L-C-Y-L-V-E-K-N-R-L-S-Y-I-R-G-V-V-A-E-Y-L-K-I-Y-Y-T-K-N-R-I-V-D-V-E-A-T-F-A-I-E-P-S-E-K-Q-K-A-K-L-I-E-K-L-E-K-K-T-G-K-K-V-N-L-V-I-K-I-N-K-A-I-I-A-G-G-I-I-K-I-G-D-E-I-I-D-G-S-V-R-R-Q-L-D-T-V-A-R-G"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-F-K-E-Y-K-I-Y-K-F-F-E-Q-V-K-Q-E-A-Y-K-V-V-W-P-T-K-K-E-L-T-A-S-T-L-V-V-I-V-A-V-F-V-F-S-L-I-C-L-V-L-D-Y-G-I-H-N-I-I-Q-I-L-L-N-I-G-K"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-F-K-E-Y-K-I-Y-K-F-F-E-Q-V-K-Q-E-T-Y-K-V-V-W-P-T-R-K-E-L-V-A-S-T-L-V-V-V-V-A-V-F-I-F-S-P-I-C-L-V-L-D-Y-S-I-H-N-I-M-Q-L-L-L-N-I-G-K"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-F-K-E-Y-K-I-Y-K-F-F-E-Q-V-K-Q-E-T-Y-K-V-V-W-P-T-R-K-E-L-V-A-S-T-L-V-V-V-V-A-V-F-I-F-S-L-T-C-L-V-L-D-Y-S-I-H-N-I-M-Q-L-L-L-N-I-G-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-Q-K-K-H-P-Q-G-N-I-A-Q-N-K-K-A-L-H-D-Y-F-I-E-Q-K-F-E-A-G-L-A-L-S-G-W-E-V-K-S-L-R-A-G-K-A-Q-L-V-D-S-Y-V-L-L-K-D-G-E-A-W-L-M-G-S-H-I-T-P-L-K-T-A-S-T-H-V-I-A-D-P-T-R-T-R-K-L-L-L-H-K-R-E-L-G-R-L-F-G-S-V-Q-Q-K-G-Y-A-C-V-A-L-S-L-Y-W-K-K-H-L-I-K-C-E-I-A-L-A-K-G-K-K-E-Y-D-K-R-D-T-E-K-A-R-D-S-D-R-E-I-Q-R-A-I-R-S-K-G-K-E-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-N-D-D-I-V-S-R-I-A-S-M-T-A-L-E-L-S-D-L-V-G-L-L-E-Q-R-F-N-I-S-R-I-A-P-A-P-C-Q-P-G-S-N-A-V-E-A-E-Q-D-R-R-D-R-K-V-F-L-T-H-S-G-S-N-K-I-A-V-I-R-A-V-R-D-V-T-K-L-G-L-K-E-S-K-G-L-V-D-S-A-P-S-L-V-A-E-G-L-S-A-D-E-A-E-D-I-R-A-K-V-E-A-A-G-A-K-A-E-V-R"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-S-K-I-R-P-L-G-D-R-V-V-V-K-R-S-E-D-E-T-K-T-P-C-G-I-V-I-P-D-S-A-A-E-K-Q-D-Q-G-T-V-V-A-L-G-P-G-K-K-D-S-E-G-A-R-V-P-M-E-V-R-L-G-D-R-V-L-F-G-K-Y-A-G-Q-S-I-K-V-D-D-E-D-L-M-V-M-R-E-E-D-I-V-A-V-I-E"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-A-K-K-Q-M-A-M-I-E-K-Y-A-D-K-R-Q-E-L-K-A-A-G-D-R-T-A-L-A-K-L-P-R-D-S-N-P-N-R-L-R-L-R-D-Q-T-D-G-R-P-R-G-Y-M-R-K-F-G-M-S-R-I-K-F-R-E-L-A-H-Q-G-L-I-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION Major structure protein of the hrp pilus, which is a component of the type III secretion system ### SEQUENCE -M-G-L-S-N-A-A-S-L-A-S-M-Q-T-L-D-K-A-M-A-S-A-T-A-M-T-T-A-A-Q-A-Q-K-V-Q-T-D-A-I-S-S-I-T-D-G-Q-M-D-S-A-S-K-A-M-N-S-G-Q-K-A-A-K-A-I-Q-F"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-V-A-I-M-T-E-T-V-A-I-A-N-A-A-A-E-R-Q-N-A-T-K-I-V-G-L-T-M-R-I-G-A-I-S-G-V-V-P-E-A-L-S-F-A-F-E-A-V-A-G-G-T-L-A-E-Q-A-Q-L-I-I-E-T-V-P-V-T-C-Y-C-A-Q-C-D-R-P-F-T-P-P-D-L-F-Y-E-C-P-L-C-S-S-L-S-Q-H-I-L-S-G-K-E-V-E-L-K-S-L-E-V-I"} +{"text": "### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-T-I-I-R-K-Y-H-I-A-I-A-W-T-I-A-T-S-A-M-L-I-S-L-I-F-S-E-W-M-K-L-P-P-C-D-L-C-W-Y-Q-R-M-A-M-Y-P-L-V-L-I-L-G-I-G-M-Y-R-K-D-S-N-V-S-I-Y-A-F-P-F-A-C-I-G-L-I-I-S-V-Y-Q-I-T-I-Q-A-F-P-T-S-E-M-K-I-C-S-V-G-V-S-C-T-E-N-Y-L-N-L-F-G-F-I-S-I-P-M-L-S-F-V-G-F-L-A-I-I-I-L-L-Y-I-N-Q-I-K-R-Q-K-N-K"} +{"text": "### FUNCTION May act as a membrane anchor for the tetrachloroethene reductive dehalogenase PceA ### SEQUENCE -M-N-I-Y-D-V-L-I-W-M-A-L-G-M-T-A-L-L-I-Q-Y-G-I-W-R-Y-L-K-G-K-G-K-D-T-I-P-L-Q-I-C-G-F-L-A-N-F-F-F-I-F-A-L-A-W-G-Y-S-S-F-S-E-R-E-Y-Q-A-I-G-M-G-F-I-F-F-G-G-T-A-L-I-P-A-I-I-T-Y-R-L-A-N-H-P-A-K-K-I-R-E-S-S-D-S-I-S-A"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-E-D-I-E-I-D-L-D-D-L-E-R-R-M-K-G-A-M-D-S-L-R-A-E-F-A-S-L-R-T-G-R-A-S-A-S-M-V-E-P-V-Q-V-E-A-Y-G-Q-M-T-P-I-N-Q-V-G-T-V-N-V-P-E-P-R-M-V-T-I-N-V-W-D-K-G-M-V-G-K-V-E-K-A-I-R-E-S-G-L-G-I-N-P-Q-T-N-G-T-I-I-M-L-P-I-P-E-L-N-E-E-R-R-R-E-L-T-K-V-A-A-Q-Y-A-E-H-A-R-V-A-I-R-N-V-R-R-D-G-M-D-Q-I-K-K-G-K-A-N-G-M-P-E-D-D-Q-K-F-W-E-T-A-V-Q-E-L-T-D-K-S-I-G-N-V-D-Q-A-L-E-A-K-Q-A-E-I-M-Q-V"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-S-D-I-Q-T-L-S-F-E-E-A-M-R-E-L-E-A-T-V-G-K-L-E-T-G-E-A-T-L-E-D-S-I-A-L-Y-E-R-G-A-A-L-R-A-H-C-E-T-R-L-R-E-A-E-E-R-V-E-K-I-T-L-A-A-N-G-Q-P-S-G-T-E-P-A-E-G-L"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-E-N-N-E-P-V-V-E-T-P-E-A-Q-N-D-L-P-E-V-E-R-L-K-G-E-V-E-F-L-K-A-E-L-E-A-S-K-N-K-F-L-R-L-Y-A-D-F-E-N-Y-K-K-R-M-V-Q-E-L-E-A-A-Q-R-N-G-K-F-D-A-V-R-A-L-L-G-T-L-D-D-L-E-R-A-L-G-F-A-S-V-K-P-E-D-L-I-P-G-V-R-S-V-L-E-N-F-T-R-S-L-K-S-L-G-V-E-A-V-P-G-V-G-A-E-F-D-P-R-Y-H-E-A-I-G-A-V-E-G-E-E-G-K-V-M-H-V-Y-Q-Q-G-F-K-Y-G-D-L-L-V-R-P-A-R-V-V-V-G-S-G-A-K-P-E-E-A-E-A"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-A-I-S-I-N-V-S-T-V-K-P-L-G-D-R-V-F-V-K-V-S-A-S-E-E-K-T-A-G-G-I-L-L-P-D-T-A-K-E-K-P-Q-I-G-E-I-V-T-V-G-P-G-K-R-N-D-D-G-S-R-S-E-P-E-V-K-V-G-D-K-V-L-Y-S-K-Y-A-G-T-D-I-K-L-G-G-E-D-Y-V-L-L-S-E-K-D-I-L-A-V-V-D"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-D-K-E-K-D-A-V-I-V-D-E-T-E-H-V-D-V-D-S-K-E-S-K-K-E-K-K-T-K-Q-Q-Q-K-I-E-F-L-E-A-E-V-K-E-L-N-D-K-Y-L-R-T-L-A-E-A-E-N-F-K-K-R-I-Q-A-E-K-I-M-D-R-K-Y-A-A-S-S-F-A-T-E-L-L-V-P-Y-E-Q-F-S-K-I-V-D-F-P-S-D-N-E-L-L-N-N-F-L-I-G-F-K-M-I-R-D-Q-F-K-S-V-L-E-N-E-G-V-V-E-I-K-A-L-G-E-V-F-D-A-K-V-H-H-A-I-E-K-E-S-N-K-D-K-P-N-G-T-V-L-E-V-L-Q-N-G-Y-L-F-K-D-R-I-L-R-P-A-M-V-K-I-N-E-W-S-E-D-N-G-E-D-K"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations ### SEQUENCE -M-S-W-Q-A-Y-V-D-E-H-L-M-C-E-I-D-G-H-H-L-T-A-A-A-I-L-G-H-D-G-S-V-W-A-Q-S-S-S-F-P-Q-F-K-S-E-E-I-T-N-I-M-N-D-F-N-E-P-G-S-L-A-P-T-G-L-Y-L-G-S-T-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-S-G-G-V-T-V-K-K-T-N-Q-A-L-I-F-G-I-Y-E-E-P-M-T-P-G-Q-C-N-M-V-V-E-R-L-G-D-Y-L-I-E-Q-G-M"} +{"text": "### FUNCTION Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites ### SEQUENCE -M-E-E-K-W-K-L-S-K-K-D-T-T-A-S-S-S-S-S-K-S-K-F-S-R-S-F-S-T-S-A-S-S-T-K-S-P-I-F-V-R-S-S-S-T-K-C-S-V-P-S-S-S-S-S-S-S-S-S-S-S-I-S-R-S-F-S-R-K-E-R-R-S-S-S-S-S-S-S-S-I-T-Q-K-Y-S-S-L-A-K-E-Q-K-A-R-F-Y-I-M-R-R-C-V-A-M-L-V-C-W-H-K-H-G-D-S"} +{"text": "### FUNCTION Mediates the uptake of pyruvate into mitochondria ### SEQUENCE -M-A-T-S-K-L-Q-A-L-W-N-H-P-A-G-P-K-T-I-H-F-W-A-P-T-F-K-W-G-I-S-I-A-N-I-A-D-F-Q-K-P-P-E-N-I-S-Y-L-Q-Q-I-A-V-T-C-T-G-M-I-W-C-R-C-S-T-I-I-T-P-K-N-W-N-L-F-S-V-N-V-A-M-A-A-T-G-I-Y-Q-L-T-R-K-I-K-Y-D-Y-V-S-E-A-E-A-A-V-E-I-E-G"} +{"text": "### FUNCTION Involved in the assembly of mitochondrial iron-sulfur proteins Probably involved in the binding of an intermediate of Fe/S cluster assembly ### SEQUENCE -M-R-K-Q-V-L-A-L-S-D-T-A-A-A-R-I-R-Q-L-L-Q-H-Q-Q-K-P-F-L-R-L-A-V-E-A-K-G-C-N-G-L-S-Y-V-L-N-Y-A-Q-E-K-G-K-F-D-E-V-V-E-E-K-G-V-K-I-L-V-D-P-K-A-V-M-H-V-I-G-T-E-M-D-F-V-D-D-K-L-R-S-E-F-V-F-V-N-P-N-A-T-K-C-G-C-G-E-S-F-T-T-T"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-F-D-D-Q-D-L-G-F-F-A-N-F-L-G-I-F-I-F-I-M-V-I-A-Y-H-F-V-V-A-E-P-K-F-E"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-M-Q-E-L-G-L-Q-R-F-S-N-D-V-V-R-L-D-L-T-P-P-S-Q-T-S-S-T-S-L-S-I-D-E-E-E-S-T-E-A-K-I-R-R-L-I-S-E-H-P-V-I-I-F-S-R-S-S-C-C-M-C-H-V-M-K-R-L-L-A-T-I-G-V-I-P-T-V-I-E-L-D-D-H-E-V-S-S-L-P-T-A-L-Q-D-E-Y-S-G-G-V-S-V-V-G-P-P-P-A-V-F-I-G-R-E-C-V-G-G-L-E-S-L-V-A-L-H-L-S-G-Q-L-V-P-K-L-V-Q-V-G-A-L-W-V"} +{"text": "### FUNCTION Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane ### SEQUENCE -M-E-T-T-K-S-N-S-S-E-S-D-V-N-A-K-W-D-A-C-L-D-L-T-A-R-R-F-V-Y-S-S-L-G-G-A-F-A-G-L-L-F-F-R-S-P-V-T-R-W-A-S-I-A-F-G-A-G-I-G-I-G-S-A-Y-T-D-C-S-R-V-F-D-A-S-S-S-T-S-A-T-L-L-A-A-P-K-S-T-E-T-S-V-S-Q-A-A-E-E"} +{"text": "### FUNCTION Elicitor of plant defense ### SEQUENCE -M-E-N-L-R-N-G-E-D-N-G-S-L-I-P-F-T-F-F-D-Q-S-S-V-T-I-P-L-L-K-C-S-G-L-E-S-S-S-S-S-S-S-S-C-D-L-S-S-S-H-S-E-E-D-E-S-I-D-I-K-E-E-E-E-E-E-E-E-D-G-M-T-I-E-I-K-A-R-G-K-N-K-T-K-P-T-P-S-S-G-K-G-G-K-H-N"} +{"text": "### FUNCTION Variable subunit of the ferredoxin-thioredoxin reductase , which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin ### SEQUENCE -M-T-N-S-Y-A-L-S-P-A-I-I-A-A-V-R-P-P-A-S-Q-D-Y-L-V-A-A-S-L-S-G-R-K-S-I-N-S-S-S-S-S-I-F-V-P-I-S-L-S-T-S-Y-G-R-S-K-C-A-F-S-I-S-R-K-N-P-K-S-T-I-R-C-D-I-A-V-K-S-A-A-S-V-D-A-D-A-D-L-S-S-S-T-S-L-E-T-E-E-D-E-K-A-K-E-K-I-G-A-R-V-R-V-T-V-P-L-K-V-Y-H-V-V-R-V-P-E-V-E-L-M-G-M-E-G-F-I-K-D-Y-V-V-L-W-K-G-K-K-I-S-A-N-L-P-F-K-V-Q-F-V-K-E-I-E-G-R-G-P-V-K-F-F-T-H-L-K-E-D-E-F-E-L-I-D-P"} +{"text": "### FUNCTION Probable thiol-disulfide oxidoreductase that may participate in various redox reactions ### SEQUENCE -M-R-K-Q-E-S-E-G-A-N-L-E-F-E-S-K-S-N-D-N-G-N-V-K-I-A-P-N-D-Q-S-F-L-T-I-L-D-D-I-K-S-S-K-S-P-A-V-I-N-Y-G-A-S-W-C-G-V-C-S-Q-I-L-P-A-F-R-K-L-S-N-S-F-S-K-L-K-F-V-Y-A-D-I-D-E-C-P-E-T-T-R-H-I-R-Y-T-P-T-F-Q-F-Y-R-D-G-E-K-V-D-E-M-F-G-A-G-E-Q-R-L-H-D-R-L-W-L-H-S"} +{"text": "### FUNCTION May regulate transcription elongation by RNA polymerase II May enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex ### SEQUENCE -M-G-E-A-P-A-Q-I-P-T-S-F-G-H-E-L-R-A-C-L-R-C-R-L-V-K-T-Y-D-Q-F-R-D-S-G-C-E-N-C-P-F-F-K-I-E-D-D-H-E-R-I-V-D-V-T-T-P-N-F-N-G-I-I-S-M-M-D-P-R-R-S-W-A-A-R-W-L-R-I-G-K-F-A-P-G-C-Y-T-L-A-V-S-E-A-L-P-E-E-M-Q-F-I-C-Q-Q-A-R-V-Q-Y-V-P-P-K-R-I"} +{"text": "### FUNCTION Elicitor of plant defense ### SEQUENCE -M-Q-Q-E-R-D-H-K-R-D-C-C-K-L-M-P-Q-T-V-K-A-F-F-K-C-L-R-F-R-R-S-S-S-S-S-S-D-M-V-K-A-R-A-R-N-E-E-K-E-E-P-S-S-I-E-T-S-T-R-S-L-N-V-M-R-K-G-I-R-K-Q-P-V-S-S-G-K-R-G-G-V-N-D-Y-D-M"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-G-G-G-G-H-G-G-G-I-T-Y-K-G-V-T-V-H-T-P-K-T-W-H-T-V-T-G-K-G-L-C-A-V-M-W-F-W-I-L-Y-R-A-K-Q-D-G-P-V-V-M-G-W-R-H-P-W-D-G-H-G-D-H-G-H-G-D-H-H"} +{"text": "### FUNCTION Extracellular signal peptide that regulates cell fate ### SEQUENCE -M-R-R-H-D-I-I-I-K-L-L-L-L-M-C-L-L-L-S-R-F-V-T-R-E-C-Q-E-V-H-F-K-I-G-P-A-K-I-I-A-K-P-N-N-A-R-V-M-P-T-W-G-E-E-K-K-W-H-K-H-P-S-G-P-N-P-T-G-N-R-H-P-P-V-K-H"} +{"text": "### FUNCTION Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites ### SEQUENCE -M-D-D-E-N-L-W-K-V-V-K-K-D-S-I-F-E-T-T-H-F-S-S-K-P-V-F-T-R-S-F-S-T-K-T-S-S-S-S-S-K-P-V-F-T-R-S-F-S-T-K-P-T-S-Y-S-S-S-E-P-I-F-R-R-S-F-S-A-K-P-T-S-S-K-S-P-F-L-S-R-S-G-S-T-K-C-P-V-D-T-S-S-T-S-K-C-S-I-S-R-S-L-S-Q-K-G-A-S-V-T-R-K-C-R-N-M-A-K-E-H-K-S-R-F-Y-I-M-K-R-C-V-L-M-L-V-C-W-H-K-H-A-C-D-S"} +{"text": "### FUNCTION Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions ### SEQUENCE -M-G-K-R-K-S-R-A-K-P-A-P-T-K-R-M-D-K-L-D-T-I-F-S-C-P-F-C-N-H-G-S-S-V-E-C-I-I-D-M-K-H-L-I-G-K-A-A-C-R-I-C-E-E-S-F-S-T-T-I-T-A-L-T-E-A-I-D-I-Y-S-E-W-I-D-E-C-E-R-V-N-T-A-E-D-D-V-V-Q-E-E-E-E-E-V-E-E-E-E-E-E-E-E-E-E-D-D-E-D-D-H-V-S-V-K-R-K-Y-N-F"} +{"text": "### FUNCTION Acts redundantly with SPR1 in maintaining the cortical microtubules organization essential for anisotropic cell growth ### SEQUENCE -M-S-R-G-G-S-F-G-G-G-Q-S-S-L-G-Y-L-F-G-S-D-N-E-I-P-K-T-P-A-P-P-V-A-P-K-P-A-P-P-Y-G-V-D-S-T-E-E-D-H-E-A-D-Q-K-P-K-I-S-N-N-N-Y-Q-R-V-Q-G-Q-N-S-G-N-F-V-T-D-R-P-T-T-K-V-K-S-V-P-G-G-G-S-S-L-G-Y-L-F-G-D-K"} +{"text": "### FUNCTION Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions ### SEQUENCE -M-G-K-R-K-S-A-A-K-P-P-P-K-K-R-M-D-K-L-D-T-V-F-S-C-P-F-C-N-H-G-S-S-V-E-C-R-I-D-M-K-N-L-I-G-E-A-S-C-R-I-C-Q-E-N-F-S-T-T-V-N-A-L-T-E-P-I-D-I-Y-S-E-W-I-D-E-C-E-R-V-N-N-V-E-D-D-D-G-A"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-V-Y-Q-D-K-L-S-G-D-E-L-L-S-D-S-F-P-Y-R-E-L-E-N-G-V-L-W-E-V-D-G-H-W-V-V-Q-G-A-V-D-V-D-I-G-A-N-P-S-A-E-G-G-G-D-D-E-G-V-D-D-Q-A-V-K-V-V-D-I-V-D-T-F-R-L-Q-E-Q-P-A-F-D-K-K-Q-F-I-S-H-M-K-R-Y-I-K-N-L-S-A-K-L-E-G-D-D-L-D-V-F-K-K-N-V-E-S-A-T-K-Y-L-L-S-K-L-K-D-L-Q-F-F-V-G-E-S-M-H-D-D-G-G-V-V-F-A-Y-Y-K-E-G-A-A-D-P-T-F-L-Y-F-A-H-G-L-K-E-V-K-C"} +{"text": "### FUNCTION Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans Host outer membrane disruption is possibly due to local fusion between the inner and outer membrane performed by the spanin complex ### SEQUENCE -M-R-T-K-I-F-A-A-G-T-V-L-T-C-L-M-L-C-A-G-C-T-S-A-P-P-A-P-T-P-V-I-V-P-N-A-C-P-K-V-S-L-C-P-M-P-G-S-D-P-Q-T-N-G-D-L-S-A-D-I-R-Q-L-E-N-A-L-A-R-C-A-S-Q-V-K-M-I-K-H-C-Q-D-E-N-D-A-Q-T-R-Q-P-A-Q-G-A-D"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-L-K-K-N-P-F-V-A-N-H-L-L-R-K-I-N-K-L-N-T-K-A-E-K-D-I-I-L-T-W-S-R-A-S-T-I-I-P-T-M-I-G-H-T-I-A-I-H-N-G-K-E-H-L-P-I-Y-I-T-D-R-M-V-G-H-K-L-G-E-F-S-P-T-L-N-F-R-G-H-A-K-N-D-N-R-S-R-R"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-Q-S-N-P-N-E-Q-T-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-N-G-I-K-Y-A-V-F-T-D-K-S-I-R-L-L-G-K-N-Q-Y-T-F-N-V-E-S-G-S-T-R-T-E-I-K-H-W-V-E-L-F-F-D-V-K-V-I-A-M-N-S-H-R-L-P-V-K-G-R-R-V-R-P-I-M-G-H-T-M-H-Y-R-R-M-I-I-T-L-Q-P-G-Y-S-I-P-P-L-R-K-K-R-T"} +{"text": "### FUNCTION This protein binds to 23S rRNA ### SEQUENCE -M-S-T-Y-A-I-I-D-L-G-G-K-Q-L-R-V-E-P-G-R-F-Y-D-A-H-L-F-S-S-F-K-S-L-L-S-E-S-N-T-K-I-I-I-F-R-V-L-M-I-S-H-G-T-E-V-Q-F-G-Y-P-W-L-K-N-A-S-V-K-A-R-I-L-H-K-K-Q-N-D-K-M-L-I-Y-K-M-R-S-K-K-K-T-R-K-K-F-G-H-R-Q-K-I-A-R-F-I-V-D-A-I-Q-Y-N-G-Q-T-F-T-T-N-L-K"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-D-K-V-K-S-P-L-L-T-E-K-S-I-R-L-L-Q-K-N-Q-Y-T-F-Q-V-N-S-D-V-N-K-T-E-F-K-K-W-I-E-I-F-F-K-V-K-V-M-S-I-N-S-C-R-P-P-R-K-K-K-R-I-G-L-I-S-G-Y-T-V-R-Y-K-K-I-I-V-T-L-K-S-G-D-S-I-P-L-F-S-I"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-I-K-K-G-P-F-V-A-D-H-L-I-K-K-I-E-N-L-N-A-K-G-E-K-K-V-I-I-T-W-S-R-A-S-T-I-V-P-M-M-I-G-H-T-I-A-V-H-N-G-R-E-H-L-P-V-F-V-T-D-R-M-V-G-Q-K-L-G-E-F-S-P-T-R-T-F-R-G-H-V-K-S-D-K-K-S-R-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-I-N-N-T-N-S-N-I-S-I-K-A-V-G-K-K-I-R-I-S-P-H-K-M-R-K-V-I-D-Q-I-R-G-R-S-Y-E-Q-A-L-M-I-L-E-F-M-P-Y-K-A-C-N-Y-V-L-K-L-L-S-S-V-A-A-N-A-N-H-N-F-G-L-N-K-S-D-L-F-I-E-K-I-I-A-D-G-G-P-K-L-K-R-F-Q-P-R-A-Q-G-R-G-Y-P-I-L-K-P-T-C-N-L-M-I-V-V-K-V-K-S"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-P-Q-S-Y-L-N-V-A-D-N-S-G-A-R-K-I-M-C-I-R-I-L-G-G-S-N-K-K-Y-G-H-I-G-D-T-I-I-G-V-V-K-E-A-I-P-N-M-T-L-K-K-S-E-V-V-R-A-V-I-V-R-T-C-K-E-L-K-R-K-N-G-T-I-L-R-F-D-E-N-A-A-V-I-I-N-Q-E-G-N-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-A-N-F-T-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION Binds 5S rRNA, forms part of the central protuberance of the 50S subunit ### SEQUENCE -M-V-Q-R-L-K-S-I-Y-L-N-N-V-I-P-K-L-N-E-E-A-K-Y-K-N-V-H-Q-I-P-R-L-K-K-I-V-I-N-C-G-I-G-E-A-S-Q-N-A-K-T-L-E-Y-T-I-R-D-L-S-I-I-A-G-Q-R-P-L-V-K-R-A-K-K-A-I-A-S-F-Q-L-R-K-K-M-P-V-G-V-S-V-T-L-R-G-D-A-M-Y-A-F-L-D-R-L-I-N-L-A-L-P-R-I-R-D-F-Q-G-L-N-R-K-S-F-D-G-H-G-N-F-H-L-G-L-K-E-Q-L-M-F-P-E-I-D-Y-D-K-I-D-K-L-R-G-M-D-I-C-I-V-T-T-C-T-N-D-N-E-C-F-Q-F-L-S-A-L-G-M-P-F-Q-T-V-S-S-K-K-L"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-K-Q-N-L-I-E-M-E-G-I-V-T-E-S-L-P-N-A-M-F-R-V-S-L-D-N-G-C-Q-V-L-A-H-I-S-G-K-I-R-R-N-Y-I-R-I-L-P-G-D-K-V-K-V-E-L-S-P-Y-D-L-T-K-G-R-I-T-Y-R-L-R-M-K-T-T-N-G"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-Q-R-N-D-N-F-I-D-K-T-F-T-V-V-A-D-I-L-L-R-V-I-P-T-T-R-R-E-K-E-A-F-S-Y-Y-R-D-G-M-S-A-Q-S-E-G-E-Y-A-E-A-L-Q-N-Y-Y-E-A-M-R-L-E-I-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-Q-H-T-K-A-L-E-Y-Y-L-Q-A-L-E-R-N-P-A-L-P-Q-A-F-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-Q-Q-G-D-P-E-N-A-E-A-W-F-D-Q-A-A-D-Y-W-K-Q-G-I-A-L-A-P-S-N-Y-I-E-A-Q-N-W-L-K-I-T-G-R-L-K-A"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -M-I-L-A-F-Q-L-S-V-F-A-L-V-A-I-S-F-L-L-V-V-G-V-P-V-V-L-A-S-P-D-G-W-S-T-S-K-N-A-V-F-S-G-A-S-L-W-I-A-L-V-F-L-V-G-V-L-N-S-F-I-S"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-T-P-N-P-N-K-Q-S-V-E-L-N-R-T-S-L-F-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-N-V-G-T-T-G-R-I-P-L-W-I-I-G-T-L-A-G-T-L-V-I-G-L-L-A-I-F-F-Y-G-S-Y-V-G-L-G-S-S-L"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-N-I-K-S-E-F-F-R-V-D-F-I-I-G-A-R-R-L-S-N-Y-F-W-A-T-V-V-F-L-G-S-L-G-F-F-I-V-G-V-S-S-Y-L-Q-K-N-I-V-F-F-L-S-A-S-D-I-L-F-T-P-Q-G-I-V-M-C-F-Y-G-I-A-G-L-F-L-S-F-Y-L-W-F-T-I-F-L-D-I-G-S-G-Y-N-E-F-D-K-K-K-G-I-I-S-I-F-R-W-G-Y-P-G-Q-N-R-R-I-K-L-S-F-P-I-K-D-V-Q-A-I-K-L-E-V-K-E-V-L-P-A-R-R-M-I-Y-I-K-I-K-G-Q-Q-D-I-P-L-N-R-I-A-E-N-I-T-L-R-E-M-E-D-K-A-A-D-L-A-R-F-L-K-V-S-I-E-G-L"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-A-A-S-F-L-P-S-I-L-V-P-L-V-G-L-V-F-P-A-I-A-I-A-S-L-F-I-Y-I-E-Q-D-E-I-I"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-L-N-I-R-V-M-A-P-N-R-I-V-W-N-S-E-A-Q-E-I-I-L-S-T-N-S-G-Q-I-G-I-L-P-N-H-A-P-L-L-T-A-L-D-I-G-I-M-R-I-L-V-N-G-Q-W-T-S-M-A-L-M-G-G-F-A-L-V-D-N-N-Q-L-T-I-L-V-N-E-A-E-K-A-S-E-I-D-P-K-E-A-E-N-N-F-E-L-A-K-Q-N-L-A-A-A-E-G-R-K-Q-I-I-E-A-N-L-S-F-Q-R-A-K-A-R-L-D-A-V-N-A-S-S-R-L-G"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-K-K-S-I-I-H-R-D-K-K-R-E-N-L-V-K-K-Y-Q-E-I-R-N-S-I-K-E-N-I-K-Q-A-K-S-L-N-E-K-W-E-L-Q-K-Q-L-Q-A-L-P-R-N-S-S-P-T-R-I-H-R-R-C-F-V-T-G-R-P-R-A-V-Y-R-D-F-G-L-S-R-H-V-I-R-E-M-A-H-S-C-L-L-P-G-V-T-K-S-S-W"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex ### SEQUENCE -M-I-S-I-L-T-Y-F-G-I-L-F-G-I-L-T-I-T-V-I-I-F-V-A-L-N-K-I-Q-L-I"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-V-E-P-L-L-S-G-I-V-L-G-L-I-P-I-T-L-A-G-L-F-V-T-A-Y-L-Q-Y-R-R-G-D-Q-L-D-F"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-Q-Y-F-K-T-Y-L-S-T-A-P-V-I-A-T-I-W-F-G-F-L-A-G-L-L-I-E-I-N-R-F-F-P-D-A-L-V-L-P-Y-L"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-V-K-R-G-Y-V-A-R-R-R-R-K-K-I-L-H-L-T-S-G-F-Y-G-A-H-S-R-L-F-R-V-A-N-Q-K-A-I-R-A-L-A-Y-S-H-I-D-R-A-K-R-K-R-N-M-R-S-L-W-I-C-R-I-N-A-V-A-R-E-Q-N-I-S-Y-S-Y-L-I-K-S-L-K-E-K-K-I-L-L-N-R-K-M-L-A-Q-L-A-V-L-D-K-P-S-F-I-K-L-I-N-T-H-L-N"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-G-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-R-V-P-V-K-D-K-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-G-I-L-V-V-I-F-I-S-C-L-L-V-S-F-T-G-Y-T-I-Y-T-A-F-G-Q-P-S-K-Q-L-R-D-P-F-E-E-H-E-D"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-G-V-T-K-K-P-D-L-S-D-P-V-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-V-C-I-F-G-T-I-A-C-T-V-G-L-S-V-L-E-P-V-I-V-G-E-P-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-F-P-V-F-Q-I-L-R-T-V-P-N-K-L-L-G-V-L-L-M-A-G-V-P-V-G-L-L-T-V-P-F-I-E-N-V-N-K-F-Q-N-P-F-R-R-P-V-A-T-T-V-F-L-L-G-T-V-V-A-I-W-L-G-I-G-A-A-L-P-I-D-T-S-L-T-L-G-L-F"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-L-E-I-L-A-Q-L-T-A-L-A-F-I-V-V-S-G-P-L-V-I-A-L-L-A-F-R-K-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-I-F-V-Y-T-V-V-I-F-F-V-S-L-F-I-F-G-F-L-S-N-D-P-A-R-N-P-G-R-K-E-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-N-M-I-S-T-F-F-D-S-S-S-N-F-S-E-A-F-L-A-K-L-P-E-A-Y-A-I-F-D-P-I-V-D-V-M-P-I-I-P-V-F-F-L-L-L-A-F-V-W-Q-A-A-V-S-F-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-Y-I-Y-M-N-I-E-K-I-F-S-I-A-L-K-T-W-P-I-G-N-S-F-A-I-N-T-N-I-L-E-T-N-L-I-N-L-G-V-V-L-A-I-L-V-Y-F-G-K-G-I-L-S-N-L-L-E-N-R-K-Q-N-I-L-S-T-I-R-D-A-E-Q-C-Y-Q-E-A-A-A-K-L-K-Q-A-K-L-R-L-E-Q-A-K-L-K-A-D-E-I-R-I-Q-G-L-A-Q-L-E-R-E-K-L-E-L-I-K-A-A-D-E-D-S-K-R-L-E-E-S-K-N-V-T-I-R-F-E-Q-Q-R-A-I-E-Q-V-R-Q-Q-V-S-R-L-A-L-E-R-A-L-E-T-L-N-N-S-L-N-P-D-L-Q-A-R-I-I-D-N-H-I-G-L-L-R-T-I-E-G-V-T-E-S"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-L-I-T-I-T-W-A-S-V-M-V-A-F-T-F-S-L-S-L-V-V-W-G-R-S-G-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-V-I-A-T-A-L-F-V-L-I-P-T-A-F-L-L-I-L-Y-V-K-T-E-S-A-G-S"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-I-Q-Q-L-I-R-N-R-R-E-P-I-E-N-R-T-K-S-P-A-L-R-S-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-S-V-G-V-K-D-R-H-Q-G-R-S-K-Y-G-A-K-K-P-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-Q-S-N-P-N-E-Q-T-V-E-L-N-R-T-I-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-C-R-P-R-R-R-C-R-R-R-R-R-R-S-C-R-A-R-R-R-A-T-R-C-C-R-R-R-Y-R-L-S-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-R-C-R-S-Q-S-R-S-R-C-C-R-P-R-R-R-C-R-R-R-R-R-Q-S-C-R-A-R-R-R-A-T-R-C-C-R-R-R-Y-R-L-R-C-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-C-R-R-R-R-R-C-R-R-R-R-R-Q-R-C-R-A-R-R-T-A-M-R-C-C-R-R-R-Y-R-R-R-C-R-R-Y"} +{"text": "### FUNCTION Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5 This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells ### SEQUENCE -M-Y-R-M-Q-L-L-S-C-I-A-L-S-L-A-L-I-T-N-S-A-P-T-S-S-S-T-K-K-T-Q-L-Q-L-E-H-L-L-L-D-L-Q-M-L-L-N-G-I-N-N-Y-K-N-P-K-L-T-R-M-L-T-F-K-F-Y-L-P-K-K-A-T-E-L-K-H-L-Q-C-L-E-E-E-L-K-P-L-E-E-V-L-N-L-A-Q-S-K-N-F-H-L-R-D-T-R-D-I-I-S-N-I-N-V-L-V-L-E-L-K-G-S-E-T-T-F-T-C-E-Y-D-D-D-T-A-T-I-I-E-F-L-N-G-W-I-T-F-C-Q-S-I-I-S-T-L-T"} +{"text": "### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-F-I-Y-R-L-V-F-I-A-P-L-I-L-L-L-F-S-L-A-K-A-R-H-P-F-D-I-F-H-W-N-W-Q-D-F-Q-E-C-L-Q-V-N-N-I-T-I-G-E-Y-E-K-Y-A-R-H-E-T-L-D-Y-L-L-N-E-K-V-D-L-R-Y-K-C-N-I-K-C-Q-L-E-R-D-S-T-K-W-L-N-A-Q-G-R-M-D-L-D-L-M-N-T-T-D-K-A-S-K-S-I-T-K-C-M-E-K-A-P-E-E-L-C-A-Y-S-F-R-L-V-M-C-A-F-K-A-G-H-P-V-I-D-S-E"} +{"text": "### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-F-N-T-R-L-A-I-F-L-L-L-I-V-V-S-L-S-Q-A-K-E-S-Q-P-F-D-F-F-E-G-T-Y-D-D-F-I-D-C-L-R-I-N-N-I-T-I-E-E-Y-E-K-F-D-D-T-D-N-L-D-N-V-L-K-E-N-V-E-L-K-H-K-C-N-I-K-C-Q-L-E-R-E-P-T-K-W-L-N-A-R-G-E-V-D-L-K-S-M-K-A-T-S-E-T-A-V-S-I-S-K-C-M-E-K-A-P-Q-E-T-C-A-Y-V-Y-K-L-V-I-C-A-F-K-S-G-H-S-V-I-K-F-D-S-Y-E-Q-I-Q-E-E-T-A-G-L-I-A-E-Q-Q-A-D-L-F-D-Y-D-T-I-D-L"} +{"text": "### FUNCTION May be involved in cytochrome c oxidase biogenesis ### SEQUENCE -M-L-P-D-L-S-P-H-L-H-T-K-E-C-N-M-L-I-E-F-L-Q-R-C-H-S-E-K-P-I-G-K-M-I-G-K-C-S-Y-W-D-E-A-V-W-Q-C-T-K-K-E-R-I-W-R-R-D-N-N-P-A-Y-K-R-R-I-V-E-L-R-S-L-P-E-K-Y-W-T-P-A-L-H-K-L-K-E-D-G-V-L-I-G-G-A-D-Q-S-Q-G-C-K-I"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-Q-N-R-P-K-S-V-L-T-P-A-R-L-G-T-S-G-V-V-R-N-T-L-E-D-P-W-V-R-F-Q-I-E-L-E-F-V-Q-S-L-G-N-P-D-Y-L-T-F-L-A-Q-Q-G-C-F-D-K-P-E-F-I-N-Y-L-S-Y-L-Q-Y-W-K-S-P-S-Y-S-R-F-I-T-Y-P-F-C-L-H-M-L-D-L-L-Q-S-P-D-F-R-R-E-V-A-H-E-S-V-T-R-F-I-D-D-Q-M-L-L-H-W-K-N-Y-L-R-K-R-A-E-M-V-N-K-H-V-Q-S-L-D-A-M-A-T-P-G-P-G-P-S-S"} +{"text": "### FUNCTION Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions ### SEQUENCE -M-G-R-R-K-S-K-R-K-P-P-P-K-R-K-N-I-E-P-L-D-Q-Q-F-N-C-P-F-C-N-H-E-K-S-C-E-V-K-M-D-K-S-R-N-T-A-K-I-T-C-R-V-C-L-E-D-F-Q-T-G-I-N-F-L-S-E-P-I-D-V-Y-N-D-W-V-D-A-C-E-T-A-N"} +{"text": "### FUNCTION Involved in transport from the endoplasmic reticulum to the Golgi apparatus ### SEQUENCE -M-G-F-G-D-W-F-K-S-A-L-S-F-L-G-L-Y-K-K-K-A-T-I-V-F-V-G-L-D-N-A-G-K-S-T-L-L-A-M-L-K-N-S-A-T-T-T-V-A-P-T-Q-Q-P-T-S-Q-E-L-V-M-G-S-I-R-F-K-T-F-D-L-G-G-H-E-V-A-R-Q-L-W-E-Q-Y-V-T-N-S-D-G-I-V-F-L-V-D-S-A-D-P-S-R-F-E-E-S-R-R-T-L-Q-E-L-L-D-N-H-D-L-A-T-T-P-I-L-I-L-S-N-K-V-D-I-Q-T-A-V-S-M-E-T-M-V-Q-S-F-G-I-Q-H-L-L-T-G-K-G-G-S-N-L-R-S-D-Q-R-P-L-E-V-F-P-C-S-V-I-N-R-F-G-Y-T-D-G-F-K-W-L-S-K-Y-L"} +{"text": "### FUNCTION Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria ### SEQUENCE -M-N-F-K-L-I-F-L-V-A-L-V-L-M-A-A-F-L-G-Q-T-E-G-R-R-F-K-K-F-L-K-K-V-E-G-A-G-R-R-V-A-N-A-A-Q-K-G-L-P-L-A-A-G-V-K-G-L-V-G"} +{"text": "### FUNCTION Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria ### SEQUENCE -M-N-F-T-K-L-F-I-L-V-A-I-A-V-L-V-V-V-G-V-Q-P-V-D-G-A-P-R-W-K-F-G-K-R-L-E-K-L-G-R-N-V-F-R-A-A-K-K-A-L-P-V-I-A-G-Y-K-A-L-G"} +{"text": "### FUNCTION Has antifungal activity against the entomopathogenic fungus Mnisopliae, but does not display any antifungal activity against Scerevisiae nor any antimicrobial activity against Mluteus, Bsubtilis, and Ecoli ### SEQUENCE -M-K-I-A-F-I-V-A-I-S-L-A-F-L-A-V-T-S-C-I-E-F-E-K-S-T-E-S-H-D-I-Q-K-R-G-V-T-I-T-V-K-P-P-F-P-G-C-V-F-Y-E-C-I-A-N-C-R-S-R-G-Y-K-N-G-G-Y-C-T-I-N-G-C-Q-C-L-R"} +{"text": "### FUNCTION May be required for cytochrome c complex assembly and function, COX being the terminal component of the mitochondrial respiratory chain ### SEQUENCE -M-S-S-I-S-S-S-S-S-N-V-R-M-D-R-R-F-D-W-V-G-P-P-D-N-L-S-K-I-R-K-I-M-L-R-R-V-D-N-E-S-E-L-E-R-Q-Y-R-L-A-R-E-E-L-N-Q-W-N-S-D-F-W-A-E-H-N-Q-L-F-D-R-Q-K-S-D-F-V-E-R-K-Q-Q-E-L-G-R-L-E-H-V-S-A-N-E-L-S-E-F-Y-R-D-F-L-N-D-R-H-V-A-M-M-A-Y-N-K-E-W-Y-R-R-N-L-Q-L-I-W-P-A-L-K-V-N-V-V-R-F-F-R-M-A-R-R"} +{"text": "### FUNCTION Highly acidic peptide that may have antibacterial activity ### SEQUENCE -M-S-S-K-T-L-L-V-L-L-L-V-G-V-L-V-S-T-F-F-T-A-D-A-Y-P-A-S-M-D-N-Y-D-D-A-L-E-E-L-D-N-L-D-L-D-D-Y-F-D-L-E-P-A-D-F-V-L-L-D-M-W-A-N-M-L-E-S-S-D-F-D-D-M-E"} +{"text": "### FUNCTION Microtubule inner protein in cilia axoneme, which is required for motile cilia beating ### SEQUENCE -M-F-L-T-A-V-N-P-Q-P-L-S-T-P-S-W-Q-I-E-T-K-Y-S-T-K-V-L-T-G-N-W-M-E-E-R-R-K-F-T-R-D-T-D-K-T-P-Q-S-I-Y-R-K-E-Y-I-P-F-P-D-H-R-P-D-Q-I-S-R-W-Y-G-K-R-K-V-E-G-L-P-Y-K-H-L-I-T-H-H-Q-E-P-P-H-R-Y-L-I-S-T-Y-D-D-H-Y-N-R-H-G-Y-N-P-G-L-P-P-L-R-T-W-N-G-Q-K-L-L-W-L-P-E-K-S-D-F-P-L-L-A-P-P-T-N-Y-G-L-Y-E-Q-L-K-Q-R-Q-L-T-P-K-A-G-L-K-Q-S-T-Y-T-S-S-Y-P-R-P-P-L-C-A-M-S-W-R-E-H-A-V-P-V-P-P-H-R-L-H-P-L-P-H-F"} +{"text": "### FUNCTION Substrate-recognition component of the SCF -type E3 ubiquitin ligase complex ### SEQUENCE -M-A-S-W-L-P-E-T-L-F-E-T-V-G-Q-G-P-P-P-S-K-D-Y-Y-Q-L-L-V-T-R-S-Q-V-I-F-R-W-W-K-I-S-L-R-S-E-Y-R-S-T-K-P-G-E-A-K-E-T-H-E-D-F-L-E-N-S-H-L-Q-G-Q-T-A-L-I-F-G-A-R-I-L-D-Y-V-I-N-L-C-K-G-K-F-D-F-L-E-R-L-S-D-D-L-L-L-T-I-I-S-Y-L-D-L-E-D-I-A-R-L-C-Q-T-S-H-R-F-A-K-L-C-M-S-D-K-L-W-E-Q-I-V-Q-S-T-C-D-T-I-T-P-D-V-R-A-L-A-E-D-T-G-W-R-Q-L-F-F-T-N-K-L-Q-L-Q-R-Q-L-R-K-R-K-Q-K-Y-G-N-L-R-E-K-Q-P"} +{"text": "### FUNCTION Accessory component of the V0 complex of vacuolar ### SEQUENCE -M-K-P-L-V-S-P-G-L-A-K-A-C-T-G-L-S-L-I-G-I-V-F-L-L-V-L-S-Y-L-F-S-I-E-A-E-T-L-M-H-D-L-V-G-S-G-L-T-G-K-Q-V-A-K-T-C-L-G-A-V-V-I-Y-A-V-F-F-L-F-C-G-S-Q-V-I-V-S-R-Y-Q-K-P-V-R-I"} +{"text": "### FUNCTION Facilitates protein transport into the nucleus Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import ### SEQUENCE -M-S-D-F-N-A-I-A-Q-Q-F-T-E-F-Y-Y-K-T-F-D-T-D-R-A-Q-L-A-P-L-Y-R-E-N-S-M-L-T-F-E-Q-S-P-F-L-G-T-A-N-I-V-G-K-L-Q-E-L-P-F-Q-R-I-E-H-Q-V-A-T-V-D-A-Q-P-S-N-E-S-G-G-I-L-V-V-V-S-G-A-L-L-V-E-E-E-R-R-P-M-S-Y-T-Q-T-F-Q-L-L-P-A-D-G-A-Y-Y-V-F-N-D-V-F-R-L-V-Y-P-A-A"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-L-P-A-Q-K-H-V-W-V-G-L-Q-S-I-Y-G-I-G-R-T-R-S-K-K-L-C-E-S-A-G-V-T-S-T-T-K-I-R-D-L-S-E-P-E-I-E-R-L-R-A-E-V-G-K-Y-V-V-E-G-D-L-R-R-E-I-G-I-A-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-L-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-K-A-I-R-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-T-M-E-A-K-A-I-L-R-T-A-R-I-S-P-Q-K-A-R-L-V-A-D-Q-V-R-G-L-S-A-E-R-A-V-N-L-L-K-F-S-D-K-K-A-A-H-L-I-K-K-V-V-E-S-A-I-A-N-A-E-N-N-Q-G-A-D-V-D-E-L-K-V-K-T-I-M-V-D-E-G-P-S-L-K-R-F-M-A-R-A-K-G-R-G-T-R-I-L-K-R-T-S-H-I-T-V-V-V-G-A-A-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-Y-L-D-V-A-D-N-S-G-A-K-E-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-H-I-G-D-I-I-K-V-T-V-K-D-A-I-P-R-G-K-V-K-K-G-E-V-Y-D-A-V-V-V-R-T-R-K-G-V-R-R-P-D-G-S-L-I-R-F-D-G-N-A-A-V-L-L-N-N-K-Q-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-S-E-K-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-S-M-I-H-R-D-I-K-R-A-K-L-A-K-K-F-A-G-K-R-D-A-L-K-K-I-L-S-S-Q-D-A-S-Y-E-E-K-I-D-A-S-T-K-L-Q-K-L-P-R-D-S-S-P-S-R-H-R-N-R-C-E-L-S-G-R-P-R-G-V-Y-R-K-F-G-L-G-R-N-M-L-R-K-A-T-M-N-G-D-V-P-G-L-R-K-A-S-W"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-T-T-F-T-A-K-S-E-T-V-Q-R-D-W-Y-L-V-D-A-A-G-K-T-L-G-R-L-S-T-E-L-A-R-R-L-R-G-K-H-K-P-V-Y-T-P-H-V-D-T-G-D-Y-L-V-V-I-N-A-E-K-I-V-V-T-G-N-K-L-K-D-K-K-Y-H-R-F-T-G-Y-I-G-N-L-K-T-E-S-L-E-Q-A-L-Q-R-H-P-E-R-V-I-E-I-A-V-K-G-M-L-P-K-G-P-L-G-R-T-M-Y-R-K-L-K-V-Y-S-G-A-E-H-P-H-A-A-Q-Q-P-Q-V-L-D-I"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-L-P-A-Q-H-K-L-N-S-S-M-Q-F-R-T-V-M-R-K-G-R-R-A-G-S-K-T-V-V-V-H-L-W-D-S-A-E-S-L-D-G-T-E-K-Q-G-E-V-A-S-F-G-G-P-R-F-G-L-V-V-S-K-A-V-G-N-A-V-V-R-H-R-T-S-R-R-L-R-H-I-C-A-S-I-A-E-K-S-P-E-L-L-S-P-T-H-H-V-V-I-R-A-L-A-G-A-G-N-A-T-S-A-E-L-E-R-D-I-R-Y-G-L-G-K-A-S-R-V-R-T-N-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-Q-Y-E-L-M-I-I-L-D-P-S-Q-D-E-R-T-V-A-P-S-L-D-K-F-L-E-V-V-R-K-D-K-G-D-V-V-K-V-D-V-W-G-K-R-R-L-A-Y-P-I-D-K-K-E-E-G-V-Y-A-V-V-D-L-K-C-E-S-A-T-V-L-E-L-D-R-V-L-N-L-N-D-G-V-L-R-T-K-V-L-R-L-D-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-I-L-T-A-A-V-E-N-L-G-V-A-G-D-I-V-E-V-K-N-G-Y-G-R-N-L-L-L-P-R-G-L-A-I-V-A-T-P-G-A-E-K-Q-I-E-G-I-K-R-A-Q-E-A-R-E-I-R-D-L-D-H-A-R-E-V-K-V-A-L-E-A-L-E-G-V-T-I-A-V-R-T-S-E-S-G-K-L-F-G-S-V-K-T-D-D-I-V-D-A-V-K-A-A-G-G-P-N-L-D-K-R-A-I-V-L-P-K-N-L-V-K-T-T-G-K-Y-Q-V-E-A-K-L-T-D-G-I-V-S-R-V-K-F-E-V-V-A-A"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-S-S-N-S-I-N-A-E-A-R-A-E-L-A-E-L-I-K-E-L-A-V-V-H-G-E-V-T-L-S-S-G-K-K-A-D-Y-Y-I-D-V-R-R-A-T-L-H-A-R-A-S-R-L-I-G-Q-L-L-R-E-A-T-A-D-W-D-Y-D-A-V-G-G-L-T-L-G-A-D-P-V-A-T-A-I-M-H-A-D-G-R-D-I-N-A-F-V-V-R-K-E-A-K-K-H-G-M-Q-R-R-I-E-G-P-D-L-T-G-K-K-V-L-V-V-E-D-T-T-T-T-G-N-S-P-L-T-A-V-A-A-L-R-E-A-G-I-E-V-V-G-V-A-T-V-V-D-R-A-T-G-A-D-E-V-I-A-A-E-G-L-P-Y-R-S-L-L-G-L-S-D-L-G-L-N"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-T-V-R-P-I-V-I-H-G-D-P-V-L-H-N-P-T-Q-L-V-T-E-D-V-S-E-L-Q-E-L-I-A-D-M-Y-E-T-M-D-V-A-N-G-V-G-L-A-A-N-Q-I-G-V-S-K-R-I-F-V-Y-D-C-P-D-D-E-G-V-M-H-K-G-C-F-I-N-P-V-L-E-T-S-E-I-P-E-T-M-P-A-D-D-G-S-D-E-E-G-C-L-S-V-P-G-E-G-F-P-T-G-R-A-H-W-A-K-V-T-G-L-N-E-K-G-E-E-V-S-V-E-A-E-G-F-L-A-R-C-F-Q-H-E-V-G-H-L-D-G-F-L-Y-T-D-V-L-I-G-R-W-K-R-M-A-K-K-A-I-K-A-N-G-W-T-E-P-G-L-T-W-M-P-G-E-D-E-D-P-F-G-H-D-A"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-F-L-Y-A-A-L-G-G-F-F-G-G-F-L-R-W-S-L-A-Q-L-F-P-G-K-R-A-T-L-A-A-N-T-L-A-C-L-A-G-G-F-F-V-S-L-D-L-P-H-L-Y-T-V-L-L-I-A-G-F-C-G-A-L-S-T-W-S-T-L-A-K-E-L-G-Q-L-L-N-E-K-K-W-W-P-M-L-G-Y-L-S-L-T-F-T-L-G-Y-S-A-V-F-L-G-M-R-L"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Q-K-L-I-Q-G-L-G-V-G-A-G-A-A-L-G-V-C-V-R-L-A-L-T-L-W-L-G-D-S-A-W-P-I-L-T-I-N-V-L-G-A-F-L-M-G-W-L-R-P-N-A-F-W-G-T-G-F-L-G-G-F-T-T-F-S-A-M-M-L-N-D-V-S-F-Y-F-F-T-A-V-G-C-I-L-A-W-L-A-G-D-R-L-A-R"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-S-P-S-A-P-L-A-T-P-D-V-E-L-D-V-H-T-L-S-S-E-N-L-P-W-L-C-I-V-W-D-D-P-V-N-L-M-S-Y-V-T-Y-V-F-Q-T-V-L-G-F-S-K-K-R-A-T-E-L-M-M-Q-V-H-T-E-G-K-A-V-V-S-S-G-E-K-D-K-V-E-G-D-V-K-K-L-H-T-A-G-L-W-A-T-M-Q-Q-A-G"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-S-I-G-T-D-L-V-H-I-S-A-F-A-E-Q-L-A-Q-P-G-S-S-F-M-E-V-F-S-A-G-E-R-R-K-A-N-E-R-Q-A-S-R-Y-A-E-H-L-A-G-R-W-A-A-K-E-S-F-I-K-A-W-S-Q-A-I-Y-G-Q-P-P-V-I-A-E-E-A-V-V-W-R-D-I-E-V-R-A-D-A-W-G-R-V-A-I-E-L-A-P-E-L-A-A-V-V-R-E-S-I-G-E-F-S-S-S-L-S-I-S-H-D-G-D-Y-A-V-A-T-C-V-L-T-I-Q"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-K-T-G-G-K-Q-Y-K-V-A-E-G-D-L-V-K-V-E-K-I-E-G-E-P-G-A-S-V-A-L-T-P-V-L-L-V-D-G-A-D-V-T-T-A-A-D-K-L-A-S-V-S-V-N-T-E-I-V-E-H-T-K-G-P-K-I-K-I-L-K-Y-K-N-K-T-G-Y-K-K-R-Q-G-H-R-Q-P-L-T-V-L-K-V-T-G-I-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-I-K-R-N-K-T-N-E-K-A-R-L-R-N-Q-A-V-R-S-A-V-R-T-E-I-R-K-F-N-A-A-I-E-A-G-D-K-D-A-A-Q-A-Q-L-R-T-A-S-R-A-L-D-K-A-V-T-K-G-V-F-H-I-N-N-A-A-N-K-K-S-N-M-A-T-A-F-N-K-L-G"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-I-E-V-F-N-E-S-G-Y-D-G-V-N-E-E-M-L-I-D-V-L-S-F-A-L-G-E-M-D-I-H-P-D-A-E-A-S-I-H-I-V-D-V-D-T-I-A-D-L-H-V-K-W-L-D-L-E-G-P-T-D-V-M-S-F-P-M-D-E-L-T-P-G-Y-S-R-P-D-G-A-T-P-G-P-A-M-L-G-D-I-V-L-C-P-E-F-A-A-K-Q-A-T-K-A-G-H-D-L-A-H-E-L-A-L-L-T-V-H-G-S-L-H-L-L-G-Y-D-H-V-D-P-A-E-E-R-E-M-F-A-L-Q-N-E-L-L-A-D-W-Y-D-N-V-E-A-R-G-V-T-Y-Q-P-K-P-S-G-A-G-A-F-P-T-A-A-D-R-L-E-L-D-E-K-M-E-A-D-D-S-G-F-G-G-V-E-S"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-T-E-Q-E-L-Q-I-G-K-V-V-K-S-H-G-I-R-G-E-V-V-V-E-L-S-T-D-D-P-D-I-R-F-A-I-G-E-V-L-N-G-K-Q-A-G-K-E-H-S-L-T-I-D-A-A-R-M-H-Q-G-R-L-L-V-K-F-A-E-V-P-D-R-T-A-A-D-S-L-R-G-T-R-F-F-A-A-P-L-E-D-E-D-D-E-D-G-F-Y-D-H-E-L-E-G-L-R-V-I-H-E-G-E-D-I-G-E-V-T-G-V-M-H-G-P-A-G-E-I-L-E-V-R-L-T-S-G-K-E-T-L-I-P-F-V-H-A-I-V-P-E-V-D-L-E-E-G-T-A-T-I-T-P-P-E-G-L-L-D-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-I-L-D-K-I-D-A-A-S-L-R-D-D-V-P-A-F-R-A-G-D-T-L-D-V-H-V-K-V-I-E-G-T-T-T-R-T-Q-L-F-K-G-V-V-I-R-R-Q-G-G-G-I-R-E-T-F-T-V-R-K-V-S-F-G-I-G-V-E-R-T-F-P-V-H-S-P-N-I-E-K-I-E-V-I-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-E-L-R-G-K-A-A-R-I-K-E-K-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-D-E-I-L-F-E-A-E-E-R-M-T-A-T-V-E-H-T-R-E-D-L-T-T-I-R-T-G-R-A-N-P-A-M-F-N-G-V-M-A-E-Y-Y-G-V-P-T-P-I-T-Q-M-S-G-I-T-V-P-E-P-R-M-L-L-I-K-P-Y-E-M-S-S-M-Q-V-I-E-N-A-I-R-N-S-D-L-G-V-N-P-T-N-D-G-Q-V-L-R-V-T-I-P-Q-L-T-E-E-R-R-K-D-M-V-K-L-A-K-G-K-G-E-D-G-K-I-A-I-R-N-I-R-R-K-G-M-D-Q-L-K-K-L-Q-K-D-G-D-A-G-E-D-E-V-Q-A-A-E-K-E-L-D-K-V-T-A-G-F-V-A-Q-V-D-E-V-V-A-R-K-E-K-E-L-M-E-V"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-F-P-T-T-E-I-L-S-A-L-I-E-P-L-A-A-S-H-K-F-D-L-E-G-L-K-V-T-K-A-G-P-K-S-A-V-A-I-K-V-D-S-D-S-R-P-D-L-D-Q-L-E-V-F-S-Q-E-I-G-E-L-F-D-A-A-E-Q-R-G-E-L-N-F-G-A-G-Y-T-L-E-V-S-T-P-G-V-D-N-P-L-T-L-P-R-H-W-R-R-N-R-G-R-L-V-A-L-D-Q-D-G-K-K-R-V-A-R-I-G-A-L-N-D-A-E-T-H-V-V-L-I-E-R-N-K-K-L-L-E-V-T-T-L-E-L-A-H-S-P-R-A-V-V-E-I-E-F-A-K-P-A-Q-D-E-T-A-L-A-E-S-T-F-D-E-A-T-A"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-D-N-A-R-A-A-R-M-A-K-R-I-Q-T-I-V-A-S-A-I-E-R-D-I-K-D-R-R-L-E-F-V-T-I-T-D-V-T-M-T-G-D-L-H-D-A-K-V-F-Y-T-V-R-G-A-S-I-E-E-E-P-D-L-E-A-A-A-E-A-L-H-R-A-R-G-Q-L-R-K-I-V-G-Q-Q-L-G-V-R-F-T-P-T-L-T-Y-S-I-D-T-V-P-E-A-S-A-H-M-E-A-L-L-D-R-A-R-K-R-D-E-E-L-A-K-L-R-E-G-A-A-P-A-G-D-A-D-P-Y-K-T-S-S-K-S-E-S-E-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-S-E-Q-K-K-S-I-L-S-E-F-G-L-H-E-T-D-T-G-S-P-E-A-Q-I-A-L-L-T-N-R-I-N-N-L-T-E-H-L-K-F-H-K-H-D-H-H-S-R-R-G-L-L-L-L-V-G-R-R-R-G-L-L-K-Y-L-A-D-N-N-V-D-R-Y-R-D-L-I-A-R-L-G-L-R-R"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-D-I-Q-A-E-K-I-E-K-L-R-K-A-L-D-N-F-E-R-A-H-A-R-G-E-S-D-F-F-D-H-E-K-E-E-K-K-A-N-V-R-R-R-A-L-L-L-L-N-Q-R-A-R-S-V-N-E-L-S-T-R-L-K-A-L-E-F-E-E-D-I-I-N-E-V-I-G-D-L-T-R-S-K-L-L-D-D-E-V-F-A-T-E-W-V-R-Q-R-A-A-R-R-G-K-S-S-R-A-L-D-R-E-L-Q-E-K-G-V-D-K-Q-T-R-A-A-A-L-E-Q-I-D-Q-A-D-E-R-D-T-A-R-A-V-A-V-K-K-A-R-S-E-T-K-I-P-Q-D-R-A-D-Y-D-K-A-L-R-R-V-V-G-A-L-A-R-R-G-F-P-A-G-M-S-M-D-L-A-R-E-A-L-D-A-R-I-E-D-L-K-N"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Y-C-P-F-C-Q-H-D-H-S-K-V-I-D-S-R-V-I-D-A-G-S-A-I-R-R-R-R-E-C-S-K-C-E-G-R-F-T-T-I-E-K-A-V-L-L-V-V-K-R-N-G-V-T-E-P-F-S-R-E-K-V-V-T-G-V-R-R-A-C-Q-G-R-D-V-S-D-D-A-L-K-R-L-A-Q-Q-V-E-E-T-V-R-S-N-G-S-S-Q-V-R-A-N-D-I-G-L-A-I-L-D-P-L-R-E-L-D-E-V-A-Y-L-R-F-A-S-V-Y-K-S-F-D-S-A-D-D-F-E-K-E-I-R-L-M-R-R-R-G-R-D"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-D-L-A-A-I-K-I-V-R-L-D-K-E-L-P-L-P-K-R-A-H-R-G-D-A-G-V-D-L-H-A-T-T-D-A-V-I-A-P-G-H-R-E-I-V-G-T-G-I-A-I-A-L-P-L-G-T-V-G-L-V-H-P-R-S-G-L-A-A-R-E-G-L-S-I-V-N-A-P-G-T-I-D-A-D-Y-R-G-E-I-K-V-C-L-I-N-L-D-P-E-K-P-I-M-I-T-R-G-D-R-I-A-Q-L-V-I-Q-K-V-E-L-V-D-F-E-E-V-E-E-L-D-D-T-V-R-G-D-Q-G-Y-G-S-T-G-K-T-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-K-V-S-A-D-T-P-G-H-D-D-P-G-P-G-R-R-L-G-L-D-V-G-T-V-R-I-G-V-A-A-S-D-R-D-A-K-L-A-M-P-V-E-T-V-P-R-E-T-G-F-K-G-P-D-L-A-D-I-D-R-L-V-A-I-V-E-E-Y-N-A-V-E-V-I-V-G-L-P-T-D-L-Q-G-N-G-S-A-S-V-K-H-A-K-E-I-A-F-R-V-R-R-R-L-T-N-A-G-K-N-I-P-V-R-L-G-D-E-R-L-T-T-V-V-A-T-Q-A-L-R-A-S-G-V-S-E-K-A-G-R-K-V-I-D-Q-A-A-A-V-E-I-L-Q-T-W-L-D-A-R-T-R-A-L-E-P-Q-S-T-D-T-Q-D-F-D-E-K-G-N-F-P-G"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-V-R-E-V-R-L-F-G-D-P-V-L-V-S-R-A-D-E-V-V-D-F-D-E-S-L-S-T-L-I-D-D-M-F-D-T-M-E-D-A-G-G-V-G-L-A-A-N-Q-V-G-V-L-R-R-V-F-V-F-D-T-S-H-Q-E-G-G-L-R-G-H-V-I-N-P-V-W-E-P-L-T-E-D-T-Q-T-G-K-E-G-C-L-S-I-P-D-V-S-A-E-T-T-R-Y-E-T-V-R-L-S-G-Q-D-R-D-G-N-P-V-G-F-V-A-N-G-L-L-A-R-C-I-Q-H-E-T-D-H-L-D-G-V-L-F-L-K-R-L-D-P-A-E-R-K-A-A-M-G-V-I-R-A-S-A-W-F-N-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-A-K-E-G-L-P-A-V-E-L-P-D-A-S-G-L-K-V-A-V-V-T-A-R-W-N-A-E-I-C-D-R-L-H-K-H-A-V-D-A-G-R-A-A-G-A-T-V-S-E-Y-R-V-I-G-A-L-E-L-P-V-V-V-Q-E-L-A-R-T-H-D-A-V-V-A-L-G-C-V-V-R-G-G-T-P-H-F-D-Y-V-C-D-S-V-T-E-G-L-T-R-I-A-L-D-T-S-T-P-I-G-N-G-V-L-T-T-N-T-E-E-Q-A-V-E-R-S-G-G-E-G-S-V-E-D-K-G-A-E-A-M-V-A-A-L-D-T-A-L-V-L-S-Q-I-R-A-T-E-G"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-S-L-G-P-W-E-I-G-I-I-V-L-L-I-I-V-L-F-G-A-K-K-L-P-D-A-A-R-S-I-G-R-S-M-R-I-F-K-S-E-V-K-E-M-N-K-D-G-D-T-P-E-Q-Q-Q-Q-P-Q-Q-Q-I-A-P-N-Q-I-E-A-P-Q-P-N-F-E-Q-H-Y-Q-G-Q-Q-V-Q-Q-P-Q-N-P-Q-T-P-D-Y-R-Q-N-Y-E-D-P-N-R-T-S"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-P-F-L-Q-I-S-L-L-S-I-G-V-A-A-D-A-F-A-C-S-V-V-R-G-T-A-I-Q-V-N-L-F-K-R-A-L-V-L-A-G-I-F-G-V-F-Q-A-A-M-P-L-I-G-W-F-I-G-R-F-F-A-G-I-T-F-I-A-E-I-D-H-W-I-A-F-A-L-L-G-I-V-G-T-K-M-I-W-D-A-F-Q-P-E-D-D-E-T-I-V-D-D-G-R-V-Q-F-R-P-A-I-I-L-G-L-A-T-S-I-D-A-L-A-V-G-M-G-L-A-F-V-E-V-S-I-L-K-V-A-L-S-M-G-S-I-T-F-A-L-S-L-A-G-A-W-I-G-H-H-G-G-G-K-F-G-K-W-A-T-I-L-G-G-I-I-L-I-G-I-G-A-N-I-V-Y-E-H-L-S-A"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-S-V-N-A-K-K-K-R-R-E-I-L-K-S-A-K-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-W-L-H-S-M-T-Y-S-Y-R-D-R-R-A-R-K-S-E-F-R-K-L-W-I-Q-R-I-N-A-A-A-R-M-N-G-I-T-Y-N-R-L-I-Q-G-L-R-L-A-E-I-E-V-D-R-K-I-L-A-D-L-A-V-N-D-F-A-T-F-S-A-I-C-E-A-A-K-A-A-L-P-E-D-V-N-A-P-K-A-A"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-V-R-Y-V-K-F-S-R-T-A-N-R-G-V-H-I-S-A-E-A-R-I-N-E-R-I-R-V-P-E-V-R-L-V-G-P-N-G-E-Q-V-G-I-V-R-I-E-D-A-R-K-L-A-F-D-A-D-L-D-L-V-E-V-A-P-N-A-K-P-P-V-C-K-I-M-D-Y-G-K-F-K-Y-E-A-A-Q-K-A-R-E-S-R-K-N-Q-Q-Q-T-V-V-K-E-Q-K-L-R-P-K-I-D-D-H-D-Y-E-T-K-K-N-N-V-I-R-F-L-E-K-G-S-K-V-K-V-T-I-M-F-R-G-R-E-Q-A-R-P-E-L-G-Y-R-L-L-E-R-L-A-N-D-V-V-D-F-G-I-V-E-T-R-A-K-Q-D-G-R-N-M-T-M-V-L-G-P-V-R-K-G-K-K"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-P-E-I-S-R-D-Q-V-A-H-L-A-K-L-S-R-L-A-L-T-E-E-E-L-E-Q-F-A-G-Q-I-D-D-I-V-G-Y-V-S-A-V-Q-N-V-D-A-A-G-V-E-P-M-S-H-P-H-S-I-A-T-T-M-R-E-D-V-V-H-K-T-L-D-A-A-A-A-L-D-Q-A-P-A-V-E-D-G-R-F-M-V-P-Q-I-L-G-E-G-D"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-S-S-V-G-W-G-E-I-F-L-L-V-V-V-G-L-V-V-I-G-P-E-R-L-P-R-L-I-Q-D-A-R-A-A-L-L-A-A-R-T-A-I-D-N-A-K-Q-S-L-D-S-D-F-G-S-E-F-D-E-I-R-K-P-L-T-Q-V-A-Q-Y-S-R-M-S-P-K-T-A-I-T-K-A-L-F-D-N-D-S-S-F-L-D-D-F-D-P-K-K-I-M-A-E-G-T-E-G-E-A-Q-R-N-K-Q-A-A-D-N-N-A-N-V-V-E-R-P-A-D-G-S-T-A-R-P-T-Q-N-D-P-K-D-G-P-N-Y-S-G-G-V-S-W-T-D-I-I"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-A-K-Y-Q-T-I-E-A-A-V-R-S-E-F-G-K-G-S-A-R-R-A-R-V-A-G-Q-I-P-A-V-V-Y-G-A-D-V-E-S-N-L-H-V-T-I-D-H-R-T-F-A-A-L-V-R-Q-E-G-V-N-A-V-L-E-L-D-I-E-G-Q-K-Q-L-T-M-I-K-H-I-D-Q-N-V-L-T-F-H-I-D-H-L-D-L-L-A-I-K-R-G-E-K-V-E-V-D-V-P-V-I-V-E-G-E-P-A-P-G-T-M-W-V-Q-D-A-D-T-I-K-V-E-A-D-V-L-S-I-P-E-E-F-T-V-S-I-E-G-L-E-L-G-A-Q-I-T-A-A-D-I-K-L-E-G-D-T-T-L-V-E-D-P-E-T-L-I-V-N-I-V-L-P-A-V-E-E-E-D-T-E-E-D-E-A-A-E-E-A-A-T-E"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-N-N-S-P-L-L-V-V-G-L-G-N-P-G-P-K-Y-V-G-T-R-H-N-I-G-F-E-V-A-E-E-L-V-S-R-S-F-G-S-F-S-V-H-K-R-S-N-T-D-I-A-Q-L-P-G-L-I-V-A-K-P-R-S-F-M-N-L-S-G-T-P-I-R-A-L-C-D-F-F-K-I-S-P-A-N-V-I-V-V-H-D-E-L-E-L-D-F-G-S-V-K-L-R-Q-G-G-G-D-H-G-H-N-G-L-K-S-T-S-K-S-L-G-T-K-D-Y-W-K-L-S-M-G-I-G-R-P-P-G-R-M-D-P-A-S-F-V-L-K-P-F-G-K-Q-E-L-A-D-I-P-I-M-A-A-D-A-A-D-L-V-E-K-H-L-Q-Q-G"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-N-E-K-R-K-E-I-V-A-R-Y-A-E-R-R-A-E-L-K-A-I-I-S-N-P-N-T-S-D-E-D-R-L-D-A-Q-F-E-L-N-S-Q-P-R-D-A-A-A-V-R-V-R-N-R-D-S-H-D-G-R-P-R-G-Y-L-R-K-F-G-L-S-R-V-R-M-R-E-M-A-H-R-G-E-L-P-G-V-R-K-S-S-W"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-K-K-K-V-D-E-N-N-S-V-L-A-T-N-R-K-A-R-H-D-Y-H-I-I-D-T-W-E-A-G-V-V-L-L-G-T-E-I-K-S-L-R-E-G-K-V-S-L-V-D-S-F-A-T-I-D-N-G-E-I-W-L-Q-H-L-H-I-P-Q-Y-S-M-G-S-W-T-N-H-T-P-K-R-T-R-K-L-L-L-H-R-N-E-I-D-S-L-M-G-K-V-R-D-G-N-R-T-L-V-P-L-K-L-Y-L-K-N-G-R-V-K-L-E-L-G-L-A-Q-G-K-Q-D-Y-D-K-R-Q-D-I-K-R-R-T-E-E-R-E-V-T-R-E-L-G-R-R-I-K-G-I-N-A"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-Q-I-V-L-A-S-Q-S-P-S-R-R-R-I-L-N-S-A-G-V-E-P-L-I-H-P-A-D-V-D-E-D-A-L-L-H-S-L-N-G-S-A-P-E-E-I-V-R-Q-L-A-L-A-K-A-Q-V-V-A-P-S-Y-P-G-D-V-V-I-G-G-D-S-M-L-L-I-D-A-T-L-Q-G-K-P-H-T-R-E-A-T-I-E-R-W-K-Q-Q-R-G-N-K-A-T-L-I-T-G-H-A-I-I-F-G-D-E-V-I-V-E-S-S-S-T-N-I-H-F-A-E-A-S-D-V-D-I-E-R-Y-A-D-S-G-E-P-L-E-C-A-G-A-F-T-L-E-A-L-G-G-W-F-I-D-S-I-E-G-D-P-S-S-V-I-G-L-S-L-P-V-V-R-R-A-L-Y-R-L-G-F-N-A-S-D-F-W-N-M"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-N-V-N-I-K-P-L-E-D-K-I-L-V-Q-I-N-E-A-E-T-T-T-A-S-G-L-V-I-P-D-S-A-K-E-K-P-Q-E-A-T-V-I-A-V-G-P-G-R-F-D-D-K-G-N-R-I-P-L-D-I-K-E-D-D-V-V-I-F-S-R-Y-G-G-T-E-I-K-F-G-G-V-E-Y-L-L-L-S-A-R-D-I-L-A-I-V-E-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-S-T-Y-H-P-K-S-G-D-I-T-R-K-W-Y-V-I-D-A-T-D-V-V-L-G-R-L-A-T-H-A-A-D-L-L-R-G-K-G-K-P-L-Y-A-P-N-V-D-C-G-D-H-V-I-V-I-N-A-D-K-V-A-V-T-S-N-K-R-E-R-E-M-R-Y-R-H-S-G-Y-P-G-G-L-K-S-M-T-L-G-R-S-L-D-L-H-P-E-R-T-I-E-D-S-I-V-G-M-M-P-H-N-K-L-T-A-A-S-A-K-K-L-H-V-F-S-G-S-E-H-P-Y-A-A-Q-K-P-E-A-Y-E-I-K-K-V-A-Q"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-P-P-K-A-R-T-N-A-R-R-T-G-R-R-V-V-K-K-N-V-A-N-G-N-A-Y-I-K-S-T-F-N-N-T-I-V-S-I-T-D-T-N-G-A-V-I-S-W-A-S-S-G-H-V-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-N-A-A-R-K-A-M-D-H-G-M-K-K-V-D-V-F-V-K-G-P-G-S-G-R-E-T-A-I-R-S-L-Q-A-A-G-L-E-I-G-S-I-S-D-V-T-P-Q-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-L-A-G-V-D-L-P-R-N-K-R-M-E-V-A-L-T-Y-I-Y-G-I-G-P-A-R-S-K-Q-L-L-E-E-T-G-I-S-P-D-L-R-T-D-N-L-T-D-E-Q-I-A-A-L-R-D-V-I-E-G-T-W-K-V-E-G-D-L-R-R-Q-V-Q-A-D-I-R-R-K-I-E-I-G-C-Y-Q-G-I-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-K-K-T-I-A-G-K-K-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-G-A-I-E-V-E-G-R-I-V-E-P-L-P-N-A-M-F-R-V-E-L-D-N-G-H-K-V-L-A-H-I-S-G-K-M-R-Q-H-Y-I-R-I-L-P-E-D-R-V-V-V-E-L-S-P-Y-D-L-T-R-G-R-I-V-Y-R-Y-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-N-T-E-N-K-Q-K-R-V-S-V-G-K-D-I-A-T-R-R-R-V-A-R-A-R-R-H-F-R-I-R-K-N-L-R-G-T-P-E-A-P-R-L-V-V-H-R-S-S-R-H-M-H-V-Q-I-I-D-D-V-A-G-H-T-L-A-A-A-S-S-I-E-A-E-V-R-A-T-E-G-D-K-K-A-K-G-A-K-V-G-Q-L-I-A-E-R-A-K-A-A-G-I-E-Q-V-V-F-D-R-A-G-Y-K-Y-H-G-R-V-A-A-L-A-D-A-A-R-E-G-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-E-P-I-T-I-P-S-G-V-E-T-K-I-D-G-Q-L-V-E-V-K-G-P-K-G-T-L-N-V-N-V-P-E-P-I-S-V-A-V-E-D-G-K-I-V-V-T-R-P-D-D-H-R-T-N-R-S-L-H-G-L-S-R-S-L-V-N-N-L-V-V-G-V-T-E-G-Y-T-I-K-M-E-I-F-G-V-G-Y-R-V-A-L-K-G-K-D-L-E-F-S-L-G-Y-S-H-P-V-L-I-E-A-S-E-G-I-T-F-A-V-D-G-N-T-K-L-S-V-S-G-I-D-K-Q-K-V-G-Q-V-A-A-V-I-R-R-L-R-K-D-D-P-Y-K-G-K-G-I-R-Y-E-G-E-Q-I-R-R-K-V-G-K-T-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-I-A-D-M-L-S-R-V-R-N-A-S-N-A-H-H-D-T-V-S-M-P-S-S-K-I-K-A-N-I-A-E-I-L-K-Q-E-G-Y-I-A-N-Y-T-V-E-D-A-K-V-G-K-T-L-S-L-E-L-K-Y-S-N-T-R-E-R-S-I-A-G-L-R-R-V-S-K-P-G-L-R-V-Y-A-K-S-T-N-L-P-Q-V-L-G-G-L-G-V-A-I-I-S-T-S-Q-G-L-L-T-D-R-Q-A-T-E-K-G-V-G-G-E-V-L-A-Y-V-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-E-N-Y-I-P-R-L-K-T-R-Y-Q-D-E-I-R-T-K-L-Q-G-E-F-E-F-E-N-V-M-Q-I-P-G-V-T-K-I-V-V-N-M-G-V-G-D-A-A-R-D-S-K-L-I-N-G-A-I-E-D-L-T-A-I-T-G-Q-K-P-Q-L-R-R-A-K-K-S-I-A-N-F-K-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-D-R-M-W-E-F-L-D-R-L-L-T-V-A-L-P-R-I-R-D-F-R-G-L-S-D-Q-Q-F-D-G-H-G-N-Y-T-F-G-L-T-E-Q-T-M-F-Y-E-I-D-V-D-K-I-D-R-P-R-G-M-D-I-T-V-V-T-T-A-V-T-D-D-E-G-R-S-L-L-R-E-L-G-F-P-F-K-G-E-D-G-N-R-Q-Q"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-V-H-K-G-D-M-V-L-V-I-S-G-P-D-K-G-A-K-G-Q-V-I-A-A-F-P-K-T-E-K-V-L-V-E-G-V-N-R-I-K-K-H-V-A-N-S-A-P-E-R-G-A-E-S-G-G-I-V-T-Q-E-A-P-I-H-V-S-N-V-M-V-I-D-S-D-G-N-P-T-R-V-G-Y-R-F-D-E-N-G-K-K-V-R-V-S-R-R-N-G-K-D-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-T-G-A-R-E-I-L-C-I-R-V-L-G-G-S-T-R-R-F-A-G-I-G-D-V-I-V-A-T-V-K-E-A-T-P-G-G-N-V-K-S-G-E-I-V-K-A-V-I-V-R-T-K-K-E-T-R-R-A-D-G-S-Y-I-S-F-D-E-N-A-A-V-I-I-K-N-D-N-E-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-K-K-F-M-K-I-V-S-L-A-P-E-V-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-A-N-V-N-N-Q-E-K-S-T-R-K-V-R-T-G-Y-V-V-S-D-K-M-Q-K-T-I-V-V-E-V-E-D-R-K-Q-H-A-L-Y-G-K-I-L-R-S-A-K-K-V-K-A-H-D-E-E-Q-I-A-G-I-G-D-L-V-R-I-E-E-T-R-P-L-S-K-D-K-N-Y-R-L-I-E-I-V-E-K-A-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-I-P-K-R-V-K-Y-R-R-Q-H-R-P-T-R-S-G-I-S-K-G-G-N-R-V-T-F-G-E-Y-G-I-Q-A-L-E-P-A-Y-I-T-N-R-Q-I-E-S-A-R-I-A-I-N-R-H-V-K-R-G-G-K-V-W-I-N-I-F-P-D-R-P-L-T-Q-K-P-L-G-V-R-M-G-S-G-K-G-P-V-E-K-W-V-A-N-I-K-P-G-R-I-L-F-E-M-S-Y-P-D-E-A-T-A-L-E-A-L-R-R-A-G-Q-K-L-P-C-K-V-R-I-V-K-R-E-D-Q-L"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-D-N-I-T-S-A-S-A-T-A-R-F-V-R-V-S-P-M-K-A-R-R-V-I-D-L-V-R-G-K-T-V-V-E-A-L-S-I-L-K-Y-A-P-Q-A-A-S-E-P-V-A-K-V-V-A-S-A-A-A-N-A-E-N-N-F-G-L-D-P-R-T-L-V-I-S-E-A-Y-A-N-E-G-P-T-M-K-R-F-Q-P-R-A-Q-G-R-A-F-Q-I-R-K-R-S-S-H-I-T-V-V-V-E-S-Q-K-E-G-A-N"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-A-T-I-A-N-P-R-D-I-I-I-A-P-V-V-S-E-K-S-Y-G-L-M-E-Q-N-V-Y-T-F-F-V-S-T-D-A-N-K-T-Q-I-K-I-A-I-E-E-I-F-G-V-K-V-A-S-V-N-T-V-N-R-A-G-K-R-K-R-S-R-T-G-F-G-T-R-K-A-T-K-R-A-Y-V-T-L-R-E-G-S-D-S-I-D-I-F-N-G-S-V-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-S-A-A-P-K-R-P-V-V-Q-D-P-V-Y-K-S-E-L-V-T-Q-L-V-N-K-I-L-I-G-G-K-K-S-T-A-E-R-I-V-Y-G-A-L-E-I-C-R-E-K-T-G-T-D-P-V-G-T-L-E-K-A-L-G-N-V-R-P-D-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-D-V-R-P-E-R-A-N-T-L-A-L-R-W-L-V-T-F-T-R-Q-R-R-E-N-T-M-I-E-R-L-A-N-E-L-L-D-A-A-N-G-L-G-A-S-V-K-R-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-Q-Q-L-V-R-K-G-R-H-D-K-S-A-K-V-A-T-A-A-L-K-G-S-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-I-E-V-S-A-Y-I-P-G-E-G-H-N-L-Q-E-H-S-M-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-K-I-V-R-G-A-L-D-T-Q-G-V-K-D-R-K-Q-A-R-S-R-Y-G-A-K-R-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-L-T-K-D-E-L-I-E-A-F-K-E-M-T-L-I-E-L-S-E-F-V-K-E-F-E-E-V-F-D-V-T-A-A-A-P-V-A-V-A-A-A-G-A-A-G-G-E-A-A-A-A-E-E-K-D-E-F-D-V-V-L-E-D-A-G-A-K-K-I-G-V-I-K-A-V-R-E-L-V-S-G-L-G-L-K-E-A-K-E-L-V-E-G-A-P-K-A-I-L-E-G-A-N-K-D-D-A-E-A-A-K-A-K-L-E-E-A-G-A-K-V-T-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-N-P-R-N-E-A-A-L-A-E-L-K-A-R-F-A-E-T-D-T-V-V-L-T-E-Y-R-G-L-T-V-A-Q-T-T-E-L-R-K-A-L-G-F-D-V-Q-Y-S-V-A-K-N-T-L-V-K-I-A-A-N-E-A-G-V-E-G-L-D-D-L-L-T-G-P-T-A-V-A-F-I-K-G-E-A-V-D-T-A-K-V-L-K-K-F-G-E-E-N-K-A-F-V-V-K-G-G-Y-M-D-G-N-A-L-T-A-E-Q-V-N-A-I-A-E-L-D-N-R-E-T-T-L-A-K-L-A-G-A-M-K-G-S-L-A-K-A-A-G-L-F-N-A-P-A-S-Q-V-A-R-L-A-V-A-L-Q-D-K-K-D-A"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-T-Q-P-D-M-S-Q-I-L-A-Q-A-Q-Q-M-Q-A-Q-L-Q-A-A-Q-Q-E-I-L-A-T-T-V-V-G-N-A-G-N-G-L-V-T-V-T-M-A-G-N-G-E-V-S-A-V-T-V-D-P-K-V-V-D-P-E-D-V-E-T-L-Q-D-L-L-L-G-A-F-K-D-A-H-N-K-V-A-N-V-A-E-E-K-M-G-P-L-S-Q-G-M-G-G-L-F"} +{"text": "### FUNCTION Involved in cell division ### SEQUENCE -M-P-K-A-R-V-T-K-N-E-T-A-P-V-S-S-N-P-S-A-N-R-T-P-V-K-I-N-S-A-G-T-P-M-W-Y-K-V-I-M-F-A-F-M-I-V-G-L-A-W-L-I-I-N-Y-L-V-G-P-Q-I-P-F-M-A-D-L-G-A-W-N-Y-G-I-G-F-G-L-M-I-I-G-L-L-M-T-M-G-W-R"} +{"text": "### FUNCTION Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, ie the esterification of glucose at the C6'' position with the carboxyl group of the C ### SEQUENCE -M-K-T-M-K-K-Y-I-K-T-A-F-F-C-S-M-Y-W-L-I-V-Q-L-N-I-A-N-L-G-T-R-I-P-D-K-Y-F-R-Q-K-Y-I-I-F-K-S-F-N-F-E-K-H-G-K-F-W-N-K-W-F-Y-V-R-K-W-K-H-K-I-L-D-G-H-Q-L-N-Q-N-I-Y-D-Q-R-H-L-M-T-I-N-T-D-E-I-E-K-M-I-I-E-T-K-R-A-E-L-I-H-W-I-S-I-L-P-V-I-I-F-N-K-G-P-R-L-V-K-Y-I-N-I-F-Y-A-M-I-A-N-V-P-I-I-I-V-Q-R-Y-N-R-P-R-L-T-Q-L-L-R-I-L-K-R-R-G-E-R-H-D"} +{"text": "### FUNCTION Activates transcription of virulence factors alpha- and beta hemolysin genes ### SEQUENCE -M-Y-V-E-N-S-Y-L-S-K-Q-L-C-F-L-F-Y-V-S-S-K-E-I-I-K-K-Y-T-N-Y-L-K-E-Y-D-L-T-Y-T-G-Y-I-V-L-M-A-I-E-N-D-E-K-L-N-I-K-K-L-G-E-R-V-F-L-D-S-G-T-L-T-P-L-L-K-K-L-E-K-K-D-Y-V-V-R-T-R-E-E-K-D-E-R-N-L-Q-I-S-L-T-E-Q-G-K-A-I-K-S-P-L-A-E-I-S-V-K-V-F-N-E-F-N-I-S-E-R-E-A-S-D-I-I-N-N-L-R-N-F-V-S-K-N-F-D-Y-S-D-K-K"} +{"text": "### FUNCTION May be involved in the biosynthesis of molybdopterin ### SEQUENCE -M-G-E-H-Q-N-V-K-L-N-R-T-V-K-A-A-V-L-T-V-S-D-T-R-D-F-D-T-D-K-G-G-Q-C-V-R-Q-L-L-Q-A-D-D-V-E-V-S-D-A-H-Y-T-I-V-K-D-E-K-V-A-I-T-T-Q-V-K-K-W-L-E-E-D-I-D-V-I-I-T-T-G-G-T-G-I-A-Q-R-D-V-T-I-E-A-V-K-P-L-L-T-K-E-I-E-G-F-G-E-L-F-R-Y-L-S-Y-V-E-D-V-G-T-R-A-L-L-S-R-A-V-A-G-T-V-N-N-K-L-I-F-S-I-P-G-S-T-G-A-V-K-L-A-L-E-K-L-I-K-P-E-L-N-H-L-I-H-E-L-T-K"} +{"text": "### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-T-E-F-T-H-I-N-Q-Q-G-H-A-K-M-V-D-V-S-D-K-Q-I-T-K-R-T-A-V-A-H-S-S-I-T-V-N-K-T-I-F-K-Q-I-S-N-N-T-N-T-K-G-N-V-L-N-T-A-Q-I-A-G-I-M-A-A-K-N-T-S-T-I-I-P-M-C-H-P-L-P-L-T-G-I-D-V-H-F-S-W-D-E-T-N-A-P-L-Y-T-L-N-I-Q-T-T-V-S-T-T-G-K-T-G-V-E-M-E-A-L-T-A-A-S-A-T-A-L-T-I-Y-D-M-T-K-A-V-D-K-G-M-I-I-G-E-T-Y-L-E-S-K-S-G-G-K-S-G-D-F-Q-R-Q-S-N-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-R-N-D-R-K-V-Y-V-G-K-V-V-S-D-K-M-D-K-T-I-T-V-L-V-E-T-Y-K-T-H-K-L-Y-G-K-R-V-K-Y-S-K-K-Y-K-T-H-D-E-N-N-S-A-K-L-G-D-I-V-K-I-Q-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-I-V-E-E-S-V-I-I"} +{"text": "### FUNCTION Involved in multidrug efflux ### SEQUENCE -M-I-V-N-Y-L-K-H-K-F-Y-N-L-L-T-T-M-V-V-L-F-I-F-V-L-S-G-A-I-F-L-T-F-L-G-F-G-L-Y-G-L-S-R-I-L-I-Y-F-R-L-G-D-F-T-Y-N-R-S-M-Y-D-N-L-L-Y-Y-G-S-Y-I-I-F-G-Y-F-I-I-F-A-V-E-H-L-M-D-Y-F-R-K-M-L-P-E-N-A-Y-F-R-G-A-T-F-H-L-I-S-Y-T-V-A-T-T-L-F-Y-F-I-I-H-L-N-Y-V-Y-I-N-I-D-F-W-V-I-M-V-I-I-G-F-L-Y-V-C-K-L-Q-F-Y-P-E-S-K-N-L-N-N-R-K"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-N-T-I-R-N-S-I-C-L-T-I-I-T-M-V-L-C-G-F-L-F-P-L-A-I-T-L-I-G-Q-I-F-F-Y-Q-Q-A-N-G-S-L-I-T-Y-D-N-R-I-V-G-S-K-L-I-G-Q-H-W-T-E-T-R-Y-F-H-G-R-P-S-A-V-D-Y-N-M-N-P-E-K-L-Y-K-N-G-V-S-S-G-G-S-N-E-S-N-G-N-T-E-L-I-A-R-M-K-H-H-V-K-F-G-N-S-N-V-T-I-D-A-A-T-S-S-G-S-G-L-D-P-H-I-T-V-E-N-A-L-K-Q-A-P-R-I-A-D-A-R-H-I-S-T-S-R-V-A-D-L-I-Q-H-R-K-Q-R-G-V-L-T-N-D-Y-V-N-V-L-E-L-N-I-A-L-D-K-M-K-D"} +{"text": "### FUNCTION Negative regulator of sigma-B activity Phosphorylates and inactivates its specific antagonist protein, RsbV Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme ### SEQUENCE -M-Q-S-K-E-D-F-I-E-M-R-V-P-A-S-A-E-Y-V-S-L-I-R-L-T-L-S-G-V-F-S-R-A-G-A-T-Y-D-D-I-E-D-A-K-I-A-V-S-E-A-V-T-N-A-V-K-H-A-Y-K-E-N-N-N-V-G-I-I-N-I-Y-F-E-I-L-E-D-K-I-K-I-V-I-S-D-K-G-D-S-F-D-Y-E-T-T-K-S-K-I-G-P-Y-D-K-N-E-N-I-D-F-L-R-E-G-G-L-G-L-F-L-I-E-S-L-M-D-E-V-T-V-Y-K-E-S-G-V-T-I-S-M-T-K-Y-I-K-K-E-Q-V-R-N-N-G-E-R-V-E-I-S"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-A-A-I-K-P-I-T-T-Y-K-G-K-I-V-P-L-F-N-D-N-I-D-T-D-Q-I-I-P-K-V-H-L-K-R-I-S-K-S-G-F-G-P-F-A-F-D-E-W-R-Y-L-P-D-G-S-D-N-P-D-F-N-P-N-K-P-Q-Y-K-G-A-S-I-L-I-T-G-D-N-F-G-C-G-S-S-R-E-H-A-A-W-A-L-K-D-Y-G-F-H-I-I-I-A-G-S-F-S-D-I-F-Y-M-N-C-T-K-N-A-M-L-P-I-V-L-E-K-N-A-R-E-H-L-A-K-Y-V-E-I-E-V-D-L-P-N-Q-T-V-S-S-P-D-K-R-F-H-F-E-I-D-E-T-W-K-N-K-L-V-N-G-L-D-D-I-A-I-T-L-Q-Y-E-S-L-I-E-K-Y-E-K-S-L"} +{"text": "### FUNCTION Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide This quorum sensing system is responsible for the regulation of the expression of virulence factor genes Involved in the proteolytic processing of AgrD, the precursor of AIP ### SEQUENCE -M-N-Y-F-D-N-K-I-D-Q-F-A-T-Y-L-Q-K-R-N-N-L-D-H-I-Q-F-L-Q-V-R-L-G-M-Q-V-L-A-K-N-I-G-K-L-I-V-M-Y-T-I-A-Y-I-L-N-I-F-I-F-T-L-I-T-N-I-S-F-Y-L-I-R-R-Y-A-H-G-A-H-A-P-S-S-F-W-C-Y-I-E-S-I-T-L-F-I-V-L-P-L-L-V-L-H-F-H-I-N-E-T-L-M-M-F-L-A-L-I-S-V-G-V-V-I-K-Y-A-P-A-A-T-K-K-K-P-I-P-A-R-L-V-K-Q-K-R-Y-F-S-I-I-I-S-T-I-L-F-I-I-T-L-F-V-K-E-P-Y-T-Q-F-I-Q-L-G-I-I-I-Q-A-I-T-L-L-P-I-Y-Y-S-K-E-D"} +{"text": "### FUNCTION Lyses erythrocytes and many other mammalian cells ### SEQUENCE -M-A-Q-D-I-I-S-T-I-S-D-L-V-K-W-I-I-D-T-V-N-K-F-T-K-K"} +{"text": "### FUNCTION Potent plasminogen activator that converts plasminogen into plasmin It forms a 11 complex with plasmin, which in turn activates other plasminogen molecules ### SEQUENCE -M-L-K-R-S-L-L-F-L-T-V-L-L-L-L-F-S-F-S-S-I-T-N-E-V-S-A-S-S-S-F-D-K-G-K-Y-K-K-G-D-D-A-S-Y-F-E-P-T-G-P-Y-L-M-V-N-V-T-G-V-D-G-K-G-N-E-L-L-S-P-H-Y-V-E-F-P-I-K-P-G-T-T-L-T-K-E-K-I-E-Y-Y-V-E-W-A-L-D-A-T-A-Y-K-E-F-R-V-V-E-L-D-T-S-A-K-I-E-V-T-Y-Y-D-K-N-K-K-K-E-E-T-K-S-F-P-I-T-E-K-G-F-V-V-P-D-L-S-E-H-I-K-N-P-G-F-N-L-I-T-K-V-V-I-E-K-K"} +{"text": "### FUNCTION Signal transduction protein, which is a major regulator of staphylococcal pathogenesis Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors Up-regulates the expression of most toxins and genes known to be necessary for biofilm formation ### SEQUENCE -M-K-K-L-Y-T-S-Y-G-T-Y-G-F-L-H-Q-I-K-I-N-N-P-T-H-Q-L-F-Q-F-S-A-S-D-T-S-V-I-F-E-E-T-D-G-E-T-V-L-K-S-P-T-K-Y-D-V-I-K-E-I-G-E-F-S-E-H-H-F-Y-C-A-I-F-I-P-S-T-E-D-H-A-Y-Q-L-E-K-K-L-I-S-V-D-D-N-F-R-N-F-G-G-F-K-S-Y-R-L-L-R-P-A-K-G-T-T-Y-K-I-Y-F-G-F-A-D-R-H-A-Y-E-D-F-K-Q-S-D-A-F-N-D-H-F-S-K-D-A-L-S-H-Y-F-G-S-S-G-Q-H-S-S-Y-F-E-R-Y-L-Y-P-I-K-E"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-S-I-I-L-V-M-I-G-G-G-F-G-A-I-T-R-S-A-I-T-D-Y-F-N-H-K-F-T-S-K-L-P-I-A-T-L-I-V-N-L-V-G-S-F-L-I-G-L-N-I-G-L-S-I-S-I-S-W-F-P-A-F-F-V-T-G-F-L-G-G-L-T-T-F-S-T-L-A-K-E-L-T-L-M-M-T-P-K-F-N-I-N-L-F-L-N-Y-S-L-L-Q-F-I-I-G-F-I-A-C-Y-I-G-Y-H-I"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-H-R-Q-F-L-S-S-R-C-Q-N-L-F-F-K-F-K-L-L-L-F-E-V-N-Q-M-Q-Y-V-Y-I-F-I-G-G-A-L-G-A-L-L-R-Y-L-I-S-F-L-N-T-D-G-G-F-P-I-G-T-L-I-A-N-L-T-G-A-F-V-M-G-L-L-T-A-L-T-I-A-F-F-S-N-H-P-T-L-K-K-A-I-T-T-G-F-L-G-A-L-T-T-F-S-T-F-Q-L-E-L-I-H-M-F-D-H-Q-Q-F-I-T-L-L-L-Y-A-V-T-S-Y-V-F-G-I-L-L-C-Y-V-G-I-K-L-G-G-G-L-S"} +{"text": "### FUNCTION Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival ### SEQUENCE -M-K-F-N-D-V-Y-N-K-H-H-K-I-I-H-H-L-L-K-K-Y-N-I-S-Y-N-Y-D-E-Y-Y-Q-L-L-L-I-K-M-W-Q-L-S-Q-I-Y-K-P-S-S-K-Q-S-L-S-S-F-L-F-T-R-L-N-F-Y-L-I-D-L-F-R-Q-Q-N-Q-L-K-D-V-I-L-C-E-N-N-S-P-T-L-T-E-Q-P-T-Y-F-N-E-H-D-L-R-L-Q-D-I-F-K-L-L-N-Q-R-E-R-L-W-L-K-L-Y-L-E-G-Y-K-Q-F-E-I-A-E-I-M-S-L-S-L-S-T-I-K-L-I-K-M-S-V-K-R-K-C-Q-H-N-F-N"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-K-V-N-P-N-N-I-E-L-I-I-S-A-V-K-E-E-Q-Y-P-K-T-E-L-S-E-V-A-L-S-G-R-S-N-V-G-K-S-T-F-I-N-S-M-I-G-R-K-N-M-A-R-T-S-Q-Q-P-G-K-T-Q-T-L-N-F-Y-N-I-D-E-Q-L-I-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-T-Q-R-E-K-F-G-K-M-I-E-E-Y-I-T-K-R-E-N-L-Q-L-V-I-Q-L-V-D-L-R-H-D-P-T-Q-D-D-I-L-M-Y-N-Y-L-K-H-F-D-I-P-T-L-V-I-C-T-K-E-D-K-I-P-K-G-K-V-Q-K-H-I-K-N-I-K-T-Q-L-D-M-D-P-D-D-T-I-V-S-Y-S-S-I-Q-N-N-K-Q-Q-Q-I-W-N-L-I-E-P-Y-I-S"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-F-T-I-D-F-S-D-H-T-G-L-V-K-D-A-W-Y-K-Q-I-E-D-L-L-E-F-A-K-K-E-E-H-I-E-D-D-A-E-L-S-V-T-F-V-D-K-Q-E-I-Q-E-I-N-R-T-Y-R-D-K-D-K-V-T-D-V-I-S-F-A-L-E-E-D-E-P-E-I-D-F-S-G-L-D-I-P-R-V-L-G-D-I-I-I-C-T-D-V-A-Q-E-Q-A-N-N-Y-G-H-S-F-E-R-E-L-G-F-L-A-L-H-G-F-L-H-L-L-G-Y-D-H-M-T-E-A-D-E-K-E-M-F-G-R-Q-D-T-I-L-N-A-Y-G-L-T-R-G"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-D-N-H-G-I-L-E-S-L-L-F-T-A-G-D-E-G-L-D-E-K-Q-L-L-E-I-L-D-M-S-K-N-Q-L-V-E-L-I-E-N-Y-S-S-H-G-L-M-I-Q-R-F-G-T-T-Y-V-L-T-T-K-K-E-A-A-T-Y-I-E-Q-L-I-E-Q-K-S-Q-M-K-L-S-Q-A-A-M-E-V-L-S-I-I-A-Y-N-Q-P-L-S-R-S-D-I-E-L-I-R-S-I-N-S-D-G-A-V-K-T-L-I-A-K-G-L-V-E-A-K-V-V-N-E-Q-R-S-Q-Q-L-I-T-T-D-L-F-L-N-V-F-G-I-S-N-I-E-D-L-P-T-T-E-E-D-D-E-E-M-D-A-F-F-S-N-L-V-N-Q-K-G-E-N-N-D"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-K-I-T-E-Q-V-E-V-I-V-K-P-I-M-E-D-L-N-F-E-L-V-D-V-E-Y-V-K-E-G-R-D-H-F-L-R-I-S-I-D-K-E-G-G-V-D-L-N-D-C-T-L-A-S-E-K-I-S-E-A-M-D-A-N-D-P-I-P-E-M-Y-Y-L-D-V-A-S-P-G-A-E-R-P-I-K-K-E-Q-D-F-Q-N-A-I-T-K-P-V-F-V-S-L-Y-V-P-I-E-G-E-K-E-W-L-G-I-L-Q-E-V-N-N-E-T-I-V-V-Q-V-K-I-K-A-R-T-K-D-I-E-I-P-R-D-K-I-A-K-A-R-H-A-V-M-I"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-T-N-H-K-L-I-E-A-V-T-K-S-Q-L-R-T-D-L-P-S-F-R-P-G-D-T-L-R-V-H-V-R-I-I-E-G-T-R-E-R-I-Q-V-F-E-G-V-V-I-K-R-R-G-G-G-V-S-E-T-F-T-V-R-K-I-S-S-G-V-G-V-E-R-T-F-P-L-H-T-P-K-I-E-K-I-E-V-K-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-S-L-R-G-K-A-A-R-I-Q-E-I-R"} +{"text": "### FUNCTION Extracellular fibrinogen-binding protein that plays an important role in virulence By interacting with the alpha chain of fibrinogen and its derivative fibrin, enhances a non-functional interaction between fibrinogen and platelets and is responsible for repression of fibrinogen-dependent platelet aggregation In addition, assembles a fibrinogen protective shield around the bacteria which results in impaired phagocytic clearance by the host Mechanistically, interacts with host complement C3b deposited on the surface of the bacterium via its C-terminal and then recruits fibrinogen via its N-terminal ### SEQUENCE -M-K-N-K-L-I-A-K-S-L-L-T-I-A-A-I-G-I-T-T-T-T-I-A-S-T-A-D-A-S-E-G-Y-G-P-R-E-K-K-P-V-S-I-N-H-N-I-V-E-Y-N-D-G-T-F-K-Y-Q-S-R-P-K-F-N-S-T-P-K-Y-I-K-F-K-H-D-Y-N-I-L-E-F-N-D-G-T-F-E-Y-G-A-R-P-Q-F-N-K-P-A-A-K-T-D-A-T-I-K-K-E-Q-K-L-I-Q-A-Q-N-L-V-R-E-F-E-K-T-H-T-V-S-A-H-R-K-A-Q-K-A-V-N-L-V-S-F-E-Y-K-V-K-K-M-V-L-Q-E-R-I-D-N-V-L-K-Q-G-L-V-K"} +{"text": "### FUNCTION May be involved in countering the first line of host defense mechanisms Impairs the leukocyte response to FPRL1 agonists by binding directly to host FPRL1 ### SEQUENCE -M-K-K-N-I-T-K-V-I-I-A-S-T-V-I-A-T-G-L-L-T-Q-T-N-D-A-K-A-F-F-S-Y-E-W-K-G-L-E-I-A-K-N-L-A-D-Q-A-K-K-D-D-E-R-A-D-K-L-I-K-E-A-D-E-K-N-E-H-Y-K-G-K-T-V-E-D-L-Y-V-I-A-K-K-M-G-K-G-N-T-I-A-V-V-K-I-K-D-G-G-K-N-G-Y-Y-T-F-D-I-T-R-P-L-E-E-H-R-K-N-I-P-V-V-K-N-G-E-I-D-S-I-T-W-Y"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-A-V-F-K-V-F-Y-Q-H-N-R-D-E-V-I-V-R-E-N-T-Q-S-L-Y-V-E-A-Q-T-E-E-Q-V-R-R-Y-L-K-D-R-N-F-N-I-E-F-I-T-K-L-E-G-A-H-L-D-Y-E-K-E-N-S-E-H-F-N-V-E-I-A-K"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-V-P-N-E-L-K-Y-S-K-E-H-E-W-V-K-V-E-G-N-V-A-T-I-G-I-T-E-Y-A-Q-S-E-L-G-D-I-V-F-V-E-L-P-E-T-D-D-E-I-N-E-G-D-T-F-G-S-V-E-S-V-K-T-V-S-E-L-Y-A-P-I-S-G-K-V-V-E-V-N-E-E-L-E-D-S-P-E-F-V-N-E-S-P-Y-E-K-A-W-M-V-K-V-E-I-S-D-E-S-Q-I-E-A-L-L-T-A-E-K-Y-S-E-M-I-G-E"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-K-S-P-G-T-L-A-E-N-R-K-A-R-H-D-Y-N-I-E-D-T-I-E-A-G-I-V-L-Q-G-T-E-I-K-S-I-R-R-G-S-A-N-L-K-D-S-Y-A-Q-V-K-N-G-E-M-Y-L-N-N-M-H-I-A-P-Y-E-E-G-N-R-F-N-H-D-P-L-R-S-R-K-L-L-L-H-K-R-E-I-I-K-L-G-D-Q-T-R-E-I-G-Y-S-I-V-P-L-K-L-Y-L-K-H-G-H-C-K-V-L-L-G-V-A-R-G-K-K-K-Y-D-K-R-Q-A-L-K-E-K-A-V-K-R-D-V-A-R-D-M-K-A-R-Y"} +{"text": "### FUNCTION Dephosphorylates the 5' and 2'-phosphates of deoxyribonucleotides ### SEQUENCE -M-T-R-K-S-I-A-I-D-M-D-E-V-L-A-D-T-L-G-E-I-I-D-A-V-N-F-R-A-D-L-G-I-K-M-E-A-L-N-G-Q-K-L-K-H-V-I-P-E-H-D-G-L-I-T-E-V-L-R-E-P-G-F-F-R-H-L-K-V-M-P-Y-A-Q-E-V-V-K-K-L-T-E-H-Y-D-V-Y-I-A-T-A-A-M-D-V-P-T-S-F-S-D-K-Y-E-W-L-L-E-F-F-P-F-L-D-P-Q-H-F-V-F-C-G-R-K-N-I-V-K-A-D-Y-L-I-D-D-N-P-R-Q-L-E-I-F-T-G-T-P-I-M-F-T-A-V-H-N-I-N-D-D-R-F-E-R-V-N-S-W-K-D-V-E-Q-Y-F-L-D-N-I-E-K"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-S-K-L-I-D-S-F-M-K-L-P-G-I-G-P-K-T-A-Q-R-L-A-F-H-T-L-D-M-K-E-D-D-V-V-Q-F-A-K-A-L-V-D-V-K-R-E-L-T-Y-C-S-V-C-G-H-I-T-E-N-D-P-C-Y-I-C-E-D-K-Q-R-D-R-S-V-I-C-V-V-E-D-D-K-D-V-I-A-M-E-K-M-R-E-Y-K-G-L-Y-H-V-L-H-G-S-I-S-P-M-D-G-I-G-P-E-D-I-N-I-P-S-L-I-E-R-L-K-N-D-E-V-S-E-L-I-L-A-M-N-P-N-L-E-G-E-S-T-A-M-Y-I-S-R-L-V-K-P-I-G-I-K-V-T-R-L-A-Q-G-L-S-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-I-A-G-R-T-E-M"} +{"text": "### FUNCTION Virulence factor that is important for the establishment of infection in the host EsxB is required for EsxA synthesis as well as secretion ### SEQUENCE -M-G-G-Y-K-G-I-K-A-D-G-G-K-V-D-Q-A-K-Q-L-A-A-K-T-A-K-D-I-E-A-C-Q-K-Q-T-Q-Q-L-A-E-Y-I-E-G-S-D-W-E-G-Q-F-A-N-K-V-K-D-V-L-L-I-M-A-K-F-Q-E-E-L-V-Q-P-I-A-D-H-Q-K-A-I-D-N-L-S-Q-N-L-A-K-Y-D-T-L-S-I-K-Q-G-L-D-R-V-N-P"} +{"text": "### FUNCTION Implements its pathogenic function during infection ### SEQUENCE -M-N-F-N-D-I-E-T-M-V-K-S-K-F-K-D-I-K-K-H-A-E-E-I-A-H-E-I-E-V-R-S-G-Y-L-R-K-A-E-Q-Y-K-R-L-E-F-N-L-S-F-A-L-D-D-I-E-S-T-A-K-D-V-Q-T-A-K-T-S-A-N-K-D-S-V-T-V-K-G-K-A-P-N-T-L-Y-I-E-K-R-N-L-M-K-Q-K-L-E-M-L-G-E-D-I-D-K-N-K-E-S-L-Q-K-A-K-E-I-A-G-E-K-A-S-E-Y-F-N-K-A-M-N"} +{"text": "### FUNCTION Component of the ESAT-6 secretion system Required for the secretion of EsxA and EsxB ### SEQUENCE -M-L-M-N-S-V-I-A-L-T-F-L-T-A-S-S-N-N-G-G-L-N-I-D-V-Q-Q-E-E-E-K-R-I-N-N-D-L-N-Q-Y-D-T-T-L-F-N-K-D-S-K-A-V-N-D-A-I-A-K-Q-K-K-E-R-Q-Q-Q-I-K-N-D-M-F-Q-N-Q-A-S-H-S-T-R-L-N-E-T-K-K-V-L-F-S-K-S-N-L-E-K-T-S-E-S-D-K-S-P-Y-I-Q-N-K-Q-E-K-K-I-F-P-Y-I-L-M-S-V-G-A-F-L-T-L-G-F-V-I-F-S-I-H-K-G-R-R-T-K-N-E-S-A-R-K-S-N-I"} +{"text": "### FUNCTION Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB The LrgAB and CidAB proteins may affect the proton motive force of the membrane May be involved in programmed cell death , possibly triggering PCD in response to antibiotics and environmental stresses ### SEQUENCE -M-K-Q-Q-K-D-A-S-K-P-A-H-F-F-H-Q-V-I-V-I-A-L-V-L-F-V-S-K-I-I-E-S-F-M-P-I-P-M-P-G-S-V-I-G-L-V-L-L-F-V-L-L-C-T-G-A-V-K-L-G-E-V-E-K-V-G-T-T-L-T-N-N-I-G-L-L-F-V-P-A-G-I-S-V-V-N-S-L-G-V-I-S-Q-A-P-F-L-I-I-G-L-I-I-V-S-T-I-L-L-L-I-C-T-G-Y-V-T-Q-I-I-M-K-V-T-S-R-S-K-G-D-K-V-T-K-K-I-K-I-E-E-A-Q-A-H-D"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-T-I-L-A-V-G-K-L-K-E-K-Y-W-K-Q-A-I-A-E-Y-E-K-R-L-G-P-Y-T-K-I-D-I-I-E-V-T-D-E-K-A-P-E-N-M-S-D-K-E-I-E-Q-V-K-E-K-E-G-Q-R-I-L-A-K-I-K-P-Q-S-T-V-I-T-L-E-I-Q-G-K-M-L-S-S-E-G-L-A-Q-E-L-N-Q-R-M-T-Q-G-Q-S-D-F-V-F-V-I-G-G-S-N-G-L-H-K-D-V-L-Q-R-S-N-Y-A-L-S-F-S-K-M-T-F-P-H-Q-M-M-R-V-V-L-I-E-Q-V-Y-R-A-F-K-I-M-R-G-E-A-Y-H-K"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-V-K-L-I-C-V-G-K-L-K-E-R-Y-L-K-D-G-I-S-E-Y-Q-K-R-L-S-R-F-C-Q-F-E-M-I-E-L-T-D-E-R-T-P-D-K-A-N-F-A-D-N-Q-L-I-M-S-K-E-A-Q-R-I-H-K-K-I-G-E-R-D-F-V-I-A-L-A-I-E-G-K-Q-F-P-S-E-T-F-S-E-L-I-S-G-V-T-V-K-G-Y-S-T-I-T-F-I-I-G-G-S-L-G-L-D-S-I-I-K-K-R-A-D-M-L-M-S-F-G-L-L-T-L-P-H-Q-L-M-R-L-V-L-T-E-Q-I-Y-R-A-F-M-I-T-K-G-S-P-Y-H-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-A-D-V-K-G-K-G-K-K-G-E-I-K-E-V-P-T-G-Y-A-Q-N-F-L-I-K-K-N-L-A-K-E-A-T-S-Q-S-I-G-E-L-K-G-K-Q-K-A-E-E-K-A-Q-A-E-I-L-A-E-A-Q-A-V-K-A-V-L-D-E-D-K-T-R-V-Q-F-Q-E-K-V-G-P-D-G-R-T-F-G-S-I-T-A-K-K-I-S-E-E-L-Q-K-Q-F-G-V-K-V-D-K-R-H-I-V-L-D-H-P-I-R-A-I-G-L-I-E-V-P-V-K-L-H-K-E-L-T-A-E-I-K-L-A-I-T-E-A"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-D-Y-I-K-G-Q-L-T-K-I-T-A-K-Y-I-V-V-E-A-N-G-L-G-Y-M-I-N-V-A-N-P-Y-S-F-T-D-S-V-N-Q-L-V-T-I-Y-L-H-Q-V-I-R-E-D-A-H-L-L-F-G-F-H-T-K-D-E-K-D-V-F-L-K-L-I-S-V-S-G-I-G-P-T-T-A-L-A-I-V-A-V-D-D-N-E-G-L-V-N-A-I-D-N-S-D-I-K-Y-L-M-K-F-P-K-I-G-K-K-T-A-Q-Q-M-V-L-D-L-A-G-K-F-V-E-A-P-Q-E-T-G-N-T-K-A-R-S-N-K-A-G-N-T-Q-L-D-E-A-I-E-A-L-L-A-L-G-Y-K-A-T-E-L-K-K-I-R-A-F-F-E-G-T-S-E-T-A-E-Q-Y-I-K-S-A-L-K-L-L-M-K-G"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-K-L-D-V-F-A-G-Q-E-K-S-E-L-S-M-I-E-V-A-R-A-I-L-E-E-R-G-R-D-N-E-M-Y-F-S-D-L-V-N-E-I-Q-N-Y-L-G-K-S-D-A-G-I-R-H-A-L-P-F-F-Y-T-D-L-N-T-D-G-S-F-I-P-L-G-E-N-K-W-G-L-R-S-W-Y-A-I-D-E-I-D-E-E-I-I-T-L-E-E-D-E-D-G-A-Q-K-R-K-K-K-R-V-N-A-F-M-D-G-D-E-D-A-I-D-Y-R-D-D-D-P-E-D-E-D-F-T-E-E-S-A-E-V-E-Y-D-E-D-D-P-D-D-E-K-S-E-V-E-S-Y-D-S-E-L-N-E-I-I-P-E-D-D-F-E-E-V-D-I-N-E-E-D-E-E-D-E-E-D-E-E-P-V-L"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-N-V-V-L-V-G-R-M-T-K-D-A-E-L-R-Y-T-P-S-Q-V-A-V-A-T-F-T-L-A-V-N-R-T-F-K-S-Q-N-G-E-R-E-A-D-F-I-N-C-V-I-W-R-Q-P-A-E-N-L-A-N-W-A-K-K-G-A-L-I-G-I-T-G-R-I-Q-T-R-N-Y-E-N-Q-Q-G-Q-R-V-Y-V-T-E-V-V-A-D-N-F-Q-M-L-E-S-R-A-T-R-E-G-G-S-T-G-S-F-N-G-G-F-N-N-N-T-S-S-S-N-S-Y-S-A-P-A-Q-Q-T-P-N-F-G-R-D-D-S-P-F-G-N-S-N-P-M-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-K-I-S-E-E-E-V-R-H-V-A-K-L-S-K-L-S-F-S-E-S-E-T-T-A-F-A-T-T-L-S-K-I-V-D-M-V-E-L-L-N-E-V-D-T-E-G-V-A-I-T-T-T-M-A-D-K-K-N-V-M-R-Q-D-V-A-E-E-G-T-D-R-A-L-L-F-K-N-V-P-E-K-E-N-H-F-I-K-V-P-A-I-L-Y-D-G-G-D-A"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-N-H-R-I-D-R-V-G-M-E-I-K-R-E-V-N-D-I-L-Q-K-K-V-R-D-P-R-V-Q-G-V-T-I-T-E-V-Q-M-Q-G-D-L-S-L-A-K-V-Y-Y-T-I-M-S-D-L-A-S-D-N-Q-K-A-Q-T-G-L-E-K-A-T-G-T-I-K-R-E-L-G-K-Q-L-T-M-Y-K-I-P-D-L-V-F-E-K-D-N-S-I-A-Y-G-N-K-I-D-Q-L-L-R-E-L-D-N-K-S"} +{"text": "### FUNCTION Transfers 2- of the citrate lyase to yield holo-acyl carrier protein ### SEQUENCE -M-C-K-D-T-Y-F-S-G-E-A-I-Q-L-S-D-M-L-R-A-R-E-E-R-A-L-R-Q-L-H-L-L-K-E-Y-P-E-G-S-L-L-S-V-T-M-N-I-P-G-P-I-K-T-S-P-K-L-L-E-A-F-D-I-V-I-K-A-I-Q-T-A-L-A-D-D-K-I-C-Y-Q-L-R-L-L-P-T-T-G-Y-E-Y-Y-L-I-T-S-L-P-S-Q-D-L-K-L-K-M-I-A-L-E-T-D-L-P-I-G-R-L-M-D-L-D-V-L-V-L-S-N-G-R-P-S-P-I-S-R-T-T-L-G-A-P-P-R-Q-C-F-I-C-S-K-E-A-K-V-C-G-R-L-R-K-H-S-V-E-E-M-Q-T-A-I-S-K-L-L-H-S-F-F-N-K-D-N-Q-S-S-S-S-D-K-T-G"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-D-I-K-Q-T-A-V-A-G-S-L-E-S-S-D-L-M-I-T-V-S-P-N-D-E-Q-T-I-T-I-T-L-D-S-S-V-E-K-Q-F-G-N-H-I-R-Q-L-I-H-Q-T-L-V-N-L-K-V-T-A-A-K-V-E-A-V-D-K-G-A-L-D-C-T-I-Q-A-R-T-I-A-A-V-H-R-A-A-G-V-D-Q-Y-D-W-K-E-I-D-S-W-N-V"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-E-A-I-I-A-K-K-A-E-Q-V-E-L-I-A-E-K-M-K-A-A-A-S-I-V-V-V-D-S-R-G-L-T-V-D-Q-D-T-V-L-R-R-S-L-R-E-S-G-V-E-F-K-V-I-K-N-S-I-L-T-R-A-A-E-K-A-G-L-D-E-L-K-D-V-F-V-G-P-S-A-V-A-F-S-N-E-D-V-I-A-P-A-K-V-I-N-D-F-T-K-T-A-D-A-L-E-I-K-G-G-A-I-E-G-A-V-S-S-K-E-E-I-Q-A-L-A-T-L-P-N-R-Q-G-M-L-S-M-L-L-S-V-L-Q-A-P-V-R-N-V-A-Y-A-V-K-A-V-A-E-N-K-E-G-A-A"} +{"text": "### FUNCTION Required for accurate and efficient protein synthesis under certain stress conditions May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes Back-translocation proceeds from a post-translocation ### SEQUENCE -M-K-Q-T-L-D-Y-I-D-D-N-R-V-N-V-I-Y-Q-I-P-L-A-E-I-V-F-D-F-F-D-K-L-K-S-S-T-R-G-Y-A-S-F-D-Y-D-M-S-E-Y-R-R-S-Q-L-V-K-M-D-I-L-L-N-G-D-K-V-D-A-L-S-F-I-V-H-K-E-F-A-Y-E-R-G-K-I-I-V-E-K-L-K-K-I-I-P-R-Q-Q-F-E-V-P-I-Q-A-A-I-G-Q-K-I-V-A-R-S-D-I-K-A-L-R-K-N-V-L-A-K-C-Y-G-G-D-V-S-R-K-R-K-L-L-E-K-Q-K-A-G-K-K-R-M-K-A-I-G-S-V-E-V-P-Q-E-A-F-L-S-V-L-S-M-D-E-D-A-K-K"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-A-E-E-Q-V-L-N-T-H-N-A-S-I-L-L-S-A-A-N-K-S-H-Y-P-Q-D-D-L-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-I-L-G-R-K-N-L-A-R-T-S-S-K-P-G-K-T-Q-L-L-N-F-F-N-I-D-D-K-L-R-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-S-E-R-A-E-W-G-K-M-I-E-E-Y-L-T-S-R-D-N-L-R-A-V-V-S-L-V-D-L-R-H-A-P-S-K-E-D-I-Q-M-Y-D-F-L-K-Y-Y-D-I-P-V-I-V-V-A-T-K-A-D-K-I-P-R-G-K-W-N-K-H-E-S-V-V-K-K-A-L-N-F-D-K-S-D-T-F-I-V-F-S-S-V-E-R-I-G-I-D-D-S-W-D-A-I-L-E-Q-V"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-Y-F-N-V-G-K-I-V-N-T-Q-G-L-Q-G-E-M-R-V-L-S-V-S-D-F-A-E-E-R-F-K-K-G-S-Q-L-A-L-F-D-D-K-D-Q-F-V-Q-E-V-T-I-V-S-H-R-K-Q-K-H-F-D-I-I-K-F-K-D-M-Y-H-I-N-A-I-E-K-Y-K-G-Y-T-L-K-V-S-K-A-N-Q-G-D-L-Q-E-G-E-F-Y-Y-H-Q-I-I-G-M-A-V-Y-E-K-D-R-L-I-G-Y-V-K-E-I-L-Q-P-G-A-N-D-V-W-V-V-K-R-Q-G-K-R-D-L-L-L-P-Y-I-P-P-V-V-L-S-V-D-V-P-N-K-R-V-D-V-E-L-M-E-G-L-D-D-E-D"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-T-K-K-E-Q-A-L-I-E-Q-Y-A-K-S-L-V-E-V-A-S-E-H-H-S-L-D-A-L-Q-A-D-V-L-A-I-L-E-T-F-V-T-T-N-L-D-Q-S-L-S-S-L-A-V-P-H-A-E-K-I-K-L-L-T-L-L-K-G-N-N-S-V-Y-M-N-N-F-L-N-L-I-L-Q-N-E-R-E-A-Y-L-Y-Q-M-L-Q-T-V-L-N-E-I-A-I-V-S-N-Q-Y-D-V-T-V-T-S-S-L-P-L-T-E-E-Q-K-S-R-V-R-A-V-V-A-K-K-F-A-V-T-A-G-R-L-I-E-K-V-D-P-S-L-I-G-G-F-I-I-S-V-N-N-K-V-I-D-T-S-I-R-R-Q-L-Q-A-F-K-M-N-L-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-I-T-F-G-E-L-V-G-N-F-I-L-V-T-G-S-V-I-V-L-L-L-L-I-K-K-F-A-W-G-A-I-E-S-I-L-Q-T-R-S-Q-Q-I-S-R-D-I-D-Q-A-E-Q-S-R-L-S-A-Q-Q-L-E-T-K-S-Q-A-N-L-D-A-S-R-S-Q-A-S-K-I-I-S-D-A-K-E-I-G-Q-L-Q-G-D-K-L-V-A-E-A-T-D-E-A-K-R-L-K-E-K-A-L-T-D-I-E-Q-S-K-S-D-A-I-S-A-V-K-T-E-M-S-D-L-T-V-L-L-A-E-K-I-M-G-A-N-L-D-K-T-A-Q-S-Q-L-I-D-S-Y-L-D-D-L-G-E-A"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-G-E-G-H-I-L-A-Q-N-K-K-A-R-L-D-Y-H-I-V-E-T-V-E-A-G-I-V-L-T-G-T-E-I-K-S-V-R-A-A-R-I-Q-L-K-D-G-F-A-Q-I-K-N-G-E-A-W-L-V-N-V-H-I-A-P-F-E-Q-G-N-I-W-N-A-D-P-E-R-T-R-K-L-L-L-K-K-R-E-I-T-H-L-A-N-E-L-K-G-T-G-M-T-L-V-P-L-K-V-Y-L-K-D-G-F-A-K-V-L-I-G-L-A-K-G-K-H-D-Y-D-K-R-E-T-I-K-R-R-D-Q-E-R-D-I-K-K-Q-M-K-H-Y-N-A-R"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-R-A-I-F-A-G-G-C-F-W-C-M-V-Q-P-F-E-E-Q-A-G-I-L-S-V-R-S-G-Y-T-G-G-H-L-P-N-P-S-Y-E-Q-V-C-A-K-T-T-G-H-T-E-A-V-E-I-I-F-D-P-E-E-I-S-Y-K-E-L-V-E-L-Y-W-A-Q-T-D-P-T-D-A-F-G-Q-F-E-D-R-G-D-N-Y-R-P-V-I-Y-Y-T-T-E-R-Q-K-E-I-A-E-Q-S-K-A-N-L-Q-A-S-G-R-F-D-Q-P-I-V-T-T-I-E-P-A-E-P-F-Y-L-A-E-D-Y-H-Q-G-F-Y-K-K-N-P-K-R-Y-A-Q-S-S-A-I-R-H-Q-F-L-E-E-N-W-S"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-N-A-I-I-E-T-A-K-E-R-F-A-Q-S-H-Q-S-L-S-R-E-Y-A-S-I-R-A-G-R-A-N-A-S-L-L-D-R-I-Q-V-D-Y-Y-G-A-P-T-P-L-N-Q-L-A-S-I-T-V-P-E-A-R-V-L-L-I-S-P-F-D-K-S-S-I-K-D-I-E-R-A-L-N-A-S-D-L-G-I-T-P-A-N-D-G-S-V-I-R-L-V-I-P-A-L-T-E-E-T-R-K-E-L-A-K-E-V-K-K-V-G-E-N-A-K-I-A-I-R-N-I-R-R-D-A-M-D-D-A-K-K-Q-E-K-A-K-E-I-T-E-D-E-L-K-T-L-E-K-D-I-Q-K-A-T-D-D-A-I-K-E-I-D-R-M-T-A-E-K-E-K-E-L-L-S-G"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-K-M-I-V-G-L-G-N-P-G-S-K-Y-E-K-T-K-H-N-I-G-F-M-A-I-D-N-I-V-K-N-L-D-V-T-F-T-D-D-K-N-F-K-A-Q-I-G-S-T-F-I-N-H-E-K-V-Y-F-V-K-P-T-T-F-M-N-N-S-G-I-A-V-K-A-L-L-T-Y-Y-N-I-D-I-T-D-L-I-V-I-Y-D-D-L-D-M-E-V-S-K-L-R-L-R-S-K-G-S-A-G-G-H-N-G-I-K-S-I-I-A-H-I-G-T-Q-E-F-N-R-I-K-V-G-I-G-R-P-L-K-G-M-T-V-I-S-H-V-M-G-Q-F-N-T-E-D-N-I-A-I-S-L-T-L-D-R-V-V-N-A-V-K-F-Y-L-Q-E-N-D-F-E-K-T-M-Q-K-F-N-G"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-I-W-H-W-L-I-V-L-V-I-V-L-L-V-F-G-T-K-R-L-T-S-G-A-K-D-L-G-S-A-V-K-E-F-K-K-G-M-H-D-D-D-K-P-A-G-K-L-G-D-D-S-R-S-A-E-Q-A-R-E-A-Q-A-E-R-D-R-D-A-R"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-S-E-L-A-L-I-A-V-V-A-L-V-V-L-G-P-E-R-L-P-K-A-A-R-F-A-G-L-W-V-R-R-A-R-M-Q-W-D-S-V-K-Q-E-L-E-R-E-L-E-A-E-E-L-K-R-S-L-Q-D-V-Q-A-S-L-R-E-A-E-G-Q-L-R-N-T-Q-Q-Q-V-E-D-G-A-R-G-L-H-D-Q-A-R-E-L-H-D-E-V-G-R-D-I-D-I-R-T-S-A-T-P-L-A-A-P-L-E-L-Q-A-D-A-P-V-V-L-E-P-G-S-A-Q-P-H-T-P-V-P-A-P-A-P-V-V-A-Q-A-Q-P-M-A-P-A-P-K-Q-T-L-V-P-A-P-H-G-S-L-T-S-T-Q-V-T-T-H-A-P-T-A-S-A-T-A-S-S-T-S-P-Q-E-K-T-P"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-S-P-L-S-I-V-L-L-G-F-A-M-S-T-D-A-F-A-A-A-I-G-K-G-A-A-M-R-R-P-R-W-R-D-A-V-R-A-G-L-V-F-G-C-I-E-A-I-T-P-V-I-G-W-M-L-G-R-A-A-S-D-Y-L-A-A-F-D-H-W-I-A-F-G-L-L-G-A-L-G-A-H-M-I-V-A-G-L-R-N-E-S-E-V-D-E-A-L-R-D-T-P-K-R-Y-G-L-L-A-L-A-A-T-G-F-A-T-S-I-D-A-M-A-V-G-V-S-L-A-F-L-D-V-H-I-G-V-V-A-A-V-V-G-L-C-T-L-S-M-V-T-A-G-V-M-L-G-R-A-L-G-A-L-I-G-K-R-A-E-I-L-G-G-V-I-L-I-L-I-G-S-T-I-L-Y-E-H-L-S-G-A-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-Q-S-L-Q-V-K-L-L-D-P-R-F-G-D-L-W-P-L-P-A-Y-A-T-E-A-S-A-G-M-D-L-R-A-A-L-E-A-P-M-T-L-E-P-G-D-A-A-L-I-P-S-G-I-A-I-H-L-D-D-P-Q-V-C-A-V-I-L-P-R-S-G-L-G-H-R-H-G-I-V-L-G-N-G-T-G-L-I-D-A-D-Y-Q-G-P-L-L-I-S-T-W-N-R-G-R-E-A-F-T-I-E-P-G-D-R-I-A-Q-L-V-I-L-P-I-V-R-V-S-L-Q-V-V-D-T-F-V-D-S-A-R-G-A-G-G-F-G-H-T-G-V-R"} +{"text": "### FUNCTION Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'--3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism ### SEQUENCE -M-E-T-L-R-Y-R-F-D-G-R-N-G-A-R-T-G-L-D-H-A-L-V-G-V-V-A-S-G-N-L-E-V-L-V-E-R-V-P-L-G-G-A-M-E-I-E-I-V-T-A-A-R-G-F-G-E-I-W-Q-A-V-L-D-D-F-A-A-R-H-S-L-Q-D-V-R-I-S-I-N-D-V-G-A-T-P-A-V-V-S-L-R-L-E-Q-A-I-D-V-L-Q-G-A-D-A"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-G-M-V-S-E-F-K-Q-F-A-M-R-G-N-V-I-D-L-A-V-G-V-V-I-G-A-A-F-G-K-I-V-T-A-L-V-E-K-I-I-M-P-P-I-G-W-A-I-G-N-V-D-F-S-R-L-A-W-V-L-K-P-A-G-V-D-A-T-G-K-E-I-P-A-V-V-I-G-Y-G-D-F-I-N-T-V-V-Q-F-V-I-I-A-F-A-I-F-L-V-V-K-L-I-N-R-L-S-Q-R-K-P-D-A-P-K-G-P-S-E-E-V-L-L-L-R-E-I-R-D-S-L-K-N-D-T-L-K-N-P-T-V-P"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-L-R-G-I-L-A-Y-K-Q-P-P-W-L-V-I-D-V-G-G-V-G-Y-E-L-E-A-P-M-S-T-F-Y-D-L-P-D-V-G-R-D-V-I-L-F-T-H-Y-A-Q-K-E-D-S-V-S-L-Y-G-F-L-R-E-G-E-R-R-L-F-R-D-V-Q-K-V-T-G-I-G-A-K-I-A-L-A-V-L-S-G-V-T-V-D-E-F-A-R-L-I-T-S-G-D-I-T-A-L-T-R-I-P-G-I-G-K-K-T-A-E-R-M-V-V-E-L-R-D-R-A-A-D-F-S-S-G-A-P-I-T-G-Q-L-G-P-D-A-V-S-E-A-T-V-A-L-Q-Q-L-G-Y-K-P-A-E-A-A-R-M-A-R-E-A-G-A-E-G-D-E-V-A-T-V-I-R-K-A-L-Q-A-A-L-R"} +{"text": "### FUNCTION Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone biosynthetic pathway ### SEQUENCE -M-S-T-I-S-R-D-S-C-P-A-L-R-A-G-V-R-L-Q-H-D-R-A-R-D-Q-W-V-L-L-A-P-E-R-V-V-E-L-D-D-I-A-L-V-V-A-Q-R-Y-D-G-T-Q-S-L-A-Q-I-A-Q-T-L-A-A-E-F-D-A-D-A-S-E-I-E-T-D-V-I-E-L-T-T-T-L-H-Q-K-R-L-L-R-L"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-E-I-P-G-D-L-K-F-L-K-S-H-E-W-A-R-V-E-G-N-G-R-V-T-V-G-I-S-D-H-A-Q-G-L-L-G-D-L-V-Y-V-E-L-P-A-V-G-D-T-V-Q-A-G-N-G-A-A-V-V-E-S-V-K-A-A-S-D-V-Y-S-P-V-T-G-T-V-V-E-V-N-A-S-L-S-D-K-P-E-T-I-N-E-D-A-Y-G-E-G-W-I-F-V-V-E-I-D-D-K-E-Q-L-N-E-L-L-A-P-D-D-Y-A-E-L-L-E-D-D-A-H"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-E-A-G-A-I-R-P-D-A-T-V-L-G-F-D-V-G-S-R-R-I-G-V-A-V-G-T-A-L-G-A-G-A-R-A-V-A-V-I-N-V-H-A-N-G-P-D-W-V-A-L-D-R-V-H-K-E-W-R-P-A-G-L-V-V-G-D-P-L-T-L-D-D-K-D-Q-P-A-R-K-R-A-H-A-F-A-R-E-L-R-E-R-Y-A-L-P-V-V-L-I-D-E-R-S-S-S-V-E-A-A-Q-R-F-A-R-E-R-A-D-G-R-K-R-R-R-D-A-D-T-L-D-A-M-A-A-A-V-I-V-E-R-W-L-S-A-P-E-Q-A-T-L-L-P"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-R-G-I-N-K-V-I-L-V-G-N-L-G-N-D-P-D-T-K-Y-T-Q-A-G-M-A-I-T-R-V-S-L-A-T-T-S-M-R-K-D-R-E-G-N-N-Q-E-R-T-E-W-H-R-V-V-F-F-G-K-L-G-E-I-A-G-E-Y-L-R-K-G-S-Q-V-Y-V-E-G-E-L-R-Y-D-K-Y-T-G-Q-D-G-V-E-K-Y-S-T-D-I-V-A-N-E-M-Q-M-L-G-G-R-G-E-G-G-G-G-G-G-M-G-G-D-R-P-Q-R-T-Q-A-P-R-Q-Q-Q-G-G-G-G-G-G-G-G-Q-D-Y-A-P-R-R-Q-Q-P-A-Q-Q-Q-S-A-P-P-M-D-D-F-A-D-D-D-I-P-F"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-C-R-L-I-A-T-G-E-R-A-P-A-W-V-A-Q-G-F-A-E-Y-Q-K-R-L-S-H-W-M-P-L-E-L-V-E-I-E-P-G-L-R-G-K-G-R-D-A-Q-R-A-I-D-D-E-G-R-R-V-L-A-A-L-P-K-N-A-H-V-V-A-L-D-V-P-G-R-P-L-S-S-E-Q-L-A-Q-R-M-E-H-W-R-G-Q-G-R-D-L-A-F-L-I-G-G-P-E-G-H-A-A-D-V-V-K-S-A-N-E-S-W-S-I-G-P-L-T-L-P-H-M-L-V-R-L-I-V-A-E-Q-L-Y-R-A-A-A-M-L-A-N-H-P-Y-H-R-A"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-K-K-S-L-N-E-S-S-P-V-A-R-F-E-Q-S-L-E-E-L-E-Q-L-V-Q-K-M-E-V-G-E-M-S-L-E-Q-S-L-T-A-Y-E-R-G-I-G-L-Y-R-D-C-Q-Q-A-L-E-Q-A-E-L-R-V-R-L-V-T-D-P-A-R-P-E-Q-A-E-A-F-E-P-P-S-L-D-G-G"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-S-R-W-R-P-P-A-E-K-S-T-A-L-I-T-P-E-G-H-A-R-L-K-A-E-L-D-E-L-W-R-L-R-R-P-E-V-V-R-A-L-A-A-A-A-A-E-G-D-R-S-E-N-A-E-Y-T-Y-R-K-K-Q-L-G-E-I-D-R-R-V-R-Y-L-S-K-R-L-E-A-L-R-V-V-D-T-A-P-T-D-P-Q-A-V-F-F-G-A-Q-V-E-L-E-D-A-D-S-G-E-L-L-R-Y-R-I-V-G-P-D-E-T-D-A-G-R-G-W-I-S-I-D-S-P-L-A-R-A-L-L-K-K-R-V-D-D-E-F-E-A-Q-L-P-S-G-K-H-T-F-V-V-V-V-V-E-Y-A-A-T"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-E-K-A-T-E-I-A-N-L-L-G-P-T-V-E-S-L-G-L-E-L-L-G-V-E-Y-L-P-A-P-G-G-A-T-L-R-L-Y-I-D-V-P-L-A-E-Q-P-D-R-I-I-N-V-D-D-C-E-R-V-S-R-E-V-S-A-Q-L-D-V-E-D-P-I-S-G-N-Y-T-L-E-V-S-S-P-G-V-D-R-P-L-F-T-L-D-Q-F-A-R-H-V-G-E-S-A-K-I-V-L-K-L-A-Q-D-G-R-R-R-F-Q-G-Q-I-V-R-I-D-T-E-A-A-A-V-V-F-S-V-D-G-K-D-V-Q-I-G-F-D-N-I-D-K-A-R-I-L-P-D-W-V-A-L-G-L-A-P-Q-K-P-N-K-P-G-P-K-K-P-G-H-D-K-K-K-P-S-N-E-P-A-A-G-K-P-R-A-E"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-T-M-P-T-K-S-F-H-R-T-D-R-V-S-A-Q-V-R-R-D-L-G-T-I-V-H-A-A-V-R-D-H-G-L-P-S-V-S-V-S-D-V-E-I-S-R-D-L-A-H-A-K-V-F-V-T-A-L-Q-Q-E-R-S-A-E-A-V-K-G-L-K-E-I-A-G-Q-L-R-T-Q-L-A-R-A-M-K-L-R-H-V-P-E-L-H-F-H-Y-D-D-S-V-D-R-G-E-R-I-D-N-L-L-R-D-L-D-D-I-G-P-E-A-A-P-D-A-Q-D-A-E-P-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-V-D-T-Q-K-V-I-E-D-N-K-R-S-A-Q-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-R-I-E-L-L-T-G-H-F-K-T-H-K-K-D-H-H-S-R-R-G-L-L-Q-M-V-N-R-R-R-S-L-L-D-Y-L-K-K-K-D-G-E-R-Y-K-S-L-I-E-K-L-G-L-R-R"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-P-L-G-D-C-N-I-S-T-P-D-N-K-Q-N-R-K-N-Q-E-I-R-V-P-R-V-R-V-I-G-S-D-G-E-M-V-G-V-L-S-R-D-E-A-L-A-K-A-E-E-E-G-L-D-L-V-E-I-Q-P-Q-A-D-P-P-V-C-K-I-M-D-F-G-K-F-K-F-E-Q-Q-K-K-A-N-E-A-K-K-K-T-K-Q-V-E-I-K-E-L-K-F-R-P-V-T-D-E-G-D-Y-Q-I-K-L-R-N-M-R-R-F-L-E-E-G-D-K-V-K-V-N-I-R-F-R-G-R-E-M-S-H-Q-E-L-G-R-E-M-A-A-R-I-E-A-D-L-G-E-D-I-V-I-E-S-R-P-R-L-E-G-R-Q-M-V-M-M-I-A-P-K-K-K-I"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-Q-A-R-R-R-H-K-K-I-L-T-L-A-K-G-Y-Y-N-A-R-R-K-V-F-R-V-A-K-Q-A-V-I-K-A-Q-Q-Y-A-Y-I-G-R-K-Q-K-K-R-N-F-R-S-L-W-I-T-R-I-N-A-A-A-R-I-N-G-L-S-Y-S-R-F-M-N-G-M-L-K-A-G-I-T-L-D-R-K-V-L-A-D-I-A-V-H-D-A-A-G-F-A-A-L-A-E-K-A-K-G-A-L-A-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-Q-Y-Q-Q-C-D-T-E-G-L-D-F-A-P-Y-P-G-E-L-G-Q-R-I-F-A-Q-I-G-K-A-G-W-Q-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-D-P-K-H-R-A-F-L-E-A-E-L-Q-K-F-L-F-E-R-N-A-D-K-P-E-G-Y-V-D-P-L-G-E-E"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-K-G-P-V-R-L-D-V-G-V-S-Y-A-L-P-R-T-G-L-P-S-S-V-S-F-R-K-W-V-A-A-A-L-K-G-R-I-R-E-A-D-L-A-V-R-V-V-D-E-K-E-G-C-S-L-N-H-H-Y-R-G-K-D-Y-A-T-N-V-L-S-F-P-A-E-M-P-Q-G-L-P-K-G-V-K-M-P-L-L-G-D-L-V-I-C-A-P-V-V-A-R-E-A-A-E-Q-G-K-S-L-S-A-H-Y-A-H-L-T-V-H-G-T-L-H-L-L-G-W-D-H-E-D-D-K-E-A-D-A-M-E-Q-L-E-R-E-I-L-A-E-L-G-I-D-D-P-Y-A-G-E-R"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-T-V-G-M-N-D-V-K-N-G-M-K-I-L-V-N-N-E-P-A-V-I-T-E-T-E-Y-V-K-P-G-K-G-Q-A-F-T-R-M-K-Y-R-F-I-K-S-G-R-V-V-E-M-T-M-K-A-T-D-D-V-E-V-A-D-V-V-D-T-D-M-R-Y-L-Y-T-D-G-E-Y-W-H-F-M-D-P-E-S-F-E-Q-V-Q-A-D-K-A-G-M-G-G-A-E-K-W-L-K-G-E-E-D-C-I-V-T-L-W-N-G-A-P-I-W-V-Q-P-P-N-F-V-E-L-K-I-T-E-T-D-P-G-V-R-G-D-T-S-G-G-G-G-K-P-A-T-L-E-T-G-A-V-V-R-V-P-L-F-V-N-Q-D-E-V-I-K-V-D-T-R-S-G-E-Y-S-A-R-V-K"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-I-L-A-R-R-Q-A-H-L-K-S-D-D-V-D-L-A-V-K-S-L-L-E-M-M-G-Q-A-L-S-D-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-P-P-R-L-G-R-N-P-K-T-G-E-S-V-A-L-P-G-K-H-V-P-H-F-K-P-G-K-E-L-R-E-R-V-S-S-V-V-P-V-D-M-V-D-A-A-D"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-D-N-V-A-G-N-D-R-L-I-W-I-D-L-E-M-T-G-L-D-T-D-R-D-S-I-I-E-I-A-T-I-V-T-D-A-Q-L-N-V-L-A-E-G-P-E-L-A-I-A-H-S-L-E-T-L-E-A-M-D-E-W-N-R-N-Q-H-R-R-S-G-L-W-Q-R-V-L-D-S-Q-V-T-H-A-Q-A-E-A-Q-T-V-A-F-L-S-E-W-I-R-A-G-A-S-P-M-C-G-N-S-I-C-Q-D-R-R-F-L-H-R-Q-M-S-R-L-E-R-Y-F-H-Y-R-N-L-D-V-S-T-I-K-E-L-A-R-R-W-A-P-A-V-A-S-G-F-A-K-S-S-A-H-T-A-L-S-D-V-R-D-S-I-D-E-L-R-H-Y-R-Q-F-M-G-T-L-G-G-D-N-G-G-G-V-Q-N"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-E-K-E-M-D-E-D-T-L-L-K-K-L-R-W-R-C-R-R-G-M-R-E-L-D-Q-L-F-G-R-Y-L-D-R-R-W-A-Q-A-P-A-A-E-R-A-V-F-L-Q-L-L-D-C-E-D-D-K-L-W-R-W-F-M-G-Y-E-A-C-P-D-A-D-N-A-A-L-I-A-D-I-R-A-M-P-A"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-Q-I-S-D-K-A-Q-T-Y-F-R-K-L-I-E-R-E-G-V-P-G-M-G-V-R-L-S-A-V-D-A-G-T-P-R-A-D-A-K-L-E-F-A-E-P-A-D-L-S-G-D-E-W-A-I-D-C-D-G-F-T-L-Y-V-V-A-A-S-V-P-W-M-D-G-A-E-I-D-Y-V-T-Q-S-T-G-N-Q-Q-L-T-I-K-A-P-K-I-K-G-E-A-P-A-E-S-A-S-M-V-E-R-V-R-W-V-V-E-N-E-I-N-P-Q-L-A-S-H-G-G-R-V-A-V-Q-E-V-S-A-E-G-V-V-L-L-R-F-G-G-G-C-H-G-C-G-M-A-D-V-T-L-K-Q-G-I-E-K-T-L-M-G-R-L-P-G-V-I-A-V-R-D-A-T-D-H-A-T-G-D-A-P-Y-I-P-R-D-S-A-A"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-S-I-E-F-E-G-S-V-S-E-T-L-P-N-T-T-F-R-V-K-L-E-N-G-Y-E-I-I-A-H-I-S-G-R-M-R-K-N-Y-I-R-I-L-T-G-D-R-V-K-V-E-M-T-P-Y-D-L-T-K-G-R-I-T-Y-R-M-K"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-P-R-K-T-S-H-E-H-D-H-G-L-V-V-E-T-S-K-P-E-V-A-P-P-P-R-Y-Q-V-L-L-L-N-D-D-Y-T-P-M-D-F-V-V-T-V-L-Q-Q-F-F-N-L-E-L-E-R-A-T-Q-V-M-L-H-V-H-T-R-G-R-G-V-C-G-V-Y-S-R-E-V-A-E-S-K-V-A-Q-V-N-E-F-S-R-M-N-Q-H-P-L-L-C-T-M-E-Q-A"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-S-T-A-V-Q-V-D-D-V-M-R-Y-R-D-S-R-F-Q-T-I-A-A-K-L-L-P-T-Q-Y-L-V-V-D-D-D-T-A-L-T-T-T-L-G-S-C-V-A-A-C-L-R-D-P-V-L-K-I-G-G-M-N-H-F-L-L-P-E-G-Q-V-G-D-G-A-P-A-R-Y-G-S-Y-A-M-E-L-L-I-N-D-M-L-K-R-G-A-H-R-K-R-I-E-A-K-V-F-G-G-A-N-V-L-K-G-F-T-S-N-P-V-G-T-R-N-A-E-F-V-R-Q-Y-L-Q-A-E-H-I-P-I-I-A-E-D-L-C-G-I-H-P-R-K-V-W-F-F-P-T-T-G-R-V-V-V-Q-R-L-P-H-A-H-E-A-E-V-A-A-A-E-S-A-V-R-A-R-L-S-K-A-P-V-T-G-G-V-E-L-F-E"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-M-I-G-D-L-V-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-I-D-A-P-K-D-V-A-V-H-R-E-E-I-Y-Q-R-I-Q-R-G-D-E-P-V-A-S-G-A-H-H-N-D-D-C-S-D"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-S-E-Q-A-P-A-P-K-R-G-R-R-F-K-E-Q-T-P-V-Q-R-A-L-G-L-L-V-R-R-E-H-S-K-K-E-L-N-R-K-L-Q-A-R-G-I-E-P-E-A-A-Q-A-A-V-E-R-L-A-G-E-G-W-Q-D-D-V-R-F-A-A-S-V-V-R-N-R-A-S-S-G-Y-G-P-L-H-I-R-A-E-L-G-T-H-G-L-D-S-D-A-V-S-A-A-M-A-T-F-E-G-D-W-T-E-N-A-L-D-L-I-R-R-R-F-G-E-D-G-P-V-D-L-A-Q-R-R-K-A-A-D-L-L-A-R-R-G-F-D-G-N-S-I-R-L-A-T-R-F-D-L-E-D"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-V-P-V-S-V-Y-L-V-N-G-I-K-L-Q-G-T-I-E-S-F-D-Q-F-V-V-L-L-R-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-N-V-R-V-G-P-G-G-G-Y-V-Q-S-N-E-N-N-Q-A-E-D-D-D-V-E-Q"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-D-L-I-L-L-Q-K-V-T-N-L-G-N-L-G-D-K-V-S-V-K-P-G-Y-G-R-N-F-L-V-P-Q-G-K-A-V-P-A-T-A-A-N-V-E-A-F-E-T-K-R-A-E-Y-E-A-K-A-N-T-I-L-A-D-A-Q-S-R-A-T-K-F-E-G-A-S-V-T-I-G-A-H-A-S-T-E-G-K-L-Y-G-S-V-G-P-R-D-I-A-E-A-F-T-A-A-G-L-P-L-E-K-S-E-V-I-L-G-E-G-A-F-R-N-V-G-E-Y-D-V-V-L-H-L-H-A-D-V-E-T-T-V-K-V-I-V-E-S-D-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-K-F-F-R-R-R-K-F-C-K-F-T-A-E-G-V-K-E-I-D-Y-K-D-L-N-T-L-R-Q-Y-L-T-E-N-G-K-I-V-P-S-R-V-T-G-T-K-S-K-Y-Q-R-Q-L-A-T-A-V-K-R-S-R-F-L-A-L-I-P-Y-T-D-N-H-D-V"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-R-H-Y-E-V-V-F-L-V-H-P-D-Q-S-E-Q-V-P-A-M-I-E-R-Y-K-S-L-I-E-G-G-N-G-T-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-Q-N-L-V-K-A-H-Y-V-L-L-N-I-E-V-D-Q-A-V-L-S-E-L-V-E-S-F-R-F-N-D-A-V-L-R-H-L-V-I-K-R-D-G-P-D-T-E-Q-S-L-I-M-K-S-K-D-E-K-G-D-K-P-E-R-S-E-R-R-R-R-D-D-E-E-G-D-A-A-P-A-A-T-D-T-D-G-D-N-A-E-A-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-Q-D-H-P-E-F-D-S-E-D-L-S-Q-N-P-P-E-T-D-P-L-K-A-E-I-E-S-L-R-S-E-I-A-L-V-K-A-D-A-L-R-E-R-A-D-L-E-N-Q-R-K-R-I-A-R-D-V-E-N-A-R-K-F-A-N-E-K-L-L-G-E-L-L-P-V-F-D-S-L-D-A-G-L-T-A-A-G-T-E-P-S-P-L-R-D-G-L-D-L-T-Y-K-Q-L-L-K-V-A-A-D-N-G-L-T-L-L-D-P-V-G-Q-P-F-N-P-D-Q-H-Q-A-I-S-Q-G-E-A-E-G-I-A-P-G-H-V-V-Q-V-F-Q-K-G-Y-L-L-N-E-R-L-L-R-P-A-L-V-V-V-A-K-H-D"} +{"text": "### FUNCTION Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ### SEQUENCE -M-R-N-L-L-L-V-A-A-V-A-L-S-T-A-G-C-G-I-I-Y-K-Q-P-I-Y-Q-G-N-L-I-K-Q-T-A-V-E-Q-L-Q-V-G-Q-S-K-Q-Q-V-S-A-L-L-G-T-P-S-I-P-D-P-F-H-A-Q-R-W-D-Y-T-S-T-Q-R-V-D-R-L-A-R-T-D-V-K-N-F-T-V-F-F-E-N-E-Q-V-V-R-W-E-G-D-Y-F-P-A-Q-D-E-Q-L-A-K-S-A-P-K-Q-F-G-R-N-L-A-R-D-K-K-K-Q-R-G-R"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-K-K-P-A-K-D-K-A-K-S-A-T-A-T-K-T-I-A-L-N-K-R-A-R-H-E-Y-H-L-E-E-R-Y-E-A-G-L-A-L-Q-G-W-E-V-K-A-I-R-A-G-R-A-N-I-V-D-G-Y-A-Y-V-R-S-G-E-I-Y-L-I-G-A-Q-I-T-P-L-I-Q-A-S-T-H-V-I-P-V-E-R-R-D-R-K-L-L-L-H-R-A-E-I-D-K-V-L-T-R-V-E-R-E-G-Y-T-L-V-P-T-A-L-Y-W-S-S-N-K-V-K-L-E-I-A-L-A-K-G-K-Q-S-H-D-K-R-D-A-A-K-E-R-D-W-Q-R-D-K-Q-R-V-M-R-R-H-N-R-D-A"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-N-Q-I-K-Q-D-A-Q-T-R-M-T-K-S-I-D-A-L-R-H-S-L-T-T-V-R-T-G-R-A-S-P-A-L-L-D-N-I-K-V-K-A-Y-G-T-D-T-P-L-N-Q-V-A-S-I-S-V-S-E-G-R-S-L-V-I-S-L-F-D-K-G-M-I-K-D-V-E-K-A-I-Y-A-S-D-L-G-L-T-P-T-V-V-G-T-V-I-R-L-N-L-P-P-L-T-E-E-R-R-K-E-L-S-K-S-V-H-G-E-G-E-D-A-K-V-A-I-R-N-I-R-R-D-A-N-Q-Q-V-K-D-L-L-K-D-K-Q-V-T-E-D-E-A-R-G-A-E-D-D-I-Q-K-L-T-D-K-A-I-K-D-V-D-E-V-V-K-G-K-E-Q-E-L-M-T-V"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-K-L-N-K-T-I-L-A-D-F-E-A-A-Q-I-Q-R-Q-L-P-E-F-N-Q-G-D-T-V-V-V-N-V-K-V-K-E-G-N-R-E-R-V-Q-A-Y-E-G-V-V-I-G-T-K-N-A-G-L-N-S-A-F-T-V-R-K-I-S-H-G-F-G-V-E-R-V-F-Q-T-H-S-A-I-I-D-S-V-E-V-K-R-R-G-K-V-R-A-G-K-L-Y-Y-L-R-G-L-E-G-K-A-A-R-I-K-E-D-L-A-A-A-A-Q-A-K-A-A-R-Q-A-A-A-K-A-E"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-P-T-E-R-R-I-L-L-G-R-I-V-G-A-F-G-V-K-G-E-L-K-L-E-S-W-T-E-P-R-S-A-I-F-R-Y-Q-P-W-I-V-R-T-P-S-G-Q-E-S-V-L-S-G-V-R-G-R-D-Q-G-K-N-L-I-A-V-F-P-D-I-T-D-R-D-T-V-E-A-M-H-G-T-E-I-Y-V-A-R-S-A-L-P-P-P-K-P-D-E-Y-Y-W-V-D-L-E-G-L-Q-V-E-T-V-E-G-V-K-L-G-T-V-S-H-L-F-S-T-G-S-N-D-V-V-V-V-R-G-D-R-E-R-M-I-P-F-V-L-P-E-Y-V-K-S-V-D-F-E-A-N-L-I-V-V-D-W-D-P-D-F"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-R-A-K-Q-T-V-V-R-N-E-R-N-T-G-Q-R-S-M-L-R-T-A-V-K-K-V-I-K-A-L-D-A-N-D-A-A-G-A-E-A-A-F-A-V-A-Q-P-I-L-D-R-F-S-A-R-G-L-I-H-K-N-K-A-A-R-H-K-S-R-L-T-A-R-I-K-A-I-K-A-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-L-V-T-G-G-K-Q-Y-R-V-A-Q-G-E-T-L-R-V-E-K-L-E-V-E-A-G-N-E-I-K-F-D-T-I-L-M-L-G-D-S-D-G-I-K-L-G-D-A-L-K-G-A-S-V-T-A-K-V-V-A-H-G-R-A-D-K-V-R-I-I-K-F-R-R-R-K-H-H-M-K-R-Q-G-H-R-Q-Y-Y-T-E-I-E-I-T-G-I-A-G-G-D-K-K"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-G-L-L-D-F-L-K-S-K-K-N-T-A-E-T-A-K-N-R-L-Q-I-I-I-A-Q-E-R-N-H-R-G-G-P-D-Y-L-P-L-M-Q-R-E-L-L-E-V-I-K-K-Y-V-N-I-D-A-D-A-V-R-V-D-L-V-K-D-G-E-H-D-V-L-D-I-T-V-A-L-P-E-D-G-D-K"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-M-P-R-L-I-L-A-S-T-S-A-Y-R-R-E-L-L-G-R-L-H-L-D-F-D-T-A-R-P-E-V-D-E-H-A-L-P-G-E-T-P-Q-A-L-A-T-R-L-A-G-E-K-A-R-A-V-A-V-R-F-P-E-A-W-V-I-G-S-D-Q-V-A-D-L-D-G-Q-A-L-G-K-P-G-T-L-E-Q-A-R-A-Q-L-T-R-M-S-G-R-M-V-R-F-Q-T-A-V-S-L-I-G-P-D-G-F-A-A-Q-A-L-D-L-T-D-V-Q-V-R-P-L-Q-P-Q-E-I-E-R-Y-L-A-A-E-P-A-L-E-C-A-G-S-F-K-C-E-G-L-G-I-T-L-F-D-A-I-R-S-N-D-P-T-A-L-V-G-L-P-L-I-A-V-A-R-L-L-R-Q-A-G-F-S-L-P"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-S-L-L-E-Q-L-I-E-A-F-R-V-L-P-G-V-G-Q-K-S-A-Q-R-M-A-Y-H-V-L-E-R-E-R-E-G-G-R-R-L-A-A-A-L-A-N-A-V-E-K-V-G-H-C-V-Q-C-R-D-F-T-E-S-E-V-C-A-I-C-A-N-S-G-R-D-R-Q-Q-L-C-V-V-E-S-P-A-D-R-L-A-I-E-H-A-T-G-Y-R-G-V-Y-F-I-L-Q-G-R-L-S-P-L-D-G-I-G-P-R-E-L-G-L-D-R-L-A-E-R-L-A-A-G-E-V-T-E-M-I-I-A-T-N-A-T-V-E-G-E-A-T-A-H-Y-L-A-Q-L-A-R-Q-H-S-V-R-P-S-R-L-A-Q-G-M-P-L-G-G-E-L-E-Y-V-D-R-G-T-L-S-H-A-F-G-T-R-S-E-V-L"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-R-G-N-I-A-Q-L-M-Q-Q-A-Q-K-M-Q-E-N-L-Q-R-A-Q-E-E-L-A-K-L-E-V-T-G-S-A-G-G-G-M-V-S-V-T-L-T-G-A-K-E-C-R-K-V-R-I-D-P-S-I-L-S-D-Q-E-M-A-E-D-L-I-A-A-A-F-N-D-A-S-N-K-I-D-A-E-S-K-E-R-M-G-S-A-T-A-G-M-Q-L-P-P-G-M-K-L-P-F"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-N-P-F-R-W-G-F-R-A-Q-F-L-L-G-F-L-A-C-A-G-L-L-A-Y-A-I-Y-V-Q-L-H-L-G-L-E-P-C-P-L-C-I-F-Q-R-I-A-F-A-T-L-A-L-L-F-L-L-G-A-L-H-G-P-R-G-A-G-G-R-K-A-Y-G-V-L-A-F-I-A-A-G-V-G-M-G-I-A-A-R-H-V-W-V-Q-I-R-P-K-D-M-M-S-S-C-G-P-P-L-S-F-L-S-E-T-M-G-P-F-E-V-F-R-T-V-L-T-G-T-G-D-C-G-N-I-D-W-R-F-L-G-L-S-M-P-M-W-S-M-V-W-F-V-G-L-A-L-W-A-L-Y-A-G-F-K-H-R-G-P-R-K-L-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-M-H-L-N-D-L-K-P-A-D-G-A-R-T-E-R-T-R-V-G-R-G-I-G-S-G-L-G-K-T-C-G-R-G-H-K-G-S-F-A-R-K-G-G-G-K-I-K-A-G-F-E-G-G-Q-T-P-M-Q-R-R-L-P-K-I-G-F-R-S-K-M-A-R-D-S-A-E-V-L-S-Y-Q-L-D-K-L-E-A-G-E-I-D-F-A-A-L-R-A-A-N-L-V-P-S-R-A-K-K-A-K-I-V-L-K-G-E-L-S-K-K-F-V-L-K-G-V-A-A-T-A-G-A-K-A-A-I-E-A-A-G-G-S-V-E-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-I-N-K-N-I-A-R-L-R-R-A-K-S-T-R-A-H-I-R-E-L-G-V-A-R-L-S-V-L-R-T-G-Q-H-L-Y-A-Q-V-F-T-A-D-G-S-K-V-I-A-A-A-N-T-L-Q-A-D-V-K-D-G-L-K-N-G-K-N-S-D-A-A-V-K-V-G-K-L-I-A-E-R-A-K-A-A-G-I-E-K-V-A-F-D-R-S-G-Y-R-Y-H-G-R-I-K-A-L-A-D-A-A-R-E-G-G-L-Q-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-K-P-V-S-L-P-K-G-V-E-L-N-V-Q-P-E-L-I-S-V-K-G-P-K-G-T-L-T-L-Q-K-P-V-G-V-E-I-A-I-D-G-D-V-A-T-L-S-A-N-D-P-S-Q-I-A-I-T-G-T-V-R-A-I-L-A-N-M-I-K-G-V-S-E-G-F-E-R-K-L-E-L-V-G-V-G-Y-R-A-A-M-Q-G-K-D-L-S-L-A-L-G-F-S-H-P-L-V-F-V-A-P-E-G-I-T-L-S-T-P-T-Q-T-E-I-L-V-Q-G-A-D-K-Q-R-V-G-E-V-A-A-K-I-R-G-F-R-P-P-E-P-Y-K-G-K-G-V-K-Y-A-G-E-V-I-I-R-K-E-A-K-K-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-T-D-P-I-A-D-L-L-V-R-I-K-N-A-A-A-V-G-K-Q-T-V-K-L-P-S-S-K-I-K-V-A-I-A-Q-V-L-K-D-E-G-Y-I-T-D-L-R-V-T-A-T-E-N-N-K-S-E-L-E-I-V-L-K-Y-F-E-G-R-P-V-I-E-T-L-K-R-F-S-R-S-G-L-R-Q-Y-R-G-K-T-E-L-P-K-V-L-G-G-L-G-I-A-I-I-S-T-S-K-G-I-M-T-D-A-Q-A-R-E-A-G-V-G-G-E-V-L-C-F-V-A"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-T-R-L-E-K-F-Y-K-E-N-V-V-P-A-L-M-K-E-F-G-Y-T-N-P-M-E-V-P-K-L-V-K-V-T-L-N-M-G-V-G-E-A-A-T-N-K-K-I-L-E-N-A-V-A-D-M-S-K-I-S-G-Q-K-P-V-V-T-K-S-R-V-S-V-A-S-F-K-I-R-D-G-W-P-I-G-C-K-T-T-L-R-R-A-K-M-Y-E-F-L-D-R-L-I-N-I-S-L-P-R-V-R-D-F-R-G-V-S-G-R-S-F-D-G-R-G-N-F-N-M-G-V-K-E-Q-I-I-F-P-E-I-D-F-D-A-V-D-A-I-R-G-M-D-I-A-I-T-T-T-A-K-T-D-A-E-A-K-A-L-L-A-A-F-K-F-P-F-R-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-N-R-I-K-K-G-D-Q-V-V-I-N-T-G-K-D-K-G-K-Q-G-E-V-V-R-V-E-G-D-R-V-I-V-S-N-A-N-V-I-K-R-H-T-K-P-N-P-Q-A-G-V-A-G-G-V-V-E-R-E-A-S-I-H-I-S-N-V-N-I-V-N-P-A-T-G-K-G-E-R-V-G-F-K-V-L-E-D-G-R-K-L-R-V-F-R-S-S-G-E-A-L-D-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-D-N-N-E-K-Q-T-L-R-T-V-E-G-R-V-V-S-N-K-M-D-K-T-V-T-V-L-V-E-R-Q-V-K-H-P-L-Y-G-K-Y-I-K-R-S-S-K-L-H-A-H-D-A-D-N-A-C-N-E-G-D-V-V-R-V-T-E-I-A-P-M-S-K-T-K-N-W-R-V-V-E-I-V-T-R-A-A-V"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-Y-R-K-M-H-K-G-R-N-D-G-L-A-W-S-G-N-A-V-S-F-G-E-Y-G-L-K-A-T-A-H-G-Q-L-T-A-R-Q-I-E-A-A-R-R-T-I-S-R-H-V-K-K-G-G-K-M-W-I-R-V-F-P-D-K-P-I-T-K-K-P-I-E-V-R-M-G-S-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-R-M-I-Y-E-I-E-G-I-P-E-D-I-A-R-E-A-F-R-L-A-A-A-K-L-S-V-T-T-T-F-V-T-R-T-V-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-V-D-H-H-L-A-K-K-V-E-S-A-A-G-S-K-K-P-I-K-T-W-S-R-R-S-M-I-L-P-E-M-V-G-I-T-I-A-V-H-N-G-K-N-H-I-P-V-L-V-N-E-N-M-V-G-H-K-L-G-E-F-A-V-T-R-T-F-K-G-H-G-G-D-K-K-S-S-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-S-N-E-K-I-F-S-V-L-R-A-P-R-V-S-E-K-T-A-R-L-Q-E-I-S-N-Q-Y-V-F-E-V-S-N-E-A-T-K-A-D-V-K-A-A-V-E-Q-L-F-D-V-K-V-K-A-V-N-V-V-N-V-K-G-K-S-K-S-F-R-N-R-A-G-S-R-G-N-W-R-K-A-Y-V-R-L-V-D-G-Q-S-I-D-V-T-A-K-A"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-D-Q-K-I-R-I-R-L-K-A-F-D-H-R-L-I-D-R-S-A-S-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-K-I-E-R-Y-T-I-L-V-S-P-H-A-D-K-D-A-R-D-Q-Y-E-T-R-T-H-K-R-V-L-D-I-V-D-P-N-D-K-T-V-D-A-L-M-K-L-E-L-A-A-G-V-D-V-Q-I-K-L-T"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-G-S-T-P-Q-R-T-V-L-P-D-P-K-H-G-S-E-T-I-A-R-F-I-N-M-V-M-Q-S-G-K-K-S-V-A-E-K-I-V-Y-G-A-M-D-V-I-G-E-K-N-P-N-A-V-E-L-V-Q-K-A-L-D-N-V-A-P-A-V-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-S-S-R-R-M-A-L-A-M-R-W-L-I-D-S-A-R-K-R-G-E-N-T-M-P-R-K-L-A-A-E-L-L-D-A-S-E-S-R-G-G-A-I-K-K-R-E-E-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-L-T-N-E-Q-I-V-D-A-I-A-E-K-S-L-M-E-V-M-E-L-V-K-A-I-E-E-K-F-G-V-S-A-A-A-P-V-A-A-A-A-A-G-P-A-A-V-V-E-E-Q-T-E-F-T-V-V-L-T-S-P-G-A-N-K-V-A-A-I-K-A-V-R-G-V-T-G-L-G-L-K-E-A-K-D-L-T-E-A-G-G-I-L-K-E-G-V-S-K-D-E-A-E-K-I-K-K-E-M-T-E-A-G-A-T-V-E-V-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-A-L-R-L-I-V-G-L-G-N-P-G-P-E-H-A-Q-T-R-H-N-A-G-F-R-F-V-D-A-L-A-E-R-T-G-A-R-W-G-L-D-S-K-L-F-G-E-T-A-K-A-E-I-A-G-H-T-V-W-L-L-K-P-A-T-F-M-N-L-S-G-K-S-I-T-A-A-L-R-F-W-K-I-E-P-E-Q-L-L-V-A-H-D-E-L-D-L-A-P-G-T-A-R-L-K-F-D-G-G-H-G-G-Q-N-G-L-R-D-T-I-R-L-L-G-H-G-K-F-H-R-L-R-V-G-I-G-H-P-G-H-K-D-R-V-V-P-W-V-L-G-R-A-G-R-D-D-D-M-A-I-G-E-A-V-D-A-A-I-D-A-L-P-L-A-L-D-G-N-F-N-E-A-M-K-R-L-H-T-P-K-K"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-S-R-L-L-L-I-V-L-L-A-C-S-I-A-S-A-I-G-V-V-Y-M-R-H-M-H-R-K-L-F-V-Q-L-S-K-L-E-H-S-R-D-E-L-N-I-E-F-G-R-L-Q-L-E-Q-A-T-W-A-E-S-N-R-V-D-Q-V-S-R-E-R-I-G-M-K-F-P-E-T-S-D-I-V-V-I-R-P"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-K-P-G-G-H-A-R-H-G-R-R-D-G-I-D-P-V-L-R-S-R-A-R-R-R-A-L-Q-A-V-Y-A-W-Q-I-A-G-G-F-A-K-Q-V-I-A-Q-F-A-H-E-Q-A-H-E-V-A-D-L-A-Y-F-E-S-L-V-E-G-V-L-S-N-R-S-E-L-D-T-A-L-T-P-Y-L-D-R-G-V-E-E-V-D-A-I-E-R-A-V-L-R-L-A-A-Y-E-L-L-Y-R-Q-D-V-P-Y-R-V-V-I-N-E-A-I-E-T-A-K-R-F-G-S-E-H-G-H-T-Y-V-N-G-V-L-D-R-A-A-V-E-W-R-K-M-E-S-G-A-S-G-A"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-Q-H-N-D-T-R-V-I-D-S-R-V-S-E-D-G-T-T-I-R-R-R-R-E-C-E-A-C-G-E-R-F-S-T-L-E-T-I-E-L-K-L-P-T-V-V-K-S-D-G-G-R-E-A-F-D-A-R-K-L-R-T-S-F-D-R-A-L-Q-K-R-P-V-S-E-E-Q-I-E-A-A-V-R-A-V-V-H-Q-L-R-M-S-G-E-R-E-V-G-S-L-R-V-G-E-Y-V-M-V-E-L-R-K-L-D-H-V-G-Y-V-R-F-A-S-V-Y-R-S-F-Q-D-V-A-D-F-R-E-E-I-E-K-L-E-R-E-L-P-V-G-S-E-Q-L-P-L-L-E-A-A-L-E-R-A-G-K-P-G-K-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-Q-A-L-T-L-A-R-P-Y-A-R-A-A-F-A-I-A-R-E-G-G-K-F-A-P-W-S-D-A-L-A-F-S-A-Q-V-A-G-D-P-R-V-A-A-L-L-L-N-P-A-L-H-Q-D-Q-A-V-T-L-L-A-P-P-A-A-E-A-D-Y-Q-R-F-L-G-L-L-A-D-A-Q-R-L-A-L-L-P-E-I-A-G-L-Y-E-Q-L-R-A-E-A-E-H-V-V-K-A-T-V-T-S-A-T-D-M-S-P-A-E-L-A-T-I-T-A-A-L-K-K-R-F-G-R-E-V-D-V-T-T-A-V-D-A-S-L-I-G-G-A-V-I-D-T-G-E-M-V-I-D-G-S-L-K-G-K-L-A-R-L-Q-N-S-L-A-H"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-I-T-L-T-I-F-A-Q-A-L-A-F-A-G-L-I-W-I-V-A-T-K-I-W-P-P-L-L-K-A-I-E-E-R-Q-Q-K-I-A-E-G-L-A-A-A-D-R-S-Q-K-D-L-A-Q-A-Q-E-K-V-N-E-A-L-K-D-A-R-T-K-A-N-E-I-I-D-Q-A-H-A-R-A-N-Q-I-I-E-A-A-K-L-E-A-I-A-E-A-N-R-Q-K-D-L-A-Q-A-E-I-D-A-S-A-T-R-A-R-E-E-L-R-R-Q-V-S-S-L-A-V-S-G-A-E-K-L-L-K-R-E-I-D-A-T-A-H-K-A-L-L-D-E-L-A-A-E-I"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-T-L-V-S-L-P-T-A-A-P-A-P-D-Y-Q-S-I-D-R-P-L-N-F-S-N-A-A-A-A-K-V-R-E-L-I-Q-E-E-G-N-A-E-L-A-L-R-V-Y-I-Q-G-G-G-C-S-G-F-Q-Y-G-F-E-F-D-E-N-R-A-E-D-D-L-A-V-A-T-D-G-V-T-L-L-V-D-P-L-S-L-Q-Y-L-M-G-A-E-V-D-Y-T-E-S-L-T-G-A-Q-F-V-I-R-N-P-N-A-K-T-T-C-G-C-G-S-S-F-S-V"} +{"text": "### FUNCTION Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA ### SEQUENCE -M-L-V-L-L-N-K-P-Y-G-V-L-S-Q-F-S-D-R-S-T-P-P-K-R-T-L-A-E-F-G-L-P-P-Q-V-Y-A-A-G-R-L-D-H-D-S-E-G-L-L-L-L-T-D-D-G-P-L-A-H-R-L-T-D-P-R-H-K-Q-P-K-T-Y-W-V-Q-V-E-G-D-P-D-T-S-Q-L-Q-A-L-C-D-G-V-L-L-N-D-G-P-T-R-P-A-N-V-R-R-L-E-C-A-P-T-L-W-P-R-D-P-P-V-R-V-R-K-T-V-P-D-A-W-L-E-V-Q-I-T-E-G-R-N-R-Q-V-R-R-M-T-A-S-V-G-L-P-T-L-R-L-V-R-V-A-I-G-A-W-S-L-A-S-L-Q-P-G-Q-W-R-V-D-D-A-R-A-V-R-P-A-R"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-D-E-I-L-N-G-A-A-A-P-A-D-A-A-A-G-P-A-F-T-I-E-K-I-Y-V-K-D-V-S-F-E-S-P-N-A-P-A-V-F-N-D-A-N-Q-P-E-L-Q-L-N-L-N-Q-K-V-Q-R-L-N-D-N-A-F-E-V-V-L-A-V-T-L-T-C-T-A-G-G-K-T-A-Y-V-A-E-V-Q-Q-A-G-V-F-G-L-V-G-L-E-P-Q-A-I-D-V-L-L-G-T-Q-C-P-N-I-L-F-P-Y-V-R-T-L-V-S-D-L-I-Q-A-G-G-F-P-P-F-Y-L-Q-P-I-N-F-E-A-L-Y-A-E-T-L-R-Q-R-S-Q-G-E-T-S-L-A-D-S-E-P-A-G-N-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-A-S-N-P-C-R-R-F-P-R-S-A-R-V-R-T-R-A-Q-Y-T-I-V-F-D-T-A-R-R-T-S-D-P-L-L-S-L-H-W-R-T-G-D-T-P-P-R-L-G-M-A-V-S-R-K-V-D-T-R-A-V-G-R-N-R-I-K-R-V-L-R-D-A-M-R-H-L-L-P-E-L-A-G-G-D-Y-V-I-V-A-R-S-A-A-A-K-A-T-N-P-Q-I-R-D-A-F-L-R-L-L-H-R-A-G-A-L-P-L-P-A-A-A-G-T-M-P-P-A-R-T-V-H-P-S-S-L-S-P-T-E-P-E-L"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-F-S-I-W-H-W-L-I-V-L-V-I-V-L-L-V-F-G-T-K-R-L-T-S-G-A-K-D-L-G-S-A-V-K-E-F-K-K-G-M-H-D-D-D-K-P-A-G-K-L-G-D-D-S-R-T-A-E-Q-A-R-E-A-Q-A-E-R-D-R-D-A-R"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-S-P-F-S-I-V-L-I-G-F-A-M-S-T-D-A-F-A-A-A-I-G-K-G-A-A-M-R-K-P-Q-W-R-D-A-L-R-A-G-L-I-F-G-C-I-E-A-I-T-P-V-I-G-W-L-L-G-R-A-A-A-S-Y-V-S-A-Y-D-H-W-I-A-F-V-L-L-G-A-L-G-T-H-M-I-V-A-G-L-R-N-G-P-E-D-A-E-D-A-A-S-D-T-P-K-R-H-G-V-L-G-L-A-T-T-G-F-A-T-S-I-D-A-M-A-V-G-V-S-L-A-F-L-D-V-H-I-G-V-V-A-V-V-V-G-L-C-T-F-S-M-V-T-A-G-V-M-L-G-R-A-L-G-N-L-I-G-K-R-A-E-M-L-G-G-L-I-L-V-I-V-G-S-V-I-L-Y-E-H-L-S-G-A-G"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-S-P-P-T-Q-S-L-Q-V-K-L-L-D-P-R-F-G-D-L-W-P-L-P-A-Y-A-T-E-S-S-A-G-M-D-L-R-A-A-L-E-A-P-M-T-L-Q-P-G-D-A-A-L-I-P-S-G-I-A-I-H-L-A-D-P-Q-L-C-A-V-I-L-P-R-S-G-L-G-H-R-H-G-I-V-L-G-N-G-T-G-L-I-D-A-D-Y-Q-G-P-L-L-I-S-T-W-N-R-G-R-E-A-F-T-I-E-P-G-D-R-I-A-Q-L-V-I-L-P-I-V-R-M-G-L-Q-V-V-D-T-F-V-D-S-A-R-G-A-G-G-F-G-H-T-G-V-R"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-L-L-P-I-L-E-F-P-D-P-R-L-R-T-K-A-V-P-V-D-A-A-E-V-T-S-Q-A-F-Q-T-L-L-D-D-M-F-H-T-M-Y-E-A-P-G-I-G-L-A-A-S-Q-V-D-V-H-K-R-F-M-V-I-D-I-S-D-E-K-N-L-P-Q-V-F-V-N-P-E-I-V-S-K-Q-G-E-Q-L-Y-Q-E-G-C-L-S-V-P-G-I-Y-A-D-V-S-R-A-D-A-I-T-V-R-Y-L-D-R-Q-G-Q-P-Q-E-L-H-A-D-G-L-L-A-V-C-I-Q-H-E-M-D-H-L-D-G-K-L-F-V-D-Y-L-S-P-L-K-R-E-M-V-R-K-K-L-A-K-Q-R-K-H-V-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-I-T-L-T-I-F-A-Q-A-L-A-F-A-G-L-I-W-I-V-A-T-K-I-W-P-P-L-L-Q-A-I-E-E-R-Q-Q-K-I-A-E-G-L-A-A-A-D-R-S-Q-K-D-L-A-Q-A-Q-E-K-V-N-E-A-L-K-D-A-R-T-K-A-N-E-I-I-D-Q-A-H-A-R-A-N-Q-I-I-E-A-A-K-L-E-A-I-A-E-A-N-R-Q-K-D-L-A-Q-T-E-I-D-A-S-A-T-R-A-R-E-E-L-R-K-Q-V-S-V-L-A-V-S-G-A-E-K-L-L-K-R-E-I-D-A-N-A-H-K-A-L-L-D-E-L-A-A-E-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-Q-A-L-T-L-A-R-P-Y-G-R-A-A-F-A-I-A-R-E-G-G-N-F-A-P-W-S-D-A-L-A-F-S-A-Q-V-A-G-D-P-R-V-A-A-L-L-L-N-P-A-L-G-Q-E-Q-A-V-T-L-L-A-P-P-Q-A-G-E-D-Y-L-R-F-L-G-V-L-A-D-A-Q-R-L-S-L-L-P-E-V-A-G-L-Y-E-H-L-R-A-E-A-E-H-V-V-K-A-T-V-T-S-A-A-A-M-S-Q-T-E-L-D-T-I-A-A-A-L-K-K-R-F-G-R-D-V-D-I-T-T-A-V-D-A-S-L-I-G-G-A-V-I-D-T-G-D-V-V-I-D-G-S-L-K-G-K-L-A-R-L-Q-S-S-L-A-H"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-T-I-R-C-D-I-V-S-A-E-K-E-I-F-H-G-E-A-T-L-V-V-A-T-G-E-L-G-E-L-G-I-A-P-K-H-A-P-L-I-T-R-L-K-P-G-K-V-V-V-T-T-A-N-G-E-Q-L-D-F-A-I-S-G-G-I-L-E-V-Q-P-Q-V-V-T-I-L-V-D-T-A-V-R-A-Q-D-I-D-E-A-A-V-R-K-V-K-E-E-A-E-R-L-L-A-N-R-G-N-T-V-D-V-A-E-A-Q-R-Q-L-A-E-A-T-V-Q-L-Q-A-L-E-R-L-R-R-N-L-K-H"} +{"text": "### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate forming two phosphate ions ### SEQUENCE -M-G-L-E-L-V-T-S-G-K-N-L-P-E-E-I-N-V-V-I-E-I-P-K-D-S-E-P-V-K-Y-E-V-D-K-A-S-G-A-I-F-V-D-R-I-L-S-T-P-M-R-Y-P-C-N-Y-G-Y-V-P-N-T-L-C-G-D-G-D-P-A-D-V-L-V-V-L-P-L-P-L-V-P-G-S-V-V-R-C-R-P-V-G-V-L-R-M-S-D-E-A-G-S-D-E-K-I-L-A-V-P-I-E-K-I-F-S-G-Y-A-H-I-E-D-I-N-Q-V-S-S-H-W-M-E-R-I-G-H-F-F-E-H-Y-K-D-L-E-K-G-K-W-V-K-L-D-G-W-G-G-A-A-E-A-K-R-I-L-T-E-S-V-E-R-Y-N-S-D-A-P"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-G-M-V-S-E-F-K-Q-F-A-M-R-G-N-V-I-D-L-A-V-G-V-V-I-G-A-A-F-G-K-I-V-T-A-L-V-E-K-I-I-M-P-P-I-G-W-A-I-G-N-V-D-F-S-R-L-A-W-V-L-K-P-A-G-V-D-A-T-G-K-E-I-P-A-V-A-I-G-Y-G-D-F-I-N-T-V-V-Q-F-L-I-I-A-F-A-I-F-L-V-V-K-L-I-N-R-V-T-H-R-K-P-D-A-P-K-G-P-S-E-E-V-L-L-L-R-E-I-R-D-A-L-K-N-D-T-L-K-P-P-G-A-L"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-L-R-G-I-L-A-Y-K-Q-P-P-W-L-V-I-D-V-G-G-V-G-Y-E-L-E-A-P-M-S-T-F-Y-D-L-P-D-V-G-R-D-V-I-L-F-T-H-Y-A-Q-K-E-D-S-V-S-L-Y-G-F-L-R-E-G-E-R-R-L-F-R-D-V-Q-K-V-T-G-I-G-A-K-I-A-L-A-V-L-S-G-V-S-V-D-E-F-A-R-L-I-T-S-G-D-I-T-A-L-T-R-I-P-G-I-G-K-K-T-A-E-R-M-V-V-E-L-R-D-R-A-A-D-F-S-S-G-A-P-I-T-G-Q-L-G-P-D-A-V-S-E-A-T-V-A-L-Q-Q-L-G-Y-K-P-A-E-A-A-R-M-A-R-D-A-G-A-E-G-D-E-V-A-T-V-I-R-K-A-L-Q-A-A-L-R"} +{"text": "### FUNCTION Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone biosynthetic pathway ### SEQUENCE -M-S-G-I-T-R-D-S-R-P-A-L-R-A-G-V-R-L-Q-Q-D-R-A-R-D-Q-W-V-L-L-A-P-E-R-V-V-E-L-D-D-I-A-L-V-V-A-Q-R-Y-D-G-T-R-S-L-A-Q-I-A-Q-E-L-A-A-E-F-D-A-D-A-A-Q-I-E-A-D-V-I-E-L-T-D-T-L-H-Q-K-R-L-L-R-L"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-E-I-P-G-D-L-K-F-L-K-S-H-E-W-A-R-V-E-S-N-G-R-V-T-V-G-I-S-D-H-A-Q-G-L-L-G-D-L-V-Y-V-E-L-P-G-V-G-D-T-V-Q-V-G-N-G-A-A-V-V-E-S-V-K-A-A-S-D-V-Y-S-P-V-S-G-T-V-V-E-V-N-S-A-L-S-D-K-P-E-T-I-N-E-D-A-Y-G-E-G-W-I-F-V-V-E-I-D-D-K-E-Q-L-N-D-L-L-D-P-D-D-Y-A-E-L-L-E-D-D-D-H"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-E-A-G-A-I-R-P-D-G-T-V-L-G-F-D-V-G-S-R-R-I-G-V-A-V-G-S-A-L-G-A-G-A-R-A-V-A-V-I-N-V-H-A-N-G-P-D-W-V-A-L-D-R-V-H-K-Q-W-R-P-D-G-L-V-V-G-D-P-L-T-L-D-D-K-D-Q-P-A-R-K-R-A-H-A-F-A-R-Q-L-R-E-R-Y-A-L-P-V-V-L-I-D-E-R-S-S-S-V-E-A-A-Q-R-F-A-R-E-R-A-D-G-R-K-R-R-R-D-A-E-A-L-D-A-M-A-A-A-V-I-V-E-R-W-L-A-A-P-D-Q-A-T-L-L-P"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-R-G-I-N-K-V-I-L-V-G-N-L-G-N-D-P-D-T-K-Y-T-Q-A-G-M-A-I-T-R-V-S-L-A-T-T-S-M-R-K-D-R-D-G-N-N-Q-E-R-T-E-W-H-R-V-V-F-F-G-K-L-G-E-I-A-G-E-Y-L-R-K-G-S-Q-V-Y-V-E-G-E-L-R-Y-D-K-Y-T-G-Q-D-G-V-E-K-Y-S-T-D-I-V-A-N-E-M-Q-M-L-G-G-R-G-E-G-G-G-G-G-M-G-G-D-R-P-Q-R-S-A-P-R-Q-Q-G-G-G-G-G-Q-G-G-G-G-Y-G-G-G-G-G-G-G-G-Q-D-Y-A-P-R-R-Q-Q-P-A-Q-Q-Q-S-A-P-P-M-D-D-F-A-D-D-D-I-P-F"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-C-R-L-I-A-T-G-E-R-A-P-S-W-V-A-Q-G-F-A-E-Y-Q-K-R-L-S-H-W-M-P-L-E-L-V-E-I-E-P-G-M-R-G-K-G-R-D-A-Q-R-A-T-D-D-E-G-R-R-V-L-A-A-L-P-K-N-A-Y-V-V-A-L-D-V-P-G-R-P-L-S-S-E-Q-L-A-Q-R-M-E-H-W-R-G-Q-G-R-D-L-A-F-L-I-G-G-P-E-G-H-A-A-E-V-L-K-S-A-S-E-S-W-S-I-G-P-L-T-L-P-H-M-L-V-R-L-I-V-A-E-Q-L-Y-R-A-A-A-M-L-A-N-H-P-Y-H-R-A"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-K-K-S-L-N-E-T-S-P-V-A-R-F-E-Q-S-L-E-E-L-E-Q-L-V-Q-K-M-E-V-G-D-L-S-L-E-Q-S-L-T-A-Y-E-R-G-I-G-L-Y-R-D-C-Q-Q-A-L-E-Q-A-E-L-R-V-R-L-L-T-D-P-A-R-P-E-L-A-E-A-F-E-P-P-S-L-D-G"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-S-R-W-R-P-P-A-E-K-S-T-A-L-I-T-P-E-G-H-A-R-L-K-A-E-L-D-D-L-W-R-V-R-R-P-E-V-V-R-A-L-A-A-A-A-A-E-G-D-R-S-E-N-A-E-Y-T-Y-R-K-K-Q-L-G-E-I-D-R-R-V-R-Y-L-S-K-R-L-E-A-L-R-V-V-D-T-A-P-T-D-A-N-A-V-F-F-G-A-Q-V-E-L-E-D-A-G-S-G-E-L-L-R-Y-R-I-V-G-P-D-E-T-D-A-G-R-G-W-I-S-I-D-S-P-L-A-R-A-L-L-K-K-R-V-D-D-E-F-D-A-H-L-P-A-G-K-H-T-F-V-V-V-S-V-D-Y-A-S-L"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-E-K-A-T-E-I-A-N-L-L-S-P-T-V-E-S-L-G-L-E-L-L-G-V-E-Y-L-P-A-P-G-G-A-T-L-R-L-Y-I-D-V-P-L-A-E-Q-P-E-R-V-I-N-V-D-D-C-E-R-V-S-R-E-V-S-A-Q-L-D-V-E-D-P-I-S-G-N-Y-T-L-E-V-S-S-P-G-V-D-R-P-L-F-T-L-E-Q-F-A-R-H-T-G-E-S-A-K-I-V-L-K-L-A-Q-D-G-R-R-R-F-Q-G-Q-I-L-R-I-D-A-E-A-A-A-V-V-F-A-V-D-G-K-D-V-Q-I-G-Y-D-N-I-D-K-A-R-I-V-P-D-W-V-A-L-G-L-A-P-Q-K-P-N-K-P-G-P-K-K-P-G-H-E-K-K-K-P-S-N-E-S-A-A-G-K-P-R-A-E"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-T-K-S-F-H-R-T-D-R-V-S-A-Q-V-R-R-D-L-G-T-I-V-H-A-A-V-R-D-N-G-L-P-S-V-S-V-S-D-V-E-I-S-R-D-L-A-H-A-K-V-F-V-T-A-L-Q-Q-E-R-S-A-E-A-V-K-G-L-K-E-I-A-G-Q-L-R-T-Q-L-A-R-A-M-K-L-R-H-V-P-E-L-H-F-H-Y-D-D-S-V-D-R-G-E-R-I-D-N-L-L-R-D-L-D-D-V-G-P-E-A-T-S-S-D-E-D-A-E-Q-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-V-D-T-Q-K-V-I-E-D-N-K-R-S-A-Q-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-R-I-E-L-L-T-G-H-F-K-T-H-K-K-D-H-H-S-R-R-G-L-L-Q-M-V-N-R-R-R-S-L-L-D-Y-L-K-K-K-D-N-E-R-Y-K-S-L-I-E-K-L-G-L-R-R"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-P-L-G-D-C-N-I-S-T-P-D-N-K-Q-N-R-K-N-Q-E-I-R-V-P-R-V-R-V-I-G-S-D-G-E-M-V-G-V-L-S-R-D-E-A-L-A-K-A-E-E-E-G-L-D-L-V-E-I-Q-P-Q-A-D-P-P-V-C-K-I-M-D-F-G-K-F-K-F-E-Q-Q-K-K-A-N-E-A-K-K-K-T-K-Q-V-E-I-K-E-L-K-F-R-P-V-T-D-E-G-D-Y-Q-I-K-L-R-N-M-R-R-F-L-E-E-G-D-K-V-K-V-N-I-R-F-R-G-R-E-M-S-H-Q-E-L-G-R-E-M-A-A-R-I-E-A-D-L-G-D-D-I-V-I-E-S-R-P-R-L-E-G-R-Q-M-V-M-M-I-A-P-K-K-K-V"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-Q-A-R-R-R-H-K-K-I-L-T-L-A-K-G-Y-Y-N-A-R-R-K-V-F-R-V-A-K-Q-A-V-I-K-A-Q-Q-Y-A-Y-I-G-R-K-Q-K-K-R-N-F-R-S-L-W-I-T-R-I-N-A-A-A-R-I-N-G-L-S-Y-S-R-F-M-N-G-L-L-K-A-G-I-T-L-D-R-K-V-L-A-D-I-A-V-H-D-A-A-G-F-A-A-L-A-E-K-A-K-G-A-L-A-A"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-K-G-P-V-R-L-D-V-A-V-S-Y-A-L-P-R-A-G-L-P-S-A-V-S-F-R-K-W-V-A-A-A-L-K-G-R-I-R-E-A-D-L-A-V-R-V-V-D-E-K-E-G-C-S-L-N-H-H-Y-R-G-K-D-Y-A-T-N-V-L-S-F-P-A-E-L-P-E-G-L-P-K-G-I-K-M-P-L-L-G-D-L-V-I-C-A-P-V-V-A-R-E-A-A-E-Q-G-K-S-L-A-A-H-Y-A-H-L-T-V-H-G-T-L-H-L-L-G-W-D-H-E-D-D-K-E-A-E-A-M-E-Q-L-E-R-E-I-L-A-D-L-G-I-D-D-P-Y-A-G-E-H"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-D-C-S-R-C-A-G-T-N-T-S-G-P-N-H-W-P-E-R-I-R-D-I-V-D-F-P-K-P-G-I-V-F-K-D-I-T-P-L-L-S-D-G-P-D-F-A-S-A-L-D-E-M-A-Q-P-W-R-T-T-P-L-D-A-V-L-G-I-E-A-R-G-F-I-L-G-A-A-L-A-R-E-L-R-T-G-F-V-P-V-R-K-P-G-K-L-P-G-R-T-L-I-Q-E-Y-A-L-E-Y-G-T-D-R-I-E-M-H-E-D-A-L-P-R-G-A-R-V-L-I-V-D-D-V-L-A-T-G-G-T-L-R-A-A-L-G-L-A-A-Q-L-E-L-E-V-V-G-A-A-V-L-V-E-L-Q-G-L-Q-G-R-Q-K-W-A-N-D-V-P-L-L-A-T-L-S-Y"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-T-V-G-M-N-D-V-K-N-G-M-K-I-L-V-N-N-E-P-A-V-I-T-E-T-E-Y-V-K-P-G-K-G-Q-A-F-T-R-M-K-Y-R-F-I-K-S-G-R-V-V-E-M-T-M-K-A-T-D-D-V-E-V-A-D-V-V-D-T-D-M-R-Y-L-Y-S-D-G-E-Y-W-H-F-M-D-P-D-T-F-E-Q-V-Q-T-D-K-A-G-M-G-G-A-D-K-W-L-K-G-E-E-D-C-I-V-T-L-W-N-G-T-P-I-W-V-Q-P-P-N-F-V-E-L-K-I-T-E-T-D-P-G-V-R-G-D-T-S-G-G-G-G-K-P-A-T-L-E-T-G-A-V-V-R-V-P-L-F-V-N-Q-D-E-I-I-K-V-D-T-R-S-G-E-Y-S-A-R-V-K"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-I-L-A-R-R-Q-A-H-L-K-S-D-D-V-D-L-A-V-K-S-L-L-E-M-M-G-Q-A-L-S-D-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-P-P-R-L-G-R-N-P-K-T-G-E-S-V-A-L-P-G-K-H-V-P-H-F-K-P-G-K-E-L-R-E-R-V-S-S-V-V-P-V-D-V-A-D-T-A-D"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-Q-I-S-D-K-A-Q-T-Y-F-R-K-L-I-E-R-E-G-V-P-G-M-G-V-R-L-S-A-V-D-A-G-T-P-R-A-D-A-R-L-E-F-A-E-P-A-D-L-S-G-D-E-W-A-I-D-C-D-G-F-T-L-Y-V-V-A-A-S-V-P-W-M-D-G-A-E-I-D-Y-V-T-Q-S-T-G-N-Q-Q-L-T-I-K-A-P-K-I-K-G-E-A-P-A-E-S-A-S-M-V-E-R-V-R-W-V-V-E-N-E-I-N-P-Q-L-A-S-H-G-G-R-V-A-V-Q-E-V-S-A-E-G-V-V-L-L-R-F-G-G-G-C-H-G-C-G-M-A-D-V-T-L-K-Q-G-I-E-K-T-L-M-G-R-V-P-G-V-T-A-V-R-D-A-T-D-H-A-T-G-D-A-P-Y-I-P-R-D-S-A-A"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-E-N-L-A-G-N-D-R-L-I-W-I-D-L-E-M-T-G-L-D-T-D-R-D-S-I-I-E-I-A-T-I-V-T-D-A-Q-L-N-V-L-A-E-G-P-E-L-A-I-A-H-P-L-E-T-L-E-A-M-D-E-W-N-R-N-Q-H-R-R-S-G-L-W-Q-R-V-I-D-S-Q-V-T-H-A-Q-A-E-A-Q-T-V-A-F-L-S-E-W-I-R-A-G-A-S-P-M-C-G-N-S-I-C-Q-D-R-R-F-L-H-R-Q-M-S-R-L-E-R-Y-F-H-Y-R-N-L-D-V-S-T-I-K-E-L-A-R-R-W-A-P-T-V-A-N-G-F-A-K-S-S-A-H-T-A-L-S-D-V-R-D-S-I-D-E-L-R-H-Y-R-Q-F-M-G-A-L-G-G-D-T-A-A-G-V-E-N"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-A-P-V-W-W-Q-Q-L-L-L-A-M-T-G-G-A-L-G-S-G-L-R-F-A-I-G-A-S-L-I-Q-R-F-G-N-V-F-P-W-G-T-L-T-V-N-L-L-G-S-F-V-A-G-V-L-L-V-W-L-D-A-R-G-P-S-S-W-P-L-R-A-L-L-I-V-G-V-I-G-G-L-T-T-F-S-S-L-M-M-E-C-L-V-F-A-R-T-D-R-S-T-M-I-G-I-Y-L-A-V-T-L-L-A-G-L-A-L-V-F-A-G-A-R-T-G-Q-W-L-V-T-R"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-S-I-E-F-E-G-S-V-S-E-T-L-P-N-T-T-F-R-V-K-L-E-N-G-H-E-I-I-A-H-I-S-G-R-M-R-K-N-Y-I-R-I-L-T-G-D-R-V-K-V-E-M-T-P-Y-D-L-T-K-G-R-I-T-Y-R-M-K"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-P-R-N-T-S-H-E-H-D-H-G-L-M-V-E-A-S-K-P-E-V-A-P-P-P-R-Y-Q-V-L-L-L-N-D-D-Y-T-P-M-D-F-V-V-T-V-L-E-Q-F-F-N-L-N-L-E-Q-A-T-Q-I-M-L-H-V-H-T-R-G-R-G-V-C-G-V-Y-S-R-E-V-A-E-S-K-V-A-Q-V-N-E-F-S-R-M-N-Q-H-P-L-L-C-T-M-E-Q-A"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-S-T-A-V-Q-V-D-D-V-M-R-Y-R-D-S-R-F-Q-T-I-A-A-K-L-L-P-T-Q-Y-L-V-V-D-D-D-T-A-L-T-T-T-L-G-S-C-V-A-A-C-L-R-D-P-V-L-K-I-G-G-M-N-H-F-L-L-P-E-G-Q-V-G-D-G-A-P-T-R-Y-G-S-Y-A-M-E-L-L-I-N-D-M-L-K-R-G-A-H-R-K-R-I-E-A-K-V-F-G-G-A-N-V-L-K-G-F-T-S-N-P-V-G-T-R-N-A-E-F-V-R-Q-Y-L-Q-A-E-H-I-P-I-I-A-E-D-L-C-G-I-H-P-R-K-V-W-F-F-A-T-T-G-R-V-V-V-Q-R-L-P-H-A-H-E-A-E-V-A-A-T-E-S-A-V-R-A-R-L-S-K-A-P-V-T-G-G-V-E-L-F-E"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-R-A-P-M-T-S-K-G-A-Q-R-L-R-E-E-L-E-H-L-K-S-V-K-R-P-E-V-I-N-A-I-A-E-A-R-A-H-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-Q-Q-S-F-I-E-G-R-I-K-Q-L-E-S-E-L-S-H-A-E-I-I-D-I-T-K-L-S-A-G-T-K-I-V-F-G-A-T-V-T-L-A-D-T-E-T-D-E-E-K-R-Y-Q-I-V-G-D-L-E-A-D-I-K-M-G-L-I-A-I-S-S-P-L-A-R-A-L-I-G-K-L-E-G-D-S-V-T-I-D-A-P-A-G-Q-R-E-Y-E-V-V-S-V-A-Y-L-D"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-M-I-G-D-S-V-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-I-T-A-P-K-D-V-A-V-H-R-E-E-I-Y-Q-R-I-Q-R-G-D-E-P-V-A-S-G-A-H-H-G-D-D-S-S-N"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-V-P-V-S-V-Y-L-V-N-G-I-K-L-Q-G-T-I-E-S-F-D-Q-F-V-V-L-L-R-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-N-V-R-V-G-P-G-G-G-Y-V-Q-S-N-E-G-N-Q-A-E-D-D-D-V-E-Q"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-N-W-R-W-L-L-L-V-L-A-V-L-L-A-W-L-Q-Y-R-F-W-F-G-P-G-N-S-G-E-V-M-M-L-E-A-Q-V-A-H-Q-T-Q-D-N-E-G-L-R-Q-R-N-Q-A-L-A-A-E-V-K-D-L-K-D-G-E-A-A-I-E-E-R-A-R-S-E-L-G-M-I-K-P-G-E-T-F-Y-R-V-V-E-D-A-P-L-P-A-P-A-S-A-E-A-S-A-P-A-Q-Q-A-P-E-P-V-D-P-V-D-H-P"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-D-L-I-L-L-Q-K-V-T-N-L-G-N-L-G-D-K-V-S-V-K-P-G-Y-G-R-N-F-L-V-P-Q-G-K-A-V-P-A-T-A-A-N-V-E-A-F-E-T-K-R-A-E-Y-E-A-K-A-N-S-I-L-A-E-A-Q-S-R-A-T-K-F-E-G-A-S-V-T-I-G-A-H-A-S-T-E-G-K-L-Y-G-S-V-G-P-R-D-I-A-E-A-F-T-A-A-G-L-P-L-E-K-S-E-V-I-L-G-E-G-A-F-R-N-V-G-E-Y-D-V-V-L-H-L-H-A-D-V-E-T-T-V-K-V-I-V-E-S-D-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-K-F-F-R-R-R-K-F-C-K-F-T-A-E-G-V-K-E-I-D-Y-K-D-L-N-T-L-R-Q-Y-L-T-E-N-G-K-I-V-P-S-R-V-T-G-T-K-S-K-Y-Q-R-Q-L-A-T-A-V-K-R-A-R-F-L-A-L-I-P-Y-T-D-N-H-D-V"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-R-H-Y-E-V-V-F-L-V-H-P-D-Q-S-E-Q-V-P-A-M-I-E-R-Y-K-S-L-I-E-G-G-N-G-T-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-Q-N-L-V-K-A-H-Y-V-L-L-N-I-E-V-D-Q-A-V-L-S-E-L-V-E-S-F-R-F-N-D-A-V-L-R-H-L-V-V-K-R-D-G-A-D-T-E-Q-S-L-I-M-K-S-K-D-E-K-G-D-K-P-E-R-S-E-R-R-R-R-D-D-E-E-G-E-A-P-A-A-N-D-N-D-G-D-N-A-E-A-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-Q-D-H-P-E-F-D-S-E-D-L-S-Q-N-P-P-E-T-D-P-L-K-A-E-I-E-S-L-R-S-E-I-A-L-V-K-A-D-A-L-R-E-R-A-D-L-E-N-Q-R-K-R-I-A-R-D-V-E-N-A-R-K-F-A-N-E-K-L-L-G-E-L-L-P-V-F-D-S-L-D-A-G-L-T-A-A-G-T-E-P-S-P-L-R-D-G-L-D-M-T-Y-K-Q-L-L-K-V-A-A-D-N-G-L-T-L-L-D-P-V-G-Q-P-F-N-P-D-Q-H-Q-A-I-S-Q-G-E-A-E-G-V-A-P-G-H-V-V-Q-V-F-Q-K-G-Y-L-L-N-D-R-L-L-R-P-A-L-V-V-V-A-K-H-D"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-K-K-Q-T-K-D-K-A-N-G-A-K-A-T-K-T-I-A-L-N-K-R-A-R-H-E-Y-H-L-E-E-R-Y-E-A-G-L-A-L-Q-G-W-E-V-K-A-I-R-A-G-R-A-N-I-V-D-G-Y-A-Y-V-R-S-G-E-I-Y-L-I-G-A-Q-I-T-P-L-I-Q-A-S-T-H-T-V-P-V-E-R-R-D-R-K-L-L-L-H-R-A-E-I-D-K-V-L-S-R-V-E-R-E-G-Y-T-L-V-P-T-A-L-Y-W-S-S-N-K-V-K-L-E-I-A-L-A-K-G-K-Q-N-H-D-K-R-D-A-A-K-D-R-D-W-Q-R-D-K-Q-R-V-M-R-R-H-N-R-D-A"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-T-Q-I-K-Q-D-A-Q-T-R-M-T-K-S-I-D-A-L-R-H-S-L-T-T-I-R-T-G-R-A-S-P-A-L-L-D-G-I-K-V-K-A-Y-G-A-D-T-P-L-N-Q-V-A-S-I-S-V-S-E-G-R-S-L-V-I-S-L-F-D-K-G-M-I-K-D-V-E-K-A-I-Y-A-S-D-L-G-L-T-P-T-V-V-G-T-V-I-R-L-N-L-P-P-L-T-E-E-R-R-K-E-L-S-K-S-V-H-G-E-G-E-D-S-K-V-A-I-R-N-I-R-R-D-A-N-Q-Q-V-K-D-L-L-K-D-K-A-V-T-E-D-E-A-R-S-A-E-D-D-I-Q-K-L-T-D-K-A-I-K-D-V-D-E-V-V-K-G-K-E-Q-E-L-M-T-V"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-K-L-N-K-T-I-L-A-D-F-E-A-A-Q-I-Q-R-K-L-P-E-F-N-Q-G-D-T-V-V-V-N-V-K-V-K-E-G-N-R-E-R-V-Q-A-Y-E-G-V-V-I-G-T-K-N-A-G-L-N-S-S-F-T-V-R-K-I-S-H-G-F-G-V-E-R-V-F-Q-T-H-S-A-I-I-D-S-V-E-V-K-R-R-G-K-V-R-A-G-K-L-Y-Y-L-R-G-L-E-G-K-A-A-R-I-K-E-D-L-A-A-A-A-Q-A-K-A-A-R-Q-A-A-A-K-A-E"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-Q-N-E-R-R-I-L-L-G-R-I-V-G-A-F-G-V-K-G-E-L-K-L-E-S-W-T-E-P-R-T-A-I-F-R-Y-Q-P-W-I-V-R-S-P-S-G-Q-E-S-V-V-S-G-V-R-G-R-D-Q-G-K-N-L-I-A-V-F-P-G-V-T-D-R-D-T-V-E-A-M-H-G-T-E-I-Y-V-A-R-S-A-L-P-P-P-K-P-D-E-Y-Y-W-V-D-L-E-E-L-Q-V-E-T-V-E-G-V-K-L-G-T-V-S-H-L-F-S-T-G-S-N-D-V-V-V-V-R-G-D-R-E-R-M-I-P-F-V-F-P-D-F-V-K-S-V-D-F-E-A-N-L-I-V-V-D-W-D-P-D-F"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-R-A-K-Q-T-I-V-R-N-E-R-N-T-G-Q-R-S-M-L-R-T-A-V-K-K-V-I-K-A-L-D-A-N-D-A-A-G-A-E-A-A-F-A-V-A-Q-P-I-L-D-R-F-S-A-R-G-L-I-H-K-N-K-A-A-R-H-K-S-R-L-T-A-R-I-K-A-I-K-A-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-L-V-T-G-G-K-Q-Y-R-V-A-Q-G-E-T-L-R-V-E-K-L-E-V-E-A-G-N-E-I-K-F-D-T-I-L-M-L-G-D-S-D-G-I-K-L-G-D-A-L-K-G-A-S-V-T-A-K-V-V-A-H-G-R-A-D-K-V-R-I-I-K-F-R-R-R-K-H-H-M-K-R-Q-G-H-R-Q-H-Y-T-E-I-E-I-T-G-I-A-G-G-D-K-K"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-G-L-L-D-F-L-K-S-K-K-N-T-A-E-T-A-K-N-R-L-Q-I-I-I-A-Q-E-R-N-H-R-G-G-P-D-Y-L-P-L-M-Q-R-E-L-L-E-V-I-K-K-Y-V-N-I-D-A-D-A-V-R-V-D-L-V-K-D-G-E-H-D-V-L-D-I-S-V-A-L-P-E-D-G-D-K"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-P-R-L-I-L-A-S-T-S-V-Y-R-R-A-L-L-G-R-L-Q-L-D-F-D-T-V-R-P-E-V-D-E-Q-A-R-P-G-E-S-P-S-A-L-A-S-R-L-A-V-E-K-A-A-T-V-A-A-R-F-P-D-A-W-V-I-G-S-D-Q-V-A-D-L-D-G-Q-A-L-G-K-P-G-T-H-E-R-A-R-M-Q-L-T-A-M-S-G-Q-T-V-R-F-H-T-A-V-S-L-V-G-P-E-R-Q-L-H-A-L-D-L-T-E-V-Q-L-R-A-L-T-V-V-E-I-E-R-Y-L-D-A-E-P-A-L-D-C-A-G-S-F-K-C-E-G-L-G-I-S-L-F-D-A-I-R-S-E-D-P-T-A-L-V-G-L-P-M-I-A-L-A-R-L-L-R-Q-A-G-F-Q-I-P"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-T-L-L-E-Q-L-I-E-A-F-R-V-L-P-G-V-G-Q-K-S-A-Q-R-M-A-Y-H-V-L-E-R-E-R-E-G-G-R-R-L-A-A-A-L-G-S-A-V-E-K-V-G-H-C-V-Q-C-R-D-F-T-E-S-E-I-C-T-I-C-A-S-S-S-R-D-R-Q-Q-L-C-V-V-E-S-P-A-D-R-L-A-I-E-H-A-T-G-Y-R-G-L-Y-F-I-L-Q-G-R-L-S-P-L-D-G-I-G-P-R-E-L-G-L-D-R-L-S-E-R-L-A-A-G-E-V-T-E-M-I-I-A-T-N-A-T-V-E-G-E-A-T-A-H-Y-L-A-Q-L-A-R-Q-H-A-V-R-P-S-R-L-A-Q-G-M-P-L-G-G-E-L-E-Y-V-D-R-G-T-L-S-H-A-F-G-T-R-S-E-V-L"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-R-G-N-I-A-Q-L-M-Q-Q-A-Q-K-M-Q-E-N-L-Q-R-A-Q-E-E-L-A-K-L-E-V-T-G-T-A-G-G-G-M-V-S-V-T-L-T-G-A-K-E-C-R-K-V-R-I-D-P-S-I-L-S-D-Q-E-M-A-E-D-L-I-A-A-A-F-N-D-A-S-N-K-I-D-A-E-S-K-D-R-M-G-S-A-T-A-G-M-Q-L-P-P-G-M-K-L-P-F"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-N-P-F-R-W-S-F-R-A-Q-F-L-L-G-F-L-A-C-A-G-L-L-A-Y-A-I-Y-V-Q-L-H-L-G-L-E-P-C-P-L-C-I-F-Q-R-I-A-F-A-A-L-A-V-F-F-L-L-G-A-L-H-G-P-R-A-A-A-G-R-K-V-Y-G-V-L-S-F-I-A-A-G-V-G-M-G-I-A-A-R-H-V-W-V-Q-I-R-P-K-D-M-M-S-S-C-G-P-P-L-S-F-L-S-E-T-M-G-P-F-E-V-F-R-T-V-L-T-G-T-G-D-C-G-N-I-D-W-R-F-L-G-L-S-M-P-M-W-S-M-V-W-F-V-G-L-A-L-W-A-L-Y-A-G-F-K-V-R-R-S-S-V-H-H"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-L-R-L-N-D-L-K-P-A-D-G-A-R-T-E-R-T-R-V-G-R-G-I-G-S-G-L-G-K-T-A-G-R-G-H-K-G-S-F-A-R-K-G-G-G-K-I-K-A-G-F-E-G-G-Q-T-P-M-Q-R-R-L-P-K-I-G-F-R-S-K-M-A-R-D-T-A-E-V-L-S-Y-Q-L-D-K-L-D-A-G-D-V-D-F-A-A-L-R-A-A-N-L-V-P-S-R-A-K-K-A-K-I-V-L-K-G-E-L-S-K-K-F-V-L-K-G-V-A-A-T-A-G-A-K-A-A-I-E-A-A-G-G-S-V-E-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-I-N-K-N-I-A-R-L-R-R-A-K-S-T-R-A-H-I-R-E-L-G-V-A-R-L-S-V-L-R-T-G-Q-H-L-Y-A-Q-V-F-T-A-D-G-S-K-V-I-A-A-A-N-T-L-Q-A-D-V-K-D-G-L-K-N-G-K-N-S-D-A-A-A-K-V-G-K-L-I-A-E-R-A-K-A-A-G-I-E-K-V-A-F-D-R-S-G-Y-R-Y-H-G-R-I-K-A-L-A-D-A-A-R-E-G-G-L-Q-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-K-P-V-S-L-P-K-G-V-E-L-N-V-Q-P-G-L-V-S-V-K-G-P-K-G-T-L-T-L-P-K-P-A-G-V-E-I-A-I-D-G-G-V-A-T-L-S-A-N-D-P-S-Q-I-A-L-T-G-T-V-R-A-I-L-A-N-M-V-K-G-V-S-E-G-F-E-R-K-L-E-L-V-G-V-G-Y-R-A-A-M-Q-G-K-D-L-S-L-A-L-G-F-S-H-P-L-V-F-V-A-P-E-G-I-T-L-S-T-P-T-Q-T-E-I-V-V-Q-G-A-D-K-Q-R-V-G-E-V-A-A-K-I-R-G-F-R-P-P-E-P-Y-K-G-K-G-V-K-Y-A-G-E-V-I-I-R-K-E-A-K-K-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-T-D-P-I-A-D-L-L-V-R-I-K-N-A-A-A-V-G-K-Q-T-V-K-L-P-S-S-K-I-K-V-A-I-A-Q-V-L-K-D-E-G-Y-I-T-D-L-R-V-T-Q-A-E-N-N-K-A-E-L-E-I-V-L-K-Y-F-E-G-R-P-V-I-E-T-L-K-R-F-S-R-S-G-L-R-Q-Y-R-G-K-T-E-L-P-K-V-L-G-G-L-G-I-A-I-I-S-T-S-K-G-I-M-T-D-A-Q-A-R-E-A-G-V-G-G-E-V-L-C-F-V-A"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-T-R-L-E-K-F-Y-K-D-N-V-V-P-A-L-M-K-E-F-G-Y-T-N-P-M-E-V-P-K-L-V-K-V-T-L-N-M-G-V-G-E-A-A-T-N-K-K-I-L-E-N-A-V-A-D-M-A-K-I-S-G-Q-K-P-V-V-T-K-S-R-V-S-V-A-S-F-K-I-R-D-G-W-P-I-G-C-K-T-T-L-R-R-A-K-M-Y-E-F-L-D-R-L-I-N-I-S-L-P-R-V-R-D-F-R-G-V-S-G-R-S-F-D-G-R-G-N-F-N-M-G-V-K-E-Q-I-I-F-P-E-I-D-F-D-A-V-D-A-I-R-G-M-D-I-A-I-T-T-T-A-K-T-D-A-E-A-K-A-L-L-A-A-F-K-F-P-F-R-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-N-R-I-K-K-G-D-Q-V-V-I-N-T-G-K-D-K-G-K-Q-G-E-V-V-R-V-D-G-D-R-V-I-V-S-N-A-N-V-I-K-R-H-T-K-P-N-P-Q-A-G-V-A-G-G-V-V-E-R-E-A-S-I-H-I-S-N-V-N-I-V-N-P-A-T-G-K-G-E-R-V-G-F-K-V-L-E-D-G-R-K-L-R-V-F-R-S-S-G-E-A-L-D-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-D-N-N-E-K-Q-T-L-R-T-V-E-G-R-V-V-S-N-K-M-D-K-T-V-T-V-L-V-E-R-Q-V-K-H-A-L-Y-G-K-Y-I-K-R-S-T-K-L-H-A-H-D-A-D-N-A-C-N-E-G-D-V-V-R-V-T-E-I-A-P-M-S-K-T-K-N-W-R-V-V-E-I-V-T-R-S-A-E"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-Y-R-K-M-H-K-G-R-N-D-G-L-A-W-S-G-N-A-V-S-F-G-E-Y-G-L-K-A-T-A-H-G-Q-L-T-A-R-Q-I-E-A-A-R-R-T-I-S-R-H-V-K-K-G-G-K-M-W-I-R-V-F-P-D-K-P-I-T-K-K-P-I-E-V-R-M-G-S-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-R-M-I-Y-E-I-E-G-I-P-E-E-T-A-R-E-A-F-R-L-A-A-A-K-L-S-V-T-T-T-F-V-T-R-T-V-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-V-D-H-H-L-A-K-K-V-E-S-A-A-G-S-K-K-P-I-K-T-W-S-R-R-S-M-I-L-P-E-M-V-G-I-T-I-A-V-H-N-G-K-N-H-I-P-V-L-V-N-E-N-M-V-G-H-K-L-G-E-F-A-V-T-R-T-F-K-G-H-G-G-D-K-K-S-G-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-S-N-E-K-I-F-S-V-L-R-A-P-R-V-S-E-K-T-A-R-L-Q-E-I-S-N-Q-Y-V-F-E-V-S-N-E-A-T-K-A-D-V-K-A-A-V-E-Q-L-F-D-V-K-V-K-A-V-N-V-V-N-V-K-G-K-S-K-S-F-R-N-R-A-G-N-R-G-N-W-R-K-A-Y-V-R-L-V-D-G-Q-S-I-D-V-T-A-K-A"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-E-Q-K-I-R-I-R-L-K-A-F-D-H-R-L-I-D-R-S-A-S-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-K-I-E-R-Y-T-I-L-V-S-P-H-A-D-K-D-A-R-D-Q-Y-E-T-R-T-H-K-R-V-L-D-I-V-D-P-N-D-K-T-V-D-A-L-M-K-L-E-L-A-A-G-V-D-V-Q-I-K-L-T"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-G-S-T-P-Q-R-T-V-L-P-D-P-K-H-G-S-E-T-I-A-R-F-I-N-M-V-M-Q-S-G-K-K-S-V-A-E-K-I-V-Y-G-A-M-D-V-I-G-E-K-N-P-N-A-I-E-L-V-Q-K-A-L-D-N-V-A-P-A-V-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-S-S-R-R-M-A-L-A-M-R-W-L-I-D-S-A-R-K-R-G-E-N-T-M-P-R-K-L-A-A-E-L-L-D-A-S-E-S-R-G-G-A-I-K-K-R-E-E-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-L-T-N-E-Q-I-V-D-A-I-A-E-K-S-L-M-E-V-M-E-L-V-K-A-I-E-E-K-F-G-V-S-A-A-A-P-V-A-A-A-A-A-G-P-A-A-V-V-E-E-Q-T-E-F-N-V-V-L-T-N-C-G-T-N-K-V-G-V-I-K-A-V-R-A-V-T-G-L-G-L-K-E-A-K-D-L-T-E-A-G-G-M-L-K-E-G-A-S-K-D-E-A-E-K-I-K-K-E-L-T-E-A-G-A-T-V-E-I-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-S-Q-K-Q-E-V-V-A-E-L-A-D-I-A-A-K-A-H-S-L-I-A-A-E-Y-A-G-T-T-V-S-Q-M-T-A-M-R-K-Q-A-R-E-T-G-V-F-L-K-V-V-K-N-T-L-A-A-R-A-V-E-G-T-D-F-A-V-A-A-D-K-L-V-G-P-L-L-Y-A-F-S-M-E-E-P-G-A-A-G-R-L-I-K-E-F-A-K-S-N-D-K-L-Q-A-K-V-V-S-I-G-G-E-L-F-P-A-G-H-V-D-V-L-A-S-L-P-T-R-D-Q-A-L-A-M-L-A-R-V-L-S-E-P-A-A-M-F-A-R-A-V-K-A-V-G-D-K-Q-G-G-G-D-E-A-A-A-P-V-A-E-T-A-E-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-T-A-F-I-K-L-Q-V-K-A-G-Q-A-N-P-A-P-P-V-G-P-A-L-G-Q-R-G-L-N-I-M-E-F-C-K-A-F-N-A-A-T-S-K-L-E-P-G-L-P-T-P-V-I-I-T-A-Y-S-D-R-T-F-T-F-V-T-K-S-T-P-A-S-V-L-L-K-K-A-A-G-V-S-S-G-S-K-R-P-N-T-D-K-V-G-K-V-T-R-K-Q-L-E-E-I-A-K-V-K-E-A-D-L-T-A-A-E-L-E-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-T-V-E-G"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-A-L-R-L-I-V-G-L-G-N-P-G-P-E-H-A-Q-T-R-H-N-A-G-F-R-F-V-D-A-L-I-E-R-S-G-A-R-W-A-L-D-S-K-L-F-G-E-T-A-K-V-E-V-A-G-Q-P-V-W-L-L-K-P-A-T-F-M-N-L-S-G-K-S-I-T-A-A-L-R-F-W-K-I-E-P-E-H-L-L-V-A-H-D-E-L-D-L-A-P-G-T-A-R-L-K-F-D-G-G-H-G-G-Q-N-G-L-R-D-T-I-R-L-L-G-H-G-K-F-H-R-L-R-V-G-I-G-H-P-G-H-K-D-R-V-V-P-W-V-L-G-R-A-G-R-E-D-D-A-A-I-G-A-A-V-D-A-A-I-D-V-L-P-L-A-M-E-G-N-F-N-E-A-M-K-R-L-H-T-E-K-K"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-K-P-G-G-H-S-R-H-G-R-R-D-G-I-D-P-V-L-R-S-R-A-R-R-R-A-L-Q-A-V-Y-A-W-Q-I-S-G-G-F-A-K-Q-V-I-A-Q-F-A-H-E-Q-A-H-E-V-A-D-L-A-Y-F-E-N-L-V-E-G-V-L-S-N-R-A-E-L-D-T-A-L-T-P-Y-L-D-R-S-V-E-E-V-D-A-I-E-R-A-V-L-R-L-A-A-Y-E-L-L-Y-R-Q-D-V-P-Y-R-V-V-I-N-E-A-I-E-T-A-K-R-F-G-S-E-H-G-H-T-Y-V-N-G-V-L-D-R-A-A-V-E-W-R-K-V-E-S-G-A-S-G-A"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-Q-H-N-D-T-R-V-I-D-S-R-V-S-E-D-G-T-T-I-R-R-R-R-E-C-E-A-C-G-E-R-F-S-T-L-E-T-I-E-L-K-L-P-T-V-V-K-S-D-G-G-R-E-A-F-D-A-R-K-L-R-T-S-F-D-R-A-L-Q-K-R-P-V-A-E-E-Q-I-E-A-A-V-R-A-V-V-H-Q-L-R-M-S-G-E-R-E-V-G-S-L-R-V-G-E-Y-V-M-V-E-L-R-K-L-D-H-V-G-Y-V-R-F-A-S-V-Y-R-S-F-Q-D-V-A-D-F-R-E-E-I-E-K-L-E-R-E-L-P-V-G-S-E-Q-L-P-L-L-E-A-A-L-E-R-A-G-K-P-G-K-R"} +{"text": "### FUNCTION Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'--3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism ### SEQUENCE -M-E-T-L-R-Y-R-F-D-G-Q-R-G-A-R-A-G-L-E-H-A-L-V-G-V-V-A-S-G-N-L-E-V-L-V-E-R-V-P-L-E-G-A-M-E-I-D-I-L-T-A-A-R-G-F-G-A-I-W-Q-A-V-L-D-D-F-A-A-R-H-P-L-R-D-V-R-I-S-I-N-D-V-G-A-T-P-A-V-V-S-L-R-L-E-Q-A-L-D-V-L-Q-G-A-D-A"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-T-L-V-S-L-P-T-A-A-P-A-P-D-Y-Q-S-I-D-R-P-L-N-F-S-V-A-A-A-A-K-V-R-E-L-I-Q-E-E-G-N-A-D-L-A-L-R-V-Y-I-Q-G-G-G-C-S-G-F-Q-Y-G-F-E-F-D-E-N-R-A-E-D-D-L-A-V-A-T-D-G-V-T-L-L-V-D-P-L-S-L-Q-Y-L-M-G-A-E-V-D-Y-T-E-S-L-T-G-A-Q-F-V-I-R-N-P-N-A-K-T-T-C-G-C-G-S-S-F-S-V"} +{"text": "### FUNCTION Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA ### SEQUENCE -M-L-V-L-L-N-K-P-Y-G-V-L-S-Q-F-S-D-R-S-Q-P-P-K-R-T-L-A-E-F-G-L-P-P-D-V-Y-A-A-G-R-L-D-H-D-S-E-G-L-L-V-L-T-D-D-G-A-L-A-H-R-L-T-D-P-R-H-K-Q-P-K-T-Y-W-V-Q-V-E-G-A-P-Q-A-E-H-L-Q-A-L-R-D-G-V-A-L-N-D-G-P-T-R-P-A-Q-V-R-M-L-D-P-A-P-Q-L-W-P-R-D-P-P-V-R-V-R-K-T-V-P-D-A-W-L-E-L-Q-I-T-E-G-R-N-R-Q-V-R-R-M-T-A-A-V-G-L-P-T-L-R-L-V-R-V-A-I-G-D-W-R-L-D-A-L-A-P-G-Q-W-R-A-E-A-T-T-N-A-R-P-S-R-S-R-R"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-D-E-I-L-N-G-A-A-A-P-A-D-A-A-A-G-P-A-F-T-I-E-K-I-Y-V-K-D-V-S-F-E-S-P-N-A-P-A-V-F-N-D-A-N-Q-P-E-L-Q-L-N-L-N-Q-K-V-Q-R-L-N-D-N-A-F-E-V-V-L-A-V-T-L-T-C-T-A-G-G-K-T-A-Y-V-A-E-V-Q-Q-A-G-V-F-G-L-V-G-L-D-P-Q-A-I-D-V-L-L-G-T-Q-C-P-N-I-L-F-P-Y-V-R-T-L-V-S-D-L-I-Q-A-G-G-F-P-P-F-Y-L-Q-P-I-N-F-E-A-L-Y-A-E-T-L-R-Q-R-Q-N-E-G-T-S-L-A-D-S-E-P-A-G-N-A"} +{"text": "### FUNCTION Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in Mjannaschii 16S rRNA It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3- ### SEQUENCE -M-N-Q-T-K-S-R-D-I-P-L-Y-I-Y-H-A-G-Q-C-D-P-K-K-C-T-G-R-K-M-A-R-F-E-L-A-R-L-Y-D-R-I-S-R-L-P-R-S-A-I-L-L-D-P-M-A-E-K-A-L-S-P-A-D-D-P-K-K-G-I-I-V-L-D-C-S-W-E-E-V-E-R-V-F-P-E-L-E-K-L-N-L-E-H-R-A-L-P-Y-M-L-A-G-N-P-V-N-F-G-R-P-F-K-L-N-S-A-E-A-F-A-A-A-L-Y-I-L-G-Y-K-E-Q-A-E-K-V-M-S-K-F-N-W-G-H-S-F-L-E-L-N-R-E-P-L-E-E-Y-S-T-A-K-N-S-T-E-I-V-E-I-Q-S-H-Y-I"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-G-K-K-L-M-R-I-G-I-S-L-P-G-E-L-L-D-K-F-D-K-T-L-M-K-R-G-Y-S-S-R-S-E-G-I-R-D-A-I-R-T-Y-N-Q-H-Y-E-W-M-K-Q-I-R-G-S-R-S-A-T-I-S-I-V-Y-D-C-S-K-K-G-V-T-S-T-L-A-E-I-Q-H-E-Y-V-D-M-I-S-S-S-V-H-F-H-M-E-E-D-L-C-F-E-V-I-I-L-R-G-E-G-E-Q-I-V-D-L-A-Q-R-I-L-S-I-K-G-V-K-H-L-R-L-T-T-V-P-E-E-K-N-E"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-K-R-L-L-P-S-L-R-A-K-K-R-Y-L-A-F-E-L-I-S-E-E-P-A-S-R-S-D-I-V-K-E-V-M-S-S-A-S-S-L-L-G-D-V-T-T-S-D-C-D-I-R-V-L-G-F-E-N-G-K-G-I-I-Q-C-S-H-T-K-V-K-Q-T-R-A-S-L-A-A-L-T-R-I-N-G-K-R-A-T-L-H-V-L-G-V-S-G-T-V-K-R-A-T-E-K-F-L-Q-D-E-G-V-F-S-S"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-G-D-V-A-A-K-L-K-I-M-P-E-S-V-D-T-D-L-V-G-L-K-E-N-L-K-N-V-I-P-A-G-A-Q-L-H-G-D-I-V-E-E-P-I-A-F-G-L-K-A-L-I-V-T-L-I-V-N-D-E-E-G-G-T-E-P-A-E-E-A-F-A-K-V-S-G-V-E-N-V-Q-V-L-E-A-Y-R-I"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-R-K-R-R-E-G-T-A-N-N-S-P-T-P-E-V-T-R-V-R-T-P-R-K-E-N-H-E-V-L-A-T-V-G-S-L-L-G-S-K-R-V-N-L-Q-C-M-D-G-V-V-R-M-G-R-I-P-G-S-K-N-K-K-M-W-I-R-E-G-D-I-V-I-A-T-P-W-E-I-Q-D-S-K-A-D-V-I-W-K-Y-T-R-P-Q-I-E-W-L-E-R-K-G-Y-L-K"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-I-A-C-E-I-F-E-Q-V-K-V-T-A-E-A-H-G-A-T-E-V-K-H-V-T-L-Q-M-G-R-L-S-H-T-N-P-E-Q-L-S-F-C-F-K-T-L-A-E-G-S-I-A-E-N-A-D-L-I-V-E-M-V-P-P-T-L-E-C-E-C-G-Y-T-G-T-I-D-Q-E-R-I-R-E-S-N-E-L-T-S-E-L-L-A-Y-I-A-A-M-D-C-P-V-C-G-K-Q-A-H-I-A-G-G-R-E-L-I-I-K-S-I-E-I-E-T-E-N-E-N-E-S-Q-R"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-A-K-G-K-Y-A-A-N-I-L-K-Q-T-R-K-D-A-R-W-K-D-T-Y-Y-G-R-R-V-L-G-L-N-V-K-A-D-P-L-G-G-A-P-Q-G-R-G-I-V-L-E-K-V-G-V-E-A-K-Q-P-N-S-A-I-R-K-C-V-R-I-Q-L-I-K-N-G-R-Q-V-T-A-F-C-P-G-D-G-A-V-N-F-I-D-E-H-D-E-V-T-V-E-R-I-G-G-R-M-G-G-A-M-G-D-I-P-G-V-R-F-K-V-I-A-V-N-N-V-S-L-N-Q-L-V-I-G-R-L-E-K-P-R-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center ### SEQUENCE -M-I-F-L-Y-K-I-F-G-K-W-D-P-T-E-V-E-V-R-D-L-G-I-K-R-Y-V-S-L-A-P-V-I-V-P-H-S-S-G-K-H-A-R-Q-Q-F-N-K-S-E-I-S-I-V-E-R-L-A-N-N-L-M-R-T-E-T-N-T-G-K-K-Q-V-T-L-R-A-V-E-E-A-F-D-I-I-N-R-K-T-Q-Q-N-P-I-Q-I-L-V-D-A-I-A-N-A-G-P-R-E-E-V-V-R-L-K-Y-G-G-I-S-V-P-K-A-V-D-T-A-P-Q-R-R-V-D-T-A-L-R-Y-I-S-M-G-T-N-A-A-A-F-K-S-K-R-S-V-A-E-C-L-A-T-E-L-I-G-A-A-N-R-D-T-K-S-F-S-I-N-R-K-D-A-K-E-R-V-A-K-A-A-R"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-E-S-T-I-T-I-E-N-V-V-A-S-T-R-L-A-E-D-F-D-L-E-K-M-M-E-S-G-L-E-G-A-E-Y-N-K-V-K-F-P-G-L-V-Y-R-I-N-N-P-K-A-A-F-L-I-F-T-S-G-K-V-V-C-T-G-S-K-S-I-G-N-A-H-A-A-I-I-N-L-A-N-T-L-K-S-I-C-C-E-K-I-D-L-E-P-D-V-R-V-Q-N-I-V-A-S-A-D-L-K-T-N-L-N-L-N-T-I-A-I-A-F-G-L-E-N-V-E-Y-E-P-E-V-F-P-G-L-I-Y-R-V-E-A-P-K-V-V-V-L-V-F-S-S-G-K-L-V-I-T-G-G-K-C-P-E-D-C-E-E-G-L-R-I-V-K-T-E-F-D-N-L-G-L-L-Y"} +{"text": "### FUNCTION Located on the platform of the 30S subunit ### SEQUENCE -M-A-D-M-K-W-A-V-A-H-I-K-S-S-F-N-N-T-I-I-T-V-T-D-I-T-G-A-E-T-I-A-K-S-S-G-G-M-V-V-K-A-A-R-D-E-S-S-P-Y-T-A-M-Q-M-A-G-Q-L-A-D-Q-L-R-D-K-G-I-N-G-I-H-I-R-V-R-A-P-G-G-N-K-Q-R-S-P-G-P-G-A-Q-A-A-I-R-A-F-A-R-A-G-I-R-I-G-R-I-E-D-V-T-P-V-P-H-D-G-T-R-P-K-G-G-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-L-H-A-L-Q-W-R-K-Y-M-A-E-E-N-N-N-E-E-L-R-H-L-V-R-I-M-N-T-D-L-K-G-A-K-P-V-E-Y-A-L-T-G-L-P-G-I-G-R-R-T-A-I-L-I-A-K-G-A-G-V-D-P-T-A-T-L-G-Y-L-P-D-E-E-V-A-K-L-D-A-A-I-G-K-F-E-E-I-V-P-S-W-M-L-N-R-Q-K-D-L-T-T-G-Q-D-K-H-L-L-G-T-D-I-L-L-T-F-R-E-D-I-N-N-L-K-K-V-R-A-Y-R-G-L-R-H-E-R-G-L-K-V-R-G-Q-R-T-K-S-T-G-R-R-G-S-T-V-G-V-S-R-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-D-I-K-K-F-R-G-S-R-T-C-G-G-G-T-H-K-N-R-R-G-A-G-N-R-G-G-R-G-K-A-G-G-C-K-H-H-F-V-R-A-M-M-R-G-Y-S-Y-G-K-H-G-F-K-R-P-V-E-V-S-K-D-I-S-I-V-N-V-G-E-L-D-E-L-A-P-Y-L-V-E-E-G-L-A-E-V-K-D-G-A-Y-H-I-N-L-E-N-L-G-I-E-K-V-L-G-S-G-R-V-T-K-N-L-V-V-T-S-E-E-F-S-A-S-A-R-E-K-I-E-N-A-G-G-S-C-I-D-A-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-T-G-P-R-Y-K-V-P-F-R-R-R-R-E-G-R-T-N-Y-H-L-R-L-K-L-L-L-S-G-Q-D-R-V-V-V-R-K-S-A-R-N-V-Q-I-Q-L-L-A-P-T-P-E-G-D-I-T-Y-S-S-A-V-S-S-E-L-A-K-Y-G-Y-T-G-A-T-G-N-T-T-A-A-Y-L-T-G-L-L-F-G-L-K-S-L-Q-K-G-Y-E-G-G-I-L-D-I-G-L-Q-A-S-S-A-G-S-R-V-Y-A-A-L-K-G-I-V-D-S-G-F-E-I-P-C-S-S-D-V-F-P-S-D-E-R-I-R-G-E-H-I-A-E-Y-R-E-E-S-S-D-L-P-E-Q-F-E-A-T-K-E-K-I-F-A-E-F-S"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-V-K-E-I-A-R-T-I-E-I-P-E-G-V-S-V-S-L-S-Q-D-V-F-T-A-K-G-P-K-G-T-V-E-R-T-F-W-Y-P-G-I-K-I-E-V-R-E-G-E-V-V-V-D-A-E-S-S-R-K-E-Q-K-A-M-V-G-T-F-A-S-H-L-K-N-L-I-I-G-V-S-E-G-F-E-C-K-M-N-I-V-Y-A-H-F-P-M-Q-V-K-V-E-G-K-T-L-V-I-G-N-F-L-G-E-K-K-P-R-I-A-K-I-L-G-E-T-K-V-K-V-S-G-N-E-I-V-V-S-G-I-N-K-E-D-V-G-Q-T-A-A-N-I-E-Q-K-T-K-I-K-R-F-D-P-R-I-F-Q-D-G-I-Y-I-V-Q-K-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-L-L-D-P-L-A-N-A-L-S-T-I-K-N-A-E-A-I-G-K-S-S-C-I-V-R-P-A-S-K-N-I-G-N-V-L-K-V-M-Q-D-L-G-Y-I-G-D-F-E-F-I-D-D-G-K-A-G-I-Y-S-V-T-L-V-G-R-I-N-K-C-G-A-I-K-P-R-Y-S-V-G-T-G-S-F-E-R-W-E-K-Q-F-L-P-A-K-N-F-G-A-L-I-L-T-T-S-S-G-V-M-S-Q-Y-E-A-R-D-K-K-I-G-G-Q-L-L-A-Y-V-Y"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-T-D-S-I-D-K-S-G-R-G-V-N-E-C-K-R-C-G-R-K-Q-G-L-V-R-K-Y-D-I-Y-L-C-R-H-C-F-R-E-I-A-H-E-M-G-F-E-K-Y-S"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-N-P-M-R-T-P-M-V-E-K-V-I-V-H-M-G-V-G-E-S-G-Q-H-L-V-N-A-E-E-I-L-K-T-I-T-G-Q-E-V-V-R-C-F-A-K-R-T-L-P-A-F-S-I-K-K-N-E-P-I-G-C-K-V-T-L-R-G-Q-R-A-Q-E-F-L-G-T-S-F-E-I-I-E-K-T-L-S-R-A-Q-F-D-S-L-G-N-V-S-F-G-I-E-E-H-T-D-F-P-G-M-R-Y-D-P-N-I-G-V-F-G-M-D-V-T-V-V-L-K-R-P-G-E-R-I-C-K-R-R-I-A-T-R-K-I-P-T-D-H-R-V-T-V-D-D-A-I-A-F-L-N-E-S-Y-G-V-E-V-M"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-E-V-I-E-M-V-S-K-Q-P-R-K-Q-R-K-A-R-Y-T-A-P-L-H-I-R-Q-K-F-M-G-A-R-L-S-E-A-L-A-K-Q-Y-G-T-R-S-A-A-V-I-T-G-D-T-V-K-I-M-R-G-D-F-K-G-T-E-G-K-V-Q-S-V-S-L-M-D-G-T-I-A-V-D-G-V-I-S-T-K-V-D-G-T-E-V-P-R-P-I-N-P-S-N-V-M-I-T-K-L-E-M-K-D-G-R-R-A-S-S-I-K-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-K-G-I-R-S-N-I-P-R-A-L-N-A-G-A-Q-I-A-C-V-D-N-T-G-A-K-V-V-E-I-I-S-V-K-K-Y-R-G-V-K-N-R-M-P-C-A-G-I-G-D-M-C-V-V-S-V-K-K-G-T-P-E-M-R-K-Q-I-L-L-A-V-V-V-R-Q-K-Q-E-F-R-R-P-D-G-L-H-V-S-F-E-D-N-A-M-V-I-T-D-E-D-G-I-P-K-G-T-D-I-K-G-P-V-A-R-E-V-A-E-R-F-P-K-I-G-T-T-A-S-I-I-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-R-D-I-G-L-N-I-P-A-P-S-E-E-C-D-D-A-Y-C-P-F-H-G-T-L-P-V-R-G-Q-I-L-V-G-T-V-V-S-S-K-M-D-N-T-V-V-I-E-R-Q-Y-M-K-M-V-S-K-Y-Q-R-Y-E-K-R-R-S-K-I-H-A-H-N-P-A-C-I-S-A-K-V-G-D-I-V-T-I-V-E-C-R-P-I-S-K-T-K-S-F-V-V-V-K-A-E-V-P-K"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-R-S-K-V-E-I-L-P-S-T-L-I-F-H-E-L-I-G-L-E-I-K-V-S-N-S-T-N-P-S-L-I-G-I-R-G-R-V-I-N-E-T-K-N-M-L-V-V-E-N-S-E-S-R-E-L-K-I-P-K-A-D-S-E-F-V-F-R-I-P-A-E-L-S-E-K-G-R-R-S-D-I-F-V-K-I-Q-G-N-L-L-L-S-Q-P-E-N-R-I-K-N-I-K-K-L-R-K-W-G"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-A-R-I-N-Y-S-I-N-A-D-P-E-N-T-S-K-A-M-G-S-E-L-H-I-S-P-K-K-S-R-E-V-C-C-K-I-K-G-M-K-A-S-E-A-R-K-F-L-E-D-V-I-A-M-K-Q-A-V-P-F-K-R-H-S-E-G-A-G-H-R-K-G-P-M-A-G-G-R-Y-P-V-S-A-S-K-E-I-L-K-V-L-K-N-A-E-S-N-A-E-Y-K-G-L-E-P-A-N-M-Y-I-I-H-A-A-I-Q-R-G-R-V-I-H-G-F-M-P-R-A-R-G-R-A-S-P-K-D-T-E-T-V-N-I-E-M-I-L-S-E-V-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-K-K-S-S-S-R-L-P-K-R-K-G-E-Y-T-Y-R-G-K-T-V-S-E-L-Q-E-L-S-L-E-E-F-A-E-L-L-P-S-R-E-R-R-S-I-K-R-G-F-T-D-G-Q-K-K-V-L-H-E-F-K-E-G-K-K-I-R-T-H-H-R-D-M-I-I-L-P-E-M-I-G-I-A-I-E-V-H-N-G-K-E-F-V-N-V-E-L-Q-P-E-M-I-G-H-R-F-G-E-F-A-P-T-R-S-R-V-N-H-G-S-A-G-V-G-A-T-R-S-S-K-F-V-P-L-K"} +{"text": "### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-S-S-I-N-Y-P-F-V-T-E-K-A-M-M-L-L-D-E-N-K-L-Q-F-I-V-D-T-R-S-N-K-K-Q-I-V-E-D-V-E-K-L-Y-G-F-K-V-K-A-V-R-T-M-T-T-M-K-G-T-K-K-A-V-L-A-F-E-E-P-E-A-A-H-E-I-A-T-R-I-G-L-M"} +{"text": "### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-F-P-G-M-G-G-V-G-G-R-G-M-N-P-A-K-M-K-Q-M-M-K-Q-M-G-I-D-V-K-E-L-K-D-V-E-E-V-V-I-K-T-A-D-S-N-I-V-I-E-N-A-N-V-T-I-M-T-V-Q-G-S-E-T-Y-Q-I-V-G-D-V-K-E-V-P-K-S-L-E-I-P-A-E-D-I-K-L-V-M-E-Q-T-G-V-S-E-E-E-A-R-N-A-L-K-N-S-N-G-D-L-A-E-A-I-V-A-L-S-S-A"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-T-L-A-D-L-K-K-P-T-S-R-A-S-P-S-T-E-E-T-V-T-R-V-R-T-P-R-R-E-N-N-E-I-L-A-T-V-E-S-L-L-G-A-N-R-L-R-L-R-C-M-D-G-V-V-R-M-G-R-I-P-G-S-M-K-K-K-A-W-I-R-E-G-D-V-V-I-A-V-P-W-E-F-Q-N-E-K-A-D-V-I-W-K-Y-T-R-P-Q-V-D-W-L-E-R-K-G-Y-L-K-G"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-I-V-K-P-I-G-E-R-V-L-L-K-H-Q-K-K-E-E-V-T-K-G-G-I-Y-I-P-E-S-A-R-Q-E-K-K-E-G-I-V-V-A-V-G-T-F-E-D-G-K-E-L-P-L-K-K-D-D-H-V-I-Y-G-G-Y-Q-A-D-E-I-E-I-D-D-E-K-Y-I-F-V-D-F-K-D-I-L-A-T-V-V-E-E"} +{"text": "### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates ### SEQUENCE -M-S-N-L-S-C-F-S-I-I-G-T-H-R-S-V-F-K-F-K-G-D-L-L-V-K-E-N-Y-T-R-F-E-R-A-R-I-V-G-A-R-A-L-Q-I-A-M-G-A-P-V-L-V-E-D-D-G-R-L-D-P-L-G-V-A-I-E-E-L-K-A-G-V-I-P-I-T-V-K-R-K-K-S"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-T-V-I-D-A-K-G-L-I-L-G-R-L-A-S-S-V-A-K-Q-L-L-S-G-D-E-K-V-Y-I-I-N-A-E-K-A-I-I-S-G-S-R-A-A-T-L-R-E-Y-R-E-T-R-D-R-G-A-T-E-F-G-P-Y-F-P-K-R-P-D-R-I-L-K-R-T-I-R-G-M-L-P-Y-K-R-A-R-G-R-D-A-M-S-R-L-K-V-Y-V-G-V-P-Y-E-L-K-G-A-E-T-T-T-I-A-D-A-D-M-R-L-L-S-S-N-K-Y-V-E-L-G-E-V-S-Q-K-M-G-S-K-F"} +{"text": "### FUNCTION Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base ### SEQUENCE -M-Y-S-K-E-S-C-E-R-C-E-E-M-E-K-I-I-P-S-G-Q-G-K-K-S-I-F-L-S-G-S-I-R-G-G-R-Q-L-L-E-T-Y-R-F-I-Y-D-A-L-E-E-A-G-A-E-V-L-S-W-H-V-A-D-P-E-L-E-K-T-E-S-K-M-T-E-Q-E-I-Y-A-R-D-L-G-L-L-E-K-S-D-A-L-I-A-E-V-T-V-P-S-T-G-V-G-Y-E-I-C-R-A-L-V-R-K-I-P-V-L-C-L-H-M-P-D-V-A-V-S-S-M-V-L-G-N-P-D-T-L-M-E-V-R-S-Y-P-D-K-E-A-L-K-E-I-I-I-D-F-I-R-A-L"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-A-L-L-S-S-N-E-L-R-K-L-I-K-A-N-P-P-L-L-E-N-A-V-D-T-E-T-Q-I-Q-P-N-G-L-E-L-T-L-K-E-I-K-T-I-E-G-A-G-A-V-D-F-D-N-S-E-R-K-V-P-D-A-K-P-L-E-F-G-K-D-G-W-I-H-L-P-E-G-I-Y-K-V-I-F-N-E-I-V-N-I-P-M-N-L-A-A-I-A-K-P-R-S-S-L-I-R-C-G-A-T-L-E-T-A-V-W-D-A-G-Y-R-G-R-S-E-S-M-L-V-V-Y-N-P-A-G-F-K-L-K-K-N-A-R-I-M-Q-L-L-F-Y-T-L-N-T-E-V-E-E-G-Y-S-G-V-Y-Q-N-E-N-T-N"} +{"text": "### FUNCTION Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP ### SEQUENCE -M-K-D-K-G-K-L-V-I-W-P-A-Y-I-D-Q-T-K-S-R-S-S-G-R-I-I-S-R-K-N-S-I-K-E-P-H-L-N-E-I-K-E-A-A-R-Q-L-G-L-N-P-E-V-E-P-E-K-A-Y-P-K-S-W-W-E-V-S-G-R-V-L-V-D-D-N-G-P-K-S-V-I-A-K-Q-I-A-L-A-I-K-K-M-R-G-Q-E-V-P-A-K-T"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently ### SEQUENCE -M-P-S-Q-G-K-K-Y-E-Y-L-E-H-T-A-D-I-K-F-L-A-Y-G-E-T-V-E-E-V-F-E-N-A-A-L-A-M-F-N-V-I-I-D-T-E-K-V-S-G-E-T-E-R-E-V-L-L-T-S-P-D-L-E-S-L-L-V-D-W-L-S-E-L-L-Y-L-F-E-V-D-E-V-V-F-W-K-F-Q-V-E-E-I-R-E-E-E-G-E-Y-S-I-K-A-L-A-S-G-E-K-Y-Y-P-E-S-H-P-F-E-T-E-I-K-A-V-T-Y-N-Q-L-E-L-E-K-T-A-G-G-W-K-A-Q-V-V-V-D-I"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-K-G-R-A-W-K-F-G-D-D-V-D-T-D-A-V-I-P-G-R-Y-L-I-F-N-T-P-G-E-L-A-K-Y-T-F-E-G-V-R-P-D-F-A-K-N-V-H-E-N-D-I-V-V-A-G-S-N-F-G-C-G-S-S-R-E-H-A-P-L-A-L-K-G-S-K-V-S-C-V-I-A-K-S-F-A-R-I-F-F-R-N-A-I-N-I-G-V-P-V-L-E-C-P-D-T-D-K-I-D-D-G-D-E-L-E-V-D-I-S-T-G-V-I-Q-N-R-T-K-G-E-T-Y-Q-A-T-P-L-P-D-F-V-R-E-I-V-D-E-G-G-L-I-E-Y-A-R-K-L-V-S-E-R"} +{"text": "### FUNCTION Involved in protein export The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex ### SEQUENCE -M-A-K-K-S-G-S-G-L-Q-S-S-A-G-L-M-R-Y-Y-E-A-D-K-N-A-I-H-I-Q-P-K-T-V-L-I-A-G-A-L-V-G-I-A-V-I-F-L-S-A-V-N-G-F-W-P"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-V-N-S-D-I-I-T-V-G-I-G-D-C-A-I-A-R-S-P-M-K-I-K-T-S-G-L-G-S-C-L-G-I-T-L-Y-D-R-Q-K-K-I-G-G-L-L-H-T-M-L-P-N-I-K-D-A-K-L-K-D-N-P-A-K-F-T-D-A-G-I-E-Y-L-V-D-E-M-I-R-R-G-G-S-I-D-K-L-E-A-K-V-V-G-G-A-G-M-F-E-N-S-R-L-N-I-G-E-R-N-I-K-S-A-R-E-T-M-K-K-L-G-V-S-I-I-A-E-D-V-G-K-N-Y-G-R-T-V-I-F-D-T-L-T-G-D-L-L-I-K-T-I-L-K-G-D-K-L-I"} +{"text": "### FUNCTION Catalyzes the synthesis of GMP from XMP ### SEQUENCE -M-R-E-L-K-I-L-V-V-N-N-Y-G-Q-F-C-H-L-I-H-R-T-V-R-D-L-D-M-D-T-K-I-I-P-N-V-T-P-I-E-E-I-L-A-E-E-P-D-G-L-I-L-S-G-G-P-E-M-E-R-A-G-L-C-F-D-Y-V-R-E-I-D-V-P-I-L-G-I-C-L-G-H-Q-A-I-A-L-A-Y-G-G-H-V-H-A-G-K-K-G-G-Y-A-E-I-E-V-E-V-L-E-E-D-D-I-L-R-G-L-G-P-K-T-T-V-W-A-S-H-A-D-E-V-A-I-L-P-D-G-F-I-H-L-A-R-S-D-V-C-E-I-E-A-M-R-H-P-T-K-P-I-Y-G-V-Q-W-H-P-E-V-S-H-T-K-K-G-E-E-L-L-M-N-F-F-E-V-C-D-L-Y"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-K-E-K-R-D-L-K-V-Q-A-I-E-S-G-T-V-I-D-H-I-K-S-G-Q-A-L-N-V-L-R-I-L-G-I-S-S-A-F-R-A-T-I-S-F-V-M-N-A-P-G-A-G-G-K-K-D-V-V-K-I-E-G-K-E-L-S-V-E-E-L-N-R-I-A-L-I-S-P-K-A-T-I-N-I-I-R-D-F-V-V-V-Q-K-N-N-V-V-L-P-S-Y-V-E-G-V-V-R-C-T-N-S-S-C-I-S-N-S-S-E-P-I-K-S-K-F-S-V-I-Q-S-E-E-E-G-V-S-L-H-C-L-Y-C-E-H-V-I-S-E-E-I-A-E-N-L-L"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-S-E-S-S-I-K-I-E-N-V-V-A-S-T-K-L-A-E-E-F-D-L-T-V-I-E-S-Q-F-E-G-A-E-Y-N-K-Q-K-F-P-G-L-V-Y-R-V-S-D-P-K-A-A-F-L-V-F-T-S-G-K-V-V-C-T-G-A-K-N-V-A-D-V-H-T-V-I-G-N-M-A-K-K-L-N-S-I-G-I-K-T-M-E-N-P-Q-I-T-V-Q-N-I-V-A-S-A-D-L-H-T-I-L-N-L-N-A-I-A-I-G-L-G-L-E-N-I-E-Y-E-P-E-Q-F-P-G-L-V-Y-R-I-D-E-P-K-V-V-V-L-I-F-S-S-G-K-L-V-V-T-G-G-K-T-P-E-D-C-E-S-G-V-E-V-V-R-Q-Q-L-D-N-M-G-L-L"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-S-E-S-S-I-K-I-E-N-V-V-A-S-T-K-L-A-E-E-F-D-L-T-V-I-E-S-E-F-E-G-A-E-Y-N-K-Q-K-F-P-G-L-V-Y-R-V-S-D-P-K-A-A-F-L-V-F-T-S-G-K-V-V-C-T-G-T-K-N-V-A-D-V-H-T-V-V-G-N-L-A-K-K-L-N-S-I-G-I-K-T-I-E-N-P-Q-I-T-V-Q-N-I-V-A-S-A-D-L-H-T-I-L-N-L-N-A-I-A-I-G-L-G-L-E-N-I-E-Y-E-P-E-Q-F-P-G-L-V-Y-R-I-D-E-P-K-V-V-V-L-I-F-S-S-G-K-L-V-V-A-G-G-K-S-P-E-D-C-E-R-S-V-E-V-V-R-Q-Q-L-D-S-M-G-L-L"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-T-S-I-V-E-A-L-V-P-G-G-K-A-N-P-G-P-P-L-G-P-A-L-G-P-L-G-V-N-I-K-E-V-V-E-K-I-N-E-K-T-R-D-Y-N-G-M-Q-V-P-V-K-V-I-V-D-D-K-K-N-V-E-I-E-V-G-T-P-P-T-A-S-L-V-M-K-E-L-G-I-Q-K-G-S-G-N-A-G-S-E-V-V-G-N-L-T-I-P-Q-V-A-K-I-A-R-M-K-K-E-D-V-L-S-Y-D-L-K-A-T-M-K-E-V-M-G-T-C-V-P-M-G-V-N-V-E-G-M-K-A-K-D-C-Q-K-A-L-D-E-G-K-F-D-D-L-L-A-N-E-A-W"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-V-E-S-A-L-E-P-N-I-T-T-K-S-V-G-Q-A-I-R-A-H-L-R-V-L-K-L-T-K-K-P-S-R-E-E-F-L-T-I-A-K-V-A-G-A-G-I-L-A-V-G-A-V-G-F-I-I-Y-V-L-L-T-M-L-P-Q-W-V-A-K"} +{"text": "### FUNCTION Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7 ### SEQUENCE -M-S-E-I-V-S-V-S-G-G-P-T-K-P-E-I-I-A-V-S-L-S-K-L-G-L-K-D-G-D-R-F-A-D-V-G-C-G-T-G-S-V-S-I-E-A-A-R-I-A-R-N-L-T-I-Y-A-I-D-A-R-K-E-A-L-L-A-T-E-T-N-F-K-N-F-G-I-E-N-A-R-I-L-A-G-E-A-S-D-I-L-G-S-E-K-T-I-D-S-I-D-C-A-F-V-G-G-T-K-N-I-G-S-I-L-A-K-L-V-E-K-K-A-R-S-I-V-V-N-A-V-R-I-E-T-V-V-R-T-I-E-A-M-K-S-L-D-I-F-D-E-V-I-H-V-A-V-S-R-S-F-P-I-A-G-E-T-M-F-K-P-E-N-P-V-Y-I-V-V-G-K-K-Q-S"} +{"text": "### FUNCTION Functions by promoting the formation of the first peptide bond ### SEQUENCE -M-K-Q-Q-V-E-V-K-E-L-K-E-G-K-Y-V-I-I-D-D-E-A-C-V-I-K-S-I-T-K-S-K-P-G-K-H-G-A-A-K-A-R-V-E-A-I-G-L-F-D-G-Q-K-R-S-Y-I-G-S-V-A-N-K-V-Y-V-P-I-V-E-R-K-S-A-Q-V-I-S-I-T-G-D-I-A-Q-L-M-D-M-G-D-F-S-T-F-E-I-V-I-P-D-E-L-K-D-R-V-K-E-G-E-E-V-S-Y-I-T-A-L-G-K-V-K-L-D-I-R-T"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-E-T-E-L-M-R-I-G-V-S-L-P-D-T-L-L-S-K-F-D-E-I-I-E-K-R-G-Y-S-S-R-S-E-G-I-R-D-A-I-R-S-Y-I-S-Y-Y-E-W-M-G-D-I-K-G-H-R-V-G-T-V-A-V-I-Y-D-H-T-K-R-G-L-S-N-A-L-A-D-I-Q-H-H-Y-S-H-L-I-K-S-S-V-H-I-H-L-D-H-D-N-C-F-E-V-V-V-L-D-G-D-G-E-E-I-K-E-L-A-E-A-I-M-S-L-K-G-V-K-F-S-K-L-T-T-V-A-S-N-E-K-I"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-P-S-P-D-K-E-M-D-K-V-L-L-I-G-L-G-G-F-L-G-A-V-C-R-F-L-I-C-E-H-V-D-G-Q-L-G-I-L-S-V-N-V-L-G-S-F-M-L-G-M-I-M-Y-D-A-E-Y-L-S-F-I-G-P-K-G-R-L-A-F-G-T-G-F-I-G-A-F-T-T-F-S-T-F-A-V-Q-S-F-S-M-A-F-L-P-A-L-G-N-I-S-A-N-L-F-L-T-L-T-G-V-F-F-G-R-S-F-I-K-A-L-S-S-R-E-I"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-P-A-A-N-I-G-D-L-F-L-I-G-T-G-G-F-I-G-A-S-L-R-Y-T-I-S-S-R-M-P-K-I-R-S-I-P-A-G-T-L-T-V-N-F-L-G-S-I-V-L-S-L-L-T-F-S-S-E-P-E-S-V-V-Y-L-V-N-I-G-I-L-G-S-F-T-T-F-S-T-F-A-Y-E-T-F-K-L-L-E-D-G-Q-N-V-S-F-F-L-N-I-F-L-N-V-I-L-C-L-L-G-V-G-I-A-Y-F-A-L-R-L"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-A-E-V-S-E-E-I-R-N-L-A-A-R-H-Q-E-F-Q-R-Q-A-E-A-L-R-Q-E-M-S-M-V-Q-A-S-I-A-S-C-D-Q-A-I-A-T-I-N-E-L-K-A-A-S-E-A-G-R-A-A-E-T-M-V-P-V-G-F-G-S-Y-V-Y-A-E-V-K-N-P-D-K-V-V-V-N-L-G-A-G-F-S-A-E-E-T-A-E-A-A-V-E-T-L-N-R-R-K-E-Q-L-T-K-I-L-E-Q-M-N-A-S-L-T-K-I-A-Q-G-M-Q-A-L-E-T-E-A-A-K-I-Q-P-G-Q-A"} +{"text": "### FUNCTION Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein and RNA polymerase recruitment Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes ### SEQUENCE -M-V-D-L-N-D-K-V-I-R-G-Y-L-R-S-L-V-G-D-D-G-L-K-M-I-E-Q-M-P-E-G-N-V-T-D-E-E-I-A-A-K-T-G-V-L-L-N-T-V-R-R-T-L-F-I-L-Y-E-N-K-F-A-I-V-V-R-E-R-D-S-N-S-G-W-L-T-Y-L-W-H-L-D-F-S-D-I-E-H-Q-L-M-R-E-K-K-R-L-L-R-N-L-K-T-R-L-E-F-E-E-N-H-V-F-Y-V-C-P-Q-G-C-V-R-L-L-F-D-E-A-T-E-T-E-F-L-C-P-M-C-G-E-D-L-V-Y-Y-D-N-S-R-F-V-G-V-L-K-K-R-V-E-A-L-S-S-A"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-T-S-E-L-P-P-Q-I-Q-N-Q-I-A-Q-L-Q-Q-V-Q-Q-Q-V-Q-A-L-S-M-Q-K-S-Q-I-E-A-M-Q-K-E-S-K-M-A-L-E-E-L-E-R-L-A-D-D-A-V-I-Y-R-S-V-G-E-L-V-I-K-T-T-K-E-E-S-V-S-K-L-K-D-R-E-E-T-L-S-L-R-L-Q-S-I-S-R-Q-E-E-R-L-T-A-R-F-K-Q-L-Q-E-Q-I-Q-Q-A-L-G-P-R-A-Q"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-E-T-E-L-M-R-I-G-V-S-L-P-D-T-L-L-G-K-F-D-E-I-I-E-K-R-G-Y-S-S-R-S-E-A-I-R-D-S-I-R-S-Y-I-S-Y-N-E-W-M-G-N-I-K-G-H-H-V-G-T-I-V-I-I-Y-D-H-T-Q-R-G-L-S-N-V-L-T-D-I-Q-H-H-Y-S-H-L-I-R-S-S-I-H-I-Y-P-D-R-E-D-C-F-E-I-V-V-L-E-G-E-G-K-E-I-T-E-L-A-E-A-I-M-A-L-K-G-V-K-L-S-K-L-I-T-T-E-S-N-E-T-D-E-P-S-I-V-I"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-S-F-L-T-N-F-L-L-G-L-G-L-A-M-D-A-F-A-V-S-M-S-S-G-T-T-V-R-P-F-K-V-S-D-A-L-K-L-A-V-F-F-G-G-F-Q-A-L-M-P-V-L-G-W-V-G-G-S-A-V-S-G-F-V-S-D-Y-A-P-W-I-A-F-G-L-L-A-F-I-G-G-K-M-I-Y-E-A-L-Y-G-D-P-D-G-K-V-N-S-L-N-Y-S-M-L-F-L-L-A-V-A-T-S-I-D-A-L-A-V-G-I-S-F-A-F-L-G-T-P-I-L-E-P-V-I-I-I-G-C-V-T-F-V-M-S-F-C-G-A-V-L-G-Y-R-I-G-H-F-F-E-N-E-V-E-I-L-G-G-L-I-L-I-G-L-G-V-K-I-L-A-E-H-M-D-W-I"} +{"text": "### FUNCTION Broad-specificity nucleoside monophosphate kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-L-I-G-L-T-G-T-P-G-T-G-K-T-S-V-S-K-L-L-E-K-R-R-G-W-K-V-V-Y-L-N-D-L-I-K-E-E-H-L-Y-S-E-V-D-E-E-R-D-S-V-I-A-D-M-E-L-I-R-E-R-L-S-G-I-L-E-E-E-K-G-Q-H-A-E-K-A-K-V-N-G-E-E-K-E-N-I-T-I-I-E-S-H-L-A-H-Y-I-T-D-I-V-I-V-L-R-A-Y-P-P-E-L-K-K-R-L-E-K-R-G-Y-S-E-E-K-I-N-E-N-A-E-A-E-S-I-D-L-I-L-A-E-A-F-E-W-C-K-K-V-F-E-V-N-T-T-G-R-T-A-E-E-T-L-G-D-V-E-K-I-I-D-Y-I-L-A-G-K-E-N-E-L-Q-E-Y-I-P-G-S-L-D-W-I-D-S-V-P"} +{"text": "### FUNCTION Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A ### SEQUENCE -M-S-V-H-I-E-L-P-R-E-L-R-P-L-M-K-K-P-L-G-I-L-Y-R-G-K-G-R-D-T-I-E-K-F-A-G-E-L-S-S-P-T-K-L-I-S-V-G-D-V-T-T-F-H-L-L-E-A-G-I-I-P-D-I-C-I-V-D-D-R-T-K-R-K-P-V-S-S-D-V-S-V-R-N-R-D-K-V-Y-E-E-V-S-V-D-N-P-A-G-I-I-T-D-E-L-I-R-T-L-C-E-A-F-A-S-E-K-L-L-R-I-F-V-R-G-E-E-D-L-A-T-L-P-V-I-L-L-A-P-P-G-S-V-V-L-Y-G-Q-P-D-E-G-V-V-F-V-E-V-T-E-K-K-K-E-E-I-R-A-L-F-E-K-L-I-S-K-N-Q-N-N-E-L-D-K-I-R-R-I-L-D-G-H-K-D-N"} +{"text": "### FUNCTION Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA and pyrophosphate ### SEQUENCE -M-P-K-V-A-V-G-G-T-F-Q-Y-L-H-D-G-H-A-R-L-I-E-K-A-F-E-I-A-G-S-G-K-V-Y-I-G-L-T-S-D-E-M-L-Q-K-N-H-S-V-E-S-Y-K-I-R-R-S-R-L-L-E-Y-I-K-K-M-G-V-P-E-E-K-Y-E-V-T-R-L-N-D-P-C-G-P-T-I-E-E-D-F-D-H-I-I-V-S-P-E-T-Y-P-V-A-L-K-I-N-T-I-R-E-K-K-G-K-K-P-L-E-I-V-Y-V-E-Y-V-M-A-E-D-G-I-P-I-S-S-T-R-I-S-K-G-E-I-D-R-H-G-R-L-K-K-E-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-S-K-G-T-A-S-M-G-K-R-Q-K-R-T-H-A-K-C-R-R-C-G-S-V-S-L-N-V-H-T-K-Q-C-T-S-C-G-F-G-K-T-S-R-M-R-T-Y-K-W-Q-A-K-C-K-Y"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-I-S-L-G-F-V-V-A-E-F-N-R-D-L-T-Y-Q-M-E-L-L-G-R-E-H-A-E-F-L-G-A-T-V-K-E-T-I-L-V-P-G-V-F-D-M-P-L-A-I-K-K-L-C-Q-R-E-D-I-D-A-V-V-T-I-G-S-V-I-E-G-E-T-D-H-D-Q-V-V-M-Q-H-A-A-R-K-I-M-D-L-S-L-E-F-N-K-P-V-T-L-G-I-P-G-P-G-M-T-R-M-A-A-H-E-R-V-D-Y-A-K-R-A-V-E-A-A-V-K-L-V-R-R-L"} +{"text": "### FUNCTION May play a role in purine salvage ### SEQUENCE -M-R-Q-E-S-L-V-T-K-Y-D-Y-D-F-E-N-D-S-I-F-F-Y-G-S-N-K-K-Y-R-S-S-I-D-L-D-G-I-I-L-D-I-G-E-D-D-Q-I-M-A-I-E-I-L-D-A-S-N-R-F-N-L-A-K-E-D-L-R-N-I-K-Y-F-E-A-R-I-E-V-S-E-E-N-I-R-L-T-M-K-M-S-V-N-K-R-N-K-L-V-D-K-G-L-D-A-L-G-L-N-S-I-N-L-P-I-S-T-Q-G-I-E-L-N-C"} +{"text": "### FUNCTION Converts adenosylcobinamide , an intermediate of the de novo coenzyme B12 biosynthetic route ### SEQUENCE -M-Q-Y-H-I-K-D-Q-T-L-I-I-K-G-D-F-E-A-V-S-T-G-L-N-G-G-R-A-R-V-E-Y-I-F-N-K-Q-V-P-R-T-F-N-P-P-S-P-E-E-F-I-R-E-E-A-R-K-D-G-I-E-T-A-S-L-G-L-L-T-A-V-N-M-E-Y-L-Q-V-I-E-D-D-Y-M-T-A-F-I-T-A-G-V-S-N-C-S-E-F-R-A-K-A-G-T-I-N-I-I-L-V-S-K-A-R-L-S-E-T-A-L-F-G-A-I-I-T-A-T-E-A-K-G-L-A-L-L-E-K-G-Y-N-F-L-G-T-N-T-D-A-V-I-V-A-Y-E-T-C-S-D-S-G-P-K-S-K-T-N-Q-E-I-P-Y-A-G-S-S-T-E-F-G-K-K-I-T-E-A-V-I-K-G-I-K-A-G-L-E-L-R-G-E"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-S-K-T-N-S-E-T-G-N-N-F-E-Q-Q-K-Q-E-L-I-A-A-L-K-A-C-G-A-V-R-Y-G-D-F-T-L-A-S-G-K-K-S-K-Y-Y-I-D-I-K-K-A-S-T-D-P-K-T-L-K-I-I-A-R-Q-A-A-L-R-I-K-E-M-D-V-D-T-V-A-G-V-E-L-G-G-V-P-L-A-T-A-V-S-L-E-T-E-L-P-L-L-I-V-R-K-S-V-K-D-Y-G-T-K-S-R-F-V-G-D-L-K-P-E-D-R-L-V-M-L-E-D-V-T-T-S-G-G-S-V-R-D-A-I-E-V-V-R-E-A-G-A-S-L-K-Y-V-I-T-V-V-D-R-E-E-G-A-G-E-K-L-K-E-A-D-V-E-L-V-P-L-V-S-A-S-D-L-L-K"} +{"text": "### FUNCTION Catalyzes the formation of CDP-2,3-bis- and CTP This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-I-P-A-Y-L-S-N-P-F-A-A-V-F-G-G-G-K-P-I-D-G-G-R-T-Y-K-D-G-R-R-I-L-G-D-G-K-T-Y-R-G-L-F-S-G-I-F-C-G-F-L-A-G-C-V-E-V-W-L-S-F-R-G-F-E-I-L-G-I-E-M-P-G-F-G-P-D-Y-T-S-S-L-I-V-V-L-A-L-A-S-G-A-L-F-G-D-M-F-K-S-F-F-K-R-R-M-G-L-K-R-G-A-S-L-P-L-V-D-Q-L-D-F-V-V-G-A-W-V-F-T-Y-L-A-A-P-E-W-F-V-S-N-F-T-P-G-I-M-L-T-V-I-I-I-T-P-L-L-H-L-T-T-N-I-I-G-Y-F-I-G-V-K-K-E-P-W"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-E-Y-K-Q-C-I-V-T-R-D-D-L-K-L-S-K-G-K-F-A-V-Q-V-A-H-A-A-L-S-A-A-E-W-A-S-K-G-D-L-E-K-W-K-E-G-G-Q-K-K-I-V-L-K-V-P-S-I-K-E-L-Y-E-L-K-E-K-A-R-R-E-G-L-P-T-A-L-I-Q-D-A-G-L-T-E-I-P-P-G-T-V-T-V-L-G-I-G-P-A-K-E-E-L-I-D-K-I-T-K-D-L-K-L-V"} +{"text": "### FUNCTION Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs ### SEQUENCE -M-K-R-I-V-L-L-R-L-G-H-R-P-E-R-D-K-R-I-T-T-H-V-G-L-T-A-R-M-L-G-A-E-G-M-L-L-A-S-D-D-S-G-I-V-Q-S-L-E-D-V-V-R-R-W-G-G-N-F-Y-I-K-N-N-V-S-F-K-Q-E-I-R-N-W-K-E-G-G-G-K-V-C-H-L-S-M-Y-G-V-N-L-P-D-L-A-D-E-L-K-K-C-D-K-L-M-I-V-V-G-A-E-K-V-P-P-E-I-Y-Q-L-A-D-W-N-V-A-V-G-S-Q-P-H-S-E-V-A-A-V-A-I-T-M-D-R-I-A-E-G-E-P-L-E-K-E-F-P-G-A-E-L-T-I-V-P-A-E-R-G-K-H-V-I-E-N-A-G-E"} +{"text": "### FUNCTION Antimicrobial peptide ### SEQUENCE -M-F-T-L-K-K-S-L-L-L-L-F-F-L-G-T-I-S-L-S-L-C-Q-R-E-A-D-D-D-Q-G-E-V-Q-Q-E-V-K-R-G-F-L-S-T-V-K-N-L-A-T-N-V-A-G-T-V-I-D-T-I-K-C-K-V-T-G-G-C-R-K"} +{"text": "### FUNCTION Snake venom natriuretic peptide that exhibits hypotensive and vasodepressor activity Acts by activating natriuretic receptors ### SEQUENCE -E-V-K-Y-D-P-C-F-G-H-K-I-D-R-I-N-H-V-S-N-L-G-C-P-S-L-R-D-P-R-P-T-A-P-A-A-L-R-I-I-R-D-L-H-P-D-S-K-Q-S-Q-A-A"} +{"text": "### FUNCTION Receptor for both mineralocorticoids ### SEQUENCE -F-A-L-S-W-R-S-Y-K-H-T-N-S-Q-F-L-Y-F-A-P-D-L-I-F-D-E-E-R-M-R-Q-S-A-M-F-E-L-C-Q-G-M-H-Q-I-S-L-Q-F-V-R-L-Q-L-S-F-E-E-Y-T-I-M-K-V-L-L-L-L-S-T-V-P-K-D-G-L-K-S-Q-A-A-F-E-E-M-R-A-N-Y-I-K-E-L-K-K-M-V-T-K-C-P-S-N-S-G-Q-S-W-Q-R-F-Y-Q-L-T-K-L-L-D-S-M-H-D-L-V-S-D-L-L-E-F-C-F-Y-T-F-R-E-S-Q-A-L-K-V-E-F-P-A"} +{"text": "### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-N-S-L-S-I-F-F-I-V-V-A-T-A-A-V-C-L-L-F-I-Q-G-Y-S-I-Y-E-N-Y-G-N-I-K-E-F-N-A-T-H-A-A-F-E-Y-S-K-S-I-G-G-T-P-A-L-D-R-R-V-Q-D-V-N-D-T-I-S-D-V-K-Q-K-W-R-C-V-T-Y-P-G-N-G-F-V-S-A-S-V-F-G-F-Q-A-E-V-G-P-N-N-T-R-S-I-R-K-F-N-T-M-Q-Q-C-I-D-F-T-F-S-D-V-I-N-I-D-I-Y-N-P-C-V-A-P-N-I-N-N-A-E-C-Q-F-L-K-S-V-L"} +{"text": "### FUNCTION Glutaredoxin necessary for virion morphogenesis and virus replication Functions as a thiol-disulfide transfer protein between membrane-associated OPG128 and substrates OPG095 or OPG053 The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves oxidation of OPG072, OPG128 and OPG088 Exhibit thioltransferase and dehydroascorbate reductase activities in vitro ### SEQUENCE -M-K-N-V-L-I-I-F-G-K-P-Y-C-S-I-C-E-N-V-S-E-A-V-E-E-L-K-S-E-Y-D-I-L-H-V-D-I-L-S-F-F-L-K-D-G-A-S-S-M-L-G-D-V-K-R-G-T-L-I-G-N-F-A-A-H-L-S-N-Y-I-V-S-I-F-K-Y-N-P-Q-T-K-Q-M-A-F-V-D-I-N-K-S-L-D-F-T-K-T-D-K-S-L-V-N-L-E-I-L-K-S-E-I-E-K-A-T-Y-G-V-W-P-P-V-T-E"} +{"text": "### FUNCTION Has thioltransferase and dehydroascorbate reductase activities ### SEQUENCE -M-A-E-E-F-V-Q-Q-R-L-A-N-N-K-V-T-I-F-V-K-F-T-C-P-F-C-R-N-A-L-D-I-L-N-K-F-S-F-K-R-G-A-Y-E-I-V-D-I-K-E-F-R-P-E-N-E-L-R-D-Y-F-E-Q-I-T-G-G-R-T-V-P-R-I-F-F-G-K-T-S-I-G-G-Y-S-D-L-L-E-I-D-N-M-D-A-L-G-D-I-L-S-S-I-G-V-L-R-T-C"} +{"text": "### FUNCTION Involved in effecient integration of the N-module into mitochondrial respiratory chain complex I ### SEQUENCE -M-A-A-S-R-L-P-P-A-A-L-T-L-K-Q-F-M-R-R-Q-Q-V-L-L-L-Y-R-K-I-L-R-A-I-R-Q-V-P-S-D-S-D-R-K-Y-L-Q-D-W-A-R-E-E-F-K-R-N-K-S-A-T-E-E-D-T-I-R-M-M-I-T-Q-G-N-M-Q-L-K-E-L-E-R-T-L-A-L-A-N-S"} +{"text": "### FUNCTION Component of the anaphase promoting complex/cyclosome ### SEQUENCE -M-D-S-E-V-Q-R-D-G-R-I-L-D-L-I-D-D-A-W-R-E-D-K-L-P-Y-E-D-V-A-I-P-L-S-E-L-P-E-P-E-Q-D-N-G-G-T-T-E-S-V-K-E-Q-E-M-K-W-T-D-L-A-L-Q-G-L-H-E-N-V-P-P-A-G-N"} +{"text": "### FUNCTION May be involved in transcriptional regulation ### SEQUENCE -M-E-E-V-R-G-E-N-E-G-K-L-E-K-E-G-K-P-E-D-E-V-E-P-E-D-E-E-K-S-D-E-D-E-K-P-D-K-K-A-K-P-A-P-R-Q-G-K-P-E-E-E-A-K-P-D-E-Q-G-Q-D-E-G-K-P-E-K-Q-G-K-S-D-G-E-G-K-R-Q-G-E-S-K-P-D-S-Q-A-K-S-A-S-E-A-R-A-A-E-K-R-P-A-E-D-Y-V-P-R-K-A-K-R-K-T-D-R-G-T-D-D-S-P-K-N-S-Q-E-D-L-Q-D-R-H-V-S-S-E-E-M-M-R-E-C-A-D-M-T-R-A-Q-E-E-L-R-K-R-Q-K-M-G-G-F-H-W-V-P-R-D-A-Q-D-A-L-V-P-R-G-P-R-G-V-R-G-V-R-G-G-G-G-R-S-Q-R-G-L-H-D-I-P-Y-L"} +{"text": "### FUNCTION Has antibacterial activity ### SEQUENCE -M-P-Q-T-F-F-V-F-C-F-L-F-F-V-F-L-Q-L-F-P-G-T-G-E-I-A-V-C-E-T-C-R-L-G-R-G-K-C-R-R-A-C-I-E-S-E-K-I-V-G-W-C-K-L-N-F-F-C-C-R-E-R-I"} +{"text": "### FUNCTION Has antibacterial activity ### SEQUENCE -M-R-I-F-S-L-I-V-A-G-L-V-L-L-I-Q-L-Y-P-A-W-G-T-L-Y-R-R-F-L-C-K-K-M-N-G-Q-C-E-A-E-C-F-T-F-E-Q-K-I-G-T-C-Q-A-N-F-L-C-C-R-K-R-K-E-H"} +{"text": "### FUNCTION Has antibacterial activity ### SEQUENCE -M-R-T-L-C-S-L-L-L-I-C-C-L-L-F-S-Y-T-T-P-A-A-N-S-I-I-G-V-S-E-M-E-R-C-H-K-K-G-G-Y-C-Y-F-Y-C-F-S-S-H-K-K-I-G-S-C-F-P-E-W-P-R-C-C-K-N-I-K"} +{"text": "### FUNCTION May be essential for the survival of the neurosensory epithelium of the inner ear ### SEQUENCE -M-Q-A-C-V-L-W-W-L-A-L-G-M-L-L-G-I-P-A-G-A-K-P-M-P-E-E-A-D-P-H-T-Q-P-P-A-M-P-Y-W-P-F-S-T-S-D-F-W-N-Y-V-Q-Y-F-Q-T-Q-G-A-Y-P-Q-I-E-D-M-A-R-T-F-F-A-H-F-P-L-G-S-T-L-G-F-H-V-P-Y-Q-E-D"} +{"text": "### FUNCTION Endogenous activator of intestinal guanylate cyclase It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins May be a potent physiological regulator of intestinal fluid and electrolyte transport May be an autocrine/paracrine regulator of intestinal salt and water transport ### SEQUENCE -M-S-G-S-Q-L-W-A-A-V-V-V-L-L-L-L-Q-S-A-Q-G-V-Y-I-K-Y-H-G-F-Q-V-Q-L-E-S-V-K-K-L-S-E-L-E-E-K-Q-M-S-S-P-Q-L-R-K-S-G-L-L-L-P-D-V-C-H-N-P-A-L-P-L-D-L-Q-P-I-C-A-S-Q-E-A-A-S-T-F-K-A-L-R-T-I-A-T-D-E-C-E-L-C-I-N-V-A-C-T-G-C"} +{"text": "### FUNCTION Endogenous activator of intestinal guanylate cyclase It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins ### SEQUENCE -M-N-A-C-V-L-S-V-L-C-L-L-G-A-V-A-V-L-V-E-G-V-T-V-Q-D-G-D-L-S-F-P-L-E-S-V-K-Q-L-K-D-L-R-E-V-Q-E-P-R-L-A-S-H-K-K-F-A-P-R-L-L-K-P-V-A-P-Q-L-C-S-Q-S-A-F-P-E-A-L-R-P-L-C-E-K-P-N-A-E-E-I-L-Q-R-L-E-A-I-A-Q-D-P-N-T-C-E-I-C-A-Y-A-A-C-T-G-C"} +{"text": "### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate May function as an ADP-ribosylase ### SEQUENCE -M-D-N-D-V-K-L-G-R-F-I-S-L-I-L-R-H-K-P-E-T-I-N-L-K-L-D-K-N-G-W-A-N-T-K-E-L-I-E-K-I-S-K-S-G-R-E-I-D-F-E-I-L-E-R-I-V-N-E-N-N-K-K-R-Y-S-F-N-E-D-K-T-K-I-R-A-V-Q-G-H-S-I-E-V-N-L-E-L-K-E-V-V-P-P-A-I-L-Y-H-G-T-A-F-K-T-L-E-S-I-K-K-E-G-I-K-K-M-S-R-Q-H-V-H-L-S-A-D-I-E-T-A-K-N-V-A-T-R-H-S-G-K-Y-I-I-L-E-I-D-T-E-A-M-L-K-E-N-Y-K-F-Y-L-S-E-N-K-V-W-L-T-D-F-V-P-S-K-F-I-K-F"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-V-L-G-L-D-V-G-D-K-T-I-G-V-A-I-S-D-V-S-S-T-I-A-Q-G-I-T-T-I-R-R-K-S-F-V-E-D-V-K-A-I-E-E-I-V-K-K-Y-S-V-E-K-V-V-V-G-L-P-K-N-M-N-G-S-I-G-P-Q-G-E-K-V-I-K-F-G-E-K-L-R-E-V-L-R-I-P-V-V-F-W-D-E-R-L-T-T-L-Q-A-E-R-F-L-I-E-G-V-D-M-S-R-G-K-R-K-K-V-I-D-K-L-A-A-T-I-I-L-Q-S-Y-L-D-S-Q-K-N-S"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-R-L-K-P-L-G-D-R-V-V-V-K-V-I-Q-S-E-E-V-T-K-G-G-V-I-L-P-G-T-A-K-E-K-P-Q-Q-G-E-V-V-A-V-G-P-G-Q-Y-I-D-G-K-R-V-E-P-E-V-K-V-G-D-R-V-I-F-S-K-Y-A-G-T-E-V-K-L-D-G-E-E-Y-L-L-L-R-E-S-D-I-L-A-I-I-E"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-L-L-F-S-K-K-I-A-Q-H-K-G-G-I-C-L-E-G-I-V-R-F-G-V-S-M-E-S-K-L-L-K-Q-F-D-E-L-I-K-K-K-N-Y-N-N-R-S-E-A-I-R-D-L-I-R-D-F-I-V-E-N-Q-W-E-A-E-D-V-E-T-I-G-T-I-T-Y-V-F-N-H-E-V-R-E-I-N-D-K-L-T-D-M-Q-H-K-H-Y-K-N-I-I-S-T-M-H-V-H-L-D-E-H-N-C-I-E-V-M-I-V-R-G-K-A-K-E-I-V-K-I-A-D-E-I-I-S-T-R-G-V-K-H-G-K-L-V-M-T-T-T-G-E-N-L"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-K-D-V-I-E-L-E-G-T-I-V-E-A-L-P-N-A-M-F-K-V-E-L-E-N-G-H-T-I-L-G-H-I-S-G-K-M-R-M-N-Y-I-K-I-L-P-G-D-G-V-T-V-Q-I-S-P-Y-D-L-S-R-G-R-I-V-Y-R-K-K-N"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-E-L-I-V-D-F-S-S-D-L-Q-T-E-K-Y-N-M-F-I-D-T-L-Y-E-N-N-H-L-E-N-Y-I-K-K-V-L-N-L-E-K-I-E-S-D-R-P-L-Y-L-S-L-L-L-T-D-N-E-N-I-Q-V-I-N-R-E-Y-R-D-K-D-A-P-T-D-V-I-S-F-A-Y-H-E-T-E-D-F-N-I-G-S-Y-D-T-L-G-D-I-I-I-S-L-E-R-V-E-E-Q-A-S-E-Y-N-H-S-F-E-R-E-F-Y-Y-V-L-T-H-G-I-L-H-I-L-G-Y-D-H-I-E-E-E-D-K-K-L-M-R-E-R-E-E-A-I-L-S-S-F-G-Y-T-R-D-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-I-A-Q-E-L-R-A-G-S-T-I-K-I-G-N-D-P-F-V-V-L-K-A-E-Y-N-K-S-G-R-N-A-A-V-V-K-F-K-M-K-N-L-I-S-G-N-I-S-D-A-V-Y-K-A-D-D-K-M-D-D-I-K-L-D-K-V-K-A-I-Y-S-Y-Q-N-G-D-S-Y-I-F-S-N-P-E-T-W-E-E-I-E-L-K-G-E-D-L-G-D-A-L-N-Y-L-E-E-E-M-P-L-D-V-V-Y-Y-E-S-T-A-V-A-V-E-L-P-T-F-V-E-R-E-V-T-Y-T-E-P-G-L-R-G-D-T-S-G-K-V-M-K-P-A-R-I-N-T-G-F-E-V-Q-V-P-L-F-V-E-Q-G-E-W-I-K-I-D-T-R-T-N-E-Y-V-E-R-V-K-K"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-Y-F-R-T-G-F-C-L-F-Y-F-F-Q-W-R-C-S-V-I-S-D-K-T-R-I-N-E-K-I-R-G-K-E-F-R-I-I-S-F-D-G-E-Q-L-G-I-M-T-A-E-Q-A-L-N-L-A-S-S-Q-G-Y-D-L-V-E-I-A-P-S-A-T-P-P-V-C-K-I-M-D-Y-S-K-Y-K-Y-E-Q-T-R-K-L-K-E-A-K-K-N-Q-K-Q-V-V-I-K-E-I-K-V-T-A-R-I-D-S-H-D-L-E-T-K-L-N-Q-V-T-K-F-L-E-K-E-N-K-V-K-V-T-L-V-L-F-G-R-E-K-M-H-A-N-L-G-V-T-T-L-D-E-I-A-E-K-F-S-E-T-A-E-V-E-K-K-Y-A-D-K-Q-K-H-L-I-L-S-P-K-K-V-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-I-A-S-D-K-L-V-K-E-C-E-E-K-M-V-K-T-I-E-A-V-K-E-K-F-T-A-I-R-A-G-R-A-N-V-S-M-L-D-G-I-K-V-E-N-Y-G-S-E-V-P-L-N-Q-I-G-T-V-S-A-P-E-A-R-L-L-V-I-D-P-W-D-K-T-L-I-S-K-I-E-K-A-I-L-A-A-N-I-G-M-T-P-N-N-D-G-R-V-I-R-L-V-L-P-E-L-T-A-D-R-R-K-E-Y-V-K-L-A-K-N-E-A-E-N-G-K-I-A-I-R-N-I-R-K-D-I-N-N-H-L-K-K-L-E-K-D-K-E-N-P-I-S-E-D-E-L-K-K-E-E-T-N-V-Q-T-L-T-D-K-Y-V-K-E-I-D-D-L-L-A-K-K-E-K-E-I-T-T-I"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-F-C-S-S-E-D-T-K-V-V-D-S-R-T-T-I-D-G-S-T-K-R-R-R-E-C-N-N-C-L-K-R-F-S-T-Y-E-R-F-E-E-S-P-I-Y-V-V-K-K-D-N-R-R-V-K-Y-D-R-E-K-L-L-R-G-L-T-F-A-T-A-K-R-N-V-S-R-E-E-L-D-K-I-I-T-D-I-E-R-S-L-Q-N-S-L-I-S-E-I-S-S-K-D-L-G-E-K-V-L-E-K-L-R-E-L-D-Q-V-A-Y-V-R-F-A-S-V-Y-K-E-F-D-D-I-K-S-F-I-E-I-V-E-E-I-K-K-D"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-R-E-K-L-T-K-L-K-K-T-Q-E-F-K-R-V-Y-S-N-G-K-T-V-A-N-R-F-I-V-M-Y-Y-M-P-N-G-L-Q-V-N-R-A-G-Y-S-V-S-K-K-I-G-K-S-V-V-R-N-R-V-K-R-L-L-H-E-S-F-R-L-L-N-S-N-L-R-Q-G-Y-D-V-V-F-V-A-R-G-K-I-A-E-A-D-F-H-T-L-K-E-S-I-E-K-L-L-K-K-T-P-L-Y-E-E-K-E-R"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-S-Y-E-T-M-Y-V-L-S-P-D-L-N-E-E-E-R-K-G-L-I-E-R-F-K-N-L-I-V-E-R-G-G-E-I-T-N-F-D-E-W-G-K-R-K-L-A-Y-P-I-Q-K-K-S-E-G-Y-Y-V-L-M-N-F-N-S-S-P-D-V-S-R-E-L-E-R-V-Y-R-I-T-D-G-V-L-R-Y-L-I-I-R-T-D-D"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-L-N-K-V-I-L-I-G-R-L-T-K-D-P-V-M-R-Y-T-S-D-M-V-P-V-T-T-F-T-L-A-V-N-R-N-Y-V-S-Q-S-G-E-R-P-T-D-F-I-P-I-V-T-W-R-K-L-A-E-I-C-A-N-N-L-K-K-G-R-L-V-A-V-T-G-S-I-Q-T-R-T-W-D-D-S-S-G-N-R-H-W-V-T-E-V-V-A-D-D-V-R-F-L-E-P-K-S-G-F-G-S-G-S-A-P-E-E-E-K-E-L-D-E-D-F-D-K-L-F-E-D-I-P-D-D-F-D-G-F-T-P-I-E-S-E-D-D-L-P-F"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-T-T-A-N-T-N-E-T-A-A-A-A-A-A-K-N-R-R-N-K-K-K-K-R-V-C-A-F-C-A-D-N-I-D-R-I-D-Y-K-D-V-A-R-L-R-K-Y-I-T-E-R-G-K-I-L-P-R-R-I-T-G-N-C-A-R-H-Q-R-Q-L-T-K-A-I-K-R-A-R-Q-I-A-L-L-P-Y-T-V-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-V-K-D-V-K-N-V-G-K-A-G-E-V-V-N-V-S-D-G-Y-G-R-N-Y-L-I-P-K-G-L-A-I-E-A-T-E-S-N-L-K-M-L-N-E-K-K-K-A-E-E-R-K-R-Q-Q-E-L-E-Q-A-K-E-L-A-Q-K-L-S-K-V-G-V-T-L-K-V-K-A-G-E-N-G-K-L-F-G-S-V-T-S-K-D-V-E-E-A-L-K-E-K-G-F-E-I-D-K-K-K-I-V-L-P-E-N-I-K-T-T-G-T-Y-Y-A-E-I-K-L-Y-Q-G-V-T-A-K-V-Q-V-D-V-V-A-E"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-Q-I-I-A-V-G-T-I-K-E-N-Y-I-K-D-G-I-K-F-Y-L-D-K-L-K-K-I-Y-D-I-E-I-V-E-I-K-E-E-E-D-P-G-T-P-A-S-R-E-K-V-L-E-T-E-G-E-R-I-L-Y-K-I-D-R-E-S-F-V-I-A-L-A-I-E-G-K-E-V-S-T-E-E-F-A-S-L-V-K-K-A-F-G-M-G-Y-K-K-V-V-F-V-I-G-G-S-L-G-I-W-G-K-V-K-E-R-A-D-V-N-I-S-F-S-K-M-T-F-P-H-Q-L-T-R-L-L-L-L-E-Q-I-Y-Y-A-L-L"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-N-Y-K-F-F-I-I-A-K-K-I-E-P-F-Y-Q-E-A-I-E-E-Y-F-K-R-L-Q-R-F-C-S-I-S-L-S-I-C-K-N-S-K-K-L-P-V-K-D-L-E-K-S-Y-K-I-L-I-T-P-Q-G-K-T-I-S-S-E-K-F-A-L-K-I-K-D-L-E-M-K-S-I-T-D-I-T-F-L-I-G-E-G-I-E-I-F-D-E-I-F-T-I-S-Q-M-K-M-S-K-G-L-I-A-T-L-L-A-E-Q-L-Y-R-A-Y-K-I-L-R-N-E-P-Y-H-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-Y-I-I-A-G-L-G-N-P-G-K-E-Y-E-G-T-R-H-N-V-G-F-M-V-I-D-A-L-S-K-K-L-G-I-E-V-S-R-L-K-F-K-S-L-M-G-E-G-H-F-K-G-E-K-V-I-L-L-K-P-Q-T-F-M-N-L-S-G-E-A-L-Y-D-A-V-N-F-Y-K-I-P-L-E-N-V-I-V-V-Y-D-D-K-D-L-E-V-G-K-I-R-I-R-R-K-G-S-S-G-G-H-N-G-M-N-S-I-I-Y-L-L-N-S-E-D-F-P-R-V-R-I-G-I-G-K-P-E-D-G-D-L-V-R-H-V-L-G-R-F-S-D-E-E-K-K-V-I-D-E-A-V-E-R-A-A-E-A-V-I-D-I-M-E-N-G-I-E-H-A-M-S-R-F-N-G"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-K-P-V-I-L-T-Y-E-G-L-K-K-L-E-E-E-L-E-Y-L-K-T-V-K-R-A-E-V-A-E-K-I-K-Q-A-R-A-F-G-D-L-S-E-N-S-E-Y-D-E-A-K-N-E-Q-A-F-I-E-G-R-I-A-T-L-E-A-M-L-K-N-A-K-V-I-D-E-E-D-I-K-L-D-E-V-S-I-G-C-T-V-K-V-F-D-E-T-Y-N-E-E-V-E-Y-T-I-V-G-S-A-E-A-D-P-M-N-N-K-I-S-D-E-S-P-I-G-K-A-L-L-G-K-K-V-G-E-T-I-S-V-E-V-P-A-G-V-I-K-L-K-I-L-E-I-R-R"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-V-A-V-V-K-I-Q-L-P-A-G-K-A-T-P-A-P-P-V-G-T-A-L-G-P-H-G-V-N-I-M-A-F-C-K-E-F-N-E-R-T-A-K-D-A-G-L-I-I-P-V-V-I-T-I-Y-S-D-R-S-F-S-F-I-T-K-T-P-P-A-S-V-L-L-K-K-A-A-G-I-E-S-G-S-P-Q-P-N-K-Q-K-V-G-K-I-T-K-Q-Q-L-R-E-I-A-E-I-K-M-R-D-L-N-T-T-D-I-E-A-A-M-R-M-I-A-G-T-A-R-S-M-G-I-E-I-V"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-G-A-S-R-E-K-K-Q-Q-I-V-A-E-F-K-D-K-L-S-K-A-Q-T-V-I-F-T-S-F-S-G-L-T-V-E-D-E-T-V-L-R-R-K-F-K-E-A-N-S-E-Y-K-V-Y-K-N-T-L-M-T-I-A-A-R-E-L-G-Y-G-D-D-L-I-K-Y-F-E-G-P-T-S-V-A-F-G-Y-E-D-P-V-A-P-A-K-I-L-T-E-F-M-K-D-H-K-G-L-E-L-K-V-G-I-V-N-G-K-I-V-S-P-Q-E-I-E-A-L-A-K-L-P-S-R-E-E-L-L-A-K-A-L-G-S-M-K-A-P-I-T-N-L-V-F-V-L-S-G-T-L-R-S-L-V-Y-A-L-N-A-I-K-E-K-K-Q-A-E-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-K-E-E-I-L-Q-A-I-K-N-M-T-V-L-E-L-A-E-L-V-K-A-L-E-E-E-F-G-V-S-A-A-A-P-V-A-V-A-A-A-P-A-A-G-A-P-A-A-A-P-A-E-E-K-T-E-F-D-V-I-L-Q-E-V-G-S-D-K-I-K-V-I-K-V-V-R-E-I-T-G-L-G-L-K-E-A-K-D-L-V-D-S-V-P-K-P-I-K-E-G-V-S-K-E-E-A-N-Q-I-K-A-K-F-E-E-V-G-A-K-V-E-I-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-V-N-Q-L-V-R-F-G-R-Q-S-V-K-K-K-S-A-A-P-A-L-Q-G-N-P-Q-K-R-G-V-C-V-V-V-R-T-T-T-P-K-K-P-N-S-A-L-R-K-I-A-R-V-R-L-T-N-G-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-K-I-I-R-G-A-L-D-A-A-G-V-A-N-R-K-Q-A-R-S-R-Y-G-A-K-K-P-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-P-K-R-E-V-L-P-D-P-V-Y-N-S-V-K-V-A-K-L-I-N-K-V-M-W-D-G-K-K-S-L-A-Q-K-I-C-Y-G-A-F-D-I-I-R-E-K-T-G-R-D-P-L-E-V-F-E-E-A-L-N-N-V-M-P-V-L-E-V-R-P-R-R-V-G-G-A-T-Y-Q-V-P-M-E-V-R-P-E-R-R-L-S-L-G-I-R-W-I-V-E-Y-A-R-Q-R-S-G-K-S-M-M-E-K-L-A-A-E-I-I-D-A-A-N-N-T-G-G-S-V-K-K-K-E-D-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-P-K-Q-K-I-R-I-R-L-K-A-F-D-H-A-I-L-D-Q-S-A-Q-K-I-V-E-T-A-K-R-T-G-A-E-V-S-G-P-I-P-L-P-T-K-R-E-V-I-T-I-L-R-A-P-H-K-Y-K-D-S-R-E-Q-F-E-I-K-T-H-K-R-L-I-D-I-L-N-P-T-P-K-T-V-D-A-L-M-K-L-D-L-P-S-G-V-D-I-E-I-K-L"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-E-A-R-D-I-I-I-R-P-V-I-T-E-K-S-M-N-L-M-G-D-R-K-Y-T-F-I-V-D-K-R-A-N-K-I-E-I-K-K-A-V-E-E-I-F-G-V-K-V-E-K-V-Y-T-M-N-Y-K-G-K-P-K-R-M-G-K-Y-E-G-R-T-E-S-Y-K-K-A-I-V-K-L-A-P-D-S-K-G-I-E-F-F-E-G-L-Q"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-V-K-K-G-P-F-V-D-P-K-L-L-K-K-I-I-E-M-N-K-K-N-E-K-K-V-I-K-T-W-S-R-D-S-T-I-V-P-E-M-V-G-H-T-I-A-V-H-D-G-R-K-H-V-P-V-Y-I-T-E-A-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-R-G-H-A-G-S-E-K-T-T-K-V-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-R-A-I-A-R-Y-V-R-I-S-P-R-K-A-R-L-V-L-N-L-I-R-G-K-H-V-D-E-A-L-A-I-L-K-F-T-P-K-K-A-S-K-I-V-E-K-V-L-K-S-A-I-A-N-A-E-N-N-H-N-M-N-R-D-N-L-Y-V-A-K-A-V-A-D-E-G-P-T-M-K-R-V-L-P-R-A-M-G-R-A-D-I-M-R-R-R-T-S-H-I-T-I-V-V-K-E-K-E-E"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-Y-R-K-Q-Q-R-G-R-I-K-G-N-A-T-R-G-N-T-L-T-Y-G-E-Y-G-L-Q-A-L-E-P-G-W-I-T-A-T-Q-I-E-A-A-R-V-A-M-T-R-Y-I-K-R-G-G-K-V-W-I-K-I-F-P-D-K-P-V-T-K-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-F-W-V-A-V-V-K-P-G-R-V-L-F-E-I-G-G-V-S-E-D-V-A-K-E-A-L-R-L-A-M-H-K-L-P-I-K-T-K-F-L-K-R-E-E-L-G-G-E-S-N-E-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-G-Q-R-K-V-R-I-G-T-V-V-S-N-K-M-Q-K-T-I-V-V-A-V-E-D-K-F-R-H-P-L-Y-G-K-I-V-K-R-T-K-K-Y-K-V-H-D-E-N-N-I-C-N-V-G-D-V-V-K-I-M-E-T-R-P-L-S-K-E-K-R-W-R-L-V-E-V-I-K-K-A-E"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-R-P-Q-T-R-L-K-V-A-D-N-T-G-A-K-E-I-M-C-I-R-L-L-G-G-S-N-R-K-Y-S-N-V-G-D-I-I-V-A-S-V-K-S-A-T-P-G-G-V-V-K-K-G-E-V-V-K-A-V-I-V-R-T-K-K-G-I-A-R-K-D-G-T-Y-I-R-F-D-D-N-A-A-V-I-I-R-D-D-K-Q-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-K-D-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-Q-N-K-L-H-V-K-K-G-D-M-V-V-V-I-S-G-K-D-K-G-K-K-G-R-V-L-Q-A-F-P-K-E-G-K-V-I-V-E-G-V-N-V-V-T-K-H-R-K-A-T-R-P-Q-K-P-G-G-I-I-H-Q-E-A-P-I-H-S-S-K-V-M-L-Y-C-E-N-C-G-R-G-V-R-Y-G-I-K-I-L-E-N-G-E-K-V-R-Y-C-K-R-C-N-E-T-L"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-R-L-R-E-K-Y-E-K-E-V-V-P-A-L-M-E-R-F-G-Y-K-N-I-M-Q-V-P-K-L-E-K-V-V-I-N-I-G-V-G-E-A-K-E-N-P-K-A-L-E-A-A-M-N-D-L-M-M-I-S-G-Q-K-P-V-I-T-R-A-K-K-S-I-S-N-F-K-I-R-K-G-M-P-I-G-V-K-V-T-L-R-R-E-R-M-Y-E-F-L-D-K-L-F-N-I-A-L-P-R-V-R-D-F-K-G-V-S-P-N-S-F-D-G-R-G-N-Y-A-L-G-V-R-E-Q-L-I-F-P-E-I-D-Y-D-K-I-D-K-V-R-G-M-D-I-I-I-V-T-T-A-K-T-D-E-E-A-K-A-L-L-E-L-L-G-M-P-F-A-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-R-K-A-L-I-V-K-Q-Q-K-P-Q-K-Y-K-T-R-E-Y-N-R-C-K-I-C-G-R-P-R-A-Y-L-R-K-F-G-M-C-R-L-C-F-R-K-Y-A-H-Q-G-M-I-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-M-L-T-R-I-R-N-A-N-L-A-R-H-E-T-V-E-I-P-S-S-K-M-K-K-A-I-A-M-I-L-L-K-E-G-F-V-K-A-V-E-E-I-D-D-G-K-G-G-I-L-K-I-T-L-K-Y-G-P-N-K-E-R-V-I-S-G-L-K-R-I-S-K-P-G-L-R-V-Y-A-K-H-D-E-L-P-R-V-L-G-G-L-G-I-A-I-I-S-T-S-K-G-I-M-T-D-K-E-A-R-K-A-G-L-G-G-E-V-I-C-Y-V-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-R-L-P-I-P-I-P-K-G-V-E-V-K-V-S-P-D-N-V-V-T-V-K-G-A-K-G-T-L-E-K-K-F-P-P-I-V-N-I-E-V-R-D-G-E-V-V-V-T-R-K-G-D-D-K-E-E-R-A-M-H-G-T-T-R-A-I-I-A-N-M-V-K-G-V-T-E-G-F-E-K-A-L-E-I-V-G-V-G-Y-R-A-A-K-Q-G-K-K-L-I-L-N-V-G-Y-S-H-P-V-E-I-E-E-E-P-G-I-E-I-I-V-E-G-N-N-R-I-I-V-R-G-A-D-K-E-R-V-G-Q-V-A-A-N-I-R-R-V-R-E-P-D-A-Y-Q-G-K-G-I-R-Y-V-G-E-V-V-R-L-K-E-G-K-T-G-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-I-K-P-S-R-N-E-L-R-K-K-R-H-L-R-V-R-K-K-V-F-G-T-P-E-R-P-R-L-N-V-Y-K-S-L-K-H-I-Y-A-Q-I-I-D-D-T-K-G-H-T-L-V-S-A-S-T-L-D-P-E-L-R-D-V-A-K-G-A-N-K-Q-S-A-K-L-V-G-E-L-I-A-K-R-A-L-E-K-G-I-K-D-V-V-F-D-R-G-G-Y-L-Y-H-G-V-V-K-E-L-A-D-A-A-R-Q-A-G-L-N-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-R-V-D-W-T-K-L-N-L-K-E-R-V-V-S-I-N-R-V-S-K-V-V-K-G-G-K-N-F-R-F-S-V-T-V-V-V-G-D-P-D-K-G-Y-V-G-V-G-R-G-K-A-A-E-I-P-D-A-I-R-K-A-I-E-D-A-K-K-H-L-I-K-V-P-V-V-G-T-T-I-P-H-E-V-I-G-E-F-G-A-G-K-V-L-L-K-P-A-R-E-G-T-G-V-I-A-G-G-P-V-R-A-V-L-E-S-A-G-I-R-D-V-L-S-K-S-L-G-S-S-N-A-T-N-M-V-Y-A-T-I-E-G-L-K-R-L-K-T-A-E-E-V-A-R-L-R-G-I-P-V-H-Q-L-F-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-H-D-L-K-P-A-E-G-S-T-K-K-K-K-R-V-G-R-G-I-G-S-G-H-G-K-T-S-G-R-G-H-K-G-Q-N-A-R-S-G-G-G-V-R-P-G-F-E-G-G-Q-M-P-L-T-R-R-I-P-K-R-G-F-T-N-I-F-K-K-E-Y-A-I-V-N-V-G-T-L-E-E-R-F-E-D-G-A-E-I-T-P-E-V-L-I-E-K-G-I-I-K-D-V-K-D-G-V-K-I-L-G-D-G-E-L-T-K-K-L-T-V-K-A-H-K-F-S-Q-S-A-V-E-K-I-Q-A-V-G-G-K-A-E-V-I"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-E-V-E-G-T-V-I-E-A-L-P-N-A-M-F-Q-V-Q-L-D-N-G-H-K-V-L-A-H-V-S-G-K-L-R-M-N-F-I-R-I-L-P-G-D-R-V-K-V-E-L-S-P-Y-D-L-T-R-G-R-I-V-W-R-G-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-L-P-R-D-K-R-V-E-I-A-L-T-Y-I-Y-G-I-G-R-S-R-S-K-E-I-L-A-K-A-G-V-N-P-D-T-R-V-R-D-L-T-E-D-E-V-S-K-L-R-E-I-I-E-K-E-Y-K-V-E-G-D-L-R-K-E-V-A-M-N-I-K-R-L-I-D-I-G-C-Y-R-G-I-R-H-K-L-G-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-K-T-V-A-K-K-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-R-V-K-R-A-G-R-K-R-E-K-K-H-V-E-R-G-I-A-H-I-H-S-T-F-N-N-T-I-V-T-I-T-D-P-A-G-N-T-I-A-W-A-S-A-G-T-V-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-S-A-A-K-A-A-M-D-H-G-M-R-T-V-D-V-Y-V-K-G-P-G-A-G-R-E-A-A-I-R-A-L-Q-A-A-G-L-E-V-S-L-I-K-D-V-T-P-I-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-S-Y-M-A-K-P-S-D-V-E-R-K-W-F-V-I-D-A-E-G-K-V-L-G-R-L-A-S-Q-I-A-K-I-L-M-G-K-H-K-P-T-Y-T-P-H-V-D-T-G-D-F-V-V-V-I-N-A-D-K-V-V-L-T-G-K-K-L-E-D-K-Y-Y-K-Y-Y-T-G-Y-P-G-G-L-K-Q-I-Q-Y-K-K-L-M-Q-T-K-P-E-F-V-I-Y-H-A-V-K-G-M-L-P-K-N-R-L-G-R-R-M-I-K-R-L-K-V-Y-R-G-A-E-H-K-H-Q-A-Q-K-P-E-K-L-D-I-E"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-E-I-F-V-G-T-D-I-M-E-V-E-R-I-K-K-I-L-E-K-R-P-H-F-L-E-R-I-F-T-E-K-E-R-E-F-L-R-K-K-K-N-P-W-P-H-L-A-G-F-F-S-A-K-E-S-V-S-K-V-L-G-T-G-I-R-G-F-S-W-Q-D-I-E-I-I-H-N-E-Y-G-K-P-E-V-V-L-K-G-K-A-K-A-I-A-A-E-K-G-I-K-E-I-K-L-S-I-S-H-T-S-D-Y-A-M-S-V-A-I-A-V-G-G-E-N-S"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-G-E-E-I-K-R-T-I-K-F-T-L-V-F-M-V-L-L-G-L-V-Y-P-F-V-M-T-G-I-A-N-L-L-F-P-Y-Q-A-K-G-S-I-I-K-V-D-G-K-P-V-G-S-E-L-I-G-Q-K-F-T-D-P-R-W-F-M-G-R-P-S-A-V-D-Y-D-A-T-S-S-G-G-T-N-Y-A-L-S-N-P-K-F-H-E-E-L-E-K-N-I-E-E-F-L-K-K-N-P-G-V-K-R-S-E-I-P-A-D-I-V-T-S-S-G-S-G-L-D-P-H-I-S-P-K-A-A-Y-L-Q-V-K-R-V-A-K-V-N-G-L-P-E-E-V-V-K-K-L-V-D-K-N-I-E-G-R-F-L-G-L-F-G-E-P-R-V-N-V-L-K-L-N-L-S-L-L-E-E-I-K-K-H-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-Q-A-I-T-L-E-A-V-K-R-E-T-G-K-S-A-A-R-R-L-K-N-Q-G-Y-V-P-A-I-M-Y-G-K-D-M-T-E-N-I-P-L-A-V-E-Y-T-K-L-Q-K-L-L-Q-K-Y-G-R-N-V-L-L-N-V-V-V-N-G-T-T-H-T-A-L-I-K-E-I-Q-E-D-T-L-K-G-K-I-I-H-V-D-F-Q-R-V-S-M-Y-E-E-I-E-A-T-V-P-L-R-F-E-G-I-G-L-I-E-S-K-G-G-I-V-Q-H-Q-L-W-E-L-T-V-E-S-L-P-D-K-I-P-Q-E-I-V-V-D-L-S-H-L-E-I-G-D-T-L-F-V-K-D-I-P-V-P-E-G-V-K-V-L-D-D-P-E-E-I-V-V-S-I-L-V-P-K-E-A-G-E-E-E-E-E-E-G-E-G-T-A-E-G"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-I-I-F-R-R-C-V-F-I-N-H-R-D-F-Q-V-N-E-Q-I-R-D-K-E-V-R-L-I-D-Q-D-G-K-Q-I-G-I-M-S-A-K-E-A-Y-K-I-A-Q-E-R-H-L-D-L-V-K-I-V-P-N-A-N-P-P-V-C-K-L-M-D-F-G-K-Y-R-Y-E-L-S-K-R-E-K-E-A-K-K-K-Q-K-I-I-N-V-K-E-I-R-M-S-P-N-I-E-D-H-D-F-G-V-K-L-K-S-A-I-K-F-L-K-D-G-D-K-V-K-V-T-I-R-F-R-G-R-E-A-A-H-T-S-L-A-E-D-L-L-K-R-F-A-E-E-L-R-E-Y-G-N-V-E-K-A-P-S-M-D-G-R-N-M-M-M-V-I-A-P-K-K-Q"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-S-G-K-V-T-R-R-R-H-K-K-I-L-K-L-A-K-G-Y-W-G-A-K-S-K-L-F-R-V-A-N-Q-A-V-M-K-S-L-M-Y-A-Y-I-G-R-K-L-R-K-R-D-F-R-R-L-W-I-T-R-I-N-A-A-A-R-A-Y-G-I-S-Y-S-R-F-I-N-G-L-K-K-A-G-I-E-I-N-R-K-M-L-S-E-M-A-I-H-D-E-K-A-F-A-E-L-V-N-I-A-K-Q-Q-L-N-A"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-Y-C-G-Y-P-D-S-R-V-I-D-S-R-P-T-D-D-N-T-A-I-R-R-R-R-E-C-L-K-C-G-K-R-F-T-T-Y-E-K-V-E-Q-L-P-I-L-V-I-K-K-D-N-R-R-E-L-Y-D-K-E-K-I-L-R-G-M-I-K-A-C-E-K-R-P-V-P-I-K-V-L-E-E-I-T-D-E-I-D-R-K-I-V-N-S-M-V-R-E-I-T-S-A-E-I-G-E-M-V-M-E-K-L-K-S-V-D-E-V-A-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-I-N-T-F-M-D-E-L-K-K-L-L-K-E-N-E-E-K-K-Q-K-E"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-S-K-V-I-D-K-I-M-S-F-L-G-I-E-E-E-E-E-E-I-Q-T-P-Q-P-V-V-S-Y-D-R-R-P-K-V-V-N-I-H-T-N-P-Q-I-K-V-L-I-S-K-P-E-K-F-E-Q-V-L-S-I-C-N-E-L-K-S-K-K-P-V-I-V-D-L-Q-K-M-D-K-S-E-A-Q-R-V-V-D-F-L-S-G-A-V-Y-A-L-N-G-E-I-T-K-I-S-G-Y-I-F-L-V-A-P-E-N-F-D-V-T-G-D-I-K-E-E-V-N-A-L-Y-N-L-N"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-R-V-K-A-E-I-M-D-E-K-A-I-D-R-A-L-I-R-I-A-H-E-I-V-E-R-N-K-G-I-E-D-V-V-L-V-G-I-K-T-R-G-V-P-L-A-K-R-I-A-R-Y-I-S-R-I-E-G-K-E-P-P-V-G-S-L-D-I-T-L-Y-R-D-D-L-T-T-D-L-E-Q-P-V-V-K-K-K-D-I-G-V-D-V-A-N-K-I-V-V-L-V-D-D-V-I-Y-T-G-R-T-V-R-A-A-M-D-A-I-I-D-L-G-R-P-K-A-I-Q-L-A-E-L-V-D-R-G-H-R-E-L-P-I-R-P-D-Y-V-G-K-N-V-P-T-S-R-S-E-I-I-Q-V-M-L-E-E-V-D-G-V-N-K-V-V-I-T-E-K"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-I-L-Y-P-S-I-V-D-L-M-E-K-V-D-S-K-Y-T-L-C-A-L-V-A-K-R-A-R-Q-L-V-A-G-D-K-K-L-V-D-I-D-S-D-K-P-V-T-I-A-T-E-E-V-Y-R-G-L-I-T-Y-E-R-P-Q-K-Y-G-I-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-I-R-Y-I-R-K-I-G-D-P-V-L-R-K-K-A-K-P-V-T-E-I-N-S-H-I-I-T-I-L-E-D-M-A-E-T-M-Y-L-N-D-G-V-G-L-A-A-N-Q-V-G-I-L-R-R-L-V-V-I-D-V-G-E-G-L-L-E-L-I-N-P-E-I-V-Y-E-E-G-E-Q-I-G-P-E-G-C-L-S-I-P-G-V-F-G-E-V-K-R-P-Q-K-V-K-V-R-Y-L-D-R-E-G-N-V-K-E-I-V-G-E-D-L-L-A-R-A-L-C-H-E-I-D-H-L-E-G-V-L-F-V-D-K-V-I-R-F-L-D-K-E-E-L-E-G-V-K-E-V"} +{"text": "### FUNCTION Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism ### SEQUENCE -M-A-V-R-V-S-K-A-E-R-Q-R-L-L-R-E-K-I-N-E-N-P-F-Y-T-D-D-E-L-A-D-M-F-G-V-S-V-Q-T-I-R-L-D-R-M-E-L-G-I-P-E-V-R-E-R-I-K-N-V-A-E-E-N-Y-R-K-V-K-T-I-L-G-A-E-V-V-G-E-L-I-D-L-E-L-G-K-R-G-I-S-I-F-E-P-T-E-D-M-V-F-V-K-T-K-I-V-K-G-Q-Y-I-Y-S-Q-A-E-S-L-A-L-S-L-I-D-A-P-A-A-L-I-G-V-A-N-I-K-Y-K-Y-P-V-K-V-G-D-R-L-V-A-K-A-E-V-I-R-Q-R-G-N-K-Y-F-V-W-V-K-I-K-V-K-E-K-E-V-F-R-G-K-F-I-L-V-A-L-E-E-D-F-L-K-K-R-S-D-T-V-E-V-G-N"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-I-F-E-K-V-R-N-I-I-A-E-Q-L-G-I-D-P-E-E-I-T-M-E-S-S-F-I-D-D-L-G-A-D-S-L-D-I-V-E-L-I-M-A-L-E-E-E-F-D-I-E-I-P-D-E-D-A-E-K-I-K-T-V-G-D-V-V-E-Y-L-S-N-I-V-E"} +{"text": "### FUNCTION A probable RNA chaperone Forms a complex with KhpB which binds to cellular RNA and controls its expression Plays a role in peptidoglycan homeostasis and cell length regulation ### SEQUENCE -M-G-E-L-V-K-T-I-A-K-A-L-V-D-N-P-D-A-V-E-V-N-E-I-H-G-H-Q-S-I-I-I-E-L-K-V-A-P-E-D-M-G-K-V-I-G-K-Q-G-R-I-A-Q-A-I-R-T-L-V-K-A-A-A-L-K-E-K-K-R-V-I-V-E-I-I"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-A-D-Y-Y-N-V-G-K-V-T-S-P-H-G-I-R-G-E-I-K-V-Y-P-L-T-N-V-P-E-R-F-Y-D-I-P-Y-I-W-V-F-D-E-K-D-I-P-C-K-Y-E-I-E-N-V-K-I-T-S-K-G-M-V-L-L-K-L-K-G-I-D-S-R-N-D-A-E-K-L-K-G-L-F-L-K-V-D-A-E-N-A-L-K-L-E-E-D-E-Y-F-I-T-D-L-I-G-M-K-V-Y-T-E-E-G-E-L-I-G-T-L-E-E-V-L-Q-T-G-A-N-D-V-Y-V-V-K-A-K-E-R-E-V-L-L-P-A-I-K-E-V-I-K-K-V-D-V-E-G-K-V-M-I-V-R-L-L-E-G-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-D-L-I-K-A-V-E-S-E-Q-L-K-K-D-I-T-P-F-N-V-G-D-T-V-R-V-Y-Y-K-V-I-E-G-D-R-E-R-I-Q-P-F-E-G-I-V-I-K-R-S-G-S-G-L-R-E-T-F-T-V-R-R-V-S-Y-G-V-G-V-E-R-T-F-P-L-H-S-P-R-L-E-K-I-E-V-I-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-K-R-V-G-K-A-A-T-K-I-K-E-L-M-E"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-E-S-K-I-L-R-V-G-M-A-D-A-K-V-T-K-S-P-G-I-L-T-T-I-G-L-G-S-C-V-G-I-V-L-Y-D-P-I-A-K-V-A-G-L-V-H-I-M-L-P-Y-S-N-K-I-S-D-N-S-N-K-L-K-F-A-D-T-G-I-E-I-L-I-E-E-M-L-K-E-G-A-N-P-K-R-L-I-S-K-L-A-G-G-A-Q-M-F-S-S-K-I-N-S-D-I-M-N-I-G-E-R-N-V-I-A-T-K-E-V-L-K-K-L-G-I-P-I-V-A-E-D-T-G-G-N-Y-G-R-T-I-E-F-Y-S-E-D-G-R-L-L-V-K-T-I-G-H-G-V-K-Y-I"} +{"text": "### FUNCTION Associates with the EF-TuGDP complex and induces the exchange of GDP to GTP It remains bound to the aminoacyl-tRNAEF-TuGTP complex up to the GTP hydrolysis stage on the ribosome ### SEQUENCE -M-I-S-A-Q-A-V-K-E-L-R-E-R-T-G-A-G-M-M-D-C-K-N-A-L-I-E-A-N-G-D-I-E-K-A-I-D-I-L-R-E-K-G-L-A-A-A-A-K-K-A-G-R-T-A-N-E-G-L-V-E-A-Y-I-H-G-G-G-R-I-G-V-L-V-E-V-N-C-E-T-D-F-V-A-N-T-E-E-F-R-N-F-V-K-E-I-C-M-Q-I-A-A-A-N-P-K-Y-I-S-K-E-D-V-P-Q-E-V-L-E-K-E-K-E-I-L-R-A-Q-A-L-N-E-G-K-P-A-N-V-I-D-R-I-V-E-G-R-L-E-K-F-Y-K-E-N-C-L-L-E-Q-E-Y-I-R-D-P-E-K-T-V-K-D-L-L-N-E-M-I-A-K-L-G-E-N-I-V-I-R-R-F-A-R-F-E-R-G-E-G-I-E-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-D-Y-L-K-D-S-E-E-R-M-K-K-T-L-N-V-L-K-S-E-L-A-A-I-R-A-G-R-A-N-P-A-L-L-D-R-I-T-V-N-Y-Y-G-T-P-T-P-L-N-R-L-A-T-I-T-A-P-E-P-R-V-L-V-V-Q-P-W-D-V-S-Q-I-G-E-I-E-K-A-I-Q-K-S-D-L-G-I-N-P-V-S-D-G-K-V-L-R-L-V-L-P-E-L-T-E-E-R-R-K-E-L-V-K-L-V-H-K-K-A-E-E-A-R-I-A-V-R-Q-I-R-R-D-A-N-D-L-V-K-K-M-E-K-D-G-E-I-S-E-D-E-R-K-R-R-E-E-E-I-Q-K-L-T-D-K-Y-I-K-E-I-D-K-M-V-E-A-K-E-K-E-I-M-E-I"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-R-I-E-E-I-T-K-E-L-V-M-P-I-L-E-E-N-N-F-E-L-V-D-V-E-Y-K-K-E-G-K-H-W-Y-L-R-V-Y-I-D-K-E-G-G-I-T-L-D-D-C-Q-L-V-S-E-Y-L-S-D-R-L-D-E-V-D-P-I-D-H-S-Y-I-L-E-V-S-S-P-G-L-D-R-P-L-K-T-P-R-D-F-K-R-N-L-G-K-E-V-E-V-S-L-Y-Q-P-I-D-K-R-K-K-F-T-G-E-L-L-E-F-T-G-D-K-I-I-L-L-C-E-G-E-K-R-E-F-E-M-K-N-V-R-L-V-K-P-V-I-K-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-R-K-M-Q-Y-R-S-H-R-L-S-E-E-L-K-K-E-I-S-K-M-I-L-E-E-I-K-D-P-R-I-K-A-M-V-S-I-T-D-I-E-V-T-K-D-L-R-Y-A-K-V-Y-V-S-I-Y-G-S-E-E-E-K-R-E-T-F-E-G-L-K-S-A-A-G-Y-I-R-H-E-I-G-R-R-I-K-M-R-Y-T-P-E-I-I-F-E-L-D-H-S-I-E-Y-G-A-K-I-S-E-I-L-K-E-L-N-K-Q-E-G-D-D-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-L-D-K-E-K-K-A-E-I-I-N-K-F-K-L-H-E-T-D-T-G-S-P-E-V-Q-I-A-L-L-T-E-R-I-N-R-L-T-E-H-L-Q-V-H-K-K-D-H-H-S-R-R-G-L-L-K-M-V-G-Q-R-R-A-L-L-N-Y-L-M-K-K-D-I-N-R-Y-R-A-I-I-E-K-L-D-L-R-K"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-S-I-V-L-K-I-K-R-T-E-D-A-K-D-L-P-L-P-A-Y-M-S-E-G-A-A-G-M-D-L-Y-A-N-V-K-G-E-V-T-I-N-P-G-E-V-E-L-I-P-T-G-I-Q-I-E-L-P-P-N-Y-E-A-Q-I-R-P-R-S-G-L-A-L-N-Y-G-I-T-L-L-N-T-P-G-T-V-D-S-D-Y-R-G-E-I-K-L-I-V-I-N-L-G-K-Q-P-V-T-I-K-R-G-Q-R-I-A-Q-M-V-I-N-Q-V-V-R-P-K-I-I-E-V-E-E-L-S-E-T-E-R-M-D-R-G-F-G-H-T-G-V"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-L-I-T-R-I-I-K-R-E-K-S-S-K-Y-D-V-F-I-D-G-E-Y-A-F-T-C-D-A-E-T-F-F-M-L-G-I-E-E-G-K-E-I-T-S-E-Q-Y-K-Y-Y-V-N-Y-I-E-A-K-E-A-K-N-H-A-F-R-L-L-S-R-K-M-L-T-E-K-Q-L-A-D-K-L-K-L-K-G-F-S-E-E-A-I-G-E-A-V-S-K-A-K-E-Y-D-Y-V-N-D-E-N-Y-A-K-F-F-V-E-E-K-M-Q-S-L-Y-S-R-R-R-I-Y-Y-E-L-L-K-R-G-V-E-K-E-I-I-E-K-V-L-E-S-I-Y-P-H-E-K-E-V-E-V-I-R-Q-I-V-E-K-K-K-N-S-H-R-E-I-Q-K-L-K-K-Y-L-Y-T-N-G-F-E-I-E-N-I-E-K-A-L-N-L-T"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-S-S-K-A-A-I-N-L-Q-D-I-F-L-N-Q-V-R-K-E-H-V-P-V-T-V-Y-L-I-N-G-F-Q-L-K-G-T-V-K-G-F-D-N-F-T-V-V-L-E-S-E-S-K-Q-Q-L-L-I-Y-K-H-A-I-S-T-I-S-P-Q-K-P-V-I-F-S-G-S-E-K-D-D-K-K-E-E"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-T-Q-E-G-K-I-E-A-I-L-F-A-A-G-Q-A-V-K-I-R-T-L-A-E-A-L-E-V-T-E-E-E-V-R-E-L-L-K-R-L-K-E-E-Y-V-K-N-H-R-G-I-D-I-V-I-F-E-D-K-V-E-M-C-T-N-D-S-Y-G-D-I-V-R-K-A-L-K-M-E-I-T-Q-G-L-S-Q-A-A-L-E-V-L-A-I-I-A-Y-N-Q-P-I-T-K-A-E-I-E-R-I-R-G-V-R-S-D-K-P-I-N-T-L-L-E-Y-N-L-I-K-E-S-G-R-A-S-S-P-G-R-P-I-L-Y-S-T-T-E-D-F-L-K-Y-F-G-I-S-S-L-K-E-L-P-E-I-E-P-T-S"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-M-K-L-A-R-H-A-K-I-L-E-I-I-S-E-K-E-I-E-T-Q-E-E-L-A-A-E-L-Q-K-R-G-I-D-V-T-Q-A-T-V-S-R-D-I-K-E-L-R-L-I-K-V-L-T-E-D-G-K-R-Y-K-Y-A-P-M-T-K-V-D-T-N-I-S-E-R-L-M-T-L-L-S-E-S-I-V-N-V-D-Y-A-G-N-I-I-V-I-K-T-L-S-G-S-A-S-A-A-A-E-A-I-D-T-L-N-W-K-N-I-V-G-T-I-A-G-D-N-T-I-F-V-L-V-R-N-Q-E-D-I-Q-E-L-V-E-K-F-R-K-L-M-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-E-K-E-F-N-F-E-E-D-L-K-R-L-E-E-I-V-D-T-L-E-K-G-N-L-M-L-E-E-S-F-N-L-F-K-E-G-V-E-I-S-K-R-L-E-K-M-L-K-E-V-E-G-K-I-T-M-L-I-S-E-D-E-E-I-E-F-K-E-E-E-N-N-V"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-N-R-T-E-A-R-E-W-V-V-K-M-L-Y-Q-Y-D-V-S-K-L-P-L-E-K-I-F-E-N-F-Y-E-E-H-D-P-G-E-Q-K-E-Y-I-E-G-T-V-R-G-T-V-E-H-L-E-E-I-D-R-E-I-E-K-Y-S-K-D-W-P-L-Y-R-M-P-R-I-D-L-A-I-L-R-C-S-M-Y-E-M-L-Y-G-N-I-P-V-S-I-S-I-N-E-A-V-E-I-A-K-K-Y-S-T-D-D-S-P-S-F-I-N-G-L-L-G-A-F-V-R-E-K-G-L-E-E-G-E-A-N-D-N"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-A-A-G-D-F-R-K-G-V-T-I-E-V-D-G-Q-I-F-T-V-V-D-F-M-H-V-K-P-G-K-G-A-A-F-V-R-T-K-L-K-N-I-M-T-G-A-V-I-E-R-T-F-S-P-T-E-K-F-E-E-A-Q-I-E-R-R-E-M-Q-Y-L-Y-N-D-G-E-F-Y-Y-F-M-D-T-E-T-Y-E-Q-I-P-L-S-Y-D-K-V-E-E-A-M-K-Y-I-K-E-N-M-I-V-T-V-K-F-Y-K-G-E-A-F-S-V-E-P-P-T-F-V-E-L-E-V-I-D-T-E-P-G-V-R-G-D-T-V-T-G-G-S-K-P-A-T-V-E-T-G-A-V-I-Q-V-P-L-F-I-N-V-G-D-K-I-K-I-D-T-R-T-G-E-Y-I-E-R-V"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-L-D-D-I-K-E-M-I-R-E-I-P-D-F-P-K-K-G-I-R-F-K-D-I-T-P-V-L-K-D-A-K-A-F-N-Y-S-I-E-M-L-A-K-A-L-E-G-R-K-F-D-L-I-A-A-P-E-A-R-G-F-L-F-G-A-P-L-A-F-R-L-G-V-G-F-V-P-V-R-K-P-G-K-L-P-A-E-T-L-S-Y-E-Y-E-L-E-Y-G-L-D-S-L-E-I-H-K-D-A-V-V-K-G-Q-R-V-V-I-V-D-D-L-L-A-T-G-G-T-V-Y-A-S-A-K-L-V-E-S-L-G-G-V-V-D-S-I-L-F-L-T-E-L-T-F-L-D-G-R-K-K-L-D-G-Y-D-I-I-S-L-I-K-F"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-E-Y-I-R-G-I-I-E-D-I-G-P-D-H-V-I-I-D-L-M-G-I-G-I-K-I-F-V-P-F-S-T-M-K-E-L-P-P-K-G-N-I-T-K-L-Y-T-Y-L-Y-V-R-E-D-G-F-Q-I-F-G-F-K-R-K-E-E-L-E-L-F-E-K-L-L-S-V-S-G-V-G-P-K-G-A-L-S-I-L-S-V-V-P-I-E-S-F-I-K-A-V-N-S-G-D-Y-K-I-L-T-A-A-P-G-I-G-K-K-T-A-E-R-I-I-L-E-L-K-D-K-V-P-K-E-V-V-V-P-K-E-D-S-L-L-N-E-A-L-E-A-L-L-A-L-G-Y-T-K-S-E-A-I-Y-A-L-S-D-V-N-C-E-S-V-E-Q-A-V-K-E-A-L-K-K-L-A-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-K-E-K-E-E-I-K-I-I-A-Q-N-R-K-A-F-H-D-Y-F-I-E-E-T-Y-E-A-G-I-E-L-V-G-T-E-V-K-S-V-R-Q-G-K-V-N-L-K-D-S-F-A-R-V-E-N-N-E-V-I-L-Y-N-M-H-I-S-P-Y-E-K-G-N-I-F-N-K-D-P-L-R-P-R-K-L-L-L-H-R-H-E-I-N-K-L-S-G-Y-V-S-R-K-G-Y-T-L-I-P-T-K-V-Y-L-K-R-G-L-V-K-V-E-L-A-V-A-K-G-K-K-L-F-D-K-R-E-D-I-A-R-R-D-A-K-R-E-L-E-K-Q-F-K-E-K-Q-L-G-I"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-N-V-L-I-D-N-R-Q-T-K-V-D-A-S-G-L-E-A-L-V-V-R-A-I-K-A-T-L-E-E-E-E-V-V-D-E-V-E-V-S-V-S-F-V-D-N-E-E-I-R-K-L-N-K-Y-Y-R-G-I-D-S-S-T-D-V-L-S-F-P-L-M-E-F-E-E-I-E-E-G-E-E-D-E-K-D-A-E-E-I-Y-P-I-G-D-I-V-I-S-L-E-K-A-K-E-Q-A-E-E-Y-G-H-S-F-E-R-E-V-A-Y-L-T-V-H-S-M-L-H-L-L-G-Y-D-H-E-T-E-E-E-R-K-L-M-R-E-K-E-E-K-V-M-E-R-L-G-L-R-R"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-V-K-L-N-S-I-E-E-V-D-L-L-A-N-T-K-S-A-K-K-R-I-A-I-I-K-K-R-T-L-R-N-K-M-I-K-S-R-V-K-T-F-I-R-R-F-N-E-S-L-A-T-K-D-I-E-A-I-K-E-R-L-R-L-A-V-K-E-L-D-K-A-V-S-K-G-V-L-H-K-N-T-A-A-R-K-K-S-K-L-Y-A-K-F-N-A-L-L-K-S-A-S-N-E"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-E-T-G-G-K-Q-Y-M-V-R-E-G-D-V-L-K-V-E-K-L-N-Y-P-E-G-E-V-I-A-L-D-K-V-L-A-V-S-F-E-D-G-N-V-E-F-G-K-P-Y-L-E-N-V-K-V-T-A-K-V-L-E-H-G-K-G-P-K-I-R-V-F-K-Y-K-P-K-K-N-Y-R-R-R-Q-G-H-R-Q-P-Y-T-K-I-Q-I-E-K-I-E-K"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-N-I-A-L-I-A-H-D-Q-K-K-E-L-M-V-N-F-A-I-A-Y-K-H-I-F-E-K-C-N-L-Y-A-T-G-H-T-G-Q-L-I-K-E-A-T-G-L-D-V-H-C-L-L-P-G-P-L-G-G-D-Q-Q-I-G-A-L-I-A-E-N-K-I-D-L-V-I-F-L-R-D-P-L-T-V-Q-P-H-E-P-D-I-L-A-L-L-R-V-C-D-V-H-S-I-P-V-A-T-N-I-A-T-A-E-V-L-L-K-G-M-E-M-G-L-L-D-W-R-Q-I"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-D-L-F-K-A-F-G-G-K-S-N-S-K-D-I-A-K-E-R-L-Q-L-L-L-V-H-D-R-I-D-T-S-P-R-F-L-E-M-I-K-E-D-I-L-N-V-I-S-N-Y-V-D-I-D-E-K-G-L-R-V-E-I-T-K-E-R-K-S-D-D-T-F-I-S-A-L-H-A-N-I-P-I-K-K-M-K-Q-V-I-R"} +{"text": "### FUNCTION Probable toxic component of a putative type VII toxin-antitoxin system, probably an RNase Probably neutralized by cognate antitoxin TTE0751 Neutralization may be due to AMPylation by TTE0751 ### SEQUENCE -M-K-T-P-R-P-Y-L-E-H-I-L-Q-E-C-E-F-L-I-E-R-V-K-G-I-S-F-E-D-F-V-K-D-P-V-L-T-R-A-F-V-R-S-L-E-I-I-G-E-A-V-K-N-L-P-K-E-F-R-E-K-H-S-K-V-P-W-K-E-I-A-G-M-R-D-K-L-I-H-E-Y-F-G-V-N-Y-R-I-I-W-E-T-I-L-K-E-I-P-E-L-E-K-Q-V-K-E-I-L-Q-K-E-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-D-K-T-F-H-L-E-V-L-T-P-Y-R-K-F-Y-E-G-D-V-E-E-I-I-V-T-T-T-T-G-Q-I-G-I-L-K-D-H-I-P-L-T-T-P-I-A-Q-A-G-T-L-Q-I-K-K-D-G-Q-W-K-E-A-F-I-S-G-G-F-M-E-V-R-R-D-G-V-T-I-L-S-S-A-A-E-W-P-E-E-I-D-I-A-R-A-Q-A-A-K-E-R-A-E-E-K-L-R-Q-K-K-S-K-Q-E-Y-I-A-A-E-A-A-L-K-R-A-L-M-R-L-K-I-A-S-K-Y-Q-E-M"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-E-Q-I-I-A-K-R-Y-A-S-A-L-F-D-V-A-K-K-E-D-R-V-K-E-Y-Y-E-E-L-K-K-A-V-E-I-L-Q-T-E-A-V-W-K-I-F-V-N-K-S-I-D-K-T-K-K-M-K-F-V-E-E-V-L-E-G-F-S-K-E-I-V-N-F-V-K-V-A-I-S-K-H-R-E-N-L-I-K-E-I-L-N-E-F-E-A-L-Y-K-A-Y-F-N-M-I-D-V-K-V-I-S-A-Y-P-L-K-E-E-V-L-N-L-V-R-E-K-L-E-K-K-Y-N-K-K-V-N-L-I-P-V-V-D-K-E-I-L-G-G-L-K-L-V-I-G-N-T-V-I-D-G-S-I-K-A-R-L-E-A-L-L-K-N-M-R-Q-A-V"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-E-G-K-A-L-E-L-F-N-L-S-T-F-V-F-T-I-I-N-L-L-V-L-Y-Y-I-L-K-R-L-L-F-K-P-V-T-K-F-L-E-D-R-E-N-K-I-K-S-A-L-E-D-A-D-K-Q-R-E-E-A-Y-S-L-K-A-Q-Y-E-E-K-L-Q-N-A-E-N-E-G-R-A-I-I-E-K-A-Q-K-E-A-E-E-R-A-S-E-I-I-K-S-A-N-K-E-A-E-S-I-I-E-K-A-K-E-E-A-V-L-E-K-I-K-A-M-H-E-L-R-A-E-M-S-H-L-I-I-E-A-A-S-K-V-L-E-K-K-L-P-V-E-D-E-D-L-I-K-E-V-I-E-E-A-G-S-W-N-K"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-K-I-K-T-A-E-F-V-G-S-A-F-N-E-S-Q-Y-P-K-D-K-I-P-Q-I-A-I-V-G-K-S-N-V-G-K-S-T-L-I-N-T-V-L-G-R-K-N-L-A-K-V-S-S-T-P-G-K-T-R-G-I-N-F-Y-L-V-N-R-A-F-Y-I-V-D-L-P-G-Y-G-Y-A-K-V-S-K-E-M-K-K-Q-W-A-Y-N-I-E-T-F-L-N-T-S-K-N-L-K-H-A-L-L-L-I-D-I-R-R-E-P-T-E-D-D-F-M-M-V-N-W-F-S-F-K-N-L-P-F-S-V-V-L-T-K-A-D-K-V-N-K-S-E-A-N-K-A-I-E-N-I-C-R-S-F-N-I-S-S-D-R-V-I-V-F-S-A-V-E-K-T-G-I-S-E-I-L-R-I-F-E-E-V-I-E-K"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-A-I-S-K-S-E-V-E-Y-I-A-K-L-A-R-L-K-F-T-E-E-E-I-E-A-M-A-Q-E-L-S-K-I-L-D-Y-V-N-K-L-N-E-L-D-T-E-N-V-E-P-T-A-H-I-V-P-I-H-N-V-F-R-E-D-E-V-K-P-S-M-P-R-E-K-V-L-M-N-A-P-F-T-E-Q-G-C-F-K-V-P-K-I-I-E"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-E-L-N-T-K-N-F-G-I-I-H-Y-N-E-E-D-V-I-Y-F-E-E-G-I-P-G-F-E-E-L-H-N-F-L-I-I-G-D-E-E-E-D-M-P-F-K-W-L-Q-S-I-D-N-P-D-I-A-F-V-V-I-D-P-R-V-F-K-P-D-Y-T-F-E-I-D-E-E-L-K-N-F-L-A-V-E-D-V-N-H-L-L-I-F-V-I-V-V-I-P-E-K-I-E-E-M-T-A-N-L-K-A-P-I-I-I-N-A-E-N-N-R-G-V-Q-I-I-L-D-N-D-K-Y-L-I-K-H-P-I-L-E-E-L-K-N-A-Y-S-H-A"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-E-V-L-E-G-L-Y-Y-S-K-D-H-E-W-V-K-V-E-G-D-K-V-Y-I-G-I-T-D-Y-A-Q-H-S-L-G-N-I-V-Y-V-E-L-P-E-V-G-S-E-L-S-A-G-D-V-L-G-V-V-E-S-V-K-A-A-S-D-V-Y-T-P-V-D-I-K-V-L-E-V-N-N-S-L-V-E-D-P-S-L-I-N-N-D-P-Y-G-S-W-M-V-I-A-E-L-K-D-K-S-Q-L-D-K-L-M-K-A-D-E-Y-R-K-F-L-E-E-E"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-P-G-I-H-P-T-Y-Y-H-D-A-V-V-K-C-A-C-G-N-T-F-I-T-G-S-T-K-K-E-I-R-V-E-I-C-S-K-C-H-P-F-F-T-G-Q-Q-K-I-V-D-T-G-G-R-V-E-R-F-R-K-R-F-N-L-E-E-K"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-V-T-Q-G-L-V-D-M-L-V-E-E-A-E-K-R-K-V-K-K-V-T-K-V-T-V-V-I-G-E-L-T-G-I-E-S-E-S-V-K-F-Y-F-D-I-L-T-E-N-T-V-A-E-G-A-E-L-V-F-K-I-V-R-A-Q-F-K-C-T-Q-C-G-N-V-F-E-R-S-N-F-T-F-K-C-P-V-C-G-G-Q-G-V-L-I-D-K-R-G-K-E-F-Y-I-E-S-I-E-V-E"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-K-V-L-E-D-L-Y-Y-S-K-D-H-V-W-V-K-V-E-G-D-K-A-Y-I-G-I-T-D-Y-A-Q-D-S-L-G-D-A-E-Y-I-E-L-P-E-V-G-T-E-F-T-A-G-D-V-L-G-V-I-E-S-A-K-A-A-S-D-V-Y-I-P-V-D-G-E-V-I-E-V-N-N-A-V-A-E-D-P-S-L-V-N-S-D-P-Y-G-S-W-L-V-A-V-R-L-K-D-K-A-Q-V-E-K-L-M-K-A-E-E-Y-K-K-F-L-E-T"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-Y-Y-S-T-S-V-A-K-L-I-E-E-L-S-K-L-P-G-I-G-P-K-T-A-Q-R-L-A-F-F-I-I-N-M-P-L-D-E-V-R-S-L-S-Q-A-I-I-E-A-K-E-K-L-R-Y-C-K-I-C-F-N-I-T-D-K-E-V-C-D-I-C-S-D-E-N-R-D-H-S-T-I-C-V-V-S-H-P-M-D-V-V-A-M-E-K-V-K-E-Y-K-G-V-Y-H-V-L-H-G-V-I-S-P-I-E-G-V-G-P-E-D-I-R-I-K-E-L-L-E-R-V-R-D-G-S-V-K-E-V-I-L-A-T-N-P-D-I-E-G-E-A-T-A-M-Y-I-A-K-L-L-K-P-F-G-V-K-V-T-R-I-A-H-G-I-P-V-G-G-D-L-E-Y-T-D-V-V-T-L-S-K-A-L-E-G-R-R-E-V"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-K-G-G-F-P-G-G-F-N-I-N-N-M-I-K-Q-A-Q-Q-M-Q-E-E-I-K-K-M-Q-E-E-L-M-Q-K-T-V-E-G-T-S-G-G-G-M-V-K-A-V-A-N-G-R-K-E-L-V-S-I-N-I-N-P-E-V-V-D-K-D-D-V-E-T-L-E-D-L-V-L-A-A-V-N-Q-A-L-R-N-A-E-E-M-I-A-S-E-M-A-K-I-T-G-G-F-N-I-P-G-L-F"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-Q-G-K-A-I-K-Y-G-D-N-I-D-T-D-V-I-I-P-A-R-F-L-N-T-S-D-P-K-E-L-A-E-H-C-M-E-D-L-D-R-E-F-K-N-K-V-K-E-G-D-I-L-V-V-G-E-N-F-G-C-G-S-S-R-E-H-A-P-L-A-I-K-A-S-G-I-S-C-I-I-A-K-S-F-A-R-I-F-Y-R-N-A-I-N-I-G-L-P-I-L-E-S-R-E-A-V-D-G-I-E-E-G-D-I-V-S-V-D-V-D-N-G-I-I-R-N-V-T-K-G-T-E-F-K-A-Q-P-F-P-E-F-I-K-E-I-I-K-Y-G-G-L-I-N-Y-V-R-E-K-V-R"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-V-L-K-T-V-G-V-A-G-T-L-E-S-S-D-A-M-I-T-V-E-P-A-N-Q-G-G-I-V-I-D-I-S-S-S-V-K-R-Q-F-G-R-Q-I-E-E-T-V-L-N-T-I-K-E-L-G-V-E-N-A-N-V-K-V-V-D-K-G-A-L-N-Y-A-L-I-A-R-T-K-A-A-V-Y-R-A-A-E-S-N-D-Y-K-F"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-I-G-I-G-N-D-I-I-E-I-E-R-I-E-K-A-I-S-K-E-G-F-K-N-K-I-Y-T-Q-K-E-L-E-N-I-Q-K-R-G-N-R-T-E-T-Y-A-G-I-F-S-A-K-E-A-I-S-K-A-I-G-T-G-V-R-E-F-S-L-T-D-L-E-I-L-N-D-D-L-G-K-P-Y-V-V-V-S-E-K-L-D-K-I-L-R-N-K-K-E-N-Y-Q-I-E-I-S-I-S-H-S-R-K-Y-A-T-A-M-A-I-I-L"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-I-P-R-N-K-R-V-E-I-A-L-T-Y-I-Y-G-I-G-K-P-T-S-Q-K-I-L-K-E-A-G-I-N-F-D-T-R-V-K-D-L-T-E-E-E-I-N-K-I-R-E-I-I-K-D-I-K-V-E-G-D-L-R-K-E-V-R-L-S-V-K-R-L-M-D-I-K-C-Y-R-G-L-R-H-K-M-N-L-P-V-R-G-Q-S-S-K-T-N-A-R-T-V-K-G-P-K-K-P-I-R-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-K-T-V-A-K-I-K-K-K-S-K-N-I-P-N-G-V-A-H-I-H-S-T-F-N-N-T-I-V-A-I-T-D-V-D-G-K-V-V-S-W-K-S-G-G-T-S-G-F-K-G-T-K-K-G-T-P-F-A-A-Q-I-A-A-E-Q-A-A-Q-I-A-M-E-N-G-M-R-K-V-E-V-K-V-K-G-P-G-S-G-R-E-A-C-I-R-S-L-Q-A-A-G-L-E-V-T-K-I-T-D-V-T-P-V-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-R-N-R-Q-P-V-L-K-K-C-R-A-L-G-I-D-P-V-I-L-G-V-K-K-S-S-N-R-Q-I-R-P-N-A-N-K-K-P-T-E-Y-A-T-Q-L-R-E-K-Q-K-A-K-F-I-Y-N-V-M-E-K-Q-F-R-K-I-Y-E-E-A-A-R-K-L-G-V-T-G-L-T-L-I-E-Y-L-E-R-R-L-E-N-V-V-Y-R-L-G-F-A-K-T-R-R-Q-A-R-Q-I-V-S-H-G-H-I-A-V-N-G-R-R-V-N-I-A-S-F-R-V-K-V-G-D-I-V-S-V-I-E-N-S-K-N-V-E-L-I-K-L-A-V-E-D-A-T-P-P-A-W-L-E-L-D-R-A-A-F-S-G-K-V-L-Q-N-P-T-K-D-D-L-D-F-D-L-N-E-S-L-I-V-E-F-Y-S-R"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-K-R-N-I-N-L-F-K-C-G-G-D-K-M-Y-V-V-V-V-Y-D-I-S-L-D-E-K-G-S-R-N-W-R-K-I-F-G-I-C-K-R-Y-L-H-H-I-Q-N-S-V-F-E-G-E-L-S-E-V-D-I-Q-R-L-K-Y-E-V-S-K-Y-I-R-D-D-L-D-S-F-I-I-F-K-S-R-N-E-R-W-M-E-K-E-M-L-G-L-Q-E-D-K-T-D-N-F-L"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-K-I-A-I-Y-G-G-S-F-N-P-M-H-I-G-H-E-K-I-V-D-Y-V-L-K-N-L-D-M-D-K-I-I-I-I-P-V-G-I-P-S-H-R-E-N-N-L-E-Q-S-D-T-R-L-K-I-C-K-E-I-F-K-N-N-K-K-V-E-V-S-D-I-E-I-K-A-E-G-K-S-Y-T-Y-D-T-L-L-K-L-I-E-I-Y-G-K-D-N-E-F-F-E-I-I-G-E-D-S-L-K-N-L-K-T-W-R-N-Y-K-E-L-L-N-L-C-K-F-I-V-F-R-R-K-D-D-K-N-I-E-I-D-N-E-F-L-N-N-K-N-I-I-I-L-E-N-E-Y-Y-N-I-S-S-T-E-I-R-N-K-V-K-N-K-E-D-I-S-G-L-V-N-K-K-V-K-K-L-I-E-K-E-Y-I-D"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-K-T-G-G-K-Q-Y-K-V-T-E-G-D-V-L-K-V-E-K-L-N-A-E-V-N-T-T-V-E-L-T-E-V-L-L-V-A-G-G-D-N-A-V-K-V-G-K-P-L-V-E-G-A-K-V-V-V-E-V-L-S-Q-G-K-G-P-K-V-I-N-F-K-Y-K-P-K-K-A-S-H-R-K-R-G-H-R-Q-L-F-T-E-V-K-V-T-S-I-I-A"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-F-E-Y-L-Y-G-T-V-E-Y-K-K-M-D-Y-I-A-I-D-I-N-G-V-G-Y-R-V-Y-F-P-L-R-E-Y-E-K-I-E-V-G-N-K-Y-K-L-Y-I-Y-N-H-I-K-E-D-T-Y-K-L-I-G-F-L-D-E-R-D-R-K-I-F-E-L-L-L-K-I-N-G-I-G-S-S-L-A-L-A-V-L-S-N-F-S-Y-N-K-I-I-E-I-I-S-K-N-D-Y-T-T-L-R-Q-V-P-K-L-G-E-K-K-A-Q-I-I-I-L-D-L-K-G-K-L-K-N-L-T-Y-T-E-E-E-T-V-S-M-D-M-L-E-D-L-V-L-A-L-E-G-L-G-Y-N-K-K-E-I-D-K-T-L-E-K-I-D-L-N-K-F-S-S-L-E-D-A-I-K-G-I-L-K-N-M-R-I-G-D"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-K-V-Q-V-K-V-I-R-E-E-G-V-E-L-P-K-Y-E-T-E-G-S-A-G-M-D-V-R-A-N-I-K-E-S-I-T-L-K-S-L-E-R-I-L-V-P-T-G-L-K-V-A-I-P-E-G-Y-E-I-Q-V-R-P-R-S-G-L-A-I-K-H-G-I-T-M-L-N-T-P-G-T-V-D-S-D-Y-R-G-E-L-K-V-I-V-V-N-L-S-N-E-A-Y-T-I-E-P-N-E-R-I-G-Q-F-V-L-N-K-I-E-Q-I-E-F-V-E-V-E-E-L-D-S-T-E-R-G-E-S-G-F-G-H-T-G-K"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-V-L-G-G-L-M-K-L-F-D-E-F-K-A-F-V-M-R-G-N-V-V-D-L-A-V-G-V-I-I-G-A-A-F-G-K-I-V-T-S-L-V-N-D-I-F-M-P-I-I-G-M-I-I-G-N-I-D-F-S-S-L-V-I-K-L-G-E-P-V-E-G-A-E-Q-A-A-I-R-Y-G-M-F-I-Q-E-I-V-N-F-L-I-I-A-L-C-V-F-V-A-I-K-L-I-N-K-L-Q-K-K-K-E-E-A-S-A-P-A-P-G-P-T-K-E-E-V-L-L-T-E-I-R-D-A-L-N-K-I-A-E-K"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-K-R-Y-I-A-L-D-I-G-D-V-R-I-G-V-A-R-S-D-I-M-G-I-I-A-S-P-L-E-T-I-N-R-K-K-V-K-S-V-K-R-I-A-E-I-C-K-E-N-D-T-N-L-V-V-V-G-I-P-K-S-L-D-G-E-E-K-R-Q-A-E-K-V-R-E-Y-I-E-K-L-K-K-E-I-E-N-L-E-I-I-E-V-D-E-R-F-S-T-V-I-A-D-N-I-L-K-E-L-N-K-N-G-A-I-E-K-R-K-V-V-D-K-V-A-A-S-I-I-L-Q-T-Y-L-D-M-K-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-I-I-A-N-N-K-K-A-F-F-D-Y-F-I-E-E-K-Y-E-A-G-I-E-L-K-G-S-E-V-K-S-I-K-A-G-K-V-S-I-K-E-A-F-V-R-I-I-N-D-E-I-F-I-M-G-M-S-V-V-P-W-E-F-G-S-V-Y-N-P-E-E-R-R-V-R-K-L-L-L-H-R-K-E-I-K-K-I-H-E-K-V-K-I-K-G-Y-T-I-V-P-L-D-V-H-L-S-K-G-Y-V-K-M-Q-I-A-I-A-K-G-K-K-T-Y-D-K-R-E-S-I-A-K-K-D-Q-E-R-N-L-K-R-E-F-K-N-N-N-R"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-M-Q-L-M-K-I-T-I-K-G-N-K-L-I-L-D-N-D-K-I-I-Y-L-T-K-E-M-F-S-K-F-D-L-K-D-K-T-S-L-D-D-E-T-F-Y-S-L-I-Y-F-R-I-K-L-S-A-Y-T-M-L-A-K-R-D-Y-F-K-K-E-L-K-N-K-L-I-E-K-I-G-F-A-D-I-V-K-D-V-V-E-D-F-E-E-K-G-Y-L-D-D-Y-E-K-A-K-S-Y-A-A-Q-H-S-N-Y-G-T-K-K-L-S-F-I-L-Y-Q-M-G-V-D-K-E-I-V-S-E-I-L-E-D-E-K-D-N-Q-I-E-K-I-K-Q-L-W-I-K-L-G-N-K-E-Y-K-K-K-I-E-S-I-L-R-K-G-F-L-Y-G-D-I-K-K-A-I-S-S-L-E-E-E-E-E"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-G-I-H-P-E-F-D-L-V-V-F-E-D-M-A-G-N-Q-F-L-T-R-S-T-K-I-P-K-E-T-T-T-F-E-G-K-E-Y-P-V-I-K-V-A-V-S-S-K-S-H-P-F-Y-T-G-E-Q-R-F-V-D-T-A-G-R-V-D-K-F-N-K-K-F-N-L-G-K-K"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-N-I-N-I-I-C-I-G-K-I-K-D-K-Y-I-N-D-G-I-A-E-F-S-K-R-M-T-S-F-V-S-L-N-I-I-E-L-K-E-Y-N-K-E-D-N-I-N-I-S-I-E-K-E-S-L-E-I-L-K-Q-I-S-K-S-N-S-Y-N-I-L-L-D-L-E-G-K-E-I-N-S-E-N-M-S-K-Y-I-E-N-L-K-N-I-G-I-S-S-I-N-F-I-I-G-G-S-N-G-V-S-K-N-V-K-N-S-V-D-M-K-L-K-F-S-H-F-T-F-P-H-Q-L-M-R-L-I-L-L-E-Q-V-Y-R-W-F-A-I-S-N-N-I-K-Y-H-K"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-K-E-K-L-I-E-L-V-E-K-E-Y-L-R-S-D-I-P-Q-F-K-A-G-D-T-I-G-V-Y-Y-K-V-K-E-G-N-K-E-R-V-Q-L-F-E-G-V-V-I-R-V-N-G-G-G-V-A-K-T-F-T-V-R-K-V-T-A-G-I-G-V-E-R-I-I-P-V-N-S-P-N-I-D-R-I-E-V-L-K-V-G-R-V-R-R-S-K-L-Y-Y-L-R-G-L-S-A-K-K-A-R-I-K-E-I-V-K"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-E-V-K-M-K-I-L-L-D-E-D-G-I-R-R-S-I-T-R-I-S-Y-E-I-I-E-R-N-K-T-V-D-N-I-V-L-V-G-I-K-S-R-G-D-I-L-A-E-R-I-K-Q-K-L-L-E-V-E-N-I-D-A-P-L-E-T-I-D-I-T-Y-Y-R-D-D-I-D-R-K-N-F-D-L-D-I-K-D-T-E-F-K-T-N-L-T-G-K-V-V-V-I-V-D-D-V-L-Y-T-G-R-T-I-R-A-G-L-D-A-I-L-S-K-S-R-P-A-K-I-Q-L-A-C-L-I-D-R-G-H-R-E-L-P-I-R-A-D-F-I-G-K-N-I-P-T-S-H-S-E-N-I-E-V-Y-L-K-E-L-D-G-K-E-E-V-V-I-L"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-P-T-K-S-L-E-R-L-I-L-E-F-N-K-L-P-G-V-G-Q-K-S-A-T-R-Y-A-F-H-I-L-N-Q-S-E-E-D-V-K-N-F-A-E-A-L-L-A-V-K-E-N-V-K-K-C-H-V-C-G-N-Y-C-E-S-D-T-C-N-I-C-S-D-N-A-R-D-H-R-I-I-C-V-V-E-E-S-K-D-I-M-I-L-E-K-T-T-K-F-R-G-V-Y-H-V-L-N-G-R-L-D-P-L-N-G-I-T-P-N-E-L-N-I-K-S-L-L-E-R-I-A-K-D-D-I-E-E-I-I-L-A-T-N-P-N-I-E-G-E-T-T-A-M-Y-L-A-K-L-M-K-N-F-G-I-K-I-T-K-L-A-S-G-I-P-M-G-G-N-L-E-F-S-D-T-A-T-I-S-R-A-L-D-D-R-I-E-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-P-I-I-S-I-D-Y-T-F-F-W-Q-I-I-N-F-F-L-L-L-F-I-V-K-K-Y-F-K-E-P-I-S-K-I-I-N-E-R-K-Q-K-I-E-A-E-L-V-E-A-T-K-N-K-K-E-A-E-Q-L-L-K-D-A-E-A-Q-I-N-A-S-R-K-E-A-T-E-I-V-K-A-A-Q-R-K-A-E-E-E-A-H-N-L-I-R-E-A-R-E-N-R-E-N-I-L-K-T-T-E-L-E-I-T-K-I-K-N-D-A-K-E-E-L-G-R-E-V-K-N-L-A-A-E-L-A-E-K-I-I-K-E-K-V-D-D-A-Q-E-I-S-L-I-D-K-F-I-A-E-V-G-E-D-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-I-K-S-Q-V-G-R-R-Y-S-K-A-I-F-E-I-A-E-E-K-K-Q-V-K-E-I-Y-E-M-L-N-S-A-M-V-L-Y-R-T-D-K-E-F-K-H-F-I-L-N-P-L-I-D-N-E-Q-K-K-S-V-L-N-E-I-F-G-K-D-N-S-E-N-L-N-I-L-L-Y-I-L-D-K-G-R-M-N-C-I-K-Y-I-V-A-E-Y-L-K-I-Y-Y-R-K-N-R-I-L-D-V-K-A-T-F-T-K-E-L-T-D-E-Q-K-K-K-L-I-D-K-L-S-Q-K-T-G-K-E-I-N-L-E-I-K-I-D-K-D-I-L-G-G-G-I-I-K-I-G-D-K-I-I-D-G-S-I-R-R-E-L-D-N-W-R-K-S"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-R-V-K-T-G-I-I-R-R-K-R-H-K-R-V-L-K-A-A-K-G-F-R-G-A-S-G-D-A-F-K-Q-A-K-Q-A-T-R-R-A-M-A-F-A-T-R-D-R-K-V-N-K-R-R-M-R-Q-L-W-I-T-R-I-N-S-A-A-R-M-N-G-V-S-Y-S-V-L-M-N-G-L-K-K-A-G-I-L-L-D-R-K-V-L-A-D-I-A-L-N-N-A-T-E-F-T-K-L-V-E-A-A-K-S-A-L"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-L-L-I-A-G-K-V-L-G-S-H-N-L-K-G-E-V-K-V-I-S-D-L-D-N-I-E-V-L-V-G-N-K-V-I-L-E-L-A-D-S-Q-Q-K-L-L-T-I-K-K-I-E-H-L-V-A-N-K-W-I-F-S-F-E-E-I-K-N-K-Q-D-T-I-E-I-R-N-A-N-I-K-V-R-R-D-I-V-G-I-G-E-D-E-Y-L-V-S-D-M-I-G-F-K-V-Y-D-V-K-G-D-E-Y-L-G-E-I-T-E-I-M-D-T-A-A-H-D-I-Y-V-I-E-S-E-E-F-E-T-M-I-P-D-V-D-V-F-I-K-N-I-D-F-E-N-R-K-M-L-V-D-T-I-E-G-M-K-E-S-K-V-K-K"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-G-F-F-S-N-F-F-K-K-E-N-S-K-D-D-A-K-N-R-L-K-L-V-L-I-Q-D-R-A-M-L-P-S-G-V-L-E-N-M-K-D-D-I-L-K-V-L-S-K-Y-V-E-I-E-K-S-K-L-N-I-E-M-C-P-Y-E-D-D-P-R-K-I-A-L-V-A-N-I-P-I-L-K-S-S-T-R-E-V-T-K-T-T-K-Q-Q-K-R-K"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-L-D-K-V-K-E-I-I-V-E-Q-L-G-V-D-A-D-Q-I-K-P-E-S-N-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-I-M-S-F-E-E-E-F-G-V-E-I-P-D-T-E-A-E-K-I-K-T-V-Q-D-V-I-N-Y-I-E-A-N-K-K"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-K-D-K-E-I-K-E-E-V-L-K-E-E-I-N-K-E-V-N-E-K-K-K-C-E-C-E-E-G-K-E-E-A-H-E-H-K-N-D-E-H-A-C-C-G-K-H-N-H-K-E-E-I-E-K-L-K-A-E-I-E-E-W-K-N-S-F-L-R-K-Q-A-D-F-Q-N-F-T-K-R-K-E-K-E-V-D-E-L-K-K-F-A-S-E-K-I-I-T-Q-F-L-G-S-L-D-N-F-E-R-A-I-E-S-S-S-E-S-K-D-F-D-S-L-L-Q-G-V-E-M-I-V-R-N-L-K-D-I-M-S-S-E-D-V-E-E-I-P-T-E-G-A-F-N-P-E-Y-H-H-A-V-G-V-E-T-S-E-D-K-K-E-D-E-I-V-K-V-L-Q-K-G-Y-M-M-K-G-K-V-I-R-P-A-M-V-I-V-C-K-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-N-V-K-I-K-K-V-D-G-D-K-F-D-R-L-R-A-Y-V-D-V-T-L-D-D-C-L-V-I-H-G-L-K-L-M-Q-G-E-Q-G-M-F-V-A-M-P-S-R-K-M-R-N-E-E-F-K-D-I-V-H-P-I-C-P-E-L-R-N-D-I-T-K-V-V-Q-E-K-Y-F-A-L-D-Q-E-Q-E-A-V-I"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-T-L-K-K-N-G-E-F-Q-N-I-Y-N-L-G-N-K-Y-F-G-N-Y-S-L-I-F-F-N-K-N-K-L-E-Y-S-R-F-G-F-I-A-S-K-K-V-G-K-A-F-C-R-N-R-I-K-R-L-F-R-E-Y-I-R-L-N-I-N-K-I-N-D-N-Y-D-I-I-I-V-A-K-K-K-F-G-E-N-I-E-D-L-K-Y-K-D-I-E-K-D-L-N-R-V-F-K-N-S-K-I-I"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-E-V-I-Q-I-I-K-L-Q-L-P-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-F-N-A-K-T-Q-D-K-A-G-W-I-I-P-V-E-I-S-V-Y-S-D-R-S-F-T-F-I-L-K-T-P-P-A-S-D-L-L-K-K-A-A-G-I-T-S-G-A-K-N-S-K-K-E-V-A-G-K-I-T-T-A-K-L-K-E-L-A-E-T-K-M-P-D-L-N-A-S-S-V-E-T-A-M-K-I-I-A-G-S-A-R-S-M-G-I-K-I-E-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-T-Q-V-K-K-E-L-V-A-E-L-V-E-K-I-K-K-A-Q-S-V-V-F-V-D-Y-Q-G-I-K-V-N-E-E-T-L-L-R-K-Q-M-R-E-N-G-A-E-Y-L-V-A-K-N-R-L-F-K-I-A-L-K-E-S-G-V-E-D-S-F-D-E-I-L-E-G-S-T-A-F-A-F-G-Y-N-D-P-V-A-P-A-K-A-V-F-D-L-A-K-A-K-A-K-A-K-L-D-V-F-K-I-K-G-G-Y-L-T-G-K-K-V-S-V-K-E-V-E-E-L-A-K-L-P-S-R-E-Q-L-L-S-M-L-L-N-S-M-L-G-P-I-R-K-L-A-Y-A-T-V-A-I-A-D-K-K-E-G-S-A-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-F-N-K-E-Q-F-I-A-D-L-E-A-M-T-V-L-E-L-K-E-L-V-S-A-L-E-E-H-F-G-V-T-A-A-A-P-V-A-V-A-A-A-G-G-A-T-E-A-A-E-E-K-T-E-F-D-V-V-L-K-S-A-G-G-N-K-I-A-V-I-K-E-V-R-A-I-T-G-L-G-L-K-E-A-K-D-L-V-D-N-G-G-V-I-K-E-A-A-P-K-D-E-A-N-A-I-K-E-K-L-T-A-A-G-A-E-V-E-V-K"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-S-L-G-A-L-Y-V-V-S-G-P-S-G-A-G-K-S-T-V-C-K-L-V-R-E-R-L-G-I-N-L-S-I-S-A-T-S-R-K-P-R-N-G-E-Q-E-G-V-D-Y-F-F-I-T-A-E-E-F-E-R-K-I-K-N-D-D-F-L-E-Y-A-N-V-H-G-N-Y-Y-G-T-L-K-S-E-V-E-E-R-L-K-R-G-E-K-V-L-L-E-I-D-V-Q-G-G-V-Q-V-K-N-K-F-P-E-A-N-L-I-F-F-K-T-A-N-K-E-E-L-E-K-R-L-R-G-R-N-T-D-S-E-E-V-I-Q-A-R-L-K-N-S-L-K-E-L-E-Y-E-S-K-Y-D-R-V-I-I-N-N-E-I-E-Q-A-C-N-D-L-I-S-I-I-E-N-G-V-K"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-E-E-N-N-Q-I-V-E-K-I-T-R-I-V-N-P-F-I-E-E-M-N-L-S-L-V-D-V-E-Y-V-Q-D-G-G-Y-W-Y-V-R-I-F-I-E-N-L-N-G-D-L-N-I-E-D-C-S-K-L-S-S-K-I-E-D-K-V-E-E-L-I-E-H-K-F-F-L-E-V-S-S-P-G-L-E-R-P-L-K-K-L-E-D-Y-T-R-F-I-G-E-K-I-T-L-H-L-K-H-K-L-D-D-K-K-Q-F-K-T-I-I-K-E-V-N-G-D-N-I-I-F-L-M-D-K-K-E-V-E-I-K-F-N-E-I-R-K-A-N-I-L-F-E-F-N-D-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-K-Q-R-L-E-G-I-G-K-E-I-M-R-V-I-S-K-V-L-L-E-E-V-K-N-P-K-I-K-G-L-V-S-V-T-E-V-D-V-T-E-D-L-K-F-A-D-T-Y-F-S-I-L-P-P-L-K-S-D-E-K-K-Y-D-H-E-E-I-L-E-A-L-N-E-I-K-G-F-L-R-K-R-V-A-E-E-V-D-I-R-Y-T-P-E-I-R-V-K-L-D-N-S-M-E-N-A-I-K-I-T-K-L-L-N-D-L-K-V"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-K-I-K-K-A-D-F-V-K-S-A-V-Y-E-K-D-Y-P-E-Q-L-D-K-M-E-F-A-F-V-G-R-S-N-V-G-K-S-S-L-I-N-S-L-T-S-R-L-K-L-A-R-T-S-K-T-P-G-R-T-Q-L-I-N-Y-F-L-I-N-D-E-F-Y-I-V-D-L-P-G-Y-G-F-A-K-V-P-K-E-M-K-K-Q-W-G-Q-T-M-E-R-Y-I-A-S-K-R-K-K-L-V-F-V-L-L-D-I-R-R-V-P-S-D-E-D-I-E-M-L-E-W-L-E-Y-N-E-M-D-Y-K-I-I-F-T-K-I-D-K-L-S-N-N-E-R-A-K-Q-L-K-A-I-K-T-R-L-V-F-D-N-E-D-V-F-F-H-S-S-L-T-N-K-G-R-D-E-I-L-N-F-M-E-E-K-L-N-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-R-T-K-A-E-I-I-K-E-F-G-K-S-E-A-D-T-G-S-T-E-V-Q-I-A-L-L-T-E-K-I-N-H-L-T-E-H-L-R-V-H-K-K-D-F-H-S-R-L-G-L-L-K-M-V-G-Q-R-K-R-L-L-A-Y-L-T-K-K-D-L-E-G-Y-R-A-L-I-A-K-L-G-I-R-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-S-K-S-A-K-K-R-I-L-V-A-E-R-N-R-V-R-N-Q-A-V-K-T-R-V-K-T-M-A-K-K-V-L-S-T-I-E-V-K-D-V-E-A-A-K-V-A-L-S-V-A-Y-K-E-F-D-K-A-V-S-K-G-I-L-K-K-N-T-A-S-R-K-K-A-R-L-A-A-K-V-N-S-L-V-S-S-L"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-K-I-Q-V-I-L-L-E-D-V-A-G-Q-G-R-K-G-E-I-V-T-V-S-D-G-Y-A-H-N-F-L-L-K-G-K-K-G-V-L-A-T-P-E-E-L-Q-K-I-E-N-R-K-K-K-E-A-K-K-Q-E-E-E-R-N-K-S-L-E-L-K-K-L-L-E-S-K-V-L-D-I-P-V-K-A-G-E-N-G-K-L-F-G-A-I-T-S-K-E-I-A-S-Q-I-K-E-E-L-G-L-D-I-D-K-K-K-I-E-A-N-I-K-N-L-G-P-D-E-V-H-I-K-L-F-T-D-V-K-A-V-I-K-V-N-V-I-A-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-S-L-D-N-L-V-A-E-I-L-Q-Q-A-E-K-E-A-N-R-I-L-V-K-V-K-A-E-N-L-E-F-T-E-N-E-N-K-K-I-Q-K-E-I-E-N-I-Q-W-K-T-N-E-E-A-I-S-L-K-E-R-I-I-S-N-A-N-L-K-S-R-D-M-V-L-Q-A-K-E-E-L-V-D-K-V-L-K-M-T-L-E-R-L-K-N-L-D-S-D-S-Y-L-D-F-V-E-N-A-L-K-T-L-N-I-S-K-N-A-E-I-I-L-T-K-K-M-K-D-V-L-G-K-E-I-F-G-Y-K-V-S-D-D-I-V-E-S-G-C-N-I-K-D-G-N-V-I-Y-N-N-E-F-S-S-L-L-E-F-N-K-E-D-L-E-R-E-I-L-K-K-I-F-G"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-K-L-M-Y-K-I-A-V-I-G-D-K-D-S-V-L-A-F-K-I-L-G-V-D-V-F-I-T-L-D-A-Q-E-A-R-K-T-I-D-R-I-A-K-E-N-Y-G-I-I-F-V-T-E-Q-L-A-K-D-I-P-E-T-I-K-R-Y-N-S-E-I-I-P-A-V-I-L-I-P-S-N-K-G-S-L-N-I-G-L-T-N-I-D-K-N-V-E-K-A-I-G-S-K-I-M"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-K-Y-E-I-M-Y-I-I-N-P-T-V-L-E-E-G-R-E-E-L-V-N-Q-V-N-A-L-L-T-S-N-G-A-T-I-A-K-T-E-K-W-G-E-R-K-L-A-Y-P-I-D-K-K-K-S-G-F-Y-V-L-T-T-F-E-I-D-G-T-K-L-A-E-V-E-S-K-L-N-I-M-E-S-V-M-R-Y-I-V-V-K-Q-D"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-E-F-R-R-R-R-A-K-L-R-V-K-A-E-E-I-D-Y-K-N-V-E-L-L-K-R-F-V-S-D-K-G-K-I-N-P-S-R-L-T-G-A-N-A-K-L-Q-R-K-I-A-K-A-V-K-R-A-R-N-I-A-L-I-P-Y-T-R-T-E-K"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-S-N-K-L-R-I-Y-L-K-A-Y-D-H-T-L-L-D-E-S-A-K-R-I-A-E-S-A-K-K-S-G-A-I-V-A-G-P-M-P-L-P-T-K-I-R-K-Y-T-V-L-R-S-V-H-V-N-K-D-S-R-E-Q-F-E-M-R-V-H-R-R-M-I-E-L-V-N-S-T-D-K-A-I-S-S-L-T-S-V-H-L-P-A-G-V-G-I-E-I-K-Q-V"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-V-Y-D-I-I-K-K-P-V-V-T-E-K-T-E-L-L-R-K-E-Y-N-K-Y-T-F-E-V-H-P-K-A-N-K-I-E-I-K-K-A-V-E-A-I-F-N-V-K-V-E-D-V-A-T-I-N-K-K-P-I-T-K-R-H-G-M-R-L-Y-K-T-Q-A-K-K-K-A-I-V-K-L-A-K-E-N-T-I-T-Y-S-K-E-V"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-C-D-H-H-L-M-A-K-V-E-E-A-V-A-S-G-N-N-K-A-V-I-K-T-W-S-R-R-S-T-I-F-P-N-F-I-G-L-T-F-G-V-Y-N-G-K-K-H-I-P-V-H-V-T-E-Q-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-H-G-H-G-V-D-K-K-K-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-I-T-R-F-V-R-L-S-P-R-K-A-R-L-V-A-D-L-V-R-G-K-S-A-L-E-A-L-D-I-L-E-F-T-N-K-K-A-A-R-V-I-K-K-T-L-S-S-A-I-A-N-A-T-N-N-F-K-M-D-E-D-K-L-V-V-S-T-I-M-V-N-Q-G-P-V-L-K-R-V-M-P-R-A-M-G-R-A-D-I-I-R-K-P-T-A-H-I-T-V-A-V-S-D-E-Q"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-H-R-K-M-F-R-G-R-M-K-G-A-A-H-K-G-N-F-V-A-F-G-D-Y-G-L-Q-A-L-E-P-S-W-I-T-N-R-Q-I-E-S-C-R-V-A-I-N-R-T-F-K-R-E-G-K-T-Y-I-R-I-F-P-D-K-P-I-T-A-R-P-A-G-V-R-M-G-K-G-K-G-N-V-E-G-W-V-S-V-V-R-P-G-R-I-L-F-E-V-S-G-V-T-E-E-K-A-A-A-A-L-R-K-A-A-M-K-L-P-I-R-C-K-V-V-K-R-E-E-K-E-N-G-G-E-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-R-N-E-R-K-V-R-E-G-I-V-V-S-D-K-M-Q-K-T-I-V-V-A-I-E-T-M-I-L-H-P-I-Y-K-K-R-V-K-R-T-T-K-F-K-A-H-D-E-E-N-V-A-Q-V-G-D-K-V-K-I-M-E-T-R-R-L-S-K-D-K-N-W-R-L-V-E-I-I-E-K-A-R"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-V-Q-Q-Q-T-I-L-N-V-A-D-N-S-G-A-K-K-L-M-V-I-R-V-L-G-G-S-R-K-R-F-G-K-I-G-D-I-V-V-A-S-V-K-E-A-I-P-G-G-N-V-K-K-G-D-I-V-K-A-V-I-V-R-T-R-K-E-T-R-R-D-D-G-S-Y-I-K-F-D-D-N-A-G-V-V-I-N-N-N-N-E-P-R-A-T-R-I-F-G-P-V-A-R-E-L-R-A-R-N-F-M-K-I-L-S-L-A-I-E-V-I"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-K-P-K-I-K-F-V-P-D-S-L-H-V-K-T-G-D-I-V-Y-V-I-S-G-K-D-K-K-M-T-G-K-V-L-K-V-F-P-K-K-G-K-I-I-V-E-G-I-N-I-V-T-K-H-L-K-P-S-Q-V-N-P-Q-G-G-V-V-Q-K-E-A-A-I-F-S-S-K-V-M-L-F-D-E-K-T-K-S-P-T-R-V-G-Y-E-V-R-D-G-K-K-V-R-I-S-K-K-S-G-E-I-I"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-D-K-Y-T-S-R-Y-H-K-F-Y-D-E-V-V-V-P-K-L-M-K-E-L-E-I-K-N-I-M-E-C-P-K-L-E-K-I-I-V-N-M-G-V-G-E-A-T-Q-N-S-K-L-I-D-A-A-M-A-D-L-T-I-I-T-G-Q-K-P-L-L-R-K-A-K-K-S-E-A-G-F-K-L-R-E-G-M-P-I-G-A-K-V-T-L-R-K-E-R-M-Y-D-F-L-D-R-L-V-N-V-V-L-P-R-V-R-D-F-E-G-V-P-S-N-S-F-D-G-R-G-N-Y-S-V-G-L-R-D-Q-L-V-F-P-E-I-D-F-D-K-V-E-K-L-L-G-M-S-I-T-M-V-S-S-A-K-T-D-E-E-G-R-A-L-L-K-A-F-G-M-P-F-K-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-R-D-V-K-R-A-K-L-V-D-K-Y-A-E-K-R-A-E-L-K-K-R-I-A-A-G-D-M-E-A-M-F-E-L-N-K-L-P-K-D-S-S-A-V-R-K-R-N-R-C-Q-L-D-G-R-P-R-G-Y-M-R-E-F-G-I-S-R-V-K-F-R-Q-L-A-G-A-G-V-I-P-G-V-K-K-S-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-Y-L-T-D-P-I-A-D-M-L-T-R-V-R-N-A-N-A-V-M-H-E-K-V-D-I-P-H-S-K-M-K-E-R-I-A-E-I-L-K-E-Q-G-Y-I-S-N-F-K-I-V-T-D-E-G-N-K-K-N-I-R-V-Y-L-K-Y-A-G-K-E-R-V-I-K-G-L-K-R-I-S-K-P-G-R-R-V-Y-S-S-V-D-D-M-P-R-V-L-S-G-L-G-I-A-I-V-S-T-S-K-G-I-V-T-D-K-V-A-R-A-E-K-V-G-G-E-V-L-A-F-V-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-K-P-I-A-V-P-S-G-V-D-F-S-V-K-D-N-V-V-T-V-K-G-P-K-G-T-L-T-K-E-F-N-N-N-I-T-I-K-L-E-D-G-H-I-T-V-E-R-P-N-D-E-P-F-M-R-A-I-H-G-T-T-R-A-L-I-N-N-M-V-K-G-V-H-E-G-Y-R-K-T-L-T-L-V-G-V-G-Y-R-A-A-T-K-G-K-G-L-E-I-S-L-G-Y-S-H-P-V-I-I-D-E-I-P-G-I-T-F-S-V-E-K-N-T-T-I-H-I-D-G-V-E-K-E-L-V-G-Q-V-A-A-N-I-R-A-K-R-P-P-E-P-Y-K-G-K-G-V-K-Y-A-D-E-H-I-R-R-K-E-G-K-K-S"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-F-K-K-V-D-R-K-A-S-R-Q-K-K-Q-M-S-I-R-N-K-I-S-G-T-P-E-R-P-R-L-S-V-F-R-S-N-T-N-I-F-A-Q-L-I-D-D-V-N-G-V-T-L-V-S-A-S-T-I-D-K-A-L-K-G-S-I-A-N-G-G-N-I-E-A-A-K-A-V-G-K-A-I-A-E-R-A-K-E-K-G-I-D-A-I-V-F-D-R-S-G-Y-K-Y-T-G-R-V-A-A-L-A-D-A-A-R-E-A-G-L-S-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-L-N-R-E-D-N-Q-Y-Q-E-K-L-L-K-I-S-R-V-S-K-T-T-K-G-G-R-T-I-S-F-S-V-L-A-A-V-G-D-G-E-G-K-I-G-L-G-L-G-K-A-N-G-V-P-D-A-I-R-K-A-I-A-A-A-K-K-N-I-V-K-I-S-L-K-N-N-T-I-P-H-E-I-A-G-K-W-G-A-T-T-L-W-M-A-P-A-Y-E-G-T-G-V-I-A-G-S-A-S-R-E-I-L-E-L-V-G-V-H-D-I-L-T-K-I-K-G-S-R-N-K-H-N-V-A-R-A-T-V-E-A-L-K-L-L-R-T-A-E-Q-I-A-A-L-R-G-L-E-V-K-D-I-L-S"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-E-L-S-P-S-V-P-K-K-N-R-K-R-I-G-R-G-N-S-S-G-W-G-K-T-A-G-K-G-S-N-G-Q-N-S-R-A-G-G-G-V-K-P-Y-F-E-G-G-Q-M-P-I-Y-R-R-V-P-K-R-G-F-S-N-A-I-F-K-K-E-Y-T-V-I-S-L-A-F-L-N-E-N-F-E-D-G-E-E-V-S-L-E-T-L-F-N-K-C-L-I-K-K-G-R-D-G-V-K-V-L-G-N-G-E-L-N-K-K-L-T-V-K-V-H-K-I-S-K-S-A-K-A-A-V-E-A-K-G-G-T-V-E-L-V-E-V-K-G-F-E-R-A-E-T-N-K"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-N-K-N-F-E-E-Q-E-K-K-A-K-G-G-V-R-L-A-R-E-E-V-F-K-L-V-F-G-V-E-A-T-E-S-A-S-E-E-L-K-Q-A-F-D-I-Y-L-Q-N-S-E-E-L-I-G-T-L-N-E-N-Q-L-E-F-L-K-S-S-I-D-G-I-A-K-N-Y-D-N-I-K-D-I-I-K-K-N-T-Q-N-W-A-Y-E-R-I-G-V-V-E-R-A-L-L-I-V-A-T-Y-E-F-I-F-K-N-A-P-I-E-V-I-A-N-E-I-I-E-L-A-K-E-Y-G-N-E-K-S-Y-E-F-V-N-G-I-L-A-N-I-E-K-S-K-K"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-S-T-I-S-V-L-I-T-A-L-A-L-S-M-D-A-M-S-L-S-I-Y-Q-G-I-A-S-T-E-S-Q-K-K-Q-N-F-L-K-I-V-L-T-F-G-I-F-Q-F-A-M-A-L-V-G-S-L-S-G-I-L-F-I-H-Y-I-S-L-Y-S-K-Y-V-S-F-A-I-F-L-F-L-G-L-M-M-L-K-E-A-L-K-K-E-E-M-E-Y-D-E-K-Y-L-D-F-K-T-L-I-I-M-G-I-A-T-S-L-D-A-L-L-V-G-L-T-F-S-I-L-P-F-Y-Q-T-F-L-Y-T-V-E-I-G-V-I-T-A-I-I-A-G-L-G-F-I-L-G-D-K-F-G-N-I-L-G-Q-K-S-H-F-L-G-A-A-L-L-I-F-I-S-I-N-I-L-L"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-V-V-I-G-L-G-N-P-G-K-K-Y-E-K-T-R-H-N-I-G-F-I-A-V-D-N-L-R-K-K-F-N-I-S-D-E-R-E-K-F-Q-A-L-V-S-E-K-N-I-D-G-E-K-V-I-F-F-K-P-Q-T-F-M-N-L-S-G-N-S-V-I-E-I-I-N-F-Y-K-L-D-P-K-K-D-I-I-V-I-Y-D-D-M-D-L-S-F-G-D-I-R-I-R-E-K-G-S-S-G-G-H-N-G-I-K-S-I-I-S-H-I-G-E-E-F-I-R-I-K-C-G-I-G-A-K-E-R-D-A-V-E-H-V-L-G-E-F-N-Q-T-E-Q-K-D-L-D-E-I-L-E-K-I-N-N-C-V-I-E-M-L-S-V-Q-N-L-D-R-I-M-Q-K-Y-N-K-K-K-E-I-S-K"} +{"text": "### FUNCTION Might be a ribonuclease involved in RNA processing ### SEQUENCE -M-D-N-V-D-F-S-K-D-I-R-D-Y-S-G-L-E-L-A-F-L-G-D-A-I-W-E-L-E-I-R-K-Y-Y-L-Q-F-G-Y-N-I-P-T-L-N-K-Y-V-K-A-K-V-N-A-K-Y-Q-S-L-I-Y-K-K-I-I-N-D-L-D-E-E-F-K-V-I-G-K-R-A-K-N-S-N-I-K-T-F-P-R-S-C-T-V-M-E-Y-K-E-A-T-A-L-E-A-I-I-G-A-M-Y-L-L-K-K-E-E-E-I-K-K-I-I-N-I-V-I-K-G-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-R-A-A-V-K-R-D-V-L-P-D-S-R-Y-S-D-K-V-V-T-K-V-I-N-S-I-M-L-D-G-K-K-S-I-A-E-G-I-F-Y-S-A-M-D-L-I-K-E-K-T-G-Q-E-G-Y-D-I-F-K-Q-A-L-E-N-I-K-P-Q-I-E-V-R-S-R-R-I-G-G-A-T-Y-Q-V-P-V-E-V-K-A-D-R-Q-Q-T-L-A-I-R-W-L-T-T-Y-T-R-A-R-K-E-Y-G-M-I-E-K-L-A-A-E-L-I-A-A-A-N-N-E-G-A-T-I-K-K-K-E-D-T-Y-K-M-A-E-A-N-R-A-F-A-H-Y-R-V"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-V-G-L-G-N-P-G-F-E-Y-E-H-T-R-H-N-I-G-F-K-I-I-D-K-L-L-D-V-L-N-L-E-L-N-K-S-Q-F-N-G-L-Y-V-K-H-D-D-F-I-I-A-K-P-L-T-Y-M-N-L-S-G-N-F-I-R-Q-L-V-N-F-Y-K-I-Q-I-D-D-I-L-V-I-H-D-E-L-A-F-N-L-G-V-V-R-L-K-Q-N-G-S-A-N-G-Q-K-G-V-A-N-I-I-S-Q-L-G-T-Q-N-F-K-R-L-R-V-G-I-K-N-E-D-L-K-N-I-A-S-F-V-L-S-K-F-A-P-N-E-L-I-L-L-E-S-A-I-A-S-A-S-V-I-A-Y-D-F-L-K-S-N-K-S-F-S-K-L-M-N-E-Y-N-Q"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-L-L-V-A-K-K-E-I-T-R-I-A-K-L-E-L-I-G-G-Q-A-K-P-G-P-A-L-A-S-V-G-I-N-M-G-E-F-T-K-Q-F-N-E-K-T-K-D-R-M-G-D-V-V-P-V-I-I-T-A-F-N-D-K-S-F-L-F-E-L-K-T-T-P-V-T-V-L-L-K-K-A-A-K-I-E-S-G-A-K-N-P-K-T-E-K-V-G-K-I-S-K-A-E-A-L-K-I-A-E-Y-K-M-A-D-L-N-A-Y-D-T-E-A-A-L-R-M-I-A-G-T-A-K-Q-M-G-L-E-I-E-G-V-D-P-V-T-K-S-K-K-G-S"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-R-R-H-K-K-I-L-K-L-A-K-G-Y-Y-G-A-R-S-R-V-F-R-V-A-K-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-A-L-W-I-A-R-I-N-A-G-D-R-Q-N-G-L-S-Y-S-R-L-I-A-G-L-K-K-A-T-I-E-I-D-R-K-V-L-S-D-L-A-V-N-E-K-A-A-F-A-A-I-V-E-K-A-K-A-V-L-A"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-R-E-M-R-Q-D-R-K-A-Q-P-K-A-P-I-N-E-N-I-S-A-R-E-V-R-L-I-G-V-D-G-E-Q-I-G-I-V-S-I-D-E-A-L-R-V-A-E-E-A-K-L-D-L-V-E-I-S-A-D-A-V-P-P-V-C-R-I-M-D-Y-G-K-H-L-F-E-K-K-K-Q-V-A-A-A-K-K-N-Q-K-Q-V-Q-I-K-E-I-K-F-R-P-G-T-E-E-G-D-Y-Q-V-K-L-R-N-L-V-R-F-L-N-D-G-D-K-A-K-V-S-L-R-F-R-G-R-E-M-A-H-Q-E-L-G-M-E-L-L-K-R-V-E-N-D-L-A-E-F-G-T-V-E-Q-Y-P-K-L-E-G-R-Q-L-M-M-V-I-A-P-K-K-R-K"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-E-P-G-I-D-K-L-F-G-M-V-D-S-K-Y-R-L-T-V-V-V-A-K-R-A-Q-Q-L-L-R-H-G-F-K-N-T-V-L-E-P-E-E-R-P-K-M-Q-T-L-E-G-L-F-D-D-P-N-A-V-T-W-A-M-K-E-L-L-T-G-R-L-V-F-G-E-N-L-V-P-E-D-R-L-Q-K-E-M-E-R-L-Y-P-V-E-R-E-E"} +{"text": "### FUNCTION Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD As a transcriptional regulator, acts as an anti-FlhDC factor ### SEQUENCE -M-E-N-L-S-P-L-L-I-E-Y-Q-G-L-L-K-L-I-R-N-I-K-A-M-A-L-N-G-L-W-D-D-V-V-E-Q-E-I-V-Y-I-Q-S-I-E-R-I-S-Q-I-N-V-P-A-N-I-P-S-T-V-Q-L-Q-F-R-Q-L-L-Q-D-I-L-D-T-E-S-Q-V-K-E-L-L-Q-N-R-M-Q-E-L-A-V-L-I-Q-Q-S-Q-N-Q-K-S-I-N-N-T-Y-A-E-F-S-D-D-I-L-P-G-K-P-Q-P"} +{"text": "### FUNCTION This protein is a component of the reaction center of photosystem II ### SEQUENCE -M-S-E-G-G-K-I-P-L-W-I-V-A-V-V-A-G-M-G-V-I-A-V-V-G-I-F-F-Y-G-A-Y-A-G-V-G-S-A-V"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-E-R-N-Q-N-P-N-R-Q-P-V-E-L-N-R-T-S-L-Y-L-G-L-L-L-I-A-V-L-G-I-L-F-S-S-Y-F-F-N"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-V-T-S-I-M-D-D-L-K-R-R-M-D-G-A-I-S-A-F-K-H-E-L-S-G-L-R-T-G-R-A-S-A-S-L-L-E-P-L-T-V-E-A-Y-G-S-V-V-P-I-K-Q-V-A-N-I-S-V-L-E-P-R-M-L-S-V-S-V-W-D-K-T-M-V-G-A-V-E-R-A-I-R-D-C-G-F-G-L-N-P-I-V-D-G-M-N-L-R-I-P-L-P-E-L-N-E-E-R-R-K-E-L-V-K-I-A-H-Q-Y-A-E-Q-A-R-V-A-I-R-H-V-R-R-D-G-M-D-N-L-K-K-L-E-K-E-G-E-I-S-Q-D-E-A-R-S-L-S-E-K-V-Q-K-L-T-D-D-A-I-A-D-I-D-K-I-L-I-M-K-E-T-E-I-M-Q-V"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-S-Q-K-Q-E-V-V-A-E-L-A-D-I-A-A-K-A-H-S-L-I-A-A-E-Y-A-G-I-T-V-S-Q-M-T-A-M-R-K-Q-A-R-E-T-G-V-F-L-K-V-V-K-N-T-L-A-V-R-A-V-E-G-T-D-F-A-V-A-A-D-K-L-V-G-P-L-L-Y-A-F-S-M-E-E-P-G-A-A-G-R-L-I-K-E-F-A-K-G-N-D-K-L-Q-A-K-V-V-S-I-G-G-E-L-F-P-A-S-H-V-D-V-L-A-S-L-P-T-L-D-Q-A-L-A-M-L-A-R-V-L-S-E-P-A-A-M-F-A-R-A-V-K-A-V-G-D-K-Q-G-G-G-D-E-A-A-A-P-V-A-E-T-A-E-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-V-A-L-I-K-L-Q-V-K-A-G-Q-A-N-P-A-P-P-V-G-P-A-L-G-Q-R-G-L-N-I-M-E-F-C-K-A-F-N-A-A-T-S-K-L-E-P-G-L-P-T-P-V-I-I-T-A-Y-S-D-R-T-F-T-F-I-T-K-S-T-P-A-S-V-L-L-K-K-A-A-G-V-S-S-G-S-K-R-P-N-T-D-K-V-G-K-V-T-R-K-Q-L-E-E-I-V-K-V-K-E-A-D-L-T-A-A-E-L-E-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-T-V-E-G"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-I-E-A-I-S-K-D-E-M-T-A-S-G-I-V-L-P-D-S-A-K-E-K-P-Q-E-G-R-V-I-A-V-G-S-G-R-V-A-D-N-G-E-R-I-A-L-E-V-K-D-G-D-K-V-I-F-S-K-Y-A-G-T-E-V-K-V-D-N-K-E-Y-L-V-L-R-E-S-D-I-L-A-I-I-G"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-I-N-Q-L-I-R-N-T-R-Q-P-I-R-N-V-T-K-S-P-A-L-R-G-C-P-Q-R-R-G-T-C-T-R-V-Y-T-I-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-I-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-A-V-G-V-K-D-R-Q-Q-G-R-S-K-Y-G-V-K-K-P-K"} +{"text": "### FUNCTION Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner ### SEQUENCE -M-A-T-P-F-I-A-G-V-A-V-A-A-T-A-L-A-G-R-Y-G-I-Q-A-W-Q-A-F-K-A-R-P-P-R-P-K-I-K-K-F-Y-E-G-G-F-Q-P-T-M-T-K-R-E-A-A-L-I-L-G-V-R-E-S-V-A-A-E-K-V-K-E-A-H-R-K-V-M-V-A-N-H-P-D-A-G-G-S-H-F-L-A-S-K-I-N-E-A-K-D-V-M-L-G-K-T-K-N-S-G-S-A-F"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-V-A-A-T-A-E-F-R-R-V-F-S-A-F-D-R-D-A-D-G-K-I-S-A-A-E-L-R-L-C-M-K-A-A-L-G-E-D-M-S-A-E-E-A-E-A-L-V-S-S-A-D-T-D-D-D-G-L-L-D-E-E-E-F-T-K-L-A-V-Q-L-E-M-G-D-E-E-E-R-C-R-G-L-M-E-A-F-R-M-Y-E-M-E-G-E-G-R-I-T-P-A-S-L-K-R-M-L-S-K-L-G-S-H-Q-G-I-E-E-C-Q-T-M-I-C-R-F-D-L-D-G-D-G-V-I-S-F-E-E-F-K-I-M-M-D-A"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-V-A-S-D-E-F-R-R-V-F-G-S-F-D-Q-D-G-D-G-K-I-S-A-T-E-L-R-L-C-V-K-A-S-L-G-E-D-M-P-D-E-E-V-Q-A-L-M-A-L-A-D-T-D-G-D-G-L-L-D-E-E-E-F-V-R-L-V-T-E-M-E-A-D-G-D-E-E-E-D-D-D-D-E-T-C-R-C-L-R-E-A-F-A-M-Y-E-M-E-G-R-G-C-I-T-P-L-S-L-K-L-M-L-S-K-L-G-T-H-L-D-V-A-E-C-Q-A-M-I-C-R-F-D-M-N-G-D-G-V-L-T-F-D-E-F-K-T-M-M-M-A"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-V-V-A-S-A-A-S-P-C-E-S-S-A-L-F-A-T-F-D-H-D-G-D-G-R-I-S-A-A-E-L-R-L-C-M-K-T-T-L-G-E-E-V-S-D-E-E-A-G-Q-L-V-A-S-V-D-A-D-G-D-G-L-L-C-E-A-E-F-V-R-L-V-Q-A-A-E-V-E-E-E-D-E-R-R-G-T-G-L-R-E-A-F-G-M-Y-E-M-E-G-E-G-C-I-T-P-T-S-L-R-R-M-L-R-R-L-G-S-D-Q-D-I-D-D-C-R-A-M-I-C-R-F-D-L-N-G-D-G-V-L-S-F-D-E-F-K-I-M-M-N-A"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-V-K-I-K-M-P-A-L-F-R-R-R-S-G-S-K-S-P-P-L-P-Q-A-D-P-A-S-G-G-G-S-P-A-P-T-P-E-E-E-M-E-R-V-F-R-K-F-D-A-N-G-D-G-R-I-S-R-S-E-L-G-A-L-F-E-S-L-G-H-A-A-T-D-D-E-L-A-R-M-M-A-E-A-D-A-D-G-D-G-F-I-S-L-D-E-F-A-A-L-N-A-T-A-S-G-D-A-A-A-V-E-E-D-L-R-H-A-F-R-V-F-D-A-D-G-N-G-T-I-S-A-A-E-L-A-R-V-L-H-G-L-G-E-K-A-T-V-Q-Q-C-R-R-M-I-E-G-V-D-Q-N-G-D-G-L-I-S-F-E-E-F-K-V-M-M-A-G-G-G-S-F-A-K-I-A"} +{"text": "### FUNCTION Thiol-disulfide oxidoreductase involved in the redox regulation of enzymes of both reductive pentose phosphate pathway and oxidative pentose phosphate pathway ### SEQUENCE -M-A-L-R-L-S-V-S-S-S-H-G-P-A-S-S-P-A-I-S-T-C-R-P-A-A-C-G-R-F-P-A-L-L-G-G-G-V-A-S-Q-R-R-S-L-T-V-V-S-G-P-E-T-R-A-V-I-P-V-R-S-S-G-S-D-T-A-T-V-G-A-E-A-E-A-V-A-V-T-G-Q-V-T-E-V-N-K-D-T-F-W-P-I-V-K-S-A-G-P-K-V-V-V-L-D-M-Y-T-Q-W-C-G-P-C-K-V-M-A-P-K-F-Q-E-M-S-E-K-D-Q-D-V-V-F-L-K-L-D-C-N-Q-D-N-K-S-L-A-K-E-L-G-I-K-V-V-P-T-F-K-I-L-K-D-G-K-V-V-K-E-V-T-G-A-K-L-D-E-L-I-Q-A-I-E-T-V-K-S-S"} +{"text": "### FUNCTION Probable transcription factor ### SEQUENCE -M-G-R-G-R-S-E-I-K-R-I-E-N-P-T-Q-R-Q-S-T-F-Y-K-R-R-D-G-L-F-K-K-A-R-E-L-A-V-L-C-D-A-D-L-L-L-L-L-F-S-A-S-G-K-L-Y-H-F-L-S-P-T-V-P-S-V-R-E-F-V-E-R-Y-E-A-T-T-H-T-K-V-W-A-D-I-R-Q-E-R-R-A-E-L-E-K-V-G-S-M-C-D-L-L-E-K-Q-L-R-F-M-T-V-D-D-G-E-E-Y-T-V-P-S-L-E-A-L-E-H-N-L-E-A-A-M-R-K-V-R-S-E-K-D-R-K-I-G-G-E-I-C-Y-L-Q-N-I-I-R-G-R-Q-E-E-R-Y-G-L-C-D-K-I-A-H-A-Q-T-L-K-D-V-E-C-G-S-T-S-L-S-N-G-L-D-L-K-L-G-F-N"} +{"text": "### FUNCTION E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage ### SEQUENCE -M-E-G-W-D-K-G-T-K-S-V-V-G-E-I-P-L-L-S-T-R-A-G-P-R-D-G-E-A-W-R-Q-R-L-K-E-E-Y-R-A-L-I-A-Y-T-S-V-N-K-S-K-D-N-D-W-F-R-I-S-A-A-N-P-E-G-T-R-W-E-G-T-C-W-Y-V-H-N-L-R-R-Y-E-F-P-L-Q-F-D-I-P-V-A-Y-P-Q-V-A-P-E-I-E-L-P-T-L-D-G-K-T-H-K-M-Y-R-G-G-K-I-C-L-T-V-H-F-K-P-L-W-A-K-N-C-P-R-F-G-I-A-H-A-L-C-L-G-L-A-P-W-L-A-A-E-V-P-I-L-V-D-S-G-M-V-K-H-K-D-D-E-A-A-P-A-D-A-A-A-A-A-S-G-S-A-A-A-S"} +{"text": "### FUNCTION May play a role during anther development ### SEQUENCE -M-A-D-C-T-T-M-R-L-A-S-S-V-T-I-I-L-L-L-L-V-A-S-Q-A-L-V-V-S-G-E-S-S-S-S-A-M-Q-S-K-T-L-N-M-N-K-L-L-N-I-S-E-D-H-S-P-N-G-G-R-H-W-M-Q-R-M-Q-P-D-S-C-S-E-Q-N-V-V-V-Y-Q-N-N-A-E-H-L-P-S-G-I-P-T-Y-S-V-E-I-I-N-V-C-T-A-C-T-V-Y-D-V-H-I-S-C-G-E-F-A-S-A-E-L-V-D-P-S-Q-F-Q-R-I-G-F-N-D-C-L-V-K-G-G-G-R-L-G-P-S-E-A-V-S-F-Q-Y-S-N-S-F-A-Y-P-L-A-V-A-N-V-A-C-E"} +{"text": "### FUNCTION Component of the central CCA1/LHY-TOC1 feedback loop in the circadian clock that promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles ### SEQUENCE -M-E-G-D-T-I-S-R-M-M-G-S-G-V-Q-M-D-G-K-I-L-Q-T-F-E-K-S-F-V-Q-V-Q-N-I-L-D-H-N-R-L-L-I-N-E-I-N-Q-N-H-E-S-K-I-P-D-N-L-G-R-N-V-G-L-I-R-E-L-N-N-N-V-R-R-V-A-H-L-Y-V-D-L-S-N-N-F-S-K-S-M-E-A-S-S-E-G-D-S-S-E-G-R-G-N-R-R-I-R-P-A"} +{"text": "### FUNCTION Promotes cellular proliferation and expansion ### SEQUENCE -M-G-Y-S-S-S-S-R-I-G-L-C-L-F-L-F-F-T-F-A-L-L-S-S-A-R-I-S-L-S-F-S-E-N-E-M-T-V-V-P-E-R-S-L-M-V-S-T-N-D-Y-S-D-P-T-A-N-G-R-H-D-P-P-R-G-G-R-G-R-R-R"} +{"text": "### FUNCTION Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites ### SEQUENCE -M-A-S-S-S-S-L-T-R-S-G-S-V-H-L-D-E-K-W-K-L-S-K-K-D-G-G-A-S-R-I-T-R-S-S-S-T-S-S-S-S-F-N-G-K-K-Q-G-R-C-A-F-T-R-K-C-A-R-L-V-K-E-Q-R-A-R-F-Y-I-M-R-R-C-V-I-M-L-I-C-W-R-D-N-Y-S-D-S"} +{"text": "### FUNCTION May be involved in cadmium resistance ### SEQUENCE -M-K-E-K-K-G-H-Y-V-P-P-S-Y-I-P-L-T-Q-S-D-A-D-T-E-V-E-T-T-T-P-N-L-E-I-A-V-S-E-S-T-K-D-D-P-R-Q-W-S-S-G-I-C-A-C-F-D-D-M-Q-S-C-C-V-G-L-F-C-P-C-Y-I-F-G-K-N-A-E-L-L-G-S-G-T-F-A-G-P-C-L-T-H-C-I-S-W-A-L-V-N-T-I-C-C-F-A-T-N-G-A-L-L-G-L-P-G-C-F-V-S-C-Y-A-C-G-Y-R-K-S-L-R-A-K-Y-N-L-Q-E-A-P-C-G-D-F-V-T-H-F-F-C-H-L-C-A-I-C-Q-E-Y-R-E-I-R-E-Q-S-S-G-S-Y-P-L-D-M-K-M-A-I-T-N-A-P-L-A-Q-T-M-E-S-A-N"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-L-K-K-K-K-T-E-V-Y-A-L-G-E-H-I-S-M-S-A-D-K-A-R-R-V-I-D-Q-I-R-G-R-S-Y-E-E-T-L-M-I-L-E-L-M-P-Y-R-A-C-Y-P-I-L-K-L-V-Y-S-A-A-A-N-A-S-Y-N-M-G-S-S-E-A-N-L-V-I-S-K-A-E-V-N-G-G-T-T-V-K-K-L-K-P-R-A-R-G-R-S-F-P-I-K-R-S-T-C-H-I-T-I-V-M-K-D-I-S-L-N-D-E-Y-V-K-M-N-S-L-K-K-T-R-W-K-K-K-S-T-A-M-T-Y-H-D-M-Y-N-S-G-G-L-W-D-K-K"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-P-Q-T-H-L-N-V-A-D-N-S-G-A-R-E-L-M-C-I-R-I-I-G-A-S-N-R-R-Y-A-H-I-G-D-V-I-V-A-V-I-K-E-A-V-P-N-M-P-L-E-R-S-E-I-V-R-A-V-I-V-R-T-C-K-E-L-K-R-D-N-G-M-I-I-R-Y-D-D-N-A-A-V-V-I-D-Q-E-G-N-P-K-G-T-R-I-F-G-A-I-A-R-E-L-R-E-L-N-F-T-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-R-D-T-I-A-E-I-I-T-S-I-R-N-A-D-M-D-R-K-R-V-V-R-I-A-S-T-N-I-T-E-N-I-V-Q-I-L-L-R-E-G-F-I-E-N-V-R-K-H-Q-E-N-N-K-Y-F-L-V-L-T-L-R-H-R-R-N-K-K-R-P-Y-R-N-I-L-N-L-K-R-I-S-R-P-G-L-R-I-Y-S-N-Y-Q-R-I-P-R-I-L-G-G-M-G-I-V-I-L-S-T-S-R-G-I-M-T-D-R-E-A-R-L-E-G-I-G-G-E-I-L-C-Y-I-W"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-L-P-T-K-K-N"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-R-D-L-K-T-Y-L-S-V-A-P-V-L-S-T-L-W-F-V-A-L-A-G-L-L-I-E-I-N-R-F-F-P-D-A-L-T-F-P-F-F"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-T-W-R-S-E-H-I-W-I-E-L-I-T-G-S-R-K-I-S-N-F-C-W-A-F-I-L-F-L-G-S-L-G-F-L-L-V-G-T-S-S-Y-L-G-R-N-L-I-S-F-F-P-T-Q-Q-I-V-F-F-P-Q-G-I-V-M-S-F-Y-G-I-A-G-L-F-I-S-S-Y-L-W-C-T-I-S-W-N-V-G-S-G-Y-D-R-F-D-R-K-E-G-I-V-C-I-F-R-W-G-F-P-G-K-N-R-R-I-F-L-R-F-L-I-K-D-I-Q-S-V-R-I-E-V-K-E-G-I-S-A-R-R-V-L-Y-M-D-I-R-G-Q-G-S-I-P-L-T-R-T-D-E-N-L-T-P-R-E-I-E-Q-K-A-A-E-L-A-Y-F-L-R-V-P-I-E-V-F"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-T-L-N-L-S-V-L-T-P-N-R-I-V-W-D-S-E-V-E-E-I-V-L-S-T-N-S-G-Q-I-G-I-L-S-N-H-A-P-I-A-T-A-V-D-I-G-I-L-R-I-R-L-N-D-Q-W-L-T-M-A-L-M-G-G-F-A-R-I-G-N-N-E-I-T-V-L-V-N-D-A-E-K-G-S-D-I-D-P-Q-E-A-Q-Q-T-L-E-I-A-E-A-N-V-K-K-A-E-G-R-R-Q-K-I-E-A-N-L-A-L-R-R-A-R-T-R-V-E-A-I-N-P-I-S"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-R-I-N-G-N-F-I-D-Q-T-F-S-I-V-A-N-I-L-L-R-V-I-P-T-T-S-G-E-K-E-A-F-T-Y-Y-R-D-G-M-S-A-Q-S-E-G-N-Y-A-E-A-L-Q-N-Y-Y-E-A-M-R-L-E-I-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-E-H-T-K-A-L-E-Y-Y-F-R-A-L-E-R-N-P-F-L-P-Q-A-F-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-Q-Q-G-D-S-E-I-A-E-A-W-F-D-Q-A-A-E-Y-W-K-Q-A-I-A-L-T-P-G-N-Y-I-E-A-H-N-W-L-K-I-T-R-R-F-E"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-N-V-T-D-S-F-V-S-L-G-H-W-P-S-A-G-S-F-G-F-N-T-D-I-L-A-T-N-P-I-N-L-S-V-V-L-G-V-L-I-F-F-G-K-G-V-L-S-D-L-L-D-N-R-K-Q-R-I-L-N-T-I-R-N-S-E-E-L-R-E-G-A-I-E-Q-L-E-K-A-R-S-R-L-R-K-V-E-T-E-A-E-Q-F-R-V-N-G-Y-S-E-I-E-R-E-K-L-N-L-I-N-S-T-Y-K-T-L-E-Q-L-E-N-Y-K-N-E-T-I-Q-F-E-Q-Q-R-A-I-N-Q-V-R-Q-R-V-F-Q-Q-A-L-R-G-A-L-G-T-L-N-S-C-L-N-N-E-L-H-L-R-T-I-S-A-N-I-G-M-L-G-T-M-K-E-I-T-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-N-T-F-S-L-I-G-I-C-L-N-S-T-L-Y-S-S-S-F-F-F-G-K-L-P-E-A-Y-A-F-L-N-P-I-V-D-I-M-P-V-I-P-L-F-F-F-L-L-A-F-V-W-Q-A-A-V-S-F-R"} +{"text": "### FUNCTION Involved in the transport of copper ### SEQUENCE -M-L-S-S-K-N-V-V-V-V-E-A-W-N-T-T-T-T-T-Q-T-Q-T-P-H-R-P-S-L-L-H-P-T-F-Y-W-G-Y-N-C-Q-V-L-F-S-G-W-P-G-S-D-R-G-M-Y-A-L-A-L-I-F-V-F-F-L-A-F-L-A-E-W-L-A-R-C-S-D-A-S-S-I-K-Q-G-A-D-K-L-A-K-V-A-F-R-T-A-M-Y-T-V-K-S-G-F-S-Y-L-V-I-L-A-V-V-S-F-N-G-G-V-F-L-A-A-I-F-G-H-A-L-G-F-A-V-F-R-G-R-A-F-R-N-R-D-I-Q"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-D-H-L-M-C-E-V-D-G-N-P-G-Q-Q-L-S-A-A-A-I-I-G-H-D-G-S-V-W-A-Q-S-S-T-F-P-K-F-K-P-E-E-I-T-G-I-M-K-N-F-D-E-P-G-H-L-A-P-T-G-L-Y-L-G-G-T-K-Y-M-V-I-Q-G-E-P-I-A-V-I-R-G-K-K-G-S-G-G-V-T-I-K-K-T-G-Q-A-L-V-F-G-V-Y-D-E-P-V-T-P-G-Q-C-N-L-I-V-E-R-L-G-D-Y-L-I-E-Q-G-L"} +{"text": "### FUNCTION Actin-depolymerizing protein Severs actin filaments ### SEQUENCE -M-S-F-R-G-L-N-A-S-S-G-M-G-V-A-D-H-S-K-N-T-F-L-E-L-K-R-K-K-V-H-R-Y-V-I-F-K-I-D-E-K-K-K-E-V-V-V-E-K-T-G-G-P-A-E-S-F-D-E-F-A-A-A-L-P-E-N-D-C-R-Y-A-V-Y-D-F-D-F-V-T-S-E-N-C-Q-K-S-K-I-F-F-I-A-W-S-P-D-S-S-R-I-R-A-K-M-L-Y-A-T-S-K-E-R-F-R-R-E-L-D-G-V-H-Y-E-I-Q-A-T-D-P-T-E-M-D-L-E-V-L-R-E-R-A-H"} +{"text": "### FUNCTION Potent plasminogen activator that converts plasminogen into plasmin It forms a 11 complex with plasmin, which in turn activates other plasminogen molecules ### SEQUENCE -M-L-K-R-S-L-L-F-L-T-V-L-L-L-L-F-S-F-S-S-I-T-N-E-V-S-A-S-S-S-F-D-K-G-K-Y-K-K-G-D-D-A-S-Y-F-E-P-T-G-P-Y-L-M-V-N-V-T-G-V-D-G-K-G-N-E-L-L-S-P-H-Y-V-E-F-P-I-K-P-G-T-T-L-T-K-E-K-I-E-Y-Y-V-E-W-A-L-D-A-T-A-Y-K-E-F-R-V-V-E-L-D-P-S-A-K-I-E-V-T-Y-Y-D-K-N-K-K-K-E-E-T-K-S-F-P-I-T-E-K-G-F-V-V-P-D-L-S-E-H-I-K-N-P-G-F-N-L-I-T-K-V-I-I-E-K-K"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-S-L-T-L-V-L-F-L-I-G-I-L-G-F-V-F-N-R-K-N-I-I-L-M-L-I-S-I-E-I-M-L-L-S-I-T-F-L-I-L-V-S-S-I-N-L-D-D-I-I-G-Q-T-Y-A-I-Y-I-I-V-V-A-G-A-E-S-A-I-G-L-A-I-L-V-A-F-Y-R-L-R-G-S-I-A-I-E-Y-K"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -N-G-W-N-D-N-K-T-F-I-L-I-G-S-A-S-W-A-A-L-V-L-L-V-G-S-L-N-S-F-V-I"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -N-G-W-N-E-N-K-N-F-I-L-L-G-A-V-T-W-A-I-L-V-F-I-V-G-S-L-N-S-Y-V-I"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -N-S-W-E-N-N-K-N-I-I-F-S-G-S-L-I-W-V-F-L-L-I-I-V-G-F-L-N-Y-L-V-V"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -N-G-W-N-D-N-K-N-F-V-L-F-G-A-A-A-W-I-G-L-V-L-L-V-G-T-L-Y-Y-F-V-V"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -N-G-W-N-E-N-K-N-Y-I-L-I-G-S-A-A-W-A-G-L-V-L-L-V-G-T-L-N-Y-L-V-I"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase , that is believed not to be involved in catalysis Complex I functions in the transfer of electrons from NADH to the respiratory chain The immediate electron acceptor for the enzyme is believed to be ubiquinone ### SEQUENCE -M-W-F-E-I-L-P-G-L-S-V-M-G-V-C-L-L-I-P-G-L-A-T-A-Y-I-H-R-F-T-N-G-G-K-E-K-R-V-A-H-F-G-Y-H-W-N-L-M-E-R-D-R-R-I-S-G-V-D-R-Y-Y-V-S-K-G-L-E-N-I-D"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase , that is believed not to be involved in catalysis but required for the complex assembly Complex I functions in the transfer of electrons from NADH to the respiratory chain The immediate electron acceptor for the enzyme is believed to be ubiquinone ### SEQUENCE -M-V-P-R-R-N-P-E-P-L-R-F-L-P-D-E-S-R-S-L-P-P-P-K-L-T-D-P-R-L-L-Y-V-G-F-L-G-Y-C-A-G-L-V-D-N-F-I-H-R-R-P-I-R-S-A-G-L-H-R-H-L-L-Y-I-T-A-F-Y-F-V-G-Y-Y-L-V-K-R-G-D-Y-T-Y-A-V-R-D-R-E-M-F-G-Y-M-K-L-H-P-E-D-F-S-E-K-E-K-K-T-Y-A-E-I-F-E-K-F-H-P-I-R"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase , that is believed not to be involved in catalysis Complex I functions in the transfer of electrons from NADH to the respiratory chain The immediate electron acceptor for the enzyme is believed to be ubiquinone ### SEQUENCE -M-W-F-E-I-L-P-G-I-A-V-M-G-T-C-L-V-I-P-G-L-A-T-A-Y-I-H-R-F-T-N-G-G-K-E-K-R-V-A-H-F-V-Y-H-W-D-L-M-E-R-D-R-H-I-S-G-V-N-R-Y-Y-V-S-K-G-L-E-N-I-D"} +{"text": "### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-S-P-S-V-A-L-A-V-L-A-L-L-S-L-S-G-L-E-A-I-Q-R-T-P-K-I-Q-V-Y-S-R-H-P-P-E-N-G-K-P-N-F-L-N-C-Y-V-S-G-F-H-P-S-D-I-E-V-D-L-L-K-N-G-E-K-M-G-K-V-E-H-S-D-L-S-F-S-K-D-W-S-F-Y-L-L-Y-Y-T-E-F-T-P-N-E-K-D-E-Y-A-C-R-V-N-H-V-T-L-S-G-P-R-T-V-K-W-D-R-D-M"} +{"text": "### FUNCTION Receptor for gonadotropin releasing hormone This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system ### SEQUENCE -V-A-F-A-T-S-F-T-V-C-W-T-P-Y-Y-V-L-G-I-W-Y-W-F-D-P-E-M-L-N-R-V-S-D-P-V-N-H-F-F-F-L-F-A-F-L-N-P-C-F-D-P-L-I-Y-G-Y-F-S-L"} +{"text": "### FUNCTION Has a low ribonuclease activity ### SEQUENCE -M-A-P-A-R-E-G-C-C-P-L-L-L-L-L-L-L-G-L-W-V-A-E-I-P-V-S-A-K-P-E-G-M-T-S-S-Q-W-F-N-T-Q-H-V-Q-P-S-P-Q-A-C-D-S-A-M-R-D-I-N-K-H-T-K-R-C-K-D-L-N-T-F-L-H-K-P-F-S-S-V-A-A-T-C-Q-T-P-N-I-T-C-K-N-G-H-K-N-C-H-Q-S-H-R-P-V-S-L-T-M-C-G-L-T-S-G-K-Y-P-N-C-R-Y-K-E-E-H-Q-N-K-S-Y-V-V-A-C-E-P-P-Q-Q-G-D-P-E-H-S-L-V-P-V-H-F-D-K-V-V"} +{"text": "### FUNCTION Has a low ribonuclease activity ### SEQUENCE -M-A-P-A-R-A-G-C-C-P-L-L-L-L-L-L-G-L-W-V-A-Q-I-P-V-S-A-K-P-K-D-M-T-S-S-Q-W-F-K-T-Q-H-V-Q-P-S-P-E-A-C-Y-L-A-M-S-N-I-S-K-Y-I-E-W-C-K-D-L-N-T-F-L-H-E-P-F-S-S-V-A-T-T-C-Q-T-P-N-I-A-C-K-N-G-H-K-N-C-H-Q-S-S-G-P-M-S-L-T-M-C-E-L-T-S-G-K-Y-P-N-C-R-Y-K-E-K-H-L-N-A-P-Y-I-V-A-R-D-P-P-Q-Q-G-D-P-G-Y-P-L-V-P-V-H-L-D-K-V-V"} +{"text": "### FUNCTION Has a low ribonuclease activity ### SEQUENCE -M-A-P-A-R-A-G-C-C-P-L-L-L-L-L-L-G-L-R-V-A-Q-I-P-V-S-A-K-P-K-D-M-T-S-S-Q-W-F-K-T-Q-H-V-Q-P-S-P-E-A-C-Y-S-A-M-S-N-I-S-K-Y-I-E-W-C-K-D-L-N-T-F-L-H-E-P-F-S-S-V-A-T-T-C-Q-T-P-N-I-A-C-K-N-R-H-K-N-C-H-Q-S-S-G-P-M-S-L-T-M-C-E-L-T-S-G-K-Y-P-N-C-R-Y-K-E-K-H-L-N-A-P-Y-I-V-A-C-D-P-P-Q-Q-G-D-P-G-Y-P-L-V-P-V-H-L-D-K-V-V"} +{"text": "### FUNCTION Binds specifically to the 3'-terminal U-tract of U6 snRNA ### SEQUENCE -M-L-D-P-F-C-F-L-K-M-Y-L-K-E-R-V-E-V-K-T-K-S-G-E-A-Y-T-G-T-L-E-G-F-D-E-H-I-N-L-M-L-T-C-S-S-V-E-G-S-E-D-K-V-L-F-L-R-G-E-N-I-L-F-V-G-P-R-L-L-L"} +{"text": "### FUNCTION Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner LSM2 binds specifically to the 3'-terminal U-tract of U6 snRNA Required for processing of pre-tRNAs, pre-rRNAs and U3 snoRNA ### SEQUENCE -M-L-F-Y-E-F-F-R-S-S-I-G-S-R-V-S-V-M-L-K-A-G-V-Y-V-S-G-R-L-G-G-I-D-P-Y-L-N-L-S-L-L-D-V-R-I-L-S-S-H-P-G-L-S-S-I-S-V-C-S-I-R-G-S-S-I-K-Y-I-L-V-D-K-D-A-K-L-L-Q-G-V-N-A-G-S-R-L-R-M-I-L-D-K-C-Y"} +{"text": "### FUNCTION Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane It must be involved intimately in the translocation of a wide variety of protein substrates ### SEQUENCE -M-E-S-K-H-F-C-L-Y-P-I-Y-M-D-S-A-R-S-L-S-E-G-R-K-Y-R-K-E-I-C-V-Q-R-P-R-Y-H-E-I-K-N-A-L-E-K-L-E-I-E-Y-T-D-E-P-S-K-K-H-P-R-D-F-F-N-S-G-R-F-R-I-K-K-E-Y-G-R-L-F-V-I-E-G-I-S-Q-T-I-A-E-L-R-S-K-P-G-S-S-E-E-T-S-R-E-K-Q-S-R-G-K-A-V-H-G-V-V-Q-N-G-V-Y-V-E-N-K-L-N-L-V-R-K-K-K-A-K-K-K-K"} +{"text": "### FUNCTION The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins ### SEQUENCE -M-N-L-F-D-I-E-G-L-L-V-A-D-S-Q-G-E-I-L-Y-R-R-V-F-S-K-E-E-E-I-A-A-K-I-A-E-K-A-A-G-D-R-E-S-I-S-M-F-Y-D-R-I-V-M-C-K-R-L-D-E-V-L-L-I-I-Y-S-P-M-D-V-N-E-P-F-V-G-Q-V-F-D-E-F-T-A-A-F-I-G-I-V-K-T-P-T-R-E-R-V-W-K-K-Y-D-Q-I-V-L-L-V-A-E-F-L-Y-E-G-I-V-M-S-G-K-S-D-E-M-L-D-K-L-P-K-R-N-F-E-G-V-D-G-M-K-V-P-R-G-F-A-S-F-L-H-K-A-T-K-S-L-S-I-G-S-N-K"} +{"text": "### FUNCTION Non-catalytic component of the proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus It is essential for the regulated turnover of proteins and for the removal of misfolded proteins The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH It has an ATP-dependent proteolytic activity ### SEQUENCE -M-D-S-S-I-G-I-K-G-R-N-F-A-I-V-A-A-D-T-K-I-S-S-S-I-L-V-V-K-E-N-H-E-K-F-Q-V-I-K-D-R-I-V-M-A-M-T-G-N-Q-G-D-A-F-R-T-M-L-Y-V-S-E-S-A-L-Y-E-E-I-Q-N-G-I-E-L-S-P-S-V-L-A-H-M-I-Q-N-K-V-H-E-S-L-R-R-R-Q-L-D-I-S-S-I-V-A-G-R-G-P-E-K-Y-D-L-W-S-V-D-K-Y-G-A-I-S-S-V-P-F-C-A-S-G-Y-A-A-Y-F-V-Y-G-I-L-D-R-E-Y-S-E-D-I-T-I-D-A-A-L-S-I-M-Q-K-C-V-N-L-L-K-E-R-L-M-I-N-L-E-G-F-M-V-K-I-V-T-D-D-G-I-L-T-R-T-L-V-P-E-I-K-G"} +{"text": "### FUNCTION Plays an important role in the elongation step of protein synthesis ### SEQUENCE -M-E-Y-V-A-A-Y-V-M-F-D-K-V-G-K-E-L-N-E-R-S-M-T-E-L-F-N-E-I-G-A-E-I-E-P-E-T-M-R-L-F-L-S-K-V-S-G-K-S-M-D-E-V-M-S-K-G-K-E-L-M-A-S-L-A-I-S-S-S-Q-K-S-E-P-A-Q-P-A-D-T-A-E-S-T-Q-A-T-E-N-K-E-E-E-D-E-D-F-D-I-F-A-A-F"} +{"text": "### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively Pol II is the central component of the basal RNA polymerase II transcription machinery Pols are composed of mobile elements that move relative to each other In Pol II, RBP10 is part of the core element with the central large cleft ### SEQUENCE -M-I-I-P-I-R-C-F-T-C-G-K-E-I-S-S-K-W-E-P-Y-Q-E-L-L-K-I-D-K-G-K-A-E-A-L-D-E-L-G-M-R-R-I-C-C-R-R-M-F-L-G-H-V-D-I-V-D-K-L-L-K-F-D-I-V-K-D-F-T-Q-R-S"} +{"text": "### FUNCTION Necessary for protein translocation in the endoplasmic reticulum ### SEQUENCE -M-S-Q-K-L-Q-K-P-S-F-L-S-E-Y-L-R-S-I-R-L-F-S-K-K-C-V-R-P-S-G-K-E-L-S-M-S-I-K-R-H-A-I-G-I-G-F-L-G-I-L-G-Y-A-I-K-L-I-H-I-P-I-N-N-I-I-V-S-S-P-G-K-E"} +{"text": "### FUNCTION Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione ### SEQUENCE -M-E-R-G-M-E-S-E-A-F-Y-G-L-S-A-R-G-W-D-G-S-E-V-S-L-G-S-F-R-G-C-V-I-M-I-A-N-V-A-S-S-C-K-F-A-E-S-N-Y-K-S-F-A-G-L-L-D-K-F-Y-R-K-G-L-R-I-L-L-F-P-C-N-Q-Y-L-G-Q-E-S-R-P-I-E-E-I-R-G-E-V-S-K-K-Y-S-D-R-F-V-V-F-D-K-V-D-V-F-G-K-G-A-H-P-V-F-R-H-L-V-N-T-K-N-G-K-G-R-L-G-N-F-I-K-W-N-F-T-K-F-L-V-D-R-K-G-C-V-V-K-R-F-G-P-S-D-I-V-K-E-D-D-E-N-L-L-R-S-I-E-D-G-E-N-G-M-Q-N-S"} +{"text": "### FUNCTION Functions as a component of the DNA-binding general transcription factor complex TFIID May also function as a component of transcription regulatory histone acetyl transferase ### SEQUENCE -M-A-S-G-E-N-L-A-P-R-D-A-K-V-I-S-V-I-L-R-S-L-G-I-E-E-C-E-P-K-V-I-I-Q-L-L-E-F-A-Y-R-Y-T-T-D-V-L-E-D-A-L-L-F-A-K-H-T-G-R-T-H-I-T-T-S-D-V-K-L-A-L-Q-T-K-V-G-R-H-F-V-P-P-P-P-R-Q-Y-L-S-E-I-S-T-M-V-N-S-K-P-L-T-I-P-D-G-E-N-L-I-R-V-P-P-S-S-S-A-L-L-N-L-D-Y-E-V-L-R-K-D-S-D-K-K-R-R-I-Y"} +{"text": "### FUNCTION Seems to be involved in N-acetylation ### SEQUENCE -M-T-T-I-R-R-F-V-C-D-D-L-F-K-F-N-N-I-N-L-D-Y-L-T-E-T-Y-Y-L-P-F-Y-L-Q-Y-L-S-K-W-P-S-L-L-S-M-A-E-D-V-N-G-K-P-M-G-Y-M-I-G-K-A-E-G-E-G-I-N-W-H-G-H-V-T-A-V-S-V-A-P-E-F-R-R-I-G-L-A-D-R-L-M-H-I-L-E-E-G-S-E-K-I-Y-D-G-Y-F-V-D-L-F-V-R-K-S-N-T-L-A-I-N-M-Y-T-K-F-G-Y-S-V-Y-R-T-V-I-G-Y-Y-S-G-D-E-D-A-L-D-M-R-K-A-L-P-R-D-V-E-K-K-S-I-I-P-L-K-H-P-V-Y-P-T-D-A-D-L"} +{"text": "### FUNCTION Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca complex are a number of protein kinases and phosphatases ### SEQUENCE -M-S-Q-E-L-T-I-N-A-D-Q-L-T-E-E-Q-I-A-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-T-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-Q-D-M-I-N-E-V-D-A-D-G-N-G-T-I-D-F-P-E-F-L-T-M-M-A-R-K-M-K-D-T-D-S-E-E-E-I-R-E-A-F-R-V-F-D-K-D-G-N-G-F-I-S-A-A-E-L-R-H-V-M-T-N-L-G-E-K-L-T-D-E-E-V-D-E-M-I-R-E-A-D-I-D-G-D-G-Q-V-N-Y-E-E-F-V-T-M-M-T-S-K"} +{"text": "### FUNCTION Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions ### SEQUENCE -M-G-R-R-R-V-K-R-R-I-N-I-P-K-R-Q-S-R-L-E-K-R-F-N-C-P-V-C-N-H-E-N-V-V-Q-C-T-V-K-K-T-L-M-K-G-F-A-N-C-S-V-C-E-A-S-F-A-C-D-A-N-K-L-T-T-G-I-D-V-Y-S-A-W-V-D-E-C-C-K-R"} +{"text": "### FUNCTION May play a role in vesicular transport from endoplasmic reticulum to Golgi ### SEQUENCE -M-K-R-E-V-P-V-S-T-M-S-Y-L-V-C-G-M-I-E-Y-L-M-E-Q-R-S-D-I-E-A-D-L-K-S-I-G-Y-E-V-G-I-K-L-L-E-L-C-N-F-E-R-E-V-R-I-S-T-L-L-Y-R-A-T-F-D-L-L-S-L-V-S-D-S-D-R-R-V-E-K-A-R-D-V-D-R-T-Y-L-L-T-D-S-D-G-L-F-S-R-F-I-S-V-P-D-E-W-N-G-L-S-A-D-S-I-V-C-G-M-I-Q-A-A-L-M-A-S-G-Y-D-S-E-V-T-A-F-P-E-P-S-E-N-L-P-N-R-V-I-F-Q-I-R-I-L-D-L"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-S-G-S-R-F-E-R-E-L-E-F-V-Q-L-L-C-N-P-D-Y-L-R-W-L-T-R-E-G-H-F-E-S-E-E-F-R-S-Y-L-R-Y-L-E-Y-W-R-S-P-E-Y-S-R-F-L-T-Y-P-Q-C-L-A-V-L-E-H-L-N-S-E-N-I-N-D-M-L-S-D-E-N-F-F-L-A-L-G-E-Q-Q-Y-F-I-W-L-N-K-H-K-E-G-W-N-K"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-K-A-V-L-L-A-L-A-L-V-Y-G-S-Q-G-T-E-Y-G-G-G-K-M-T-E-A-D-Y-G-E-M-V-R-R-E-K-C-I-M-F-V-K-R-F-C-P-Y-S-I-R-A-R-E-L-L-H-D-R-G-V-G-C-K-I-I-E-V-D-N-N-L-D-A-Y-S-F-A-K-R-N-H-S-T-F-P-V-F-F-L-D-G-D-L-V-E-G-G-C-E-K-L-L-V-L-S-D-S-N-L-P-P-F-D-K-S-P-L-L-T-Q-N-R-E-P-V-L-L-D"} +{"text": "### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-D-M-F-S-A-P-D-R-I-P-E-Q-I-R-I-F-F-K-T-M-K-Q-V-V-P-A-K-A-V-C-G-S-T-V-L-D-V-A-H-K-N-G-V-D-L-E-G-A-C-E-G-N-L-A-C-S-T-C-H-V-I-L-E-E-P-L-Y-R-K-L-G-E-P-S-D-K-E-Y-D-L-I-D-Q-A-F-G-A-T-G-T-S-R-L-G-C-Q-L-R-V-D-K-S-F-E-N-A-V-F-T-V-P-R-A-T-K-N-M-A-V-D-G-F-K-P-K-P-H"} +{"text": "### FUNCTION The GINS complex plays an essential role in the initiation of DNA replication ### SEQUENCE -M-A-I-S-P-E-E-I-L-H-I-A-Y-E-E-L-V-E-I-E-P-M-T-S-I-P-E-L-R-L-L-E-R-T-Y-P-P-L-M-P-L-D-I-A-R-I-P-L-Y-A-A-L-L-L-K-K-S-N-M-C-K-I-R-L-P-S-Y-L-Q-L-E-S-L-K-M-S-M-D-V-E-I-E-K-A-D-E-Y-S-C-I-H-P-Y-F-F-P-L-A-T-E-L-L-E-N-C-Y-N-V-E-S-I-E-E-S-K-M-I-V-E-K-I-K-E-I-R-L-A-K-T-L-K-G-I-K-C-L-D-G-K-A-L-N-M-N-N-I-T-L-F-E-F-N-E-I-K-E-L-I-L-G-S-A-E-V-G-R-R-I-E-D-L-A-K-D-Q"} +{"text": "### FUNCTION TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation ### SEQUENCE -M-L-K-I-Y-E-D-I-I-N-E-V-I-S-R-L-E-Q-V-E-D-E-V-S-I-G-K-S-A-I-H-E-L-R-N-E-W-R-E-R-L-I-E-Y-T-Q-S-E-W-D-G-E-R-M-R-R-R-D-G-E-Q-G-Y-H-G-Y-E-R-L-S-E-G-P-A-H-A-F-G-G-K-P-T-T-A-K-D-P-G-M-F-E-D-Y-G-S-S-D-V-S-S-G-D-S-E-I-I-G-T-K-G-S-T-G-N-C-M-V-C-L-Y-V-K-V-N-M-S-K-G-K-W-K-C-T-F-K-Q-G-F-I-S-I-G-N-I-D-F-V-F-N-S-A-Q-G-E-L-E-W"} +{"text": "### FUNCTION Acts as a sulfur carrier required for 2-thiolation of mcm that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1 The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates ### SEQUENCE -M-K-F-R-F-N-G-A-S-N-V-E-L-N-N-R-E-I-E-L-T-R-E-E-V-E-G-S-S-I-A-T-V-G-D-A-L-R-Y-L-F-G-K-Y-A-E-T-R-D-S-F-F-D-H-H-G-E-L-V-H-G-T-I-C-I-I-N-K-M-D-W-E-I-L-E-K-E-R-S-P-V-K-H-G-D-H-I-V-L-I-S-T-I-H-G-G"} +{"text": "### FUNCTION May be involved in mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum EGD2 may also be involved in transcription regulation ### SEQUENCE -M-A-R-A-L-T-T-D-E-S-H-I-H-K-T-L-G-A-K-V-G-L-E-E-V-E-A-V-E-R-I-A-I-V-V-K-D-T-R-Y-S-V-E-S-P-V-A-Y-R-I-K-G-T-D-S-I-L-I-F-G-D-L-G-S-P-V-N-L-H-Q-L-K-R-M-Y-E-D-S-I-R-S-S-K-D-Q-E-G-P-G-L-Y-D-E-I-H-S-D-P-Q-E-D-G-V-K-E-A-E-E-I-T-V-D-P-S-D-E-R-L-S-E-E-D-I-K-L-I-S-S-Q-V-K-A-S-R-N-D-I-I-K-A-L-V-E-S-E-Y-D-V-V-D-A-M-M-K-L-T-K"} +{"text": "### FUNCTION Ubiquitin exists either covalently attached to another protein, or free Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked Lys-6-linked may be involved in DNA repair ### SEQUENCE -M-Q-I-F-V-K-T-L-T-G-K-T-I-T-L-E-V-E-P-S-D-S-I-E-N-V-K-A-K-I-Q-D-K-E-G-I-P-P-D-Q-Q-R-L-I-F-A-G-K-Q-L-E-D-G-R-T-L-S-D-Y-N-I-Q-K-E-S-T-L-H-L-V-L-R-L-R-G-G-Y"} +{"text": "### FUNCTION Component of the cytosolic iron-sulfur , probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2 ### SEQUENCE -M-E-D-K-E-E-L-R-K-L-L-R-S-M-M-R-K-S-T-D-P-R-T-K-M-Q-D-E-Y-L-T-D-E-D-K-A-I-Q-R-S-E-R-P-P-A-K-K-R-A-C-K-D-C-T-C-G-L-K-E-E-Q-E-V-R-T-R-S-A-C-G-N-C-Y-K-G-D-A-F-R-C-S-G-C-P-S-L-G-L-P-P-Y-E-P-G-D-V-V-S-F-S-M-D-L-S-N-E-F-Q-G-E-D-A"} +{"text": "### FUNCTION Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome ### SEQUENCE -M-P-K-S-D-T-K-Q-K-K-R-R-S-N-K-N-R-L-R-I-K-R-A-R-L-F-G-P-K-D-I-D-Q-V-K-E-D-I-E-S-Q-K-K-I-E-Y-D-P-E-L-P-G-G-G-H-F-Y-C-C-E-C-D-R-H-F-I-T-E-K-V-L-M-E-H-K-R-S-N-P-H-R-R-R-A-K-E-V-R-E-V-A-H-S-Q-R-D-A-E-W-A-V-G-L-T"} +{"text": "### FUNCTION Promotes the assembly and repair of iron-sulfur clusters by delivering Fe to proteins involved in these pathways ### SEQUENCE -M-L-H-K-Q-T-P-E-D-V-I-T-R-Q-L-Y-H-K-L-A-D-E-T-L-T-D-L-S-E-Q-L-D-K-E-L-D-G-G-Y-A-D-Y-K-D-G-N-L-Q-I-K-I-D-N-V-G-E-Y-M-F-N-K-Q-P-A-S-M-Q-I-W-A-S-S-P-I-T-G-P-R-K-F-D-I-C-R-R-H-E-W-I-D-L-K-S-N-T-S-F-S-R-Y-I-E-E-E-L-R-R-M-R-S-K-M-A-G-K-H-K-K"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-E-E-R-E-E-S-I-S-F-V-D-Q-R-F-L-G-S-K-P-L-D-D-T-N-V-L-E-Y-F-S-G-S-P-F-Y-D-K-S-C-N-N-E-I-L-K-M-Q-T-Q-F-R-G-L-D-Q-K-S-K-L-F-S-M-V-G-I-F-Y-E-V-E-S-S-N-H-E-K-T-L-F-V-I-R-K-A-Y-N-H-G-D-T-A-E-T-L-G-M-Y-Y-I-I-H-G-H-V-Y-A-A-P-T-N-Y-S-I-Y-R-C-R-M-G-D-S-M-W-Q-L-N-S-F-I-D-R-M-M-E-K-R-R-F-N-P-F-S-P-P-K-G-R-R-L-A-K-S-L-E-D-S-K-D-L-D-F-M-M-E-I-F-N-D-F-K-K-E-Q-A-E-S"} +{"text": "### FUNCTION May be a phenoloxidase inhibitor that stabilizes or inhibits venom phenoloxidase while it is stored in the venom sac ### SEQUENCE -M-S-R-Y-A-L-I-V-L-I-V-V-V-V-A-A-N-L-C-E-A-S-D-C-G-P-N-R-V-Y-K-S-C-G-T-G-C-P-E-T-C-E-N-P-D-P-D-C-D-R-A-C-H-Q-G-C-F-C-S-K-G-L-L-Q-D-I-D-G-N-C-I-S-P-D-K-C-P"} +{"text": "### FUNCTION May be a phenoloxidase inhibitor that stabilizes or inhibits venom phenoloxidase while it is stored in the venom sac ### SEQUENCE -M-C-R-Y-A-L-I-V-L-V-V-V-V-V-A-T-N-L-S-E-A-N-I-F-D-V-P-T-C-E-P-N-R-I-Y-K-T-C-G-P-A-C-P-P-T-C-E-D-P-D-P-D-C-N-E-T-P-Q-C-K-A-G-C-F-C-I-P-G-L-I-E-N-M-K-G-G-N-C-I-S-P-S-L-C-P"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-L-K-K-F-L-I-S-S-I-V-K-P-T-F-Q-S-R-I-I-A-S-T-T-L-N-G-G-A-G-R-A-T-F-C-S-V-N-S-I-N-P-N-P-T-A-S-Q-I-K-V-D-Q-E-D-L-E-V-G-E-H-L-V-I-D-D-P-N-Q-Q-H-I-K-S-F-L-N-G-V-E-F-N-G-K-S-V-N-I-Y-R-P-S-R-N-T-M-Q-T-G-T-L-R-T-K-K-W-V-I-E-L-P-F-N-P-K-W-N-D-R-L-M-G-W-W-A-S-K-D-T-L-N-Q-L-N-L-R-F-N-S-E-T-D-A-V-A-Y-C-K-E-I-G-L-N-Y-N-I-V-E-E-D-V-T-L-R-K-K-K-K-Y-G-H-R-F-R-Y-R-G-D-L-V-G-E-K-E-R-E-V-G-I-N"} +{"text": "### FUNCTION Involved in the mitochondrial division probably by regulating membrane fission Loss-of-function leads to apoptosis ### SEQUENCE -M-T-P-V-E-E-I-I-K-K-D-I-F-R-E-T-P-L-R-Y-L-G-Y-A-N-E-V-G-E-A-F-R-S-L-V-K-P-V-V-V-K-F-S-Y-V-V-A-F-G-Y-V-A-A-D-S-I-D-K-G-L-Q-E-Y-I-K-T-H-S-T-S-T-E-K-T-K-K-V-A-I-A-A-V-D-T-V-L-W-Q-T-F-A-S-V-L-I-P-G-F-T-I-N-R-F-C-F-F-S-N-L-L-L-Q-K-S-T-K-L-P-T-N-M-R-K-W-T-V-T-C-L-G-L-A-T-I-P-F-I-V-H-P-I-D-S-F-V-E-E-A-M-D-K-T-A-R-K-I-Y-N-E-P-T-I-S-N-K-E"} +{"text": "### FUNCTION Putative insecticidal toxin ### SEQUENCE -M-A-L-A-L-L-G-L-T-I-K-P-E-H-V-P-E-G-T-G-K-A-V-A-D-V-E-A-L-A-C-D-P-A-Q-C-M-R-S-C-P-F-N-P-F-L-N-Q-Y-G-G-I-C-K-N-G-Q-C-V-C-V-K-P-S"} +{"text": "### FUNCTION Depressant insect toxins cause a transient contraction paralysis followed by a slow flaccid paralysis They bind voltage-independently to sodium channels ### SEQUENCE -M-K-L-F-L-L-L-L-I-S-A-S-M-L-I-D-G-L-V-N-A-D-G-Y-I-R-G-S-N-G-C-K-V-S-C-L-W-G-N-E-G-C-N-K-E-C-G-A-Y-G-A-S-Y-G-Y-C-W-T-W-G-L-A-C-W-C-E-G-L-P-D-D-K-T-W-K-S-E-S-N-T-C-G-G-K-K"} +{"text": "### FUNCTION Ca with the concomitant emission of light ### SEQUENCE -M-A-S-K-Y-A-V-K-L-Q-T-D-F-D-N-P-K-W-I-K-R-H-K-F-M-F-D-Y-L-D-I-N-G-N-G-Q-I-T-L-D-E-I-V-S-K-A-S-D-D-I-C-K-N-L-G-A-T-P-A-Q-T-Q-R-H-Q-D-C-V-E-A-F-F-R-G-C-G-L-E-Y-G-K-E-T-K-F-P-E-F-L-E-G-W-K-N-L-A-N-A-D-L-A-K-W-A-R-N-E-P-T-L-I-R-E-W-G-D-A-V-F-D-I-F-D-K-D-G-S-G-T-I-T-L-D-E-W-K-A-Y-G-R-I-S-G-I-S-P-S-E-E-D-C-E-K-T-F-Q-H-C-D-L-D-N-S-G-E-L-D-V-D-E-M-T-R-Q-H-L-G-F-W-Y-T-L-D-P-E-A-D-G-L-Y-G-N-G-V-P"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-Q-Y-V-D-Q-H-L-V-A-T-Q-C-V-T-M-A-A-I-C-G-L-D-G-S-I-W-A-K-S-N-G-L-E-L-S-Q-D-E-V-A-T-L-A-R-S-F-S-K-D-E-V-L-A-A-N-G-I-R-I-G-G-T-K-Y-I-Y-L-S-G-D-D-K-L-I-R-G-K-K-D-R-Q-G-V-H-I-V-K-T-K-T-A-M-V-M-A-L-Y-A-E-P-I-L-P-E-Q-C-A-V-V-V-E-K-L-G-D-W-L-I-Q-N-D-L"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-V-H-H-I-T-S-N-D-E-L-Q-K-L-L-S-S-T-T-Y-V-V-V-D-F-F-A-D-W-C-P-P-C-K-A-I-A-P-V-Y-E-Q-L-S-T-K-H-S-V-P-D-V-L-A-F-A-K-V-N-V-D-H-V-Q-D-A-A-Q-Q-Y-G-I-T-A-M-P-T-F-M-F-F-K-E-G-K-Q-V-A-V-N-G-Q-A-V-I-K-G-A-D-P-R-T-L-G-A-A-A-E-K-L-G-G-L-A-Q-K-R-V-A-G-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-L-L-S-S-N-E-L-R-K-L-I-Q-A-T-P-H-L-L-E-N-A-V-D-I-E-T-Q-I-Q-P-N-G-L-E-L-T-L-K-E-I-K-T-I-E-G-V-G-A-V-D-F-D-N-S-E-R-K-V-P-D-A-K-P-L-E-F-E-D-D-D-W-I-H-L-P-K-G-I-Y-K-V-I-F-N-E-I-V-N-I-P-M-N-L-A-A-I-A-K-P-R-S-S-L-I-R-C-G-A-T-L-E-T-A-V-W-D-A-G-Y-R-G-R-S-E-S-M-L-V-V-Y-N-S-A-G-F-R-L-K-K-N-A-R-I-M-Q-L-L-F-Y-T-L-N-S-E-V-E-E-G-Y-S-G-V-Y-Q-N-E-N-T-K"} +{"text": "### FUNCTION Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA and pyrophosphate ### SEQUENCE -M-T-P-L-A-R-F-R-K-V-V-V-G-G-T-F-D-R-L-H-L-G-H-Q-R-L-L-S-V-A-L-E-L-G-D-R-V-V-I-G-V-T-T-D-S-F-V-R-E-E-G-K-K-G-V-E-P-F-E-E-R-V-R-A-V-R-R-F-V-E-E-K-G-A-S-D-R-V-E-I-V-P-L-E-D-R-Y-G-T-T-L-E-D-D-E-M-D-A-I-V-V-S-P-E-T-E-P-V-A-L-E-I-N-E-L-R-R-K-R-G-F-P-P-L-S-I-V-V-I-P-F-V-L-D-G-D-G-R-K-I-S-S-S-R-L-R-G-E-V-D-E-G-P-C-R-D-D"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-P-I-T-P-R-N-I-V-R-H-E-L-I-G-L-E-C-R-V-V-K-S-L-G-P-P-Y-E-G-L-E-G-R-I-V-D-E-T-K-N-T-L-V-L-K-T-E-S-G-E-K-V-I-V-K-D-Q-V-L-L-E-L-K-L-P-S-G-E-R-V-R-V-D-G-A-L-L-V-G-R-P-E-E-R-L-S-K-R-I-K-Y-A-E-V-V-R-G-R-F-D-P-E-D-Y-L-D"} +{"text": "### FUNCTION Endonuclease that removes tRNA introns Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp ### SEQUENCE -M-L-C-A-G-N-G-G-K-E-L-P-R-A-K-V-F-E-G-G-S-L-V-S-K-D-Y-E-D-L-K-R-R-Y-F-G-T-E-H-G-N-V-L-F-L-D-P-F-E-T-V-Y-L-T-E-K-G-E-I-D-P-E-T-P-E-G-E-P-M-S-V-E-E-L-L-S-F-F-E-R-R-R-P-G-F-R-A-G-Y-V-V-Y-R-D-L-T-E-R-G-Y-V-V-K-S-G-F-K-Y-G-G-R-F-R-V-Y-E-E-D-P-D-R-E-H-S-K-Y-V-V-R-V-V-E-P-D-T-E-L-S-T-R-D-V-L-R-A-T-R-L-A-H-S-V-R-K-D-F-V-L-A-V-V-E-D-V-E-E-P-R-I-E-Y-V-M-W-R-W-K-R-L"} +{"text": "### FUNCTION RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus ### SEQUENCE -M-I-R-F-I-L-D-T-S-I-F-V-N-P-D-V-R-K-K-F-G-N-T-P-T-E-A-M-K-T-F-L-K-Y-A-E-K-L-F-G-K-V-E-F-Y-M-P-P-G-I-Y-K-E-V-K-N-F-L-E-D-I-P-P-E-M-E-L-Y-I-I-K-K-P-P-N-V-H-D-I-K-I-P-A-F-V-V-Y-E-L-I-E-D-I-R-R-R-V-D-K-G-L-R-V-A-E-K-A-V-R-E-S-V-I-D-T-N-N-V-D-K-I-I-Q-K-L-R-R-N-Y-R-K-A-L-R-E-G-I-V-D-S-T-E-D-F-E-L-I-L-L-A-K-E-I-D-G-I-I-V-S-A-D-V-G-I-L-T-W-A-E-K-M-G-I-K-W-V-D-A-F-K-F-K-E-L-L-D-E-L-V-E-K-V-E-S-E-K-E-R-K"} +{"text": "### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-K-K-F-R-F-F-V-S-G-M-P-G-V-G-K-T-T-L-A-K-R-I-A-D-E-I-K-R-E-G-F-K-V-G-G-I-I-T-Q-E-I-R-S-G-A-R-R-S-G-F-R-V-I-A-L-D-T-G-E-I-G-R-L-A-Y-V-G-Q-G-Y-P-R-L-G-R-Y-V-I-D-V-E-S-F-E-K-V-A-I-P-A-I-S-R-A-L-R-E-G-D-L-I-V-I-D-E-I-G-P-M-E-F-K-S-N-E-F-L-K-A-L-G-L-V-L-R-S-E-K-P-L-L-A-T-V-H-R-R-F-V-E-R-Y-R-P-L-G-E-Y-Y-W-L-T-P-E-N-R-E-A-V-F-S-E-I-L-V-K-I-K-E-L-L-R-E-N-E-N-A-G-N-K-A-Q-D"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-K-E-K-R-D-L-K-I-Q-A-I-E-N-G-T-V-I-D-H-I-T-A-G-Q-A-L-N-V-L-R-I-L-R-I-S-S-A-F-R-A-T-V-S-F-V-M-N-A-P-G-A-R-G-K-K-D-V-V-K-I-E-G-K-E-L-S-V-E-E-L-N-R-I-A-L-I-S-P-K-A-T-I-N-I-I-R-D-F-E-V-V-Q-K-N-K-V-V-L-P-S-Y-V-E-G-V-V-R-C-M-N-S-N-C-I-S-N-S-S-E-P-I-K-S-K-F-S-V-L-R-T-E-E-E-G-V-S-L-H-C-L-Y-C-E-H-V-I-S-E-E-I-A-E-N-L-L"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-S-E-S-S-I-K-I-E-N-V-V-A-S-T-K-L-A-E-E-F-D-L-T-V-I-E-S-E-F-E-G-A-E-Y-N-K-Q-K-F-P-G-L-V-Y-R-V-S-D-P-K-A-A-F-L-V-F-T-S-G-K-V-V-C-T-G-A-K-N-V-A-D-V-H-T-V-I-G-N-M-A-K-K-L-N-S-I-G-I-K-T-M-E-N-P-Q-I-T-V-Q-N-I-V-A-S-A-D-L-H-T-I-L-N-L-N-A-I-A-I-G-L-G-L-E-N-I-E-Y-E-P-E-Q-F-P-G-L-V-Y-R-I-D-E-P-K-V-V-V-L-I-F-S-S-G-K-L-V-V-T-G-G-K-S-P-E-D-C-E-R-G-V-E-V-V-R-Q-Q-L-D-N-M-G-L-L"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-T-S-I-V-E-A-L-V-P-G-G-K-A-N-P-G-P-P-L-G-P-A-L-G-P-L-G-V-N-I-K-E-V-V-E-K-I-N-E-K-T-R-D-Y-N-G-M-Q-V-P-V-K-V-I-V-D-D-K-K-N-V-E-I-E-V-G-T-P-P-T-A-S-L-V-M-K-E-L-G-I-Q-K-G-S-G-N-A-G-S-E-V-V-G-N-L-T-I-S-Q-V-A-K-V-A-R-M-K-K-E-D-V-L-S-Y-D-L-K-A-A-M-K-E-V-M-G-S-C-V-P-M-G-V-N-V-E-G-M-K-A-K-D-C-Q-K-A-L-D-E-G-K-F-D-D-L-L-A-G-E-A-W"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-V-E-S-T-F-E-P-N-I-T-T-K-S-V-G-Q-A-I-R-A-H-L-R-V-L-K-L-T-K-K-P-S-R-E-E-F-L-T-I-A-K-V-A-G-A-G-I-L-A-V-G-A-I-G-F-I-I-Y-V-L-L-T-M-L-P-Q-W-V-S-Q"} +{"text": "### FUNCTION Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7 ### SEQUENCE -M-S-E-I-V-S-V-S-G-G-P-T-K-P-E-I-I-A-V-S-L-S-K-L-G-L-Q-D-G-D-R-F-A-D-V-G-C-G-T-G-S-V-S-I-E-A-A-R-I-A-R-N-L-T-I-Y-A-I-D-A-R-K-E-A-L-L-A-T-E-A-N-F-K-S-F-G-I-E-N-A-R-V-L-A-G-E-A-S-E-L-L-G-S-G-G-S-I-D-S-I-D-C-A-F-V-G-G-T-K-N-I-D-A-I-L-E-K-L-V-E-K-K-T-R-S-I-V-V-N-A-V-R-I-E-T-V-V-R-T-I-E-A-M-K-K-L-G-I-F-D-E-V-V-H-I-S-V-S-R-S-A-P-I-A-G-E-T-M-F-K-P-E-N-P-V-Y-I-V-V-G-K-K-Q-A"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-E-L-A-V-I-G-K-S-E-F-V-T-G-F-R-L-A-G-I-R-K-V-Y-E-I-V-D-V-P-S-S-E-S-A-V-K-S-V-L-E-D-K-S-I-G-I-L-V-M-H-N-D-D-I-S-N-L-P-E-I-L-R-R-N-L-N-E-S-V-Q-P-T-V-V-A-L-G-G-T-G-E-G-S-M-S-L-R-D-K-I-K-Q-A-V-G-V-D-L-W-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-G-L-E-I-V-I-K-D-I-Q-E-G-A-R-A-E-V-S-R-I-N-T-E-A-D-A-K-A-S-E-I-T-N-E-A-K-E-V-Q-K-K-M-L-G-D-S-L-A-K-V-E-E-D-L-Q-K-L-H-Q-Q-V-I-S-S-A-N-L-E-V-K-R-I-T-L-N-K-R-K-E-L-L-D-N-V-Y-S-Q-T-V-E-S-I-K-S-M-P-A-S-K-N-E-K-L-L-K-H-I-I-D-K-Y-E-A-S-G-D-K-I-Y-S-S-K-A-S-E-E-T-V-R-K-L-S-S-L-T-Y-A-G-N-I-D-C-I-G-G-V-V-L-E-N-E-D-G-T-V-R-L-D-Y-T-Y-D-S-I-L-K-N-V-Y-E-R-S-L-K-Q-I-S-D-I-L-Y-G"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-A-E-V-S-E-E-I-R-N-L-A-A-R-H-Q-E-L-Q-R-Q-A-E-A-L-R-Q-E-M-G-M-I-Q-T-S-I-S-S-C-D-Q-T-I-V-T-I-N-E-L-K-A-A-S-E-A-G-K-P-A-E-T-M-V-P-V-G-F-G-S-Y-V-Y-A-E-V-K-N-P-D-R-I-I-V-N-L-G-A-E-F-S-A-E-E-T-A-E-E-A-I-E-T-L-N-R-R-K-E-Q-L-T-K-I-L-E-Q-M-N-A-S-L-T-R-L-T-Q-G-M-Q-T-L-E-A-E-A-A-K-L-Q-P-G-Q-A"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-G-T-G-G-F-I-G-A-S-L-R-Y-T-I-S-S-R-V-P-K-I-Q-N-I-P-A-G-T-L-T-V-N-L-L-G-S-I-V-L-A-L-L-T-F-S-S-E-P-E-S-V-V-Y-L-V-N-I-G-M-L-G-S-F-T-T-F-S-T-F-A-Y-E-T-F-R-L-L-E-D-G-Q-N-I-S-F-F-L-N-I-F-L-N-V-M-L-C-L-L-G-V-S-I-A-Y-L-A-L-M-L"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-P-S-Q-D-K-E-I-D-K-I-F-L-I-G-A-G-G-F-L-G-A-V-C-R-F-L-L-C-E-L-V-E-G-Q-L-G-I-L-S-V-N-V-I-G-S-F-M-L-G-M-I-M-Y-D-T-E-Y-L-G-F-I-G-P-K-G-K-I-A-F-G-T-G-F-M-G-A-F-T-T-F-S-T-F-A-V-Q-S-F-S-L-P-F-I-P-A-L-G-N-I-S-A-N-I-F-L-T-L-T-G-V-F-F-G-R-S-V-I-K-A-L-S-S-R-E-I"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-E-T-E-L-M-R-I-G-V-S-L-P-D-T-L-L-S-K-F-D-E-I-I-E-K-R-G-Y-S-S-R-S-E-G-I-R-D-A-I-R-S-Y-I-S-Y-Y-E-W-M-G-D-I-K-G-H-R-V-G-T-V-A-V-I-Y-D-H-T-K-R-G-L-S-N-A-L-A-D-I-Q-H-H-Y-S-H-L-I-K-S-S-V-H-I-H-L-D-H-D-N-C-F-E-V-I-V-L-D-G-D-G-E-E-I-K-E-L-A-E-A-I-M-A-L-K-G-V-K-F-S-K-L-T-T-V-A-S-N-E-K-I"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Y-T-I-L-L-I-G-I-G-G-F-I-G-A-V-L-R-Y-S-L-S-G-W-V-Q-N-S-F-V-N-F-P-L-G-T-L-V-V-N-I-V-G-S-F-F-L-G-L-V-M-Y-L-S-E-Y-Q-G-L-F-S-E-E-T-R-I-L-L-T-I-G-L-L-G-A-F-T-T-L-S-T-F-S-Y-E-S-F-R-L-L-E-S-S-K-L-M-Q-L-T-M-N-I-V-A-T-V-L-F-S-I-F-A-V-Y-L-G-K-I-S-A-L-N-L-A-A-Y-L-R-G-I-K"} +{"text": "### FUNCTION Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein and RNA polymerase recruitment Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes ### SEQUENCE -M-N-T-L-V-D-L-N-D-K-V-I-R-G-Y-L-I-S-L-V-G-E-E-G-L-R-M-I-E-E-M-P-E-G-E-V-T-D-E-E-I-A-A-K-T-G-V-L-L-N-T-V-R-R-T-L-F-I-L-Y-E-N-K-F-A-I-C-R-R-E-R-D-S-N-S-G-W-L-T-Y-L-W-H-L-D-F-S-D-V-E-H-Q-L-M-R-E-K-K-K-L-L-R-N-L-K-T-R-L-E-F-E-E-N-N-V-F-Y-V-C-P-Q-G-C-V-R-L-L-F-D-E-A-T-E-T-E-F-L-C-P-M-C-G-E-D-L-V-Y-Y-D-N-S-R-F-V-S-A-L-K-K-R-V-D-A-L-S-S-V"} +{"text": "### FUNCTION Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase The precise role of the epsilon subunit is unclear ### SEQUENCE -M-V-D-T-T-K-N-T-K-L-F-T-S-Y-G-V-T-T-S-K-T-T-T-P-E-I-A-A-K-L-I-S-K-A-K-R-P-L-L-V-V-G-T-K-V-L-D-P-E-L-L-D-R-A-V-K-I-A-Q-K-A-N-I-P-I-A-A-T-G-S-S-M-P-G-F-V-G-K-D-V-D-A-K-Y-I-N-L-H-Q-L-G-F-Y-V-T-D-P-N-W-P-G-L-D-G-N-G-T-Y-D-T-L-I-V-L-G-H-I-K-Y-Y-I-N-Q-V-L-S-G-T-K-N-F-S-T-V-K-A-I-A-I-E-R-N-Y-I-Q-N-A-T-M-S-F-G-N-L-S-K-A-D-H-Y-A-A-L-D-E-L-I-D-A-L"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-T-S-E-L-P-P-Q-I-Q-N-Q-I-A-Q-L-Q-Q-V-Q-Q-Q-V-Q-A-L-A-M-Q-K-S-Q-I-E-A-M-Q-K-E-S-K-M-A-L-E-E-L-E-K-L-A-D-D-A-V-V-Y-R-N-V-G-E-L-V-I-K-T-S-K-E-E-S-V-S-K-L-K-D-R-E-E-T-L-S-L-R-L-Q-S-I-S-R-Q-E-E-R-L-T-T-R-F-K-Q-L-Q-E-Q-I-Q-Q-A-L-G-P-K-A-Q"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-S-F-L-T-N-F-L-L-G-L-G-L-A-M-D-A-F-A-V-S-M-S-S-G-T-T-I-R-P-F-R-V-S-D-A-L-K-L-A-V-F-F-G-S-F-Q-A-M-M-P-V-L-G-W-I-G-G-S-T-V-S-S-F-V-S-D-Y-A-P-W-I-A-F-L-L-L-A-F-I-G-C-K-M-I-Y-E-A-L-Y-G-D-Q-D-G-K-V-N-S-L-N-Y-S-V-L-F-L-L-A-V-A-T-S-I-D-A-L-A-V-G-M-S-F-A-F-L-G-T-P-I-L-E-P-V-I-I-I-G-C-V-T-F-V-M-S-F-C-G-A-I-L-G-Y-R-L-G-H-F-F-E-H-E-V-E-I-L-G-G-L-I-L-I-G-L-G-G-K-I-L-A-E-H-M-L-W-I"} +{"text": "### FUNCTION Broad-specificity nucleoside monophosphate kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-L-I-G-L-T-G-T-P-G-T-G-K-T-S-V-S-K-L-L-E-K-K-R-Q-W-K-I-I-H-L-N-E-L-I-K-E-E-H-L-Y-T-E-V-D-E-K-R-D-S-V-V-A-D-M-E-L-V-R-S-R-L-P-E-L-I-N-E-M-E-K-E-P-A-N-K-V-V-I-L-E-S-H-L-A-H-Y-I-T-D-I-V-I-V-L-R-A-Y-P-P-E-L-K-K-R-L-E-K-R-G-Y-S-E-E-K-V-N-E-N-A-E-A-E-S-I-D-L-I-L-A-E-A-F-E-W-C-D-K-V-F-E-I-N-T-T-G-R-T-A-E-E-T-A-G-D-V-E-K-I-I-D-S-L-L-S-G-K-E-E-Q-L-Q-E-Y-G-P-G-S-L-D-W-I-D-S-V-P"} +{"text": "### FUNCTION Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A ### SEQUENCE -M-S-V-H-I-E-L-P-T-E-L-R-P-L-M-K-R-P-L-G-T-L-Y-R-G-K-G-R-D-T-V-E-K-F-V-G-E-L-A-S-P-T-K-L-I-S-V-G-D-V-T-T-F-H-L-L-E-A-G-I-I-P-D-I-C-I-V-D-N-R-T-K-R-K-P-V-S-R-D-V-S-D-R-N-R-D-K-V-Y-E-E-V-S-V-D-N-P-A-G-I-I-T-D-E-L-I-K-T-L-C-E-A-F-D-S-E-K-L-L-R-I-F-V-R-G-E-E-D-L-A-T-L-P-V-I-L-M-A-P-L-G-S-V-V-L-Y-G-Q-P-D-E-G-V-V-F-V-R-V-T-E-E-K-K-E-E-I-R-V-L-F-E-K-L-I-S-K-N-Q-N-T-E-L-D-K-I-R-R-I-L-D-G-H-K-D-P"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-Y-V-V-I-V-Y-D-V-G-V-E-R-V-N-K-V-R-S-F-L-R-E-Y-M-N-W-V-Q-N-S-V-F-E-G-E-L-T-K-A-E-F-L-K-I-K-S-R-L-K-E-L-I-Q-E-S-S-D-H-I-I-F-Y-S-S-R-D-R-K-Y-L-G-I-E-D-L-G-T-P-K-A-D-T-S-N-I-I"} +{"text": "### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-L-R-I-A-V-T-G-S-P-G-V-G-K-S-T-V-V-A-K-T-A-E-K-L-A-E-K-P-G-F-K-I-G-G-I-R-T-A-E-I-R-K-E-G-H-R-E-G-F-S-I-R-D-L-A-T-G-K-T-G-I-L-S-H-V-K-G-S-G-P-R-L-G-K-Y-H-V-N-L-D-D-L-E-R-I-G-A-N-A-V-R-N-A-L-A-C-D-L-V-V-I-D-E-I-G-P-M-E-L-I-S-Q-S-F-V-S-A-V-E-E-V-L-E-S-D-K-P-V-L-A-V-L-H-H-S-S-R-H-P-L-A-Q-R-F-R-K-G-F-E-V-L-T-V-D-K-G-N-R-D-E-L-P-E-K-I-T-N-R-F-L-R-K-L-G"} +{"text": "### FUNCTION Catalyzes the formation of CDP-2,3-bis- and CTP This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-L-P-A-Y-L-S-N-P-F-A-A-V-F-G-G-G-K-P-I-D-G-G-R-T-Y-K-D-G-R-R-I-L-G-D-G-K-T-Y-R-G-L-F-S-G-I-F-C-G-F-L-A-G-C-I-E-I-W-L-S-M-R-G-F-E-I-M-G-I-K-M-P-T-F-G-P-N-Y-A-S-A-L-I-V-V-L-A-L-P-S-G-A-L-F-G-D-M-F-K-S-F-F-K-R-R-M-G-L-K-R-G-A-S-L-P-L-V-D-Q-L-D-F-V-V-G-A-W-F-F-T-Y-L-A-A-P-E-W-F-V-S-N-F-T-T-G-I-A-L-T-V-L-I-M-T-P-L-L-H-L-T-T-N-I-I-G-Y-F-I-G-V-K-K-E-P-W"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-E-Y-K-Q-C-I-V-T-R-D-D-L-K-L-S-K-G-K-F-A-V-Q-V-A-H-A-A-L-S-A-A-E-W-A-S-K-S-D-L-E-K-W-K-E-G-G-Q-K-K-I-V-L-R-V-P-T-I-K-D-L-Y-E-L-K-E-K-A-R-R-E-G-L-P-T-A-L-I-Q-D-A-G-L-T-E-I-P-A-G-T-V-T-V-L-G-I-G-P-A-K-E-E-V-I-D-K-V-T-R-D-L-K-L-V"} +{"text": "### FUNCTION Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs ### SEQUENCE -M-K-R-I-V-L-L-R-L-G-H-R-P-E-R-D-K-R-I-T-T-H-V-G-L-T-A-R-M-L-G-A-E-G-M-L-L-A-S-D-D-Q-G-I-V-H-S-L-E-D-V-V-R-R-W-G-G-D-F-Y-I-K-N-N-V-N-F-K-Q-E-I-R-A-W-K-E-E-G-G-K-V-C-H-L-S-M-Y-G-V-N-L-P-D-V-T-G-E-L-K-K-C-K-K-L-M-I-V-V-G-A-E-K-V-P-P-E-I-Y-Q-L-A-N-W-N-V-A-V-G-S-Q-P-H-S-E-V-A-A-V-A-I-T-M-D-R-I-A-E-G-E-P-L-E-K-E-F-P-G-A-E-L-T-I-V-P-A-E-R-G-K-H-V-I-E-N-I-R-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-S-K-G-T-S-S-M-G-K-R-Q-K-R-T-H-A-K-C-R-R-C-G-S-V-S-F-N-V-H-T-K-Q-C-T-S-C-G-F-G-K-T-S-R-M-R-T-Y-K-W-Q-A-K-C-K-Y"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-E-K-K-L-M-R-I-G-V-S-L-P-G-E-L-L-D-K-F-D-K-T-L-M-K-R-G-Y-S-S-R-S-E-G-I-R-D-A-I-R-T-Y-N-Q-H-Y-E-W-M-Q-Q-I-K-G-A-R-A-A-T-I-S-L-V-Y-D-C-S-K-K-G-I-T-S-T-L-A-K-I-Q-H-E-Y-I-D-L-I-T-S-S-V-H-F-H-I-E-E-D-F-C-F-E-T-I-I-L-E-G-E-G-E-K-I-V-E-L-A-E-K-I-L-S-L-K-G-V-K-H-S-R-L-T-T-M-P-E-V-K-T-E"} +{"text": "### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate forming two phosphate ions ### SEQUENCE -M-L-D-M-T-E-R-Q-V-E-S-V-L-I-E-I-P-K-G-S-R-N-K-Y-E-Y-D-K-E-K-K-V-I-K-F-D-R-M-L-F-S-S-M-V-Y-P-C-D-Y-G-F-F-P-D-T-L-A-L-D-G-D-P-L-D-A-L-V-L-T-W-E-P-T-F-P-G-C-V-I-D-V-H-P-V-A-L-L-D-M-K-D-D-K-G-R-D-E-K-I-L-C-V-P-E-T-D-P-L-W-N-Y-I-E-T-L-E-Q-V-P-P-H-L-L-K-E-I-V-H-F-F-E-T-Y-K-N-L-E-G-K-H-V-I-V-I-G-W-E-G-L-D-A-A-V-D-M-L-R-E-A-K-S-R-Y-L-E-K-N-K"} +{"text": "### FUNCTION Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in Mjannaschii 16S rRNA It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3- ### SEQUENCE -M-M-N-P-T-N-S-R-D-V-P-L-Y-I-Y-H-A-G-Q-C-D-P-K-K-C-T-G-R-K-M-A-R-F-E-L-A-R-L-Y-D-K-I-S-R-L-P-R-S-A-I-L-L-D-P-M-A-E-K-A-L-S-P-A-D-D-P-K-K-G-I-I-V-L-D-C-S-W-E-E-V-E-R-V-F-P-E-L-E-K-L-N-L-E-H-R-A-L-P-Y-M-L-A-G-N-P-V-N-F-G-R-P-F-K-L-N-S-A-E-A-F-A-A-A-L-Y-I-L-G-Y-K-E-Q-A-E-K-V-M-S-K-F-N-W-G-H-S-F-L-E-L-N-R-E-P-L-D-E-Y-A-T-A-K-N-S-S-E-I-V-E-I-Q-S-H-Y-I"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-I-S-L-G-F-V-I-A-E-F-N-R-D-L-T-Y-Q-M-E-L-L-G-R-E-H-A-E-F-L-G-A-T-V-K-E-T-I-L-V-P-G-V-F-D-M-P-L-A-I-K-K-L-C-Q-R-E-D-I-D-A-V-V-T-I-G-S-V-I-E-G-E-T-D-H-D-Q-V-V-M-Q-H-A-A-R-K-I-M-D-L-S-L-E-F-N-K-P-V-T-L-G-I-P-G-P-G-M-T-R-M-A-A-H-E-R-V-D-Y-A-K-R-A-V-E-A-A-V-K-L-V-R-R-L"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-K-R-L-L-P-S-L-R-T-K-K-R-Y-L-A-F-E-L-I-S-E-E-P-A-G-R-G-D-I-V-K-E-V-I-S-S-A-S-S-L-L-G-D-I-T-T-S-D-C-D-I-R-V-L-G-F-E-A-G-K-G-I-I-Q-C-S-H-T-R-V-K-E-T-R-A-A-L-A-T-L-T-R-V-N-G-K-R-A-T-L-H-V-L-G-A-S-G-T-V-K-K-A-T-E-K-F-L-K-D-Y-T-V-F-E-P-E-I-H-E-K-R-D-S-R-K-T-P-G-K-V-D"} +{"text": "### FUNCTION Ferredoxin that is the specific electron donor for the geranylgeranyl reductase GGR involved in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-V-W-H-Y-T-N-D-V-A-L-Y-C-R-A-F-R-S-M-P-H-C-L-R-E-R-Q-Y-F-M-V-K-D-H-D-L-L-L-K-L-T-G-E-L-V-S-V-N-I-N-R-Y-K-C-G-Y-C-G-A-C-V-G-V-C-P-K-G-A-L-E-L-V-E-T-W-I-E-V-D-E-S-T-C-I-K-C-G-I-C-D-R-I-C-P-V-G-A-I-E-V-M-K"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-G-D-V-A-A-K-I-K-I-M-P-E-S-I-E-T-D-L-A-E-L-K-E-K-I-K-A-V-I-P-A-K-A-D-L-H-G-D-I-V-E-E-P-I-A-F-G-L-K-A-L-I-V-T-L-I-V-N-D-E-E-G-G-T-E-P-A-E-E-A-F-A-K-V-S-G-V-E-N-V-Q-V-L-E-A-Y-R-I"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-E-T-E-L-M-R-I-G-I-S-L-P-D-I-L-L-G-E-F-D-E-I-I-G-K-R-G-Y-S-S-R-S-E-G-I-R-D-A-I-R-S-Y-I-S-Y-Y-E-W-M-N-D-I-K-G-H-R-V-G-T-I-A-F-V-Y-D-H-T-K-R-G-L-S-N-S-L-T-D-I-Q-H-H-Y-S-H-L-I-K-S-S-I-H-V-H-L-D-H-K-E-C-F-E-V-V-V-L-N-G-D-G-K-E-I-A-E-L-S-E-T-M-M-V-L-K-G-V-K-F-S-K-L-T-T-V-A-S-N-E-N-I"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-I-R-K-R-Q-S-G-S-N-K-S-V-S-S-G-N-N-Q-E-V-T-R-V-R-T-P-R-K-D-R-N-E-V-L-A-T-V-A-S-L-L-G-S-K-R-V-T-L-Q-C-M-D-G-V-V-R-M-G-R-I-P-G-S-K-N-K-K-M-W-V-R-E-G-D-V-V-I-A-N-P-W-E-I-Q-D-S-K-A-D-V-I-W-K-Y-T-K-P-Q-V-D-W-L-E-R-K-G-Y-L-N"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-R-K-R-R-E-G-S-A-A-P-S-T-Q-E-V-T-R-V-R-T-P-R-K-E-N-H-E-V-L-A-T-V-G-S-L-L-G-S-K-R-V-N-L-Q-C-M-D-G-V-V-R-M-G-R-I-P-G-S-K-N-K-K-M-W-I-R-E-G-D-V-V-I-V-T-P-W-E-I-Q-D-T-K-A-D-V-I-W-K-Y-T-R-P-Q-I-E-W-L-E-R-K-G-Y-L-K"} +{"text": "### FUNCTION Probable toxic component of a putative type VII toxin-antitoxin system, probably an RNase Probably neutralized by cognate antitoxin MA_1295 Neutralization may be due to AMPylation by MA_1295 ### SEQUENCE -M-K-K-D-D-R-V-Y-L-N-H-I-L-Q-S-V-S-L-I-E-K-Y-T-E-D-L-T-E-E-E-F-L-S-N-S-L-F-Q-D-A-T-I-R-Q-I-Q-I-I-G-E-A-T-K-N-L-S-K-S-L-R-D-K-Y-P-Q-V-H-W-R-G-I-A-G-M-R-D-K-L-I-H-D-Y-F-G-V-D-I-N-A-V-W-D-T-I-K-E-D-I-P-A-L-K-K-I-V-L-E-I-I-Q-D-L-N-G-N-P"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-A-K-G-K-Y-A-A-N-I-L-K-Q-T-R-K-D-A-R-W-K-D-T-Y-Y-G-R-R-V-L-G-L-N-V-K-A-D-P-L-G-G-A-P-Q-G-R-G-I-V-L-E-K-V-G-V-E-A-K-Q-P-N-S-A-I-R-K-C-V-R-V-Q-L-I-K-N-G-R-Q-V-T-A-F-C-P-G-D-G-A-V-N-F-I-D-E-H-D-E-V-T-V-E-K-I-G-G-R-M-G-G-A-M-G-D-I-P-G-V-R-F-K-V-I-A-V-N-N-V-S-L-N-Q-L-V-I-G-R-M-E-K-P-R-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center ### SEQUENCE -M-I-F-L-Y-K-I-F-G-K-W-D-P-T-E-V-E-V-K-D-L-G-I-K-R-Y-V-S-L-T-P-V-I-V-P-H-S-S-G-K-H-A-R-Q-Q-F-N-K-S-E-I-S-I-V-E-R-L-A-N-N-L-M-R-T-E-T-N-T-G-K-K-Q-V-T-L-R-A-V-E-E-A-F-D-I-V-N-K-K-T-K-Q-N-P-I-Q-V-L-V-D-A-I-A-N-A-G-P-R-E-E-V-V-R-L-K-Y-G-G-I-S-V-P-K-A-V-D-T-A-P-Q-R-R-V-D-T-A-L-R-Y-I-S-M-G-T-N-A-A-A-F-K-S-K-R-S-V-A-E-C-L-A-T-E-L-I-G-A-A-N-R-D-T-K-S-F-S-I-N-R-K-D-A-K-E-R-V-A-K-A-A-R"} +{"text": "### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-I-F-V-E-K-S-F-T-H-I-E-A-D-R-A-R-M-V-D-I-S-E-K-N-N-V-L-R-M-A-R-A-A-G-E-I-V-L-S-A-E-T-M-E-K-I-R-T-G-T-V-E-K-G-N-V-F-A-T-A-R-V-A-A-V-L-A-V-K-K-T-P-E-T-I-P-M-C-H-Q-I-P-I-T-G-I-D-V-D-L-E-I-G-K-D-S-V-S-A-V-V-E-V-R-T-V-G-K-T-G-V-E-M-E-A-L-T-G-V-S-V-A-L-L-T-V-W-D-M-V-K-S-A-E-K-D-E-T-G-N-Y-P-H-T-L-I-R-N-I-R-V-L-E-K-L-K-G"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-Y-S-I-A-C-E-I-F-E-Q-V-I-E-T-A-K-V-H-G-A-L-E-V-R-H-V-T-L-E-M-G-R-L-S-H-T-N-P-E-Q-L-S-F-C-F-K-A-I-A-E-G-S-I-A-E-N-A-E-F-I-V-E-T-I-P-P-S-L-E-C-E-C-G-Y-T-G-T-V-D-E-T-Q-I-G-K-N-D-E-L-Q-S-E-L-L-E-Y-I-A-A-L-E-C-P-V-C-G-K-N-A-R-I-I-G-G-R-E-L-I-V-K-S-I-E-I-E-T-E-V-E-Q"} +{"text": "### FUNCTION Located on the platform of the 30S subunit ### SEQUENCE -M-A-D-M-K-W-A-V-A-H-I-K-S-S-F-N-N-T-I-I-T-V-T-D-I-T-G-A-E-T-I-A-K-S-S-G-G-M-V-V-K-A-A-R-D-E-S-S-P-Y-T-A-M-Q-M-A-G-Q-L-A-D-Q-L-K-D-K-G-I-N-G-I-H-I-R-V-R-A-P-G-G-N-K-Q-R-S-P-G-P-G-A-Q-A-A-I-R-A-F-A-R-A-G-I-R-I-G-R-I-E-D-V-T-P-V-P-H-D-G-T-R-P-K-G-G-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-L-Y-A-L-Q-W-R-K-Y-M-V-E-E-N-N-N-E-E-L-R-H-L-V-R-I-M-N-T-D-L-Q-G-A-K-P-V-Q-Y-A-L-T-G-L-P-G-V-G-R-R-T-A-K-L-I-A-K-G-A-G-V-D-P-S-A-I-L-G-Y-L-P-E-E-E-V-A-K-L-D-T-A-I-G-K-F-E-D-I-V-P-S-W-M-L-N-R-Q-K-D-L-A-T-G-Q-D-K-H-L-L-G-T-D-I-L-L-T-F-R-E-D-I-N-N-L-K-K-V-R-A-Y-R-G-L-R-H-E-R-G-L-K-V-R-G-Q-R-T-K-S-T-G-R-R-G-S-T-V-G-V-S-R-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-D-T-K-K-F-R-G-S-R-T-C-G-G-G-T-H-K-N-R-R-G-A-G-N-R-G-G-R-G-K-A-G-G-C-K-H-H-F-V-R-A-M-M-R-G-Y-S-Y-G-K-H-G-F-K-R-P-D-E-V-S-R-D-V-S-I-V-N-V-G-E-L-D-E-L-A-S-Y-L-V-E-E-G-L-A-E-V-K-D-G-A-Y-H-I-N-L-E-N-L-G-I-E-K-V-L-G-S-G-R-V-T-K-N-L-V-V-T-S-E-E-F-S-A-S-A-R-E-K-I-E-N-A-G-G-S-C-I-D-A-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-T-G-P-R-Y-K-V-P-F-R-R-R-R-E-G-R-T-N-Y-H-L-R-L-K-L-L-L-S-R-Q-D-R-V-V-V-R-K-S-S-R-N-V-Q-I-Q-L-I-A-P-T-P-D-G-D-I-T-Y-S-S-A-V-S-N-E-L-A-K-Y-G-Y-T-G-A-T-G-N-T-T-A-A-Y-L-T-G-L-L-F-G-L-K-S-L-Q-K-G-Y-E-G-G-I-L-D-I-G-L-Q-A-S-S-A-G-S-R-V-Y-A-A-L-K-G-V-V-D-S-G-F-E-I-P-C-S-P-E-V-F-P-P-D-E-R-I-R-G-E-H-I-A-G-Y-R-E-E-S-S-D-L-P-E-Q-F-E-A-T-K-E-K-I-F-A-E-F-S"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-V-K-E-I-A-R-T-I-E-I-P-E-G-V-S-V-S-L-A-Q-D-V-F-T-A-T-G-P-K-G-T-V-E-R-K-L-W-Y-P-G-I-M-I-D-V-K-D-G-E-V-V-V-D-A-E-Y-A-R-K-E-Q-K-A-M-V-G-T-F-A-S-H-I-R-N-L-V-K-G-V-N-E-G-F-E-C-K-M-S-I-V-Y-A-H-F-P-M-Q-V-K-V-D-G-K-T-L-I-I-G-N-F-L-G-E-K-K-P-R-F-A-K-I-I-G-E-T-K-V-K-V-S-G-N-D-V-T-I-T-G-I-N-K-E-D-V-G-Q-T-A-A-N-I-E-Q-K-T-K-I-K-R-F-D-P-R-I-F-Q-D-G-I-Y-I-V-Q-K-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-L-L-D-P-L-A-N-A-L-S-T-I-K-N-A-E-A-I-G-K-S-S-C-V-V-R-P-A-S-K-N-I-G-N-V-L-K-V-M-Q-D-L-G-Y-I-G-D-F-E-F-I-D-D-G-K-A-G-I-Y-S-V-T-L-V-G-R-I-N-K-C-G-A-I-K-P-R-Y-S-V-G-T-A-S-F-E-R-W-E-K-Q-F-L-P-A-K-N-F-G-A-L-I-V-T-T-S-S-G-V-M-S-Q-Y-E-A-R-D-K-K-I-G-G-Q-L-L-A-Y-V-Y"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-T-E-T-I-K-K-S-G-R-G-V-N-E-C-K-R-C-G-R-K-Q-G-L-V-R-K-Y-D-I-Y-L-C-R-H-C-F-R-E-I-A-H-E-M-G-F-E-K-Y-S"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-R-T-P-I-V-E-K-V-I-V-H-M-G-V-G-E-S-G-Q-H-L-V-N-A-E-D-I-L-R-N-I-T-G-Q-E-V-V-R-C-F-A-K-R-T-L-P-A-F-S-I-K-K-N-E-P-I-G-C-K-V-T-L-R-G-Q-K-A-Q-E-F-L-E-T-A-L-G-I-V-E-K-T-L-N-R-S-Q-F-D-S-F-G-N-V-S-F-G-I-E-E-H-T-D-F-P-G-M-R-Y-D-P-N-I-G-V-F-G-M-D-V-T-V-V-L-K-R-P-G-E-R-I-C-K-R-R-I-A-A-R-K-I-P-A-G-H-R-V-T-V-D-D-A-I-A-F-L-N-E-S-Y-G-V-E-V-M"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-I-A-M-V-S-K-Q-P-R-K-Q-R-K-A-R-Y-A-A-P-L-H-I-R-Q-K-F-M-G-A-R-L-S-E-A-L-T-K-E-Y-G-T-R-S-A-A-V-I-T-G-D-T-V-K-V-M-R-G-D-F-K-G-T-E-G-K-V-Q-S-V-S-L-M-D-G-T-I-T-V-D-G-V-I-S-T-K-V-D-G-T-E-V-P-R-P-L-N-P-S-N-V-M-I-T-K-L-E-M-K-D-G-R-R-A-S-S-I-K-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-K-G-M-R-S-N-I-P-R-A-L-N-A-G-A-Q-I-A-C-V-D-N-T-G-A-K-V-V-E-I-I-S-V-K-K-Y-R-G-V-K-N-R-M-P-C-A-G-I-G-D-M-C-V-V-S-V-K-K-G-T-P-E-M-R-K-Q-V-L-L-A-V-V-V-R-Q-K-Q-E-F-R-R-P-D-G-L-H-V-S-F-E-D-N-A-M-V-I-T-D-E-E-G-I-P-K-G-T-D-I-K-G-P-V-A-R-E-V-A-E-R-F-P-K-I-G-T-T-A-S-I-I-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-R-D-I-G-L-N-I-P-A-P-S-E-E-C-D-D-A-Y-C-P-F-H-G-T-L-P-V-R-G-Q-I-L-V-G-T-V-V-S-S-K-M-D-N-T-V-V-I-E-R-Q-Y-M-K-M-V-S-K-Y-Q-R-Y-E-K-R-R-S-K-I-H-A-H-N-P-A-C-I-S-A-K-V-G-D-I-V-T-I-A-E-C-R-P-I-S-K-T-K-S-Y-V-V-V-K-A-E-V-P-K"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-R-S-K-V-E-I-L-P-S-N-L-I-F-H-E-L-I-G-L-E-I-K-V-I-N-S-T-N-P-S-L-T-G-I-R-G-R-V-I-N-E-T-K-N-M-L-V-V-E-N-S-Q-S-R-E-L-K-I-P-K-A-D-S-E-F-L-F-R-I-P-A-E-L-S-E-K-G-R-R-S-D-T-F-V-K-I-Q-G-N-L-L-L-S-Q-P-E-N-R-I-K-N-I-K-K-L-R-K-W-G"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-A-R-I-N-Y-S-I-N-G-D-P-E-T-T-S-K-A-M-G-S-E-L-H-I-S-P-K-K-S-R-E-V-C-C-K-I-K-G-M-K-A-S-E-A-R-K-F-L-E-D-V-I-A-M-K-Q-A-V-P-F-K-K-H-H-D-G-S-G-H-R-K-G-P-M-A-A-G-K-Y-P-I-S-A-S-K-E-I-L-K-V-L-K-N-A-E-S-N-A-E-Y-K-G-L-E-P-A-N-M-Y-I-I-H-A-A-I-Q-R-G-R-V-I-H-G-F-M-P-R-A-R-G-R-A-T-P-K-D-T-E-T-V-N-I-E-M-I-L-S-E-V-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-K-K-S-S-S-R-L-P-K-R-K-G-E-Y-T-Y-R-G-K-T-V-S-E-L-Q-E-L-S-L-E-E-F-A-E-L-L-P-S-R-E-R-R-S-L-K-R-G-F-T-D-G-Q-K-K-V-L-H-E-F-K-E-G-K-K-I-R-T-H-H-R-D-M-I-I-L-P-E-M-I-G-K-T-I-E-I-H-N-G-K-G-F-V-S-V-D-L-Q-P-E-M-V-G-H-R-F-G-E-F-A-P-T-R-S-R-V-S-H-G-S-A-G-V-G-A-T-R-S-S-K-F-V-P-L-K"} +{"text": "### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-S-S-I-N-Y-P-F-V-T-E-K-A-M-M-L-L-D-E-N-K-L-Q-F-I-V-D-T-R-S-N-K-K-Q-I-L-E-D-V-E-K-M-Y-G-F-K-V-K-S-V-R-T-M-T-T-M-K-G-M-K-K-A-V-L-A-F-E-E-P-E-A-A-H-E-I-A-T-R-I-G-L-M"} +{"text": "### FUNCTION Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase The precise role of the epsilon subunit is unclear ### SEQUENCE -M-V-D-T-A-K-N-T-K-L-F-T-S-Y-G-V-S-T-S-K-T-V-T-P-E-I-A-A-K-L-I-S-K-A-K-R-P-L-L-M-V-G-T-L-T-L-D-P-E-L-L-D-R-V-V-K-I-S-K-T-A-N-I-P-I-A-A-T-G-S-S-L-A-S-L-A-D-K-D-V-D-A-E-Y-I-N-A-H-M-L-G-F-Y-L-T-D-P-N-W-P-G-L-D-G-N-G-N-Y-D-T-V-I-V-L-G-F-K-K-F-Y-I-N-Q-V-L-S-A-A-K-N-F-S-N-L-K-T-I-A-I-E-R-G-Y-I-Q-N-A-T-M-S-F-G-N-L-S-K-A-D-H-Y-A-A-L-D-E-L-I-D-L-L"} +{"text": "### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-G-G-R-G-M-N-P-A-K-M-K-Q-M-M-K-Q-M-G-I-D-V-K-E-L-K-D-V-K-E-V-I-I-K-T-A-D-S-N-I-V-I-E-N-A-N-V-T-I-M-T-V-Q-G-S-E-T-Y-Q-I-V-G-D-A-K-E-V-P-K-S-L-E-I-P-A-D-D-I-K-L-V-M-E-Q-T-G-V-S-E-E-E-A-R-N-A-L-K-N-S-N-G-D-L-A-E-A-I-V-A-L-S-S-A"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-T-L-A-D-L-K-K-P-T-S-R-A-T-P-S-T-E-E-T-F-T-R-V-R-T-P-R-R-E-N-N-E-I-L-A-T-V-E-S-L-L-G-A-N-R-L-R-L-R-C-M-D-G-V-V-R-M-G-R-I-P-G-S-M-K-K-K-T-W-I-R-E-G-D-V-V-I-V-V-P-W-E-F-Q-N-E-K-A-D-V-I-W-K-Y-T-R-P-Q-V-D-W-L-E-R-K-G-Y-L-K-G"} +{"text": "### FUNCTION Involved in ribosome biogenesis ### SEQUENCE -M-G-Q-K-I-R-K-C-K-N-C-G-R-Y-T-L-R-E-K-C-P-V-C-G-G-V-T-L-P-A-I-P-A-R-F-S-P-Q-D-P-Y-G-K-Y-R-R-L-A-K-K-G"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-L-K-M-T-V-I-D-A-K-G-L-I-L-G-R-L-A-S-S-V-A-K-Q-L-L-S-G-D-E-K-V-Y-I-I-N-A-E-Q-A-I-I-S-G-S-R-A-A-T-L-R-E-Y-R-E-T-R-E-R-G-A-T-E-F-G-P-Y-F-P-K-R-P-D-R-I-L-K-R-T-I-R-G-M-L-P-Y-K-R-A-R-G-R-D-A-M-S-R-L-K-V-Y-V-G-V-P-Y-E-L-K-G-A-E-T-V-T-I-P-D-A-D-M-R-L-L-S-S-S-R-Y-V-E-L-G-E-V-S-Q-K-M-G-S-K-F"} +{"text": "### FUNCTION Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base ### SEQUENCE -M-E-E-K-N-R-V-G-K-K-E-D-R-I-M-G-I-N-N-G-T-G-Q-Q-H-P-K-I-F-L-S-G-S-I-R-G-G-R-Q-L-L-E-I-Y-R-L-M-Y-D-S-L-E-E-A-G-A-D-V-L-S-W-H-V-A-D-P-G-L-E-E-N-E-S-K-M-T-E-Q-E-I-Y-A-R-D-I-G-L-L-T-K-S-D-A-L-I-A-E-V-T-V-P-S-I-G-V-G-Y-E-I-C-R-A-L-V-R-K-I-P-V-L-C-L-H-R-P-E-A-A-V-S-A-M-V-L-G-N-P-D-P-S-L-E-V-R-T-Y-S-D-K-V-A-L-K-E-I-I-V-E-F-A-L-A-L"} +{"text": "### FUNCTION Excises hypoxanthine, a deamination product of adenine, from double-stranded DNA Acts on double-stranded DNA containing G/I, T/I, A/I and C/I base pairs, but not on single-stranded inosine-containing DNA Has also minor xanthine DNA glycosylase activity Lacks any detectable uracil-DNA glycosylase activity ### SEQUENCE -M-I-K-R-G-F-P-A-V-L-D-E-N-T-E-I-L-I-L-G-S-L-P-S-D-E-S-I-R-K-Q-Q-Y-Y-G-N-P-G-N-D-F-W-R-L-V-G-H-A-I-G-E-N-L-Q-D-M-A-Y-E-K-K-L-K-T-L-K-H-N-R-I-G-L-W-D-V-F-K-A-G-S-R-E-G-S-Q-D-S-K-I-G-D-E-E-I-N-D-F-S-G-L-K-E-M-V-P-K-L-R-L-I-C-F-N-G-R-K-A-G-E-Y-E-P-L-L-R-G-M-G-Y-E-T-K-V-L-P-S-S-S-G-A-N-R-R-F-S-K-N-R-E-S-E-W-E-A-V-F-R-H"} +{"text": "### FUNCTION Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP ### SEQUENCE -M-K-D-K-G-K-L-V-I-W-P-A-Y-I-D-Q-T-R-S-R-S-N-G-R-I-I-S-R-K-N-A-V-K-E-P-H-L-N-E-I-K-D-A-A-K-N-L-G-L-N-P-E-V-E-P-E-K-A-Y-P-K-S-W-W-E-V-S-G-R-V-L-V-D-D-R-G-P-K-S-V-I-A-K-Q-I-S-L-E-I-R-K-K-R-G-K-G-V-P-A-K-T"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-E-S-T-I-T-I-E-N-V-V-A-S-T-A-L-A-T-E-F-D-L-V-K-I-M-D-S-G-L-E-G-A-E-Y-N-K-T-K-F-P-G-L-V-Y-R-I-D-N-P-K-A-A-F-L-I-F-T-S-G-K-V-V-C-T-G-A-K-T-I-N-N-A-H-K-A-I-T-N-L-A-N-K-L-K-D-I-G-C-D-K-I-N-L-E-P-E-I-H-V-Q-N-I-V-A-S-A-D-L-K-T-T-L-N-L-N-T-I-A-I-A-F-G-L-E-N-V-E-Y-E-P-E-V-F-P-G-L-I-Y-R-V-E-A-P-K-V-V-V-L-V-F-S-S-G-K-L-V-I-T-G-G-K-C-E-E-D-C-N-G-G-L-R-I-V-R-K-E-F-D-N-L-G-L-L-C"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently ### SEQUENCE -M-P-S-Q-G-K-K-Y-E-Y-L-E-H-T-A-D-I-K-F-L-A-Y-G-N-T-L-K-E-V-F-E-N-A-A-L-A-M-F-N-V-I-I-D-T-G-K-V-S-G-E-T-A-R-E-V-C-L-T-S-P-D-L-E-S-L-L-V-D-W-L-S-E-L-L-Y-L-F-E-V-D-E-I-V-F-W-K-F-R-V-E-E-I-R-E-E-E-G-E-Y-S-I-K-A-V-A-S-G-E-Q-Y-Y-P-E-S-H-P-F-E-T-E-I-K-A-V-T-Y-N-Q-L-E-L-E-K-T-A-D-G-W-K-A-Q-V-V-V-D-I"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-G-R-A-W-K-F-G-D-D-V-D-T-D-A-V-I-P-G-R-Y-L-I-F-N-T-P-G-E-L-A-K-Y-T-F-E-G-V-R-P-D-F-A-K-K-V-H-E-N-D-I-V-V-A-G-S-N-F-G-C-G-S-S-R-E-H-A-P-L-A-L-K-G-S-K-V-S-C-V-I-A-K-S-F-A-R-I-F-F-R-N-A-I-N-I-G-V-P-V-L-E-C-P-N-T-D-R-I-D-D-G-D-E-L-E-V-D-L-S-T-G-D-I-Q-N-I-T-K-G-E-T-Y-Q-A-T-P-L-P-D-F-V-R-E-I-V-D-E-G-G-L-I-E-Y-A-R-K-L-V-S-E-R"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-E-P-T-I-T-I-E-N-I-V-A-S-T-R-L-A-E-D-F-D-L-Q-K-L-L-D-T-G-L-K-G-A-V-Y-N-K-N-K-F-P-G-L-V-Y-R-I-E-N-P-K-A-A-F-L-I-F-A-S-G-K-V-V-C-T-G-T-K-N-V-E-N-S-R-I-A-L-F-N-L-A-N-E-L-N-S-I-G-Y-K-G-I-Y-L-K-P-E-I-H-V-Q-N-V-V-A-S-A-N-L-R-T-S-L-N-L-N-A-V-L-S-A-F-G-V-E-N-V-E-Y-E-P-E-V-F-P-G-L-V-Y-K-L-A-D-P-R-V-V-V-L-V-F-R-T-G-K-L-V-I-T-G-G-K-C-P-E-D-C-E-E-G-L-R-I-I-K-T-Q-L-D-N-L-G-L-L-Y"} +{"text": "### FUNCTION Probable toxic component of a putative type VII toxin-antitoxin system, probably an RNase Probably neutralized by cognate antitoxin MA_102 Neutralization may be due to AMPylation by MA_102 ### SEQUENCE -M-K-E-K-R-E-F-R-D-Y-L-S-D-I-F-D-A-I-E-K-I-E-N-F-T-Q-D-I-S-F-D-A-F-V-E-D-E-M-R-V-F-A-V-V-R-A-L-E-I-I-G-E-A-A-K-N-V-P-L-E-I-K-E-N-Y-P-S-V-P-W-K-E-M-A-R-T-R-D-K-L-I-H-S-Y-F-G-V-D-L-N-V-V-W-K-T-V-N-K-N-L-P-P-L-K-D-Q-I-S-E-I-L-K-D-L-G-N-T-S-S"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-A-D-P-G-I-V-M-V-G-I-G-D-C-A-I-A-R-C-P-V-K-I-K-T-S-G-L-G-S-C-V-G-V-T-I-Y-D-R-H-E-K-I-G-G-L-L-H-T-M-L-P-N-I-K-K-A-G-I-K-D-N-P-T-K-F-T-D-A-G-I-E-Y-L-V-A-E-I-I-E-N-G-G-S-R-R-K-L-E-A-K-L-V-G-G-S-S-M-F-E-N-S-H-M-N-I-G-E-R-N-I-K-S-A-K-E-T-L-K-K-L-G-L-E-I-I-A-E-D-T-G-K-N-Y-G-R-T-I-I-F-D-T-L-T-G-D-L-L-I-K-T-M-L-R-G-D-K-V-I"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-A-E-K-K-N-E-Q-E-I-Q-Q-E-L-Q-R-L-I-A-E-I-N-R-L-Q-G-Q-M-E-A-I-N-A-Q-I-D-L-I-E-S-S-I-S-E-L-N-R-V-E-E-T-L-K-G-V-K-E-L-E-G-D-E-E-V-L-V-P-V-G-A-Q-S-F-V-R-A-C-V-T-D-T-E-R-V-I-V-G-I-G-A-G-V-A-V-E-R-T-I-D-E-A-L-E-S-I-D-D-Q-R-Q-E-L-E-K-A-R-A-E-A-Q-Q-K-L-Q-E-L-A-Q-E-L-Q-E-K-Q-R-K-A-Q-E-L-A-Q-Q-L-E-G-A-Q-R-I-A-Q-Q-S-G-G-G"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-Y-K-Q-V-I-V-V-R-G-D-L-K-L-S-R-G-K-L-A-A-Q-V-A-H-A-S-L-G-A-F-L-R-A-K-E-S-G-A-P-V-E-E-W-L-R-E-G-Q-K-K-V-V-L-K-C-K-D-K-E-E-L-L-E-L-H-E-L-A-K-R-R-G-L-P-S-F-L-V-R-D-A-G-L-T-E-L-E-P-G-T-V-T-C-L-G-I-G-P-E-R-E-E-E-I-D-R-V-T-G-D-L-P-L-L-R"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-I-L-G-E-Y-V-L-R-D-L-F-P-D-L-D-E-D-Q-Y-Q-P-A-G-I-D-L-K-L-D-R-V-F-R-L-E-G-R-G-A-L-L-E-G-D-D-K-R-L-P-E-Y-R-E-V-E-T-E-G-G-V-F-E-L-E-P-N-V-P-Y-V-L-E-L-A-P-E-L-E-I-P-E-D-T-A-V-L-F-L-P-R-S-T-L-L-R-S-G-V-S-V-H-T-A-L-G-D-P-G-F-R-G-K-I-R-V-L-A-V-N-H-H-A-A-P-Y-R-I-A-H-G-E-R-V-V-Q-A-V-F-L-R-A-E-D-A-G-R-Y-E-G-D-Y-G-R"} +{"text": "### FUNCTION Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP ### SEQUENCE -M-A-E-T-P-T-V-K-L-K-G-K-D-R-I-V-V-W-P-A-Y-F-D-A-D-R-S-R-S-E-G-R-K-V-P-K-R-L-A-V-R-N-P-R-L-T-E-L-R-H-I-A-E-K-L-G-L-N-P-K-V-Q-R-D-K-R-Y-P-K-R-W-W-D-D-K-G-R-L-I-V-D-K-V-E-S-K-R-K-T-L-L-M-I-A-E-K-L-K-E-R-R-E-S"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-V-A-Q-S-V-L-E-T-V-L-D-V-A-R-K-R-G-A-E-R-V-L-S-V-R-L-R-I-G-E-F-T-L-L-N-P-E-Q-L-R-F-C-L-E-V-L-A-E-G-T-P-V-E-G-A-K-F-E-I-E-I-E-R-G-Y-F-K-C-A-E-C-G-H-R-W-R-P-E-D-E-S-L-K-D-P-S-L-H-T-A-F-D-L-S-E-L-T-E-L-L-D-L-K-C-P-K-C-G-S-R-A-V-K-L-D-G-G-D-A-C-S-I-E-S-V-R-L-E-V-P-G-E-Q-H-A-Q-G"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-N-K-G-E-D-N-L-V-R-T-S-I-T-V-P-E-Q-L-L-Q-K-V-N-E-L-I-A-S-G-Y-F-A-S-R-S-E-I-F-R-Q-A-L-R-E-Y-L-Q-R-I-E-W-T-E-R-V-G-D-E-E-Y-F-G-A-L-T-Y-V-F-Q-H-E-R-A-E-P-E-L-V-K-V-Q-H-E-F-T-D-V-I-I-S-T-T-H-I-H-V-S-P-E-K-C-L-E-V-L-L-L-Q-G-P-G-K-R-I-A-E-L-A-K-R-I-R-G-V-R-G-V-E-Q-A-K-L-T-V-V-S-S-E-G-E"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-I-V-A-L-K-V-K-R-I-E-M-G-T-V-L-D-H-L-P-P-G-T-A-P-Q-I-M-R-I-L-D-I-D-P-T-E-T-T-L-L-V-A-I-N-V-E-S-S-K-M-G-R-K-D-I-L-K-I-E-G-K-I-L-S-E-E-E-A-N-K-V-A-L-V-A-P-N-A-T-V-N-I-V-R-D-Y-S-V-A-E-K-F-Q-V-K-P-P-E-R-V-E-G-F-L-R-C-P-N-P-N-C-I-T-N-D-E-R-E-P-V-D-T-V-F-V-R-E-S-K-K-P-L-E-Y-R-C-R-Y-C-E-R-T-V-R-E-D-Q-I-R-E-L-I-R-P-S"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-V-E-Y-A-H-S-K-P-V-D-P-E-E-W-T-V-I-D-A-E-N-A-V-L-G-R-L-A-S-V-V-A-K-R-I-L-K-G-E-R-I-A-V-I-N-T-E-K-A-I-I-T-G-K-K-N-T-I-K-E-E-W-L-Q-K-I-Q-R-G-D-P-K-K-G-P-F-Y-P-R-R-P-D-L-I-F-R-R-V-V-R-G-M-L-P-W-K-T-K-R-G-R-E-A-F-K-R-L-R-A-Y-I-G-T-P-R-W-V-E-E-A-N-I-E-P-E-R-V-A-E-A-D-M-S-R-L-G-H-L-W-Y-V-T-L-G-E-L-S-E-E-L-G-Y-Q-M-P-G-G-Q"} +{"text": "### FUNCTION Located on the platform of the 30S subunit ### SEQUENCE -M-A-E-K-E-G-K-K-E-K-K-E-R-W-G-I-A-H-I-Y-A-S-F-N-N-T-I-I-T-I-T-D-L-T-G-A-E-T-F-A-R-W-S-G-G-M-V-V-D-A-D-R-E-E-S-S-P-Y-A-A-M-K-A-A-R-R-A-A-E-E-A-M-E-K-G-I-T-A-V-H-V-K-V-R-A-P-G-G-H-G-P-K-T-P-G-P-G-A-Q-A-A-I-R-A-L-A-R-A-G-L-K-I-G-R-I-E-D-V-T-P-I-P-H-D-G-T-R-R-P-G-G-K-R-G-R-R-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-G-D-P-K-R-P-R-K-K-Y-E-T-P-R-H-P-W-E-A-E-R-L-E-Y-E-R-K-L-M-R-K-Y-G-L-R-R-K-K-E-L-W-R-H-Q-T-Q-L-K-R-W-R-E-R-A-K-E-L-M-A-R-T-D-P-E-A-Q-R-E-R-E-A-L-F-R-K-L-Y-D-L-G-I-L-D-K-K-P-E-E-A-T-L-D-D-I-L-R-L-T-V-E-D-V-L-E-R-R-L-Q-T-I-V-Y-R-K-G-L-A-K-T-P-L-Q-A-R-Q-L-V-V-H-R-H-I-A-I-G-D-R-I-V-T-V-P-S-Y-L-V-S-R-E-E-E-E-E-V-D-Y-S-P-Y-S-P-L-K-D-E-D-H-P-I-R-C-E-A-R-G-E-S-P-E-E-T-A-A-E-E"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-D-D-E-V-K-P-I-V-R-I-A-D-V-D-L-D-G-H-K-K-V-P-Y-A-L-T-G-I-K-G-I-G-I-R-M-A-Y-A-I-C-R-E-L-G-L-D-E-E-K-K-L-G-E-L-S-D-E-E-I-E-R-I-E-E-E-I-K-K-L-S-E-G-E-S-N-I-P-S-W-M-Y-N-R-Q-K-D-Y-E-T-G-E-D-M-H-L-V-G-A-E-L-E-M-T-V-K-Q-D-I-D-R-L-K-K-I-R-A-Y-R-G-I-R-H-E-L-G-L-P-V-R-G-Q-R-T-K-S-S-F-R-R-G-R-T-V-G-V-K-K-K-Q"} +{"text": "### FUNCTION Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A ### SEQUENCE -M-T-V-V-L-R-L-P-R-E-L-R-P-E-L-R-R-P-W-G-T-L-Y-P-R-P-S-I-K-T-Y-R-R-L-H-E-E-S-E-V-L-I-T-V-G-D-M-T-T-R-S-F-L-R-C-S-I-R-P-D-V-A-V-V-D-R-K-M-L-R-T-V-P-V-D-P-G-N-K-F-P-V-T-L-D-V-N-N-P-P-G-T-I-T-R-E-A-W-D-T-V-R-R-G-I-D-Y-A-L-D-G-D-A-T-L-I-D-V-T-G-E-E-D-L-L-A-I-P-A-I-L-I-A-P-E-N-S-I-V-C-Y-G-L-P-G-E-G-M-V-A-A-R-V-T-Q-H-L-K-D-S-V-L-R-L-L-T-R-F-R-G-Y-D-E-W-K-S-R-S-W-I-S-G-I-T-P-C-C-T-A-K-R"} +{"text": "### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate forming two phosphate ions ### SEQUENCE -M-M-N-L-W-K-D-L-E-P-G-P-N-P-P-D-V-V-Y-A-V-I-E-I-P-R-G-S-R-N-K-Y-E-Y-D-E-E-R-G-F-F-K-L-D-R-V-L-Y-S-P-F-H-Y-P-L-D-Y-G-F-I-P-R-T-L-Y-D-D-G-D-P-L-D-I-L-V-I-M-Q-D-P-T-F-P-G-C-V-I-E-A-R-P-I-G-L-M-K-M-L-D-D-S-D-Q-D-D-K-V-L-A-V-P-T-E-D-P-R-F-K-D-V-K-D-L-D-D-V-P-K-H-L-L-D-E-I-A-H-M-F-S-E-Y-K-R-L-E-G-K-E-T-E-V-L-G-W-E-G-A-D-A-A-K-E-A-I-V-H-A-I-E-L-Y-E-E-E-H-G"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-G-V-L-G-G-P-S-P-R-L-R-L-Y-V-Y-D-F-K-E-P-G-G-E-A-E-R-R-K-L-R-E-L-L-E-S-H-G-A-F-R-L-Q-Y-S-T-Y-A-L-L-A-E-P-E-V-H-A-R-V-L-R-R-V-V-A-R-V-D-F-E-E-G-D-S-L-I-V-V-P-M-C-R-R-C-L-R-V-A-R-W-V-D-A-E-G-V-R-G-L-R-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-L-M-D-P-L-A-D-A-M-A-T-I-K-N-N-E-M-V-G-N-K-E-C-V-I-E-P-A-S-K-L-I-G-R-V-L-K-V-M-Q-E-Y-G-Y-I-G-S-F-E-F-I-D-D-G-R-S-G-K-F-L-V-K-L-V-G-R-I-N-D-C-G-V-I-K-P-R-H-P-V-K-K-D-E-W-E-Y-W-E-Q-R-Y-L-P-A-R-D-F-G-L-L-I-V-T-T-P-E-G-V-M-S-H-Y-E-A-K-E-R-G-I-G-G-R-L-L-A-Y-V-Y"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-R-R-E-F-G-K-G-A-R-R-C-R-R-C-G-D-T-H-G-V-I-Q-K-Y-G-I-M-L-C-R-Q-C-F-R-E-V-A-E-K-M-G-F-K-K-Y-N"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-V-V-D-E-E-T-R-R-K-I-L-E-D-W-E-S-N-P-M-R-K-P-R-V-G-K-V-T-V-N-I-G-V-G-E-S-G-D-R-L-Q-K-A-Y-E-L-L-Q-E-L-T-G-Q-K-P-V-Y-T-R-A-K-Q-T-N-P-S-F-G-I-R-R-G-Q-P-I-G-V-K-V-D-L-R-R-E-Q-A-I-E-F-L-D-W-T-L-D-A-V-D-R-E-L-H-E-S-Q-F-D-E-F-G-N-V-C-F-G-L-E-E-H-I-A-L-E-G-V-E-Y-D-P-E-I-G-I-F-G-M-D-I-A-V-T-L-E-R-P-G-F-R-V-M-R-R-R-R-C-R-R-P-V-P-R-R-H-R-L-T-K-E-E-G-I-V-F-M-E-E-E-F-D-V-E-V-L-P"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-R-W-T-K-S-S-Q-P-R-K-Q-R-K-A-F-F-N-A-P-L-H-K-R-Q-K-L-M-S-A-T-L-H-P-E-L-R-K-K-F-N-R-R-S-L-P-V-R-R-G-D-M-V-R-I-M-R-G-D-F-K-G-H-E-G-E-V-V-E-V-D-L-K-R-L-R-I-Y-V-E-G-A-T-I-E-R-A-N-G-E-K-V-Y-Y-P-I-H-P-S-N-V-M-I-I-E-P-N-L-D-D-P-M-R-R-K-I-I-E-R-S-G-G-T-P-E-V-E-A-V-P-E-K-S-E-E-E-K-E-E-K-E-K-E-E-E-K-S-E-E"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-K-A-I-K-A-K-S-P-H-A-A-L-P-V-G-A-R-L-V-C-A-D-N-T-G-A-R-E-L-Q-I-I-A-V-K-G-Y-K-G-V-R-R-R-L-P-N-A-G-I-G-D-M-V-V-C-S-V-K-E-G-T-P-D-M-R-K-E-V-V-N-A-V-I-V-R-Q-R-K-E-Y-R-R-P-D-G-T-R-V-K-F-E-D-N-A-A-V-I-V-T-P-D-G-A-P-R-G-S-E-I-R-G-P-V-A-K-E-A-A-E-R-W-P-R-I-G-S-I-A-S-I-I-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-T-G-E-Y-R-M-A-K-D-I-G-L-G-V-K-P-P-R-R-E-C-D-D-P-N-C-P-F-H-G-N-L-R-V-R-G-M-I-L-E-G-V-V-V-S-D-R-M-D-K-T-V-I-V-E-R-E-Y-Y-R-Y-D-R-K-Y-E-R-W-E-R-R-R-S-R-I-P-A-H-N-P-P-C-I-D-A-Q-E-G-D-K-V-R-I-A-E-C-R-P-L-S-K-T-K-S-F-V-V-I-E-V-L-E-R-A-Q-E-R"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-V-K-I-G-A-R-E-L-A-A-V-A-I-G-G-A-L-G-A-V-C-R-Y-L-L-S-G-L-V-P-Q-V-R-G-F-P-M-G-T-V-L-V-N-V-L-G-S-F-V-L-G-F-L-T-W-S-T-M-L-G-L-R-L-S-P-E-V-R-A-L-A-T-V-G-F-C-G-G-L-T-T-L-S-T-M-A-Y-E-T-V-E-L-L-K-A-S-P-V-L-S-I-L-Y-L-T-A-N-V-V-L-G-I-A-A-V-L-G-G-M-A-A-A-H-V-V-W-S-G-R-A"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-R-W-S-G-R-A-H-V-F-G-D-D-V-D-T-D-Q-I-I-P-G-R-C-L-R-R-V-S-Y-D-E-L-G-R-Y-A-M-T-G-A-D-P-E-F-P-E-K-V-R-E-G-D-V-I-V-A-G-K-N-F-G-C-G-S-S-R-E-Q-A-V-M-A-L-Q-Q-A-G-V-A-C-V-V-A-R-S-F-A-R-I-F-Y-R-N-A-I-N-R-G-L-P-T-V-E-A-E-E-D-P-T-E-V-V-E-D-G-N-R-V-T-V-D-L-D-E-L-V-L-R-A-G-S-E-E-V-P-L-R-E-P-P-E-F-A-L-Q-A-W-R-E-G-G-L-L-E-L-V-K-K-N-P-D-K-P-P-W-R-D"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-A-E-E-N-V-I-Y-V-G-N-K-P-V-T-N-Y-V-L-A-V-M-T-Q-F-S-E-G-A-D-E-V-K-L-V-A-R-G-R-A-I-S-R-A-V-D-V-A-E-F-I-R-N-N-V-M-P-E-V-E-V-K-D-I-E-I-G-T-E-E-I-E-T-E-E-G-D-T-I-S-V-S-T-I-A-I-T-L-A-K-P-S-E"} +{"text": "### FUNCTION Catalyzes the formation of CDP-2,3-bis- and CTP This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-V-E-M-G-S-G-A-W-L-E-L-G-K-G-L-W-F-I-L-P-A-Y-I-A-N-L-S-A-C-L-F-G-G-G-R-P-L-D-F-G-K-K-L-S-D-G-R-R-L-L-G-D-G-V-T-I-R-G-F-I-V-G-V-L-A-G-A-V-V-G-L-G-E-G-L-V-V-G-D-P-W-K-A-G-D-G-F-I-L-G-L-G-A-M-A-G-D-A-V-G-S-F-V-K-R-R-I-G-L-E-R-G-A-P-A-P-V-L-D-Q-L-D-F-F-V-G-A-V-L-L-Y-Y-L-V-Y-G-W-H-P-P-G-W-V-L-V-G-L-A-I-L-T-L-A-L-H-W-L-T-N-V-I-G-Y-L-L-K-L-K-E-V-P-W"} +{"text": "### FUNCTION Broad-specificity nucleoside monophosphate kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-K-I-A-I-T-G-T-P-G-V-G-K-T-T-V-C-E-A-L-R-D-L-G-F-D-V-V-H-L-N-K-V-A-R-E-M-D-A-I-L-E-E-D-E-Q-R-Q-A-K-V-V-D-L-H-A-L-R-R-Y-V-E-E-W-E-P-E-S-D-P-A-F-V-E-S-H-Y-A-H-L-M-P-T-D-L-V-I-V-L-R-L-H-P-S-E-L-E-R-R-L-K-E-K-G-Y-P-P-E-K-I-A-E-N-L-E-A-E-F-V-G-V-C-Y-G-E-A-V-E-V-R-S-E-G-C-F-I-R-P-P-E-D-V-I-Q-V-N-V-T-G-L-S-R-A-E-A-A-D-R-V-L-E-A-V-N-H-R-R-G-D-D-V-D-W-L-S-D-E-E-A-Q-R-T-V-E-R-Y-L-K-Y-R"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-G-V-E-E-L-E-R-K-I-L-E-D-A-E-K-E-A-E-E-I-L-E-E-A-K-R-D-A-E-R-I-R-E-K-A-E-R-E-A-E-E-V-R-R-E-I-L-D-R-A-R-R-E-A-E-T-R-R-R-R-E-I-A-Q-A-K-L-E-I-R-Q-E-R-L-R-V-K-E-E-Y-I-E-K-A-I-E-R-A-E-E-K-I-R-E-L-A-E-E-G-R-K-E-Y-L-E-F-L-K-R-S-A-I-E-A-V-N-A-I-S-S-D-E-V-V-L-R-A-N-E-N-D-L-M-L-L-D-E-M-L-S-E-I-R-D-E-T-G-K-D-V-E-L-G-E-P-V-E-A-V-G-G-V-I-A-E-S-K-D-G-S-E-A-Y-D-N-T-V-D-A-R-L-R-R-R-R-S-E-I-V-R-R-V-S-E-T-L-F-G-G"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-E-E-R-S-K-D-D-I-P-D-W-W-E-K-E-W-V-E-F-R-Y-R-G-Y-T-L-G-E-L-M-K-M-P-I-E-E-F-I-E-L-L-P-A-R-Q-R-R-S-L-K-R-G-L-P-S-R-H-K-K-L-L-R-K-V-R-R-A-R-R-L-L-R-R-G-K-K-P-P-V-I-R-T-H-C-R-D-M-I-I-L-P-E-M-V-G-L-T-I-A-V-Y-N-G-K-E-F-K-E-V-K-I-E-P-E-M-I-G-H-Y-L-G-E-F-A-K-T-R-K-T-V-E-H-G-G-I-G-A-T-R-S-S-L-F-V-P-L-K"} +{"text": "### FUNCTION eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA ### SEQUENCE -M-V-E-Y-D-Y-E-E-L-L-E-R-A-Y-E-Q-L-P-E-E-V-L-E-D-R-R-F-E-M-P-K-P-K-V-S-V-E-G-K-T-T-V-I-R-N-F-K-E-I-S-K-K-L-D-R-D-P-E-H-I-T-K-Y-F-L-K-E-L-G-T-A-G-H-V-D-G-G-R-L-I-L-H-G-V-Y-H-P-K-L-V-E-E-E-L-K-N-Y-V-E-E-F-V-L-C-P-E-C-G-K-P-D-T-K-L-V-R-E-D-R-Q-W-I-L-K-C-E-A-C-G-A-W-S-S-V-R-R-L-K"} +{"text": "### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-F-P-G-G-K-I-D-P-R-K-L-Q-R-L-M-R-E-M-G-M-E-Q-E-P-I-S-G-V-E-R-V-E-I-H-L-K-D-G-S-K-L-V-F-E-K-P-Q-V-I-R-M-K-I-M-N-Q-E-F-Y-Q-V-A-G-K-A-K-R-E-K-P-E-E-E-P-F-T-D-E-D-V-K-L-V-A-E-Q-A-G-V-S-E-E-E-A-R-K-A-L-E-E-T-G-G-D-L-A-E-A-I-M-R-L-Q-G-E"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-P-K-T-K-H-W-H-Y-S-I-P-P-E-E-L-D-D-E-R-T-A-K-A-F-I-R-E-L-R-I-S-P-K-H-A-R-E-I-C-R-A-I-R-G-M-P-L-D-R-A-K-E-F-L-R-R-V-I-R-K-E-E-A-V-P-F-R-K-H-K-K-K-V-P-H-R-R-Q-I-R-P-G-W-D-A-G-R-F-P-E-K-A-A-R-E-I-L-R-V-L-E-H-A-E-A-N-A-E-Y-K-G-L-D-T-D-R-L-Y-I-K-H-I-A-A-H-K-G-R-V-I-R-G-W-I-P-R-A-F-G-R-A-T-P-F-N-T-P-T-T-H-I-E-V-I-L-E-E-R"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-E-I-Q-N-I-V-A-S-V-D-L-K-G-E-V-N-L-D-E-C-S-V-I-L-Q-G-E-Y-E-P-E-Q-F-P-G-L-V-Y-R-L-E-D-I-G-T-V-V-L-I-F-R-S-G-K-M-V-C-T-G-A-K-N-R-E-Q-I-Y-K-S-V-E-R-V-R-E-D-L-E-K-K-C-G-V-K-F-H-G-E-P-E-V-E-I-Q-N-I-V-A-S-I-D-F-H-V-P-L-D-L-D-T-I-A-E-V-L-V-G-D-E-D-V-E-G-I-E-Y-E-P-E-Q-F-P-G-L-V-L-R-L-R-E-P-K-V-A-M-L-L-F-Y-S-G-K-A-V-C-T-G-A-K-T-E-E-E-P-E-K-A-V-K-K-I-A-E-K-I-E-K-Y-G-L-K-L-T-G"} +{"text": "### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-P-H-N-V-V-L-T-G-R-P-G-I-G-K-T-T-V-C-L-K-V-R-N-V-L-E-E-E-G-Y-T-V-G-G-I-Y-C-P-E-I-R-E-G-G-R-R-I-G-F-E-I-V-D-L-T-E-G-D-R-Y-L-L-A-R-E-G-A-S-G-P-R-V-G-R-Y-G-V-F-V-D-N-L-E-R-A-A-E-S-I-E-R-A-V-K-R-T-D-V-V-I-V-D-E-V-G-P-M-E-L-K-S-N-A-F-V-D-A-V-R-R-A-A-D-A-H-T-P-A-I-F-V-V-H-E-R-S-R-H-P-V-V-V-D-L-R-E-E-R-P-D-V-V-R-F-R-V-T-L-S-N-R-D-E-L-S-D-R-I-L-E-H-V-L-E-W-L-E-E-R"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-P-K-E-E-V-E-V-L-I-E-G-G-K-A-D-P-G-P-P-L-G-P-A-L-G-P-L-G-V-N-I-Q-E-V-V-E-E-I-N-R-K-T-K-D-F-K-G-M-E-V-P-V-K-I-I-V-D-T-E-T-R-E-F-E-V-K-V-G-S-P-P-T-S-A-I-I-K-S-E-L-G-I-D-K-G-A-H-E-P-R-H-E-T-V-G-D-L-S-M-E-Q-V-I-K-I-A-K-M-K-F-D-D-L-L-S-Y-D-L-K-T-A-A-K-E-I-L-G-T-C-G-S-M-G-V-T-V-E-G-K-D-P-K-E-V-Q-K-E-I-D-E-G-K-W-D-D-L-F-E-K-Y-E-E-E-E-E"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-S-T-Y-E-E-L-I-S-L-L-R-D-C-K-R-V-L-R-A-A-R-K-P-T-W-D-E-Y-I-E-S-A-K-I-A-G-L-G-I-L-I-V-G-G-V-G-F-L-I-R-V-I-V-Q-L-I-E-L-Y-T"} +{"text": "### FUNCTION Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs ### SEQUENCE -M-E-L-E-P-R-T-V-V-L-R-L-G-H-R-R-E-R-D-K-R-I-T-T-H-V-C-L-T-A-R-A-F-G-A-A-G-V-L-I-S-G-D-H-D-E-S-V-I-E-S-V-E-D-V-V-E-R-W-G-G-P-F-T-V-Q-W-V-G-N-W-R-R-V-I-K-D-W-K-R-S-G-G-S-V-V-H-L-T-M-Y-G-L-H-I-D-D-V-I-G-E-L-R-G-E-N-E-L-L-V-I-V-G-A-G-K-V-P-A-E-V-F-E-L-S-D-Y-N-V-A-I-G-H-Q-P-H-S-E-V-A-A-L-A-V-F-L-D-R-L-Y-E-G-K-E-L-H-R-E-F-E-R-A-R-L-R-V-V-P-S-E-K-G-K-K-V-E-R-L"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-R-D-V-I-R-G-R-A-W-V-F-G-D-D-I-D-T-D-Q-I-I-P-G-R-Y-L-T-T-Q-D-P-E-E-L-A-K-H-V-M-E-G-A-D-P-E-F-P-E-K-V-R-E-G-D-V-I-V-A-G-K-N-F-G-C-G-S-S-R-E-H-A-P-I-A-L-K-A-A-G-I-A-C-V-V-T-R-S-F-A-R-I-F-Y-R-N-A-I-N-L-G-L-P-L-V-V-C-P-G-V-D-D-A-F-E-D-G-Q-G-I-E-V-N-L-R-E-G-Y-V-R-N-L-D-T-G-E-E-L-E-A-K-P-L-P-D-F-M-M-R-I-L-E-A-G-G-L-V-E-L-I-K-R-E-G-P-R-A-F-E-G"} +{"text": "### FUNCTION Functions by promoting the formation of the first peptide bond ### SEQUENCE -M-D-V-A-V-K-K-V-E-V-R-Q-L-K-K-G-K-Y-I-M-I-D-D-E-P-C-K-I-V-E-Y-T-T-S-S-P-G-K-H-G-S-A-K-A-R-I-V-A-V-G-L-F-D-G-K-K-R-T-L-T-K-P-V-D-A-K-V-D-V-P-V-I-E-R-K-T-A-Q-V-V-S-D-M-G-D-T-V-Q-L-M-D-M-E-T-Y-E-T-F-E-V-Q-K-P-E-D-E-E-L-A-S-Q-L-E-P-G-T-M-V-E-Y-M-E-A-A-G-K-R-K-I-V-G-I-K-E-E-E"} +{"text": "### FUNCTION Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase The precise role of the epsilon subunit is unclear ### SEQUENCE -M-P-L-P-R-D-P-T-L-I-Y-T-D-K-A-E-V-A-R-A-P-V-L-K-M-V-F-R-R-A-N-D-S-L-M-I-V-G-P-R-A-V-E-D-E-E-W-R-E-L-L-M-K-L-R-E-E-F-R-M-S-A-V-C-T-A-P-Y-K-G-N-D-L-G-R-K-M-G-I-V-E-A-A-T-L-L-Q-R-D-A-P-V-L-G-V-H-P-D-L-V-V-F-T-G-S-R-T-D-V-T-D-R-V-L-Q-G-L-R-H-A-R-P-D-L-V-K-V-S-L-N-P-E-Y-C-P-S-A-D-Y-S-L-P-T-V-K-R-D-Q-F-L-Q-E-L-K-A-L-V-G-I"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-A-E-E-E-N-V-V-Y-V-G-S-K-P-V-M-N-Y-V-L-A-C-I-T-Q-F-N-E-G-A-N-E-V-R-I-K-A-R-G-R-A-I-S-R-A-V-D-V-A-E-I-V-R-N-R-F-M-P-E-V-E-V-K-D-I-K-I-G-T-E-E-L-E-T-E-E-G-D-T-V-N-V-S-T-I-E-I-V-L-E-K-P-V"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-G-K-K-S-P-A-G-E-F-A-A-R-K-L-R-E-K-R-K-K-F-R-W-K-D-E-R-Y-K-R-R-M-L-K-L-D-E-K-A-D-P-L-E-G-A-P-Q-A-R-G-I-V-L-E-K-V-G-V-E-A-K-Q-P-N-S-A-I-R-K-C-V-R-V-Q-L-I-K-N-G-K-Q-V-T-A-F-C-P-G-D-G-A-I-D-Y-I-D-E-H-D-E-V-V-I-E-G-I-G-G-P-K-G-R-A-K-G-D-I-P-G-V-R-Y-K-V-V-K-V-N-D-V-A-L-S-E-L-L-K-G-K-I-E-K-P-M-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center ### SEQUENCE -M-E-G-N-P-Y-L-D-R-L-Y-E-M-K-V-F-G-K-W-D-P-T-E-V-E-V-R-D-P-G-L-K-D-Y-I-C-L-K-P-M-Y-L-P-H-T-G-G-R-H-A-K-K-R-F-A-K-A-E-V-P-I-V-E-R-L-I-N-R-V-M-R-T-E-K-N-T-G-K-K-H-L-A-Y-N-I-V-K-R-A-F-D-I-I-H-E-R-T-G-E-N-P-I-Q-V-L-V-Q-A-L-E-N-A-A-P-R-E-E-T-T-T-I-I-Y-G-G-I-S-Y-H-E-A-V-D-S-S-P-Q-R-R-L-D-I-A-L-R-L-I-T-E-G-A-Q-Q-R-A-F-R-N-P-K-P-I-E-E-C-L-A-E-E-I-I-A-A-A-R-Y-D-T-E-C-H-S-I-R-R-K-E-E-I-E-R-I-A-E-A-A-R"} +{"text": "### FUNCTION Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in Mjannaschii 16S rRNA It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3- ### SEQUENCE -M-I-V-L-H-A-R-D-C-D-P-K-A-C-T-A-L-R-A-H-R-M-G-L-V-E-L-T-R-H-P-G-D-V-P-T-G-A-V-V-L-D-P-T-V-E-K-A-L-S-R-E-D-R-D-A-A-L-E-R-G-L-V-A-V-D-C-S-W-E-H-V-H-R-Y-F-G-P-L-R-R-R-C-R-H-R-I-L-P-Y-L-I-A-A-N-P-V-N-Y-G-K-P-C-K-L-S-T-V-E-A-L-A-A-A-L-Y-I-L-G-F-R-R-E-A-E-E-F-I-S-R-F-K-W-G-P-A-F-L-E-L-N-R-E-R-L-E-A-Y-R-R-A-E-T-S-A-E-V-V-R-V-Q-E-E-F-L-P-D-G-L"} +{"text": "### FUNCTION Guanylyltransferase that catalyzes the activation of -lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor ### SEQUENCE -M-R-F-V-V-P-F-A-D-R-G-D-R-K-T-R-L-S-S-C-M-D-E-E-T-R-E-R-F-A-L-A-M-L-R-H-V-V-R-V-L-S-K-F-G-E-V-E-V-V-T-P-D-S-S-L-S-V-P-G-T-K-V-R-R-S-D-A-S-L-D-E-L-P-L-P-D-G-E-F-G-L-V-M-S-D-L-P-L-L-S-E-E-D-V-E-R-A-L-E-G-L-K-D-A-D-V-V-L-C-P-S-R-R-G-G-T-S-G-V-F-V-R-K-G-V-R-F-R-P-T-F-G-G-V-S-F-P-R-N-L-R-R-A-E-K-Q-G-V-E-V-A-V-V-K-S-L-G-F-F-A-D-V-D-E-P-E-D-L-L-D-A-A-L-L-G-R-R-E-V-A-K-I-A-R-S-V-V-E-V"} +{"text": "### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-T-A-G-G-R-R-M-S-M-V-D-V-T-G-K-K-E-E-I-R-I-A-E-A-S-G-F-L-R-L-T-E-D-G-V-N-A-V-K-S-G-E-S-H-P-Q-G-K-G-D-P-I-E-V-A-K-V-A-A-I-L-A-V-K-K-T-P-E-L-V-P-H-C-H-P-I-K-I-T-G-V-D-V-D-V-E-V-L-E-D-G-V-K-M-S-V-R-V-K-S-E-G-K-T-G-V-E-M-D-A-L-T-G-L-V-V-G-L-V-T-L-W-D-M-V-K-Y-A-E-K-D-E-E-G-Q-Y-P-H-T-R-I-E-N-V-R-V-V-E-K-I-I-K-E-K-E"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA to 40 S ribosomal subunits ### SEQUENCE -M-G-K-R-I-D-D-E-T-L-K-K-I-R-L-P-K-E-G-E-I-F-G-V-V-E-K-M-L-G-N-D-R-V-Q-V-R-C-V-D-G-K-T-R-V-A-R-I-P-G-K-M-R-K-R-V-W-I-R-E-G-D-V-V-L-V-K-P-W-E-F-Q-P-E-R-A-D-V-T-W-R-Y-T-R-V-Q-V-D-W-L-K-R-K-G-K-L-D-E-R-V-T-K-L-L-E-E-I-I-P-G-A"} +{"text": "### FUNCTION Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein and RNA polymerase recruitment Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes ### SEQUENCE -M-Y-A-E-L-G-E-E-D-L-E-V-L-R-D-V-T-L-S-L-L-D-S-E-K-G-V-D-P-E-V-A-K-R-T-V-D-V-I-L-K-R-E-A-I-D-E-E-I-A-E-E-L-G-V-D-P-R-E-V-R-K-V-L-Y-K-L-H-E-R-G-V-V-T-F-R-K-E-R-R-E-E-Y-R-Y-P-V-Y-S-W-R-L-N-L-R-E-V-L-R-R-C-L-E-E-R-R-R-E-L-E-E-V-E-R-A-L-S-N-D-M-S-H-P-M-F-H-C-G-N-D-D-C-P-R-M-S-F-E-E-A-M-E-H-E-F-R-C-P-K-C-G-E-V-L-E-E-V-D-L-T-E-E-R-R-E-L-E-R-L-A-E-E-L-K-V-E-I-R-R-L-E-E-L-R-E-R-L-G"} +{"text": "### FUNCTION One of the integral membrane subunits of multisubunit membrane-bound -hydrogenase eha Eha is predicted to form large electron transfer complex and might catalyze energy-driven reduction of low-potential redox carriers ### SEQUENCE -M-K-D-P-G-L-V-A-V-G-V-A-A-A-V-A-F-G-T-A-L-A-L-G-L-P-P-I-Q-R-D-K-P-R-R-K-S-W-E-V-S-A-A-F-P-T-P-V-I-A-A-G-A-T-V-L-V-I-R-V-I-G-Y-H-P-P-I-P-L-A-I-V-G-A-V-V-G-A-L-S-A-A-F-T-A-Y-I-E-K-V-F-P-R-P-E-A-G"} +{"text": "### FUNCTION Involved in ribosome biogenesis ### SEQUENCE -M-P-K-R-L-R-R-C-K-E-C-G-E-Y-T-L-Q-R-D-K-C-P-H-C-G-G-D-L-E-V-P-H-P-H-R-F-S-P-E-D-P-Y-G-K-Y-R-R-K-L-K-K-R-V-W-A-E-K-F-G-P-P-S-G-E-G-D"} +{"text": "### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-A-K-R-Y-G-P-K-I-E-D-P-H-D-V-L-L-Y-P-V-A-T-E-K-A-M-R-L-M-E-A-E-N-K-L-T-F-I-V-R-R-D-A-N-K-P-L-I-K-K-A-V-E-E-L-F-D-V-E-V-E-K-V-N-T-L-I-T-P-T-G-E-K-K-A-Y-V-K-L-K-P-E-Y-R-A-E-D-V-A-V-D-L-G-I-L"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-R-V-R-L-S-S-A-L-R-P-R-W-R-Y-V-T-F-K-V-W-S-E-R-V-E-A-L-D-F-G-G-M-K-D-L-V-V-R-A-L-L-S-V-L-G-P-T-G-T-G-R-I-G-P-W-L-V-R-S-Y-R-D-L-N-A-G-I-L-R-V-R-R-G-Q-E-E-E-A-R-A-A-L-S-L-Y-R-R-D-P-K-L-G-R-V-F-I-E-V-L-G-T-S-G-T-I-K-G-A-E-R-Y-L-S-R-I-P-K-W-D-R-E-R-V-G-N-R-E-F-V-L-Y-E-N-G-E-V-D-V-V-E-D-G-R-I-V-A-F-A-S-F-E-C-P-L-P-E-E-N-R-G"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-A-Q-N-V-E-Q-Q-V-A-Q-L-Q-Q-L-Q-Q-Q-L-S-S-I-V-A-Q-K-Q-Q-L-E-L-Q-L-R-E-I-E-R-A-L-K-E-L-D-E-I-E-E-D-T-K-V-Y-K-T-V-G-G-L-L-I-E-A-D-R-D-E-V-K-E-E-L-E-D-R-K-E-T-L-E-L-R-V-K-T-L-E-K-Q-E-K-R-L-Q-Q-Q-I-E-N-L-Q-K-R-L-Q-K-A-L-Q-Q-A-E-G-G-G-G-A-G-A-A"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-S-E-I-R-L-G-L-V-V-T-E-F-N-R-E-I-T-Y-A-M-E-E-L-A-V-Q-H-A-K-D-L-G-A-K-V-V-E-R-V-L-V-P-G-S-F-E-V-P-L-A-V-R-K-L-L-E-R-D-D-I-D-A-V-V-T-L-G-A-I-I-K-G-D-T-D-H-D-Q-A-I-A-Q-Q-A-F-R-K-I-Q-D-L-M-V-E-Y-G-K-P-V-A-L-G-I-S-G-P-G-M-T-R-M-E-A-L-E-R-V-H-Y-A-K-R-A-V-E-A-A-V-K-M-V-R-R-L-R-E-L-E-G-E"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-I-V-V-S-K-V-L-V-D-L-K-V-L-P-E-S-A-D-V-D-Y-E-E-L-K-E-A-I-R-E-K-L-E-S-M-D-V-V-D-I-E-G-M-E-E-E-P-I-A-F-G-L-K-A-I-R-V-K-V-V-V-P-D-A-E-G-G-T-D-A-L-E-D-A-L-K-E-V-D-E-V-N-Q-V-E-V-V-S-A-S-R-T-L"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-Q-E-V-R-L-R-L-S-S-T-D-H-Y-K-L-E-E-V-C-E-R-I-K-K-V-V-E-E-T-G-A-Q-M-S-G-P-I-P-L-P-T-K-R-L-L-V-P-T-R-K-S-P-D-G-E-G-K-A-T-W-D-K-W-E-M-R-I-H-K-R-L-I-D-I-K-G-D-E-R-T-I-R-R-L-M-R-I-H-I-P-E-E-V-H-V-E-I-I-M-K"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently ### SEQUENCE -M-P-W-E-E-I-E-H-T-A-D-A-A-F-R-V-W-A-D-T-P-E-D-L-L-V-E-A-A-K-A-L-F-D-L-I-T-D-L-D-A-V-E-P-E-E-E-V-E-I-E-A-E-G-G-D-L-V-E-L-L-H-D-W-L-E-E-I-H-F-R-H-E-I-D-G-M-L-F-S-D-F-E-V-K-E-L-K-K-E-E-G-W-K-V-R-G-V-A-R-G-E-P-Y-D-P-D-R-H-P-F-H-T-E-V-K-A-V-T-Y-H-N-M-K-V-E-R-E-D-G-R-W-V-A-E-Y-V-V-D-L"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-K-G-T-P-S-F-G-K-R-N-K-T-K-T-H-V-R-C-R-R-C-G-R-R-A-Y-H-V-R-K-G-Y-C-A-A-C-G-F-G-R-S-R-R-I-R-R-Y-S-W-Q-N-K-K-V-N-R-K-R-R-R"} +{"text": "### FUNCTION Involved in protein export The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex ### SEQUENCE -M-G-K-K-M-E-K-K-R-A-E-M-P-P-A-R-A-G-I-L-S-F-W-D-E-E-A-P-G-I-K-I-D-P-D-Y-I-L-Y-A-C-F-A-V-A-V-L-L-I-I-A-H-T-M-A-A-V"} +{"text": "### FUNCTION Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP ### SEQUENCE -M-Y-V-G-R-F-L-L-A-G-K-L-E-D-G-T-P-I-A-V-Y-G-V-C-S-R-S-F-S-D-R-R-I-E-V-R-E-G-A-A-F-V-V-P-E-D-P-S-Y-I-T-E-N-P-Y-V-T-Y-T-C-A-R-I-V-D-E-F-L-V-L-T-N-G-A-Q-T-D-P-I-A-D-K-L-E-S-G-V-P-P-R-E-A-L-V-S-V-T-F-A-M-D-Y-E-H-D-E-Y-N-T-P-R-I-S-L-I-T-D-G-E-T-F-W-L-G-R-V-A-P-E-E-V-Y-F-R-V-M-K-P-K-D-G-E-G-Y-L-L-S-V-Y-G-E-Y-A-E-V-P-S-K-P-N-M-T-L-D-R-E-D-P-L-E-C-D-P-V-P-S-F-E-H-Y-V-C-S-V-I-A-R-H-D-G-G-R-W-S-L-E-A-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-V-V-R-R-K-K-K-S-P-K-K-Y-R-G-S-R-T-H-G-G-G-S-H-K-N-R-R-G-A-G-N-R-G-G-R-G-M-A-G-S-H-K-H-K-W-F-H-V-I-K-Y-M-P-D-H-F-G-K-R-G-F-N-R-P-P-K-V-V-R-E-P-N-T-I-N-V-G-E-L-D-A-L-A-D-K-L-L-E-D-G-I-A-E-K-D-G-D-K-I-V-I-D-V-T-D-E-R-L-K-P-Y-G-G-P-F-D-K-V-L-G-G-G-H-V-K-R-P-L-V-V-V-A-P-E-F-T-E-R-A-V-E-K-L-E-E-A-G-G-E-A-R-E-A"} +{"text": "### FUNCTION Involved in protein export The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex ### SEQUENCE -M-A-K-E-K-T-T-L-P-P-T-G-A-G-L-M-R-F-F-D-E-D-T-K-A-V-K-V-T-P-K-G-A-L-A-I-V-L-V-F-I-L-I-E-V-L-L-Q-I-I-G-P-R-I-F-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-P-K-Q-V-V-E-V-L-V-E-G-G-K-A-T-P-G-P-P-L-G-P-A-I-G-P-L-G-L-N-V-K-Q-V-V-D-K-I-N-E-A-T-K-D-F-A-G-M-Q-V-P-V-K-I-I-V-D-P-V-T-K-Q-F-E-I-E-V-G-V-P-P-T-S-Q-L-I-K-K-E-L-G-L-E-K-G-S-G-E-P-K-H-N-I-V-G-N-L-T-M-E-Q-V-I-K-I-A-K-M-K-K-D-Q-M-L-A-L-T-L-K-A-A-A-K-E-V-I-G-T-A-L-S-M-G-V-T-V-E-G-K-D-P-R-E-V-Q-K-E-I-D-E-G-V-Y-D-E-L-F-E-K-A-E-K-E"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-G-D-F-N-L-V-G-V-I-R-V-M-P-T-D-P-E-V-N-L-D-E-L-E-E-K-L-K-A-L-I-P-E-K-Y-G-L-A-K-V-E-R-E-P-I-A-F-G-L-V-A-L-K-F-Y-V-L-G-R-D-E-E-G-Y-S-F-D-E-I-A-E-K-F-Q-E-V-E-E-V-E-S-A-E-V-E-T-V-S-R-I"} +{"text": "### FUNCTION Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP ### SEQUENCE -M-G-R-F-V-V-W-P-S-E-L-D-S-R-L-S-R-K-Y-G-R-I-V-P-R-S-I-A-V-E-S-P-R-V-E-E-I-V-R-A-A-E-E-L-K-F-K-V-I-R-V-E-E-D-K-L-N-P-R-L-S-G-I-D-E-E-L-R-T-F-G-M-I-V-L-E-S-P-Y-G-K-S-K-S-L-K-L-I-A-Q-K-I-R-E-F-R-R-R-S-A"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-A-E-E-H-V-V-Y-I-G-K-K-P-V-M-N-Y-V-L-A-V-I-T-Q-F-N-E-G-A-K-E-V-S-I-K-A-R-G-R-A-I-S-R-A-V-D-V-A-E-I-V-R-N-R-F-L-K-D-T-V-D-I-K-E-I-K-I-G-T-E-E-L-P-T-A-D-G-R-T-T-N-T-S-T-I-E-I-V-L-E-R-K-V"} +{"text": "### FUNCTION Probable zinc metalloprotease whose natural substrate is unknown ### SEQUENCE -M-R-D-M-I-I-V-V-P-I-G-E-V-P-S-D-V-L-S-F-L-S-E-N-I-E-S-F-Y-M-K-F-G-I-G-V-K-I-I-G-S-L-P-I-S-A-F-S-H-A-Y-D-F-Y-R-N-Q-Y-L-A-R-H-F-L-P-A-L-S-I-I-R-R-D-Y-K-A-L-A-V-M-G-V-T-E-V-D-L-Y-E-S-G-L-N-F-I-F-G-I-A-H-P-G-F-G-V-A-L-I-S-L-H-R-L-Y-P-E-F-Y-G-E-P-P-D-R-K-L-L-K-E-R-A-L-K-E-A-M-H-E-L-G-H-V-F-G-L-E-H-C-P-N-P-K-C-V-M-H-F-S-N-S-I-I-D-T-D-I-K-S-W-M-Y-C-K-N-C-L-R-K-L-E-E-R-L-G-R-G-Y-V-R-G-R-T"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-K-E-F-R-Y-R-G-Y-T-L-E-Q-L-M-N-M-S-L-E-E-L-A-R-L-F-P-A-R-Q-R-R-S-L-K-R-G-L-T-P-E-Q-K-K-L-L-R-K-I-R-L-A-K-K-G-K-Y-K-K-P-I-R-T-H-C-R-D-M-I-I-L-P-E-M-V-G-L-T-I-Y-V-H-N-G-K-E-F-V-P-V-E-I-K-P-E-M-I-G-H-Y-L-G-E-F-A-P-T-R-K-K-V-E-H-G-A-P-G-V-G-A-T-R-S-S-M-F-V-A-V-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-A-K-R-F-G-Y-S-F-Q-N-F-D-P-K-R-M-A-R-A-S-A-R-D-L-R-I-S-P-K-L-A-V-E-V-C-R-E-L-R-G-M-M-L-N-D-A-L-R-Y-L-D-D-V-I-A-L-K-R-P-V-P-L-K-R-Y-N-D-S-Q-G-H-K-P-G-K-G-F-G-P-G-R-Y-P-V-K-V-A-K-A-I-K-K-V-L-L-N-V-K-N-N-A-V-Q-K-G-L-D-P-D-K-L-K-I-I-H-I-A-A-H-K-G-P-V-L-R-G-W-Y-P-R-A-F-G-R-A-T-P-F-N-E-Q-T-T-H-I-E-V-V-V-E-E-I-R-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-M-R-D-I-G-L-R-V-Q-P-P-A-E-K-C-D-D-P-K-C-P-W-H-G-N-L-K-I-H-G-R-V-F-E-G-I-V-V-S-D-K-P-R-K-T-V-T-V-E-R-Q-Y-Y-F-Y-L-N-K-Y-E-R-Y-E-L-R-R-S-K-I-H-A-H-N-P-P-C-I-N-A-K-V-G-D-K-V-L-I-A-E-T-R-P-L-S-K-T-K-H-F-V-V-V-A-V-L-E-R-A-E-E-R-R"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-A-K-K-G-A-G-A-T-R-G-V-S-A-V-R-P-T-R-A-L-P-V-G-A-Y-L-T-V-A-D-N-S-G-A-K-V-I-Q-I-I-G-V-V-E-Y-H-G-T-R-R-R-L-A-S-A-G-V-G-D-M-V-V-A-T-V-K-K-G-R-P-D-M-R-H-Q-V-V-R-A-V-I-I-R-Q-R-K-E-Y-R-R-L-D-G-M-R-V-K-F-E-D-N-A-A-V-I-V-T-P-E-G-V-P-R-G-T-E-I-R-G-P-V-A-R-E-A-A-E-R-W-V-R-I-G-S-I-A-S-I-I-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-L-L-D-P-L-A-N-A-L-S-H-I-T-N-S-E-R-V-G-K-R-E-V-Y-I-K-P-A-S-K-L-I-G-E-V-L-R-V-M-Q-K-Y-G-Y-I-G-E-F-E-F-I-D-D-G-R-A-G-V-Y-R-V-Q-L-L-G-R-I-N-K-A-G-A-I-K-P-R-F-P-V-K-V-S-E-F-E-K-W-E-K-R-F-L-P-A-F-E-F-G-I-L-I-V-S-T-S-Q-G-V-M-S-H-K-E-A-I-E-K-G-I-G-G-R-L-I-A-Y-V-Y"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-P-V-D-A-W-I-R-E-E-V-E-I-P-E-G-V-E-V-T-V-E-G-Y-K-V-K-V-K-G-P-K-G-E-L-E-R-E-F-F-W-P-G-I-Q-I-F-T-E-D-G-N-V-V-I-Y-K-D-F-P-R-R-K-D-V-A-I-A-R-T-F-A-A-H-I-R-N-M-I-K-G-V-T-E-G-F-T-Y-K-L-K-V-V-Y-S-H-F-P-I-S-V-K-V-Q-G-D-E-V-I-I-E-N-F-L-G-E-K-A-P-R-K-A-K-I-L-P-G-V-T-V-K-V-R-G-Q-E-I-I-V-E-G-I-D-K-E-A-V-G-Q-T-A-A-N-I-E-Q-A-T-R-I-T-K-W-D-R-R-I-F-Q-D-G-I-Y-I-V-E-K-A-G-K-P-I-T-F"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-I-T-R-G-R-V-W-K-F-G-D-N-I-S-T-D-A-I-T-P-G-R-Y-N-L-T-K-D-P-N-E-L-A-K-I-A-F-I-E-E-R-P-E-F-S-K-E-V-K-P-G-D-V-V-V-G-G-K-N-F-G-I-G-S-S-R-E-S-A-A-L-A-L-K-A-A-G-V-G-G-V-I-A-K-S-F-G-R-I-F-F-R-N-A-V-N-L-G-L-P-L-L-I-G-N-T-D-P-L-L-D-G-E-I-V-E-V-N-W-R-S-G-E-V-K-K-E-D-G-E-V-L-K-F-K-P-L-D-S-F-L-L-A-I-V-E-E-G-G-I-I-E-Y-I-R-R-R-G-D-L-W-I-Q"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-N-F-R-H-I-V-R-V-A-G-V-D-L-D-G-N-K-Q-L-R-W-A-L-T-A-I-K-G-I-G-I-N-F-A-T-M-V-C-R-V-A-G-L-D-P-F-M-K-A-G-Y-L-T-D-E-Q-V-K-K-I-E-E-I-L-A-D-P-V-A-H-G-I-P-R-W-A-V-N-R-P-K-D-Y-E-T-G-R-D-L-H-L-I-T-A-K-L-D-M-A-I-R-E-D-I-M-R-L-R-R-I-R-A-Y-R-G-I-R-H-E-L-G-L-P-V-R-G-Q-R-T-R-S-N-F-R-R-G-Q-T-V-G-V-S-R-K-K-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-I-I-N-A-E-G-L-I-L-G-R-L-A-S-K-V-A-K-M-L-L-E-G-E-E-V-V-I-V-N-A-E-K-A-V-I-T-G-N-R-D-V-I-F-K-K-Y-K-Q-R-T-E-L-R-T-L-T-N-P-R-R-G-P-F-Y-P-K-R-S-D-E-I-V-R-R-T-I-R-G-M-L-P-W-K-T-D-R-G-R-K-A-F-K-R-L-K-V-Y-V-G-I-P-K-E-F-Q-G-K-E-L-E-T-I-I-E-A-H-V-S-R-L-S-R-P-K-Y-V-T-V-G-E-V-A-K-F-L-G-G-K-F"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA to 40 S ribosomal subunits ### SEQUENCE -M-L-M-P-K-K-E-R-K-V-E-G-E-E-V-I-R-V-P-L-P-E-G-N-Q-L-F-G-V-V-E-Q-A-L-G-A-G-W-M-D-V-R-C-E-D-G-K-V-R-R-C-R-I-P-G-R-L-R-R-R-V-W-I-K-V-G-D-L-V-I-V-E-P-W-P-V-Q-S-D-K-R-G-D-I-V-Y-R-Y-T-Q-T-Q-V-E-W-L-L-R-K-G-K-I-S-Q-E-F-L-T-G-G-S-L-L-L-E"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-G-F-R-Y-K-Q-V-I-V-A-R-S-D-L-K-L-S-K-G-K-L-A-V-Q-V-A-H-G-A-V-T-A-A-F-E-A-Y-K-K-K-R-E-W-F-E-A-W-F-R-E-G-Q-K-K-V-V-V-K-A-Q-N-E-E-E-L-F-K-L-K-S-E-A-E-K-L-G-L-P-T-A-L-I-R-D-A-G-L-T-E-I-P-P-G-T-I-T-V-L-A-I-G-P-G-P-E-E-V-V-D-K-V-T-G-H-L-K-L-L"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently ### SEQUENCE -M-R-Q-W-E-H-Y-E-H-T-A-D-I-G-I-R-G-Y-G-D-T-L-E-E-A-F-E-A-V-A-L-A-L-F-D-V-I-V-N-V-R-K-I-E-K-K-V-E-I-D-I-E-V-E-G-E-D-L-E-S-L-L-Y-S-F-L-E-E-L-L-Y-L-H-D-I-E-G-L-V-F-G-D-F-K-V-K-I-E-Q-K-D-G-K-Y-I-L-R-G-K-A-Y-G-E-K-F-D-P-E-K-H-E-P-K-E-E-V-K-A-I-T-Y-H-D-M-K-I-E-R-L-P-D-G-R-W-M-A-Q-L-V-P-D-I"} +{"text": "### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-M-P-M-N-P-K-Q-L-K-K-L-M-K-Q-L-D-M-R-Q-L-D-N-V-V-E-V-I-I-R-L-E-D-R-E-I-I-I-K-N-P-T-V-T-V-I-K-A-M-G-E-K-I-Y-Q-I-A-G-G-E-E-E-E-K-V-K-L-V-I-S-E-E-D-I-K-L-V-M-E-Q-T-G-V-D-Y-E-T-A-K-K-A-L-E-E-A-N-G-D-L-A-E-A-I-L-K-L-T-E-G-S-P"} +{"text": "### FUNCTION DNA-binding protein involved in the repression of transcription of a large number of genes, thereby arresting growth, in response to environmental changes ### SEQUENCE -M-R-G-I-L-D-D-I-D-K-K-I-I-E-I-L-Q-K-D-G-K-V-P-L-R-E-I-S-K-I-T-G-L-A-E-S-T-I-H-E-R-I-K-R-L-R-E-S-G-V-I-K-K-F-T-A-V-V-N-P-E-A-L-G-Y-N-I-L-A-F-I-L-I-K-V-K-A-G-K-Y-S-E-V-A-S-K-L-V-K-Y-P-E-I-V-E-V-Y-E-T-T-G-D-Y-D-M-V-V-K-I-R-T-K-N-S-E-E-L-N-N-F-L-D-M-V-G-S-I-E-G-V-E-G-T-H-T-M-I-V-L-K-V-H-K-E-T-T-E-L-P-V-K"} +{"text": "### FUNCTION Catalyzes the synthesis of GMP from XMP ### SEQUENCE -M-I-I-I-M-D-N-G-G-Q-Y-V-H-R-I-W-R-T-L-R-Y-L-G-V-E-A-K-I-I-P-N-T-T-P-L-D-E-I-K-A-M-K-P-K-G-I-I-F-S-G-G-P-S-L-E-N-T-G-N-C-E-K-I-L-E-H-Y-E-E-F-N-V-P-I-L-G-I-C-L-G-H-Q-L-I-A-K-F-F-G-G-E-V-G-R-G-E-K-A-E-Y-S-L-V-E-I-E-I-I-D-E-N-D-I-F-K-G-L-P-R-K-V-R-V-W-E-S-H-M-D-E-V-K-K-L-P-P-K-F-K-L-L-A-R-S-D-T-C-P-V-E-A-M-K-H-E-E-L-P-I-Y-G-V-Q-F-H-P-E-V-A-H-T-E-H-G-A-D-I-L-R-N-F-A-K-I-C-G-E-L"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-I-E-V-G-E-Y-K-I-K-E-G-L-Y-Y-T-K-E-H-E-W-V-Q-V-L-E-D-G-T-V-L-V-G-I-T-D-Y-A-Q-K-E-L-G-D-L-A-Y-V-E-L-P-E-V-G-K-V-V-E-K-G-D-V-L-C-E-V-E-S-V-K-A-V-S-E-V-Y-A-P-V-S-G-E-V-I-E-V-N-E-E-L-A-D-S-P-E-K-I-N-E-D-P-Y-E-A-W-I-A-K-I-K-P-K-N-L-E-E-E-L-K-E-L-M-D-A-K-A-Y-A-E-Y-L-K-T-L"} +{"text": "### FUNCTION Functions by promoting the formation of the first peptide bond ### SEQUENCE -M-G-D-K-T-K-V-Q-V-S-K-L-K-P-G-R-Y-I-I-I-D-D-E-P-C-R-I-V-N-I-T-V-S-S-P-G-K-H-G-S-A-K-A-R-I-E-A-V-G-I-F-D-G-K-V-R-S-I-V-K-P-T-S-A-E-V-D-V-P-I-I-D-K-R-T-A-Q-V-I-A-V-T-P-D-T-V-Q-I-M-D-M-E-T-Y-E-M-F-E-V-P-L-D-T-G-V-E-E-E-I-K-D-K-I-K-E-G-I-N-V-E-Y-W-E-T-L-G-R-I-K-I-M-R-I-K-G-E-E-E"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-D-L-R-E-V-A-L-V-L-I-G-G-G-T-G-A-V-A-R-Y-Y-L-S-G-V-L-P-V-Y-R-S-F-P-V-G-T-L-L-V-N-S-L-A-S-F-L-L-G-Y-L-Y-G-L-I-F-W-G-L-D-V-S-R-E-S-R-L-F-L-G-T-G-F-C-G-G-L-S-T-F-S-T-F-S-Y-E-T-F-S-L-I-R-E-G-E-Y-L-T-A-L-L-N-I-F-A-N-V-L-A-T-I-F-L-V-F-L-G-F-V-L-A-R-R"} +{"text": "### FUNCTION Involved in ribosome biogenesis ### SEQUENCE -M-R-F-R-I-R-K-C-P-K-C-G-R-Y-T-L-K-E-V-C-P-V-C-G-E-K-T-K-V-A-H-P-P-R-F-S-P-E-D-P-Y-G-E-Y-R-R-R-W-K-R-E-V-L-G-I-G-R-K-E-K"} +{"text": "### FUNCTION Broad-specificity nucleoside monophosphate kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-I-I-A-I-T-G-T-P-G-V-G-K-T-T-V-A-R-K-L-A-E-K-L-G-C-K-Y-V-N-L-R-D-F-A-L-E-K-G-I-G-E-V-K-G-D-E-L-E-V-E-V-D-E-L-A-Y-F-V-E-K-E-F-K-G-K-N-V-V-L-D-G-H-L-S-H-L-M-P-A-D-L-V-I-V-L-R-A-H-P-K-T-I-A-E-R-L-K-E-R-G-Y-S-K-D-K-I-G-E-N-V-E-A-E-L-V-D-V-I-L-I-E-A-L-D-E-H-E-N-V-I-E-V-D-T-T-G-K-T-P-E-E-V-V-N-E-I-L-N-L-I-N-S-G-I-K-R-R-V-G-I-V-D-W-T-K-V-Y-E-E-I-I-P-Y-L-R-L-G-G-D"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-Y-I-V-V-V-Y-D-V-G-V-E-R-V-N-K-V-K-K-F-L-R-M-H-L-N-W-V-Q-N-S-V-F-E-G-E-V-T-L-A-E-F-E-R-I-K-E-G-L-K-K-I-I-D-E-N-S-D-S-V-I-I-Y-K-L-R-S-M-P-P-R-E-T-L-G-I-E-K-N-P-I-E-E-I-I"} +{"text": "### FUNCTION S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 ### SEQUENCE -M-Q-F-S-E-N-F-E-R-A-K-K-E-A-L-I-S-L-E-I-A-L-R-K-G-E-V-D-E-D-I-I-P-L-L-K-K-I-N-S-L-D-N-Y-F-T-T-S-S-C-S-G-R-I-S-V-M-E-M-P-H-F-G-D-K-V-N-A-K-W-L-G-K-W-H-R-E-V-S-L-D-E-V-L-G-A-I-K-K-H-R-S-G-Q-L-W-F-L-V-R-S-P-I-L-H-V-G-A-K-T-L-E-D-A-I-R-L-V-N-L-A-V-S-C-G-F-K-Y-S-N-I-K-S-I-S-N-K-K-L-I-V-E-I-R-S-T-E-R-M-D-V-L-L-G-E-N-G-R-I-L-V-G-E-E-Y-L-R-K-I-V-E-I-A-N-A-Q-V-R-R-F-K-E-K-L-K-R-L-E-S-N-I-D-A-L-N-R"} +{"text": "### FUNCTION Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA and pyrophosphate ### SEQUENCE -M-K-K-K-Y-K-K-V-V-V-G-G-T-F-D-R-L-H-L-G-H-K-A-L-L-R-K-A-F-E-V-G-E-I-V-Y-I-G-L-T-S-D-E-M-I-K-E-K-Q-Y-S-E-R-I-L-P-Y-E-K-R-L-L-D-L-I-K-F-L-E-V-N-K-Y-R-N-Y-R-I-M-K-I-H-N-A-I-G-F-T-T-K-I-K-S-L-E-A-I-V-V-S-E-E-T-Y-K-G-A-V-L-V-N-K-A-R-E-E-L-G-L-R-P-L-D-I-V-V-I-P-I-I-R-S-R-L-G-C-K-I-S-S-S-L-I-R-A-G-L-I-D-P-F-G-N-P-I-R-R-E-E-K"} +{"text": "### FUNCTION Functions as a protein modifier covalently attached to lysine residues of substrate proteins, as well as a sulfur carrier in tRNA thiolation The protein modification process is termed sampylation and involves the formation of an isopeptide bond between the SAMP2 C-terminal glycine carboxylate and the epsilon-amino group of lysine residues on target proteins Is able to form polymeric chains with itself likely at Lys-55, similar to ubiquitin and other ubiquitin-like proteins May serve as a proteolytic signal in the cell to target proteins for degradation by proteasomes ### SEQUENCE -M-K-M-I-K-V-K-V-I-G-R-N-I-E-K-E-I-E-W-R-E-G-M-K-V-R-D-I-L-R-A-V-G-F-N-T-E-S-A-I-A-K-V-N-G-K-V-V-L-E-D-D-E-V-K-D-G-D-F-V-E-V-I-P-V-V-S-G-G"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-K-A-R-G-R-A-W-K-Y-G-D-N-I-D-T-D-V-I-I-P-A-R-Y-L-N-T-S-D-P-K-E-L-A-Q-H-V-L-E-D-L-D-P-E-F-R-Y-K-M-K-P-G-D-I-I-V-A-G-E-N-F-G-C-G-S-S-R-E-H-A-P-L-A-I-K-A-A-G-V-S-A-V-I-A-K-S-F-A-R-I-F-Y-R-N-A-I-N-I-G-L-P-I-L-E-A-P-E-A-V-E-R-I-E-T-G-D-E-I-E-I-D-F-S-T-G-E-I-R-N-L-T-K-G-E-V-Y-H-A-N-P-F-P-E-F-I-M-E-I-I-K-A-G-G-L-V-E-W-A-K-R-R-L-A-K"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-W-A-L-A-D-A-I-V-R-T-V-L-D-Y-A-Q-K-E-G-A-S-R-V-K-A-V-K-V-V-L-G-E-L-Q-D-V-G-E-D-I-V-K-F-A-M-E-E-L-F-R-G-T-I-A-E-G-A-E-I-I-F-E-E-E-E-A-V-F-K-C-R-N-C-G-H-V-W-K-L-K-E-V-K-D-K-L-D-E-R-I-R-E-D-I-H-F-I-P-E-V-V-H-A-F-L-S-C-P-K-C-G-S-H-D-F-E-V-V-K-G-R-G-V-Y-I-S-G-I-M-I-E-K-E-G-E-E"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-A-E-L-K-V-S-A-I-K-E-G-T-V-I-D-H-I-P-A-G-K-G-L-K-V-I-Q-I-L-G-L-G-E-L-K-N-G-G-A-V-L-L-A-M-N-V-P-S-K-K-L-G-R-K-D-I-V-K-V-E-G-K-F-L-S-E-E-E-V-N-K-I-A-L-V-A-P-T-A-T-V-N-I-I-R-E-Y-K-V-V-E-K-F-K-V-E-I-P-D-V-I-E-G-I-L-K-C-G-N-P-N-C-I-T-H-Y-E-Y-V-T-P-K-F-Y-V-I-S-K-E-P-L-K-V-R-C-H-Y-C-E-R-T-M-E-E-E-E-I-L-A-N-L"} +{"text": "### FUNCTION Putative transcriptional regulator ### SEQUENCE -M-K-T-F-L-T-E-Q-Q-I-K-V-L-M-L-R-A-K-G-Y-K-Q-S-E-I-A-K-I-L-G-T-S-R-A-N-V-S-I-L-E-K-R-A-M-E-K-I-E-K-A-R-N-T-L-L-L-W-E-Q-I-N-S-K-V-I-V-E-I-K-A-G-E-D-I-F-S-I-P-E-K-F-F-K-K-A-D-K-V-G-V-K-V-P-Y-S-T-A-E-I-I-T-F-L-V-E-H-A-P-V-E-D-R-L-A-K-R-D-F-V-L-F-L-D-S-K-N-K-L-R-I-G-D-C-L-V-I-E-E-I-K-E-D"} +{"text": "### FUNCTION eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA ### SEQUENCE -M-E-I-D-Y-Y-D-Y-E-K-L-L-E-K-A-Y-Q-E-L-P-E-N-V-K-H-H-K-S-R-F-E-V-P-G-A-L-V-T-I-E-G-N-K-T-I-I-E-N-F-K-D-I-A-D-A-L-N-R-D-P-Q-H-L-L-K-F-L-L-R-E-I-A-T-A-G-T-L-E-G-R-R-V-V-L-Q-G-R-F-T-P-Y-L-I-A-N-K-L-K-K-Y-I-K-E-Y-V-I-C-P-V-C-G-S-P-D-T-K-I-I-K-R-D-R-F-H-F-L-K-C-E-A-C-G-A-E-T-P-I-Q-H-L"} +{"text": "### FUNCTION Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs ### SEQUENCE -M-I-V-V-L-R-L-G-H-R-P-E-R-D-K-R-V-T-T-H-V-A-L-T-A-R-A-F-G-A-D-G-I-I-I-A-G-E-E-D-E-K-V-K-E-S-V-E-D-V-V-K-R-W-G-G-S-F-F-I-R-F-E-K-N-W-R-K-E-I-K-E-F-R-G-I-K-V-H-L-T-M-Y-G-L-H-V-D-D-I-I-E-D-I-K-A-K-F-R-E-G-N-D-I-M-V-I-V-G-A-E-K-V-P-R-E-V-Y-E-L-A-D-Y-N-V-A-I-G-N-Q-P-H-S-E-V-A-A-L-A-V-F-L-D-R-L-L-E-G-K-G-L-K-K-E-F-K-N-A-K-L-R-I-I-P-Q-E-R-G-K-K-V-V-E-V-E-S-S-A-E-Q-F-E-T-I-G-E-K-A-T-G-K-D-S"} +{"text": "### FUNCTION Catalyzes the formation of CDP-2,3-bis- and CTP This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-H-P-I-L-E-A-F-W-Y-I-L-P-A-Y-F-A-N-S-S-P-V-I-L-G-G-G-T-P-I-D-F-G-K-T-W-R-D-G-R-R-I-F-G-D-S-K-T-W-R-G-F-L-G-G-L-T-V-G-T-L-I-G-V-I-Q-Q-I-I-Y-P-Y-Y-P-S-L-S-L-A-F-K-V-S-F-L-L-A-L-G-A-L-V-G-D-L-I-G-S-F-I-K-R-R-L-N-L-P-P-G-Y-P-A-V-G-L-D-Q-W-G-F-L-I-S-A-L-C-F-A-Y-P-V-H-T-I-P-T-G-E-V-L-L-L-L-V-V-T-P-L-I-H-W-G-T-N-V-L-A-Y-K-M-K-W-K-S-V-P-W"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-Q-N-I-P-P-Q-V-Q-A-M-L-G-Q-L-E-S-Y-Q-Q-Q-L-Q-L-V-I-Q-Q-K-Q-K-V-Q-A-D-L-N-E-A-K-K-A-L-E-E-I-E-K-L-T-D-D-A-V-I-Y-K-T-V-G-T-L-I-V-K-T-T-K-E-K-A-L-Q-E-L-K-E-K-V-E-T-L-E-V-R-L-N-A-L-N-R-Q-E-Q-K-I-N-E-K-I-K-E-L-T-Q-K-I-Q-A-A-L-R-P-P-T-A-G"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-E-N-N-K-E-L-E-K-V-A-Y-E-Y-Q-V-V-Q-A-Q-A-Q-L-L-A-Q-N-L-E-L-L-S-L-A-Q-A-E-V-Q-T-V-K-E-T-L-E-N-L-M-K-I-E-D-E-N-P-E-I-L-V-P-I-G-A-G-S-F-L-K-G-K-I-V-D-K-N-N-A-I-I-S-V-G-S-G-Y-A-V-E-K-T-L-E-D-A-I-K-Y-L-D-E-R-I-K-E-Y-D-E-A-I-R-K-T-Q-E-A-L-N-E-L-Q-K-R-A-A-E-L-A-K-K-A-Q-E-I-Q-Q-K-Q-A-M-S-F-K-L-K-K"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system An RNase ### SEQUENCE -M-P-L-P-P-D-I-T-F-D-S-L-A-L-I-K-M-H-S-Q-S-M-K-K-I-L-E-I-T-L-A-K-F-T-V-N-L-S-I-V-T-V-Y-R-Y-L-T-V-R-A-Y-L-K-K-N-I-E-L-E-L-D-V-L-K-D-I-Y-N-I-V-P-L-N-E-E-I-A-I-K-A-A-Q-I-E-A-D-L-M-R-K-G-M-M-P-D-I-E-D-V-L-T-A-A-T-A-I-Y-T-K-S-L-L-I-T-D-D-S-K-R-Y-E-P-M-R-R-F-G-L-D-T-M-P-L-D-K-F-V-K-E-V-E-L-M-V-E-K-E-L-I"} +{"text": "### FUNCTION CRISPR Cmr4 is probably the subunit that cleaves target RNA Cmr complex does not cleave ssDNA complementary to the crRNA Cleavage of invading RNA is guided by the crRNA ### SEQUENCE -M-Y-E-A-I-F-D-L-E-A-I-T-P-L-F-M-R-G-A-D-A-R-S-P-E-F-S-S-A-S-V-K-G-V-M-R-W-W-F-R-A-L-A-G-G-Y-F-G-N-N-I-E-A-L-K-E-V-E-E-K-I-F-G-S-T-R-N-K-S-R-V-F-V-R-A-E-V-E-D-V-K-K-G-N-I-Y-R-Q-A-S-S-W-A-D-K-T-I-I-V-W-S-E-Y-V-D-Y-F-F-F-S-V-L-D-K-R-R-N-R-K-T-K-K-I-D-I-K-T-R-F-E-Y-F-D-V-G-S-K-F-S-I-S-L-S-S-T-D-E-R-Y-F-R-L-A-E-A-S-L-W-M-T-I-N-L-G-G-F-G-F-R-A-R-R-G-A-G-S-L-K-V-Q-M-L-R-E-M-L-L"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-G-I-V-R-F-G-V-S-I-P-K-E-L-L-E-K-F-D-G-I-I-E-E-M-G-Y-T-N-R-S-E-A-I-R-D-L-I-R-D-M-V-V-R-H-E-W-Q-L-G-D-E-E-V-A-G-T-I-T-I-V-Y-N-H-D-E-A-D-V-V-R-E-L-L-D-L-Q-H-E-Y-L-N-E-I-V-S-S-L-H-V-H-M-D-E-H-N-C-L-E-V-I-V-V-K-G-R-A-K-K-I-K-K-I-A-D-R-L-L-S-L-K-G-V-K-H-G-K-L-V-M-T-T-T-G-R-D-I-V"} +{"text": "### FUNCTION Endonuclease that removes tRNA introns Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp ### SEQUENCE -M-K-T-V-I-E-F-Y-L-S-G-D-R-V-Y-S-E-R-E-K-A-I-N-Q-L-H-I-N-R-G-Y-G-E-L-K-G-K-R-L-F-L-S-L-I-E-A-A-Y-L-L-E-K-G-W-I-K-V-L-D-G-E-R-E-L-S-F-Y-D-V-V-S-L-G-K-K-K-D-E-D-F-D-V-K-Y-L-V-Y-K-D-L-R-D-R-G-Y-I-V-K-S-A-L-K-F-G-S-H-Y-R-V-Y-R-K-G-A-E-H-S-D-W-L-V-W-V-V-R-E-S-Q-K-L-S-P-N-D-I-T-A-R-A-R-V-A-H-G-V-R-K-T-M-V-L-A-V-V-D-E-D-G-D-V-V-Y-Y-K-V-E-W-T-K-F"} +{"text": "### FUNCTION Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A ### SEQUENCE -M-S-V-M-F-K-L-P-L-N-L-R-Q-E-L-K-K-P-L-G-E-L-I-K-G-E-I-P-I-P-Y-L-K-L-K-E-I-V-N-S-N-T-L-I-T-V-G-D-V-V-T-E-N-S-L-K-V-G-L-R-P-R-L-A-I-Y-D-H-K-T-E-R-R-E-Y-K-P-E-I-G-D-K-G-V-L-L-T-V-K-N-P-P-G-T-I-T-L-H-L-L-K-T-I-K-K-A-Y-S-L-I-R-R-G-T-N-V-H-I-V-V-N-G-E-E-D-L-A-A-I-P-A-V-L-Y-A-P-L-G-S-F-V-V-Y-G-Q-P-R-E-G-I-V-L-I-K-V-T-S-E-C-K-R-R-C-A-E-I-M-R-N-M-E-V-V-R-N-G-D"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-K-I-V-V-M-G-D-S-D-T-V-V-G-F-R-L-A-G-V-H-E-A-Y-E-Y-D-E-S-L-E-S-V-E-R-A-R-N-K-L-R-E-L-L-E-R-D-D-V-G-I-I-L-I-T-E-R-L-A-Q-R-I-G-S-L-P-E-V-K-F-P-I-I-L-Q-I-P-D-K-F-G-S-I-Y-G-E-D-I-L-R-D-V-V-R-R-A-I-G-V-E-L-K-R"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-N-G-A-Q-V-I-I-Q-E-I-N-R-E-A-E-Q-K-I-K-Y-I-L-D-E-A-R-K-E-A-E-K-I-K-E-E-A-R-K-R-G-E-S-R-A-E-W-I-L-R-K-A-K-T-Q-A-E-L-E-K-Q-R-I-I-A-T-A-R-L-E-V-R-R-K-K-L-S-L-Q-E-E-Y-I-S-R-V-L-K-E-V-T-S-R-L-S-N-L-S-E-D-E-Y-L-E-T-V-L-A-L-L-K-E-A-L-K-E-L-D-V-K-E-I-R-V-H-S-N-E-K-T-L-A-L-I-S-S-R-I-E-E-I-R-R-E-L-G-D-V-S-I-E-I-G-S-P-I-Q-T-I-G-G-V-I-V-E-T-K-D-G-N-M-R-V-D-N-T-F-E-A-R-M-A-R-L-E-S-E-L-R-S-K-I-A-E-I-L-F-G"} +{"text": "### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate May function as an ADP-ribosylase ### SEQUENCE -M-V-G-G-D-R-R-F-K-V-S-K-L-M-A-Y-I-L-R-H-S-P-W-E-F-G-L-E-P-D-E-E-G-F-V-E-L-A-D-L-I-R-A-I-K-T-V-Y-P-W-V-T-E-E-F-I-K-E-I-V-E-K-D-S-K-G-R-Y-E-I-R-G-S-K-I-R-A-R-Y-G-H-S-Y-P-V-V-L-K-H-E-E-D-T-E-S-K-V-L-Y-H-G-T-I-R-E-N-L-K-G-I-L-K-E-G-I-K-P-M-K-R-Q-Y-V-H-L-S-L-S-Y-E-D-A-Y-Y-T-G-R-R-H-G-K-D-V-V-V-L-L-I-D-A-E-C-L-R-R-K-G-Y-K-I-L-K-A-G-K-R-V-R-I-V-K-H-V-P-V-E-C-I-S-E-I-L-D"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-V-R-T-F-E-G-D-Y-R-G-E-G-L-R-I-A-V-V-V-S-R-F-N-D-L-L-T-E-E-L-L-K-G-A-L-D-C-F-K-R-H-G-V-E-E-V-H-I-F-R-V-P-G-S-F-E-I-P-I-T-V-K-K-I-A-K-R-G-Y-D-A-I-L-A-L-G-V-L-I-K-G-E-T-R-H-F-E-L-V-A-S-Q-V-S-R-G-I-A-Q-V-S-L-E-E-G-I-P-V-I-F-G-I-V-P-A-E-D-E-I-Q-A-I-S-R-S-G-I-K-S-N-R-G-F-E-Y-A-L-T-T-I-E-M-A-N-L-F-R-K-L-G-E-N-N-E-R"} +{"text": "### FUNCTION Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester In vitro, ligates 5' and 3' half-tRNA molecules with 2',3'-cyclic phosphate and 5'-hydroxyl termini, respectively, to the product containing the 2'-5' phosphodiester linkage Ligase activity requires GTP, but GTP hydrolysis is not required for the reaction, which is reversible Ligase activity is weak compared to the phosphodiesterase activity ### SEQUENCE -M-R-A-F-I-A-I-D-V-S-E-S-V-R-D-A-L-V-R-A-Q-D-Y-I-G-S-K-E-A-K-I-K-F-V-E-R-E-N-F-H-I-T-L-K-F-L-G-E-I-T-E-E-Q-A-E-E-I-K-K-I-L-E-K-I-A-K-K-Y-K-K-H-E-V-N-V-R-G-I-G-V-F-P-N-P-N-Y-V-R-V-I-W-A-G-V-E-N-D-E-I-I-K-K-I-A-K-E-I-D-D-E-L-A-K-L-G-F-K-K-E-G-N-F-V-A-H-I-T-L-G-R-V-K-F-V-K-D-K-L-G-L-A-M-K-L-K-E-L-A-N-E-D-F-G-S-F-I-V-E-A-I-E-L-K-K-S-T-L-T-P-K-G-P-I-Y-E-T-L-A-R-F-E-L-S-E"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-E-F-D-G-E-A-Q-A-V-E-P-T-S-R-M-L-S-W-A-R-N-S-A-L-Y-R-L-Q-Q-R-M-M-T-E-K-Q-L-R-D-A-I-M-R-K-A-R-E-K-F-E-D-I-G-P-A-Q-V-K-A-L-G-E-F-A-V-T-F-A-Y-G-I-K-A-L-D-D-T-A-Y-A-E-I-T-V-R-S-G-Q-R-S-G-K-S-K-R-G-L-A-Q-K-L-Q-I-K-G-V-A-R-E-T-A-T-A-A-L-Q-E-T-N-D-L-V-A-A-V-I-F-A-R-K-R-A-F-G-P-Y-R-R-V-E-P-D-E-K-R-K-A-K-E-F-S-A-F-A-R-N-G-F-S-F-E-I-G-A-K-V-M-A-M-T-T-E-E-A-E-D-I-L-S-D-A-P-L"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-F-R-Q-F-R-P-A-L-V-L-I-L-A-T-T-A-I-T-G-L-A-Y-P-L-G-M-T-G-L-A-Q-A-L-F-P-V-Q-A-N-G-S-M-I-E-K-D-G-K-V-V-G-S-Q-L-I-G-Q-A-F-T-G-E-T-Y-F-H-G-R-P-S-A-A-G-D-G-Y-N-A-A-S-S-S-G-S-N-L-G-P-T-S-A-K-L-I-D-R-V-K-T-D-Y-E-A-A-K-A-E-N-P-A-A-E-V-P-A-D-L-V-T-A-S-G-S-G-L-D-P-H-V-S-P-E-A-A-Y-F-Q-V-P-R-V-A-K-A-R-G-M-D-E-T-A-L-R-A-L-V-D-R-H-V-E-A-P-E-L-G-F-M-G-E-P-V-V-N-I-L-A-L-N-M-A-L-D-A-A-G-S"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-D-I-H-P-A-Y-H-T-I-K-V-V-M-T-D-G-T-E-Y-E-T-R-S-T-W-G-S-E-G-A-V-M-N-L-E-I-D-P-K-S-H-P-A-W-T-G-G-N-Q-Q-L-M-D-R-G-G-R-V-S-K-F-N-K-R-F-G-G-L-G-L"} +{"text": "### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate May function as an ADP-ribosylase ### SEQUENCE -M-S-T-A-T-S-K-F-L-S-Y-V-L-R-H-A-P-E-S-I-G-L-V-L-D-S-Q-G-W-A-D-V-A-D-L-L-A-K-A-N-A-S-G-T-P-L-D-E-A-G-L-R-A-V-V-A-E-S-D-K-K-R-F-T-L-S-E-D-G-R-R-I-R-A-A-Q-G-H-S-V-K-V-D-L-G-Q-P-P-V-E-P-P-P-Q-L-F-H-G-T-A-T-R-F-L-E-P-I-L-R-E-G-L-R-P-G-E-R-Q-Q-V-H-L-S-A-D-R-T-T-A-L-A-V-G-Q-R-H-G-K-P-V-V-L-I-V-D-A-G-Q-M-F-A-D-G-C-R-F-Y-L-A-D-N-G-V-W-L-T-D-A-V-P-F-S-Y-L-T-V-S-A-D-S-S-A-E-N-D-R"} +{"text": "### FUNCTION Represses an operon that comprises at least itself and blh Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon ### SEQUENCE -M-V-T-E-T-P-L-E-K-P-L-D-I-G-E-I-P-L-P-A-M-E-K-R-A-T-E-V-A-I-L-L-K-T-L-A-H-P-A-R-L-M-L-A-C-T-L-A-Q-G-E-F-S-V-G-E-L-E-A-K-L-D-I-R-Q-P-T-L-S-Q-Q-L-G-V-L-R-E-A-G-I-V-D-T-R-R-E-A-K-Q-I-F-Y-R-L-A-E-D-K-A-A-R-L-I-E-A-L-Y-A-I-F-C-A-P-E-E-N-L"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-I-F-S-I-F-R-K-Q-K-S-A-P-L-A-R-E-R-L-Q-V-L-L-A-H-E-R-A-S-S-G-T-D-L-V-A-V-L-R-E-E-I-L-S-V-I-A-K-H-V-Q-I-D-N-D-R-V-H-V-K-M-D-R-D-E-H-V-S-I-L-E-I-D-V-E-I-P-L-G-A-H-L-R-A-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-I-K-T-G-G-K-Q-Y-R-V-A-A-D-A-V-L-T-I-E-K-L-E-A-E-A-G-A-T-V-E-F-T-E-V-L-V-I-G-E-G-A-D-A-Q-F-G-A-P-F-V-K-G-A-I-V-K-A-E-V-V-E-H-N-R-G-K-K-V-I-A-F-K-K-R-R-R-Q-N-S-K-R-S-R-G-H-R-Q-H-H-T-V-V-R-I-T-D-I-V-A-A"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-R-I-S-I-F-A-V-G-R-L-K-S-G-P-E-K-D-L-A-A-R-Y-I-E-R-L-A-K-T-G-P-A-I-G-L-E-F-S-R-V-I-E-V-G-E-S-R-A-S-N-A-E-T-R-K-R-E-E-A-A-M-L-E-K-H-L-A-D-G-A-V-L-V-L-L-D-E-R-G-K-A-L-D-S-P-A-F-A-S-L-F-G-D-L-R-D-S-G-K-R-D-L-V-I-A-I-G-G-A-D-G-L-D-S-A-L-Y-D-K-A-T-A-V-L-N-L-G-K-L-T-W-P-H-Q-I-V-R-I-L-I-A-E-Q-L-Y-R-A-V-T-I-L-S-G-H-P-Y-H-R-V"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-T-I-K-A-E-D-L-P-Y-R-P-C-A-G-I-M-V-L-N-A-Q-G-L-V-W-A-G-R-R-I-K-E-G-N-S-E-Y-D-G-S-P-Q-L-W-Q-M-P-Q-G-G-I-D-D-G-E-R-P-L-T-A-A-I-R-E-L-Y-E-E-T-G-M-K-T-V-T-L-L-A-E-A-S-D-W-I-H-Y-D-L-P-P-E-L-I-G-I-G-L-R-G-K-Y-R-G-Q-A-Q-R-W-F-A-F-R-F-E-G-D-E-S-E-I-Q-I-D-P-P-P-T-G-H-S-A-E-F-D-A-W-D-W-K-P-M-E-S-L-P-E-L-I-V-P-F-K-R-A-V-Y-E-K-V-V-A-E-F-Q-H-L-S-G-K"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-T-N-I-I-Q-Q-L-E-A-E-Q-A-A-K-I-E-A-K-R-T-L-P-E-F-S-P-G-D-T-L-R-V-N-V-R-V-T-E-G-N-R-T-R-V-Q-A-Y-E-G-V-C-I-A-R-S-G-G-G-L-S-E-S-F-T-V-R-K-I-S-Y-G-E-G-V-E-R-V-F-P-I-Y-S-P-L-V-E-G-V-E-I-V-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-D-R-R-G-K-A-A-R-I-V-E-N-T-G-T-R-A-R-K-L-N-E-S-E-R-Q-A-A-A-E-E-K-A-R-L-E-A-E-K-V-A-A-A-Q-A-L-A-A-E-K-A-A-A-E-A-A-E-A-K-A-A-E-E-A-A-K-A-A-E-A-T-A-E"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-A-K-L-E-N-P-I-L-M-A-K-I-G-G-A-Q-G-L-R-G-E-V-R-V-S-T-Y-T-D-D-P-M-A-L-G-D-Y-G-N-L-V-T-A-D-G-R-V-F-E-I-L-E-V-R-E-G-K-N-V-V-V-V-R-F-R-G-I-N-D-R-N-A-A-E-S-L-N-G-L-E-L-F-I-E-R-D-N-L-P-D-D-E-L-D-D-D-E-F-Y-Y-A-D-L-E-G-L-E-A-V-D-A-E-G-K-S-Y-G-A-V-S-A-V-Y-D-F-G-A-G-D-L-L-E-L-K-G-A-G-R-R-P-A-L-I-P-F-S-E-A-A-V-L-E-I-D-L-E-A-G-R-I-L-I-D-P-M-A-A-G-L-I-D-N-P-D-D-K-D-Q-N-G-M-S-P-F-G-K-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-D-S-F-K-F-D-L-V-S-P-E-R-L-L-V-S-E-T-V-T-E-V-V-I-P-A-T-L-G-E-M-T-V-L-A-N-H-A-P-T-M-T-T-I-K-P-G-L-V-T-V-K-F-A-S-G-E-T-H-K-Y-V-V-F-G-G-F-A-D-I-L-P-T-G-C-T-L-L-A-E-S-A-V-S-A-D-D-M-S-P-D-T-L-Q-K-R-I-D-A-A-K-A-E-I-Q-E-G-N-H-H-H-E-H-L-T-K-L-E-K-H-L-Y-E-L-T-N-L-H-E-V-L-V-A-A"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-L-R-V-T-S-Y-H-P-A-G-T-P-G-D-E-P-S-G-Y-V-T-L-A-H-D-Q-R-H-L-R-R-K-L-L-H-L-Q-N-D-E-M-V-M-L-D-L-K-E-A-V-L-F-A-H-G-D-L-L-V-V-E-N-G-D-L-I-E-V-R-A-A-D-E-K-L-F-E-I-K-A-K-D-R-L-H-L-I-E-L-A-W-H-L-G-N-R-H-L-A-A-Q-I-E-E-E-R-I-L-I-L-R-D-H-V-I-R-A-M-L-E-G-L-G-A-T-V-R-D-V-E-E-P-F-Q-P-A-R-G-A-Y-H-A-H-G-G-H-S-H-D-H-G-Q-G-H-H-H-H-D-H-G"} +{"text": "### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate -ureidoglycolate, generating urea and glyoxylate Involved in the utilization of allantoin as nitrogen source ### SEQUENCE -M-T-D-F-L-E-I-R-P-L-T-K-E-A-F-T-P-F-G-D-V-I-E-T-T-P-S-S-M-R-H-I-N-G-G-Q-T-E-R-H-H-A-L-S-A-P-E-A-A-G-E-G-A-R-I-I-L-N-I-F-R-G-Q-P-R-V-F-P-H-K-I-D-M-M-E-R-H-P-L-G-S-Q-S-F-S-P-L-S-G-R-P-F-L-V-V-V-A-Q-D-D-G-G-R-P-A-R-P-Q-V-F-L-A-R-G-D-Q-G-V-N-Y-R-R-N-V-W-H-Y-P-L-M-P-L-Q-A-V-S-D-F-L-V-A-D-R-E-G-P-G-N-N-L-E-E-Y-F-F-D-E-P-F-M-I-A-E-P-S-L"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-V-I-A-S-E-L-S-A-A-I-R-S-I-P-D-Y-P-K-P-G-I-I-F-R-D-I-T-T-L-L-G-N-P-R-A-F-R-R-A-V-D-E-L-V-Q-P-Y-A-G-T-K-I-D-K-I-A-G-M-E-A-R-G-F-I-L-G-G-A-V-A-H-Q-L-S-A-G-F-V-P-I-R-K-K-G-K-L-P-H-T-T-V-R-V-A-Y-S-L-E-Y-G-V-D-E-M-E-M-H-V-D-A-V-Q-P-G-E-K-V-I-L-V-D-D-L-I-A-T-G-G-T-A-E-G-A-V-K-L-L-R-Q-M-G-A-E-I-V-S-A-C-F-V-I-D-L-P-D-L-G-G-R-K-K-L-E-D-L-G-V-D-V-R-T-L-V-E-F-S-G-H"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-D-S-P-V-D-L-K-P-K-P-K-V-K-P-K-L-E-R-P-K-L-Y-K-V-M-L-L-N-D-D-Y-T-P-R-E-F-V-T-V-V-L-K-A-V-F-R-M-S-E-D-T-G-R-R-V-M-M-T-A-H-R-F-G-S-A-V-V-V-V-C-E-R-D-I-A-E-T-K-A-K-E-A-T-D-L-G-K-E-A-G-F-P-L-M-F-T-T-E-P-E-E"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-V-E-K-V-P-M-T-Q-G-G-F-V-K-L-Q-E-E-L-R-F-R-Q-Q-E-E-R-P-R-I-I-E-A-I-A-E-A-R-A-H-G-D-L-S-E-N-A-E-Y-H-A-A-K-E-A-Q-S-H-N-E-G-R-I-T-E-L-E-D-L-T-A-R-A-E-V-I-D-L-S-K-M-S-G-S-K-I-K-F-G-A-T-V-K-L-I-D-E-D-S-D-E-E-K-T-Y-Q-I-V-G-D-Q-E-A-D-V-K-A-G-R-I-S-I-S-S-P-I-A-R-A-L-I-G-K-E-V-G-D-S-I-E-V-N-A-P-G-G-A-K-G-Y-E-I-L-A-V-Q-W-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-A-G-Q-L-K-L-Q-V-K-A-G-S-A-N-P-S-P-P-I-G-P-A-L-G-Q-R-G-I-N-I-M-E-F-C-K-A-F-N-A-A-T-Q-E-M-E-K-G-M-P-I-P-V-V-I-T-Y-Y-Q-D-K-S-F-T-F-A-M-K-Q-P-P-M-T-Y-W-L-K-K-E-A-K-I-T-S-G-S-K-T-P-G-K-G-A-K-V-G-S-I-T-K-A-Q-V-K-T-I-A-E-A-K-M-K-D-L-N-A-A-D-I-E-G-A-M-A-M-V-E-G-S-A-R-A-M-G-L-E-V-V-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-E-R-A-E-K-R-E-F-V-T-E-L-N-E-V-F-K-A-S-G-S-V-V-V-A-H-Y-A-G-V-T-V-A-Q-M-N-D-F-R-S-K-M-R-A-A-G-G-T-V-K-V-A-K-N-R-L-A-K-I-A-L-Q-G-T-E-S-E-G-M-T-N-L-F-K-G-Q-T-L-I-A-Y-S-V-D-P-M-I-A-P-K-V-V-M-D-F-A-K-T-N-D-K-V-V-V-L-G-G-S-M-G-A-T-T-L-N-A-E-A-V-K-S-L-A-T-L-P-S-L-D-E-L-R-A-K-L-L-G-L-L-N-A-P-A-T-R-V-A-T-V-V-A-A-P-A-S-Q-L-A-R-V-F-S-A-Y-A-K-K-D-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-D-L-A-K-I-V-E-D-L-S-T-L-T-V-L-E-A-A-E-L-S-K-L-L-E-E-K-W-G-V-S-A-A-A-P-V-A-V-A-A-A-G-G-A-G-A-A-A-A-V-E-E-E-K-T-E-F-D-V-V-L-V-D-A-G-A-N-K-I-N-V-I-K-E-V-R-A-I-T-G-L-G-L-K-E-A-K-D-L-V-E-G-A-P-K-A-V-K-E-A-V-S-K-A-E-A-A-D-L-K-K-K-L-E-D-A-G-A-K-V-D-V-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-V-N-Q-L-I-R-K-P-R-Q-A-Q-V-K-R-N-K-V-P-A-L-Q-E-N-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-I-R-L-T-N-G-F-E-V-I-G-Y-I-P-G-E-G-H-N-L-Q-E-H-S-V-V-M-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-I-R-G-V-L-D-T-Q-G-V-K-N-R-K-Q-R-R-S-K-Y-G-A-K-R-P-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-S-A-E-K-R-E-I-N-P-D-P-K-F-G-D-L-V-V-T-K-F-M-N-A-I-M-L-H-G-K-K-S-V-A-E-S-I-V-Y-G-A-F-D-V-V-Q-G-K-T-K-Q-E-P-L-G-V-F-H-S-A-L-D-N-V-A-P-H-V-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-D-V-R-P-E-R-R-Q-A-L-A-I-R-W-L-I-T-A-A-R-K-R-N-E-T-T-M-V-D-R-L-S-G-E-L-M-D-A-A-N-N-R-G-S-A-V-K-K-R-E-D-T-H-K-M-A-D-A-N-R-A-F-S-H-Y-R-W"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-T-G-Q-N-I-R-I-R-L-K-A-F-D-H-R-I-L-D-A-S-T-R-E-I-V-S-T-A-K-R-T-G-A-S-V-R-G-P-V-P-L-P-T-R-I-E-K-F-T-V-N-R-S-P-H-V-D-K-K-S-R-E-Q-F-E-M-R-T-H-K-R-L-L-D-I-V-D-P-T-P-Q-T-V-D-A-L-M-K-L-D-L-A-A-G-V-D-V-E-I-K-L"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-D-L-R-H-Y-D-V-I-V-S-P-S-I-T-E-K-S-T-L-V-S-E-Q-N-Q-V-V-F-N-V-A-K-T-A-S-K-P-E-I-K-A-A-V-E-A-L-F-G-V-K-V-T-A-V-N-T-L-I-R-K-G-K-T-R-R-F-R-G-F-A-G-K-L-K-D-V-K-K-A-V-V-T-L-A-E-G-Q-S-I-D-V-S-T-G-L"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-V-W-K-G-P-F-V-D-G-Y-L-L-T-K-A-E-K-V-R-E-S-G-R-N-E-V-I-K-I-W-S-R-R-S-T-I-L-P-Q-F-V-G-L-T-F-G-V-Y-N-G-S-K-H-V-P-V-S-V-N-E-D-M-V-G-H-K-F-G-E-F-S-P-T-R-T-Y-Y-G-H-G-A-D-K-K-A-K-R-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-K-A-K-T-E-R-R-L-K-D-N-E-A-Q-A-I-A-R-T-L-R-V-S-P-Q-K-L-N-L-V-A-A-L-I-R-G-K-K-V-D-R-A-L-A-E-L-E-F-S-R-K-R-I-A-G-T-V-K-K-T-L-E-S-A-I-A-N-A-E-N-N-H-D-L-D-V-D-A-L-V-V-A-E-A-Y-V-G-K-S-I-T-M-K-R-F-H-A-R-G-R-G-R-A-S-R-I-E-K-P-F-A-H-L-T-I-V-V-R-E-V-E-E-K-G-E-A-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-Y-R-K-Q-F-K-G-R-I-K-G-V-A-K-G-G-F-D-L-A-F-G-E-F-G-L-K-S-Q-E-P-N-R-V-N-A-R-E-I-E-A-A-R-R-A-I-T-R-Y-M-K-R-A-G-R-V-W-I-R-V-F-P-D-V-P-V-T-A-K-P-T-E-V-R-M-G-K-G-K-G-S-V-E-Y-W-A-C-K-V-K-P-G-R-M-M-F-E-I-D-G-V-T-E-E-I-A-R-E-A-L-R-L-G-A-A-K-L-S-V-K-T-R-F-V-Q-R-I-A-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-I-L-Q-G-V-V-V-S-D-K-N-E-K-T-V-V-V-R-V-E-R-R-F-A-H-P-L-M-Q-K-T-V-R-R-S-K-K-Y-K-A-H-D-E-N-N-Q-Y-K-V-G-D-V-V-S-I-E-E-C-A-P-I-S-K-D-K-R-W-T-V-V-A-A-Q-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-N-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-K-Y-A-S-V-G-D-I-I-V-V-S-I-K-E-A-I-P-R-G-R-V-K-K-G-D-V-M-K-A-V-V-V-R-T-A-K-D-I-R-R-A-D-G-S-V-I-R-F-D-N-N-A-A-V-L-I-D-N-K-K-E-P-I-G-T-R-I-F-G-P-V-P-R-E-L-R-A-K-N-H-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-K-I-R-K-G-D-N-V-V-V-L-T-G-K-D-K-G-R-T-G-E-V-I-Q-V-M-P-K-E-D-R-A-V-V-R-G-V-N-M-V-K-R-H-Q-R-Q-T-Q-A-Q-E-A-G-I-I-N-K-E-A-S-L-H-I-S-N-I-A-I-V-D-K-D-G-K-P-T-R-V-G-F-S-V-V-D-G-K-K-V-R-V-A-K-R-S-G-E-V-I-D-G"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-D-K-Y-E-P-R-L-K-T-E-Y-V-S-R-I-R-G-A-M-Q-E-K-F-S-Y-A-N-V-M-M-I-P-K-L-D-K-I-V-I-N-M-G-V-G-E-A-T-A-D-S-K-K-P-T-I-A-A-G-D-L-A-A-I-A-G-Q-K-P-V-I-T-K-A-R-N-S-I-A-G-F-K-V-R-E-H-M-P-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-R-L-I-N-I-A-L-P-R-V-R-D-F-R-G-L-N-P-K-S-F-D-G-R-G-N-F-A-M-G-I-K-E-H-I-V-F-P-E-I-N-Y-D-K-V-D-Q-M-W-G-M-D-I-I-V-C-T-T-A-T-S-D-D-E-A-R-A-L-L-T-E-F-N-F-P-F-R-H"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-L-G-D-M-L-T-R-I-R-N-G-A-A-R-R-K-S-S-V-S-T-P-A-S-S-L-R-A-R-V-L-D-V-L-Q-S-E-G-Y-I-R-G-Y-S-K-V-D-F-E-N-G-K-A-E-F-T-I-E-L-K-Y-Y-E-G-A-S-V-I-R-E-I-G-R-V-S-K-P-G-R-R-V-Y-V-S-V-K-S-I-P-Q-V-A-N-G-L-G-I-T-I-L-S-T-P-K-G-V-M-A-D-H-Q-A-R-E-Q-N-V-G-G-E-V-L-C-S-V-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-P-V-P-V-P-A-G-V-T-A-N-V-D-G-Q-K-V-T-A-K-G-P-K-G-E-L-F-F-V-A-N-D-D-I-Q-L-K-L-E-D-N-G-V-S-V-T-P-A-N-G-T-K-E-A-R-S-K-W-G-M-S-R-T-M-I-E-N-I-F-K-G-V-K-D-G-Y-E-R-K-L-E-I-N-G-V-G-Y-R-A-A-L-Q-G-K-N-L-Q-L-A-L-G-F-S-H-D-V-V-Y-E-P-P-V-G-I-T-I-A-V-P-K-P-T-E-I-I-V-S-G-I-N-K-Q-Q-V-G-Q-V-A-A-E-I-R-E-Y-R-G-P-E-P-Y-K-G-K-G-V-K-Y-A-E-E-R-I-V-R-K-E-G-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-S-R-K-E-A-L-A-R-R-A-S-R-V-R-R-Q-I-K-A-V-A-N-G-R-P-R-L-S-V-H-R-S-S-K-N-I-Y-A-Q-I-I-D-D-V-A-G-K-T-L-A-S-A-S-T-L-E-A-D-L-R-S-S-L-K-T-G-A-D-V-A-A-A-A-V-V-G-K-L-V-A-E-R-G-V-K-A-G-V-K-D-V-V-F-D-R-G-A-F-I-Y-H-G-R-I-K-A-V-A-E-A-A-R-E-G-G-L-N-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-Q-E-K-R-G-S-R-D-D-R-Q-N-R-E-E-R-D-S-E-F-V-D-K-L-V-A-I-N-R-V-A-K-V-V-K-G-G-R-R-F-G-F-A-A-L-V-V-V-G-D-Q-K-G-R-V-G-F-G-H-G-K-A-R-E-V-P-E-A-I-R-K-A-T-E-S-A-K-R-D-L-I-F-V-P-L-R-D-G-R-T-L-H-H-D-V-N-G-R-H-G-A-G-K-V-L-L-R-S-A-K-A-G-T-G-I-I-A-G-G-P-M-R-A-V-F-E-T-L-G-V-H-D-V-V-A-K-S-T-G-S-S-N-P-Y-N-M-V-R-A-T-F-D-A-L-K-H-Q-V-H-P-K-D-I-A-A-Q-R-G-L-K-Y-A-T-L-Q-A-R-R-A-A-S-G-N-A-S-E-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-E-I-R-D-N-E-G-S-S-K-D-R-I-R-V-G-R-G-I-G-S-G-K-G-K-T-G-G-R-G-V-K-G-Q-K-A-R-S-G-V-A-I-N-G-F-E-G-G-Q-M-P-I-Y-R-R-L-P-K-R-G-F-N-N-I-F-G-S-E-F-A-V-V-S-L-G-R-I-Q-T-A-I-D-A-K-K-L-D-A-S-A-T-I-D-A-A-A-L-K-A-A-G-V-I-R-R-V-K-D-G-V-R-I-L-A-D-G-E-L-T-S-K-V-A-F-E-V-A-G-A-S-K-P-A-L-E-K-I-E-K-A-G-S-S-I-K-L-L-A-V-A-V-E-A-S-E"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-T-A-K-R-V-V-I-A-L-T-Y-I-H-G-I-G-P-K-F-A-Q-E-I-M-D-K-V-G-I-P-A-E-K-R-V-H-Q-L-T-D-A-E-V-L-Q-I-R-E-A-I-D-R-D-Y-Q-V-E-G-D-L-R-R-E-T-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-H-T-N-A-R-T-R-K-G-P-A-K-A-I-A-G-K-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-E-A-A-R-V-R-R-R-E-R-K-N-I-T-S-G-V-A-H-V-N-S-T-F-N-N-T-M-I-T-I-T-D-A-Q-G-N-A-I-A-W-S-S-A-G-A-K-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-I-A-A-E-D-C-A-K-K-A-Q-E-H-G-M-K-S-L-E-V-E-V-C-G-P-G-S-G-R-E-S-A-L-R-A-L-Q-A-A-G-F-M-I-T-S-I-R-D-V-T-P-I-P-H-N-G-C-R-P-R-K-K-R-R-V"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-V-W-H-W-L-I-V-L-V-I-V-L-V-L-F-G-R-G-K-I-P-E-L-M-G-D-V-A-K-G-I-K-S-F-K-K-G-M-A-D-E-D-Q-T-P-P-P-A-D-A-N-A-N-A-K-T-V-D-H-K-A-D-E-I-K"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis Is involved in the transfer of long hydroxylated fatty acids to lipid A ### SEQUENCE -M-G-V-T-A-T-F-D-K-V-A-D-I-I-A-E-T-S-E-I-D-R-E-T-I-T-P-E-S-H-T-I-D-D-L-G-I-D-S-L-D-F-L-D-I-V-F-A-I-D-K-E-F-G-I-K-I-P-L-E-Q-W-T-Q-E-V-N-E-G-K-V-S-T-E-E-Y-F-V-L-K-N-L-C-A-K-I-D-E-L-R-A-A-K-G"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-V-N-K-V-I-L-I-G-N-V-G-A-D-P-E-I-R-R-T-Q-D-G-R-P-I-A-N-L-R-I-A-T-S-E-T-W-R-D-R-N-S-G-E-R-K-E-K-T-E-W-H-T-V-V-V-F-N-E-G-L-C-K-V-V-E-Q-Y-V-K-K-G-A-K-L-Y-I-E-G-Q-L-Q-T-R-K-W-Q-D-Q-T-G-N-D-R-Y-S-T-E-I-V-L-Q-G-F-N-S-T-L-T-M-L-D-G-R-G-E-G-G-G-G-R-S-G-G-G-D-F-G-G-G-N-D-Y-G-S-G-G-G-Y-D-Q-Q-S-S-P-R-G-G-S-S-R-G-G-G-Q-P-S-G-G-F-S-N-D-M-D-D-D-I-P-F"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-N-I-A-L-V-A-T-G-G-A-I-G-S-V-F-R-Y-L-V-G-V-W-S-M-R-L-A-G-P-N-F-P-W-G-T-L-A-V-N-I-V-G-S-F-L-I-G-L-L-V-E-L-V-A-R-R-L-N-A-S-I-E-M-R-L-F-L-V-T-G-V-L-G-G-F-T-T-F-S-S-F-S-L-D-A-V-S-L-F-E-R-G-A-L-G-L-S-A-F-Y-I-L-A-S-L-V-V-S-I-A-A-V-F-A-G-L-A-L-G-R-N-L-F"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-L-K-F-T-A-E-H-E-W-L-K-F-E-G-D-I-A-T-V-G-I-T-S-H-A-A-E-Q-L-G-D-L-V-F-V-E-L-P-E-V-G-A-T-F-A-K-D-G-D-A-A-T-V-E-S-V-K-A-A-S-D-V-Y-C-P-L-D-G-E-V-V-E-I-N-Q-A-I-V-D-D-P-S-L-V-N-S-D-P-Q-G-A-G-W-F-F-K-L-K-L-S-N-A-A-D-A-E-T-L-L-D-E-A-A-Y-K-E-L-I-A"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-E-R-S-Q-N-L-Q-D-L-F-L-N-T-V-R-K-Q-K-I-S-L-T-I-F-L-I-N-G-V-K-L-T-G-V-V-T-S-F-D-N-F-C-V-L-L-R-R-D-G-H-S-Q-L-V-Y-K-H-A-I-S-T-I-M-P-G-Q-P-M-Q-M-F-E-S-E-E-G-A-A"} +{"text": "### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate ### SEQUENCE -M-K-T-V-T-A-R-P-L-T-A-E-A-F-A-P-Y-G-S-V-A-D-I-S-E-L-E-N-L-V-S-L-A-D-A-Y-E-G-T-G-E-A-K-T-P-V-L-Q-L-V-Q-A-K-A-M-S-G-S-P-V-I-S-Q-M-E-I-H-P-F-S-S-Q-T-F-L-P-L-D-Q-S-S-S-L-I-V-V-C-E-A-G-E-D-G-M-P-D-E-S-T-I-K-A-F-L-A-S-P-S-Q-I-V-T-Y-R-H-G-V-M-H-H-R-L-T-P-L-A-P-S-G-R-F-A-M-T-M-W-Q-T-G-R-G-G-D-T-V-L-Y-P-L-H-T-P-V-S-V-D-I-S-D-I-T-P"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-G-I-D-L-N-D-I-K-R-R-M-D-G-A-I-N-A-F-K-S-D-I-A-S-L-R-T-G-R-A-S-A-N-I-L-D-P-V-T-I-D-A-Y-G-S-R-V-P-L-N-Q-V-A-N-I-T-V-P-E-P-R-M-L-G-V-N-I-W-D-K-S-M-V-N-A-V-D-R-A-I-R-E-S-N-L-G-L-N-P-I-V-D-G-Q-N-L-R-I-P-L-P-E-L-N-E-E-R-R-K-S-L-V-K-V-A-H-E-Y-S-E-K-A-K-V-A-I-R-H-V-R-R-D-G-M-D-G-L-K-K-A-E-K-D-G-D-I-G-Q-D-E-S-R-G-Q-S-E-K-V-Q-K-M-T-D-D-T-I-S-E-I-D-R-L-L-A-E-K-E-K-E-I-M-Q-V"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-I-A-K-P-I-Y-M-Q-G-E-G-D-G-E-D-G-G-T-N-R-G-T-S-V-I-T-R-V-K-P-K-T-K-R-P-N-L-Y-R-V-L-L-L-N-D-D-Y-T-P-M-E-F-V-I-H-I-L-E-R-F-F-Q-K-D-R-E-A-A-T-R-I-M-L-H-V-H-Q-H-G-V-G-E-C-G-V-F-T-Y-E-V-A-E-T-K-V-S-Q-V-M-D-F-A-R-Q-H-Q-H-P-L-Q-C-V-M-E-K-K"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-V-D-L-A-T-V-K-R-V-A-R-L-A-R-I-A-V-S-E-E-E-A-Q-N-M-L-G-Q-L-N-G-I-L-G-F-V-E-Q-L-S-E-V-N-V-D-G-V-E-P-M-T-S-V-T-P-V-E-M-K-K-R-A-D-V-V-T-D-G-N-K-A-D-D-I-V-A-N-A-P-A-T-D-R-D-F-F-M-V-P-K-V-V-E"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-T-L-T-I-E-E-L-A-Q-T-L-Q-P-A-Q-A-I-A-G-L-D-L-G-T-K-T-I-G-L-A-M-S-D-L-S-R-R-F-A-T-P-R-P-V-I-K-R-V-K-F-T-Q-D-A-Q-V-L-L-A-F-A-E-K-E-K-V-A-A-F-V-I-G-L-P-I-N-M-D-G-S-A-G-P-R-A-Q-A-T-R-A-F-V-R-T-M-G-E-K-T-A-L-P-F-I-Y-W-D-E-R-L-S-T-V-A-A-E-R-A-L-L-E-M-D-V-S-R-A-K-R-A-E-R-I-D-S-A-A-A-S-F-I-L-Q-G-A-L-D-R-L-S-A-L-T-R-A-A-D"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-S-T-F-V-Q-K-P-A-E-V-E-K-K-W-I-I-I-D-A-E-G-L-V-V-G-R-L-A-T-I-V-A-T-R-L-R-G-K-H-K-A-T-F-T-P-H-V-D-D-G-D-N-V-I-V-I-N-A-E-K-V-A-F-T-G-K-K-Y-S-D-K-K-Y-Y-W-H-T-G-H-P-G-G-I-K-E-R-T-A-R-Q-I-I-E-G-R-F-P-E-R-V-V-E-K-A-I-E-R-M-I-P-R-G-P-L-G-R-R-Q-M-K-N-L-R-V-Y-A-G-S-N-H-P-H-E-A-Q-Q-P-T-V-L-D-V-A-A-L-N-K-K-N-V-R-S-A"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-G-K-T-V-T-R-A-D-L-A-E-S-V-F-R-K-V-G-L-S-R-T-E-S-A-E-L-V-E-T-I-I-D-E-I-C-N-A-I-T-R-G-E-V-V-K-L-S-S-F-A-T-F-Q-I-R-E-K-N-E-R-I-G-R-N-P-K-T-G-E-E-V-P-I-S-P-R-R-V-M-T-F-K-A-S-N-V-L-K-Q-R-I-L-K-A-H-T-A-R-K-A-K-Q-K-G-Q-K-A-G-V"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-D-V-E-N-G-G-E-P-R-Q-P-S-V-K-P-A-N-Q-R-G-A-A-R-L-A-A-V-Q-A-L-Y-Q-M-D-V-G-G-T-G-V-M-E-V-V-A-E-Y-E-A-H-R-L-G-Q-E-V-D-G-D-T-Y-L-K-A-D-P-S-W-F-R-S-I-V-S-G-V-V-R-D-Q-T-K-I-D-P-L-V-R-S-A-L-L-E-D-W-P-L-S-R-L-D-A-T-V-R-A-I-L-R-A-G-T-F-E-I-L-E-R-K-D-V-P-V-A-V-I-V-T-E-Y-V-E-I-A-R-A-F-F-E-H-D-E-P-K-L-V-N-A-V-L-D-R-I-A-K-Q-V-R-G-E-A-K-R"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-S-K-P-H-L-L-I-V-E-A-R-F-Y-D-D-M-A-D-A-L-L-E-G-A-K-F-A-L-E-E-A-G-A-T-Y-D-V-I-T-V-P-G-A-L-E-I-P-A-A-I-A-M-A-L-D-G-A-D-N-D-G-T-E-Y-D-G-F-V-A-L-G-M-V-I-R-G-E-T-Y-H-F-D-I-V-S-N-E-S-S-R-A-L-M-D-L-A-V-S-E-S-L-P-I-G-N-G-I-L-T-V-E-N-D-E-Q-A-W-A-R-V-R-R-S-D-K-D-K-G-G-F-A-A-R-A-A-L-T-M-I-E-L-K-K-K-L-G-G"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-F-C-G-S-E-D-T-Q-V-K-D-S-R-P-A-E-D-N-T-S-I-R-R-R-R-I-C-P-D-C-G-G-R-F-T-T-Y-E-R-V-Q-L-R-E-L-M-V-I-K-K-S-G-R-K-L-P-F-D-R-E-K-L-V-R-S-F-E-I-A-L-R-K-R-P-V-D-R-D-R-I-E-R-A-V-S-G-I-A-R-R-L-E-S-S-G-E-T-E-I-P-S-E-E-I-G-L-Q-V-L-E-A-L-K-S-L-D-D-V-A-F-V-R-Y-A-S-V-Y-R-D-F-S-H-A-E-D-F-E-N-V-I-A-E-I-N-A-K-I-A-R-D-T-D-A-G-A"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-D-I-A-E-R-V-K-K-I-V-I-D-H-L-G-V-D-A-D-K-V-V-E-G-A-S-F-I-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-F-E-E-E-F-G-V-E-I-P-D-D-A-A-D-S-I-L-T-V-G-D-A-V-K-F-I-E-K-A-Q-A"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-L-Y-E-H-I-F-L-A-R-Q-D-I-S-A-Q-Q-V-D-A-L-V-E-Q-Y-K-G-V-I-E-S-F-G-G-K-V-G-R-V-E-N-W-G-L-K-S-L-T-Y-R-I-K-K-N-R-K-A-H-Y-A-L-M-D-I-D-A-P-A-A-A-V-H-E-V-E-R-Q-M-R-I-N-E-D-V-L-R-Y-M-T-I-A-V-E-A-H-E-E-G-P-S-A-M-M-Q-K-R-D-R-D-D-R-P-R-R-D-G-D-R-P-D-R-G-P-R-E-D-R-G-P-R-P-P-R-E-G-G-F-G-D-R-E-D-R-P-R-R-P-R-E-D-R-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-D-T-S-S-S-Q-A-R-R-P-F-H-R-R-R-K-T-C-P-F-S-G-A-N-A-P-K-I-D-Y-K-D-V-R-L-L-Q-R-Y-I-S-E-R-G-K-I-V-P-S-R-I-T-A-V-S-Q-K-K-Q-R-E-L-A-Q-A-I-K-R-A-R-F-L-G-L-L-P-Y-V-V-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-D-V-I-L-L-E-R-I-N-K-L-G-Q-M-G-E-T-V-K-V-R-D-G-Y-A-R-N-F-L-L-P-Q-G-K-A-L-R-A-N-A-A-N-K-T-R-F-E-T-E-R-A-T-L-E-A-R-N-L-E-R-K-S-E-A-Q-T-V-A-E-A-L-A-G-K-S-F-I-V-V-R-S-A-G-E-T-G-Q-L-Y-G-S-V-A-A-R-D-V-V-E-I-L-G-A-E-G-F-N-I-G-R-N-Q-V-E-L-N-T-P-I-K-T-I-G-L-H-N-V-T-L-H-L-H-A-E-V-E-L-Q-V-E-L-N-V-A-R-S-A-E-E-A-E-R-Q-S-K-G-E-S-L-T-S-A-D-A-I-Y-G-V-D-E-D-A-L-R-P-E-D-F-F-D-P-E-A-D-G-N-E-D-D-E"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-I-G-L-G-S-D-L-I-D-I-R-R-V-E-K-S-I-E-R-F-G-E-R-F-T-H-R-C-F-T-D-I-E-R-A-K-S-D-G-R-K-N-R-A-A-S-Y-A-K-R-F-A-A-K-E-A-C-S-K-A-L-G-T-G-L-A-N-G-V-F-W-K-D-M-G-V-V-N-L-P-G-G-K-P-T-M-I-L-T-N-G-A-G-A-R-L-A-A-M-L-P-A-G-H-R-A-N-I-H-L-T-I-T-D-D-F-P-Y-A-Q-A-F-V-I-I-E-A-L-P-V-N-G"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-P-K-G-S-Q-R-V-V-N-K-I-V-A-E-N-R-K-A-R-F-N-Y-E-I-I-D-T-Y-E-A-G-L-V-L-T-G-T-E-V-K-S-L-R-E-G-K-A-N-I-A-E-S-Y-A-S-D-E-G-D-E-I-W-L-I-N-S-H-L-P-E-Y-L-Q-A-N-R-F-N-H-E-P-R-R-R-R-K-L-L-L-N-K-R-E-I-N-R-L-R-A-G-I-N-R-D-G-M-T-L-V-P-L-K-V-Y-F-N-E-K-G-R-A-K-L-E-L-A-L-A-K-G-K-K-L-H-D-K-R-E-T-E-K-E-R-D-W-N-R-Q-K-S-R-L-L-K-G-N-S-Q"} +{"text": "### FUNCTION Low-spin monoheme cytochrome c ### SEQUENCE -M-C-M-K-L-K-T-I-T-A-A-M-L-F-G-C-L-C-A-G-A-V-Y-A-A-G-E-V-E-K-R-E-G-M-M-K-Q-I-G-G-S-M-G-A-L-A-A-I-S-K-G-E-K-P-F-D-A-A-A-V-K-A-A-V-T-T-I-S-T-N-A-K-A-F-P-D-Q-F-P-V-G-S-E-T-G-S-A-A-A-P-A-I-W-E-N-F-D-D-F-K-A-K-A-A-K-L-G-T-D-A-D-A-V-L-A-N-L-P-T-D-Q-A-G-V-A-T-A-M-K-T-L-G-A-D-C-G-T-C-H-Q-T-Y-R-L-K-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-N-M-T-E-N-A-N-T-A-D-V-S-G-Y-S-F-E-K-A-V-A-E-L-E-S-I-V-A-R-L-E-R-G-D-V-A-L-D-E-S-I-A-I-Y-E-R-G-E-A-L-K-K-H-C-E-T-L-L-N-A-A-E-K-R-I-E-K-I-R-L-D-R-A-G-K-P-Q-G-V-E-P-L-D-G-E"} +{"text": "### FUNCTION Has a post-transcriptional repressor function in flagellum biogenesis Associates with the 5'-UTR of fljK mRNA and promotes its degradation ### SEQUENCE -M-K-S-T-L-R-I-S-L-K-S-G-E-K-I-F-I-N-G-A-V-L-R-V-D-R-K-V-A-L-E-F-L-N-D-V-T-F-L-L-E-N-H-V-L-Q-P-D-Q-A-T-T-P-L-R-Q-L-Y-F-I-A-Q-M-I-L-I-N-P-E-G-R-E-Q-S-T-N-M-F-R-K-S-V-S-M-L-L-N-C-F-Q-H-D-E-I-L-A-E-L-K-R-I-D-G-L-V-A-S-G-K-A-F-E-A-L-K-A-I-R-G-L-Y-T-I-E-E-K-I-L-S-N-Q-E-M-T-P-A-T-I-E-Q-I-R-K-E-I-A-P-W-R"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-T-K-E-E-V-L-E-F-P-G-I-V-T-E-L-L-P-N-A-T-F-R-V-K-L-E-N-E-H-E-I-I-A-H-T-A-G-R-M-R-K-N-R-I-R-V-L-A-G-D-K-V-L-V-E-M-T-P-Y-D-L-T-K-G-R-I-T-Y-R-F-K"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-N-E-F-K-T-F-I-A-R-G-N-V-M-D-L-A-V-G-V-I-I-G-A-A-F-S-K-I-V-D-S-V-V-N-D-L-I-M-P-I-V-G-A-I-F-G-G-F-D-F-S-N-Y-F-L-P-L-S-S-N-V-N-A-T-S-L-A-A-A-R-E-Q-G-A-V-F-A-Y-G-N-F-L-T-V-L-I-N-F-L-I-L-A-W-I-I-F-L-M-V-K-G-V-N-K-L-R-D-S-V-D-R-K-K-I-E-E-K-P-D-A-A-P-P-P-E-D-V-K-L-L-T-E-I-R-D-L-L-K-T-R"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-S-E-T-K-K-Q-P-G-R-L-K-N-R-S-E-F-L-A-V-Q-A-G-E-K-R-R-G-S-T-F-L-V-E-V-L-D-R-R-A-P-E-T-E-P-R-V-G-F-T-V-T-K-R-Q-G-N-A-V-E-R-N-R-M-R-R-R-L-K-E-A-V-R-L-S-A-G-V-A-M-K-P-G-H-D-Y-V-I-V-A-R-R-D-V-L-D-T-A-F-P-K-L-Q-S-L-L-I-E-R-I-E-G-T-A-K-P-K-R-S-Q-E-T-R-S-R-K-E"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-T-I-K-P-L-I-I-L-P-D-P-V-L-R-Q-Q-S-K-L-I-E-Q-V-D-A-E-V-L-R-L-A-D-D-M-L-E-T-M-Y-D-A-P-G-I-G-L-A-A-I-Q-I-G-V-P-R-R-M-L-V-I-D-V-A-R-E-G-E-E-K-T-P-V-V-F-I-N-P-E-I-L-K-V-S-D-D-I-S-T-Y-E-E-G-C-L-S-I-P-D-Y-Y-A-E-V-E-R-P-A-S-L-T-V-Q-Y-V-G-R-D-G-K-Q-Q-T-V-E-A-D-G-L-L-A-T-C-L-Q-H-E-I-D-H-L-N-G-V-L-F-I-D-H-I-S-R-L-K-R-D-M-V-I-K-K-F-T-K-A-A-R-A-K-I"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-A-L-D-I-Q-I-S-V-E-A-E-G-W-S-S-E-E-N-L-A-A-F-A-T-K-V-L-N-A-A-V-D-F-L-K-R-E-E-E-Q-P-F-P-K-M-P-V-E-L-S-L-V-F-T-D-D-E-N-I-R-E-I-N-A-E-W-R-D-K-D-K-A-T-N-V-L-S-F-P-A-F-P-L-E-P-G-G-M-P-G-P-M-L-G-D-I-V-I-A-R-E-T-V-E-R-E-A-L-E-L-D-K-S-F-E-D-H-L-T-H-L-L-V-H-G-F-L-H-L-F-G-Y-D-H-M-D-E-E-E-A-E-E-M-E-S-L-E-T-R-I-L-A-V-L-G-L-S-D-P-Y-A-G-Q-E-P-L"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-I-K-S-E-L-V-Q-I-V-A-A-R-N-P-H-L-Y-H-R-D-V-E-N-I-V-N-A-V-L-D-E-I-T-D-A-L-A-A-G-N-R-V-E-L-R-G-F-G-A-F-S-V-K-N-R-P-S-R-S-G-R-N-P-R-T-G-E-S-V-F-V-E-E-K-W-V-P-F-F-K-T-G-K-E-L-R-E-R-L-N-P-G-M-G-D-E-E-D-D"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-T-S-A-K-K-A-T-R-K-I-A-R-R-T-A-V-N-K-A-R-R-S-R-V-R-G-F-I-R-K-V-E-E-A-I-A-T-G-D-L-A-V-A-T-E-A-L-K-A-A-Q-P-E-I-Q-R-A-A-T-R-G-V-L-H-G-N-T-A-S-R-K-V-S-R-L-A-Q-R-V-K-A-L-S-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-V-Q-N-D-N-R-P-L-L-R-L-V-R-L-A-N-G-A-D-L-E-L-P-S-Y-E-T-R-G-A-A-G-M-D-L-R-A-A-V-P-A-D-E-P-L-N-L-Q-P-G-E-R-A-L-V-P-T-G-F-I-F-E-V-P-Q-G-Y-E-A-Q-I-R-P-R-S-G-L-A-I-K-N-G-I-T-C-L-N-S-P-G-T-V-D-S-D-Y-R-G-E-V-K-V-I-L-A-N-L-G-Q-D-D-F-T-I-E-R-G-M-R-I-A-Q-M-V-I-A-P-V-T-Q-V-T-V-S-E-V-T-E-T-S-E-T-A-R-G-A-G-G-F-G-S-T-G-V"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-T-S-R-A-K-H-T-K-T-L-K-A-A-K-G-F-Y-G-R-R-K-N-T-I-R-A-A-K-A-A-V-D-R-S-K-Q-Y-A-Y-R-D-R-K-V-N-K-R-N-F-R-A-L-W-I-Q-R-I-N-A-A-V-R-E-S-G-L-T-Y-G-R-F-I-D-G-L-N-K-A-G-I-E-V-D-R-K-V-L-S-D-M-A-I-H-E-P-A-A-F-G-A-L-V-E-A-A-K-K-A-L-E-Y-L-K-D-A-G-T-T-N-E-F-E-T-A-V-K"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-E-G-Q-R-C-I-A-L-I-A-H-D-E-K-K-D-D-M-A-D-F-A-R-H-H-Q-K-V-L-A-S-F-R-I-V-A-T-G-T-T-G-G-R-V-Q-E-A-C-P-G-L-E-V-I-R-L-K-S-G-P-L-G-G-D-Q-Q-I-G-A-M-I-A-T-G-E-V-D-M-L-I-F-F-T-D-P-L-T-A-M-P-H-D-V-D-V-K-A-L-T-R-L-A-T-V-Y-D-I-P-M-A-L-N-R-A-T-A-E-N-L-I-D-F-N-S-A-D"} +{"text": "### FUNCTION May be involved in electron transfer from bc1 complex to aa3 ### SEQUENCE -M-N-S-Y-V-N-M-G-V-G-A-L-L-G-T-V-F-V-L-M-S-V-S-I-A-S-E-G-I-F-H-A-P-A-P-E-K-E-G-Y-T-I-V-A-A-E-S-G-G-G-E-A-G-G-G-E-A-A-A-A-A-T-P-I-A-K-L-L-A-S-A-D-A-A-K-G-E-A-V-F-K-K-C-T-S-C-H-T-G-E-S-G-G-A-N-K-V-G-P-N-L-F-D-V-V-N-R-P-I-A-S-H-E-G-F-S-Y-S-A-G-M-K-D-F-S-K-G-A-S-V-H-W-D-Y-D-H-L-N-Y-F-L-E-A-P-K-K-H-V-P-G-T-A-M-G-F-A-G-V-K-K-E-T-E-R-A-D-L-I-A-Y-L-R-S-L-S-A-N-P-A-P-L-P-D-P-N-A-A-P-A-P-M-N"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-R-D-I-M-G-M-M-G-K-V-K-E-M-Q-S-K-M-E-K-V-Q-Q-E-I-A-A-L-E-I-E-G-R-A-G-G-G-L-V-T-V-I-L-N-G-K-G-E-M-R-G-L-K-I-D-P-S-L-F-K-E-D-E-V-E-I-L-E-D-L-I-V-A-A-H-K-D-A-K-E-K-G-E-A-Q-A-Q-E-K-M-A-D-L-T-A-G-L-P-L-P-P-G-M-K-L-P-F"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-D-T-A-Q-E-P-R-L-I-T-E-T-G-I-D-Q-R-I-A-E-I-I-E-P-V-L-T-G-M-G-Y-L-L-V-R-V-R-L-S-N-Q-N-G-M-T-L-Q-V-M-A-E-R-E-D-G-T-M-N-V-Q-D-C-E-A-I-S-M-A-I-S-P-V-L-D-V-E-D-P-V-E-K-A-Y-H-L-E-V-S-S-P-G-I-D-R-P-M-V-R-K-T-D-F-T-R-W-Q-G-H-L-V-K-V-E-T-S-I-L-V-E-N-R-K-R-F-R-G-K-I-V-E-V-D-A-D-S-F-K-L-E-R-D-Q-I-A-Y-G-E-E-P-T-V-V-V-P-F-N-A-L-S-D-A-K-L-I-L-T-D-D-L-I-R-D-A-L-R-A-D-K-A-A-K-A-A-A-A-N-Q-N-D-E-N-E-A-D-E-D"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-A-T-S-S-A-P-S-Q-R-M-L-R-V-G-E-Q-V-R-A-A-L-T-Q-I-L-Q-R-G-E-V-R-D-D-L-I-E-G-T-V-I-S-I-S-E-V-R-M-S-P-D-L-K-I-A-T-A-Y-V-T-P-L-G-V-A-D-H-T-D-I-I-S-A-L-N-R-H-A-K-F-M-R-G-R-L-G-P-Q-L-R-Q-M-K-Y-M-P-E-L-R-F-R-D-D-T-S-F-D-N-Y-Q-K-I-D-A-L-L-R-S-P-E-V-Q-R-D-L-G-P-S-N-E-K-D-D-E-Q-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-I-T-A-E-R-K-A-A-L-I-T-E-Y-A-T-K-A-G-D-T-G-S-P-E-V-Q-V-A-I-L-T-E-R-I-N-N-L-T-G-H-F-K-D-H-K-K-D-N-H-S-R-R-G-L-L-T-L-V-S-S-R-R-S-L-L-D-Y-L-K-K-K-D-E-A-R-Y-T-K-L-I-G-A-L-G-I-R-R"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-G-L-I-V-Y-Y-S-S-R-S-E-N-T-H-R-F-L-L-K-L-E-R-R-L-F-R-L-P-L-G-A-E-E-D-V-P-Q-V-S-E-P-Y-V-L-V-T-P-T-Y-G-G-G-G-T-K-G-A-V-P-K-P-V-I-R-F-L-N-E-P-S-N-R-N-L-I-R-G-V-I-A-A-G-N-T-N-F-G-A-A-F-A-S-A-G-D-I-V-S-R-K-C-A-V-P-F-L-Y-R-F-E-L-L-G-T-E-E-D-V-A-N-V-K-H-G-L-E-R-F-W-T-R"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-T-A-E-N-G-A-Q-G-A-V-S-P-S-L-N-I-L-A-Q-Y-I-K-D-L-S-F-E-N-P-G-A-P-R-S-L-Q-G-R-E-N-A-P-A-I-N-I-N-V-N-V-N-A-N-P-I-S-G-S-D-F-D-V-V-L-T-L-N-A-E-A-K-D-G-D-K-I-L-F-A-A-E-L-V-Y-G-G-V-F-R-I-A-G-F-P-Q-E-H-M-L-P-V-L-F-I-E-C-P-R-L-L-F-P-F-A-R-Q-I-I-A-D-V-T-R-N-G-G-F-P-P-L-M-I-D-P-I-D-F-S-Q-M-F-A-Q-R-V-A-E-E-Q-A-K-A-Q-V-Q-A-V-P-N"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-K-Q-E-L-I-L-A-S-S-S-A-S-R-Q-M-L-M-R-N-A-G-L-T-F-S-A-I-P-A-D-I-D-E-R-A-L-D-E-Q-L-E-R-D-G-A-S-P-E-E-V-A-L-E-L-A-R-A-K-A-L-A-V-S-A-L-H-P-E-A-L-V-L-G-C-D-Q-T-M-A-L-G-T-R-V-Y-H-K-P-K-N-M-A-E-A-A-T-H-L-L-S-L-S-G-K-V-H-R-L-N-S-A-A-V-L-V-H-N-G-K-V-V-W-Q-T-V-S-S-A-E-L-A-V-R-T-L-S-A-E-F-V-S-R-H-L-Q-R-V-G-E-K-A-L-S-S-V-G-A-Y-Q-L-E-R-E-G-I-Q-L-F-T-S-I-E-G-D-Y-F-T-I-L-G-L-P-L-L-P-L-L-S-K-L-R-D-M-D-V-I-D-G"} +{"text": "### FUNCTION Has low cytotoxic activity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-K-C-H-N-S-P-L-S-L-V-Y-Q-T-C-P-I-G-Q-N-I-C-F-K-I-N-V-K-E-A-P-S-I-P-V-K-R-A-C-A-A-T-C-P-K-S-S-A-L-V-K-V-V-C-C-K-T-D-K-C-N"} +{"text": "### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-E-C-A-K-T-G-T-C-N-C-G-G-S-C-S-C-T-N-C-S-C-T-S-C-K-K-S-C-C-S-C-C-P-A-G-C-S-K-C-A-S-G-C-V-C-K-G-K-T-C-D-T-S-C-C-Q"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-I-R-Y-P-M-A-V-G-L-N-K-G-H-K-V-T-K-N-V-S-K-P-R-H-C-R-R-R-G-R-L-T-K-H-T-K-F-V-R-D-M-I-R-E-V-C-G-F-A-P-Y-E-R-R-A-M-E-L-L-K-V-S-K-D-K-R-A-L-K-F-I-K-K-R-V-G-T-H-I-R-A-K-R-K-R-E-E-L-S-N-V-L-A-A-M-R-K-A-A-A-K-K-D"} +{"text": "### FUNCTION Binds to muscle nicotinic acetylcholine receptor and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-M-T-C-C-N-Q-Q-S-S-Q-P-K-T-T-T-N-C-A-E-S-S-C-Y-K-K-T-W-S-D-H-R-G-T-R-I-E-R-G-C-G-C-P-Q-V-K-R-G-I-K-L-E-C-C-H-T-N-E-C-N-N"} +{"text": "### FUNCTION Binds with high affinity to muscular and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-D-S-L-S-C-Y-L-G-Y-K-R-S-Q-T-C-P-P-G-E-K-V-C-F-V-K-S-W-C-D-A-F-C-G-S-R-G-K-R-I-E-M-G-C-A-A-T-C-P-T-V-K-D-G-I-D-I-T-C-C-A-T-D-N-C-N-T-Y-A-N-W-G-S-G"} +{"text": "### FUNCTION Binds with high affinity to muscular and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission ### SEQUENCE -M-K-I-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-A-Y-T-R-T-C-F-R-T-P-Y-K-P-E-T-C-P-P-G-Q-N-L-C-Y-K-K-S-W-C-D-A-F-C-S-S-R-G-K-V-I-E-L-G-C-T-A-K-C-P-T-V-K-D-G-K-D-I-T-C-C-A-T-D-N-C-N-T-V-A-N-W-K-S-R"} +{"text": "### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-H-R-K-M-A-V-K-T-L-S-V-W-L-L-L-V-G-T-L-V-P-Q-H-C-C-Q-H-W-S-Y-G-L-S-P-G-G-K-R-Q-L-D-S-L-S-Q-T-L-G-N-V-V-E-E-F-P-R-V-D-S-P-C-S-V-L-G-G-A-E-E-S-P-F-A-G-I-Y-R-M-K-G-F-L-G-S-I-T-D-R-G-N-R-T-Q-N-I"} +{"text": "### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-C-A-S-R-L-V-L-L-L-G-L-L-L-C-V-G-A-H-L-S-S-G-Q-H-W-S-H-G-W-Y-P-G-G-K-R-E-L-D-S-F-G-T-S-E-I-S-E-E-I-K-L-C-E-A-G-E-C-S-Y-L-R-P-Q-R-R-N-I-L-R-N-I-L-L-D-A-L-A-R-E-L-Q-K-R-K"} +{"text": "### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-E-A-S-S-R-L-V-V-Q-V-L-V-L-M-L-V-V-Q-V-A-L-S-Q-H-W-S-Y-G-W-L-P-G-G-K-R-S-V-G-E-L-E-A-T-I-R-M-M-G-T-G-G-V-V-S-L-P-E-E-A-S-A-Q-T-Q-E-R-P-R-P-Y-N-V-I-D-D-G-S-R-H-F-H-R-K-K-R-F-P-D-N"} +{"text": "### FUNCTION Has thioltransferase and dehydroascorbate reductase activities ### SEQUENCE -M-A-E-E-F-V-Q-Q-R-L-A-N-N-K-V-T-I-F-V-K-F-T-C-P-F-C-R-N-A-L-D-I-L-N-K-F-S-F-K-R-G-A-Y-E-I-V-D-I-K-E-F-K-P-E-N-E-L-R-D-Y-F-E-Q-I-T-G-G-R-T-V-P-R-I-F-F-G-K-T-S-I-G-G-Y-S-D-M-L-E-I-D-N-M-D-A-L-G-D-I-L-S-S-I-G-V-L-R-T-C"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-F-N-M-N-I-N-S-P-V-R-F-V-K-E-T-N-R-A-K-S-P-T-R-Q-S-P-Y-A-A-G-Y-D-L-Y-S-A-Y-Y-Y-T-I-P-P-G-E-R-Q-L-I-K-T-D-I-S-M-S-M-P-K-F-C-Y-G-R-I-A-P-R-S-G-L-S-L-K-G-I-D-I-G-G-G-V-I-D-E-D-Y-R-G-N-I-G-V-I-L-I-N-N-G-K-C-T-F-N-V-N-T-G-D-R-I-A-Q-L-I-Y-Q-R-I-Y-Y-P-E-L-K-E-V-Q-S-L-D-S-T-D-R-G-D-Q-G-F-G-S-T-G-L-R"} +{"text": "### FUNCTION Stimulates cellular proliferation and mobility around infected cells to promote rapid and efficient spread of infection ### SEQUENCE -M-S-M-K-Y-L-M-L-L-F-A-T-M-I-I-R-S-F-A-D-S-G-N-A-I-E-T-T-S-P-E-I-T-N-T-T-T-D-I-P-A-I-R-L-C-G-P-E-G-D-G-Y-C-L-H-G-D-C-I-H-A-R-D-I-N-G-M-Y-C-R-C-S-H-G-Y-T-G-I-R-C-Q-H-V-V-L-V-D-Y-Q-R-S-E-K-P-N-T-T-T-S-Y-I-P-S-P-G-I-V-L-V-L-V-G-I-I-M-C-C-L-L-S-V-Y-R-F-T-R-R-T-N-K-L-P-L-Q-D-M-V-V-P"} +{"text": "### FUNCTION May mediate the nuclear export of encapsidated genomic RNAs ### SEQUENCE -M-N-L-L-L-L-L-Q-V-A-S-F-L-S-D-S-K-V-P-G-E-D-G-T-S-S-T-S-G-M-L-D-L-L-R-D-Q-V-D-S-L-S-I-N-D-S-T-T-E-P-K-T-R-L-D-P-G-L-Y-P-W-L-K-W-T-E-T-A-Y-R-S-S-T-R-S-L-A-S-T-I-V-M-G-A-L-V-Q-Q-R-G-S-G-N-G-I-T-M-R-E-L-E-L-S-L-G-L-D-F-T-S-E-C-D-W-L-K-T-C-Y-V-N-K-N-F-V-F-L-S-E-K-E-I-A-V-N-M-E-V-E-K-F-I-C-N-E-N"} +{"text": "### FUNCTION May play a role in inhibition of the host immune system by counteracting the type I interferon response ### SEQUENCE -M-R-E-A-N-P-K-P-R-E-L-I-R-H-A-L-K-K-K-K-R-P-E-V-V-Y-A-M-G-V-L-L-T-L-G-G-E-S-G-L-T-V-E-F-P-V-P-E-G-K-T-V-K-V-K-T-L-N-Q-L-V-N-G-M-I-S-R-A-T-M-T-L-Y-C-V-M-K-D-P-P-S-G-G-M-A-T-L-M-R-D-H-I-R-N-W-L-K-E-E-S-G-C-Q-D-A-D-G-G-E-E-K-W-A-M-V-Y-G-M-I-S-P-D-M-A-E-E-K-T-M-L-K-E-L-K-T-M-L-H-S-R-M-Q-M-Y-A-L-G-A-S-S-K-A-L-E-N-L-E-K-A-I-V-A-A-V-H-R-L-P-A-S-C-S-T-E-K-M-V-L-L-G-Y-L-K"} +{"text": "### FUNCTION Virion protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-V-E-Q-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-R-G-C-D-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-Y-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V"} +{"text": "### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-N-S-L-S-I-F-F-I-V-V-A-T-A-A-V-C-L-L-F-I-Q-S-Y-S-I-Y-E-N-Y-G-N-I-K-E-F-N-A-T-H-A-A-F-E-Y-S-K-S-I-G-G-T-P-A-L-D-R-R-V-Q-D-V-N-D-T-I-S-D-V-K-Q-K-W-R-C-V-V-Y-P-G-N-G-F-V-S-A-S-I-F-G-F-Q-A-E-V-G-P-N-N-T-R-S-I-R-K-F-N-T-M-R-Q-C-I-D-F-T-F-S-D-V-I-N-I-D-I-Y-N-P-C-I-A-P-N-I-N-N-T-E-C-Q-F-L-K-S-V-L"} +{"text": "### FUNCTION Glutaredoxin necessary for virion morphogenesis and virus replication Functions as a thiol-disulfide transfer protein between membrane-associated OPG128 and substrates OPG095 or OPG053 The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves oxidation of OPG072, OPG128 and OPG088 Exhibit thioltransferase and dehydroascorbate reductase activities in vitro ### SEQUENCE -M-K-N-V-L-I-I-F-G-K-P-Y-C-S-I-C-E-N-V-S-E-A-V-E-E-L-K-S-E-Y-D-I-L-H-V-D-I-L-S-F-F-L-K-D-G-D-S-S-M-L-G-D-V-K-R-G-T-L-I-G-N-F-A-A-H-L-S-N-Y-I-V-S-I-F-K-Y-N-P-Q-T-K-Q-M-A-F-V-D-I-N-K-S-L-D-F-T-K-T-D-K-S-L-V-N-L-E-I-L-K-S-E-I-E-K-A-T-Y-G-V-W-P-P-V-T-E"} +{"text": "### FUNCTION Self-assembles to form a helical, filamentous nucleocapsid ### SEQUENCE -M-A-K-G-H-T-S-R-S-Y-S-Q-R-Y-A-K-W-Q-A-K-F-N-A-F-S-N-P-T-V-A-S-T-I-L-S-N-V-S-P-V-A-Q-Q-N-F-Q-T-N-V-P-K-F-T-S-V-N-E-N-V-S-A-V-L-T-Q-Y-G-I-T-G-P-N-R-A-I-Y-Q-G-F-G-L-K-V-A-R-A-L-N-R-I-G-S-G-P-A-L-V-N-M-I-N-G-L-K-G-Y-Y-I-S-A-F-N-A-N-P-Q-V-L-D-A-V-V-N-I-I-T-G-S-P-T-G-Y-V-S"} +{"text": "### FUNCTION Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1 ### SEQUENCE -M-V-A-T-G-S-L-S-S-K-N-T-A-S-I-S-E-L-L-D-G-G-S-H-P-G-S-L-L-S-D-F-D-Y-W-D-Y-V-V-P-E-P-N-L-N-E-V-V-F-E-E-T-T-C-Q-N-L-V-K-M-L-E-N-C-L-S-K-S-K-Q-T-K-L-G-C-S-K-V-L-V-P-E-K-L-T-Q-R-I-A-Q-D-V-L-R-L-S-S-T-E-P-C-G-L-R-G-C-V-M-H-V-N-L-E-I-E-N-V-C-K-K-L-D-R-I-V-C-D-A-S-V-V-P-T-F-E-L-T-L-V-F-K-Q-E-S-C-S-W-T-S-L-K-D-F-F-F-S-G-G-R-F-S-S-G-L-R-R-T-L-I-L-S-S-G-F-R-L-V-K-K-K-L-Y-S-L-I-G-T-T-V-I-E-E-C"} +{"text": "### FUNCTION May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex ### SEQUENCE -M-D-K-L-K-K-V-L-S-G-Q-D-T-E-D-R-S-G-L-S-E-V-V-E-A-S-S-L-S-W-G-T-R-I-K-G-F-I-A-C-F-A-L-G-I-L-C-S-V-L-G-T-L-L-L-W-V-P-R-K-G-L-G-L-F-A-V-F-Y-T-L-G-N-I-M-S-I-G-S-T-V-F-L-M-G-P-L-K-Q-L-K-R-M-F-E-P-T-R-L-I-A-T-I-L-V-L-L-C-F-A-L-T-L-C-S-A-F-L-W-N-K-G-L-A-L-I-F-C-I-L-Q-S-L-A-L-T-W-Y-S-L-S-Y-I-P-Y-A-R-D-A-V-K-K-C-F-A-V-C-L-A"} +{"text": "### FUNCTION Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls and weakly progesterone, potent inhibitor of phospholipase A2 ### SEQUENCE -M-K-I-A-I-T-M-A-V-V-M-L-S-V-C-C-S-S-A-S-S-D-T-C-P-G-F-F-Q-V-L-E-F-L-F-M-G-S-E-S-S-Y-E-A-A-L-K-F-Y-N-P-G-S-D-L-Q-D-S-G-T-Q-L-K-K-L-V-D-T-L-P-Q-K-T-R-M-N-I-M-K-L-S-E-I-I-L-T-S-P-L-C-N-Q-D-L-S-V"} +{"text": "### FUNCTION May be involved in MAP kinase activation, epithelial sodium channel down-regulation and cell cycling ### SEQUENCE -M-G-T-P-A-S-V-V-S-E-P-P-L-W-Q-V-S-T-A-Q-P-R-D-R-G-R-G-R-K-Q-A-S-A-N-I-F-Q-D-A-E-L-V-Q-I-Q-G-L-F-Q-R-S-G-D-Q-L-A-E-E-R-A-Q-I-I-W-E-C-A-G-D-H-R-V-A-E-A-L-R-R-L-R-R-K-R-P-P-R-Q-N-H-C-S-R-L-R-V-P-E-L-G-S-T-A-A-D-P-Q-A-S-T-T-D-T-A-S-S-E-Q-F-G-N-S-R-R-T-S-A-R-V-H-R-N-W-N-K-P-G-P-T-G-Y-L-H-Q-I-R-H"} +{"text": "### FUNCTION Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1 ### SEQUENCE -M-V-A-T-G-S-L-S-S-K-N-P-A-S-I-S-E-L-L-D-G-G-Y-H-P-G-S-L-L-S-D-F-D-Y-W-D-Y-V-V-P-E-P-N-L-N-E-V-V-F-E-E-T-T-C-Q-N-L-V-K-M-L-E-N-C-L-S-R-S-K-Q-T-K-L-G-C-S-K-V-L-V-P-E-K-L-T-Q-R-I-A-Q-D-V-L-R-L-S-S-T-E-P-C-G-L-R-G-C-V-M-H-V-N-L-E-I-E-N-V-C-K-K-L-D-R-I-V-C-D-A-S-V-V-P-T-F-E-L-T-L-V-F-K-Q-E-S-C-P-W-T-S-L-K-D-F-F-F-S-R-G-R-F-S-S-G-L-K-R-T-L-I-L-S-S-G-F-R-L-V-K-K-K-L-Y-S-L-I-G-T-T-V-I-E-E-C"} +{"text": "### FUNCTION May play a specialized role in spermatogenesis ### SEQUENCE -M-S-W-K-V-P-M-L-V-G-L-V-V-L-G-T-H-I-W-T-I-N-K-E-F-L-D-V-T-K-D-L-D-Y-F-V-A-S-V-E-F-A-V-A-Q-F-N-D-N-N-S-E-E-N-T-Y-R-L-L-E-V-G-R-A-Q-K-K-T-W-T-M-I-F-L-M-D-L-E-M-G-R-T-I-C-K-K-H-D-E-N-I-H-N-C-P-L-L-Q-G-S-G-E-K-K-V-H-C-V-F-Q-V-D-A-R-P-W-F-S-H-F-T-V-L-T-S-T-C-V-P-T"} +{"text": "### FUNCTION May play a specialized role in spermatogenesis ### SEQUENCE -M-L-W-K-S-V-L-P-V-A-L-I-V-L-G-I-H-D-C-S-F-K-F-I-E-I-D-K-N-E-E-E-F-A-M-S-M-E-H-V-L-F-H-F-N-E-N-Q-N-D-D-F-A-Y-K-F-L-R-V-R-R-S-L-R-K-K-Y-T-Q-K-Y-L-V-D-L-E-M-G-R-T-L-C-G-K-Y-D-E-D-I-D-N-C-P-L-Q-E-G-P-G-E-K-K-V-R-C-T-Y-I-V-E-T-R-V-W-V-T-E-F-T-I-L-N-S-T-C-V-Q-T"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-K-Q-E-R-Q-R-Y-I-K-R-L-L-S-S-N-E-I-E-R-Q-E-D-F-V-K-L-L-R-A-E-D-I-D-V-T-Q-A-T-I-S-R-D-I-K-D-M-Q-L-V-K-V-P-S-A-T-G-G-Y-H-Y-S-M-P-V-Q-K-Q-M-D-T-E-K-K-L-K-R-T-L-K-D-A-Y-V-S-Y-A-T-Q-D-K-F-V-L-I-K-V-L-P-G-N-G-P-A-L-A-T-L-I-E-A-M-H-Y-D-E-I-F-G-T-L-G-D-D-A-H-V-L-I-I-C-K-S-L-A-M-T-L-E-L-Q-Q-K-I-Q-R-L-L-S-D-H"} +{"text": "### FUNCTION Key component of the KaiABC oscillator complex, which constitutes the main circadian regulator in cyanobacteria Complex composition changes during the circadian cycle to control KaiC phosphorylation KaiA stimulates KaiC autophosphorylation, while KaiB sequesters KaiA, leading to KaiC autodephosphorylation Phospho-Ser-431 KaiC accumulation triggers binding of KaiB to form the KaiB complex that results in KaiC autodephosphorylation ### SEQUENCE -M-V-N-F-K-K-T-Y-V-L-K-L-Y-V-A-G-N-T-P-N-S-V-R-A-L-K-T-L-K-N-I-L-E-D-E-F-K-G-V-Y-A-L-K-V-I-D-V-L-K-N-P-Q-L-A-E-E-D-K-I-L-A-T-P-T-L-S-K-I-L-P-P-P-V-R-K-I-I-G-D-L-S-D-R-E-K-V-L-I-G-L-D-L-L-Y-E-E-I-R-E-R-E-S-E-L"} +{"text": "### FUNCTION Inhibitor of the alkaline protease ### SEQUENCE -M-P-I-L-V-V-L-T-L-M-S-S-G-E-I-M-A-S-S-L-V-L-P-K-V-G-D-L-S-G-Q-W-Q-L-Q-L-N-V-S-G-A-K-I-C-D-I-E-L-K-N-T-P-I-T-P-D-L-I-W-H-A-S-G-D-T-D-C-L-S-Q-L-L-G-S-A-P-Q-G-W-R-P-T-P-D-G-I-M-L-T-D-E-T-G-S-A-V-A-F-F-E-R-A-Q-N-G-Y-E-N-T-L-P-D-D-A-G-V-I-V-L-R-R-V-Q-E"} +{"text": "### FUNCTION Structural component of flagellum, the bacterial motility apparatus Part of the rod structure of flagellar basal body ### SEQUENCE -M-T-G-F-R-D-Q-L-G-V-H-A-Q-A-L-V-L-R-E-T-R-N-N-L-L-T-S-N-I-A-N-A-A-T-P-H-Y-K-A-R-D-I-D-F-G-A-E-L-A-R-A-S-G-N-G-T-V-R-T-T-E-A-R-H-F-A-A-G-G-P-A-A-R-G-E-A-L-Y-R-D-P-V-S-P-S-L-D-G-N-T-V-E-M-A-V-E-Q-M-E-F-A-E-N-T-L-R-Y-Q-T-S-L-A-L-L-N-R-R-I-S-G-L-M-T-A-I-K-G-E"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-G-P-L-G-F-V-A-V-G-V-G-A-A-A-G-A-W-L-R-W-G-F-A-V-L-W-N-A-I-N-P-A-L-P-Y-G-T-L-A-A-N-L-L-G-G-Y-L-V-G-L-A-V-G-F-F-D-T-H-A-G-L-P-P-E-W-R-L-L-A-I-T-G-F-L-G-G-L-T-T-F-S-T-F-S-S-E-V-V-A-N-L-I-A-G-D-Y-G-W-A-G-L-H-L-L-L-H-L-G-G-S-L-L-L-T-A-F-G-L-W-T-Y-R-L-L-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-N-R-A-E-K-R-D-V-L-A-D-P-I-Y-N-S-K-L-V-T-R-A-I-N-K-I-M-L-D-G-K-R-G-I-A-Q-S-I-I-Y-D-A-F-N-I-I-K-E-K-T-N-K-E-P-I-E-V-F-N-K-A-I-E-N-I-K-P-H-L-E-L-K-V-R-R-I-G-G-A-N-Y-Q-V-P-I-E-V-S-A-E-R-Q-I-T-L-A-L-R-W-L-I-N-Y-A-R-L-R-N-E-K-V-M-T-I-K-L-A-N-E-I-I-D-A-S-N-N-I-G-G-S-V-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site ### SEQUENCE -M-A-F-E-L-P-K-L-P-Y-A-F-D-A-L-E-P-H-I-D-K-E-T-M-E-I-H-H-D-K-H-H-N-T-Y-V-T-K-L-N-A-V-V-E-G-T-D-L-E-A-K-S-I-E-E-I-V-A-N-L-D-S-V-P-S-D-I-Q-T-A-V-R-N-N-G-G-G-H-L-N-H-S-L-F-W-E-L-L-T-P-N-S-E-E-K-G-E-V-V-E-K-I-K-E-Q-W-G-S-L-D-E-F-K-K-E-F-A-D-K-A-A-A-R-F-G-S-G-W-A-W-L-V-V-N-N-G-Q-L-E-I-V-T-T-P-N-Q-D-N-P-L-T-E-G-K-T-P-I-L-G-L-D-V-W-E-H-A-Y-Y-L-K-Y-Q-N-K-R-P-D-Y-I-S-A-F-W-N-V-V-N-W-E-K-V-D-E-L-Y-N-A-A-K"} +{"text": "### FUNCTION Inhibits all catalytic activities of RNA polymerase by partially occluding its substrate-binding site and preventing NTP binding ### SEQUENCE -M-A-R-E-V-K-L-T-K-A-G-Y-E-R-L-M-K-Q-L-E-Q-E-R-E-R-L-Q-E-A-T-K-I-L-Q-E-L-M-E-S-S-D-D-Y-D-D-S-G-L-E-A-A-K-Q-E-K-A-R-I-E-A-R-I-D-S-L-E-D-V-L-S-R-A-V-I-L-E-E-G-T-G-E-V-I-G-L-G-S-V-V-E-L-E-D-P-A-T-G-E-R-L-S-V-Q-V-V-S-P-A-E-A-S-V-L-E-N-P-M-K-I-S-D-A-S-P-M-G-K-A-L-L-G-H-R-V-G-D-V-L-S-L-D-T-P-K-G-K-K-E-F-R-V-V-A-I-H-G-R"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-D-E-A-R-G-G-P-D-K-K-K-E-R-G-P-K-R-P-R-K-V-S-P-T-Y-L-E-N-A-A-L-H-Y-L-K-R-Y-A-A-T-K-S-Q-L-Q-R-V-L-L-R-R-V-D-R-S-I-K-F-H-G-G-E-R-G-E-A-L-A-W-V-E-A-L-V-A-K-L-V-R-N-G-L-L-N-D-E-A-Y-A-Q-M-K-A-H-S-L-R-A-S-G-R-S-T-R-V-I-A-Q-K-L-R-L-K-G-V-P-A-E-V-V-A-K-K-V-A-D-A-T-H-E-V-S-E-E-D-A-A-R-I-W-A-R-K-K-R-L-G-P-F-R-T-Q-P-G-T-R-E-E-N-R-K-R-D-L-A-A-L-A-R-A-G-F-S-F-G-I-A-K-K-V-I-D-S-N-P-A"} +{"text": "### FUNCTION Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane Generates a proton motive force ### SEQUENCE -N-G-S-I-M-G-A-L-Y-K-G-L-I-A-T-G-L-L-S-I-V-G-L-G-V-A-N-T-L-T-V-G-W-G-E-I-G-T-V-A-G-K-S-I-T-G-T-N-L-F-V-C-G-L-I-G-L-I-V-T-G-L-I-V-V-I-T-E-Y-Y-T-G-T-N-K-R-P-V-N-S-X-A-Q-A-S-V-T-G-H-G-T-N-V-I-Q-G-L-A-V-S-L-E-S-T-A-L-P-A-I-V-I-V-G-G-I-I-X-T-Y-Q-L-A-G-L-F-G-T-A-I-A-V-T-A-M-L-G-I-A-G-M-I"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-T-G-K-Q-I-L-N-E-A-K-D-K-M-A-K-S-G-D-A-L-R-R-T-L-A-D-I-R-A-G-R-A-N-A-S-L-L-N-G-V-K-V-D-Y-Y-G-A-P-T-P-L-N-Q-V-A-S-I-T-I-P-E-A-R-Q-L-L-V-T-P-Y-D-E-S-S-L-D-N-I-E-K-A-I-Y-A-A-N-L-G-L-T-P-Q-N-D-G-S-A-I-R-I-L-I-P-Q-L-T-E-E-R-R-K-E-L-V-K-D-V-K-A-E-L-E-K-A-K-V-A-V-R-N-V-R-R-E-A-M-D-D-L-K-K-G-N-K-D-G-D-F-N-D-D-E-F-H-D-L-E-K-K-V-Q-T-E-T-D-N-G-I-K-N-L-E-N-I-A-A-D-K-E-K-E-L-M-G"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-I-E-E-K-E-E-K-V-G-G-F-V-I-A-G-N-S-H-A-A-T-K-T-A-A-V-V-A-V-G-Q-G-V-R-T-L-T-G-E-L-V-A-P-S-V-K-A-G-D-K-V-L-V-E-S-H-A-G-V-E-V-K-D-G-E-E-T-Y-L-L-V-S-E-A-N-I-L-A-I-V-E"} +{"text": "### FUNCTION Modulates transcription in response to changes in cellular NADH/NAD redox state ### SEQUENCE -A-S-S-K-E-I-A-E-A-I-G-I-D-S-A-T-V-R-R-D-F-S-Y-F-G-E-L-G-R-R-G-F-G-Y-N-V-K-E-L-M-D-F-F-A-D-I-L-N-D-T-S-I-T-N-V-M-L-V-G-V-G-N-M-G-R-A-L-L-H-Y-R-F-H-E-R-N-K-M-K-I-V-M-A-F-E-A-D-D-N-P-A-V-G-T-T-D-E-N-I-P-I-H-A-I-S-E-I-K-E-R-I-S-E-A-N-S-Q-T-A-I-L-T-V-P-S-V-K-A-Q-E-V-T-D-I-L-V-E-A-G-V-K-G-I-L-S-F-S-P-V-N-L-S-V-P-K-D-V-V-V-Q-Y-V-D-L-T-S-E-L-Q-T-L-L-Y-F-M-R-K-G"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-T-I-L-A-V-G-K-L-K-E-K-Y-W-K-Q-A-I-A-E-Y-E-K-R-L-G-A-Y-S-K-I-E-M-I-E-V-P-D-E-K-A-P-E-T-M-S-D-K-E-I-E-K-V-K-E-K-E-G-Q-R-L-L-A-Q-I-K-P-Q-A-T-V-I-T-L-E-I-Q-G-K-M-L-S-S-E-G-L-A-K-E-L-Q-Q-R-M-T-Q-G-Q-S-D-F-V-F-V-I-G-G-S-N-G-L-H-Q-D-V-L-N-R-S-N-Y-A-L-S-F-S-K-M-T-F-P-H-Q-M-M-R-V-V-L-I-E-Q-V-Y-R-A-F-K-I-M-R-G-E-A-Y-H-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-L-L-T-V-N-L-N-V-V-S-A-E-E-S-L-F-S-G-S-I-K-S-L-Q-I-T-G-S-E-G-E-L-G-I-M-P-G-H-A-P-L-L-T-S-L-K-P-G-M-A-L-I-T-K-K-D-G-S-E-E-V-I-Y-L-S-G-G-M-L-E-V-Q-P-N-N-V-T-V-L-A-D-I-A-T-R-A-A-D-L-D-E-Q-A-A-L-E-A-K-Q-R-A-E-E-N-M-N-A-N-G-A-D-V-D-F-A-V-A-A-A-Q-L-A-R-A-V-A-Q-L-R-V-I-Q-A-T-S-K-H-N"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-I-K-P-L-G-D-R-V-V-I-E-I-V-E-T-E-E-K-T-A-S-G-I-V-L-P-D-T-A-K-E-K-P-Q-E-G-K-V-V-A-V-G-K-G-R-V-L-D-N-G-Q-R-V-A-P-E-V-E-V-G-D-R-I-I-F-S-K-Y-A-G-T-E-V-K-Y-D-G-K-E-Y-L-I-L-R-E-S-D-I-L-A-V-I-G"} +{"text": "### FUNCTION N-acyltransferase required for nodulation Acts in the production of a small, heat-stable compound that stimulates mitosis in various plant protoplasts ### SEQUENCE -M-C-S-R-V-R-W-T-L-R-W-E-S-E-L-Q-L-D-D-H-V-E-L-A-S-F-F-R-K-T-Y-G-P-T-G-A-F-N-A-K-P-F-E-G-S-R-S-W-A-G-A-R-P-E-L-R-A-I-A-Y-D-S-N-G-V-A-A-H-M-G-L-L-R-R-F-I-K-V-G-E-V-D-L-L-V-A-E-L-G-L-Y-G-V-R-P-D-L-E-G-L-G-I-S-H-S-L-R-V-M-Y-P-V-L-Q-Q-L-R-V-P-F-G-F-G-A-V-R-H-A-L-Q-K-H-V-E-R-F-G-R-H-V-P-A-N-V-L-S-G-I-R-V-R-S-T-L-P-D-A-R-L-D-L-P-P-T-R-I-E-D-V-L-V-V-V-F-P-V-E-L-A-M-S-D-W-P-T-A-T-F-I-D-R-N-G-P-E-L"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-I-K-T-G-G-K-Q-Y-R-V-A-A-N-D-L-I-K-V-E-K-V-A-G-E-A-G-D-I-V-E-F-A-E-V-L-M-V-G-S-T-I-G-A-P-T-V-A-G-S-L-V-T-A-E-V-V-E-Q-G-R-G-R-K-V-I-A-F-K-K-R-R-R-Q-N-S-K-R-T-R-G-H-R-Q-E-L-T-T-I-R-I-S-E-I-L-T-D-G-A-K-P-S-K-K-A-A-E-K-K-A-P-K-A-D-A-A-E-G-E-A-A-K-P-K-K-A-A-P-K-K-A-A-T-K-A-E-S-A-E"} +{"text": "### FUNCTION This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport ### SEQUENCE -M-G-G-G-R-V-A-H-P-V-L-K-G-P-S-V-V-K-E-L-V-I-G-T-V-L-G-L-A-A-G-G-L-W-K-M-H-H-W-N-E-Q-R-K-T-R-A-F-Y-D-L-L-E-K-G-E-I-S-V-V-V-D-E-E"} +{"text": "### FUNCTION This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport ### SEQUENCE -M-V-G-G-R-V-A-H-P-V-L-K-G-P-S-E-V-K-E-L-I-I-G-S-V-L-G-L-A-A-G-G-L-W-K-M-H-H-W-N-E-Q-R-K-T-R-A-F-Y-D-L-L-E-K-G-E-I-S-V-V-V-Q-E"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-S-K-D-G-L-S-N-D-Q-V-S-S-M-K-E-A-F-M-L-F-D-T-D-G-D-G-K-I-A-P-S-E-L-G-I-L-M-R-S-L-G-G-N-P-T-E-S-Q-L-K-S-I-I-T-T-E-N-L-S-S-P-F-D-F-N-R-F-L-D-L-M-A-K-H-L-K-T-E-P-F-D-R-Q-L-R-D-A-F-K-V-L-D-K-E-G-T-G-F-V-A-V-A-D-L-R-H-I-L-T-S-I-G-E-K-L-Q-P-S-E-F-D-E-W-I-K-E-V-D-V-G-S-D-G-K-I-R-Y-E-D-F-I-A-R-M-V-A-K"} +{"text": "### FUNCTION Component of the ESCRT-II complex ### SEQUENCE -M-Q-K-L-A-D-F-K-L-P-Q-F-F-N-Y-P-P-Y-F-T-L-Q-P-V-R-D-T-R-E-K-Q-I-Q-L-W-K-E-L-I-L-D-Y-C-K-S-Q-K-I-F-L-I-G-V-E-E-D-F-P-L-F-S-N-S-A-I-D-R-S-L-S-H-E-A-R-E-T-F-L-S-A-I-V-G-E-G-R-A-E-W-L-D-K-G-H-R-K-C-L-I-L-W-H-R-I-Q-D-W-A-D-I-V-L-Q-F-V-R-D-N-G-L-E-D-S-V-M-T-V-E-E-I-R-S-G-T-E-S-L-G-T-E-L-Q-G-I-D-R-T-I-L-M-R-A-L-K-L-L-E-N-K-G-K-L-A-L-F-K-G-T-S-A-D-D-E-G-V-K-F-S-V"} +{"text": "### FUNCTION Thionins are small plant proteins which are toxic to animal cells They seem to exert their toxic effect at the level of the cell membrane Their precise function is not known ### SEQUENCE -M-E-G-K-T-V-I-F-S-V-L-V-M-G-L-V-I-S-Q-I-Q-V-E-A-Q-K-T-C-C-P-S-Q-S-T-R-K-E-F-E-D-C-I-S-E-G-N-L-Q-I-L-C-S-A-E-S-G-C-R-D-T-Y-V-G-Y-C-P-S-G-F-P-Y-G-S-L-T-N-S-G-D-V-V-N-V-Y-C-K-L-G-C-V-S-S-L-C-G-A-L-T-S-L-Q-K-L-D-T-S-G-K-V-N-V-A-V-E-R-C-T-K-A-C-S-T-I-C-T-K-G-S-K-T-A-V-E-T-V"} +{"text": "### FUNCTION Probably acts as a transcriptional activator Binds to the GCC-box pathogenesis-related promoter element May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways ### SEQUENCE -M-V-I-Q-Y-K-R-K-Q-E-F-P-M-V-K-E-G-M-V-M-T-E-K-P-K-R-N-L-I-S-S-N-E-K-R-Y-K-G-I-R-M-R-K-W-G-K-W-V-A-E-I-R-E-P-N-K-R-S-R-I-W-L-G-S-Y-K-T-A-V-A-A-A-R-A-Y-D-T-A-V-F-Y-L-R-G-P-S-A-R-L-N-F-P-E-E-V-F-K-D-G-N-G-G-E-G-L-G-G-D-M-S-P-T-L-I-R-K-K-A-A-E-V-G-A-R-V-D-A-E-L-R-L-E-N-R-M-V-E-N-L-D-M-N-K-L-P-E-A-Y-G-L"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-I-Q-Q-L-I-R-N-A-R-Q-P-I-R-S-R-T-K-S-P-A-L-R-G-C-P-Q-R-R-G-V-C-I-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-I-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-S-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-A-V-G-V-K-D-R-K-Q-G-R-S-R-Y-G-V-K-K-P-K"} +{"text": "### FUNCTION This protein binds to 23S rRNA ### SEQUENCE -M-G-T-Y-A-I-I-E-T-G-G-E-Q-L-R-V-E-P-G-R-F-Y-D-A-R-C-F-A-S-L-N-P-R-I-L-S-A-N-A-K-I-L-I-H-R-V-L-M-I-R-R-E-S-T-T-N-L-G-H-P-W-L-R-N-A-I-V-R-G-R-I-L-H-S-C-Y-G-E-K-I-T-I-Y-K-M-H-S-K-K-K-V-R-R-K-L-G-Y-R-Q-K-L-V-R-F-V-V-D-S-I-S-S-N-G-E-E-F-F-D"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-N-E-I-K-N-Q-I-I-T-E-K-T-I-R-L-L-Q-K-N-Q-Y-T-F-N-V-D-S-K-L-T-K-T-K-I-K-D-W-I-E-R-F-F-D-V-K-V-K-S-I-N-S-L-R-S-P-R-K-K-S-Q-K-R-L-P-Q-T-S-L-N-D-K-R-M-I-I-T-L-K-P-E-Y-S-I-P-L-F-I-N-E"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-L-K-K-V-P-F-V-A-H-H-L-W-K-K-I-E-S-L-N-I-K-K-E-K-R-V-I-I-T-W-S-R-A-S-T-I-V-P-G-M-I-G-H-T-I-A-V-Y-N-G-R-E-H-L-P-I-Y-V-T-D-R-M-V-G-H-K-L-G-E-F-V-L-T-R-T-F-R-G-H-A-R-K-D-K-K-S-R-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-K-K-K-E-V-R-A-L-A-K-Y-V-K-M-S-A-H-K-V-R-R-V-I-N-Q-I-R-G-R-S-Y-E-E-A-L-I-S-L-E-F-L-P-Y-R-A-C-Y-P-L-L-Q-L-V-S-S-A-A-A-N-A-N-N-N-L-G-L-K-K-D-T-L-L-I-S-E-A-K-V-D-E-A-S-V-S-K-R-F-Q-P-R-A-Q-G-R-A-Y-S-I-Q-K-D-T-C-H-I-T-I-K-I-R-E-R-S-K"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-P-Q-S-Y-L-K-V-T-D-N-S-G-A-R-K-L-M-C-I-R-I-L-G-T-N-N-C-K-Y-A-N-T-G-D-T-I-I-A-V-V-K-E-S-V-P-N-M-P-V-K-K-S-E-I-V-R-A-V-I-V-R-T-R-K-E-M-K-R-D-N-G-I-I-I-R-F-D-D-N-A-A-V-V-I-N-R-E-G-N-L-K-G-T-R-V-H-G-P-V-D-R-E-L-W-K-K-N-F-T-K-I-V-S-L-A-P-E-A-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-H-D-T-I-A-D-M-I-S-L-V-R-N-A-N-M-R-K-A-V-K-V-R-V-P-A-T-G-I-T-Q-N-I-V-K-I-L-L-Q-E-G-F-I-K-D-Y-M-K-Q-E-K-R-T-R-S-F-F-I-L-T-L-K-Y-Q-G-R-V-R-K-P-H-I-T-A-F-K-R-I-S-K-P-S-L-R-I-Y-S-N-Y-Q-K-I-T-R-I-L-G-G-M-G-I-A-I-I-S-T-S-S-G-I-M-T-D-R-E-A-R-Q-K-R-L-G-G-E-I-I-C-H-V-W"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-H-D-L-I-N-M-E-G-I-V-T-E-S-L-P-N-A-M-F-R-V-F-L-D-N-G-C-H-V-L-T-H-I-S-G-K-I-R-R-N-Y-I-R-I-L-P-G-D-R-V-K-V-E-L-S-I-Y-D-L-T-K-G-R-I-L-Y-R-I-R-N-E-A-S-K-D-T-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-G-V-T-K-K-P-D-L-N-D-P-V-S-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-I-V-I-L-G-T-I-A-C-I-A-G-L-A-V-L-E-P-S-M-I-G-E-P-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-Y-P-V-F-Q-I-L-R-T-V-P-N-K-L-L-G-V-L-L-M-A-S-V-P-A-G-L-L-T-V-P-F-L-E-N-V-N-K-F-Q-N-P-F-R-R-P-V-A-T-T-V-F-L-I-G-T-V-V-A-I-W-L-G-I-G-A-A-L-P-I-D-R-S-L-T-L-G-L-F"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-I-A-I-F-I-S-C-L-I-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-K-E-L-R-D-P-F-E-E-H-E-D"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-V-K-R-G-Y-V-A-R-R-H-R-N-R-I-L-A-L-T-S-G-F-Q-G-A-H-S-K-L-F-R-T-A-N-Q-Q-G-M-K-A-L-T-Y-A-Y-R-D-R-A-N-C-K-R-D-F-R-R-L-W-I-T-R-I-N-A-A-A-R-E-N-Q-I-T-Y-N-N-M-I-H-S-L-Y-M-N-Q-I-H-L-N-R-K-I-L-A-Q-I-A-A-L-D-K-D-C-F-V-E-I-L-R-I-I-K"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-Q-D-V-K-T-Y-L-S-T-A-P-V-L-A-T-L-W-F-G-F-L-A-G-L-L-I-E-I-N-R-F-F-P-D-A-L-V-S-P-L-F"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-V-E-A-L-L-S-G-I-V-L-G-L-I-S-I-T-S-A-G-L-F-V-T-A-Y-L-Q-Y-R-R-G-D-Q-L-D-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex ### SEQUENCE -M-L-T-L-L-S-Y-F-G-L-L-L-A-A-L-I-S-T-L-V-L-F-I-G-L-N-K-V-K-L-I"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-N-T-T-G-R-I-P-L-W-L-V-G-T-V-T-G-T-L-V-I-G-L-M-G-I-F-F-Y-G-A-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-K-R-Q-S-E-W-I-R-V-E-S-I-R-G-A-R-R-I-S-N-F-F-W-A-F-I-L-I-L-G-A-L-G-F-L-L-V-G-S-S-S-Y-L-G-R-D-L-I-P-L-L-P-S-Q-Q-I-V-F-I-P-Q-G-I-V-M-C-F-Y-G-I-A-G-I-S-I-G-F-Y-L-G-F-A-I-S-W-D-I-G-N-G-Y-N-L-F-D-K-Q-R-G-I-V-R-I-F-R-W-G-F-P-G-E-N-R-R-I-C-I-Q-F-F-M-K-D-I-Q-A-I-G-L-E-I-R-E-G-F-Y-S-R-R-I-I-Y-M-R-M-K-G-Q-Q-K-I-F-L-T-H-I-S-E-N-S-T-L-K-E-M-E-E-K-A-A-N-L-A-R-F-M-C-V-S-I-E-G-I"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-T-A-S-Y-L-P-S-I-F-V-P-L-V-G-L-V-F-P-A-I-T-M-A-S-L-F-I-Y-I-E-Q-D-E-I-V"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-L-N-L-R-V-I-A-P-N-R-I-V-W-N-S-E-V-R-E-I-I-L-S-T-N-N-G-Q-M-G-I-L-P-N-H-A-P-L-L-T-A-L-D-I-G-V-M-K-I-R-I-D-E-R-W-S-N-M-A-L-M-G-G-F-A-T-I-D-N-N-Q-I-T-I-L-V-N-E-A-E-K-S-S-E-I-D-P-E-E-A-Q-E-T-F-Q-K-A-Q-A-N-L-T-R-A-E-G-K-R-K-T-I-E-A-H-L-A-F-K-R-A-K-A-R-L-E-A-I-N-V-T-Q-E"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-Q-R-N-D-N-F-I-D-K-T-F-T-I-A-A-D-I-L-L-R-V-I-P-T-T-R-R-E-K-E-A-F-T-Y-Y-R-D-G-M-S-A-Q-S-E-G-E-Y-A-E-A-L-Q-N-Y-Y-K-A-M-R-L-E-I-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-E-H-A-K-A-L-E-Y-Y-F-Q-A-L-E-R-N-P-S-L-P-Q-A-F-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-Q-Q-G-D-P-G-T-S-E-I-W-F-D-K-A-A-E-Y-W-K-Q-A-I-A-L-A-P-N-N-Y-I-E-A-Q-N-W-L-R-I-T-G-R-S-E-D-W-E"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-K-K-S-L-I-E-R-E-K-K-R-K-K-L-V-Q-E-Y-N-S-I-R-K-L-L-K-E-E-I-K-K-A-S-S-L-K-E-K-W-E-I-H-K-K-S-Q-I-L-P-R-N-S-A-P-T-R-L-H-R-R-C-S-L-T-G-R-S-R-S-N-Y-R-D-F-G-L-C-R-H-V-L-R-E-M-A-H-T-C-S-L-P-G-V-T-K-S-S-W"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -M-T-I-A-F-E-L-S-V-F-A-L-I-T-I-S-F-L-L-V-I-G-V-P-V-V-L-A-S-P-D-G-W-S-S-S-K-N-I-V-F-S-G-A-S-L-W-I-G-L-V-F-L-V-G-I-L-N-S-L-I-S"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-S-I-P-T-A-F-L-L-I-P-Y-V-Q-T-A-T-Q-S-N"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-T-V-S-I-A-W-A-A-L-M-V-I-F-T-F-S-I-S-L-V-V-W-G-R-N-G-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-I-N-A-I-N-L-P-I-S-L-N-N-G-P-P-A-G-G-F-G-L-N-T-N-I-F-E-I-N-I-I-N-L-G-I-V-I-G-L-L-V-Y-L-G-E-G-V-L-T-N-L-L-V-N-R-K-Q-T-I-L-S-T-I-R-D-A-E-E-R-Y-R-E-A-T-D-K-L-K-Q-A-R-A-R-L-Q-Q-A-K-V-K-A-G-E-I-R-S-N-G-L-A-R-M-E-R-E-K-Q-D-L-I-N-A-A-D-E-D-S-K-R-L-E-E-S-K-N-S-T-I-R-F-E-E-Q-R-A-I-E-Q-V-R-Q-Q-V-S-R-L-A-L-E-R-V-L-E-S-L-K-S-R-F-N-S-E-L-H-S-R-M-I-D-Y-H-I-D-L-I-K-S-M-E-G-T-T-D"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-T-W-E-L-I-A-Q-L-T-F-L-T-S-I-I-V-S-G-P-L-V-I-A-L-L-A-I-R-K-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-L-F-V-Y-T-V-V-I-L-F-I-S-L-F-V-F-G-F-L-S-N-D-P-G-R-N-P-G-R-K-E"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-V-I-S-N-V-Y-P-S-N-L-F-T-L-I-N-P-F-F-A-K-L-P-E-A-Y-A-I-F-D-P-I-V-D-V-M-P-I-I-P-V-F-F-F-L-L-A-F-V-W-Q-A-A-V-S-F-R"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-P-Q-T-L-L-N-V-A-D-N-S-G-A-R-E-L-M-C-I-R-I-I-G-A-S-N-R-R-Y-A-H-I-G-D-V-I-V-A-V-I-K-K-A-V-P-N-T-P-L-E-R-S-E-V-I-R-A-V-I-V-R-T-C-K-E-L-K-R-E-N-G-M-I-I-R-Y-D-D-N-A-A-V-V-I-D-Q-E-G-N-P-K-G-T-R-I-F-G-A-I-A-R-E-L-R-Q-L-N-F-T-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-R-S-R-C-R-R-R-R-R-R-C-Y-R-R-R-R-R-C-C-R-R-R-R-R-R-V-C-C-R-R-Y-T-V-I-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-R-C-R-S-R-S-R-C-R-R-R-R-R-R-C-H-R-R-R-R-R-C-C-R-R-R-R-R-R-R-A-C-C-R-R-Y-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-P-S-R-S-R-C-R-R-R-R-R-R-C-R-R-R-R-R-R-C-C-R-R-R-R-R-V-C-C-R-R-Y-T-V-R-C-R-R-R"} +{"text": "### FUNCTION May be signaling molecules that resemble neuropeptides Ligand for alpha-neurexins ### SEQUENCE -V-P-P-T-K-I-V-E-F-D-L-A-Q-Q-T-V-I-D-A-K-D-S-K-S-F-N-C-R-I-E-Y-E-K-V-D-K-A-T-K-N-T-L-C-N-Y-D-P-S-K-T-C-Y-Q-E-Q-T-Q-S-H-V-S-W-L-C-S-K-P-F-K-V-I-C-I-Y-I-S-F-Y-S-T-D-Y-K-L-V-Q-K-V-C-P-D-Y-N-Y-H-S-D-T-P-Y-F-P-S-G"} +{"text": "### FUNCTION May be signaling molecules that resemble neuropeptides Ligand for alpha-neurexins ### SEQUENCE -N-A-T-G-Q-G-N-I-S-I-S-L-V-P-P-S-K-A-V-E-X-H-Q-X-Q-Q-I-F-I-E-A-K-A-S-K-I-F-N-C-R-M-E-W-E-K-V-E-R-G-R-R-T-S-L-C-T-H-D-P-A-K-I-C-S-R-D-H-A-Q-S-S-A-T-W-S-C-S-Q-P-F-K-V-V-C-V-Y-I-A-F-Y-S-T-D-Y-R"} +{"text": "### FUNCTION May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors ### SEQUENCE -N-C-H-V-E-Y-E-K-T-N-R-A-R-K-H-R-P-C-L-Y-D-P-S-Q-V-C-F-T-E-H-T-Q-S-Q-A-A-W-L-C-A-K-P-Y-K-V-I-C-I-F-V-S-F-L-S-F-D-Y-K-L-V-Q-K-V-C-P-D-Y-N-F-Q-S-E-H-P-Y-F-G"} +{"text": "### FUNCTION Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids ### SEQUENCE -M-E-M-F-Q-G-L-L-L-W-L-L-L-N-T-G-G-A-W-A-S-R-G-P-L-R-P-L-C-R-P-I-N-A-T-L-A-A-E-N-E-A-C-P-V-C-I-T-F-T-T-T-I-C-A-G-Y-C-P-S-M-V-R-V-L-P-A-A-L-P-P-V-P-Q-P-V-C-T-Y-H-E-L-R-F-A-S-I-R-L-P-G-C-P-P-G-V-D-P-M-V-S-F-P-V-A-L-S-C-R-C-G-P-C-R-L-S-N-S-D-C-G-G-P-R-A-Q-P-L-A-C-D-R-P-P-L-P-G-L-L-F-L"} +{"text": "### FUNCTION This is an intracellular thiol proteinase inhibitor ### SEQUENCE -M-I-P-G-G-L-S-E-A-K-P-A-T-P-E-I-Q-E-I-A-N-E-V-K-P-Q-L-E-E-K-T-N-E-T-Y-Q-K-F-E-A-I-E-Y-K-T-Q-V-V-A-G-I-N-Y-Y-I-K-V-Q-V-D-D-N-R-Y-I-H-I-K-V-F-K-G-L-P-V-Q-D-S-S-L-T-L-T-G-Y-Q-T-G-K-S-E-D-D-E-L-T-G-F"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-R-S-R-C-R-R-R-R-R-R-C-H-R-R-R-R-R-C-S-R-R-R-R-R-R-V-C-C-R-R-Y-T-V-I-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-R-S-R-C-R-R-R-R-R-R-C-Y-R-R-R-R-R-C-C-R-R-R-R-R-R-R-V-C-C-R-R-Y-S-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-R-S-R-C-R-R-R-R-R-R-S-Y-R-R-R-R-R-C-C-R-R-R-R-R-R-V-C-C-R-R-Y-V-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-R-R-R-R-R-R-C-Y-R-R-R-R-R-C-C-R-R-R-R-R-R-V-C-C-R-R-Y-T-R-Y-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-R-R-R-R-R-R-C-Y-R-R-R-R-R-C-C-R-R-R-R-R-R-V-C-C-R-R-Y-T-V-V-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-R-S-R-S-R-C-R-R-R-R-R-K-C-Y-R-R-R-R-R-C-S-R-K-R-R-R-R-V-C-C-R-R-Y-T-V-M-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-R-P-R-R-R-R-C-R-T-R-R-R-R-C-C-R-R-R-R-R-R-V-C-C-R-R-Y-T-V-V-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-R-R-R-R-R-R-C-R-T-R-R-R-R-C-C-R-R-R-R-R-R-V-C-C-R-R-Y-T-V-V-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-P-S-R-S-R-C-R-R-R-R-R-R-C-R-R-R-R-R-R-S-C-R-R-R-R-R-V-C-C-R-R-Y-T-V-R-C-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-R-S-R-S-R-C-R-P-R-R-R-R-C-R-R-R-R-R-R-C-C-R-R-R-R-R-V-C-C-R-R-Y-S-A-R-C-R-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-S-C-C-R-S-H-S-R-S-R-S-R-R-R-R-Q-R-C-R-R-R-R-R-R-S-C-G-R-R-R-R-A-C-Y-R-R-Y-T-V-R-Y-R-R-R-R-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-H-S-R-S-R-C-R-R-R-R-R-R-S-R-R-R-R-R-R-S-C-G-R-R-R-R-A-G-Y-R-R-Y-T-V-R-Y-R-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-R-R-R-R-R-R-C-R-R-R-R-R-R-C-C-R-R-R-R-R-V-C-C-R-R-Y-T-V-R-C-R-R-R-R"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-R-S-R-C-R-R-R-R-R-S-C-R-R-R-R-R-C-R-R-R-R-A-R-R-S-C-R-R-R-Y-S-L-R-C-C-R-R-Y"} +{"text": "### FUNCTION Colony queen number, a major feature of social organization, is associated with worker genotype for Gp-9 Colonies are headed by either a single reproductive queen ### SEQUENCE -M-K-T-F-V-L-H-I-F-I-F-A-F-V-A-F-A-S-A-S-R-D-S-A-K-K-I-G-S-Q-Y-D-N-Y-E-T-C-L-T-E-H-G-L-T-D-D-D-I-F-S-I-G-E-V-S-S-G-Q-H-K-T-N-H-E-D-T-E-L-H-K-N-G-C-V-M-Q-C-M-L-E-K-D-G-L-M-S-G-A-D-Y-D-E-E-K-M-R-E-D-Y-I-K-E-T-G-A-Q-P-G-D-Q-R-I-E-A-L-N-T-C-M-Q-E-T-K-D-M-E-D-K-C-D-K-S-L-I-L-V-A-C-V-L-A-A-E-A-V-L-A-D-S-S-E-G-A"} +{"text": "### FUNCTION Colony queen number, a major feature of social organization, is associated with worker genotype for Gp-9 Colonies are headed by either a single reproductive queen ### SEQUENCE -M-K-T-F-V-F-H-I-F-I-F-A-L-V-A-F-A-S-A-S-R-D-S-A-K-K-I-G-S-Q-Y-E-H-Y-A-T-C-L-T-E-N-D-A-A-A-D-D-I-F-T-I-L-D-I-T-S-G-H-H-K-N-E-N-E-H-D-K-Q-H-K-N-G-C-V-M-H-C-L-L-E-K-D-G-L-M-T-G-A-D-Y-H-E-E-K-I-R-E-D-Y-I-K-E-T-G-A-Q-P-G-D-K-R-L-E-A-L-D-T-C-M-N-E-T-K-D-M-T-D-K-C-D-K-S-L-L-L-V-A-C-V-L-I-A-E-D-S-L-A-T-S-T-E-A-S-T-E-A"} +{"text": "### FUNCTION Colony queen number, a major feature of social organization, is associated with worker genotype for Gp-9 Colonies are headed by either a single reproductive queen ### SEQUENCE -M-K-T-F-V-L-H-I-F-I-F-A-L-V-A-F-A-S-A-S-R-D-S-A-K-K-I-G-S-Q-Y-D-N-Y-E-T-C-L-T-E-H-G-L-T-D-D-D-I-F-S-I-G-E-V-S-S-G-Q-H-K-T-N-H-E-D-T-E-L-H-K-N-G-C-V-L-Q-C-M-L-E-K-D-G-L-M-S-G-A-D-Y-D-E-E-K-M-R-E-D-Y-I-K-E-T-G-T-E-P-G-D-Q-R-I-E-A-L-N-A-C-M-Q-E-T-K-D-M-E-D-K-C-D-K-S-L-L-L-V-A-C-V-L-A-A-E-A-V-L-A-D-S-N-E-G-A"} +{"text": "### FUNCTION Binds retinol and different fatty acids ### SEQUENCE -M-Y-H-R-L-I-L-L-A-L-I-G-T-T-M-A-N-V-I-P-F-S-M-S-T-I-P-E-E-Y-K-E-F-I-P-E-E-V-R-N-F-Y-K-D-L-T-V-E-D-K-E-I-L-R-E-L-A-S-K-H-A-T-F-A-N-E-D-A-A-L-E-A-L-K-A-K-S-D-N-L-Y-K-N-A-V-E-L-R-N-F-V-K-A-K-I-D-S-L-K-P-D-A-K-T-F-V-D-E-I-I-A-K-A-R-S-L-R-S-D-D-G-H-K-L-D-T-E-K-I-K-Q-A-A-R-D-I-I-A-K-Y-Q-A-L-S-E-E-T-K-E-E-L-K-V-T-F-P-A-I-A-K-I-I-G-N-E-K-L-K-R-N-A-S-T-F-L-Q-K-N"} +{"text": "### FUNCTION Binds retinol and different fatty acids ### SEQUENCE -M-Y-H-R-L-I-L-L-A-L-V-G-T-T-M-A-N-V-I-P-F-S-M-N-N-I-P-E-E-Y-K-E-F-I-P-E-E-V-R-N-F-Y-K-D-L-T-V-E-D-K-E-I-L-R-E-L-A-S-K-H-A-T-F-A-N-E-D-A-A-L-E-A-L-K-D-K-S-D-K-L-Y-K-N-A-V-E-L-R-N-F-V-K-A-K-I-D-S-L-K-P-D-A-K-I-F-V-D-E-I-I-A-K-A-R-S-L-R-S-D-D-G-H-K-L-D-T-E-K-I-K-Q-A-A-R-D-I-I-A-K-Y-Q-A-L-S-E-E-T-K-E-E-L-K-V-T-F-P-A-I-A-K-I-I-G-N-E-K-L-K-R-N-A-S-T-F-L-Q-K-N"} +{"text": "### FUNCTION May operate as a co-chaperone of the male germ cell- and haploid stage-specific Hsp70 proteins ### SEQUENCE -M-V-D-Y-Y-E-V-L-D-V-P-R-Q-A-S-S-E-A-I-K-K-A-Y-R-K-L-A-L-K-W-H-P-D-K-N-P-E-N-K-E-E-A-E-R-R-F-K-Q-V-A-E-A-Y-E-V-L-S-D-A-K-K-R-D-I-Y-D-R-Y-G-E-A-G-A-E-G-G-C-T-G-G-R-P-F-E-D-P-F-E-Y-V-F-S-F-R-D-P-A-D-V-F-R-E-F-F-G-G-Q-D-P-F-S-F-D-L-L-G-N-P-L-E-N-I-L-G-G-S-E-E-L-L-G-K-Q-K-Q-S-V-C-T-P-F-L-C-L-Q"} +{"text": "### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane ### SEQUENCE -M-N-S-S-Y-F-P-G-V-L-G-V-R-W-V-H-T-N-R-K-L-Q-K-R-K-E-E-H-G-A-F-Q-D-S-L-H-F-M-I-P-A-A-E-T-K-D-L-G-A-S-V-T-V-G-N-S-L-T-R-A-F-R-Q-V-D-R-I-C-Q-R-N-N-V-P-R-L-F-R-S-Q-R-F-Y-E-K-P-S-E-K-R-S-R-V-R-S-E-R-H-R-A-R-F-R-A-G-I-V-R-L-V-N-L-A-K-N-M-R-R-W-G-Y"} +{"text": "### FUNCTION Required for the assembly of the TOM receptor complex, which is responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins ### SEQUENCE -M-S-A-E-E-I-S-N-P-L-A-E-S-G-V-T-I-S-S-D-S-E-Q-Y-S-A-P-E-S-A-S-P-Q-S-P-S-S-S-S-P-A-V-V-L-Y-Q-P-P-T-V-W-S-L-F-R-S-A-V-I-N-L-F-L-P-F-V-N-G-M-M-L-G-F-G-E-L-F-A-H-E-A-A-F-R-L-G-W-S-N-T-K-V-F-P-V-S-R-R-D-A-R-P-I-G-P-G-V-E-V-V-E-R-P-R-R-R-V-D-L-D-D-H-L-D-E-L-T-S-L-E"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-R-T-L-Y-L-V-L-L-S-L-L-T-L-A-S-P-I-A-A-Q-F-G-S-F-F-D-Q-M-F-G-G-H-G-H-Q-Q-T-Q-Q-Q-Q-Q-H-Q-G-H-G-H-Q-Q-H-P-N-V-P-S-D-P-S-I-Y-Q-A-N-Y-Q-R-A-H-C-D-K-Y-L-C-P-D-T-L-A-C-V-H-Y-P-H-H-C-P-C-P-W-P-L-H-E-D-K-A-E-L-A-E-G-Q-R-I-C-V-S-K-G-G-F-K-A-G-E-A-A-R-K-I-E-L-A-R-K-G-M-L"} +{"text": "### FUNCTION Component of the general transcription and DNA repair factor IIH of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription ### SEQUENCE -M-P-R-A-I-R-G-V-L-I-Q-C-E-P-A-I-K-S-I-I-V-H-L-D-S-V-N-N-D-I-I-I-E-D-L-D-E-Q-T-L-V-V-K-E-N-M-V-Q-L-L-K-Q-K-L-E-D-R-L-K-E-T-Y-R-P-E-E-P-L-A-D-S-D"} +{"text": "### FUNCTION Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca complex are a number of protein kinases and phosphatases ### SEQUENCE -M-A-D-Q-L-S-E-E-Q-I-S-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-T-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-G-E-L-Q-D-M-I-N-E-V-D-A-D-G-N-G-T-I-D-F-P-E-F-L-T-M-M-A-R-K-M-R-D-T-D-S-E-E-E-I-K-E-A-F-K-V-F-D-K-D-G-N-G-Y-I-S-A-A-E-L-R-H-V-M-T-N-L-G-E-K-L-T-D-T-E-V-D-E-M-I-R-E-A-D-V-D-G-D-G-Q-I-N-Y-D-E-F-V-K-M-M-L-S-K"} +{"text": "### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-A-T-D-V-A-F-D-T-S-M-G-S-F-T-V-E-L-Y-N-A-H-A-P-K-T-C-K-N-F-A-T-L-A-Q-R-G-Y-Y-N-N-V-I-F-H-R-I-I-P-N-F-M-V-Q-T-G-D-P-T-G-T-G-R-G-G-S-S-I-Y-G-E-K-F-E-D-E-I-N-P-N-L-K-H-T-G-A-G-I-L-S-M-A-N-S-G-P-N-N-N-G-S-Q-F-F-I-T-L-A-P-Q-P-W-L-D-G-K-H-T-I-F-G-R-V-K-S-G-M-R-V-I-Q-R-M-G-L-V-K-T-N-S-E-D-R-P-V-D-G-V-K-I-L-R-A-R-I-V-E-E-T-G-D-E"} +{"text": "### FUNCTION Toxic component of a type I toxin-antitoxin ### SEQUENCE -M-D-S-L-T-Q-K-L-T-V-L-I-A-V-L-E-L-L-V-A-L-L-R-L-I-D-L-L-K"} +{"text": "### FUNCTION Involved in the degradation and recycling of damaged RNA It is itself a target for degradation by the ATP-dependent protease Lon ### SEQUENCE -M-T-D-T-H-S-I-A-Q-P-F-E-A-E-V-S-P-A-N-N-R-Q-L-T-V-S-Y-A-S-R-Y-P-D-Y-S-R-I-P-A-I-T-L-K-G-Q-W-L-E-A-A-G-F-A-T-G-T-V-V-D-V-K-V-M-E-G-C-I-V-L-T-A-Q-P-P-A-A-A-E-S-E-L-M-Q-S-L-R-Q-V-C-K-L-S-A-R-K-Q-R-Q-V-Q-E-F-I-G-V-I-A-G-K-Q-K-V-A"} +{"text": "### FUNCTION Makes mgtA transcription sensitive to intracellular proline levels Under low levels of proline this protein cannot be fully translated, and a stem loop forms which permits transcription of the downstream mgtA gene ### SEQUENCE -M-E-P-D-P-T-P-L-P-R-R-R-L-K-L-F-R"} +{"text": "### FUNCTION Repressor of the frmRAB operon ### SEQUENCE -M-P-S-T-P-E-E-K-K-K-V-L-T-R-V-R-R-I-R-G-Q-I-D-A-L-E-R-S-L-E-G-D-A-E-C-R-A-I-L-Q-Q-I-A-A-V-R-G-A-A-N-G-L-M-A-E-V-L-E-S-H-I-R-E-T-F-D-R-N-D-C-Y-S-R-E-V-S-Q-S-V-D-D-T-I-E-L-V-R-A-Y-L-K"} +{"text": "### FUNCTION Part of the lpfABCC'DE fimbrial operon LP fimbriae may participate in the interaction with eukaryotic cells by assisting in microcolony formation ### SEQUENCE -M-E-F-F-M-K-K-V-V-F-A-L-T-A-L-A-L-T-S-G-T-V-F-A-A-E-S-G-D-G-T-V-K-F-T-G-E-I-V-D-S-P-C-V-L-S-V-D-S-Q-N-Q-E-V-V-L-G-Q-V-Q-K-S-V-F-A-A-V-G-D-K-S-P-A-K-P-F-E-I-K-L-E-D-C-D-T-T-T-M-K-K-A-N-V-S-F-S-G-V-G-D-A-D-K-S-D-L-I-S-V-S-T-E-A-G-A-A-K-G-V-G-I-G-I-Y-D-N-S-N-T-L-V-A-L-N-G-G-K-A-S-V-D-L-S-K-G-Q-T-V-L-Y-F-T-A-N-Y-V-S-T-L-A-T-V-T-T-G-Y-G-N-A-Q-V-D-F-N-L-S-Y-E"} +{"text": "### FUNCTION Part of the lpfABCC'DE fimbrial operon LP fimbriae may participate in the interaction with eukaryotic cells by assisting in microcolony formation ### SEQUENCE -M-K-F-K-R-L-L-H-S-G-I-A-S-L-S-L-V-A-C-G-V-N-A-A-T-D-L-G-P-A-G-D-I-H-F-S-I-T-I-T-T-K-A-C-E-M-E-K-S-D-L-E-V-D-M-G-T-M-T-L-Q-K-P-A-A-V-G-T-V-L-S-K-K-D-F-T-I-E-L-K-E-C-D-G-I-S-K-A-T-V-E-M-D-S-Q-S-D-S-D-D-D-S-M-F-A-L-E-A-G-G-A-T-G-V-A-L-K-I-E-D-D-K-G-T-Q-Q-V-P-K-G-S-S-G-T-P-I-E-W-A-I-D-G-E-T-T-S-L-H-Y-Q-A-S-Y-V-V-V-N-T-Q-A-T-G-G-T-A-N-A-L-V-N-F-S-I-T-Y-E"} +{"text": "### FUNCTION May act as a transcriptional regulator of dctA Could be involved in the regulation of the genes coding for the type III secretion system in enterohaemorragic strains ### SEQUENCE -M-F-L-I-I-T-R-D-T-M-F-F-T-A-M-K-N-I-L-S-K-G-N-V-V-H-I-Q-N-E-E-E-I-D-V-M-L-H-Q-N-A-F-V-I-I-D-T-L-M-N-N-V-F-H-S-N-F-L-T-Q-I-E-R-L-K-P-V-H-V-I-I-F-S-P-F-N-I-K-R-C-L-G-K-V-P-V-T-F-V-P-R-T-I-T-I-I-D-F-V-A-L-I-N-G-S-Y-C-S-V-P-E-A-N-V-S-L-S-R-K-Q-H-Q-V-L-S-C-I-A-N-Q-M-T-T-E-D-I-L-E-K-L-K-I-S-L-K-T-F-Y-C-H-K-H-N-I-M-M-I-L-N-L-K-R-I-N-E-L-V-R-H-Q-H-I-D-Y-L-V"} +{"text": "### FUNCTION Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate ### SEQUENCE -M-M-G-K-L-I-W-L-M-G-P-S-G-S-G-K-D-S-L-L-A-E-L-R-L-R-E-Q-T-Q-L-L-V-A-H-R-Y-I-T-R-D-A-S-A-G-S-E-N-H-I-A-L-S-E-Q-E-F-F-T-R-A-G-Q-N-L-L-A-L-S-W-H-A-N-G-L-Y-Y-G-V-G-V-E-I-D-L-W-L-H-A-G-F-D-V-L-V-N-G-S-R-A-H-L-P-Q-A-R-A-R-Y-Q-S-A-L-L-P-I-C-L-Q-V-S-P-E-I-L-R-Q-R-L-E-N-R-G-R-E-N-A-S-E-I-N-A-R-L-A-R-A-A-R-Y-T-P-Q-D-C-H-T-L-N-N-D-G-S-L-R-Q-S-V-D-T-L-L-T-L-I-H-Q-K-E-K-H-H-A-C-L"} +{"text": "### FUNCTION Required for formate-dependent nitrite reduction Not required for the biosynthesis of any of the c-type cytochromes nor for the secretion of the periplasmic cytochromes ### SEQUENCE -M-K-Q-P-Q-I-P-V-K-M-L-T-T-L-T-I-L-M-V-F-L-C-I-G-S-Y-L-L-S-P-K-W-Q-A-V-R-A-E-Y-Q-R-Q-R-D-P-L-H-Q-F-A-S-Q-Q-N-P-E-A-Q-L-Q-A-L-Q-D-K-I-R-A-N-P-Q-N-S-E-Q-W-A-L-L-G-E-Y-Y-L-W-Q-N-D-Y-S-N-S-L-L-A-Y-R-Q-A-L-Q-L-R-G-E-N-A-E-L-Y-A-A-L-A-T-V-L-Y-Y-Q-A-S-Q-H-M-T-A-Q-T-R-A-M-I-D-K-A-L-A-L-D-S-N-E-I-T-A-L-M-L-L-A-S-D-A-F-M-Q-A-N-Y-A-Q-A-I-E-L-W-Q-K-V-M-D-L-N-S-P-R-I-N-R-T-Q-L-V-E-S-I-N-M-A-K-L-L-Q-R-R-S-D"} +{"text": "### FUNCTION Not required for the biosynthesis of any of the c-type cytochromes Possible subunit of a heme lyase ### SEQUENCE -M-Y-K-G-L-L-T-L-L-L-L-F-T-C-F-A-R-A-Q-V-V-D-T-W-Q-F-A-N-P-Q-Q-Q-Q-Q-A-L-N-I-A-S-Q-L-R-C-P-Q-C-Q-N-Q-N-L-L-E-S-N-A-P-V-A-V-S-M-R-H-Q-V-Y-S-M-V-A-E-G-K-S-E-V-E-I-I-G-W-M-T-E-R-Y-G-D-F-V-R-Y-N-P-P-L-T-G-Q-T-L-V-L-W-A-L-P-V-V-L-L-L-L-M-A-L-I-L-W-R-V-R-A-K-R"} +{"text": "### FUNCTION May be involved in an alternative pathway for phosphopantetheinyl transfer and holo-ACP synthesis in Ecoli The native apo-protein substrate is unknown Is able to functionally replace AcpS in vivo but only when expressed at high levels ### SEQUENCE -M-Y-R-I-V-L-G-K-V-S-T-L-S-A-A-P-L-P-P-G-L-R-E-Q-A-P-Q-G-P-R-R-E-R-W-L-A-G-R-A-L-L-S-H-T-L-S-P-L-P-E-I-I-Y-G-E-Q-G-K-P-A-F-A-P-E-T-P-L-W-F-N-L-S-H-S-G-D-D-I-A-L-L-L-S-D-E-G-E-V-G-C-D-I-E-V-I-R-P-R-A-N-W-R-W-L-A-N-A-V-F-S-L-G-E-H-A-E-M-D-A-V-H-P-D-Q-Q-L-E-M-F-W-R-I-W-T-R-K-E-A-I-V-K-Q-R-G-G-S-A-W-Q-I-V-S-V-D-S-T-Y-H-S-S-L-S-V-S-H-C-Q-L-E-N-L-S-L-A-I-C-T-P-T-P-F-T-L-T-A-D-S-V-Q-W-I-D-S-V-N"} +{"text": "### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-L-G-M-Q-S-I-R-R-R-Q-L-I-D-A-T-L-E-A-I-N-E-V-G-M-H-D-A-T-I-A-Q-I-A-R-R-A-G-V-S-T-G-I-I-S-H-Y-F-R-D-K-N-G-L-L-E-A-T-M-R-D-I-T-S-Q-L-R-D-A-V-L-N-R-L-H-A-L-P-Q-G-S-A-E-Q-R-L-Q-A-I-V-G-G-N-F-D-E-T-Q-V-S-S-A-A-M-K-A-W-L-A-F-W-A-S-S-M-H-Q-P-M-L-Y-R-L-Q-Q-V-S-S-R-R-L-L-S-N-L-V-S-E-F-R-R-E-L-P-R-H-Q-A-Q-E-A-G-Y-G-L-A-A-L-I-D-G-L-W-L-R-A-A-L-S-G-K-P-L-D-K-P-L-A-H-S-L-T-R-H-F-I-T-Q-H-L-P-T-D"} +{"text": "### FUNCTION Iron-sulfur subunit of the xanthine dehydrogenase complex ### SEQUENCE -M-N-H-S-E-T-I-T-I-E-C-T-I-N-G-M-P-F-Q-L-H-A-V-P-G-T-P-L-S-E-L-L-R-E-Q-G-L-L-S-V-K-Q-G-C-C-V-G-E-C-G-A-C-T-V-L-V-D-G-T-A-I-D-S-C-L-Y-L-A-A-W-A-E-G-K-E-I-R-T-L-E-G-E-A-K-G-G-K-L-S-H-V-Q-Q-A-Y-A-K-S-G-A-V-Q-C-G-F-C-T-P-G-L-I-M-A-T-T-A-M-L-A-K-P-R-E-K-P-L-T-I-T-E-I-R-R-G-L-A-G-N-L-C-R-C-T-G-Y-Q-M-I-V-N-T-V-L-D-C-E-K-T-K"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-D-Q-F-E-C-I-N-V-A-D-A-H-Q-K-L-Q-E-K-E-A-V-L-V-D-I-R-D-P-Q-S-F-A-M-G-H-A-V-Q-A-F-H-L-T-N-D-T-L-G-A-F-M-R-N-N-D-F-D-T-P-V-M-V-M-C-Y-H-G-N-S-S-K-G-A-A-Q-Y-L-L-Q-Q-G-Y-D-V-V-Y-S-I-D-G-G-F-E-A-W-Q-R-Q-F-P-A-E-V-A-Y-G-A"} +{"text": "### FUNCTION Required for growth and/or survival at acidic conditions ### SEQUENCE -M-K-K-V-L-A-L-V-V-A-A-A-M-G-L-S-S-A-A-F-A-A-E-T-A-T-T-P-A-P-T-A-T-T-T-K-A-A-P-A-K-T-T-H-H-K-K-Q-H-K-A-A-P-A-Q-K-A-Q-A-A-K-K-H-H-K-N-T-K-A-E-Q-K-A-P-E-Q-K-A-Q-A-A-K-K-H-A-K-K-H-S-H-Q-Q-P-A-K-P-A-A-Q-P-A-A"} +{"text": "### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-T-L-P-S-G-H-P-K-S-R-L-I-K-K-F-T-V-L-G-P-Y-I-R-E-G-K-C-E-D-N-R-F-F-F-D-C-L-A-V-C-V-N-V-K-P-A-P-E-V-R-E-F-W-G-W-W-M-E-L-E-A-Q-E-S-R-F-T-Y-S-Y-Q-F-G-L-F-D-K-A-G-D-W-K-S-V-P-V-K-D-T-E-V-V-E-R-L-E-H-T-L-R-E-F-H-E-K-L-R-E-L-L-T-T-L-N-L-K-L-E-P-A-D-D-F-R-D-E-P-V-K-L-T-A"} +{"text": "### FUNCTION In the presence of manganese, represses expression of mntH and mntS Up-regulates expression of mntP ### SEQUENCE -M-S-R-R-A-G-T-P-T-A-K-K-V-T-Q-L-V-N-E-E-E-H-V-E-G-F-R-Q-V-R-E-A-H-R-R-E-L-I-D-D-Y-V-E-L-I-S-D-L-I-R-E-V-G-E-A-R-Q-V-D-M-A-A-R-L-G-V-S-Q-P-T-V-A-K-M-L-K-R-L-A-T-M-G-L-I-E-M-I-P-W-R-G-V-F-L-T-A-E-G-E-K-L-A-Q-E-S-R-E-R-H-Q-I-V-E-N-F-L-L-V-L-G-V-S-P-E-I-A-R-R-D-A-E-G-M-E-H-H-V-S-E-E-T-L-D-A-F-R-L-F-T-Q-K-H-G-A-K"} +{"text": "### FUNCTION Toxic component of a type I toxin-antitoxin When overexpressed kills cells within minutes ### SEQUENCE -M-L-T-K-Y-A-L-V-A-I-I-V-L-C-C-T-V-L-G-F-T-L-M-V-G-D-S-L-C-E-L-S-I-R-E-R-G-M-E-F-K-A-V-L-A-Y-E-S-K-K"} +{"text": "### FUNCTION Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under anaerobic conditions, however the precise biochemical function in metabolism of phenolic acid is unknown ### SEQUENCE -M-I-C-P-R-C-A-D-E-Q-I-E-V-M-A-K-S-P-V-K-D-V-W-T-V-Y-Q-C-Q-H-C-L-Y-T-W-R-D-T-E-P-L-R-R-T-S-R-E-H-Y-P-E-A-F-R-M-T-Q-K-D-I-D-D-A-P-M-V-P-S-I-P-P-L-L-A-E-G-K-R"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-R-F-A-I-V-V-T-G-P-A-Y-G-T-Q-Q-A-S-S-A-F-Q-F-A-Q-A-L-I-A-E-G-H-K-L-S-S-V-F-F-Y-R-E-G-V-Y-N-A-N-H-L-T-S-P-A-S-D-E-F-D-L-V-R-G-W-Q-Q-L-N-A-Q-H-G-V-A-L-N-I-C-V-A-A-A-L-R-R-G-V-V-D-E-M-E-A-G-R-L-G-L-A-S-S-N-L-Q-Q-G-F-T-L-S-G-L-G-A-L-A-E-A-S-L-T-C-D-R-V-V-Q-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-K-R-I-A-F-V-F-S-T-V-P-H-G-T-A-A-G-R-E-G-L-D-A-L-L-A-T-S-A-L-T-D-E-L-A-V-F-F-I-A-D-G-V-F-Q-L-L-P-G-Q-K-P-D-A-V-L-A-R-D-Y-I-A-T-F-K-L-L-D-L-Y-D-I-E-Q-C-W-V-C-A-A-S-L-R-E-R-G-L-D-P-Q-T-P-F-V-V-E-A-T-P-L-E-A-D-A-L-R-R-E-L-A-N-Y-D-V-I-L-R-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-L-H-T-L-H-R-S-P-W-L-T-D-F-A-A-L-L-R-L-L-S-E-G-D-E-L-L-L-L-Q-D-G-V-T-A-A-V-D-G-N-R-Y-L-E-S-L-R-N-A-P-I-K-V-Y-A-L-N-E-D-L-I-A-R-G-L-T-G-Q-I-S-N-D-I-I-P-I-D-Y-T-D-F-V-R-L-T-V-K-H-S-G-Q-M-A-W"} +{"text": "### FUNCTION A GTPase-activating protein that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-K-P-S-S-P-S-R-S-K-G-H-A-K-A-R-R-K-T-R-E-E-L-N-Q-E-A-R-D-R-K-R-Q-K-K-R-R-G-H-A-P-G-S-R-A-A-G-G-N-N-T-S-G-S-K-G-Q-N-A-P-K-D-P-R-I-G-S-K-T-P-I-P-L-G-V-T-E-K-V-T-K-Q-H-K-P-K-S-E-K-P-M-L-S-P-Q-A-E-L-E-L-L-E-T-D-E-R-L-D-A-L-L-E-R-L-E-A-G-E-T-L-S-A-E-E-Q-S-W-V-D-A-K-L-D-R-I-D-E-L-M-Q-K-L-G-L-S-Y-D-D-D-E-E-E-E-E-D-E-K-Q-E-D-M-M-R-L-L-R-G-N"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-R-G-L-R-P-A-L-S-T-F-I-F-L-L-L-I-T-G-G-V-Y-P-L-L-T-T-A-L-G-Q-W-W-F-P-W-Q-A-N-G-S-L-I-R-E-G-D-T-V-R-G-S-A-L-I-G-Q-N-F-T-D-N-G-Y-F-H-G-R-P-S-A-T-A-E-M-P-Y-N-P-Q-A-S-G-G-S-N-L-A-V-S-N-P-E-L-D-K-L-I-A-A-R-V-A-A-L-R-A-A-N-P-N-A-S-T-S-V-P-V-E-L-V-T-A-S-A-S-G-L-D-N-N-I-T-P-Q-A-A-A-W-Q-I-P-R-V-A-K-A-R-N-L-S-V-E-Q-L-T-Q-L-I-A-K-Y-S-Q-Q-P-L-V-K-Y-I-G-Q-P-V-V-N-I-V-E-L-N-L-A-L-D-K-L-D-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-S-T-E-A-T-A-K-I-V-S-E-F-G-R-D-A-N-D-T-G-S-T-E-V-Q-V-A-L-L-T-A-Q-I-N-H-L-Q-G-H-F-A-E-H-K-K-D-H-H-S-R-R-G-L-L-R-M-V-S-Q-R-R-K-L-L-D-Y-L-K-R-K-D-V-A-R-Y-T-R-L-I-E-R-L-G-L-R-R"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-L-Y-L-T-R-R-V-E-T-P-A-Q-T-T-A-S-V-T-L-P-V-D-M-R-V-K-S-R-I-K-V-T-L-N-D-G-R-Q-A-G-L-L-L-P-R-G-L-L-L-R-D-G-D-I-L-S-N-E-N-G-D-E-F-I-K-V-I-A-A-D-E-A-V-S-V-V-R-C-A-D-P-F-M-L-A-K-A-C-W-H-L-G-N-R-H-V-P-L-Q-I-M-P-G-E-L-R-Y-H-H-D-H-V-L-D-D-M-L-R-Q-F-G-L-D-V-D-F-A-H-L-P-F-E-P-E-A-G-A-Y-A-S-K-S-H-A-H-N-H-D-Q-E-H-S-H"} +{"text": "### FUNCTION Exporter of O-acetylserine and cysteine ### SEQUENCE -M-T-P-T-L-L-S-A-F-W-T-Y-T-L-I-T-A-M-T-P-G-P-N-N-I-L-A-L-S-S-A-T-T-H-G-F-H-Q-S-T-R-V-L-A-G-M-S-L-G-F-L-I-V-M-L-L-C-A-G-I-S-F-S-L-A-V-I-D-P-A-A-V-H-L-L-S-W-A-G-A-A-Y-I-V-W-L-A-W-K-I-A-T-S-P-T-K-E-D-G-L-Q-T-K-P-I-S-F-W-A-S-F-A-L-Q-F-V-N-V-K-I-I-L-Y-G-V-T-A-L-S-T-F-V-L-P-Q-T-Q-A-L-S-W-I-V-G-V-S-V-L-L-A-M-I-G-T-F-G-N-V-C-W-A-L-A-G-H-L-F-Q-R-L-F-R-Q-Y-G-R-Q-L-N-I-V-L-A-L-L-L-I-Y-C-A-V-R-I-F-Y"} +{"text": "### FUNCTION Overproduction of CaiE stimulates the activity of CaiB and CaiD ### SEQUENCE -M-S-Y-Y-A-F-E-G-L-I-P-V-V-H-P-T-A-F-V-H-P-S-A-V-L-I-G-D-V-I-V-G-A-G-V-Y-I-G-P-L-A-S-L-R-G-D-Y-G-R-L-I-V-Q-A-G-A-N-I-Q-D-G-C-I-M-H-G-Y-T-D-T-D-T-I-V-G-E-N-G-H-I-G-H-G-A-I-L-H-G-C-V-I-G-R-D-A-L-V-G-M-N-S-V-I-M-D-G-A-V-I-G-E-E-S-I-V-A-A-M-S-F-V-K-A-G-F-H-G-E-K-R-Q-L-L-M-G-T-P-A-R-A-V-R-S-V-S-D-D-E-L-H-W-K-R-L-N-T-K-E-Y-Q-D-L-V-G-R-C-H-A-S-L-H-E-T-Q-P-L-R-Q-M-E-E-N-R-P-R-L-Q-G-T-T-D-V-T-P-K-R"} +{"text": "### FUNCTION Part of the multicomponent 3-phenylpropionate dioxygenase Converts 3-phenylpropionic acid , respectively ### SEQUENCE -M-S-A-Q-V-S-L-E-L-H-H-R-I-S-Q-F-L-F-H-E-A-S-L-L-D-D-W-K-F-R-D-W-L-A-Q-L-D-E-E-I-C-Y-T-M-R-T-T-V-N-A-Q-T-R-D-R-R-K-G-V-Q-P-P-T-T-W-I-F-N-D-T-K-D-Q-L-E-R-R-I-A-R-L-E-T-G-M-A-W-A-E-E-P-P-S-R-T-R-H-L-I-S-N-C-Q-I-S-E-T-D-I-P-N-V-F-A-V-R-V-N-Y-L-L-Y-R-A-Q-K-E-R-D-E-T-F-Y-V-G-T-R-F-D-K-V-R-R-L-E-D-D-N-W-R-L-L-E-R-D-I-V-L-D-Q-A-V-I-T-S-H-N-L-S-V-L-F"} +{"text": "### FUNCTION This protein is involved in control of the biosynthesis of threonine ### SEQUENCE -M-K-R-I-S-T-T-I-T-T-T-I-T-T-T-I-T-I-T-I-T-T-G-N-G-A-G"} +{"text": "### FUNCTION Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base The complementary strand guanine functions in substrate recognition Required for DNA damage lesion repair in stationary-phase cells ### SEQUENCE -M-V-E-D-I-L-A-P-G-L-R-V-V-F-C-G-I-N-P-G-L-S-S-A-G-T-G-F-P-F-A-H-P-A-N-R-F-W-K-V-I-Y-Q-A-G-F-T-D-H-Q-L-K-P-Q-E-A-Q-H-L-L-D-Y-R-C-G-V-T-K-L-V-D-R-P-T-V-Q-A-N-E-I-S-K-Q-E-L-H-A-G-G-R-K-L-I-E-K-I-E-D-Y-Q-P-Q-A-L-A-I-L-G-K-Q-A-Y-E-Q-G-F-S-Q-R-G-A-Q-W-G-K-Q-T-L-S-I-G-S-T-Q-I-W-V-L-P-N-P-S-G-L-S-R-V-S-L-E-K-L-V-E-A-Y-R-E-L-D-Q-A-L-V-V-R-G-R"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-D-S-E-F-H-R-L-A-D-Q-L-W-L-T-I-E-E-R-L-D-D-W-D-G-D-S-D-I-D-C-E-I-N-G-G-V-L-T-I-T-F-E-N-G-S-K-I-I-I-N-R-Q-E-P-L-H-Q-V-W-L-A-T-K-Q-G-G-Y-H-F-D-L-K-G-D-E-W-I-C-D-R-S-G-E-T-F-R-D-L-L-E-Q-A-A-T-Q-Q-A-G-E-T-V-S-F-R"} +{"text": "### FUNCTION Involved in pyrimidine catabolism Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions ### SEQUENCE -M-P-K-S-V-I-I-P-A-G-S-S-A-P-L-A-P-F-V-P-G-T-L-A-D-G-V-V-Y-V-S-G-T-L-A-F-D-Q-H-N-N-V-L-F-A-D-D-P-K-A-Q-T-R-H-V-L-E-T-I-R-K-V-I-E-T-A-G-G-T-M-A-D-V-T-F-N-S-I-F-I-T-D-W-K-N-Y-A-A-I-N-E-T-Y-A-E-F-F-P-G-D-K-P-A-R-F-C-I-Q-C-G-L-V-K-P-D-A-L-V-E-I-A-T-I-A-H-I-A-K"} +{"text": "### FUNCTION May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted ### SEQUENCE -M-N-E-A-V-S-P-G-A-L-S-T-L-F-T-D-A-R-T-H-N-G-W-R-E-T-P-V-S-D-E-T-L-R-E-L-Y-A-L-M-K-W-G-P-T-S-A-N-C-S-P-A-R-I-V-F-I-R-T-A-E-G-K-E-R-L-R-P-A-L-S-S-G-N-L-Q-K-T-L-T-A-P-V-T-A-I-V-A-W-D-S-E-F-Y-E-R-L-P-Q-L-F-P-H-G-D-A-R-S-W-F-T-S-S-P-Q-L-A-E-E-T-A-F-R-N-S-S-M-Q-A-A-Y-L-I-I-A-C-R-A-L-G-L-D-T-G-P-M-S-G-F-D-R-Q-H-V-D-D-A-F-F-A-G-S-T-L-K-S-N-L-L-I-N-I-G-Y-G-D-S-S-K-L-F-A-R-L-P-R-L-S-F-E-E-A-C-G-L-L"} +{"text": "### FUNCTION Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions ### SEQUENCE -M-H-A-T-T-V-K-N-K-I-T-Q-R-D-N-Y-K-E-I-M-S-V-I-V-V-I-L-L-L-T-L-T-L-I-A-I-F-S-A-I-D-Q-L-G-I-S-E-M-G-R-I-A-R-D-L-T-H-F-I-V-N-S-L-Q-D"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-V-K-L-A-F-P-R-E-L-R-L-L-T-P-S-Q-F-T-F-V-F-Q-Q-P-Q-R-A-G-T-P-Q-I-T-I-L-G-R-L-N-S-L-G-H-P-R-I-G-L-T-V-A-K-K-N-V-R-R-A-H-E-R-N-R-I-K-R-L-T-R-E-S-F-R-L-R-Q-H-E-L-P-A-M-D-F-V-V-V-A-K-K-G-V-A-N-L-D-N-R-A-L-S-E-A-L-E-K-L-W-R-R-H-C-R-L-A-R-G-S"} +{"text": "### FUNCTION This protein is required for primosome-dependent normal DNA replication ### SEQUENCE -M-S-S-R-V-L-T-P-D-V-V-G-I-D-A-L-V-H-D-H-Q-T-V-L-A-K-A-E-G-G-V-V-A-V-F-A-N-N-A-P-A-F-Y-A-V-T-P-A-R-L-A-E-L-L-A-L-E-E-K-L-A-R-P-G-S-D-V-D-L-D-D-Q-L-Y-Q-E-P-Q-A-A-P-V-A-V-P-M-G-K-F-A-M-Y-P-D-W-Q-P-D-A-D-F-I-R-L-A-A-L-W-G-V-A-L-R-E-P-V-T-T-E-E-L-A-S-F-I-A-Y-W-Q-A-E-G-K-V-F-H-H-V-Q-W-Q-Q-K-L-A-R-S-L-Q-I-G-R-A-S-N-G-G-L-P-K-R-D-V-N-T-V-S-E-P-D-S-Q-I-P-P-G-F-R-G"} +{"text": "### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway ### SEQUENCE -M-M-R-Q-S-L-Q-A-V-L-P-E-I-S-G-N-K-T-S-L-L-R-K-S-V-C-S-D-L-L-T-L-F-N-S-P-H-S-T-L-P-S-L-L-V-S-G-M-P-E-W-Q-V-H-N-P-S-D-K-H-L-Q-S-W-Y-C-R-Q-L-R-S-A-L-L-F-H-E-P-R-I-A-A-L-Q-V-N-L-K-E-A-Y-C-H-T-L-A-I-S-L-E-I-M-L-Y-H-D-D-E-P-L-T-F-D-L-V-W-D-N-G-G-W-R-S-A-T-L-E-N-V-S"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-Q-V-I-L-D-L-Q-L-A-C-E-D-N-S-G-L-P-E-E-S-Q-F-Q-T-W-L-N-A-V-I-P-Q-F-Q-E-E-S-E-V-T-I-R-V-V-D-T-A-E-S-H-S-L-N-L-T-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-V-P-P-G-M-E-M-S-L-L-G-D-L-V-I-C-R-Q-M-V-E-K-E-A-Q-E-Q-G-K-P-L-E-A-H-W-A-H-M-V-V-H-G-S-L-H-L-L-G-Y-D-H-I-E-D-D-E-A-E-E-M-E-A-L-E-T-E-I-M-L-A-L-G-Y-E-D-P-Y-I-A-E-K-E"} +{"text": "### FUNCTION Together with LptD, is involved in the assembly of lipopolysaccharide at the surface of the outer membrane Required for the proper assembly of LptD Binds LPS and may serve as the LPS recognition site at the outer membrane ### SEQUENCE -M-R-Y-L-A-T-L-L-L-S-L-A-V-L-I-T-A-G-C-G-W-H-L-R-D-T-T-Q-V-P-S-T-M-K-V-M-I-L-D-S-G-D-P-N-G-P-L-S-R-A-V-R-N-Q-L-R-L-N-G-V-E-L-L-D-K-E-T-T-R-K-D-V-P-S-L-R-L-G-A-V-S-I-S-Q-D-T-A-S-V-F-R-N-G-Q-T-A-E-Y-Q-M-V-M-T-V-S-A-S-V-L-I-P-G-R-D-I-Y-P-I-S-T-K-V-F-R-S-F-F-D-N-P-Q-M-A-L-A-K-D-N-E-Q-E-M-I-I-K-E-M-Y-D-R-A-A-E-Q-L-I-R-K-L-P-S-I-R-A-A-D-I-R-S-D-E-E-Q-T-S-T-T-T-D-T-P-A-T-P-A-R-V-S-T-T-L-G-N"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-L-C-Q-S-A-V-E-I-I-Q-R-Q-A-E-Q-H-D-V-K-R-V-T-A-V-W-L-E-I-G-A-L-S-C-V-E-E-S-A-V-R-F-S-F-E-I-V-C-H-G-T-V-A-Q-G-C-D-L-H-I-V-Y-K-P-A-Q-A-W-C-W-D-C-S-Q-V-V-E-V-H-Q-H-D-A-Q-C-P-L-C-H-G-E-R-L-R-V-D-T-G-D-S-L-I-V-K-S-I-E-V-E"} +{"text": "### FUNCTION Toxic component of a type I toxin-antitoxin When overexpressed kills cells within minutes ### SEQUENCE -M-L-T-K-Y-A-L-V-A-V-I-V-L-C-L-T-V-L-G-F-T-L-L-V-G-D-S-L-C-E-F-T-V-K-E-R-N-I-E-F-K-A-V-L-A-Y-E-P-K-K"} +{"text": "### FUNCTION Toxic component of a type I toxin-antitoxin When overexpressed kills cells within minutes ### SEQUENCE -M-L-T-K-Y-A-L-V-A-V-I-V-L-C-L-T-V-P-G-F-T-L-L-V-G-D-S-L-C-E-F-T-V-K-E-R-N-I-E-F-R-A-V-L-A-Y-E-P-K-K"} +{"text": "### FUNCTION Part of a cation efflux system that mediates resistance to copper and silver Binds one copper per polypeptide ### SEQUENCE -M-K-K-A-L-Q-V-A-M-F-S-L-F-T-V-I-G-F-N-A-Q-A-N-E-H-H-H-E-T-M-S-E-A-Q-P-Q-V-I-S-A-T-G-V-V-K-G-F-D-L-E-S-K-K-I-T-I-H-H-D-P-I-A-A-V-N-W-P-E-M-T-M-R-F-T-I-T-P-Q-T-K-M-S-G-I-K-T-G-D-K-V-A-F-N-F-V-Q-Q-G-N-L-S-L-L-Q-D-I-K-V-S-Q"} +{"text": "### FUNCTION Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE Its activity is ATP-independent ### SEQUENCE -M-R-N-F-D-L-S-P-L-M-R-Q-W-I-G-F-D-K-L-A-N-A-L-Q-N-A-G-E-S-Q-S-F-P-P-Y-N-I-E-K-S-D-D-N-H-Y-R-I-T-L-A-L-A-G-F-R-Q-E-D-L-E-I-Q-L-E-G-T-R-L-S-V-K-G-T-P-E-Q-P-K-E-E-K-K-W-L-H-Q-G-L-M-N-Q-P-F-S-L-S-F-T-L-A-E-N-M-E-V-S-G-A-T-F-V-N-G-L-L-H-I-D-L-I-R-N-E-P-E-P-I-A-A-Q-R-I-A-I-S-E-R-P-A-L-N-S"} +{"text": "### FUNCTION Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-H-T-S-E-L-L-K-H-I-Y-D-I-N-L-S-Y-L-L-L-A-Q-R-L-I-V-Q-D-K-A-S-A-M-F-R-L-G-I-N-E-E-M-A-T-T-L-A-A-L-T-L-P-Q-M-V-K-L-A-E-T-N-Q-L-V-C-H-F-R-F-D-S-H-Q-T-I-T-L-L-T-Q-D-S-R-V-D-D-L-Q-Q-I-H-T-G-I-M-L-S-T-R-L-L-N-D-V-N-Q-P-E-E-A-L-R-K-K-R-A"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-N-I-T-A-T-V-L-L-A-F-G-M-S-M-D-A-F-A-A-S-I-G-K-G-A-T-L-H-K-P-K-F-S-E-A-L-R-T-G-L-I-F-G-A-V-E-T-L-T-P-L-I-G-W-G-M-G-M-L-A-S-R-F-V-L-E-W-N-H-W-I-A-F-V-L-L-I-F-L-G-G-R-M-I-I-E-G-F-R-G-A-D-D-E-D-E-E-P-R-R-R-H-G-F-W-L-L-V-T-T-A-I-A-T-S-L-D-A-M-A-V-G-V-G-L-A-F-L-Q-V-N-I-I-A-T-A-L-A-I-G-C-A-T-L-I-M-S-T-L-G-M-M-V-G-R-F-I-G-S-I-I-G-K-K-A-E-I-L-G-G-L-V-L-I-G-I-G-V-Q-I-L-W-T-H-F-H-G"} +{"text": "### FUNCTION Probably mediates the hydrolysis of some nucleoside diphosphate derivatives ### SEQUENCE -M-E-Y-R-S-L-T-L-D-D-F-L-S-R-F-Q-L-L-R-P-Q-I-N-R-E-T-L-N-H-R-Q-A-A-V-L-I-P-I-V-R-R-P-Q-P-G-L-L-L-T-Q-R-S-I-H-L-R-K-H-A-G-Q-V-A-F-P-G-G-A-V-D-D-T-D-A-S-V-I-A-A-A-L-R-E-A-E-E-E-V-A-I-P-P-S-A-V-E-V-I-G-V-L-P-P-V-D-S-V-T-G-Y-Q-V-T-P-V-V-G-I-I-P-P-D-L-P-Y-R-A-S-E-D-E-V-S-A-V-F-E-M-P-L-A-Q-A-L-H-L-G-R-Y-H-P-L-D-I-Y-R-R-G-D-S-H-R-V-W-L-S-W-Y-E-Q-Y-F-V-W-G-M-T-A-G-I-I-R-E-L-A-L-Q-I-G-V-K-P"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-G-T-L-L-A-F-D-F-G-T-K-S-I-G-V-A-V-G-Q-R-I-T-G-T-A-R-P-L-P-A-I-K-A-Q-D-G-T-P-D-W-N-L-I-E-R-L-L-K-E-W-Q-P-D-E-I-I-V-G-L-P-L-N-M-D-G-T-E-Q-P-L-T-A-R-A-R-K-F-A-N-R-I-H-G-R-F-G-V-E-V-K-L-H-D-E-R-L-S-T-V-E-A-R-S-G-L-F-E-Q-G-G-Y-R-A-L-N-K-G-K-I-D-S-A-S-A-V-I-I-L-E-S-Y-F-E-Q-G-Y"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-A-T-A-Q-Q-L-E-Y-L-K-N-S-I-K-S-I-Q-D-Y-P-K-P-G-I-L-F-R-D-V-T-S-L-L-E-D-P-K-A-Y-A-L-S-I-D-L-L-V-E-R-Y-K-N-A-G-I-N-K-V-V-G-T-E-A-R-G-F-L-F-G-A-P-V-A-L-G-L-G-V-G-F-V-P-V-R-K-P-G-K-L-P-R-E-T-I-S-E-T-Y-D-L-E-Y-G-T-D-Q-L-E-I-H-V-D-A-I-K-P-G-D-K-V-L-V-V-D-D-L-L-A-T-G-G-T-I-E-A-T-V-K-L-I-R-R-L-G-G-E-V-A-D-A-A-F-I-I-N-L-F-D-L-G-G-E-Q-R-L-E-K-Q-G-I-T-S-Y-S-L-V-P-F-P-G-H"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine ### SEQUENCE -M-L-I-F-E-G-K-E-I-E-T-D-T-E-G-Y-L-K-E-S-S-Q-W-S-E-P-L-A-V-V-I-A-E-N-E-G-I-S-L-S-P-E-H-W-E-V-V-R-F-V-R-D-F-Y-L-E-F-N-T-S-P-A-I-R-M-L-V-K-A-M-A-N-K-F-G-E-E-K-G-N-S-R-Y-L-Y-R-L-F-P-K-G-P-A-K-Q-A-T-K-I-A-G-L-P-K-P-V-K-C-I"} +{"text": "### FUNCTION Guanidinium ion exporter Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons ### SEQUENCE -M-S-W-I-I-L-V-I-A-G-L-L-E-V-V-W-A-V-G-L-K-Y-T-H-G-F-S-R-L-T-P-S-V-I-T-V-T-A-M-I-V-S-M-A-L-L-A-W-A-M-K-S-L-P-V-G-T-A-Y-A-V-W-T-G-I-G-A-V-G-A-A-I-T-G-I-V-L-L-G-E-S-A-N-P-M-R-L-A-S-L-A-L-I-V-L-G-I-I-G-L-K-L-S-T-H"} +{"text": "### FUNCTION An ATP-independent periplasmic chaperone, decreases protein aggregation and helps protein refolding Binds substrate over a large region Protect proteins in vitro against tannin inactivation ### SEQUENCE -M-R-K-L-T-A-L-F-V-A-S-T-L-A-L-G-A-A-N-L-A-H-A-A-D-T-T-T-A-A-P-A-D-A-K-P-M-M-H-H-K-G-K-F-G-P-H-Q-D-M-M-F-K-D-L-N-L-T-D-A-Q-K-Q-Q-I-R-E-I-M-K-G-Q-R-D-Q-M-K-R-P-P-L-E-E-R-R-A-M-H-D-I-I-A-S-D-T-F-D-K-A-K-A-E-A-Q-I-A-K-M-E-E-Q-R-K-A-N-M-L-A-H-M-E-T-Q-N-K-I-Y-N-I-L-T-P-E-Q-K-K-Q-F-N-A-N-F-E-K-R-L-T-E-R-P-A-A-K-G-K-M-P-A-T-A-E"} +{"text": "### FUNCTION Catalyzes the dephosphorylation of heptose of the outer membrane lipopolysaccharide core ### SEQUENCE -M-L-A-F-C-R-S-S-L-K-S-K-K-Y-F-I-I-L-L-A-L-A-A-I-A-G-L-G-T-H-A-A-W-S-S-N-G-L-P-R-I-D-N-K-T-L-G-R-L-A-Q-Q-H-P-V-V-V-L-F-R-H-A-E-R-C-D-R-S-T-N-Q-C-L-S-D-K-T-G-I-T-V-K-G-T-Q-D-A-R-E-L-G-N-A-F-S-A-D-I-P-D-F-D-L-Y-S-S-N-T-V-R-T-I-Q-S-A-T-W-F-S-A-G-K-K-L-T-V-D-K-R-L-L-Q-C-G-N-E-I-Y-S-A-I-K-D-L-Q-S-K-A-P-D-K-N-I-V-I-F-T-H-N-H-C-L-T-Y-I-A-K-D-K-R-D-A-T-F-K-P-D-Y-L-D-G-L-V-M-H-V-E-K-G-K-V-Y-L-D-G-E-F-V-N-H"} +{"text": "### FUNCTION General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases ### SEQUENCE -M-K-T-I-L-P-A-V-L-F-A-A-F-A-T-T-S-A-W-A-A-E-S-V-Q-P-L-E-K-I-A-P-Y-P-Q-A-E-K-G-M-K-R-Q-V-I-Q-L-T-P-Q-E-D-E-S-T-L-K-V-E-L-L-I-G-Q-T-L-E-V-D-C-N-L-H-R-L-G-G-K-L-E-S-K-T-L-E-G-W-G-Y-D-Y-Y-V-F-D-K-V-S-S-P-V-S-T-M-M-A-C-P-D-G-K-K-E-K-K-F-V-T-A-Y-L-G-D-T-G-M-L-R-Y-N-S-K-L-P-I-V-V-Y-T-P-D-N-V-D-V-K-Y-R-V-W-K-A-E-E-K-I-D-N-A-V-V-R"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-F-T-I-N-A-E-V-R-K-E-Q-G-K-G-A-S-R-R-L-R-A-A-N-K-F-P-A-I-I-Y-G-G-K-E-A-P-L-A-I-E-L-D-H-D-K-V-M-N-I-Q-A-K-A-E-F-Y-S-E-V-L-T-I-V-V-D-G-K-E-I-K-V-K-A-Q-D-V-Q-R-H-P-Y-K-P-K-L-Q-H-I-D-F-V-R-A"} +{"text": "### FUNCTION Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP ### SEQUENCE -M-N-F-L-A-H-L-H-L-A-H-L-A-E-S-S-L-S-G-N-L-L-A-D-F-V-R-G-N-P-E-E-S-F-P-P-D-V-V-A-G-I-H-M-H-R-R-I-D-V-L-T-D-N-L-P-E-V-R-E-A-R-E-W-F-R-S-E-T-R-R-V-A-P-I-T-L-D-V-M-W-D-H-F-L-S-R-H-W-S-Q-L-S-P-D-F-P-L-Q-E-F-V-C-Y-A-R-E-Q-V-M-T-I-L-P-D-S-P-P-R-F-I-N-L-N-N-Y-L-W-S-E-Q-W-L-V-R-Y-R-D-M-D-F-I-Q-N-V-L-N-G-M-A-S-R-R-P-R-L-D-A-L-R-D-S-W-Y-D-L-D-A-H-Y-A-A-L-E-T-R-F-W-Q-F-Y-P-R-M-M-A-Q-A-S-R-K-A-L"} +{"text": "### FUNCTION Catalyzes the excretion of spermidine ### SEQUENCE -M-F-Y-W-I-L-L-A-L-A-I-A-T-E-I-T-G-T-L-S-M-K-W-A-S-V-G-N-G-N-A-G-F-I-L-M-L-V-M-I-T-L-S-Y-I-F-L-S-F-A-V-K-K-I-A-L-G-V-A-Y-A-L-W-E-G-I-G-I-L-F-I-T-I-F-S-V-L-L-F-D-E-A-L-S-T-M-K-I-A-G-L-L-T-L-V-A-G-I-V-L-I-K-S-G-T-R-K-P-G-K-P-V-K-E-A-T-R-A-T-I"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-D-I-H-N-K-A-R-I-H-W-A-C-R-R-G-M-R-E-L-D-I-S-I-M-P-F-F-E-H-E-Y-D-S-L-S-D-E-E-K-R-I-F-V-R-L-L-Q-S-D-D-P-D-L-F-N-W-L-M-N-H-G-K-P-A-D-A-E-L-E-Q-M-V-R-L-I-Q-T-R-N-R-E-R-G-P-V-A-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-M-H-K-G-R-N-R-G-L-A-A-G-A-D-V-S-F-G-S-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-A-V-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-A-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-V-L-Y-E-M-D-G-V-P-E-E-L-A-R-E-A-F-K-L-A-A-A-K-L-P-I-K-T-T-F-V-T-K-T-V-M"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-S-K-E-Q-K-T-P-E-G-Q-A-P-E-E-I-I-M-D-Q-H-E-E-V-E-A-V-E-P-N-D-S-A-E-Q-V-D-P-R-D-E-K-I-A-N-L-E-V-Q-L-A-E-A-Q-T-R-E-R-D-T-V-L-R-I-K-A-E-M-E-N-L-R-R-R-T-E-Q-D-I-E-K-A-H-K-F-A-L-E-K-F-V-N-E-L-L-P-V-I-D-S-L-D-R-A-L-E-V-A-D-K-A-N-P-D-M-A-A-M-V-E-G-I-E-L-T-L-K-S-M-L-D-V-V-R-K-F-G-V-E-V-I-A-E-T-N-V-P-L-D-P-N-V-H-Q-A-I-A-M-V-E-S-E-E-V-P-A-G-N-V-L-G-I-M-Q-K-G-Y-T-L-N-G-R-T-I-R-A-A-M-V-T-V-A-K-A-K"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine ### SEQUENCE -M-L-I-F-E-G-K-E-I-S-T-D-S-E-G-Y-L-K-E-T-T-Q-W-S-E-A-L-A-V-A-I-A-A-N-E-G-I-E-L-S-A-E-H-W-E-V-V-R-F-V-R-E-F-Y-L-E-F-N-T-S-P-A-I-R-M-L-V-K-A-M-A-N-K-F-G-E-E-K-G-N-S-R-Y-L-Y-R-L-F-P-K-G-P-A-K-Q-A-T-K-I-A-G-L-P-K-P-V-K-C-I"} +{"text": "### FUNCTION Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP ### SEQUENCE -M-N-F-L-A-H-L-H-L-A-H-L-A-D-S-S-L-S-G-N-L-L-A-D-F-V-R-G-N-P-A-T-H-Y-P-P-D-V-V-E-G-I-Y-M-H-R-R-I-D-V-M-T-D-N-L-P-E-V-R-E-A-R-E-W-F-R-H-E-T-R-R-V-A-P-I-T-L-D-V-M-W-D-H-F-L-S-R-H-W-T-Q-I-S-P-D-F-P-L-Q-A-F-V-G-Y-A-H-A-Q-V-A-T-I-L-P-D-S-P-P-R-F-V-N-L-N-D-Y-L-W-S-E-K-W-L-E-R-Y-R-D-M-D-F-I-Q-N-V-L-N-G-M-A-N-R-R-P-R-L-D-A-L-R-D-S-W-Y-D-L-D-A-H-Y-D-A-L-E-E-R-F-W-H-F-Y-P-R-M-M-A-Q-A-A-R-K-A-L"} +{"text": "### FUNCTION Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins ### SEQUENCE -M-R-L-T-S-K-G-R-Y-A-V-T-A-M-L-D-V-A-L-N-S-E-A-G-P-V-P-L-A-D-I-S-E-R-Q-G-I-S-L-S-Y-L-E-Q-L-F-S-R-L-R-K-N-G-L-V-S-S-V-R-G-P-G-G-G-Y-L-L-G-K-D-A-G-S-I-A-V-G-E-V-I-S-A-V-D-E-S-V-D-A-T-R-C-Q-G-K-G-G-C-Q-G-G-D-K-C-L-T-H-A-L-W-R-D-L-S-D-R-L-T-G-F-L-N-N-I-T-L-G-E-L-V-N-N-Q-E-V-L-D-V-S-G-R-Q-H-T-H-D-A-P-R-A-S-G-R-A-Q-D-A-I-D-V-K-L-R-A"} +{"text": "### FUNCTION Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress ### SEQUENCE -M-I-A-S-K-F-G-I-G-Q-Q-V-R-H-S-L-L-G-Y-L-G-V-V-V-D-I-D-P-E-Y-S-L-D-E-P-S-P-D-E-L-A-V-N-D-E-L-R-A-A-P-W-Y-H-V-V-M-E-D-D-D-G-Q-P-V-H-T-Y-L-A-E-A-Q-L-R-S-E-M-R-D-E-H-P-E-Q-P-S-M-D-E-L-A-R-T-I-R-K-Q-L-Q-A-P-R-L-R-N"} +{"text": "### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-T-G-I-Q-I-T-K-A-A-N-D-D-L-L-N-S-F-W-L-L-D-S-E-K-G-E-A-R-C-I-V-A-K-S-G-F-A-E-D-E-V-V-A-V-S-K-L-G-E-I-E-Y-R-E-I-P-M-E-V-K-P-E-V-R-V-E-G-G-Q-H-L-N-V-N-V-L-R-R-E-T-L-E-D-A-V-K-H-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-A-R-T-F-T-E-S-L"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-F-T-I-N-A-E-V-R-K-E-Q-G-K-G-A-S-R-R-L-R-A-A-N-K-F-P-A-I-I-Y-G-G-S-E-A-P-I-A-I-E-L-D-H-D-Q-V-M-N-M-Q-A-K-A-E-F-Y-S-E-V-L-T-L-V-V-D-G-K-E-V-K-V-K-A-Q-A-V-Q-R-H-A-Y-K-P-K-L-T-H-I-D-F-V-R-A"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-D-D-V-A-L-P-L-Q-F-T-D-A-A-A-N-K-V-K-S-L-I-A-D-E-D-N-P-N-L-K-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-D-Q-V-N-E-G-D-M-T-I-E-K-Q-G-V-G-L-V-V-D-P-M-S-L-Q-Y-L-V-G-G-S-V-D-Y-T-E-G-L-E-G-S-R-F-I-V-T-N-P-N-A-K-S-T-C-G-C-G-S-S-F-S-I"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-K-I-I-K-D-A-L-A-G-T-L-E-S-S-D-V-M-I-R-I-G-P-S-S-E-P-G-I-R-L-E-L-E-S-L-V-K-Q-Q-F-G-A-A-I-E-Q-V-V-R-E-T-L-A-K-L-G-V-E-R-A-L-V-S-V-D-D-K-G-A-L-E-C-I-L-R-A-R-V-Q-A-A-A-L-R-A-A-E-Q-T-E-I-Q-W-S-A-L"} +{"text": "### FUNCTION Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base The complementary strand guanine functions in substrate recognition Required for DNA damage lesion repair in stationary-phase cells ### SEQUENCE -M-V-K-D-I-L-A-P-G-L-R-V-V-F-C-G-I-N-P-G-L-S-S-A-N-T-G-F-P-F-A-H-P-A-N-R-F-W-K-V-I-H-L-A-G-F-T-D-R-Q-L-K-P-E-E-A-E-K-L-L-D-F-R-C-G-V-T-K-L-V-D-R-P-T-V-Q-A-T-E-V-K-L-H-E-L-R-S-G-G-R-N-L-I-E-K-I-E-D-Y-Q-P-A-A-L-A-V-L-G-K-Q-A-F-E-Q-G-F-S-Q-R-G-I-A-W-G-K-Q-K-I-A-I-G-A-T-M-V-W-V-L-P-N-P-S-G-L-N-R-I-K-T-E-K-L-V-E-A-Y-R-E-L-D-Q-A-L-I-M-R-G-L"} +{"text": "### FUNCTION Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein ### SEQUENCE -M-K-S-N-R-Q-A-R-H-I-L-G-L-D-Y-R-I-S-N-Q-R-K-V-V-T-E-G-D-T-S-S-V-V-N-N-P-T-G-R-K-R-R-A-D-S-Q-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-E-F-V-T-V-A-R-P-Y-A-K-A-A-F-D-F-A-V-E-H-Q-S-V-E-R-W-Q-D-M-L-A-F-A-A-E-V-T-K-N-E-Q-M-A-E-L-L-S-G-A-L-A-P-E-T-L-A-E-S-F-I-A-V-C-G-E-Q-L-D-E-N-G-Q-N-L-I-R-V-M-A-E-N-N-R-L-N-A-L-P-D-V-L-E-Q-F-I-H-L-R-A-A-S-E-A-T-S-E-V-E-V-T-S-A-T-A-L-S-E-E-Q-L-S-K-I-S-A-A-M-E-K-R-L-S-R-K-V-K-L-N-C-K-I-D-K-S-V-M-A-G-V-I-I-R-A-G-D-M-V-I-D-G-S-V-R-G-R-L-E-R-L-A-D-V-L-Q-S"} +{"text": "### FUNCTION Is able to transfer iron-sulfur clusters to apo-ferredoxin Multiple cycles of cluster formation and transfer are observed, suggesting that IscA acts catalytically Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB ### SEQUENCE -M-S-I-T-L-S-D-S-A-A-A-R-V-N-T-F-L-A-N-R-G-K-G-F-G-L-R-L-G-V-R-T-S-G-C-S-G-M-A-Y-V-L-E-F-V-D-E-P-T-A-E-D-T-V-F-E-D-K-G-V-K-V-V-V-D-G-K-S-L-Q-F-L-D-G-T-Q-L-D-F-V-K-E-G-L-N-E-G-F-K-F-S-N-P-N-V-K-D-E-C-G-C-G-E-S-F-H-V"} +{"text": "### FUNCTION This protein is involved in control of the biosynthesis of threonine ### SEQUENCE -M-N-R-I-S-T-T-T-I-T-T-I-T-I-T-T-G-N-G-A-G"} +{"text": "### FUNCTION Catalyzes the excretion of spermidine ### SEQUENCE -M-Q-Q-F-E-W-I-H-G-A-W-L-G-L-A-I-M-L-E-I-A-A-N-V-L-L-K-F-S-D-G-F-R-R-K-C-Y-G-I-L-S-L-A-A-V-L-A-A-F-S-A-L-S-Q-A-V-K-G-I-D-L-S-V-A-Y-A-L-W-G-G-F-G-I-A-A-T-L-A-A-G-W-V-L-F-G-Q-R-L-N-P-K-G-W-V-G-V-I-L-L-L-A-G-M-V-M-I-K-F-A"} +{"text": "### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate and magnesium starvation, but also in stationary phase and during nitrogen starvation Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway ### SEQUENCE -M-K-N-L-I-A-E-L-L-L-K-L-A-Q-K-E-E-E-S-K-E-L-V-A-Q-V-E-A-L-E-I-I-V-T-A-M-L-R-N-M-A-Q-N-E-Q-E-M-L-I-R-Q-V-E-G-A-L-E-G-V-K-P-D-A-S-V-P-D-H-D-T-E-L-L-R-Q-Y-V-K-K-L-L-R-H-P-R-H"} +{"text": "### FUNCTION May function as a transcriptional regulator that controls feoABC expression ### SEQUENCE -M-A-S-L-I-Q-V-R-D-L-L-A-L-R-G-R-M-E-A-T-Q-I-S-H-T-L-H-A-P-Q-P-M-I-D-A-M-L-N-Q-L-E-I-M-G-K-A-V-R-I-P-E-E-P-D-G-C-L-S-G-S-C-K-S-C-P-E-G-K-A-C-L-R-E-W-W-A-L-R"} +{"text": "### FUNCTION PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP ### SEQUENCE -M-K-K-F-R-W-V-V-L-G-I-V-V-V-V-C-L-L-L-W-A-Q-V-F-N-I-M-C-D-Q-D-V-Q-F-F-S-G-I-C-A-I-N-K-F-I-P-W"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-E-Q-T-M-L-N-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-G-V-G-D-I-I-K-I-T-I-K-E-A-I-P-R-G-K-V-K-K-G-D-V-L-K-A-V-V-V-R-T-K-K-G-V-R-R-P-D-G-S-V-I-R-F-D-G-N-A-C-V-I-L-N-N-N-S-E-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-N-E-K-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-S-E-G-Q-T-V-R-L-E-K-L-D-I-A-T-G-E-T-I-E-F-A-E-V-L-M-I-A-N-G-E-E-V-K-I-G-V-P-F-V-D-G-G-V-I-K-A-E-V-V-A-H-G-R-G-E-K-V-K-I-V-K-F-R-R-R-K-H-Y-R-K-Q-Q-G-H-R-Q-W-F-T-D-V-K-I-T-G-I-S-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-L-N-A-T-I-L-G-Q-A-I-A-F-I-L-F-V-W-F-C-M-K-Y-V-W-P-P-L-M-A-A-I-E-K-R-Q-K-E-I-A-D-G-L-A-S-A-E-R-A-H-K-D-L-D-L-A-K-A-S-A-T-D-Q-L-K-K-A-K-A-E-A-Q-V-I-I-E-Q-A-N-K-R-R-A-Q-I-L-D-E-A-K-T-E-A-E-Q-E-R-T-K-I-V-A-Q-A-Q-A-E-I-E-A-E-R-K-R-A-R-E-E-L-R-K-Q-V-A-I-L-A-V-A-G-A-E-K-I-I-E-R-S-V-D-E-A-A-N-S-D-I-V-D-K-L-V-A-E-L"} +{"text": "### FUNCTION Involved in resistance toward heavy metals ### SEQUENCE -M-L-D-V-K-S-Q-D-I-S-I-P-E-A-V-V-V-L-C-T-A-P-D-E-A-T-A-Q-D-L-A-A-K-V-L-A-E-K-L-A-A-C-A-T-L-L-P-G-A-T-S-L-Y-Y-W-E-G-K-L-E-Q-E-Y-E-V-Q-M-I-L-K-T-T-V-S-H-Q-Q-A-L-I-D-C-L-K-S-H-H-P-Y-Q-T-P-E-L-L-V-L-P-V-T-H-G-D-T-D-Y-L-S-W-L-N-A-S-L-R"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-E-Q-N-N-T-E-M-A-F-Q-I-Q-R-I-Y-T-K-D-V-S-F-E-A-P-N-A-P-H-V-F-Q-K-D-W-Q-P-E-V-K-L-D-L-D-T-A-S-S-Q-L-A-D-D-V-Y-E-V-V-L-R-V-T-V-T-A-S-L-G-E-E-T-A-F-L-C-E-V-Q-Q-A-G-I-F-S-I-S-G-I-E-G-T-Q-M-A-H-C-L-G-A-Y-C-P-N-I-L-F-P-Y-A-R-E-C-I-T-S-L-V-S-R-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-M-N-Y-L-Q-Q-Q-A-G-E-G-T-E-E-H-Q-D-A"} +{"text": "### FUNCTION Binds to H-NS and modified the range of genes it silences ### SEQUENCE -M-T-V-Q-D-Y-L-L-K-F-R-K-I-S-S-L-E-S-L-E-K-L-F-D-H-L-N-Y-T-L-T-D-D-M-D-I-V-N-M-Y-R-A-A-D-H-R-R-A-E-L-V-S-G-G-R-L-F-D-V-G-Q-V-P-Q-S-V-W-R-Y-V-Q"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-R-E-E-R-L-L-K-V-L-R-A-P-H-V-S-E-K-A-S-T-A-M-E-K-T-N-T-I-V-L-K-V-A-K-D-A-T-K-A-E-I-K-A-A-V-Q-K-L-F-E-V-E-V-E-V-V-N-T-L-V-V-K-G-K-V-K-R-H-G-Q-R-I-G-R-R-S-D-W-K-K-A-Y-V-T-L-K-E-G-Q-N-L-D-F-V-G-G-A-E"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-K-I-N-Q-L-A-V-A-G-T-L-E-S-G-D-V-M-I-R-I-A-P-L-D-T-Q-D-I-D-L-Q-I-N-S-S-V-E-K-Q-F-G-E-A-I-R-A-T-I-L-E-V-L-S-R-Y-D-V-R-G-V-Q-L-N-V-D-D-K-G-A-L-D-C-I-L-R-A-R-L-E-T-L-L-A-R-A-S-G-I-A-A-L-P-W-E-D-R-Q"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-S-A-R-I-R-R-A-T-R-A-R-R-K-L-K-E-L-G-A-T-R-L-V-V-H-R-T-P-R-H-I-Y-A-Q-V-I-A-P-N-G-S-E-V-L-V-A-A-S-T-V-E-K-A-I-A-E-Q-L-K-Y-T-G-N-K-D-A-A-A-A-V-G-K-A-V-A-E-R-A-L-E-K-G-I-K-D-V-S-F-D-R-S-G-F-Q-Y-H-G-R-V-Q-A-L-A-D-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-S-A-Q-P-V-D-I-Q-I-F-G-R-S-L-R-V-N-C-P-P-D-Q-R-D-A-L-N-Q-A-A-D-D-L-N-Q-R-L-Q-D-L-K-V-R-T-R-V-T-N-T-E-Q-L-V-F-I-A-A-L-N-I-S-Y-E-L-T-Q-E-K-A-K-T-R-D-Y-A-A-S-M-E-Q-R-I-R-M-L-Q-Q-T-I-E-Q-A-L-L-D-Q-G-R-I-T-E-K-T-G-Q-N-F-E"} +{"text": "### FUNCTION Guanidinium ion exporter Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons ### SEQUENCE -M-S-W-I-I-L-L-I-A-G-L-L-E-V-V-W-A-V-G-L-K-Y-T-H-G-F-S-R-L-T-P-S-I-I-T-I-T-A-M-V-I-S-M-A-L-L-S-W-A-M-K-T-L-P-V-G-T-A-Y-A-I-W-T-G-I-G-A-V-G-A-A-I-T-G-I-L-L-L-G-E-S-A-S-P-A-R-L-L-S-L-G-L-I-V-A-G-I-I-G-L-K-L-S-A-H"} +{"text": "### FUNCTION Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE Its activity is ATP-independent ### SEQUENCE -M-R-N-F-D-L-S-P-L-Y-R-S-A-I-G-F-D-R-L-F-N-L-L-E-N-N-Q-S-Q-S-N-G-G-Y-P-P-Y-N-V-E-L-V-D-E-N-H-Y-R-I-A-I-A-V-A-G-F-A-E-S-E-L-E-I-T-A-Q-D-N-L-L-V-V-K-G-A-H-A-D-E-Q-K-E-R-T-Y-L-Y-Q-G-I-A-E-R-N-F-E-R-K-F-Q-L-A-E-N-I-H-V-R-G-A-N-L-V-N-G-L-L-Y-I-E-L-E-R-V-I-P-E-A-N-K-P-R-R-I-E-I-N"} +{"text": "### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-T-L-P-S-G-H-P-K-S-R-L-I-K-K-F-T-A-L-G-P-Y-I-R-E-G-Q-C-E-D-N-R-F-F-F-D-C-L-A-V-C-V-N-V-K-P-A-P-E-K-R-E-F-W-G-W-W-M-E-L-E-A-Q-E-K-R-F-T-Y-R-Y-Q-F-G-L-F-D-K-E-G-N-W-T-V-V-P-I-N-E-T-E-V-V-E-R-L-E-Y-T-L-R-E-F-H-E-K-L-R-D-L-L-I-S-M-E-L-A-L-E-P-S-D-D-F-N-D-E-P-V-K-L-S-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-L-L-S-L-R-K-N-N-E-F-R-T-V-Y-R-R-G-K-S-Y-A-N-D-L-L-V-L-Y-V-Y-P-N-R-K-N-V-T-K-D-G-E-R-F-N-K-V-G-V-S-V-S-K-K-V-G-K-S-V-V-R-S-R-V-K-R-L-I-L-E-N-Y-R-L-N-S-S-E-L-K-E-G-Y-D-F-V-F-I-A-R-V-A-I-N-G-K-D-F-K-Q-V-G-K-A-M-N-N-L-I-K-K-A-G-L-R-D-N-E-K-I-V-H-S-N-D"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-K-Y-E-T-I-F-V-A-H-P-S-L-D-E-E-A-V-K-A-L-I-E-K-F-K-G-V-I-E-N-G-N-G-T-V-D-N-V-D-F-W-G-K-R-K-L-A-Y-E-I-A-K-V-N-E-G-Y-Y-T-L-I-N-F-T-A-N-P-E-L-P-K-E-L-D-R-V-F-G-I-T-D-G-I-I-R-H-I-I-V-K-E-E-Q"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-N-V-K-R-G-G-K-F-R-R-A-R-K-K-V-C-I-F-C-V-D-K-A-E-S-I-D-Y-K-D-V-A-K-L-K-K-Y-I-T-E-R-G-K-I-L-P-R-R-I-S-G-T-C-A-K-H-Q-R-Q-L-T-D-A-I-K-R-S-R-N-I-A-L-L-P-F-T-T-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-L-Q-D-V-K-K-L-G-K-K-G-D-V-I-N-A-S-D-G-Y-A-R-N-F-L-F-P-K-K-L-A-Q-E-A-T-D-N-N-L-H-I-L-N-N-K-K-E-N-E-R-R-Q-K-L-A-E-L-E-A-A-Q-A-L-A-A-D-L-K-D-K-V-I-K-I-D-G-K-A-G-D-N-G-K-L-F-G-A-I-T-S-K-D-V-A-G-L-I-K-K-Q-F-N-V-E-V-D-K-K-K-I-V-M-D-T-I-K-I-A-G-T-Y-N-I-E-V-K-L-Y-P-E-V-S-T-K-M-K-V-M-V-V-P-V-Q"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-N-I-T-V-I-S-V-G-K-L-K-E-K-Y-L-K-Q-A-I-D-E-Y-S-K-R-L-S-R-Y-C-K-L-E-I-I-E-L-P-D-E-K-T-P-D-N-A-S-E-K-E-E-L-Q-I-K-E-K-E-G-K-L-I-L-S-K-I-K-D-N-M-H-V-I-A-M-D-L-K-G-N-E-I-T-S-E-K-F-S-K-Y-I-E-N-C-G-V-M-G-N-S-N-I-T-F-V-I-G-G-S-L-G-L-S-Q-E-V-I-K-R-A-D-Y-K-L-C-F-S-K-M-T-F-P-H-Q-L-F-R-V-M-L-L-E-Q-V-Y-R-A-F-R-I-M-K-N-E-P-Y-H-K"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-K-K-I-I-L-A-G-G-C-F-W-G-V-E-E-F-L-S-R-I-N-G-V-V-S-T-E-V-G-Y-A-N-G-R-T-E-N-P-T-Y-E-D-I-C-T-K-N-T-Y-F-A-E-V-C-L-V-N-Y-D-E-N-I-I-S-L-K-E-L-L-A-K-F-W-T-I-I-D-P-T-S-L-N-K-Q-G-N-D-V-G-S-Q-Y-R-T-G-I-Y-Y-V-D-S-S-D-L-E-D-I-L-N-S-K-E-E-L-Q-K-S-Y-S-K-K-I-V-T-E-V-K-P-L-E-N-Y-Y-K-A-E-E-Y-H-Q-K-Y-L-K-K-N-P-N-G-Y-C-H-I-K-L-D"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-I-L-I-V-G-L-G-N-P-G-K-Q-Y-E-Q-T-R-H-N-I-G-F-D-V-I-D-Y-M-A-N-K-Y-N-I-D-V-N-R-E-K-F-K-G-I-C-G-E-G-F-I-E-N-K-K-V-I-L-L-K-P-L-T-Y-M-N-L-S-G-E-S-I-R-E-L-A-N-F-Y-K-L-E-D-D-E-I-I-V-V-Y-D-D-I-S-L-D-I-G-R-L-R-I-R-E-K-G-S-A-G-G-H-N-G-I-K-S-I-I-Q-N-L-G-G-D-K-F-P-R-V-K-V-G-V-G-Q-P-K-D-N-L-V-N-H-V-L-G-K-F-S-K-E-D-R-E-H-I-E-K-V-I-P-V-V-S-D-A-I-V-E-I-V-K-N-D-A-K-E-S-M-N-K-F-N-G-V-N-I-E"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-E-K-K-H-I-M-T-Y-E-G-V-K-K-L-E-D-E-L-E-Y-L-K-T-V-K-R-K-E-I-T-E-K-I-K-V-A-L-G-Y-G-D-L-S-E-N-S-E-Y-D-E-A-K-N-E-Q-A-F-T-E-G-R-I-I-Q-L-E-N-M-L-K-N-A-V-V-V-D-E-S-E-I-S-T-D-I-V-T-V-G-S-I-V-K-V-M-D-F-D-F-D-E-E-V-E-Y-S-I-V-G-S-A-E-A-D-P-M-N-F-K-I-S-N-E-S-P-V-G-E-G-L-M-G-K-K-V-G-D-V-V-E-I-E-V-P-G-G-T-T-K-F-E-V-L-G-I-R-R"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-T-G-M-I-K-L-Q-L-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-G-F-C-K-E-F-N-A-K-T-A-D-K-A-G-L-I-I-P-V-V-I-T-V-Y-Q-D-R-S-F-S-F-I-L-K-T-P-P-A-A-V-L-I-K-K-E-L-G-L-E-S-G-S-G-V-P-N-R-T-K-V-G-N-I-T-K-E-Q-I-R-K-I-A-E-L-K-M-P-D-L-N-A-A-T-I-E-T-A-M-S-M-I-E-G-T-A-R-S-M-G-V-V-V-V-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-D-T-V-N-K-N-R-Q-L-K-E-A-K-V-A-E-I-K-E-K-L-E-K-A-Q-S-V-V-L-A-S-Y-Q-G-L-T-V-E-Q-D-T-N-L-R-K-S-L-R-E-A-G-V-E-Y-K-V-Y-K-N-T-L-V-T-L-A-A-K-E-L-G-F-D-G-I-V-E-Y-L-E-G-P-V-S-I-A-F-G-Y-E-D-A-T-A-P-A-R-I-L-N-D-F-A-K-E-N-K-K-L-E-L-K-A-A-I-V-E-G-T-V-Y-N-K-E-Q-T-E-Q-L-A-A-I-P-S-R-E-V-L-L-A-K-L-L-G-S-I-K-S-P-L-S-N-F-A-Y-L-L-S-A-I-A-D-K-K-E-E-S-A-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-T-K-E-Q-I-I-G-A-L-K-E-M-S-V-L-E-L-N-E-V-V-K-A-C-E-E-E-F-G-V-S-A-A-A-P-V-A-V-V-G-G-A-A-A-G-A-A-A-E-E-K-S-E-F-D-V-V-L-T-N-A-G-A-N-K-I-K-V-I-K-A-V-R-E-L-T-G-L-G-L-K-E-A-K-E-I-V-D-G-A-P-K-T-L-K-E-A-V-A-K-E-E-A-E-D-M-K-A-K-L-A-E-V-G-A-E-V-E-L-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-S-Q-L-V-R-K-G-R-K-T-V-A-S-K-S-T-A-P-A-L-K-E-C-P-Q-K-R-G-V-C-T-V-V-K-T-T-T-P-K-K-P-N-S-A-L-R-K-I-A-R-V-R-L-T-N-G-Y-E-V-T-A-Y-I-P-G-V-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-S-A-G-V-A-N-R-M-Q-G-R-S-K-Y-G-A-K-K-P-K-Q-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-H-I-A-K-R-D-V-L-P-D-P-V-Y-N-S-K-V-V-T-K-L-I-N-N-V-M-E-D-G-K-K-G-V-A-Q-K-I-C-Y-D-A-F-Q-I-I-N-E-K-T-G-R-D-A-M-E-V-F-E-E-A-M-N-N-I-M-P-L-L-E-V-K-A-R-R-I-G-G-A-N-Y-Q-V-P-I-E-V-R-P-E-R-R-Q-T-L-G-L-R-W-L-L-A-A-S-R-K-R-G-E-K-Y-M-R-E-R-L-A-G-E-L-M-D-A-A-N-N-T-G-A-A-V-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-Y"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-K-Q-K-I-R-I-R-L-K-A-F-D-H-T-I-L-D-Q-S-A-E-K-I-V-E-T-A-K-S-T-G-A-K-V-V-G-P-V-P-L-P-T-E-K-D-V-I-T-I-L-R-A-V-H-K-Y-K-D-S-R-E-Q-F-E-V-R-T-H-K-R-L-I-D-I-V-N-P-S-P-K-T-V-D-A-L-M-R-L-N-L-P-A-G-V-D-I-E-I-K-L"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-K-L-T-S-H-D-I-I-R-K-P-V-I-T-E-K-S-M-A-A-M-A-E-N-K-Y-T-F-I-V-H-M-A-A-N-K-V-Q-I-K-R-A-V-E-E-V-F-N-V-K-V-A-D-V-K-T-M-R-F-E-G-K-T-K-R-V-G-V-H-I-G-K-R-A-D-F-K-K-A-V-I-T-L-A-E-G-S-S-I-E-F-F-E-G-M-Q"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-I-K-K-G-P-F-V-H-A-G-L-L-K-K-I-E-E-M-N-Q-N-G-D-K-K-V-I-K-T-W-S-R-S-S-T-I-F-P-Q-M-I-G-H-T-I-A-V-H-D-G-R-K-H-I-P-V-Y-V-T-E-D-M-V-G-H-K-L-G-E-F-V-L-T-R-T-F-K-G-H-I-K-N-E-K-T-S-K-R-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-I-A-K-Y-V-R-M-S-P-T-K-V-G-V-V-L-D-L-I-R-G-K-N-V-N-E-A-F-A-I-L-K-Y-T-P-R-D-A-A-E-V-I-S-K-V-L-K-S-A-V-A-N-A-E-N-N-H-E-L-D-A-N-R-L-F-V-A-E-A-H-V-G-H-G-P-T-L-K-R-F-R-P-M-D-H-G-K-A-F-R-I-N-K-R-T-S-N-I-T-L-V-V-K-E-R-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-H-R-K-V-Q-R-G-R-M-K-G-K-A-T-R-G-N-F-L-A-Y-G-D-F-G-I-Q-A-T-T-C-G-W-I-T-S-N-Q-I-E-A-A-R-I-A-I-N-R-Y-I-R-R-G-G-K-L-W-I-K-I-F-P-D-K-P-V-T-E-K-P-A-E-T-R-M-G-S-G-K-G-S-V-E-Y-W-V-A-V-V-K-P-G-R-V-L-F-E-L-S-G-V-D-E-E-K-A-R-E-A-M-R-L-A-S-H-K-L-P-V-K-T-K-F-V-T-R-R-D-F-E-E-M-G-G-E-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-N-L-R-K-K-R-L-G-R-V-V-S-D-K-M-D-K-T-I-V-V-A-V-E-T-K-V-R-H-P-L-Y-G-K-T-V-N-R-T-T-K-F-K-A-H-D-E-N-N-E-A-R-F-G-D-R-V-L-I-M-E-T-R-P-L-S-K-D-K-R-W-R-L-V-E-I-V-E-K-A-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-Q-T-L-L-K-V-A-D-N-S-G-A-K-E-I-M-C-I-R-V-L-G-G-S-K-R-K-F-G-N-I-G-D-V-I-V-A-S-V-K-S-A-T-P-G-G-V-V-K-K-G-E-V-V-K-A-V-I-V-R-S-V-R-G-L-R-R-A-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-K-D-D-K-Q-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-N-E-F-N-K-I-L-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-V-H-V-R-K-N-D-T-V-V-V-I-S-G-K-D-K-G-K-T-G-E-V-L-R-V-I-P-K-T-G-K-V-V-V-K-G-V-N-L-V-K-K-H-Q-K-P-N-R-Q-N-M-Q-G-G-I-I-E-M-E-A-A-I-N-S-S-K-V-M-L-F-C-E-K-C-K-K-A-T-R-I-S-H-K-L-L-E-D-G-A-K-V-R-V-C-K-K-C-G-E-T-F"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-Q-E-R-Y-E-K-E-V-V-P-A-M-M-E-K-F-G-Y-K-N-I-M-Q-V-P-K-I-E-K-V-V-I-N-M-G-V-G-E-A-K-D-N-P-K-V-L-E-S-A-V-S-D-L-Q-I-I-A-G-Q-K-P-V-L-T-R-A-K-K-S-V-A-N-F-K-I-R-E-N-M-A-L-G-C-K-V-T-L-R-K-T-N-M-Y-E-F-V-D-K-L-V-S-I-A-L-P-R-V-R-D-F-R-G-V-S-A-K-A-F-D-G-R-G-N-Y-S-L-G-I-K-E-Q-L-I-F-P-E-I-E-Y-D-K-V-D-K-V-R-G-M-D-I-I-F-V-T-S-A-N-T-D-E-E-A-R-E-L-L-R-F-L-G-M-P-F-A-Q"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-R-K-A-M-I-E-K-W-K-K-E-P-K-Y-K-T-R-A-Y-T-R-C-R-L-C-G-R-P-H-S-V-L-K-K-F-G-I-C-R-I-C-F-R-E-L-A-Y-K-G-E-I-P-G-C-R-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-L-L-T-R-V-R-N-A-N-S-V-R-H-E-V-V-E-V-P-S-S-S-V-K-K-A-I-V-N-I-L-L-Q-E-G-Y-L-K-G-V-E-E-Y-N-D-G-V-V-P-M-M-R-L-T-L-K-Y-G-A-N-N-E-R-V-I-T-G-L-K-R-I-S-K-P-G-L-R-V-Y-C-K-K-D-E-V-P-R-V-L-N-G-L-G-I-A-L-I-S-T-S-K-G-L-V-V-D-R-E-A-R-K-L-G-L-G-G-E-V-I-C-Y-V-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-M-P-I-A-I-P-A-G-V-T-V-T-V-T-P-E-N-V-V-T-V-K-G-P-K-G-E-L-V-K-A-M-H-K-D-I-N-I-A-V-E-D-A-Q-V-V-V-T-R-P-S-D-V-K-E-H-R-A-L-H-G-L-T-R-A-L-L-N-N-M-V-V-G-V-S-Q-G-F-S-K-T-L-E-L-N-G-V-G-Y-R-A-Q-L-Q-G-K-K-L-V-M-N-L-G-Y-S-H-P-V-E-V-E-A-V-D-G-V-D-F-K-L-D-G-T-T-K-V-I-V-E-G-I-D-K-E-K-V-G-A-V-A-A-N-I-R-S-W-R-K-P-E-P-Y-K-G-K-G-I-K-Y-S-D-E-V-I-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-F-K-K-A-D-R-K-E-A-R-E-R-R-H-L-R-V-R-K-K-V-F-G-T-P-E-R-P-R-L-S-V-Y-R-S-E-K-N-I-Y-A-Q-I-I-D-D-V-N-A-V-T-L-V-A-A-S-S-L-D-K-A-I-E-V-K-G-S-N-K-E-A-A-K-L-V-G-E-L-V-A-K-R-A-I-E-K-G-I-N-D-V-V-F-D-R-G-G-Y-V-Y-H-G-R-V-E-A-L-A-S-G-A-R-E-A-G-L-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-R-I-D-P-S-T-L-D-L-K-E-K-V-V-S-I-S-R-V-T-K-V-V-K-G-G-R-N-F-R-F-S-A-L-V-V-V-G-D-E-N-G-H-V-G-V-G-T-G-K-S-I-E-I-P-E-A-I-R-K-G-I-E-D-A-K-K-N-L-V-E-V-S-I-V-G-T-T-V-P-H-E-I-H-G-K-F-G-T-G-D-V-L-I-M-P-A-T-E-G-T-G-V-I-A-G-G-P-A-R-S-V-L-E-L-A-G-L-K-D-V-R-A-K-S-L-G-S-N-N-P-R-N-M-V-K-A-T-I-N-G-L-A-N-L-R-T-A-E-D-I-A-K-L-R-G-K-S-V-E-E-I-I-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-R-P-A-A-G-S-K-S-A-P-K-R-V-G-R-G-T-G-S-G-L-G-R-N-A-G-K-G-E-K-G-Q-N-A-R-S-G-G-G-V-R-P-G-F-E-G-G-Q-M-P-L-Y-R-R-L-P-K-R-G-F-T-N-P-F-T-K-H-F-V-T-I-N-V-D-R-L-N-I-F-D-N-G-T-E-V-T-P-E-L-L-L-E-R-R-V-V-S-K-L-M-D-G-V-K-I-L-G-N-G-N-I-E-K-S-L-T-I-A-G-C-K-L-S-K-Q-A-A-E-K-I-V-A-A-G-G-K-V-E-V-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-S-D-I-I-E-M-Q-G-T-V-L-E-A-L-P-N-A-M-F-E-V-E-L-E-S-G-H-K-I-L-A-H-I-S-G-K-L-R-M-N-F-I-R-I-L-P-G-D-K-V-T-V-E-L-S-P-Y-D-L-T-R-G-R-I-T-W-R-A-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-D-L-P-R-E-K-R-V-E-I-G-L-T-Y-I-Y-G-I-G-L-P-T-S-Q-K-I-L-E-V-T-G-V-N-P-D-T-R-V-K-D-L-T-E-E-E-V-N-S-I-R-N-Y-I-K-D-L-T-V-E-G-D-L-R-R-E-V-A-L-N-I-K-R-L-V-E-I-G-S-Y-R-G-I-R-H-R-K-G-L-P-L-R-G-Q-K-T-K-T-N-A-R-T-R-K-G-P-K-K-T-I-A-N-K-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-A-Q-K-V-K-K-T-R-R-R-K-E-R-K-N-V-E-H-G-A-A-H-I-Q-S-T-F-N-N-S-I-V-T-L-T-D-A-K-G-N-A-L-A-W-A-S-A-G-G-L-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-T-A-A-K-A-A-M-E-H-G-L-K-S-V-E-V-Y-V-K-G-P-G-A-G-R-E-A-A-I-R-S-L-Q-A-A-G-L-E-V-T-L-I-K-D-V-T-P-I-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-S-Y-I-A-K-A-Q-E-V-E-R-K-W-Y-V-V-D-A-A-G-K-P-L-G-R-V-A-S-Q-V-A-S-I-L-R-G-K-N-K-P-T-F-T-P-N-V-D-C-G-D-F-V-I-V-I-N-A-E-K-V-V-L-T-G-K-K-L-D-Q-K-M-L-R-K-H-S-L-Y-A-G-G-L-K-E-T-P-Y-R-E-V-L-E-K-K-P-E-F-A-F-E-E-A-V-R-R-M-L-P-T-G-V-L-G-R-K-M-L-K-K-L-N-V-Y-R-G-A-E-H-N-H-A-A-Q-K-P-E-V-L-E-L-R-Y"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-K-M-M-G-P-R-F-K-M-C-R-R-L-G-L-N-V-V-G-H-P-K-A-M-K-R-A-G-R-G-T-S-R-A-D-K-K-L-S-D-Y-G-I-Q-L-L-E-K-Q-R-L-R-A-Y-Y-G-V-M-E-R-Q-F-T-R-Y-V-D-Q-A-F-N-S-K-E-Q-P-G-E-A-L-L-M-I-L-E-S-R-L-D-N-M-V-Y-R-M-G-F-A-S-S-I-R-Q-A-R-Q-M-V-N-H-G-H-F-L-V-N-G-K-K-V-N-I-P-S-F-R-L-N-I-G-D-E-V-V-L-R-E-K-S-R-K-T-E-M-F-V-N-N-F-K-D-S-I-G-S-E-V-P-Y-V-S-K-E-E-D-N-F-K-G-I-F-T-R-K-P-K-R-E-E-I-P-I-T-I-Q-E-Q-L-I-V-E-F-Y-S-K"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-R-Q-G-I-H-P-E-Y-H-H-D-T-V-V-K-C-A-C-G-N-T-F-T-T-G-S-V-K-P-E-L-K-V-E-I-C-S-K-C-H-P-F-F-T-G-K-Q-K-I-V-D-V-G-G-R-V-D-K-F-N-K-R-F-N-L-N-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-E-I-D-F-M-R-I-L-A-T-I-I-N-F-I-I-L-I-L-I-L-K-H-F-F-W-D-K-I-K-R-A-I-D-A-R-Q-E-A-I-D-E-T-I-L-K-A-D-E-D-A-E-K-A-R-R-L-R-L-D-N-E-R-I-L-K-S-A-K-E-E-G-R-K-L-R-E-E-Q-K-K-E-A-D-R-I-Y-K-E-I-V-D-D-A-H-R-E-A-E-A-I-I-N-R-A-N-I-E-I-Q-R-E-E-E-K-V-K-Y-E-L-K-Q-Q-V-V-D-I-S-V-M-L-S-E-K-A-L-G-E-S-I-D-E-S-K-H-R-E-L-I-N-D-F-I-E-K-V-G-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-Y-E-Y-L-D-R-R-Y-A-L-A-L-Y-E-V-A-E-E-K-N-K-V-E-E-Y-L-N-D-L-R-E-I-C-D-I-I-Y-G-N-N-E-L-Y-E-I-I-K-H-P-Q-I-S-T-V-R-K-K-K-T-F-R-N-I-F-E-G-K-I-D-D-E-L-L-S-F-L-M-V-L-I-E-K-D-R-I-L-Y-L-R-E-K-L-K-E-M-E-K-I-H-L-E-R-N-N-T-L-L-A-E-V-K-S-V-V-P-L-T-E-D-E-V-T-R-L-V-A-K-L-E-N-K-Y-S-K-K-I-L-L-K-Q-E-I-D-K-S-I-I-G-G-L-Y-V-R-V-G-D-D-V-I-D-G-T-V-K-S-R-L-D-D-M-K-Q-I-M-L-K-R-E"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-N-K-F-K-L-I-V-T-T-P-E-R-V-L-I-S-G-E-V-S-R-V-L-C-K-N-A-V-G-E-F-E-I-L-A-G-H-Q-P-Y-L-T-A-T-V-P-T-V-T-R-I-D-D-E-N-G-E-S-K-Y-L-F-T-S-T-G-L-M-K-V-Q-N-N-E-V-T-F-C-V-N-S-A-E-W-P-E-E-I-D-E-A-R-A-M-N-A-K-Q-R-A-E-E-R-L-K-N-K-T-D-E-L-D-E-K-R-A-K-L-A-L-A-R-A-M-S-R-L-K-L-K-E-M"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-F-L-N-V-F-S-S-R-P-T-P-K-Q-V-A-K-D-R-L-K-V-I-L-I-H-D-R-G-E-L-S-D-E-V-L-D-K-I-R-L-E-I-L-D-V-L-S-K-Y-V-E-I-E-N-E-D-V-D-I-T-V-T-K-S-N-P-I-E-G-E-S-P-S-L-V-A-N-I-P-I-K-N-I-K-G-K-A-R"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-L-T-T-G-G-K-Q-Y-R-V-Q-E-G-D-V-L-F-V-E-K-L-N-A-E-V-D-S-T-V-E-L-T-E-V-L-A-V-A-K-D-G-E-I-K-V-G-A-P-V-V-E-G-A-K-V-V-A-K-V-L-A-Q-G-K-A-K-K-V-V-V-F-K-Y-K-R-K-K-D-Y-R-R-K-N-G-H-R-Q-P-Y-T-K-I-V-I-E-K-I-E-A"} +{"text": "### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-D-N-K-L-T-H-F-D-N-K-G-N-A-V-M-V-D-V-S-N-K-N-E-T-E-R-I-A-I-A-T-G-T-V-K-A-S-S-E-T-I-E-L-I-K-S-G-Q-I-G-K-G-D-V-L-G-V-A-R-V-A-G-I-M-A-M-K-N-T-S-N-L-I-P-M-C-H-P-V-M-I-T-G-S-S-I-D-F-E-I-D-S-E-K-N-E-I-R-I-T-A-T-S-K-V-V-H-K-T-G-V-E-M-E-A-L-T-G-V-S-I-A-A-L-T-I-Y-D-M-C-K-A-V-D-K-R-M-V-I-G-D-I-H-L-V-K-K-L-G-G-K-S-G-E-F-N-F"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-R-I-K-V-T-E-K-K-T-L-R-N-K-M-I-K-S-A-L-K-T-A-I-K-K-F-E-V-A-V-Q-A-N-N-K-A-E-A-A-T-L-Y-V-E-A-A-R-A-L-D-M-S-A-S-K-G-V-V-H-K-N-M-A-A-R-K-K-S-R-L-A-A-K-L-N-A-M-A"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-F-I-D-N-R-Q-N-K-F-D-V-T-E-E-L-T-T-K-L-E-E-V-I-S-F-V-L-K-E-E-K-V-K-E-D-C-E-V-S-L-V-F-V-D-N-E-E-I-R-G-I-N-N-E-T-R-G-I-D-K-A-T-D-V-L-S-F-P-M-I-D-Y-P-E-D-K-V-Y-K-D-V-Y-L-E-H-E-F-D-K-C-Y-F-D-G-D-E-L-I-L-G-D-I-V-L-S-L-E-R-T-K-E-Q-S-I-E-F-N-H-S-F-E-R-E-A-C-Y-L-V-T-H-S-V-L-H-L-L-G-Y-D-H-M-E-E-E-E-K-A-R-M-R-G-R-E-E-E-L-L-G-K-L-N-I-T-R-E-S"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-S-L-K-D-K-I-R-V-I-E-D-F-P-K-K-G-I-S-F-K-D-I-T-T-L-I-A-D-G-E-G-L-R-D-S-V-D-Q-M-A-E-F-F-K-D-K-N-I-D-V-V-V-G-P-E-A-R-G-F-I-F-G-V-P-V-A-Y-A-L-G-V-G-F-I-P-V-R-K-P-G-K-L-P-G-D-T-V-R-V-E-Y-D-L-E-Y-G-K-D-A-L-E-I-H-K-D-A-I-K-P-G-M-R-V-A-I-V-D-D-L-L-A-T-G-G-T-I-A-A-V-A-K-L-V-E-Q-A-G-G-E-V-A-G-L-A-F-T-I-E-L-T-E-L-K-G-R-D-K-L-K-G-Y-E-V-T-S-L-V-D-Y-D-V"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-L-S-E-V-N-K-I-S-K-N-F-A-I-N-Q-E-I-R-E-K-E-V-R-L-I-S-S-T-G-E-Q-L-G-V-V-S-G-R-D-A-Q-R-M-A-D-E-A-E-L-D-L-V-M-I-S-P-N-A-K-P-P-V-C-K-I-M-D-Y-G-K-F-I-Y-E-Q-S-K-K-E-K-E-A-K-K-K-Q-K-V-I-S-V-K-E-I-R-V-S-P-T-I-E-K-H-D-L-E-I-K-A-K-N-A-K-K-F-L-E-A-G-D-K-V-K-I-T-V-R-F-R-G-R-E-A-E-H-S-H-V-G-V-K-I-L-D-S-F-L-A-Q-L-E-E-V-C-S-V-E-K-P-A-K-L-E-G-R-N-M-I-M-I-L-A-P-K-K-A"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-A-V-N-A-R-K-N-H-K-K-V-L-K-L-A-K-G-Y-Y-G-G-K-S-K-L-F-K-T-A-N-E-S-V-I-R-A-L-R-N-A-Y-V-G-R-R-L-K-K-R-D-Y-R-R-L-W-I-A-R-I-N-A-A-T-R-M-N-G-L-S-Y-S-R-F-M-N-G-M-K-L-A-G-V-D-I-N-R-K-M-L-S-E-I-A-I-N-D-P-K-A-F-A-D-L-V-E-L-A-K-K-H-L-N-A"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-K-V-V-S-K-M-K-S-F-L-G-F-D-E-F-E-D-E-D-E-V-M-E-E-E-E-V-M-E-E-E-E-S-F-A-P-V-L-S-S-K-K-N-G-K-V-V-N-I-H-T-A-N-T-A-K-L-M-I-T-K-P-L-V-Y-D-D-A-T-E-I-C-T-A-L-K-N-R-K-I-V-V-I-N-T-T-S-L-E-L-R-T-A-Q-R-L-I-D-F-V-G-G-A-C-Y-A-L-C-G-E-L-Q-E-V-E-K-G-V-F-I-V-S-P-S-N-V-E-V-S-N-E-L-K-S-E-L-S-N-K-G-M-F-N-W-A-S-K"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-H-L-K-A-S-L-L-D-E-N-A-I-R-R-A-L-T-R-L-S-H-E-I-I-E-K-N-K-G-V-E-D-I-V-L-V-G-I-K-R-R-G-Y-P-L-A-E-R-L-S-E-F-I-E-K-F-E-G-V-K-I-P-V-A-S-V-D-I-T-L-Y-R-D-D-L-T-N-V-S-D-T-P-N-L-N-D-P-K-I-D-V-D-I-R-G-K-K-V-I-I-V-D-D-V-L-Y-T-C-R-T-A-R-A-A-I-D-A-I-M-D-Q-G-R-P-E-F-I-Q-L-A-V-L-V-D-R-G-H-K-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-K-D-E-I-I-K-V-Q-I-K-E-I-D-G-T-D-S-V-E-I-Y-E-N"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-G-S-D-L-R-K-G-T-T-F-E-L-D-G-Q-V-Y-T-V-I-D-F-L-H-V-K-P-G-K-G-A-A-F-V-R-T-K-L-R-N-V-I-M-G-G-V-T-D-R-T-F-N-P-T-D-K-L-Q-E-A-I-I-E-R-K-E-M-Q-Y-L-Y-S-D-G-E-L-Y-Y-F-M-D-Q-E-T-F-E-Q-I-P-L-N-H-E-K-V-E-D-A-I-K-F-L-K-E-N-M-N-A-V-I-K-F-Y-K-G-E-A-F-S-V-E-A-P-N-F-V-E-L-L-I-T-E-C-E-P-S-V-K-G-N-T-A-T-T-A-M-K-T-A-V-V-E-T-G-A-T-V-M-V-P-M-F-V-E-E-G-N-T-I-R-I-D-T-R-T-G-E-Y-M-E-R-V"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-N-R-V-K-S-R-E-Y-L-L-Q-L-A-Y-Q-M-E-I-T-S-E-T-A-L-E-T-F-N-S-F-M-E-N-E-D-I-S-K-D-D-L-D-L-A-Y-I-K-S-G-L-L-G-I-E-E-N-K-E-K-L-D-S-L-I-E-S-Q-L-V-K-W-K-L-N-R-I-S-K-V-N-L-S-I-L-R-I-S-T-Y-E-I-L-F-A-E-D-V-P-G-K-V-S-I-N-E-A-I-E-L-C-K-K-Y-S-D-N-K-S-V-S-F-I-N-G-V-L-D-K-V-Y-K-N-M-Q"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-R-K-E-T-N-Y-E-S-M-V-S-E-L-N-E-I-V-K-Q-L-E-N-G-D-L-T-L-E-E-S-I-K-S-Y-E-N-G-V-K-I-V-N-K-L-Y-K-K-L-S-T-L-E-G-K-I-K-V-V-E-D-E-K-E-E-D-F-G-G-Y-S-N-E-Y"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-L-G-L-D-I-G-S-K-T-I-G-V-A-V-S-D-P-L-G-W-T-A-Q-G-V-T-T-I-K-R-D-C-Y-T-K-D-V-E-A-V-M-K-I-C-K-E-Y-G-V-E-T-I-V-A-G-M-P-K-N-M-N-G-T-I-G-P-S-G-E-M-V-K-N-L-C-E-Q-I-E-K-S-F-D-G-K-I-E-F-W-D-E-R-L-T-T-V-A-A-H-R-A-M-L-E-A-D-L-S-R-A-K-R-K-K-I-V-D-K-I-A-A-T-Y-I-L-Q-G-Y-L-D-R-I-S-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-Y-C-S-Y-E-E-S-K-V-V-D-S-R-S-A-E-D-Y-N-A-I-R-R-R-R-E-C-L-R-C-S-K-R-Y-T-T-Y-E-K-V-E-D-I-P-I-L-V-I-K-K-D-L-S-R-E-S-F-N-K-E-K-I-I-S-G-L-I-K-A-C-Q-K-R-P-V-S-R-A-Q-I-E-E-I-A-A-D-I-E-R-N-I-S-N-K-M-M-V-E-I-K-S-D-Y-I-G-E-M-I-M-E-R-L-K-D-I-D-E-V-S-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-I-N-T-F-M-E-E-I-K-S-L-M-K"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-N-N-S-M-I-N-P-S-I-V-D-L-L-K-R-V-E-D-R-Y-S-L-V-I-L-S-A-K-R-A-R-Q-I-I-D-G-A-E-T-F-V-D-V-E-S-N-K-P-L-T-I-A-I-N-E-I-D-E-G-F-V-N-Y-K-D-T-E-E-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-I-R-N-L-R-F-N-D-D-E-I-L-R-K-K-C-R-V-V-D-D-I-N-D-R-I-K-V-L-V-E-D-M-I-E-T-M-Y-E-N-N-G-V-G-L-A-S-P-Q-V-G-I-L-K-R-I-F-V-V-D-A-M-D-G-A-G-S-R-V-F-I-N-P-E-I-L-E-K-S-G-E-Q-T-D-E-E-G-C-L-S-L-P-G-R-H-K-P-V-K-R-A-N-K-I-K-I-K-A-L-D-V-N-G-N-E-F-V-L-D-A-E-G-F-L-A-R-A-I-Q-H-E-Y-D-H-L-E-G-V-L-F-I-D-H-E-L"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-F-D-K-L-K-E-I-I-A-D-K-L-S-V-N-E-D-E-I-T-M-E-S-T-F-I-D-D-L-G-A-D-S-L-D-I-V-E-L-I-M-A-L-E-E-E-L-E-M-E-I-P-D-E-D-A-E-G-F-K-T-V-G-D-V-V-E-Y-I-T-E-H-T-E-K"} +{"text": "### FUNCTION A probable RNA chaperone Forms a complex with KhpB which binds to cellular RNA and controls its expression Plays a role in peptidoglycan homeostasis and cell length regulation ### SEQUENCE -M-K-E-L-V-E-I-I-A-K-S-L-V-D-K-P-E-D-V-H-V-N-E-V-L-G-E-E-S-I-I-L-E-L-K-V-S-P-E-D-M-G-K-V-I-G-K-Q-G-R-I-A-K-A-I-R-T-V-V-K-A-A-A-I-K-E-N-K-K-V-V-V-E-I-I"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-D-L-L-V-V-G-Q-I-I-N-T-H-G-L-R-G-E-M-K-V-M-P-L-T-E-D-M-R-R-F-D-Y-L-E-Y-V-I-L-K-G-K-K-V-K-V-E-G-V-K-Y-F-K-D-K-V-I-L-K-L-E-G-I-N-S-I-E-E-A-E-K-L-K-R-T-Y-L-E-I-E-R-E-D-A-I-E-L-E-E-D-E-Y-F-I-V-D-L-V-G-C-T-V-V-D-T-E-G-F-E-Y-G-K-I-K-D-V-I-Q-T-P-S-N-D-V-Y-W-V-Q-G-K-K-E-V-L-V-P-V-L-K-D-I-V-L-D-I-N-M-D-E-K-L-I-T-I-R-P-S-G-E-W-Q-Y-E-D"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-E-I-I-R-A-I-E-K-E-Q-I-R-E-D-L-T-Q-F-N-I-G-D-T-I-K-V-H-V-R-I-K-E-G-N-R-E-R-I-Q-V-F-E-G-T-V-I-K-K-Q-N-G-G-L-R-E-T-F-T-V-R-R-V-A-Y-G-V-G-V-E-R-T-F-P-I-N-A-P-I-I-D-K-I-D-V-V-R-R-G-K-V-R-R-A-K-L-F-Y-L-R-D-R-V-G-K-A-A-K-V-K-E-L-T-R"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-K-K-E-Q-L-V-A-D-L-E-A-L-C-A-P-I-V-K-E-K-G-Y-D-L-Y-H-I-E-Y-V-K-E-N-N-E-Y-Y-L-R-L-Y-I-E-K-P-E-E-R-I-S-L-R-D-C-E-I-V-S-R-A-L-S-D-M-L-D-I-E-D-P-I-K-D-A-Y-F-L-E-V-S-S-P-G-L-N-R-R-L-H-S-D-E-H-F-N-R-F-I-G-K-E-V-F-V-G-F-K-S-S-L-S-G-R-K-N-V-K-G-I-L-K-D-V-Q-E-N-E-I-I-V-E-C-E-G-N-E-I-K-V-P-K-D-K-I-K-T-A-N-L-E-G-E-I"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-N-F-R-G-K-R-I-N-E-E-V-R-K-E-V-S-D-I-I-R-N-Q-I-K-D-P-R-L-T-A-M-V-S-V-T-Q-V-E-V-T-K-D-L-R-Y-A-K-V-F-V-S-L-F-A-K-N-D-E-E-K-E-E-S-L-K-A-L-K-S-S-A-G-F-I-R-R-E-V-G-N-R-V-K-L-R-S-T-P-E-I-L-F-E-E-D-N-S-I-D-N-A-M-Y-I-E-S-L-L-N-K-I-K-E-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-D-K-I-R-K-Q-E-I-I-A-K-H-A-R-H-E-G-D-T-G-S-P-E-V-Q-I-A-L-L-T-E-R-I-N-S-L-T-D-H-L-R-T-H-K-K-D-H-H-S-R-R-G-L-L-M-M-V-G-Q-R-R-G-L-L-N-Y-L-Y-E-Q-D-I-E-R-Y-R-A-I-I-K-E-L-G-L-R-R"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-N-L-N-N-L-T-S-K-I-L-N-D-A-E-E-K-K-K-Y-I-L-A-D-A-E-A-Q-K-D-K-I-I-S-K-K-T-N-R-A-E-A-D-K-E-E-I-I-T-K-A-N-I-E-A-E-V-K-K-A-R-I-I-S-N-A-K-L-S-V-R-N-D-M-L-R-A-K-Q-D-V-I-S-K-V-F-N-E-A-I-E-K-L-Q-N-L-S-N-G-D-Y-K-Y-Y-V-I-S-T-L-D-S-L-E-L-E-G-T-E-V-I-I-I-N-E-K-D-K-D-I-F-S-N-E-F-L-E-A-L-N-K-E-L-E-S-K-G-K-K-G-S-I-T-L-N-M-E-G-K-F-N-G-G-F-I-L-D-R-N-G-I-Q-I-N-N-T-F-E-A-L-I-N-S-L-R-G-E-L-E-F-E-V-N-K-V-L-F-D"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-D-M-Y-K-K-I-G-V-V-G-D-K-D-S-V-L-A-F-K-A-L-G-I-D-V-F-P-V-V-E-D-E-E-A-R-K-T-I-D-K-L-A-M-T-G-Y-A-V-I-F-V-T-E-H-V-A-K-N-I-E-E-T-I-E-R-Y-T-R-Q-V-L-P-A-V-I-L-I-P-S-N-Q-G-T-L-N-I-G-K-Q-R-I-S-D-N-V-E-K-A-V-G-V-N-I-L"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-V-K-K-I-V-Q-I-G-H-E-A-L-K-K-V-S-E-P-V-K-D-V-N-E-V-K-G-L-I-Q-D-L-K-D-T-L-A-T-V-E-G-I-G-L-A-A-P-Q-I-A-V-N-K-R-V-V-Y-I-N-F-G-D-G-E-N-E-Y-V-L-I-N-P-E-V-T-G-V-S-K-E-T-Y-E-D-Y-E-G-C-L-S-Y-V-M-H-E-G-L-V-E-R-P-R-A-V-R-I-Q-A-L-N-E-K-G-E-L-K-V-Y-E-A-Q-D-L-L-A-R-C-F-L-H-E-I-D-H-L-E-G-I-M-Y-V-D-R-A-K-E-M-Y-E-L-V-E-K"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-N-L-V-P-M-V-V-E-Q-T-S-K-G-E-R-S-Y-D-I-F-S-R-L-L-K-D-R-I-I-M-L-S-G-E-V-N-D-V-T-A-N-L-V-V-A-Q-L-L-F-L-E-S-E-D-P-D-K-D-I-H-L-Y-I-N-S-P-G-G-S-I-T-S-G-M-A-I-Y-D-T-M-Q-Y-I-K-P-D-V-S-T-I-C-I-G-M-A-A-S-M-G-A-F-L-L-S-S-G-A-K-G-K-R-F-A-L-P-N-A-E-I-M-I-H-Q-P-L-G-G-F-Q-G-Q-A-T-D-I-D-I-H-A-K-R-I-L-K-I-K-D-K-L-N-Q-I-L-S-E-N-T-N-Q-P-L-E-K-I-K-V-D-V-E-R-D-Y-F-M-E-A-S-E-A-V-E-Y-G-L-I-D-K-V-I-E-R-K"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-K-I-K-S-S-E-F-I-I-S-A-V-K-R-E-Q-Y-P-D-D-N-L-P-E-I-A-F-V-G-R-S-N-V-G-K-S-S-I-I-N-S-L-T-N-R-R-G-L-A-K-V-S-Q-T-P-G-K-T-R-L-I-N-F-F-L-L-N-K-D-F-Y-L-V-D-L-P-G-Y-G-Y-A-K-V-S-K-K-E-K-A-S-W-G-A-T-I-E-R-Y-L-L-N-R-G-P-L-K-K-V-V-L-L-V-D-C-R-H-K-P-T-A-D-D-V-Q-M-Y-E-W-I-K-H-Y-G-Y-E-V-V-V-I-A-T-K-S-D-K-I-S-N-N-Q-I-G-K-S-E-K-L-I-K-E-T-L-G-L-P-K-D-H-K-L-K-F-F-S-S-L-N-K-K-G-K-D-E-L-V-D-Y-L-F-D-D-L-V-E-E-V"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-R-K-D-N-K-T-L-A-E-N-R-K-A-R-H-D-Y-F-V-D-E-A-M-E-A-G-I-A-L-V-G-T-E-V-K-S-I-R-N-G-R-V-N-L-K-D-C-Y-A-D-I-N-N-G-E-I-F-I-N-N-M-H-I-S-P-Y-E-Q-G-N-I-F-N-V-D-P-L-R-K-R-K-L-L-L-H-K-S-E-I-Q-R-L-I-G-I-V-Q-Q-Q-G-V-A-L-I-P-L-S-L-Y-L-K-N-G-R-V-K-V-N-L-G-V-C-R-G-K-K-N-Y-D-K-R-D-T-M-L-E-K-A-H-K-R-E-M-D-R-Q-L-K-E-R-N-R-Y"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-N-K-S-I-N-N-L-Q-D-I-F-L-N-N-A-R-K-E-R-I-P-V-T-I-F-L-V-N-G-V-Q-L-K-G-I-V-K-G-F-D-S-F-T-V-V-L-D-S-D-G-K-Q-Q-L-V-Y-K-H-A-I-S-T-V-S-P-A-K-P-I-L-F-N-N-A-Q-V-F-D-N"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-E-I-K-K-P-A-L-A-G-T-L-E-S-S-D-C-I-V-S-V-E-P-S-M-D-N-T-I-E-I-N-L-T-S-T-V-K-K-Q-F-G-N-E-I-I-K-V-A-K-E-T-L-K-N-L-G-V-N-S-V-V-M-E-I-N-D-K-G-A-L-N-C-V-I-E-A-R-I-E-A-A-V-C-R-A-S-E-I-N-E-F-D-W-G-N-Y-K-C-Q-D"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-M-N-I-N-E-I-K-E-I-L-P-H-K-Y-P-F-L-L-V-D-K-V-E-E-I-T-E-S-K-V-V-A-Y-K-N-V-T-I-N-E-P-F-F-Q-G-H-F-P-D-Y-P-V-M-P-G-V-L-I-V-E-A-L-A-Q-A-G-A-I-A-L-L-N-K-E-E-F-K-G-K-T-P-F-F-A-G-I-D-K-V-R-F-K-K-Q-V-L-P-G-D-T-L-R-L-E-V-E-I-I-K-L-R-G-S-I-G-F-G-K-A-T-A-T-V-D-G-K-I-A-C-S-G-E-I-M-F-A-I-G"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Q-K-L-L-L-A-L-I-V-G-L-G-G-F-L-G-A-S-L-R-Y-L-I-S-I-F-A-A-K-N-F-G-G-N-F-P-Y-G-T-L-I-A-N-I-L-G-A-L-L-I-G-F-I-M-E-F-S-M-D-S-A-L-I-S-S-N-M-K-L-F-L-T-T-G-I-M-G-G-L-T-T-F-S-T-F-S-Y-E-T-I-S-M-L-T-N-G-N-M-T-L-G-I-E-N-I-I-L-N-L-G-C-S-L-L-F-V-V-I-G-Q-K-L-A-R-I-L-F"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-K-I-A-L-I-A-H-D-K-K-K-E-E-M-I-E-L-A-K-D-F-E-D-K-L-S-K-H-I-L-V-A-T-G-T-T-G-L-K-I-M-Q-N-T-S-L-E-V-K-R-C-K-S-G-P-L-G-G-D-Q-E-I-G-A-M-V-A-N-H-D-V-D-M-V-I-F-L-R-D-P-L-T-A-Q-P-H-E-P-D-I-S-A-L-L-R-L-C-D-V-Y-K-V-P-L-A-T-N-T-E-S-A-K-L-I-M-A-D-I"} +{"text": "### FUNCTION May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor ### SEQUENCE -M-R-K-F-L-K-S-A-I-E-Y-L-A-K-D-L-D-L-D-K-E-L-L-E-Q-I-Q-Y-V-V-I-V-L-T-F-E-F-I-K-C-I-S-V-I-L-I-A-G-I-L-G-Y-F-K-E-S-L-I-V-I-L-S-M-C-F-I-K-P-F-I-G-G-Y-H-E-D-S-Q-L-K-C-F-I-A-T-L-I-I-T-T-S-I-I-M-L-V-T-F-N-K-L-N-L-F-S-I-V-I-L-N-L-F-S-I-F-S-I-Y-N-K-A-P-V-I-D-S-R-F-P-L-T-K-E-H-L-I-K-K-N-K-I-L-S-V-T-N-S-S-I-L-F-L-I-T-L-I-F-F-K-I-S-W-I-S-Q-T-I-T-W-T-L-L-I-Q-T-L-L-L-F-N-K-Y-K-R-E-D-S"} +{"text": "### FUNCTION Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule ### SEQUENCE -M-E-K-F-V-C-D-V-C-G-Y-I-Y-D-P-V-V-G-D-P-D-N-G-V-A-P-G-T-K-F-K-D-I-P-D-T-W-V-C-P-L-C-K-L-D-K-T-H-F-S-K-V-E"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-R-I-L-E-G-N-L-I-G-Q-D-K-K-F-A-I-V-A-G-R-F-N-E-F-I-V-S-K-L-I-G-G-A-L-D-A-F-K-R-H-G-V-E-E-E-N-I-D-L-A-W-V-P-G-A-F-E-I-P-L-I-A-K-K-L-A-K-S-G-K-Y-A-G-V-V-C-L-G-T-V-I-R-G-A-T-S-H-Y-D-Y-V-C-G-E-V-S-K-G-I-A-N-V-S-L-D-T-E-V-P-V-I-F-G-I-V-T-T-E-N-I-E-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-F-D-A-A-M-A-A-I-E-M-A-N-L-L-E-N-I"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-I-G-I-G-V-D-I-I-E-I-E-R-V-R-Q-A-I-Q-N-N-K-N-F-L-S-K-L-F-T-E-R-E-L-D-Y-F-I-S-R-N-M-N-S-E-V-I-A-G-N-F-A-A-K-E-A-V-S-K-A-L-G-T-G-I-R-G-F-S-F-K-D-I-E-I-L-R-N-E-L-G-K-P-E-V-I-L-H-N-G-A-N-L-I-G-N-K-L-V-G-N-N-N-S-L-R-V-H-L-S-I-S-H-N-N-S-S-A-I-A-Y-S-V-L-E-G-E-Y-Y-G-N-M"} +{"text": "### FUNCTION Part of the energy-coupling factor transporter complex CbiMNOQ involved in cobalt import ### SEQUENCE -M-K-N-K-R-V-L-T-N-V-I-L-L-L-L-V-V-F-I-T-I-I-P-F-F-V-A-K-N-G-E-F-G-G-S-D-D-Q-A-E-E-A-I-T-Q-I-D-E-N-Y-E-P-W-F-S-P-L-F-E-P-A-S-G-E-I-E-S-L-L-F-A-L-Q-A-A-I-G-A-G-V-I-G-F-G-L-G-Y-L-K-G-K-K-K-V-N-D-E-V-N-D-K-H-R"} +{"text": "### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate May function as an ADP-ribosylase ### SEQUENCE -M-K-N-N-D-S-K-I-S-K-Y-I-S-L-I-L-R-H-K-P-E-E-I-G-L-K-L-D-E-H-G-Y-L-G-V-L-D-L-I-E-G-L-N-K-S-Y-K-G-F-S-M-D-D-L-E-R-I-V-R-E-D-S-K-G-R-Y-S-F-N-E-D-K-S-K-I-R-A-N-Q-G-H-S-I-K-V-D-L-G-L-E-A-I-K-P-P-K-V-L-Y-H-G-T-G-R-K-Y-I-E-S-I-L-K-N-G-L-I-K-K-E-R-Q-Y-V-H-L-S-K-D-I-E-T-A-S-I-V-G-K-R-H-G-D-L-V-I-L-E-V-D-S-E-S-M-F-K-D-G-I-K-F-Y-L-S-K-N-N-V-W-L-C-D-Y-V-K-V-E-Y-I-K-E-I-S-L-L"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-E-F-Y-P-V-A-I-E-K-L-I-E-E-F-A-K-L-P-S-I-G-K-K-S-A-Q-R-L-T-L-H-I-L-N-L-P-K-D-E-V-E-E-F-A-N-A-L-V-K-A-R-G-T-I-K-Y-C-S-V-C-G-N-F-T-D-T-D-P-C-A-I-C-S-N-P-N-R-E-K-D-I-I-C-V-V-E-Q-P-K-D-I-M-T-M-E-K-V-K-E-F-N-G-L-Y-H-V-L-H-G-T-I-S-P-M-Q-G-R-G-P-Q-D-I-R-I-R-E-L-V-A-R-M-S-G-D-V-K-E-V-I-V-A-T-N-P-T-I-E-G-E-A-T-A-M-Y-I-S-K-I-L-K-P-L-D-V-K-V-T-R-I-A-A-G-I-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-L-E-G-R-T-V-I"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-R-G-G-F-P-G-G-M-G-N-M-N-N-L-M-K-Q-A-Q-M-L-Q-K-Q-M-Q-S-M-Q-E-E-I-E-A-S-E-F-E-G-S-A-G-G-G-A-V-V-A-K-V-N-G-K-K-E-L-I-A-L-N-I-K-P-E-V-V-D-P-D-D-V-E-M-L-E-D-L-V-F-S-A-V-K-Q-A-L-E-K-A-S-E-E-T-S-E-K-M-G-K-L-T-G-G-M-G-M-P-G-L-F"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-N-P-T-V-L-D-Q-I-R-H-I-I-A-Q-A-L-D-K-P-V-E-T-I-H-A-E-Q-S-F-R-R-D-L-G-A-D-S-L-D-S-V-E-I-V-M-A-I-E-D-Q-F-A-V-E-F-D-E-D-S-T-A-A-V-D-T-V-Q-D-L-V-T-Y-I-E-A-A-L-A-S-R-G-A-Q-T-A"} +{"text": "### FUNCTION Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-D-T-Q-D-I-V-S-E-I-S-E-L-N-L-T-Y-L-M-L-A-Q-Q-M-L-A-K-D-R-D-A-A-L-F-R-L-G-I-S-E-E-L-A-D-I-L-L-T-M-S-P-A-Q-I-V-K-L-A-S-T-N-M-L-L-C-R-F-R-F-D-D-H-A-I-L-G-L-V-T-Q-P-H-R-D-K-G-L-Q-Q-S-Q-M-S-I-L-L-A-R-Q-A-V-E-Q-I-N"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-P-L-L-T-V-D-V-V-T-A-E-E-R-L-Y-Q-G-T-A-K-F-V-V-V-P-G-T-E-G-E-L-G-I-L-P-G-H-E-P-L-L-T-R-L-R-P-G-T-V-R-V-T-L-E-N-D-D-E-V-I-L-F-V-A-G-G-F-A-H-I-L-P-Q-E-V-I-L-L-A-D-T-A-V-R-A-R-D-L-D-E-A-K-A-Q-Q-A-R-K-A-A-E-E-L-L-Q-N-S-R-S-K-I-D-Y-A-R-A-Q-A-E-L-A-E-A-V-A-Q-L-A-A-I-E-R-A-R-R-R-R-R"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-T-E-T-E-I-L-E-R-I-R-S-I-F-Q-E-N-F-A-I-D-P-A-R-V-T-P-E-A-H-L-F-E-E-L-D-L-D-S-I-D-A-V-D-L-A-I-K-L-Q-E-M-T-G-R-R-I-K-P-E-E-F-K-S-V-R-T-V-G-D-V-I-G-A-V-Q-S-L-L-A-A"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-I-L-S-F-L-L-G-E-K-K-K-T-A-S-V-A-K-E-R-L-Q-I-I-L-A-H-E-R-S-S-H-S-A-P-A-D-Y-L-P-A-L-Q-R-E-L-V-A-V-I-S-K-Y-V-K-I-G-N-D-D-I-K-V-N-L-E-R-Q-D-N-L-E-V-L-E-V-K-I-E-I-P-Q-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-L-N-A-T-L-V-A-Q-M-V-V-F-F-I-L-W-W-V-V-A-K-F-I-W-P-P-L-V-K-A-L-D-E-R-A-K-K-I-A-D-G-L-A-A-A-D-K-G-K-A-E-L-E-L-A-N-K-R-V-E-Q-A-L-T-E-A-R-T-E-G-A-Q-R-I-A-D-A-E-K-R-A-Q-M-T-A-D-E-I-K-Q-N-A-Q-A-E-A-A-R-I-V-A-Q-A-K-A-E-A-E-Q-Q-A-V-R-V-R-E-S-L-R-D-Q-V-A-V-L-A-V-K-G-A-E-Q-I-L-K-R-E-V-N-A-Q-V-H-A-D-L-L-T-Q-L-K-A-E-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-L-A-T-V-A-R-P-Y-A-E-A-L-F-R-V-A-K-A-G-N-L-G-A-W-S-E-L-V-S-E-M-G-Q-I-A-A-V-P-D-M-K-A-V-A-D-D-P-K-L-S-K-A-D-V-A-G-I-F-L-S-A-L-K-S-P-V-S-H-E-A-K-E-L-V-G-L-L-V-A-N-K-R-L-S-L-L-P-E-I-A-A-Q-F-H-V-L-R-N-A-S-E-G-A-A-D-V-E-I-T-S-A-F-P-L-E-G-A-P-L-T-D-L-V-A-T-L-E-R-K-F-G-K-K-L-Q-P-H-V-T-V-D-P-S-L-I-G-G-V-R-V-Q-V-G-D-E-V-L-D-T-S-V-R-A-R-L-A-Q-M-Q-S-A-L-T-A-A"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-T-I-H-V-D-V-V-S-A-E-Q-E-I-F-S-G-D-A-K-F-V-A-L-P-G-E-A-G-E-L-G-I-L-P-G-H-T-P-L-I-T-R-I-K-P-G-A-V-R-I-E-T-E-A-G-E-E-F-V-F-V-A-G-G-I-L-E-V-Q-P-K-H-V-T-V-L-A-D-T-A-I-R-G-H-D-L-D-E-A-K-A-N-E-A-K-R-A-A-E-E-A-L-Q-N-Q-S-S-D-L-D-L-A-R-A-Q-G-E-L-A-V-A-T-A-Q-L-A-A-I-A-R-L-R-R-K-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-T-P-V-E-L-K-Y-T-E-S-H-E-W-V-R-T-E-A-D-G-T-L-T-I-G-I-T-D-L-A-Q-E-Q-L-G-D-I-V-F-L-E-L-P-D-T-G-R-Q-V-K-Q-G-E-A-I-A-V-V-E-S-V-K-A-A-S-D-I-Y-A-P-V-S-G-E-V-I-A-S-N-A-D-A-T-E-S-P-E-S-V-N-E-D-A-Y-D-A-W-L-F-K-I-K-P-A-N-A-D-D-V-N-A-L-L-S-A-D-Q-Y-Q-A-K-A-G-A"} +{"text": "### FUNCTION Specific class of high-redox-potential 4Fe-4S ferredoxins Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus of halophilic, denitrifying bacteria ### SEQUENCE -M-S-N-R-R-L-F-L-K-S-I-P-I-M-A-A-A-G-A-V-G-M-A-G-L-A-R-A-A-N-P-M-V-A-E-T-D-P-Q-A-A-A-L-G-Y-K-A-D-T-T-K-V-D-Q-A-K-Y-P-K-H-A-P-D-Q-H-C-G-N-C-A-L-Y-Q-G-G-T-A-A-Q-G-G-C-P-L-F-A-G-K-D-V-A-N-K-G-W-C-S-A-W-A-K-K-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-I-G-F-I-K-L-Q-I-P-A-G-K-A-N-P-S-P-P-V-G-P-A-L-G-Q-R-G-L-N-I-M-E-F-C-K-A-F-N-A-Q-T-Q-G-M-E-P-G-L-P-V-P-V-V-I-T-A-F-A-D-K-S-F-T-F-V-M-K-S-P-P-A-T-V-L-I-K-K-A-A-G-V-Q-K-G-S-A-K-P-H-T-D-K-V-G-K-I-T-R-A-Q-A-E-E-I-A-K-A-K-N-A-D-L-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-I-T-V-E-G-L"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-E-D-K-K-A-V-V-A-E-V-T-A-Q-V-A-K-A-S-T-I-V-V-A-E-Y-R-G-I-T-V-G-D-L-T-K-L-R-A-Q-A-R-Q-Q-G-V-Y-L-R-V-L-K-N-T-L-A-R-R-A-V-E-G-T-P-F-A-E-L-A-E-Q-M-T-G-P-L-I-Y-G-I-S-E-D-A-V-A-P-A-K-V-L-N-D-F-A-K-G-N-D-K-L-V-L-R-A-G-S-Y-E-G-K-V-L-D-A-A-G-V-K-A-L-A-S-I-P-S-R-E-E-L-L-S-K-L-L-F-V-M-Q-A-P-V-S-G-F-A-R-A-L-A-A-L-A-E-K-K-Q-S-E-E-G-A-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-I-T-K-D-D-I-L-E-A-V-S-A-M-S-V-M-E-L-N-D-L-V-K-A-F-E-D-K-F-G-V-S-A-A-A-V-A-V-A-G-P-A-G-G-A-A-A-P-A-A-E-E-K-T-E-F-D-V-I-L-K-G-A-G-A-N-K-V-G-V-I-K-A-V-R-E-I-T-G-L-G-L-K-E-A-K-D-L-V-D-G-A-P-K-T-V-K-E-A-M-P-K-A-D-A-D-A-A-A-K-K-L-I-E-A-G-A-E-V-E-V-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-K-P-R-V-S-E-K-L-K-S-K-S-P-A-L-E-N-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-V-R-L-T-N-G-F-E-V-I-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-S-L-D-L-Q-G-V-K-D-R-K-Q-A-R-S-K-Y-G-A-K-R-P-K-A-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-E-V-P-K-R-E-I-L-P-D-P-K-F-G-N-V-E-V-A-K-F-M-N-V-L-M-L-D-G-K-K-S-V-A-E-R-I-V-Y-G-A-F-D-Q-I-E-K-K-A-G-K-A-P-I-E-V-F-T-L-A-I-G-N-I-K-P-V-V-E-V-K-S-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-R-P-S-R-R-L-A-L-A-M-R-W-L-R-E-A-A-K-K-R-S-E-K-S-M-A-L-R-L-A-G-E-L-L-E-A-S-E-G-R-G-G-A-M-K-K-R-D-E-V-H-R-M-A-E-A-N-K-A-F-S-H-F-R-F"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-Q-N-Q-K-I-R-I-R-L-K-A-F-D-Y-R-L-I-D-Q-S-A-A-E-I-V-E-T-A-K-R-T-G-A-I-V-K-G-P-V-P-L-P-T-R-I-Q-R-F-D-V-L-R-S-P-H-V-N-K-T-S-R-D-Q-F-E-I-R-T-H-Q-R-L-M-D-I-V-D-P-T-D-K-T-V-D-A-L-M-K-L-D-L-P-A-G-V-D-V-E-I-K-L-Q"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-Q-V-A-K-N-D-H-R-L-M-Q-V-L-L-S-P-V-V-S-E-K-A-T-L-V-A-D-K-N-E-Q-V-V-F-E-V-A-R-D-A-N-K-G-E-V-K-A-A-V-E-L-L-F-K-V-E-V-E-S-V-Q-I-L-N-Q-K-G-K-Q-K-R-F-G-R-F-M-G-R-R-D-H-V-K-K-A-Y-V-S-L-K-P-G-Q-E-I-N-F-E-A-E-A-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-A-K-K-G-P-F-I-D-A-H-L-L-K-K-V-E-A-A-A-G-G-K-D-K-K-P-I-K-T-W-S-R-R-S-T-I-L-P-D-F-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-Y-V-T-E-N-M-V-G-H-K-L-G-E-F-A-L-T-R-T-F-K-G-H-A-A-D-K-K-A-K-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-V-K-A-I-H-R-G-A-R-I-S-A-Q-K-T-R-L-V-A-D-Q-I-R-G-L-P-I-E-R-A-L-N-V-L-A-F-S-P-K-K-A-A-V-I-V-K-K-V-V-E-S-A-I-A-N-A-E-H-N-E-G-A-D-I-D-E-L-K-V-K-S-I-Y-I-D-K-A-T-S-L-K-R-F-T-A-R-A-K-G-R-G-N-R-I-E-K-Q-T-C-H-I-T-V-T-L-G-N"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-R-K-Y-R-K-E-Q-K-G-R-N-T-G-I-A-T-R-G-N-A-V-S-F-G-E-F-G-L-K-A-M-G-R-G-R-L-T-A-R-Q-I-E-S-A-R-R-A-M-T-R-H-I-K-R-G-G-R-I-W-I-R-I-F-P-D-K-P-I-S-K-K-P-A-E-V-R-M-G-N-G-K-G-N-P-E-Y-Y-V-A-E-I-Q-P-G-K-M-L-Y-E-M-D-G-V-G-E-E-L-A-R-E-A-F-R-L-A-A-A-K-L-P-I-A-T-S-F-V-V-R-Q-V-G-T"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-T-E-A-A-T-S-L-K-R-T-L-V-G-R-V-V-S-S-K-M-D-K-T-V-T-V-L-V-E-N-R-V-K-H-P-L-Y-G-K-Y-V-V-R-S-K-K-Y-H-A-H-D-E-A-N-Q-Y-K-E-G-D-R-V-E-I-V-E-S-R-P-I-S-R-T-K-A-W-V-V-S-R-L-V-E-A-A-R-V-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-T-E-S-R-L-E-V-A-D-N-T-G-A-R-E-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-S-V-G-D-I-I-K-V-S-V-K-D-A-A-P-R-G-R-V-K-K-G-D-I-Y-N-A-V-V-V-R-T-A-K-G-V-R-R-P-D-G-S-L-I-K-F-D-G-N-A-A-V-L-L-N-T-K-L-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-R-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-N-K-I-R-K-G-D-R-V-I-V-R-T-G-K-D-K-G-K-Q-G-T-V-L-A-V-L-G-E-H-V-T-V-E-G-V-N-V-A-K-K-H-V-R-P-N-P-M-L-G-T-T-G-G-V-V-D-K-V-M-P-I-H-I-S-N-V-A-L-V-D-A-N-G-K-P-S-R-V-G-I-K-V-E-N-G-V-K-T-R-V-L-K-T-T-G-A-A-V-G-A"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-A-R-L-Q-E-F-Y-K-E-K-V-V-A-E-L-I-K-Q-F-G-Y-K-S-V-M-E-V-P-R-I-T-K-I-T-L-N-M-G-L-G-E-A-V-N-D-K-K-V-I-E-H-A-T-G-D-L-T-K-I-A-G-Q-K-P-V-V-T-K-A-R-K-A-I-A-G-F-K-I-R-Q-G-Y-P-I-G-T-M-V-T-L-R-G-Q-R-M-Y-E-F-L-D-R-F-I-T-V-S-L-P-R-V-R-D-F-R-G-V-S-G-R-A-F-D-G-R-G-N-Y-N-I-G-V-K-E-Q-I-I-F-P-E-I-E-Y-D-K-I-D-A-L-R-G-L-N-I-S-I-T-T-T-A-K-S-D-E-E-A-K-A-L-L-A-A-F-K-F-P-F-R-N"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-L-S-L-I-E-R-E-K-K-R-A-K-L-V-A-K-Y-A-E-K-R-A-A-L-E-A-I-V-A-D-Q-S-K-S-E-E-E-R-Y-E-A-R-L-K-L-Q-Q-L-P-R-N-A-N-P-T-R-Q-R-N-R-C-S-I-T-G-R-P-R-G-T-F-R-K-F-G-L-A-R-N-K-L-R-E-I-A-F-K-G-E-I-P-G-L-T-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-S-D-P-I-A-D-M-L-T-R-I-R-N-A-Q-A-V-E-K-A-S-V-V-M-P-S-S-K-L-K-V-A-I-A-K-V-L-K-D-E-G-Y-I-D-D-F-A-V-T-E-Q-G-G-K-A-S-L-T-I-G-L-K-Y-Y-A-G-R-P-V-I-E-R-L-E-R-V-S-K-P-G-L-R-V-Y-K-G-R-N-E-I-P-Q-V-M-N-G-L-G-V-A-I-I-S-T-P-Q-G-L-M-T-D-R-R-A-R-A-T-G-V-G-G-E-V-I-C-Y-V-A"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-A-P-I-A-L-P-K-G-A-E-V-N-F-A-G-G-L-L-T-V-K-G-P-L-G-T-L-T-Q-A-I-H-N-L-V-K-V-V-I-D-N-G-T-I-T-F-S-P-A-D-E-S-R-E-A-N-A-L-Q-G-T-M-R-A-L-V-A-N-M-V-K-G-V-T-T-G-F-E-R-K-L-T-L-V-G-V-G-Y-R-A-S-L-Q-G-A-A-L-K-L-Q-L-G-F-S-H-D-V-I-H-E-M-P-E-G-V-K-A-E-T-P-T-Q-T-E-I-I-I-K-G-S-D-K-Q-K-V-G-Q-V-A-A-E-V-R-G-Y-R-P-P-E-P-Y-K-G-K-G-V-R-Y-A-N-E-R-V-I-L-K-E-T-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-N-K-N-D-S-R-L-R-R-A-R-Q-T-R-L-K-I-A-E-L-N-V-A-R-L-A-V-H-R-T-N-L-H-I-Y-A-Q-V-F-S-E-D-G-T-K-V-L-A-S-A-S-T-A-E-A-E-V-R-K-E-L-N-G-N-G-G-N-T-A-A-A-T-L-V-G-K-R-I-A-E-K-A-K-A-A-G-I-E-A-V-A-F-D-R-S-G-F-R-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-A-G-L-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-K-I-Q-P-K-V-Q-G-D-E-R-D-D-G-L-R-E-K-M-I-A-V-N-R-V-T-K-V-V-K-G-G-R-I-L-G-F-A-A-L-T-V-V-G-D-G-D-G-R-I-G-M-G-K-G-K-A-K-E-V-P-V-A-V-Q-K-A-M-D-E-A-R-R-K-M-V-K-V-P-L-K-N-G-T-L-Q-H-E-V-I-G-K-H-G-A-A-K-V-L-M-A-P-A-K-E-G-T-G-V-I-A-G-G-P-M-R-A-I-F-E-V-M-G-V-T-N-I-V-T-K-S-H-G-S-T-N-P-Y-N-M-V-R-A-T-L-D-G-L-R-K-M-S-T-P-A-E-I-A-A-K-R-G-K-S-V-E-E-I-L-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-L-N-N-L-K-P-A-A-G-S-K-H-A-K-R-R-V-G-R-G-I-G-S-G-L-G-K-T-A-G-R-G-H-K-G-Q-K-S-R-S-G-G-F-H-K-V-G-F-E-G-G-Q-M-P-L-H-R-R-L-P-K-R-G-F-T-S-L-T-K-E-F-T-A-E-V-R-L-G-D-L-A-G-L-P-V-A-E-I-D-L-L-T-L-K-Q-A-G-L-V-G-E-L-V-K-S-A-K-V-I-L-S-G-S-I-D-K-K-V-T-L-K-G-L-G-A-T-A-G-A-K-A-A-I-E-A-A-G-G-S-L-A"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-Q-M-Q-G-E-V-Q-E-N-L-P-N-A-T-F-R-V-K-L-E-N-G-H-V-V-L-G-H-I-S-G-K-M-R-M-H-Y-I-R-I-L-P-G-D-K-V-T-V-E-L-T-P-Y-D-L-S-R-A-R-I-V-F-R-A-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-N-H-K-H-T-V-I-G-L-T-A-I-Y-G-I-G-R-S-R-A-R-K-I-C-E-A-T-G-I-P-T-D-K-K-V-K-D-L-T-D-P-D-Q-D-A-L-R-K-E-I-E-K-F-L-V-E-G-D-L-R-R-E-T-T-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-V-R-H-R-K-G-L-P-L-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-K-A-G-V-A-L-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-A-A-N-T-A-A-Q-R-A-R-K-K-V-R-K-N-V-A-D-G-I-A-H-V-H-A-S-F-N-N-T-I-I-T-I-T-D-R-Q-G-N-A-L-S-W-A-T-S-G-G-Q-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-S-A-G-R-V-A-Q-D-Q-G-I-K-N-L-E-V-R-I-K-G-P-G-P-G-R-E-S-A-V-R-A-L-N-N-L-G-I-K-I-Q-V-I-E-D-V-T-P-V-P-H-N-G-C-R-P-P-K-R-R-R-I"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-P-P-L-T-E-S-E-F-L-A-L-A-D-A-E-L-G-R-I-E-R-T-V-E-R-A-A-D-E-V-D-A-D-I-E-I-G-R-V-G-N-V-L-T-L-E-F-D-D-G-S-K-I-I-I-N-S-Q-T-P-M-Q-E-L-W-V-A-A-R-A-G-G-F-H-F-R-R-N-D-G-R-W-V-D-T-R-S-G-E-E-L-Y-V-A-L-S-R-Y-V-S-Q-Q-S-E-V-D-V-T-L-V-A-D"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-I-W-H-W-L-I-V-L-L-I-I-M-M-V-F-G-T-K-K-L-R-N-I-G-S-D-L-G-S-A-V-K-G-F-K-E-G-M-R-E-G-S-E-D-K-P-A-G-S-Q-Q-G-Q-Q-A-A-G-Q-P-P-R-E-L-H-D-S-T-T-I-D-V-E-A-R-D-K-S-K-Q-G"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-I-D-L-G-I-S-K-L-A-L-I-G-A-V-A-L-V-V-I-G-P-E-R-L-P-K-V-A-R-T-A-G-A-L-I-G-R-A-Q-R-Y-I-A-D-V-K-A-E-V-S-R-E-I-E-L-E-E-L-R-K-M-R-T-E-F-E-E-A-A-R-N-V-E-Q-T-I-H-Q-E-V-S-R-H-T-S-E-I-N-E-R-L-N-E-A-L-G-D-P-A-S-R-Q-T-A-T-Q-A-A-E-W-R-P-A-P-A-K-S-R-N-G-R-N-S-W-R-N-K-Q-L-A-M-P-K-W-Y-R-R-K-Q-G-V-R-M-W-A-Q-S-G-A-A-R-V-K-R-H-R-P-P-I-V-A-A-Q-S-R-G-R-S-F-F-E"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-A-L-M-Q-D-F-K-K-F-A-M-R-G-N-V-I-D-L-A-V-G-V-I-I-G-A-A-F-G-K-I-V-D-S-L-V-N-D-L-I-M-P-L-V-A-R-I-V-G-K-L-D-F-S-N-L-F-I-Q-L-A-D-A-P-A-G-V-P-Q-T-L-A-D-L-K-K-A-G-V-P-V-F-A-Y-G-N-F-I-T-V-A-V-N-F-L-I-L-A-F-I-V-F-L-M-V-R-A-I-T-R-V-I-D-T-N-P-P-P-A-D-T-P-E-N-T-L-L-L-R-D-I-R-D-S-L-K-S-K-N-Q"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-N-M-K-T-V-K-C-P-T-C-G-K-P-V-P-W-T-P-E-S-R-Y-R-P-F-C-S-E-R-C-K-Q-I-D-L-G-A-W-A-A-E-Q-Y-T-I-P-V-V-E-D-D-D-L-P-P-D-A-P-G-G-E-S-G-G-A-S-G-R-L-N"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-V-K-T-G-G-K-Q-Y-K-V-A-A-G-E-K-L-K-V-E-Q-I-P-A-D-V-G-A-E-I-T-L-D-Q-V-L-A-V-G-A-G-D-Q-L-K-V-G-A-P-L-V-S-G-A-A-V-K-A-T-V-I-S-H-G-R-H-D-K-V-K-I-F-K-M-R-R-R-K-H-Y-Q-K-H-Q-G-H-R-Q-N-Y-T-E-L-R-I-D-S-I-V-A"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-S-G-A-A-M-S-Y-P-R-S-P-W-R-G-A-L-P-P-M-A-V-Y-G-Q-H-W-A-R-W-A-V-G-V-N-S-L-T-A-R-L-R-A-A-S-S-S-F-R-V-E-L-L-G-Q-G-R-A-L-P-L-R-D-E-W-R-C-L-G-L-P-R-A-A-E-T-L-A-R-E-V-L-L-I-C-D-E-A-P-V-V-Y-A-H-T-I-V-H-P-R-S-V-A-A-D-W-P-F-L-R-A-L-G-T-Q-P-L-G-H-A-L-F-A-D-P-R-V-A-R-G-A-F-E-F-A-L-L-D-G-R-H-P-L-V-K-R-A-H-A-A-L-G-G-T-P-P-G-A-M-A-R-L-P-A-R-R-S-V-F-R-R-G-V-S-A-M-L-V-T-E-V-F-L-P-A-L-A-V-F-D-P-P-P-M-M"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-A-Q-A-R-K-R-A-R-Q-A-V-V-Q-N-A-H-N-S-A-L-R-S-R-L-R-T-A-V-K-A-V-R-K-A-I-A-G-G-D-K-A-A-A-A-N-V-F-K-Q-A-Q-S-T-I-D-S-I-A-D-K-K-I-V-H-K-N-K-A-A-R-A-K-S-R-L-S-A-A-I-K-A-M-G-A"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-A-I-R-Q-A-T-T-P-Q-H-D-A-G-T-V-L-E-R-K-E-Q-A-L-K-P-P-A-M-Y-K-V-L-L-L-N-D-D-Y-T-P-M-E-F-V-V-M-I-L-Q-Q-Y-F-S-K-D-R-E-T-A-T-Q-I-M-L-T-V-H-R-E-G-R-G-V-C-G-I-Y-T-R-D-I-A-A-T-K-V-E-L-V-S-T-H-A-R-Q-A-G-H-P-L-Q-C-V-M-E-E-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-L-D-V-Q-I-L-D-A-R-L-H-E-Q-L-P-Q-Y-A-T-P-G-S-A-G-L-D-L-R-A-C-L-D-A-P-L-T-L-E-P-G-S-T-H-L-I-P-T-G-M-A-I-H-L-A-D-P-G-Y-A-A-L-I-L-P-R-S-G-M-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-Q-L-M-I-S-T-W-N-R-G-D-T-A-F-V-L-N-P-M-E-R-L-A-Q-L-V-I-V-P-V-V-Q-A-E-L-N-I-V-D-A-F-A-E-S-E-R-G-A-G-G-F-G-S-T-G-R-H"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-L-I-E-F-E-G-V-V-S-E-A-L-P-D-N-R-F-R-V-Q-L-E-N-G-V-E-V-W-A-Y-A-S-G-K-M-Q-K-H-R-I-R-I-L-A-G-D-R-V-K-L-E-M-S-P-Y-D-L-T-K-G-R-I-N-Y-R-H-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-P-R-A-Q-D-V-A-Q-S-D-A-T-L-S-S-P-A-T-P-A-S-Y-E-A-A-M-A-E-L-E-T-L-V-A-S-M-E-S-G-E-L-P-L-E-A-S-L-A-A-Y-R-R-G-A-E-L-V-R-Y-C-Q-Q-V-L-E-R-V-E-Q-Q-V-R-V-L-D-G-D-A-L-K-P-L-A-G-E-G-T-N-E-Q-G-G-A"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-Q-L-L-I-V-A-V-G-H-K-M-P-R-W-I-E-D-G-F-A-E-Y-A-K-R-M-P-P-E-L-R-I-E-L-R-E-I-K-P-E-Q-R-S-G-S-R-T-A-A-T-V-M-Q-L-E-A-A-R-I-E-A-A-L-P-K-G-C-R-I-V-A-L-D-E-R-G-K-D-L-T-T-A-A-L-A-D-A-L-T-G-W-Q-R-E-G-G-D-V-A-L-I-I-G-G-A-D-G-L-D-P-A-L-K-A-R-A-H-M-L-M-R-L-S-S-L-T-L-P-H-G-M-V-R-V-L-L-A-E-Q-L-Y-R-A-W-S-I-T-Q-N-H-P-Y-H-R-V"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-P-K-R-R-R-I-A-L-I-A-H-D-H-K-K-D-D-M-I-A-F-A-Q-T-H-K-A-F-L-M-R-C-D-L-L-A-T-G-T-T-G-G-R-L-Q-D-E-V-G-L-S-V-Q-R-M-L-S-G-P-W-G-G-D-L-Q-I-G-A-Q-L-A-E-G-R-V-D-A-V-I-F-L-R-D-P-M-T-P-Q-P-H-E-P-D-I-N-A-L-V-R-A-C-D-V-H-N-I-P-C-A-T-N-L-A-T-A-D-L-V-M-I-A-L-G-L-A-Q-P-D-P-K-E-I-H-A"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-V-E-D-C-L-K-Q-I-P-N-R-F-E-L-A-L-A-A-T-Y-R-A-R-Q-L-V-Q-G-H-T-P-K-V-D-A-K-D-K-P-T-V-T-A-L-R-E-I-A-A-G-Q-V-G-I-E-M-L-K-K-V-P-S"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 5-hydroxyisourate ### SEQUENCE -M-G-R-L-T-T-H-V-L-D-T-A-A-G-T-P-G-K-D-L-A-I-T-L-F-K-I-V-N-N-L-R-Q-P-I-K-T-V-R-T-N-H-D-G-R-C-E-A-P-L-L-E-G-E-A-L-Q-A-G-I-Y-E-L-D-F-A-V-G-D-Y-Y-R-A-A-G-V-S-L-P-D-P-A-F-L-D-V-V-T-L-R-F-G-V-A-D-A-G-A-H-Y-H-V-P-L-L-V-S-P-W-S-Y-S-T-Y-R-G-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-V-A-D-I-N-K-Q-E-V-V-K-Q-F-A-R-G-T-N-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-R-I-N-E-L-T-P-H-F-K-A-H-M-K-D-H-H-S-R-R-G-L-L-K-M-V-S-R-R-R-R-L-L-D-Y-L-K-K-N-D-A-D-R-Y-R-S-L-I-E-K-L-G-L-R-K"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur , and thus conserves the redox energy in a proton gradient ### SEQUENCE -M-T-D-K-L-A-T-L-Q-S-A-L-E-K-A-L-G-N-R-I-Q-S-L-T-E-A-V-G-E-I-T-L-V-V-K-A-A-D-Y-L-E-T-M-R-T-L-R-D-D-A-T-L-K-F-E-Q-L-I-D-L-C-G-V-D-Y-S-A-Y-G-D-G-A-W-N-G-P-R-F-A-A-V-S-H-L-L-S-V-T-H-N-W-R-V-R-V-R-V-F-A-P-D-D-D-L-P-V-V-A-S-V-V-D-V-W-N-A-A-D-W-F-E-R-E-A-F-D-L-Y-G-L-V-F-E-G-H-P-D-L-R-R-I-L-T-D-Y-G-F-I-G-H-P-F-R-K-D-F-P-V-S-G-Y-V-E-M-R-Y-D-P-V-Q-R-R-V-I-Y-Q-P-V-T-I-E-P-R-E-I-T-P-R-V-I-R-E-D-Q-Y-G-G-L-K-H"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-F-L-F-D-L-F-P-V-I-L-F-F-A-A-F-K-V-A-G-I-Y-V-A-T-T-V-A-M-V-A-T-V-A-Q-I-A-W-V-W-F-K-H-R-K-V-D-A-M-Q-W-L-S-L-L-I-I-V-V-F-G-G-A-T-L-I-F-H-N-D-T-F-I-K-W-K-P-T-V-L-Y-W-M-F-G-V-V-L-L-G-S-A-V-L-L-R-K-N-L-I-R-A-M-M-E-Q-Q-V-S-L-P-E-P-M-W-G-R-L-N-L-V-W-S-L-F-F-L-A-M-G-G-L-N-L-Y-V-A-Y-H-F-D-T-D-V-W-V-N-F-K-L-F-G-S-M-G-L-M-V-V-F-I-L-V-Q-S-V-W-L-A-R-H-M-Q-E-R-P-A-G-A-N-P-Q-D-D-R"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-P-T-L-T-K-A-E-L-A-E-M-L-F-E-Q-V-G-L-N-K-R-E-S-K-D-M-V-E-A-F-F-D-V-I-R-E-A-L-E-Q-G-D-S-V-K-L-S-G-F-G-N-F-Q-L-R-D-K-P-Q-R-P-G-R-N-P-K-T-G-E-I-I-P-I-T-A-R-R-V-V-T-F-H-A-S-Q-K-L-K-A-L-V-E-E-R-V-E-P-M-P-A-S-A-A"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-R-A-R-H-K-K-V-I-D-A-A-K-G-Y-R-G-R-R-N-N-V-Y-R-I-A-K-Q-A-V-M-R-A-G-Q-Y-A-Y-R-D-R-R-N-K-K-R-V-F-R-A-L-W-I-A-R-I-N-A-G-A-R-E-H-G-L-S-Y-S-K-F-M-N-G-L-K-K-A-S-I-E-L-D-R-K-V-L-S-D-M-A-I-H-D-K-V-A-F-A-A-I-V-N-Q-V-K-A-N-V-A"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-R-T-F-N-I-A-T-E-K-S-H-R-I-N-R-E-I-T-A-P-E-I-R-L-T-G-V-E-G-E-Q-L-G-I-V-K-L-F-D-A-L-R-L-A-E-E-K-D-V-D-L-V-E-I-A-P-T-A-Q-P-P-V-C-R-L-M-D-Y-G-K-F-K-Y-Q-E-Q-K-K-A-H-E-A-K-L-K-Q-K-V-I-Q-V-K-E-V-K-F-R-P-G-T-D-D-G-D-Y-E-V-K-L-R-N-L-K-R-F-L-D-E-G-D-R-T-K-I-T-L-R-F-R-G-R-E-M-A-H-Q-E-I-G-A-R-M-L-D-R-L-K-T-D-L-E-E-F-G-Q-V-E-Q-M-P-K-M-E-G-R-Q-M-V-M-M-L-A-P-K-K-R-K"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-T-I-P-I-T-K-R-G-A-E-M-L-K-D-E-L-Q-R-L-K-T-K-E-R-P-A-V-V-N-A-I-A-E-A-R-A-Q-G-D-L-S-E-N-A-D-Y-D-A-A-K-E-R-Q-G-F-I-E-G-R-I-L-E-I-E-S-K-L-A-A-A-Q-V-I-D-P-A-G-L-D-A-D-G-R-I-V-F-G-A-T-I-D-L-E-D-L-D-S-G-K-P-V-T-Y-Q-I-V-G-D-D-E-A-D-L-D-S-G-K-I-S-I-S-S-P-I-A-R-A-L-I-G-K-Y-E-G-D-V-A-T-V-V-A-P-G-G-E-R-E-Y-E-V-R-A-V-K-Y-L"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-T-I-A-D-N-K-K-A-F-F-D-Y-F-V-E-E-R-Y-E-A-G-I-A-L-E-G-W-E-V-K-A-I-R-A-G-R-V-Q-I-K-E-G-Y-V-V-I-R-D-A-E-L-F-L-I-G-A-H-I-S-P-L-Q-S-A-S-T-H-V-K-P-D-P-T-R-T-R-K-L-L-L-H-A-E-E-I-K-K-L-I-G-K-V-E-Q-R-G-Y-T-L-V-P-L-N-L-H-Y-A-R-G-R-V-K-C-E-I-G-L-A-K-G-K-K-L-Y-D-K-R-E-T-E-K-D-R-D-W-Q-R-E-K-A-R-L-M-R-E-K-A"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-V-A-D-I-K-K-S-A-E-Q-K-M-Q-K-S-I-D-A-F-K-A-D-L-A-K-V-R-T-G-R-A-H-T-G-L-L-D-H-V-Q-V-D-Y-Y-G-S-M-V-P-I-S-Q-V-A-N-L-G-L-A-D-A-R-T-I-S-V-Q-P-W-E-K-K-M-V-S-A-V-E-R-A-I-R-D-A-D-L-G-L-N-P-A-T-M-G-E-V-I-R-V-P-M-P-P-L-T-E-E-R-R-K-E-L-T-K-V-V-K-S-E-G-E-D-A-K-V-A-V-R-N-V-R-R-D-A-N-E-Q-F-K-K-L-V-K-D-K-A-I-S-E-D-D-E-R-R-G-Q-D-E-V-Q-K-L-T-D-R-F-V-A-E-V-D-K-L-V-A-E-K-D-K-E-I-M-T-V"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-R-P-I-L-K-M-G-D-S-R-L-L-R-V-A-K-P-V-Q-R-F-Q-T-P-E-L-T-A-L-I-E-D-M-F-D-T-M-D-A-A-R-G-A-G-L-A-A-P-Q-I-G-V-D-L-Q-V-V-I-F-G-F-D-R-N-D-R-Y-P-D-A-P-A-V-P-K-T-V-L-I-N-P-T-I-E-P-L-S-D-A-M-E-D-G-W-E-G-C-L-S-V-P-G-L-R-G-V-V-P-R-Y-T-R-L-R-Y-T-G-Y-D-Q-H-G-H-A-I-D-R-I-A-E-G-F-H-A-R-V-V-Q-H-E-C-D-H-L-Q-G-I-L-Y-P-M-R-V-Q-D-F-T-R-F-G-F-T-E-I-L-F-P-E-L-P-A-H-H-N-D"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-Q-A-N-S-R-A-F-F-L-L-I-A-V-I-A-F-G-L-V-G-Y-A-L-Y-L-Q-H-V-E-G-L-Q-P-C-P-L-C-V-L-Q-R-F-A-F-V-G-I-G-V-F-S-L-L-A-A-L-S-S-A-T-R-L-L-W-H-G-L-G-M-L-S-G-L-G-G-I-F-V-A-G-Y-H-V-S-L-L-L-N-P-K-A-S-C-G-I-D-P-I-E-N-W-V-N-A-L-P-T-A-K-W-L-P-Q-V-F-E-S-D-G-L-C-T-A-P-L-P-P-V-L-G-V-S-I-P-L-W-S-L-I-W-M-V-I-L-A-L-T-L-V-V-A-M-I-R-R-E-R-R"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-S-G-M-G-F-V-A-V-G-V-G-A-A-L-G-A-W-L-R-W-A-F-A-V-L-W-N-A-I-N-P-A-L-P-Y-G-T-L-A-A-N-L-L-G-G-Y-L-I-G-V-A-V-G-F-F-D-T-H-A-S-L-P-P-E-W-R-L-L-A-V-T-G-F-L-G-G-L-T-T-F-S-T-F-S-S-E-V-M-A-N-I-L-A-G-D-Y-A-I-G-M-L-H-V-A-A-H-L-G-G-S-L-F-L-T-M-L-G-L-W-T-V-R-T-L-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-E-K-V-V-N-L-G-N-L-G-D-V-V-R-V-K-D-G-Y-A-R-N-F-L-I-P-N-K-Q-A-R-R-A-T-A-S-A-I-Q-E-F-E-A-R-R-A-E-L-E-K-L-A-A-E-R-L-A-A-A-Q-A-E-G-E-K-L-N-G-L-T-L-Q-L-S-Q-K-A-G-V-D-G-R-L-F-G-S-V-T-N-H-D-I-A-A-A-L-T-A-Q-G-F-K-V-E-K-A-Q-V-R-M-P-N-G-P-L-K-T-V-G-D-H-P-V-A-V-S-L-H-T-D-V-S-V-D-V-T-V-S-V-L-G-E-T-V"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-N-K-K-Q-R-D-A-K-N-K-K-R-F-Q-Q-Q-N-P-L-F-K-R-K-K-F-C-R-F-T-V-A-G-V-E-Q-I-D-Y-K-D-L-D-T-L-K-D-F-I-G-E-N-G-K-I-T-P-A-R-L-T-G-T-R-S-H-Y-Q-R-Q-L-D-T-A-I-K-R-A-R-F-L-A-L-M-P-Y-T-D-Q-H-K-H"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-I-V-H-P-D-Q-S-E-Q-V-P-A-M-I-E-R-Y-K-S-T-V-T-S-Q-G-G-Q-V-H-R-V-E-D-W-G-R-R-Q-L-A-Y-M-I-Q-K-L-A-K-A-H-Y-V-C-V-N-I-E-C-G-K-E-T-L-A-E-L-E-H-A-F-K-F-N-D-A-V-L-R-H-L-I-V-Q-T-K-K-A-E-T-A-P-S-P-M-M-K-E-V-Q-R-E-E-A-K-K-A-A-A-Q-S-E-Q-A-A"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-K-K-S-G-S-A-S-G-R-N-L-R-I-A-D-Q-I-Q-R-D-L-A-E-L-I-Q-R-E-I-K-N-P-A-M-G-L-V-T-L-Q-S-V-S-L-T-P-D-Y-A-H-A-K-I-Y-F-T-V-L-G-A-E-P-D-A-A-A-A-I-L-N-E-K-A-G-Y-L-H-S-L-L-F-K-R-L-H-I-H-T-V-P-T-L-H-F-H-Y-D-G-S-V-E-R-G-I-E-M-S-R-L-I-D-Q-A-N-A-S-R-A-K-D-D"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-H-L-T-D-L-I-E-K-T-L-T-A-M-G-Y-E-L-V-E-V-E-R-A-P-A-G-L-L-R-V-Y-I-D-Q-A-E-T-G-I-V-I-E-D-C-E-K-V-S-H-Q-L-T-R-V-F-E-V-E-N-V-N-Y-E-R-L-E-V-S-S-P-G-L-D-R-P-L-R-T-L-V-D-F-A-R-F-A-G-L-E-A-K-V-T-L-R-L-P-V-N-G-Q-K-N-F-T-G-I-V-Q-A-P-A-G-E-P-G-Q-E-R-I-G-L-E-F-E-G-K-D-G-P-A-L-L-E-F-T-L-S-E-L-D-R-A-R-L-V-P-V-L-D-F-K-G-N-R-N-K-G-N-K-Q"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-S-N-K-G-Q-L-L-Q-D-P-F-L-N-A-L-R-K-E-H-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-N-I-E-S-F-D-Q-Y-V-V-L-L-R-N-T-V-T-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-A-V-N-F-R-V-D-E-A-S-D-A"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-K-G-Q-I-A-G-L-M-K-Q-A-Q-Q-M-Q-E-N-M-K-K-M-Q-E-Q-L-S-Q-I-E-V-E-G-V-S-G-A-G-L-V-K-V-V-M-T-C-K-N-D-V-K-R-V-S-I-D-P-S-L-L-A-E-G-E-D-K-E-L-L-E-D-L-V-A-A-A-F-N-D-A-V-R-K-A-E-A-T-T-Q-E-K-M-G-T-V-T-S-G-L-G-G-M-A-S-M-L-P-P-G-F-K-L-P-F"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-L-I-T-L-F-L-L-L-L-L-L-A-I-Q-Y-P-L-W-L-G-K-G-G-W-L-R-V-W-D-M-Q-K-Q-V-A-S-Q-N-Q-R-N-A-E-L-K-Q-R-N-L-K-L-E-G-E-V-K-D-L-K-E-G-T-G-A-I-E-E-R-A-R-Y-E-L-G-M-V-K-D-D-E-G-F-V-Q-F-V-A-P-A-P-K-T-S-E-T-P-L-P-P-P-A-A-L-Q-P-N-H-R-H"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-L-K-I-A-Q-E-L-R-A-G-N-V-F-M-I-G-N-D-P-M-V-V-L-K-T-E-Y-S-R-S-G-R-N-A-A-V-V-K-M-K-Y-K-N-L-L-T-G-A-P-S-E-S-V-F-K-A-D-D-K-M-D-Q-I-I-L-D-K-K-E-C-T-Y-S-Y-F-A-D-P-M-Y-V-F-M-D-T-D-Y-N-Q-Y-E-V-E-A-D-S-M-G-D-A-I-H-Y-L-E-D-G-M-A-A-E-V-T-F-Y-N-E-K-A-I-S-V-E-L-P-T-T-L-V-R-E-I-E-Y-T-E-P-A-V-K-G-D-T-S-S-G-K-V-L-K-M-A-K-I-K-G-G-F-E-I-Q-V-P-L-F-C-S-T-G-D-K-I-E-I-D-T-R-T-H-E-Y-R-S-R-A-N"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-S-G-A-I-Y-G-I-G-T-D-I-I-Q-I-E-R-V-E-G-V-M-Q-R-T-H-G-R-F-A-E-K-V-L-G-P-D-E-L-R-I-Y-Q-A-R-K-A-R-S-E-R-R-G-L-A-F-L-A-T-R-F-A-A-K-E-A-V-S-K-A-I-G-L-G-M-H-W-P-M-T-W-R-A-V-Q-T-L-N-L-P-S-G-Q-P-V-V-R-Y-S-G-E-L-A-D-W-I-A-Q-R-G-L-H-I-Q-I-S-V-T-D-E-R-D-Y-A-V-A-F-A-V-A-E-L-Q-S-K-L-S-A"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-D-N-I-E-Q-R-V-K-K-I-V-A-E-Q-L-G-V-A-E-A-D-I-K-N-E-S-S-F-V-N-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-D-E-F-G-M-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-Q-A-I-D-Y-A-R-A-N-V-K-A"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-S-A-S-D-T-H-F-S-L-F-G-L-P-E-H-F-E-V-D-D-G-A-L-N-A-A-Y-R-T-V-Q-S-R-A-H-P-D-R-H-A-H-A-S-D-A-E-R-R-V-A-M-Q-W-A-T-R-A-N-E-A-Y-Q-T-L-R-D-P-L-K-R-A-T-Y-L-L-H-L-R-G-V-D-V-Q-A-E-N-N-T-A-M-P-P-A-F-L-M-Q-Q-L-E-W-R-E-S-L-A-D-A-K-A-A-G-D-L-D-A-L-D-D-L-L-A-M-L-R-G-E-K-R-A-R-Y-Q-T-L-A-G-L-L-N-G-G-G-H-D-A-A-A-A-D-A-V-R-Q-L-M-F-I-E-K-I-E-R-D-T-A-E-A-I-D-R-L-D-D"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-L-I-E-Q-I-E-Q-E-E-I-K-R-L-T-A-N-K-T-I-P-P-F-A-P-G-D-T-V-I-V-N-V-N-V-V-E-G-N-R-K-R-V-Q-A-Y-E-G-V-V-I-A-K-R-N-R-G-L-N-S-S-F-I-V-R-K-I-S-S-G-E-G-V-E-R-T-F-Q-L-Y-S-P-L-L-A-S-I-E-V-K-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-E-R-S-G-K-S-A-R-I-K-E-K-L-S-F-K-R-K-E-V-A-A-Q"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-R-P-G-A-G-A-N-P-S-L-P-D-D-L-V-E-V-G-Y-V-G-G-A-Y-G-V-R-G-W-I-K-V-Q-P-H-G-D-A-E-A-L-L-H-A-S-T-W-W-L-K-P-A-A-G-A-P-A-V-S-S-D-W-R-V-L-P-V-G-T-S-R-E-H-S-G-S-V-V-A-G-S-P-A-V-P-D-R-N-V-A-E-A-L-R-G-C-T-V-W-V-R-R-A-E-F-P-A-P-A-D-D-E-F-Y-W-V-D-L-I-G-S-T-V-V-N-E-Q-Q-E-T-L-G-T-V-A-G-L-I-D-N-G-A-H-Q-I-L-R-I-V-D-E-G-G-T-E-R-L-V-P-F-V-E-V-Y-V-K-S-V-D-V-A-G-K-H-I-V-V-D-W-G-L-D-Y"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-V-E-K-L-A-A-R-F-P-Q-L-L-L-R-D-A-D-I-A-V-K-T-I-L-D-A-M-S-D-A-L-A-D-G-H-R-I-E-I-R-G-F-G-S-F-G-L-N-R-R-P-P-R-V-G-R-N-P-K-S-G-E-K-V-L-V-P-E-K-R-V-P-H-F-K-A-G-K-E-L-R-E-R-V-D-R-S-L-E-R-Q-G-D-S-S-S-E-G-E-P-V-S-L-T-A-V-K-A-A-R-Q-A-G-G-H-H-A-A-G-F-P-A-E-A-T-P-T-L-V-M-S-R"} +{"text": "### FUNCTION Oxygen-binding protein May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes The oxygen-binding site contains two iron atoms ### SEQUENCE -M-P-V-I-Q-W-S-E-A-L-H-L-G-D-A-A-T-D-A-N-H-A-A-F-C-T-L-L-N-A-V-A-D-A-S-E-A-D-F-V-S-A-L-D-A-F-I-A-H-T-E-V-H-F-A-E-E-N-A-W-M-E-A-A-D-F-P-P-L-H-C-H-R-N-E-H-D-N-V-L-A-L-C-R-E-V-R-R-R-A-A-D-G-D-M-A-L-G-R-R-L-V-T-E-L-P-E-W-F-A-Q-H-V-D-V-M-D-R-M-M-T-T-W-L-A-Q-R-G-P-D-A-R-E-E-A-A-A"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-Q-E-S-T-M-T-E-R-Q-A-L-E-T-A-V-L-G-G-G-C-F-W-C-T-E-A-V-F-Q-Q-V-Q-G-V-H-S-V-V-S-G-Y-A-G-G-H-L-E-R-P-T-Y-R-A-V-C-G-G-D-T-G-H-A-E-V-V-R-V-E-F-D-P-A-V-I-P-Y-R-E-I-L-D-I-F-F-A-T-H-D-P-T-T-L-E-R-Q-G-N-D-I-G-P-Q-Y-R-S-A-V-F-A-Q-S-P-E-Q-F-A-E-A-G-A-T-I-R-A-L-S-A-A-N-V-F-D-A-P-I-V-T-E-V-V-D-A-S-G-G-K-V-P-F-W-Q-A-E-D-E-H-Q-N-Y-F-R-D-H-P-A-Q-G-Y-C-A-F-V-I-S-P-K-V-A-K-F-R-E-R-F-A-H-R-L-Q-A"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-F-C-G-H-A-A-T-Q-V-I-D-T-R-M-S-E-E-G-D-T-V-R-R-R-R-R-C-E-S-C-D-R-R-F-T-T-Y-E-R-I-E-L-F-F-P-A-V-V-K-K-N-G-S-R-V-D-Y-D-R-N-K-V-K-D-S-M-R-L-A-L-R-K-R-P-V-S-A-E-A-I-D-E-A-I-A-R-I-E-E-K-L-L-S-H-G-E-K-E-I-G-S-D-R-I-G-E-L-V-M-R-E-L-K-R-L-D-K-I-G-Y-I-R-F-A-S-V-Y-R-S-F-E-D-V-S-E-F-R-D-M-L-D-E-F-R-Q"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-D-H-G-F-Y-P-T-N-L-E-G-E-G-L-R-I-G-I-V-Q-A-R-F-N-E-P-V-C-E-A-L-R-E-A-C-V-A-E-L-E-Q-L-G-V-A-G-E-D-V-L-L-V-T-V-P-G-A-L-E-V-P-L-A-L-Q-K-M-A-E-S-G-Q-F-D-A-L-I-A-L-G-A-V-I-R-G-E-T-Y-H-F-E-L-V-S-N-E-S-G-A-G-I-T-R-V-C-L-D-F-N-I-A-I-A-N-G-I-L-T-T-D-T-D-A-Q-A-H-A-R-T-R-E-K-G-R-D-C-A-R-T-A-I-E-M-A-N-L-T-A-A-L-D-G-L-Q-D-H-G-Q-D-D-E-N-E"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-T-Q-D-N-S-P-A-K-P-K-A-P-P-K-S-A-R-R-R-A-R-E-L-A-L-Q-G-L-Y-Q-W-L-L-N-R-N-D-P-G-V-V-E-A-H-L-H-D-A-Q-G-F-N-K-A-D-R-A-H-F-D-A-L-L-H-G-A-I-R-E-E-A-T-L-T-E-S-F-T-P-F-L-D-R-P-V-A-E-L-S-P-V-E-R-A-A-L-L-V-G-A-Y-E-L-V-H-C-V-D-I-P-Y-K-V-V-I-N-E-A-V-E-L-A-K-T-F-G-G-V-E-G-Y-K-Y-V-N-G-V-L-D-K-L-A-A-Q-V-R-A-V-E-V-A-A-R-R"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-T-S-Q-Q-I-D-A-E-A-L-Y-Q-S-L-V-A-Q-L-R-T-R-M-A-G-T-P-A-G-D-W-S-V-A-G-I-V-S-G-G-A-W-I-A-A-R-L-A-L-D-L-G-L-R-E-Y-G-I-V-N-V-A-L-H-R-D-D-Y-A-K-K-G-L-H-A-Q-A-Q-P-T-T-L-P-F-E-V-E-E-R-R-I-L-L-V-D-D-V-L-A-T-G-R-T-I-R-A-A-I-N-E-L-F-D-Y-G-R-P-A-A-V-E-L-A-V-L-V-D-R-G-E-R-Q-L-P-I-A-P-D-Y-I-G-E-R-I-A-L-A-A-D-E-S-L-V-L-R-Q-E-G-E-G-A-S-A-R-F-T-F-T-R-E-P-K-T-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-E-P-A-R-P-A-P-A-P-V-P-V-H-G-T-L-L-A-F-D-Y-G-E-K-R-I-G-V-A-L-G-N-S-I-T-R-S-A-R-A-L-E-V-I-P-N-R-S-V-E-Y-R-F-T-Q-I-T-R-L-V-N-A-W-Q-P-V-G-F-V-V-G-M-P-V-H-P-E-G-E-D-Q-P-M-I-K-L-A-K-R-F-G-N-Q-L-H-G-R-Y-G-L-P-V-T-W-V-D-E-R-Y-S-S-I-A-A-Q-D-A-G-A-T-D-D-V-L-D-A-E-A-A-R-I-I-L-Q-Q-F-F-D-E-S-H-A"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-L-R-P-L-H-D-R-V-I-V-K-R-L-D-N-E-T-K-T-A-S-G-I-V-I-P-D-A-A-A-E-K-P-D-Q-G-E-V-L-A-I-G-P-G-K-K-D-D-K-G-N-P-I-A-L-D-V-K-V-G-D-R-V-L-F-G-K-Y-A-G-Q-A-V-K-V-D-G-Q-E-L-L-V-M-R-E-E-D-I-M-A-V-V-T-K"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-A-L-P-R-Q-P-L-S-L-K-A-R-A-L-G-Y-L-S-R-R-E-H-S-R-A-E-L-R-R-K-L-A-P-H-A-E-S-V-D-E-V-E-A-L-L-D-W-L-E-G-E-N-W-L-S-N-T-R-F-A-E-S-V-V-H-R-R-A-S-R-Y-G-T-A-R-L-M-Q-E-L-K-T-H-E-L-G-D-D-A-L-G-E-V-K-A-Q-L-Q-A-S-E-M-A-R-A-K-A-V-W-E-R-R-F-G-R-P-P-A-D-M-A-E-R-A-K-Q-V-R-F-M-V-A-R-G-F-S-R-A-V-V-S-R-I-I-Q-G-A-D-A-L-L-D-D-G-D-E-P-V"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-L-A-L-R-P-E-H-H-D-S-I-T-L-R-I-E-A-E-P-A-A-E-A-E-D-A-D-D-A-L-A-G-A-E-M-L-T-L-D-L-T-V-Q-H-G-D-A-L-K-A-A-A-R-K-A-L-P-K-Q-K-D-I-E-A-W-I-A-P-A-L-F-A-D-A-Q-L-N-V-R-F-V-D-E-E-E-G-R-T-L-N-H-T-Y-R-G-K-D-Y-A-T-N-V-L-T-F-S-Y-A-E-T-E-D-D-P-V-A-A-D-I-V-L-C-C-P-V-V-E-Q-E-A-K-D-Q-G-K-P-L-R-A-H-Y-A-H-L-I-V-H-G-A-L-H-A-Q-G-Y-D-H-E-D-P-A-Q-A-E-E-M-E-G-I-E-T-E-V-L-A-G-L-G-F-P-D-P-Y-A-D-R"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-I-A-G-T-L-I-E-K-N-P-P-H-L-L-V-D-C-H-G-V-G-Y-E-I-D-V-P-M-S-T-F-Y-N-L-P-A-T-G-E-K-V-A-L-L-T-Q-Q-I-V-R-E-D-A-H-L-L-Y-G-F-G-T-A-A-E-R-E-T-F-R-Q-L-I-K-I-S-G-I-G-A-R-I-A-L-A-V-L-S-G-M-S-V-A-E-L-A-Q-A-V-T-L-Q-E-A-G-R-L-T-R-I-P-G-I-G-K-K-T-A-E-R-L-L-L-E-L-K-G-K-L-G-A-D-L-G-T-V-P-G-G-P-A-V-S-D-D-A-V-D-V-L-N-A-L-L-A-L-G-Y-S-D-K-E-A-A-Q-A-I-K-Q-V-P-A-G-T-G-V-S-E-G-I-K-L-A-L-K-A-L-S-K-G"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters ### SEQUENCE -M-N-A-V-A-Q-A-A-T-P-D-V-N-E-V-P-A-P-L-V-F-T-D-S-A-A-D-K-V-K-Q-L-I-E-E-E-G-N-P-E-L-K-L-R-V-F-V-Q-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-D-T-N-E-D-D-T-T-M-T-K-N-G-V-T-L-L-I-D-S-M-S-Y-Q-Y-L-V-G-A-E-I-D-Y-K-E-D-I-N-G-A-Q-F-V-I-K-N-P-N-A-S-T-T-C-G-C-G-S-S-F-S-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-S-A-K-P-H-E-V-K-R-N-W-F-V-I-D-A-T-D-K-V-L-G-R-V-A-S-E-V-A-L-R-L-R-G-K-H-K-P-E-F-T-P-H-V-D-T-G-D-F-I-I-V-I-N-A-A-K-L-R-V-T-G-A-K-T-T-D-K-K-Y-Y-R-H-S-G-Y-P-G-G-I-Y-E-T-T-F-G-K-M-Q-Q-R-F-P-G-R-A-L-E-K-A-V-K-G-M-L-P-K-G-P-L-G-Y-A-M-I-K-K-L-K-V-Y-A-E-G-S-H-P-H-E-A-Q-Q-P-Q-V-L-E-I"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-S-V-N-K-V-I-I-V-G-N-L-G-A-D-P-E-T-R-Y-M-P-S-G-D-A-V-T-N-I-R-V-A-T-T-D-R-Y-K-D-K-A-S-G-E-M-R-E-A-T-E-W-H-R-I-A-F-F-G-R-L-A-E-I-A-G-E-Y-L-K-K-G-S-Q-V-Y-V-E-G-R-L-K-T-R-Q-W-E-K-D-G-Q-K-Q-Y-S-T-E-I-V-A-E-Q-M-Q-M-L-G-S-R-Q-G-M-G-G-E-G-G-G-G-G-G-G-Y-S-R-G-E-S-S-G-G-G-G-Y-G-G-G-R-A-Q-G-G-G-G-M-S-R-G-E-G-G-G-G-Q-G-G-G-A-R-R-Q-Q-A-P-S-N-G-F-E-D-M-D-D-D-I-P-F"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-I-K-L-I-V-G-L-G-N-P-G-A-E-Y-A-A-T-R-H-N-A-G-F-W-L-V-D-Q-L-A-R-M-G-H-V-T-L-R-N-E-T-R-F-H-G-Y-A-A-R-A-T-L-W-S-H-E-V-W-L-L-Q-P-Q-T-F-M-N-R-S-G-L-A-T-V-A-L-A-R-F-Y-K-I-L-P-D-E-I-L-V-V-H-D-E-L-D-L-L-P-G-A-V-K-L-K-L-G-G-G-S-G-G-H-N-G-L-K-D-I-A-A-H-L-T-T-Q-Q-F-W-R-L-R-V-G-I-G-H-P-R-N-L-L-P-P-G-T-A-P-S-G-Q-H-D-V-A-N-F-V-L-K-A-P-R-R-E-E-Q-E-L-I-D-R-A-I-D-R-S-L-D-A-L-P-D-L-V-A-G-N-A-E-R-A-M-M-R-L-H-T-T-G"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-D-Q-Q-Q-Q-Q-P-G-Q-D-G-Q-P-F-F-N-I-Q-R-V-Y-L-K-D-L-S-L-E-Q-P-N-S-P-H-I-F-L-E-Q-E-Q-P-T-V-E-V-Q-V-D-V-A-A-T-Q-L-A-E-G-V-F-E-V-T-V-I-G-T-V-T-T-K-V-K-E-K-V-A-F-L-V-E-A-K-Q-A-G-I-F-D-I-R-N-V-P-V-E-Q-M-D-P-L-L-G-I-A-C-P-T-I-V-Y-P-Y-L-R-S-N-I-A-D-T-I-G-R-A-G-F-Q-P-I-H-L-A-E-I-N-F-Q-A-L-Y-E-Q-R-L-A-S-A-M-E-E-A-Q-A-A-G-G-N-G-G-I-V-M-P-D-G-S-K-A-T-H"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-L-L-N-I-L-Q-Y-P-D-P-R-L-H-K-V-A-K-P-V-A-V-V-D-D-R-I-R-K-L-V-A-D-M-A-E-T-M-Y-D-A-P-G-I-G-L-A-A-T-Q-V-D-V-H-E-R-V-I-T-I-D-V-S-E-S-R-D-E-L-R-V-F-I-N-P-E-I-V-W-A-S-E-A-R-K-V-W-D-E-G-C-L-S-V-P-D-I-Y-D-K-V-E-R-P-D-R-V-R-V-R-A-L-N-E-K-G-E-S-F-E-L-E-T-D-G-L-L-A-V-C-I-Q-H-E-M-D-H-L-M-G-K-V-F-V-E-Y-L-S-P-L-K-Q-N-R-I-K-I-K-L-K-K-H-Q-L-E-R-A-R"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-A-L-E-L-S-D-V-K-R-I-A-H-L-A-R-I-E-V-S-D-G-E-A-A-Q-T-L-T-Q-L-N-Q-F-F-T-L-V-E-Q-M-Q-A-V-D-T-T-G-I-E-P-M-A-H-P-I-E-Q-V-Q-A-P-A-Q-R-L-R-E-D-A-V-T-E-P-D-R-R-A-D-Y-Q-Q-C-A-P-S-T-E-A-G-L-Y-L-V-P-K-V-I-E"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-K-Y-R-I-K-K-N-D-D-F-Q-K-V-F-R-R-G-K-S-F-A-N-R-Q-F-V-V-Y-T-L-K-Q-E-G-S-N-H-F-R-I-G-L-S-V-S-K-K-I-G-N-A-V-C-R-N-R-I-K-R-Y-I-R-Q-S-F-H-E-L-E-S-Q-I-N-P-E-N-E-Y-I-I-I-A-R-K-P-A-A-N-M-D-F-H-E-V-K-K-S-L-I-H-V-L-K-V-G-R-V-L-K-Q-K-P-N-N-S-K"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-R-G-M-G-N-M-Q-G-M-M-K-Q-M-Q-K-M-Q-K-E-M-A-K-A-Q-A-D-L-E-A-Q-E-F-T-G-T-A-G-G-G-M-V-T-V-K-A-T-G-K-R-V-I-T-D-V-V-I-N-E-E-V-V-D-P-E-D-I-E-M-L-Q-D-L-V-L-A-A-T-N-D-V-L-K-Q-I-E-D-T-T-S-Q-T-M-G-K-F-T-Q-G-L-N-I-P-G-M"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-T-K-L-I-D-S-F-M-K-L-P-G-I-G-P-K-S-A-A-R-L-A-F-Y-V-L-D-M-K-E-D-D-V-L-D-F-A-K-A-L-V-D-A-K-R-N-L-S-F-C-S-V-C-G-H-I-T-D-K-D-P-C-Y-I-C-A-D-T-S-R-D-R-S-V-I-C-V-V-Q-E-S-K-D-V-I-A-M-E-K-M-R-D-F-H-G-L-Y-H-V-L-H-G-T-I-S-P-M-D-G-I-G-P-E-D-I-N-I-P-D-L-L-K-R-L-Q-D-D-T-I-E-E-V-I-L-A-T-N-P-N-V-E-G-E-A-T-A-M-Y-I-S-R-L-L-K-P-S-G-I-K-V-T-R-I-A-H-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-M-E-G-R-R-E-V"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-K-R-F-M-Q-I-W-K-P-A-V-I-G-F-L-L-L-T-L-V-C-G-V-L-Y-P-G-V-V-T-V-F-A-G-V-A-F-H-D-K-A-N-G-S-I-I-E-E-K-L-A-D-G-T-T-G-K-V-G-S-A-E-I-G-Q-T-F-T-E-P-E-Y-L-I-G-R-A-A-S-D-G-V-A-T-N-L-N-P-T-S-E-E-Q-K-Q-L-V-E-K-R-I-A-W-W-H-K-L-D-P-T-N-N-R-V-I-P-M-D-L-V-T-A-S-A-S-G-V-D-P-D-I-S-E-A-A-A-A-Y-Q-V-D-R-I-S-R-E-R-G-I-S-T-K-E-V-K-E-I-I-A-E-H-T-S-N-R-L-L-G-F-W-G-E-P-T-V-N-V-L-Q-V-N-L-A-L-D-R-L-K-M"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-D-A-R-D-I-I-K-R-P-V-V-T-E-E-S-T-S-I-L-D-D-K-K-Y-T-F-E-V-D-T-R-A-T-K-T-Q-V-K-Y-A-V-E-E-I-F-D-V-K-V-A-K-V-N-V-M-N-Y-K-G-K-L-K-R-M-G-R-Y-A-G-Y-T-N-K-R-R-K-A-I-V-T-V-T-A-D-S-K-E-I-Q-F-F-E-V"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-H-V-K-K-G-D-K-V-K-V-I-T-G-K-D-K-G-K-S-G-K-V-L-A-A-F-P-K-K-D-R-V-L-I-E-G-I-N-M-V-K-K-H-T-K-P-S-N-V-N-P-Q-G-G-I-L-N-V-E-A-P-I-H-V-S-N-V-M-L-I-D-P-K-T-G-E-P-T-R-V-G-Y-E-V-K-G-D-K-K-V-R-V-A-K-K-S-G-E-V-I-D-K"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-T-I-V-I-P-A-G-V-T-V-T-L-N-G-S-T-A-T-V-K-G-P-K-G-E-L-V-K-E-F-N-P-E-I-T-I-K-I-E-G-N-E-I-N-V-S-R-P-T-D-N-K-N-H-R-A-L-H-G-T-T-R-A-I-L-N-N-M-V-V-G-V-S-E-G-Y-E-K-K-L-E-L-I-G-V-G-Y-R-A-Q-K-Q-G-D-K-L-V-L-N-V-G-Y-S-H-P-V-E-F-V-A-P-K-G-V-D-I-E-V-P-A-N-T-Q-V-I-V-K-G-Y-N-K-E-H-V-G-E-L-A-A-N-I-R-A-V-R-P-P-E-P-Y-K-G-K-G-I-R-Y-E-G-E-H-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-T-K-I-D-K-N-K-V-R-K-K-R-H-A-R-V-R-S-K-I-S-G-T-E-S-R-P-R-L-N-V-F-R-S-N-K-N-I-Y-A-Q-I-I-D-D-V-N-G-V-T-L-A-S-A-S-N-L-D-K-D-F-G-S-A-E-S-K-V-D-A-A-S-K-V-G-E-L-V-A-K-R-A-S-E-K-G-I-T-S-V-T-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-N-G-L-E-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-P-E-Q-I-D-G-N-K-L-D-L-E-E-R-V-V-T-I-N-R-V-A-K-V-V-K-G-G-R-R-F-R-F-T-A-L-V-V-V-G-D-K-N-G-H-V-G-F-G-T-G-K-A-Q-E-V-P-D-A-I-R-K-A-V-E-D-A-K-K-N-M-V-L-V-P-T-V-D-T-T-I-P-H-T-V-V-G-H-F-G-G-G-E-I-L-L-K-P-A-S-A-G-S-G-V-T-A-G-G-P-V-R-A-V-L-E-L-A-G-V-A-D-V-S-S-K-S-L-G-S-N-T-P-I-N-M-V-R-A-T-I-D-G-I-K-Q-L-K-N-A-E-D-V-A-K-L-R-G-K-T-V-E-E-L-L-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-S-E-G-S-R-K-E-R-N-R-V-G-R-G-T-G-S-G-N-G-K-T-S-G-R-G-H-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-L-P-L-F-R-R-I-P-K-R-G-F-T-N-I-N-R-K-E-F-A-I-V-N-L-D-V-L-N-R-F-E-D-G-T-E-V-T-P-E-L-L-V-E-T-G-I-I-R-N-E-K-S-G-I-K-I-L-S-N-G-N-I-E-K-K-L-T-V-K-A-N-K-F-S-A-A-A-K-E-A-I-E-A-A-G-G-K-T-E-V-I"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-Y-M-A-K-P-G-E-V-E-R-K-W-Y-V-I-D-A-T-G-V-S-L-G-R-L-S-S-E-V-A-S-I-L-R-G-K-N-K-P-Q-F-T-P-H-I-D-T-G-D-F-V-I-I-I-N-A-G-K-I-G-L-T-G-K-K-A-T-D-K-I-Y-Y-R-H-S-Q-Y-P-G-G-L-K-S-R-T-A-G-E-M-R-T-N-N-P-E-K-L-L-E-L-S-I-K-G-M-L-P-K-N-S-L-G-R-Q-L-F-K-K-L-H-V-Y-G-G-S-E-H-E-H-A-A-Q-Q-P-E-V-Y-E-L-R-G"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-D-L-K-N-L-T-Q-E-E-R-S-E-L-S-L-I-D-V-A-H-F-I-L-E-Q-R-K-E-T-I-L-F-P-E-L-V-K-E-I-Q-A-F-L-G-L-K-D-A-E-I-R-E-R-L-V-Q-F-Y-T-D-M-N-I-D-G-N-F-I-S-L-G-N-N-T-W-G-L-R-A-W-Y-P-M-D-A-I-D-E-E-V-Q-T-Q-T-T-P-K-K-K-R-K-S-D-D-D-E-D-E-D-E-E-I-L-D-D-D-V-D-Y-D-D-E-E-I-V-E-E-L-G-E-E-E-I-S-L-A-D-V-L-L-D-E-D-E-D-D-D-D-H-L-P-D-G-I-E-G-D-L-A-T-V-E-D-D-Y-T-D-G-D-Y-T-E-D-P-E-D-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-L-Q-P-H-L-V-I-G-S-A-F-T-F-G-D-A-F-F-T-L-F-A-F-A-I-L-L-V-L-I-R-I-Y-A-W-K-P-L-M-G-I-M-K-E-R-E-E-H-I-G-S-E-I-D-A-A-E-E-N-R-A-Q-S-E-K-L-L-A-E-Q-K-S-V-L-Q-Q-A-R-V-E-S-Q-T-M-I-E-N-A-K-Q-L-G-E-K-E-R-E-E-I-V-K-T-A-R-R-E-S-E-R-I-K-E-E-A-K-S-D-I-A-R-E-K-E-D-A-I-S-A-L-R-E-Q-V-G-S-L-S-V-L-I-A-S-K-V-I-E-K-N-L-D-E-K-E-Q-S-N-L-I-Q-D-Y-I-E-R-L-G-D-D-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-K-D-L-E-V-A-G-R-Y-A-N-A-L-F-Q-V-A-Q-D-K-D-L-V-D-V-F-S-E-E-L-T-E-L-K-A-A-L-K-A-N-K-D-F-V-K-L-L-E-N-P-T-F-T-T-E-Q-K-K-N-L-A-S-A-V-F-E-K-I-N-P-T-L-R-D-F-I-Y-L-L-I-D-R-S-R-E-D-Y-L-S-V-I-A-D-V-Y-Q-K-R-V-N-D-L-R-G-V-A-D-A-D-V-Y-S-V-V-P-L-S-E-Q-E-L-T-A-L-S-R-V-F-A-T-K-M-N-K-T-K-L-N-I-Q-N-H-I-D-K-S-L-L-G-G-V-K-V-V-I-G-T-R-I-Y-D-D-S-L-K-T-K-L-K-D-M-E-R-Q-I-K-A"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-M-N-R-V-V-L-V-G-R-L-T-K-D-P-D-L-R-Y-T-P-A-G-V-A-V-A-T-F-T-L-A-V-N-R-T-F-T-N-Q-N-G-E-R-E-A-D-F-I-N-C-V-V-W-R-K-P-A-E-N-V-A-N-F-L-K-K-G-S-M-A-G-V-D-G-R-V-Q-T-R-N-Y-E-D-N-D-G-K-R-V-F-V-T-E-V-V-A-E-S-V-Q-F-L-E-P-K-N-N-N-V-E-G-A-T-S-N-N-Y-Q-N-K-A-N-Y-S-N-N-N-Q-T-S-S-Y-R-A-D-T-S-Q-K-S-D-S-F-A-S-E-G-K-P-I-D-I-N-E-D-D-L-P-F"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Y-F-L-Y-V-G-V-F-G-A-L-G-G-M-C-R-Y-A-M-N-L-W-L-G-G-G-D-F-P-S-A-T-L-A-V-N-L-I-G-C-F-L-L-A-F-L-M-R-F-L-A-E-K-S-R-V-S-L-V-L-L-N-G-I-G-T-G-F-I-G-A-F-T-T-F-S-A-F-S-V-D-T-I-Q-L-V-Q-S-G-A-W-L-F-A-V-S-Y-V-L-A-S-F-I-G-G-L-I-M-V-K-F-G-R-M-L-S-N-K-L-L-N-R-G-E-H-R-V-G"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-V-N-F-L-L-V-G-F-G-A-A-L-G-A-M-L-R-Y-G-I-S-V-L-V-K-S-K-W-K-T-N-F-P-S-A-T-F-F-I-N-I-T-G-S-F-L-L-G-F-L-V-S-S-A-L-G-P-V-W-Q-L-F-L-G-T-G-F-M-G-G-Y-T-T-F-S-T-F-K-V-E-S-M-E-L-K-W-K-T-N-Y-R-V-L-F-S-Y-L-G-F-T-Y-V-F-G-L-I-A-A-F-L-G-M-M-L-G-V"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-K-K-M-L-V-E-F-R-D-F-A-L-K-G-N-V-L-D-L-A-V-A-V-V-I-G-A-A-F-G-K-I-V-S-S-L-V-D-N-I-I-M-P-L-V-G-V-L-L-G-G-L-D-F-T-D-L-S-F-K-V-G-K-S-V-I-Q-Y-G-A-F-I-Q-S-I-V-D-F-I-I-I-A-F-A-I-F-I-F-V-K-V-L-T-S-F-I-K-K-K-E-Q-T-V-E-E-T-P-V-P-P-T-E-E-Y-L-K-E-I-R-D-L-L-K-E-Q-Q-K"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-G-L-S-N-K-F-K-S-F-F-F-L-D-E-E-E-E-Y-Y-E-E-E-V-A-R-E-P-E-P-M-Q-K-K-T-K-K-E-K-P-N-K-N-R-F-Y-A-V-E-E-D-D-A-K-V-V-S-M-Q-G-A-Q-F-S-S-R-M-V-L-A-E-P-R-V-Y-A-E-A-Q-E-L-A-D-Y-L-K-E-Y-K-S-V-V-V-N-L-Q-R-I-S-H-D-Q-A-T-R-I-V-D-F-L-S-G-T-V-Y-A-L-G-G-D-I-Q-R-V-G-N-N-I-F-L-C-T-P-D-N-V-E-V-D-G-S-I-S-E-M-L-D-E-Q-N-F-M"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-E-I-K-V-H-I-G-K-T-V-A-L-M-N-D-N-I-D-T-D-Q-I-I-P-K-S-F-L-K-R-I-E-R-T-G-F-G-E-F-L-F-D-S-W-R-Y-L-P-N-R-K-P-N-P-D-F-P-L-N-A-L-D-R-Q-E-A-T-I-L-I-T-G-E-N-F-G-C-G-S-S-R-E-H-A-A-W-A-L-L-D-Y-R-F-R-V-I-I-A-G-S-Y-S-D-I-F-Y-M-N-C-T-K-N-G-V-L-P-I-V-L-P-R-E-A-R-E-K-L-A-K-I-A-A-E-E-N-V-T-I-D-L-P-N-Q-Q-V-I-S-S-V-G-T-Y-P-F-E-I-D-A-T-W-K-N-K-F-I-N-G-L-D-D-I-A-I-T-F-E-H-I-D-A-I-K-A-Y-E-Q-K-V-D-S-I"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-N-R-E-E-Q-L-G-V-L-E-S-L-L-F-A-A-G-D-A-G-L-S-T-E-Q-L-T-E-V-M-E-I-T-H-I-E-A-L-N-L-L-E-L-L-S-E-R-Y-N-E-S-A-D-R-G-L-I-L-L-E-L-A-G-T-F-Q-L-A-T-K-K-A-H-A-E-F-L-R-K-L-V-E-V-P-S-N-T-V-L-S-Q-A-S-L-E-T-L-A-I-I-A-Y-R-Q-P-V-T-R-M-E-V-D-E-V-R-G-V-Q-T-D-G-P-I-R-T-L-V-A-K-G-L-V-T-D-K-G-R-V-D-G-A-G-R-A-K-L-Y-V-T-T-S-E-F-L-D-A-F-G-L-N-S-L-E-D-L-P-K-L-A-D-P-A-T-D-E-P-D-Q-N-E-M-D-L-F-F-D-R-F-N-Q-S-K-E-Q-E-E-E"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-H-I-A-L-I-A-H-D-E-K-K-D-L-M-V-G-F-A-T-A-Y-K-H-L-L-E-P-H-Q-L-Y-A-T-G-T-T-G-L-R-I-I-E-A-T-G-L-T-V-H-R-F-K-S-G-P-L-G-G-D-Q-Q-I-G-A-R-I-S-E-N-K-M-D-L-V-I-F-L-R-D-P-L-T-A-Q-P-H-E-P-D-V-T-A-L-I-R-L-C-D-V-Y-E-I-P-L-A-T-N-I-G-T-A-E-I-L-I-R-G-L-G-A-G-F-L-D-W-R-D-L-R-R-N-D-E"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-V-A-K-H-E-R-Q-Q-A-L-V-E-Q-Y-A-E-L-R-R-T-L-K-A-E-G-R-Y-D-E-L-R-K-L-P-R-D-S-S-P-S-R-L-H-N-R-C-E-L-T-G-R-P-H-G-Y-M-R-K-F-G-M-S-R-I-R-F-R-E-L-A-H-Q-G-Q-L-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-T-K-E-S-L-E-K-A-T-F-A-G-G-C-F-W-C-M-V-K-P-F-D-T-Q-P-G-I-E-K-V-V-S-G-Y-T-G-G-H-T-V-N-P-T-Y-K-E-V-C-S-G-T-T-G-H-T-E-A-I-Q-I-T-F-D-P-A-V-F-P-Y-E-K-L-V-E-V-Y-W-Q-Q-T-D-P-T-D-A-A-G-Q-F-V-D-R-G-D-S-Y-R-P-V-I-F-Y-H-N-E-E-Q-K-E-I-A-E-K-S-K-A-A-L-D-A-S-G-R-F-K-K-P-I-V-T-E-I-A-K-A-E-T-F-Y-P-A-E-E-Y-H-Q-D-F-Y-K-K-E-K-A-H-Y-E-G-Y-Q-V-A-S-G-R-A-A-F-I-D-A-N-W-K-G"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-Q-K-Q-V-V-V-M-D-E-A-A-I-K-R-A-L-T-R-V-S-Y-E-I-I-E-R-N-K-G-T-K-N-L-A-L-V-G-I-K-T-R-G-I-Y-L-A-E-R-L-H-K-R-I-L-E-I-E-G-I-D-V-P-V-G-D-I-D-I-T-L-Y-R-D-D-L-S-F-K-D-D-K-T-R-E-P-A-V-H-G-T-N-I-P-F-D-I-N-G-K-K-V-V-L-V-D-D-V-L-Y-T-G-R-T-V-R-A-A-M-D-A-L-M-D-V-G-R-P-A-Q-I-H-L-A-V-L-A-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-G-N-E-R-V-E-V-R-L-T-D-V-D-H-A-E-D-A-V-I-I-N-K-N-E"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-L-Y-P-S-I-D-N-L-L-L-K-I-D-S-K-Y-S-L-V-T-V-A-A-K-R-A-R-Y-M-Q-L-E-N-D-K-G-V-L-P-S-Y-Q-S-D-K-F-V-G-K-A-L-E-E-I-H-A-G-K-L-V-L-Q-N-D-D-K"} +{"text": "### FUNCTION Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism ### SEQUENCE -M-K-K-Y-S-K-K-D-R-Q-M-K-L-Q-V-A-I-E-E-N-P-F-I-T-D-E-Q-L-A-E-K-F-G-V-S-V-Q-T-I-R-L-D-R-V-A-L-S-I-P-E-L-R-E-R-I-K-H-V-A-S-V-N-Y-A-D-A-V-K-S-L-P-I-D-E-V-I-G-E-I-I-D-I-Q-L-S-K-S-A-I-S-I-F-D-V-R-S-E-H-V-F-K-R-N-K-I-A-R-G-H-H-L-F-A-Q-A-N-S-L-A-T-A-V-I-P-N-E-I-A-L-T-T-Q-A-T-V-R-F-V-R-S-V-N-E-G-E-R-I-I-A-K-A-K-V-R-P-A-T-D-N-R-A-I-T-I-V-D-V-K-S-Y-V-G-D-E-I-V-L-K-G-K-F-E-M-Y-H-A-T-Q-K"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-K-M-Y-N-V-G-K-I-V-N-T-H-G-L-I-G-E-I-R-V-I-A-T-T-D-F-P-E-E-R-F-Q-V-G-N-T-V-Y-L-F-E-K-N-S-K-K-P-E-K-L-I-I-R-S-H-R-K-H-K-N-F-D-L-L-M-F-E-G-F-T-G-I-H-Q-V-E-R-M-K-E-G-V-L-K-I-K-E-T-Q-L-T-N-L-E-E-N-E-F-Y-F-H-E-I-I-G-C-T-V-V-T-T-D-G-E-E-L-G-E-I-T-E-I-L-T-P-G-A-N-D-V-W-V-V-K-G-A-D-K-K-E-K-L-I-P-Y-I-A-D-V-V-K-E-I-N-I-D-D-Q-K-I-T-I-E-V-M-E-G-L-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-L-I-G-G-I-R-L-Y-Q-K-Y-I-S-R-F-T-P-A-T-C-R-F-Y-P-T-C-S-A-Y-G-I-E-A-I-Q-T-H-G-A-L-K-G-S-Y-L-A-I-R-R-I-S-K-C-H-P-F-H-K-G-G-L-D-F-V-P-P-K-K-D-K-N-A-D-S-E-H-S-C-K-V-H-H-H-H"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-T-C-Q-Y-N-G-T-R-V-V-D-S-R-P-A-D-D-G-N-S-I-R-R-R-R-E-C-E-K-C-G-F-R-F-T-T-F-E-K-V-E-E-S-P-L-I-V-V-K-K-D-G-A-R-E-E-F-A-R-E-K-V-R-R-G-L-I-R-A-C-E-K-R-P-V-S-A-E-Q-I-E-E-I-V-N-E-V-E-R-E-L-R-N-I-G-D-S-E-I-A-S-D-L-I-G-E-K-V-M-N-K-L-A-N-L-D-E-V-A-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-I-S-V-F-V-E-E-L-K-D-L-M-E-K-N-K-D-R"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-D-V-N-N-V-E-L-I-I-S-A-V-R-P-E-Q-Y-P-E-T-D-L-P-E-Y-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-M-I-R-R-K-S-M-A-R-I-S-Q-K-P-G-K-T-Q-T-L-N-F-Y-K-I-E-E-A-L-F-F-V-D-V-P-G-Y-G-F-A-K-V-S-K-T-E-R-E-K-W-G-V-M-I-E-T-Y-I-T-S-R-E-Q-L-R-G-V-I-Q-I-V-D-L-R-H-K-P-T-E-D-D-R-M-M-Y-E-F-L-K-Y-Y-D-I-P-V-I-V-I-A-T-K-A-D-K-I-P-R-S-K-W-Q-K-N-A-K-I-V-R-E-T-L-D-F-D-P-D-D-K-F-V-L-F-S-S-E-T-K-M-G-K-D-E-A-W-Q-F-I-K-E-G-M-E"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-E-T-G-G-K-Q-I-K-V-E-A-G-Q-E-I-Y-V-E-K-L-A-G-E-V-G-D-V-V-T-F-D-K-V-L-F-V-G-G-D-S-A-K-V-G-V-P-F-V-E-G-A-T-V-T-A-K-V-E-K-Q-G-R-A-K-K-L-T-V-Y-K-Y-K-P-K-K-N-Y-H-K-K-Q-G-H-R-Q-P-Y-T-K-L-T-I-D-A-I-N-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-M-G-L-D-V-G-S-K-T-V-G-V-A-I-S-D-P-L-G-W-T-A-Q-G-V-E-T-I-Q-I-D-E-N-R-K-Q-F-G-Y-D-R-V-K-E-L-V-L-E-Y-E-V-E-K-V-V-V-G-L-P-K-N-M-N-N-T-I-G-P-R-A-E-S-S-K-I-Y-A-E-V-L-E-A-R-I-G-L-P-V-V-L-W-D-E-R-L-T-T-S-A-A-E-R-T-L-I-E-A-D-V-S-R-K-K-R-K-E-V-I-D-K-L-A-A-V-M-I-L-Q-S-Y-L-D-T-T-N"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-K-H-K-V-G-I-L-G-G-T-F-D-P-P-H-L-A-H-L-H-M-A-E-E-A-K-K-Q-L-E-L-E-K-I-L-F-L-P-N-K-I-P-P-H-K-H-I-S-G-M-A-S-I-N-E-R-V-E-M-L-Q-L-M-I-E-G-I-D-S-F-E-I-D-T-R-E-L-M-R-T-G-K-S-Y-T-Y-D-T-M-R-D-M-I-I-E-Q-P-D-T-D-F-Y-F-I-I-G-G-D-M-V-E-Y-L-P-K-W-Y-H-I-D-D-L-V-K-M-V-T-F-V-G-V-N-R-P-L-Y-Q-P-E-V-P-Y-D-V-V-K-I-D-M-P-K-T-T-I-S-S-T-E-I-R-N-D-I-E-H-A-E-A-F-L-P-E-K-V-W-S-Y-I-K-E-H-Q-L-Y-G-K-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-V-L-E-I-D-L-L-D-E-T-K-N-L-L-D-E-D-K-Q-L-V-E-N-I-L-Q-F-A-A-E-Y-L-K-I-E-Q-G-T-E-L-S-L-T-F-T-T-N-E-G-I-R-E-I-N-R-E-Y-R-D-K-D-Q-A-T-D-V-I-S-F-A-L-E-E-M-G-D-G-E-T-E-I-D-W-G-E-F-D-L-E-T-P-R-M-L-G-D-I-I-I-S-T-E-K-A-E-E-Q-A-K-D-Y-G-H-T-K-A-R-E-L-G-F-L-A-V-H-G-L-L-H-L-L-G-Y-D-H-M-E-P-D-E-E-K-V-M-F-G-L-Q-K-E-V-L-D-A-Y-G-L-E-R"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-G-H-R-H-I-I-I-R-E-L-I-T-S-N-E-I-D-T-Q-E-D-L-V-E-L-L-L-E-R-D-V-K-V-T-Q-A-T-V-S-R-D-I-K-E-L-H-L-V-K-V-P-T-Q-T-G-G-Y-K-Y-S-L-P-A-D-N-S-F-N-P-H-Q-K-L-K-R-A-L-I-D-C-F-I-G-I-D-N-V-Q-F-M-I-I-L-K-V-M-P-G-N-G-N-S-V-G-A-L-I-D-N-L-D-W-P-E-K-A-G-T-I-C-G-D-D-T-C-L-I-I-C-R-S-E-E-N-A-K-T-L-T-D-R-F-I-D-M-L"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-T-K-K-K-T-F-E-E-A-I-A-E-L-E-T-I-V-E-A-L-E-N-G-S-A-S-L-E-D-S-L-D-M-Y-Q-K-G-I-E-L-T-K-L-C-Q-D-K-L-Q-S-A-E-K-R-M-A-K-V-V-T-D-A-G-E-E-I-P-F-E-A-D-G-E"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-R-R-E-A-R-E-K-A-L-Q-A-L-F-Q-I-E-L-N-E-M-S-L-D-Q-A-I-K-N-I-M-E-D-E-Q-D-D-Y-M-E-K-L-V-E-G-V-M-A-N-K-A-E-I-D-A-I-I-E-P-N-L-D-N-W-R-M-D-R-L-S-K-V-D-L-S-L-L-R-L-S-V-Y-E-I-K-Y-L-D-D-V-P-N-R-V-S-L-N-E-S-I-E-I-A-K-I-Y-S-D-E-K-S-S-K-F-I-N-G-V-L-A-N-I-A-P-E-D-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-N-V-R-A-N-R-V-S-E-Q-M-K-K-E-L-G-D-I-L-N-R-K-I-K-D-P-R-L-G-F-V-T-V-T-G-V-D-V-T-G-D-L-Q-E-A-K-V-F-I-S-I-L-G-T-D-K-E-K-E-N-T-L-L-A-L-A-K-A-H-G-F-I-R-S-E-I-G-R-R-I-R-L-R-K-V-P-E-M-S-F-E-I-D-N-S-I-A-Y-G-N-R-I-D-E-L-L-R-D-L-N-N-D-Q"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-K-V-L-E-Q-V-E-A-I-V-A-P-I-T-D-E-L-Q-L-E-L-V-D-I-A-F-E-K-E-G-P-N-W-F-L-R-I-F-I-D-K-D-G-G-V-D-I-D-E-C-A-A-V-S-E-K-V-S-E-K-M-D-E-N-D-P-I-T-Q-N-Y-F-L-E-V-S-S-P-G-A-E-R-P-L-K-K-E-Q-D-F-E-N-A-V-S-K-Y-V-H-V-T-S-Y-E-P-I-D-G-R-K-M-W-E-G-T-L-V-S-Y-D-G-T-T-L-V-I-T-I-T-D-K-T-R-K-I-T-C-E-I-P-K-D-K-V-A-K-A-R-L-A-I-Q-F"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-K-E-V-L-S-K-S-K-E-K-M-E-K-A-E-Q-A-L-T-R-Q-L-G-T-I-R-A-G-R-A-N-A-S-L-L-D-R-L-S-V-D-Y-Y-G-A-A-T-P-V-N-Q-M-A-S-I-S-V-P-E-A-R-M-L-L-I-T-P-Y-D-K-T-I-L-G-E-I-E-K-A-I-L-K-S-D-L-G-L-T-P-N-N-D-G-S-V-L-R-L-S-I-P-Q-L-T-E-E-R-R-K-E-L-V-K-E-V-K-K-E-A-E-E-A-K-V-A-V-R-N-I-R-R-E-A-N-E-E-L-K-K-L-E-K-N-G-D-I-T-E-D-D-L-R-S-Y-G-E-D-V-Q-K-L-T-D-E-S-I-K-N-I-D-S-I-T-K-D-K-E-A-E-I-L-E-V"} +{"text": "### FUNCTION Inhibits cell division during the SOS response Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and/or DivIC to the division machinery ### SEQUENCE -M-T-L-K-L-I-W-D-K-F-Y-V-S-I-I-F-V-L-T-C-I-V-L-G-I-I-L-M-C-T-V-V-G-G-G-S-D-Y-S-E-V-N-V-N-E-G-D-S-L-W-A-L-A-D-Q-Y-A-G-K-S-D-M-A-K-A-D-F-V-S-W-V-E-K-E-N-N-L-S-D-G-H-V-E-A-G-D-S-V-V-I-P-V-H-K-T-K-L-L-K-S-D-S-T-I-Q-L-A-N-Q"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-K-G-I-G-L-D-M-I-D-L-E-R-V-K-Q-V-V-E-K-N-P-R-F-I-E-R-V-L-T-E-K-E-I-K-Q-F-E-K-Y-E-G-N-R-K-I-E-F-L-A-G-R-F-A-A-K-E-A-Y-A-K-A-N-G-T-G-F-G-K-H-L-S-F-T-D-V-E-I-L-Q-V-E-D-G-R-P-H-V-T-L-P-V-K-S-G-E-N-V-F-V-S-I-T-H-T-A-R-S-A-A-A-Q-V-I-I-E-I"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-N-I-Q-I-V-T-V-G-K-L-K-E-K-Y-L-V-Q-G-I-A-E-Y-L-K-R-L-S-A-Y-A-K-V-T-I-V-E-V-P-D-E-K-A-P-E-V-L-S-D-A-E-M-K-Q-V-K-D-K-E-G-A-R-I-L-A-K-I-P-D-D-A-Y-V-I-A-L-A-I-D-G-K-M-K-S-S-E-E-F-A-A-D-L-D-K-L-A-T-Y-G-K-S-K-V-T-F-V-I-G-G-S-L-G-L-S-E-A-V-L-K-R-S-N-E-R-I-S-F-G-R-L-T-L-P-H-Q-L-M-R-L-V-L-V-E-Q-V-Y-R-A-F-R-I-V-R-G-E-P-Y-H-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-N-I-E-E-I-I-A-S-V-K-E-A-S-V-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-V-A-A-A-G-G-A-A-A-E-Q-T-E-F-T-V-E-L-A-S-A-G-D-S-K-I-K-V-I-K-V-V-R-E-I-T-G-L-G-L-K-E-A-K-E-L-V-D-N-A-P-K-A-L-K-E-G-I-A-K-D-E-A-E-E-I-K-A-K-L-E-E-V-G-A-N-V-E-V-K"} +{"text": "### FUNCTION Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 ### SEQUENCE -M-A-E-V-K-E-Y-K-Q-L-N-G-L-A-L-A-Y-M-G-D-A-V-Y-E-K-F-I-R-E-Y-L-L-A-A-G-K-T-K-P-N-Q-L-H-K-T-A-T-K-F-V-S-A-K-G-Q-A-V-A-L-K-A-M-I-A-E-G-F-L-T-E-E-E-D-R-I-A-K-R-G-R-N-A-K-S-Y-T-V-P-K-N-T-D-P-G-T-Y-S-M-S-T-S-F-E-A-V-L-G-Y-L-Y-L-A-G-E-M-E-R-L-Q-E-W-M-E-K-A-L-E-I-V-E-K-G-V-E-T-N"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-A-G-L-G-N-P-G-K-K-Y-E-R-T-R-H-N-V-G-F-M-V-V-D-E-L-S-F-R-H-Q-T-P-W-K-K-S-K-F-N-G-M-T-S-E-I-I-V-G-G-E-K-M-I-L-V-K-P-L-T-F-M-N-A-S-G-E-C-I-R-P-L-M-D-Y-Y-N-I-P-I-E-D-V-V-I-V-Y-D-D-L-D-L-P-V-G-K-I-R-L-R-Q-K-G-S-A-G-G-H-N-G-M-K-S-I-I-Q-H-V-K-T-Q-E-F-N-R-I-R-V-G-V-S-R-P-L-K-G-E-V-I-N-Y-V-L-G-D-F-P-K-A-E-Q-P-D-I-I-A-A-I-Q-K-S-A-D-A-I-E-D-F-A-Q-T-P-F-I-E-V-M-N-K-Y-N-Q-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-I-T-D-V-R-L-R-R-V-E-T-D-G-R-M-K-A-I-S-S-I-T-I-D-G-E-F-V-I-H-D-I-R-V-I-D-G-N-E-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-G-T-R-A-K-I-Q-E-A-V-L-A-A-Y-E-V-A-D-E-P-A-V-N-E-E-S-S-A-D-E-S-I-V-E-E-N"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-A-I-F-D-S-V-S-N-M-E-E-Q-I-G-E-L-Y-Q-Q-L-G-D-L-K-T-N-L-G-E-M-L-E-E-N-N-R-L-N-L-E-N-E-H-L-R-R-R-L-S-L-T-D-E-A-T-P-E-P-K-A-E-T-E-A-E-H-G-V-M-A-P-N-R-K-E-A-M-Q-Q-M-I-E-L-G-E-G-Y-D-N-L-V-Q-L-Y-K-E-G-F-H-V-C-N-V-H-F-G-S-P-R-G-N-D-E-D-C-L-F-C-L-S-L-L-N-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-K-D-V-K-G-K-G-K-K-G-E-T-K-N-V-A-D-G-Y-A-N-N-F-L-I-K-N-G-Y-A-V-E-A-N-N-A-A-L-S-T-L-S-A-Q-K-K-K-E-D-K-L-A-A-E-E-L-A-E-A-K-A-L-K-E-K-M-E-N-L-T-V-E-L-K-A-K-S-G-E-G-G-R-L-F-G-S-I-T-S-K-Q-I-A-Q-T-L-E-K-T-H-G-I-K-I-D-K-R-K-M-D-L-P-E-A-I-R-A-L-G-H-T-K-V-P-V-K-L-H-H-E-V-T-A-T-L-D-V-H-V-S-E-E"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-M-N-R-V-V-L-V-G-R-L-T-K-D-P-E-L-R-Y-T-P-A-G-V-A-V-A-T-F-T-L-A-V-N-R-T-F-T-N-Q-Q-G-E-R-E-A-D-F-I-N-C-V-V-W-R-K-P-A-E-N-V-A-N-F-L-K-K-G-S-M-A-G-V-D-G-R-V-Q-T-R-N-Y-E-G-N-D-G-K-R-V-Y-V-T-E-I-V-A-E-S-V-Q-F-L-E-P-R-N-S-N-G-G-G-G-N-N-Y-Q-S-G-N-N-N-N-N-Y-N-S-G-G-N-N-F-G-Q-A-P-T-N-N-G-G-F-G-Q-D-Q-Q-Q-S-Q-N-Q-N-Y-Q-S-T-N-N-D-P-F-A-S-D-G-K-P-I-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-R-K-Y-E-I-M-Y-I-I-R-P-N-I-E-E-D-E-K-K-A-V-V-E-R-F-D-G-I-L-T-E-N-G-A-E-I-I-E-S-K-E-W-G-K-R-R-L-A-Y-E-I-N-D-Y-R-D-G-F-Y-H-I-V-K-L-N-A-D-K-A-D-S-I-N-E-F-D-R-L-A-K-I-S-D-D-I-I-R-H-M-V-I-K-E-E-A"} +{"text": "### FUNCTION Required for optimal acid stress protection Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins ### SEQUENCE -M-I-K-A-L-F-N-K-N-T-A-L-A-A-V-A-I-L-A-L-S-G-G-A-M-A-E-S-A-K-T-H-K-T-D-M-A-K-K-K-V-S-E-L-T-C-E-D-F-N-G-L-E-E-S-F-K-P-T-V-V-G-W-V-V-G-F-N-K-K-G-K-E-E-D-A-V-I-D-V-D-G-I-E-T-V-T-P-A-I-I-E-A-C-K-Q-E-P-K-A-S-F-W-K-K-A-E-A-E-L-K-K-V-F"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-T-A-E-I-E-E-I-P-A-L-L-K-P-G-Q-T-V-A-G-L-D-L-G-T-K-T-I-G-L-A-V-S-D-L-G-L-S-F-A-H-P-R-P-V-I-K-R-V-K-F-T-I-D-A-Q-V-L-L-K-A-L-E-T-D-K-V-G-V-I-V-I-G-L-P-M-N-M-D-G-T-A-G-P-R-V-Q-A-T-R-A-F-V-R-T-M-Q-P-L-T-D-L-P-F-V-F-W-D-E-R-L-S-T-V-A-V-E-R-A-L-I-G-M-D-V-S-R-G-K-R-A-D-R-I-D-S-A-A-A-A-F-I-L-Q-G-A-L-D-R-L-H-M-M-R-R-N-D-Y-D-A-G"} +{"text": "### FUNCTION Essential protein that is involved in the control of cell division, probably through the regulation of ctrA Its phosphorylation status is regulated by PdhS ### SEQUENCE -M-T-K-S-V-M-I-V-E-D-N-E-L-N-M-K-L-F-R-D-L-I-E-A-S-G-Y-E-T-I-R-T-R-S-G-L-E-A-L-D-L-A-R-E-H-H-P-D-L-I-L-M-D-I-Q-L-P-E-V-S-G-L-E-V-T-K-W-L-K-D-D-E-E-L-R-H-I-P-V-I-A-V-T-A-F-A-M-K-G-D-E-E-R-I-R-Q-G-G-C-E-A-Y-I-S-K-P-I-S-V-P-R-F-I-E-T-I-K-S-Y-L-G-D-A"} +{"text": "### FUNCTION Antioxidant protein with alkyl hydroperoxidase activity Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity ### SEQUENCE -M-S-I-D-D-L-K-S-K-I-P-D-F-A-K-D-V-R-L-N-L-S-S-M-A-S-D-E-T-L-T-P-Q-Q-K-Y-G-L-F-V-A-C-G-I-A-S-R-N-A-D-V-R-K-A-L-V-A-E-A-A-G-K-V-D-A-S-V-I-Q-A-A-K-A-A-A-S-I-M-G-M-N-N-V-Y-Y-R-F-V-H-L-A-S-N-K-D-Y-R-T-M-P-A-R-L-R-M-N-V-I-S-N-P-G-V-D-K-V-D-F-E-L-W-S-L-A-V-S-A-I-N-G-C-G-M-C-I-D-A-H-E-D-V-L-R-K-A-N-V-T-A-E-A-I-Q-A-A-V-R-F-A-S-I-I-Q-S-A-A-I-A-L-E-A-A-D-T-E"} +{"text": "### FUNCTION Transcriptional repressor of the nikABCDE operon Is active in the presence of excessive concentrations of intracellular nickel ### SEQUENCE -M-Q-R-I-T-I-T-I-D-D-D-L-M-A-A-L-D-R-M-I-E-I-K-G-Y-Q-N-R-S-E-A-L-R-D-L-A-R-T-G-L-Q-Q-A-S-L-E-E-G-Q-M-E-A-C-V-G-V-L-S-Y-T-Y-D-H-S-A-R-D-L-S-K-K-L-T-N-T-H-H-D-H-H-N-I-S-V-A-S-M-H-V-H-L-D-H-D-R-C-L-E-V-S-I-L-K-S-K-T-D-D-V-R-H-F-A-D-H-V-K-A-E-R-H-V-T-H-G-T-L-A-V-L-P-L"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-R-F-F-L-S-G-Y-V-G-R-R-I-G-E-T-F-P-W-G-T-F-V-V-N-V-S-G-A-F-V-I-G-T-A-A-G-L-G-A-R-L-G-G-I-F-S-T-T-I-F-H-E-F-I-M-V-G-L-L-G-G-Y-T-T-V-S-S-F-C-L-Q-S-V-N-L-M-L-D-G-E-Q-R-Q-A-L-F-N-I-V-A-S-A-L-L-C-V-L-A-V-A-A-G-Y-G-G-I-M-W-I-M-E-W-P-G"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-R-N-W-R-Q-A-E-N-I-R-L-Y-I-A-V-G-C-G-A-A-I-G-A-L-L-R-F-L-S-G-W-V-I-V-A-I-L-G-A-N-P-L-W-G-T-S-F-V-N-I-V-G-S-F-I-I-M-F-F-A-T-L-T-G-P-E-G-R-W-L-V-S-P-A-L-R-Q-F-V-M-G-G-L-C-G-G-L-T-T-F-S-S-M-S-L-D-T-F-L-L-V-L-H-G-N-A-A-F-A-L-A-Y-L-C-G-L-V-F-L-S-L-S-A-A-M-L-G-L-I-A-A-Q-R-I-N-R"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-S-K-K-Q-I-L-R-L-R-K-R-A-E-F-L-T-V-R-N-G-E-K-R-R-G-P-L-F-L-M-A-V-R-E-R-T-E-E-E-S-N-A-A-K-T-G-D-N-P-R-V-G-F-T-V-T-K-K-N-G-N-A-V-I-R-N-R-I-R-R-R-L-K-E-A-I-R-C-H-A-G-R-D-M-A-P-S-T-D-Y-V-I-V-A-R-E-Q-A-L-N-A-P-F-S-Q-L-T-E-E-L-S-R-R-I-T-A-K-G-E-R-R-S-G-G-K-R-R-T-E-R-P-E-P-G-P-V-N-G-K"} +{"text": "### FUNCTION Has a post-transcriptional repressor function in flagellum biogenesis Associates with the 5'-UTR of fljK mRNA and promotes its degradation ### SEQUENCE -M-A-A-N-S-K-T-A-I-R-L-S-L-R-A-G-E-R-I-F-I-N-G-A-V-L-R-A-D-R-K-V-S-L-E-L-L-N-D-A-T-F-L-L-E-N-H-V-L-Q-P-E-D-T-T-T-P-L-R-Q-L-Y-F-A-A-Q-M-M-L-I-E-P-A-M-R-E-Q-A-G-A-T-F-A-Q-M-L-K-G-M-F-A-T-F-K-D-A-E-I-L-N-A-L-K-L-V-D-E-L-V-H-N-G-R-V-F-E-A-L-K-T-I-R-A-Q-Y-P-R-E-A-E-L-M-G-A-Q-P-V-V-W-P-V-T-K-S-G-K-S-A-G-A-N-P"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-T-V-K-L-V-L-A-S-K-S-P-F-R-S-A-L-L-K-N-A-G-I-E-F-S-T-A-S-A-D-I-D-E-R-A-V-E-A-P-L-Y-E-S-G-A-T-P-E-D-V-A-Q-I-L-A-E-A-K-A-I-D-V-S-E-K-N-P-G-A-V-V-I-G-C-D-Q-T-L-S-L-G-D-E-I-F-H-K-P-H-D-M-E-A-A-R-R-Q-L-Q-K-F-S-G-K-T-H-Q-L-N-S-A-V-V-L-A-R-D-G-K-T-L-W-R-H-V-S-I-A-H-M-T-M-R-D-L-D-A-G-F-I-G-R-Y-L-G-R-V-G-D-I-A-L-S-N-V-G-A-Y-Q-V-E-G-P-G-I-Q-L-F-E-K-I-D-G-D-Y-F-T-I-V-G-L-P-L-L-P-L-L-A-E-L-R-R-E-K-C-I-D-G"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-D-K-A-A-G-E-T-K-N-G-N-G-A-T-T-E-P-S-L-N-I-L-A-Q-Y-V-K-D-L-S-F-E-S-P-G-A-P-L-S-L-R-P-R-E-K-A-P-S-I-N-I-N-V-N-V-N-A-N-P-L-S-E-T-D-F-D-V-V-L-T-L-E-A-K-A-V-D-G-K-D-I-L-F-N-T-E-L-V-Y-G-G-V-F-R-I-Q-G-I-P-Q-E-H-M-L-P-L-L-F-I-E-C-P-R-L-L-F-P-F-A-R-Q-I-I-A-D-A-T-R-N-G-G-Y-P-P-L-M-I-D-P-I-D-F-A-Q-M-F-Q-Q-R-M-A-E-E-Q-A-K-S-A-V-K-S"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-R-S-H-D-T-K-G-S-G-G-L-S-Q-R-Q-L-R-V-G-E-Q-V-R-H-A-L-A-Q-V-L-Q-R-G-E-I-R-D-D-L-I-E-R-T-V-I-S-V-S-E-V-R-M-S-P-D-L-K-I-A-T-C-F-I-T-P-L-G-S-A-D-P-Q-A-V-I-K-A-L-A-S-H-A-K-F-I-R-G-R-V-A-P-S-L-A-Q-M-K-Y-M-P-E-F-R-F-R-P-D-T-S-F-D-N-F-S-K-I-D-A-L-L-R-F-P-E-V-A-R-D-L-S-H-D-D-D-E-D-G-G-A-D-E-A-P-R-N-G-D-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-I-T-A-E-R-K-Q-A-L-I-K-E-Y-A-T-K-E-G-D-T-G-S-P-E-V-Q-V-A-V-L-S-E-R-I-A-N-L-T-E-H-F-K-G-H-K-N-D-N-H-S-R-R-G-L-L-K-L-V-S-Q-R-R-R-L-L-D-Y-V-K-G-V-D-H-A-R-Y-Q-A-L-I-T-R-L-G-L-R-R"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-I-K-S-E-L-V-Q-I-I-A-S-R-N-P-H-L-F-Q-R-D-V-V-N-I-V-G-A-V-F-D-E-I-T-N-A-L-A-E-G-N-R-V-E-L-R-G-F-G-A-F-S-V-K-N-R-P-A-R-S-G-R-N-P-R-T-G-E-T-V-D-V-E-E-K-W-V-P-F-F-K-T-G-K-K-L-R-D-R-L-N-G-A-V"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-Q-E-F-A-L-K-G-N-M-V-D-L-A-I-G-V-I-I-G-G-A-F-G-G-L-V-N-S-I-V-N-D-I-I-M-P-I-I-G-L-I-T-G-G-I-D-F-S-N-M-F-I-Q-L-A-G-D-P-K-T-T-L-A-A-A-R-E-A-G-A-T-I-A-Y-G-N-F-I-T-L-L-I-N-F-L-I-I-A-W-V-L-F-L-V-V-K-L-M-N-R-L-K-K-R-E-E-A-K-P-A-P-A-A-P-S-E-E-V-L-L-T-E-I-R-D-I-L-A-K-Q-Q-K-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-V-I-L-L-E-R-I-G-R-L-G-Q-M-G-D-T-V-K-V-K-D-G-Y-A-R-N-F-L-L-P-Q-G-K-A-L-R-A-N-E-A-N-K-K-K-F-E-G-Q-R-A-Q-L-E-A-Q-N-L-E-R-K-N-E-A-Q-A-V-A-D-K-L-N-G-E-S-F-I-V-V-R-S-A-G-E-T-G-Q-L-Y-G-S-V-S-T-R-D-I-A-E-I-I-T-A-N-G-F-T-L-H-R-N-Q-V-E-L-N-H-P-I-K-T-I-G-L-H-E-V-S-V-S-L-H-P-E-V-Q-V-K-V-M-V-N-I-A-R-S-T-E-E-A-E-C-Q-A-K-G-E-D-L-T-S-I-E-A-I-Y-G-I-E-E-Q-P-L-S-E-E-V-F-D-D-E-D-E-A-E-D-Q-A"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-L-Y-E-H-V-L-L-A-R-Q-D-I-S-Q-Q-Q-V-D-A-L-V-E-Q-F-K-G-V-L-E-A-N-G-G-K-F-G-K-V-E-N-W-G-L-R-P-L-T-Y-R-I-K-K-N-R-K-A-Y-Y-T-L-V-N-I-D-A-P-A-A-A-V-A-E-M-E-R-Q-M-R-I-N-E-D-V-L-S-F-L-T-V-R-V-E-E-H-E-E-G-Q-S-A-M-L-T-R-R-D-D-R-R-E-R-D-G-D-D-R-P-R-R-R-E-G-G-F-D-R-G-D-R-G-D-R-G-P-R-R-P-R-D-N-E-A-G-E-G-A"} +{"text": "### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate -ureidoglycolate, generating urea and glyoxylate Involved in the utilization of allantoin as nitrogen source ### SEQUENCE -M-Q-I-E-T-L-T-V-E-P-L-T-K-E-A-F-A-P-F-G-D-V-I-E-V-E-G-A-Q-L-R-L-I-N-N-G-T-T-E-R-Y-H-D-L-A-R-V-E-A-A-G-T-Q-T-R-A-L-I-N-I-F-R-G-Q-S-F-A-A-P-I-D-I-M-M-M-E-R-H-P-F-G-S-Q-A-F-I-P-L-N-G-R-P-F-L-V-V-V-A-E-D-A-G-A-G-P-A-R-P-R-A-F-L-A-R-G-D-Q-G-V-N-Y-L-R-N-I-W-H-H-P-L-L-A-L-E-Q-K-S-D-F-L-V-V-D-R-A-G-R-E-D-N-L-E-E-Y-F-F-S-D-Y-A-Y-R-I-E-T-T-Q-T-A"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 5-hydroxyisourate ### SEQUENCE -M-G-K-L-S-T-H-V-L-D-T-A-H-G-T-P-A-A-A-M-R-V-E-L-Y-R-I-A-A-S-G-T-P-E-L-L-K-R-V-V-T-N-L-D-G-R-T-D-A-P-L-L-S-G-D-E-M-R-T-G-I-Y-E-L-Q-F-H-V-A-E-Y-F-E-G-R-G-A-E-L-A-H-E-P-F-L-D-L-I-P-I-R-F-G-I-A-D-E-D-G-N-Y-H-V-P-L-L-V-S-P-W-S-Y-S-T-Y-R-G-S"} +{"text": "### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-I-G-M-E-P-L-R-R-R-E-L-I-D-A-A-I-R-T-I-G-Q-R-G-S-L-D-V-T-V-A-Q-I-A-H-E-A-G-V-S-P-A-L-A-H-H-Y-F-G-G-K-D-K-L-I-L-A-T-M-R-H-L-L-R-E-L-G-R-D-L-N-A-A-I-K-Q-A-N-T-P-H-E-R-I-A-A-I-I-A-V-N-F-S-A-T-Q-F-A-Q-E-T-I-A-A-W-L-T-F-Y-V-H-A-Q-Q-S-D-D-I-K-R-L-L-R-I-Y-A-R-R-L-H-S-N-L-V-F-A-L-E-Q-L-T-S-R-A-R-A-N-R-I-A-E-G-A-G-A-M-I-D-G-L-Y-I-R-H-A-L-G-A-D-A-P-D-A-A-S-A-I-A-L-V-E-D-Y-I-A-I-Q-L-S-G-Q-P-S-A-E-N"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-C-V-D-K-V-E-N-R-F-E-L-V-L-L-A-G-H-R-A-R-Q-I-S-Q-G-A-P-I-T-V-D-R-D-N-D-K-N-P-V-V-A-L-R-E-I-A-D-E-T-L-S-P-D-D-L-K-E-D-L-I-H-S-L-Q-K-H-V-E-V-D-E-P-E-A-A-P-A-Q-I-A-N-A-A-E-E-I-A-E-G-I-A-E-A-G-E-E-D-V-V-T-F-D-R-M-S-E-E-E-L-L-A-G-I-E-G-L-V-A-P-E-K-N-D-G-F"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-N-S-I-P-E-G-R-P-T-P-N-L-Q-R-T-A-N-K-R-G-V-A-R-L-A-A-V-Q-A-L-F-Q-M-D-V-A-G-T-G-V-M-E-V-V-A-E-Y-E-A-F-R-L-G-K-E-V-D-G-T-Q-Y-L-D-A-D-P-Q-W-F-R-A-I-V-A-G-V-V-E-D-Q-L-K-L-D-P-M-I-H-Q-A-L-T-E-D-W-P-L-S-R-L-D-S-T-L-R-A-I-L-R-A-G-A-W-E-L-K-A-R-K-D-V-P-T-A-V-I-V-S-E-Y-V-D-I-A-K-A-F-Y-T-E-D-E-P-K-L-V-N-A-V-L-D-R-L-A-L-V-I-R-G-E-S-R-G-A-K-P-R-H-K-S"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-A-T-F-S-Q-K-P-A-E-V-V-K-K-W-V-L-I-D-A-E-G-L-V-V-G-R-L-A-S-L-V-A-N-R-L-R-G-K-H-K-A-T-F-T-P-H-V-D-D-G-D-N-V-I-I-I-N-A-D-K-V-V-L-T-G-K-K-Y-T-D-K-K-Y-Y-W-H-T-G-H-P-G-G-I-K-E-R-T-A-R-Q-I-L-E-G-R-F-P-E-R-V-L-E-K-A-I-E-R-M-I-P-R-G-P-L-G-R-R-Q-M-K-N-L-R-V-N-A-G-P-N-H-Q-H-E-A-Q-Q-P-E-V-L-D-V-A-A-L-N-R-K-N-K-G-N-A"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-V-N-K-V-I-L-V-G-N-L-G-A-D-P-E-I-R-R-L-N-S-G-D-M-V-A-N-L-R-I-A-T-S-E-S-W-R-D-R-Q-T-G-E-R-K-D-R-T-E-W-H-S-V-V-I-F-N-E-N-L-A-K-V-A-E-Q-Y-L-K-K-G-A-K-V-Y-I-E-G-A-L-Q-T-R-K-W-Q-D-Q-N-G-N-D-R-Y-S-T-E-I-V-L-Q-K-F-R-G-E-L-Q-M-L-D-S-R-S-E-G-S-E-G-R-S-F-G-G-G-G-N-R-N-Q-M-S-D-Y-S-G-G-G-G-D-F-G-S-S-G-P-S-S-G-S-S-G-G-F-S-R-D-L-D-D-E-I-P-F"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-R-R-F-N-T-I-M-Q-G-K-T-N-G-G-N-G-P-E-S-G-T-V-V-V-T-R-T-Q-P-K-T-R-K-P-S-L-Y-R-V-L-L-L-N-D-D-Y-T-P-M-E-F-V-V-H-V-L-Q-R-F-F-Q-K-N-L-D-D-A-T-R-I-M-L-H-V-H-N-H-G-V-G-E-C-G-V-F-T-Y-E-V-A-E-T-K-V-S-Q-V-M-D-F-A-R-Q-N-Q-H-P-L-Q-C-V-M-E-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-D-L-R-D-K-P-G-S-V-K-A-R-K-R-V-G-R-G-I-G-S-G-T-G-K-T-G-G-R-G-V-K-G-Q-K-S-R-S-G-V-S-I-N-G-F-E-G-G-Q-M-P-I-Y-R-R-L-P-K-R-G-F-T-N-I-F-A-K-S-F-N-V-V-S-L-G-R-I-Q-A-A-I-D-A-G-K-L-D-A-K-A-V-V-N-L-D-S-L-K-A-A-G-V-I-R-R-A-K-D-G-V-R-I-L-S-D-G-E-L-K-A-K-V-A-F-E-V-A-G-A-S-K-A-A-V-E-K-I-E-K-A-G-G-S-I-K-L-P-E-A-A-A-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-S-P-K-E-T-L-Q-R-R-A-A-R-V-R-R-Q-V-K-A-V-A-N-G-R-P-R-L-S-V-H-R-S-S-K-N-I-Y-A-Q-I-I-D-D-V-R-G-V-T-L-A-A-A-S-T-L-D-G-D-L-K-G-K-L-K-T-G-A-D-S-A-A-A-A-A-V-G-K-L-V-A-E-R-A-V-K-A-G-V-K-D-V-V-F-D-R-G-A-F-I-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-G-G-L-S-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-P-V-P-V-P-A-G-V-T-A-S-V-E-G-Q-T-V-K-A-K-G-A-K-G-E-L-S-F-V-V-H-D-E-V-L-V-K-M-E-D-G-A-V-R-V-D-P-R-D-Q-S-R-E-A-R-S-K-W-G-M-S-R-T-M-I-S-N-I-F-V-G-V-K-D-G-F-E-K-K-L-E-I-S-G-V-G-Y-R-A-A-M-Q-G-K-N-L-Q-L-S-L-G-F-S-H-E-V-V-Y-D-V-P-A-G-I-T-V-A-V-P-K-P-T-E-I-V-V-T-G-I-D-K-Q-Q-V-G-Q-V-A-A-E-I-R-E-Y-R-G-P-E-P-Y-K-G-K-G-V-K-Y-A-G-E-K-I-V-R-K-E-G-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-V-S-D-P-L-G-D-M-L-T-R-I-R-N-A-V-G-R-K-K-T-K-V-S-T-P-A-S-K-L-R-A-R-V-L-D-V-L-Q-A-E-G-Y-I-R-G-Y-T-Q-S-E-F-E-N-G-K-A-E-I-E-I-E-L-K-Y-Y-E-G-V-P-V-I-R-E-I-T-R-V-S-K-P-G-R-R-V-Y-V-S-V-K-S-I-P-Q-V-V-N-G-L-G-I-S-I-L-S-T-P-K-G-V-M-A-D-H-E-A-R-E-Q-N-V-G-G-E-L-L-C-R-I-F"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-E-A-K-A-L-P-R-F-K-K-L-Y-Q-D-N-I-R-K-A-L-L-E-E-F-K-Y-D-N-E-M-Q-I-P-R-I-T-K-V-V-L-N-M-G-V-G-E-A-T-G-D-S-K-K-P-A-V-A-A-E-D-L-A-M-I-A-G-Q-K-A-V-V-T-R-A-R-N-S-I-A-T-F-K-L-R-E-G-M-P-I-G-A-K-V-T-L-R-Q-D-R-M-Y-E-F-L-D-R-L-I-T-I-A-L-P-R-V-R-D-F-R-G-L-N-P-K-S-F-D-G-R-G-N-Y-A-M-G-I-K-E-H-I-V-F-P-E-I-N-Y-D-K-V-D-Q-I-W-G-M-D-I-I-V-C-T-T-A-K-T-D-D-E-A-R-S-L-L-R-A-F-N-F-P-F-R-Q"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-K-I-R-K-G-D-S-V-V-V-L-S-G-K-D-K-G-R-K-G-E-V-L-K-V-M-P-K-D-E-Q-A-L-V-S-G-I-N-I-V-K-R-H-Q-R-Q-T-Q-T-Q-E-A-G-I-I-S-K-E-A-P-I-H-L-S-N-L-A-I-A-D-P-K-D-G-K-P-T-R-V-G-F-R-V-E-D-G-K-K-V-R-V-A-K-R-S-G-A-L-I-D-G"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-N-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-S-V-G-D-I-I-V-V-S-I-K-E-A-I-P-R-G-R-V-K-K-G-D-V-M-K-A-V-V-V-R-T-A-K-D-I-R-R-P-D-G-S-V-I-R-F-D-N-N-A-A-V-L-I-D-N-K-K-E-P-I-G-T-R-I-F-G-P-V-P-R-E-L-R-A-K-N-H-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-V-L-Q-G-V-V-V-S-D-K-N-D-K-T-V-V-V-K-V-E-R-R-Y-S-H-P-L-L-Q-K-T-V-R-Q-S-K-K-Y-K-A-H-D-E-N-N-Q-F-K-V-G-D-F-V-S-I-Q-E-S-A-P-I-S-K-D-K-R-W-V-V-L-T-S-E-A-A-G"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-M-Q-P-K-R-T-K-F-R-K-Q-F-K-G-R-I-H-G-N-S-K-G-G-T-D-L-N-F-G-A-F-G-L-K-A-L-E-P-E-R-V-T-A-R-Q-I-E-A-A-R-R-A-I-T-R-H-M-K-R-A-G-R-V-W-I-R-I-F-P-D-L-P-V-T-S-K-P-T-E-V-R-M-G-K-G-K-G-S-V-D-Y-W-A-C-R-V-A-P-G-R-V-M-F-E-L-D-G-V-P-E-D-V-A-R-E-A-L-R-L-G-A-A-K-L-P-I-K-T-R-F-I-Q-R-I-A-E"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-G-K-A-K-A-P-R-Q-L-K-D-N-E-A-K-A-V-A-R-T-L-R-V-S-P-Q-K-L-N-L-V-A-S-M-I-R-G-K-K-V-N-A-A-L-A-D-L-T-F-S-R-K-R-I-A-G-T-V-K-K-T-L-E-S-A-I-A-N-A-E-N-N-H-D-L-D-V-D-A-L-I-V-A-E-A-Y-V-G-K-S-I-V-M-K-R-F-H-V-R-D-R-G-R-A-S-R-I-E-K-P-F-S-H-L-T-I-V-V-R-E-V-A-E-K-G-K-A-A"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-D-L-R-H-Y-D-V-I-V-S-P-V-I-T-E-K-S-T-M-V-S-E-H-N-Q-V-V-F-N-V-A-R-K-A-T-K-P-E-I-K-A-A-V-E-A-L-F-G-V-K-V-T-A-V-N-T-A-V-C-K-G-K-V-K-R-F-R-G-L-V-G-R-Q-S-D-V-K-K-A-I-V-T-L-A-E-G-Q-S-I-D-V-S-T-G-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-K-A-E-K-R-E-I-N-P-D-P-K-F-G-D-L-V-I-T-K-F-M-N-A-V-M-L-H-G-K-K-S-V-A-E-S-I-V-Y-G-A-L-D-A-I-E-A-T-A-K-S-E-P-V-A-L-F-H-Q-A-L-D-N-V-A-P-H-I-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-D-V-R-P-E-R-R-Q-A-L-A-I-R-W-L-I-N-A-A-R-G-R-N-E-T-T-M-V-D-R-L-S-G-E-L-L-D-A-A-N-N-R-G-S-A-V-K-K-R-E-D-T-H-R-M-A-E-A-N-R-A-F-S-H-Y-R-W"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-D-R-A-E-K-R-E-F-V-A-W-L-N-G-A-F-K-E-S-G-S-V-V-V-A-H-Y-T-G-L-T-V-A-Q-M-S-D-L-R-S-K-M-R-D-A-G-G-S-V-K-V-A-K-N-R-L-A-K-I-A-L-Q-G-T-E-S-E-G-I-A-D-L-F-T-G-Q-T-V-V-A-Y-A-N-D-P-I-T-A-P-K-V-A-V-E-F-A-K-A-N-D-K-L-V-I-L-G-G-A-M-G-A-T-T-L-N-A-D-G-V-K-S-L-A-S-L-P-S-L-D-E-L-R-A-K-L-V-G-M-I-Q-T-P-A-Q-R-L-A-V-L-T-S-A-P-A-G-Q-I-A-R-V-I-G-A-H-A-R-K-N-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-A-G-Q-L-K-L-Q-V-P-A-G-A-A-N-P-S-P-P-I-G-P-A-L-G-Q-R-G-I-N-I-M-E-F-C-K-A-F-N-A-A-S-Q-E-M-E-K-G-S-P-I-P-V-L-I-T-Y-Y-Q-D-K-S-F-T-F-V-M-K-T-P-P-V-T-Y-F-L-K-K-A-A-N-L-K-S-G-S-K-T-P-G-K-A-S-A-G-T-I-T-R-D-K-V-R-A-I-A-E-A-K-M-K-D-L-N-A-A-D-V-E-A-A-M-R-M-I-E-G-S-A-R-S-M-G-L-E-V-V-G"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-W-V-G-L-G-G-G-V-G-S-L-G-R-W-W-I-G-R-I-V-G-E-Y-H-H-G-A-F-P-L-G-T-F-L-I-N-I-S-G-A-F-V-I-G-Y-L-S-V-L-F-G-V-D-W-H-D-R-Y-G-T-M-L-N-A-G-V-L-T-G-I-L-G-G-Y-T-T-F-S-S-M-Q-L-D-A-V-K-L-S-H-K-G-Q-G-G-L-A-V-F-Y-L-V-A-S-V-L-S-G-L-F-A-A-W-L-G-A-M-L-A-H-L-Q-G"} +{"text": "### FUNCTION Acts as a global negative controlling element, employing Fe as a cofactor to bind the operator of the repressed genes ### SEQUENCE -M-N-K-P-Y-T-K-P-D-Y-E-Q-E-L-R-R-A-G-V-R-I-T-R-P-R-R-I-I-L-N-I-L-N-E-T-E-D-H-P-D-A-L-E-I-F-R-R-A-V-E-E-D-D-S-I-S-L-S-T-V-Y-H-T-M-K-L-L-E-E-R-G-A-I-H-R-H-A-F-A-G-G-P-S-R-F-E-Q-A-S-G-A-H-H-D-H-I-I-D-M-D-S-G-D-V-V-E-F-H-S-D-K-I-E-K-L-Q-E-E-I-A-R-S-L-G-F-E-I-V-H-H-R-L-E-L-Y-C-K-K-L-K-S"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-I-N-G-N-E-I-R-P-G-N-V-I-E-H-E-G-G-L-W-V-A-V-K-T-N-A-V-K-P-G-K-G-G-A-Y-N-Q-V-E-L-K-N-L-I-N-G-T-K-L-N-E-R-F-R-A-A-E-S-V-E-R-V-R-L-E-Q-K-D-F-S-F-L-Y-E-Q-G-E-A-L-I-F-M-D-T-E-T-Y-E-Q-L-E-L-Q-K-D-F-V-G-D-R-A-A-F-L-Q-D-G-M-M-V-T-V-E-L-Y-E-E-K-P-I-G-I-R-L-P-D-Q-V-T-L-A-I-T-E-A-D-P-V-V-K-G-Q-T-A-A-S-S-Y-K-P-A-V-L-E-N-G-I-R-I-P-V-P-P-F-I-A-S-G-E-R-V-I-V-D-T-N-E-L-T-Y-I-S-R-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-T-S-S-L-I-S-G-V-A-Q-R-C-A-G-S-L-F-E-L-A-L-D-A-N-S-V-A-S-V-E-K-D-L-G-R-F-E-A-L-L-S-G-S-E-D-L-R-R-L-I-S-S-P-V-F-S-S-E-D-Q-L-H-A-I-G-A-I-A-D-K-A-G-I-K-G-L-V-G-N-F-L-R-V-V-A-Q-N-R-R-L-F-A-L-P-G-I-I-A-A-F-R-Q-I-A-A-E-H-R-G-E-I-S-A-D-V-V-S-A-H-E-L-T-S-A-Q-Q-N-E-L-K-A-T-L-K-G-V-A-G-K-D-V-T-I-N-V-T-V-D-P-S-I-L-G-G-L-I-V-K-M-G-S-R-Q-I-D-T-S-L-R-T-K-L-S-S-L-K-L-A-L-K-E-V-G"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-S-E-H-K-G-P-T-G-A-M-V-D-P-E-S-L-P-Y-R-P-C-V-G-L-M-V-L-N-K-A-G-L-V-W-A-G-R-R-I-V-I-P-G-D-E-M-D-G-A-T-Q-L-W-Q-M-P-Q-G-G-I-D-K-G-E-D-P-A-Q-A-A-L-R-E-L-Y-E-E-T-G-M-T-S-V-S-L-L-E-E-A-S-D-W-I-N-Y-D-L-P-P-H-L-V-G-L-A-L-K-G-K-Y-R-G-Q-T-Q-K-W-F-A-Y-R-F-E-G-D-E-S-E-I-A-I-N-P-P-P-G-G-H-T-A-E-F-D-C-W-E-W-K-P-M-A-D-L-P-N-L-I-V-P-F-K-R-K-V-Y-E-Q-V-V-A-T-F-R-H-L-A-A"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-T-V-G-L-F-G-G-S-F-N-P-P-H-G-G-H-A-L-V-A-E-I-A-I-R-R-L-K-L-D-Q-L-W-W-M-V-T-P-G-N-P-L-K-D-S-R-E-L-A-P-L-S-E-R-L-R-L-S-E-E-V-A-E-D-P-R-I-K-V-T-A-L-E-A-A-F-H-V-R-Y-T-A-D-T-L-A-L-I-R-N-A-N-P-D-V-Y-F-V-W-V-M-G-A-D-N-L-A-S-F-H-R-W-Q-R-W-R-E-I-A-Q-N-F-P-I-A-I-I-D-R-P-G-S-T-L-S-Y-L-S-S-R-M-A-Q-T-F-S-D-S-R-L-D-E-R-Y-A-P-V-L-A-R-R-M-P-P-A-W-T-F-I-H-G-P-R-S-S-L-S-S-T-A-L-R-K-V-Q-L-K-K-A-P-S-K-K"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-P-P-L-L-K-L-A-L-E-L-G-P-L-L-V-F-F-F-A-N-A-R-G-E-M-L-I-E-R-F-P-I-L-G-S-I-G-A-P-I-F-L-A-T-A-L-F-M-A-A-T-V-I-A-L-A-I-S-W-S-M-T-R-T-L-A-I-M-P-L-V-S-G-I-V-V-L-V-F-G-A-L-T-L-W-L-H-N-D-T-F-I-K-M-K-P-T-I-V-N-T-L-F-G-G-I-L-L-G-G-L-F-F-G-K-S-L-L-G-Y-V-F-D-S-A-F-R-L-D-A-E-G-W-R-K-L-T-L-R-W-G-L-F-F-I-F-L-A-I-V-N-E-I-V-W-R-N-F-S-T-D-T-W-V-S-F-K-V-W-G-I-M-P-I-T-I-V-F-T-L-L-Q-M-P-L-I-Q-K-H-S-L-T-D-E-E-N-T-A-S"} +{"text": "### FUNCTION Catalyzes the site-selective attachment of phycocyanobilin Does not have chromophore lyase activity for ApcA1, ApcA2, ApcB, ApcD, ApcF or PecA ### SEQUENCE -M-T-H-S-T-D-I-A-T-L-A-R-W-M-A-A-D-F-S-N-Q-A-Q-A-F-E-N-P-P-F-Y-A-H-I-R-V-C-M-R-P-L-P-W-E-V-L-S-G-V-G-F-F-V-E-Q-A-Y-D-Y-M-L-N-D-P-Y-R-L-R-V-L-K-L-M-I-V-G-D-R-I-H-I-E-N-Y-T-V-K-Q-E-E-N-F-Y-G-A-S-R-D-L-N-R-L-Q-T-L-T-S-E-S-L-E-K-L-P-G-C-N-M-I-V-E-W-T-G-N-S-F-K-G-T-V-E-P-G-K-G-C-I-V-V-R-K-G-Q-K-T-Y-L-D-S-E-F-E-I-N-E-E-K-F-I-S-L-D-R-G-R-D-L-E-T-D-A-H-I-W-G-S-V-A-G-P-F-Y-F-V-R-L-H-N-F-A-D-E-V-K-I-S-A-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-A-A-T-D-Q-I-L-D-Q-L-K-S-L-S-L-L-E-A-A-E-L-V-K-Q-I-E-E-A-F-G-V-S-A-A-A-P-A-G-G-M-M-M-M-A-A-P-G-A-A-A-A-A-E-P-V-E-E-Q-T-E-F-D-V-V-L-E-S-V-P-A-D-K-K-I-A-V-L-K-I-V-R-E-I-T-G-L-G-L-K-E-A-K-D-L-V-E-A-A-P-K-A-V-K-E-A-I-A-K-D-A-A-E-D-A-K-K-R-I-E-E-A-G-G-K-V-T-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-G-R-T-L-E-N-K-K-E-I-V-A-D-L-K-E-T-L-G-E-S-T-L-A-L-V-I-E-Y-Q-G-L-T-V-A-E-I-T-D-L-R-K-R-L-R-P-S-G-T-V-C-K-V-T-K-N-T-L-M-G-I-A-I-Q-D-D-E-K-W-Q-P-L-S-E-L-L-K-G-S-S-A-F-L-L-V-K-E-D-F-S-S-A-I-K-A-Y-Q-E-F-Q-K-V-T-K-K-T-E-L-R-G-G-V-M-E-G-R-L-L-K-E-P-D-V-K-A-L-G-D-L-P-S-K-E-Q-L-M-G-Q-I-A-G-A-I-N-A-L-A-T-K-I-A-V-G-I-N-E-V-P-G-G-L-A-R-A-L-Q-A-V-A-D-K-E-N-G-G-D-D-S-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-V-A-V-I-K-L-A-L-N-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-M-F-C-K-E-Y-N-A-K-T-A-D-Q-A-G-M-V-I-P-V-E-I-S-V-Y-E-D-R-S-F-T-F-V-L-K-T-P-P-A-S-V-L-I-R-K-A-A-K-I-E-R-G-S-N-E-P-N-K-K-K-V-G-T-I-T-T-A-Q-L-R-E-I-A-Q-T-K-L-P-D-L-N-A-N-D-I-D-A-A-M-K-I-V-A-G-T-A-R-N-M-G-V-T-V-T-D"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-A-Q-E-I-I-R-S-I-E-A-E-Q-L-K-S-N-L-P-E-I-Y-I-G-D-T-V-R-V-G-V-K-I-K-E-G-E-K-Y-R-V-Q-P-Y-E-G-V-V-I-A-R-R-N-G-G-I-N-E-T-I-T-V-R-R-V-F-Q-G-V-G-V-E-R-V-F-L-L-H-S-P-R-I-D-N-I-K-V-L-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-G-R-V-G-K-A-T-R-I-K-Q-R-F-D-R-S-L"} +{"text": "### FUNCTION Covalently attaches a chromophore to Cys residue In vitro does not act as a chromophore lyase for ApcA1, ApcA2, ApcB, ApcD, ApcF, CpcB or PecB, the lyase activity is therefore unsure ### SEQUENCE -M-K-S-L-S-K-L-V-R-T-V-D-E-S-Q-I-I-E-F-F-Q-E-S-V-G-E-W-C-S-Q-R-R-Y-Y-T-L-P-D-G-E-T-K-E-M-M-S-M-I-T-I-R-F-L-E-Q-G-C-D-E-L-Q-K-L-A-Q-I-H-K-L-A-E-S-V-F-L-I-C-G-A-E-V-T-W-C-S-T-D-V-L-K-N-R-S-E-S-E-G-S-T-L-F-G-A-L-G-N-I-L-Y-R-D-R-G-F-A-T-S-K-P-V-T-A-Q-Y-N-F-P-N-P-K-T-L-C-L-R-T-E-Y-N-G-S-V-F-E-E-E-L-K-L-I-G-S-K-Y-R-T-R-Q-T-I-I-S-R-A-G-E-Q-L-M-I-G-Q-Y-I-E-K-R-I-V-Q"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-F-D-A-L-A-N-I-N-W-E-V-I-F-Q-L-T-S-V-A-L-I-I-I-A-G-P-A-V-I-F-V-L-A-F-R-N-G-N-L"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-D-K-S-E-S-Y-K-V-I-T-D-N-R-Q-A-R-Y-L-Y-E-I-L-E-T-F-E-A-G-I-Q-L-T-G-T-E-V-K-S-I-R-A-G-K-V-N-L-Q-D-G-Y-A-L-L-R-D-G-E-I-W-L-I-N-A-H-I-S-P-Y-N-A-S-G-Q-Y-F-N-H-E-P-R-R-T-R-K-L-L-L-H-R-Q-E-I-R-K-L-I-G-K-V-E-Q-Q-G-L-T-L-V-P-L-K-M-Y-L-K-R-G-W-V-K-V-S-I-A-L-G-K-G-K-K-L-H-D-K-R-E-S-L-K-R-R-Q-D-Q-R-D-M-Q-R-A-M-K-N-Y"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-T-G-K-G-Q-G-F-G-F-G-L-G-K-M-K-E-L-A-E-A-F-K-K-A-Q-Q-V-Q-E-G-A-K-R-L-Q-E-E-L-E-Q-M-E-I-Q-G-E-A-G-G-G-L-V-K-V-I-V-S-G-N-Q-E-P-K-R-V-E-I-S-P-D-A-L-A-Q-G-A-D-L-L-S-D-L-V-T-A-A-M-K-D-A-Y-I-K-S-T-A-T-M-R-E-R-M-E-D-L-T-S-G-L-E-L-P-G-F"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Y-A-R-P-L-A-R-L-I-E-Q-L-Q-R-L-P-G-V-G-P-K-T-A-Q-R-L-A-L-H-I-L-K-R-P-E-S-E-V-E-A-L-A-Q-A-L-V-E-A-K-K-Q-I-G-L-C-S-V-C-F-H-L-S-S-E-P-V-C-E-I-C-R-N-P-N-R-E-N-N-T-I-C-V-V-A-D-S-R-D-V-I-A-L-E-K-T-R-E-F-K-G-K-Y-H-V-L-G-G-V-I-S-P-M-D-G-I-G-P-E-Q-L-T-I-T-P-L-L-R-R-V-S-Q-Q-Q-P-K-E-V-I-L-A-I-S-P-S-V-E-G-E-T-T-T-L-Y-V-G-Q-L-L-K-P-F-T-K-V-T-R-I-A-F-G-L-P-V-G-G-D-L-E-Y-A-D-E-I-T-L-A-R-A-L-E-G-R-R-E-L-D"} +{"text": "### FUNCTION Might act as a photo-protectant, protecting against damage induced by excess light via a process known as non-photochemical quenching ### SEQUENCE -M-T-F-T-S-D-S-A-S-T-R-F-S-Q-A-F-G-I-Q-T-G-D-A-V-A-S-T-I-T-V-F-Q-A-L-S-I-D-D-Q-L-A-V-L-W-Y-A-Y-T-E-M-G-R-S-I-T-P-A-A-T-G-A-A-R-L-Q-L-A-E-G-L-L-N-Q-I-K-Q-M-S-H-A-E-Q-L-Q-V-M-R-D-L-A-A-K-N-N-T-Q-V-S-R-S-Y-G-I-L-S-N-N-T-K-L-A-F-W-Y-E-L-S-E-L-M-V-K-G-F-V-V-P-V-P-T-D-Y-K-I-S-R-D-G-S-Q-V-L-E-A-L-K-G-L-D-F-G-Q-Q-I-T-V-L-R-K-V-V-A-D-M-G-V-D-P-L-A-D"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-T-V-Y-E-T-L-Y-I-L-R-P-D-L-T-D-E-Q-V-E-L-A-I-A-K-Y-Q-N-L-L-Q-E-Q-G-A-T-D-L-E-V-Q-N-R-G-K-R-R-L-A-Y-E-I-K-K-Q-R-D-G-F-Y-V-Q-F-N-Y-N-A-P-G-K-A-I-A-I-L-E-R-A-M-R-L-S-E-E-V-I-R-Y-L-T-V-K-Q-E-V-T-K-E-K-E-D-K-V-A-V-T-A"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-A-L-T-V-E-T-K-K-R-P-E-G-S-K-P-K-A-L-R-R-A-G-F-I-P-A-N-L-Y-G-H-N-G-R-E-S-I-S-L-V-V-D-A-K-V-V-E-R-L-L-K-A-A-A-V-K-K-T-E-I-E-L-N-I-P-E-L-E-W-T-G-K-T-I-L-Q-E-V-Q-I-H-P-A-K-G-T-P-Y-H-I-S-F-L-A-T-A-K-G"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-L-K-R-S-K-F-E-T-T-Q-S-Q-I-M-H-R-A-E-D-L-I-S-A-A-S-N-R-Y-R-I-T-V-Q-V-A-N-R-A-K-R-R-R-Y-E-E-F-E-S-A-E-D-A-M-M-K-P-V-L-R-A-I-I-E-M-S-D-E-L-T-Q-P-E-I-I-G-E-I"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-P-V-I-E-K-K-R-T-R-D-L-P-Q-I-N-E-R-I-R-F-P-K-I-R-V-I-D-T-D-G-S-Q-L-G-I-L-T-P-Q-E-A-L-Q-L-A-E-E-K-E-L-D-L-V-L-L-S-D-K-A-D-P-P-V-C-R-I-M-D-Y-G-K-Y-K-F-E-Q-E-K-K-A-R-E-A-R-K-K-Q-H-T-A-D-V-K-E-V-K-M-R-Y-K-I-E-E-H-D-Y-N-V-R-V-K-Q-A-E-R-F-L-K-D-G-D-K-V-K-A-T-V-M-F-R-G-R-E-I-Q-H-S-D-L-A-E-D-L-L-K-R-M-A-T-D-L-E-P-F-G-E-V-Q-Q-A-P-K-K-E-G-R-N-M-M-M-L-I-S-P-K-K"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-S-F-E-Y-P-Q-D-L-R-Y-L-D-T-H-E-Y-V-R-L-D-G-E-I-A-T-I-G-I-T-E-F-A-V-D-Q-L-G-D-V-V-F-L-E-L-P-D-I-G-D-L-L-T-K-G-D-T-F-G-S-I-E-S-V-K-A-V-E-N-L-N-A-P-I-T-G-T-V-V-E-R-N-E-I-L-V-E-S-P-E-A-V-A-D-D-P-Y-G-E-G-W-F-L-K-V-R-V-N-D-P-D-E-V-N-D-A-L-T-A-D-E-Y-R-A-E-V-E-G-E"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-K-S-L-I-R-D-I-P-D-F-P-K-P-G-I-L-F-R-D-I-T-T-L-L-R-D-R-Q-G-L-R-Y-T-I-D-F-L-A-E-K-C-S-E-A-N-L-N-I-D-Y-V-I-G-M-E-S-R-G-F-I-F-G-T-P-L-A-Y-K-L-G-A-G-F-I-P-V-R-K-K-G-K-L-P-A-A-V-H-S-I-E-Y-E-L-E-Y-G-T-D-C-L-E-V-H-R-D-A-L-H-P-D-S-R-V-L-I-V-D-D-L-I-A-T-G-G-T-A-S-A-T-A-K-L-V-Q-Q-I-G-C-E-L-V-G-F-G-F-I-I-E-L-R-D-L-Q-G-R-K-H-L-P-D-V-P-I-I-S-L-V-E-Y"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-Y-Y-R-R-R-L-S-P-I-K-P-G-E-P-I-D-Y-K-D-V-D-L-L-R-K-F-I-T-E-R-G-K-I-L-P-R-R-I-T-G-L-T-A-K-Q-Q-R-E-L-T-L-A-I-K-R-S-R-L-V-A-L-L-P-F-I-N-A-E-G"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-P-I-G-V-P-K-V-P-Y-R-M-P-G-G-Q-F-T-D-W-I-S-I-Y-D-R-L-Y-R-E-R-I-I-F-L-G-R-D-V-D-D-E-I-A-N-Q-I-I-A-V-M-L-Y-L-D-S-E-D-P-G-K-D-I-Y-L-Y-I-N-S-P-G-G-M-V-T-S-G-L-A-I-Y-D-T-M-Q-H-I-K-S-D-V-V-T-I-C-V-G-L-A-A-S-M-G-S-F-L-L-A-A-G-T-K-G-K-R-M-A-L-P-H-S-R-I-M-I-H-Q-P-S-G-G-T-R-G-Q-A-T-D-I-E-I-E-A-R-E-I-L-R-I-R-H-Q-L-N-Q-I-Y-A-N-N-T-S-Q-P-L-A-K-I-E-K-D-M-D-R-D-F-F-M-S-A-Q-E-A-M-E-Y-G-L-I-D-R-V-I-E-E-R-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-G-V-I-Q-R-R-P-V-P-P-D-S-V-Y-N-S-R-L-V-S-M-I-I-R-R-I-M-R-H-G-K-K-S-L-A-A-R-I-V-Y-D-A-L-K-T-I-E-E-R-T-G-N-N-A-L-E-V-F-E-R-A-V-R-N-A-T-P-L-V-E-V-K-A-R-R-V-G-G-A-T-Y-Q-V-P-M-E-V-R-T-E-R-G-T-T-L-A-L-R-W-L-V-Q-F-S-R-S-R-P-G-R-T-M-A-S-R-L-A-N-E-L-L-D-A-A-N-E-S-G-N-A-I-R-K-R-E-E-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-Y"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-T-L-Q-Q-Q-K-I-R-I-R-L-Q-A-F-D-R-R-L-L-D-T-S-C-E-K-I-V-D-T-A-N-R-T-N-A-T-A-I-G-P-I-P-L-P-T-K-R-K-I-Y-C-V-L-R-S-P-H-V-D-K-D-S-R-E-H-F-E-T-R-T-H-R-R-I-I-D-I-Y-Q-P-S-S-K-T-I-D-A-L-M-K-L-D-L-P-S-G-V-D-I-E-V-K-L"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-T-A-S-T-T-I-N-K-G-D-S-P-N-G-D-S-S-A-S-S-V-L-H-Q-K-V-L-G-S-R-R-F-S-N-Y-W-W-A-S-I-V-T-L-G-A-S-G-F-F-L-A-G-I-S-S-Y-L-R-V-N-L-L-I-V-T-D-P-T-Q-L-I-F-V-P-Q-G-L-V-M-G-L-Y-G-T-A-G-L-L-L-A-S-Y-L-W-L-V-I-L-W-D-L-G-G-G-Y-N-D-F-N-R-E-T-G-N-I-K-I-F-R-W-G-F-P-G-K-N-R-K-I-E-I-G-S-R-I-Q-D-I-Q-S-V-R-V-D-I-K-E-G-L-N-P-R-R-A-L-Y-L-R-V-K-G-R-R-D-I-P-L-T-R-V-G-Q-P-L-S-L-A-E-L-E-T-Q-G-A-Q-L-A-R-F-L-G-V-P-L-E-G-L"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-S-F-I-R-E-I-L-R-A-I-R-I-T-L-I-F-W-L-V-T-A-I-I-Y-P-L-A-I-L-V-V-G-Q-G-L-F-P-I-Q-A-N-G-S-I-M-E-N-I-E-G-T-P-I-G-S-T-L-I-S-Q-V-F-T-S-E-K-Y-F-H-S-R-P-S-A-V-R-Y-S-Q-G-R-K-A-K-P-T-G-I-S-G-G-S-N-L-A-P-S-N-P-A-L-L-E-R-I-I-E-E-A-N-Q-L-R-D-E-N-V-Q-P-I-A-D-L-I-Y-S-S-G-S-G-L-D-P-H-I-S-V-Q-A-A-R-Q-Q-L-E-R-V-A-R-A-R-G-V-Q-P-D-E-I-L-L-A-I-N-K-F-T-D-G-R-F-L-G-I-F-G-E-P-G-V-N-V-L-R-L-N-Y-A-L-D-L-Q-D-I-N-R-Q-Q-N"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-A-L-I-T-T-G-N-G-L-I-R-D-L-E-K-F-G-S-V-G-V-Y-V-P-L-E-G-G-F-E-G-R-Y-R-R-R-L-R-A-A-G-Y-T-T-L-Q-F-T-A-R-G-L-G-D-V-A-A-Y-L-T-G-V-H-G-V-R-P-P-H-L-G-K-K-S-S-G-N-G-A-A-V-G-N-V-Y-Y-L-P-P-I-V-G-S-Q-L-E-H-L-P-P-K-S-K-G-L-V-L-W-I-I-E-G-H-I-L-S-D-Q-E-V-E-F-L-T-S-L-P-S-L-E-P-R-V-K-V-V-V-E-R-G-G-D-R-T-F-R-W-K-A-L-K-D-T-F-S-A-S-Y-Q-A-V"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-A-K-F-D-P-R-N-L-P-D-L-V-R-R-P-I-L-T-E-K-A-T-I-M-M-E-Q-N-K-Y-T-F-E-V-T-P-K-A-S-K-P-Q-I-R-A-A-I-E-D-L-F-Q-V-K-V-V-K-V-N-T-A-L-P-P-R-R-K-K-R-V-G-K-F-I-G-F-K-P-Q-Y-K-K-A-I-V-T-I-A-P-G-D-V-D-K-I-R-Q-V-L-F-P-E-V"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-I-A-D-H-L-L-S-K-I-E-K-L-N-D-R-N-E-K-Q-V-I-K-T-W-S-R-A-S-T-I-L-P-L-M-V-G-H-T-I-A-V-H-N-G-R-Q-H-V-P-V-F-I-S-E-Q-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-G-K-S-D-K-K-A-G-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-T-D-T-T-E-V-K-A-I-A-R-F-I-R-M-S-P-Y-K-V-R-R-V-L-D-Q-I-R-G-L-S-Y-R-E-A-L-I-I-L-E-F-M-P-Y-R-A-T-E-P-V-L-T-L-L-R-S-A-A-A-N-A-E-H-N-A-G-L-D-R-A-E-L-V-I-T-Q-A-Y-A-D-Q-G-P-V-L-K-R-F-Q-P-R-A-Q-G-R-A-Y-Q-I-R-K-P-T-C-H-I-T-L-A-V-A-A-N-A-G-A-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-S-P-R-R-T-K-F-R-K-Q-Q-R-G-R-M-G-G-L-A-H-R-G-S-T-L-N-F-G-D-F-A-L-Q-A-Q-E-P-A-W-I-T-S-R-Q-I-E-A-S-R-R-A-M-T-R-Y-I-R-R-G-G-K-I-W-I-R-I-F-P-D-K-P-V-T-M-R-P-A-E-T-R-M-G-S-G-K-G-N-P-E-F-W-V-A-V-V-K-P-G-R-I-L-F-E-I-A-G-V-T-E-E-I-A-R-E-A-M-R-L-A-A-Y-K-L-P-I-K-T-K-F-I-V-R-S-Q-V-V-E-E-Q-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-I-K-E-R-V-G-L-V-V-S-D-K-M-Q-K-T-V-V-V-A-I-E-N-R-A-P-H-P-K-Y-G-K-I-V-V-K-T-R-R-Y-K-A-H-D-E-D-N-K-C-K-V-G-D-R-V-R-I-Q-E-T-R-P-L-S-K-T-K-R-W-Q-V-A-E-I-L-N-T-K-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-P-Q-T-Y-L-N-V-A-D-N-S-G-A-R-K-L-M-C-I-R-V-L-G-A-G-N-S-R-Y-G-F-I-G-D-K-I-I-A-V-V-K-D-A-T-P-N-M-A-V-K-K-S-D-V-V-E-A-V-I-V-R-T-R-H-H-I-R-R-D-S-G-M-T-I-R-F-D-D-N-A-A-V-I-I-N-K-D-G-N-P-R-G-T-R-V-F-G-P-V-A-R-E-L-R-D-K-N-F-T-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-K-D-T-T-P-K-F-H-K-L-H-V-K-T-G-D-T-V-Q-I-I-A-G-K-D-K-G-K-V-G-E-V-I-K-A-L-P-Q-L-S-K-V-V-V-K-G-V-N-I-K-T-K-Q-I-I-A-G-K-D-K-G-K-V-G-E-V-I-K-A-L-P-Q-L-S-K-V-V-V-K-G-V-N-I-K-T-K-H-V-K-P-Q-Q-E-G-E-S-G-R-I-V-T-Q-E-A-P-I-H-S-S-N-V-M-L-Y-S-T-K-Q-N-V-A-S-R-V-C-Y-T-F-T-A-E-G-K-K-V-R-K-L-K-K-T-G-E-I-L-D-N"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-T-T-R-L-K-T-L-Y-Q-E-T-I-V-P-K-L-T-Q-Q-F-Q-Y-T-N-V-H-Q-V-P-K-L-V-K-I-T-V-N-R-G-L-G-E-A-A-Q-N-A-K-S-L-E-A-S-L-T-E-I-A-T-I-T-G-Q-K-P-V-V-T-R-A-K-K-A-I-A-G-F-K-I-R-Q-G-M-P-V-G-I-M-V-T-L-R-G-E-R-M-Y-A-F-F-D-R-L-I-S-L-S-L-P-R-I-R-D-F-R-G-I-S-P-K-S-F-D-G-R-G-N-Y-T-L-G-V-R-E-Q-L-I-F-P-E-I-E-Y-D-S-I-D-Q-I-R-G-L-D-I-S-I-I-T-T-A-K-N-D-E-E-G-R-A-L-L-K-E-F-G-M-P-F-R-D-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-A-A-N-D-T-I-A-D-M-L-T-R-I-R-N-A-N-M-A-R-H-Q-T-T-L-V-P-A-T-K-M-T-R-S-I-A-K-V-L-Q-E-E-G-F-I-A-E-I-S-E-E-G-D-E-V-K-R-N-L-V-I-A-L-K-Y-K-G-K-N-R-Q-P-L-I-T-A-L-K-R-V-S-K-P-G-L-R-V-Y-S-N-R-K-E-L-P-R-V-L-G-G-I-G-I-A-I-I-S-T-S-S-G-I-M-T-D-R-E-A-R-R-Q-N-V-G-G-E-V-L-C-Y-V-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-R-P-I-T-V-P-A-K-V-Q-V-T-I-D-G-T-K-V-V-V-K-G-P-K-G-E-L-S-R-E-L-P-A-N-V-S-V-S-Q-E-G-E-T-L-Q-V-T-R-R-D-E-T-R-T-S-R-Q-L-H-G-L-S-R-T-L-V-A-N-M-V-E-G-V-S-Q-G-F-Q-R-R-L-E-I-Q-G-V-G-Y-R-A-Q-V-Q-G-R-N-L-V-L-N-M-G-Y-S-H-Q-V-Q-I-E-P-P-D-G-I-Q-F-V-V-E-N-N-T-N-V-I-V-S-G-Y-D-K-E-I-V-G-N-T-A-A-K-V-R-A-V-R-P-P-E-P-Y-K-G-K-G-I-R-Y-A-G-E-V-V-R-R-K-A-G-K-T-G-K-G-G-K-K"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-T-G-R-R-K-A-N-R-T-K-K-E-E-T-N-W-Q-E-R-V-I-Q-I-R-R-V-S-K-V-V-K-G-G-K-K-L-S-F-R-A-I-V-V-V-G-N-E-R-G-Q-V-G-V-G-V-G-K-A-S-D-V-I-G-A-V-K-K-G-V-A-D-G-K-K-H-L-I-D-I-P-I-T-K-S-N-S-I-P-H-P-I-D-G-V-G-G-G-A-K-V-M-M-R-P-A-A-P-G-T-G-V-I-A-G-G-A-V-R-T-V-L-E-L-A-G-V-R-N-V-L-A-K-Q-L-G-S-N-N-P-L-N-N-A-R-A-A-V-N-A-L-S-T-L-R-T-L-A-E-V-A-E-D-R-G-I-A-I-E-K-L-Y-I"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-D-V-K-P-Q-K-G-S-K-K-R-R-R-R-V-G-R-G-I-S-A-G-Q-G-A-S-A-G-L-G-M-R-G-Q-K-S-R-S-G-S-G-T-R-P-G-F-E-G-G-Q-Q-P-L-Y-R-R-I-P-K-L-K-G-F-P-V-V-N-R-K-I-Y-T-T-I-N-V-E-K-L-A-D-L-P-A-N-T-E-V-T-L-E-S-L-R-A-A-G-I-L-T-A-A-K-G-P-L-K-I-L-G-N-G-D-L-G-V-A-L-N-V-K-A-A-A-F-T-G-Q-A-R-S-K-I-E-A-A-G-G-S-C-E-V-L-G"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-Q-D-L-I-E-M-E-G-T-V-T-E-S-L-P-N-A-M-F-R-V-D-L-D-N-G-F-N-V-L-A-H-I-S-G-K-I-R-R-N-Y-I-K-I-L-P-G-D-R-V-K-V-E-L-T-P-Y-D-L-T-K-G-R-I-T-Y-R-L-R-K-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-L-P-R-D-K-R-V-E-I-G-L-T-Y-I-Y-G-I-G-L-S-R-S-Q-E-I-I-A-A-T-G-V-N-P-D-T-R-V-K-D-L-S-D-A-D-V-A-A-L-R-G-E-V-E-S-N-Y-Q-V-E-G-D-L-R-R-L-E-A-M-N-I-K-R-L-V-D-I-G-T-Y-R-G-R-R-H-R-M-G-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-R-G-R-R-Q-T-V-A-G-K-K-K-A-P-G-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-R-Q-P-T-K-K-S-G-S-K-K-Q-K-R-N-V-P-N-G-M-A-Y-I-Q-S-T-F-N-N-S-I-V-T-I-T-D-Q-N-G-D-V-I-S-W-A-S-A-G-S-S-G-F-K-G-A-K-K-G-T-P-F-A-A-Q-T-A-A-E-S-A-A-R-R-A-I-D-Q-G-M-R-Q-I-E-V-M-V-S-G-P-G-A-G-R-E-T-A-I-R-A-L-Q-G-A-G-L-E-I-T-L-I-R-D-I-T-P-I-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-S-K-T-Y-L-P-P-Q-E-S-L-E-R-D-W-Y-V-V-D-A-T-D-K-R-L-G-R-L-A-S-E-I-A-M-I-L-R-G-K-N-K-A-H-Y-T-P-H-L-D-T-G-D-F-V-I-V-V-N-A-K-K-V-A-V-T-G-K-K-R-T-Q-K-L-Y-R-R-H-S-G-R-P-G-G-M-K-T-E-T-F-A-K-L-Q-Q-R-L-P-E-R-I-V-E-H-A-V-K-G-M-L-P-K-N-S-L-G-K-Q-L-F-T-K-L-K-V-Y-A-G-P-T-H-P-H-D-A-Q-K-P-K-E-L-N-I-H-T-I-P-G-A-E-S"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-A-K-S-D-I-H-P-K-W-Y-P-E-A-K-V-Y-C-N-G-Q-V-V-M-T-V-G-S-T-K-P-E-L-H-V-D-V-W-S-G-N-H-P-F-Y-T-G-T-Q-K-I-I-D-T-E-G-R-V-E-R-F-L-R-K-Y-G-M-S-S-T-Q-T-S-G-E-Q-T-K-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-A-V-F-E-G-T-F-T-Q-T-E-P-L-R-L-A-V-V-I-G-R-F-N-D-L-V-T-T-K-L-L-A-G-C-Q-D-C-L-K-R-H-G-V-D-P-D-P-H-G-N-Q-V-D-Y-V-W-V-P-G-S-F-E-V-P-L-V-A-R-Q-L-A-L-T-H-R-Y-D-A-I-I-C-L-G-A-V-I-R-G-Q-T-P-H-F-D-Y-V-S-A-E-V-S-K-G-I-A-A-A-S-F-Q-T-G-V-P-V-I-F-G-I-L-T-V-D-T-M-Q-Q-A-L-E-R-A-G-I-K-A-N-H-G-W-D-Y-A-M-N-A-L-E-M-A-S-L-M-R-Q-L-R-S-N-V-T-D-S-Y-S-Q-T-Q-S-L-P-A-A-F-P-N-A-S-I-G-K-L-T-A-E-S-E-E-V"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -M-T-I-I-F-Q-F-A-L-V-A-L-V-L-V-S-F-V-L-V-V-G-V-P-V-A-Y-A-T-P-Q-N-W-V-E-S-K-K-L-L-W-L-G-S-G-V-W-I-A-L-V-L-L-V-G-L-L-N-F-F-V-V"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-E-R-E-K-K-R-A-K-L-V-E-K-Y-S-E-K-R-E-A-L-L-E-E-F-R-T-T-E-S-P-L-E-K-L-E-I-H-R-Q-I-Q-Q-L-P-R-N-S-A-P-N-R-R-R-N-R-C-W-V-T-G-R-P-R-G-V-Y-R-D-F-G-L-S-R-N-V-L-R-E-W-A-H-E-G-L-L-P-G-V-V-K-S-S-W"} +{"text": "### FUNCTION Part of the energy-coupling factor transporter complex CbiMNOQ involved in cobalt import ### SEQUENCE -M-N-Q-S-K-Q-S-L-S-N-W-L-L-I-G-G-V-I-A-L-A-V-L-P-L-I-F-V-R-D-A-E-F-T-G-A-D-S-Q-A-E-K-A-I-S-E-V-K-P-G-Y-E-P-W-F-K-P-L-F-E-P-P-S-G-E-V-E-S-L-L-F-S-S-Q-A-A-L-G-A-G-I-I-G-Y-A-V-G-L-Y-K-G-R-S-Q-Q-Q-R-H-K-E"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-A-G-S-G-R-I-P-L-W-V-V-A-T-I-A-G-L-G-V-I-T-V-V-G-I-F-F-Y-G-A-Y-A-G-I-G-S-S-I"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-E-R-T-P-N-P-N-N-Q-P-V-E-L-N-R-T-S-L-Y-L-G-L-L-L-V-F-V-L-G-I-L-F-S-S-Y-F-F-N"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-H-P-L-V-P-P-I-T-D-L-A-I-P-V-A-E-Q-L-G-L-E-V-V-G-I-V-F-H-T-N-Q-R-P-P-V-L-R-I-D-I-R-N-P-Q-Q-D-T-G-L-D-D-C-E-R-M-S-R-A-L-E-A-A-L-D-A-T-E-I-I-P-D-A-Y-V-L-E-V-S-S-P-G-I-S-R-Q-L-V-T-D-R-E-F-I-S-F-K-G-F-P-V-I-V-S-T-S-P-P-H-E-E-Q-Q-E-W-I-G-Q-L-I-R-R-D-E-T-K-V-Y-I-N-Q-K-G-R-V-I-E-I-P-R-P-L-I-T-R-V-L-L-Y-D-G-E"} +{"text": "### FUNCTION Involved in protection of chromosomal DNA from damage under nutrient-limited and oxidative stress conditions Binds heme ### SEQUENCE -M-A-D-T-Q-T-L-L-Q-N-F-G-Q-V-Y-D-N-P-V-L-L-D-R-S-V-T-A-P-V-T-E-G-L-N-V-L-L-A-S-F-Q-A-L-Y-L-Q-Y-Q-K-H-H-F-V-V-E-G-A-E-F-Y-S-L-H-E-F-F-N-S-S-Y-N-E-V-Q-D-H-V-H-E-I-G-E-R-L-N-G-L-G-G-V-P-A-A-S-F-S-K-L-A-E-L-T-C-F-E-Q-E-S-D-G-V-Y-S-S-R-K-M-V-E-N-D-L-A-A-E-Q-A-I-I-N-V-I-R-R-Q-A-A-Q-A-E-S-L-G-D-R-G-T-R-Y-L-Y-E-K-I-L-L-K-T-E-E-R-A-Y-H-L-A-H-F-L-A-K-D-S-L-T-L-G-F-V-Q-P-A-Q-N"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-A-V-S-L-S-V-S-T-V-K-P-L-G-D-R-V-F-V-K-V-S-A-S-E-E-K-T-A-G-G-L-Y-L-P-D-T-A-K-E-K-P-Q-V-G-E-V-V-A-L-G-A-G-K-R-N-D-D-G-S-R-Q-E-L-E-V-K-V-G-D-K-V-L-Y-S-K-Y-A-G-T-D-V-K-L-G-T-E-E-Y-V-L-L-S-E-K-D-I-L-A-V-V-G"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-I-L-E-L-L-D-K-L-F-L-R-T-P-D-T-S-R-S-H-V-K-R-R-L-Q-L-V-I-A-H-D-R-A-G-L-D-P-E-T-L-E-K-M-R-K-E-I-L-D-I-V-C-R-Y-V-E-V-E-P-D-G-L-E-F-A-L-E-S-N-Q-R-T-T-A-L-I-A-N-L-P-I-R-R-V-K-P-E-L-P-I-F-D-E-T-S-Q"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-V-K-R-G-N-V-A-R-K-R-R-N-K-I-L-K-L-A-K-G-F-R-G-S-H-S-T-L-F-R-T-A-N-Q-Q-V-M-K-A-L-R-S-A-Y-R-D-R-K-K-K-K-R-D-F-R-R-L-W-I-T-R-I-N-A-A-S-R-Q-H-G-L-S-Y-S-Q-L-I-G-N-L-K-K-A-D-I-Q-L-N-R-K-M-L-A-Q-L-A-V-L-D-P-A-S-F-G-K-V-A-E-L-A-S-Q-A-K-G"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-A-L-P-K-A-N-R-L-K-S-R-H-D-F-Q-A-V-F-R-E-G-L-R-R-N-S-S-H-F-T-L-R-A-L-K-P-S-S-A-R-K-S-S-L-D-T-A-A-Q-T-Q-P-V-D-E-V-Q-N-I-P-S-T-L-I-G-V-S-I-S-T-K-V-S-K-R-A-V-V-R-N-R-I-K-R-Q-I-T-A-A-M-Q-Q-L-L-P-R-L-A-P-G-W-K-L-V-V-I-V-K-P-T-A-A-E-S-K-C-G-S-Q-Q-F-L-Q-E-L-E-Q-L-L-A-Q-T-E-V-L-H-G-H-S"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-G-F-G-F-K-I-L-V-E-Q-S-I-Q-L-L-T-V-A-P-R-L-V-P-E-V-L-Q-Q-P-T-I-R-H-P-I-A-V-S-L-G-A-I-A-G-A-L-S-R-Y-Y-L-S-L-W-F-A-Q-R-F-G-I-T-F-P-Y-G-T-L-F-I-N-I-T-G-C-L-A-M-G-F-F-Y-A-L-A-L-E-R-L-S-L-I-S-P-E-I-R-L-L-V-A-V-G-F-L-G-A-Y-T-T-F-S-T-Y-A-L-D-T-F-T-L-L-G-D-R-N-L-L-A-A-G-F-Y-W-A-G-S-S-I-L-G-V-I-S-I-Q-I-G-I-I-L-G-R-L-C-Q"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-T-Q-K-N-D-N-F-V-D-K-S-F-T-V-M-A-D-I-I-L-K-I-L-P-T-N-K-K-A-K-E-A-F-V-Y-Y-R-D-G-M-S-A-Q-A-E-G-E-Y-A-E-A-L-E-Y-Y-E-E-A-L-T-L-E-E-D-T-N-D-R-G-Y-I-L-Y-N-M-G-L-I-Y-A-S-N-G-D-H-D-K-A-L-E-L-Y-H-Q-A-I-E-L-N-P-R-L-P-Q-A-L-N-N-I-A-V-I-Y-H-Y-Q-G-E-K-A-K-E-T-G-D-H-D-G-G-E-A-L-F-D-Q-A-A-D-Y-W-I-R-A-I-R-M-A-P-N-N-Y-I-E-A-Q-N-W-L-K-T-T-G-R-M-Q-I-D-V-F-F"} +{"text": "### FUNCTION Probably a ribosomal protein or a ribosome-associated protein ### SEQUENCE -M-T-K-F-I-L-K-I-L-W-L-D-E-N-V-A-L-A-V-D-Q-V-V-G-K-G-T-S-P-L-T-K-Y-F-F-W-P-R-N-D-A-W-E-E-L-K-K-E-L-E-S-K-H-W-I-S-D-L-D-R-V-E-L-L-N-K-A-T-E-V-I-N-Y-W-Q-E-E-G-R-N-R-P-M-A-E-A-Q-L-K-F-P-E-V-T-F-T-G-S-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-T-K-Y-I-S-A-L-G-L-D-V-G-R-K-R-V-G-V-A-G-C-D-R-T-G-L-I-A-T-G-I-T-T-V-E-R-T-S-F-D-R-D-V-Q-Q-I-Q-N-I-V-N-E-R-Q-V-Q-V-L-V-V-G-L-P-Y-S-M-D-G-S-L-G-F-Q-A-R-Q-V-Q-K-F-T-S-R-L-A-K-A-L-Q-L-P-V-E-Y-V-D-E-R-L-T-S-F-Q-A-E-Q-M-L-I-A-E-N-V-S-P-S-R-N-K-G-L-I-D-R-K-A-A-A-L-I-L-Q-Q-W-L-D-I-R-R-T-N-A-Q-S-S-V-A-V-E-Y"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-P-S-E-I-A-V-E-K-K-K-L-K-N-P-P-L-Q-L-H-Y-L-G-D-R-V-L-R-Q-P-A-K-R-I-T-K-V-D-D-E-T-R-Q-L-I-R-D-M-L-Q-T-M-Y-S-S-D-G-I-G-L-A-A-P-Q-V-G-I-N-K-Q-L-I-V-I-D-C-E-P-D-N-P-A-N-P-P-L-I-L-I-N-P-T-I-K-Q-V-S-R-E-I-C-S-A-Q-E-G-C-L-S-I-P-G-V-Y-M-D-V-K-R-P-E-V-V-E-V-A-Y-K-D-E-N-G-R-P-Q-T-L-K-A-T-D-L-L-G-R-C-I-Q-H-E-M-D-H-L-N-G-V-V-F-V-D-R-V-D-N-S-L-T-L-A-Q-E-L-S-K-N-G-F-S-Y-Q-A-V-K-P-V-A"} +{"text": "### FUNCTION Key component of the KaiABC oscillator complex, which constitutes the main circadian regulator in cyanobacteria Complex composition changes during the circadian cycle to control KaiC phosphorylation KaiA stimulates KaiC autophosphorylation, while KaiB sequesters KaiA, leading to KaiC autodephosphorylation Phospho-Ser-431 KaiC accumulation triggers binding of KaiB to form the KaiB complex that results in KaiC autodephosphorylation ### SEQUENCE -M-N-K-A-R-K-T-Y-V-L-K-L-Y-V-A-G-N-T-P-N-S-V-R-A-L-K-T-L-K-N-I-L-E-Q-E-F-Q-G-I-Y-A-L-K-V-I-D-V-L-K-N-P-Q-L-A-E-E-D-K-I-L-A-T-P-T-L-S-K-I-L-P-P-P-V-R-K-I-I-G-D-L-S-D-R-E-R-V-L-I-G-L-D-L-L-Y-E-E-L-T-E-E-D-W-E-A-Q-S-N-L"} +{"text": "### FUNCTION Key component of the KaiABC oscillator complex, which constitutes the main circadian regulator in cyanobacteria Complex composition changes during the circadian cycle to control KaiC phosphorylation KaiA stimulates KaiC autophosphorylation, while KaiB sequesters KaiA, leading to KaiC autodephosphorylation KaiA binding to the KaiC CII domain during the subjective day yields KaiA, completing 1 cycle of the Kai oscillator ### SEQUENCE -M-T-Q-E-V-D-Q-Q-I-L-L-Q-Q-L-K-S-D-Y-R-Q-I-L-L-S-Y-F-T-T-D-K-A-L-K-E-K-I-D-K-F-I-N-A-V-F-C-A-N-I-P-V-P-E-I-I-E-I-H-M-E-L-I-D-E-F-S-K-Q-L-R-L-E-G-R-G-D-E-T-L-M-D-Y-R-L-T-L-I-D-I-L-A-H-L-C-E-A-Y-R-G-A-I-F-K"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA biosynthesis ### SEQUENCE -M-P-F-T-Y-H-R-T-I-N-F-Q-D-T-D-A-A-G-V-V-Y-F-A-N-I-L-S-I-C-H-E-G-Y-E-A-S-L-R-T-S-G-I-S-L-K-E-F-F-T-N-P-S-M-A-F-P-I-V-H-A-S-V-D-F-L-R-P-L-F-C-G-A-Q-V-I-I-S-L-V-P-Q-K-I-G-A-E-K-F-E-I-N-Y-E-I-Y-L-A-D-V-L-V-A-K-A-V-T-R-H-V-C-I-D-A-N-T-R-S-K-Q-E-L-S-M-E-I-I-Q-W-L-D-G-Y-R-K-D-T-E-E-V-E-R-R-K-A-R-E-V-V"} +{"text": "### FUNCTION Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms They allow the positioning of the organism at the favorable depth for growth This protein could be important for the shape determination of the gas vesicle ### SEQUENCE -M-T-T-T-P-I-H-P-T-R-P-Q-T-N-S-N-R-V-I-P-T-S-T-Q-G-S-T-L-A-D-I-L-E-R-V-L-D-K-G-I-V-I-A-G-D-I-S-I-S-I-A-S-T-E-L-I-H-I-R-I-R-L-L-I-S-S-V-D-K-A-R-E-M-G-I-N-W-W-E-N-D-P-Y-L-S-S-K-S-Q-R-L-V-E-E-N-Q-Q-L-Q-Q-R-L-E-S-L-E-T-Q-L-R-L-L-T-S-A-A-K-E-E-T-T-L-T-A-N-N-P-E-D-L-Q-P-M-Y-E-V-N-S-Q-E-G-D-N-S-Q-L-E-A"} +{"text": "### FUNCTION May play a structural or regulatory role in gas vesicle synthesis ### SEQUENCE -M-V-C-T-P-V-E-K-S-P-N-L-L-P-T-T-S-K-A-N-S-K-A-G-L-A-P-L-L-L-T-V-V-E-L-I-R-Q-L-M-E-A-Q-V-I-R-R-M-E-Q-D-C-L-S-E-S-E-L-E-Q-A-S-E-S-L-Q-K-L-E-E-Q-V-L-N-L-C-H-I-F-E-I-E-P-A-D-L-N-I-N-L-G-D-V-G-T-L-L-P-S-P-G-S-Y-Y-P-G-E-I-G-N-K-P-S-V-L-E-L-L-D-R-L-L-N-T-G-I-V-V-D-G-E-I-D-L-G-L-A-Q-L-N-L-I-H-A-K-L-R-L-V-L-T-S-R-P-L"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-A-T-P-A-K-V-I-E-I-L-S-A-E-D-L-R-R-T-L-T-R-L-A-S-Q-I-V-E-R-T-R-D-L-S-Q-L-V-L-L-G-I-Y-T-R-G-V-P-L-A-E-L-L-A-R-Q-I-E-T-L-E-G-I-N-V-G-V-G-A-L-D-I-T-F-Y-R-D-D-L-D-Q-I-G-L-R-T-P-A-K-T-S-I-T-L-D-L-T-G-K-T-V-V-L-V-D-D-V-I-F-K-G-R-T-I-R-A-A-L-N-A-V-N-E-Y-G-R-P-E-V-I-R-L-A-V-L-V-D-R-G-H-R-E-V-P-I-H-P-D-F-V-G-K-Q-L-P-T-A-K-E-E-V-V-K-V-Y-L-Q-D-W-D-G-R-D-A-V-E-L-V-G-Y"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-N-P-E-L-L-P-I-I-Q-L-G-N-P-T-L-R-Q-K-A-A-W-V-E-N-I-H-D-A-T-I-Q-Q-L-I-D-D-L-I-A-T-V-A-K-A-N-G-V-G-I-A-S-P-Q-V-A-Q-S-Y-R-L-F-I-V-A-S-R-P-N-P-R-Y-P-H-A-P-E-M-E-P-T-A-M-I-N-P-K-I-V-G-H-S-T-E-I-V-E-G-W-E-G-C-L-S-V-P-G-I-R-G-L-V-P-R-H-Q-A-I-E-V-E-Y-T-D-R-Y-G-N-L-Q-K-Q-T-L-T-D-F-V-A-R-I-F-Q-H-E-F-D-H-L-D-G-V-L-F-I-D-R-V-E-S-N-L-N-T-I-T-E-E-E-Y-Q-E-L-V-T-K-N-T-K"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex ### SEQUENCE -M-L-A-I-V-A-Y-I-G-F-L-A-L-F-T-G-I-A-A-G-L-L-F-G-L-R-S-A-K-I-L"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-V-K-R-K-N-S-D-N-S-D-T-V-A-H-G-N-Y-E-A-K-V-A-E-I-E-A-I-I-S-R-I-E-S-G-E-L-E-L-E-A-V-F-E-Q-F-A-N-A-V-E-Y-L-R-Q-C-D-T-F-L-Q-Q-R-Q-Q-Q-M-D-L-L-I-E-T-L-N-D-E-D-N-S-E-L"} +{"text": "### FUNCTION NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur centers, to quinones in the respiratory and/or the photosynthetic chain The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration ### SEQUENCE -M-E-N-A-T-L-L-K-S-T-T-R-H-I-R-I-F-A-A-E-I-D-R-D-G-E-L-V-P-S-N-Q-V-L-T-L-D-I-D-P-D-N-E-F-N-W-N-E-D-A-L-Q-K-I-Y-R-K-F-D-E-L-V-E-A-S-S-G-A-D-L-T-D-Y-N-L-R-R-I-G-S-D-L-E-H-Y-L-R-S-L-L-Q-K-G-E-I-S-Y-N-L-S-A-R-V-T-N-Y-S-L-G-L-P-Q-V-A-V-E-D-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-N-K-S-A-L-K-R-A-Q-I-A-E-R-N-R-V-R-N-K-T-Y-K-S-S-V-K-T-L-M-K-N-Y-L-S-A-V-Q-A-Y-A-A-N-P-T-P-E-S-K-Q-E-A-Q-T-R-L-A-A-A-Y-S-R-I-D-K-A-V-K-R-G-I-L-H-P-N-N-G-A-R-K-K-S-R-L-A-S-K-L-K-P-I-E-Q-T-A"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-I-A-V-Y-I-V-V-A-F-F-V-A-I-F-V-F-G-F-L-S-N-D-P-A-R-N-P-G-R-R-D-L-E"} +{"text": "### FUNCTION Stabilizes the structure of photosystem II oxygen-evolving complex , the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation ### SEQUENCE -M-K-G-L-V-R-L-L-T-V-F-S-L-L-L-G-C-W-G-W-L-G-T-T-Q-I-A-Q-A-G-S-L-Q-S-F-L-V-P-Q-I-P-V-L-A-I-E-R-Q-N-R-A-D-A-K-L-A-T-E-F-G-E-K-I-D-L-N-N-T-N-V-R-A-F-Q-Q-Y-P-G-L-Y-P-T-L-A-K-K-I-I-Q-N-A-P-Y-G-K-V-E-D-V-L-N-L-P-G-L-S-D-G-Q-K-Q-L-L-Q-S-N-F-D-K-F-T-V-T-E-L-E-P-A-F-N-E-G-D-D-R-F-N-N-G-I-Y-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-K-L-A-E-A-E-S-K-M-Q-H-T-V-E-A-T-Q-R-A-F-N-T-I-R-T-G-R-A-N-A-S-L-L-D-K-V-L-V-D-Y-Y-G-S-P-T-P-L-K-S-L-A-N-I-S-T-P-D-A-T-T-I-L-I-Q-P-Y-D-K-S-S-L-N-I-V-E-K-A-I-S-L-S-D-V-G-L-T-P-S-N-D-G-A-V-I-R-L-N-I-P-P-L-T-S-D-R-R-K-E-L-V-K-I-A-A-K-Y-A-E-E-G-R-V-A-I-R-N-I-R-R-D-A-V-D-S-I-R-K-L-E-K-N-A-E-V-S-E-D-E-A-K-D-Q-Q-D-K-L-Q-K-L-T-N-K-Y-T-A-R-I-D-E-L-L-V-E-K-E-K-D-I-S-T-V"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-L-K-I-G-S-T-E-A-P-M-E-K-A-T-F-G-A-G-C-F-W-G-V-E-A-A-F-R-K-V-K-G-V-V-S-T-S-V-G-Y-M-G-G-H-F-P-N-P-C-Y-L-D-V-L-S-R-I-T-G-H-A-E-V-V-Q-I-E-Y-D-P-Q-L-V-S-Y-E-D-L-L-A-V-F-W-D-I-H-D-P-T-T-L-N-R-Q-G-P-D-K-G-E-Q-Y-R-S-V-I-F-F-H-N-E-Q-Q-A-E-A-A-Q-Q-S-K-A-K-V-Q-V-S-G-R-F-E-L-D-I-V-T-E-I-K-H-K-S-E-Y-Y-L-A-T-E-E-H-Q-Q-Y-F-E-K-Q-A-K-R"} +{"text": "### FUNCTION Manganese-binding polypeptide with L-arginine metabolizing enzyme activity Component of the core of photosystem II ### SEQUENCE -M-D-I-D-F-R-V-A-I-V-L-A-P-I-A-V-A-A-G-W-A-A-F-N-I-G-A-A-A-I-R-Q-V-Q-N-F-L-N-R-E-A"} +{"text": "### FUNCTION Involved in the binding and/or turnover of quinones at the Q site of Photosystem II ### SEQUENCE -M-T-P-S-L-S-N-F-L-W-S-L-A-W-G-T-L-I-V-V-I-P-A-T-V-G-L-I-F-I-S-Q-K-D-K-I-Q-R-S"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-E-A-A-L-L-L-A-K-L-P-E-A-Y-Q-I-F-D-P-L-V-D-V-L-P-I-I-P-V-F-F-L-L-L-A-F-V-W-Q-A-A-V-G-F-R"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-Q-V-N-D-L-G-F-V-A-S-I-L-F-V-L-V-P-S-V-F-L-I-I-L-Y-I-Q-T-A-S-R-E-G-K-K-D-S"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-P-A-I-V-L-I-I-S-V-G-A-A-L-V-A-V-T-G-Y-G-I-Y-T-A-F-G-P-P-S-R-E-L-S-D-P-F-E-D-H-E-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-Q-R-T-R-L-G-D-I-L-R-P-L-N-S-E-Y-G-K-V-A-P-G-W-G-T-T-P-V-M-G-V-F-M-A-L-F-L-V-F-L-L-I-I-L-Q-L-Y-N-K-S-I-L-I-Q-D-V-R-V-G-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-Q-Q-R-K-Q-E-I-I-N-N-Y-Q-V-H-G-T-D-T-G-S-T-D-V-Q-I-A-M-L-T-E-R-I-N-R-L-S-E-H-L-Q-A-N-K-K-D-H-S-S-R-R-G-L-L-K-L-I-G-H-R-K-R-L-L-A-Y-L-Q-Q-E-S-R-E-K-Y-Q-A-L-I-G-R-L-G-I-R-G"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-L-T-L-T-Q-L-V-T-P-N-P-D-V-A-I-T-L-T-L-F-L-T-A-E-E-R-C-R-S-R-H-R-F-E-T-E-D-G-Q-V-V-F-L-R-L-P-R-G-T-L-L-Q-D-G-D-I-L-Q-D-E-T-N-G-N-L-I-R-I-A-A-K-P-E-P-V-L-T-A-V-A-Q-T-Q-L-L-L-M-R-A-A-Y-H-L-G-N-R-H-V-P-V-E-I-T-P-T-Y-L-R-L-S-P-D-T-V-L-R-T-M-L-E-H-M-G-L-E-I-T-A-E-I-L-P-F-Q-P-E-L-G-A-Y-G-H-H-H-P-H"} +{"text": "### FUNCTION Covalently attaches a chromophore to Cys residue In vitro is not seen to act as a chromophore lyase for ApcA1, ApcA2, ApcB, ApcD, ApcF, CpcB or PecB, the lyase activity is therefore unsure ### SEQUENCE -M-S-F-S-P-Q-L-V-N-L-G-N-Y-L-A-G-E-F-D-N-R-E-Q-A-L-G-E-P-I-W-F-V-H-L-R-L-W-Q-R-P-V-D-L-F-S-D-D-S-I-T-L-F-A-E-Q-A-N-I-V-N-L-D-R-P-Y-R-Q-R-I-L-R-L-M-P-A-P-D-S-E-T-G-L-Y-V-Q-Y-Y-M-P-K-N-P-S-A-L-I-G-A-G-R-H-P-D-L-L-K-T-L-T-P-Q-Q-L-E-L-L-P-G-C-V-L-S-V-S-Q-Q-T-V-A-P-N-S-Y-Q-F-T-A-S-P-L-P-N-T-C-C-T-F-S-Y-L-E-N-T-V-Q-V-S-L-G-F-A-V-T-E-T-E-L-H-T-Y-D-K-G-I-D-Q-E-T-G-K-A-T-W-G-A-I-V-G-P-Y-R-Y-T-K-R-E-Q-Y"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-V-K-R-V-Q-L-V-L-T-K-D-V-S-K-L-G-R-S-G-D-L-V-D-V-A-P-G-Y-A-R-N-Y-L-I-P-Q-S-L-A-T-H-A-T-P-G-I-L-K-Q-V-E-R-R-R-E-Q-E-R-Q-R-Q-L-E-L-R-Q-Q-A-L-E-Q-K-E-S-L-E-K-V-G-S-L-K-I-A-K-Q-V-G-E-N-E-A-I-F-G-T-V-T-S-Q-D-V-A-D-A-I-Q-A-A-T-S-Q-E-V-D-R-R-G-I-T-I-P-D-I-G-K-L-G-T-Y-K-A-E-I-K-L-F-S-D-V-T-A-Q-I-D-I-E-V-V-A-S"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-N-N-I-F-S-K-L-R-D-F-V-G-L-N-E-Q-V-E-Y-E-Y-Y-E-E-E-A-D-T-D-N-Y-Q-N-L-Y-Q-Q-E-N-P-Q-P-A-P-A-E-A-A-P-N-N-R-R-W-R-E-P-M-T-T-M-G-D-D-V-A-A-G-T-K-S-A-M-G-N-V-I-G-M-P-G-A-I-N-G-I-S-E-V-L-V-L-E-P-R-T-F-E-E-M-P-Q-A-I-Q-A-L-R-E-R-K-S-V-V-L-N-L-T-I-M-D-P-D-Q-A-Q-R-A-V-D-F-V-A-G-G-T-Y-A-L-D-G-H-Q-E-R-I-G-E-S-I-F-L-F-T-P-S-C-V-Q-V-S-T-Q-G-G-V-I-H-E-V-P-Q-P-P-A-R-P-A-R-P-A-S-T-N-P-P-A-W-G-N-E-T-N-R-M-A-Q"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-T-A-P-T-V-T-P-E-R-S-N-Q-T-V-R-K-T-Y-P-N-Y-K-V-I-V-L-N-D-D-F-N-T-F-Q-H-V-A-E-C-L-V-K-Y-I-P-G-M-T-G-D-L-A-W-D-L-T-N-Q-V-H-Y-E-G-Q-A-I-V-W-V-G-P-Q-E-P-A-E-L-Y-H-Q-Q-L-R-R-A-G-L-T-M-A-P-L-E-A-A"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-L-S-E-E-S-G-Y-L-V-Q-V-E-L-D-V-Q-D-C-F-F-E-S-F-P-E-A-A-Q-A-S-G-Y-M-D-S-Q-V-S-P-A-T-W-Q-D-W-F-H-R-W-L-E-I-L-D-S-S-L-P-P-A-P-S-Y-E-I-G-L-R-L-T-D-D-T-E-I-Q-A-I-N-A-Q-Y-R-Q-Q-N-K-P-T-D-V-L-A-F-A-A-L-E-V-D-L-P-Q-N-P-E-M-V-A-E-P-L-Y-L-G-D-I-V-V-S-I-N-T-A-Q-R-Q-A-G-Q-Q-E-H-S-L-S-T-E-L-A-W-L-T-A-H-G-L-L-H-L-L-G-W-D-H-P-D-E-E-S-L-I-A-M-L-Q-Q-Q-V-V-L-L-E-A-I-G-I-N-I-N-V-N-Y"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-A-Y-A-I-I-E-T-G-G-K-Q-V-R-V-E-P-G-R-F-Y-D-I-E-L-L-S-V-E-P-D-E-K-V-T-I-D-S-V-L-L-V-Q-N-D-G-E-V-T-I-G-Q-P-L-V-A-G-A-T-V-Q-G-T-V-L-R-H-L-R-G-R-K-V-L-V-Y-K-M-K-P-K-K-K-T-R-K-K-R-G-H-R-Q-E-I-T-R-L-L-I-D-S-I-T-L-N-G-T-V-L-T-A-P-T-A-T-E-E-T-A-D-A-T-P-D-T-E-T-A-A-E"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-S-V-A-Y-I-L-I-L-T-L-A-I-G-V-L-F-F-A-I-A-F-R-E-P-P-R-I-E-K-K-E-E-K"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-M-Q-V-L-S-I-Q-N-C-A-T-T-K-E-N-P-L-S-G-K-L-I-I-L-T-G-P-S-G-V-G-K-G-T-L-M-R-S-L-L-Q-R-H-P-E-L-Y-Y-S-V-S-A-T-T-R-P-P-R-P-G-E-V-N-G-E-S-Y-Y-F-V-S-R-S-K-F-E-E-L-I-A-Q-G-E-F-L-E-S-A-E-F-A-G-N-Y-Y-G-T-P-R-E-A-V-L-N-Q-V-Q-S-G-K-L-V-V-L-E-I-E-L-A-G-A-R-Q-I-R-T-S-F-P-E-A-L-S-I-F-I-L-P-P-S-F-E-E-L-E-N-R-I-R-G-R-G-Q-D-S-E-E-A-I-A-R-R-L-Q-R-A-K-E-E-I-Q-A-A-D-E-F-D-I-Q-I-V-N-D-D-F-E-A-A-L-Q-A-I-E-V-A-L-F-G"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-T-N-R-R-V-S-R-V-A-E-L-I-K-R-E-V-S-Q-M-L-I-N-G-I-K-D-D-R-V-G-T-G-M-V-S-V-T-D-V-D-V-S-G-D-L-Q-H-A-K-I-Y-V-S-I-Y-G-T-E-E-A-K-A-E-T-M-A-G-L-K-S-A-T-G-F-V-R-S-E-L-G-A-R-V-R-L-R-R-T-P-E-V-T-F-I-E-D-R-S-I-E-R-G-T-K-V-L-T-L-L-N-K-L-E-N-A-R-S-P-D-D-I-P-S-A-D-D-S-L-D-E-D"} +{"text": "### FUNCTION Involved in succinate export with YjjP Both proteins are required for export ### SEQUENCE -M-G-I-I-D-F-L-L-A-L-M-Q-D-M-I-L-S-A-I-P-A-V-G-F-A-M-V-F-N-V-P-H-R-A-L-P-W-C-A-L-L-G-A-L-G-H-G-L-R-M-L-M-M-S-A-G-F-N-I-E-W-S-T-F-M-A-S-L-L-V-G-S-I-G-I-Q-W-S-R-W-Y-L-A-H-P-K-V-F-T-V-A-A-V-I-P-M-F-P-G-I-S-A-Y-T-A-M-I-S-A-V-K-I-S-H-L-G-Y-S-E-P-M-M-I-T-L-L-T-N-F-L-K-A-S-S-I-V-G-A-L-S-I-G-L-S-V-P-G-L-W-L-Y-R-K-R-P-R-V"} +{"text": "### FUNCTION Involved in the degradation and recycling of damaged RNA It is itself a target for degradation by the ATP-dependent protease Lon ### SEQUENCE -M-T-T-V-H-S-I-A-D-P-C-D-P-E-V-S-P-T-N-N-R-H-L-T-V-S-Y-A-S-R-Y-P-D-Y-T-R-I-P-A-L-T-M-K-G-Q-W-L-E-A-A-G-F-A-T-G-T-E-V-D-V-R-V-M-N-G-C-I-V-L-T-A-Q-Q-P-Q-P-E-E-S-E-L-M-Q-S-L-R-Q-A-C-K-L-S-A-R-K-Q-K-Q-V-Q-A-F-I-S-V-M-A-G-S-K"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-T-H-D-N-K-L-Q-V-E-A-I-K-C-G-T-V-I-D-H-I-P-A-Q-V-G-F-K-L-L-S-L-F-K-L-T-E-T-D-Q-R-I-T-I-G-L-N-L-P-S-G-E-M-G-R-K-D-L-I-K-I-E-N-T-F-L-T-D-E-Q-V-N-Q-L-A-L-Y-A-P-Q-A-T-V-N-R-I-D-N-Y-D-V-V-G-K-S-R-P-S-L-P-E-R-I-N-N-V-L-V-C-P-N-S-N-C-I-S-H-A-E-P-V-S-S-S-F-A-V-K-K-R-A-N-D-I-A-L-K-C-K-Y-C-E-K-E-F-S-H-N-V-V-L-A-N"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-D-K-V-A-N-L-G-S-L-G-D-Q-V-N-V-K-A-G-Y-A-R-N-F-L-V-P-Q-G-K-A-V-P-A-T-K-K-N-V-E-Y-F-E-A-R-R-A-E-L-E-A-K-L-A-D-V-L-A-A-A-N-A-R-A-E-K-I-N-A-L-E-T-V-T-I-A-S-K-A-G-D-E-G-K-L-F-G-S-I-G-T-R-D-I-A-D-A-V-T-A-A-G-V-D-V-A-K-S-E-V-R-L-P-N-G-V-L-R-T-T-G-E-H-E-V-N-F-Q-V-H-S-E-V-F-A-K-V-I-I-N-V-V-A-E"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site During primosome assembly it facilitates the complex formation between PriA and DnaT ### SEQUENCE -M-T-N-R-L-T-L-S-G-T-V-C-R-A-P-L-R-K-V-S-P-S-G-I-P-H-C-Q-F-V-L-E-H-R-S-V-Q-E-E-A-G-F-H-R-Q-A-W-C-Q-M-P-V-I-V-S-G-H-E-N-Q-A-I-T-H-S-I-T-V-G-S-R-I-T-V-Q-G-F-I-S-C-H-K-A-K-N-G-L-S-K-M-V-L-H-A-E-Q-I-E-L-I-D-S-G-D"} +{"text": "### FUNCTION The phosphoenolpyruvate-dependent sugar phosphotransferase system , a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane The enzyme II UlaABC PTS system is involved in ascorbate transport ### SEQUENCE -M-K-L-R-D-S-L-A-E-N-N-S-I-R-L-Q-A-E-A-N-T-W-Q-E-A-V-K-I-G-V-D-L-L-V-A-A-D-V-V-E-P-R-Y-Y-Q-A-I-L-D-G-V-E-Q-F-G-P-Y-F-V-I-A-P-G-L-V-M-P-H-G-R-P-E-E-G-V-K-K-T-G-F-S-L-V-T-L-K-K-P-L-E-F-N-H-E-D-N-D-P-V-D-I-L-I-T-M-A-A-V-D-A-N-T-H-Q-E-V-G-I-M-Q-I-V-N-L-F-E-D-E-A-N-F-D-R-L-R-A-C-R-T-A-Q-E-V-L-D-L-I-D-R-T-N-A-A-A"} +{"text": "### FUNCTION Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress May require iron for activity ### SEQUENCE -M-Q-L-T-S-F-T-D-Y-G-L-R-A-L-I-Y-M-A-S-L-P-D-G-R-M-T-S-I-S-E-V-T-E-V-Y-D-V-S-R-N-H-M-V-K-I-I-N-Q-L-S-R-A-G-F-V-T-A-V-R-G-K-N-G-G-I-R-L-G-K-P-A-N-T-I-C-I-G-D-V-V-R-E-L-E-P-L-S-L-V-N-C-S-S-E-F-C-H-I-T-P-A-C-R-L-K-Q-A-L-S-K-A-V-Q-S-F-L-K-E-L-D-N-Y-T-L-A-D-L-V-E-E-N-Q-P-L-Y-K-L-L-L-V-E"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-V-L-Q-V-L-H-I-P-D-E-R-L-R-K-V-A-K-P-V-E-E-V-N-A-E-I-Q-R-I-V-D-D-M-F-E-T-M-Y-A-E-E-G-I-G-L-A-A-T-Q-V-D-I-H-Q-R-I-I-V-I-D-V-S-E-N-R-D-E-R-L-V-L-I-N-P-E-L-L-E-K-S-G-E-T-G-I-E-E-G-C-L-S-I-P-E-Q-R-A-L-V-P-R-A-E-K-V-K-I-R-A-L-D-R-N-G-N-P-F-E-L-E-A-D-G-L-L-A-I-C-I-Q-H-E-M-D-H-L-V-G-K-L-F-I-D-Y-L-S-P-L-K-Q-Q-R-I-R-Q-K-V-E-K-L-D-R-L-N-A-R-A"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-A-P-V-C-A-R-K-R-V-R-K-Q-V-S-D-G-V-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-G-W-A-T-A-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-R-C-A-D-A-V-K-E-Y-G-I-K-N-L-E-V-M-V-K-G-P-G-P-G-R-E-S-T-I-R-A-L-N-A-A-G-F-R-I-T-N-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-A-V-I-A-L-T-S-I-Y-G-V-G-K-T-R-S-K-A-I-L-A-A-A-G-I-A-E-N-V-K-I-S-E-L-S-E-E-Q-I-D-T-L-R-D-E-V-A-K-F-V-V-E-G-D-L-R-R-E-I-S-M-S-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-C-K-P-I-K-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-D-D-E-V-I-V-L-T-G-K-D-K-G-K-R-G-K-V-K-N-V-L-S-S-G-K-V-I-V-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-L-N-Q-P-G-G-I-V-E-K-E-A-A-I-Q-V-S-N-V-A-I-F-N-T-A-T-G-K-A-D-R-V-G-F-R-F-E-D-G-K-K-V-R-F-F-K-S-N-S-E-T-I-K"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-L-H-T-L-P-H-C-A-S-G-V-D-F-P-A-L-L-R-L-L-K-E-G-D-A-L-L-L-L-Q-D-G-V-T-V-A-I-E-G-N-R-F-L-E-S-L-R-D-A-P-I-T-V-Y-A-L-K-E-D-I-D-A-R-G-L-G-G-Q-I-S-D-S-V-V-R-V-D-Y-T-E-F-V-R-L-T-V-K-Y-A-N-Q-M-A-W"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-K-R-I-A-F-V-F-S-T-A-P-H-G-S-A-S-G-R-E-G-L-D-A-L-L-A-T-S-A-L-T-E-A-L-G-V-F-F-I-S-D-G-V-F-Q-L-L-P-G-Q-K-P-D-A-V-L-A-R-D-Y-I-A-T-F-K-L-F-D-L-Y-D-I-D-Q-C-W-I-C-A-A-S-L-R-E-R-G-L-E-N-V-N-F-V-V-N-A-T-P-L-E-P-V-A-L-R-R-E-L-G-N-Y-D-V-I-L-R-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-R-Y-A-I-M-V-T-G-P-A-Y-G-T-Q-Q-A-S-S-A-L-Q-F-A-H-A-L-L-N-E-G-H-E-L-A-S-V-F-F-Y-R-E-G-V-Y-N-A-N-L-L-T-S-P-A-S-D-E-Y-D-L-V-R-V-W-Q-K-L-N-T-Q-H-G-V-A-L-N-I-C-V-A-A-A-L-R-R-G-I-I-D-E-T-E-A-G-R-L-E-L-P-S-A-N-L-Q-P-G-F-T-L-S-G-L-G-A-L-A-E-A-S-L-T-C-D-R-V-V-Q-F"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-K-T-P-L-I-T-R-E-G-Y-E-T-L-K-Q-E-L-N-Y-L-W-R-E-E-R-P-E-V-T-K-K-V-T-W-A-A-S-L-G-D-R-S-E-N-A-D-Y-Q-Y-N-K-K-R-L-R-E-I-D-R-R-V-R-Y-L-T-K-C-M-E-N-L-K-I-V-D-Y-S-P-Q-Q-E-G-K-V-F-F-G-A-W-V-E-I-E-N-D-D-G-D-T-L-K-F-R-I-V-G-Y-D-E-I-F-G-R-K-D-Y-I-S-I-D-S-P-M-A-R-A-L-L-K-K-E-V-G-D-L-A-V-V-N-T-P-V-G-E-A-N-W-Y-V-N-A-I-E-Y-V-K"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-R-I-S-D-A-A-Q-A-H-F-A-K-L-L-A-N-Q-K-E-G-T-Q-I-R-V-F-V-I-N-P-G-T-P-N-A-E-C-G-V-S-Y-C-P-P-D-A-V-E-A-T-D-T-A-L-K-F-D-L-L-T-A-Y-V-D-E-L-S-A-P-Y-L-E-D-A-E-I-D-F-V-T-D-Q-L-G-S-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-A-D-D-A-P-L-M-E-R-V-E-Y-A-L-Q-S-Q-I-N-P-Q-L-A-G-H-G-G-R-V-S-L-M-E-I-T-D-E-G-Y-A-I-L-Q-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-E-G-I-E-K-Q-L-L-N-E-F-P-E-L-K-G-V-R-D-L-T-E-H-Q-R-G-E-H-S-Y-Y"} +{"text": "### FUNCTION May be involved in an alternative pathway for phosphopantetheinyl transfer and holo-ACP synthesis The native apo-protein substrate is unknown ### SEQUENCE -M-Y-Q-I-V-L-G-K-V-S-T-L-S-A-G-Q-L-P-D-A-L-I-A-Q-A-P-Q-G-V-R-R-A-S-W-L-A-G-R-V-L-L-S-R-A-L-S-P-L-P-E-M-V-Y-G-E-Q-G-K-P-A-F-S-A-G-T-P-L-W-F-N-L-S-H-S-G-D-T-I-A-L-L-L-S-D-E-G-E-V-G-C-D-I-E-V-I-R-P-R-D-N-W-R-S-L-A-N-A-V-F-S-L-G-E-H-A-E-M-E-A-E-R-P-E-R-Q-L-A-A-F-W-R-I-W-T-R-K-E-A-I-V-K-Q-R-G-G-S-A-W-Q-I-V-S-V-D-S-T-L-P-S-A-L-S-V-S-Q-C-Q-L-D-T-L-S-L-A-V-C-T-P-T-P-F-T-L-T-P-Q-T-I-T-K-A-L"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-A-Y-K-H-I-L-I-A-V-D-L-S-P-E-S-K-V-L-V-E-K-A-V-S-M-A-R-P-Y-N-A-K-I-S-L-I-H-V-D-V-N-Y-S-D-L-Y-T-G-L-I-D-V-N-L-G-D-M-Q-K-R-I-S-K-E-T-H-H-A-L-T-E-L-S-T-N-A-G-Y-P-I-T-E-T-L-S-G-S-G-D-L-G-Q-V-L-V-D-A-I-K-K-Y-D-M-D-L-V-V-C-G-H-H-Q-D-F-W-S-K-L-M-S-S-A-R-Q-L-I-N-T-V-H-V-D-M-L-I-V-P-L-R-D-E-E-E"} +{"text": "### FUNCTION Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE Its activity is ATP-independent ### SEQUENCE -M-R-N-Y-D-L-S-P-L-L-R-Q-W-I-G-F-D-K-L-A-N-A-L-Q-N-S-G-E-S-Q-S-F-P-P-Y-N-I-E-K-S-D-D-N-H-Y-R-I-T-L-A-L-A-G-F-R-Q-E-D-L-D-I-Q-L-E-G-T-R-L-T-V-K-G-T-P-E-Q-P-E-N-E-P-K-W-L-H-Q-G-L-V-M-Q-P-F-S-L-S-F-T-L-A-E-N-M-E-V-S-G-A-T-F-T-N-G-L-L-Y-I-D-L-T-R-N-E-P-E-T-I-P-P-Q-R-I-A-I-N-E-R-S-A-L-N-S"} +{"text": "### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-L-E-V-F-E-K-L-E-A-K-V-Q-Q-A-I-D-T-I-T-L-L-Q-M-E-I-E-E-L-K-E-K-N-N-S-L-T-Q-E-V-Q-S-A-Q-H-Q-R-E-E-L-E-R-E-N-N-F-L-K-E-Q-Q-S-G-W-Q-E-R-L-Q-A-L-L-G-R-M-E-E-V"} +{"text": "### FUNCTION This regulatory protein, when combined with SAM ### SEQUENCE -M-A-E-W-S-G-E-Y-I-S-P-Y-A-E-H-G-K-K-S-E-Q-V-K-K-I-T-V-S-I-P-L-K-V-L-K-I-L-T-D-E-R-T-R-R-Q-V-N-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-F-T-G-Q-P-L-P-D-D-A-D-L-R-K-E-R-S-D-E-I-P-E-A-A-K-E-I-M-R-E-M-G-I-D-P-E-T-W-E-Y"} +{"text": "### FUNCTION Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase ### SEQUENCE -M-L-N-Q-L-E-N-L-M-E-R-V-G-G-S-N-K-L-V-D-R-W-L-D-V-R-K-H-L-L-V-A-Y-Y-N-L-V-G-I-K-P-G-K-E-S-Y-M-R-L-N-E-K-A-L-D-D-F-C-Q-S-L-V-D-Y-L-S-A-G-H-F-S-I-Y-E-R-I-L-H-K-L-E-G-N-G-Q-L-L-H-A-A-K-I-W-P-L-L-E-D-N-T-Q-R-I-M-D-Y-Y-D-T-S-L-E-T-A-I-D-H-D-N-C-L-E-F-Q-Q-A-L-S-D-I-G-E-A-L-E-A-R-F-V-L-E-D-K-L-I-M-L-V-F-D-A-M-H-D-G-A-R-V-K-R-P-A"} +{"text": "### FUNCTION Binds zinc Could be an important component of the zinc-balancing mechanism ### SEQUENCE -M-K-R-N-N-K-S-A-I-A-L-I-A-L-S-L-L-A-L-S-S-G-A-A-F-A-G-H-H-W-G-N-N-D-G-M-W-Q-Q-G-G-S-P-L-T-T-E-Q-Q-A-T-A-Q-K-I-Y-D-D-Y-Y-T-Q-T-S-A-L-R-Q-Q-L-I-S-K-R-Y-E-Y-N-A-L-L-T-A-S-S-P-D-T-A-K-I-N-A-V-A-K-E-M-E-S-L-G-Q-K-L-D-E-Q-R-V-K-R-D-V-A-M-A-Q-A-G-I-P-R-G-A-G-V-G-Y-G-G-C-G-G-Y-G-G-G-Y-H-R-G-G-G-H-M-G-M-G-N-W"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-D-S-E-F-H-R-L-A-D-A-L-W-L-T-I-E-E-R-L-D-N-W-D-G-D-S-D-I-D-C-E-I-N-G-G-V-L-T-L-S-F-E-N-G-S-K-I-I-I-N-R-Q-E-P-L-H-Q-V-W-L-A-T-K-Q-G-G-Y-H-F-D-L-K-G-D-E-W-V-C-D-R-S-G-E-T-F-W-D-L-L-E-Q-A-A-T-Q-Q-A-G-E-K-V-S-F-R"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-S-E-L-L-L-V-F-V-I-G-L-I-V-L-G-P-Q-R-L-P-V-A-V-K-T-V-A-G-W-I-R-A-L-R-S-L-A-T-T-V-Q-N-E-L-T-Q-E-L-K-L-Q-E-F-Q-D-S-L-K-K-V-E-K-A-S-L-E-N-L-T-P-E-L-K-A-S-M-D-E-L-R-Q-A-A-E-S-M-K-R-T-Y-S-A-N-D-P-E-Q-A-S-D-E-A-H-T-I-H-N-P-V-V-K-G-N-E-T-Q-H-E-G-V-T-P-A-A-A-E-T-Q-A-S-A-P-E-Q-K-P-E-P-V-K-A-N-V-P-E-S-T-E-T-A-S-V-A-A-I-D-A-E-K-K-S-A-A-P-V-V-E-S-S-P-S-S-S-D-K-P"} +{"text": "### FUNCTION Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues , using respiratory chain electrons Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain ### SEQUENCE -M-R-L-T-V-K-Q-I-T-W-L-K-V-C-L-H-L-A-G-F-L-P-L-L-W-L-F-W-A-I-N-H-G-G-L-S-A-D-P-V-K-D-I-Q-H-F-T-G-R-T-A-L-K-F-L-L-A-T-L-L-V-S-P-L-A-R-Y-A-K-Q-P-L-L-I-R-T-R-R-L-L-G-L-W-C-F-V-W-A-T-L-H-L-T-S-Y-A-L-L-E-L-G-I-H-N-L-A-L-L-G-S-E-L-I-S-R-P-Y-L-T-L-G-I-I-S-W-L-V-L-L-A-L-T-L-T-S-T-Q-F-A-Q-R-K-L-G-K-R-W-Q-T-L-H-N-V-V-Y-L-V-A-I-L-A-P-I-H-Y-L-W-S-V-K-I-L-S-P-Q-P-V-I-Y-A-A-L-A-L-A-L-L-A-L-R-Y-R-K-F-R-Q-W-W-R"} +{"text": "### FUNCTION Catalyzes the decarboxylation of oxaloacetate coupled to Na translocation ### SEQUENCE -M-T-N-A-A-L-L-L-G-E-G-F-T-L-M-L-L-G-M-G-F-V-L-A-F-L-F-L-L-I-F-A-I-R-G-M-S-A-V-I-T-R-F-F-P-E-P-V-A-A-P-A-P-R-A-V-P-A-V-D-D-F-T-R-L-K-P-V-I-A-A-A-I-H-H-H-R-L-N-A"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-E-F-G-R-P-Q-R-V-A-Q-E-M-Q-K-E-I-A-L-I-L-Q-R-E-I-K-D-P-R-V-G-M-M-T-T-V-S-G-V-E-M-S-R-D-L-A-Y-A-K-V-F-V-T-F-L-N-D-Q-D-E-A-A-V-K-N-G-I-K-A-L-Q-E-A-S-G-F-I-R-S-L-L-G-K-A-M-R-L-R-I-V-P-E-L-T-F-F-Y-D-N-S-L-V-E-G-M-R-M-S-N-L-V-T-N-V-V-K-H-D-E-E-R-R-V-N-P-D-D-S-K-E-D"} +{"text": "### FUNCTION Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein ### SEQUENCE -M-L-E-R-I-K-V-C-F-T-E-S-I-Q-T-Q-I-A-A-A-E-A-L-P-D-A-I-S-R-A-A-M-T-L-V-H-S-L-L-N-G-N-K-I-L-C-C-G-N-G-T-S-A-A-N-A-Q-H-F-A-A-S-M-I-N-R-F-E-T-E-R-P-S-L-P-A-I-A-L-N-T-D-N-V-V-L-T-A-I-A-N-D-R-L-H-D-E-V-Y-A-K-Q-V-R-A-L-G-H-A-G-D-V-L-L-A-I-S-T-R-G-N-S-R-D-I-V-K-A-V-E-A-A-V-T-R-D-M-T-I-V-A-L-T-G-Y-D-G-G-E-L-A-G-L-L-G-P-Q-D-V-E-I-R-I-P-S-H-H-S-A-R-I-Q-E-M-H-M-L-T-V-N-C-L-C-G-L-I-D-N-T-L-F-P-H-Q-D-D"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-D-T-L-L-A-F-D-F-G-T-K-S-I-G-V-A-I-G-Q-R-I-T-G-T-A-R-P-L-P-A-I-K-A-Q-D-G-T-P-D-W-T-L-I-E-R-L-L-K-E-W-Q-P-D-E-I-I-V-G-L-P-L-N-M-D-G-T-E-Q-P-L-T-A-R-A-R-K-F-A-N-R-I-H-G-R-F-G-V-T-V-T-L-H-D-E-R-L-S-T-V-E-A-R-S-G-L-F-E-R-G-G-Y-R-A-L-N-K-G-K-V-D-S-A-S-A-V-I-I-L-E-S-Y-F-E-Q-G-Y"} +{"text": "### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-Q-P-N-D-I-T-F-F-Q-R-F-Q-N-D-I-L-A-G-R-K-T-I-T-I-R-D-A-S-E-S-H-F-K-A-G-D-A-L-R-V-G-R-F-E-D-D-G-Y-F-C-T-I-E-V-T-G-T-S-T-V-T-L-D-T-L-N-E-K-H-A-Q-Q-E-N-M-S-L-D-E-L-K-R-V-I-A-E-I-Y-P-N-Q-T-Q-F-Y-V-I-D-F-K-C-L"} +{"text": "### FUNCTION Acyl carrier protein ### SEQUENCE -M-N-M-D-I-E-A-R-V-K-K-V-I-T-S-C-I-A-V-D-V-D-S-I-N-G-Q-T-H-L-V-E-D-L-Y-A-D-S-L-D-L-I-D-I-V-F-G-L-S-E-E-F-D-I-S-C-N-E-N-D-L-P-D-M-T-T-F-A-D-I-C-R-V-V-K-K-S-L-E-S-R-V"} +{"text": "### FUNCTION Molecular chaperone required for SptP stabilization and secretion ### SEQUENCE -M-G-L-P-L-T-F-D-D-N-N-Q-C-L-L-L-L-D-S-D-I-F-T-S-I-E-A-K-D-D-I-W-L-L-N-G-M-I-I-P-L-S-P-V-C-G-D-S-I-W-R-Q-I-M-V-I-N-G-E-L-A-A-N-N-E-G-T-L-A-Y-I-D-A-A-E-T-L-L-F-I-H-A-I-T-D-L-T-N-I-Y-H-I-I-S-Q-L-E-S-F-V-N-K-Q-E-A-L-K-N-I-L-Q-E-Y-A-K-V"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-S-E-P-T-S-R-R-P-A-Y-A-R-L-L-D-R-A-V-R-I-L-A-V-R-D-H-S-E-Q-E-L-R-R-K-L-S-A-P-V-M-G-K-N-G-P-E-E-I-D-A-T-A-D-D-Y-E-R-V-I-A-W-C-H-E-H-H-Y-L-D-D-E-R-F-V-M-R-F-I-A-S-R-S-R-K-G-Y-G-P-A-R-I-R-Q-E-L-N-Q-K-G-I-S-R-E-S-T-E-K-A-M-R-E-C-E-I-D-W-S-E-M-A-R-E-Q-A-V-R-K-Y-G-E-P-L-P-S-N-F-S-E-K-V-K-V-Q-R-F-L-L-Y-R-G-Y-L-M-D-D-I-Q-Q-I-W-R-N-F-A-D"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-K-G-V-N-E-F-W-Q-Q-S-P-R-S-A"} +{"text": "### FUNCTION Exporter of O-acetylserine and cysteine ### SEQUENCE -M-T-P-M-L-L-S-A-F-W-T-Y-T-L-I-T-A-L-T-P-G-P-N-N-I-L-A-L-S-A-A-T-A-H-G-F-R-Q-S-I-R-V-L-A-G-M-S-L-G-F-L-V-V-M-L-L-C-A-G-I-A-F-S-L-A-V-I-D-P-A-I-I-H-L-L-S-W-V-G-A-A-Y-I-L-W-L-A-W-K-I-A-T-S-P-A-A-D-E-K-V-R-P-K-P-V-G-F-W-V-S-F-G-L-Q-F-V-N-V-K-I-I-L-Y-G-I-T-A-L-S-T-F-V-L-P-Q-T-Q-A-L-N-W-V-I-G-V-S-I-L-L-A-L-I-G-T-F-G-N-V-C-W-A-L-A-G-H-L-F-Q-R-A-F-R-H-Y-G-R-Q-L-N-I-I-L-A-L-L-L-V-Y-C-A-V-R-I-F-Y"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-D-Y-F-T-L-F-G-L-P-A-R-Y-Q-I-D-T-Q-A-L-S-F-R-F-Q-D-L-Q-R-Q-Y-H-P-D-K-F-A-N-G-T-Q-A-Q-Q-L-A-A-V-Q-Q-S-A-T-I-N-Q-A-W-Q-T-L-R-H-P-L-T-R-A-E-Y-L-L-S-L-H-G-F-D-L-A-S-E-Q-H-T-V-R-D-T-A-F-L-M-E-Q-L-T-L-R-E-E-L-D-D-I-E-Q-S-K-D-D-A-R-L-E-S-F-I-K-R-V-Q-K-M-F-D-A-R-L-Q-Q-M-V-E-Q-L-D-N-A-A-W-D-A-A-A-D-T-V-R-K-L-R-F-L-D-K-L-R-S-S-A-E-Q-L-E-E-K-L-L-D-F"} +{"text": "### FUNCTION A component of the bacterial microcompartment ### SEQUENCE -M-N-K-E-R-I-I-Q-E-F-V-P-G-K-Q-V-T-L-A-H-L-I-A-H-P-G-E-E-L-A-K-K-I-G-V-P-D-A-G-A-I-D-I-M-T-L-T-P-G-E-T-A-M-I-A-G-D-L-A-M-K-A-A-D-V-H-I-G-F-L-D-R-F-S-G-A-L-V-I-Y-G-T-V-G-A-V-E-E-A-L-L-Q-T-V-S-G-L-G-R-L-L-N-F-T-L-C-E-L-T-K-S"} +{"text": "### FUNCTION General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases ### SEQUENCE -M-K-M-F-V-P-A-V-V-F-A-A-L-A-S-A-S-A-W-A-N-N-G-D-T-A-Q-P-L-E-K-I-A-P-Y-P-Q-A-E-K-G-M-K-R-Q-V-I-T-L-T-P-Q-Q-D-E-S-T-L-K-V-E-L-L-I-G-Q-T-L-N-V-D-C-N-Q-H-R-L-G-G-T-L-E-T-K-T-L-E-G-W-G-Y-D-Y-Y-V-F-D-N-V-T-S-P-V-S-T-M-M-A-C-P-E-G-K-K-E-Q-K-F-V-T-A-W-L-G-E-D-G-M-L-R-Y-N-S-K-L-P-I-V-V-Y-T-P-A-N-V-D-V-K-Y-R-I-W-K-A-D-A-N-V-Q-N-A-I-A-R"} +{"text": "### FUNCTION Dephosphorylates Wzc Required for the extracellular polysaccharide colanic acid synthesis Probably involved in the export of colanic acid from the cell to medium Involved in protection of cells against contact-dependent growth inhibition ### SEQUENCE -M-F-N-K-I-L-V-V-C-V-G-N-V-C-R-S-P-T-A-E-R-L-L-K-R-F-H-P-S-L-T-V-A-S-A-G-L-G-A-L-V-G-K-G-A-D-P-A-A-A-S-V-A-S-A-H-D-L-S-L-E-N-H-C-A-R-Q-I-S-A-R-L-C-R-E-Y-D-L-I-L-T-M-E-K-R-H-I-A-A-L-C-D-I-A-P-E-M-R-S-K-V-M-L-F-G-H-W-D-S-E-R-E-I-P-D-P-Y-R-K-S-R-D-A-F-E-A-V-Y-T-L-L-E-R-S-A-R-Q-W-A-Q-A-L-N-A-E-Q-G-K-P"} +{"text": "### FUNCTION Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7 ### SEQUENCE -M-K-D-E-L-F-L-R-G-E-N-V-P-M-T-K-E-A-V-R-A-L-A-L-S-K-L-E-L-H-R-A-S-H-L-I-D-V-G-A-G-T-G-S-V-S-I-E-A-A-L-Q-F-P-S-L-Q-V-T-A-I-E-R-N-P-A-A-L-R-L-L-D-E-N-R-Q-R-F-A-C-G-N-I-D-I-L-P-G-E-A-P-M-T-I-T-G-K-A-D-A-V-F-M-G-G-S-G-G-H-L-T-A-L-I-D-W-A-M-G-H-L-H-P-G-G-R-L-V-M-T-F-I-L-Q-E-N-L-H-S-A-L-A-H-L-V-H-I-G-A-C-R-M-D-C-V-Q-L-Q-L-S-S-L-T-P-L-G-A-G-H-Y-F-K-P-N-N-P-V-F-V-I-A-C-Q-K-E-E-N-H-V-R-D-I"} +{"text": "### FUNCTION Part of the energy-coupling factor transporter complex CbiMNOQ involved in cobalt import ### SEQUENCE -M-K-K-T-L-M-L-L-A-M-V-V-A-L-V-I-L-P-F-F-I-N-H-G-G-E-Y-G-G-S-D-G-E-A-E-S-Q-I-Q-A-L-A-P-Q-Y-K-P-W-F-Q-P-L-Y-E-P-A-S-G-E-I-E-S-L-L-F-T-L-Q-G-S-L-G-A-A-V-I-F-Y-I-L-G-Y-C-K-G-K-Q-R-R-D-D-R-A"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-H-F-T-A-T-V-L-L-A-F-G-M-S-M-D-A-F-A-A-S-I-G-K-G-A-T-L-H-K-P-K-F-S-E-A-L-R-T-G-L-I-F-G-A-V-E-T-L-T-P-L-I-G-W-G-L-G-I-L-A-S-K-F-V-L-E-W-N-H-W-I-A-F-V-L-L-I-F-L-G-G-R-M-I-I-E-G-I-R-G-G-S-D-E-D-E-T-P-L-R-R-H-S-F-W-L-L-V-T-T-A-I-A-T-S-L-D-A-M-A-V-G-V-G-L-A-F-L-Q-V-N-I-I-A-T-A-L-A-I-G-C-A-T-L-I-M-S-T-L-G-M-M-I-G-R-F-I-G-P-M-L-G-K-R-A-E-I-L-G-G-V-V-L-I-G-I-G-V-Q-I-L-W-T-H-F-H-G"} +{"text": "### FUNCTION Activates the cell division inhibited by chromosomal DNA over-replication ### SEQUENCE -M-M-K-P-L-R-Q-Q-N-R-Q-I-I-S-Y-I-P-R-V-E-P-A-P-P-E-H-A-I-K-M-D-T-F-R-D-V-W-I-L-R-G-K-Y-V-A-F-V-L-T-G-E-S-F-Q-R-S-P-A-F-S-V-P-E-S-A-Q-R-W-A-N-Q-V-R-Q-E-N-E-I-A-D"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-G-G-K-R-V-Q-T-A-R-P-N-R-I-N-S-E-I-R-A-Q-E-V-R-L-T-G-L-E-G-E-Q-L-G-I-V-S-L-R-E-A-L-E-K-A-E-E-A-G-V-D-L-V-E-I-S-P-N-A-E-P-P-V-C-R-I-M-D-Y-G-K-F-L-Y-E-K-S-K-S-S-K-E-Q-K-K-K-Q-K-V-I-Q-V-K-E-I-K-F-R-P-G-T-D-E-G-D-Y-Q-V-K-L-R-S-L-I-R-F-L-E-E-G-D-K-A-K-I-T-L-R-F-R-G-R-E-M-A-H-Q-Q-I-G-M-E-V-L-N-R-V-K-N-D-L-Q-E-L-A-V-V-E-S-F-P-T-K-I-E-G-R-Q-M-I-M-V-L-A-P-K-K-K-Q"} +{"text": "### FUNCTION Participates in cysteine desulfuration mediated by SufS Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process ### SEQUENCE -M-A-A-L-P-D-K-E-K-L-L-R-N-F-T-R-C-A-N-W-E-E-K-Y-L-Y-I-I-E-L-G-Q-R-L-A-E-L-N-P-Q-D-R-N-P-Q-N-T-I-H-G-C-Q-S-Q-V-W-I-V-M-R-R-N-A-N-G-I-I-E-L-Q-G-D-S-D-A-A-I-V-K-G-L-M-A-V-V-F-I-L-Y-H-Q-M-T-A-Q-D-I-V-H-F-D-V-R-P-W-F-E-K-M-A-L-T-Q-H-L-T-P-S-R-S-Q-G-L-E-A-M-I-R-A-I-R-A-K-A-A-T-L-S"} +{"text": "### FUNCTION Curlin is the structural subunit of the curli Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius Curli can bind to fibronectin The minor subunit is the nucleation component of curlin monomers ### SEQUENCE -M-K-N-K-L-L-F-M-M-L-T-I-L-G-A-P-G-I-A-T-A-T-N-Y-D-L-A-R-S-E-Y-N-F-A-V-N-E-L-S-K-S-S-F-N-Q-A-A-I-I-G-Q-V-G-T-D-N-S-A-R-V-R-Q-E-G-S-K-L-L-S-V-I-S-Q-E-G-E-N-N-R-A-K-V-D-Q-A-G-N-Y-N-F-A-Y-I-E-Q-T-G-N-A-N-D-A-S-I-S-Q-S-A-Y-G-N-S-A-A-I-I-Q-K-G-S-G-N-K-A-N-I-T-Q-Y-G-T-Q-K-T-A-V-V-V-Q-K-Q-S-H-M-A-I-R-V-T-Q-R"} +{"text": "### FUNCTION Molecular chaperone required for SopB/SigD stabilization and secretion ### SEQUENCE -M-E-S-L-L-N-R-L-Y-D-A-L-G-L-D-A-P-E-D-E-P-L-L-I-I-D-D-G-I-Q-V-Y-F-N-E-S-D-H-T-L-E-M-C-C-P-F-M-P-L-P-D-D-T-L-T-L-Q-H-F-L-R-L-N-Y-A-S-A-V-T-I-G-A-D-A-D-N-T-A-L-V-A-L-Y-R-L-P-Q-T-S-T-E-E-E-A-L-T-G-F-E-L-F-I-S-N-V-K-Q-L-K-E-H-Y-A"} +{"text": "### FUNCTION Required for spatial organization of the terminus region of the chromosome during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-Q-L-E-N-L-E-S-G-W-K-W-K-Y-L-V-K-K-H-R-E-G-E-L-I-T-R-Y-V-E-A-S-A-A-Q-E-A-V-N-L-L-L-A-L-E-N-E-P-V-R-V-N-V-W-I-D-R-H-M-N-P-A-L-L-N-R-M-R-Q-T-I-R-A-R-R-K-R-H-F-N-A-E-H-Q-H-T-R-K-K-S-I-D-L-E-F-M-V-W-Q-R-L-A-G-L-A-Q-R-R-G-K-T-L-S-E-T-I-V-Q-L-I-E-D-A-E-H-K-E-K-Y-A-T-Q-M-T-T-L-K-Q-D-L-Q-A-L-L-G-K-K"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-I-G-L-R-P-A-F-S-T-M-L-F-L-L-L-L-T-G-G-V-Y-P-L-L-T-T-A-L-G-Q-W-W-F-P-W-Q-A-N-G-S-L-I-H-K-D-N-L-I-R-G-S-A-L-I-G-Q-S-F-T-A-A-G-Y-F-H-G-R-P-S-A-T-A-D-T-P-Y-N-P-L-A-S-G-G-S-N-L-A-A-S-N-P-E-L-D-A-Q-I-Q-A-R-V-A-A-L-R-A-A-N-P-Q-A-S-S-A-V-P-V-E-L-T-T-A-S-A-S-G-L-D-N-N-L-T-P-G-A-A-A-W-Q-I-P-R-V-A-A-A-R-Q-L-P-V-E-Q-V-A-Q-L-V-A-E-Y-T-H-R-P-L-A-S-F-L-G-Q-P-V-V-N-I-V-E-L-N-L-A-L-D-A-L-Q-G-H-R-A-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-Q-V-I-L-D-L-Q-L-A-C-E-N-H-A-G-L-P-D-E-A-Q-F-Q-R-W-L-D-G-V-I-P-Q-F-Q-E-E-A-E-V-T-I-R-L-V-D-E-A-E-S-H-D-L-N-L-T-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-A-P-P-G-I-E-M-P-L-L-G-D-L-I-I-C-R-Q-V-V-E-Q-E-A-Q-E-Q-S-K-P-L-E-A-H-W-A-H-M-V-V-H-G-S-L-H-L-L-G-Y-D-H-I-D-D-D-E-A-E-E-M-E-S-L-E-T-E-I-M-L-A-M-G-Y-E-D-P-Y-I-A-E-K-I-A-E"} +{"text": "### FUNCTION Together with LptD, is involved in the assembly of lipopolysaccharide at the surface of the outer membrane Required for the proper assembly of LptD Binds LPS and may serve as the LPS recognition site at the outer membrane ### SEQUENCE -M-R-Y-L-V-T-L-L-L-S-L-A-V-L-V-T-A-G-C-G-W-H-L-R-S-T-T-Q-V-P-A-S-M-K-T-M-I-L-D-S-G-D-P-N-G-P-L-S-R-A-V-R-N-Q-L-R-L-N-N-V-N-L-L-D-K-D-T-T-R-K-D-V-P-S-L-R-L-G-T-V-T-I-S-Q-D-T-A-S-V-F-Q-D-G-Q-T-A-E-Y-Q-M-V-M-T-V-N-A-S-V-L-I-P-G-H-D-I-Y-P-I-S-T-K-V-Y-R-S-F-F-D-N-P-Q-M-A-L-A-K-D-N-E-Q-A-M-I-V-Q-E-M-Y-D-K-A-A-E-Q-L-I-R-K-L-A-S-V-R-A-A-D-I-Q-A-T-K-E-E-A-T-A-D-N-E-T-A-A-P-A-S-T-P-A-R-V-S-T-T-L-S-N"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-A-T-A-Q-Q-L-E-F-L-K-N-S-I-K-S-I-Q-D-Y-P-K-P-G-I-L-F-R-D-V-T-S-L-L-E-D-P-K-A-Y-A-L-S-I-E-L-L-V-E-R-Y-K-N-A-G-I-T-K-V-V-G-T-E-A-R-G-F-L-F-G-A-P-V-A-L-G-L-G-V-G-F-V-P-V-R-K-P-R-K-L-P-R-E-T-I-A-E-T-Y-E-L-E-Y-G-T-D-Q-L-E-I-H-V-D-A-I-K-P-G-D-N-V-L-V-V-D-D-L-L-A-T-G-G-T-I-E-A-T-V-K-L-I-R-R-L-G-G-K-V-T-D-A-A-F-I-I-N-L-F-D-L-G-G-E-Q-R-L-E-K-Q-G-I-T-C-Y-S-L-M-P-F-P-G-H"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-P-A-A-R-H-R-A-R-E-C-A-V-Q-A-L-Y-S-W-Q-L-S-Q-N-D-I-A-D-V-E-Y-Q-F-L-A-E-Q-D-V-K-D-V-D-V-L-Y-F-R-E-L-L-S-G-V-A-T-N-S-A-Y-L-D-G-L-M-K-P-Y-L-S-R-L-L-E-E-L-G-Q-V-E-K-A-V-L-R-I-A-L-F-E-L-S-K-R-S-D-V-P-Y-K-V-A-I-N-E-A-I-E-L-A-K-T-F-G-A-E-D-S-H-K-F-V-N-G-V-L-D-K-A-A-P-V-I-R-P-N-K-K"} +{"text": "### FUNCTION Regulates secA expression by translational coupling of the secM secA operon Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation ### SEQUENCE -M-S-G-I-L-T-R-W-R-Q-L-G-R-R-Y-F-W-P-H-L-L-L-G-M-V-A-A-S-F-G-L-P-A-L-S-N-A-A-E-T-N-T-P-A-R-T-T-A-S-T-A-S-K-V-N-F-S-H-L-A-L-L-E-A-S-N-R-R-P-N-F-T-V-D-Y-W-H-Q-H-A-I-R-T-V-I-R-H-L-S-F-A-M-A-P-Q-T-L-P-V-A-D-A-P-S-P-L-Q-A-H-H-I-A-L-L-N-T-L-S-A-M-L-T-Q-E-G-T-P-P-A-I-V-R-R-L-S-L-A-Y-F-A-P-Q-T-A-F-S-I-P-A-W-I-S-Q-A-Q-G-I-R-A-G-P-Q-R-L-S"} +{"text": "### FUNCTION Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall gene cluster Acts by binding directly to DNA May also regulate the expression of genes outside the dcw cluster ### SEQUENCE -M-F-R-G-A-T-L-V-N-L-D-S-K-G-R-L-T-V-P-T-R-Y-R-E-Q-L-I-E-S-A-T-G-Q-I-V-C-T-I-D-I-H-H-P-C-L-L-L-Y-P-L-P-E-W-E-I-I-E-Q-K-L-S-R-L-S-S-M-N-P-V-E-R-R-V-Q-R-L-L-L-G-H-A-S-E-C-Q-M-D-G-A-G-R-L-L-I-A-P-V-L-R-Q-H-A-G-L-T-K-E-V-M-L-V-G-Q-F-N-K-F-E-L-W-D-E-T-T-W-Y-Q-Q-V-K-E-D-I-D-A-E-Q-S-A-T-E-T-L-S-E-R-L-Q-D-L-S-L"} +{"text": "### FUNCTION Overproduction of CaiE stimulates the activity of CaiB and CaiD ### SEQUENCE -M-S-Y-Y-A-F-E-G-L-I-P-V-V-H-P-D-A-F-V-H-P-S-A-V-L-I-G-D-V-I-V-G-A-G-V-Y-I-G-P-L-A-S-L-R-G-D-Y-G-R-L-I-L-E-A-G-S-N-L-Q-D-G-C-I-M-H-G-Y-C-D-T-D-T-I-V-H-E-N-G-H-I-G-H-G-A-I-L-H-G-C-V-V-G-R-D-A-L-V-G-M-N-S-V-I-M-D-G-A-V-I-G-E-E-S-I-V-A-A-M-S-F-V-K-A-G-F-Q-G-E-A-R-Q-L-L-V-G-S-P-A-R-V-L-R-Q-V-T-D-Q-E-L-Y-W-K-R-L-N-T-K-E-Y-Q-D-L-A-I-R-C-R-T-G-L-S-E-T-K-P-L-T-Q-V-E-E-N-R-P-R-L-K-G-T-T-D-V-K-P-K-S-A-Q"} +{"text": "### FUNCTION Catalyzes the decarboxylation of oxaloacetate coupled to Na translocation ### SEQUENCE -M-N-E-A-V-L-L-G-E-G-F-T-L-M-F-L-G-M-G-F-V-L-S-F-L-F-L-L-I-F-A-I-R-G-M-S-A-V-I-T-R-F-F-P-E-P-V-A-A-P-A-P-R-A-V-P-A-V-D-D-F-T-R-L-K-P-V-I-A-A-A-I-H-H-H-R-L-N-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-V-K-L-A-F-P-R-E-L-R-L-L-T-P-S-H-F-T-F-V-F-Q-Q-P-Q-R-A-G-T-P-Q-I-T-I-L-G-R-L-N-E-L-G-H-P-R-I-G-L-T-V-A-K-K-H-V-K-R-A-H-E-R-N-R-I-K-R-L-T-R-E-S-F-R-L-H-Q-H-A-L-P-S-M-D-F-V-V-L-V-K-K-G-V-A-D-L-D-N-R-A-L-T-E-A-L-E-K-L-W-R-R-H-C-R-Q-A-P-A-S"} +{"text": "### FUNCTION Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE Its activity is ATP-independent ### SEQUENCE -M-R-N-S-D-L-A-P-L-Y-R-S-A-I-G-F-D-R-L-F-N-L-L-E-S-G-Q-N-Q-S-N-G-G-Y-P-P-Y-N-V-E-L-V-D-E-N-N-Y-R-I-A-I-A-V-A-G-F-A-E-Q-E-L-E-I-T-T-Q-D-N-L-L-I-V-R-G-S-H-A-N-E-P-A-Q-R-T-Y-L-Y-Q-G-I-A-E-R-N-F-E-R-K-F-Q-L-A-E-H-I-K-I-K-G-A-N-L-V-N-G-L-L-Y-I-D-L-E-R-L-V-P-E-S-L-K-P-R-R-I-E-I-K"} +{"text": "### FUNCTION Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE Its activity is ATP-independent ### SEQUENCE -M-R-N-Y-D-L-S-P-L-L-R-Q-W-I-G-F-D-K-L-A-S-T-M-Q-G-G-Q-E-P-Q-G-F-P-P-Y-N-I-E-K-T-D-D-N-H-Y-R-I-S-L-A-L-A-G-F-K-Q-S-E-L-D-I-E-V-E-G-P-R-L-T-V-R-G-K-P-T-P-V-E-K-Q-V-E-Y-L-H-Q-G-L-V-R-K-E-F-S-L-T-F-T-L-A-E-H-L-N-V-D-N-A-Q-F-E-N-G-L-L-H-I-D-L-L-R-Q-V-P-E-A-L-Q-P-Q-R-I-A-I-G-S-A-T-P-Q-E-R-Q-V-L-E-S-P-E-A-P-D-Q-Q"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-A-Y-K-H-I-L-I-A-V-D-L-S-P-E-S-K-V-L-V-E-K-A-V-S-M-A-K-P-Y-N-A-K-V-S-L-I-H-V-D-V-N-Y-S-D-L-Y-T-G-L-I-D-V-N-L-G-D-M-Q-K-R-I-S-E-E-T-H-N-A-L-T-E-L-S-Q-N-A-G-Y-P-V-E-Q-T-L-S-G-S-G-D-L-G-Q-V-L-V-D-A-I-K-K-Y-D-I-D-L-V-L-C-G-H-H-Q-D-F-W-S-K-L-M-S-S-A-R-Q-L-I-N-T-V-H-V-D-M-L-I-V-P-L-R-D-D-E-N-G-E-D-D"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-I-G-W-A-Q-L-L-I-I-A-V-I-V-V-L-L-F-G-T-N-K-L-R-T-L-G-S-D-L-G-A-S-I-K-G-F-K-K-A-M-G-D-D-S-Q-T-P-P-T-N-V-D-K-T-S-N-D-A-D-F-A-K-S-I-T-E-K-Q-Q-P-V-A-K-A-E-E-S-K-S-H-E-K-E-Q-G"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase , probably by partially suppressing pausing In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho May be required to overcome a kinetic limitation of Rho to function at certain terminators Also involved in ribosomal RNA transcriptional antitermination ### SEQUENCE -M-S-E-A-P-K-K-R-W-Y-V-V-Q-A-F-S-G-F-E-G-R-V-A-Q-S-L-R-E-H-I-K-L-H-D-M-E-E-L-F-G-E-V-M-V-P-T-E-E-V-V-E-I-R-G-G-Q-R-R-K-S-E-R-K-F-F-P-G-Y-V-L-V-Q-M-V-M-N-D-A-S-W-H-L-V-R-S-V-P-R-V-M-G-F-I-G-G-T-S-D-R-P-A-P-I-S-D-K-E-V-D-A-I-M-N-R-L-Q-Q-V-G-D-K-P-R-P-K-T-L-F-E-P-G-E-L-V-R-V-S-D-G-P-F-A-D-F-N-G-V-V-E-E-V-D-Y-E-K-S-R-L-K-V-S-V-S-I-F-G-R-A-T-P-V-E-L-D-F-S-Q-V-E-K-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-Q-A-Y-V-K-L-Q-V-A-A-G-M-A-N-P-S-P-P-V-G-P-A-L-G-Q-Q-G-V-N-I-M-E-F-C-K-A-F-N-A-K-T-E-S-I-E-K-G-L-P-I-P-V-V-I-T-V-Y-S-D-R-S-F-T-F-V-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-I-K-S-G-S-G-V-P-N-K-D-K-V-G-K-V-T-S-A-Q-V-R-E-I-A-E-T-K-A-A-D-M-T-G-S-D-V-D-A-M-M-R-S-I-E-G-T-A-H-S-M-G-L-V-V-E-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-Q-G-K-Q-A-I-V-A-E-V-K-E-V-A-K-G-A-L-S-A-V-V-A-D-S-R-G-V-T-V-D-K-M-T-E-L-R-R-A-G-R-E-A-G-V-H-M-Q-V-V-R-N-T-L-L-R-R-I-V-E-G-T-P-F-E-C-L-K-D-T-F-V-G-P-T-L-I-A-F-S-A-E-H-P-G-A-A-A-R-L-F-K-A-F-A-K-D-N-A-K-F-E-V-K-A-A-A-F-E-G-E-L-I-P-A-A-Q-I-D-R-L-A-T-L-P-T-Y-E-E-A-I-A-R-L-M-G-T-M-K-E-A-A-A-G-K-L-V-R-T-L-A-A-L-R-D-Q-K-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-T-I-T-K-D-Q-I-L-E-G-V-A-A-L-S-V-M-E-I-V-E-L-I-S-A-M-E-E-K-F-G-V-S-A-A-A-V-A-A-G-P-A-A-A-V-E-A-A-E-E-Q-T-E-F-D-V-V-L-A-S-F-G-E-N-K-V-A-V-I-K-A-V-R-G-A-T-G-L-G-L-K-E-A-K-D-L-V-E-S-A-P-A-V-L-K-E-G-V-N-K-D-E-A-E-T-L-K-K-S-L-E-E-A-G-A-S-V-E-I-K"} +{"text": "### FUNCTION Electron-transport protein of unknown function ### SEQUENCE -M-G-K-T-L-M-A-L-I-T-A-A-L-L-S-T-S-S-L-V-M-A-A-S-V-A-D-D-M-E-T-I-A-E-H-Y-G-K-V-L-K-A-D-S-T-A-V-I-K-Q-D-L-Q-A-M-R-V-A-A-V-D-A-Q-K-G-I-P-T-K-L-K-S-K-V-E-D-S-P-E-M-K-D-F-R-H-G-M-D-V-L-I-G-E-I-D-G-A-L-A-L-A-D-Q-G-K-L-D-E-A-K-Q-A-A-Q-D-F-K-D-T-R-N-T-Y-H-K-K-Y-R"} +{"text": "### FUNCTION Activates ribosomal RNA transcription Plays a direct role in upstream activation of rRNA promoters ### SEQUENCE -M-F-E-Q-R-V-N-S-D-V-L-T-V-A-T-V-N-S-Q-D-Q-V-T-Q-K-P-L-R-D-S-V-K-Q-A-L-K-N-Y-F-A-Q-L-N-G-Q-D-V-S-D-L-Y-E-L-V-L-A-E-V-E-Q-P-L-L-D-M-V-M-Q-Y-T-R-G-N-Q-T-R-A-A-L-M-M-G-I-N-R-G-T-L-R-K-K-L-K-K-Y-G-M-N"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-T-Q-D-Y-K-L-Q-V-E-A-I-K-C-G-T-V-I-D-H-I-P-A-Q-I-G-F-K-L-L-S-L-F-K-L-T-A-T-D-Q-R-I-T-I-G-L-N-L-P-S-K-R-S-G-R-K-D-L-I-K-I-E-N-T-F-L-T-E-Q-Q-A-N-Q-L-A-M-Y-A-P-D-A-T-V-N-R-I-D-N-Y-E-V-V-K-K-L-T-L-S-L-P-E-R-I-D-A-V-L-T-C-P-N-S-N-C-I-S-H-N-E-P-V-D-S-S-F-T-V-K-A-Q-R-G-E-I-S-L-K-C-K-Y-C-E-K-E-F-D-H-L-T-V-L-H-A-D"} +{"text": "### FUNCTION Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein ### SEQUENCE -M-L-E-R-I-K-G-C-F-T-E-S-I-Q-T-Q-I-A-A-A-E-A-L-P-D-A-I-S-C-A-A-M-A-L-V-Q-S-L-L-N-G-N-K-I-L-C-C-G-N-G-T-S-A-A-N-A-Q-H-F-A-A-S-M-I-N-R-F-E-T-E-R-P-S-L-P-A-I-A-L-N-A-D-N-V-V-L-T-A-I-T-N-D-R-L-H-D-E-V-Y-A-K-Q-V-R-A-L-G-Q-A-G-D-V-L-L-A-I-S-T-R-G-N-S-R-D-I-V-K-A-V-E-A-A-V-T-R-D-M-T-I-V-A-L-T-G-Y-D-G-G-E-L-A-G-L-L-G-Q-L-D-V-E-I-R-I-P-S-H-R-G-A-R-V-Q-E-L-H-M-L-T-V-N-C-L-C-D-L-I-D-N-T-L-F-P-H-Q-N-D"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-P-G-M-I-E-R-Y-S-A-T-I-T-N-A-A-G-T-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-V-L-L-N-V-E-A-P-Q-E-A-I-D-E-L-E-T-N-F-R-F-N-D-A-V-I-R-S-M-V-M-R-V-K-H-A-V-T-E-A-S-P-M-V-K-A-K-D-E-R-R-E-R-H-D-F-A-S-E-A-N-D-D-S-E-A-G-D-S-E-E"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-V-T-T-N-R-L-V-L-S-G-T-V-C-K-T-P-V-R-K-V-S-P-S-G-I-P-H-C-Q-F-V-L-E-H-R-S-T-Q-Q-E-A-G-F-S-R-Q-T-W-C-R-M-P-I-V-V-S-G-Q-Q-S-Q-A-L-T-H-S-I-T-V-G-S-Q-L-T-V-E-G-F-I-S-C-H-Q-G-R-N-G-L-N-K-L-V-L-H-A-E-Q-I-E-F-I-D-S-G-D"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-Y-F-R-R-R-K-F-C-R-F-T-A-E-G-V-V-E-I-D-Y-K-D-I-A-T-L-K-N-Y-I-T-E-S-G-K-I-V-P-S-R-I-T-G-T-R-A-K-Y-Q-R-Q-L-A-R-C-I-K-R-A-R-Y-L-S-L-L-P-Y-T-D-R-H-Q"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-D-K-V-A-N-L-G-S-L-G-D-Q-V-N-V-K-A-G-Y-A-R-N-F-L-V-P-Q-G-K-A-V-P-A-T-K-K-N-V-E-F-F-E-A-R-R-A-E-L-E-A-K-L-A-D-V-L-A-A-A-E-A-R-A-T-K-I-N-E-L-V-S-V-T-I-S-S-K-A-G-D-E-G-K-L-F-G-S-I-G-T-R-D-I-A-D-A-V-T-A-A-G-V-E-V-A-K-S-E-V-R-L-P-N-G-V-L-R-T-A-G-E-H-E-V-H-F-Q-V-H-S-D-V-F-A-K-L-N-V-V-V-V-P-E-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-R-N-P-A-K-Q-E-D-L-I-K-A-F-K-A-L-L-K-E-E-K-F-S-S-Q-G-E-I-V-L-A-L-Q-E-E-G-F-E-N-I-N-Q-S-K-V-S-R-M-L-T-K-F-G-A-V-R-T-R-N-A-K-M-E-M-V-Y-C-L-P-A-E-L-G-V-P-T-T-S-S-P-L-K-N-L-V-L-D-V-D-Y-N-D-S-V-V-V-I-N-T-S-P-G-A-A-Q-L-I-A-R-L-L-D-S-L-G-K-A-E-G-I-L-G-S-I-A-G-D-D-T-I-F-T-T-P-A-R-G-F-T-V-K-Q-L-H-E-A-I-L-R-L-F-E-Q-E-L"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-K-Q-I-P-M-T-V-R-G-A-D-K-L-R-E-E-L-D-Y-L-K-G-V-R-R-P-K-I-I-S-D-I-A-D-A-R-E-H-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-Q-Q-G-F-C-E-G-R-I-Q-E-I-E-A-K-L-S-N-A-Q-V-I-D-I-T-K-M-P-N-N-G-R-V-I-F-G-A-T-V-R-V-L-N-L-N-T-E-E-E-Q-N-Y-R-I-V-G-D-D-E-A-D-F-K-Q-N-L-I-S-V-N-S-P-I-A-R-G-L-I-G-K-E-V-D-D-V-V-V-I-H-T-P-G-G-E-V-E-Y-E-I-L-S-V-E-Y-V"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-G-L-S-T-L-E-Q-K-L-T-E-I-I-S-A-P-V-E-A-L-G-Y-E-L-V-G-I-E-F-I-R-G-R-Q-S-T-L-R-I-Y-I-D-S-D-D-G-I-T-V-D-A-C-A-D-V-S-H-Q-V-S-A-V-L-D-V-E-D-P-I-T-V-A-Y-N-L-E-V-S-S-P-G-L-D-R-P-M-F-T-A-E-H-Y-T-R-Y-L-G-E-E-V-T-L-V-L-R-M-A-M-Q-N-R-R-K-W-Q-G-I-I-K-A-V-D-G-E-M-I-T-V-T-V-D-G-K-D-E-V-F-A-L-S-N-I-Q-K-A-N-L-V-P-H-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-E-F-S-R-S-Q-R-V-S-Q-E-M-Q-K-E-I-A-L-I-L-Q-R-E-I-K-D-P-R-V-G-M-A-T-V-S-G-I-E-L-S-R-D-L-A-Y-A-K-V-F-V-T-F-L-N-V-L-T-D-N-A-D-P-D-T-V-K-N-G-I-K-A-L-Q-D-A-S-G-Y-I-R-T-L-L-G-K-A-M-R-L-R-I-V-P-E-L-T-F-A-Y-D-N-S-L-I-E-G-M-R-M-S-N-L-V-S-N-V-I-K-N-D-V-E-R-Q-V-N-P-G-S-D-E-E-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-S-V-E-A-K-A-K-I-V-A-D-F-G-R-G-T-N-D-T-G-S-S-E-V-Q-V-A-L-L-T-A-Q-I-N-H-L-Q-G-H-F-S-E-H-K-K-D-H-H-S-R-R-G-L-L-R-M-V-S-T-R-R-K-L-L-D-Y-L-K-R-Q-D-V-A-R-Y-A-S-L-I-E-R-L-G-L-R-R"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-E-S-E-Q-I-Q-V-N-C-P-T-C-G-K-V-V-I-W-G-E-Q-S-P-F-R-P-F-C-C-K-R-C-Q-L-I-D-L-G-E-W-A-D-E-E-K-R-I-P-S-D-T-E-L-S-D-S-D-E-W-S-E-E-D-P-L-K-H"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-G-K-L-T-L-L-L-L-V-L-L-G-W-L-Q-Y-S-L-W-L-G-K-N-G-I-H-D-F-V-R-V-K-E-D-V-A-A-Q-E-A-N-N-S-T-L-K-A-R-N-D-Q-L-F-A-E-I-D-D-L-N-G-G-Q-E-A-I-E-E-R-A-R-N-E-L-G-M-I-K-P-G-E-S-F-Y-R-L-V-P-D-Q-S-R-R-N-A-G-T-P-S-T-Q-N-N-A-Q"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-K-Q-L-N-P-A-V-P-D-Q-P-I-V-L-G-K-M-G-S-T-Y-G-I-R-G-W-L-R-V-F-S-S-T-E-N-A-E-S-I-F-D-Y-Q-P-W-F-I-Q-Q-A-G-K-W-Q-H-V-E-L-E-D-W-K-R-H-S-Q-D-L-I-I-K-V-K-G-V-D-D-R-E-A-A-N-L-L-T-N-C-E-I-I-V-D-S-T-Q-L-P-A-L-E-E-D-D-Y-Y-W-K-D-L-M-G-C-Q-V-V-T-T-T-G-Y-E-L-G-K-I-I-D-M-M-E-T-G-S-N-D-V-M-V-V-K-A-N-L-K-D-A-F-G-M-K-E-R-L-V-P-F-L-H-G-Q-V-I-K-K-V-D-L-T-A-Q-R-V-E-V-D-W-D-P-G-F"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-N-I-I-K-Q-I-E-Q-E-Q-M-K-Q-D-V-P-A-F-R-P-G-D-S-V-E-V-K-V-W-V-V-E-G-S-K-K-R-L-Q-A-F-E-G-V-V-I-A-I-R-N-R-G-L-H-S-A-F-T-V-R-K-I-S-N-G-E-G-V-E-R-V-F-Q-T-H-S-P-V-I-D-S-I-T-V-K-R-R-G-A-V-R-Q-A-K-L-Y-Y-L-R-E-R-T-G-K-S-A-R-I-K-E-R-L-G"} +{"text": "### FUNCTION Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP ### SEQUENCE -M-N-F-L-A-H-L-H-L-A-A-L-A-D-S-S-L-L-G-N-L-L-A-D-F-V-R-G-N-P-Q-G-E-Y-P-P-E-I-V-A-G-I-M-M-H-R-R-V-D-V-M-T-D-T-L-P-L-V-K-E-A-R-T-Y-F-S-A-D-Y-R-R-V-S-P-I-T-L-D-V-L-W-D-H-F-L-A-R-H-W-D-Q-L-V-P-N-C-T-L-P-D-F-L-Q-H-A-Q-S-Q-I-L-P-H-L-P-H-T-P-A-R-F-Q-S-L-N-A-Y-L-W-S-E-R-W-L-E-R-Y-A-E-L-P-F-I-A-D-V-L-Q-G-M-A-N-R-R-P-K-L-A-A-L-A-G-S-F-Y-A-I-E-Q-H-Y-Q-P-L-E-D-L-F-L-T-F-Y-P-T-M-M-R-Q-A-Q-H-K-Q-I"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-A-A-V-D-T-K-V-I-D-S-R-L-V-S-D-G-S-Q-V-R-R-R-R-Q-C-L-D-C-N-E-R-F-T-T-F-E-V-A-E-L-V-L-P-R-V-I-K-S-D-E-V-R-E-P-F-N-E-E-K-L-R-R-G-M-L-K-A-L-E-K-R-P-V-S-S-D-D-V-E-T-A-I-S-H-I-K-S-Q-L-R-A-T-G-E-R-E-V-P-T-K-M-V-G-N-L-V-M-E-A-L-K-R-L-D-K-V-A-Y-I-R-F-A-S-V-Y-R-S-F-E-D-V-R-E-F-G-E-E-I-A-R-L-Q-D"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-P-A-A-R-R-R-A-R-E-C-A-V-Q-A-L-Y-S-W-Q-L-S-K-N-D-I-A-D-V-E-L-Q-F-L-S-E-Q-D-V-K-D-V-D-I-A-Y-F-R-E-L-L-S-G-V-A-V-N-A-A-S-L-D-A-L-M-A-P-F-L-S-R-Q-L-E-E-L-G-Q-V-E-R-A-V-L-R-I-A-L-F-E-L-S-K-R-D-D-V-P-Y-K-V-A-I-N-E-A-I-E-L-A-K-T-F-G-A-E-D-S-H-K-F-V-N-G-V-L-D-K-V-A-P-T-V-R-K-R-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-P-K-K-A-A-S-P-E-I-K-A-A-S-F-E-T-S-L-S-E-L-E-Q-I-V-T-R-L-E-S-G-E-L-P-L-E-D-A-L-N-E-F-E-R-G-V-Q-L-A-R-Q-G-Q-Q-T-L-L-Q-A-E-Q-R-V-Q-I-L-L-S-D-D-V-D-A-P-L-K-P-F-T-P-D-T-E"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-G-G-I-G-N-L-M-K-Q-A-Q-Q-M-Q-E-K-M-Q-Q-M-Q-E-E-V-A-K-L-E-V-T-G-E-S-G-A-G-L-V-K-V-T-I-N-G-A-H-N-C-R-R-V-E-I-D-P-S-L-L-V-E-D-D-K-E-M-L-E-D-L-I-A-A-A-L-N-D-A-A-R-R-I-D-E-T-Q-K-E-K-M-A-S-V-S-N-G-M-Q-L-P-P-G-F-K-M-P-F"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-L-G-L-G-T-D-I-V-E-I-S-R-I-Q-A-V-V-E-R-T-G-E-R-L-A-R-R-I-L-S-P-S-E-W-Q-H-Y-Q-Q-H-Q-Q-P-V-R-F-L-A-K-R-F-A-V-K-E-A-A-A-K-A-F-G-T-G-I-R-N-G-L-A-F-N-Q-F-E-V-V-N-D-A-L-G-K-P-T-L-R-L-H-S-R-A-A-E-L-A-V-E-L-G-V-K-S-L-H-V-T-L-A-D-E-R-R-Y-A-C-A-T-V-I-I-E-S"} +{"text": "### FUNCTION Is able to transfer iron-sulfur clusters to apo-ferredoxin Multiple cycles of cluster formation and transfer are observed, suggesting that IscA acts catalytically Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB ### SEQUENCE -M-S-I-S-I-S-D-S-A-A-Q-R-V-S-A-F-L-N-H-R-G-K-G-L-G-L-R-L-G-V-R-T-S-G-C-S-G-M-A-Y-V-L-E-F-V-D-E-I-N-D-D-D-I-V-F-E-D-K-G-V-K-V-I-I-D-G-K-S-M-V-Y-L-D-G-T-E-L-D-F-V-K-E-G-L-N-E-G-F-K-F-N-N-P-N-V-S-N-E-C-G-C-G-E-S-F-N-V"} +{"text": "### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-T-G-I-Q-I-T-K-A-N-N-E-A-L-L-N-S-F-W-L-L-D-D-E-K-A-E-L-R-C-V-C-A-K-S-G-Y-A-E-D-Q-I-V-P-T-S-E-L-G-E-I-E-Y-R-E-V-P-L-E-V-Q-P-T-V-R-V-E-G-G-Q-H-L-N-V-N-V-L-S-R-D-T-L-E-D-A-V-K-N-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-T-R-T-F-T-E-S-L"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-T-A-I-D-V-M-W-V-G-L-G-G-G-I-G-S-L-L-R-W-W-I-G-L-S-I-G-K-V-Y-K-G-N-F-P-L-G-T-F-L-I-N-I-S-G-A-F-V-I-G-Y-L-S-I-L-F-S-V-D-W-R-D-R-Y-G-D-L-M-N-T-A-V-L-T-G-I-L-G-G-Y-T-T-F-S-S-M-Q-L-D-A-A-K-L-A-T-A-R-G-R-A-I-A-A-G-Y-L-I-I-S-V-L-V-G-L-A-A-A-A-F-G-A-W-L-A-Y"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-P-N-L-I-I-L-V-F-V-G-G-A-F-G-A-M-C-R-E-F-I-M-L-S-V-P-R-L-A-D-G-F-P-M-D-I-F-V-A-N-I-I-A-A-F-L-L-G-L-T-T-S-F-F-K-K-D-K-I-N-Q-Y-V-H-L-M-V-G-T-G-I-M-G-G-L-S-T-F-S-S-F-V-F-G-A-V-E-M-M-K-N-P-T-E-V-L-V-S-I-C-Y-L-V-A-S-L-I-V-G-F-I-A-V-E-L-G-L-M-I-G-P-K-E-K-P-K-D-P-Q-V-A-S-E"} +{"text": "### FUNCTION Required for growth and/or survival at acidic conditions ### SEQUENCE -M-K-K-V-L-A-L-M-V-A-A-T-L-G-L-S-S-V-A-F-A-A-D-T-T-A-T-A-T-P-A-A-T-S-T-T-A-T-V-A-A-Q-T-K-A-T-Q-H-Q-K-H-K-V-T-K-K-T-T-E-Q-K-A-Q-A-A-K-K-H-E-K-K-A-S-V-Q-K-T-P-V-Q-K-A-Q-A-A-K-K-H-V-K-K-A-S-V-Q-K-A-P-V-Q-K-A-Q-A-A-K-K-H-H-K-T-A-K-K-P-V-A-A-P-A-A"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-N-P-L-V-Y-F-S-S-S-S-E-N-S-H-R-F-V-E-K-L-Q-L-P-A-I-R-I-P-I-A-G-A-R-E-K-L-R-V-E-Q-P-Y-I-L-L-V-P-S-Y-G-G-G-S-P-V-G-A-V-P-I-Q-V-I-R-F-L-N-D-V-H-N-R-S-L-I-R-G-V-I-A-A-G-N-T-N-F-G-D-A-Y-C-L-A-G-D-I-I-S-H-K-C-Q-V-P-Y-L-Y-R-F-E-L-L-G-T-A-E-D-V-A-N-V-R-K-G-V-T-E-F-W-Q-R-Q-N"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-Q-V-I-L-D-L-Q-I-A-C-A-D-S-Q-G-L-P-T-E-G-D-F-Q-R-W-L-E-A-V-L-P-L-F-Q-P-V-S-E-V-T-I-R-L-V-D-E-A-E-S-H-D-L-N-L-T-Y-R-G-K-D-K-S-T-N-V-L-S-F-P-F-E-A-P-P-E-I-E-L-P-L-L-G-D-L-I-I-C-R-Q-V-V-E-K-E-A-I-E-Q-E-K-A-L-L-A-H-W-A-H-M-V-V-H-G-S-L-H-L-L-G-Y-D-H-I-D-D-E-E-A-E-E-M-E-L-I-E-T-E-I-M-H-G-L-G-Y-P-D-P-Y-I-S-E-K-D-P-D"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-L-Q-L-V-A-V-G-T-K-M-P-D-W-V-Q-T-G-F-I-E-Y-L-R-R-F-P-K-D-M-P-F-E-L-A-E-I-P-A-G-K-R-G-K-N-A-D-I-K-R-I-L-E-K-E-G-E-L-M-L-A-A-V-G-K-N-N-R-I-V-T-L-D-I-P-G-T-P-W-E-T-P-Q-L-A-Q-Q-L-E-R-W-K-Q-D-G-R-D-V-S-L-L-I-G-G-P-E-G-L-A-P-A-C-K-A-A-A-E-Q-S-W-S-L-S-P-L-T-L-P-H-P-L-V-R-V-L-V-A-E-S-L-Y-R-A-W-S-I-T-T-N-H-P-Y-H-R-E"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatE shares overlapping functions with TatA ### SEQUENCE -M-E-G-L-S-I-T-K-L-L-V-V-G-I-L-I-V-L-L-F-G-T-S-K-L-R-T-L-G-A-D-L-G-A-A-L-K-G-F-K-K-A-M-R-N-D-D-E-V-S-T-S-V-L-G-E-T-K-M-S-A-E-T-K-T-V-A-E-T-K-A-A-S-D-S-Q-A-A-A-S-V-E-R-K-D"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-F-N-T-L-L-A-V-F-I-G-G-G-V-G-S-M-A-R-W-L-V-S-L-K-L-N-S-A-S-A-H-L-P-V-G-T-L-I-V-N-L-V-G-A-F-I-I-G-L-T-L-A-F-F-S-R-M-T-H-I-D-P-V-W-K-L-L-I-T-T-G-F-C-G-G-L-T-T-F-S-T-F-S-V-E-V-V-Y-L-I-Q-E-G-K-L-A-W-A-A-G-T-I-L-L-N-V-A-G-S-L-A-M-T-M-L-A-F-I-L-V-N-N-F-A-S-Q"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-G-G-K-R-V-Q-P-A-R-P-N-R-I-N-K-E-I-R-A-T-E-V-R-L-T-G-V-D-G-E-Q-I-G-I-V-S-L-N-E-A-L-E-K-A-E-E-A-G-V-D-L-V-E-I-S-P-N-A-E-P-P-V-C-R-I-M-D-Y-G-K-F-L-Y-E-K-S-K-S-T-K-E-Q-K-K-K-Q-K-V-I-Q-V-K-E-I-K-F-R-P-G-T-D-D-G-D-Y-Q-V-K-L-R-N-L-I-R-F-L-E-D-G-D-K-A-K-I-T-L-R-F-R-G-R-E-M-A-H-Q-Q-I-G-M-E-V-L-N-R-V-R-K-D-L-C-E-D-S-D-L-A-V-V-E-S-F-P-T-R-I-E-G-R-Q-M-I-M-V-L-A-P-K-K-R-Q"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-A-R-H-K-K-I-L-K-Q-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-A-R-Q-N-G-L-S-Y-S-R-F-I-N-G-L-K-K-A-S-V-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-V-A-F-S-A-L-V-E-K-A-K-A-A-L-A"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-E-M-S-E-H-L-F-E-K-L-G-L-S-K-R-D-A-K-D-L-V-E-L-F-F-E-E-V-R-R-A-L-E-N-G-E-Q-V-K-L-S-G-F-G-N-F-D-L-R-D-K-N-Q-R-P-G-R-N-P-K-T-G-E-D-I-P-I-T-A-R-R-V-V-T-F-R-P-G-Q-K-L-K-S-R-V-E-S-A-T-P-K-E"} +{"text": "### FUNCTION Required for growth and/or survival at acidic conditions ### SEQUENCE -M-K-T-V-L-T-L-I-V-A-A-T-L-S-L-F-S-V-A-F-A-A-D-T-V-V-P-Q-T-T-P-T-A-T-A-P-A-P-A-V-H-N-A-S-A-K-T-M-H-H-K-K-A-Q-K-P-N-T-I-K-N-T-H-K-T-A-P-E-Q-K-A-Q-A-A-Q-K-H-H-K-A-A-H-S-H-K-A-P-T-V-A-P-A-A-K"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-T-E-Y-L-L-L-F-V-G-T-V-L-V-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-L-E-T-A-I-G-M-G-L-A-T-T-F-V-L-T-L-A-S-V-C-A-W-M-V-N-S-F-I-L-L-P-L-G-L-I-Y-L-R-T-L-A-F-I-L-V-I-A-V-V-V-Q-F-T-E-L-V-V-R-K-T-S-P-T-L-Y-R-L-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-V-N-Q-S-H-N-F-M-Q-S-A-V-Y-G-F-S-A-A-A-G-F-S-L-V-M-V-L-F-A-A-I-R-E-R-L-A-V-A-D-V-P-A-P-F-R-G-S-S-I-A-L-I-T-A-G-L-M-S-L-A-F-M-G-F-T-G-L-V-K-F"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-Q-L-L-D-F-L-P-L-V-V-F-F-I-F-Y-K-M-Y-D-I-F-V-A-S-G-A-L-I-V-A-T-L-V-A-L-A-F-T-W-L-K-Y-R-K-V-E-K-M-T-L-V-T-A-A-M-V-L-V-F-G-T-L-T-L-A-F-H-S-D-L-F-I-K-W-K-V-T-V-L-Y-V-L-F-A-L-A-L-L-V-S-Q-W-V-M-K-K-P-L-I-Q-R-M-L-G-K-E-L-T-L-P-D-K-V-W-S-T-L-N-L-S-W-A-I-F-F-L-V-C-G-L-L-N-I-Y-V-A-F-W-L-P-Q-D-I-W-V-N-F-K-V-F-G-L-T-A-L-T-L-I-F-T-L-I-S-G-V-Y-I-Y-R-H-M-P-E-E-Q-K-K-S"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-L-Q-F-L-N-R-C-S-R-G-R-G-A-W-L-L-M-A-L-T-A-F-L-L-E-L-T-A-L-Y-F-Q-H-I-M-L-L-Q-P-C-V-M-C-I-Y-E-R-V-A-L-F-G-I-L-G-A-S-L-L-G-A-I-A-P-R-S-P-L-R-Y-L-A-I-A-V-W-I-Y-S-A-W-K-G-V-Q-L-A-W-A-H-T-M-L-Q-L-N-P-S-P-F-N-T-C-D-F-F-V-N-F-P-S-W-L-P-L-D-K-W-L-P-A-V-F-A-A-S-G-D-C-S-E-R-Q-W-Q-F-M-S-L-E-M-P-Q-W-L-V-G-I-F-A-A-Y-L-V-I-A-V-L-V-L-I-S-Q-F-V-K-P-K-R-R-D-L-F-G-R"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-A-L-L-D-F-F-L-S-R-K-K-P-T-A-N-I-A-K-E-R-L-Q-I-I-V-A-E-R-R-R-G-D-S-E-P-H-Y-L-P-D-L-K-R-D-I-L-A-V-I-C-K-Y-I-Q-I-D-P-E-M-L-H-V-Q-F-E-Q-K-G-D-D-I-S-V-L-E-L-N-V-T-L-P-E-T-E-E-T-P-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-S-I-K-L-I-V-G-L-A-N-P-G-A-E-Y-A-Q-T-R-H-N-A-G-A-W-Y-V-D-L-L-A-E-R-H-N-Q-S-L-K-E-E-S-K-F-F-G-Y-T-A-R-L-N-L-A-G-Q-D-I-R-L-L-V-P-A-T-F-M-N-L-S-G-K-A-V-A-A-M-A-S-F-Y-R-I-L-P-E-E-I-L-V-A-H-D-E-L-D-I-L-P-G-M-A-K-L-K-L-G-G-G-N-G-G-H-N-G-L-K-D-I-Q-N-K-L-G-N-N-P-N-F-Y-R-L-R-I-G-I-G-H-P-G-D-K-S-K-V-T-G-F-V-L-G-K-P-P-A-S-E-Q-T-L-I-D-D-A-I-D-E-S-I-R-C-T-E-V-L-L-N-E-G-M-T-K-A-M-N-R-L-H-A-F-K-A-S-A"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-N-L-S-A-T-I-I-L-A-F-A-M-S-M-D-A-F-A-A-S-I-G-K-G-A-T-L-Y-K-P-R-F-R-E-A-L-R-T-G-L-I-F-G-V-I-E-A-I-T-P-L-I-G-W-C-I-G-L-F-A-S-Q-Y-I-M-E-W-D-H-W-I-A-F-S-L-L-F-I-L-G-C-R-M-I-F-E-G-M-K-Q-R-V-A-E-T-E-K-M-R-S-H-S-F-W-V-L-V-T-T-A-I-A-T-S-L-D-A-M-A-I-G-V-G-L-A-F-L-Q-V-D-I-V-H-T-A-M-A-I-G-L-A-T-M-I-M-A-T-L-G-M-L-I-G-R-Y-I-G-P-L-L-G-K-R-A-E-I-I-G-G-I-V-L-I-G-I-G-F-N-I-L-Y-E-H-M-H-L-T-A"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-T-I-E-E-R-V-K-K-I-I-V-E-Q-L-G-V-K-E-D-E-V-K-N-S-A-S-F-V-E-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-A-A-I-D-F-I-N-A-N-Q-Q"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine ### SEQUENCE -M-L-E-F-E-G-R-I-I-D-T-D-A-Q-G-Y-L-K-N-S-T-D-W-S-E-A-L-A-P-V-L-A-E-Q-E-G-I-T-L-T-E-P-H-W-E-V-V-R-F-V-R-A-F-Y-Q-E-F-N-T-S-P-A-I-R-M-L-V-K-A-M-A-Q-K-Y-G-E-E-K-G-N-S-R-Y-L-Y-R-L-F-P-K-G-P-A-K-Q-A-T-K-I-A-G-L-P-K-P-V-K-C-I"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-E-L-T-T-R-T-I-A-A-R-K-H-I-A-L-V-S-H-D-H-C-K-K-S-L-L-A-W-V-M-E-N-R-D-L-L-A-Q-H-E-L-Y-A-T-G-T-T-G-N-L-V-Q-K-A-T-G-I-D-V-H-C-L-L-S-G-P-M-G-G-D-Q-E-V-G-A-L-I-S-E-K-K-I-D-I-L-I-F-F-W-D-P-L-N-A-V-P-H-D-P-D-V-K-A-L-L-R-L-A-T-V-W-N-I-P-V-A-T-N-R-S-T-A-D-F-L-I-G-S-T-L-F-S-S-E-V-T-I-A-I-P-D-Y-D-R-Y-M-Q-Q-R-L-D-L-K"} +{"text": "### FUNCTION Required for spatial organization of the terminus region of the chromosome during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-Q-L-E-N-L-E-S-G-W-K-W-A-Y-L-V-K-K-H-R-E-G-E-A-I-T-R-H-I-E-N-S-A-A-Q-D-A-V-E-Q-L-M-K-L-E-N-E-P-V-K-V-Q-E-W-I-D-A-H-M-N-V-N-L-A-T-R-M-K-Q-T-I-R-A-R-R-K-R-H-F-N-A-E-H-Q-H-T-R-K-K-S-I-D-L-E-F-L-V-W-Q-R-L-A-V-L-A-R-R-R-G-N-T-L-S-D-T-V-V-Q-L-I-E-D-A-E-R-K-E-K-Y-A-S-Q-M-S-S-L-K-Q-D-L-K-D-I-L-D-K-E-V"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-R-L-A-G-Q-Q-S-H-V-P-A-K-V-V-E-D-A-V-K-E-M-L-E-H-M-A-G-T-L-A-E-G-E-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-A-P-R-V-G-R-N-P-K-T-G-D-K-V-E-L-E-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-D-R-A-N-I-Y-G"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-G-K-N-N-D-W-L-N-F-E-H-L-V-K-D-K-Q-I-E-A-L-Q-P-P-S-M-Y-K-V-I-L-N-N-D-D-Y-T-P-M-E-F-V-I-D-V-L-Q-K-F-F-S-Y-D-I-E-R-A-T-Q-L-M-L-N-V-H-Y-Q-G-K-A-I-C-G-V-F-T-A-E-V-A-E-T-K-V-A-H-V-N-Q-Y-A-R-E-N-E-H-P-L-L-C-T-L-E-K-A"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-T-T-I-N-V-E-V-R-N-D-Q-G-K-G-A-S-R-R-L-R-A-A-N-K-F-P-A-I-V-Y-G-G-S-E-A-A-I-S-I-A-L-D-H-D-T-T-K-N-L-E-L-K-P-G-F-Y-D-S-V-L-T-L-V-I-D-G-K-E-T-K-V-K-V-Q-A-V-Q-R-H-A-F-K-P-K-L-T-H-I-D-F-V-R-V"} +{"text": "### FUNCTION General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases ### SEQUENCE -M-K-K-C-S-I-I-L-A-S-V-L-L-A-T-S-I-N-A-I-A-D-T-P-T-P-L-N-Q-Q-Q-P-L-E-K-I-A-P-Y-P-Q-A-E-K-G-M-S-R-Q-V-I-F-L-E-P-Q-K-D-E-S-R-F-K-V-E-L-L-I-G-K-T-L-N-V-D-C-N-R-H-M-L-G-G-N-L-E-T-R-T-L-S-G-W-G-F-D-Y-L-V-M-D-K-I-S-Q-P-A-S-T-M-M-A-C-P-E-D-S-K-P-Q-V-K-F-V-T-A-N-L-G-D-A-A-M-Q-R-Y-N-S-R-L-P-I-V-V-Y-V-P-Q-G-V-E-V-K-Y-R-I-W-E-A-G-E-D-I-R-S-A-Q-V-K"} +{"text": "### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-V-G-M-Q-P-I-R-R-Q-Q-L-I-E-A-T-M-A-A-V-N-E-V-G-M-H-E-A-S-I-A-Q-I-A-K-R-A-G-V-S-N-G-I-I-S-H-Y-F-R-D-K-N-G-L-L-E-A-T-M-R-Y-L-I-R-H-L-G-E-A-V-K-Q-H-L-A-A-L-S-V-N-D-P-R-A-R-L-R-A-I-A-E-G-N-F-D-D-S-Q-I-N-S-A-A-M-K-T-W-L-A-F-W-A-S-S-M-H-S-P-Q-L-Y-R-L-Q-Q-V-N-N-R-R-L-Y-S-N-L-C-A-E-F-K-R-C-L-P-R-E-Q-A-Q-L-A-A-K-G-M-A-G-L-I-D-G-L-W-L-R-S-A-L-S-G-E-H-F-N-R-Q-E-A-L-L-I-I-H-N-Y-I-E-Q-Q-L-N-I-K-Y-K-C"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-T-K-K-K-A-Y-K-P-G-S-A-T-I-A-Q-N-K-R-A-R-H-E-Y-F-I-E-E-E-F-E-A-G-L-A-L-Q-G-W-E-V-K-S-L-R-A-G-K-A-N-I-S-D-S-Y-V-M-F-K-N-G-E-A-F-L-F-G-A-T-I-T-P-L-N-V-A-S-T-H-V-V-C-E-P-M-R-T-R-K-L-L-L-N-K-R-E-L-D-S-L-F-G-R-V-N-R-E-G-Y-T-V-V-A-L-S-M-Y-W-K-N-A-W-V-K-V-K-I-G-V-A-K-G-K-K-D-N-D-K-R-D-D-I-R-D-R-E-W-K-L-D-K-A-R-I-M-K-H-A-N-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-E-I-R-K-D-A-E-V-R-M-E-K-C-L-E-A-F-Q-N-H-I-S-K-I-R-T-G-R-A-S-P-S-I-L-D-G-I-Q-V-E-Y-Y-G-T-A-T-P-L-R-Q-L-A-N-I-V-V-E-D-S-R-T-L-A-L-T-V-F-D-R-S-L-S-A-A-V-E-K-A-I-M-T-S-D-L-G-L-N-P-S-S-A-G-T-V-I-R-V-P-L-P-A-L-T-E-E-R-R-K-D-L-I-K-V-V-R-A-E-A-E-Q-G-R-V-S-I-R-N-V-R-R-D-A-N-D-K-V-K-A-L-L-K-D-K-E-I-S-E-D-E-D-R-R-S-Q-D-D-V-Q-K-L-T-D-A-Y-I-K-K-V-D-A-A-L-A-V-K-E-A-E-L-M-D-F"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-K-K-D-A-E-R-Q-D-F-Q-L-Y-P-G-E-I-G-K-R-I-Y-N-E-I-S-K-E-A-W-S-Q-W-I-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-I-E-D-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-Q-D-V-H-I-A-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-N-R-T-I-I-A-F-D-F-G-T-K-S-I-G-V-A-I-G-Q-E-V-T-G-T-A-R-A-L-T-A-F-K-A-Q-D-G-T-P-D-W-Q-Q-V-E-K-L-L-K-E-W-Q-P-N-L-V-V-V-G-L-P-L-N-M-D-G-T-E-Q-P-L-T-A-R-A-R-R-F-A-N-R-L-H-G-R-F-G-V-Q-V-A-L-Q-D-E-R-L-S-T-V-E-A-R-A-N-L-F-D-R-G-G-Y-R-A-L-D-K-G-S-V-D-A-A-S-A-V-I-I-L-E-S-W-F-D-E-Q-A-G"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-V-P-T-E-L-K-Y-A-L-S-H-E-W-V-R-A-D-G-D-G-V-Y-S-V-G-I-T-E-H-A-Q-E-L-L-G-D-M-V-F-V-D-L-P-E-V-G-S-D-V-S-A-G-S-D-C-A-V-A-E-S-V-K-A-A-S-D-I-Y-A-P-I-S-G-E-I-V-A-V-N-T-E-L-E-N-S-P-E-L-V-N-S-A-P-Y-T-D-G-W-L-F-S-I-K-A-A-D-E-S-E-L-D-N-L-L-D-A-D-A-Y-L-A-A-I-E-E"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-E-I-D-N-K-A-R-I-H-W-A-C-R-R-G-M-R-E-L-D-I-S-I-M-P-F-F-E-Y-E-Y-D-S-L-S-D-N-E-K-Q-A-F-I-R-L-L-E-C-D-D-P-D-L-F-N-W-L-M-N-H-G-E-P-Q-D-S-E-L-Y-Q-M-V-K-L-I-Q-S-R-N-K-A-R-G-P-V-A-M"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-D-D-G-Y-R-P-N-V-G-I-V-I-C-N-R-Q-G-E-V-L-W-A-R-R-Y-G-Q-H-S-W-Q-F-P-Q-G-G-I-N-P-G-E-T-P-E-Q-A-M-Y-R-E-L-F-E-E-V-G-L-N-K-K-D-V-R-I-L-A-S-T-R-N-W-L-R-Y-K-L-P-K-R-L-V-R-W-D-T-K-P-V-C-I-G-Q-K-Q-R-W-F-L-L-Q-L-M-C-N-E-A-E-I-N-M-Q-R-S-S-T-P-E-F-D-G-W-R-W-V-S-Y-W-Y-P-V-R-Q-V-V-S-F-K-R-D-V-Y-R-R-V-M-K-E-F-A-A-T-V-M-P-V-Q-E-V-A-P-P-R-V-P-P-A-Y-R-R-K-R-G"} +{"text": "### FUNCTION Regulates secA expression by translational coupling of the secM secA operon Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation ### SEQUENCE -M-I-G-I-L-N-R-W-R-Q-F-G-R-R-Y-F-W-P-H-L-L-L-G-M-V-A-A-S-L-G-V-P-L-N-L-S-G-V-P-D-H-A-A-L-A-N-T-S-S-S-Q-S-R-Q-N-H-G-T-T-N-F-N-S-L-A-L-L-H-D-I-H-R-R-L-S-F-S-V-D-Y-W-Q-Q-H-A-L-R-T-V-I-R-H-L-S-F-A-L-A-P-Q-A-A-Y-A-R-V-Q-E-V-A-E-T-E-R-V-A-P-S-K-I-Q-Q-L-A-L-L-D-T-L-N-A-L-L-T-H-E-F-K-P-P-A-I-I-R-Y-T-E-Q-V-E-R-P-V-L-S-P-Y-K-P-G-L-W-L-A-Q-V-Q-G-I-R-A-G-P-A-N-L-S"} +{"text": "### FUNCTION Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall gene cluster Acts by binding directly to DNA May also regulate the expression of genes outside the dcw cluster ### SEQUENCE -M-F-R-G-A-T-M-V-N-L-D-S-K-G-R-L-A-V-P-T-R-Y-R-E-S-L-N-E-E-S-Q-G-Q-M-V-C-T-I-D-L-H-Q-P-C-L-L-L-Y-P-L-P-E-W-E-I-I-E-Q-K-L-S-R-L-S-S-M-N-P-A-E-R-R-V-Q-R-L-L-L-G-H-A-S-E-C-Q-M-D-G-A-G-R-L-L-I-A-G-T-L-R-Q-H-A-G-L-N-K-E-V-M-L-V-G-Q-F-N-K-F-E-L-W-D-E-Q-T-W-Y-Q-Q-V-K-D-D-I-D-A-E-Q-S-T-Q-E-P-L-S-E-R-L-Q-G-L-S-L"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-A-K-F-I-Q-H-I-G-L-V-A-P-L-D-A-A-N-V-D-T-D-A-I-I-P-K-Q-F-L-Q-K-V-T-R-T-G-F-G-Q-H-L-F-N-D-W-R-F-L-D-D-A-G-K-V-P-N-P-D-F-V-L-N-L-P-R-Y-Q-G-A-T-I-L-L-A-R-E-N-F-G-C-G-S-S-R-E-H-A-P-W-A-L-T-D-F-G-F-K-V-V-I-A-P-S-F-A-D-I-F-Y-G-N-A-F-N-N-Q-L-L-P-V-T-L-S-E-A-D-I-D-T-L-F-Q-L-V-K-E-N-E-G-I-E-F-V-V-D-L-E-Q-Q-T-V-N-A-G-G-K-S-Y-A-F-E-I-D-P-F-R-R-H-C-M-I-N-G-L-D-S-I-G-L-T-L-Q-H-E-H-N-I-S-A-Y-E-K-Q-Q-P-E-F-L-R"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-R-A-V-Q-S-E-K-R-R-K-H-N-A-S-R-R-S-M-V-R-T-F-I-K-K-V-Y-A-A-I-A-A-G-D-K-D-A-A-Q-K-A-F-N-E-M-Q-P-I-V-D-R-Q-S-C-K-G-L-I-H-K-N-K-A-A-R-H-K-S-N-L-V-A-Q-I-N-A-M-Q"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-E-N-Q-N-N-L-I-W-I-D-L-E-M-T-G-L-D-P-E-R-D-R-I-I-E-I-A-T-L-V-T-D-A-N-L-N-I-L-A-E-G-P-V-L-A-V-H-Q-S-A-E-Q-L-G-L-M-D-E-W-N-V-R-T-H-T-G-S-G-L-V-E-R-V-K-A-S-P-F-N-D-R-D-A-E-L-Q-T-I-E-F-L-K-Q-W-V-P-A-G-V-S-P-I-C-G-N-S-V-G-Q-D-R-R-F-L-F-R-Y-M-P-E-L-E-A-Y-F-H-Y-R-Y-V-D-V-S-T-L-K-E-L-A-R-R-W-K-P-E-I-L-A-G-F-K-K-Q-N-T-H-Q-A-L-D-D-I-R-E-S-V-A-E-L-A-Y-Y-R-E-H-F-I-Q-S"} +{"text": "### FUNCTION Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion ### SEQUENCE -M-T-T-K-R-K-A-Y-V-R-T-M-A-P-N-W-W-Q-Q-L-G-F-Y-R-F-Y-M-L-R-E-G-T-S-I-P-A-V-W-F-S-V-L-L-I-Y-G-V-F-A-L-K-S-G-P-A-G-W-E-G-F-V-S-F-L-Q-N-P-L-V-L-F-L-N-I-L-T-L-F-A-A-L-L-H-T-K-T-W-F-E-L-A-P-K-A-V-N-I-I-V-K-S-E-K-M-G-P-E-P-M-I-K-A-L-W-V-V-T-V-V-A-S-A-I-I-L-A-V-A-L-L"} +{"text": "### FUNCTION Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion ### SEQUENCE -M-N-Q-V-P-K-R-S-D-E-P-I-F-W-G-L-F-G-A-G-G-M-W-G-A-I-I-A-P-V-I-I-L-L-V-A-I-L-L-P-L-G-A-F-P-G-D-A-L-S-Y-E-R-I-L-A-F-C-Q-S-F-I-G-R-V-F-L-L-L-M-I-I-L-P-L-W-C-G-L-H-R-I-H-H-A-M-H-D-L-K-I-H-V-P-A-G-K-W-V-F-Y-G-L-A-A-I-L-S-V-V-T-F-I-G-V-L-T-L"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-S-Y-Y-S-N-D-F-R-P-G-L-K-I-M-F-E-G-E-P-Y-A-V-E-S-S-E-F-V-K-P-G-K-G-Q-A-F-A-R-V-K-M-R-R-L-L-T-G-G-R-V-E-K-T-F-K-S-T-D-S-L-E-G-A-D-V-N-D-M-N-L-T-Y-L-Y-N-D-G-E-F-W-H-F-M-N-N-E-T-Y-E-Q-L-Q-A-D-A-K-A-V-G-D-N-G-K-W-L-I-D-Q-A-E-C-I-V-T-L-W-N-G-Q-P-I-A-V-T-P-P-N-F-V-E-L-E-I-V-D-T-D-P-G-L-K-G-D-T-A-G-T-G-G-K-P-A-T-L-S-T-G-A-V-V-K-V-P-L-F-V-Q-V-G-E-I-I-K-V-D-T-R-S-G-E-Y-V-S-R-V-K"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-F-M-K-E-F-R-E-F-A-M-R-G-N-V-V-D-L-A-V-G-V-I-I-G-A-A-F-G-R-I-V-S-S-L-V-A-D-I-I-M-P-P-L-G-L-L-L-G-G-V-D-F-K-Q-F-H-F-V-L-R-A-A-E-G-T-I-P-A-V-V-M-N-Y-G-T-F-I-Q-S-I-F-D-F-V-I-V-A-L-A-I-F-S-A-V-K-L-M-N-K-L-R-R-E-K-A-E-E-E-P-A-T-P-P-A-P-T-T-E-E-I-L-L-A-E-I-R-D-L-L-K-A-Q-H-T-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-A-P-I-R-A-R-K-R-V-R-K-T-V-S-D-G-V-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-G-W-A-T-A-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-R-C-A-E-A-V-K-E-Y-G-I-K-N-L-E-V-M-V-K-G-P-G-P-G-R-E-S-T-I-R-A-L-N-A-A-G-F-R-I-T-N-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-T-V-I-A-L-T-A-I-F-G-I-G-K-T-R-S-Q-A-I-C-V-A-A-G-I-A-E-H-V-K-I-S-E-L-S-E-E-Q-I-E-K-L-R-D-E-V-A-K-Y-V-V-E-G-D-L-R-R-E-V-T-L-S-I-K-R-L-M-D-L-G-T-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-S-P-A-E-G-A-K-H-A-P-K-R-V-G-R-G-I-G-S-G-L-G-K-T-A-G-R-G-H-K-G-Q-N-S-R-S-G-G-G-V-R-R-G-F-E-G-G-Q-M-P-L-Y-R-R-L-P-K-F-G-F-T-S-R-K-A-M-I-T-A-E-V-R-L-S-E-L-A-L-V-E-G-D-V-I-D-L-N-T-L-K-A-A-N-V-V-G-I-Q-M-E-F-V-K-V-I-L-S-G-E-V-N-R-A-V-T-L-R-G-L-R-V-T-K-G-A-R-A-A-I-E-A-A-G-G-K-I-E-E"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-H-I-E-K-Q-A-G-E-L-Q-E-K-L-I-A-V-N-R-V-S-K-T-V-K-G-G-R-I-F-S-F-T-A-L-T-V-V-G-D-G-N-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-A-M-I-N-V-A-L-N-N-G-T-L-Q-H-P-V-K-G-A-H-T-G-S-R-V-F-M-Q-P-A-S-E-G-T-G-I-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-H-N-V-L-A-K-A-Y-G-S-T-N-P-I-N-V-V-R-A-T-I-A-A-L-E-D-M-K-S-P-E-M-V-A-A-K-R-G-K-S-V-E-E-I-L-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-A-A-R-I-R-R-A-T-R-A-R-R-K-L-K-E-L-G-A-T-R-L-V-V-H-R-T-P-R-H-I-Y-A-Q-V-I-A-P-N-G-S-E-I-L-V-A-A-S-T-V-E-K-A-I-N-E-Q-L-K-Y-A-G-N-K-D-A-A-A-A-V-G-K-T-I-A-E-R-A-L-E-K-G-I-T-K-V-S-F-D-R-S-G-F-Q-Y-H-G-R-V-Q-A-L-A-D-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-A-D-M-L-T-R-I-R-N-G-Q-A-A-N-K-V-A-V-T-M-P-S-S-K-L-K-V-A-I-A-N-V-L-K-E-E-G-F-I-E-D-F-K-I-E-G-D-T-K-P-V-L-E-L-A-L-K-Y-F-Q-G-K-A-V-V-E-S-I-Q-R-I-S-R-P-G-L-R-I-Y-K-K-K-D-E-L-P-K-V-M-A-G-L-G-I-A-V-I-S-T-S-K-G-V-M-T-D-R-A-A-R-Q-A-G-L-G-G-E-I-I-C-Y-V-A"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-E-V-V-R-V-K-L-A-N-K-Y-R-A-K-R-E-E-L-K-A-I-I-S-G-V-N-S-S-D-E-D-R-W-D-A-V-L-K-L-Q-S-L-P-R-D-S-S-P-S-R-Q-R-N-R-C-N-Q-T-G-R-P-H-G-F-L-R-K-F-G-L-S-R-I-K-V-R-E-T-A-M-R-G-E-I-P-G-L-K-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-K-D-E-V-V-K-Q-L-M-S-Q-F-G-Y-D-S-V-M-Q-V-P-R-V-E-K-I-T-L-N-M-G-V-G-E-A-I-A-D-K-K-L-L-D-N-A-A-A-D-L-A-A-I-S-G-Q-K-P-F-I-T-K-A-R-K-S-V-A-G-F-K-I-R-Q-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-E-F-F-E-R-L-I-T-I-A-V-P-R-I-R-D-F-R-G-L-S-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-Y-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-T-A-K-S-D-D-E-G-R-A-L-L-A-A-F-K-F-P-F-R-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-D-D-E-V-I-V-L-T-G-K-D-K-G-K-R-G-K-V-K-N-V-L-S-S-G-K-V-I-V-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-L-N-Q-P-G-G-I-V-E-K-E-A-A-I-Q-V-S-N-L-A-L-F-N-A-T-T-G-K-A-D-R-V-G-F-R-F-E-D-G-K-K-V-R-F-F-K-S-T-S-E-T-I-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-T-D-Q-I-R-T-L-Q-G-R-V-V-S-D-K-M-E-K-S-M-V-V-A-I-E-R-V-V-K-H-P-I-Y-G-K-F-I-R-R-T-T-K-L-H-V-H-D-E-N-N-E-C-G-I-G-D-V-V-E-I-R-E-C-R-P-L-S-K-T-K-S-W-T-L-V-R-V-V-E-K-A-I-L"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-M-H-K-G-R-N-R-G-L-A-Q-G-T-D-V-S-F-G-E-F-G-L-K-A-C-G-R-C-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-A-I-K-R-Q-G-K-V-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-V-L-F-E-M-A-G-V-P-E-E-T-A-R-E-A-F-K-L-A-A-A-K-L-P-V-G-T-T-F-V-T-K-T-V-M"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-I-A-K-H-R-H-A-R-S-S-A-Q-K-V-R-L-V-A-D-L-I-R-G-K-K-V-S-Q-A-L-E-T-L-T-Y-T-N-K-K-A-A-G-L-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-D-G-A-D-I-D-D-L-K-V-T-K-I-F-V-D-E-G-P-S-M-K-R-I-M-P-R-A-K-G-R-A-D-R-I-L-K-R-T-S-H-I-T-V-V-V-S-D-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-V-E-K-A-V-E-S-G-D-K-K-P-I-R-T-W-S-R-R-S-T-V-F-P-N-M-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-F-V-S-D-E-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-A-A-D-K-K-A-K-K-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-I-G-Q-R-K-I-L-P-D-P-K-F-G-S-E-L-L-A-K-F-V-N-I-L-M-V-D-G-K-K-S-T-A-E-A-I-V-Y-T-A-L-E-T-L-A-Q-R-S-G-K-D-F-L-E-A-F-E-V-A-L-D-N-V-R-P-T-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-P-V-R-R-N-A-L-A-M-R-W-I-V-D-A-A-R-K-R-G-D-K-S-M-A-L-R-L-A-N-E-L-S-D-A-A-E-N-K-G-S-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-N-Q-L-V-R-K-P-R-S-M-K-V-A-K-S-N-V-P-A-L-E-A-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-T-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-I-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-A-L-D-C-S-G-V-K-D-R-K-Q-S-R-S-K-Y-G-V-K-K-P-K-A"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-L-Y-T-V-S-H-S-P-Y-H-C-D-L-S-A-L-L-R-L-A-T-S-E-D-D-I-L-L-L-Q-D-G-V-I-A-A-L-K-E-S-E-T-L-K-L-L-L-N-N-P-A-S-L-F-V-L-E-D-D-V-I-A-R-G-L-V-G-Q-I-S-D-N-A-T-L-I-S-Y-T-H-F-V-D-L-T-L-R-H-Q-Q-Q-L-A-W"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-A-R-K-R-I-A-F-I-F-T-Q-G-P-H-G-S-S-A-G-R-E-G-L-D-A-L-L-A-T-S-A-L-S-E-D-I-G-V-F-F-I-S-D-G-V-L-Q-L-L-P-Q-Q-Q-P-E-K-I-L-A-R-N-Y-I-A-T-F-G-V-L-P-L-Y-D-V-E-N-C-Y-L-C-E-R-S-L-Q-Q-R-G-L-S-K-M-A-D-W-I-L-D-V-T-V-L-S-P-A-D-L-R-R-E-L-G-T-Y-D-V-V-L-T-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-S-A-L-K-Y-C-L-L-V-T-G-P-A-Y-G-T-Q-Q-A-S-S-A-Y-Q-F-A-Q-A-V-V-G-A-G-H-H-L-V-S-I-F-F-Y-R-E-G-V-L-N-A-N-Q-L-T-A-P-A-S-D-E-F-D-L-V-R-A-W-Q-Q-L-A-A-E-Q-A-V-T-L-N-V-C-V-A-A-A-L-R-R-G-I-T-D-Q-H-E-A-E-Q-L-N-L-A-A-A-N-L-Q-P-G-F-T-L-S-G-L-G-A-L-A-E-A-T-L-T-C-D-R-M-V-Q-F"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-A-K-S-N-Y-I-T-R-E-G-W-Q-A-L-D-R-E-L-H-Y-L-W-R-E-E-R-P-V-V-T-Q-A-V-S-E-A-A-A-M-G-D-R-S-E-N-A-E-Y-I-Y-G-K-K-R-L-R-E-I-D-R-R-V-R-F-L-A-K-R-L-E-V-L-K-I-V-D-P-D-P-R-Q-E-G-K-V-F-F-G-A-W-V-R-V-E-N-E-Q-E-E-Q-R-I-F-R-L-V-G-P-D-E-F-D-P-A-K-K-W-I-S-I-D-S-P-V-A-R-A-L-I-G-K-Q-V-D-D-E-V-T-V-Q-T-P-N-G-E-A-T-Y-W-I-L-E-I-R-Y-R-P-F-D-E-D-R-P-F-N-E-D-I-D-N"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-T-I-T-D-A-A-Q-S-H-F-A-K-L-L-A-N-Q-E-E-G-T-Q-I-R-V-F-V-I-N-P-G-T-P-T-A-E-C-G-V-S-Y-C-P-P-D-A-V-E-A-T-D-T-E-L-K-F-E-Q-L-S-A-Y-V-D-E-L-S-V-P-Y-L-Q-D-A-E-I-D-F-V-T-D-Q-L-G-S-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-D-D-S-A-P-L-M-E-R-V-E-Y-V-L-Q-S-Q-I-N-P-Q-L-A-G-H-G-G-R-V-T-L-M-E-I-T-P-E-G-L-A-I-L-Q-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-E-G-I-E-K-E-L-L-Q-K-F-P-E-L-K-G-V-R-D-L-T-E-H-Q-R-G-E-H-S-Y-Y"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-E-Q-F-E-A-T-S-V-E-Q-A-Y-L-R-W-K-E-G-K-T-A-L-V-D-I-R-D-P-Q-S-Y-E-A-G-H-A-P-G-A-F-H-L-T-N-S-S-L-H-T-F-M-Q-Q-T-D-F-D-Q-P-V-M-V-M-C-Y-H-G-N-S-S-K-G-A-A-Q-Y-L-L-Q-Q-G-F-D-V-V-Y-S-I-D-G-G-F-E-A-W-A-R-S-Y-P-Q-D-I-T-S-E-S-R"} +{"text": "### FUNCTION This regulatory protein, when combined with SAM represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-A-E-W-N-G-E-Y-V-S-P-Y-A-E-H-G-K-K-S-K-Q-V-K-K-I-T-V-S-I-P-L-K-V-L-K-I-L-T-D-E-R-T-R-R-Q-V-N-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-F-T-G-Q-P-L-P-N-D-E-D-L-R-K-E-R-S-D-E-I-P-E-A-A-K-I-L-M-R-E-L-G-V-D-P-D-T-W-E-Y"} +{"text": "### FUNCTION Globally modulates RNA abundance by binding to RNase E and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome Modulates RNA-binding and helicase activities of the degradosome ### SEQUENCE -M-K-Y-D-T-S-D-L-C-D-I-Y-H-E-E-V-N-V-V-E-P-L-F-S-N-F-G-G-R-T-S-F-G-G-K-I-T-T-V-K-C-F-E-D-N-G-L-L-F-D-L-L-E-E-N-G-L-G-R-V-L-V-V-D-G-G-G-S-V-R-R-A-L-I-N-A-E-L-A-E-L-A-L-K-N-E-W-E-G-I-V-V-Y-G-A-V-R-Q-V-D-D-L-A-E-L-D-I-G-I-Q-A-M-A-A-I-P-V-G-A-A-D-E-G-V-G-E-S-D-I-R-V-N-F-G-G-V-T-F-F-S-G-D-H-L-Y-A-D-N-T-G-I-I-L-S-E-D-P-L-D-I-E"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-E-Q-N-N-T-E-M-A-F-Q-I-Q-R-I-Y-T-K-D-I-S-F-E-A-P-N-A-P-Q-V-F-Q-Q-D-W-Q-P-E-V-K-L-D-L-D-T-A-S-S-Q-L-A-E-D-V-Y-E-V-V-L-R-V-T-V-T-A-S-L-G-E-E-T-A-F-L-C-E-V-Q-Q-G-G-I-F-S-V-A-G-I-E-G-T-Q-L-A-H-C-L-G-A-Y-C-P-N-I-L-F-P-Y-A-R-E-C-I-T-S-L-V-S-R-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-M-N-Y-L-Q-Q-Q-A-E-G-E-V-E-G-V-E-Q-R-Q-D-A"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-D-A-V-E-K-I-G-N-R-F-D-L-V-L-V-A-A-R-R-A-R-Q-I-Q-S-G-G-K-D-A-L-V-P-E-E-N-D-K-V-T-V-I-A-L-R-E-I-E-E-G-L-I-T-N-Q-I-L-D-V-R-E-R-Q-E-Q-Q-E-Q-Q-A-A-E-I-Q-A-V-T-A-I-A-E-G-R-R"} +{"text": "### FUNCTION A GTPase-activating protein that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-K-Q-P-N-K-A-P-R-A-N-I-A-A-P-K-G-T-A-T-P-K-R-R-R-K-T-R-D-E-L-D-A-E-A-R-D-R-K-R-Q-K-K-H-S-G-N-R-S-G-A-R-T-N-V-E-G-S-N-K-K-G-H-S-Q-T-Q-E-K-D-P-R-V-G-S-K-V-P-V-P-L-V-I-E-S-Q-V-K-A-K-S-M-P-K-P-V-E-K-N-V-V-K-P-R-L-T-P-E-E-E-L-A-K-L-E-N-D-E-R-L-D-A-L-L-D-R-L-D-N-D-E-V-L-N-K-E-D-Q-A-Y-V-D-L-T-L-D-R-I-D-A-L-M-E-Q-L-G-I-E-L-G-D-D-E-D-D-V-E-R-E-E-K-Q-E-D-I-L-Q-L-L-K-R-G-N-P-K-D-T-F"} +{"text": "### FUNCTION Involved in succinate export with YjjP Both proteins are required for export ### SEQUENCE -M-G-I-I-D-F-L-L-A-L-M-Q-D-M-I-L-S-A-I-P-A-V-G-F-A-M-V-F-N-V-P-H-R-A-L-P-W-C-A-L-L-G-A-L-G-H-G-S-R-M-L-M-M-S-A-G-F-N-I-E-W-S-T-F-M-A-S-L-L-V-G-S-I-G-I-Q-W-S-R-W-Y-L-A-H-P-K-V-F-T-V-A-A-V-I-P-M-F-P-G-I-S-A-Y-T-A-M-I-S-A-V-K-I-S-H-L-G-Y-S-E-P-M-M-I-T-L-L-T-N-F-L-K-A-S-S-I-V-G-A-L-S-I-G-L-S-V-P-G-L-W-L-Y-R-K-R-P-R-V"} +{"text": "### FUNCTION Involved in the degradation and recycling of damaged RNA It is itself a target for degradation by the ATP-dependent protease Lon ### SEQUENCE -M-T-T-V-H-S-I-A-D-P-C-D-P-E-V-S-P-T-N-N-R-H-L-T-V-S-Y-A-S-R-Y-P-D-Y-T-R-I-P-A-L-T-M-K-G-Q-W-L-E-A-A-G-F-A-T-G-T-E-V-D-V-R-V-M-N-G-C-I-V-L-T-A-Q-Q-P-Q-P-E-E-S-E-L-M-Q-S-L-R-Q-V-S-K-L-S-A-R-K-Q-K-Q-V-Q-A-F-I-D-V-M-A-G-S-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-D-K-V-A-N-L-G-S-L-G-D-Q-V-N-V-K-A-G-Y-A-R-N-F-L-V-P-K-G-K-A-V-P-A-T-K-K-N-V-E-Y-F-E-A-R-R-A-E-L-E-A-K-L-A-D-V-L-A-A-A-N-A-R-A-E-K-I-N-A-L-E-T-V-T-I-A-S-K-A-G-D-E-G-K-L-F-G-S-I-G-T-R-D-I-A-D-A-V-T-A-A-G-V-D-V-A-K-S-E-V-R-L-P-N-G-V-L-R-T-T-G-E-H-E-V-N-F-Q-V-H-S-E-V-F-A-K-V-I-I-N-V-V-A-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-Y-F-R-R-R-K-F-C-R-F-T-A-E-G-V-Q-E-I-D-Y-K-D-I-A-T-L-K-N-Y-I-T-E-S-G-K-I-V-P-S-R-I-T-G-T-R-A-K-Y-Q-R-Q-L-R-R-A-I-K-R-A-R-Y-L-S-L-L-P-Y-T-D-R-H-Q"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site During primosome assembly it facilitates the complex formation between PriA and DnaT ### SEQUENCE -M-T-N-R-L-A-L-S-G-T-V-C-R-A-P-L-R-K-V-S-P-S-G-I-P-H-C-Q-F-V-L-E-H-R-S-V-Q-E-E-A-G-F-H-R-Q-A-W-C-Q-M-P-V-I-V-S-G-H-E-N-Q-A-I-T-H-S-I-T-V-G-S-R-I-T-V-Q-G-F-I-S-C-H-K-A-K-N-G-L-S-K-M-V-L-H-A-E-Q-I-E-L-I-D-S-G-D"} +{"text": "### FUNCTION The phosphoenolpyruvate-dependent sugar phosphotransferase system , a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane The enzyme II UlaABC PTS system is involved in ascorbate transport ### SEQUENCE -M-K-L-R-D-S-L-A-E-N-N-S-I-R-L-Q-A-E-A-N-T-W-Q-E-A-V-K-I-G-V-D-L-L-V-A-A-D-V-V-E-P-R-Y-Y-Q-A-I-L-D-G-V-E-Q-F-G-P-Y-F-V-I-A-P-G-L-A-M-P-H-G-R-P-E-E-G-V-K-K-T-G-F-S-L-V-T-L-K-K-P-L-E-F-N-H-E-D-N-D-P-V-D-I-L-I-T-M-A-A-V-D-A-N-T-H-Q-E-V-G-I-M-Q-I-V-N-L-F-E-D-E-A-N-F-D-R-L-R-A-C-R-T-A-Q-E-V-L-D-L-I-D-R-T-N-A-A-A"} +{"text": "### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-L-E-V-F-E-K-L-E-A-K-V-Q-Q-A-I-D-T-I-T-L-L-Q-M-E-I-E-E-L-K-E-K-N-N-S-L-T-Q-E-V-Q-S-A-Q-H-Q-R-E-E-L-E-R-E-N-N-S-L-K-E-Q-Q-S-G-W-Q-E-R-L-Q-A-L-L-G-R-M-E-E-V"} +{"text": "### FUNCTION Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE Its activity is ATP-independent ### SEQUENCE -M-R-N-Y-D-L-S-P-L-L-R-Q-W-I-G-F-D-K-L-A-N-A-L-Q-N-S-G-E-S-Q-S-F-P-P-Y-N-I-E-K-S-D-D-N-H-Y-R-I-T-L-A-L-A-G-F-R-Q-E-D-L-D-I-Q-L-E-G-T-R-L-T-V-K-G-T-P-E-Q-P-E-N-E-P-K-W-L-H-Q-G-L-V-M-Q-P-F-S-L-S-F-T-L-A-E-N-M-E-V-S-G-A-T-F-T-N-G-L-L-H-I-D-L-T-R-N-E-P-E-T-I-A-P-Q-R-I-A-I-N-E-R-S-A-L-N-S"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-A-Y-K-H-I-L-I-A-V-D-L-S-P-E-S-K-V-L-V-E-K-A-V-S-M-A-R-P-Y-N-A-K-I-S-L-I-H-V-D-V-N-Y-S-D-L-Y-T-G-L-I-D-V-N-L-G-D-M-Q-K-R-I-S-E-E-T-H-H-A-L-T-E-L-S-T-N-A-G-Y-P-I-T-E-T-L-S-G-S-G-D-L-G-Q-V-L-V-D-A-I-K-K-Y-D-M-D-L-V-V-C-G-H-H-Q-D-F-W-S-K-L-M-S-S-A-R-Q-L-I-N-T-V-H-V-D-M-L-I-V-P-L-R-D-E-E-E"} +{"text": "### FUNCTION May be involved in an alternative pathway for phosphopantetheinyl transfer and holo-ACP synthesis The native apo-protein substrate is unknown ### SEQUENCE -M-Y-Q-V-V-L-G-K-V-S-T-L-S-A-G-Q-L-P-D-A-L-I-A-Q-A-P-Q-G-V-R-R-A-S-W-L-A-G-R-V-L-L-S-R-A-L-S-P-L-P-E-M-V-Y-G-E-Q-G-K-P-A-F-S-A-G-A-P-L-W-F-N-L-S-H-S-G-D-T-I-A-L-L-L-S-D-E-G-E-V-G-C-D-I-E-V-I-R-P-R-D-N-W-R-S-L-A-N-A-V-F-S-L-G-E-H-A-E-M-E-A-E-R-P-E-Q-Q-L-A-A-F-W-R-I-W-T-R-K-E-A-I-V-K-Q-R-G-G-S-A-W-Q-I-V-S-V-D-S-T-L-P-S-A-L-S-V-S-Q-C-Q-L-D-T-L-S-L-A-V-C-T-P-T-P-F-T-L-T-P-Q-T-I-T-K-A-L"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-R-I-S-D-A-A-Q-A-H-F-A-K-L-L-A-N-Q-E-E-G-T-Q-I-R-V-F-V-I-N-P-G-T-P-N-A-E-C-G-V-S-Y-C-P-P-D-A-V-E-A-T-D-T-A-L-K-F-D-L-L-T-A-Y-V-D-E-L-S-A-P-Y-L-E-D-A-E-I-D-F-V-T-D-Q-L-G-S-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-A-D-D-A-P-L-M-E-R-V-E-Y-A-L-Q-S-Q-I-N-P-Q-L-A-G-H-G-G-R-V-S-L-M-E-I-T-D-E-G-Y-A-I-L-Q-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-E-G-I-E-K-Q-L-L-N-E-F-P-E-L-K-G-V-R-D-L-T-E-H-Q-R-G-E-H-S-Y-Y"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-K-T-P-L-I-T-R-E-G-Y-E-T-L-K-Q-E-L-N-Y-L-W-R-E-E-R-P-E-V-T-K-K-V-T-W-A-A-S-L-G-D-R-S-E-N-A-D-Y-Q-Y-N-K-K-R-L-R-E-I-D-R-R-V-R-Y-L-T-K-C-M-E-N-L-K-I-V-D-Y-S-P-Q-Q-E-G-K-V-F-F-G-A-W-V-E-I-E-N-D-D-G-D-R-L-K-F-R-I-V-G-Y-D-E-I-F-G-R-K-D-Y-I-S-I-D-S-P-M-A-R-A-L-L-K-K-E-V-G-D-L-A-V-V-N-T-P-V-G-E-A-N-W-Y-V-N-A-I-E-Y-V-K"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-R-Y-A-I-M-V-T-G-P-A-Y-G-T-Q-Q-A-S-S-A-L-Q-F-A-H-A-L-L-N-E-G-H-E-L-A-S-V-F-F-Y-R-E-G-V-Y-N-A-N-L-L-T-S-P-A-S-D-E-Y-D-L-V-R-A-W-Q-K-L-N-T-Q-H-G-V-A-L-N-I-C-V-A-A-A-L-R-R-G-I-I-D-E-T-E-A-G-R-L-A-L-P-S-A-N-L-Q-P-G-F-T-L-S-G-L-G-A-L-A-E-A-S-L-T-C-D-R-V-V-Q-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-K-R-I-A-F-V-F-S-T-A-P-H-G-S-A-S-G-R-E-G-L-D-A-L-L-A-T-S-A-L-T-E-A-L-G-V-F-F-I-S-D-G-V-F-Q-L-L-P-G-Q-K-P-D-A-V-L-A-R-D-Y-I-A-T-F-K-L-F-D-L-Y-D-I-D-Q-C-W-I-C-A-A-S-L-R-E-R-G-L-E-N-I-N-F-V-V-D-A-T-P-L-E-P-V-A-L-R-R-E-L-G-N-Y-D-V-I-L-R-F"} +{"text": "### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine at tRNA wobble positions ### SEQUENCE -M-L-H-T-L-P-H-C-A-S-S-V-D-F-P-A-L-L-R-L-L-K-E-G-D-A-L-L-L-L-Q-D-G-V-T-V-A-I-E-G-N-R-F-L-E-S-L-R-D-A-P-I-T-V-Y-A-L-K-E-D-I-D-A-R-G-L-G-G-Q-I-S-D-S-V-V-R-V-D-Y-T-E-F-V-R-L-T-V-K-Y-A-N-Q-M-A-W"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-A-V-I-A-L-T-S-I-Y-G-V-G-K-T-R-S-K-A-I-L-A-A-A-G-I-A-E-N-V-K-I-S-E-L-S-E-E-Q-I-D-T-L-R-D-E-V-A-K-F-V-V-E-G-D-L-R-R-E-I-S-M-S-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-E-F-G-R-P-Q-R-V-A-Q-E-M-Q-K-E-I-A-I-I-L-Q-R-E-I-K-D-P-R-L-G-M-M-T-T-V-S-G-V-E-M-S-R-D-L-A-Y-A-K-V-F-V-T-F-L-N-D-K-D-E-D-A-V-K-A-G-I-K-A-L-Q-E-A-S-G-F-I-R-S-L-L-G-K-A-M-R-L-R-I-V-P-E-L-T-F-F-Y-D-N-S-L-V-E-G-M-R-M-S-N-L-V-T-N-V-V-K-H-D-E-E-R-R-V-N-P-D-D-S-K-E-D"} +{"text": "### FUNCTION Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein ### SEQUENCE -M-L-E-R-I-K-V-C-F-T-E-S-I-Q-T-Q-I-A-A-A-E-A-L-P-D-A-I-S-R-A-A-M-T-L-V-H-S-L-L-N-G-N-K-I-L-C-C-G-N-G-T-S-A-A-N-A-Q-H-F-A-A-S-M-I-N-R-F-E-T-E-R-P-S-L-P-A-I-A-L-N-T-D-N-V-V-L-T-A-I-A-N-D-R-L-H-D-E-V-Y-A-K-Q-V-R-A-L-G-H-A-G-D-V-L-L-A-I-S-T-R-G-N-S-R-D-I-V-K-A-V-E-A-A-V-T-R-D-M-T-I-V-A-L-T-G-Y-D-G-G-E-L-A-G-L-L-G-P-Q-D-V-E-I-R-I-P-S-H-H-S-A-R-I-Q-E-M-H-M-L-T-V-N-C-L-C-D-L-I-D-N-T-L-F-P-H-Q-D-D"} +{"text": "### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway ### SEQUENCE -M-M-T-P-T-I-P-V-A-L-F-D-R-L-L-V-E-G-I-S-P-H-E-L-V-R-R-K-L-M-C-L-F-N-S-C-A-V-P-G-G-E-T-L-P-P-L-L-T-R-G-M-P-E-W-H-E-V-N-V-G-D-K-R-V-L-N-W-F-C-R-E-L-R-A-A-I-L-R-Y-E-P-S-I-N-M-L-K-V-S-V-K-D-A-H-H-Q-T-L-A-L-S-L-E-A-M-L-Q-D-E-S-E-P-L-R-L-E-I-A-Y-S-N-G-R-W-R"} +{"text": "### FUNCTION Is critically involved in promoting the replication of Styphimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages May be involved in the biosynthesis and modification of the peptidoglycan layer of the cell wall ### SEQUENCE -M-L-F-F-N-V-A-S-L-K-Y-K-H-H-E-S-I-Q-M-I-I-D-R-I-D-H-L-V-L-T-V-S-D-I-S-T-T-I-R-F-Y-E-E-V-L-G-F-S-A-V-T-F-K-Q-N-R-K-A-L-I-F-G-A-Q-K-I-N-L-H-Q-Q-E-M-E-F-E-P-K-A-S-R-P-T-P-G-S-A-D-L-C-F-I-T-S-T-P-I-N-D-V-V-S-E-I-L-Q-A-G-I-S-I-V-E-G-P-V-E-R-T-G-A-T-G-E-I-M-S-I-Y-I-R-D-P-D-G-N-L-I-E-I-S-Q-Y-V"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-G-T-L-L-A-F-D-F-G-T-K-S-I-G-V-A-I-G-Q-R-I-T-G-T-A-R-P-L-P-A-I-K-A-Q-D-G-T-P-D-W-T-L-I-E-R-L-L-K-E-W-Q-P-D-E-I-I-V-G-L-P-L-N-M-D-G-T-E-Q-P-L-T-A-R-A-R-K-F-A-N-R-I-H-G-R-F-G-V-T-V-T-L-H-D-E-R-L-S-T-V-E-A-R-S-G-L-F-E-R-G-G-Y-R-A-L-N-K-G-K-V-D-S-A-S-A-V-I-I-L-E-S-Y-F-E-Q-G-Y"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-V-P-A-E-L-K-Y-S-K-E-H-E-W-L-R-K-E-A-D-G-T-Y-T-V-G-I-T-E-H-A-Q-E-L-L-G-D-M-V-F-V-D-L-P-E-V-G-A-T-V-S-A-G-D-D-C-A-V-A-E-S-V-K-A-A-S-D-I-Y-A-P-V-S-G-E-I-V-A-V-N-D-A-L-S-D-S-P-E-L-V-N-S-E-P-Y-T-G-G-W-I-F-K-I-K-A-S-D-E-S-E-L-E-S-L-L-D-A-T-A-Y-E-A-L-L-E-D-E"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-S-E-P-T-S-R-R-P-A-Y-A-R-L-L-D-R-A-V-R-I-L-A-V-R-D-H-S-E-Q-E-L-R-R-K-L-S-A-P-V-M-G-K-N-G-P-E-E-I-D-A-T-A-D-D-Y-E-R-V-I-A-W-C-H-E-H-H-Y-L-D-D-E-R-F-V-M-R-F-I-A-S-R-S-R-K-G-Y-G-P-A-R-I-R-Q-E-L-N-Q-K-G-I-S-R-E-S-T-E-K-A-M-R-E-C-E-I-D-W-S-E-M-A-R-E-Q-A-V-R-K-Y-G-E-P-L-P-S-N-F-S-E-K-V-K-V-Q-R-F-L-L-Y-R-G-Y-L-M-D-N-I-Q-Q-I-W-R-N-F-A-D"} +{"text": "### FUNCTION Exports L-alanine ### SEQUENCE -M-F-S-P-Q-S-R-L-R-H-A-V-A-D-T-F-A-M-V-V-Y-C-S-V-V-N-M-L-I-E-I-F-L-S-G-M-S-F-E-Q-S-L-S-S-R-L-V-A-I-P-V-N-I-L-I-A-W-P-Y-G-V-Y-R-D-L-I-M-R-V-A-R-K-A-S-P-A-G-W-A-K-N-L-A-D-V-L-A-Y-V-T-F-Q-S-P-V-Y-I-I-I-L-L-T-V-G-A-G-W-H-Q-I-V-A-A-V-S-S-N-I-V-V-S-M-L-M-G-A-V-Y-G-Y-F-L-D-Y-C-R-R-L-F-K-V-S-S-Y-H-Q-A-K-A"} +{"text": "### FUNCTION Exporter of O-acetylserine and cysteine ### SEQUENCE -M-T-P-M-L-L-S-A-F-W-T-Y-T-L-I-T-A-L-T-P-G-P-N-N-I-L-A-L-S-A-A-T-A-H-G-F-R-Q-S-I-R-V-L-A-G-M-S-L-G-F-L-V-V-M-L-L-C-A-G-I-A-F-S-L-A-V-I-D-P-A-I-I-H-L-L-S-W-V-G-A-A-Y-I-L-W-L-A-W-K-I-A-T-S-P-A-A-D-E-N-A-R-P-K-P-V-G-F-W-V-S-F-G-L-Q-F-V-N-V-K-I-I-L-Y-G-I-T-A-L-S-T-F-V-L-P-Q-T-Q-A-L-N-W-V-I-G-V-S-I-L-L-A-L-I-G-T-F-G-N-V-C-W-A-L-A-G-H-L-F-Q-R-A-F-R-H-Y-G-R-Q-L-N-I-I-L-A-L-L-L-V-Y-C-A-V-R-I-F-Y"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-D-Y-F-T-L-F-G-L-P-A-R-Y-Q-I-D-T-Q-A-L-S-L-R-F-Q-D-L-Q-R-Q-Y-H-P-D-K-F-A-N-G-T-Q-A-Q-Q-L-A-A-V-Q-Q-S-A-T-I-N-Q-A-W-Q-T-L-R-H-P-L-T-R-A-E-Y-L-L-S-L-H-G-F-D-L-A-S-E-Q-H-T-V-R-D-T-A-F-L-M-E-Q-L-T-L-R-E-E-L-D-D-I-E-Q-S-K-D-D-A-R-L-E-S-F-I-K-R-V-Q-K-M-F-D-A-R-L-Q-Q-M-V-E-Q-L-D-N-A-A-W-D-A-A-A-D-T-V-R-K-L-R-F-L-D-K-L-R-S-S-A-E-Q-L-E-E-K-L-L-D-F"} +{"text": "### FUNCTION General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases ### SEQUENCE -M-K-M-F-V-P-A-V-V-F-A-A-L-A-S-A-S-A-W-A-N-N-G-D-T-A-Q-P-L-E-K-I-A-P-Y-P-Q-A-E-K-G-M-K-R-Q-V-I-T-L-T-P-Q-Q-D-E-S-T-L-K-V-E-L-L-I-G-Q-T-L-N-V-D-C-N-Q-H-R-L-G-G-T-L-E-T-K-T-L-E-G-W-G-Y-D-Y-Y-V-F-D-N-V-T-S-P-V-S-T-M-M-A-C-P-E-G-K-K-E-Q-K-F-V-T-A-W-L-G-E-D-G-M-L-R-Y-N-S-K-L-P-I-V-V-Y-T-P-A-N-V-D-V-K-Y-R-I-W-K-A-D-A-N-V-Q-N-A-V-A-R"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-H-F-T-A-T-V-L-L-A-F-G-M-S-M-D-A-F-A-A-S-I-G-K-G-A-T-L-H-K-P-K-F-S-E-A-L-R-T-G-L-I-F-G-A-V-E-T-L-T-P-L-I-G-W-G-L-G-I-L-A-S-K-F-V-L-E-W-N-H-W-I-A-F-V-L-L-I-F-L-G-G-R-M-I-I-E-G-I-R-G-G-S-D-E-D-E-T-P-L-R-R-H-S-F-W-L-L-V-T-T-A-I-A-T-S-L-D-A-M-A-V-G-V-G-L-A-F-L-Q-V-N-I-I-A-T-A-L-A-I-G-C-A-T-L-I-M-S-T-L-G-M-M-I-G-R-F-I-G-P-M-L-G-K-R-A-E-I-L-G-G-V-V-L-I-G-I-G-V-Q-I-L-W-T-H-F-H-G"} +{"text": "### FUNCTION Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues ### SEQUENCE -M-P-I-S-I-C-K-H-G-A-P-F-V-V-Q-H-E-N-R-Y-G-S-G-A-S-Q-S-S-S-L-S-K-S-I-R-H-I-S-N-S-H-E-E-I-K-F-I-S-C-Y-S-A-N-G-A-C-F-S-N-A-Q-M-L-A-N-A-S-G-R-P-V-I-G-Y-Y-G-K-I-N-K-L-T-A-S-L-D-N-S-G-R-I-F-R-P-Q-H-K-L-A-A-N-I-C-Y-V-G-N-R-L-L-S-A-P-V-Q-L-G-F-G-L-K-H-L-L-T-C-H-S-N-G-N-V-R"} +{"text": "### FUNCTION Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring ### SEQUENCE -M-D-I-R-Q-M-N-R-T-H-L-D-H-W-R-G-L-R-K-Q-L-W-P-G-H-P-D-D-A-H-L-A-D-G-E-E-I-L-Q-A-D-H-L-A-S-F-I-A-M-A-D-G-V-A-I-G-F-A-D-A-S-I-R-H-D-Y-V-N-G-C-D-S-S-P-V-V-F-L-E-G-I-F-V-L-P-S-F-R-Q-R-G-V-A-K-Q-L-I-A-A-V-Q-R-W-G-T-N-K-G-C-R-E-M-A-S-D-T-S-P-E-N-T-I-S-Q-K-V-H-Q-A-L-G-F-E-E-T-E-R-V-I-F-Y-R-K-R-C"} +{"text": "### FUNCTION Required for growth and/or survival at acidic conditions ### SEQUENCE -M-K-K-V-L-A-L-V-V-A-A-A-M-G-L-S-S-A-A-F-A-A-E-T-A-T-P-A-K-T-A-A-P-A-K-T-T-Q-T-T-Q-H-H-K-K-Q-H-K-K-T-V-E-Q-K-A-Q-A-A-K-K-H-Q-K-K-G-G-K-A-P-A-K-T-T-S-K-P-T-T-Q-P-A-A"} +{"text": "### FUNCTION Participates in cysteine desulfuration mediated by SufS Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process ### SEQUENCE -M-A-A-L-P-D-K-E-K-L-L-R-N-F-T-R-C-A-N-W-E-E-K-Y-L-Y-I-I-E-L-G-Q-R-L-A-E-L-N-P-Q-D-R-N-P-Q-N-T-I-H-G-C-Q-S-Q-V-W-I-V-M-R-R-N-A-N-G-I-I-E-L-Q-G-D-S-D-A-A-I-V-K-G-L-M-A-V-V-F-I-L-Y-H-Q-M-T-A-Q-D-I-V-H-F-D-V-R-P-W-F-E-K-M-A-L-A-Q-H-L-T-P-S-R-S-Q-G-L-E-A-M-I-R-A-I-R-A-K-A-A-T-L-S"} +{"text": "### FUNCTION Activates the cell division inhibited by chromosomal DNA over-replication ### SEQUENCE -M-M-K-P-L-R-Q-Q-N-R-Q-I-I-S-Y-I-P-R-V-E-P-A-P-P-E-H-A-I-K-M-D-T-F-R-D-V-W-I-L-R-G-K-Y-V-A-F-V-L-T-R-E-S-F-Q-R-S-P-A-F-S-V-P-E-S-A-Q-R-W-A-N-Q-V-R-Q-E-N-E-I-A-D"} +{"text": "### FUNCTION Required for spatial organization of the terminus region of the chromosome during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-Q-L-E-N-L-E-S-G-W-K-W-K-Y-L-V-K-K-H-R-E-G-E-L-I-T-R-Y-V-E-A-S-A-A-Q-E-A-V-N-L-L-L-A-L-E-N-E-P-V-R-V-N-V-W-I-D-R-H-M-N-P-A-L-L-N-R-M-K-Q-T-I-R-A-R-R-K-R-H-F-N-A-E-H-Q-H-T-R-K-K-S-I-D-L-E-F-M-V-W-Q-R-L-A-G-L-A-Q-R-R-G-K-T-L-S-E-T-I-V-Q-L-I-E-D-A-E-H-K-E-K-Y-A-T-Q-M-T-T-L-K-Q-D-L-Q-A-L-L-G-K-K"} +{"text": "### FUNCTION Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ ### SEQUENCE -M-R-I-K-P-D-D-N-W-R-W-Y-Y-D-E-E-H-D-R-M-M-L-D-L-A-N-G-M-L-F-R-S-R-F-S-R-K-M-L-T-P-D-A-F-C-P-T-G-F-C-V-D-D-A-A-L-Y-F-S-F-E-E-K-C-R-D-F-E-L-T-K-E-Q-R-A-E-L-V-L-N-A-L-V-A-I-R-Y-L-K-P-Q-M-P-K-S-W-H-F-V-A-H-G-E-M-W-T-P-G-T-G-D-A-A-S-V-W-L-S-D-T-A-E-Q-V-N-L-L-V-V-E-P-G-E-N-A-A-L-C-L-L-A-Q-P-G-V-V-I-A-G-R-T-M-Q-L-G-D-A-I-K-I-M-N-D-R-L-K-P-Q-V-H-C-H-S-F-S-L-E-Q-A-V"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-I-G-L-R-P-A-F-S-T-M-L-F-L-L-L-L-T-G-G-V-Y-P-L-L-T-T-A-L-G-Q-W-W-F-P-W-Q-A-N-G-S-L-I-H-K-D-N-V-I-R-G-S-A-L-I-G-Q-S-F-T-A-A-G-Y-F-H-G-R-P-S-A-T-A-D-T-P-Y-N-P-L-A-S-G-G-S-N-L-A-A-S-N-P-E-L-D-A-Q-I-Q-A-R-V-A-A-L-R-A-A-N-P-Q-A-S-S-A-V-P-V-E-L-A-T-A-S-A-S-G-L-D-N-N-L-T-P-G-A-A-A-W-Q-I-P-R-V-A-A-A-R-Q-L-P-V-E-Q-V-A-Q-L-V-A-E-Y-T-H-R-P-L-A-R-F-L-G-Q-P-V-V-N-I-V-E-L-N-L-A-L-D-A-L-Q-G-H-R-A-K"} +{"text": "### FUNCTION Low-potential electron donor to a number of redox enzymes alamin in methionine synthase ### SEQUENCE -M-A-I-T-G-I-F-F-G-S-D-T-G-N-T-E-N-I-A-K-M-I-Q-K-Q-L-G-K-D-V-A-D-V-H-D-I-A-K-S-S-K-E-D-L-E-G-Y-D-I-L-L-L-G-I-P-T-W-Y-Y-G-E-A-Q-C-D-W-D-D-F-F-P-T-L-E-E-I-D-F-N-G-K-L-V-A-L-F-G-C-G-D-Q-E-D-Y-A-E-Y-F-C-D-A-L-G-T-I-R-D-I-I-E-P-R-G-A-T-I-V-G-H-W-P-T-A-G-Y-H-F-E-A-S-K-G-L-A-D-D-D-H-F-V-G-L-A-I-D-E-D-R-Q-P-E-L-T-A-E-R-V-E-K-W-V-K-Q-V-S-A-E-L-H-L-D-D-I-L-N-A"} +{"text": "### FUNCTION Required for optimal enterobactin synthesis Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules ### SEQUENCE -M-I-W-K-R-H-L-T-L-D-E-L-N-A-T-S-Q-N-T-L-V-A-H-L-G-I-V-Y-T-R-L-G-D-D-V-L-E-A-E-M-P-V-D-A-R-T-H-Q-P-F-G-L-L-H-G-G-A-S-A-A-L-A-E-T-L-G-S-M-A-G-Y-L-M-T-R-D-G-Q-C-V-V-G-T-E-L-N-A-T-H-H-R-A-I-S-Q-G-K-V-R-G-V-C-L-P-L-H-L-G-R-Q-N-Q-S-W-E-I-T-L-F-D-E-Q-G-R-R-C-C-T-C-R-L-G-T-A-V-M-G"} +{"text": "### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate -ureidoglycolate, generating urea and glyoxylate Involved in the utilization of allantoin as nitrogen source ### SEQUENCE -M-K-L-E-V-L-P-L-D-Q-K-T-F-S-A-Y-G-D-V-I-E-T-Q-E-R-E-F-F-H-I-N-N-G-L-V-E-R-Y-H-D-L-A-K-V-E-V-L-E-Q-D-R-T-L-I-S-I-N-R-A-Q-P-A-A-M-P-I-V-V-H-E-L-E-R-H-P-L-G-T-Q-A-F-V-P-M-N-G-E-A-F-V-V-I-V-A-L-G-D-D-K-P-D-L-S-T-L-R-A-F-I-S-N-G-R-Q-G-V-N-Y-H-R-N-V-W-H-H-P-L-F-A-W-Q-T-V-T-D-F-L-T-V-D-R-G-G-S-D-N-C-D-V-E-S-I-P-T-H-E-L-C-F-A"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-A-T-A-Q-Q-L-E-F-L-K-N-S-I-K-S-I-Q-D-Y-P-K-P-G-I-L-F-R-D-V-T-S-L-L-E-D-P-K-A-Y-A-L-S-I-E-L-L-V-E-R-Y-K-N-A-G-I-T-K-V-V-G-T-E-A-R-G-F-L-F-G-A-P-V-A-L-G-L-G-V-G-F-V-P-V-R-K-P-R-K-L-P-R-E-T-I-A-E-T-Y-E-L-E-Y-G-T-D-Q-L-E-I-H-V-D-A-I-K-P-G-D-N-V-L-V-V-D-D-L-L-A-T-G-G-T-I-E-A-T-V-K-L-I-R-R-L-G-G-K-V-T-D-A-A-F-I-I-N-L-F-D-L-G-G-E-Q-R-L-E-K-Q-G-I-T-C-Y-S-L-V-P-F-P-G-H"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-P-A-A-R-R-R-A-R-E-C-A-V-Q-A-L-Y-S-W-Q-L-S-Q-N-D-I-A-D-V-E-Y-Q-F-L-A-E-Q-D-V-K-D-V-D-V-L-Y-F-R-E-L-L-S-G-V-A-T-N-S-A-Y-L-D-G-L-M-K-P-Y-L-S-R-L-L-E-E-L-G-Q-V-E-K-A-V-L-R-I-A-L-F-E-L-S-K-R-S-D-V-P-Y-K-V-A-I-N-E-A-I-E-L-A-K-T-F-G-A-E-D-S-H-K-F-V-N-G-V-L-D-K-A-A-P-V-I-R-P-N-K-K"} +{"text": "### FUNCTION Regulates secA expression by translational coupling of the secM secA operon Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation ### SEQUENCE -M-S-G-I-L-T-R-W-R-Q-L-G-R-R-Y-F-W-P-H-L-L-L-G-M-V-A-A-S-F-G-L-P-A-L-S-N-A-A-E-T-N-T-P-A-R-T-T-A-S-T-A-S-K-V-N-F-S-H-F-A-L-L-E-A-S-N-R-R-P-N-F-T-V-D-Y-W-H-Q-H-A-I-R-T-V-I-R-H-L-S-F-A-M-A-P-Q-T-L-P-V-A-D-A-P-S-P-L-Q-A-H-H-I-A-L-L-N-T-L-S-A-M-L-T-Q-E-G-T-P-P-A-I-V-R-R-L-S-L-A-Y-F-A-P-Q-T-A-F-S-I-P-A-W-I-S-Q-A-Q-G-I-R-A-G-P-Q-R-L-S"} +{"text": "### FUNCTION Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall gene cluster Acts by binding directly to DNA May also regulate the expression of genes outside the dcw cluster ### SEQUENCE -M-F-R-G-A-T-L-V-N-L-D-S-K-G-R-L-T-V-P-T-R-Y-R-E-Q-L-I-E-S-A-T-G-Q-M-V-C-T-I-D-I-H-H-P-C-L-L-L-Y-P-L-P-E-W-E-I-I-E-Q-K-L-S-R-L-S-S-M-N-P-V-E-R-R-V-Q-R-L-L-L-G-H-A-S-E-C-Q-M-D-G-A-G-R-L-L-I-A-P-V-L-R-Q-H-A-G-L-T-K-E-V-M-L-V-G-Q-F-N-K-F-E-L-W-D-E-T-T-W-Y-Q-Q-V-K-E-D-I-D-A-E-Q-S-A-T-E-T-L-S-E-R-L-Q-D-L-S-L"} +{"text": "### FUNCTION Could be part of an electron transfer system required for anaerobic carnitine reduction Could be a 3Fe-4S cluster-containing protein ### SEQUENCE -M-T-S-P-V-N-V-D-V-K-L-G-V-N-K-F-N-V-D-E-D-S-P-H-I-I-L-K-T-D-P-D-K-Q-A-L-E-V-L-I-K-A-C-P-A-G-L-Y-K-K-Q-D-D-G-S-V-R-F-D-Y-A-G-C-L-E-C-G-T-C-R-I-L-G-L-D-T-A-L-E-K-W-E-Y-P-R-G-T-F-G-V-E-F-R-Y-G"} +{"text": "### FUNCTION Overproduction of CaiE stimulates the activity of CaiB and CaiD ### SEQUENCE -M-S-Y-Y-A-F-E-G-L-I-P-V-V-H-P-D-A-F-V-H-P-S-A-V-L-I-G-D-V-I-V-G-A-G-V-Y-I-G-P-L-A-S-L-R-G-D-Y-G-R-L-I-L-E-A-G-S-N-L-Q-D-G-C-I-M-H-G-Y-C-D-T-D-T-I-V-H-E-N-G-H-I-G-H-G-A-I-L-H-G-C-V-V-G-R-D-A-L-V-G-M-N-S-V-I-M-D-G-A-V-I-G-E-E-S-I-V-A-A-M-S-F-V-K-A-G-F-Q-G-E-A-R-Q-L-L-V-G-S-P-A-R-V-L-R-Q-V-T-D-Q-E-L-H-W-K-H-L-N-T-K-E-Y-Q-D-L-A-I-R-C-R-T-G-L-S-E-T-K-P-L-T-Q-A-E-E-N-R-P-R-L-K-G-T-T-D-V-K-P-K-S-A-Q"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-P-S-W-K-E-L-V-L-V-K-G-H-P-M-Q-R-I-Y-I-E-K-V-V-V-N-I-G-V-G-A-S-G-E-K-L-E-K-A-A-G-L-L-K-E-L-T-G-A-E-P-S-R-R-R-A-K-K-S-I-K-D-F-G-I-R-K-G-E-P-I-G-V-A-V-T-L-R-R-D-Q-A-V-N-F-L-M-R-A-L-Q-A-V-N-N-R-V-K-K-T-S-F-D-D-R-G-N-V-C-F-G-I-K-E-H-I-L-L-P-G-V-K-Y-D-P-A-V-G-I-W-G-M-D-V-C-V-K-L-A-K-P-G-L-R-V-Q-L-R-R-R-R-R-S-K-V-G-K-R-Q-L-V-T-K-E-E-A-I-E-F-F-Q-K-V-L-G-V-Q-V-D"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-V-R-R-F-K-R-G-T-K-Y-R-R-G-S-R-T-H-G-W-G-R-V-G-Q-H-R-K-S-G-G-S-G-G-K-G-M-V-G-F-H-K-H-K-W-S-L-V-M-K-Y-G-E-S-G-T-G-W-P-F-Y-G-K-H-G-F-K-Q-P-P-P-I-S-I-E-W-R-P-I-N-V-G-T-L-A-E-L-V-K-E-L-K-A-E-G-K-V-R-E-E-G-G-K-Y-V-I-N-L-L-E-L-G-F-N-K-L-L-G-G-G-T-I-D-L-P-V-I-V-Y-T-P-I-A-S-R-T-A-V-E-K-I-E-K-A-G-G-E-V-R-I-I-H-V-I-H-R"} +{"text": "### FUNCTION Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP ### SEQUENCE -M-K-K-K-G-G-R-I-L-W-L-V-Y-I-D-A-S-V-P-R-S-R-G-R-V-L-P-R-G-L-A-V-E-K-P-S-L-K-E-V-V-Q-A-L-E-E-L-G-Y-K-F-Q-V-F-P-D-K-K-Y-P-P-L-W-F-E-E-K-W-G-Y-V-V-V-E-T-N-E-K-I-R-E-I-A-S-K-V-A-G-K-I-R-E-M-R-R"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-F-T-T-S-A-Q-P-R-K-Q-R-R-S-L-Y-K-A-P-L-H-L-R-R-K-L-F-N-A-K-L-S-P-E-L-A-K-K-L-G-V-K-R-L-P-V-R-R-G-D-T-V-L-I-L-R-G-D-F-K-G-V-T-G-K-V-V-K-V-D-L-K-R-V-R-I-Y-V-E-G-A-T-R-T-N-S-R-G-Q-T-V-Y-Y-P-I-H-P-S-K-V-M-I-V-D-V-D-L-S-D-K-A-R-Q-K-I-I-E-R-R-K-K-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-V-R-L-A-I-V-V-A-E-F-N-Y-D-I-T-Q-L-M-L-Q-K-A-V-E-H-A-K-F-L-G-A-E-I-T-Y-I-V-K-T-P-G-V-Y-D-I-P-M-I-L-K-E-L-V-A-K-E-E-V-D-A-V-A-T-L-G-A-V-I-Q-G-A-T-K-H-D-E-L-V-A-T-Q-A-A-R-K-I-L-D-I-A-V-E-S-G-K-P-I-T-L-G-I-I-G-H-G-A-N-R-I-Q-A-L-E-R-V-E-E-Y-A-R-R-A-V-E-A-A-V-K-M-A-R-R-K-K-A-L-R-E-A-K-Y-N-G-S-T-V-Y-I-D"} +{"text": "### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-T-W-R-E-R-A-E-L-R-I-G-I-S-G-M-P-G-V-G-K-T-T-L-V-L-K-I-A-E-L-A-R-S-R-V-K-V-C-G-F-V-T-V-E-V-R-E-G-G-T-R-I-G-F-D-V-V-D-L-A-N-G-R-R-M-A-L-A-R-V-G-R-G-E-P-S-V-G-K-Y-V-V-N-L-E-A-C-N-V-I-S-E-A-L-R-R-E-C-D-L-K-I-I-D-E-I-G-A-M-E-F-K-C-K-N-F-G-E-D-L-Q-T-A-L-H-T-S-P-R-V-I-A-T-V-H-R-N-Y-I-D-I-A-K-K-L-G-L-E-I-I-W-L-T-R-E-N-W-G-L-V-F-R-Q-L-L-I-Q-L-G-L-T-Q"} +{"text": "### FUNCTION Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A ### SEQUENCE -M-E-V-V-K-D-I-A-E-S-Y-G-A-E-R-I-Y-T-V-G-D-V-V-T-Q-N-F-F-K-H-G-L-I-P-T-S-A-A-V-D-E-K-T-R-R-G-V-R-I-E-Q-L-A-V-F-K-R-V-I-K-V-N-N-P-P-G-Y-I-T-E-E-A-W-S-A-V-E-E-A-V-R-G-G-V-I-I-K-V-E-G-E-E-D-M-L-S-L-A-F-I-K-L-A-P-P-K-S-I-V-A-Y-G-H-Y-L-G-A-L-I-A-L-P-V-D-W-Y-K-E-Y-V-L-K-L-F-D-Y-L-E-K-C"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-S-E-E-L-L-V-S-K-I-E-N-G-T-V-I-D-H-I-P-A-G-R-A-L-T-V-L-R-I-L-G-I-S-G-K-E-G-L-R-V-A-L-V-M-N-V-E-S-K-K-L-G-K-K-D-I-V-K-I-E-G-R-E-L-T-P-E-E-V-N-I-I-S-A-V-A-P-T-A-T-I-N-I-I-R-N-F-A-V-V-K-K-F-K-V-T-P-P-D-V-I-R-G-R-F-K-C-K-N-P-T-C-V-T-N-A-P-R-E-P-V-E-P-T-F-Y-L-V-R-R-E-P-P-L-F-I-C-A-Y-C-G-R-Y-H-E-L-G-D-L-L"} +{"text": "### FUNCTION Located on the platform of the 30S subunit ### SEQUENCE -M-S-S-E-Q-Q-K-L-R-W-G-I-A-W-I-Y-S-S-S-N-N-T-I-I-T-I-T-D-L-T-G-A-E-T-V-A-R-V-S-G-G-Q-V-V-R-A-D-K-D-K-P-S-P-W-A-A-M-Q-A-A-Y-K-A-A-Q-L-A-L-A-R-G-I-N-A-V-H-I-K-V-R-G-P-G-G-Y-G-M-K-V-P-G-P-G-A-S-A-A-I-R-A-L-A-R-S-G-L-V-I-G-R-I-E-D-V-T-P-I-P-H-D-I-I-R-P-P-S-G-R-K-G-R-R-V"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-A-K-R-G-G-K-R-T-V-G-V-P-Y-R-F-H-V-T-P-G-I-F-M-N-S-L-V-P-V-A-D-N-S-G-A-K-L-V-R-V-I-G-V-V-G-H-Y-S-K-T-V-H-R-R-I-P-G-A-G-V-G-D-M-V-V-V-V-V-R-E-G-K-P-E-L-R-K-Q-I-F-R-A-I-V-V-R-Q-R-R-P-Y-R-R-P-D-G-T-W-V-A-F-E-D-N-A-V-V-I-V-T-P-E-G-D-P-K-G-S-E-I-H-G-P-V-A-M-E-A-T-L-R-W-P-T-I-A-N-L-A-S-I-V-V"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-S-K-R-V-V-T-V-P-L-Q-G-G-K-V-A-V-N-P-Q-F-Q-D-A-L-K-Q-I-G-L-D-P-N-A-V-V-Q-R-V-Q-E-E-L-K-K-V-G-K-Y-P-V-Q-K-V-E-V-E-V-V-S-P-S-K-Y-E-V-K-I-Y-L-P-P-I-G-D-L-L-L-K-L-F-G-K-D-T-G-A-H-D-A-R-N-E-V-I-G-N-L-S-F-A-Q-L-V-E-I-A-L-L-K-K-D-E-L-K-S-K-T-L-K-S-A-V-K-Q-L-L-S-T-C-K-A-M-G-V-T-V-D-G-R-K-A-E-E-V-L-R-D-V-D-G-G-K-Y-D-E-I-I-N-K-F-E-K-Q-W-Q-Q"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-S-R-Q-D-V-Q-R-L-L-E-E-Y-Q-L-I-G-E-L-L-S-S-L-Q-A-Q-H-A-T-V-A-E-L-L-E-E-L-T-T-A-L-D-G-V-R-L-L-K-G-E-G-G-E-R-L-V-H-I-G-A-G-L-F-V-K-G-V-F-E-A-K-E-V-L-A-P-L-G-A-G-Y-H-A-F-L-D-L-N-N-A-E-R-I-L-Q-E-R-I-E-E-Y-S-K-L-K-T-S-L-E-E-N-I-E-K-L-A-E-R-A-A-Q-I-R-Q-A-L-E-R-L-G-I-R"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-S-Q-E-I-R-A-I-V-R-I-G-D-T-D-L-D-G-N-K-Q-V-A-Y-A-L-A-K-I-R-G-I-G-I-A-S-A-Y-A-I-C-W-K-L-G-I-D-P-H-A-I-L-G-A-L-P-E-D-Q-I-N-K-L-D-W-A-V-R-N-L-H-E-L-A-P-A-W-F-L-N-R-R-K-D-P-E-T-G-R-D-L-H-L-I-G-S-E-L-V-L-A-A-K-R-D-V-D-L-M-K-K-L-K-S-W-K-G-V-R-H-S-L-G-L-K-V-R-G-Q-R-T-V-T-T-G-R-F-G-A-T-A-G-V-T-K-K-K-A-A-A-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-G-G-L-K-K-P-K-K-K-Y-L-A-G-K-P-K-K-I-W-N-K-Q-L-L-L-E-E-L-Q-L-M-G-E-Y-G-L-R-N-K-K-E-L-W-L-A-R-A-R-L-K-W-I-T-R-R-A-R-S-L-L-S-M-T-A-E-E-R-A-P-L-E-M-P-F-K-E-K-L-Y-K-M-G-F-I-E-D-P-N-V-Q-L-D-R-I-L-S-L-D-V-R-A-I-L-E-R-R-L-Q-T-I-V-Y-R-M-G-L-A-K-S-I-H-H-A-R-Q-L-I-V-H-G-H-V-A-V-A-G-R-R-V-T-S-P-G-F-L-V-P-R-E-L-E-D-K-I-S-L-I-Q"} +{"text": "### FUNCTION Involved in ribosome biogenesis ### SEQUENCE -M-K-S-L-L-R-R-C-V-N-C-G-E-Y-T-L-S-K-D-K-C-P-R-C-G-G-A-V-R-V-P-H-P-P-K-F-S-P-E-D-K-Y-Q-K-Y-R-I-L-Q-K-L-L-M-G-K-L-P-I-R-D-E-T-K-E-R-L-L-R-D-L-T-S"} +{"text": "### FUNCTION Broad-specificity nucleoside monophosphate kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-F-D-A-R-R-P-K-A-L-I-T-G-T-P-G-V-G-K-T-T-H-C-R-K-L-A-A-F-L-N-T-K-C-I-S-V-G-E-L-L-A-G-T-P-Y-V-T-Y-I-P-E-L-D-T-Y-E-I-V-D-L-D-G-A-V-K-R-V-H-S-V-V-E-P-G-H-I-I-D-T-H-V-V-E-L-V-P-D-P-E-V-V-I-V-L-R-K-A-P-D-V-L-F-A-E-L-K-R-R-G-W-P-L-K-K-I-L-D-N-V-W-A-E-I-L-D-V-V-L-I-K-A-R-E-R-W-G-E-V-A-Q-I-D-V-T-R-R-R-P-E-E-T-F-E-L-L-K-K-C-V-A-G-G-R-C-H-S-D-V-V-D-W-L-G-Y-S-E-E-S-G-F-L-E-F-I-E-R-L-S-R-S-E-S-F"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-L-A-S-R-R-K-V-R-I-R-L-Y-G-T-N-P-A-D-V-E-Q-V-A-R-E-I-V-D-L-A-K-K-M-G-V-Q-V-R-G-P-I-P-L-P-T-R-R-L-I-V-T-V-R-R-A-P-S-G-Q-G-Y-H-T-F-D-H-W-E-M-R-I-S-K-R-L-I-D-I-E-A-S-E-R-V-L-R-R-L-M-T-I-R-V-P-D-T-V-K-I-E-L-Q-L-I"} +{"text": "### FUNCTION Involved in protein export The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex ### SEQUENCE -M-A-R-R-R-K-Y-E-G-L-N-P-F-V-A-A-G-L-I-K-F-S-E-E-G-E-L-E-K-I-K-L-T-P-R-A-A-V-V-I-S-L-A-I-I-G-L-L-I-A-I-N-L-L-L-P-P-L"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-R-V-V-Y-S-V-E-E-V-E-I-P-K-G-V-S-V-S-I-E-R-T-G-P-F-D-Y-I-V-K-V-K-G-P-L-G-E-V-T-K-E-F-K-N-T-P-V-V-M-S-L-Q-D-G-K-I-V-M-E-V-F-K-A-R-K-R-E-Y-A-I-L-G-T-Y-K-G-I-L-K-N-M-F-L-G-V-T-R-G-W-R-Y-K-L-K-V-I-Y-T-H-F-P-M-L-V-K-V-Q-G-N-Q-L-V-I-E-N-F-L-G-R-K-S-K-I-T-L-N-I-P-K-G-V-K-V-E-V-K-G-K-E-D-I-V-I-E-G-I-D-R-E-L-V-S-T-F-A-A-A-V-Q-A-A-T-E-L-H-G-D-E-R-P-S-P-H-G-R-E-G-G-L-G-V-V-D-G-I-Y-V-V-G-Y-E-H-I-K-S"} +{"text": "### FUNCTION Endonuclease that removes tRNA introns Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp ### SEQUENCE -M-I-G-Y-L-R-G-L-A-V-I-V-E-D-V-E-F-A-R-R-L-Y-K-E-G-F-Y-G-R-F-L-G-Y-D-K-V-K-R-D-E-V-E-K-I-N-A-P-L-I-L-G-L-Y-E-A-L-Y-L-A-E-K-G-R-L-K-V-M-G-E-D-G-R-E-V-A-P-E-E-L-A-A-L-G-R-E-R-M-R-N-F-D-E-I-Y-K-I-Y-K-Y-F-R-D-L-G-Y-V-V-K-S-G-L-K-F-G-A-L-F-S-V-Y-E-K-G-P-G-I-D-H-A-P-M-V-V-V-F-L-E-P-D-K-G-I-S-A-T-D-I-T-R-G-G-R-L-S-H-S-V-R-K-T-W-T-L-A-T-V-L-R-Q-T-G-E-V-V-L-L-G-F-G-W-A-R-L"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-A-T-E-Q-T-I-L-V-G-K-K-P-T-T-N-Y-V-I-A-T-V-M-A-F-N-A-G-V-K-K-V-V-L-K-A-R-G-A-A-I-S-K-A-V-S-T-A-V-M-V-R-D-R-F-L-P-G-K-V-Q-I-K-D-I-K-L-L-S-D-K-V-Q-G-Q-G-G-R-E-R-T-V-A-A-I-E-V-V-L-E-M-A"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-A-Q-I-P-P-S-L-Q-D-L-V-N-R-F-N-Q-A-Q-A-Q-L-Q-N-V-L-L-R-K-Q-Q-Y-E-A-E-L-K-E-V-E-K-A-I-S-E-I-E-R-L-P-Q-D-A-K-I-F-K-N-V-G-N-F-L-V-P-Q-S-R-D-V-A-L-Q-E-L-R-D-R-K-E-L-L-E-L-H-V-K-T-L-T-R-Q-E-S-M-L-R-E-Q-L-D-K-L-R-E-E-I-N-K-E-L-A-K-L-K-G-G-A-T-E-A-A-K-G-G-G"} +{"text": "### FUNCTION Specifically catalyzes the N1-methylation of pseudouridine at position 54 in tRNAs ### SEQUENCE -M-K-N-R-F-D-V-L-V-D-F-V-I-E-S-I-T-G-G-V-R-E-V-Y-V-M-L-C-D-G-S-T-Y-L-I-T-S-L-P-S-Q-R-A-R-A-V-A-R-W-L-L-S-R-Q-P-F-K-T-S-L-Q-A-I-I-A-K-Y-R-S-V-Y-Y-L-H-E-R-G-R-D-I-S-E-A-R-L-D-G-N-G-L-Y-I-F-G-D-H-D-G-L-S-R-E-D-E-E-L-L-A-K-H-A-E-W-I-S-L-G-S-T-P-Y-M-S-W-H-A-A-A-Y-L-A-Y-L-L-K-R-Q-V"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-S-S-K-G-P-S-Y-R-I-E-N-I-V-A-T-V-N-L-G-V-E-L-D-L-E-Q-L-A-E-R-L-T-M-A-E-Y-N-P-D-Q-F-P-G-L-I-L-R-L-T-K-P-R-I-S-A-L-I-F-R-T-G-K-M-V-C-T-G-A-K-N-E-E-D-L-K-N-A-V-R-A-L-V-K-L-L-K-D-H-G-A-D-V-P-F-D-P-E-V-Q-I-Q-N-I-V-A-S-G-N-L-H-A-E-V-D-L-E-Q-A-V-L-M-L-E-N-A-M-Y-E-P-E-Q-F-P-G-L-I-Y-R-M-S-S-P-R-V-V-I-L-I-F-G-S-G-K-I-V-C-T-G-A-K-S-E-K-D-V-A-T-A-V-Q-K-L-Y-N-Q-L-K-E-L-G-V-L-Y-V-E-E-G-G-E-E-L-E-E-F-E-E-E-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-L-D-I-L-S-N-A-L-I-Q-I-K-N-A-E-I-V-G-K-K-Q-A-V-I-W-P-V-N-K-L-T-Y-Y-T-L-R-V-L-Q-R-Y-G-Y-V-G-E-I-E-Y-I-D-D-G-K-G-G-K-Y-I-V-Q-L-L-G-K-I-N-D-I-G-P-I-R-P-R-Y-P-V-K-Y-R-E-I-V-Q-W-E-Q-K-F-L-P-A-R-Q-I-G-I-L-I-I-S-T-S-Q-G-V-M-S-H-I-E-A-K-E-R-K-I-G-G-V-L-L-A-Y-V-Y"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-P-S-T-K-P-P-K-E-R-P-Y-G-K-S-K-I-R-C-L-R-C-G-T-R-E-A-V-I-R-K-Y-G-L-Y-L-C-R-R-C-F-R-E-V-A-P-Q-L-G-F-K-K-Y-Y"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-K-I-R-G-R-A-L-V-Y-G-D-K-I-D-T-D-V-I-I-P-A-K-Y-L-V-Y-T-D-P-A-L-L-G-Q-H-A-M-E-P-L-D-P-E-F-P-K-K-A-K-G-A-V-L-V-A-G-R-A-F-G-M-G-S-S-R-E-Q-A-A-L-A-L-K-G-A-G-V-L-A-V-V-A-E-S-F-A-R-I-F-F-R-N-A-I-N-V-G-L-P-V-L-Q-A-P-G-I-R-E-K-V-K-D-G-D-E-V-E-L-D-V-E-G-G-I-V-R-N-I-T-T-G-E-V-I-V-G-K-P-L-R-G-L-P-L-E-I-L-K-A-G-G-L-L-N-Y-L-K-N-S-R"} +{"text": "### FUNCTION Probable zinc metalloprotease whose natural substrate is unknown ### SEQUENCE -M-R-P-R-I-T-V-V-A-P-S-R-I-K-P-L-E-I-P-E-F-T-T-I-W-Q-F-K-D-I-D-I-S-H-F-L-D-L-A-R-G-Q-C-R-A-D-K-V-V-E-A-L-S-N-G-V-K-S-P-T-V-Y-V-L-D-C-D-G-Y-Y-P-G-L-N-F-V-F-G-L-A-V-P-V-L-K-T-A-V-V-F-T-A-R-L-V-G-P-R-F-E-E-R-L-V-K-E-I-T-H-E-A-G-H-L-Y-G-L-A-H-C-A-N-P-S-C-V-M-Y-F-S-N-S-L-L-D-T-D-R-K-S-P-Y-F-C-P-K-C-R-E-N-L-A-R-I-L"} +{"text": "### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-I-K-R-I-V-V-T-E-K-A-L-R-L-A-E-K-E-N-K-I-T-L-I-V-D-R-G-A-T-K-K-Q-I-A-E-E-V-E-R-L-Y-N-V-K-V-E-K-V-N-T-L-I-T-P-R-G-E-K-K-A-Y-V-K-L-T-K-E-H-N-A-M-D-L-L-S-K-L-G-V-L"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-P-R-H-Q-S-Y-S-L-S-D-E-D-I-I-E-L-V-F-R-N-Y-G-V-K-I-T-P-E-Q-I-A-R-A-Y-A-P-E-Q-R-M-S-W-K-K-S-V-E-V-A-R-F-I-K-G-M-T-L-K-Q-A-K-T-W-L-E-D-V-V-K-L-K-R-P-V-P-I-K-T-F-K-K-K-Q-A-H-H-A-T-P-W-E-G-W-P-V-A-K-W-P-V-K-V-A-R-R-F-L-Q-V-L-E-N-L-E-N-N-A-R-F-R-G-L-D-V-D-R-V-V-I-V-H-A-A-A-H-K-G-F-K-I-P-N-I-M-P-R-A-F-G-R-A-T-R-F-D-E-Q-T-V-N-V-E-L-V-A-V-E-L-P-K-E-V-L-P-K-R-Y-K-L-N-L-V-K-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-V-K-N-I-G-I-P-H-V-L-P-P-A-S-V-C-D-D-P-L-C-P-W-H-G-H-L-K-V-R-L-K-L-L-E-V-T-V-E-K-V-R-M-H-K-A-A-V-V-I-H-E-W-L-H-Y-I-R-K-Y-N-R-Y-E-R-R-R-K-R-M-R-V-R-V-P-E-C-I-E-V-K-P-G-D-K-V-I-I-A-E-T-R-P-L-S-K-T-I-A-W-V-V-I-G-K-K-E-D-V-V-E-W-K-A-K-H-E-T-L-Q-A"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-S-K-E-Q-E-A-Q-K-G-K-Q-G-W-I-T-P-T-V-I-P-P-E-E-W-A-T-F-R-Y-R-G-K-T-L-E-E-L-L-N-M-S-M-D-E-F-I-K-L-L-P-A-R-Q-R-R-S-L-K-R-G-L-K-P-E-H-R-K-L-L-E-K-I-R-K-A-K-R-L-A-A-Q-G-K-K-V-V-I-R-T-H-C-R-D-M-I-I-L-P-E-M-V-G-L-T-I-H-V-Y-N-G-I-T-Y-I-P-V-F-I-S-P-W-H-I-G-H-Y-L-G-E-F-A-L-T-T-K-I-V-Q-H-G-E-P-G-L-K-A-T-R-S-S-L-H-I-A-A-K"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently ### SEQUENCE -M-P-C-G-K-P-G-D-Y-K-Y-G-E-H-T-A-D-V-L-I-Q-A-Y-G-C-T-L-E-E-A-F-K-N-A-A-L-A-L-A-D-L-T-Y-Y-S-S-R-V-E-P-K-E-S-R-E-V-A-V-E-Y-E-D-L-E-G-L-L-F-R-W-I-D-E-L-L-Y-L-F-D-A-E-K-F-A-L-S-R-R-I-E-V-K-L-E-K-G-N-G-Y-A-I-R-A-L-L-Y-G-E-K-Y-D-I-N-K-H-G-F-T-G-L-I-V-K-A-M-T-Y-H-M-M-E-I-K-K-V-E-D-Y-W-L-V-Q-Y-V-V-D-I"} +{"text": "### FUNCTION A probable chromatin protein, binds double-strand DNA without sequence specificity Constrains negative DNA supercoils ### SEQUENCE -M-A-E-E-I-L-N-R-E-Y-E-V-E-Y-E-G-R-K-Y-F-L-R-P-V-K-A-W-V-L-Q-P-P-G-K-P-G-V-V-V-A-L-F-K-L-P-N-G-K-S-I-R-K-V-I-M-R-L-P-P"} +{"text": "### FUNCTION eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA ### SEQUENCE -M-D-S-E-Y-A-A-L-L-E-R-A-Y-K-L-V-A-P-K-A-Q-R-R-A-E-I-P-K-I-E-V-E-N-M-P-R-K-T-I-I-P-N-F-G-Q-I-A-K-R-L-N-R-D-V-Y-F-M-A-K-F-F-Q-K-E-L-A-V-P-G-T-L-E-G-D-V-F-T-L-H-G-E-K-S-P-K-V-V-E-A-V-Y-D-R-F-I-R-Y-Y-V-V-C-P-V-C-N-S-I-D-T-E-L-R-K-E-G-R-I-F-I-M-R-C-L-A-C-G-A-S-T-P-V-R-P-L"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-A-R-L-R-I-I-N-F-Y-R-S-A-Y-C-S-A-M-S-E-F-R-L-P-G-E-G-E-I-L-G-K-V-I-E-M-L-G-D-G-R-F-K-V-I-C-A-D-G-Q-I-R-V-A-R-L-P-G-R-L-R-R-R-L-W-L-K-A-G-D-Y-V-I-V-A-L-W-D-F-D-R-E-K-G-D-I-V-H-K-Y-E-K-R-D-V-E-E-L-K-R-R-G-F-A-E-A-I-E-A-L-D-S-Y-A"} +{"text": "### FUNCTION Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein and RNA polymerase recruitment Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes ### SEQUENCE -M-K-D-V-Y-L-Y-I-V-E-K-S-V-A-W-E-F-D-S-P-E-Y-G-R-L-A-R-K-V-A-E-M-L-Y-E-R-K-E-D-L-T-D-D-R-I-A-I-L-L-N-I-S-T-A-E-T-R-R-I-L-Q-Y-L-M-R-L-N-L-V-G-V-K-K-R-T-T-E-D-Y-R-I-E-Y-T-W-Y-V-D-D-E-I-I-K-Q-A-I-G-G-R-A-R-T-A-R-E-K-I-S-M-L-I-R-A-L-T-E-G-S-Y-Y-I-C-P-N-C-H-M-R-Y-S-L-D-E-A-V-N-K-G-G-V-C-P-V-C-G-A-E-L-E-Y-V-E-S-L-E-E-I-N-K-L-T-K-V-L-Q-K-L-E-K-L"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-D-V-K-M-T-I-A-I-R-G-D-L-K-I-S-C-G-K-A-A-A-Q-A-G-H-A-A-V-E-C-V-L-A-A-M-G-D-A-K-W-R-K-W-L-D-Q-W-L-E-E-G-Q-K-K-I-V-L-T-A-D-D-A-A-H-L-Y-Q-L-H-E-R-A-K-S-L-G-L-P-T-A-V-V-I-D-A-G-L-T-E-L-P-P-G-T-P-T-A-I-C-V-G-P-A-P-D-E-L-V-D-K-V-T-G-S-L-K-L-Y-K"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-S-A-E-V-A-L-V-Y-R-V-L-P-D-S-A-E-V-N-I-E-K-L-K-N-D-V-I-N-K-L-A-P-K-Y-K-V-D-K-V-E-V-E-E-I-G-F-G-I-K-A-L-R-L-Y-I-R-M-P-E-S-D-E-Y-S-S-D-E-I-E-E-L-L-R-S-V-E-G-V-G-G-Y-E-L-E-Y-F-S-R-L-S-F"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-N-V-V-K-R-P-L-D-I-S-Q-L-P-D-A-G-E-V-I-V-D-A-E-G-H-V-A-G-R-L-A-T-Y-I-A-K-A-L-L-E-R-P-N-L-R-I-V-V-V-N-A-E-K-L-V-I-T-G-D-E-K-M-V-I-E-W-F-K-R-K-I-S-E-W-R-T-H-Y-N-P-E-K-A-G-P-K-V-P-R-R-P-D-R-V-F-K-R-I-V-R-G-M-L-P-K-K-S-E-T-G-R-S-A-L-K-R-L-R-V-Y-M-S-I-P-I-E-I-M-Q-R-K-R-L-V-L-Y-E-V-P-E-A-K-L-R-L-R-P-L-L-Q-Y-T-T-L-E-E-V-W-R-S-I-D-P-E-A-W-E-K-W-R-R-A-V-E-V-W-G-K-K-L-K-Q-V-A-S-G"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-G-K-K-S-P-Y-G-L-F-A-G-G-K-L-K-R-K-R-Q-K-F-R-W-N-D-V-T-Y-K-R-K-M-L-G-L-V-E-K-Y-D-P-L-E-G-A-P-M-A-R-G-I-V-L-E-K-V-G-V-E-A-R-K-P-N-A-A-V-R-K-C-V-R-V-Q-L-V-K-N-G-K-V-V-T-A-F-V-P-L-D-G-S-L-N-Y-I-N-E-H-D-E-V-V-I-E-R-I-G-G-P-E-G-R-S-L-G-D-I-P-G-V-R-F-K-V-I-K-V-N-G-V-S-L-W-A-I-W-R-G-K-K-Q-K-P-T-R"} +{"text": "### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates ### SEQUENCE -M-S-R-I-S-L-G-V-K-E-V-T-V-I-P-R-E-E-A-K-E-L-L-K-R-M-K-L-R-P-W-Q-L-P-W-I-R-A-S-D-P-L-A-Q-K-A-G-A-K-P-G-D-V-L-K-I-V-R-E-S-P-T-A-G-E-A-V-V-Y-R-L-V-V-P-G"} +{"text": "### FUNCTION Catalyzes the formation of CDP-2,3-bis- and CTP This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-D-L-T-V-F-F-L-L-I-W-P-P-Y-V-A-N-G-S-A-V-F-A-S-R-L-K-W-R-H-P-V-D-F-G-R-N-F-I-D-G-R-R-I-F-G-D-G-K-T-Y-E-G-V-A-I-G-I-A-T-G-T-V-L-G-Y-F-P-N-L-V-Y-H-V-I-G-V-F-D-A-F-V-L-S-A-S-A-V-L-G-D-L-I-G-A-F-I-K-R-R-L-C-M-P-R-G-H-P-A-F-P-L-D-Q-L-D-F-L-L-T-A-F-L-V-Y-S-L-F-R-E-I-P-V-V-Y-V-L-A-A-V-V-I-T-P-V-I-H-R-A-T-N-Y-V-A-Y-L-L-K-L-K-K-E-P-W"} +{"text": "### FUNCTION Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7 ### SEQUENCE -M-S-W-P-Y-A-T-P-G-I-P-D-E-E-F-I-R-A-E-G-V-P-M-T-K-A-E-I-R-A-L-A-L-S-K-L-R-L-I-K-G-G-T-L-V-D-V-G-C-G-T-G-T-I-S-V-E-A-A-L-I-M-G-E-G-S-K-V-Y-A-I-D-K-D-P-L-A-V-E-I-T-K-K-N-A-A-K-F-G-V-G-D-R-L-I-V-A-E-G-D-A-L-E-L-L-P-K-L-P-R-S-N-R-Y-F-L-G-G-G-G-R-E-L-P-M-L-F-Q-T-A-L-E-L-A-G-T-G-G-V-I-V-A-D-V-I-T-L-E-S-L-R-L-A-L-D-F-L-E-N-A-G-V-K-Y-E-I-A-Q-V-Y-I-A-R-G-R-R-L-G-G-Y-T-I-L-S-P-L-N-P-V-Y-I-I-T-A-Y-A"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-Y-V-V-V-A-Y-D-I-T-E-D-E-V-R-N-K-V-A-D-A-L-K-A-Y-G-L-E-R-I-Q-R-S-V-F-V-G-R-I-N-P-A-L-L-K-D-L-V-E-R-L-K-R-I-T-K-G-A-N-A-D-I-T-I-F-K-V-D-R-R-A-I-D-T-A-I-R-I-G-P-P-P-P-A-R-K-N-V-D-L-Y"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-S-E-V-I-S-I-R-V-R-R-G-L-K-K-E-L-E-E-L-G-I-N-Y-A-E-A-V-R-K-F-L-E-E-L-V-A-R-E-R-R-R-R-A-L-E-R-A-R-A-L-R-E-E-L-R-K-K-G-A-F-P-P-S-A-E-L-I-R-E-D-R-D-E-A-S-R"} +{"text": "### FUNCTION CRISPR Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-I-W-L-A-V-Y-D-I-E-D-D-G-E-R-A-K-A-S-A-I-L-Q-A-W-G-F-V-R-V-Q-R-S-F-Y-V-G-R-M-P-R-G-K-A-A-D-L-L-K-I-L-Q-R-H-V-K-S-G-H-I-A-L-I-P-I-T-D-E-L-L-A-K-A-L-E-L-G-R-P-P-Y-A-P-L-K-P-P-K-Y-A-Q-I-Y-V-V"} +{"text": "### FUNCTION FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters ### SEQUENCE -M-A-F-N-G-T-W-Q-V-Y-S-Q-E-N-Y-E-D-F-L-K-A-I-A-L-P-D-D-I-I-K-A-A-K-D-V-K-P-V-T-E-I-R-Q-T-G-N-T-F-V-V-T-S-K-T-P-N-K-S-V-T-N-S-F-T-L-G-K-E-A-D-M-T-T-M-D-G-K-K-V-K-C-T-V-N-L-V-D-G-K-L-V-A-K-S-D-K-F-I-H-E-Q-E-I-V-G-N-E-M-V-E-T-I-T-S-G-S-A-T-F-T-R-R-S-K-K-I"} +{"text": "### FUNCTION Contributes to the transparency and refractive index of the lens May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions ### SEQUENCE -R-A-L-G-P-L-I-P-S-R-L-F-D-Q-F-F-G-E-G-L-L-E-Y-D-L-L-P-L-F-S-S-T-I-S-P-Y-Y-R-Q-S-L-F-R-S-V-L-E-S-G-I-S-E-V-R-S-D-R-E-K-F-T-I-M-L-D-V-K-H-F-S-P-E-D-L-S-V-K-I-I-D-D-F-V-E-I-H-G-K-H-S-E-R-Q-D-D-H-G-Y-I-S-R-E-F-H-R-R-Y-R-L-P-S-N-V-D-Q-S-A-I-T-C-S-L-S-S-D-G-M-L-T-F-S-G-P-K-V-Q-A-N-M-D-P-S-H-S-E-R-P-I-P"} +{"text": "### FUNCTION Has no ubiquitin ligase activity on its own The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63' This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome Plays a role in the activation of NF-kappa-B Mediates transcriptional activation of target genes Plays a role in the control of progress through the cell cycle and differentiation Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage ### SEQUENCE -M-A-A-T-T-G-V-K-V-P-R-N-F-R-L-L-E-E-L-E-E-G-Q-K-G-V-G-D-G-T-V-S-W-G-L-E-D-D-E-D-M-T-L-T-R-W-T-G-M-I-I-G-P-P-R-T-I-Y-E-N-R-I-Y-S-L-K-I-E-C-G-P-K-Y-P-E-A-P-P-F-V-R-F-V-T-K-I-N-M-N-G-V-N-S-S-N-G-V-V-D-P-R-A-I-S-V-L-A-K-W-Q-N-S-F-S-I-K-V-V-L-Q-E-L-R-R-L-M-M-S-K-E-N-M-K-L-P-Q-P-P-E-G-Q-C-Y-S-N"} +{"text": "### FUNCTION Antimicrobial peptide ### SEQUENCE -M-K-F-T-A-T-F-L-V-L-S-L-V-V-L-M-A-E-P-G-E-C-F-L-G-A-L-I-K-G-A-I-H-G-G-R-F-I-H-G-M-I-Q-N-H-H-G-Y-D-E-Q-Q-E-L-N-K-R-A-V-D-E"} +{"text": "### FUNCTION Serine protease inhibitor Does not inhibit plasmin, and does not reduce blood loss in the mouse tail vein blood loss model ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-W-E-V-L-T-P-V-S-S-K-D-R-P-K-F-C-E-L-P-A-D-I-G-P-C-D-D-F-T-G-A-F-H-Y-S-P-R-E-H-E-C-I-E-F-I-Y-G-G-C-K-G-N-A-N-N-F-N-T-Q-E-E-C-E-S-T-C-A-A"} +{"text": "### FUNCTION Serine protease inhibitor Does not inhibit plasmin, and does not reduce blood loss in the mouse tail vein blood loss model ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-W-E-V-L-T-P-V-S-S-K-D-R-P-K-F-C-E-L-L-P-D-T-G-S-C-E-D-F-T-G-A-F-H-Y-S-T-R-D-R-E-C-I-E-F-I-Y-G-G-C-G-G-N-A-N-N-F-I-T-K-E-E-C-E-S-T-C-A-A"} +{"text": "### FUNCTION NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone ### SEQUENCE -M-H-P-N-L-V-S-W-L-G-T-L-G-L-L-L-W-A-L-L-C-L-S-A-L-T-E-G-Y-P-V-K-P-E-N-P-G-D-D-A-P-A-E-E-L-A-K-Y-Y-S-A-L-R-H-Y-I-N-L-I-T-R-Q-R-Y-G-K-R-S-S-P-E-I-L-D-T-L-V-S-E-L-L-L-K-E-S-T-D-T-L-P-Q-S-R-Y-D-P-S-L-W"} +{"text": "### FUNCTION TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation TFIIA in a complex with TBP mediates transcriptional activity ### SEQUENCE -M-A-Y-Q-L-Y-R-N-T-T-L-G-N-S-L-Q-E-S-L-D-E-L-I-Q-T-Q-Q-I-T-P-Q-L-A-L-Q-V-L-L-Q-F-D-K-A-I-N-T-A-L-A-N-R-V-R-N-R-V-N-F-K-G-S-L-N-T-Y-R-F-C-D-N-V-W-T-F-V-L-N-D-V-E-F-R-E-V-T-D-L-V-K-V-D-K-V-K-I-V-A-C-D-G-K-N-T-G-N-A-A-E"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-N-G-Q-G-A-S-A-D-P-Q-L-Q-Q-F-I-E-I-E-S-Q-K-Q-R-F-Q-Q-L-V-H-H-M-T-E-V-C-W-D-K-C-M-D-K-P-G-P-K-L-D-S-R-A-E-M-C-F-V-N-C-V-E-R-F-I-D-T-S-Q-F-I-L-N-R-L-E-Q-T-Q-R-S-K-G-S-F-S-E-T-M-T-D"} +{"text": "### FUNCTION In muscle, parvalbumin is thought to be involved in relaxation after contraction It binds two calcium ions ### SEQUENCE -M-A-F-A-G-I-L-K-D-A-E-V-A-A-A-L-E-A-C-K-S-A-G-S-F-D-H-T-K-F-F-K-S-C-G-L-A-G-K-S-S-D-D-V-K-K-A-F-G-I-I-D-Q-D-Q-S-D-F-I-E-E-E-E-L-K-L-F-L-Q-N-F-S-A-S-A-R-A-L-S-D-A-E-T-K-A-F-L-K-A-G-D-S-D-G-D-G-K-I-G-V-D-E-F-A-A-M-V-K-A"} +{"text": "### FUNCTION In muscle, parvalbumin is thought to be involved in relaxation after contraction It binds two calcium ions ### SEQUENCE -M-S-F-A-G-V-L-A-D-A-D-V-K-A-A-L-A-G-C-A-A-A-D-S-F-N-Y-K-T-F-F-K-A-C-G-L-A-A-K-S-H-E-E-V-K-K-A-F-F-V-I-D-Q-D-Q-S-G-F-I-E-E-D-E-L-K-L-F-L-Q-T-F-G-A-G-A-R-E-L-T-A-A-E-T-K-A-F-L-A-A-G-D-E-D-G-D-G-M-I-G-V-D-E-F-V-T-L-V-K-A"} +{"text": "### FUNCTION In muscle, parvalbumin is thought to be involved in relaxation after contraction It binds two calcium ions ### SEQUENCE -M-A-F-A-G-I-L-N-D-A-D-I-T-A-A-L-A-A-C-K-A-E-G-S-F-D-H-K-A-F-F-T-K-V-G-L-A-A-K-S-P-A-D-I-K-K-V-F-E-I-I-D-Q-D-K-S-D-F-V-E-E-D-E-L-K-L-F-L-Q-N-F-S-A-G-A-R-A-L-S-D-A-E-T-K-V-F-L-K-A-G-D-S-D-G-D-G-K-I-G-V-D-E-F-G-A-M-I-K-A"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-G-H-Q-Q-L-Y-W-S-H-P-R-K-F-G-Q-G-S-R-S-C-R-V-C-S-N-R-H-G-L-I-R-K-Y-G-L-N-M-C-R-Q-C-F-R-Q-Y-A-K-D-I-G-F-V-K-L-D"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-D-A-S-R-V-Q-P-I-K-L-A-R-V-T-K-V-L-G-R-T-G-S-Q-G-Q-C-T-Q-V-R-V-E-F-M-D-D-S-N-R-S-I-I-R-N-V-K-G-P-V-R-E-G-D-V-L-T-L-L-E-S-E-R-E-A-R-R-L-R"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-P-P-K-D-S-K-Q-K-K-D-T-S-K-A-K-K-D-K-D-P-V-N-K-S-G-G-K-A-K-K-K-K-W-S-K-G-K-V-R-D-K-L-N-N-L-V-L-F-D-K-A-T-Y-D-K-L-Y-K-E-V-P-N-Y-K-L-I-T-P-A-V-V-S-E-R-L-K-I-R-G-S-L-A-R-A-A-L-L-E-L-L-S-K-G-M-I-K-L-V-S-K-H-R-A-Q-V-I-Y-T-R-N-T-K-G-T-D-E-G-A-P-E-K-E-A"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-Q-N-D-A-G-E-F-V-D-L-Y-V-P-R-K-C-S-A-S-N-R-I-I-G-A-K-D-H-A-S-I-Q-I-N-I-A-E-V-D-K-V-T-G-R-F-N-G-Q-F-K-T-Y-A-I-C-G-A-I-R-R-M-G-E-A-D-D-S-L-L-R-L-A-K-N-D-S-I-V-S-K-N-I"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-S-L-V-I-P-E-K-F-Q-H-I-L-R-V-L-N-T-N-I-D-G-R-R-K-I-A-F-A-I-T-A-I-K-G-V-G-R-R-Y-A-H-V-V-L-R-K-A-D-I-D-L-S-K-R-A-G-E-L-T-E-D-E-V-E-R-V-V-T-I-M-Q-N-P-R-Q-Y-K-I-P-D-W-F-L-N-R-Q-K-D-V-K-D-G-K-Y-S-Q-V-L-A-N-G-L-D-N-K-L-R-E-D-L-E-R-L-K-K-I-R-A-H-R-G-L-R-H-F-W-G-L-R-V-R-G-Q-H-T-K-T-T-G-R-R-G-R-T-V-G-V-S-K-K-K"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-G-R-V-R-T-K-T-V-K-K-A-A-R-V-I-I-E-K-Y-Y-T-R-L-G-N-D-F-H-T-N-K-R-V-C-E-E-I-A-I-I-P-S-K-K-L-R-N-K-I-A-G-Y-V-T-H-L-M-K-R-I-Q-R-G-P-V-R-G-I-S-I-K-L-Q-E-E-E-R-E-R-R-D-N-Y-V-P-E-V-S-A-L-D-Q-E-I-I-E-V-D-P-D-T-K-E-M-L-K-L-L-D-F-G-S-L-S-N-L-Q-V-T-Q-P-T-V-G-M-N-F-K-T-P-R-G-V"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-P-A-K-G-P-L-Q-S-V-Q-V-F-G-R-K-K-T-A-T-A-V-A-H-C-K-R-G-N-G-L-I-K-V-N-G-R-P-L-E-T-I-E-P-A-T-L-Q-Y-K-L-L-E-P-V-L-L-L-G-K-E-R-F-A-G-V-D-I-R-V-R-V-K-G-G-G-H-V-A-Q-V-Y-A-I-R-Q-S-I-S-K-A-L-V-A-Y-Y-Q-K-Y-V-D-E-A-S-K-K-E-I-K-D-I-L-I-Q-Y-D-R-T-L-L-V-A-D-P-R-R-C-E-S-K-K-F-G-G-P-G-A-R-A-R-Y-Q-K-S-Y-R"} +{"text": "### FUNCTION Component of the 40S ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-L-M-P-K-K-N-R-I-A-I-Y-E-L-L-F-K-E-G-V-M-V-A-K-K-D-V-H-L-A-K-H-P-E-L-A-D-K-N-V-P-N-L-H-V-M-K-A-M-Q-S-L-K-S-C-G-Y-V-K-E-Q-F-A-W-R-H-F-Y-W-Y-L-T-N-E-G-I-Q-Y-L-R-D-F-L-H-L-P-P-E-I-V-P-A-T-L-R-R-Q-T-R-P-E-T-A-R-P-R-P-K-G-L-E-G-E-R-P-A-R-L-A-R-G-E-G-D-R-D-A-Y-R-R-S-A-A-P-P-G-A-D-K-K-A-E-A-G-A-G-A-A-T-E-F-Q-F-R-G-G-F-G-R-G-R-G-Q-Q-P-Q"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-R-A-K-W-R-K-K-R-M-R-G-L-K-R-K-R-R-K-M-R-Q-R-S-K"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-K-R-T-K-K-V-G-I-V-G-K-Y-G-T-R-Y-G-A-S-L-R-K-M-V-K-K-I-E-I-S-Q-H-A-K-Y-T-C-S-F-C-G-K-T-K-M-K-R-R-A-V-G-I-W-H-C-G-S-C-M-K-T-V-A-G-G-A-W-T-Y-N-T-T-S-A-V-T-V-K-S-A-I-K-R-L-K-E-M-K-D-Q"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-T-K-G-T-S-S-F-G-K-R-R-N-K-T-H-T-L-C-R-R-C-G-S-K-A-Y-H-L-Q-K-S-T-C-G-K-C-G-Y-P-A-K-R-K-R-K-Y-N-W-S-A-K-A-K-R-R-S-T-T-G-T-G-R-M-R-H-M-K-V-V-F-R-R-F-R-N-G-F-R-E-G-T-V-P-K-P-R-R-A-A-V-A-A-S-S-S-S"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-I-R-Y-P-M-A-V-G-L-K-K-G-H-P-V-T-K-N-V-T-K-P-K-H-S-R-R-G-G-R-L-T-K-H-S-K-F-V-R-D-M-I-R-E-V-C-G-F-A-P-Y-E-R-R-A-M-E-L-L-K-V-S-K-D-K-R-A-L-K-F-I-K-K-R-V-G-T-H-I-R-A-K-R-K-R-E-E-L-S-N-I-L-A-A-M-R-K-A-A-A-K-K-E"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-P-G-R-L-W-C-K-A-I-F-A-G-Y-K-R-G-L-R-N-Q-R-E-H-T-A-L-L-K-V-E-G-V-Y-S-R-N-E-V-D-F-Y-L-G-K-R-C-A-Y-V-Y-K-A-K-K-T-T-V-T-P-G-G-K-P-N-K-T-R-V-I-W-G-K-V-T-R-A-H-G-N-S-G-M-V-R-A-K-F-T-S-N-L-P-P-K-A-I-G-H-R-I-R-V-M-L-Y-P-S-R-V"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-K-I-K-A-R-D-L-R-G-K-K-K-E-E-L-L-K-H-V-D-D-L-K-V-E-L-S-Q-L-R-V-A-K-V-T-G-G-A-A-S-K-L-S-K-I-R-V-V-R-K-S-I-A-R-V-L-T-V-I-N-Q-T-Q-K-E-N-L-R-K-F-Y-K-G-K-K-Y-K-P-L-D-L-R-P-R-K-T-R-A-I-R-R-Q-L-T-K-H-E-Q-G-L-M-T-K-K-M-Q-R-R-S-R-L-Y-S-M-R-K-F-A-V-K-A"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-V-Q-R-L-T-Y-R-R-T-V-S-Y-N-T-T-S-N-K-T-R-L-S-R-T-P-G-N-R-I-V-Y-L-Y-T-K-K-T-G-K-A-P-K-S-A-C-G-I-C-P-G-R-L-R-G-I-R-A-V-R-P-Q-V-L-M-R-L-S-K-T-K-K-H-V-S-R-A-Y-G-G-S-M-C-A-K-C-V-R-D-R-I-K-R-A-F-L-I-E-E-Q-K-I-V-V-K-V-L-K-A-Q-A-Q-S-Q-K-A-K"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-A-L-R-P-L-T-K-P-K-I-V-K-K-R-T-K-K-F-I-R-H-Q-S-D-R-Y-V-K-I-R-R-N-W-R-K-P-R-G-I-D-N-R-V-R-S-G-F-K-G-Q-M-L-M-P-N-I-G-Y-G-S-N-K-K-T-K-H-M-L-P-S-G-F-K-K-F-L-V-H-N-V-K-E-L-E-V-L-L-M-S-N-K-S-Y-C-A-E-I-A-H-N-V-S-S-K-N-R-K-V-I-V-E-R-A-A-Q-L-A-I-K-V-T-N-P-N-A-R-L-R-S-E-E-N-E"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-P-L-K-K-G-G-E-K-K-K-G-R-S-A-I-N-E-V-V-T-R-E-Y-T-I-N-V-H-K-R-I-H-G-I-S-F-K-K-R-A-P-R-A-I-K-E-I-R-K-F-A-M-K-E-M-G-T-P-D-V-R-I-D-T-R-L-N-K-A-V-W-A-K-G-V-R-N-V-P-Y-R-M-R-V-R-L-S-R-K-R-N-E-D-E-D-S-P-N-K-L-Y-T-L-V-T-Y-V-P-V-T-T-Y-K-G-L-Q-T-V-N-V-D-E-N"} +{"text": "### FUNCTION Component of the large ribosomal subunit ### SEQUENCE -M-G-K-F-M-K-P-G-K-V-V-M-V-L-A-G-R-Y-A-G-R-K-A-V-I-V-K-N-I-D-D-G-T-A-D-R-P-Y-S-H-A-L-V-S-G-I-D-R-Y-P-R-K-V-T-A-T-M-G-K-K-K-V-A-K-R-S-K-I-K-A-F-V-K-V-F-N-Y-N-H-L-M-P-T-R-Y-S-V-D-I-P-L-D-K-T-I-V-N-K-D-V-F-R-D-P-A-L-K-R-K-A-R-R-E-A-K-V-K-F-E-E-R-Y-K-T-G-K-N-K-W-F-F-Q-K-L-R-F"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-K-V-E-L-C-S-F-S-G-Y-K-I-Y-P-G-H-G-P-V-Y-A-R-I-D-G-K-V-F-Q-F-L-N-A-K-C-E-S-A-F-L-T-K-R-N-P-R-Q-I-N-W-T-V-L-Y-R-R-K-H-K-K-G-Q-S-E-E-V-T-K-K-R-T-R-R-A-V-K-F-Q-R-A-I-T-G-A-S-L-A-E-I-L-A-K-R-N-Q-K-P-E-V-R-K-A-Q-R-E-Q-A-I-R-A-A-K-E-A-K-K-A-K-Q-A-T-K-K-V-S-T-Q-S-T-K-A-P-A-K-A-A-P-K-Q-K-I-A-K-P-M-K-V-S-A-P-R-V-G-G-K-R"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-S-K-R-G-R-G-G-S-S-G-A-K-F-R-I-S-L-G-L-P-V-G-A-V-I-N-C-A-D-N-T-G-A-K-N-L-Y-I-I-S-V-K-G-I-K-G-R-L-N-R-L-P-A-A-G-V-G-D-M-V-M-A-T-V-K-K-G-K-P-E-L-R-K-K-V-H-P-A-V-V-I-R-Q-R-K-S-Y-R-R-K-D-G-V-F-L-Y-F-E-D-N-A-G-V-I-V-N-N-K-G-E-M-K-G-S-A-I-T-G-P-V-A-K-E-C-A-D-L-W-P-R-I-A-S-N-A-G-S-I-A"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-P-L-K-K-P-A-V-K-G-G-K-K-K-K-Q-V-L-K-F-T-L-D-C-T-H-P-V-E-D-G-I-M-D-A-A-N-F-E-Q-F-L-Q-E-R-I-K-V-N-G-K-A-G-N-L-G-G-G-V-V-S-I-E-R-S-K-S-K-I-T-V-T-S-D-I-P-F-S-K-R-Y-L-K-Y-L-T-K-K-Y-L-K-K-N-N-L-R-D-W-L-R-V-V-A-N-T-K-E-S-Y-E-L-R-Y-F-Q-I-N-Q-D-E-E-E-E-E-D-E-D"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-S-M-L-R-L-Q-K-R-L-A-S-S-V-L-R-C-G-K-K-K-V-W-L-D-P-N-E-T-N-E-I-A-N-A-N-S-R-Q-A-I-R-K-L-V-K-D-G-L-I-I-K-K-P-V-T-V-H-S-R-A-R-C-R-K-N-T-L-A-R-R-K-G-R-H-M-G-I-G-K-R-K-G-T-A-N-A-R-M-P-E-K-L-C-W-M-R-R-M-R-I-L-R-R-L-L-R-R-Y-R-E-S-K-K-I-D-R-H-M-Y-H-S-L-Y-L-R-A-K-G-N-V-F-K-N-K-R-I-L-M-E-H-I-H-K-L-K-A-D-R-A-R-K-K-L-L-S-D-Q-A-E-A-R-R-S-K-T-R-E-A-R-K-R-R-E-E-R-L-Q-A-K-K-E-E-I-I-K-N-L-S-K-E-E-E-G-K-K"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-K-A-S-G-T-L-R-E-Y-K-V-V-G-R-L-L-P-S-A-K-N-P-T-P-P-L-Y-R-M-R-I-F-A-P-N-H-V-V-A-K-S-R-F-W-Y-F-V-S-Q-L-R-K-M-K-K-A-N-G-E-T-V-Y-C-G-L-V-H-E-Q-S-P-L-K-V-K-N-F-G-I-W-L-R-Y-D-S-R-S-G-T-H-N-M-Y-R-E-Y-R-D-L-T-T-S-G-A-V-T-Q-C-Y-R-D-M-G-A-R-H-R-A-R-A-H-A-I-Q-I-M-K-V-Q-V-I-A-A-N-K-C-R-R-A-A-I-K-Q-F-H-D-S-K-I-K-F-P-L-P-H-R-V-L-R-R-Q-H-K-P-R-F-T-T-R-R-P-Q-T-F-F"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-G-V-D-I-R-H-N-K-D-R-K-V-H-R-T-E-P-K-S-Q-D-I-Y-L-R-L-L-V-K-L-Y-R-F-L-A-R-R-S-D-A-P-F-N-K-V-V-L-K-R-L-F-M-S-K-T-N-R-P-P-L-A-L-S-R-L-I-R-K-M-K-L-Q-G-R-E-N-K-I-A-V-V-V-G-T-I-T-D-D-V-R-I-L-N-I-P-K-L-K-V-C-A-L-R-V-T-A-G-A-R-R-R-I-L-K-A-G-G-Q-V-M-T-F-D-Q-L-A-V-T-T-P-K-G-Q-G-T-V-L-L-S-G-P-R-K-A-R-E-V-Y-R-H-F-G-K-A-P-G-T-P-H-S-H-T-K-P-Y-I-R-S-K-G-R-K-F-E-R-A-R-G-R-R-A-S-R-G-Y-K-N"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-A-D-Q-G-E-K-K-E-N-P-M-R-E-L-R-I-R-K-L-C-L-N-I-C-V-G-E-S-G-D-R-L-T-R-A-A-K-V-L-E-Q-L-T-G-Q-T-P-V-F-S-K-A-R-Y-T-V-R-S-F-G-I-R-R-N-E-K-I-A-V-H-C-T-V-R-G-A-K-A-E-E-I-L-E-K-G-L-K-V-R-E-Y-E-L-R-K-N-N-F-S-D-S-G-N-F-G-F-G-I-Q-E-H-I-D-L-G-I-K-Y-D-P-S-I-G-I-Y-G-L-D-F-Y-V-V-L-G-R-P-G-F-S-I-A-D-K-K-R-K-R-G-R-I-G-F-K-H-R-I-R-K-R-E-A-M-R-W-F-Q-Q-K-Y-D-G-V-I-L-P-G-K"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-K-T-I-L-S-T-Q-T-V-D-I-P-D-N-V-D-V-T-L-K-G-R-T-V-S-V-K-G-P-R-G-V-L-R-R-E-F-N-H-I-N-L-E-L-R-L-L-G-K-K-Q-K-K-L-R-V-D-K-W-W-G-N-R-K-E-L-A-T-V-R-T-I-C-S-H-V-Q-N-M-I-K-G-V-T-L-G-F-R-Y-K-M-R-S-V-Y-A-H-F-P-I-N-V-V-I-Q-E-T-G-S-L-V-E-I-R-N-F-L-G-E-K-Y-I-R-R-V-R-M-R-P-G-V-N-C-A-L-S-A-A-Q-K-D-E-L-V-L-E-G-N-D-I-E-L-V-S-N-S-A-A-L-I-Q-Q-A-T-T-V-K-N-K-D-I-R-K-F-L-D-G-I-Y-V-S-E-K-G-T-V-V-E-P-E-S"} +{"text": "### FUNCTION May have role in testicular activity ### SEQUENCE -M-S-D-T-S-V-D-A-S-V-E-K-T-T-K-D-L-K-S-K-D-K-E-L-V-E-E-T-E-N-G-K-D-K-P-A-N-G-N-A-E-N-E-E-N-G-E-D-G-A-D-N-E-E-E-E-E-V-D-E-E-D-E-E-D-E-G-E-G-D-D-D-E-G-D-E-D-D-E-A-D-G-A-T-G-K-R-A-A-E-D-D-D-E-D-D-D-V-D-A-K-K-Q-K-T-D-D-D-D"} +{"text": "### FUNCTION Has antimicrobial activity ### SEQUENCE -M-A-S-L-K-K-S-L-F-L-V-L-F-L-G-L-V-S-L-S-I-C-E-E-E-K-R-E-N-E-D-E-E-E-Q-E-D-D-E-Q-S-E-M-K-R-G-L-W-S-N-I-K-T-A-G-K-E-A-A-K-A-A-L-K-A-A-G-K-A-A-L-G-A-V-T-D-A-V-G-E-Q"} +{"text": "### FUNCTION Has antimicrobial activity ### SEQUENCE -M-A-F-L-K-K-S-L-F-L-V-L-F-L-G-L-V-S-L-S-I-C-E-E-E-K-R-E-N-E-D-E-E-E-Q-E-D-D-E-Q-S-E-M-K-R-G-L-W-S-K-I-K-E-A-G-K-A-A-L-T-A-A-G-K-A-A-L-G-A-V-S-D-A-V-G-E-Q"} +{"text": "### FUNCTION Antimicrobial peptide ### SEQUENCE -M-K-F-T-A-T-F-L-M-M-F-I-F-V-L-M-V-E-P-G-E-C-G-W-G-S-I-F-K-H-G-R-H-A-A-K-H-I-G-H-A-A-V-N-H-Y-L-G-E-Q-Q-D-L-D-K-R-A-V-D-E-D-P-N-V-I-V-F-E"} +{"text": "### FUNCTION Plays an important role in catfish calcium homeostasis ### SEQUENCE -M-S-D-L-Q-K-G-M-A-L-L-I-S-T-F-H-K-Y-S-G-K-E-G-D-K-C-T-L-T-K-G-E-L-K-D-L-L-T-K-E-L-G-G-A-F-G-N-C-S-D-Q-A-T-L-D-K-I-F-K-D-L-D-T-N-A-D-G-V-V-D-F-Q-E-Y-A-T-M-V-A-C-T-T-M-L-C-N-K-S-L-S-K-K"} +{"text": "### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-D-S-N-T-V-S-S-F-Q-D-I-L-L-R-M-S-K-M-Q-L-G-S-S-S-E-D-L-N-G-M-I-T-Q-F-E-S-L-K-L-Y-R-D-S-L-G-E-A-V-M-R-M-G-D-L-H-S-L-Q-N-R-N-G-K-W-R-E-Q-L-G-Q-K-F-E-E-I-R-W-L-I-E-E-V-R-H-R-L-K-T-T-E-N-S-F-E-Q-I-T-F-M-Q-A-L-Q-L-L-F-E-V-E-Q-E-I-R-T-F-S-F-Q-L-I"} +{"text": "### FUNCTION Has low cytotoxic activity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-H-N-T-Q-L-P-F-I-Y-K-T-C-P-E-G-K-N-L-C-F-K-A-T-L-K-K-F-P-L-K-F-P-V-K-R-G-C-A-D-N-C-P-K-N-S-A-L-L-K-Y-V-C-C-S-T-E-K-C-N"} +{"text": "### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-A-A-A-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-K-L-I-P-I-A-S-K-T-C-P-A-G-M-N-L-C-Y-K-M-F-M-M-S-D-L-T-I-P-V-K-R-G-C-I-D-V-C-P-K-N-S-L-L-V-K-Y-V-C-C-N-T-D-R-C-N"} +{"text": "### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-K-L-I-P-I-A-S-K-T-C-T-A-G-K-N-L-C-Y-K-M-F-M-M-S-D-L-T-I-P-V-K-R-G-C-I-D-V-C-P-K-N-S-L-L-V-K-Y-V-C-C-N-T-D-R-C-N"} +{"text": "### FUNCTION Has low cytotoxic activity ### SEQUENCE -M-K-T-L-L-L-T-M-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-H-N-T-Q-L-P-F-I-Y-K-T-C-P-E-G-K-N-L-C-F-K-A-T-L-K-K-F-P-L-K-F-P-V-K-R-G-C-A-D-N-C-P-K-N-S-A-L-L-K-Y-V-C-C-S-S-D-K-C-N"} +{"text": "### FUNCTION Isotocin causes contraction of smooth muscles ### SEQUENCE -M-T-G-A-A-V-S-V-C-L-L-Y-A-L-S-V-C-S-A-C-Y-I-S-N-C-P-I-G-G-K-R-S-I-M-D-A-P-Q-R-K-C-M-S-C-G-P-G-E-Q-G-R-C-F-G-P-S-I-C-C-G-K-D-V-G-C-W-M-G-S-P-E-T-A-H-C-M-E-E-N-Y-L-P-T-P-C-Q-V-G-G-R-P-C-G-S-D-T-V-R-C-A-S-P-G-V-C-C-D-S-E-G-C-S-A-D-Q-S-C-F-A-E-E-E-G-D-N-Q-I-G-Q-S-E-G-S-N-S-A-D-V-I-L-R-L-L-H-L-A-D-H-T-P-P-H-R-V-H-Q"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-R-R-Q-A-S-L-P-A-R-R-R-R-R-V-R-R-T-R-V-V-R-R-R-R-R-V-G-R-R-R-H"} +{"text": "### FUNCTION Contributes to the transparency and refractive index of the lens May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions ### SEQUENCE -M-D-I-A-I-Q-H-P-W-F-K-R-A-L-G-P-F-Y-P-N-R-L-F-D-Q-V-F-G-E-G-M-F-D-Y-D-L-F-P-F-L-S-S-T-V-S-P-Y-Y-R-H-S-L-F-R-G-F-M-D-S-G-I-S-E-V-R-S-D-R-D-R-F-T-I-N-L-D-V-K-H-F-S-P-D-D-L-T-V-K-I-L-D-D-F-V-E-I-H-G-K-H-S-E-R-Q-D-D-H-G-Y-I-S-R-E-F-H-R-R-Y-R-L-P-S-N-L-D-Q-S-S-I-S-C-S-L-S-A-D-G-I-L-T-F-S-G-P-K-M-M-S-G-L-D-S-S-H-S-E-R-P-I-P-V-S-R-E-E-K-P-T-S-A-P-S-S"} +{"text": "### FUNCTION Crystallins are the dominant structural components of the vertebrate eye lens ### SEQUENCE -M-G-K-I-I-F-Y-E-D-R-N-F-Q-G-R-S-Y-E-C-S-N-D-N-P-D-L-Q-P-N-F-N-A-C-N-S-V-R-V-E-N-G-C-W-M-I-Y-E-R-P-N-Y-M-G-H-P-Y-F-L-K-R-G-E-Y-P-D-Y-Q-Q-C-Q-G-L-N-D-S-I-R-S-S-R-L-L-S-Q-N-L-G-I-G-T-N-K-L-R-V-Y-E-R-G-D-S-K-G-E-M-M-E-F-L-E-D-C-P-N-V-Y-D-R-F-C-S-H-E-I-H-S-C-N-V-L-D-G-Y-W-I-F-Y-E-L-P-N-Y-K-G-K-Q-Y-L-L-R-P-G-E-Y-K-R-F-T-D-W-G-S-Q-T-A-K-V-G-S-F-R-R-V-I-D-I-C"} +{"text": "### FUNCTION Crystallins are the dominant structural components of the vertebrate eye lens ### SEQUENCE -M-G-K-I-I-F-Y-E-D-R-N-F-Q-G-R-S-Y-E-C-S-N-D-N-P-D-L-Q-P-N-F-N-A-C-N-S-V-R-V-E-N-G-C-W-M-I-Y-E-R-P-N-Y-M-G-H-Q-Y-F-L-K-R-G-E-Y-P-D-Y-Q-Q-C-Q-G-L-N-D-S-P-Q-S-S-R-L-L-S-Q-N-L-G-I-G-T-N-K-L-R-V-Y-E-R-G-D-S-K-G-E-M-M-E-F-L-E-D-C-P-N-V-Y-D-R-F-C-S-H-E-I-H-S-C-N-V-L-D-G-Y-W-I-F-Y-E-L-P-N-Y-K-G-K-Q-Y-L-L-R-P-G-E-Y-K-R-F-T-D-W-G-S-Q-T-A-K-V-G-S-F-R-R-V-I-G-I-C"} +{"text": "### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-V-H-I-C-R-L-L-V-L-M-G-M-L-L-C-L-S-A-Q-F-A-S-S-Q-H-W-S-H-G-W-Y-P-G-G-K-R-E-I-D-I-Y-D-T-S-E-V-S-G-E-I-K-L-C-E-A-G-K-C-S-Y-L-R-P-Q-G-R-N-I-L-K-T-I-L-L-D-A-L-I-R-D-F-Q-K-R-K"} +{"text": "### FUNCTION Small multifunctional phosphoprotein involved in virion morphogenesis, egress and counteracting host innate immunity ### SEQUENCE -M-C-L-S-C-Q-F-W-C-L-E-C-Q-E-S-G-V-G-C-R-C-V-D-C-C-S-C-L-Q-C-A-A-G-C-Q-G-A-P-K-R-S-Q-P-E-A-G-V-A-S-A-A-V-T-I-Q-P-S-G-A-L-N-N-A-P-R-E-P-S-A-P-P-L-S-Q-T-L-S-P-R-Q-V-L-A-R-Y-Q-M"} +{"text": "### FUNCTION In muscle, parvalbumin is thought to be involved in relaxation after contraction It binds two calcium ions ### SEQUENCE -M-A-C-A-H-L-C-K-E-A-D-I-K-T-A-L-E-A-C-K-A-A-D-T-F-S-F-K-T-F-F-H-T-I-G-F-A-S-K-S-A-D-D-V-K-K-A-F-K-V-I-D-Q-D-A-S-G-F-I-E-V-E-E-L-K-L-F-L-Q-N-F-C-P-K-A-R-E-L-T-D-A-E-T-K-A-F-L-K-A-G-D-A-D-G-D-G-M-I-G-I-D-E-F-A-V-L-V-K-Q"} +{"text": "### FUNCTION Contributes to the transparency and refractive index of the lens May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions ### SEQUENCE -R-A-L-G-P-L-F-P-S-R-L-F-D-Q-Y-L-G-E-G-L-F-D-Y-D-L-L-P-F-F-S-S-T-I-S-P-Y-Y-R-H-S-L-F-R-T-V-L-E-S-G-I-S-E-V-R-S-D-R-D-K-F-T-I-L-L-D-V-K-H-F-S-P-E-D-L-S-V-K-I-M-D-D-F-V-E-I-H-G-K-H-N-E-R-Q-D-D-H-G-Y-I-S-R-E-F-H-R-R-Y-R-L-P-S-N-V-D-Q-S-A-I-T-C-S-L-S-A-D-G-M-L-T-F-S-G-P-K-V-Q-S-N-M-D-T-S-Y-S-E-R-P-I-P"} +{"text": "### FUNCTION May contribute to the transparency and refractive index of the lens ### SEQUENCE -L-I-R-R-P-L-F-S-F-L-T-P-T-R-I-F-D-Q-S-F-G-E-H-L-S-E-S-E-L-F-P-T-S-G-A-L-S-P-F-L-L-R-S-P-F-L-R-T-P-S-W-L"} +{"text": "### FUNCTION Transcriptional regulator Involved in the initiation of neuronal differentiation Activates transcription by binding to the E box-containing promoter ### SEQUENCE -R-D-D-F-S-S-D-D-M-K-S-D-D-E-S-S-Q-K-E-M-K-S-S-R-G-R-T-S-S-I-N-E-D-E-D-L-N-P-E-Q-K-V-E-R-E-K-E-R-R-M-A-N-N-A-R-E-R-L-R-V-R-D-I-N-E-A-F-K-E-L-G-R-M-C-Q-L-H-L-K-S-E-K-P-Q-T-K-L-L-I-L-H-Q-A-V-A-V-I-L-N-L-E-Q-Q-V-R-E-R-N-L-N-P-K-A-A-C-L-K-R-R-E-E-E-K-V-S-A-V-S-A-E-P-P-N-T-H-P-G-V-H-P-G-L-T-D-T-T-N-P-M-G-H-M"} +{"text": "### FUNCTION Transcriptional activator ### SEQUENCE -M-S-V-F-Y-P-I-H-C-T-D-Y-L-R-S-A-E-M-T-E-V-I-M-N-T-Q-S-M-D-E-I-G-L-S-P-R-K-D-S-Y-Q-I-F-P-D-P-S-D-F-E-R-C-C-K-L-K-D-R-L-P-S-I-V-V-E-P-T-E-G-D-V-E-S-G-E-L-R-W-P-P-E-E-F-V-V-D-E-D-K-E-G-T-C-D-Q-T-K-K-E-N-E-Q"} +{"text": "### FUNCTION Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function ### SEQUENCE -M-S-Y-K-N-I-Y-Y-S-D-K-Y-T-D-E-H-F-E-Y-R-H-V-M-L-P-K-E-L-A-K-Q-V-P-K-T-H-L-M-S-E-E-E-W-R-R-L-G-V-Q-Q-S-L-G-W-V-H-Y-M-I-H-E-P-E-P-H-I-L-L-F-R-R-P-L-P-K-D-Q-Q-K"} +{"text": "### FUNCTION Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments ### SEQUENCE -M-H-Y-I-D-W-V-I-L-L-T-F-A-A-A-L-I-V-C-L-T-P-K-P-E-P-C-I-I-T-V-S-G-A-S-A-T-V-S-N-C-P-N-P-E-L-L-T-D-L-V-K-A-L-K-P-A-K-P-V"} +{"text": "### FUNCTION Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata, ### SEQUENCE -M-P-L-Q-P-P-P-D-H-T-W-A-V-R-I-I-A-L-G-L-A-V-T-A-L-I-F-T-S-T-R-D-T-S-R-H-V-G-D-P-S-H-S-L-P-F-G-G-H-Y-R-D-G-S-K-V-I-H-Y-N-S-P-R-S-S-K-P-S-N-H-T-P-Y-L-L-F-A-P-I-G-I-I-L-L-I-H-A-L-H-R-L-G-N-S-A-H-I-C-R-C-T-H-C-M-P-H-S-Q-T"} +{"text": "### FUNCTION Has low cytotoxic activity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-H-N-T-Q-L-P-F-I-Y-K-T-C-P-E-G-K-N-L-C-F-K-A-T-L-K-K-F-P-L-K-F-P-V-K-R-G-C-A-D-N-C-P-K-N-S-A-L-L-K-Y-V-C-C-S-T-D-K-C-N"} +{"text": "### FUNCTION Component of the DNA-dependent RNA polymerase that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates ### SEQUENCE -M-F-S-K-S-Y-Q-I-T-K-E-M-Y-E-A-R-G-W-Q-I-I-K-E-D-E-L-T-I-L-A-K-V-N-S-R-E-N-T-N-P-E-F-A-I-A-K-F-I-K-T-T-Q-E-I-K-S-P-P-L-S-Q-I-I-D-F-S-S-N-E-Y-V-C-V-T-I-I-C-D-G-S-I-T-T-N-V-K-K-I-E-Q-T-T-K-G-K-V-E-I-F-H-N-K-D-L-Q-M-N-I-T-K-Y-H-L-Q-P-L-F-N-K-L-L-D-E-E-A-K-D-F-K-K-K-Y-I-K-C-K-I-E-N-G-K-K-I-I-L-Q-S-F-P-S-M-S-K-S-D-P-I-A-R-F-F-K-Y-Q-S-G-D-V-I-K-I-T-N-K-D-G-F-V-S-Y-R-I-V-K"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-Y-Q-Q-K-Y-F-E-K-P-V-Y-Y-L-Q-R-N-D-F-D-D-N-G-N-L-I-V-P-E-L-R-N-K-K-V-I-I-M-I-Q-A-N-Y-C-G-H-C-T-N-A-K-G-D-Y-Y-K-A-A-K-Y-I-K-E-L-E-K-N-G-G-T-S-Y-K-N-K-V-V-F-A-T-I-Q-A-D-G-D-E-E-G-E-K-E-L-N-Q-I-L-D-K-I-K-P-T-F-V-G-F-P-D-Y-V-L-Y-V-N-G-K-R-I-E-D-D-G-P-P-G-R-N-F-N-N-I-V-N-Y-V-M-G"} +{"text": "### FUNCTION May function as a phosphatase ### SEQUENCE -M-K-N-I-F-L-D-L-D-N-T-L-I-C-A-E-P-F-E-D-I-T-D-L-G-R-F-K-E-R-A-S-H-F-D-F-K-N-M-E-D-Y-Y-L-I-C-G-R-P-Y-L-Q-P-F-L-D-Y-L-F-K-N-F-N-V-H-I-W-T-A-A-S-K-G-Y-A-S-F-I-I-E-E-F-I-L-K-K-D-P-S-R-K-I-N-L-V-L-F-D-H-H-C-R-V-S-K-R-V-Y-K-K-E-K-A-S-K-K-L-E-M-L-W-T-I-W-K-L-Q-E-F-D-K-E-N-T-F-I-I-D-D-L-E-E-V-K-E-S-Q-V-K-N-C-F-S-V-K-P-F-F-F-M-E-N-D-S-E-Y-D-Q-E-L-M-R-L-K-D-V-L-N-R-H-L-N"} +{"text": "### FUNCTION FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation ### SEQUENCE -M-T-D-I-D-P-H-I-W-G-P-S-F-W-S-T-Y-H-L-Y-A-S-S-Y-P-I-H-P-T-P-I-I-M-D-A-A-R-S-F-V-K-T-I-P-F-T-L-P-C-S-S-C-T-D-H-A-F-A-Y-I-K-N-I-Q-K-Q-D-P-D-L-I-S-I-V-S-S-K-M-L-F-E-K-F-F-I-D-F-H-N-S-V-N-Y-R-L-G-K-P-L-L-P-E-S-V-A-R-K-K-W-R-F"} +{"text": "### FUNCTION Probably involved in the viral transport within, and between cells ### SEQUENCE -M-M-V-C-L-P-D-W-L-F-L-L-F-I-F-S-I-L-L-Q-S-G-T-N-F-Y-G-T-F-Q-S-G-S-I-S-R-Q-L-S-S-L-S-S-S-I-D-Q-L-F-L-K-V-Q-Q-V-V-Y-T-R-Y-P-S-R-D-R-V-S-D-P-R-R-R-R-G-L-S-S-I-P-E-G-S-E-E-A-T-E-V"} +{"text": "### FUNCTION Superoxide dismutase-like protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-G-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-R-G-C-E-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-F-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V"} +{"text": "### FUNCTION Superoxide dismutase-like protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-R-G-C-D-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-Y-I-N-E-K-N-N-T-F-S-Y-N"} +{"text": "### FUNCTION Superoxide dismutase-like protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-R-G-C-D-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-Y-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V"} +{"text": "### FUNCTION Involved in the viral transport within, and between cells ### SEQUENCE -M-D-P-Q-S-A-I-Y-T-L-P-R-V-P-T-A-A-P-T-T-G-G-V-S-W-S-H-V-G-E-V-A-I-L-S-F-V-A-L-I-C-I-Y-L-L-Y-L-W-V-L-R-D-L-I-L-V-L-K-A-R-R-G-R-S-T-E-E-L-I-F-G-S-E-A-V-D-R-R-H-P-I-P-N-T-L-V-P-T-A-P-V-H-P-G-P-F-V-P-G-Q-G"} +{"text": "### FUNCTION Involved in the viral transport within, and between cells ### SEQUENCE -M-D-P-Q-S-A-V-Y-S-L-P-R-V-P-T-A-A-P-P-N-A-G-V-P-W-S-H-V-G-E-V-A-V-L-S-F-V-A-L-I-C-I-Y-L-L-Y-L-W-V-L-R-D-L-I-L-V-L-K-A-R-R-G-R-S-T-E-E-L-I-F-G-S-E-A-V-D-R-R-S-P-I-P-N-T-L-E-P-T-A-P-V-H-P-G-P-F-V-P-G-S-G"} +{"text": "### FUNCTION Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme ### SEQUENCE -M-A-N-S-L-R-G-E-V-L-T-L-Y-K-N-L-L-Y-L-G-R-D-Y-P-K-G-A-D-Y-F-K-R-R-L-K-N-V-F-L-K-N-K-D-V-E-D-P-E-K-I-K-E-L-I-A-R-G-E-F-V-M-K-E-L-E-A-L-Y-F-L-R-K-Y-R-A-M-K-Q-R-Y-Y-S-D-T-K-V"} +{"text": "### FUNCTION May activate the NF-kappa-B signaling pathway ### SEQUENCE -M-V-C-I-P-C-I-V-I-P-V-L-L-W-I-F-K-K-F-L-E-P-Y-I-Y-P-V-V-S-R-I-W-P-K-K-A-V-Q-Q-S-G-D-K-N-M-S-K-V-D-C-K-G-A-G-T-N-G-L-P-T-K-G-P-T-E-V-S-D-K-K-K-D"} +{"text": "### FUNCTION Has an antimicrobial activity ### SEQUENCE -S-V-V-L-L-I-C-L-L-L-L-G-Q-V-D-G-S-P-V-P-E-K-S-S-V-K-K-R-L-R-R-M-T-P-F-W-R-G-V-S-L-R-P-I-G-A-S-C-R-D-D-S-E-C-I-T-R-L-C-K-K-R-R-C-S-L-S-V-A-Q-E"} +{"text": "### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-E-C-S-K-T-G-K-C-N-C-G-T-S-C-T-C-T-N-C-S-C-K-C-C-K-K-S-C-C-S-C-C-P-S-G-C-S-K-C-A-S-G-C-V-C-K-G-N-S-C-D-K-S-C-C-Q"} +{"text": "### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -V-R-V-V-V-L-A-L-V-A-Q-V-T-L-S-Q-H-W-S-Y-G-W-L-P-G-G-K-R-S-V-G-E-L-E-A-T-I-K-M-M-D-T-G-G-V-V-A-L-P-E-E-T-S-A-H-V-S-E-R-L-R-P-Y-D-V-I-L-K-K-W-M-P-H-K"} +{"text": "### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-E-W-K-G-R-V-L-V-Q-L-L-M-L-V-C-V-L-E-V-S-L-C-Q-H-W-S-Y-G-W-L-P-G-G-K-R-S-V-G-E-V-E-A-T-I-R-M-M-D-G-G-D-T-L-L-S-I-P-A-D-T-P-M-E-Q-L-S-P-I-H-I-M-N-E-V-D-A-E-G-F-P-L-K-E-Q-R-F-P-N-R-R-G-R-M"} +{"text": "### FUNCTION May be involved in transcriptional regulation Modulates various viral and cellular promoters in a promoter context-dependent manner Does not bind DNA directly ### SEQUENCE -M-E-N-T-R-S-E-N-E-E-Q-P-E-S-T-L-K-I-D-E-E-Q-P-A-V-E-Q-S-P-E-N-Q-C-S-E-E-D-Q-S-S-E-D-L-S-S-E-E-Q-S-S-E-E-E-F-F-P-E-E-L-L-P-E-L-L-P-E-M-L-L-S-E-D-R-P-P-Q-E-C-L-S-Q-K-N-Q-F-E-D-R-I-P-M-E-Q-P-P-C-G-V-G-K-H-K-L-E-E-G-S-F-K-E-R-L-A-R-I-R-P-Q-F-I-G-D-I-H-G-R-N-L-S-N-E-E-M-I-Q-A-A-D-E-L-E-E-M-K-R-V-R-N-K-L-M-I-M-H-W-K-A-K-R-S-R-P-Y-P-I"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-A-P-G-L-V-V-G-L-N-K-G-K-V-L-T-K-R-Q-L-P-E-R-P-S-R-R-K-G-Q-L-S-K-R-T-S-F-V-R-S-I-V-R-E-V-A-G-F-A-P-Y-E-R-R-V-M-E-L-I-R-N-S-Q-D-K-R-A-R-K-L-A-K-K-R-L-G-T-L-K-R-A-K-G-K-I-E-E-L-T-S-V-I-Q-S-S-R-L-A-H"} +{"text": "### FUNCTION Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems ### SEQUENCE -M-A-H-V-L-P-D-L-P-Y-A-Y-N-A-L-E-P-F-I-S-Q-Q-I-M-E-L-H-H-K-K-H-H-Q-T-Y-V-N-S-L-N-A-A-E-Q-A-Y-A-K-A-S-T-P-K-E-R-I-A-L-Q-S-A-L-K-F-N-G-G-G-H-I-N-H-S-L-F-W-K-N-L-A-P-A-K-S-E-G-K-G-N-G-G-A-L-A-D-G-P-L-K-S-A-I-E-Q-N-W-G-S-V-D-N-F-I-K-E-F-N-A-T-T-A-A-I-Q-G-S-G-W-G-W-L-G-L-N-P-A-T-K-R-L-E-I-T-T-T-A-N-Q-D-P-L-L-S-H-V-P-I-I-G-V-D-I-W-E-H-A-F-Y-L-Q-Y-L-N-V-K-A-D-Y-L-A-A-I-W-I-V-I-N-F-K-E-A-E-R-R-L-I-E-A-T-K"} +{"text": "### FUNCTION Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair ### SEQUENCE -M-S-K-Q-P-I-S-N-V-R-S-I-Q-A-N-I-N-I-P-M-G-A-F-R-P-G-A-G-Q-P-P-R-R-K-E-S-T-P-G-T-A-E-G-A-P-A-T-P-E-E-K-K-P-V-P-G-M-K-K-F-P-G-P-V-V-N-L-S-E-I-Q-N-V-K-S-E-L-K-Y-V-P-K-G-E-Q"} +{"text": "### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-Y-Y-S-G-Y-S-G-G-L-G-Y-G-Y-G-S-S-F-G-G-P-G-C-G-C-N-S-I-R-R-L-G-C-G-S-G-Y-G-G-F-G-Y-G-S-G-Y-G-G-Y-G-Y-G-S-D-Y-G-G-Y-G-Y-G-S-S-Y-G-G-Y-G-C-G-C-R-R-P-S-C-C-G-R-Y-G-F-S-N-F-Y"} +{"text": "### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-C-G-Y-Y-G-N-Y-Y-G-G-R-G-Y-G-C-C-G-C-G-G-L-G-Y-G-Y-G-G-L-G-C-G-Y-G-S-Y-Y-G-C-G-Y-R-G-L-G-C-G-Y-G-Y-G-C-G-Y-G-S-R-S-L-Y-G-C-G-Y-G-C-G-S-G-Y-G-S-G-F-G-Y-Y-Y"} +{"text": "### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-H-Y-S-S-Y-Y-G-G-L-G-Y-G-Y-G-S-F-G-G-P-G-C-G-C-N-S-I-R-R-L-V-G-F-G-S-G-Y-G-G-F-G-Y-G-S-G-F-G-G-F-G-Y-G-S-G-Y-G-G-Y-G-Y-G-S-G-F-R-G-Y-G-C-G-C-R-R-P-S-C-C-G-G-Y-G-F-S-S-F-Y"} +{"text": "### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-Y-Y-N-S-Y-Y-G-G-L-G-Y-G-S-G-G-Y-G-G-L-G-Y-G-Y-G-C-G-C-G-S-F-R-R-L-G-Y-G-C-G-F-G-G-Y-G-G-F-G-Y-G-S-G-Y-G-G-F-S-S-G-S-G-Y-G-G-F-G-Y-G-Y-R-R-P-L-S-Y-G-G-Y-G-F-S-T-F-Y"} +{"text": "### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-Y-Y-S-G-Y-S-G-G-L-G-Y-G-Y-G-S-S-F-G-G-L-G-C-G-C-N-S-I-R-R-L-G-C-G-S-G-Y-G-G-F-G-Y-G-S-G-Y-G-G-F-G-G-F-G-Y-G-S-G-Y-G-G-Y-G-Y-G-S-G-Y-G-G-F-G-G-F-G-Y-G-S-G-Y-G-G-F-G-Y-G-S-G-Y-G-G-F-G-G-F-G-Y-G-S-G-Y-G-G-Y-G-Y-G-S-G-F-G-G-Y-G-Y-G-S-G-F-R-G-Y-G-C-G-C-R-R-S-S-C-C-G-G-Y-G-F-S-S-F-Y"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-E-A-T-R-V-R-R-R-E-R-K-N-I-T-S-G-V-A-H-V-N-S-S-F-N-N-T-M-I-T-I-T-D-A-Q-G-N-A-I-A-W-S-S-A-G-A-K-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-I-A-A-E-D-C-A-K-K-A-Q-E-H-G-M-K-S-L-E-V-E-V-C-G-P-G-S-G-R-E-S-A-L-R-A-L-Q-A-A-G-F-M-I-T-S-I-R-D-V-T-P-I-P-H-N-G-C-R-P-R-K-K-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-T-A-K-R-V-V-I-A-L-T-Y-I-H-G-I-G-T-K-F-A-Q-E-I-I-E-K-V-G-I-P-A-E-R-R-V-H-Q-L-T-D-A-E-V-L-Q-I-R-E-T-I-D-R-D-Y-Q-V-E-G-D-L-R-R-E-T-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-H-T-N-A-R-T-R-K-G-P-A-K-A-I-A-G-K-K-K"} +{"text": "### FUNCTION Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity ### SEQUENCE -M-S-R-I-D-T-P-A-A-S-R-M-Q-T-I-A-R-N-P-V-M-I-A-L-V-M-T-L-A-L-A-G-C-A-S-K-K-N-L-P-N-D-A-A-G-L-G-L-G-A-G-A-A-T-P-G-S-Q-Q-D-F-T-V-N-V-G-D-R-I-F-F-D-T-D-S-T-S-I-R-A-D-A-Q-A-T-L-D-R-Q-A-Q-W-L-A-K-Y-P-N-Y-G-I-T-I-E-G-H-A-D-E-R-G-T-R-E-Y-N-L-A-L-G-A-R-R-A-A-A-T-R-D-Y-L-V-S-R-G-V-P-G-N-R-M-R-T-I-S-Y-G-K-E-K-P-V-A-V-C-D-D-I-S-C-W-S-Q-N-R-R-A-V-T-V-L-G-G-A-G-S"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-K-Y-R-I-K-K-N-D-D-F-Q-K-V-F-R-R-G-K-S-F-A-N-R-Q-F-V-V-Y-T-L-K-Q-E-E-A-S-H-F-R-I-G-L-S-V-S-K-K-I-G-N-A-V-C-R-N-R-I-K-R-Y-I-R-Q-S-F-H-E-L-E-S-Q-I-N-P-E-N-E-Y-I-I-I-A-R-K-P-A-A-N-M-D-F-H-E-V-K-K-S-L-I-H-V-L-K-V-G-R-V-L-K-Q-K-P-N-N-S-K"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-R-G-M-G-N-M-Q-G-M-M-K-Q-M-Q-K-M-Q-K-E-M-A-K-A-Q-A-D-L-E-A-Q-E-F-T-G-T-A-G-G-G-M-V-T-V-K-A-I-G-K-R-V-I-T-D-V-V-I-N-E-E-V-V-D-P-E-D-I-E-M-L-Q-D-L-V-L-A-A-T-N-D-V-L-K-Q-I-E-D-T-T-S-Q-T-M-G-K-F-T-Q-G-L-N-L-P-G-M"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-T-K-L-M-D-S-F-M-K-L-P-G-I-G-P-K-S-A-A-R-L-A-F-Y-V-L-D-M-K-E-D-D-V-L-D-F-A-K-A-L-V-D-A-K-R-N-L-S-F-C-S-V-C-G-H-I-T-D-K-D-P-C-Y-I-C-S-D-T-S-R-D-R-S-V-L-C-V-V-Q-E-S-K-D-V-I-A-M-E-K-M-R-D-F-H-G-L-Y-H-V-L-H-G-T-I-S-P-M-D-G-I-G-P-E-D-I-N-I-P-D-L-L-K-R-L-Q-D-D-T-I-E-E-V-I-L-A-T-N-P-N-V-E-G-E-A-T-A-M-Y-I-S-R-L-L-R-P-S-G-I-K-V-T-R-I-A-H-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-M-E-G-R-R-E-V"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-K-R-F-M-Q-I-W-K-P-A-V-V-G-F-L-L-L-T-L-V-C-G-V-I-Y-P-G-V-V-T-I-I-A-G-A-A-F-Q-D-K-A-N-G-S-I-I-E-G-K-L-A-D-G-E-T-G-K-Y-G-S-T-E-I-G-Q-T-F-T-Q-P-E-Y-L-I-G-R-A-A-S-D-G-A-A-T-N-L-N-P-T-S-E-E-Q-K-Q-L-V-E-K-R-I-T-W-W-H-K-L-D-P-A-N-N-R-V-I-P-M-D-L-V-T-A-S-A-S-G-V-D-P-D-I-S-E-A-A-A-A-Y-Q-V-D-R-I-S-R-E-R-G-I-S-T-K-V-V-K-E-I-I-A-E-N-T-S-K-R-L-L-G-F-W-G-E-P-T-V-N-V-L-Q-V-N-V-A-L-D-S-L-K-M"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-D-A-R-D-I-I-K-R-P-V-V-T-E-E-S-T-S-I-L-D-D-K-K-Y-T-F-E-V-D-T-R-A-T-K-T-Q-V-K-Y-A-I-E-E-I-F-D-V-K-V-A-K-V-N-V-M-N-Y-K-G-K-L-K-R-M-G-R-Y-A-G-Y-T-N-K-R-R-K-A-I-V-T-V-T-A-D-S-K-E-I-Q-F-F-E-V"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-S-E-V-T-S-A-K-A-V-A-K-T-V-R-I-A-P-R-K-A-R-I-V-I-D-L-I-R-G-K-Q-V-G-E-A-I-A-I-L-K-Y-T-P-R-S-A-S-P-I-I-E-K-V-L-K-S-A-I-A-N-A-E-H-N-Y-D-L-D-I-N-N-L-V-V-E-E-A-F-V-D-E-G-P-T-L-K-R-F-R-P-R-A-Q-G-R-A-S-A-I-N-K-R-T-S-H-I-T-V-V-V-S-E-V-K-E-G"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-Y-R-R-E-F-R-G-N-M-R-G-R-A-K-G-G-T-E-V-A-F-G-E-Y-G-L-Q-A-V-E-A-S-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-S-K-P-I-G-V-R-M-G-K-G-K-G-A-P-E-G-W-V-S-P-V-K-R-G-K-I-M-F-E-I-A-G-V-P-E-D-V-A-R-E-A-L-R-L-A-A-H-K-L-P-V-K-T-K-I-V-K-R-E-E-I-G-G-E-A-N-E-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-D-R-N-Q-R-K-V-Y-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-Y-K-K-H-G-L-Y-G-K-R-V-K-Y-S-K-K-F-K-A-H-D-E-N-N-I-A-K-T-G-D-V-V-R-I-S-E-T-R-P-L-S-A-T-K-H-F-R-L-L-E-V-V-E-E-A-V-I-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-M-K-V-A-D-N-S-G-A-R-E-V-L-T-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-V-V-V-C-T-V-K-Q-A-T-P-G-G-V-V-K-K-G-E-V-V-K-A-V-I-V-R-T-K-S-G-A-R-R-Q-D-G-S-Y-I-K-F-D-E-N-A-C-V-I-I-R-D-D-K-S-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-N-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-H-V-K-K-G-D-K-V-K-V-I-T-G-K-D-K-G-K-S-G-K-V-L-A-A-F-P-K-K-D-R-V-L-I-E-G-I-N-M-V-K-K-H-T-K-P-S-N-I-N-P-Q-G-G-I-L-N-V-E-A-P-I-H-V-S-N-V-M-L-I-D-P-K-T-G-E-P-T-R-V-G-Y-E-V-K-G-D-K-K-V-R-V-A-K-K-S-G-E-V-I-D-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-D-Q-Y-L-K-E-I-V-P-A-L-M-S-K-F-N-Y-D-S-V-M-E-V-P-K-I-D-K-I-V-I-N-T-G-V-G-D-A-T-A-N-A-K-V-L-D-S-A-V-E-E-L-A-L-I-T-G-Q-K-P-V-I-T-K-A-K-N-S-I-A-G-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-R-M-Y-D-F-L-D-K-L-V-T-V-S-L-P-R-V-R-D-F-R-G-V-S-K-K-A-F-D-G-R-G-N-Y-T-L-G-V-R-E-Q-L-I-F-P-E-I-D-Y-D-Q-V-S-K-V-R-G-M-D-V-V-I-V-T-T-A-K-S-D-E-E-S-H-E-L-L-T-Q-L-G-M-P-F-Q-K"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-T-I-V-I-P-A-G-V-T-V-T-L-N-G-S-T-A-T-V-K-G-P-K-G-E-L-V-K-E-F-N-P-E-I-T-I-N-I-E-G-N-E-I-N-V-S-R-P-T-D-N-K-N-H-R-A-L-H-G-T-T-R-A-I-L-N-N-M-V-V-G-V-S-E-G-Y-E-K-K-L-E-L-I-G-V-G-Y-R-A-Q-K-Q-G-D-K-L-V-L-N-V-G-Y-S-H-P-V-E-F-V-A-P-K-G-V-E-I-E-V-P-A-N-T-Q-V-I-V-K-G-Y-N-K-E-H-V-G-E-L-A-A-N-I-R-A-V-R-P-P-E-P-Y-K-G-K-G-I-R-Y-E-G-E-H-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-T-K-I-D-K-N-K-V-R-K-K-R-H-A-R-V-R-S-K-I-S-G-T-E-S-R-P-R-L-N-V-F-R-S-N-K-N-I-Y-A-Q-V-I-D-D-V-N-G-V-T-L-A-S-A-S-N-L-D-K-D-F-G-S-A-E-S-K-V-D-A-A-S-K-V-G-E-L-V-A-K-R-A-S-E-K-G-I-T-S-V-T-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-N-G-L-E-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-P-E-Q-I-D-G-N-K-L-D-L-E-E-R-V-V-T-I-N-R-V-A-K-V-V-K-G-G-R-R-F-R-F-T-A-L-V-V-V-G-D-K-N-G-H-V-G-F-G-T-G-K-A-Q-E-V-P-D-A-I-R-K-A-V-E-D-A-K-K-N-M-V-F-V-P-T-V-D-T-T-I-P-H-T-V-V-G-H-F-G-G-G-E-I-L-L-K-P-A-S-A-G-S-G-V-T-A-G-G-P-V-R-A-V-L-E-L-A-G-V-A-D-V-S-S-K-S-L-G-S-N-T-P-I-N-M-V-R-A-T-I-D-G-I-K-Q-L-K-N-A-E-D-V-A-K-L-R-G-K-T-V-E-E-L-L-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-S-E-G-S-R-K-E-R-N-R-V-G-R-G-T-G-S-G-N-G-K-T-S-G-R-G-H-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-L-P-L-F-R-R-I-P-K-R-G-F-T-N-I-N-R-K-E-F-A-I-V-N-L-D-V-L-N-R-F-E-D-G-T-E-V-T-P-E-L-L-I-E-T-G-I-I-R-N-E-K-S-G-I-K-I-L-S-D-G-N-I-E-K-K-L-T-V-K-A-N-K-F-S-A-A-A-K-E-A-I-E-A-A-G-G-K-T-E-V-I"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-Y-M-A-K-P-G-E-V-E-R-K-W-Y-V-I-D-A-T-G-V-S-L-G-R-L-S-S-E-V-A-S-I-L-R-G-K-N-K-P-Q-F-T-P-H-I-D-T-G-D-F-V-I-I-I-N-A-G-K-I-G-L-T-G-K-K-A-T-D-K-I-Y-Y-R-H-S-Q-Y-P-G-G-L-K-S-R-T-A-G-E-M-R-T-N-N-P-E-K-L-L-E-L-S-I-K-G-M-L-P-K-N-S-L-G-R-Q-L-F-K-K-L-H-V-Y-G-G-S-E-H-E-H-A-A-Q-K-P-E-V-Y-E-L-R-G"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-D-L-K-N-L-T-Q-E-E-R-S-E-L-S-L-I-D-V-A-H-F-I-L-E-Q-R-K-E-T-I-L-F-P-E-L-V-K-E-I-Q-A-F-L-G-L-K-D-A-E-I-R-E-R-L-V-Q-F-Y-T-D-M-N-I-D-G-N-F-I-S-L-G-N-N-T-W-G-L-R-A-W-Y-P-M-D-A-I-D-E-E-V-Q-T-Q-T-T-P-K-K-K-R-K-S-D-D-D-D-D-E-D-E-E-I-L-D-D-D-V-D-Y-D-D-E-E-I-V-E-E-L-G-E-E-E-I-S-L-A-D-V-L-L-D-E-D-E-D-D-D-D-H-L-P-D-G-I-E-G-D-L-A-T-V-E-D-D-Y-T-D-G-D-Y-T-E-D-P-E-D-K"} +{"text": "### FUNCTION Involved in the decoration of cell wall teichoic acid with galactose and glucose ### SEQUENCE -M-S-R-V-R-Q-L-L-D-K-L-P-W-Y-T-D-N-I-H-S-I-L-M-Y-L-I-M-G-G-F-T-T-L-I-N-I-V-T-F-W-L-C-T-D-V-L-N-W-D-Y-R-I-A-N-T-I-A-W-V-A-S-V-L-F-A-Y-F-S-N-K-K-Y-V-F-E-S-Y-T-P-T-W-K-E-K-A-R-E-V-S-S-F-F-G-F-R-F-L-T-Y-I-V-D-F-L-V-M-I-L-L-I-S-G-L-G-I-N-E-L-W-A-K-I-W-T-N-V-I-V-L-I-L-N-Y-V-F-S-K-W-I-I-F-K-V-R-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-L-Q-P-H-L-V-I-G-S-A-F-T-F-G-D-A-F-F-T-L-F-A-F-A-I-L-L-V-L-I-R-I-Y-A-W-K-P-L-M-G-V-M-K-E-R-E-E-H-I-G-S-E-I-D-A-A-E-E-S-R-A-Q-A-E-Q-L-L-A-E-Q-K-S-V-L-Q-Q-A-R-V-E-S-Q-T-M-I-E-N-A-K-Q-L-G-E-K-E-R-E-E-I-V-K-T-A-R-R-E-S-E-R-I-K-E-E-A-K-A-D-I-A-R-E-K-E-D-A-I-S-A-L-R-E-Q-V-G-S-L-S-V-L-I-A-S-K-V-I-E-K-N-L-D-E-K-E-Q-S-N-L-I-Q-D-Y-I-E-R-L-G-D-D-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-K-D-L-E-V-A-G-R-Y-A-N-A-L-F-Q-V-A-Q-D-K-D-L-V-D-V-F-S-E-E-L-T-E-L-K-A-A-L-N-A-N-K-D-F-V-K-L-L-E-N-P-T-F-T-T-E-Q-K-K-N-L-A-S-A-V-F-E-K-I-N-P-T-L-R-D-F-I-Y-L-L-I-D-R-S-R-E-D-Y-L-S-V-I-A-D-V-Y-Q-K-R-V-N-D-L-R-G-V-A-D-A-D-V-Y-S-V-V-P-L-S-E-Q-E-L-T-A-L-S-R-V-F-A-A-K-M-N-K-T-K-L-N-I-Q-N-H-I-D-K-S-L-L-G-G-V-K-V-V-I-G-T-R-I-Y-D-D-S-L-K-T-K-L-K-D-M-E-R-Q-I-K-A"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-G-S-L-N-V-S-I-V-T-P-D-G-P-V-Y-E-G-V-A-Q-M-V-I-A-R-T-K-A-G-E-L-G-I-L-P-G-H-V-P-L-V-A-P-L-K-I-D-I-V-R-L-K-V-E-S-G-E-E-W-V-A-V-N-G-G-F-M-E-V-N-G-E-E-V-N-I-L-A-D-T-A-E-R-E-Q-D-I-D-I-D-R-A-E-K-A-K-Q-R-A-E-E-E-L-S-R-A-K-E-Q-K-V-D-E-V-M-A-R-L-A-L-Q-R-A-I-N-R-I-H-A-K-E-H-N"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-L-I-P-T-V-I-E-Q-T-S-R-G-E-R-A-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-G-S-A-I-D-D-N-V-A-N-S-I-V-S-Q-L-L-F-L-D-A-Q-D-P-E-K-D-I-F-L-Y-I-N-S-P-G-G-S-I-S-A-G-M-A-I-Y-D-T-M-N-F-V-K-A-D-V-Q-T-I-G-M-G-M-A-A-S-M-G-S-F-L-L-T-A-G-A-N-G-K-R-F-A-L-P-N-A-E-I-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-T-E-I-E-I-A-A-R-H-I-L-K-I-K-E-R-M-N-T-I-M-A-E-K-T-G-Q-P-Y-E-V-I-A-R-D-T-D-R-D-N-F-M-T-A-Q-E-A-K-D-Y-G-L-I-D-D-I-I-V-N-K-S-G-L-K-G"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-L-P-K-D-L-L-Y-T-E-E-H-E-W-V-K-A-E-D-G-S-Y-I-I-G-I-T-D-F-A-Q-D-Q-L-G-D-I-V-F-V-E-L-P-E-V-G-D-T-V-T-K-G-D-S-I-G-S-I-E-S-V-K-T-V-S-D-F-Y-A-P-V-T-G-K-V-V-A-V-N-E-T-L-E-D-E-P-E-L-I-N-S-N-P-Y-D-T-G-W-I-L-K-L-T-E-V-E-E-A-D-V-T-A-L-L-S-S-D-D-Y-E-K-G-L-D"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Y-F-L-Y-V-G-I-F-G-A-L-G-G-M-C-R-Y-A-M-N-L-W-L-G-G-G-D-F-P-S-A-T-L-A-V-N-L-I-G-C-F-L-L-A-F-I-M-P-F-L-A-E-K-S-R-I-S-L-V-L-L-N-G-I-G-T-G-F-I-G-A-F-T-T-F-S-A-F-S-V-D-T-I-E-L-L-Q-Q-G-E-V-V-L-A-I-S-Y-I-L-V-S-L-I-G-G-L-V-M-V-K-F-G-R-R-F-S-N-K-L-L-R-R-G-A-H-H-V-D"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-I-N-F-L-L-V-G-F-G-A-S-L-G-A-M-L-R-Y-G-I-S-I-F-V-K-S-K-W-K-T-D-F-P-Y-A-T-F-F-I-N-I-T-G-S-F-L-L-G-F-L-V-S-T-A-L-G-P-M-W-Q-L-F-L-G-T-G-F-M-G-G-Y-T-T-F-S-T-F-K-V-E-S-M-E-L-K-W-K-A-N-F-Q-V-L-F-S-Y-V-G-L-T-Y-L-C-G-L-I-A-A-F-I-G-I-M-L-G-V"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-I-E-V-L-E-A-E-E-K-T-A-S-G-I-V-L-P-D-S-A-K-E-K-P-Q-S-G-K-I-V-A-V-G-S-G-R-V-L-D-N-G-T-K-E-P-L-E-V-A-E-G-D-T-V-I-F-A-K-Y-S-G-T-E-V-T-Y-E-G-T-D-Y-L-I-L-R-E-S-D-I-L-A-I-S-K"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-K-K-M-L-V-E-F-R-D-F-A-L-K-G-N-V-L-D-L-A-V-A-V-V-I-G-A-A-F-G-K-I-V-S-S-L-V-N-N-I-I-M-P-F-V-G-V-L-L-G-G-L-D-F-S-D-L-S-F-K-V-G-K-S-V-I-Q-Y-G-A-F-I-Q-S-I-V-D-F-V-I-I-A-F-A-I-F-I-F-V-K-V-L-T-S-F-I-K-K-K-E-Q-P-T-E-E-T-P-V-P-P-T-E-E-Y-L-K-E-I-R-D-L-L-K-E-Q-Q-K"} +{"text": "### FUNCTION Essential cell division protein ### SEQUENCE -M-S-N-V-A-Y-K-S-N-L-E-P-N-R-V-H-R-E-A-E-Q-P-K-K-Q-I-L-K-R-G-Q-M-T-L-G-E-K-V-I-I-T-I-A-L-A-I-V-L-V-V-A-F-R-I-I-S-V-Q-A-Q-I-Y-T-V-N-Q-E-I-Q-T-K-E-T-K-I-L-E-Q-Q-K-S-N-E-D-L-K-V-E-V-K-D-L-G-R-Y-E-R-I-L-K-I-A-K-E-K-G-L-K-L-D-G-D-N-V-K-V-V-D-G-Q"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-G-L-S-N-K-F-K-S-F-F-F-L-D-E-E-E-E-Y-Y-E-E-E-V-A-R-E-P-E-P-M-Q-K-K-T-K-K-E-K-P-S-K-N-R-F-Y-A-V-E-E-E-D-A-K-V-V-S-M-Q-G-A-Q-F-S-S-R-M-V-L-A-E-P-R-V-Y-A-E-A-Q-E-L-A-D-Y-L-K-D-Y-K-T-V-V-V-N-L-Q-R-I-S-H-D-Q-A-T-R-I-V-D-F-L-S-G-T-V-Y-A-L-G-G-D-I-Q-R-V-G-N-N-I-F-L-C-T-P-D-N-V-E-V-N-G-S-I-S-E-M-L-D-E-Q-N-F-M"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-A-I-K-V-H-I-G-K-T-V-A-L-M-N-D-N-I-D-T-D-Q-I-I-P-K-S-F-L-K-R-I-E-R-T-G-F-G-E-F-L-F-D-S-W-R-Y-L-P-N-R-K-P-N-P-D-F-P-L-N-A-P-D-R-Q-E-A-T-I-L-I-T-G-D-N-F-G-C-G-S-S-R-E-H-A-A-W-A-L-L-D-Y-R-F-R-V-I-I-A-G-S-Y-S-D-I-F-Y-M-N-C-T-K-N-G-V-L-P-I-V-L-P-R-E-A-R-E-K-L-A-K-I-T-A-E-E-K-V-T-I-D-L-P-K-Q-Q-V-I-S-S-V-G-T-Y-P-F-E-I-D-A-T-W-K-N-K-F-I-N-G-L-D-D-I-A-I-T-F-E-H-I-D-A-I-K-A-Y-E-Q-K-V-D-S-I"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-N-R-E-E-Q-L-G-V-L-E-S-L-L-F-A-A-G-D-A-G-L-S-T-E-Q-L-T-E-V-M-E-I-T-H-I-E-A-L-N-L-L-E-L-L-S-E-R-Y-N-G-N-E-D-R-G-L-I-L-L-E-L-A-G-T-F-Q-L-A-T-K-K-A-H-A-E-F-L-R-K-L-V-E-V-P-S-N-T-V-L-S-Q-A-S-L-E-T-L-A-I-I-A-Y-R-Q-P-V-T-R-M-E-V-D-E-V-R-G-V-Q-T-D-G-P-I-R-T-L-V-A-K-G-L-V-T-D-K-G-R-V-D-G-A-G-R-A-K-L-Y-V-T-T-S-E-F-L-D-A-F-G-L-N-S-L-D-D-L-P-K-L-A-D-P-E-A-E-D-P-D-Q-S-E-M-D-L-F-F-D-R-F-N-Q-S-K-E-Q-E-E-E"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-H-I-A-L-I-A-H-D-E-K-K-D-L-M-V-G-F-A-T-A-Y-K-H-L-L-E-P-H-Q-L-Y-A-T-G-T-T-G-L-R-I-I-E-A-T-G-L-T-V-H-R-F-K-S-G-P-L-G-G-D-Q-Q-I-G-A-R-I-S-E-N-K-M-D-L-V-I-F-L-R-D-P-L-T-A-Q-P-H-E-P-D-V-S-A-L-I-R-L-C-D-V-Y-E-I-P-L-A-T-N-I-G-T-A-E-I-L-I-R-G-L-G-A-G-F-L-D-W-R-D-L-R-R-N-D-E"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-T-S-E-Q-F-E-Y-H-L-T-G-K-E-I-L-E-K-E-F-K-T-G-L-R-G-Y-N-P-E-D-V-D-E-F-L-D-M-V-I-K-D-Y-S-T-F-T-Q-E-I-E-A-L-Q-A-E-N-I-R-L-V-Q-E-L-D-N-A-P-V-R-T-T-T-Q-P-A-P-T-F-Q-A-A-A-Q-P-A-G-T-T-N-F-D-I-L-K-R-L-S-N-L-E-K-H-V-F-G-N-K-L-D-D-N-E"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-V-A-K-H-E-H-Q-Q-A-L-V-E-Q-Y-A-E-L-R-R-T-L-K-A-E-G-R-F-D-E-L-R-K-L-P-R-D-S-S-P-T-R-L-H-N-R-C-E-L-T-G-R-P-H-G-Y-M-R-K-F-G-M-S-R-I-R-F-R-E-L-A-H-Q-G-Q-L-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-T-K-E-S-L-E-K-A-T-F-A-G-G-C-F-W-C-M-V-K-P-F-D-T-Q-P-G-I-E-K-V-V-S-G-Y-T-G-G-H-T-V-N-P-T-Y-K-E-V-C-S-G-T-T-G-H-T-E-A-V-E-I-T-F-D-P-A-V-F-P-Y-E-K-L-V-E-V-Y-W-Q-Q-T-D-P-T-D-A-A-G-Q-F-V-D-R-G-D-S-Y-R-P-V-I-F-Y-H-N-E-E-Q-R-Q-I-A-E-K-S-K-A-A-L-D-A-S-G-R-F-K-K-P-V-V-T-E-I-A-K-A-E-T-F-Y-P-A-E-E-Y-H-Q-D-F-Y-K-K-E-K-A-H-Y-E-G-Y-Q-V-A-S-G-R-A-A-F-I-D-A-N-W-K-G"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-Q-K-Q-V-V-V-M-D-E-A-A-I-K-R-A-L-T-R-V-S-Y-E-I-I-E-R-N-K-G-T-K-N-L-A-L-V-G-I-K-T-R-G-I-Y-L-A-E-R-L-H-K-R-I-L-E-I-E-G-I-D-V-P-V-G-D-I-D-I-T-L-Y-R-D-D-L-S-F-K-D-D-K-T-R-E-P-A-V-H-G-T-N-I-P-F-D-I-N-G-K-K-V-V-L-V-D-D-V-L-Y-T-G-R-T-V-R-A-A-M-D-A-L-M-D-V-G-R-P-A-Q-I-H-L-A-V-L-A-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-G-N-E-R-V-E-V-R-L-T-D-V-D-H-S-E-D-A-V-I-I-N-K-N-E"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-L-Y-P-S-I-D-N-L-L-L-K-I-D-S-K-Y-S-L-V-T-V-A-A-K-R-A-R-Y-M-Q-L-E-N-D-K-G-V-L-P-S-Y-Q-S-D-K-F-V-G-K-A-L-E-E-I-H-A-G-K-L-V-L-Q-N-D-E-K"} +{"text": "### FUNCTION Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism ### SEQUENCE -M-K-K-Y-S-K-K-D-R-Q-M-K-L-Q-V-A-I-E-E-N-P-F-I-T-D-E-Q-L-A-E-K-F-G-V-I-V-Q-T-I-R-L-D-R-V-A-L-S-I-P-E-L-R-E-R-I-K-H-V-A-S-V-N-Y-A-D-A-V-K-S-L-P-I-D-E-V-I-G-E-I-I-D-I-Q-L-S-K-S-A-I-S-I-F-D-V-R-S-E-H-V-F-K-R-N-K-I-A-R-G-H-H-L-F-A-Q-A-N-S-L-A-T-A-V-I-P-N-E-L-A-L-T-T-Q-A-T-V-R-F-V-R-S-V-Y-E-G-E-R-I-I-A-K-A-K-V-R-P-A-T-D-N-R-A-I-T-I-V-D-V-K-S-Y-V-G-D-E-I-V-L-K-G-K-F-E-M-Y-H-A-T-Q-K"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-K-M-Y-N-V-G-K-I-V-N-T-H-G-L-I-G-E-I-R-V-I-A-T-T-D-F-P-E-E-R-F-Q-V-G-N-T-V-Y-L-F-E-K-N-S-K-K-P-E-K-L-I-I-R-S-H-R-K-H-K-N-F-D-L-L-M-F-E-G-L-T-G-I-H-Q-V-E-R-M-K-E-G-V-L-K-I-K-E-A-Q-L-T-D-L-E-E-N-E-F-Y-F-H-E-I-I-G-C-T-V-V-T-T-D-G-E-E-L-G-E-I-T-E-I-L-T-P-G-A-N-D-V-W-V-V-K-G-A-D-K-K-E-K-L-I-P-Y-I-A-D-V-V-K-D-I-N-T-N-D-K-K-I-T-I-E-V-M-E-G-L-L-D"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-K-L-I-D-E-I-T-K-S-Q-L-N-P-D-V-P-S-F-R-P-G-D-T-V-R-V-H-A-K-V-V-E-G-T-R-E-R-I-Q-L-F-E-G-V-V-I-K-R-R-G-A-G-I-S-E-T-F-T-V-R-K-I-S-N-G-V-G-V-E-R-T-F-P-V-H-T-P-R-I-A-K-L-E-V-I-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-N-L-R-G-K-A-A-R-I-K-E-I-R"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-N-I-S-K-E-T-V-E-K-V-A-N-L-A-K-L-E-V-S-E-T-E-A-T-A-F-A-G-Q-L-G-K-I-I-E-L-V-E-Q-L-N-T-L-D-T-N-N-V-E-P-T-S-H-A-I-D-V-S-N-V-L-R-E-D-V-A-T-K-G-L-D-R-K-E-V-L-K-N-A-P-D-Q-Q-D-G-M-F-K-V-P-T-I-M-E-Q"} +{"text": "### FUNCTION Catalyzes the hydration of fosfomycin ### SEQUENCE -M-I-S-G-L-S-H-I-T-L-I-V-K-D-L-N-K-T-T-T-F-L-E-E-I-F-D-A-E-E-I-Y-S-S-G-D-D-T-F-S-L-S-K-E-K-F-F-L-I-A-G-L-W-I-C-I-M-E-G-E-S-L-Q-E-R-T-Y-N-H-I-A-F-Q-I-Q-A-E-E-M-D-E-Y-I-E-R-I-K-S-L-G-M-E-I-K-P-E-R-S-R-V-K-G-E-G-R-S-V-Y-F-Y-D-Y-D-N-H-L-F-E-L-H-A-G-T-L-E-E-R-L-K-R-Y-H-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-M-L-I-G-G-I-R-L-Y-Q-K-Y-I-S-R-F-T-P-A-T-C-R-F-Y-P-T-C-S-A-Y-G-I-E-A-I-E-T-H-G-A-L-K-G-S-Y-L-A-I-R-R-I-S-K-C-H-P-F-H-K-G-G-L-D-F-V-P-P-K-K-D-K-N-D-D-S-G-H-T-C-K-A-H-H-H-H"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-R-Y-T-G-P-S-W-K-V-S-R-R-L-G-I-S-L-S-G-T-G-K-E-L-E-R-R-P-Y-A-P-G-Q-H-G-P-T-Q-R-K-K-I-S-E-Y-G-L-Q-Q-A-E-K-Q-K-L-R-H-M-Y-G-L-T-E-R-Q-F-K-N-T-F-N-K-A-G-K-L-Q-G-K-H-G-E-N-F-M-I-L-L-E-Q-R-L-D-N-I-V-Y-R-L-G-L-A-R-T-R-R-A-A-R-Q-L-V-N-H-G-H-I-T-V-D-G-K-R-V-D-I-P-S-Y-Q-V-S-V-G-Q-V-I-S-V-R-E-K-S-A-K-N-S-A-I-A-E-S-L-E-V-S-S-F-V-P-E-Y-V-T-F-D-A-E-T-L-T-G-S-L-N-R-L-P-E-R-S-E-L-A-A-E-I-N-E-A-F-I-V-E-F-Y-S-R"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-T-C-K-Y-N-G-T-R-V-V-D-S-R-P-A-D-D-G-N-S-I-R-R-R-R-E-C-E-K-C-G-F-R-F-T-T-F-E-K-V-E-E-S-P-L-I-V-V-K-K-D-G-A-R-E-E-F-A-R-E-K-V-R-R-G-L-I-R-A-C-E-K-R-P-V-S-A-E-Q-I-E-E-I-V-N-E-V-E-R-E-L-R-N-I-G-D-S-E-I-A-S-D-L-I-G-E-K-V-M-N-K-L-A-S-L-D-E-V-A-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-I-S-V-F-V-E-E-L-K-D-L-M-E-K-N-K-D-R"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-D-V-N-N-V-E-L-V-I-S-A-V-R-P-E-Q-Y-P-E-T-D-L-P-E-Y-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-M-I-R-R-K-S-M-A-R-I-S-Q-K-P-G-K-T-Q-T-L-N-F-Y-K-I-E-E-A-L-F-F-V-D-V-P-G-Y-G-F-A-K-V-S-K-T-E-R-E-K-W-G-V-M-I-E-T-Y-I-T-S-R-E-Q-L-R-G-V-I-Q-I-V-D-L-R-H-K-P-T-E-D-D-R-M-M-Y-E-F-L-K-Y-Y-D-I-P-V-I-V-V-A-T-K-A-D-K-I-P-R-S-K-W-Q-K-N-A-K-I-V-R-E-T-L-D-F-D-P-D-D-K-F-V-L-F-S-S-E-T-K-M-G-K-D-E-A-W-Q-F-I-K-E-G-M-E"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-E-T-G-G-K-Q-I-K-V-E-A-G-Q-E-I-Y-V-E-K-L-A-G-E-V-G-D-V-V-T-F-D-K-V-L-F-V-G-G-D-S-A-K-V-G-V-P-F-V-D-G-A-T-V-T-A-K-V-E-K-Q-G-R-A-K-K-L-T-V-Y-K-Y-K-P-K-K-N-Y-H-K-K-Q-G-H-R-Q-P-Y-T-K-L-T-I-D-A-I-N-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-M-G-L-D-V-G-S-K-T-V-G-V-A-I-S-D-P-L-G-W-T-A-Q-G-V-E-T-I-Q-I-D-E-S-R-K-Q-F-G-Y-D-R-V-K-E-L-V-L-E-Y-E-V-E-K-V-V-V-G-L-P-K-N-M-N-N-T-I-G-P-R-A-E-S-S-K-I-Y-A-E-V-L-E-S-R-I-G-L-P-V-V-L-W-D-E-R-L-T-T-S-A-A-E-R-T-L-I-E-A-D-V-S-R-K-K-R-K-E-V-I-D-K-L-A-A-V-M-I-L-Q-S-Y-L-D-T-T-N"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-K-H-K-V-G-I-L-G-G-T-F-D-P-P-H-L-A-H-L-H-M-A-E-E-A-K-A-Q-L-G-L-E-K-I-L-F-L-P-N-K-V-P-P-H-K-Q-I-S-G-M-A-S-N-E-E-R-V-E-M-L-Q-L-M-I-E-D-R-D-S-F-E-I-D-T-R-E-L-M-R-T-G-K-S-Y-T-Y-D-T-M-R-D-M-I-S-E-Q-P-N-T-D-F-Y-F-I-I-G-G-D-M-V-E-Y-L-P-K-W-Y-H-I-D-D-L-V-K-M-V-T-F-V-G-V-N-R-P-L-Y-Q-K-E-V-P-Y-D-I-V-K-I-N-M-P-E-T-A-I-S-S-T-E-I-R-N-D-I-E-H-A-E-A-F-L-P-E-K-V-W-S-Y-I-K-E-H-Q-L-Y-G-K-K"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-E-K-K-N-K-K-E-K-L-A-E-E-I-E-Q-E-E-L-N-S-L-D-E-S-V-E-T-V-E-E-E-A-T-E-E-T-L-T-E-E-Q-A-K-I-L-E-L-E-N-K-L-D-E-V-E-N-R-Y-L-R-M-Q-A-D-F-E-N-V-K-K-R-H-I-A-D-R-D-A-S-Q-K-Y-R-S-Q-S-L-A-Q-D-L-L-P-A-L-D-S-F-E-K-A-L-A-T-T-S-D-Q-E-E-V-K-Q-I-L-K-G-M-E-M-V-Y-N-Q-I-L-V-A-F-E-K-E-G-I-E-V-I-P-A-V-G-E-Q-F-D-P-N-F-H-Q-A-V-M-Q-D-S-D-E-N-A-G-S-N-E-I-T-A-E-L-Q-K-G-Y-K-L-K-D-R-V-I-R-P-S-M-V-K-V-N-Q"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-V-L-E-I-D-L-L-D-E-T-N-N-L-P-D-E-D-K-Q-L-V-E-N-I-L-Q-F-A-A-G-Y-L-K-I-E-E-G-T-E-L-S-L-T-F-T-T-N-E-G-I-Q-E-I-N-R-E-Y-R-N-K-D-Q-A-T-D-V-I-S-F-A-L-E-E-M-G-D-G-E-T-E-I-D-W-G-D-F-D-L-E-T-P-R-M-L-G-D-I-I-I-S-T-E-K-A-E-E-Q-A-K-D-Y-G-H-T-K-A-R-E-L-G-F-L-A-V-H-G-L-L-H-L-L-G-Y-D-H-M-E-P-D-E-E-K-V-M-F-G-L-Q-K-E-V-L-D-A-Y-G-L-E-R"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-G-H-R-H-I-I-I-R-E-L-I-T-S-N-E-I-D-T-Q-E-D-L-V-E-L-L-L-E-R-D-V-K-V-T-Q-A-T-V-S-R-D-I-K-E-L-H-L-V-K-V-P-T-Q-T-G-G-Y-K-Y-S-L-P-A-D-N-S-F-N-P-H-Q-K-L-K-R-A-L-I-D-C-F-I-C-I-D-T-V-Q-F-M-I-I-L-K-V-M-P-G-N-G-N-S-V-G-A-L-I-D-N-L-D-W-P-E-K-A-G-T-L-C-G-D-D-T-C-L-I-I-C-R-S-E-E-N-A-K-T-L-T-D-R-F-I-D-M-L"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-T-K-K-K-T-F-E-E-A-I-A-E-L-E-T-I-V-E-A-L-E-N-G-S-A-S-L-E-D-S-L-D-M-Y-Q-K-G-I-E-L-T-K-L-C-Q-D-K-L-Q-S-A-E-Q-R-M-A-K-V-V-T-E-A-G-E-E-I-P-F-E-A-D-G-E"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-R-R-E-A-R-E-K-A-L-Q-A-L-F-Q-I-E-L-N-E-M-S-L-D-Q-A-I-K-N-I-M-E-D-E-Q-D-D-Y-M-E-Q-L-V-E-G-V-M-A-N-K-A-E-I-D-A-I-I-E-P-N-L-D-N-W-R-I-D-R-L-N-K-V-D-L-S-L-L-R-L-S-V-Y-E-I-K-Y-L-D-D-V-P-N-R-V-S-L-N-E-S-I-E-I-A-K-I-Y-S-D-E-K-S-S-K-F-I-N-G-V-L-A-N-I-A-P-E-D-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-Q-E-R-K-N-E-I-I-A-E-Y-R-V-H-D-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-A-E-I-N-S-L-N-E-H-V-R-V-H-K-K-D-H-H-S-Y-R-G-L-M-K-M-V-G-H-R-R-N-L-L-T-Y-L-R-K-K-D-V-Q-R-Y-R-E-L-I-K-R-L-G-L-R-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-N-V-R-A-N-R-V-S-E-Q-M-K-K-E-L-G-D-I-L-N-R-K-I-K-D-P-R-L-G-F-V-T-V-T-G-V-D-V-T-G-D-L-Q-E-A-K-V-F-I-S-I-L-G-T-D-K-E-K-E-N-T-L-L-A-L-E-K-A-H-G-F-I-R-S-E-I-G-R-R-I-R-L-R-K-V-P-E-M-S-F-E-I-D-N-S-I-A-Y-G-N-R-I-D-E-L-L-R-D-L-N-N-D-Q"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-K-V-L-E-Q-V-E-A-I-V-A-P-I-T-D-E-L-Q-L-E-L-V-D-I-A-F-E-K-E-G-P-N-W-F-L-R-I-F-I-D-K-D-G-G-V-D-I-D-E-C-A-A-V-S-E-K-V-S-E-K-M-D-E-S-D-P-I-T-Q-N-Y-F-L-E-V-S-S-P-G-A-E-R-P-L-K-K-E-Q-D-F-E-N-A-V-G-K-Y-V-H-V-T-S-Y-E-P-I-D-G-R-K-M-W-E-G-T-L-V-S-Y-D-G-T-T-L-V-I-T-I-T-D-K-T-R-K-I-T-C-E-I-P-K-D-K-V-A-K-A-R-L-A-I-Q-F"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-K-E-V-L-S-K-S-K-E-K-M-E-K-A-E-Q-A-L-T-R-Q-L-G-T-I-R-A-G-R-A-N-A-S-L-L-D-R-L-T-V-D-Y-Y-G-A-A-T-P-V-N-Q-M-A-S-I-S-V-P-E-A-R-M-L-L-I-T-P-Y-D-K-T-I-L-G-E-I-E-K-A-I-L-K-S-D-L-G-L-T-P-N-N-D-G-S-V-L-R-L-S-I-P-Q-L-T-E-E-R-R-K-E-L-V-K-E-V-K-K-E-A-E-E-A-K-V-A-V-R-N-I-R-R-E-A-N-E-D-L-K-K-L-E-K-N-G-D-I-T-E-D-D-L-R-S-Y-G-E-D-V-Q-K-L-T-D-E-S-I-K-N-I-D-S-I-T-K-D-K-E-A-E-I-L-E-V"} +{"text": "### FUNCTION Inhibits cell division during the SOS response Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and/or DivIC to the division machinery ### SEQUENCE -M-T-L-K-L-I-W-D-K-F-Y-V-S-I-I-F-V-I-T-C-L-V-L-G-I-I-L-M-C-T-V-I-G-S-G-S-E-Y-S-E-V-D-V-N-E-G-D-S-I-W-A-L-A-D-Q-Y-A-A-K-S-D-M-A-K-A-D-F-V-S-W-V-E-K-E-N-N-L-T-D-G-H-V-K-A-G-D-Y-V-V-I-P-V-H-E-T-K-L-Q-R-S-D-S-T-I-Q-L-A-N-Q"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-A-E-K-M-N-V-E-S-F-N-L-D-H-T-K-V-K-A-P-F-V-R-L-A-G-T-K-V-G-V-H-G-D-E-I-Y-K-Y-D-V-R-F-K-Q-P-N-K-E-H-M-E-M-P-A-L-H-S-L-E-H-L-M-A-E-L-A-R-N-H-T-D-K-L-V-D-I-S-P-M-G-C-Q-T-G-F-Y-M-S-F-I-N-H-N-D-Y-D-D-A-L-E-I-L-A-T-T-L-T-D-V-L-A-A-D-S-V-P-A-C-N-E-V-Q-C-G-W-A-A-S-H-S-L-E-G-A-K-E-L-A-E-E-F-L-A-K-R-S-E-W-K-N-V-F-G-E"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-L-T-M-D-D-I-V-R-E-G-H-P-A-L-R-E-V-A-T-E-V-T-F-P-L-S-D-E-E-K-K-L-G-H-D-M-L-E-F-L-I-N-S-Q-D-E-E-L-A-E-K-Y-G-L-R-G-G-V-G-I-A-A-P-Q-L-A-V-T-K-R-F-L-A-I-H-V-H-D-E-K-D-R-L-Y-S-Y-V-L-Y-N-P-K-I-R-S-H-S-V-Q-Q-A-C-L-S-G-G-E-G-C-L-S-V-D-R-E-V-P-G-Y-V-V-R-S-E-R-V-T-I-D-A-F-D-E-N-G-T-P-L-K-L-R-F-K-G-Y-P-A-I-V-V-Q-H-E-I-D-H-L-N-G-V-M-F-Y-D-H-I-N-K-E-N-P-S-Y-L-P-P-D-V-D-V-F-G"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-F-K-V-F-Y-Q-E-T-L-T-E-T-P-V-R-E-K-T-Q-S-L-Y-V-E-A-E-S-E-V-K-V-R-Q-L-L-K-D-E-P-F-H-I-E-F-V-E-K-I-S-D-A-H-L-A-Y-E-K-E-N-P-D-F-A-L-W-E-K"} +{"text": "### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-A-F-R-E-N-V-L-E-I-L-E-E-I-T-E-T-D-E-V-V-Q-N-T-N-I-K-L-F-D-E-G-L-L-D-S-M-A-T-V-Q-L-L-I-E-I-E-S-R-L-D-I-T-V-P-V-S-E-F-D-R-D-E-W-A-T-P-E-M-I-I-T-Q-L-E-A-L-K"} +{"text": "### FUNCTION Negative regulator of sigma-B activity Phosphorylates and inactivates its specific antagonist protein, RsbV Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme ### SEQUENCE -M-A-T-M-H-D-K-I-T-L-Q-L-P-A-K-P-E-Y-V-S-L-G-R-L-S-L-S-G-I-A-S-R-A-G-F-S-Y-E-A-I-E-D-L-K-I-A-V-S-E-A-I-T-N-S-V-K-H-A-F-K-G-E-E-D-G-E-I-T-V-E-Y-H-I-Y-E-D-K-L-E-V-R-V-S-D-N-G-T-S-F-D-L-E-T-R-K-Q-E-I-G-P-Y-E-V-G-E-D-A-E-M-M-R-I-G-G-L-G-L-F-L-I-E-T-L-M-D-D-V-K-L-Y-Y-D-E-G-V-S-V-V-M-T-K-Y-I-N-E-K-Q-V-E-E-N-A-K-S-I-S-T"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-K-G-I-G-L-D-M-I-D-L-D-R-V-K-Q-A-V-E-K-N-P-R-F-I-E-R-I-L-T-E-K-E-T-K-Q-Y-E-K-Y-E-G-S-R-K-I-E-F-L-A-G-R-F-A-A-K-E-A-Y-A-K-A-N-G-T-G-F-G-K-H-L-S-F-T-D-V-E-I-L-Q-V-E-D-G-R-P-H-V-T-M-P-I-K-Q-G-E-T-V-F-V-S-I-T-H-T-A-R-S-A-A-A-Q-V-I-I-E-Q"} +{"text": "### FUNCTION Could be involved in the glycerol uptake either via facilitated diffusion or active transport ### SEQUENCE -M-K-F-F-R-G-M-I-G-F-C-I-A-G-M-I-V-M-S-V-W-T-P-L-A-E-N-Y-G-I-F-G-G-Y-L-A-A-F-I-I-I-G-P-M-W-F-M-N-H-H-V-G-L-I-E-N-D-E-D-A-A-F-V-D-M-A-V-G-I-G-I-C-G-I-M-R-D-V-F-M-R-G-G-G-E-L-V-S-S-L-P-T-I-G-L-V-A-I-G-A-V-L-A-G-I-V-A-A-A-I-E-K-D-M-A-R-K-H-E-A-K-Q-E-K-T-E-P-G-M-N-I-K-E-E-E-R-L-N-E-N-Q-L-V"} +{"text": "### FUNCTION Could be involved in the glycerol uptake either via facilitated diffusion or active transport ### SEQUENCE -M-S-I-G-I-A-L-A-T-I-A-G-G-F-L-F-P-F-A-I-R-M-M-W-G-K-M-V-D-E-W-G-A-I-G-G-W-M-A-A-A-F-I-V-G-T-V-W-T-I-N-H-G-I-P-K-S-M-I-Y-Q-S-G-T-V-W-V-D-M-A-V-A-A-G-I-G-V-F-T-A-S-L-L-T-G-G-K-F-S-K-S-V-V-N-L-A-A-A-V-V-G-G-V-L-G-G-F-L-L-S-L-F-L"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-N-I-Q-I-V-T-V-G-K-L-K-E-K-Y-L-V-Q-G-I-A-E-Y-L-K-R-L-S-A-Y-A-K-V-S-I-V-E-V-P-D-E-K-A-P-E-V-L-S-D-A-E-M-K-Q-V-K-D-K-E-G-V-R-I-L-A-K-I-P-D-D-A-H-V-I-A-L-A-I-D-G-K-M-K-S-S-E-E-F-A-A-D-L-D-K-L-A-T-Y-G-K-S-K-V-A-F-V-I-G-G-S-L-G-L-S-E-A-V-L-K-R-S-N-E-Q-I-S-F-G-R-L-T-L-P-H-Q-L-M-R-L-V-L-V-E-Q-V-Y-R-A-F-R-I-V-R-G-E-P-Y-H-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-N-I-E-E-I-I-A-S-V-K-E-A-S-V-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-V-A-A-A-G-G-G-A-A-E-Q-T-E-F-T-V-E-L-A-S-A-G-D-S-K-I-K-V-I-K-V-V-R-E-I-T-G-L-G-L-K-E-A-K-E-L-V-D-N-A-P-K-A-L-K-E-G-V-A-K-D-E-A-E-E-I-K-A-K-L-E-E-V-G-A-N-V-E-V-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-A-G-L-G-N-P-G-K-K-Y-E-R-T-R-H-N-V-G-F-M-V-V-D-E-L-S-F-R-H-Q-T-P-W-K-K-S-K-F-N-G-M-V-S-E-I-N-V-G-G-E-K-M-I-L-V-K-P-L-T-F-M-N-A-S-G-E-C-I-R-P-L-M-D-Y-Y-N-I-Q-I-E-D-V-L-I-V-Y-D-D-L-D-L-P-V-G-K-I-R-L-R-Q-K-G-S-A-G-G-H-N-G-M-K-S-I-I-Q-H-V-K-T-Q-E-F-N-R-I-R-V-G-V-S-R-P-L-K-G-E-V-I-H-Y-V-L-G-D-F-P-K-A-E-Q-P-D-I-I-A-A-I-Q-K-S-A-D-A-I-E-D-F-A-Q-T-P-F-I-E-V-M-N-K-Y-N"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-V-T-D-V-R-L-R-R-V-E-T-D-G-R-M-R-A-I-A-S-I-T-L-D-E-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-G-V-D-G-E-F-R-D-I-A-H-P-I-N-S-D-T-R-A-K-I-Q-E-V-V-L-A-E-Y-E-R-V-G-E-E-E-A-T-A-V-T-E-E-E-S-E-S-V-S-A-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-K-D-V-K-G-K-G-K-K-G-E-T-K-N-V-A-D-G-Y-A-N-N-F-L-I-K-N-G-Y-A-V-E-A-S-N-A-A-L-S-T-L-S-A-Q-K-K-K-E-D-K-L-A-A-E-E-L-A-E-A-K-A-L-K-E-K-M-E-K-L-T-V-E-L-K-A-K-S-G-E-G-G-R-L-F-G-S-I-T-S-K-Q-I-A-Q-T-L-E-K-T-H-G-I-K-V-D-K-R-K-M-D-L-P-E-A-I-R-A-L-G-H-T-K-V-P-V-K-L-H-H-E-V-T-A-T-L-D-V-H-V-S-E-E"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-M-N-R-V-V-L-V-G-R-L-T-K-D-P-E-L-R-Y-T-P-A-G-V-A-V-A-T-F-T-L-A-V-N-R-T-F-T-N-Q-Q-G-E-R-E-A-D-F-I-N-C-V-V-W-R-K-P-A-E-N-V-A-N-F-L-K-K-G-S-M-A-G-V-D-G-R-V-Q-T-R-N-Y-E-G-N-D-G-K-R-V-Y-V-T-E-I-V-A-E-S-V-Q-F-L-E-P-R-N-S-N-G-G-G-G-N-N-N-Y-Q-G-G-N-N-N-N-N-Y-N-N-G-G-N-N-F-G-Q-A-P-T-N-N-G-G-F-G-Q-D-Q-Q-Q-S-Q-N-Q-N-Y-Q-S-T-N-N-D-P-F-A-S-D-G-K-P-I-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-R-K-Y-E-I-M-Y-I-I-R-P-N-I-E-E-D-E-K-K-A-V-V-E-R-F-D-G-I-L-T-E-N-G-A-E-I-I-E-S-K-E-W-G-K-R-R-L-A-Y-E-I-N-D-Y-R-D-G-F-Y-H-I-V-K-L-N-A-D-K-A-D-S-I-N-E-F-D-R-L-A-K-I-S-D-D-I-V-R-H-M-V-I-K-E-E-A"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-V-N-F-N-Q-F-L-K-Q-A-Q-S-M-Q-K-K-M-Q-E-A-Q-E-Q-M-A-N-A-R-Y-T-G-K-A-G-G-G-L-V-E-V-I-A-T-G-K-G-E-V-E-K-I-S-I-D-E-S-L-L-K-A-E-E-K-E-M-L-E-D-L-I-K-V-A-F-N-D-A-Q-Q-K-C-D-E-D-S-Q-N-S-L-S-G-A-L-N-G-M-R-L-P-P-G-F-K-M-P-F"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-N-T-K-F-P-I-T-A-K-G-F-E-K-L-E-H-E-L-K-H-L-K-H-V-E-R-K-K-I-S-A-D-I-A-E-A-R-E-H-G-D-L-S-E-N-A-E-Y-E-A-A-R-E-K-Q-A-F-I-E-G-R-I-K-E-L-E-D-M-T-A-R-A-E-I-I-D-I-G-K-L-S-G-D-N-I-K-F-G-A-T-V-T-L-I-D-D-D-T-E-E-E-V-T-Y-I-I-V-G-E-Y-E-A-D-I-T-R-K-R-V-S-I-A-S-P-I-A-K-A-L-I-G-K-S-V-G-D-F-V-E-V-T-T-P-K-G-S-K-S-Y-E-V-V-T-V-E-Y-K-E-L-E-L"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-L-N-K-V-I-L-I-G-N-V-G-R-D-P-E-M-R-T-T-G-E-G-K-K-I-I-N-L-S-L-A-T-T-E-T-W-K-D-R-I-T-S-E-R-K-E-R-T-E-W-H-R-V-V-I-F-S-E-G-L-V-S-V-V-E-R-Y-V-T-K-G-S-K-L-Y-I-E-G-S-L-Q-T-R-K-W-N-D-N-S-G-Q-E-K-Y-T-T-E-V-V-L-Q-N-F-N-S-Q-L-I-L-L-D-S-K-N-S-N-N-H-N-Q-D-S-G-H-S-E-Y-K-H-P-E-T-K-N-H-S-F-D-H-S-D-L-D-D-E-I-P-F"} +{"text": "### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-T-Y-V-V-T-D-E-C-V-K-C-K-Y-T-D-C-V-E-V-C-P-V-D-C-F-Y-E-G-E-R-E-D-D-F-M-L-V-I-N-P-D-E-C-I-D-C-G-V-C-V-P-D-C-P-I-G-A-I-K-P-E-S-P-G-L-I-E-W-V-E-R-A-K-D-F-I-E-N-K-G-W-K-N-I-T-K-K-K-T-A-L-P-D-A-D-K-F-K-D-E-K-D-K-F-N-K-Y-I-G-S-V-K-I-A-N"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-L-I-Q-F-T-G-T-V-L-E-L-L-P-N-A-T-F-R-V-K-L-E-N-D-H-V-I-I-A-H-T-S-G-R-M-R-K-N-R-I-R-I-L-L-G-D-K-V-M-V-E-M-T-P-Y-D-L-T-K-G-R-V-I-H-R-H"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-K-G-N-L-I-K-N-Y-A-V-A-L-L-N-N-A-M-V-D-N-I-Q-D-K-I-F-E-E-I-T-S-I-N-R-I-I-T-D-N-F-D-I-R-E-F-L-F-S-P-I-V-N-K-N-D-K-I-N-A-V-N-S-L-A-K-N-I-K-I-S-T-I-V-Q-N-F-L-L-L-L-V-K-N-S-R-T-A-I-L-S-N-I-V-D-A-Y-N-T-L-L-Y-E-S-K-N-I-K-I-V-Q-V-I-S-A-N-K-L-Q-P-K-E-Q-E-W-I-K-S-R-I-E-K-E-L-N-Q-T-T-E-I-L-F-D-I-D-N-T-I-I-G-G-I-I-I-K-Y-D-S-M-L-Q-D-Y-S-I-K-G-S-L-E-K-I-K-K-A-L-K-I-V-N-I-A-V"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-N-A-T-I-L-V-K-I-I-T-P-L-S-I-A-L-E-K-Q-A-K-M-V-T-M-S-G-E-E-G-M-F-G-V-L-P-S-H-V-P-M-I-V-S-L-K-A-G-L-V-Q-V-Y-I-D-D-M-H-K-S-E-N-T-Y-L-I-S-G-G-V-T-E-V-T-A-N-Y-I-N-I-A-T-E-T-A-I-N-V-T-N-L-S-E-V-E-I-A-T-K-L-L-D-L-Q-K-T-L-S-D-Q-H"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-E-F-K-I-M-S-T-T-D-K-I-E-Q-K-V-I-E-M-V-A-E-K-L-N-K-D-K-S-I-I-T-T-D-S-R-F-I-E-D-L-K-A-D-S-L-D-T-V-E-L-M-M-A-I-E-V-E-Y-G-I-D-I-P-D-D-E-A-T-K-I-K-T-V-S-D-V-I-K-Y-I-K-E-R-Q-S"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-I-K-A-G-G-K-Q-Y-K-V-D-R-N-S-I-I-K-V-E-K-I-D-G-E-L-G-S-K-I-Q-F-D-Q-I-L-M-I-G-E-Y-S-K-P-S-F-I-G-T-P-I-V-K-G-A-V-V-T-A-E-I-T-N-Q-L-K-D-N-K-I-I-V-F-K-K-K-R-R-K-N-Y-R-R-K-A-G-H-R-Q-E-L-T-E-L-K-I-L-D-I-T-K-Q"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-M-S-L-S-H-L-L-I-V-L-L-I-I-F-V-L-F-G-A-G-K-L-P-Q-V-M-S-D-L-A-K-G-L-K-A-F-K-D-G-M-K-D-D-G-S-D-N-D-K-N-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-N-V-E-I-V-R-N-Y-N-K-W-R-E-H-K-Q-I-N-K-S-L-I-K-K-I-T-Q-N-I-L-L-R-F-D-N-F-S-K-I-K-Q-F-E-L-S-I-L-L-T-N-A-A-E-I-L-T-L-N-K-Q-F-R-N-I-E-K-A-T-N-V-L-S-F-P-S-N-E-L-N-W-Q-D-L-Y-S-K-L-E-F-L-G-D-S-D-Y-M-H-L-G-D-I-A-F-C-Y-E-V-I-Y-N-E-S-C-E-Q-H-K-T-F-E-N-H-F-I-H-L-L-I-H-S-I-L-H-L-I-G-F-D-H-Q-N-D-T-E-A-N-I-M-E-N-L-E-I-E-I-L-S-Y-F-G-I-F-P-P-Y"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-N-K-I-K-I-R-L-K-S-F-D-H-R-S-L-D-Q-A-T-K-E-I-V-S-A-V-K-R-T-F-A-N-I-N-G-P-I-P-L-P-K-K-I-G-R-F-T-V-N-R-S-P-H-V-H-K-K-S-R-E-Q-F-E-I-R-K-H-K-R-L-L-V-I-G-D-P-N-P-A-V-V-D-A-L-S-K-V-D-L-A-A-G-V-D-V-V-I-E-L-E-S-G-E"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-S-Y-K-Y-Y-D-L-I-R-K-P-I-I-T-E-K-T-T-T-L-S-E-Q-N-K-Y-A-F-Y-V-D-K-F-A-K-K-L-T-L-K-K-A-I-E-E-I-F-K-V-K-V-K-K-V-N-I-L-N-V-K-G-K-K-K-R-F-K-G-I-I-G-T-Q-I-N-R-K-K-A-I-V-T-L-E-K-D-H-N-I-D-F-A-G-G-I-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-I-W-K-G-P-F-V-D-G-Y-L-I-K-K-V-Q-K-L-M-E-S-G-K-S-E-M-I-K-T-W-S-R-R-S-T-I-L-P-I-F-V-G-F-T-F-S-V-H-N-G-N-K-F-I-P-V-S-V-N-E-E-M-V-G-R-K-L-G-E-F-A-P-T-R-T-F-H-G-H-G-A-D-K-K-I-K-R-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-V-Q-E-N-K-N-F-A-T-A-Q-A-K-S-I-R-V-S-S-R-K-L-N-L-V-A-A-F-I-R-N-M-K-V-S-E-A-L-V-Q-L-T-F-S-P-K-R-I-A-K-V-V-K-D-C-L-Q-S-A-V-A-N-A-E-N-N-L-G-L-D-I-D-R-L-V-V-T-K-A-T-V-G-K-A-L-V-M-K-R-V-M-P-R-A-K-G-R-A-T-R-I-N-K-F-F-S-N-L-Y-I-T-V-T-E-K-E-D-N"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-A-P-K-K-Q-K-F-R-K-A-H-K-G-R-V-A-S-T-A-K-A-G-T-T-L-A-F-G-S-F-G-L-K-S-I-D-G-W-R-V-T-A-R-Q-I-E-A-G-R-K-A-A-T-R-C-M-K-R-Q-G-R-L-W-I-R-I-F-P-D-V-P-V-S-K-K-P-A-E-V-R-M-G-K-G-K-G-S-P-E-F-F-A-V-R-V-S-P-G-R-I-M-F-E-I-E-G-V-E-E-N-V-A-L-R-A-L-E-L-A-S-A-K-L-P-V-R-T-R-I-V-R-R-Y-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-V-L-Q-G-V-V-I-S-S-K-A-D-K-T-V-T-V-K-V-E-R-K-F-K-H-P-I-Y-K-K-F-V-K-V-S-K-K-Y-A-A-H-D-S-E-N-K-Y-Q-E-G-D-K-V-S-I-I-E-S-R-P-I-S-K-T-K-T-W-V-V-V-N-G-E"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-I-L-E-V-A-D-N-S-G-A-K-K-V-M-C-I-K-V-L-G-G-S-H-H-M-V-A-K-L-G-D-V-I-V-V-S-V-K-D-A-I-P-G-G-K-V-K-K-G-D-V-Y-K-G-V-I-V-R-T-K-T-G-V-V-R-P-D-G-S-T-I-K-F-D-Q-N-A-L-V-L-L-N-K-Q-D-E-P-I-G-T-R-V-F-G-P-V-T-R-E-L-R-A-K-K-Y-V-R-I-M-S-L-A-E-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-I-K-L-K-V-K-K-G-D-E-V-V-V-I-T-G-K-H-K-G-K-K-G-K-I-L-K-V-F-P-E-D-S-K-V-I-V-S-G-V-N-V-V-K-K-H-T-K-S-N-Q-M-S-E-G-G-I-I-T-K-E-L-P-I-H-I-S-N-I-A-H-I-D-P-K-T-G-N-P-T-K-V-A-F-K-F-L-E-D-G-S-K-V-R-V-A-K-K-S-G-E-I-I-G-K-E-G-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-L-R-F-K-E-L-Y-Q-Q-K-I-I-E-N-L-Q-K-K-F-S-Y-K-N-K-H-E-I-P-Q-I-K-K-I-V-I-N-M-G-V-G-E-A-T-A-D-S-K-V-I-N-N-A-V-N-D-L-T-L-I-S-G-Q-K-P-V-V-T-L-A-R-K-S-I-A-T-F-K-L-R-E-N-M-K-I-G-C-K-V-T-L-R-K-D-R-M-Y-D-F-L-E-R-L-V-I-V-A-L-P-R-V-K-E-F-R-G-F-S-Y-K-S-F-D-G-K-G-N-F-T-F-G-L-K-E-Q-I-V-F-P-E-I-N-Y-D-K-I-D-T-I-R-G-M-D-I-T-I-V-T-S-A-K-T-D-Q-E-S-K-F-L-L-S-G-F-N-L-P-F-Y-N"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-V-S-S-I-K-K-N-E-S-R-K-K-K-S-Q-S-L-H-N-K-R-L-A-L-K-S-K-I-Y-D-K-N-I-S-L-E-E-R-F-S-L-V-M-S-L-A-Q-L-P-R-N-S-S-S-T-R-I-R-N-R-C-E-L-T-G-R-P-R-G-V-T-R-K-F-G-I-S-R-N-K-L-R-E-L-I-G-R-G-L-V-P-G-V-V-K-S-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-T-D-N-V-A-D-M-L-T-R-I-R-N-A-Y-K-S-K-L-I-N-V-S-F-P-S-S-K-I-K-T-S-I-L-D-V-L-Q-K-E-G-Y-I-K-D-Y-I-T-T-Q-K-N-N-I-S-Y-T-E-V-A-L-K-Y-S-V-N-G-D-A-S-I-C-E-I-H-R-V-S-K-P-G-K-R-V-Y-S-A-I-K-D-L-K-G-Y-Y-N-N-M-G-I-Y-I-L-S-T-P-Y-G-V-M-S-D-R-E-A-H-I-K-N-V-G-G-E-V-I-C-K-V-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-L-P-I-T-I-P-E-G-V-K-I-G-L-N-D-L-E-V-K-I-S-G-P-K-G-E-L-S-K-T-F-K-G-N-I-A-I-S-L-A-E-N-K-L-L-V-K-P-L-A-A-N-K-N-A-R-A-M-W-G-T-A-R-S-I-I-S-N-M-V-T-G-V-K-E-G-F-K-L-K-L-E-I-N-G-V-G-Y-R-A-M-V-K-G-K-Y-L-N-L-M-L-A-K-S-H-N-T-K-I-E-I-P-S-D-I-K-I-E-M-P-K-Q-N-I-I-I-L-E-G-T-D-K-E-K-L-G-Q-F-A-S-I-I-I-K-Q-R-P-P-E-P-Y-K-G-K-G-I-K-F-E-N-Q-C-I-P-R-K-E-G-K-K-N"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-R-S-A-K-L-K-F-E-K-R-R-S-R-I-R-H-K-I-S-K-T-S-N-R-V-R-L-S-I-F-K-S-G-R-H-I-Y-A-Q-I-I-D-D-S-K-S-I-T-I-A-A-A-S-T-L-D-E-K-I-K-K-L-K-K-S-H-C-N-I-E-N-A-I-K-V-G-E-E-I-A-K-K-A-D-S-A-G-I-K-D-V-V-F-D-R-G-G-Y-K-Y-H-G-V-V-K-A-L-A-D-A-A-R-E-K-I-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-K-V-K-K-N-D-E-T-L-S-E-V-L-V-D-V-N-R-V-T-K-V-V-K-G-G-R-S-F-A-F-S-A-Y-V-V-V-G-D-K-A-G-R-V-G-A-G-H-G-K-A-K-E-V-N-E-A-R-G-K-A-K-Q-A-A-K-K-R-M-M-K-V-P-L-Y-Q-N-R-T-I-H-H-D-V-V-G-K-S-G-A-A-K-V-I-L-R-R-A-K-A-G-T-G-I-I-A-G-G-S-M-R-A-I-F-D-S-L-G-V-H-D-I-V-A-K-S-I-G-S-T-N-V-Y-A-M-I-S-A-T-F-D-A-L-N-K-L-A-S-P-K-S-I-A-M-R-R-D-K-K-V-N-E-I-S-V-K-S-A-E-I-Q-V-N-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-E-L-Y-N-N-I-G-A-K-K-N-K-K-R-I-A-R-G-I-G-S-G-K-G-K-T-G-G-R-G-I-K-G-Q-K-S-R-S-G-V-A-I-K-G-F-E-G-G-Q-T-P-I-I-K-R-L-P-K-R-G-F-N-C-I-S-T-K-K-Y-N-I-I-N-I-Y-N-I-E-E-A-L-A-D-G-R-L-S-A-D-D-N-I-T-K-E-K-L-V-E-A-R-V-V-N-N-K-N-N-K-K-L-V-K-L-L-S-I-C-S-D-D-F-A-A-P-L-S-L-K-L-D-A-Y-S-S-K-A-K-D-L-I-E-K-A-G-G-K-L-L"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-S-V-N-I-P-D-N-K-R-L-V-V-S-L-T-Y-I-Y-G-L-G-P-A-M-A-A-E-I-C-N-K-A-K-I-S-K-D-K-K-V-K-E-L-T-D-Q-E-L-I-G-L-R-N-I-I-E-S-E-Y-K-V-E-G-D-L-R-R-E-V-T-L-N-I-K-K-K-K-D-I-R-C-Y-Q-G-L-R-H-I-R-K-L-P-V-R-G-Q-N-T-H-S-N-A-R-T-R-K-G-K-A-I-A-I-A-G-K-K-K-A-V-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-N-Q-T-V-K-V-K-K-K-K-K-T-I-T-L-G-V-V-H-I-R-A-S-F-N-N-T-I-V-T-F-T-D-I-Q-G-N-T-I-A-S-A-S-A-G-G-N-G-F-K-G-A-R-K-A-T-P-Y-A-A-Q-V-T-I-D-R-A-S-E-K-A-K-E-Y-G-L-K-T-I-S-I-R-I-G-G-P-G-A-Q-R-E-S-A-M-R-A-L-F-G-Q-N-F-V-V-T-S-I-L-D-V-S-S-I-A-H-N-G-V-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-S-S-A-K-K-A-A-R-Q-T-V-K-R-T-L-I-N-K-K-R-S-S-A-I-K-T-F-I-K-K-V-V-H-E-I-S-I-G-N-K-E-N-A-N-I-A-L-S-V-A-Q-S-K-I-M-Q-G-V-K-K-N-I-I-K-L-N-T-A-S-R-K-I-S-R-L-S-R-Q-I-K-S-L-K-V-N-N-T-L"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-I-D-D-N-I-E-N-N-E-Q-T-I-N-D-I-A-E-E-I-V-E-T-A-N-P-E-V-T-A-L-K-A-E-I-E-E-L-K-D-K-L-I-R-T-T-A-E-I-D-N-T-R-K-R-L-E-K-A-R-D-E-A-K-D-Y-A-I-A-T-F-A-K-E-L-L-N-V-S-D-N-L-S-R-A-L-A-H-K-P-A-N-S-D-V-E-V-T-N-I-I-A-G-V-Q-M-T-K-D-E-L-D-K-V-F-H-K-H-H-I-E-E-I-K-P-E-I-G-S-M-F-D-Y-N-L-H-N-A-I-A-Q-I-E-H-P-D-H-A-P-N-S-I-I-T-L-M-Q-S-G-Y-K-I-R-D-R-L-L-R-P-A-T-V-Q-V-V-K-K-P"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-S-F-K-P-L-H-D-R-I-A-I-K-P-I-E-Q-E-E-K-T-K-G-G-I-I-I-P-D-T-V-K-E-K-P-M-Q-G-E-I-V-A-V-G-N-G-I-R-N-E-K-G-E-I-H-P-L-E-L-K-V-G-D-K-V-L-Y-G-K-W-A-G-T-E-I-E-I-K-G-T-K-L-I-V-M-K-E-S-D-V-F-G-I-I-N"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-S-I-T-S-L-K-N-Q-K-E-F-E-L-I-N-K-L-G-K-K-L-H-E-R-Y-F-I-L-V-I-A-T-K-L-P-K-I-F-L-E-S-K-Y-N-T-F-L-G-I-K-V-S-R-K-L-N-K-K-A-V-V-R-N-K-I-K-R-R-I-R-H-L-I-R-I-I-V-S-D-S-S-F-K-A-I-K-F-A-M-I-I-I-P-R-K-G-F-E-E-I-N-F-S-H-L-N-Y-E-L-S-K-V-I-L-R-N-I"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-A-K-S-G-K-I-S-K-N-R-H-K-K-I-L-K-L-A-K-G-Y-R-G-R-A-N-S-C-F-R-V-A-I-E-K-V-E-K-A-L-Q-Y-A-Y-R-D-R-R-N-R-K-R-D-F-R-G-L-W-I-Q-R-I-N-A-A-V-R-E-H-G-L-V-Y-S-Q-F-M-G-A-L-K-K-T-E-I-D-I-D-R-K-V-L-A-E-L-A-V-N-N-S-D-G-F-V-S-I-V-E-K-A-K-A-H-I"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-L-L-V-I-G-L-G-N-P-G-K-E-Y-Q-Y-T-R-H-N-V-G-F-I-A-I-E-K-I-V-N-Q-Y-N-S-S-F-S-T-K-K-K-F-N-C-E-I-A-E-T-I-S-D-G-Q-K-I-I-F-I-K-P-T-T-Y-M-N-L-S-G-K-S-V-I-S-V-K-T-Y-Y-N-I-Y-P-A-K-I-F-V-I-H-D-D-I-D-L-E-T-G-R-I-K-F-K-T-G-G-G-N-G-G-H-N-G-L-K-S-I-D-G-V-I-G-N-N-Y-N-R-I-R-I-G-V-G-R-P-Q-N-N-Q-G-V-A-D-Y-V-L-N-H-F-S-K-P-E-Y-E-T-V-M-Q-A-I-D-R-I-T-S-N-F-G-L-I-L-E-N-K-L-E-E-F-K-N-K-I-A"} +{"text": "### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate forming two phosphate ions ### SEQUENCE -M-F-I-D-K-I-K-A-K-A-N-N-Y-E-I-N-V-I-I-E-I-P-M-N-S-G-P-I-K-Y-E-F-D-K-E-S-G-A-I-F-V-D-R-F-M-Q-T-T-M-S-Y-P-C-N-Y-G-F-I-P-H-T-L-S-N-D-G-D-P-V-D-V-L-V-V-A-H-H-P-V-V-P-G-S-V-I-K-C-R-A-V-G-V-L-M-M-E-D-E-S-G-L-D-E-K-I-I-A-V-P-T-S-K-L-D-I-T-F-D-H-I-K-E-L-D-D-L-C-D-M-L-K-Q-R-I-V-H-F-F-E-H-Y-K-D-L-E-K-G-K-W-V-K-V-T-G-W-E-N-K-S-K-A-D-A-L-I-N-E-G-I-D-R-V-S"} +{"text": "### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-S-A-N-T-Q-D-N-Q-A-N-N-N-D-T-I-E-I-Q-E-T-E-V-V-P-A-E-T-N-S-L-Q-S-G-L-T-S-L-I-P-M-V-L-I-F-A-V-F-Y-F-L-L-L-R-P-Q-E-T-R-R-K-E-R-E-K-L-V-S-E-V-K-K-G-E-E-V-L-T-N-S-G-I-Y-G-I-V-T-K-V-S-E-N-D-N-N-I-E-I-E-I-A-K-D-V-R-I-K-V-L-K-S-A-I-I-D-I-T-S-R-T-K-E-V-A-V-K-K-E-N-K-K-N-K-K-V-S-G-A-K-A-S"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-A-E-D-C-N-K-I-I-P-D-R-F-R-L-V-V-L-A-T-R-Y-A-K-L-L-N-Y-K-V-E-T-N-Q-I-K-K-E-K-R-D-K-P-P-V-I-A-L-R-R-I-A-A-G-K-V-S-V-A-Q-L-E-Q-D-L-I-N-S-L-R-T-R-T-M-I-E-P-L-V-N-Q-D-E-S-E-A-V-E-E-K-F-E-Y-L-P-E-V-Y-I-G-E-D-Y-S-D-L-D-D-Q-I-F-I-D-E-N-G-E-D-Y-E-T-D-K"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-L-I-G-V-G-T-D-I-V-Q-I-P-R-I-E-K-I-L-H-L-Y-P-E-L-F-A-K-K-I-L-T-S-K-E-L-K-Q-F-A-L-L-G-K-I-N-H-A-A-F-L-A-K-R-F-A-A-K-E-A-V-S-K-A-F-G-V-G-I-G-Q-G-I-N-F-K-D-I-T-I-L-N-N-D-L-G-K-P-I-V-E-V-S-S-N-Y-T-N-T-L-S-P-F-N-I-H-L-S-L-A-D-D-Y-P-V-C-V-A-F-A-V-I-E-S-S-Y-N-V-I-L-G"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-Q-T-I-E-Q-Q-I-A-N-V-I-E-E-S-L-T-D-M-G-F-E-L-V-L-V-K-F-K-G-V-N-P-K-V-V-E-I-L-I-D-S-L-N-S-E-K-I-S-V-E-D-C-T-K-A-S-R-T-I-S-A-I-L-D-V-E-D-L-I-E-A-A-Y-S-L-E-V-A-S-S-G-L-E-R-P-L-V-K-F-E-N-Y-N-R-F-L-E-R-E-V-K-I-K-L-K-E-L-L-N-G-K-T-R-Y-Q-G-K-I-I-K-A-E-N-N-K-I-Y-L-K-C-E-E-Q-E-V-L-I-D-Y-D-L-I-K-N-A-N-L-V-L-T-E-E-V-F-K-K-L-L-K-Q"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-Y-L-F-I-N-I-I-R-R-H-F-I-S-K-N-N-F-P-K-A-N-R-E-I-R-A-R-E-V-R-L-V-G-E-N-G-E-M-H-G-V-V-N-I-R-E-A-L-D-M-A-E-R-A-G-L-D-L-V-E-I-S-P-N-A-V-P-P-V-C-K-I-L-D-F-G-K-F-K-Y-E-S-K-K-R-L-H-E-A-R-K-K-Q-K-I-V-V-L-K-E-M-K-F-K-P-N-I-S-I-G-D-F-E-T-K-L-R-K-I-K-E-F-L-K-D-G-D-K-V-K-I-S-L-W-F-K-G-R-E-I-L-H-K-E-V-G-Q-E-L-F-K-R-I-E-V-G-L-E-G-L-V-K-I-D-Q-H-A-K-M-E-G-K-Q-M-I-M-I-V-S-P-D-I-K-V-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-I-T-T-E-R-K-Q-Q-L-I-K-E-Y-A-I-T-E-N-D-T-G-S-S-A-V-Q-C-A-I-L-T-E-R-I-N-N-L-T-E-H-F-K-S-N-H-K-D-H-T-S-R-R-G-L-L-I-L-V-G-R-R-R-R-L-L-N-Y-I-K-K-N-N-V-S-K-Y-L-D-L-I-S-K-L-G-I-R-K-I-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-K-L-T-K-T-H-S-H-R-Q-Q-K-L-A-S-I-I-N-E-A-L-I-E-I-L-R-R-G-K-M-L-D-S-R-L-F-D-C-P-L-T-I-T-K-V-I-V-T-A-D-L-K-I-A-N-C-Y-F-L-P-F-N-T-K-L-T-I-D-E-I-M-D-A-L-N-N-S-K-N-A-I-R-N-F-I-T-N-K-I-N-M-K-F-S-P-D-I-R-F-H-Y-D-H-G-F-D-N-A-I-K-V-A-H-L-L-K-D-L"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-T-E-Y-K-K-V-I-A-Q-N-K-K-A-L-F-N-Y-F-I-E-E-R-L-E-A-G-I-V-L-K-G-S-E-V-R-S-L-R-Q-G-K-A-S-I-E-E-S-H-A-A-D-T-R-H-E-V-F-L-Y-N-C-H-I-A-E-Y-E-K-A-N-R-F-N-H-A-T-R-R-P-R-K-L-L-L-H-T-K-E-I-K-K-I-I-G-R-I-R-I-K-G-Y-T-L-V-A-L-S-M-Y-F-N-K-K-N-K-V-K-V-E-L-G-I-A-K-G-K-K-L-H-D-K-R-E-S-I-K-E-K-D-W-K-R-D-Q-S-R-L-I-R-Q-K"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-I-T-Q-V-K-I-K-K-L-E-N-F-S-G-S-L-P-E-Y-A-T-E-H-S-A-G-M-D-L-I-A-A-N-E-Q-P-I-T-I-K-A-A-A-I-Q-L-I-P-T-G-I-A-I-A-L-P-D-S-F-E-A-Q-I-R-P-R-S-G-L-A-V-K-H-G-I-T-V-A-N-S-P-G-T-I-D-A-D-Y-R-G-E-I-K-V-I-L-I-N-L-G-K-E-D-F-I-I-E-K-G-M-R-I-A-Q-M-I-I-A-K-Y-E-R-I-L-W-E-E-S-S-S-L-M-E-T-M-R-G-S-G-G-F-G-S-T-G-V"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-L-K-L-L-S-E-I-G-P-V-I-A-F-F-A-G-F-F-Y-G-G-G-I-Q-H-A-T-L-Y-M-L-I-T-S-V-I-C-I-T-L-C-Y-V-I-D-K-K-V-S-K-L-S-I-I-S-T-T-V-L-L-V-S-G-S-I-T-L-I-S-G-D-S-M-Y-I-K-I-K-P-T-I-L-Y-V-I-F-G-I-I-F-L-M-S-G-I-R-K-N-P-F-I-K-Y-A-L-E-S-I-V-R-L-K-E-E-S-W-I-T-L-S-Y-R-T-A-A-F-F-F-F-M-A-V-V-N-E-V-V-W-R-N-C-S-D-E-T-W-V-K-F-K-V-F-G-V-I-P-I-T-F-I-F-I-L-L-Q-L-P-L-L-L-K-N-K-L-P-D-S-K-I"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur ### SEQUENCE -M-N-T-K-I-T-N-F-T-F-D-K-K-N-L-N-L-A-E-E-I-I-K-K-Y-P-P-H-G-K-R-S-A-I-L-P-L-L-D-L-A-Q-R-Q-N-G-G-W-L-P-V-P-A-I-E-Y-V-A-N-M-L-A-M-P-Y-I-R-A-Y-E-V-A-T-F-Y-T-M-F-N-L-K-R-V-G-K-Y-H-I-Q-V-C-T-T-T-P-C-W-L-R-G-S-D-D-I-M-K-I-C-E-K-K-L-G-V-K-L-K-E-T-T-E-D-Q-K-F-T-L-S-E-I-E-C-L-G-A-C-V-N-A-P-V-V-Q-I-N-D-D-Y-Y-E-D-L-T-Q-D-K-M-G-K-I-I-D-K-L-Q-N-D"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-T-N-T-K-T-L-E-A-N-I-S-F-E-E-A-L-K-E-L-E-E-I-V-K-K-I-D-N-G-Q-E-S-L-E-T-A-V-N-S-F-E-R-G-I-L-L-K-N-H-C-E-K-K-L-K-E-A-R-L-K-I-E-K-I-T-K-L-A-D-S-T-V-V-L-E-E-M-E-V"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-N-S-L-E-N-L-I-L-V-G-V-I-K-S-C-H-G-I-K-G-H-V-M-L-K-S-F-T-D-P-A-T-K-I-L-E-R-N-L-V-N-E-S-G-A-N-I-H-I-K-L-I-S-Q-N-A-K-G-E-L-I-C-T-F-N-D-I-A-T-R-N-E-A-E-N-L-K-G-Y-K-I-F-C-L-R-A-S-L-P-E-L-E-E-D-E-F-Y-I-A-D-L-T-H-L-P-V-L-N-Q-D-H-K-E-I-G-K-I-K-N-I-L-N-F-G-A-G-D-I-I-E-I-E-F-S-N-Q-T-T-E-L-L-P-F-N-K-E-F-F-P-I-I-T-K-D-Y-V-I-L-N-Y-Q-R-E-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-I-I-K-N-L-Q-E-F-Y-R-L-L-I-P-N-V-P-L-I-A-I-D-Y-G-N-K-K-L-G-I-A-L-S-N-Q-E-R-S-I-A-M-P-L-N-T-I-T-E-I-N-K-K-I-V-I-T-S-L-L-N-I-I-E-K-Y-K-V-C-G-V-I-I-G-L-P-I-D-M-S-G-A-V-T-E-Q-T-N-I-V-M-K-F-A-E-E-L-A-K-S-I-N-L-P-I-Y-L-Q-D-E-R-L-T-T-K-A-A-N-N-L-L-K-S-F-G-V-K-R-K-D-R-N-N-N-D-D-A-V-A-A-S-M-I-L-E-T-V-L-D-S-I-K-N-I"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-N-S-E-F-S-K-I-A-E-T-T-I-A-Y-I-A-E-K-I-E-E-Q-D-K-E-A-S-I-D-V-D-L-Q-G-D-I-L-N-L-D-T-D-K-G-V-Y-V-I-N-K-Q-S-A-A-K-E-I-W-L-S-S-P-V-S-G-P-Y-H-F-F-Y-E-Q-G-E-W-T-N-R-A-G-L-E-L-M-A-I-L-T-E-E-L-N-I-K-F-D-T-R-P-T"} +{"text": "### FUNCTION Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I ### SEQUENCE -M-S-K-K-S-N-K-N-L-A-F-S-L-L-G-L-I-I-S-M-V-L-L-S-F-A-S-V-P-I-Y-N-L-F-C-K-V-T-G-Y-G-G-T-T-A-K-E-T-V-S-V-Y-S-K-V-K-G-T-K-P-I-I-I-E-F-D-A-N-V-D-K-D-L-P-W-R-F-I-P-R-Q-Q-R-V-Q-I-V-P-G-Q-N-T-L-V-F-Y-E-T-E-N-L-S-D-N-D-I-I-G-T-S-V-Y-N-V-T-P-N-K-A-G-K-Y-F-V-K-I-H-C-F-C-F-E-E-Q-L-L-K-A-G-E-R-V-L-M-P-V-T-F-Y-I-D-K-D-F-E-L-D-P-E-M-Q-D-I-K-V-L-T-L-S-Y-S-F-F-K-V-R-E-M-S-S-L-R-G-N-Y-V-S-N"} +{"text": "### FUNCTION May be involved in electron transfer from bc1 complex to aa3 ### SEQUENCE -M-S-G-K-E-L-N-K-I-V-A-A-I-L-F-A-S-L-I-A-M-M-V-G-F-V-A-N-I-L-Y-K-P-T-L-E-L-Q-H-R-G-Y-S-V-A-V-Q-E-S-S-E-N-Q-N-T-T-A-L-E-Q-A-P-V-N-I-P-E-L-M-K-T-A-N-A-D-N-G-R-E-I-A-K-K-C-L-M-C-H-S-L-D-K-D-G-P-N-K-L-G-P-H-L-W-D-V-T-G-R-P-K-A-S-I-A-D-Y-K-Y-S-P-A-L-S-K-L-G-G-V-W-D-D-D-S-L-F-A-F-L-H-K-P-S-S-Y-A-P-G-T-K-M-S-F-A-G-I-S-K-P-Q-D-I-A-D-V-I-L-F-L-K-T-Y-V-H-D-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-I-S-A-N-S-I-R-T-G-N-I-L-V-Y-N-N-D-L-W-V-V-S-K-T-P-E-H-T-Q-P-G-K-G-G-A-Y-V-Q-V-E-M-K-N-L-K-T-G-T-K-R-N-E-R-F-S-S-A-N-Y-L-E-K-A-E-L-E-Q-K-D-Y-Q-F-L-Y-F-E-G-D-D-L-V-L-M-D-T-K-H-F-D-Q-I-N-I-S-K-E-M-L-E-E-K-L-S-F-L-T-E-N-M-I-V-K-V-E-F-Y-N-D-K-P-L-N-I-E-L-P-P-T-V-I-L-E-I-S-E-T-D-P-V-I-K-G-A-T-A-T-A-S-Y-K-S-A-I-L-E-N-G-I-K-V-K-V-P-Q-Y-L-E-I-G-E-K-I-V-V-K-T-D-D-M-T-Y-V-E-R-A-K"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-S-N-S-S-K-K-H-L-D-L-P-Y-R-P-G-V-G-M-M-I-L-N-A-N-N-H-I-F-V-G-K-R-I-D-T-K-I-S-A-W-Q-M-P-Q-G-G-I-V-P-G-E-T-P-S-I-A-A-M-R-E-M-L-E-E-I-G-S-D-K-G-Y-I-I-A-E-S-K-F-W-Y-S-Y-D-V-P-S-F-L-I-P-K-L-W-N-G-N-F-R-G-Q-K-Q-R-W-F-L-I-R-F-T-G-N-N-E-D-I-N-I-N-T-S-N-P-E-F-D-Q-W-R-W-A-S-L-D-E-L-L-S-I-I-I-P-F-K-R-K-L-Y-Q-A-V-V-K-E-F-E-S-L-I-Q"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-Y-S-A-K-P-S-E-I-E-K-K-W-W-V-I-D-A-K-N-I-V-L-G-R-L-A-S-R-V-A-N-M-L-R-G-K-H-K-P-S-F-T-P-H-L-D-C-G-D-N-I-I-I-I-N-A-E-H-V-K-L-T-G-K-K-A-N-P-K-D-G-K-I-Y-Y-R-Y-T-G-F-P-G-G-I-K-D-T-T-A-G-K-I-L-S-G-K-H-P-E-R-V-I-K-M-A-V-K-R-M-I-T-R-N-A-L-G-A-K-Q-M-S-N-L-Y-V-Y-A-N-G-D-H-P-H-M-A-Q-Q-P-T-V-Y-D-F-A-S-Q-N-P-K-N-K-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-I-L-P-I-V-T-A-P-D-E-R-L-K-Q-K-S-Q-P-V-L-E-F-T-D-Q-T-R-K-F-M-D-D-M-L-K-T-M-Y-H-E-D-G-A-G-L-A-A-V-Q-V-G-V-L-K-R-I-L-V-I-D-I-Q-D-H-D-S-V-A-R-P-K-D-F-Y-P-L-F-I-V-N-P-E-I-I-E-K-A-E-E-L-V-T-A-N-E-G-C-I-S-L-P-E-Q-R-I-E-V-A-R-P-E-S-I-K-I-R-Y-L-D-Y-H-G-K-S-R-E-L-K-A-N-D-W-L-A-R-V-I-Q-H-E-Y-D-H-L-E-G-K-L-M-I-D-Y-L-S-N-L-K-R-D-V-V-L-R-K-L-K-K-L-K-N-N-I-V"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-N-K-A-I-L-H-T-I-I-V-Y-T-L-A-S-C-P-Y-C-I-K-A-K-A-L-L-D-E-K-N-V-A-Y-E-E-I-E-V-S-N-F-T-Q-E-E-K-E-K-F-I-K-K-S-G-G-K-K-T-V-P-Q-I-F-I-D-N-M-H-V-G-G-C-D-A-L-F-D-L-E-K-E-G-R-L-D-K-L-L-E-N-Q-P-K-T-T-S-P-A-A-G-A"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-Q-N-Y-F-Q-L-L-G-L-P-Q-E-Y-N-I-N-L-K-I-L-E-K-Q-Y-F-A-M-Q-V-K-Y-H-P-D-K-A-K-T-L-Q-E-K-E-Q-N-L-I-T-A-A-E-L-N-N-A-Y-S-T-L-K-D-A-L-K-R-A-E-Y-M-L-L-L-Q-N-I-N-L-N-D-E-K-T-R-S-L-L-S-P-L-E-L-S-I-F-W-D-E-M-E-I-I-E-N-T-I-L-F-S-D-L-E-K-I-K-D-K-Y-E-L-M-K-K-L-E-I-D-S-L-K-Q-A-F-E-E-Q-N-L-S-D-A-T-I-K-T-S-K-L-K-Y-I-G-T-L-L-H-K-L-Q-E-K-I-K-S-C-K"} +{"text": "### FUNCTION Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-S-G-K-I-K-V-T-F-I-I-N-D-G-E-E-K-T-V-E-A-P-I-G-L-S-I-L-E-I-A-H-S-N-D-L-D-L-E-G-A-C-E-G-S-L-A-C-A-T-C-H-V-I-L-E-E-E-F-Y-N-K-L-K-K-P-T-E-A-E-E-D-M-L-D-L-A-F-G-L-T-D-T-S-R-L-G-C-Q-I-I-L-T-E-E-L-D-G-I-K-V-R-I-P-A-T-T-R-N-I-K-L"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-E-F-I-A-F-M-T-D-H-G-H-N-H-K-H-A-S-H-K-T-L-T-K-A-E-A-E-K-A-L-N-L-V-L-D-S-V-I-S-A-I-K-S-H-H-N-I-N-I-T-G-F-G-S-F-E-I-H-H-R-K-A-R-E-G-R-N-P-K-T-G-A-K-M-K-I-D-A-Y-N-Q-P-T-F-R-A-G-R-K-M-K-E-A-C-N"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-S-N-K-I-N-K-K-S-I-A-R-I-A-A-V-Q-A-I-Y-Q-N-I-L-Q-N-N-D-D-M-D-D-I-M-Q-N-V-L-S-F-Y-Q-N-N-N-A-I-T-D-L-P-E-N-L-K-I-S-L-S-I-S-H-F-K-M-L-V-K-S-V-F-E-N-I-H-K-L-D-E-I-I-D-N-H-L-T-N-D-K-D-P-A-H-M-P-I-L-L-R-A-L-L-R-V-S-I-C-E-L-L-F-C-P-T-T-P-A-K-V-V-I-N-E-Y-T-D-I-A-N-D-M-L-N-E-H-E-I-G-F-V-N-S-V-L-D-K-I-A-K-E-H-T-R-L-I"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-D-K-E-H-L-K-K-N-L-Q-E-K-M-E-K-A-L-K-V-L-D-H-E-L-K-G-L-R-T-G-R-A-S-V-N-L-L-D-S-V-T-V-E-A-Y-G-S-K-M-P-L-S-Q-V-A-S-L-S-T-P-D-A-R-T-I-N-V-Q-V-W-D-K-S-M-V-S-S-V-E-K-G-I-T-I-A-N-L-G-L-T-P-A-T-D-G-Q-L-I-R-L-P-I-P-A-L-T-E-E-R-R-T-A-L-V-K-L-A-H-K-Y-G-E-D-T-K-I-S-L-R-N-I-R-R-D-G-N-E-A-L-K-K-L-E-K-D-N-V-I-A-K-D-E-H-H-S-L-S-E-Q-V-Q-K-L-T-D-D-Y-S-S-K-V-D-S-V-I-K-Q-K-E-Q-E-I-M-T-V"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-D-L-A-K-I-E-E-Q-L-S-S-L-T-L-M-Q-A-A-E-L-V-K-M-L-E-E-K-W-G-V-S-A-A-A-P-V-A-V-A-A-V-G-A-A-A-P-A-A-E-A-V-A-E-K-T-E-F-E-V-V-L-T-A-A-G-D-K-K-V-E-V-I-K-V-V-K-D-I-T-G-L-G-L-I-E-A-K-K-L-V-D-E-A-P-K-P-I-K-S-N-V-K-K-A-E-A-D-E-I-K-G-K-L-E-A-A-G-A-K-V-E-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-L-R-S-E-K-P-V-A-V-E-D-I-V-N-I-Y-K-E-S-P-S-I-I-I-T-H-Y-H-G-L-T-V-S-Q-V-S-S-L-R-E-S-L-K-S-K-E-A-G-F-K-V-V-K-N-T-L-A-K-I-A-A-N-Q-T-G-L-N-S-I-V-N-L-F-A-G-P-T-A-I-V-Y-S-K-E-P-V-E-M-A-K-L-V-V-N-F-A-K-A-N-D-N-L-K-I-I-G-G-I-V-D-N-H-V-L-D-E-H-S-I-K-E-L-S-K-L-P-T-L-N-E-L-R-G-K-I-V-G-L-L-Q-A-P-A-T-K-V-V-G-V-L-Q-A-P-S-S-S-M-A-R-V-I-Q-A-H-A-S-K-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-S-Q-K-A-I-K-G-Y-I-N-L-I-I-P-A-A-G-A-T-P-A-P-P-I-G-P-A-L-G-Q-R-K-V-N-I-A-A-F-C-K-D-F-N-D-A-T-Q-G-M-E-K-G-I-P-L-P-T-V-I-T-V-Y-E-D-S-S-F-S-F-K-I-K-T-P-P-A-S-Y-F-L-K-K-Y-A-K-I-T-K-G-S-S-A-T-K-K-E-A-V-V-G-K-V-T-M-D-D-C-R-E-I-A-K-L-K-M-P-D-L-N-T-K-N-I-E-A-A-T-K-I-I-C-G-S-A-A-S-M-G-L-E-V-V-G-N"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-T-A-Q-S-I-D-N-I-L-S-S-S-E-K-N-V-K-Q-W-Y-V-V-H-T-A-S-G-A-E-K-R-I-K-E-D-M-L-R-K-I-A-K-Q-N-M-T-H-F-F-E-D-I-L-I-P-V-F-G-V-S-E-V-K-R-G-K-N-V-K-V-E-K-K-L-M-P-S-Y-I-L-I-K-M-N-M-T-D-K-S-W-H-L-V-K-N-I-S-G-V-T-G-F-L-G-S-K-T-T-P-K-A-L-T-E-S-E-I-Q-N-I-F-N-N-L-E-A-E-A-K-E-A-K-N-S-K-L-Y-E-V-G-E-I-V-T-V-T-D-G-P-F-E-T-F-M-G-T-V-E-E-I-D-Q-E-K-N-R-L-K-V-S-V-A-I-F-G-K-A-T-P-I-E-L-N-F-N-Q-V-K-K-N-D"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-F-K-E-Y-K-I-Y-K-F-F-E-Q-V-K-Q-E-T-Y-K-V-V-W-P-T-R-K-E-L-V-A-S-T-L-V-V-V-V-A-V-F-I-F-S-L-I-C-L-V-L-D-Y-S-I-H-N-I-M-Q-L-L-L-N-I-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-A-A-E-K-R-V-I-L-P-D-M-K-Y-N-S-I-L-L-S-R-F-I-N-N-I-M-K-E-G-K-K-A-L-A-E-K-I-V-Y-S-A-F-N-K-I-E-K-K-H-R-V-D-P-Y-Q-T-F-N-N-A-M-H-N-V-K-P-H-L-E-V-T-S-V-R-V-G-G-A-N-Y-Q-V-P-T-H-V-D-E-R-R-G-Y-A-L-A-S-R-W-I-I-N-A-A-S-K-R-S-E-K-M-M-I-D-K-L-A-E-E-L-F-E-A-S-N-N-R-G-V-A-I-K-K-K-E-D-T-H-K-M-A-E-A-N-K-A-F-S-H-F-S-P-K-K-M-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-Y-N-Q-L-V-R-F-G-R-K-S-K-T-R-K-T-K-S-P-A-L-E-S-N-P-F-K-S-G-V-C-L-V-V-K-T-V-T-P-K-K-P-N-S-A-L-R-K-I-A-T-V-R-L-S-N-K-R-T-V-N-A-Y-I-P-G-E-K-H-S-V-K-E-H-D-R-V-L-V-R-G-G-Q-V-P-D-L-P-G-V-K-Y-H-I-V-L-G-A-Y-D-I-A-G-V-K-G-R-K-Q-G-R-S-R-Y-G-A-P-R-K-Q-V-A-V-T-K-K"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-I-I-D-R-F-E-Q-E-N-I-S-K-R-T-A-N-K-K-I-P-D-F-E-A-G-D-T-V-K-V-T-V-K-I-I-D-R-S-I-E-K-D-G-K-E-K-L-T-E-R-F-Q-A-Y-E-G-V-V-I-A-K-R-N-R-G-I-T-S-S-F-L-V-R-K-I-S-H-G-E-G-V-E-R-R-F-M-T-Y-S-P-M-V-H-S-I-D-V-V-K-Y-G-V-V-R-R-A-K-L-Y-Y-L-R-N-R-S-G-K-S-A-R-I-K-E-R-H-I-P-I-A-K-T-K-A-A-K-A"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-S-S-I-H-P-E-Y-K-K-F-L-I-K-V-G-S-D-V-F-E-T-M-S-T-H-P-T-G-E-I-L-M-D-V-D-F-R-K-H-P-A-W-N-K-D-S-G-N-V-V-N-Q-S-N-K-S-V-S-D-F-N-K-R-F-S-G-L-S-F-G-S-K-K-E-A-S"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-I-D-I-L-L-F-V-H-I-T-I-A-I-L-L-I-I-V-I-L-M-Q-R-S-G-S-D-G-I-S-S-I-S-G-G-N-N-M-G-V-V-S-A-K-T-V-G-N-F-L-T-K-S-T-I-I-L-T-T-L-F-L-I-N-A-I-V-L-A-N-L-S-S-K-K-K-S-D-L-V-S-K-I-N-E-I-E-E-N-Q-A-E-N-S-L-P-I-A-K"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-T-I-N-T-D-T-N-E-T-M-P-H-I-S-V-N-A-Q-Y-I-K-D-L-S-L-E-N-P-S-A-P-S-S-L-A-A-L-D-Q-R-P-Q-I-D-L-S-L-D-I-N-I-T-N-L-S-E-E-N-F-Y-E-V-E-L-N-I-E-A-I-A-R-N-E-K-Y-K-L-F-Q-I-E-L-K-Y-A-G-V-F-N-L-I-N-I-D-S-E-Q-H-P-V-L-L-S-V-H-C-P-A-M-I-F-P-F-A-R-K-I-I-A-S-C-T-Q-D-A-G-F-Q-P-L-M-I-D-P-I-D-F-G-A-L-Y-H-K-K-M-S-E-H-Q-N"} +{"text": "### FUNCTION Specifically methylates the N7 position of guanine in position 527 of 16S rRNA ### SEQUENCE -M-M-E-V-P-R-E-I-I-E-K-L-E-I-F-Q-K-L-V-K-K-W-N-K-S-I-N-L-V-S-D-N-T-I-H-N-F-W-Q-R-H-I-L-D-S-L-Q-L-I-Q-Y-I-D-N-K-E-I-H-L-V-D-I-G-S-G-S-G-L-P-G-I-V-L-S-I-A-G-V-A-Q-V-S-L-I-E-A-D-L-R-K-C-I-F-L-E-K-A-S-K-I-S-N-N-N-I-Q-I-I-N-Q-R-I-E-K-V-E-I-D-C-S-I-L-T-C-R-A-F-S-N-L-N-T-I-F-N-C-I-K-N-I-S-V-R-E-K-F-L-L-L-K-G-K-N-Y-L-T-E-I-V-E-A-K-E-R-W-L-F-G-Y-L-I-H-Q-S-I-T-C-E-E-G-K-I-L-E-V-S-N-L-T-K-M-I"} +{"text": "### FUNCTION This protein catalyzes the committed step to the synthesis of the acidic phospholipids ### SEQUENCE -M-R-I-D-K-N-L-P-N-Y-L-T-I-A-R-I-M-V-I-P-V-I-I-L-V-F-Y-I-N-N-S-L-A-R-T-L-G-A-L-L-F-V-L-A-S-I-T-D-F-F-D-G-Y-I-A-R-K-Y-N-L-V-T-S-F-G-K-M-F-D-P-I-A-D-K-L-L-V-G-C-V-I-I-M-L-L-K-K-D-N-V-D-E-I-P-C-L-L-I-L-A-R-E-F-L-V-S-G-L-R-E-F-L-A-L-V-K-V-S-V-P-V-S-R-L-A-K-V-K-T-F-L-Q-M-F-A-L-S-I-L-I-L-G-S-K-G-S-G-I-I-Y-L-D-I-V-G-E-I-I-L-W-I-A-A-F-L-T-I-I-T-G-Y-S-Y-F-K-A-C-K-K-Y-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-I-I-L-I-K-P-V-R-K-L-G-K-I-G-D-I-L-K-V-A-D-G-F-G-R-N-Y-L-L-P-Q-K-L-A-I-R-A-T-E-P-N-K-E-L-I-V-K-Q-K-H-E-F-E-A-K-D-K-Q-I-R-E-E-V-E-K-I-N-A-L-I-K-D-Q-Q-L-V-F-I-R-Q-T-S-N-D-G-K-L-F-G-S-V-T-N-K-E-I-A-D-K-L-S-E-N-I-S-Y-N-I-S-H-S-N-I-I-L-D-K-Q-I-K-S-T-G-I-Y-T-V-E-I-R-L-H-A-E-L-N-A-I-V-T-V-I-V-A-R-S-E-S-E-A-Q-D-Y-L-R-E-Q-K-T-E-T-S-E-D-L-A-E-L-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-L-K-S-N-N-A-S-E-T-A-A-H-K-V-G-D-K-T-A-K-K-V-F-F-R-R-R-K-G-C-P-L-S-V-P-N-A-P-V-I-D-Y-K-N-P-E-L-L-I-K-F-V-S-E-G-G-R-M-L-P-S-R-I-T-N-V-C-A-K-K-Q-R-K-L-N-N-A-I-K-I-A-R-I-L-A-L-L-P-F-V-F-Q-A-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-F-Y-E-S-V-F-I-I-R-Q-D-V-S-L-N-D-I-D-K-I-V-D-D-F-A-K-I-I-K-D-N-N-G-T-I-I-K-K-E-Y-W-G-L-R-T-L-A-Y-K-I-G-N-N-K-K-G-H-Y-Y-F-L-G-L-D-I-T-G-N-V-K-E-E-L-E-R-K-M-K-L-N-E-N-I-I-R-F-L-T-I-Q-A-D-S-I-S-S-E-P-S-P-I-L-K-N-Q-S-T-E-N-T-P-V-I-D-V-T-I-N-N"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-F-L-D-E-S-F-W-L-A-V-S-F-V-I-F-L-Y-L-V-Y-R-P-A-K-K-A-I-L-N-S-L-D-A-K-I-L-E-V-Q-E-K-V-L-Q-A-E-K-L-K-E-D-A-A-L-L-F-K-H-T-N-A-Q-I-K-K-L-E-T-L-R-S-Q-M-I-E-D-S-N-E-V-T-K-K-I-I-Q-E-K-T-K-E-I-E-E-F-L-E-H-K-K-S-D-A-I-Q-L-M-Q-N-Q-K-S-T-A-S-K-E-L-Q-D-E-F-C-D-E-V-I-K-L-V-S-E-Y-F-Q-S-V-K-L-S-E-S-N-I-A-K-N-L-M-D-K-S-D-F-P-Q-D-E-G-K-A-T"} +{"text": "### FUNCTION Required for the formation of a threonylcarbamoyl group on adenosine at position 37 ### SEQUENCE -M-H-T-L-N-S-E-E-E-T-K-K-L-A-K-L-L-A-Q-S-L-K-P-N-D-I-V-L-L-N-G-D-L-G-A-G-K-T-F-F-C-R-E-I-I-K-Y-F-C-G-E-N-T-S-I-I-S-P-T-F-N-L-L-Q-T-Y-K-A-S-N-F-T-I-Y-H-Y-D-L-Y-R-L-K-S-P-E-E-I-Y-E-L-G-F-E-E-A-L-N-G-N-L-I-L-I-E-W-S-E-I-I-K-H-L-L-T-P-P-L-I-E-V-N-L-E-A-L-D-N-N-K-R-L-C-S-I-I-T-N-H-K-E-N-S-Q-E-S-S-L-I-D-F-L-Q-D-S-P-L-F-D-T-K-L-D-I-Q-R-D-K-S-P-T-R-K-V-K-L"} +{"text": "### FUNCTION Component of the thioredoxin-thioredoxin reductase system Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-A-N-N-V-M-D-S-S-F-K-K-E-V-L-E-S-D-L-P-V-L-V-D-F-W-A-E-W-C-G-P-C-K-M-L-T-P-I-I-D-E-I-S-K-E-L-Q-G-K-V-K-V-L-K-M-N-I-D-E-N-P-N-T-P-S-E-Y-G-I-R-S-I-P-T-I-M-L-F-K-N-G-E-Q-K-D-T-K-I-G-L-Q-Q-K-N-S-L-L-D-W-I-N-K-S-I"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-I-I-Q-Q-L-E-A-E-Q-A-A-K-I-A-A-K-R-T-L-P-E-F-S-P-G-D-T-V-R-V-N-V-R-V-V-E-G-N-R-T-R-V-Q-A-Y-E-G-V-C-I-A-R-S-G-G-G-I-N-E-S-F-T-V-R-K-I-S-Y-G-E-G-V-E-R-V-F-P-V-Y-S-P-L-V-E-S-V-D-V-V-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-D-R-R-G-K-S-A-R-I-V-E-N-T-G-T-R-A-R-K-L-N-D-A-E-R-Q-A-V-V-E-E-K-A-R-I-E-A-E-K-V-A-A-A-Q-A-L-A-A-E-K-A-A-A-E-A-A-E-A-K-A-A-E-E-A-K-A-A-E-A-A-A-E"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-Q-L-K-N-P-V-L-M-A-T-I-G-A-A-Q-G-L-R-G-E-V-R-V-K-S-F-T-D-D-P-A-A-L-G-D-Y-G-N-L-H-S-E-D-G-R-V-F-E-V-L-E-I-R-E-A-K-N-V-V-V-V-R-F-R-G-I-N-D-R-T-A-A-E-A-L-N-G-L-E-L-F-I-E-R-D-N-L-P-D-D-D-L-D-E-D-E-F-F-Y-A-D-L-E-G-L-E-A-V-D-R-T-G-K-S-Y-G-S-V-T-G-V-F-D-F-G-A-G-D-L-L-E-L-K-G-P-G-L-R-P-V-L-I-P-F-T-E-W-S-V-L-E-I-D-L-E-A-G-K-L-V-I-D-P-T-A-A-G-L-V-D-D-E-K-S-G-P-G-K-P-F-P-T-K-R-K"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-T-A-E-D-L-P-Y-R-P-C-V-G-V-M-V-L-N-R-Q-G-L-V-W-A-G-H-R-L-A-V-G-N-S-E-Y-D-G-S-P-Q-L-W-Q-M-P-Q-G-G-I-D-E-G-E-D-P-L-E-A-A-C-R-E-L-Y-E-E-T-G-I-R-S-V-S-L-L-A-E-A-P-D-W-I-H-Y-D-L-P-S-H-L-I-G-I-G-L-K-G-K-Y-R-G-Q-R-Q-R-W-Y-A-F-R-F-E-G-D-E-S-E-I-A-I-N-P-P-P-G-G-H-E-P-E-F-D-A-W-E-W-K-P-M-H-E-L-P-G-S-I-V-P-F-K-R-R-A-Y-E-E-V-V-A-A-F-S-H-L-V-R"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-A-V-G-L-F-G-G-S-F-N-P-P-H-D-G-H-A-L-V-A-E-T-A-L-R-R-L-G-L-D-Q-L-W-W-M-V-T-P-G-N-P-L-K-D-R-N-H-L-A-P-L-G-E-R-I-A-M-S-E-K-I-A-R-N-P-R-I-K-V-T-A-F-E-Q-A-L-G-Q-S-Y-T-A-R-T-L-E-V-I-R-A-R-N-R-D-V-R-F-V-W-V-M-G-A-D-N-L-K-N-F-H-R-W-Q-D-W-R-K-I-V-A-T-F-P-I-A-V-V-D-R-P-G-S-T-L-A-Y-L-S-S-P-M-A-R-A-F-S-S-A-R-V-D-E-D-D-A-G-T-L-A-F-R-R-A-P-A-W-T-F-I-H-G-P-R-S-G-L-S-S-T-A-L-R-S-A-K-S-G"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-I-K-T-G-G-K-Q-Y-R-V-A-A-N-D-V-I-T-I-E-K-L-E-G-V-A-G-D-K-I-E-F-T-E-I-L-M-V-G-V-G-A-D-A-T-I-G-A-P-F-V-E-G-A-V-V-S-A-E-V-V-D-Q-G-R-A-K-K-V-I-A-F-K-K-R-R-R-Q-N-S-K-R-S-R-G-H-R-Q-H-Q-T-I-V-R-I-L-D-I-A-A-A-G-G-K-A-K-K-A-S-K-K-T-E-A-A-A-E-A-A-N"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-L-R-L-L-F-G-F-L-V-T-C-F-L-L-L-P-A-R-A-A-E-P-Q-Y-A-I-F-A-G-G-C-F-W-C-V-E-S-D-F-D-A-V-P-G-V-L-E-T-I-S-G-Y-A-G-G-K-S-A-N-P-T-Y-E-D-Y-A-K-G-G-H-R-E-V-V-R-V-K-F-D-P-D-R-V-S-Y-A-E-L-V-G-V-L-F-R-T-T-D-P-T-D-G-D-G-Q-F-C-D-R-G-F-A-Y-T-T-A-I-H-A-L-N-E-R-Q-A-M-D-A-K-A-E-K-I-K-A-E-A-E-L-G-R-P-I-V-T-P-V-E-G-A-A-K-F-W-P-A-E-D-Y-H-Q-D-F-G-K-R-N-P-I-R-Y-W-Y-Y-R-N-G-C-G-R-N-R-T-V-E-K-L-W-G-D-R-A-Y-A-G-V-S-H"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-P-V-A-D-T-S-Q-L-I-S-G-V-A-E-R-Y-A-S-S-L-F-E-L-A-L-D-A-G-S-I-E-A-V-G-A-D-L-T-R-I-Q-A-L-I-D-G-S-D-D-L-K-R-L-I-V-S-P-V-F-S-A-D-D-Q-F-K-A-I-S-A-L-V-E-K-F-G-F-S-G-L-V-G-N-F-L-K-V-V-A-R-N-R-R-L-F-V-L-P-G-I-I-K-A-F-R-L-L-A-A-R-H-K-G-E-I-T-A-D-V-T-S-A-H-A-L-T-L-A-Q-E-I-E-L-K-A-A-L-K-G-V-T-G-K-D-V-A-V-N-V-T-V-D-P-S-I-L-G-G-L-I-V-K-V-G-S-R-Q-I-D-T-S-L-R-T-K-L-S-T-L-K-L-A-L-K-E-V-G"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-P-Y-R-S-T-E-V-L-S-P-G-P-G-E-R-A-P-L-H-R-L-T-L-T-H-E-Q-R-H-L-R-R-K-L-L-H-L-E-N-D-D-V-V-M-L-D-L-K-E-P-V-M-L-A-D-G-D-L-L-V-L-E-G-G-G-H-I-E-V-K-A-A-A-E-A-L-Y-D-I-R-A-R-N-P-L-H-L-M-E-L-A-W-H-L-G-N-R-H-L-P-A-A-V-E-E-G-R-I-L-I-A-R-D-P-V-I-R-A-M-L-E-G-L-G-A-T-V-D-E-V-N-E-P-F-H-P-L-H-G-A-Y-H-Q-H-G-H-G-D-H-Y-R-H-G"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-A-V-Q-S-E-L-I-S-A-I-R-S-I-P-D-Y-P-K-P-G-V-M-F-R-D-I-T-T-L-L-G-N-P-R-A-F-R-R-A-I-D-E-L-V-H-P-Y-A-G-T-K-V-D-K-V-A-G-I-E-A-R-G-F-I-L-G-G-A-I-A-H-Q-L-S-A-G-F-I-P-I-R-K-K-G-K-L-P-H-D-T-V-R-I-A-Y-S-L-E-Y-G-V-D-E-M-E-M-H-R-D-A-V-A-P-G-D-K-V-I-L-V-D-D-L-I-A-T-G-G-T-A-E-G-A-A-K-L-L-K-Q-M-G-A-D-I-V-A-A-C-F-I-I-D-L-P-E-L-G-G-R-K-K-L-E-A-L-G-V-N-V-R-T-L-I-E-F-E-G-H"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-D-N-D-V-A-A-K-R-L-T-K-P-K-L-E-R-P-K-L-Y-K-V-L-L-V-N-D-D-F-T-P-R-E-F-V-V-M-V-L-K-A-V-F-R-M-S-E-E-A-G-Y-R-V-M-M-T-A-H-K-M-G-I-S-V-V-V-V-C-A-K-D-V-A-E-T-K-A-K-E-A-T-D-L-G-K-E-A-G-F-P-L-L-F-T-A-E-P-E-E"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis Is involved in the transfer of long hydroxylated fatty acids to lipid A ### SEQUENCE -M-R-V-T-A-T-F-D-K-V-A-D-I-I-A-E-T-S-E-I-D-R-E-T-I-K-P-E-S-H-T-I-D-D-L-G-I-D-S-L-D-F-L-D-I-V-F-A-I-D-K-E-F-G-I-K-I-P-L-E-Q-W-T-Q-E-V-N-E-G-K-V-S-T-E-E-Y-F-V-L-K-N-L-C-A-K-I-D-E-L-R-A-A-K-A-G"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-L-K-F-T-E-E-H-E-W-L-K-I-D-G-D-V-A-T-V-G-I-T-E-H-A-A-G-Q-L-G-D-L-V-F-V-E-L-P-E-A-G-A-S-F-S-K-G-D-S-A-A-T-V-E-S-V-K-A-A-S-D-V-Y-C-P-L-D-G-E-I-V-E-V-N-Q-A-I-V-D-D-P-S-L-V-N-S-D-P-Q-G-A-A-W-F-F-K-L-K-L-A-D-P-D-A-A-N-A-L-L-D-E-A-A-Y-K-E-F-V-A"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-I-W-H-W-L-I-V-L-A-V-V-L-L-L-F-G-R-G-K-I-P-E-L-M-G-D-V-A-K-G-I-K-N-F-K-K-G-M-G-D-D-E-V-A-S-A-D-K-S-V-D-G-K-T-V-D-H-K-S-D-E-V-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-E-G-V-D-L-K-E-L-K-R-R-M-D-G-A-I-A-A-F-K-H-D-I-A-S-L-R-T-G-R-A-S-A-N-V-L-D-P-V-T-V-E-A-Y-G-S-R-M-P-L-N-Q-V-A-N-I-T-V-P-E-S-R-M-L-S-V-S-V-W-D-K-S-M-V-G-A-V-E-R-A-I-R-E-S-N-L-G-L-N-P-I-V-D-G-Q-N-L-R-I-P-L-P-E-L-N-E-E-R-R-K-S-L-V-K-V-A-H-D-Y-A-E-K-S-K-V-A-V-R-H-V-R-R-D-G-M-D-D-L-K-K-A-E-K-D-G-E-I-G-Q-D-E-S-R-A-Q-S-E-R-V-Q-K-M-T-D-D-V-I-S-E-I-D-R-L-L-A-E-K-E-K-E-I-M-Q-V"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-I-A-M-P-V-R-M-Q-Q-G-S-E-G-D-G-G-G-P-S-R-G-T-S-V-I-T-R-T-K-P-K-T-K-K-P-S-L-Y-R-V-L-L-L-N-D-D-Y-T-P-M-E-F-V-I-H-I-L-E-R-F-F-Q-K-N-R-E-E-A-T-V-I-M-L-H-V-H-N-H-G-V-G-E-C-G-V-F-T-Y-E-V-A-E-T-K-V-T-Q-V-M-D-F-A-R-Q-H-Q-H-P-L-Q-C-V-M-E-K-K"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-E-R-S-Q-N-L-Q-D-L-F-L-N-T-V-R-K-Q-K-I-S-L-T-I-F-L-I-N-G-V-K-L-T-G-V-V-T-S-F-D-N-F-C-V-L-L-R-R-D-G-H-S-Q-L-V-Y-K-H-A-I-S-T-I-M-P-G-Q-P-L-Q-M-F-E-N-E-E-A-A-S"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-H-I-L-L-V-G-A-G-G-A-L-G-S-V-L-R-Y-L-V-G-L-W-M-L-Q-R-A-G-P-A-F-P-W-G-T-L-F-V-N-V-T-G-S-F-L-I-G-F-L-A-E-F-I-M-H-K-M-G-A-S-P-E-M-R-V-F-L-I-T-G-V-L-G-G-Y-T-T-F-S-A-F-S-L-D-A-I-A-L-L-E-H-G-Q-T-M-S-G-L-A-Y-I-V-A-S-V-G-L-S-M-L-A-V-F-A-G-L-A-L-M-R-A-M-V"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-E-I-K-D-N-E-G-A-T-K-N-R-K-R-L-G-R-G-I-G-S-G-S-G-K-T-A-G-R-G-V-K-G-Q-K-A-R-S-G-V-A-I-N-G-F-E-G-G-Q-M-P-I-Y-R-R-L-P-K-R-G-F-N-N-I-F-A-S-E-F-V-V-V-S-L-G-R-I-Q-A-A-V-D-A-K-K-L-D-A-S-K-T-V-D-A-A-A-L-K-A-A-G-V-I-R-R-V-K-D-G-V-R-V-L-A-D-G-E-L-K-A-K-V-S-L-E-V-A-G-A-S-K-P-A-I-E-K-I-E-K-A-G-G-S-I-N-L-L-S-A-A-A-E"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-Q-E-R-R-G-S-R-E-D-R-Q-N-R-E-E-R-D-S-E-F-V-D-K-L-V-A-I-N-R-V-A-K-V-V-K-G-G-R-R-F-G-F-A-A-L-V-V-V-G-D-Q-K-G-R-V-G-F-G-H-G-K-A-R-E-V-P-E-A-I-R-K-A-T-E-A-A-K-R-D-L-I-F-V-P-L-R-G-G-R-T-L-H-H-D-V-H-G-R-H-G-A-G-K-V-L-L-R-S-A-K-P-G-T-G-I-I-A-G-G-P-M-R-A-V-F-E-T-L-G-V-H-D-V-V-A-K-S-T-G-S-S-N-P-Y-N-M-V-R-A-T-F-D-A-L-K-N-Q-M-H-P-K-D-I-A-A-Q-R-G-M-K-Y-A-T-L-Q-S-R-R-V-S-A-G-V-A-S-E-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-S-R-K-D-T-L-V-R-R-A-S-R-V-R-R-Q-I-K-A-V-A-N-G-R-P-R-L-S-V-H-R-S-S-K-N-I-Y-A-Q-I-I-D-D-V-A-G-K-T-I-A-S-A-S-T-L-D-T-D-L-R-S-S-L-K-T-G-A-D-T-E-A-A-T-A-V-G-K-L-L-A-E-R-A-S-K-A-G-I-K-D-V-V-F-D-R-G-A-F-I-Y-H-G-R-I-K-A-L-A-E-A-A-R-E-G-G-L-N-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-P-V-Q-V-P-A-G-V-T-A-N-V-D-G-Q-K-V-T-A-K-G-P-K-G-E-L-F-F-V-A-N-D-E-V-S-V-K-L-E-N-N-T-V-V-V-Q-P-L-N-E-S-K-D-A-R-A-K-W-G-M-S-R-T-M-I-E-N-I-L-K-G-V-K-D-G-Y-E-R-K-L-E-I-N-G-V-G-Y-R-A-S-M-Q-G-K-N-L-Q-L-A-L-G-F-S-H-D-V-V-Y-Q-T-P-E-G-I-T-I-A-V-P-K-P-T-E-I-V-V-S-G-I-N-K-Q-Q-V-G-Q-V-A-A-E-I-R-E-Y-R-G-P-E-P-Y-K-G-K-G-V-K-Y-A-E-E-R-I-V-R-K-E-G-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-A-M-T-D-P-L-G-D-M-L-T-R-I-R-N-G-A-A-R-R-K-S-S-V-S-T-P-A-S-K-L-R-A-R-V-L-D-V-L-Q-A-E-G-Y-I-R-G-Y-S-E-V-E-F-G-N-G-K-A-E-L-N-I-E-L-K-Y-Y-E-G-A-S-V-I-R-E-I-A-R-V-S-K-P-G-R-R-V-Y-V-S-V-K-S-I-P-Q-V-A-N-G-L-G-I-T-I-L-S-T-P-K-G-V-M-A-D-H-Q-A-R-E-Q-N-V-G-G-E-V-L-C-S-I-F"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-S-A-V-E-K-N-K-R-R-R-K-L-V-A-N-H-A-A-K-R-A-V-L-K-A-I-I-M-N-Q-S-L-P-I-E-E-R-F-K-A-T-L-K-L-A-E-L-P-R-D-G-S-K-T-R-I-R-N-R-C-E-V-T-G-R-P-R-A-Y-Y-R-K-L-R-M-S-R-I-A-L-R-E-L-G-N-L-G-K-V-P-G-V-V-K-S-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-S-A-Y-E-S-R-L-K-K-E-Y-V-E-R-I-R-K-A-M-Q-E-Q-F-S-Y-A-N-E-M-Q-I-P-R-L-D-K-I-V-I-N-M-G-V-G-E-A-T-G-D-S-K-K-P-T-V-A-A-A-D-L-A-A-I-A-G-Q-K-P-V-I-T-R-A-R-N-S-I-A-G-F-K-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-V-R-M-Y-D-F-L-D-R-L-I-N-I-A-L-P-R-V-R-D-F-R-G-L-N-P-K-S-F-D-G-R-G-N-F-A-M-G-I-K-E-H-I-V-F-P-E-I-N-Y-D-K-V-D-Q-M-W-G-M-D-I-I-V-C-T-T-A-T-N-D-D-E-A-R-A-L-L-K-E-F-N-F-P-F-R-Q"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-K-I-R-K-G-D-K-V-V-V-L-T-G-K-D-K-G-R-T-G-E-V-I-Q-V-M-P-K-E-D-R-A-L-V-R-G-V-N-V-V-K-R-H-Q-R-Q-T-Q-N-Q-E-A-G-I-I-T-K-E-A-S-I-H-L-S-N-I-A-I-A-D-P-K-D-G-K-P-T-R-V-G-F-K-I-D-G-D-K-K-V-R-V-A-K-R-S-G-D-V-I-D-G"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-N-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-K-Y-A-S-I-G-D-I-I-V-V-S-I-K-E-A-I-P-R-G-R-V-K-K-G-D-V-M-K-A-V-V-V-R-T-A-K-D-I-R-R-A-D-G-S-V-I-R-F-D-T-N-A-A-V-L-I-D-N-K-K-E-P-I-G-T-R-I-F-G-P-V-P-R-E-L-R-A-K-N-H-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-I-L-Q-G-T-V-V-S-D-K-N-D-K-T-V-V-V-R-V-E-R-R-F-A-H-P-I-L-Q-K-T-V-R-R-S-K-K-Y-K-A-H-D-E-N-N-Q-F-K-V-G-D-L-V-S-I-E-E-C-A-P-I-S-K-D-K-R-W-T-V-V-S-A-Q-S"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-Y-R-K-Q-F-K-G-R-I-K-G-V-A-K-G-G-S-D-L-A-F-G-E-F-G-L-K-A-Q-E-P-N-R-V-N-A-R-E-I-E-A-A-R-R-A-I-T-R-H-M-K-R-A-G-R-V-W-I-R-V-F-P-D-V-P-V-T-A-K-P-T-E-V-R-M-G-K-G-K-G-S-V-E-Y-W-A-C-K-V-K-P-G-R-M-M-F-E-I-D-G-V-N-E-E-L-A-R-E-A-L-R-L-G-A-A-K-L-S-V-K-T-R-F-V-Q-R-I-A-E"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-G-K-A-K-A-E-R-R-L-K-D-N-E-A-Q-A-V-A-R-T-I-R-V-S-P-Q-K-L-N-L-V-A-A-L-I-R-G-K-K-V-D-R-A-L-A-E-L-E-F-S-R-K-R-I-A-G-T-V-K-K-T-L-E-S-A-I-A-N-A-E-N-N-H-D-L-D-V-D-S-L-I-V-A-E-A-F-V-G-K-S-I-V-M-K-R-F-H-A-R-G-R-G-R-A-S-R-V-E-K-P-F-A-H-L-T-I-V-V-R-E-V-E-A-K-G-E-A-A"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-D-L-R-H-Y-D-V-I-V-S-P-S-I-T-E-K-S-T-L-V-S-E-Q-N-Q-V-V-F-N-V-A-K-G-A-S-K-P-E-I-K-A-A-V-E-A-L-F-G-V-K-V-T-A-V-N-T-L-V-R-K-G-K-L-K-R-F-R-G-F-A-G-K-Q-K-D-V-K-K-A-I-V-T-L-A-D-G-Q-S-I-D-V-S-T-G-L"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-N-G-Q-N-I-R-I-R-L-K-A-F-D-H-R-I-L-D-A-S-T-R-E-I-V-S-T-A-K-R-T-G-A-S-V-R-G-P-V-P-L-P-T-R-I-E-K-F-T-V-N-R-S-P-H-V-D-K-K-S-R-E-Q-F-E-M-R-T-H-K-R-L-L-D-I-V-D-P-T-P-Q-T-V-D-A-L-M-K-L-D-L-A-A-G-V-D-V-E-I-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-R-A-E-K-R-E-I-N-P-D-P-K-F-G-D-L-V-V-T-K-F-M-N-A-I-M-L-H-G-K-K-S-V-A-E-S-I-V-Y-G-A-F-D-A-V-Q-S-K-L-K-Q-E-P-V-A-V-F-H-S-A-L-D-N-I-A-P-H-V-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-D-V-R-P-E-R-R-Q-A-L-A-I-R-W-L-I-A-A-A-R-K-R-N-E-T-T-M-V-D-R-L-C-G-E-L-M-D-A-A-N-N-R-G-S-A-V-K-K-R-E-D-T-H-K-M-A-D-A-N-R-A-F-S-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-V-N-Q-L-I-R-K-P-R-Q-A-Q-V-K-R-N-K-V-P-A-L-Q-E-N-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-R-K-P-N-S-A-L-R-K-V-A-K-I-R-L-T-N-G-F-E-V-I-G-Y-I-P-G-E-G-H-N-L-Q-E-H-S-V-V-M-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-I-R-G-V-L-D-T-Q-G-V-K-N-R-K-Q-R-R-S-K-Y-G-A-K-R-P-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-D-L-A-K-I-V-E-D-L-S-S-L-T-V-L-E-A-A-E-L-S-K-L-L-E-E-K-W-G-V-S-A-A-A-P-V-A-V-A-A-A-G-G-A-A-G-A-A-A-P-V-E-E-E-K-T-E-F-D-V-I-L-T-D-A-G-A-N-K-I-N-V-I-K-E-V-R-A-I-T-G-L-G-L-K-E-A-K-D-L-V-E-G-A-P-K-A-V-K-E-A-V-S-K-A-E-A-A-D-L-K-K-K-L-E-D-A-G-A-K-V-D-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-E-R-A-E-K-R-E-F-V-T-E-L-N-E-V-F-K-A-S-G-S-V-V-V-A-H-Y-A-G-V-T-V-A-Q-M-N-D-F-R-S-K-M-R-A-A-G-G-T-V-R-V-A-K-N-R-L-A-K-I-A-L-Q-G-T-E-S-E-G-M-T-D-L-F-K-G-Q-T-L-I-A-F-S-E-D-P-V-T-A-P-K-V-V-M-D-F-A-K-T-N-D-K-L-V-V-L-G-G-A-M-G-A-T-T-L-N-A-E-G-V-K-S-L-A-T-L-P-S-L-D-E-L-R-A-K-L-L-G-L-I-N-A-P-A-T-R-V-A-T-V-V-A-A-P-A-S-Q-L-A-R-V-F-S-A-Y-A-K-K-D-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-A-G-Q-L-K-L-Q-V-K-A-G-S-A-N-P-S-P-P-I-G-P-A-L-G-Q-R-G-I-N-I-M-E-F-C-K-A-F-N-A-A-T-Q-E-M-E-K-G-M-P-I-P-V-V-I-T-Y-Y-Q-D-K-S-F-T-F-V-M-K-Q-P-P-V-S-Y-F-L-K-R-E-A-K-V-Q-A-G-S-K-T-P-G-K-A-K-A-G-S-I-S-K-A-Q-I-R-T-I-A-E-A-K-M-K-D-L-N-A-A-D-I-D-G-A-M-A-M-V-E-G-S-A-R-S-M-G-L-E-V-T-G"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-V-D-L-A-T-V-K-R-V-A-R-L-A-R-I-A-V-S-D-E-E-A-E-R-M-T-G-E-L-N-G-I-L-G-F-V-E-Q-L-S-E-V-D-V-D-G-V-E-P-M-T-S-V-M-P-M-K-M-K-K-R-D-D-I-V-A-D-G-D-K-A-D-D-I-V-A-N-A-P-N-S-D-R-N-F-F-L-V-P-K-V-V-E"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-I-L-T-M-E-E-L-A-E-R-L-P-P-Y-Q-S-V-A-G-L-D-L-G-T-K-T-I-G-I-S-V-S-D-L-G-R-R-F-A-T-P-R-E-V-I-R-R-V-K-F-G-A-D-A-Q-A-L-L-S-F-A-E-K-E-K-I-A-A-F-I-I-G-L-P-V-N-M-D-G-S-E-G-P-R-C-Q-A-T-R-A-F-V-R-N-M-G-E-K-T-D-I-P-F-V-L-W-D-E-R-L-S-T-V-A-A-E-R-V-L-I-E-M-D-V-S-R-K-K-R-A-E-R-I-D-S-A-A-A-S-F-I-L-Q-G-A-L-D-R-L-A-S-L-A-R-G-A-S-G-D-R-D-A-P"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-A-T-F-V-Q-K-P-A-E-V-E-K-K-W-I-L-I-D-A-E-G-L-V-V-G-R-L-A-S-L-I-A-N-R-L-R-G-K-H-K-A-T-Y-T-P-H-V-D-D-G-D-N-V-I-V-I-N-A-E-K-A-V-L-T-G-K-K-Y-T-D-K-K-Y-Y-W-H-T-G-Y-P-G-G-I-K-E-R-T-A-R-Q-I-I-E-G-R-F-P-E-R-V-I-E-K-A-V-E-R-M-V-P-R-G-P-L-G-R-R-Q-M-K-N-L-R-V-Y-A-G-S-N-H-P-H-E-A-Q-Q-P-A-V-L-D-V-A-K-L-N-S-K-N-T-R-S-A"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-S-G-K-T-V-T-R-A-D-L-A-E-S-V-F-R-K-V-G-L-S-R-T-E-S-A-E-L-V-E-T-V-I-D-E-I-C-N-A-I-V-R-G-E-S-V-K-L-S-S-F-A-T-F-Q-V-R-D-K-N-E-R-I-G-R-N-P-K-T-G-E-E-V-P-I-S-P-R-R-V-M-T-F-K-A-S-N-V-L-K-Q-R-V-L-K-A-H-L-S-R-K-S-K-L-K-P-S-N-P-A-G"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-T-N-T-P-S-D-Q-P-L-K-Q-V-N-Q-R-G-A-A-R-L-A-A-V-Q-A-L-Y-Q-M-D-V-G-G-T-G-V-L-E-I-V-A-E-Y-E-E-H-R-L-G-K-E-L-D-G-D-T-Y-L-R-A-D-A-S-W-F-R-S-I-V-A-G-V-V-R-D-Q-R-K-L-D-P-L-I-G-S-A-L-Q-D-D-W-A-L-S-R-L-D-S-T-V-R-A-I-L-R-A-G-T-F-E-I-L-E-R-K-D-V-P-V-P-V-I-V-T-E-Y-V-E-I-A-K-A-F-F-Q-D-E-E-P-K-L-V-N-A-V-L-D-R-I-A-K-Q-V-R-G-D-Q-R-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-A-K-I-K-P-V-H-I-L-I-V-E-A-R-F-Y-D-D-M-A-D-A-M-L-D-G-A-K-H-A-L-D-A-A-G-A-T-Y-D-I-V-T-V-P-G-A-L-E-I-P-A-A-I-A-M-A-L-D-G-A-D-E-G-G-A-E-Y-D-G-F-V-A-L-G-M-V-I-R-G-E-T-Y-H-F-D-I-V-A-N-E-S-A-R-A-L-M-D-L-A-V-S-E-S-L-A-L-G-N-G-I-L-T-V-E-N-D-E-Q-A-W-A-R-A-R-R-T-E-G-D-K-G-G-F-A-A-R-A-A-L-T-M-I-E-L-K-Q-R-L-G-A-E-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-L-Y-E-H-V-F-L-A-R-Q-D-I-T-P-Q-Q-V-D-A-L-V-E-Q-Y-K-G-V-I-E-A-N-G-G-K-V-G-R-V-E-N-W-G-L-K-S-L-T-Y-R-I-K-K-N-R-K-A-H-Y-V-L-M-D-I-D-A-P-A-P-A-V-H-E-V-E-R-Q-M-R-I-N-E-D-V-L-R-Y-M-T-I-A-V-G-K-H-E-E-G-P-S-A-M-M-Q-K-R-D-R-D-D-R-P-R-R-D-G-D-R-P-D-R-G-G-F-G-D-R-G-P-R-P-D-R-G-D-R-D-D-R-P-R-R-P-R-E-D-R-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-E-V-S-S-A-P-V-R-R-P-F-H-R-R-R-K-T-C-P-F-S-G-A-N-A-P-R-I-D-Y-K-D-V-R-L-L-Q-R-Y-I-S-E-R-G-K-I-V-P-S-R-I-T-A-V-S-Q-K-K-Q-R-E-L-A-Q-A-I-K-R-A-R-F-L-G-L-L-P-Y-I-V-S"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-V-I-L-L-E-R-I-A-K-L-G-Q-M-G-E-T-V-K-V-R-D-G-F-A-R-N-Y-L-L-P-L-G-K-A-L-R-A-N-A-A-N-K-A-R-F-E-S-E-R-S-T-L-E-A-R-N-L-E-R-K-S-E-A-Q-K-V-A-D-S-L-D-G-K-S-F-I-I-V-R-S-A-G-E-T-G-Q-L-Y-G-S-V-A-A-R-D-I-V-E-T-L-A-A-E-G-F-N-I-N-R-N-Q-V-D-L-N-Q-P-I-K-A-I-G-L-H-K-V-T-L-H-L-H-G-E-V-D-V-A-I-E-I-N-V-A-R-S-A-E-E-A-E-R-Q-A-K-G-E-S-L-T-S-A-D-A-I-Y-G-V-D-E-D-A-L-K-P-E-D-F-F-N-P-E-A-E-L-E-S-E-E-E"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-I-G-I-G-S-D-L-I-D-I-R-R-I-E-N-S-L-Q-R-F-G-E-R-F-V-N-R-C-F-T-D-I-E-I-A-K-S-E-G-R-K-N-R-A-A-S-Y-A-K-R-F-A-A-K-E-A-C-S-K-A-L-G-T-G-L-A-Q-G-V-F-W-K-D-M-G-V-V-N-L-P-G-G-K-P-T-M-Q-L-T-G-G-A-A-A-R-L-Q-E-M-L-P-V-G-H-R-A-A-I-H-L-T-I-T-D-D-F-P-L-A-Q-A-F-V-I-I-E-A-L-P-V-A-P-A-E-G-T-V"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-C-I-D-K-V-E-N-R-F-E-L-V-L-L-A-S-H-R-A-R-L-V-S-Q-G-A-P-I-T-V-D-R-D-N-D-K-N-P-V-V-A-L-R-E-I-A-D-E-T-L-S-P-G-D-L-K-E-D-L-I-H-S-L-Q-K-H-V-E-V-D-E-P-E-P-D-P-A-S-L-V-Q-T-E-A-A-P-A-F-A-E-A-A-E-E-E-D-Q-P-E-A-L-T-F-D-R-M-S-E-E-E-L-L-A-G-I-E-G-L-V-P-P-E-K-S-D-D-Y"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-P-K-G-S-E-R-T-V-K-K-V-V-A-E-N-R-K-A-R-F-N-Y-E-I-V-D-T-Y-E-A-G-L-V-L-T-G-T-E-V-K-S-L-R-E-G-K-A-N-I-A-E-S-Y-A-T-D-E-G-G-E-I-W-L-I-N-S-Y-L-P-E-Y-L-Q-A-N-R-F-N-H-E-T-R-R-R-R-K-L-L-L-S-K-R-E-V-N-R-L-Q-G-A-V-N-R-E-G-M-S-L-I-P-L-R-I-Y-F-N-E-R-G-R-V-K-L-E-L-A-L-G-K-G-K-K-L-H-D-K-R-E-T-S-K-E-R-D-W-N-R-Q-K-N-R-L-L-K-E-R-G"} +{"text": "### FUNCTION Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I ### SEQUENCE -M-A-D-N-G-Q-A-D-R-K-E-R-S-N-G-V-I-V-G-T-C-L-A-F-V-A-G-M-I-G-M-A-Y-A-A-V-P-L-Y-D-M-F-C-R-V-T-G-Y-N-G-T-T-Q-R-V-E-Q-A-S-D-L-I-L-D-E-K-I-K-V-T-F-D-A-N-V-A-A-G-L-P-W-E-F-V-P-V-Q-R-D-I-D-V-R-I-G-E-T-V-Q-I-M-Y-R-A-K-N-L-A-S-T-P-T-T-G-Q-A-T-F-N-V-T-P-M-A-A-G-A-Y-F-N-K-V-Q-C-F-C-F-T-E-T-T-L-E-P-G-E-E-M-E-M-P-V-V-F-F-V-D-P-E-I-V-K-P-V-E-T-Q-G-I-K-T-L-T-L-S-Y-T-F-Y-P-R-E-P-S-K-P-V-A-Q-V-K-A-K-A-E-N-K-L"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-N-N-N-A-Q-P-D-V-S-A-L-S-F-E-Q-A-V-E-E-L-E-R-I-V-S-A-L-E-R-G-D-V-A-L-D-K-S-I-E-I-Y-E-R-G-E-A-L-K-K-H-C-E-A-L-L-K-A-A-E-D-R-I-E-K-I-R-L-D-R-A-G-R-P-Q-G-V-E-P-L-D-A-E"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-L-D-A-T-F-Y-A-L-V-G-L-I-L-F-F-V-L-I-A-Y-L-K-V-P-G-M-V-G-K-A-L-D-A-R-A-D-K-I-S-N-E-L-A-E-A-K-R-L-R-E-E-A-Q-S-L-V-A-E-Y-Q-R-K-R-K-D-A-E-A-E-A-A-S-I-V-A-A-A-Q-R-E-A-E-M-L-T-A-E-A-K-Q-K-T-E-E-Y-V-A-R-R-T-A-L-S-E-Q-K-I-K-Q-A-E-S-D-A-I-N-A-V-R-A-A-A-V-D-L-A-I-S-A-A-E-K-V-L-A-S-K-A-D-A-G-A-Q-E-T-L-F-K-K-A-I-G-E-V-K-A-R-L-N"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-N-T-E-A-A-G-R-R-V-H-V-I-Q-G-E-F-K-V-V-N-D-P-D-I-V-L-S-T-I-L-G-S-C-V-A-A-C-M-R-D-P-A-A-G-V-G-G-M-N-H-F-L-L-P-G-S-A-T-S-P-S-S-G-A-D-A-T-R-Y-G-V-H-L-M-E-L-L-I-N-G-L-L-K-Q-G-A-R-R-D-R-L-E-A-K-I-F-G-G-A-R-T-I-A-R-F-S-N-V-G-E-Q-N-A-A-F-A-R-Q-F-L-M-D-E-G-I-R-I-V-G-E-S-T-G-G-D-H-G-R-K-L-E-Y-W-P-S-S-G-R-A-R-Q-Y-A-L-T-G-V-E-A-Q-R-A-L-Q-M-D-Q-R-P-A-V-P-K-P-A-E-S-P-I-E-F-F"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-R-G-G-G-K-K-N-G-S-N-V-E-P-L-R-A-T-R-P-C-A-E-C-G-R-P-S-V-R-E-H-Y-P-F-C-S-E-R-C-R-N-V-D-L-N-R-W-L-S-G-S-Y-A-I-P-V-A-D-D-E-S-K-A-D-D-G-D-E-R"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-V-L-E-F-P-G-V-V-T-E-L-L-P-N-A-T-F-R-V-K-L-E-N-E-H-E-I-I-A-H-T-A-G-R-M-R-K-N-R-I-R-V-L-A-G-D-K-V-L-V-E-M-T-P-Y-D-L-T-K-G-R-I-T-Y-R-F-K"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-N-E-F-K-E-F-I-A-R-G-N-V-M-D-L-A-V-G-V-I-I-G-A-A-F-S-K-I-V-D-S-V-V-N-D-L-V-M-P-V-V-G-A-I-T-G-G-G-F-D-F-S-N-Y-F-L-P-L-S-A-S-V-T-A-P-T-L-S-A-A-R-E-Q-G-A-V-F-A-Y-G-N-F-I-T-V-L-I-N-F-L-I-L-A-W-I-I-F-L-L-I-K-L-V-N-R-A-R-A-S-V-E-R-D-K-A-P-D-P-A-A-P-P-P-Q-D-I-L-L-L-S-E-I-R-D-L-L-R-Q-R-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-T-T-D-K-D-K-M-A-V-G-R-L-K-S-R-P-Q-F-L-A-V-R-A-G-E-S-R-R-G-P-L-F-L-L-E-V-L-D-R-N-D-P-E-G-E-A-R-V-G-F-T-V-T-K-K-H-G-N-A-V-E-R-N-R-M-R-R-R-L-K-E-A-V-R-L-S-A-G-F-A-M-K-P-G-H-D-Y-V-I-V-A-R-R-D-L-L-N-A-P-F-D-A-L-T-R-A-L-R-D-R-I-E-N-K-P-K-Q-K-R-P-P-A-G-S-R-K-S"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-A-L-D-I-Q-I-S-V-E-A-G-D-W-P-P-E-D-E-L-Q-S-F-C-E-R-V-L-E-A-A-A-D-F-L-A-R-E-E-N-Q-P-L-P-A-Q-A-A-E-L-S-L-V-F-T-D-D-Q-S-I-R-A-I-N-A-E-W-R-G-Q-D-K-A-T-N-V-L-S-F-P-A-F-P-V-T-P-G-R-M-P-G-P-M-L-G-D-I-V-V-A-H-E-T-L-R-R-E-A-A-E-L-E-K-P-F-D-A-H-L-T-H-L-L-V-H-G-F-L-H-L-F-G-Y-D-H-I-E-D-D-E-A-E-R-M-E-G-L-E-T-R-I-L-A-R-L-G-L-S-D-P-Y-G-D-Q-P-P-H"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-I-K-S-E-L-V-Q-I-V-A-A-R-N-P-H-L-Y-H-R-D-V-E-N-I-V-N-A-V-L-D-E-I-T-D-A-L-A-A-G-N-R-V-E-L-R-G-F-G-A-F-S-V-K-N-R-P-S-R-S-G-R-N-P-R-T-G-D-S-V-F-V-E-E-K-W-V-P-F-F-K-T-G-K-E-L-R-E-R-L-N-P-G-M-N-D-N-N-N-G-E-D-D"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-T-S-H-A-K-H-K-K-T-L-K-A-A-K-G-F-Y-G-R-R-K-N-T-I-R-A-A-K-A-A-V-D-R-S-K-Q-F-A-Y-R-D-R-K-V-N-K-R-N-F-R-A-L-W-I-Q-R-I-N-A-A-V-R-E-F-G-L-T-Y-G-R-F-I-D-G-L-N-K-A-G-I-E-V-D-R-K-V-L-S-D-M-A-I-H-E-P-A-A-F-G-A-L-V-E-A-S-K-K-A-L-A-Y-L-K-E-A-G-T-A-N-E-F-E-S-A-V-R"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-R-R-P-F-K-A-D-A-P-V-K-E-G-P-R-A-N-K-E-I-R-V-P-R-V-Q-L-I-D-A-E-Q-N-L-G-S-I-P-I-D-Q-A-L-R-M-A-D-E-A-G-L-D-L-V-E-I-A-P-N-S-D-P-P-V-C-K-I-L-D-L-G-K-L-K-Y-A-N-Q-K-K-A-A-E-A-R-K-K-Q-K-I-V-E-I-K-E-I-K-M-R-P-N-I-D-T-H-D-Y-E-V-K-M-K-A-M-N-R-F-F-E-E-G-D-K-V-K-V-T-L-K-F-R-G-R-E-M-A-H-Q-E-L-G-M-K-L-L-M-Q-V-K-D-D-T-Q-E-I-A-K-V-E-A-E-P-K-L-E-G-R-Q-M-M-M-V-L-A-P-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-K-V-I-A-S-S-V-R-K-G-N-V-L-D-V-D-G-K-L-Y-V-V-L-T-A-Q-N-F-H-P-G-K-G-T-P-V-T-Q-V-D-M-R-R-I-S-D-G-V-K-V-S-E-R-Y-R-T-T-E-Q-V-E-R-A-F-V-E-D-R-E-H-T-F-L-Y-E-D-G-E-G-F-H-F-M-N-P-E-T-Y-D-Q-L-V-M-S-S-E-D-I-G-D-L-K-A-Y-L-Q-E-G-M-A-V-M-L-S-I-H-E-G-I-A-I-A-I-D-L-P-R-H-V-T-L-E-I-T-E-T-E-P-V-V-K-G-Q-T-A-S-S-S-Y-K-P-A-V-L-S-N-G-V-R-T-L-V-P-P-H-I-Q-A-G-T-R-V-V-I-A-T-E-D-G-S-Y-V-E-R-A-K-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-V-T-A-E-R-K-A-Q-I-I-K-E-F-A-T-V-E-G-D-T-G-S-P-E-V-Q-V-A-I-L-T-E-R-I-N-N-L-T-E-H-F-K-D-H-K-K-D-N-H-S-R-R-G-L-L-A-L-V-S-S-R-R-S-L-L-D-Y-L-K-K-K-D-E-A-R-Y-T-K-L-I-G-A-L-G-I-R-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-S-T-S-S-A-P-S-Q-R-M-L-R-V-G-E-Q-V-R-A-A-I-T-Q-V-L-Q-R-G-E-V-L-D-P-L-I-E-N-T-V-I-S-I-S-E-V-R-M-S-P-D-L-K-I-A-T-A-Y-V-T-P-L-G-V-A-D-H-A-A-V-I-E-A-L-N-K-H-A-K-F-I-R-G-R-L-G-P-Q-L-R-Q-M-K-Y-M-P-D-V-R-F-R-D-D-T-S-F-D-N-Y-Q-K-I-D-S-L-L-R-S-P-E-V-S-R-D-L-D-R-D-A-D-D-E-E"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-R-D-I-M-G-M-M-G-K-V-K-E-M-Q-A-K-M-E-K-M-Q-A-E-I-A-A-L-E-I-D-G-T-S-G-G-G-L-V-T-V-R-L-D-G-K-G-H-M-K-S-L-K-V-D-P-S-L-F-K-E-D-D-V-E-I-L-E-D-L-I-V-A-A-H-K-D-A-K-D-K-A-E-A-V-Q-A-E-K-T-R-E-L-T-A-G-L-P-I-P-P-G-M-K-L-P-F"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-A-D-R-K-C-L-A-L-I-A-H-D-Q-K-K-D-D-L-A-A-F-A-K-A-N-E-A-V-L-S-K-W-K-I-V-A-T-G-T-T-G-G-R-V-L-D-V-C-P-A-L-D-I-V-R-L-K-S-G-P-L-G-G-D-Q-Q-I-G-A-L-I-A-T-G-D-V-D-C-L-I-F-F-V-D-P-L-T-A-M-P-H-D-V-D-V-K-A-L-M-R-L-A-I-V-Y-D-I-P-M-A-L-N-R-A-T-A-E-Q-L-I-D-F-R-R-N"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-T-T-D-T-A-S-N-G-N-G-S-A-Q-Q-Q-S-P-S-L-N-I-L-A-Q-Y-V-K-D-L-S-F-E-N-P-G-A-P-R-S-L-Q-A-R-D-R-S-P-S-I-N-I-N-V-N-V-N-A-N-P-L-A-E-N-D-F-D-V-V-L-S-L-S-A-Q-A-K-D-G-D-K-M-L-F-N-V-E-L-A-Y-G-G-V-F-R-V-A-G-F-P-Q-E-H-M-L-P-L-L-F-I-E-C-P-R-L-L-F-P-F-A-R-Q-I-V-A-D-A-T-R-N-G-G-F-P-P-L-M-I-D-P-I-D-F-A-Q-M-F-A-Q-R-M-A-E-E-K-V-R-A-Q-V-A-N-T-N-D-T-A-N"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-K-P-L-L-I-L-A-S-A-S-P-F-R-R-A-L-L-S-N-A-G-L-A-F-E-A-R-A-A-A-I-D-E-R-A-L-E-Q-P-L-E-A-S-G-A-S-P-A-D-V-A-L-A-L-A-E-A-K-A-K-D-V-A-R-Y-F-S-D-A-L-V-I-G-S-D-Q-T-M-S-L-G-T-R-V-Y-H-K-P-R-D-M-T-E-A-A-E-H-L-R-S-L-S-G-R-M-H-S-L-N-S-A-I-V-L-V-R-N-D-E-V-V-W-R-H-V-S-T-A-N-M-T-V-R-P-L-S-D-G-F-I-D-R-H-L-A-K-V-G-E-K-A-L-T-S-V-G-A-Y-Q-L-E-G-E-G-I-Q-L-F-E-R-I-E-G-D-Y-F-T-I-L-G-L-P-M-L-P-L-L-S-K-L-R-E-L-G-A-I-D-A"} +{"text": "### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate -ureidoglycolate, generating urea and glyoxylate Involved in the utilization of allantoin as nitrogen source ### SEQUENCE -M-I-P-L-P-I-R-P-L-S-H-S-E-F-A-P-F-G-D-V-I-E-P-D-D-A-K-S-F-P-I-N-A-G-K-C-I-R-Y-H-D-L-A-R-V-E-T-S-G-P-E-A-R-T-L-V-S-L-L-K-G-E-P-Y-D-I-P-L-T-L-K-M-V-E-R-H-P-L-G-S-Q-A-F-I-P-L-T-G-N-P-F-L-V-V-V-A-P-D-E-G-G-E-P-G-E-P-I-A-F-E-T-G-P-G-Q-G-V-N-I-A-Q-N-V-W-H-G-I-L-T-P-L-R-S-T-S-E-F-V-V-I-D-R-G-G-S-G-C-N-L-E-E-H-F-F-E-K-P-Y-Q-V-E-Y-A"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-I-F-R-F-F-S-K-Q-T-S-A-P-T-A-R-E-R-L-Q-V-L-L-A-H-E-R-A-S-V-G-Q-S-D-L-V-A-V-L-R-E-E-I-L-A-V-I-A-K-H-V-Q-V-D-R-D-K-V-N-V-T-M-E-R-G-E-H-V-T-T-L-E-V-D-I-E-I-P-M-K-A-G-V-R-A-A"} +{"text": "### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate -ureidoglycolate, generating urea and glyoxylate Involved in the utilization of allantoin as nitrogen source ### SEQUENCE -M-S-H-M-L-S-I-E-P-L-T-R-E-A-F-A-P-F-G-S-V-I-E-A-D-P-A-S-M-R-F-I-N-G-G-N-T-E-R-F-H-A-L-A-R-V-D-A-A-G-E-G-A-G-V-I-I-N-I-F-R-G-Q-P-R-V-F-P-Y-S-V-T-M-M-E-R-H-P-L-G-S-Q-S-F-S-P-L-R-D-R-P-W-L-V-V-V-A-E-D-Q-G-D-R-P-G-R-P-R-V-F-I-A-D-G-R-Q-G-V-N-Y-G-R-N-V-W-H-H-P-L-M-S-V-G-A-V-S-E-F-I-V-V-D-R-E-G-P-G-N-N-L-E-E-F-H-Y-D-E-A-F-V-I-P-D-P-S-S-E-E-L-R"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 5-hydroxyisourate ### SEQUENCE -M-S-K-S-G-R-L-T-T-H-V-L-D-T-A-L-G-R-P-A-H-G-L-K-I-D-L-Y-R-L-E-G-D-A-R-H-L-I-R-T-V-H-T-N-S-D-G-R-V-D-G-P-L-M-E-G-A-G-F-A-T-G-T-Y-E-L-V-F-H-A-G-D-Y-F-R-S-A-G-V-K-L-P-D-P-A-F-L-E-L-V-P-L-R-F-G-I-A-D-A-D-S-H-Y-H-V-P-L-L-L-S-P-Y-G-Y-S-T-Y-R-G-S"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 5-hydroxyisourate ### SEQUENCE -M-Q-V-Q-D-G-T-P-G-R-L-T-T-H-V-L-D-T-A-S-G-R-P-A-S-N-L-R-I-D-L-Y-R-I-E-G-E-R-P-E-L-L-S-S-T-R-T-N-D-D-G-R-C-D-A-P-L-L-N-G-S-T-M-E-T-G-T-Y-E-L-R-F-H-A-G-E-Y-L-G-T-A-A-E-R-G-A-N-P-F-L-D-V-I-P-I-R-F-G-I-A-D-R-A-A-H-Y-H-V-P-L-L-L-S-P-Y-G-Y-S-T-Y-R-G-S"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-L-N-Q-L-R-P-A-L-V-L-T-F-A-L-T-L-I-T-G-L-G-Y-P-L-L-I-T-G-V-A-Q-A-L-M-P-A-E-A-N-G-S-L-V-R-K-G-S-V-L-I-G-S-Q-L-I-G-Q-N-F-A-S-E-K-Y-F-W-P-R-P-S-A-T-G-P-E-P-Y-N-A-V-A-S-S-G-S-N-L-G-T-T-S-D-K-L-K-E-R-V-A-A-D-I-E-R-L-R-A-A-G-I-G-G-E-I-P-A-D-A-G-M-A-S-G-S-G-L-D-P-H-I-S-P-E-F-A-R-V-Q-I-A-R-V-A-K-A-R-G-L-P-E-A-G-V-D-A-L-V-D-R-A-T-Q-G-R-L-F-G-L-I-G-E-P-R-V-N-V-L-E-L-N-L-A-L-D-A-P-R-T"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-T-K-R-A-V-L-A-G-G-C-F-W-G-M-Q-D-L-I-R-K-L-P-G-V-I-E-T-R-V-G-Y-T-G-G-D-V-P-N-A-T-Y-R-N-H-G-T-H-A-E-G-I-E-I-I-F-D-P-E-R-I-S-Y-R-R-I-L-E-L-F-F-Q-I-H-D-P-T-T-K-D-R-Q-G-N-D-I-G-T-S-Y-R-S-A-I-Y-Y-V-D-D-E-Q-K-R-I-A-Q-E-T-I-A-D-V-E-A-S-G-L-W-P-G-K-V-V-T-E-V-E-P-V-R-D-F-W-E-A-E-P-E-H-Q-N-Y-L-E-R-Y-P-N-G-Y-T-C-H-F-P-R-P-N-W-V-L-P-R-R-S-A-A-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-S-T-D-F-R-P-L-H-D-R-V-V-V-R-R-V-E-S-E-E-K-T-K-G-G-V-I-I-P-D-T-A-K-E-K-P-Q-E-G-E-I-V-A-V-G-S-G-A-R-D-E-S-G-K-V-V-P-L-D-V-K-A-G-D-R-I-L-F-G-K-W-S-G-T-E-V-K-I-N-G-E-D-L-L-I-M-K-E-A-D-I-M-G-V-I-G"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-T-F-R-P-L-L-D-R-V-V-I-R-R-A-E-G-N-T-Q-S-K-G-G-I-I-I-P-D-T-A-K-E-K-P-Q-E-G-E-V-I-A-V-G-P-G-S-R-D-E-S-G-K-L-I-P-L-D-V-K-I-G-D-T-I-L-F-G-K-W-S-G-T-E-V-K-I-D-G-E-D-L-L-I-M-K-E-S-D-I-M-G-I-V-A-N-T-V-P-T-A-A-N-A-A"} +{"text": "### FUNCTION May have a role in the cell cycle ### SEQUENCE -M-S-H-T-I-L-L-V-Q-P-G-R-N-P-E-T-R-T-Y-S-D-Y-E-S-V-N-E-C-M-E-G-V-C-K-I-Y-E-E-H-L-K-R-R-N-P-N-T-P-T-I-T-Y-D-I-S-Q-L-F-D-F-V-D-Q-L-A-D-L-S-C-L-V-Y-Q-K-S-T-N-T-Y-A-P-Y-N-K-E-W-I-K-E-K-I-Y-V-L-L-R-Q-A-A-G-T-T-D"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-K-Q-K-I-R-I-R-L-K-A-Y-D-H-R-V-I-D-Q-S-A-E-K-I-V-E-T-A-K-R-S-G-A-D-V-S-G-P-I-P-L-P-T-E-K-S-V-Y-T-I-I-R-A-V-H-M-Y-K-D-S-R-E-Q-F-E-Q-R-T-H-K-R-L-I-D-I-V-N-P-T-P-K-T-V-D-A-L-M-G-L-N-L-P-S-G-V-D-I-E-I-K-L"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-L-N-R-T-I-L-V-G-R-L-T-R-D-P-E-L-R-T-T-Q-S-G-V-N-V-A-S-F-T-L-A-V-N-R-T-F-T-N-A-Q-G-E-R-E-A-D-F-I-N-I-I-V-F-K-K-Q-A-E-N-V-N-K-Y-L-S-K-G-S-L-A-G-V-D-G-R-L-Q-T-R-N-Y-E-N-K-E-G-Q-R-V-Y-V-T-E-V-I-A-D-S-I-Q-F-L-E-P-K-N-S-N-D-T-Q-Q-D-L-Y-Q-Q-Q-V-Q-Q-T-R-G-Q-S-Q-Y-S-N-N-K-P-V-K-D-N-P-F-A-N-A-N-G-P-I-E-L-N-D-D-D-L-P-F"} +{"text": "### FUNCTION Involved in countering the first line of host defense mechanisms Efficiently inhibits opsonization, phagocytosis and killing of Saureus by human neutrophils Acts by binding and stabilizing human C3 convertases ### SEQUENCE -M-K-I-R-K-S-I-L-A-G-T-L-A-I-V-L-A-S-P-L-V-T-N-L-D-K-N-E-A-Q-A-S-T-S-L-P-T-S-N-E-Y-Q-N-E-K-L-A-N-E-L-K-S-L-L-D-E-L-N-V-N-E-L-A-T-G-S-L-N-T-Y-Y-K-R-T-I-K-I-S-G-Q-K-A-M-Y-A-L-K-S-K-D-F-K-K-M-S-E-A-K-Y-Q-L-Q-K-I-Y-N-E-I-D-E-A-L-K-S-K-Y"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-A-V-F-K-V-F-Y-Q-H-N-R-D-E-V-I-V-R-E-N-T-Q-S-L-Y-V-E-A-Q-T-E-E-Q-V-R-R-Y-L-K-D-R-N-F-N-I-E-F-I-T-K-L-E-G-A-H-L-D-Y-E-K-E-N-S-E-H-F-N-V-E-I-A-K"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-S-K-L-I-D-S-F-M-K-L-P-G-I-G-P-K-T-A-Q-R-L-A-F-H-T-L-D-M-K-E-D-D-V-V-Q-F-A-K-A-L-V-D-V-K-R-E-L-T-Y-C-S-V-C-G-H-I-T-E-N-D-P-C-Y-I-C-E-D-K-Q-R-D-R-S-V-I-C-V-V-E-D-D-K-D-V-I-A-M-E-K-M-R-E-Y-K-G-L-Y-H-V-L-H-G-S-I-S-P-M-D-G-I-G-P-E-D-I-N-I-P-S-L-I-E-R-L-K-S-D-E-V-S-E-L-I-L-A-M-N-P-N-L-E-G-E-S-T-A-M-Y-I-S-R-L-V-K-P-I-G-I-K-V-T-R-L-A-Q-G-L-S-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-I-T-G-R-T-E-M"} +{"text": "### FUNCTION Transcriptional repressor that constitutively blocks the transcription of the gene for the penicillin-binding protein MecA Binds DNA as a dimer ### SEQUENCE -M-D-N-K-T-Y-E-I-S-S-A-E-W-E-F-M-N-I-I-W-M-K-K-Y-A-S-A-N-N-I-I-E-E-I-Q-M-Q-K-D-W-S-P-K-T-I-R-T-L-I-T-R-L-Y-K-K-G-F-I-D-R-K-K-D-N-K-I-F-Q-Y-Y-S-L-V-E-E-S-D-I-K-Y-K-T-S-K-N-F-I-N-K-V-Y-K-G-G-F-N-S-L-V-L-N-F-V-E-K-E-D-L-S-Q-D-E-I-E-E-L-R-N-I-L-N-K-K"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-I-Y-K-D-I-F-T-D-D-E-L-S-S-D-S-F-P-M-K-L-V-D-D-L-V-Y-E-F-K-G-K-H-V-V-R-K-E-G-E-I-V-L-A-G-S-N-P-S-A-E-E-G-A-E-D-D-G-S-D-E-H-V-E-R-G-I-D-I-V-L-N-H-K-L-V-E-M-N-C-Y-E-D-A-S-M-F-K-A-Y-I-K-K-F-M-K-N-V-I-D-H-M-E-K-N-N-R-D-K-A-D-V-D-A-F-K-K-K-I-Q-G-W-V-V-S-L-L-A-K-D-R-F-K-N-L-A-F-F-I-G-E-R-A-A-E-G-A-E-N-G-Q-V-A-I-I-E-Y-R-D-V-D-G-T-E-V-P-T-L-M-L-V-K-E-A-I-I-E-E-K-C"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-A-V-T-Y-E-K-T-F-E-I-E-I-I-N-E-L-S-E-S-V-Y-N-R-V-L-N-Y-V-L-N-H-E-L-D-T-K-N-T-R-L-L-E-V-N-L-L-N-Q-L-E-V-A-Q-E-V-D-L-F-Q-Q-P-F-E-E-L-Q-A-I-H-E-Y-W-R-S-M-N-Q-Y-S-K-Q-I-L-T-K-E-K-V-A"} +{"text": "### FUNCTION Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-H-T-S-E-M-L-K-H-V-Y-D-I-N-L-S-Y-L-L-L-A-Q-R-L-I-S-Q-D-K-P-S-A-M-F-R-L-G-I-S-E-E-M-A-T-T-L-G-G-L-T-L-P-Q-M-V-K-L-A-E-T-N-Q-L-V-C-Q-F-R-F-D-S-H-Q-T-I-T-R-L-T-Q-D-S-R-V-D-D-L-Q-Q-I-H-T-G-I-L-L-S-T-R-L-L-T-E-V-S-Q-T-D-E-V-A-R-K-K-R-A"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-T-G-R-V-W-V-F-G-D-S-L-N-T-D-A-M-Y-P-P-D-A-M-K-L-D-V-A-A-A-A-K-M-V-F-Y-Q-V-R-P-G-W-T-D-E-V-Q-R-G-D-I-V-V-A-G-N-N-F-G-L-G-S-S-R-P-V-A-A-L-F-N-E-L-G-V-A-A-L-V-A-E-E-F-N-S-L-F-F-R-N-A-V-N-A-G-L-P-A-M-T-V-P-G-V-T-E-A-F-S-D-G-D-I-G-T-F-D-L-G-T-G-E-W-H-N-D-T-T-G-A-G-G-T-V-P-V-L-P-D-L-I-L-D-I-L-A-G-G-G-V-L-P-R-L-A-E-R-G-Y-L-P-A-E-L-A-E-T-L-R-S-A-A-V-A-V-A-G-S-G-G-G-A"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-P-L-G-V-P-S-V-P-Y-R-L-P-G-S-Q-Y-E-R-W-I-D-I-Y-T-R-L-S-Q-E-R-I-I-F-L-G-Q-E-V-T-D-G-L-A-N-R-I-V-A-F-L-L-Y-L-D-S-E-D-P-G-K-P-I-Y-L-Y-I-N-S-P-G-G-S-V-T-A-G-M-A-I-Y-D-T-M-Q-Y-I-K-S-D-V-I-T-I-C-V-G-L-A-A-S-M-G-A-F-L-L-A-S-G-T-P-G-K-R-L-A-L-P-H-A-R-I-M-I-H-Q-P-M-G-G-T-G-R-R-Q-A-T-D-I-Q-I-E-A-N-E-I-L-R-I-R-Q-Q-L-N-E-I-L-A-H-K-T-G-Q-T-I-E-K-I-Q-K-D-T-D-R-D-Y-Y-M-S-A-E-E-A-Q-A-Y-G-L-I-D-K-V-I-E-D-R-T-I"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-G-G-A-Q-E-L-L-L-S-R-I-R-D-V-P-D-Y-P-Q-P-G-V-V-F-K-D-I-T-P-L-L-A-D-P-E-A-F-S-V-L-T-E-A-L-A-E-V-C-V-R-H-G-A-T-K-V-V-G-L-E-A-R-G-F-I-L-G-A-P-V-A-V-R-A-G-L-G-F-I-P-I-R-K-A-G-K-L-P-G-A-T-L-S-Q-A-Y-A-L-E-Y-G-T-A-E-I-E-V-H-A-E-D-L-T-P-D-D-R-V-M-V-I-D-D-V-L-A-T-G-G-T-A-A-A-A-M-E-L-I-R-R-G-G-A-D-V-A-G-L-A-V-L-M-E-L-G-F-L-G-G-R-A-R-L-E-P-T-L-A-A-L-E-A-L-L-A-L"} +{"text": "### FUNCTION Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane Generates a proton motive force ### SEQUENCE -G-S-A-G-L-G-A-L-V-L-F-A-A-Y-A-N-D-L-S-Y-F-A-A-N-G-D-T-Y-P-Y-F-K-D-I-G-E-I-S-F-S-L-A-N-P-Y-V-V-A-G-L-L-F-G-G-L-I-P-Y-L-F-G-G-I-A-M-T-A-V-G-K-A-A-S-A-I-V-E-E-V-R-R-Q-F-R-E-K-P-G-I-M-A-G-T-E-K-P-D-Y-G-R-A-V-D-L-L-T-K-A-A-I-R-E-M-V-I-P-S-L-L-P-V-L-A-P-L-V-V-Y-F-G-V-L-L-I-S-G-S-K-A-F-A-F-A-A-L-G-A-Y-L-L-A-V-I-M-N-R-V-L-V-A-I-C-M-T-L-V-G-S-S"} +{"text": "### FUNCTION Involved in the temperature-dependent positive control of flagellum-driven swimming motility and cellular aggregation Regulates fliC expression by directly interacting with fliC promoter ### SEQUENCE -M-A-L-R-N-K-A-F-H-Q-L-R-Q-L-F-Q-Q-H-T-A-R-W-Q-H-E-L-P-D-L-T-K-P-Q-Y-A-V-M-R-A-I-A-D-K-P-G-I-E-Q-V-A-L-I-E-A-A-V-S-T-K-A-T-L-A-E-M-L-A-R-M-E-N-R-G-L-V-R-R-E-H-D-A-A-D-K-R-R-R-F-V-W-L-T-A-E-G-E-K-V-L-A-A-A-I-P-I-G-D-S-V-D-E-E-F-L-G-R-L-S-A-E-E-Q-E-L-F-M-Q-L-V-R-K-M-M-N-T"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-N-I-I-E-G-A-I-T-A-P-H-A-N-V-A-I-I-V-S-R-F-N-S-F-I-N-D-S-L-L-S-G-A-L-D-A-L-Q-R-Q-G-L-V-K-E-S-N-I-T-V-V-R-C-P-G-A-Y-E-L-P-L-L-A-Q-Q-L-A-K-K-G-S-Y-D-A-I-I-A-L-G-S-V-I-R-G-G-T-P-H-F-E-Y-V-A-G-E-C-N-K-G-L-A-Q-I-A-L-E-H-Q-I-P-V-A-F-G-V-L-T-V-D-S-I-E-Q-A-I-E-R-A-G-T-K-M-G-N-K-G-A-E-A-A-L-S-A-L-E-M-I-N-V-L-A-E-I-E-P"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-I-I-E-T-G-G-K-Q-I-K-V-E-E-G-Q-E-I-F-V-E-K-L-D-V-N-E-G-D-T-F-T-F-D-K-V-L-F-V-G-G-D-S-V-K-V-G-A-P-T-V-E-G-A-T-V-T-A-T-V-N-K-Q-G-R-G-K-K-I-T-V-F-T-Y-K-R-R-K-N-S-X-R-K-K-G-H-R-Q-P-Y-T-K-L-T-I-D-K-I-N-A"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-I-R-V-A-K-E-E-E-K-T-V-G-G-I-V-L-A-S-V-A-K-E-K-P-Q-T-G-E-V-I-A-V-G-E-G-R-V-L-E-N-G-T-K-V-P-M-E-V-K-I-G-D-T-V-M-F-E-K-Y-S-G-T-E-V-K-Y-E-G-V-E-Y-L-I-V-S-A-K-D-I-I-A-T-V-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-K-R-K-E-V-E-T-K-S-A-G-G-I-V-L-T-G-S-A-A-A-K-S-T-R-G-E-I-I-A-V-G-K-G-H-I-L-E-K-G-T-V-Q-P-L-D-V-K-V-G-D-I-V-I-F-N-D-G-Y-G-V-K-S-E-K-I-D-N-E-E-V-L-I-M-S-E-S-D-I-L-A-I-V-E-A"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-Q-P-I-G-D-R-V-I-V-K-V-K-E-E-E-E-K-T-V-G-G-I-V-L-A-S-N-A-K-Q-K-P-T-E-G-E-V-V-A-V-G-E-G-A-Y-T-S-N-G-D-K-L-P-M-V-V-K-K-G-D-V-V-L-Y-D-K-Y-S-G-T-N-V-E-Y-E-G-E-K-Y-L-V-L-H-E-K-D-I-L-A-I-E-K"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-L-I-E-V-S-E-E-E-E-K-T-V-G-G-I-V-L-A-S-T-A-Q-E-K-P-Q-T-G-K-V-V-A-V-G-P-G-R-T-L-D-N-G-E-L-A-T-V-P-V-N-V-G-D-T-V-L-F-E-K-Y-A-G-S-E-V-K-Y-D-G-Q-D-Y-M-I-F-S-A-K-D-L-V-A-I-V-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-S-I-R-P-L-H-D-R-V-I-V-K-R-K-D-A-E-S-K-S-E-G-G-I-V-L-M-G-S-A-T-E-K-S-T-R-A-E-V-I-A-V-G-N-G-R-I-L-E-N-G-E-V-R-P-L-D-V-K-V-G-D-Q-V-I-F-S-E-G-Y-G-V-K-T-E-K-I-D-G-E-E-V-L-I-L-S-E-S-D-I-L-A-I-V-E"} +{"text": "### FUNCTION Acyl carrier protein ### SEQUENCE -M-P-E-T-T-T-T-A-L-D-K-E-Q-L-R-E-L-V-A-D-V-L-D-L-D-V-A-E-V-T-D-D-A-D-F-M-E-D-L-D-V-D-S-L-M-A-L-E-I-T-V-R-L-E-K-E-Y-G-V-R-L-A-E-A-E-L-T-S-I-T-S-L-Q-G-T-Y-E-L-L-T-S-K-L-G-D-T-R"} +{"text": "### FUNCTION Acyl carrier protein ### SEQUENCE -M-T-T-G-L-D-A-A-R-K-Q-E-I-K-E-I-V-C-D-I-L-E-I-D-E-D-E-V-T-E-T-S-L-F-K-E-Q-H-D-A-D-S-L-R-A-I-E-I-L-A-A-L-E-R-T-Q-K-V-T-I-D-Q-A-E-L-S-R-M-V-N-L-E-G-V-Y-V-V-V-S-E-A-A-Q-N"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-K-S-G-E-P-V-N-S-H-D-V-T-D-E-Q-W-E-G-L-A-Q-V-V-P-L-R-G-R-D-A-W-P-S-A-V-G-H-R-A-M-P-E-A-E-T-E-R-R-R-R-F-V-V-L-R-I-N-V-F-A-D-A-R-E-V-A-E-T-L-M-A-G-I-P-V-L-L-D-L-T-S-A-E-G-E-V-A-K-R-V-L-D-F-S-T-G-V-V-F-G-L-A-S-G-M-H-R-V-D-R-N-V-F-L-L-T-P-A-G-T-E-V-N-G-L-M-E-S-A-A-G-V-P-G-V"} +{"text": "### FUNCTION Potential regulator of the malBH genes ### SEQUENCE -M-I-D-L-E-R-K-N-K-Y-K-C-S-I-E-Y-T-L-S-F-M-G-G-K-W-K-P-I-I-L-W-H-L-G-T-E-G-I-H-R-Y-G-E-L-K-R-K-L-D-G-I-T-H-K-M-L-A-Q-Q-L-K-E-L-A-D-D-N-L-I-I-R-K-E-Y-P-Q-V-P-P-K-V-E-Y-S-I-T-E-K-G-M-G-L-M-E-I-L-N-L-M-H-K-W-G-Q-E-N"} +{"text": "### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-E-F-T-H-L-N-E-S-G-R-A-R-M-V-D-V-G-G-K-D-D-T-N-R-E-A-T-A-R-A-C-I-K-M-N-R-E-T-I-S-M-I-R-D-G-Q-M-K-K-G-D-V-L-S-V-A-Q-V-G-G-I-M-G-A-K-R-T-S-D-I-I-P-M-C-H-N-I-F-I-S-G-V-D-I-E-F-K-L-H-E-E-E-I-E-I-S-A-V-A-K-T-R-G-K-T-G-I-E-M-E-A-L-T-A-V-S-V-A-A-L-T-I-Y-D-M-C-K-A-V-D-K-G-M-V-I-S-D-I-M-L-I-K-K-T-G-G-K-S-G-D-Y-E-R-E-S-I"} +{"text": "### FUNCTION Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'--3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism ### SEQUENCE -M-S-T-S-H-P-T-G-L-E-I-L-E-F-T-F-P-G-S-R-P-A-G-A-I-A-P-V-L-V-G-V-V-G-S-G-N-L-E-V-L-L-E-A-A-A-G-S-D-C-S-V-R-I-E-T-S-A-R-G-F-G-P-I-W-E-A-V-L-R-D-F-H-E-R-H-P-L-A-G-V-R-V-S-I-N-D-M-G-A-T-P-A-V-V-S-L-R-L-D-Q-A-A-A-E-V-A-S"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-T-V-D-H-T-R-M-S-A-P-A-V-R-V-A-K-T-M-K-T-P-S-G-D-T-I-T-V-F-D-L-R-F-T-V-P-N-K-K-A-M-P-E-K-G-I-H-T-L-E-H-L-F-A-G-F-M-R-N-H-L-N-G-E-G-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-Q-P-D-E-Q-R-V-A-N-A-W-K-A-A-M-E-D-V-L-K-V-K-D-Q-N-H-I-P-E-L-N-V-Y-Q-C-G-T-Y-E-M-H-S-L-A-E-A-Q-D-I-A-R-D-I-L-S-H-T-I-G-I-N-H-N-D-E-L-A-L-P-E-D-K-L-K-E-L-Q-I"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-T-N-R-R-V-S-R-V-A-E-L-I-K-R-E-V-S-Q-M-L-L-N-G-I-K-D-D-R-V-G-T-G-M-V-S-V-T-D-V-D-V-S-G-D-L-Q-H-A-K-I-Y-V-S-I-Y-G-T-D-E-A-K-V-E-T-M-A-G-L-K-S-A-T-G-Y-V-R-S-E-L-G-A-R-V-R-L-R-R-T-P-E-V-I-F-L-E-D-R-S-I-E-R-G-N-K-V-L-A-L-L-S-Q-L-N-H-D-R-P-P-E-N-L-L-A-V-E-D-N-T-D-E-D-D-E-S-F-S-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-F-K-P-L-H-D-R-V-L-V-R-R-V-Q-S-D-E-K-T-K-G-G-L-I-I-P-D-T-A-K-E-K-P-A-E-G-E-V-V-A-C-G-E-G-A-R-K-D-S-G-E-L-I-A-M-S-V-K-A-G-D-R-V-L-F-G-K-W-S-G-T-E-V-T-I-D-G-A-E-L-L-I-M-K-E-S-D-I-L-G-I-L-S"} +{"text": "### FUNCTION Required for growth and/or survival at acidic conditions ### SEQUENCE -M-K-K-V-L-A-L-V-V-A-A-A-M-G-L-S-S-A-A-F-A-A-E-T-A-T-P-A-K-T-A-A-P-A-K-T-T-Q-T-T-Q-H-H-K-K-Q-H-K-K-T-V-E-Q-K-A-Q-A-A-K-K-H-Q-K-K-D-G-K-K-A-P-A-K-S-T-S-K-T-T-S-Q-P-A-A"} +{"text": "### FUNCTION Required for growth and/or survival at acidic conditions ### SEQUENCE -M-K-K-V-L-A-L-V-V-A-A-A-M-G-L-S-S-A-A-F-A-A-D-A-V-S-T-T-Q-A-P-A-A-T-H-S-T-A-A-K-T-T-H-H-K-K-H-H-K-A-A-A-K-P-A-A-E-Q-K-A-Q-A-A-K-K-H-K-K-A-E-A-K-P-A-A-A-Q-K-A-Q-A-A-K-K-H-K-K-V-A-A-K-P-A-A-P-Q-K-A-Q-A-A-K-K-H-H-K-A-A-A-K-P-A-A-Q-K-A-Q-A-A-K-K-H-H-K-T-T-K-H-Q-A-A-K-P-T-A-Q-P-A-A"} +{"text": "### FUNCTION Required for growth and/or survival at acidic conditions ### SEQUENCE -M-K-K-V-L-A-L-V-V-A-A-A-M-G-L-S-S-A-A-F-A-A-E-T-T-A-T-A-A-P-A-A-S-T-A-A-P-A-K-T-V-H-H-K-K-H-H-K-A-A-K-P-A-A-E-Q-K-A-Q-A-A-K-K-H-H-K-K-A-A-K-P-A-V-E-Q-K-A-Q-A-A-K-K-H-H-K-K-A-A-K-H-E-A-A-K-P-A-A-Q-P-A-A"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-A-L-D-Y-R-K-T-F-E-I-E-I-I-N-E-F-Q-S-A-I-H-S-K-M-L-N-Y-V-L-N-N-E-L-D-K-S-D-S-T-N-L-Q-T-N-L-L-N-Q-L-S-N-M-N-Q-I-N-L-F-K-L-S-L-E-E-L-E-A-Y-H-E-Y-L-R-S-I-K-K-Y-A-D-S-I-T-R-T-T"} +{"text": "### FUNCTION Unknown, does not seem to be involved in regulation of the ttgGHI or ttgVW operons ### SEQUENCE -M-A-R-K-T-A-A-E-A-K-E-T-R-Q-R-I-I-D-A-A-L-E-V-F-V-A-Q-G-V-P-D-A-T-L-D-Q-I-A-R-K-A-G-V-T-R-G-A-V-Y-W-H-F-N-G-K-L-E-V-L-Q-A-V-L-A-S-R-Q-H-P-L-E-L-D-F-T-P-D-L-G-I-E-R-S-W-E-A-V-V-V-A-M-L-D-A-V-H-S-P-Q-S-K-Q-F-S-E-I-L-I-Y-Q-G-L-D-E-S-G-L-I-H-N-R-M-V-Q-A-S-D-R-F-L-Q-Y-I-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-Y-E-Y-L-D-R-R-Y-A-V-A-L-Y-N-I-A-S-A-E-N-K-V-E-E-Y-I-A-D-L-K-Q-I-N-D-L-I-K-N-N-E-D-L-N-Q-I-I-S-N-P-K-I-S-T-T-K-K-R-E-I-F-T-S-I-F-E-D-K-I-D-L-K-L-F-S-F-L-I-I-L-I-E-K-K-R-I-D-Q-L-T-G-I-I-L-Q-I-E-K-V-D-L-D-N-H-N-Q-V-V-A-E-V-K-T-V-V-P-L-N-N-S-E-R-T-A-L-I-D-K-L-Q-I-K-Y-N-K-S-I-I-L-R-E-V-I-D-K-S-I-I-G-G-V-Y-V-R-V-G-D-D-V-I-D-G-T-I-K-N-K-I-E-E-M-K-K-L-M-F-I-K-G"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-D-K-K-K-N-A-E-E-F-E-E-T-F-S-D-K-T-S-E-D-E-S-T-V-E-N-E-T-V-E-E-N-E-N-E-D-V-Q-A-I-S-E-V-D-D-L-K-A-Q-L-D-E-M-E-D-K-Y-L-R-A-S-A-E-L-S-N-M-N-N-R-F-R-N-E-R-Q-T-L-Q-R-Y-R-S-Q-D-L-G-K-K-L-L-P-A-I-D-N-L-E-R-A-V-A-I-E-V-E-G-E-Q-N-E-S-L-K-K-G-V-E-M-T-L-E-S-L-R-S-A-M-Q-E-E-G-I-E-E-I-S-A-Q-G-E-T-F-D-P-T-L-H-Q-A-V-Q-T-V-P-A-T-E-D-H-P-A-E-T-V-V-E-V-L-Q-K-G-Y-K-I-Y-D-R-V-L-R-A-S-M-V-V-V-A-Q"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-R-S-F-K-E-F-E-G-T-D-R-H-V-K-S-A-S-G-T-W-E-S-T-R-I-V-L-A-K-E-K-V-G-F-S-V-H-E-T-I-L-Y-A-G-T-E-T-S-M-W-Y-A-N-H-I-E-A-V-V-C-T-K-G-D-A-E-L-T-D-R-E-T-G-K-T-Y-H-I-T-P-G-T-M-Y-L-L-D-G-H-E-R-H-T-L-K-V-K-E-D-F-H-C-I-C-V-F-N-P-P-V-T-G-R-E-D-H-D-E-N-G-V-Y-P-L-L-T-E-E-V"} +{"text": "### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate with acetyl coenzyme A ### SEQUENCE -M-T-A-A-Q-A-D-L-Q-I-D-R-P-R-V-A-D-G-A-A-L-W-R-I-A-R-D-S-E-V-L-D-L-N-S-S-Y-S-Y-L-L-W-C-R-D-F-A-A-T-S-A-V-V-R-D-G-H-G-V-P-V-G-F-I-T-G-Y-V-R-P-D-S-P-D-T-L-L-V-W-Q-V-A-V-D-G-T-Y-R-G-R-G-L-A-A-T-L-V-D-G-L-A-D-R-V-A-R-E-R-G-I-T-I-L-E-T-T-I-S-P-D-N-T-A-S-Q-R-L-F-T-S-F-A-E-R-R-G-A-R-L-E-R-E-V-L-F-D-T-A-V-F-P-D-G-P-H-E-P-E-V-L-Y-R-I-G-P-L-S-A-G-G"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-A-T-H-K-K-P-D-L-S-D-P-T-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-V-F-P-I-V-I-M-G-S-F-A-C-I-V-A-L-A-V-L-D-P-A-M-T-G-E-P-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-L-Y-P-V-F-Q-I-L-R-S-L-P-N-K-L-L-G-V-L-A-M-A-S-V-P-L-G-L-I-L-V-P-F-I-E-N-V-N-K-F-Q-N-P-F-R-R-P-V-A-T-T-V-F-L-F-G-T-L-V-T-L-W-L-G-I-G-A-A-L-P-L-D-K-S-L-T-L-G-L-F"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-K-S-L-L-V-I-A-I-G-A-S-L-G-A-W-L-R-W-L-L-G-M-K-L-N-A-L-F-P-T-I-P-P-G-T-V-V-A-N-M-V-G-G-Y-I-I-G-L-A-I-A-F-L-A-A-S-P-S-L-S-P-E-W-R-L-L-I-I-T-G-F-C-G-G-L-T-T-F-S-T-F-S-A-E-T-V-A-L-I-Q-E-G-R-L-L-W-A-L-G-S-I-S-L-H-V-V-G-S-L-A-M-T-A-A-G-L-L-S-Y-Q-M-I-G-T-R"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-T-D-Q-Q-N-T-A-A-S-E-D-E-A-A-P-Q-F-S-L-Q-R-I-Y-V-R-D-L-S-F-E-A-P-K-S-P-A-I-F-R-Q-Q-W-E-P-S-V-G-L-D-L-N-T-R-Q-K-A-L-E-D-D-F-H-E-V-V-L-T-L-S-V-T-V-K-N-G-D-E-V-A-F-I-A-E-V-Q-Q-A-G-I-F-L-I-R-N-L-D-A-A-S-M-S-H-T-L-G-A-F-C-P-N-I-L-F-P-Y-A-R-E-T-L-D-S-L-V-T-R-G-S-F-P-A-L-M-L-A-P-V-N-F-D-A-L-Y-A-Q-E-L-Q-R-M-Q-Q-E-G-G-A-T-V-Q"} +{"text": "### FUNCTION Curlin is the structural subunit of the curli Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius Curli can bind to fibronectin ### SEQUENCE -M-K-L-L-K-V-A-A-I-A-A-I-V-F-S-G-S-A-L-A-G-V-V-P-Q-Y-G-G-G-G-G-N-H-G-G-G-G-N-N-S-G-P-N-S-E-L-N-I-Y-Q-Y-G-G-G-N-S-A-L-A-L-Q-A-D-A-R-N-S-D-L-T-I-T-Q-H-G-G-G-N-G-A-D-V-G-Q-G-S-D-D-S-S-I-D-L-T-Q-R-G-F-G-N-S-A-T-L-D-Q-W-N-G-K-D-S-H-M-T-V-K-Q-F-G-G-G-N-G-A-A-V-D-Q-T-A-S-N-S-T-V-N-V-T-Q-V-G-F-G-N-N-A-T-A-H-Q-Y"} +{"text": "### FUNCTION DNA-binding protein that specifically recognizes a negative element within the RPS1 promoter ### SEQUENCE -M-A-A-E-F-D-G-K-I-E-S-K-G-L-N-P-G-L-I-V-L-L-V-I-G-G-L-L-L-T-F-L-V-G-N-F-I-L-Y-T-Y-A-Q-K-N-L-P-P-R-K-K-K-P-V-S-K-K-K-M-K-K-E-K-M-K-Q-G-V-Q-V-P-G-E"} +{"text": "### FUNCTION May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule ### SEQUENCE -M-G-F-T-E-K-Q-E-G-L-V-K-E-S-W-E-V-L-K-Q-D-I-P-H-S-S-L-R-F-F-S-L-I-L-E-I-A-P-G-A-K-N-M-F-S-F-L-R-E-S-E-E-I-P-Q-N-N-P-K-L-K-A-H-A-V-K-V-F-K-M-T-C-E-S-A-I-Q-L-R-E-K-G-E-V-V-V-A-D-T-T-L-K-Y-L-G-T-V-H-V-K-S-G-V-K-D-P-H-F-E-V-V-K-E-A-L-L-R-T-I-E-E-A-I-G-E-E-K-W-N-E-E-M-K-N-A-W-G-E-A-Y-D-Q-L-A-E-A-I-K-A-E-M-K-N-H-H-D-E-T-A"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-D-H-L-M-C-E-I-E-G-N-R-L-T-S-A-A-I-I-G-Q-D-G-S-V-W-A-Q-S-A-T-F-P-Q-F-K-P-E-E-I-T-A-I-M-N-D-F-A-E-P-G-T-L-A-P-T-G-L-Y-L-G-G-T-K-Y-M-V-I-Q-G-E-A-G-A-V-I-R-G-K-K-G-P-G-G-I-T-V-K-K-T-N-Q-A-L-I-I-G-I-Y-D-E-P-M-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-I-E-Q-S-L"} +{"text": "### FUNCTION Does not possess nicotinamidase activity in vitro ### SEQUENCE -M-A-E-R-W-R-N-T-A-L-L-V-I-D-M-Q-N-D-F-I-E-E-G-A-V-T-Q-V-K-G-G-K-S-I-V-P-N-V-I-R-V-V-E-L-A-R-Q-R-G-I-L-V-I-W-V-V-R-E-H-D-R-Q-G-R-D-V-E-L-F-R-R-H-N-Y-S-S-E-K-V-G-P-V-I-K-G-T-V-G-A-E-L-V-D-G-L-M-I-N-E-E-D-D-Y-K-I-V-K-T-R-F-S-A-F-F-S-T-N-L-H-S-F-L-Q-T-S-G-V-T-K-L-V-I-A-G-V-Q-T-P-N-C-I-R-Q-T-V-F-D-A-V-A-L-D-Y-P-N-V-T-V-I-T-D-A-T-A-A-A-T-P-E-I-H-T-A-N-I-L-D-M-K-N-I-G-V-K-T-P-T-L-H-E-W-S-E-E-L-A"} +{"text": "### FUNCTION General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery Binds single-stranded DNA ### SEQUENCE -M-S-S-S-S-S-S-E-D-E-L-E-K-K-V-T-K-E-Q-K-K-K-E-T-K-S-K-K-R-Q-S-E-A-V-E-E-E-K-Q-E-V-K-K-A-K-N-E-E-E-V-S-G-R-L-K-D-S-D-G-N-E-M-F-E-I-G-N-L-R-Y-A-T-V-S-K-F-K-G-K-E-Y-V-N-I-R-E-Y-Y-I-D-R-D-S-Q-K-M-M-P-S-R-K-G-I-S-L-S-K-A-Q-W-A-N-L-K-D-L-I-P-E-I-D-K-K-F"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-D-H-L-M-C-E-T-D-G-Q-H-L-T-A-A-A-I-I-G-H-D-G-S-V-W-A-Q-S-A-N-F-P-Q-F-K-P-A-E-I-A-A-I-M-K-D-F-D-E-P-G-S-L-A-P-T-G-L-H-L-G-G-T-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-P-G-G-I-T-V-K-K-T-T-Q-A-L-I-I-G-I-Y-D-E-P-M-T-P-G-Q-C-N-M-V-V-E-R-L-G-D-Y-L-V-D-Q-G-L"} +{"text": "### FUNCTION May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule ### SEQUENCE -M-G-E-I-V-F-T-E-K-Q-E-A-L-V-K-E-S-W-E-I-L-K-Q-D-I-P-K-Y-S-L-H-F-F-S-Q-I-L-E-I-A-P-A-A-K-D-M-F-S-F-L-R-D-T-D-E-V-P-H-N-N-P-K-L-K-A-H-A-V-K-V-F-K-M-T-C-E-T-A-I-Q-L-R-E-K-G-K-V-V-V-A-D-T-T-L-Q-Y-L-G-S-V-H-F-K-S-G-V-L-D-P-H-F-E-V-V-K-E-A-L-V-R-T-L-K-E-G-L-G-E-K-Y-N-E-E-V-E-G-A-W-S-K-A-Y-D-H-L-A-L-A-I-K-A-E-M-K-Q-E-D-S-Q-K-P"} +{"text": "### FUNCTION The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways ### SEQUENCE -M-E-A-A-A-A-R-P-V-I-R-V-A-A-I-C-G-S-L-R-K-A-S-Y-N-G-G-L-L-R-A-A-A-G-V-C-E-E-S-I-P-G-L-R-V-D-H-V-D-I-S-G-L-P-L-L-N-T-D-L-E-T-A-D-G-G-F-P-P-A-V-E-A-F-R-D-K-V-R-Q-A-D-C-F-L-F-G-S-P-E-Y-N-Y-S-I-A-T-P-L-K-N-A-L-D-W-A-S-R-G-Q-N-C-W-A-D-K-P-A-A-I-V-S-A-G-G-G-F-G-G-G-R-S-Q-Y-H-L-R-Q-V-G-V-F-L-D-L-H-F-I-N-K-P-E-L-A-V-K-A-F-E-Q-P-P-K-F-D-S-D-G-N-L-I-D-A-Q-I-R-E-R-I-K-Q-V-L-L-S-L-Q-A-F-T-L-R-L-Q-K-K-D"} +{"text": "### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-E-Q-G-S-E-R-Q-D-E-R-P-P-L-P-C-A-N-G-C-G-F-F-G-S-A-D-T-R-G-L-C-S-K-C-Y-R-Q-T-V-M-S-Q-A-S-A-P-S-A-A-A-Q-S-A-E-H-D-Q-V-V-L-P-A-P-E-G-V-P-V-D-E-G-A-M-P-P-P-P-P-R-H-G-A-K-T-K-S-R-C-A-A-C-G-R-S-V-G-L-M-G-F-E-C-R-C-G-A-V-F-C-G-A-H-R-Y-S-D-R-H-D-C-G-Y-D-Y-R-G-A-G-R-D-A-I-A-R-A-N-P-V-V-R-P-D-K-V-E-K-L"} +{"text": "### FUNCTION Component of the signal peptidase complex ### SEQUENCE -M-D-W-Q-G-Q-K-L-V-E-Q-L-M-Q-I-L-L-V-I-S-G-V-V-A-V-V-V-G-Y-T-T-E-S-F-R-T-M-M-L-I-Y-A-G-G-V-V-L-T-T-L-V-T-V-P-N-W-P-F-Y-N-L-H-P-L-K-W-L-D-P-S-E-A-E-K-H-P-K-P-E-V-V-S-V-A-S-K-K-K-F-S-K-K"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-V-Y-Q-D-L-L-T-G-D-E-L-L-S-D-S-F-R-Y-K-E-I-E-N-G-M-L-W-E-V-E-G-K-W-V-V-K-G-A-V-D-V-D-I-G-A-N-P-S-A-E-G-G-G-E-D-E-G-V-D-D-A-A-V-K-V-V-D-I-V-D-T-F-R-L-Q-E-Q-P-A-F-D-K-K-Q-F-V-T-F-M-K-R-F-I-K-N-L-T-P-K-L-D-A-E-Q-Q-E-L-F-K-K-H-I-E-G-A-T-K-Y-L-L-S-K-I-K-D-F-Q-F-F-V-G-E-S-M-G-D-D-A-C-L-V-F-A-Y-Y-K-D-G-A-A-D-P-T-F-L-Y-F-A-Y-A-L-K-E-V-K-C"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-V-Y-T-D-L-L-T-G-D-E-L-L-S-D-S-F-P-Y-K-E-I-E-N-G-I-L-W-E-V-E-G-K-W-T-T-K-G-C-V-E-V-N-I-G-A-N-P-S-A-E-E-G-G-E-D-E-G-V-D-D-S-V-E-K-V-V-D-I-V-D-T-F-R-L-Q-E-Q-P-T-Y-D-K-K-G-F-I-A-Y-I-K-K-Y-I-K-L-L-T-P-K-L-T-P-E-Q-Q-E-E-F-K-K-G-I-E-G-A-T-K-F-L-L-P-K-L-K-D-F-Q-F-F-V-G-E-G-M-H-D-D-S-T-I-V-F-A-Y-Y-K-E-G-A-T-N-P-T-F-L-Y-F-A-H-G-L-K-E-V-K-C"} +{"text": "### FUNCTION The metallothioneins are involved in the cellular sequestration of toxic metal ions ### SEQUENCE -M-S-D-P-C-N-C-V-E-T-G-D-C-R-C-A-D-G-S-C-S-D-C-S-N-C-K-C-G-D-S-C-K-C-S-K-P-N-C-C-G-K-N-V-T-C-K-C-G-E-N-C-Q-C-G-V-G-C-T-G-P-D-S-C-T-C-D-S-G-C-S-C-K"} +{"text": "### FUNCTION Acts as an enhancer of the rudimentary gene Has a role in pyrimidine biosynthesis and the cell cycle ### SEQUENCE -M-S-H-T-I-L-L-V-Q-P-G-A-R-P-E-T-R-T-Y-C-D-Y-E-S-V-N-E-C-M-E-G-V-C-K-I-Y-E-E-H-L-K-R-R-N-P-N-T-P-T-I-T-Y-D-I-S-Q-L-F-D-F-I-D-T-L-I-D-I-S-C-L-V-Y-Q-K-S-T-N-T-Y-A-P-Y-N-K-D-W-I-K-E-K-I-Y-V-L-L-R-Q-A-A-F-S-P-N-A"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-Y-I-Y-N-C-I-F-T-G-K-E-V-F-S-D-A-Y-P-H-K-L-E-D-E-G-F-V-W-V-V-D-G-K-Y-E-E-L-A-D-Q-K-F-D-D-S-L-F-G-G-N-K-S-A-E-G-E-D-D-E-G-E-A-S-T-E-Y-K-P-V-V-N-T-L-L-R-A-F-R-L-E-E-P-V-T-I-T-S-L-N-D-F-K-K-A-L-K-K-Y-T-V-N-L-M-A-K-L-N-E-S-N-Q-S-R-V-A-V-L-K-S-K-L-P-K-Y-A-K-Q-W-A-E-D-F-D-K-I-R-V-Y-V-T-E-G-D-G-F-E-V-E-G-T-L-V-V-I-T-Q-D-V-P-F-G-E-E-K-P-N-D-K-C-K-M-T-V-L-A-D-S-L-I-K-E-K-F"} +{"text": "### FUNCTION Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts ### SEQUENCE -M-S-D-E-E-H-H-F-E-P-A-A-D-A-G-A-S-K-T-Y-P-Q-Q-A-G-T-I-R-K-N-G-Y-I-V-I-K-S-R-P-C-K-V-V-E-V-S-T-S-K-T-G-K-H-G-H-A-K-C-H-F-V-A-I-D-I-F-N-G-K-K-L-E-D-I-V-P-S-S-H-N-C-D-V-P-H-V-N-R-T-D-Y-Q-L-I-D-I-S-E-D-G-F-V-S-L-L-T-D-N-G-S-T-K-D-D-L-K-L-P-T-D-D-S-L-L-T-Q-I-K-D-G-F-A-D-G-K-D-L-V-V-S-V-M-S-A-M-G-E-E-Q-I-C-A-L-K-D-I-G-P-K"} +{"text": "### FUNCTION Secreted effector that suppresses host plant glucan elicitor-mediated defense responses ### SEQUENCE -V-L-T-L-E-K-P-S-K-F-A-P-I-K-L-P-K-A-D-G-S-D-I-F-P-R-V-W-S-K-V-M-G-W-G-V-T-S-Y-P-N-G-K-P-S-N-E-L-Q-S-V-D-V-R-V-W-G-D-N-A-C-E-N-K-L-G-V-D-K-S-S-L-C-A-G-G-E-A-G-K-D-S-C-V-G-D-T-G-D-P-L-I-K-E-N-G-R-G-D-A-D-D-I-L-L-G-L-S-G-W-G-T-G-C-G-D-K-D-M-P-S-V-Y-S-R-V-S-A-G-I-E-W-I-N-S-V-I-K-K"} +{"text": "### FUNCTION Mediates the homing of a group I intron in the ribosomal DNA Makes a four-base staggered cut in its ribosomal DNA target sequence ### SEQUENCE -M-A-L-T-N-A-Q-I-L-A-V-I-D-S-W-E-E-T-V-G-Q-F-P-V-I-T-H-H-V-P-L-G-G-G-L-Q-G-T-L-H-C-Y-E-I-P-L-A-A-P-Y-G-V-G-F-A-K-N-G-P-T-R-W-Q-Y-K-R-T-I-N-Q-V-V-H-R-W-G-S-H-T-V-P-F-L-L-E-P-D-N-I-N-G-K-T-C-T-A-S-H-L-C-H-N-T-R-C-H-N-P-L-H-L-C-W-E-S-L-D-D-N-K-G-R-N-W-C-P-G-P-N-G-G-C-V-H-A-V-V-C-L-R-Q-G-P-L-Y-G-P-G-A-T-V-A-G-P-Q-Q-R-G-S-H-F-V-V"} +{"text": "### FUNCTION Plays a fundamental role in microtubule organizing center structure and function Component of the infraciliary lattice ### SEQUENCE -M-A-R-R-G-Q-Q-P-P-P-Q-Q-A-P-P-A-Q-K-N-Q-T-G-K-F-N-P-A-E-F-V-K-P-G-L-T-E-E-E-V-L-E-I-K-E-A-F-D-L-F-D-T-D-G-T-Q-S-I-D-P-K-E-L-K-A-A-M-T-S-L-G-F-E-A-K-N-Q-T-I-Y-Q-M-I-S-D-L-D-T-D-G-S-G-Q-I-D-F-A-E-F-L-K-L-M-T-A-R-I-S-E-R-D-S-K-A-D-I-Q-K-V-F-N-L-F-D-S-E-R-A-G-V-I-T-L-K-D-L-R-K-V-A-K-E-L-G-E-T-M-D-D-S-E-L-Q-E-M-I-D-R-A-D-S-D-G-D-A-Q-V-T-F-E-D-F-Y-N-I-M-T-K-K-T-F-A"} +{"text": "### FUNCTION Calcium-binding protein ### SEQUENCE -M-V-M-D-T-N-S-L-R-H-I-F-S-R-V-D-A-D-K-S-G-S-I-S-A-N-E-L-Q-T-S-L-S-N-G-L-G-T-P-L-N-I-R-T-V-Q-L-M-V-A-M-F-D-R-D-M-N-G-T-I-N-F-N-E-F-L-G-L-F-K-Y-V-Q-D-W-Q-T-C-F-R-R-Y-D-R-D-N-S-G-S-I-D-L-N-E-F-S-N-A-L-I-S-F-G-Y-H-L-S-P-Q-F-V-N-L-M-M-R-R-F-D-R-N-R-G-S-I-A-F-D-D-F-I-Y-A-C-V-C-L-Q-T-L-T-R-E-F-S-R-Y-D-C-R-G-I-G-H-T-V-F-S-F-E-Q-F-L-T-S-A-F-A-V-I-I"} +{"text": "### FUNCTION Acts as a non-catalytic accessory component of a dynein complex ### SEQUENCE -M-G-E-R-K-A-V-I-K-N-A-D-M-H-E-D-M-Q-E-T-A-V-H-T-A-A-A-A-L-D-K-Y-E-I-E-K-D-V-A-A-Y-I-K-K-E-F-D-R-K-Y-N-P-N-W-H-C-I-V-G-K-H-F-G-S-Y-V-T-H-E-T-Q-H-F-I-Y-F-Y-L-Q-E-R-A-F-L-L-F-K-S-G"} +{"text": "### FUNCTION Acts as a non-catalytic accessory component of a dynein complex ### SEQUENCE -M-S-E-R-K-A-V-I-K-N-A-D-M-S-E-E-M-Q-E-D-A-I-H-I-A-A-G-A-I-D-K-H-D-L-E-K-D-I-A-A-N-I-K-K-D-F-D-R-K-Y-H-P-T-W-H-C-I-V-G-R-H-F-G-S-Y-V-T-H-E-T-H-N-F-I-Y-F-Y-L-D-D-R-A-F-L-L-F-K-S-G"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-G-D-V-E-K-Q-T-E-I-R-E-K-K-A-R-N-V-M-R-E-L-K-I-Q-K-L-C-L-N-I-C-V-G-E-F-G-D-R-L-T-R-A-A-K-V-L-E-Q-L-T-G-Q-T-P-V-F-S-K-A-R-Y-T-V-R-T-F-G-I-R-R-N-E-K-I-A-V-H-C-T-V-R-G-P-K-A-E-E-I-L-E-K-G-L-K-V-K-E-Y-E-L-Y-K-E-N-F-S-D-T-G-N-F-G-L-G-V-Q-E-H-I-D-L-G-I-K"} +{"text": "### FUNCTION May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule ### SEQUENCE -M-A-T-Y-E-G-K-V-F-T-E-E-Q-E-A-L-V-V-K-S-W-T-V-M-K-K-K-T-A-E-L-G-L-K-F-F-L-K-I-F-E-I-A-P-S-A-K-K-L-F-S-F-L-R-D-S-N-V-P-L-E-Q-N-T-K-L-K-P-H-A-M-S-V-F-V-M-T-C-E-S-A-V-Q-L-R-K-A-G-K-V-T-V-R-E-S-N-L-K-K-L-G-A-T-H-F-K-Y-G-V-V-D-E-H-F-E-V-T-K-F-A-L-L-E-T-I-K-E-A-V-P-D-M-W-S-D-E-M-K-N-A-W-G-E-A-Y-D-R-L-V-A-A-I-K-I-E-M-K-A-C-S-Q-A-A"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-A-E-V-E-V-R-V-R-Q-E-Q-V-A-E-F-R-E-T-F-A-F-F-D-K-D-G-D-G-C-I-T-L-E-E-L-D-T-V-V-R-S-L-G-Q-T-P-T-R-E-E-L-A-E-M-I-R-D-V-D-V-D-G-N-G-T-I-E-F-A-E-F-L-A-L-M-A-R-K-A-S-R-G-G-E-N-G-G-G-G-D-D-S-G-D-A-A-D-E-E-L-R-E-A-F-K-V-F-D-K-D-Q-D-G-L-I-S-A-A-E-L-R-H-V-M-I-S-L-G-E-K-L-T-D-E-E-V-E-Q-M-I-R-E-A-D-L-D-G-D-G-Q-V-N-F-D-E-F-V-R-M-M-M-L-S-D-Q"} +{"text": "### FUNCTION Component of the cuticle of tobacco hornworm ### SEQUENCE -M-K-S-F-F-V-V-A-L-L-V-A-A-A-A-A-A-P-A-N-P-D-A-D-A-V-I-V-R-Y-D-A-D-Q-G-D-P-Q-H-Y-S-Y-S-V-E-T-S-N-G-I-A-F-S-E-E-G-A-L-K-N-V-G-S-E-N-E-A-N-S-V-R-G-S-Y-A-Y-V-G-P-D-G-V-T-Y-S-V-V-Y-I-A-D-E-N-G-F-Q-P-Q-G-A-H-L-P-V-A-A"} +{"text": "### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-A-E-E-H-R-C-Q-T-P-E-S-N-R-L-C-V-N-N-C-G-F-L-G-S-S-A-T-M-N-L-C-S-N-C-Y-G-D-L-C-L-K-Q-Q-Q-Q-S-S-S-I-K-S-T-V-E-S-S-L-S-V-S-P-P-S-S-S-S-S-E-I-S-S-P-I-I-P-P-L-L-K-N-P-S-V-K-L-E-V-P-E-K-K-A-V-I-S-L-P-T-T-E-Q-N-Q-Q-Q-R-P-N-R-C-T-T-C-R-K-R-V-G-L-T-G-F-K-C-R-C-G-T-M-F-C-G-V-H-R-Y-P-E-I-H-G-C-S-Y-D-F-K-S-A-G-R-E-E-I-A-K-A-N-P-L-V-K-A-A-K-L-Q-K-I"} +{"text": "### FUNCTION Ubiquitin-like modifier protein which binds to a number of as yet unidentified target proteins ### SEQUENCE -M-A-A-A-G-G-G-G-A-G-A-A-G-G-G-K-V-S-F-K-I-I-L-T-S-D-P-K-L-P-F-K-V-F-S-V-P-E-A-A-P-F-T-A-V-L-K-F-A-A-E-E-F-K-V-P-P-Q-T-S-A-I-I-T-N-D-G-V-G-I-N-P-Q-Q-S-A-G-N-V-F-L-K-H-G-S-E-L-R-L-I-P-R-D-R-V-G-A-L-A-A-P-F"} +{"text": "### FUNCTION Ubiquitin-like modifier protein which binds to a number of as yet unidentified target proteins ### SEQUENCE -M-S-Q-Q-A-A-A-V-T-K-V-T-F-K-V-T-L-T-S-D-P-K-L-P-F-R-V-F-S-V-P-E-E-A-P-F-T-A-V-L-K-F-A-A-E-E-F-K-V-P-A-Q-T-S-A-I-I-T-N-D-G-V-G-I-N-P-Q-Q-I-A-G-N-V-F-L-K-H-G-S-E-L-R-L-I-P-R-D-R-V-G-G-I-S-R-A-R"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-A-Y-V-D-D-H-L-M-C-E-I-D-G-Q-H-L-S-S-A-A-I-L-G-H-D-S-T-V-W-A-Q-S-P-N-F-P-Q-F-K-P-E-E-I-S-A-I-L-N-D-F-E-N-P-G-S-L-A-P-T-G-L-Y-L-G-G-T-K-Y-M-V-I-Q-G-E-P-G-V-V-I-R-G-K-K-G-T-G-G-I-T-V-K-K-T-N-L-A-L-I-I-G-V-Y-D-E-P-M-T-P-G-Q-C-N-M-V-V-E-R-L-G-D-Y-L-L-E-Q-G-F"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-A-Y-V-D-D-H-L-L-C-D-I-D-G-Q-C-L-T-A-A-A-I-V-G-H-D-G-S-V-W-A-Q-S-D-A-F-P-Q-C-K-P-E-E-I-A-A-I-M-K-D-F-D-E-P-G-S-L-A-P-T-G-L-Y-L-G-G-T-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-S-G-G-V-T-I-K-K-T-N-L-A-L-I-I-G-I-Y-N-E-P-M-T-P-G-Q-C-N-M-V-V-E-R-L-G-D-Y-L-F-D-Q-G-F"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-F-T-S-L-H-T-P-I-L-H-P-R-Y-C-H-H-P-T-P-S-C-T-Q-F-S-P-L-A-L-P-P-F-H-R-T-L-S-F-L-A-P-P-P-L-L-P-A-A-P-A-L-S-A-A-S-A-A-K-P-D-K-S-G-E-Q-K-W-V-H-E-G-L-I-M-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-L-I-L-G-Y-I-S-G-K-I-R-K-N-Y-V-R-I-L-P-G-D-R-V-K-V-E-V-T-R-Y-D-S-S-K-G-R-I-V-Y-R-L-R-S-S-T-P-S"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-A-S-L-T-L-M-T-S-P-P-C-S-R-S-S-K-S-P-S-P-S-P-S-P-S-L-S-C-N-Q-Q-Q-Q-Y-K-P-L-L-H-H-Q-W-P-P-Q-I-S-L-K-K-E-K-S-N-E-S-I-V-A-K-S-P-V-I-A-A-A-T-K-G-G-S-P-S-V-Q-E-Q-K-W-I-H-E-G-V-I-T-E-S-L-P-N-G-M-F-W-V-K-L-D-N-C-E-D-L-V-L-G-Y-I-S-G-R-I-R-R-S-F-I-R-V-L-P-G-D-R-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-T-Y-R-L-R-N-N-K-D-A-T-T-T"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-W-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-L-I-L-G-Y-V-S-G-K-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-K-D"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-M-T-Y-I-V-F-I-L-S-T-I-F-V-I-S-F-V-G-F-S-S-K-P-S-P-I-Y-G-G-V-G-L-I-V-S-G-G-V-G-C-G-I-V-M-S-F-G-G-S-F-L-G-L-M-V-F-L-I-Y-L-G-G-M-L-V-V-F-G-Y-T-T-A-M-A-T-E-Q-Y-P-E-V-W-V-S-N-K-V-V-M-G-A-F-I-S-G-L-I-V-E-V-V-F-V-L-C-V-L-N-S-E-E-L-K-G-L-F-E-L-N-G-M-G-D-W-V-I-Y-S-V-E-D-S-G-V-F-S-K-E-V-M-G-V-A-A-L-Y-S-Y-G-V-W-L-V-I-V-T-G-W-S-L-L-I-G-V-I-V-V-L-E-V-T-R-G-G"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-N-L-S-L-L-L-F-L-I-G-I-L-G-F-I-L-N-R-K-N-I-I-L-M-I-I-A-I-E-I-M-L-L-A-I-T-L-L-V-L-M-S-S-V-S-F-D-D-I-A-G-Q-T-F-S-I-Y-I-I-S-I-A-G-A-E-S-V-I-G-L-S-I-L-V-A-Y-Y-R-L-R-G-T-I-S-L-R-T"} +{"text": "### FUNCTION Seems to promote the survival of visceral and proprioceptive sensory neurons ### SEQUENCE -M-S-I-L-F-Y-V-M-F-L-A-Y-L-R-G-V-Q-G-N-S-M-D-Q-R-S-L-P-E-D-S-L-N-S-L-I-I-K-L-I-Q-A-D-I-L-K-N-K-L-S-K-Q-M-V-D-V-K-E-N-Y-Q-S-T-L-P-K-A-E-D-S-A-R-E-S-A-K-S-E-F-Q-P-V-M-V-M-G-P-E-L-L-W-Y-Q-R-R-Y-N-S-S-R-F-L-L-S-D-S-I-P-L-E-S-P-P-L-F-L-I-E-V-H-L-A-N-P-M-V-N-S-R-S-P-R-R-K-R-Y-A-E-H-K-S-H-R-G-E-Y-S-V-C-D-S-E-S-L-W"} +{"text": "### FUNCTION Sperm surface zona pellucida binding protein Helps to bind spermatozoa to the zona pellucida with high affinity Might function in binding zona pellucida and carbohydrates ### SEQUENCE -M-S-I-P-F-S-N-T-H-Y-R-I-P-Q-G-F-G-N-L-L-E-G-L-T-R-E-I-L-R-E-Q-P-D-N-I-P-A-F-A-A-A-Y-F-E-S-L-L-E-K-R-E-K-T-N-F-D-P-A-E-W-G-S-K-V-E-D-R-F-Y-N-N-H-A-F-E-E-Q-E-P-P-E-K-S-D-P-K-Q-E-E-S-Q-V-S-G-K-E-E-E-T-S-V-T-I-L-D-S-S-E-E-D-K-E-K-E-E-V-A-A-V-K-I-Q-A-A-F-R-G-H-V-A-R-E-E-V-K-K-M-K-T-D-S-L-Q-N-E-E-K-E-E-N-S-E-D-T-G-F-T-S-R-T-H-E-K"} +{"text": "### FUNCTION May play an important role in spermatogenesis and/or testis development ### SEQUENCE -M-A-A-V-V-L-G-G-D-I-M-G-P-E-R-I-F-P-N-Q-T-E-E-L-G-P-H-Q-G-P-T-E-G-T-G-D-W-S-S-E-E-P-E-E-E-Q-E-E-T-G-T-G-P-A-G-Y-S-Y-Q-P-L-N-Q-D-P-E-Q-E-E-V-E-L-A-P-V-G-D-G-E-D-V-V-A-D-I-Q-D-R-I-Q-A-L-G-L-H-L-P-D-P-P-L-E-S-E-D-E-D-E-E-G-A-T-A-L-S-N-H-S-S-I-P-M-D-P-E-H-V-E-L-V-K-R-T-M-A-G-V-S-L-P-A-P-G-V-P-A-W-A-R-E-I-S-D-A-Q-W-E-D-V-V-Q-K-A-L-Q-A-R-Q-A-T-P-A-W-K"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-M-T-Y-I-V-T-I-L-S-T-I-F-V-V-S-F-V-G-F-S-S-K-P-S-P-I-Y-G-G-V-G-L-I-V-S-G-G-V-G-C-G-I-V-L-N-Y-G-G-S-F-L-G-L-M-V-F-L-I-Y-L-G-G-M-L-V-V-F-G-Y-T-T-A-M-A-M-E-E-Y-P-E-V-W-V-S-N-N-T-V-L-L-T-F-L-L-G-L-V-G-E-V-V-L-M-I-Y-L-L-L-G-E-E-E-V-K-F-E-V-V-L-N-F-N-S-E-G-D-W-V-I-Y-D-T-G-D-S-G-M-F-S-E-E-A-M-G-V-A-A-L-Y-S-Y-G-Y-W-L-V-I-V-S-G-W-S-L-V-T-C-I-I-V-V-M-E-I-T-R-G-N"} +{"text": "### FUNCTION Protein S12 is involved in the translation initiation step ### SEQUENCE -M-P-T-K-N-Q-L-I-R-H-G-R-E-E-K-R-R-T-D-R-T-R-A-L-D-Q-C-P-Q-K-Q-G-V-C-P-R-V-S-T-R-T-P-K-K-P-N-S-A-P-R-K-I-A-K-V-R-L-S-N-R-H-D-I-F-A-H-I-P-G-E-G-H-N-S-Q-E-H-S-M-V-L-I-R-G-G-R-V-K-D-S-P-G-V-K-F-H-C-I-R-G-V-K-D-L-L-G-I-P-D-R-R-R-G-R-S-K-Y-G-A-E-K-P-K-S-I"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-N-L-I-L-M-M-I-L-I-S-S-L-I-S-T-I-L-A-I-V-A-F-W-L-P-Q-M-N-P-D-M-E-K-L-S-P-Y-E-C-G-F-D-P-L-G-S-A-R-L-P-F-S-M-R-F-F-L-V-A-I-L-F-L-L-F-D-L-E-I-A-L-L-L-P-L-P-W-S-T-H-L-D-P-T-L-M-L-M-W-A-F-T-I-I-I-L-L-T-I-G-L-I-Y-E-W-L-Q-G-G-L-E-W-A-E"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-V-L-M-V-V-F-S-V-M-F-L-I-S-L-I-A-V-A-S-N-P-S-P-Y-F-A-A-F-G-L-M-V-G-A-G-V-G-C-G-M-L-M-Q-C-G-M-T-F-L-S-M-I-L-F-L-I-Y-L-G-G-M-L-V-V-F-A-Y-S-P-A-L-A-A-E-P-Y-P-N-A-W-G-S-W-E-V-F-S-Y-V-L-V-Y-M-F-L-V-I-V-A-W-V-A-F-V-G-D-M-E-L-F-D-D-V-E-E-Y-F-G-A-M-R-R-Y-V-G-V-A-E-V-Y-N-A-G-G-Y-M-L-F-I-A-G-W-V-L-L-M-A-L-L-V-V-L-E-L-T-R-G-Y-S-R-G-C-L-R-A-V"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-R-Q-K-W-I-H-E-G-L-I-T-E-S-P-S-N-G-M-F-R-V-R-L-D-N-X-D-L-I-P-S-Y-V-S-G-K-I-R-R-S-L-I-R-I-L-P-G-D-K-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-K-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-E-K-W-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-L-V-L-G-Y-V-S-G-K-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-K-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-W-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-L-I-L-G-Y-V-S-G-K-I-R-R-S-F-M-R-I-L-P-G-D-R-V-K-V-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-K-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-W-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-M-I-L-G-Y-V-S-G-K-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-K-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-W-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-R-I-R-L-D-N-E-D-M-I-L-G-Y-V-S-G-K-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-N-S-K-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-W-I-N-E-G-L-I-T-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-L-S-L-G-Y-V-S-G-K-I-R-R-S-F-I-R-V-L-P-G-D-R-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-K-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-W-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-F-I-L-G-Y-I-S-G-R-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-I-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-N-Y"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-W-V-H-E-G-L-I-T-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-L-I-L-G-Y-I-S-G-R-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-N-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-L-I-H-E-G-L-I-I-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-L-I-L-G-Y-V-S-G-R-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-N-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-W-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-R-V-R-L-D-N-V-D-N-E-D-L-I-L-G-Y-V-S-G-R-I-R-R-S-F-I-R-I-L-P-G-X-R-V-K-I-E-V-S-R-X-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-N-B"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-L-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-W-V-R-L-D-N-E-D-L-V-L-G-Y-V-S-G-R-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-N-D"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-L-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-Q-V-R-L-D-N-G-D-L-V-L-G-Y-V-S-G-R-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-V-S-R-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-N-D"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-T-S-F-K-L-V-K-Y-I-P-R-I-K-K-K-K-S-G-L-R-K-L-A-R-K-V-P-T-D-R-L-L-K-F-E-R-V-F-K-A-Q-K-R-I-P-M-S-V-F-K-A-Q-R-V-L-D-E-I-R-W-R-Y-Y-E-E-T-V-M-I-L-N-L-M-P-Y-R-A-S-Y-P-I-L-K-L-V-Y-S-A-A-A-N-A-T-H-Y-R-D-F-D-K-A-N-L-F-I-T-K-A-E-V-S-R-S-T-I-M-K-K-F-R-P-R-A-R-G-R-S-F-P-I-K-K-S-M-C-H-I-T-I-V-L-N-I-V-K-K-S"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-P-Q-T-L-L-N-V-A-D-N-S-G-A-R-K-L-M-C-I-R-V-I-G-A-A-G-N-Q-R-Y-A-R-I-G-D-V-I-V-A-V-I-K-D-A-L-P-Q-M-P-L-E-R-S-E-V-I-R-A-V-I-V-R-T-C-K-E-F-K-C-E-D-G-I-I-I-R-Y-D-D-N-A-A-V-I-I-D-Q-K-G-N-P-K-G-T-R-V-F-G-A-I-A-E-E-L-R-G-L-N-F-T-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-K-D-T-I-A-D-L-L-T-S-I-R-N-A-D-M-N-K-K-G-T-V-R-V-V-S-T-N-I-T-E-N-I-V-K-I-L-L-R-E-G-F-I-E-S-V-R-K-H-Q-E-R-N-R-Y-F-L-V-S-T-L-R-H-Q-K-R-K-T-R-K-G-I-Y-R-T-R-T-F-L-K-R-I-S-R-P-G-L-R-I-Y-T-N-Y-Q-G-I-P-K-V-L-G-G-M-G-I-A-I-L-S-T-S-R-G-I-M-T-D-R-E-A-R-L-N-R-I-G-G-E-V-L-C-Y-I-W"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-V-P-R-G-Y-I-A-R-R-R-R-T-K-M-R-S-F-A-S-N-F-R-G-A-H-L-R-L-N-R-M-I-T-Q-Q-V-K-R-A-F-V-S-S-H-R-D-R-G-R-Q-K-R-D-F-R-R-L-W-I-T-R-I-N-A-A-T-R-V-Y-K-V-F-D-S-Y-S-K-L-I-H-N-L-Y-K-K-K-L-I-L-N-R-K-M-L-A-Q-V-A-V-S-N-P-N-N-L-Y-T-I-S-N-K-I-K-I-I-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-D-T-T-G-R-I-P-L-C-L-I-G-T-V-A-G-I-A-V-I-G-L-V-G-V-F-F-Y-G-S-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-K-K-S-L-I-Q-R-E-K-K-R-Q-K-L-E-Q-K-Y-H-L-I-R-Q-S-L-K-K-K-I-R-S-K-V-S-P-L-S-L-S-E-K-T-K-M-R-E-K-L-Q-S-L-P-R-N-S-A-P-T-R-L-H-R-R-C-F-L-T-G-R-P-R-A-N-Y-R-H-F-G-L-S-G-H-V-L-R-E-M-V-Y-E-C-L-L-P-G-A-T-R-S-S-W"} +{"text": "### FUNCTION Has an antimicrobial activity ### SEQUENCE -M-W-H-L-K-L-F-A-V-L-V-I-C-L-L-L-A-V-Q-V-H-G-S-P-I-P-E-L-S-S-A-K-R-R-P-R-R-M-T-P-F-W-R-A-V-S-L-R-P-I-G-A-S-C-R-D-D-S-E-C-L-T-R-L-C-R-K-R-R-C-S-L-S-V-A-Q-E"} +{"text": "### FUNCTION May play a role in neurogenesis May play a role in bone differentiation and matrix mineralization ### SEQUENCE -M-A-L-H-I-H-E-A-C-I-L-L-L-V-I-P-G-L-V-T-S-A-A-I-S-H-E-D-Y-P-A-D-E-G-D-Q-I-S-S-N-D-N-L-I-F-D-D-Y-R-G-K-G-C-V-D-D-S-G-F-V-Y-K-L-G-E-R-F-F-P-G-H-S-N-C-P-C-V-C-A-L-D-G-P-V-C-D-Q-P-E-C-P-K-I-H-P-K-C-T-K-V-E-H-N-G-C-C-P-E-C-K-E-V-K-N-F-C-E-Y-H-G-K-N-Y-K-I-L-E-E-F-K-V-C-V-T-L-H-T-Y"} +{"text": "### FUNCTION Displays low GTPase activity and exists predominantly in the GTP-bound form ### SEQUENCE -M-P-E-Q-S-N-D-Y-R-V-A-V-F-G-A-G-G-V-G-K-S-S-L-V-L-R-F-V-K-G-T-F-R-E-S-Y-I-P-T-V-E-D-T-Y-R-Q-V-I-S-C-D-K-S-I-C-T-L-Q-I-T-D-T-T-G-S-H-Q-F-P-A-M-Q-R-L-S-I-S-K-G-H-A-F-I-L-V-Y-S-I-T-S-R-Q-S-L-E-E-L-K-P-I-Y-E-Q-I-C-E-I-K-G-D-M-E-S-I-P-I-M-L-V-G-N-K-C-D-E-S-P-S-R-E-V-Q-S-S-E-A-E-A-L-A-R-T-W-K-C-A-F-M-E-T-S-A-K-L-N-H-N-V-K-E-L-F-Q-E-L-L-N-L-E-K-R-R-T-V-S-L-Q-I-D-G-K-K-S-K-Q-Q-K-R-K-E-K-L-K-G-K-C-V-I-M"} +{"text": "### FUNCTION Plays a role as a glutathione ### SEQUENCE -M-G-V-A-V-R-V-V-Y-C-G-A-U-G-Y-K-S-K-Y-L-Q-L-K-K-K-L-E-D-E-F-P-G-R-L-D-I-C-G-E-G-T-P-Q-V-T-G-F-F-E-V-L-V-A-G-K-L-V-H-S-K-K-G-G-D-G-Y-V-D-T-E-S-K-F-L-K-L-V-A-A-I-K-A-A-L-A-Q-G"} +{"text": "### FUNCTION Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5 This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells ### SEQUENCE -M-Y-K-I-Q-L-L-S-C-I-A-L-T-L-A-L-V-A-N-G-A-P-T-S-S-S-T-G-N-T-M-K-E-V-K-S-L-L-L-D-L-Q-L-L-L-E-K-V-K-N-P-E-N-L-K-L-S-R-M-H-T-F-N-F-Y-V-P-K-V-N-A-T-E-L-K-H-L-K-C-L-L-E-E-L-K-L-L-E-E-V-L-N-L-A-P-S-K-N-L-N-P-R-E-I-K-D-S-M-D-N-I-K-R-I-V-L-E-L-Q-G-S-E-T-G-F-T-C-E-Y-D-D-A-T-V-K-A-V-E-F-L-N-K-W-I-T-F-C-Q-S-I-Y-S-T-M-T"} +{"text": "### FUNCTION Involved in signal transduction through the Wnt pathway Promotes beta-catenin's transcriptional activity ### SEQUENCE -P-M-G-M-T-Q-P-L-S-H-S-N-Q-M-P-S-P-N-A-M-G-P-N-I-P-P-H-G-V-P-M-G-P-G-L-M-S-H-N-P-I-M-G-H-G-S-Q-E-P-P-M-V-P-Q-G-R-M-G-F-P-Q-G-F-P-P-V-Q-S-P-P-Q-Q-V-P-F-P-H-N-G-P-S-G-G-Q-G-N-F-P-G-G-M-G-F-P-G-E-G-P-L-G-R-P-S-N-L-P-Q-S-S-A-D-A-A-L-C-K-P-G-G-P-G-G-P-D-S-F-A-V-L-G"} +{"text": "### FUNCTION May play a role in cell differentiation in the intestinal epithelium ### SEQUENCE -M-A-D-S-E-R-L-S-A-P-G-C-W-A-A-C-T-T-F-S-R-T-R-K-G-I-L-L-L-A-E-I-I-L-C-L-V-I-L-I-C-F-S-A-G-T-S-G-Y-S-S-L-S-V-V-E-M-V-L-A-I-V-F-F-V-I-Y-M-C-D-L-H-T-R-A-P-F-I-N-W-P-W-S-D-F-F-R-T-L-I-A-A-I-L-Y-L-I-T-S-I-F-V-L-V-E-R-G-N-H-S-K-I-A-A-G-V-L-G-L-L-A-T-C-L-F-G-Y-D-A-Y-F-T-F-P-L-R-Q-Q-R-H-T-A-A-P-T-D-P-T-D-G-P-V"} +{"text": "### FUNCTION Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca complex are a number of protein kinases and phosphatases ### SEQUENCE -M-T-D-A-L-S-E-E-Q-I-A-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-T-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-Q-D-M-I-N-E-V-D-A-D-G-N-G-T-I-D-F-P-E-F-L-T-M-M-A-R-K-M-K-E-T-D-S-E-E-E-I-R-E-A-F-R-V-F-D-K-D-G-N-G-F-I-S-A-A-E-L-R-H-V-M-T-N-L-G-E-K-L-T-D-E-E-V-D-E-M-I-R-E-A-D-I-D-G-D-G-Q-V-N-Y-E-E-F-V-A-M-M-T-S-K"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-H-S-S-G-Y-T-R-P-L-P-K-P-S-R-P-I-F-I-R-P-I-G-C-D-V-C-Y-G-I-P-S-S-T-A-R-L-C-C-F-R-Y-G-D-C-C-H-R-G"} +{"text": "### FUNCTION Antibacterial protein ### SEQUENCE -M-T-Y-A-I-L-I-I-V-S-L-L-L-I-S-D-R-I-S-N-V-V-D-K-Y-C-S-E-N-P-L-D-C-N-E-H-C-L-K-T-K-N-Q-I-G-I-C-H-G-A-N-G-N-E-K-C-S-C-M-E-S"} +{"text": "### FUNCTION Inhibits potassium channels ### SEQUENCE -M-N-R-L-T-T-I-I-L-M-L-I-V-I-N-V-I-M-D-D-I-S-E-S-K-V-A-A-G-I-V-C-K-V-C-K-I-I-C-G-M-Q-G-K-K-V-N-I-C-K-A-P-I-K-C-K-C-K-K-G"} +{"text": "### FUNCTION Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them ### SEQUENCE -M-I-N-H-N-I-I-S-F-K-K-F-E-A-I-F-E-Q-R-P-G-G-L-E-L-N-M-P-I-E-I-G-S-N-N-V-D-L-T-S-K-P-F-N-I-K-G-G-S-H-Y-K-V-K-I-G-Y-M-A-S-E-P-I-T-D-L-I-C-Q-I-H-T-F-R-K-S-T-P-Y-G-R-D-T-Q-K-V-G-D-I-C-A-N-T-N-D-L-E-F-D-F-P-K-F-G-W-E-Q-A-S-T-Q-S-S-S-M-G-D-Y-T-I-K-M-Y-F-K-G-N-G-N-Q-D-L-A-T-F-F-Y-S-F-N-V-A-P-D-W-E-N-A-L-P-I-N"} +{"text": "### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-A-S-Y-W-A-V-C-V-V-L-V-A-G-S-H-L-V-A-G-T-A-E-V-M-S-H-V-T-A-H-F-G-K-A-L-E-Q-C-R-E-E-S-G-L-S-T-A-V-L-E-E-F-Q-H-F-W-R-D-D-F-E-V-V-H-R-E-L-G-C-A-I-L-C-M-S-N-K-F-S-L-M-Q-D-D-A-R-M-H-H-E-N-M-H-D-Y-V-K-S-F-P-Q-G-E-V-L-S-A-K-M-V-E-L-I-H-N-C-E-K-P-Y-D-D-I-K-D-D-C-E-R-V-V-K-V-A-A-C-F-K-V-D-A-K-K-A-G-I-A-P-E-V-A-M-I-E-A-V-M-E-K-Y"} +{"text": "### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-A-T-V-S-K-W-R-M-L-V-L-T-L-C-L-T-G-V-W-Q-V-E-S-S-A-D-V-M-K-K-L-T-T-G-F-A-T-A-L-E-K-C-R-D-E-L-N-L-P-D-A-V-M-Q-D-F-F-N-F-W-R-E-D-Y-E-L-V-N-R-D-M-G-C-A-I-M-C-M-A-T-K-F-D-L-V-T-E-E-Q-K-L-H-H-G-N-A-H-E-F-A-K-S-H-G-A-D-D-S-M-A-K-Q-L-V-T-M-L-H-E-C-E-T-Q-T-A-S-I-S-D-D-C-G-R-T-L-E-I-A-K-C-F-R-T-K-I-H-G-L-K-W-A-P-S-M-E-T-I-L-E-E-V-M-T-E-V"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-I-V-Y-K-D-M-I-T-E-D-E-M-F-T-D-S-H-C-P-R-V-V-A-D-F-F-Y-E-V-D-S-R-F-T-T-V-S-S-N-V-D-G-R-L-I-G-A-N-P-S-G-E-G-G-E-D-E-N-V-D-D-T-S-K-R-V-I-D-L-V-H-A-N-G-F-I-S-V-P-F-D-Q-K-S-Y-K-A-H-L-N-L-Y-L-K-T-I-I-E-R-L-Q-K-T-D-P-D-K-V-P-L-L-K-S-Q-V-N-K-Y-M-K-N-V-L-D-N-F-D-Q-Y-E-F-Y-M-G-P-P-S-N-P-D-A-M-I-V-L-M-N-F-R-E-D-G-M-T-P-Y-F-V-F-F-K-D-G-L-T"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-S-E-F-S-P-I-F-I-Y-L-V-M-S-L-L-V-S-L-I-L-L-G-L-P-F-L-F-A-S-N-S-S-T-Y-P-E-K-L-S-A-Y-E-C-G-F-D-P-F-G-D-A-R-S-R-F-D-I-R-F-Y-L-V-S-I-L-F-I-I-F-D-L-E-V-T-F-F-F-P-W-A-V-S-L-N-K-I-D-L-F-G-F-W-S-M-M-A-F-L-L-I-L-T-I-G-F-L-Y-E-W-K-R-G-A-L-D-W-E"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-Q-G-Y-K-G-P-Y-T-R-P-I-L-R-P-Y-V-R-P-V-V-S-Y-N-V-C-T-L-S-C-R-G-I-T-T-T-Q-A-R-S-C-C-T-R-L-G-R-C-C-H-V-A-K-G-Y-S-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-G-A-Q-R-G-G-F-T-G-P-I-P-R-P-P-P-H-G-R-P-P-L-G-P-I-C-N-A-C-Y-R-L-S-F-S-D-V-R-I-C-C-N-F-L-G-K-C-C-H-L-V-K-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-Q-G-Y-K-G-P-Y-T-R-P-I-L-R-P-Y-V-R-P-V-V-S-Y-N-A-C-T-L-S-C-R-G-I-T-T-T-Q-A-R-S-C-S-T-R-L-G-R-C-C-H-V-A-K-G-Y-S-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-Q-G-C-K-G-P-Y-T-R-P-I-L-R-P-Y-V-R-P-V-V-S-Y-N-A-C-T-L-S-C-R-G-I-T-T-T-Q-A-R-S-C-C-T-R-L-G-R-C-C-H-V-A-K-G-Y-S-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-Q-G-Y-K-G-P-Y-T-R-P-I-L-R-P-Y-V-R-P-V-V-S-Y-N-A-C-T-L-S-C-R-G-I-T-T-T-Q-A-R-S-C-C-T-R-L-G-R-C-C-H-V-A-K-G-Y-S-G"} +{"text": "### FUNCTION Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA ### SEQUENCE -M-S-L-V-I-P-D-K-F-Q-H-I-L-R-I-M-N-T-N-I-D-G-K-R-K-V-M-F-A-M-T-A-I-K-G-V-G-R-R-Y-S-N-I-V-L-K-K-A-D-I-D-L-D-K-R-A-G-E-C-T-E-E-E-V-E-K-I-V-T-I-M-S-N-P-R-Q-Y-K-I-P-D-W-F-L-N-R-Q-K-D-I-V-D-G-K-Y-S-Q-L-T-S-S-N-L-D-S-K-L-R-E-D-L-E-R-L-K-K-I-R-A-H-R-G-M-R-H-Y-W-G-L-R-V-R-G-Q-H-T-K-T-T-G-R-R-G-R-T-V-G-V-S-K-K-K"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-S-T-K-I-I-K-A-S-A-A-E-P-D-V-F-E-T-S-I-S-Q-A-L-V-E-L-E-T-N-S-D-L-K-A-Q-L-R-E-L-Y-I-T-K-A-K-E-I-E-L-H-N-K-K-S-I-I-I-Y-V-P-M-P-K-L-K-A-F-Q-K-I-Q-I-R-L-V-R-E-L-E-K-K-F-S-G-K-H-V-V-F-I-G-D-R-K-I-L-P-K-P-S-H-K-T-R-V-A-N-K-Q-K-R-P-R-S-R-T-L-T-S-V-Y-D-A-I-L-E-D-L-V-F-P-A-E-I-V-G-K-R-I-R-I-K-L-D-G-S-Q-L-I-K-V-H-L-D-K-N-Q-Q-T-T-I-E-H-K-V-D-T-F-Q-S-V-Y-K-K-L-T-G-R-E-V-T-F-E-F-P-E-P-Y-L"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-K-G-T-S-S-F-G-K-R-R-N-K-T-H-T-L-C-R-R-C-G-R-S-S-Y-H-I-Q-K-S-K-C-A-Q-C-G-Y-P-A-A-K-L-R-S-Y-H-W-S-V-K-A-K-R-R-K-T-T-G-T-G-R-M-R-H-L-K-I-V-R-R-R-F-R-N-G-F-K-E-G-K-P-T-P-K-K-A-V-A-S-S"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-A-R-V-P-P-P-A-L-K-K-D-K-K-E-K-K-P-P-K-D-N-S-K-N-V-M-R-N-L-H-I-R-K-L-C-L-N-I-C-V-G-E-S-G-D-R-L-T-R-A-A-K-V-L-E-Q-L-T-G-Q-Q-P-V-F-S-K-A-R-Y-T-V-R-S-F-G-I-R-R-N-E-K-I-A-V-H-C-T-V-R-G-A-K-A-E-E-I-L-E-R-G-L-K-V-R-E-Y-E-L-R-R-D-N-F-S-A-T-G-N-F-G-F-G-I-Q-E-H-I-D-L-G-I-K-Y-D-P-S-I-G-I-Y-G-L-D-F-Y-V-V-L-G-P-T-R-I-Q-C-T-T-Q-K-T-Q-D-W-Q-G-W-I-P-P-I-V-L-T-K-E-D-A-M-K-W-F-Q-Q-K-Y-D-G-I-I-L-N-S-K-K"} +{"text": "### FUNCTION Necessary for protein translocation in the endoplasmic reticulum and multi-pass membrane protein biogenesis ### SEQUENCE -M-D-Q-L-V-Q-F-V-E-P-A-R-Q-F-A-K-D-S-Y-R-L-V-K-R-C-T-K-P-D-R-K-E-F-Q-K-I-A-M-A-T-A-I-G-F-A-I-M-G-F-I-G-F-F-V-K-L-I-H-I-P-I-N-N-I-I-V-G-S"} +{"text": "### FUNCTION May have a role in the cell cycle ### SEQUENCE -M-A-N-H-N-S-S-R-H-T-I-I-L-L-Q-N-S-P-S-R-A-T-R-T-F-M-D-Y-D-S-I-G-Q-A-M-D-G-I-C-G-L-Y-E-R-K-L-K-E-I-N-P-S-L-R-N-I-S-Y-D-I-A-D-L-Y-N-F-I-D-G-L-A-D-L-S-A-L-V-Y-D-H-S-I-S-A-Y-L-P-Y-D-R-Q-W-I-K-Q-K-A-F-H-H-L-K-R-I-A-N-G-G-R"} +{"text": "### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -E-A-S-G-E-T-F-V-A-E-N-D-A-C-K-C-G-S-D-C-K-C-N-P-C-T-C-K"} +{"text": "### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-S-D-T-C-G-N-C-D-C-A-D-K-T-Q-C-V-K-K-G-S-S-Y-T-A-D-I-I-E-T-E-K-S-I-M-T-V-V-M-D-A-P-A-A-E-N-D-G-K-C-K-C-G-P-S-C-S-C-T-N-C-T-C-G-H"} +{"text": "### FUNCTION Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria ### SEQUENCE -M-N-F-A-K-V-F-V-L-V-A-M-A-V-L-L-L-V-G-Q-S-E-A-G-G-L-K-K-L-G-K-K-L-E-G-A-G-K-R-V-F-N-A-A-E-K-A-L-P-V-V-A-G-A-K-A-L-G-K"} +{"text": "### FUNCTION Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria ### SEQUENCE -M-N-F-N-K-L-F-A-I-V-L-L-A-A-L-V-L-L-G-Q-T-E-A-G-G-L-K-K-F-G-K-K-L-E-G-V-G-K-R-V-F-K-A-S-E-K-A-L-P-V-A-V-G-I-K-A-L-G-K"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-Y-S-S-G-Y-T-R-P-L-P-K-P-S-R-P-I-F-I-R-P-I-G-C-D-V-C-Y-G-I-P-S-S-T-A-R-L-C-C-F-R-Y-G-D-C-C-H-R-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-E-A-Y-R-G-G-Y-T-G-P-I-P-R-P-P-P-I-G-R-P-P-L-R-P-V-C-N-A-C-Y-R-L-S-V-S-D-A-R-N-C-C-I-K-F-G-S-C-C-H-L-V-K-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-Q-V-Y-K-G-G-Y-T-R-P-I-P-R-P-P-P-F-V-R-P-L-P-G-G-P-I-G-P-Y-N-G-R-P-V-S-C-R-G-I-S-F-S-Q-A-R-S-C-C-S-R-L-G-R-C-C-H-V-G-K-G-Y-S-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-Q-V-Y-K-G-G-Y-T-R-P-I-P-R-P-P-P-F-V-R-P-L-P-G-G-P-I-G-P-Y-N-G-C-P-I-S-C-R-G-I-S-F-S-Q-A-R-S-Y-C-S-R-L-G-R-C-C-H-V-G-K-G-Y-S-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-Q-V-Y-K-G-G-Y-T-R-P-I-P-R-P-P-P-F-V-R-P-L-P-G-G-P-I-S-P-Y-N-G-C-P-V-S-C-R-G-I-S-F-S-Q-A-R-S-C-C-S-R-L-G-R-C-C-H-V-G-K-G-Y-S-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-A-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-Q-V-Y-K-G-G-Y-T-R-P-I-P-R-P-P-P-F-V-R-P-L-P-G-G-P-I-G-P-Y-N-G-C-P-I-S-C-R-G-I-S-F-S-Q-A-R-S-C-C-S-R-L-G-R-C-C-H-V-G-K-G-Y-S-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-P-F-A-L-V-C-H-G-Q-V-Y-K-G-G-Y-T-R-P-I-P-R-P-P-P-F-V-R-P-L-P-G-G-P-I-G-P-Y-N-G-C-P-V-S-C-R-G-I-S-F-S-Q-A-R-S-C-C-S-R-L-G-R-C-C-H-V-G-K-G-Y-S-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-Q-V-Y-K-G-G-Y-T-R-P-I-P-R-P-P-P-F-V-R-P-L-P-G-G-P-I-G-P-Y-N-G-C-P-I-S-C-R-G-I-S-F-S-Q-A-R-S-C-C-S-R-L-G-R-C-C-H-V-G-K-G-Y-S-G"} +{"text": "### FUNCTION Antibacterial and antifungal activity Presents chitin-binding activity ### SEQUENCE -M-R-L-V-V-C-L-V-F-L-A-S-F-A-L-V-C-Q-G-Q-V-Y-K-G-G-Y-T-R-P-V-P-R-P-P-F-V-R-P-L-P-G-G-P-I-G-P-Y-N-G-C-P-V-S-C-R-G-I-S-F-S-Q-A-R-S-C-C-S-R-L-G-R-C-C-H-V-G-K-G-Y-S-G"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide The H form is known to activate a number of cytosolic enzymes ### SEQUENCE -M-A-E-E-A-Q-V-I-A-C-H-T-V-Q-E-W-N-E-K-F-Q-K-A-K-D-S-G-K-L-I-V-I-D-F-T-A-S-W-C-G-P-C-R-V-I-T-P-Y-V-S-E-L-A-K-K-F-P-H-V-A-F-F-K-V-D-V-D-D-L-K-D-V-A-E-E-Y-K-V-E-A-M-P-S-F-V-I-L-K-E-G-Q-E-V-E-R-I-V-G-A-R-K-D-E-L-L-H-K-I-A-V-H-A-P-I-T-A"} +{"text": "### FUNCTION A1b binds to basic 7S globulin and stimulates its phosphorylation activity ### SEQUENCE -I-P-P-S-R-S-S-D-C-R-C-V-P-I-T-L-I-V-G-F-C-I-H-P-T-G-L-S-S-V-A-K-M-I-D-E-H-P-N-L-C-Q-S-D-D-E-C-M-K-K-G-S-G-N-F-C-A-R-Y-P-N-N-Y-I-D-Y-G-W-C-F-G-S-D-S-E-A-L-K-G-F-L"} +{"text": "### FUNCTION Seems to function only as a co-chaperone, along with cpn60, and in certain cases is essential for the discharge of biologically active proteins from cpn60 ### SEQUENCE -M-M-K-R-L-I-P-T-F-N-R-I-L-V-Q-G-V-I-Q-P-A-K-T-E-S-G-I-L-L-P-E-K-A-S-K-L-N-S-G-K-V-I-A-V-G-P-G-S-R-D-K-D-G-K-L-I-P-V-S-V-K-E-G-D-T-V-L-L-P-E-Y-G-G-T-Q-V-K-L-G-E-K-E-Y-H-L-F-R-D-E-D-V-L-G-T-L-H-E-D"} +{"text": "### FUNCTION RuBisCO catalyzes two reactions the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate Both reactions occur simultaneously and in competition at the same active site Although the small subunit is not catalytic it is essential for maximal activity ### SEQUENCE -M-A-C-S-M-I-S-S-A-T-V-A-A-V-S-R-A-S-P-A-Q-S-S-M-V-A-P-F-T-C-L-K-S-T-S-A-F-P-V-T-Q-K-T-N-N-D-I-T-S-I-A-S-N-G-G-R-V-Q-C-M-Q-V-W-P-P-L-G-L-K-K-F-E-T-L-S-Y-L-P-P-L-S-S-E-Q-L-A-K-E-V-D-Y-L-L-R-K-N-L-I-P-C-L-E-F-E-L-E-H-G-F-V-Y-R-E-H-N-R-S-P-G-Y-Y-D-G-R-Y-W-T-M-W-K-L-P-M-F-G-C-N-D-S-S-Q-V-L-K-E-L-E-E-C-K-K-A-Y-P-S-A-F-I-R-I-I-G-F-D-N-K-R-Q-V-Q-I-I-S-F-I-A-Y-K-P-P-G-V"} +{"text": "### FUNCTION May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil Probably interacts with both lipid and phospholipid moieties of lipid bodies May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth ### SEQUENCE -M-A-D-H-H-R-D-R-G-V-L-G-G-G-A-L-G-E-R-G-S-H-G-G-Y-G-Y-T-G-D-H-G-G-Y-G-G-D-D-E-Q-H-Q-Q-K-Q-P-V-M-M-C-A-L-K-A-A-T-A-A-T-A-G-G-S-M-L-V-L-S-G-L-I-L-A-G-T-V-I-A-L-T-V-A-T-P-V-L-V-I-F-S-P-V-L-V-P-A-A-I-S-M-A-L-M-S-A-G-F-V-T-S-G-G-L-G-V-A-A-V-S-V-F-S-W-M-Y-K-Y-L-A-G-K-H-P-P-G-A-D-Q-L-D-H-A-K-A-R-L-A-S-K-A-R-D-I-K-D-A-A-Q-I-R-V-E-Q-A-Q-G-A"} +{"text": "### FUNCTION Major capsid protein that self-associates to form penton base pentamers, each in the shape of a pentagon, situated at the 12 vertices of the pseudo T=25 capsid Involved in virus secondary attachment to host cell after initial attachment by the fiber protein, and in endocytosis of virions As the virus enters the host cell, penton proteins are shed concomitant with virion acidification in the endosome ### SEQUENCE -I-R-N-A-T-L-L-V-T-P-D-V-T-C-G-M-E-Q-V-Y-W-S-I-P-D-M-Y-V-E-P-V-T-F-K-A-S-Q-N-V-S-N-Y-P-V-I-G-V-E-L-M-P-Q-R-P-R-S-F-Y-N-A-Q-A-V-Y-S-Q-M-I-Q-E-N-T-N-Q-T-M-V-F-N-R-F-P-D-N-Q-I-F-L-R-P-P-E-S-T-I-T-S-I-S-E-N-V-P-T-Q-T-D-H-G-T-L-P-I-R-N-S-V-S-G-V-Q-R-V-T-L-T-D-A-R-R-R-A-S-P-Y-V-Y-K-S-I-A-V-A-Q-P-K-V-L-S-S-R-T-F"} +{"text": "### FUNCTION The role of the precursor might be to condense the viral prochromatin for encapsidation by virtue of the two basic domains ### SEQUENCE -M-T-G-V-P-R-V-T-Y-R-V-R-V-P-V-R-T-R-V-L-R-P-R-R-H-G-R-L-V-R-R-V-A-R-R-K-S-M-R-G-G-F-L-P-F-L-V-P-L-I-A-A-A-I-G-A-A-P-G-I-A-S-V-A-L-Q-A-S-R-R"} +{"text": "### FUNCTION Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication E1A protein has both transforming and trans-activating activities Induces the disassembly of the E2F1 transcription factor from RB1 by direct competition for the same binding site on RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes and of the E2 region of the adenoviral genome Release of E2F1 leads to the ARF-mediated inhibition of MDM2 and causes TP53/p53 to accumulate because it is not targeted for degradation by MDM2-mediated ubiquitination anymore This increase in TP53, in turn, would arrest the cell proliferation and direct its death but this effect is counteracted by the viral protein E1B-55K Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection Interaction with RBX1 and CUL1 inhibits ubiquitination of the proteins targeted by SCF ubiquitin ligase complex, and may be linked to unregulated host cell proliferation The tumorigenesis-restraining activity of E1A may be related to the disruption of the host CtBP-CtIP complex through the CtBP binding motif ### SEQUENCE -M-K-L-T-L-E-P-A-P-R-C-L-H-E-Y-V-S-Q-L-L-E-D-W-Q-P-E-C-L-S-C-E-Y-S-H-G-G-S-S-P-P-S-L-H-D-L-F-D-L-E-L-E-N-S-R-S-P-S-P-L-L-C-D-W-C-A-E-A-D-S-E-S-T-I-S-T-E-T-D-V-G-F-T-L-N-T-P-P-V-S-P-L-P-S-Y-S-T-S-P-A-S-I-P-E-D-M-L-L-C-L-E-E-M-P-T-F-D-D-G-D-E-V-R-S-A-T-T-S-F-E-H-W-E-N-N-F-D-P-N-V-G-S-F-F-G-C-L-R-C-A-Y-Y-Q-E-Q-G-E-N-S-I-C-G-L-C-Y-L-K-A-L-A-E-G-K-I-F"} +{"text": "### FUNCTION Increases viral DNA accumulation Enhances infectivity and symptom expression ### SEQUENCE -M-D-S-R-T-G-E-S-I-T-V-A-Q-A-E-N-S-V-F-I-W-E-V-P-N-P-L-Y-F-R-I-Q-R-V-E-D-P-L-Y-T-R-T-R-I-Y-H-I-Q-V-R-F-N-H-N-L-R-K-A-L-D-L-R-K-A-Y-F-N-F-Q-V-W-T-T-S-M-R-A-S-G-P-T-Y-L-S-R-F-K-C-L-V-M-S-H-L-D-N-L-G-V-I-G-I-N-H-V-I-R-A-V-R-F-A-T-D-R-S-Y-V-T-H-V-H-E-N-H-V-I-N-F-K-I-Y"} +{"text": "### FUNCTION Pathogenicity determinant , a mechanism of plant viral defense that limits the accumulation of viral RNAs ### SEQUENCE -M-K-L-F-R-C-F-K-P-C-R-G-Q-S-S-N-P-H-T-S-E-S-Q-E-R-N-I-Q-T-G-S-P-I-Y-T-V-S-S-N-Y-Q-E-S-R-T-S-R-M-L-D-F-S-T-S-L-T-P-E-G-L-P-I-F-T-Q-T-F-R-Q-P-K-T-P-M-P-S-R-I-T-S-P-K-M-V-I-I-V-N-P-G-S-T-R-C-L-G-V-Q-R-Q-I-K-T-T-S-T-T-T-P-S-M-R-D-V-W-K-R-L-S-Q-L"} +{"text": "### FUNCTION Plays an important role in the elongation step of protein synthesis ### SEQUENCE -M-K-Y-V-A-A-Y-L-M-T-V-L-G-G-N-E-A-P-T-A-A-D-V-S-R-V-L-E-P-V-G-A-E-V-N-P-E-V-L-K-T-L-I-D-A-M-Q-G-K-A-A-H-E-V-I-S-A-G-L-E-K-L-Q-K-V-P-C-G-G-G-A-A-A-A-A-P-A-A-A-A-A-A-G-G-G-D-S-S-S-A-A-K-E-T-K-K-E-E-P-E-E-E-E-E-D-G-D-M-G-L-S-L-F-D"} +{"text": "### FUNCTION May be involved in transcriptional regulation ### SEQUENCE -M-E-K-P-Y-N-K-N-E-G-N-L-E-N-E-G-K-P-E-D-E-V-E-P-D-D-E-G-K-S-D-E-E-E-K-P-D-V-E-G-K-T-E-C-E-G-K-R-E-D-E-G-E-P-G-D-E-G-Q-L-E-D-E-G-S-Q-E-K-Q-G-R-S-E-G-E-G-K-P-Q-G-E-G-K-P-A-S-Q-A-K-P-E-S-Q-P-R-A-A-E-K-R-P-A-E-D-Y-V-P-R-K-A-K-R-K-T-D-R-G-T-D-D-S-P-K-D-S-Q-E-D-L-Q-E-R-H-L-S-S-E-E-M-M-R-E-C-G-D-V-S-R-A-Q-E-E-L-R-K-K-Q-K-M-G-G-F-H-W-M-Q-R-D-V-Q-D-P-F-A-P-R-G-Q-R-G-V-R-G-V-R-G-G-G-R-G-Q-R-G-L-H-D-I-P-Y-L"} +{"text": "### FUNCTION Binds and inhibits cysteine proteinases Inhibits most strongly papain and cathepsin L, more weakly bromelain and cathepsin B while it is completely ineffective against cathepsin H ### SEQUENCE -M-A-S-L-E-D-G-I-Y-R-L-R-A-V-T-T-H-N-P-D-P-G-V-G-G-E-Y-A-T-V-E-G-A-R-Q-P-V-K-A-E-P-S-T-P-P-F-F-E-R-Q-I-W-Q-V-T-R-N-S-D-G-Q-S-T-I-K-Y-Q-G-L-N-T-P-F-E-Y-G-F-S-Y-D-Q-L-E-Q-N-A-P-V-I-A-G-D-P-K-E-Y-I-L-Q-L-V-P-S-T-T-D-V-Y-I-I-R-A-P-I-Q-R-V-G-V-D-V-E-V-G-V-Q-G-N-N-L-V-Y-K-F-F-P-V-D-G-S-G-G-D-R-P-A-W-R-F-T-R-E"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-T-D-V-Q-L-Q-N-I-V-T-T-F-G-I-S-M-M-L-L-I-I-L-Y-H-Y-L-S-R-P-Q-A"} +{"text": "### FUNCTION Facilitates protein transport into the nucleus Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import ### SEQUENCE -M-A-D-F-Q-S-I-A-Q-Q-F-V-T-F-Y-Y-Q-T-F-D-G-N-R-A-G-L-A-P-L-Y-R-D-H-S-M-L-T-F-E-T-S-A-I-Q-G-V-A-G-I-I-E-K-L-T-S-L-P-F-Q-K-V-Q-H-Q-V-S-T-L-D-A-Q-P-S-G-E-H-G-G-I-L-V-L-V-T-G-A-L-L-V-D-E-E-K-N-P-M-N-Y-T-Q-T-F-Q-L-M-P-D-G-A-G-S-Y-F-V-L-N-D-V-F-R-L-I-Y-N-A"} +{"text": "### FUNCTION Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner It has the ability to bind G- and F-actin in a 11 ratio of cofilin to actin Binding to F-actin is regulated by tropomyosin It is the major component of intranuclear and cytoplasmic actin rods Required for accumulation of actin at the cell division site via depolymerizing actin at the cell ends In association with myosin II has a role in the assembly of the contractile ring via severing actin filaments Involved in the maintenance of the contractile ring once formed In association with profilin and capping protein, has a role in the mitotic reorganization of the actin cytoskeleton ### SEQUENCE -M-S-R-S-G-V-A-V-S-D-E-A-L-K-A-F-N-D-L-K-L-G-K-K-F-K-S-I-I-Y-K-L-N-D-A-K-T-E-I-V-V-D-S-T-S-T-E-D-A-Y-D-A-F-V-E-D-L-P-E-N-D-C-R-Y-A-V-Y-D-F-E-Y-E-V-G-Q-G-D-G-K-R-N-K-I-V-F-Y-Q-W-S-P-D-T-A-S-V-R-A-K-M-V-Y-A-S-S-K-D-A-L-R-R-A-L-N-G-I-G-T-E-I-Q-G-T-D-F-S-E-V-A-Y-E-S-V-L-E-K-I-S-R-T-T-G-L-H"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-T-R-T-S-V-L-A-D-A-L-N-A-I-N-N-A-E-K-T-G-K-R-Q-V-L-I-R-P-S-S-K-V-I-I-K-F-L-T-V-M-Q-K-H-G-Y-I-G-E-F-E-Y-I-D-D-H-R-S-G-K-I-V-V-Q-L-N-G-R-L-N-K-C-G-V-I-Q-P-R-F-N-V-K-I-N-D-I-E-R-W-T-D-N-L-L-P-A-R-Q-F-G-Y-V-I-L-T-T-S-A-G-I-M-D-H-E-E-A-R-R-K-H-V-S-G-K-I-L-G-F-V-Y"} +{"text": "### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-K-P-K-P-S-Q-F-K-N-L-E-R-M-L-G-L-K-T-E-Q-L-D-A-V-K-V-T-I-E-L-K-D-K-I-L-I-I-E-N-P-T-V-I-K-M-I-A-Q-G-Q-E-I-Y-S-V-I-G-E-A-K-E-A-Q-K-E-E-P-K-V-E-I-K-D-E-D-V-K-F-V-M-E-Q-T-G-K-G-E-Q-E-V-K-E-A-L-Q-K-A-N-G-D-I-A-K-A-I-L-L-L-T-G-Q-E-T"} +{"text": "### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-Q-T-R-L-R-V-Y-I-T-G-E-P-G-V-G-K-T-T-I-F-L-K-V-I-D-K-L-K-S-Q-G-Y-S-I-S-G-F-Y-C-P-E-V-R-E-K-G-Q-R-I-G-F-K-I-K-S-L-D-N-E-V-E-D-W-L-A-S-I-Y-A-K-S-S-I-K-I-G-K-Y-Y-I-T-I-N-E-D-I-I-N-K-I-K-E-K-I-S-K-S-E-I-I-G-I-D-E-I-G-P-M-E-L-S-V-P-K-L-K-E-I-I-D-Y-V-L-N-E-K-P-I-V-V-A-V-V-H-R-K-I-S-F-K-D-G-K-T-F-V-V-T-Y-E-N-R-N-R-L-D-N-E-I-F-N-Y-I-I-S-S-I-Q"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-S-Q-Q-Q-Q-F-K-Y-I-V-R-L-F-G-Q-D-V-D-G-T-M-K-V-P-Y-A-L-A-M-V-K-G-I-G-Y-N-T-A-R-A-I-V-F-K-L-G-L-D-K-D-R-R-L-G-E-L-S-D-E-D-I-K-K-I-E-N-Y-L-T-D-K-K-I-L-E-V-P-N-W-M-Y-N-R-R-K-D-Y-E-S-G-I-D-M-H-L-V-T-S-D-L-I-F-Y-V-R-N-D-I-E-R-E-K-K-I-K-S-W-R-G-V-R-H-S-L-G-L-K-V-R-G-Q-R-T-R-T-T-G-R-T-G-V-T-V-G-V-R-R-S-K-A-A-Q-A-A-Q-Q-Q-Q-K-A-Q-A-S-S-G-G-E-K-K-Q-G"} +{"text": "### FUNCTION Located on the platform of the 30S subunit ### SEQUENCE -M-S-S-R-R-E-I-R-W-G-I-A-R-V-Y-A-S-Q-N-N-T-L-I-T-I-T-D-I-T-G-A-E-I-I-S-R-A-S-G-G-M-V-V-K-A-D-R-E-K-P-S-P-Y-A-A-M-L-A-A-N-K-A-A-T-E-A-F-D-K-G-I-S-A-I-H-I-K-V-R-A-Q-G-G-Y-G-S-K-T-P-G-P-G-A-Q-P-A-I-R-A-L-A-R-A-G-F-I-I-G-R-I-E-D-V-T-P-I-P-H-D-S-I-R-R-P-G-G-R-R-G-R-R-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-S-E-Q-L-V-V-V-N-A-E-N-Q-I-L-G-R-M-A-T-H-I-A-K-L-L-I-Q-G-K-R-V-V-V-V-N-A-E-K-A-I-I-S-G-P-R-A-R-V-V-R-G-Y-S-L-I-F-S-V-R-K-F-Q-N-P-E-K-N-T-I-K-R-P-R-T-P-I-N-I-V-K-R-T-V-R-G-M-L-P-K-N-K-S-G-K-M-M-F-K-N-L-I-V-F-I-G-I-P-A-E-Y-K-D-K-Q-M-I-R-F-E-D-A-D-V-K-R-L-K-G-K-Y-I-T-V-G-E-L-S-K-L-L-G-G-F-S-Q"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-N-V-S-N-C-E-I-P-E-N-L-L-Y-F-I-E-G-K-N-T-V-W-A-K-Q-E-A-P-D-V-I-V-V-G-I-T-D-I-A-Q-T-M-A-G-K-V-V-K-V-R-L-K-K-K-G-T-K-V-E-R-G-K-P-V-A-T-M-E-S-G-K-W-A-G-P-V-P-A-P-A-S-G-E-I-I-D-V-N-P-D-V-E-K-N-P-V-L-V-N-Q-D-P-Y-G-K-G-W-L-V-K-M-K-V-N-N-P-E-E-L-K-Q-L-V-T-G-S-A-A-V-S-K-L-T-E-L-I-N-S-E-K-L-Q-C-K-R-L"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-Q-V-E-G-F-E-F-P-D-E-L-Y-Y-Y-P-E-E-H-V-W-V-K-I-E-G-D-M-V-T-V-G-I-T-S-L-G-Q-Y-M-A-G-K-I-F-Q-V-T-T-K-N-K-G-E-K-V-T-P-K-S-V-I-F-T-L-E-S-A-K-W-I-G-K-F-R-L-P-V-E-G-E-I-V-D-I-N-D-E-V-V-K-N-P-T-L-I-N-E-K-P-Y-D-A-W-I-V-K-I-K-G-D-I-K-K-E-K-L-L-P-V-S-E-A-V-K-I-F-E-N-D-A-K-R-V-I-R"} +{"text": "### FUNCTION Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7 ### SEQUENCE -M-R-L-P-G-I-P-D-E-E-F-I-R-V-E-K-I-P-M-T-K-E-E-I-R-V-L-A-L-S-K-A-R-L-F-D-G-A-K-F-I-D-I-G-S-G-T-G-S-V-T-V-E-A-G-L-V-V-G-E-K-G-K-V-W-A-I-E-K-D-K-D-A-V-E-L-T-K-K-N-V-E-K-F-K-L-N-N-V-V-I-I-E-G-E-A-P-E-A-L-D-H-V-D-S-E-V-D-A-I-F-I-G-G-T-E-R-L-E-E-I-L-L-S-S-D-K-K-L-K-N-G-G-R-I-V-I-D-A-I-L-L-E-T-V-N-K-A-L-S-T-L-N-Q-M-G-Y-K-T-D-V-I-E-V-I-I-A-K-G-M-K-T-S-K-G-Y-A-M-I-S-R-N-P-I-F-I-V-Y-G-E-K-P"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-D-F-I-K-S-L-V-E-N-K-L-L-L-I-G-N-F-V-L-T-S-G-K-I-S-P-Y-Y-L-D-L-R-R-L-S-N-Y-Y-E-I-F-S-D-T-V-N-K-A-I-D-K-I-K-N-I-D-F-D-M-I-I-G-I-A-T-G-G-I-P-F-A-S-F-I-S-C-R-M-G-K-P-L-G-Y-I-R-M-E-K-K-G-Y-G-T-D-K-I-L-E-A-D-V-S-G-R-K-I-L-L-V-D-D-V-A-T-T-G-G-S-L-S-K-A-V-E-I-I-N-S-E-G-G-R-V-V-A-S-L-V-I-V-D-R-E-E-G-A-E-K-K-L-G-E-Y-G-V-K-L-I-S-V-Y-K-I-R-E-I-L-E-Y-L-L-N-S-S-L-I-S-D-N-D-K-N-N-I-K-E-Y-L-V-K-N-I-E"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-E-T-V-N-K-K-E-L-I-V-S-K-I-K-N-G-T-V-I-D-H-I-P-A-G-R-A-L-A-V-L-R-I-L-K-I-A-E-G-Y-R-I-A-L-V-M-N-V-E-S-K-K-M-G-K-K-D-I-V-K-I-E-N-K-E-V-D-E-K-E-A-N-L-I-T-L-I-A-P-T-A-T-I-N-I-I-R-D-Y-E-V-V-E-K-K-K-L-K-I-P-D-I-V-K-G-L-L-K-C-T-N-L-M-C-I-T-N-N-D-V-E-A-I-P-G-F-K-K-I-S-E-K-P-L-K-M-K-C-V-Y-C-D-T-V-I-D-E-N-E-I-L-K-Q-I-L-G-S-K-S"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-S-N-E-E-N-Q-Q-K-V-V-V-S-L-E-D-L-L-A-Q-A-D-A-L-K-K-Y-I-D-Y-L-Q-K-T-Y-A-E-L-Q-D-N-I-M-S-I-D-S-S-L-Q-A-L-K-E-L-Q-N-S-Q-E-L-L-M-V-G-D-K-R-G-N-V-I-F-K-V-Q-G-I-D-K-A-K-V-L-V-H-L-G-L-E-Y-Y-A-E-V-D-P-D-F-A-T-K-V-L-N-D-K-K-S-E-L-S-N-V-L-S-N-V-E-K-E-L-A-K-S-L-E-A-Y-K-E-I-A-D-I-L-N-Q-A-Q-Q-Q-L-Q-A-Q-Q-N-K-G-G"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-S-L-S-Q-R-L-K-N-L-R-E-D-W-K-R-I-I-S-V-A-K-K-P-E-K-D-T-L-N-Q-S-I-K-L-T-L-L-V-M-A-I-V-G-I-I-A-Y-I-I-Q-L-T-V-A-L-L-L-H"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-P-T-K-S-I-K-I-V-V-E-G-G-N-V-K-P-G-P-P-L-A-P-T-L-S-Q-L-G-L-N-V-G-E-V-V-K-K-I-N-D-A-T-S-Q-F-K-G-M-S-V-P-V-T-L-E-V-D-T-D-T-K-K-Y-E-I-K-V-G-I-P-T-T-T-S-L-L-L-K-F-A-N-A-S-E-P-S-G-D-P-A-H-K-K-V-G-D-I-K-F-E-D-I-I-Q-V-A-I-M-K-K-P-Q-I-T-A-K-T-L-K-A-A-V-K-S-I-L-G-T-A-H-S-I-G-L-T-V-D-K-K-S-P-K-E-L-V-K-A-V-D-E-G-K-Y-D-D-L-L-A-K-Y-E-Q-K-W-N-E-A-E-G"} +{"text": "### FUNCTION Functions by promoting the formation of the first peptide bond ### SEQUENCE -M-S-I-Q-Y-T-T-V-G-D-L-K-V-G-N-Y-V-V-I-D-G-E-P-C-R-V-V-E-I-S-K-A-K-T-G-K-H-G-S-A-K-A-N-I-V-A-I-G-L-F-T-G-Q-K-R-T-L-M-A-P-V-D-Q-Q-V-E-V-P-I-I-E-K-H-I-G-Q-I-L-A-D-K-G-D-T-I-T-I-M-D-M-E-N-Y-E-T-F-D-I-E-K-P-T-D-A-D-I-V-D-K-I-R-P-G-A-E-V-E-Y-W-E-I-M-G-R-K-K-I-V-R-V-K"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-T-V-K-K-P-N-E-I-L-I-S-R-T-K-R-V-E-D-Y-V-L-D-V-I-V-M-F-N-Q-G-Y-D-E-V-E-L-K-G-V-G-N-S-I-Y-K-A-V-E-V-Y-N-Q-L-K-D-R-L-G-D-G-I-I-L-E-K-A-D-I-G-S-E-V-K-D-R-R-R-I-S-Y-I-S-I-K-L-K-R-V-Y"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-S-S-T-A-T-P-T-P-S-N-V-V-L-V-G-K-K-P-V-M-N-Y-V-L-A-A-L-T-L-L-N-Q-G-V-S-E-I-I-I-K-A-R-G-R-A-I-S-K-A-V-D-T-V-E-I-V-R-N-R-F-L-P-D-K-I-E-V-K-E-I-R-I-G-S-Q-V-V-T-S-Q-D-G-R-Q-S-R-V-S-T-I-E-I-A-I-R-K-K-A"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-K-I-E-V-N-N-E-L-I-S-R-L-Q-N-L-A-L-V-E-L-N-D-R-E-K-E-R-I-K-R-D-I-K-N-I-L-D-F-F-D-Q-I-N-K-L-D-L-S-N-V-E-P-L-F-H-P-I-S-T-G-K-L-R-K-D-E-I-I-K-P-L-S-R-D-E-A-L-S-N-V-K-R-K-E-D-G-F-I-V-G-P-A-T-Y-G-E"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-T-N-I-P-E-I-P-Y-K-A-V-V-N-I-E-N-I-V-A-T-V-T-L-D-Q-N-L-D-L-Y-A-M-E-R-S-V-P-N-V-E-Y-D-P-D-Q-F-P-G-L-I-F-R-L-E-A-P-K-V-T-S-L-I-F-K-S-G-K-M-V-V-T-G-A-K-S-T-D-E-L-I-K-A-V-K-R-I-I-K-T-L-K-R-Y-G-M-N-L-T-G-K-P-K-I-Q-I-Q-N-I-V-A-S-A-N-L-H-V-I-V-N-L-D-K-A-A-F-L-L-E-N-N-M-Y-E-P-E-Q-F-P-G-L-I-Y-R-M-E-D-P-R-V-V-L-L-I-F-S-S-G-K-M-V-I-T-G-A-K-R-E-E-E-V-H-K-A-V-K-K-I-F-D-K-L-V-E-L-D-C-V-K-P-F-E-E-E-E-L-E-F"} +{"text": "### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates ### SEQUENCE -M-S-I-N-K-I-F-E-E-S-W-K-N-R-L-T-K-Y-E-I-A-R-I-I-S-A-R-A-L-Q-L-A-M-G-A-S-P-L-I-D-T-N-N-L-P-F-N-D-V-I-S-I-A-E-E-E-L-K-R-G-V-L-P-I-T-V-R-R-V-Y-P-N-G-K-I-E-L-V-S-V-K-K-V-E-F-K"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-E-I-I-V-G-G-K-Y-K-V-L-K-D-R-Y-Y-S-E-T-D-E-W-I-L-V-K-E-N-I-A-I-V-G-I-T-D-Y-A-Q-K-K-L-R-D-I-V-G-V-E-L-P-E-I-D-K-E-V-K-A-N-D-P-V-A-V-V-E-S-V-K-A-A-A-D-I-Y-S-P-L-S-G-K-V-I-E-T-N-Q-K-L-T-E-S-P-E-L-I-N-K-D-P-Y-G-E-G-W-I-F-K-L-E-I-S-D-R-N-E-I-E-K-L-L-S-P-E-K-Y-S-E-L-I-K-Q-R-E-G-L"} +{"text": "### FUNCTION Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide ### SEQUENCE -M-I-D-K-K-E-L-R-E-I-S-L-K-K-K-R-E-K-R-L-T-W-E-E-I-G-K-Y-L-G-R-D-K-V-Y-A-A-M-L-L-Y-G-Y-A-Q-A-T-E-E-E-A-D-K-I-I-T-L-L-D-L-P-K-E-L-K-P-A-F-L-D-A-P-M-R-T-P-A-Q-P-W-P-P-T-D-P-F-I-Y-R-L-Y-E-G-V-L-L-Y-G-P-V-I-K-D-V-A-H-E-L-F-G-D-G-I-M-S-M-I-D-V-K-I-Y-V-D-K-V-I-E-N-N-Y-P-R-M-V-L-T-F-N-G-K-W-L-Y-Y-S-K-W"} +{"text": "### FUNCTION Involved in ribosome biogenesis ### SEQUENCE -M-K-W-K-I-K-K-C-P-K-D-C-T-Y-T-L-K-D-I-C-P-I-C-G-T-P-T-I-I-P-H-P-A-R-F-S-P-V-D-K-Y-V-K-Y-R-I-E-I-K-K-G-I-K-L-N-C"} +{"text": "### FUNCTION Degrades oligopeptides in a sequential manner ### SEQUENCE -M-T-I-T-K-R-K-N-T-F-Y-T-S-Q-F-I-S-Y-M-K-G-Y-Y-L-H-P-D-I-R-G-N-L-V-A-F-T-S-D-D-D-V-W-L-M-T-L-E-D-M-K-P-I-R-V-T-S-G-Q-G-V-A-I-R-P-K-I-S-P-D-G-K-K-I-A-Y-T-I-I-W-L-R-K-G-K-G-G-G-D-I-F-I-T-G-N-G-E-T-K-R-I-T-F-F-G-S-M-N-T-R-V-L-G-W-L-S-D-D-E-I-L-V-L-T-D-F-H-T-P-F-P-Q-W-S-E-T-Y-K-I-N-I-N-D-G-T-M-E-K-I-P-F-G-P-I-S-N-I-A-I-S-G-D-I-I-V-I-A-R-G-Y-Q-D-L-P-F-W-K-G-Y-K-G-G-T-K-G-E-F-L-I-S-Y-D-K-G-N-T"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-I-V-E-G-K-V-L-K-F-G-D-K-I-D-T-D-I-I-I-P-A-R-Y-L-K-Y-T-D-P-Q-Y-L-A-Q-H-A-M-E-P-L-D-P-E-F-Y-K-K-A-S-A-G-V-I-L-V-A-G-K-V-F-G-M-G-S-S-R-E-Q-A-A-I-A-L-K-A-A-G-V-R-A-I-I-A-E-S-F-A-R-I-F-Y-R-N-A-I-N-N-G-L-P-A-I-V-L-P-G-V-T-Q-L-I-N-E-G-D-Y-V-K-I-N-V-E-T-G-E-I-I-V-N-N-Q-K-V-Y-K-G-R-G-I-T-G-M-P-L-K-I-L-E-S-G-G-L-L-D-Y-L-K-K-V-S-V-Q-N-Q-G-G-N"} +{"text": "### FUNCTION Catalyzes the synthesis of GMP from XMP ### SEQUENCE -M-K-I-A-V-I-Y-F-G-G-Q-Y-N-H-L-I-V-K-D-L-K-Y-L-G-L-N-A-V-L-I-T-P-E-K-P-V-E-I-L-K-D-Y-D-C-I-I-F-G-G-G-P-Y-S-V-I-T-E-L-N-K-M-G-N-A-V-D-Y-V-L-R-T-S-Q-P-K-L-G-I-C-L-G-H-Q-L-L-A-K-V-L-G-G-E-V-T-K-A-T-K-P-E-Y-G-L-V-K-V-N-I-N-D-E-D-T-I-L-R-G-L-S-P-S-I-N-A-W-E-S-H-T-D-E-V-I-S-P-P-Q-G-F-R-I-L-A-N-S-E-N-A-K-V-Q-A-M-V-N-K-D-N-T-I-F-G-V-Q-F-H-P-E-V-K-H-T-E-K-G-I-E-V-F-K-N-F-I-E-A-C-K-K"} +{"text": "### FUNCTION eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA ### SEQUENCE -M-S-T-E-E-E-Y-I-K-L-L-D-R-L-Y-S-K-L-P-E-R-V-Q-K-V-S-G-Q-S-L-P-N-L-I-I-L-S-I-G-N-N-T-I-I-K-N-F-S-E-Y-C-D-R-I-R-R-E-D-K-L-C-A-K-F-I-L-K-E-L-A-A-P-G-N-V-D-E-N-G-Q-L-V-I-Q-G-K-F-S-S-A-S-I-N-K-I-M-E-R-F-I-K-T-Y-V-Q-C-S-T-C-K-S-L-D-T-V-L-I-K-E-K-K-A-W-Y-I-S-C-L-A-C-G-A-K-T-P-V-K-P-L"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-A-K-K-K-T-N-E-Q-P-S-V-K-E-V-P-K-P-A-E-G-E-V-I-C-V-V-K-K-M-L-G-A-E-H-V-Q-V-I-C-L-D-G-K-E-R-L-G-R-I-P-G-K-M-K-K-K-M-W-V-K-E-G-D-V-V-L-A-A-P-W-D-F-Q-P-N-K-C-D-I-I-Y-K-Y-S-E-S-E-V-R-R-L-E-E-E-Q-V-V-S-A-D-I-I-E-Q-L-R-G"} +{"text": "### FUNCTION Catalyzes the formation of CDP-2,3-bis- and CTP This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-P-I-I-Y-Y-V-I-F-A-I-L-Y-Y-L-P-A-L-V-A-N-G-S-A-P-F-V-K-N-G-T-P-I-D-F-R-K-N-F-V-D-G-R-R-L-L-G-D-G-K-T-F-E-G-L-L-V-A-V-T-F-G-T-T-V-G-I-I-L-A-K-F-L-G-I-Y-W-I-Y-V-S-F-I-E-S-L-L-A-M-L-G-D-M-V-G-A-F-I-K-R-R-L-G-L-A-R-G-A-R-A-I-G-L-D-Q-L-D-F-I-L-G-A-T-L-A-L-I-I-S-K-I-S-L-N-I-Y-E-F-L-S-I-V-V-I-A-F-V-L-H-I-L-T-N-N-V-A-Y-R-L-K-I-K-S-V-P-W"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-V-I-F-S-Y-R-T-R-I-I-Y-I-K-K-I-K-N-K-R-D-T-R-A-K-R-Y-V-I-F-D-I-I-S-E-D-N-F-E-I-R-E-I-E-E-A-V-R-N-S-V-K-E-L-G-G-K-I-W-L-D-L-S-N-P-K-V-I-M-I-Y-N-N-R-G-I-I-S-T-N-R-I-G-Y-K-I-I-I-A-S-L-P-L-I-K-K-I-K-N-K-E-V-L-L-V-P-R-R-T-T-G-S-L-K-R-A-K-R-L-I-G-I-E"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-T-E-R-I-P-P-E-L-Q-T-Q-L-V-K-L-Q-Q-L-Q-D-Q-L-N-R-L-L-T-E-K-N-V-I-D-S-E-L-R-E-V-N-K-I-L-Q-E-L-S-Q-L-P-A-G-T-T-V-Y-K-I-V-G-N-L-L-V-K-T-D-K-E-T-V-Q-K-E-L-D-D-R-K-E-I-L-E-L-R-S-R-T-Y-Q-K-Q-E-N-L-L-R-T-Q-L-E-D-L-Q-K-K-V-N-E-L-L-A-K-Y-Y-P-Q-S-G-G-A-I-K-A"} +{"text": "### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-I-I-K-E-F-L-T-T-E-K-A-I-K-L-I-E-S-Q-N-T-L-T-V-I-V-N-K-E-A-T-K-A-D-I-K-R-E-I-E-K-M-F-N-V-K-V-D-K-V-N-T-L-I-T-I-R-G-E-K-K-A-Y-V-K-L-K-K-E-F-N-A-S-D-I-A-H-R-L-G-I-L"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-L-E-I-P-P-E-W-K-K-F-R-Y-R-G-K-S-L-D-E-L-L-N-M-P-M-D-E-F-I-K-L-L-P-S-R-Q-R-R-S-L-K-K-G-F-S-D-K-Q-R-R-L-L-E-K-I-R-K-Y-V-R-E-G-K-Y-S-K-T-I-K-T-H-V-R-D-M-I-I-L-P-E-M-V-G-L-K-F-A-V-Y-N-G-K-E-F-V-E-F-Q-V-V-P-E-M-I-G-H-Y-L-G-E-F-S-I-T-T-K-K-V-E-H-G-E-P-G-L-K-A-T-R-S-S-L-F-L-A-M-K-G"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-A-G-W-T-Y-P-K-L-D-I-D-E-N-K-L-A-K-A-V-I-K-N-V-P-A-S-I-R-D-L-Y-N-V-C-K-A-I-R-G-M-K-L-N-D-A-K-Q-F-L-N-N-V-L-E-E-K-E-A-L-P-F-W-K-H-S-H-G-A-S-H-R-S-N-I-S-P-K-W-K-V-K-S-G-R-Y-P-K-K-A-I-K-Y-V-L-K-V-L-E-N-A-E-N-N-A-N-S-K-G-L-D-L-E-N-V-K-I-V-H-I-A-A-H-K-G-I-I-L-K-R-Y-M-P-R-A-F-G-R-S-T-R-K-Y-R-Y-T-S-H-I-E-V-I-L-G-E-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-G-K-K-G-A-L-V-K-N-I-G-I-E-G-V-N-P-P-S-K-T-C-D-D-I-N-C-P-F-H-G-N-L-R-V-R-G-I-I-L-E-G-R-L-I-R-Y-R-A-E-K-T-G-V-V-E-R-D-Y-L-F-Y-D-T-K-Y-K-R-Y-E-R-R-R-S-R-I-H-V-H-I-P-P-C-L-D-V-K-E-G-D-N-V-I-I-A-E-C-R-P-I-A-K-S-V-S-F-V-V-I-G-K-R"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-P-E-K-L-Q-V-L-G-S-R-K-G-L-T-P-G-L-Q-H-Y-T-T-V-T-V-A-D-N-S-G-A-K-E-A-V-I-I-G-I-Y-G-Y-K-G-V-L-R-R-I-P-F-A-N-I-A-D-L-V-M-V-S-V-R-K-G-T-P-E-V-R-K-Q-K-F-K-A-V-I-V-R-Q-R-M-P-F-R-R-P-D-G-T-W-I-A-F-E-D-N-A-V-V-I-V-N-P-D-G-T-P-K-G-T-E-I-R-G-P-I-A-K-E-A-A-E-R-W-P-K-V-A-S-I-A-T-M-V-I"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-V-S-H-K-P-S-K-Q-R-L-L-L-Y-N-L-P-K-H-Q-R-H-K-L-L-T-A-K-L-S-K-E-L-Q-Q-Q-Y-G-I-K-R-L-A-I-R-K-G-D-T-V-K-V-M-R-G-D-K-D-V-L-N-F-E-G-K-V-V-E-V-N-R-K-T-G-R-I-A-I-E-G-L-T-R-K-K-A-D-G-T-P-V-Y-R-W-I-H-A-S-K-V-I-I-T-K-L-D-L-S-D-A-K-R-K-E-I-I-E-R-K-R-K-A-R-E-E-Y-L-K-K-K-E-Q-T-T-E-A-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-E-T-Q-T-V-N-P-M-R-K-L-R-L-E-K-V-T-V-N-I-G-V-G-E-A-G-E-R-L-Q-K-A-Y-Q-L-L-Q-E-L-T-G-V-K-P-V-Y-T-I-A-K-R-T-I-R-E-F-G-V-R-K-G-A-P-I-G-V-K-V-T-L-R-G-K-K-A-E-E-F-L-N-K-V-L-A-A-V-G-H-R-I-K-A-S-S-F-D-E-Y-G-N-V-S-F-G-I-A-E-H-V-L-I-P-G-T-R-Y-D-P-E-I-G-I-F-G-M-D-V-A-I-T-L-V-R-P-G-F-R-V-A-R-R-R-R-K-K-A-H-I-P-K-R-H-R-T-V-S-K-E-E-A-M-E-F-L-K-Q-N-F-N-V-T-I-V-E-G"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-G-K-Y-K-P-P-A-E-R-K-Y-G-R-G-V-Q-V-C-R-R-C-G-S-R-D-S-V-I-Q-K-Y-G-L-Y-L-C-R-Q-C-F-R-E-V-A-Y-E-M-G-F-K-K-T-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-N-L-N-P-L-A-N-A-L-T-T-I-Y-N-N-E-M-R-R-N-K-Q-A-I-I-M-P-A-S-K-L-I-I-N-V-L-R-A-M-Q-K-E-G-Y-I-G-E-F-E-F-I-D-D-G-R-S-G-K-I-V-V-Q-L-L-G-R-I-N-K-C-G-P-I-A-P-R-Y-P-L-K-Y-K-D-L-L-T-L-P-D-Y-V-R-R-Y-L-P-S-K-E-I-G-V-L-I-I-S-T-N-K-G-V-M-T-H-K-D-A-I-R-E-R-I-G-G-V-A-L-G-Y-V-Y"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-K-A-V-H-L-Y-E-E-I-E-I-P-Q-G-I-N-V-N-I-E-G-M-K-I-K-V-K-G-P-K-G-E-I-E-K-D-F-S-H-I-S-G-I-E-I-R-K-E-D-N-K-I-V-V-E-T-T-F-A-D-R-R-K-K-A-Q-F-Y-S-I-I-A-H-I-E-N-M-F-T-G-V-T-K-G-Y-R-Y-Y-L-K-I-I-Y-T-H-F-P-V-T-V-K-V-S-G-N-E-V-Q-I-Q-N-L-I-G-E-K-N-I-R-R-A-K-I-M-T-G-V-K-V-N-V-K-G-E-D-I-I-V-E-G-Q-D-I-E-K-V-G-Q-T-A-A-N-I-E-L-A-S-K-I-T-G-Y-D-R-R-V-F-A-D-G-I-Y-I-Y-K-K-E-V-I-G-S-E-Q-T-D"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-H-G-P-N-Y-R-V-K-Y-R-R-R-R-E-G-K-T-N-Y-Y-K-R-Y-T-Y-V-I-N-N-T-T-R-L-V-V-R-L-T-N-K-Y-I-I-A-Q-I-A-K-F-N-P-K-G-D-V-I-V-V-A-A-H-S-M-E-L-A-K-K-F-G-W-K-G-D-L-N-N-T-P-A-A-Y-L-T-G-Y-L-L-G-V-R-A-L-K-A-G-I-K-E-A-V-A-D-I-G-L-F-V-P-V-K-G-S-R-I-F-T-A-I-K-G-A-I-D-A-G-L-S-I-P-V-G-D-L-G-I-K-E-D-R-I-K-G-V-H-I-A-S-Y-A-Q-K-L-E-A-E-N-P-E-L-F-K-R-L-F-S-K-Y-L-E-R-G-L-H-P-K-D-L-P-S-H-F-E-E-I-L-N-K-I-K-S-G-G-A"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently ### SEQUENCE -M-Q-K-F-E-F-F-E-H-T-A-D-I-G-I-R-A-Y-G-R-N-L-N-E-A-F-E-N-A-A-V-A-V-F-E-V-M-T-D-T-S-K-V-E-P-K-E-M-R-E-V-K-I-D-G-Y-D-L-E-N-L-L-Y-R-W-I-E-S-L-L-V-Y-Y-D-S-E-I-M-L-F-S-K-F-Y-V-N-I-D-E-K-N-L-T-L-E-G-K-A-W-G-E-K-F-D-P-N-K-H-E-R-R-T-V-V-K-A-M-T-Y-H-E-M-K-I-E-N-K-G-N-Y-Y-I-L-T-F-V-V-D-I"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-P-D-Q-S-I-N-L-A-I-V-V-A-E-F-N-Y-D-I-T-Y-L-M-L-Q-R-A-I-A-H-A-K-F-L-G-A-N-V-K-V-V-F-K-V-P-G-S-Y-D-M-A-I-A-V-K-E-L-L-K-R-D-D-I-D-A-V-V-T-L-G-A-V-I-K-G-E-T-K-H-D-E-I-V-A-T-Q-T-A-R-K-I-L-D-L-S-V-E-Y-G-K-P-V-T-L-G-I-I-G-H-G-V-T-H-E-Q-A-V-E-R-I-E-E-Y-S-T-R-A-V-E-A-A-I-K-L-A-K-R-L-R-E-L-R-K-I-Q-T-L-N-E-E-M-V-V-I-E"} +{"text": "### FUNCTION Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A ### SEQUENCE -M-P-D-S-I-K-K-E-L-T-R-P-Y-G-F-L-F-T-N-N-D-I-F-I-N-F-I-L-E-K-K-N-N-R-L-I-T-V-G-D-V-V-T-S-T-L-Y-D-R-N-I-I-P-F-L-S-I-I-D-G-K-T-K-R-Q-I-K-V-K-T-V-N-E-N-V-I-K-V-K-N-E-K-S-T-I-R-F-S-V-M-K-I-I-K-N-L-L-D-K-N-E-R-A-T-I-L-V-D-G-E-E-D-L-L-V-I-P-V-V-I-F-G-R-N-N-D-I-I-V-Y-G-Q-P-N-A-G-A-V-V-I-I-N-N-H-F-V-K-I-R-V-K-Q-I-L-E-K-F-Y-V-K-K-C"} +{"text": "### FUNCTION Endonuclease that removes tRNA introns Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp ### SEQUENCE -M-I-G-E-L-V-K-D-K-I-L-I-K-N-I-E-D-A-R-L-I-Y-K-M-G-Y-Y-G-K-P-I-G-I-S-K-P-K-S-A-E-E-I-N-S-E-L-I-L-S-L-I-E-G-V-Y-L-V-K-K-G-K-L-E-I-V-S-N-G-E-R-L-D-F-E-R-L-Y-Q-I-G-V-T-Q-I-P-R-F-R-I-L-Y-S-V-Y-E-D-L-R-E-K-G-Y-V-V-R-S-G-I-K-Y-G-A-D-F-A-V-Y-T-I-G-P-G-I-E-H-A-P-Y-L-V-I-A-L-D-E-N-S-Q-I-S-S-N-E-I-L-G-F-G-R-V-S-H-S-T-R-K-E-L-I-L-G-I-V-N-L-T-N-G-K-I-R-Y-I-M-F-K-W-L-K-M"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-G-T-P-S-F-G-K-M-N-K-S-P-T-H-V-R-C-R-R-C-G-R-N-S-F-N-V-R-K-G-Y-C-A-A-C-G-F-G-R-S-K-K-I-R-R-Y-N-W-Q-N-K-K-V-N-G-L-R-L-V"} +{"text": "### FUNCTION Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein and RNA polymerase recruitment Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes ### SEQUENCE -M-S-S-R-A-E-E-L-I-L-S-L-A-K-D-L-V-G-E-D-A-T-E-L-L-K-F-L-L-R-K-R-I-E-M-T-D-D-D-I-A-K-E-L-N-V-K-V-N-E-I-R-K-K-L-Y-L-L-S-E-Q-G-F-I-T-Y-R-K-T-R-D-K-E-T-G-L-F-I-Y-Y-W-K-V-N-I-D-Q-I-N-E-L-L-L-N-R-K-R-L-V-L-E-K-L-K-A-R-Y-E-Q-E-K-D-S-L-Y-Y-Y-C-P-Q-D-N-I-Q-Y-N-F-D-E-A-L-E-N-E-F-K-C-P-K-C-G-S-P-L-E-Y-Y-D-S-E-K-T-K-K-F-L-E-Y-K-I-K-Q-I-E-N-E-I-E-R-E-T-R-H-G-S-N-S-R"} +{"text": "### FUNCTION Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs ### SEQUENCE -M-H-H-R-P-E-R-D-K-R-V-T-T-H-V-A-L-V-A-R-A-F-G-A-K-G-I-F-I-H-G-E-D-M-N-L-L-K-T-I-E-K-V-K-A-N-W-G-G-K-Y-F-S-I-E-F-V-K-N-P-K-K-V-V-R-D-W-R-N-S-G-G-I-V-V-H-L-T-M-Y-G-I-P-I-D-N-I-M-E-K-I-I-N-K-N-T-K-I-L-V-V-V-G-S-E-K-V-E-G-W-Y-Y-Y-N-S-D-Y-N-I-A-I-G-N-Q-P-H-S-E-V-A-A-L-A-I-F-L-D-R-I-Y-K-G-G-E-L-N-I-Q-F-S-D-A-K-L-S-I-I-P-Q-E-R-G-K-K-V-R-K-N-E"} +{"text": "### FUNCTION Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in Mjannaschii 16S rRNA It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3- ### SEQUENCE -M-K-V-Y-I-I-D-Y-H-R-D-D-P-K-K-C-T-G-R-K-L-I-K-L-N-F-A-E-L-T-R-Y-G-K-G-I-I-L-D-P-Y-S-K-R-I-L-S-I-L-D-K-D-I-A-L-K-T-G-I-T-I-V-D-T-S-W-N-S-T-S-K-I-E-F-E-K-I-K-G-E-H-R-R-L-P-I-L-F-A-G-N-P-T-N-Y-G-I-A-Y-K-L-S-S-I-E-A-V-I-A-S-L-Y-I-L-N-E-V-E-E-A-I-K-I-A-N-I-I-K-W-G-H-T-F-L-E-L-N-K-E-L-L-E-S-Y-R-N-K-S-E-N-E-I-L-E-I-E-R-E-V-I-E-K-I-I-G-E-P"} +{"text": "### FUNCTION Involved in protein export The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex ### SEQUENCE -M-P-S-S-K-K-K-K-E-T-V-P-L-A-S-M-A-G-L-I-R-Y-Y-E-E-E-N-E-K-I-K-I-S-P-K-L-L-I-I-I-S-I-I-M-V-A-G-V-I-V-A-S-I-L-I-P-P-P"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-A-G-G-K-S-P-K-G-M-F-A-A-R-K-L-R-L-K-R-L-K-F-R-W-H-Q-R-K-F-K-R-R-M-L-K-L-K-E-K-F-D-P-L-E-G-A-P-M-A-R-G-V-V-L-E-K-V-G-I-E-S-R-Q-P-N-S-A-V-R-K-A-V-R-V-Q-L-V-K-N-G-R-I-V-T-A-F-V-P-G-D-G-G-V-N-F-I-D-E-H-D-E-V-V-I-A-G-I-G-G-T-L-G-R-S-M-G-D-L-P-G-V-R-Y-K-V-I-M-V-N-G-V-S-L-D-A-L-Y-K-G-K-K-Q-K-P-V-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center ### SEQUENCE -M-E-S-F-E-V-S-S-I-D-L-K-V-F-G-K-W-D-T-K-V-E-I-R-D-P-S-L-K-K-Y-I-G-L-M-P-V-Y-L-P-H-T-G-G-R-H-E-H-R-R-F-G-K-A-K-L-P-I-V-E-R-L-I-N-N-V-M-R-P-G-R-N-K-G-K-K-M-L-A-Y-N-I-V-K-T-A-F-D-I-I-A-L-K-T-G-Q-N-P-I-Q-V-L-V-K-A-I-E-N-S-A-P-R-E-E-V-T-R-I-M-Y-G-G-I-V-Y-Y-V-A-V-D-V-A-P-Q-R-R-V-D-L-A-L-R-H-L-V-M-G-A-K-E-A-S-F-N-N-P-K-P-I-E-E-A-L-A-E-E-I-I-A-A-A-S-N-D-P-K-S-F-A-I-R-K-K-E-E-I-E-R-I-A-L-S-S-R"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-P-T-K-A-R-I-R-L-W-S-T-N-I-E-N-L-N-F-V-V-N-Q-I-K-T-L-A-Q-K-T-G-V-E-I-S-G-P-I-P-L-P-T-S-R-M-E-V-P-V-M-R-L-P-H-G-E-G-K-K-K-W-E-H-W-E-M-K-I-H-K-R-I-I-D-I-A-S-D-E-R-V-M-R-Q-L-M-R-V-R-V-P-D-D-V-Y-I-E-I-E-L-I"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-T-D-V-L-V-V-V-K-V-F-P-E-S-D-E-V-N-L-D-N-L-Y-E-E-I-G-K-K-L-P-A-G-Y-K-L-V-R-K-E-T-E-P-I-A-Y-G-L-K-A-L-I-A-Y-V-Q-M-P-E-N-V-E-G-G-T-D-T-L-E-E-I-I-N-S-I-Q-G-V-S-H-A-E-V-V-G-I-T-R-L-G-F"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-A-T-K-M-V-I-V-V-R-T-D-L-D-M-G-K-G-K-I-A-A-Q-V-A-H-A-A-V-S-L-V-L-D-I-L-N-S-S-N-S-L-W-K-E-W-L-Y-K-W-L-E-E-G-Q-P-K-I-V-V-K-V-P-S-L-D-E-L-N-K-R-Y-E-K-A-I-E-L-N-L-P-T-T-I-I-Q-D-A-G-K-T-Q-I-E-P-G-T-I-T-C-I-G-I-G-P-A-P-V-E-L-V-D-K-I-T-G-D-L-K-L-L"} +{"text": "### FUNCTION In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha-aminoadipate pathway ### SEQUENCE -M-A-D-V-D-E-S-D-L-K-I-L-E-I-L-R-K-N-A-R-T-P-Y-T-S-I-A-K-E-L-K-I-S-E-A-A-V-R-K-R-I-E-K-L-I-K-M-G-V-I-K-R-F-T-I-D-Y-E-L-E-N-E-I-R-A-I-V-M-V-K-T-N-P-Q-I-P-T-P-E-I-S-K-K-I-I-K-I-Q-G-V-E-F-V-Y-E-T-T-G-D-Y-D-I-L-T-V-V-R-G-T-N-I-S-S-I-N-K-T-I-D-D-I-R-S-L-Q-G-V-L-S-T-N-S-T-I-V-L-R-V-W-F"} +{"text": "### FUNCTION Broad-specificity nucleoside monophosphate kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-I-I-I-I-T-G-T-P-G-S-G-K-S-T-I-V-D-L-L-S-K-K-L-G-F-E-K-L-H-V-S-S-F-L-I-Q-N-K-A-F-S-E-Y-D-E-L-R-Q-S-Y-V-I-D-E-E-K-A-F-Q-L-I-D-S-F-I-K-D-K-N-V-V-I-E-T-I-Y-P-S-L-I-S-H-A-D-K-V-I-V-L-R-K-D-P-R-V-L-Y-T-E-L-K-R-R-G-W-G-E-L-K-I-A-E-N-V-M-A-E-I-L-G-V-I-S-G-E-A-K-E-Y-F-G-N-I-C-E-I-N-V-T-N-K-K-P-E-E-V-V-E-Q-I-L-S-N-N-C-D-N-V-D-W-L-N-I-E-E-I-Q-D-L-L-I-S-L-D-K-V-I-S-S-Y-E-D-S-I-S-D-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-L-M-D-P-L-A-N-A-L-N-H-I-S-N-C-E-G-V-G-K-S-V-A-Y-V-K-P-A-S-K-L-I-G-R-V-L-N-V-M-Q-D-H-G-Y-I-G-N-F-E-Y-I-E-D-G-R-A-G-I-Y-K-V-E-L-I-G-Q-I-N-K-C-G-A-V-K-P-R-Y-A-V-K-K-Q-E-F-E-K-F-E-K-R-Y-L-P-A-K-G-F-G-L-L-I-V-S-T-P-K-G-L-M-T-H-D-E-A-K-N-Q-G-L-G-G-R-L-I-S-Y-V-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-L-M-D-P-L-A-N-A-L-N-H-I-S-N-C-E-N-V-G-K-N-T-A-Y-L-K-P-A-S-K-L-I-G-R-V-L-K-V-M-Q-D-Q-G-Y-I-G-N-F-E-Y-I-E-D-G-K-A-G-V-Y-K-V-T-L-I-G-Q-I-N-K-C-G-A-V-K-P-R-F-A-V-K-N-Q-E-F-E-K-F-E-K-R-Y-L-P-A-K-G-F-G-L-L-I-V-S-T-P-K-G-L-M-T-H-D-E-A-K-D-S-G-I-G-G-R-L-I-S-Y-I-Y"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-L-M-D-P-L-A-N-A-L-N-H-L-T-N-C-E-R-V-G-K-K-V-F-Y-I-K-P-A-S-K-L-I-G-R-V-L-K-V-M-Q-D-H-G-Y-I-G-E-F-E-F-I-E-D-G-R-A-G-I-F-K-V-E-L-I-G-K-I-N-K-C-G-A-I-K-P-R-Y-A-V-K-K-H-E-F-E-K-F-E-K-R-Y-L-P-A-R-D-F-G-L-L-I-V-S-T-S-Q-G-I-M-T-H-Y-E-A-K-E-K-G-I-G-G-R-L-I-S-Y-V-Y"} +{"text": "### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-A-W-K-V-S-V-D-V-D-T-C-I-G-D-A-I-C-A-S-L-C-P-D-V-F-E-M-G-D-D-G-K-A-H-P-V-V-E-T-T-D-L-D-C-A-Q-E-A-A-E-A-C-P-V-G-A-I-T-L-E-E-A"} +{"text": "### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-I-D-F-D-G-N-M-I-N-I-S-R-K-D-V-V-A-R-K-A-T-A-V-G-R-I-Y-L-R-K-E-T-I-T-A-I-K-N-N-Q-V-K-K-G-N-V-I-E-I-S-R-A-V-G-T-M-Y-A-K-N-T-F-L-Q-I-P-Y-C-H-N-I-P-I-E-G-V-D-V-D-F-S-L-G-E-N-Y-V-E-V-T-C-S-T-T-T-S-Y-K-T-G-I-E-M-E-A-I-N-C-V-N-G-A-L-L-N-I-W-D-M-V-K-Y-L-E-K-D-E-T-G-N-Y-P-E-T-R-I-E-G-V-H-V-I-K-K-T-K-S-Q-E"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-S-E-R-E-K-I-T-I-E-N-I-V-A-S-T-S-L-A-E-H-L-D-L-S-R-I-A-L-A-L-D-G-S-E-Y-E-P-E-Q-F-P-G-L-I-Y-R-L-Q-D-P-K-T-A-V-L-I-F-R-S-G-K-V-N-C-T-G-A-K-N-I-E-D-V-K-R-T-I-K-I-I-I-D-K-L-K-A-A-N-I-E-V-Y-D-D-P-D-I-I-V-Q-N-I-V-A-V-Y-D-L-E-S-E-L-N-L-T-D-I-A-M-S-L-G-L-E-N-V-E-Y-E-P-E-Q-F-P-G-L-V-Y-R-V-E-E-P-R-V-V-L-L-L-F-G-S-G-K-V-V-C-T-G-A-K-E-E-S-E-I-E-Q-A-V-I-K-V-K-K-E-L-Q-K-V-G-L-I"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-V-E-P-N-I-S-S-Y-L-Q-N-Q-L-K-Q-A-Q-E-L-E-E-N-I-E-K-I-A-T-Q-R-Y-Q-L-D-L-S-L-K-E-I-E-K-T-L-Q-E-L-N-K-I-D-D-K-T-P-V-Y-R-S-I-G-S-I-L-Y-K-V-D-D-K-K-K-L-I-D-E-L-E-E-Q-L-E-L-T-K-I-R-I-N-T-L-D-K-Q-Q-K-S-L-E-E-K-Y-K-E-L-Q-A-A-I-R-E-R-Y-N-Q-D-N-K-K-G-A-V-S"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA to 40 S ribosomal subunits ### SEQUENCE -M-S-P-D-K-T-E-D-E-D-K-D-V-N-V-D-Q-D-Q-F-N-E-E-E-E-S-L-G-R-V-I-L-P-N-K-K-K-G-E-M-F-G-I-V-E-K-M-E-G-A-S-R-L-S-V-M-C-E-D-G-Y-T-R-N-A-R-I-P-G-R-M-R-K-R-M-W-I-R-E-K-D-L-V-I-V-K-P-W-E-F-Q-P-E-K-A-D-V-V-Y-R-Y-T-K-T-Q-A-S-Y-L-S-R-N-H-M-L-P-E-V-I-D-I-F-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-I-I-D-A-S-N-T-V-Y-G-R-L-S-A-Y-V-A-K-Q-L-L-N-G-E-E-V-V-I-V-N-A-S-K-A-V-I-T-G-D-R-K-F-I-I-D-K-F-K-Q-R-L-D-I-G-S-V-R-K-G-P-Y-Y-P-K-T-P-E-N-I-L-R-R-S-I-G-D-M-L-P-K-K-I-T-R-G-K-E-A-L-S-R-C-K-V-Y-R-N-L-P-K-N-V-S-S-E-K-I-E-K-V-D-D-V-M-T-D-K-V-V-G-I-I-T-L-E-E-L-S-K-E-L-G-G-M"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-A-E-E-N-I-I-F-V-G-K-K-P-T-M-N-Y-V-L-A-V-V-T-Q-F-N-N-N-A-N-K-I-I-I-K-A-R-G-K-T-I-S-K-A-V-D-V-A-E-I-T-R-H-K-F-I-P-D-A-K-Y-E-E-I-R-L-D-T-E-T-L-Q-G-E-R-G-S-S-N-V-S-S-I-E-I-T-L-S-R"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-S-Y-K-A-R-I-S-L-S-G-T-E-H-K-I-V-D-M-V-C-S-E-I-K-E-I-A-S-R-T-G-V-E-I-H-G-P-M-P-L-P-T-K-K-L-V-V-P-V-R-K-S-P-D-G-E-G-T-N-T-W-D-H-W-E-M-R-I-H-K-R-L-I-D-V-D-A-D-E-R-T-L-R-Q-L-M-R-I-P-I-P-D-G-V-Q-I-E-I-Q-I-K-S"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently ### SEQUENCE -M-T-Y-E-I-L-D-H-E-S-D-I-G-I-M-V-Y-G-T-T-Y-E-E-L-F-S-N-A-V-Y-A-M-A-D-L-I-L-D-V-G-K-L-K-E-K-R-K-M-H-E-I-I-R-G-N-T-P-E-D-I-M-V-N-L-L-S-R-V-L-F-Y-V-D-T-Y-Y-T-L-Y-F-R-A-T-C-K-Y-E-D-S-T-L-D-V-Y-L-Y-G-S-E-I-P-E-E-V-E-Y-R-N-V-I-K-A-V-T-Y-S-E-I-A-V-K-P-E-D-G-F-A-R-V-I-F-D-L"} +{"text": "### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-A-I-K-I-G-I-T-G-P-V-G-S-I-K-A-E-A-L-Q-K-I-I-G-M-L-Q-N-D-G-L-N-V-Q-G-V-L-I-S-K-V-S-D-D-G-K-L-T-G-Y-T-I-E-D-I-L-T-K-K-K-V-Q-F-C-D-E-K-F-V-S-R-V-K-I-D-K-L-G-V-D-T-R-L-L-E-E-I-L-I-P-S-L-Q-K-A-R-E-S-A-D-V-I-I-I-D-E-V-G-K-L-E-N-T-T-K-K-I-H-S-E-I-E-E-T-L-K-C-G-K-P-L-I-V-T-L-H-K-R-S-R-N-P-V-L-Q-E-I-K-S-L-E-G-V-R-V-F-D-I-T-P-I-N-K-N-I-L-P-F-K-V-M-H-V-L-K-G-E-E"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-E-E-K-T-L-K-I-S-K-I-K-D-G-T-V-I-D-H-I-P-S-G-K-A-L-R-V-L-S-I-L-G-I-R-D-D-V-D-Y-T-V-S-V-G-M-H-V-P-S-S-K-M-E-Y-K-D-V-I-K-I-E-N-R-S-L-D-K-N-E-L-D-M-I-S-L-T-A-P-N-A-T-I-S-I-I-K-N-Y-E-I-S-E-K-F-K-V-E-L-P-P-K-L-I-G-I-I-K-C-K-N-Q-N-C-I-T-N-T-R-E-P-V-K-P-E-F-E-I-V-S-R-H-P-L-V-L-R-C-V-Y-C-Q-R-T-M-N-E-R-D-V-F-E"} +{"text": "### FUNCTION Broad-specificity nucleoside monophosphate kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-G-K-I-A-C-I-T-G-P-P-G-A-G-K-S-T-V-C-S-K-L-R-E-Y-G-Y-N-C-K-E-G-N-E-L-A-K-E-Y-G-C-L-F-D-E-E-V-D-V-E-C-L-E-E-K-L-A-E-D-R-F-D-G-I-I-C-S-H-Y-S-H-L-L-G-C-S-T-V-F-I-L-E-A-D-L-N-D-L-I-D-R-M-R-A-R-G-Y-S-E-E-K-I-Q-E-N-I-E-T-Q-M-S-S-I-F-Y-Y-E-S-L-E-R-L-P-A-N-R-I-F-T-L-Y-N-G-N-I-D-E-T-A-K-R-I-I-S-I-I-E-R-S-R-N-N-K"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-A-D-V-L-V-S-F-K-L-L-P-S-D-S-D-V-D-T-S-V-M-E-S-E-V-K-E-K-L-N-G-V-C-K-I-N-N-I-E-E-K-D-I-G-F-G-L-K-Y-I-H-L-E-V-I-V-E-D-K-E-G-E-V-D-R-I-E-K-V-L-S-M-V-K-G-V-G-E-I-N-T-E-N-V-S-L-I"} +{"text": "### FUNCTION Located on the platform of the 30S subunit ### SEQUENCE -M-E-V-N-R-M-N-K-T-G-I-A-H-I-Y-A-S-Q-N-N-T-I-I-H-V-T-D-P-T-G-A-E-T-I-A-M-V-S-G-G-M-V-V-K-N-D-R-D-Q-A-S-P-Y-A-A-M-K-A-A-D-M-V-S-E-T-L-K-E-H-E-I-T-D-L-I-I-K-V-R-A-P-G-G-N-K-S-K-I-P-G-P-G-A-Q-A-A-I-R-A-L-S-R-A-G-L-K-I-V-R-I-E-E-V-T-P-I-P-H-D-G-T-K-K-K-G-G-K-R-G-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-G-K-A-S-A-N-N-V-K-S-D-K-E-A-A-K-P-A-A-K-K-D-E-N-K-D-F-Q-Y-I-V-R-I-A-N-K-D-L-N-G-E-R-P-I-P-L-A-L-S-D-L-K-G-I-G-L-R-L-G-Y-A-I-A-E-R-L-N-L-Q-P-T-K-K-I-G-E-L-K-E-D-E-I-E-K-L-K-E-Y-V-E-N-K-E-Y-D-L-P-D-W-L-L-N-H-R-R-E-P-V-T-G-K-N-L-N-L-V-T-T-D-L-D-V-Q-V-Q-E-D-I-N-L-M-K-K-I-R-S-Y-K-G-I-R-H-E-K-G-K-K-V-R-G-Q-R-T-R-S-N-G-R-R-G-L-S-I-G-V-V-R-K-K-E"} +{"text": "### FUNCTION Functions by promoting the formation of the first peptide bond ### SEQUENCE -M-S-W-Q-E-A-E-V-R-E-L-K-V-G-R-Y-I-L-I-D-D-V-P-C-K-I-V-E-I-T-M-S-K-P-G-K-H-G-E-A-K-G-R-I-V-A-I-G-V-F-D-N-Q-K-R-S-V-V-Y-P-V-K-H-K-V-K-I-P-I-I-E-K-K-N-A-Q-V-L-S-V-M-N-N-E-A-Q-L-M-D-S-E-T-F-E-T-F-V-L-P-L-D-P-E-I-A-D-K-V-K-P-G-M-E-V-P-Y-W-E-A-M-G-V-R-K-I-M-L-Q-N"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-A-R-D-V-E-A-Q-L-N-Y-I-E-S-L-I-S-S-V-D-A-Q-I-D-A-I-N-K-M-V-L-E-V-Q-T-T-I-Q-I-L-S-S-D-E-L-R-Q-S-K-E-R-L-I-S-V-G-S-G-I-F-A-N-G-N-L-D-L-D-S-D-L-I-V-P-I-G-S-G-V-Y-I-A-E-K-R-S-E-T-I-E-R-L-K-A-N-I-E-N-L-K-E-S-I-Q-K-L-M-D-Q-R-R-T-L-V-D-Q-Y-N-T-V-Y-T-T-E-A-T-R-N-I-K"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-Y-S-P-S-S-S-N-Y-I-K-D-P-I-S-T-E-I-I-K-S-K-T-R-N-L-K-K-R-A-E-E-A-I-L-Y-R-S-I-A-E-Q-S-S-R-K-L-A-E-I-S-E-A-Y-K-H-K-L-A-D-M-E-N-Y-L-K-I-K-D-R-E-T-E-I-I-R-K-N-A-N-E-S-L-I-K-D-F-L-P-V-I-D-S-M-D-A-A-I-Q-A-E-K-D-N-N-L-I-R-I-R-D-Q-M-L-S-I-L-S-K-Y-G-L-Q-P-I-K-A-E-G-E-K-F-D-P-Y-L-H-E-A-I-G-M-T-Q-D-G-E-D-G-K-I-K-Y-E-V-Q-R-G-Y-T-L-N-N-S-V-L-R-T-S-K-V-I-V-V-K-R"} +{"text": "### FUNCTION Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A ### SEQUENCE -M-L-L-R-S-G-S-K-Y-I-I-T-A-E-A-R-E-E-I-K-K-R-N-G-K-L-V-T-I-D-E-M-V-E-V-S-K-S-T-Q-L-D-S-V-G-D-V-T-T-T-N-L-R-R-A-G-A-K-L-F-L-Q-I-V-D-L-K-T-K-R-G-E-S-I-F-Q-H-E-E-G-S-I-T-V-R-N-D-P-G-T-I-S-F-D-L-I-E-A-I-K-S-S-I-E-N-N-K-P-T-R-I-E-V-I-G-E-E-D-L-A-V-L-P-I-I-Y-Y-S-K-N-N-T-V-I-A-Y-G-I-P-D-V-G-M-A-A-L-T-V-T-D-D-L-R-D-H-V-T-E-V-I-A-K-M-A-I-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-Q-S-V-K-T-M-V-E-G-G-K-A-T-T-G-P-P-I-G-P-A-L-G-P-L-G-L-N-V-A-Q-V-V-K-E-I-N-E-K-T-K-E-F-Q-G-M-Q-V-P-V-T-V-T-V-I-D-P-E-T-K-K-Y-E-I-T-V-G-V-P-P-T-S-A-L-L-K-K-E-L-G-L-E-K-G-A-S-K-K-K-E-A-V-A-G-N-A-T-L-E-Q-I-K-N-V-A-I-K-K-M-P-S-M-L-A-K-D-L-K-S-A-V-L-E-V-L-G-T-C-V-A-M-G-I-N-V-E-G-K-D-P-K-E-V-Q-K-L-I-K-S-G-Q-I-K-I-E-Q"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-S-N-G-T-A-V-M-G-K-I-N-N-K-K-T-H-I-T-C-R-R-C-G-H-H-T-Y-N-V-R-T-K-R-C-S-H-C-G-F-P-A-P-R-I-R-S-Y-K-W-A-K-A-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-V-R-E-R-T-K-K-L-R-G-G-H-Y-G-R-G-M-K-A-G-R-G-K-G-K-K-G-G-R-G-N-A-G-M-G-K-H-K-W-I-W-M-V-K-Y-D-P-L-H-F-G-G-K-G-F-T-S-H-H-L-S-T-P-D-V-P-I-N-L-G-E-L-E-N-I-F-E-N-L-K-A-D-G-F-V-R-E-E-N-G-E-T-V-V-D-L-K-A-A-G-Y-D-K-L-L-G-S-G-N-F-S-V-K-S-R-I-I-I-D-K-A-T-E-K-A-I-S-K-L-S-A-I-G-S-K-I-E-N-V-G-N-T-A-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-F-K-R-K-V-L-G-K-T-D-Y-G-R-R-L-R-L-L-K-S-K-D-R-R-F-I-V-R-I-T-N-K-G-I-I-A-Q-I-A-E-Y-S-V-N-G-D-R-I-L-A-T-I-T-D-K-A-L-S-K-Y-G-I-E-L-R-G-N-N-L-Q-I-C-Y-L-V-G-Y-A-A-G-V-E-A-Q-K-A-G-V-E-T-A-V-L-D-I-G-R-K-K-F-R-K-G-G-R-I-A-A-C-L-K-G-I-T-D-S-G-V-D-I-P-H-G-E-D-V-F-P-D-K-K-R-L-N-G-S-H-L-K-N-P-V-K-L-N-E-A-V-K-N-F-K-K-L-E-E-K-A"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-I-K-W-E-E-A-S-V-I-E-I-P-K-D-V-K-V-G-L-S-G-T-M-L-S-M-T-F-G-N-K-K-L-E-K-K-F-A-D-N-Y-V-R-L-L-V-E-D-N-K-I-K-I-V-K-S-K-N-N-S-R-E-R-G-I-V-G-T-W-A-S-E-I-S-N-M-V-K-G-L-K-E-G-F-Q-Y-E-M-K-I-D-Y-S-H-F-P-M-R-V-S-V-K-G-K-T-V-V-I-E-N-F-F-G-E-R-S-P-R-T-A-E-I-V-G-E-T-Q-V-S-V-K-G-D-R-L-F-L-N-G-P-S-K-K-D-V-G-E-T-A-A-N-I-E-R-A-T-I-I-K-G-F-D-P-R-V-F-Q-D-G-I-Y-L-I-S-K-G-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-R-N-D-T-L-N-D-V-I-N-S-I-K-N-A-S-R-L-G-R-R-E-I-I-A-E-P-A-A-K-L-I-G-K-V-L-K-V-M-Q-D-Y-N-Y-I-K-S-F-E-V-I-D-E-S-R-G-G-K-F-K-I-V-L-N-T-T-I-N-N-C-G-V-I-K-P-R-F-P-V-K-N-E-N-L-E-K-Y-E-S-R-Y-L-P-A-E-D-F-G-I-L-I-L-T-T-T-K-G-V-M-S-N-I-E-A-R-K-L-G-I-G-G-K-L-L-A-Y-V-Y"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-S-Q-V-K-L-Q-P-K-K-K-Y-G-H-I-D-G-C-V-R-C-G-R-K-R-G-I-V-R-K-Y-G-L-H-L-C-R-Q-C-F-R-E-T-A-R-Q-L-G-F-E-K-Y-S"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-Q-M-Q-E-I-I-I-D-K-V-V-V-N-I-G-V-G-Q-A-G-D-R-L-T-K-A-A-K-V-L-E-M-L-T-G-H-K-P-T-Q-T-L-A-K-K-S-V-R-D-F-N-I-R-K-R-L-P-I-G-V-K-V-T-L-R-K-D-D-A-V-N-F-L-N-K-A-L-Y-V-K-D-Y-K-I-P-D-Y-S-F-D-K-H-G-N-A-Y-F-G-I-S-D-Y-T-D-F-K-G-M-K-Y-D-P-D-I-G-I-F-G-M-D-V-A-I-V-L-K-R-R-G-G-Y-R-I-E-K-R-K-I-G-K-K-T-I-P-S-S-I-R-I-K-K-D-E-A-V-E-F-L-E-K-N-F-K-V-S-V-V-R"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Y-D-K-L-N-V-A-L-S-K-D-L-R-K-K-Y-G-I-R-S-F-P-I-V-K-G-D-V-V-K-V-V-S-G-A-R-K-G-E-G-G-K-V-A-E-V-D-H-H-S-G-L-V-I-V-E-G-I-T-I-A-K-I-D-G-K-Q-K-G-F-G-I-S-P-E-K-L-Q-I-T-H-L-D-L-S-R-S-E-R-F-Q-K-I-K-E-L-A-N-I-K-H-I-T-I-Q-E-E-P-I-Q-E-E-Q-Q-K-T-E-E-T-K-Q-E-I-A-P-E-E-V-E-A-K-E-A-Q-D-K-Q-E-V-K-E-N-D-Q"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-K-G-I-A-G-R-E-I-R-G-L-P-L-G-A-N-I-V-C-A-D-N-T-G-A-R-S-I-S-L-I-D-V-K-A-Y-H-G-K-A-R-R-I-P-A-A-G-V-G-D-M-F-I-A-S-V-K-K-G-T-P-E-M-R-S-K-V-V-Y-A-V-V-I-R-Q-K-R-P-Y-R-R-P-D-G-T-M-V-E-F-E-D-N-A-A-V-L-V-T-P-D-G-E-V-R-G-S-E-I-K-G-P-V-A-R-E-A-A-E-R-W-P-R-I-A-A-I-A-S-I-I-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-Q-A-R-N-I-G-L-D-V-S-V-P-E-K-E-C-T-D-P-H-C-P-F-H-G-N-L-P-V-R-G-Q-V-L-T-G-K-V-I-S-T-A-M-T-R-S-V-V-V-A-R-E-Y-Q-Q-Y-I-P-K-Y-E-R-K-A-T-K-I-K-K-Y-H-V-H-V-P-D-C-I-E-L-R-V-G-D-T-V-R-F-A-E-C-R-K-L-A-K-T-I-S-F-V-V-V-E-K-V-K-Q"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-I-Y-I-S-E-F-I-G-R-H-V-E-V-I-Q-S-S-N-R-Y-D-V-G-I-S-G-Q-V-S-F-E-T-K-N-T-F-E-I-T-K-G-T-G-K-V-I-V-P-K-E-G-R-I-F-T-F-D-G-K-F-K-V-D-G-S-L-I-N-Y-R-P-E-D-R-L-R-E-Y-R-K-I-L-K-K-L-G-G-N"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-K-G-Y-S-M-S-V-D-E-N-N-A-R-A-R-I-V-E-A-D-I-S-L-K-D-A-V-N-I-A-H-H-I-R-G-M-K-L-D-Y-A-K-Q-I-L-E-D-V-V-S-K-K-Y-A-I-P-Y-F-R-Y-L-D-S-V-S-H-R-P-G-K-G-P-G-R-Y-P-V-K-A-A-K-V-F-I-D-L-L-S-N-V-E-N-N-A-E-F-K-G-M-N-T-D-S-L-I-I-K-H-V-A-A-N-K-G-R-M-I-K-K-Y-T-P-K-A-Y-G-R-A-G-A-N-F-K-D-L-I-N-L-E-V-I-V-T-E-G-D-Q"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-V-V-N-K-Q-G-S-V-K-S-I-K-R-K-A-R-K-S-R-K-V-T-T-G-R-A-K-E-F-S-Y-K-G-Y-T-L-E-Q-L-Q-E-M-S-L-E-E-L-I-K-I-L-P-A-R-A-R-R-S-L-S-R-E-M-N-H-D-Q-K-K-L-V-E-K-L-E-G-D-Y-D-D-I-K-T-H-V-R-D-V-I-I-L-P-S-Y-V-G-K-I-V-E-V-Y-N-G-N-S-Y-S-K-F-E-I-K-P-E-M-I-G-H-Y-L-G-E-F-V-M-T-R-K-E-V-K-H-S-G-P-G-V-G-A-T-R-S-S-K-F-M-P-L-K"} +{"text": "### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-G-D-V-I-L-S-P-V-S-T-E-K-T-A-L-L-A-E-K-E-N-K-L-T-L-I-V-D-R-K-A-T-K-E-D-I-K-R-E-V-E-S-R-F-S-V-K-V-E-G-I-N-I-L-I-T-K-K-G-K-K-A-I-V-K-L-A-K-E-Y-S-A-E-E-I-A-E-R-I-G-V-F"} +{"text": "### FUNCTION Involved in protein export The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex ### SEQUENCE -M-A-S-D-K-K-S-E-G-F-Q-S-G-A-G-L-I-R-Y-F-E-E-E-E-I-K-G-P-A-L-D-P-K-L-V-V-Y-I-G-I-A-V-A-I-M-V-E-L-A-K-I-F-W-P-P"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-T-N-V-P-D-G-L-K-Y-T-K-T-H-E-W-Y-K-V-D-N-G-I-A-T-V-G-I-T-D-Y-A-Q-S-Q-M-T-D-I-V-Y-V-D-L-P-E-V-G-D-K-K-K-V-G-D-V-L-L-T-I-E-S-V-K-S-A-E-D-V-Y-S-P-L-T-G-E-I-T-E-V-N-Q-E-L-T-K-H-P-E-N-I-N-K-D-P-Y-G-N-W-L-V-K-M-K-V-E-K-E-G-E-Y-L-T-A-E-Q-Y-R-K-L-I-Q"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-V-K-L-V-V-A-V-R-K-D-L-D-M-G-K-G-K-I-A-A-Q-V-A-H-A-A-V-S-C-A-I-K-A-M-K-E-K-K-K-I-F-D-E-W-M-D-E-G-Q-K-K-I-V-V-K-V-P-N-V-D-E-I-Y-I-I-K-K-K-A-D-S-M-G-I-I-N-E-V-I-Q-D-R-G-Y-T-Q-V-E-P-G-T-V-T-C-I-G-L-G-P-D-Y-E-V-Y-L-D-D-I-T-G-K-Y-K-L-L"} +{"text": "### FUNCTION Catalyzes the formation of CDP-2,3-bis- and CTP This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-N-Y-P-L-L-M-A-Q-A-I-I-L-F-V-P-A-L-I-A-N-S-G-A-V-L-T-G-G-Y-F-V-L-D-R-G-K-N-F-I-D-G-R-R-I-L-G-D-G-K-T-L-S-G-Y-L-G-G-S-F-I-G-I-V-S-G-V-I-I-Y-W-I-S-Y-A-T-H-F-I-L-G-N-Y-G-S-I-A-L-S-I-E-I-P-A-V-M-A-F-G-S-L-T-G-D-I-L-G-S-F-V-K-R-R-I-G-I-K-S-G-G-K-G-G-L-L-D-Q-W-P-F-A-L-V-A-F-L-F-L-F-L-M-E-R-P-F-F-L-H-Y-Y-F-F-A-G-I-I-V-I-L-A-I-V-P-P-L-H-R-A-V-N-I-I-G-Y-K-L-H-K-K-D-V-P-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-G-N-G-L-N-A-G-R-K-L-L-E-N-R-K-K-F-R-W-S-D-R-D-Y-K-R-R-V-L-Q-L-K-R-K-S-D-P-L-E-G-A-P-Q-A-K-G-I-A-I-E-K-V-G-I-E-A-K-Q-P-N-S-A-I-R-K-C-V-K-V-Q-L-I-K-N-G-R-Q-I-T-A-F-A-V-G-D-G-A-I-N-Y-I-D-E-H-D-E-V-T-V-E-G-I-G-G-R-M-G-R-S-K-G-D-I-P-G-V-R-Y-K-V-V-A-V-N-G-I-S-L-K-E-L-V-K-G-R-K-E-K-T-V-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center ### SEQUENCE -M-L-F-D-K-Y-D-V-N-S-V-E-V-H-D-P-G-M-V-K-Y-I-N-V-K-S-A-L-N-L-H-T-G-G-R-F-S-S-Y-Y-A-G-K-I-N-M-N-V-V-E-R-L-I-N-K-L-M-R-T-E-K-W-T-G-K-K-Y-S-A-Y-K-I-T-K-D-A-F-D-I-I-A-D-K-T-K-Q-N-P-L-Q-I-L-I-N-A-I-E-N-A-G-P-R-E-E-V-T-R-L-K-Y-G-G-I-A-V-P-K-S-V-D-V-S-P-S-R-R-V-D-E-A-L-R-N-I-A-T-G-A-T-N-A-S-F-K-S-K-K-S-I-V-N-C-L-A-D-E-I-M-L-A-A-K-N-D-A-S-S-F-A-I-S-K-K-E-E-I-E-R-V-A-Q-S-A-R"} +{"text": "### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-I-P-G-R-M-N-S-R-E-M-R-R-L-M-A-Q-M-G-I-K-S-T-E-M-D-D-V-K-K-V-I-F-V-G-K-E-K-D-Y-V-I-E-N-A-Q-V-T-M-I-E-A-Q-G-V-K-T-F-Q-V-V-G-D-F-R-E-T-P-K-K-Q-E-G-K-K-E-E-T-F-P-E-D-D-I-K-L-V-M-D-Q-T-G-V-A-R-E-K-A-I-E-A-L-K-A-A-S-G-E-P-A-Q-A-I-L-N-L-T-Q-K"} +{"text": "### FUNCTION Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in Mjannaschii 16S rRNA It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3- ### SEQUENCE -M-T-G-I-Y-Y-L-Y-L-R-Q-D-D-P-K-K-A-T-M-R-K-L-E-R-F-G-L-A-K-R-V-D-I-K-G-V-G-L-K-L-V-L-T-P-Y-A-D-I-F-L-S-R-E-D-A-V-L-Y-E-K-Y-G-L-C-V-I-E-G-S-W-N-K-I-D-S-I-K-S-L-K-F-R-I-E-R-R-L-P-A-L-L-A-A-N-P-V-N-Y-G-K-I-G-I-L-S-S-V-E-A-T-A-A-A-L-Y-I-I-G-Y-W-D-T-A-Y-A-L-L-S-K-F-S-W-G-L-N-F-I-K-L-N-E-N-P-L-N-E-Y-S-T-A-D-R-S-E-I-K-K-I-E-E-S-Y-F-G"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-Q-S-C-I-T-V-I-G-E-R-D-V-V-L-G-F-R-L-L-G-I-T-N-T-I-V-A-E-G-K-D-L-V-K-K-F-M-E-E-F-E-N-P-H-C-S-V-I-V-V-S-E-H-L-K-N-M-I-D-K-K-T-L-R-S-I-E-V-S-S-K-P-L-V-V-F-I-P-L-P-G-F-K-E-E-E-S-I-E-T-M-A-K-R-I-L-G-I-D-I-G-S-V"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-L-E-Q-V-I-K-E-I-E-Q-S-Q-E-I-K-K-K-E-I-L-E-N-T-K-N-I-L-D-K-M-E-A-E-K-K-A-K-I-D-E-I-R-A-L-Y-Q-E-K-M-R-A-E-S-S-R-I-T-A-S-I-I-D-K-A-N-I-E-A-R-S-I-L-R-N-K-I-E-E-I-L-E-G-Y-V-S-A-A-Q-E-I-L-R-N-I-R-N-M-P-E-Y-P-A-L-L-N-K-M-I-E-V-A-K-K-Y-L-G-Q-D-C-I-I-K-V-D-S-K-D-K-A-V-A-P-S-S-G-I-T-Y-S-N-I-D-P-Y-G-G-I-L-A-S-S-R-D-G-K-V-E-L-D-L-R-V-S-S-I-M-E-E-V-L-E-K-I-K-V-K-I-Y-T-R-L-E-E"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-L-S-E-D-L-V-K-S-G-A-I-K-F-G-D-F-I-L-T-S-G-K-R-S-D-Y-Y-V-D-I-K-E-A-A-T-D-P-N-L-L-S-E-I-A-S-E-F-S-K-M-I-H-A-R-K-I-A-G-M-E-L-G-A-V-P-L-I-V-A-T-S-L-N-M-G-I-P-Y-V-I-V-R-K-E-R-S-H-G-T-L-S-L-I-V-G-R-L-N-R-G-E-E-V-D-V-I-E-D-V-V-T-T-G-N-S-V-L-K-A-I-N-V-L-R-E-N-G-V-V-V-K-D-A-Y-C-V-V-D-R-E-E-G-G-A-K-L-L-E-N-N-G-I-K-L-H-P-I-V-R-I-S-E-L-K-R"} +{"text": "### FUNCTION May be involved in maturation of the 30S ribosomal subunit ### SEQUENCE -M-V-S-V-K-Y-V-P-S-D-M-L-I-N-Y-V-S-G-K-L-K-E-E-K-K-I-K-E-P-N-W-V-K-F-V-K-T-G-V-S-K-E-K-P-P-L-Q-D-D-W-I-Y-V-R-A-A-S-M-L-R-K-L-Y-I-N-G-Y-L-G-I-S-R-M-S-S-E-Y-G-G-K-V-D-R-G-S-K-R-Y-H-A-A-S-G-S-R-S-I-T-R-F-L-F-H-E-L-E-S-A-G-L-V-Q-K-T-Q-K-G-R-S-L-S-P-Q-G-M-S-L-L-D-N-A-S-K-E-I-I-K-Q-L-A-Q-K-D-P-L-Y-E-K-F-I"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-E-N-R-I-R-K-N-A-E-F-R-R-V-Y-R-K-G-K-S-F-S-N-R-L-L-V-L-Y-V-Y-K-N-Y-I-L-K-D-I-N-R-I-G-I-S-V-S-K-K-V-G-K-S-V-V-R-S-R-V-K-R-L-I-G-E-S-Y-R-L-N-S-S-N-L-K-K-G-H-D-F-V-I-I-A-R-T-A-C-N-G-K-R-Y-S-D-I-E-D-S-I-K-N-L-F-N-K-A-G-L-V-I-Y-D-E-K-N-I-T"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-N-K-Y-E-T-L-F-I-L-N-P-S-L-D-E-E-G-I-N-T-N-V-E-K-F-K-S-V-I-T-N-G-G-G-E-V-E-N-V-D-L-W-G-K-R-K-L-A-Y-E-I-D-K-V-N-E-G-I-Y-V-L-V-N-F-Q-S-D-A-Q-L-P-K-E-L-D-R-V-F-R-I-S-D-S-I-I-R-H-L-I-I-S-L-E-K"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-D-N-G-N-K-D-R-D-G-K-R-P-N-G-G-R-N-R-K-M-K-R-K-I-C-S-F-C-M-E-K-S-E-S-I-D-Y-K-D-I-N-K-L-R-K-Y-V-T-E-R-G-K-I-L-P-R-R-I-S-G-N-C-A-K-H-Q-R-E-L-T-I-A-I-K-R-A-R-N-I-A-L-L-P-F-T-T-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-L-K-D-I-K-S-V-G-K-K-G-E-V-I-N-V-S-D-G-Y-A-R-N-F-L-F-P-R-K-L-A-E-E-A-N-N-S-N-M-R-V-L-N-L-K-K-D-A-E-R-K-Q-K-L-Q-E-T-E-E-A-Q-K-L-A-N-E-L-K-G-K-V-L-K-L-S-A-K-A-G-E-N-G-R-L-F-G-A-I-T-S-K-D-I-A-A-E-I-K-K-Q-F-N-V-D-I-D-K-K-K-V-N-S-E-T-I-R-K-L-G-N-Y-E-I-E-L-K-L-Y-P-E-I-S-T-K-I-N-V-L-I-S-E-G"} +{"text": "### FUNCTION Probably involved in tryptophan uptake ### SEQUENCE -M-R-M-N-L-K-K-L-I-I-N-S-L-F-L-A-V-G-V-V-L-N-Q-I-T-P-P-I-L-F-G-M-K-P-D-F-S-L-A-M-L-F-I-I-I-L-L-N-D-D-Y-K-T-C-I-S-T-G-V-V-A-G-L-L-A-A-A-V-T-T-F-P-G-G-Q-L-P-N-I-I-D-R-I-V-T-T-S-L-V-F-I-A-L-R-P-F-K-D-K-I-N-D-K-I-H-M-I-I-T-T-I-V-G-T-I-I-S-G-S-V-F-L-G-S-A-L-I-I-V-G-L-P-A-S-F-K-A-L-F-I-T-V-V-L-P-A-T-I-I-N-A-I-V-G-T-I-I-F-V-A-V-K-K-S-M-R-V-V-F-R-Q"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-N-I-T-L-I-T-V-G-K-L-K-E-K-Y-L-K-D-A-V-N-E-Y-A-K-R-L-Q-K-Y-C-K-L-N-I-I-E-L-Q-D-E-K-T-P-E-K-A-S-L-K-E-E-K-L-I-K-E-K-E-G-E-K-I-L-S-S-I-K-D-N-S-Y-V-V-S-M-D-L-K-G-K-M-F-S-S-E-E-F-S-A-F-I-D-D-L-G-V-R-G-N-S-S-I-D-F-V-I-G-G-S-L-G-L-S-D-A-V-L-A-R-A-N-Y-K-L-C-F-S-K-M-T-F-P-H-Q-L-F-R-V-M-L-L-E-Q-V-Y-R-A-F-R-I-S-R-G-E-P-Y-H-K"} +{"text": "### FUNCTION Catalyzes the dephosphorylation of nucleotide monophosphates and of different sugar phosphates in vitro ### SEQUENCE -M-E-Q-L-N-I-C-I-D-I-D-G-T-I-T-D-A-Y-Y-W-I-D-L-C-N-S-Y-F-K-T-S-I-T-E-K-D-A-T-Q-Y-Y-I-H-K-I-L-N-V-P-L-E-E-Y-N-E-F-Y-E-K-Y-K-Y-K-L-H-S-E-Q-K-L-R-K-D-V-K-S-V-I-T-K-L-S-Q-N-N-N-I-F-F-V-T-A-R-E-R-D-L-T-I-L-T-Y-S-Y-L-R-K-K-E-I-P-Y-D-S-L-F-I-L-G-T-H-H-K-V-P-T-A-R-Q-L-N-C-D-L-F-I-E-D-N-Y-D-N-A-L-E-L-S-K-A-G-F-K-V-L-L-I-D-T-Y-Y-N-R-K-P-L-N-Q-N-I-I-R-F-Y-N-W-D-E-V-Y-G-I-V-D-R-L-F-E-K-S-E-A-I"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-I-R-K-I-T-S-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-F-K-D-I-A-H-P-I-N-T-A-T-R-E-K-I-Q-S-A-I-L-A-E-Y-E-K-V-K-N-E-E-E-T-K-T-E-T-E-E"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-F-L-I-V-G-L-G-N-P-G-L-K-Y-E-H-T-R-H-N-M-G-F-D-A-I-E-N-I-A-A-K-H-N-I-S-I-D-K-K-G-F-K-G-L-Y-G-K-G-I-I-D-G-E-K-V-I-L-L-K-P-Y-T-Y-M-N-L-S-G-E-S-V-V-E-A-A-N-Y-Y-K-I-N-K-E-N-I-V-V-I-Y-D-D-I-S-L-D-V-G-K-I-R-I-R-T-K-G-S-A-G-G-H-N-G-I-K-N-I-V-L-H-L-S-S-E-E-F-P-R-V-K-V-G-V-G-E-P-T-E-N-L-V-N-Y-V-L-G-K-F-S-Q-D-E-R-K-K-I-E-E-V-L-N-I-V-T-E-A-V-E-C-M-V-V-D-G-V-Q-N-A-M-N-K-F-N-G-L-K-L"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-Q-E-K-K-Y-V-I-T-Y-K-G-V-K-K-L-E-E-E-L-E-Y-L-K-T-T-K-R-K-E-I-T-E-K-I-K-V-A-L-S-F-G-D-L-S-E-N-S-E-Y-D-E-A-K-N-D-Q-A-F-V-E-G-R-I-A-Q-I-E-N-M-L-K-N-A-N-V-I-D-E-S-E-L-K-N-D-V-V-S-V-G-S-K-V-M-V-K-D-Y-Q-F-D-E-E-I-E-F-S-I-V-G-S-A-E-A-D-P-I-E-N-K-I-S-N-E-S-P-V-G-S-A-L-I-G-K-K-V-G-D-E-I-E-V-N-V-P-D-G-V-D-K-Y-K-I-L-A-I-K"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-K-V-N-G-D-V-L-K-Y-G-D-N-I-D-T-D-V-I-I-P-A-R-Y-L-N-T-S-V-P-E-E-L-A-K-H-C-M-E-D-L-D-V-D-F-L-K-K-L-K-T-G-D-I-V-V-G-G-R-N-F-G-C-G-S-S-R-E-H-A-P-I-C-I-K-A-A-G-V-S-C-V-I-A-K-S-F-A-R-I-F-Y-R-N-S-I-N-I-G-F-P-I-L-E-C-E-E-A-V-N-D-A-S-T-G-D-K-L-E-V-D-F-I-E-G-I-I-K-N-V-T-L-N-K-E-Y-K-A-Q-P-F-P-D-F-M-L-K-I-M-K-N-E-G-L-T-N-C-V-K-K-G-L-F"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-V-G-L-I-K-L-Q-L-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-A-F-C-K-E-Y-N-A-K-T-A-N-Q-A-G-F-T-I-P-V-V-I-T-V-Y-Q-D-R-S-F-S-F-I-L-K-T-P-P-A-A-V-L-I-K-K-A-A-G-I-E-S-G-S-G-V-P-N-K-N-K-V-G-K-I-T-K-E-Q-V-K-E-I-A-Q-T-K-M-P-D-L-N-A-A-S-L-E-A-A-M-S-M-I-A-G-T-A-R-S-M-G-V-E-V-V-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-V-N-K-N-R-Q-L-K-E-Q-K-V-A-E-I-K-E-K-M-G-K-T-E-A-M-I-M-V-K-Y-Q-G-L-N-V-E-E-D-T-E-L-R-K-A-L-R-E-A-G-V-E-Y-R-V-Y-K-N-S-L-A-V-R-A-I-N-E-L-G-Y-E-G-I-A-Q-Y-L-E-G-P-I-A-I-A-M-S-Y-D-D-P-T-A-P-A-R-I-I-N-D-F-A-K-T-H-K-A-L-E-L-V-A-G-Y-V-Q-G-E-V-F-D-V-N-K-V-K-E-L-A-S-V-P-A-K-E-V-L-I-A-K-L-L-G-S-F-K-A-P-L-S-N-F-A-Y-L-L-S-A-I-K-D-K-K-E-A-E-E-Q-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-T-R-E-E-I-I-E-A-I-K-G-M-S-V-L-E-L-N-E-L-V-K-A-C-E-E-E-F-G-V-S-A-A-A-P-V-A-V-A-G-A-A-G-A-A-G-A-A-A-G-E-E-K-T-E-F-D-V-V-L-A-E-A-G-A-K-K-L-Q-V-I-K-V-V-R-E-L-T-G-L-G-L-K-D-A-K-A-L-V-D-G-A-P-K-T-I-K-E-G-V-A-K-E-E-A-E-S-M-K-A-K-I-E-E-A-G-G-K-V-E-L-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-S-Q-L-V-R-K-G-R-K-T-L-A-A-K-S-T-A-P-A-L-K-E-C-P-Q-K-R-G-V-C-T-V-V-K-T-T-T-P-K-K-P-N-S-A-L-R-K-I-A-R-V-R-L-T-N-G-Y-E-V-T-A-Y-I-P-G-V-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-A-A-G-V-A-D-R-K-Q-A-R-S-K-Y-G-A-K-K-P-K-Q-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-H-I-A-K-R-D-V-L-P-D-P-L-Y-N-S-K-V-V-T-K-L-I-N-N-I-M-E-D-G-K-K-G-V-A-Q-K-I-C-Y-N-A-F-E-Y-L-K-E-K-T-G-K-E-P-M-E-V-F-E-A-A-M-N-N-V-M-P-L-L-E-V-K-A-R-R-I-G-G-A-T-Y-Q-V-P-I-E-V-R-P-E-R-R-Q-T-L-G-I-R-W-M-L-A-A-A-D-K-R-G-E-K-Y-M-H-L-K-L-A-G-E-L-L-D-A-S-N-N-T-G-A-A-V-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-Y"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-K-Q-K-I-R-I-R-L-K-A-F-D-H-T-I-L-D-Q-S-A-E-K-I-V-E-T-A-K-T-T-G-A-K-V-A-G-P-V-P-L-P-T-E-K-D-V-V-T-I-L-R-S-P-H-K-Y-K-D-S-R-E-Q-F-E-I-R-T-H-K-R-L-I-D-I-I-S-P-S-P-K-T-V-D-A-L-M-R-L-D-L-P-A-G-V-D-I-E-I-K-L"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-Y-T-N-S-H-D-I-I-R-K-P-V-I-T-E-K-S-M-A-E-M-A-D-K-K-Y-T-F-I-V-D-P-H-A-N-K-V-Q-I-K-K-A-I-E-E-V-F-G-V-K-V-E-K-V-N-T-S-N-I-L-G-K-T-K-R-V-G-V-H-V-G-K-R-A-D-Y-K-K-A-I-V-K-L-T-E-D-S-K-A-I-E-F-F-E-G-M-Q"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-I-K-K-G-P-F-V-K-E-S-L-L-N-K-I-V-E-M-N-K-A-G-D-K-K-V-V-K-T-W-S-R-S-S-T-I-F-P-E-M-I-G-H-T-I-A-V-H-D-G-R-K-H-V-P-V-Y-I-S-E-D-M-V-G-H-K-L-G-E-F-V-L-T-R-T-F-R-G-H-G-N-T-E-K-T-T-S-V-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-I-A-K-Y-V-R-M-S-P-M-K-V-K-I-V-L-D-L-I-R-G-K-N-V-N-E-A-F-A-I-L-Q-Y-T-P-K-D-A-A-V-V-I-N-K-V-L-K-S-A-V-A-N-A-E-N-N-F-N-L-D-G-N-R-L-Y-V-S-E-A-Y-A-G-Q-G-P-T-L-K-R-F-Q-P-H-A-Q-G-R-A-F-S-I-K-K-R-S-S-H-I-T-V-I-V-K-E-R-D"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-H-R-K-V-Q-R-G-R-M-K-G-K-A-T-R-G-N-F-I-A-Y-G-D-F-A-I-Q-A-T-E-C-A-W-I-T-S-N-Q-I-E-A-A-R-I-A-I-N-R-Y-V-K-R-G-G-K-L-W-I-K-I-F-P-D-K-P-V-T-Q-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-Y-W-V-A-V-V-K-P-G-R-V-L-F-E-M-S-D-V-T-E-E-Q-A-R-E-A-F-R-L-A-S-H-K-L-P-I-K-T-K-F-V-T-R-K-D-F-E-E-M-G-G-E-A-N-E-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-G-N-R-K-T-R-I-G-R-V-V-S-D-K-M-D-K-T-I-V-V-A-V-E-T-K-V-R-H-P-L-Y-G-K-T-V-N-K-T-T-K-F-K-A-H-D-E-K-N-E-A-K-L-N-D-R-V-Q-I-M-E-T-R-P-L-S-K-D-K-R-W-R-L-V-E-I-V-E-K-A-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-A-Q-T-M-L-K-V-A-D-N-S-G-A-K-E-I-M-C-V-R-V-L-G-G-S-K-R-K-W-G-N-I-G-D-I-I-V-A-S-V-K-S-A-T-P-G-G-V-V-K-K-G-E-V-V-K-A-V-V-V-R-S-A-K-G-L-R-R-A-D-G-S-Y-I-K-F-D-E-N-A-A-V-L-I-K-D-D-K-Q-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-K-D-F-N-K-I-L-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-N-K-I-H-V-R-K-Q-D-S-V-V-V-I-S-G-K-D-R-G-K-I-G-E-V-L-A-V-N-P-K-K-G-T-V-L-I-K-D-V-N-V-V-V-K-H-Q-K-A-N-K-E-N-M-Q-G-G-L-I-K-K-E-A-P-I-N-S-A-K-V-M-L-Y-C-T-K-C-K-T-A-T-R-I-S-K-K-V-L-D-D-G-T-K-V-R-V-C-K-K-C-G-E-T-F"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-V-P-R-L-K-E-K-Y-E-K-E-V-I-P-A-L-M-E-K-F-Q-Y-K-N-I-M-E-V-P-K-L-E-K-I-V-I-N-M-G-V-G-E-A-K-E-N-Q-K-V-L-E-S-A-V-A-D-M-Q-L-I-S-G-Q-K-P-I-L-T-R-A-K-K-S-V-A-N-F-K-I-R-E-N-M-P-I-G-C-K-V-T-L-R-K-N-K-M-F-E-F-A-D-K-L-M-N-V-A-L-P-R-V-R-D-F-R-G-V-S-S-K-S-F-D-G-R-G-N-Y-A-L-G-I-K-E-Q-L-I-F-P-E-V-E-Y-D-K-I-D-K-V-R-G-M-D-V-I-F-V-T-N-A-K-T-D-E-E-A-R-E-L-L-R-F-L-G-M-P-F-A-Q"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-R-K-A-L-I-E-K-W-K-K-E-P-K-Y-S-T-R-A-Y-T-R-C-K-I-C-G-R-P-H-S-V-L-K-K-Y-G-I-C-R-I-C-F-R-E-L-A-Y-K-G-E-I-P-G-C-R-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-L-L-T-R-I-R-N-A-N-V-V-R-H-G-V-V-E-L-P-S-S-K-I-K-K-A-M-A-N-I-L-L-Q-E-G-Y-L-K-D-I-E-E-Y-N-D-G-V-V-P-M-L-R-L-S-M-K-Y-G-K-G-K-E-R-I-V-T-G-L-K-R-I-S-K-P-G-L-R-V-Y-C-R-K-E-E-I-P-K-V-L-N-G-L-G-I-A-I-I-S-T-S-K-G-I-V-T-D-K-E-A-R-K-L-G-L-G-G-E-V-L-C-Y-V-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-Q-P-V-E-I-P-S-G-V-T-V-T-V-T-P-D-N-V-V-T-V-K-G-T-K-G-Q-L-E-K-A-M-H-K-D-M-K-I-A-V-E-D-N-K-V-V-V-T-R-P-S-D-S-K-N-H-K-A-L-H-G-L-T-R-A-L-I-N-N-M-V-I-G-V-T-E-G-F-S-K-T-L-Q-L-V-G-V-G-Y-K-A-Q-L-K-G-K-S-L-I-L-N-L-G-Y-S-H-P-I-E-V-A-S-I-E-G-V-T-F-E-I-P-D-A-N-T-V-V-V-K-G-I-N-K-E-L-V-G-S-V-A-A-D-I-R-T-F-R-K-P-E-P-Y-K-G-K-G-I-K-Y-S-D-E-V-I-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-L-N-K-V-Q-S-R-K-R-R-H-L-R-V-R-N-K-I-S-G-T-P-E-R-P-R-L-A-V-Y-R-S-E-K-N-I-Y-A-Q-V-I-D-D-V-N-G-T-T-L-V-S-A-S-T-L-D-K-D-F-S-A-K-A-G-S-N-K-E-A-A-K-L-V-G-G-I-V-A-K-K-A-L-D-K-G-I-K-Q-V-V-F-D-R-G-G-Y-I-Y-H-G-R-I-K-E-L-A-E-A-A-R-E-A-G-L-E-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-R-I-D-P-S-T-L-D-L-K-E-K-V-V-F-I-N-R-V-A-K-V-V-K-G-G-R-N-F-R-F-T-A-L-V-V-V-G-D-E-N-G-H-V-G-V-G-T-G-K-S-A-E-I-P-E-A-I-R-K-G-I-E-D-A-K-K-N-L-V-E-V-A-I-V-G-T-T-V-P-H-E-I-Y-G-E-F-G-T-G-R-V-L-I-M-P-A-S-E-G-T-G-V-I-A-G-G-P-V-R-A-V-L-E-L-A-G-L-N-D-V-R-A-K-S-L-G-S-N-N-P-R-N-M-V-N-A-T-I-N-G-L-S-R-L-R-T-V-E-Q-I-A-A-L-R-G-K-T-V-E-E-I-L-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-A-G-S-R-K-A-P-K-R-V-G-R-G-T-G-S-G-L-G-R-N-A-G-K-G-E-K-G-Q-N-A-R-S-G-G-G-V-R-P-G-F-E-G-G-Q-M-P-L-Y-R-R-L-P-K-R-G-F-T-N-I-F-A-K-T-I-T-A-V-N-V-D-R-L-N-I-F-E-D-G-T-E-V-T-I-D-A-L-I-E-K-G-I-I-K-K-V-N-D-G-V-K-I-L-G-N-G-E-L-K-K-K-L-V-V-K-V-N-K-Y-S-K-S-A-A-E-K-I-E-A-A-G-G-K-A-E-V-I"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-E-D-V-I-E-M-Q-G-T-V-L-E-S-L-P-N-A-M-F-E-V-E-L-E-S-G-Q-K-I-L-A-H-I-S-G-K-L-R-M-N-F-I-R-I-L-P-G-D-K-V-T-V-E-L-S-P-Y-D-L-T-R-G-R-I-T-W-R-A-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-D-L-P-K-E-K-R-V-E-I-G-L-T-Y-I-Y-G-I-G-L-T-S-S-R-K-I-I-K-A-T-S-V-N-P-E-T-R-V-K-D-L-T-E-E-E-V-N-A-L-R-D-Y-I-N-K-N-F-K-I-E-G-D-L-R-R-E-V-A-L-N-I-K-R-L-V-E-I-G-C-Y-R-G-I-R-H-R-R-G-L-P-V-R-G-Q-K-T-K-T-N-A-R-T-R-K-G-P-K-K-A-V-A-S-K-K-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-V-Q-K-N-K-K-T-R-R-R-K-E-K-K-N-I-E-H-G-C-A-H-I-K-S-T-F-N-N-S-I-V-T-I-T-D-V-N-G-N-A-L-S-W-S-S-A-G-G-L-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-T-A-A-K-T-A-M-E-H-G-L-K-S-V-D-V-F-V-K-G-P-G-S-G-R-E-A-A-I-R-S-L-Q-A-A-G-L-E-V-T-L-I-K-D-V-T-P-I-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-S-Y-L-A-K-P-Q-E-I-E-R-K-W-Y-V-I-D-V-A-G-K-P-L-G-R-A-A-S-Q-I-A-S-I-L-R-G-K-N-K-P-I-Y-T-P-N-V-D-T-G-D-Y-V-I-V-L-N-A-E-K-V-L-L-T-G-K-K-A-D-Q-K-M-F-R-H-H-T-L-Y-P-G-G-L-K-E-M-S-Y-K-D-A-I-A-K-K-A-D-F-V-F-Y-E-A-V-R-R-M-L-P-S-G-V-L-G-R-K-M-I-K-K-L-K-V-Y-K-G-E-E-H-N-N-E-A-Q-K-P-E-V-L-E-L-K-Y"} +{"text": "### FUNCTION Functions as the terminal component of an NADH peroxidase as the electron transport intermediary from NADH to Rbr2 ### SEQUENCE -M-S-V-K-N-A-M-T-A-D-F-L-R-S-A-Y-G-G-E-S-M-A-H-M-R-Y-L-I-W-G-E-E-A-E-N-S-N-Y-P-N-I-G-R-L-F-K-A-I-A-Y-S-E-H-I-H-A-K-N-H-F-N-V-L-K-E-D-L-Y-D-S-S-V-V-A-G-A-V-F-G-S-T-N-L-I-D-N-L-Q-G-A-I-N-G-E-L-H-E-I-K-Q-M-Y-P-V-Y-L-E-T-A-R-Y-Q-E-E-K-E-A-E-R-T-F-H-Y-A-L-E-A-E-K-I-H-A-K-L-F-Q-D-A-Q-D-S-A-K-E-N-K-D-I-N-I-G-K-V-Y-I-C-P-V-C-G-F-T-T-L-D-E-N-I-E-Q-C-P-I-C-G-V-K-K-D-K-F-Q-A-F"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-D-K-H-V-D-I-D-T-V-K-Y-I-S-K-L-S-K-L-K-F-T-D-N-E-A-K-K-L-A-G-E-F-E-A-I-L-G-H-F-E-T-I-D-K-V-D-L-S-D-I-N-V-N-E-F-D-E-V-N-T-E-F-R-K-D-V-P-K-V-F-E-D-K-K-K-L-M-Q-N-V-K-S-L-R-D-G-A-I-E-V-P-K-I-I-E"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-E-K-I-A-S-F-T-V-N-H-L-T-L-Q-P-G-V-Y-V-S-R-K-D-K-F-G-D-V-V-I-T-T-F-D-I-R-M-T-S-P-N-E-E-P-V-M-N-T-A-E-V-H-T-I-E-H-L-G-A-T-F-L-R-N-H-G-T-Y-A-E-K-T-V-Y-F-G-P-M-G-C-R-T-G-F-Y-L-I-L-Q-G-D-Y-T-S-N-D-I-V-P-L-L-R-E-M-Y-K-F-I-A-D-F-K-G-E-V-P-G-A-A-A-R-D-C-G-N-Y-L-D-M-N-L-P-M-A-N-Y-W-G-K-K-F-S-A-L-L-D-N-I-S-E-D-R-L-N-Y-P-E"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-Q-K-D-I-Q-P-E-Y-H-Q-D-A-V-V-K-C-A-C-G-N-T-F-T-T-G-S-T-K-K-E-L-K-V-D-I-C-S-K-C-H-P-F-F-T-G-Q-Q-K-I-V-D-V-G-G-R-V-E-K-F-R-K-K-Y-N-L-S-A-D-K"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-L-T-I-N-S-I-K-N-G-I-V-I-D-H-I-K-A-G-H-G-I-K-I-Y-N-Y-L-K-L-G-E-A-E-F-P-T-A-L-I-M-N-A-I-S-K-K-N-K-A-K-D-I-I-K-I-E-N-V-M-D-L-D-L-A-V-L-G-F-L-D-P-N-I-T-V-N-I-I-E-D-E-K-I-R-Q-K-I-Q-L-K-L-P-S-E-V-N-N-I-I-K-C-S-N-P-R-C-V-T-S-V-E-S-Y-I-P-H-K-F-K-L-V-D-E-E-K-G-E-Y-K-C-E-Y-C-D-E-I-Y-K-G-A-K-A-L-E-I"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-I-I-K-Q-A-E-F-I-I-S-A-A-W-K-K-Q-F-P-I-D-G-K-D-E-I-A-F-V-G-R-S-N-V-G-K-S-S-L-I-N-A-I-T-N-R-R-K-L-V-K-V-S-G-T-P-G-K-T-R-L-V-N-F-F-M-I-N-N-D-F-Y-F-V-D-L-P-G-Y-G-Y-A-K-V-S-K-K-E-L-E-K-W-S-Q-T-I-E-G-Y-L-V-G-R-E-Q-L-K-K-V-I-L-L-V-D-S-R-H-K-P-T-K-D-D-I-T-M-Y-N-W-I-K-Y-Y-D-Y-K-C-I-V-I-A-T-K-S-D-K-I-K-R-S-E-K-V-K-N-E-K-L-I-K-E-T-L-K-F-N-D-S-D-E-F-Y-F-F-S-S-A-T-K-Q-G-R-D-E-L-I-N-N-I-C-S-G-I-N-Y-S-E-N-S-L"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-L-R-Q-I-R-L-S-E-D-E-I-L-R-K-K-S-R-P-V-E-V-V-D-D-K-I-R-Q-I-L-D-D-M-L-D-T-L-Q-N-T-E-N-G-A-A-I-A-A-P-Q-V-G-I-L-K-Q-L-V-V-I-A-T-G-E-D-I-I-K-L-V-N-P-K-I-V-K-K-E-G-E-Q-E-V-V-E-G-C-L-S-I-P-N-V-Y-G-K-L-K-R-P-K-K-V-T-V-E-A-L-N-E-N-G-E-K-I-T-L-T-G-E-G-F-L-A-K-C-F-C-H-E-I-D-H-L-D-G-I-L-F-T-D-L-V-T-E-Y-I-K"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-I-I-S-K-N-K-N-F-I-V-N-E-E-I-R-Q-K-E-V-R-V-I-G-D-D-G-S-Q-L-G-V-I-P-T-S-E-A-L-K-L-A-E-E-K-E-L-D-L-V-A-M-S-P-N-A-V-P-P-V-C-K-I-M-D-F-G-K-F-V-Y-E-Q-T-K-K-E-K-E-N-K-K-N-Q-K-I-V-N-V-K-E-V-R-L-S-A-S-I-E-E-H-D-V-Q-I-K-S-N-N-A-R-K-F-L-I-A-G-D-K-V-K-V-A-V-R-F-R-G-R-Q-T-D-Y-A-F-K-G-R-K-I-L-D-N-F-F-E-K-I-N-D-V-G-V-I-E-K-P-A-K-L-E-G-K-N-M-I-M-I-L-A-P-K-K-A"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-A-V-N-A-R-K-N-H-R-K-V-L-K-L-A-K-G-Y-Y-G-G-K-S-K-L-F-K-T-A-N-E-S-V-I-R-A-L-R-N-A-Y-V-G-R-R-L-R-K-R-D-F-R-K-L-W-I-A-R-I-N-A-A-T-R-I-N-G-L-S-Y-S-K-F-I-N-G-I-K-L-A-G-I-D-M-N-R-K-M-L-S-E-I-A-I-N-D-P-K-A-F-S-E-L-V-E-V-A-K-K-Q-I-N-A"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-K-D-S-I-R-V-I-D-G-F-P-K-E-G-I-S-F-K-D-V-T-T-L-I-Q-D-K-E-A-Y-K-Y-S-V-D-K-I-G-E-Y-L-K-D-K-N-V-D-L-I-V-A-P-E-A-R-G-F-L-F-G-A-P-V-A-Y-K-I-G-A-G-F-I-P-V-R-K-K-G-K-L-P-C-E-T-V-E-V-T-Y-E-L-E-Y-G-E-D-I-L-E-M-H-K-D-A-I-K-K-G-Q-R-V-A-I-V-D-D-L-L-A-T-G-G-T-I-N-S-V-A-K-L-V-E-A-L-G-G-E-V-V-A-A-C-F-V-V-E-L-T-D-L-N-G-K-D-K-L-G-D-Y-D-T-M-S-L-V-K-Y-N-V"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-E-E-R-E-N-I-K-E-I-R-V-G-I-A-D-L-N-T-A-F-S-P-N-R-I-I-T-V-G-L-G-S-C-I-G-I-A-I-Y-D-S-K-N-K-L-G-G-L-S-H-I-M-L-P-D-S-T-Q-F-S-K-V-T-N-P-Y-K-F-A-D-L-A-I-P-I-L-I-K-K-M-E-G-M-G-A-N-I-R-N-M-K-A-K-I-A-G-G-A-S-M-F-N-F-S-D-K-N-M-N-M-D-I-G-N-R-N-G-I-S-V-K-K-V-L-K-E-L-N-V-P-L-L-S-Q-D-I-G-G-N-K-G-R-T-M-I-F-N-T-L-D-G-S-V-D-I-R-T-V-G-M-G-I-R-K-I"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-K-L-E-T-Q-Y-H-G-I-I-E-Y-N-E-N-N-I-I-N-L-V-K-G-M-S-G-F-E-N-L-K-K-F-I-L-V-G-I-E-N-N-E-V-F-S-L-F-H-S-M-E-D-K-E-T-A-F-I-V-S-S-P-F-Y-V-K-A-D-Y-E-V-N-L-S-E-E-L-V-K-E-L-K-I-D-S-E-K-D-V-L-I-I-N-T-V-N-L-S-K-D-I-K-K-M-T-T-N-L-G-A-P-I-I-I-N-I-N-K-H-L-G-K-Q-I-I-I-S-D-D-E-K-M-I-K-Y-P-M-I-H-S"} +{"text": "### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-V-M-G-R-K-K-G-E-S-I-L-I-G-D-D-I-E-I-T-I-V-S-L-D-E-N-S-V-K-I-A-I-N-A-P-R-E-V-T-I-L-R-K-E-L-Y-N-K-I-K-E-E-N-K-E-A-V-I-K-S-S-E-V-L-K-E-L-T-L-K-K"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-S-K-V-L-N-K-V-M-G-I-I-G-L-N-D-E-D-F-D-E-Y-E-D-E-V-M-E-E-K-A-I-A-R-E-N-S-Y-D-Y-D-E-K-L-N-D-K-N-S-S-N-S-N-N-K-V-V-N-I-H-T-A-S-S-V-K-V-V-I-V-K-P-K-D-Y-D-E-A-T-Q-I-C-D-D-L-K-N-R-K-I-V-V-V-N-V-T-D-L-E-P-K-T-A-Q-R-L-L-D-F-M-G-G-A-S-Y-V-L-N-G-E-L-L-E-I-D-K-G-V-Y-L-L-S-P-S-N-V-D-I-S-R-D-L-K-N-D-L-A-S-K-S-I-F-N-W-S-K"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-N-L-K-A-K-I-L-D-D-K-A-M-Q-R-T-L-T-R-I-A-H-E-I-I-E-K-N-K-G-I-D-D-I-V-L-V-G-I-K-R-R-G-V-P-I-A-D-R-I-A-D-I-I-E-E-I-E-G-S-K-V-K-L-G-K-V-D-I-T-L-Y-R-D-D-L-S-T-V-S-S-Q-P-I-V-K-D-E-E-V-Y-E-D-V-K-D-K-V-V-I-L-V-D-D-V-L-Y-T-G-R-T-C-R-A-A-I-E-A-I-M-H-R-G-R-P-K-M-I-Q-L-A-V-L-I-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-V-P-T-S-K-S-E-L-I-S-V-N-V-K-G-I-D-E-E-D-S-V-N-I-Y-E-L"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-A-G-D-L-R-K-G-T-T-F-E-L-D-G-Q-V-Y-N-V-V-D-F-L-H-V-K-P-G-K-G-A-A-F-V-R-T-K-L-K-N-V-I-T-G-A-V-T-E-T-T-F-N-P-T-A-K-M-Q-E-A-V-I-E-R-K-E-M-Q-Y-L-Y-S-D-E-S-F-Y-Y-F-M-D-Q-E-T-Y-E-Q-I-P-L-S-F-D-Q-V-E-N-A-I-K-Y-L-K-E-N-M-F-A-T-I-K-F-Y-K-G-E-A-F-S-V-E-A-P-N-F-V-E-L-K-I-V-S-C-E-P-G-V-K-G-N-T-T-S-N-V-M-K-P-A-T-L-E-T-N-A-V-V-Q-V-P-L-F-V-N-E-G-E-T-I-R-V-D-T-R-T-G-E-Y-M-E-R-V-Q"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-N-R-K-K-S-R-E-V-A-M-K-L-L-F-E-I-S-I-N-K-N-S-I-S-D-T-I-E-H-Y-K-E-N-N-E-I-E-N-L-D-F-E-Y-I-E-R-I-L-R-G-I-D-E-N-M-E-Y-I-D-S-K-I-E-E-S-S-K-K-W-K-I-S-R-I-S-K-I-N-I-T-I-L-R-M-A-A-Y-E-I-F-F-E-K-D-I-P-C-K-V-S-A-N-E-A-V-E-L-A-K-S-Y-A-E-E-N-S-F-S-F-V-N-G-V-I-G-N-L-I-N-S-S-E-E-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-P-S-K-K-E-S-Y-E-S-M-I-K-E-L-E-K-I-V-S-S-M-E-N-E-E-L-P-L-E-E-A-M-K-N-Y-E-D-G-V-K-L-C-D-K-L-Y-K-I-L-N-K-A-E-G-K-I-K-L-L-T-E-N-G-E-E-E-F-K-K-A-G-D-S-Y-E-Q"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-V-S-R-H-T-K-I-L-E-I-I-N-L-K-D-I-E-T-Q-E-E-L-A-E-E-L-R-R-S-G-M-E-V-T-Q-A-T-V-S-R-D-I-K-E-L-K-L-I-K-V-L-S-S-K-G-R-Y-K-Y-A-T-I-S-P-T-E-S-F-L-S-N-K-L-V-T-I-F-A-Q-T-V-L-N-V-D-R-V-N-N-M-V-V-V-K-T-I-S-G-S-A-N-A-A-A-E-A-I-D-S-L-N-L-D-G-I-A-G-S-I-A-G-D-N-T-I-F-I-L-S-R-S-E-E-T-A-F-N-I-V-Q-K-L-K-K-M-I-N-E"} +{"text": "### FUNCTION Acyl carrier protein ### SEQUENCE -M-R-E-L-T-S-E-I-K-K-E-I-R-D-I-V-Y-D-F-F-S-E-E-C-E-V-D-I-N-E-L-N-D-N-T-S-V-V-D-D-L-D-G-D-S-L-M-L-I-E-L-V-D-I-L-K-K-K-Y-S-L-N-I-Q-L-Q-S-I-G-K-Y-L-L-K-N-P-A-E-T-L-E-K-V-V-Q-T-T-Y-L-L-Y-E-Y-E-N-D-I-T-N-V-G-E-K"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-L-K-T-S-F-D-E-N-I-K-Q-K-H-K-I-E-K-P-K-M-Y-K-V-I-L-H-N-D-D-Y-T-T-M-E-F-V-I-E-I-L-I-N-V-F-N-K-V-P-A-N-A-V-K-I-T-F-D-V-H-K-N-G-I-G-I-A-G-V-Y-P-Y-D-I-A-A-T-K-I-N-E-V-K-K-L-A-Y-K-N-G-Y-P-L-K-L-T-M-G-E-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-D-K-A-K-K-Q-E-L-I-A-T-Y-S-R-K-E-G-D-T-G-S-P-E-V-Q-I-A-L-L-S-E-R-I-N-H-L-T-S-H-L-K-E-H-K-K-D-H-H-S-R-R-G-L-F-M-M-I-G-K-R-R-S-L-L-N-Y-L-E-S-V-D-I-E-R-Y-R-D-I-I-K-K-L-G-L-R-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-Y-R-A-G-R-I-N-E-E-V-K-K-A-I-S-S-I-I-Q-N-D-I-R-D-P-R-L-T-S-M-I-S-V-I-K-V-D-V-T-K-D-L-R-Y-A-K-A-Y-V-S-I-L-G-D-E-A-K-K-K-E-T-M-D-I-L-K-K-S-E-S-F-I-R-K-E-L-G-Y-A-V-K-L-R-Y-T-P-E-V-I-I-E-L-D-T-S-I-E-K-G-M-H-I-D-A-I-L-E-K-I-K-G-S-D-K-N-D-N-R"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-I-D-K-L-I-E-I-I-R-P-V-V-E-S-L-G-Y-E-F-Y-H-I-E-I-V-K-E-D-G-E-R-Y-L-R-V-Y-I-D-K-E-N-G-I-S-L-D-D-C-E-K-V-S-R-A-I-S-D-L-L-D-E-K-D-P-I-P-Y-S-Y-Y-L-E-V-S-S-P-G-I-Y-R-T-L-F-T-E-E-H-L-K-K-Y-I-G-N-T-V-D-I-K-L-K-S-S-L-E-K-S-T-N-Y-S-G-K-L-I-D-V-N-E-E-D-I-V-I-V-V-S-D-N-R-E-F-K-I-P-R-K-K-I-K-K-I-C-L-S-G-E-F"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-S-D-I-I-K-E-L-E-E-K-M-T-K-S-I-S-A-L-K-K-E-L-T-S-M-K-A-G-R-A-N-P-A-M-L-D-R-I-E-V-D-Y-Y-G-T-M-T-P-L-N-Q-L-A-N-I-S-V-P-E-S-R-V-L-M-I-Q-P-W-D-K-S-A-M-K-S-I-E-K-A-I-L-I-S-D-L-G-L-N-P-S-N-D-G-T-T-M-R-L-V-I-P-E-L-T-E-E-T-R-K-N-I-V-K-N-V-K-K-A-G-E-D-G-K-V-A-L-R-A-I-R-R-D-A-N-D-K-V-K-S-L-K-K-D-N-S-I-T-E-D-E-M-K-S-A-E-N-D-I-Q-K-K-T-D-S-Y-V-K-E-I-D-K-M-V-E-A-K-E-K-E-I-M-S-I"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-L-D-V-I-K-E-I-E-A-E-Q-I-R-T-D-L-P-S-F-N-V-G-D-T-V-R-I-E-V-R-I-K-E-G-E-K-E-R-L-Q-A-F-E-G-T-V-I-K-R-Q-N-G-G-L-R-E-T-F-T-V-R-R-V-A-Y-G-V-G-V-E-R-T-F-P-L-N-A-P-V-I-A-G-L-K-V-V-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-D-R-V-G-K-A-A-K-V-K-E-I-R"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-D-F-F-S-I-G-Q-I-I-N-T-H-G-V-R-G-E-L-K-I-Y-P-L-T-D-D-I-N-R-F-D-D-L-D-S-V-Y-V-D-N-E-I-K-K-V-I-S-V-K-K-Q-P-N-K-L-I-L-K-L-E-G-I-D-T-L-D-E-A-V-K-Y-K-N-K-Y-I-K-V-L-R-E-D-A-V-E-L-K-E-G-Q-Y-F-I-K-D-I-I-G-C-N-V-F-D-E-N-D-K-D-L-G-E-V-Y-D-V-I-S-T-K-N-N-D-V-Y-C-I-R-K-E-G-Q-Q-D-I-L-V-P-A-L-K-D-I-V-L-K-I-E-I-E-N-K-K-I-V-I-K-A-V-E-E-W-L-E-S"} +{"text": "### FUNCTION A probable RNA chaperone Forms a complex with KhpB which binds to cellular RNA and controls its expression Plays a role in peptidoglycan homeostasis and cell length regulation ### SEQUENCE -M-K-Q-L-L-E-T-I-A-K-S-L-V-D-C-P-D-E-V-Q-V-S-E-V-T-G-E-Q-S-I-I-L-E-L-K-V-A-P-E-D-M-G-K-V-I-G-K-Q-G-R-I-A-K-A-I-R-T-V-I-K-A-A-A-V-K-E-N-K-R-V-V-V-E-I-I"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-V-F-E-K-V-K-D-I-I-A-D-Q-L-G-I-D-A-T-E-I-K-M-E-S-S-F-I-D-D-L-G-A-D-S-L-D-I-V-E-L-I-M-A-L-E-E-E-F-D-I-E-M-P-D-E-E-A-E-K-V-S-S-V-G-D-V-V-N-Y-I-K-A-H-T-E-E"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-N-N-S-M-I-S-P-S-V-V-D-L-K-A-K-T-G-D-R-Y-S-L-V-V-I-T-S-K-R-A-R-Q-I-I-A-G-E-E-P-L-V-D-I-E-S-N-K-A-L-T-I-A-I-N-E-V-D-Q-D-K-I-K-F-D-L-P-I-E-G-I-N"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-L-G-I-D-V-G-N-K-T-I-G-V-A-L-S-D-P-L-G-F-T-A-Q-G-I-T-T-I-R-R-K-N-E-E-E-D-I-K-E-L-K-E-L-C-E-K-Y-E-V-D-T-I-V-C-G-L-P-K-N-M-N-G-T-I-G-F-Q-S-E-K-V-L-G-F-C-E-V-I-K-Q-N-I-N-V-P-I-K-M-W-D-E-R-L-T-T-V-T-A-N-R-A-M-L-E-A-D-L-S-R-K-K-R-K-K-L-V-D-K-V-A-A-T-Y-I-L-Q-G-Y-L-N-S-I"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-N-S-K-K-K-I-A-L-V-A-H-D-N-R-K-K-A-L-I-S-W-C-E-A-N-S-E-V-L-S-N-H-S-L-C-G-T-G-T-T-A-K-L-I-K-E-A-T-G-L-E-V-F-P-Y-K-S-G-P-M-G-G-D-Q-Q-I-G-A-A-I-V-N-E-D-I-D-F-M-I-F-F-W-D-P-L-T-A-Q-P-H-D-P-D-V-K-A-L-L-R-I-S-V-L-Y-D-I-P-I-A-M-N-E-S-T-A-E-F-L-I-K-S-P-I-M-K-E-Q-H-E-R-H-I-I-D-Y-Y-Q-K-I-R-K-D-N-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-T-M-R-E-P-R-F-K-L-S-R-R-L-G-V-N-I-Y-G-H-P-K-A-M-K-R-F-E-T-T-N-T-R-K-K-K-I-S-D-Y-G-M-H-L-I-E-K-Q-K-L-K-A-Y-Y-G-V-L-E-K-Q-F-S-R-Y-V-K-A-A-M-K-N-K-E-A-S-G-S-S-L-L-K-I-L-E-C-R-L-D-N-V-V-Y-R-I-G-F-A-N-S-I-R-Q-A-R-Q-M-V-S-H-G-L-I-L-V-N-G-K-K-L-D-I-P-S-Y-E-V-Q-V-G-D-V-V-S-L-K-E-K-H-R-Q-N-E-M-F-S-N-N-F-M-N-L-S-T-F-N-V-P-Y-I-E-K-N-P-D-E-F-S-G-K-L-L-R-L-P-N-I-D-E-I-P-I-K-V-N-E-V-A-V-I-E-F-Y-S-K"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-D-Y-F-L-I-G-I-G-G-A-C-G-S-I-V-R-Y-K-I-G-D-I-I-S-K-R-T-K-S-K-F-P-W-G-T-F-I-I-N-I-T-G-A-F-L-L-G-I-I-T-K-S-G-A-G-K-N-L-S-M-I-L-A-D-G-F-L-G-A-Y-T-T-F-S-T-F-M-Y-E-G-F-N-L-F-E-N-K-K-K-L-N-A-L-I-Y-I-L-S-S-I-I-I-G-I-L-G-F-Y-M-G-E-F-I-S-Q-L"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-K-K-Y-I-L-I-G-L-G-G-A-I-G-A-I-L-R-C-F-I-R-N-T-K-I-P-V-Y-K-G-E-F-P-I-S-T-L-M-I-N-L-S-G-A-F-I-L-A-V-I-L-I-T-A-N-E-I-W-S-F-N-E-E-I-R-L-G-I-A-T-G-F-V-G-A-Y-T-T-F-S-T-M-C-K-E-T-I-I-L-M-N-K-N-L-Y-F-L-A-F-C-Y-V-T-V-S-V-V-F-G-L-L-F-A-Y-F-G-A-L-S-A-R-K-I-L-S-R-L-L-K-V-R-K-E-D-E-K-A-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-R-F-M-G-P-R-F-K-L-A-R-H-L-G-V-N-V-F-G-H-P-K-A-L-N-R-G-V-K-Q-H-K-L-S-E-Y-G-E-Q-L-L-E-K-Q-K-L-R-A-Y-Y-G-V-L-E-K-Q-F-K-K-I-V-F-N-A-L-K-S-K-E-K-S-E-D-I-L-V-Q-S-L-E-R-R-L-D-N-L-V-Y-R-L-G-F-G-S-T-L-R-E-A-R-Q-M-V-S-H-G-H-I-L-V-N-G-Q-K-V-D-I-P-S-Y-K-V-N-I-G-D-E-V-S-L-R-S-K-S-R-K-I-Q-T-Y-A-S-N-F-T-T-I-I-P-A-V-T-Y-I-E-K-D-T-E-S-F-S-G-R-L-I-R-L-P-K-S-V-E-V-P-V-M-V-K-Y-S-K-V-L-E-F-Y-S-K-N"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-V-N-L-K-I-K-K-I-D-D-A-A-I-L-P-E-C-A-H-E-G-D-A-G-L-D-L-F-S-V-E-E-K-V-I-K-A-G-E-S-A-L-I-G-T-G-I-Q-M-E-L-P-P-E-T-E-A-Q-V-R-P-R-S-G-L-A-L-K-H-S-I-T-V-L-N-S-P-G-T-I-D-E-G-Y-R-G-E-V-K-I-I-L-I-N-H-G-K-E-D-F-K-V-E-K-S-M-K-I-A-Q-M-V-I-K-P-V-L-K-V-K-V-E-E-V-K-E-L-S-S-S-D-R-G-T-G-G-F-G-S-T-G-L-K-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-Y-I-D-N-R-Q-N-S-I-T-V-D-E-N-L-Q-N-T-I-R-E-V-I-D-Y-A-L-K-E-E-G-M-K-I-S-Y-E-V-S-V-I-F-V-D-N-E-T-I-R-E-I-N-R-E-N-R-E-V-D-K-V-T-D-V-L-S-F-P-M-L-E-Y-G-E-G-K-V-F-K-D-I-Y-E-E-C-D-F-E-D-E-Y-F-D-E-G-N-L-V-L-G-D-I-A-L-S-L-E-R-A-E-E-Q-S-K-E-Y-G-H-S-F-L-R-E-A-A-Y-L-T-V-H-S-V-L-H-L-M-G-Y-D-H-M-V-D-E-D-K-I-K-M-R-K-R-E-E-E-I-L-S-H-F-D-I-N-R"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-R-I-K-V-I-E-T-K-T-L-R-N-K-M-I-K-S-A-L-K-T-Y-I-K-K-F-E-A-A-F-E-A-K-N-V-E-E-S-K-T-A-F-A-T-V-S-K-A-L-D-M-A-A-S-K-G-I-I-H-K-N-K-A-A-R-K-K-S-R-L-A-L-K-L-N-S-L-N-A"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-K-K-K-A-I-F-G-G-T-F-N-P-I-H-N-A-H-L-N-I-A-A-K-S-I-E-K-L-Q-L-D-E-L-I-F-V-P-S-G-N-P-P-H-K-S-E-K-G-I-A-P-A-E-L-R-Y-E-M-V-K-E-A-I-K-D-N-C-K-F-R-I-D-D-Y-E-I-K-K-K-G-I-S-Y-T-Y-E-T-L-E-H-F-S-R-S-Q-K-D-V-D-W-F-F-I-A-G-L-D-S-L-M-D-L-D-K-W-R-N-V-N-T-I-L-S-L-C-K-F-I-V-F-N-R-S-G-Y-N-K-S-Q-V-L-E-Q-K-E-Y-L-E-K-K-Y-I-N-N-I-V-F-L-D-I-K-P-I-D-I-S-S-T-I-I-R-Q-K-I-R-E-N-E-Y-I-G-D-L-V-P-E-K-I-Y-D-I-I-K-K-N-K-L-Y-V"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-A-T-G-G-K-Q-Y-K-V-Q-E-G-D-A-I-Y-V-E-K-I-A-A-E-V-D-S-T-I-E-L-N-E-V-L-A-V-S-K-E-D-G-L-V-L-G-K-P-V-V-E-G-A-K-V-V-A-K-V-E-A-Q-G-K-S-K-K-I-I-V-F-K-Y-K-R-K-K-D-Y-R-R-K-R-G-H-R-Q-A-Y-T-K-L-V-I-E-K-I-Q-A"} +{"text": "### FUNCTION Dephosphorylates nucleoside monophosphates such as the 5' and 2'-phosphates of deoxyribonucleotides in vitro ### SEQUENCE -M-N-K-P-T-L-G-I-D-L-D-T-T-L-N-T-L-D-R-E-W-V-K-R-Y-N-E-I-Y-K-D-K-L-L-P-S-D-I-K-G-W-D-I-E-N-Y-V-K-P-E-C-G-K-K-I-Y-D-I-L-K-E-P-H-F-F-R-N-L-G-V-Q-P-F-A-E-T-A-L-E-E-L-T-S-I-F-N-I-Y-I-V-S-A-T-H-Y-K-V-C-E-D-K-G-N-W-I-K-E-K-F-P-F-I-S-Y-Q-N-I-I-F-C-H-N-K-G-L-V-H-L-D-I-L-I-D-D-N-P-L-N-L-E-N-F-K-G-N-K-I-L-F-D-A-H-H-N-K-S-E-N-R-F-V-R-A-R-D-W-Y-E-A-K-A-L-C-E-S-L-K-D-F-L"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-N-I-Y-S-L-F-V-V-A-I-A-L-S-L-D-A-F-G-V-A-L-S-I-G-L-D-S-C-V-K-R-K-N-K-L-L-F-A-I-S-F-G-F-F-Q-F-L-C-T-F-I-G-A-Y-S-G-F-L-F-N-T-Y-I-T-Y-V-P-Q-I-I-G-G-M-I-I-A-F-V-G-A-F-M-I-K-E-G-F-D-N-K-E-E-K-L-L-L-N-F-K-M-Y-F-V-L-G-I-S-V-S-I-D-A-A-V-V-G-F-T-M-F-N-K-I-S-S-N-Y-V-I-L-G-D-S-V-F-I-G-I-V-T-L-I-L-S-I-I-A-F-I-I-S-R-Y-L-K-R-I-Q-L-V-C-K-Y-A-D-Y-I-G-G-I-I-L-V-I-F-G-L-K-M-M-F-F"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-N-T-E-N-N-T-L-A-D-N-R-K-A-W-H-D-Y-F-I-E-E-T-Y-E-C-G-V-E-L-V-G-T-E-V-K-S-I-K-N-G-K-A-N-L-K-D-S-Y-A-E-I-R-N-G-E-V-F-A-C-N-M-H-V-S-P-Y-K-E-G-N-I-F-N-V-D-P-L-R-K-R-R-L-L-L-H-K-S-E-I-D-K-L-L-G-F-T-S-Q-K-G-Y-T-L-V-P-I-A-L-Y-L-K-N-R-R-V-K-V-K-L-A-V-A-V-G-K-K-N-Y-D-K-R-D-A-L-K-E-K-D-A-R-R-E-I-D-R-A-M-K-N-N-R"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-I-Y-E-G-K-L-I-S-K-N-L-K-F-G-I-V-A-G-R-F-N-E-F-I-V-S-K-L-L-S-G-A-V-D-A-L-K-R-H-G-C-D-E-D-S-I-E-L-A-W-A-P-G-A-F-E-I-P-L-I-S-Q-K-M-A-E-S-G-K-Y-D-A-V-I-C-L-G-A-V-I-R-G-A-T-S-H-F-D-Y-V-S-S-E-V-S-K-G-I-A-Q-T-S-L-K-T-G-C-P-V-I-F-G-V-L-T-T-D-N-I-E-Q-A-I-E-R-A-G-T-K-S-G-N-K-G-F-D-A-A-V-T-A-I-E-M-A-N-L-I-K-T-I-G-E"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-K-G-V-G-V-D-I-I-E-I-N-R-V-K-N-A-I-D-R-N-Y-K-F-I-E-K-L-F-S-R-R-E-I-A-Y-I-K-A-E-K-T-K-A-Q-Y-I-A-G-R-F-S-A-K-E-A-V-S-K-A-L-G-T-G-F-R-G-F-S-F-K-N-I-E-I-H-K-D-D-L-G-K-P-I-V-V-L-N-G-G-A-R-A-I-A-E-G-Y-G-K-Y-Q-V-Q-L-S-I-S-H-D-R-E-K-A-I-A-Y-A-V-L-E-V-F"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-E-F-Y-P-V-A-I-E-K-L-I-E-E-F-A-K-L-P-G-V-G-Y-K-T-A-Q-R-L-T-M-H-V-L-N-L-P-K-E-E-V-E-G-F-A-D-A-L-K-K-A-R-G-T-I-K-Y-C-S-V-C-G-N-Y-T-D-T-D-P-C-A-I-C-S-N-P-N-R-D-K-S-L-V-C-V-V-E-E-P-K-D-I-I-S-M-E-K-V-R-E-F-N-G-V-Y-H-V-L-H-G-V-I-S-P-M-L-G-K-G-P-D-S-I-K-L-R-E-L-V-S-R-M-N-G-K-V-K-E-V-I-V-A-T-N-P-N-V-D-G-E-A-T-A-M-Y-I-S-K-I-L-K-P-L-G-V-K-V-T-R-I-A-H-G-I-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-A-K-A-L-E-G-R-R-E-I"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-K-G-G-F-P-G-M-G-G-G-N-M-N-N-L-I-K-Q-A-Q-K-F-Q-K-Q-M-E-D-M-Q-K-E-I-E-N-K-E-F-T-A-T-V-G-G-G-A-V-S-A-T-V-S-G-K-K-E-I-T-E-I-K-I-K-P-E-V-V-D-P-D-D-V-E-M-L-Q-D-L-I-L-S-A-C-N-E-A-L-K-K-A-E-E-E-T-S-G-E-M-K-K-L-T-G-G-L-N-I-P-G-L"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-K-K-I-I-F-A-G-G-C-F-W-G-V-E-A-Y-F-N-T-I-D-G-V-L-N-T-K-V-G-Y-A-N-G-N-T-E-D-P-T-Y-E-D-V-C-T-D-S-T-G-Y-A-E-A-C-Y-I-E-Y-D-E-K-Q-L-K-L-E-K-L-I-D-A-Y-W-K-V-V-D-P-T-L-K-N-R-Q-G-H-D-E-G-T-Q-Y-R-T-G-I-Y-Y-V-D-E-E-D-L-K-V-I-L-E-S-K-D-K-E-Q-E-K-Y-D-A-P-I-V-T-E-I-L-P-L-K-N-F-Y-D-A-E-E-Y-H-Q-K-Y-L-D-K-N-P-N-G-Y-C-H-I-P-K-E-L-L-K-K-H"} +{"text": "### FUNCTION Oxygen-binding protein May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes The oxygen-binding site contains two iron atoms ### SEQUENCE -M-F-V-W-K-D-E-F-E-L-G-I-D-K-I-D-N-E-H-R-K-L-F-E-I-A-N-K-G-Y-E-L-L-K-N-E-F-Y-V-D-K-Y-D-K-I-M-D-I-I-V-E-L-K-E-Y-A-E-F-H-F-S-E-E-E-D-Y-L-A-S-I-G-Y-K-K-L-F-T-H-K-L-E-H-D-S-F-I-K-K-V-E-S-F-N-I-K-E-I-D-Y-D-Q-D-K-Y-I-Q-E-M-L-D-F-V-V-T-W-I-K-E-H-I-L-E-K-D-R-E-Y-I-D"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-N-F-R-V-K-R-E-K-D-F-K-A-I-F-K-E-G-T-S-F-A-N-R-K-F-V-V-Y-Q-L-E-N-Q-K-N-R-F-R-V-G-L-S-V-S-K-K-L-G-N-A-V-T-R-N-Q-I-K-R-R-I-R-H-I-I-Q-N-A-K-G-S-L-V-E-D-V-D-F-V-V-I-A-R-K-G-V-E-T-L-G-Y-A-E-M-E-K-N-L-L-H-V-L-K-L-S-K-I-Y-R-E-G-N-G-S-E-K-E-T-K-V-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-P-V-R-F-Y-Q-R-F-I-S-P-V-F-P-P-S-C-R-F-E-L-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-F-K-G-V-L-M-G-L-A-R-I-L-R-C-H-P-W-S-K-T-G-K-D-P-V-P-D-R-F-S-L-K-R-N-Q-E-G-E"} +{"text": "### FUNCTION Functions as a ribosomal silencing factor Interacts with ribosomal protein uL14 ### SEQUENCE -M-N-E-K-E-L-L-E-L-V-V-K-A-A-D-E-K-R-A-E-D-I-L-A-L-D-V-Q-D-L-T-S-V-T-D-Y-L-V-I-T-S-S-M-N-S-R-Q-L-D-A-I-A-A-N-I-R-E-K-V-A-Q-A-G-F-K-G-S-H-V-E-G-D-A-A-G-G-W-V-L-L-D-L-G-A-V-V-V-H-I-F-S-E-E-M-R-A-H-Y-N-L-E-K-L-W-H-E-A-N-S-V-D-I-S-E-A-L-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-N-E-I-I-A-Q-Y-A-R-H-E-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-W-E-I-N-H-L-N-E-H-I-K-Q-H-K-K-D-H-A-T-Y-R-G-L-M-K-K-I-G-R-R-R-N-L-L-A-Y-L-R-K-N-D-V-N-R-Y-R-E-L-I-N-S-L-G-L-R-R"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-E-K-T-Y-P-M-T-L-E-E-K-E-K-L-E-K-E-L-E-E-L-K-L-V-R-R-P-E-V-V-E-R-I-K-I-A-R-S-Y-G-D-L-S-E-N-S-E-Y-E-A-A-K-D-E-Q-A-F-V-E-G-Q-I-S-S-L-E-T-K-I-R-Y-A-E-I-V-N-S-D-A-V-A-Q-D-E-V-A-I-G-K-T-V-T-I-Q-E-I-G-E-D-E-E-E-V-Y-I-I-V-G-S-A-G-A-D-A-F-V-G-K-V-S-N-E-S-P-I-G-Q-A-L-I-G-K-K-T-G-D-T-A-T-I-E-T-P-V-G-S-Y-D-V-K-I-L-K-V-E-K-T-A"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-I-T-L-F-L-S-P-S-C-T-S-C-R-K-A-K-A-W-L-E-K-H-K-V-P-F-V-E-H-N-I-M-T-S-P-L-T-R-K-E-L-Q-H-I-L-S-L-T-E-N-G-T-D-D-I-I-S-T-R-S-K-I-F-Q-K-L-N-I-D-V-E-S-I-S-V-S-E-L-L-H-L-I-E-Q-Y-P-S-L-L-R-R-P-I-I-I-D-A-K-R-M-Q-I-G-F-N-E-D-E-I-R-A-F-L-P-R-S-Y-R-K-Q-E-L-K-E-A-R-M-R-A-G-I-S"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-K-K-E-Q-F-Y-P-L-G-I-F-L-A-A-M-L-G-G-L-V-R-Y-L-V-S-T-W-L-P-A-S-P-D-F-P-W-G-T-L-F-V-N-Y-L-G-I-F-C-L-I-Y-L-V-K-G-Y-L-V-Y-K-G-T-S-K-G-L-I-L-A-L-G-T-G-F-C-G-G-L-T-T-F-S-S-L-M-L-D-T-V-K-L-L-D-T-G-R-Y-L-S-L-I-L-Y-L-L-L-S-I-G-G-G-L-L-L-A-Y-Y-L-G-R-K-K-W"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-V-I-V-Y-L-A-I-A-C-G-L-G-A-L-V-R-Y-F-F-S-R-Y-N-Q-A-S-K-L-P-L-G-T-L-I-A-N-L-L-G-C-F-L-I-G-V-F-Y-N-H-V-E-S-K-E-V-Y-A-I-L-A-T-G-F-C-G-G-L-T-T-F-S-T-L-N-D-E-L-Q-R-L-L-S-D-K-K-V-F-Y-S-Y-L-T-L-T-Y-I-G-G-L-V-A-I-F-L-G-I-L-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-P-L-I-Q-S-L-T-E-G-Q-L-R-T-D-I-P-S-F-R-P-G-D-T-V-R-V-H-A-K-V-V-E-G-N-R-E-R-I-Q-I-F-E-G-V-V-I-A-R-K-G-A-G-I-S-E-N-Y-T-V-R-K-I-S-N-G-V-G-V-E-R-I-F-P-I-H-T-P-R-V-E-K-I-E-V-V-R-Y-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-Q-G-K-A-A-R-I-K-E-I-R-R"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-Q-I-L-E-R-Y-P-K-D-D-F-L-Q-E-Q-I-E-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-T-Y-A-I-I-K-T-G-G-K-Q-V-K-V-E-V-G-Q-A-V-Y-V-E-K-L-N-V-E-A-G-Q-E-V-T-F-N-E-V-V-L-V-G-G-E-N-T-V-V-G-T-P-L-V-A-G-A-T-V-V-G-T-V-E-K-Q-G-K-Q-K-K-V-V-T-Y-K-Y-K-P-K-K-G-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-N-A-I-N-A"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-G-E-G-K-V-V-A-Q-N-K-K-A-R-H-D-Y-T-I-V-D-T-L-E-A-G-M-V-L-T-G-T-E-I-K-S-V-R-A-A-R-I-N-L-K-D-G-F-A-Q-V-K-N-G-E-V-W-L-S-N-V-H-I-A-P-Y-E-E-G-N-I-W-N-Q-E-P-E-R-R-R-K-L-L-L-H-K-K-Q-I-Q-K-L-E-Q-E-I-K-G-T-G-M-T-L-V-P-L-K-V-Y-I-K-D-G-Y-A-K-L-L-L-G-L-A-K-G-K-H-D-Y-D-K-R-E-S-I-K-R-R-E-Q-N-R-D-I-A-R-V-M-K-A-V-N-Q-R"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-Y-I-E-M-V-D-E-T-G-Q-V-S-K-E-M-L-Q-Q-T-Q-E-I-L-E-F-A-A-Q-K-L-G-K-E-D-K-E-M-A-V-T-F-V-T-N-E-R-S-H-E-L-N-L-E-Y-R-N-T-D-R-P-T-D-V-I-S-L-E-Y-K-P-E-L-E-I-A-F-D-E-E-D-L-L-E-N-S-E-L-A-E-M-M-S-E-F-D-A-Y-I-G-E-L-F-I-S-I-D-K-A-H-E-Q-A-E-E-Y-G-H-S-F-E-R-E-M-G-F-L-A-V-H-G-F-L-H-I-N-G-Y-D-H-Y-T-P-E-E-E-A-E-M-F-G-L-Q-E-E-I-L-T-A-Y-G-L-T-R-Q"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-N-A-I-I-E-K-A-K-E-R-M-T-Q-S-H-Q-S-L-A-R-E-F-G-G-I-R-A-G-R-A-N-A-S-L-L-D-R-V-H-V-E-Y-Y-G-V-E-T-P-L-N-Q-I-A-S-I-T-I-P-E-A-R-V-L-L-V-T-P-F-D-K-S-S-L-K-D-I-E-R-A-L-N-A-S-D-I-G-I-T-P-A-N-D-G-S-V-I-R-L-V-I-P-A-L-T-E-E-T-R-R-D-L-A-K-E-V-K-K-V-G-E-N-A-K-V-A-V-R-N-I-R-R-D-A-M-D-E-A-K-K-R-E-K-A-K-E-I-T-E-D-E-L-K-T-L-E-K-D-I-Q-K-V-T-D-D-A-V-K-H-I-D-D-M-T-A-N-K-E-K-E-L-L-E-V"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-A-E-L-N-V-K-Q-N-E-K-N-S-A-Q-K-S-A-M-R-T-A-I-K-A-F-E-A-N-P-S-E-E-L-F-R-A-A-S-S-A-I-D-K-A-E-T-K-G-L-I-H-K-N-K-A-S-R-D-K-A-R-L-S-A-K-L-V-K"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-N-Y-F-N-V-G-K-I-V-N-T-Q-G-L-Q-G-E-M-R-V-L-S-V-T-D-F-A-E-E-R-F-K-K-G-A-E-L-V-L-F-D-E-K-D-Q-F-V-Q-T-V-T-I-A-S-H-R-K-Q-K-N-F-D-I-I-K-F-K-D-M-Y-H-I-N-T-I-E-K-Y-K-G-Y-S-L-K-V-A-E-E-D-L-N-D-L-D-D-G-E-F-Y-Y-H-E-I-I-G-L-E-V-Y-E-G-D-S-L-V-G-T-I-K-E-I-L-Q-P-G-A-N-D-V-W-V-V-K-R-K-G-K-R-D-L-L-L-P-Y-I-P-P-V-V-L-N-V-D-I-P-S-K-R-V-D-V-E-I-L-E-G-L-D-D-E-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-K-L-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-I-N-I-M-G-F-T-K-E-F-N-A-R-T-A-D-Q-A-G-M-I-I-P-V-V-I-S-V-Y-E-D-K-S-F-T-F-V-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-E-K-G-S-G-T-P-N-K-T-K-V-A-T-V-T-R-A-Q-V-Q-E-I-A-E-T-K-M-P-D-L-N-A-A-N-V-E-S-A-M-R-M-I-E-G-T-A-R-S-M-G-F-T-V-V-D"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-N-H-F-R-T-D-R-V-G-M-E-I-K-R-E-V-N-E-I-L-Q-K-K-V-R-D-P-R-V-Q-G-V-T-I-I-D-V-Q-M-L-G-D-L-S-V-A-K-V-Y-Y-T-I-L-S-N-L-A-S-D-N-Q-K-A-Q-I-G-L-E-K-A-T-G-T-I-K-R-E-L-G-R-N-L-K-L-Y-K-I-P-D-L-T-F-V-K-D-E-S-I-E-Y-G-N-K-I-D-E-M-L-R-N-L-D-K-N"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-D-A-I-A-T-I-V-E-L-V-R-E-V-V-E-P-V-I-E-A-P-F-E-L-V-D-I-E-Y-G-K-I-G-S-D-M-I-L-S-I-F-V-D-K-P-E-G-I-T-L-N-D-T-A-D-L-T-E-I-I-S-P-V-L-D-T-I-K-P-D-P-F-P-E-Q-Y-F-L-E-I-T-S-P-G-L-E-R-P-L-K-T-K-D-A-V-A-G-A-V-G-K-Y-I-H-V-G-L-Y-Q-A-I-D-K-Q-K-V-F-E-G-T-L-L-A-F-E-E-D-E-L-T-M-E-Y-M-D-K-T-R-K-K-T-V-Q-I-P-Y-S-L-V-S-K-A-R-L-A-V-K-L"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-A-S-I-I-F-S-A-K-D-I-F-E-Q-E-F-G-R-E-V-R-G-Y-N-K-V-E-V-D-E-F-L-D-D-V-I-K-D-Y-E-T-Y-A-A-L-V-K-S-L-R-Q-E-I-A-D-L-K-E-E-L-T-R-K-P-K-P-S-P-V-Q-A-E-P-L-E-A-A-I-T-S-S-M-T-N-F-D-I-L-K-R-L-N-R-L-E-K-E-V-F-G-K-Q-I-L-D-N-S-D-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-N-R-A-P-K-R-D-V-L-P-D-P-L-Y-N-S-Q-L-V-T-R-L-I-N-R-V-M-L-D-G-K-R-G-T-A-A-S-I-V-Y-G-A-F-E-Q-I-K-E-A-T-G-N-D-A-L-E-V-F-E-T-A-M-E-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-S-N-Y-Q-V-P-V-K-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-T-I-A-R-L-R-G-E-H-T-M-Q-D-R-L-A-K-E-I-L-D-A-A-N-N-T-G-A-A-V-K-K-R-E-D-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R-W"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-E-G-S-R-K-V-R-N-R-V-G-R-G-T-S-S-G-N-G-K-T-S-G-R-G-Q-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-L-P-K-R-G-F-T-N-I-N-A-K-E-Y-A-I-V-N-L-D-Q-L-N-V-F-E-D-G-A-E-V-T-P-V-V-L-I-E-A-G-I-V-K-A-E-K-S-G-I-K-I-L-G-N-G-E-L-T-K-K-L-T-V-K-A-A-K-F-S-K-S-A-E-E-A-I-T-A-K-G-G-S-V-E-V-I"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-L-R-Q-K-R-H-R-R-V-R-G-K-L-S-G-T-A-D-R-P-R-L-N-V-F-R-S-N-T-G-I-Y-A-Q-V-I-D-D-V-A-G-V-T-L-A-S-A-S-T-L-D-K-E-V-S-K-G-T-K-T-E-Q-A-V-A-V-G-K-L-V-A-E-R-A-N-A-K-G-I-S-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-N-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-V-I-V-L-P-A-G-V-E-L-A-N-N-D-N-V-V-T-V-K-G-S-K-G-E-L-T-R-E-F-S-K-D-I-E-I-R-V-E-G-T-E-I-T-L-H-R-P-N-D-S-K-E-M-K-T-I-H-G-T-T-R-A-L-L-N-N-M-V-V-G-V-S-E-G-F-K-K-E-L-E-M-R-G-V-G-Y-R-A-Q-L-Q-G-S-K-L-V-L-A-V-G-K-S-H-P-D-E-V-E-A-P-E-G-I-T-F-E-L-P-N-P-T-T-I-V-V-S-G-I-S-K-E-V-V-G-Q-T-A-A-Y-V-R-S-L-R-S-P-E-P-Y-K-G-K-G-I-R-Y-V-G-E-F-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-N-R-L-K-E-K-Y-L-N-E-V-V-P-A-L-T-E-Q-F-N-Y-S-S-V-M-A-V-P-K-V-D-K-I-V-L-N-M-G-V-G-E-A-V-S-N-A-K-S-L-E-K-A-A-E-E-L-A-L-I-S-G-Q-K-P-L-I-T-K-A-K-K-S-I-A-G-F-R-L-R-E-G-V-A-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-V-S-V-S-L-P-R-V-R-D-F-H-G-V-P-T-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-N-F-D-D-V-D-K-T-R-G-L-D-I-V-I-V-T-T-A-N-T-D-E-E-S-R-A-L-L-T-G-L-G-M-P-F-A-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-L-Y-D-V-I-K-K-P-V-I-T-E-S-S-M-A-Q-L-E-A-G-K-Y-V-F-E-V-D-T-R-A-H-K-L-L-I-K-Q-A-V-E-A-A-F-E-G-V-K-V-A-N-V-N-T-I-N-V-K-P-K-A-K-R-V-G-R-Y-T-G-F-T-N-K-T-K-K-A-I-I-T-L-T-A-D-S-K-A-I-E-L-F-A-A-E-A-E"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-A-Y-L-K-G-I-I-T-K-I-T-A-K-Y-I-V-L-E-T-N-G-I-G-Y-I-L-H-V-A-N-P-Y-A-Y-S-G-Q-V-N-Q-E-A-Q-I-Y-V-H-Q-V-V-R-E-D-A-H-L-L-Y-G-F-R-S-E-D-E-K-K-L-F-L-S-L-I-S-V-S-G-I-G-P-V-S-A-L-A-I-I-A-A-D-D-N-A-G-L-V-Q-A-I-E-T-K-N-I-T-Y-L-T-K-F-P-K-I-G-K-K-T-A-Q-Q-M-V-L-D-L-E-G-K-V-V-V-A-G-D-D-L-P-A-K-V-A-V-Q-A-S-A-E-N-Q-E-L-E-E-A-M-E-A-M-L-A-L-G-Y-K-A-T-E-L-K-K-I-K-K-F-F-E-G-T-T-D-T-A-E-N-Y-I-K-S-A-L-K-M-L-V-K"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-F-Y-Q-E-T-K-E-R-S-P-R-R-E-T-T-R-T-L-Y-L-D-I-D-A-S-S-E-L-E-G-R-I-T-A-R-Q-L-V-E-E-N-R-P-E-Y-N-I-E-Y-I-E-L-L-S-D-K-L-L-D-Y-E-K-E-T-G-A-F-E-I-T-E-F"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-K-L-L-V-G-L-G-N-P-G-D-K-Y-F-E-T-K-H-N-V-G-F-M-L-I-D-Q-L-A-K-K-Q-N-V-T-F-T-H-D-K-I-F-Q-A-D-L-A-S-F-F-L-N-G-E-K-I-Y-L-V-K-P-T-T-F-M-N-E-S-G-K-A-V-H-A-L-L-T-Y-Y-G-L-D-I-D-D-L-L-I-I-Y-D-D-L-D-M-E-V-G-K-I-R-L-R-A-K-G-S-A-G-G-H-N-G-I-K-S-I-I-Q-H-I-G-T-Q-V-F-N-R-V-K-I-G-I-G-R-P-K-N-G-M-S-V-V-H-H-V-L-S-K-F-D-R-D-D-Y-I-G-I-L-Q-S-V-D-K-V-D-D-S-V-N-Y-Y-L-Q-E-K-N-F-E-K-T-M-Q-R-Y-N-G"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-I-I-E-G-P-V-I-K-F-G-D-K-I-D-T-D-I-I-I-P-A-R-Y-L-K-Y-T-D-P-Q-Y-L-A-Q-H-V-M-E-P-L-D-P-E-F-Y-K-K-A-S-K-G-V-I-I-V-A-G-K-V-F-G-M-G-S-S-R-E-Q-A-A-I-A-L-K-A-A-G-V-K-A-V-V-A-E-S-F-A-R-I-F-Y-R-N-A-I-N-N-G-L-P-V-I-T-L-P-N-S-T-K-E-I-D-E-N-S-Y-V-K-I-D-V-E-T-G-E-I-L-V-G-N-K-V-L-K-G-K-G-I-T-G-M-A-L-E-I-L-Q-A-G-G-I-M-E-Y-L-K-K-M-Q-T-V-N-R-N"} +{"text": "### FUNCTION eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA ### SEQUENCE -M-S-S-E-K-E-Y-V-E-M-L-D-R-L-Y-S-K-L-P-E-K-G-R-K-E-G-T-Q-S-L-P-N-M-I-I-L-N-I-G-N-T-T-I-I-R-N-F-A-E-Y-C-D-R-I-R-R-E-D-K-I-C-M-K-Y-L-L-K-E-L-A-A-P-G-N-V-D-D-K-G-E-L-V-I-Q-G-K-F-S-S-Q-V-I-N-T-L-M-E-R-F-L-K-A-Y-V-E-C-S-T-C-K-S-L-D-T-I-L-K-K-E-K-K-S-W-Y-I-V-C-L-A-C-G-A-Q-T-P-V-K-P-L"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-P-K-K-D-R-A-Q-E-A-P-S-R-D-V-P-R-P-E-E-G-Q-T-I-C-V-V-K-K-M-L-G-G-D-H-L-I-V-L-C-M-D-G-K-E-R-L-A-R-I-P-G-K-I-R-K-K-M-W-M-R-E-G-D-V-V-L-V-G-I-W-D-F-Q-P-N-R-C-D-I-L-Y-K-Y-G-N-D-E-I-K-R-L-V-N-E-N-I-I-S-R-E-V-I-D-Q-L-R-G"} +{"text": "### FUNCTION Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7 ### SEQUENCE -M-E-W-N-Y-V-I-P-G-I-P-D-N-L-F-E-R-D-E-E-I-P-M-T-K-E-E-I-R-A-L-A-L-S-K-L-R-I-K-K-G-D-K-V-L-D-I-G-C-G-T-G-S-I-T-V-E-A-S-L-L-V-G-N-S-G-R-V-Y-G-I-D-K-E-E-K-A-I-N-L-T-R-R-N-A-E-K-F-G-V-L-N-N-I-V-L-I-K-G-E-A-P-A-I-L-S-T-I-N-E-K-F-D-R-I-F-I-G-G-G-S-E-K-I-K-E-I-I-S-A-S-W-E-I-I-N-K-G-G-R-I-V-I-D-A-I-L-L-E-T-V-N-N-A-L-S-A-M-E-K-I-G-F-V-N-L-E-I-T-E-V-I-I-A-K-G-M-K-T-K-V-G-T-A-M-M-A-R-N-P-I-F-I-I-S-G-E-K-P"} +{"text": "### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-L-E-E-S-K-N-A-L-R-V-F-I-T-G-N-P-G-V-G-K-T-T-I-L-L-F-L-I-N-K-L-S-E-N-N-Y-K-V-A-G-F-Y-C-P-E-V-R-E-N-G-R-R-I-G-F-R-I-V-D-I-T-T-N-E-G-D-W-L-A-K-E-N-A-P-G-R-V-K-I-G-K-Y-T-V-L-E-D-S-A-K-R-I-T-E-I-T-L-S-N-I-N-K-A-D-V-L-A-I-D-E-I-G-P-M-E-L-K-I-P-T-I-K-K-L-I-E-T-I-L-N-N-Q-K-P-L-I-A-V-L-H-R-T-Q-K-P-M-G-G-R-I-Y-V-I-T-V-E-N-R-D-S-I-K-Y-E-I-L-N-Y-I-L-S-S-L-D"} +{"text": "### FUNCTION CRISPR ### SEQUENCE -M-S-S-P-G-G-S-Q-Q-V-E-W-V-F-I-P-V-I-K-D-V-T-Y-E-F-K-V-D-N-N-D-N-I-T-E-L-Y-V-N-G-N-K-L-G-P-A-S-S-L-E-M-D-F-Y-F-D-V-D-V-S-N-N-Q-V-R-K-F-N-N-V-F-V-L-F-G-V-I-A-T-K-D-S-N-K-I-K-M-Q-L-T-L-N-P-C-D-F-V-R-G-F-V-F-P-S-Q-D-P-S-Q-L-N-N-I-F-A-S-N-N-K-V-S-V-S-E-K-A-F-A-I-L-N-R-K-K-E-G-A-V-S-S-T-I-N-V-Y-I-T-Q-N-T-Y-T-G-N-T-K-I-E-K-I-Q-Q-N-T-I-I-I-E-K-N-T-G-I-V-F-K-I-P-N-D-M-L-N-I-F-R-Y-S-T-T"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-V-A-T-L-G-G-G-C-F-W-C-T-E-A-V-Y-K-R-V-K-G-V-I-S-V-K-P-G-Y-S-G-G-H-V-P-N-P-T-Y-E-D-V-C-T-D-T-T-G-H-A-E-V-V-Q-I-T-F-D-S-S-I-I-S-Y-R-E-I-L-E-I-F-F-E-I-H-D-P-T-T-L-N-R-Q-G-N-D-V-G-T-Q-Y-R-S-I-I-L-Y-H-N-E-E-Q-R-K-I-A-E-E-M-I-R-E-V-E-K-R-I-G-K-K-V-V-T-E-L-K-P-F-E-V-F-Y-E-A-E-D-Y-H-H-D-F-Y-D-K-H-K-Y-N-P-Y-C-R-L-V-I-S-P-K-V-K-K-F-M-K-L-F-P-D-K-V-K-I-H-E-G"} +{"text": "### FUNCTION CRISPR ### SEQUENCE -M-E-A-S-E-P-V-A-E-T-I-S-K-R-F-W-T-L-I-K-M-L-R-F-Y-V-V-L-R-R-F-G-Y-I-D-P-L-I-Y-S-I-D-P-K-Q-I-K-D-V-L-S-E-A-L-R-E-F-V-S-Y-T-S-S-S-S-S-R-S-I-V-I-Y-D-D-P-K-N-P-V-T-A-Q-A-P-C-L-V-V-A-K-R-D-E-I-P-Q-N-F-P-S-I-Y-R-Y-T-I-Y-K-I-D-K-S-S-E-Y-C-I-S-P-L-V-V-N-D-K-Y-A-T-L-I-T-P-N-E-S-V-I-K-E-F-F-D-K-L-D-S-N-I-Q-Y-A-R-V-L-A-S-L-A-V-G-G-E"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-K-I-L-G-F-T-F-P-D-D-L-L-Y-E-P-E-K-H-V-W-V-R-I-E-D-N-S-V-V-S-I-G-V-T-D-L-G-Q-Y-M-A-G-K-I-F-Q-V-T-A-K-Q-K-G-E-K-V-N-G-R-S-V-L-F-S-I-E-S-A-K-W-I-G-K-F-R-L-P-I-E-G-E-V-F-D-V-N-E-E-V-V-K-N-P-S-I-I-N-E-R-P-Y-D-S-W-I-V-K-I-R-V-E-D-M-D-I-I-K-R-T-F-K-P-I-Q-E-V-Y-K-Q-F-E-E-E-A-K-R-V-V-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-V-V-E-S-N-C-E-I-P-E-N-L-Y-Y-F-I-E-G-K-N-T-V-W-A-K-L-E-S-P-D-T-I-V-V-G-I-T-D-L-A-Q-T-M-A-G-K-I-V-K-V-R-I-K-K-K-G-T-K-V-E-K-G-R-P-V-A-T-M-E-S-G-K-W-A-G-P-V-P-A-P-V-T-G-E-V-V-E-V-N-A-E-A-E-K-S-P-I-I-I-N-Q-D-P-Y-G-K-G-W-L-V-K-M-K-M-S-N-P-E-E-L-K-Q-L-F-S-G-Q-A-A-I-Q-K-L-K-E-L-I-A-S-E-K-L-T-C-K-R-L"} +{"text": "### FUNCTION Involved in ribosome biogenesis ### SEQUENCE -M-K-W-K-M-R-K-C-P-K-D-N-I-Y-T-F-K-D-T-C-Q-I-C-G-S-K-T-V-I-P-H-P-S-R-F-S-P-E-D-K-Y-V-K-Y-R-I-E-L-K-K-G-I-T-L-N-C"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-T-E-K-L-N-E-I-V-V-R-K-T-K-N-V-E-D-H-V-L-D-V-I-V-L-F-N-Q-G-I-D-E-V-I-L-K-G-T-G-R-E-I-S-K-A-V-D-V-Y-N-S-L-K-D-R-L-G-D-G-V-Q-L-V-N-V-Q-T-G-S-E-V-R-D-R-R-R-I-S-Y-I-L-L-R-L-K-R-V-Y"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-N-E-M-K-V-G-R-Y-V-V-L-T-D-R-L-Y-T-E-T-D-E-W-V-V-L-S-N-D-N-V-A-V-I-G-I-T-D-Y-A-Q-K-K-L-R-D-I-V-G-I-E-L-P-Q-L-Q-K-E-V-K-A-G-E-S-V-G-V-I-E-S-V-K-A-A-A-D-I-F-S-P-L-S-G-I-I-V-E-V-N-N-K-L-L-E-H-P-E-I-I-N-K-D-P-Y-G-E-G-W-I-F-K-L-K-A-S-K-L-S-E-E-K-E-K-L-L-S-P-E-K-Y-I-E-K-I-K-G-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-G-T-P-S-F-G-K-M-N-K-S-H-T-H-I-R-C-R-R-C-G-R-N-A-Y-N-V-S-K-H-Y-C-A-A-C-G-F-G-R-T-K-K-I-R-R-Y-S-W-Q-N-K-K-V-N-G-V-R-I-R"} +{"text": "### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-I-Q-M-A-L-A-T-E-K-A-L-K-L-I-E-S-Y-N-T-L-T-L-I-V-D-K-S-D-T-K-D-D-I-K-K-S-V-E-R-L-F-N-V-K-V-V-K-V-N-V-V-I-T-P-Q-G-Y-K-K-A-Y-V-K-L-A-P-E-Y-K-A-S-D-I-A-H-K-L-G-I-F"} +{"text": "### FUNCTION Broad-specificity nucleoside monophosphate kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-I-I-I-V-T-G-T-P-G-V-G-K-T-V-A-S-K-K-L-S-E-A-L-N-L-N-Y-L-S-L-S-Q-F-V-I-E-N-K-L-Y-T-E-Y-D-E-L-R-Q-S-Y-I-I-D-E-D-K-V-K-E-E-L-E-K-I-I-S-T-S-H-L-V-I-E-T-I-Y-P-S-L-V-S-T-A-D-L-V-V-V-L-R-K-N-P-F-S-L-Y-N-E-L-K-G-R-G-W-A-D-I-K-V-A-E-N-V-E-A-E-I-L-G-V-I-S-Q-E-A-R-E-A-F-K-D-K-V-C-E-V-D-T-T-E-M-S-T-E-Q-I-L-N-K-I-L-N-K-Q-C-D-G-P-I-E-W-L-V-D-T-K-V-Q-R-F-L-E-E-L-D-K-I-I-S-S-Y-E-N-D-I"} +{"text": "### FUNCTION Endonuclease that removes tRNA introns Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp ### SEQUENCE -M-V-K-A-L-L-V-G-S-K-V-L-V-P-S-I-D-E-S-R-Y-L-Y-S-N-G-F-Y-G-K-P-I-G-I-S-K-P-K-G-P-K-D-I-V-R-P-L-E-L-S-L-I-E-S-V-Y-L-T-K-K-G-L-I-N-V-V-D-K-N-G-D-L-L-E-Y-K-K-L-Y-E-Y-S-A-M-K-I-N-K-F-E-I-L-Y-K-V-Y-E-D-L-R-E-K-G-F-I-V-R-S-G-V-K-Y-G-A-D-F-A-V-Y-T-L-G-P-G-L-E-H-A-P-Y-V-V-I-A-V-D-I-D-E-E-I-T-P-H-E-L-L-S-F-G-R-V-S-H-S-T-K-K-R-L-V-L-A-L-V-D-R-K-S-E-G-I-R-Y-I-M-F-K-W-V-K-M"} +{"text": "### FUNCTION Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A ### SEQUENCE -M-E-V-R-N-N-N-K-V-N-L-C-F-S-F-D-N-L-R-N-E-L-S-R-P-Y-G-I-L-F-I-N-N-K-I-F-L-E-F-I-S-K-S-I-Q-R-G-S-R-I-I-T-V-G-D-Y-V-S-R-V-L-E-E-N-G-I-V-P-F-L-E-V-I-D-G-K-T-K-R-T-I-T-Q-N-R-A-I-T-R-N-K-E-Y-K-V-T-N-E-A-G-K-I-R-F-E-I-F-E-I-M-E-N-I-L-K-D-R-E-G-G-V-V-F-V-D-G-E-E-D-L-L-V-I-P-V-T-L-S-A-N-H-G-D-I-V-I-Y-G-Q-P-N-A-G-A-V-V-I-I-V-N-E-M-I-R-W-R-V-R-D-I-L-E-K-A-I-V-K-E-C"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-Q-E-K-S-I-R-L-G-I-V-V-A-E-F-N-Y-D-I-T-Q-L-M-L-Q-K-A-L-S-H-A-R-F-L-N-V-E-V-K-V-V-I-K-V-P-G-T-F-D-M-P-L-A-I-K-K-L-L-E-K-D-F-I-D-A-V-V-T-L-G-A-V-I-K-G-E-T-K-H-D-E-L-V-A-S-Q-T-A-R-K-I-V-D-L-S-T-E-F-N-K-P-V-T-L-G-I-I-G-H-G-A-T-H-E-Q-A-V-E-R-I-E-E-Y-A-T-R-A-V-E-A-A-I-K-L-V-Q-R-T-R-K-L-D-E-L-K-E-I-K-E-T-V-I-I-E"} +{"text": "### FUNCTION Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs ### SEQUENCE -M-T-T-H-V-I-L-V-A-R-A-F-G-A-K-G-V-Y-I-E-G-K-D-E-K-M-V-K-S-I-L-K-V-I-D-S-W-G-G-S-S-Y-F-L-V-K-E-I-E-N-G-K-S-I-V-N-E-W-K-E-K-G-G-T-I-I-H-L-T-M-Y-G-I-N-I-N-D-F-Q-D-R-F-E-K-I-K-Y-P-L-L-I-I-V-G-A-E-K-V-E-G-W-Y-Y-H-N-A-D-Y-N-I-A-I-G-N-Q-P-H-S-E-V-A-A-L-A-I-F-L-D-R-I-Y-K-G-R-E-L-Y-M-E-F-E-D-A-K-I-K-I-L-P-Q-K-A-G-K-K-V-I-R-S-G"} +{"text": "### FUNCTION Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP ### SEQUENCE -M-S-L-R-D-L-K-E-E-N-R-I-V-I-W-P-S-Y-F-F-S-P-T-R-S-K-G-R-R-L-A-R-I-P-Y-K-I-K-T-E-E-L-V-S-T-L-R-E-L-G-L-D-P-I-V-I-E-N-K-K-Y-P-R-D-R-K-I-N-F-L-I-A-V-K-K-V-K-S-K-N-Y-T-L-K-I-I-H-N-A-L-M-G-T-R-Q-T-N-P-N-K-S-N"} +{"text": "### FUNCTION Plays a role in the inhibition of the host NF-kappa-B pathway by preventing ubiquitin binding-dependent regulation of host IKBKB activation by IKBKG/NEMO ### SEQUENCE -M-C-L-V-A-P-M-Q-C-G-C-A-S-C-V-R-I-L-D-A-L-L-S-A-M-E-A-L-V-Q-M-R-L-L-S-E-E-E-K-T-S-C-A-S-Q-F-L-E-L-A-I-F-A-V-E-N-C-R-G-G-R-Q-A-L-L-Q-A-R-G-E-P-A-S-L-G-E-V-A-G-K-G-P-A-A-D"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-K-S-K-F-R-P-L-H-D-R-V-V-V-R-R-V-E-S-E-S-K-T-A-G-G-I-I-I-P-D-T-A-K-E-K-P-Q-E-G-E-I-I-A-V-G-S-G-A-R-D-E-A-G-K-L-V-P-L-D-V-K-A-G-D-R-I-L-F-G-K-W-S-G-T-E-V-K-L-N-G-E-D-L-L-I-M-K-E-S-D-I-M-G-I-I-G"} +{"text": "### FUNCTION Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates Responsible for the transcription of early, intermediate and late genes DNA-dependent RNA polymerase associates with the early transcription factor ### SEQUENCE -M-V-F-A-L-V-C-A-S-C-G-R-D-L-S-E-V-R-Y-R-L-L-I-E-R-Q-K-L-S-D-V-L-R-N-L-T-H-M-C-C-R-L-K-L-A-T-Q-I-E-P-Y-R-N-L-T-V-Q-P-L-L-D-I-N"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-T-T-F-S-Q-K-P-A-D-V-V-K-K-W-I-L-I-D-A-E-G-L-V-V-G-R-L-A-T-V-I-A-N-H-L-R-G-K-H-K-P-T-F-T-P-H-V-D-D-G-D-N-V-I-V-I-N-A-D-K-V-V-F-T-G-K-K-F-T-D-K-V-Y-Y-W-H-T-G-H-P-G-G-I-K-E-R-T-A-R-Q-L-L-E-G-R-F-P-E-R-V-V-E-K-A-V-E-R-M-V-P-R-G-P-L-G-R-R-Q-M-K-N-L-R-V-Y-A-G-A-E-H-P-H-V-A-Q-Q-P-E-V-L-D-V-A-K-L-N-S-K-N-K-K-V-A"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-G-G-K-T-L-T-R-A-D-L-A-E-A-V-Y-R-K-V-G-L-S-R-T-E-S-A-E-L-V-E-A-V-L-D-E-I-C-E-A-I-V-R-G-E-T-V-K-L-S-S-F-A-T-F-H-V-R-S-K-N-E-R-I-G-R-N-P-K-T-G-E-E-V-P-I-L-P-R-R-V-M-T-F-K-S-S-N-V-L-K-N-R-I-L-R-S-H-Q-N-S-K-A-K-G-G-K"} +{"text": "### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-D-P-L-S-V-F-F-L-V-V-A-A-A-A-V-C-T-L-L-L-Q-A-Y-A-V-Y-E-N-F-D-S-I-L-E-F-N-D-A-H-A-S-L-E-Y-S-K-S-L-G-G-S-Y-I-D-K-H-V-F-D-P-N-D-G-V-A-D-V-T-Q-K-W-R-C-A-L-Y-G-K-V-Y-V-S-A-S-A-F-G-F-Y-A-Q-P-D-G-S-K-R-T-F-S-T-R-D-D-C-V-D-F-T-F-G-T-A-D-T-S-R-V-V-N-P-C-T-D-P-N-G-A-Q-A-E-D-C-A-F-L-K-S-V-L"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-R-H-A-N-K-R-G-A-A-R-L-A-A-V-Q-A-L-Y-Q-M-D-V-A-G-S-G-V-F-E-I-T-A-E-Y-E-A-F-R-L-G-K-E-V-D-G-A-L-Y-R-E-A-D-A-Q-W-F-R-A-I-L-T-G-V-V-E-D-Q-K-T-I-D-P-V-I-R-Q-A-L-T-D-D-W-P-L-S-R-L-D-S-T-L-R-A-I-L-R-A-G-V-Y-E-L-M-K-R-E-D-V-P-V-A-V-I-V-S-E-Y-V-D-I-A-K-A-F-Y-E-E-D-E-P-K-L-V-N-A-V-L-D-R-V-S-R-R-V-R-G-E-G-R-G-K-D-A-S"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-Y-C-Q-S-E-D-T-Q-V-K-D-S-R-P-A-E-D-G-A-A-I-R-R-R-R-V-C-P-D-C-G-G-R-F-T-T-F-E-R-V-Q-L-R-D-L-V-V-V-K-K-S-G-R-K-V-P-F-D-R-D-K-L-L-R-S-V-E-I-A-V-R-K-R-N-V-D-P-E-R-I-D-R-A-V-T-G-I-V-R-Q-L-E-S-S-G-E-T-E-V-A-S-G-E-V-G-R-L-V-M-E-A-L-K-S-L-D-D-V-A-Y-V-R-F-A-S-V-Y-R-N-F-R-E-A-K-D-F-H-E-L-L-G-E-L-K-G-D-E-D-K-S-E-E-D-A-G"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-K-V-I-A-S-S-L-R-K-G-N-V-V-D-K-D-G-K-L-Y-V-I-L-F-A-E-N-I-H-P-G-K-G-T-P-V-T-Q-L-D-M-R-R-I-G-D-G-V-K-V-S-E-R-Y-R-T-T-E-Q-V-E-R-A-Y-V-E-E-R-E-H-T-F-L-Y-A-D-G-E-G-F-H-F-M-N-P-E-T-Y-D-Q-V-A-V-S-E-A-V-V-G-D-A-A-P-Y-L-Q-E-G-M-P-V-Q-V-S-Q-F-N-G-I-A-I-S-L-V-L-P-Q-R-A-T-F-E-V-V-E-T-E-P-T-T-K-G-Q-T-A-S-S-S-Y-K-P-A-V-L-S-N-G-V-R-T-A-V-P-P-H-I-A-P-G-T-R-V-V-V-M-T-A-D-G-S-Y-V-E-R-A-K-D"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-K-S-K-F-R-P-L-H-D-R-V-V-V-R-R-V-E-S-E-S-K-T-A-G-G-I-I-I-P-D-T-A-K-E-K-P-Q-E-G-E-I-I-A-V-G-S-G-A-R-D-E-S-G-K-L-V-P-L-D-V-K-A-G-D-R-I-L-F-G-K-W-S-G-T-E-V-K-L-N-G-E-D-L-L-I-M-K-E-S-D-I-M-G-I-I-G"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-D-T-A-E-R-V-K-K-I-V-I-E-H-L-G-V-D-A-D-K-V-T-E-Q-A-S-F-I-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-F-E-E-E-F-G-V-E-I-P-D-D-A-A-E-T-I-L-T-V-G-D-A-V-K-Y-I-D-K-A-S-A"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-L-Y-E-H-V-F-L-A-R-Q-D-L-S-Q-Q-Q-V-D-A-L-V-E-Q-Y-K-G-V-I-S-A-N-G-G-S-V-G-R-V-E-N-W-G-L-K-S-L-T-Y-R-V-N-K-N-R-K-A-Y-Y-T-L-M-D-L-N-C-P-P-A-A-L-N-E-M-E-R-Q-M-G-L-S-E-D-V-L-R-F-L-T-I-K-V-E-A-H-E-E-G-P-S-A-M-M-Q-K-R-E-E-R-S-E-R-G-S-F-G-D-R-D-R-G-D-R-G-P-R-S-F-G-D-R-D-R-G-D-R-G-D-R-P-P-R-S-F-G-D-A-G-G-D-R-G-P-R-R-P-R-E-G-F-E-G-G-A-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-V-D-I-N-Q-I-P-T-R-R-P-F-H-R-R-R-K-T-C-P-F-S-G-A-N-A-P-K-I-D-Y-K-D-V-R-L-L-Q-R-Y-I-S-E-R-G-K-I-V-P-S-R-I-T-A-V-S-Q-K-K-Q-R-E-L-A-K-A-I-K-R-A-R-F-L-G-L-L-P-Y-V-V-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-V-I-L-L-E-R-V-S-R-L-G-Q-M-G-D-T-V-K-V-K-D-G-F-A-R-N-F-L-L-P-Q-G-K-A-L-R-A-N-E-A-N-K-K-K-F-E-G-Q-R-A-Q-L-E-A-R-N-L-E-R-K-S-E-A-S-Q-V-A-E-K-L-D-G-K-S-F-I-A-V-R-S-A-G-E-T-G-Q-L-Y-G-S-V-S-T-R-D-I-A-E-L-L-T-A-E-G-F-S-V-N-R-N-Q-I-L-L-N-Q-P-I-K-T-I-G-L-T-N-V-A-I-A-L-H-P-E-V-E-V-T-V-T-L-N-I-A-R-T-A-D-E-A-E-R-Q-A-K-G-E-T-L-T-T-A-E-A-I-Y-G-D-D-I-N-D-N-A-R-P-E-N-F-F-D-P-N-A-E-F-D-G-G-E-D-N-A"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-I-G-I-G-S-D-L-I-D-I-R-R-I-E-N-S-L-E-R-H-G-Q-R-F-V-Q-R-I-Y-T-E-V-E-Q-A-R-S-E-N-R-R-A-R-A-A-S-Y-A-K-R-F-A-A-K-E-A-C-A-K-A-L-G-T-G-L-A-Q-G-V-F-W-R-D-M-G-V-V-N-L-P-S-G-A-P-T-M-A-L-T-G-G-A-L-A-R-L-E-K-I-L-P-P-G-H-K-A-A-I-H-L-T-I-T-D-D-F-P-L-A-Q-A-F-V-I-I-E-A-L-P-V-E-Q-A-P-H"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-C-I-D-K-V-D-N-R-F-E-L-V-L-L-A-G-H-R-A-R-Q-I-S-Q-G-A-Q-I-T-V-P-R-D-N-D-K-N-P-V-I-A-L-R-E-I-A-D-E-T-L-S-P-D-D-L-K-E-D-L-I-H-S-L-Q-K-H-V-E-V-D-E-P-E-A-D-G-E-V-I-A-D-Q-T-G-A-A-V-A-A-T-E-T-D-D-A-E-D-N-I-T-F-D-R-M-T-E-E-D-L-L-A-G-I-E-G-L-V-P-P-E-K-S-D-D-Y"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-N-Q-V-R-K-A-D-P-N-N-K-T-V-A-E-N-R-K-A-R-F-S-Y-E-V-L-D-T-I-E-A-G-L-V-L-T-G-T-E-V-K-S-L-R-Q-G-Q-A-N-I-Q-D-S-Y-A-S-V-E-G-G-E-I-W-L-I-N-S-Y-L-P-E-Y-L-Q-A-N-R-F-N-H-E-P-R-R-R-R-K-L-L-L-N-K-R-E-M-A-K-L-S-Q-S-V-D-R-E-G-M-T-L-V-P-L-K-I-Y-F-N-D-Q-G-R-A-K-L-L-L-A-V-G-R-G-K-K-L-H-D-K-R-E-T-E-K-Q-R-D-W-S-R-E-K-G-R-L-L-K-E-R-G"} +{"text": "### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-V-G-M-E-P-L-R-R-K-A-L-I-D-A-T-I-S-A-I-G-E-R-G-S-L-D-V-T-M-S-E-I-A-G-R-A-G-V-S-S-A-L-A-H-H-Y-F-G-A-K-D-E-L-L-F-A-T-M-R-H-I-L-A-E-L-T-I-D-M-R-R-A-L-Q-S-A-K-S-P-R-E-R-V-S-A-V-V-A-V-N-F-S-D-I-Q-F-Q-A-Q-T-I-A-A-W-L-A-F-Y-V-E-A-Q-K-S-S-A-L-R-R-L-L-K-I-Y-A-R-R-L-H-S-N-L-M-S-G-L-T-G-I-L-P-R-A-E-A-D-S-A-A-E-A-T-A-A-M-I-D-G-L-Y-I-R-R-A-L-K-D-G-V-P-N-A-A-T-A-I-A-L-V-E-D-Y-L-E-T-K-L-G-E-R-Q-K-Q"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-G-E-T-N-E-D-V-K-A-M-S-F-E-Q-A-L-D-A-L-E-K-I-V-D-D-L-E-R-G-D-V-P-L-D-Q-S-I-R-I-Y-E-R-G-E-A-L-K-A-H-C-D-R-L-L-K-A-A-E-D-K-V-E-K-I-R-L-S-R-D-G-K-P-V-G-T-E-P-L-D-A-D"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-A-T-S-L-A-T-L-W-A-T-I-A-L-I-I-F-L-G-V-A-I-Y-I-K-V-P-G-L-I-A-K-A-L-D-A-R-A-A-R-I-S-S-E-L-D-E-A-R-K-L-R-D-E-A-Q-Q-L-L-G-Q-Y-K-K-K-R-K-E-A-E-Q-E-A-A-D-I-V-A-A-A-K-R-E-A-E-M-L-A-T-E-A-H-K-K-T-E-D-Y-V-I-R-R-T-A-L-A-E-Q-K-I-G-Q-A-E-R-D-A-V-A-E-V-R-A-S-A-V-D-I-A-V-E-A-A-R-A-L-L-A-A-K-V-D-V-K-A-G-A-D-L-F-K-A-S-L-A-D-V-K-A-K-L-N"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-F-V-T-S-A-F-A-E-E-T-A-P-A-V-T-G-G-D-T-H-S-G-T-G-V-P-A-E-A-H-G-T-F-P-P-F-D-P-A-T-F-P-S-Q-L-L-W-L-A-I-T-F-G-L-F-Y-L-F-L-K-K-V-A-M-P-R-I-G-G-I-I-D-V-R-N-D-R-I-S-Q-D-L-D-Q-A-S-K-L-K-G-E-A-D-A-A-V-A-A-Y-E-Q-E-L-A-E-A-K-K-N-A-S-S-I-G-Q-Q-A-A-D-A-A-K-A-E-A-E-T-A-R-K-K-I-E-A-A-L-D-E-K-L-G-E-A-E-A-R-I-S-S-I-K-A-N-A-M-K-E-V-G-S-I-A-E-D-T-A-S-A-I-V-E-A-L-V-G-G-K-A-S-K-A-E-I-A-A-A-V-K-S-V-A-R"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-N-I-N-T-P-S-Q-F-V-F-L-S-S-A-W-A-D-P-I-E-L-I-N-L-C-T-N-A-L-G-N-Q-F-Q-T-Q-Q-A-R-T-V-V-Q-R-Q-F-S-E-V-W-K-P-S-P-Q-V-T-V-R-F-P-D-S-D-F-K-V-Y-R-F-N-A-V-L-D-P-L-V-T-A-L-L-G-A-F-D-T-R-N-R-I-I-E-V-E-N-Q-A-N-P-S-T-A-E-T-L-D-A-T-R-R-V-D-D-A-T-V-A-I-R-S-A-I-N-N-L-I-V-E-L-T-R-G-T-G-S-Y-N-R-S-S-F-E-S-S-S-G-L-V-W-T-S-S-P-A-T"} +{"text": "### FUNCTION Probable regulatory subunit of the calcium activated potassium KCNMA1 ### SEQUENCE -M-L-A-K-K-L-V-T-A-Q-K-R-G-E-T-R-A-L-C-L-G-L-G-M-V-A-C-S-M-M-M-Y-F-F-I-G-I-T-I-V-P-F-Y-T-K-S-V-W-T-T-E-T-I-C-K-V-L-K-A-N-I-K-D-K-T-H-C-T-N-S-E-G-S-E-D-E-D-I-F-H-Y-P-C-L-Q-V-W-V-N-L-T-A-S-G-Q-E-V-M-L-Y-H-T-E-D-T-L-E-R-N-P-K-C-S-Y-V-P-G-N-S-E-N-S-K-E-V-K-A-R-I-E-T-I-A-S-N-F-K-K-Y-Q-T-F-P-C-Y-Y-D-P-G-G-M-Q-T-N-V-I-L-S-R-L-Y-P-P-K-G-L-L-F-T-F-L-W-P-T-L-M-F-T-G-G-C-L-I-I-V-L-V-K-I-S-Q-Y-F-S-V-L-S-A-R-Q"} +{"text": "### FUNCTION May have a role in the cell cycle ### SEQUENCE -M-S-H-T-I-L-L-V-Q-P-T-K-R-P-E-G-R-T-Y-A-D-Y-E-S-V-N-E-C-M-E-G-V-C-K-M-Y-E-E-H-L-K-R-M-N-P-N-S-P-S-I-T-Y-D-I-S-Q-L-F-D-F-V-D-D-L-A-D-L-S-C-L-V-Y-R-A-D-T-Q-T-Y-Q-P-Y-N-K-D-W-I-K-E-K-I-Y-V-L-L-R-R-Q-A-Q-Q-A-G-K"} +{"text": "### FUNCTION Odorant receptor ### SEQUENCE -V-A-I-C-N-P-L-L-Y-T-I-S-M-P-K-S-L-C-M-K-L-V-A-G-S-Y-L-G-G-V-L-N-S-L-T-Q-T-C-C-L-L-P-L-P-F-C-G-P-N-V-I-N-H-Y-F-C-D-T-N-P-L-L-K-L-T-C-S-D-G-R-L-N-E-L-L-L-V-T-F-N-G-T-I-S-M-T-V-L-L-I-I-V-I-S-Y-V-Y-I-L-V-S-I-L-S-I-R-S-A-R-G-R-H-K-A-F-S-T-C-A-S-H-L-L-T-V-T-L-F-Y-V-P-A-G-L-S-H-M-Q-P-G-S-K-Y-S-L-D-M-E-K-V-T-A-V-F-Y-T-L-L-V"} +{"text": "### FUNCTION Odorant receptor ### SEQUENCE -V-A-I-C-S-P-L-L-Y-S-T-V-M-T-K-R-V-C-M-Q-L-V-V-G-S-Y-M-G-G-L-L-N-S-L-T-H-T-C-G-L-L-G-L-P-F-C-G-P-N-V-I-N-H-Y-F-C-D-I-P-P-L-L-Q-L-A-C-S-D-T-H-R-N-E-T-L-L-L-A-F-S-A-V-I-A-L-F-T-L-F-V-I-T-A-S-Y-M-L-I-L-S-V-I-L-K-I-Q-S-D-D-G-R-K-K-T-F-H-T-C-A-S-H-L-T-A-I-T-I-F-F-G-S"} +{"text": "### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-K-L-V-P-I-A-S-K-T-C-P-A-G-K-N-L-C-Y-K-M-F-M-M-S-D-L-T-V-P-V-K-R-G-C-I-D-V-C-P-K-S-S-L-L-V-K-Y-V-C-C-N-T-D-I-C-N"} +{"text": "### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-K-L-P-P-I-A-S-K-T-C-P-A-G-K-N-L-C-Y-K-M-F-M-M-S-D-L-T-I-P-V-K-R-G-C-I-D-V-C-P-K-N-S-L-L-V-K-Y-V-C-C-N-T-D-R-C-N"} +{"text": "### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-K-L-V-P-L-F-Y-K-T-C-P-A-G-K-N-L-C-Y-K-M-F-M-V-S-N-K-M-V-P-V-K-R-G-C-I-D-V-C-P-K-N-S-A-L-V-K-Y-V-C-C-N-T-D-R-C-N"} +{"text": "### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-Q-L-I-P-P-F-Y-K-T-C-A-A-G-K-N-L-C-Y-K-M-F-M-V-A-A-Q-R-F-P-V-K-R-G-C-I-D-V-C-P-K-S-S-L-L-V-K-Y-V-C-C-N-T-D-R-C-N-N"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-P-K-E-E-V-L-E-F-P-G-V-V-T-E-L-L-P-N-A-M-F-R-V-K-L-E-N-E-H-E-I-I-A-H-T-A-G-R-M-R-K-N-R-I-R-V-L-T-G-D-K-V-L-V-E-M-T-P-Y-D-L-T-K-G-R-I-T-Y-R-F-K"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-N-S-D-S-K-I-T-P-L-R-P-K-R-P-C-P-E-C-G-K-P-S-A-R-D-T-F-P-F-C-S-A-R-C-K-D-I-D-L-N-R-W-L-K-G-A-Y-V-I-K-A-R-D-D-E-E-E-P-D-A-D-E-P-K"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-A-A-L-A-K-F-R-P-V-D-S-G-Q-H-D-K-D-E-L-R-E-I-V-R-E-R-S-F-R-F-G-R-Y-T-L-S-S-G-I-E-S-D-I-Y-F-N-M-K-P-T-M-M-V-A-R-G-A-Q-L-A-A-L-E-F-L-K-I-V-E-Q-V-K-A-E-Y-V-G-G-L-E-M-G-A-V-P-V-I-G-S-M-A-A-V-S-S-M-M-N-K-P-I-N-T-I-F-V-R-K-V-P-K-A-H-G-T-R-D-V-I-E-G-L-G-P-K-E-D-L-E-G-K-V-V-L-I-V-D-D-V-A-T-S-G-K-S-I-L-K-A-I-E-E-V-R-R-V-G-G-I-V-G-D-A-A-C-L-V-D-R-D-E-G-A-T-A-L-L-A-Q-H-G-V-T-L-H-S-V-L-H-A-S-E-F-V-E-R-H"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-R-S-C-F-A-E-S-R-A-I-D-V-T-D-I-L-A-R-L-K-S-L-S-A-A-E-E-F-F-A-V-L-G-I-S-Y-D-P-R-V-L-N-V-S-R-L-H-I-L-K-R-M-G-Q-Y-L-A-E-E-D-F-A-G-L-P-D-G-V-I-A-A-R-A-R-A-T-L-E-R-A-Y-E-D-F-A-T-S-S-P-L-T-H-R-V-F-K-V-L-K-E-H-D-P-D-K-P-A-T-R-D-H-T-F-V-P-F-E-S-I-L-R-R-F-G-T-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-Q-S-N-L-R-P-L-H-D-R-V-V-V-R-R-V-E-S-E-S-K-T-A-G-G-I-I-I-P-D-T-A-K-E-K-P-Q-E-G-E-I-I-A-V-G-S-G-A-R-D-E-A-G-K-L-V-P-L-D-V-K-A-G-D-R-I-L-F-G-K-W-S-G-T-E-V-K-L-N-G-E-D-L-L-I-M-K-E-A-D-I-M-G-I-I-G"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-Q-E-F-I-S-K-G-N-V-M-D-L-A-V-G-V-I-I-G-A-A-F-G-K-I-V-T-S-L-V-D-D-V-I-M-P-I-F-G-A-I-F-G-G-L-D-F-N-N-Y-Y-I-G-L-S-S-A-V-N-A-T-S-L-A-E-A-K-K-Q-G-A-V-F-A-Y-G-S-F-I-T-A-V-L-N-F-L-I-L-A-F-I-I-F-L-M-V-K-A-V-N-N-L-R-R-R-L-E-R-E-K-P-A-A-P-A-A-P-P-P-A-D-V-A-L-L-T-E-I-R-D-L-L-A-K-R"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-S-S-A-K-K-A-T-R-K-I-A-R-R-A-A-I-N-K-N-R-R-S-R-V-R-T-Y-V-R-Q-V-E-E-A-L-A-S-G-D-K-A-A-A-Q-A-A-F-K-A-A-E-P-E-L-M-R-A-A-T-K-G-V-I-H-K-N-T-A-S-R-K-V-S-R-L-A-A-R-L-K-V-L-S-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-I-T-A-E-R-K-K-E-L-M-G-E-F-A-T-A-K-G-D-T-G-S-P-E-V-Q-V-A-I-L-S-E-R-I-K-N-L-T-D-H-F-K-D-H-K-K-D-N-H-S-R-R-G-L-L-A-L-V-S-Q-R-R-S-L-L-D-Y-L-K-R-K-D-D-V-R-Y-Q-T-L-I-E-K-L-G-L-R-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-R-P-T-T-S-S-P-S-Q-R-M-L-R-V-A-E-Q-V-R-H-A-L-S-E-T-L-Q-R-G-E-I-I-D-P-L-I-E-N-T-V-V-S-V-S-E-V-R-M-S-P-D-L-R-V-A-T-A-F-V-S-P-L-G-A-K-D-T-D-A-V-V-E-A-L-N-K-H-A-K-F-V-R-G-R-V-S-G-A-L-R-Q-M-K-F-M-P-E-F-R-F-K-L-D-T-S-F-D-N-F-A-R-I-N-D-L-L-K-S-P-E-V-A-R-D-L-D-A-D-D-D-K-T-K-D-D-R-A-K-D-D-K-D-S-E"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-P-E-D-N-L-S-G-D-G-G-P-P-V-D-I-D-I-S-V-E-A-G-D-W-P-D-E-A-G-L-A-R-L-V-D-R-A-V-D-A-A-F-A-E-T-G-V-T-G-R-S-E-L-S-V-V-F-S-D-D-A-H-I-R-T-L-N-A-E-W-R-G-K-D-K-P-T-N-V-L-S-F-P-A-F-P-F-A-Q-G-G-P-L-P-P-M-L-G-D-I-V-L-A-A-E-T-V-S-R-E-A-A-L-E-D-K-P-V-Q-N-H-I-T-H-L-V-I-H-G-L-L-H-L-L-G-H-D-H-E-T-D-A-E-A-E-A-M-E-A-I-E-R-A-A-L-A-R-L-A-I-P-D-P-Y-A"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-K-D-L-L-G-L-M-G-K-A-K-E-M-Q-A-K-F-Q-A-M-Q-D-E-I-A-T-V-E-S-V-G-Q-A-G-G-G-L-V-S-V-I-L-S-G-K-F-E-M-K-S-L-K-I-D-P-S-L-F-K-E-D-E-V-E-I-L-E-D-L-I-L-A-A-H-N-D-A-K-A-K-V-E-Q-I-M-Q-E-K-T-K-A-L-T-S-G-L-P-I-P-P-G-M-K-L-P-F"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-R-A-A-L-Q-N-S-S-V-I-G-P-T-V-G-F-V-R-L-P-H-A-E-G-L-P-L-P-A-Y-E-S-T-G-A-A-G-M-D-L-R-A-A-V-P-D-D-R-P-L-L-I-L-P-G-K-R-S-L-V-P-T-G-L-I-L-E-I-P-E-G-M-E-G-Q-V-R-P-R-S-G-L-A-F-K-H-G-L-T-V-L-N-S-P-G-T-V-D-S-D-Y-R-G-E-V-K-V-L-L-I-N-L-G-D-E-D-F-A-V-T-R-G-M-R-I-A-Q-I-V-F-A-V-V-T-Q-A-A-V-E-E-R-S-L-A-G-G-T-A-R-G-S-G-G-F-G-S-T-G-T-V"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 5-hydroxyisourate ### SEQUENCE -M-A-E-T-S-K-A-D-G-G-R-L-T-T-H-V-L-D-T-A-T-G-K-P-A-A-G-L-S-I-A-L-Y-R-L-D-G-S-A-R-T-H-L-K-T-V-A-T-N-A-D-G-R-C-D-A-A-L-L-A-G-A-E-F-R-A-G-E-Y-E-L-V-F-A-A-G-D-Y-L-R-G-Q-G-T-K-L-P-E-P-A-F-L-D-S-V-P-I-R-F-G-M-A-E-A-V-H-Y-H-V-P-L-L-I-S-P-Y-G-Y-S-T-Y-R-G-S"} +{"text": "### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate -ureidoglycolate, generating urea and glyoxylate Involved in the utilization of allantoin as nitrogen source ### SEQUENCE -M-T-R-I-T-A-R-P-L-T-R-E-A-F-A-P-F-G-D-V-I-D-M-G-G-D-N-H-Y-P-I-N-G-G-K-A-E-R-Y-H-D-L-A-T-A-E-A-T-G-P-N-A-R-V-L-I-S-M-V-R-G-T-P-Y-E-L-P-L-K-L-T-M-V-E-R-H-P-F-G-S-Q-A-F-I-P-L-S-P-R-P-F-L-V-V-V-C-H-D-G-K-E-G-P-G-E-P-Y-A-F-I-T-A-P-G-Q-G-I-N-Y-S-R-N-L-W-H-G-V-L-T-P-L-G-E-P-Q-D-F-L-I-V-D-R-G-G-D-G-S-N-L-E-E-F-H-F-S-H-A-Y-E-I-H-L-P"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-R-R-P-F-K-A-A-A-P-T-K-D-G-P-R-S-N-R-D-I-R-V-P-R-V-Q-L-I-D-A-E-G-Q-N-R-G-D-V-S-I-N-D-A-L-L-L-A-E-E-A-G-L-D-L-V-E-I-S-P-N-A-V-P-P-V-V-K-I-L-D-L-G-K-L-K-Y-A-N-Q-K-K-A-A-E-A-R-K-N-Q-K-V-I-E-I-K-E-I-K-M-R-P-N-I-D-S-H-D-Y-E-T-K-M-K-A-V-R-R-F-F-E-E-G-D-K-V-K-L-T-L-R-F-R-G-R-E-M-A-H-M-E-L-G-M-Q-L-L-N-K-V-R-E-E-V-A-T-I-A-K-V-E-A-E-P-K-L-E-G-R-Q-M-M-M-V-L-A-P-R"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-T-S-H-A-K-H-K-K-V-L-K-A-A-K-G-F-Y-G-R-R-K-N-T-I-R-I-A-K-Q-A-V-E-K-S-L-Q-Y-A-Y-R-D-R-K-N-R-K-R-S-F-R-A-L-W-I-Q-R-I-N-A-A-T-H-E-H-G-L-T-Y-G-R-F-I-D-G-L-N-K-A-G-I-E-I-D-R-K-I-L-S-D-M-A-I-H-E-P-Q-A-F-A-A-L-V-A-K-A-K-V-A-L-E-Y-L-K-N-T-T-P-N-A-F-E-S-A-V-A"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-K-L-N-L-N-T-D-F-T-K-F-P-R-A-V-S-V-L-A-A-G-E-A-G-A-A-P-A-F-A-K-A-V-L-A-H-D-E-R-H-L-R-R-R-A-V-E-L-T-D-G-S-K-V-L-V-D-L-P-E-P-V-A-L-N-D-G-D-R-L-V-L-E-D-G-R-H-V-E-I-I-A-A-P-E-E-V-Y-D-I-R-A-R-D-G-V-H-L-T-E-L-A-W-H-I-G-N-R-H-L-A-A-G-I-E-A-D-R-I-V-I-L-R-D-H-V-I-K-A-M-L-E-G-L-G-A-T-V-R-E-V-S-E-P-F-K-P-V-R-G-A-Y-S-G-G-H-D-H-G-H-A-H-A-H-S-H-A-E-A-H-S-H-A-H-G-E-S-H-S-H-S-H-S-H-S-H-D-D-H-H-H-H-D-H-D"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-P-I-K-P-L-I-I-L-P-D-P-I-L-R-Q-V-S-K-P-V-E-R-V-D-A-P-L-R-K-L-A-D-D-M-L-A-T-M-Y-D-A-P-G-I-G-L-A-A-I-Q-I-G-E-P-L-R-M-L-V-I-D-L-A-K-E-D-E-T-P-A-P-H-V-F-I-N-P-E-I-L-E-S-A-E-A-R-S-V-Y-E-E-G-C-L-S-I-P-D-Y-Y-A-E-V-E-R-P-A-S-V-R-V-K-Y-L-D-R-D-G-K-L-Q-E-M-E-A-E-G-L-M-A-T-C-L-Q-H-E-I-D-H-L-N-G-V-L-F-I-D-H-I-S-K-L-K-R-D-M-V-V-K-K-F-K-K-L-A-K-D-K-A-P-G-K-L-V-G"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-G-Q-N-P-K-R-L-L-K-R-A-E-F-L-A-V-R-R-G-E-K-R-R-G-R-F-F-L-V-E-V-L-D-R-G-D-G-G-V-P-R-V-G-Y-T-V-T-K-K-V-G-N-A-V-V-R-N-R-V-R-R-R-L-K-E-A-V-R-V-H-A-A-D-D-M-V-P-G-N-D-Y-V-I-V-G-R-D-D-A-L-R-A-P-F-G-Q-L-K-A-E-L-S-R-R-F-R-G-T-R"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-Q-E-F-I-S-K-G-N-V-M-D-L-A-V-G-V-I-I-G-A-A-F-G-K-I-V-D-S-L-V-N-D-I-I-M-P-V-I-G-A-I-F-G-G-L-D-F-N-N-Y-F-V-G-L-S-S-A-V-N-A-T-S-L-A-D-A-K-K-Q-G-A-V-F-A-Y-G-S-F-I-T-V-A-L-N-F-V-I-L-A-F-I-I-F-L-M-V-K-A-V-N-N-L-R-R-R-L-E-R-E-K-P-A-T-P-A-A-P-P-P-A-D-V-A-L-L-T-E-I-R-D-L-L-A-R-R"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-Q-E-F-I-S-K-G-N-V-M-D-L-A-V-G-V-I-I-G-A-A-F-G-K-I-V-D-S-L-V-N-D-I-I-M-P-I-I-G-A-I-F-G-G-L-D-F-N-N-Y-F-V-G-L-S-S-A-V-N-A-T-S-L-A-D-A-R-K-Q-G-A-V-L-A-Y-G-S-F-I-T-V-A-L-N-F-V-I-L-A-F-I-I-F-L-M-V-K-A-V-N-N-L-R-K-R-L-E-R-E-K-P-A-A-A-A-P-P-P-A-D-I-A-L-L-T-Q-I-R-D-L-L-A-R-K"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-A-S-N-D-D-A-P-V-G-A-A-N-G-N-G-N-T-G-A-Q-P-S-L-N-V-L-A-Q-Y-V-K-D-L-S-F-E-S-P-G-A-P-N-S-L-R-G-R-D-K-A-P-G-I-A-I-N-V-N-V-N-A-N-P-L-S-D-K-Q-F-D-V-N-L-T-L-N-A-K-A-S-F-D-Q-E-V-L-F-N-V-E-L-V-Y-G-G-V-F-A-I-S-G-F-P-Q-E-H-M-L-P-I-L-F-I-E-C-P-R-L-L-F-P-F-A-R-Q-I-I-A-E-A-T-R-N-G-G-F-P-P-L-M-L-D-P-I-D-F-A-Q-M-F-Q-Q-K-I-A-E-D-Q-A-A-S-K-V-K-V-S"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-D-E-K-A-A-P-G-S-E-T-A-I-F-A-G-G-C-F-W-G-V-Q-G-V-F-Q-H-V-K-G-V-S-K-A-V-S-G-Y-T-G-G-A-K-D-D-A-V-Y-E-T-V-G-T-G-R-T-G-H-A-E-S-V-E-I-T-Y-D-P-S-K-V-T-Y-G-Q-L-L-Q-V-Y-F-S-V-A-H-N-P-T-Q-L-N-F-Q-G-P-D-S-G-T-Q-Y-R-S-T-I-F-A-E-N-D-T-Q-K-Q-I-A-Q-S-Y-I-D-Q-L-D-K-A-K-L-Y-P-A-P-I-V-T-T-I-E-T-G-K-T-F-Y-P-A-E-N-Y-H-Q-D-F-L-T-L-N-P-T-Y-P-Y-I-V-Y-N-D-L-P-K-V-A-N-L-K-Q-L-F-P-A-L-Y-S-E-K-P-V-L-V-L-S-A-S-N"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-T-E-K-I-I-L-A-S-G-S-P-F-R-K-A-M-L-I-N-A-G-L-D-V-E-A-V-P-A-D-V-D-E-R-A-L-E-A-P-L-Q-D-S-G-V-S-P-E-D-V-A-L-V-L-A-E-A-K-A-T-E-V-S-E-R-R-P-G-A-L-V-L-G-C-D-Q-T-L-S-L-G-D-E-V-F-H-K-P-A-D-M-E-G-A-R-R-H-L-L-A-L-S-G-R-T-H-Q-L-N-S-A-A-V-L-V-R-D-G-K-V-L-W-R-H-V-G-I-A-G-M-T-M-R-M-L-D-P-G-F-I-G-R-H-L-A-L-V-G-A-K-A-L-A-S-V-G-A-Y-Q-I-E-G-E-G-I-Q-L-F-E-K-I-E-G-D-Y-F-T-I-V-G-L-P-L-L-P-L-L-A-E-L-R-T-L-G-A-I-D-G"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-K-P-Q-N-P-V-Q-M-A-V-I-G-A-A-H-G-I-K-G-E-L-R-V-K-T-F-T-G-E-P-M-A-L-A-D-Y-G-P-L-Y-A-R-D-G-R-A-F-Q-I-T-D-I-R-P-A-N-T-V-V-V-V-R-F-K-G-I-S-D-R-N-A-A-E-A-L-A-G-T-E-L-F-V-D-R-S-M-L-P-D-D-G-E-E-D-E-F-Y-H-A-D-L-V-G-L-E-V-R-D-D-T-G-T-A-L-G-K-V-V-A-V-H-N-F-G-G-G-D-I-L-D-V-T-L-A-G-R-K-G-V-L-I-P-F-T-Q-A-A-V-P-D-V-S-V-A-E-G-F-V-R-V-D-P-V-A-A-G-L-V-E-D-E-D-G-D-A-P-R-E-E-D-F-D-P-K-G-R-P-R-G-P-R-D-A-G-G-N-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-Q-S-S-S-P-I-S-G-V-A-E-R-Y-A-G-S-L-F-E-L-A-L-Q-A-N-S-V-A-K-V-E-S-D-L-N-S-F-E-A-M-L-A-G-S-S-D-L-T-R-L-I-N-S-P-V-F-S-G-E-E-Q-A-K-A-I-A-A-I-A-D-K-A-G-I-T-G-L-T-G-N-F-L-R-V-V-A-R-N-R-R-L-F-A-V-P-G-M-I-K-A-F-R-Q-I-A-A-E-H-R-G-E-T-A-A-E-V-T-S-A-H-E-L-T-A-A-Q-Q-T-E-L-K-A-A-L-K-S-V-A-G-K-D-V-A-I-S-V-T-V-D-P-S-L-L-G-G-L-V-V-K-I-G-S-R-Q-I-D-T-S-L-K-T-K-L-N-S-L-K-L-A-L-K-E-V-G"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-E-A-F-K-F-E-L-V-S-P-E-R-L-L-V-S-E-Q-V-E-S-V-V-I-P-G-A-E-G-E-M-T-V-M-A-H-H-A-P-V-M-T-T-I-K-P-G-V-V-T-V-K-T-A-S-G-G-E-E-R-Y-V-V-F-G-G-F-A-D-I-V-P-A-G-C-T-L-L-A-E-S-A-V-A-V-K-D-V-D-R-A-D-L-A-R-R-I-Q-E-A-K-E-D-A-A-D-A-K-D-D-Q-A-R-S-K-A-E-Q-F-L-S-Q-L-T-T-L-E-G-A-I-L-P-A"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-P-H-A-E-K-G-L-T-V-G-L-F-G-G-S-F-N-P-P-H-A-G-H-A-L-V-A-E-I-A-L-R-R-L-A-L-D-Q-L-W-W-M-V-T-P-G-N-P-L-K-S-T-R-E-L-A-P-L-A-E-R-L-Q-L-S-E-Q-I-A-R-N-P-K-I-K-V-T-A-F-E-A-A-H-H-V-R-Y-T-A-D-T-L-A-L-V-K-A-R-N-P-G-V-D-F-V-W-I-M-G-A-D-S-L-R-D-F-H-R-W-Q-R-W-R-E-I-V-L-T-F-P-I-A-V-I-D-R-P-G-A-T-L-S-F-L-S-S-V-V-A-K-T-F-D-Y-A-R-I-D-E-G-D-A-P-L-L-A-R-M-R-A-P-A-W-T-F-I-H-G-P-R-S-S-L-S-S-S-A-I-R-K-M-A-K-G"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-S-V-H-A-V-G-R-M-K-A-G-P-E-R-E-L-A-D-R-Y-F-E-R-F-A-K-S-G-P-A-V-G-L-E-F-A-G-I-T-E-I-A-E-G-R-S-Q-S-A-I-E-R-Q-R-D-E-G-S-R-L-Q-A-Q-L-Q-P-G-T-A-L-I-L-L-D-E-R-G-K-S-L-S-S-Q-D-L-A-N-R-I-G-Q-L-R-D-G-G-R-K-V-L-V-L-A-I-G-G-A-D-G-H-D-P-P-L-R-D-Q-A-D-L-V-L-S-F-G-A-L-T-W-P-H-Q-L-V-R-V-M-L-G-E-Q-L-Y-R-V-A-T-I-L-S-G-H-P-Y-H-R-A"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-P-K-T-K-K-V-D-R-E-T-L-P-Y-R-P-C-V-G-L-M-I-L-N-G-E-G-L-V-W-V-G-H-R-I-A-E-P-D-S-E-F-A-G-T-T-Q-L-W-Q-M-P-Q-G-G-I-D-K-G-E-E-P-L-Q-A-A-E-R-E-L-Y-E-E-T-G-M-R-S-V-S-L-L-A-E-A-P-D-W-I-N-Y-D-L-P-D-H-L-V-G-I-A-F-K-G-R-Y-R-G-Q-M-Q-K-W-F-A-F-R-F-H-G-D-G-S-E-I-Q-I-N-P-P-P-G-G-H-T-A-E-F-D-K-W-S-W-R-P-M-Q-D-L-P-D-L-I-V-P-F-K-R-K-V-Y-E-E-V-V-A-A-F-S-H-L-A-R"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-S-A-I-H-P-D-Y-H-T-I-K-V-V-M-T-D-G-T-E-Y-T-T-R-S-T-W-G-K-E-G-D-T-M-N-L-D-I-D-P-T-T-H-P-A-W-T-G-G-Q-Q-T-L-L-D-R-G-G-R-L-S-K-F-K-K-R-F-E-G-F-G-L"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-K-I-N-G-N-E-I-R-P-G-Y-V-I-E-H-D-G-G-L-W-V-A-V-R-T-N-T-V-K-P-G-K-G-G-A-Y-N-Q-V-E-L-K-N-L-I-N-G-T-K-L-N-E-R-F-R-S-A-E-T-V-E-Q-I-R-L-D-L-K-D-F-S-F-L-Y-E-Q-D-D-A-L-V-F-M-D-T-Q-S-Y-E-Q-L-E-L-N-K-D-F-V-G-D-R-A-A-F-L-Q-D-G-M-M-V-T-V-Q-L-Y-E-E-R-P-I-G-I-S-L-P-D-Q-V-T-L-T-I-T-E-A-D-P-V-V-K-G-Q-T-A-A-A-S-Y-K-P-A-V-L-K-N-G-I-R-V-L-V-P-P-F-I-G-A-G-E-R-I-I-V-D-T-N-E-I-T-Y-V-R-R-A-D"} +{"text": "### FUNCTION Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity ### SEQUENCE -M-G-R-I-A-A-L-T-R-N-P-V-M-I-A-L-V-A-M-L-A-I-A-G-C-A-S-K-K-T-P-N-N-A-A-D-L-G-L-N-G-A-G-A-A-T-P-G-S-A-Q-D-F-T-V-N-I-G-D-R-I-F-F-D-T-D-S-S-S-I-R-A-D-A-Q-T-T-L-A-R-Q-A-Q-W-L-N-Q-Y-K-Q-Y-A-I-V-V-E-G-H-A-D-E-R-G-T-R-E-Y-N-L-A-L-G-A-R-R-A-A-A-A-R-D-F-L-V-S-K-G-V-A-S-S-R-L-K-T-I-S-Y-G-K-E-R-P-V-A-V-C-D-D-I-S-C-W-S-Q-N-R-R-A-V-T-T-L-S-G-A-G-S"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-I-K-S-E-L-V-Q-I-I-A-T-R-N-P-H-L-F-L-R-D-V-E-N-I-V-G-A-I-F-D-E-I-T-D-A-L-A-E-G-N-R-V-E-L-R-G-F-G-A-F-S-V-K-N-R-P-A-R-T-G-R-N-P-R-T-G-E-S-V-E-V-E-E-K-W-V-P-F-F-K-T-G-K-E-L-R-E-R-L-N-G-G-K"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-L-K-Q-I-R-P-A-I-V-M-I-V-F-F-T-V-L-T-G-L-V-Y-P-L-G-M-T-G-I-A-Q-A-L-F-P-R-Q-A-N-G-S-L-I-E-K-D-G-K-V-I-G-S-E-L-I-G-Q-A-F-A-S-D-K-Y-F-H-G-R-P-S-A-A-G-N-G-Y-D-A-G-A-S-G-G-S-N-L-G-P-T-N-P-K-L-I-E-R-I-K-G-G-A-E-K-L-K-A-E-N-P-N-Q-P-V-P-M-D-L-V-T-T-S-G-S-G-L-D-P-Q-I-S-P-E-A-A-Y-F-Q-V-P-R-V-A-K-A-R-G-I-D-E-A-K-V-K-A-L-V-D-G-Q-V-E-G-R-E-L-G-F-M-G-E-P-V-V-N-V-L-A-L-N-L-A-L-D-A-A-K"} +{"text": "### FUNCTION Has a post-transcriptional repressor function in flagellum biogenesis Associates with the 5'-UTR of fljK mRNA and promotes its degradation ### SEQUENCE -M-T-N-T-L-K-I-S-L-K-P-N-E-K-I-Y-I-N-G-A-V-I-R-V-D-R-K-V-T-I-E-L-M-N-D-V-Q-F-L-L-E-S-H-V-I-Q-A-D-Q-A-S-T-P-L-R-Q-L-Y-F-I-V-Q-V-M-L-I-N-P-A-G-A-D-D-A-R-E-M-F-R-R-S-L-P-L-L-I-A-S-F-E-D-A-E-I-C-S-A-L-K-Q-I-D-R-M-V-G-E-D-H-I-Y-E-A-L-K-A-I-R-S-L-Y-P-L-E-R-R-A-L-G-G-N-D-D-V-P-G-A-P-R-P-L-A-V-G-A-R-Y"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-P-E-I-T-T-K-P-R-T-K-V-K-P-Q-T-E-R-P-K-L-Y-K-V-I-L-I-N-D-D-F-T-P-R-E-F-V-V-T-V-L-K-G-E-F-K-L-S-E-D-Q-A-H-R-I-M-I-T-A-H-R-R-G-V-C-V-V-A-V-F-T-K-D-V-A-E-T-K-A-T-R-A-T-D-A-G-K-A-K-G-Y-P-L-L-F-T-T-E-P-E-E"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-K-P-S-L-E-D-T-L-L-A-S-I-R-T-I-P-D-Y-P-K-P-G-I-L-F-R-D-I-T-T-L-L-G-N-A-R-A-F-R-R-A-I-D-E-L-V-H-P-Y-A-G-Q-K-V-D-K-I-A-G-I-E-A-R-G-F-I-L-G-G-A-V-A-H-Q-L-S-A-G-F-V-P-I-R-K-K-G-K-L-P-F-D-T-V-R-V-A-Y-S-L-E-Y-G-L-D-E-M-E-M-H-K-D-G-V-A-P-G-E-K-V-I-L-V-D-D-L-I-A-T-G-G-T-A-E-A-A-V-K-L-L-R-Q-I-G-A-D-I-L-A-A-C-F-V-I-D-L-P-D-L-G-G-R-A-K-L-E-A-L-G-V-P-V-R-T-L-I-G-F-E-G-H"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-N-K-V-P-M-T-G-E-G-F-A-S-L-K-E-E-L-R-W-R-Q-Q-E-E-R-P-R-I-I-E-A-I-S-E-A-R-S-H-G-D-L-S-E-N-A-E-Y-H-A-A-K-E-A-Q-S-L-N-E-G-R-V-N-E-L-E-D-L-I-A-R-A-E-V-I-D-V-T-K-L-S-G-D-K-V-K-F-G-A-T-V-V-L-V-D-E-D-T-E-E-K-K-T-Y-Q-I-V-G-D-Q-E-A-D-V-K-S-G-R-I-S-I-S-S-P-I-A-R-A-L-I-G-K-E-V-G-D-A-I-E-V-N-A-P-G-G-A-R-G-Y-E-I-V-Q-V-Q-F-I"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-T-F-R-P-L-H-D-R-I-L-V-R-R-I-E-A-E-E-K-T-A-G-G-I-I-I-P-D-T-A-K-E-K-P-Q-E-G-E-V-I-A-I-G-P-G-A-R-D-E-S-G-K-L-T-P-L-D-V-K-A-G-D-R-I-L-F-G-K-W-S-G-T-E-I-K-L-N-G-E-D-L-L-I-M-K-E-S-D-V-M-G-V-I-E-Q-T-A-T-V-K-K-A-A"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-F-R-P-L-H-D-R-V-V-I-R-R-A-E-G-D-T-K-S-K-G-G-I-I-I-P-D-N-A-K-E-K-P-Q-E-G-E-V-I-A-V-G-P-G-A-R-D-E-N-G-A-L-V-P-L-D-V-K-A-G-D-L-I-L-F-G-K-W-S-G-T-E-V-K-I-D-G-E-D-L-L-I-M-K-E-A-D-I-M-G-V-I-D-K-S-V-E-A-K-K-A-A"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-A-T-S-T-E-R-A-V-L-A-G-G-C-F-W-G-M-Q-D-L-I-R-R-Y-P-G-V-I-S-T-R-V-G-Y-S-G-G-D-V-A-N-A-T-Y-R-N-H-G-T-H-A-E-A-I-E-I-N-F-D-P-A-V-I-S-Y-R-T-L-L-E-R-F-F-Q-I-H-D-P-T-T-R-N-R-Q-G-N-D-V-G-M-S-Y-R-S-A-I-Y-Y-T-S-D-E-Q-K-R-V-A-E-D-T-I-A-D-V-D-A-S-G-L-W-P-G-K-V-V-T-E-V-A-P-A-G-A-F-W-E-A-E-P-E-H-Q-D-Y-L-E-K-Y-P-N-G-Y-T-C-H-F-V-R-P-G-W-K-L-P-V-R-E-K-A-V-S"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis Is involved in the transfer of long hydroxylated fatty acids to lipid A ### SEQUENCE -M-S-T-T-F-D-K-V-A-K-I-I-A-D-T-S-E-I-D-I-D-T-I-T-P-E-S-H-T-I-D-D-L-G-I-D-S-L-D-F-L-D-I-V-F-A-I-D-K-E-F-G-I-K-V-P-L-E-K-W-T-Q-E-V-N-D-G-K-A-S-T-D-D-Y-F-V-M-K-N-L-C-A-K-I-D-A-L-V-A-A-K-T-A"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-I-W-H-W-M-I-V-L-V-I-V-L-L-V-F-G-R-G-K-I-P-E-L-M-G-D-M-A-K-G-I-K-S-F-K-K-G-M-A-D-D-D-V-A-D-D-K-R-T-V-E-H-R-A-D-E-T-V-S-A-V-K-E-K-A-S-K-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-H-D-P-H-G-H-A-H-T-V-R-P-P-G-R-G-R-N-W-P-G-P-W-R-K-T-P-G-R-L-L-G-T-S-F-V-R-L-Y-Q-L-T-L-S-G-F-V-G-N-S-C-R-H-L-P-T-C-S-E-Y-A-H-E-A-I-A-R-H-G-L-W-A-G-G-W-M-G-F-F-R-V-L-R-C-G-P-F-G-T-H-G-I-D-L-V-P-E-V-L-A-D-R-Y-V-W-F-M-P-W-R-Y-W-R-I-G-R-K-R-A-E-T-R-A"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-N-L-M-A-K-T-Y-F-T-S-D-H-E-W-L-R-V-E-G-G-I-A-T-V-G-I-T-D-Y-A-Q-E-Q-L-G-D-L-V-F-V-E-L-P-E-T-G-K-K-L-T-K-G-D-T-A-V-V-V-E-S-V-K-A-A-S-D-V-Y-A-P-V-D-G-E-I-T-E-A-N-G-T-L-S-S-D-P-S-L-V-N-S-A-A-T-G-A-G-W-L-W-K-M-R-L-A-D-E-S-Q-L-A-G-L-M-D-E-A-A-Y-K-A-H-I-A"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-V-N-K-V-I-L-V-G-N-L-G-A-D-P-E-I-R-R-L-N-S-G-E-P-V-V-N-I-R-I-A-T-S-E-S-W-R-D-K-N-S-G-E-R-K-E-K-T-E-W-H-N-V-V-I-F-N-E-G-I-A-K-V-A-E-Q-Y-L-K-K-G-M-K-V-Y-V-E-G-Q-L-Q-T-R-K-W-Q-D-Q-T-G-A-D-K-Y-T-T-E-V-V-L-Q-R-F-R-G-E-L-Q-M-L-D-G-R-Q-G-E-G-G-Q-V-G-G-Y-S-G-G-G-S-S-R-G-S-D-F-G-Q-S-G-P-N-E-S-F-N-R-G-G-G-A-P-R-G-G-G-G-G-G-S-S-R-E-L-D-D-E-I-P-F"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-A-W-L-A-D-G-R-T-L-A-G-L-D-L-G-D-K-T-I-G-V-A-V-S-D-R-G-F-A-F-A-H-P-R-P-V-I-M-R-R-K-F-S-L-D-A-A-V-L-L-A-L-L-K-K-E-N-V-G-A-V-A-I-G-L-P-I-N-M-D-G-S-E-G-P-R-A-Q-K-S-R-A-F-V-R-N-M-A-Q-L-S-D-L-P-F-V-F-W-D-E-R-L-S-T-V-A-A-E-R-T-L-I-E-M-D-F-S-R-A-K-R-A-G-K-I-D-S-A-A-A-A-F-I-L-Q-G-V-L-D-R-L-Q-S-L-D-S-A-A-R-T-E-L-G-G-R-T-E-P-G-P-T-D-A-A"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-V-D-L-Q-T-V-K-R-V-A-R-L-A-R-I-A-V-S-E-E-D-A-E-R-M-T-G-E-L-N-A-I-L-G-F-V-E-Q-L-N-E-V-D-V-S-G-V-E-P-M-T-S-V-T-P-M-E-M-K-K-R-Q-D-V-V-T-D-G-N-K-A-A-D-I-V-A-N-A-P-A-T-E-E-N-F-F-L-V-P-K-V-V-E"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-Q-N-G-G-G-D-G-N-E-A-G-R-G-T-A-V-I-T-R-T-K-T-K-T-K-K-P-S-L-Y-R-V-L-I-L-N-D-D-Y-T-P-M-E-F-V-V-H-V-L-E-R-F-F-Q-K-D-R-E-A-A-T-R-I-M-L-H-V-H-N-H-G-V-G-E-C-G-V-Y-T-F-E-V-A-E-T-K-V-S-Q-V-M-D-F-A-R-Q-N-Q-H-P-L-Q-C-V-M-E-K-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-G-E-Y-D-D-L-K-R-R-M-D-G-A-I-A-A-F-K-H-D-L-A-S-L-R-T-G-R-A-S-S-N-L-L-D-A-I-Q-V-Q-A-Y-G-T-T-M-P-I-N-Q-V-A-N-V-T-V-P-E-P-R-M-I-S-V-S-I-W-D-K-S-M-V-G-A-V-D-R-A-I-R-E-S-N-L-G-F-N-P-I-V-D-G-T-N-L-R-I-P-L-P-E-L-N-E-Q-R-R-K-E-L-V-K-I-S-H-G-Y-A-E-N-A-R-V-A-A-R-H-V-R-R-D-G-M-D-F-L-K-K-A-E-K-D-G-V-I-S-E-D-D-Q-R-K-R-S-D-Q-V-Q-K-L-T-D-E-T-I-S-T-I-D-H-L-L-S-D-K-E-A-E-I-M-Q-V"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-V-A-A-T-T-L-E-A-V-D-I-M-G-L-M-K-L-L-P-H-R-Y-P-F-L-M-I-D-R-I-I-D-I-D-G-D-D-S-A-I-G-I-K-N-V-T-I-N-E-P-H-F-Q-G-H-F-P-E-Q-P-V-M-P-G-V-L-I-V-E-A-M-A-Q-T-A-G-A-I-C-I-R-S-L-G-A-S-K-P-S-L-V-Y-F-L-T-I-D-N-A-K-F-R-K-P-V-V-P-G-D-Q-L-K-I-H-V-K-K-I-K-K-R-G-N-L-L-K-F-A-C-E-A-L-V-D-G-T-K-A-A-E-A-E-I-S-A-M-M-V-T-G-D"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-E-R-S-Q-N-L-Q-D-L-F-L-N-S-V-R-K-S-K-N-P-L-T-I-F-L-I-N-G-V-K-L-T-G-V-V-T-S-F-D-N-F-C-V-L-L-R-R-D-G-H-S-Q-L-V-Y-K-H-A-I-S-T-I-M-P-S-Q-P-V-Q-M-F-D-G-E-E-S-Q-G-A"} +{"text": "### FUNCTION In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP P-II-UMP allows the deadenylation of glutamine synthetase ### SEQUENCE -M-K-K-I-E-A-I-I-K-P-F-K-L-D-E-V-K-E-A-L-Q-E-A-G-L-Q-G-I-T-V-T-E-A-K-G-F-G-R-Q-K-G-H-T-E-L-Y-R-G-A-E-Y-V-V-D-F-L-P-K-V-K-I-E-V-V-L-G-D-D-A-V-E-G-A-I-E-A-I-R-K-A-A-Q-T-G-R-I-G-D-G-K-I-F-V-S-N-I-E-E-V-V-R-I-R-T-G-E-T-G-M-D-A-V"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-F-N-L-L-L-V-V-V-G-G-G-I-G-A-G-I-R-H-L-T-N-M-G-A-L-R-L-V-G-P-N-Y-P-W-G-T-M-A-I-N-I-V-G-S-F-A-M-G-L-F-I-A-I-L-A-R-R-G-G-S-N-E-V-R-L-F-V-A-T-G-I-F-G-G-F-T-T-F-S-A-F-S-L-D-F-A-T-L-W-E-R-G-A-T-L-P-A-F-G-Y-A-L-A-S-V-I-G-A-I-I-A-L-F-L-G-L-W-L-A-R-S-L-P"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-E-A-A-R-V-R-R-R-E-R-K-N-I-S-S-G-V-A-H-V-N-S-T-F-N-N-T-M-I-T-I-T-D-A-Q-G-N-S-I-A-W-S-S-A-G-A-Q-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-D-V-A-K-K-A-Q-E-H-G-M-R-M-L-E-V-E-V-C-G-P-G-S-G-R-E-S-A-L-R-A-L-Q-A-A-G-F-T-I-T-S-I-R-D-V-T-P-I-P-H-N-G-C-R-P-R-K-K-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-T-N-K-R-V-V-I-A-L-Q-Y-I-H-G-I-G-K-K-F-A-Q-E-I-V-D-K-V-G-I-P-A-E-R-R-V-N-Q-L-T-D-A-E-V-L-Q-I-R-E-T-I-D-R-D-Y-Q-V-E-G-D-L-R-R-E-V-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-S-L-P-V-R-G-Q-R-T-H-T-N-A-R-T-R-K-G-P-A-K-S-I-A-G-K-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-D-L-R-D-K-D-G-A-T-H-S-K-K-R-L-G-R-G-I-G-S-G-S-G-K-T-A-G-R-G-V-K-G-Q-K-A-R-S-G-V-A-I-N-G-F-E-G-G-Q-M-P-L-Y-R-R-L-P-K-R-G-F-N-N-I-F-A-K-S-F-V-V-V-S-L-A-R-I-Q-E-A-V-D-A-K-K-L-D-A-K-A-T-V-T-A-E-A-L-V-A-A-G-V-I-R-R-V-K-D-G-V-R-V-L-S-D-G-E-L-K-A-K-L-A-F-D-V-A-G-A-S-K-A-A-I-E-K-I-E-K-A-G-G-S-V-K-L-P-E-K-A-A-A-E"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-Q-E-R-R-E-G-G-R-G-R-E-R-E-E-R-D-D-G-M-V-D-K-L-V-H-I-N-R-V-A-K-V-V-K-G-G-R-R-F-G-F-A-A-L-V-V-V-G-D-Q-K-G-R-V-G-F-G-H-G-K-A-R-E-V-P-E-A-I-R-K-A-T-E-S-A-K-R-D-M-I-F-V-P-L-R-S-G-R-T-L-H-H-D-V-E-G-R-W-G-A-G-R-V-L-L-R-A-A-K-Q-G-T-G-I-I-A-G-G-P-M-R-A-V-F-E-T-L-G-M-H-D-V-V-A-K-S-M-G-S-S-N-P-Y-N-M-V-R-A-T-F-D-A-L-K-S-Q-M-H-P-K-D-V-A-A-A-R-G-I-K-Y-S-T-L-Q-A-R-R-G-T-A-V-A-A-E-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-G-T-K-E-S-T-Q-R-R-A-Q-R-V-R-R-Q-I-R-K-V-A-G-E-R-P-R-L-S-V-H-R-T-S-K-N-I-Y-V-Q-V-I-D-D-A-K-G-H-T-I-A-A-A-S-T-L-E-K-D-L-K-G-S-L-K-T-G-A-D-T-A-A-A-A-A-I-G-K-L-I-A-E-R-A-T-K-A-G-V-K-E-V-V-F-D-R-G-P-Y-I-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-G-G-L-S-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-P-V-S-L-P-Q-G-V-T-A-T-V-N-G-Q-T-V-T-A-K-G-P-K-G-E-L-K-F-V-V-N-D-E-V-L-V-K-M-E-G-S-E-I-A-V-Q-P-R-D-Q-T-K-T-A-R-S-K-W-G-M-S-R-T-Q-I-V-N-I-L-H-G-V-K-D-G-F-E-K-K-L-E-I-T-G-V-G-Y-R-A-A-M-Q-G-K-N-L-Q-L-A-L-G-F-S-H-D-V-V-Y-E-T-P-A-G-V-T-I-A-V-P-K-P-T-E-I-T-V-T-G-I-D-K-Q-Q-V-G-Q-V-A-A-E-I-R-E-Y-R-G-P-E-P-Y-K-G-K-G-V-R-Y-A-G-E-K-I-V-R-K-E-G-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-L-S-D-P-L-G-D-M-L-T-R-I-R-N-A-Y-G-R-K-K-S-S-V-S-T-P-A-S-R-L-R-T-R-V-L-D-V-L-K-A-E-G-Y-I-R-D-Y-S-Q-T-D-F-D-N-G-K-S-E-I-E-I-E-L-K-Y-F-D-G-A-P-V-V-R-E-I-A-R-V-S-K-P-G-R-R-V-Y-V-S-A-K-S-I-P-H-V-A-N-G-L-G-I-A-I-L-S-T-P-K-G-V-M-A-D-H-E-A-R-E-Q-N-V-G-G-E-I-L-C-Q-I-F"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-S-S-V-E-K-N-N-R-R-R-K-L-A-D-Q-Y-G-P-K-R-A-A-L-K-A-I-I-M-D-Q-S-K-P-M-E-E-R-F-R-A-Q-L-K-L-A-A-L-P-R-N-S-A-K-I-R-I-R-N-R-C-E-V-T-G-R-P-R-A-Y-Y-R-K-L-K-V-S-R-I-A-L-R-D-L-G-N-N-G-Q-I-P-G-L-V-K-S-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-A-Q-S-K-Q-A-T-A-T-N-T-P-R-L-K-Q-V-Y-N-E-T-I-R-K-A-L-Q-E-Q-F-G-Y-D-N-D-M-Q-V-P-R-L-D-K-I-V-L-N-M-G-V-G-E-A-T-A-D-S-K-K-P-S-V-A-A-E-D-L-A-L-I-A-G-Q-K-A-V-V-T-R-A-R-N-S-I-A-G-F-K-V-R-E-N-M-P-I-G-A-K-V-T-L-R-K-E-R-M-Y-E-F-L-D-R-L-V-N-I-A-L-P-R-V-R-D-F-R-G-L-N-P-K-S-F-D-G-R-G-N-Y-A-M-G-I-K-E-H-I-V-F-P-E-I-N-Y-D-K-V-D-Q-I-W-G-M-D-V-I-V-C-T-T-A-K-T-D-D-E-A-R-A-L-L-K-A-F-N-F-P-F-R-Q"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-K-I-R-K-G-D-K-V-V-V-L-A-G-K-D-K-G-R-S-G-E-V-L-S-V-Q-P-K-D-D-T-A-L-V-R-G-V-N-M-I-R-R-H-Q-K-Q-S-Q-S-Q-E-G-G-I-I-T-K-E-A-P-I-Q-L-S-N-I-A-L-A-D-P-K-D-G-K-P-T-R-V-G-F-I-F-Q-K-D-G-K-K-V-R-V-A-K-R-S-G-E-V-I-N-G"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-N-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-K-Y-A-S-V-G-D-I-I-V-V-S-I-K-E-A-I-P-R-G-R-V-K-K-G-D-V-M-K-A-V-V-V-R-T-A-K-D-I-R-R-P-D-G-S-V-I-R-F-D-K-N-A-A-V-L-V-D-N-K-K-E-P-I-G-T-R-I-F-G-P-V-P-R-E-L-R-A-K-N-H-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-I-L-Q-G-T-V-V-S-D-K-N-E-K-T-V-V-V-K-V-E-R-R-F-T-H-P-V-M-K-K-T-V-R-M-T-K-K-Y-K-A-H-D-E-N-N-A-H-K-V-G-D-Q-V-F-I-Q-E-S-K-P-I-S-K-D-K-R-W-I-V-V-S-S-D-Q-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-Q-F-K-G-R-I-H-G-T-A-K-G-G-T-N-L-D-F-G-G-F-G-L-K-A-L-E-P-N-R-V-T-A-R-E-I-E-A-A-R-R-A-I-T-R-E-M-K-R-A-G-R-V-W-I-R-I-F-P-D-L-P-V-T-S-K-P-T-E-V-R-M-G-K-G-K-G-A-V-D-Y-W-A-A-R-V-K-P-G-R-I-M-F-E-I-D-G-V-S-E-E-T-A-R-E-A-L-R-L-G-A-A-K-L-S-V-R-T-R-F-V-Q-R-I-A-E"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-G-K-A-K-A-P-R-R-L-A-D-N-E-A-R-A-V-L-R-T-I-R-I-S-P-Q-K-L-N-L-V-A-A-L-I-R-G-K-K-V-A-T-A-L-S-D-L-E-F-S-A-K-R-I-S-G-T-V-K-K-T-L-E-S-A-I-A-N-A-E-N-N-H-D-L-D-V-D-A-L-V-V-A-E-A-Y-V-G-K-S-I-V-M-K-R-F-H-A-R-G-R-G-R-A-S-R-I-E-K-P-F-S-H-L-T-I-V-V-R-E-V-E-E-K-G-E-A-A"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-I-W-K-G-P-F-I-D-G-Y-L-L-K-K-V-D-K-V-R-E-G-G-R-N-E-V-I-K-M-W-S-R-R-S-T-I-L-P-Q-F-V-G-F-T-F-G-V-Y-N-G-Q-K-H-V-P-V-S-V-N-E-D-M-V-G-H-K-F-G-E-F-A-P-T-R-T-Y-Y-G-H-G-A-D-K-K-A-K-R-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-D-L-R-H-Y-D-V-I-V-S-P-A-I-T-E-K-S-T-M-A-S-E-Q-N-Q-V-V-F-N-V-A-K-K-A-S-K-P-E-I-K-A-A-V-E-A-L-F-G-V-K-V-M-A-V-N-T-L-V-R-K-G-K-I-K-R-F-R-G-T-I-G-R-Q-S-D-V-K-K-A-I-V-T-L-A-D-G-Q-S-I-D-V-A-T-G-L"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-N-G-Q-N-I-R-I-R-L-K-A-F-D-H-R-V-L-D-A-S-T-K-E-I-V-S-T-A-K-R-T-G-A-N-V-R-G-P-I-P-L-P-T-R-I-E-K-F-T-V-N-R-S-P-H-V-D-K-K-S-R-E-Q-F-E-M-R-T-H-K-R-L-L-D-I-V-D-P-T-P-Q-T-V-D-A-L-M-K-L-D-L-A-A-G-V-D-V-E-I-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-S-A-E-K-R-E-I-N-P-D-P-K-F-G-D-L-I-V-T-K-F-M-N-A-V-M-Y-D-G-K-K-S-V-A-E-T-I-V-Y-G-A-L-D-Q-V-Q-S-K-T-K-Q-E-P-V-T-V-F-H-Q-A-L-D-N-V-A-P-H-V-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-D-V-R-P-E-R-R-Q-A-L-A-I-R-W-L-I-A-A-A-R-N-R-N-E-T-T-M-I-D-R-L-S-G-E-L-M-D-A-A-N-N-R-G-T-A-V-K-K-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-V-N-Q-L-I-R-K-P-R-I-A-P-V-K-R-N-K-V-P-A-M-Q-Q-N-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-I-R-L-T-N-G-F-E-V-I-G-Y-I-P-G-E-G-H-N-L-Q-E-H-S-V-V-M-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-I-R-G-V-L-D-T-Q-G-V-K-N-R-K-Q-R-R-S-K-Y-G-A-K-R-P-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-D-L-A-K-I-V-D-D-L-S-K-L-T-V-L-E-A-A-E-L-S-K-L-L-E-E-K-W-G-V-S-A-A-A-P-V-A-V-A-A-A-G-G-A-A-A-A-A-A-P-A-E-E-K-T-E-F-D-V-V-L-T-D-A-G-A-Q-K-I-N-V-I-K-E-V-R-A-I-T-G-L-G-L-K-E-A-K-D-L-V-E-A-A-P-K-P-V-K-E-G-V-S-K-A-D-A-D-K-F-K-A-Q-L-E-A-A-G-A-K-V-D-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-D-R-A-E-K-R-E-L-V-T-G-L-N-E-A-F-G-N-A-G-S-V-V-V-A-H-Y-A-G-I-T-V-A-Q-M-N-D-L-R-S-K-M-R-A-A-G-G-T-V-K-V-A-K-N-R-L-A-K-I-A-L-Q-G-T-D-S-A-S-I-I-D-L-F-K-G-Q-T-L-I-A-Y-S-E-D-P-I-A-A-P-K-V-A-S-D-F-A-K-G-N-D-K-L-V-I-L-G-G-A-M-G-T-T-S-L-N-A-D-G-V-K-A-L-A-T-L-P-S-L-D-E-L-R-A-K-L-V-G-M-I-A-T-P-A-T-R-I-A-Q-I-V-N-A-P-A-A-S-V-A-R-V-I-G-A-Y-A-R-K-D-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-A-G-Q-L-K-L-Q-V-S-A-G-S-A-T-P-S-P-P-I-G-P-A-L-G-Q-R-G-I-N-I-M-E-F-C-K-A-F-N-A-Q-T-Q-E-M-E-K-G-S-P-V-P-V-V-I-T-Y-Y-Q-D-K-S-F-T-F-V-M-K-T-P-P-V-S-Y-F-L-K-K-A-A-N-L-K-S-G-S-K-E-P-G-K-V-K-A-G-T-V-S-R-D-K-V-R-E-I-A-T-A-K-M-K-D-L-N-A-N-D-V-E-A-A-M-R-M-V-E-G-S-A-R-S-M-G-L-E-V-V-G"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-V-G-L-G-N-P-G-D-E-Y-D-K-T-R-H-N-L-G-F-M-V-I-D-K-I-A-E-K-L-N-V-K-L-D-K-E-K-F-N-G-I-F-Y-K-G-E-N-Y-I-I-S-K-P-L-T-Y-M-N-N-S-G-N-F-V-Y-D-I-K-N-F-F-D-I-E-I-D-N-I-I-I-I-Y-D-E-I-D-L-K-V-G-Q-A-S-I-K-I-K-G-S-A-N-G-Q-R-G-M-Q-S-I-I-E-K-L-K-T-E-N-I-K-R-I-K-I-G-V-S-R-P-L-Y-E-P-V-S-S-Y-I-L-K-K-I-P-E-N-E-K-E-T-F-E-K-V-I-D-E-L-A-D-K-L-L-T-Y-I-F-N-D-F-K-T-F-I-N-V-S-K-L-K-N-S-K-K"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-Q-K-E-I-F-I-A-G-G-C-F-W-G-V-E-R-Y-F-Q-K-V-K-G-V-L-D-T-K-A-C-Y-I-N-G-G-F-E-G-V-K-Y-K-E-V-C-E-G-S-S-H-V-E-A-V-R-V-I-Y-D-N-S-K-I-T-E-E-D-L-W-K-L-Y-L-R-I-I-N-P-Y-S-L-N-K-Q-G-N-D-R-G-V-Q-Y-R-I-G-L-Y-S-Y-D-K-D-L-L-K-K-F-S-D-L-N-E-A-F-M-K-S-E-G-K-K-N-Y-I-E-I-Q-K-V-E-D-V-T-L-A-E-E-Y-H-Q-N-Y-L-L-K-N-V-N-G-Y-C-H-I-N-L-D-D-I-P-E-E-Y-Q-K-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-S-R-D-R-S-S-L-F-K-K-S-R-R-L-G-F-S-V-L-E-N-E-K-E-F-N-K-G-K-K-R-N-Y-A-P-G-Q-H-G-Q-R-R-T-K-L-S-D-Y-G-L-H-L-Y-E-K-Q-K-V-K-N-L-Y-G-V-N-E-R-Q-F-A-N-S-F-K-K-S-S-K-L-K-G-V-Q-G-T-N-F-L-Q-F-L-E-Q-R-L-D-N-L-V-Y-R-A-G-F-A-E-T-R-R-Q-A-R-Q-F-V-N-H-G-H-V-L-V-D-G-K-K-V-D-I-P-S-Y-R-V-A-V-G-K-V-I-E-I-K-E-K-L-Q-K-N-A-Q-V-L-R-N-K-E-I-R-T-A-A-D-W-L-S-V-K-D-F-K-A-T-F-T-R-L-P-E-R-N-E-F-L-K-E-V-N-D-S-L-I-V-E-F-Y-N-K"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-E-T-L-L-W-K-D-A-R-E-K-I-K-K-G-V-N-F-V-E-F-A-A-P-W-C-P-D-C-V-M-M-K-P-V-I-E-Q-V-E-Q-E-I-K-N-L-N-L-P-V-N-F-Y-H-V-N-A-D-E-S-G-M-F-R-K-A-D-A-E-V-A-V-L-R-I-P-T-H-Y-I-V-K-D-G-K-Q-V-F-I-G-Y-E-Y-F-P-K-H-I-L-V-E-K-I-K-E-L-F-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-L-T-M-F-K-V-E-I-V-Q-L-P-K-K-V-L-R-Q-K-S-K-N-V-N-I-P-L-N-K-T-N-I-E-L-A-E-K-M-I-Y-H-I-D-D-S-Q-G-P-N-T-K-F-R-P-G-V-G-V-A-A-V-Q-Y-G-I-L-K-N-V-F-Y-V-C-V-P-N-D-S-R-L-T-Q-R-D-S-S-Q-E-V-K-P-E-D-K-Y-L-F-R-D-V-I-F-N-P-E-V-I-W-K-S-D-E-M-V-A-I-S-Q-G-E-G-C-L-S-V-D-E-S-W-P-N-Q-E-G-L-V-R-R-H-M-E-I-K-V-K-G-Y-S-Y-F-Q-K-K-E-M-I-W-H-V-K-G-Y-V-A-I-V-F-Q-H-E-L-D-H-L-N-G-M-L-F-I-D-R-I-D-P-K-R-L-W-D-K-S-G-I-K-V-L"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-I-N-I-H-K-R-N-I-V-L-L-V-G-P-S-G-V-G-K-G-T-I-E-K-I-L-F-E-S-K-T-L-K-L-S-L-S-R-S-A-T-T-R-K-K-R-E-G-E-I-N-G-I-H-Y-F-F-I-S-K-E-E-F-E-S-K-I-E-N-D-E-F-M-E-W-N-E-H-F-D-N-Y-Y-G-T-L-L-S-E-I-L-L-I-F-S-Q-G-R-I-P-V-L-E-V-E-T-Y-G-A-K-K-I-L-Q-K-Y-K-D-K-K-D-F-N-W-I-T-I-F-V-D-P-P-S-F-E-E-L-E-N-R-I-I-K-R-G-T-D-T-K-E-K-I-A-I-R-M-A-K-A-K-E-E-L-K-D-R-D-L-F-E-F-K-I-T-N-H-T-P-E-Q-A-A-E-E-I-E-K-I-I-L-K-K-T-M-G"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-Q-N-I-K-L-E-K-R-E-Q-D-I-L-I-N-I-S-R-I-I-S-E-E-V-Q-N-L-K-D-V-L-T-T-V-V-G-I-K-L-S-S-D-L-S-H-C-N-V-Y-V-T-F-S-K-N-S-K-K-N-L-E-R-L-N-Q-A-S-G-Y-I-K-K-Q-L-S-S-I-L-K-W-R-K-I-P-S-L-H-F-K-I-D-D-T-F-E-K-S-L-K-I-E-Q-I-L-E-E-I-K-K-E-K"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-L-L-Y-R-L-G-K-I-I-H-V-N-K-K-Y-I-I-F-E-S-D-S-A-G-Y-T-I-N-I-T-R-A-E-N-F-E-K-D-R-T-L-K-L-Y-I-Y-E-L-S-N-E-Y-Q-K-T-L-Y-G-F-T-H-F-K-E-R-V-L-F-E-D-L-I-S-I-N-G-I-G-P-R-I-A-L-I-L-L-N-D-G-W-E-K-I-A-S-L-I-A-N-G-N-W-E-T-L-S-R-Y-P-Y-I-N-V-K-N-C-H-Q-I-I-F-E-L-Q-N-K-W-A-K-F-L-E-K-D-E-K-V-P-S-A-N-I-Q-N-I-S-D-A-T-E-T-L-K-M-L-G-F-K-R-E-Q-I-K-Y-A-L-E-S-A-N-L-Q-D-D-V-E-T-L-V-E-N-A-I-K-K-I-S-T-V-N-G-K-E-A-R-N"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-K-I-K-S-I-K-T-M-E-K-A-R-K-R-N-S-M-I-K-S-R-V-K-T-S-I-K-K-A-K-L-A-I-T-Q-D-S-D-N-A-K-K-L-V-S-D-A-H-H-E-I-H-K-A-K-S-K-G-V-F-H-K-N-T-A-L-R-K-S-S-R-L-D-L-F-F-N-K-H-M-K-S-A"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-N-K-Y-E-I-V-I-M-L-D-P-A-E-N-I-E-K-A-Q-S-L-L-K-S-T-F-K-S-G-V-E-K-F-E-K-L-E-F-T-K-L-A-Y-E-I-N-K-S-K-V-A-Q-Y-V-L-A-I-V-N-S-Q-G-K-E-E-I-N-E-F-V-R-K-A-N-I-T-K-T-F-W-R-H-M-I-I-N-L-T-S-E-K-G-I-N-K-P-A-K-P-K-K-T-F-K-K-T-F-V-A-R-K-F-S-R-D-D-E-S-K-T-H-S-T-E-E-P-R-R-A-N-T-K-S-T-Y-K-K-S-T-S-F-S-Q-D-N-K-N-K-K"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-N-H-N-K-D-K-L-K-K-K-N-K-R-K-R-V-S-F-L-D-E-Q-G-I-N-Y-I-D-Y-K-D-V-E-L-L-S-K-F-I-N-S-H-G-K-I-L-P-S-K-I-T-D-V-S-A-K-R-Q-R-M-L-T-R-A-I-K-R-A-R-N-M-A-L-L-P-F-T-Q-E-R-V-R-T-Q-K-P-L-I-V-T-S-N-S-P-K-E-K-E-A-K-P-S-A-Q"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-K-E-K-L-A-M-K-F-K-S-F-D-H-K-L-V-D-D-A-V-K-K-V-L-I-L-A-S-K-E-K-I-D-Y-S-G-P-I-P-L-P-T-K-R-E-I-F-T-I-L-R-S-V-H-V-N-K-K-S-R-E-Q-F-E-R-R-T-Y-K-R-F-I-V-F-N-N-P-G-P-K-F-V-E-I-L-K-R-T-E-M-P-A-G-V-E-V-E-F-K-V-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-A-D-E-H-L-L-K-K-V-E-K-A-I-E-S-K-S-R-K-P-I-K-T-W-S-R-R-S-T-I-F-P-D-F-V-N-L-T-F-Q-V-H-N-G-K-N-F-I-D-V-F-V-T-D-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-G-G-H-G-E-D-K-R-K-K-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-V-R-A-L-L-K-T-V-R-V-S-S-K-K-A-S-L-V-A-N-L-F-R-H-Q-S-T-A-N-A-I-S-I-L-K-N-T-N-K-K-S-A-P-I-F-L-K-I-L-N-S-A-I-S-N-A-V-N-N-H-G-L-D-A-S-K-L-Y-V-S-N-V-M-V-N-E-G-P-T-L-K-R-F-Q-P-H-S-Q-G-R-A-T-R-I-L-K-R-T-S-H-L-S-V-M-V-S-E-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-H-R-K-M-F-R-I-R-H-D-K-K-D-A-F-K-G-N-K-V-S-F-G-E-Y-G-L-Q-A-T-T-S-A-W-I-T-A-R-Q-I-E-S-A-R-I-A-A-T-R-R-M-G-R-E-G-Q-V-I-I-R-I-F-P-H-L-S-K-T-S-K-P-I-G-V-R-M-G-S-G-K-G-S-P-E-K-W-Y-S-V-V-K-R-Q-T-M-M-F-E-V-S-G-I-K-P-E-V-A-K-D-A-L-R-L-A-G-H-K-L-P-V-K-W-R-I-V-E-A-S-P-K-E-E-V-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-I-N-T-R-K-A-L-V-G-S-V-V-S-S-V-N-D-K-T-I-I-V-A-V-D-I-Y-K-K-H-P-I-Y-S-K-R-F-K-K-T-K-R-F-A-A-H-D-E-Q-N-K-A-K-I-G-D-I-V-K-I-I-E-T-R-P-I-S-K-T-K-K-F-R-L-D-K-I-I-E-L-A-K-E-G-N"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-L-Q-E-L-S-V-A-K-V-A-D-N-S-G-A-K-E-V-G-I-I-R-N-L-G-G-S-V-K-K-S-S-N-I-G-D-V-V-I-C-S-V-K-K-A-I-P-N-G-I-V-K-K-G-Q-V-V-K-A-V-I-V-R-T-K-Y-G-I-K-R-E-N-G-Q-H-V-S-F-D-D-N-A-V-V-I-I-K-E-D-K-S-P-R-G-T-R-V-F-G-P-V-A-R-E-L-R-E-K-G-Y-L-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-T-K-L-R-K-N-D-E-V-I-V-I-A-G-S-Y-K-G-T-K-G-T-I-L-K-V-L-P-K-Q-Q-R-V-Q-V-K-G-V-N-V-V-T-K-H-V-K-P-S-Q-S-N-S-E-G-S-I-Q-N-F-E-A-P-I-H-I-S-N-V-A-Y-V-H-K-S-G-P-K-D-K-S-G-I-A-S-K-I-S-Y-E-K-R-K-D-K-K-V-R-I-A-R-K-T-G-K-V-I"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-I-L-K-E-K-Y-L-K-E-V-K-S-N-L-Q-K-Q-F-N-Y-S-S-S-M-E-I-P-R-I-E-K-V-I-L-N-M-T-A-G-K-E-V-T-N-A-K-A-I-E-E-V-I-N-E-L-T-L-I-S-G-Q-K-P-Y-Q-T-V-A-K-K-S-L-A-S-W-K-L-R-E-G-M-P-M-G-G-K-V-T-L-R-S-K-N-M-W-I-F-L-N-K-L-I-N-I-A-M-P-R-I-R-D-F-R-G-V-S-P-K-A-F-D-G-R-G-N-Y-S-L-G-I-K-E-Q-I-I-F-P-E-I-E-F-D-K-I-R-K-I-K-G-L-D-V-I-I-V-T-S-A-K-T-N-K-E-A-R-A-L-L-E-G-I-G-I-P-F-A-K-V-E-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-L-K-V-K-A-A-R-V-A-K-F-S-T-R-A-Y-T-R-C-Q-L-C-G-R-P-H-A-V-L-R-K-F-E-I-C-R-I-C-F-R-K-L-A-H-E-G-K-I-P-G-L-K-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-I-I-T-D-P-I-A-D-M-L-T-R-I-K-N-A-T-K-R-K-H-K-S-V-N-I-P-F-S-N-K-K-L-K-I-V-E-I-I-K-K-E-G-Y-I-S-G-Y-E-I-V-G-Q-G-I-E-K-K-I-L-I-T-L-K-Y-K-G-N-T-S-A-I-F-D-L-K-R-I-S-K-P-G-L-R-V-Y-T-T-A-S-N-I-P-S-V-L-S-G-Y-G-I-A-I-I-S-T-S-K-G-I-L-T-D-K-E-A-R-K-E-N-V-G-G-E-V-I-A-Y-I-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-R-I-I-Q-I-P-S-G-T-E-V-K-I-D-G-S-F-F-E-V-K-G-K-L-G-S-L-S-R-L-F-S-P-F-V-N-I-K-H-E-N-N-Q-I-S-V-E-R-L-N-E-L-K-P-T-K-Q-L-H-G-T-T-N-A-L-I-A-N-M-V-K-G-V-S-E-G-F-K-K-E-L-K-I-E-G-V-G-Y-K-A-T-L-K-G-Q-N-L-E-L-A-A-G-Y-S-H-P-V-S-L-V-I-P-K-D-L-K-V-E-V-P-K-P-V-N-I-I-I-S-G-I-D-K-Q-V-V-G-E-F-A-A-K-V-R-G-V-R-P-P-S-V-Y-S-G-K-G-I-Q-Y-K-D-E-K-L-R-R-K-E-G-K-K-A-S-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-K-L-S-R-N-Q-A-R-K-A-K-N-L-K-I-R-T-K-I-T-G-T-A-E-R-P-R-L-S-V-F-R-S-H-M-N-F-S-A-Q-L-I-D-D-S-K-S-I-T-I-V-G-I-T-T-A-K-K-G-S-K-E-Y-H-G-N-I-K-S-A-H-E-L-G-L-K-F-A-K-M-I-K-E-K-N-V-S-K-I-V-F-D-R-S-G-Y-L-Y-H-G-R-V-K-A-F-A-E-A-L-R-S-E-G-I-E-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-L-H-S-L-K-S-T-P-G-S-R-K-E-K-H-R-K-G-R-G-H-A-A-G-K-G-K-Q-A-G-K-G-Q-S-G-Q-R-K-R-S-K-V-R-L-G-F-E-G-G-Q-N-P-W-F-R-R-L-P-K-R-G-F-K-N-I-N-H-I-E-Y-Q-P-L-S-L-E-A-L-E-K-H-F-L-E-N-E-V-V-D-L-E-K-I-Y-E-K-R-L-V-T-K-R-T-L-P-V-K-L-L-A-N-G-K-L-T-K-K-L-T-I-H-V-H-S-A-S-Q-S-A-I-Q-A-V-E-S-L-G-G-K-V-E-V-L"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-D-K-S-I-K-M-Q-A-K-V-L-K-M-F-S-T-D-K-Y-E-L-E-L-L-E-N-K-V-I-I-K-G-H-I-S-G-K-M-R-I-H-K-I-R-I-L-P-G-D-I-V-D-V-E-I-S-P-H-D-L-S-N-G-R-I-T-Y-R-H-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-L-N-I-E-I-P-S-N-K-R-V-V-I-S-L-T-Y-I-L-G-I-G-K-S-L-S-K-E-I-I-V-K-A-N-E-K-L-A-K-A-K-E-K-T-F-T-E-D-S-R-V-K-D-L-S-E-E-Q-L-Q-A-I-R-D-S-A-K-T-Y-L-T-E-G-D-L-R-R-E-V-S-L-N-I-K-R-L-M-E-I-K-C-Y-R-G-I-R-H-R-K-G-L-P-V-R-G-Q-V-T-Q-K-N-A-R-T-R-K-G-P-R-K-T-V-A-G-K-K-G-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-Q-R-R-S-S-Q-T-T-K-K-V-K-R-K-N-V-T-N-G-V-A-H-I-H-S-T-H-N-N-T-I-V-T-F-S-D-E-K-G-N-V-I-S-W-A-S-S-G-T-I-G-Y-K-G-T-K-K-K-T-A-Y-A-A-G-L-A-A-Q-N-A-S-E-K-A-K-E-H-G-I-R-E-V-S-V-R-V-K-G-I-G-Q-G-R-D-A-A-R-K-Q-I-E-V-S-G-I-S-V-S-Q-I-V-D-V-T-P-Q-A-H-N-G-T-R-P-P-K-R-V-L-K-R-E-K-A-R"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-K-V-M-R-K-I-A-L-D-L-G-T-K-S-C-G-F-A-I-S-D-P-I-S-N-S-F-A-I-P-L-E-N-F-F-F-E-E-N-N-F-K-K-V-I-N-K-L-K-H-Y-E-K-K-Y-E-F-D-T-I-I-L-G-Y-P-L-R-M-T-G-T-R-S-E-R-S-I-M-V-E-E-F-E-K-L-L-R-K-T-F-S-Q-R-I-V-L-V-D-E-R-L-S-T-V-K-A-K-A-M-L-K-E-T-N-I-S-Q-S-K-I-K-E-K-K-D-S-M-A-A-A-L-L-L-N-Y-Y-L-N-N-F-L-G-V-R"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-E-E-K-N-K-I-Y-L-T-Q-E-T-I-K-K-Y-E-E-E-K-W-H-L-I-N-V-E-R-P-A-V-I-L-E-I-K-E-A-R-Q-Q-G-D-L-S-E-N-A-E-Y-D-A-A-R-E-K-Q-G-Q-I-E-D-R-I-T-E-L-E-N-I-L-S-N-A-I-S-I-Q-E-S-H-S-D-K-I-G-L-G-S-V-V-R-I-L-N-Q-S-T-G-K-E-R-T-F-K-I-V-G-S-F-D-T-D-P-T-Q-N-K-I-S-Y-E-S-P-L-A-K-S-I-I-G-F-S-K-G-D-V-V-E-I-D-A-P-D-K-Y-T-T-K-I-L-S-V-N-D-K"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-H-E-D-L-I-K-V-S-S-N-T-I-K-K-P-T-G-Q-V-F-V-V-Y-F-S-S-I-S-N-N-T-H-R-F-I-Q-K-L-N-Y-E-N-L-R-I-P-V-N-M-E-E-S-V-F-V-D-K-D-Y-V-I-F-V-P-T-Y-S-G-G-G-E-F-T-Q-G-A-V-P-K-Q-V-I-K-F-L-N-N-E-K-N-R-S-F-C-R-G-V-I-A-S-G-N-T-N-F-G-N-T-F-A-I-A-G-P-I-L-S-K-K-L-N-V-P-L-L-Y-Q-F-E-L-L-G-T-S-E-D-V-K-N-V-Q-N-I-L-E-T-F-W-K-T"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-I-L-I-K-D-C-P-S-G-K-A-N-T-I-V-E-V-S-D-G-Y-A-K-N-F-L-I-P-R-K-F-A-I-A-Y-T-E-E-N-A-K-K-L-K-Q-K-L-E-Q-E-K-L-D-F-S-L-K-T-K-E-F-L-E-L-K-E-K-L-E-K-L-K-L-T-F-K-L-K-A-S-L-D-K-N-H-K-L-E-T-H-H-S-I-S-A-K-K-L-L-E-R-L-H-E-L-G-F-D-L-P-K-H-S-I-E-K-V-H-L-N-L-I-G-I-N-H-V-N-V-K-L-F-D-K-I-V-A-K-L-T-V-V-I-E-A-D-V"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-N-V-N-E-F-K-P-G-I-T-F-E-D-E-G-N-I-Y-V-V-L-T-A-Q-H-S-K-Q-G-R-G-Q-A-N-V-K-A-K-V-K-N-L-R-T-G-S-T-T-L-K-S-Y-T-G-G-D-K-V-Q-K-A-H-I-E-K-K-P-M-D-Y-L-Y-N-D-G-S-N-I-I-L-M-D-Q-E-S-F-E-Q-I-E-I-D-V-K-K-V-E-W-E-L-N-F-L-T-E-G-M-K-I-L-V-R-Q-Y-Q-N-E-I-L-D-I-E-I-P-I-N-I-E-L-K-V-I-N-A-P-D-A-V-K-G-N-T-T-T-N-P-Q-K-K-V-I-V-E-T-G-Y-E-L-E-V-P-M-F-I-K-E-G-E-T-I-I-V-S-S-E-T-G-K-Y-G-G-K-S-S-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-Q-T-T-I-V-K-H-K-E-V-N-K-K-W-F-L-I-D-A-D-G-V-V-L-G-K-L-A-T-L-T-A-S-I-L-R-G-K-N-K-P-D-F-T-P-N-V-D-M-G-D-N-I-V-I-I-N-A-E-K-V-V-L-T-A-N-K-E-E-D-K-K-Y-Y-S-H-S-G-Y-P-G-G-L-K-V-I-N-A-A-K-L-R-A-K-K-P-I-A-I-V-E-K-A-V-K-G-M-L-P-H-T-K-L-G-R-Q-Q-F-R-N-L-Y-V-Y-A-G-S-V-H-K-Q-E-A-Q-Q-P-V-R-I-E-V-K"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-K-N-K-L-L-Q-L-V-E-Q-N-Q-I-R-K-D-L-P-N-F-N-T-G-D-N-V-K-V-H-L-R-I-K-E-E-N-K-E-R-I-Q-I-F-E-G-L-V-I-A-K-D-G-P-G-K-G-L-S-Q-S-F-K-V-R-K-I-S-S-G-I-G-V-E-K-D-F-P-L-N-S-P-I-I-S-A-I-E-V-I-R-R-N-K-V-R-R-K-K-L-Y-Y-I-R-N-K-S-G-K-S-A-R-L-K-E-K-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-T-K-G-R-K-R-K-A-S-K-T-K-S-P-A-L-N-Q-S-Y-N-S-L-H-K-K-Y-K-K-L-S-A-P-F-K-R-G-V-C-T-R-V-A-T-M-T-P-K-K-P-N-S-A-L-R-K-Y-A-R-V-K-L-S-N-G-M-E-V-T-A-Y-I-P-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-K-G-A-S-V-K-D-L-P-G-V-R-Y-S-I-I-R-G-T-Q-D-A-A-G-V-N-K-R-N-Q-A-R-S-R-Y-G-A-K-K-A-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-H-K-A-P-I-R-T-V-L-A-D-P-V-F-N-M-V-V-V-T-K-L-V-N-T-I-M-L-D-G-K-K-S-I-A-Q-N-I-V-Y-S-A-F-D-I-I-K-E-K-T-G-R-E-P-Y-E-V-F-Q-E-A-L-N-N-I-T-P-L-L-E-I-R-T-R-R-I-G-G-S-N-Y-Q-V-P-T-E-V-S-K-R-R-Q-Q-T-L-S-L-R-W-L-T-N-Y-A-R-L-R-N-E-K-T-M-D-L-R-L-A-N-E-I-I-D-A-S-N-K-T-G-G-A-I-K-K-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-F-R-W"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-N-I-I-N-I-T-N-K-S-N-F-R-F-M-Y-K-K-E-F-L-K-I-M-D-I-I-Q-E-K-F-N-F-K-K-R-I-S-V-D-L-L-I-T-D-N-K-E-V-R-E-N-N-L-L-Y-R-N-V-D-K-E-T-D-V-L-S-F-P-F-G-D-P-D-F-F-D-H-L-D-F-I-P-L-G-S-I-I-I-S-H-E-K-I-V-A-Q-A-L-E-F-N-H-S-K-K-R-E-F-C-Y-L-F-T-H-S-L-L-H-L-L-G-Y-D-H-K-E-E-D-E-E-K-I-M-N-Q-Y-T-K-E-I-V-E-K-L-N-I-Y-R"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-I-K-E-W-I-I-T-Q-L-S-K-L-T-K-N-K-I-T-E-E-S-L-F-S-E-I-G-I-D-S-L-D-L-V-E-H-V-S-D-L-E-Q-H-F-D-I-E-I-S-D-E-E-L-L-N-I-K-K-V-N-D-I-I-V-L-I-E-Q-K-S-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-L-I-T-K-N-K-Q-V-F-R-D-Y-E-I-I-D-K-L-E-A-G-I-V-L-Q-G-W-E-V-K-S-I-R-A-S-D-V-N-L-K-G-S-Y-C-V-F-K-A-N-E-L-Y-L-I-N-S-Y-I-G-L-Y-M-A-V-K-G-D-E-R-Q-S-R-K-L-L-L-H-K-N-Q-L-R-R-L-K-Q-K-V-E-S-Q-S-L-S-I-V-P-L-S-L-Y-W-N-K-K-S-K-V-K-A-E-I-A-L-V-R-G-L-K-K-H-D-K-R-E-K-L-K-K-E-E-T-N-K-K-L-K-K-L-I-S-Y"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-E-V-G-G-K-Q-L-L-V-K-E-Q-E-V-I-F-T-E-K-I-E-G-N-A-G-E-K-V-E-F-D-K-V-L-L-F-G-D-K-V-G-R-P-Y-L-E-K-V-K-V-I-G-E-I-Q-K-Q-S-K-H-K-K-I-I-V-Y-R-H-N-A-K-S-T-H-K-R-K-L-G-H-R-Q-P-Y-T-R-V-K-I-L-E-I-K-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-T-D-K-K-L-V-K-E-L-A-I-E-F-G-G-S-E-K-N-V-G-A-I-E-V-Q-I-A-I-L-T-H-D-I-E-R-L-K-I-H-F-E-T-N-K-K-D-K-H-S-K-R-G-F-I-A-K-I-N-K-R-K-K-L-L-A-Y-L-K-D-V-N-F-E-S-Y-Q-T-T-I-Q-K-L-K-I-R-K"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-N-L-E-K-F-I-K-D-V-K-D-F-P-K-Q-G-I-N-F-K-D-I-S-P-L-L-A-N-G-Q-A-L-N-Y-T-I-K-K-M-A-E-L-A-K-D-A-D-I-I-V-G-P-D-A-R-G-F-L-F-G-T-P-T-A-A-F-L-S-K-P-F-I-M-V-R-K-K-G-K-L-P-G-E-V-I-K-H-E-Y-D-L-E-Y-G-K-D-I-L-E-I-Q-K-G-V-I-K-P-G-D-K-A-I-I-I-D-D-V-L-A-T-G-G-T-T-K-A-I-I-D-L-L-E-S-Q-G-A-K-V-I-K-I-I-L-L-L-E-L-T-N-L-N-G-R-S-K-F-G-S-L-Q-V-E-S-L-V-K-V-S-V"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-H-I-E-S-K-N-R-Q-I-K-K-D-I-V-V-E-I-T-K-K-I-N-D-S-Q-S-L-F-L-A-E-Y-R-G-L-T-V-A-K-L-L-N-L-R-K-E-A-K-K-H-N-V-E-I-K-V-Y-K-N-R-L-V-K-L-A-T-Q-K-L-G-H-S-D-L-D-K-F-L-V-G-P-N-L-F-V-F-S-N-E-L-G-M-D-G-A-K-V-L-A-E-F-A-K-K-N-K-K-L-V-L-K-A-G-I-F-D-G-K-V-V-D-A-A-G-V-K-A-V-A-E-L-P-T-Y-E-E-A-L-T-I-L-A-S-S-L-L-G-P-L-R-Q-I-S-L-S-F-K-L-L-V-D-E-N-K-L-S-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-L-T-K-E-T-F-I-A-S-L-K-E-M-N-I-Q-E-V-M-E-L-V-Q-A-M-K-D-E-F-G-I-D-P-S-A-V-A-V-A-A-G-P-A-A-E-V-S-E-E-K-T-S-F-N-V-I-L-K-S-D-G-G-A-K-I-A-V-I-K-A-I-K-E-A-L-G-L-S-I-M-D-A-K-K-M-V-E-S-T-P-V-A-I-K-E-N-L-K-A-D-E-A-E-E-L-R-K-S-I-A-A-S-G-A-E-V-V-V-E"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-F-G-A-N-L-L-T-N-Y-N-E-E-L-T-E-K-F-Y-R-L-F-P-S-I-P-L-M-L-A-T-L-A-A-L-V-I-S-I-F-F-L-T-Y-F-F-Y-K-P-I-R-K-N-I-K-K-R-K-Q-Y-I-Q-D-N-I-D-A-A-N-K-L-K-Q-Q-S-L-E-N-L-E-E-S-N-K-K-L-N-E-A-R-E-Q-A-S-E-I-I-N-S-S-K-R-D-A-E-L-I-V-I-N-Y-K-M-S-A-Q-K-K-S-E-E-I-L-K-K-A-Q-L-E-I-K-R-K-E-E-E-F-L-R-T-S-R-E-E-I-I-D-A-A-T-I-I-A-K-K-I-L-I-K-E-I-D-S-N-Y-E-K-K-I-I-D-D-I-S-F-D-S-E-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-I-D-N-H-Y-V-Q-S-S-A-K-A-L-S-Q-I-A-F-E-E-K-K-E-K-L-F-L-N-Q-L-F-I-I-K-N-I-F-S-Y-N-P-E-V-V-E-Y-L-A-S-G-S-I-K-L-E-N-K-K-K-F-I-E-E-I-F-D-L-I-E-P-L-I-L-N-F-L-L-M-A-V-E-D-N-K-I-K-Y-L-D-N-I-F-L-K-A-I-L-T-I-N-K-K-L-N-I-E-N-G-I-I-Y-T-T-L-K-L-S-D-K-K-L-L-E-I-E-K-K-L-S-V-F-L-K-K-E-V-K-L-L-N-L-I-D-K-E-L-I-S-G-Y-E-I-Q-V-G-D-F-K-Q-R-N-N-V-A-S-W-I-D-Q-M-A-L-S-I-K-K-G-D"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-Q-L-Q-L-I-I-T-T-P-N-G-I-F-F-N-E-K-V-D-I-V-T-V-V-T-A-G-G-H-I-G-I-Q-Y-G-H-Q-P-L-I-S-T-I-E-I-S-E-L-H-I-N-T-E-G-H-K-D-Y-R-I-C-S-I-N-G-G-L-L-Y-V-E-K-D-K-A-N-I-I-T-G-A-I-E-F-K-E-D-I-D-I-E-K-A-R-R-E-H-D-Y-L-V-E-I-L-S-N-S-K-N-K-D-S-D-Y-F-R-N-E-L-K-L-K-K-V-I-N-R-L-K-I-S-S-N-S-T-Q-S-P-K-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-R-V-K-G-G-T-V-T-R-A-R-R-K-K-W-L-K-L-A-K-G-Y-W-G-H-K-S-I-G-Y-K-V-A-K-Q-A-V-V-K-S-W-T-Y-A-F-R-D-R-K-Q-V-K-R-N-F-R-K-L-W-I-S-R-I-N-A-A-V-R-P-L-G-M-S-Y-S-Q-F-I-N-G-L-K-K-A-N-V-K-I-N-R-K-M-L-S-E-L-A-I-R-E-M-K-T-F-E-M-L-V-S-I-S-K-S-S-K"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-N-T-E-Q-H-Q-K-K-G-Q-K-N-K-V-L-L-N-N-D-I-P-F-S-K-V-F-L-I-G-E-D-G-E-K-I-G-I-K-T-K-E-E-A-L-D-I-A-R-G-E-K-K-D-L-V-L-I-S-V-Q-P-K-P-I-A-R-I-L-D-Y-G-K-F-K-Y-D-R-K-K-K-E-K-E-Q-K-E-K-Q-T-N-I-N-N-R-Q-I-R-L-T-P-L-I-G-D-H-D-L-L-T-K-A-K-K-T-R-E-L-L-L-K-G-D-R-I-K-V-S-L-K-F-K-G-R-E-I-A-R-K-E-L-G-I-D-T-L-N-R-F-Y-E-Q-V-E-D-I-A-K-I-D-K-E-P-K-L-N-Q-D-R-F-L-D-M-Y-L-H-P-D-K-Q-K-I-A-K-Y-L-K-E-K-G-E-D-N-A-K-N-E-K"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-N-I-I-S-V-G-T-L-S-K-E-F-Q-V-I-F-D-D-Y-I-K-K-I-N-F-Y-S-N-V-N-L-I-K-I-K-E-F-K-S-N-N-K-D-L-I-I-K-N-E-T-M-A-I-L-E-K-I-P-K-N-S-K-V-F-L-C-S-L-N-A-E-Q-Y-S-S-E-K-F-A-L-F-L-Q-E-D-N-I-S-F-V-I-G-G-S-H-G-V-D-E-K-M-F-K-G-A-W-K-I-N-F-S-K-M-T-F-P-H-Q-L-F-H-L-M-L-I-E-Q-I-Y-R-G-F-S-I-L-N-N-K-I-Y-H-K"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-L-H-F-I-K-S-A-S-N-S-Q-S-W-Y-N-H-D-K-V-E-I-C-F-I-G-R-S-N-V-G-K-S-S-L-I-N-S-L-S-N-S-A-V-S-K-V-S-N-T-P-G-R-T-Q-L-I-N-F-F-E-D-D-Q-K-N-V-Y-V-D-L-P-G-Y-G-F-A-Q-M-P-K-D-K-L-E-K-M-H-Q-M-I-D-E-Y-L-Q-N-R-K-N-L-K-T-I-V-L-L-F-D-S-R-R-G-I-L-D-Q-D-L-D-F-I-N-W-A-Q-Q-A-K-K-N-I-I-L-L-A-T-K-I-D-K-L-N-Q-A-Q-K-H-K-L-L-V-S-L-K-E-L-N-L-E-K-S-V-L-L-V-S-S-L-K-R-T-N-I-D-N-L-K-K-L-L-A-S-E-F-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-D-I-S-I-I-N-E-V-F-S-T-L-E-E-K-S-M-N-V-V-S-N-F-E-F-N-L-S-K-I-S-T-G-R-A-N-P-Q-L-I-K-N-I-K-V-S-Y-Y-E-E-L-I-P-L-E-Q-I-S-N-I-S-V-P-E-P-Q-Q-L-L-I-K-P-F-D-H-N-I-T-K-E-I-H-K-S-L-L-L-A-N-L-D-V-A-I-V-N-E-G-N-Q-I-R-L-N-F-P-A-L-N-T-Q-R-R-K-E-L-V-K-S-L-N-K-F-T-E-Q-A-R-V-S-I-R-L-L-R-Q-E-S-N-K-K-I-K-S-F-K-S-E-I-S-E-D-D-I-K-K-Y-E-T-K-I-Q-T-I-N-D-S-Y-I-E-Q-I-D-E-I-T-K-R-K-E-R-E-L-M-E-I"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-I-Y-H-I-R-K-N-W-E-F-Q-A-I-I-N-S-K-R-Q-V-I-S-K-N-L-I-F-Y-Y-Q-R-N-N-T-F-K-I-G-V-S-I-P-K-K-F-A-G-A-V-K-R-N-F-Y-K-R-Q-I-M-A-I-L-R-D-I-Q-D-L-T-N-L-E-Y-K-I-V-M-I-V-R-K-N-F-M-A-L-D-F-L-E-K-K-K-E-I-Q-K-M-L-E-R-F-K-N-E-K-R-K"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-K-N-K-I-L-V-K-N-N-E-L-T-V-D-I-S-A-F-D-D-K-D-E-V-L-S-L-Q-R-K-N-F-N-L-I-L-G-K-D-S-F-L-R-G-F-D-A-N-L-I-G-Q-K-S-L-P-L-Y-E-F-S-M-V-I-P-S-D-F-K-D-E-K-L-R-G-K-T-L-D-F-K-V-H-N-K-A-K-I-K-V-N-S-E-T-N-L-D-K-E-K-I-K-S-L-E-K-E-L-A-N-Q-K-E-K-N-A-L-L-L-L-D-N-V-K-L-K-S-E-K-E-K-I-I-K-D-F-K-D-E-I-K-T-F-E-N-R-A-R-E-K-I-A-E-K-L-N-L-E-K-Q-L-L-E-N-K-F-E-D-F-K-K-Y-G-S-Q-K-I-F-E-S-I-M-P-I-I-Q-N-L-L-V-A-I-E"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-Q-K-D-I-H-L-K-M-E-P-L-K-I-T-C-S-T-C-F-T-S-F-D-I-V-S-S-R-K-T-I-A-I-D-I-C-S-K-C-H-P-F-Y-T-G-D-R-T-L-A-K-A-T-G-Q-I-D-K-F-Q-K-R-L-Q-K-K-Q-K"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-T-L-I-M-I-G-V-D-L-V-K-I-E-R-L-E-N-K-S-D-H-F-V-R-K-I-L-S-L-D-E-Y-E-L-Y-Q-K-T-K-A-K-A-I-F-L-A-T-R-W-A-I-K-E-A-L-F-K-A-D-N-Q-H-F-C-F-K-K-I-N-I-T-K-K-D-N-V-Y-K-F-D-G-F-A-I-S-V-S-S-E-K-E-Y-V-I-A-F-V-Q-K-I-G-V-A-C-H-R-D"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-K-N-Q-Y-I-D-N-L-I-L-N-L-K-K-L-P-G-V-G-T-K-Q-A-E-K-I-S-F-F-L-L-K-Q-N-E-N-E-V-E-Q-I-I-N-S-I-V-D-L-K-K-N-I-K-E-C-Q-N-C-N-F-L-Q-S-N-N-I-C-H-F-C-M-D-K-S-R-N-K-Q-L-M-I-F-E-T-T-S-D-A-L-K-F-E-K-L-G-I-Y-R-G-K-Y-F-I-I-K-N-L-I-E-N-V-K-N-A-N-E-P-K-W-K-D-K-L-L-H-Y-A-S-N-F-E-E-I-I-I-A-L-N-P-T-I-E-G-Q-I-T-S-N-Y-I-K-V-I-L-E-E-V-A-L-K-V-T-K-L-A-Q-G-L-P-I-N-S-Q-I-D-Y-I-D-P-I-T-L-N-L-S-F-E-N-R-K"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-N-N-M-N-I-N-E-M-L-K-Q-A-K-K-M-Q-S-E-I-E-L-K-E-K-E-L-Y-K-K-E-F-T-I-E-K-Q-G-L-T-L-V-L-N-G-K-R-E-V-L-K-I-D-I-N-E-A-L-V-D-P-E-D-K-D-I-L-E-D-L-L-L-L-A-F-N-E-A-M-E-K-I-D-E-A-H-K-E-I-E-K-Q-I-P-S-G-K-L-P-F"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-E-V-V-K-I-A-K-L-Q-F-I-A-G-Q-A-K-P-G-P-S-L-A-G-V-G-I-N-M-P-E-F-T-R-Q-F-N-E-Q-T-R-D-R-G-N-E-P-V-P-V-E-I-T-A-Y-K-D-K-S-F-D-F-R-L-F-T-A-P-A-S-F-K-I-L-Q-A-I-K-A-K-S-G-S-A-N-S-K-T-N-I-I-G-T-L-T-L-A-Q-L-E-E-I-A-K-Y-K-L-P-D-L-N-T-D-D-Y-K-V-A-M-H-T-I-A-G-T-A-K-N-M-G-V-L-V-E-G-W-D-D-V-K-K-A-K-E-E-A-K-A-A-K-L-A-Q-L-K-A-E-A-K-E-A-A-L-K-E-A-E-K-E-L-V-D-S-K-G-K-E-V-E-V-K-L-V-G-E-E-E-Q-S-E-S-E-N-N"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-I-I-Y-K-D-I-I-T-G-D-E-M-F-S-D-I-Y-K-I-K-E-S-E-N-G-M-M-I-E-V-E-G-K-M-I-S-R-A-E-G-E-I-D-D-A-L-I-G-G-N-A-S-A-E-V-Q-D-E-G-C-E-S-T-T-V-S-G-V-D-I-V-L-N-H-K-L-Q-E-T-S-Y-D-K-K-S-Y-T-A-Y-I-K-D-Y-M-K-A-V-K-A-K-L-Q-E-V-A-P-D-R-V-D-P-F-M-A-N-A-P-A-E-V-K-K-I-L-G-N-I-K-N-F-Q-F-F-T-G-E-S-M-N-P-D-G-M-I-G-L-L-D-F-R-E-D-G-V-T-P-Y-M-L-F-F-K-D-G-L-E-I-E-K-C"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-I-R-Y-P-M-A-V-G-L-N-K-G-Y-K-V-T-K-N-V-S-K-P-R-H-C-R-R-R-G-R-L-T-K-H-T-K-F-V-R-D-M-I-R-E-V-C-G-F-A-P-Y-E-R-R-A-M-E-L-L-K-V-S-K-D-K-R-A-L-K-F-I-K-K-R-V-G-T-H-I-R-A-K-R-K-R-E-E-L-S-N-V-L-A-A-M-R-K-A-A-A-K-K-D"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-K-I-K-A-R-D-L-R-G-K-K-K-E-E-L-L-K-Q-L-D-D-L-K-V-E-L-S-Q-L-R-V-A-K-V-T-G-G-A-A-S-K-L-S-K-I-R-V-V-R-K-S-I-A-R-V-L-T-V-I-N-Q-T-Q-K-E-N-L-R-K-F-Y-K-G-K-K-Y-K-P-L-D-L-R-P-K-K-T-R-A-M-R-R-R-L-N-K-H-E-E-N-L-K-T-K-K-Q-Q-R-K-E-R-L-Y-P-V-R-K-Y-A-I-K-A"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-P-V-K-K-P-A-A-K-G-G-K-K-K-K-Q-V-L-K-F-T-L-D-C-T-H-P-V-E-D-G-I-M-D-A-A-N-F-E-Q-F-L-Q-E-R-I-K-V-N-G-K-A-G-N-L-G-G-G-V-V-T-I-E-R-S-K-S-K-I-T-V-T-S-E-V-P-F-S-K-R-Y-L-K-Y-L-T-K-K-Y-L-K-K-N-N-L-R-D-W-L-R-V-V-A-N-S-K-E-S-Y-E-L-R-Y-F-Q-I-N-Q-D-E-E-E-E-E-E-E-D"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-P-A-K-G-P-L-Q-S-V-Q-V-F-G-R-K-K-T-A-T-A-V-A-H-C-K-R-G-N-G-L-I-K-V-N-G-R-P-L-E-T-I-E-P-A-T-L-Q-Y-K-L-L-E-P-V-L-L-L-G-K-E-R-F-A-G-V-D-I-R-V-R-V-K-G-G-G-H-V-A-Q-V-Y-A-I-R-Q-A-I-S-K-A-L-V-A-Y-Y-Q-K-Y-V-D-E-A-S-K-K-E-I-K-D-I-L-I-Q-Y-D-R-T-L-L-V-A-D-P-R-R-C-E-S-K-K-F-G-G-P-G-A-R-A-R-Y-Q-K-S-Y-R"} +{"text": "### FUNCTION Stimulates the phosphotransfer from phospho-DegS to DegU Affects protease and levansucrose production ### SEQUENCE -M-E-K-K-L-E-E-V-K-Q-L-L-F-R-L-E-L-D-I-K-E-T-T-D-S-L-R-N-I-N-K-S-I-D-Q-L-D-K-Y-N-Y-A-M-K-I-S"} +{"text": "### FUNCTION Possibly has a role in RNA transcription or processing during stress ### SEQUENCE -N-S-L-H-S-A-F-S-T-Y-G-E-V-L-E-S-K-I-I-L-D-R-E-T-Q-R-S-R-G-F-G-F-V-T-F-S-T-E-E-A-M-R-S-A-I-E-G-M-N-G-K-E-L-D-G-R-N-I-T-V-N-E-A-Q-S-R-G-G-R-G-G-G-G-G-G-G-Y-G-G-G-R-G-G-G-G-G-Y-G-R-R-D-G-G-G-G-G-Y-G-G-G-G-G-G-Y-G-G-G-R-G-G-Y-G-G-G-G-Y-G-G-G-G-G-G-Y-G-G-G-S-R-G-G-G-G-Y-G-N-S-D-G-N-W-R-N"} +{"text": "### FUNCTION Possibly has a role in RNA transcription or processing during stress ### SEQUENCE -M-A-A-A-D-V-E-Y-R-C-F-V-G-G-L-A-W-A-T-N-N-E-T-L-E-Q-A-F-A-N-F-G-Q-V-I-D-S-K-V-I-T-D-R-E-T-G-R-S-R-G-F-G-F-V-T-F-S-S-E-Q-S-M-L-D-A-I-E-N-M-N-G-K-E-L-D-G-R-N-I-T-V-N-Q-A-Q-S-R-G-G-G-G-G-G-G-G-Y-G-G-G-G-G-G-Y-G-G-R-E-G-G-G-Y-G-G-G-G-G-G-Y-G-G-R-R-E-G-G-G-G-Y-G-G-G-G-Y-G-G-G-G-G-G-Y-G-G-R-E-G-G-G-G-Y-G-G-G-G-G-Y-G-G-N-R-G-D-S-G-G-N-W-R-N"} +{"text": "### FUNCTION Could be a structural protein required for the infection process of Blactucae ### SEQUENCE -M-K-F-S-Q-I-L-V-L-A-A-I-A-V-A-A-I-S-A-Q-D-A-A-P-A-T-T-P-D-T-A-T-A-T-T-P-A-A-A-T-T-T-T-T-T-T-T-P-A-A-D-A-G-T-A-S-T-E-Q-T-T-T-A-G-P-E-A-A-G-A-T-N-G-T-T-T-T-P-P-A-D-G-T-Q-T-A-T-A-P-L-D-A-T-A-T-E-E-S-S-A-S-G-E-M-T-P-T-V-G-T-D-T-S-D-Q-V-S-D-S-T-A-A-G-P-S-T-P-E-G-S-M-T-G-T-S-T-P-K-A-S-D-S-S-S-S-A-T-D-T-T-S-G-A-S-H-T-T-M-A-V-A-C-A-T-V-M-T-V-G-A-Y-F-L"} +{"text": "### FUNCTION Involved in cell lysis upon induction of PbsX ### SEQUENCE -M-N-T-F-D-K-G-T-V-I-R-T-V-L-L-L-I-A-L-I-N-Q-T-M-L-M-L-G-K-S-P-L-D-I-Q-E-E-Q-V-N-Q-L-A-D-A-L-Y-S-A-G-S-I-A-F-T-I-G-T-T-L-A-A-W-F-K-N-N-Y-V-T-E-K-G-K-K-Q-R-D-L-L-R-D-N-N-L-T-K"} +{"text": "### FUNCTION Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures ### SEQUENCE -H-V-V-A-A-I-T-A-L-K-E-R-G-G-S-S-M-K-K-Q-S-V-F-I-K-K-A-L-K-S-G-V-E-K-G-T-L-V-Q-V-K-G-K-G-A-S-G-S-F-K-L-G-K-K-P-A-A-G-R-T-D-A"} +{"text": "### FUNCTION Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures ### SEQUENCE -H-V-V-A-A-I-T-A-L-K-E-R-G-G-S-S-H-Q-A-L-K-K-Y-K-A-A-N"} +{"text": "### FUNCTION Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures ### SEQUENCE -P-G-S-P-Q-K-R-A-A-S-P-R-K-S-P-R-K-G-S-P-K-K-S-P-M-I-R-A-A-I-T-A-M-R-E-R-K-G-S-S-V-A-K-I-K-S-Y-I-A-A-N-Y-R-V-N-M-T-N-L-Q-P-H-I-R-R-A-L-R-S-G-V-A-S-G-A-L-K-Q-V-T-G-T-G-A-T-G-R-F-R-V-G"} +{"text": "### FUNCTION Binds double-strand RNA with high affinity Suppresses the host RNA silencing-based antiviral response ### SEQUENCE -M-Q-S-K-L-A-L-I-Q-E-L-P-D-R-I-Q-K-A-V-E-V-V-L-A-M-S-Y-Q-E-A-P-N-N-V-R-R-D-L-D-N-L-Q-A-C-L-N-K-A-K-Q-T-V-N-R-M-V-T-S-L-L-D-K-P-S-M-A-A-Y-L-E-G-K-P-L-P-E-E-R-P-T-L-E-E-R-L-R-K-L-E-L-S-R-E-P-P-P-T-R-S-D-P-A-P-A-K-L"} +{"text": "### FUNCTION May counteract the cellular interferon antiviral system ### SEQUENCE -M-M-A-S-I-L-L-T-L-F-R-R-T-K-K-K-Y-R-R-H-T-D-D-Q-V-F-N-N-P-A-S-K-I-K-Q-K-P-G-K-I-F-C-S-A-P-V-E-N-L-N-K-L-R-G-E-C-L-R-M-M-E-M-L-K-E-E-T-W-R-I-Y-P-V-L-L-P-Q-M-E-L-L-E-R-E-C-R-T-P-V-T-G-Q-K-V-Q-M-T-Y-N-W-T-Q-W-L-Q-T-L-Y-T-M-I-M-E-E-N-V-P-D-M-D-L-L-Q-A-L-R-E-G-G-V-I-T-H-Q-E-Q-T-M-G-M-Y-V-L-Y-L-M-Q-R-C-C-P-M-L-P-K-L-Q-F-L-K-K-I-G-K-L-I"} +{"text": "### FUNCTION May be a component of ribonuclease P or MRP ### SEQUENCE -M-E-Q-Y-R-R-A-G-S-V-E-L-P-A-S-S-P-M-P-Q-L-P-P-D-T-L-E-M-R-V-R-D-G-S-K-I-R-N-L-L-G-L-A-L-G-R-L-E-G-G-S-T-R-H-V-V-F-S-G-S-G-R-A-A-G-K-A-V-S-C-A-E-I-V-K-R-R-V-P-G-L-H-Q-L-T-K-L-R-F-L-Q-T-E-D-S-W-V-P-T-S-P-D-T-G-L-D-P-L-T-V-R-R-H-V-P-A-V-W-V-L-L-S-R-D-P-L-D-P-S-E-C-G-Y-Q-P-P-G-A-P-P-G-L-G-S-I-P-S-P-S-C-G-P-R-P-R-R-R-A-R-D-T-R-S"} +{"text": "### FUNCTION Involved in the biogenesis of the 60S ribosomal subunit Ensures the docking of GTPBP4/NOG1 to pre-60S particles ### SEQUENCE -M-R-I-E-K-C-Y-F-C-S-G-P-I-Y-P-G-H-G-M-M-F-V-R-N-D-C-K-V-F-R-F-C-K-S-K-C-H-K-N-F-K-K-K-R-N-P-R-K-V-R-W-T-K-A-F-R-K-A-A-G-K-E-L-T-V-D-N-S-F-E-F-E-K-R-R-N-E-P-V-K-Y-Q-R-E-L-W-N-K-T-I-D-A-M-K-R-V-E-E-I-K-Q-K-R-Q-A-K-F-I-M-N-R-L-K-K-N-K-E-L-Q-K-V-Q-D-I-K-E-V-K-Q-N-I-H-L-I-R-A-P-L-A-G-K-G-K-Q-L-E-E-K-M-V-Q-Q-L-Q-E-D-V-D-M-E-E-A-S"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity Specifically involved in maintaining stability of STT3A-containing OST complexes ### SEQUENCE -M-I-T-D-V-Q-L-A-I-F-A-N-M-L-G-V-S-L-F-L-L-V-V-L-Y-H-Y-V-A-V-N-N-P-K-K-Q-E"} +{"text": "### FUNCTION Involved in an early step of the mitochondrial complex IV assembly process ### SEQUENCE -M-P-R-Y-Y-E-D-K-P-E-G-G-A-C-A-G-V-K-E-D-L-G-A-C-L-L-Q-S-A-C-V-L-Q-E-G-K-S-P-R-Q-C-L-K-E-G-N-C-R-A-L-Q-Y-S-F-F-E-C-K-R-S-M-L-D-A-R-S-R-F-R-G-R-K-G-Y"} +{"text": "### FUNCTION Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle ### SEQUENCE -M-L-S-R-K-A-V-A-A-L-L-L-V-H-V-T-A-M-L-A-S-Q-T-E-G-F-V-P-I-F-T-Y-S-E-L-R-R-T-Q-E-R-E-Q-N-K-R-L-R-K-S-L-R-V-Q-Q-R-S-K-A-A-G-R-L-E-P-Q-E-V-M-E-E-E-E-N-G-V-I-K-L-T-A-P-V-E-I-G-V-G-L-S-S-R-Q-L-E-K-H-R-A-V-L-E-A-L-L-S-E-A-L-P-P-P-S-L-V-F-G-G-Q-R-P-V-T-A-A-W-E"} +{"text": "### FUNCTION Participates in tumor necrosis factor-alpha -induced cell death May be a target of Wnt/beta-catenin signaling in the liver ### SEQUENCE -M-D-H-K-P-L-L-Q-E-R-P-P-A-Y-N-L-E-A-G-Q-G-D-Y-A-C-G-A-P-G-Y-G-A-I-P-S-A-P-P-P-P-P-Y-P-Y-L-V-T-G-I-P-T-P-H-P-R-V-Y-S-I-H-S-R-T-V-T-R-Y-P-A-N-S-I-V-V-V-G-G-C-P-V-C-R-V-G-V-L-E-D-C-F-T-F-L-G-I-F-L-A-I-I-L-F-P-F-G-F-I-C-C-F-A-L-R-K-R-R-C-P-N-C-G-A-T-F-T"} +{"text": "### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-Y-Y-Y-G-N-Y-Y-G-G-L-G-Y-G-L-G-G-F-G-G-F-G-G-L-G-Y-G-Y-G-S-S-Y-G-L-G-G-Y-G-G-Y-G-Y-F-S-P-S-F-Y-G-G-Y-L-S-S-G-F-Y"} +{"text": "### FUNCTION Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system Not activated by UDP ### SEQUENCE -L-P-L-S-Y-G-V-V-C-V-L-G-L-C-L-N-V-V-A-L-Y-I-F-L-C-R-L-K-T-W-N-A-S-T-T-Y-M-F-H-L-A-V-S-D-S-L-Y-A-A-S-L-P-L-L-V-Y-Y-Y-A-Q-G-D-H-W-P-F-S-T-V-L-C-K-L-V-R-F-L-F-Y-T-N-L"} +{"text": "### FUNCTION Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system Not activated by UDP ### SEQUENCE -V-H-F-S-S-S-V-M-V-L-L-F-G-L-P-F-L-V-T-L-V-C-Y-G-L-M-A-L-R-L-C-R-P-L-P-G-A-G-Q-S-S-S-R-L-R-S-L-R-T-I-A-V-V-M-T-V-F-A-V-C-L-V-P-F-H-I-T-R-T-I-Y-Y-L-A-R-L-L-K-A-D-C-Q-I-L-N-I-V-N-V-V-Y-K-V-T-R-P-L-A-S-A-N-S-C-L-D-P-L-L-Y-L-F-T-G-D-K-Y-R-H-Q-L-Q-R-L-C-R-V-S-A-P-Q-R-R-I-T-A"} +{"text": "### FUNCTION Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, ie the esterification of glucose at the C6'' position with the carboxyl group of the C ### SEQUENCE -M-K-T-M-K-K-Y-I-K-T-A-F-F-C-S-M-Y-W-L-I-V-Q-L-N-I-A-N-L-G-T-R-I-P-D-K-Y-F-R-Q-K-Y-I-I-F-K-S-F-N-F-E-K-H-G-K-F-W-N-K-W-F-Y-V-R-K-W-K-H-K-I-L-D-G-H-Q-L-N-Q-N-I-Y-D-Q-R-H-L-M-T-I-N-T-D-E-I-E-K-M-I-I-E-T-K-R-A-E-L-I-H-W-I-S-I-L-P-V-I-I-F-N-K-G-S-R-L-V-K-Y-I-N-I-F-Y-A-M-I-A-N-V-P-I-I-I-V-Q-R-Y-N-R-P-R-L-T-Q-L-L-R-I-L-K-R-R-G-E-R-H-D"} +{"text": "### FUNCTION Chaperone that serves for the intracellular sequestration and transport of Cu ### SEQUENCE -M-S-Q-E-I-L-N-V-E-G-M-S-C-G-H-C-K-S-A-V-E-S-A-L-N-N-I-D-G-V-T-S-A-D-V-N-L-E-N-G-Q-V-S-V-Q-Y-D-D-S-K-V-A-V-S-Q-M-K-D-A-I-E-D-Q-G-Y-D-V-V"} +{"text": "### FUNCTION Transcriptional regulator acting as an intermediary between major regulators SarA and agr and virulence genes Represses alpha-hemolysin ### SEQUENCE -M-N-D-L-K-S-K-S-N-I-K-L-M-K-R-V-L-T-T-Y-E-L-R-K-Y-L-K-K-Y-F-C-L-T-L-D-N-Y-L-V-L-A-Y-L-D-V-F-K-N-D-E-G-K-Y-F-M-R-D-I-I-S-Y-I-G-I-D-Q-S-R-I-V-K-S-V-K-E-L-S-K-K-G-Y-L-N-K-C-R-D-P-H-D-S-R-N-V-I-I-V-V-S-V-K-Q-H-N-Y-I-K-N-L-L-S-E-I-N-I-N-E-T"} +{"text": "### FUNCTION Activates transcription of virulence factors alpha- and beta hemolysin genes ### SEQUENCE -M-Y-V-E-N-S-Y-L-S-K-Q-L-C-F-L-F-Y-V-S-S-K-E-I-I-K-K-Y-T-N-Y-L-K-E-Y-D-L-T-Y-T-G-Y-I-V-L-M-A-I-E-N-D-E-K-L-N-I-K-K-L-G-E-R-V-F-L-D-S-G-T-L-T-P-L-L-K-K-L-E-K-K-D-Y-V-V-R-T-R-E-E-K-D-E-R-N-L-Q-I-S-L-T-E-Q-G-K-A-I-K-S-P-L-A-E-I-S-V-K-V-F-N-E-F-N-I-S-E-R-E-A-S-D-I-I-N-N-L-R-N-F-V-S-K-N-F-D-Y-S-D-R-K"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-V-E-E-I-Q-G-N-I-A-N-L-S-N-S-E-K-Q-K-H-V-E-K-V-Y-L-E-N-S-D-L-V-K-R-I-Q-R-V-V-T-D-H-G-T-E-I-G-I-R-L-K-Q-P-I-D-L-Q-Y-G-D-I-L-Y-A-D-D-H-N-M-I-I-V-D-V-N-S-E-D-L-L-V-I-Q-P-R-T-L-Q-E-M-G-D-I-A-H-Q-L-G-N-R-H-L-P-A-Q-F-T-E-T-E-M-L-V-Q-Y-D-Y-L-V-E-D-L-L-K-S-L-G-I-P-Y-V-R-E-D-R-K-V-N-K-A-F-R-H-I-G-H-S-H-D"} +{"text": "### FUNCTION Part of the pathway by which MgrA and SarA control autolysis ### SEQUENCE -M-S-N-K-V-Q-R-F-I-E-A-E-R-E-L-S-Q-L-K-H-W-L-K-T-T-H-K-I-S-I-E-E-F-V-V-L-F-K-V-Y-E-A-E-K-I-S-G-K-E-L-R-D-T-L-H-F-E-M-L-W-D-T-S-K-I-D-V-I-I-R-K-I-Y-K-K-E-L-I-S-K-L-R-S-E-T-D-E-R-Q-V-F-Y-F-Y-S-T-S-Q-K-K-L-L-D-K-I-T-K-E-I-E-V-L-S-V-T-N"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-E-A-R-D-I-L-K-R-P-V-I-T-E-K-S-S-E-A-M-A-E-D-K-Y-T-F-D-V-D-T-R-V-N-K-T-Q-V-K-M-A-V-E-E-I-F-N-V-K-V-A-S-V-N-I-M-N-Y-K-P-K-K-K-R-M-G-R-Y-Q-G-Y-T-N-K-R-R-K-A-I-V-T-L-K-E-G-S-I-D-L-F-N"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-V-A-R-T-I-R-I-A-P-R-K-V-R-L-V-L-D-L-I-R-G-K-N-A-A-E-A-I-A-I-L-K-L-T-N-K-A-S-S-P-V-I-E-K-V-L-M-S-A-L-A-N-A-E-H-N-Y-D-M-N-T-D-E-L-V-V-K-E-A-Y-A-N-E-G-P-T-L-K-R-F-R-P-R-A-Q-G-R-A-S-A-I-N-K-R-T-S-H-I-T-I-V-V-S-D-G-K-E-E-A-K-E-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-L-P-K-R-V-K-Y-R-R-Q-H-R-P-K-T-T-G-R-S-K-G-G-N-Y-V-T-F-G-E-F-G-L-Q-A-T-T-T-S-W-I-T-S-R-Q-I-E-S-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-T-P-Y-T-K-K-P-L-E-V-R-M-G-A-G-K-G-A-V-E-G-W-I-A-V-V-K-P-G-R-I-L-F-E-V-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-T-K-F-V-K-R-E-E-L-G-G-E-T-N-E-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-R-N-D-R-K-V-Y-V-G-K-V-V-S-D-K-M-D-K-T-I-T-V-L-V-E-T-Y-K-T-H-K-L-Y-G-K-R-V-K-Y-S-K-K-Y-K-T-H-D-E-N-N-S-A-K-L-G-D-I-V-K-I-Q-E-T-R-P-L-S-A-T-K-R-F-R-I-V-E-I-V-E-E-S-V-I-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-K-V-A-D-N-S-G-A-R-E-V-L-T-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-V-I-V-C-T-V-K-N-A-T-P-G-G-V-V-K-K-G-D-V-V-K-A-V-I-V-R-T-K-S-G-V-R-R-N-D-G-S-Y-I-K-F-D-E-N-A-C-V-I-I-R-D-D-K-G-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-N-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-E-K-F-N-T-E-V-T-E-N-L-M-K-K-F-N-Y-S-S-V-M-E-V-P-K-I-D-K-I-V-V-N-M-G-V-G-D-A-V-Q-N-S-K-V-L-D-N-A-V-E-E-L-E-L-I-T-G-Q-K-P-L-V-T-K-A-K-K-S-I-A-T-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-I-S-V-S-L-P-R-V-R-D-F-Q-G-V-S-K-K-A-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-D-Y-D-K-V-S-K-V-R-G-M-D-I-V-I-V-T-T-A-N-T-D-E-E-A-R-E-L-L-A-N-F-G-M-P-F-R-K"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-K-I-I-D-I-P-S-D-V-T-V-T-F-D-G-N-H-V-T-V-K-G-P-K-G-E-L-S-R-T-L-N-E-R-M-T-F-K-Q-E-E-N-T-I-E-V-V-R-P-S-D-S-K-E-D-R-T-N-H-G-T-T-R-A-L-L-N-N-M-V-Q-G-V-S-Q-G-Y-V-K-V-L-E-L-V-G-V-G-Y-R-A-Q-M-Q-G-K-D-L-I-L-N-V-G-Y-S-H-P-V-E-I-K-A-E-E-N-I-T-F-S-V-E-K-N-T-V-V-K-V-E-G-I-S-K-E-Q-V-G-A-L-A-S-N-I-R-S-V-R-P-P-E-P-Y-K-G-K-G-I-R-Y-Q-G-E-Y-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-I-D-K-N-K-V-R-L-K-R-H-A-R-V-R-T-N-L-S-G-T-A-E-K-P-R-L-N-V-Y-R-S-N-K-H-I-Y-A-Q-I-I-D-D-N-K-G-V-T-L-A-Q-A-S-S-K-D-S-D-I-A-T-T-A-T-K-V-E-L-A-T-K-V-G-E-A-I-A-K-K-A-A-D-K-G-I-K-E-I-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-S-G-L-E-F"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-Q-T-F-M-A-N-E-S-N-I-E-R-K-W-Y-V-I-D-A-E-G-Q-T-L-G-R-L-S-S-E-V-A-S-I-L-R-G-K-N-K-V-T-Y-T-P-H-V-D-T-G-D-Y-V-I-V-I-N-A-S-K-I-E-F-T-G-N-K-E-T-D-K-V-Y-Y-R-H-S-N-H-P-G-G-I-K-S-I-T-A-G-E-L-R-R-T-N-P-E-R-L-I-E-N-S-I-K-G-M-L-P-S-T-R-L-G-E-K-Q-G-K-K-L-F-V-Y-G-G-A-E-H-P-H-A-A-Q-Q-P-E-N-Y-E-L-R-G"} +{"text": "### FUNCTION Involved in multidrug efflux Confers low level resistance to drugs such as acriflavine, benzalkonium chloride, chlorhexidine gluconate and ethidium bromide ### SEQUENCE -M-I-V-N-Y-L-K-H-K-F-Y-N-L-L-T-T-M-I-V-L-F-I-F-V-L-S-G-A-I-F-L-T-F-L-G-F-G-L-Y-G-L-S-R-I-L-I-Y-F-R-L-G-D-F-T-Y-N-R-S-M-Y-D-N-L-L-Y-Y-G-S-Y-I-I-F-G-Y-F-I-I-F-A-V-E-H-L-M-D-Y-F-R-K-M-L-P-E-N-A-Y-F-R-G-A-T-F-H-L-I-S-Y-T-V-A-T-T-L-F-Y-F-I-I-H-L-N-Y-V-Y-I-N-I-D-F-W-V-I-M-V-I-I-G-F-L-Y-V-C-K-L-Q-F-Y-P-E-S-K-N-L-N-N-R-K"} +{"text": "### FUNCTION Dephosphorylates the phosphotyrosine-containing proteins ### SEQUENCE -M-K-I-L-F-V-C-T-G-N-T-C-R-S-P-L-A-E-S-I-A-K-E-V-M-P-N-H-Q-F-E-S-R-G-I-F-A-V-N-N-Q-G-V-S-N-Y-V-E-D-L-V-E-E-H-H-L-A-E-T-T-L-S-Q-Q-F-T-E-A-D-L-K-A-D-I-I-L-T-M-S-Y-S-H-K-E-L-I-E-A-H-F-G-L-Q-N-H-V-F-T-L-H-E-Y-V-K-E-A-G-E-V-I-D-P-Y-G-G-T-K-E-M-Y-V-H-T-Y-E-E-L-V-S-L-I-L-K-L-K-D-I-I-C"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-T-E-T-A-N-L-F-V-L-G-A-A-G-G-V-E-W-G-T-V-I-V-Q-V-L-T-F-I-V-L-L-A-L-L-K-K-F-A-W-G-P-L-K-D-V-M-D-K-R-E-R-D-I-N-R-D-I-D-D-A-E-Q-A-K-L-N-A-Q-K-L-E-E-E-N-K-Q-K-L-K-E-T-Q-E-E-V-Q-K-I-L-E-D-A-K-V-Q-A-R-Q-Q-Q-E-Q-I-I-H-E-A-N-V-R-A-N-G-M-I-E-T-A-Q-S-E-I-N-S-Q-K-E-R-A-I-A-D-I-N-N-Q-V-S-E-L-S-V-L-I-A-S-K-V-L-R-K-E-I-S-E-Q-D-Q-K-A-L-V-D-K-Y-L-K-E-A-G-D-K"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity ### SEQUENCE -M-L-S-F-S-Q-N-R-S-H-S-L-E-Q-S-L-K-E-G-Y-S-Q-M-A-D-L-N-L-S-L-A-N-E-A-F-P-I-E-C-E-A-C-D-C-N-E-T-Y-L-S-S-N-S-T-N-E"} +{"text": "### FUNCTION Potent plasminogen activator that converts plasminogen into plasmin It forms a 11 complex with plasmin, which in turn activates other plasminogen molecules ### SEQUENCE -M-L-K-R-S-L-L-F-L-T-V-L-L-L-L-F-S-F-S-S-I-T-N-E-V-S-A-S-S-S-F-D-K-G-K-Y-K-K-G-D-D-A-S-Y-F-E-P-T-G-P-Y-L-M-V-N-V-T-G-V-D-S-K-G-N-E-L-L-S-P-H-Y-V-E-F-P-I-K-P-G-T-T-L-T-K-E-K-I-E-Y-Y-V-E-W-A-L-D-A-T-A-Y-K-E-F-R-V-V-E-L-D-P-S-A-K-I-E-V-T-Y-Y-D-K-N-K-K-K-E-E-T-K-S-F-P-I-T-E-K-G-F-V-V-P-D-L-S-E-H-I-K-N-P-G-F-N-L-I-T-K-V-V-I-E-K-K"} +{"text": "### FUNCTION Involved in countering the first line of host defense mechanisms Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine ### SEQUENCE -M-K-K-K-L-A-T-T-V-L-A-L-S-F-L-T-A-G-I-S-T-H-H-H-S-A-K-A-F-T-F-E-P-F-P-T-N-E-E-I-E-S-N-K-K-M-L-E-K-E-K-A-Y-K-E-S-F-K-N-S-G-L-P-T-T-L-G-K-L-D-E-R-L-R-N-Y-L-E-K-G-T-K-N-T-A-Q-F-E-K-M-V-I-L-T-E-N-K-G-Y-Y-T-V-Y-L-N-T-P-L-A-E-D-R-K-N-V-E-L-L-G-K-M-Y-K-T-Y-F-F-K-K-G-E-S-K-S-S-Y-V-I-N-G-P-G-K-T-N-E-Y-A-Y"} +{"text": "### FUNCTION Involved in countering the first line of host defense mechanisms Efficiently inhibits opsonization, phagocytosis and killing of Saureus by human neutrophils Acts by binding and stabilizing human C3 convertases ### SEQUENCE -M-K-I-R-K-S-I-L-A-G-T-L-A-I-V-L-A-S-P-L-V-T-N-L-D-K-N-E-A-Q-A-S-T-S-L-P-T-S-N-E-Y-Q-N-E-K-L-A-N-E-L-K-S-L-L-D-E-L-N-V-N-E-L-A-T-G-S-L-N-T-Y-Y-K-R-T-I-K-I-S-G-L-K-A-M-Y-A-L-K-S-K-D-F-K-K-M-S-E-A-K-Y-Q-L-Q-K-I-Y-N-E-I-D-E-A-L-K-S-K-Y"} +{"text": "### FUNCTION Secreted tyrosine phosphatase that plays a critical role during infection as a bacterial effector protein that counteracts host defenses Required for intramacrophage survival ### SEQUENCE -M-V-D-V-A-F-V-C-L-G-N-I-C-R-S-P-M-A-E-A-I-M-R-Q-R-L-K-D-R-N-I-H-D-I-K-V-H-S-R-G-T-G-S-W-N-L-G-E-P-P-H-E-G-T-Q-K-I-L-N-K-H-N-I-P-F-D-G-M-I-S-E-L-F-E-A-T-D-D-F-D-Y-I-V-A-M-D-Q-S-N-V-D-N-I-K-S-I-N-P-N-L-K-G-Q-L-F-K-L-L-E-F-S-N-M-E-E-S-D-V-P-D-P-Y-Y-T-N-N-F-E-G-V-Y-D-M-V-L-S-S-C-D-N-L-I-D-Y-I-V-K-D-A-N-L-K-E-G"} +{"text": "### FUNCTION Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins May act as a hydrogen peroxide and organic hydroperoxide sensor ### SEQUENCE -M-S-V-E-I-E-S-I-E-H-E-L-E-E-S-I-A-S-L-R-Q-A-G-I-R-I-T-P-Q-R-Q-A-I-L-R-Y-L-I-S-S-H-T-H-P-T-A-D-E-I-Y-Q-A-L-S-P-D-F-P-N-I-S-V-A-T-I-Y-N-N-L-R-V-F-K-D-I-G-I-V-K-E-L-T-Y-G-D-S-S-S-R-F-D-F-N-T-H-N-H-Y-H-I-I-C-E-Q-C-G-K-I-V-D-F-Q-Y-P-Q-L-N-E-I-E-R-L-A-Q-H-M-T-D-F-D-V-T-H-H-R-M-E-I-Y-G-V-C-K-E-C-Q-D-K"} +{"text": "### FUNCTION Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival ### SEQUENCE -M-K-F-N-D-V-Y-N-K-H-H-K-I-I-H-H-L-L-K-K-Y-N-I-S-Y-N-Y-D-E-Y-Y-Q-L-L-L-I-K-M-W-Q-L-S-Q-I-Y-K-P-S-S-K-Q-S-L-S-S-F-L-F-T-R-L-N-Y-Y-L-I-D-L-F-R-Q-Q-N-Q-L-K-D-V-I-L-C-E-N-N-S-P-T-L-T-E-Q-P-T-Y-F-N-E-H-D-L-R-L-Q-D-I-F-K-L-L-N-H-R-E-R-L-W-L-K-L-Y-L-E-G-Y-K-Q-F-E-I-A-E-I-M-S-L-S-L-S-T-I-K-L-I-K-M-S-V-K-R-K-C-Q-H-N-F-N"} +{"text": "### FUNCTION Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence Also, modulates the expression of genes not previously implicated in pathogenesis ### SEQUENCE -M-H-K-L-A-H-T-S-F-G-I-V-G-M-F-V-N-T-C-M-V-A-K-Y-V-I-I-N-W-E-M-F-S-M-K-K-V-N-N-D-T-V-F-G-I-L-Q-L-E-T-L-L-G-D-I-N-S-I-F-S-E-I-E-S-E-Y-K-M-S-R-E-E-I-L-I-L-L-T-L-W-Q-K-G-S-M-T-L-K-E-M-D-R-F-V-E-V-K-P-Y-K-R-T-R-T-Y-N-N-L-V-E-L-E-W-I-Y-K-E-R-P-V-D-D-E-R-T-V-I-I-H-F-N-E-K-L-Q-Q-E-K-V-E-L-L-N-F-I-S-D-A-I-A-S-R-A-T-A-M-Q-N-S-L-N-A-I-I-A-V"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-I-I-E-T-G-G-K-Q-I-K-V-E-E-G-Q-E-I-F-V-E-K-L-D-V-N-E-G-D-T-F-T-F-D-K-V-L-F-V-G-G-D-S-V-K-V-G-A-P-T-V-E-G-A-T-V-T-A-T-V-N-K-Q-G-R-G-K-K-I-T-V-F-T-Y-K-R-R-K-N-S-K-R-K-K-G-H-R-Q-P-Y-T-K-L-T-I-D-K-I-N-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-V-K-T-T-E-K-A-E-A-R-N-I-S-Q-K-S-A-M-R-T-A-V-K-N-A-K-T-A-V-S-N-N-A-D-N-K-N-E-L-V-S-L-A-V-K-L-V-D-K-A-A-Q-S-N-L-I-H-S-N-K-A-D-R-I-K-S-Q-L-M-T-A-N-K"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-D-L-I-N-A-V-A-E-Q-A-D-L-T-K-K-E-A-G-S-A-V-D-A-V-F-E-S-I-Q-N-S-L-A-K-G-E-K-V-Q-L-I-G-F-G-N-F-E-V-R-E-R-A-A-R-K-G-R-N-P-Q-T-G-K-E-I-D-I-P-A-S-K-V-P-A-F-K-A-G-K-A-L-K-D-A-V-K"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-S-D-V-S-L-K-L-S-A-K-D-I-Y-E-K-D-F-E-K-T-M-A-R-G-Y-R-R-E-E-V-D-A-F-L-D-D-I-I-A-D-Y-Q-K-M-A-D-M-N-N-E-V-V-K-L-S-E-E-N-H-K-L-K-K-E-L-E-E-L-R-L-R-V-A-T-S-R-P-Q-D-N-K-S-F-S-S-N-N-T-T-T-N-T-S-S-N-N-V-D-I-L-K-R-I-S-N-L-E-K-A-V-F-G-K"} +{"text": "### FUNCTION Accessory element involved in the expression of sarA and several virulence factors Modulates SarA production and/or function in a strain-dependent manner Affects the transcription of the accessory gene regulator ### SEQUENCE -M-K-Y-L-I-L-S-L-V-A-N-L-L-V-F-G-V-L-S-A-I-G-L-N-I-N-I-L-A-A-M-M-I-V-L-V-I-P-I-M-I-S-G-I-L-F-F-K-T-N-I-D-K-T-Y-I-F-F-N-I-I-F-I-D-F-Y-Y-Y-I-Y-N-V-H-L-M-T-L-P-K-F-N-N-Y-I-K-A-E-M-M-E-L-E-D-I-D-V-L-I-T-S-K-D-F-G-F-D-E-I-L-F-Y-T-L-Y-L-L-L-I-L-I-V-L-Y-Y-L-K-K-Q-V-K-H-K-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-Q-E-R-K-N-E-I-I-K-E-Y-R-V-H-E-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-A-E-I-N-A-V-N-E-H-L-R-T-H-K-K-D-H-H-S-R-R-G-L-L-K-M-V-G-R-R-R-H-L-L-N-Y-L-R-S-K-D-I-Q-R-Y-R-E-L-I-K-S-L-G-I-R-R"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-H-L-A-L-K-D-L-F-S-G-F-F-V-I-D-D-E-E-E-V-E-V-P-D-K-Q-Q-Q-V-N-E-A-P-A-K-E-Q-S-Q-Q-T-T-K-Q-N-A-I-K-S-V-P-Q-K-S-A-S-R-Y-T-T-T-S-E-E-R-N-N-R-M-S-N-Y-S-K-N-N-S-R-N-V-V-T-M-N-N-A-T-P-N-N-A-S-Q-E-S-S-K-M-C-L-F-E-P-R-V-F-S-D-T-Q-D-I-A-D-E-L-K-N-R-R-A-T-L-V-N-L-Q-R-I-D-K-V-S-A-K-R-I-I-D-F-L-S-G-T-V-Y-A-I-G-G-D-I-Q-R-V-G-T-D-I-F-L-C-T-P-D-N-V-E-V-A-G-S-I-T-D-H-I-E-N-M-E-H-S-F-D"} +{"text": "### FUNCTION May be involved in countering the first line of host defense mechanisms Impairs the leukocyte response to FPRL1 agonists by binding directly to host FPRL1 ### SEQUENCE -M-K-K-N-I-T-K-T-I-I-A-S-T-V-I-A-A-G-L-L-T-Q-T-N-D-A-K-A-F-F-S-Y-E-W-K-G-L-E-I-A-K-N-L-A-D-Q-A-K-K-D-D-E-R-I-D-K-L-M-K-E-S-D-K-N-L-T-P-Y-K-A-E-T-V-N-D-L-Y-L-I-V-K-K-L-S-Q-G-D-V-K-K-A-V-V-R-I-K-D-G-G-P-R-D-Y-Y-T-F-D-L-T-R-P-L-E-E-N-R-K-N-I-K-V-V-K-N-G-E-I-D-S-I-Y-W-D"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-A-V-F-K-V-F-Y-Q-H-N-R-D-E-V-I-V-R-E-N-T-Q-S-L-Y-V-E-A-Q-T-E-E-Q-V-R-R-Y-L-K-D-R-N-F-N-I-E-F-I-T-K-L-E-G-A-H-L-D-Y-E-K-E-N-S-E-H-F-N-V-E-I-A-K"} +{"text": "### FUNCTION Catalyzes quinol oxidation with the concomitant reduction of oxygen to water ### SEQUENCE -M-S-T-I-M-K-H-T-V-G-F-I-A-S-I-V-L-T-L-L-A-V-Y-V-T-L-Y-T-S-L-T-F-H-A-K-L-T-I-I-F-G-F-A-F-V-Q-A-G-L-Q-L-L-M-F-M-H-L-T-E-G-K-D-G-R-L-Q-T-F-K-V-I-F-A-L-V-I-T-L-C-F-V-V-G-T-Y-W-V-M-Q-G-G-H-S-S-H-L"} +{"text": "### FUNCTION Specifically inhibits the cysteine protease staphopain B ### SEQUENCE -M-Y-Q-L-Q-F-I-N-L-V-Y-D-T-T-K-L-T-H-L-E-Q-T-N-I-N-L-F-I-G-N-W-S-N-H-Q-L-Q-K-S-I-C-I-R-H-G-D-D-T-S-H-N-Q-Y-H-I-L-F-I-D-T-A-H-Q-R-I-K-F-S-S-I-D-N-E-E-I-T-Y-I-L-D-Y-D-D-T-Q-H-I-L-M-Q-T-S-S-K-Q-G-I-G-T-S-R-P-I-V-Y-E-R-L-V"} +{"text": "### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-A-N-Y-P-Q-L-N-K-E-V-Q-Q-G-E-I-K-V-V-M-H-T-N-K-G-D-M-T-F-K-L-F-P-N-I-A-P-K-T-V-E-N-F-V-T-H-A-K-N-G-Y-Y-D-G-I-T-F-H-R-V-I-N-D-F-M-I-Q-G-G-D-P-T-A-T-G-M-G-G-E-S-I-Y-G-G-A-F-E-D-E-F-S-L-N-A-F-N-L-Y-G-A-L-S-M-A-N-S-G-P-N-T-N-G-S-Q-F-F-I-V-Q-M-K-E-V-P-Q-N-M-L-S-Q-L-A-D-G-G-W-P-Q-P-I-V-D-A-Y-G-E-K-G-G-T-P-W-L-D-Q-K-H-T-V-F-G-Q-I-I-D-G-E-T-T-L-E-D-I-A-N-T-K-V-G-P-Q-D-K-P-L-H-D-V-V-I-E-S-I-D-V-E-E"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-H-T-F-L-I-V-L-L-I-I-D-C-I-A-L-I-T-V-V-L-L-Q-E-G-K-S-S-G-L-S-G-A-I-S-G-G-A-E-Q-L-F-G-K-Q-K-Q-R-G-V-D-L-F-L-N-R-L-T-I-I-L-S-I-L-F-F-V-L-M-I-C-I-S-Y-L-G-M"} +{"text": "### FUNCTION Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase ### SEQUENCE -M-I-R-F-E-I-H-G-D-N-L-T-I-T-D-A-I-R-N-Y-I-E-E-K-I-G-K-L-E-R-Y-F-N-D-V-P-N-A-V-A-H-V-K-V-K-T-Y-S-N-S-A-T-K-I-E-V-T-I-P-L-K-N-V-T-L-R-A-E-E-R-N-D-D-L-Y-A-G-I-D-L-I-N-N-K-L-E-R-Q-V-R-K-Y-K-T-R-I-N-R-K-S-R-D-R-G-D-Q-E-V-F-V-A-E-L-Q-E-M-Q-E-T-Q-V-D-N-D-A-Y-D-D-N-E-I-E-I-I-R-S-K-E-F-S-L-K-P-M-D-S-E-E-A-V-L-Q-M-N-L-L-G-H-D-F-F-V-F-T-D-R-E-T-D-G-T-S-I-V-Y-R-R-K-D-G-K-Y-G-L-I-Q-T-S-E-Q"} +{"text": "### FUNCTION Regulatory protein involved in autolytic activity, multidrug resistance and virulence ### SEQUENCE -M-S-D-Q-H-N-L-K-E-Q-L-C-F-S-L-Y-N-A-Q-R-Q-V-N-R-Y-Y-S-N-K-V-F-K-K-Y-N-L-T-Y-P-Q-F-L-V-L-T-I-L-W-D-E-S-P-V-N-V-K-K-V-V-T-E-L-A-L-D-T-G-T-V-S-P-L-L-K-R-M-E-Q-V-D-L-I-K-R-E-R-S-E-V-D-Q-R-E-V-F-I-H-L-T-D-K-S-E-T-I-R-P-E-L-S-N-A-S-D-K-V-A-S-A-S-S-L-S-Q-D-E-V-K-E-L-N-R-L-L-G-K-V-I-H-A-F-D-E-T-K-E-K"} +{"text": "### FUNCTION Involved in the regulation of virulence genes Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb Binds directly to the agr promoter region ### SEQUENCE -M-N-T-E-K-L-E-T-L-L-G-F-Y-K-Q-Y-K-A-L-S-E-Y-I-D-K-K-Y-K-L-S-L-N-D-L-A-V-L-D-L-T-M-K-H-C-K-D-E-K-V-L-M-Q-S-F-L-K-T-A-M-D-E-L-D-L-S-R-T-K-L-L-V-S-I-R-R-L-I-E-K-E-R-L-S-K-V-R-S-S-K-D-E-R-K-I-Y-I-Y-L-N-N-D-D-I-S-K-F-N-A-L-F-E-D-V-E-Q-F-L-N-I"} +{"text": "### FUNCTION Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines Requires NADPH, but not NADH, as an electron donor for its activity ### SEQUENCE -M-K-G-L-I-I-I-G-S-A-Q-V-N-S-H-T-S-A-L-A-R-Y-L-T-E-H-F-K-T-H-D-I-E-A-E-I-F-D-L-A-E-K-P-L-N-Q-L-D-F-S-G-T-T-P-S-I-D-E-I-K-Q-N-M-K-D-L-K-E-K-A-M-A-A-D-F-L-I-L-G-T-P-N-Y-H-G-S-Y-S-G-I-L-K-N-A-L-D-H-L-N-M-D-Y-F-K-M-K-P-V-G-L-I-G-N-S-G-G-I-V-S-S-E-P-L-S-H-L-R-V-I-V-R-S-L-L-G-I-A-V-P-T-Q-I-A-T-H-D-S-D-F-A-K-N-E-D-G-S-Y-Y-L-N-D-S-E-F-Q-L-R-A-R-L-F-V-D-Q-I-V-S-F-V-N-N-S-P-Y-E-H-L-K"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-R-N-E-I-F-E-K-I-M-R-L-E-M-N-V-N-Q-L-S-K-E-T-S-E-L-K-A-H-A-V-E-L-V-E-E-N-V-A-L-Q-L-E-N-D-N-L-K-K-V-L-G-N-D-E-P-T-T-I-D-T-A-N-S-K-P-A-K-A-V-K-K-P-L-P-S-K-D-N-L-A-I-L-Y-G-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-F-C-L-E-V-L-S-D"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-S-K-L-I-D-S-F-M-K-L-P-G-I-G-P-K-T-A-Q-R-L-A-F-H-T-L-D-M-K-E-D-D-V-V-Q-F-A-K-A-L-V-D-V-K-R-E-L-T-Y-C-S-V-C-G-H-I-T-E-N-D-P-C-Y-I-C-E-D-K-Q-R-D-R-S-V-I-C-V-V-E-D-D-K-D-V-I-A-M-E-K-M-R-E-Y-K-G-L-Y-H-V-L-H-G-S-I-S-P-M-D-G-I-G-P-E-D-I-N-I-P-S-L-I-E-R-L-K-S-D-E-V-S-E-L-I-L-A-M-N-P-N-L-E-G-E-S-T-A-M-Y-I-S-R-L-V-K-P-I-G-I-K-V-T-R-L-A-Q-G-L-S-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-I-A-G-R-T-E-M"} +{"text": "### FUNCTION Virulence factor that is important for the establishment of infection in the host EsxB is required for EsxA synthesis as well as secretion ### SEQUENCE -M-G-G-Y-K-G-I-K-A-D-G-G-K-V-N-Q-A-K-Q-L-A-A-K-I-A-K-D-I-E-A-C-Q-K-Q-T-Q-Q-L-A-E-Y-I-E-G-S-D-W-E-G-Q-F-A-N-K-V-K-D-V-L-L-I-M-A-K-F-Q-E-E-L-V-Q-P-M-A-D-H-Q-K-A-I-D-N-L-S-Q-N-L-A-K-Y-D-T-L-S-I-K-Q-G-L-D-R-V-N-P"} +{"text": "### FUNCTION Implements its pathogenic function during infection ### SEQUENCE -M-N-F-N-D-I-E-T-M-V-K-S-K-F-K-D-I-K-K-H-A-E-E-I-A-H-E-I-E-V-R-S-G-Y-L-R-K-A-E-Q-Y-K-R-L-E-F-N-L-S-I-A-L-D-D-V-E-S-T-A-K-D-V-Q-T-A-K-S-S-A-N-K-D-S-V-S-V-K-G-K-A-P-N-T-L-Y-I-E-K-R-N-L-M-K-Q-K-L-E-M-L-G-E-D-I-D-K-N-K-E-S-L-Q-K-A-K-G-I-A-G-E-K-A-S-E-Y-F-N-K-A-M-N"} +{"text": "### FUNCTION Component of the ESAT-6 secretion system Required for the secretion of EsxA and EsxB ### SEQUENCE -M-L-M-N-S-V-I-A-L-T-F-L-T-A-S-S-N-N-G-G-L-N-I-D-V-Q-Q-E-E-E-K-R-I-N-N-D-L-N-Q-Y-D-T-T-L-F-N-K-D-S-K-E-V-N-D-A-I-A-K-Q-K-K-E-R-Q-Q-Q-I-K-N-D-M-F-Q-N-Q-A-S-H-S-T-R-L-N-E-T-K-K-V-L-F-S-K-S-N-L-E-K-T-S-E-S-D-K-S-P-Y-I-Q-N-K-Q-E-K-K-I-F-P-Y-I-L-M-S-V-G-A-F-L-T-L-G-F-V-I-F-S-I-H-K-G-R-R-T-K-N-E-S-A-R-K-S-N-I"} +{"text": "### FUNCTION Virulence factor that is important for the establishment of infection in the host EsxA is required for EsxB synthesis as well as secretion ### SEQUENCE -M-A-M-I-K-M-S-P-E-E-I-R-A-K-S-Q-S-Y-G-Q-G-S-D-Q-I-R-Q-I-L-S-D-L-T-R-A-Q-G-E-I-A-A-N-W-E-G-Q-A-F-S-R-F-E-E-Q-F-Q-Q-L-S-P-K-V-E-K-F-A-Q-L-L-E-E-I-K-Q-Q-L-N-S-T-A-D-A-V-Q-E-Q-D-Q-Q-L-S-N-N-F-G-L-Q"} +{"text": "### FUNCTION Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage ### SEQUENCE -M-L-Q-S-I-P-A-L-P-V-G-D-I-K-K-S-I-G-F-Y-C-D-K-L-G-F-T-L-V-H-H-E-D-G-F-A-V-L-M-C-N-E-V-R-I-H-L-W-E-A-S-D-E-G-W-R-S-R-S-N-D-S-P-V-C-T-G-A-E-S-F-I-A-G-T-A-S-C-R-I-E-V-E-G-I-D-E-L-Y-Q-H-I-K-P-L-G-I-L-H-P-N-T-S-L-K-D-Q-W-W-D-E-R-D-F-A-V-I-D-P-D-N-N-L-I-S-F-F-Q-Q-I-K-S"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-V-K-L-I-C-V-G-K-L-K-E-R-Y-L-K-D-G-I-S-E-Y-Q-K-R-L-S-R-F-C-Q-F-E-M-I-E-L-T-D-E-R-T-P-D-K-A-S-F-A-D-N-Q-L-I-M-S-K-E-A-Q-R-I-H-K-K-I-G-E-R-D-F-V-I-A-L-A-I-E-G-K-Q-F-P-S-E-T-F-S-E-L-I-S-G-V-T-V-K-G-Y-S-T-I-T-F-I-I-G-G-S-L-G-L-D-S-I-I-K-K-R-A-N-M-L-M-S-F-G-L-L-T-L-P-H-Q-L-M-R-L-V-L-T-E-Q-I-Y-R-A-F-M-I-T-Q-G-S-P-Y-H-K"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-M-E-R-Q-Q-Q-I-K-R-I-I-Q-A-E-H-I-G-T-Q-E-D-I-K-N-H-L-Q-K-E-G-I-V-V-T-Q-A-T-L-S-R-D-L-R-E-I-G-L-L-K-L-R-D-E-Q-G-K-L-Y-Y-S-L-S-E-P-V-A-T-P-F-S-P-E-V-R-F-Y-V-L-K-V-D-R-A-G-F-M-L-V-L-H-T-N-L-G-E-A-D-V-L-A-N-L-I-D-N-D-A-I-E-D-I-L-G-T-I-A-G-A-D-T-L-L-V-I-C-R-D-E-E-I-A-K-R-F-E-K-D-L-A-A-G-L"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-M-G-L-D-V-G-S-K-T-V-G-V-A-I-S-D-P-L-G-F-T-A-Q-G-L-E-I-I-K-I-D-E-E-K-A-E-F-G-F-T-R-L-E-E-L-V-K-Q-Y-Q-V-E-Q-F-V-I-G-L-P-K-N-M-N-N-T-N-G-P-R-V-D-A-S-I-T-Y-G-N-H-I-E-H-L-F-G-L-P-V-H-Y-Q-D-E-R-L-T-T-V-E-A-K-R-M-L-I-E-Q-A-D-I-S-R-G-K-R-K-K-V-I-D-K-L-A-A-Q-L-I-L-Q-N-Y-L-N-R-N-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-N-E-I-I-A-Q-Y-A-R-H-E-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-W-E-I-N-H-L-N-S-H-I-K-Q-H-K-K-D-H-A-T-Y-R-G-L-M-K-K-I-G-H-R-R-N-L-L-A-Y-L-R-R-T-D-V-N-R-Y-R-E-L-I-Q-S-L-G-L-R-R"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-F-Y-Q-E-T-K-D-Q-S-P-R-R-E-S-T-K-A-L-Y-L-N-I-D-A-T-D-E-L-D-G-R-I-K-A-R-R-L-V-E-D-N-T-Y-Y-N-V-E-F-I-E-L-L-S-D-K-H-L-D-Y-E-K-E-T-G-V-F-E-L-T-E-F"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-T-N-S-F-Q-N-S-R-R-D-L-R-E-R-A-F-Q-A-L-F-N-I-E-M-G-A-E-L-L-A-A-S-Q-F-A-Y-G-Y-D-K-V-T-G-E-D-A-Q-V-L-E-L-P-I-F-L-L-S-L-V-T-G-V-N-N-H-K-E-E-L-D-N-L-I-S-T-H-L-K-K-G-W-S-L-E-R-L-T-L-T-D-K-T-L-L-R-L-G-L-F-E-I-K-Y-F-D-E-T-P-D-R-V-A-L-N-E-I-I-E-V-A-K-K-Y-S-D-E-T-S-A-K-F-I-N-G-L-L-S-Q-Y-V-S-G-A-P-S-A-N-K-S"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-V-G-H-G-I-D-L-Q-E-I-S-A-I-E-K-V-Y-Q-R-N-P-R-F-A-Q-K-I-L-T-E-Q-E-L-A-I-F-E-S-F-P-Y-K-R-R-L-N-Y-L-A-G-R-W-S-G-K-E-A-F-A-K-A-I-G-T-G-I-G-R-L-T-F-Q-D-I-E-I-L-N-D-V-R-G-C-P-I-L-T-K-S-P-F-K-G-N-S-F-I-S-I-S-H-S-G-N-Y-V-Q-A-S-V-I-L-E-D-K-K"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-T-S-I-I-Y-S-P-K-D-I-F-E-Q-E-F-K-T-S-M-R-G-F-D-K-K-E-V-D-E-F-L-D-N-V-I-K-D-Y-E-N-F-N-A-Q-I-E-A-L-K-A-E-N-E-A-L-K-K-A-K-F-Q-A-R-N-T-V-S-A-T-V-Q-Q-P-V-P-Q-P-T-R-V-A-Q-S-A-T-N-F-D-I-L-K-R-I-S-K-L-E-K-E-V-F-G-K-Q-I-I-E"} +{"text": "### FUNCTION Regulates the transcription of the arc operon, involved in arginine catabolism ### SEQUENCE -M-N-K-K-E-T-R-H-Q-L-I-R-S-L-I-S-E-T-T-I-H-T-Q-Q-E-L-Q-E-R-L-Q-K-N-G-I-T-I-T-Q-A-T-L-S-R-D-M-K-E-L-N-L-V-K-V-T-S-G-N-D-T-H-Y-E-A-L-A-I-S-Q-T-R-W-E-H-R-L-R-F-Y-M-E-D-A-L-V-M-L-K-I-V-Q-H-Q-I-I-L-K-T-L-P-G-L-A-Q-S-F-G-S-I-L-D-A-M-Q-I-P-E-I-V-A-T-V-C-G-D-D-T-C-L-I-V-C-E-D-N-E-Q-A-K-A-C-Y-E-T-L-S-H-Y-T-P-P-F-F-F-S-N-K"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-D-I-K-Q-T-A-V-A-G-S-L-E-S-S-D-L-M-I-T-V-S-P-N-D-E-Q-T-I-T-I-T-L-D-S-S-V-E-K-Q-F-G-N-H-I-R-Q-L-I-H-Q-T-L-V-N-L-K-V-T-A-A-K-V-E-A-V-D-K-G-A-L-D-C-T-I-Q-A-R-T-I-A-A-V-H-R-A-A-G-I-D-Q-Y-D-W-K-E-I-D-S-W-N-V"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-A-E-E-Q-V-L-N-T-H-N-A-S-I-L-L-S-A-A-N-K-S-H-Y-P-Q-D-D-L-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-I-L-G-R-K-N-L-A-R-T-S-S-K-P-G-K-T-Q-L-L-N-F-F-N-I-D-D-K-L-R-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-S-E-R-A-K-W-G-K-M-I-E-E-Y-L-T-S-R-D-N-L-R-A-V-V-S-L-V-D-L-R-H-A-P-S-K-E-D-I-Q-M-Y-D-F-L-K-Y-Y-D-I-P-V-I-V-V-A-T-K-A-D-K-I-P-R-G-K-W-N-K-H-E-S-V-V-K-K-A-L-N-F-D-K-S-D-T-F-I-V-F-S-S-V-E-R-I-G-I-D-D-S-W-D-A-I-L-E-Q-V"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-K-T-K-E-I-V-D-D-V-T-M-K-R-A-I-T-R-I-T-Y-E-I-I-E-R-N-K-Q-L-D-N-V-V-L-A-G-I-K-T-R-G-V-F-L-A-R-R-I-Q-E-R-L-H-Q-L-E-G-L-D-L-P-I-G-E-L-D-I-K-P-F-R-D-D-M-R-V-E-E-D-T-T-L-M-S-V-D-I-T-G-K-D-V-I-L-I-D-D-V-L-Y-T-G-R-T-I-R-A-A-I-D-N-L-V-S-L-G-R-P-A-R-V-S-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-S-V-E-E-I-V-V-E-V-V-E-V-D-G-R-D-R-V-S-I-I-D-S-T"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-T-Y-A-I-I-K-T-G-G-K-Q-V-K-V-E-V-G-Q-A-I-Y-V-E-K-I-D-A-E-A-G-A-E-V-T-F-N-E-V-V-L-V-G-G-D-K-T-V-V-G-T-P-V-V-E-G-A-T-V-V-G-T-V-E-K-Q-G-K-Q-K-K-V-V-T-F-K-Y-K-P-K-K-G-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-N-A-I-N-A"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-T-Q-M-T-V-Q-V-V-T-P-D-G-I-K-Y-D-H-H-A-K-F-I-S-V-T-T-P-D-G-E-M-G-I-L-P-N-H-I-N-L-I-A-P-L-Q-V-H-E-M-K-I-R-R-G-G-E-D-E-K-V-D-W-I-A-I-N-G-G-I-I-E-I-K-D-N-V-V-T-I-V-A-D-S-A-E-R-D-R-D-I-D-V-S-R-A-E-R-A-K-L-R-A-E-R-E-I-A-Q-A-E-T-T-H-N-I-D-E-V-R-R-A-K-V-A-L-R-R-A-L-N-R-I-N-V-S-K-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-T-K-K-E-Q-A-L-I-E-Q-Y-A-K-S-L-V-E-V-A-S-E-H-H-S-L-D-A-L-Q-A-D-V-L-A-I-L-E-T-F-V-T-T-N-L-D-Q-S-L-S-S-Q-A-V-P-H-A-E-K-I-K-L-L-T-L-L-K-G-N-N-S-V-Y-M-N-N-F-L-N-L-I-L-Q-N-E-R-E-A-Y-L-Y-Q-M-L-Q-A-V-L-N-E-I-A-I-V-S-N-Q-Y-D-V-T-V-T-S-S-L-P-L-T-E-E-Q-K-S-R-V-R-A-V-V-A-K-K-F-A-V-T-A-G-R-L-I-E-K-V-D-P-S-L-I-G-G-F-I-I-S-V-N-N-K-V-I-D-T-S-I-R-R-Q-L-Q-A-F-K-M-N-L-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-I-T-F-G-E-L-V-G-N-F-I-L-V-T-G-S-V-I-V-L-L-L-L-I-K-K-F-A-W-G-A-I-E-S-I-L-Q-T-R-S-Q-Q-I-S-R-D-I-D-Q-A-E-Q-S-R-L-S-A-Q-Q-L-E-A-K-S-Q-A-N-L-D-A-S-R-L-Q-A-S-K-I-I-S-D-A-K-E-I-G-Q-L-Q-G-D-K-L-V-A-E-A-T-D-E-A-K-R-L-K-E-K-A-L-T-D-I-E-Q-S-K-S-D-A-I-S-A-V-K-T-E-M-S-D-L-T-V-L-L-A-E-K-I-M-G-A-N-L-D-K-T-A-Q-S-Q-L-I-D-S-Y-L-D-D-L-G-E-A"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-G-E-G-H-I-L-A-Q-N-K-K-A-R-H-D-Y-H-I-V-E-T-V-E-A-G-I-V-L-T-G-T-E-I-K-S-V-R-A-A-R-I-Q-L-K-D-G-F-A-Q-I-K-N-G-E-A-W-L-V-N-V-H-I-A-P-F-E-Q-G-N-I-W-N-A-D-P-E-R-T-R-K-L-L-L-K-K-R-E-I-T-H-L-A-N-E-L-K-G-S-G-M-T-L-V-P-L-K-V-Y-L-K-D-G-F-A-K-V-L-I-G-L-A-K-G-K-H-E-Y-D-K-R-E-T-I-K-R-R-D-Q-E-R-D-I-K-K-Q-M-K-H-Y-N-A-R"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-R-A-I-F-A-G-G-C-F-W-C-M-V-Q-P-F-E-E-Q-A-G-I-L-S-V-R-S-G-Y-T-G-G-H-L-P-N-P-S-Y-E-Q-V-C-A-K-T-T-G-H-T-E-A-V-E-I-I-F-D-P-K-Q-I-A-Y-K-D-L-V-E-L-Y-W-T-Q-T-D-P-T-D-A-F-G-Q-F-E-D-R-G-D-N-Y-R-P-V-I-Y-Y-T-T-E-R-Q-K-E-I-A-E-Q-S-K-A-N-L-Q-A-S-G-R-F-D-Q-P-I-V-T-T-I-E-P-A-E-P-F-Y-L-A-E-D-Y-H-Q-G-F-Y-K-K-N-P-K-R-Y-A-Q-S-S-A-I-R-H-Q-F-L-E-E-N-W-S"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-S-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-Q-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-K-Q-T-N-N-L-I-T-E-R-T-H-P-C-H-K-P-M-R-H-T-S-H"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-T-Y-R-V-K-R-E-K-D-F-Q-A-I-F-K-D-G-K-S-T-A-N-R-K-F-V-I-Y-H-L-N-R-G-Q-D-H-F-R-V-G-I-S-V-G-K-K-I-G-N-A-V-T-R-N-A-V-K-R-K-I-R-H-V-I-M-A-L-G-H-Q-L-K-S-E-D-F-V-V-I-A-R-K-G-V-E-S-L-E-Y-Q-E-L-Q-Q-N-L-H-H-V-L-K-L-A-Q-L-L-E-K-G-F-E-S-E-E-K-H"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-P-T-R-K-R-R-V-K-K-D-I-E-S-G-V-A-H-I-H-A-T-F-N-N-T-I-V-M-I-T-D-V-H-G-N-A-L-A-W-S-S-A-G-A-L-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-A-A-A-K-S-A-Q-E-H-G-L-K-T-V-E-V-T-V-K-G-P-G-S-G-R-E-S-A-I-R-A-L-A-A-A-G-L-E-V-T-A-I-R-D-V-T-P-V-P-H-N-G-A-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-A-A-E-G-S-R-K-V-R-N-R-V-G-R-G-T-S-S-G-N-G-K-T-S-G-R-G-Q-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-I-P-K-R-G-F-T-N-I-N-T-K-E-Y-A-L-V-N-L-D-Q-L-N-V-F-D-D-G-T-E-V-T-P-A-I-L-K-D-A-G-I-V-R-A-E-K-S-G-V-K-V-L-G-N-G-E-L-T-K-K-L-T-V-K-A-A-K-F-S-K-S-A-E-A-A-I-I-A-K-G-G-S-I-E-V-I"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-I-R-Q-K-R-H-R-R-V-R-G-K-L-S-G-T-A-D-R-P-R-L-N-V-F-R-S-N-T-G-I-Y-A-Q-V-I-D-D-V-A-G-V-T-L-A-S-A-S-T-L-D-K-D-V-S-K-G-T-K-T-E-Q-A-V-V-V-G-K-L-V-A-E-R-A-V-A-K-G-I-S-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-N-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-V-I-T-M-P-A-G-V-E-L-T-N-N-N-N-V-I-T-V-K-G-P-K-G-E-L-T-R-E-F-N-K-N-I-E-I-K-V-E-G-T-E-I-T-V-V-R-P-N-D-S-K-E-M-K-T-I-H-G-T-T-R-A-N-L-N-N-M-V-V-G-V-S-E-G-F-K-K-D-L-E-M-K-G-V-G-Y-R-A-Q-L-Q-G-T-K-L-V-L-S-V-G-K-S-H-Q-D-E-V-E-A-P-E-G-I-T-F-T-V-A-N-P-T-S-I-S-V-E-G-I-N-K-E-V-V-G-Q-T-A-A-Y-I-R-S-L-R-S-P-E-P-Y-K-G-K-G-I-R-Y-V-G-E-Y-V-R-L-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-N-R-L-K-E-K-Y-T-N-E-V-I-P-A-L-T-E-K-F-N-Y-T-S-V-M-A-V-P-K-V-E-K-I-V-L-N-M-G-V-G-D-A-V-S-N-A-K-N-L-E-K-A-A-A-E-L-A-L-I-S-G-Q-K-P-L-I-T-K-A-K-K-S-I-A-G-F-R-L-R-E-G-V-A-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-V-S-V-S-L-P-R-V-R-D-F-H-G-V-P-T-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-S-F-D-D-V-D-K-V-R-G-L-D-I-V-I-V-T-T-A-N-T-D-E-E-S-R-E-L-L-K-G-L-G-M-P-F-A-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-F-V-K-K-G-D-K-V-R-V-I-A-G-K-D-K-G-T-E-A-V-V-L-K-A-L-P-K-V-N-K-V-I-V-E-G-V-G-M-I-K-K-H-Q-K-P-N-T-E-N-P-Q-G-A-I-V-E-K-E-A-P-I-H-V-S-N-V-Q-V-L-D-K-N-G-V-A-G-R-I-G-Y-K-V-V-D-G-K-K-V-R-Y-S-K-K-S-G-E-V-L-D"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-K-V-A-D-N-S-G-A-R-E-I-L-T-I-K-V-L-G-G-S-G-R-K-F-A-N-I-G-D-V-I-V-A-S-V-K-Q-A-T-P-G-G-A-V-K-K-G-D-V-V-K-A-V-I-V-R-T-K-T-G-A-R-R-P-D-G-S-Y-I-K-F-D-D-N-A-A-V-I-I-R-D-D-K-T-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-G-Y-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-N-Q-R-K-T-L-Y-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-K-R-N-H-P-V-Y-G-K-R-I-N-Y-S-K-K-Y-K-A-H-D-E-N-N-V-A-K-E-G-D-I-V-R-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-V-V-E-K-A-V-I-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-H-R-R-E-F-R-G-K-M-R-G-E-A-K-G-G-K-E-V-S-F-G-E-Y-G-L-Q-A-T-T-S-H-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-A-K-A-I-G-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-P-V-K-R-G-K-V-M-F-E-I-A-G-V-S-E-E-I-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-C-K-F-V-K-R-E-A-E"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-L-Y-D-V-I-K-K-P-V-I-T-E-K-S-M-I-A-L-E-A-G-K-Y-T-F-E-V-D-T-R-A-H-K-L-L-I-K-Q-A-V-E-A-A-F-D-G-V-K-V-A-S-V-N-T-V-N-V-K-P-K-A-K-R-V-G-R-Y-T-G-F-T-S-K-T-K-K-A-I-I-T-L-T-A-D-S-K-A-I-E-L-F-A-A-E-A-E"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-K-M-I-V-G-L-G-N-P-G-S-K-Y-E-K-T-K-H-N-I-G-F-M-A-I-D-N-I-V-K-N-L-D-V-T-F-T-D-D-K-N-F-K-A-Q-I-G-S-T-F-I-N-H-E-K-V-Y-F-V-K-P-T-T-F-M-N-N-S-G-I-A-V-K-A-L-L-T-Y-Y-N-I-D-I-T-D-L-I-V-I-Y-D-D-L-D-M-E-V-S-K-L-R-L-R-S-K-G-S-A-G-G-H-N-G-I-K-S-I-I-A-H-I-G-T-Q-E-F-N-R-I-K-V-G-I-G-R-P-L-K-G-M-T-V-I-N-H-V-M-G-Q-F-N-T-E-D-N-I-A-I-S-L-T-L-D-R-V-V-N-A-V-K-F-Y-L-Q-E-N-D-F-E-K-T-M-Q-K-F-N-G"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-T-D-T-I-A-P-E-A-T-P-E-G-A-E-A-G-Q-A-G-I-R-I-L-A-Q-F-V-R-D-F-S-F-E-N-P-L-A-P-D-A-L-R-A-G-A-A-Q-P-A-I-D-M-G-V-E-M-N-A-R-G-R-A-D-G-L-F-E-V-D-L-K-L-S-A-R-A-E-R-E-G-Q-A-V-F-H-V-E-V-V-Y-G-G-L-F-H-I-A-G-I-A-E-E-D-L-E-P-V-L-L-I-E-C-P-R-F-L-F-P-Y-A-R-R-L-I-S-D-V-T-A-E-G-G-F-P-P-F-L-I-D-P-I-D-F-A-G-V-Y-A-A-R-K-A-Q-A-E-G-Q-Q-V-G-N-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-S-A-I-P-A-G-L-A-I-R-F-K-R-W-E-G-N-A-D-L-P-V-P-A-Y-A-T-V-G-A-A-G-F-D-L-R-A-H-V-P-D-D-A-P-I-V-L-K-P-G-A-R-C-M-A-P-T-G-F-S-V-A-I-P-D-G-Y-E-M-Q-V-R-P-R-S-G-L-A-L-K-N-G-V-T-V-V-N-A-P-G-T-V-D-S-D-Y-R-G-Q-V-C-V-L-L-I-N-L-G-E-E-D-F-T-I-R-R-G-D-R-I-A-Q-G-V-I-A-A-A-P-Q-W-P-L-V-E-V-E-D-L-D-A-T-E-R-G-A-G-G-F-G-S-T-G-V"} +{"text": "### FUNCTION Antioxidant protein with alkyl hydroperoxidase activity Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity ### SEQUENCE -M-S-I-E-A-L-R-A-R-L-P-D-Y-A-H-D-L-G-T-N-L-A-L-L-V-D-D-P-A-L-D-P-E-A-R-W-G-C-F-V-A-S-A-C-A-V-G-E-P-Q-T-L-R-A-I-D-A-A-A-T-A-A-G-L-T-A-E-A-N-R-A-A-R-K-A-A-A-M-M-A-M-T-N-V-Y-F-R-A-V-H-L-M-E-G-A-A-Y-Q-A-L-P-C-R-L-R-L-N-R-L-A-H-A-G-A-R-G-V-T-Y-D-L-S-C-V-A-V-S-A-I-N-G-C-G-A-C-L-D-S-H-E-A-D-L-R-G-R-G-V-E-P-T-Q-I-Q-A-A-L-R-I-A-A-V-V-S-A-V-A-R-T-L-A-A-E-A-A-L-H-P-Q-N-L-E-I"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-R-T-V-V-D-Y-G-A-A-I-A-F-G-V-A-Y-F-V-T-K-D-F-Q-K-A-T-W-V-L-V-A-A-S-A-A-A-L-A-I-G-Y-A-V-E-R-R-L-A-M-L-P-L-F-F-G-G-M-A-L-V-F-G-T-L-G-L-I-F-G-S-D-V-F-V-K-I-K-V-T-V-I-N-L-A-L-A-S-F-L-V-G-G-V-L-L-K-R-Q-P-L-K-V-I-M-G-E-A-L-H-L-P-D-A-A-W-R-T-L-T-L-R-Y-G-A-Y-F-A-F-V-A-I-I-N-E-V-V-R-N-T-Q-D-T-D-T-W-V-K-F-R-L-A-L-L-P-V-A-L-V-F-V-A-T-Q-L-P-F-M-M-K-H-M-A-K-G-D-D-A-K-A-V-E-P-P-D-A-G-F"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-A-V-S-P-D-D-P-L-I-L-V-G-R-V-A-G-G-F-G-V-R-G-E-V-R-I-T-T-Y-T-E-D-P-L-S-I-A-G-F-K-A-L-K-R-Q-D-G-S-P-A-L-T-I-A-S-A-R-K-T-K-D-G-V-V-C-R-C-P-G-V-E-T-K-E-A-A-D-A-L-R-G-L-R-L-Y-V-P-R-S-A-L-P-E-P-D-D-D-E-F-Y-L-T-D-L-V-G-L-T-V-R-H-I-Q-T-D-Q-L-L-G-R-V-K-S-V-Q-N-F-G-A-G-D-I-L-E-I-T-P-D-L-G-G-P-T-W-Y-L-P-F-T-R-A-A-V-P-E-V-R-V-S-E-G-L-I-L-A-D-P-P-A-L-V-G-D-H-E-G-P-E-E-K-G-L-D-E-N-E-E-L-G-D-R-D"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-I-K-S-E-L-I-A-R-L-A-N-E-N-P-H-L-T-Q-K-D-V-E-R-V-V-G-V-I-L-E-R-M-I-G-A-L-E-D-G-G-R-V-E-L-R-G-F-G-A-L-S-V-R-S-R-P-A-R-T-G-R-N-P-R-T-G-E-A-V-D-V-R-A-K-H-V-P-F-F-K-S-G-K-E-L-R-A-R-L-N-A-D-G-D-E"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-V-V-K-E-F-R-E-F-I-A-R-G-N-V-I-D-L-A-V-G-V-I-I-G-A-A-F-N-G-I-V-K-S-L-V-D-Q-V-I-M-P-P-I-G-L-L-T-G-G-L-D-F-S-K-L-E-W-V-L-R-P-E-D-P-A-S-E-A-I-E-K-V-A-I-Q-Y-G-A-F-V-N-T-V-I-Q-F-F-I-V-A-T-V-V-F-L-L-V-K-L-V-N-E-I-R-R-Q-D-A-A-E-P-A-P-A-A-P-P-A-P-T-A-E-E-T-L-L-T-E-I-R-D-L-L-A-K-K-G"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-D-E-T-K-A-T-D-A-G-Q-R-Y-A-Q-S-L-F-E-L-T-I-E-N-G-S-L-Q-K-V-E-A-D-L-K-S-L-K-A-M-V-A-D-S-A-D-L-R-R-L-I-A-S-P-A-F-S-A-E-D-K-G-K-G-L-T-A-V-A-K-K-A-G-F-Q-P-L-T-T-K-F-L-G-L-V-A-A-N-G-R-T-G-D-L-L-G-A-I-S-A-F-V-E-L-S-A-K-H-R-G-V-V-T-A-E-V-V-S-A-A-A-L-S-P-A-Q-L-K-G-V-Q-T-A-L-A-Q-A-L-G-K-T-P-E-V-S-T-R-V-D-P-S-L-L-G-G-L-K-V-R-V-G-S-R-L-F-D-A-S-L-R-S-K-L-D-S-L-K-F-A-L-K-R-A"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-K-L-H-F-S-L-V-A-P-E-R-E-L-F-S-G-E-V-D-M-V-Q-A-P-G-A-E-G-D-F-G-V-L-A-N-H-A-P-F-M-T-T-L-R-E-G-K-V-T-V-K-D-G-A-T-T-K-V-F-D-I-Q-G-G-F-A-D-V-G-P-E-G-L-T-I-L-A-E-H-A-V-E-A-A"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-T-E-L-D-H-P-Q-H-R-P-N-V-G-V-V-L-F-H-P-D-G-R-V-W-L-G-R-R-H-R-Q-A-P-P-Y-N-W-Q-F-P-Q-G-G-V-D-E-G-E-D-L-E-V-A-A-R-R-E-L-A-E-E-T-G-V-T-S-V-E-L-L-G-R-T-E-G-W-I-T-Y-D-F-P-P-E-V-M-A-N-P-K-H-A-R-G-W-R-G-Q-K-Q-V-W-F-A-Y-R-F-V-G-E-E-S-E-I-D-L-E-A-D-E-H-I-E-F-D-A-W-R-W-G-R-L-D-E-T-P-E-L-I-V-P-F-K-R-G-V-Y-E-A-V-V-A-A-F-Q-G-F-A-R-G-D-S-P-V-R-R-R-E-G-E-N"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-M-K-I-T-I-L-T-V-G-K-L-G-R-M-V-E-A-Q-L-A-L-D-Y-A-S-R-A-T-A-S-G-R-A-L-A-L-G-P-V-D-I-L-E-V-E-A-R-K-P-G-K-A-A-E-A-E-V-L-R-P-H-L-E-G-A-Y-V-V-A-C-D-E-H-G-K-A-W-K-S-R-A-F-A-D-H-L-A-R-L-R-D-D-G-N-R-R-V-V-F-L-I-G-G-A-D-G-L-D-P-S-I-L-A-A-A-N-E-T-M-A-F-G-V-Q-T-W-P-H-A-L-A-R-A-M-L-A-E-Q-I-Y-R-A-A-T-I-L-S-G-S-P-Y-H-R-D"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-R-F-T-K-D-H-E-W-V-I-V-E-G-D-V-A-T-V-G-I-T-A-Y-A-A-E-Q-L-G-D-V-V-F-V-E-T-P-E-A-G-K-V-V-K-Q-G-E-G-L-A-V-V-E-S-V-K-A-A-S-D-V-Y-A-P-V-S-G-E-V-I-E-G-N-G-E-L-A-G-A-P-E-T-V-N-A-L-P-E-S-G-G-W-F-A-K-I-K-L-A-N-P-A-E-L-D-A-L-M-D-R-D-A-Y-E-A-F-L-G-T-L"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-Q-D-I-H-P-D-Y-H-F-I-T-V-T-L-T-D-G-S-S-Y-K-T-R-S-T-Y-G-K-E-G-A-N-L-A-L-D-I-D-P-R-T-H-P-A-W-T-G-G-N-A-Q-L-M-D-R-G-G-R-V-S-R-F-N-A-K-F-A-G-F-T-G-K-K-A"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-I-R-K-P-R-S-P-K-P-V-R-N-K-V-P-A-L-K-G-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-V-R-L-T-T-G-I-E-A-V-C-Y-I-P-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-L-R-G-V-L-D-T-Q-G-V-K-D-R-K-Q-R-R-S-L-Y-G-A-K-R-P-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-R-R-A-E-K-R-Q-V-L-P-D-P-K-F-G-D-L-V-V-T-K-F-M-N-Y-V-M-Y-E-G-K-K-A-V-A-E-N-I-I-Y-G-A-F-D-I-L-E-A-K-R-K-D-Q-G-P-L-E-T-F-H-S-A-L-D-N-V-A-P-A-I-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-P-D-R-R-R-A-L-A-I-R-W-L-V-T-A-A-R-K-R-G-E-N-T-M-T-E-K-L-A-G-E-L-L-D-A-S-N-N-R-G-T-A-V-K-K-R-E-D-T-H-K-M-A-E-A-N-R-A-F-S-H-Y-R-W"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Its toxic effect is neutralized by coexpression with cognate antitoxin RelB4 but no other ParD or RelB antitoxin ### SEQUENCE -M-A-Q-D-V-G-H-A-A-P-D-T-A-T-I-F-V-A-Q-V-V-W-T-Q-R-A-M-A-D-V-Y-A-I-V-G-H-I-S-E-Q-S-R-P-L-A-A-Q-R-L-A-K-R-L-F-D-T-G-A-S-L-A-T-Y-P-E-R-G-R-V-S-T-Q-G-R-R-E-I-V-A-I-S-P-Y-V-L-R-Y-R-I-V-G-D-R-V-V-I-G-S-V-R-H-G-A-R-R-P-I"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Neutralizes the effect of cognate toxin ParE4, but no other RelE or ParE toxin ### SEQUENCE -M-P-S-N-G-I-V-R-S-W-R-R-A-M-A-T-M-N-V-S-L-P-D-A-M-R-E-W-V-E-G-Q-T-Q-S-G-R-Y-H-N-A-S-E-Y-V-R-D-L-I-R-R-D-Q-E-R-A-D-K-I-A-H-L-Q-R-L-I-D-E-G-L-D-S-G-V-G-E-R-S-L-H-E-I-R-A-E-A-R-R-R-A-G-V-D-H-E-L"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Its toxic effect is neutralized by coexpression with cognate antitoxin ParD4 but no other ParD or RelB antitoxin ### SEQUENCE -M-W-I-M-S-Y-R-L-S-R-K-A-E-Q-D-L-I-D-I-Y-V-A-G-V-G-L-F-G-V-A-Q-A-E-R-Y-Q-D-T-L-E-A-A-F-G-A-I-A-A-F-P-H-I-G-R-E-R-P-E-L-R-P-P-V-R-V-H-P-C-K-S-H-I-I-L-Y-V-L-D-E-R-G-A-L-I-V-R-V-R-H-A-G-E-D-W-V-G-E-A-G-G"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Its toxic effect is neutralized by coexpression with cognate antitoxin RelB3 but no other ParD or RelB antitoxin ### SEQUENCE -M-K-S-V-E-L-G-P-R-A-R-R-D-L-T-K-L-R-R-W-L-L-N-R-A-P-S-A-A-D-R-A-I-D-L-I-L-S-R-A-E-Q-L-A-Q-H-S-D-L-G-R-R-K-S-Q-N-M-R-E-L-Y-V-S-F-G-A-H-G-Y-V-L-Q-Y-R-V-Y-P-D-A-V-V-I-A-R-I-R-H-S-L-E-R-R"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Neutralizes the effect of cognate toxin RelE3, but no other RelE or ParE toxin ### SEQUENCE -M-S-G-V-I-A-P-D-R-V-D-D-K-R-R-M-E-H-S-Q-N-M-A-L-T-I-T-I-P-A-E-L-A-S-R-L-R-A-S-A-E-A-E-G-K-D-V-D-A-Y-A-I-D-A-L-H-V-M-S-D-E-D-W-G-Y-T-D-D-D-A-Y-W-R-E-L-R-A-H-S-D-E-V-R-R-D-G-G-I-P-L-E-D-V-K-R-W-V-A-S-W-D-T-E-N-E-L-P-P-P-E-P-R-I-K-A-R-G"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-E-K-V-P-M-T-V-A-G-Y-Q-T-L-D-E-E-L-K-R-L-K-T-V-E-R-P-A-V-I-A-A-I-A-E-A-R-S-H-G-D-L-S-E-N-A-E-Y-H-A-A-K-E-R-Q-G-W-I-E-G-Q-I-A-E-I-E-D-K-I-A-R-A-Q-V-I-D-V-T-K-L-S-G-K-Q-V-K-F-G-A-T-V-S-V-V-D-E-D-T-E-E-E-A-R-Y-Q-I-V-G-D-H-E-A-D-V-K-S-G-R-I-S-L-S-S-P-L-S-R-A-M-I-G-K-E-V-G-E-V-V-E-V-N-T-P-G-G-V-K-A-Y-E-I-L-K-V-E-W-L"} +{"text": "### FUNCTION Involved in pyrimidine catabolism Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions ### SEQUENCE -M-P-K-T-V-I-T-P-P-G-T-Q-T-P-I-A-P-F-S-P-G-T-L-A-D-G-I-V-Y-V-S-G-T-L-A-F-D-K-D-N-N-V-A-F-P-G-D-A-E-A-Q-T-R-Q-V-L-E-T-I-K-S-V-I-E-T-A-G-G-T-M-E-D-V-T-M-N-H-I-F-L-T-D-W-V-H-Y-A-P-M-N-K-V-Y-A-E-Y-F-P-G-D-K-P-A-R-Y-C-I-Q-C-G-L-V-K-P-G-F-V-V-E-I-A-S-V-A-H-I-G-K-T"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Its toxic effect is neutralized by coexpression with cognate antitoxin ParD3 but no other ParD or RelB antitoxin ### SEQUENCE -M-G-R-V-I-R-T-R-P-V-S-G-D-L-D-R-V-F-R-D-V-C-E-N-N-G-V-K-V-A-S-A-Q-L-N-R-I-E-S-V-F-H-R-L-S-A-F-P-R-L-G-R-D-R-S-D-L-R-P-G-L-R-T-F-S-V-K-P-W-Q-V-L-Y-R-L-N-G-E-D-V-V-I-L-R-I-L-D-G-R-M-N-L-A-A-Q-L-G-K-K-T"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 5-hydroxyisourate ### SEQUENCE -M-S-G-L-T-T-H-I-L-D-Q-A-S-G-K-P-A-A-G-V-G-V-R-V-S-R-R-D-G-E-Q-T-Q-W-L-A-E-L-R-T-D-A-D-G-R-A-R-L-V-A-G-E-D-L-A-V-G-G-Y-R-L-E-F-A-I-G-D-H-F-K-A-S-G-L-P-V-S-D-P-P-F-L-D-V-V-V-I-D-F-A-V-S-N-L-D-Q-H-W-H-V-P-L-L-V-S-P-Y-G-Y-S-T-Y-R-G-S"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Neutralizes the effect of cognate toxin RelE2, but no other RelE or ParE toxin ### SEQUENCE -M-A-I-C-Y-A-R-F-M-V-P-E-P-S-I-F-E-I-D-A-E-A-E-E-A-A-D-A-E-G-M-A-D-I-A-A-G-R-V-V-P-H-E-E-V-S-A-W-L-D-T-W-G-T-P-E-E-K-P-A-P-E-T-W-R-K"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Its toxic effect is neutralized by coexpression with cognate antitoxin RelB2 but no other ParD or RelB antitoxin ### SEQUENCE -M-A-Q-V-V-W-T-W-R-A-L-A-D-L-T-A-I-R-D-Y-I-G-Q-F-S-P-L-A-A-Q-R-M-A-L-R-L-K-T-A-A-D-S-L-A-E-Y-P-E-R-G-R-L-A-T-A-T-L-R-E-L-V-V-V-P-P-Y-V-I-R-Y-Y-V-A-D-G-L-V-H-I-V-R-I-R-H-A-A-R-L"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-I-C-P-P-G-E-N-K-S-M-A-E-R-K-Q-G-G-Q-G-N-G-V-G-S-S-V-V-T-E-V-K-P-K-T-Q-K-P-S-L-Y-R-V-L-I-L-N-D-D-Y-T-P-M-E-F-V-V-Y-V-L-E-R-F-F-N-K-S-R-E-D-A-T-R-I-M-L-H-V-H-Q-N-G-V-G-V-C-G-V-Y-T-Y-E-V-A-E-T-K-V-A-Q-V-I-D-S-A-R-R-H-Q-H-P-L-Q-C-T-M-E-K-D"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-V-L-D-I-E-D-F-A-D-A-L-P-Q-Y-A-A-V-V-G-L-D-P-G-E-K-T-I-G-V-A-V-S-D-V-T-R-T-V-A-S-P-L-A-L-I-E-K-T-K-F-S-K-D-A-E-Q-L-F-K-L-M-D-S-R-G-A-V-A-I-V-I-G-L-P-M-N-M-D-G-T-E-G-V-R-C-Q-S-N-R-A-L-G-R-N-L-L-R-L-K-P-D-L-P-I-T-F-W-D-E-R-L-S-T-A-A-V-T-R-V-L-I-D-E-H-D-I-S-R-K-R-R-D-E-V-V-D-K-M-A-A-G-W-I-L-Q-G-A-L-E-R-L-R-G-L"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-A-I-D-A-A-T-V-R-K-V-A-R-L-A-R-I-A-T-P-E-E-R-L-E-P-L-A-Q-E-L-N-G-I-M-T-W-I-E-Q-L-A-E-V-D-T-D-G-C-E-P-L-T-S-V-V-A-A-G-L-P-L-R-E-D-V-V-T-M-G-G-D-P-A-R-V-T-S-N-A-P-K-S-I-N-N-F-F-V-V-P-K-V-V-E"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-L-L-E-F-P-G-T-V-S-E-L-L-P-N-A-T-F-R-V-K-L-E-N-D-H-E-I-I-A-H-T-A-G-K-M-R-K-N-R-I-R-V-L-A-G-D-K-V-L-V-E-M-T-P-Y-D-L-T-K-G-R-I-T-Y-R-F-K"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-S-A-K-C-P-I-C-A-K-P-V-D-S-A-F-R-P-F-C-S-K-R-C-A-D-V-D-L-Q-R-W-L-S-G-R-Y-V-V-A-G-G-D-D-D-E-E-N-P-P-S-Q-D-I-N-R-E"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-T-D-A-A-N-P-P-A-D-I-S-A-L-S-F-E-E-A-L-S-Q-L-E-R-I-V-Q-E-L-E-S-G-Q-A-A-L-E-R-S-I-D-I-Y-E-R-G-A-A-L-K-A-H-C-E-K-K-L-E-A-A-R-L-K-V-E-K-I-V-L-G-Q-G-G-A-V-A-A-E-P-A-E-F-N"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-M-S-W-I-H-W-V-I-V-L-G-I-V-A-L-L-F-G-G-R-G-K-L-S-S-I-M-G-D-A-A-K-G-I-K-A-F-K-D-G-L-K-D-E-S-S-S-E-V-A-D-N-K-A-K-S-A-L-P-R-T-E-A-E-A-E-E-L-R-K-S"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-L-P-D-I-G-G-T-E-L-L-I-I-A-A-V-A-L-I-V-V-G-P-K-D-L-P-A-L-L-R-K-V-G-Q-F-V-G-R-M-R-G-M-A-S-E-F-R-A-S-F-D-E-M-A-R-Q-S-E-L-D-E-L-R-R-E-V-Q-A-M-R-S-G-Q-F-T-N-P-V-Q-D-A-A-D-A-A-R-D-V-Q-V-D-Q-V-F-A-D-I-D-A-S-L-S-S-G-A-M-Q-A-H-P-Y-A-A-G-E-T-H-N-S-I-L-P-T-A-E-P-S-A-E-I-V-E-A-K-P-K-R-A-P-R-K-K-A-V-A-E-P-V-A-A-E-P-V-L-V-E-P-V-K-A-P-R-K-R-A-S-Q-K-Q-E-I-T-V-E-A-P-K-A-V-R-A-P-R-K-R-A-S-K-A-G-D-S-T-A-S-D-I-V-S"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-K-L-L-L-V-A-A-G-G-A-V-G-S-V-A-R-Y-L-V-G-V-G-A-M-R-V-M-G-P-G-W-P-Y-G-T-F-T-V-N-V-V-G-G-F-L-M-G-C-L-A-S-W-L-A-H-R-G-N-T-S-S-E-T-W-R-V-M-L-G-V-G-V-L-G-G-F-T-T-F-S-S-F-S-L-E-T-A-L-M-I-Q-K-R-A-Y-G-Q-A-F-T-Y-S-A-A-S-V-L-L-A-I-A-A-L-F-A-G-L-L-V-A-R-K-V-F-A"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur , and thus conserves the redox energy in a proton gradient ### SEQUENCE -M-S-E-A-L-E-L-L-G-Q-D-I-V-A-R-A-P-G-V-L-G-H-S-V-A-F-G-E-L-T-I-V-A-R-A-A-S-V-I-D-T-L-T-F-L-R-D-D-A-A-C-R-F-H-Q-L-I-D-L-T-G-V-D-Y-P-E-R-A-A-R-F-D-V-V-Y-H-L-L-S-L-V-K-N-H-R-I-R-L-K-V-S-T-D-E-D-T-P-V-P-S-V-T-P-V-F-P-V-A-D-W-F-E-R-E-A-F-D-M-Y-G-I-F-F-D-G-H-P-D-L-R-R-I-L-T-D-Y-G-F-H-G-H-P-L-R-K-D-F-P-M-T-G-Y-V-E-V-R-Y-D-D-E-L-K-R-V-V-Y-E-P-V-K-I-T-E-F-R-A-F-D-F-L-S-P-W-E-G-A-K-Y-A-L-P-G-D-E-K-A-Q"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-A-A-E-K-P-V-L-S-R-Y-R-D-R-M-D-K-A-V-S-A-L-K-E-E-F-G-S-L-R-T-G-R-A-S-A-S-L-L-D-Q-V-M-V-E-A-Y-G-S-T-T-P-L-N-A-V-A-S-V-S-V-P-E-P-R-Q-I-N-V-S-V-W-D-R-G-V-V-V-S-V-E-K-A-I-R-A-S-G-L-G-L-N-P-V-V-E-G-Q-N-L-R-I-P-I-P-P-L-T-E-E-R-R-R-D-L-Q-K-I-A-G-K-Y-A-E-Q-Q-K-I-A-V-R-N-V-R-R-D-A-N-D-D-L-K-K-A-E-K-D-G-A-I-A-E-D-E-R-K-K-M-E-T-E-V-Q-K-M-T-D-D-A-I-K-R-I-D-E-A-L-K-T-K-E-H-E-I-M-Q-V"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-S-A-E-K-K-Q-N-L-Q-D-T-F-L-N-S-V-R-K-S-K-T-P-L-T-I-F-L-V-N-G-V-K-L-Q-G-V-V-S-W-F-D-N-F-C-V-L-L-R-R-D-G-Q-S-Q-L-V-Y-K-H-A-I-S-T-I-M-P-A-Q-P-V-Q-L-Y-E-P-S-A-D-A-D-D"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-D-I-L-E-R-V-R-K-I-V-I-E-H-L-D-A-D-P-E-K-V-T-E-K-A-S-F-I-D-D-L-G-A-D-S-L-D-N-V-E-L-V-M-A-F-E-E-E-F-D-I-E-I-P-D-D-A-A-E-H-I-Q-T-V-G-D-A-V-K-F-I-T-E-K-T-A"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-F-Y-E-H-V-V-I-A-R-Q-D-I-S-P-Q-Q-A-E-A-L-N-E-Q-L-K-A-L-I-E-E-N-G-G-H-I-A-K-I-E-Y-W-G-L-R-N-L-T-Y-R-I-K-K-N-R-K-G-H-Y-S-L-L-A-I-D-A-P-A-P-A-V-K-E-M-E-R-Q-L-L-I-N-E-D-V-L-R-F-M-T-I-R-V-E-E-L-D-L-E-L-S-P-V-L-A-R-R-D-R-G-D-R-P-E-R-P-R-E-D-F-G-A-Q-A-Q-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-T-D-T-T-A-P-E-A-G-A-P-A-A-A-A-G-G-A-R-R-P-F-F-R-R-R-K-V-C-P-F-S-G-A-N-A-P-K-I-D-Y-K-D-V-K-L-L-Q-R-Y-V-S-E-R-G-K-I-V-P-S-R-I-T-A-V-S-A-K-K-Q-R-E-L-A-K-A-I-K-R-A-R-F-L-A-L-L-P-Y-V-V-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-L-E-R-V-E-G-T-G-V-L-G-D-E-V-T-V-K-D-G-F-A-R-N-Y-L-L-P-R-G-K-A-L-R-A-T-K-A-N-L-A-T-F-E-A-Q-R-A-E-I-E-A-R-N-V-K-N-R-E-S-A-A-K-N-G-E-A-L-D-G-T-Q-Y-I-L-I-R-Q-A-G-E-S-G-Q-L-Y-G-S-V-A-G-R-D-V-A-D-A-I-K-A-E-G-G-K-V-D-R-S-M-V-V-L-D-K-P-I-K-T-L-G-V-H-E-V-K-V-K-L-H-A-E-V-T-I-T-V-T-L-N-I-A-R-S-Q-D-E-A-E-R-Q-A-R-G-E-N-V-I-N-S-Q-F-E-E-D-R-A-A-E-A-E-A-A-Q-D-M-A-E-G-G-A-G-S-F-E-G-D-H-Y-E-A"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-L-S-H-L-R-P-A-L-V-S-M-G-L-F-T-V-L-L-G-L-A-Y-P-L-A-V-T-G-V-A-Q-A-A-F-P-N-Q-A-N-G-S-L-I-R-D-A-D-G-K-V-V-G-S-A-L-I-G-Q-V-F-A-K-P-E-Y-F-H-G-R-P-S-A-A-G-A-G-Y-D-A-S-A-S-S-G-S-N-M-G-P-L-N-E-T-L-I-A-R-L-K-T-D-A-A-A-L-R-A-E-N-P-G-V-A-I-P-A-D-A-V-T-T-S-G-S-G-L-D-P-D-I-S-P-A-N-A-R-F-Q-A-P-R-V-A-G-A-R-G-V-P-E-K-D-V-T-A-L-I-D-A-Q-V-Q-Q-P-L-L-G-F-I-G-Q-P-R-V-N-V-L-A-L-N-R-A-L-D-A-R-Y-P-P-L-A-S-Q-K-D-G"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-I-G-I-G-S-D-L-C-D-I-R-R-I-E-K-S-L-E-R-F-G-D-R-F-T-H-K-V-F-T-E-T-E-R-T-R-S-E-R-K-P-D-R-A-S-S-Y-A-K-R-F-A-A-K-E-A-C-S-K-A-L-G-T-G-L-K-R-G-V-H-L-A-G-M-G-V-V-N-L-P-S-G-Q-P-T-M-A-L-T-G-G-A-L-E-R-L-K-A-M-V-P-E-G-M-E-P-V-I-H-L-S-L-T-D-D-H-P-Y-A-Q-A-F-V-I-I-E-A-L-P-K-R"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-V-N-K-V-I-L-V-G-N-L-G-A-D-P-E-I-R-S-L-G-S-G-D-R-V-A-N-L-R-I-A-T-S-E-T-W-R-D-R-S-S-G-E-R-K-E-K-T-E-W-H-R-V-V-I-F-N-D-N-L-V-K-V-A-E-Q-Y-L-R-K-G-S-T-V-Y-I-E-G-A-L-Q-T-R-K-W-T-D-N-T-G-Q-E-K-Y-S-T-E-I-V-L-Q-K-F-R-G-E-L-T-M-L-G-G-R-G-G-D-A-G-M-S-S-G-G-G-D-E-Y-G-G-G-Y-S-G-G-G-S-S-F-G-G-G-Q-R-S-Q-P-S-G-P-R-E-S-F-S-A-D-L-D-D-E-I-P-F"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-K-G-A-T-L-T-R-A-D-L-C-E-A-V-H-E-E-V-G-L-T-R-Q-D-C-A-G-L-V-E-R-T-L-D-L-V-A-E-A-L-E-Q-G-E-T-V-K-L-S-G-F-G-V-F-Q-V-R-A-K-R-A-R-M-G-R-N-P-K-T-G-E-P-A-E-I-E-P-R-R-V-I-G-F-R-A-S-Q-V-M-K-A-R-I-D-R-A-L-G-G"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-G-N-R-I-Q-P-R-S-V-A-R-L-A-A-V-Q-A-L-Y-Q-M-E-V-S-G-A-G-V-D-S-V-I-R-E-F-G-E-H-R-F-D-R-D-V-E-G-E-Q-L-A-A-A-D-E-T-F-F-A-D-L-A-R-G-V-V-T-N-Q-A-K-I-D-Q-G-I-V-K-R-L-A-S-G-W-R-L-E-R-L-D-A-T-A-R-A-V-L-R-A-G-A-F-E-L-M-Y-R-S-D-V-P-T-E-V-V-I-N-E-Y-V-E-I-A-K-S-F-F-E-G-P-E-S-G-F-I-N-G-A-L-D-A-I-A-R-D-A-R-D"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-V-E-D-K-I-R-L-L-I-V-E-G-R-S-H-S-G-I-S-D-E-L-L-R-G-A-T-Q-A-I-E-A-R-G-A-D-Y-D-V-I-T-V-S-N-A-L-Q-I-P-T-V-I-A-M-A-E-D-A-G-H-R-P-V-G-V-R-Y-D-G-Y-V-A-L-G-V-V-I-R-G-E-T-Y-H-F-E-L-V-A-N-E-T-A-R-G-L-Q-D-L-G-V-A-K-R-L-P-I-G-F-G-V-L-A-V-D-E-E-A-Q-A-L-S-R-A-R-V-S-E-G-D-R-G-G-A-A-A-K-A-C-L-E-T-I-G-L-K-R-Q-L-L-G-Q-A-R"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-F-C-G-H-A-E-S-Q-V-K-D-S-R-P-S-E-D-G-A-A-I-R-R-R-R-M-C-P-E-C-G-G-R-F-T-T-F-E-R-V-Q-L-R-E-L-I-I-V-K-R-S-G-R-R-S-P-F-D-R-D-K-L-V-R-S-V-G-L-A-T-Q-K-R-P-V-D-P-E-R-V-E-R-M-V-N-G-I-V-R-Q-L-E-S-M-G-E-T-E-L-P-S-S-T-V-G-E-M-V-M-K-A-L-K-S-L-D-D-V-A-Y-V-R-Y-A-S-V-Y-R-D-F-K-E-T-S-D-F-A-K-F-L-T-E-E-G-L-S-D-G-G-E-E-E-L"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-E-P-A-R-V-K-R-R-E-R-K-N-I-T-S-G-V-A-H-V-N-A-S-F-N-N-T-M-I-T-I-T-D-A-Q-G-N-T-I-S-W-S-S-A-G-M-M-G-F-K-G-S-R-K-S-T-P-Y-A-A-Q-M-A-A-E-D-A-G-K-K-A-A-E-H-G-V-K-T-L-E-V-N-V-S-G-P-G-S-G-R-E-S-A-L-R-A-L-Q-A-A-G-M-T-I-T-T-I-R-D-V-T-P-I-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-T-N-K-R-V-L-I-A-L-Q-Y-I-H-G-I-G-Q-K-S-A-R-E-I-I-T-K-V-G-I-E-D-A-R-R-V-N-Q-L-T-D-A-E-V-L-Q-I-R-E-T-I-D-R-D-Y-T-V-E-G-D-L-R-R-E-N-S-M-N-I-K-R-L-M-D-L-A-C-Y-R-G-L-R-H-R-K-G-L-P-V-R-G-Q-R-T-H-T-N-A-R-T-R-K-G-P-A-K-P-I-A-G-K-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-K-L-N-E-L-A-P-R-E-G-S-T-K-G-R-M-R-V-G-R-G-P-G-S-G-K-G-K-T-A-G-R-G-V-K-G-Q-K-A-R-S-G-V-A-I-N-G-F-E-G-G-Q-M-P-L-H-M-R-M-P-K-R-G-F-N-N-P-F-R-L-E-F-A-E-V-N-L-W-R-L-E-Q-A-V-E-A-G-K-I-K-K-G-A-E-L-D-A-A-A-L-I-A-A-G-V-I-R-R-E-L-D-G-V-K-L-L-A-K-G-E-I-K-T-A-L-K-L-T-V-Y-S-A-T-E-A-A-I-K-A-V-E-A-A-G-G-S-V-T-V-T-K-K-A-K-A-Q-A-E-A"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-L-S-P-R-E-S-A-A-K-R-A-Q-R-V-R-T-R-L-K-S-L-A-N-G-R-P-R-L-S-V-F-R-S-S-K-N-I-Y-A-Q-V-I-D-D-E-R-G-V-T-L-A-S-A-S-T-L-E-A-E-G-K-G-A-D-K-D-A-A-A-A-V-G-K-L-V-A-E-R-A-I-E-K-G-V-K-D-V-V-F-D-R-G-S-Y-I-F-H-G-R-V-K-A-L-A-D-A-A-R-E-A-G-L-N-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-A-V-A-I-P-S-G-V-Q-V-T-L-A-G-Q-T-V-T-V-K-G-P-K-G-Q-L-S-W-T-I-A-D-E-V-E-V-K-Q-E-G-A-E-L-L-L-A-P-R-V-D-T-K-R-A-K-G-M-W-G-L-S-R-T-L-V-A-N-M-V-H-G-V-T-V-G-F-E-E-S-L-E-L-V-G-V-G-Y-R-A-A-M-K-G-T-A-L-S-L-Q-L-G-F-S-H-D-V-D-V-A-A-P-A-G-V-T-F-A-V-P-K-Q-T-E-I-K-I-A-G-I-D-K-Q-A-V-G-E-I-A-A-K-I-R-R-I-R-P-P-E-P-Y-K-G-K-G-V-R-Y-A-G-E-K-V-R-R-K-E-G-K-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-N-D-P-L-S-D-M-I-A-R-I-K-N-A-A-Q-R-K-R-S-K-V-S-T-P-A-S-K-L-R-A-R-V-L-D-V-L-A-D-E-G-Y-I-R-G-Y-S-L-V-E-K-P-G-A-F-P-E-F-E-I-E-L-K-Y-F-D-G-E-P-V-I-A-E-I-S-R-V-S-K-P-G-R-R-V-Y-S-S-I-K-D-L-K-P-I-K-N-G-L-G-I-S-I-L-S-T-P-K-G-V-M-S-D-T-A-A-R-D-A-N-V-G-G-E-V-L-C-R-V-Y"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-A-V-N-R-N-E-A-V-K-A-L-V-K-K-F-A-E-K-R-A-A-L-K-A-I-A-N-D-E-T-L-P-L-E-E-R-F-E-A-R-L-K-L-A-K-L-P-R-N-S-A-A-I-R-I-R-N-R-C-E-V-T-G-R-P-R-A-Y-Y-R-K-L-K-M-S-R-V-A-L-R-E-L-G-S-Q-G-Q-I-P-G-L-V-K-S-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-D-Q-A-Y-E-P-R-L-K-T-V-Y-R-E-R-I-R-A-A-M-K-E-Q-F-G-Y-T-N-E-M-Q-I-P-K-L-D-K-I-V-L-N-M-G-I-G-E-A-V-A-D-S-K-K-A-Q-T-A-L-K-D-L-Q-A-I-A-G-Q-K-P-V-A-T-K-A-R-K-S-I-A-G-F-K-L-R-E-G-M-V-V-G-A-K-V-T-L-R-K-D-R-M-Y-E-F-L-D-R-L-V-T-I-A-L-P-R-V-K-D-F-R-G-L-N-G-K-S-F-D-G-R-G-N-Y-A-M-G-L-K-E-H-L-V-F-P-E-I-N-Y-D-Q-I-E-Q-I-W-G-M-D-I-I-V-C-T-T-A-K-S-D-Q-E-A-K-A-L-L-K-E-F-Q-F-P-F-V-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-K-K-G-D-R-V-V-V-L-A-G-K-D-K-G-K-Q-G-S-V-L-Q-V-L-P-K-D-N-R-V-V-V-E-G-V-N-M-V-S-R-H-T-K-P-T-Q-A-D-P-Q-G-G-I-K-N-K-E-A-A-L-H-V-S-N-V-A-V-V-D-S-N-G-K-P-T-R-V-G-F-K-I-E-G-D-K-K-V-R-V-A-K-T-T-G-E-V-I-N-G"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-N-L-E-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-A-G-R-R-Y-A-S-V-G-D-V-I-V-V-S-V-K-E-A-I-P-R-G-R-V-K-K-G-D-V-L-R-A-V-V-V-R-V-N-Q-N-L-K-R-K-D-G-S-V-I-R-F-D-K-N-A-A-V-I-V-N-K-Q-S-E-P-V-G-T-R-I-F-G-P-V-P-R-E-L-R-A-K-N-H-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-I-L-E-G-V-V-V-S-D-K-G-D-K-T-V-V-V-K-V-E-R-T-I-V-H-P-V-L-K-K-I-V-R-Q-S-K-K-Y-H-A-H-D-E-A-N-A-Y-K-A-G-E-A-I-R-I-I-E-C-A-P-K-S-K-L-K-T-W-E-V-L-P-K-A-S-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-S-P-K-K-T-K-F-R-K-Q-F-K-G-R-I-H-G-T-S-K-G-G-T-L-L-N-F-G-S-Y-G-L-K-A-V-E-P-E-R-I-T-A-R-Q-I-E-A-A-R-R-A-I-T-R-Q-M-K-R-Q-G-R-V-W-I-R-I-F-P-D-V-P-V-T-G-K-P-A-E-V-R-M-G-K-G-K-G-A-V-D-Y-W-A-A-R-V-A-P-G-R-I-M-F-E-I-D-G-V-P-D-D-I-A-R-E-A-L-R-L-G-A-A-K-L-P-I-R-T-R-V-V-T-R-I-D-A-G-V-A-Q-E-A"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-K-Q-K-Q-E-R-R-L-P-A-A-E-A-M-C-K-V-R-T-L-R-T-S-P-R-K-L-N-L-V-A-Q-S-I-R-G-L-N-V-Q-R-A-L-N-E-L-E-F-S-H-K-R-I-A-Q-D-V-R-K-A-L-Y-S-A-I-S-N-A-E-N-N-H-N-L-D-I-D-S-L-V-V-A-E-A-Y-V-G-K-N-L-I-M-K-R-F-S-P-R-A-R-G-R-A-T-R-V-E-K-P-F-S-E-I-T-I-V-V-R-E-L-G-E-A-A"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-V-W-K-G-P-F-V-D-G-Y-L-L-K-K-A-D-A-A-L-S-S-G-R-K-D-V-I-K-T-W-S-R-R-S-T-I-M-P-Q-F-V-G-L-T-F-G-V-H-N-G-H-K-H-V-P-V-L-V-S-E-D-M-V-G-M-K-F-G-E-F-A-P-T-R-N-F-P-G-H-A-A-D-K-K-A-K-R-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-A-A-T-A-R-H-Y-D-T-I-L-S-P-V-I-T-E-K-T-T-L-L-S-E-Q-N-K-V-V-F-K-V-A-N-D-A-T-K-D-E-I-A-A-A-V-E-E-L-F-K-V-K-V-T-K-V-N-T-I-V-T-K-G-K-T-K-R-F-R-G-I-V-G-R-R-N-D-V-K-K-A-I-V-T-L-A-E-G-Q-S-I-D-I-T-T-G-L"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-D-R-Q-N-I-R-I-R-L-K-A-F-D-H-R-V-L-D-H-S-T-R-E-I-V-N-T-A-K-R-T-G-A-T-V-R-G-P-I-P-L-P-T-L-I-E-K-F-T-V-N-R-S-P-H-V-D-K-K-S-R-E-Q-F-E-I-R-T-H-K-R-V-L-D-I-V-D-P-T-P-Q-T-V-D-A-L-M-K-L-D-L-S-A-G-V-D-V-E-I-K-L"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-K-P-I-A-E-N-R-R-A-R-F-D-Y-F-I-E-E-T-F-E-A-G-I-M-L-T-G-T-E-V-K-S-L-R-T-G-R-A-N-I-A-E-S-Y-A-S-V-E-G-R-E-I-V-L-I-N-A-D-I-P-P-Y-G-H-A-N-R-F-N-H-E-P-R-R-H-R-K-L-L-L-H-R-R-Q-I-D-K-L-I-G-A-V-Q-R-E-G-R-T-L-V-P-I-K-L-Y-W-N-D-K-G-L-A-K-L-E-V-G-L-A-K-G-K-K-L-H-D-K-R-D-T-A-A-E-R-D-W-Q-R-D-K-A-R-L-M-K-G-D-R-G-D"} +{"text": "### FUNCTION Antitoxin component of a non-functional type II toxin-antitoxin Does not neutralize the effect of any of the RelE or ParE toxins ### SEQUENCE -M-F-W-I-F-V-M-A-K-P-A-S-L-S-I-E-L-D-S-D-L-D-R-R-L-S-E-I-A-E-G-M-D-Q-P-K-T-A-I-I-E-R-A-L-R-D-F-V-E-L-R-D-W-Q-D-A-A-I-D-E-G-L-R-A-A-E-E-G-R-V-F-D-H-D-K-V-G-E-W-I-D-S-W-G-T-P-N-E-R-P-M-P-S-R-D"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-Q-T-P-P-V-K-D-G-P-R-I-N-D-E-I-R-V-P-R-V-L-L-I-D-Q-H-G-E-K-Q-G-E-M-P-T-A-S-A-M-E-A-A-E-E-A-G-L-D-L-V-E-I-V-P-N-A-N-P-P-V-C-K-I-L-D-Y-G-K-F-K-F-Q-E-Q-K-K-K-N-E-A-R-K-R-Q-K-V-V-E-L-K-E-I-K-L-R-P-N-I-D-S-H-D-Y-D-V-K-A-K-A-M-H-R-F-F-E-E-G-D-K-V-K-V-T-L-R-F-R-G-R-E-M-A-H-P-E-L-G-M-K-L-L-Q-K-V-K-A-D-F-D-E-V-A-K-V-E-Y-E-P-R-M-E-G-R-Q-M-I-M-I-L-A-P-R"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-V-A-H-A-K-H-K-K-V-L-E-Q-A-K-G-F-Y-G-R-R-K-N-T-I-R-T-A-K-A-A-V-D-K-A-G-Q-Y-A-Y-R-D-R-K-V-R-K-R-A-F-R-S-L-W-I-Q-R-I-N-A-G-A-R-L-E-G-F-T-Y-S-Q-F-I-H-G-L-D-V-A-G-I-V-M-D-R-K-V-L-A-D-I-A-G-N-D-P-A-A-F-K-A-I-A-D-K-V-R-A-A-L-A"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-R-R-L-I-V-L-F-A-A-A-L-A-V-L-G-A-T-A-P-A-L-A-A-P-K-T-E-T-A-V-F-A-G-G-C-F-W-C-M-E-H-D-M-Q-G-V-P-G-V-L-K-V-E-S-G-Y-T-G-G-H-L-K-N-P-T-Y-R-D-V-T-S-E-T-S-G-H-Y-E-A-V-R-V-T-Y-D-P-A-K-L-D-Y-G-F-L-L-Y-R-Y-W-R-L-V-D-P-T-D-D-G-G-Q-F-C-D-R-G-P-S-Y-R-P-A-V-F-V-T-P-A-Q-R-P-I-A-E-K-S-R-T-E-A-A-K-R-L-K-T-G-T-M-K-T-Q-I-L-P-A-Q-T-F-Y-L-A-E-E-Y-H-R-D-Y-A-K-R-N-K-L-N-Y-F-A-Y-R-T-G-C-G-R-D-A-R-L-K-Q-V-W-G-G"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-D-P-V-P-P-R-I-A-I-V-V-S-Q-F-N-P-E-V-T-D-G-L-L-K-G-A-L-D-H-L-A-A-Q-G-A-P-V-A-A-P-D-I-I-A-A-P-G-A-Y-E-L-P-L-I-A-Q-T-L-A-R-T-G-R-Y-A-G-V-V-C-L-G-C-V-I-K-G-E-T-A-H-F-E-F-I-S-L-G-A-S-L-G-L-M-A-A-G-L-Q-T-E-T-P-V-S-F-G-V-L-T-T-Y-T-D-E-Q-A-V-A-R-S-R-D-D-A-E-N-K-G-R-E-A-A-N-A-C-L-S-T-V-Q-T-L-R-R-I-R-E-N-A-L-A"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Neutralizes the effect of cognate toxin RelE1, but no other RelE or ParE toxin ### SEQUENCE -M-A-D-G-F-D-I-H-I-D-Q-E-Q-A-A-R-L-K-V-V-A-D-R-L-G-M-S-V-S-E-Y-A-V-A-L-I-D-A-G-L-T-G-A-A-P-K-A-I-D-P-D-P-A-I-D-E-A-I-A-D-A-I-E-R-G-D-E-P-A-I-S-R-D-E-F-R-A-H-I-R-R-V-T-A-G-L-G"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Its toxic effect is neutralized by coexpression with cognate antitoxin RelB1 but no other ParD or RelB antitoxin ### SEQUENCE -M-T-F-T-V-L-V-S-V-R-A-K-R-D-F-N-R-L-I-V-W-L-V-E-R-D-P-R-A-A-A-R-L-G-P-L-L-E-A-A-L-D-S-L-T-E-A-P-S-R-G-R-S-V-G-P-T-T-R-E-I-S-I-P-F-G-Q-S-A-Y-V-I-R-Y-R-L-L-G-S-S-V-H-V-T-R-I-W-H-G-L-E-Q-R"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-A-E-A-P-H-T-L-K-F-E-R-L-R-K-R-P-D-F-L-L-A-A-K-A-P-A-L-S-R-G-A-V-F-I-Q-M-R-Q-R-T-D-D-D-P-T-V-R-V-G-F-T-A-T-K-K-I-G-G-A-V-E-R-N-R-A-K-R-R-L-R-E-A-A-R-L-V-L-P-L-H-A-R-P-S-H-D-Y-V-F-I-A-R-G-G-T-G-T-R-E-W-A-R-L-L-D-D-V-K-T-A-L-I-S-L-A-A-D-L-D-R-G-G-T-K-V-S-R-R-S-N-G-A-L-H-D-A-A-P-S-S-Q-P-D-P-T-V-S-G"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-V-A-A-S-S-L-R-K-G-S-V-V-D-M-D-G-K-L-Y-V-V-L-S-A-E-N-I-H-P-G-K-G-T-P-V-T-Q-L-N-M-R-R-I-S-D-G-V-K-V-S-E-R-Y-R-T-T-E-Q-V-E-R-A-F-V-D-D-R-N-H-T-F-L-Y-S-D-G-D-G-Y-H-F-M-N-P-E-S-Y-D-Q-L-V-A-T-E-D-V-I-G-D-A-A-P-Y-L-Q-E-G-M-T-V-I-L-S-T-H-N-D-V-P-I-A-I-D-L-P-R-T-V-V-L-E-I-V-D-T-E-P-S-V-K-G-Q-T-A-S-S-S-Y-K-P-A-V-L-S-N-G-V-K-T-T-V-P-P-Y-I-T-A-G-T-K-V-V-I-L-T-E-D-G-S-Y-V-E-R-A-K-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-L-G-Y-I-K-L-Q-V-K-A-G-S-A-T-P-S-P-P-I-G-P-A-L-G-Q-R-G-V-N-I-M-G-F-C-K-E-F-N-A-R-T-E-N-V-E-K-G-T-P-L-P-T-V-I-T-V-Y-Q-D-K-S-F-T-F-I-T-K-T-P-P-A-T-H-Y-L-K-Q-I-T-G-L-K-S-G-A-K-L-T-G-R-E-T-V-G-E-V-T-R-T-Q-L-R-E-I-A-E-K-K-M-K-D-L-N-A-N-D-L-E-A-A-A-K-I-I-E-G-S-A-K-A-M-G-L-K-I-V-E-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-K-L-E-K-L-V-E-E-L-S-T-L-S-V-L-E-A-A-E-L-S-K-L-L-E-E-K-W-G-V-S-A-A-A-P-V-A-V-A-A-A-G-G-A-A-A-A-P-A-E-A-A-E-E-Q-T-E-F-T-V-V-L-V-D-G-G-D-K-K-I-N-V-I-K-E-V-R-G-V-R-P-D-L-G-L-K-E-A-K-D-L-V-E-G-A-P-Q-N-V-V-E-N-V-S-K-Q-Q-A-E-E-I-S-K-K-L-T-E-A-G-A-K-I-Q-I-K"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-A-E-I-I-L-N-V-E-V-R-D-G-A-G-T-G-N-A-R-A-T-R-R-A-G-K-V-P-G-V-L-Y-G-G-G-K-A-P-V-N-I-A-V-K-A-N-E-F-R-K-S-L-Y-T-G-K-L-L-G-H-L-V-T-L-Q-Y-G-E-E-K-Q-S-V-I-A-K-A-V-Q-F-H-P-V-T-D-E-P-V-H-F-D-L-Y-R-V-D-E-H-Q-L-I-K-I-E-V-P-V-H-F-K-N-H-E-T-S-V-G-L-K-K-G-G-T-L-E-V-I-R-H-T-V-E-L-A-C-P-A-D-K-I-P-E-E-L-V-I-D-L-A-G-H-D-I-G-D-V-I-R-I-S-E-V-K-L-P-E-G-V-K-P-A-M-D-R-D-F-V-I-A-N-V-K-A-S-S-A-A-Q-S-D-A-G-D-T-T-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-E-H-Q-S-L-F-S-F-S-N-P-E-F-W-V-L-A-A-L-V-I-F-F-G-L-L-V-V-L-K-V-L-P-G-A-L-F-G-A-L-D-G-Y-A-A-K-I-K-A-E-L-D-E-A-Q-Q-L-R-E-E-A-Q-A-L-L-A-D-V-K-A-Q-R-E-D-A-E-R-Q-A-A-A-M-L-E-A-A-K-A-D-A-K-R-L-A-E-E-A-K-E-K-L-E-E-Q-I-K-R-R-A-E-M-A-E-R-K-I-A-Q-A-E-A-Q-A-A-A-D-V-K-A-A-A-V-D-L-A-A-Q-A-A-E-T-V-L-A-A-R-L-A-G-A-K-G-D-T-L-V-D-A-A-I-G-Q-M-G-A-K-L-Q"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-K-T-G-G-K-Q-Y-R-V-Q-A-G-D-L-L-V-V-E-K-L-E-G-E-P-G-A-A-V-A-F-G-E-V-L-M-L-G-E-G-E-A-V-T-V-G-A-P-T-V-D-G-A-V-V-S-G-T-L-L-E-T-R-K-G-E-K-V-K-I-F-K-K-I-R-R-Q-G-Y-R-R-T-R-G-H-R-Q-F-E-S-V-V-R-V-T-S-V-A-G-A-G-K-E-A-K-W-E-G-T-I-D-L-T-P-K-V-I-L-D-A-R-A-R-G-L-G-D-A-A-V-P-A-T-I-P-A-P-V-E-A-A-P-A-K-A-E-A-A-P-K-K-K-A-A-P-K-K-A-A-A-K-T-E-E-G-E-A"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-I-R-R-I-L-T-V-D-N-A-A-D-L-A-T-L-K-K-I-S-T-P-V-E-A-V-T-D-E-L-R-A-L-M-D-D-M-L-E-T-M-Y-D-A-P-G-I-G-L-A-A-V-Q-V-G-E-P-V-R-V-I-V-M-D-L-A-R-E-G-E-D-K-A-P-R-Y-F-V-N-P-E-I-L-A-S-S-E-D-L-Q-G-Y-E-E-G-C-L-S-V-P-E-Y-Y-D-E-V-E-R-P-S-K-V-T-L-R-Y-M-N-Y-Q-G-E-T-V-V-E-E-A-E-G-L-F-A-V-C-I-Q-H-E-M-D-H-L-E-G-V-L-F-I-D-H-L-S-R-L-R-R-D-R-A-M-A-K-V-K-K-A-R-R-A-A"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-A-A-S-A-G-P-E-I-E-R-L-I-A-L-L-S-K-L-P-G-L-G-P-R-S-G-R-R-A-A-L-A-L-L-K-K-R-D-T-L-L-A-P-L-A-T-A-M-A-E-A-Q-A-K-V-R-T-C-G-T-C-G-S-L-D-V-T-D-P-C-A-V-C-A-D-G-S-R-D-G-R-L-L-C-V-V-E-E-V-G-S-V-W-A-M-E-R-G-G-S-F-K-G-R-Y-H-V-L-G-G-L-L-S-A-L-D-G-I-G-P-E-A-L-R-I-G-E-L-V-G-R-V-A-D-G-S-V-A-E-V-I-L-A-L-P-A-T-V-D-G-Q-T-T-A-H-Y-I-A-D-R-L-A-K-T-N-V-P-V-T-M-L-A-R-G-V-P-V-G-G-D-L-D-W-L-D-D-G-T-I-A-Q-A-L-R-A-R-R-P-A"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-K-D-L-G-G-L-M-K-Q-A-Q-A-M-Q-Q-K-L-A-D-A-Q-A-R-L-A-E-T-T-V-D-G-T-S-G-G-G-M-V-T-V-T-L-M-G-N-G-E-L-V-R-V-L-M-D-E-S-L-V-Q-P-G-E-G-E-V-I-A-D-L-I-I-A-A-H-A-D-A-K-K-K-L-D-A-K-Q-A-Q-M-M-Q-D-A-A-G-P-M-A-G-L-M-G-G-L-P-G-M-K-F"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-I-T-V-D-I-E-I-E-D-E-A-W-T-T-A-E-A-D-A-E-A-L-V-W-R-A-A-Q-A-V-L-D-A-H-E-D-I-E-G-Q-G-I-V-I-L-L-T-D-D-D-S-V-Q-A-L-N-R-D-F-R-K-K-D-Y-A-T-N-V-L-S-F-P-S-P-P-N-P-E-G-Q-I-G-D-I-A-L-A-Y-G-V-C-A-R-E-A-A-E-Q-G-K-P-L-A-H-H-L-Q-H-L-V-A-H-G-V-L-H-L-L-G-Y-D-H-E-R-D-D-E-A-E-A-M-E-A-L-E-R-E-I-L-A-G-L-D-V-P-D-P-Y-A-S-D-E-E-G-R"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-L-D-P-V-A-E-S-L-G-Y-E-I-V-R-L-R-L-M-G-G-T-E-Q-R-R-L-Q-I-M-A-E-H-P-L-L-E-D-G-S-G-G-D-M-N-V-E-D-C-A-K-L-S-R-A-V-S-E-V-L-D-A-A-D-P-I-A-G-E-Y-T-L-E-V-S-S-P-G-I-D-R-P-L-T-R-L-K-D-F-D-D-Y-A-G-L-E-A-R-I-E-L-D-R-V-A-E-G-R-K-R-F-K-G-E-L-A-G-V-E-D-D-Q-V-G-L-N-I-E-G-E-D-D-V-T-V-Y-F-P-F-A-W-V-I-D-A-K-L-V-M-T-D-A-L-M-E-R-G-A-K-Q-R-A-A-R-L-E-S-D-N-E-D-L-S-E-S-E-E-D"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-R-Q-S-D-P-K-K-G-A-L-T-G-P-S-Q-R-Q-L-R-A-G-E-L-I-R-H-A-L-V-E-I-L-R-E-E-E-L-Q-D-E-A-L-Q-N-I-S-V-T-V-S-E-V-R-M-S-P-D-L-K-H-A-I-C-F-V-E-P-L-G-A-G-L-T-G-Q-D-T-T-D-I-I-K-G-L-N-R-V-S-K-F-L-R-G-R-L-G-R-S-I-D-M-K-F-T-P-D-L-K-F-I-H-D-E-S-F-G-T-A-A-Y-M-D-K-L-F-L-D-P-R-V-Q-Q-D-T-R-R-L-S-D-V-V-D-D-E-D-E-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-I-T-L-E-R-K-A-A-L-I-A-E-H-A-R-S-T-G-D-T-G-S-A-E-V-Q-V-A-I-L-S-E-R-I-A-N-L-T-E-H-F-K-T-H-K-K-D-N-H-S-R-R-G-L-L-K-L-V-S-Q-R-R-R-L-L-D-H-L-K-K-S-D-A-A-R-Y-Q-S-L-I-E-K-L-G-L-R-R"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-S-L-T-P-V-T-L-A-S-Q-S-S-A-R-Q-M-I-L-K-N-A-G-V-A-F-E-A-V-S-P-G-V-D-E-D-A-A-K-A-G-L-L-A-E-D-V-T-P-R-D-I-A-D-A-L-A-E-M-K-A-V-K-V-S-T-K-R-P-G-L-V-I-G-A-D-Q-T-L-D-L-K-G-R-L-I-D-K-A-G-S-L-D-E-A-R-A-R-L-L-E-L-R-G-T-T-H-K-L-H-S-A-V-V-V-A-R-D-G-R-P-I-W-R-I-V-E-S-A-K-L-S-V-R-P-F-S-D-A-W-L-D-R-Y-I-E-R-R-G-E-A-L-L-W-S-V-G-C-Y-E-L-E-S-E-G-V-Q-L-F-D-K-I-E-G-D-Y-F-T-I-L-G-L-P-L-V-G-L-L-D-F-L-R-L-H-G-A-L-T-V"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-E-Y-L-T-N-E-R-I-R-A-K-Q-V-R-V-V-G-P-D-G-K-Q-L-G-I-M-D-T-R-E-A-L-R-L-A-Q-E-M-D-L-D-L-V-L-V-G-P-N-A-D-P-P-V-A-R-I-M-D-Y-S-K-W-R-Y-E-Q-Q-M-A-E-K-E-A-R-K-K-A-K-R-T-E-V-K-S-I-K-F-R-V-K-I-D-E-H-D-Y-Q-T-K-L-G-H-I-K-R-F-L-Q-E-G-H-K-V-K-V-T-I-M-F-R-G-R-E-V-A-H-P-E-L-G-E-R-I-L-N-R-V-T-E-D-L-K-D-L-A-V-V-E-M-K-P-E-M-L-G-R-D-M-N-M-L-L-A-P-V-K-V-S-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-T-Q-T-S-E-N-V-T-W-L-T-Q-E-A-Y-N-K-L-K-E-E-L-E-Y-L-T-G-P-A-R-T-E-I-S-A-K-I-A-A-A-R-E-E-G-D-L-R-E-N-G-G-Y-H-A-A-K-E-E-Q-G-K-Q-E-L-R-V-R-Q-L-T-Q-L-L-E-S-A-K-V-G-E-A-P-A-A-D-G-V-V-A-P-G-M-V-V-T-I-A-F-D-G-D-E-D-D-T-L-T-F-L-L-A-S-R-E-Y-A-S-S-D-I-E-T-Y-S-P-Q-S-P-L-G-S-G-V-L-G-H-K-V-G-D-D-A-Q-Y-E-L-P-N-G-K-P-A-S-V-R-I-L-K-A-E-P-Y-N-G"} +{"text": "### FUNCTION Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase ### SEQUENCE -M-S-E-T-A-T-A-Y-K-L-F-R-C-L-Q-C-G-F-E-Y-D-E-A-I-G-W-P-D-D-G-I-E-P-G-T-R-W-D-E-I-P-E-D-W-S-C-P-D-C-G-A-A-K-V-D-F-E-M-V-E-V-D-R"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-E-N-R-V-V-L-R-V-K-E-E-E-E-K-S-M-G-G-I-V-L-T-S-A-S-Q-E-K-P-Q-T-A-E-V-I-A-V-G-E-G-K-T-T-N-H-G-T-L-I-S-P-L-V-K-V-G-D-T-V-I-F-E-K-F-A-G-T-T-V-K-M-D-G-E-E-F-L-I-L-K-D-S-D-L-L-A-I-V-E"} +{"text": "### FUNCTION May provide oxidative stress protection via catalytic reduction of intracellular hydrogen peroxide ### SEQUENCE -M-S-I-K-K-K-T-E-M-N-K-S-I-K-G-S-K-T-E-K-H-L-L-M-A-F-A-G-E-S-Q-A-R-S-R-Y-T-F-F-A-S-V-A-K-K-E-G-Y-E-Q-I-A-G-V-F-M-E-T-A-E-Q-E-K-E-H-A-K-R-F-F-S-F-L-E-G-G-M-L-E-I-T-A-S-F-P-A-G-I-I-G-S-T-A-E-N-L-R-A-A-A-A-G-E-N-E-E-W-T-D-L-Y-P-A-F-A-E-T-A-E-E-E-G-F-K-E-I-A-A-V-F-R-Q-I-A-K-V-E-A-E-H-E-R-R-Y-L-A-L-L-A-H-V-E-D-G-S-V-F-E-R-T-E-E-I-A-W-Q-C-R-N-C-G-Y-V-I-T-S-K-K-A-P-K-L-C-P-A-C-A-H-P-Q-A-Y-F-E-P-M-K-T-N-Y"} +{"text": "### FUNCTION Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10-methylenetetrahydrofolate ### SEQUENCE -M-M-L-I-E-C-P-N-C-G-P-R-N-E-T-E-F-S-Y-G-G-Q-A-H-V-A-Y-P-E-D-P-N-T-L-S-D-K-E-W-S-R-Y-L-F-Y-R-G-N-S-K-G-I-F-A-E-R-W-V-H-S-G-G-C-R-K-W-F-N-A-L-R-D-T-A-T-Y-E-F-K-A-V-Y-R-A-G-E-P-R-P-E-L-N-T-Q-G-G-S-R"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-T-V-D-H-T-R-M-H-A-P-A-V-R-V-A-K-T-M-Q-T-P-K-G-D-T-I-T-V-F-D-L-R-F-T-A-P-N-K-D-I-L-S-E-K-G-I-H-T-L-E-H-L-Y-A-G-F-M-R-K-H-L-N-G-A-S-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-A-P-S-E-Q-D-V-A-S-A-W-T-A-S-M-E-D-V-L-K-V-E-S-Q-N-K-I-P-E-L-N-E-Y-Q-C-G-T-A-A-M-H-S-L-D-E-A-K-Q-I-A-Q-N-I-L-A-A-G-I-S-V-N-K-N-D-E-L-A-L-P-E-A-M-L-K-E-L-K-V-D"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-L-I-Q-K-N-K-L-I-F-K-N-S-K-K-N-F-K-I-I-I-I-K-N-K-L-K-K-K-F-T-F-N-L-L-L-K-I-Q-S-I-K-K-K-K-L-K-T-K-F-I-N-R-C-Y-I-S-G-R-T-R-S-F-Y-N-R-F-S-L-N-R-N-L-I-R-K-I-G-N-F-G-Y-I-T-G-I-E-K-S-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-K-R-Y-F-K-T-V-I-L-N-D-P-K-F-G-S-Y-I-I-A-K-F-I-S-Y-I-M-N-N-G-K-K-N-L-A-Q-K-I-F-Y-Y-S-I-S-I-I-S-I-R-L-N-K-N-P-F-I-L-I-K-K-I-L-Y-N-V-Q-P-D-F-E-I-K-K-K-K-I-G-G-S-V-Y-K-I-P-I-K-I-N-L-K-R-S-L-M-F-S-M-K-W-I-V-K-N-S-K-L-R-N-E-N-G-Y-K-N-K-L-V-G-E-L-I-D-S-Y-Y-N-N-S-L-S-T-K-Q-K-D-E-L-N-K-I-I-D-Q-N-K-A-Y-S-N-F-K-I"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-T-L-N-Q-I-L-K-F-K-R-K-K-S-V-K-K-K-K-T-P-A-L-L-S-S-P-Q-K-K-G-I-C-I-K-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-K-L-S-N-K-N-E-I-T-A-Y-I-P-G-E-G-H-N-L-Q-E-H-S-N-V-L-V-R-G-G-R-V-K-D-L-P-G-V-K-Y-H-I-I-R-N-V-Y-D-L-S-G-V-I-N-R-K-T-S-R-S-K-Y-G-K-K-K"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-K-F-T-I-Y-T-G-T-T-V-P-L-M-N-D-N-I-D-T-D-Q-I-L-P-K-Q-F-L-K-L-I-D-K-K-G-F-G-K-Y-L-M-Y-A-W-R-Y-L-D-N-Q-Y-T-E-D-P-D-F-V-F-N-R-P-E-Y-R-K-A-T-I-L-I-T-G-D-N-F-G-A-G-S-S-R-E-H-A-A-W-A-L-A-D-Y-G-F-K-V-V-I-A-G-S-F-G-D-I-H-Y-N-N-E-L-N-N-G-M-L-P-I-V-Q-P-L-E-V-R-Q-A-L-A-N-L-K-P-T-D-Q-V-T-V-D-L-E-Q-Q-K-I-F-S-P-V-G-E-F-S-F-D-I-D-G-E-W-K-H-K-L-L-N-G-L-D-D-I-G-I-T-L-L-Y-E-D-L-I-A-E-Y-E-K-N-R-P-S-Y-W-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-I-F-I-N-K-G-T-K-H-F-F-Y-K-K-K-L-Y-I-F-N-V-I-K-F-S-K-F-N-K-F-Y-L-N-F-I-I-N-K-I-L-L-I-C-Y-S-K-G-K-G-F-Q-G-V-V-K-R-W-N-F-K-T-K-D-K-S-H-G-N-S-L-S-Y-R-T-L-G-S-T-G-Q-C-Q-D-P-G-R-V-F-K-K-K-K-M-P-G-R-M-G-N-K-K-F-S-L-F-V-N-I-F-F-R-K-K-N-Y-F-F-L-K-K-I-L-P-G-V-K-N-D-I-L-L-G-K-I-L"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-G-S-E-A-L-A-Y-A-L-R-L-L-A-R-K-G-Y-S-R-A-V-L-R-A-K-L-A-A-R-F-G-E-A-E-A-E-A-A-L-G-R-L-E-A-M-G-Y-L-D-D-R-A-Y-A-R-A-F-V-E-T-R-A-R-R-Y-G-P-R-K-L-R-A-L-L-L-A-R-G-V-P-E-E-V-V-E-E-V-L-P-E-A-R-V-E-E-A-L-A-V-L-R-R-Y-R-H-R-E-D-K-A-R-A-V-R-F-L-E-G-R-G-F-P-L-G-V-A-L-E-A-W-R-L-A-Q-E-E-G-E-G-Y-K"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-A-T-F-G-A-G-C-F-W-G-V-E-E-T-F-R-Q-V-P-G-V-I-D-T-A-V-G-Y-M-G-G-T-T-E-N-P-T-Y-E-E-V-C-T-D-K-T-G-H-A-E-V-V-Q-V-E-Y-D-P-E-Q-V-S-Y-E-E-L-L-N-V-F-W-D-N-H-N-P-T-T-L-N-R-Q-G-P-D-V-G-T-N-I-A-R-L-F-F-T-T-L-K-S-K-E-I-P-Q-K-N-P-K-R-K-W-I-K-A-G-V-G-K-I-R-L"} +{"text": "### FUNCTION Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-L-R-K-I-K-V-T-F-I-I-N-D-E-E-E-K-T-V-E-A-P-I-G-L-S-I-L-E-I-A-H-S-N-N-L-D-L-E-G-A-C-E-G-S-L-A-C-A-T-C-H-V-M-L-E-E-E-F-Y-N-K-L-K-K-P-T-E-A-E-E-D-M-L-D-L-A-F-G-L-T-D-T-S-R-L-G-C-Q-I-I-L-T-E-E-L-D-G-I-K-V-R-L-P-S-A-T-R-N-I-N-Y-N-G-F-K-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-T-E-Y-K-K-V-I-A-Q-N-K-K-A-I-F-N-Y-F-I-E-E-I-L-E-A-G-I-V-L-K-G-S-E-V-Q-S-L-R-Q-G-K-A-S-I-D-E-S-Y-A-S-D-N-G-H-E-V-F-L-Y-N-C-H-I-T-E-Y-E-K-A-N-R-F-N-H-S-T-R-R-P-R-K-L-L-L-H-T-K-E-I-K-K-I-I-G-K-I-R-I-K-G-Y-T-L-V-A-L-S-M-Y-F-N-K-N-N-K-V-K-V-E-L-G-I-A-K-G-K-K-L-Y-D-K-R-A-T-I-K-E-K-D-W-K-K-D-Q-S-R-L-I-R-Q-K"} +{"text": "### FUNCTION Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-S-G-K-I-K-V-T-F-I-I-N-D-G-E-E-K-T-V-E-A-P-I-G-L-S-I-L-E-I-A-H-S-N-D-L-D-L-E-G-A-C-E-G-S-L-A-C-A-T-C-H-V-I-L-E-E-E-F-Y-N-K-L-K-K-P-T-E-A-E-E-D-M-L-D-L-A-F-G-L-T-D-T-S-R-L-G-C-Q-I-I-L-T-E-E-L-D-G-I-K-V-H-L-P-A-A-T-R-N-I-K-L"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-T-E-Y-K-K-V-I-A-Q-N-K-K-A-L-F-H-Y-F-I-E-E-R-L-E-A-G-I-V-L-K-G-S-E-V-R-S-L-R-Q-G-K-A-S-I-E-E-S-H-A-A-D-T-G-H-E-V-F-L-Y-N-C-H-I-A-E-Y-E-K-A-N-R-F-N-H-A-T-R-R-P-R-K-L-L-L-H-T-K-E-I-K-K-I-I-G-R-I-R-I-K-G-Y-T-L-V-A-L-S-M-Y-F-N-K-K-N-K-V-K-V-E-L-G-I-A-K-G-K-K-L-H-D-K-R-E-S-I-K-E-K-D-W-K-R-D-Q-S-R-L-I-R-Q-K"} +{"text": "### FUNCTION Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-S-G-K-I-K-V-T-F-I-I-N-D-G-E-E-K-T-V-E-A-P-I-G-L-S-I-L-E-I-A-H-S-N-D-L-D-L-E-G-A-C-E-G-S-L-A-C-A-T-C-H-V-I-L-E-E-E-F-Y-N-K-L-K-K-P-T-E-A-E-E-D-M-L-D-L-A-F-G-L-T-D-T-S-R-L-G-C-Q-I-I-L-T-E-E-L-D-G-I-K-V-R-L-P-S-A-T-R-N-I-K-L"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-T-E-Y-K-K-V-I-A-Q-N-K-K-A-L-F-N-Y-F-I-E-E-R-L-E-A-G-I-V-L-K-G-S-E-V-Q-S-L-R-Q-G-K-A-S-I-E-E-S-H-A-A-D-T-G-H-E-V-F-L-Y-N-C-H-I-A-E-Y-E-K-A-N-R-F-N-H-A-T-R-R-P-R-K-L-L-L-H-T-K-E-I-K-K-I-I-G-R-I-R-I-K-G-Y-T-L-V-A-L-S-M-Y-F-N-K-K-N-K-V-K-V-E-L-G-I-A-K-G-K-K-L-R-D-K-R-E-S-I-K-E-K-N-W-K-R-D-Q-S-R-L-I-R-Q-K"} +{"text": "### FUNCTION Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms They allow the positioning of the organism at the favorable depth for growth This protein could be important for the shape determination of the gas vesicle ### SEQUENCE -M-S-Q-A-L-R-P-Q-A-I-K-T-S-T-T-G-S-S-L-A-D-I-L-E-R-V-L-D-K-G-I-V-I-A-G-D-I-T-V-S-V-G-S-V-E-L-L-S-I-R-I-R-L-L-V-A-S-V-D-K-A-K-E-I-G-I-N-W-W-E-S-D-P-Y-L-S-S-R-T-Q-E-L-L-A-S-N-Q-Q-L-L-E-R-V-N-L-L-E-R-E-L-A-A-T-K-A-T-G-V-I-K-K-G-V-L-G-T-P-F-F-I-W-F-Y-D-L-V"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-K-R-L-E-E-E-T-K-S-A-G-G-I-V-L-T-G-S-A-A-E-K-S-T-R-G-E-V-V-A-V-G-N-G-R-I-L-E-S-G-D-V-R-A-L-E-V-K-A-G-D-T-V-L-F-G-S-Y-V-E-K-V-E-K-I-E-G-Q-E-Y-L-I-M-R-E-D-N-I-L-G-I-V-G"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-A-V-T-Y-E-K-T-F-E-I-E-I-I-N-E-L-S-A-S-V-Y-N-R-V-L-N-Y-V-L-N-H-E-L-D-T-K-N-T-R-L-L-E-V-N-L-L-N-Q-L-E-V-A-Q-E-V-D-L-F-Q-Q-P-F-E-E-L-Q-A-I-H-E-Y-W-R-S-M-N-Q-Y-S-K-Q-I-L-N-K-E-K-V-A"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-A-V-T-Y-E-K-T-F-E-I-E-I-I-N-E-L-S-A-S-V-Y-N-R-V-L-N-Y-V-L-N-H-E-L-D-T-K-N-T-R-L-L-E-V-N-L-L-N-Q-L-E-V-A-Q-E-V-D-L-F-Q-Q-P-F-E-E-L-Q-A-I-H-E-Y-W-R-S-M-N-Q-Y-S-K-Q-I-L-T-K-E-K-V-A"} +{"text": "### FUNCTION Transcriptional repressor of the nikABCDE operon Is active in the presence of excessive concentrations of intracellular nickel ### SEQUENCE -M-Q-R-I-T-I-T-I-D-D-D-L-M-A-A-L-D-R-M-I-E-I-K-G-Y-Q-N-R-S-E-A-L-R-D-L-A-R-T-G-L-Q-Q-A-S-L-E-E-G-Q-M-E-A-C-V-G-V-L-S-Y-T-Y-D-H-S-A-R-D-L-S-K-K-L-T-N-T-H-H-D-H-H-N-I-S-V-A-S-M-H-V-H-L-D-H-D-R-C-L-E-V-S-I-L-K-G-K-T-D-D-V-R-H-F-A-D-H-V-K-A-E-R-H-V-T-H-G-T-L-A-V-L-P-L"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-Q-A-R-A-R-H-K-K-I-L-K-Q-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-T-K-A-G-Q-Y-A-Y-R-D-R-R-T-K-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-S-R-Q-N-G-L-S-Y-S-R-F-I-N-G-L-K-K-A-S-I-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-A-A-F-S-V-L-V-E-K-A-K-A-A-L"} +{"text": "### FUNCTION Part of the ecpRABCDE operon, which encodes the Ecoli common pilus ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition Positively regulates the expression of the ecp operon Also represses expression of the flagellar master operon flhDC, and consequently prevents flagellum biosynthesis and motility Acts by binding to the regulatory region of the flhDC operon ### SEQUENCE -M-T-W-Q-N-D-Y-S-R-D-Y-E-V-K-N-H-M-E-C-Q-N-R-S-D-K-Y-I-W-S-P-H-D-A-Y-F-Y-K-G-L-S-E-L-I-V-D-I-D-R-L-I-Y-L-S-L-E-K-I-R-K-D-F-V-F-I-N-L-N-T-D-S-L-T-E-F-I-N-R-D-N-E-W-L-S-A-V-K-G-K-Q-V-V-L-I-A-A-R-K-S-E-A-L-A-N-Y-W-Y-Y-N-S-N-I-R-G-V-V-Y-A-G-L-S-R-D-I-R-K-E-L-A-Y-V-I-N-G-R-F-L-R-K-D-I-K-K-D-K-I-T-D-R-E-M-E-I-I-R-M-T-A-Q-G-M-L-P-K-S-I-A-R-I-E-N-C-S-V-K-T-V-Y-T-H-R-R-N-A-E-A-K-L-Y-S-K-L-Y-K-L-V-Q"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-I-I-S-F-V-E-T-E-E-K-S-V-G-G-F-V-L-A-G-A-S-H-D-A-T-K-T-A-K-V-L-A-V-G-D-G-I-R-T-L-T-G-E-L-V-A-P-S-V-A-E-G-D-T-V-L-V-E-N-D-A-G-L-E-V-K-D-G-N-E-K-V-T-V-V-R-E-S-D-I-V-A-V-V-K"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-A-V-S-L-S-V-S-T-V-K-P-L-G-D-R-V-F-V-K-V-S-A-S-E-K-R-P-R-R-L-Y-F-P-D-T-A-K-E-K-P-Q-V-G-E-V-V-A-L-G-A-G-K-R-N-D-D-G-S-R-Q-E-L-E-V-K-V-G-D-L-L-L-Y-S-K-Y-A-G-T-D-V-K-L-G-T-E-E-Y-V-L-L-S-E-K-D-I-L-A-M-V-G"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-I-S-S-S-P-A-T-G-I-L-D-R-L-G-K-A-S-S-A-E-E-F-F-S-L-L-G-V-E-Y-D-P-K-I-V-N-V-A-R-L-H-I-L-K-R-M-G-Q-Y-L-A-Q-E-K-F-A-G-A-A-E-P-E-I-R-T-R-C-K-A-M-L-E-R-A-Y-G-D-F-V-A-S-S-P-I-D-E-R-V-F-K-V-L-K-D-A-V-S-D-S-K-K-A-A-A-F-V-P-L-S-E-L-K"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-M-A-I-C-M-G-I-I-Q-I-V-E-E-K-V-R-E-R-S-S-S-R-V-R-S-V-C-L-E-L-G-T-L-S-H-A-A-P-E-A-I-R-F-C-F-A-V-A-A-M-R-T-V-A-E-G-A-A-L-N-I-V-E-L-P-G-V-A-W-C-M-S-C-S-K-S-V-E-I-A-R-R-G-D-C-C-P-C-C-G-S-Y-Q-L-Q-V-T-A-G-E-Q-M-R-V-K-A-L-E-I-D"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-I-R-P-L-H-D-R-V-I-I-K-R-K-E-A-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-K-V-L-A-V-G-N-G-R-I-L-D-N-G-E-T-K-P-L-D-V-K-I-G-D-I-V-I-F-N-D-G-Y-G-V-K-V-E-K-I-D-N-D-E-V-L-I-M-S-E-S-D-I-L-A-I-V-E-K"} +{"text": "### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate -ureidoglycolate, generating urea and glyoxylate Involved in the utilization of allantoin as nitrogen source ### SEQUENCE -M-S-G-T-P-I-L-R-V-E-R-L-T-R-E-A-F-A-P-F-G-D-V-I-A-L-E-G-A-R-H-F-P-I-N-G-G-T-T-E-R-F-H-D-L-A-T-I-D-V-C-A-D-G-G-R-P-L-V-S-V-F-R-A-Q-P-R-A-V-P-V-A-I-T-L-M-E-R-H-P-H-G-S-Q-A-F-I-P-L-A-A-V-S-R-Y-A-I-V-V-A-P-A-G-E-F-R-P-D-A-M-R-A-F-L-A-E-G-W-Q-G-V-N-Y-A-K-G-V-W-H-H-P-L-L-A-L-D-A-V-S-D-F-V-I-V-D-R-G-G-P-Q-P-N-C-D-E-I-P-L-E-C-A-W-A-L-E-F-E-P-A-C-A-G-A-E-G-L-S"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-N-E-Q-E-P-A-P-K-R-G-R-R-F-K-E-Q-T-P-V-Q-R-A-L-G-L-L-V-R-R-E-H-S-R-K-E-L-N-R-K-L-L-A-R-G-I-E-P-D-A-A-Q-A-A-V-D-R-L-T-G-E-G-W-Q-D-D-A-R-F-A-A-A-V-V-R-N-R-A-G-S-G-Y-G-P-L-H-I-R-A-E-L-G-T-H-G-L-D-S-E-A-I-S-A-A-M-A-T-F-Q-G-D-W-T-E-N-A-R-D-L-I-H-R-R-F-G-E-Q-G-P-I-D-L-P-Q-R-R-K-A-A-D-W-L-A-R-R-G-F-D-G-N-S-I-R-A-A-T-R-F-D-L-E-D"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-R-T-I-D-E-I-I-G-T-E-N-E-V-E-S-D-T-W-T-S-R-R-L-L-L-E-K-D-G-M-G-F-S-F-H-E-T-I-I-Y-A-G-T-E-T-H-I-H-Y-Q-N-H-L-E-A-V-Y-C-V-G-G-D-G-E-I-E-T-V-S-D-G-K-V-Y-P-I-Q-D-G-T-M-Y-A-L-D-Q-H-D-E-H-Y-P-R-G-G-K-T-D-M-R-L-I-C-T-F-N-P-P-L-V-G-T-E-T-H-D-E-N-G-V-Y-P-L-L-S-K-Q-P-V-G-K"} +{"text": "### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate with acetyl coenzyme A ### SEQUENCE -M-F-W-V-I-S-K-Q-G-S-T-A-V-A-E-Q-E-E-T-L-V-F-R-V-P-T-E-D-D-G-K-A-I-W-N-L-I-N-Y-P-G-V-L-D-L-L-S-S-Y-S-Y-F-M-W-A-K-F-F-D-Q-T-S-V-V-G-E-T-N-E-Q-I-V-G-F-Y-I-G-L-H-T-T-E-Y-G-P-D-T-L-F-Y-L-A-S-C-S-D-E-T-Q-R-Q-K-G-L-A-S-R-M-L-Q-A-I-L-H-R-Y-A-W-R-N-I-R-Y-L-E-A-T-V-G-T-S-N-E-A-P-E-A-L-F-Q-K-L-S-R-D-L-K-T-A-Y-H-V-T-E-F-F-T-E-D-Q-F-P-G-K-G-H-E-D-E-R-L-F-K-I-G-P-F-Q-Q-V"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-S-L-M-H-R-A-S-R-V-L-P-A-G-G-W-S-G-A-A-D-H-I-A-L-D-Y-E-A-R-F-L-R-R-K-R-L-V-A-A-S-G-A-E-F-L-V-D-L-P-E-V-T-N-L-R-G-G-E-A-F-A-L-E-D-G-R-L-I-E-V-R-C-G-L-E-P-V-L-V-V-T-G-D-L-T-R-L-A-W-H-V-G-N-R-H-T-P-C-Q-I-E-P-D-R-L-L-I-R-D-D-H-V-L-E-T-M-L-R-G-L-G-A-R-V-E-R-R-M-E-P-F-R-P-E-S-G-A-Y-G-S-G-R-T-M-G-H-D-H-G-P-F-H-V-H-A"} +{"text": "### FUNCTION Probable thiol-disulfide oxidoreductase that may be involved in the redox regulation of a number of cytosolic enzymes ### SEQUENCE -M-G-S-C-V-G-K-E-R-S-D-E-E-D-K-I-D-F-K-G-G-N-V-H-V-I-S-N-K-E-N-W-D-H-K-I-A-E-A-N-K-D-G-K-I-V-I-A-N-F-S-A-A-W-C-G-P-C-R-V-I-A-P-V-Y-A-E-M-S-Q-T-Y-P-Q-F-M-F-L-T-I-D-V-D-E-L-M-D-F-S-S-S-W-D-I-R-A-T-P-T-F-F-F-L-K-N-G-E-Q-V-D-K-L-V-G-A-N-K-P-E-L-E-K-K-V-A-A-L-A-D-S-A"} +{"text": "### FUNCTION Involved in endosomal protein transport ### SEQUENCE -M-A-D-V-P-G-Y-L-R-T-C-L-D-M-G-K-I-A-F-L-A-I-L-V-S-T-G-I-V-L-Q-I-L-A-C-A-L-F-N-N-W-W-P-M-L-S-V-I-M-Y-V-L-L-P-M-P-L-L-F-F-G-G-S-D-S-T-S-L-F-N-E-S-D-N-S-W-I-N-A-A-K-F-L-T-G-A-S-A-V-G-S-V-A-I-P-S-I-L-K-H-A-G-L-I-G-W-G-A-L-A-L-D-L-S-S-Y-V-V-F-L-V-A-I-L-G-Y-I-C-I-G-D-A-S-D-N-Y-Y-S-Y-I"} +{"text": "### FUNCTION This protein binds to a specific region on the 26S rRNA ### SEQUENCE -M-S-P-A-K-V-D-V-T-K-K-S-D-A-K-A-Q-A-L-K-T-A-K-A-V-K-S-G-T-T-K-F-K-K-V-K-K-I-R-T-S-V-T-F-H-R-P-R-T-L-T-K-D-R-N-P-K-Y-P-R-I-S-A-T-P-R-N-K-L-D-Q-Y-Q-I-L-K-Y-P-L-T-T-E-S-A-M-K-K-I-E-D-N-N-T-L-V-F-I-V-D-I-R-A-N-K-K-K-I-K-D-A-V-K-K-M-Y-D-I-Q-T-K-K-V-N-T-L-I-R-P-D-G-T-K-K-A-Y-V-R-L-T-P-D-Y-D-A-L-D-V-A-N-K-I-G-I-I"} +{"text": "### FUNCTION Probable cyclin-dependent protein kinase inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle ### SEQUENCE -M-M-S-A-S-P-E-F-Y-K-P-A-P-V-F-S-P-C-S-S-P-L-R-L-L-Q-Q-Q-H-G-E-D-H-Q-E-E-Y-G-Y-G-S-S-G-G-C-C-R-T-P-T-G-G-E-S-N-L-K-A-P-G-T-C-P-P-A-P-R-K-P-R-A-P-A-A-P-C-R-K-R-L-F-E-V-E-V-L-S-L-R-L-E-E-L-E-R-L-F-W-R-P-P-P-P-P-P-T-T-Q-P-Q-P-Q-P-Q-Q-P-P-Q-K-R-R-R-V-A-K-L-G-S"} +{"text": "### FUNCTION Involved in self-incompatibility ### SEQUENCE -M-R-C-S-V-L-F-V-V-S-Y-V-I-M-S-L-L-I-S-H-V-Q-G-M-E-D-Q-K-W-K-K-V-C-N-L-E-G-N-F-P-G-R-C-V-G-N-G-D-E-Q-C-K-R-D-L-T-E-D-G-N-N-P-S-K-C-R-C-R-F-R-A-G-R-R-H-C-R-C-I-Y-C-E-V-F-G-M"} +{"text": "### FUNCTION Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts ### SEQUENCE -M-S-D-E-E-H-H-F-E-S-K-A-D-A-G-A-S-K-T-F-P-Q-Q-A-G-T-I-R-K-N-G-Y-I-V-I-K-N-R-P-C-K-V-M-E-V-S-T-S-K-T-G-K-H-G-H-A-K-C-H-F-V-G-I-D-I-F-N-G-K-K-L-E-D-I-V-P-S-S-H-N-C-D-V-P-H-V-N-R-T-D-Y-Q-L-I-D-I-S-E-D-G-F-V-S-L-L-T-E-T-G-N-T-K-D-D-L-R-L-P-T-D-E-N-L-L-S-Q-I-K-D-G-F-A-E-G-K-D-L-V-V-S-V-M-S-A-M-G-E-E-R-I-C-S-L-K-D-I-G-P-K-N"} +{"text": "### FUNCTION Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts ### SEQUENCE -M-S-D-E-E-H-H-F-E-S-K-A-D-A-G-A-S-K-T-Y-P-Q-Q-A-G-T-I-R-K-N-G-Y-I-V-I-K-G-R-P-C-K-V-V-E-V-S-T-S-K-T-G-K-H-G-H-A-K-C-H-F-V-A-I-D-I-F-N-A-K-K-L-E-D-I-V-P-S-S-H-N-C-D-V-P-H-V-N-R-T-D-Y-Q-L-I-D-I-S-E-D-G-F-V-S-L-L-T-E-N-G-N-T-K-D-D-L-R-L-P-T-D-D-T-L-L-N-Q-V-K-G-G-F-E-E-G-K-D-L-V-L-S-V-M-S-A-M-G-E-E-Q-I-C-A-V-K-D-I-G-T-K-T"} +{"text": "### FUNCTION Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts ### SEQUENCE -M-S-D-E-E-H-Q-F-E-S-K-A-D-A-G-A-S-K-T-Y-P-Q-Q-A-G-T-I-R-K-N-G-Y-I-V-I-K-G-R-P-C-K-V-V-E-V-S-T-S-K-T-G-K-H-G-H-A-K-C-H-F-V-A-I-D-I-F-T-G-K-K-L-E-D-I-V-P-S-S-H-N-C-D-V-P-H-V-N-R-T-D-Y-Q-L-I-D-I-S-E-D-G-F-V-S-L-L-T-D-N-G-N-T-K-D-D-L-R-L-P-T-D-E-N-L-L-S-L-I-K-D-G-F-A-E-G-K-D-L-V-V-S-V-M-S-A-M-G-E-E-Q-I-N-A-L-K-D-I-G-P-K"} +{"text": "### FUNCTION Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts ### SEQUENCE -M-S-D-E-E-H-H-F-E-S-K-A-D-A-G-A-S-K-T-F-P-Q-Q-A-G-T-I-R-K-N-G-Y-I-V-I-K-G-R-P-C-K-V-V-E-V-S-T-S-K-T-G-K-H-G-H-A-K-C-H-F-V-A-I-D-I-F-N-G-K-K-L-E-D-I-V-P-S-S-H-N-C-D-V-P-H-V-N-R-T-D-Y-Q-L-I-D-I-S-E-D-G-F-V-S-L-L-T-E-S-G-N-T-K-D-D-L-R-L-P-T-D-E-N-L-L-K-Q-V-K-D-G-F-Q-E-G-K-D-L-V-V-S-V-M-S-A-M-G-E-E-Q-I-N-A-V-K-D-V-G-T-K-N"} +{"text": "### FUNCTION Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts ### SEQUENCE -M-S-D-E-E-H-H-F-E-S-K-A-D-A-G-A-S-K-T-Y-P-Q-Q-A-G-T-I-R-K-G-G-H-I-V-I-K-N-R-P-C-K-V-V-E-V-S-T-S-K-T-G-K-H-G-H-A-K-C-H-F-V-A-I-D-I-F-T-G-K-K-L-E-D-I-V-P-S-S-H-N-C-D-V-P-H-V-N-R-T-D-Y-Q-L-I-D-I-S-E-D-G-F-V-S-L-L-T-E-N-G-N-T-K-D-D-L-R-L-P-T-D-D-T-L-L-A-Q-V-K-D-G-F-A-E-G-K-D-L-V-L-S-V-M-S-A-M-G-E-E-Q-I-C-G-I-K-D-I-G-P-K"} +{"text": "### FUNCTION Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts ### SEQUENCE -M-S-D-D-D-H-H-F-E-S-S-A-D-A-G-A-S-K-T-Y-P-Q-Q-A-G-T-I-R-K-S-G-H-I-V-I-K-N-R-P-C-K-V-V-E-V-S-T-S-K-T-G-K-H-G-H-A-K-C-H-F-V-A-I-D-I-F-N-G-K-K-L-E-D-I-V-P-S-S-H-N-C-D-V-P-H-V-N-R-V-D-Y-Q-L-L-D-I-T-E-D-G-F-V-S-L-L-T-D-S-G-D-T-K-D-D-L-K-L-P-A-D-E-A-L-V-K-Q-M-K-E-G-F-E-A-G-K-D-L-I-L-S-V-M-C-A-M-G-E-E-Q-I-C-A-V-K-D-V-S-G-G-K"} +{"text": "### FUNCTION Actin-depolymerizing protein Severs actin filaments ### SEQUENCE -M-A-F-M-R-S-H-S-N-A-S-S-G-M-G-V-A-P-D-I-R-D-T-F-L-E-L-Q-M-K-K-A-F-R-Y-V-I-F-K-I-E-E-K-Q-K-Q-V-V-V-E-K-T-G-A-T-T-E-S-Y-D-D-F-L-A-S-L-P-E-N-D-C-R-Y-A-L-Y-D-F-D-F-V-T-G-E-N-V-Q-K-S-K-I-F-F-I-A-W-S-P-S-T-S-R-I-R-A-K-M-L-Y-S-T-S-K-D-R-I-K-Q-E-L-D-G-F-H-Y-E-I-Q-A-T-D-P-T-E-V-D-L-E-V-L-R-E-R-A-H"} +{"text": "### FUNCTION Excisionase and integrase are necessary for the excision of prophage from the host genome by site-specific recombination at the att site ### SEQUENCE -M-Q-H-E-L-Q-P-D-S-L-V-D-L-K-F-I-M-A-D-T-G-F-G-K-T-F-I-Y-D-R-I-K-S-G-D-L-P-K-A-K-V-I-H-G-R-A-R-W-L-Y-R-D-H-C-E-F-K-N-K-L-L-S-R-A-N-G"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-M-K-Q-L-I-R-K-T-R-Q-P-I-R-N-V-T-K-S-P-A-L-R-G-C-P-Q-R-R-G-T-C-T-R-V-Y-T-I-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-I-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-A-V-G-V-K-D-R-Q-Q-G-R-S-K-Y-G-A-K-K-P-K"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-N-G-I-K-Y-A-V-F-T-D-K-S-I-R-L-L-G-K-N-Q-Y-T-S-N-V-E-S-G-S-T-R-T-E-I-K-H-W-V-E-L-F-F-G-V-K-V-K-A-M-N-S-H-R-L-P-A-K-G-R-K-V-R-L-I-M-G-H-T-M-H-Y-R-R-M-I-I-T-L-Q-P-G-Y-S-I-P-P-L-R-K-K-R-T"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-I-A-V-I-T-T-L-L-T-Y-Y-M-S-S-N-N-L-I-T-L-L-I-A-I-E-I-L-L-L-T-V-T-L-K-L-I-H-I-S-G-Y-Y-D-D-I-Y-G-T-I-F-S-L-I-I-I-I-L-A-G-A-E-S-A-I-G-L-S-I-L-V-A-Y-Y-R-L-R-G-T-I-G-H-S-I"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-F-T-F-Y-M-Y-L-A-P-I-V-A-G-V-L-I-G-L-N-W-L-L-A-K-S-N-P-N-I-D-K-A-G-P-F-E-C-G-F-T-S-Y-Q-Q-S-R-A-A-F-S-V-A-F-I-L-V-A-I-L-F-L-P-F-D-L-E-I-S-S-I-L-P-Y-V-T-S-A-Y-N-N-G-L-Y-G-L-I-I-L-I-I-F-L-M-M-L-V-I-A-F-I-L-E-I-Q-L-R-V-L-K-I-E-R-S-Y-D-K-D-R-S-D-S-N-Y-Y-D-H-E-I"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-P-Q-L-V-P-F-Y-W-M-N-L-L-T-T-G-I-A-A-V-S-I-L-L-Y-L-S-A-T-I-I-L-P-N-V-L-R-L-L-V-A-R-A-I-I-V-R-V"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-S-L-I-S-G-I-A-S-I-L-A-I-G-L-L-S-P-V-Q-S-I-L-A-L-I-L-L-F-V-T-V-A-I-N-L-Y-T-S-G-Y-V-L-M-G-I-L-Y-I-L-V-Y-V-G-A-I-A-I-L-F-L-F-I-L-S-L-L-N-I-E-Y-K-P-T-G-G-M-H-P-L-V-I-V-L-I-L-I-P-L-I-P-L-D-I-A-F-E-P-I-A-I-V-E-S-V-S-T-T-Y-N-E-L-S-I-V-G-T-L-F-Y-S-E-Y-A-P-M-L-V-I-I-G-I-I-L-I-V-S-V-I-G-A-I-A-M-T-R"} +{"text": "### FUNCTION Probably a ribosomal protein or a ribosome-associated protein ### SEQUENCE -M-Q-K-F-V-L-K-F-L-W-L-Q-R-S-V-A-V-S-L-D-Q-K-I-G-D-N-V-S-P-L-T-E-F-Y-F-W-P-Q-C-D-A-W-E-E-M-R-N-F-L-E-S-K-S-W-I-N-S-S-E-S-I-L-L-L-N-Q-V-T-E-I-I-N-D-W-Q-E-K-D-D-S-Q-R-K-D-I-F-D-L-K-E-K-F-P-F-V-D-F-I-G-F-D"} +{"text": "### FUNCTION Probably a ribosomal protein or a ribosome-associated protein ### SEQUENCE -M-S-S-F-I-L-K-F-L-W-L-E-K-S-V-A-V-G-L-D-Q-K-I-G-D-R-T-T-P-V-T-E-F-F-F-W-P-Q-H-D-A-W-E-E-M-K-N-F-L-E-D-K-S-W-I-D-Q-S-E-V-V-I-L-L-N-Q-I-T-E-V-I-N-Y-W-Q-E-K-T-E-L-Q-K-R-D-I-S-H-L-T-E-K-F-P-N-V-V-F-V-G-F-D"} +{"text": "### FUNCTION Probably a ribosomal protein or a ribosome-associated protein ### SEQUENCE -M-Q-K-F-V-W-K-V-V-C-L-E-N-K-I-A-I-C-L-D-Q-Q-L-A-D-K-T-S-P-V-T-E-Y-F-F-W-P-Q-S-D-A-W-D-E-L-N-K-L-L-E-S-K-P-W-I-T-L-S-N-R-I-F-V-L-N-I-L-T-D-L-I-N-Y-W-D-E-K-K-S-F-D-Q-S-D-W-P-L-L-K-E-K-F-P-D-V-V-F-I-Y-I-K"} +{"text": "### FUNCTION Probably a ribosomal protein or a ribosome-associated protein ### SEQUENCE -M-E-R-F-V-L-K-F-L-L-I-D-K-V-I-A-V-C-L-D-Q-K-I-S-N-E-R-L-N-P-L-T-E-Y-F-F-W-P-Q-R-D-A-W-E-D-M-K-N-F-I-D-N-N-D-W-I-D-P-K-D-A-V-N-I-L-N-R-I-T-E-V-I-N-F-W-E-E-S-A-Q-L-K-K-E-D-I-K-N-L-N-I-K-F-P-D-C-V-F-I-V-M"} +{"text": "### FUNCTION Probably a ribosomal protein or a ribosome-associated protein ### SEQUENCE -M-K-K-E-L-I-L-K-F-L-W-L-E-K-S-I-A-V-C-L-D-Q-K-V-G-D-S-I-T-P-L-T-E-F-F-F-W-P-Q-K-D-A-W-E-E-M-K-N-F-L-E-S-Q-S-W-I-T-Q-S-D-S-V-N-L-L-N-N-I-T-E-V-I-N-F-W-Q-E-R-D-T-N-V-I-D-R-K-H-I-S-N-L-R-E-K-F-P-D-I-I-V-I-G-Q"} +{"text": "### FUNCTION Manganese-binding polypeptide with L-arginine metabolizing enzyme activity Component of the core of photosystem II ### SEQUENCE -P-V-L-A-A-A-S-W-A-L-F-N-I-G-R-L-A-L-Q-Q-F-N-K-I-A-S-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-L-T-K-N-P-F-V-A-N-R-L-L-R-K-I-N-N-L-N-T-K-S-E-K-E-I-I-I-T-W-S-R-T-S-T-I-I-P-A-M-I-G-H-T-I-A-I-H-N-G-K-E-H-L-P-I-Y-V-T-D-R-M-V-G-H-K-L-G-E-F-S-P-T-L-N-F-R-G-H-A-K-N-D-N-R-S-R-R"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-P-Q-T-H-L-N-V-A-D-N-S-G-A-R-K-L-M-C-I-R-I-I-G-A-S-N-R-R-Y-A-Y-I-G-D-I-V-V-A-V-I-K-E-A-V-P-N-T-P-L-E-R-S-E-V-I-R-A-V-I-V-R-T-C-K-E-L-K-R-S-N-G-I-I-I-Q-Y-D-D-N-A-A-V-V-I-D-Q-E-G-N-P-K-G-T-R-I-F-C-A-I-A-R-E-L-R-Q-F-N-F-T-K-I-V-S-L-A-P-E-I-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-K-D-T-I-A-D-I-I-T-S-I-R-N-A-D-M-N-R-K-R-T-V-Q-I-P-F-T-N-I-T-E-N-T-V-K-I-L-L-R-E-G-F-I-E-N-V-R-K-H-R-E-S-D-K-S-F-L-V-L-T-L-R-Y-R-R-N-T-K-G-S-Y-K-T-F-L-N-L-K-R-I-S-T-P-G-L-R-I-Y-Y-N-Y-Q-K-I-P-R-I-L-G-G-M-G-I-V-I-L-S-T-S-R-G-I-M-T-D-R-E-A-R-L-E-K-I-G-G-E-V-L-C-Y-I-W"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-G-V-T-K-K-P-D-L-N-D-P-V-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-V-V-I-L-G-T-I-A-C-N-V-G-L-A-V-L-E-P-S-M-I-G-E-P-A-D-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-F-P-V-F-Q-I-L-R-T-V-P-N-K-L-L-G-V-L-L-M-V-S-V-P-A-G-L-V-T-V-P-F-L-E-N-V-N-K-F-Q-N-P-F-R-R-P-V-A-T-T-V-F-L-I-G-T-A-V-S-L-W-L-G-I-G-A-T-L-P-I-E-K-S-L-T-L-G-L-F"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-I-K-R-G-Y-I-A-R-K-R-R-T-K-I-R-L-F-T-S-S-F-R-G-A-H-S-R-L-T-R-T-I-S-Q-Q-K-I-K-A-L-V-S-A-H-R-D-R-N-R-K-K-R-E-F-R-G-L-W-I-S-R-I-N-A-G-I-G-D-N-D-K-K-K-N-I-Y-Y-S-Y-S-N-F-M-Y-N-L-Y-K-K-Q-L-L-L-N-R-K-I-V-A-Q-I-A-I-F-K-G-N-C-L-F-M-I-A-N-E-I-I-T"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-R-D-L-K-T-Y-L-S-V-A-P-V-V-S-T-L-W-F-A-A-L-A-G-L-L-I-E-I-N-R-L-F-P-D-A-L-I-F-P-F-F-S-F"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex ### SEQUENCE -M-P-T-I-T-S-Y-F-G-F-L-L-A-V-L-T-I-T-S-G-L-F-I-S-L-R-K-L-R-L-I"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-D-T-T-G-R-I-P-L-W-I-I-G-T-V-T-G-I-T-V-I-G-L-I-G-I-F-F-Y-G-S-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-T-W-I-S-E-D-T-W-Q-S-E-E-V-R-V-D-F-V-T-G-C-R-N-P-R-D-F-F-W-A-F-I-T-L-L-G-S-V-G-F-L-L-V-A-A-S-S-Y-L-H-K-N-F-L-S-F-I-S-S-E-F-D-S-E-L-I-R-F-L-P-Q-G-A-T-I-T-V-Y-G-T-A-G-L-F-V-S-L-F-L-W-L-T-I-F-W-N-V-G-S-G-Y-D-L-F-D-K-K-R-G-I-V-C-I-F-R-Y-G-F-P-G-K-N-R-R-I-F-I-R-V-L-I-N-D-I-Q-S-L-I-I-Q-S-K-K-E-N-K-K-E-G-R-Y-L-R-S-G-V-L-Y-M-Q-T-R-E-Q-G-A-I-P-L-T-A-V-D-D-S-W-N-P-P-K-I-A-Q-K-A-G-D-L-S-K-L-L-R-V-P-I-E-I-F"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-T-N-L-P-S-I-F-V-P-L-V-G-L-V-F-P-A-M-A-M-A-S-L-F-L-Y-L-Q-K-N-K-I-F"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-I-N-I-V-S-L-V-C-I-Y-I-N-S-V-P-Y-S-S-I-F-F-L-D-K-L-P-E-A-Y-A-F-L-N-P-I-V-D-I-M-P-V-I-P-L-F-F-F-L-L-A-F-V-W-Q-A-A-V-S-F-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-N-I-T-D-P-F-P-C-L-G-Y-W-P-S-A-G-S-F-G-F-N-T-D-I-L-A-T-N-P-I-N-L-S-I-V-I-G-V-L-I-F-F-G-K-G-V-L-S-D-L-L-D-N-R-K-Q-R-I-L-R-T-I-R-N-S-E-E-L-R-E-G-A-I-E-Q-L-E-K-A-Q-A-R-L-K-K-V-E-T-E-A-D-R-F-R-V-N-G-Y-S-E-I-E-R-E-K-L-N-L-I-N-S-I-Y-T-T-L-E-Q-L-E-N-Y-K-N-E-T-I-H-F-E-Q-Q-R-A-I-N-Q-V-R-Q-R-V-L-Q-Q-A-L-Q-G-A-L-G-T-L-N-S-C-L-N-N-E-L-H-F-R-T-I-A-A-N-I-G-M-F-G-A-M-K-E-K-N-N"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -M-T-I-A-F-Q-L-A-V-F-A-L-I-A-T-S-S-I-L-L-I-S-V-P-V-V-F-A-S-P-D-G-W-S-S-N-K-N-V-V-F-S-G-T-S-L-W-I-A-L-V-F-L-V-G-I-L-N-S-L-I-S"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-R-K-S-L-I-Q-R-E-K-K-R-Q-K-L-E-Q-K-Y-H-L-I-R-R-S-S-K-K-E-I-S-K-V-P-S-L-S-E-K-W-K-I-H-G-K-L-E-S-L-P-R-N-S-A-P-T-R-L-H-R-R-C-F-S-T-G-R-P-R-A-N-Y-R-D-F-G-L-S-G-H-T-L-R-E-M-V-H-E-C-L-L-P-G-A-T-R-S-S-W"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-R-I-N-G-N-F-I-D-K-T-F-S-V-V-A-N-I-L-L-Q-I-I-P-T-T-S-G-E-K-E-A-F-T-Y-Y-R-D-G-M-S-A-Q-S-E-G-N-Y-A-E-A-L-Q-N-Y-Y-E-A-M-R-L-E-V-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-E-H-T-K-A-L-E-Y-Y-F-R-A-L-E-R-N-P-F-L-P-Q-A-F-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-R-Q-G-D-S-E-I-A-E-S-W-F-D-Q-A-A-E-Y-W-K-Q-A-I-A-L-T-P-G-N-Y-I-E-A-Q-N-W-L-K-I-T-R-R-F-E"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-T-L-N-L-C-V-L-T-P-N-R-I-V-W-D-S-D-V-K-E-I-I-L-S-T-N-S-G-Q-V-G-I-L-P-N-H-A-P-L-A-M-A-L-D-I-G-I-L-R-I-R-L-N-D-Q-W-L-T-M-A-L-M-G-G-F-A-R-I-G-N-N-E-I-T-V-L-V-N-D-A-E-K-G-S-D-I-D-P-Q-E-A-Q-Q-T-L-E-I-A-E-A-N-L-K-E-A-K-G-K-R-Q-T-I-E-A-N-L-A-L-R-R-A-R-T-R-V-E-S-I-N-M-I-S"} +{"text": "### FUNCTION Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids ### SEQUENCE -M-E-M-L-Q-G-L-L-L-L-W-L-L-L-N-V-G-G-V-W-T-S-R-G-P-L-R-P-L-C-R-P-I-N-A-T-L-A-A-E-N-E-A-C-P-V-C-V-T-F-T-T-T-I-C-A-G-Y-C-P-S-M-M-R-V-L-P-A-A-L-P-P-V-P-Q-P-V-C-T-Y-R-E-L-R-F-A-S-V-R-L-P-G-C-P-P-G-V-D-P-V-V-S-F-P-V-A-L-S-C-R-C-G-P-C-R-L-S-S-S-D-C-G-G-P-R-A-Q-P-L-A-C-D-R-P-P-L-P-G-L-P-F-L"} +{"text": "### FUNCTION Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule ### SEQUENCE -M-D-A-V-A-V-Y-H-G-K-I-S-R-E-T-G-E-K-L-L-L-A-T-G-L-D-G-S-Y-L-L-R-D-S-E-S-V-P-G-V-Y-C-L-C-V-L-Y-H-G-Y-I-Y-T-Y-R-V-S-Q-T-E-T-G-S-W-S-A-E-T-A-P-G-V-H-K-R-Y-F-R-K-I-K-N-L-I-S-A-F-Q-K-P-D-Q-G-I-V-I-P-L-Q-Y-P-V-E-K-S-S-P-R-S-T-Q-G-T-T-G-I-R-E-D-P-D-V-C-L-K-A-P"} +{"text": "### FUNCTION May be involved in induction of apoptosis in CD4 T-cells or hepatocytes ### SEQUENCE -M-A-A-P-R-G-R-A-A-P-W-T-T-A-L-L-L-L-L-T-S-Q-I-L-S-P-G-S-C-A-D-E-E-E-V-P-E-E-W-V-L-L-H-V-V-Q-G-Q-I-G-A-G-N-Y-S-Y-L-R-L-N-H-E-G-K-I-V-L-R-M-R-S-L-K-G-D-A-D-L-Y-V-S-A-S-S-L-H-P-S-F-D-D-Y-E-L-Q-S-A-T-C-G-P-D-A-V-S-I-P-A-H-F-R-R-P-V-G-I-G-V-Y-G-H-P-S-H-L-E-S-E-F-E-M-K-V-Y-Y-D-G-T-V-E-Q-H-P-F-G-E-A-A-Y-P-A-D-G-A-D-A-G-Q-K-H-A-R-A-P-E-D-A-S-Q-E-E-E-S-V-L-W-T-I-L-I-S-V-L-K-L-V-L-E-I-L-F"} +{"text": "### FUNCTION Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta ### SEQUENCE -M-G-K-G-C-K-V-V-V-C-G-L-L-S-V-G-K-T-A-I-L-E-Q-L-L-Y-G-N-H-T-I-G-M-E-D-C-E-T-M-E-D-V-Y-M-A-S-V-E-T-D-R-G-V-K-E-Q-L-H-L-Y-D-T-R-G-L-Q-E-G-V-E-L-P-K-H-Y-F-S-F-A-D-G-F-V-L-V-Y-S-V-N-N-L-E-S-F-Q-R-V-E-L-L-K-K-E-I-D-K-F-K-D-K-K-E-V-A-I-V-V-L-G-N-K-I-D-L-S-E-Q-R-Q-V-D-A-E-V-A-Q-Q-W-A-K-S-E-K-V-R-L-W-E-V-T-V-T-D-R-K-T-L-I-E-P-F-T-L-L-A-S-K-L-S-Q-P-Q-S-K-S-S-F-P-L-P-G-R-K-N-K-G-N-S-S-S-E-N"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-S-V-T-A-V-N-T-R-G-E-L-E-N-L-F-L-R-A-S-H-E-M-N-S-E-A-S-K-L-D-K-K-V-C-V-D-G-G-T-F-C-G-F-P-K-I-G-G-P-C-C-S-G-W-C-I-F-V-C-L"} +{"text": "### FUNCTION Gamma-conotoxins may act on voltage-gated non-specific cation pacemaker channels ### SEQUENCE -M-E-K-L-T-I-L-L-L-V-A-A-V-L-L-S-I-Q-A-L-N-Q-E-K-H-Q-R-A-K-I-N-L-L-S-K-R-K-P-P-A-E-R-W-W-R-W-G-G-C-M-A-W-F-G-L-C-S-K-D-S-E-C-C-S-N-S-C-D-V-T-R-C-E-L-M-P-F-P-P-D-W"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-T-R-F-R-Q-T-R-R-R-R-G-H-V-S-M-G-Y-G-R-I-G-K-H-R-K-Q-R-G-G-R-G-N-A-G-G-Q-H-H-R-K-T-W-F-T-T-F-H-P-D-Y-F-G-K-H-G-M-R-V-F-H-L-K-A-N-K-Y-Y-C-P-S-I-N-V-D-S-L-W-S-L-V-G-K-D-V-Q-A-Q-Y-K-N-A-K-V-G-E-E-V-P-V-I-D-C-V-K-H-G-Y-F-K-V-L-G-K-G-F-L-P-K-Q-P-V-I-V-R-A-R-Y-F-S-E-K-A-Q-Q-K-I-K-A-V-G-G-A-C-E-L-T-A"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-T-R-F-R-Q-T-R-R-R-R-G-H-V-S-M-G-Y-G-R-I-G-K-H-R-K-Q-R-G-G-R-G-N-A-G-G-Q-H-H-R-K-T-W-F-T-T-F-H-P-D-Y-F-G-K-H-G-M-R-V-F-H-L-K-A-N-K-Y-Y-C-P-S-I-N-V-D-S-L-W-S-L-V-G-K-D-V-Q-E-Q-Y-K-N-A-K-T-G-E-E-V-P-V-I-D-C-V-K-H-G-Y-F-K-V-L-G-K-G-F-L-P-K-Q-P-V-I-V-R-A-R-Y-F-S-E-K-A-Q-Q-K-I-K-A-V-G-G-A-C-E-L-T-A"} +{"text": "### FUNCTION Allows the formation of correctly charged Gln-tRNA ### SEQUENCE -M-N-L-I-F-T-R-I-I-R-R-F-G-E-G-K-R-K-T-P-F-P-G-D-P-I-L-V-P-D-E-P-Y-D-S-K-I-Q-E-S-Q-L-S-P-M-P-Q-I-D-A-K-L-I-N-H-L-E-R-L-S-L-V-R-F-D-S-E-Q-A-V-A-N-L-R-S-S-I-R-V-A-K-R-L-E-L-V-D-V-E-G-V-E-P-M-H-T-V-W-E-D-Q-E-C-P-T-F-E-D-V-E-E-D-P-L-P-I-E-E-V-F-R-N-A-S-L-R-F-D-D-F-F-V-T-P-P-G-N-L-P-L-E-S-K-E-R-F-D-L-N-V-I-N-E-W-D-T-I-G-K-P-V-A-P-E-V-K-L-T-R-M-T-E-R-K-K"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-E-P-N-P-S-D-P-V-L-T-D-R-I-Q-A-I-V-T-T-E-K-S-I-D-E-M-M-K-C-A-R-E-I-I-Q-D-L-G-K-E-K-Q-I-G-K-N-K-M-E-D-N-A-N-N-F-K-K-L-I-T-Q-V-E-N-E-L-S-A-Q-M-Q-Y-L-S-H-V-C-V-G-S-S-H-Q-G-S-T-F-G-V-L-Q-N-S-L-L-A-Q-S-G-L-S-S-L-H-S-E-L-F-Q-I-V-R-Y-L-D-P-T-S-D-E-P-Q-T-T-E-E-D-E-E-D-G-S-D-D-L-N-E-D-G-A-D-G-A-P-S-S-T-V-T-S-S-T-T-D-G-S-G-G-G-D-D-A-A-S-S-S-A-P-R-S-Q-E-E-S-G-R-Q-M-T-D-D-D-D-D-M-E-Q"} +{"text": "### FUNCTION Potent inhibitor of insect, but not mammalian, voltage-gated calcium channels ### SEQUENCE -M-K-F-S-K-L-S-I-T-L-A-V-I-L-T-Q-A-V-F-V-L-C-G-M-K-N-E-D-F-M-E-K-G-L-E-S-N-E-L-H-D-A-I-K-K-P-V-N-S-G-K-P-D-T-E-R-L-L-D-C-V-L-S-R-V-C-S-S-D-A-N-C-C-G-L-T-P-T-C-K-M-G-L-C-V-P-K-V-G-G-L-L-G-G-L-L-G-G-I-L"} +{"text": "### FUNCTION Potent inhibitor of insect, but not mammalian, voltage-gated calcium channels ### SEQUENCE -M-K-F-S-K-L-S-I-T-L-A-V-I-L-T-Q-A-V-F-V-L-C-G-M-K-N-E-D-F-M-E-K-G-L-E-S-N-E-L-H-D-A-I-K-K-P-V-N-S-G-K-P-D-T-E-R-L-L-D-C-V-L-S-R-V-C-S-P-D-A-N-C-C-G-L-T-P-I-C-K-M-G-L-C-V-P-K-V-G-G-L-L-G-G-L-L-G-G-I-L"} +{"text": "### FUNCTION Binds voltage-independently at site-3 of sodium channels and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission ### SEQUENCE -M-N-Y-L-V-M-I-S-L-A-L-L-I-A-G-V-D-S-A-R-D-A-Y-I-A-K-N-D-N-C-V-Y-E-C-F-Q-D-S-Y-C-N-D-L-C-T-K-N-G-A-K-S-G-T-C-D-W-I-G-T-Y-G-D-A-C-L-C-Y-A-L-P-D-N-V-P-I-K-L-S-G-E-C-H-R"} +{"text": "### FUNCTION JanA and janB regulate somatic sex differentiation ### SEQUENCE -M-K-M-F-K-S-L-S-L-L-P-R-N-V-S-P-F-Q-K-C-Y-S-T-D-L-I-S-L-V-G-V-P-R-V-K-I-T-K-G-Q-N-R-Y-L-L-V-N-I-H-T-H-G-F-T-K-Y-G-R-V-I-V-R-G-A-D-V-D-N-H-L-T-I-F-D-S-I-L-E-E-L-E-P-Q-G-I-C-A-K-I-L-G-G-G-R-I-L-N-E-A-D-S-K-K-M-K-I-Y-G-T-S-R-T-F-G-S-A-D-H-T-R-T-R-N-I-L-Q-S-W-T-T-Y-K-D-F-K-I-S-V-K-N"} +{"text": "### FUNCTION JanA and janB regulate somatic sex differentiation ### SEQUENCE -M-K-M-F-Q-S-L-S-L-L-P-R-I-V-S-P-F-R-K-C-Y-S-T-D-L-I-S-L-V-G-V-P-R-V-K-I-T-K-G-Q-N-R-Y-L-L-V-N-I-H-T-H-G-F-T-K-Y-G-R-V-I-V-R-G-A-D-V-E-N-H-L-T-I-F-D-S-I-L-E-E-L-E-P-Q-G-I-C-A-K-I-L-G-G-G-R-I-L-N-E-T-D-S-K-K-M-K-I-Y-G-T-S-R-T-F-G-S-A-D-H-T-R-T-R-N-I-L-Q-S-W-T-T-Y-K-D-F-K-I-T-V-K-N"} +{"text": "### FUNCTION JanA and janB regulate somatic sex differentiation ### SEQUENCE -M-K-M-F-K-S-L-S-L-L-P-R-I-V-S-P-F-Q-K-C-Y-S-T-D-L-I-S-L-V-G-I-P-R-V-K-I-T-K-G-Q-N-R-Y-L-L-V-N-I-H-T-H-G-F-T-K-Y-G-R-V-I-V-R-G-A-D-V-D-N-H-L-T-V-F-D-S-I-L-E-E-L-E-P-Q-G-I-C-A-K-I-L-G-G-G-R-I-L-N-E-A-D-S-K-K-I-K-I-Y-G-T-S-R-T-F-G-S-A-D-H-T-R-T-R-N-I-L-H-S-W-T-T-Y-K-D-F-K-I-T-V-K-N"} +{"text": "### FUNCTION JanA and janB regulate somatic sex differentiation ### SEQUENCE -M-K-M-F-K-S-L-S-Q-L-P-R-I-V-S-P-F-Q-K-C-Y-S-T-D-L-I-S-L-V-G-I-P-R-V-K-I-T-K-G-Q-N-R-Y-L-L-V-N-I-H-T-H-G-F-T-K-Y-G-R-V-I-V-R-G-A-D-V-D-N-H-L-T-V-F-D-S-I-L-E-E-L-E-P-Q-G-I-C-A-K-I-L-G-G-G-R-I-L-N-E-A-D-S-K-K-M-K-I-Y-G-T-S-R-T-F-G-S-A-D-H-T-R-T-R-N-I-L-H-S-W-T-T-Y-K-D-F-K-I-T-V-K-N"} +{"text": "### FUNCTION JanA and janB regulate somatic sex differentiation ### SEQUENCE -M-K-M-F-K-S-L-S-L-I-P-R-I-V-S-P-F-Q-K-C-Y-S-T-D-L-I-S-L-V-G-V-P-R-V-K-I-T-K-G-Q-N-R-Y-L-L-V-N-I-H-T-H-G-F-T-K-Y-G-R-V-I-V-R-G-A-D-V-D-N-H-L-A-I-F-D-S-I-L-E-E-L-E-P-E-G-I-C-A-K-I-L-G-G-G-R-I-L-N-E-P-D-N-K-K-I-K-I-Y-G-T-S-R-T-F-G-G-A-D-H-T-R-T-R-N-I-L-Q-A-W-T-T-Y-K-D-F-K-I-T-V-K-Q"} +{"text": "### FUNCTION JanA and janB regulate somatic sex differentiation ### SEQUENCE -M-K-M-L-K-S-L-S-L-I-P-R-I-V-S-P-F-Q-K-C-Y-S-T-D-L-I-S-L-V-G-V-P-R-V-K-I-S-K-G-Q-N-R-Y-L-L-V-N-I-H-T-H-G-F-T-K-Y-G-R-V-I-V-R-G-A-D-V-D-N-H-L-A-I-F-D-S-I-L-E-E-L-E-P-E-G-I-C-A-K-I-L-G-G-G-R-I-L-N-E-P-D-N-K-K-I-K-I-Y-G-T-S-R-T-F-G-G-A-D-H-T-R-T-R-N-I-L-Q-A-W-T-T-Y-K-D-F-K-I-T-V-K-Q"} +{"text": "### FUNCTION JanA and janB regulate somatic sex differentiation ### SEQUENCE -M-K-M-F-K-S-L-S-L-I-P-R-I-V-S-P-F-Q-K-C-Y-S-T-D-L-I-N-L-V-G-V-P-R-V-K-I-T-K-G-Q-N-R-Y-L-L-V-N-I-H-T-H-G-F-T-K-Y-G-R-V-I-V-R-G-A-D-V-D-N-H-L-A-I-F-D-S-I-L-E-E-L-E-P-E-G-I-C-A-K-I-L-G-G-G-R-I-L-N-E-P-D-N-K-K-I-K-I-Y-G-T-S-R-T-F-G-G-A-D-H-T-R-T-R-N-I-L-Q-A-W-T-T-Y-K-D-F-K-I-T-V-K-Q"} +{"text": "### FUNCTION JanA and janB regulate somatic sex differentiation ### SEQUENCE -M-N-R-L-Q-L-L-S-K-G-L-R-L-I-H-K-M-S-E-E-A-L-A-G-V-P-L-V-H-I-S-P-E-G-I-F-K-Y-V-M-I-N-V-I-D-G-G-D-A-S-K-A-V-I-R-G-F-A-D-C-T-W-H-A-D-I-F-D-R-E-E-E-V-F-K-K-L-G-L-R-A-E-C-P-G-G-G-R-I-E-H-N-P-D-K-K-Y-L-K-V-Y-G-Y-S-Q-G-F-G-K-A-D-H-A-Q-T-K-R-I-L-A-T-K-Y-P-D-Y-T-I-E-T-S-D-E-G-Y"} +{"text": "### FUNCTION JanA and janB regulate somatic sex differentiation ### SEQUENCE -M-N-R-F-Q-L-L-S-K-G-L-R-L-I-H-K-M-S-E-E-A-L-A-G-V-P-L-V-H-I-S-P-E-G-I-F-K-Y-V-M-I-N-V-I-D-G-G-D-A-S-K-A-V-I-R-G-F-A-D-C-T-W-H-A-D-I-F-D-R-E-E-E-V-F-K-K-L-G-L-R-A-E-C-P-G-G-G-R-I-E-H-N-P-D-K-K-Y-L-K-V-Y-G-Y-S-Q-G-F-G-K-A-D-H-A-Q-T-K-R-I-L-A-T-K-Y-P-D-Y-T-I-E-T-S-D-E-G-Y"} +{"text": "### FUNCTION JanA and janB regulate somatic sex differentiation ### SEQUENCE -M-N-R-L-Q-L-L-S-K-G-L-R-L-I-H-K-M-S-E-E-A-L-A-G-V-P-L-V-H-I-S-P-E-G-I-F-K-Y-V-M-I-N-V-I-D-G-G-D-A-S-K-A-V-I-R-G-F-A-D-C-T-W-H-A-D-I-F-E-R-E-E-D-V-F-K-K-L-G-L-R-A-E-C-P-G-G-G-R-I-E-H-N-P-D-K-K-Y-L-K-V-Y-G-Y-S-Q-G-F-G-K-A-D-H-A-Q-T-K-R-I-L-A-T-K-Y-P-D-Y-T-I-E-I-S-D-E-G-Y"} +{"text": "### FUNCTION JanA and janB regulate somatic sex differentiation ### SEQUENCE -M-N-R-F-Q-L-L-S-K-G-L-R-L-I-H-K-M-S-E-E-A-L-A-G-V-P-L-V-H-I-S-P-E-G-I-F-K-Y-V-M-I-N-V-I-D-G-G-D-A-S-K-A-V-I-R-G-F-A-D-C-T-W-H-A-D-I-F-E-R-E-E-E-V-F-K-K-L-G-L-R-A-E-C-P-G-G-G-R-I-E-H-N-P-D-K-K-Y-L-K-V-Y-G-Y-S-Q-G-F-G-K-A-D-H-A-Q-T-K-R-I-L-A-T-K-Y-P-D-Y-T-I-E-I-S-D-E-G-Y"} +{"text": "### FUNCTION May play a role in the acquisition, storage, and transport of lipids, and may be important to the organism since it is incapable of synthesizing most of its lipids de novo ### SEQUENCE -M-E-P-F-I-G-T-W-K-M-E-K-S-E-G-F-D-K-I-M-E-R-L-G-V-D-Y-F-T-R-K-M-G-N-M-M-K-P-N-L-I-I-S-D-L-G-D-G-R-Y-N-M-R-S-E-S-K-F-K-T-S-E-F-S-F-K-L-G-E-Q-F-K-E-V-T-P-D-S-R-E-V-M-S-M-L-T-V-E-D-G-V-L-K-Q-E-Q-V-G-K-D-K-T-T-Y-I-D-R-V-V-Y-G-N-E-L-R-A-T-V-K-A-D-E-L-V-C-V-R-T-Y-S-R-G-M"} +{"text": "### FUNCTION Ribosomal protein P0 is the functional equivalent of Ecoli protein L10 ### SEQUENCE -A-P-H-S-I-A-N-G-F-K-N-L-L-A-L-A-A-T-T-D-V-D-S-K-E-A-E-T-I-K-E-Y-I-K-D-P-S-K-I-A-A-A-A-A-A-T-A-P-A-A-E-T-K-K-E-E-K-K-E-E-K-K-E-E-T-E-E-S-D-D-D-I-G-L-S-L-F-H"} +{"text": "### FUNCTION Blocks Kv16/KCNA6 potassium channels ### SEQUENCE -R-C-H-F-V-I-C-T-T-D-C-R-R-N-S-P-G-T-Y-G-E-C-V-K-K-E-K-G-K-E-C-V-C-K-S"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-V-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-F-V-T-A-D-D-S-I-S-A-L-E-D-L-F-A-K-A-H-D-K-M-E-N-S-E-A-S-P-L-N-E-R-D-C-R-A-L-G-E-Y-C-G-L-P-Y-V-H-N-S-R-C-C-S-Q-L-C-G-F-I-C-V-P-E-S-P"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-F-V-T-A-D-S-R-N-G-L-E-Y-L-F-P-K-A-H-Y-E-M-N-P-E-A-S-K-L-N-K-K-R-D-C-V-A-G-G-H-F-C-G-F-P-K-I-G-G-P-C-C-S-G-W-C-F-F-V-C-A"} +{"text": "### FUNCTION Gamma-conotoxins may act on voltage-gated non-specific cation pacemaker channels ### SEQUENCE -M-E-K-L-T-I-L-L-L-V-A-A-V-L-M-S-T-Q-A-L-N-Q-E-Q-H-Q-R-A-K-I-N-L-L-S-K-R-K-P-P-A-E-R-W-W-E-C-G-I-W-F-S-R-C-T-K-D-S-E-C-C-S-N-S-C-D-Q-T-Y-C-E-L-M-P-F-P-P-D-W"} +{"text": "### FUNCTION Chi-conotoxins inhibit the neuronal noradrenaline transporter ### SEQUENCE -M-R-C-L-P-V-F-V-I-L-L-L-L-T-A-S-G-P-S-V-D-A-K-V-H-L-K-T-K-G-D-G-P-L-S-S-F-R-D-N-A-K-S-T-L-Q-R-L-Q-D-K-S-T-C-C-G-Y-R-M-C-V-P-C-G"} +{"text": "### FUNCTION Has a role in meiosis ### SEQUENCE -M-G-S-P-S-L-T-K-T-I-N-A-S-L-S-L-H-S-I-T-Q-P-I-T-L-L-K-T-M-H-Y-V-L-Q-L-T-I-L-P-S-A-M-Q-H-Y-A-T-L-R-N-F-T-H-P-A-C-S-V-N-K-Q-A-E-Q-G-K-E-Q-Q-Q-Y-A-M-K-S-Q-F-Q-F-R-S-G-I-C-S-K-V-R-S-D-E-L-G-F-K-G-N-S-L-Q-L-N-D-L-P-K-N-P-Y"} +{"text": "### FUNCTION Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol ### SEQUENCE -M-R-L-T-T-F-I-Y-A-I-T-C-L-P-I-F-I-S-A-S-S-W-F-S-S-F-S-F-G-E-S-K-S-T-D-L-V-S-S-T-S-E-K-I-P-G-A-N-P-A-S-Y-C-A-D-W-D-R-G-D-D-H-V-V-V-D-Y-I-N-L-I-P-N-P-P-A-A-G-K-N-L-T-I-E-T-E-I-N-V-G-T-T-V-L-N-G-S-Y-V-D-I-Q-V-K-Y-G-F-V-R-I-V-N-E-R-L-D-I-C-D-K-A-Y-E-L-A-A-V-E-C-P-V-E-P-G-I-I-T-K-Q-A-T-I-S-L-P-W-A-I-P-P-G-R-Y-H-V-L-A-T-A-Y-N-A-D-G-E-Q-L-T-C-V-S-A-S-V-S-F-S-H-F-G-F-Q-L-I-N-Q-D-H"} +{"text": "### FUNCTION Involved in ribosome biogenesis Required for normal pre-rRNA processing in internal transcribed spacer 1 ### SEQUENCE -M-P-K-A-K-K-R-V-S-L-A-S-K-A-S-S-R-L-P-S-S-G-K-P-S-Q-Q-A-S-I-P-N-V-E-L-S-S-T-V-T-S-N-S-Q-V-L-N-N-D-P-L-K-E-T-K-K-D-K-R-K-D-R-H-F-N-W-Q-Q-K-F-S-N-P-K-I-S-A-S-A-R-K-R-R-N-R-K-A-R-E-N-L-K-V-N-V-S-S-I-G-E-V-L-P-E-I-D-L-D-I-S-V-A-N-S-R-L-K-P-V-I-K-D-S-L-S-S-K-Q-T-K-S-S-M-K-R-N-T-V-E-E-I-E-R-F-Q-A-I-L-K-H-P-S-F-V-S-N-P-L-E-T-V-R-E-H-L-G-N-S-L-D-S-R"} +{"text": "### FUNCTION Has a role in meiosis ### SEQUENCE -M-Y-P-K-I-V-A-R-C-M-I-V-I-T-K-N-R-E-S-E-R-N-V-L-I-C-Y-R-N-V-T-N-V-Y-F-S-L-R-I-L-L-N-R-Q-N-E-G-N-N-C-K-Y-K-L-V-F-S-L-Y-R-V-S-F-R-R-M-R-L-N-D-R-Q-L-S-C-V-E-S-V-T-N-G-I-G-L-L-C-L-K-Q-A-D-Q-V-C-L-F-T-P-T-V-D-S-H-L"} +{"text": "### FUNCTION Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps ### SEQUENCE -M-N-F-P-G-M-P-G-G-A-A-P-S-G-G-A-A-P-G-G-Y-D-P-N-D-P-N-I-K-M-M-Q-K-A-M-E-S-C-F-A-K-T-V-M-S-G-G-A-G-F-A-L-G-G-V-F-G-M-F-M-A-S-M-A-Y-D-T-P-Y-H-S-P-T-T-P-G-T-G-P-G-A-N-P-A-A-A-G-I-P-G-Y-K-P-V-D-L-S-S-M-P-L-K-E-Q-L-K-H-G-F-K-D-M-G-Q-R-S-Y-S-T-A-K-N-F-A-K-V-G-A-L-F-S-G-I-E-C-G-I-E-G-L-R-A-K-N-D-L-G-N-G-V-A-A-G-C-L-T-G-A-I-L-A-K-N-G-G-P-Q-A-A-A-V-G-C-A-G-F-A-A-F-S-A-A-I-D-A-W-M-R-M-P-S-E-E-D"} +{"text": "### FUNCTION Plays a role in the regulation of membrane potential Could mediate a proton leak Regulated by the spc1-atf1 pathway and so expression is stress-induced ### SEQUENCE -M-A-L-T-G-S-D-I-F-K-V-I-F-A-I-I-L-P-P-L-G-V-F-L-E-R-G-C-G-A-D-V-I-I-N-I-L-L-C-C-L-G-Y-V-P-G-I-I-H-A-L-Y-I-I-L-K-Y"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-P-P-K-F-D-P-N-E-V-K-V-I-T-L-R-A-T-G-G-E-V-G-A-S-S-A-L-A-P-K-I-G-P-L-G-L-S-P-K-K-V-G-E-D-I-A-K-A-T-G-D-W-K-G-L-R-V-T-V-K-L-T-I-Q-N-R-Q-A-A-V-S-V-V-P-T-A-S-A-L-V-I-R-A-L-K-E-P-P-R-D-R-K-K-E-K-N-I-K-H-N-K-S-V-S-F-D-E-I-V-E-I-A-R-T-M-R-F-K-S-F-S-K-E-L-K-G-T-V-L-E-V-L-G-T-A-F-S-V-G-C-Q-V-D-G-K-S-P-K-A-V-Q-E-A-I-H-A-G-E-I-D-V-P-E-E"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-P-Q-E-I-G-D-I-K-K-F-I-E-I-C-R-R-K-D-A-S-A-A-R-I-K-K-N-K-A-T-Q-Q-I-K-F-K-V-R-C-Q-K-Y-L-Y-T-L-V-L-K-D-S-D-K-A-E-K-L-K-A-S-L-P-P-S-L-T-I-A-D-V-A-K-R-N-K-K-Q-T-A"} +{"text": "### FUNCTION Necessary for protein translocation in the endoplasmic reticulum ### SEQUENCE -M-A-D-Q-I-Q-E-I-L-D-V-P-R-E-F-L-K-D-G-I-Q-F-I-K-K-C-Q-K-P-D-R-R-E-F-I-K-I-S-Q-A-V-G-T-G-F-L-I-M-G-A-V-G-Y-L-V-K-L-I-H-I-P-L-N-Q-V-L-V-G-G-A"} +{"text": "### FUNCTION Plays an important role in the elongation step of protein synthesis ### SEQUENCE -M-K-H-L-A-A-Y-L-L-L-T-L-G-G-K-A-T-P-S-A-A-D-V-K-A-V-L-E-S-V-G-I-E-A-D-S-D-R-L-D-K-L-I-S-E-L-E-G-K-D-V-N-E-L-I-A-E-G-S-S-K-L-A-S-V-P-S-G-G-A-G-G-A-A-A-A-G-G-A-A-A-A-G-G-A-A-E-A-A-P-E-E-A-K-E-E-E-K-E-E-S-D-D-D-M-G-F-G-L-F-D"} +{"text": "### FUNCTION Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase The precise role of the epsilon subunit is unclear ### SEQUENCE -M-V-D-T-T-K-N-T-K-L-F-T-S-Y-G-V-K-T-S-K-A-I-T-T-E-V-A-A-K-L-I-S-K-A-K-R-P-L-F-V-V-G-T-G-V-L-D-P-E-L-L-D-R-A-V-K-I-A-K-A-K-N-I-P-I-A-A-T-G-S-S-M-P-G-F-V-D-K-D-V-N-A-K-Y-I-N-L-H-Q-L-G-F-Y-L-T-D-P-D-W-P-G-L-D-G-N-G-N-Y-D-T-I-I-L-L-G-H-K-K-Y-Y-I-N-Q-V-L-S-A-V-K-N-F-S-D-V-K-S-I-S-I-D-R-N-Y-I-Q-N-A-T-M-S-F-G-N-L-S-K-A-D-H-I-A-A-L-D-E-V-I-D-L-L"} +{"text": "### FUNCTION Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism ### SEQUENCE -M-G-S-F-L-S-F-F-L-I-S-S-R-T-L-A-L-V-L-I-S-V-T-G-E-T-L-E-S-N-F-L-H-H-K-K-E-K-L-T-H-F-R-V-Y-W-H-D-I-V-T-G-Q-D-S-S-S-V-S-I-M-N-P-P-K-K-Y-T-G-A-T-G-F-G-L-M-R-M-I-D-N-P-L-T-L-T-P-K-L-S-S-K-M-V-G-R-A-Q-G-F-Y-A-G-T-S-K-E-E-I-G-L-L-M-A-M-N-F-A-I-L-D-G-K-Y-N-G-S-T-I-T-V-L-G-R-N-S-V-F-D-K-V-R-E-M-P-V-I-G-G-S-G-L-F-R-F-A-R-G-Y-V-Q-A-S-T-H-E-F-N-L-K-T-G-N-A-I-V-E-Y-N-C-Y-L-L-H-Y"} +{"text": "### FUNCTION May be involved in free fatty acids export ### SEQUENCE -M-H-D-F-C-F-T-I-P-Y-G-I-L-L-I-V-G-G-F-I-G-Y-L-K-K-G-S-I-A-S-L-A-G-G-A-G-T-G-L-L-V-V-L-A-G-F-I-S-L-K-A-F-E-K-K-K-T-S-L-L-A-T-L-L-E-T-V-I-A-A-A-L-T-F-V-M-G-Q-R-F-L-Q-T-Q-K-I-M-P-A-A-L-V-A-G-I-S-A-L-M-T-C-F-Y-V-Y-K-I-A-T-G-G-N-H-I-P-P-K-A-E"} +{"text": "### FUNCTION May regulate negatively the cuticle development by interacting with the HD-ZIP IV transcription factor HDG1 ### SEQUENCE -M-A-D-I-T-E-Y-L-E-R-S-M-Q-N-C-S-L-I-D-R-R-S-S-M-G-D-G-F-G-M-S-D-E-H-I-P-I-S-D-R-F-L-E-L-S-S-H-F-S-V-P-S-H-L-E-Q-C-L-D-L-K-T-G-E-I-Y-Y-R-S-W-N-S-G-M-R-V-K-E-D-P-R-K-S-M-S-R-G-N-Y-A-D-Q-S-S-G-E-S-S-G-T-V-F-S-S-E-E-V-S-S-Y-Y-E-S-E-E-S-S-S-E-S-S-P-S-S-R-K-Y-H-K-E-E-Q-D-E-D-V-L-V-V-A-G-C-K-A-C-L-M-Y-F-M-V-P-K-L-F-K-D-C-P-K-C-A-T-Q-L-L-H-F-D-Q-L-H-S-T-S-P"} +{"text": "### FUNCTION May promote auxin-stimulated organ elongation, such as hypocotyls, stamen filaments and petals ### SEQUENCE -M-M-N-T-K-K-L-I-K-M-F-R-K-W-Q-Q-R-A-A-L-H-R-K-R-I-S-F-Q-R-P-S-T-R-S-T-T-V-E-K-G-C-F-V-V-Y-T-A-D-N-T-R-F-A-F-P-I-S-Y-L-S-N-S-V-F-Q-E-I-L-E-I-S-E-E-E-F-G-L-P-T-G-G-P-I-T-L-P-F-D-S-V-F-L-E-Y-L-I-K-L-I-K-R-R-M-D-G-D-T-E-K-A-L-L-M-S-I-S-S-A-R-C-S-L-Q-K-Q-E-Q-S-T-Q-Q-L-L-V-F"} +{"text": "### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-A-L-I-L-P-C-T-F-C-T-S-L-Q-K-K-N-F-P-I-N-R-R-Y-I-T-N-F-R-R-G-A-T-T-A-T-C-E-F-R-I-P-V-E-V-S-T-P-S-D-R-G-S-L-V-V-P-S-H-K-V-T-V-H-D-R-Q-R-G-V-V-H-E-F-E-V-P-E-D-Q-Y-I-L-H-S-A-E-S-Q-N-I-S-L-P-F-A-C-R-H-G-C-C-T-S-C-A-V-R-V-K-S-G-E-L-R-Q-P-Q-A-L-G-I-S-A-E-L-K-S-Q-G-Y-A-L-L-C-V-G-F-P-T-S-D-L-E-V-E-T-Q-D-E-D-E-V-Y-W-L-Q-F-G-R-Y-F-A-R-G-P-I-E-R-D-D-Y-A-L-E-L-A-M-G-D-E"} +{"text": "### FUNCTION Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism ### SEQUENCE -M-A-K-L-I-F-F-L-A-V-Q-I-L-F-L-A-V-V-S-S-A-G-D-G-E-D-F-A-R-T-M-D-R-K-L-L-G-L-H-K-K-E-K-L-T-H-F-K-V-Y-W-H-D-I-L-S-G-P-N-P-T-S-I-M-I-Q-P-P-V-T-N-S-S-Y-F-G-A-I-S-M-I-D-N-A-L-T-A-K-V-P-M-N-S-T-V-L-G-Q-A-Q-G-F-Y-A-G-A-A-Q-K-E-L-G-F-L-M-A-M-N-F-A-F-K-T-G-K-Y-N-G-S-T-I-T-I-L-G-R-N-T-A-L-S-E-V-R-E-M-P-I-V-G-G-S-G-L-F-R-F-A-R-G-Y-V-E-A-R-T-K-W-I-N-L-K-N-G-D-A-T-V-E-Y-S-C-Y-V-L-H-Y"} +{"text": "### FUNCTION Thionins are small plant proteins which are toxic to animal cells They seem to exert their toxic effect at the level of the cell membrane Their precise function is not known ### SEQUENCE -M-E-G-K-T-L-I-V-S-V-L-I-M-S-L-F-M-A-Q-N-Q-V-D-A-N-I-C-C-P-S-I-Q-A-R-T-F-Y-N-A-C-L-F-A-V-G-S-P-S-S-C-I-R-N-S-S-C-L-D-I-S-E-S-T-C-P-R-G-Y-T-N-D-I-L-E-N-T-G-D-A-V-T-E-Y-C-K-L-G-C-V-S-S-V-C-G-A-L-T-I-L-Q-N-S-D-A-S-E-I-V-N-G-E-V-E-K-C-T-M-A-C-S-T-V-C-T-K-G-S-M-N-A-V-E-N-A"} +{"text": "### FUNCTION Binds to both sense and antisense RNA ### SEQUENCE -M-P-H-G-T-L-E-V-V-L-V-S-A-K-G-L-E-D-A-D-F-L-N-N-M-D-P-Y-V-Q-L-T-C-R-T-Q-D-Q-K-S-N-V-A-E-G-M-G-T-T-P-E-W-N-E-T-F-I-F-T-V-S-E-G-T-T-E-L-K-A-K-I-F-D-K-D-V-G-T-E-D-D-A-V-G-E-A-T-I-P-L-E-P-V-F-V-E-G-S-I-P-P-T-A-Y-N-V-V-K-D-E-E-Y-K-G-E-I-W-V-A-L-S-F-K-P-S-E-N-R-S-R-G-M-D-E-E-S-Y-G-G-W-K-N-S-E-A-S-Y"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-S-K-N-V-S-R-N-C-L-G-S-M-E-D-I-K-K-V-F-Q-R-F-D-K-N-N-D-G-K-I-S-I-D-E-L-K-D-V-I-G-A-L-S-P-N-A-S-Q-E-E-T-K-A-M-M-K-E-F-D-L-D-G-N-G-F-I-D-L-D-E-F-V-A-L-F-Q-I-S-D-Q-S-S-N-N-S-A-I-R-D-L-K-E-A-F-D-L-Y-D-L-D-R-N-G-R-I-S-A-N-E-L-H-S-V-M-K-N-L-G-E-K-C-S-I-Q-D-C-Q-R-M-I-N-K-V-D-S-D-G-D-G-C-V-D-F-E-E-F-K-K-M-M-M-I-N-G-S-A"} +{"text": "### FUNCTION Probable lipid transfer protein ### SEQUENCE -M-A-S-S-T-L-L-I-T-L-L-I-S-L-S-A-F-F-L-R-M-V-L-A-Q-V-P-A-T-C-A-S-R-L-L-S-L-A-P-C-G-P-F-V-Q-G-F-A-Q-L-P-A-Q-P-C-C-D-S-L-N-Q-I-Y-S-Q-E-A-T-C-L-C-L-F-L-N-N-T-S-T-L-S-P-A-F-P-I-N-Q-T-L-A-L-Q-L-P-P-L-C-N-I-P-A-N-S-S-T-C-S-S-S-F-P-G-E-A-P-S-D-S-S-S-V-A-P-P-P-S-S-S-T-G-S-Q-I-S-Q-G-A-K-N-N-S-R-V-A-A-T-P-V-A-Q-M-A-P-R-P-T-S-F-M-G-L-G-Y-G-L-K-S-S-G-S-K-S-E-I-Q-L-T-I-F-A-L-A-A-I-L-P-A-A-L-L-L-I"} +{"text": "### FUNCTION May be involved in the regulation of ethylene receptor signaling Promotes cell expansion and plant growth ### SEQUENCE -M-A-K-V-G-K-L-T-K-L-K-S-A-M-K-K-W-P-S-F-A-K-N-H-H-H-S-T-S-S-A-A-V-S-D-E-L-S-E-D-N-N-L-H-V-V-Y-V-G-Q-T-R-R-P-Y-M-L-R-P-D-I-I-S-H-P-L-F-Q-E-L-V-D-R-S-S-S-R-S-I-E-Q-D-R-E-I-V-V-A-C-E-V-V-L-F-E-H-L-L-W-M-L-K-S-G-Q-E-G-G-S-V-E-E-L-A-E-F-Y-T-Y"} +{"text": "### FUNCTION Probably acts as a transcriptional activator Binds to the GCC-box pathogenesis-related promoter element May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways ### SEQUENCE -M-A-G-L-R-N-S-G-N-S-D-K-A-Q-N-D-G-K-G-V-P-S-A-Y-R-G-V-R-K-R-K-W-G-K-W-V-S-E-I-R-E-P-G-T-K-N-R-I-W-L-G-S-F-E-T-P-E-M-A-A-T-A-Y-D-V-A-A-F-H-F-R-G-R-E-A-R-L-N-F-P-E-L-A-S-S-L-P-R-P-A-D-S-S-S-D-S-I-R-M-A-V-H-E-A-T-L-C-R-T-T-E-G-T-E-S-A-M-Q-V-D-S-S-S-S-S-N-V-A-P-T-M-V-R-L-S-P-R-E-I-Q-A-I-N-E-S-T-L-G-S-P-T-T-M-M-H-S-T-Y-D-P-M-E-F-A-N-D-V-E-M-N-A-W-E-T-Y-Q-S-D-F-L-W-D-P"} +{"text": "### FUNCTION Probably acts as a transcriptional activator Binds to the GCC-box pathogenesis-related promoter element May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways ### SEQUENCE -M-D-S-R-D-T-G-E-T-D-Q-S-K-Y-K-G-I-R-R-R-K-W-G-K-W-V-S-E-I-R-V-P-G-T-R-Q-R-L-W-L-G-S-F-S-T-A-E-G-A-A-V-A-H-D-V-A-F-Y-C-L-H-R-P-S-S-L-D-D-E-S-F-N-F-P-H-L-L-T-T-S-L-A-S-N-I-S-P-K-S-I-Q-K-A-A-S-D-A-G-M-A-V-D-A-G-F-H-G-A-V-S-G-S-G-G-C-E-E-R-S-S-M-A-N-M-E-E-E-D-K-L-S-I-S-V-Y-D-Y-L-E-D-D-L-V"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-A-N-T-N-L-E-S-T-N-K-S-T-T-P-S-T-D-M-E-L-K-K-V-F-D-K-F-D-A-N-G-D-G-K-I-S-V-S-E-L-G-N-V-F-K-S-M-G-T-S-Y-T-E-E-E-L-N-R-V-L-D-E-I-D-I-D-C-D-G-F-I-N-Q-E-E-F-A-T-I-C-R-S-S-S-S-A-V-E-I-R-E-A-F-D-L-Y-D-Q-N-K-N-G-L-I-S-S-S-E-I-H-K-V-L-N-R-L-G-M-T-C-S-V-E-D-C-V-R-M-I-G-H-V-D-T-D-G-D-G-N-V-N-F-E-E-F-Q-K-M-M-S-S-P-E-L-V-K-G-T-V-A-N-S"} +{"text": "### FUNCTION Ubiquitin-like modifier protein which binds to a number of as yet unidentified target proteins ### SEQUENCE -M-A-T-G-G-K-V-S-F-K-V-T-L-T-S-D-P-K-L-P-F-K-V-F-S-V-P-E-G-A-P-F-T-A-V-L-K-F-A-A-E-E-F-K-V-P-P-Q-T-S-A-I-I-T-N-D-G-I-G-I-N-P-Q-Q-S-A-G-N-V-F-L-K-H-G-S-E-L-R-L-I-P-R-D-R-V-G-A-V-F-V-M-D-P"} +{"text": "### FUNCTION May be involved in chloroplast development ### SEQUENCE -M-I-P-T-R-C-N-E-I-N-G-S-R-P-S-S-L-K-L-A-G-E-S-H-T-I-K-K-T-S-S-C-K-S-K-P-R-P-H-G-R-A-S-P-V-I-I-Y-A-H-S-P-K-V-I-H-T-R-A-E-D-F-M-A-L-V-Q-R-L-T-G-L-D-E-I-I-R-R-N-T-S-E-S-S-S-S-V-V-T-E-E-V-N-V-G-D-D-N-T-A-A-P-F-S-Q-D-R-T-Q-R-Q-K-L-T-D-M-P-L-F-T-P-S-S-M-T-L-F-G-S-P-T-Q-L-M-Y-M-S-P-N-R-T-D-S-F-R-P-L-V-F-K-S-E"} +{"text": "### FUNCTION May be a ribosome silencing factor involved in organelle biogenesis and required for germination ### SEQUENCE -M-L-T-T-L-R-S-R-C-S-S-L-L-L-N-Q-S-W-K-L-A-P-N-R-I-F-A-S-S-P-S-F-S-S-S-A-G-I-S-N-V-S-E-I-L-T-L-P-E-V-E-K-I-L-A-D-V-K-A-D-N-V-T-V-I-P-T-H-N-H-C-F-W-A-D-F-T-V-I-A-T-G-R-S-D-W-H-L-R-N-I-A-Q-A-L-V-Y-R-A-K-Q-K-Q-K-G-A-K-H-V-M-L-P-S-V-Q-G-Y-N-S-K-W-I-V-I-D-Y-G-K-F-V-V-H-A-L-D-E-K-A-R-G-Y-F-N-L-E-S-L-W-S-A-E-S-S-G-T-D-T-S-D-Q-D-L-Q-N-V-F-V-K-V-R-P-K-N-N-S-K-R-K-P-A-K-V-S-S"} +{"text": "### FUNCTION Probable heavy-metal-binding protein ### SEQUENCE -M-I-V-W-M-G-V-Y-D-Q-R-S-K-G-K-I-T-K-S-I-S-D-L-P-G-I-H-S-S-Y-M-D-L-K-E-G-T-L-V-V-M-G-D-V-D-P-V-E-L-V-R-N-L-R-K-K-W-G-K-A-K-L-T-L-Y-V-P-Y-D-A-L-K-E-A-K-I-A-E-A-K-Q-K-R-E-E-I-E-R-E-A-L-Y-R-Y-N-R-E-I-R-D-I-F-N-D-K-E-E-Q-G-C-V-I-C"} +{"text": "### FUNCTION Probable thiol-disulfide oxidoreductase that may be involved in the redox regulation of a number of cytosolic enzymes ### SEQUENCE -M-G-A-N-V-S-T-P-D-Q-R-F-Q-V-T-H-F-R-S-T-K-P-W-T-P-R-P-E-I-Y-P-F-K-V-N-S-P-C-I-V-E-I-K-N-M-N-Q-W-K-S-R-L-N-A-L-K-D-T-N-K-L-L-V-I-E-F-T-A-K-W-C-G-P-C-K-T-L-E-P-K-L-E-E-L-A-A-K-Y-T-D-V-E-F-V-K-I-D-V-D-V-L-M-S-V-W-M-E-F-N-L-S-T-L-P-A-I-V-F-M-K-R-G-R-E-V-D-M-V-V-G-V-K-V-D-E-L-E-R-K-L-N-K-Y-T-Q-S-F-F"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-A-E-L-D-R-K-E-L-A-D-L-V-R-R-L-S-V-V-Q-G-C-V-T-L-S-S-G-K-Q-A-D-H-Y-V-D-L-R-R-A-T-L-H-H-R-A-S-A-L-I-G-R-L-M-R-E-L-T-K-D-W-N-Y-T-V-V-G-G-L-T-L-G-A-D-P-V-A-I-A-I-I-H-S-P-G-R-P-I-D-A-F-V-V-R-K-Y-A-K-T-H-G-L-Q-R-L-I-E-G-S-E-V-S-G-Q-R-V-L-V-V-E-D-T-S-T-T-G-A-S-A-L-T-A-V-R-A-V-Q-D-A-G-G-D-V-V-G-V-A-T-V-V-D-R-G-T-G-A-A-E-A-I-K-A-E-G-L-L-Y-R-S-V-L-G-L-A-D-L-G-L-G"} +{"text": "### FUNCTION Might mediate adherence to host cells by binding sulfated glycoconjugates ### SEQUENCE -M-A-E-N-P-N-V-D-D-L-R-A-P-L-L-A-A-L-G-A-A-D-L-A-L-T-T-V-N-E-L-V-G-N-M-R-E-R-A-E-E-T-R-I-D-T-R-S-R-V-E-E-S-R-A-R-V-A-K-L-Q-E-V-L-P-E-H-L-S-E-L-R-E-K-F-T-A-D-E-L-R-K-A-A-E-G-Y-L-E-A-A-T-N-R-Y-N-E-L-V-E-R-G-E-A-A-L-E-R-L-R-S-R-P-V-F-E-D-A-S-A-R-A-E-G-Y-V-D-Q-A-V-E-L-T-Q-E-A-L-G-T-V-A-S-Q-T-R-A-V-G-G-R-A-A-K-L-V-G-I-E-L-P-K-K-A-A-A-P-A-R-K-A-P-A-K-K-A-P-A-K-K-A-P-A-K-K-V-T-Q-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-I-A-P-I-R-I-V-G-D-P-V-L-H-T-P-T-A-P-V-Q-V-A-A-D-G-S-L-P-A-N-L-N-G-L-I-S-T-M-Y-D-T-M-D-A-A-H-G-V-G-L-A-A-N-Q-I-G-Y-G-L-R-V-F-V-Y-D-C-A-E-D-C-R-Q-T-A-R-R-R-G-V-V-I-N-P-I-L-E-T-S-E-I-P-E-T-M-P-D-P-D-T-D-N-E-G-C-L-S-V-P-G-E-S-F-P-I-G-R-A-Q-W-A-R-V-T-G-L-D-A-D-G-N-P-V-T-T-E-G-T-G-L-F-A-R-M-L-Q-H-E-T-G-H-L-D-G-F-L-Y-L-D-Y-L-I-G-R-H-A-R-S-A-K-R-A-I-K-S-R-H-W-G-V-P-G-L-S-W-M-P-G-E-V-P-D-P-F-G-P"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-T-K-K-K-V-A-G-L-I-K-L-Q-I-Q-A-G-Q-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-Y-N-A-A-T-E-N-Q-R-G-Q-V-I-P-V-E-I-T-V-Y-E-D-R-S-F-T-F-A-L-K-T-P-P-A-A-K-L-L-L-D-A-A-G-V-G-K-G-V-A-E-P-H-K-T-K-V-V-K-V-S-W-D-Q-V-R-E-I-A-E-T-K-K-A-D-L-N-A-N-D-I-D-A-A-A-K-I-I-A-G-T-A-R-S-M-G-I-T-V-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-R-A-D-K-A-T-A-V-A-N-I-A-E-Q-F-K-A-A-T-A-A-L-I-T-E-Y-R-G-L-T-V-A-N-L-A-E-L-R-R-S-L-T-G-S-A-S-Y-A-V-A-K-N-T-L-I-K-R-A-A-S-E-V-G-I-E-G-L-D-E-L-F-A-G-P-T-A-I-A-F-V-T-G-E-P-V-D-A-A-K-A-I-K-T-F-A-K-E-H-K-A-L-V-I-K-G-G-Y-M-D-G-H-P-M-T-V-A-E-V-E-R-I-A-D-L-E-S-R-E-V-L-L-A-K-L-A-G-A-M-K-G-T-F-A-K-A-I-G-L-F-N-A-P-T-S-Q-M-A-R-L-T-A-A-L-Q-E-K-K-A-F-E-P-A-S-A-E"} +{"text": "### FUNCTION Multidrug efflux pump Confers resistance to tetraphenylphosphonium ### SEQUENCE -M-A-Y-L-F-L-F-C-A-I-F-V-E-V-V-A-T-T-L-L-K-S-T-E-G-F-T-R-L-V-P-T-L-A-C-L-A-G-Y-A-V-T-F-T-L-L-A-L-S-I-S-R-G-M-K-T-D-V-A-Y-A-L-W-S-A-I-G-T-A-A-I-V-L-I-A-V-L-F-L-D-S-P-V-S-V-A-K-V-V-G-V-A-L-I-I-V-G-V-I-T-L-N-L-A-D-A-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-Q-A-H-N-L-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-Q-K-L-G-V-P-A-M-R-I-P-L-H-S-R-I-E-V-S-D-P-Y-V-L-V-L-P-T-Y-G-G-G-R-T-A-P-D-L-Q-A-G-G-Y-V-P-K-Q-V-I-A-F-L-N-N-E-Y-N-R-A-L-I-C-G-V-V-A-A-G-N-T-N-F-G-A-E-F-C-Y-A-G-D-V-V-A-R-K-C-G-V-P-Y-L-Y-R-F-E-L-M-G-T-E-D-D-V-T-A-V-R-A-G-L-A-N-L-W-K-E-H"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-A-T-Y-A-I-V-K-T-G-G-K-Q-Y-K-V-A-V-G-D-V-V-K-I-E-K-L-D-F-E-P-G-A-K-V-S-L-P-V-T-L-V-V-D-G-A-T-V-T-T-N-A-K-A-L-A-K-V-A-V-T-G-K-V-L-E-H-T-K-G-P-K-I-R-I-H-K-F-K-N-K-T-G-Y-H-K-R-Q-G-H-R-Q-Q-L-T-V-L-K-V-T-G-I-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-A-V-N-A-H-K-K-R-R-T-V-L-K-A-S-K-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-Q-L-H-S-L-G-Y-A-Y-R-D-R-R-A-R-K-G-E-F-R-K-L-W-I-S-R-I-N-A-A-A-R-A-N-D-I-T-Y-N-R-L-I-Q-G-L-K-A-A-D-V-D-V-D-R-K-N-L-A-D-I-A-I-S-D-P-A-A-F-T-A-L-V-E-V-A-R-S-G-L-P-E-D-V-N-V-P-S-G-E-A-A"} +{"text": "### FUNCTION Part of cytochrome c oxidase, its function is unknown ### SEQUENCE -M-H-I-E-A-R-L-F-E-F-V-A-V-F-F-V-I-M-A-V-L-Y-G-V-L-T-S-M-F-A-T-G-G-V-D-W-V-G-T-T-A-L-A-L-T-G-G-L-A-L-I-V-A-T-F-F-R-F-V-A-R-R-L-D-I-R-P-E-D-Y-E-G-A-E-I-S-D-G-A-G-E-L-G-F-F-S-P-H-S-W-W-P-V-L-V-A-L-S-G-S-V-A-A-V-G-I-A-L-W-L-P-W-L-I-V-A-G-V-V-F-V-L-A-S-A-A-G-L-V-F-E-Y-Y-V-G-P-E-K-H"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-S-I-P-Q-S-N-T-S-L-S-A-V-I-A-V-D-Q-F-D-P-S-S-G-G-Q-G-V-Y-D-T-P-L-G-I-T-N-P-P-I-D-E-L-L-D-R-V-S-S-K-Y-A-L-V-I-Y-A-A-K-R-A-R-Q-I-N-D-H-Y-N-Q-L-G-E-G-I-L-E-Y-V-G-P-L-V-E-P-G-L-Q-E-K-P-L-S-I-A-M-R-E-I-H-A-D-L-L-E-H-T-E-G-E"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-N-P-V-K-G-R-H-Q-A-R-K-R-A-V-D-L-L-F-E-A-E-A-R-D-L-S-P-L-E-I-I-E-V-R-S-A-L-A-K-S-K-L-D-V-A-P-L-H-P-Y-T-V-V-V-A-Q-G-V-S-E-H-T-A-R-I-D-E-L-I-I-S-H-L-Q-G-W-K-L-D-R-L-P-A-V-D-R-A-I-L-R-V-S-I-W-E-L-L-Y-A-D-D-V-P-E-P-V-A-V-D-E-A-V-E-L-A-K-E-L-S-T-D-D-S-P-G-F-V-N-G-L-L-G-K-V-M-L-V-T-P-Q-I-R-A-A-A-Q-A-V-Q-Q-A-V-R-M-A-A-G-T-S-E-D-H-V-P-Q-R-E-P-A-A-G-Q-L-G-Q-D-D-S-N-G-G-Q-V-A-A-V-C-R"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-T-T-A-D-F-K-N-G-L-V-L-V-I-D-G-Q-L-W-T-I-I-G-F-Q-H-V-K-P-G-K-G-P-A-F-V-R-T-K-L-K-N-V-L-S-G-K-V-V-D-K-T-Y-N-A-G-V-K-V-D-T-A-T-V-D-R-R-D-T-T-Y-L-Y-R-D-G-A-N-F-V-F-M-D-S-Q-D-Y-E-Q-H-P-L-P-E-S-L-V-G-D-T-A-R-F-L-L-E-G-M-S-V-Q-V-A-F-H-N-G-V-P-L-Y-V-E-L-P-V-T-V-E-L-E-V-T-H-T-E-P-G-L-Q-G-D-R-S-S-A-G-T-K-P-A-T-L-E-T-G-A-Q-I-N-V-P-L-F-I-N-T-G-D-K-L-K-V-D-S-R-D-G-S-Y-L-G-R-V-N-V"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-F-S-S-Q-H-R-L-L-Y-Q-P-S-G-P-D-L-S-K-N-L-D-P-E-R-G-R-R-L-G-I-D-V-G-S-V-R-I-G-V-A-F-S-D-P-D-G-I-L-A-T-P-V-E-T-V-R-R-Y-R-S-A-K-H-L-R-R-L-A-E-L-V-V-E-L-Q-V-V-E-V-V-V-G-L-P-W-T-L-T-D-R-T-G-S-S-A-K-D-A-I-D-T-A-E-A-L-A-R-R-V-A-P-V-P-V-R-L-V-D-E-R-L-T-T-V-S-A-Q-R-L-L-R-A-A-G-V-R-A-K-D-Q-R-A-V-I-D-Q-A-A-A-V-V-I-L-Q-N-W-L-D-Q-C-R-A-A-T-P-A-R-A-D-E-P-T-T-G-S-V-A-G-E-V-I-D-G"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-A-R-T-N-T-R-K-A-I-L-A-G-G-C-F-W-G-I-Q-N-L-F-R-R-Q-P-G-V-I-S-T-R-V-G-Y-T-G-G-G-T-P-N-A-T-Y-R-N-H-G-M-H-A-E-A-V-E-I-I-Y-D-P-A-I-T-D-Y-R-T-L-L-E-F-F-F-Q-I-H-D-P-T-T-R-N-R-Q-G-N-D-Q-G-T-S-Y-R-S-A-I-F-Y-L-D-D-E-Q-K-K-V-A-L-D-T-I-A-A-V-E-A-S-S-L-W-P-G-K-V-V-T-E-V-S-L-A-E-D-F-W-E-A-E-P-E-H-Q-D-Y-L-Q-H-Y-P-N-G-Y-T-C-H-F-V-R-P-N-W-K-L-P-R-R-A-P-A-D-A-K-A-D-S"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-A-E-P-T-L-A-S-G-W-Y-P-R-L-V-V-G-L-G-N-P-G-K-N-Y-G-R-T-R-H-N-V-G-F-M-V-A-N-L-L-A-V-R-L-G-S-K-F-E-V-H-K-R-S-G-A-D-V-V-N-G-R-L-A-G-C-S-M-L-V-A-K-P-R-N-Y-M-N-E-S-G-Q-Q-V-G-L-L-A-K-L-Y-S-V-T-P-A-D-I-I-I-V-H-D-D-L-D-L-D-F-G-R-I-R-L-K-L-G-G-G-E-G-G-H-N-G-L-R-S-V-A-A-A-L-G-T-K-D-F-Q-R-V-R-I-G-I-G-R-P-T-G-R-K-D-P-A-S-F-V-L-E-N-F-T-T-A-E-R-M-Q-V-P-T-I-C-K-R-A-A-D-A-T-E-L-L-V-G-L-G-L-E-P-A-Q-N-H-V-H-A-W"} +{"text": "### FUNCTION Interacts with the core proteasome alpha-subunit Interaction of Bpa with the proteasome stimulates proteasomal peptidase and casein degradation activity, which suggests Bpa could play a role in the removal of non-native or damaged proteins by influencing the conformation of the proteasome complex upon interaction ### SEQUENCE -M-N-N-D-N-D-D-S-I-E-I-I-G-G-V-D-P-R-T-M-A-T-R-G-E-D-E-S-R-D-S-D-E-P-S-L-T-D-L-V-E-Q-P-A-K-V-M-R-I-G-T-M-I-K-Q-L-L-E-E-V-R-A-A-P-L-D-E-A-S-R-N-Q-L-R-E-I-H-A-T-S-I-R-E-L-E-D-G-L-A-P-E-L-R-E-E-L-D-R-L-T-L-P-F-N-E-S-T-A-P-S-N-A-E-L-R-I-A-Q-A-Q-L-V-G-W-L-E-G-L-F-H-G-I-Q-T-A-L-F-A-Q-Q-M-A-A-R-A-Q-L-E-Q-M-R-H-S-A-L-P-P-G-M-G-K-P-G-Q-A-G-G-Q-G-T-G-Q-Y-L"} +{"text": "### FUNCTION Required for arabinosylation of arabinogalactan , an essential component of the mycobacterial cell wall Probably acts as an anchor protein recruiting AftA, the first arabinosyl transferase involved in AG biosynthesis ### SEQUENCE -M-L-R-F-I-V-T-G-S-L-A-T-A-V-D-F-S-V-Y-V-T-L-Y-R-G-G-G-L-Q-V-D-L-A-K-F-T-S-V-V-I-G-T-I-T-S-Y-M-I-N-R-R-W-T-F-Q-M-S-P-S-T-T-R-F-A-A-V-M-A-L-Y-G-I-T-F-A-V-Q-M-G-L-N-H-L-C-L-F-L-F-H-Y-Q-E-P-W-A-I-P-I-A-F-V-I-A-Q-G-L-A-T-V-I-N-F-I-V-Q-R-V-V-I-F-R-I-R"} +{"text": "### FUNCTION Involved in cell division ### SEQUENCE -M-P-K-S-K-V-R-K-K-N-D-F-T-I-T-S-V-S-R-T-P-V-K-V-K-V-G-P-S-S-V-W-F-V-T-L-F-V-G-L-M-L-I-G-L-V-W-L-M-V-F-Q-L-A-A-L-G-T-Q-A-P-T-A-L-H-W-M-A-Q-L-G-P-W-N-Y-A-I-A-F-A-F-M-I-T-G-L-L-L-T-M-R-W-H"} +{"text": "### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-A-H-C-D-F-V-T-N-S-L-I-Q-N-A-T-A-T-L-H-T-N-R-G-D-I-K-V-A-L-F-G-N-H-V-P-K-T-V-A-N-F-V-G-L-A-Q-G-T-K-E-Y-S-T-Q-N-A-S-G-G-P-S-G-P-F-Y-D-G-A-V-F-H-R-V-I-Q-G-F-M-I-Q-G-G-D-P-T-G-T-G-R-G-G-P-G-Y-K-F-A-D-E-F-H-P-E-L-Q-F-D-K-P-Y-L-L-A-M-A-N-A-G-P-G-T-N-G-S-Q-F-F-I-T-V-G-E-T-P-H-L-N-R-R-H-T-I-F-G-E-V-T-D-P-D-S-Q-K-V-V-D-A-I-S-T-T-A-T-D-G-N-D-R-P-T-E-P-V-V-I-D-S-I-T-I-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-N-R-A-P-K-R-E-V-L-A-D-P-M-Y-N-S-I-V-V-T-R-L-I-N-R-V-M-L-D-G-K-R-G-V-A-A-Q-I-V-Y-G-A-F-K-Q-I-E-E-A-T-G-N-N-P-L-E-V-F-E-T-A-M-E-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-S-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-T-I-A-R-N-R-G-E-H-T-M-Q-D-R-L-A-K-E-I-L-D-A-A-N-N-T-G-A-A-V-K-K-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-F-R-W"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-F-E-Y-L-N-G-K-L-V-K-I-S-P-T-N-I-V-I-D-V-A-G-I-G-Y-L-I-S-V-A-N-P-Y-A-W-S-A-L-M-N-T-E-V-K-I-Y-V-H-Q-V-I-R-E-D-A-H-S-L-Y-G-F-V-N-E-A-E-K-A-L-F-L-R-L-I-S-V-S-G-I-G-P-K-S-A-L-A-I-I-A-A-A-D-N-E-G-L-I-T-A-I-D-N-S-D-I-K-Y-L-T-K-F-P-G-V-G-K-K-T-A-M-Q-M-V-L-D-L-A-G-K-F-D-A-T-G-T-V-G-I-S-L-L-D-A-G-P-A-G-N-L-A-L-E-E-A-I-E-A-L-Q-A-L-G-Y-K-A-T-E-L-K-K-I-E-K-K-L-A-Q-E-T-G-L-T-S-E-E-Y-I-K-S-A-L-K-L-M-M-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-T-K-Y-E-I-L-Y-I-I-R-P-N-I-D-E-E-A-K-A-A-L-V-E-R-F-D-G-I-L-T-D-N-G-A-A-N-L-E-S-K-D-W-E-K-R-K-L-A-Y-E-I-N-D-F-R-E-G-I-Y-H-I-A-T-F-E-A-E-T-T-S-E-A-L-S-E-F-D-R-L-A-K-I-N-L-D-I-L-R-H-M-I-V-K-V-E-A"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-N-V-V-L-V-G-R-I-T-R-D-P-E-L-R-Y-T-P-Q-N-Q-A-V-A-T-F-S-L-A-V-N-R-Q-F-K-N-A-N-G-E-R-E-A-D-F-I-N-C-V-I-W-R-Q-Q-A-E-N-L-A-N-W-A-K-K-G-A-L-I-G-V-T-G-R-I-Q-T-R-N-Y-E-N-Q-Q-G-Q-R-V-Y-V-T-E-V-V-A-D-S-F-Q-M-L-E-S-R-S-A-R-E-G-M-G-G-G-T-S-A-G-S-Y-S-A-P-S-Q-S-T-N-N-T-P-R-P-Q-T-N-N-N-N-A-T-P-N-F-G-R-D-A-D-P-F-G-S-S-P-M-E-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Q-Q-R-R-G-G-F-K-R-R-K-K-V-D-F-I-A-A-N-K-I-E-V-V-D-Y-K-D-T-E-L-L-K-R-F-I-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-N-Q-R-K-V-V-N-A-I-K-R-A-R-V-M-A-L-L-P-F-V-A-E-D-Q-N"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-E-D-N-N-L-V-S-F-D-Q-G-W-F-V-I-Q-T-Y-A-G-Y-E-R-K-V-K-E-D-L-L-E-R-A-E-L-Y-N-M-A-D-K-I-L-R-V-E-I-P-T-E-T-I-R-T-E-V-N-G-K-M-K-E-V-E-E-N-L-F-P-G-Y-V-L-V-E-M-N-M-T-D-E-A-W-F-I-V-R-N-T-P-N-V-T-G-F-V-G-S-H-G-N-R-S-K-P-T-P-L-F-E-Q-E-I-Q-D-I-L-V-G-M-G-K-V-V-R-E-I-D-F-D-V-F-V-G-K-R-V-R-I-V-D-G-A-F-S-G-F-E-A-P-I-T-E-I-N-G-D-K-L-T-L-T-V-D-M-F-G-R-A-T-P-V-E-L-D-M-H-Q-I-E-D-I-Q-A"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-K-N-F-I-L-R-G-N-V-L-D-L-A-V-G-V-I-I-G-A-A-F-T-A-L-V-K-S-L-V-D-N-L-I-N-P-L-I-G-M-F-V-Q-S-T-A-L-A-H-L-S-V-T-V-G-K-T-K-F-T-Y-G-A-F-L-N-D-V-I-N-F-I-I-T-A-F-V-I-F-I-L-I-K-F-I-N-K-L-F-P-K-K-E-E-T-V-E-E-Q-K-N-E-E-L-E-T-L-Q-E-I-R-D-L-L-K-K-Q"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-T-K-K-I-R-I-R-L-K-A-Y-E-H-R-I-L-D-A-A-A-E-K-I-V-E-T-A-K-R-T-N-A-E-V-S-G-P-I-P-L-P-T-D-R-S-V-Y-T-V-I-R-A-T-H-K-Y-K-D-S-R-E-Q-F-E-M-R-T-H-K-R-L-I-D-I-I-E-P-T-Q-K-T-V-D-S-L-M-K-L-D-L-P-S-G-V-N-I-E-I-K-L"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-V-D-E-H-L-M-K-K-V-E-A-Q-V-N-A-E-R-K-S-V-I-K-T-W-S-R-R-S-T-I-F-P-N-F-V-G-L-T-I-A-V-Y-D-G-R-K-H-V-P-V-Y-V-Q-E-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-A-A-D-D-K-K-T-R-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-E-I-T-S-A-K-A-T-A-K-T-V-R-V-S-P-R-K-T-R-L-V-I-D-L-I-R-G-K-R-V-A-D-A-I-A-I-L-K-F-T-P-T-K-A-A-V-E-V-E-N-V-L-N-S-A-I-A-N-A-E-N-N-F-G-L-E-K-A-N-L-V-V-S-E-T-F-I-N-E-G-P-T-M-K-R-F-R-P-R-A-K-G-S-A-S-P-I-N-K-R-T-A-H-I-T-V-V-V-A-E-K-E"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-H-R-R-E-F-R-G-K-M-R-G-Y-A-K-G-G-D-T-I-S-F-G-E-Y-G-L-Q-A-T-T-S-H-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-N-G-Q-V-W-I-K-I-F-P-H-K-S-Y-T-A-K-A-I-G-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-P-V-K-R-G-V-V-M-F-E-L-G-G-V-D-E-A-T-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-T-K-F-V-K-R-G-E-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-K-Q-R-K-V-Y-Q-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-K-R-N-H-P-V-Y-G-K-R-I-N-Y-S-K-K-Y-K-A-H-D-E-N-N-S-A-K-T-G-D-I-V-R-I-M-E-T-R-P-L-S-K-D-K-H-F-R-L-V-E-I-V-E-E-A-V-I-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-T-E-S-R-L-K-V-A-D-N-S-G-A-K-E-L-L-T-I-R-V-L-G-G-S-S-R-K-F-A-G-I-G-D-I-V-V-A-T-V-K-S-A-A-P-G-G-A-V-K-K-G-E-V-V-K-A-V-I-V-R-T-K-S-G-A-K-R-P-D-G-S-Y-I-K-F-D-E-N-A-A-V-L-I-R-D-D-K-T-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-G-Y-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-F-V-K-T-G-D-T-V-K-V-I-A-G-K-D-R-G-T-T-G-K-V-I-K-A-L-P-K-V-N-K-V-V-V-E-G-V-A-I-M-K-K-H-Q-K-P-N-S-E-N-P-S-G-A-I-L-E-I-E-A-P-I-H-V-S-N-V-Q-V-L-D-K-N-G-V-A-G-R-V-G-Y-K-V-V-D-D-K-K-V-R-F-N-K-K-S-G-E-I-L-D"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-N-R-L-K-E-K-Y-T-N-E-V-V-P-A-L-T-E-Q-F-N-Y-T-S-I-M-A-V-P-K-V-D-K-I-V-I-N-M-G-V-G-D-A-V-N-N-S-K-N-L-D-K-A-V-A-E-L-A-L-I-S-G-Q-K-P-L-I-T-K-A-K-K-S-V-A-A-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-R-M-F-E-F-L-D-K-L-V-T-V-S-L-P-R-V-R-D-F-H-G-V-S-N-K-A-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-N-Y-D-D-V-D-K-V-R-G-M-D-I-V-I-V-T-T-A-N-T-D-E-E-S-R-E-L-L-A-K-L-G-M-P-F-A-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-V-V-K-N-Q-R-P-A-K-F-S-T-Q-A-Y-T-R-C-E-R-C-G-R-P-H-S-V-Y-R-K-F-K-L-C-R-I-C-L-R-E-L-A-Y-K-G-Q-L-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-F-L-T-R-I-R-N-G-N-M-R-K-F-D-V-V-E-A-P-A-S-K-I-K-R-Q-I-A-E-I-L-K-A-E-G-Y-V-K-D-V-E-Y-V-E-D-N-K-Q-G-V-I-R-V-F-L-K-Y-G-K-N-G-E-K-V-I-T-N-L-K-R-I-S-K-P-G-L-R-V-Y-V-K-S-D-D-I-P-K-V-L-N-G-L-G-T-A-I-I-S-T-S-T-G-V-V-T-D-K-V-A-R-E-T-N-V-G-G-E-V-I-A-Y-I-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-V-I-V-I-P-A-G-V-S-V-E-V-N-G-A-T-V-T-V-K-G-P-K-G-E-L-V-R-S-F-N-E-N-I-T-L-D-I-A-E-N-E-I-T-V-K-R-P-N-D-T-K-E-M-K-M-L-H-G-T-T-R-A-L-L-A-N-M-V-E-G-V-S-T-G-F-S-K-A-L-E-M-I-G-V-G-Y-R-A-Q-L-Q-G-T-K-L-V-L-S-V-G-K-S-H-Q-D-E-V-E-A-P-E-N-I-K-F-V-V-A-T-P-T-S-I-V-V-E-G-I-S-K-E-A-V-G-Q-T-A-A-Y-I-R-S-R-R-S-P-E-P-Y-K-G-K-G-I-R-Y-V-G-E-Y-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-L-R-Q-K-R-H-T-R-V-R-G-K-I-S-G-T-S-E-T-P-R-L-N-V-F-R-S-N-T-N-I-Y-A-Q-V-I-D-D-V-T-G-T-T-L-A-S-A-S-S-L-K-L-T-G-T-K-T-E-Q-A-A-E-V-G-K-L-V-A-E-A-A-K-A-K-G-V-E-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-A-A-L-A-T-A-A-R-E-A-G-L-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-E-N-R-R-N-D-R-E-Q-S-E-F-E-E-R-V-V-S-I-N-R-V-T-K-V-V-K-G-G-R-R-L-R-F-A-A-L-V-V-V-G-D-R-N-G-R-V-G-F-G-T-G-K-A-Q-E-V-P-E-A-I-R-K-A-I-E-A-A-K-K-N-L-I-T-V-P-M-V-G-T-T-L-P-H-E-A-L-G-V-F-G-G-G-K-I-L-L-K-P-A-V-E-G-A-G-V-A-A-G-G-A-V-R-A-V-L-E-L-A-G-V-A-D-V-T-S-K-S-L-G-S-N-T-P-I-N-V-V-R-A-T-V-D-G-L-N-Q-L-K-R-A-E-E-V-A-A-L-R-G-K-S-V-S-D-F-A"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-I-T-R-K-R-R-V-K-K-N-I-E-S-G-I-V-H-I-Q-S-T-F-N-N-T-I-V-M-I-T-D-V-H-G-N-A-L-A-W-S-S-A-G-A-L-G-F-K-G-S-K-K-S-T-P-F-A-A-Q-M-A-S-E-A-A-A-K-A-A-Q-E-Q-G-L-K-T-V-S-V-T-V-K-G-P-G-S-G-R-E-S-A-I-R-A-L-A-A-A-G-L-N-V-T-S-I-S-D-V-T-P-V-P-H-N-G-A-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-R-D-K-R-L-E-I-I-K-E-I-V-T-N-N-K-I-S-T-Q-E-E-L-Q-S-L-L-L-E-R-G-V-E-V-T-Q-A-T-L-S-R-D-I-R-K-L-N-I-I-K-K-R-D-K-G-E-S-F-Y-S-F-L-T-S-G-N-S-K-I-N-S-D-L-Q-L-Y-F-Y-N-F-V-I-S-A-K-S-V-G-A-L-V-V-I-R-T-K-L-G-E-A-D-V-L-A-N-A-L-D-D-E-R-D-S-R-T-D-I-L-G-T-I-A-G-A-D-T-L-L-V-I-C-A-S-E-K-A-A-N-I-L-T-A-E-I-K-Y-I-L-L-G"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-N-E-I-V-T-T-A-Q-D-R-M-K-Q-S-L-G-S-L-Q-R-D-L-G-H-I-R-A-G-R-A-N-A-S-L-L-D-R-V-Q-V-V-Y-Y-G-A-P-T-P-L-N-Q-L-A-S-I-T-I-P-E-A-R-V-L-M-V-T-P-F-D-K-S-I-L-K-D-I-E-K-A-L-Y-E-S-D-L-G-I-T-P-A-N-D-G-S-V-I-R-L-V-I-P-M-L-T-E-E-R-R-R-E-L-V-K-E-M-G-K-Y-I-E-S-A-K-V-A-I-R-N-I-R-R-D-A-M-D-T-A-K-K-S-E-K-A-K-E-I-T-E-D-D-L-K-D-L-E-N-N-I-Q-K-V-T-D-D-A-V-K-E-A-D-R-L-A-S-I-K-E-K-E-L-L-D-I"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-A-T-E-R-A-I-F-A-G-G-C-F-W-C-M-V-Q-P-F-E-E-R-E-G-I-L-S-V-I-S-G-Y-T-G-G-N-V-E-N-P-T-Y-E-Q-V-K-K-H-L-T-G-H-T-E-A-V-E-I-I-F-D-N-S-K-I-T-Y-Q-S-L-V-E-L-Y-W-T-L-T-D-P-T-D-A-F-G-Q-F-E-D-R-G-D-N-Y-R-P-V-I-F-V-E-N-E-E-Q-E-K-I-A-K-E-S-K-A-Q-L-Q-A-S-G-N-F-D-S-P-I-V-T-S-I-E-T-V-Q-K-F-W-P-A-E-D-Y-H-Q-G-F-Y-K-K-N-P-E-D-Y-A-Q-S-S-K-I-R-H-D-F-L-E-K-Q-W-K-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-Q-V-E-K-L-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-V-N-I-M-G-F-T-K-E-F-N-A-R-T-A-D-Q-A-G-M-I-I-P-V-V-I-S-V-Y-D-D-K-S-F-T-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-Q-K-G-S-G-E-P-N-K-T-K-V-A-S-V-T-K-A-Q-I-K-E-I-A-E-L-K-M-P-D-L-N-A-S-S-V-E-T-A-M-S-M-I-E-G-T-A-K-S-M-G-F-T-V-T-D"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-M-L-E-P-S-I-D-K-L-L-D-Q-V-D-S-K-Y-S-L-V-V-L-E-A-K-R-A-H-E-L-R-D-K-E-R-P-T-K-E-F-K-A-V-K-N-T-L-R-A-L-E-E-I-A-D-G-T-V-K-I-H-P-S-P-E-L-K-R-E-T-L-V-E-K-R-E-L-E-R-L-Q-A-K-M-K-E-Q-L-I-K-E-Q-I-A-K-E-E-A-E-E-E-A-K-Q-K-N-S-R-A-A-K-A-A-A-A-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-Q-E-I-I-A-Q-Y-A-R-K-E-G-D-T-G-S-P-E-V-Q-I-A-V-L-T-W-E-I-N-H-L-N-D-H-I-K-S-H-K-K-D-H-A-T-Q-R-G-L-M-K-K-I-G-H-R-R-N-L-L-G-Y-L-R-G-K-D-V-Q-R-Y-R-E-L-I-A-S-L-G-L-R-R"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-F-K-D-W-M-N-N-L-R-D-Y-F-V-E-D-D-E-E-F-N-E-P-A-R-P-V-Q-E-S-R-P-T-V-A-S-T-P-K-P-K-V-E-E-R-K-A-Q-P-E-Y-Q-T-R-R-P-A-Q-S-T-S-K-A-Q-T-Q-T-A-A-P-K-R-A-G-S-T-F-T-K-P-M-P-E-K-I-V-Q-Q-Q-T-V-S-Q-S-Q-S-V-A-A-T-V-S-T-I-A-I-K-E-P-R-A-Y-A-D-I-M-E-S-A-R-I-V-K-N-G-E-C-V-L-V-N-F-K-F-M-G-D-A-Q-A-R-R-S-I-D-F-M-T-G-V-V-F-T-L-D-G-D-I-Q-N-V-G-G-Q-I-F-L-M-T-P-A-N-I-T-V-D-A-A-K-E-M-S-I-L-A-G-Q-N-F-E-S-Y-D-I-Y"} +{"text": "### FUNCTION Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 ### SEQUENCE -M-N-K-Q-Q-A-E-L-L-N-G-I-A-L-A-Y-I-G-D-A-I-Y-E-V-F-V-R-E-Y-L-L-D-K-G-L-T-K-P-A-M-L-Q-K-N-A-T-K-F-V-S-A-K-A-Q-A-K-I-I-S-A-M-D-E-V-D-F-L-T-E-Y-E-L-T-Y-F-K-R-G-R-N-A-H-S-K-T-T-A-K-N-T-D-V-V-T-Y-R-I-S-T-G-F-E-A-V-V-G-I-L-H-L-T-Q-Q-K-E-R-L-Q-E-F-W-D-F-S-L-K-T-I-E-A-D-L-V"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-R-R-R-T-N-I-A-K-Q-D-N-R-K-P-M-M-N-G-A-I-R-A-R-E-V-R-L-I-G-A-E-G-E-Q-L-G-V-T-P-T-S-E-A-L-M-Q-A-E-N-L-N-M-D-L-V-L-I-S-N-Q-E-P-P-V-A-K-I-M-D-Y-T-K-F-M-F-E-Q-K-K-K-Q-K-E-A-K-K-K-Q-A-V-V-S-V-K-E-V-R-L-S-P-V-I-D-Q-N-D-F-D-T-K-L-R-Q-A-I-K-F-L-E-K-G-D-K-V-K-V-S-I-R-F-K-G-R-M-I-T-H-Q-D-V-G-R-Q-V-M-D-K-F-A-Q-A-T-K-E-V-A-V-V-E-Q-R-A-K-M-D-G-R-Q-M-F-L-Q-L-A-P-I-K-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-G-S-V-A-T-R-K-R-R-K-R-I-L-K-L-A-K-G-Y-Y-G-A-K-H-K-L-F-K-T-A-K-E-Q-V-M-N-S-Y-Y-Y-A-F-R-D-R-R-Q-K-K-R-D-F-R-K-L-W-I-A-R-I-N-A-A-A-R-M-N-G-L-S-Y-S-K-L-M-H-G-L-K-L-A-D-I-E-V-N-R-K-M-L-A-D-I-A-I-A-D-A-A-A-F-T-A-L-A-E-E-A-K-K-A-L-A-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-T-K-V-N-S-Q-K-Y-S-K-A-L-L-E-V-A-Q-E-K-G-Q-L-E-A-I-L-S-E-V-S-E-M-I-Q-L-F-K-E-D-N-L-V-A-F-L-S-S-E-V-Y-S-F-S-A-K-S-E-L-I-D-T-L-L-Q-T-S-S-E-V-M-S-N-F-L-N-T-V-R-S-N-G-R-L-G-D-L-G-E-I-L-D-E-T-K-N-A-A-D-D-M-F-K-I-A-D-V-G-V-V-S-S-I-A-L-T-N-A-Q-I-E-K-F-T-A-M-A-K-A-K-F-D-L-N-E-V-T-V-I-N-T-V-N-E-K-I-L-G-G-F-I-V-N-S-R-G-K-I-I-D-A-S-L-K-T-Q-L-A-K-I-A-A-E-I-L"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-A-E-L-N-K-V-A-N-E-R-N-A-Q-Q-K-S-A-M-R-T-L-I-K-K-F-E-A-A-P-T-E-E-L-Y-R-A-A-S-S-S-I-D-K-A-A-S-K-G-L-I-H-A-N-K-A-S-R-D-K-A-R-L-A-A-K-L-G"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-V-K-N-T-E-D-K-P-L-A-Q-N-K-K-A-R-H-D-Y-E-I-Y-E-T-F-E-A-G-I-V-L-T-G-T-E-I-K-S-V-R-Q-A-K-I-Q-L-K-D-G-F-A-R-V-R-N-G-E-V-W-L-S-N-V-H-I-A-P-F-E-Q-G-N-I-F-N-V-E-E-L-R-T-R-K-L-L-L-N-K-K-E-I-A-K-I-D-K-E-L-S-G-T-G-I-T-F-I-P-L-K-V-Y-L-K-N-G-F-A-K-V-L-M-G-L-A-R-G-K-K-D-Y-D-K-R-E-T-L-K-R-K-E-Q-N-R-D-I-A-R-Q-I-K-A-Y-N-R"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide ### SEQUENCE -M-A-R-K-E-I-I-D-E-I-T-M-K-R-A-I-T-R-I-T-Y-E-I-I-E-R-N-K-E-L-D-K-L-V-L-I-G-I-K-T-R-G-V-Y-L-A-K-R-I-Q-E-R-L-Q-Q-L-E-G-L-E-I-P-F-G-E-L-D-T-R-P-F-R-D-D-K-Q-A-Q-E-D-T-T-E-I-D-I-D-I-T-G-K-D-V-I-L-V-D-D-V-L-Y-T-G-R-T-I-R-A-A-I-D-G-I-V-K-L-G-R-P-A-R-V-Q-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-G-R-D-E-E-I-I-V-Q-M-S-E-H-D-G-N-D-S-I-L-I-K-R-E-D"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-K-F-Y-K-V-G-T-I-V-N-T-Q-G-L-Q-G-E-V-R-V-M-P-S-T-D-F-A-Q-E-R-F-S-K-G-S-V-L-A-L-F-D-D-K-D-N-Y-I-Q-D-L-K-V-K-S-G-R-P-Q-K-N-F-Y-V-V-K-F-E-G-F-Y-H-I-N-D-V-E-K-Y-K-G-Y-I-V-K-I-A-E-E-N-Q-E-D-L-D-D-G-E-F-Y-Y-H-E-I-I-G-S-D-V-Y-E-N-D-I-L-I-G-Q-I-S-E-I-L-Q-P-G-A-N-D-V-W-V-V-K-R-K-G-K-R-D-L-L-L-P-Y-I-P-P-V-I-L-N-V-D-V-N-Q-H-R-V-D-V-S-I-M-E-G-L-D-D"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-S-T-E-R-A-I-F-A-G-G-C-F-W-C-M-V-E-P-F-E-E-R-P-G-I-L-A-V-T-S-G-Y-T-G-G-H-I-E-Y-P-T-Y-D-Q-V-L-S-K-A-S-G-H-T-E-A-V-E-I-L-F-D-N-E-L-I-S-Y-D-E-L-L-D-I-Y-W-S-L-I-D-P-T-D-A-D-G-Q-I-Y-D-R-G-A-N-Y-R-P-V-I-F-V-E-S-E-E-Q-R-I-A-A-Q-K-S-K-I-A-L-E-K-S-G-I-W-D-K-P-I-V-V-P-I-E-E-A-K-T-F-W-P-A-E-E-Y-H-Q-Q-Y-Y-K-K-D-P-K-R-Y-Q-A-M-H-K-A-R-E-R-Y-L-A-L-Q-R-F-K-G-K-F-K-F-L-R-K-N-T-R"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-N-K-T-A-S-C-E-L-L-L-F-V-S-G-E-A-G-L-T-L-A-E-L-S-A-L-T-E-M-S-K-Q-A-C-Q-Q-Q-I-D-Y-L-K-E-K-Y-H-S-D-E-E-S-A-L-T-I-I-E-T-A-G-K-Y-R-M-A-T-K-E-E-F-A-E-I-L-K-N-Y-A-K-T-P-L-N-Q-S-L-S-K-S-A-L-E-V-L-S-I-I-A-Y-K-Q-P-L-T-R-L-E-I-D-H-L-R-G-V-N-S-S-G-V-L-S-T-L-R-A-F-D-L-V-E-K-V-G-Q-V-E-A-P-G-R-P-S-L-Y-A-T-T-D-F-F-L-D-Y-I-G-I-N-H-L-D-E-L-P-E-I-D-E-S-R-F-I-A-E-E-Q-T-L-F-N-E-S-E-E-N-E-N-Q"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-D-Y-K-V-N-E-A-T-I-A-K-K-A-E-L-V-D-V-Y-A-Q-K-M-T-E-A-A-S-I-V-V-A-D-S-R-G-L-S-V-D-Q-D-T-Q-L-R-K-Q-L-R-E-A-G-V-E-F-K-V-V-K-N-S-V-L-R-R-A-A-E-K-A-G-L-E-G-L-S-E-A-F-S-G-P-S-A-V-A-F-S-N-E-D-V-V-A-P-A-K-V-L-A-D-F-A-K-D-A-E-N-L-E-I-K-A-G-V-I-E-G-K-V-S-S-K-E-E-I-Q-A-I-A-S-L-P-S-R-D-G-L-L-S-M-L-L-S-V-L-Q-A-P-V-R-N-V-A-L-A-V-K-A-V-A-E-K-E-E-S-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-N-I-E-N-I-V-A-E-L-E-N-A-T-I-L-E-L-S-E-L-V-K-A-I-E-E-K-F-D-V-T-A-A-A-P-V-A-A-A-A-G-A-G-D-A-A-A-A-K-D-S-F-D-V-E-L-T-S-A-G-D-K-K-V-A-V-I-K-E-V-R-G-I-T-G-L-G-L-K-E-A-K-E-L-V-D-G-A-P-T-M-I-K-E-G-L-S-E-S-E-A-N-E-V-K-E-K-L-E-A-A-G-A-S-I-T-L-K"} +{"text": "### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-K-E-Q-I-F-D-I-I-E-T-V-S-G-T-D-E-F-R-E-D-L-D-M-D-L-F-E-E-G-I-L-D-S-M-R-A-I-M-L-I-V-E-L-E-G-A-F-D-I-S-L-P-P-S-E-M-D-R-E-D-W-N-T-A-N-K-I-A-A-R-V-Q-E-K-K-D-E-N"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-E-I-K-Q-H-A-L-A-G-T-L-E-S-S-D-V-Q-I-M-I-A-P-A-N-N-G-I-S-I-D-L-I-S-D-V-K-K-Q-F-G-K-Q-I-E-A-T-V-R-Q-V-L-A-A-Y-A-I-E-N-A-D-V-Q-V-I-D-K-G-A-L-D-L-V-I-K-A-R-A-I-A-V-V-E-R-A-I-E-A-K-D-L-N-W-E-V-L"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-T-I-N-T-N-N-L-T-I-T-I-S-A-A-S-K-K-Q-Y-P-E-N-D-W-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-L-L-N-R-K-N-F-A-R-T-S-G-Q-P-G-K-T-Q-L-L-N-F-Y-N-I-D-D-Q-L-H-F-V-D-V-P-G-Y-G-Y-A-R-V-S-K-K-E-R-E-K-W-G-K-M-I-E-E-Y-L-T-T-R-E-N-L-K-A-V-V-S-L-V-D-I-R-H-E-P-S-E-D-D-L-M-M-Y-E-F-L-K-Y-Y-H-I-P-V-I-L-V-A-T-K-A-D-K-V-P-R-G-K-W-N-K-H-E-S-I-I-K-K-A-M-K-F-D-S-T-D-D-F-I-I-F-S-S-T-D-K-T-G-F-E-E-A-W-E-A-I-L-R-Y-L"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-D-K-G-N-R-K-K-V-G-L-L-G-G-N-F-N-P-I-H-H-A-H-L-M-M-A-D-Q-V-A-Q-Q-M-N-L-D-K-V-L-L-M-P-E-N-I-P-P-H-V-D-E-K-E-T-I-S-A-K-H-R-V-K-M-L-E-L-A-I-K-E-N-P-R-L-G-L-E-L-I-E-I-E-R-G-G-K-S-Y-S-Y-D-T-L-K-L-L-T-E-A-N-P-D-T-D-Y-Y-F-I-I-G-S-D-M-V-E-Y-L-P-K-W-Y-K-I-D-E-L-L-K-L-V-T-F-I-A-L-R-R-K-D-T-I-S-K-S-P-Y-P-V-T-W-L-D-A-P-L-L-P-I-S-S-T-M-L-R-E-M-F-A-K-N-I-E-P-T-Y-F-L-P-Q-N-V-I-D-Y-I-K-T-E-K-L-Y-K-K-R"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-Y-V-E-L-V-D-E-T-G-Q-V-P-S-E-I-I-E-Q-T-K-E-V-L-A-F-A-A-K-K-L-N-L-K-E-S-T-E-M-S-V-T-F-V-D-N-A-R-S-H-E-L-N-L-Q-Y-R-E-T-D-R-P-T-D-V-I-S-L-E-Y-K-P-D-E-S-E-F-F-F-D-E-D-M-E-L-P-E-E-L-L-E-E-M-D-P-F-I-G-E-L-F-I-S-I-D-K-A-A-E-Q-A-A-D-Y-G-H-S-I-E-R-E-Y-G-W-L-A-V-H-G-F-L-H-I-N-G-Y-D-H-Y-T-P-E-E-E-S-E-M-F-G-L-Q-E-E-I-L-T-A-Y-G-L-T-R"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-N-Y-A-I-I-K-T-G-G-K-Q-L-K-V-E-E-G-S-V-I-Y-V-E-K-L-N-V-E-A-G-Q-T-V-T-F-D-E-V-I-F-V-G-G-E-T-T-K-V-G-A-P-L-V-E-G-A-T-V-V-G-E-V-E-K-H-G-K-Q-K-K-V-V-T-F-Q-Y-K-P-K-K-H-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-K-S-V-N-A"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-N-V-V-L-V-G-R-L-T-R-D-P-E-L-R-H-T-P-Q-N-Q-A-V-G-T-F-G-L-A-V-N-R-Q-F-K-N-A-N-G-E-R-E-A-D-F-I-N-C-V-I-W-R-Q-Q-A-E-N-L-A-K-F-A-K-K-G-A-L-I-G-I-T-G-R-I-Q-T-R-N-Y-E-N-Q-Q-G-Q-K-V-Y-V-T-E-V-V-A-D-T-F-Q-M-L-E-S-N-K-T-Q-G-Q-Q-T-S-K-P-Q-A-Q-N-K-K-P-Q-A-P-D-P-F-K-A-P-A-A-D-P-F-A-G-G-T-E-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-I-I-E-G-N-L-R-T-E-N-A-K-Y-G-I-V-V-A-Q-F-N-E-F-I-N-A-K-L-L-S-G-A-L-D-A-L-K-R-H-G-V-Q-E-E-E-I-D-I-A-W-V-P-G-A-F-E-I-P-I-I-A-Q-K-M-A-T-S-N-K-Y-E-A-I-I-C-L-G-T-V-I-R-G-S-T-S-H-Y-D-F-V-C-N-E-V-S-K-G-I-A-H-V-S-L-N-S-N-I-P-V-M-F-G-V-L-T-T-E-N-I-E-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-F-E-V-A-V-G-A-I-E-M-V-D-L-M-R-K-I-G"} +{"text": "### FUNCTION Electron transport system for the ribonucleotide reductase system NrdEF ### SEQUENCE -M-V-T-V-Y-S-K-N-N-C-M-Q-C-K-M-V-K-K-W-L-S-E-H-E-I-A-F-D-E-I-N-I-D-E-Q-P-E-F-V-E-K-V-I-E-M-G-F-R-A-A-P-V-I-T-K-D-D-F-A-F-S-G-F-R-P-S-E-L-A-K-L-A"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-L-A-Y-F-S-V-T-G-Q-T-R-R-F-V-S-K-T-N-L-P-N-V-E-I-S-P-D-D-D-I-E-M-N-E-P-F-L-L-I-T-P-S-Y-A-E-E-S-P-T-V-S-K-S-I-D-V-M-D-P-V-F-D-F-M-A-Y-N-D-N-Y-K-H-C-L-G-I-I-G-T-G-N-R-N-F-A-G-I-Y-I-F-T-A-K-E-L-S-A-K-Y-Q-I-P-L-L-Y-D-F-E-F-N-G-T-P-A-D-V-A-A-V-E-K-L-A-T-Q-L-D-K-G-A-K-V-T-F-K-N-P-L"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-F-K-K-Q-Q-K-L-V-A-Q-Y-Q-E-L-R-Q-E-L-K-K-E-K-N-Y-E-A-L-R-K-L-P-K-D-S-H-P-N-R-M-K-M-R-D-R-I-D-G-R-P-R-A-Y-M-R-K-F-G-M-S-R-V-N-F-R-K-L-A-H-E-G-K-I-P-G-V-K-K-S-S-W"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-L-I-E-S-I-N-A-A-Q-L-R-T-D-I-P-D-F-R-P-G-D-T-V-R-V-H-A-K-V-V-E-G-T-R-E-R-I-Q-M-F-E-G-V-V-I-A-R-K-N-S-G-I-N-E-T-Y-T-V-R-K-I-S-N-G-V-G-V-E-R-I-F-P-V-H-T-P-R-V-E-Q-I-E-V-I-R-H-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-T-G-K-K-A-R-I-A-E-R-R-R"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-T-K-K-E-D-V-K-F-E-D-N-L-A-E-L-E-N-I-V-R-K-L-E-S-G-D-V-A-L-E-D-A-I-A-E-F-Q-K-G-M-K-I-S-E-T-L-K-K-T-L-N-E-A-E-E-T-L-V-K-I-V-G-K-N-D-Q-E-S-D-F-S-P-E-Q-K-D-Y"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-V-F-G-T-G-V-D-N-V-E-L-S-R-I-Q-K-A-L-T-R-S-E-R-F-V-E-Q-V-L-T-A-V-E-L-E-K-Y-N-S-F-Q-S-T-A-R-K-T-E-F-L-A-G-R-W-A-A-K-E-A-F-S-K-A-Y-G-T-G-F-G-K-A-L-G-M-H-D-L-E-I-K-N-D-E-L-G-K-P-F-F-T-K-H-P-F-D-G-Q-V-H-L-S-I-S-H-S-N-L-E-A-V-A-F-V-V-L-E-K-N"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-V-F-E-K-V-Q-D-I-I-V-D-E-L-G-K-E-K-E-E-V-T-L-E-T-S-F-E-E-L-D-A-D-S-L-D-L-F-Q-I-I-N-D-I-E-D-E-F-D-V-E-V-D-T-E-A-D-M-K-T-V-A-D-L-V-K-Y-V-E-N-N-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-G-N-S-F-R-S-D-R-V-A-V-E-I-Q-R-E-I-N-D-I-L-R-N-K-V-R-D-P-R-V-Q-D-V-N-I-T-D-V-Q-L-T-G-D-L-S-Q-A-T-V-Y-Y-S-L-L-S-N-L-A-S-D-N-E-K-A-A-T-A-L-K-K-A-T-G-L-F-K-S-E-L-A-K-R-M-T-I-F-K-I-P-D-L-T-F-A-K-D-E-S-V-E-Y-G-S-K-I-D-E-L-L-R-G-L-N-N-K-S-E-Y"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-N-D-V-V-K-I-V-E-D-F-I-R-P-H-I-P-Q-P-F-E-L-F-A-V-E-W-E-K-F-G-G-D-M-M-L-S-I-L-V-D-K-E-G-G-I-E-I-D-E-T-A-E-L-S-E-I-I-S-P-L-L-D-T-I-S-P-D-P-F-P-T-E-G-Y-L-L-E-V-A-S-P-G-A-E-R-P-L-R-K-A-E-H-F-A-G-A-V-G-E-Y-I-F-V-K-L-Y-Q-K-I-N-N-E-K-E-I-T-G-D-L-V-S-F-D-G-E-T-L-V-V-D-V-L-D-K-T-R-H-K-N-I-E-I-P-L-S-A-V-A-K-A-Q-T-M-V-K-F"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-K-C-S-S-E-E-S-K-V-V-D-S-R-Q-A-E-D-A-I-R-R-R-R-V-C-E-S-C-G-F-R-F-T-T-F-E-R-I-E-E-M-P-L-L-V-I-K-K-D-D-K-R-E-P-F-N-R-E-K-I-V-R-G-L-V-R-S-A-Y-K-R-P-V-S-S-E-D-I-E-T-T-V-A-N-V-E-R-K-I-R-Q-L-D-S-N-E-V-E-S-D-V-I-G-E-F-V-M-Q-E-L-A-E-L-D-D-I-T-Y-I-R-F-A-S-V-Y-R-S-F-K-D-V-S-E-L-E-E-L-L-K-N-I-T-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-V-F-L-E-D-V-K-G-Q-G-K-K-G-Q-I-K-E-V-P-T-G-Y-A-Q-N-F-L-I-K-K-N-L-A-K-V-A-T-A-A-A-L-S-E-V-K-G-Q-A-K-A-K-E-K-E-E-A-E-L-L-A-E-A-K-A-L-K-E-V-L-E-K-E-D-T-V-V-E-I-K-M-K-V-G-Q-T-G-H-T-F-G-A-V-D-K-A-D-I-A-K-A-L-K-S-Q-F-N-L-K-L-D-K-R-K-I-Q-L-I-N-K-I-Q-A-L-G-T-K-D-V-P-V-K-L-H-R-D-V-T-A-V-V-K-V-K-I-S-E-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-F-Q-I-E-L-D-E-E-P-V-A-P-K-V-L-E-F-F-K-N-L-P-E-N-A-T-A-E-Q-S-L-E-T-F-Q-K-T-F-S-F-L-H-E-N-V-L-E-K-Y-T-S-D-L-F-T-P-S-T-L-K-E-E-L-D-E-Q-L-A-Q-A-E-N-N-A-Q-S-Q-L-S-E-L-L-K-N-T-K-R-F-V-L-N-Y-D-N-D-R-P-E-D-L-E-A-P-E-Y-F-T-Q-L-V-D-G-V-L-D-K-K-E-D-L-E-A-N-I-S-K-Y-L-T-K-T-W-S-F-S-R-L-T-L-V-E-Q-A-I-L-Q-V-S-S-Y-E-I-L-Y-T-E-T-P-D-V-V-A-V-N-E-A-V-E-L-S-K-D-F-S-D-E-K-S-S-R-F-I-N-G-V-L-T-N-F-L-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-L-A-K-D-L-K-S-G-M-T-F-L-N-G-E-K-L-L-R-V-M-E-A-S-H-H-K-P-G-K-G-N-T-I-M-R-M-K-L-K-D-V-R-S-G-S-T-F-D-D-T-Y-R-P-E-D-K-F-E-Q-A-V-I-E-T-V-T-A-Q-Y-L-Y-S-M-D-G-I-A-N-F-M-N-N-E-T-Y-E-Q-Y-E-I-P-V-E-Q-V-K-D-E-L-L-Y-V-L-E-N-T-D-V-K-I-Q-F-Y-G-T-E-V-I-G-I-Q-L-P-T-T-V-V-L-E-V-T-E-T-Q-P-S-I-K-G-A-T-V-T-G-S-G-K-P-A-T-M-E-T-G-L-V-V-N-V-P-D-F-V-E-A-G-T-K-L-E-I-N-T-Q-T-G-E-Y-L-K-R-A"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-G-Y-L-V-P-T-V-I-E-Q-S-S-R-G-E-R-A-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-T-G-P-V-E-D-G-M-A-N-S-I-I-A-Q-L-L-F-L-D-A-Q-D-N-T-K-D-I-Y-L-Y-V-N-T-P-G-G-S-V-S-A-G-L-A-I-V-D-T-M-N-F-I-K-S-D-V-Q-T-I-V-M-G-M-A-A-S-M-G-T-I-I-A-S-S-G-T-K-G-K-R-F-M-L-P-N-A-E-Y-L-I-H-Q-P-M-G-G-T-G-Q-G-T-Q-Q-T-D-M-A-I-V-A-E-Q-L-L-K-T-R-K-R-L-E-Q-I-L-A-D-N-S-N-R-S-L-E-Q-I-H-K-D-A-E-R-D-H-W-M-D-A-K-E-T-L-E-Y-G-F-I-D-E-I-M-E-N-N-S-L-K"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-E-K-T-F-P-M-T-Q-E-G-L-D-K-L-K-L-E-L-E-N-L-K-L-V-K-R-P-E-V-I-D-R-I-K-V-A-R-S-Y-G-D-L-S-E-N-S-E-Y-E-A-A-K-D-E-Q-A-F-I-E-G-R-I-S-T-V-E-T-M-I-R-Y-A-E-I-V-D-N-A-K-I-A-K-D-E-V-A-L-G-K-N-V-T-F-V-E-V-G-E-T-D-E-E-S-Y-Q-I-V-G-T-A-E-A-D-P-F-S-G-K-I-S-N-E-S-P-I-A-R-V-L-I-G-K-K-V-G-D-I-V-N-V-P-L-P-V-G-E-M-T-V-K-I-V-K-V-D"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-K-I-T-A-L-E-G-Q-K-I-S-E-L-S-M-I-E-V-A-H-A-L-L-E-Q-N-G-K-E-M-Q-F-S-E-I-I-R-A-I-Q-D-Y-L-E-K-S-D-D-E-I-K-A-S-I-S-R-F-Y-T-E-I-N-T-D-G-S-F-I-P-L-G-N-N-I-W-A-L-R-S-W-Y-A-I-D-E-I-D-E-E-V-I-A-L-D-E-I-E-D-E-E-E-E-K-P-A-K-K-R-K-K-V-N-A-F-G-I-E-D-E-I-D-P-E-D-E-E-G-T-K-E-T-T-E-E-D-M-S-Y-D-T-Q-A-E-D-E-D-K-D-D-V-A-A-Y-D-A-E-L-A-E-V-E-L-D-N-V-D-E-E-V-D-I-D-V-E-D-D-E-D-D-S-D-D-T-D-E-D"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-I-D-L-Y-L-S-P-S-C-T-S-C-R-K-A-R-A-W-L-Q-S-H-K-V-P-F-V-E-H-N-I-L-T-Q-P-M-T-T-N-D-L-R-H-I-L-T-K-T-E-N-G-T-E-D-I-I-S-T-R-S-K-V-F-Q-K-L-A-V-D-V-D-N-L-T-I-N-E-L-L-D-L-V-T-E-F-P-N-L-L-R-R-P-I-I-T-D-S-K-H-L-Q-I-G-F-N-E-D-E-I-R-A-F-L-P-R-E-Y-R-R-A-E-M-L-S-T-I-D"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-A-N-K-Q-D-L-I-A-E-V-A-A-K-T-G-L-T-K-K-D-S-E-K-A-V-N-A-F-G-E-V-V-T-E-F-L-A-K-G-E-K-V-Q-L-I-G-F-G-T-F-E-T-R-E-R-A-A-R-E-G-R-N-P-Q-T-G-E-A-I-K-I-A-A-T-V-V-P-A-F-K-A-G-K-A-L-K-D-A-V-K"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-A-D-K-Y-N-V-F-D-Q-L-G-E-L-E-N-T-L-N-T-T-L-T-Q-I-S-G-I-R-Q-V-L-E-S-S-M-T-E-N-A-T-L-R-M-E-L-E-K-L-R-D-R-L-A-E-F-E-K-K-E-V-K-K-E-T-P-K-D-Q-P-N-P-N-L-I-Q-I-F-N-E-G-F-H-V-C-H-L-H-Y-A-E-R-L-A-E-G-E-S-C-L-D-C-L-E-L-L-Y-R"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Y-Y-P-E-P-I-A-R-L-I-E-S-F-S-K-L-P-G-I-G-Q-K-T-A-T-R-L-A-F-Y-T-I-G-M-E-D-Q-D-V-N-E-F-A-K-N-L-L-S-A-K-R-D-L-S-F-C-S-I-C-G-N-L-T-E-S-D-P-C-A-I-C-T-D-P-T-R-D-R-T-T-I-L-V-V-E-E-S-K-D-V-L-A-M-E-K-I-R-E-Y-R-G-L-Y-H-V-L-H-G-T-I-S-P-M-N-G-I-S-P-D-E-I-N-V-K-T-L-I-T-R-L-M-D-S-E-V-K-E-V-I-I-A-T-N-A-T-S-D-G-E-A-T-A-M-Y-L-A-R-M-I-K-P-A-G-I-K-V-T-R-L-A-R-G-L-A-V-G-S-D-I-E-Y-A-D-E-I-T-L-S-K-A-V-E-N-R-L-E-I"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-F-K-V-F-Y-Q-K-D-N-T-R-S-P-R-R-E-T-T-E-A-L-Y-L-D-L-D-V-A-T-K-E-E-G-V-I-L-A-R-E-L-L-A-K-N-T-A-Y-H-V-E-F-I-D-S-L-S-D-E-S-V-E-Y-E-K-E-T-G-V-F-E-I-T-S-F"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-A-E-V-E-S-F-Q-L-D-H-T-K-V-L-A-P-Y-V-R-L-I-G-S-E-T-G-P-K-G-D-V-I-T-N-F-D-V-R-F-V-Q-P-N-A-N-A-I-G-M-A-A-L-H-T-I-E-H-S-M-A-S-L-I-R-D-R-I-D-G-M-I-D-F-S-P-F-G-C-Q-T-G-F-H-M-I-M-W-G-E-H-S-S-E-E-I-A-K-V-I-K-S-S-L-E-E-L-A-S-D-E-F-G-W-D-N-V-P-G-V-A-E-K-E-C-G-N-Y-R-N-H-S-L-F-G-A-K-E-W-S-K-K-I-L-S-E-G-I-S-T-D-P-Y-E-R-K-V-I"} +{"text": "### FUNCTION In complex with DhaQ, upon activation by dihydroxyacetone, activates transcription of the dhaKLM operon Binds the inverted repeat sequence 5'-GGACACATNATTTGTCC-3' located upstream of and partially overlapping with the -35 promoter sequence of the dhaKLM operon promoter ### SEQUENCE -M-S-A-F-F-L-N-M-K-K-S-I-I-T-Q-K-I-I-A-K-A-F-K-D-L-M-Q-S-N-A-Y-H-Q-I-S-V-S-D-I-M-Q-T-A-K-I-R-R-Q-T-F-Y-N-Y-F-Q-N-Q-E-E-L-L-S-W-I-F-E-N-D-F-A-E-L-I-N-D-N-S-D-Y-Y-G-W-Q-N-E-L-L-L-L-L-R-Y-L-D-E-N-Q-I-F-Y-Q-K-I-F-V-I-D-K-N-F-E-H-F-F-L-I-Q-W-E-N-L-L-D-K-V-I-F-D-Q-E-K-K-S-D-Y-H-W-S-D-L-E-K-S-F-I-C-R-Y-N-A-A-A-I-C-A-I-T-R-E-S-I-I-R-G-N-S-L-E-K-L-Y-S-Q-I-V-N-L-L-L-A-Q-I-K-I-F-E-S"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-I-R-G-F-E-V-V-T-K-Y-K-N-A-G-I-N-I-P-K-R-S-T-E-H-S-A-G-Y-D-I-E-A-A-E-T-V-S-F-A-P-G-E-I-K-L-I-P-T-G-L-K-A-Y-M-Q-A-G-E-V-L-Y-M-Y-D-R-S-S-N-P-R-K-K-G-L-V-L-I-N-S-V-G-V-I-D-K-D-Y-Y-N-N-P-D-N-E-G-H-M-F-M-Q-M-R-N-F-T-D-E-E-V-V-I-E-K-G-E-R-V-V-Q-G-V-F-M-P-F-L-V-A-D-G-D-E-N-Q-E-K-E-E-R-T-G-G-F-G-S-T-G-A"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-Q-I-T-E-E-Q-V-K-H-V-A-L-L-S-K-L-E-F-S-E-N-E-V-K-S-F-T-D-T-F-G-K-I-I-D-M-V-E-M-L-D-E-V-D-G-E-G-V-P-F-T-M-N-V-A-D-N-L-N-F-M-R-E-D-V-A-E-K-G-L-D-R-E-K-L-M-A-A-V-P-E-K-E-D-G-F-I-K-V-P-A-M-L-S-D-G-G-D-A"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-F-A-R-I-L-G-L-D-V-G-T-K-T-V-G-V-S-V-S-D-L-L-G-M-T-A-Q-P-V-E-T-I-K-I-D-S-E-A-G-E-L-G-F-E-R-L-G-V-L-I-K-E-Y-K-P-E-K-V-V-L-G-L-P-K-H-M-N-G-D-E-G-I-R-A-E-A-S-R-D-Y-G-T-K-L-A-N-E-F-G-L-E-V-A-Y-Q-D-E-R-L-T-T-A-Q-A-E-K-V-L-I-D-G-G-V-R-R-K-E-R-K-K-S-I-D-K-L-A-A-V-L-I-L-Q-N-Y-L-D-A-H-A-L-K-L"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-A-I-K-K-T-Y-R-V-K-R-S-K-D-F-D-Q-I-F-S-A-K-H-S-F-A-N-K-K-F-V-V-Y-K-L-N-T-N-Q-P-H-F-R-V-G-L-S-V-S-K-K-L-G-H-A-V-L-R-N-R-I-K-R-L-L-R-H-A-I-A-E-F-K-P-Y-L-T-D-E-D-F-V-I-I-A-R-S-G-V-E-T-L-S-F-E-E-V-K-K-N-L-K-H-V-L-K-L-S-K-I-Y-V-D-G-E-N-D"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-N-M-Q-S-M-M-K-Q-A-Q-K-L-Q-K-Q-M-Q-V-S-Q-E-E-I-A-N-T-T-F-V-G-K-S-A-Q-D-L-V-T-V-E-F-S-G-D-R-T-L-K-S-L-D-I-K-P-D-V-I-D-P-E-D-P-E-T-L-Q-D-M-V-T-D-A-V-N-D-A-L-S-Q-I-E-K-V-T-E-Q-K-L-G-K-F-T-K-G-L-P-F"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-K-M-I-V-G-L-G-N-P-G-D-K-Y-E-K-T-K-H-N-M-G-F-M-A-L-D-L-L-A-K-E-L-N-V-D-F-K-E-E-K-P-F-M-S-L-V-A-S-T-F-V-N-G-E-K-L-F-L-V-K-P-L-T-F-M-N-E-S-G-R-S-V-A-P-L-L-K-Y-Y-N-I-D-E-A-D-L-T-V-M-H-D-D-L-D-S-P-V-G-R-V-R-L-R-Q-K-G-S-S-G-G-Q-N-G-I-K-S-V-I-T-H-V-G-S-Q-T-F-N-R-V-K-I-G-I-G-R-P-K-H-G-M-T-V-G-N-H-V-L-S-G-F-D-N-E-D-K-E-I-A-Q-D-G-I-F-K-A-V-D-A-M-K-F-Y-L-E-N-G-D-F-Q-K-T-M-N-K-F-N"} +{"text": "### FUNCTION P-II indirectly controls the transcription of the glutamine synthetase gene ### SEQUENCE -M-K-K-I-E-A-I-I-K-P-F-K-L-D-D-V-R-E-S-L-S-D-V-G-I-T-G-M-T-V-T-E-V-R-G-F-G-R-Q-K-G-H-T-E-L-Y-R-G-A-E-Y-M-V-D-F-L-P-K-V-K-M-E-I-V-V-T-D-E-Q-V-D-Q-C-I-E-A-I-M-E-T-A-Q-T-G-K-I-G-D-G-K-I-F-V-Y-D-V-E-R-V-I-R-I-R-T-G-E-E-N-E-D-A-I"} +{"text": "### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-T-T-E-T-T-T-T-K-I-I-E-A-N-E-I-M-K-L-L-P-H-R-Y-P-F-L-L-V-D-R-V-V-D-Y-E-E-G-K-W-L-K-A-V-K-N-I-S-V-N-E-P-C-F-T-G-H-F-P-E-Q-P-I-F-P-G-V-L-I-L-E-A-M-A-Q-A-T-G-V-L-A-C-K-T-Y-R-Q-L-E-N-E-I-Y-Y-F-A-A-I-D-N-A-R-F-K-R-P-V-L-P-G-D-Q-M-V-L-E-V-H-F-L-K-E-R-R-G-I-T-R-F-T-G-V-A-T-V-D-G-Q-V-V-C-E-A-E-L-M-C-A-R-R-P-A"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-V-I-P-M-V-V-E-Q-T-A-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-E-R-V-I-F-L-G-G-E-V-E-D-R-M-A-N-L-I-V-A-Q-L-L-F-L-E-S-E-D-P-E-K-D-I-N-I-Y-I-N-S-P-G-G-S-V-T-A-G-M-A-I-Y-D-T-M-Q-F-V-K-P-D-I-R-T-L-C-V-G-Q-A-C-S-M-G-A-F-L-L-A-G-G-T-A-G-K-R-I-A-L-P-S-A-R-V-M-I-H-Q-P-L-G-G-F-R-G-Q-A-S-D-I-Q-I-H-A-Q-E-I-L-K-I-K-Q-T-L-N-E-R-L-A-F-H-T-G-Q-T-I-E-R-I-E-R-D-T-D-R-D-N-F-M-S-A-E-E-A-K-A-Y-G-L-V-D-E-V-L-A-S-R"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-Q-L-I-A-V-G-T-K-M-P-N-W-V-T-M-G-F-E-E-Y-Q-R-R-F-P-K-E-M-P-F-E-L-I-E-I-P-A-G-K-R-G-K-N-A-D-I-K-R-I-L-E-Q-E-G-K-A-M-L-A-A-C-G-K-S-R-I-V-T-L-D-I-P-G-K-P-W-T-T-E-Q-L-A-T-Q-L-E-V-W-K-N-D-G-R-D-L-S-L-L-I-G-G-P-E-G-L-S-A-E-C-K-A-A-A-E-Q-S-W-S-L-S-P-L-T-L-P-H-P-L-V-R-V-V-V-A-E-S-L-Y-R-A-W-S-V-T-M-N-H-P-Y-H-R-E"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-I-E-E-R-V-K-K-I-I-V-E-Q-L-G-V-K-E-D-E-V-K-P-E-A-S-F-V-E-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-I-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-S-A-I-D-Y-V-Q-N-N-Q"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-G-M-T-V-L-A-F-D-F-G-T-K-S-I-G-C-A-V-G-Q-S-I-T-G-T-A-Q-A-L-P-A-F-K-A-Q-D-G-I-P-N-W-D-A-I-G-K-C-L-A-E-W-Q-P-D-R-V-V-V-G-L-P-L-N-M-D-G-T-E-Q-D-L-T-V-R-A-R-K-F-A-H-R-L-H-G-R-F-G-V-A-V-E-L-Q-D-E-R-L-T-T-T-E-A-R-A-E-I-F-G-R-G-G-Y-K-A-L-N-K-S-K-V-D-G-I-S-A-C-L-I-L-E-S-W-F-E-N-Q-Q-V-K"} +{"text": "### FUNCTION A GTPase-activating protein that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-A-R-K-K-K-T-R-R-V-S-D-I-M-P-A-R-K-V-D-K-K-V-E-L-P-K-G-K-Q-G-K-K-L-T-R-Y-E-L-D-A-K-A-R-E-D-K-K-K-K-K-R-K-G-L-A-S-G-S-R-H-S-A-T-E-N-N-N-N-H-Q-A-L-A-K-K-D-P-R-L-G-S-R-K-K-V-P-L-I-V-E-F-V-N-K-P-E-K-G-M-T-I-P-P-M-K-V-E-E-K-V-A-K-L-D-P-M-L-E-L-E-Q-L-E-N-N-E-C-L-N-Q-L-L-D-A-L-D-A-G-K-T-L-S-A-E-D-Q-Q-F-V-D-D-C-L-D-R-I-A-Q-L-M-D-E-L-G-I-S-E-D-D-D-P-E-E-D-L-L-R-T-F-E-K-I-D-I-N-Q-F-R"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-I-S-K-H-C-K-E-A-G-N-H-R-M-S-S-P-A-L-N-Y-V-V-G-L-L-A-R-R-E-Y-S-E-F-E-L-R-C-K-M-Q-E-K-G-F-S-E-Q-E-I-D-D-T-L-A-F-C-Q-Q-K-N-W-Q-N-D-R-R-F-A-E-N-Y-L-T-F-R-A-Q-R-G-Y-G-F-A-R-I-K-Q-E-L-Q-Q-L-K-G-I-S-S-A-L-I-S-E-A-E-Q-T-L-A-P-D-W-Q-H-H-A-L-T-V-L-R-K-K-F-P-Q-Y-A-E-I-T-D-L-K-L-K-Q-K-V-W-R-Y-M-L-S-H-G-F-K-P-E-Q-F-A-H-Y-V-G-H-T-E-Y-E-E"} +{"text": "### FUNCTION Involved in the biogenesis of TorA Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor ### SEQUENCE -M-M-P-F-S-R-E-E-R-Q-F-V-Y-T-W-L-S-N-M-L-G-H-E-L-S-A-S-Q-L-A-Q-Y-Q-Q-G-L-F-D-D-F-F-A-F-L-T-E-Q-G-F-Q-A-Q-V-E-G-I-Q-Q-Q-L-Q-Q-L-K-T-V-E-L-A-H-L-E-L-A-A-D-Y-T-Q-L-F-L-L-D-G-S-S-S-A-L-P-Y-A-S-V-Y-L-P-E-A-Q-L-T-C-H-F-T-F-L-E-A-L-L-V-R-F-Q-L-Q-L-N-R-D-K-P-E-P-S-D-H-L-C-V-Y-L-E-L-L-R-Q-L-A-E-V-D-D-M-K-T-Y-R-Q-L-I-Q-D-A-L-L-P-W-L-L-P-F-N-D-K-V-Q-R-V-K-T-R-T-T-F-Y-Q-Q-V-V-V-L-L-I-L-L-L-Q-A-D-C-Q-N"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-T-E-T-T-T-K-K-R-W-Y-V-L-Q-A-F-S-G-F-E-G-R-V-A-T-T-L-R-E-Y-I-K-L-H-Q-M-E-D-Q-F-G-E-V-L-V-P-T-E-E-V-V-E-N-V-A-G-K-R-R-K-S-E-R-K-F-F-P-G-Y-V-L-V-Q-M-E-M-N-D-E-T-W-H-L-V-R-S-V-P-R-V-M-G-F-I-G-G-T-A-D-K-P-A-P-I-S-Q-R-E-A-D-R-I-L-N-R-L-Q-E-S-S-E-K-P-R-H-R-K-E-F-Q-P-G-E-E-V-R-V-T-E-G-P-F-A-D-F-N-G-T-V-E-E-V-D-Y-E-K-G-R-L-K-V-S-V-S-I-F-G-R-A-T-P-V-E-L-E-F-S-Q-V-E-K-T-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-Q-A-Y-V-K-L-Q-V-A-A-G-M-A-N-P-S-P-P-V-G-P-A-L-G-Q-Q-G-V-N-I-M-E-F-C-K-A-F-N-A-R-T-E-S-L-E-K-G-L-P-I-P-V-V-I-T-V-Y-A-D-R-S-F-T-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-I-K-S-G-S-G-K-P-N-K-D-K-V-G-K-V-T-L-E-Q-V-R-Q-I-A-E-T-K-A-A-D-M-T-G-S-S-I-E-T-K-M-K-S-I-A-G-T-A-R-S-M-G-L-V-V-E-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-Q-D-K-Q-A-I-V-A-E-V-N-E-A-A-K-G-A-L-S-A-V-I-A-D-S-R-G-V-T-V-D-K-M-T-E-L-R-K-V-A-R-E-N-G-V-S-M-R-V-V-R-N-T-L-L-R-R-A-V-E-G-T-E-F-E-C-L-K-D-T-F-V-G-P-T-L-I-A-F-S-T-E-H-P-G-A-A-A-R-L-F-K-D-F-A-K-A-N-D-K-F-E-I-K-G-A-A-F-E-G-K-I-Q-D-V-E-F-L-A-T-L-P-T-Y-D-E-A-I-A-R-L-M-G-T-M-K-E-A-A-A-G-K-L-V-R-T-L-A-A-L-R-D-K-L-Q-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-L-T-N-E-Q-I-I-E-A-I-A-S-K-S-V-T-E-I-V-E-L-I-A-A-M-E-E-K-F-G-V-S-A-A-A-A-A-V-A-V-A-A-G-P-A-E-A-A-E-E-K-T-E-F-D-V-V-L-A-G-A-G-A-N-K-V-A-V-I-K-A-V-R-G-A-T-G-L-G-L-K-E-A-K-D-L-V-E-S-A-P-A-V-L-K-E-G-I-S-K-A-E-A-E-A-L-K-K-E-L-E-E-A-G-A-Q-V-E-V-K"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-D-L-I-D-A-I-A-S-A-A-E-L-N-K-K-Q-A-K-A-A-L-E-A-T-L-E-A-I-S-G-S-L-K-A-G-E-P-V-Q-L-I-G-F-G-T-F-K-V-N-S-R-K-A-R-T-G-R-N-P-Q-T-G-A-E-I-K-I-A-A-S-K-V-P-A-F-V-A-G-K-A-L-K-D-A-V-K"} +{"text": "### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-S-S-K-S-I-E-L-P-V-L-G-Q-V-L-R-L-N-C-P-E-E-Q-H-E-A-L-K-Q-A-A-R-E-L-D-L-R-V-S-E-M-K-E-R-T-G-I-L-Q-L-E-R-V-L-S-I-V-A-L-N-L-S-Y-E-L-L-Q-A-Q-Q-K-T-T-S-I-E-A-L-L-Q-H-R-I-Q-Q-L-D-H-S-L-E-S-I-L-T-Q-K-V-N-N"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-I-S-I-T-Q-L-L-I-I-V-A-I-V-V-L-L-F-G-T-K-K-L-R-T-L-G-S-D-L-G-E-S-V-K-G-F-K-K-A-M-A-D-D-N-K-E-K-D-A-E-F-K-S-L-S-D-D-S-E-T-T-A-K-T-E-K-A-K-D-K-E-Q-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-T-L-A-N-I-K-S-A-K-K-R-A-I-Q-S-E-K-R-R-Q-H-N-A-S-Q-R-S-M-M-R-T-Y-I-K-K-V-Y-A-A-V-A-A-G-D-K-S-V-A-E-K-A-F-V-E-M-Q-K-V-V-D-R-M-A-S-K-G-L-I-H-A-N-K-A-A-N-H-K-A-N-L-S-A-Q-I-K-K-L-A"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-S-V-G-Q-Q-I-I-F-I-S-S-G-A-A-L-G-A-L-S-R-W-G-L-G-L-L-L-N-P-L-F-S-A-F-S-L-G-T-L-V-A-N-Y-L-G-C-L-I-I-G-V-F-L-A-F-F-W-Q-Y-P-Q-C-S-A-E-W-R-L-F-F-V-T-G-F-L-G-S-L-T-T-F-S-T-F-S-A-E-V-I-E-N-L-I-Q-Q-K-W-L-A-G-L-M-L-A-S-G-H-L-L-G-C-L-L-F-T-A-L-G-V-F-I-W-R-Y-W-Q"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-L-F-I-F-L-L-V-A-V-L-L-L-F-Q-Y-D-F-W-F-G-K-N-G-Y-L-D-Y-K-R-T-A-Q-Q-I-A-Q-H-K-Q-E-N-E-K-L-S-Q-R-N-Q-V-V-A-A-E-I-K-D-L-K-Q-G-V-E-A-I-E-E-R-A-R-F-Q-H-D-M-V-K-P-D-E-I-F-Y-H-I-V-K-E-Q-K"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-Q-K-I-M-I-S-D-A-A-Q-A-H-F-R-R-L-L-D-Q-Q-E-E-G-T-H-I-R-I-F-V-V-N-P-G-T-P-N-A-E-C-G-V-S-Y-C-P-P-N-A-V-E-A-T-D-T-E-M-Q-Y-A-S-F-S-A-F-V-D-E-I-S-L-P-F-L-D-E-A-E-I-D-Y-V-T-E-E-L-G-A-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-A-D-D-A-P-L-L-E-R-V-E-Y-V-I-Q-T-Q-I-N-P-Q-L-A-G-H-G-G-R-I-T-L-I-E-I-T-E-D-G-Y-A-I-L-Q-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-D-G-I-E-K-Q-L-L-S-L-F-P-G-E-L-Q-G-A-K-D-V-T-E-H-Q-R-G-E-H-S-Y-Y"} +{"text": "### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-N-E-I-R-V-T-Q-T-L-D-T-L-G-L-R-C-P-E-P-V-M-L-V-R-K-H-I-R-F-L-E-E-G-D-V-L-L-V-I-A-D-D-P-A-T-T-R-D-I-P-S-F-C-Q-F-M-E-H-T-L-L-K-S-E-I-E-H-I-P-F-Q-Y-W-V-K-K-G-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-V-F-N-L-T-V-V-S-A-E-Q-Q-I-F-S-G-Q-V-E-S-I-Q-A-T-G-I-E-G-E-L-G-I-L-A-G-H-T-P-L-L-T-A-I-K-P-G-I-V-K-L-T-L-E-D-G-K-E-E-V-I-Y-V-S-G-G-F-L-E-V-Q-P-N-V-V-T-V-L-A-D-T-A-I-R-G-D-E-L-D-G-D-R-I-L-A-A-K-K-R-A-E-E-N-I-R-T-R-H-G-D-A-N-Y-E-M-L-A-S-K-L-S-K-E-L-A-K-L-R-A-Y-E-L-T-E-K-L-V-K-N-K-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-E-L-T-T-I-A-R-P-Y-A-K-A-A-F-D-F-A-I-E-Q-N-A-V-E-K-W-A-N-M-L-H-F-S-S-E-L-I-K-D-E-T-M-Q-T-F-L-K-S-S-L-S-A-S-K-L-A-D-T-V-I-S-I-C-G-E-Q-L-D-Q-Y-G-Q-N-L-I-R-L-M-A-E-N-K-R-L-E-V-L-P-A-I-Y-Q-A-F-Q-H-Y-V-E-E-H-Q-K-V-A-E-V-Q-V-I-S-A-Q-P-L-N-A-T-Q-E-Q-K-I-A-S-A-M-E-K-R-L-A-R-K-V-K-L-N-C-S-L-D-S-S-L-I-A-G-V-I-I-R-T-D-D-F-V-I-D-G-S-S-R-G-Q-L-S-R-L-A-N-E-L-Q-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-L-N-A-T-L-I-G-Q-L-I-A-F-A-I-F-V-A-F-C-M-K-F-V-W-P-P-I-I-K-A-I-E-E-R-Q-R-S-I-A-N-A-L-A-S-A-E-A-A-R-K-E-Q-A-D-T-K-A-L-V-E-Q-E-I-T-E-A-K-M-Q-A-Q-Q-I-I-D-L-A-N-K-R-R-N-E-I-L-E-E-V-K-V-E-A-E-A-T-K-A-K-I-I-E-Q-G-Y-A-E-V-E-A-E-R-K-R-V-Q-E-E-L-R-V-K-V-A-S-L-A-I-A-G-A-E-K-I-V-G-R-T-V-D-E-A-A-N-S-D-I-I-D-K-L-V-A-E-L"} +{"text": "### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-L-E-I-L-D-Q-L-E-E-K-I-K-Q-A-V-E-T-I-Q-L-L-Q-L-E-I-D-E-L-K-E-K-N-N-Q-S-Q-Q-A-N-D-A-L-R-S-E-N-E-Q-L-K-S-E-H-Q-N-W-Q-E-R-L-R-S-L-L-G-K-I-D-N-V"} +{"text": "### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-D-S-N-K-I-T-F-F-T-R-F-E-Q-D-I-L-A-G-R-K-T-I-T-I-R-D-K-S-E-S-S-F-Q-P-N-Q-I-L-A-V-Y-T-N-E-T-D-R-F-F-A-N-I-K-V-L-S-V-T-P-I-H-F-E-A-L-S-E-A-H-A-Q-Q-E-N-M-T-L-P-E-L-R-Q-V-I-K-E-I-Y-P-Q-E-D-C-F-W-V-I-A-F-E-L-V-D"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-S-A-F-S-E-I-S-P-Q-Q-A-W-Q-L-V-Q-Q-H-A-A-A-L-L-D-I-R-N-E-T-H-F-A-L-A-H-P-A-Q-A-F-H-L-S-H-Q-S-Y-G-E-F-E-M-Q-Y-E-D-D-H-P-V-I-V-I-C-Y-H-G-V-S-S-R-G-A-A-M-Y-L-I-E-Q-G-Y-T-Q-V-Y-S-V-T-G-G-F-E-A-W-E-R-D-G-L-P-I-E-R-I-G"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-E-E-N-Q-V-N-A-A-D-T-Q-A-T-Q-Q-P-V-L-Q-I-Q-R-I-Y-V-K-D-V-S-F-E-A-P-N-L-P-H-I-F-Q-Q-D-W-E-P-K-L-S-F-D-L-S-T-E-A-K-Q-V-G-D-D-L-Y-E-V-C-L-N-I-S-V-E-T-T-M-E-S-S-G-D-V-A-F-I-C-E-V-K-Q-A-G-V-F-T-I-S-G-L-E-E-M-Q-M-A-H-C-L-T-S-Q-C-P-N-M-L-F-P-Y-A-R-E-L-V-S-S-L-V-N-R-G-T-F-P-A-L-N-L-S-P-V-N-F-D-A-L-F-M-D-Y-L-Q-R-Q-E-Q-A-E-Q-T-T-E-E-E-N-K-D-V-H"} +{"text": "### FUNCTION Catalyzes the decarboxylation of oxaloacetate coupled to Na translocation ### SEQUENCE -M-T-N-A-E-L-L-Q-E-G-I-N-L-M-F-A-G-V-G-F-V-M-L-F-L-F-I-L-I-Y-A-I-E-F-M-S-K-L-V-N-T-Y-F-P-E-P-V-K-A-P-S-T-K-P-I-Q-A-E-N-H-D-L-E-R-L-R-P-V-I-V-A-A-I-A-H-H-R-R-Q-Q-G-L-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA It is important during the early stages of 50S assembly It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-E-L-Q-V-V-G-A-N-A-L-T-V-S-E-T-T-F-G-R-E-F-N-E-A-L-I-H-Q-V-V-V-A-Y-A-A-G-A-R-Q-G-S-R-A-Q-K-T-R-A-E-V-S-G-S-G-K-K-P-W-R-Q-K-G-T-G-R-A-R-S-G-D-I-K-S-P-I-W-R-S-G-G-V-T-F-A-A-K-P-Q-D-H-S-Q-K-V-N-K-K-M-Y-R-G-A-I-K-S-I-L-S-E-L-V-R-Q-D-R-L-I-V-V-E-K-F-E-V-E-A-P-K-T-K-V-L-V-Q-K-L-K-E-L-A-L-E-D-V-L-I-I-T-A-S-L-D-E-N-L-F-L-A-A-R-N-L-Y-K-V-D-V-R-D-V-Q-G-I-D-P-V-S-L-I-A-F-D-K-V-V-V-T-V-D-A-V-K-Q-I-E-E-M-L-A"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-Q-Q-E-R-L-L-K-V-L-K-A-P-H-V-S-E-K-A-T-N-N-A-E-K-S-N-T-I-V-F-K-V-A-L-D-A-N-K-V-E-I-A-N-A-V-E-Q-L-F-E-V-K-V-D-S-V-R-T-V-V-V-K-G-K-T-K-R-H-G-A-R-M-G-R-R-S-D-W-K-K-A-Y-V-T-L-Q-E-G-Q-S-L-D-F-V-E-G-A-E"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-I-A-K-H-R-Y-A-R-T-S-A-Q-K-A-R-L-V-A-D-L-I-R-G-K-K-V-A-A-A-L-E-I-L-T-F-T-N-K-K-A-A-A-L-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-D-G-A-D-I-D-D-L-K-V-A-K-I-F-V-D-E-G-P-S-M-K-R-V-M-P-R-A-K-G-R-A-D-R-I-L-K-R-T-S-H-I-T-V-V-V-S-D-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-V-H-K-G-R-N-R-G-I-A-A-G-T-E-V-S-F-G-T-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-A-V-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-V-L-Y-E-M-D-G-V-S-E-E-I-A-R-N-A-F-A-L-A-A-A-K-L-P-I-K-T-T-F-V-T-K-T-V-M"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-T-D-K-I-R-S-V-Q-G-K-V-V-S-D-K-M-D-K-S-F-V-V-A-I-E-R-K-V-K-H-P-L-Y-G-K-F-I-R-R-T-T-K-L-H-V-H-D-E-N-N-E-A-K-L-G-D-I-V-E-I-K-E-C-R-P-L-S-K-T-K-S-W-T-L-V-R-V-V-E-K-A-V-V-A"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-Q-N-D-E-V-I-V-L-A-G-K-S-K-G-K-R-G-K-V-T-Q-V-L-P-N-G-K-V-I-V-E-G-V-N-I-I-T-K-H-E-K-P-V-P-A-L-G-K-E-G-G-L-V-K-K-E-A-A-I-D-V-S-N-V-A-I-F-N-P-K-T-N-K-A-D-R-V-G-F-R-F-E-D-G-K-K-V-R-F-F-K-S-N-N-E-I-I"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-R-D-Q-V-V-N-E-L-K-D-K-F-N-Y-K-S-V-M-Q-V-P-R-I-E-K-I-T-L-N-M-G-V-G-E-A-L-T-D-K-K-L-L-D-N-A-V-A-D-L-A-A-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-V-A-G-F-K-I-R-Q-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-E-F-F-E-R-L-I-T-I-A-V-P-R-I-R-D-F-R-G-L-S-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-Y-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-T-A-K-S-D-E-E-G-Q-A-L-L-A-A-F-N-F-P-F-R-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-D-V-K-R-V-K-L-A-E-K-F-Y-A-K-R-A-E-L-K-Q-I-I-S-D-V-N-A-S-D-E-D-R-W-N-A-V-L-K-L-Q-T-L-P-R-D-S-S-P-S-R-Q-R-N-R-C-R-Q-T-G-R-P-H-G-V-L-R-K-F-G-L-S-R-I-K-V-R-E-A-A-M-R-G-E-I-P-G-L-K-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-A-D-M-L-T-R-I-R-N-G-Q-A-A-N-K-V-A-I-S-M-P-S-S-K-L-K-V-A-I-A-N-V-L-A-E-E-G-Y-I-E-S-V-K-V-L-D-G-V-K-P-E-L-E-I-T-L-K-Y-F-Q-G-K-P-V-V-E-S-I-Q-R-V-S-R-P-G-L-R-I-Y-K-R-K-D-E-L-P-K-V-M-G-G-L-G-V-A-V-V-S-T-S-K-G-V-M-T-D-R-A-A-R-Q-A-G-L-G-G-E-I-I-C-Y-V-A"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-S-I-P-A-G-V-E-V-K-L-D-G-Q-L-L-T-V-K-G-K-N-G-E-L-S-R-T-I-H-N-A-V-E-V-K-Q-D-N-N-E-L-T-F-S-P-R-E-G-I-V-G-A-D-A-Q-A-G-T-A-R-A-L-V-N-A-M-V-I-G-V-T-E-G-F-T-K-K-L-Q-L-V-G-V-G-Y-R-A-Q-I-K-G-N-A-V-A-L-S-L-G-F-S-H-P-V-E-H-A-L-P-A-G-I-T-A-E-C-P-S-Q-T-E-I-V-L-K-G-A-D-K-Q-L-I-G-Q-V-A-A-D-I-R-A-Y-R-R-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-V-V-R-I-K-E-A-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-S-A-R-I-R-R-A-A-R-A-R-H-M-M-R-E-Q-G-V-T-R-L-V-I-H-R-T-P-R-H-I-Y-A-Q-V-I-A-P-N-G-S-E-V-L-A-A-A-S-T-V-E-K-V-I-S-E-Q-V-K-Y-T-G-N-K-D-A-A-A-V-V-G-K-V-V-A-E-R-A-L-A-K-G-V-K-D-V-A-F-D-R-S-G-F-K-Y-H-G-R-V-Q-T-L-A-D-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-N-I-E-K-Q-A-G-E-L-Q-E-K-L-I-A-V-N-R-V-S-K-T-V-K-G-G-R-I-M-S-F-T-A-L-T-V-V-G-D-G-N-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-N-M-I-N-V-A-L-N-E-G-T-L-Q-H-P-I-K-G-A-H-T-G-S-R-V-F-M-Q-P-A-S-E-G-T-G-I-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-R-N-V-L-S-K-A-Y-G-S-T-N-P-I-N-V-V-R-A-T-I-D-A-L-A-N-M-K-S-P-E-M-V-A-A-K-R-G-K-T-V-D-E-I-L-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-S-P-A-E-G-A-K-H-S-A-K-R-L-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-K-S-R-T-G-G-G-V-R-R-G-F-E-G-G-Q-M-P-L-Y-R-R-L-P-K-F-G-F-T-S-M-K-A-A-V-T-A-E-V-R-L-N-D-L-A-K-V-E-G-G-V-V-T-L-E-S-L-K-A-A-N-V-I-T-K-D-I-Q-F-V-K-I-I-L-A-G-E-V-K-G-A-V-V-V-R-G-L-R-V-T-K-G-A-K-A-A-I-E-A-A-G-G-S-V-E-E"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-H-K-H-T-V-I-A-L-T-A-I-Y-G-I-G-K-T-R-A-Q-A-I-C-A-A-T-G-I-A-E-D-V-K-I-S-E-L-S-E-E-Q-I-D-K-L-R-D-E-V-G-K-F-T-V-E-G-D-L-R-R-E-V-T-L-N-I-K-R-L-L-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-T-P-V-R-A-R-K-R-V-K-K-Q-V-V-D-G-V-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-A-W-A-T-A-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-R-C-A-E-V-V-K-E-F-G-L-K-N-L-E-V-M-V-K-G-P-G-P-G-R-E-S-T-I-R-A-L-N-A-A-G-F-R-I-T-N-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-S-I-E-P-R-K-I-L-P-D-P-K-F-G-S-E-L-L-A-K-F-I-N-V-L-M-V-D-G-K-K-S-I-A-E-K-I-V-Y-S-A-L-D-T-L-A-Q-R-T-G-K-E-A-L-E-A-F-E-A-A-L-D-N-V-R-P-T-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-P-V-R-R-N-A-L-G-M-R-W-I-V-D-A-A-R-K-R-G-D-K-S-M-A-L-R-L-A-N-E-L-S-D-A-S-E-N-K-G-A-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-R-Y-V-L-C-V-K-Q-P-A-Y-G-K-Q-G-G-F-L-A-Y-Q-L-A-K-A-L-L-E-K-G-H-Q-I-T-Q-V-F-F-F-Q-E-G-V-T-H-G-N-A-F-L-Y-P-A-S-D-E-F-N-L-Q-H-A-W-Q-R-L-A-Q-D-Y-H-V-P-L-H-L-C-V-A-A-A-Q-R-R-G-V-V-E-P-L-T-S-S-T-T-Q-Q-N-N-L-A-S-C-F-V-L-A-G-L-G-E-F-M-K-A-S-L-E-A-D-R-V-V-C-L"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-N-I-I-K-Q-L-E-Q-E-Q-L-K-Q-N-L-P-S-F-R-P-G-D-T-L-E-V-K-V-W-V-V-E-G-S-K-R-R-L-Q-A-F-E-G-V-V-I-A-I-R-N-R-G-L-H-S-A-F-T-L-R-K-V-S-N-G-V-G-V-E-R-V-F-Q-T-H-S-P-I-V-D-S-I-T-V-K-R-K-G-A-V-R-Q-A-K-L-Y-Y-L-R-E-R-S-G-K-S-A-R-I-K-E-R-L-G-D"} +{"text": "### FUNCTION This regulatory protein, when combined with SAM represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-A-N-W-D-G-K-Y-I-S-P-Y-A-E-H-G-K-K-S-E-Q-V-K-K-I-T-V-S-I-P-I-K-V-L-E-I-L-T-N-E-R-T-R-R-Q-I-R-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-F-T-G-Q-P-L-P-T-D-E-D-L-L-K-E-R-H-D-E-I-P-E-Q-A-K-Q-V-M-R-E-L-G-I-D-P-E-K-W-E-Y"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-Y-K-H-V-L-V-A-V-D-L-S-D-E-S-Q-F-L-L-E-K-A-A-G-V-A-R-R-N-E-A-K-L-S-I-I-H-V-D-V-N-F-S-D-L-Y-T-G-L-I-D-V-N-M-A-S-M-Q-D-R-I-S-T-E-T-Q-Q-S-L-V-Q-L-A-E-N-S-S-Y-P-V-A-E-K-L-S-G-S-G-D-L-G-Q-V-L-A-D-A-I-E-K-Y-D-V-D-L-L-V-T-G-H-H-Q-D-F-W-S-K-L-M-S-S-T-R-Q-V-M-N-N-I-A-V-D-M-L-V-V-P-L-R-D-E"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-E-K-I-I-I-D-E-N-Q-F-L-R-T-I-S-R-I-S-H-E-I-I-E-K-H-Q-R-L-D-N-I-V-I-V-G-I-K-R-R-G-A-E-I-A-E-L-I-K-K-K-I-A-D-L-A-N-V-E-L-P-S-I-D-L-D-I-T-F-Y-R-D-D-L-E-Y-A-E-P-D-S-K-S-P-T-Y-S-G-A-S-S-F-I-S-I-H-N-K-E-V-I-L-V-D-D-V-L-Y-T-G-R-T-I-R-A-A-L-D-A-L-V-D-F-G-R-A-A-K-I-E-L-V-I-F-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-V-P-T-S-R-S-E-E-V-Q-V-R-T-L-K-F-D-N-C-Y-E-V-A-L-L-S-P-T-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-P-G-M-I-E-R-Y-T-G-S-V-K-E-A-G-G-Q-V-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-V-L-M-N-V-E-A-P-Q-E-V-I-D-E-L-E-T-T-F-R-Y-N-D-A-V-L-R-N-V-I-I-R-T-K-H-A-V-T-E-A-S-P-M-V-K-A-K-D-D-R-K-A-L-A-E-V-E-N-N-D-F-E-D-A-E-E"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-L-K-S-N-L-N-I-D-N-R-F-S-L-I-G-I-V-A-S-Q-P-K-R-H-Q-S-P-N-G-I-Y-H-C-Q-F-V-L-E-H-R-S-I-Q-E-E-A-G-L-S-R-Q-A-W-C-K-M-P-V-Q-M-S-G-N-Q-F-R-E-K-T-Q-S-I-T-V-G-S-Q-L-L-V-V-G-F-I-S-S-H-K-T-A-N-G-L-S-Q-L-V-L-H-A-E-Q-I-E-F-I-D"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-D-K-V-V-H-L-G-N-I-G-D-Q-V-N-V-K-S-G-F-A-R-N-F-L-I-P-Q-G-K-A-V-M-A-T-K-A-N-I-E-Y-F-E-A-R-R-A-E-L-E-A-K-A-A-E-V-L-A-A-A-Q-A-R-A-A-K-L-A-E-L-G-S-V-T-I-A-S-K-A-G-D-E-G-R-L-F-G-S-I-T-T-R-D-V-A-D-A-V-T-A-A-G-V-E-V-A-K-S-E-V-R-L-S-T-G-P-I-R-T-L-G-D-H-E-V-K-F-Q-L-H-G-E-V-F-A-T-I-N-V-I-V-V-A-E"} +{"text": "### FUNCTION Globally modulates RNA abundance by binding to RNase E and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome Modulates RNA-binding and helicase activities of the degradosome ### SEQUENCE -M-Y-I-D-T-S-E-L-C-D-I-Y-L-D-Q-V-D-V-V-E-P-I-F-S-S-F-G-G-V-N-R-F-Y-G-K-V-T-T-V-K-C-F-E-N-N-G-L-I-T-D-I-L-E-E-N-G-E-G-R-V-L-L-I-D-G-G-G-A-V-R-R-A-L-V-D-A-E-L-A-Q-L-A-V-D-N-G-W-E-G-I-I-V-Y-G-A-V-R-Q-I-Q-Q-L-E-E-M-D-I-G-I-H-A-L-A-P-I-P-V-G-A-D-K-Q-N-I-G-E-I-D-V-P-V-N-F-G-G-V-T-F-F-P-E-D-Y-V-Y-A-D-L-T-G-I-I-L-S-Q-E-P-L-E-L-D-E-F-N-D-A"} +{"text": "### FUNCTION Required for nucleoid occlusion are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions ### SEQUENCE -M-Q-K-P-V-K-R-S-L-K-E-R-R-Q-Q-V-L-T-V-L-T-H-M-L-H-S-E-R-G-M-E-R-M-T-T-A-R-I-A-A-E-V-G-V-S-E-A-A-L-Y-R-Y-Y-P-S-K-T-K-M-F-E-A-L-I-D-N-L-E-A-H-L-F-T-R-I-T-Q-S-V-K-N-E-T-H-T-A-A-R-V-H-N-I-M-Q-M-V-L-D-F-A-R-K-N-P-G-L-T-R-I-L-T-G-H-A-L-M-F-E-E-P-Q-L-Q-A-R-V-A-Q-F-F-D-R-L-E-L-Q-F-I-N-I-L-Q-M-R-K-L-R-E-G-K-G-F-D-Y-E-E-R-V-I-A-A-H-L-V-N-L-C-E-G-H-F-M-R-Y-V-R-S-N-F-R-H-S-T-Q-Q-S-F-E-Q-Q-W-R-L-L-E-R-L-F-A"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-Q-G-I-H-P-N-Y-V-E-V-T-A-T-C-S-C-G-N-V-I-K-T-R-S-T-V-G-K-D-L-N-L-D-V-C-G-N-C-H-P-F-Y-T-G-K-Q-R-V-V-D-T-G-G-R-V-E-R-F-N-K-R-F-S-I-P-S-T-K"} +{"text": "### FUNCTION Component of the thioredoxin-thioredoxin reductase system Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-E-V-L-H-S-T-D-A-T-F-T-A-D-V-V-N-S-D-V-P-V-L-L-D-F-W-A-P-W-C-G-P-C-R-M-I-S-P-I-L-D-E-I-A-A-E-F-S-G-K-V-K-V-V-K-I-N-I-D-E-N-Q-A-T-P-A-Q-L-G-V-R-S-I-P-T-L-V-L-F-K-N-G-K-A-V-A-T-Q-V-G-A-L-P-K-N-Q-L-A-N-F-I-N-Q-N-I"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-G-A-V-E-K-I-G-N-R-F-D-L-I-L-T-A-A-R-R-A-R-Q-L-Q-L-H-I-R-E-P-L-V-P-E-D-N-D-K-P-T-V-I-A-L-R-E-I-E-K-G-L-I-N-N-E-I-M-N-A-Q-E-R-Y-D-A-L-E-K-E-N-S-E-L-H-A-V-S-L-L-S-N-Q"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-S-N-Y-S-Q-L-L-Q-N-A-T-W-Q-P-S-T-D-M-Q-L-P-L-S-I-S-S-W-L-E-L-S-T-S-L-T-T-Q-L-K-Q-A-F-G-E-V-N-V-C-V-L-A-E-S-W-I-T-T-L-N-E-N-E-R-Q-F-F-P-K-Q-A-C-P-C-W-C-R-E-V-I-L-K-S-Q-D-I-P-L-I-F-A-R-T-L-I-P-A-S-L-L-T-Q-H-S-E-L-Q-Q-L-G-N-R-A-L-G-E-W-L-F-M-Q-S-D-R-I-R-Q-K-L-E-L-T-H-D-K-N-T-A-L-Y-A-R-R-A-L-M-S-I-G-A-E-N-M-M-V-A-E-L-F-L-T-P-Q-I-F-T-R-V-V-K"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-Y-L-N-A-L-R-R-E-R-I-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-N-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-S-V-S-H-H-N-N-S-N-N-S-N-Q-Q-N-Y-Q-Q-E-Q-Q-T-D-S-N-V-E-K-A-E"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-R-L-V-Q-K-C-H-A-V-A-A-K-D-V-E-N-A-V-K-E-I-L-D-Q-M-S-F-A-L-E-S-G-K-R-I-E-V-R-G-F-G-S-F-S-L-H-Y-R-Q-P-R-L-G-R-N-P-K-T-G-E-Q-V-K-L-D-A-K-S-V-P-H-F-K-A-G-K-E-L-R-E-R-V-D-I-Y-A"} +{"text": "### FUNCTION Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters ### SEQUENCE -M-E-T-L-D-K-I-K-K-Q-I-S-E-N-P-I-L-I-Y-M-K-G-S-P-K-F-P-S-C-G-F-S-A-R-A-V-E-A-L-M-H-C-K-V-P-F-G-Y-V-D-I-L-Q-H-P-D-I-R-A-E-L-P-A-Y-A-N-W-P-T-F-P-Q-L-W-V-D-G-E-L-V-G-G-C-D-I-I-L-E-M-F-Q-Q-G-E-L-Q-T-L-L-A-D-V-A-A-K-Y-P-Q-E"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-T-L-E-Q-K-L-Q-E-L-L-Q-S-S-V-E-D-L-G-C-E-L-W-G-I-E-C-Q-R-A-G-R-Y-L-T-V-R-L-Y-I-D-K-E-G-G-V-T-V-E-D-C-A-D-V-S-R-Q-V-S-A-I-L-D-V-E-D-P-I-A-D-K-Y-N-L-E-V-S-S-P-G-L-D-R-A-L-F-T-L-D-Q-Y-Q-R-Y-I-G-Q-E-I-V-V-H-L-R-I-P-V-L-D-R-R-K-W-Q-G-K-L-E-K-I-E-N-D-M-L-T-L-I-V-D-G-Q-E-Q-I-L-V-F-G-N-I-Q-K-A-N-I-I-P-K-F"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-S-T-E-E-T-K-V-I-D-S-R-L-V-S-E-G-Y-Q-V-R-R-R-R-E-C-G-N-C-H-E-R-F-T-T-F-E-T-A-E-L-I-I-P-K-V-I-K-N-D-G-T-R-E-P-F-N-E-E-K-L-R-R-G-I-Q-H-A-L-E-K-R-P-V-S-E-N-D-V-E-K-A-I-S-Y-I-I-H-R-L-R-S-T-G-E-R-E-V-P-S-K-L-V-G-T-L-V-M-E-E-L-K-K-L-D-K-V-A-Y-I-R-F-A-S-V-Y-L-S-F-D-D-I-N-Q-F-S-K-E-I-E-K-L-R-D"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-F-K-F-N-A-E-V-R-Q-S-Q-G-K-G-A-S-R-R-L-R-H-N-G-Q-I-P-A-I-V-Y-G-G-S-E-A-P-V-S-I-V-L-N-H-D-D-L-N-N-A-Q-V-H-D-A-F-Y-T-D-V-I-T-L-V-I-E-G-K-E-V-A-V-K-A-Q-A-M-Q-R-H-P-F-K-P-K-L-V-H-I-D-F-K-R-V"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-L-T-K-V-E-L-A-D-N-L-I-E-K-L-H-L-N-K-R-D-A-K-E-L-V-E-N-F-F-E-E-I-R-V-A-L-E-T-G-E-D-V-K-L-S-G-F-G-N-F-E-L-R-D-K-S-S-R-P-G-R-N-P-K-T-G-E-S-V-P-V-S-A-R-R-V-V-A-F-K-P-G-Q-K-L-R-A-R-V-E-K-T-K-P-K-S"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-T-Q-Q-A-I-F-A-G-G-C-F-W-C-V-E-A-V-F-N-Q-I-K-G-V-E-K-A-T-S-G-Y-I-N-G-T-T-E-N-P-T-Y-K-E-V-C-T-G-E-T-G-H-A-E-A-V-K-V-E-F-D-A-T-V-I-S-Y-E-K-L-L-D-I-F-F-S-I-H-N-P-T-Q-L-N-H-Q-G-E-D-V-G-T-Q-Y-R-T-G-I-Y-Y-L-N-D-E-Q-E-Q-L-A-N-K-K-I-A-E-L-Q-P-H-F-A-E-K-I-V-T-E-V-L-P-A-Q-T-F-Y-P-A-E-D-Y-H-Q-G-Y-L-L-Q-N-P-Q-N-S-Y-C-N-L-V-A-T-P-K-F-L-K-A-K-V-K-F-E-E-I-W-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-A-R-H-K-K-V-L-K-A-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-A-R-Q-N-G-L-S-Y-S-K-F-I-N-G-L-K-K-A-S-V-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-V-A-F-T-A-L-V-E-K-A-K-S-A-L"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-T-V-K-K-A-P-V-A-N-R-P-N-R-I-N-D-E-I-R-V-K-E-V-R-L-I-D-Q-D-G-E-Q-A-G-I-V-S-I-Q-Q-A-L-E-M-A-E-Q-A-E-L-D-L-V-E-I-S-P-N-A-E-P-P-V-C-R-I-M-N-Y-G-K-F-L-Y-E-K-G-K-A-A-K-E-Q-K-K-K-Q-K-V-V-Q-V-K-E-I-K-F-R-P-G-T-D-E-G-D-Y-Q-V-K-L-R-S-L-I-R-F-L-E-E-G-D-K-A-K-I-T-V-R-F-R-G-R-E-M-A-H-Q-D-I-G-L-E-V-L-E-R-V-K-N-D-L-A-E-I-S-V-V-E-S-A-P-G-R-L-E-G-R-Q-A-V-M-V-L-A-P-K-K-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-K-K-S-T-E-K-T-E-L-D-F-E-N-T-L-Q-Q-L-E-A-I-V-T-R-L-E-S-G-E-L-P-L-E-S-A-L-E-E-F-E-R-G-I-K-L-A-H-L-G-Q-E-R-L-Q-Q-A-E-Q-R-I-Q-I-L-L-Q-K-S-D-S-A-K-L-S-D-Y-Q-A-E-E"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-V-A-K-P-E-T-V-K-R-D-W-Y-V-V-D-A-T-G-K-T-L-G-R-L-A-T-E-L-A-R-R-L-R-G-K-H-K-A-E-Y-T-P-H-V-D-T-G-D-Y-I-I-V-I-N-A-E-K-V-A-V-T-G-N-K-E-S-D-K-L-Y-H-W-H-T-G-Y-V-G-G-I-K-Q-A-T-F-K-E-M-I-A-R-R-P-E-A-V-I-E-I-A-V-K-G-M-L-P-K-G-P-L-G-R-A-M-Y-R-K-L-K-V-Y-A-G-S-E-H-N-H-A-A-Q-Q-P-Q-V-L-D-I"} +{"text": "### FUNCTION Required for spatial organization of the terminus region of the chromosome during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-K-L-E-N-Q-E-A-H-W-K-W-L-Y-L-I-K-K-H-R-E-G-E-N-I-T-R-Y-E-E-R-S-L-S-E-D-K-V-K-Q-L-L-S-Q-Q-N-Q-P-Q-A-I-E-N-W-I-K-A-H-L-S-P-H-L-M-I-K-L-D-Q-A-I-R-A-R-R-K-R-F-F-N-G-E-K-Q-S-T-K-K-K-S-I-D-L-E-Y-A-V-W-L-R-L-S-R-Y-S-R-K-M-K-M-T-L-S-E-T-I-T-Y-M-I-D-E-R-E-S-K-A-Q-Y-E-H-Q-I-S-A-M-K-A-G-L-K-D-L-L-K"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-M-T-E-I-S-V-P-L-I-F-T-D-A-A-A-N-K-V-K-A-L-I-S-E-E-E-N-P-N-L-K-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-K-V-N-D-G-D-L-T-I-E-K-S-G-V-H-L-V-I-D-P-M-S-L-Q-Y-L-I-G-G-T-V-D-Y-T-E-G-L-E-G-S-R-F-V-V-N-N-P-N-A-S-T-T-C-G-C-G-S-S-F-S-I"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-Q-S-T-A-R-T-L-S-V-N-K-H-I-A-L-V-A-H-D-H-C-K-Q-D-L-I-N-W-C-K-T-H-R-T-L-L-A-Q-H-T-L-Y-A-T-G-T-T-G-N-L-I-Q-K-E-A-N-L-P-I-K-S-L-L-S-G-P-M-G-G-D-Q-Q-L-G-G-L-I-A-E-K-Q-I-D-V-L-I-F-F-W-D-P-M-N-A-V-P-H-D-P-D-V-K-A-L-M-R-I-A-T-V-W-N-I-P-V-A-M-N-M-A-T-A-D-F-L-I-T-S-P-S-F-A-Q-E-T-Q-V-R-I-P-D-Y-D-G-Y-L-K-E-R-L-K"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-T-E-Y-I-L-L-I-I-S-T-A-L-I-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-I-E-T-A-I-G-M-S-L-A-T-M-F-V-L-T-V-A-S-I-S-A-Y-L-I-D-T-Y-I-L-T-P-L-S-A-T-F-L-R-T-L-V-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-V-I-N-K-T-S-P-T-L-Y-R-L-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-I-N-Q-A-H-T-L-T-Q-S-V-I-Y-G-F-G-A-S-L-G-F-G-L-V-L-V-L-F-A-A-L-R-E-R-L-A-A-A-D-V-P-H-V-F-K-G-A-S-I-A-L-I-T-A-G-L-M-S-L-A-F-M-G-F-T-G-L-V-R"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-S-E-G-Q-V-V-R-L-E-K-L-E-V-A-T-G-E-T-V-E-F-D-S-V-L-M-I-V-N-G-E-D-V-K-I-G-A-P-V-V-A-G-G-K-V-V-A-E-V-V-A-H-G-R-G-D-K-V-K-I-V-K-F-R-R-R-K-H-S-R-K-Q-Q-G-H-R-Q-W-F-T-E-V-K-I-T-G-I-Q-A"} +{"text": "### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-Y-L-S-R-N-L-E-Q-W-H-A-F-V-E-M-L-R-T-A-F-A-Q-G-K-E-Q-E-I-L-T-L-L-L-T-P-D-E-R-D-S-V-G-L-R-L-Q-I-V-A-Q-L-L-D-K-S-V-P-Q-R-E-I-Q-Q-N-L-N-T-S-A-A-T-I-T-R-G-S-N-M-I-K-T-M-P-P-E-F-M-A-W-V-K-E-Q-L-D-E-Q-A-K-K-D"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-P-F-N-I-F-D-L-P-V-D-F-H-V-D-Q-A-T-L-S-A-R-Y-L-A-L-Q-K-S-L-H-P-D-N-F-T-T-H-S-A-Q-E-Q-R-L-A-M-Q-R-S-A-E-V-N-D-A-L-Q-I-L-K-D-P-I-L-R-A-E-T-I-I-A-I-Y-T-G-E-Q-Q-N-I-E-E-N-S-T-R-D-M-A-F-L-M-Q-Q-M-Q-W-R-E-Q-L-E-N-I-E-A-Q-Q-D-S-D-Q-L-V-A-F-S-A-D-I-E-Q-T-Q-Q-A-L-L-S-E-L-A-D-A-L-S-S-Q-Q-W-Q-Q-A-K-V-I-N-D-K-L-R-F-I-K-K-L-L-L-E-V-E-R-V-E-E-K-L-L-D-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-S-T-E-K-K-A-A-I-V-A-E-F-G-R-D-A-K-D-T-G-S-S-E-V-Q-I-A-L-L-T-A-Q-I-N-H-L-Q-S-H-F-A-T-H-K-K-D-H-H-G-R-R-G-L-L-R-M-V-S-R-R-R-K-L-L-D-Y-L-K-R-T-N-L-E-L-Y-T-S-T-I-A-R-L-G-L-R-R"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-Y-Q-T-L-L-L-G-Y-A-I-I-A-I-V-I-V-F-L-I-L-I-Q-Q-G-K-G-A-D-A-G-A-S-F-G-G-G-A-S-G-T-I-F-G-S-V-G-S-G-N-F-L-S-K-M-T-A-L-L-A-T-A-F-F-V-M-S-I-V-I-G-N-V-N-S-H-R-N-N-V-K-Q-G-K-F-D-D-L-S-A-T-A-E-Q-I-Q-Q-Q-Q-K-I-D-A-P-A-V-E-T-K-N-S-D-I-P-Q"} +{"text": "### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-T-A-T-T-S-K-R-K-K-Y-V-R-E-M-K-P-T-W-W-K-K-L-D-F-Y-K-L-Y-I-A-R-E-A-T-A-I-P-T-L-W-F-C-L-V-L-L-Y-G-V-I-S-L-G-S-L-D-S-F-G-N-F-I-S-F-L-K-N-P-I-V-I-I-L-N-I-I-T-L-G-A-M-L-L-N-T-V-T-Y-Y-V-M-T-P-K-V-L-N-I-I-V-K-N-E-R-I-N-P-N-I-I-T-M-A-L-W-A-V-T-A-F-I-S-L-V-I-L-V-F-M-Y-V"} +{"text": "### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-K-D-T-P-K-R-S-N-E-P-V-V-W-L-L-F-G-A-G-T-T-V-S-A-M-F-Y-P-V-L-V-L-I-L-G-F-L-L-P-F-G-L-I-D-P-K-N-I-I-E-L-I-G-F-L-H-S-P-L-G-K-L-L-L-L-V-L-L-I-F-P-M-W-G-A-M-H-R-I-H-H-G-M-H-D-F-K-I-H-I-P-A-S-G-V-I-F-Y-G-L-S-V-L-Y-T-V-L-V-C-F-A-V-F-S-L"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-T-D-D-I-F-S-V-P-C-P-I-C-Q-K-Q-V-E-W-S-D-K-S-P-F-R-P-F-C-C-K-R-C-Q-L-I-D-L-G-E-W-A-A-E-E-K-A-I-P-C-E-S-A-D-F-A-M-N-D-E-Q-E-D-W-R-A-H"} +{"text": "### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-K-G-I-Q-I-T-Q-A-A-N-D-N-L-L-N-S-F-W-L-L-D-S-E-K-G-E-A-R-C-L-C-A-K-G-D-F-V-E-D-Q-I-V-A-V-S-E-L-G-Q-I-E-Y-R-E-L-P-V-D-I-A-P-T-V-K-V-E-G-G-Q-H-L-N-V-N-V-L-R-R-E-T-L-E-D-A-V-N-N-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-T-R-T-F-T-Q-S-L"} +{"text": "### FUNCTION Binds to type I regulatory subunits of protein kinase A and may anchor/target them to the plasma membrane ### SEQUENCE -M-G-C-M-K-S-K-E-T-F-P-F-P-T-T-L-D-I-D-K-L-H-E-S-E-E-A-F-I-P-D-D-S-S-Q-Y-R-T-P-S-P-G-E-Q-Q-Q-V-Q-E-V-K-K-L-P-E-P-G-A-V-I-G-A-L-I-L-E-F-A-D-R-L-A-S-E-I-V-E-D-A-L-Q-Q-W-A-C-E-N-I-Q-Y-Y-N-I-P-Y-I-E-S-E-G-S-D-T-T-I-N"} +{"text": "### FUNCTION Required for the assembly of the mitochondrial NADHubiquinone oxidoreductase complex Involved in the assembly of the distal region of complex I ### SEQUENCE -M-G-S-S-F-S-G-S-T-E-F-S-A-P-A-P-P-T-V-S-T-A-V-P-A-N-P-P-A-K-S-A-V-P-A-S-P-A-R-D-P-E-L-K-T-C-W-S-C-R-V-L-S-G-S-T-L-F-G-A-G-T-Y-V-Y-L-V-A-R-R-P-L-K-Q-G-I-P-P-G-P-G-T-V-L-Q-M-V-I-G-I-S-I-A-C-W-G-V-V-V-L-V-D-P-K-G-K-S-H-P-V-I"} +{"text": "### FUNCTION May modulate activity of cullin-RING E3 ubiquitin ligase complexes Down-regulates activation of NF-kappa-B ### SEQUENCE -M-R-F-R-F-C-G-D-L-D-C-P-D-W-V-L-A-E-I-S-T-L-A-K-I-S-S-V-K-L-R-L-L-C-S-Q-V-L-K-E-L-L-G-Q-G-I-D-Y-E-K-I-L-K-L-T-A-D-A-K-F-E-S-G-D-V-K-A-T-V-A-V-L-S-F-I-L-S-S-A-A-K-H-S-V-D-S-D-S-L-S-S-E-L-Q-Q-L-G-L-P-K-E-H-A-T-S-L-C-R-C-Y-E-E-K-Q-S-P-L-Q-E-H-L-R-A-C-S-L-R-V-N-R-L-A-S-V-G-W-R-V-D-Y-T-L-S-S-S-L-L-H-S-V-E-E-P-M-V-H-L-Q-L-Q-V-V-P-A-P-G-T-Q-A-Q-P-V-S-M-S-L-S-A-D-K-F-Q-V-L-L-A-E-L-K-Q-A-Q-T-M-M-T-A-L-G"} +{"text": "### FUNCTION Substrate-recognition component of the SCF -type E3 ubiquitin ligase complex ### SEQUENCE -M-A-S-W-L-P-E-T-L-F-E-I-V-G-Q-G-P-A-P-S-K-D-Y-Y-Q-L-L-I-T-R-T-Q-I-I-F-R-W-W-K-I-S-L-R-S-E-Y-R-S-A-K-P-G-E-T-K-E-S-H-E-D-F-L-D-N-S-H-L-Q-V-Q-V-A-V-V-F-G-T-K-I-L-D-Y-V-F-N-L-C-E-G-K-F-D-Y-L-E-R-L-S-D-R-L-L-L-K-I-I-C-Y-L-D-L-E-D-I-A-S-L-S-Q-T-S-S-K-F-E-K-L-C-K-S-D-L-L-W-E-Q-I-V-Q-S-T-C-D-T-I-T-P-D-M-R-A-L-A-K-N-M-G-W-R-Q-M-F-L-T-N-N-I-Q-L-Q-R-Q-T-R-K-K-K-Q-R-Q-E-N-Q-A-E-K-L-A"} +{"text": "### FUNCTION May promote cell proliferation and inhibition of apoptosis of preadipocytes ### SEQUENCE -M-T-A-A-T-R-Q-E-V-L-C-L-Y-R-S-I-F-R-L-A-R-K-W-Q-A-A-S-G-Q-M-E-D-T-I-E-E-K-Q-Y-I-L-K-E-A-R-T-L-F-Q-K-N-K-N-L-T-D-P-E-L-I-K-Q-C-I-V-E-C-T-A-R-I-E-I-G-L-H-Y-Q-I-P-Y-P-R-P-I-H-L-P-P-M-G-L-T-A-R-R-G-R-G-L-Q-T-Q-E-K-L-R-K-L-S-K-P-V-Y-L-K-S-H-D-E-V-S"} +{"text": "### FUNCTION Mitochondrial ribosome-associated protein involved in the first steps of cytochrome c oxidase complex biogenesis Stimulates the translation of MT-CO1 mRNA and is a constituent of early MT-CO1 assembly intermediates ### SEQUENCE -M-V-A-S-V-P-L-R-N-V-S-H-L-L-S-V-L-R-S-Q-N-V-P-R-Y-L-Q-N-G-V-P-R-D-V-L-L-F-R-H-E-R-G-R-F-F-A-I-L-G-L-F-C-A-G-Q-G-I-F-W-T-S-L-A-V-A-A-L-S-R-P-L-S-R-V-P-A-E-A-P-N-R-S-Y-Q-D-L-R-S-A-L-W-R-Y-G-L-A-V-G-C-G-T-M-G-V-L-V-L-G-A-G-L-L-Y-S-L-R-S-V-R-S-V-M-L-L-A-G-G-Q-Q-V-T-L-T-T-Y-A-P-F-G-L-G-T-C-F-T-V-P-L-N-Q-I-S-C-M-A-H-R-G-E-V-P-A-M-L-P-L-K-V-K-G-R-R-F-Y-F-L-L-D-K-A-G-H-F-P-N-T-Q-L-F-D-N-T-V-G-A-Y-R-S-L"} +{"text": "### FUNCTION Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-P-A-T-A-Y-E-R-V-V-Y-K-S-P-S-E-Y-H-Y-M-K-V-C-L-E-F-Q-E-H-G-V-G-L-N-V-A-Q-F-K-Q-L-L-V-S-A-L-R-D-L-F-G-E-V-G-A-A-L-P-V-D-V-L-T-Y-D-E-K-T-L-S-A-I-L-R-I-C-S-S-G-L-V-K-L-W-S-S-L-T-L-F-G-A-Y-K-S-K-K-C-A-F-R-V-I-Q-V-S-P-F-L-L-A-L-S-G-N-S-R-E-Q-V-L-D"} +{"text": "### FUNCTION Negatively regulates TSP1 expression at the level of transcription This down-regulation was shown to reduce taxane-induced apoptosis ### SEQUENCE -M-W-N-P-N-A-G-P-N-P-Y-P-P-Q-V-V-C-P-G-G-S-N-P-A-C-P-P-P-L-N-P-A-F-P-P-G-P-C-P-P-G-I-P-Q-G-N-P-A-F-P-P-C-R-P-P-Y-P-V-P-Q-P-G-C-P-G-Y-Q-P-S-G-P-Y-P-P-P-Y-P-P-P-A-P-G-M-C-P-V-N-P-P-A-P-G-M-V-G-P-G-I-V-I-D-K-K-T-R-K-K-M-K-K-A-H-K-K-S-H-K-H-H-K-H-G-K-H-S-S-S-S-S-S-S-S-S-S-D-S-D"} +{"text": "### FUNCTION E1-like enzyme which specifically catalyzes the second step in ufmylation Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage Ufmylation is involved in reticulophagy induced in response to endoplasmic reticulum stress ### SEQUENCE -M-A-D-E-A-T-R-R-V-V-S-E-I-P-V-L-K-T-N-A-G-P-R-D-R-E-L-W-V-Q-R-L-K-E-E-Y-Q-S-L-I-R-Y-V-E-N-N-K-N-S-D-N-D-W-F-R-L-E-S-N-K-E-G-T-R-W-F-G-K-C-W-Y-I-H-D-F-L-K-Y-E-F-D-I-E-F-E-I-P-I-T-Y-P-T-T-A-P-E-I-A-V-P-E-L-D-G-K-T-A-K-M-Y-R-G-G-K-I-C-L-T-D-H-F-K-P-L-W-A-R-N-V-P-K-F-G-L-A-H-L-M-A-L-G-L-G-P-W-L-A-V-E-V-P-D-L-I-Q-K-G-V-I-Q-H-K-E-K-C-S-Q"} +{"text": "### FUNCTION Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains ### SEQUENCE -M-S-Q-A-P-E-A-R-P-S-P-P-S-V-Y-H-E-R-Q-R-L-E-L-C-A-V-H-A-L-N-N-V-L-Q-E-Q-L-F-S-Q-E-A-A-D-E-I-C-K-R-L-A-P-D-S-R-L-N-P-H-R-S-L-L-G-T-G-N-Y-D-V-N-V-I-M-A-A-L-Q-G-L-G-L-A-A-V-W-W-D-R-R-R-P-L-S-Q-L-A-L-P-Q-V-L-G-L-I-L-N-L-P-S-P-V-S-L-G-L-L-S-L-P-L-R-R-R-H-W-V-A-L-R-Q-V-D-G-I-Y-Y-N-L-D-S-K-L-R-A-P-E-A-L-G-D-E-D-G-V-R-T-F-L-A-A-A-L-A-Q-G-L-C-E-V-L-L-V-V-T-K-E-V-E-E-A-G-C-W-L-N-T-S"} +{"text": "### FUNCTION Probable regulator of exocrine pancreas development ### SEQUENCE -M-A-A-I-P-S-S-G-S-L-V-A-T-H-D-Y-Y-R-R-R-L-G-S-S-S-S-S-S-S-G-G-S-A-E-Y-P-G-D-A-V-L-Q-S-P-G-L-P-K-A-D-P-G-H-W-W-A-S-F-F-F-G-K-S-T-L-P-F-M-T-T-V-L-E-S-P-E-R-S-A-E-S-P-Q-V-S-R-S-P-M-T-C-G-L-T-P-E-T-M-K-Q-Q-P-V-I-H-S-G-Q-T-N-P-R-D-L-S"} +{"text": "### FUNCTION May function as a negative regulator of endoplasmic reticulum-stress induced autophagy ### SEQUENCE -M-A-P-K-G-K-V-G-T-R-G-K-K-Q-I-F-E-E-N-K-E-T-L-K-F-Y-L-R-I-I-L-G-A-N-A-I-Y-C-L-V-T-L-V-F-F-Y-S-S-A-S-F-W-A-W-M-A-L-G-F-S-L-A-V-Y-G-A-S-Y-H-S-M-S-S-M-A-R-A-S-F-S-E-D-G-S-L-M-D-G-G-M-D-L-N-M-E-Q-G-M-A-E-H-L-K-D-V-I-L-L-T-A-I-V-Q-V-L-S-C-F-S-L-Y-I-W-S-F-W-L-L-A-P-G-R-A-L-Y-L-L-W-V-N-V-L-G-P-W-F-T-A-D-S-G-A-P-A-P-E-L-N-E-K-R-Q-R-R-Q-E-R-R-Q-M-K-R-L"} +{"text": "### FUNCTION As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor ### SEQUENCE -M-A-T-G-T-P-D-S-Q-A-R-F-G-Q-S-V-K-G-L-L-T-E-K-V-N-T-C-G-T-D-V-I-A-L-T-K-Q-V-L-K-G-S-R-S-S-E-L-L-G-Q-A-A-R-N-M-V-L-Q-E-D-A-I-L-H-S-E-D-S-L-R-K-M-A-I-I-T-T-H-L-Q-Y-Q-Q-E-A-I-Q-K-N-V-E-Q-S-P-D-L-Q-D-Q-L-S-H-L-L-K"} +{"text": "### FUNCTION May modulate the activity of casein kinase-1 Inhibits CSNK1D autophosphorylation ### SEQUENCE -M-D-P-N-P-R-A-A-L-E-R-Q-Q-L-R-L-R-E-R-Q-K-F-F-E-D-I-L-Q-P-E-T-E-F-V-F-P-L-S-H-L-H-L-E-S-Q-R-P-P-I-G-S-I-S-S-M-E-V-N-V-D-T-L-E-Q-V-E-F-I-D-L-A-D-Q-D-G-A-D-V-F-L-P-C-E-E-S-S-P-A-P-Q-M-S-G-V-D-D-H-P-E-E-L-S-L-L-V-P-T-S-D-R-T-T-S-R-T-S-S-L-S-S-D-S-S-N-L-R-S-P-N-P-S-D-G-G-G-D-T-P-L-A-Q-S-D-E-E-D-G-D-D-G-G-A-E-P-G-P-C-S"} +{"text": "### FUNCTION Client-loading PAQosome/R2TP complex cofactor that selects NOP58 to promote box C/D small nucleolar ribonucleoprotein assembly Acts as a bridge between NOP58 and the R2TP complex via RUVBL1RUVBL2 ### SEQUENCE -M-E-F-Q-G-E-R-G-T-G-P-G-V-S-S-S-S-V-A-C-S-Q-V-T-V-S-R-E-L-L-T-A-G-S-E-G-S-G-G-I-W-D-Q-L-L-I-S-S-K-P-H-P-R-K-T-S-T-L-Q-T-V-R-M-Q-R-S-P-L-L-D-Q-V-Q-A-F-L-P-Q-M-A-Q-A-N-E-K-L-R-R-E-M-A-A-A-P-A-G-H-F-N-I-E-N-I-D-E-T-S-G-N-I-I-Q-M-D-V-A-L-F-E-M-S-R-S-D-S-K-E-E-D-S-P-E-E-S-S-R-D-S-S-G-D-S-S-E-S-E-E-D-V-C-V-P-S-E-V-T-I-E-N-I-K-L-P-N-A-E-G-G-K-G-K-I-E-I-L-D-S-P-A-S-K-K-K-K-Q"} +{"text": "### FUNCTION Probably involved in translation ### SEQUENCE -M-S-T-I-Q-N-L-Q-S-F-D-P-F-A-D-A-T-K-G-D-D-L-L-P-A-G-T-E-D-Y-I-H-I-R-I-Q-Q-R-N-G-R-K-T-L-T-T-V-Q-G-I-A-D-D-Y-D-K-K-K-L-V-K-A-F-K-K-K-F-A-C-N-G-T-V-I-E-H-P-E-Y-G-E-V-I-Q-L-Q-G-D-Q-R-K-N-I-C-Q-F-L-L-E-V-G-I-V-K-E-E-Q-L-K-V-H-G-F"} +{"text": "### FUNCTION Regulates HCFC1 activity by modulating its subcellular localization Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus ### SEQUENCE -M-I-L-Q-Q-P-L-E-R-G-P-P-S-R-D-P-R-A-T-T-G-V-T-R-G-L-N-A-S-L-S-P-R-E-P-L-H-K-Q-F-L-S-E-E-N-M-A-T-H-F-S-R-L-S-L-H-N-D-H-P-Y-C-S-P-P-V-T-F-P-E-A-L-P-P-L-R-S-P-C-P-E-L-L-L-W-R-Y-P-G-S-L-I-P-E-A-L-R-L-L-R-L-G-D-T-P-S-P-Y-Y-P-A-S-P-A-G-D-I-V-E-L"} +{"text": "### FUNCTION May modulate activity of cullin-RING E3 ubiquitin ligase complexes May down-regulate activation of NF-kappa-B ### SEQUENCE -M-E-P-E-E-G-T-P-L-W-R-L-Q-K-L-P-P-E-Q-G-A-G-L-L-H-K-I-I-D-G-F-C-G-R-A-Y-P-A-H-Q-D-Y-H-S-V-W-N-S-A-E-W-K-H-V-L-E-D-V-T-T-F-F-K-A-V-V-G-K-N-F-S-E-E-E-T-L-Q-Q-L-N-Q-L-N-S-C-H-Q-E-A-V-L-K-C-L-K-S-R-R-N-E-I-K-Q-A-L-L-G-E-I-V-D-I-S-C-A-Q-L-Q-D-F-D-W-Q-L-K-L-A-L-S-S-D-K-I-A-T-L-Q-M-P-L-L-N-L-H-L-D-V-K-E-D-D-K-V-K-P-Y-T-V-E-M-S-K-E-E-L-Q-S-L-I-S-S-L-E-A-A-N-K-V-V-L-Q-L-K"} +{"text": "### FUNCTION May be involved in transcriptional regulation ### SEQUENCE -M-Q-K-S-C-D-E-N-E-G-T-P-Q-N-T-P-K-A-D-E-G-H-P-S-E-D-P-P-Q-Q-A-G-E-T-L-Q-A-S-G-E-N-V-R-E-E-T-E-G-S-H-R-G-E-P-A-E-P-S-P-E-P-K-E-D-T-P-A-R-H-L-N-P-E-E-V-I-R-G-V-D-E-L-E-R-L-R-E-E-I-R-R-V-R-N-K-F-V-L-M-H-W-K-Q-R-H-S-R-S-R-P-Y-P-V-C-F-R-P"} +{"text": "### FUNCTION Nicotinic acid adenine dinucleotide phosphate release ### SEQUENCE -M-A-A-P-P-G-E-Y-F-S-V-G-S-Q-V-S-C-R-T-C-Q-E-Q-R-L-Q-G-E-V-V-A-F-D-Y-Q-S-K-M-L-A-L-K-C-P-S-S-S-G-K-P-N-H-A-D-I-L-L-I-N-L-Q-Y-V-S-E-V-E-I-I-N-D-R-T-E-T-P-P-P-L-A-S-L-N-V-S-K-L-A-S-K-A-R-T-E-K-E-E-K-L-S-Q-A-Y-A-I-S-A-G-V-S-L-E-G-Q-Q-L-F-Q-T-I-H-K-T-I-K-D-C-K-W-Q-E-K-N-I-V-V-M-E-E-V-V-I-T-P-P-Y-Q-V-E-N-C-K-G-K-E-G-S-A-L-S-H-V-R-K-I-V-E-K-H-F-R-D-V-E-S-Q-K-I-L-Q-R-S-Q-A-Q-Q-P-Q-K-E-A-A-L-S-S"} +{"text": "### FUNCTION Inhibits phosphatase activity of protein phosphatase 1 complexes ### SEQUENCE -M-P-S-R-T-V-R-Y-A-R-Y-S-P-R-Q-R-R-R-R-M-L-A-D-R-S-V-R-F-P-N-D-V-L-F-L-D-H-I-R-Q-G-D-L-E-Q-V-G-R-F-I-R-A-R-K-V-S-L-D-T-I-H-P-S-G-L-A-A-L-H-E-A-V-L-S-G-N-L-E-C-V-K-L-L-V-K-Y-G-A-D-I-H-Q-R-D-E-T-G-W-T-P-L-H-I-A-C-S-D-G-Y-P-D-I-A-R-Y-L-I-S-L-G-A-D-R-D-A-A-N-D-D-G-D-L-P-S-D-L-I-D-P-D-F-K-D-L-V-E-L-F-K-G-T-S-M-D"} +{"text": "### FUNCTION Microtubule inner protein in cilia axoneme, which is required for motile cilia beating ### SEQUENCE -M-A-V-S-C-S-L-N-H-S-T-Y-L-Q-R-Q-N-L-V-C-Y-L-R-N-P-H-Y-G-S-L-I-Y-A-D-G-H-G-E-V-W-T-D-W-N-D-M-S-K-F-L-Q-Y-G-W-R-C-T-T-N-E-N-S-Y-S-N-R-T-L-V-G-N-W-N-Q-E-R-Y-D-L-K-N-I-V-K-P-K-P-L-P-S-Q-F-G-H-A-F-E-T-T-Y-D-A-N-Y-S-R-K-K-P-Q-S-T-H-R-F-K-R-E-P-H-W-F-P-G-H-Q-P-E-L-D-P-P-H-Y-K-C-T-A-K-S-T-Y-M-T-N-Y-S-E-P-Q-P-T-H-Y-S-C-C-V-Y-D-P-S-V-S-Q-S"} +{"text": "### FUNCTION May play a role in cell protection during the inflammatory response In epithelial cells, negatively regulates IL6 production and apoptosis through the regulation of MT2A expression ### SEQUENCE -M-K-F-P-C-L-S-F-R-Q-P-Y-A-G-L-I-L-N-G-V-K-T-L-E-T-R-W-R-P-L-L-S-S-V-Q-K-Y-T-I-A-I-H-I-A-H-K-D-W-E-D-D-E-W-Q-E-V-L-M-E-R-L-G-M-T-W-T-Q-I-Q-T-L-L-Q-A-G-E-K-Y-G-R-G-V-I-A-G-L-I-D-I-G-E-T-F-Q-C-P-E-T-L-T-A-E-E-A-V-E-L-E-T-Q-A-V-L-T-N-L-Q-L-K-Y-L-T-Q-V-S-N-P-R-W-L-L-E-P-I-P-R-K-G-G-K-D-I-F-Q-V-D-I-P-E-H-L-I-P-L-E-K-E"} +{"text": "### FUNCTION Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B ### SEQUENCE -M-T-D-Q-T-Y-C-D-R-L-V-Q-D-T-P-F-L-T-G-Q-G-R-L-S-E-Q-Q-V-D-R-I-I-L-Q-L-N-R-Y-Y-P-Q-I-L-T-N-K-E-A-E-K-F-R-N-P-K-A-S-L-R-V-R-L-C-D-L-L-S-H-L-Q-Q-R-G-E-R-H-C-Q-E-F-Y-R-A-L-Y-I-H-A-Q-P-L-H-S-H-L-P-S-R-Y-S-P-Q-N-S-D-C-R-E-L-D-W-G-I-E-S-R-E-L-S-D-R-G-P-M-S-F-L-A-G-L-G-L-A-A-G-L-A-L-L-L-Y-C-C-P-P-D-P-K-V-L-P-G-T-R-R-V-L-A-F-S-P-V-I-I-D-R-H-V-S-R-Y-L-L-A-F-L-A-D-D-L-G-G-L"} +{"text": "### FUNCTION May form part of 2 intersubunit bridges in the assembled ribosome Upon binding to MALSU1, intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation ### SEQUENCE -M-A-A-L-T-G-L-W-G-S-F-A-H-V-S-R-A-F-S-Q-R-C-F-S-T-S-G-S-L-S-A-V-Q-K-M-T-R-V-R-V-V-D-N-S-A-L-G-S-T-P-Y-H-R-P-P-R-C-I-H-V-Y-N-K-S-G-V-G-K-V-G-D-Q-I-L-L-A-I-R-G-Q-K-K-K-A-L-I-V-G-H-R-M-P-G-S-R-M-T-P-K-F-D-S-N-N-V-V-L-I-E-D-N-G-N-P-V-G-T-R-I-K-I-P-I-P-T-S-L-R-R-R-E-G-E-Y-S-K-V-L-A-I-A-Q-N-F-V"} +{"text": "### FUNCTION May have a role in proliferation and/or differentiation ### SEQUENCE -M-A-D-S-G-G-S-S-P-W-W-K-S-L-T-R-K-K-S-K-E-V-T-V-G-V-Q-P-Q-V-R-P-E-T-G-Q-E-P-S-P-P-H-S-D-R-T-S-S-L-P-E-N-Q-H-S-N-I-L-G-D-P-G-E-S-L-R-S-D-K-L-C-E-E-K-T-G-N-S-R-R-N-L-K-I-S-R-S-G-R-F-K-E-K-R-K-M-R-A-T-L-L-P-E-G-D-K-S-P-E-E-A-D-F-P-D-D-P-Q-E-D-K-Q"} +{"text": "### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-C-C-G-C-C-G-G-C-G-S-S-C-C-K-P-V-C-C-C-V-P-V-C-S-C-S-S-C-G-G-C-K-G-G-C-S-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-S-S-C-G-G-C-G-S-C-G-A-A-S-P-S-C-V-S-P-A-A-A-S-P-A-V-Q-A-L-L-L-P-V-Q-L-L-Q-A-L-L-L-P-A-Q-L-L-L-V-Q-L-L-L-S-L-L-L-L-H-D-C-G-S-S-C-C-P-M-S-C-S-L-P-I-Y-C-Q-R-E-I"} +{"text": "### FUNCTION Binds medium- and long-chain acyl-CoA esters ### SEQUENCE -M-S-L-Q-A-D-F-D-Q-A-A-Q-D-V-R-K-L-K-S-R-P-E-D-E-E-L-K-E-L-Y-G-L-Y-K-Q-S-V-I-G-D-I-N-I-A-C-P-A-M-L-D-L-K-G-K-A-K-W-E-A-W-N-L-Q-K-G-L-S-K-E-D-A-M-C-A-Y-I-S-K-A-R-E-L-I-E-K-Y-G-I"} +{"text": "### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-C-C-G-C-S-G-G-C-G-S-S-C-G-G-C-G-S-N-C-C-K-P-V-C-C-C-K-P-V-C-C-C-V-P-A-C-S-C-S-S-C-G-D-C-K-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-S-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-G-S-C-G-C-C-Q-S-S-C-C-K-P-C-C-C-Q-S-S-C-C-K-P-C-C-C-Q-S-S-C-C-Q-S-S-C-C-K-P-C-C-C-Q-S-S-C-C-K-P-C-C-C-Q-S-S-C-C-A-P-V-C-C-Q-C-K-I"} +{"text": "### FUNCTION Required for ciliogenesis ### SEQUENCE -M-L-Q-T-G-N-Y-S-L-V-L-S-L-Q-F-L-L-L-S-Y-D-L-F-V-N-S-F-S-E-L-L-R-M-A-P-V-I-Q-L-V-L-F-I-I-Q-D-I-A-I-L-F-N-I-I-I-I-F-L-M-F-F-N-T-F-V-F-Q-A-G-L-V-N-L-L-F-H-K-F-K-G-T-I-I-L-T-S-V-Y-L-A-L-S-I-S-L-H-V-W-V-M-N-V-R-W-K-N-S-S-S-F-S-W-T-N-G-L-Q-T-L-F-V-F-Q-R-L-A-A-V-L-Y-C-Y-F-Y-K-R-T-A-V-R-L-G-D-P-R-F-Y-Q-D-S-L-W-L-R-K-E-F-M-Q-V-R-R"} +{"text": "### FUNCTION May function as a specific light chain of unconventional myosin-10 ### SEQUENCE -M-A-D-Q-L-T-E-E-Q-I-A-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-S-I-T-T-Q-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-Q-G-M-V-N-E-I-D-K-D-G-N-G-T-V-D-F-P-E-F-L-T-M-M-S-R-K-M-K-D-T-D-S-E-E-E-I-R-E-A-F-R-V-F-D-K-D-G-N-G-F-V-S-A-A-E-L-R-H-V-M-T-K-L-G-E-K-L-S-D-E-E-V-D-E-M-I-Q-A-A-D-T-D-G-D-G-Q-V-N-Y-E-E-F-V-H-M-L-V-S-K"} +{"text": "### FUNCTION Exoribonuclease that is part of the telomerase RNA 3' end processing complex and which has the ability to all four unpaired RNA nucleotides from 5' end or 3' end with higher efficiency for purine bases ### SEQUENCE -M-A-A-R-G-R-R-A-E-P-P-G-R-E-A-P-G-P-A-G-S-G-R-S-R-W-A-E-S-G-P-G-T-S-P-E-S-G-D-D-E-V-S-G-S-S-P-V-S-S-G-V-N-L-F-A-N-D-G-S-F-L-E-L-F-K-R-K-M-E-E-E-Q-R-Q-R-Q-E-E-P-P-P-G-P-Q-R-P-D-P-P-A-S-A-A-A-G-P-G-N-P-K-R-K-G-G-P-G-P-T-L-S-F-V-G-K-R-R-G-G-N-K-L-A-L-K-T-G-I-V-A-K-K-Q-K-T-E-D-E-V-L-T-S-K-G-D-A-W-A-K-Y-M-A-E-V-K-K-Y-K-A-H-Q-C-G-D-D-D-K-T-R-P-L-V-K"} +{"text": "### FUNCTION May be involved in MAP kinase activation, epithelial sodium channel down-regulation and cell cycling ### SEQUENCE -M-G-T-P-A-S-V-V-S-E-P-P-L-W-Q-V-S-T-P-Q-T-R-G-R-K-Q-A-S-A-N-I-F-Q-D-A-E-L-V-Q-I-Q-G-L-F-Q-R-S-G-D-Q-L-A-E-E-R-A-Q-I-I-W-E-C-A-G-D-H-R-V-A-E-A-L-R-R-L-R-R-K-R-P-P-K-Q-N-H-C-S-R-L-R-V-P-E-P-G-S-T-A-S-D-P-Q-A-S-T-T-D-T-A-S-S-E-Q-S-G-N-S-R-R-T-S-A-R-A-P-R-N-W-N-K-P-G-P-T-G-Y-L-H-Q-I-R-H"} +{"text": "### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-A-C-C-V-A-L-C-C-S-V-P-T-G-P-A-T-T-I-C-S-S-D-K-S-C-R-C-G-V-C-L-P-S-T-C-P-H-T-I-W-Q-L-E-P-T-C-C-D-N-C-P-P-P-C-H-I-P-Q-P-C-V-P-T-C-F-L-L-N-S-C-H-P-T-P-D-L-L-T-V-N-L-T-T-Y-V-Q-P-G-C-E-E-P-C-V-P-R-C-C"} +{"text": "### FUNCTION May play a role in lysosome homeostasis ### SEQUENCE -M-V-R-I-L-A-N-G-E-I-V-Q-D-D-D-P-R-V-R-T-T-T-Q-H-R-S-S-S-S-Q-Q-G-F-F-N-R-G-H-G-A-P-P-G-G-P-G-P-R-Q-Q-Q-A-G-A-R-L-G-A-A-Q-S-P-F-S-D-L-N-R-Q-L-V-N-M-G-F-P-Q-W-H-L-G-N-H-V-V-E-P-V-T-S-I-L-L-L-F-L-L-M-M-L-G-V-R-G-L-L-L-V-G-L-V-Y-L-V-S-H-L-S-Q-R"} +{"text": "### FUNCTION Acts as a mitochondrial iron-sulfur ### SEQUENCE -M-L-S-A-R-S-A-Q-C-M-V-S-M-A-T-R-S-C-V-S-R-G-S-A-G-S-A-A-A-G-P-V-E-A-A-I-R-A-K-L-E-Q-A-L-S-P-E-V-L-E-L-R-N-E-S-G-G-H-A-V-P-A-G-S-E-T-H-F-R-V-A-V-V-S-S-R-F-E-G-M-S-P-L-Q-R-H-R-L-V-H-E-A-L-S-E-E-L-A-G-P-V-H-A-L-A-I-Q-A-K-T-P-A-Q-W-R-E-N-P-Q-L-D-I-S-P-P-C-L-G-G-S-K-K-T-R-G-T-S"} +{"text": "### FUNCTION Transcriptional repressor ### SEQUENCE -M-G-K-T-S-Q-R-K-Q-C-D-C-E-N-P-S-K-P-C-L-S-T-S-I-P-L-R-M-S-S-Y-T-F-K-R-P-V-T-K-I-T-S-H-L-G-N-E-V-R-Y-Y-Q-W-E-E-T-L-E-K-P-E-Q-A-C-W-Q-K-R-L-Q-G-L-Q-A-Y-S-S-A-G-E-L-L-S-T-S-D-L-A-K-T-L-K-D-L-T-S-T-D-T-V-A-S-A-S-D-T-Q-A-T-S-I-D-I-T-S-V-P-T-L-E-S-S-S-H-L-A-N-M-I-P-E-A-G-P-Q-I-L-C-K-E-F-L-V-T-E-Q-D-I-I-N-Q-E-R-K-V-K-I-A-R-E-R-L-A-V-A-L-I-A-H-K-L-A-S-E-M-E-T-V-R-G-S-R-K-A-N-L"} +{"text": "### FUNCTION Functions as a component of numerous distinct DCX E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex ### SEQUENCE -M-A-D-F-L-K-G-L-P-V-Y-N-K-S-N-F-S-R-F-H-A-D-S-V-C-K-A-S-N-R-R-P-S-V-Y-L-P-T-R-E-Y-P-S-E-Q-I-I-V-T-E-K-T-N-I-L-L-R-Y-L-H-Q-Q-W-D-K-K-N-A-A-K-K-R-D-Q-E-Q-V-E-A-E-G-E-S-S-A-P-P-R-K-V-A-R-T-D-S-P-D-M-P-E-D-T"} +{"text": "### FUNCTION Co-chaperone that facilitates HSP-mediated activation of TSSK6 ### SEQUENCE -M-E-Q-H-T-S-N-P-T-K-E-K-A-K-E-E-D-S-V-A-C-F-C-P-A-K-S-S-P-S-Y-I-D-L-P-A-N-F-T-P-A-N-F-L-T-I-Q-T-K-L-S-S-G-A-G-Q-K-P-K-G-C-L-G-V-L-E-C-M-Y-A-N-L-Q-L-Q-T-Q-L-A-Q-R-Q-I-A-I-L-E-N-L-Q-A-S-L-S-Q-P-G-S-G-R-E-S-K-N-C-S-L-P-G-L-C-C-K-L-L-L-N-H-L-P-Q-F-H-K"} +{"text": "### FUNCTION May play a role in lipid transport ### SEQUENCE -M-V-D-Q-L-Q-G-T-W-K-S-V-S-C-D-N-F-E-N-Y-M-K-E-L-G-V-G-R-A-S-R-K-L-G-C-L-A-K-P-T-V-T-I-S-T-D-G-D-L-I-T-I-K-T-K-S-I-F-K-N-K-E-I-S-F-K-L-G-E-E-F-E-E-T-T-P-S-G-R-K-S-K-S-T-V-I-L-D-N-D-S-L-V-Q-V-Q-D-W-D-G-K-E-A-T-I-C-R-R-L-V-D-G-K-M-V-V-E-S-A-V-N-N-V-T-C-T-R-T-Y-Q-R-V"} +{"text": "### FUNCTION May play a role in bone development ### SEQUENCE -M-N-Q-A-D-K-N-Q-E-I-P-S-Y-L-S-D-E-P-P-E-G-S-M-K-D-H-P-Q-Q-Q-P-G-M-L-S-R-V-T-G-G-I-F-S-V-T-K-G-A-V-G-A-T-I-G-G-V-A-W-I-G-G-K-S-L-E-V-T-K-T-A-V-T-T-V-P-S-M-G-I-G-L-V-K-G-G-V-S-A-V-A-G-G-V-T-A-V-G-S-A-V-V-N-K-V-P-L-S-G-K-K-K-D-K-S-D"} +{"text": "### FUNCTION Microtubule inner protein in cilia axoneme, which is required for motile cilia beating ### SEQUENCE -M-E-E-L-A-K-K-E-R-R-A-M-D-P-G-G-L-K-K-E-G-K-V-E-E-E-A-G-K-E-E-G-R-E-E-E-G-G-E-E-E-E-V-T-S-E-T-L-R-G-K-P-R-P-L-P-I-S-A-L-P-A-F-S-Y-I-P-P-R-H-Q-G-P-K-E-R-S-Y-F-S-R-E-G-Q-T-G-I-V-S-L-Y-D-C-V-F-K-R-R-L-D-Y-N-Q-K-L-H-R-D-D-R-E-H-A-K-N-L-G-L-H-I-N-E-E-E-Q-E-R-T-V-P-V-L-M-S-S-V-Y-G-K-R-I-N-Q-P-I-E-P-L-N-R-D-Y-G-H-V-S-H-V-K-T-D-F-Y-R-K-N-E-I-P-S-I-K-G-P-G-F-G-H-I-N-P-A"} +{"text": "### FUNCTION May be involved in induction of apoptosis in CD4 T-cells or hepatocytes ### SEQUENCE -M-A-T-P-W-R-R-A-L-L-M-I-L-A-S-Q-V-V-T-L-V-K-C-L-E-D-D-D-V-P-E-E-W-L-L-L-H-V-V-Q-G-Q-I-G-A-G-N-Y-S-Y-L-R-L-N-H-E-G-K-I-I-L-R-M-Q-S-L-R-G-D-A-D-L-Y-V-S-D-S-T-P-H-P-S-F-D-D-Y-E-L-Q-S-V-T-C-G-Q-D-V-V-S-I-P-A-H-F-Q-R-P-V-G-I-G-I-Y-G-H-P-S-H-H-E-S-D-F-E-M-R-V-Y-Y-D-R-T-V-D-Q-Y-P-F-G-E-A-A-Y-F-T-D-P-T-G-A-S-Q-Q-Q-A-Y-A-P-E-E-A-A-Q-E-E-E-S-V-L-W-T-I-L-I-S-I-L-K-L-V-L-E-I-L-F"} +{"text": "### FUNCTION May be involved in transcriptional regulation ### SEQUENCE -M-K-P-C-Q-K-M-E-G-N-L-E-K-E-D-E-P-K-P-E-E-E-P-K-P-E-E-K-P-E-E-G-Q-E-P-E-E-E-E-K-S-E-E-T-F-R-E-R-L-I-R-S-L-Q-D-F-Q-E-D-I-H-N-R-H-L-S-S-D-D-L-F-R-D-V-E-E-L-D-E-I-R-K-V-R-N-K-L-I-V-T-R-W-K-A-N-R-S-H-P-Y-P-Y-L-M"} +{"text": "### FUNCTION Antagonist of muscle and neuronal nicotinic acetylcholine receptors with highest affinity for neuronal alpha-7/CHRNA7 nAChRs ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-M-V-C-M-D-L-G-Y-T-T-I-C-Y-N-H-L-S-R-T-P-E-T-T-E-I-C-P-D-S-W-Y-F-C-Y-K-I-S-L-A-D-G-N-D-V-R-I-K-R-G-C-T-F-T-C-P-E-L-R-P-T-G-K-Y-V-Y-C-C-R-R-D-K-C-N-Q"} +{"text": "### FUNCTION Plays an important role in the organization of the cytoskeleton Binds to and sequesters actin monomers ### SEQUENCE -M-C-D-K-P-D-L-S-E-V-E-K-F-D-K-K-K-L-K-K-T-N-T-E-E-K-N-T-L-P-S-K-E-T-I-E-Q-E-K-E-C-V-K-S-S"} +{"text": "### FUNCTION Seems to act as a signaling molecule involved in the maintenance of iron homeostasis Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages May also have antimicrobial activity ### SEQUENCE -L-Q-V-L-T-E-E-V-G-S-I-D-S-P-V-G-E-H-Q-Q-P-G-G-E-S-M-R-L-P-E-H-F-R-F-K-R-X-S-H-L-S-L-C-R-W-C-C-N-C-C-H-N-K-G-X-G-F-C-C-K-F"} +{"text": "### FUNCTION May regulate transcription ### SEQUENCE -M-L-S-W-L-K-G-H-K-R-Y-C-R-F-K-D-C-T-C-E-K-C-I-L-I-I-E-R-Q-R-V"} +{"text": "### FUNCTION Plays an important role in the organization of the cytoskeleton Binds to and sequesters actin monomers ### SEQUENCE -M-S-D-K-P-D-V-K-E-V-E-S-F-D-K-T-T-L-K-K-T-T-T-N-E-K-N-T-L-P-T-K-E-V-I-E-Q-E-K-S-G-G-S-D"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-K-V-E-L-C-S-F-S-G-Y-K-I-Y-P-G-H-G-R-R-Y-A-R-I-D-G-K-V-F-Q-F-L-N-A-K-C-E-S-A-F-L-A-K-R-N-P-R-Q-I-N-W-T-V-L-Y-R-R-K-H-K-K-G-Q-S-E-E-V-T-K-K-R-T-R-R-A-V-K-F-Q-R-A-I-T-G-A-S-L-A-E-I-M-A-K-R-N-Q-K-P-E-V-R-K-A-Q-R-E-Q-A-I-R-A-A-K-E-S-K-K-A-K-Q-A-T-K-K-P-A-A-A-S-A-K-T-S-A-K-T-A-Q-K-P-K-I-A-K-P-M-K-I-S-A-P-R-V-G-G-K-R"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell Required for pre-rRNA processing and maturation of 40S ribosomal subunits ### SEQUENCE -M-P-G-V-T-V-K-D-V-N-Q-Q-E-F-V-R-A-L-A-A-F-L-K-K-S-G-K-L-K-V-P-D-W-V-D-L-V-K-L-G-R-H-K-E-L-A-P-S-D-E-N-W-F-Y-I-R-A-A-S-T-V-R-H-L-Y-L-R-G-G-A-G-V-G-S-M-T-K-I-Y-G-G-R-Q-R-N-G-V-C-P-A-H-Y-S-E-G-S-K-N-V-A-R-K-V-L-Q-A-L-E-L-L-K-M-I-E-K-D-P-N-G-G-R-R-L-T-A-Q-G-T-R-D-L-D-R-I-A-G-Q-V-S-A-A-S-K-K-I-V-Q"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-G-R-M-H-A-P-G-K-G-L-S-Q-S-A-L-P-Y-R-R-S-V-P-T-W-L-K-L-T-S-D-D-V-K-E-Q-I-F-K-L-A-K-K-G-L-T-P-S-Q-I-G-V-I-L-R-D-S-H-G-V-A-Q-V-R-F-V-T-G-N-K-I-L-R-I-L-K-S-K-G-L-A-P-D-L-P-E-D-L-Y-H-L-I-K-K-A-V-A-V-R-K-H-L-E-R-N-R-K-D-K-D-A-K-F-R-L-I-L-I-E-S-R-I-H-R-L-A-R-Y-Y-K-T-K-R-V-L-A-P-N-W-K-Y-X-S-S-T-A-S-A-L-V-A"} +{"text": "### FUNCTION Transcriptional activator that mediates FGF signaling during neural development ### SEQUENCE -M-C-G-G-C-V-G-T-E-Y-P-E-R-G-T-T-C-L-E-G-G-S-F-L-L-N-F-V-G-C-A-R-C-G-R-R-D-F-V-L-L-G-N-R-A-A-G-L-H-G-D-D-E-I-I-T-Y-D-H-L-C-K-N-C-H-H-L-I-A-R-H-E-Y-T-F-S-V-V-D-D-Y-Q-E-Y-T-M-L-C-L-L-C-G-R-A-E-D-S-V-S-I-L-P-D-D-P-R-Q-M-T-P-L-F"} +{"text": "### FUNCTION Transcriptional activator that mediates FGF signaling during neural development ### SEQUENCE -M-C-G-G-C-V-Q-Q-E-Y-P-D-R-G-S-T-C-L-E-T-G-S-Y-L-L-N-Y-V-S-C-V-Q-C-N-K-R-D-F-V-L-I-V-N-K-T-A-A-E-E-D-G-E-E-I-I-T-Y-D-H-M-C-K-N-C-H-H-V-I-A-K-H-E-Y-T-F-S-V-V-D-D-Y-Q-E-Y-T-M-L-C-M-L-C-G-R-A-E-D-S-V-S-V-L-P-D-D-P-R-Q-M-A-P-L-F"} +{"text": "### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-V-V-K-T-W-M-P-W-L-L-V-S-S-V-L-S-Q-G-C-C-Q-H-W-S-F-G-L-S-P-G-G-K-R-E-L-K-Y-F-P-N-T-L-E-N-Q-I-R-L-L-N-S-N-T-P-C-S-D-L-S-H-L-E-E-S-S-L-A-K-I-Y-R-I-K-G-L-L-G-S-V-T-E-A-K-N-G-Y-R-T-Y-K"} +{"text": "### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-K-L-V-P-L-F-Y-K-T-C-P-A-G-K-N-L-C-Y-K-I-F-M-V-A-T-P-K-V-P-V-K-R-G-C-I-D-V-C-P-K-N-S-A-L-V-K-Y-V-C-C-N-T-D-R-C-N"} +{"text": "### FUNCTION Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles ### SEQUENCE -M-A-D-L-D-A-V-L-K-C-W-G-A-V-E-A-D-F-N-T-V-G-G-L-V-L-A-R-L-F-K-D-H-P-E-T-Q-K-L-F-P-K-F-A-G-I-T-G-D-I-A-G-N-A-A-V-A-A-H-G-A-T-V-L-K-K-L-G-E-L-L-K-A-K-G-N-H-A-A-I-I-K-P-L-A-N-S-H-A-K-Q-H-K-I-P-I-N-N-F-K-L-I-T-E-A-L-A-H-V-L-H-E-K-A-G-L-D-A-A-G-Q-T-A-L-R-N-V-M-G-I-V-I-A-D-L-E-A-N-Y-K-E-L-G-F-T-G"} +{"text": "### FUNCTION Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles ### SEQUENCE -M-A-D-F-D-A-V-L-K-F-W-G-P-V-E-A-D-Y-D-K-I-G-N-M-V-L-T-R-L-F-T-E-H-P-D-T-Q-K-L-F-P-K-F-A-G-I-G-L-G-D-M-A-G-N-A-A-I-S-A-H-G-A-T-V-L-K-K-L-A-E-V-L-K-A-K-G-N-H-A-G-I-I-K-P-L-A-N-S-H-A-T-K-H-K-I-A-I-N-N-F-K-L-I-T-E-I-I-V-K-V-M-Q-E-K-A-G-L-D-A-G-G-Q-T-A-L-R-N-V-M-G-V-F-I-A-D-M-D-A-N-Y-K-E-L-G-F-S-G"} +{"text": "### FUNCTION Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles ### SEQUENCE -M-A-D-F-D-A-V-L-K-F-W-G-P-V-E-A-D-Y-T-S-H-G-G-L-V-L-T-R-L-F-K-E-H-P-E-T-Q-K-L-F-P-K-F-T-G-I-A-Q-A-D-M-A-G-N-A-A-I-S-A-H-G-A-T-V-L-K-K-L-G-E-L-L-K-A-K-G-N-H-A-A-I-L-K-P-M-A-N-S-H-A-T-K-H-K-I-P-I-N-N-F-K-L-I-S-E-I-I-V-K-V-M-Q-E-K-A-G-M-D-A-G-G-Q-Q-A-L-R-N-V-M-A-A-V-I-A-D-L-E-A-N-Y-K-E-L-G-F-S-G"} +{"text": "### FUNCTION Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles ### SEQUENCE -M-A-D-F-E-M-V-L-K-H-W-G-P-V-E-A-D-Y-A-T-H-G-N-L-V-L-T-R-L-F-T-E-H-P-E-T-Q-K-L-F-P-K-F-A-G-I-A-K-A-D-M-A-G-N-A-A-I-S-A-H-G-A-T-V-L-K-K-L-G-E-L-L-K-A-K-G-S-H-A-A-I-I-K-P-M-A-N-S-H-A-T-K-H-K-I-P-I-K-N-F-E-L-I-S-E-V-I-G-K-V-M-H-E-K-A-G-L-D-A-A-G-Q-K-A-L-K-N-V-M-T-T-I-I-A-D-I-E-A-N-Y-K-E-L-G-F-T-G"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-I-I-Y-K-D-I-I-T-G-D-E-M-F-S-D-I-Y-K-I-K-E-S-E-N-G-M-M-L-E-V-E-G-K-M-I-T-R-A-E-G-D-I-D-D-A-L-I-G-G-N-A-S-A-E-V-A-D-E-G-C-D-S-T-S-V-S-G-V-D-I-V-L-N-H-K-L-Q-E-T-S-Y-D-K-K-S-Y-T-A-Y-I-K-D-Y-M-K-A-V-K-A-K-L-Q-E-S-A-P-N-R-V-D-P-F-M-A-N-A-P-A-E-V-K-K-I-L-G-N-I-K-N-F-Q-F-F-T-G-E-S-M-N-P-D-G-M-I-G-L-L-D-F-R-E-D-G-V-T-P-Y-M-I-F-F-K-D-G-L-E-I-E-K-C"} +{"text": "### FUNCTION NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone ### SEQUENCE -M-H-P-N-M-K-M-W-I-G-W-A-A-C-A-F-L-L-F-A-C-L-G-T-L-T-E-G-Y-P-T-K-P-D-N-P-G-E-D-A-P-A-E-E-L-A-K-Y-Y-S-A-L-R-H-Y-I-N-L-I-T-R-Q-R-Y-G-K-R-S-S-A-D-T-L-I-S-D-L-L-I-G-E-T-E-S-H-P-Q-T-R-Y-E-D-H-L-V-W"} +{"text": "### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-N-P-S-S-V-F-L-I-V-V-A-T-V-A-I-C-L-I-V-I-Q-V-Y-Y-I-Y-E-N-Y-D-N-I-K-E-F-N-S-T-H-S-L-L-E-Y-S-K-T-I-N-V-F-S-L-D-R-R-I-Y-D-P-N-D-H-V-H-D-V-K-Q-K-W-R-C-V-N-Y-D-N-N-Y-V-S-V-S-I-F-G-F-K-S-D-S-G-K-N-I-K-N-F-S-T-V-D-D-C-I-D-Y-T-F-S-K-S-T-H-S-N-I-F-N-P-C-I-N-E-D-K-S-K-D-C-N-F-L-K-S-V-L"} +{"text": "### FUNCTION Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates Responsible for the transcription of early, intermediate and late genes DNA-dependent RNA polymerase associates with the early transcription factor ### SEQUENCE -M-V-F-Q-L-I-C-S-T-C-G-R-D-I-S-E-E-R-Y-Y-L-L-I-K-E-L-S-L-K-K-V-L-E-G-V-K-N-N-C-C-R-L-K-L-S-T-Q-I-E-P-Q-R-N-L-T-V-Q-P-L-I-D-I-N"} +{"text": "### FUNCTION Increases viral DNA accumulation Enhances infectivity and symptom expression ### SEQUENCE -M-D-S-R-T-G-E-L-L-T-A-A-Q-S-E-N-G-V-Y-I-W-T-V-K-N-P-L-Y-F-K-I-T-K-H-H-E-R-P-F-L-R-N-H-D-I-I-T-I-Q-V-Q-F-N-Y-N-L-R-K-A-L-G-I-H-K-C-F-L-T-C-Q-I-W-T-R-L-H-P-Q-T-S-H-F-L-R-V-F-K-Y-Q-F-I-K-Y-L-D-R-L-G-V-I-S-I-N-N-C-I-R-A-F-S-H-V-L-Y-D-V-L-N-G-T-I-D-V-I-E-K-H-D-I-K-F-N-I-Y"} +{"text": "### FUNCTION Through its interaction with host SGS3, acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing , a mechanism of plant viral defense that limits the accumulation of viral RNAs ### SEQUENCE -M-W-D-P-L-L-N-E-F-P-E-T-V-H-G-F-R-C-M-L-A-I-K-Y-L-Q-L-V-E-N-T-Y-S-P-D-T-L-G-Y-D-L-I-R-D-L-I-S-V-I-R-A-R-D-Y-G-E-T-S-R-R-Y-C-H-F-H-S-R-L-E-G-A-S-P-A-E-L-R-Q-P-L-Y-G-S-C-C-C-P-H-C-P-R-H-Q-K-T-N-V-V-K-Q-A-H-V-P-E-A-H-D-V-P-D-V-Q-K-P"} +{"text": "### FUNCTION Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly ### SEQUENCE -M-S-R-A-S-S-Q-Q-A-S-P-T-S-Q-T-F-D-P-S-D-L-S-T-Y-T-L-D-V-L-H-H-Y-P-L-V-D-L-L-Q-Q-L-N-A-I-P-N-D-L-K-I-P-D-T-Y-S-K-V-E-Q-A-A-R-I-N-V-L-R-A-I-C-V-G-F-A-E-V-R-R-H-N-D-N-R-T-L-Q-R-S-T-M-F-A-V-N-D-A-A-S-R-I-R-P-S-I-G-L-K-R-T-F-P-T-G-I-F-S-T-T-I-H-G-S-P-S-D-D-D-I-S-T-S"} +{"text": "### FUNCTION Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm Once the complex reaches the host nucleus, it interacts with the capsid portal vertex This portal forms a ring in which genomic DNA is translocated into the capsid ### SEQUENCE -M-A-G-E-N-T-S-R-R-T-G-S-A-R-L-D-E-V-I-P-E-F-E-L-V-S-T-D-V-K-I-L-A-E-K-Y-L-Q-D-E-R-I-Y-R-I-W-F-E-Y-L-I-P-D-E-I-D-L-I-F-P-T-T-D-G-K-L-N-Y-L-S-F-T-K-R-L-A-S-A-I-R-Y-G-R-I-K-T-A-V-S-N-N-S-S-S-N-S-Y-G-S-T-E-H-V-C-D-H-G-T-S-L-C-G-R-S-E-R-F-A-S-V-I-N-R-F-L-D-L-H-Q-I-L-K-D-C"} +{"text": "### FUNCTION Plays a major role in assembly and budding of virion Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form Inhibits viral transcription and stimulates replication ### SEQUENCE -M-S-A-K-L-N-W-Y-R-I-T-F-N-D-T-V-W-R-F-D-T-A-R-G-P-K-D-G-E-T-C-P-L-I-A-S-E-L-F-S-S-G-L-S-E-V-F-K-S-V-T-S-F-S-E-I-L-R-N-M-E-S-R-G-Y-I-T-N-I-T-L-R-A-D-S-D-I-L-G-P-G-A-L-R-C-E-F-L-F-P-S-E-V-F-I-P-T-S-H-T-L-K-M-G-R-S-S-L-I-L-E-P-H-L-V-V-L-K-E-C-K-Y-I-S-S-G-K-L-D-I-G-I-S-S-I-E-A-T-S-V-A-V-L-R-R-V-K-G-P-A-F-I-G-C-M-D-D-N-P-F-G-V-L-T-K-K-P-S-D-E-K-N-V-L-A-S-K"} +{"text": "### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-S-D-K-T-V-K-S-T-N-L-M-A-F-I-A-T-K-M-L-E-R-Q-E-D-L-D-T-C-T-E-M-Q-V-E-K-M-K-T-S-T-K-A-R-L-R-T-E-S-S-F-A-P-R-T-W-E-D-A-I-K-D-E-I-L-R-R-S-V-D-T-S-S-L-D-K-W-P-E-L-K-Q-E-L-E-N-V-S-D-A-L-K-A-D-S-L-W-L-P-M-K-S-L-S-L-Y-S-K-V-S-N-Q-E-P-N-S-I-P-I-G-E-M-K-H-Q-I-L-T-R-L-K-L-I-C-S-R-L-E-K-L-D-L-N-L-S-K-A-V-L-G-I-Q-N-S-E-D-L-I-L-I-I-Y-N-R-D-I-C-K-T-T-I-L-M-I-K-S-L-C-N-S-L-I"} +{"text": "### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-S-D-K-T-V-K-S-T-N-L-M-A-F-V-A-T-K-M-L-E-R-Q-E-D-L-D-T-C-T-E-M-Q-V-E-K-M-K-T-S-T-K-A-R-L-R-T-E-S-S-F-A-P-R-T-W-E-D-A-I-K-D-E-I-L-R-R-S-V-D-T-S-S-L-N-K-W-P-E-L-K-Q-E-L-E-N-V-S-D-A-L-K-A-D-S-L-W-L-P-M-K-S-L-S-L-Y-S-K-V-S-N-Q-E-P-S-S-I-P-I-G-E-M-K-H-Q-I-L-T-R-L-K-L-I-C-S-R-L-E-K-L-D-L-N-L-S-K-A-V-L-G-I-Q-N-S-E-D-L-I-L-I-I-Y-N-R-D-V-C-K-N-T-I-L-M-I-K-S-L-C-N-S-L-I"} +{"text": "### FUNCTION Has antibacterial activity ### SEQUENCE -M-K-I-H-Y-L-L-F-A-F-L-L-V-L-L-S-P-L-A-G-V-F-S-K-T-I-N-N-P-V-S-C-C-M-I-G-G-I-C-R-Y-L-C-K-G-N-I-L-Q-N-G-S-C-G-V-T-S-L-N-C-C-K-R-K"} +{"text": "### FUNCTION Promotes cell adhesion to laminin and fibronectin ### SEQUENCE -M-A-K-N-G-L-V-L-C-I-L-V-V-S-L-L-L-D-Q-T-D-G-Y-P-S-R-M-K-A-R-K-H-S-K-R-R-V-K-A-K-D-D-D-L-K-S-Q-V-E-K-L-W-R-E-V-N-A-L-K-E-M-Q-A-L-Q-T-V-C-L-R-G-T-K-V-H-K-K-C-Y-L-A-S-E-G-L-K-H-Y-H-E-A-N-E-D-C-I-S-K-G-G-T-L-V-V-P-R-N-S-D-E-I-N-A-L-R-D-Y-G-K-R-S-L-P-G-V-N-D-F-W-L-G-I-N-D-M-V-T-E-G-K-F-L-D-V-H-G-F-A-V-S-F-L-N-W-D-R-A-Q-P-S-G-G-K-R-E-N-C-V-L-F-S-Q-S-A-Q-G-K-W-S-D-E-A-C-R-S-S-K-R-Y-I-C-E-F-I-I-P"} +{"text": "### FUNCTION Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1 ### SEQUENCE -M-D-W-P-H-S-L-L-F-L-L-A-I-S-I-F-L-G-P-S-Q-P-R-N-T-K-G-K-R-K-G-Q-V-R-P-G-P-L-A-P-G-P-H-Q-V-P-L-D-L-V-S-R-V-K-P-Y-A-R-M-E-E-Y-E-R-N-L-G-E-M-V-A-Q-L-R-N-S-S-E-P-A-K-R-R-C-E-V-N-L-Q-L-W-L-S-N-K-R-S-L-S-P-W-G-Y-S-I-N-H-D-P-S-R-I-P-A-D-L-P-E-A-R-C-L-C-L-G-C-V-N-P-F-T-M-Q-E-D-R-S-M-V-S-V-P-V-F-S-Q-V-P-V-R-R-R-L-C-P-P-P-P-R-P-G-P-C-R-H-R-V-V-M-E-T-I-A-V-G-C-T-C"} +{"text": "### FUNCTION Probable transcription factor involved in the control of specification of mesoderm and endoderm ### SEQUENCE -M-A-S-P-V-E-A-S-P-G-C-A-S-G-L-G-P-H-R-R-K-R-T-T-F-S-V-G-Q-L-L-E-L-E-R-V-F-A-A-R-P-Y-P-D-I-S-T-R-E-H-L-A-Q-I-T-H-L-P-E-A-K-I-Q-V-W-F-Q-N-R-R-A-K-R-I-K-D-R-K-P-G-A-L-N-A-R-L-E-L-P-P-N-C-S-L-P-D-T-P-Q-L-S-W-D-P-G-T-P-S-H-P-L-H-S-T-S-S-A-Q-Q-T-S-A-C-P-P-Q-T-S-C-L-A-P-I-L-G-P-G-Q-S-W-S-G-A-K-A-A-A-P-W-G-T-S-E-V-S-G-V-H-S-L-E-Q-I-V-P-Q-T-S-L-G-N-L-S-D-L-I-Y-T-S-A-I-V-T-N-V-D-H-S"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-E-I-T-V-E-L-V-S-V-E-R-M-L-W-A-G-Q-A-S-I-V-T-A-Q-T-T-E-G-E-I-G-V-L-P-D-H-E-P-L-L-G-Q-L-V-E-N-G-V-V-T-I-Q-P-I-D-G-E-K-L-I-A-G-V-S-D-G-F-L-S-V-S-K-E-K-V-T-I-L-A-D-F-A-V-W-A-N-E-V-D-T-A-S-A-E-A-D-L-N-S-D-D-E-L-A-K-A-H-A-E-A-G-L-R-A-V-R-R-S-S-E-G-L"} +{"text": "### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation ### SEQUENCE -M-N-W-I-V-I-D-T-V-I-Q-P-A-C-D-I-S-F-S-A-I-W-C-N-I-K-L-I-L-W-Y-Q-S-D-I-F-L-P-P-G-C-I-F-T-P-T-R-T-G-V-I-L-N-N-K-E-L-P-V-T-I-Y-N-V-T-P-F-N-K-N-V-W-N-L-I-K-S-S-Q-E-C-P-A-N-T-G-N-I-T-D-K-C-F-N-H-R-C-I-L-E-I-C-P-Y-G-R-K"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-S-T-L-A-K-I-E-A-L-L-F-V-R-G-E-D-W-I-R-V-R-Q-L-A-E-L-L-S-L-P-P-T-G-I-Q-Q-S-L-E-K-L-S-Q-K-Y-E-K-D-L-D-S-S-L-D-L-I-E-T-G-G-A-Y-R-L-V-T-K-P-Q-F-S-E-I-L-K-E-Y-S-K-A-P-I-N-Q-S-L-S-R-P-A-L-E-T-L-S-I-I-A-Y-K-Q-P-I-T-R-I-E-I-D-A-I-R-G-V-N-S-S-G-A-L-A-K-L-Q-A-F-D-L-I-R-E-D-G-K-K-E-V-L-G-R-P-N-L-Y-V-T-T-D-Y-F-L-D-Y-M-G-I-N-H-L-E-E-L-P-V-I-D-E-L-E-I-Q-A-Q-E-S-Q-L-F-G-E-R-I-E-E-D-E-N-Q"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-S-G-K-G-A-P-E-L-S-V-R-N-V-G-D-L-R-V-A-V-I-A-S-Q-W-H-D-K-V-M-D-G-L-V-D-G-A-L-R-A-L-H-E-L-G-I-D-E-P-T-L-L-R-V-P-G-S-F-E-L-P-V-V-A-K-V-L-A-G-R-G-Y-D-A-I-V-A-L-G-V-V-I-R-G-G-T-P-H-F-D-Y-V-C-Q-G-V-T-Q-G-L-V-Q-V-S-V-E-T-G-V-P-V-G-F-G-V-L-T-C-D-T-E-E-Q-A-L-D-R-A-G-I-E-G-S-S-E-D-K-G-H-E-A-V-T-A-A-V-A-T-A-A-T-L-R-S-V-S-E-P-W-R"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-G-S-V-R-K-A-S-A-W-L-G-L-V-D-D-N-N-D-D-E-R-Y-Y-D-D-D-Y-S-E-G-P-E-S-G-D-A-W-V-T-D-P-R-V-K-V-A-S-D-V-A-E-E-K-G-R-R-I-A-T-V-T-P-D-S-F-R-D-A-R-A-I-G-E-L-F-R-D-G-V-P-V-I-V-N-L-T-A-M-E-G-T-D-A-K-R-V-V-D-F-A-A-G-L-I-F-G-L-R-G-S-I-E-R-V-S-T-R-V-F-L-L-S-P-A-D-T-Q-V-I-S-G-E-S-A-A-H-R-S-D-G-F-F-N-Q-S"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-D-A-I-Q-I-V-M-F-V-M-A-I-L-C-L-I-I-G-L-L-L-S-N-H-G-S-T-G-G-L-A-S-L-S-G-Q-D-L-E-I-F-R-K-T-K-D-R-G-I-V-K-I-L-Q-I-T-M-F-I-L-V-V-L-F-L-I-L-G-L-V-F-H-F-A-L"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-R-I-S-D-A-A-Q-A-H-F-A-K-L-L-A-N-Q-E-E-G-T-Q-I-R-V-F-V-I-N-P-G-T-P-N-A-E-C-G-V-S-Y-C-P-P-D-A-V-E-D-T-D-T-A-L-K-F-E-Q-L-T-A-Y-V-D-E-L-S-A-P-Y-L-E-D-A-E-I-D-F-V-T-D-Q-L-G-S-Q-L-T-L-K-A-R-T-P-K-C-A-K"} +{"text": "### FUNCTION Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone biosynthetic pathway ### SEQUENCE -M-T-A-D-A-P-V-I-S-G-S-S-V-V-K-L-A-R-G-V-R-L-H-E-D-P-V-R-G-Q-T-V-L-L-A-P-E-R-A-M-A-V-D-D-I-A-V-A-I-V-Q-A-L-D-G-E-R-N-L-D-R-I-A-A-D-F-A-E-K-F-D-A-P-V-E-E-I-A-E-D-V-R-T-F-V-Q-E-L-S-V-R-R-M-L-E-I-V-Q"} +{"text": "### FUNCTION Required for coenzyme pyrroloquinoline quinone ### SEQUENCE -M-A-W-H-K-P-K-F-I-E-V-S-C-A-M-E-I-T-R-Y-A-P-A-D-G-D-E-P-I-L-F"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-F-G-I-T-Q-N-I-V-A-I-V-T-E-H-A-K-G-A-K-V-Q-R-V-L-L-E-I-G-K-L-S-A-I-M-P-D-A-I-R-F-C-F-D-I-C-T-Q-G-T-V-L-E-G-A-T-L-E-I-L-E-I-P-G-L-G-R-C-R-Q-C-G-G-E-I-Y-L-D-K-P-F-G-I-C-N-C-G-S-V-Q-L-D-L-I-T-G-E-E-L-K-I-K-E-I-E-I-E-E-L-C-V"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-E-Q-K-S-Y-V-I-I-D-E-T-G-I-H-A-R-P-A-T-M-L-V-Q-T-A-S-K-F-D-S-D-I-Q-L-E-Y-N-G-K-K-V-N-L-K-S-I-M-G-V-M-S-L-G-V-G-K-D-A-E-I-T-I-Y-A-D-G-S-D-E-T-D-A-I-E-A-I-T-D-I-L-S-K-E-G-L-T-K"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-G-K-L-T-L-L-L-L-A-L-L-V-W-L-Q-Y-S-L-W-F-G-K-N-G-L-H-D-Y-T-R-V-N-D-D-V-T-A-Q-Q-A-T-N-A-K-L-K-A-R-N-D-Q-L-F-A-E-I-D-D-L-N-G-G-Q-E-A-I-E-E-R-A-R-N-E-L-S-M-T-R-P-G-E-T-F-Y-R-L-V-P-D-A-S-K-R-N-Q-A-S-G-Q-Q-Q-N-N-R"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-I-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-N-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-P-V-N-H-H-H-A-S-D-R-P-A-T-L-E-K-T-E-E"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-G-N-N-F-N-A-S-N-A-D-T-D-H-L-P-Q-V-S-I-L-A-Q-Y-I-K-D-L-S-F-E-N-P-N-A-P-A-V-Y-Q-W-Q-T-Q-P-H-I-E-V-Q-F-N-I-G-T-Q-P-M-A-Q-D-V-Y-E-V-A-L-K-V-D-V-S-A-K-A-D-E-G-V-V-F-H-V-E-L-V-Y-N-G-L-F-A-I-K-N-V-P-A-D-Q-I-Q-P-F-L-Y-I-E-A-P-R-I-L-F-P-F-V-R-R-I-L-A-D-S-V-R-D-G-N-F-P-P-L-M-L-E-P-I-D-F-A-A-L-Y-M-Q-Q-T-E-Q-Q-D-M-L-S-N-T-E-P-A-G-Q-A"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-T-I-E-E-R-V-K-K-I-V-V-E-Q-L-G-V-K-E-E-E-V-T-N-S-A-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-E-C-E-I-P-D-E-E-A-E-K-I-T-S-V-Q-Q-A-I-D-Y-V-K-V-H-V-K-S"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-M-K-V-I-P-L-G-E-R-L-L-I-K-P-I-K-E-E-K-K-T-E-G-G-I-V-L-P-D-S-A-K-E-K-P-M-K-A-E-V-V-A-V-G-K-I-E-D-E-E-K-F-D-I-K-V-G-D-K-V-I-F-S-K-Y-A-G-T-E-I-K-I-D-D-E-D-Y-I-I-I-D-V-N-D-I-L-A-K-I-E-E"} +{"text": "### FUNCTION Major structural protein of the hrp pilus, which is a component of the type III secretion system ### SEQUENCE -M-N-I-M-S-S-L-T-N-A-G-R-G-V-V-N-T-V-G-G-A-A-Q-G-I-N-S-V-K-S-S-A-D-R-N-I-A-L-T-K-N-T-G-S-T-D-S-I-D-A-T-R-S-S-I-S-K-G-D-A-K-S-A-E-L-D-G-T-A-N-E-E-N-G-L-L-R-E-T-S-M-L-A-G-F-E-D-K-K-E-A-L-S-N-Q-I-V-A-S-K-I-R-N-S-V-V-Q-F"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-L-C-M-S-A-A-D-I-I-R-E-Q-A-E-Q-H-G-I-A-R-V-T-D-V-W-L-E-V-G-A-L-A-D-V-E-E-S-A-L-H-F-C-F-D-I-A-C-R-D-T-V-A-Q-G-C-T-L-H-I-D-V-I-P-A-Q-A-W-C-W-D-C-S-R-E-A-E-I-M-Q-H-A-G-C-C-P-H-C-G-S-E-R-L-R-I-T-E-G-D-D-L-R-V-K-S-L-E-G-E"} +{"text": "### FUNCTION Involved in the stabilization of the sigma stress factor RpoS ### SEQUENCE -M-E-W-K-V-V-D-T-V-I-S-P-S-T-G-V-S-F-S-C-I-H-S-L-K-N-L-R-L-T-L-W-Y-Q-A-D-V-Y-M-P-P-G-S-I-I-I-P-F-N-K-G-V-L-I-N-D-K-L-Y-P-V-T-V-Y-N-V-T-R-F-N-P-V-L-W-K-S-L-K-E-N-S-H-C-P-G-N-C-N-P-K-S-E-A-C-S-Y-P-F-E-C-L-V-S-V-C-P-F-G-L-T-R-N-I-Q-I-D-N-K-K-V"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-L-T-K-A-E-L-A-D-I-L-V-D-K-V-S-N-V-T-K-N-S-A-K-E-I-V-E-L-F-F-E-E-I-R-S-T-L-A-S-G-E-E-I-K-I-S-G-F-G-N-F-Q-L-R-D-K-P-Q-R-P-G-R-N-P-K-T-G-E-E-V-P-I-T-A-R-R-V-V-T-F-H-A-S-Q-K-L-K-G-M-V-E-H-Y-Y"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-L-L-H-D-R-V-I-V-K-R-K-E-M-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-E-V-I-A-V-G-K-G-R-V-L-E-N-G-N-I-Q-P-L-D-V-K-I-G-D-T-I-I-F-N-D-G-Y-S-V-K-V-E-K-I-D-N-Q-D-V-L-I-M-S-E-S-D-I-L-A-I-V-E-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-K-R-K-E-V-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-E-I-I-A-V-G-K-G-R-V-L-E-N-G-N-T-Q-P-L-D-V-K-I-G-D-T-V-I-F-N-D-G-Y-G-V-K-V-E-K-I-D-N-Q-D-M-L-I-M-S-E-S-D-I-L-A-I-V-E-A"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-I-K-R-Q-E-S-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-T-V-L-A-V-G-N-G-R-I-L-D-N-G-S-V-K-S-L-D-V-K-V-G-D-V-V-I-F-N-E-G-Y-G-A-K-T-E-K-M-D-H-E-E-V-L-I-L-T-E-S-D-I-L-A-I-V-E-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-I-K-R-Q-E-V-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-I-V-T-A-V-G-N-G-R-V-L-D-N-G-E-L-K-A-L-D-V-K-I-G-D-T-V-I-F-S-E-G-Y-G-A-K-I-E-K-I-D-N-E-E-F-L-I-L-T-E-S-D-I-L-A-V-V-E-D"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-L-V-K-R-Q-E-V-E-L-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-T-V-V-A-V-G-K-G-R-I-L-D-N-G-E-T-K-S-L-D-V-K-I-G-D-V-V-I-F-N-E-G-Y-G-A-K-T-E-K-I-D-N-E-E-L-L-I-L-T-E-S-D-I-L-A-I-V-E-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-I-R-P-L-H-D-R-V-I-V-K-R-K-E-A-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-T-V-T-A-V-G-N-G-R-I-L-D-N-G-S-I-K-P-L-D-V-K-V-G-E-T-V-I-F-N-E-G-Y-G-A-K-I-E-K-I-D-N-E-E-L-L-I-L-T-E-S-D-I-L-A-I-V-E-E"} +{"text": "### FUNCTION Involved in the antibiotic teicoplanin susceptibility Inactivation of the tcaRAB operon leads to teicoplanin resistance ### SEQUENCE -M-V-K-H-L-Q-D-H-I-Q-F-L-E-Q-F-I-N-N-V-N-A-L-T-A-K-M-L-K-D-L-Q-N-E-Y-E-I-S-L-E-Q-S-N-V-L-G-M-L-N-K-E-P-L-T-I-S-E-I-T-Q-R-Q-G-V-N-K-A-A-V-S-R-R-I-K-K-L-I-D-A-K-L-V-K-L-D-K-P-N-L-N-I-D-Q-R-L-K-F-I-T-L-T-D-K-G-R-A-Y-L-K-E-R-N-A-I-M-T-D-I-A-Q-D-I-T-N-D-L-N-S-E-D-I-E-N-V-R-Q-V-L-E-V-I-N-H-R-I-K-T-Y-S-N-H-K"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-S-L-P-N-P-A-E-L-I-S-Q-M-A-I-R-L-K-A-H-L-E-H-R-G-I-S-D-P-R-Y-I-G-I-R-T-G-G-V-W-V-A-Q-A-L-L-E-A-L-G-S-Q-S-P-L-G-T-L-D-V-S-F-Y-R-D-D-F-S-Q-N-G-L-H-P-Q-V-R-P-S-A-L-P-F-E-I-E-G-Q-H-L-V-L-I-D-D-V-L-M-S-G-R-T-I-R-A-A-M-N-E-L-F-D-Y-G-R-P-A-S-V-T-L-V-C-L-L-D-L-D-A-A-E-L-P-I-R-P-N-V-V-G-A-T-L-T-L-A-A-H-E-R-V-K-L-S-G-P-S-P-L-Q-L-E-L-Q-D-L-A-L"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-L-R-L-L-L-G-F-D-Y-G-T-K-Q-I-G-V-A-V-G-Q-V-I-T-G-Q-A-R-E-L-C-T-L-K-A-Q-N-G-V-P-D-W-N-Q-V-E-A-L-I-K-E-W-K-P-D-A-V-V-V-G-L-P-L-N-M-D-G-T-P-S-D-M-C-L-R-A-E-K-F-A-R-R-L-N-G-R-Y-N-L-P-F-Y-T-H-D-E-R-L-T-T-F-E-A-K-G-E-R-L-V-R-G-G-Q-K-G-S-Y-R-D-N-P-V-D-A-I-A-A-A-L-L-L-Q-G-W-L-D-A-N-A-A-L-F-E-T"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-I-T-K-E-D-I-L-E-A-V-G-S-L-T-V-M-E-L-N-D-L-V-K-A-F-E-E-K-F-G-V-S-A-A-A-V-A-V-A-G-P-A-G-A-G-A-A-A-A-E-E-K-T-E-F-D-V-V-L-A-S-A-G-D-Q-K-V-G-V-I-K-V-V-R-A-I-T-G-L-G-L-K-E-A-K-D-I-V-D-G-A-P-K-T-L-K-E-G-V-S-K-A-E-A-E-D-I-Q-K-Q-L-E-E-A-G-A-K-V-E-I-K"} +{"text": "### FUNCTION Has a post-transcriptional repressor function in flagellum biogenesis Associates with the 5'-UTR of fljK mRNA and promotes its degradation ### SEQUENCE -M-K-S-T-L-R-I-S-L-K-S-G-E-R-I-F-V-N-G-A-V-L-R-V-D-R-K-V-A-I-E-F-L-N-D-V-T-F-L-L-E-N-H-V-L-Q-P-E-D-A-T-T-P-L-R-Q-L-Y-F-I-A-Q-M-I-L-I-N-P-E-G-A-D-Q-S-T-A-M-F-R-K-S-I-V-M-L-L-N-C-F-K-H-D-E-V-L-A-E-L-K-R-I-D-G-L-V-T-Q-G-R-A-F-E-A-L-K-A-I-R-G-L-Y-P-I-E-D-Q-I-L-N-A-Q-E-L-T-P-A-T-V-E-Q-I-R-K-E-I-A-P-W-R"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-V-L-T-R-K-V-G-E-S-L-L-I-G-D-D-I-E-I-T-V-L-S-V-R-G-N-Q-V-K-L-G-V-N-A-P-K-N-I-V-V-H-R-E-E-I-Y-H-Q-I-K-A-L-A-D-N-I-P-E-S-V"} +{"text": "### FUNCTION Transcription regulator that can specifically activate or repress expression of target genes ### SEQUENCE -M-E-S-T-L-G-S-D-L-S-R-L-V-R-V-W-R-A-L-I-D-Q-R-L-K-P-L-E-L-T-Q-T-H-W-V-T-L-Y-N-I-H-R-L-P-P-D-Q-S-Q-I-Q-L-A-K-A-I-G-I-E-Q-P-S-L-V-R-T-L-D-Q-L-E-D-K-G-L-I-T-R-H-I-C-A-N-D-R-R-A-K-R-I-K-L-T-D-D-A-E-P-V-I-K-E-V-T-G-V-I-S-L-T-R-S-E-I-L-D-G-I-S-T-D-E-I-A-L-L-T-N-L-V-E-R-L-E-Q-N-I-I-H-L-Q-N-K"} +{"text": "### FUNCTION Dephosphorylates Wzc Required for the extracellular polysaccharide colanic acid synthesis Probably involved in the export of colanic acid from the cell to medium Involved in protection of cells against contact-dependent growth inhibition ### SEQUENCE -M-F-N-K-I-L-V-V-C-V-G-N-V-C-R-S-P-T-A-E-R-L-L-K-R-F-H-P-S-L-T-V-A-S-A-G-L-G-A-L-V-G-K-G-A-D-P-A-A-A-S-V-A-S-A-H-D-L-S-L-E-N-H-C-A-R-Q-I-S-A-R-L-C-R-E-Y-D-L-I-L-T-M-E-K-R-H-I-A-A-L-C-D-I-A-P-E-M-R-G-K-V-M-L-F-G-H-W-D-S-E-R-E-I-P-D-P-Y-R-K-S-R-D-A-F-E-A-V-Y-T-L-L-E-R-S-A-R-Q-W-A-Q-A-L-N-A-E-Q-G-K-P"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-G-S-K-I-P-L-P-Q-Y-E-T-K-G-S-A-G-L-D-L-R-A-C-L-D-S-N-L-S-L-Q-A-G-T-S-Q-L-I-P-I-G-F-A-M-Y-L-E-D-P-G-L-A-A-M-V-I-P-R-S-G-L-G-S-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-E-L-M-V-P-A-W-N-R-S-D-T-D-F-E-I-N-P-G-D-R-I-A-Q-M-I-I-V-P-V-I-Q-A-D-F-E-I-V-D-E-F-N-E-T-Q-R-G-E-K-G-F-G-S-S-G-I-N"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA Neutralized by coexpression with cognate antitoxin MazE ### SEQUENCE -M-I-R-R-G-D-V-Y-L-A-D-L-S-P-V-Q-G-S-E-Q-G-G-V-R-P-V-V-I-I-Q-N-D-T-G-N-K-Y-S-P-T-V-I-V-A-A-I-T-D-G-I-N-K-A-K-I-P-T-H-V-E-I-E-K-K-K-Y-K-L-D-K-D-S-V-I-L-L-E-Q-I-R-T-L-D-K-K-R-L-K-E-K-L-T-F-L-S-E-S-K-M-I-E-V-D-N-A-L-D-I-S-L-G-L-N-N-F-D-H-H-K-S"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-F-I-I-A-G-L-G-N-P-G-Q-E-Y-E-N-T-R-H-N-A-G-F-M-V-V-D-E-L-A-K-K-H-G-I-L-I-T-K-R-K-F-K-S-L-V-G-E-G-E-I-L-G-V-K-V-L-L-L-K-P-Q-T-Y-M-N-L-S-G-T-A-V-Q-E-A-V-S-F-Y-K-L-P-L-S-R-L-V-V-V-Y-D-D-L-D-L-P-L-G-K-I-R-L-R-L-K-G-S-A-G-G-H-R-G-M-G-S-I-I-S-C-L-G-S-E-E-I-P-R-L-K-I-G-I-G-R-P-A-V-G-D-V-K-D-Y-V-L-Q-P-F-T-G-A-E-R-E-I-L-E-P-T-L-K-L-A-A-E-A-I-T-V-A-L-T-E-G-F-N-K-A-M-T-D-F-N-R-G-G"} +{"text": "### FUNCTION Involved in the temperature-dependent positive control of flagellum-driven swimming motility and cellular aggregation Regulates fliC expression by directly interacting with fliC promoter ### SEQUENCE -M-A-L-R-N-K-A-F-H-Q-L-R-Q-L-F-Q-Q-H-T-A-R-W-Q-H-E-L-P-D-L-T-K-P-Q-Y-A-V-M-R-A-I-A-D-K-P-G-I-E-Q-V-A-L-I-E-A-A-V-S-T-K-A-T-L-A-E-M-L-A-R-M-E-N-R-G-L-V-R-R-E-H-D-P-A-D-K-R-R-R-F-V-W-L-T-A-E-G-E-K-I-L-A-A-A-I-P-I-G-D-S-V-D-E-E-F-L-G-R-L-S-G-E-E-Q-E-L-F-M-Q-L-V-R-K-M-M-N-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-V-I-L-L-E-R-I-S-K-L-G-Q-M-G-E-T-V-K-V-R-D-G-F-A-R-N-Y-L-L-P-L-G-K-A-L-R-A-N-A-A-N-K-T-R-F-E-A-E-R-A-T-L-E-A-R-N-L-E-R-K-S-E-A-Q-K-V-A-D-V-L-D-G-K-S-F-I-V-V-R-S-A-G-E-T-G-Q-L-Y-G-S-V-A-A-R-D-V-V-E-I-L-G-A-E-G-F-N-I-G-R-N-Q-V-H-L-N-T-P-I-K-S-I-G-L-H-K-V-E-L-Q-L-H-A-E-V-E-I-H-V-E-L-N-V-A-R-S-A-E-E-A-E-R-Q-A-K-G-E-E-L-T-S-V-D-A-I-Y-G-V-D-E-D-A-L-R-P-E-D-F-F-D-P-E-A-D-G-V-D-E-D-E-A"} +{"text": "### FUNCTION Catalyzes the interconversion of L-alanine and D-alanine May also act on other amino acids ### SEQUENCE -N-S-A-A-I-F-N-F-S-Y-E-R-Y-D-W-V-R-P-G-I-M-L-Y-G-I-S-P-F-A-D-K-N-G-V-D-L-E-L-Q-P-V-M-H-V-V-S-R-L-I-S-V-K-Q-L-R-Q-G-E-S-V-G-Y-G-A-T-W-Q-C-P-E-D-M-Q-V-G-I-L-S-L-G-Y-G-D-G-Y-P-R-L-A-A-S-G-T-P-F-L-V-R-G-Q-R-C-A-L-I-G-R-V-S-M-D-M-I-A-I-D-L-R-R-C-P-D-A-G-V-G-E-A-V-T-V-W-G-Q-D-L-P-V-E-E-I-A-R-H-V-G-T-I-A-Y-E-L-V-C-N-M-P-L-R-A-P-Y-I-W-Q-E"} +{"text": "### FUNCTION Required for coenzyme pyrroloquinoline quinone ### SEQUENCE -M-W-T-K-P-S-Y-T-D-L-R-I-G-F-E-V-T-L-Y-F-A-N-R"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-E-Q-K-I-R-V-K-L-K-A-F-D-I-E-L-I-D-Q-S-A-Q-S-I-V-A-S-V-K-K-T-G-A-R-V-S-G-P-I-P-L-P-T-S-I-R-K-V-T-V-I-R-S-P-H-V-N-I-K-S-R-E-Q-F-E-M-R-V-Y-K-R-L-I-D-I-F-D-V-T-P-Q-T-T-E-S-L-K-K-L-A-L-P-A-G-V-D-V-Q-L-K"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-M-G-I-L-D-E-L-R-G-L-S-A-A-E-D-F-F-R-T-L-G-V-K-Y-D-A-E-V-L-N-V-A-R-L-H-I-L-R-R-M-G-T-Y-L-S-Q-A-E-L-E-P-D-E-D-A-A-R-A-Q-C-R-A-Q-L-Q-R-A-Y-D-D-F-T-R-S-T-P-I-A-E-R-V-F-K-V-H-R-D-A-V-R-P-S-G-G-F-V-S-L-S-E-L-T-Q-D-G-T"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-R-F-T-Q-V-I-N-S-E-G-R-D-N-F-T-D-R-E-N-C-L-I-V-C-L-T-M-D-E-R-T-K-S-R-L-K-V-C-L-N-N-G-D-E-A-G-L-F-L-P-R-G-T-V-L-K-E-G-D-L-L-Q-A-E-T-G-E-I-A-L-V-E-A-A-E-E-V-V-S-T-A-F-T-D-D-L-L-L-L-A-K-A-C-Y-H-L-G-N-R-H-V-P-L-Q-V-E-L-G-W-C-R-Y-L-H-D-H-V-L-D-D-M-V-K-G-L-G-L-G-V-R-V-E-R-A-K-Y-Q-P-E-P-G-A-Y-G-G-S-I-S-G-A-S-H-G-H-H-H-H"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-N-D-I-G-A-L-E-L-V-T-L-V-V-L-A-V-L-V-F-G-P-D-K-L-P-K-V-I-Q-D-V-T-R-T-I-R-K-I-R-E-F-S-D-S-A-K-Q-D-I-R-Q-E-L-G-P-E-F-K-D-F-E-F-E-D-L-N-P-K-T-F-I-R-K-Q-L-D-N-E-E-L-G-L-K-E-I-R-N-G-F-D-L-K-K-E-M-A-E-V-T-D-A-V-H-G-R-D-A-E-S-S-S-S-G-S-S-S-G-S-S-S-A-A-S-G-N-G-R-V-D-M-S-K-K-P-E-K-P-E-K-P-G-K-T-D-K-P-A-A-D-D-R-P-P-F-D-M-D-A-T"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-T-S-E-V-E-Q-P-T-A-M-S-E-A-L-G-Y-E-Q-A-R-D-E-L-I-E-V-V-R-R-L-E-A-G-G-T-T-L-E-E-S-L-A-L-W-E-R-G-E-E-L-A-E-V-C-R-R-R-L-D-G-A-R-A-R-L-D-A-A-L-A-E-E-A-D-P-E-D-G-A-S-G-A-D-G-G-G-A"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-W-L-L-V-V-A-G-G-M-I-G-A-P-L-R-Y-L-T-D-R-A-V-Q-S-R-H-D-S-V-F-P-W-G-T-F-T-V-N-V-I-G-S-V-V-L-G-L-L-T-G-A-A-L-A-G-A-V-G-S-D-L-R-L-L-L-G-T-G-L-C-G-A-L-T-T-Y-S-T-F-S-Y-E-T-L-R-L-T-E-T-G-A-R-L-H-A-A-V-N-V-G-G-S-V-A-A-G-L-V-A-A-F-A-G-V-T-L-A-D-A-L-W-A"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-T-V-P-R-T-G-R-P-G-G-I-R-A-A-A-P-S-R-S-G-W-R-T-Q-A-P-V-V-A-V-V-A-L-G-G-G-T-G-A-A-A-R-Y-A-A-S-L-W-W-P-T-P-A-G-G-F-P-W-T-T-F-G-V-N-A-V-G-C-A-V-I-G-V-F-M-V-V-I-T-E-V-R-P-A-H-R-L-V-R-P-F-F-G-T-G-V-L-G-G-F-T-T-F-S-T-Y-A-V-D-S-R-S-L-F-A-D-G-R-L-P-T-G-L-A-Y-L-A-A-T-P-L-A-A-L-T-A-V-W-L-A-A-W-A-A-R-R-V-L-K-W-R-Q-S"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-Y-G-I-G-I-D-I-T-N-I-D-R-F-K-A-L-H-N-P-T-S-F-I-K-K-V-L-T-D-K-E-Q-A-E-L-A-G-K-S-G-Q-R-A-Y-E-F-L-A-G-H-F-S-V-K-E-S-Y-S-K-A-Y-G-T-G-L-G-K-K-L-N-F-Q-D-I-E-V-E-Y-D-D-N-G-R-P-V-I-S-N-H-P-F-A-G-V-A-H-V-S-I-S-H-S-K-H-H-V-V-T-Q-V-I-L-E-G-D"} +{"text": "### FUNCTION Major structure protein of the hrp pilus, which is a component of the type III secretion system ### SEQUENCE -M-G-L-G-G-P-L-S-S-A-T-S-F-A-S-K-T-L-E-G-A-M-S-D-S-M-A-E-S-A-V-A-Q-A-A-K-M-K-I-D-T-Q-N-S-I-L-D-G-K-M-D-S-A-T-K-E-I-N-S-G-H-N-A-A-K-A-I-Q-F"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-K-T-G-G-K-Q-Y-K-V-A-V-G-E-K-L-K-V-E-Q-I-P-A-D-I-D-A-E-I-T-L-D-Q-V-L-A-V-G-E-G-E-S-I-Q-F-G-T-P-L-V-S-G-A-S-V-K-A-T-V-V-S-H-G-R-H-A-K-V-T-I-F-K-M-R-R-R-K-H-Y-Q-K-H-G-G-H-R-Q-N-Y-T-E-L-R-I-D-A-I-N-A"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-Q-V-V-Y-N-F-S-Q-P-G-L-Q-W-K-Q-S-D-H-L-R-S-L-M-T-V-T-S-R-D-W-L-L-D-R-G-S-L-T-R-R-L-R-V-L-S-D-D-D-L-E-V-V-P-L-R-E-E-V-G-V-I-L-P-H-E-A-D-V-L-G-L-Q-L-G-A-I-G-G-V-R-E-V-Y-L-V-G-F-G-R-P-W-V-F-A-R-S-I-I-V-N-S-G-S-I-E-E-G-S-A-L-L-Q-L-G-N-M-P-L-G-D-L-L-F-G-D-G-S-F-Q-R-S-E-I-E-V-C-R-Y-H-D-A-C-N-A-S-A-R-S-T-Y-P-L-W-A-R-R-S-V-F-K-R-E-K-M-H-V-L-V-Q-E-M-F-L-P-A-L-W-E-E-M-S"} +{"text": "### FUNCTION Provides oxygen to the bacteroids This role is essential for symbiotic nitrogen fixation ### SEQUENCE -M-G-F-T-A-Q-Q-E-A-L-V-G-S-S-Y-E-T-F-K-K-N-L-P-T-N-S-V-L-F-Y-T-V-I-L-E-I-A-P-T-A-K-D-M-F-S-F-L-K-E-S-G-P-K-H-S-P-Q-L-Q-A-H-A-E-K-V-F-A-L-T-R-D-A-A-T-Q-L-V-A-K-G-E-V-T-L-A-D-A-S-L-G-A-V-H-V-Q-K-A-V-T-D-P-H-F-V-V-V-K-E-A-L-L-Q-T-V-K-E-A-V-G-A-D-E-W-S-D-D-L-S-T-A-W-E-G-A-Y-D-G-L-A-T-A-I-K-K-A-M-G"} +{"text": "### FUNCTION Involved in the infection process during the plant-rhizobium interaction ### SEQUENCE -M-A-S-F-F-L-Y-S-L-G-L-V-F-L-S-A-L-T-L-V-P-L-G-L-A-D-K-S-P-S-H-N-M-P-P-N-P-I-Y-T-T-P-I-H-K-N-P-T-N-T-P-V-Y-N-P-P-I-Y-K-P-P-P-T-Y-K-P-P-I-K-K-Q-P-I-N-K-S-P-N-K-K-P-L-L-L-K-P-P-L-P-K-P-P-H-K-E-P-P-S-R-K-R-P-I-N-T-P-P-D-K-K-P-P-L-L-K-P-P-F-P-K-P-P-Q-K-K-P-P-S-R-K-R-P-I-N-T-P-P-N-K-K-P-P-L-P-K-P-P-V-N-K-P-P-H-K-K-P-S-N-K-R-P-P-P-Y-G-N-Q-P-P-P-S-I-H-F"} +{"text": "### FUNCTION Binds directly to 26S ribosomal RNA ### SEQUENCE -M-P-P-K-L-D-P-S-Q-I-V-D-V-Y-V-R-V-T-G-G-E-V-G-A-A-S-S-L-A-P-K-I-G-P-L-G-L-A-P-K-K-I-G-E-D-I-A-K-E-T-A-K-E-W-K-G-L-R-V-T-V-K-L-T-V-Q-N-R-Q-A-K-V-T-V-V-P-S-A-A-A-L-V-I-K-A-L-K-E-P-E-R-D-R-K-K-V-K-N-I-K-H-N-G-N-I-S-F-D-D-V-I-E-I-A-K-I-M-R-P-R-S-I-A-K-E-L-S-G-T-V-K-E-I-L-G-T-C-V-S-V-G-C-T-V-D-G-K-D-P-K-D-L-Q-E-E-I-N-S-G-D-I-D-I-P-N-E"} +{"text": "### FUNCTION Potential transcription factor that plays a central role during developmental processes ### SEQUENCE -M-S-S-R-G-F-N-I-K-A-R-G-L-C-N-N-N-N-G-G-G-G-T-G-A-K-C-G-R-W-N-P-T-V-E-Q-V-K-L-L-T-D-L-F-K-A-G-L-R-T-P-S-T-D-Q-I-Q-K-I-S-M-E-L-S-F-Y-G-K-I-E-S-K-N-V-F-Y-W-F-Q-N-H-K-A-R-E-R-Q-K-C-R-K-I-S-T-V-K-F-D-H-R-Q-D-T-D-L-S-K-P-R-R-D-N-V-R-R-H-Q-L-P-A-K-G"} +{"text": "### FUNCTION Probably acts as a transcriptional activator Binds to the GCC-box pathogenesis-related promoter element May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways ### SEQUENCE -M-D-Y-S-E-N-V-Q-N-K-N-F-T-P-I-S-Q-P-P-N-L-T-R-D-Q-E-H-A-I-M-V-S-T-L-R-Q-V-I-S-N-T-G-G-D-T-S-S-S-H-Y-I-A-A-S-E-A-L-P-P-S-D-A-G-P-C-P-L-C-G-V-T-S-C-Y-G-C-A-F-P-Q-H-E-E-I-K-Q-E-K-K-H-K-G-V-R-K-K-P-S-G-K-W-S-A-E-I-W-D-P-S-T-R-T-R-R-W-L-G-T-F-P-T-A-E-M-A-A-D-A-Y-D-E-A-A-A-A-L-V-E-K-R-S-A-R-R-G-S-K-K-G-E-G-S-I-H-Q-E-V-G-G-G-D-D"} +{"text": "### FUNCTION Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs ### SEQUENCE -M-L-N-L-D-F-T-H-K-T-T-Q-A-T-P-R-L-H-A-V-A-T-E-F-L-R-V-S-N-D-V-A-E-L-H-K-L-S-S-K-L-T-S-D-P-Y-L-F-V-E-F-V-K-T-I-R-G-F-L-S-V-Q-T-A-L-G-L-S-G-E-I-D-T-V-F-L-Q-V-I-K-G-W-F-P-D-L-I-T-E-T-F-S-F-L-I-V-V-R-I-I-N-L-F-N-K-R-A-N-S-K-V-Y-P-D-I-L-R-R-I-G-N-N-A-L-Y-L-T-R-N-P-L-R-G-I-C-L-V-E-K-A-I-N-V-R-D-P-D-C-T-V-F-I-A-L-K-L-H-S-H-Y-V-E-L-S-F-E-E-L-G-S-N-I-V-E-K-L-L-S-V-G-E-S-G-I-C-G-V"} +{"text": "### FUNCTION Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light ### SEQUENCE -M-E-G-E-T-A-A-K-A-A-A-S-S-S-S-S-P-S-R-Y-E-S-Q-K-R-R-D-W-N-T-F-L-Q-Y-L-R-N-H-K-P-P-L-N-L-S-R-C-S-G-A-H-V-L-E-F-L-K-Y-L-D-Q-F-G-K-T-K-V-H-A-T-A-C-P-F-F-G-Q-P-N-P-P-S-Q-C-T-C-P-L-K-Q-A-W-G-S-L-D-A-L-I-G-R-L-R-A-A-F-E-E-I-G-G-G-L-P-E-S-N-P-F-A-A-K-A-V-R-I-Y-L-K-E-V-R-Q-T-Q-A-K-A-R-G-I-P-Y-D-K-K-K-R-K-R-P-H-T-D-T-A-T-P-I-A-G-D-G-D-D-A-E-G-S-G-G-A-A-L-V-V-T-A-A-T-T-V"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-A-G-R-L-S-G-V-A-S-R-I-M-G-G-N-G-V-V-A-R-S-V-G-S-S-L-R-Q-R-A-G-M-G-L-P-V-G-K-H-I-V-P-D-K-P-L-S-V-N-D-E-L-M-W-D-N-G-T-A-F-P-E-P-C-I-D-R-I-A-D-T-V-G-K-Y-E-A-L-A-W-L-S-G-G-L-G-F-F-V-G-L-G-L-L-A-V-L-N-D-K-A-S-K-V-P-F-T-P-R-V-Y-P-Y-D-N-L-R-V-E-L-G-G-E-P"} +{"text": "### FUNCTION Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters ### SEQUENCE -M-E-N-N-N-N-N-H-Q-Q-P-P-K-D-N-E-Q-L-K-S-F-W-S-K-G-M-E-G-D-L-N-V-K-N-H-E-F-P-I-S-R-I-K-R-I-M-K-F-D-P-D-V-S-M-I-A-A-E-A-P-N-L-L-S-K-A-C-E-M-F-V-M-D-L-T-M-R-S-W-L-H-A-Q-E-S-N-R-L-T-I-R-K-S-D-V-D-A-V-V-S-Q-T-V-I-F-D-F-L-R-D-D-V-P-K-D-E-G-E-P-V-V-A-A-A-D-P-V-D-D-V-A-D-H-V-A-V-P-D-L-N-N-E-E-L-P-P-G-T-V-I-G-T-P-V-C-Y-G-L-G-I-H-A-P-H-P-Q-M-P-G-A-W-T-E-E-D-A-T-G-A-N-G-G-N-G-G-N"} +{"text": "### FUNCTION Involved in the transport of copper ### SEQUENCE -M-N-G-M-S-G-S-S-P-A-A-P-A-P-S-P-S-S-F-F-Q-H-R-H-R-H-G-G-M-M-H-M-T-F-F-W-G-K-T-T-E-V-L-F-D-G-W-P-G-T-S-L-K-M-Y-W-V-C-L-A-V-I-F-V-I-S-A-F-S-E-C-L-S-R-C-G-F-M-K-S-G-P-A-S-L-G-G-G-L-L-Q-T-A-V-Y-T-V-R-A-A-L-S-Y-L-V-M-L-A-V-M-S-F-N-G-G-V-F-V-A-A-M-A-G-F-G-L-G-F-M-I-F-G-S-R-A-F-R-A-T-S-S-N-S-H-T-E-V-Q-S-H-C"} +{"text": "### FUNCTION May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments ### SEQUENCE -M-T-P-S-P-P-P-I-T-Y-I-S-I-P-L-P-T-N-D-V-V-S-R-S-I-H-N-L-T-T-A-I-S-S-H-R-P-W-S-E-L-I-F-S-G-D-F-S-L-P-E-S-F-S-S-L-L-L-R-S-K-T-N-F-N-Y-F-F-V-N-Y-T-I-I-V-S-T-C-A-A-F-A-L-I-T-A-S-P-V-A-L-I-V-V-G-A-I-I-A-L-W-L-I-F-H-F-F-R-E-D-P-L-I-L-W-S-F-Q-V-G-D-R-T-V-L-L-F-L-V-L-A-S-V-W-A-I-W-F-T-N-S-A-V-N-L-A-V-G-V-S-V-G-L-L-L-C-I-I-H-A-V-F-R-N-S-D-E-L-F-L-E-E-D-D-A-I-N-G-G-L-I-G-S-N-L-R"} +{"text": "### FUNCTION Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism ### SEQUENCE -M-S-K-L-I-L-I-L-T-A-Q-I-L-L-L-T-A-T-A-L-A-G-K-N-G-E-D-F-A-R-T-I-N-R-K-H-L-G-L-G-K-K-E-K-L-T-H-L-R-V-Y-W-H-D-I-V-T-G-R-N-P-S-S-I-R-I-Q-G-P-V-A-K-Y-S-S-S-S-Y-F-G-S-I-T-M-I-D-N-A-L-T-L-D-V-P-I-N-S-T-V-V-G-Q-A-Q-G-M-Y-V-G-A-A-Q-K-E-I-G-L-L-M-A-M-N-L-A-F-K-T-G-K-Y-N-G-S-T-I-T-I-L-G-R-N-T-V-M-S-K-V-R-E-M-P-V-V-G-G-S-G-M-F-R-F-A-R-G-Y-V-E-A-R-T-K-L-F-D-M-K-T-G-D-A-T-V-E-S-N-C-Y-I-L-H-Y"} +{"text": "### FUNCTION Elicitor of plant defense ### SEQUENCE -M-E-R-G-V-S-Y-Y-L-W-I-P-F-K-F-I-H-Q-T-F-G-S-L-L-L-K-L-L-G-L-R-S-P-S-D-H-S-F-P-E-D-G-E-E-E-V-K-V-V-E-V-S-S-R-G-L-P-G-K-K-N-V-L-K-K-S-R-E-S-S-G-K-P-G-G-T-N-K-K-P-F"} +{"text": "### FUNCTION Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism ### SEQUENCE -M-A-K-R-F-L-L-L-L-P-L-L-S-S-I-L-L-L-A-V-S-V-T-A-Y-S-T-T-T-P-Y-Q-G-Y-K-P-E-K-F-T-H-L-H-F-Y-F-H-D-V-I-S-G-D-K-P-T-A-V-K-V-A-E-A-R-P-T-T-T-L-N-V-K-F-G-V-I-M-I-A-D-D-P-L-T-E-G-P-D-P-S-S-K-E-V-G-R-A-Q-G-M-Y-A-S-T-A-M-K-D-I-V-F-T-M-V-F-N-Y-V-F-T-A-G-E-F-N-G-S-T-I-A-V-Y-G-R-N-D-I-F-S-K-V-R-E-L-P-I-I-G-G-T-G-A-F-R-F-A-R-G-Y-A-L-P-K-T-Y-K-I-V-G-L-D-A-V-V-E-Y-N-V-F-I-W-H"} +{"text": "### FUNCTION Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism ### SEQUENCE -M-A-K-R-F-L-L-L-L-P-L-L-S-T-I-L-L-L-S-V-S-V-T-E-S-E-A-Y-S-T-T-K-P-C-Q-G-Y-K-P-D-K-F-T-H-L-H-F-Y-F-H-D-V-I-S-G-D-K-P-T-A-V-K-V-A-E-A-R-R-T-N-S-S-N-V-N-F-G-V-I-M-I-A-D-D-P-L-T-E-G-P-D-P-S-S-K-E-V-G-R-A-Q-G-M-Y-A-L-T-A-M-K-N-I-S-F-T-M-V-F-N-L-A-F-T-A-G-E-F-N-G-S-T-V-A-M-Y-G-R-N-E-I-F-S-K-V-R-E-M-P-I-I-G-G-T-G-A-F-R-F-A-R-G-Y-A-Q-A-K-T-Y-K-V-V-G-L-D-A-V-V-E-Y-N-V-F-I-W-H"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-A-W-R-G-S-I-S-K-S-M-K-E-L-R-I-L-L-C-Q-S-S-P-A-S-A-P-T-R-T-F-V-E-K-N-Y-K-D-L-K-S-L-N-P-K-L-P-I-L-I-R-E-C-S-G-V-Q-P-Q-M-W-A-R-Y-D-M-G-V-E-R-C-V-N-L-D-G-L-T-E-P-Q-I-L-K-A-L-E-N-L-V-K-S-G-A-T-K-A"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-T-R-S-F-S-P-V-V-S-L-F-L-L-L-L-Q-T-I-C-S-A-T-V-E-N-A-A-D-C-A-A-V-G-T-L-I-S-S-C-T-E-F-V-N-Y-G-Y-P-D-P-I-P-G-S-S-C-C-D-A-M-T-V-I-G-T-Y-S-D-S-S-E-K-R-K-W-L-C-N-C-F-M-D-L-I-N-V-Y-N-S-N-A-T-A-I-S-T-L-S-G-F-C-G-V-V-L-G-F-T-I-D-P-N-T-D-C-N-F-I-Q"} +{"text": "### FUNCTION May form complexes with phosphorylated ligands by interfering with kinases and their effectors ### SEQUENCE -M-S-R-E-I-E-P-L-I-V-G-R-V-I-G-D-V-L-E-M-F-N-P-S-V-T-M-R-V-T-F-N-S-N-T-I-V-S-N-G-H-E-L-A-P-S-L-L-L-S-K-P-R-V-E-I-G-G-Q-D-L-R-S-F-F-T-L-I-M-M-D-P-D-A-P-S-P-S-N-P-Y-M-R-E-Y-L-H-W-M-V-T-D-I-P-G-T-T-D-A-S-F-G-R-E-I-V-R-Y-E-T-P-K-P-V-A-G-I-H-R-Y-V-F-A-L-F-K-Q-R-G-R-Q-A-V-K-A-A-P-E-T-R-E-C-F-N-T-N-A-F-S-S-Y-F-G-L-S-Q-P-V-A-A-V-Y-F-N-A-Q-R-E-T-A-P-R-R-R-P-S-Y"} +{"text": "### FUNCTION Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters ### SEQUENCE -M-L-D-H-S-E-K-V-L-L-V-D-S-E-T-M-K-T-R-A-E-D-M-I-E-Q-N-N-T-S-V-N-D-K-K-K-T-C-A-D-C-G-T-S-K-T-P-L-W-R-G-G-P-V-G-P-K-S-L-C-N-A-C-G-I-R-N-R-K-K-R-R-G-G-T-E-D-N-K-K-L-K-K-S-S-S-G-G-G-N-R-K-F-G-E-S-L-K-Q-S-L-M-D-L-G-I-R-K-R-S-T-V-E-K-Q-R-Q-K-L-G-E-E-E-Q-A-A-V-L-L-M-A-L-S-Y-G-S-V-Y-A"} +{"text": "### FUNCTION Functions as positive effectors of cell expansion through modulation of auxin transport ### SEQUENCE -M-A-L-V-R-S-L-L-V-A-K-K-I-L-S-R-S-A-A-A-V-S-A-P-P-K-G-F-L-A-V-Y-V-G-E-S-Q-K-K-R-Y-L-V-P-L-S-Y-L-N-Q-P-S-F-Q-A-L-L-S-K-S-E-E-E-F-G-F-D-H-P-M-G-G-L-T-I-P-C-P-E-D-T-F-I-N-V-T-S-R-L-H"} +{"text": "### FUNCTION Functions as positive effectors of cell expansion through modulation of auxin transport ### SEQUENCE -M-A-L-V-R-S-L-L-G-A-K-K-I-L-S-R-S-T-A-A-V-S-A-A-P-K-G-F-L-A-V-Y-V-G-E-S-Q-K-K-R-Y-L-V-P-L-S-Y-L-N-Q-P-S-F-Q-A-L-L-S-K-S-E-D-E-F-G-F-D-H-P-M-G-G-L-T-I-P-C-H-E-D-T-F-I-N-V-T-S-R-L-Q"} +{"text": "### FUNCTION Functions as positive effectors of cell expansion through modulation of auxin transport ### SEQUENCE -M-A-L-V-R-S-L-L-G-A-K-K-I-L-S-R-S-T-A-S-A-A-P-K-G-F-L-A-V-Y-V-G-E-S-Q-K-K-R-Y-L-V-P-L-S-Y-L-S-Q-P-S-F-Q-A-L-L-S-K-S-E-E-E-F-G-F-D-H-P-M-G-G-L-T-I-P-C-P-E-D-T-F-I-N-V-T-S-R-L-Q"} +{"text": "### FUNCTION Functions as positive effectors of cell expansion through modulation of auxin transport ### SEQUENCE -M-A-F-V-R-S-L-L-G-A-K-K-I-L-S-R-S-T-T-A-A-S-A-A-P-K-G-F-L-A-V-Y-V-G-E-S-Q-K-K-R-Y-L-V-P-I-S-Y-L-N-Q-P-S-F-Q-A-L-L-S-K-S-E-E-E-F-G-F-D-H-P-M-G-G-L-T-I-P-C-P-E-D-T-F-I-N-V-T-S-R-F-Q-R"} +{"text": "### FUNCTION LEA proteins are late embryonic proteins abundant in higher plant seed embryos The function of those proteins is not known ### SEQUENCE -M-M-F-G-F-G-L-L-K-Q-Y-A-G-T-T-E-Q-I-S-T-A-A-E-A-L-V-G-R-S-T-T-L-T-E-A-L-K-A-A-A-I-N-V-G-R-K-P-V-E-T-T-D-L-A-A-I-K-E-V-E-A-R-A-I-G-G-D-I-E-S-D-G-G-V-T-A-V-A-S-K-A-V-A-R-N-Q-K-I-G-E-D-N-E-K-T-N-L-G-D-V-I-A-E-I-D-V-K-V-T-R-D-R-E-V-T-S-E-D-A-E-A-V-I-R-A-E-L-N-H-S-P-F-N-N-I-I-P-G-G-V-A-E-S-V-T-A-A-Y-K-L-N-C-N-P-C-N-V-S-L"} +{"text": "### FUNCTION LEA proteins are late embryonic proteins abundant in higher plant seed embryos The function of those proteins is not known ### SEQUENCE -M-G-S-S-K-D-S-A-S-V-T-N-I-S-V-E-E-H-F-S-V-S-Q-S-S-P-G-G-Q-F-V-G-P-T-E-E-I-S-T-A-A-E-A-L-I-G-R-S-T-T-L-T-E-A-L-K-A-A-S-M-N-V-G-H-K-P-V-E-T-T-D-V-A-A-I-K-E-V-E-T-R-A-I-G-G-D-I-E-S-E-G-G-V-T-A-V-A-S-K-A-V-A-R-N-Q-K-I-G-K-D-N-E-K-T-N-L-G-D-V-I-A-E-I-D-V-K-V-T-R-D-R-E-V-T-S-E-D-A-E-A-V-I-R-A-E-L-N-H-S-P-F-N-N-I-I-P-G-G-V-A-E-S-V-A-A-A-Y-K-L-N-H-D-P-S-S-L"} +{"text": "### FUNCTION Required for ribosome biogenesis Part of a complex which catalyzes pseudouridylation of rRNA This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 Pseudouridine ### SEQUENCE -M-R-P-P-R-G-G-G-S-F-R-G-R-G-G-R-D-N-G-G-R-G-R-G-R-G-R-G-R-G-R-F-G-G-G-N-Y-D-E-G-P-P-S-E-V-V-E-V-A-T-F-L-H-A-C-E-G-D-A-V-F-K-L-S-N-V-K-I-P-H-F-N-A-P-I-Y-L-Q-N-K-T-Q-I-G-R-V-D-E-I-F-G-P-I-N-E-S-L-F-S-I-K-M-R-E-G-I-V-A-T-S-Y-S-Q-G-D-K-F-F-I-S-P-E-K-L-L-P-L-S-R-F-L-P-Q-P-K-G-Q-S-G-G-R-G-E-G-R-V-P-P-R-G-R-G-P-P-R-G-R-G-N-F-R-G-R-G-A-P-R-G-A-S-R-G-F-Q-P-R-G-G-P-R-G-G-F-R-G-R-G-R-A"} +{"text": "### FUNCTION Functions as positive effectors of cell expansion through modulation of auxin transport ### SEQUENCE -M-A-F-V-R-S-L-L-G-A-K-K-I-L-S-R-S-T-G-A-G-S-A-A-P-K-G-F-L-A-V-Y-V-G-E-S-Q-K-K-R-Y-L-V-P-V-S-Y-L-N-Q-P-S-F-Q-A-L-L-S-K-S-E-E-E-F-G-F-D-H-P-M-G-G-L-T-I-P-C-P-E-D-T-F-I-N-V-T-S-R-L-Q"} +{"text": "### FUNCTION Core component of nucleosome Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling ### SEQUENCE -M-A-R-T-K-Q-T-A-R-I-S-T-G-G-K-A-P-R-K-Q-L-A-P-K-A-A-R-Q-S-A-P-A-T-G-G-V-K-K-P-H-R-F-R-P-G-T-V-A-L-R-D-I-R-K-Y-Q-K-S-T-E-I-L-I-R-K-L-P-F-Q-R-L-V-R-E-I-A-Q-D-F-K-T-D-L-R-F-Q-S-S-A-V-A-A-L-Q-E-A-A-E-A-Y-L-V-G-L-F-E-D-T-N-L-C-A-I-H-A-K-R-V-T-I-M-P-K-E-I-Q-L-A-R-R-I-R-G-E-R-A-R-G-E"} +{"text": "### FUNCTION Involved in cytokinin-mediated development ### SEQUENCE -M-D-K-E-E-C-S-S-S-E-S-G-W-T-T-Y-L-S-S-P-I-K-V-D-E-D-E-V-V-D-E-D-Y-Y-Y-E-G-Y-N-I-Y-N-Y-S-S-K-V-E-H-E-E-E-R-N-K-D-S-D-D-S-M-A-S-D-A-S-S-G-P-N-Y-Q-R-F-H-Q-K-N-K-A-L-D-L-K-N-G-K-N-E-G-N-S-K-S-K-N-D-D-D-H-H-N-H-Y-H-D-G-K-K-T-S-N-S-Y-R-K-K-D-K-K-K-R-E-N-K-S-T-Y-R-M-K"} +{"text": "### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-S-P-S-E-S-A-K-K-N-E-K-I-S-E-E-A-T-V-E-S-K-A-F-S-I-S-V-E-K-Q-T-P-D-L-D-G-L-I-V-E-E-L-C-M-G-N-P-N-G-K-K-A-E-P-G-K-R-V-S-V-H-Y-T-G-K-L-Q-G-N-G-K-I-F-D-S-T-V-G-K-S-R-Y-K-F-R-L-D-A-G-K-V-I-K-G-L-D-V-G-L-N-G-M-L-V-G-G-K-R-K-L-T-I-P-P-E-M-G-Y-G-A-E-G-A-G-S-I-P-P-D-S-W-L-V-F-D-V-E-L-L-N-V-K"} +{"text": "### FUNCTION This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport ### SEQUENCE -M-A-G-H-K-I-A-H-A-T-L-K-G-P-S-V-V-K-E-L-V-I-G-L-T-L-G-L-A-A-G-G-L-W-K-M-H-H-W-N-E-Q-R-K-T-R-V-F-Y-D-L-L-E-R-G-E-I-G-V-V-V-T-E-E"} +{"text": "### FUNCTION May be necessary for the splicing of pre-mRNA ### SEQUENCE -M-T-T-I-S-L-R-K-S-N-T-R-L-P-P-E-V-N-R-V-L-Y-V-R-N-L-P-F-N-I-T-S-E-E-M-Y-D-I-F-G-K-Y-G-A-I-R-Q-I-R-I-G-C-D-K-A-T-K-G-T-A-F-V-V-Y-E-D-I-Y-D-A-K-N-A-V-D-H-L-S-G-F-N-V-A-N-R-Y-L-I-V-L-Y-Y-Q-H-A-K-M-S-K-K-F-D-Q-K-K-S-E-D-E-I-T-K-L-Q-E-K-Y-G-V-S-T-K-D-K"} +{"text": "### FUNCTION This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport ### SEQUENCE -M-A-N-V-Q-K-I-G-K-A-V-Y-K-G-P-S-V-V-K-E-I-I-Y-G-I-T-L-G-F-A-V-G-G-L-W-K-M-H-H-W-N-N-Q-R-R-T-K-E-F-Y-D-L-L-E-K-G-E-I-S-V-V-V-E-D-E"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-A-M-Q-K-A-K-E-I-V-N-S-E-S-V-V-V-F-S-K-T-Y-C-P-Y-C-V-R-V-K-E-L-L-Q-Q-L-G-A-K-F-K-A-V-E-L-D-T-E-S-D-G-S-Q-I-Q-S-G-L-A-E-W-T-G-Q-R-T-V-P-N-V-F-I-G-G-N-H-I-G-G-C-D-A-T-S-N-L-H-K-D-G-K-L-V-P-L-L-T-E-A-G-A-I-A-G-K-T-A-T-T-S-A"} +{"text": "### FUNCTION A1b binds to basic 7S globulin and stimulates its phosphorylation activity ### SEQUENCE -A-A-D-C-N-G-A-C-S-P-F-E-M-P-P-C-R-S-T-D-C-R-C-I-P-I-A-L-F-G-G-F-C-I-N-P-T-G-L-S-S-V-A-K-M-I-D-E-H-P-N-L-C-Q-S-D-D-E-C-L-K-K-G-S-G-N-F-C-A-R-Y-P-N-H-Y-M-D-Y-G-W-C-F-D-S-D-S-E-A-L"} +{"text": "### FUNCTION A1b binds to basic 7S globulin and stimulates its phosphorylation activity ### SEQUENCE -A-A-D-C-N-G-A-C-S-P-F-Q-M-P-P-C-G-S-T-D-C-L-C-I-P-A-G-L-L-F-V-G-Y-C-T-Y-P-S-G-L-S-S-V-A-K-M-I-D-E-H-P-N-L-C-Q-S-D-D-E-C-M-K-K-G-S-G-N-F-C-A-R-Y-P-N-N-Y-M-D-Y-G-W-C-F-D-S-D-S-E-A-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-S-R-Y-R-G-P-R-T-K-I-I-R-R-L-G-A-L-P-G-L-T-S-K-I-L-E-L-E-S-G-Y-I-G-Q-S-T-P-N-K-K-V-S-Q-Y-R-I-R-L-E-E-K-Q-K-L-R-F-H-Y-G-L-T-E-R-Q-L-L-K-Y-V-R-I-A-R-K-A-K-G-S-T-G-Q-I-L-S-Q-T-L-E-M-R-L-D-N-I-I-F-R-L-G-M-S-P-T-I-P-G-A-R-Q-L-V-N-H-R-H-I-L-I-N-D-N-T-V-D-I-P-S-Y-N-C-E-P-K-D-V-I-T-V-N-N-R-K-E-S-V-I-I-K-N-M-D-S-S-R-K-P-K-V-P-N-H-L-T-F-D-S-I-R-F-R-G-S-V-N-Q-T-I-D-R-E-C-I-D-L-K-I-N-E-L-L-V-V-E-Y-Y-S-R-Q-V"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-E-H-L-M-C-D-V-G-D-G-Q-G-H-H-L-A-A-A-A-I-F-G-H-D-G-S-V-W-A-Q-S-A-N-F-P-Q-F-K-G-Q-E-F-A-N-I-M-K-D-F-D-E-P-G-H-L-A-P-T-G-L-F-L-A-G-A-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-A-G-G-I-T-I-K-K-T-G-Q-S-C-V-F-G-I-Y-E-E-P-V-T-P-G-Q-C-N-M-V-V-E-R-L-G-D-Y-L-I-E-Q-D-L"} +{"text": "### FUNCTION Actin-depolymerizing protein Severs actin filaments ### SEQUENCE -M-A-N-A-A-S-G-M-A-V-H-D-D-C-K-L-K-F-L-E-L-K-A-K-R-T-Y-R-F-I-I-Y-K-I-E-E-K-Q-K-E-V-V-V-E-K-L-G-E-P-T-E-S-Y-E-D-F-T-A-G-L-P-A-D-E-C-R-Y-A-V-Y-D-F-D-F-M-T-K-E-N-H-Q-K-S-R-I-F-F-I-A-W-S-P-D-T-A-R-V-R-S-K-M-I-Y-A-S-S-K-D-R-F-K-R-E-L-D-G-I-Q-V-E-L-Q-A-T-D-P-T-E-M-G-L-D-V-F-R-S-R-A-G-G-I-E-C"} +{"text": "### FUNCTION Actin-depolymerizing protein Severs actin filaments ### SEQUENCE -M-A-N-A-A-S-G-M-A-V-H-D-D-C-K-L-R-F-L-E-L-K-A-K-R-T-H-R-F-I-V-Y-K-I-E-E-K-Q-K-Q-V-V-V-E-K-I-G-E-P-T-E-S-Y-E-D-F-A-A-S-L-P-E-N-E-C-R-Y-A-V-Y-D-F-D-F-V-T-A-E-N-C-Q-K-S-R-I-F-F-I-A-W-C-P-D-T-A-R-V-R-S-K-M-I-Y-A-S-S-K-D-R-F-K-R-E-L-D-G-I-Q-V-E-L-Q-A-C-D-P-T-E-M-G-L-D-V-I-Q-S-R-A-N"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-V-D-Q-S-P-R-R-V-V-V-A-A-L-L-L-F-V-V-L-C-D-L-S-N-S-A-G-A-A-N-S-V-S-A-F-V-Q-N-A-I-L-S-N-K-I-V-I-F-S-K-S-Y-C-P-Y-C-L-R-S-K-R-I-F-S-Q-L-K-E-E-P-F-V-V-E-L-D-Q-R-E-D-G-D-Q-I-Q-Y-E-L-L-E-F-V-G-R-R-T-V-P-Q-V-F-V-N-G-K-H-I-G-G-S-D-D-L-G-A-A-L-E-S-G-Q-L-Q-K-L-L-A-A-S"} +{"text": "### FUNCTION Core component of nucleosome Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling ### SEQUENCE -M-A-R-T-K-Q-S-A-R-K-S-H-G-G-K-A-P-T-K-Q-L-A-T-K-A-A-R-K-S-A-P-T-T-G-G-V-K-K-P-H-R-F-R-P-G-T-V-A-L-R-E-I-R-K-Y-Q-K-S-T-E-L-L-N-R-K-L-P-F-Q-R-L-V-R-E-I-A-Q-D-F-K-T-D-L-R-F-Q-S-H-A-V-L-A-L-Q-E-A-A-E-A-Y-L-V-G-L-F-E-D-T-N-L-C-A-I-H-A-K-R-V-T-I-M-P-K-D-V-Q-L-A-R-R-I-R-A-E-R-A"} +{"text": "### FUNCTION Provide a mechanistic link between auxin and plasma membrane H ### SEQUENCE -M-A-I-I-N-R-S-K-L-T-Q-T-T-M-I-K-Q-I-L-K-R-C-S-S-L-G-K-K-Q-S-S-E-Y-N-D-T-H-E-H-D-G-D-S-L-P-L-D-V-P-K-G-H-F-V-V-Y-V-G-G-N-R-V-R-Y-V-L-P-I-S-F-L-T-R-P-E-F-Q-L-L-L-Q-Q-A-E-E-E-F-G-F-D-H-N-M-G-L-T-I-P-C-E-E-V-A-F-K-S-L-I-T-S-M-L-Q-P-T-Y-I"} +{"text": "### FUNCTION Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione ### SEQUENCE -M-A-S-Q-S-S-K-P-Q-S-I-Y-D-F-T-V-K-D-A-K-G-N-D-V-D-L-S-I-Y-K-G-K-V-L-I-I-V-N-V-A-S-Q-C-G-L-T-N-S-N-Y-T-D-M-T-E-I-Y-K-K-Y-K-D-Q-G-L-E-I-L-A-F-P-C-N-Q-F-G-G-Q-E-P-G-S-I-E-E-I-Q-N-M-V-C-T-R-F-K-A-E-Y-P-I-F-D-K-V-D-V-N-G-D-N-A-A-P-L-Y-K-F-L-K-S-S-K-G-G-F-F-G-D-S-I-K-W-N-F-S-K-F-L-V-D-K-E-G-N-V-V-D-R-Y-S-P-T-T-T-P-A-S-M-E-K-D-I-K-K-L-L-G-V-A"} +{"text": "### FUNCTION Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors ### SEQUENCE -M-E-A-T-R-S-D-D-P-S-L-N-P-I-R-N-R-N-P-N-P-N-P-N-P-N-P-L-S-T-I-I-S-S-A-Q-V-W-P-T-I-D-G-P-L-G-L-T-E-E-A-S-V-D-Y-A-R-R-F-Y-K-F-G-F-A-L-L-P-W-L-W-F-V-N-C-F-Y-F-W-P-V-L-R-H-S-R-A-F-P-Q-I-R-N-Y-V-V-R-S-A-I-G-F-S-V-F-T-A-L-L-S-A-W-A-L-T-F-S-I-G-G-E-Q-L-F-G-P-L-Y-D-K-L-V-M-Y-N-V-A-D-R-L-G-L-S-G-L-A"} +{"text": "### FUNCTION Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light ### SEQUENCE -M-T-S-T-N-T-R-N-K-G-K-C-I-V-E-G-P-P-P-T-L-S-R-Y-E-S-Q-K-S-R-D-W-N-T-F-C-Q-Y-L-M-T-K-M-P-P-V-H-V-W-E-C-E-S-N-H-I-L-D-F-L-Q-S-R-D-Q-F-G-K-T-K-V-H-I-Q-G-C-V-F-F-G-Q-K-E-P-P-G-E-C-N-C-P-L-K-Q-A-W-G-S-L-D-A-L-I-G-R-L-R-A-A-Y-E-E-N-G-G-L-T-E-K-N-P-F-A-R-G-G-I-R-I-F-L-R-E-V-R-G-S-Q-A-K-A-R-G-V-L-Y-K-K-K-K-R-L-V-V-V-G-T-G-T-S-T-T-W-T"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-E-D-Q-I-R-Q-L-K-D-I-F-D-R-F-D-M-D-A-D-G-S-L-T-I-L-E-L-A-A-L-L-R-S-L-G-L-K-P-S-G-D-Q-I-H-V-L-L-A-S-M-D-S-N-G-N-G-F-V-E-F-D-E-L-V-G-T-I-L-P-D-L-N-E-E-V-L-I-N-S-E-Q-L-L-E-I-F-K-S-F-D-R-D-G-N-G-F-I-S-A-A-E-L-A-G-A-M-A-K-M-G-Q-P-L-T-Y-K-E-L-T-E-M-I-K-E-A-D-T-N-G-D-G-V-I-S-F-G-E-F-A-S-I-M-A-K-S-A-V-D-Y-F-G-L-K-I-N-S"} +{"text": "### FUNCTION Probable transcriptional regulator ### SEQUENCE -M-V-Q-C-T-D-C-K-K-W-R-L-I-P-S-M-Q-H-Y-N-I-I-K-E-T-Q-L-Q-T-P-F-V-C-G-T-T-S-G-W-T-P-N-M-S-C-N-V-P-Q-D-G-T-T-C-D-T-W-P-S-I-P-P-I-P-T-G-W-S-R-S-V-H-I-R-S-E-S-T-K-F-A-D-V-Y-Y-F-P-P-S-G-E-R-L-R-S-S-A-E-V-Q-S-F-L-D-N-H-P-E-Y-V-R-E-G-V-N-R-S-Q-F-S-F-Q-I-P-K-P-L-D-D-N-Y-V-K-K-R-T-R-P-V-K-R-R-K-S-S-K-D-N-N-C-E-K-G-K-K"} +{"text": "### FUNCTION Inhibits the host uracil-DNA glycosylase ### SEQUENCE -M-N-K-E-K-N-S-Y-R-D-A-I-K-D-V-E-L-T-M-M-A-I-D-S-H-F-R-T-H-K-G-F-T-D-S-Y-L-L-V-M-I-L-E-N-E-V-G-E-T-R-L-E-V-S-E-G-L-T-F-D-E-V-G-Y-I-V-G-S-V-S-D-N-I-L-H-M-H-T-Y-N-Y-C-E-K-N-R-E-D-I-Y-K-W-L-K-A-S-R-I-E-K-F-K-S-D-Y-A-K-M-L-M-N-M-H-F-G-K-E-N-N-V-G-S-N-I-N-L-K-E-E-F"} +{"text": "### FUNCTION Mediates ssDNA packaging into virion, it locates to the internal surface of the capsid, thereby displacing the internal scaffolding protein VP3 during virion formation Additionally, protein VP8 plays a role in viral attachment to the host cell ### SEQUENCE -M-K-R-K-P-M-S-R-K-A-S-Q-K-T-F-K-K-N-T-G-V-Q-R-M-N-H-L-N-P-R-A-M-R-G-G-I-R-L"} +{"text": "### FUNCTION Participates in the assembly of the viral procapsid in the cytoplasm Internal scaffolding protein VP3 is released from the procapsid upon genome packaging, possibly through affinity displacement by the protein VP8, or by proteolysis ### SEQUENCE -M-K-K-I-E-L-R-P-N-G-T-K-L-V-H-T-V-N-E-L-P-P-E-T-D-Q-S-F-G-K-E-C-D-I-N-F-I-V-K-K-F-I-K-T-G-Q-I-T-H-L-A-R-R-Q-G-F-Y-G-D-Q-S-S-I-P-D-F-Q-T-A-M-D-T-V-T-K-A-Q-Q-A-F-D-E-L-P-A-H-M-R-K-R-F-A-N-S-P-H-E-L-M-Q-F-L-Q-D-P-K-N-R-D-E-A-I-S-L-G-L-M-E-M-V-E-T-P-Q-Q-A-P-Q-S-T-T-N-Q-T-T-T-K-P-A-P-A-S-G-E-P-T-P-V-P-T-P"} +{"text": "### FUNCTION Probably triggers with protein G the injection of the phage DNA into the host upon conformational changes induced by virus-host receptor interaction ### SEQUENCE -M-A-L-P-A-L-V-A-A-A-A-P-A-V-I-G-G-I-A-S-Y-F-G-Q-Q-E-T-N-A-A-N-A-K-L-A-V-W-Q-T-R-E-N-Q-A-E-A-A-R-N-R-K-W-Q-E-Q-M-S-N-S-A-H-Q-R-E-A-N-D-L-Q-T-A-G-L-N-R-L-L-T-A-T-G-G-A-S-T-P-S-G-G-Q-G-Q-A-A-G-A-T-M-E-N-S-L-K-A-G-I-T-T-A-F-E-A-K-Q-L-G-M-Q-I-E-R-Q-E-K-E-L-Q-N-L-A-A-Q-T-R-K-L-N-I-D-A-K-V-A-E-K-R-I-P-E-S-D-L-K-T-K-F-T-T-N-F-S-P-V-I-D-R-V-I-N-L-E-D-S-N-G-P-R-L-S-N-L-R-E-E-K-K-P-N-Q-M-P-L-K-N-G-K-L-N-T"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-M-K"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-R-I-S-T-K-K-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-I-T-L-H-M-V-V-L-P-F-L-I-T-L-F-L-L-L-I-I-K-F-L-P-M-N-V-P-D-K-E-K-L-S-P-Y-E-C-G-F-D-P-S-G-S-A-R-L-P-F-S-M-K-F-F-L-V-A-I-L-F-I-L-F-D-L-E-I-I-L-L-F-P-L-A-W-A-L-N-S-Q-S-H-S-N-A-I-I-L-A-S-V-F-V-I-I-L-T-L-G-L-I-Y-E-W-L-K-G-G-L-E-W-T-E"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-N-W-R-S-K-R-I-W-I-E-L-I-T-G-S-R-K-I-S-N-F-C-W-A-F-I-L-F-L-G-S-L-G-F-L-L-V-G-I-S-S-Y-L-G-R-N-L-I-S-L-F-P-P-Q-Q-I-L-F-F-P-Q-G-I-V-M-S-F-Y-G-I-A-G-L-F-I-S-S-Y-L-W-C-T-I-S-W-N-V-G-S-G-Y-D-R-F-D-R-K-E-G-I-V-C-I-F-R-W-G-F-P-G-K-N-R-R-I-F-L-R-F-L-I-K-D-I-Q-S-I-R-I-E-L-K-E-G-I-Y-T-R-R-V-L-Y-L-E-I-R-G-Q-G-A-I-P-L-T-R-T-D-D-N-L-T-P-R-E-I-E-Q-K-A-A-E-L-A-Y-F-L-R-I-P-I-E-V-F"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-T-T-I-N-F-P-S-L-F-V-P-L-V-G-L-I-F-P-A-I-A-M-A-S-L-F-L-Y-V-Q-K-N-K-I-V"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-S-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-N-K-K-I-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-A-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-N-L-V-T-I-S-I-S-C-L-L-V-S-L-T-G-Y-A-I-Y-T-S-F-G-R-P-S-E-Q-L-K-D-P-F-E-D-H-E-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-L-F-F-A-I-F-F-R-E-P-P-R-V-T-P-K-G-G-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-R-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-E-Q-L-R-D-P-F-E-E-H-E-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-D-P-P-K-V-P-N-E-G-R-K"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-R-M-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-T-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-I-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-L-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-X-I-S-I-S-G-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-A-K"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-X-I-L-T-K-K-T-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-T-N-P-N-E-Q-S-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-G-T-A-E-E-K-T-A-K-S-D-P-I-Y-R-N-R-L-V-T-M-L-V-N-R-I-L-K-H-G-K-K-S-L-A-Y-Q-I-I-Y-R-A-V-K-K-I-Q-Q-K-T-E-T-N-P-L-S-V-L-R-Q-A-I-R-G-V-T-P-D-I-A-V-K-A-R-R-V-G-G-S-T-H-Q-V-P-I-E-I-G-S-T-Q-G-K-A-L-A-I-R-W-L-L-G-A-S-R-K-R-P-G-R-N-M-A-F-K-L-S-S-E-L-V-D-A-A-K-G-S-G-D-A-I-R-K-K-E-E-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-G-T-T-E-E-K-T-A-K-S-D-P-I-Y-R-N-R-L-V-N-M-L-V-N-R-I-L-K-H-G-K-K-S-L-A-Y-Q-I-I-Y-R-A-V-K-K-I-Q-Q-K-T-E-T-N-P-L-S-V-L-R-Q-A-I-R-G-V-T-P-D-I-A-V-K-A-R-R-V-G-G-S-T-H-Q-V-P-I-E-I-G-S-T-Q-G-K-A-L-A-I-R-W-L-L-W-A-S-R-K-R-P-G-R-N-M-A-F-K-L-S-S-E-L-V-D-A-A-K-G-S-G-D-A-I-R-K-K-E-E-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-G-T-A-E-E-K-T-A-K-S-D-P-I-Y-R-N-R-L-V-N-M-L-V-N-R-I-L-K-H-G-K-K-S-L-A-Y-Q-I-L-Y-R-A-V-K-K-I-Q-Q-K-T-E-T-N-P-L-S-V-L-R-Q-A-I-R-G-V-T-P-D-I-V-V-K-A-R-R-V-G-G-S-T-H-Q-V-P-I-E-I-G-S-T-Q-G-K-A-L-A-I-R-W-L-L-V-A-S-R-K-R-P-G-R-N-M-A-F-K-L-S-S-E-L-V-D-A-A-K-G-G-G-D-A-I-R-K-K-E-E-T-H-K-M-A-E-A-N-R-A-F-A-H-F-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-S-T-A-E-K-E-T-A-K-S-D-P-I-Y-R-N-R-F-I-N-M-L-V-N-R-I-L-K-H-G-K-K-S-L-A-Y-R-I-L-Y-R-A-M-K-K-I-Q-Q-K-T-G-K-N-P-L-S-V-S-R-Q-A-I-R-G-V-T-P-D-V-T-V-K-A-R-R-V-G-G-S-T-Y-Q-V-P-I-E-I-R-S-T-Q-G-K-A-L-A-I-R-W-L-L-G-A-S-R-K-R-P-G-R-N-M-A-F-K-L-S-Y-E-L-M-D-A-A-R-E-N-G-N-A-I-R-K-K-E-E-T-H-R-M-A-E-A-X-R-A-F-A-H-F-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-G-T-A-E-E-K-T-A-K-S-D-P-I-Y-R-N-R-L-V-N-M-L-V-N-R-I-L-K-H-G-K-K-S-L-A-Y-Q-I-I-Y-R-T-V-K-K-I-Q-Q-K-T-E-T-N-P-L-S-V-L-R-Q-A-I-R-G-V-T-P-D-I-A-V-K-A-R-R-V-G-G-S-T-H-Q-V-P-I-E-I-G-S-T-Q-G-K-A-L-A-I-R-W-L-L-G-A-S-R-K-R-P-G-R-N-M-A-F-K-L-S-S-E-L-V-D-A-A-K-G-S-G-D-A-I-R-K-K-E-E-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-G-T-A-E-E-K-T-A-K-S-D-P-I-Y-R-N-R-L-V-N-M-L-V-N-R-I-L-K-H-G-K-K-S-L-A-Y-Q-I-V-Y-Q-A-V-K-K-I-Q-Q-K-T-E-T-N-P-L-S-V-L-R-Q-A-I-C-R-V-T-P-D-I-A-V-K-A-R-R-V-G-G-S-T-H-Q-V-P-I-E-I-G-S-T-Q-G-K-A-L-A-I-R-W-L-L-G-A-S-R-K-R-P-G-R-N-M-A-F-K-L-S-S-E-L-V-D-A-A-K-G-S-G-D-A-I-R-K-K-E-E-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-G-T-A-E-E-K-T-A-K-S-D-P-I-Y-R-N-R-L-V-N-M-L-V-N-R-I-L-K-H-G-K-K-S-L-A-Y-Q-I-I-Y-R-A-V-K-K-I-Q-Q-K-T-E-T-N-P-L-S-V-L-R-Q-A-I-R-G-V-T-P-N-I-A-V-K-A-R-R-V-G-G-S-T-H-Q-V-P-I-E-I-G-S-T-Q-G-K-A-L-A-I-R-W-L-L-G-A-S-R-K-R-P-G-R-N-M-A-F-K-L-S-S-E-L-V-D-A-A-K-G-S-G-D-A-I-R-K-K-E-E-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-G-T-A-E-E-K-T-A-K-S-D-P-I-Y-R-N-R-L-V-N-M-L-V-N-R-I-L-K-H-G-K-K-S-L-A-Y-Q-I-I-Y-R-A-V-K-K-I-Q-Q-K-T-E-T-N-P-L-S-V-L-R-Q-A-I-R-G-V-T-P-D-I-A-V-K-A-R-R-V-G-G-S-T-H-Q-V-P-I-E-I-G-S-T-Q-G-K-A-L-A-I-R-W-L-L-G-A-S-R-K-R-P-G-R-N-M-A-L-K-L-S-S-E-L-V-D-A-A-K-G-S-G-D-A-I-R-K-K-E-E-T-H-K-M-A-E-A-N-R-A-F-A-H-F-R"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-K-K-S-M-I-Q-R-E-L-K-R-Q-K-L-V-M-K-Y-A-T-K-R-A-A-L-K-E-Q-I-K-Q-T-T-F-L-K-E-K-L-S-L-H-R-K-L-Q-Q-L-P-R-N-S-S-A-V-R-L-H-N-R-C-M-I-T-G-R-P-K-G-Y-F-R-D-F-G-L-S-R-H-V-L-R-E-M-A-H-Q-G-L-L-P-G-V-C-K-S-S-W"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-R-C-R-S-Q-S-R-S-R-C-C-R-P-R-R-R-C-R-R-R-R-R-S-C-R-A-R-R-R-A-T-R-C-C-R-R-R-Y-R-L-R-C-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-C-R-R-R-R-R-C-R-R-R-R-R-R-R-C-R-A-R-R-R-A-M-R-C-C-R-R-R-Y-R-L-R-C-R-R-Y"} +{"text": "### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-M-A-R-I-F-I-L-A-L-L-G-Q-L-C-F-L-P-Y-L-D-A-I-T-S-S-P-K-V-Q-V-Y-S-R-H-P-V-D-S-N-K-E-N-F-V-N-C-F-V-S-G-F-H-P-P-Q-I-T-I-E-L-S-K-D-G-E-K-I-P-K-V-E-E-S-D-L-S-F-S-N-D-W-T-F-N-R-L-V-S-A-P-F-D-P-N-S-R-S-E-Y-T-C-K-V-T-H-L-T-L-Q-E-P-K-V-V-K-W-D-P-E-N-N"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-R-S-R-S-R-C-Y-R-R-R-R-R-C-R-T-R-R-R-R-C-C-R-R-R-R-A-R-R-C-C-R-R-R-Y-K-L-R-C-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-C-R-P-R-R-R-C-R-R-R-R-R-R-S-C-R-A-R-R-R-A-T-R-C-C-R-R-R-Y-R-L-R-S-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-K-S-R-C-C-G-S-Q-S-R-S-R-C-C-R-P-R-Q-R-C-R-R-R-R-R-R-S-C-R-A-R-R-R-A-M-R-C-C-R-R-R-Y-R-L-R-C-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-C-R-P-R-R-R-C-R-R-R-R-R-R-S-C-R-A-R-R-R-A-T-R-C-C-R-R-R-Y-R-L-R-C-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-R-R-S-Q-S-R-S-R-C-C-R-Q-R-R-R-C-R-R-R-R-R-Q-R-F-R-A-R-K-R-A-M-R-C-C-H-R-R-Y-R-L-R-C-R-R-Y"} +{"text": "### FUNCTION Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase 9 ### SEQUENCE -I-L-K-K-D-N-Y-S-Y-I-S-F-Y-N-A-L-I-H-E-G-Y-K-D-L-A-A-L-L-H-S-G-I-P-V-I-S-S-S-N-G-G-K-D-S-V-G-G-I-T-S"} +{"text": "### FUNCTION Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase , that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c ### SEQUENCE -M-T-T-L-R-S-A-V-A-K-V-S-E-T-W-K-M-K-I-A-Q-R-S-F-F-E-K-T-I-K-D-F-N-F-N-T-G-Y-Y-N-Q-I-G-L-R-W-H-D-I-M-P-R-N-A-V-V-E-E-A-F-R-R-L-P-R-E-E-R-E-D-M-D-F-R-L-A-R-A-T-L-L-S-A-N-K-T-I-L-S-K-E-E-W-T-K-Q-E-E-D-V-P-Y-L-D-P-Y-I-K-L-I-E-R-E-L-R-N-K-A-D-W-D-N-F-I-S-P-R-T-Y-P"} +{"text": "### FUNCTION May play a role in chromosome segregation through establishment of sister chromatid cohesion ### SEQUENCE -M-I-M-N-Y-N-V-I-D-K-I-D-V-F-D-I-I-R-H-I-K-D-P-E-F-P-K-T-L-E-E-L-K-V-V-N-E-D-W-I-T-V-I-D-N-N-D-I-N-D-S-D-D-I-N-N-N-N-N-E-N-Y-K-G-Y-C-F-I-K-I-L-F-Q-P-T-V-P-H-C-H-L-A-P-T-I-A-L-C-I-R-E-K-I-K-E-Y-L-P-K-R-S-K-I-E-I-Y-I-K-K-G-T-H-Q-T-E-D-E-I-N-K-Q-I-N-D-K-E-R-I-I-A-A-L-E-N-P-E-I-F-Q-L-V-K-K-C-I-K-E-D-D-Y"} +{"text": "### FUNCTION Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 ### SEQUENCE -M-N-R-A-K-V-L-S-S-Y-L-G-L-L-R-T-E-K-K-V-F-Q-N-D-K-R-A-L-E-H-V-I-N-L-T-R-V-Q-F-R-D-N-K-N-E-T-D-N-T-K-I-N-E-M-I-D-H-A-N-A-V-S-H-F-L-V-K-D-L-I-Q-G-V-R-K-D-E-K-T-I-Q-L-K-F-D-E-N-T-K-S-Y-Q-Q-Y-E-F-V-N-D-Q-P-P-Q-R-K-K-R-G-K-I-Q-I-D-D-E-Q-P-T-T-C-C-G-G-G-C-G-K-P-M-P-S-N-N-S-E-K-S-T-C-S"} +{"text": "### FUNCTION Plays an important role in the elongation step of protein synthesis ### SEQUENCE -M-K-Y-I-A-A-Y-A-L-L-V-L-G-G-N-S-S-P-S-A-D-D-V-K-K-V-L-K-S-V-G-V-D-S-E-Q-D-K-L-D-A-L-L-K-N-L-E-G-K-Q-L-H-E-L-I-E-A-G-S-S-K-V-S-S-L-S-A-G-A-G-P-S-G-G-A-A-A-A-G-A-D-A-G-A-A-E-A-E-K-E-E-E-P-Q-E-E-E-A-D-V-N-M-G-D-I-F-G-G-D-D-E-D-Y"} +{"text": "### FUNCTION Antibacterial peptide ### SEQUENCE -M-K-S-Q-T-F-F-L-L-F-L-V-V-L-L-L-A-I-S-Q-S-E-A-F-I-G-A-V-A-G-L-L-S-K-I-F-G-K-R-S-M-R-D-M-D-T-M-K-Y-L-Y-D-P-S-L-S-A-A-D-L-K-T-L-Q-K-L-M-E-N-Y"} +{"text": "### FUNCTION Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca complex are a number of protein kinases and phosphatases ### SEQUENCE -M-A-D-Q-L-T-E-E-Q-I-A-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-T-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-Q-D-M-I-N-E-V-D-A-D-G-N-G-T-I-D-F-P-E-F-L-T-M-M-A-R-K-M-K-D-T-D-S-E-E-E-I-R-E-A-F-R-V-F-D-K-D-G-N-G-F-I-S-A-A-E-L-R-H-V-M-T-N-L-G-E-K-L-T-D-E-E-V-D-E-M-I-R-E-A-D-I-D-G-D-G-Q-V-N-Y-E-E-F-V-T-M-M-M-S-K"} +{"text": "### FUNCTION Alpha toxins bind voltage-independently at site-3 of sodium channels and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission ### SEQUENCE -M-N-Y-L-V-F-F-S-L-A-L-L-L-M-T-G-V-E-S-V-R-D-G-Y-I-A-D-D-K-N-C-A-Y-F-C-G-R-N-A-Y-C-D-D-E-C-K-K-K-G-A-E-S-G-Y-C-Q-W-A-G-V-Y-G-N-A-C-W-C-Y-K-L-P-D-K-V-P-I-R-V-P-G-K-C-N-G-G"} +{"text": "### FUNCTION Myohemerythrin is an oxygen-binding protein found in the retractor muscles of certain worms The oxygen-binding site contains two iron atoms ### SEQUENCE -M-V-F-E-I-P-E-P-Y-Q-W-D-E-T-F-E-V-F-Y-E-K-L-D-E-E-H-K-G-L-F-K-G-I-K-D-L-S-D-S-P-A-C-S-E-T-L-E-K-L-V-K-L-I-E-D-H-F-T-D-E-E-E-M-M-K-S-K-S-Y-E-D-L-D-S-H-K-K-I-H-S-D-F-V-E-T-L-K-G-V-K-A-P-V-S-E-E-N-I-K-M-A-K-E-W-L-V-N-H-I-K-G-T-D-F-K-Y-K-G-K-L"} +{"text": "### FUNCTION Probable regulator of exocrine pancreas development ### SEQUENCE -M-A-A-I-P-S-S-G-S-L-V-A-T-H-D-Y-Y-R-R-R-L-G-S-T-S-S-N-S-S-C-S-S-T-E-C-P-G-E-A-I-P-H-P-P-G-L-P-K-A-D-P-G-H-W-W-A-S-F-F-F-G-K-S-T-L-P-F-M-A-T-V-L-E-S-A-E-H-S-E-P-P-Q-A-S-S-S-M-T-A-C-G-L-A-R-D-A-P-R-K-Q-P-G-G-Q-S-S-T-A-S-A-G-P-P-S"} +{"text": "### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane ### SEQUENCE -M-I-N-Q-G-L-F-I-R-V-N-N-F-Q-L-L-K-A-S-L-A-Y-K-K-A-S-N-I-L-T-F-P-P-I-R-T-S-T-K-H-G-G-G-S-S-K-N-T-G-D-S-A-G-R-R-L-G-I-K-R-S-E-N-Q-F-V-R-A-G-E-I-L-I-R-Q-R-G-T-K-F-H-P-G-D-N-T-G-L-G-K-D-H-T-I-Y-S-L-V-S-G-Y-V-K-F-F-Q-M-D-V-S-L-R-K-R-R-K-Y-V-G-V-V-F-D-K-E-T-T-L-P-R-P-K-D-E-P-T-I-R-R-V-N-K-Y-I-T-S-A-N-S-A-Q-V-S"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-V-R-Y-A-A-T-E-I-A-P-A-K-S-A-R-S-R-G-S-Y-L-R-V-S-F-K-N-T-R-E-T-A-Q-A-I-N-G-W-K-L-Q-R-A-Q-K-F-L-E-N-V-L-E-K-K-E-A-V-P-M-R-R-Y-A-G-G-T-G-R-A-A-Q-G-K-Q-F-G-V-S-R-A-R-W-P-A-K-S-A-E-F-L-L-G-L-L-K-N-A-E-A-N-A-D-A-K-G-L-D-T-G-N-L-V-V-K-H-I-Q-V-N-Q-A-P-K-Q-R-R-R-T-Y-R-A-H-G-R-I-N-P-Y-M-S-N-P-C-H-I-E-L-I-L-T-E-A-D-E-V-V-Q-K-S-E-A-V-V-R-E-E-A-H-L-S-S-R-Q-R-G-A-R-V-R-R-A-I-T-A-A"} +{"text": "### FUNCTION Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit ### SEQUENCE -M-S-S-A-I-P-T-S-S-V-N-P-V-K-G-M-R-K-N-G-K-N-W-H-D-S-K-K-P-F-R-P-T-S-G-L-T-S-Y-E-K-R-L-E-A-R-K-R-Q-E-A-V-K-E-H-E-R-E-L-R-E-E-K-E-A-E-R-K-A-Q-I-Q-K-I-K-D-R-R-A-A-K-E-E-K-E-R-Y-E-K-M-A-E-K-M-H-R-K-R-V-E-R-L-K-R-R-E-K-R-N-K-L-L-H-S"} +{"text": "### FUNCTION Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner It has the ability to bind G- and F-actin in a 11 ratio of cofilin to actin Binding to F-actin is regulated by tropomyosin It is the major component of intranuclear and cytoplasmic actin rods Required for accumulation of actin at the cell division site via depolymerizing actin at the cell ends In association with myosin II has a role in the assembly of the contractile ring via severing actin filaments Involved in the maintenance of the contractile ring once formed In association with profilin and capping protein, has a role in the mitotic reorganization of the actin cytoskeleton ### SEQUENCE -M-S-R-S-G-V-S-V-A-D-E-S-L-Q-A-F-N-D-L-K-L-G-K-K-Y-K-F-V-L-Y-G-I-S-E-D-K-T-T-I-V-V-K-E-T-S-T-S-Q-S-Y-D-E-F-L-G-K-L-P-E-N-D-C-L-Y-A-I-Y-D-F-E-Y-E-I-G-G-N-E-G-K-R-S-K-I-V-F-F-T-W-S-P-D-T-A-P-V-R-S-K-M-V-Y-A-S-S-K-D-A-L-R-R-A-L-T-G-V-S-S-D-I-Q-G-T-D-F-S-E-V-S-F-E-T-V-L-E-R-V-S-K-S-A-G-S-H"} +{"text": "### FUNCTION Necessary for protein translocation in the endoplasmic reticulum ### SEQUENCE -M-S-T-S-A-Q-V-P-G-G-P-A-A-Q-M-K-R-R-N-N-A-Q-R-Q-E-A-K-A-S-Q-R-P-T-S-T-R-S-V-G-A-G-G-S-S-S-T-M-L-K-L-Y-T-D-E-S-Q-G-L-K-V-D-P-V-V-V-M-V-L-S-L-G-F-I-F-S-V-V-A-L-H-I-L-A-K-V-S-T-K-L-L-G"} +{"text": "### FUNCTION Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane ### SEQUENCE -M-S-T-S-Q-S-S-E-Q-T-L-N-Y-Q-W-D-V-C-L-S-N-M-V-V-Q-S-G-I-G-L-G-A-G-I-V-S-S-V-L-F-F-R-R-A-A-W-P-V-W-G-G-L-G-F-G-L-G-K-S-Y-A-D-S-N-A-R-L-R-T-F-H-A-I-P-K-Q-L-P-A-S-S-T-Q-K-K-D"} +{"text": "### FUNCTION Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases ### SEQUENCE -M-T-A-K-I-F-S-L-D-E-V-S-K-H-K-T-K-S-D-L-W-V-V-I-H-N-K-V-Y-D-I-T-R-F-V-V-E-H-P-G-G-E-E-V-L-V-D-E-G-G-K-D-A-T-E-A-F-E-D-I-G-H-S-D-E-A-R-E-M-L-E-E-Y-L-I-G-S-L-D-E-A-S-R-T-K-E-Y-N-V-N-V-I-R-A-G-E-L-P-E-E-K-K-G-S-S-L-R-I-I-L-P-A-L-A-I-I-G-A-L-V-Y-K-Y-V-I-V-P-K-A-H-Q"} +{"text": "### FUNCTION Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca ### SEQUENCE -M-A-D-Q-L-T-E-E-Q-I-A-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-T-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-L-V-M-I-N-E-V-D-A-D-G-N-G-T-I-D-F-P-E-F-L-T-M-M-A-R-K-M-K-D-S-D-S-E-E-E-I-K-E-A-F-K-V-F-D-K-D-G-N-G-Y-I-S-A-A-E-L-R-H-V-M-T-N-L-G-E-K-L-S-E-D-E-V-E-E-M-I-R-E-A-D-V-D-G-D-G-Q-I-N-Y-E-E-F-V-K-M-M-M-S-K"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-S-S-L-A-D-T-I-H-I-E-N-V-V-A-S-S-D-L-G-Q-E-L-A-L-D-Q-L-A-T-D-L-D-G-A-E-Y-N-P-E-D-F-P-G-V-V-Y-R-L-Q-E-P-K-S-A-T-L-I-F-R-S-G-K-V-V-C-T-G-A-K-S-V-D-A-V-H-D-A-L-E-I-V-F-D-D-L-R-E-L-G-I-D-V-D-S-T-P-P-V-K-V-Q-N-I-V-S-S-A-S-L-E-Q-S-L-N-L-N-A-I-A-I-G-L-G-L-E-Q-I-E-Y-E-P-E-Q-F-P-G-L-V-Y-R-L-D-D-P-D-V-V-V-L-L-F-G-S-G-K-L-V-I-T-G-A-A-E-S-A-D-A-Q-H-A-L-A-H-V-N-D-R-L-T-E-L-G-L-L-E"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-S-S-D-Q-H-L-Q-V-S-K-I-Q-A-G-T-V-I-D-H-I-P-A-G-Q-A-L-Q-V-L-Q-I-L-G-T-N-G-A-S-D-D-Q-I-T-V-G-M-N-V-T-S-E-R-H-H-R-K-D-I-V-K-I-E-G-R-E-L-S-Q-D-E-V-D-V-L-S-L-I-A-P-D-A-T-I-N-I-V-R-D-Y-E-V-D-E-K-R-R-V-D-R-P-D-V-V-A-G-V-L-S-C-P-N-P-N-C-I-T-A-N-D-E-P-V-R-S-G-F-D-V-L-D-D-G-M-R-C-Q-Y-C-E-Q-I-V-S-E-D-I-P-S-L-I-D-P-E"} +{"text": "### FUNCTION May play a structural or regulatory role in gas vesicle synthesis ### SEQUENCE -M-P-T-D-D-P-S-D-R-P-S-G-L-L-D-Q-L-S-R-L-I-E-T-L-A-E-L-D-D-D-N-G-E-Q-H-G-H-S-T-I-D-R-G-R-T-R-I-D-Y-D-Y-A-V-S-I-G-L-G-S-D-A-R-S-P-S-T-P-A-G-N-A-D-D-A-G-D-A-E-T-A-H-I-E-T-R-A-S-D-D-S-D-D-L-V-V-V-A-D-L-P-G-V-T-D-E-T-A-V-D-A-A-V-E-D-T-G-A-L-T-I-S-V-G-D-D-V-V-E-R-L-T-L-D-D-P-G-M-T-I-T-S-L-T-V-T-N-Q-I-L-E-L-R-V-T-P-S-E-P-S-A-T-D-T"} +{"text": "### FUNCTION May play a structural or regulatory role in gas vesicle synthesis ### SEQUENCE -M-T-P-T-N-R-H-T-H-G-Q-N-A-Q-H-A-R-R-N-A-Q-Q-S-R-D-A-A-R-R-K-L-I-A-Q-H-A-A-L-A-E-Q-R-A-R-N-R-R-R-S-D-T-E-Q-P-T-S-D-T-T-N-P-A-A-H-S-T-L-P-A-Q-R-T-N-A-Q-N-A-A-R-N-A-H-S-T-V-P-E-Q-P-T-H-A-T-T-A-A-R-A-R-L-Y-G-L-R-L-H-N-T-A-T-T-D-K"} +{"text": "### FUNCTION Involved in regulation of DNA replication ### SEQUENCE -M-V-K-G-T-P-L-S-G-K-S-L-L-F-A-L-T-R-L-D-R-N-N-P-E-K-E-W-F-R-T-S-E-I-H-E-V-Y-Q-T-V-A-R-D-V-E-V-E-P-K-G-Y-N-R-A-L-E-L-L-N-K-H-V-T-T-G-V-L-E-S-K-K-K-E-R-G-D-Q-G-K-F-R-S-Y-S-L-Q-G-D-V-E-S-T-R-T-G-L-I-N-S-T-P-E-L-Q-T-L-M-G-W"} +{"text": "### FUNCTION May play a structural or regulatory role in gas vesicle synthesis ### SEQUENCE -M-S-D-K-Q-Q-Q-K-H-K-Q-K-A-R-Q-A-R-V-K-A-Q-I-N-R-D-K-A-R-R-N-L-L-R-Q-R-E-K-L-A-R-R-R-T-R-N-R-K-Q-S-E-P-R-R-D-D-S-D-G-D-D-T-D-G-E-T-V-K-N-P-A-A-H-S-T-M-P-P-Q-K-S-N-A-E-N-A-V-R-N-S-H-S-T-V-P-K-T-P-K-Y-S-D-V-T-A-R-E-R-L-Y-G-Q-R-L-H-Q-K-T-A-G-G-N-S-E-A-S-A-P-S-D-E-S-A-S-G-S-P-T-E-D-E-V-N-D-E"} +{"text": "### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-I-P-G-R-M-N-S-R-E-M-R-R-L-M-A-Q-M-G-I-K-S-T-E-M-D-D-V-T-K-V-I-F-K-G-K-T-K-D-Y-V-I-D-N-A-Q-V-T-M-I-E-A-Q-G-V-K-T-F-Q-V-V-G-T-M-R-E-V-P-K-E-P-E-E-K-K-E-E-S-F-P-E-D-D-I-K-L-V-M-E-Q-A-S-V-S-R-E-K-A-I-E-A-L-K-A-S-G-G-E-P-A-Q-A-I-M-N-L-M-Q-K"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-I-M-T-E-V-P-E-G-L-N-Y-T-K-T-H-E-W-Y-R-K-D-G-N-T-A-T-I-G-I-T-D-Y-A-Q-S-Q-M-T-D-I-V-Y-V-D-L-P-K-V-G-D-K-K-K-A-G-D-V-L-L-T-I-E-S-V-K-S-A-E-D-V-Y-S-P-I-T-G-T-V-T-A-V-N-E-E-V-A-K-H-P-E-S-I-N-K-D-P-Y-G-S-W-L-V-K-M-A-I-E-S-E-G-E-H-L-S-A-S-E-Y-R-K-L-I-Q"} +{"text": "### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-K-G-D-I-I-I-S-P-L-S-T-E-K-T-A-L-M-A-E-K-E-N-K-L-T-L-M-V-R-R-D-A-N-R-E-M-I-K-K-E-V-E-E-R-F-G-V-K-V-E-G-I-N-V-M-I-T-K-K-G-K-K-A-I-V-K-L-A-K-E-Y-S-A-E-E-I-A-E-R-I-G-V-F"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-V-V-N-K-Q-G-S-V-K-S-I-K-R-K-A-R-K-S-K-K-V-V-S-G-R-A-K-E-F-T-Y-K-G-Y-S-L-E-D-L-Q-K-M-S-M-E-E-L-I-K-I-L-P-A-R-A-R-R-T-L-L-R-E-P-N-Y-E-Q-K-K-L-M-E-K-L-E-S-D-E-E-D-V-K-T-H-V-R-D-V-I-I-L-P-N-Y-V-G-K-I-V-E-V-Y-N-G-N-S-Y-F-K-F-E-I-K-P-E-M-I-G-H-Y-L-G-E-F-V-M-T-R-K-E-V-K-H-S-G-P-G-V-G-A-T-R-S-S-K-F-M-P-L-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-I-I-M-K-G-Y-S-M-E-I-E-G-N-H-A-K-A-R-I-R-E-A-D-I-S-L-K-D-S-V-N-I-A-H-H-L-R-G-M-P-L-S-R-A-K-E-I-I-D-A-V-I-N-K-T-Y-A-I-P-Y-F-R-Y-L-D-S-V-S-H-R-P-G-V-G-P-G-R-Y-P-V-K-A-A-K-A-F-K-Q-L-L-E-N-V-E-N-N-A-E-F-K-G-L-N-T-D-N-L-V-I-K-H-I-A-A-N-K-G-R-M-I-K-K-Y-T-P-K-A-Y-G-R-A-G-A-N-F-K-D-L-I-N-L-E-I-I-V-T-E-G-S-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-Y-T-R-N-I-G-L-D-V-K-L-P-E-S-E-C-N-D-P-H-C-P-Y-H-G-K-L-S-V-R-G-Q-V-L-T-G-K-V-V-S-A-N-M-T-K-S-A-V-V-A-R-E-Y-Q-Q-Y-I-P-K-Y-E-R-K-A-T-K-I-K-K-Y-H-V-H-V-P-D-C-I-K-I-K-P-G-D-T-V-R-F-A-E-C-R-K-L-A-K-T-I-S-F-V-I-V-E-K-V-N-Q"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-K-G-I-A-G-R-Q-T-R-G-L-P-L-G-A-N-I-T-C-A-D-N-T-G-A-R-S-I-S-L-I-D-V-K-A-W-H-G-K-A-R-R-I-P-A-A-G-V-G-D-M-F-M-A-S-V-K-K-G-T-P-E-M-R-S-K-V-V-Y-A-V-V-I-R-Q-K-R-P-Y-R-R-P-D-G-T-M-V-Q-F-E-D-N-A-A-V-L-V-T-P-D-G-E-V-R-G-S-E-I-K-G-P-V-A-R-E-A-A-E-R-W-P-R-I-A-A-I-A-S-I-I-V"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-S-Q-V-K-L-K-P-K-K-K-Y-G-H-I-D-G-C-V-R-C-G-R-K-R-G-I-V-R-R-Y-G-L-H-L-C-R-Q-C-F-R-E-T-A-R-Q-L-G-F-E-K-Y-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-K-N-D-T-L-N-D-V-I-N-S-I-K-N-A-S-R-L-G-K-R-E-I-I-A-E-P-A-A-K-L-I-G-K-V-L-K-V-M-Q-D-Y-N-Y-I-K-S-F-E-V-I-D-E-S-R-G-G-K-F-K-I-V-L-N-T-T-I-N-N-C-G-V-I-K-P-R-F-P-V-K-N-E-N-L-E-K-Y-E-A-R-Y-L-P-A-E-D-F-G-I-L-I-L-T-T-T-K-G-V-M-S-N-I-E-A-R-K-L-G-I-G-G-K-L-L-A-Y-V-Y"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-I-N-W-K-E-A-R-S-I-K-I-P-D-G-F-K-V-S-I-S-G-T-T-V-T-I-S-Y-G-G-K-T-I-S-K-N-F-A-N-N-Y-V-K-L-V-E-D-G-S-T-I-K-I-N-A-S-K-N-N-S-M-V-R-G-I-V-G-T-W-A-S-E-I-N-N-M-I-K-G-L-K-D-G-F-Q-Y-E-M-K-I-D-Y-S-H-F-P-M-R-V-S-V-K-G-K-T-V-V-I-E-N-F-F-G-E-R-S-P-R-T-A-E-I-V-G-D-T-T-V-T-V-K-G-D-R-V-Y-I-A-G-I-S-K-K-D-V-G-E-T-A-A-N-I-E-R-S-T-I-I-K-G-F-D-P-R-V-F-Q-D-G-I-Y-L-I-S-K-G-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-M-V-F-K-R-K-E-A-G-I-T-D-Y-S-K-R-L-K-L-L-K-S-R-E-K-R-F-I-V-R-I-T-G-K-G-V-I-A-Q-V-A-E-Y-S-D-I-G-D-R-I-L-F-T-V-T-D-K-T-L-A-K-Y-G-V-D-L-R-G-N-N-I-Q-V-C-Y-L-V-G-Y-I-A-G-I-E-S-E-K-N-G-V-E-S-A-V-L-D-T-G-R-R-K-F-R-K-G-G-R-I-A-A-C-L-K-G-F-T-D-A-G-I-E-V-P-H-G-E-D-V-F-P-D-K-K-R-I-D-G-K-H-L-K-S-P-V-K-I-S-E-I-V-K-N-F-K-K-M-E-E-K-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-V-R-E-R-T-K-K-L-R-G-G-H-Y-G-R-G-F-K-A-G-R-G-K-G-K-K-G-G-S-G-N-A-G-M-G-K-H-K-W-I-W-M-V-K-Y-D-P-L-H-F-G-G-K-G-F-T-S-H-H-I-S-Q-V-E-V-P-I-N-L-G-D-V-E-Y-M-Y-E-S-L-K-R-D-G-F-V-R-E-E-N-G-E-I-I-V-D-L-R-A-A-G-Y-D-K-L-L-G-N-G-N-F-T-V-K-S-T-I-I-I-D-K-A-T-E-K-A-I-S-K-L-S-A-I-G-S-K-I-E-N-D-G-S-S-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-S-N-G-T-A-V-M-G-K-I-N-N-K-K-T-H-I-R-C-R-R-C-G-H-H-T-Y-N-V-R-T-K-R-C-S-H-C-G-F-P-A-P-R-I-R-S-Y-R-W-A-K-A-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-M-P-K-K-I-M-T-Y-C-P-Y-C-K-K-H-T-S-H-S-V-E-R-V-R-K-R-K-A-S-E-L-K-A-G-Q-R-R-F-R-R-V-T-S-G-Y-G-G-F-P-R-P-K-F-E-G-R-E-K-P-T-K-R-I-A-L-R-L-V-C-D-E-C-H-K-A-I-T-P-P-G-I-R-A-K-K-F-E-I-V-E-A"} +{"text": "### FUNCTION Involved in ribosome biogenesis ### SEQUENCE -M-K-S-L-I-R-K-C-P-R-C-H-A-Y-T-M-E-E-K-C-P-K-C-G-S-D-T-Y-I-A-V-P-P-R-Y-S-P-V-D-R-F-R-K-Y-R-I-E-E-L-R-G-E-I-D-G-E-N-S-G-D-Q-I"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-V-E-P-N-I-S-A-Y-L-Q-N-Q-L-R-Q-A-Q-E-L-E-E-N-I-E-K-L-A-T-Q-R-Y-Q-L-D-L-S-L-K-E-M-Q-K-T-L-D-E-L-N-K-L-D-D-N-T-P-I-Y-R-T-V-G-S-I-L-Y-R-V-Q-D-K-K-K-L-V-D-E-L-D-E-Q-I-E-L-T-K-I-R-L-S-T-L-E-K-Q-Q-K-S-L-E-E-K-Y-K-E-L-Q-N-A-I-R-D-R-Y-N-Q-E-N-K-K-G-A-T-S"} +{"text": "### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-R-I-V-V-G-I-S-G-A-S-G-I-P-Y-A-V-R-F-L-E-N-L-R-G-H-D-T-Y-L-V-I-S-E-A-A-K-K-V-I-Q-Y-E-S-D-E-N-I-E-Y-I-R-S-L-A-S-H-N-Y-E-D-D-D-F-S-A-P-I-S-S-G-S-F-L-F-D-S-M-V-I-V-P-C-S-I-T-T-I-S-K-I-A-A-G-I-S-D-T-L-I-T-R-A-A-A-V-S-L-K-E-R-R-R-L-I-V-V-P-R-E-M-P-L-S-T-I-D-L-K-N-M-T-Y-L-S-E-N-G-V-I-V-A-P-A-S-P-G-F-Y-T-K-P-K-S-V-D-D-M-V-A-F-V-V-S-R-I-L-D-L-V-G-V-G-N-D-L-I-K-R-W"} +{"text": "### FUNCTION Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A ### SEQUENCE -M-T-E-S-A-R-Q-K-I-K-G-R-N-G-R-V-V-D-P-D-E-V-R-D-L-S-V-D-H-P-V-A-A-V-G-D-V-T-A-Y-N-L-R-K-V-N-A-R-V-L-L-E-I-V-D-L-R-T-K-R-S-D-L-L-F-A-H-E-E-G-S-I-V-I-R-N-D-P-G-T-I-S-F-D-L-I-R-A-I-Q-S-A-L-L-S-D-K-K-T-R-I-E-V-I-G-E-E-D-L-A-V-L-P-I-I-Y-Y-A-D-L-D-T-V-I-A-Y-G-I-P-D-V-G-M-A-I-L-T-V-D-F-D-L-K-C-H-V-C-E-V-L-S-E-M-A-I-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-Q-P-T-P-S-E-Y-A-R-T-P-V-R-I-E-M-Q-R-S-K-E-R-N-S-M-V-Y-K-E-M-Y-N-D-A-Q-R-K-Y-S-E-A-L-D-R-I-S-K-L-T-D-A-Y-L-R-E-K-A-E-V-E-N-F-I-K-I-K-D-R-E-V-E-M-S-K-K-N-A-N-E-K-L-L-K-D-F-L-P-V-L-D-S-I-D-A-A-I-Q-A-E-K-D-N-N-L-I-R-I-R-D-Q-M-L-G-V-L-S-R-Y-G-L-K-P-I-K-A-E-G-S-K-F-D-P-Y-L-H-E-V-V-G-V-T-A-D-G-E-D-G-M-V-K-Y-E-V-Q-R-G-Y-T-L-N-D-G-V-L-R-T-S-K-V-I-V-V-K-R"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-A-R-D-V-E-A-Q-L-N-Y-I-E-S-L-I-S-S-V-D-S-Q-I-D-T-L-N-K-A-M-I-E-V-Q-S-T-I-D-L-L-S-N-G-D-L-A-S-S-P-E-K-L-I-S-I-G-S-G-L-F-A-K-G-N-I-T-I-D-E-D-L-I-V-P-I-G-S-G-I-Y-V-A-E-T-K-E-R-S-V-E-R-L-K-K-N-L-E-D-I-K-A-S-I-Q-K-L-L-D-Q-R-K-T-L-V-D-Q-Y-N-T-V-Y-A-T-E-A-T-R-N-V-K"} +{"text": "### FUNCTION Functions by promoting the formation of the first peptide bond ### SEQUENCE -M-S-W-Q-E-A-E-V-R-E-L-K-V-G-R-Y-I-L-I-D-D-A-P-C-K-I-V-E-I-T-M-S-K-P-G-K-H-G-E-A-K-G-R-I-V-A-I-G-V-F-D-N-Q-K-R-S-V-V-Y-P-V-K-H-K-V-K-I-P-I-I-E-K-K-N-A-Q-V-L-S-V-Q-N-N-E-V-Q-L-M-D-S-E-T-F-E-T-F-V-L-P-L-D-P-E-I-A-D-K-I-K-P-G-M-E-V-P-Y-W-E-T-M-G-M-R-K-I-M-L-Q-N"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-K-G-S-A-N-N-V-K-V-N-Q-D-A-G-K-S-Q-P-E-K-K-E-N-K-D-F-Q-Y-I-V-R-I-A-N-K-D-L-N-G-E-R-L-L-P-L-A-L-S-D-L-K-G-I-G-E-R-L-G-Y-V-I-A-E-R-L-D-L-P-I-D-K-K-I-G-E-L-K-E-E-Q-L-E-K-L-R-E-Y-V-E-A-K-E-Y-D-L-P-E-W-L-L-N-H-R-R-E-P-V-T-G-K-N-L-N-L-V-S-T-D-L-E-I-Q-V-Q-E-D-I-N-L-M-K-K-I-R-S-Y-K-G-I-R-H-E-K-G-K-K-V-R-G-Q-R-T-R-S-N-G-R-K-G-L-S-I-G-V-V-R-K-K-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-G-D-P-K-F-H-H-K-K-Y-S-T-P-R-H-P-W-E-K-E-R-I-D-E-E-N-K-I-V-V-K-Y-G-L-K-N-K-K-E-I-W-R-S-E-A-L-L-S-S-I-R-S-Q-A-R-D-L-R-A-R-L-R-T-N-D-V-N-A-Q-K-Q-L-E-R-M-I-K-R-L-N-R-Y-K-L-L-S-E-N-A-T-L-D-D-V-L-S-L-T-V-E-N-I-L-D-R-R-L-Q-T-I-V-F-R-K-N-L-A-I-S-V-R-Q-A-R-Q-L-I-T-H-G-H-I-S-V-A-G-R-R-V-T-V-P-G-M-L-V-E-A-K-D-E-D-T-I-A-Y-E-E-N-S-P-V-A-N-E-L-H-P-I-R-Q-A-L-L-A-P-A-Q-R-S-A-E-M-K-E-G-Q-G-E-A-S-E-E-G-E-T-D-E"} +{"text": "### FUNCTION Located on the platform of the 30S subunit ### SEQUENCE -M-R-Q-M-N-K-T-G-I-A-H-I-Y-A-S-Q-N-N-T-I-I-H-V-T-D-P-T-G-A-E-T-I-A-M-V-S-G-G-M-V-V-K-N-D-R-D-Q-A-S-P-Y-A-A-M-K-A-A-D-M-V-S-E-A-L-K-E-K-E-I-T-D-L-I-I-K-V-R-A-P-G-G-N-K-S-K-I-P-G-P-G-A-Q-A-A-I-R-A-L-S-R-A-G-L-K-I-V-R-I-E-E-V-T-P-I-P-H-D-G-T-K-K-K-G-G-K-R-G-R-R-V"} +{"text": "### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-I-P-L-A-I-K-I-G-I-T-G-P-V-G-S-I-K-S-E-A-L-Q-K-I-I-D-M-L-K-N-D-N-L-N-V-Q-G-V-L-V-S-K-V-T-N-N-G-K-L-T-G-Y-T-I-E-D-I-E-S-K-R-K-A-Q-F-C-F-D-N-F-V-S-R-V-K-I-D-K-L-G-V-D-T-K-I-L-E-E-I-L-I-P-S-L-Q-K-A-R-E-T-A-D-V-I-V-I-D-E-I-G-K-L-E-N-T-T-K-K-V-H-A-E-I-E-E-T-L-K-C-G-K-P-L-I-V-T-L-H-K-R-S-R-N-P-V-L-Q-E-I-K-S-L-E-G-V-R-V-F-D-I-T-P-I-N-K-N-I-L-P-F-K-V-M-H-V-L-K-G-E-E"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-A-E-E-N-I-I-F-V-G-K-K-P-T-M-N-Y-V-L-A-V-V-T-Q-F-N-N-N-A-N-K-I-I-I-K-A-R-G-K-T-I-S-K-A-V-D-V-A-E-I-T-R-H-K-F-I-P-D-A-K-Y-E-E-I-K-L-D-T-E-T-L-Q-G-E-R-G-S-S-N-V-S-S-I-E-I-T-L-S-R"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently ### SEQUENCE -M-D-S-D-D-N-R-T-L-S-Y-E-V-V-D-H-E-S-D-I-G-V-I-V-Y-G-K-T-Y-E-E-L-F-S-N-A-V-Y-A-M-A-D-L-I-V-D-V-S-R-L-K-E-N-R-K-M-H-E-V-I-T-G-K-T-P-E-D-I-M-V-N-L-L-S-R-V-L-F-Y-L-D-T-Y-Y-I-L-Y-Y-R-I-T-S-K-Y-S-D-G-E-L-D-A-Y-F-Y-G-S-E-I-P-E-G-I-E-Y-R-N-V-I-K-A-V-T-Y-S-D-L-A-V-K-P-E-E-G-Y-A-K-I-I-F-D-L"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-E-K-T-L-R-I-S-K-I-R-D-G-T-V-I-D-H-V-P-S-G-K-G-I-R-V-I-G-V-L-G-V-H-E-D-V-N-Y-T-V-S-L-A-I-H-V-P-S-N-K-M-G-F-K-D-V-I-K-I-E-N-R-F-L-D-R-N-E-L-D-M-I-S-L-I-A-P-N-A-T-I-S-I-I-K-N-Y-E-I-S-E-K-F-Q-V-E-L-P-S-R-L-I-G-V-L-K-C-K-N-Q-N-C-I-T-N-T-R-E-P-V-E-S-E-F-E-I-V-S-K-H-P-L-V-I-R-C-V-Y-C-E-R-T-M-G-E-K-D-I-F-T"} +{"text": "### FUNCTION Broad-specificity nucleoside monophosphate kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-I-C-I-S-G-I-P-G-T-G-K-S-T-I-C-N-L-L-N-D-L-G-Y-T-C-V-E-G-N-A-L-A-V-K-Y-G-C-L-S-G-D-E-V-D-V-D-C-L-S-D-R-M-R-S-D-N-F-K-G-I-V-A-A-H-Y-A-H-L-L-P-C-N-I-V-I-I-L-E-A-D-E-S-A-L-R-Q-R-M-M-D-R-G-Y-S-P-E-K-I-D-E-N-L-D-A-Q-R-S-D-T-I-Y-A-E-S-L-E-R-L-P-A-N-R-I-F-R-I-R-N-A-D-L-N-V-A-L-S-D-I-L-R-I-I-G-G-R-N-G"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-G-D-V-L-V-T-L-K-I-L-P-K-D-T-D-A-D-I-K-S-I-E-D-Q-V-K-R-N-I-E-G-L-C-S-I-N-R-M-D-E-V-D-I-G-F-G-L-K-Y-I-K-L-E-I-I-V-Q-D-K-E-G-E-I-D-R-V-E-N-S-I-S-S-I-E-G-V-G-E-I-S-T-E-N-V-S-L-I"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-V-I-D-A-S-G-A-I-Y-G-R-L-S-A-Y-V-A-K-R-L-L-E-G-E-E-I-T-I-V-N-A-S-K-A-V-I-T-G-N-K-E-F-I-I-E-K-F-K-E-R-L-D-I-G-S-V-R-K-G-P-Y-Y-P-K-T-P-E-N-I-L-R-R-S-I-G-D-M-L-P-K-K-I-T-K-G-K-E-A-L-A-R-C-R-V-Y-R-N-T-P-P-D-I-E-K-E-K-V-E-K-V-D-G-V-V-T-D-K-V-S-G-I-I-T-L-G-D-L-S-K-E-L-G-G-Y"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-Q-S-V-K-T-M-V-E-G-G-K-A-T-T-G-P-P-I-G-P-A-L-G-P-L-G-L-N-V-A-Q-V-V-K-E-I-N-E-K-T-K-E-F-Q-G-M-R-V-P-V-T-I-T-V-V-D-P-E-T-K-K-Y-E-I-T-V-G-I-P-P-T-S-A-L-L-K-K-K-L-G-I-E-K-G-A-A-K-R-K-E-A-I-A-G-N-A-T-L-D-Q-I-V-D-V-A-K-T-K-M-A-S-M-L-A-S-D-L-K-A-A-T-L-E-V-L-G-T-C-V-S-M-G-I-N-V-D-G-K-D-P-K-E-V-Q-R-Q-I-K-A-G-E-I-S-I"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-S-E-R-E-K-I-T-I-E-N-I-V-A-S-T-S-L-A-E-H-L-D-L-S-R-I-A-L-A-L-D-G-S-E-Y-E-P-E-Q-F-P-G-L-I-Y-R-L-Q-E-P-K-T-A-V-L-I-F-R-S-G-K-V-N-C-T-G-A-K-N-I-E-D-V-K-R-T-I-K-I-I-I-D-K-L-K-A-A-D-I-E-V-Y-D-D-P-Q-I-I-V-Q-N-I-V-A-V-Y-D-L-E-S-E-L-N-L-T-D-I-A-M-S-L-G-L-E-N-V-E-Y-E-P-E-Q-F-P-G-L-V-Y-R-V-E-E-P-R-V-V-L-L-L-F-G-S-G-K-V-V-C-T-G-A-K-E-E-S-E-I-E-Q-A-V-I-K-V-K-K-E-L-Q-K-V-G-L-I"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-K-K-M-V-I-A-V-R-K-D-L-D-M-G-K-G-K-I-A-A-Q-V-A-H-A-A-V-T-C-A-I-R-S-M-K-I-N-R-D-V-F-N-E-W-Y-D-E-G-Q-R-K-I-V-V-K-V-N-D-L-D-E-I-M-E-I-K-R-M-A-D-S-M-G-I-V-N-E-I-V-Q-D-R-G-Y-T-Q-V-E-P-G-T-I-T-C-I-G-L-G-P-D-E-E-E-K-L-D-K-I-T-G-K-Y-K-L-L"} +{"text": "### FUNCTION Catalyzes the formation of CDP-2,3-bis- and CTP This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-Q-S-I-I-L-F-I-P-A-L-I-A-N-S-G-A-V-I-T-G-G-H-F-I-I-D-R-G-K-K-F-I-D-G-R-R-I-L-G-N-G-K-T-L-S-G-Y-A-G-G-I-A-I-G-T-V-T-G-F-I-I-Y-L-I-S-T-L-F-N-Y-A-L-G-T-Y-G-T-L-A-E-A-I-I-I-P-F-I-M-A-T-G-S-L-T-G-D-I-A-G-S-F-V-K-R-R-I-G-I-D-R-G-G-K-G-G-L-L-D-Q-W-P-F-A-L-M-A-F-L-F-L-Y-I-F-E-R-P-F-F-M-Y-H-Y-F-Y-V-T-M-I-V-I-L-V-I-V-P-P-I-H-R-A-V-N-I-I-G-Y-K-M-H-K-K-D-V-P-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center ### SEQUENCE -M-L-F-N-K-Y-D-V-N-A-V-E-I-H-D-P-G-M-V-K-Y-I-N-V-K-S-A-L-N-L-H-T-G-G-R-F-S-S-Y-Y-A-G-K-I-N-M-N-V-V-E-R-L-I-N-K-L-M-R-S-E-K-W-T-G-K-K-Y-S-A-Y-K-I-T-E-E-A-F-Q-I-I-A-E-K-T-K-Q-N-P-L-Q-I-L-I-N-A-I-E-N-A-G-P-R-E-E-V-T-R-L-K-Y-G-G-I-A-V-P-K-S-V-D-V-S-P-S-R-R-V-D-E-A-L-R-N-I-A-T-G-A-T-N-A-S-F-K-S-K-K-S-I-V-N-C-L-A-D-E-I-M-A-A-A-R-N-D-P-T-S-F-A-I-S-K-K-E-E-I-E-R-V-A-Q-S-A-R"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-G-N-G-I-N-A-G-R-K-L-L-E-N-R-K-K-F-R-W-S-D-R-D-Y-K-R-R-V-L-Q-L-K-R-K-S-D-P-L-E-G-A-P-Q-A-K-G-I-A-I-E-K-V-G-I-E-A-K-Q-P-N-S-A-I-R-K-C-V-K-V-Q-L-I-K-N-G-R-Q-I-T-A-F-A-V-G-D-G-A-I-N-Y-I-D-E-H-D-E-V-T-V-E-G-I-G-G-R-M-G-R-S-K-G-D-I-P-G-V-R-Y-K-V-V-A-V-N-G-I-S-L-K-E-L-V-K-G-R-K-E-K-T-V-R"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-G-G-L-E-E-D-L-L-R-V-G-A-I-K-F-G-D-F-V-L-T-S-G-K-R-S-T-Y-Y-V-D-I-K-E-A-A-T-D-P-S-V-L-R-K-I-A-S-E-F-S-G-M-I-R-S-S-K-I-A-G-M-E-L-G-A-V-P-L-I-V-A-T-A-L-Q-M-S-I-P-Y-I-I-V-R-K-E-R-S-H-G-T-M-S-L-L-V-G-K-F-E-K-G-E-E-I-D-V-I-E-D-V-V-T-T-G-N-S-V-L-K-A-V-N-T-L-R-E-N-G-A-V-V-K-R-A-Y-C-V-V-D-R-E-E-G-G-S-D-L-L-K-E-N-G-I-D-L-H-P-I-I-R-I-S-Q-V-K-G-F-R-K"} +{"text": "### FUNCTION May be involved in maturation of the 30S ribosomal subunit ### SEQUENCE -M-V-S-V-K-Y-V-P-S-D-L-L-I-N-Y-V-S-E-K-L-K-S-E-K-K-I-A-E-P-D-W-S-K-Y-V-K-T-G-I-S-R-E-K-S-P-V-N-R-D-W-I-Y-V-R-A-A-A-M-L-R-K-L-Y-I-N-G-Y-L-G-I-S-R-M-S-S-E-Y-G-G-K-V-D-R-G-S-K-R-Y-H-A-A-Q-G-S-R-S-I-I-R-Y-L-F-H-E-L-E-K-A-G-Y-V-Q-K-T-P-K-G-R-S-L-S-P-Q-G-M-S-L-L-D-N-A-S-K-D-I-I-K-Q-L-A-E-K-D-P-A-F-Q-K-F-I"} +{"text": "### FUNCTION Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in Mjannaschii 16S rRNA It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3- ### SEQUENCE -M-I-Y-I-Y-F-I-Y-L-K-Q-D-D-P-K-K-S-T-M-R-K-L-E-R-F-G-I-A-R-R-I-S-P-G-G-A-R-D-K-L-M-L-T-R-S-A-D-T-V-L-S-K-N-D-R-F-I-A-E-R-S-G-I-C-V-I-E-G-S-W-N-R-E-D-T-F-A-G-L-R-F-P-Y-G-R-R-L-P-K-L-L-A-A-N-P-V-N-Y-G-K-L-E-K-L-S-S-I-E-A-V-A-A-A-L-Y-I-M-G-F-Q-D-D-A-S-A-I-L-S-K-Y-T-W-G-Q-N-F-L-Q-L-N-K-N-P-L-D-E-Y-R-E-A-D-P-E-K-I-P-E-I-E-N-A-Y-F"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-E-S-C-I-T-V-I-G-E-R-D-V-V-L-G-F-R-L-L-G-I-Q-H-T-I-I-A-E-G-K-D-L-L-K-K-F-L-E-V-F-Q-N-P-Q-C-N-I-I-I-V-S-E-N-V-K-N-M-M-D-K-R-T-L-R-S-V-E-I-S-S-K-P-L-V-V-F-I-P-L-P-G-V-R-E-E-E-T-I-E-E-M-A-K-R-I-L-G-I-D-I-G-N-V"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-L-E-E-V-L-K-D-I-E-R-D-K-E-E-K-K-K-E-I-A-D-A-A-S-R-E-T-A-K-I-E-K-E-R-E-E-K-I-Q-I-L-Q-R-E-Y-E-N-R-M-R-E-E-G-S-R-L-Y-N-S-I-I-D-K-A-N-V-E-A-R-N-I-V-R-M-R-V-Q-E-I-L-D-Q-Y-G-A-K-A-D-E-L-I-K-N-L-A-K-T-K-E-Y-D-D-V-L-K-K-M-I-E-V-S-R-K-A-L-G-P-D-C-I-V-K-V-N-T-A-D-K-G-R-I-S-D-G-N-I-K-F-E-D-I-D-P-Y-G-G-V-L-A-T-S-R-D-G-K-I-E-L-D-L-R-I-S-S-I-R-R-D-I-L-E-R-F-K-V-R-L-Y-S-M-I-E-D"} +{"text": "### FUNCTION Probable zinc metalloprotease whose natural substrate is unknown ### SEQUENCE -M-R-V-D-I-V-P-V-G-D-V-P-A-H-V-K-R-Q-A-S-S-S-L-R-S-V-Y-D-C-E-V-V-V-A-S-E-Q-D-V-P-T-A-A-Y-D-E-A-R-S-Q-Y-R-A-A-E-F-I-D-T-A-T-R-A-T-S-G-D-K-T-I-A-I-T-P-H-D-L-F-Y-R-R-R-N-Y-V-F-G-L-A-Y-L-D-G-R-G-C-V-V-S-T-Y-R-L-Q-T-S-S-D-G-G-F-S-N-R-S-S-S-D-V-F-D-D-R-V-R-K-E-V-V-H-E-L-G-H-T-L-G-L-E-H-C-D-N-N-R-C-A-M-N-F-S-P-T-V-R-E-V-D-R-K-E-E-N-L-C-G-S-C-Q-R-T-V-F"} +{"text": "### FUNCTION Involved in protein export The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex ### SEQUENCE -M-S-S-G-Q-N-S-G-G-L-M-S-S-A-G-L-V-R-Y-F-D-S-E-D-S-N-A-L-Q-I-D-P-R-S-V-V-A-V-G-A-F-F-G-L-V-V-L-L-A-Q-F-F-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-Y-E-R-G-A-F-V-A-D-H-V-E-P-V-A-D-D-Q-I-Q-P-N-G-V-D-L-T-V-D-A-V-L-E-Q-T-E-P-G-R-I-D-T-D-G-K-T-I-G-D-R-S-P-V-T-P-T-A-D-E-D-S-T-D-T-T-V-T-I-Q-P-G-T-Y-I-L-Q-Y-A-E-T-I-T-I-P-E-N-H-V-G-F-V-Y-P-R-S-S-L-M-R-N-S-C-M-L-H-S-A-V-W-D-A-G-Y-T-G-R-G-E-G-L-F-E-V-H-H-E-I-T-I-A-R-G-A-R-V-A-Q-L-V-L-A-T-G-D-H-E-N-T-Y-D-G-S-Y-Q-H-E-R-T-D-T-R-P-G-E"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-S-L-G-G-G-G-Q-Q-Q-L-Q-Q-L-S-Q-E-I-Q-A-I-E-E-E-V-E-E-L-E-A-D-V-A-S-L-R-Q-E-Q-T-E-I-E-E-A-K-E-A-L-D-V-L-E-T-G-A-T-V-Q-V-P-L-G-G-D-A-Y-V-R-A-E-V-K-D-M-D-E-V-V-V-S-L-G-G-G-Y-A-A-E-Q-D-S-D-A-A-A-S-V-L-D-E-K-K-A-T-I-D-G-R-I-D-D-V-Q-A-E-I-A-D-L-S-E-E-A-E-Q-L-E-Q-Q-A-Q-Q-A-Q-Q-Q-M-M-Q-Q-Q-M-Q-A-Q-Q-Q-P-Q-D-G-E-Q"} +{"text": "### FUNCTION Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP ### SEQUENCE -M-Y-I-G-R-F-V-V-V-G-P-S-V-A-A-Y-R-V-S-S-R-S-F-P-N-R-K-L-I-E-R-P-A-G-L-T-V-V-P-T-A-D-A-E-E-T-T-N-P-Y-V-S-Y-N-C-V-R-T-A-G-G-H-A-V-V-G-N-G-S-H-V-D-P-I-T-E-K-V-E-R-G-Y-P-P-R-D-A-L-T-E-A-L-L-A-M-D-Y-E-K-D-D-Y-D-T-P-R-I-A-G-V-L-A-P-D-G-T-A-Y-V-G-I-V-R-A-D-A-V-L-V-R-A-V-E-E-P-T-L-V-A-T-Y-E-K-D-A-P-E-A-I-G-F-D-A-A-T-A-A-D-A-A-R-E-A-Y-S-A-A-F-E-H-A-V-C-A-A-G-V-S-R-R-G-V-G-D-G-Y-D-T-A-V-V-N-D-P"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-T-D-P-K-E-T-I-N-I-E-N-V-V-A-S-T-G-I-G-Q-E-L-D-L-Q-S-V-A-M-D-L-E-G-A-D-Y-D-P-E-Q-F-P-G-L-V-Y-R-T-Q-D-P-K-S-A-A-L-I-F-R-S-G-K-I-V-C-T-G-A-K-S-T-D-D-V-H-E-S-L-R-I-V-F-D-K-L-R-E-L-S-I-K-V-E-D-D-P-E-I-V-V-Q-N-I-V-T-S-A-D-L-G-R-Q-L-N-L-N-A-I-A-I-G-L-G-L-E-N-I-E-Y-E-P-E-Q-F-P-G-L-V-Y-R-L-D-D-P-E-V-V-A-L-L-F-G-S-G-K-L-V-I-T-G-G-K-E-P-K-D-A-E-H-A-V-D-K-I-T-S-R-L-E-E-L-G-L-L-D"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-S-D-D-G-G-G-R-K-N-L-R-M-P-E-D-D-E-V-F-A-E-V-T-D-M-L-G-A-N-R-V-Q-V-R-C-A-D-G-E-E-R-T-A-R-I-P-G-R-M-Q-K-R-I-W-I-R-E-D-D-I-V-L-V-E-P-W-D-W-Q-D-D-K-A-D-V-T-W-R-Y-E-K-S-D-A-D-Q-L-R-E-E-G-H-I-E"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-L-E-T-V-V-E-D-I-R-D-E-A-R-E-R-A-K-E-I-R-A-D-A-D-E-R-A-D-E-I-V-A-E-A-E-A-D-A-D-D-I-I-A-D-A-E-A-E-V-T-A-E-I-D-Q-E-R-E-Q-Q-L-S-S-A-E-L-E-A-K-Q-M-R-L-E-A-R-R-D-A-L-Q-S-V-R-S-A-V-E-D-R-I-V-A-L-D-G-D-E-R-E-E-L-T-R-E-L-L-D-A-A-S-T-E-F-D-G-A-D-T-V-R-V-F-G-R-A-D-D-E-A-L-I-S-E-I-L-D-D-Y-D-G-Y-E-Y-A-G-E-Y-D-C-L-G-G-V-V-V-E-S-D-A-S-R-I-R-V-N-N-T-F-D-S-I-L-A-D-A-W-E-N-N-L-K-A-I-S-A-R-L-F-D-E-E-Q"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-Q-E-I-A-V-I-G-S-P-A-F-T-T-G-F-Q-L-A-G-V-R-K-V-E-N-V-A-D-D-E-K-D-D-D-L-D-A-A-V-E-A-V-L-A-D-E-D-V-G-I-A-V-M-H-D-D-D-L-A-H-L-S-R-G-V-R-Q-S-V-E-A-S-V-E-P-T-F-V-T-I-G-G-G-A-S-G-A-S-G-L-R-D-Q-I-K-R-A-I-G-I-D-L-M-D-D-D-D-D-A-S-A-A-D-T-E-A-G-D"} +{"text": "### FUNCTION Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in Mjannaschii 16S rRNA It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3- ### SEQUENCE -M-E-L-H-V-R-Y-E-G-D-D-D-P-E-K-C-T-A-R-K-L-A-R-F-D-L-A-A-L-H-R-T-G-R-E-T-P-A-G-V-V-L-N-P-H-A-E-R-A-L-S-P-A-D-D-T-D-M-L-V-A-L-D-C-S-W-E-T-A-G-R-A-M-F-E-I-D-G-E-H-R-A-L-P-F-L-V-A-A-N-P-V-N-Y-G-Q-P-F-Q-L-N-T-V-E-A-F-A-G-A-L-A-I-L-G-R-W-E-R-A-E-E-L-L-S-K-F-T-W-G-H-T-F-L-E-L-N-E-E-P-L-R-R-Y-A-D-C-E-D-S-S-E-V-V-A-V-Q-Q-A-Y-L-D-A-G-E-D"} +{"text": "### FUNCTION Specifically catalyzes the N1-methylation of pseudouridine at position 54 in tRNAs ### SEQUENCE -M-R-Q-F-V-V-L-G-H-D-A-P-T-T-P-D-F-P-L-D-D-L-P-G-A-A-G-R-L-D-V-L-C-R-C-V-S-A-A-L-F-V-S-H-G-I-R-D-D-V-E-V-F-L-V-L-G-D-E-V-T-V-R-I-D-A-G-A-V-Q-Y-M-H-P-D-E-R-N-V-A-G-L-L-K-Q-A-L-D-A-K-T-E-A-I-G-H-Q-E-A-S-S-S-P-G-I-H-V-S-K-R-G-F-E-A-V-L-D-A-V-S-G-P-V-V-A-L-H-E-D-G-D-A-L-A-A-V-D-P-L-A-D-P-V-F-V-L-S-D-H-R-D-F-T-A-A-E-A-S-L-L-A-D-A-S-D-H-R-V-R-V-G-P-T-V-L-H-A-D-H-A-I-T-V-A-H-N-H-L-D-T-A-G-F-D-A-Y"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-G-I-P-L-R-I-D-A-R-S-T-A-L-V-A-V-G-G-A-V-G-A-V-L-R-Y-T-V-A-Q-A-I-A-G-P-L-G-T-L-A-A-N-A-A-G-S-L-A-L-G-A-L-A-Y-E-A-A-A-T-D-S-V-L-S-A-D-A-H-T-L-L-G-T-G-C-L-S-A-F-T-T-Y-S-T-F-A-V-Q-T-A-G-L-A-P-R-W-M-A-A-N-V-A-T-T-Y-A-L-G-F-A-G-V-L-V-G-R-A-I-A-A-T-A-R-G-D-R-R"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-T-G-A-V-A-P-P-A-V-L-V-A-A-G-G-A-L-G-A-V-L-R-W-R-V-V-A-A-T-P-T-T-E-Y-P-A-G-T-L-V-V-N-V-V-G-S-F-V-L-A-A-L-T-F-A-A-A-D-A-D-T-M-L-L-F-G-T-G-A-C-G-A-F-T-T-F-A-S-F-S-V-D-V-V-A-L-V-D-A-D-R-P-V-A-A-A-G-H-A-L-G-N-L-L-G-A-G-L-A-V-A-L-A-W-L-L-V-A"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-S-D-E-S-G-R-R-N-L-R-M-P-N-D-D-E-V-F-A-V-V-K-R-H-D-G-G-N-H-V-T-L-Q-C-E-D-G-K-E-R-M-G-R-I-P-G-R-M-K-Y-R-T-W-I-N-E-G-D-V-V-L-A-E-P-W-D-W-Q-D-E-K-A-N-V-E-W-R-Y-S-D-Q-D-A-D-Q-L-R-E-E-G-H-I-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-S-D-L-S-A-Q-K-R-L-A-A-D-V-L-D-V-G-E-N-R-V-W-F-D-P-D-A-Q-S-E-I-A-D-A-I-T-R-E-D-I-R-E-L-V-A-D-G-T-I-D-A-E-D-T-Q-G-N-S-R-G-R-A-R-E-R-D-A-K-E-S-Y-G-H-K-K-G-A-G-S-R-K-G-K-A-G-A-R-Q-N-E-K-R-E-Y-V-A-G-I-R-A-Q-R-Q-Q-L-R-E-L-R-D-D-G-T-L-S-P-A-Q-Y-R-E-M-Y-N-M-A-N-G-G-E-F-D-S-V-R-R-L-T-N-Y-V-E-E-N-Y-G-D-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-A-N-D-P-L-S-D-A-L-S-G-I-D-N-A-E-S-V-G-H-L-T-H-T-V-A-P-A-S-N-M-V-G-S-V-L-E-V-F-Y-D-R-G-Y-I-D-G-F-E-F-V-D-N-G-K-A-G-R-F-E-V-E-L-K-G-A-I-N-E-C-G-P-V-N-P-R-Y-S-V-G-A-D-G-F-E-Q-W-E-K-R-Y-L-P-A-R-D-Y-G-S-L-V-V-T-T-S-H-G-I-M-S-H-Y-E-A-R-E-A-G-I-G-G-Q-V-I-A-Y-V-Y"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-S-E-T-D-G-E-A-E-E-T-G-Q-T-H-E-C-R-R-C-G-R-E-Q-G-L-V-G-K-Y-D-I-W-L-C-R-Q-C-F-R-E-I-A-R-S-M-G-F-K-K-Y-S"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-E-Q-P-H-K-Q-R-T-R-T-K-R-A-S-L-H-E-K-Q-D-Q-V-R-A-T-L-S-E-E-L-R-E-E-Y-G-Q-R-N-V-R-V-N-V-G-D-T-V-E-V-M-R-G-D-D-A-G-E-D-G-E-V-T-D-V-D-L-R-D-A-E-V-F-V-E-G-V-T-V-E-A-A-D-G-E-E-T-P-R-P-V-E-S-S-N-L-R-V-T-D-L-D-L-D-D-D-M-R-V-E-R-L-E-G-D-N-E"} +{"text": "### FUNCTION Part of the energy-coupling factor transporter complex CbiMNOQ involved in cobalt import ### SEQUENCE -M-N-R-W-L-A-A-G-G-I-L-L-G-A-L-V-V-F-S-F-V-S-A-G-A-W-G-G-A-D-G-V-A-G-D-T-I-T-T-I-N-P-S-Y-E-P-W-F-Q-S-L-W-T-P-P-S-G-E-I-E-S-L-L-F-S-I-Q-A-A-V-G-G-I-I-I-G-Y-Y-L-G-R-D-R-P-R-G-Q-S-Q-D-M-G-S-D-L-P"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-F-D-V-P-D-D-L-Q-Y-L-E-S-H-E-W-I-D-P-A-T-G-R-V-G-I-S-E-F-A-Q-D-E-L-G-D-V-V-F-V-E-L-P-S-V-G-D-A-L-D-Q-H-D-E-L-G-V-V-E-S-I-K-A-V-S-D-L-Y-A-P-V-S-G-E-V-T-A-V-N-D-A-L-T-N-E-P-E-L-V-N-E-A-P-F-G-D-G-W-L-V-E-I-D-F-D-S-D-D-L-E-A-T-L-D-S-D-D-Y-R-A-Q-I-A"} +{"text": "### FUNCTION Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7 ### SEQUENCE -M-A-Q-T-Q-L-P-H-D-A-K-A-G-P-T-K-P-E-V-R-A-V-V-R-S-K-L-A-L-T-D-D-D-H-F-V-E-V-G-S-C-T-G-A-V-T-I-A-A-A-R-D-A-G-R-V-T-A-L-E-R-K-A-D-R-L-E-T-T-R-K-N-L-A-A-N-G-L-A-D-A-V-E-L-R-N-A-E-A-P-A-E-L-P-A-D-A-D-A-L-F-I-G-G-S-R-N-Y-D-A-V-L-D-H-A-A-E-T-G-V-D-R-I-V-M-N-V-S-R-L-E-V-A-G-A-A-T-Q-A-F-R-D-R-D-I-L-T-E-V-V-Q-F-Q-V-S-H-G-Y-E-L-A-G-A-T-S-F-D-S-E-N-P-V-Y-M-L-V-G-S-A-S-G-D-T-E-A-D-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-G-A-G-T-P-S-Q-G-K-K-N-T-T-T-H-T-K-C-R-R-C-G-E-K-S-Y-H-T-K-K-K-V-C-S-S-C-G-F-G-A-S-A-K-R-R-D-Y-E-W-Q-G-K-T-G-D-N"} +{"text": "### FUNCTION Activates transcription of bacteriorhodopsin ### SEQUENCE -M-P-I-T-D-L-H-C-P-R-C-G-S-D-V-K-M-G-L-P-M-G-A-T-V-K-S-V-T-A-A-S-R-Q-E-P-T-S-D-T-Q-K-V-R-T-V-E-C-R-N-D-H-E-F-F-V-R-F-E-W"} +{"text": "### FUNCTION Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP ### SEQUENCE -M-V-E-N-V-I-W-P-A-Y-F-D-A-A-L-S-R-R-D-G-R-R-V-P-M-E-L-A-V-E-E-P-S-I-D-E-I-A-T-A-V-Q-Q-V-G-Y-D-A-V-V-E-R-D-V-A-Y-P-R-R-H-W-D-A-A-G-R-V-L-V-K-D-A-D-D-A-K-N-T-L-V-Q-A-V-A-A-Y-V-G-A-L-R-D"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-K-H-L-P-K-H-V-R-P-R-W-R-Y-L-A-V-G-I-E-A-W-P-D-A-G-I-E-R-S-D-F-Q-R-A-L-W-F-A-A-G-N-L-L-G-D-P-G-S-A-D-A-G-V-R-V-V-A-Y-S-F-R-D-G-R-G-E-A-L-V-R-A-R-R-G-T-V-S-R-A-R-A-A-V-A-C-V-S-A-V-R-E-H-P-V-R-V-C-V-R-G-V-S-G-T-M-R-A-A-R-E-R-Y-L-D-G-L-D-T-P-E-R-R-S-D-V-A-F-D-G-D-A-R-D-G-V-C-R-G-E-N-V-D-V-V-A-G-D-D-G-W-V-G-A-R-R-R-D-C-G-T-D-G-E"} +{"text": "### FUNCTION eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA ### SEQUENCE -M-D-Y-E-E-Q-L-D-R-A-M-D-E-K-P-D-V-T-G-S-E-T-R-F-E-V-P-D-P-N-V-R-K-E-G-N-V-T-V-Y-E-N-F-Q-A-T-L-D-A-L-S-R-T-Q-D-H-V-L-K-F-L-Q-N-E-V-G-T-S-A-S-I-D-E-S-G-R-A-R-L-T-G-E-F-G-Q-R-R-V-S-D-T-L-D-A-Y-V-E-T-Y-V-T-C-P-E-C-G-L-P-D-T-N-L-E-T-D-G-D-T-I-Q-L-H-C-E-A-C-G-A-R-S-T-V"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-G-T-E-T-A-T-L-G-G-G-C-F-W-C-T-E-A-A-M-E-E-L-A-G-V-T-D-V-T-S-G-Y-A-G-G-D-T-A-D-P-S-Y-R-D-V-C-S-G-T-T-G-H-A-E-V-V-Q-V-E-Y-D-T-A-E-L-A-Y-E-D-V-L-E-V-F-F-T-V-H-D-P-T-T-V-D-R-E-G-P-D-V-G-S-Q-Y-R-S-I-V-L-P-H-D-D-Q-Q-H-E-R-A-T-A-F-V-D-E-L-A-A-A-D-A-F-D-G-S-I-V-T-E-I-E-P-L-E-T-F-Y-P-A-A-E-K-H-Q-N-Y-F-E-K-N-P-D-A-A-Y-C-T-V-N-V-A-P-K-V-S-K-V-R-E-Q-F-G-A-R-T-E"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-S-K-V-A-A-V-L-K-V-M-P-D-S-P-D-I-D-L-D-G-L-E-A-D-L-S-E-S-L-P-D-G-A-E-I-N-G-T-D-T-E-E-V-A-F-G-L-T-A-L-L-T-T-V-I-V-P-D-D-S-G-G-T-E-A-V-E-D-A-F-G-A-V-D-D-V-E-S-V-S-V-E-E-V-G-R-L"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-S-L-A-E-F-D-A-D-V-V-V-D-A-R-D-C-I-M-G-R-V-A-S-N-V-A-E-R-A-L-A-G-D-R-V-A-V-V-N-A-E-Q-A-V-I-T-G-T-E-D-D-V-F-S-T-Y-R-T-R-A-N-L-G-S-D-R-G-P-Y-Y-P-K-R-P-D-G-I-F-K-R-A-I-R-G-M-L-P-Y-K-Q-D-D-G-R-E-A-L-D-S-V-R-V-Y-V-G-N-P-M-D-E-D-G-D-V-L-D-G-T-S-L-D-R-L-S-T-I-R-F-V-T-L-S-E-V-S-E-E-L-G-A-N-V-T-W"} +{"text": "### FUNCTION Located on the platform of the 30S subunit ### SEQUENCE -M-A-D-D-T-K-W-G-I-A-H-V-H-A-S-F-N-N-T-I-M-T-V-T-D-Q-T-G-A-E-T-L-A-K-S-S-G-G-S-V-V-K-Q-N-R-D-E-A-S-P-Y-A-A-M-Q-M-A-E-Q-L-A-E-E-V-L-D-Q-G-I-E-K-V-H-V-R-V-R-G-P-G-G-N-L-Q-R-S-P-G-P-G-A-Q-A-A-I-R-A-L-A-R-A-G-L-E-I-G-R-I-E-D-V-T-P-I-P-H-D-G-T-R-P-P-K-N-S-G-Y"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-L-P-G-E-N-T-K-F-Y-E-T-P-N-H-P-Y-Q-G-E-R-I-A-E-E-S-D-L-L-S-R-Y-G-L-K-N-K-E-E-L-W-R-A-Q-S-E-L-R-D-Y-R-R-E-A-R-R-L-L-G-Q-T-G-T-V-S-G-E-E-F-V-A-R-L-Q-R-I-G-I-L-S-E-E-E-R-L-D-D-V-L-S-L-E-V-T-D-V-L-E-R-R-L-Q-T-V-V-Y-R-E-G-L-A-N-T-M-G-Q-A-R-Q-F-V-S-H-G-H-V-T-V-D-G-S-R-V-T-E-P-S-Y-T-V-P-V-S-E-E-N-T-L-A-F-D-E-T-S-D-L-T-D-E-L-H-P-A-R-A-G-A-Q-E"} +{"text": "### FUNCTION Broad-specificity nucleoside monophosphate kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-R-V-A-V-T-G-T-P-G-T-G-K-T-T-A-T-G-R-L-D-T-A-L-D-V-A-H-L-N-D-L-V-G-T-E-G-L-Y-D-G-V-D-A-D-R-G-S-K-I-V-D-V-D-A-V-R-D-H-F-A-G-R-E-D-V-L-V-E-S-H-L-A-H-R-L-D-D-L-D-A-V-V-V-L-R-C-A-P-E-T-L-A-T-R-L-Q-D-R-G-D-S-P-E-K-A-A-E-N-A-D-S-E-A-L-A-I-I-L-S-E-A-V-R-G-H-G-A-D-A-V-Y-E-I-D-T-T-D-R-S-P-D-A-V-A-A-A-I-Q-A-V-L-D-G-D-R-E-P-S-A-G-T-V-D-Y-T-D-Y-V"} +{"text": "### FUNCTION May be involved in the biogenesis/assembly of dimethyl sulfoxide reductase ### SEQUENCE -M-T-P-A-T-R-N-N-D-S-A-V-A-V-A-D-A-F-D-D-T-G-D-G-P-P-T-A-A-R-F-A-A-L-A-A-C-W-R-Q-P-D-D-D-L-Q-A-A-L-A-A-E-T-D-T-T-V-D-A-Q-S-L-R-A-E-Y-T-R-L-F-V-G-P-G-P-S-Q-S-P-P-Y-E-S-V-Y-R-D-G-E-R-D-A-D-L-G-P-V-Y-G-S-S-T-Q-A-V-A-R-W-Y-S-E-Y-G-L-Q-P-A-A-S-E-S-A-P-P-D-H-L-A-T-E-L-E-F-A-A-Y-L-R-E-H-E-G-A-E-T-L-E-Q-F-L-T-E-H-P-R-N-W-V-E-S-F-A-R-R-V-R-D-A-D-P-K-P-F-Y-R-T-L-L-N-V-T-V-D-T-L-A-R-A-D-T-P-L"} +{"text": "### FUNCTION Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein and RNA polymerase recruitment Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes ### SEQUENCE -M-A-F-E-D-L-L-D-D-P-V-V-Q-K-Y-L-H-E-L-V-G-P-K-G-M-P-V-A-A-A-P-P-D-G-E-V-T-D-E-E-L-A-E-R-L-G-L-E-L-N-D-V-R-R-A-L-F-I-L-Y-E-N-D-L-A-T-Y-R-R-V-R-D-E-D-S-G-W-L-T-Y-L-W-T-F-Q-Y-E-N-V-P-G-N-L-R-E-E-M-D-R-L-L-E-A-L-V-D-R-R-E-Y-E-L-E-N-E-F-Y-L-C-E-V-C-S-I-R-F-E-F-G-E-A-M-D-L-G-F-E-C-P-E-C-G-S-A-V-E-A-M-E-N-T-D-L-V-D-A-M-D-D-R-I-E-R-L-R-S-E-L-A-V-E-A"} +{"text": "### FUNCTION Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs ### SEQUENCE -M-Q-S-H-P-E-V-A-V-L-R-Y-G-H-R-P-G-R-D-D-R-M-T-T-H-V-G-L-T-A-R-A-L-G-A-D-R-V-L-F-P-D-N-A-T-Q-A-A-E-T-V-R-D-I-T-G-R-F-G-G-P-F-D-V-E-R-T-T-E-L-N-A-T-I-E-D-W-P-G-V-V-V-H-L-T-M-Y-G-E-Q-L-Q-S-V-D-D-E-I-R-T-T-H-R-E-E-P-V-L-V-V-V-G-G-E-K-V-P-G-D-V-Y-E-A-A-D-W-N-V-G-V-T-N-Q-P-H-S-E-V-A-G-L-A-V-F-L-D-R-L-F-D-G-R-E-L-E-Q-G-Y-E-N-A-E-R-R-V-I-P-E-E-L-G-K-H-V-V-D-V-E-D-G-D-H-A-E-G-A-A-A-G-D-G-D"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-R-L-G-L-V-V-A-E-F-N-R-S-V-T-E-R-M-E-A-A-A-R-E-A-A-A-D-A-D-A-A-I-T-D-T-V-H-V-P-G-A-Y-D-S-P-L-A-A-D-R-L-A-R-R-D-D-I-D-A-V-A-V-V-G-A-I-V-T-G-D-T-D-H-D-H-V-I-A-S-A-T-A-D-T-L-T-D-V-S-L-E-R-D-T-P-V-T-F-G-V-S-G-P-G-M-S-G-A-E-A-R-E-R-V-E-K-G-A-A-A-V-E-S-A-V-S-L-T-Q-E-L"} +{"text": "### FUNCTION May catalyze a purine salvage reaction, the substrate is unknown ### SEQUENCE -M-D-R-L-K-Q-S-L-L-D-A-P-I-I-E-K-D-G-Y-H-Y-F-V-H-P-I-S-D-G-V-P-M-L-E-P-E-L-L-R-E-I-V-I-R-I-I-R-K-A-E-L-D-E-V-D-K-I-V-T-P-A-A-M-G-I-H-I-S-T-A-V-S-L-M-T-D-I-P-I-V-V-I-R-K-R-E-Y-G-L-P-G-E-V-A-L-S-Q-E-T-G-Y-S-E-N-E-M-Y-I-N-D-V-H-E-G-D-R-V-L-V-L-D-D-V-L-S-T-G-G-T-L-R-A-I-T-D-A-L-E-Q-T-G-A-D-V-A-D-V-L-A-V-I-K-K-A-G-P-N-E-L-D-D-T-D-M-D-V-R-T-L-I-N-V-D-V-A-D-G-E-V-V-V-V-D-D-Q-G-D-H"} +{"text": "### FUNCTION Involved in ribosome biogenesis ### SEQUENCE -M-K-S-D-I-R-V-C-E-A-W-R-S-H-H-D-G-P-V-Y-T-L-S-E-T-C-P-E-C-G-G-D-A-V-N-S-A-P-A-P-F-D-P-A-D-P-H-G-K-Y-R-R-A-L-K-E-R-R-R-L"} +{"text": "### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-F-G-G-G-G-M-N-P-R-K-M-Q-Q-M-M-E-Q-M-G-I-D-V-D-E-L-D-A-T-E-V-V-I-S-L-D-D-G-T-E-V-V-F-S-D-P-D-V-T-K-M-D-A-R-G-Q-E-T-Y-Q-V-L-G-D-P-V-E-R-D-A-A-D-A-I-E-A-A-P-A-D-D-S-D-D-T-D-D-D-D-A-I-P-Q-G-D-V-D-I-V-V-Q-R-A-S-V-P-E-D-E-A-R-E-A-L-E-A-A-D-G-D-L-A-A-A-I-D-H-V-D-E"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-D-V-P-L-E-L-S-A-Y-T-R-V-L-R-L-A-S-T-P-S-W-E-E-F-S-Q-I-A-K-I-A-G-A-G-I-L-L-I-G-A-I-G-F-L-V-F-L-I-M-G-G-I-V-S-V-I"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-Q-G-N-L-P-P-E-A-Q-E-K-L-E-Q-L-Q-D-L-Q-E-K-A-Q-N-V-A-T-Q-K-Q-Q-A-E-Q-Q-L-S-E-A-E-T-A-L-D-A-L-G-D-I-E-E-S-T-T-M-Y-R-E-V-G-E-L-L-V-E-T-E-Y-D-N-A-H-D-D-L-D-E-K-V-S-D-L-E-V-R-V-E-T-L-Q-K-Q-E-D-R-V-Q-E-Q-F-E-S-L-Q-E-E-L-Q-D-M-L-G-G-A-G-G-A-M-G-G-G-P-G-A"} +{"text": "### FUNCTION Catalyzes the synthesis of GMP from XMP ### SEQUENCE -M-T-H-I-L-V-V-D-N-H-G-Q-F-T-H-L-E-H-R-L-L-R-D-M-D-G-V-T-V-D-L-T-D-N-T-T-P-P-A-D-I-D-A-D-G-L-V-L-S-G-G-P-T-M-A-D-I-G-H-C-R-E-Y-L-T-L-D-V-P-I-L-G-V-C-L-G-H-Q-L-I-A-D-E-L-G-G-R-I-E-A-G-D-Y-G-G-Y-A-D-V-T-V-S-I-S-D-A-D-D-P-L-V-G-S-L-A-P-D-T-R-V-W-A-S-H-A-D-E-V-V-A-V-P-D-G-F-T-I-T-A-E-S-D-I-C-G-V-E-A-M-G-D-T-D-R-D-L-Y-G-V-Q-W-H-P-E-V-A-H-T-E-E-G-E-A-V-F-E-N-F-V-A-I-C-E"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-S-V-V-S-V-S-M-P-E-E-L-L-E-R-L-D-D-F-A-D-D-H-G-Y-T-G-R-S-E-V-V-R-E-A-S-R-N-L-L-G-E-F-E-D-K-K-L-E-G-R-E-L-M-G-V-V-T-V-V-F-D-Y-E-T-T-T-V-E-E-K-M-M-H-L-R-H-E-H-E-G-L-V-A-S-N-F-H-S-H-V-G-G-H-H-C-M-E-L-F-V-L-E-G-S-L-E-S-I-S-T-F-V-G-K-I-R-A-T-K-D-T-L-T-I-D-Y-S-V-L-P-V-D-E-F-G-G-L-A-D-V-S"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-V-S-R-D-F-D-R-D-K-R-L-L-T-A-R-Q-F-S-A-V-F-D-S-P-T-G-K-V-P-G-K-H-V-L-L-L-A-R-E-N-G-L-D-H-P-R-L-G-L-V-I-G-K-K-N-V-K-L-A-V-Q-R-N-R-L-K-R-L-I-R-E-S-F-R-H-N-Q-E-T-L-A-G-W-D-I-V-V-I-A-R-K-G-L-G-E-L-E-N-P-E-L-H-Q-Q-F-G-K-L-W-K-R-L-L-R-N-R-P-R-T-E-S-P-A-D-A-P-G-V-A-D-G-T-H-A"} +{"text": "### FUNCTION A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex ### SEQUENCE -M-P-S-R-L-P-A-F-R-L-L-L-V-Q-L-V-V-V-L-V-A-A-I-S-L-W-I-S-W-G-P-V-A-G-Y-S-G-L-L-G-G-M-I-A-W-L-P-N-C-Y-F-A-Y-K-A-F-R-F-S-G-A-R-A-A-R-E-I-V-R-S-F-Y-A-G-E-A-G-K-L-I-L-T-A-V-L-F-A-L-A-F-A-G-V-K-P-L-M-A-P-A-L-F-G-V-Y-L-L-T-L-M-V-S-W-C-A-P-L-L-M-G-K-T-F-T-R-P"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-I-N-A-T-L-I-G-Q-S-V-A-F-F-I-F-V-L-F-C-M-K-F-V-W-P-P-V-I-A-A-L-Q-E-R-Q-K-K-I-A-D-G-L-D-A-A-N-R-A-A-R-D-L-E-L-A-H-E-K-A-G-Q-Q-L-R-E-A-K-A-Q-A-A-E-I-V-E-Q-A-K-K-R-A-N-Q-I-V-D-E-A-R-D-Q-A-R-T-E-G-E-R-L-K-A-Q-A-Q-A-E-I-E-Q-E-L-N-S-V-K-D-A-L-R-A-Q-V-G-A-L-A-V-T-G-A-E-K-I-L-G-A-S-I-D-A-N-A-H-E-Q-L-V-S-K-L-A-A-E-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-L-T-T-L-A-R-P-Y-A-K-A-A-F-E-Y-A-Q-A-H-Q-Q-L-A-D-W-S-A-A-L-G-V-L-A-A-V-S-Q-D-D-T-V-R-Q-L-L-K-E-P-Q-L-T-S-S-A-K-A-Q-S-L-I-D-V-C-G-D-K-L-N-A-P-A-Q-N-F-V-R-T-V-A-E-N-K-R-L-E-L-L-P-T-I-A-E-M-Y-E-Q-L-K-A-E-Q-E-K-S-V-E-V-E-V-T-S-A-F-T-L-S-K-E-Q-Q-D-K-L-A-K-A-L-S-A-R-L-S-R-E-V-R-L-H-A-S-E-D-A-S-L-I-G-G-V-I-I-R-A-G-D-L-V-I-D-G-S-V-R-G-K-L-A-K-L-A-E-A-L-K-S"} +{"text": "### FUNCTION Catalyzes the transfer of an acetyl group from acetyl coenzyme A to an acceptor substrate and releases both CoA and the acetylated product It prefers the antibiotic chloramphenicol ### SEQUENCE -M-S-N-V-Q-N-A-S-R-S-S-A-F-A-A-V-E-G-D-H-W-V-E-S-L-D-D-G-R-H-V-L-I-R-P-L-R-E-E-D-R-E-R-E-R-Q-F-I-N-R-L-S-P-A-T-R-H-F-R-F-L-G-E-I-K-E-A-S-P-A-L-L-D-Q-L-M-D-I-D-Y-Q-Q-S-M-A-F-V-A-L-V-H-E-D-G-E-L-R-E-V-G-I-S-R-Y-A-A-C-C-E-E-G-Q-C-E-C-A-V-T-I-A-D-D-Y-Q-G-L-G-L-D-A-V-L-M-R-H-L-I-D-V-A-R-R-N-G-F-R-Q-M-Y-S-V-D-S-A-A-N-R-A-M-R-D-L-C-C-A-L-G-F-V-G-Q-R-D-P-D-D-S-T-Q-V-I-H-R-L-A-L"} +{"text": "### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-V-G-M-Q-P-I-R-R-S-Q-L-I-H-A-T-L-E-A-V-D-Q-V-G-M-G-D-A-S-I-A-L-I-A-R-L-A-G-V-S-N-G-I-I-S-H-Y-F-Q-D-K-N-G-L-L-E-A-T-M-R-H-L-L-S-A-L-S-K-A-V-R-E-R-R-A-A-L-Y-D-D-S-P-R-A-H-L-R-A-I-V-E-G-N-F-D-D-S-Q-V-N-G-P-A-M-K-T-W-L-A-F-W-A-T-S-M-H-Q-P-A-L-R-R-L-Q-R-V-N-D-H-R-L-Y-S-N-L-C-Y-Q-F-R-R-Q-L-S-A-D-D-A-R-A-A-A-R-G-L-A-A-L-I-D-G-L-W-L-R-G-A-L-T-G-D-A-F-D-T-D-E-A-L-N-I-A-Y-D-Y-L-D-Q-Q-L-A-K-Q-S-G"} +{"text": "### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate for the ubiquinone pathway ### SEQUENCE -M-P-S-N-A-L-W-L-R-A-D-Q-L-S-S-V-S-P-A-V-L-D-W-L-F-D-E-G-S-L-T-R-R-L-T-A-L-A-D-G-A-F-R-V-E-P-L-L-E-G-W-Q-T-L-R-D-D-E-C-Q-G-L-D-V-P-T-G-S-S-G-W-V-R-E-V-Y-L-H-G-H-D-R-P-W-V-F-A-R-S-V-A-A-R-S-A-L-E-G-S-G-F-D-L-A-L-L-G-T-R-S-L-G-E-L-L-F-S-D-S-A-F-E-R-G-P-I-E-V-C-R-Y-P-A-A-G-L-P-A-E-V-R-A-E-G-L-W-G-R-R-S-R-F-S-R-G-A-L-G-V-L-V-A-E-V-Y-L-P-R-L-W-D-Q-A-G-I-A-D-V"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-R-K-P-E-L-A-A-A-I-A-E-K-A-D-L-T-K-E-Q-A-N-R-V-L-N-A-L-L-D-E-I-T-G-A-L-N-R-K-D-S-V-T-L-V-G-F-G-T-F-L-Q-R-H-R-G-A-R-T-G-K-N-P-Q-T-G-Q-P-V-K-I-K-A-S-N-T-V-A-F-K-P-G-K-A-L-R-D-A-V-N"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-C-L-D-N-V-D-N-R-F-E-L-V-M-L-A-T-K-R-A-R-Q-L-A-T-G-G-K-E-P-K-V-A-W-E-N-D-K-P-T-V-V-A-L-R-E-I-A-S-G-L-V-D-E-N-V-V-Q-Q-E-D-I-V-E-D-E-P-L-F-A-A-F-D-D-E-A-N-T-E-A-L"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-E-A-R-F-H-D-L-V-D-A-L-Q-Q-Q-V-E-D-A-F-D-D-S-D-L-D-L-D-L-E-N-A-G-G-V-L-T-V-R-F-E-N-G-S-Q-L-I-L-S-R-Q-A-P-L-R-Q-L-W-V-A-A-K-S-G-G-F-H-F-D-Y-D-E-A-S-G-L-W-R-H-D-G-S-Q-E-P-L-G-A-L-L-N-R-A-T-L-E-Q-G-G-E-D-V-E-F-P-G-L"} +{"text": "### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-S-Q-S-N-T-L-T-V-Q-I-L-D-K-E-Y-C-I-N-C-P-D-D-E-R-A-N-L-E-S-A-A-R-Y-L-D-G-K-M-R-E-I-R-S-S-G-K-V-I-G-A-D-R-V-A-V-M-A-A-L-N-I-T-H-D-L-L-H-R-K-E-R-L-D-Q-E-S-S-S-T-R-E-R-V-R-E-L-L-D-R-V-D-R-A-L-A-N-P-A-D-A-G-E-A"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-I-P-A-E-L-R-Y-A-Q-S-H-E-W-A-R-L-E-A-D-G-S-V-T-V-G-I-S-D-H-A-Q-E-A-L-G-D-V-V-F-I-E-L-P-E-L-G-K-T-L-A-A-G-Q-E-A-G-V-V-E-S-V-K-A-A-S-D-I-Y-S-P-I-G-G-E-V-I-A-I-N-E-A-L-A-D-T-P-E-D-V-N-N-D-P-Y-V-S-W-F-F-K-L-K-P-S-N-P-A-E-L-D-K-L-L-D-A-A-G-Y-Q-A-A-V-D-A-E-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-M-C-R-K-Y-H-E-E-L-P-G-L-D-R-P-P-Y-P-G-A-K-G-E-D-I-Y-N-N-V-S-R-K-A-W-D-E-W-Q-K-H-Q-T-M-L-I-N-E-R-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-Q-E-M-D-K-F-L-S-G-E-D-Y-A-K-A-D-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-P-P-V-V-I-Y-T-T-A-W-C-P-Y-C-I-R-A-K-Q-L-L-Q-R-K-G-V-D-F-Q-E-I-A-C-D-G-K-P-E-L-R-A-E-L-A-R-K-A-G-S-T-T-V-P-Q-I-W-I-G-E-T-H-V-G-G-C-D-D-L-H-A-L-E-R-A-G-K-L-D-A-L-L-S-A"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-T-E-Q-A-T-N-G-A-A-D-E-Q-Q-P-Q-F-S-L-Q-R-I-Y-L-R-D-L-S-F-E-S-P-K-S-P-E-I-F-R-Q-E-W-N-P-S-I-S-L-D-L-N-T-R-Q-K-Q-L-D-G-D-F-Y-E-V-V-L-T-V-S-V-T-V-K-N-G-E-D-T-T-A-F-I-A-E-V-Q-Q-A-G-I-F-L-I-K-N-L-D-P-S-S-M-S-H-T-L-G-A-F-C-P-N-I-L-F-P-Y-A-R-E-A-L-D-N-L-V-V-R-G-S-F-P-A-L-M-L-S-P-V-N-F-D-A-L-Y-A-Q-E-I-A-R-M-Q-A-S-G-E-I-P-T-P-S-V-Q"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-I-F-D-W-K-H-W-I-V-I-L-I-V-V-V-L-V-F-G-T-K-R-L-K-N-L-G-S-D-V-G-E-A-I-K-G-F-R-K-A-V-N-T-E-E-D-D-K-K-D-Q-P-A-A-Q-P-A-Q-P-L-N-Q-P-H-T-I-D-A-Q-A-Q-K-V-E-E-P-A-R-K-D"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-D-I-H-P-T-Y-E-A-I-E-A-T-C-S-C-G-N-V-I-K-T-R-S-T-L-C-K-P-I-H-L-D-V-C-S-E-C-H-P-F-Y-T-G-K-Q-K-V-L-D-T-G-G-R-I-D-R-F-K-Q-R-F-G-V-F-G-A-T-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-L-V-H-P-D-Q-S-E-Q-V-G-G-M-V-E-R-Y-T-K-A-I-E-E-D-G-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-A-I-N-N-V-H-K-A-H-Y-V-L-M-N-V-E-C-S-A-K-A-L-A-E-L-E-D-N-F-R-Y-N-D-A-V-I-R-N-L-V-M-R-R-D-E-A-V-T-E-Q-S-E-M-L-K-A-E-E-S-R-N-E-R-R-E-R-R-E-R-P-N-D-N-A-E-G-A-D-G-D-D-N-S-D-S-D-N-A-D-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-F-F-R-R-R-K-F-C-R-F-T-A-E-G-V-K-E-I-D-Y-K-D-L-N-T-L-K-A-Y-V-S-E-T-G-K-I-V-P-S-R-I-T-G-T-K-A-K-Y-Q-R-Q-L-A-T-A-I-K-R-A-R-Y-L-A-L-L-P-Y-T-D-S-H-G-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-V-I-L-L-E-K-V-A-N-L-G-N-L-G-D-K-V-N-I-K-G-G-Y-A-R-N-F-L-L-P-Q-G-K-A-T-V-A-T-A-E-N-V-A-A-F-E-A-R-R-A-E-L-E-K-A-A-A-E-K-K-A-A-A-E-A-R-A-A-Q-L-S-E-L-V-V-T-L-G-A-H-A-G-D-E-G-K-L-F-G-S-I-G-T-R-D-I-A-E-A-V-S-A-A-G-Y-P-L-E-K-A-E-V-R-L-P-N-G-A-L-R-N-T-G-E-F-D-V-A-V-H-L-H-T-D-V-E-T-T-L-K-L-I-I-V-A-E"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-L-V-I-H-Q-R-L-P-A-R-S-P-R-W-D-E-E-L-H-L-T-Y-E-A-R-S-K-S-R-L-R-C-F-A-A-S-G-E-E-V-G-L-F-L-E-R-G-Q-P-P-L-A-D-G-D-C-L-E-A-R-D-G-R-L-V-R-V-V-A-R-S-E-R-L-L-H-V-T-C-A-S-P-L-E-L-T-R-A-A-Y-H-L-G-N-R-H-V-A-L-Q-V-G-D-G-W-L-R-L-L-D-D-Y-V-L-K-A-M-L-E-Q-L-G-A-T-V-E-A-I-E-A-P-F-Q-P-E-H-G-A-Y-G-G-G-H-H-H-S-H-H-G-E-A-E-F-N-Y-A-P-R-L-H-Q-F-G-V-R-R"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-Q-K-K-H-P-S-G-T-I-A-Q-N-K-K-A-L-H-D-Y-F-I-E-Q-R-F-E-A-G-V-A-L-A-G-W-E-V-K-S-L-R-A-G-K-A-Q-L-V-D-S-Y-V-L-L-K-D-G-E-A-W-L-L-G-S-H-I-T-P-L-T-T-A-S-T-H-V-I-A-D-P-V-R-T-R-K-L-L-L-H-K-R-E-L-G-K-L-F-G-A-V-Q-Q-K-G-Y-A-C-V-A-L-S-M-Y-W-K-K-H-L-V-K-C-E-I-A-L-A-K-G-K-K-D-F-D-K-R-H-T-E-K-E-R-D-S-D-R-E-I-Q-R-A-M-R-H-G-K-D-D"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-D-E-Q-Q-T-L-D-Q-Q-T-P-E-Q-P-T-G-A-A-E-D-L-T-A-R-V-Q-E-L-E-E-Q-L-A-A-A-Q-D-Q-A-L-R-M-V-A-D-L-Q-N-V-R-R-R-A-E-Q-D-V-E-K-A-H-K-F-A-L-E-K-F-A-G-D-L-L-A-V-V-D-T-L-E-R-G-L-E-M-S-D-P-N-D-E-A-I-K-P-M-R-E-G-M-E-L-T-L-K-M-F-D-D-T-L-R-R-Y-Q-V-E-A-L-N-P-E-G-E-P-F-N-P-E-Q-H-Q-A-M-A-M-Q-E-S-A-S-A-E-P-G-S-V-L-K-V-F-Q-K-G-Y-L-L-N-G-R-L-L-R-P-A-M-V-V-V-S-K-A-P-A-E-T-P-P-S-I-D-E-Q-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-K-F-P-M-T-V-Q-G-A-R-A-L-E-E-E-V-K-H-L-K-G-V-L-R-P-Q-I-S-Q-A-I-A-E-A-R-E-L-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-Q-Q-G-M-V-E-A-R-I-R-D-I-E-A-K-L-S-N-A-Q-V-I-D-V-T-A-I-P-H-S-G-K-V-I-F-G-T-T-V-D-I-A-N-V-E-T-D-E-T-V-T-Y-Q-I-V-G-D-D-E-A-D-I-K-G-G-K-I-S-V-N-S-P-I-A-R-A-L-I-G-K-T-E-G-D-A-V-L-V-R-T-P-G-G-D-V-E-Y-E-I-V-E-V-R-H-I"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-L-E-K-V-V-I-V-V-H-L-L-M-A-L-G-L-V-G-L-I-L-V-Q-H-G-K-G-A-D-A-G-A-S-F-G-A-G-A-S-A-T-V-F-G-S-Q-G-S-A-T-F-L-S-R-I-T-G-I-L-A-A-V-F-F-L-T-S-L-G-L-A-Y-F-A-K-E-K-S-D-A-L-Q-H-I-G-L-P-D-P-A-V-L-E-Q-K-Q-E-K-A-P-A-A-D-D-V-P-V-L-Q-E-Q-S-K-P-A-E-S-A-G-D-V-P-A-A-P-E-Q-K"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-S-K-L-E-Q-L-Q-A-L-L-A-P-V-V-E-A-L-G-Y-E-C-W-G-V-E-F-I-S-Q-G-R-H-S-V-L-R-V-Y-I-D-R-P-E-G-I-L-I-D-D-C-E-A-V-S-R-Q-V-S-G-I-L-D-V-E-D-P-I-S-G-E-Y-T-L-E-V-S-S-P-G-M-D-R-P-L-F-T-L-E-Q-F-A-K-H-A-G-E-Q-V-K-I-R-L-R-S-P-Y-E-G-R-R-N-Y-Q-G-I-L-R-G-V-E-E-Q-D-V-V-V-L-V-D-D-H-E-Y-L-L-P-I-D-S-I-D-K-A-N-I-I-P-R-F-D"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-D-Y-S-R-T-Q-R-I-G-D-Q-M-Q-R-E-L-A-Q-L-I-Q-R-E-I-K-D-P-R-L-G-L-V-T-I-T-G-V-E-V-S-R-D-V-A-H-A-K-V-F-I-T-V-M-G-Q-D-D-A-G-K-I-A-L-N-M-E-I-L-N-D-A-A-G-Y-L-R-M-L-L-G-K-S-M-K-L-R-S-V-P-Q-L-H-F-H-Y-D-E-S-I-R-R-G-A-E-L-S-A-L-I-E-R-A-V-A-E-D-G-R-R-H-G-D-E-T-E-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-S-V-E-E-K-A-Q-I-V-N-E-Y-K-Q-A-E-G-D-T-G-S-P-E-V-Q-V-A-L-L-S-A-N-I-N-K-L-Q-D-H-F-K-A-N-G-K-D-H-H-S-R-R-G-L-I-R-M-V-N-Q-R-R-K-L-L-D-Y-L-K-G-K-D-V-S-R-Y-T-A-L-I-G-R-L-G-L-R-R"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-A-V-Q-L-I-V-G-L-G-N-P-G-P-E-Y-D-Q-T-R-H-N-A-G-A-L-F-V-E-R-L-A-H-A-Q-G-V-S-L-V-A-D-R-K-Y-F-G-L-V-G-K-F-S-H-Q-G-K-D-V-R-L-L-I-P-T-T-Y-M-N-R-S-G-Q-S-V-A-A-L-A-G-F-F-R-I-A-P-D-A-I-L-V-A-H-D-E-L-D-M-P-P-G-V-A-K-L-K-T-G-G-G-H-G-G-H-N-G-L-R-D-I-I-A-Q-L-G-N-Q-N-S-F-H-R-L-R-L-G-I-G-H-P-G-H-S-S-L-V-S-G-Y-V-L-G-R-A-P-R-S-E-Q-E-L-L-D-T-S-I-D-F-A-L-G-V-L-P-E-M-L-A-G-D-W-T-R-A-M-Q-K-L-H-S-Q-K-A"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-G-L-L-S-E-F-K-A-F-A-V-K-G-N-V-V-D-M-A-V-G-I-I-I-G-A-A-F-G-K-I-V-S-S-F-V-G-D-V-I-M-P-P-I-G-L-L-I-G-G-V-D-F-S-D-L-A-I-T-L-K-A-A-E-G-D-V-P-A-V-V-L-A-Y-G-K-F-I-Q-T-V-L-D-F-V-I-V-A-F-A-I-F-M-G-V-K-A-I-N-R-L-K-R-E-E-A-V-A-P-S-E-P-P-V-P-S-A-E-E-T-L-L-T-E-I-R-D-L-L-K-A-Q-Q-N-K-S"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-V-T-G-G-K-Q-H-K-V-T-E-G-E-F-L-K-V-E-K-L-D-V-A-T-G-E-A-I-D-F-D-R-V-L-L-V-A-N-G-E-D-V-K-I-G-L-P-V-V-E-G-A-K-V-T-A-E-V-V-S-H-G-R-H-D-K-V-R-I-I-K-F-R-R-R-K-H-H-M-K-R-Q-G-H-R-Q-W-F-T-E-I-K-I-T-G-I-Q-A"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-S-Q-P-L-T-V-E-C-P-T-C-G-A-P-V-E-W-K-S-D-N-K-Y-R-P-F-C-S-D-R-C-K-L-I-D-L-G-A-W-A-A-E-E-H-A-I-P-G-D-T-L-E-D-D-I-F-S-A-D-L-P-P-R-E-H"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-P-A-L-E-I-T-I-I-N-K-L-G-L-H-A-R-A-A-A-K-F-V-G-V-A-G-R-Y-P-C-Q-V-R-V-G-R-N-P-E-S-C-V-D-G-K-S-I-M-A-V-M-M-L-A-A-G-K-G-T-N-L-H-L-H-T-E-G-E-Q-E-D-E-A-L-N-A-L-V-E-L-I-N-N-R-F-D-E-G-E"} +{"text": "### FUNCTION Seems to have a role in regulating nitrogen assimilation ### SEQUENCE -M-I-R-L-E-Q-I-L-T-P-G-R-S-L-V-N-V-P-G-G-S-K-K-R-V-L-E-Q-I-A-N-L-V-A-R-E-L-P-E-F-D-A-Q-T-I-F-E-N-L-V-A-R-E-K-L-G-S-T-G-F-G-N-G-I-A-I-P-H-C-R-L-S-G-C-Q-S-P-I-S-A-V-L-H-L-D-A-P-V-D-F-D-A-L-D-G-A-P-V-D-L-L-F-V-L-L-V-P-E-A-A-T-E-E-H-L-E-L-L-R-Q-I-A-A-M-L-D-R-A-D-V-R-D-R-L-R-S-A-P-T-A-E-A-L-Y-Q-I-V-V-D-V-Q-N-G-Q"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-Y-T-A-K-P-E-T-V-Q-R-D-W-F-V-V-D-A-A-G-Q-T-L-G-R-L-A-T-E-I-A-R-R-L-R-G-K-H-K-P-E-Y-T-P-H-V-D-T-G-D-Y-I-V-V-I-N-A-E-Q-V-R-V-T-G-A-K-T-T-D-K-M-Y-Y-H-H-S-G-F-P-G-G-I-K-S-I-N-F-E-K-L-I-A-K-A-P-E-R-V-I-E-T-A-V-K-G-M-L-P-K-N-P-L-G-R-D-M-Y-R-K-L-K-V-Y-K-G-A-S-H-P-H-T-A-Q-Q-P-Q-E-L-K-I"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-S-R-L-F-V-K-R-L-P-T-G-S-F-L-M-L-L-L-Y-I-G-L-L-L-S-A-I-A-V-A-Y-S-T-Y-W-N-R-Q-L-L-N-S-L-Y-S-E-L-S-V-R-D-K-A-Q-A-E-W-G-R-L-I-L-E-Q-S-T-W-T-A-H-S-R-I-E-S-L-A-V-E-Q-L-R-M-R-V-P-D-P-A-E-V-R-M-V-A-P"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-W-K-S-I-L-A-I-A-L-G-A-A-L-G-A-L-L-R-W-F-L-G-L-K-L-N-S-L-L-P-S-I-P-P-G-T-L-L-A-N-L-V-G-G-Y-V-I-G-A-A-I-A-Y-F-A-Q-A-P-G-I-A-P-E-W-R-L-L-I-I-T-G-F-C-G-G-L-T-T-F-S-T-F-S-A-E-V-V-S-L-L-Q-E-G-R-L-G-W-A-A-G-A-I-A-T-H-V-S-G-S-L-L-M-T-L-L-G-L-F-S-M-N-W-M-L-G-K"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-N-A-K-A-E-A-K-E-S-R-F-D-L-L-K-W-L-L-V-A-V-L-V-V-V-A-V-V-G-N-Q-Y-F-S-A-Q-P-I-L-Y-R-V-L-G-I-L-V-L-A-V-I-A-A-F-L-A-L-Q-T-A-K-G-Q-A-F-F-S-L-A-K-E-A-R-V-E-I-R-K-V-V-W-P-S-R-Q-E-T-T-Q-T-T-L-I-V-V-A-V-V-L-V-M-A-L-L-L-W-G-L-D-S-L-L-G-W-L-V-S-M-I-V-G"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-A-K-R-W-Y-V-V-H-A-Y-S-G-Y-E-K-H-V-M-R-S-L-I-E-R-V-K-L-A-G-M-E-E-E-F-G-E-I-L-V-P-T-E-E-V-V-E-M-R-N-G-Q-K-R-K-S-E-R-K-F-F-P-G-Y-V-L-V-Q-M-E-M-N-E-G-T-W-H-L-V-K-D-T-P-R-V-M-G-F-I-G-G-T-A-D-K-P-A-P-I-T-D-R-E-A-D-A-I-L-R-R-V-A-D-S-G-D-K-P-K-P-K-T-L-F-E-P-G-E-T-V-R-V-I-D-G-P-F-A-D-F-N-G-V-V-E-E-V-N-Y-E-K-S-R-I-Q-V-A-V-L-I-F-G-R-S-T-P-V-E-L-E-F-S-Q-V-E-K-V"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-Q-A-Y-I-K-L-Q-V-K-A-G-Q-A-N-P-S-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-F-N-A-K-T-Q-G-Q-E-P-G-L-P-T-P-V-I-I-T-V-Y-S-D-R-S-F-T-F-E-T-K-S-T-P-A-A-V-L-L-K-K-A-A-G-I-T-S-G-S-A-R-P-N-S-Q-K-V-G-T-V-T-R-A-Q-L-E-E-I-A-K-T-K-Q-A-D-L-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-N-V-E-G-V"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-I-K-L-E-D-K-K-A-I-V-A-E-V-N-E-A-A-K-A-A-L-S-A-V-V-A-D-A-R-G-V-T-V-G-A-M-T-G-L-R-K-E-A-R-E-A-G-V-Y-V-K-V-V-R-N-T-L-L-K-R-A-V-E-G-T-Q-F-D-V-L-N-D-V-F-K-G-P-T-L-I-A-F-S-N-E-H-P-G-A-A-A-R-I-F-R-E-F-A-K-G-Q-D-K-F-E-I-K-A-A-A-F-E-G-Q-F-L-A-A-N-Q-I-D-V-L-A-S-L-P-T-Y-D-E-A-V-S-Q-L-M-S-V-I-Q-G-A-T-S-K-L-A-R-T-L-A-A-I-R-D-Q-K-E-A-A-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-T-N-E-D-I-I-N-A-V-S-E-M-S-V-M-Q-V-V-E-L-I-K-A-M-E-E-K-F-G-V-T-A-A-A-A-T-V-A-A-A-G-P-A-A-A-A-A-E-E-Q-T-E-F-T-I-V-L-A-E-A-G-D-K-K-V-N-V-I-K-V-V-R-E-L-T-G-L-G-L-K-E-A-K-A-V-V-D-G-A-P-G-V-V-K-E-G-A-S-K-E-E-A-E-A-A-K-K-A-L-E-E-A-G-A-K-V-E-L-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-A-A-K-R-E-V-L-A-D-P-K-Y-G-S-Q-I-L-A-K-F-M-N-H-V-M-E-S-G-K-K-A-V-A-E-R-I-V-Y-G-A-L-D-K-V-K-E-R-G-K-A-D-P-L-E-T-F-E-K-A-L-D-A-I-A-P-L-V-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-P-S-R-R-N-A-L-A-M-R-W-L-V-D-F-A-R-K-R-G-E-K-S-M-A-L-R-L-A-G-E-L-L-D-A-A-E-G-K-G-A-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-S-H-Y-R-F"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-Q-I-R-I-R-L-K-A-F-D-H-R-L-I-D-Q-S-T-Q-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-R-F-T-V-L-I-S-P-H-V-N-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-V-L-D-I-V-Q-P-T-D-K-T-V-D-A-L-M-K-L-D-L-A-A-G-V-E-V-Q-I-S-L-G"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-Q-E-R-V-F-K-V-L-L-G-P-H-I-S-E-K-A-T-G-L-A-D-G-K-S-Q-F-V-F-K-V-A-T-D-A-T-K-L-E-I-K-K-A-V-E-S-L-F-S-V-K-V-Q-R-V-T-T-L-N-V-K-G-K-T-K-R-T-A-R-G-L-G-K-R-N-D-W-K-K-A-Y-I-A-L-Q-P-G-Q-D-L-D-F-A-T-S-A-E"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-V-E-V-A-V-E-K-N-D-R-K-P-I-K-T-W-S-R-R-S-M-I-L-P-H-M-V-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-L-V-N-E-D-M-V-G-H-K-L-G-E-F-A-A-T-R-T-Y-R-G-H-A-A-D-K-K-A-K-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-V-A-A-K-L-S-G-A-R-I-S-A-Q-K-A-R-L-V-A-D-Q-I-R-G-K-K-V-G-E-A-L-N-L-L-A-F-S-S-K-K-A-A-E-I-M-K-K-V-L-E-S-A-V-A-N-A-E-H-N-E-G-A-D-V-D-D-L-K-V-S-T-V-F-V-N-E-G-R-S-L-K-R-I-M-P-R-A-K-G-R-A-D-R-I-V-K-R-S-C-H-I-T-V-K-V-A-D-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-Q-M-T-G-H-N-R-G-L-A-H-R-G-S-K-V-S-F-G-E-Y-A-L-K-A-T-S-R-G-R-L-T-A-R-Q-I-E-S-A-R-R-A-L-T-R-H-V-K-R-G-G-K-I-W-I-R-V-F-P-D-K-P-V-T-K-K-P-L-E-V-R-M-G-K-G-K-G-G-V-E-Y-W-V-A-Q-I-Q-P-G-K-V-L-Y-E-I-E-G-V-S-E-E-L-A-R-E-A-F-A-L-A-A-A-K-L-P-L-A-T-S-F-V-K-R-T-V-M"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-E-A-Q-K-T-V-R-T-L-T-G-R-V-V-S-D-K-M-D-K-T-V-T-V-L-I-E-R-R-V-K-H-P-I-Y-G-K-Y-V-K-R-S-T-K-L-H-A-H-D-E-S-N-Q-C-R-I-G-D-L-V-T-I-R-E-T-R-P-L-A-K-T-K-A-W-T-L-V-D-I-V-E-R-A-V-E-V"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-T-Q-S-M-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-G-I-G-D-I-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-Q-V-M-T-A-V-V-V-R-T-K-H-G-V-R-R-T-D-G-S-I-I-R-F-D-G-N-A-A-V-L-L-N-N-K-Q-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-K-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-K-I-R-R-D-D-E-V-I-V-I-A-G-K-D-K-G-K-R-G-K-V-L-K-V-L-A-D-D-R-L-V-V-G-G-V-N-L-I-K-R-H-T-K-P-N-P-M-L-G-Q-Q-G-G-I-V-E-K-E-A-P-L-H-V-S-N-V-A-I-F-N-T-E-T-S-K-A-D-R-V-G-F-K-V-E-D-G-K-K-I-R-V-F-K-S-T-Q-K-P-V-Q-A"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-R-L-K-E-I-Y-R-K-E-I-A-P-K-L-K-E-E-L-Q-L-A-N-V-M-E-V-P-R-V-T-K-I-T-L-N-M-G-L-G-E-A-V-G-D-K-K-I-I-E-N-A-V-A-D-L-E-K-I-T-G-Q-K-P-V-V-T-Y-A-R-K-S-I-A-G-F-K-I-R-E-G-W-P-I-G-V-K-V-T-L-R-S-D-R-M-Y-E-F-L-D-R-L-L-S-I-S-L-P-R-V-R-D-F-R-G-L-N-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-K-E-Q-I-I-F-P-E-I-D-Y-D-K-I-D-A-L-R-G-L-D-I-T-L-T-T-T-A-R-T-D-D-E-G-R-A-L-L-R-A-F-K-F-P-F-R-N"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-E-S-M-K-N-R-E-L-K-R-Q-L-T-V-A-K-Y-A-K-K-R-A-E-L-K-A-I-I-A-N-P-N-S-S-A-E-E-R-W-N-A-Q-V-A-L-Q-K-Q-P-R-D-A-S-A-S-R-L-R-N-R-C-R-L-T-G-R-P-H-G-F-Y-R-K-F-G-L-S-R-N-K-L-R-E-A-A-M-R-G-D-V-P-G-L-V-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-L-A-D-M-L-T-R-I-R-N-A-Q-M-A-E-K-T-V-V-S-M-P-S-S-K-L-K-A-A-V-A-K-V-L-K-D-E-G-Y-I-A-D-F-Q-I-S-S-E-V-K-P-Q-L-S-I-E-L-K-Y-F-E-G-K-P-V-I-E-E-V-K-R-I-S-R-P-G-L-R-Q-Y-K-S-V-E-Q-L-P-K-V-R-G-G-L-G-V-S-I-V-S-T-N-K-G-V-M-T-D-R-A-A-R-A-A-G-V-G-G-E-V-L-C-T-V-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-N-P-V-K-L-P-A-G-V-E-I-K-L-A-G-Q-Q-L-S-I-K-G-A-K-G-A-L-E-L-K-V-H-P-S-V-E-V-I-Q-D-S-G-E-L-R-F-A-A-R-N-G-D-Q-Q-T-R-A-M-A-G-T-T-R-A-L-V-N-N-M-V-V-G-V-S-Q-G-F-E-R-K-L-Q-L-V-G-V-G-Y-K-A-Q-A-K-G-Q-V-L-S-L-S-L-G-F-S-H-P-V-D-Y-E-L-P-A-G-I-V-A-E-T-P-S-Q-T-D-I-L-I-K-G-I-D-K-Q-L-V-G-Q-V-A-A-E-I-R-D-F-R-P-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-V-V-R-R-K-E-A-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-V-K-K-E-T-R-L-R-R-A-R-K-A-R-L-K-M-R-E-L-E-T-V-R-L-C-V-Y-R-S-S-Q-H-I-Y-A-Q-V-I-A-A-D-G-G-K-V-L-A-S-A-S-T-L-D-K-D-L-R-E-G-A-T-G-N-I-D-A-A-K-K-V-G-Q-L-V-A-E-R-A-K-A-A-G-V-T-Q-V-A-F-D-R-S-G-F-K-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-G-G-L-E-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-L-N-D-L-R-S-A-P-G-A-R-R-E-K-H-R-P-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-L-T-S-R-S-G-G-K-V-A-P-G-F-E-G-G-Q-Q-P-L-H-R-R-L-P-K-F-G-F-V-S-L-K-A-M-D-R-A-E-V-R-T-S-E-L-A-K-V-E-G-D-V-V-S-L-Q-T-L-K-D-A-N-L-I-N-Q-H-V-Q-R-V-K-V-M-L-S-G-E-V-G-R-A-V-T-L-K-G-I-A-A-T-K-G-A-R-A-A-I-E-A-A-G-G-K-F-E-D"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-D-N-K-H-T-V-I-S-L-T-Y-I-Y-G-V-G-R-T-T-A-Q-S-I-C-A-A-T-G-V-N-P-A-A-K-I-K-D-L-S-D-E-Q-I-D-Q-L-R-N-E-V-A-K-I-T-T-E-G-D-L-R-R-E-I-N-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-R-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-P-A-A-R-P-R-K-K-V-K-K-T-V-V-D-G-I-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-S-W-A-T-S-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-R-A-G-Q-A-A-L-E-Y-G-L-K-N-L-D-V-N-V-K-G-P-G-P-G-R-E-S-A-V-R-A-L-N-A-C-G-Y-K-I-A-S-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule PhzA1 has a role in the biosynthesis of the phenazine during planktonic growth ### SEQUENCE -M-N-G-Q-R-Y-R-E-T-P-L-D-I-E-R-L-R-R-L-N-R-A-T-V-E-R-Y-M-A-M-K-G-A-E-R-L-Q-R-H-S-L-F-V-E-D-G-C-A-G-N-W-T-T-E-S-G-E-P-L-V-F-R-G-H-E-S-L-R-R-L-A-E-W-L-E-R-C-F-P-D-W-E-W-H-N-V-R-I-F-E-T-E-D-P-N-H-F-W-V-E-C-D-G-R-G-K-A-L-V-P-G-Y-P-Q-G-Y-C-E-N-H-Y-I-H-S-F-E-L-E-N-G-R-I-K-R-N-R-E-F-M-N-P-I-Q-K-L-R-A-L-G-I-A-V-P-Q-I-K-R-D-G-I-P-T"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-G-A-H-D-T-K-V-I-D-S-R-L-V-A-E-G-D-Q-V-R-R-R-R-E-C-L-A-C-G-E-R-F-T-T-F-E-T-A-E-L-V-M-P-R-L-I-K-Q-D-G-S-R-Q-P-F-D-E-D-K-L-R-A-G-M-Q-R-A-L-E-K-R-P-V-S-V-E-R-L-E-A-A-I-G-H-I-K-H-Q-L-R-A-T-G-E-R-E-I-K-S-R-V-L-G-E-L-V-M-A-E-L-Q-K-L-D-E-V-A-Y-I-R-F-A-S-V-Y-R-R-F-Q-D-L-N-E-F-R-E-E-I-E-R-L-A-R-E-P-A-K-E"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-N-Q-D-S-G-N-P-A-A-K-P-P-K-G-K-T-A-A-R-R-K-A-R-S-L-A-V-Q-A-L-Y-S-W-Q-I-A-G-Q-P-L-H-E-I-E-A-Q-F-R-T-D-N-D-F-S-E-V-D-G-A-Y-F-H-E-I-L-H-G-V-P-R-Q-K-S-E-L-D-S-T-F-E-P-C-L-D-R-P-L-A-E-I-D-P-V-E-L-A-I-L-R-L-S-T-Y-E-L-R-N-R-I-D-V-P-Y-K-V-V-I-N-E-G-I-E-L-A-K-T-F-G-A-T-D-G-H-K-F-V-N-G-V-L-D-K-L-A-P-R-L-R-A-A-E-L-R-G-G-K-R"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-R-K-K-T-L-D-F-E-Q-S-L-T-E-L-Q-T-L-V-E-R-L-E-S-G-E-L-S-L-E-E-S-L-G-A-F-E-Q-G-I-R-L-T-R-E-C-Q-T-S-L-S-Q-A-E-Q-K-V-Q-I-L-L-E-R-D-G-E-L-S-E-A-P-F-D-A-E-G-D-E-A"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-R-L-R-L-I-A-V-G-S-R-M-P-R-W-V-E-E-G-W-Q-E-Y-V-K-R-L-P-A-E-L-S-L-E-L-V-E-I-P-L-N-T-R-G-K-N-A-D-V-A-R-L-I-R-Q-E-G-E-A-M-L-A-R-V-Q-P-G-E-R-V-V-T-L-E-V-E-G-R-P-W-S-T-E-Q-L-A-R-E-L-D-R-W-R-L-D-A-R-T-V-N-L-M-V-G-G-P-E-G-L-A-P-E-V-C-A-R-S-E-Q-R-W-S-L-S-P-L-T-L-P-H-P-L-V-R-I-L-V-G-E-Q-I-Y-R-A-W-T-V-L-S-G-H-P-Y-H-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-P-L-E-L-D-L-Q-V-A-S-A-A-P-D-L-P-S-E-A-Q-F-R-A-W-C-E-L-A-L-R-Q-R-P-E-S-E-L-T-I-R-L-V-D-E-A-E-G-L-E-L-N-S-T-Y-R-H-K-D-Y-A-T-N-V-L-S-F-P-A-D-V-P-D-E-L-L-D-I-P-L-L-G-D-L-V-I-C-A-P-V-V-A-R-E-A-L-E-Q-R-K-P-L-Q-A-H-W-A-H-L-V-I-H-G-C-L-H-L-L-G-Y-D-H-I-D-D-A-E-A-E-E-M-E-T-L-E-R-E-L-L-A-E-L-G-H-P-D-P-Y-A-C-D-D-E-E-P-P-S-K-E-K"} +{"text": "### FUNCTION Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA ### SEQUENCE -M-A-K-A-P-P-S-E-P-K-L-L-L-F-N-K-P-F-D-V-L-T-Q-F-N-D-E-Q-G-R-S-T-L-K-D-F-I-P-V-P-G-V-Y-P-A-G-R-L-D-R-D-S-E-G-L-L-L-L-T-N-D-G-R-L-Q-A-R-I-A-D-P-R-H-K-L-P-K-T-Y-W-V-Q-V-E-G-T-P-D-E-E-Q-L-R-R-L-R-E-G-V-T-L-N-D-G-P-T-L-P-A-E-A-R-L-L-D-E-P-T-L-W-E-R-V-P-P-V-R-F-R-K-S-V-P-T-H-W-L-E-L-V-I-R-E-G-R-N-R-Q-V-R-R-M-T-A-A-V-G-L-P-T-L-R-L-V-R-V-R-I-G-P-W-S-L-D-G-L-G-L-G-E-W-R-E-V-P-A-R-L-D"} +{"text": "### FUNCTION Catalyzes the transfer of an acetyl group from acetyl coenzyme A and the peptide antibiotics polymyxin B and colistin Other substrates like dopamine, serotonin, puromycin, chloramphenicol, D-glucosamine, glycine and N-alpha-acetyl-L-glutamine are used and displayed lower activity ### SEQUENCE -M-N-A-N-L-P-P-S-A-I-S-E-L-H-G-P-R-L-L-L-R-A-W-R-D-S-D-R-E-A-F-A-E-M-C-A-D-P-Q-V-M-E-F-F-P-S-V-L-D-R-A-Q-S-D-A-L-V-D-R-V-Q-A-H-F-A-E-R-G-Y-G-P-W-A-L-E-L-P-G-E-A-A-F-I-G-F-T-G-L-F-D-V-T-M-D-V-H-F-A-P-T-V-E-I-G-W-R-L-A-P-A-Y-W-G-R-G-L-A-R-E-A-A-E-T-A-L-D-F-A-F-E-R-L-R-L-P-E-V-V-A-F-T-T-P-P-N-R-R-S-W-G-L-M-E-R-L-G-M-R-R-D-P-A-E-D-F-D-H-P-L-L-A-A-D-H-P-M-R-R-H-I-L-Y-R-V-D-A-A-R-W-A-E-R"} +{"text": "### FUNCTION Plays an essential role by modulating the expression of hundreds of genes including quorum sensing system genes and oxidative stress resistance genes under both aerobic and anaerobic conditions ### SEQUENCE -M-M-F-E-R-S-P-D-D-P-L-P-L-V-Y-A-C-S-G-C-S-N-V-A-Q-L-A-N-D-L-A-L-R-L-D-R-A-R-L-A-E-M-S-C-I-A-G-V-G-G-D-V-P-L-L-V-R-R-A-R-S-G-R-P-I-L-A-L-D-G-C-P-L-H-C-V-K-G-C-L-A-R-H-E-V-V-P-T-L-H-L-T-L-S-E-H-G-L-K-K-R-Y-G-E-D-C-E-A-Q-D-A-E-R-L-F-V-E-L-E-R-L-L-T-P-G-G-K-R-R-C-E"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-G-K-P-C-H-F-A-Q-F-D-L-Q-P-A-F-L-V-D-L-D-E-L-G-Q-R-Y-R-E-L-V-R-S-V-H-P-D-R-F-A-D-A-P-E-R-E-Q-R-L-A-L-E-R-A-A-Q-L-N-E-A-Y-Q-T-L-K-S-A-P-R-R-A-L-Y-L-L-T-L-S-G-H-E-L-P-L-E-A-T-V-Q-D-P-E-F-L-L-Q-Q-M-Q-L-R-E-E-L-E-E-L-Q-D-S-A-D-L-A-G-V-A-T-F-K-R-R-L-K-A-A-Q-A-E-L-E-R-E-F-A-A-C-W-D-D-A-Q-R-R-E-E-A-E-R-L-V-R-R-M-Q-F-L-D-K-L-A-Q-E-V-R-Q-L-E-E-R-L-D-D"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-P-T-P-A-D-D-L-V-V-I-G-K-I-V-S-V-Y-G-I-R-G-E-V-K-V-Y-S-F-T-D-P-L-D-N-L-L-D-Y-R-R-W-T-L-R-R-D-G-E-I-R-Q-A-E-L-V-R-G-R-L-H-G-K-V-L-A-A-K-L-K-G-L-D-D-R-E-E-A-R-T-F-T-G-Y-E-I-C-I-P-R-S-E-L-P-S-L-E-E-G-E-Y-Y-W-H-Q-L-E-G-L-K-V-I-D-Q-G-R-Q-L-L-G-V-I-D-H-L-L-E-T-G-A-N-D-V-M-V-V-K-P-C-A-G-S-L-D-D-R-E-R-L-L-P-Y-T-G-Q-C-V-L-S-I-D-L-A-A-G-E-M-R-V-D-W-D-A-D-F"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-T-N-K-I-I-Q-Q-I-E-A-E-Q-M-N-K-E-I-P-A-F-A-P-G-D-T-V-I-V-Q-V-K-V-K-E-G-D-R-Q-R-L-Q-A-F-E-G-V-V-I-A-K-R-N-R-G-L-N-S-A-F-T-V-R-K-I-S-N-G-V-G-V-E-R-T-F-Q-T-Y-S-P-I-V-D-S-L-S-V-K-R-R-G-D-V-R-K-A-K-L-Y-Y-L-R-A-L-S-G-K-A-A-R-I-K-E-K-L-V"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-L-R-S-P-Y-W-L-F-V-V-L-I-L-A-L-A-G-L-Q-Y-R-L-W-V-G-D-G-S-L-A-Q-V-R-D-L-Q-K-Q-I-A-D-Q-H-G-E-N-E-R-L-L-E-R-N-R-I-L-E-A-E-V-A-E-L-K-K-G-T-E-T-V-E-E-R-A-R-H-E-L-G-M-V-K-D-G-E-T-L-Y-Q-L-A-K"} +{"text": "### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-T-F-V-V-T-D-N-C-I-K-C-K-Y-T-D-C-V-E-V-C-P-V-D-C-F-Y-E-G-P-N-F-L-V-I-H-P-D-E-C-I-D-C-A-L-C-E-P-E-C-P-A-Q-A-I-F-S-E-D-E-V-P-E-N-M-Q-E-F-I-E-L-N-S-E-L-A-E-V-W-P-N-I-T-E-K-K-D-A-L-P-D-A-E-E-W-D-G-V-A-G-K-L-Q-H-L-E-R"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-T-E-L-A-L-I-L-V-S-A-I-L-V-N-N-F-V-L-V-Q-F-L-G-L-C-P-F-M-G-V-S-R-K-I-E-T-A-I-G-L-S-L-A-T-T-F-V-L-T-L-A-A-M-C-S-H-I-L-Q-R-Y-V-L-R-P-L-D-L-E-Y-L-R-T-I-G-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-L-V-K-K-T-S-P-L-L-Y-R-V-L-G-I-F-L-P-L-I-T-T-N-C-I-V-L-G-V-A-L-L-N-A-N-K-A-E-Y-G-F-L-Q-A-T-T-Q-G-F-G-A-G-L-G-F-S-L-V-L-V-L-F-A-A-L-R-E-R-I-A-I-A-D-V-P-A-P-F-R-G-A-A-I-G-M-I-T-A-G-L-M-S-L-A-F-M-G-F-S-G-L-V-R-P"} +{"text": "### FUNCTION Probable electron transporter ### SEQUENCE -M-K-V-A-I-L-S-G-S-V-Y-G-T-A-E-E-V-A-R-H-A-Q-K-L-L-S-A-A-G-L-E-A-S-H-L-P-R-A-S-L-D-E-L-K-A-F-A-P-E-A-F-L-V-V-T-S-T-T-G-M-G-E-L-P-D-N-L-Q-P-L-Y-Y-A-I-R-D-Q-L-P-A-W-H-G-L-P-G-G-V-I-G-L-G-D-S-S-Y-G-D-T-F-C-G-G-G-E-Q-V-R-E-L-F-G-E-L-G-V-R-E-V-L-P-M-L-R-L-D-A-S-E-T-V-T-P-E-T-D-A-E-P-W-L-A-E-F-A-A-A-L-K-G"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-L-D-F-F-R-S-R-K-S-Q-N-S-A-S-I-A-K-E-R-L-Q-I-I-V-A-H-E-R-G-Q-R-A-Q-P-D-Y-L-P-Q-L-Q-K-D-L-L-E-V-I-R-K-Y-V-P-I-D-Q-E-Q-I-Q-V-E-L-E-N-Q-G-N-C-S-I-L-E-L-N-I-T-L-P-D-R"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-Q-F-I-D-F-I-P-L-I-L-F-F-I-V-Y-K-I-D-P-Q-N-V-E-F-A-G-F-N-L-S-G-I-Y-G-A-T-A-T-L-I-L-A-S-V-I-V-Y-G-A-L-W-L-K-H-R-H-L-E-K-S-Q-W-F-T-L-G-A-C-L-V-L-G-G-L-T-L-A-F-H-E-D-T-F-L-K-W-K-A-P-L-V-N-W-L-F-A-L-A-F-A-G-S-H-F-I-G-D-K-P-M-I-Q-R-I-M-G-H-A-I-Q-L-P-Q-G-L-W-V-R-L-N-I-A-W-V-V-F-F-L-V-C-G-F-A-N-L-Y-V-V-F-T-Y-P-N-F-W-V-D-F-K-V-F-G-S-L-G-M-T-L-L-F-L-I-G-Q-G-L-F-L-A-R-H-L-H-D-A-D-T-G-E-K-P-K-D"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-P-D-L-I-L-A-S-S-S-P-Y-R-R-E-L-L-T-R-L-R-L-P-F-E-S-A-S-P-D-I-D-E-S-H-R-A-G-E-S-A-E-E-L-V-R-R-L-S-A-S-K-A-E-A-L-A-G-R-Y-P-Q-H-L-V-I-G-S-D-Q-V-A-V-L-D-G-N-I-L-G-K-P-H-T-P-E-R-A-I-Q-Q-L-R-D-A-S-G-K-S-V-T-F-L-T-G-L-A-L-L-N-S-A-S-R-R-I-Q-V-A-C-V-P-F-T-V-H-F-R-H-L-D-E-S-R-I-R-R-Y-V-E-A-E-R-P-L-D-C-A-G-S-F-K-A-E-G-L-G-V-S-L-F-R-S-T-E-G-E-D-A-T-S-L-V-G-L-P-L-I-R-L-V-D-M-L-L-E-E-G-V-E-I-P"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-N-P-V-S-L-I-F-L-A-F-A-M-S-T-D-A-F-A-A-A-I-G-K-G-S-S-L-D-R-P-R-L-S-E-A-L-R-T-G-I-I-F-G-V-I-E-A-I-T-P-L-V-G-W-L-L-G-Q-A-A-S-Q-F-V-A-D-W-D-H-W-I-A-F-V-L-L-V-L-L-G-L-H-M-I-H-N-G-L-R-A-D-H-A-T-E-Q-E-K-P-G-Q-H-S-F-W-I-L-A-V-T-A-L-A-T-S-I-D-A-L-A-V-G-V-G-L-A-F-V-D-V-N-I-F-L-A-A-G-A-I-G-L-A-T-M-T-M-V-T-L-G-T-M-L-G-R-A-L-G-A-V-T-G-K-R-A-E-M-V-G-G-V-V-L-I-L-V-G-A-T-I-L-Y-E-H-L-S-A-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-S-R-Y-R-P-P-R-T-A-G-T-P-L-I-T-P-E-G-A-A-R-L-R-A-E-L-H-E-L-W-H-V-R-R-P-Q-V-T-Q-A-V-S-E-A-A-A-L-G-D-R-S-E-N-A-E-Y-I-Y-G-K-K-M-L-R-E-I-D-S-R-V-R-F-L-R-K-R-L-E-N-L-K-V-V-G-E-R-P-A-D-P-N-R-V-Y-F-G-A-W-V-T-L-E-D-E-D-G-E-Q-A-R-Y-R-I-V-G-P-D-E-L-D-L-R-N-N-Q-I-S-I-D-S-P-L-A-R-A-L-V-G-K-E-L-D-A-E-V-L-V-R-T-P-A-G-E-K-L-W-F-V-V-E-I-E-Y-P-P-A-P"} +{"text": "### FUNCTION Immunity protein that plays a role in preventing early activation of toxin Tse4 ### SEQUENCE -M-T-T-S-S-G-S-R-I-G-G-L-L-H-A-S-L-F-S-L-L-G-L-G-L-L-L-A-G-G-F-K-T-V-E-R-Y-H-F-L-R-T-A-Q-E-A-Q-G-T-V-S-A-L-N-A-G-G-S-H-P-Q-I-D-F-T-S-V-S-G-E-R-I-S-Y-P-Q-G-G-F-I-F-G-Y-Q-V-G-E-P-V-R-V-L-Y-E-A-G-R-P-A-A-S-A-I-V-D-D-A-G-A-L-W-G-T-G-A-F-L-C-G-F-G-A-L-F-G-I-V-G-F-R-G-L-L-G-L-R-S-S-Q-P-T-S-K-G-H"} +{"text": "### FUNCTION General inhibitor of family S1 serine proteases ### SEQUENCE -M-K-A-L-L-I-A-A-G-V-A-A-L-S-S-T-A-M-A-A-K-L-D-E-K-V-P-Y-P-K-A-D-A-G-F-T-R-Q-V-I-H-L-P-K-Q-D-A-E-D-A-F-K-V-E-I-I-A-G-K-T-L-E-A-D-C-N-Q-Q-R-L-G-G-E-L-E-E-H-T-L-E-G-W-G-Y-S-Y-Y-R-L-D-K-V-S-G-P-M-S-T-M-M-A-C-P-G-Q-K-K-E-Q-R-F-I-P-V-V-G-E-G-F-L-L-C-Y-N-S-K-L-P-I-V-V-Y-A-P-K-D-V-E-V-R-Y-R-I-W-S-A-S-E-K-V-E-K-A-V-S-E"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-I-I-K-R-E-M-R-Q-D-K-R-A-Q-P-K-P-P-I-N-E-N-I-S-A-R-E-V-R-L-I-G-A-D-G-Q-Q-V-G-V-V-S-I-D-E-A-I-R-L-A-E-E-A-K-L-D-L-V-E-I-S-A-D-A-V-P-P-V-C-R-I-M-D-Y-G-K-H-L-F-E-K-K-K-Q-A-A-V-A-K-K-N-Q-K-Q-A-Q-V-K-E-I-K-F-R-P-G-T-E-E-G-D-Y-Q-V-K-L-R-N-L-V-R-F-L-S-E-G-D-K-A-K-V-S-L-R-F-R-G-R-E-M-A-H-Q-E-L-G-M-E-L-L-K-R-V-E-A-D-L-V-E-Y-G-T-V-E-Q-H-P-K-L-E-G-R-Q-L-M-M-V-I-A-P-K-K-K-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-R-R-H-K-K-I-L-K-L-A-K-G-Y-Y-G-A-R-S-R-V-F-R-V-A-K-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-A-L-W-I-A-R-I-N-A-G-A-R-Q-N-G-L-S-Y-S-R-L-I-A-G-L-K-K-A-A-I-E-I-D-R-K-V-L-A-D-L-A-V-N-E-K-A-A-F-T-A-I-V-E-K-A-K-A-S-L-A"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur ### SEQUENCE -M-E-F-A-F-Y-F-A-A-G-V-A-V-L-A-T-L-R-V-I-T-N-S-N-P-V-H-A-L-L-Y-L-I-I-S-L-L-A-I-S-M-T-F-F-S-L-G-A-P-F-A-G-A-L-E-I-I-V-Y-A-G-A-I-M-V-L-F-V-F-V-V-M-M-L-N-L-G-P-A-V-V-E-Q-E-R-K-W-L-T-P-G-I-W-V-G-P-S-A-L-A-L-V-L-L-V-E-L-L-V-V-L-A-R-T-P-S-G-A-G-I-G-H-T-T-V-D-A-K-A-V-G-I-S-L-Y-G-P-Y-L-L-V-V-E-L-A-S-M-L-L-L-A-A-L-V-A-A-Y-H-L-G-R-Q-D-A-K-Q"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-K-F-A-I-A-L-F-D-P-P-H-S-P-A-A-R-R-A-L-R-F-S-E-A-A-L-A-G-G-H-E-I-V-R-L-F-F-Y-Q-D-G-V-H-S-A-S-A-N-V-V-S-G-Q-D-E-F-D-L-P-A-A-W-R-E-L-V-E-R-N-G-L-D-A-V-V-C-I-A-A-A-L-R-R-G-V-L-N-A-E-E-A-E-R-Y-G-R-P-G-A-N-L-G-A-P-W-E-L-S-G-L-G-Q-L-H-E-A-A-Q-S-A-D-R-L-V-C-F-G-G-D-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-K-L-R-F-T-T-D-H-E-W-L-R-Q-D-D-D-G-L-L-T-V-G-I-T-A-Y-A-Q-D-A-L-G-D-V-V-F-V-Q-L-P-E-L-G-E-H-A-A-G-S-E-V-A-V-L-E-S-V-K-A-A-S-N-I-L-M-P-L-D-G-E-V-V-A-I-N-D-A-L-P-D-A-P-E-L-V-N-Q-D-P-L-G-E-A-W-F-F-R-F-R-P-A-D-A-G-A-W-E-K-L-L-D-Q-A-A-Y-D-R-L-L-N-A-N-A-D-A"} +{"text": "### FUNCTION Catalyzes the transfer of an acetyl group from acetyl coenzyme A -acetylspermidine, 7-aminocephalosporanic acid, colistin and thiamine ### SEQUENCE -M-D-Y-R-I-R-T-S-R-D-E-D-A-A-L-L-P-A-I-E-R-S-A-G-E-S-F-R-L-L-P-E-L-A-W-I-A-D-A-G-V-A-G-V-D-F-H-R-R-L-I-E-R-G-S-H-W-L-A-E-D-A-D-G-Q-P-V-G-F-L-A-A-E-R-C-A-D-E-L-H-I-A-E-L-S-I-A-Q-A-H-Q-Q-Q-G-L-G-R-R-L-L-E-R-A-V-T-Y-A-H-A-S-H-C-R-A-L-T-L-T-T-F-C-D-V-P-W-N-A-P-F-Y-A-R-L-G-F-Q-R-L-T-W-Q-E-A-G-E-R-L-R-A-I-L-G-H-E-Q-E-I-G-F-A-A-D-S-R-C-A-M-R-L-V-L"} +{"text": "### FUNCTION Positive regulator of the bkd operon for branched-chain keto acid dehydrogenase complex ### SEQUENCE -M-A-E-L-D-R-I-D-L-K-I-L-R-A-L-A-D-D-G-R-L-S-W-R-D-L-A-Q-K-V-G-L-S-L-T-P-T-L-R-R-V-R-R-L-E-E-E-H-Y-I-Q-G-Y-F-A-R-L-D-E-E-R-L-S-G-A-M-S-V-F-V-S-V-S-L-E-K-Q-T-G-D-Y-L-A-R-F-E-E-R-I-V-D-A-P-Q-V-M-S-C-F-Q-M-T-G-D-A-D-Y-M-L-R-V-V-V-K-D-L-A-A-Y-Q-A-F-L-T-N-T-L-T-C-I-P-G-V-A-G-I-K-S-A-F-A-L-K-S-V-M-L-R-S-A-P-P-L"} +{"text": "### FUNCTION May be involved in the regulation of the production of pyocyanine, one of the major virulence factors secreted by Paeruginosa, and other virulence factors ### SEQUENCE -M-A-Q-H-Q-G-G-K-G-N-F-A-E-D-P-K-R-A-S-E-A-G-K-K-G-G-Q-A-S-G-G-N-F-K-N-D-P-Q-R-A-S-E-A-G-K-K-G-G-Q-R-S-H-G-G-N"} +{"text": "### FUNCTION Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide ### SEQUENCE -M-Q-H-S-Q-V-S-P-N-A-R-Q-Q-L-A-E-T-V-V-L-N-K-A-R-L-G-L-S-W-Q-D-L-A-D-G-T-G-L-A-L-T-F-V-T-A-A-L-L-G-Q-H-A-L-P-E-A-A-A-R-K-V-A-A-Q-L-G-L-D-D-D-A-V-L-L-L-Q-S-I-P-L-R-G-S-I-P-G-G-I-P-S-D-P-T-I-Y-R-F-Y-E-M-L-Q-V-Y-G-S-T-L-K-A-L-V-H-E-Q-F-G-D-G-I-I-S-A-I-N-F-K-L-D-I-K-K-V-E-D-P-E-G-G-S-R-A-V-I-T-L-D-G-K-Y-L-P-T-K-P-F"} +{"text": "### FUNCTION Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone biosynthetic pathway ### SEQUENCE -M-S-L-P-S-L-D-S-V-P-M-L-R-R-G-F-R-F-Q-F-E-P-A-Q-D-C-H-V-L-L-Y-P-E-G-M-V-K-L-N-D-S-A-G-E-I-L-K-L-V-D-G-R-R-D-V-A-A-I-V-A-A-L-R-E-R-F-P-E-V-P-G-I-D-E-D-I-L-A-F-L-E-V-A-H-A-Q-F-W-I-E-L-Q"} +{"text": "### FUNCTION Acetylates the N-terminal alanine of ribosomal protein uS5 ### SEQUENCE -M-P-G-N-R-R-Q-V-P-I-L-H-R-D-A-D-F-L-L-R-A-L-Q-P-D-D-F-V-R-T-S-R-Y-E-N-A-N-R-E-H-L-A-P-W-E-P-L-R-D-P-G-Y-F-S-V-D-N-A-R-A-R-T-L-L-Q-V-A-S-M-D-E-G-E-A-L-L-L-L-L-L-D-P-D-D-G-E-V-L-G-R-C-S-Y-T-N-I-V-R-G-V-F-Q-A-C-H-L-G-F-S-L-A-A-A-A-Q-G-R-G-L-M-A-R-A-L-R-V-A-N-R-Y-C-F-E-Q-L-G-L-H-R-I-M-A-S-H-L-P-R-N-A-R-S-E-R-L-L-E-S-L-G-F-E-K-E-G-Y-A-R-A-Y-L-K-I-A-G-V-W-E-D-H-V-L-R-A-L-V-D-A-P-R"} +{"text": "### FUNCTION Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control PhzA2 has a role in the biosynthesis of the phenazine during both planktonic growth and biofilm development, and in host infection during biofilm development ### SEQUENCE -M-R-E-Y-Q-R-L-K-G-F-T-D-N-L-E-L-R-R-R-N-R-A-T-V-E-H-Y-M-R-M-K-G-A-E-R-L-Q-R-H-S-L-F-V-E-D-G-C-A-G-N-W-T-T-E-S-G-E-P-L-V-F-R-G-H-E-S-L-R-R-L-A-E-W-L-E-R-C-F-P-D-W-E-W-H-N-V-R-I-F-E-T-E-D-P-N-H-F-W-V-E-C-D-G-R-G-K-A-L-V-P-G-Y-P-Q-G-Y-C-E-N-H-Y-I-H-S-F-E-L-E-N-G-R-I-K-R-N-R-E-F-M-N-P-M-Q-K-L-R-A-L-G-I-A-V-P-Q-I-K-R-D-G-I-P-T"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-S-A-I-T-I-T-E-A-A-Q-A-Y-L-A-E-L-L-E-K-Q-S-T-P-G-I-G-I-R-I-F-I-T-Q-P-G-T-Q-Y-A-E-T-C-I-A-Y-C-K-P-G-E-E-K-V-E-D-T-A-I-A-L-K-D-F-T-A-W-I-D-A-V-S-E-P-F-L-E-D-A-V-V-D-Y-A-T-D-R-M-G-G-Q-L-T-I-K-A-P-N-A-K-V-P-M-V-N-E-D-S-P-I-T-E-R-I-N-Y-Y-L-Q-T-E-I-N-P-G-L-A-S-H-G-G-Q-V-S-L-V-D-V-V-E-D-N-I-A-V-L-R-F-G-G-G-C-Q-G-C-G-M-V-D-M-T-L-K-D-G-V-E-K-T-L-I-E-R-I-P-E-L-K-G-V-R-D-V-T-D-H-S-N-K-E-N-A-Y-Y"} +{"text": "### FUNCTION Immunity protein that plays a role in preventing early activation of toxin Tse1 Binds to a large surface of Tse1 and thereby occludes the active site to specifically inhibits enzyme activity by forming a hydrogen bond with the catalytic diad ### SEQUENCE -M-K-L-L-A-G-S-F-A-A-L-F-L-S-L-S-A-Q-A-A-D-C-T-F-T-Q-L-E-I-V-P-Q-F-G-S-P-N-M-F-G-G-E-D-E-H-V-R-V-M-F-S-N-E-D-P-N-D-D-N-P-D-A-F-P-E-P-P-V-Y-L-A-D-R-D-S-G-N-D-C-R-I-E-D-G-G-I-W-S-R-G-G-V-F-L-S-Q-D-G-R-R-V-L-M-H-E-F-S-G-S-S-A-E-L-V-S-Y-D-S-A-T-C-K-V-V-H-R-E-D-I-S-G-Q-R-W-A-V-D-K-D-G-L-R-L-G-Q-K-C-S-G-E-S-V-D-S-C-A-K-I-V-K-R-S-L-A-P-F-C-Q-T-A-K-K"} +{"text": "### FUNCTION Oxygen-binding protein May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes The oxygen-binding site contains two iron atoms ### SEQUENCE -M-A-H-L-V-W-Q-D-D-L-N-T-G-I-Q-V-I-D-N-Q-H-K-R-I-V-E-M-I-N-H-L-H-D-A-Q-Q-G-K-E-H-A-A-I-A-E-V-I-E-E-L-V-D-Y-T-L-S-H-F-A-F-E-E-T-L-M-E-D-A-G-Y-Q-F-S-R-A-H-K-K-I-H-E-L-F-I-R-R-V-S-E-Y-R-V-R-F-Q-A-G-E-D-V-G-D-E-L-K-G-L-L-S-R-W-L-F-N-H-I-R-N-D-D-A-G-Y-V-D-A-V-R-H-S-M-S-E-L-V-K-D-K-S-E-G-G-W-L-S-R-S-M-K-R-F-F-G"} +{"text": "### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-T-H-S-V-D-A-I-L-D-A-T-G-L-N-C-P-E-P-V-M-M-L-H-N-K-V-R-D-L-A-P-G-G-L-L-K-V-I-A-T-D-P-S-T-R-R-D-I-P-K-F-C-V-F-L-G-H-E-L-V-E-Q-Q-E-E-A-G-T-Y-L-Y-W-I-R-K-K-A-D"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-F-S-P-L-I-R-Q-L-I-E-S-L-R-I-L-P-G-V-G-Q-K-S-A-Q-R-M-A-L-M-L-L-E-R-D-R-S-G-G-L-K-L-A-Q-A-L-T-A-A-M-E-G-V-G-H-C-R-Q-C-R-T-L-S-E-E-E-L-C-P-Q-C-A-D-P-R-R-D-D-S-L-L-C-V-V-E-G-P-L-D-V-F-A-V-E-Q-T-G-Y-R-G-R-Y-F-V-L-K-G-H-L-S-P-L-D-G-L-G-P-E-A-I-G-I-P-E-L-E-A-R-I-R-D-G-A-F-S-E-V-I-L-A-T-N-P-T-V-E-G-E-A-T-A-H-Y-I-A-Q-L-L-A-G-R-G-L-T-L-S-R-I-A-H-G-V-P-L-G-G-E-L-E-L-V-D-G-G-T-L-A-H-A-L-A-G-R-R-P-I-S"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-K-G-G-M-A-G-L-M-K-Q-A-Q-Q-M-Q-E-K-M-Q-K-M-Q-E-E-L-A-N-A-E-V-T-G-Q-S-G-A-G-L-V-S-V-V-M-T-G-R-H-D-V-K-R-V-S-L-D-D-S-L-M-Q-E-D-K-E-I-L-E-D-L-I-A-A-A-V-N-D-A-V-R-K-I-E-Q-N-N-Q-E-K-M-S-G-F-T-S-G-M-Q-L-P-P-G-F-K-M-P-F"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 5-hydroxyisourate ### SEQUENCE -M-S-A-S-G-R-P-Q-P-M-G-R-L-T-T-H-V-L-D-S-A-H-G-C-P-G-H-G-I-K-I-E-L-Y-R-V-E-G-Q-Q-L-E-L-I-A-T-T-L-T-N-H-D-G-R-C-D-Q-P-V-L-Q-G-E-D-F-R-P-G-V-Y-Q-L-V-F-N-A-G-D-Y-Y-R-A-R-G-V-Q-L-P-E-P-A-F-L-D-Q-V-V-L-R-F-G-I-A-S-A-D-D-H-Y-H-V-P-L-L-I-S-P-Y-S-Y-S-T-Y-R-G-S"} +{"text": "### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate -ureidoglycolate, generating urea and glyoxylate Involved in the utilization of allantoin as nitrogen source ### SEQUENCE -M-R-T-L-K-I-E-P-L-T-K-E-A-F-A-P-F-G-D-V-I-E-T-A-G-S-D-Y-F-M-I-N-N-G-S-T-R-R-Y-H-K-L-A-T-V-E-T-A-Q-P-E-D-N-A-I-I-S-I-F-S-A-E-K-L-E-M-P-L-R-I-R-M-L-E-R-H-P-L-G-S-Q-A-F-I-P-L-L-G-N-P-F-L-V-V-V-A-P-L-G-D-V-P-V-P-G-L-V-R-A-F-L-T-N-G-R-Q-G-V-N-Y-H-R-G-V-W-H-H-P-V-L-T-I-E-K-R-D-D-F-L-V-V-D-R-S-G-S-G-N-N-C-D-E-H-F-F-T-E-D-E-Q-L-L-L-D-P-Q-S-N-Q"} +{"text": "### FUNCTION Required for the biogenesis of c-type cytochromes Possible subunit of a heme lyase ### SEQUENCE -M-K-R-F-L-A-T-A-L-L-G-L-A-L-C-G-V-A-R-A-A-I-D-T-Y-E-F-A-S-D-A-E-R-E-R-F-R-N-L-T-Q-E-L-R-C-P-K-C-Q-N-Q-D-I-A-D-S-N-A-P-I-A-A-D-L-R-K-Q-I-Y-G-Q-L-Q-Q-G-K-S-D-G-E-I-V-D-Y-M-V-A-R-Y-G-D-F-V-R-Y-K-P-P-V-N-E-R-T-W-L-L-W-F-G-P-G-A-L-L-L-F-G-V-L-V-I-G-V-I-V-L-R-R-R-R-T-A-A-K-V-Q-T-T-L-S-A-E-E-Q-A-R-L-A-N-L-L-K-N-D-K"} +{"text": "### FUNCTION Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ### SEQUENCE -M-S-F-E-S-F-G-D-F-L-A-M-G-H-H-G-P-Y-V-W-S-A-Y-G-I-S-L-L-V-L-A-I-N-V-A-E-P-L-L-A-R-R-R-Y-L-Q-E-E-A-R-R-L-R-R-E-A-Q-Q"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-A-D-E-T-E-L-K-R-L-Y-W-H-S-R-R-G-M-L-E-L-D-V-L-L-V-P-F-V-Q-E-V-Y-P-G-L-D-A-E-D-Q-A-R-F-R-K-L-L-E-C-E-D-Q-D-M-F-G-W-F-M-Q-R-G-E-P-E-D-A-D-L-R-R-M-V-R-M-I-L-D-R-V-Q-P-D"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-I-E-T-F-T-P-T-P-L-L-F-T-P-G-A-A-N-K-V-K-T-L-I-D-E-E-G-N-P-R-L-K-L-R-V-F-V-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-D-I-A-D-D-D-T-V-I-E-R-D-G-V-G-L-V-V-D-P-M-S-F-Q-Y-L-A-G-S-E-V-D-Y-Q-E-G-L-E-G-S-R-F-V-I-K-N-P-N-A-A-T-T-C-G-C-G-Q-S-F-S-I"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-S-D-T-F-Q-R-I-A-P-E-Q-V-R-Q-L-R-E-N-G-A-Q-V-V-D-I-R-D-P-Q-S-F-A-V-G-H-I-S-G-S-R-H-I-D-N-H-S-V-A-D-F-I-A-A-A-D-L-D-A-P-L-V-V-V-C-Y-H-G-N-S-S-Q-S-A-A-A-Y-F-I-Q-Q-G-F-S-D-V-Y-S-L-D-G-G-F-E-L-W-R-S-V-Y-P-A-D-T-S-S-G-E-A-E"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-S-D-K-P-L-R-L-L-L-G-F-D-Y-G-T-R-Q-I-G-V-A-V-G-Q-A-V-T-G-Q-A-R-E-L-C-V-L-K-A-Q-N-G-V-P-D-W-N-R-V-E-A-L-I-K-E-W-Q-P-D-A-I-V-V-G-L-P-L-N-M-D-G-S-P-S-E-M-S-E-R-A-E-K-F-G-R-R-L-N-G-R-F-N-L-P-V-F-T-H-D-E-R-L-T-T-Y-A-A-K-G-E-R-L-A-Q-G-Q-R-D-G-Y-R-E-R-P-V-D-A-L-A-A-A-L-L-L-E-G-W-L-A-E-H-P-D"} +{"text": "### FUNCTION Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'--3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism ### SEQUENCE -M-E-T-L-T-F-E-F-P-A-G-A-P-A-R-G-R-A-L-A-G-C-V-G-S-G-D-L-E-V-L-L-E-P-A-A-G-G-A-L-S-I-Q-V-V-T-S-V-N-G-S-G-P-R-W-Q-Q-L-F-A-R-V-F-A-A-S-T-A-P-A-A-S-I-R-I-H-D-F-G-A-T-P-G-V-V-R-L-R-L-E-Q-A-L-E-E-A-G-H-D"} +{"text": "### FUNCTION Involved in the degradation of beta-alanine ### SEQUENCE -M-S-G-R-P-Q-A-V-P-T-V-Q-V-D-N-A-E-V-I-V-T-E-W-R-F-A-P-G-A-E-T-G-R-H-R-H-G-H-D-Y-V-V-V-P-L-T-D-G-T-L-L-L-E-T-P-E-G-D-R-H-A-P-L-V-A-G-Q-A-Y-F-R-K-A-G-V-E-H-N-V-I-N-A-S-A-H-E-V-V-F-V-E-T-E-I-K"} +{"text": "### FUNCTION Plays an essential role in toxin Tse6 delivery to target cells and specifically in the loading of Tse6 onto VgrG1a ### SEQUENCE -M-T-L-Y-R-L-H-E-A-D-L-E-I-P-D-A-W-Q-D-Q-S-I-N-I-F-K-L-P-A-S-G-P-A-R-E-A-S-F-V-I-S-R-D-A-S-Q-G-D-A-P-F-A-D-Y-V-A-R-Q-L-E-N-A-E-K-Q-L-P-G-F-K-L-H-K-R-W-D-I-N-I-H-G-H-A-A-V-L-L-D-Y-Q-W-Q-R-E-G-R-D-L-M-L-R-Q-V-F-I-E-R-R-P-A-V-L-I-T-T-L-T-T-T-P-A-D-L-P-H-H-E-P-A-W-K-Q-A-M-Q-T-L-V-P-R-P-T-P-S"} +{"text": "### FUNCTION Immunity protein that plays a role in preventing early activation of toxin Tse6 ### SEQUENCE -M-T-P-I-E-Y-I-D-R-A-L-A-L-V-V-D-R-L-A-R-Y-P-G-Y-E-V-L-L-S-A-E-K-Q-L-Q-Y-I-R-S-V-L-L-D-R-S-L-D-R-S-A-L-H-R-L-T-L-G-S-I-A-V-K-E-F-D-E-T-D-P-E-L-S-R-A-L-K-D-A-Y-Y-V-G-I-R-T-G-R-G-L-K-V-D-L-P"} +{"text": "### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate ### SEQUENCE -M-D-R-K-T-L-D-D-T-S-K-F-L-S-Y-V-L-R-H-Q-P-E-A-I-G-L-T-L-D-G-E-G-W-A-D-I-D-A-L-I-A-G-A-A-R-D-G-R-A-L-D-R-M-L-L-G-A-V-V-E-N-N-D-K-K-R-F-A-L-S-A-D-G-Q-R-I-R-A-V-Q-G-H-S-H-A-A-V-A-I-A-Y-A-P-A-V-P-P-A-V-L-Y-H-G-T-A-S-R-F-L-D-S-I-R-E-R-G-L-V-P-G-S-R-H-H-V-H-L-S-A-R-R-A-T-A-L-E-V-G-R-R-Y-G-S-P-V-L-L-E-I-D-A-R-D-M-H-L-A-G-H-L-F-H-Q-A-E-N-G-V-W-L-T-E-R-V-P-V-R-F-I-R-E-A"} +{"text": "### FUNCTION Subunit of the V1 complex of vacuolar ### SEQUENCE -V-I-G-D-E-D-T-V-T-G-F-L-L-G-G-I-G-E-L-N-K-N-R-K-P-N-F-L-V-V-E-K-E-T-S-V-T-E-I-E-E-T-F-R-S-F-L-N-R-D-D-I-G-I-I-L-I-N-Q-F-I-A-E-M-I-R-H-V-I-D-T-H-T-I-S-I-P-A-V-L-E-I-P-S-K-E-H-P-Y-D-A-T-K-D-S-I-L-R-R-A-K-G-M-F-T-M-E-D-L-R"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-L-A-T-G-A-L-S-L-V-G-K-R-A-I-S-T-S-V-C-L-R-G-G-H-G-V-A-K-V-E-E-Y-T-L-P-A-Y-F-D-R-R-E-N-P-L-P-D-I-C-Y-V-Q-A-L-S-P-E-Q-Q-S-L-K-E-K-E-K-G-S-W-A-A-L-S-N-E-E-K-I-A-L-Y-R-I-S-F-K-Q-S-F-A-E-M-N-K-G-S-S-E-W-K-S-V-V-G-G-M-L-F-F-I-G-F-T-G-L-V-V-L-W-Q-R-K-Y-V-Y-G-A-V-P-H-T-F-D-P-E-Y-K-A-K-E-L-Q-R-M-L-D-M-R-I-N-P-V-E-G-F-S-A-H-W-D-Y-E-N-K-Q-W-K-K"} +{"text": "### FUNCTION In muscle, parvalbumin is thought to be involved in relaxation after contraction It binds two calcium ions ### SEQUENCE -M-A-F-A-G-I-L-K-D-E-D-V-A-A-A-L-K-D-C-A-A-A-D-S-F-N-Y-K-N-F-F-A-K-V-G-L-S-A-K-S-P-D-D-I-K-K-A-F-F-V-I-D-Q-D-K-S-G-F-I-E-E-D-E-L-K-L-F-L-Q-N-F-S-A-G-A-R-A-L-T-D-A-E-T-K-A-F-L-S-A-G-D-S-D-G-D-G-K-I-G-V-D-E-F-A-L-L-V-K-A"} +{"text": "### FUNCTION Plays an important role in the organization of the cytoskeleton Binds to and sequesters actin monomers ### SEQUENCE -M-A-D-K-P-D-I-S-E-V-S-Q-F-D-K-T-K-L-K-K-T-E-T-Q-E-K-N-T-L-P-T-K-E-T-I-E-Q-E-K-Q-C-E-A"} +{"text": "### FUNCTION Plays an important role in the organization of the cytoskeleton Binds to and sequesters actin monomers ### SEQUENCE -M-S-D-N-P-V-K-E-E-V-Q-Q-F-D-K-K-C-L-K-K-T-N-T-A-E-K-N-T-L-P-T-K-E-D-I-D-Q-E-K-K-A-A-E-G-G-K"} +{"text": "### FUNCTION Plays an important role in the organization of the cytoskeleton Binds to and sequesters actin monomers ### SEQUENCE -M-A-D-K-P-D-F-G-E-V-A-S-F-D-K-S-K-L-K-K-T-D-T-E-V-K-N-T-L-P-T-K-E-T-I-D-Q-E-K-K-A-E-S-S"} +{"text": "### FUNCTION NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone ### SEQUENCE -M-R-P-R-A-N-V-C-V-G-W-A-A-C-I-L-L-V-V-C-L-C-V-L-A-E-G-Y-P-T-K-P-E-N-P-G-E-D-A-P-V-E-E-L-A-K-Y-Y-S-A-L-R-H-Y-I-N-L-I-T-R-Q-R-Y-G-K-R-S-N-T-D-V-L-T-P-D-L-L-F-G-E-A-E-I-R-L-Q-S-R-Y-D-D-P-L-M-G"} +{"text": "### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-D-C-A-K-T-G-T-C-N-C-G-A-T-C-K-C-T-N-C-Q-C-T-T-C-K-K-S-C-C-S-C-C-P-S-G-C-S-K-C-A-S-G-C-V-C-K-G-N-S-C-G-S-S-C-C-Q"} +{"text": "### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-C-V-S-R-L-V-L-L-F-G-L-L-L-C-V-G-A-Q-L-S-N-A-Q-H-W-S-H-G-W-Y-P-G-G-K-R-E-L-D-S-F-G-T-S-E-I-S-E-E-I-K-L-C-E-A-G-E-C-S-Y-L-R-P-Q-R-R-S-V-L-R-N-I-I-L-D-A-L-A-R-E-L-Q-K-R-K"} +{"text": "### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-E-A-N-S-R-V-M-V-R-V-L-L-L-A-L-V-V-Q-V-T-L-S-Q-H-W-S-Y-G-W-L-P-G-G-K-R-S-V-G-E-L-E-A-T-I-R-M-M-G-T-G-E-V-V-S-L-P-E-E-A-S-A-Q-T-Q-E-R-L-R-P-Y-N-V-I-N-D-D-S-S-H-F-D-R-K-K-R-S-P-N-K"} +{"text": "### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-A-A-Q-T-F-A-L-R-L-L-L-V-G-T-L-L-G-T-L-L-G-Q-G-C-C-Q-H-W-S-Y-G-L-S-P-G-G-K-R-E-L-D-G-L-S-E-T-L-G-N-Q-I-V-G-S-F-P-H-V-A-T-P-C-R-V-L-G-C-A-E-E-S-P-F-P-K-I-Y-R-M-K-G-F-L-D-A-V-T-D-R-E-N-G-N-R-T-Y-K-K"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-P-T-K-K-G-E-K-K-K-G-R-S-A-I-N-E-V-V-T-R-E-Y-T-I-N-V-H-K-R-I-H-G-V-G-F-K-K-R-A-P-R-A-I-K-E-I-R-K-F-A-V-K-E-M-G-T-P-D-V-R-I-D-T-R-L-N-K-A-V-W-S-K-G-V-R-N-V-P-Y-R-I-R-V-R-L-S-R-K-R-N-E-D-E-D-S-P-N-K-L-Y-T-L-V-T-Y-V-P-V-T-T-C-K-G-L-Q-T-V-N-V-D-E-N"} +{"text": "### FUNCTION TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation TFIIA in a complex with TBP mediates transcriptional activity ### SEQUENCE -M-A-Y-Q-L-Y-R-N-T-T-L-G-N-S-L-Q-E-S-L-D-E-L-I-Q-T-Q-Q-I-T-P-Q-L-A-L-Q-V-L-L-Q-F-D-K-A-I-N-T-A-L-A-S-R-V-R-N-R-V-N-F-R-G-S-L-N-T-Y-R-F-C-D-N-V-W-T-F-V-L-N-D-V-E-F-R-E-V-T-D-L-V-K-V-D-K-V-K-I-V-A-C-D-G-K-S-E-S-T-Q-N-K-S-D-K"} +{"text": "### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-K-I-A-L-V-L-L-S-L-L-A-L-T-L-A-E-S-N-I-S-P-P-V-V-K-V-Y-T-A-E-P-V-D-F-G-K-T-N-E-V-I-C-Y-V-Y-N-Y-H-P-P-R-L-E-M-R-L-E-K-N-G-V-E-I-P-D-C-K-Q-T-D-P-S-F-Q-H-N-W-K-Y-Y-T-T-K-S-T-H-V-H-I-D-K-G-D-K-V-E-C-V-V-S-H-N-G-N-P-S-K-K-Y-R-L-D-I-F"} +{"text": "### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-S-R-H-V-T-V-V-L-L-L-A-V-V-L-L-L-S-S-H-M-S-H-G-Q-H-W-S-Y-G-L-W-P-G-G-K-R-E-V-E-G-L-Q-E-S-Y-S-E-V-P-N-E-V-S-F-T-D-P-Q-H-F-E-R-S-I-P-Q-N-R-I-S-L-V-R-E-A-L-M-N-W-L-E-G-E-N-T-R-K-K-I"} +{"text": "### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-E-C-S-K-T-G-T-C-N-C-G-G-S-C-T-C-T-N-C-S-C-T-T-C-K-K-S-C-C-S-C-C-P-S-G-C-T-K-C-A-S-G-C-V-C-K-G-K-T-C-D-T-S-C-C-Q"} +{"text": "### FUNCTION Involved in the viral transport within, and between cells ### SEQUENCE -M-D-P-Q-N-S-F-L-L-Q-P-R-V-P-T-A-A-P-T-S-G-G-V-S-W-S-R-V-G-E-V-A-I-L-S-F-V-G-L-I-C-F-Y-L-L-Y-L-W-V-L-R-D-L-I-L-V-L-K-A-R-Q-G-R-S-T-E-E-L-I-F-G-I-Q-A-V-D-R-S-N-P-I-P-N-T-Q-A-P-P-S-Q-G-N-P-G-P-F-V-P-G-T-G"} +{"text": "### FUNCTION Plays a central role in virus morphogenesis and assembly Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport Also plays a role in the induction of apoptosis ### SEQUENCE -M-F-N-L-F-L-I-D-T-V-W-Y-V-G-Q-I-I-F-I-V-A-V-C-L-M-V-T-I-I-V-V-A-F-L-A-S-I-K-L-C-I-Q-L-C-G-L-C-N-T-L-L-L-S-P-S-I-Y-V-Y-N-R-S-K-Q-L-Y-K-Y-Y-N-E-E-V-R-P-P-P-L-E-V-D-D-I-I-I-Q-T-L"} +{"text": "### FUNCTION Binds double-strand RNA with high affinity Suppresses the host RNA silencing-based antiviral response ### SEQUENCE -M-T-N-M-S-C-A-Y-E-L-I-K-S-L-P-A-K-L-E-Q-L-A-Q-E-T-Q-A-T-I-Q-T-L-M-I-A-D-P-N-V-N-K-D-L-R-A-F-C-E-F-L-T-V-Q-H-Q-R-A-Y-R-A-T-N-S-L-L-I-K-P-R-V-A-A-A-L-R-G-E-E-L-D-L-G-E-A-D-V-A-A-R-V-R-Q-L-K-Q-Q-L-A-E-L-E-M-E-I-K-P-G-H-Q-Q-V-A-Q-V-S-G-R-R-K-A-A-A-A-A-P-V-A-Q-L-G-R-V-G-V-V-N-E"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 21 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-A-E-N-R-G-E-R-R-A-A-V-E-N-R-Y-D-A-W-D-H-E-Q-A-M-K-A-A-V-R-K-F-I-S-Y-D-Q-F-S-A-Q-L-R-N-W-R-E-A-R-L-N-I-I-E-H-A-T-S-V-L-S-Q-V-S-N-L-G-R-T-H-F-Y-S-R-T-E-R-F-G-G-S-S-L-V-G-D-K-L-Y-V-C-L-N-E-T-R-M-K-T-A-L-N-N-I-I-V-A-L-Q-T-V-N-G-E-G-R-A-R-R-L-G-P-R-E-A-S-A-N-T-G-G-E-D-S-A-L-N-V-A-H-Q-L-A-E-V-D-D-L-L-T-D-E-S-F-L-R-E-A-V-F-T-Q-D-K-Y-E-L-V-N-G-L-R-W-A-G-A"} +{"text": "### FUNCTION May act as transcriptional regulator Induces apoptosis in infected cells Element of infectious replication cycle ### SEQUENCE -M-N-A-H-Q-E-D-T-P-P-G-P-S-T-V-F-R-P-P-T-S-S-R-P-L-E-T-P-H-C-R-E-I-R-I-G-I-A-G-I-T-V-T-L-S-L-C-G-C-A-N-A-R-V-P-T-L-R-S-A-T-A-D-N-S-E-N-T-G-F-K-N-V-P-D-L-R-T-D-Q-P-K-P-P-S-K-K-R-S-C-D-P-S-E-Y-R-V-S-E-L-K-E-S-L-I-T-T-T-P-S-R-P-R-T-A-R-R-C-I-R-L"} +{"text": "### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-D-A-L-F-V-F-I-I-I-L-A-T-A-V-I-C-L-F-L-F-Q-A-Y-T-I-Y-D-N-Y-H-N-I-I-E-F-N-E-K-Y-G-G-L-E-Y-S-R-S-P-G-G-L-Y-I-D-K-R-V-F-D-P-N-D-S-E-T-D-P-K-A-K-W-R-C-V-N-Y-N-N-N-Q-Y-A-S-A-S-K-F-G-Y-L-A-T-S-S-R-N-P-V-L-F-T-N-L-E-D-C-V-Y-Y-N-Y-T-R-G-E-I-G-T-I-W-N-P-C-A-E-Y-G-E-G-S-A-E-C-S-T-L-K-S-H-L"} +{"text": "### FUNCTION Nuclease that specifically cleaves and resolves four-way DNA Holliday junctions into linear duplex products ### SEQUENCE -M-I-I-C-S-V-D-I-G-I-K-N-P-A-Y-A-I-F-N-Y-D-N-T-S-N-T-I-K-L-I-A-I-E-K-S-D-W-T-K-N-W-E-R-S-V-A-R-D-L-T-R-Y-N-P-D-V-V-I-L-E-K-Q-G-F-K-S-P-N-S-K-I-I-Y-F-I-K-G-F-F-Y-N-S-N-T-K-V-I-V-R-N-P-T-F-K-G-G-S-Y-R-N-R-K-K-Q-S-I-D-V-F-I-Q-K-I-S-E-Y-T-D-Y-K-N-D-I-L-N-K-Y-T-K-L-D-D-I-A-D-S-F-N-L-G-L-S-Y-M-E-S-L-L-K-K-C-K-I-S-K-D"} +{"text": "### FUNCTION Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry ### SEQUENCE -M-F-V-L-F-L-I-V-C-Y-F-I-L-I-F-N-I-I-V-P-K-I-A-D-K-L-R-L-E-H-E-A-F-T-K-Y-R-Q-I-Y-G-N-K-F-R-C-I-G-D-N-L-I-N-Y-S-F-T-P-F-G-V-K-A-N-Y-L-V-N-K-N-T-K-M-P-A-I-C-N-D-I-K-N-I-N-S-L-I-A-V-T-C-D-D-A-S-K-F-I-K-H-R-N-I-C-E-R-A-Y-T-E-L-F-L"} +{"text": "### FUNCTION Late protein which is a part of a large complex required for early virion morphogenesis This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions A15 is required for the stability and kinase activity of F10 ### SEQUENCE -M-Y-I-E-N-N-S-L-V-L-I-I-P-E-T-N-S-I-T-P-Q-L-F-T-I-H-D-N-K-P-I-C-V-C-S-R-Y-S-L-I-P-S-K-K-E-N-V-Q-I-S-Y-I-D-N-I-H-M-Y-F-R-S-F-K-N-L-Y-L-V-N-P-R-N-H-D-I-I-K-V-F-N-F-L-K-N-Y-K-W-G-G-N-F-Y-L-L-F-N-V"} +{"text": "### FUNCTION Envelope protein which is a major component of the mature virion ### SEQUENCE -M-D-P-L-G-F-F-R-N-R-P-S-Y-V-V-V-F-G-I-I-L-L-I-V-A-C-I-C-A-Y-I-E-L-S-K-S-G-K-P-A-D-S-A-L-R-S-I-S-I-I-S-F-I-L-A-I-L-L-L-L-G-I-I-L-F-S-G-Y-N-R-Y-C-T-G-N-V-V-D-E-S-R-Y-A-T-S-P-G-T-E-I-Q"} +{"text": "### FUNCTION Essential for the encapsidation of DNA into immature virions ### SEQUENCE -M-G-I-I-D-T-F-V-I-T-A-V-T-V-I-I-F-C-L-L-I-Y-A-A-Y-K-R-Y-K-C-I-P-S-P-D-D-R-D-K-V-L-K-S-T-L-N-D-D-T-L-F-N-Q-T-L-T-P-D-Q-V-K-A-L-H-R-L-V-T-S-S-I"} +{"text": "### FUNCTION Envelope protein Required for an early step in virion morphogenesis ### SEQUENCE -M-S-C-Y-S-S-I-L-N-S-I-S-T-L-A-F-L-Q-V-A-S-N-V-I-E-L-V-R-H-C-I-M-H-F-C-E-T-R-I-R-C-N-T-L-A-F-V-I-L-K-I-L-I-T-M-V-I-Y-F-M-I-G-L-G-L-F-Y-L-A-K-N-G-T-E-A-E"} +{"text": "### FUNCTION Contributes to the formation of crescents and immature virions ### SEQUENCE -M-D-H-K-S-R-M-L-L-D-T-I-F-K-D-M-L-N-T-K-D-V-Y-A-L-I-K-Y-I-F-K-K-D-P-V-E-T-I-F-S-K-K-D-D-D-I-F-I-D-F-V-Y-N-D-N-V-L-A-S-D-Y-L-G-M-K-T-T-K-V-E-D-C-C-S-C-R-K-V-V-A-V-E-Y-M-N-T-S-I-I-D-N-D-L-E-G-Y-I-K-Q-S-D-K-L-K-R-F-I-K-L-Y-N-K-N-N-A-I-K-K-A-R-N-I-K-S-R-Q-K-M-L-K-D-A-G-I-D-D-I-G-Y-E-F-I-K-D-A-I-G-L-I-S-R-K"} +{"text": "### FUNCTION Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates Responsible for the transcription of early, intermediate and late genes DNA-dependent RNA polymerase associates with the early transcription factor ### SEQUENCE -M-V-F-P-L-V-C-S-T-C-G-R-D-L-S-E-A-R-Y-R-L-L-V-E-Q-M-E-L-K-K-V-V-I-T-Y-S-R-K-C-C-R-L-K-L-S-T-Q-I-E-P-Y-R-N-L-T-V-Q-P-S-L-D-I-N"} +{"text": "### FUNCTION Plays an essential role in virion assembly and morphogenesis Also plays a role in the inhibition of host immune response by dysregulating mTOR Sequesters host RICTOR and RPTOR, thereby disrupting mTORC1 and mTORC2 crosstalk In turn, blocks the host antiviral response in part through mTOR-dependent degradation of cGAS, the primary poxvirus sensor ### SEQUENCE -M-E-E-S-A-G-T-P-F-H-D-P-K-Y-F-V-S-P-F-I-L-N-T-D-E-G-R-Y-L-V-L-K-A-I-K-L-C-N-V-R-T-I-D-C-M-K-Q-E-T-S-C-V-L-K-V-D-K-P-Q-S-P-C-P-I-S-S-S-D-S-A-P-K-C-Y-M-Q-Q-T-S-P-Q-Q-Q-R-Q-A-P-Q-L-R-F-I-N-T-G-A-L-S-N-L-F-A-N-T-T-D-K-A-A-R-V-I-N-Q"} +{"text": "### FUNCTION FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation ### SEQUENCE -M-D-P-R-Y-W-G-S-S-F-W-I-V-I-F-I-I-I-T-K-F-K-H-D-I-E-T-C-K-R-H-L-Y-N-I-C-K-A-L-P-C-A-E-C-K-D-H-A-L-Q-A-I-Q-K-N-N-I-M-S-S-N-D-I-N-Y-I-Y-F-F-F-I-S-L-Y-N-N-L-V-F-N-P-E-R-C-I-D-I-K-K-V-K-K-L-I"} +{"text": "### FUNCTION Plays a role in the inhibition of host apoptosis by sequestering and inactivating multiple proapoptotic BCL-2 proteins, including BAK1 and BAX ### SEQUENCE -M-A-S-S-N-M-K-D-E-T-Y-Y-I-A-L-N-M-I-Q-N-Y-I-I-E-Y-N-T-N-K-P-R-K-S-F-V-I-D-S-I-S-Y-D-V-L-K-A-A-C-K-S-V-I-K-T-N-Y-N-E-F-D-I-I-I-S-R-N-I-D-F-N-V-I-V-T-Q-V-L-E-D-K-I-N-W-G-R-I-I-T-I-I-A-F-C-A-Y-Y-S-K-K-V-K-Q-D-T-S-P-Q-Y-Y-D-G-I-I-S-E-A-I-T-D-A-I-L-S-K-Y-R-S-W-F-I-D-Q-D-Y-W-N-G-I-R-I-Y-K-N-Y-S-Y-I-F-N-T-A-S-Y-C-I-F-T-A-S-L-I-I-A-S-L-A-V-F-K-I-C-S-F-Y-M"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-E-E-V-T-V-Y-K-I-S-D-R-A-K-L-P-Y-K-Q-T-S-Y-S-A-G-Y-D-L-Y-S-A-Y-D-Y-V-I-E-P-M-N-K-E-L-I-K-T-D-I-I-L-K-I-P-N-G-Y-Y-G-R-I-A-P-R-S-G-L-A-Y-N-Y-F-I-D-V-G-A-G-V-I-D-S-D-Y-R-G-N-V-G-V-L-L-F-N-F-G-S-T-Q-F-N-V-C-K-G-D-R-I-A-Q-I-I-F-E-K-I-A-Y-P-K-I-I-E-V-T-T-L-E-E-I-N-I-T-D-R-G-N-S-G-F-G-S-T-G-L-K"} +{"text": "### FUNCTION Contributes to the formation of crescents and immature virions ### SEQUENCE -M-E-M-D-K-R-M-K-S-L-A-M-T-A-F-F-G-E-L-N-T-L-D-I-M-A-L-I-M-S-I-F-K-R-H-P-N-N-T-I-F-S-V-D-K-D-G-Q-F-I-I-D-F-E-Y-D-N-Y-K-A-S-Q-Y-L-D-L-T-L-T-P-I-S-G-D-E-C-K-T-H-A-S-S-I-A-E-Q-L-A-C-V-D-I-I-K-E-D-I-S-E-Y-I-K-T-T-P-R-L-K-R-F-I-K-K-Y-R-N-R-S-D-T-R-I-S-R-D-T-E-K-L-K-I-A-L-A-K-G-I-D-Y-E-Y-I-K-D-A-C"} +{"text": "### FUNCTION Plays a major role in assembly and budding of virion Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form Inhibits viral transcription and stimulates replication ### SEQUENCE -M-A-T-E-V-S-T-R-F-I-F-I-K-I-D-A-L-S-T-L-H-F-I-D-E-G-G-A-L-S-M-N-G-D-S-I-E-F-L-I-G-K-S-S-L-D-K-G-L-L-K-R-A-T-K-L-F-T-W-L-F-S-P-E-I-A-K-Q-H-L-S-I-T-R-S-T-E-S-N-V-Y-M-T-D-A-T-R-Y-K-Y-I-F-P-E-Y-L-L-V-R-Y-V-G-T-K-F-P-D-M-K-I-V-A-D-A-T-F-K-R-R-N-P-K-G-D-V-I-G-M-L-D-L-S-F-K-E-V-R-V-K-E-V-S-E-T-K-A-I-E-L-R-D-S-N-P-G-Y-L-L-S-T-T-Y-R-E-S-E-S-L-P-V-V-S-K-P"} +{"text": "### FUNCTION May be involved in ER/Golgi transport and vesicular traffic Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis ### SEQUENCE -M-S-E-V-R-L-P-P-L-R-A-L-D-D-F-V-L-G-S-A-R-L-A-A-P-D-P-G-D-P-Q-R-W-C-H-R-V-I-N-N-L-L-Y-Y-Q-T-N-Y-L-L-C-F-G-I-S-L-A-L-A-G-Y-I-R-P-L-H-T-L-L-S-A-L-V-V-V-V-A-L-G-V-L-V-W-A-A-E-T-R-A-A-V-R-R-C-R-R-S-H-P-A-A-C-L-A-A-V-L-A-I-S-L-F-I-L-W-A-V-G-G-A-F-T-F-L-L-S-I-T-A-P-V-F-L-I-L-L-H-A-S-L-R-L-R-N-L-K-N-K-I-E-N-K-I-E-S-I-G-L-K-R-T-P-M-G-L-L-L-E-A-L-G-Q-E-Q-E-A-G-S"} +{"text": "### FUNCTION Enhances production of pro-inflammatory cytokines induced by TNF, IL1B, and TLR ligands Has a role in TNF activation of both the NF-kappaB and MAPK pathways ### SEQUENCE -M-A-S-L-W-C-G-N-L-L-R-L-G-S-G-L-S-M-S-C-L-A-L-S-V-L-L-L-A-Q-L-T-G-A-A-K-N-F-E-D-V-R-C-K-C-I-C-P-P-Y-K-E-N-P-G-H-I-Y-N-K-N-I-S-Q-K-D-C-D-C-L-H-V-V-E-P-M-P-V-R-G-P-D-V-E-A-Y-C-L-R-C-E-C-K-Y-E-E-R-S-S-V-T-I-K-V-T-I-I-I-Y-L-S-I-L-G-L-L-L-L-Y-M-V-Y-L-T-L-V-E-P-I-L-K-R-R-L-F-G-H-S-Q-L-L-Q-S-D-D-D-V-G-D-H-Q-P-F-A-N-A-H-D-V-L-A-R-S-R-S-R-A-N-V-L-N-K-V-E-Y-A-Q-Q-R-W-K-L-Q-V-Q-E-Q-R-K-S-V-F-D-R-H-V-V-L-S"} +{"text": "### FUNCTION Essential factor for the assembly of mitochondrial NADHubiquinone oxidoreductase complex ### SEQUENCE -M-A-T-A-L-G-F-R-C-L-F-R-T-R-P-A-P-L-C-R-H-V-D-R-L-W-R-N-P-R-R-G-H-R-L-S-P-A-D-D-E-L-Y-Q-R-T-R-I-S-L-L-Q-S-E-F-P-Q-A-V-Y-I-D-S-Y-S-S-R-G-F-T-I-C-G-N-R-V-F-G-P-C-V-L-L-P-Q-T-V-V-Q-W-N-V-G-S-H-Q-D-I-T-E-E-S-F-S-L-F-W-M-L-E-P-R-I-E-I-V-V-V-G-T-G-N-K-T-E-R-L-H-P-Q-V-L-Q-A-M-R-Q-R-G-I-A-V-E-V-Q-D-T-P-N-A-C-A-T-F-N-F-L-C-H-E-G-R-V-T-G-A-A-L-I-P-P-P-G-E-T-A-L-A-S-L-G-Q-A-S-E"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-T-R-C-D-D-R-P-S-A-S-Q-I-S-I-T-H-V-T-Q-G-S-C-V-A-S-S-S-P-N-E-V-Y-A-T-I-L-G-S-C-I-C-T-C-M-C-D-P-V-A-G-V-G-G-M-N-H-F-L-L-P-S-A-D-V-E-D-A-Q-H-L-R-Y-G-S-H-A-M-E-L-L-I-N-A-L-L-K-L-G-A-A-R-Q-R-I-E-A-K-I-F-G-G-A-M-M-T-P-Q-L-G-A-I-G-Q-A-N-A-A-F-A-R-R-Y-L-R-D-E-G-I-R-C-T-A-H-S-L-G-G-N-R-A-R-R-I-R-F-W-P-K-T-G-R-V-Q-Q-M-F-L-G-S-E-D-V-V-P-N-E-Q-P-Q-F-R-L-Q-G-G-A-G-D-V-T-F-F-D-R-H-N-N-A-E-M-P-D-P-I-K-E-P-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-T-K-N-V-R-T-L-Q-G-K-V-V-S-D-K-M-D-K-T-V-T-V-L-V-E-R-K-V-K-H-P-L-Y-G-K-I-I-R-L-S-T-K-I-H-A-H-D-E-N-N-Q-Y-G-I-G-D-V-V-V-I-S-E-S-R-P-L-S-K-T-K-S-W-V-V-S-E-L-V-E-K-A-R-S-I"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-S-A-K-P-H-E-V-K-R-E-W-F-V-I-D-A-Q-D-K-V-L-G-R-V-A-A-E-V-A-S-R-L-R-G-K-H-K-P-E-Y-T-P-H-V-D-T-G-D-Y-I-I-V-I-N-A-D-K-L-R-V-T-G-A-K-F-E-D-K-K-Y-F-R-H-S-G-F-P-G-G-I-Y-E-R-T-F-R-E-M-Q-E-Q-F-P-G-R-A-L-E-Q-A-V-K-G-M-L-P-K-G-P-L-G-Y-A-M-I-K-K-L-K-V-Y-A-G-A-E-H-A-H-A-A-Q-Q-P-K-V-L-E-L-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-H-T-T-R-L-R-R-A-R-K-T-R-A-R-I-A-D-L-K-M-V-R-L-C-V-F-R-S-N-N-H-I-Y-A-Q-V-I-S-A-E-G-D-K-V-L-A-Q-A-S-T-L-E-A-E-V-R-G-S-L-K-S-G-S-N-V-E-A-A-A-I-V-G-K-R-I-A-E-K-A-K-A-A-G-V-E-K-V-A-F-D-R-S-G-F-Q-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-N-G-L-S-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-V-E-Q-K-A-Q-I-V-K-D-F-Q-R-K-E-G-D-T-G-S-S-E-V-Q-V-A-L-L-T-F-R-I-N-D-L-T-P-H-F-K-A-N-P-K-D-H-H-S-R-R-G-L-L-K-M-V-S-Q-R-R-R-L-L-A-Y-L-R-R-T-Q-P-D-T-Y-R-A-L-I-T-R-L-G-L-R-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-I-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-S-V-G-D-I-I-K-V-A-V-K-D-A-A-P-R-G-R-V-K-K-G-D-V-Y-N-A-V-V-V-R-T-A-K-G-V-R-R-P-D-G-A-L-I-K-F-D-N-N-A-A-V-L-L-N-N-K-L-E-P-L-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-R-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-E-Q-T-Q-Q-Q-N-S-E-E-A-V-E-N-V-E-A-V-E-T-V-E-T-V-G-N-A-D-G-V-Q-E-Q-A-A-A-E-P-A-Y-E-D-L-Q-A-R-I-A-E-L-E-A-Q-L-K-D-E-Q-L-R-A-L-A-N-E-Q-N-L-R-R-R-H-Q-Q-E-I-A-D-T-H-K-F-A-G-Q-K-F-A-V-E-M-L-P-V-K-D-Y-L-E-M-A-L-L-D-Q-S-G-N-F-D-A-L-K-M-G-V-Q-M-T-L-N-E-L-Q-K-A-F-D-A-T-Q-I-K-E-I-N-P-K-A-G-D-K-L-D-P-N-I-H-Q-A-M-Q-A-V-A-S-E-Q-E-P-N-T-V-V-G-V-M-K-K-G-Y-T-L-S-D-R-V-L-R-P-A-M-V-T-V-A-Q-K-E-A"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-T-R-L-K-Y-R-K-Q-Q-K-G-R-N-T-G-I-A-T-R-G-N-K-V-S-F-G-E-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-H-I-K-R-G-G-R-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-I-Q-V-R-M-G-G-G-K-G-N-V-E-Y-Y-I-A-E-I-K-P-G-K-V-L-Y-E-M-D-G-V-P-E-E-L-A-R-E-A-F-E-L-A-A-A-K-L-P-I-P-T-T-F-V-V-R-Q-V-G-Q"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-S-E-L-I-Q-A-I-A-D-E-A-E-L-S-K-R-A-A-A-E-F-V-N-A-F-V-S-V-V-T-Q-E-L-K-D-G-N-D-V-T-L-V-G-F-G-T-F-H-A-A-Q-S-A-E-R-Q-G-R-N-P-K-T-G-E-P-L-T-I-A-A-R-K-T-P-K-F-R-S-G-K-A-L-K-D-A-V-N-G"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-R-V-N-A-Q-H-K-N-A-R-I-S-A-Q-K-A-R-L-V-A-D-L-I-R-G-K-D-V-A-Q-A-L-N-I-L-A-F-S-P-K-K-G-A-E-L-I-K-K-V-L-E-S-A-I-A-N-A-E-H-N-N-G-A-D-I-D-E-L-K-V-V-T-I-F-V-D-K-G-P-S-L-K-R-F-Q-A-R-A-K-G-R-G-N-R-I-E-K-Q-T-C-H-I-N-V-T-V-G-N"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-V-K-T-G-G-K-Q-Y-K-V-S-V-G-E-K-L-K-V-E-Q-I-P-A-E-L-D-S-Q-I-E-L-T-E-V-L-M-I-A-D-G-E-S-V-K-V-G-A-P-F-I-E-G-A-K-V-T-A-K-V-V-A-H-G-R-G-E-K-V-R-I-F-K-M-R-R-R-K-H-Y-Q-K-R-Q-G-H-R-Q-N-F-T-Q-I-E-I-V-A-I-A"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-G-K-M-I-I-D-L-Q-I-A-S-A-D-E-S-G-L-P-T-A-A-Q-I-E-Q-W-A-T-A-A-V-Q-P-Q-S-G-E-V-E-M-T-V-R-I-V-D-E-T-E-S-H-A-L-N-F-N-Y-R-G-K-D-H-P-T-N-V-L-S-F-P-F-E-C-P-D-E-V-E-L-P-L-L-G-D-L-V-I-C-R-Q-V-V-E-R-E-A-Q-E-Q-E-K-P-L-I-A-H-W-A-H-M-V-V-H-G-S-L-H-L-L-G-Y-D-H-I-E-D-D-E-A-E-E-M-E-S-L-E-T-Q-I-M-M-G-L-G-F-V-D-P-Y-L-S-E-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-K-K-N-A-P-K-S-F-E-E-A-L-S-R-L-E-S-L-T-Q-A-M-Q-G-E-M-P-L-E-D-A-L-A-A-Y-Q-E-G-N-E-L-V-I-Y-C-Q-T-K-L-A-Q-V-E-Q-K-L-Q-V-L-D-A-D-G-L-K-E-L-N-L-E-S-D-E"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-S-R-L-T-G-K-L-V-E-K-N-P-P-Q-I-V-I-D-V-N-G-V-G-Y-E-A-D-V-S-M-Q-T-F-Y-N-L-P-P-V-G-E-S-V-Q-L-F-T-Q-L-I-I-R-E-D-A-H-L-L-F-G-F-A-T-A-E-E-R-K-T-F-R-Q-L-I-K-V-G-G-I-G-A-K-T-A-L-G-I-L-S-A-M-T-A-D-E-L-A-Q-A-V-A-E-E-D-V-K-R-L-S-S-A-P-G-I-G-K-K-T-A-E-R-M-V-L-E-L-R-G-K-L-V-A-H-A-V-T-D-G-L-F-A-A-A-P-A-A-D-E-T-E-D-I-V-G-T-L-L-A-L-G-Y-S-E-R-E-A-K-A-A-V-K-G-V-P-E-G-T-D-V-G-E-G-V-R-L-A-L-K-N-L-L-K"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-A-E-S-R-Q-T-R-L-Q-V-K-C-P-T-C-Q-T-A-V-V-W-E-P-E-N-A-F-R-P-F-C-S-Q-R-C-K-L-I-D-L-G-G-W-A-D-G-K-Y-T-V-S-G-Q-T-E-S-L-P-E-I-S-E-P-D-M-A-Y-R"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-L-D-R-E-G-Y-R-P-N-V-G-I-I-L-I-N-E-R-N-E-V-F-W-G-K-R-V-R-E-H-S-W-Q-F-P-Q-G-G-I-K-P-G-E-S-P-E-T-A-M-Y-R-E-L-Y-E-E-V-G-L-L-P-Q-H-V-K-I-I-G-R-T-R-D-W-L-R-Y-D-V-P-N-N-W-V-R-R-E-W-R-G-S-Y-R-G-Q-K-Q-I-W-Y-L-L-R-L-T-G-R-D-C-D-V-N-L-R-A-T-R-H-P-E-F-D-G-W-R-W-H-Q-Y-W-A-P-V-D-E-V-I-D-F-K-R-D-V-Y-L-G-A-L-K-E-L-S-S-R-F-L-R-G-M-E-S-Y-E-D-F-A-A-R-Q-S-S-D-N-R"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-T-P-L-F-R-K-A-V-W-L-L-F-A-V-S-V-C-A-F-A-G-S-L-A-A-Q-Y-V-L-G-M-E-P-C-V-L-C-I-S-Q-R-L-C-V-L-A-T-A-L-C-A-A-I-V-L-M-C-R-P-R-R-K-A-G-G-L-F-G-A-V-F-I-S-I-P-A-V-T-G-I-S-V-A-A-Y-Q-L-W-L-Q-S-L-P-P-G-T-A-P-S-C-G-A-P-W-T-F-R-L-K-G-W-P-L-F-D-W-F-E-P-V-V-R-G-F-G-N-C-A-E-P-D-Y-L-L-G-V-A-L-P-V-W-S-V-A-Y-F-L-A-V-A-L-T-V-W-W-A-W-A-R-A-K"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-K-P-Q-K-S-L-R-A-R-A-M-D-I-L-S-R-Q-E-L-S-R-I-G-L-K-R-K-L-A-P-H-A-E-S-E-E-E-L-E-N-V-L-N-E-F-A-E-R-N-W-Q-S-D-L-R-Y-A-E-A-Y-I-R-S-K-S-R-K-H-G-S-L-R-L-K-Q-A-L-A-Q-Q-G-I-D-E-E-T-S-R-N-L-L-P-D-R-S-S-E-K-L-A-A-I-A-V-L-R-K-K-F-K-H-P-A-A-D-L-K-E-K-Q-K-Q-A-R-F-L-A-Y-R-G-F-D-A-D-T-V-Q-T-A-L-K-H-A-W-D-E-N-W-E-D-G-C"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-A-G-L-G-G-L-M-K-Q-A-Q-Q-M-Q-E-N-M-K-K-A-Q-A-K-L-A-E-T-E-I-E-G-E-A-G-N-G-L-V-K-I-T-M-T-C-A-H-E-V-R-K-I-D-I-S-P-D-L-I-Q-E-A-A-D-D-K-E-M-L-E-D-L-I-L-A-A-L-K-S-A-R-D-K-A-E-E-T-A-N-K-T-M-G-A-F-T-Q-G-L-P-P-G-V-G-D-F-F-R"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-Q-K-I-P-L-T-V-R-G-A-E-L-L-K-Q-E-L-Q-Q-L-K-S-V-A-R-P-E-V-I-E-A-I-A-E-A-R-S-H-G-D-L-S-E-N-A-E-Y-E-A-A-K-E-R-Q-G-F-I-E-G-R-I-S-E-L-E-H-K-L-S-V-A-H-I-I-N-P-T-E-I-H-A-E-G-K-I-V-F-G-T-T-V-T-L-E-D-L-E-T-E-E-H-V-T-Y-Q-I-V-G-E-D-E-A-D-I-K-Q-G-K-I-Y-V-G-S-P-I-A-R-A-L-I-G-K-E-E-G-D-T-A-E-V-Q-A-P-G-G-V-R-E-Y-D-I-I-E-V-R-Y-I"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-S-Q-Y-F-T-L-F-R-I-E-P-A-F-D-I-D-T-E-N-L-E-Q-T-Y-R-A-L-A-A-R-F-H-P-D-K-F-A-S-A-S-A-F-E-Q-K-Q-A-V-M-M-S-S-T-I-N-D-A-Y-R-T-L-K-N-P-I-D-R-A-A-Y-L-L-K-T-S-G-I-D-A-D-A-P-E-H-T-S-F-A-S-E-F-L-M-Q-Q-M-E-W-R-E-T-L-M-E-A-R-A-G-K-D-L-E-S-L-K-N-L-D-N-E-I-R-D-E-Q-E-K-L-F-C-G-L-K-Q-S-F-A-R-Q-D-Y-D-T-A-A-Q-Q-V-R-Q-G-R-F-L-D-K-L-R-N-E-I-S-S-A-L"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-R-K-P-Q-R-G-Y-A-R-Q-D-R-V-K-E-Q-I-M-R-E-L-A-E-L-V-R-T-G-L-K-D-P-R-A-G-F-I-T-V-N-E-V-E-V-T-R-D-Y-S-H-A-T-V-F-Y-T-V-L-N-Q-D-A-R-E-I-T-E-E-V-L-E-H-A-R-G-H-L-R-S-E-L-A-K-R-I-K-L-F-K-I-P-E-L-H-F-K-Y-D-E-S-L-E-R-G-L-N-L-S-A-L-I-D-Q-V-A-A-E-K-P-V-E-D"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-A-L-T-L-A-D-V-D-K-I-A-R-L-S-R-L-H-L-T-A-A-E-K-E-K-S-L-Q-E-L-N-D-I-F-A-M-V-E-Q-M-Q-N-I-N-T-D-G-I-E-P-M-A-H-P-H-E-A-A-L-R-L-R-E-D-E-V-T-E-T-D-R-A-A-E-Y-Q-A-V-A-P-E-V-R-N-R-L-Y-I-V-P-Q-V-I-E-E"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-H-K-I-P-K-G-T-A-L-A-F-D-F-G-E-A-R-I-G-V-A-Q-G-D-A-E-L-G-L-S-H-P-L-A-T-V-T-G-G-S-N-D-E-K-F-A-A-I-A-K-L-V-Q-E-W-Q-P-R-Y-F-V-V-G-L-P-V-H-T-D-G-T-K-H-E-M-T-H-L-S-R-K-F-G-R-R-L-N-G-R-F-N-L-P-V-Y-W-V-D-E-R-L-S-S-V-Y-A-E-S-L-L-S-E-A-Q-V-F-G-K-K-R-K-S-V-L-D-Q-V-A-A-Q-A-I-L-H-G-F-F-E-G-G-P-A-E-C-F-N-G-R-E-G"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-I-V-H-P-D-Q-S-E-Q-V-P-A-M-V-E-R-Y-K-T-M-I-A-E-A-N-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-I-H-K-A-H-Y-V-L-M-N-I-E-T-T-P-E-V-V-E-E-L-E-T-A-F-R-F-N-D-A-V-L-R-H-L-T-I-K-T-K-H-A-V-T-E-A-S-P-M-L-G-G-E-K-A-K-N-L-L-S-G-A-S-E-E-A-V-A-Q"} +{"text": "### FUNCTION Stimulates the DNA unwinding activity of PriA helicase, which does not seem to require single-stranded DNA-binding by PriB Activates DNA-dependent ATP hydrolysis catalyzed by PriA ### SEQUENCE -M-G-F-N-N-L-V-S-L-A-V-L-I-E-K-V-F-P-I-R-Y-T-P-A-G-I-P-V-L-D-I-I-L-K-H-E-S-W-Q-E-E-N-G-Q-Q-C-L-V-Q-L-E-I-P-A-R-I-L-G-R-Q-A-E-E-W-Q-Y-R-Q-G-V-Y-V-H-V-E-G-F-L-A-Q-K-S-R-R-S-L-M-P-M-L-R-I-Q-N-I-Q-E-Y-K-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-E-K-I-G-G-L-G-N-L-G-D-I-V-T-V-K-N-G-Y-A-R-N-F-L-I-P-A-G-K-A-K-R-A-T-E-A-N-M-K-E-F-E-A-R-R-A-E-L-E-A-K-Q-A-E-I-L-A-D-A-R-V-R-Q-E-K-L-D-G-Q-T-I-T-V-A-Q-K-A-G-V-D-G-R-L-F-G-S-V-T-N-A-D-I-A-A-A-I-V-A-A-G-I-E-A-V-K-A-N-V-R-L-P-N-G-P-L-K-A-V-G-E-Y-E-V-E-V-A-L-H-T-D-A-V-A-K-I-T-V-A-V-V-A-A-T-E"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-S-N-I-I-P-L-S-I-G-A-A-L-G-A-T-A-R-W-L-L-N-L-A-V-P-A-S-L-S-P-A-T-G-N-L-F-A-N-W-T-G-A-F-L-I-G-I-F-A-E-T-V-N-H-P-Q-W-K-L-L-L-I-T-G-F-L-G-S-L-T-T-L-S-G-F-S-L-E-T-V-T-L-L-Q-S-N-R-P-A-S-A-L-A-N-I-F-L-H-T-A-G-S-L-L-L-T-W-L-G-L-K-I-G-T-A-V-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-T-A-Q-E-L-R-A-G-N-V-F-M-V-G-N-D-P-M-V-V-Q-K-T-E-Y-I-K-G-G-R-S-S-A-K-V-S-M-K-L-K-N-L-L-T-G-A-A-S-E-T-I-Y-K-A-D-D-K-F-D-V-V-I-L-S-R-K-N-C-T-Y-S-Y-F-A-D-P-M-Y-V-F-M-D-E-E-F-N-Q-Y-E-I-E-A-D-N-I-G-D-A-L-K-F-I-V-D-G-M-E-D-Q-C-E-V-T-F-Y-E-G-N-P-I-S-V-E-L-P-T-I-I-V-R-E-V-E-Y-T-E-P-A-V-K-G-D-T-S-G-K-V-M-K-T-A-R-L-V-G-G-T-E-I-Q-V-M-S-Y-I-E-N-G-D-K-I-E-I-D-T-R-T-G-E-F-R-K-R-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-N-I-E-V-E-M-K-V-L-D-E-R-M-A-D-V-V-P-V-Y-A-T-K-G-S-A-G-L-D-L-R-A-C-L-D-E-E-V-V-L-Q-P-G-E-T-F-L-V-P-T-G-L-A-I-Y-L-A-D-P-S-Y-A-A-V-L-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-E-L-K-V-S-L-W-N-R-S-S-E-P-F-T-V-K-P-F-E-R-I-A-Q-M-V-I-V-P-I-V-Q-A-R-F-K-R-V-E-E-F-V-G-S-S-R-G-E-G-G-F-G-S-T-G-L-H"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-T-Y-E-I-Q-A-S-V-R-E-A-Q-G-T-G-A-S-R-R-L-R-R-E-G-Q-I-P-G-I-L-Y-G-E-G-Q-E-P-V-A-I-A-V-D-H-K-T-V-F-Y-A-L-E-K-E-S-F-H-T-A-L-I-K-L-S-L-N-G-E-T-K-D-V-I-V-R-D-F-Q-M-H-P-F-R-R-E-V-Q-H-I-D-F-Q-A-V-K-A-D-Q-P-V-R-I-R-V-P-L-H-I-V-N-A-E-N-S-Q-A-V-K-L-Q-G-G-R-V-S-L-L-N-T-T-V-E-V-V-A-L-P-A-N-I-P-A-F-L-D-L-D-C-A-E-V-V-A-G-D-I-L-H-L-S-D-I-K-L-P-E-G-V-E-S-V-S-L-K-R-N-E-N-L-A-V-A-T-V-T-G-K-K-R"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-N-H-P-N-T-D-H-Q-S-D-T-L-L-S-D-I-N-T-Q-P-P-K-R-Y-G-V-F-L-L-N-D-D-Y-T-T-M-E-F-V-V-E-I-L-T-E-V-F-M-L-A-Q-E-Q-A-V-A-V-M-L-L-V-H-H-E-G-K-G-L-C-G-T-Y-T-R-D-I-A-Q-T-K-Q-H-Q-V-M-E-R-A-K-T-E-G-H-P-L-K-C-I-V-E-E-V"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-N-T-I-K-M-V-V-G-L-G-N-P-G-K-E-Y-E-Q-T-R-H-N-A-G-F-W-F-L-D-E-L-A-W-K-W-K-A-S-F-K-E-E-K-K-F-F-G-E-V-A-R-A-T-L-P-D-G-D-V-W-L-L-K-P-T-T-F-M-N-R-S-G-Q-A-V-A-A-L-A-Q-F-Y-K-I-K-P-E-E-I-L-V-V-H-D-E-L-D-I-P-C-G-R-I-K-F-K-L-G-G-G-N-G-G-H-N-G-L-K-D-I-Q-A-K-L-G-T-A-D-Y-Y-R-L-R-L-G-I-G-H-P-G-D-R-N-L-V-V-G-Y-V-L-N-K-P-S-T-E-H-R-R-Q-I-D-D-A-V-A-K-S-L-Q-A-I-P-D-I-L-A-G-K-C-E-E-A-T-R-F-L-H-S-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-R-A-R-H-Q-K-I-F-A-L-A-K-G-Y-R-G-R-R-K-N-V-Y-R-V-A-K-Q-A-V-M-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-Q-L-W-I-V-R-I-N-A-G-A-R-E-N-G-L-S-Y-S-K-F-M-N-G-L-K-R-A-S-I-E-I-D-R-K-V-L-A-D-L-A-V-F-D-K-A-A-F-A-Q-L-V-E-K-A-K-A-A-L-A-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-S-T-E-T-K-N-Y-I-T-P-A-G-W-Q-A-L-K-D-E-L-Y-Q-L-V-N-K-E-R-P-E-I-V-Q-I-V-N-W-A-A-G-N-G-D-R-S-E-N-G-D-Y-L-Y-G-K-R-R-M-R-E-I-D-R-R-I-R-F-L-T-K-R-L-E-A-A-V-V-V-D-P-E-L-R-E-A-T-D-Q-V-F-F-G-A-T-V-G-L-L-R-G-D-G-R-E-Q-T-V-K-I-V-G-I-D-E-I-D-T-A-Q-N-K-I-S-W-I-S-P-L-A-R-C-L-I-K-A-R-E-G-D-E-V-V-L-N-T-P-E-G-R-E-E-I-E-I-L-S-V-E-Y-I-K-I-D"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-T-A-R-R-R-S-R-E-L-A-V-Q-A-V-Y-Q-S-L-I-N-R-T-A-A-P-E-I-A-K-N-I-R-E-M-P-D-F-A-K-A-D-E-E-L-F-N-K-L-F-F-G-T-Q-T-N-A-A-E-Y-I-R-Q-I-R-P-L-L-D-R-D-E-K-D-L-N-P-I-E-R-A-V-L-L-T-A-C-H-E-L-S-A-M-P-E-T-P-Y-P-V-I-I-N-E-A-I-E-V-T-K-T-F-G-G-T-D-G-H-K-F-V-N-G-I-L-D-K-L-A-A-Q-I-R-P-D-E-P-K-R-R"} +{"text": "### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate forming two phosphate ions ### SEQUENCE -M-A-D-F-N-Q-I-L-T-T-G-D-V-D-G-G-I-I-N-V-V-N-E-I-P-A-G-S-N-H-K-I-E-W-N-R-K-L-A-A-F-Q-L-D-R-V-E-P-A-I-F-A-K-P-T-N-Y-G-F-I-P-Q-T-L-D-E-D-G-D-E-L-D-V-L-L-V-T-E-Q-P-L-A-T-G-V-F-L-E-A-R-V-I-G-V-M-K-F-V-D-D-G-E-V-D-D-K-I-V-C-V-P-A-D-D-R-N-N-G-N-A-Y-K-T-L-A-D-L-P-Q-Q-L-I-K-Q-I-E-F-H-F-N-H-Y-K-D-L-K-K-A-G-T-T-K-V-E-S-W-G-D-A-E-E-A-K-K-V-I-K-E-S-I-E-R-W-N-K-Q-A"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-D-T-Q-N-R-V-A-M-G-Y-I-K-G-V-F-G-I-K-G-W-L-K-I-A-A-N-T-E-Y-S-D-S-L-L-D-Y-P-E-W-H-L-V-K-D-G-K-T-I-S-V-T-L-E-A-G-K-V-V-N-S-E-L-Q-V-K-F-E-G-I-N-D-R-D-L-A-F-S-L-H-G-Y-T-I-E-I-P-R-E-A-F-A-P-T-E-E-D-E-Y-Y-W-T-D-L-V-G-M-T-V-V-N-K-D-H-T-V-L-G-K-V-S-N-L-M-E-T-G-A-N-D-V-L-M-I-D-G-E-H-G-Q-I-L-I-P-F-V-S-Q-Y-I-E-T-V-D-T-G-S-K-I-I-T-A-D-W-G-L-D-Y"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-L-I-Q-Q-L-E-Q-E-E-I-A-R-L-N-K-D-I-P-E-F-A-P-G-D-T-V-V-V-S-V-R-V-V-E-G-T-R-S-R-L-Q-A-Y-E-G-V-V-I-A-R-R-N-R-G-L-N-S-N-F-I-V-R-K-I-S-S-G-E-G-V-E-R-T-F-Q-L-Y-S-P-T-V-E-K-I-E-V-K-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-G-L-T-G-K-A-A-R-I-K-E-K-L-P-A-R-K-G"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-S-N-I-P-A-E-L-K-Y-V-A-S-H-E-W-L-R-L-E-E-D-G-I-I-T-V-G-I-T-H-H-A-Q-E-L-L-G-D-I-V-F-V-E-L-P-E-V-G-A-N-L-A-A-E-E-Q-A-G-V-V-E-S-V-K-A-A-S-D-V-Y-A-P-I-A-G-E-V-V-A-V-N-E-D-L-P-S-A-P-E-T-A-N-S-D-P-Y-G-A-G-W-F-F-K-L-K-P-A-N-V-A-D-Y-D-V-L-L-T-A-E-Q-Y-A-G-E-V-D"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-K-R-T-K-K-Y-P-F-L-T-L-Q-R-Q-R-F-H-L-N-F-E-N-A-S-S-A-A-G-I-P-A-E-R-D-F-Y-R-W-A-W-S-A-L-K-S-G-Y-R-R-A-D-I-S-L-I-L-L-D-E-E-E-A-R-A-Y-N-R-D-Y-R-G-K-D-Y-A-T-N-V-L-S-F-A-L-N-E-G-E-I-L-P-C-Q-V-S-E-K-L-Y-G-D-L-I-I-C-P-Q-V-V-L-K-E-A-A-E-Q-G-K-T-P-E-R-H-F-A-H-L-T-I-H-G-V-L-H-L-M-G-Y-D-H-I-E-D-D-E-A-E-I-M-E-A-E-E-I-R-L-M-L-A-A-G-F-P-N-P-Y-Q-E-D-G-H"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-E-E-L-Q-P-V-F-S-I-E-R-L-Y-V-K-D-L-S-L-E-V-P-H-A-P-Q-I-F-L-E-Q-G-E-P-E-V-D-M-R-V-S-T-G-S-Q-K-L-E-D-G-Y-Y-N-V-D-V-T-V-T-V-T-A-K-L-D-N-E-R-T-M-F-L-N-E-V-T-Q-S-G-I-F-R-L-E-N-I-P-E-E-D-A-D-L-L-L-G-V-A-C-P-N-I-L-F-P-Y-A-R-E-A-V-S-G-T-V-T-R-A-G-F-P-P-V-L-L-A-P-I-N-F-E-A-I-Y-Q-Q-Q-Q-E-A-E-A-A-G-A"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-Q-T-V-T-M-Y-T-G-P-F-C-P-Y-C-T-M-A-K-R-L-L-H-A-A-G-V-G-H-I-D-E-I-R-V-D-A-S-P-E-A-F-A-E-M-Q-Q-L-S-G-Q-R-S-V-P-Q-I-F-I-G-E-T-H-V-G-G-F-T-D-L-Y-R-L-Q-Q-E-G-G-L-D-G-L-L-N-P"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-F-C-T-H-P-D-T-R-V-A-D-S-R-L-M-E-E-R-N-A-V-R-R-R-R-H-C-P-N-C-G-K-R-F-G-T-L-E-T-A-E-L-K-M-P-A-V-I-G-P-D-K-K-R-S-P-F-N-A-Q-R-L-R-N-D-L-T-A-A-A-R-K-S-A-L-T-P-E-Q-I-D-E-T-V-R-L-T-E-H-R-L-Y-T-S-G-Q-R-D-I-P-S-A-A-L-A-D-M-V-L-K-E-L-L-R-Q-D-T-E-A-A-V-R-F-A-A-L-H-K-R-F-D-N-P-A-D-F-A-S-W-L-A-Q-A-V-K-T-G-G-K-A"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-Q-D-K-N-N-L-C-W-L-D-M-E-M-T-G-L-N-P-E-T-D-R-I-I-E-V-A-M-I-I-T-D-S-D-L-N-V-L-A-Q-S-E-V-Y-A-I-H-Q-S-D-E-L-L-D-N-M-D-E-W-N-T-A-T-H-G-R-T-G-L-T-Q-R-V-R-E-S-S-H-T-E-A-E-V-E-Q-K-L-L-D-F-M-S-E-W-V-P-R-R-A-T-P-M-C-G-N-S-I-H-Q-D-R-R-F-M-V-K-Y-M-P-K-L-E-N-Y-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-A-K-R-W-N-P-P-V-A-K-S-V-V-K-R-G-S-H-K-A-L-D-D-I-L-E-S-I-E-E-M-R-H-Y-R-E-H-F-L-I-S-A-P-R-A-E-A-Q"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-D-Y-R-F-G-R-Q-Y-R-L-L-K-T-D-D-F-S-S-V-F-A-F-R-N-R-R-S-R-D-L-L-Q-V-S-R-S-N-G-N-G-L-D-H-P-R-I-G-L-V-V-G-K-K-T-A-K-R-A-N-E-R-N-Y-M-K-R-V-I-R-D-W-F-R-L-N-K-N-R-L-P-P-Q-D-F-V-V-R-V-R-R-K-F-D-R-A-T-A-K-Q-A-R-A-E-L-A-Q-L-M-F-G-N-P-A-T-G-C-R-K-Q-A"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-G-L-E-L-P-L-I-L-G-T-S-S-V-F-R-R-E-Q-M-E-R-L-G-I-A-F-Q-A-A-S-P-D-F-D-E-T-P-M-L-G-E-S-A-P-Q-T-A-L-R-L-A-E-G-K-A-R-S-L-A-G-R-F-P-E-A-L-I-V-G-A-D-Q-V-A-W-C-D-G-R-Q-W-G-K-P-M-N-L-A-N-A-Q-K-M-L-M-H-L-S-G-R-E-I-E-F-Y-S-A-V-V-L-L-N-T-V-T-G-R-M-Q-R-H-I-D-K-T-V-V-V-M-R-K-L-D-E-L-H-I-L-R-Y-L-E-R-E-P-D-A-V-Y-C-S-C-A-L-K-S-E-A-L-G-A-L-L-I-E-R-I-E-S-T-D-P-N-A-L-I-G-L-P-V-F-R-L-V-D-F-L-K-N-E-G-V-D-V-L"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-I-M-Q-V-E-V-V-S-S-E-Q-K-I-Y-S-G-E-A-T-F-I-V-V-P-T-V-Q-G-E-L-G-I-Y-P-R-H-E-P-I-M-S-L-V-R-L-G-A-L-R-L-T-V-L-G-E-D-K-E-V-L-V-A-V-S-G-G-V-L-E-V-Q-P-D-K-V-T-V-L-A-D-V-A-V-R-S-A-E-M-D-Q-A-R-A-E-E-A-K-K-A-A-E-A-G-I-S-Q-A-K-D-D-K-A-L-A-E-A-H-K-A-L-A-A-A-I-A-Q-L-K-T-L-D-Y-I-R-S-H-K-K"} +{"text": "### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-V-R-R-L-I-I-G-I-S-G-A-S-G-F-Q-Y-G-V-K-A-L-E-L-L-R-A-Q-D-I-E-T-H-L-V-V-S-K-G-A-E-M-A-R-A-S-E-T-A-Y-A-R-D-E-V-Y-A-L-A-D-F-V-H-P-I-G-N-I-G-A-C-I-A-S-G-T-F-K-T-D-G-M-L-V-A-P-C-S-M-R-T-L-A-S-V-V-H-G-F-G-D-N-L-L-T-R-A-A-D-V-V-L-K-E-R-R-R-L-V-L-M-V-R-E-T-P-L-N-L-A-H-L-D-N-M-K-R-V-T-E-M-G-G-V-V-F-P-P-V-P-A-M-Y-R-K-P-Q-T-A-D-D-I-V-A-H-S-V-A-H-A-L-S-L-F-G-I-D-T-P-D-S-A-E-W-Q-G-M-A-D"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-T-I-R-P-L-H-D-R-V-V-V-K-R-L-E-A-E-E-K-T-A-S-G-I-V-L-P-G-A-A-A-E-K-P-D-M-G-E-V-I-A-V-G-A-G-K-I-G-K-D-G-A-R-R-P-L-D-V-K-V-G-D-K-I-I-F-G-K-Y-S-G-Q-T-V-K-A-D-G-E-E-L-L-V-M-R-E-E-D-I-F-G-I-V-E-K"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-K-V-D-H-T-R-M-H-A-P-A-V-R-V-A-K-T-M-T-T-P-K-G-D-T-I-T-V-F-D-L-R-F-C-V-P-N-K-E-I-L-P-E-K-G-I-H-T-L-E-H-L-F-A-G-F-M-R-D-H-L-N-G-N-G-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-T-P-S-E-Q-Q-V-A-D-A-W-L-A-S-M-Q-D-V-L-N-V-K-D-Q-S-K-I-P-E-L-N-E-Y-Q-C-G-T-Y-Q-M-H-S-L-A-E-A-Q-Q-I-A-Q-N-V-L-A-R-K-V-A-V-N-K-N-E-E-L-T-L-D-E-G-L-L-N-A"} +{"text": "### FUNCTION May nick NmeAIP sequences that contain T/G mispairs resulting from m5C-deamination If unrepaired, these mismatches can lead to C-to-T transition mutations The very short patch next to the thymidine residue that is mismatched to 2'-deoxyguanosine The incision is mismatch-dependent and strand-specific ### SEQUENCE -M-T-D-I-F-T-T-S-K-R-S-F-V-M-L-K-I-H-S-K-E-T-K-P-E-V-L-V-R-K-F-L-F-F-Q-G-F-R-Y-R-K-N-D-K-R-Y-V-G-K-P-D-I-V-L-S-K-Y-K-T-V-V-F-I-H-G-C-F-W-Y-G-H-S-C-N-K-G-H-I-P-K-S-N-T-D-F-W-L-E-K-I-T-K-N-C-E-R-D-I-K-N-E-T-E-L-E-K-I-G-F-K-V-I-V-V-W-E-C-E-L-K-N-K-A-I-C-R-E-R-L-N-R-L-V-R-E-I-K-D-A-V"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-K-N-M-G-Q-M-M-K-Q-M-Q-K-M-Q-K-Q-M-M-K-A-Q-E-E-L-K-E-K-T-V-E-A-T-A-G-G-G-M-V-T-V-V-A-S-G-D-K-R-I-L-D-V-R-I-S-E-D-V-V-D-P-D-D-V-E-M-L-Q-D-L-I-L-A-A-T-N-E-A-L-K-K-V-D-E-L-V-E-Q-D-M-G-K-F-T-K-G-L-N-M-P-G-M-F"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-E-T-P-K-L-S-V-E-A-I-E-K-G-T-V-I-D-H-I-P-A-G-R-G-L-T-I-L-R-Q-F-K-L-L-H-Y-G-N-A-V-T-V-G-F-N-L-P-S-K-T-Q-G-S-K-D-I-I-K-I-K-G-V-C-L-D-D-K-A-A-D-R-L-A-L-F-A-P-E-A-V-V-N-T-I-D-H-F-K-V-V-Q-K-R-H-L-N-L-P-D-E-I-A-E-V-F-R-C-P-N-T-N-C-A-S-H-G-E-P-V-K-S-R-F-Y-V-K-K-H-N-G-Q-T-R-L-K-C-H-Y-C-E-K-T-Y-S-R-D-S-V-A-E-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-I-G-Y-I-K-L-Q-I-P-A-G-K-A-N-P-S-P-P-V-G-P-A-L-G-Q-R-G-L-N-I-M-E-F-C-K-A-F-N-A-A-T-Q-G-M-E-P-G-L-P-I-P-V-V-I-T-A-F-A-D-K-S-F-T-F-V-M-K-T-P-P-A-S-I-L-L-K-K-A-A-G-L-Q-K-G-S-S-N-P-L-T-N-K-V-G-K-L-T-R-A-Q-L-E-E-I-A-K-T-K-E-P-D-L-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-D-V-E-G-V-V"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-G-M-N-Q-Q-R-L-T-Q-V-I-L-A-P-I-V-S-E-K-S-N-V-L-A-E-K-R-N-Q-M-T-F-K-V-L-A-N-A-T-K-P-E-I-K-A-A-V-E-L-L-F-G-V-Q-V-A-S-V-T-T-V-T-T-K-G-K-T-K-R-F-G-R-T-L-G-R-R-S-D-V-K-K-A-Y-V-S-L-A-A-G-Q-E-L-D-L-E-A-A-A-A-A-A-D-K-E"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-R-L-R-E-F-Y-K-E-T-V-V-P-E-L-V-K-Q-F-G-Y-K-S-V-M-E-V-P-R-I-E-K-I-T-L-N-M-G-V-G-E-A-I-A-D-K-K-V-M-E-H-A-V-S-D-L-E-K-I-A-G-Q-K-P-V-V-T-V-A-R-K-S-I-A-G-F-K-I-R-D-N-Y-P-V-G-C-K-V-T-L-R-R-D-Q-M-F-E-F-L-D-R-L-I-T-I-A-L-P-R-V-R-D-F-R-G-V-S-G-K-S-F-D-G-R-G-N-Y-N-M-G-V-R-E-Q-I-I-F-P-E-I-E-Y-D-K-I-D-A-L-R-G-L-N-I-T-I-T-T-T-A-K-T-D-E-E-A-K-A-L-L-S-L-F-K-F-P-F-K-G"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-N-P-V-T-V-P-A-G-V-E-V-K-F-G-T-E-A-L-V-I-K-G-K-N-G-E-L-S-F-P-L-H-S-D-V-A-I-E-F-N-D-G-K-L-T-F-V-A-N-N-S-S-K-Q-A-N-A-M-S-G-T-A-R-A-L-V-S-N-M-V-K-G-V-S-E-G-F-E-K-R-L-Q-L-I-G-V-G-Y-R-A-Q-A-Q-G-K-I-L-N-L-S-L-G-F-S-H-P-I-V-Y-E-M-P-E-G-V-S-V-Q-T-P-S-Q-T-E-I-V-L-T-G-S-D-K-Q-V-V-G-Q-V-A-A-E-I-R-A-F-R-A-P-E-P-Y-K-G-K-G-V-R-Y-V-G-E-V-V-V-M-K-E-A-K-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-F-L-N-T-I-Q-P-A-V-G-A-T-H-A-G-R-R-V-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-K-S-R-S-G-G-F-H-K-V-G-F-E-G-G-Q-M-P-L-Q-R-R-L-P-K-R-G-F-K-S-L-T-A-S-A-N-A-Q-L-R-L-S-E-L-E-S-I-A-V-N-E-I-D-I-L-V-L-K-Q-A-G-L-I-A-S-T-V-S-N-V-K-V-I-A-F-G-E-I-S-K-A-V-A-L-K-G-I-K-V-T-K-G-A-R-A-A-I-E-A-V-G-G-K-I-E-M"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-I-E-F-L-F-G-R-K-Q-K-T-A-T-V-A-R-D-R-L-Q-I-I-I-A-Q-E-R-A-Q-E-G-Q-T-P-D-Y-L-P-T-L-R-K-E-L-M-E-V-L-S-K-Y-V-N-V-S-L-D-N-I-R-I-S-Q-E-K-Q-D-G-M-D-V-L-E-L-N-I-T-L-P-E-Q-K-K-V"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-G-F-Y-A-L-L-L-I-A-L-G-M-S-M-D-A-F-A-V-A-L-A-K-G-A-A-V-R-M-P-P-R-K-I-A-A-T-A-L-V-F-G-S-V-E-A-L-T-P-L-A-G-W-V-G-G-F-Y-A-K-P-F-I-S-E-W-D-H-W-A-A-F-V-L-L-G-G-L-G-L-K-M-M-R-E-G-L-S-G-K-A-E-D-V-R-E-S-K-R-E-S-L-W-M-T-V-L-T-A-F-G-T-S-I-D-S-M-I-V-G-V-G-L-A-F-M-E-V-N-I-A-F-A-A-A-I-I-G-M-A-T-T-V-M-V-A-V-G-L-A-A-G-G-A-L-G-G-L-F-G-K-R-A-E-F-A-G-G-L-V-L-I-A-I-G-T-W-T-L-L-S-H-L-G-L-I-G"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur , and thus conserves the redox energy in a proton gradient ### SEQUENCE -M-A-S-I-Q-N-L-Y-E-T-V-V-G-V-L-G-D-Q-A-S-K-V-I-S-A-L-G-E-I-T-V-E-C-L-P-E-H-Y-I-S-V-M-T-A-L-R-D-H-E-E-L-H-F-E-L-L-V-D-L-C-G-V-D-Y-S-T-Y-K-N-E-V-W-Q-G-K-R-F-A-V-V-S-Q-L-L-S-V-K-N-N-Q-R-I-R-V-R-V-W-V-S-D-D-D-F-P-V-V-E-S-V-V-D-I-Y-N-S-A-D-W-Y-E-R-E-A-F-D-M-Y-G-I-M-F-N-N-H-P-D-L-R-R-I-L-T-D-Y-G-F-V-G-H-P-F-R-K-D-F-P-I-S-G-Y-V-E-M-R-Y-D-E-E-Q-K-R-V-I-Y-Q-P-V-T-I-E-P-R-E-I-T-P-R-I-V-R-E-E-N-Y-G-G-Q"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-K-V-D-H-T-R-M-H-A-P-A-V-R-V-A-K-T-M-T-T-P-K-G-D-T-I-T-V-F-D-L-R-F-C-V-P-N-K-E-I-L-P-G-K-G-I-H-T-L-E-H-L-F-A-G-F-M-R-D-H-L-N-G-N-G-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-T-P-S-E-Q-Q-V-A-D-A-W-L-A-S-M-Q-D-V-L-N-V-K-D-Q-S-K-I-P-E-L-N-E-Y-Q-C-G-T-Y-Q-M-H-S-L-A-E-A-Q-Q-I-A-Q-N-V-L-A-R-K-V-A-V-N-K-N-E-E-L-T-L-D-E-G-L-L-N-A"} +{"text": "### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-V-R-R-L-I-I-G-I-S-G-A-S-G-F-Q-Y-G-V-K-A-L-E-L-L-R-A-Q-D-V-E-T-H-L-V-V-S-K-G-A-E-M-A-R-A-S-E-T-A-Y-A-R-D-E-V-Y-A-L-A-D-F-V-H-P-I-G-N-I-G-A-C-I-A-S-G-T-F-K-T-D-G-M-L-V-A-P-C-S-M-R-T-L-A-S-V-A-H-G-F-G-D-N-L-L-T-R-A-A-D-V-V-L-K-E-R-R-R-L-V-L-M-V-R-E-T-P-L-N-L-A-H-L-D-N-M-K-R-V-T-E-M-G-G-V-V-F-P-P-V-P-A-M-Y-R-K-P-Q-T-A-D-D-I-V-A-H-S-V-A-H-A-L-S-L-F-G-I-D-T-P-D-S-A-E-W-Q-G-M-A-D"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-F-A-T-I-A-R-P-Y-A-K-A-L-F-G-L-A-Q-E-K-N-Q-I-E-S-W-L-G-G-L-E-K-L-A-A-V-V-Q-E-G-K-V-A-S-L-I-D-R-P-E-T-N-A-S-E-K-A-D-I-L-I-D-L-V-G-L-K-D-K-E-L-K-N-F-V-I-V-L-A-G-Q-K-R-L-S-I-L-P-E-V-Y-A-Q-Y-Q-D-L-T-L-S-F-N-H-I-K-S-A-V-I-Y-S-A-Y-P-L-T-D-K-Q-V-G-E-L-V-Q-M-L-N-K-R-F-D-S-E-L-K-I-S-V-E-I-E-P-E-L-I-G-G-I-K-V-E-V-G-D-Q-V-L-D-L-S-V-Q-G-K-L-S-A-L-Y-T-T-M-T-N"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-G-L-E-L-P-L-I-L-G-T-S-S-V-F-R-R-E-Q-M-E-R-L-G-I-A-F-Q-A-A-S-P-D-F-D-E-T-P-M-L-G-E-S-A-P-Q-T-A-L-R-L-A-E-G-K-A-R-S-L-T-G-R-F-P-E-A-L-I-V-G-A-D-Q-V-A-W-C-D-G-R-Q-W-G-K-P-M-N-L-A-N-A-Q-K-M-L-M-H-L-S-G-R-E-I-E-F-Y-S-A-I-V-L-L-N-T-V-T-G-R-M-R-R-H-I-D-K-T-V-V-V-M-R-Q-L-D-E-L-H-I-L-R-Y-L-E-R-E-P-D-A-V-Y-C-S-C-A-L-K-S-E-D-L-G-A-L-L-I-E-R-I-E-S-T-D-P-N-A-L-I-G-L-P-V-F-R-L-V-D-F-L-K-N-E-G-V-E-V-L"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-D-Y-R-F-G-R-Q-Y-R-L-L-K-T-D-D-F-S-S-V-F-A-F-R-N-R-R-S-R-D-L-L-Q-V-S-R-S-N-G-N-G-L-G-H-P-R-I-G-L-V-V-G-K-K-T-A-K-R-A-N-E-R-N-Y-M-K-R-V-I-R-D-W-F-R-L-N-K-N-R-L-P-P-Q-D-F-V-V-R-V-H-R-K-F-D-R-A-T-A-K-Q-A-R-A-E-L-A-Q-L-M-F-G-N-P-A-T-G-C-R-K-Q-A"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-Q-D-K-N-N-L-C-W-L-D-M-E-M-T-G-L-N-P-E-T-D-R-I-I-E-V-A-M-I-I-T-D-S-D-L-N-V-L-A-Q-S-E-V-Y-A-V-H-Q-S-D-D-V-L-N-K-M-D-E-W-N-T-A-T-H-G-R-T-G-L-T-Q-R-V-R-E-S-S-H-T-E-A-E-V-E-Q-K-L-L-D-F-M-S-E-W-V-P-G-R-A-T-P-M-C-G-N-S-I-H-Q-D-R-R-F-M-V-K-Y-M-P-K-L-E-N-Y-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-A-K-R-W-N-P-P-V-A-K-S-V-V-K-R-G-S-H-K-A-L-D-D-I-L-E-S-I-E-E-M-R-H-Y-R-E-H-F-L-I-S-A-P-R-A-E-A-Q"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-F-C-A-H-P-D-T-R-V-A-D-S-R-L-M-E-E-R-N-A-V-R-R-R-R-H-C-P-N-C-G-K-R-F-G-T-L-E-T-A-E-L-K-M-P-A-V-I-G-P-D-K-K-R-S-P-F-N-A-Q-R-L-R-N-D-L-T-A-A-A-R-K-S-A-L-T-P-E-Q-I-D-E-T-V-R-L-T-E-H-R-L-Y-T-S-G-Q-R-D-I-P-S-A-A-L-A-D-M-V-L-K-E-L-L-R-Q-D-T-E-A-A-V-R-F-A-A-L-H-K-R-F-D-N-P-A-D-F-A-S-W-L-A-Q-A-V-K-T-G-G-K-A"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-Q-T-V-T-M-Y-T-G-P-F-C-P-Y-C-A-M-A-K-R-L-L-H-A-A-G-V-G-H-I-D-E-I-R-V-D-A-S-P-E-A-F-A-E-M-Q-Q-L-S-G-Q-R-S-V-P-Q-I-F-I-G-E-T-H-V-G-G-F-T-D-L-Y-R-L-Q-Q-E-G-G-L-D-G-L-L-N-P"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-E-E-L-Q-P-V-F-S-I-E-R-L-Y-V-K-D-L-S-L-E-V-P-H-A-P-Q-I-F-L-E-Q-G-E-P-E-V-E-M-R-V-S-T-G-S-Q-K-L-E-D-G-Y-Y-N-V-D-V-T-V-T-V-T-A-K-L-D-N-E-R-T-M-F-L-N-E-V-T-Q-S-G-I-F-R-L-E-N-I-P-E-E-D-A-D-L-L-L-G-V-A-C-P-N-I-L-F-P-Y-A-R-E-A-V-S-G-T-V-T-R-A-G-F-P-P-V-L-L-A-P-I-N-F-E-A-I-Y-Q-Q-Q-Q-E-A-E-A-A-G-A"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-L-D-R-E-G-Y-R-P-N-V-G-I-I-L-I-N-N-R-N-E-V-F-W-G-K-R-V-R-E-H-S-W-Q-F-P-Q-G-G-I-K-P-G-E-S-P-E-T-A-M-Y-R-E-L-Y-E-E-V-G-L-L-P-Q-H-V-K-I-I-G-R-T-R-D-W-L-R-Y-D-V-P-N-N-W-V-R-R-E-W-R-G-S-Y-R-G-Q-K-Q-I-W-Y-L-L-R-L-T-G-R-D-C-D-V-N-L-R-A-T-R-H-P-E-F-D-G-W-R-W-H-Q-Y-W-A-P-V-D-E-V-I-D-F-K-R-D-V-Y-L-G-A-L-K-E-L-S-S-R-F-L-R-G-M-E-S-Y-E-D-F-A-A-R-Q-S-S-D-N-R"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-T-P-L-F-R-K-A-V-W-L-L-F-A-V-S-V-C-A-F-A-G-S-L-A-A-Q-Y-V-L-G-M-E-P-C-V-L-C-I-S-Q-R-L-C-V-L-A-T-A-L-C-T-A-I-V-L-M-C-R-P-R-R-R-A-G-G-L-F-G-A-V-F-I-S-I-P-A-V-T-G-I-S-V-A-A-Y-Q-L-W-L-Q-S-L-P-P-G-T-A-P-S-C-G-A-P-W-T-F-R-L-K-G-W-P-L-F-D-W-F-E-P-V-V-R-G-F-G-N-C-A-E-P-D-Y-L-L-G-I-A-L-P-V-W-S-V-A-Y-F-L-A-V-V-L-T-V-W-W-A-W-A-R-A-K"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-K-P-Q-K-S-L-R-A-R-A-M-D-I-L-S-R-Q-E-L-S-R-I-G-L-K-R-K-L-A-P-H-A-E-S-E-E-E-L-E-N-V-L-N-E-F-A-E-R-N-W-Q-S-D-L-R-Y-A-E-A-Y-I-R-S-K-S-R-K-H-G-S-L-R-L-K-Q-A-L-A-Q-Q-G-I-D-E-E-T-S-R-N-L-L-P-D-R-S-S-E-K-L-A-A-I-A-V-L-R-K-K-F-K-H-P-A-A-D-L-K-E-K-Q-K-Q-A-R-F-L-A-Y-R-G-F-D-A-D-T-V-Q-T-A-L-K-H-A-W-D-D-G-W-E-E-D-C"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-A-G-L-G-G-L-M-K-Q-A-Q-Q-M-Q-E-N-M-K-K-A-Q-A-K-L-A-E-T-E-I-E-G-E-A-G-N-G-L-V-K-I-T-M-T-C-A-H-E-V-R-K-I-D-I-S-P-D-L-I-Q-E-A-A-D-D-K-E-M-L-E-D-L-I-L-A-A-L-K-S-A-R-G-K-A-E-E-T-A-N-K-T-M-G-A-F-T-Q-G-L-P-P-G-V-G-D-F-F-R"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-Q-K-I-P-L-T-V-R-G-A-E-L-L-K-Q-E-L-Q-Q-L-K-S-V-A-R-P-E-V-I-E-A-I-A-E-A-R-S-H-G-D-L-S-E-N-A-E-Y-E-A-A-K-E-R-Q-G-F-I-E-G-R-I-S-E-L-E-H-K-L-S-V-A-H-I-I-N-P-T-E-I-H-A-E-G-K-I-V-F-G-T-T-V-T-L-E-D-L-E-T-E-E-H-V-I-Y-Q-I-V-G-E-D-E-A-D-I-K-Q-G-K-I-Y-V-G-S-P-I-A-R-A-L-I-G-K-E-E-G-D-T-A-E-V-Q-A-P-G-G-V-R-E-Y-D-I-I-E-V-R-Y-I"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-S-Q-Y-F-T-L-F-R-I-E-P-A-F-D-I-D-T-E-N-L-E-Q-T-Y-R-A-L-A-A-R-F-H-P-D-K-F-A-S-A-S-A-F-E-Q-K-Q-A-V-M-M-S-S-T-I-N-D-A-Y-R-T-L-K-N-P-I-D-R-A-A-Y-L-L-K-T-S-G-I-D-A-D-A-P-E-H-T-A-F-A-P-E-F-L-M-Q-Q-M-E-W-R-E-T-L-M-E-A-R-A-G-N-D-L-E-S-L-K-N-L-D-N-E-I-R-D-E-Q-E-K-L-F-C-G-L-K-Q-S-F-A-R-Q-D-Y-D-T-A-A-Q-Q-V-R-Q-G-R-F-L-D-K-L-R-N-E-I-S-S-A-L"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-R-K-P-Q-R-G-Y-A-R-Q-D-R-V-K-E-Q-I-M-R-E-L-A-E-L-V-R-T-G-L-K-D-P-R-A-G-F-I-T-V-N-E-V-E-V-T-R-D-Y-S-H-A-T-V-F-Y-T-I-L-N-Q-D-A-R-E-I-T-E-E-V-L-E-H-A-R-G-H-L-R-S-E-L-A-K-R-I-K-L-F-K-T-P-E-L-H-F-K-Y-D-E-S-L-E-R-G-L-N-L-S-A-L-I-D-Q-V-A-A-E-K-P-V-E-D"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-H-K-I-P-K-G-T-A-L-A-F-D-F-G-E-A-R-I-G-V-A-Q-G-D-A-E-L-G-L-S-H-P-L-S-T-V-T-G-G-S-N-D-E-K-F-A-A-I-A-K-L-V-Q-E-W-Q-P-R-Y-F-V-V-G-L-P-V-H-T-D-G-T-K-H-E-M-T-H-L-S-R-K-F-G-R-R-L-N-G-R-F-N-L-P-V-Y-W-V-D-E-R-L-S-S-V-Y-A-E-S-L-L-S-E-A-Q-V-F-G-K-K-R-K-S-V-L-D-Q-V-A-A-Q-A-I-L-H-G-F-F-E-G-G-P-A-E-C-F-N-G-R-E-G"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-I-V-H-P-D-Q-S-E-Q-V-P-A-M-V-E-R-Y-K-T-M-I-A-E-A-N-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-I-H-K-A-H-Y-V-L-M-N-I-E-T-T-P-E-V-V-E-E-L-E-T-A-F-R-F-N-D-A-I-L-R-H-L-T-I-K-T-K-H-A-V-T-E-A-S-P-M-L-G-G-E-K-A-K-N-L-L-S-G-A-S-E-E-A-V-A-Q"} +{"text": "### FUNCTION Stimulates the DNA unwinding activity of PriA helicase, which does not seem to require single-stranded DNA-binding by PriB Activates DNA-dependent ATP hydrolysis catalyzed by PriA ### SEQUENCE -M-G-F-N-N-L-V-S-L-A-A-L-I-E-K-V-F-P-I-R-Y-T-P-A-G-I-P-V-L-D-I-I-L-K-H-E-S-W-Q-E-E-N-G-Q-Q-C-L-V-Q-L-E-I-P-A-R-I-L-G-R-Q-A-E-E-W-Q-Y-R-Q-G-V-Y-V-H-V-E-G-F-L-A-Q-K-S-R-R-S-L-M-P-M-L-R-I-Q-N-I-Q-E-Y-K-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-E-K-I-G-G-L-G-N-L-G-D-I-V-T-V-K-N-G-Y-A-R-N-F-L-I-P-A-G-K-A-K-R-A-T-E-A-N-M-K-E-F-E-A-R-R-A-E-L-E-A-K-Q-A-E-I-L-A-D-A-R-V-R-Q-E-K-L-D-G-Q-T-V-T-V-A-Q-K-A-G-V-D-G-R-L-F-G-S-V-T-N-A-D-I-A-A-A-I-V-A-A-G-I-E-A-V-K-A-N-V-R-L-P-N-G-P-L-K-A-V-G-E-Y-E-V-E-V-A-L-H-T-D-A-V-A-K-I-T-V-A-V-V-A-A-T-E"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-S-N-I-I-P-L-S-I-G-A-A-L-G-A-T-A-R-W-L-L-N-L-A-V-P-A-S-I-P-P-A-T-G-N-L-F-A-N-W-I-G-A-F-L-I-G-I-F-A-E-T-V-N-H-P-Q-W-K-L-L-L-I-T-G-F-L-G-S-L-T-T-L-S-G-F-S-L-E-T-V-T-L-L-Q-L-N-R-P-A-S-A-L-A-N-I-F-L-H-T-A-G-S-L-L-L-T-W-L-G-L-K-I-G-A-A-V-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-T-A-Q-E-L-R-A-G-N-V-F-M-V-G-N-D-P-M-V-V-Q-K-T-E-Y-I-K-G-G-R-S-S-A-K-V-S-M-K-L-K-N-L-L-T-G-A-A-S-E-T-I-Y-K-A-D-D-K-F-D-V-V-I-L-S-R-K-N-C-T-Y-S-Y-F-A-D-P-M-Y-V-F-M-D-E-E-F-N-Q-Y-E-I-E-A-D-N-I-G-D-A-L-K-F-I-V-D-G-M-E-D-Q-C-E-V-T-F-Y-E-G-N-P-I-S-V-E-L-P-T-I-I-V-R-E-V-E-Y-T-E-P-A-V-K-G-D-T-S-G-K-V-M-K-T-A-R-L-V-G-G-T-E-I-Q-V-M-S-Y-I-E-N-G-D-K-V-E-I-D-T-R-T-G-E-F-R-K-R-A"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-N-I-E-V-E-M-K-V-L-D-E-R-M-A-D-V-V-P-V-Y-A-T-E-G-S-A-G-L-D-L-R-A-C-L-D-E-E-V-V-L-Q-P-G-E-T-F-L-V-P-T-G-L-A-I-Y-L-A-N-P-A-Y-A-A-V-L-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-E-L-K-V-S-L-W-N-R-S-S-E-P-F-T-V-K-P-F-E-R-I-A-Q-M-V-V-V-P-I-V-Q-A-G-F-K-R-V-E-E-F-V-G-S-S-R-G-E-G-G-F-G-S-T-G-S-H"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-T-Y-E-I-Q-A-S-V-R-E-A-Q-G-T-G-A-S-R-R-L-R-R-E-G-Q-I-P-G-I-L-Y-G-E-G-Q-E-P-V-A-I-A-V-D-H-K-T-V-F-Y-A-L-E-K-E-S-F-H-T-A-L-I-K-L-S-L-N-G-E-T-K-D-V-I-V-R-D-F-Q-M-H-P-F-R-R-E-V-Q-H-I-D-F-Q-A-V-K-A-D-Q-L-V-R-I-R-V-P-L-H-I-V-N-A-E-N-S-Q-A-V-K-L-Q-G-G-R-V-S-L-L-N-T-S-V-E-V-V-A-L-P-A-N-I-P-A-F-L-D-L-D-C-A-E-V-V-A-G-D-I-L-H-L-S-D-I-K-L-P-E-G-V-E-S-V-S-L-K-R-N-E-N-L-A-V-A-T-V-T-G-K-K-R"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-T-A-Q-H-Q-S-D-T-L-L-H-R-L-N-T-L-P-P-K-R-Y-G-V-F-L-L-N-D-D-Y-T-T-M-E-F-V-V-E-I-L-T-E-I-F-M-L-G-Q-E-Q-A-V-A-V-M-L-L-V-H-H-E-G-K-G-L-C-G-T-Y-T-R-D-I-A-Q-T-K-Q-Q-Q-V-M-Q-R-A-K-A-E-G-H-P-L-Q-C-I-V-E-E-I"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-N-T-I-K-M-V-V-G-L-G-N-P-G-K-E-Y-E-Q-T-R-H-N-A-G-F-W-F-L-D-E-L-A-W-K-W-K-A-S-F-K-E-E-K-K-F-F-G-E-V-A-R-A-A-L-P-D-G-D-V-W-L-L-K-P-A-T-F-M-N-R-S-G-Q-A-V-A-A-L-A-Q-F-Y-K-I-K-P-E-E-I-L-V-V-H-D-E-L-D-I-P-C-G-R-I-K-F-K-L-G-G-G-N-G-G-H-N-G-L-K-D-I-Q-A-K-L-G-T-A-D-Y-Y-R-L-R-L-G-I-G-H-P-G-D-R-N-L-V-V-G-Y-V-L-N-K-P-S-T-E-H-R-R-Q-I-D-D-A-V-A-K-S-L-Q-A-I-P-D-I-L-A-G-K-W-E-E-A-T-R-F-L-H-S-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-R-A-R-H-Q-K-I-F-A-L-A-K-G-Y-R-G-R-R-K-N-V-Y-R-V-A-K-Q-A-V-M-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-Q-L-W-I-V-R-I-N-A-G-T-R-E-N-G-L-S-Y-S-K-F-M-N-G-L-K-R-A-S-I-E-I-D-R-K-V-L-A-D-L-A-V-F-D-K-A-A-F-A-Q-L-V-E-K-A-K-A-A-L-A-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-S-T-E-T-K-N-Y-I-T-P-A-G-W-Q-A-L-K-D-E-L-Y-Q-L-V-N-K-E-R-P-E-I-V-Q-I-V-N-W-A-A-G-N-G-D-R-S-E-N-G-D-Y-L-Y-G-K-R-R-M-R-E-I-D-R-R-I-R-F-L-T-K-R-L-E-A-A-V-V-V-D-P-E-L-R-E-A-T-D-Q-V-F-F-G-A-T-V-G-L-L-R-D-D-G-R-E-Q-T-V-K-I-V-G-I-D-E-I-D-T-A-Q-N-K-I-S-W-I-S-P-L-A-R-C-L-I-K-A-R-E-G-D-E-V-V-L-N-T-P-E-G-R-E-E-I-E-I-L-S-V-E-Y-I-K-I-D"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-T-A-R-R-R-S-R-E-L-A-V-Q-A-V-Y-Q-S-L-I-N-R-T-A-A-P-E-I-A-K-N-I-R-E-M-S-D-F-A-K-A-D-E-E-L-F-N-K-L-F-F-G-T-Q-T-N-A-A-E-Y-I-R-Q-I-R-P-L-L-D-R-D-E-K-D-L-N-P-I-E-R-A-V-L-L-T-A-C-H-E-L-S-A-M-P-E-T-P-Y-P-V-I-I-N-E-A-I-E-V-T-K-T-F-G-G-T-D-G-H-K-F-V-N-G-I-L-D-K-L-A-A-Q-I-R-P-D-E-P-K-R-R"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-D-T-Q-N-R-V-A-M-G-Y-I-K-G-V-F-G-I-K-G-W-L-K-I-A-A-N-T-E-Y-S-D-S-L-L-D-Y-P-E-W-H-L-V-K-D-G-K-T-I-S-V-T-L-E-A-G-K-V-V-N-G-E-L-Q-V-K-F-E-G-I-N-D-R-D-L-A-F-S-L-R-G-Y-T-I-E-I-P-R-E-A-F-A-P-T-E-E-D-E-Y-Y-W-T-D-L-V-G-M-T-V-V-N-K-D-H-T-V-L-G-K-V-S-N-L-M-E-T-G-A-N-D-V-L-M-I-D-G-E-H-G-Q-I-L-I-P-F-V-S-Q-Y-I-E-T-V-D-T-G-S-K-T-I-T-A-D-W-G-L-D-Y"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-L-I-Q-Q-L-E-Q-E-E-I-A-R-L-N-K-E-I-P-E-F-A-P-G-D-T-V-V-V-S-V-R-V-V-E-G-T-R-S-R-L-Q-A-Y-E-G-V-V-I-A-R-R-N-R-G-L-N-S-N-F-I-V-R-K-I-S-S-G-E-G-V-E-R-T-F-Q-L-Y-S-P-T-V-E-K-I-E-V-K-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-G-L-T-G-K-A-A-R-I-K-E-K-L-P-A-R-K-G"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-N-I-P-A-E-L-K-Y-V-A-S-H-E-W-L-R-L-E-E-D-G-T-I-T-V-G-I-T-H-H-A-Q-E-L-L-G-D-I-V-F-V-E-L-P-E-V-G-A-N-L-A-A-E-E-Q-A-G-V-V-E-S-V-K-A-A-S-D-V-Y-A-P-I-A-G-E-V-V-A-V-N-E-D-L-P-S-A-P-E-T-A-N-S-D-P-Y-G-A-G-W-F-F-K-L-K-P-A-N-V-A-D-Y-D-S-L-L-T-A-E-Q-Y-A-G-E-V-D"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-K-R-T-K-K-Y-P-F-L-T-L-Q-R-Q-R-F-H-L-N-F-E-N-A-S-S-A-A-G-I-P-A-E-R-D-F-Y-R-W-A-W-S-A-L-K-N-E-Y-R-R-A-D-I-S-L-I-L-L-D-E-E-E-A-R-A-Y-N-R-D-Y-R-G-K-D-Y-A-T-N-V-L-S-F-A-L-N-E-G-E-I-L-P-C-Q-V-S-E-K-L-Y-G-D-L-I-I-C-P-Q-V-V-L-K-E-A-A-E-Q-G-K-T-P-E-Q-H-F-A-H-L-T-I-H-G-T-L-H-L-M-G-Y-D-H-I-E-D-D-E-A-E-I-M-E-A-E-E-I-R-L-M-R-A-A-G-F-P-N-P-Y-Q-E-D"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-T-E-S-R-Q-T-R-L-Q-V-K-C-P-T-C-Q-T-A-V-V-W-K-P-E-N-A-F-R-P-F-C-S-Q-R-C-K-L-I-D-L-G-G-W-A-D-G-K-Y-T-V-S-G-Q-T-E-S-L-P-E-I-S-E-P-D-M-A-Y-R"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-S-R-L-T-G-K-L-V-E-K-N-P-P-Q-I-V-I-D-V-N-G-V-G-Y-E-A-D-V-S-M-Q-T-F-Y-N-L-P-P-V-G-E-S-V-Q-L-F-T-Q-L-I-I-R-E-D-A-H-L-L-F-G-F-A-T-A-E-E-R-K-T-F-R-Q-L-I-K-V-G-G-I-G-A-K-T-A-L-G-I-L-S-A-M-T-A-D-E-L-A-R-A-V-A-E-E-D-V-K-R-L-S-S-A-P-G-I-G-K-K-T-A-E-R-M-V-L-E-L-R-G-K-L-V-A-H-T-V-T-D-G-L-F-A-A-A-P-A-A-D-E-T-E-D-I-V-S-T-L-L-A-L-G-Y-S-E-R-E-A-K-A-A-V-K-G-V-P-E-G-T-D-V-G-E-G-V-R-L-A-L-K-N-L-L-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-K-K-N-A-P-K-S-F-E-E-A-L-S-R-L-E-S-L-T-Q-S-M-Q-G-E-M-P-L-E-D-A-L-A-A-Y-Q-E-G-N-E-L-V-R-Y-C-Q-T-K-L-A-Q-V-E-Q-K-L-Q-V-L-D-T-D-G-L-K-E-L-N-L-E-S-D-E"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur , and thus conserves the redox energy in a proton gradient ### SEQUENCE -M-A-S-I-Q-D-L-Y-E-T-V-S-R-V-L-G-N-Q-A-G-K-V-I-S-A-L-G-E-I-T-V-E-C-L-P-E-H-Y-I-S-V-M-T-A-L-R-D-H-E-E-L-H-F-E-L-L-V-D-L-C-G-V-D-Y-S-T-Y-K-N-E-A-W-Q-G-K-R-F-A-V-V-S-Q-L-L-S-V-K-N-N-Q-R-I-R-V-R-V-W-V-S-D-D-D-F-P-V-V-E-S-V-V-D-I-Y-N-S-A-D-W-Y-E-R-E-A-F-D-M-Y-G-I-M-F-N-N-H-P-D-L-R-R-I-L-T-D-Y-G-F-V-G-H-P-F-R-K-D-F-P-I-S-G-Y-V-E-M-R-Y-D-E-E-Q-K-R-V-I-Y-Q-P-V-T-I-E-P-R-E-I-T-P-R-I-V-R-E-E-N-Y-G-G-Q"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-G-F-Y-A-L-L-L-I-A-L-G-M-S-M-D-A-F-A-V-A-L-A-K-G-A-A-V-R-M-P-P-R-K-I-A-A-T-A-L-V-F-G-T-V-E-A-L-T-P-L-A-G-W-V-G-G-F-Y-A-K-P-F-I-S-E-W-D-H-W-V-A-F-V-L-L-G-G-L-G-L-K-M-M-R-E-G-L-S-G-E-A-E-D-V-R-E-S-K-R-E-S-L-W-M-T-V-L-T-A-F-G-T-S-I-D-S-M-I-V-G-V-G-L-A-F-M-E-V-N-I-A-F-A-A-A-I-I-G-M-A-T-T-V-M-V-A-V-G-L-T-A-G-R-A-L-G-V-L-F-G-R-C-A-E-F-A-G-G-L-V-L-I-A-I-G-T-W-T-L-L-S-H-L-G-L-I-Q"} +{"text": "### FUNCTION Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ### SEQUENCE -M-N-K-T-L-I-L-A-L-S-A-L-L-G-L-A-A-C-S-A-E-R-V-S-L-F-P-S-Y-K-L-K-I-I-Q-G-N-E-L-E-P-R-A-V-A-A-L-R-P-G-M-T-K-D-Q-V-L-L-L-L-G-S-P-I-L-R-D-A-F-H-T-D-R-W-D-Y-T-F-N-T-S-R-N-G-I-I-K-E-R-S-N-L-T-V-Y-F-E-N-G-V-L-V-R-T-E-G-D-V-L-Q-N-A-A-E-A-L-K-D-R-Q-N-T-D-K-P"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-I-E-F-L-F-G-R-K-Q-K-T-A-T-V-A-R-D-R-L-Q-I-I-I-A-Q-E-R-A-Q-E-G-Q-A-P-D-Y-L-P-T-L-R-K-E-L-M-E-V-L-S-K-Y-V-N-V-S-L-D-N-I-R-I-S-Q-E-K-Q-D-G-M-D-V-L-E-L-N-I-T-L-P-E-Q-K-K-V"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-F-L-N-T-I-Q-P-A-V-G-A-T-H-A-G-R-R-V-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-K-S-R-S-G-G-F-H-K-V-G-F-E-G-G-Q-M-P-L-Q-R-R-L-P-K-R-G-F-K-S-L-T-A-S-A-N-A-Q-L-R-L-S-E-L-E-S-I-A-V-N-E-I-D-I-L-V-L-K-Q-A-G-L-I-A-S-T-V-S-N-V-K-V-I-A-S-G-E-I-S-K-A-V-A-L-K-G-I-K-V-T-K-G-A-R-A-A-I-E-A-V-G-G-K-I-E-M"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-N-P-V-T-V-P-A-G-V-E-V-K-F-G-A-E-A-L-V-I-K-G-K-N-G-E-L-S-F-P-L-H-S-D-V-A-I-E-F-N-D-G-K-L-T-F-V-A-N-N-S-S-K-Q-A-N-A-M-S-G-T-A-R-A-L-V-S-N-M-V-K-G-V-S-E-G-F-E-K-R-L-Q-L-I-G-V-G-Y-R-A-Q-A-Q-G-K-I-L-N-L-S-L-G-F-S-H-P-I-V-Y-E-M-P-E-G-V-S-V-Q-T-P-S-Q-T-E-I-V-L-T-G-S-D-K-Q-V-V-G-Q-V-A-A-E-I-R-A-F-R-A-P-E-P-Y-K-G-K-G-V-R-Y-V-G-E-V-V-V-M-K-E-A-K-K-K"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-R-L-R-E-F-Y-K-E-T-V-V-P-E-L-V-K-Q-F-G-Y-K-S-V-M-E-V-P-R-I-E-K-I-T-L-N-M-G-V-G-E-A-V-A-D-K-K-V-M-E-H-A-V-S-D-L-E-K-I-A-G-Q-K-P-V-V-T-V-A-R-K-S-I-A-G-F-K-I-R-D-N-Y-P-V-G-C-K-V-T-L-R-R-D-Q-M-F-E-F-L-D-R-L-I-T-I-A-L-P-R-V-R-D-F-R-G-V-S-G-K-S-F-D-G-R-G-N-Y-N-M-G-V-R-E-Q-I-I-F-P-E-I-E-Y-D-K-I-D-A-L-R-G-L-N-I-T-I-T-T-T-A-K-T-D-E-E-A-K-A-L-L-S-L-F-K-F-P-F-K-G"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-Q-Q-R-L-T-Q-V-I-L-A-P-I-V-S-E-K-S-N-V-L-A-E-K-R-N-Q-M-T-F-K-V-L-A-N-A-T-K-P-E-I-K-A-A-V-E-L-L-F-G-V-Q-V-A-D-V-T-T-V-T-I-K-G-K-V-K-R-F-G-R-T-L-G-R-R-S-D-V-K-K-A-Y-V-S-L-A-A-G-Q-E-L-D-L-E-A-A-A-A-A-A-D-K-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-I-G-Y-I-K-L-Q-I-P-A-G-K-A-N-P-S-P-P-V-G-P-A-L-G-Q-R-G-L-N-I-M-E-F-C-K-A-F-N-A-A-T-Q-G-M-E-P-G-L-P-I-P-V-V-I-T-A-F-A-D-K-S-F-T-F-V-M-K-T-P-P-A-S-I-L-L-K-K-A-A-G-L-Q-K-G-S-S-N-P-L-T-N-K-V-G-K-L-T-R-A-Q-L-E-E-I-A-K-T-K-D-P-D-L-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-D-V-E-G-V-V"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-E-T-P-K-L-S-V-E-A-I-E-K-G-T-V-I-D-H-I-P-A-G-R-G-L-T-I-L-R-Q-F-K-L-L-H-Y-G-N-A-V-T-V-G-F-N-L-P-S-K-T-Q-G-S-K-D-I-I-K-I-K-G-V-C-L-D-D-K-A-A-D-R-L-A-L-F-A-P-E-A-V-V-N-T-I-D-N-F-K-V-V-Q-K-R-H-L-N-L-P-D-E-I-A-E-V-F-R-C-P-N-T-N-C-A-G-H-G-E-P-V-K-S-R-F-Y-V-K-K-H-N-G-Q-T-R-L-K-C-H-Y-C-E-K-T-Y-S-R-D-S-V-A-E-A"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-E-E-V-P-F-E-N-A-M-Q-R-L-E-E-I-V-D-L-M-N-Q-P-T-T-S-L-D-A-S-L-A-L-Y-E-E-A-D-A-L-M-R-I-C-E-S-R-I-R-Q-V-E-Q-R-V-R-E-L-A-E-K-R-H-E-S-S-L-F-E-E-Q-A-V-V-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-N-H-R-I-D-R-V-G-M-E-I-K-R-E-V-N-E-I-L-R-L-R-V-N-D-P-R-V-Q-D-V-T-I-T-D-V-Q-M-L-G-D-L-S-M-A-K-V-F-Y-T-I-H-S-T-L-A-S-D-N-Q-K-A-Q-I-G-L-E-K-A-T-G-T-I-K-R-E-L-G-K-N-L-T-M-Y-K-I-P-D-L-Q-F-V-K-D-E-S-I-E-Y-G-N-K-I-D-E-M-L-R-N-L-D-K-K-D"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-D-V-T-T-D-A-G-A-P-W-L-V-A-G-L-G-N-P-G-P-E-Y-A-S-N-R-H-N-V-G-F-M-V-A-D-L-L-A-E-R-I-G-A-R-F-K-R-H-G-K-A-Q-A-Q-V-V-E-G-R-I-G-P-P-G-P-A-N-R-R-V-I-L-A-K-P-M-S-F-M-N-V-S-G-G-P-V-T-A-L-R-D-F-Y-K-V-P-V-G-N-I-V-A-V-H-D-E-L-D-I-D-Y-G-V-L-R-L-K-L-G-G-G-D-N-G-H-N-G-L-K-S-I-T-K-S-L-G-A-D-Y-H-R-V-R-F-G-I-G-R-P-P-G-R-M-P-V-A-D-F-V-L-R-D-F-S-S-T-E-R-K-E-L-D-Y-F-V-D-R-A-A-D-A-V-E-A-L-V-I-E-G-L-E-R-A-Q-S-A-Y-N-S"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-S-E-V-K-L-T-A-E-T-R-T-E-F-G-K-G-A-A-R-R-I-R-R-D-N-K-V-P-G-V-L-Y-G-H-G-S-D-P-L-H-L-T-L-P-G-H-E-L-L-L-A-L-R-T-S-N-V-L-I-A-L-D-I-D-G-K-T-N-E-L-A-I-P-K-S-V-Q-R-D-P-I-K-G-F-L-E-H-V-D-L-Q-L-V-K-R-G-E-T-V-S-V-E-I-P-V-Q-A-E-G-E-L-A-P-G-G-F-L-L-E-Y-V-L-D-A-L-P-V-E-A-E-A-T-H-I-P-Q-Q-V-T-V-S-V-A-G-L-E-A-G-A-S-I-H-A-K-D-I-A-L-P-S-G-V-K-L-D-V-D-G-D-T-V-V-L-Q-V-L-S-A-Q-A-E-E-A-P-A-E-G-E-G-E-G-E-G-A-A-E-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-P-M-L-Q-I-A-A-E-E-M-E-N-P-L-I-P-P-I-P-E-L-V-I-G-L-I-A-F-V-I-V-F-G-F-L-A-K-K-L-L-P-N-I-N-K-V-L-E-E-R-R-E-A-I-E-G-G-I-E-K-A-E-A-A-Q-T-E-A-Q-S-V-L-E-Q-Y-K-A-Q-L-A-E-A-R-H-E-A-A-R-L-R-Q-E-A-Q-E-Q-G-A-T-L-I-A-E-M-R-A-E-G-Q-R-Q-R-E-E-I-I-A-A-G-H-A-Q-I-Q-A-D-R-K-A-A-A-S-A-L-R-Q-D-V-G-K-L-A-T-E-L-A-G-K-L-V-G-E-S-L-E-D-H-A-R-Q-S-R-V-I-D-R-F-L-D-E-L-D-D-K-A-T-T-A-E-A-T-R"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-K-Y-E-I-M-Y-I-I-A-P-N-L-E-E-A-A-N-K-E-I-I-E-R-F-N-G-V-L-T-N-Q-G-A-E-I-E-K-V-E-E-M-G-K-R-R-L-A-Y-E-I-N-K-F-R-E-G-Y-Y-V-L-L-N-V-K-A-D-A-D-A-I-A-E-F-N-R-L-I-K-I-N-D-N-V-I-R-V-L-I-T-K-D-E-E"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-L-N-R-V-V-L-V-G-R-L-T-R-D-P-E-L-R-Y-T-P-N-G-V-A-V-A-N-F-T-L-A-V-N-R-P-F-S-N-Q-Q-G-E-R-E-A-D-F-I-N-C-V-V-W-R-K-Q-A-E-N-V-A-N-Y-L-K-K-G-S-L-A-G-V-D-G-R-I-Q-T-R-S-Y-D-N-N-E-G-R-R-V-F-V-T-E-V-M-A-E-S-V-Q-F-L-E-P-R-G-S-Q-S-Q-G-G-S-N-V-D-N-F-G-G-G-S-P-N-N-P-M-G-G-N-D-F-G-Q-Q-S-G-G-S-G-R-Q-S-G-G-F-S-E-D-P-F-A-N-D-G-K-P-I-D-I-S-D-D-D-L-P-F"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-R-G-R-P-K-R-R-K-V-C-Y-F-T-V-N-K-I-E-K-I-D-Y-K-D-V-D-L-L-K-K-F-V-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-Y-Q-R-Q-L-T-T-A-I-K-R-A-R-Q-I-A-L-L-P-Y-V-T-D-N-N"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-Q-Q-D-V-K-G-K-G-K-K-G-E-V-K-N-V-S-E-G-Y-A-R-N-Y-L-I-P-N-G-L-A-V-E-A-T-S-A-N-M-K-N-L-N-A-K-K-K-S-E-E-K-K-K-E-E-E-L-Q-E-A-K-A-Y-Q-T-E-L-E-A-L-T-L-E-L-K-A-K-S-G-E-G-G-R-L-F-G-A-I-S-T-K-Q-I-A-E-A-L-S-R-E-G-K-K-V-D-K-R-K-I-L-L-N-D-P-I-R-S-L-G-Y-T-N-V-P-I-K-I-H-P-E-V-T-A-T-V-K-V-H-V-V-E-E"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-N-I-S-I-I-S-V-G-K-L-K-E-K-Y-L-K-Q-G-I-A-E-Y-T-K-R-L-G-A-Y-A-K-I-E-L-I-E-V-P-D-E-K-A-P-E-Q-L-S-D-T-E-M-E-H-V-K-Q-K-E-G-E-R-I-L-A-K-L-H-P-D-T-Y-V-I-A-L-A-I-E-G-S-M-K-S-S-E-E-L-A-D-T-M-D-R-L-A-T-Y-G-K-S-K-V-A-F-V-I-G-G-S-L-G-L-S-D-A-V-L-K-R-A-D-E-K-L-S-F-S-K-M-T-F-P-H-R-L-M-R-L-I-L-L-E-Q-V-Y-R-A-F-R-I-N-R-G-E-P-Y-H-K"} +{"text": "### FUNCTION The phosphoenolpyruvate-dependent sugar phosphotransferase system , a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane The enzyme II CmtAB PTS system is involved in D-mannitol transport ### SEQUENCE -M-S-Q-T-I-L-S-T-E-T-I-K-V-K-A-E-A-R-S-K-E-E-A-I-K-A-A-G-T-L-L-V-E-K-G-Y-V-E-P-N-Y-V-D-K-M-F-E-R-E-T-V-T-S-T-Y-L-G-N-Y-L-A-I-P-H-G-T-E-E-A-K-E-Q-V-I-H-S-G-M-S-V-L-V-F-D-D-P-V-D-W-D-G-Q-E-V-R-V-V-I-G-I-A-G-K-G-T-E-H-L-D-I-L-S-K-I-A-I-T-F-S-E-E-E-N-V-E-R-L-L-S-L-E-S-A-Q-E-V-L-A-F-L-G-E-V-N-E"} +{"text": "### FUNCTION Probable spore cortex-lytic enzyme involved in the depolymerization of cortex peptidoglycan during germination ### SEQUENCE -M-A-V-I-R-T-T-S-R-D-I-D-L-L-A-R-L-M-R-A-E-A-E-G-E-G-D-L-G-M-L-M-A-G-N-V-M-V-N-R-V-R-V-G-C-L-D-F-A-D-I-N-T-V-E-R-M-V-F-Q-S-P-G-G-F-E-A-T-Q-K-G-Y-F-Y-Q-R-A-R-E-K-E-R-R-L-A-Q-R-I-V-N-G-E-R-T-H-P-A-E-F-S-L-W-F-F-R-P-D-G-P-C-P-E-Q-W-Y-G-Q-W-N-S-G-R-Y-K-A-H-C-F-F-N-P-T-S-A-D-C-P-E-V-Y-G-V-F"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-K-L-A-E-L-S-K-E-E-I-Q-E-L-S-M-V-E-V-A-Y-L-V-M-K-E-T-K-E-P-F-N-Y-Q-D-L-L-K-K-V-A-E-L-K-G-M-S-E-E-Q-M-L-D-R-I-G-Y-L-Y-T-D-L-N-I-D-G-R-F-V-T-L-G-D-N-R-W-G-L-R-S-W-Y-P-L-E-Q-V-E-E-E-I-T-G-P-T-K-K-K-A-K-A-K-A-E-E-E-V-D-E-L-D-E-N-I-E-V-F-D-D-E-F-E-D-L-E-D-E-L-D-E-L-A-E-S-E-D-S-D-E-E-D-E-E-F-D-E-G-D-D-I-D-E-L-D-D-E-F-E-E-S-D-D-D-L"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-V-E-E-L-I-A-L-L-I-M-A-S-A-L-G-M-D-A-F-S-I-A-L-G-M-G-T-L-G-L-R-F-S-Q-M-F-K-V-G-L-T-I-G-V-F-H-V-I-M-P-L-M-G-M-V-A-G-K-L-L-S-A-H-L-G-L-F-A-N-W-L-G-A-G-L-L-L-W-L-G-L-V-M-I-V-S-P-F-Q-E-K-E-R-T-F-V-D-P-S-G-I-G-L-F-V-F-A-L-S-V-S-L-D-S-L-S-A-G-L-S-L-G-M-V-G-A-K-M-A-L-A-V-V-A-M-G-V-M-S-T-V-L-S-W-L-G-L-F-I-G-M-R-F-Q-R-Y-V-G-P-Y-S-E-L-L-G-G-F-I-L-C-G-F-G-V-K-L-L-L-P-Y"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-F-D-I-N-W-G-S-I-I-Y-Q-L-I-A-F-C-V-L-L-W-L-L-S-K-F-A-L-K-P-L-M-G-V-M-E-K-R-E-Q-M-I-N-D-Q-I-D-Q-A-D-K-D-R-K-A-A-Q-E-Y-L-E-Q-Q-R-L-A-V-E-K-A-R-E-E-A-Q-E-I-V-Q-K-A-K-K-L-S-E-Q-Q-G-Q-E-I-V-E-A-A-R-A-E-G-E-R-L-K-E-A-A-L-A-E-I-Q-R-E-K-E-Q-A-V-A-S-L-R-E-Q-V-A-S-L-S-V-L-I-A-T-K-V-I-E-K-E-L-D-E-K-E-Q-E-K-L-I-A-E-Y-L-K-E-V-G-E-E-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-N-H-A-V-A-N-R-Y-A-V-A-L-F-E-L-A-Q-E-K-G-L-H-E-S-F-V-S-E-L-E-L-I-K-A-V-F-Q-D-T-P-E-L-M-Q-F-L-T-H-P-K-T-E-L-T-Q-K-R-E-L-L-E-K-T-F-K-G-K-V-N-D-T-I-F-N-T-L-V-V-L-V-E-R-K-R-I-D-L-I-I-P-V-V-Q-K-F-K-S-L-S-Y-D-A-Q-K-I-A-E-A-F-V-Y-S-A-K-P-L-S-E-A-E-K-D-Q-L-S-V-L-F-A-K-K-V-G-K-A-K-L-L-I-E-N-I-V-D-P-S-I-I-G-G-L-K-I-R-I-G-D-R-I-Y-D-G-S-I-K-G-Q-L-D-V-L-H-R-E-L-V-S-G-P-R-S"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-P-T-L-H-V-N-V-V-T-P-D-G-K-V-Y-E-G-D-V-D-M-V-S-V-K-T-V-E-G-E-L-G-I-L-P-R-H-I-P-L-V-A-P-L-T-V-G-A-V-R-L-K-K-G-S-T-V-D-L-V-A-V-S-G-G-F-V-E-V-R-P-D-Q-V-T-I-L-A-E-A-A-E-L-P-S-D-I-D-V-E-R-A-R-S-A-K-E-R-A-E-K-R-L-Q-Q-A-K-Q-E-N-I-D-F-K-R-A-E-L-S-L-R-R-A-T-N-R-L-D-V-A-G-R"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-K-V-I-E-T-K-Y-N-G-K-L-E-V-A-E-D-R-L-I-A-F-D-Q-G-I-P-A-F-E-D-E-K-E-F-V-L-L-P-F-E-E-G-T-P-Y-Y-T-L-Q-S-T-K-T-V-D-L-A-F-I-I-V-N-P-F-S-F-F-P-E-Y-R-V-K-L-P-E-A-T-I-V-Q-L-N-I-T-N-E-N-D-V-A-I-F-S-L-L-T-V-K-E-P-F-S-E-T-T-V-N-L-Q-A-P-I-V-I-N-A-N-K-Q-M-G-K-Q-L-V-L-G-D-T-A-Y-D-R-K-Q-P-L-F-Q-K-E-L-V-L-A-K-E-A-K"} +{"text": "### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-V-L-S-R-K-S-N-E-S-I-Q-I-G-D-N-I-E-I-S-I-I-S-I-D-G-D-Q-V-K-L-G-I-N-A-P-R-H-I-D-I-H-R-K-E-V-Y-L-A-I-Q-Q-E-N-S-E-A-A-K-T-V-P-L-S-Q-L-K-G-L-L-N-Q-Q-G"} +{"text": "### FUNCTION May act as an export chaperone for the filament capping protein FliD ### SEQUENCE -M-S-S-L-E-Q-L-S-Q-L-T-N-D-L-Y-A-K-V-H-A-P-L-D-S-N-H-D-L-R-E-K-Q-M-E-N-I-E-Q-L-L-K-E-R-A-L-V-M-E-M-G-L-E-R-P-K-D-Q-K-S-K-Q-I-V-R-E-I-L-M-K-S-Q-A-I-Q-E-K-L-A-E-M-S-G-M-I-H-Q-E-I-N-Q-F-K-Q-K-K-Q-M-N-R-K-Y-D-L-P-Y-D-G-P-T-V-E-G-V-F-F-D-K-R-E"} +{"text": "### FUNCTION Involved in carbon catabolite repression ### SEQUENCE -M-V-E-K-Q-V-E-V-K-L-K-T-G-L-Q-A-R-P-A-A-L-F-V-Q-E-A-N-R-F-T-S-E-I-F-I-E-K-D-G-K-K-V-N-A-K-S-I-M-G-L-M-S-L-A-I-G-S-G-S-T-I-T-L-I-T-E-G-N-D-E-Q-E-A-M-E-A-L-I-A-F-I-E-K-E"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-G-E-T-E-G-K-V-I-A-Q-N-K-K-A-R-H-D-Y-F-I-E-E-T-F-E-A-G-M-V-L-Q-G-T-E-I-K-S-I-R-A-G-R-A-N-L-K-D-S-F-A-R-V-S-N-G-E-V-Y-L-H-N-C-H-I-S-E-Y-E-Q-G-N-R-Y-N-H-E-P-T-R-A-R-K-L-L-L-H-K-K-Q-I-D-T-L-I-G-Q-T-Q-Q-K-G-Y-T-I-V-P-L-K-I-Y-I-K-N-G-F-A-K-C-L-I-G-L-G-K-G-K-K-T-F-D-K-R-E-T-L-R-R-R-D-A-K-R-E-V-E-R-A-L-K-E-K-N-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-L-P-N-E-L-K-Y-S-E-E-H-E-W-V-K-V-E-G-D-K-V-R-I-G-I-T-D-F-A-Q-S-E-L-G-D-I-V-F-V-E-L-P-E-V-G-D-E-V-E-A-D-E-P-F-G-S-V-E-S-V-K-T-V-S-E-L-Y-A-P-V-S-G-K-V-V-E-V-N-E-E-L-D-D-N-P-E-Y-V-N-E-S-P-Y-E-K-A-W-M-I-V-V-E-P-S-D-A-S-Q-V-E-E-L-M-S-A-D-E-Y-K-E-M-I-S-E-E"} +{"text": "### FUNCTION May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor ### SEQUENCE -M-L-E-R-L-A-L-T-L-A-H-Q-V-K-A-L-N-A-E-E-T-E-S-V-E-V-L-T-F-G-F-T-I-I-L-H-Y-L-F-T-L-L-L-V-L-A-V-G-L-L-H-G-E-I-W-L-F-L-Q-I-A-L-S-F-T-F-M-R-V-L-T-G-G-A-H-L-D-H-S-I-G-C-T-L-L-S-V-L-F-I-T-A-I-S-W-V-P-F-A-N-N-Y-A-W-I-L-Y-G-I-S-G-G-L-L-I-W-K-Y-A-P-Y-Y-E-A-H-Q-V-V-H-T-E-H-W-E-R-R-K-K-R-I-A-Y-I-L-I-V-L-F-I-I-L-A-M-L-M-S-T-Q-G-L-V-L-G-V-L-L-Q-G-V-L-L-T-P-I-G-L-K-V-T-R-Q-L-N-R-F-I-L-K-G-G-E-T-N-E-E-N-S"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-E-L-I-H-Q-V-A-E-R-T-Q-M-S-K-K-D-A-G-E-V-V-N-T-V-F-D-V-I-A-E-S-L-A-Q-G-D-S-V-Q-L-I-G-F-G-N-F-E-V-R-E-R-A-A-R-K-G-R-N-P-Q-T-G-E-E-I-D-I-A-A-T-K-T-P-A-F-K-A-G-K-Q-L-K-D-A-V-K"} +{"text": "### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-T-V-E-S-F-E-L-D-H-T-I-V-K-A-P-F-V-R-P-C-G-T-H-K-V-G-T-N-G-E-V-N-K-F-D-I-R-F-F-Q-P-N-K-Q-A-M-K-P-D-V-I-H-T-L-E-H-L-L-A-L-N-I-R-K-F-A-E-A-Y-D-H-F-D-V-I-D-L-S-P-M-G-C-Q-T-G-F-Y-L-I-M-S-G-K-P-T-V-E-E-I-I-D-V-L-E-Q-T-M-K-Y-S-L-E-L-E-E-V-P-A-A-N-E-K-Q-C-G-Q-A-K-L-H-D-L-D-G-A-K-K-L-M-T-Y-W-L-S-H-E-K-D-S-L-T-K-V-F-E-S"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-R-Y-T-G-P-T-W-K-I-S-R-R-L-G-I-S-L-S-G-T-G-K-E-L-Q-K-R-P-Y-A-P-G-Q-H-G-P-N-Q-R-K-K-L-S-E-Y-G-L-Q-L-Q-E-K-Q-K-L-R-H-M-Y-G-V-N-E-R-Q-F-R-R-I-F-N-D-A-G-K-M-A-G-I-H-G-E-N-F-M-I-L-L-E-S-R-L-D-N-L-V-Y-R-M-G-L-A-R-T-R-R-A-A-R-Q-L-V-N-H-G-H-I-T-V-D-G-Q-R-V-D-I-P-S-Y-R-V-K-P-G-Q-V-I-G-V-R-E-K-S-R-N-L-Q-V-I-K-E-S-L-E-S-N-D-F-V-P-A-Y-V-T-F-D-A-D-K-L-E-G-T-Y-S-R-F-P-E-R-S-E-L-P-A-E-I-T-E-A-L-I-V-E-F-Y-S-R"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-A-C-H-H-N-G-T-R-V-L-D-S-R-P-A-H-E-G-R-S-I-R-R-R-R-E-C-E-S-C-N-H-R-F-T-T-F-E-M-I-E-E-V-P-L-I-V-V-K-K-D-G-T-R-Q-E-F-S-S-D-K-I-L-R-G-L-I-R-A-C-E-K-R-P-V-P-L-E-T-L-E-G-I-V-N-E-V-E-R-E-L-R-G-Q-G-K-N-E-V-D-S-K-E-I-G-E-L-V-M-E-R-L-A-N-V-D-D-V-A-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-I-N-V-F-I-Q-E-L-K-E-L-M-E-R-D-D-R"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-K-D-M-L-V-N-E-G-I-R-A-R-E-V-R-L-I-G-A-N-G-D-Q-I-G-V-K-S-K-A-E-A-L-D-M-A-R-N-V-N-L-D-L-V-C-V-A-P-N-A-K-P-P-V-C-R-I-M-D-Y-G-K-Y-R-Y-E-Q-Q-K-K-D-K-E-A-R-K-K-Q-K-T-I-N-V-K-E-V-R-L-S-P-T-I-E-D-H-D-F-N-T-K-L-R-N-A-R-K-F-L-S-K-G-D-K-V-K-A-A-I-R-F-R-G-R-A-I-T-H-S-E-I-G-R-N-V-L-E-R-L-A-K-E-C-E-D-I-A-I-V-E-A-K-P-K-M-E-G-R-S-M-F-L-V-L-A-P-K-T-D-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-G-G-Y-V-A-R-R-R-R-K-K-V-L-K-L-A-K-G-Y-F-G-S-K-H-T-L-F-K-S-A-Q-G-Q-V-M-K-S-L-Q-Y-A-Y-R-D-R-R-Q-K-K-R-D-F-R-K-L-W-I-T-R-I-N-A-A-A-R-L-N-G-L-S-Y-S-R-L-M-H-G-L-K-L-A-G-I-N-V-N-R-K-M-L-A-D-L-A-I-N-D-E-K-A-F-A-Q-L-A-E-K-A-K-A-S-L-N-N"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-G-Y-V-P-Y-V-I-E-Q-S-G-L-S-E-R-S-Y-D-I-Y-S-R-L-L-K-D-R-I-V-F-L-G-A-A-I-D-D-Q-I-A-N-S-I-V-A-Q-L-L-F-L-E-A-E-N-P-K-K-D-I-Y-L-Y-I-N-S-P-G-G-S-T-S-A-G-F-A-I-Y-D-T-M-Q-F-V-K-P-S-I-H-T-I-C-T-G-M-A-A-S-F-A-A-I-L-L-L-A-G-T-K-G-K-R-F-A-L-P-N-S-E-I-M-I-H-Q-P-S-G-G-A-Q-G-Q-A-S-D-L-A-I-T-A-K-R-I-L-G-I-R-E-K-L-V-T-V-T-S-E-R-T-G-Q-S-P-E-K-V-A-K-D-M-D-R-D-Y-F-M-S-A-E-E-A-L-E-Y-G-I-V-D-Q-I-I-T-S-V"} +{"text": "### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-K-E-R-Q-R-E-K-Q-R-T-T-V-S-I-Y-G-Q-Q-Y-T-V-A-G-Y-D-S-P-E-Y-M-K-E-V-A-A-E-I-D-A-K-M-R-E-L-R-K-V-N-P-Y-L-D-T-T-R-L-A-V-L-T-A-V-N-V-M-D-D-L-K-K-L-E-E-Y-I-R-Y-L-E-Q-Q-R-L-T-G-D-E-K-N-A"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-A-E-K-T-F-T-I-T-A-E-T-G-I-H-A-R-P-A-T-Q-L-V-N-K-A-G-Q-Y-S-S-E-I-T-L-E-Y-K-G-K-A-V-N-L-K-S-I-M-G-V-M-S-L-G-V-G-K-G-A-Q-V-T-I-K-A-E-G-S-D-E-A-E-A-L-K-G-I-E-E-V-I-K-E-G-L-G-E"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-P-L-K-T-H-T-G-T-I-A-V-L-D-R-V-N-V-D-T-D-Q-I-I-P-K-Q-F-L-K-R-V-E-R-T-G-F-G-Q-F-L-F-F-D-W-R-F-L-P-N-G-E-D-N-P-D-F-E-L-N-Q-P-H-A-K-Q-G-T-I-L-V-A-G-H-N-F-G-C-G-S-S-R-E-H-A-P-W-A-I-K-D-Y-G-F-R-V-V-I-A-P-S-F-A-D-I-F-Y-N-N-C-F-K-N-G-I-L-P-V-K-L-K-Q-E-E-V-T-A-L-M-E-K-G-K-D-T-A-Y-S-L-T-V-N-L-E-A-Q-T-V-T-S-E-D-G-F-E-A-T-F-E-I-D-G-Y-W-K-E-M-L-I-N-G-W-D-E-I-G-L-T-L-R-Y-E-E-Q-I-K-Q-F-E-A-S-R-V"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-K-V-T-K-A-E-L-D-C-V-A-V-K-P-E-Q-Y-P-N-S-P-L-P-E-V-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-K-M-I-N-R-K-K-L-A-R-T-S-Q-R-P-G-K-T-Q-T-L-N-F-Y-N-I-N-D-I-L-H-F-V-D-V-P-G-Y-G-F-A-K-V-S-K-K-D-R-E-A-W-G-R-M-I-E-T-Y-L-Q-Q-R-G-Q-L-K-A-V-L-Q-I-I-D-I-R-H-D-P-T-K-D-D-Q-L-M-Y-D-W-L-K-H-F-E-I-P-V-I-I-I-A-T-K-C-D-K-I-P-K-G-K-W-P-K-H-V-K-N-I-A-S-V-L-E-K-D-G-G-D-P-I-V-I-F-S-S-E-T-G-V-G-K-D-E-A-W-K-A-I-L-H-A-I-S"} +{"text": "### FUNCTION May be involved in the biosynthesis of molybdopterin ### SEQUENCE -M-S-V-E-Q-H-R-K-E-A-P-K-T-V-R-C-M-I-L-T-I-S-D-T-R-T-Y-D-T-D-K-S-G-A-L-I-R-E-L-L-E-A-K-G-H-Q-V-T-E-Y-Q-I-V-K-D-E-Y-S-Q-I-Q-H-W-L-K-V-A-A-G-R-A-D-I-D-A-I-L-L-N-G-G-T-G-I-A-L-R-D-T-T-Y-E-A-V-R-D-S-L-D-K-E-M-P-G-F-G-E-I-F-R-L-L-S-F-Q-E-D-I-G-T-A-A-I-L-S-R-A-I-A-G-V-R-D-G-K-A-I-F-S-M-P-G-S-T-G-A-V-K-L-A-M-T-R-I-I-I-P-E-L-G-H-V-M-R-E-I-L-K-D-R"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-E-T-G-G-K-Q-V-K-V-E-E-G-Q-E-I-Y-I-E-K-L-D-A-E-A-G-E-S-V-N-F-D-K-V-V-L-V-G-G-D-D-V-K-V-G-S-P-Y-V-E-G-A-S-V-T-A-K-V-E-K-H-G-R-G-K-K-I-I-V-F-K-M-K-A-K-K-N-Y-R-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-E-K-I-N-A"} +{"text": "### FUNCTION Catalyzes the reduction of arsenate ### SEQUENCE -M-N-K-K-V-I-Y-F-L-C-T-G-N-S-C-R-S-Q-M-A-E-G-W-G-K-K-Y-L-G-D-E-W-D-V-Y-S-A-G-I-E-A-H-G-V-N-P-N-A-V-K-A-M-K-E-I-G-I-D-I-S-E-Q-T-S-D-T-I-D-Q-E-L-L-Q-K-A-D-L-V-V-T-L-C-G-H-A-A-D-V-C-P-A-T-P-S-N-K-E-R-V-H-W-G-F-D-D-P-A-K-A-E-G-T-D-E-E-K-W-A-V-F-R-R-V-R-D-E-I-G-K-R-I-K-T-F-A-E-T-G-K"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-R-Q-T-V-K-E-I-V-A-I-G-I-G-G-A-I-G-T-S-F-R-F-L-L-N-T-W-T-L-T-T-G-Y-P-Y-G-T-L-I-E-N-I-V-G-S-F-L-L-G-F-L-T-S-W-F-L-V-I-V-P-K-E-W-L-K-K-G-L-G-V-G-L-C-G-G-F-T-T-M-S-T-L-A-A-D-S-V-L-L-Y-S-H-H-P-F-S-S-L-I-Y-V-A-A-S-L-F-G-G-I-G-F-A-L-L-G-Y-L-L-A-S-K-I-A-T-R-R-K-R-E-V-A-G-S"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-L-L-I-V-A-I-G-G-G-I-G-A-I-A-R-Y-L-V-G-Q-W-M-M-K-R-F-P-D-P-P-F-P-I-A-M-L-V-V-N-L-L-G-S-F-G-L-G-A-F-F-G-L-Y-Y-H-E-L-F-A-A-S-Y-D-D-I-G-Y-L-F-G-G-I-G-F-F-G-A-F-T-T-Y-S-T-F-S-V-E-A-V-L-L-I-R-E-R-E-W-K-K-L-F-S-Y-V-L-L-S-I-V-G-S-I-A-A-F-L-L-G-F-Y-G-T-S-S-W"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-T-L-L-T-S-P-S-C-T-S-C-R-K-A-K-A-W-L-E-E-H-N-I-P-F-E-E-R-N-I-F-S-S-P-L-T-V-E-E-V-K-E-V-V-R-M-T-E-D-G-T-D-E-I-I-S-T-R-S-K-V-F-Q-E-L-D-V-E-L-E-A-L-P-L-Q-T-L-F-K-I-I-S-E-N-P-G-L-L-R-R-P-I-I-F-D-E-K-R-L-Q-V-G-Y-N-E-A-E-I-R-R-F-L-P-R-K-V-R-T-F-Q-L-Q-E-A-Q-R-L-V-N"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-V-N-D-F-K-T-G-L-T-I-E-V-D-N-G-I-W-Q-V-M-E-F-Q-H-V-K-P-G-K-G-A-A-F-V-R-S-K-L-R-N-L-R-T-G-A-V-Q-E-K-T-F-R-A-G-E-K-V-S-K-A-H-I-E-N-R-R-M-Q-Y-L-Y-A-S-G-D-V-H-T-F-M-D-N-E-T-F-E-Q-L-E-L-S-T-A-Q-I-E-H-E-L-K-F-L-K-E-N-M-E-V-H-V-I-S-Y-Q-G-E-T-L-G-V-E-V-P-N-T-V-E-L-T-V-T-E-T-E-P-G-I-K-G-D-T-A-S-G-G-T-K-P-A-T-L-E-T-G-L-T-V-Q-V-P-F-F-V-N-E-G-D-V-L-V-I-D-T-R-S-G-D-Y-V-S-R-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-N-R-R-L-S-R-L-R-A-V-Q-A-L-Y-Q-M-D-V-I-D-T-S-M-E-K-A-I-E-S-V-L-D-E-G-E-E-A-S-S-F-M-S-D-L-V-S-G-T-V-T-H-Q-E-E-L-D-R-L-Y-A-D-H-L-Q-G-W-T-V-D-R-I-G-N-V-D-R-A-I-L-R-M-A-L-Y-E-L-Y-Y-V-D-D-I-P-K-N-V-S-F-N-E-A-I-E-L-A-K-A-F-G-G-E-D-A-G-R-F-I-N-G-V-L-S-K-T-M-E-A-Y-K-P-K-D-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-I-K-N-E-Q-P-P-L-S-F-E-E-A-M-E-Q-L-E-E-V-V-E-Q-L-E-Q-G-D-V-P-L-E-E-A-I-S-M-F-Q-K-G-M-N-L-S-K-V-C-H-E-K-L-A-T-V-E-K-Q-M-D-Q-I-L-K-E-D-G-N-F-E-E-T-V-L-Q-E-E-Q-E"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-G-Q-R-H-I-K-I-R-E-I-I-A-N-N-D-V-E-T-Q-D-E-L-V-E-Q-L-K-A-A-G-Y-N-V-T-Q-A-T-V-S-R-D-I-K-E-L-H-L-V-K-V-P-M-M-D-G-R-Y-K-Y-S-L-P-A-D-Q-R-F-N-P-L-Q-K-L-K-R-G-L-V-D-S-F-V-S-I-D-R-T-D-N-L-I-V-M-K-T-L-P-G-N-A-H-A-I-G-A-L-I-D-N-L-D-W-T-E-I-M-G-T-I-C-G-D-D-T-I-L-I-I-C-K-D-K-Q-D-G-P-V-V-T-E-R-F-L-N-M-L"} +{"text": "### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-I-F-Y-Q-K-D-F-D-Q-V-P-V-R-E-N-T-D-S-L-Y-V-E-A-E-S-E-A-D-V-R-K-K-L-S-E-K-N-Y-N-L-E-F-I-T-P-I-S-G-E-F-L-A-Y-E-Q-Q-K-E-H-F-T-V-E-K-L"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-L-T-M-K-D-I-V-R-E-G-N-P-V-L-R-E-V-A-K-P-V-P-V-P-L-S-D-E-D-K-Q-T-A-K-R-M-L-E-F-L-I-N-S-Q-N-P-E-I-A-E-K-Y-S-L-R-P-G-V-G-L-A-A-P-Q-I-G-L-S-K-Q-M-I-A-V-H-T-T-D-E-N-E-K-E-Y-S-L-V-L-F-N-P-K-I-I-S-E-S-V-E-M-T-H-L-E-G-G-E-G-C-L-S-V-D-R-E-V-Q-G-I-V-P-R-H-A-R-I-T-V-K-A-I-N-E-N-N-E-E-V-R-L-K-L-K-G-F-P-A-I-V-F-Q-H-E-I-D-H-L-N-G-I-M-F-Y-D-R-I-E-G-W-V-D-P-Y-K-R-E-I-N-P-S-L"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-G-M-K-S-K-F-K-R-F-F-E-L-D-D-D-A-S-M-Y-E-E-D-A-V-S-R-D-F-V-E-E-V-E-E-P-R-R-R-S-R-T-G-V-K-Q-E-R-E-T-G-Q-N-V-V-S-L-Q-S-V-Q-K-T-A-K-V-V-L-L-E-P-R-T-Y-D-E-A-Q-E-I-A-D-Q-L-K-N-R-K-A-V-I-I-N-L-Q-R-I-S-H-E-Q-A-K-R-V-V-D-F-L-S-G-T-V-Y-A-I-G-G-D-I-Q-K-L-G-M-N-I-F-L-C-T-P-D-N-V-D-V-T-G-T-I-T-D-M-I-Q-D-G-Y-R-S"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-S-R-L-I-L-D-E-Q-A-I-R-R-A-T-T-R-I-A-H-E-I-I-E-R-N-K-G-V-S-D-C-L-L-V-G-I-K-T-R-G-I-Y-L-A-N-R-L-Q-E-R-I-E-T-I-E-G-I-K-L-P-V-G-E-V-D-I-T-L-Y-R-D-D-L-T-V-K-S-T-T-E-E-P-I-L-Q-G-T-D-V-P-V-D-V-T-G-K-K-V-I-L-I-D-D-V-L-Y-T-G-R-T-V-R-A-A-L-D-A-L-M-D-L-G-R-P-E-Q-I-Q-L-A-V-L-I-D-R-G-H-R-E-L-P-I-R-P-D-Y-V-G-K-N-V-P-T-S-K-Q-E-Q-I-V-A-K-L-S-E-V-D-G-I-D-E-V-T-I-E-Q-K-T-S"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-L-Y-P-S-I-D-S-L-M-D-K-L-D-S-K-Y-T-L-V-T-V-S-A-K-R-A-R-E-L-K-E-D-D-Q-R-G-P-L-V-G-K-P-K-S-F-K-P-V-G-V-A-L-E-E-I-V-E-D-H-L-Q-Y-E-R-K-E-Q"} +{"text": "### FUNCTION Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism ### SEQUENCE -M-K-R-K-K-Q-D-R-Q-R-H-L-K-E-T-I-D-A-N-P-F-I-T-D-E-A-L-A-D-R-F-G-V-S-I-Q-T-I-R-L-D-R-M-E-L-S-I-P-E-L-R-E-R-I-K-D-V-A-Q-K-Q-L-D-E-V-K-A-L-P-M-E-E-V-F-G-E-I-V-D-L-Q-L-D-E-R-A-I-S-I-L-D-V-K-K-E-H-V-F-S-R-T-G-I-A-R-G-H-Y-L-F-A-Q-A-N-S-L-A-V-A-I-I-D-D-D-L-A-L-T-A-K-A-T-I-R-F-T-R-Q-V-K-A-G-E-R-V-V-A-K-A-E-V-Q-K-V-E-R-D-R-T-L-V-V-V-N-S-F-V-E-Q-E-L-V-F-S-G-D-F-L-M-Y-R-S-A-Q-E-Q"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-D-T-L-S-R-I-T-K-I-V-V-D-R-L-G-V-D-E-A-E-V-K-P-E-A-S-F-K-D-D-L-G-A-D-S-L-D-V-V-E-L-V-M-E-L-E-D-E-F-D-L-E-I-S-D-E-E-A-E-K-I-A-T-V-A-D-V-V-E-Y-I-E-G-R-Q"} +{"text": "### FUNCTION A probable RNA chaperone Forms a complex with KhpB which binds to cellular RNA and controls its expression Plays a role in peptidoglycan homeostasis and cell length regulation ### SEQUENCE -M-K-T-L-V-E-H-I-A-M-A-L-V-D-H-P-D-D-V-R-V-S-E-H-D-D-G-H-S-L-H-I-E-L-S-V-H-P-D-D-M-G-K-V-I-G-K-Q-G-R-T-A-K-A-L-R-S-V-V-Y-A-A-A-T-K-Q-K-R-R-V-R-L-D-I-I-D"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-K-W-L-N-V-G-K-I-V-N-T-H-G-V-R-G-E-V-R-V-L-S-T-T-D-F-E-D-D-R-F-S-S-G-K-T-L-Y-V-M-R-P-N-Q-N-E-R-V-A-V-T-V-A-S-H-R-K-H-K-N-F-D-L-L-C-F-E-G-Y-P-S-I-N-D-V-E-A-F-K-G-G-R-L-Q-V-P-I-E-D-R-P-E-L-G-E-G-E-F-F-Y-H-E-I-I-G-C-S-V-V-T-I-A-G-E-E-L-G-K-V-K-E-I-L-S-P-G-A-N-D-V-W-V-V-Q-C-R-R-G-G-K-D-L-L-I-P-Y-I-E-Q-V-V-K-Q-V-D-L-E-K-Q-Q-I-T-I-E-P-M-E-G-L-L-E"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-N-I-I-R-E-I-T-N-E-Q-L-R-T-D-L-P-S-F-R-P-G-D-T-L-R-V-H-V-K-V-I-E-G-S-R-E-R-I-Q-V-F-E-G-V-V-I-K-R-R-G-T-G-V-S-E-T-F-T-V-R-K-I-S-Y-G-V-G-V-E-R-T-F-P-L-H-S-P-K-I-D-K-I-E-V-K-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-N-L-R-G-K-A-A-R-I-K-E-I-R"} +{"text": "### FUNCTION Deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors ### SEQUENCE -M-N-D-V-V-K-V-G-M-A-D-L-N-V-V-T-P-P-H-T-I-R-T-A-G-L-G-S-C-V-G-V-V-L-Y-D-D-V-K-K-V-A-G-M-A-H-I-M-L-P-D-S-A-L-G-K-K-Q-E-F-N-R-A-K-Y-A-D-T-A-L-D-L-L-L-S-K-L-E-A-I-G-A-K-R-Y-S-L-K-A-K-M-A-G-G-A-Q-M-F-S-F-A-S-N-N-D-M-M-R-I-G-Q-R-N-V-E-A-V-K-K-K-L-R-E-L-S-I-P-I-L-A-E-D-V-G-G-S-N-G-R-T-I-E-F-N-P-E-T-K-R-L-S-I-R-T-V-H-Q-G-E-K-E-I"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-K-E-V-L-N-D-A-E-Q-R-M-T-K-A-T-E-A-L-G-R-E-L-A-K-L-R-A-G-R-A-N-P-A-M-L-D-R-I-T-V-E-Y-Y-G-A-E-T-P-L-N-Q-L-A-T-I-S-V-P-E-A-R-L-L-V-I-Q-P-F-D-K-S-S-I-S-D-I-E-R-A-I-Q-K-S-D-L-G-L-T-P-S-N-D-G-T-V-I-R-I-T-I-P-P-L-T-E-E-R-R-R-D-L-T-K-L-V-K-K-S-A-E-E-A-K-V-A-V-R-N-I-R-R-D-A-N-D-D-L-K-K-R-Q-K-D-G-E-L-T-E-D-D-L-R-R-V-T-E-D-V-Q-K-L-T-D-K-Y-I-E-Q-I-D-Q-K-A-E-A-K-E-K-E-I-M-E-V"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-G-K-K-V-V-D-I-T-A-E-L-V-K-P-I-L-E-Q-L-D-L-E-L-Y-D-V-E-F-K-K-E-G-K-D-W-F-L-R-V-F-I-D-S-E-T-G-V-D-L-E-D-C-G-K-V-S-E-R-L-S-E-K-L-D-E-T-D-P-I-E-Q-A-Y-F-L-E-V-S-S-P-G-A-E-R-P-L-K-R-E-K-D-L-L-R-S-I-G-K-N-V-H-V-T-L-Y-E-P-I-D-G-E-K-A-L-E-G-E-L-T-E-F-D-G-E-T-L-T-I-E-I-K-I-K-T-R-K-K-T-V-T-I-P-Y-A-K-V-A-S-A-R-L-A-V-V-F"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-N-V-R-A-N-R-V-G-E-Q-M-K-K-E-L-S-D-I-F-M-R-E-L-K-D-P-R-I-E-F-V-T-V-T-G-V-D-V-T-G-D-L-Q-Q-A-N-V-Y-I-T-V-L-G-D-D-E-Q-K-E-A-T-L-A-G-L-S-K-A-K-G-F-I-R-S-E-I-G-K-R-I-R-L-R-K-T-P-E-L-F-F-H-F-D-E-S-I-E-Y-G-N-R-I-E-K-L-L-Q-D-I-N-R-D-G-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-Q-E-R-K-N-E-I-I-N-E-F-K-T-H-E-N-D-T-G-S-P-E-V-Q-V-A-I-L-T-E-Q-I-N-T-L-N-E-H-L-R-T-H-K-K-D-H-H-S-R-R-G-L-L-K-M-V-G-Q-R-R-N-L-L-T-Y-L-R-N-K-D-V-T-R-Y-R-N-L-V-D-K-L-G-L-R-R"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-K-S-S-V-N-I-Q-D-H-F-L-N-Q-L-R-K-E-N-I-P-V-T-V-F-L-L-N-G-F-Q-L-R-G-L-V-K-G-F-D-N-F-T-V-I-L-E-T-E-G-K-Q-Q-L-V-Y-K-H-A-I-S-T-F-A-P-Q-R-N-V-Q-M-K-T-E-N-E-P-S"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-K-R-L-E-R-A-M-F-A-G-G-C-F-W-C-M-V-Q-P-F-D-K-Q-P-G-I-E-S-V-V-S-G-Y-A-G-G-T-V-E-N-P-T-Y-E-Q-V-K-T-G-T-T-G-H-Y-E-V-V-H-I-T-Y-V-P-E-L-F-P-F-E-K-L-L-S-L-Y-W-P-Q-I-D-P-T-D-P-D-G-Q-F-H-D-R-G-P-Q-Y-R-T-A-I-F-Y-E-N-E-E-Q-R-A-L-A-E-R-S-R-E-A-L-E-K-S-G-K-F-K-K-P-I-V-T-S-I-L-P-M-A-T-F-Y-P-A-E-E-E-H-Q-Q-F-Y-K-K-N-P-M-A-Y-K-E-D-R-E-K-S-G-R-D-E-F-I-Y-K-H-W-G-K"} +{"text": "### FUNCTION Required for proper spore morphogenesis Important for spore germination ### SEQUENCE -M-D-L-F-F-A-Y-M-L-V-A-S-A-T-P-L-F-L-W-L-E-H-R-K-I-A-L-T-S-I-P-F-I-I-I-M-W-V-L-A-L-S-H-M-F-E-G-F-L-F-D-L-H-H-S-V-F-L-T-A-F-F-V-N-V-I-I-A-H-F-A-A-L-V-L-Y-A-Y-P-H-I-R-P-K-S-R-T-F-T-E-S-M-D"} +{"text": "### FUNCTION Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization ### SEQUENCE -M-S-K-H-K-S-H-R-I-G-Q-L-A-I-L-L-A-V-S-E-E-P-G-I-V-E-A-S-I-L-S-S-D-Y-Q-S-C-I-G-R-V-G-S-M-E-S-N-K-I-V-A-A-I-E-T-A-A-K-K-N-G-F-I-R-E-G-V-Y-R-E-A-H-A-L-Y-H-A-I-I-E-A-L-H-G-V-T-R-G-Q-V-Q-L-G-S-F-Q-R-T-V-G-L-R-F-A-I-V-R-G-K-P-Y-K-E-E-A-E-G-E-W-I-A-V-A-L-Y-G-T-I-G-A-P-I-K-G-Q-E-H-E-T-I-G-L-G-I-N-H-I"} +{"text": "### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-S-K-K-V-E-N-L-M-L-G-S-W-L-T-A-L-T-A-M-L-G-S-L-Y-F-S-E-I-R-M-Y-E-P-C-T-L-C-W-Y-Q-R-I-I-M-Y-P-L-V-L-I-L-F-I-G-Y-L-K-R-D-V-N-V-A-L-Y-S-L-W-F-S-L-I-G-M-F-T-S-L-Y-H-Y-S-I-Q-K-L-P-F-L-T-D-A-A-P-A-C-G-R-V-P-C-T-G-Q-Y-I-N-W-F-G-F-V-T-I-P-F-L-A-F-T-A-F-V-I-I-F-I-C-S-L-L-I-I-R-E-K"} +{"text": "### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-Y-N-Q-E-V-K-L-T-T-K-E-I-L-E-K-E-F-K-T-S-M-R-G-Y-S-Q-D-E-V-D-K-F-L-D-V-V-I-Q-D-Y-E-V-F-Q-K-K-I-E-R-L-E-Q-E-I-H-Q-L-R-T-E-A-K-R-A-A-S-E-R-Q-T-R-H-Q-T-S-P-S-V-G-S-T-N-Y-D-I-L-Q-R-L-S-N-L-E-K-K-V-F-G-N-K-L-Y-E"} +{"text": "### FUNCTION Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure ### SEQUENCE -M-A-V-Q-W-K-T-K-E-V-S-E-Q-L-G-V-N-P-T-T-V-Q-R-W-V-K-F-F-G-I-Q-C-E-T-N-E-H-G-H-L-L-F-E-K-E-H-L-T-V-L-K-A-I-Q-N-Q-L-K-S-G-K-K-M-R-D-V-V-I-E-E-N-E-Q-L-I-Q-K-P-E-T-Q-P-M-V-A-T-E-Q-Y-E-Q-R-T-K-Q-F-M-E-K-I-A-E-L-E-K-Q-L-S-Q-K-A-D-D-V-V-S-Y-Q-I-L-K-H-R-A-E-I-D-E-M-F-K-T-L-Q-S-L-E-L-R-M-A-K-V-E-E-Q-L-E-K-Q-Q-E-E-F-P-L-A-A-G-D-V-P-K-R-K-R-S-F-M-R-L-F-S-F"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-R-I-A-L-I-A-H-D-K-K-K-D-E-M-V-Q-F-T-I-A-Y-K-D-V-L-K-D-H-E-L-Y-A-T-G-T-T-G-M-R-I-M-E-A-A-Q-L-P-V-K-R-F-K-S-G-P-L-G-G-D-Q-Q-I-G-A-L-V-A-E-N-K-F-D-L-I-I-F-L-R-D-P-L-T-A-Q-P-H-E-P-D-V-T-A-L-V-R-L-C-D-V-Q-R-V-P-L-A-T-N-I-G-T-A-E-I-L-I-K-G-L-A-R-G-D-F-T-W-R-E-L-V-H-D-E-E-E-P-R-V"} +{"text": "### FUNCTION Required for transcription attenuation control in the Trp operon This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination Binds the leader RNA only in presence of L-tryptophan ### SEQUENCE -M-N-V-G-D-N-S-N-F-F-V-I-K-A-K-E-N-G-V-N-V-F-G-M-T-R-G-T-D-T-R-F-H-H-S-E-K-L-D-K-G-E-V-M-I-A-Q-F-T-E-H-T-S-A-V-K-I-R-G-K-A-I-I-Q-T-S-Y-G-T-L-D-T-E-K-D-E"} +{"text": "### FUNCTION Putative gamma-glutamylcyclotransferase ### SEQUENCE -M-R-G-A-R-C-H-N-R-R-C-Y-V-Y-G-H-L-Y-D-S-G-L-G-Y-P-A-L-I-A-D-E-K-G-G-K-V-V-G-E-L-Y-E-I-N-E-Q-H-L-V-S-L-D-E-L-E-D-Y-A-P-D-R-N-H-N-L-Y-E-R-V-L-H-T-L-E-D-G-S-H-C-Y-L-Y-V-V-T-P-D-S-P-L-V-R-T-L-I-P-S-G-D-W-L-D-W-T-E-N-K-K-S-T-E"} +{"text": "### FUNCTION Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c ### SEQUENCE -M-D-K-R-K-R-F-W-M-R-L-S-I-L-A-V-I-S-V-A-L-G-Y-T-F-Y-S-N-F-F-A-D-R-S-L-A-R-A-G-E-Q-A-V-N-F-V-L-E-D-L-E-G-E-S-I-E-L-R-E-L-E-G-K-G-V-F-L-N-F-W-G-T-Y-C-P-P-C-E-R-E-M-P-H-M-E-K-L-Y-G-E-Y-K-E-Q-G-V-E-I-I-A-V-N-A-N-E-P-E-L-T-V-Q-R-F-V-D-R-Y-G-L-S-F-P-I-V-I-D-K-G-L-N-V-I-D-A-Y-G-I-R-P-L-P-T-T-I-L-I-N-E-H-G-E-I-V-K-V-H-T-G-G-M-T-E-Q-M-V-E-E-F-M-E-L-I-K-P-E-A"} +{"text": "### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-T-L-K-E-L-Q-A-A-I-E-G-I-L-F-V-R-G-D-E-G-V-T-L-E-E-L-C-D-L-L-E-L-S-T-D-V-V-Y-A-A-L-E-E-L-R-L-S-Y-T-D-E-A-R-G-L-R-I-E-E-V-A-H-A-F-R-L-S-T-K-P-E-L-A-P-Y-F-K-K-L-A-L-S-T-L-Q-S-G-L-S-Q-A-A-L-E-T-L-A-I-I-A-Y-R-Q-P-I-T-R-I-E-V-D-E-V-R-G-V-K-S-E-K-A-I-Q-T-L-T-S-R-L-L-I-K-E-V-G-R-A-Q-G-T-G-R-P-I-L-Y-G-T-T-P-Q-F-L-D-H-F-G-L-K-S-L-K-E-L-P-P-L-P-E-D-I-D-E-S-S-I-G-E-E-A-D-L-F-F-Q-Q-M-E-Q-G-S-L-F-H-E-E"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-N-I-Q-I-D-M-I-D-H-T-D-T-L-T-E-K-Q-E-T-L-I-R-E-L-L-H-E-A-A-R-Y-E-K-L-A-E-G-T-Y-E-L-S-L-S-F-V-S-D-E-E-I-Q-E-L-N-R-D-Y-R-G-K-D-Q-P-T-D-V-I-S-F-A-L-N-E-V-G-E-G-E-Q-P-V-E-P-E-A-G-T-P-N-L-L-G-D-I-I-V-S-I-P-R-C-Q-E-Q-A-E-A-Y-G-H-S-F-E-R-E-L-A-F-L-I-V-H-G-F-L-H-L-L-G-Y-D-H-M-S-E-D-E-E-K-K-M-F-M-R-Q-E-D-I-L-T-A-Y-G-L-T-R-S"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-V-E-N-E-K-T-S-V-E-E-T-E-E-K-A-E-T-E-D-E-M-L-T-E-D-P-S-N-E-D-S-D-E-A-N-E-E-G-N-E-L-S-E-E-E-K-R-I-A-E-L-E-G-Q-V-D-E-L-N-Q-R-L-L-R-I-Q-A-D-Y-D-N-F-R-R-R-Q-R-E-E-K-E-A-A-A-K-Y-R-A-Q-S-L-I-E-E-L-L-P-A-L-D-N-F-E-R-A-L-L-V-E-P-E-Q-E-E-T-K-T-L-L-K-G-M-E-M-V-Y-R-Q-V-S-E-A-L-K-K-E-G-L-E-V-I-E-T-K-G-E-T-F-D-P-H-L-H-Q-A-V-M-Q-V-E-D-A-E-F-E-S-N-E-I-V-E-E-L-Q-K-G-Y-K-L-K-D-R-V-I-R-P-S-M-V-K-V-N-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-K-G-N-A-N-I-K-S-A-I-K-R-V-K-T-N-E-K-R-R-I-Q-N-A-S-V-K-S-A-L-R-T-A-I-K-Q-F-E-A-K-V-E-N-N-D-A-E-A-A-K-A-A-F-V-E-A-T-K-K-L-D-K-A-A-N-K-G-L-I-H-K-N-A-A-S-R-Q-K-S-R-L-A-K-K-L-N-G-L-S-A"} +{"text": "### FUNCTION Functions as a ribosomal silencing factor Interacts with ribosomal protein uL14 , blocking formation of intersubunit bridge B8 Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation ### SEQUENCE -M-S-N-Q-E-L-L-Q-L-A-V-N-A-V-D-D-K-K-A-E-Q-V-V-A-L-N-M-K-G-I-S-L-I-A-D-F-F-L-I-C-H-G-N-S-E-K-Q-V-Q-A-I-A-H-E-L-K-K-V-A-Q-E-Q-G-I-E-I-K-R-L-E-G-Y-E-Q-A-R-W-V-L-I-D-L-G-D-V-V-V-H-V-F-H-K-D-E-R-A-Y-Y-N-L-E-K-L-W-G-D-A-P-T-V-E-L-E-G-V-I-S"} +{"text": "### FUNCTION Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP ### SEQUENCE -M-N-R-G-K-A-L-Q-L-V-K-P-H-L-T-E-H-R-Y-Q-H-T-I-G-V-M-E-T-A-I-D-L-A-K-L-Y-G-A-D-Q-Q-K-A-E-L-A-A-I-F-H-D-Y-A-K-F-R-D-K-N-E-M-R-T-L-I-R-E-K-L-S-Q-Q-D-I-L-F-Y-G-D-E-L-L-H-A-P-C-G-A-Y-Y-V-R-E-E-V-G-I-E-D-E-D-V-L-Q-A-I-R-F-H-T-T-G-R-P-N-M-S-L-L-E-K-I-I-F-L-A-D-Y-I-E-P-N-R-Q-F-P-G-V-E-K-V-R-T-Q-A-K-T-D-L-N-G-A-I-I-S-S-L-V-N-T-I-T-F-L-L-K-K-N-Q-P-I-Y-P-D-T-L-A-T-Y-N-Q-L-L-L-E-Q-K"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-D-L-I-N-A-V-A-E-Q-A-E-L-S-K-K-D-A-S-K-A-V-D-A-V-F-E-S-I-T-G-A-L-K-E-G-G-K-V-Q-L-V-G-F-G-S-F-E-V-R-E-R-S-A-R-K-G-R-N-P-Q-T-G-E-E-I-E-I-P-A-T-K-N-P-A-F-K-P-G-K-Q-L-K-D-A-V-N"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-E-E-K-K-H-Y-M-T-L-E-G-K-K-K-L-E-E-E-L-E-Y-L-K-T-E-R-R-K-E-V-V-E-R-I-K-I-A-R-S-F-G-D-L-S-E-N-S-E-Y-D-S-A-K-E-E-Q-A-F-V-E-G-R-I-S-Q-I-E-K-M-I-R-N-A-E-I-I-E-E-S-E-G-D-A-N-V-V-S-L-G-K-T-V-K-F-V-E-I-P-D-G-E-E-E-E-Y-T-I-V-G-S-A-E-S-D-P-F-E-G-K-I-S-N-D-S-P-M-A-Q-S-L-L-G-H-T-I-D-D-V-V-I-V-N-T-P-G-G-E-M-E-V-K-I-L-E-I-R"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-T-L-G-L-D-V-G-T-K-T-I-G-I-A-V-S-D-A-L-G-W-T-A-Q-G-L-E-T-W-R-R-S-D-A-N-E-Q-A-D-F-E-H-I-A-S-L-V-K-E-H-E-V-T-T-I-V-I-G-L-P-K-N-M-D-G-S-I-G-P-S-G-E-R-S-E-T-F-A-A-E-L-R-R-Y-V-P-C-E-I-V-M-W-D-E-R-L-T-T-T-A-A-E-R-M-L-I-S-A-D-V-S-R-K-K-R-K-S-V-I-D-K-M-A-A-V-M-I-L-Q-G-Y-L-D-R-Q-Q-L-K"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-F-K-Q-H-I-T-I-V-E-N-F-P-K-E-G-I-R-F-K-D-I-T-T-L-M-Q-N-G-E-V-Y-K-R-A-I-D-E-M-A-R-F-A-K-E-K-E-V-D-L-V-V-G-P-E-A-R-G-F-V-V-G-C-P-I-A-Y-A-I-G-K-G-F-V-P-V-R-K-A-G-K-L-P-R-E-V-I-S-V-D-Y-G-L-E-Y-G-K-D-R-L-T-I-H-R-D-A-I-Q-K-G-Q-R-V-L-I-A-D-D-L-L-A-T-G-G-T-I-E-A-T-V-Q-M-V-E-Q-L-G-G-E-V-V-G-I-A-F-M-I-E-L-G-Y-L-N-G-R-D-K-L-V-T-Y-D-V-F-S-L-T-T-Y-E"} +{"text": "### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-E-G-L-G-G-F-L-I-P-L-I-L-M-F-A-I-F-Y-F-L-L-I-R-P-Q-Q-K-R-Q-K-Q-I-Q-E-M-H-N-N-L-Q-R-G-D-K-I-V-T-I-G-G-L-H-G-T-I-D-S-L-D-E-S-T-V-V-I-L-V-N-D-N-R-K-L-T-F-D-R-S-A-I-R-E-V-V-N-P-D"} +{"text": "### FUNCTION Negative regulator of protease production and sporulation ### SEQUENCE -M-E-Q-Q-T-A-Y-S-L-K-Q-S-I-I-F-S-H-K-F-A-Q-L-S-K-A-L-W-K-S-V-E-K-D-W-Q-T-W-I-K-P-F-N-L-N-I-N-E-H-H-I-L-W-I-T-Y-H-L-D-G-A-S-I-S-D-I-A-K-F-G-V-M-H-V-S-T-A-F-N-F-S-K-K-L-E-E-R-G-L-L-T-F-S-K-R-E-H-D-K-R-N-T-Y-V-D-L-T-E-Q-G-R-E-L-F-L-E-T-L-E-A-Y-K-P-S-T-Y-S-V-Y-G-G-A-L-P-I-K-D-L-Y-G-K-F-P-E-F-S-E-L-L-S-I-V-R-H-V-Y-G-P-D-F-I-D-M-F-E-T-A-L-T-R-L-E-D-G-F-I-E-E-D-G-K-L-K-A-V-D-S-E-T-K-S-T-V"} +{"text": "### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate with acetyl coenzyme A ### SEQUENCE -M-Q-V-Q-C-N-E-K-A-F-K-G-G-F-I-I-N-S-Q-I-A-T-A-P-P-K-T-L-D-T-T-I-T-I-G-K-P-T-V-E-D-G-A-A-M-W-E-L-V-N-K-S-T-L-D-T-N-S-P-Y-K-Y-I-M-M-C-E-Y-F-A-E-T-C-V-V-A-K-E-N-E-R-L-V-G-F-V-T-A-F-I-P-P-E-H-Q-D-V-I-F-V-W-Q-I-G-V-D-S-S-Q-R-G-K-G-L-A-S-K-L-L-Q-E-L-I-S-R-D-I-C-S-N-V-N-Y-V-E-A-T-V-T-P-S-N-K-A-S-Q-A-L-F-Q-K-L-A-R-E-Y-N-T-Q-C-E-V-S-E-C-F-S-E-D-L-F-P-G-D-D-H-E-A-E-L-T-F-R-I-G-P-L-H-P"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-K-V-V-K-L-E-D-V-I-G-T-E-Q-E-V-K-G-E-N-W-T-S-R-R-L-L-L-K-K-D-G-M-G-Y-S-V-H-D-T-I-I-K-A-G-T-E-T-H-I-W-Y-Q-N-H-L-E-A-V-Y-C-I-E-G-E-G-E-V-E-T-V-K-D-G-K-V-W-P-I-K-A-N-E-I-Y-A-L-D-E-H-D-E-H-L-L-R-A-K-T-D-M-R-M-V-C-V-F-N-P-P-I-T-G-K-E-T-H-D-E-N-G-V-Y-P-L-V-D-D-E"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 5-hydroxyisourate ### SEQUENCE -M-S-G-K-V-T-T-H-V-L-D-T-S-C-G-K-P-A-A-G-V-V-V-E-L-W-R-I-V-E-G-G-E-S-E-L-L-T-K-A-V-T-N-Q-D-G-R-L-D-K-P-L-L-T-E-N-K-M-A-R-G-V-Y-E-L-R-F-Q-V-G-D-Y-F-L-R-N-G-F-V-N-Q-A-Y-P-F-L-H-V-I-P-V-R-F-G-L-E-D-V-N-E-H-Y-H-V-P-L-L-V-A-P-G-G-Y-S-T-Y-R-G-S"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-R-I-S-M-E-Q-V-K-H-V-A-H-L-A-R-L-A-I-T-E-E-E-A-K-L-F-T-E-Q-L-G-D-I-I-Q-F-A-E-Q-L-N-E-L-D-T-E-G-V-E-P-T-S-H-V-L-D-M-K-N-V-L-R-E-D-K-P-E-K-G-L-P-V-E-D-V-L-K-N-A-P-D-H-E-D-G-Q-I-R-V-P-S-V-L-E"} +{"text": "### FUNCTION Negative regulator of sigma-B activity Phosphorylates and inactivates its specific antagonist protein, RsbV Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme ### SEQUENCE -M-R-V-H-Q-P-E-T-I-E-M-T-V-P-A-K-S-E-F-V-G-V-V-R-L-T-V-S-G-I-A-N-R-L-G-Y-T-Y-D-D-I-E-D-I-K-I-A-V-A-E-A-C-T-N-V-V-D-H-A-Y-D-E-G-G-T-M-G-L-S-F-H-L-Y-E-D-R-M-E-I-I-V-T-D-Q-G-Q-S-F-D-M-D-A-F-R-E-S-L-G-P-I-D-G-S-K-P-I-Q-D-L-K-E-G-G-L-G-L-F-L-I-N-T-L-M-D-K-V-E-M-K-E-D-S-G-V-V-L-A-M-T-K-F-L-Q-R-D-E-V-D-N-R-V-D-G-I-S-A-T-Q-T-E-Q-R"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-I-G-T-G-I-D-I-V-E-L-E-R-I-Q-S-M-V-E-K-H-P-R-F-V-K-K-I-L-T-E-N-E-Q-E-V-F-A-R-L-S-R-R-R-R-L-E-Y-I-A-G-R-F-A-A-K-E-A-F-V-K-A-V-G-T-G-I-S-A-E-Y-G-W-H-D-L-E-V-L-S-D-E-R-G-K-P-V-L-S-V-N-L-D-A-T-I-H-V-S-I-S-H-S-Q-S-Y-A-I-A-Q-V-I-L-E-R-L-S-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-E-K-V-I-K-Q-I-V-T-I-N-L-E-A-G-K-A-N-P-A-K-V-G-K-D-L-A-P-T-G-I-N-L-L-G-F-C-N-Q-Y-N-E-M-T-K-L-Q-L-G-L-V-V-P-A-K-I-T-I-Y-E-D-R-S-F-N-V-K-L-K-T-P-P-A-A-F-L-L-K-K-Y-A-G-V-E-K-G-A-A-Q-P-G-K-E-V-V-G-S-I-T-T-Q-Q-L-R-T-I-A-E-I-K-L-P-D-L-N-T-T-S-I-D-R-A-M-K-I-I-A-G-T-A-R-N-M-G-I-N-I-E-D-D"} +{"text": "### FUNCTION Possible metal-dependent hydrolase ### SEQUENCE -M-D-N-R-Y-P-I-G-Q-F-N-C-P-S-E-V-Q-E-K-D-I-Q-M-W-I-K-E-I-T-T-L-P-S-R-L-H-A-L-T-V-S-L-D-E-L-E-L-T-K-T-Y-R-E-N-S-W-N-V-R-Q-L-I-H-H-I-S-D-S-H-L-N-G-Y-M-R-M-K-L-A-L-T-E-D-N-P-V-V-K-T-Y-E-E-S-E-W-A-K-L-I-D-Y-E-L-P-I-R-V-S-L-Q-L-L-E-S-L-H-E-R-W-T-Y-L-L-K-N-L-T-A-T-Q-L-Q-R-T-Y-Q-Y-P-D-G-S-I-M-R-I-E-Q-S-I-A-L-Y-A-W-H-G-N-H-H-L-A-H-I-Q-Q-A-L-I-R-T-K"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-Y-V-H-S-V-I-G-N-I-E-A-K-T-P-T-K-T-I-E-W-I-E-L-D-W-D-E-L-N-K-R-I-L-R-K-T-T-D-H-G-R-E-V-A-I-V-M-E-E-Q-G-L-T-F-G-D-I-L-Y-E-G-E-D-V-A-I-A-V-R-T-K-L-E-P-A-F-V-I-R-P-K-T-M-K-E-M-G-K-T-A-F-E-L-G-N-R-H-T-P-C-L-V-E-N-D-E-I-Y-V-R-Y-D-S-T-L-A-A-L-F-N-E-I-G-V-N-Y-E-Q-T-E-K-R-F-K-Q-P-F-K-Y-K-G-H-H-H-H-H-D"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-Y-M-A-K-P-N-E-V-E-R-K-W-Y-V-V-D-A-E-G-Q-T-L-G-R-L-A-S-E-V-A-S-I-L-R-G-K-H-K-P-T-Y-T-P-H-V-D-T-G-D-H-V-I-I-I-N-A-E-K-I-H-L-T-G-N-K-L-Q-D-K-I-Y-Y-R-H-S-G-H-P-G-G-L-K-E-T-R-A-A-D-M-R-A-N-K-P-E-K-M-L-E-L-A-I-K-G-M-L-P-K-N-T-L-G-R-K-Q-G-M-K-L-H-V-Y-A-G-S-E-H-K-H-Q-A-Q-K-P-E-V-Y-E-L-R-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-K-D-Q-I-I-E-A-I-K-E-M-T-V-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-V-A-G-G-A-A-A-E-G-G-A-A-E-K-T-E-F-D-V-V-L-E-S-A-G-G-S-K-I-N-V-I-K-V-V-R-E-I-T-G-L-G-L-K-E-A-K-A-L-V-D-G-A-P-A-P-I-K-E-G-V-A-K-E-E-A-E-E-M-K-A-K-L-E-E-A-G-A-S-V-E-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-V-L-E-Q-K-K-Q-I-V-T-E-I-A-T-K-L-K-E-S-Q-S-T-V-V-V-D-Y-R-G-L-N-V-A-E-V-T-E-L-R-K-Q-L-R-E-A-G-C-E-F-K-V-Y-K-N-T-M-T-R-R-A-A-E-V-A-E-L-T-E-L-N-D-V-L-V-G-P-T-A-I-A-F-H-N-E-D-A-I-A-P-A-K-I-I-N-S-F-A-K-E-H-E-A-L-E-I-K-A-G-V-I-E-G-N-V-A-S-V-E-E-V-K-A-L-A-E-L-P-S-R-E-G-L-L-S-M-L-L-S-V-L-Q-A-P-V-R-N-F-A-L-A-T-K-A-V-A-D-Q-K-E-E-Q-G-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-I-K-M-V-K-L-Q-I-P-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-A-G-V-N-I-M-G-F-C-K-E-F-N-A-R-T-S-D-Q-A-G-L-I-I-P-V-E-I-T-V-F-E-D-R-S-F-T-F-V-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-I-E-S-G-S-G-E-P-N-R-N-K-V-A-T-V-K-R-D-K-V-R-E-I-A-E-T-K-M-P-D-L-N-A-A-D-V-E-A-A-M-R-M-V-E-G-T-A-R-S-M-G-I-V-I-E-D"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-E-K-N-W-Y-V-V-H-T-Y-S-G-Y-E-N-K-V-K-T-N-L-E-K-R-V-E-S-M-D-M-T-D-K-I-F-R-V-M-V-P-V-E-E-E-T-E-V-K-N-G-K-S-K-Q-V-S-R-K-V-F-P-G-Y-V-L-V-E-M-V-M-T-D-D-S-W-Y-V-V-R-N-T-P-G-V-T-G-F-V-G-S-A-G-A-G-S-K-P-T-P-L-L-P-E-E-V-D-A-I-L-R-Q-M-G-M-Q-E-E-R-Q-V-E-I-D-F-Q-L-K-E-S-V-K-V-K-E-G-P-F-A-N-F-I-G-T-I-E-E-I-Q-L-D-K-R-K-L-K-V-H-V-N-M-F-G-R-E-T-P-V-E-L-E-F-T-Q-I-E-K-I"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-A-G-G-V-K-G-I-G-K-F-F-G-D-V-V-A-E-M-K-R-V-S-W-P-T-R-K-E-L-T-R-Y-T-L-V-V-L-G-T-V-A-F-I-T-V-F-F-A-V-V-D-Y-G-I-S-A-L-V-R-G-L-I-E"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-V-G-L-G-N-P-G-A-K-Y-D-G-T-R-H-N-V-G-F-D-V-V-D-A-V-A-R-R-L-N-I-E-I-K-Q-S-K-A-N-G-L-Y-G-E-G-R-I-D-G-E-K-I-F-L-L-K-P-Q-T-F-M-N-R-S-G-E-S-V-R-P-F-L-E-Y-Y-N-M-E-V-E-D-L-L-V-I-Y-D-D-L-D-L-P-V-G-K-I-R-L-R-Q-K-G-S-A-G-G-H-N-G-M-K-S-L-I-A-H-L-G-T-S-D-F-K-R-I-R-V-G-V-D-R-P-A-P-G-E-T-V-V-Q-H-V-L-G-R-Y-R-P-E-E-K-D-A-I-S-E-A-I-D-L-S-A-E-A-A-E-A-F-T-K-K-P-F-L-E-V-M-N-T-F-N"} +{"text": "### FUNCTION Essential for sporulation Interferes with or is a negative regulator of the pathway leading to asymmetric septation ### SEQUENCE -M-Q-V-T-D-V-R-L-R-R-V-N-T-E-G-R-M-K-A-I-A-S-I-T-I-D-H-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-S-S-Q-T-R-E-K-I-Q-T-A-V-L-A-E-Y-E-R-A-G-E-L-D-Q-V-T-Y-E-E-A-G-A-S"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Q-Y-P-E-P-I-A-K-L-I-E-G-F-M-R-L-P-G-I-G-P-K-T-A-S-R-L-A-F-F-V-L-E-M-K-E-D-D-V-L-D-F-A-K-A-L-V-N-V-K-R-K-L-T-Y-C-S-V-C-H-N-I-T-D-T-D-P-C-R-I-C-E-D-S-K-R-D-E-S-V-I-C-V-V-Q-D-A-K-D-V-I-A-M-E-K-M-K-E-Y-H-G-K-Y-H-V-L-H-G-A-I-S-P-M-D-G-I-G-P-E-D-I-K-I-P-E-L-I-K-R-L-Q-D-D-T-I-Q-E-V-I-V-A-T-N-P-T-I-E-G-E-A-T-A-M-Y-I-S-R-L-V-K-P-T-G-I-K-V-T-R-I-A-H-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-M-E-G-R-R-E-L"} +{"text": "### FUNCTION Inhibitor of the alkaline protease ### SEQUENCE -M-P-S-S-V-Q-A-T-A-G-L-L-A-T-L-M-M-F-C-G-E-V-A-M-A-R-S-L-L-L-A-E-P-S-Q-L-A-G-Q-W-Q-A-V-L-S-S-P-Q-D-N-A-Q-T-Q-A-M-Q-D-K-P-S-N-S-C-L-V-E-L-K-V-D-Q-T-L-G-G-Q-T-D-C-L-G-Q-W-L-G-D-E-P-V-R-W-F-T-E-P-D-G-L-S-L-I-G-K-Q-D-S-R-T-H-L-G-L-R-Q-G-D-H-Y-Q-M-T-L-K-S-G-L-I-L-R-L-E-R-N-K-S-Q-S-A-H"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-S-E-L-I-D-A-I-A-A-S-A-D-L-P-K-A-A-A-G-R-A-L-D-A-V-I-E-S-V-T-G-A-L-K-A-G-D-S-V-V-L-V-G-F-G-T-F-S-V-T-D-R-P-A-R-I-G-R-N-P-Q-T-G-K-T-L-E-I-A-A-A-K-K-P-G-F-K-A-G-K-A-L-K-E-A-V-N"} +{"text": "### FUNCTION Participates in the reduction of hydrogensulfite from hydrogen ### SEQUENCE -M-K-R-S-L-G-A-K-P-L-L-F-P-T-P-V-L-V-V-G-T-Y-D-D-Q-G-R-P-N-A-M-T-A-A-W-G-G-I-C-C-S-K-P-P-C-V-T-V-S-L-R-K-A-T-Y-T-Y-A-S-L-M-A-R-K-A-Y-T-L-H-V-T-D-E-P-H-L-T-A-S-D-F-L-G-M-A-S-G-R-D-G-D-K-L-G-T-L-G-L-T-T-V-R-S-E-L-V-D-A-P-I-I-Q-E-Y-P-L-V-L-E-C-K-I-V-H-V-H-D-L-G-L-H-T-M-F-V-G-E-V-Q-D-I-K-A-D-A-R-V-L-D-E-K-G-H-L-L-L-D-A-L-K-P-L-G-F-M-P-E-V-R-T-Y-H-G-M-G-P-A-L-G-R-A-F-D-A-G-K-L-H-M-P-K-K-A-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-Q-P-I-G-D-R-V-I-V-K-V-K-D-E-E-E-E-K-V-G-G-I-V-L-A-S-N-A-K-E-K-P-Q-M-G-E-I-I-A-V-G-N-G-K-R-N-A-N-G-D-L-I-P-M-S-V-A-K-G-E-T-V-F-F-D-K-Y-S-G-T-N-L-K-Y-E-G-E-K-Y-L-V-L-R-E-S-D-L-L-A-V-V-K"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-K-T-L-K-N-F-N-E-L-V-D-A-E-D-F-L-N-F-F-E-I-P-F-D-Q-T-T-V-N-V-N-R-L-H-I-L-K-V-F-S-S-A-I-A-E-V-D-E-N-T-K-L-T-E-T-E-K-I-T-A-Y-K-A-G-L-E-S-A-Y-K-T-F-L-T-S-N-A-Q-E-Q-K-V-F-P-V-F-Q-K-E-H-K-D-V-V-K-L-T-E-I-S-A-E"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-E-K-R-E-F-N-I-I-A-E-T-G-I-H-A-R-P-A-T-L-L-V-Q-A-A-S-K-F-N-S-D-I-N-L-E-Y-K-G-K-S-V-N-L-K-S-I-M-G-V-M-S-L-G-V-G-Q-G-A-D-V-T-I-S-A-E-G-A-D-E-A-D-A-I-A-A-I-T-D-T-M-K-K-E-G-L-A-E"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-D-T-I-V-D-F-K-A-L-P-Y-R-K-C-V-G-I-L-V-F-N-Y-E-G-K-V-W-V-G-R-R-L-M-T-V-S-H-A-N-V-D-M-S-K-L-W-Q-L-P-Q-G-G-I-N-Q-G-E-K-P-I-D-A-A-R-R-E-L-Y-E-E-T-G-I-Q-S-V-K-L-I-K-E-A-Q-D-W-F-E-Y-D-F-P-Q-E-L-M-G-H-V-L-N-N-K-Y-R-G-Q-T-Q-K-W-F-S-F-Q-F-T-G-E-I-S-E-I-T-I-N-P-P-P-D-G-N-K-A-E-F-D-Q-W-K-W-V-D-L-E-E-L-P-S-I-V-V-S-F-K-K-H-V-Y-T-Q-V-V-K-E-F-R-N-S-F-K-Y-L"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-K-P-F-G-D-R-V-V-I-K-K-V-E-A-E-E-K-T-A-S-G-I-V-L-P-G-A-A-K-E-Q-P-Q-I-A-E-V-V-E-V-G-P-G-G-I-V-E-G-K-E-I-K-M-E-L-T-V-G-D-K-V-I-F-Q-K-Y-S-G-T-E-V-K-I-E-G-Q-E-Y-T-I-L-R-Q-S-D-V-L-A-V-I-E"} +{"text": "### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate with acetyl coenzyme A ### SEQUENCE -M-I-Y-P-Q-I-M-H-K-P-A-L-P-W-V-F-R-R-P-T-Q-E-D-G-L-S-I-H-E-L-I-A-Q-C-A-P-L-D-Q-N-S-A-Y-C-N-F-L-Q-S-S-H-F-Q-T-T-C-L-M-A-E-Q-Q-E-L-L-V-G-F-V-S-A-Y-R-K-P-E-Q-Q-N-E-L-F-I-W-Q-V-A-V-H-P-S-A-R-G-K-G-L-A-Y-Q-M-L-K-H-L-L-A-R-E-D-L-A-D-I-T-V-L-E-T-T-I-T-R-S-N-Q-A-S-W-R-L-F-Q-K-L-D-R-E-Q-G-E-Q-G-S-V-S-T-F-L-D-E-T-C-H-F-E-G-E-H-D-T-E-Y-L-Y-R-I-P-L-Q-S-S-N"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-R-T-L-E-E-C-R-Q-S-E-R-R-V-V-A-E-N-W-E-S-V-R-M-L-L-K-D-D-H-M-G-F-S-F-H-I-T-T-I-Y-A-N-T-Q-T-H-I-H-Y-R-N-H-L-E-S-V-Y-C-M-S-G-E-G-E-I-E-V-V-G-G-K-T-Y-P-I-Q-P-G-T-L-Y-I-L-D-Q-H-D-E-H-Y-L-R-A-F-S-S-E-M-V-M-A-C-V-F-N-P-P-L-T-G-H-E-I-H-D-A-E-G-V-Y-P-L-D-K-S-E-L-I-S-Q-C-H-K-E-K"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-K-K-T-T-R-T-M-A-A-H-K-H-V-A-L-V-A-H-D-N-C-K-G-E-L-L-R-W-V-T-E-N-K-E-K-L-Q-R-H-F-L-Y-A-T-G-T-T-G-H-M-L-S-K-E-T-G-L-A-I-K-S-M-I-S-G-P-M-G-G-D-Q-Q-L-G-A-L-I-S-E-G-K-I-D-V-L-I-F-F-W-D-P-L-N-A-V-P-H-D-P-D-V-K-A-L-L-R-I-A-S-V-W-N-I-P-V-A-T-N-R-A-S-A-K-F-L-F-S-S-S-L-M-E-Q-E-V-Q-I-E-I-P-D-Y-Q-A-Y-L-A-E-R-T"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-L-L-K-E-F-K-A-F-A-S-R-G-N-V-I-D-M-A-V-G-I-I-I-G-A-A-F-G-K-I-V-S-S-F-V-A-D-I-I-M-P-P-I-G-I-I-L-G-G-V-N-F-S-D-L-S-F-V-L-L-A-A-Q-G-D-A-P-A-V-V-I-A-Y-G-K-F-I-Q-T-V-V-D-F-T-I-I-A-F-A-I-F-M-G-L-K-A-I-N-S-L-K-R-K-E-E-E-A-P-K-A-P-P-A-P-T-K-D-Q-E-L-L-S-E-I-R-D-L-L-K-A-Q-Q-D-K"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system that counteracts the effect of the HigB-2 toxin Binds to its own promoter and regulates transcription of the higB-2/higA-2 operon ### SEQUENCE -M-S-N-R-D-L-F-A-E-L-S-S-A-L-V-E-A-K-Q-H-S-E-G-K-L-T-L-K-T-H-H-V-N-D-V-G-E-L-N-I-S-P-D-E-I-V-S-I-R-E-Q-F-N-M-S-R-G-V-F-A-R-L-L-H-T-S-S-R-T-L-E-N-W-E-Q-G-R-S-V-P-N-G-Q-A-V-T-L-L-K-L-V-Q-R-H-P-E-T-L-S-H-I-A-E-L"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Inhibits translation by cleavage of mRNA ### SEQUENCE -M-K-S-V-F-V-E-S-T-I-F-E-K-Y-R-D-E-Y-L-S-D-E-E-Y-R-L-F-Q-A-E-L-M-L-N-P-K-L-G-D-V-I-Q-G-T-G-G-L-R-K-I-R-V-A-S-K-G-K-G-K-R-G-G-S-R-I-I-Y-Y-F-L-D-E-K-R-R-F-Y-L-L-T-I-Y-G-K-N-E-M-S-D-L-N-A-N-Q-R-K-Q-L-M-A-F-M-E-A-W-R-N-E-Q-S"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system that counteracts the effect of the HigB-1 toxin Binds to its own promoter and regulates transcription of the higB-1/higA-1 operon ### SEQUENCE -M-R-K-T-K-R-R-P-V-S-V-G-E-M-L-K-V-E-F-L-E-P-M-G-I-T-S-K-A-L-A-E-A-M-G-V-H-R-N-T-V-S-N-L-I-N-G-G-V-L-T-A-P-V-A-I-K-L-A-A-A-L-G-N-T-P-E-F-W-L-N-I-Q-H-A-V-D-L-W-D-T-R-N-R-Y-Q-E-E-A-K-F-V-K-P-L-F-V-S-L-E-Q-S-A-R-T"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system Inhibits translation by cleavage of mRNA ### SEQUENCE -M-A-L-E-F-K-D-K-W-L-E-Q-F-Y-E-D-D-K-R-H-R-L-I-P-S-S-I-E-N-A-L-F-R-K-L-E-I-L-D-A-A-Q-A-E-S-D-L-R-I-P-P-G-N-R-F-E-H-L-E-G-N-L-K-G-W-C-S-I-R-V-N-K-Q-Y-R-L-I-F-Q-W-V-D-G-V-A-L-N-T-Y-L-D-P-H-K-Y"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-D-K-T-L-K-F-T-E-S-H-E-W-V-R-D-N-G-D-G-T-V-T-I-G-I-S-E-H-A-Q-E-M-L-G-D-V-V-F-V-E-L-P-E-I-D-A-E-I-D-A-G-D-S-F-S-L-V-E-S-V-K-A-A-S-D-I-Y-A-P-V-T-G-V-V-I-E-V-N-E-D-L-Q-N-S-P-E-L-I-N-E-E-P-Y-D-G-G-W-I-V-K-V-K-M-S-D-P-D-E-L-K-D-L-K-D-A-E-E-Y-L-A-S-I-E-E-D"} +{"text": "### FUNCTION A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex ### SEQUENCE -M-V-A-V-L-A-R-Q-G-R-E-L-A-K-R-L-L-L-I-Q-F-S-A-V-M-V-A-A-A-V-F-A-V-A-V-N-G-D-W-G-L-S-A-L-V-G-G-G-I-F-V-I-A-N-A-V-F-A-G-C-A-F-L-F-A-G-A-R-A-L-K-M-V-A-I-S-F-Y-T-G-E-A-L-K-I-L-I-T-I-V-L-F-S-V-A-Y-M-Y-M-Q-L-E-L-V-P-L-K-L-T-Y-L-L-A-L-G-I-N-I-C-A-P-V-L-F-I-N-N-K-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-M-N-A-T-L-L-G-Q-A-I-S-F-G-M-F-V-W-F-C-M-K-Y-V-W-P-P-I-I-K-A-I-E-D-R-Q-K-K-I-A-D-G-L-Q-A-A-E-R-A-K-K-D-L-D-L-A-Q-A-N-A-S-D-Q-L-K-E-A-K-R-T-A-T-E-L-I-E-Q-A-N-K-R-K-A-Q-I-I-D-E-A-R-E-E-A-Q-A-E-R-Q-K-I-L-T-Q-A-E-A-E-I-E-A-E-R-N-R-A-R-D-E-L-R-K-Q-V-A-T-L-A-I-A-G-A-E-K-I-L-E-R-S-I-D-K-D-T-H-K-D-I-L-D-N-I-T-A-K-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-D-L-T-T-I-A-R-P-Y-A-K-A-A-F-D-F-A-V-E-K-Q-Q-L-G-H-W-S-Q-M-L-A-F-T-A-E-V-A-K-N-E-Q-M-H-E-L-L-T-S-S-G-S-A-N-K-L-A-E-I-F-I-A-V-C-G-E-Q-L-D-G-H-G-Q-N-L-I-K-V-M-A-E-N-G-R-L-L-A-I-P-A-L-Y-E-H-F-A-V-L-K-Q-E-H-E-K-K-V-D-V-E-V-I-S-A-T-E-L-S-E-Q-Q-R-S-E-I-G-S-K-L-E-Q-R-L-E-R-K-V-Q-L-N-C-S-V-D-E-T-L-L-G-G-V-I-I-R-A-G-D-L-V-I-D-N-S-A-R-G-R-L-K-R-L-S-D-A-L-Q-S"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-S-N-P-I-T-I-T-E-S-A-Q-S-H-F-A-K-L-L-A-Q-Q-P-E-G-T-N-I-R-V-F-V-V-N-P-G-T-Q-N-A-E-C-G-V-S-Y-C-P-P-E-A-V-E-A-T-D-T-E-Y-P-F-S-G-F-S-A-Y-V-D-E-L-S-L-P-F-L-E-E-A-V-I-D-F-V-T-D-K-M-G-S-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-S-D-D-A-S-L-M-E-R-V-E-Y-A-L-Q-T-Q-V-N-P-Q-L-A-G-H-G-G-H-V-R-L-I-S-I-S-D-D-G-V-A-L-V-Q-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-E-G-I-E-K-E-L-L-A-Q-F-A-G-E-L-T-A-V-R-D-S-T-E-H-D-R-G-E-H-S-Y-Y"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-K-T-K-L-I-T-R-A-G-Y-N-K-L-K-Q-E-L-D-Y-L-W-K-E-Q-R-P-E-I-T-Q-K-V-S-W-A-A-S-L-G-D-R-S-E-N-A-D-Y-T-Y-N-K-R-L-L-R-Q-I-D-R-R-V-R-F-L-S-K-L-L-P-E-L-K-I-V-D-Y-S-P-Q-Q-E-G-K-V-F-F-G-A-W-V-E-I-E-N-E-A-G-E-V-K-K-F-R-I-V-G-P-E-E-I-Y-G-D-A-K-D-Y-I-S-I-D-S-P-M-A-R-A-L-L-K-K-Q-V-D-E-E-F-Q-V-H-T-P-T-G-I-K-E-W-F-I-N-S-I-E-Y-E-K-G-E-L"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-D-A-V-E-K-I-G-N-R-F-D-L-V-L-V-A-A-R-R-A-R-Q-M-Q-S-G-G-K-D-A-L-V-P-E-E-N-D-K-P-T-V-I-A-L-R-E-I-E-E-G-L-I-T-K-D-V-L-D-A-R-E-R-Q-E-Q-Q-E-Q-E-A-A-E-L-A-A-V-S-S-I-M-H-N-R"} +{"text": "### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-F-E-V-L-E-K-L-E-A-K-I-Q-T-A-V-D-T-I-A-L-L-Q-M-E-V-E-E-L-K-E-E-K-Q-Q-L-Q-N-E-A-Q-E-L-R-E-A-R-E-A-L-E-Q-R-A-Q-Q-V-Q-Q-E-H-A-A-W-Q-E-R-I-R-S-L-L-G-K-M-E-D-V-E"} +{"text": "### FUNCTION This regulatory protein, when combined with SAM represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-A-D-W-N-G-E-Y-I-S-P-Y-A-E-H-G-K-K-S-E-L-V-K-K-I-T-V-S-I-P-L-K-V-L-K-V-L-T-D-E-R-T-R-R-Q-V-N-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-Y-T-G-Q-P-L-P-T-D-E-D-L-R-K-D-R-P-D-D-I-P-A-E-A-K-R-L-M-T-E-M-G-I-E-F-E-S-Y-D-E"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-G-I-H-P-E-Y-K-A-V-N-A-T-C-S-C-G-N-S-F-V-F-N-S-T-L-G-K-D-T-M-H-L-D-V-C-D-K-C-H-P-F-Y-S-G-K-Q-R-I-V-D-T-G-G-R-V-E-R-F-N-K-R-F-G-A-L-S-A-K-K"} +{"text": "### FUNCTION Globally modulates RNA abundance by binding to RNase E and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome Modulates RNA-binding and helicase activities of the degradosome ### SEQUENCE -M-E-Y-N-T-S-A-L-C-D-I-Y-L-D-Q-V-D-V-V-E-P-M-F-S-N-F-G-G-C-A-S-F-A-G-Q-I-T-T-I-K-C-Y-E-D-N-G-L-I-R-E-T-L-E-Q-D-G-L-G-R-I-L-L-I-D-G-G-G-S-L-R-R-A-L-I-D-A-E-L-A-A-L-A-E-E-N-E-W-E-G-I-V-V-Y-G-S-V-R-E-V-D-E-L-E-E-M-S-I-G-I-Q-A-I-A-S-I-P-V-G-A-T-S-Q-G-I-G-E-V-D-I-P-V-N-F-G-G-V-T-F-L-P-E-D-Y-L-Y-A-D-N-T-G-I-I-I-S-Q-E-P-L-S-A-D-L-G-E-E-E-E-D-E-L-L"} +{"text": "### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-T-V-S-T-N-E-F-K-G-G-L-K-I-M-L-D-N-E-P-C-V-I-L-E-N-E-Y-V-K-P-G-K-G-Q-A-F-N-R-V-R-I-R-K-L-L-T-G-K-V-L-E-K-T-F-K-S-G-D-T-A-E-V-A-D-V-V-D-I-D-L-D-Y-L-Y-N-D-G-E-F-Y-H-F-M-N-N-S-T-F-E-Q-L-A-A-D-A-K-A-V-G-E-N-A-K-W-L-V-E-N-N-T-C-M-L-T-L-W-N-G-N-P-I-A-V-T-P-P-N-F-V-E-L-E-V-T-E-T-D-P-G-V-K-G-D-T-Q-G-T-G-G-K-P-A-T-L-S-T-G-A-V-V-R-V-P-L-F-V-Q-I-G-E-V-I-K-V-D-T-R-S-A-E-Y-V-G-R-V-K"} +{"text": "### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-F-L-L-W-C-K-E-L-I-V-I-N-T-N-P-K-R-S-D-E-P-V-W-W-S-L-F-G-A-G-G-T-W-F-A-M-I-T-P-I-T-V-L-V-L-G-I-L-A-P-L-G-V-I-D-A-E-A-L-S-Y-E-R-V-S-S-F-A-T-S-I-I-G-A-L-F-I-I-G-T-L-A-L-P-M-W-H-A-M-H-R-V-H-H-G-M-H-D-L-K-F-H-T-G-V-A-G-K-I-A-C-Y-G-F-A-T-I-I-S-A-L-A-V-V-F-I-F-M-I"} +{"text": "### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-S-N-R-K-P-Y-V-R-E-M-K-R-T-W-W-K-D-H-P-F-Y-R-F-Y-M-V-R-E-A-T-V-L-P-L-I-L-F-T-L-F-L-T-V-G-L-G-S-L-V-K-G-P-E-A-W-Q-T-W-L-D-F-M-A-N-P-L-V-I-A-I-N-L-V-A-L-A-G-S-L-F-H-A-Q-T-F-F-S-M-M-P-Q-V-V-P-I-R-L-G-G-K-L-V-D-K-K-I-I-V-L-A-Q-W-A-A-V-A-F-I-S-L-I-V-L-I-V-V"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-A-E-A-A-Q-A-P-Q-Q-Q-F-A-I-Q-R-I-Y-L-K-D-V-S-F-E-A-P-S-S-P-V-M-F-Q-K-E-W-N-P-D-V-K-L-D-L-D-T-Q-S-R-E-L-G-Q-G-V-Y-E-V-V-L-R-L-T-V-T-V-K-N-A-E-E-T-A-F-L-C-E-V-Q-Q-A-G-I-F-S-A-E-Q-M-E-A-G-Q-L-A-H-C-L-G-A-F-C-P-N-I-L-F-P-Y-A-R-E-T-I-S-S-L-V-V-K-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-M-N-Y-L-Q-Q-Q-A-Q-E-G-A-T-A-N-A"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-R-I-R-I-R-L-K-A-F-D-Y-K-L-I-D-A-S-T-A-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-R-F-T-V-L-I-S-P-H-V-N-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-L-I-D-I-V-E-P-T-D-K-T-V-D-A-L-M-R-L-D-L-A-A-G-V-D-V-Q-I-S-L-G"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-R-E-E-R-L-L-K-V-L-R-A-P-H-I-S-E-K-A-T-M-S-A-E-K-S-N-T-I-V-F-K-V-A-K-D-A-T-K-K-E-I-K-A-A-V-E-K-L-F-E-V-E-V-K-S-V-N-T-L-I-I-K-G-K-T-K-R-Q-G-L-R-Q-G-R-R-S-D-V-K-K-A-Y-V-T-L-N-E-G-Q-D-L-D-F-V-G-G-A-E"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-V-E-K-A-V-E-S-G-D-K-K-P-I-K-T-W-S-R-R-S-M-I-I-P-T-M-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-F-V-T-D-E-M-I-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-A-A-D-K-K-A-K-K-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-I-A-K-H-N-F-A-R-I-S-P-Q-K-A-R-L-V-A-D-Q-I-R-G-K-S-V-D-Q-A-L-E-L-L-T-F-S-N-K-K-A-A-E-L-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-E-G-A-D-I-D-D-L-R-V-A-K-I-F-V-D-E-G-P-V-M-K-R-I-M-P-R-A-K-G-R-A-D-R-I-L-K-R-S-S-H-I-T-V-V-V-A-D-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-V-Q-T-G-R-N-R-G-L-A-K-G-T-E-V-S-F-G-T-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-H-I-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-E-V-R-Q-G-K-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-K-V-M-Y-E-V-D-G-V-P-E-E-L-A-R-E-A-F-R-L-A-A-R-K-L-P-F-K-T-T-F-V-T-K-Q-V-M"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-D-K-I-R-T-Q-L-G-R-V-V-S-D-K-M-D-K-S-I-V-V-A-I-E-R-M-V-K-H-P-I-Y-G-K-F-V-K-R-T-T-K-V-H-A-H-D-E-N-N-E-C-G-I-G-D-T-V-E-I-R-E-C-R-P-L-S-K-T-K-S-W-T-L-V-K-I-V-E-K-A-K-M"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-M-L-D-A-A-D-N-S-G-A-R-S-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-H-V-G-D-I-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-D-V-L-K-A-V-V-V-R-T-R-K-G-V-R-R-P-D-G-S-V-I-R-F-D-R-N-A-C-V-L-L-N-N-N-S-E-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-N-A-K-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-Q-N-D-E-V-I-V-L-A-G-K-D-K-G-K-K-G-K-V-T-K-V-L-A-T-G-K-V-I-V-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-M-G-V-Q-G-G-I-V-E-Q-E-A-A-I-D-V-S-N-I-A-I-F-N-A-K-T-G-K-A-D-R-I-G-F-R-F-E-D-G-K-K-V-R-F-F-K-S-N-N-E-I-V-S-N"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-K-S-S-V-V-A-E-L-T-K-Q-F-S-Y-T-S-V-M-Q-V-P-R-I-E-K-I-T-L-N-M-G-V-G-E-A-I-N-D-K-K-L-L-E-N-A-A-S-D-M-A-I-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-V-A-G-F-K-I-R-E-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-D-F-L-E-R-L-I-S-I-A-L-P-R-V-R-D-F-R-G-V-N-G-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-Y-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-T-A-G-T-D-E-E-G-R-A-L-L-A-A-F-N-F-P-F-R-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-E-E-K-R-A-K-L-V-A-Q-F-A-E-K-R-A-T-L-K-A-I-I-S-D-V-N-A-S-E-E-D-R-W-N-A-V-L-K-L-Q-S-L-P-R-D-S-S-R-S-R-Q-R-N-R-C-N-Q-T-G-R-P-H-G-F-L-R-K-F-G-L-S-R-I-K-V-R-E-A-C-M-K-G-E-I-P-G-L-R-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-S-D-M-L-T-R-I-R-N-G-Q-A-A-N-K-V-A-V-K-M-P-S-S-K-L-K-V-A-I-A-A-L-L-K-A-E-G-Y-I-A-D-F-A-V-E-G-E-V-K-A-E-L-E-I-T-L-K-Y-F-Q-A-K-P-V-I-E-Q-I-K-R-V-S-R-P-G-L-R-V-Y-K-K-K-D-E-L-P-S-V-M-G-G-L-G-V-A-V-V-S-T-S-K-G-L-M-S-D-R-A-A-R-K-A-G-L-G-G-E-I-I-C-Y-V-A"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-A-I-P-A-G-V-E-V-K-L-N-G-Q-E-I-T-I-K-G-A-K-G-E-L-T-R-V-F-H-N-G-V-V-I-A-Q-E-D-N-Q-L-T-F-G-P-R-E-G-V-A-N-A-W-A-Q-A-G-T-A-R-A-L-V-K-N-M-V-V-G-V-T-E-G-F-T-K-K-L-V-L-K-G-V-G-Y-R-A-A-M-K-G-N-A-V-G-L-T-L-G-F-S-H-P-V-E-H-E-L-P-A-G-V-K-A-E-C-P-S-Q-T-E-I-V-L-T-G-C-D-K-Q-V-V-G-Q-V-A-A-D-I-R-S-Y-R-A-P-E-P-Y-K-G-K-G-I-R-Y-A-D-E-N-V-R-S-K-E-A-K-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-A-S-R-I-R-R-A-T-R-A-R-R-K-I-A-E-L-G-A-T-R-L-V-V-H-R-T-P-R-H-V-Y-A-Q-V-I-A-A-N-G-S-E-V-I-A-A-A-S-T-V-E-K-A-I-R-E-Q-V-K-Y-T-G-N-I-D-A-A-K-A-V-G-K-A-V-A-E-R-A-L-E-K-G-V-T-V-V-A-F-D-R-S-G-F-Q-Y-H-G-R-V-A-A-L-A-D-S-A-R-E-A-G-L-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-K-E-Q-Q-V-Q-A-N-D-L-Q-E-K-L-I-A-V-N-R-V-S-K-T-V-K-G-G-R-I-M-S-F-T-A-L-T-V-V-G-D-G-N-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-S-M-V-T-I-A-L-N-E-G-T-L-H-H-P-V-K-G-R-H-S-G-S-K-V-Y-M-Q-P-A-A-E-G-T-G-V-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-H-N-V-L-S-K-A-Y-G-S-T-N-P-I-N-I-V-R-A-T-I-D-A-L-V-D-V-K-S-P-E-M-V-A-A-K-R-G-L-T-V-E-A-I-S-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-L-L-N-T-L-S-P-A-A-G-S-K-H-A-P-K-R-L-G-R-G-V-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-K-S-R-S-G-G-K-V-R-P-G-F-E-G-G-Q-M-P-L-K-Q-R-L-P-K-F-G-F-T-S-R-K-S-F-V-S-A-E-V-R-L-S-E-L-A-K-V-T-G-D-V-V-D-L-N-A-L-K-A-A-N-L-V-T-K-N-I-E-F-A-K-I-V-L-S-G-E-I-N-K-A-V-T-V-K-G-L-R-V-T-K-G-A-K-A-A-I-E-A-A-G-G-K-I-E-E"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-H-K-H-A-V-I-A-L-T-A-I-Y-G-I-G-K-T-R-S-K-A-I-L-A-D-L-G-I-A-E-S-V-K-I-S-E-L-T-E-E-Q-I-D-Q-L-R-D-G-V-A-K-Y-T-V-E-G-D-L-R-R-E-V-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-S-L-P-L-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K"} +{"text": "### FUNCTION Putative gamma-glutamylcyclotransferase ### SEQUENCE -M-Q-H-L-V-F-V-Y-G-T-L-R-H-G-E-S-N-H-T-Y-L-Q-H-S-Q-L-L-G-Q-F-E-T-K-P-E-Y-A-L-Y-D-L-G-A-Y-P-G-L-V-E-G-H-Q-S-V-H-G-E-V-Y-L-V-D-E-H-T-L-A-Q-L-D-I-L-E-D-V-P-V-E-Y-R-R-D-T-I-E-T-P-F-G-T-A-W-I-Y-I-Y-Q-E-T-H-R-L-H-S-L-I-D-S-G-D-W-C-Q-R-V"} +{"text": "### FUNCTION Component of the phosphoenolpyruvate-dependent nitrogen-metabolic phosphotransferase system proteins ### SEQUENCE -M-P-Q-L-S-Q-T-V-L-I-Q-N-R-L-G-L-H-A-R-A-A-V-K-L-V-Q-L-A-Q-S-F-D-A-V-L-T-V-Q-S-Q-D-G-R-E-A-T-A-D-S-V-M-G-L-L-M-L-E-S-A-Q-G-Q-N-V-V-I-S-A-E-G-S-Q-A-E-Q-A-L-Q-A-V-C-Q-L-I-E-Q-K-F-D-E-D-E"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-S-K-E-T-K-L-Q-V-E-A-I-K-N-G-T-V-I-D-H-I-P-A-K-V-G-I-K-V-L-K-L-F-D-M-H-N-S-A-Q-R-V-T-I-G-L-N-L-P-S-S-A-L-G-S-K-D-L-L-K-I-E-N-V-F-I-S-E-A-Q-A-N-K-L-A-L-Y-A-P-H-A-T-V-N-Q-I-E-N-Y-E-V-V-K-K-L-A-L-Q-L-P-E-R-I-N-N-V-F-A-C-P-N-S-N-C-I-S-H-N-E-P-V-E-S-S-F-K-L-S-E-K-N-N-D-I-R-L-K-C-K-Y-C-E-K-V-F-A-R-D-V-V-T-E-I-E-A"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-S-G-F-Q-Q-H-T-G-L-V-V-P-L-D-A-A-N-V-D-T-D-A-I-I-P-K-Q-F-L-Q-K-V-N-R-T-G-F-G-K-H-L-F-H-D-W-R-F-L-D-D-A-G-E-K-A-N-P-E-F-V-M-N-Q-P-R-Y-Q-D-A-S-I-L-L-A-R-E-N-F-G-C-G-S-S-R-E-H-A-P-W-A-L-A-D-Y-G-I-R-V-M-I-A-P-S-F-A-D-I-F-Y-G-N-S-I-N-N-Q-M-V-P-V-R-L-T-E-Q-E-V-D-E-L-F-T-Y-V-H-D-T-E-G-A-T-I-T-V-D-L-E-A-L-S-V-T-A-N-G-K-T-Y-H-F-E-I-D-D-F-R-R-H-C-L-L-N-G-L-D-N-I-G-L-T-L-Q-H-E-A-K-I-A-E-Y-E-A-K-I-P-S-F-L-K"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-Y-T-A-E-Q-K-A-R-I-K-W-A-C-R-R-G-M-L-E-L-D-V-V-I-M-P-F-F-E-E-C-F-D-S-L-T-E-S-E-Q-D-D-F-V-A-L-L-E-S-D-D-P-D-L-F-A-W-V-M-G-H-G-R-C-E-N-L-G-L-A-A-M-V-D-K-I-V-A-H-N-L-S-K-V-R"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-V-G-L-G-T-D-I-A-E-I-E-R-V-E-K-A-L-A-R-S-G-E-N-F-A-R-R-I-L-T-D-S-E-L-E-Q-F-H-A-S-K-Q-Q-G-R-F-L-A-K-R-F-A-A-K-E-A-A-S-K-A-L-G-T-G-I-A-Q-G-V-T-F-H-D-F-T-I-S-H-D-K-L-G-K-P-L-L-I-L-S-G-Q-A-A-E-L-A-S-Q-L-Q-V-E-N-I-H-L-S-I-S-D-E-R-H-Y-A-M-A-T-V-I-L-E-R-R"} +{"text": "### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-T-K-K-L-T-I-V-K-C-P-R-C-G-T-D-V-E-W-G-E-Q-S-P-H-R-P-F-C-S-K-Q-C-Q-M-I-D-F-G-E-W-A-D-E-E-K-A-I-P-G-A-P-D-M-S-D-S-D-G-W-S-E-D-Q-Y"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-P-R-Q-S-P-P-N-L-A-K-L-I-A-L-D-L-L-T-V-G-R-V-P-L-L-L-L-V-L-I-F-S-C-A-M-G-V-V-F-M-T-H-H-T-R-Q-A-I-S-A-K-D-Q-A-F-M-E-R-E-R-L-D-N-E-W-R-N-L-I-L-E-E-T-A-L-A-E-H-S-R-V-Q-Q-L-A-R-K-D-L-E-M-K-R-P-D-S-D-K-E-V-V-I-N-L-K"} +{"text": "### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-Q-G-I-Q-I-T-K-A-A-N-D-D-L-L-N-S-I-W-L-L-D-S-E-K-N-E-A-R-C-V-A-A-L-K-G-F-E-A-D-Q-V-V-S-I-N-D-L-G-Q-F-E-S-R-E-V-A-I-E-A-A-P-R-I-E-G-G-Q-H-L-N-V-N-V-L-K-R-E-T-L-E-D-A-V-A-H-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-A-E-Q-Q-R-D-V-I-A-R-T-F-T-E-S-L"} +{"text": "### FUNCTION Transcriptional regulator that plays an important role in general stress response ### SEQUENCE -M-I-Q-D-V-I-E-K-K-L-S-D-E-F-Q-P-E-F-L-K-V-I-N-E-S-D-M-H-N-V-P-R-G-S-E-S-H-F-K-V-T-V-V-S-E-R-F-A-G-L-R-P-V-A-R-H-R-L-V-N-Q-T-L-A-D-E-L-A-N-H-I-H-A-L-A-I-H-T-Y-T-T-Q-E-W-Q-Q-M-N-Q-E-S-P-E-S-P-M-C-L-G-G-S-R-K-S-A-Q"} +{"text": "### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-S-E-M-T-K-T-P-T-H-Y-R-L-L-S-T-L-K-A-M-G-P-Y-L-R-E-G-Q-C-S-E-R-F-Y-L-F-D-C-L-A-S-C-V-N-D-K-K-S-P-E-K-R-E-F-W-G-W-W-M-E-L-T-Q-N-E-Q-E-M-S-A-C-Y-H-I-G-R-Y-T-L-A-G-D-W-V-A-E-A-I-P-E-S-A-Q-A-E-V-N-H-T-Q-A-E-F-H-K-K-L-V-K-T-L-R-E-R-F-E-I-S-V-T-V-S-T-E-S-A-P-F-A"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-S-E-N-D-T-K-V-I-D-S-R-L-V-A-D-G-H-Q-V-R-R-R-R-Q-C-L-A-C-N-E-R-F-T-T-F-E-T-A-E-L-V-M-P-R-V-I-K-S-N-G-N-R-E-P-F-D-E-E-K-M-I-G-G-L-Q-R-A-L-E-K-R-P-V-S-A-D-A-I-E-L-A-I-S-T-I-K-S-K-L-R-A-T-G-E-R-E-V-P-S-K-L-I-G-N-L-V-M-E-Q-L-K-V-L-D-K-V-A-Y-I-R-F-A-S-V-Y-R-S-F-E-D-V-R-E-F-G-E-E-I-A-K-L-Q-D"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-G-A-S-V-K-P-A-A-R-R-N-A-R-Q-F-A-L-Q-A-I-Y-S-W-Q-I-T-K-E-N-V-A-T-I-E-E-Q-F-L-T-S-G-K-Y-D-E-E-E-H-R-A-A-E-P-A-L-A-A-P-E-T-D-V-S-Y-F-R-D-L-L-A-G-V-V-L-N-H-N-E-L-D-S-K-L-R-P-F-V-S-R-P-M-Q-D-L-D-M-M-E-L-A-L-L-R-L-A-M-Y-E-M-T-R-R-E-D-V-P-Y-K-V-V-I-N-E-A-I-E-L-A-K-V-F-A-A-E-D-S-H-K-F-V-N-G-V-L-D-K-A-A-P-H-V-R-K-K-A"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-E-I-K-K-D-A-Q-E-R-M-E-K-S-V-E-A-L-K-N-G-L-S-K-I-R-T-G-R-A-H-P-S-L-L-T-G-I-S-V-D-Y-Y-G-A-P-T-P-L-N-Q-V-A-N-V-I-A-E-D-A-R-T-L-A-I-T-V-F-D-R-E-L-T-Q-K-V-E-K-A-I-L-M-S-D-L-G-L-N-P-M-S-A-G-T-I-I-R-V-P-L-P-P-L-T-E-E-R-R-R-D-L-V-K-I-V-R-G-E-A-E-G-G-R-V-A-V-R-N-I-R-R-D-A-N-N-D-L-K-A-L-L-K-D-K-E-I-S-E-D-D-E-R-R-A-Q-E-E-I-Q-K-L-T-D-A-A-V-K-K-I-D-D-V-L-A-A-K-E-K-E-L-M-E-V"} +{"text": "### FUNCTION Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm ### SEQUENCE -M-K-N-M-I-K-A-A-S-L-G-L-I-I-L-S-S-S-M-M-A-N-A-A-E-A-A-Q-K-I-G-Y-I-N-T-A-Q-V-F-Q-A-L-P-Q-R-E-V-V-L-Q-K-M-Q-E-E-F-K-D-K-A-A-E-L-Q-A-I-Q-A-D-A-K-T-K-I-E-K-L-K-R-D-G-Q-L-M-G-Q-D-E-V-E-K-L-R-I-E-I-G-Q-L-D-S-K-Y-K-I-K-A-Q-A-L-E-Q-A-S-A-R-R-E-A-E-E-K-Q-K-L-F-K-V-I-Q-D-A-V-K-K-V-A-E-K-E-G-Y-D-I-V-L-D-T-S-S-M-Q-Y-G-K-P-E-H-N-L-S-E-K-V-I-K-A-I-K"} +{"text": "### FUNCTION Catalyzes the decarboxylation of phenolic acids ### SEQUENCE -M-R-F-E-R-N-D-L-S-G-F-L-G-K-S-F-I-Y-N-Y-D-Q-G-W-R-Y-E-L-Y-V-K-N-A-T-T-I-D-Y-R-V-H-S-G-I-V-G-G-R-W-V-K-D-Q-T-V-H-I-S-R-V-G-A-A-I-Y-R-V-S-W-A-E-P-T-G-T-S-V-A-L-T-L-N-L-E-D-Y-V-V-H-G-A-I-Y-F-P-R-W-I-V-D-E-P-E-K-I-A-C-Y-Q-N-D-H-L-P-L-M-E-A-Y-R-D-A-G-P-I-Y-P-T-H-V-I-D-S-F-A-T-L-I-Y-M-R-D-C-G-L-N-N-E-Q-V-I-N-C-P-P-S-E-L-A-E-D-Y-P-F-C-L-A-D-K-N-L-L-P-A"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-Q-P-I-K-L-L-V-G-L-A-N-P-G-P-E-Y-A-K-T-R-H-N-A-G-A-W-V-V-E-E-L-A-R-I-H-N-V-T-L-K-N-E-P-K-F-F-G-L-T-G-R-L-L-I-N-S-Q-E-L-R-V-L-I-P-T-T-F-M-N-L-S-G-K-A-I-A-A-L-A-N-F-Y-Q-I-K-P-E-E-I-M-V-A-H-D-E-L-D-L-P-P-G-V-A-K-F-K-Q-G-G-G-H-G-G-H-N-G-L-K-D-T-I-S-K-L-G-N-N-K-E-F-Y-R-L-R-L-G-I-G-H-P-G-H-K-D-K-V-A-G-Y-V-L-G-K-A-P-A-K-E-Q-E-C-L-D-A-A-V-D-E-S-V-R-C-L-E-I-L-M-K-D-G-L-T-K-A-Q-N-R-L-H-T-F-K-A-E"} +{"text": "### FUNCTION Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins Repression is relieved when the region becomes fully methylated ### SEQUENCE -M-K-T-I-E-V-D-E-D-L-Y-R-Y-I-A-S-Q-T-L-H-I-G-E-S-A-S-D-I-L-R-R-L-L-N-V-D-G-E-L-A-T-A-A-P-A-A-E-P-K-G-I-V-V-S-K-D-A-A-F-D-T-K-I-D-G-V-K-A-M-R-S-L-L-I-S-D-E-F-A-G-L-K-N-A-I-D-R-F-M-L-I-L-S-T-L-H-R-I-D-S-A-S-F-S-E-A-T-M-F-K-G-R-K-R-V-Y-F-A-D-N-E-Q-T-L-L-A-S-G-Q-T-T-K-P-K-A-I-P-N-T-P-F-W-V-I-T-N-N-N-T-S-R-K-Q-Q-M-V-E-Q-V-M-V-R-M-G-F-P-S-D-I-I-E-K-V-T-H-S-I"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-Q-N-Y-Q-L-V-L-A-S-T-S-P-F-R-Q-Q-I-L-A-K-L-K-L-P-F-V-T-A-K-P-D-C-D-E-T-P-L-I-G-E-T-P-E-H-L-L-M-R-L-A-E-N-K-A-R-S-C-F-L-A-D-P-S-L-V-I-G-S-D-Q-V-C-V-I-D-D-Q-I-I-G-K-P-L-T-T-E-K-A-V-E-Q-L-L-R-Q-S-G-Q-A-I-T-F-Y-T-G-L-A-L-F-N-N-Q-T-Q-Q-T-Q-V-L-C-D-T-F-T-V-H-F-R-T-L-S-E-S-M-A-R-R-Y-V-E-A-E-Q-P-L-H-C-A-G-S-F-K-S-E-G-L-G-I-A-L-F-E-R-L-E-G-D-D-P-N-S-L-I-G-L-P-L-I-K-L-I-Q-L-L-E-N-E-G-L-N-V-I"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-L-E-F-F-R-P-Q-K-K-T-S-A-S-V-A-K-E-R-L-Q-I-I-V-A-E-R-R-S-Q-N-D-P-A-P-S-Y-L-P-Q-L-K-E-D-I-L-K-V-I-A-K-Y-V-A-I-D-P-S-M-V-E-L-S-F-E-H-K-G-D-D-I-S-V-L-E-L-N-V-K-L-P-D-D-E-K"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-Q-L-V-E-Q-I-A-A-N-A-D-I-S-K-A-S-A-G-R-A-L-D-A-F-I-E-A-V-S-G-T-L-Q-S-G-D-Q-V-A-L-V-G-F-G-T-F-S-V-R-T-R-A-A-R-T-G-R-N-P-K-T-G-E-E-I-K-I-A-E-A-K-V-P-S-F-K-A-G-K-A-L-K-D-A-C-N"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-R-L-C-A-E-Q-T-H-L-S-A-K-E-I-E-D-A-V-K-N-I-L-E-H-M-A-S-T-L-E-A-G-E-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-E-P-R-V-G-R-N-P-K-T-G-D-K-V-E-L-E-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-E-R-V-N-L"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-R-I-L-S-S-L-K-T-F-S-Q-S-R-L-S-W-L-L-L-L-A-F-V-V-F-F-T-L-C-A-M-Y-F-Q-H-V-M-L-L-A-P-C-V-M-C-I-Y-E-R-I-A-M-L-G-I-G-V-A-A-L-I-G-A-I-A-P-Q-N-P-V-V-R-W-L-G-F-A-A-W-G-A-S-S-Y-K-G-L-M-L-A-I-E-H-V-N-Y-Q-F-N-P-S-P-F-A-T-C-D-L-F-V-T-F-P-A-W-A-P-L-N-Q-W-A-P-N-L-F-E-A-Y-G-D-C-S-K-V-V-W-Q-F-L-T-L-S-M-P-Q-W-L-V-V-I-F-A-A-N-L-L-A-L-A-I-F-V-V-A-Q-L-A-K-T-S-R"} +{"text": "### FUNCTION Exports L-alanine ### SEQUENCE -M-K-A-R-G-P-F-C-I-R-H-A-A-A-D-T-F-A-M-V-V-F-C-F-V-T-G-M-I-I-E-I-F-V-S-G-M-T-F-Q-Q-S-L-A-S-R-T-L-S-I-P-V-N-I-A-I-A-W-P-Y-G-V-F-R-D-Y-V-L-R-Q-G-R-K-I-S-P-T-G-W-M-K-N-L-S-D-L-V-A-Y-V-L-F-Q-S-P-V-Y-A-A-I-L-F-T-V-G-A-S-T-D-Q-I-I-T-A-V-A-T-N-A-L-V-S-C-G-M-G-V-L-Y-G-Y-F-L-D-M-C-R-R-W-F-K-V-P-G-Y-T-V-S-E-G"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-Q-L-L-D-F-I-P-L-I-I-F-F-A-L-Y-K-F-Y-D-I-Y-V-A-T-G-A-L-I-A-A-T-T-V-Q-V-I-V-T-Y-A-M-Y-K-K-V-E-K-M-Q-L-I-T-F-V-M-V-A-L-F-G-G-M-T-L-A-L-H-D-D-N-F-I-K-W-K-V-T-I-V-Y-V-V-F-A-L-G-L-T-I-S-Q-I-M-G-K-P-A-I-K-G-M-L-G-K-E-L-T-L-P-D-A-V-W-S-T-I-N-W-A-W-V-M-F-F-S-G-C-A-A-L-N-L-Y-V-A-Y-H-L-P-L-D-V-W-V-N-F-K-V-F-G-L-L-A-A-T-L-V-F-T-L-L-T-G-G-Y-I-Y-K-H-L-P-H-E-P-K-Q-K-N-Q"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-K-F-E-A-V-L-R-T-D-L-G-K-G-A-S-R-R-L-R-N-T-G-Y-F-P-A-I-V-Y-G-G-E-A-A-P-V-S-I-S-L-N-H-D-D-V-M-N-Q-M-D-K-P-E-F-Y-E-A-I-V-L-V-I-D-G-Q-E-V-K-V-K-P-Q-D-V-Q-R-H-A-Y-K-P-K-V-E-H-M-D-F-I-R-I"} +{"text": "### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-S-I-S-T-Q-I-T-F-F-E-F-L-T-P-L-V-A-S-G-Q-K-T-I-T-I-R-D-K-S-E-S-H-Y-V-P-G-T-R-V-E-V-F-T-L-E-T-Q-R-K-V-C-E-I-D-I-L-A-V-E-P-L-K-F-D-E-I-N-E-F-H-A-E-Q-E-A-I-E-L-P-K-L-K-A-L-I-Q-E-I-Y-P-N-I-D-E-L-Y-V-I-T-Y-Q-L-A-K"} +{"text": "### FUNCTION Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ ### SEQUENCE -M-L-K-P-S-D-K-W-S-W-Y-F-S-D-S-E-G-Y-L-M-L-N-L-G-D-D-M-L-F-R-T-N-L-S-R-N-L-L-V-D-C-A-F-I-E-N-P-F-T-V-D-D-A-S-D-F-Q-L-Y-K-E-H-I-A-C-L-P-L-S-E-P-R-K-A-E-L-A-L-Y-C-V-A-A-K-R-F-H-K-P-V-Q-P-K-S-W-F-F-D-V-Q-G-T-G-Y-T-P-Q-Q-G-Q-L-I-S-L-R-N-S-L-N-S-G-I-F-I-A-L-E-V-G-E-N-A-T-L-C-A-Y-S-D-L-V-S-F-A-L-N-G-S-K-T-L-E-F-G-Q-V-I-K-V-M-H-D-R-M-S-D-V-N-T-L-L-Y-T-P-Q-M-A-M-V-S"} +{"text": "### FUNCTION Required for spatial organization of the terminus region of the chromosome during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-Q-L-E-N-L-E-C-G-W-K-W-Q-Y-L-I-N-K-W-K-D-G-E-P-V-T-R-Y-I-D-K-S-E-I-E-A-A-V-Q-K-L-R-A-I-E-H-E-P-T-H-V-L-S-W-I-E-E-H-M-S-S-E-L-D-N-K-L-K-Q-A-I-R-A-K-R-K-R-H-F-N-A-E-Q-I-H-T-R-K-K-S-I-D-L-D-Y-R-V-W-E-K-L-S-L-K-A-N-E-L-G-C-T-L-S-D-A-I-E-Y-L-L-S-E-A-S-R-S-E-K-A-S-K-T-V-N-S-L-K-E-D-L-S-R-L-L-A-E"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-E-L-A-E-A-L-F-E-Q-L-G-M-S-K-R-D-A-K-D-T-V-E-V-F-F-E-E-I-R-K-A-L-E-S-G-E-Q-V-K-L-S-G-F-G-N-F-D-L-R-D-K-N-E-R-P-G-R-N-P-K-T-G-E-D-I-P-I-T-A-R-R-V-V-T-F-R-P-G-Q-K-L-K-A-R-V-E-N-I-K-V-E-K"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-F-V-V-I-F-G-R-P-G-C-P-Y-C-V-R-A-K-E-H-A-E-T-L-K-A-K-R-D-D-F-N-Y-R-Y-V-D-I-H-A-E-G-I-T-K-A-D-L-E-K-T-I-G-K-P-V-E-T-V-P-Q-I-F-I-D-E-Q-H-I-G-G-C-T-D-F-E-A-Y-A-K-E-N-L-G-L-F-D"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-K-N-F-E-W-I-S-P-D-F-D-L-L-E-K-E-K-T-A-V-K-P-P-S-M-Y-H-V-V-L-N-N-D-D-Y-T-P-M-D-F-V-I-E-I-L-E-R-F-F-S-M-D-I-E-R-A-T-Q-V-M-L-K-V-H-Y-E-G-K-A-I-C-G-T-F-T-A-E-V-A-E-T-K-V-A-Q-V-T-M-Y-S-R-E-N-E-H-P-L-L-C-T-M-E-Q-A"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-R-T-S-H-M-L-E-H-L-M-E-A-L-R-C-L-P-G-V-G-P-K-S-A-Q-R-M-A-F-H-L-L-Q-R-D-R-K-G-G-L-Q-L-A-E-A-L-S-Q-A-M-V-E-I-G-H-C-Q-E-C-R-T-F-T-E-Q-D-V-C-H-I-C-S-N-P-K-R-K-E-N-G-Q-L-C-V-V-E-S-P-A-D-I-A-A-L-E-A-T-G-Q-F-S-G-R-Y-F-V-L-M-G-H-L-S-P-L-D-G-I-G-P-S-D-I-G-L-D-T-L-D-Y-R-L-Q-R-G-D-I-S-E-V-I-L-A-T-N-P-T-V-E-G-E-A-T-A-Q-Y-I-A-E-L-C-R-E-H-Q-V-T-A-S-R-I-A-H-G-V-P-V-G-G-E-L-E-L-V-D-G-T-T-L-S-H-S-L-L-G-R-H-K-L-F"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-G-G-M-G-N-L-M-K-Q-A-Q-Q-M-Q-E-R-M-Q-K-L-Q-E-E-I-A-N-M-E-V-T-G-E-S-G-A-G-L-V-K-V-T-V-T-G-S-H-S-V-R-R-V-N-I-D-E-S-L-M-E-D-D-K-E-M-L-E-D-L-I-A-A-A-F-N-D-A-A-R-R-I-E-E-T-Q-K-E-K-M-A-S-I-T-G-G-M-Q-L-P-P-G-M-K-M-P-F"} +{"text": "### FUNCTION Phosphorelay protein which receives sensory signals from a sensory kinase and transmit them to LuxO At low cell density, a phosphoryl group is transferred from the sensory kinase, probably on His-57 and this phosphoryl group is further transferred to LuxO ### SEQUENCE -M-R-E-W-I-N-Q-S-K-I-D-L-L-A-K-E-I-G-E-E-N-V-P-I-L-V-N-I-F-L-G-E-L-N-D-Y-Q-S-K-L-V-S-D-T-V-A-D-K-L-G-Y-L-K-E-I-S-H-A-L-K-S-S-A-A-S-F-G-A-D-R-L-C-A-K-A-V-E-L-D-S-R-A-K-S-G-E-M-M-D-I-S-L-E-V-E-H-M-L-E-L-L-K-Q-T-H-Q-C-Y-S-D-L-V-H"} +{"text": "### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-T-E-Y-L-L-L-L-I-G-T-V-L-V-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-L-E-T-A-I-G-M-G-L-A-T-T-F-V-L-T-L-A-S-V-C-A-Y-L-V-E-S-Y-V-L-R-P-L-G-I-E-Y-L-R-T-M-S-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-V-V-H-K-T-S-P-T-L-Y-R-L-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-I-N-E-N-H-N-F-I-Q-S-I-I-Y-G-F-G-A-A-V-G-F-S-L-V-L-I-L-F-A-S-M-R-E-R-I-H-V-A-D-V-P-A-P-F-K-G-A-S-I-A-M-I-T-A-G-L-M-S-L-A-F-M-G-F-T-G-L-V-K-L"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-Y-E-K-Q-V-E-I-T-A-E-N-G-L-H-T-R-P-A-A-Q-F-V-K-E-A-K-A-F-D-A-D-I-T-V-T-S-N-G-K-S-A-S-A-K-S-L-F-K-L-Q-T-L-G-L-V-K-G-T-V-V-T-I-S-A-E-G-P-Q-A-K-E-A-V-E-H-L-V-A-L-M-D-Q-L-H"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-I-E-L-D-L-Q-L-A-V-E-N-E-H-G-L-P-S-E-A-E-F-A-L-W-L-T-R-T-I-T-P-F-Q-A-Q-A-E-V-T-V-R-I-V-D-E-A-E-S-H-A-L-N-L-N-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-A-P-S-G-M-E-M-D-L-L-G-D-L-V-I-C-R-Q-V-V-E-R-E-A-I-E-Q-N-K-P-L-Q-A-H-W-A-H-M-V-V-H-G-S-L-H-L-L-G-Y-D-H-I-E-D-D-E-A-E-E-M-E-S-L-E-T-E-I-M-Q-E-M-G-F-T-D-P-Y-L-A-E-K-E"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-K-I-Q-L-I-A-V-G-T-K-M-P-K-W-V-E-E-G-F-Q-E-Y-R-R-R-F-P-H-D-M-P-L-E-L-V-E-I-T-A-G-K-R-G-K-N-A-D-I-A-R-I-L-Q-K-E-G-E-A-M-L-A-A-V-P-K-G-N-R-I-V-T-L-D-I-P-G-K-R-W-D-T-E-E-L-A-V-Q-L-E-S-W-K-L-D-G-R-D-V-S-I-L-I-G-G-P-E-G-L-A-P-A-C-K-A-A-A-D-Q-S-W-S-L-S-P-L-T-L-P-H-P-L-V-R-V-V-M-A-E-S-L-Y-R-A-W-S-I-T-T-N-H-P-Y-H-R-E"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-T-Q-S-V-V-Q-A-L-S-A-F-S-Q-R-F-L-Q-H-C-A-Q-Q-T-G-Q-L-P-E-N-D-E-L-L-G-L-A-S-P-C-V-V-E-E-L-T-D-V-V-R-W-R-P-V-N-R-E-V-W-A-D-F-S-N-V-E-R-A-I-E-L-T-L-H-E-D-I-K-A-F-Y-A-S-Q-F-S-A-D-M-P-A-Q-W-R-G-R-E-L-T-L-L-Q-V-W-S-E-D-D-F-T-R-L-Q-E-N-I-L-G-H-L-V-M-Q-R-R-L-K-Q-K-P-T-V-F-I-A-T-T-E-D-E-M-A-V-V-S-V-C-N-L-S-G-N-V-I-L-E-K-L-G-T-A-Q-R-E-V-L-T-A-D-L-E-T-F-L-E-Q-L-E-P-K-V-N"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-S-K-K-P-E-N-M-S-F-E-S-T-I-E-E-L-E-Q-L-V-E-Q-L-E-S-G-D-L-A-L-D-E-A-L-R-K-F-E-R-G-I-S-L-A-R-A-G-Q-L-K-L-D-D-A-E-Q-R-V-R-I-L-L-S-N-S-D-D-A-P-L-S-D-F-S-D-V-A-E"} +{"text": "### FUNCTION Transfers 2- of the citrate lyase to yield holo-acyl carrier protein ### SEQUENCE -M-S-H-H-P-D-L-S-V-S-L-D-Q-L-L-L-R-K-E-V-R-V-R-Q-Q-G-E-W-L-K-R-H-S-L-P-L-V-S-F-T-V-N-M-P-G-A-V-K-L-N-A-A-S-Q-T-V-M-D-A-G-M-R-A-I-Q-E-L-C-Q-K-T-G-W-R-Q-V-A-C-Q-L-L-V-E-K-T-G-P-E-A-F-V-V-I-Q-A-P-S-A-S-M-L-K-K-A-M-M-K-I-E-R-E-H-P-L-G-R-L-M-D-L-D-V-I-D-V-D-G-H-I-I-S-R-Q-G-A-Q-L-P-R-R-R-C-L-L-C-E-R-D-A-V-I-C-A-R-S-R-R-H-S-V-E-A-L-L-A-K-I-E-E-M-T-H-D-Y-S-C-C-A"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-K-I-A-H-P-A-F-A-G-T-L-E-S-S-D-L-Q-V-R-I-E-P-N-N-D-G-G-I-E-L-V-L-D-S-T-V-E-Q-Q-F-G-H-A-I-R-Q-V-V-L-H-T-L-D-A-M-Q-V-R-D-A-L-V-T-I-E-D-K-G-A-L-D-C-V-I-R-A-R-V-Q-A-A-V-M-R-A-C-D-V-Q-N-I-E-W-S-Q-L-S"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-Y-F-E-L-F-G-L-P-I-Q-F-E-L-D-G-S-L-L-S-S-Q-F-R-A-L-Q-K-R-F-H-P-D-N-F-A-T-A-S-E-R-D-R-L-M-A-V-Q-Q-A-A-Q-I-N-D-A-Y-Q-T-L-K-D-P-L-R-R-A-E-Y-L-L-S-L-Q-G-I-E-M-N-A-E-Q-Q-T-L-Q-D-P-M-F-L-M-E-Q-M-E-L-R-E-E-L-E-S-V-T-A-C-A-D-P-E-A-A-L-V-A-F-D-T-K-V-T-A-M-Q-R-H-Y-L-A-Q-L-Q-G-Q-L-A-Q-S-E-W-L-A-A-A-D-Q-I-R-K-L-K-F-I-A-K-L-K-N-E-V-E-R-V-E-D-Q-L-L-G"} +{"text": "### FUNCTION Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins ### SEQUENCE -M-R-L-T-S-K-G-R-Y-A-V-T-A-M-L-D-V-A-L-H-S-Q-Q-N-P-V-P-L-A-D-I-S-E-R-Q-G-I-S-L-S-Y-L-E-Q-L-F-S-K-L-R-K-A-G-L-V-A-S-V-R-G-P-G-G-G-Y-R-L-G-M-D-S-Y-A-I-S-I-G-T-V-I-A-A-V-D-E-S-V-D-A-T-K-C-N-G-K-G-D-C-Q-G-G-T-R-C-L-T-H-T-L-W-R-D-L-S-S-R-I-T-D-F-L-N-N-I-T-L-G-E-L-M-M-D-N-E-V-L-E-V-S-D-R-Q-D-L-H-L-A-V-S-Q-R-V-S-Q-N-N-S-N-T-V-T-I-G-A-A-P-F-G-I-N-V-R-S"} +{"text": "### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-V-Q-Q-P-S-F-S-E-W-Q-Q-V-L-D-L-V-K-Q-A-V-Q-Q-E-Q-H-E-M-L-L-T-M-L-M-T-P-D-E-R-E-A-L-V-A-R-V-N-I-V-H-E-L-L-Q-G-E-L-S-Q-R-Q-I-S-Q-M-L-G-V-G-I-A-T-I-T-R-G-S-N-E-L-K-S-R-S-E-D-E-K-A-A-L-A-Q-L-L-M-P-P-P-S-S-E-A"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-G-D-G-Y-R-L-N-V-G-I-V-I-C-N-N-H-G-Q-V-F-W-A-K-R-Y-G-Q-H-S-W-Q-F-P-Q-G-G-I-D-D-G-E-S-P-E-Q-A-M-F-R-E-L-Y-E-E-V-G-L-T-K-K-D-V-K-V-I-A-T-S-R-H-W-L-R-Y-K-L-P-K-R-L-V-R-W-D-S-Q-P-V-C-I-G-Q-K-Q-K-W-F-L-L-R-L-E-C-D-E-S-K-I-N-M-Q-R-G-S-S-P-E-F-D-G-W-R-W-V-S-Y-W-Y-P-V-R-Q-V-V-S-F-K-R-D-V-Y-R-R-A-M-K-E-F-A-S-L-A-M-P-F-K-E-R-K-V-K-G-K-R-N-T-H-R-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-N-A-E-T-K-A-A-I-V-A-E-Y-A-R-C-E-N-D-T-G-S-P-E-V-Q-I-A-L-L-T-A-S-I-N-H-L-Q-G-H-F-Q-A-H-K-G-D-H-H-S-R-R-G-L-L-R-M-V-S-S-R-R-K-L-L-D-Y-L-K-G-K-D-L-S-R-Y-Q-D-L-I-K-R-L-G-L-R-R"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-K-E-F-S-R-T-Q-R-V-A-Q-Q-L-Q-K-E-L-A-M-I-L-Q-R-E-V-R-D-S-R-L-G-M-V-T-I-S-D-V-E-V-S-R-D-L-A-Y-A-K-V-F-V-T-F-L-C-I-G-E-Q-T-P-E-S-C-L-A-A-L-R-E-H-E-V-Q-I-R-M-M-L-G-K-Q-I-R-L-R-L-T-P-E-I-R-F-Y-Y-D-N-T-L-V-E-G-M-R-M-S-N-L-V-T-E-V-I-N-S-D-K-R-R-K-H-E-A-G-R-D-E-D-E-A"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-G-L-E-R-Q-L-T-E-M-L-E-A-P-V-V-A-A-G-Y-E-L-V-G-L-E-F-V-R-A-G-Q-H-S-T-L-R-I-F-I-D-H-E-N-G-I-T-V-E-D-C-A-E-V-S-R-Q-V-S-A-V-L-D-V-E-D-P-I-S-V-V-Y-N-L-E-V-S-S-P-G-L-E-R-P-L-F-K-A-A-H-Y-E-Q-F-I-G-H-E-V-S-I-V-L-K-M-A-V-G-N-R-R-K-W-K-G-V-I-Q-S-I-D-G-E-T-V-A-V-M-V-D-G-Q-E-E-H-F-A-L-S-N-I-S-K-A-N-L-I-P-K-F"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-E-K-V-P-M-T-A-R-G-E-K-L-L-R-E-E-L-D-R-L-L-K-L-R-P-K-I-T-E-A-I-A-E-A-R-E-L-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-E-Q-G-I-C-E-A-Q-I-R-D-I-E-Y-K-L-S-V-A-Q-V-I-D-V-T-K-M-E-N-S-G-K-V-I-F-G-A-T-V-T-V-I-D-V-N-S-D-E-E-K-T-Y-Q-I-V-G-D-D-E-A-D-I-K-S-G-R-I-S-V-N-S-P-I-A-R-G-L-I-G-K-F-E-G-D-E-V-S-I-A-T-P-G-G-N-K-V-F-E-I-D-R-V-E-Y-L"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-E-V-N-V-P-L-S-F-S-D-A-A-A-K-R-V-K-A-L-I-A-E-E-E-N-P-S-L-M-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-T-V-N-E-G-D-T-K-I-E-N-S-G-V-I-L-V-V-D-P-M-S-L-Q-Y-L-I-G-G-V-V-D-Y-T-E-G-L-E-G-S-R-F-F-V-N-N-P-N-A-T-T-T-C-G-C-G-A-S-F-S-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-V-A-K-P-E-T-V-K-R-D-W-Y-V-V-D-A-E-G-K-T-L-G-R-L-A-S-E-I-A-S-R-L-R-G-K-H-K-A-E-Y-T-P-H-V-D-T-G-D-Y-I-I-V-V-N-A-E-K-V-T-V-T-G-N-K-A-K-N-K-M-Y-H-R-H-S-E-F-P-G-G-L-K-S-F-S-F-E-K-L-I-E-R-K-P-E-M-V-L-E-L-A-V-K-G-M-L-P-K-G-P-L-G-R-A-M-Y-R-K-L-K-V-Y-A-G-A-E-H-N-H-A-A-Q-Q-P-K-V-L-D-I"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-N-I-I-K-A-L-E-Q-E-Q-M-K-Q-D-L-P-Q-F-A-P-G-D-T-V-V-V-Q-V-K-V-K-E-G-D-R-E-R-L-Q-A-F-E-G-I-V-I-A-I-R-N-R-G-L-H-S-A-F-T-V-R-K-I-S-N-G-E-G-V-E-R-T-F-Q-T-H-S-P-V-V-D-S-I-E-V-K-R-R-G-A-V-R-R-A-K-L-Y-Y-L-R-D-L-S-G-K-A-A-R-I-K-E-K-L-A-K-K"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-G-K-E-T-M-S-K-Q-N-E-K-L-V-V-G-K-L-G-S-S-Y-G-I-R-G-W-L-K-V-F-S-Y-T-D-N-P-E-S-I-F-D-Y-S-P-W-Y-I-D-Q-K-G-E-W-V-E-Y-K-V-E-G-W-K-R-H-N-K-G-W-V-V-K-L-Q-G-L-D-V-R-E-D-A-H-L-L-T-N-F-E-I-A-I-D-P-A-S-L-P-E-L-S-E-D-E-F-Y-W-R-E-L-F-G-M-Q-V-V-T-T-N-G-Y-D-L-G-V-V-T-D-M-M-E-T-G-S-N-D-V-L-V-V-K-A-N-L-K-D-A-F-G-Q-K-E-R-L-I-P-F-L-E-E-Q-V-I-K-V-V-D-R-Q-A-Q-R-I-E-V-D-W-D-P-A-F"} +{"text": "### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-M-I-G-D-E-V-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-V-N-A-P-K-E-V-S-V-H-R-E-E-I-Y-M-R-I-Q-A-E-K-G-N-G-G-V-A-S-G-N-Y"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-V-F-A-L-T-L-S-L-L-L-V-W-L-L-Y-T-L-M-W-G-K-N-G-V-M-D-F-R-A-V-Q-A-E-I-E-V-Q-Q-Q-V-N-A-N-L-H-L-R-N-Q-E-M-F-A-E-I-D-D-L-R-Q-G-L-D-A-I-E-E-R-A-R-N-E-L-G-M-V-K-D-G-E-T-F-Y-R-I-I-G-E-E-S-R-Q"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-R-T-V-M-A-F-D-Y-G-T-K-S-I-G-S-A-I-G-Q-E-I-T-G-T-A-S-P-L-K-A-F-K-A-N-D-G-I-P-N-W-D-E-I-E-K-Q-I-K-E-W-Q-P-N-L-L-I-V-G-L-P-T-D-L-H-G-K-D-L-D-T-I-T-P-R-A-K-K-F-A-Q-R-L-H-G-R-F-G-L-P-V-E-L-H-D-E-R-L-S-T-T-E-A-R-A-E-L-F-A-M-G-G-Y-K-A-L-S-K-G-N-V-D-C-Q-S-A-V-I-I-L-E-S-W-F-E-S-Q-W-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-T-R-L-Q-K-E-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-C-K-E-A-W-A-Q-W-Q-T-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-D-P-E-H-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-K-E-V-H-I-E-G-Y-T-P-P-A-K"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-S-E-G-Q-T-L-R-L-E-K-L-D-V-E-T-G-A-T-V-E-F-D-K-V-L-L-V-A-N-G-E-D-I-K-V-G-A-P-L-V-E-G-G-K-V-V-A-E-V-V-Q-H-G-R-G-D-K-V-K-I-V-K-F-R-R-R-K-H-S-R-K-Q-Q-G-H-R-Q-W-F-T-E-V-K-I-T-G-I-N-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-R-N-V-D-K-Q-D-N-L-V-R-A-F-K-A-L-L-K-E-E-R-F-G-S-Q-G-D-I-V-E-A-L-K-N-E-G-F-D-N-I-N-Q-S-K-V-S-R-M-L-T-K-F-G-A-V-R-T-R-N-A-K-M-E-M-V-Y-C-L-P-A-E-L-G-V-P-T-A-S-S-S-L-R-E-L-V-L-D-V-D-Y-N-N-A-L-V-V-I-R-T-G-P-G-A-A-Q-L-I-A-R-L-L-D-S-L-G-K-S-E-G-I-L-G-V-V-A-G-D-D-T-I-F-I-T-P-T-L-D-V-P-V-K-E-L-F-H-S-V-C-E-L-F-E-Y-A-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-D-K-I-G-N-L-G-S-L-G-D-T-V-N-V-K-S-G-Y-A-R-N-F-L-I-P-Q-G-K-A-V-M-A-T-K-A-N-V-A-M-F-E-S-R-R-A-E-L-E-A-K-V-A-E-Q-L-A-A-A-Q-T-R-A-D-Q-V-N-A-L-E-A-V-V-I-A-S-K-A-G-D-E-G-K-L-F-G-S-I-G-T-R-D-I-A-D-A-I-T-A-A-G-V-K-V-S-K-S-E-V-R-L-P-E-G-A-L-R-N-V-G-A-Y-E-V-S-V-Q-L-H-S-E-V-F-A-T-A-K-V-Q-V-V-A-E"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-F-F-R-R-R-K-F-C-R-F-T-A-E-G-V-Q-E-I-D-Y-K-D-V-A-T-L-K-N-Y-I-T-E-A-G-K-I-V-P-S-R-I-T-G-T-S-A-K-Y-Q-R-Q-L-A-R-A-I-K-R-A-R-Y-L-A-L-L-P-Y-T-D-K-H-Q"} +{"text": "### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-T-N-R-I-E-L-S-G-V-V-A-K-A-L-V-R-S-Q-S-P-S-G-V-K-H-C-H-F-W-L-E-H-R-S-T-M-V-E-A-D-L-P-R-Q-V-F-C-R-L-P-V-V-V-S-G-A-R-S-E-A-L-T-Q-N-L-V-Q-G-S-S-I-L-V-S-G-F-L-A-Y-Q-T-S-R-N-G-V-G-K-L-V-L-H-A-D-K-I-S-Q-I"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-A-G-M-I-E-R-Y-T-G-S-I-T-E-A-G-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-V-L-M-N-V-E-A-D-Q-A-V-V-D-E-L-E-T-A-F-R-F-N-D-A-V-L-R-N-M-I-M-R-T-K-A-A-I-T-E-P-S-I-M-L-K-A-R-E-E-R-V-K-R-D-E-M-K-F-D-A-D-V-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-I-G-Q-R-K-I-L-P-D-P-K-F-K-S-E-L-L-A-K-F-V-N-I-L-M-V-D-G-K-K-S-T-A-E-K-I-V-Y-T-A-L-D-T-M-A-E-K-S-G-K-D-H-L-A-V-F-E-E-A-L-E-N-V-R-P-A-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-P-V-R-R-N-A-L-A-M-R-W-L-V-E-A-A-R-K-R-G-E-K-S-M-A-A-R-L-A-A-E-M-L-D-A-A-E-N-K-G-S-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-N-Q-L-V-R-K-P-R-A-K-Q-V-V-K-S-N-V-P-A-L-A-A-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-T-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-A-L-D-C-A-G-V-N-D-R-K-Q-A-R-S-K-Y-G-V-K-R-P-K-S"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-K-P-L-T-Y-T-L-V-V-N-G-P-Q-Y-G-T-Q-S-A-R-N-A-Y-L-F-A-K-A-L-I-E-K-G-H-I-L-K-S-V-F-F-Y-Q-D-G-V-L-N-G-S-S-T-H-V-P-A-N-D-E-F-N-L-L-Q-G-W-Q-S-L-A-Q-S-H-Q-V-Q-L-E-T-C-V-A-A-A-L-R-R-G-V-V-S-E-Q-E-A-S-Q-H-G-L-A-S-H-N-L-A-A-H-F-T-Q-A-G-L-G-S-L-A-Q-A-L-L-E-Q-D-R-V-V-Q-F"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-S-F-S-D-Q-N-L-I-W-I-D-L-E-M-T-G-L-D-P-E-M-H-K-I-I-E-M-A-T-I-V-T-D-S-E-L-N-I-L-A-E-G-P-V-I-A-I-H-Q-P-E-S-E-L-A-K-M-D-E-W-C-T-T-T-H-T-A-S-G-L-V-A-R-V-R-Q-S-Q-V-S-E-E-E-A-I-D-Q-T-L-A-F-L-K-Q-W-V-P-E-G-K-S-P-I-C-G-N-S-I-G-Q-D-R-R-F-L-Y-K-H-M-P-R-L-E-A-Y-F-H-Y-R-Y-I-D-V-S-T-I-K-E-L-T-R-R-W-Q-P-E-V-L-K-E-F-S-K-T-G-S-H-L-A-L-D-D-I-R-E-S-I-A-E-L-Q-F-Y-R-K-A-V-F-K-I"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-I-T-N-E-Q-I-L-D-A-I-A-E-M-S-V-M-Q-V-V-E-L-I-S-A-M-E-E-K-F-G-V-S-A-A-A-A-V-V-S-G-P-A-A-A-A-A-V-E-E-Q-T-E-F-N-V-I-L-A-A-A-G-A-N-K-V-A-V-I-K-A-V-R-G-A-T-G-L-G-L-K-E-A-K-A-L-V-D-G-A-P-A-S-V-K-E-A-V-S-K-E-E-A-E-A-L-K-K-E-L-E-E-A-G-A-T-V-E-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-Q-D-K-K-A-I-V-A-E-V-N-E-A-A-S-G-A-L-S-A-V-V-A-D-S-R-G-V-Q-V-A-A-M-T-N-L-R-K-Q-A-R-E-A-G-V-Y-L-K-V-V-R-N-T-L-A-R-R-A-V-E-G-T-A-Y-E-C-L-K-D-V-F-V-G-P-T-L-I-G-F-S-N-E-H-P-G-A-A-A-R-L-F-K-D-F-A-K-E-N-K-A-F-E-I-K-A-A-A-F-E-G-V-L-T-D-P-E-V-L-A-T-L-P-T-Y-D-E-A-I-A-R-L-M-M-C-M-K-E-A-S-A-G-K-L-V-R-T-I-A-A-V-R-D-Q-K-E-A-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-A-Y-V-K-L-Q-V-A-A-G-M-A-N-P-S-P-P-V-G-P-A-L-G-Q-R-G-V-N-I-M-E-F-C-K-A-F-N-A-R-T-E-S-L-E-K-G-L-P-I-P-V-V-I-T-V-Y-S-D-R-S-F-T-F-E-T-K-T-P-P-A-S-V-L-L-K-K-A-A-G-I-K-S-G-S-A-R-P-N-T-A-K-V-G-T-I-T-D-A-Q-I-Q-E-I-A-A-T-K-A-A-D-M-T-G-A-D-I-E-A-M-K-R-S-I-A-G-T-A-R-S-M-G-L-V-V-E-G"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-S-E-A-P-K-K-R-W-Y-V-V-Q-A-F-S-G-F-E-G-R-V-A-Q-S-L-R-E-H-I-K-M-H-G-M-E-E-L-F-G-E-V-L-V-P-T-E-E-V-V-E-M-R-A-G-Q-R-R-K-S-E-R-K-F-F-P-G-Y-V-L-V-Q-M-I-M-N-D-E-S-W-H-L-V-R-S-V-P-R-V-M-G-F-I-G-G-T-S-D-R-P-A-P-I-T-D-K-E-A-D-A-I-L-N-R-L-E-K-A-S-E-A-P-R-P-K-T-M-F-E-A-G-E-V-V-R-V-N-D-G-P-F-A-D-F-N-G-T-V-E-E-V-D-Y-E-K-S-R-L-K-V-S-V-S-I-F-G-R-A-T-P-V-E-L-E-F-G-Q-V-E-K-L-D"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-K-A-N-N-A-E-A-P-D-S-S-N-A-A-D-T-L-K-W-V-A-T-F-V-L-L-V-A-A-V-V-G-N-Y-L-Y-G-E-L-S-V-V-A-R-A-A-G-V-I-V-L-I-A-A-A-L-G-V-A-A-T-T-T-K-G-K-E-A-I-V-F-A-R-E-S-R-M-E-V-R-K-V-V-W-P-T-R-Q-E-T-M-Q-T-T-L-I-V-L-A-V-S-I-V-M-A-L-A-L-W-G-I-D-G-I-M-V-R-L-V-A-F-A-T-G-V"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-Q-L-I-D-F-I-A-E-K-A-D-L-T-K-V-Q-A-K-A-A-L-E-A-T-L-G-A-V-E-G-A-L-K-D-G-D-Q-V-Q-L-I-G-F-G-T-F-K-V-N-H-R-S-A-R-T-G-R-N-P-K-T-G-E-E-I-K-I-A-A-A-N-V-P-A-F-V-A-G-K-A-L-K-D-A-I-K"} +{"text": "### FUNCTION Represses the transcription of several genes encoded within the Vibrio 7th pandemic island-1 , including dncV, VC_0176, VC_0178 and VC_0180 ### SEQUENCE -M-R-R-S-M-K-I-S-A-E-M-Y-K-L-L-I-E-R-T-L-D-G-F-S-V-I-E-L-R-D-E-F-I-V-I-K-D-S-L-I-D-P-D-E-A-Y-K-K-V-Y-R-Q-I-L-R-F-I-K-K-G-W-L-N-G-E-G-S-G-R-Q-K-R-Y-F-Q-T-D-T-F-K-A-L-H-A-E-P-K-S-E-N-V-D-I-E-I-V-L-N-Q-D-Y-S-V-L-V-S-E-R-N-Q-Y-K-G-E-L-E-I-V-L-G-E-I-D-E-Y-Q-S-L-N-I-R-F-P-E-L-E-P-K-L-I-T-L-L-D-E-A-K-E-R-S-A-C-L-L-G-K-V-N-G-L-T-N-V-L-K-V-L-S-G-Q-K-I-V-H-Q-K-F-K-T-K-A-L-L-F-E-R-T"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-E-T-E-F-H-Q-L-V-D-S-Q-L-E-R-I-E-A-A-I-D-E-A-G-A-D-I-D-Y-E-T-S-G-N-V-M-T-L-E-F-D-D-G-S-Q-I-I-I-N-R-Q-E-P-M-R-E-I-W-L-A-S-K-S-G-G-Y-H-F-K-S-I-D-G-E-W-I-C-S-K-T-G-L-E-L-L-T-L-L-K-Q-E-C-D-K-H-A-D-E-P-I-D-W-V"} +{"text": "### FUNCTION A GTPase-activating protein that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-S-R-S-K-K-S-R-K-P-G-T-N-S-N-D-Q-L-V-V-V-R-T-R-S-E-S-E-L-E-S-R-L-R-K-K-L-K-K-R-K-G-L-K-S-G-S-R-H-S-E-G-S-E-S-Q-V-R-Q-A-A-Q-K-R-D-P-R-L-G-S-K-K-P-I-P-L-I-V-A-E-P-K-K-L-N-K-Q-E-R-K-L-A-A-E-Q-E-L-A-M-L-E-K-D-A-Q-L-N-V-L-L-D-R-L-D-N-G-E-K-L-G-I-G-L-Q-K-Y-V-D-E-K-L-D-R-I-E-V-L-M-E-Q-L-G-L-L-D-D-E-P-E-P-A-P-A-P-Q-S-K-P-T-K-K-R-K-T-E-D-D-L-L-S-E-F-E-Q-L-D-V-D-K-Y-Q-D"} +{"text": "### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-D-H-F-L-H-I-D-V-N-A-A-Q-A-M-M-E-Q-K-Q-A-H-L-V-D-I-R-D-P-Q-S-F-Q-L-A-H-A-K-N-A-Y-H-L-T-N-Q-S-M-V-Q-F-M-E-Q-A-E-F-D-Q-P-V-L-V-M-C-Y-H-G-I-S-S-Q-G-A-A-Q-Y-L-V-N-Q-G-F-E-E-V-Y-S-V-D-G-G-F-E-A-W-H-R-A-N-L-P-I-E-A-S"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-S-F-A-I-L-G-F-I-A-L-G-G-A-V-G-A-C-A-R-F-L-V-S-E-I-C-V-T-L-F-G-R-G-F-P-I-G-T-L-T-V-N-V-V-G-S-F-I-M-G-V-L-I-A-C-V-E-N-E-W-L-S-P-Y-P-W-K-Q-V-I-G-L-G-F-L-G-A-L-T-T-F-S-T-F-S-M-D-N-V-L-L-M-Q-Q-G-A-F-F-K-M-G-A-N-V-L-L-N-V-I-L-S-I-S-A-A-W-I-G-F-H-W-L-M-K-S"} +{"text": "### FUNCTION Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide ### SEQUENCE -M-T-V-G-I-I-M-G-S-K-S-D-W-P-T-M-K-H-A-A-E-M-L-D-Q-F-G-V-A-Y-E-T-K-V-V-S-A-H-R-T-P-H-L-L-A-D-Y-A-S-S-A-K-E-R-G-L-Q-V-I-I-A-G-A-G-G-A-A-H-L-P-G-M-T-A-A-F-T-S-L-P-V-L-G-V-P-V-Q-S-R-A-L-S-G-L-D-S-L-Y-S-I-V-Q-M-P-K-G-I-A-V-G-T-L-A-I-G-E-A-G-A-A-N-A-G-L-L-A-A-Q-I-I-G-I-H-N-P-E-V-M-S-K-V-E-A-F-R-A-K-Q-T-Q-S-V-L-D-N-P-N-P-A-E-E"} +{"text": "### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-T-F-N-P-N-I-A-T-H-T-L-E-A-E-G-L-R-C-P-E-P-V-M-M-V-R-K-T-I-R-T-M-L-D-G-E-V-L-L-V-T-A-D-D-P-S-T-T-R-D-I-P-S-F-C-R-F-M-D-H-Q-L-L-G-A-Q-I-D-Q-L-P-Y-Q-Y-L-I-K-K-G-L-A"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-S-T-Y-A-F-N-R-E-L-R-L-L-T-P-E-H-Y-Q-K-V-F-Q-Q-A-H-S-A-G-S-P-H-L-T-I-I-A-R-A-N-N-L-S-H-P-R-L-G-L-A-V-P-K-K-Q-I-K-T-A-V-G-R-N-R-F-K-R-I-C-R-E-S-F-R-L-H-Q-N-Q-L-A-N-K-D-F-V-V-I-A-K-K-S-A-Q-D-L-S-N-E-E-L-F-N-L-L-G-K-L-W-Q-R-L-S-R-P-S-R-G"} +{"text": "### FUNCTION Probable electron transporter required for biotin synthase activity ### SEQUENCE -M-I-H-I-I-T-G-S-T-L-G-G-A-E-Y-V-G-D-H-L-S-D-L-L-Q-E-Q-G-F-D-T-K-I-H-N-Q-P-N-M-S-E-I-P-A-K-G-T-W-L-I-I-T-S-T-H-G-A-G-E-Y-P-D-N-I-Q-P-F-I-Q-A-L-Q-N-T-P-P-N-T-S-A-L-R-Y-A-V-V-A-I-G-D-S-S-Y-D-T-F-C-A-A-G-K-H-A-Y-Q-L-L-G-D-I-G-A-K-P-L-A-N-C-F-T-I-D-V-Q-E-H-P-V-P-E-D-A-A-E-A-W-L-K-R-V-I-N-R-F"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-V-V-I-Y-I-M-S-N-K-Q-G-L-I-I-L-I-S-G-P-S-G-V-G-K-G-T-I-V-S-R-L-L-S-D-N-N-L-K-L-N-V-S-I-S-A-T-T-R-K-K-R-A-S-E-V-E-G-V-H-Y-F-F-K-T-K-E-E-F-E-Q-M-I-A-N-N-Q-L-L-E-Y-A-N-Y-V-N-N-Y-Y-G-T-P-L-S-L-V-K-E-I-L-D-K-N-E-N-L-I-L-E-I-E-Y-Q-G-V-I-Q-V-L-R-K-G-F-R-T-L-S-I-F-V-L-P-P-S-E-D-E-L-V-A-R-L-K-K-R-G-T-E-N-D-E-V-I-K-H-R-L-E-Q-A-V-K-E-Y-A-H-R-E-L-Y-D-H-T-I-I-N-D-D-L-E-K-T-I-E-D-I-K-Q-L-I-L-K-Y-N-Q"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-T-P-E-N-D-Q-A-D-G-P-R-M-R-R-G-R-R-L-A-V-D-V-G-D-A-R-I-G-V-A-S-C-D-P-D-G-I-L-A-T-P-V-E-T-V-P-G-R-D-V-P-A-A-H-R-R-L-R-Q-L-V-A-E-Y-E-P-I-E-V-V-V-G-L-P-R-S-L-K-G-G-E-G-P-A-A-A-K-V-R-R-F-T-Q-E-L-A-K-G-I-A-P-V-P-V-R-L-V-D-E-R-M-T-T-V-T-A-S-Q-G-L-R-A-S-G-V-K-S-K-K-G-R-S-V-I-D-Q-A-A-A-V-I-I-L-Q-Q-A-L-E-S-E-R-V-S-G-R-P-P-G-E-G-V-E-V-V-I"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-T-N-D-L-K-N-G-L-V-L-K-L-E-G-G-Q-L-W-S-V-V-E-F-Q-H-V-K-P-G-K-G-P-A-F-V-R-T-K-L-K-N-V-L-S-G-K-V-V-D-K-T-F-N-A-G-V-K-V-E-T-A-T-V-D-K-R-D-M-Q-F-S-Y-M-D-G-D-Y-F-V-F-M-D-M-E-T-Y-D-Q-L-M-I-D-R-K-V-V-G-D-A-A-N-F-L-V-E-G-F-E-A-T-V-A-Q-H-E-G-E-V-L-F-V-E-L-P-A-A-V-E-L-T-I-Q-E-T-E-P-G-V-Q-G-D-R-S-T-G-G-T-K-P-A-T-L-E-T-G-H-Q-I-N-V-P-L-F-I-T-T-G-E-K-I-K-V-D-T-R-T-S-D-Y-L-G-R-V-N-S"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-A-A-R-N-T-A-R-K-R-A-F-Q-I-L-F-E-G-D-Q-R-G-A-D-V-L-T-V-L-A-D-W-V-R-H-S-R-S-D-T-R-Q-P-P-V-S-E-Y-T-M-E-L-V-E-G-Y-A-G-R-A-E-R-I-D-E-L-I-A-Q-Y-S-V-D-W-T-L-D-R-M-P-V-V-D-R-N-I-L-R-L-G-A-Y-E-L-L-W-V-D-A-T-P-D-A-V-V-L-D-E-M-V-Q-L-A-K-E-F-S-T-D-E-S-P-A-F-I-N-G-L-L-G-R-L-K-E-L-K-P-S-L-R-R-E"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-D-K-Q-Q-D-Q-Q-Q-E-A-R-P-V-L-E-G-P-D-I-A-R-V-L-T-R-I-A-H-E-I-V-E-R-A-K-G-A-D-D-V-V-L-L-G-I-P-T-R-G-V-F-L-A-R-R-L-A-D-K-L-E-Q-I-T-E-R-K-M-P-V-G-S-L-D-I-T-M-Y-R-D-D-L-R-M-H-P-P-R-A-L-A-R-T-E-I-P-G-D-G-I-D-G-R-L-V-V-L-V-D-D-V-L-F-S-G-R-T-I-R-A-A-L-D-A-L-N-D-I-G-R-P-R-A-V-Q-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-L-P-T-S-L-R-E-T-V-K-V-Q-L-A-E-E-D-G-R-D-T-V-L-L-G-A-K-P-A-A-P-G-A-H-P"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-T-T-Q-S-E-R-L-R-E-L-L-E-P-L-V-A-S-Q-G-L-D-L-E-E-I-A-V-D-S-V-G-R-R-R-V-L-S-V-V-V-D-S-D-T-G-A-D-L-D-R-I-A-D-V-S-R-A-L-S-A-K-L-D-E-T-D-A-M-G-E-G-E-Y-T-L-E-V-G-T-P-G-A-E-R-S-L-T-Q-H-R-H-Y-V-R-A-T-D-R-L-V-R-F-Q-L-R-E-G-G-E-L-V-A-R-I-L-A-V-D-E-D-G-L-D-L-E-V-P-G-V-K-G-R-R-P-T-T-R-R-L-P-F-G-D-I-D-K-A-R-V-Q-V-E-F-N-R-K-D-T-K-N-D-N-Q-T-E-H-D-N-K-T-E-E-E-E-A"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-T-T-T-T-P-R-L-K-T-K-Y-R-E-E-I-A-G-K-L-R-E-E-F-S-Y-E-N-V-M-Q-I-P-G-L-V-K-I-V-V-N-M-G-V-G-D-A-A-R-D-S-K-L-I-E-G-A-I-R-D-L-T-T-I-T-G-Q-K-P-A-V-T-K-A-R-K-S-I-A-Q-F-K-L-R-E-G-Q-P-I-G-A-H-V-T-L-R-G-D-R-M-W-E-F-L-D-R-T-L-S-L-A-L-P-R-I-R-D-F-R-G-L-S-P-K-Q-F-D-G-R-G-N-Y-T-F-G-L-T-E-Q-V-M-F-H-E-I-D-Q-D-K-I-D-R-T-R-G-M-D-I-T-V-V-T-T-A-T-N-D-A-E-G-R-A-L-L-R-H-L-G-F-P-F-K-E-A"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-I-K-K-G-D-L-V-Q-V-I-T-G-K-D-K-G-K-Q-G-K-V-I-A-A-F-P-R-E-D-R-V-L-V-E-G-V-N-R-V-K-K-H-T-K-A-G-P-T-A-R-G-S-Q-A-G-G-I-V-T-T-E-A-P-I-H-V-S-N-V-Q-L-V-V-E-K-D-G-N-K-V-V-T-R-V-G-Y-R-F-D-D-E-G-N-K-V-R-V-A-K-R-T-G-E-D-I"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-R-V-A-D-N-T-G-A-K-E-I-L-T-I-R-V-L-G-G-S-G-R-R-Y-A-G-I-G-D-V-I-V-A-T-V-K-D-A-I-P-G-G-N-V-K-K-G-D-V-V-K-A-V-I-V-R-T-V-K-E-R-R-R-P-D-G-S-Y-I-R-F-D-E-N-A-A-V-I-L-K-N-D-G-D-P-R-G-T-R-I-F-G-P-V-G-R-E-L-R-E-K-K-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-S-N-V-T-E-E-T-K-A-A-R-G-F-R-K-T-R-Q-G-L-V-V-S-D-K-M-D-K-T-V-V-V-A-V-E-D-R-V-T-H-A-L-Y-G-K-V-I-R-R-T-E-K-L-K-A-H-D-E-Q-N-A-A-G-V-G-D-R-V-L-L-M-E-T-R-P-L-S-A-T-K-R-W-R-V-V-E-V-L-E-K-A-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-I-P-R-R-V-K-H-R-K-Q-H-H-P-K-R-R-G-M-A-K-G-G-T-Q-V-A-F-G-E-Y-G-I-Q-A-L-T-P-A-Y-V-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-H-I-K-R-G-G-K-V-W-I-N-I-Y-P-D-R-P-L-T-K-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-W-W-I-A-N-V-H-P-G-R-V-M-F-E-L-S-Y-P-N-E-K-I-A-R-E-A-L-T-R-A-A-H-K-L-P-M-K-C-R-I-V-K-R-E-A-G-E-A"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-R-A-Q-A-R-Y-I-R-V-T-P-M-K-A-R-R-V-V-D-L-I-R-G-M-D-A-T-E-A-Q-A-V-L-R-F-A-P-Q-A-A-S-V-P-V-G-K-V-L-D-S-A-I-A-N-A-A-H-N-Y-D-H-T-D-A-D-S-L-F-I-S-E-A-Y-V-D-E-G-P-T-L-K-R-F-R-P-R-A-Q-G-R-A-Y-R-I-R-K-R-T-S-H-I-T-V-V-V-S-S-K-E-G-T-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-V-D-D-H-L-I-K-K-V-D-T-Q-N-E-A-G-T-K-N-V-I-K-T-W-S-R-R-S-M-I-V-P-A-M-L-G-H-T-I-A-V-H-N-G-K-T-H-I-P-V-F-V-T-E-S-M-V-G-H-K-L-G-E-F-S-P-T-R-T-F-R-G-H-V-K-D-D-R-K-S-K-R-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-A-P-K-R-P-V-I-I-D-P-V-Y-G-S-P-L-V-T-S-L-I-N-K-V-L-L-N-G-K-R-S-T-A-E-R-I-V-Y-G-A-M-E-G-L-R-E-K-T-G-N-D-P-V-I-T-L-K-R-A-L-E-N-I-K-P-T-L-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-I-E-V-K-P-G-R-A-N-T-L-A-L-R-W-L-V-G-Y-S-R-A-R-R-E-K-T-M-T-E-R-L-L-N-E-L-L-D-A-S-N-G-L-G-A-A-V-K-K-R-E-D-T-H-K-M-A-E-S-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-R-S-G-G-R-Q-H-K-V-A-V-G-D-I-V-E-V-D-K-I-S-T-G-K-V-G-D-T-V-E-L-S-T-L-L-V-V-D-G-D-A-V-T-S-D-P-W-V-L-A-G-I-K-V-Q-A-E-I-V-D-H-H-K-G-Q-K-I-D-I-L-R-Y-K-N-K-T-G-Y-R-R-R-Q-G-H-R-Q-Q-Y-T-A-I-K-V-T-E-I-P-A-A-A-K"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-E-K-G-R-K-L-I-A-Q-N-K-K-A-R-H-D-Y-Q-I-L-D-T-Y-E-A-G-L-V-L-S-G-T-E-V-K-S-L-R-Q-G-R-A-S-L-A-D-G-F-V-Q-L-D-G-H-E-A-W-L-H-N-V-H-V-P-E-Y-S-Q-G-T-W-T-N-H-S-A-R-R-K-R-K-L-L-L-H-R-V-E-I-D-K-L-E-S-K-S-Q-E-T-G-H-T-I-V-P-L-A-L-Y-F-K-D-G-R-A-K-V-E-I-A-L-A-R-G-K-K-E-Y-D-K-R-Q-T-L-R-E-K-Q-D-R-R-E-A-E-R-T-I-S-A-I-K-R-K-Q-R-A"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-I-D-V-N-N-E-S-G-T-E-V-D-E-Q-A-I-L-D-I-A-R-Y-A-L-A-R-M-R-I-H-P-L-S-E-L-S-V-I-V-V-D-A-E-A-M-E-Q-L-H-I-Q-W-M-D-L-P-G-P-T-D-V-M-S-F-P-M-D-E-L-R-P-P-S-K-D-E-E-E-A-P-Q-G-L-L-G-D-I-V-L-C-P-E-V-A-A-K-Q-G-A-E-A-P-T-E-H-S-M-D-E-E-L-Q-L-L-T-V-H-G-V-L-H-L-L-G-Y-D-H-E-E-P-D-E-K-A-E-M-F-G-L-Q-A-A-I-V-D-G-W-R-A-E-K-G-L-T-G-P-S-P-A-P-T-V-S"} +{"text": "### FUNCTION Required for coenzyme pyrroloquinoline quinone ### SEQUENCE -M-A-W-N-T-P-K-V-T-E-I-P-L-G-A-E-I-N-S-Y-V-C-G-E-K-K"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-S-R-S-I-M-G-F-D-Y-G-T-K-S-I-G-V-A-I-G-Q-E-L-T-G-T-G-Q-P-L-R-A-I-K-A-N-D-G-I-P-N-W-D-D-I-D-K-L-L-K-E-W-Q-P-D-L-L-V-V-G-L-P-L-N-M-D-G-T-E-Q-E-I-T-V-R-A-R-K-F-G-N-R-L-H-G-R-F-W-Q-A-V-E-F-K-D-E-R-L-T-T-T-D-A-R-A-R-L-F-E-R-G-G-Y-R-A-L-E-K-G-S-V-D-G-V-S-A-Q-L-I-L-E-A-W-M-E-E-Q-Y-G"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-A-T-Q-K-K-P-D-L-S-D-P-T-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-V-F-P-I-V-I-M-G-S-F-A-C-I-V-A-L-A-V-L-D-P-A-M-T-G-E-P-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-L-Y-P-V-F-Q-I-L-R-S-L-P-N-K-L-L-G-V-L-A-M-A-S-V-P-L-G-L-I-L-V-P-F-I-E-N-V-N-K-F-Q-N-P-F-R-R-P-V-A-T-T-V-F-L-F-G-T-L-V-T-L-W-L-G-I-G-A-A-L-P-L-D-K-S-L-T-L-G-L-F"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-R-A-P-M-T-S-K-G-A-Q-R-L-R-E-E-L-D-H-L-K-S-V-K-R-P-A-V-I-T-A-I-A-E-A-R-A-H-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-Q-Q-S-F-I-E-G-R-I-K-Q-L-E-G-E-L-S-H-A-E-I-I-D-I-T-K-L-A-A-G-T-K-I-V-F-G-A-T-V-T-L-A-D-T-E-T-D-E-E-K-R-Y-Q-I-V-G-D-L-E-A-D-I-K-L-G-L-I-A-I-S-S-P-L-A-R-A-L-I-G-K-L-E-G-D-S-V-T-I-D-A-P-A-G-Q-R-E-Y-E-V-V-S-V-A-Y-L-D"} +{"text": "### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide operon in response to exogenous pyrimidines, probably by binding to specific sites on pyr mRNA This probably disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-A-R-K-E-I-I-D-E-I-T-M-K-R-A-I-T-R-I-T-Y-E-I-I-E-R-N-K-E-L-D-K-L-V-L-I-G-I-K-T-R-G-V-Y-L-A-K-R-I-Q-E-R-L-Q-Q-L-E-G-L-E-I-P-F-G-E-L-D-T-R-P-F-R-D-D-K-Q-A-Q-E-D-T-T-E-I-D-I-D-I-T-G-K-D-V-I-L-V-D-D-V-L-Y-T-G-R-T-I-R-A-A-I-D-G-I-V-K-L-G-R-P-A-R-V-Q-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-G-H-D-E-E-I-I-V-Q-M-S-E-H-D-G-N-D-S-I-L-I-K-R-E-D"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-P-I-G-V-P-S-V-P-Y-R-L-P-G-S-S-F-E-R-W-I-D-I-Y-N-R-L-A-M-E-R-I-I-F-L-G-Q-E-V-T-D-G-L-A-N-S-I-V-A-Q-L-L-Y-L-D-S-E-D-S-S-K-P-I-Y-L-Y-I-N-S-P-G-G-S-V-T-A-G-M-A-I-Y-D-T-M-Q-Y-I-K-S-P-V-I-T-I-C-L-G-L-A-A-S-M-G-A-F-L-L-C-A-G-S-K-G-K-R-L-A-L-P-H-S-R-I-M-I-H-Q-P-L-G-G-T-G-R-R-Q-A-S-D-I-E-I-E-A-K-E-I-L-R-I-K-K-L-L-N-Q-I-M-A-D-R-T-G-Q-P-L-E-K-I-E-K-D-T-D-R-D-Y-F-M-S-A-E-E-A-R-E-Y-G-L-I-D-Q-V-I-A-E-R-P-V"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-E-Q-N-T-N-H-E-S-P-E-Q-N-V-A-H-D-N-I-E-H-S-D-S-I-L-E-E-T-M-K-E-F-D-P-Q-H-N-S-G-E-E-M-T-I-E-N-E-I-D-L-D-T-F-K-A-R-I-A-E-L-E-G-E-V-K-E-A-K-E-G-T-A-R-A-N-A-E-A-Y-D-A-Q-K-R-M-E-Q-E-A-D-K-S-K-K-F-A-L-Q-K-F-A-R-E-L-L-E-I-V-D-N-L-E-R-A-I-E-N-A-D-A-N-D-P-V-A-E-G-V-Q-L-T-H-K-A-L-L-A-V-L-H-K-N-G-I-E-V-V-D-P-Q-G-E-K-F-N-A-D-L-H-E-A-V-D-I-D-A-E-A-E-A-D-T-V-G-T-V-L-Q-K-G-Y-S-L-N-G-R-L-L-R-P-A-M-V-R-V-G-Q"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-D-I-E-S-I-V-E-K-L-S-S-L-T-L-I-Q-A-A-E-L-S-K-R-L-E-E-E-W-G-V-S-A-S-A-P-V-A-A-V-A-P-A-V-X-X-D-V-A-V-A-E-K-T-E-F-E-V-F-L-E-S-F-D-A-K-S-K-I-S-V-I-K-E-V-R-S-I-T-D-L-G-L-K-E-A-K-E-L-V-E-A-L-L-K-S-L-R-T-G-V-S-K-D-E-A-N-E-L-K-K-K-L-E-A-A-G-A-T-I-S-L-R"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-N-R-Q-E-K-S-V-E-I-S-E-L-S-K-I-L-S-S-S-G-S-V-V-V-A-H-Y-K-G-I-S-V-A-Q-I-R-T-S-K-E-G-X-R-E-A-G-G-G-V-K-V-X-X-N-R-L-V-K-I-A-V-R-D-T-S-V-K-E-V-S-D-L-F-V-G-Q-S-L-I-V-Y-S-V-D-P-I-V-A-P-K-I-S-V-N-F-A-N-D-N-K-Q-F-V-V-L-G-G-V-L-E-N-D-V-L-D-Q-C-S-I-K-Q-I-A-S-L-P-N-I-D-G-I-R-A-I-I-I-S-A-I-Q-F-N-A-T-K-L-L-R-L-L-S-A-P-Q-A-Q-V-V-R-A-L-S-A-F-V-D-K-N-K-Q-S"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-S-N-K-K-E-I-V-V-T-D-W-I-K-Q-N-C-H-E-G-N-F-L-N-L-T-L-S-S-D-Q-R-R-V-F-R-G-K-R-K-S-D-C-N-Q-E-L-Q-L-Q-L-P-R-E-G-K-L-N-D-G-D-I-L-L-T-N-Q-K-K-L-F-V-Q-I-I-A-Q-K-E-N-L-I-K-I-T-A-K-T-S-I-E-L-I-K-V-A-Y-H-L-G-N-R-H-V-E-I-E-I-N-E-N-I-L-F-T-K-S-D-Y-I-I-E-E-L-L-R-N-F-D-V-V-Y-S-K-V-E-K-K-F-F-P-E-I-G-A-F-H-H-E-K-K-S-L-S"} +{"text": "### FUNCTION Probable electron transporter required for biotin synthase activity ### SEQUENCE -M-K-T-K-I-C-I-I-T-G-S-T-L-G-G-A-E-Y-V-A-E-H-I-A-E-I-L-E-Q-Q-D-Y-P-V-R-L-E-H-G-P-N-F-E-E-V-I-D-E-K-C-W-L-V-V-T-S-T-H-G-A-G-E-L-P-D-N-I-K-P-L-F-E-K-L-A-F-H-P-K-Q-L-A-D-L-R-F-A-V-I-G-L-G-N-S-D-Y-D-T-F-C-H-A-V-D-H-V-E-Q-L-L-L-S-K-D-A-L-Q-L-C-E-S-L-R-M-D-M-L-T-I-T-D-P-E-H-T-A-E-Q-W-L-P-Q-F-L-S-Q-L"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-L-S-F-F-K-T-L-S-T-K-R-S-A-W-F-L-L-F-S-S-A-L-L-L-E-A-I-A-L-Y-F-Q-H-G-M-G-L-A-P-C-V-M-C-I-Y-E-R-V-A-I-L-G-I-A-F-S-G-L-L-G-L-L-Y-P-S-S-M-L-L-R-L-V-A-L-L-I-G-L-S-S-A-I-K-G-L-M-I-S-I-T-H-L-D-L-Q-L-Y-P-A-P-W-K-Q-C-S-A-V-A-E-F-P-E-T-L-P-L-D-Q-W-F-P-A-L-F-L-P-S-G-S-C-S-E-V-T-W-Q-F-L-G-F-S-M-V-Q-W-I-V-V-I-F-A-L-Y-T-L-L-L-A-L-I-F-I-S-Q-V-K-R-L-K-P-K-Q-R-R-L-F-H"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-T-I-N-T-N-N-L-T-I-T-I-S-A-A-S-K-K-Q-Y-P-E-N-D-W-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-L-L-N-R-K-N-F-A-R-T-S-G-Q-P-G-K-T-Q-L-L-N-F-Y-N-I-D-D-Q-L-H-F-V-D-V-P-G-Y-G-Y-A-R-V-S-K-K-E-R-E-K-W-G-K-M-I-E-E-Y-L-T-T-R-E-N-L-K-A-V-V-S-L-V-D-I-R-H-E-P-S-E-D-D-L-M-M-Y-E-F-L-K-Y-Y-H-I-P-V-I-L-V-A-T-K-A-D-K-V-P-R-G-K-W-N-K-H-E-S-I-I-K-K-A-M-K-F-D-S-T-D-D-F-I-I-F-S-S-T-D-K-T-G-I-E-E-A-W-T-A-I-L-K-Y-L"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-L-P-A-R-N-R-M-T-R-S-T-E-F-D-A-T-V-K-H-G-T-R-M-A-Q-P-D-I-V-V-H-L-R-R-G-S-E-P-D-D-E-S-A-G-P-R-V-G-L-V-V-G-K-A-V-G-T-A-V-Q-R-H-R-V-A-R-R-L-R-H-V-A-R-P-L-L-G-E-L-Q-P-S-D-R-L-V-I-R-A-L-P-G-S-R-T-V-S-S-A-R-L-A-Q-E-L-Q-R-C-L-R-R-M-P-A-G-S-G-R"} +{"text": "### FUNCTION Binds zinc Could be an important component of the zinc-balancing mechanism ### SEQUENCE -M-K-R-N-N-K-S-A-I-A-L-I-A-L-S-L-L-A-L-S-S-G-A-A-F-A-G-H-H-W-G-N-N-D-G-M-W-Q-Q-G-G-S-P-L-T-T-E-Q-Q-A-T-A-Q-K-I-Y-D-D-Y-Y-T-Q-T-S-A-L-R-Q-Q-L-I-S-K-R-Y-E-Y-N-A-L-L-T-A-S-S-P-D-T-A-K-I-N-A-V-A-K-E-M-E-S-L-G-Q-K-L-D-E-Q-R-V-K-R-D-V-A-M-A-Q-A-G-I-P-R-G-A-G-M-G-Y-G-G-C-G-G-Y-G-G-G-Y-H-R-G-G-G-H-M-G-M-G-N-W"} +{"text": "### FUNCTION Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase ### SEQUENCE -M-L-N-Q-L-E-N-L-T-E-R-V-G-G-S-N-K-L-V-D-R-W-L-D-V-R-K-H-L-L-V-A-Y-Y-N-L-V-G-I-K-P-G-K-E-S-Y-M-R-L-N-E-K-A-L-D-D-F-C-Q-S-L-V-D-Y-L-S-A-G-H-F-S-I-Y-E-R-I-L-H-K-L-E-G-N-G-Q-L-L-H-A-A-K-I-W-P-L-L-E-D-N-T-Q-R-I-M-D-Y-Y-D-T-S-L-E-T-A-I-D-H-D-N-C-L-E-F-Q-Q-A-L-S-D-I-G-E-A-L-E-A-R-F-V-L-E-D-K-L-I-M-L-V-F-D-A-M-H-D-G-A-R-V-K-R-P-A"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-A-Q-L-V-D-A-I-A-A-K-A-D-L-S-K-A-Q-A-K-V-A-L-E-E-I-I-N-G-I-T-Q-S-L-K-E-G-D-A-V-Q-L-V-G-F-G-T-F-K-V-N-H-R-A-G-R-T-G-R-N-P-Q-T-G-K-E-I-Q-I-A-A-A-N-V-P-S-F-V-A-G-K-A-L-K-D-A-V-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-P-K-K-K-K-K-V-T-G-L-I-K-L-Q-I-Q-A-G-Q-A-N-P-A-P-P-V-G-P-A-L-G-A-H-G-V-N-I-M-E-F-C-K-A-Y-N-A-A-T-E-N-Q-R-G-N-V-V-P-V-E-I-T-V-Y-E-D-R-S-F-D-F-K-L-K-T-P-P-A-A-K-L-L-L-K-A-A-G-L-Q-K-G-S-G-V-P-H-T-Q-K-V-G-K-V-S-M-A-Q-V-R-E-I-A-E-T-K-K-E-D-L-N-A-R-D-I-D-A-A-A-K-I-I-A-G-T-A-R-S-M-G-I-T-V-E-G"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-E-E-K-L-T-Q-D-P-T-A-E-E-E-Q-T-E-T-A-D-Q-Q-E-S-A-D-V-N-W-E-Q-E-A-A-H-W-K-A-Q-A-E-E-H-Q-N-R-M-L-R-T-M-A-D-M-E-N-L-R-R-R-V-R-K-E-Q-E-D-L-A-K-Y-A-S-Q-K-V-V-E-E-L-L-P-I-L-D-N-F-E-R-A-L-A-A-D-K-E-S-M-T-V-E-S-L-L-T-G-V-D-M-V-Y-R-Q-M-V-Q-V-F-D-K-E-G-L-V-A-I-A-A-K-G-Q-P-F-D-P-H-V-H-Q-A-V-M-Q-T-Q-D-P-A-F-E-S-G-V-V-V-E-E-L-Q-K-G-Y-M-F-K-D-R-V-V-R-P-A-M-V-K-V-N-E"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -A-I-I-P-K-Q-F-L-K-R-I-E-R-T-G-F-G-Q-F-L-F-Y-E-W-R-F-D-E-A-G-N-I-N-P-E-F-E-P-N-K-P-R-Y-A-G-A-S-V-L-I-S-R-A-N-F-G-C-G-S-S-R-E-H-A-P-W-A-I-M-D-Y-G-F-R-C-V-I-A-P-S-F-A-D-I-F-Y-N-N-C-F-K-N-G-I-L-P-I-K-L-S-E-E-Q-V-E-D-L-F-Q-R-T-A-K-H-D-N-Y-Q-L-N-V-D-L-N-E-K-T-I-T-D-D-Y-G-L-R-I-E-F-D-L-D-E-H-R-R-Q-F-L-L-Q-G-L-D-D-I-G-L-T-L-Q-H-E-S-E-I-L-A-Y-E-Q-K-R-A-A-K-Q-G-A"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-R-S-L-L-L-A-V-C-L-V-L-A-L-H-C-G-E-A-A-V-S-C-N-T-V-I-A-D-L-Y-P-C-L-S-Y-V-T-Q-G-G-P-V-P-T-L-C-C-N-G-L-T-T-L-K-S-Q-A-Q-T-S-V-D-R-Q-G-V-C-R-C-I-K-S-A-I-G-G-L-T-L-S-P-R-T-I-Q-N-A-L-E-L-P-S-K-C-G-V-D-L-P-Y-K-F-S-P-S-T-D-C-D-S-I-Q"} +{"text": "### FUNCTION Cell signaling peptide that may regulate plant stress, growth, and development Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca ### SEQUENCE -M-S-I-L-K-E-T-K-R-F-M-V-V-A-M-F-I-A-C-V-F-I-S-N-N-M-N-V-A-V-A-N-E-I-G-Y-P-G-M-G-R-G-D-R-Q-P-G-C-D-H-G-N-C-P-P-D-Q-P-A-N-P-Y-H-R-G-C-E-K-S-K-R-C-R-G-P-D-P-P-A-L-P-R-K-M-I"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-A-S-A-N-P-E-T-A-K-P-T-P-A-T-V-D-M-A-N-P-E-E-L-K-K-V-F-D-Q-F-D-S-N-G-D-G-K-I-S-V-L-E-L-G-G-V-F-K-A-M-G-T-S-Y-T-E-T-E-L-N-R-V-L-E-E-V-D-T-D-R-D-G-Y-I-N-L-D-E-F-S-T-L-C-R-S-S-S-S-A-A-E-I-R-D-A-F-D-L-Y-D-Q-D-K-N-G-L-I-S-A-S-E-L-H-Q-V-L-N-R-L-G-M-S-C-S-V-E-D-C-T-R-M-I-G-P-V-D-A-D-G-D-G-N-V-N-F-E-E-F-Q-K-M-M-T-S-S-S-L-L-N-S-N-G-S-A-A-P-P-S-T"} +{"text": "### FUNCTION Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione ### SEQUENCE -M-A-S-Q-S-T-D-Q-P-K-S-I-H-D-F-I-V-K-D-A-R-G-N-D-V-D-L-S-I-Y-K-G-K-V-L-L-I-V-N-V-A-S-Q-C-G-L-T-N-S-N-Y-P-E-L-T-K-L-Y-E-Q-Y-K-D-K-G-L-E-I-L-A-F-P-C-N-Q-F-G-N-Q-E-P-G-D-N-E-Q-I-M-E-F-A-C-T-R-F-K-A-E-F-P-I-F-D-K-V-D-V-N-G-S-N-A-A-P-V-Y-K-Y-L-K-S-S-K-G-G-L-F-G-D-G-I-K-W-N-F-T-K-F-L-V-D-R-D-G-K-V-V-D-R-Y-A-P-T-T-S-P-A-S-I-E-K-D-I-K-K-L-I-G-T-S"} +{"text": "### FUNCTION Acts redundantly with SPR1 in maintaining the cortical microtubules organization essential for anisotropic cell growth ### SEQUENCE -M-G-K-A-R-G-V-N-S-G-G-G-E-S-S-L-G-Y-L-F-G-S-G-E-S-V-P-K-P-N-K-P-N-A-K-T-G-F-T-T-T-T-T-T-T-T-T-T-D-G-A-G-G-R-P-K-T-T-T-T-T-T-T-T-G-D-K-N-K-T-E-E-N-S-A-G-V-R-G-S-P-N-N-Y-Y-R-S-D-G-Q-N-C-G-N-F-L-T-E-R-P-S-T-K-V-H-A-A-P-G-G-G-S-S-L-G-Y-L-F-G-S-G-P-C-G-S-D-K"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-A-D-A-T-E-K-A-E-H-D-R-I-F-K-K-F-D-A-N-G-D-G-K-I-S-A-A-E-L-E-E-A-L-K-T-L-G-S-V-T-A-D-D-V-K-R-M-M-A-E-I-D-T-D-G-D-G-N-I-S-Y-Q-E-F-T-D-F-A-G-A-N-R-G-L-M-K-D-V-A-K-I-F"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-S-V-A-E-I-F-E-R-V-D-K-N-K-D-G-K-I-S-W-D-E-F-A-E-A-I-R-A-F-S-P-S-I-T-S-E-E-I-D-N-M-F-R-E-I-D-V-D-G-D-N-Q-I-D-V-A-E-Y-A-S-C-L-M-L-G-G-E-G-N-K-E-D-E-D-I-V-M-K-E-A-F-D-L-Y-D-I-D-G-D-G-K-I-S-A-S-E-I-H-V-V-L-K-R-L-G-E-K-Q-T-I-A-E-C-I-A-M-V-R-A-V-D-A-D-G-D-G-F-V-S-F-E-E-F-K-T-M-M-S-C-N-N-K-K-L-Q"} +{"text": "### FUNCTION Controls stomatal patterning ### SEQUENCE -M-F-A-I-Y-K-S-T-L-L-L-L-P-L-I-L-I-L-L-I-T-P-Q-V-S-S-F-L-Q-P-I-Q-P-P-I-S-P-Q-V-A-L-I-E-D-K-A-R-L-G-S-T-P-P-S-C-H-N-R-C-N-N-C-H-P-C-M-A-I-Q-V-P-T-L-P-T-R-S-R-F-T-R-V-N-P-F-S-G-G-F-V-R-P-P-S-S-L-T-T-V-L-D-Q-Y-S-N-Y-K-P-M-G-W-K-C-H-C-N-G-H-F-Y-N-P"} +{"text": "### FUNCTION Component of the chloroplast ribosome , a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus ### SEQUENCE -M-A-V-Q-A-N-Q-S-A-S-F-G-F-R-T-A-S-P-S-Q-K-L-S-S-K-P-I-A-H-I-S-L-S-T-K-L-K-P-S-S-R-P-S-L-S-C-S-T-W-N-Q-G-Q-I-P-A-R-H-S-C-I-N-P-G-I-F-A-Y-P-P-S-N-L-T-F-S-H-E-L-P-E-S-E-S-P-P-L-G-K-K-K-M-R-V-L-V-K-P-L-E-K-P-K-V-V-L-K-F-V-W-M-Q-K-D-I-G-V-A-L-D-H-M-I-P-G-F-G-T-I-P-L-S-P-Y-Y-F-W-P-R-K-D-A-W-E-E-L-K-T-L-L-E-S-K-P-W-I-S-E-L-H-R-V-F-L-L-N-Q-A-T-D-I-I-N-L-W-Q-S-S-G-G-D-L-S"} +{"text": "### FUNCTION Essential component of the signal peptidase complex ### SEQUENCE -M-H-S-W-V-Q-R-L-L-T-T-A-T-T-A-A-L-L-L-L-A-A-C-C-A-A-S-A-L-D-A-F-H-V-P-S-V-Q-A-Q-A-H-V-T-K-I-N-R-F-H-K-Q-L-N-G-N-D-K-V-F-V-F-L-T-A-E-Y-E-N-S-K-N-S-L-N-Q-V-S-L-W-D-H-I-I-P-D-K-D-K-A-N-L-Q-V-E-V-K-S-K-Y-P-L-I-D-Q-G-S-S-L-R-G-K-K-V-Q-L-V-L-H-W-H-V-M-P-K-A-G-V-M-I-R-D-R-M-A-L-S-E-F-N-L-P-D-S-Y-T-S"} +{"text": "### FUNCTION Cell signaling peptide that may regulate plant stress, growth, and development Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca ### SEQUENCE -M-T-K-T-F-F-S-F-S-F-F-F-T-S-S-L-L-L-L-L-A-A-T-S-A-T-A-S-T-G-N-V-T-S-G-L-R-Y-D-G-C-A-P-G-D-T-V-G-E-C-I-T-A-T-V-E-E-E-D-E-E-G-V-E-A-V-V-R-R-I-L-Q-Q-R-K-Y-L-S-Y-K-T-L-Q-K-Q-P-T-C-D-G-R-I-A-G-N-C-I-G-T-V-N-P-K-G-A-T-C-T-Y-Y-Q-R-C-K-R-A-A"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-A-A-P-F-A-L-R-K-I-G-V-P-P-N-S-A-N-L-T-E-A-R-R-R-V-F-D-F-F-R-A-A-C-R-S-I-P-T-I-M-D-I-Y-N-L-Q-D-V-V-A-P-S-Q-L-R-Y-A-I-S-A-Q-I-R-N-N-A-H-I-T-D-P-K-V-I-D-L-L-I-F-K-G-M-E-E-L-T-D-I-V-D-H-A-K-Q-R-H-H-I-I-G-Q-Y-V-V-G-E-G-L-V-Q-N-T-G-N-K-D-Q-G-K-T-D-F-L-K-N-F-Y-T-S-N-Y-F"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-I-D-D-Q-D-L-G-F-I-A-N-F-L-G-I-F-I-F-A-L-V-I-A-Y-H-Y-V-T-A-D-P-K-Y-E-A-T"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-A-S-T-K-P-T-D-Q-I-K-Q-L-K-D-I-F-A-R-F-D-M-D-K-D-G-S-L-T-Q-L-E-L-A-A-L-L-R-S-L-G-I-K-P-R-G-D-Q-I-S-L-L-L-N-Q-I-D-R-N-G-N-G-S-V-E-F-D-E-L-V-V-A-I-L-P-D-I-N-E-E-V-L-I-N-Q-E-Q-L-M-E-V-F-R-S-F-D-R-D-G-N-G-S-I-T-A-A-E-L-A-G-S-M-A-K-M-G-H-P-L-T-Y-R-E-L-T-E-M-M-T-E-A-D-S-N-G-D-G-V-I-S-F-N-E-F-S-H-I-M-A-K-S-A-A-D-F-L-G-L-T-A-S"} +{"text": "### FUNCTION Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters ### SEQUENCE -M-S-E-G-S-E-D-T-K-T-K-L-D-S-A-G-E-L-S-D-V-D-N-E-N-C-S-S-S-G-S-G-G-G-S-S-S-G-D-T-K-R-T-C-V-D-C-G-T-I-R-T-P-L-W-R-G-G-P-A-G-P-K-S-L-C-N-A-C-G-I-K-S-R-K-K-R-Q-A-A-L-G-M-R-S-E-E-K-K-K-N-R-K-S-N-C-N-N-D-L-N-L-D-H-R-N-A-K-K-Y-K-I-N-I-V-D-D-G-K-I-D-I-D-D-D-P-K-I-C-N-N-K-R-S-S-S-S-S-S-N-K-G-V-S-K-F-L-D-L-G-F-K-V-P-V-M-K-R-S-A-V-E-K-K-R-L-W-R-K-L-G-E-E-E-R-A-A-V-L-L-M-A-L-S-C-S-S-V-Y-A"} +{"text": "### FUNCTION Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism ### SEQUENCE -M-A-K-L-I-L-I-I-V-T-Q-I-L-L-I-A-A-V-V-S-A-R-K-G-E-N-F-A-K-T-I-D-K-K-H-F-G-L-R-K-E-K-L-T-H-F-R-V-Y-W-H-D-I-L-S-G-S-N-P-S-S-V-V-I-N-P-P-I-S-N-S-S-F-F-G-S-V-T-V-I-D-N-R-L-T-T-E-V-A-V-N-S-T-L-V-G-Q-A-Q-G-I-Y-A-A-T-G-Q-R-D-A-S-A-L-M-V-M-N-F-A-F-K-T-G-K-Y-N-G-S-S-I-A-I-L-G-R-N-A-V-L-T-K-V-R-E-M-P-V-I-G-G-S-G-L-F-R-F-A-R-G-Y-V-E-A-R-T-M-W-F-D-Q-K-S-G-D-A-T-V-E-Y-S-C-Y-V-L-H-Y"} +{"text": "### FUNCTION May function as positive regulator of plant growth ### SEQUENCE -M-A-N-P-N-E-W-S-Q-F-Y-N-N-N-Q-T-F-F-T-T-S-T-T-A-S-T-A-V-T-T-T-T-A-G-D-T-T-S-I-D-S-R-L-S-P-E-T-G-R-V-T-K-P-T-R-R-R-S-R-A-S-R-R-T-P-T-T-L-L-N-T-D-T-S-N-F-R-A-M-V-Q-Q-Y-T-G-G-P-S-A-M-A-F-G-S-G-N-T-T-S-A-F-S-L-T-S-S-S-D-P-S-A-G-S-S-Q-Q-A-P-W-Q-Y-N-F-Q-P-H-A-P-L-Q-P-P-Q-R-P-Y-M-F-S-L-N-N-V-N-P-V-V-G-Y-S-N-M-N-N-P-N-T-M-V-S-G-V-F-G-T-V-D-G-S-G-G-G-G-S-A-P-S-S-K-E-A-T-N-S-N-S-S-S-S-R-L-Q"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-E-E-I-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-Q-E-L-T-Q-E-Q-I-M-E-F-K-E-A-F-C-L-F-D-K-D-G-D-G-C-I-T-A-D-E-L-A-T-V-I-R-S-L-D-Q-N-P-T-E-Q-E-L-Q-D-M-I-T-E-I-D-S-D-G-N-G-T-I-E-F-S-E-F-L-N-L-M-A-N-Q-L-Q-E-T-D-A-D-E-E-L-K-E-A-F-K-V-F-D-K-D-Q-N-G-Y-I-S-A-S-E-L-R-H-V-M-I-N-L-G-E-K-L-T-D-E-E-V-D-Q-M-I-K-E-A-D-L-D-G-D-G-Q-V-N-Y-D-E-F-V-R-M-M-M-I-N-G"} +{"text": "### FUNCTION May be involved in free fatty acids export ### SEQUENCE -M-H-D-F-C-F-T-I-P-Y-G-M-L-L-I-G-G-G-F-I-G-Y-M-K-K-G-S-I-T-S-F-A-G-G-A-G-T-G-L-L-L-I-L-A-G-Y-I-S-L-K-A-F-E-K-K-K-N-S-T-I-A-M-V-L-Q-T-V-I-A-A-A-L-T-L-V-M-G-Q-R-Y-L-L-T-G-K-I-M-P-A-G-L-V-A-G-I-S-A-L-M-T-C-F-Y-V-Y-K-I-A-T-G-G-N-K-F-P-A-K-A-E"} +{"text": "### FUNCTION Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs ### SEQUENCE -M-V-Q-L-L-F-K-F-L-I-Q-V-G-A-T-F-V-E-L-S-R-N-E-I-G-N-K-N-L-L-L-L-I-H-H-A-G-S-L-L-L-S-M-F-G-S-F-S-N-Y-P-V-Q-K-F-L-D-M-L-D-E-R-C-L-T-L-I-A-S-E-F-D-S-Y-F-E-N-L-V-K-D-R-V-G-N-Y-V-V-Q-R-L-I-W-G-F-K-R-T-G-I-D-L-P-H-S-L-T-S-V-L-V-T-R-S-I-H-L-C-K-H-R-Y-G-Y-Q-V-I-E-A-F-D-R-S-T-R-L-A"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-A-F-A-L-R-F-F-T-C-L-V-L-T-V-C-I-V-A-S-V-D-A-A-I-S-C-G-T-V-A-G-S-L-A-P-C-A-T-Y-L-S-K-G-G-L-V-P-P-S-C-C-A-G-V-K-T-L-N-S-M-A-K-T-T-P-D-R-Q-Q-A-C-R-C-I-Q-S-T-A-K-S-I-S-G-L-N-P-S-L-A-S-G-L-P-G-K-C-G-V-S-I-P-Y-P-I-S-M-S-T-N-C-N-N-I-K"} +{"text": "### FUNCTION Potential transcription factor that plays a central role during developmental processes ### SEQUENCE -M-E-Q-E-S-L-N-G-R-Y-G-S-R-V-M-T-D-E-Q-M-E-T-L-R-K-Q-I-A-I-Y-A-V-L-C-D-Q-L-V-F-L-H-N-S-L-S-S-V-P-L-L-S-S-G-M-N-P-M-R-G-E-Y-F-D-P-M-V-A-S-S-S-A-H-G-M-S-T-R-P-R-W-T-P-T-T-T-Q-L-Q-I-L-E-N-I-Y-K-E-G-S-G-T-P-N-P-R-R-I-K-E-I-T-M-E-L-S-E-H-G-Q-I-M-E-K-N-V-Y-H-W-F-Q-N-R-R-A-R-S-K-R-K-Q-P-P-T-T-T-I-T-S-S-Q-A-D-D-A-A-V-T-T-T-E-E-R-G-R-C-G-D-D-S-G-G-F-E-S-Y-E-H-I-L-F-P-S-P-D-L-G-I-E-H-L-L-N-R-D-K-F-I-D"} +{"text": "### FUNCTION May act as a carbohydrate transporter ### SEQUENCE -M-A-Q-S-S-G-H-V-S-Y-V-A-V-T-V-P-I-A-I-V-M-T-V-L-C-L-F-L-A-N-A-V-T-Y-A-R-R-P-T-T-Y-I-V-G-G-D-D-G-W-D-P-V-V-P-M-D-T-W-A-R-G-K-T-F-Y-A-G-D-I-L-E-F-K-Y-D-Y-Q-R-F-N-L-I-V-V-N-R-T-G-Y-E-T-C-E-A-N-V-G-A-I-E-Y-S-S-G-D-D-K-I-Q-L-N-Y-G-Y-N-Y-F-I-G-T-Y-T-P-E-D-C-T-T-G-L-K-M-A-I-K-A-L-A-P-R"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-D-P-T-E-L-K-R-V-F-Q-M-F-D-K-N-G-D-G-T-I-T-G-K-E-L-S-E-T-L-R-S-L-G-I-Y-I-P-D-K-E-L-T-Q-M-I-E-K-I-D-V-N-G-D-G-C-V-D-I-D-E-F-G-E-L-Y-K-T-I-M-D-E-E-D-E-E-E-E-D-M-K-E-A-F-N-V-F-D-Q-N-G-D-G-F-I-T-V-D-E-L-K-A-V-L-S-S-L-G-L-K-Q-G-K-T-L-D-D-C-K-K-M-I-K-K-V-D-V-D-G-D-G-R-V-N-Y-K-E-F-R-Q-M-M-K-G-G-G-F-N-S-L"} +{"text": "### FUNCTION This protein binds directly to 23S ribosomal RNA ### SEQUENCE -M-A-S-L-S-T-S-V-V-A-S-A-S-S-R-L-W-N-P-A-A-S-N-G-K-I-C-V-P-S-A-S-L-S-L-R-T-G-C-R-R-S-S-S-S-L-T-S-S-A-S-S-Q-L-L-H-C-S-F-L-S-S-P-V-S-L-A-S-P-F-S-G-L-S-I-A-F-D-L-S-S-Q-T-S-G-L-N-G-Q-R-R-R-G-L-V-V-R-A-G-K-A-A-L-C-Q-T-K-R-S-R-S-R-K-S-L-A-R-T-H-G-F-R-R-R-M-R-T-T-S-G-R-A-T-I-K-R-R-R-A-K-G-R-W-N-L-C-P-K-S-N-P-S-S-G-K-R-A"} +{"text": "### FUNCTION Heavy-metal-binding protein ### SEQUENCE -M-E-V-P-M-D-C-P-G-C-E-N-K-V-R-K-A-L-E-K-M-N-G-V-H-D-V-Q-I-D-I-K-Q-Q-R-V-T-V-T-G-S-A-E-Q-K-K-V-L-K-V-A-R-N-V-T-K-R-D-I-C-L-W-S-Y-P-Y-H-P-E-S-N-G-Y-N-D-R-Y-F-K-K-K-F-R-K-R-I-N-M-S-V-N-G-E-K-V-S-S-Y-N-Y-H-K-H-G-Y-H-G-H-E-H-G-Y-Y-Q-E-R-P-Y-S-G-L-I-N-P-S-A-S-S-M-F-S-E-E-N-P-H-F-C-S-I-M"} +{"text": "### FUNCTION This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport This protein may be one of the heme-binding subunits of the oxidase ### SEQUENCE -M-S-S-A-Q-M-D-P-H-D-K-M-R-S-R-D-I-S-K-V-A-R-G-Q-Q-A-P-R-P-A-H-T-P-G-T-V-S-P-P-P-E-N-E-A-T-F-R-A-K-R-G-D-S-G-R-E-T-D-A-A-V-E-E-R-F-P-V-T-N-E-T-R-H-C-F-N-R-F-M-Q-Y-H-K-C-I-E-K-N-G-R-D-A-N-D-C-N-N-L-R-D-Y-V-R-S-I-C-P-E-E-L-V-S-K-I-W-L-K-S-G-R-N-K-E-S-Q-G-H-Y-Q-R-Q-Y-E-D"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-D-C-S-F-I-T-T-N-D-L-R-R-M-F-K-T-L-D-K-N-Q-D-G-L-V-T-L-D-E-L-L-W-I-L-D-K-L-G-W-A-E-H-T-P-D-E-L-E-L-I-V-G-K-Q-S-L-D-L-D-E-F-L-R-F-Y-Y-D-A-V-L-D-S-K-G-S-K-K-N-I-D-V-V-A-D-N-D-E-A-I-A-R-A-F-N-V-F-D-V-N-G-D-G-Y-I-S-A-E-E-L-R-D-V-L-E-R-L-G-F-E-E-E-A-K-A-W-D-C-G-R-M-I-R-V-H-D-K-N-L-D-G-F-V-D-F-E-E-F-K-N-M-I-L-H-V"} +{"text": "### FUNCTION Probably acts as a transcriptional activator Binds to the GCC-box pathogenesis-related promoter element May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways ### SEQUENCE -M-E-N-T-Y-V-G-Q-R-D-Y-R-F-N-V-N-Q-L-S-Y-R-G-I-R-R-R-K-W-G-K-W-V-S-E-I-R-E-P-G-K-K-T-R-I-W-L-G-S-Y-E-T-A-E-M-A-A-A-A-Y-D-A-A-A-L-H-L-R-G-R-G-T-N-L-N-F-P-E-L-V-D-S-F-P-R-P-E-S-S-S-S-E-H-I-Q-A-A-A-Q-D-A-A-L-M-F-K-P-G-R-L-S-E-P-A-L-E-S-G-Q-G-L-S-R-V-G-L-S-P-D-Q-I-Q-A-I-N-E-S-P-L-D-S-P-R-M-G-W-M-Q-D-L-E-V-A-D-Y-E-E-L-Y-G-Q-F-F-G-Q-H-D-R-D-E-F-F-E-M-Q-Q-F-Q-S-I-W-N-S-N-N"} +{"text": "### FUNCTION Probable transcription factor involved in somatic embryogenesis Acts as positive regulator of BHLH109 ### SEQUENCE -M-F-Y-T-N-M-E-T-V-H-N-C-F-N-D-A-T-I-T-G-D-E-I-I-D-I-L-A-F-L-Q-S-D-E-S-D-N-P-S-G-I-N-E-V-V-P-V-D-D-K-K-R-R-R-T-I-S-N-R-E-S-A-K-R-S-R-M-K-K-K-K-R-F-E-E-L-T-E-E-V-N-R-L-N-I-R-N-Q-E-L-K-N-R-L-A-N-V-V-S-C-G-N-F-I-S-R-E-N-N-R-L-K-T-E-S-V-C-L-E-I-R-L-L-E-L-Y-R-F-L-V-A-M-Q-S-P-I-S-T-S-V-N-Y-I-T-T-L-E-I"} +{"text": "### FUNCTION Actin-depolymerizing protein Severs actin filaments and binds to actin monomers ### SEQUENCE -M-A-N-S-A-S-G-M-H-V-S-D-E-C-K-L-K-F-L-E-L-K-A-K-R-N-Y-R-F-I-V-F-K-I-D-E-K-A-Q-Q-V-M-I-D-K-L-G-N-P-E-E-T-Y-E-D-F-T-R-S-I-P-E-D-E-C-R-Y-A-V-Y-D-Y-D-F-T-T-P-E-N-C-Q-K-S-K-I-F-F-I-A-W-S-P-D-T-S-R-V-R-S-K-M-L-Y-A-S-S-K-D-R-F-K-R-E-L-D-G-I-Q-V-E-L-Q-A-T-D-P-S-E-M-S-L-D-I-I-K-G-R-V-N-L"} +{"text": "### FUNCTION May be involved in the regulation of ethylene receptor signaling Promotes cell expansion and plant growth ### SEQUENCE -M-A-I-F-G-K-L-T-K-L-K-S-A-I-K-K-W-P-S-L-T-K-N-H-H-S-T-M-C-T-A-S-T-A-V-S-E-V-S-K-C-E-D-L-H-V-V-Y-V-G-K-S-R-R-P-Y-M-L-S-S-H-V-I-A-H-P-L-F-Q-E-L-L-D-R-S-S-R-F-I-E-E-R-H-D-Q-E-T-V-L-V-A-C-E-V-V-L-F-E-H-L-L-W-M-L-K-N-S-S-S-D-H-G-D-E-D-D-R-E-R-G-S-V-E-E-L-A-E-F-Y-T-Y"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-S-H-K-V-S-K-K-L-D-E-E-Q-I-N-E-L-R-E-I-F-R-S-F-D-R-N-K-D-G-S-L-T-Q-L-E-L-G-S-L-L-R-A-L-G-V-K-P-S-P-D-Q-F-E-T-L-I-D-K-A-D-T-K-S-N-G-L-V-E-F-P-E-F-V-A-L-V-S-P-E-L-L-S-P-A-K-R-T-T-P-Y-T-E-E-Q-L-L-R-L-F-R-I-F-D-T-D-G-N-G-F-I-T-A-A-E-L-A-H-S-M-A-K-L-G-H-A-L-T-V-A-E-L-T-G-M-I-K-E-A-D-S-D-G-D-G-R-I-N-F-Q-E-F-A-K-A-I-N-S-A-A-F-D-D-I-W-G"} +{"text": "### FUNCTION Provide a mechanistic link between auxin and plasma membrane H ### SEQUENCE -M-A-M-K-K-A-N-K-L-T-Q-T-A-M-I-K-Q-I-L-K-R-C-S-S-L-G-K-K-Q-S-N-V-Y-G-E-D-E-N-G-S-P-L-N-V-P-K-G-H-F-V-V-Y-V-G-E-N-R-V-R-Y-V-V-P-I-S-F-L-T-R-P-E-F-Q-L-L-L-Q-Q-A-E-E-E-F-G-F-D-H-D-M-G-L-T-I-P-C-E-E-V-V-F-R-S-L-T-S-M-L-R"} +{"text": "### FUNCTION May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins ### SEQUENCE -M-A-S-Q-T-N-K-E-L-F-V-G-G-L-A-R-I-L-K-E-Q-R-Q-V-D-V-R-L-K-A-G-D-S-D-Q-K-G-V-S-I-S-A-H-K-L-V-L-S-A-R-S-E-V-F-K-M-I-L-E-T-E-E-I-K-A-T-T-T-L-D-T-I-T-L-S-E-L-K-H-T-E-L-V-A-L-V-E"} +{"text": "### FUNCTION May be involved in heavy metals transport ### SEQUENCE -M-E-K-Q-W-T-S-G-L-F-S-C-M-E-D-S-E-T-A-C-L-T-C-F-C-P-C-V-T-F-G-R-I-A-D-I-S-D-E-G-R-T-G-C-G-R-C-G-V-F-Y-G-L-I-C-C-V-V-G-L-P-C-L-F-S-C-T-Y-R-T-K-I-R-S-K-F-G-L-P-E-S-P-T-S-D-C-V-T-H-F-F-C-E-C-C-A-L-C-Q-E-H-R-E-L-K-T-R-G-L-D-P-S-I-G-W-S-G-N-M-Q-R-T-M-A-P-P-M-S-Q-Q-M-M-G"} +{"text": "### FUNCTION May be involved in heavy metals transport ### SEQUENCE -M-G-R-P-G-S-Q-P-N-E-A-Q-P-P-P-V-Q-V-Q-P-T-V-N-R-D-N-Q-V-H-S-Q-N-G-A-I-G-Q-A-N-I-Q-T-G-R-P-V-N-N-Q-T-Q-N-L-W-S-S-D-L-F-D-C-M-N-D-S-E-N-A-V-I-T-C-L-A-P-C-V-T-L-G-Q-I-A-E-I-V-D-E-G-A-T-P-C-A-T-G-G-L-L-Y-G-M-I-F-F-I-G-V-P-F-V-Y-S-C-M-F-R-A-K-M-R-N-K-Y-G-L-P-D-A-P-A-P-D-W-I-T-H-L-F-C-E-H-C-A-L-C-Q-E-Y-R-E-L-K-H-R-G-F-D-P-N-I-G-W-A-G-N-V-Q-A-Q-Q-P-V-M-S-P-P-T-G-Q-R-M-M-G"} +{"text": "### FUNCTION May be involved in heavy metals transport ### SEQUENCE -M-G-R-P-V-G-Q-T-N-Q-A-Q-P-S-V-Q-H-T-A-S-P-S-N-K-V-S-H-N-G-G-I-G-K-P-A-N-I-P-T-G-I-P-V-N-Y-Q-Q-T-Q-N-Q-W-S-S-Q-L-F-D-C-M-N-D-S-E-N-A-V-I-T-L-I-A-P-C-V-T-F-G-Q-I-A-E-I-V-D-E-G-A-T-P-C-A-T-A-G-L-L-Y-G-A-L-F-F-T-G-A-S-F-V-Y-S-Y-M-F-R-A-R-I-R-K-K-F-G-L-P-D-A-P-A-P-D-W-I-T-H-L-V-C-M-P-F-A-L-C-Q-E-Y-R-E-L-K-H-H-G-F-D-P-I-L-G-W-A-G-N-V-Q-Q-A-Q-Q-Q-E-M-M-T-P-P-T-G-Q-R-M-M-G"} +{"text": "### FUNCTION Cell signaling peptide that may regulate plant stress, growth, and development Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca ### SEQUENCE -M-K-T-F-M-I-I-L-L-V-I-C-S-I-L-I-V-G-R-V-E-A-N-D-N-K-R-K-Y-L-L-L-D-P-C-L-R-P-N-A-P-P-G-C-H-R-Q-P-Y-K-P-R-T-P-V-N-V-Y-S-R-G-C-T-T-I-N-R-C-R-R-V-Q-N-P"} +{"text": "### FUNCTION Probable heavy-metal-binding protein ### SEQUENCE -M-T-A-K-N-A-V-L-Q-L-S-I-H-E-E-R-T-R-K-K-A-L-V-T-V-S-R-F-S-G-V-T-S-I-T-M-D-K-S-G-K-M-T-I-V-G-E-V-D-V-P-A-V-V-M-K-L-R-K-L-C-N-T-E-I-V-S-V-D-D-V-K-P-P-V-K-K-P-E-P-E-K-P-A-E-S-I-A-Y-P-V-P-M-N-Y-A-Y-Q-F-N-P-A-Y-A-N-S-Y-Y-H-Q-P-Y-G-N-C-R-V-V-D-E-P-N-C-V-I-M"} +{"text": "### FUNCTION Probable heavy-metal-binding protein ### SEQUENCE -M-P-P-M-K-A-V-L-Q-L-S-I-H-E-E-R-I-R-K-K-A-F-V-T-V-S-R-C-P-G-V-T-S-I-T-M-D-D-K-T-G-K-M-T-V-V-G-E-V-D-V-P-V-I-V-M-K-L-R-K-L-C-N-T-E-L-V-S-V-E-V-V-K-P-P-E-K-K-P-E-P-E-K-P-A-P-P-K-P-A-P-A-P-A-K-P-A-E-I-V-A-W-P-V-Q-M-N-N-P-Y-Q-Y-N-P-A-Y-A-N-S-Y-Y-Q-P-Y-G-N-S-R-F-V-T-D-E-S-N-C-V-I-M"} +{"text": "### FUNCTION Probable heavy-metal-binding protein ### SEQUENCE -M-Q-V-V-V-L-K-L-D-V-H-C-E-K-T-K-Q-K-A-M-S-T-V-C-C-L-S-G-V-N-S-V-E-V-K-D-G-K-L-T-V-T-G-E-I-D-A-Y-M-I-V-K-K-L-K-K-I-C-H-T-E-F-I-S-V-G-P-V-K-E-P-E-K-K-K-P-D-D-P-K-K-P-E-T-K-P-P-D-V-I-Y-H-Y-V-P-P-C-P-P-Y-Y-H-N-F-N-G-C-Y-N-E-D-P-N-A-C-V-T-S"} +{"text": "### FUNCTION Probable heavy-metal-binding protein ### SEQUENCE -M-Y-I-N-T-H-D-S-I-F-G-A-G-N-H-K-T-F-T-F-L-Y-I-I-S-L-H-S-S-Y-K-L-F-H-F-L-K-M-Q-Q-N-T-N-V-V-F-K-L-E-V-D-E-R-K-K-K-K-A-M-K-I-V-C-G-F-S-G-V-T-S-L-N-V-M-E-E-G-K-L-T-V-T-G-E-F-D-N-Y-E-M-T-K-K-L-K-K-I-C-K-H-V-A-I-I-A-A-E-P-I-R-E-P-E-Q-N-R-N-P-V-T-R-R-E-P-N-R-E-P-E-Q-N-R-S-R-V-T-R-R-E-P-S-R-E-P-E-P-N-R-A-P-L-A-R-R-E-S-R-P-R-T-H-S-R-P-S-I-P-H-A-R-P-S-R-V-R-G-E-N-S-D-G-C-I-I-M"} +{"text": "### FUNCTION Probable cyclin-dependent protein kinase inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle ### SEQUENCE -M-S-K-I-K-I-F-H-L-F-P-D-D-K-D-I-E-A-T-Q-Q-P-E-S-L-L-V-P-S-K-S-D-S-L-D-S-S-L-S-R-H-H-Q-E-N-Q-S-N-R-Q-R-N-H-Q-H-R-Q-Q-D-Q-E-L-E-N-L-Q-D-G-S-R-G-K-R-K-W-E-C-K-D-E-E-S-P-V-K-I-P-E-T-P-R-N-S-N-S-V-C-Y-C-P-P-R-P-P-R-K-P-K-A-I-P-S-M-K-R-R-G-M-W-V-K-R-S-V-V-F-L-D-V-A-R-E-V-E-S-M-F-P-P-S-V-L-Q-D-F-G-K-K-I-K-K-A-R-F"} +{"text": "### FUNCTION Elicitor of plant defense ### SEQUENCE -M-E-K-L-D-K-R-R-E-E-E-T-Y-L-W-I-P-V-Q-F-L-D-Q-A-L-I-A-V-L-K-C-I-G-L-L-C-Q-P-A-K-K-T-A-P-S-P-V-T-F-N-Q-P-E-E-Q-E-E-D-Y-G-V-A-L-K-D-D-D-V-V-V-L-L-R-D-N-K-A-K-S-K-K-R-D-K-E-K-P-S-S-G-R-P-G-Q-T-N-S-V-P-N-A-A-I-Q-V-Y-K-E-D"} +{"text": "### FUNCTION Part of a three-gene cluster containing FLC, UFC and DFC, which is coordinately regulated in response to vernalization Not regulated by FLX ### SEQUENCE -M-A-K-S-F-V-P-L-I-A-V-L-C-V-L-V-L-P-L-A-A-M-A-V-G-T-P-F-H-I-E-G-S-V-Y-C-D-T-C-R-F-G-F-E-T-I-A-T-Q-Y-I-R-G-A-R-V-R-I-V-C-K-D-R-V-T-L-K-S-E-L-V-G-V-A-V-T-G-P-D-G-K-Y-K-V-A-V-R-G-D-R-Q-D-Q-Q-C-L-A-E-L-V-H-S-P-L-S-R-C-Q-E-A-D-P-G-R-S-T-A-T-V-I-L-T-R-S-N-G-A-A-S-T-R-H-Y-A-N-A-M-G-F-F-R-D-E-P-L-R-G-C-A-A-L-R-K-R-Y-L-A-D-G-D-N-R-A-I"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-P-I-F-Q-W-L-K-R-C-L-C-G-D-T-N-I-T-I-D-Q-A-I-A-L-V-D-E-E-I-A-N-L-R-K-L-E-R-G-Y-Q-T-N-I-R-N-A-E-N-A-R-D-Q-T-N-V-Q-I-E-R-D-S-F-N-D-T-I-R-L-L-Q-A-E-C-N-L-I-N-L-E-I-P-T-L-N-E-E-K-F-A-I-T-R-L-K-S-A-K-H-F-F-G-A-V-S-S-L-K-E-G-K-A-L-E-C-C-K-E-M-I-K-Q-V-D-E-D-G-H-G-R-V-D-Y-K-E-F-L-Q-M-M-K-T-G-D-F-S-N-R"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-V-R-V-F-L-L-Y-N-L-F-N-S-F-L-L-C-L-V-P-K-K-L-R-V-F-F-P-P-S-W-Y-I-D-D-K-N-P-P-P-P-D-E-S-E-T-E-S-P-V-D-L-K-R-V-F-Q-M-F-D-K-N-G-D-G-R-I-T-K-E-E-L-N-D-S-L-E-N-L-G-I-F-M-P-D-K-D-L-I-Q-M-I-Q-K-M-D-A-N-G-D-G-C-V-D-I-N-E-F-E-S-L-Y-G-S-I-V-E-E-K-E-E-G-D-M-R-D-A-F-N-V-F-D-Q-D-G-D-G-F-I-T-V-E-E-L-N-S-V-M-T-S-L-G-L-K-Q-G-K-T-L-E-C-C-K-E-M-I-M-Q-V-D-E-D-G-D-G-R-V-N-Y-K-E-F-L-Q-M-M-K-S-G-D-F-S-N-R-S"} +{"text": "### FUNCTION Probable transcription factor that may be involved in stress responses ### SEQUENCE -M-V-A-R-S-E-E-V-E-I-V-E-D-T-A-A-K-C-L-M-L-L-S-R-V-G-E-C-G-G-G-G-E-K-R-V-F-R-C-K-T-C-L-K-E-F-S-S-F-Q-A-L-G-G-H-R-A-S-H-K-K-L-I-N-S-S-D-P-S-L-L-G-S-L-S-N-K-K-T-K-T-A-T-S-H-P-C-P-I-C-G-V-E-F-P-M-G-Q-A-L-G-G-H-M-R-R-H-R-S-E-K-A-S-P-G-T-L-V-T-R-S-F-L-P-E-T-T-T-V-T-T-L-K-K-S-S-S-G-K-R-V-A-C-L-D-L-D-S-M-E-S-L-V-N-W-K-L-E-L-G-R-T-I-S"} +{"text": "### FUNCTION Modulates the competence to flowering of apical meristems ### SEQUENCE -M-S-G-V-W-V-F-N-N-G-V-I-R-L-V-E-N-P-N-Q-S-G-G-V-S-T-Q-S-H-G-R-R-N-V-L-V-Y-L-P-T-G-E-A-V-S-S-Y-S-S-L-E-Q-I-L-R-S-L-G-W-E-R-Y-F-S-G-D-S-D-L-I-Q-Y-H-K-R-S-S-I-D-L-I-S-L-P-R-D-F-S-K-F-N-S-V-Y-M-Y-D-I-V-V-K-N-P-N-S-F-H-V-R-D-F-N"} +{"text": "### FUNCTION Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events Histone deacetylases act via the formation of large multiprotein complexes ### SEQUENCE -M-A-F-S-M-L-F-T-G-H-A-E-C-V-K-F-V-K-K-F-N-L-P-L-L-V-T-G-G-G-G-Y-T-K-E-N-V-A-R-C-W-T-V-E-T-G-I-L-L-D-T-E-L-P-N-E-I-S-E-N-D-Y-I-K-Y-F-A-P-D-F-S-L-K-I-P-G-G-H-I-E-N-L-N-T-K-S-Y-I-S-S-I-K-V-Q-I-L-E-N-L-R-Y-I-Q-H-A-P-S-V-Q-M-Q-E-V-P-P-D-F-Y-I-P-D-F-D-E-D-E-Q-N-P-D-V-R-V-D-Q-R-S-R-D-K-Q-I-Q-R-D-D-E-Y-F-D-G-D-N-D-N-D-A-S"} +{"text": "### FUNCTION Core component of nucleosome Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling ### SEQUENCE -M-A-R-S-N-Q-T-A-R-K-A-T-G-G-K-A-P-H-F-A-M-R-V-W-Q-H-S-T-P-P-L-K-K-P-Y-R-Y-K-P-G-T-V-A-L-R-E-I-R-K-Y-Q-K-T-T-D-L-V-I-R-K-L-P-F-Q-R-L-V-K-E-I-A-Q-S-L-K-A-D-L-R-F-Q-T-G-A-V-S-A-L-Q-E-A-A-E-A-F-M-V-G-M-F-E-D-T-N-L-C-A-M-H-A-K-R-S-T-I-M-P-K-D-I-Q-L-A-K-R-L-R-G-D-R-V"} +{"text": "### FUNCTION Probable thiol-disulfide oxidoreductase that may be involved in the redox regulation of a number of cytosolic enzymes ### SEQUENCE -M-G-N-R-C-A-R-T-S-C-C-R-K-L-W-S-C-I-C-C-C-S-N-N-N-N-N-S-Y-G-Q-T-R-S-Q-H-G-S-K-G-K-V-H-P-V-S-R-I-E-K-W-E-E-K-I-T-E-A-N-N-H-G-K-I-L-V-V-N-F-S-A-P-W-C-V-P-C-K-K-I-E-P-V-F-R-D-L-A-S-R-Y-P-S-M-I-F-V-T-V-D-V-E-E-L-A-E-F-S-N-E-W-N-V-E-A-T-P-T-V-V-F-L-K-D-G-R-Q-M-D-K-L-V-G-A-E-T-S-E-L-Q-K-K-T-A-A-A-A-D-L-F-L-R-K-P"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-D-K-V-M-R-M-S-S-E-K-G-V-V-I-F-T-K-S-S-C-C-L-C-Y-A-V-Q-I-L-F-R-D-L-R-V-Q-P-T-I-H-E-I-D-N-D-P-D-C-R-E-I-E-K-A-L-V-R-L-G-C-A-N-A-V-P-A-V-F-V-S-G-K-L-V-G-S-T-N-D-V-M-S-L-H-L-S-G-S-L-V-P-L-I-K-P-Y-Q-S-F-H-N"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-E-R-I-R-D-L-S-S-K-K-A-A-V-I-F-T-K-S-S-C-C-M-C-H-S-I-K-T-L-F-Y-E-L-G-A-S-P-A-I-H-E-L-D-K-D-P-E-G-R-E-M-E-R-A-L-R-A-L-G-S-S-N-P-A-V-P-A-V-F-V-G-G-R-Y-I-G-S-A-K-D-I-I-S-F-H-V-D-G-S-L-K-Q-M-L-K-D-A-K-A-I-W-L"} +{"text": "### FUNCTION Essential component of the TIM1723 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane Links the inner and outer membranes ### SEQUENCE -M-D-T-K-K-K-S-K-E-H-G-L-Y-R-I-V-N-A-I-G-Y-A-F-G-A-G-A-V-G-G-S-V-Y-H-F-V-R-G-A-Y-N-S-P-I-G-A-R-Y-V-G-G-T-Q-A-A-S-M-N-A-P-R-L-G-G-T-F-A-V-F-G-G-L-L-S-T-F-D-Y-A-L-V-R-I-R-K-K-E-D-P-W-N-S-I-V-A-G-A-A-T-G-G-V-L-S-I-R-K-G-V-V-A-A-S-T-S-A-V-M-F-G-F-F-L-A-V-L-N-P-P-F-G-S-K"} +{"text": "### FUNCTION Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner ### SEQUENCE -M-A-T-P-M-I-A-G-A-A-V-A-A-A-A-V-A-G-R-Y-G-I-L-A-W-Q-A-F-K-A-R-P-R-V-P-R-M-R-R-F-Y-E-G-G-F-Q-S-S-M-T-R-R-E-A-A-L-I-L-G-V-R-E-S-V-V-A-D-K-V-K-E-A-H-R-R-V-M-V-A-N-H-P-D-A-G-G-S-H-Y-L-A-S-K-I-N-E-A-K-D-M-M-L-G-K-S-N-N-S-G-S-A-F"} +{"text": "### FUNCTION This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport ### SEQUENCE -M-A-G-H-K-V-A-H-A-T-L-K-G-P-S-V-V-K-E-L-I-I-G-L-T-L-G-L-A-A-G-G-L-W-K-M-H-H-W-N-E-Q-R-K-T-R-T-F-Y-D-L-L-E-R-G-E-I-G-V-V-A-S-E-E"} +{"text": "### FUNCTION Actin-depolymerizing protein Severs actin filaments and binds to actin monomers ### SEQUENCE -M-V-L-H-D-D-C-K-L-T-F-L-E-L-K-E-R-R-T-F-R-S-I-V-Y-K-I-E-D-N-M-Q-V-I-V-E-K-H-H-Y-K-K-M-H-G-E-R-E-Q-S-Y-E-E-F-A-N-S-L-P-A-D-E-C-R-Y-A-I-L-D-I-E-F-V-P-G-E-R-K-I-C-F-I-A-W-S-P-S-T-A-K-M-R-K-K-M-I-Y-S-S-T-K-D-R-F-K-R-E-L-D-G-I-Q-V-E-F-H-A-T-D-L-T-D-I-S-L-D-A-I-R-R-R-I-N"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-M-R-V-V-L-P-L-C-L-L-L-A-S-I-F-A-W-G-S-E-A-A-I-S-C-N-A-V-Q-A-N-L-Y-P-C-V-V-Y-V-V-Q-G-G-A-I-P-Y-S-C-C-N-G-I-R-M-L-S-K-Q-A-T-S-A-S-D-K-Q-G-V-C-R-C-I-K-S-V-V-G-R-V-S-Y-S-S-I-Y-L-K-K-A-A-A-L-P-G-K-C-G-V-K-L-P-Y-K-I-D-P-S-T-N-C-N-S-I-K"} +{"text": "### FUNCTION Competitive inhibitor of the HD-ZIPIII transcription factors in shoot apical meristem development Acts by forming non-functional heterodimers Part of a negative feedback loop Essential for proper functioning of stem cells in the SAM ### SEQUENCE -M-C-L-T-T-S-E-P-P-F-P-D-T-D-T-P-T-M-R-S-A-S-Y-H-I-K-H-K-S-K-T-Q-T-H-L-R-I-L-N-L-T-R-R-R-R-L-L-K-E-Q-K-E-M-E-M-R-N-L-K-L-F-V-E-N-Q-S-I-I-R-E-N-E-A-L-K-K-K-A-L-L-L-H-H-E-N-N-A-L-F-A-L-L-H-P-K-Y-S-P-V-S-T-S-L-L-Q"} +{"text": "### FUNCTION Might have a systemic role in water and solute homeostasis ### SEQUENCE -M-S-K-S-I-V-F-F-S-T-V-L-V-F-L-F-S-F-S-Y-A-T-P-G-I-A-T-F-Y-T-S-Y-T-P-C-Y-R-G-T-Q-E-G-V-M-I-A-A-A-S-D-T-L-W-D-N-G-R-V-C-G-K-M-F-T-V-K-C-S-G-P-R-N-A-V-P-H-P-C-T-G-K-S-V-K-V-K-I-V-D-H-C-P-S-G-C-A-S-T-L-D-L-S-R-E-A-F-A-Q-I-A-N-P-V-A-G-I-I-N-I-D-Y-F-P"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-S-K-S-I-F-V-V-C-I-T-L-L-V-V-L-S-P-T-L-N-A-K-M-V-T-Y-P-N-G-D-R-H-C-V-M-A-Q-G-Q-V-I-S-A-C-L-Q-Q-A-N-G-L-P-H-A-D-C-C-Y-A-I-N-D-V-N-R-Y-V-E-T-I-Y-G-R-L-A-L-C-K-C-F-Q-E-I-L-K-D-S-R-F-T-K-L-I-G-M-P-E-K-C-A-I-P-N-A-V-P-F-D-P-K-T-D-C-D-R-F-V-E-H-I-W-L-K-M-F"} +{"text": "### FUNCTION Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events Histone deacetylases act via the formation of large multiprotein complexes ### SEQUENCE -M-A-F-S-M-L-F-T-G-H-A-E-C-G-G-Y-T-K-E-N-V-A-R-C-W-T-V-E-T-G-I-L-L-D-T-E-L-P-N-E-I-P-E-N-D-Y-I-K-Y-F-A-P-D-F-S-L-K-I-P-G-G-H-I-E-N-L-N-T-K-S-Y-I-S-S-I-K-V-Q-I-L-E-N-L-R-Y-I-Q-H-A-P-S-V-Q-M-Q-E-V-P-P-D-F-Y-I-P-D-F-D-E-D-E-Q-N-P-D-V-R-V-D-Q-R-S-R-D-K-Q-I-Q-R-D-D-E-Y-F-D-G-D-N-D-N-D-A-S"} +{"text": "### FUNCTION Probable vacuolar iron transporter that may be involved in the regulation of iron distribution throughout the plant ### SEQUENCE -M-E-S-N-N-N-N-L-N-L-D-M-E-K-D-Q-E-T-T-F-D-Y-S-K-R-A-Q-W-L-R-A-A-V-L-G-A-N-D-G-L-V-S-T-A-S-L-M-M-G-I-G-A-V-K-Q-D-V-R-I-M-L-L-T-G-F-A-G-L-V-A-G-A-C-S-M-A-I-G-E-F-I-S-V-Y-S-Q-Y-D-I-E-V-A-Q-M-K-R-E-S-G-G-E-T-K-K-E-K-L-P-S-P-T-Q-A-A-I-A-S-A-L-A-F-T-L-G-A-I-V-P-L-L-A-A-A-F-V-K-E-Y-K-V-R-I-G-V-I-V-A-A-V-T-L-A-L-V-M-F-G-W-L-G-A-V-L-G-K-A-P-V-V-K-S-L-V-R-V-L-I-G-G-W-L-A-M-A-I-T-F-G-F-T-K-L-V-G-S-H-G-L"} +{"text": "### FUNCTION May function as negative regulator of plant defense ### SEQUENCE -M-E-A-T-I-F-E-K-R-R-S-S-L-S-S-I-A-V-H-K-Q-S-Y-S-I-T-K-S-K-P-K-I-R-I-I-H-I-F-A-P-E-I-I-K-T-D-V-A-N-F-R-E-L-V-Q-S-L-T-G-K-P-D-D-Q-R-T-S-K-A-K-P-R-R-D-M-H-R-L-H-R-Q-V-Q-D-M-I-N-T-E-K-L-R-E-P-E-H-C-D-Q-E-F-C-L-N-A-E-E-L-S-M-T-W-N-G-N-N-G-A-G-E-S-S-G-G-F-L-N-G-L-G-D-F-E-G-F-I-Q-E-L-G-E-F-P-Y-L-P-L-S-S-I-D-A-S-A-S-S-N-S-S-S-S-S-H-L-H-G-G-S-V-F-S-D-Q-F-A"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-D-T-T-G-R-I-P-L-W-I-I-G-T-V-A-G-I-L-V-I-G-L-V-G-I-F-F-Y-G-S-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-N-W-R-S-E-R-I-W-V-E-F-I-T-G-S-R-K-I-S-N-F-C-W-A-F-I-L-F-L-G-S-S-G-F-L-L-V-G-I-S-S-Y-L-G-K-N-F-I-S-L-F-P-P-Q-Q-I-L-F-F-P-Q-G-L-V-M-S-F-Y-G-I-A-G-L-F-I-S-A-Y-L-W-C-A-I-S-W-N-V-G-S-G-Y-D-R-F-D-R-K-E-G-I-V-C-I-F-R-W-G-F-P-G-K-N-R-R-I-F-F-R-Y-L-I-K-D-I-Q-S-I-R-I-E-L-K-E-G-I-Y-T-R-R-V-L-Y-L-E-I-R-G-Q-G-A-I-P-L-T-R-T-D-E-N-L-T-P-R-E-M-E-Q-K-A-A-E-L-A-Y-F-L-R-V-P-I-E-V-F"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-S-R-N-G-N-F-I-D-K-T-F-S-V-V-A-N-I-L-L-Q-I-I-P-T-T-S-G-E-K-E-A-F-T-Y-Y-R-D-G-M-S-A-Q-S-E-G-N-Y-A-E-A-L-Q-N-Y-Y-E-A-M-R-L-E-I-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-E-H-T-K-A-L-E-Y-Y-F-R-A-L-E-R-N-P-F-L-P-Q-A-F-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-R-Q-G-D-S-E-I-A-E-A-W-F-D-Q-A-A-E-Y-W-K-Q-A-L-T-L-T-P-G-N-Y-I-E-A-H-N-W-L-K-I-T-G-R-F-E"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -M-T-I-A-F-Q-L-A-V-F-A-L-I-A-T-S-S-I-L-L-I-S-V-P-V-V-F-A-S-P-D-G-W-S-S-N-K-N-I-V-F-S-G-T-S-L-W-L-G-L-V-F-L-V-G-I-L-N-S-L-I-S"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-A-R-S-T-S-K-D-A-Q-A-L-I-Q-S-L-R-S-A-Y-A-A-T-P-S-N-L-K-I-I-D-L-Y-V-V-F-A-V-F-T-A-L-I-Q-V-V-Y-M-A-I-V-G-S-F-P-F-N-A-F-L-S-G-L-L-S-C-I-G-T-A-V-L-A-V-C-L-R-I-Q-V-N-K-E-N-K-E-F-K-D-L-A-P-E-R-A-F-A-D-F-V-L-C-N-L-V-L-H-L-V-I-M-N-F-L-G"} +{"text": "### FUNCTION Binds specifically to cytosolic chaperonin ### SEQUENCE -M-Q-Q-G-D-G-T-E-A-Q-V-T-W-E-D-Q-Q-N-I-N-R-F-G-R-L-N-N-R-F-H-E-L-T-D-E-I-R-L-A-K-E-A-N-E-N-L-E-D-A-G-N-E-L-I-L-C-D-E-D-V-V-R-F-Q-I-G-E-V-F-A-H-M-P-M-D-D-V-E-A-R-L-E-Q-M-K-E-D-A-A-K-K-L-E-R-L-E-E-E-K-E-S-I-L-A-Q-M-A-E-L-K-K-I-L-Y-G-K-F-K-D-A-I-N-L-E-E-D"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-V-Y-Q-D-K-L-S-G-D-E-L-L-S-D-S-F-P-Y-R-E-L-E-N-G-V-L-W-E-V-D-G-H-W-V-V-Q-G-A-V-D-V-D-I-G-A-N-P-S-A-E-G-G-G-E-D-E-G-V-D-D-Q-A-V-K-V-V-D-I-V-D-T-F-R-L-Q-E-Q-P-A-F-D-K-K-Q-F-I-A-Y-I-K-R-Y-I-K-N-L-T-A-K-L-E-G-E-E-L-D-A-F-K-K-N-V-E-S-A-T-K-Y-L-L-S-K-L-K-D-L-Q-F-F-V-G-E-S-M-H-D-D-G-S-V-V-F-A-Y-Y-R-E-G-A-A-D-P-T-F-L-Y-F-A-H-G-L-K-E-V-K-C"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-V-Y-Q-D-L-V-S-G-D-E-L-L-S-D-S-F-P-Y-K-E-I-E-N-G-M-I-W-E-V-E-G-K-W-V-V-K-G-A-V-D-V-D-I-G-A-N-P-S-A-E-G-G-G-E-D-E-G-V-D-D-Q-A-V-K-V-V-D-I-V-D-T-F-R-L-Q-E-Q-P-S-M-D-K-K-V-F-L-S-C-I-K-K-Y-I-K-K-L-T-P-L-L-Q-G-E-Q-Q-E-A-F-K-N-K-I-E-G-A-V-K-Y-L-L-P-K-V-K-D-L-Q-F-F-V-G-E-S-M-A-D-D-S-A-M-V-F-A-Y-Y-K-E-G-A-T-D-P-T-F-L-Y-I-A-P-G-L-K-E-V-K-C"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-A-S-S-A-V-I-K-L-A-L-V-V-A-L-C-M-A-V-S-V-A-H-A-I-T-C-S-Q-V-S-A-N-L-A-P-C-I-N-Y-V-R-S-G-G-A-V-P-P-A-C-C-N-G-I-K-T-I-N-G-L-A-K-T-T-P-D-R-Q-A-A-C-N-C-L-K-N-L-A-G-S-V-S-G-V-N-P-G-N-A-E-S-L-P-G-K-C-G-V-N-V-P-Y-K-I-S-T-S-T-N-C-A-T-V-K"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-A-S-S-A-V-T-K-L-A-L-V-V-A-L-C-M-A-V-S-V-A-H-A-I-T-C-G-Q-V-T-S-S-L-A-P-C-I-G-Y-V-R-S-G-G-A-V-P-P-A-C-C-N-G-I-R-T-I-N-G-L-A-R-T-T-A-D-R-Q-T-A-C-N-C-L-K-N-L-A-G-S-I-S-G-V-N-P-N-N-A-A-G-L-P-G-K-C-G-V-N-V-P-Y-K-I-S-T-S-T-N-C-A-T-V-K"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-A-C-S-A-M-T-K-L-A-L-V-V-A-L-C-M-V-V-S-V-P-I-A-Q-A-L-T-C-G-Q-V-S-S-N-L-A-P-C-I-A-Y-V-R-G-G-G-A-V-P-P-A-C-C-N-G-I-R-N-I-N-N-L-A-K-T-T-A-D-R-Q-T-A-C-N-C-L-K-Q-L-S-A-S-V-P-G-V-N-A-N-N-A-A-A-L-P-G-K-C-G-V-N-V-P-Y-K-I-S-P-S-T-N-C-A-T-V-K"} +{"text": "### FUNCTION May not function as an oxygen storage or transport protein, but might act as an oxygen sensor ### SEQUENCE -M-A-S-A-V-V-N-Q-S-E-A-A-A-V-R-A-P-S-K-P-V-K-T-Y-S-K-E-N-E-Q-L-V-K-Q-S-W-E-I-L-K-K-D-A-Q-R-N-G-I-N-F-F-R-K-V-F-E-I-A-P-G-A-K-A-M-Y-S-F-L-R-D-S-T-I-P-F-E-E-N-P-K-V-K-N-H-A-R-Y-V-F-M-M-T-G-D-A-A-V-Q-L-G-E-K-G-A-Y-Q-V-L-E-S-K-L-Q-K-L-A-A-T-H-V-N-A-G-V-T-D-D-Q-F-E-I-V-K-E-A-I-L-Y-A-I-E-M-G-V-P-D-L-W-S-P-E-L-K-S-A-W-G-D-A-Y-D-M-L-A-E-Q-V-K-A-E-M-H-A-Q-R-S-A-A-T-S"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-D-H-L-M-C-D-I-D-G-H-R-L-T-A-A-A-I-I-G-H-D-G-S-V-W-A-Q-S-S-G-F-P-Q-F-K-S-D-E-V-A-A-V-M-K-D-F-D-E-P-G-S-L-A-P-T-G-L-H-L-G-G-T-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-S-G-G-I-T-V-K-K-T-G-Q-A-L-I-I-G-I-Y-D-E-P-L-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-L-E-Q-G-M"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-D-H-L-M-C-D-I-D-G-H-R-L-T-A-A-A-I-I-G-H-D-G-S-V-W-A-Q-S-S-S-F-P-Q-F-K-S-D-E-V-A-A-I-M-K-D-F-D-E-P-G-S-L-A-P-T-G-L-H-L-G-S-T-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-S-G-G-I-T-V-K-K-T-S-Q-A-L-I-I-G-I-Y-D-E-P-L-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-L-E-Q-G-M"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-E-H-L-M-C-D-I-D-G-H-H-L-T-A-A-A-I-I-G-H-D-G-S-V-W-A-Q-S-S-S-F-P-Q-F-K-P-E-E-V-A-A-I-M-K-D-F-D-E-P-G-S-L-A-P-T-G-L-H-L-G-G-T-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-S-G-G-I-T-V-K-K-T-G-Q-A-L-I-I-G-I-Y-D-E-P-L-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-L-E-Q-G-M"} +{"text": "### FUNCTION May be involved in heavy metals transport ### SEQUENCE -M-G-R-V-T-T-P-S-E-E-D-S-N-N-G-L-P-V-Q-Q-P-G-T-P-N-Q-R-T-R-V-P-V-S-Q-F-A-P-P-N-Y-Q-Q-A-N-V-N-L-S-V-G-R-P-W-S-T-G-L-F-D-C-Q-A-D-Q-A-N-A-V-L-T-T-I-V-P-C-V-T-F-G-Q-I-A-E-V-M-D-E-G-E-M-T-C-P-L-G-T-F-M-Y-L-L-M-M-P-A-L-C-S-H-W-V-M-G-S-K-Y-R-E-K-M-R-R-K-F-N-L-V-E-A-P-Y-S-D-C-A-S-H-V-L-C-P-C-C-S-L-C-Q-E-Y-R-E-L-K-I-R-N-L-D-P-S-L-G-W-N-G-I-L-A-Q-G-Q-G-Q-Y-E-R-E-A-P-S-F-A-P-T-N-Q-Y-M-S-K"} +{"text": "### FUNCTION Putative gamma-glutamylcyclotransferase ### SEQUENCE -M-G-H-E-T-M-T-P-A-T-T-T-L-V-F-T-Y-G-T-L-K-R-G-F-S-N-H-V-L-M-Q-D-L-I-R-S-G-D-A-S-F-K-G-V-Y-Q-T-L-D-K-Y-P-L-V-C-G-P-Y-R-V-P-F-L-L-N-K-P-G-S-G-Y-H-V-N-G-E-L-Y-A-V-S-P-R-G-L-S-R-L-D-E-L-E-G-I-S-R-G-H-Y-I-R-Q-P-I-R-L-A-A-A-E-E-E-E-E-E-E-G-D-L-E-T-E-A-P-S-S-C-V-V-E-A-Y-Y-A-H-K-S-Y-E-E-E-L-W-R-R-N-R-G-R-S-F-G-A-Y-T-E-N-E-A-R-G-Y-V-K-R-N-D-R-P-Q-H-L-S-F-L-D-H-I-R-I-F-V-S-S-P-C-D"} +{"text": "### FUNCTION The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins ### SEQUENCE -M-E-S-C-P-S-V-K-N-I-L-L-L-D-S-E-G-K-R-V-A-V-K-Y-Y-T-D-D-W-P-T-L-S-A-K-L-A-F-E-K-S-V-F-V-K-T-Q-K-A-T-A-G-A-E-A-E-I-V-M-F-D-G-H-I-V-V-Y-K-F-I-Q-D-L-H-F-F-V-T-G-G-E-E-E-N-E-L-I-L-A-S-V-L-Q-G-F-T-D-A-V-D-I-I-L-R-N-N-V-D-K-R-T-A-L-E-N-L-D-L-I-L-L-C-L-D-E-I-V-D-G-G-I-V-L-E-T-E-G-S-V-I-A-E-K-V-S-A-H-G-I-E-G-A-T-S-L-A-E-Q-T-I-V-Q-A-L-T-T-A-R-E-H-L-T-K-S-L-L-M"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-E-S-K-S-S-S-S-S-L-P-L-F-A-L-F-N-F-F-L-I-S-F-C-R-W-V-S-S-T-R-I-F-L-S-R-F-V-P-L-L-Q-H-H-Q-R-V-F-D-K-K-N-N-K-D-Q-Q-E-T-L-T-K-Q-E-D-D-D-D-D-D-D-D-D-D-D-D-D-D-D-D-I-D-I-S-R-E-E-A-E-M-V-M-R-S-L-G-L-F-Y-N-D-D-Q-L-Q-E-Q-Y-S-A-K-E-V-S-S-L-F-E-E-K-E-A-S-L-E-E-V-K-Q-A-F-D-V-F-D-E-N-K-D-G-F-I-D-A-I-E-L-Q-R-V-L-T-I-L-G-F-K-Q-G-S-Y-L-D-N-C-L-V-M-I-R-S-L-D-G-N-K-D-G-K-I-D-F-N-E-F-V-K-F-M-E-T-S-F-Y"} +{"text": "### FUNCTION Putative gamma-glutamylcyclotransferase ### SEQUENCE -M-T-S-S-D-P-Q-S-H-N-V-F-V-Y-G-S-I-L-E-P-A-V-A-A-V-I-L-D-R-T-A-D-T-V-P-A-V-L-H-G-Y-H-R-Y-K-L-K-G-L-P-Y-P-C-I-V-S-S-D-S-G-K-V-N-G-K-V-I-T-G-V-S-D-A-E-L-N-N-F-D-V-I-E-G-N-D-Y-E-R-V-T-V-E-V-V-R-M-D-N-S-E-K-V-K-V-E-T-Y-V-W-V-N-K-D-D-P-R-M-Y-G-E-W-D-F-E-E-W-R-V-V-H-A-E-K-F-V-E-T-F-R-K-M-L-E-W-N-K-N-P-N-G-K-S-M-E-E-A-V-G-S-L-L-S-S-G-D"} +{"text": "### FUNCTION Single-stranded DNA-binding protein required for the elongation during viral DNA replication by strand displacement Displaced viral DNA strands are transiently coated with the ssDNA-binding protein and therefore protected againt nucleases The latter is then probably removed by the replisome that performs lagging strand synthesis or during the events that lead up to the recombination process Has helix-destabilizing activity since it removes secondary structure from the ssDNA in replicative intermediates ### SEQUENCE -M-T-N-E-I-K-A-T-F-D-V-T-T-L-E-G-R-M-K-I-L-N-A-K-N-A-G-G-A-S-L-K-T-C-E-D-G-A-I-I-E-A-V-G-I-A-Q-Y-Q-Q-E-S-D-T-Y-G-D-M-K-E-E-T-V-T-A-I-F-T-A-D-G-N-V-I-S-A-I-S-K-T-V-A-E-A-A-S-E-I-I-D-L-V-K-E-F-N-L-D-S-F-K-V-K-V-S-K-Q-K-S-S-K-G-N-E-F-F-S-L-L-L-V-G"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-D-G-I-K-Y-A-V-F-T-D-K-G-V-R-L-L-G-K-N-Q-Y-T-S-N-V-E-S-G-S-T-R-T-E-I-K-H-W-V-E-L-F-F-G-V-K-V-Q-A-M-N-S-H-R-L-P-G-K-G-R-R-M-G-P-I-M-G-H-T-M-H-Y-R-R-M-I-I-T-L-Q-P-G-Y-S-I-P-P-L-R-K-K-R-T"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-P-Q-L-N-P-S-P-W-F-F-I-M-L-T-T-W-L-T-F-S-L-I-I-Q-P-K-L-L-S-F-T-P-T-N-P-P-S-N-K-I-S-T-T-T-K-T-T-P-W-T-W-P-W-T"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-P-Q-L-N-P-H-P-W-F-F-I-M-L-A-S-W-L-T-F-S-L-I-I-Q-P-K-L-L-T-F-V-T-M-N-P-P-S-N-K-P-P-I-A-P-S-T-T-P-W-T-W-P-W-T"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-I-K-Q-L-I-R-N-T-R-Q-P-I-R-N-V-T-K-S-P-A-L-R-G-C-P-Q-R-R-G-T-C-T-R-V-Y-T-I-N-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-I-T-A-Y-I-P-G-I-G-H-N-S-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-A-V-G-V-K-D-R-Q-Q-G-R-S-K-Y-G-V-K-R-P-K"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-P-Q-L-E-F-T-W-W-I-I-N-F-F-I-V-W-T-A-D-F-T-L-L-I-V-L-S-I-P-N-L-S-T-P-T-T-L-S-K-Q-L-D-I-N-K-S-H-V-T-W-Q-W-S"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-I-V-I-V-Q-L-G-S-L-A-L-I-T-L-A-G-P-I-I-I-V-L-L-F-L-K-Q-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-F-S-I-N-F-L-G-L-L-P-E-A-Y-A-P-F-D-P-I-V-D-V-L-P-I-I-P-L-L-F-L-L-L-A-F-V-W-Q-S-S-V-R-F-R"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-A-E-L-I-V-Q-L-G-S-L-A-L-I-T-V-A-G-P-A-I-I-V-L-L-F-L-K-Q-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-F-Q-I-S-L-D-M-I-S-N-K-I-N-L-L-G-L-L-P-E-A-Y-A-P-F-D-H-I-V-D-V-L-P-I-I-P-I-L-F-F-L-L-A-F-V-W-Q-A-S-V-K-F-R"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-I-E-L-I-V-Q-L-T-S-L-A-L-I-T-L-A-G-P-L-I-V-A-L-L-F-L-K-Q-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-F-P-S-T-N-Q-E-V-L-A-L-L-P-E-A-Y-A-P-F-D-P-I-V-D-V-L-P-I-I-P-L-L-F-L-L-L-A-F-V-W-Q-A-S-V-K-F-R"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-I-E-L-I-V-Q-L-T-S-L-I-L-I-S-I-A-G-P-I-I-I-A-L-L-F-V-K-Q-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-N-L-N-F-T-N-I-T-V-M-G-I-L-P-E-A-Y-A-P-F-D-P-I-V-D-I-L-P-I-I-P-I-L-F-F-L-L-A-F-V-W-Q-A-A-V-K-F-R"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-I-E-L-I-V-Q-L-G-S-L-T-L-I-T-I-A-G-P-L-I-V-A-L-L-F-L-R-Q-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-L-E-H-V-T-I-T-L-L-N-N-T-S-F-A-L-L-P-E-A-Y-A-P-F-D-P-L-I-D-V-L-P-I-I-P-L-L-F-L-L-L-A-F-V-W-Q-A-S-V-K-F-R"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-T-E-L-I-V-Q-L-G-S-L-T-L-I-T-L-A-G-P-L-V-V-V-L-L-F-L-K-Q-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-F-E-N-F-A-I-I-T-L-K-E-N-V-F-A-L-L-P-E-A-Y-A-P-F-D-P-I-V-D-D-L-P-I-I-P-V-L-F-L-L-L-A-F-V-W-Q-S-A-V-K-F-R"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-I-E-L-I-T-Q-L-A-S-L-I-L-I-V-A-S-G-P-I-V-I-G-L-L-S-L-K-Q-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-F-L-F-N-L-E-Q-S-I-G-L-L-P-E-A-Y-L-P-F-D-P-L-V-D-V-L-P-I-I-P-L-L-F-L-L-L-A-F-V-W-Q-A-A-V-K-F-R"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-L-E-L-V-V-Q-L-G-S-L-L-L-I-T-V-A-G-P-L-I-V-F-F-L-F-I-R-Q-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-F-Y-T-N-V-E-T-L-L-N-T-N-C-F-A-L-L-P-E-A-Y-A-P-F-D-P-L-V-D-V-L-P-I-I-P-L-L-F-L-L-L-A-F-V-W-Q-A-A-V-K-F-R"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-E-L-L-I-Q-L-T-S-L-L-L-I-V-I-A-G-P-L-V-I-A-L-L-F-L-K-Q-G-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-I-S-S-I-H-L-R-K-L-L-G-L-L-P-E-A-Y-L-P-F-D-P-I-I-D-V-L-P-I-I-P-V-L-F-L-L-L-A-F-V-W-Q-A-A-V-K-F-R"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-L-E-K-S-K-Q-K-N-S-F-D-K-N-K-F-I-I-N-N-K-I-S-F-P-I-V-R-I-I-D-E-N-N-Y-Q-L-G-I-Y-K-I-E-D-A-L-K-L-A-E-E-K-N-L-D-L-V-L-I-N-D-K-T-E-P-P-V-V-R-I-I-D-Y-G-K-F-K-F-A-Q-E-K-K-S-R-E-A-K-K-K-Q-H-Q-V-T-V-K-E-I-K-M-R-Y-K-I-E-D-H-D-Y-Q-V-R-I-N-Q-A-I-K-F-L-K-L-G-N-K-V-K-I-S-L-T-F-K-G-R-E-I-Q-Y-I-D-L-A-E-K-L-I-E-K-I-I-H-S-L-S-S-L-A-E-H-E-K-V-F-D-K-E-G-K-N-I-Y-I-M-L-L-P-K-K-T"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-G-T-A-E-E-K-T-A-K-S-D-P-I-Y-R-N-R-L-V-N-M-L-V-N-R-I-L-K-H-G-K-K-S-L-A-Y-Q-I-I-Y-R-A-V-K-K-I-Q-Q-K-T-E-T-N-P-L-S-V-L-R-Q-A-I-R-G-V-T-P-N-I-A-V-K-A-R-R-V-G-G-S-T-H-Q-V-P-I-E-I-G-S-T-Q-G-K-A-L-A-I-R-W-L-L-G-A-S-R-K-R-P-G-R-N-M-A-F-K-L-S-S-E-L-V-D-A-A-R-G-S-G-D-A-I-R-K-K-E-E-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-N-K-K-M-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-S-T-A-E-K-E-T-A-K-S-D-P-I-Y-R-N-R-L-V-N-M-L-V-N-R-I-L-R-H-G-K-K-S-L-A-Y-R-I-L-Y-R-A-M-K-N-I-Q-Q-K-T-E-K-N-P-L-S-V-L-R-Q-A-I-R-G-V-T-P-N-V-T-V-K-A-R-R-V-G-G-S-T-Y-Q-V-P-I-E-I-R-S-T-Q-G-K-A-L-A-I-R-W-S-L-G-A-S-R-K-R-P-P-G-R-N-M-A-F-K-L-S-Y-E-L-M-D-A-A-R-E-N-G-N-A-I-R-K-K-E-E-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-R-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-E-Q-L-R-D-P-F-E-E-H-E-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-D-R-G-S-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-K-R-S-L-K-N-N-P-F-V-A-N-P-L-L-R-K-M-E-K-L-N-R-R-E-D-K-I-L-I-R-T-W-S-R-A-S-T-I-I-L-T-M-I-G-H-T-I-A-I-H-N-G-K-E-H-L-P-I-Y-I-T-D-Y-M-V-G-H-K-L-G-E-F-A-P-T-I-N-F-H-E-H-A-K-N-D-N-K-S-R-R-S-K-M-R-I-D-Y"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-K-K-K-K-T-Y-G-E-V-Y-A-L-G-Q-Y-I-S-M-S-A-P-K-A-R-R-V-I-D-Q-I-R-G-R-S-Y-E-E-T-L-M-L-L-A-L-M-P-Y-R-A-C-D-P-I-L-K-L-V-N-S-A-A-A-N-A-R-H-N-M-S-F-N-E-A-T-L-V-I-S-K-A-E-V-N-E-G-T-T-V-K-K-L-K-P-R-A-R-G-R-S-Y-P-I-R-R-P-T-C-H-I-R-I-V-L-Q-D-T-S-F-D-E-F-E-E-D-F-F-S-L-K-K-D-A-W-E-K-K"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-P-Q-T-R-L-N-V-A-D-N-S-G-A-R-E-L-M-C-I-R-I-I-G-A-S-N-R-R-Y-A-H-I-G-D-I-I-V-A-V-I-K-E-A-L-P-S-T-S-L-E-R-S-E-V-V-R-A-V-I-V-R-T-C-K-E-L-K-C-D-D-G-I-I-I-R-Y-D-D-N-A-A-V-V-I-D-Q-E-G-N-P-K-G-T-R-V-F-G-A-I-A-H-E-L-R-E-L-S-F-T-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-R-D-T-I-A-D-I-I-T-S-I-R-N-V-D-M-N-R-K-G-T-V-R-I-E-S-T-N-M-A-E-K-I-V-K-I-L-L-R-E-G-F-I-E-N-V-R-K-H-Q-E-N-K-K-S-F-L-V-L-T-L-R-H-R-R-N-R-K-G-P-S-P-S-R-T-F-L-N-L-N-L-K-R-I-S-R-P-G-L-R-V-Y-S-N-Y-Q-K-I-P-R-I-L-G-G-M-G-I-V-I-L-S-T-S-R-G-I-M-T-D-R-E-A-R-L-E-G-I-G-G-E-I-L-C-Y-I-W"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-G-V-T-K-K-P-D-L-N-D-P-V-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-V-V-I-L-G-T-I-A-C-N-V-G-L-A-I-L-E-P-S-M-L-G-E-P-A-D-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-F-P-V-F-Q-I-L-R-T-V-P-N-K-L-L-G-V-L-L-M-V-S-V-P-S-G-L-L-T-V-P-F-L-E-N-V-N-K-F-Q-N-P-F-R-R-P-V-A-T-T-V-F-L-I-G-T-V-V-A-L-W-L-G-I-G-A-T-L-P-I-D-K-S-L-T-L-G-L-F"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-I-R-R-G-Y-I-A-R-R-R-R-T-K-T-R-F-F-A-S-S-W-R-G-A-R-G-N-L-T-R-A-I-I-Q-Q-R-I-R-A-W-F-S-S-H-R-D-R-T-R-Q-K-R-D-F-R-R-L-W-I-T-R-I-N-A-A-I-R-E-N-G-R-S-S-I-Y-S-K-L-I-H-N-L-Y-K-R-Q-L-F-L-N-R-K-M-L-A-Q-L-A-I-L-N-R-N-C-L-Y-M-I-S-N-Q-I-L-K-E-V-D-W-Q-E-S-A-T-I-L-E-I"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-R-D-L-K-T-Y-L-S-V-A-P-V-L-S-A-L-W-F-G-A-L-A-G-L-L-I-E-I-N-R-F-F-P-D-A-L-T-F-P-F-F-S"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex ### SEQUENCE -M-L-T-I-T-S-F-F-G-F-L-L-A-A-L-T-I-T-S-V-L-F-I-G-L-T-K-I-R-L-I"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-D-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-D-T-T-G-R-I-P-L-W-I-I-G-T-V-A-G-I-L-V-I-G-L-I-G-I-F-F-Y-G-A-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-I-W-R-S-E-H-I-W-I-E-L-I-V-G-S-R-K-I-S-N-F-C-W-A-F-L-L-F-L-G-S-L-G-F-V-L-V-G-T-S-S-Y-L-G-K-N-L-I-S-L-V-S-S-Q-Q-I-H-F-F-P-Q-G-L-V-M-S-F-Y-G-I-A-G-L-F-I-S-S-Y-L-W-C-T-I-S-W-N-V-G-S-G-Y-D-R-F-D-R-K-E-G-I-V-C-I-F-R-W-G-F-P-G-K-N-R-R-I-F-L-R-F-R-M-K-D-I-Q-S-I-R-I-E-V-K-E-G-I-Y-A-R-R-V-L-Y-M-E-I-K-G-Q-G-A-I-P-L-T-R-S-D-D-N-L-T-L-R-E-I-E-Q-K-A-A-E-L-A-Y-F-L-R-V-P-I-E-V-F"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-T-D-F-P-S-I-F-V-P-L-V-G-L-V-F-P-A-I-A-M-A-S-L-S-L-H-V-E-N-N-K-I-V"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-N-I-F-S-L-I-C-L-N-S-D-L-Y-S-S-R-F-F-L-A-K-L-P-E-A-Y-A-F-L-N-P-I-V-D-V-M-P-V-I-P-L-F-F-L-L-L-A-F-V-W-Q-A-A-V-S-F-R"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-N-V-T-D-S-F-V-S-L-V-H-W-P-S-A-G-S-F-G-F-N-T-D-I-L-A-T-N-P-I-N-L-S-V-V-L-G-V-L-I-F-F-G-K-G-V-L-S-D-L-L-D-N-R-K-Q-R-I-L-N-T-I-R-N-S-E-E-L-R-E-G-A-I-E-Q-L-E-K-A-R-A-R-L-Q-D-V-Q-I-E-A-E-G-Y-R-A-Y-G-Y-F-G-I-D-E-Q-R-H-E-S-I-N-S-T-Y-K-T-L-E-Q-L-E-N-N-K-N-E-S-I-H-F-E-Q-Q-R-A-I-N-Q-V-R-Q-Q-I-F-Q-Q-A-L-Q-G-A-L-G-T-L-N-S-C-L-N-N-E-L-H-L-R-T-I-S-A-N-I-G-L-F-G-S-M-K-E-L-T-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-V-P-T-A-F-L-L-I-I-Y-V-K-T-V-S-Q-S-D"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -M-T-I-A-F-Q-L-A-V-F-A-L-I-A-T-S-S-L-L-L-I-S-V-P-V-V-F-A-S-P-E-G-W-S-S-N-K-N-V-V-F-S-G-T-S-L-W-I-G-L-V-F-L-V-G-I-L-N-S-L-I-S"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-R-K-G-L-I-Q-R-E-K-K-R-E-K-L-E-Q-K-Y-R-L-I-R-R-S-S-K-K-E-I-S-T-A-P-S-L-S-E-K-W-K-I-H-G-K-L-Q-S-S-P-R-N-S-A-P-T-R-L-H-R-R-C-F-S-T-G-R-P-R-A-N-Y-R-D-F-R-L-S-G-H-I-L-R-E-M-V-H-A-C-L-L-P-G-A-T-R-S-S-W"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-R-I-N-G-N-F-I-D-K-T-F-S-I-V-A-N-I-L-L-R-I-I-P-T-T-S-G-E-K-E-A-F-T-Y-Y-R-D-G-M-S-A-Q-S-E-G-N-Y-A-E-A-L-Q-N-Y-Y-E-A-M-R-L-E-I-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-E-H-T-K-A-L-E-Y-Y-F-R-A-L-E-R-N-P-F-L-P-Q-A-F-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-R-Q-G-D-S-E-I-A-E-A-W-F-D-Q-A-A-E-Y-W-K-Q-A-I-A-L-T-P-G-N-Y-I-E-A-Q-N-W-L-K-I-T-R-R-F-E"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-T-L-N-L-C-V-L-T-P-N-R-I-V-W-D-S-E-V-K-E-I-I-L-S-T-N-S-G-Q-I-G-V-L-P-N-H-A-P-I-A-T-A-V-D-I-G-I-L-R-I-R-Q-N-G-Q-W-L-T-M-A-L-M-G-G-F-A-R-I-G-N-N-E-I-T-I-L-V-N-D-A-E-K-G-S-D-I-D-P-Q-E-A-Q-E-T-L-G-L-A-E-A-N-F-R-K-A-E-G-K-R-Q-T-I-E-A-N-L-A-L-R-R-A-R-T-R-V-E-A-I-N-V-I-S"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-V-V-R-L-P-Y-V-K-G-S-I-L-C-S-A-L-A-K-G-C-G-H-N-Y-Y-G-E-P-A-W-P-N-D-I-L-Y-I-F-P-V-V-I-L-G-T-I-S-F-S-L-G-L-G-V-I-E-N-Q-A-I-G-E-P-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-F-P-T-F-N-L-L-R-I-L-P-D-K-L-V-G-V-L-S-L-A-S-V-P-V-I-L-V-L-T-A-F-I-E-N-I-N-R-Y-Q-N-P-F-R-R-P-V-A-S-L-V-Y-L-T-S-T-C-Y-A-L-W-L-G-Y-G-S-V-L-G-I-S-E-A-L-P-F-V"} +{"text": "### FUNCTION May be involved in RNA polymerase activity ### SEQUENCE -M-R-N-K-I-P-Y-D-S-K-K-I-L-Y-D-S-E-L-L-L-N-S-A-S-N-R-Y-I-L-T-M-K-V-A-N-R-A-N-L-R-R-Y-E-E-F-E-T-M-N-H-S-S-I-K-P-I-A-R-T-I-I-E-M-V-D-D-K-N-F-L-V-V-K-K-K"} +{"text": "### FUNCTION Probably a ribosomal protein or a ribosome-associated protein ### SEQUENCE -M-N-I-F-I-K-Q-N-S-S-T-V-K-R-R-Y-P-L-Q-K-F-V-L-K-F-L-W-L-E-K-N-L-A-V-T-V-D-Q-V-T-N-R-G-N-S-P-I-T-E-Y-F-F-W-P-R-K-D-A-W-E-E-L-K-D-A-L-A-N-K-P-W-I-S-Y-D-E-S-I-A-L-L-N-Q-T-T-D-V-I-N-Y-W-Q-E-D-E-K-K-P-S-L-S-E-A-Q-A-K-F-P-N-C-I-F-T-D-K-F-A-N-C-L-Y-E-N"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-V-E-S-L-L-S-G-I-V-L-G-M-I-P-I-T-L-A-G-L-F-V-T-A-Y-L-Q-Y-R-R-G-D-Q-L-K-I"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex ### SEQUENCE -M-F-T-V-V-S-Y-L-G-I-L-A-A-F-A-L-V-T-I-G-I-F-L-V-L-R-T-I-Q-L-I"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-I-N-F-S-T-N-S-D-L-I-L-R-E-S-V-V-G-S-R-R-I-S-N-Y-W-W-A-S-V-V-L-L-G-A-S-G-F-L-I-V-G-I-S-S-Y-L-Q-Y-D-L-V-P-F-L-S-A-K-N-I-V-F-V-P-Q-G-L-V-M-C-F-Y-G-S-A-G-I-L-L-S-I-Y-L-W-L-T-I-F-W-N-V-G-E-G-Y-N-E-F-D-K-V-N-G-L-V-R-I-F-R-W-G-Y-P-G-K-D-R-R-I-N-I-V-Y-D-I-K-D-I-Q-A-I-R-V-E-I-K-E-G-I-N-P-R-R-V-I-Y-L-K-I-K-G-T-R-D-M-P-L-T-R-I-G-Q-P-L-T-L-A-E-I-E-E-Q-A-A-R-L-A-R-F-L-Q-V-N-I-E-G-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-S-T-P-K-K-R-I-I-D-S-D-P-I-Y-R-S-R-L-V-T-M-L-I-S-H-I-L-K-E-G-K-K-S-L-A-Q-K-I-F-Y-Q-A-M-K-N-I-E-E-K-T-E-K-D-P-L-K-V-L-Q-Q-A-V-L-N-A-T-P-L-V-E-V-K-A-R-R-L-G-G-S-T-Y-Q-V-P-R-E-V-K-A-E-R-G-T-A-L-A-L-R-W-L-L-S-S-A-R-Q-R-P-G-R-N-M-V-A-K-L-T-N-E-I-V-D-A-A-N-E-T-G-N-A-I-R-K-R-E-E-T-H-R-M-A-E-A-N-K-A-F-S-H-Y-R-F"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-I-Q-Q-L-I-R-S-E-R-K-R-V-Y-N-K-T-K-S-P-A-L-K-A-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-I-R-G-I-L-D-T-A-G-V-K-D-R-A-Q-S-R-S-K-Y-G-V-K-R-S"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-Q-D-F-Q-K-Y-L-S-T-A-P-V-L-A-T-I-W-F-I-I-L-A-G-L-L-I-E-I-N-R-F-F-P-D-A-L-L-V-P-M-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-V-K-R-G-N-V-A-R-K-H-R-N-K-I-L-N-L-A-K-G-F-R-G-A-H-S-V-L-F-R-T-A-N-Q-Q-I-I-K-S-L-R-Y-A-Y-R-D-R-A-R-K-K-R-D-F-R-K-L-W-I-A-R-I-N-A-A-S-R-Q-N-N-I-S-Y-S-Q-L-I-N-Q-L-K-T-S-N-I-L-L-N-R-K-I-L-A-Q-I-A-L-L-D-G-P-V-F-S-Q-I-V-M-E-S-N-S"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -M-L-A-A-F-Q-L-T-V-L-A-L-I-A-T-S-F-L-M-V-I-G-V-P-V-I-F-A-S-P-E-G-W-V-K-S-K-N-F-V-F-S-G-A-L-L-W-I-S-L-V-F-A-V-G-I-L-N-S-F-V-V"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-E-P-N-P-N-K-Q-E-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-I-L-F-S-S-Y-I-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-N-T-G-T-T-G-R-I-P-L-W-L-V-G-T-V-V-G-L-L-A-I-G-L-L-A-L-F-F-Y-G-S-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-I-A-S-Y-L-P-S-I-L-V-P-L-V-G-L-V-F-P-A-I-A-M-A-S-L-F-L-Y-I-E-Q-E-E-I-S"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-T-N-I-L-A-L-M-A-T-A-L-F-I-I-I-P-T-A-F-L-I-I-L-Y-A-Q-T-N-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-K-K-S-M-I-E-R-E-K-K-R-Q-K-L-V-N-K-Y-A-V-K-R-K-E-L-K-E-Q-I-K-T-S-V-S-F-E-E-R-F-K-L-Q-L-E-L-Q-K-L-P-R-N-S-S-P-T-R-L-H-N-R-C-S-V-T-G-R-P-K-G-Y-Y-R-D-F-G-L-S-R-H-V-L-R-E-M-A-H-E-C-L-L-P-G-V-T-K-S-S-W"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-N-I-G-F-D-M-I-L-A-K-L-P-E-A-Y-A-M-F-D-P-L-V-D-V-L-P-V-I-P-L-L-F-L-L-L-A-F-V-W-Q-A-S-V-S-F-R"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-I-F-V-Y-T-V-V-I-F-F-V-S-L-F-I-F-G-F-L-S-S-D-T-G-R-N-P-K-R-K-D-I-E"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-L-E-V-V-V-Q-L-G-S-L-S-L-I-V-L-A-G-P-I-I-V-L-L-L-A-S-Q-K-G-N-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-I-I-S-L-G-W-V-F-L-M-V-F-F-S-F-S-L-S-L-V-V-W-A-R-N-G-L"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-T-D-I-L-T-N-I-F-T-I-L-S-R-M-S-L-A-E-G-F-G-F-N-T-D-I-F-E-T-N-I-L-N-L-A-V-V-L-G-I-L-L-T-S-G-R-E-F-F-V-S-L-L-Q-N-R-Q-Q-N-I-L-Q-S-I-N-D-A-D-E-R-Y-K-E-A-A-E-K-L-Q-Q-A-Q-N-E-F-E-Q-A-K-L-E-A-D-Q-I-L-A-Q-S-K-K-T-A-S-E-I-E-V-G-L-M-N-L-I-K-E-D-T-K-K-L-L-D-M-K-Q-A-T-I-S-F-E-E-E-K-A-I-S-E-I-R-R-Q-V-I-R-L-A-L-Q-R-A-L-E-Q-S-K-S-R-L-N-R-R-L-Q-K-R-V-T-R-L-N-I-G-L-L-G-R-L-V-T-P-N-D-V"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-F-Q-V-R-I-I-A-P-N-G-I-I-W-D-S-E-A-E-E-I-I-L-S-T-N-T-G-K-I-G-V-L-T-N-H-T-S-L-L-T-G-L-D-I-G-T-I-R-I-R-A-L-N-N-Q-W-N-T-L-A-L-M-S-G-F-A-V-I-K-D-N-V-A-T-I-I-V-S-E-A-E-N-G-A-N-I-K-S-E-E-A-Q-T-Q-L-E-E-A-K-S-Y-F-N-T-A-K-G-T-K-N-E-V-E-A-N-L-A-V-K-R-A-E-T-R-L-K-A-S-Q-N-L"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-Q-K-N-D-N-F-I-D-K-T-F-T-V-V-A-D-I-I-L-K-V-L-P-T-T-V-R-E-K-A-A-F-S-Y-Y-R-D-G-M-S-A-Q-A-E-G-E-Y-A-E-A-L-Q-N-Y-Y-E-A-M-R-L-E-I-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-E-H-G-K-A-L-E-Y-Y-Y-Q-A-I-E-R-N-P-S-L-P-Q-A-L-N-N-I-A-V-I-Y-H-Y-R-G-E-Q-A-I-E-E-G-N-I-A-T-S-E-I-L-F-N-Q-A-A-S-Y-W-K-Q-A-I-R-L-A-P-N-S-Y-I-E-A-Q-N-W-L-K-I-T-G-R-I-E-D-N-I-N-L"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-D-I-V-K-Y-P-V-L-T-E-K-A-T-R-L-L-E-N-N-Q-Y-T-F-D-V-D-P-K-A-N-K-I-T-I-K-A-L-I-E-D-F-F-N-V-K-V-L-S-V-N-T-H-R-P-P-R-K-K-R-R-I-G-R-S-E-G-Y-R-P-N-Y-K-R-V-I-V-T-L-K-T-G-D-S-I-K-L-L-P-E-T"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-V-A-D-H-L-L-K-K-I-E-F-L-N-V-K-K-E-K-K-V-I-T-T-W-S-R-G-S-T-I-L-P-I-M-I-G-H-T-I-A-V-H-N-G-R-E-H-L-P-I-F-I-T-D-Q-M-V-G-H-K-L-G-E-F-S-P-T-R-T-F-R-G-H-T-K-S-D-K-K-S-R-R-P"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-N-M-T-R-D-A-D-L-K-V-K-A-V-A-R-G-V-F-M-S-P-Q-K-V-R-R-V-L-D-Q-I-R-G-R-S-Y-E-E-A-L-M-I-L-Q-F-M-P-Y-R-A-C-E-P-I-S-K-V-L-Y-S-A-A-A-N-A-K-N-N-L-G-L-T-K-A-S-L-S-I-S-E-A-K-V-D-K-G-P-I-L-K-R-F-R-P-R-A-Q-G-R-G-F-P-I-R-K-P-T-C-Q-I-S-I-T-V-Q-S-I-K"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-A-Q-S-Y-L-N-V-A-D-N-S-G-A-K-K-I-M-C-I-R-V-L-G-G-S-Q-R-K-Y-A-A-I-G-D-V-I-I-G-V-V-K-D-S-V-P-N-M-S-L-K-K-S-E-V-V-R-A-V-V-V-R-T-C-K-G-I-R-R-E-N-G-M-T-I-R-F-D-D-N-A-A-V-V-I-N-K-D-G-N-P-K-G-T-R-V-F-G-P-V-A-R-E-L-R-D-R-N-F-T-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION Binds 5S rRNA, forms part of the central protuberance of the 50S subunit ### SEQUENCE -M-V-Q-R-L-K-T-L-Y-L-E-S-A-V-L-K-L-Q-E-T-F-G-Y-K-N-P-H-Q-I-P-R-I-K-K-I-V-I-N-C-G-L-S-E-A-S-Q-N-S-K-S-L-E-S-A-M-K-E-L-S-I-I-A-G-Q-K-G-V-I-T-R-A-K-K-A-I-A-G-F-K-I-R-E-G-L-P-I-G-I-C-I-T-L-R-G-D-S-M-Y-A-F-L-D-R-L-I-N-L-A-L-P-R-I-R-D-F-Q-G-V-S-S-K-S-F-D-G-H-G-N-Y-N-L-G-L-K-E-Q-L-M-F-P-E-I-D-Y-D-Q-I-D-K-I-R-G-M-D-I-C-I-V-T-N-A-K-T-D-S-E-G-F-Y-L-L-E-V-L-G-M-P-F-K-E-K-F-A-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-N-D-T-I-A-D-M-I-T-R-I-R-N-A-N-L-I-T-Q-K-Q-V-A-V-I-A-S-N-T-N-K-G-I-A-Q-C-L-L-K-E-G-F-I-E-S-I-E-Y-N-T-N-S-S-N-N-P-E-L-I-L-S-L-K-Y-Q-G-K-K-R-K-P-Y-I-T-A-L-Q-R-V-S-K-S-G-L-R-V-Y-T-S-Y-K-D-I-P-K-V-L-G-G-I-G-I-A-I-L-S-T-S-Q-G-I-L-T-D-K-Q-A-R-M-Q-K-I-G-G-E-I-L-C-Y-I-W"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-E-R-Q-N-L-I-E-M-E-G-V-I-T-E-S-L-P-N-A-M-F-R-V-H-L-D-N-G-F-N-V-L-A-H-I-S-G-K-I-R-R-N-Y-I-R-I-L-P-G-D-R-V-K-I-E-L-T-P-Y-D-L-T-K-G-R-I-T-Y-R-L-R-K-R"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-S-L-Q-K-K-P-D-L-K-D-P-V-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-T-F-P-V-C-I-L-G-T-I-G-C-L-V-G-L-A-V-L-E-P-T-M-F-G-E-P-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-F-P-V-F-Q-I-L-R-V-I-P-N-K-L-L-G-V-V-L-M-A-G-V-P-A-G-L-L-T-V-P-F-I-E-S-I-N-K-F-Q-N-P-F-R-R-P-V-A-M-T-V-F-L-I-G-T-V-V-A-V-W-L-G-I-G-A-T-L-P-I-D-T-S-L-T-L-G-F-F"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-D-T-S-Q-G-K-R-T-V-V-G-N-F-L-K-P-L-N-S-E-Y-G-K-V-A-P-G-W-G-T-T-V-L-M-G-V-F-M-A-L-F-A-V-F-L-V-I-I-L-Q-I-Y-N-A-S-V-L-L-D-G-I-P-A-N-W-S-S-L-S-K-Y"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-I-F-S-I-F-F-S-C-L-L-I-G-L-T-G-Y-S-L-Y-T-S-F-G-N-A-S-S-E-L-R-D-P-F-E-E-H-E-D"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-G-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-R-I-I-K"} +{"text": "### FUNCTION Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals ### SEQUENCE -M-L-R-L-F-L-S-H-L-L-G-V-W-L-L-L-S-L-R-A-R-K-I-P-A-Q-E-E-V-L-K-A-C-G-R-E-F-V-R-L-Q-I-R-I-C-G-S-L-S-W-G-K-S-S-Q-Q-H-R-E-P-R-Q-A-P-A-A-L-P-E-I-V-S-S-S-I-T-S-G-A-E-A-L-N-G-M-L-E-Y-I-P-D-L-P-Q-E-L-K-A-T-L-S-E-R-E-P-S-F-R-E-L-Q-P-S-L-K-D-S-N-L-N-L-E-E-V-E-K-S-I-L-G-R-Q-N-E-A-E-D-Q-S-L-S-Q-L-G-R-S-R-L-D-A-H-S-R-I-K-R-S-D-Y-I-R-Y-S-D-R-C-C-N-V-G-C-T-R-K-E-L-A-D-L-C"} +{"text": "### FUNCTION Thyroid hormone-binding protein Probably transports thyroxine from the bloodstream to the brain ### SEQUENCE -M-A-S-H-R-L-F-L-L-C-L-A-G-L-V-F-M-S-E-A-G-P-T-G-Q-S-K-C-P-L-M-V-K-V-L-D-A-V-R-G-S-P-A-V-N-V-A-V-K-V-F-K-K-A-A-D-E-T-W-E-P-F-A-S-G-K-T-S-E-S-G-E-L-H-G-L-T-T-D-E-K-F-V-E-G-V-Y-K-V-E-L-D-T-K-S-Y-W-K-T-L-G-I-S-P-F-H-E-Y-V-E-V-V-F-T-A-N-D-S-G-Q-R-R-Y-T-I-A-A-L-L-S-P-Y-S-Y-S-T-T-A-L-V-S-D-P-K-E"} +{"text": "### FUNCTION Thought to form a receptor-activated non-selective calcium permeant cation channel Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors Has also been shown to be calcium-selective May also be activated by intracellular calcium store depletion ### SEQUENCE -F-I-Y-C-L-V-L-L-A-F-A-N-G-L-N-Q-L-Y-F-Y-Y-E-T-R-A-I-D-E-P-N-N-C-K-G-I-R-C-E-K-Q-N-N-A-F-S-T-L-F-E-T-L-Q-S-L-F-W-S-V-F-G-L-L-N-L-Y-V-T-N-V-K-A-R-H-E-F-T-E-F-V-G-A-T-M-F-G-T-Y-N-V-I-S-L-V-V-L-L-N-M-L-I-A-M-M-N-N-S-Y-Q-L"} +{"text": "### FUNCTION Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis ### SEQUENCE -T-A-A-Y-V-R-I-L-Q-R-M-T-S-S-V-A-P-A-S-Q-R-S-I-R-L-R-T-K-R-V-T-R-T-A-I-A-I-C-L-V-F-F-V-C-W-A-P-Y-Y-V-L-Q-L-T-Q-L-S-I-S-R-P-T-L-T-F-V-Y-L-Y-N-A-A-I-S-L-G-Y-A-N-S-C-L-N-P-F-V-Y-I-V-L-C-E-T-F-R-K-R-L-V-L-S-V-K-P-A-A-Q-G-Q-L-R-A-V-S-N-A-Q-T-A-E-E"} +{"text": "### FUNCTION May be involved in the energy metabolism of the mature sperm ### SEQUENCE -M-C-Q-V-E-F-E-M-A-C-A-A-I-K-Q-L-K-G-P-V-S-D-Q-E-K-L-L-V-Y-S-Y-Y-K-Q-A-T-Q-G-D-C-N-I-P-A-P-P-A-T-D-L-K-A-K-A-K-W-E-A-W-N-E-N-K-G-M-S-K-M-D-A-M-R-I-Y-I-A-K-V-E-E-L-K-K-N-E-A-G"} +{"text": "### FUNCTION Modulates injury-induced and chemical pain hypersensitivity Ligand of FPR1, can chemoattract macrophages, promote phagocytosis and increase ROS release ### SEQUENCE -M-R-S-P-R-M-R-A-C-A-K-S-V-L-L-S-H-W-V-F-L-A-Y-V-L-M-V-C-C-K-L-M-S-A-S-S-Q-H-L-R-G-H-A-G-H-H-Q-I-K-Q-G-T-C-E-V-V-A-V-H-R-C-C-N-K-N-R-I-E-E-R-S-Q-T-V-K-C-S-C-F-P-G-Q-V-A-G-T-T-R-A-Q-P-S-C-V-E-A-S-I-V-I-Q-K-W-W-C-H-M-N-P-C-L-E-G-E-D-C-K-V-L-P-D-Y-S-G-W-S-C-S-S-G-N-K-V-K-T-T-K-V-T-R"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-Q-A-L-R-V-S-R-A-L-I-R-S-F-N-T-T-A-R-N-R-F-Q-N-R-V-P-E-K-Q-K-L-F-Q-E-D-N-D-I-P-L-Y-L-K-G-G-I-V-D-N-I-L-Y-R-V-T-M-G-L-C-L-G-G-S-A-Y-S-M-Y-C-L-G-W-A-S-F-P-R-N"} +{"text": "### FUNCTION Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids May activate the TOR signaling cascade in response to amino acids ### SEQUENCE -M-L-K-Q-K-A-L-V-D-V-L-G-Q-V-N-T-S-G-V-D-G-S-W-L-F-N-K-E-G-L-L-L-A-Y-V-G-S-E-Q-K-A-V-A-S-N-V-S-S-A-L-I-A-S-V-W-A-A-L-E-R-R-A-N-D-L-K-E-T-I-L-V-L-E-N-G-V-I-G-C-T-L-V-A-R-T-M-L-L-A-V-K-A-D-K-S-A-D-L-G-M-V-R-A-K-L-H-T-L-A-A-Y-L-E-Q-P-I-L-S-I-S-H-D-L-G"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-S-L-K-A-W-L-G-I-D-K-I-Q-K-F-G-Q-M-V-K-E-I-G-G-V-K-A-V-L-K-K-R-Y-L-M-D-A-T-R-V-G-T-L-V-G-S-D-N-F-G-N-R-Y-Y-E-N-N-A-Y-F-V-P-R-N-R-W-V-E-F-P-D-K-V-W-L-D-Y-D-A-T-Q-V-P-P-E-W-H-S-W-L-H-H-I-T-D-D-A-P-S-V-K-P-P-P-T-Q-D-W-V-L-E-H-K-E-N-T-S-I-Y-A-D-K-K-Y-V-P-Y-S-T-T-R-T-K-I-Q-G-W-Q-P-G-E-K-P-Q-F-D"} +{"text": "### FUNCTION Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules ### SEQUENCE -M-T-E-T-S-T-V-S-I-A-S-S-A-I-V-C-V-E-A-D-I-K-G-E-V-I-I-K-E-G-C-V-V-H-P-F-V-V-F-D-A-T-K-G-P-I-Y-V-G-E-N-N-I-F-E-E-Y-A-V-I-R-N-N-S-D-G-Q-P-M-I-I-G-D-W-N-I-F-Q-V-H-S-K-S-S-A-K-Y-V-G-S-R-N-V-I-G-V-H-A-V-L-E-D-G-C-S-V-S-D-D-C-S-V-G-A-K-C-T-V-F-S-H-Q-N-L-E-P-S-V-S-V-Y-A-A-T-N-L-S-R-T-T-K-T-P-N-M-T-S-P-H-Q-I-E-F-L-R-K-I-L-P-S-Y-H-H-L-Y-G-K-K-K-A-V-A-T-A-S-A-S-A-A-Q"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-N-E-P-S-A-C-S-G-P-P-V-K-S-K-S-S-K-N-E-P-F-Y-T-L-K-A-L-L-P-P-Y-S-E-I-Q-G-N-H-D-L-L-M-S-Y-E-L-G-P-V-E-G-G-F-S-G-S-R-R-V-K-E-K-I-S-S-F-L-P-H-I-I-G-E-F-H-L-D-A-T-K-E-A-S-S-L-R-A-L-I-E-K-P-P-I-H-K-E-I-S-N-L-T-S-S-S-M-Q-G-F-K-L-S-A-G-P-V-D-E-R-Y-R-H-L-F-E-R-R-K-E-E-P-N-L-A-Y-S-E-K-L-N-L-I-R-V-R-Q-Q-Y-D-A-Y-G-F-D-D-D-E-T-E-K-G-F-P-K-K-H-K-K-K-K-K-D-K-K-R-K-K-E-K-E-E-L-G-D-A-E-K-R-K-R-A-A-D-E-P-M-E-F"} +{"text": "### FUNCTION Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane ### SEQUENCE -M-A-P-G-A-S-A-P-A-A-S-R-S-E-D-E-V-G-Q-K-I-D-R-C-F-A-D-S-L-L-K-V-T-G-G-V-A-I-G-I-V-A-S-V-A-F-F-K-S-R-S-W-P-I-W-F-G-S-G-V-G-L-G-T-G-W-S-N-C-R-H-D-F-A-S-P-Y-V-L-H-G-K-R-V-P-A-G-Q-D-S-Q-G-K-P-A-Y-N-I-I-T-E-Q-H-K-Q"} +{"text": "### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-G-V-T-W-V-F-E-A-E-Q-T-A-K-S-V-E-R-L-L-E-S-I-G-G-D-L-H-G-T-F-I-V-D-V-T-P-F-N-P-P-T-P-S-S-D-Y-P-S-N-V-V-M-H-H-S-K-C-P-Q-S-T-F-S-I-C-P-K-D-T-F-K-K-S-P-K-A-V-C-D-R-G-F-D-L-I-L-S-K-L-S-S-G-L-I-A-D-N-A-G-K-I-E-I-I-G-N-E-Y-S-L-Y-K-D-W-M-I-R-V-G-T-A-T-Q-G-T-T-V-K-G-V-V-V-E-I-E-Y-D-P-S-I-I-V-I-Q-C-K-D-M-M-I-E-F-V-K-S-V-F-N-K-Y-H-E-T-L-P-E-I-F-K-I-T-E-K-P-E-S-Y-T-A-L-D-T-M-W-Q-Y-L-G-I-A-T-K-L-R-K-K-T"} +{"text": "### FUNCTION Blocks voltage-gated potassium channels ### SEQUENCE -M-Q-R-N-L-V-V-L-L-F-L-G-M-V-A-L-S-S-C-G-L-R-E-K-H-F-Q-K-L-V-K-Y-A-V-P-E-G-T-L-R-T-I-I-Q-T-A-V-H-K-L-G-K-T-Q-F-G-C-P-A-Y-Q-G-Y-C-D-D-H-C-Q-D-I-K-K-E-E-G-F-C-H-G-F-K-C-K-C-G-I-P-M-G-F"} +{"text": "### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit of the SDH catalytic dimer ### SEQUENCE -M-T-S-R-I-L-Q-R-F-F-T-V-S-T-S-L-R-S-L-T-R-A-E-V-P-G-E-K-I-D-A-K-R-A-R-L-L-Y-Q-S-K-K-R-G-I-L-E-N-D-I-L-L-G-D-F-A-E-Q-N-L-K-K-M-S-E-P-E-L-K-A-Y-D-K-L-I-N-G-E-H-M-E-W-D-L-F-Y-Y-L-S-N-K-K-S-P-P-E-D-V-E-S-C-Q-V-Y-Q-K-V-K-K-F-V-D-D-K-R-V-P-K-S"} +{"text": "### FUNCTION Its target is unknown, but this toxin may modulate voltage-activated calcium channels ### SEQUENCE -M-G-K-L-T-I-L-V-L-V-A-A-V-L-L-S-T-Q-A-M-A-Q-G-D-G-D-Q-P-A-A-R-N-A-V-P-R-D-D-N-P-D-G-P-S-A-K-F-M-N-V-Q-R-R-S-G-C-P-W-E-P-W-C-G"} +{"text": "### FUNCTION Endoribonuclease ### SEQUENCE -M-V-L-Y-F-S-P-V-L-T-F-F-L-A-N-F-F-N-S-K-S-T-T-T-E-N-L-Q-V-F-L-V-E-N-Q-H-R-D-S-K-R-K-I-N-P-T-F-S-K-K-G-I-E-V-R-Q-Q-N-E-N-L-W-S-K-I-V-A-L-R-F-D-Y-S-V-W-G-I-I-Q-L-V-L-M-M-G-L-F-F-Y-I-N-S-V-A-L-I-E-D-L-P-I-D-E-E-F-N-S-V-E-E-F-Y-T-A-A-T-S-A-Y-N-Q-N-A-Y-T-V-G-L-P-V-H-L-C-A-Y-A-S-I"} +{"text": "### FUNCTION TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation TFIIA in a complex with TBP mediates transcriptional activity ### SEQUENCE -M-E-K-P-N-Y-Q-L-Y-R-N-T-T-L-G-Q-A-L-Q-K-T-L-D-D-F-V-G-D-Q-M-I-P-D-S-L-S-K-K-I-M-D-S-F-D-K-S-I-N-K-I-L-P-H-K-A-K-N-K-V-N-F-R-A-D-K-L-R-A-Y-R-Y-C-D-N-V-W-T-F-I-V-E-Q-I-D-L-R-D-A-V-E-G-G-T-V-D-R-L-K-I-V-A-C-D-G-Q-T-K-G-Q-I-G-H-A"} +{"text": "### FUNCTION Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level Has a secretagogue action over the amylase released from the midgut gland May act as a stress hormone and may be involved in the control of molting and reproduction ### SEQUENCE -M-V-A-F-R-M-M-S-M-A-L-L-V-V-V-A-S-S-W-W-A-S-P-V-E-A-A-S-S-P-R-V-D-H-R-L-V-R-R-S-L-F-D-P-S-C-T-G-V-F-D-R-E-L-L-G-R-L-N-R-V-C-D-D-C-Y-N-V-F-R-E-P-K-V-A-T-E-C-R-S-H-C-F-L-N-P-A-F-I-Q-C-L-E-Y-I-I-P-E-V-L-H-E-E-Y-Q-A-N-V-Q-L-V-G-K"} +{"text": "### FUNCTION Oxygen-binding protein The oxygen-binding site contains two iron atoms ### SEQUENCE -M-A-T-T-I-P-S-P-F-N-W-D-S-S-F-C-V-G-N-N-E-L-N-E-Q-H-K-K-L-F-A-L-I-N-A-L-D-A-N-R-S-S-A-S-A-L-K-E-L-L-D-F-V-V-M-H-F-K-A-E-E-D-L-F-A-K-V-N-F-S-D-S-T-S-H-K-E-T-H-D-K-F-V-Q-D-A-L-G-L-K-T-V-G-D-A-E-I-Q-F-I-K-Q-W-L-V-N-H-I-K-G-S-D-M-K-Y-K-G-V-L"} +{"text": "### FUNCTION Ornithine decarboxylase antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome ### SEQUENCE -M-S-S-S-I-V-L-S-N-N-N-S-N-S-N-S-M-S-M-I-G-Q-S-P-P-C-C-S-D-V-P-N-T-P-A-S-E-E-M-T-R-M-V-K-N-V-V-A-S-W-E-W-V-P-L-G-K-D-K-V-G-I-I-I-P-A-D-Q-D-H-R-Q-V-H-K-S-R-F-V-D-L-L-E-F-C-D-E-T-M-K-V-K-E-V-I-A-V-F-G-R-A-D-L-T-V-A-A-G-F-P-R-T-L-R-Y-V-G-F-R-V-V-A-P-E-N-F-P-P-T-L-D-A-T-T-H-F-A-M-T-Y-V-V"} +{"text": "### FUNCTION Ornithine decarboxylase antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome ### SEQUENCE -M-S-K-L-A-V-S-S-S-F-S-L-L-C-G-N-C-K-R-G-H-V-G-L-E-C-Y-S-D-V-P-T-N-N-L-L-S-N-E-H-L-H-S-L-E-S-F-V-N-E-V-S-S-E-W-C-C-H-L-V-D-G-N-T-L-A-I-F-L-P-F-D-Q-S-T-W-N-L-S-K-G-A-F-V-S-L-L-E-F-C-E-D-N-L-P-I-K-R-I-L-L-C-L-N-K-I-N-V-D-E-T-V-V-S-C-F-K-Y-L-G-F-S-P-L-H-P-H-L-Y-P-S-C-I-D-S-Q-G-V-F-V-M-V-Y-S-M"} +{"text": "### FUNCTION Ornithine decarboxylase antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome ### SEQUENCE -M-S-S-I-L-S-S-N-F-T-N-K-S-N-Q-L-V-N-E-S-A-V-D-S-S-L-T-A-S-P-C-S-T-Q-P-G-D-V-G-W-C-F-D-A-P-H-G-V-L-T-K-L-P-N-E-T-R-A-I-V-S-A-V-S-P-N-W-R-V-T-S-I-G-E-K-T-L-A-I-M-I-P-H-D-Q-P-V-L-G-I-S-K-K-N-F-V-D-L-L-E-F-A-E-D-K-L-E-M-E-R-V-L-A-V-F-E-K-A-R-I-N-P-T-E-G-F-P-R-T-L-R-Y-V-G-F-R-P-Y-A-I-D-E-H-P-V-H-L-P-A-E-K-Y-F-I-M-S-Y-K-V"} +{"text": "### FUNCTION May be specifically involved in the formation of the nacreous layer ### SEQUENCE -M-A-C-T-L-R-L-T-I-A-A-L-V-L-L-G-I-C-H-L-S-R-P-V-A-A-Y-Q-R-C-S-R-Y-W-Y-S-W-L-P-Y-D-I-E-R-D-R-Y-D-D-G-Y-R-K-C-C-Y-C-R-N-A-W-T-P-W-Q-C-R-E-D-E-Q-F-E-R-M-R-C-G-S-R-Y-Y-T-L-C-C-Y-T-D-D-D-N-G-N-G-N-G-N-G-N-G-Y-G-N-G-N-G-N-G-N-G-N-N-Y-L-K-Y-L-F-G-G-N-G-N-G-N-G-E-Y-W-E-E-Y-I-D-E-R-Y-D-K"} +{"text": "### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase to ubiquinol Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants May act together with SDHAF1 ### SEQUENCE -M-P-G-R-H-V-S-R-V-R-A-L-Y-K-R-V-L-Q-L-H-R-V-L-P-P-D-L-K-S-L-G-D-Q-Y-V-K-D-E-F-R-R-H-K-T-V-G-S-D-E-A-Q-R-F-L-Q-E-W-E-V-Y-A-T-A-L-L-Q-Q-A-N-E-N-R-Q-N-S-T-G-K-A-C-F-G-T-F-L-P-E-E-K-L-N-D-F-R-D-E-Q-I-G-Q-L-Q-E-L-M-Q-E-A-T-K-P-N-R-Q-F-S-I-S-E-S-M-K-P-K-F"} +{"text": "### FUNCTION Candidate tumor suppressor ### SEQUENCE -M-T-M-N-V-L-E-A-G-K-W-K-S-I-V-P-A-P-G-E-G-L-L-A-V-L-H-M-M-V-F-T-D-A-L-H-R-E-R-S-V-K-W-Q-A-G-V-C-Y-N-G-G-K-D-F-A-V-S-L-A-R-P-K-A-A-E-G-I-A-D"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-F-G-L-G-G-A-P-Q-I-S-S-E-Q-K-L-Q-A-A-E-A-E-L-D-M-V-T-G-M-F-N-Q-L-V-D-Q-C-H-S-K-C-I-N-K-S-Y-G-D-S-D-I-T-K-Q-E-A-L-C-L-D-R-C-V-A-K-Y-F-D-T-N-V-Q-V-G-E-H-M-Q-K-L-G-Q-S-G-Q-F-M-G-R-K"} +{"text": "### FUNCTION Probable methyltransferase ### SEQUENCE -M-N-L-L-Q-L-G-K-L-H-E-N-V-L-D-A-G-C-E-P-N-R-N-A-R-Y-L-A-S-L-G-Y-K-V-V-G-I-D-I-S-E-R-A-I-S-K-A-I-D-K-T-S-S-E-K-S-N-V-N-F-N-Q-R-D-F-S-R-L-N-E-F-K-G-H-F-D-T-V-I-D-I-G-C-F-H-S-I-L-N-S-D-H-E-P-Y-T-A-S-L-S-H-I-C-H-S-D-S-S-V-F-L-R-A-F-S-E-T-N-K-S-R-Y-R-R-W-Q-G-H-K-R-Y-S-L-A-L-K-R-N-N-V-K-K-L-S-L"} +{"text": "### FUNCTION Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 ### SEQUENCE -M-S-A-L-Q-A-Y-R-H-L-M-R-A-A-R-V-A-F-D-G-D-N-R-T-L-T-A-A-Y-E-S-I-R-R-G-F-R-E-N-Q-N-V-P-A-N-D-P-T-I-A-P-A-I-A-H-A-E-E-V-A-S-F-L-R-S-N-V-V-Q-G-R-K-D-G-E-T-Y-K-L-R-I-H-Q-D-T-E-R-G-D-N-D-T-I-K-L-G-N-Q-T-I-K-I-G-G-E-Q-K-C-C-S-A"} +{"text": "### FUNCTION Probable methyltransferase ### SEQUENCE -M-N-L-V-Q-L-G-K-L-H-E-N-V-L-D-A-G-C-E-P-N-R-N-A-R-Y-L-A-S-L-G-Y-K-V-V-G-I-D-I-S-E-R-A-I-S-K-A-I-D-K-T-S-S-E-K-S-N-V-N-F-N-Q-R-D-F-S-R-L-N-E-F-K-G-H-F-D-T-V-I-D-I-G-C-F-H-S-I-L-N-S-D-H-E-P-Y-T-A-S-L-S-H-I-C-H-S-D-S-S-V-F-L-R-A-F-S-E-T-N-K-S-R-Y-R-R-W-Q-G-H-K-R-Y-S-L-A-L-K-R-N-N-V-K-K-L-S-L"} +{"text": "### FUNCTION Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems ### SEQUENCE -M-A-H-V-L-P-D-L-P-Y-A-Y-D-A-L-E-P-Y-I-S-R-Q-I-M-E-L-H-H-K-K-T-S-S-D-L-C-E-C-A-Q-H-C-R-G-C-L-R-H-S-T-A-V-V-G-G-F-D-L-S-L-F-F-I-L-T-T-L-G-H-I-N-H-S-L-F-W-Q-N-L-A-P-A-A-G-A-G-G-Q-L-K-P-G-P-L-K-D-A-I-D-Q-T-F-G-G-L-D-N-L-K-K-E-F-N-T-T-T-A-G-I-Q-G-S-G-W-G-W-L-G-V-N-P-S-N-K-R-L-E-I-S-T-T-P-N-Q-D-P-L-L-N-L-V-P-I-I-G-V-D-I-W-E-H-A-F-Y-L-Q-Y-L-N-V-K-A-D-Y-L-N-A-I-W-S-V-I-N-F-D-E-A-Q-R-R-Y-V-E-A-T-Q-G-S-K-L"} +{"text": "### FUNCTION Forms a chaperone-bound H2AZ-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2AZ histone replacement in chromatin ### SEQUENCE -M-S-T-E-N-G-T-T-D-T-T-L-A-G-T-A-E-A-N-T-P-F-E-S-K-G-K-G-K-A-A-A-E-S-E-D-H-P-M-G-E-A-E-D-D-E-D-D-E-D-E-D-E-T-E-E-P-E-A-E-E-D-N-L-E-E-I-D-P-S-N-V-I-S-G-P-R-T-R-Q-K-E-I-D-Y-A-K-A-A-Q-D-L-P-A-E-E-D-D-E-E-D-D-E-E-F-V-P-E-D-E-E-M-E-E"} +{"text": "### FUNCTION Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases ### SEQUENCE -M-S-A-E-F-T-Y-Q-D-V-A-E-H-N-T-K-K-D-L-Y-V-V-I-H-D-K-V-Y-D-I-T-K-F-V-D-E-H-P-G-G-E-E-V-L-L-D-V-A-G-Q-D-S-T-E-A-F-E-D-V-G-H-S-D-E-A-R-E-A-L-E-P-L-L-V-G-T-L-K-R-Q-A-G-D-P-K-P-K-A-P-L-P-S-S-L-A-P-A-A-Q-T-G-T-A-T-G-L-G-I-G-L-Y-A-V-L-V-L-G-G-L-A-G-F-A-A-Y-Q-Y-L-Q-A-Q-Q-G-A-T-A-P-S-A"} +{"text": "### FUNCTION Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control ### SEQUENCE -M-T-S-V-A-Q-R-Q-A-Q-P-A-Q-P-S-T-S-Q-T-A-A-P-T-R-T-Q-T-E-T-S-S-P-A-I-L-R-L-R-G-A-H-S-N-G-R-S-V-Q-W-R-S-D-V-V-D-N-E-G-L-G-R-K-K-S-K-V-C-C-I-Y-H-R-P-K-G-V-D-E-S-S-D-D-S-S-S-S-S-D-S-S-S-S-S-D-S-D-S-D-P-E-P-D-Q-D-K-R-I-T-S-G-G-G-S-S-G-R-G-H-R-H-S-H-D-H-D-H-D-G-R-E-G-G-C-N-H-D-H-G-R-G-R-K-H-G-N-K-G-K-K-T-E-R-R-P-S-P-N-A-Y-E-K-M-P-K-Y-K-P-K-D-G-G-A-G-P-S-N-S-E-T-Q-G-P-G-G-S-K"} +{"text": "### FUNCTION Has a role in meiosis ### SEQUENCE -M-M-K-L-E-N-K-L-H-R-V-L-C-S-L-H-Q-N-S-I-S-T-H-K-T-Y-V-A-V-A-A-Q-D-E-Y-V-R-M-G-K-V-S-L-P-R-M-Y-A-V-K-P-R-I-Q-K-N-F-Q-D-N-Y-R-F-Y-G-T-L-L-C-I-C-W-L-Y-F-F-I-W-Y-P-F-A-L-L-A-L-M-V-G-V-F-L-S-F-V-M-H-G-L-G-S-L-T-I-N-Q-N-I-R-L-D-P-K-Y-S-I-P-G-V-C-A-V-T-L-I-V-I-M-F-L-A-P-V-G-R-L-F-W-S-F-C-I-V-S-S-F-A-G-L-H-C-L-L-T-T-Y-E-N-P-A-G-I-L"} +{"text": "### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane mS38 is also involved in the splicing of the COX1 mRNA ### SEQUENCE -M-L-R-R-G-A-L-S-T-I-L-K-G-L-N-G-L-S-L-R-S-P-I-P-I-W-H-V-S-A-S-P-E-V-G-S-K-Y-N-L-P-T-V-P-T-T-S-H-V-S-Y-R-Q-I-A-K-A-N-F-F-A-G-Y-R-P-L-S-A-N-Q-I-C-V-P-K-V-E-S-K-T-Q-V-S-Q-S-Q-D-E-E-D-Q-P-Q-E-Y-V-L-S-L-E-D-G-Y-L-Y-A-Q-S-F-S-A-S-G-S-V-T-Q-T-Q-P-A-R-I-S-T-Q-V-W-E-Q-I-C-D-K-L-I-S-I-T-P-L-D-L-T-S-V-K-R-K-R-K-L-K-M-N-K-H-K-F-K-K-R-L-R-R-Q-R-A-L-R-K-R-L-G-K"} +{"text": "### FUNCTION Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 ### SEQUENCE -M-I-L-P-L-F-P-E-T-Q-V-H-V-F-V-Y-E-N-V-S-N-C-A-A-I-H-E-Q-L-I-S-Q-N-P-I-Y-D-Y-A-F-L-D-A-A-T-I-L-Y-K-K-Q-V-Y-S-A-I-I-R-A-L-E-D-R-R-D-E-Q-M-K-T-K-T-I-H-S-E-V-I-L-S-L-S-P-K-T-E-I-S-S-A-F-R-Q-F-S-M-T-K-K-S-K-N-I-V-V-V-K-I-D-S-K-L-T-E-E-E-E-F-E-R-L-D-K-L-V-E-G-N-R-V-E-F-S-D-E-E-L-Q-K-L-I-D-F-K-V-L-K-K-N-Y-K-L-D-P-S-T-L-E-N-P-L-A-S-I-L-S-S-I-A-L-R-G-Y-S"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-D-R-L-N-V-K-E-Q-E-H-L-T-Q-V-L-E-A-K-Q-L-K-E-Y-L-N-M-Y-S-T-L-T-Q-N-C-F-S-D-C-V-Q-D-F-T-S-S-K-L-S-N-K-E-S-E-C-I-A-K-C-A-D-K-F-L-K-H-S-E-R-V-G-Q-R-F-A-E-F-N-A-K-Y-M-G-Q"} +{"text": "### FUNCTION May play a role in RNA metabolism ### SEQUENCE -M-S-S-S-K-A-N-Q-T-R-V-C-Y-Q-P-E-D-T-T-F-I-I-I-A-S-N-G-P-D-V-M-R-W-R-K-D-K-T-V-P-L-T-E-I-V-D-S-F-Q-V-F-T-T-S-N-N-K-G-N-E-G-Q-L-I-T-A-S-K-Q-E-L-E-N-T-F-G-T-S-K-D-V-D-V-V-T-K-I-L-T-D-G-K-I-I-P-H-R-E-H-G-K-H-K-E-V-N"} +{"text": "### FUNCTION Probable methyltransferase ### SEQUENCE -M-N-L-V-Q-L-G-K-L-H-E-N-V-L-D-A-G-C-E-P-N-R-N-A-R-Y-L-A-S-L-G-Y-K-V-V-G-I-D-I-S-E-R-A-I-S-K-A-I-D-K-T-S-S-E-K-S-N-V-N-F-N-Q-R-D-F-S-R-L-N-E-F-K-G-H-F-D-T-V-I-D-I-G-C-F-H-S-I-L-N-S-D-H-E-P-H-T-A-S-L-S-H-I-C-H-S-D-S-S-V-F-L-R-A-F-S-E-T-N-K-S-R-Y-R-R-W-Q-G-H-K-R-Y-S-L-A-L-K-R-N-N-V-K-K-L-S-L"} +{"text": "### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase to ubiquinol Promotes maturation of the iron-sulfur protein subunit sdh2 of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants May act together with SDHAF1 ### SEQUENCE -M-N-N-I-T-K-L-M-K-Q-K-N-I-L-T-P-P-L-P-L-Y-R-R-V-L-R-A-H-R-Y-H-L-G-A-E-E-R-A-L-G-D-E-Y-V-K-A-E-F-R-R-H-R-N-V-T-N-P-L-H-L-V-G-F-L-S-S-W-E-R-Y-A-D-A-L-E-N-E-S-W-K-Q-E-K-Y-S-N-T-D-L-L-E-S-L-N-D-Q-Q-I-G-Q-L-Y-E-L-S-K-A-L-Q-E-Q-K-K-S-E"} +{"text": "### FUNCTION Functions together with the other V-type ATPase assembly factors in the endoplasmic reticulum to efficiently assemble the V-type ATPase membrane sector V ### SEQUENCE -M-S-Y-W-V-E-L-W-E-S-I-F-T-P-G-V-T-P-V-L-A-K-S-A-H-V-A-C-G-A-L-V-A-V-F-L-G-L-Y-I-G-T-K-S-I-H-C-L-I-L-F-F-L-A-I-C-L-W-L-S-L-T-W-F-L-V-E-L-A-H-A-R-V-N-N-D-L-Q-M-S-S-Q-S-A-N-K-N-D-D-N-S-N-N-Q-N-P-S-N-N-K-E-M-S-D-K-E-S-D-S-A-T-T-T-Q-T-F-S-V-P-E-E-L-L-R-A-R-T-T-A-N-N-S"} +{"text": "### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane ### SEQUENCE -M-S-I-M-K-P-T-T-R-F-F-R-F-N-S-L-E-L-A-V-S-P-F-Q-R-I-Y-G-Q-L-R-F-L-R-K-Q-P-K-P-F-L-V-K-L-L-N-N-E-V-S-K-L-G-R-Q-G-D-V-V-S-V-T-R-G-Y-Y-R-N-T-L-F-P-K-K-Q-A-I-A-V-D-A-L-K-S-M-K-A-H-L-L-Q-G-S-E-F-S-T-K-T-K-E"} +{"text": "### FUNCTION Plays a role in the regulation of membrane potential ### SEQUENCE -M-N-S-E-K-I-I-E-V-I-I-A-I-F-L-P-P-V-A-V-F-M-K-C-G-A-T-T-P-L-W-I-N-L-V-L-C-I-F-I-W-F-P-A-I-L-H-A-L-Y-V-V-L-K-D"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -E-G-T-P-S-L-G-K-R-H-N-K-S-H-T-L-C-N-R-C-G-R-R-S-F-H-V-Q-K-K-T-C-S-S-C-G-Y-P-A-A-K-M-R-S-H-N-W-A-L-K-A-K-R-R-R-T-T-G-T-G-R-M-A-Y-L-K-H-V-T-R-R-F-K-N-G-F-Q-T-G-V-A-K-A-Q-T-P-S-A"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-I-T-D-E-Q-L-N-T-I-A-L-T-F-G-F-A-S-I-I-L-I-I-I-Y-H-A-I-S-T-N-V-H-K-L-E-D-E-T-P-S-S-S-F-T-R-T-N-T-T-E-T-T-V-A-S-K-K-K-K"} +{"text": "### FUNCTION The complex LTO1YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly complex machinery May be required for biogenesis of the large ribosomal subunit and initiation of translation ### SEQUENCE -M-T-C-Q-E-D-C-S-C-K-N-N-E-A-P-T-T-K-T-T-A-T-T-T-N-V-G-D-G-P-G-P-G-P-I-P-G-N-N-D-D-D-D-D-D-I-W-S-D-D-D-T-K-L-I-P-E-N-D-I-I-R-S-H-Y-K-K-G-Y-V-D-G-I-T-Q-A-K-E-S-S-L-Q-Q-G-F-D-D-G-Y-P-E-G-A-K-L-G-I-K-V-G-E-I-L-A-N-L-I-N-Q-C-K-D-R-N-R-Q-G-D-D-D-D-D-D-D-D-E-Q-S-V-R-F-N-E-A-K-K-E-L-N-I-V-N-V-L-K-K-S-Y-F-D-E-D-L-N-L-K-K-S-N-D-N-K-E-T-D-E-S-Y-H-E-L-I-N-K-W-E-N-E-M-K"} +{"text": "### FUNCTION Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits Has a physiological role leading to 18S rRNA stability ### SEQUENCE -M-E-N-D-K-G-Q-L-V-E-L-Y-V-P-R-K-C-S-A-T-N-R-I-I-K-A-K-D-H-A-S-V-Q-I-S-I-A-K-V-D-E-D-G-R-A-I-A-G-E-N-I-T-Y-A-L-S-G-Y-V-R-G-R-G-E-A-D-D-S-L-N-R-L-A-Q-Q-D-G-L-L-K-N-V-W-S-Y-S-R"} +{"text": "### FUNCTION Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH At alkaline ambient pH, activates transcription of alkaline-expressed genes ### SEQUENCE -V-C-E-R-H-V-G-R-K-S-T-N-N-L-N-L-T-C-Q-W-G-S-C-R-T-T-T-V-K-R-D-H-I-T-S-H-I-R-V-H-V-P-L-K-P-H-K-C-D-F-C-G-K-A-F-K-R-P-Q-D-L-K-K-H-V-K-T-H-A-D-D"} +{"text": "### FUNCTION Facilitates protein transport into the nucleus Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import ### SEQUENCE -M-S-V-D-F-N-A-V-A-T-E-F-C-N-F-Y-Y-N-Q-F-D-S-D-R-S-Q-L-G-N-L-Y-R-N-E-S-M-L-T-F-E-T-S-Q-L-Q-G-A-R-D-I-V-E-K-L-A-S-L-P-F-Q-K-V-A-H-R-I-S-T-L-D-A-Q-P-A-S-A-N-G-D-I-L-V-M-V-T-G-E-L-L-I-D-E-E-Q-N-A-Q-R-Y-S-Q-V-F-H-L-I-P-D-N-G-S-Y-Y-V-F-N-D-I-F-R-L-N-Y-S"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-E-P-E-I-K-I-V-N-V-V-V-S-T-Q-I-G-T-D-I-D-L-E-Y-A-A-D-I-L-D-N-A-E-Y-E-P-E-Q-F-P-G-L-V-C-R-L-S-D-P-K-V-A-L-L-I-F-R-S-G-K-L-N-C-T-G-A-K-S-K-E-D-A-E-I-A-I-K-K-I-I-K-E-L-K-D-A-G-M-D-I-I-D-N-P-E-V-N-V-Q-N-M-V-A-T-A-D-L-G-I-E-P-N-L-D-D-I-S-T-L-E-G-T-E-Y-E-P-E-Q-F-P-G-L-V-Y-R-L-S-D-P-K-V-V-V-L-I-F-G-S-G-K-V-V-I-T-G-L-K-K-K-D-D-A-Y-L-A-L-D-K-I-L-S-T-L-K-E-L-E-E-E-Y-Y"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-S-C-K-R-F-P-R-S-A-R-I-C-L-R-S-E-Y-Y-V-A-F-E-Q-G-R-R-Y-S-S-V-L-L-R-L-H-H-L-P-T-S-G-P-V-R-L-G-L-V-V-S-R-R-V-D-I-R-A-V-N-R-N-R-I-K-R-A-L-R-E-V-M-R-Q-I-A-Y-K-L-V-P-G-D-Y-V-V-V-V-R-Q-T-A-K-D-V-S-N-A-E-L-S-V-A-L-L-S-L-L-R-R-I-G-A-L-P-L-A-P-I-D-N-A-M-L-P-F-F-E-R-N-C-S-R-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-L-G-L-R-L-I-V-G-L-G-N-P-G-S-E-H-T-K-T-R-H-N-A-G-F-R-F-V-D-G-L-V-Q-R-E-G-Q-R-W-M-L-E-S-K-L-F-A-H-V-A-R-V-F-I-A-G-Q-W-V-W-L-L-R-P-V-T-F-M-N-L-S-G-K-S-I-C-A-G-L-S-F-W-K-I-K-P-E-Q-M-L-V-A-H-D-E-L-D-F-P-P-G-A-V-R-L-K-F-D-G-G-H-G-G-Q-N-G-L-R-D-I-T-K-L-L-G-H-G-R-F-H-R-L-R-V-G-I-G-H-P-G-H-K-D-R-V-V-N-W-V-L-G-C-P-T-C-E-E-N-I-A-I-D-A-A-L-E-R-A-S-A-V-L-P-L-V-V-A-G-D-F-D-E-A-M-K-K-L-H-T-V-V"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-K-R-W-Y-V-V-H-A-Y-S-G-F-E-K-S-V-A-Q-A-L-R-D-R-I-S-R-I-E-I-Q-D-R-F-G-D-V-L-V-P-A-E-E-V-V-E-M-R-S-G-Q-K-R-R-S-E-H-K-F-F-P-G-Y-V-L-I-Q-I-E-T-Y-Y-E-G-G-V-P-R-I-D-N-E-C-W-H-L-V-K-E-T-P-K-V-M-G-F-I-G-G-T-A-D-R-P-L-P-I-S-S-D-E-A-D-A-I-L-R-R-V-Q-D-G-A-E-K-P-R-P-K-V-L-F-E-P-G-Q-M-V-R-V-I-D-G-P-F-N-D-F-D-G-L-V-E-E-V-N-Y-E-K-N-R-L-R-V-A-V-L-I-F-G-R-P-T-P-V-D-L-E-F-G-Q-V-Q-K-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-I-A-Y-I-K-L-Q-V-K-A-G-Q-A-S-P-S-P-P-V-G-P-A-L-G-Q-R-G-L-N-I-M-D-F-C-K-A-F-N-A-A-T-Q-K-V-E-Q-G-L-P-I-P-V-V-I-T-A-Y-S-D-R-T-F-T-F-I-T-K-T-P-P-A-S-I-L-L-K-K-I-V-G-I-Q-S-G-S-K-R-P-N-T-E-K-V-G-K-V-T-R-K-Q-L-E-D-I-A-K-T-K-E-L-D-M-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-V-V-E-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-I-F-Q-K-Q-E-V-V-E-E-L-A-G-V-A-T-K-A-H-S-L-I-V-A-E-Y-A-G-I-T-V-S-Q-M-T-A-M-R-K-Q-A-R-E-S-G-V-Y-L-K-V-V-K-N-K-L-A-A-R-A-L-G-D-T-E-Y-A-V-I-K-E-K-L-I-G-P-L-L-Y-A-F-S-L-E-D-P-G-A-A-G-R-L-I-K-E-F-S-K-K-H-D-K-L-K-S-K-T-V-S-L-G-G-V-L-Y-P-A-G-H-V-D-V-L-A-S-L-P-T-R-L-Q-A-L-A-M-L-A-R-V-L-S-E-P-V-T-L-F-A-R-A-I-K-A-V-A-D-D-K-S-E-T-V-A-V-S-A-P-E-A-S-Q-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-L-T-N-E-K-I-V-E-A-I-A-E-K-S-I-M-E-V-M-E-L-V-K-A-I-E-D-K-F-G-V-S-A-A-A-P-V-M-V-S-G-S-A-A-A-A-A-P-V-E-E-Q-T-E-F-T-V-T-L-K-E-A-G-A-K-K-V-E-V-I-K-A-V-R-A-V-T-G-L-G-L-K-E-A-K-D-L-T-E-A-G-G-I-L-K-E-A-V-S-K-E-E-A-E-K-V-K-K-E-L-E-A-A-G-A-T-V-E-V-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-G-S-T-P-Q-R-N-V-L-P-D-P-K-Y-G-S-E-T-I-A-R-F-I-N-M-V-M-K-S-G-K-K-S-V-A-E-K-I-V-Y-G-A-M-N-V-I-G-E-K-N-S-N-A-I-E-L-L-Q-K-A-L-D-N-V-S-P-A-V-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-A-S-R-R-M-A-L-A-M-R-W-L-I-D-S-S-R-K-R-G-E-N-S-M-P-H-K-L-A-A-E-L-L-D-A-S-E-S-R-G-G-A-I-K-K-R-E-E-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-Q-I-S-D-R-A-K-A-H-F-L-R-L-I-Q-R-E-G-V-P-G-M-G-V-R-L-S-A-V-D-P-G-T-A-R-A-D-A-R-L-E-F-A-E-P-S-E-L-V-G-D-E-W-L-I-D-C-G-D-F-T-L-Y-V-A-S-A-S-V-A-W-L-D-S-A-E-I-D-Y-V-T-Q-A-T-G-S-Q-Q-L-I-I-K-A-P-K-I-K-G-Q-E-L-S-Q-V-A-S-L-V-E-R-V-C-W-V-V-E-N-E-I-N-P-Q-L-A-S-H-G-G-R-V-E-V-Q-E-V-S-A-E-G-V-V-L-L-R-F-G-G-G-C-H-G-C-G-M-V-D-V-T-L-K-Q-G-V-E-K-T-L-M-E-R-V-H-G-V-I-A-V-R-D-A-T-D-H-S-T-G-A-A-P-Y-I-S-R-N-F-A-S"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-K-F-F-R-R-R-K-F-C-K-F-T-A-E-G-I-K-E-I-D-Y-K-D-L-N-T-L-R-Q-Y-L-T-E-N-G-K-I-V-P-S-R-V-T-G-T-K-S-K-Y-Q-R-Q-L-T-T-A-V-K-R-A-R-F-L-A-L-I-P-Y-T-D-N-H-D-I"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-L-I-L-L-Q-K-V-A-N-L-G-A-L-G-D-K-V-T-V-K-P-G-Y-G-R-N-F-L-L-P-K-G-V-A-V-P-A-T-E-A-N-L-A-A-F-Q-A-K-R-A-E-Y-E-A-K-A-K-S-E-L-D-Q-A-Q-A-R-A-A-K-F-E-G-A-S-V-T-V-S-A-H-A-S-T-E-G-K-L-Y-G-S-V-G-A-R-D-I-A-E-A-F-T-A-V-G-L-P-L-E-K-K-E-V-I-L-G-E-G-P-F-R-L-I-G-E-Y-D-V-L-L-H-L-H-A-D-V-E-S-T-V-K-V-I-V-Q-G-V-P"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-I-L-T-K-R-Q-A-H-L-K-S-D-D-V-D-L-A-V-K-S-L-L-E-M-M-G-G-A-L-S-E-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-P-P-R-C-G-R-N-P-K-T-G-E-S-V-A-L-P-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-E-R-V-A-S-V-V-P-L-A-E-C-G-D-I-T-E"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-L-V-T-G-G-K-Q-Y-R-V-V-Q-G-E-T-L-R-V-E-K-L-D-V-E-T-G-S-D-V-T-F-N-S-V-L-L-M-G-S-S-D-G-I-H-V-G-E-A-L-K-D-A-S-V-T-A-K-V-V-A-H-G-R-A-R-K-V-R-I-I-K-F-R-R-R-K-H-H-M-K-H-Q-G-H-R-Q-Y-Y-T-E-I-Q-I-T-G-I-S-G-P-A-K-Q"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-N-N-K-H-P-E-N-K-A-K-S-T-T-T-P-K-T-I-A-L-N-K-R-A-R-H-E-Y-H-L-I-E-R-H-E-A-G-L-E-L-Q-G-W-E-V-K-A-I-R-A-G-R-A-N-L-A-D-G-Y-A-Y-V-R-D-G-E-I-F-L-I-G-A-Q-I-T-P-L-I-Q-A-S-T-H-V-V-A-N-D-R-R-T-R-K-L-L-L-H-R-R-Q-I-D-T-L-I-G-R-V-Q-R-E-G-F-T-L-V-P-T-A-M-Y-W-S-K-N-R-V-K-M-E-I-A-L-A-K-G-K-Q-A-H-D-K-R-H-A-E-K-E-R-E-W-Q-R-D-K-Q-R-I-M-R-A-H-N-R-N-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-Q-D-H-P-E-C-D-S-E-E-L-T-Q-N-S-P-E-T-D-P-L-K-V-E-V-E-T-L-R-G-E-I-A-S-I-K-A-D-V-L-R-E-R-A-E-L-E-N-Q-R-K-R-L-I-R-D-V-E-Q-A-R-K-F-A-N-E-K-L-L-G-E-L-L-P-V-F-D-S-L-D-A-G-L-T-A-S-G-S-E-P-S-P-L-R-D-G-L-E-L-T-Y-K-Q-L-L-K-V-A-T-D-N-G-L-M-L-L-D-P-V-G-Q-L-F-N-P-E-H-H-Q-A-I-S-Q-T-E-V-T-D-V-E-P-G-Y-V-I-Q-V-F-Q-K-G-Y-L-L-N-E-R-L-L-R-P-A-L-V-V-V-A-K-Q-D"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-S-P-I-T-I-L-L-I-G-I-A-M-S-T-D-A-F-A-A-A-I-G-K-G-A-A-I-G-K-P-R-L-R-D-A-L-Y-V-A-V-I-F-G-V-I-E-T-A-T-P-I-A-G-W-L-L-G-Q-I-A-S-H-Y-I-A-T-F-D-H-W-I-A-F-G-L-L-S-G-L-G-I-H-M-I-V-N-G-L-K-N-N-G-N-T-C-K-D-N-A-D-T-H-N-R-N-S-R-W-L-P-L-A-A-T-A-L-A-T-S-I-D-A-A-A-I-G-I-S-L-A-F-L-D-I-H-I-S-I-V-A-A-V-I-G-L-C-T-F-T-M-V-I-F-G-V-M-L-G-R-V-L-G-T-F-V-G-N-R-A-E-I-V-G-G-I-I-L-I-I-V-G-S-T-I-L-Y-E-H-L-S-N-N-G"} +{"text": "### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-S-R-E-Q-A-F-E-M-L-I-K-I-L-C-K-T-D-S-T-D-D-M-K-L-I-L-E-C-I-L-T-R-S-E-M-E-D-L-I-D-R-I-R-I-Y-N-E-L-L-N-T-N-N-S-Q-R-E-V-A-S-K-L-G-V-S-I-T-K-I-T-R-G-A-A-N-L-Q-D-N-N-I-K-D-F-L-R-K-K-I-S-Y"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-L-R-G-V-L-T-S-K-T-P-P-W-L-V-V-D-V-C-G-V-G-Y-E-L-E-V-P-M-S-T-F-Y-E-L-P-N-V-G-Y-E-V-N-L-F-T-H-Y-T-Q-K-D-D-S-A-A-L-Y-G-F-L-S-E-S-E-R-R-L-F-R-H-L-Q-R-V-S-G-I-G-T-K-I-A-L-A-V-L-S-S-V-S-V-D-T-F-A-G-L-I-Q-A-G-D-V-N-A-L-T-V-I-P-G-I-G-K-K-T-A-E-R-M-L-V-E-L-R-D-R-A-A-D-F-N-N-G-I-S-T-S-G-K-L-N-L-D-T-V-S-E-A-A-L-A-L-Q-Q-L-G-Y-K-P-A-E-A-A-R-M-A-R-D-A-G-T-E-S-D-D-V-A-S-V-I-K-K-A-L-Q-A-A-L-R"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-T-H-L-L-E-Q-L-I-D-A-F-R-I-L-P-G-V-G-Q-K-T-A-Q-R-M-A-Y-H-V-L-E-R-E-R-E-G-G-Q-R-L-A-D-V-L-S-R-A-I-E-K-I-G-H-C-T-E-C-R-D-F-S-E-T-K-I-C-A-I-C-A-N-Y-S-R-D-R-H-Q-L-C-V-V-E-S-P-P-D-R-L-A-I-E-Q-A-T-G-Y-R-G-L-Y-F-I-L-Q-G-R-L-S-P-L-D-G-I-G-P-H-E-L-G-L-D-H-L-G-Q-R-L-A-A-G-E-V-T-E-L-I-I-A-T-N-A-T-V-E-G-E-T-T-A-H-Y-L-A-L-L-A-R-Q-H-G-I-R-P-S-R-L-A-Q-G-L-P-L-G-G-E-L-E-Y-L-D-R-G-T-L-S-H-A-F-G-T-R-T-E-V-V"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-R-G-N-I-A-Q-L-M-Q-Q-A-Q-K-M-Q-E-N-L-Q-R-A-Q-E-E-L-A-K-L-E-V-T-G-S-A-G-G-G-M-V-S-V-I-L-S-G-T-K-E-C-R-K-V-R-I-D-P-S-I-L-N-D-Q-E-M-I-E-D-L-I-A-A-A-F-N-D-A-S-N-K-V-D-T-E-S-K-E-R-M-G-S-A-T-L-G-M-S-L-P-P-G-F-K-L-P-F"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-D-E-I-T-N-G-A-A-K-P-T-E-A-I-S-G-P-T-F-T-I-E-K-I-Y-I-K-D-V-S-F-E-A-P-N-S-P-A-V-F-N-E-A-G-Q-P-E-L-Q-L-N-L-N-Q-R-V-Q-R-L-N-E-N-A-F-E-L-V-L-H-V-T-L-T-C-T-A-A-G-K-T-A-Y-V-V-E-V-Q-Q-A-G-V-F-G-L-F-G-L-D-Q-H-A-I-G-V-L-L-G-T-Q-C-P-N-I-L-F-P-Y-V-R-S-L-V-S-D-L-I-Q-I-G-G-F-P-P-F-Y-L-Q-P-I-N-F-D-A-L-Y-A-E-T-L-R-Q-R-A-Q-N-E-K-E-G-S-Q-I-S-S-H-P-A-G-N-A"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-T-T-F-T-A-K-N-E-T-V-Q-R-D-W-Y-L-V-D-A-E-G-K-T-L-G-R-L-A-T-E-L-A-R-R-L-L-G-K-T-K-P-V-Y-T-T-H-V-D-T-G-D-Y-L-V-V-I-N-A-E-K-V-V-V-T-G-K-K-L-T-D-K-Y-Y-H-R-F-T-G-Y-V-G-N-L-K-S-E-S-L-G-Q-A-L-Q-R-H-P-E-R-V-L-E-I-A-V-K-G-M-L-P-K-G-P-L-G-R-A-M-Y-R-K-L-K-V-Y-T-G-S-K-H-P-H-A-A-Q-Q-P-Q-V-L-D-I"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-V-E-D-C-L-E-V-V-N-N-R-F-E-L-V-M-M-A-S-K-R-A-R-Q-L-A-N-G-V-P-P-L-I-E-N-T-N-S-E-D-K-P-T-V-L-A-L-R-E-I-A-A-R-K-I-D-S-K-M-I-D-E-I-E-K-A-E-R-E-R-T-E-R-E-A-M-E-W-A-A-A-E-V-V-A-D-E-D-M-S-K-S-D-D"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-A-V-V-W-W-Q-S-L-L-L-V-M-L-G-G-A-F-G-S-G-L-R-F-V-I-G-S-C-L-L-Q-R-F-G-A-G-F-P-W-G-T-L-A-V-N-L-I-G-S-F-V-A-G-F-L-L-I-W-L-D-K-R-G-S-A-G-W-S-W-R-M-L-L-I-V-G-L-I-G-G-L-T-T-F-S-S-L-M-M-E-C-L-V-F-V-R-S-D-R-S-L-M-V-G-L-Y-L-C-I-T-L-L-F-G-L-L-F-V-F-L-G-A-R-L-G-A-F-V-C-D-D-Q-R-V-L-E-I-D-R-T-A"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-C-I-E-F-E-G-T-V-S-E-T-L-P-N-T-T-F-R-I-K-L-E-N-G-H-E-V-T-A-H-I-S-G-R-M-R-K-N-Y-I-R-I-L-T-G-D-R-V-K-I-E-M-T-A-Y-D-L-T-K-G-R-I-I-Y-R-M-K"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-Q-K-T-V-H-D-Q-D-N-A-L-L-L-E-T-G-N-T-K-V-A-P-P-P-R-Y-Q-V-L-L-L-N-D-D-Y-T-P-M-D-F-V-I-V-V-L-Q-Q-F-F-A-M-D-L-K-K-A-T-Q-V-M-L-H-V-H-T-R-G-C-G-V-C-G-F-Y-T-R-E-V-A-E-S-K-V-A-Q-V-N-E-F-S-R-I-H-Q-H-P-L-L-C-T-M-K-Q-A"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-L-E-H-E-L-I-V-T-N-K-L-G-L-H-A-R-A-T-A-K-L-V-Q-T-M-S-K-F-Q-S-N-T-T-L-S-T-K-G-R-E-V-N-A-K-S-I-M-G-V-M-L-L-A-A-S-Q-G-T-V-I-R-V-R-I-D-G-E-D-E-H-T-A-M-Q-A-L-S-E-L-F-E-N-R-F-N-E-D-T"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-R-G-I-N-K-V-I-L-V-G-N-L-G-N-D-P-D-I-K-Y-T-Q-G-G-M-T-I-T-T-I-S-L-A-T-T-S-V-R-K-D-K-E-G-N-T-Q-E-R-T-E-W-H-R-V-K-F-F-G-K-L-G-E-I-A-G-E-Y-L-R-K-G-S-Q-C-Y-I-E-G-S-I-R-Y-D-K-F-T-G-Q-D-G-Q-E-R-Y-V-T-E-I-V-A-D-E-M-Q-M-L-G-G-R-S-D-G-G-G-M-G-G-G-G-E-R-P-Q-R-Q-T-S-Q-R-Q-D-Y-A-P-R-R-Q-A-R-Q-P-S-Q-S-P-Q-S-S-P-P-P-M-D-D-F-A-D-D-D-I-P-F"} +{"text": "### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-N-W-R-W-L-L-L-V-L-A-A-L-L-S-W-L-Q-H-R-F-W-F-G-P-G-N-S-G-E-V-R-M-L-Q-V-Q-I-V-Q-Q-H-Q-E-N-E-R-L-R-Q-R-N-A-S-L-A-A-E-V-K-N-L-K-D-G-D-A-A-I-E-E-R-A-R-S-E-L-G-M-I-K-P-G-E-I-F-Y-R-V-V-E-D-I-P-T-P-L-P-N-D-T-S-A-D-H-G-V-D-L-A-Q-P-R-R-E-K-R"} +{"text": "### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-S-E-L-P-V-V-E-S-D-R-R-L-I-W-I-D-L-E-M-T-G-L-D-T-H-R-D-S-I-I-E-I-A-T-V-V-T-D-A-Q-L-N-V-L-A-E-G-P-E-F-A-I-S-H-P-L-Q-M-L-E-A-M-D-E-W-N-R-N-Q-H-R-H-S-G-L-W-Q-R-V-L-N-S-E-I-Q-H-A-Q-A-E-A-S-T-I-A-F-L-Q-Q-W-V-K-T-G-A-S-P-M-C-G-N-S-I-C-Q-D-R-R-F-L-H-R-Q-M-P-C-L-E-R-Y-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-A-G-C-W-A-P-S-I-L-D-G-V-V-K-T-S-S-H-T-A-L-S-D-I-Y-D-S-I-A-E-L-R-H-Y-R-K-S-M-G-T-F-A-G-L-P-V-V"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-E-L-I-D-G-V-A-A-A-A-N-L-S-K-V-E-A-G-R-A-I-D-A-V-V-N-E-I-T-E-A-L-K-K-G-D-S-V-T-L-V-G-F-G-T-F-Q-V-R-P-R-A-E-R-P-G-R-N-P-K-S-G-E-L-I-M-I-A-A-S-N-N-P-S-F-K-P-G-K-A-L-K-D-A-V-K-C-S-A-G"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-Q-S-V-V-K-I-K-K-K-V-K-R-V-I-T-D-G-V-A-H-I-S-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-S-L-F-W-C-T-S-G-A-S-G-F-R-G-S-R-K-C-T-P-F-A-A-Q-V-A-A-E-K-A-G-R-A-V-L-D-Y-G-M-K-S-L-E-V-R-I-N-G-P-G-P-G-R-E-S-A-V-R-S-L-N-N-V-G-Y-K-I-T-N-I-I-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-L-A-I-Q-K-H-V-W-I-G-L-Q-S-I-Y-G-I-G-R-T-R-S-R-K-V-C-D-A-A-N-V-A-I-Y-T-K-I-R-D-L-S-E-P-E-I-E-R-L-R-V-E-V-G-K-Y-V-I-E-G-D-L-R-R-E-V-G-M-A-I-K-R-L-M-D-L-N-C-Y-R-G-L-R-H-R-R-G-L-P-L-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-K-A-I-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-I-M-S-L-R-L-N-D-L-K-P-A-L-G-A-S-S-C-R-A-R-V-G-R-G-I-G-S-G-L-G-K-T-A-G-R-G-H-K-G-S-F-A-R-K-G-G-G-K-I-K-P-G-F-E-G-G-Q-T-P-M-Q-R-R-L-P-K-I-G-F-R-S-R-S-V-A-N-T-A-E-V-L-S-Y-K-L-D-N-L-E-P-G-E-I-D-F-A-S-L-R-L-A-K-L-V-P-S-T-A-K-K-A-K-I-V-K-K-G-R-L-T-K-V-F-V-L-K-G-I-E-S-T-A-G-A-R-A-M-I-E-T-T-G-G-S-F-Q-E"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-E-E-R-S-Q-R-N-R-D-R-S-R-E-E-K-I-D-D-G-M-I-E-K-L-V-A-V-N-R-V-S-K-T-V-K-G-G-R-Q-F-T-F-T-A-L-T-I-V-G-N-G-E-G-S-V-G-F-G-Y-G-K-A-R-E-V-P-V-A-I-Q-K-S-M-E-Y-A-R-K-T-M-A-N-V-S-L-N-N-G-T-L-W-H-P-V-K-A-N-H-G-A-A-C-V-F-M-K-P-A-S-E-G-T-G-V-I-A-G-G-A-M-R-A-V-L-E-A-V-G-V-K-D-V-L-A-K-A-I-G-S-R-N-P-I-N-L-V-R-A-T-L-K-G-L-E-D-M-Q-S-P-T-H-I-A-L-K-R-G-K-N-V-R-G-F-S-H-G-S"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-I-G-K-N-V-A-R-L-R-R-A-K-S-T-R-V-H-I-R-K-L-G-V-P-R-L-S-V-L-R-T-G-R-H-L-Y-A-Q-I-F-T-A-D-G-S-K-V-I-A-A-A-N-T-L-Q-S-Q-V-K-D-G-L-K-N-G-K-N-S-L-A-A-T-K-V-G-K-L-I-A-E-R-A-K-A-V-G-V-D-R-I-A-F-D-R-S-G-Y-L-Y-H-G-R-I-K-I-L-A-D-A-A-R-D-A-G-L-K-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-K-P-I-S-V-P-K-G-V-E-V-S-V-R-S-D-M-L-T-V-K-G-V-K-G-V-L-T-F-P-K-S-D-N-V-N-V-V-V-D-G-D-I-L-T-L-S-A-N-D-P-S-H-V-S-L-A-G-T-V-R-A-I-L-S-N-M-I-K-G-V-S-I-G-F-E-R-K-L-E-L-V-G-V-G-Y-R-A-S-M-Q-G-E-N-L-N-L-S-L-G-F-S-H-P-L-V-F-V-P-P-E-G-I-T-L-L-T-P-S-Q-T-E-V-V-V-Q-G-I-D-K-Q-R-V-G-E-V-A-A-K-I-R-S-F-R-P-P-E-P-Y-K-G-K-G-L-K-Y-A-A-E-A-I-M-R-K-E-A-K-K-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-T-D-P-I-A-D-M-L-V-R-I-N-N-A-A-S-V-G-K-P-N-V-R-F-P-F-S-R-V-K-L-A-I-A-L-V-L-K-H-E-G-Y-I-F-D-A-K-V-I-Q-G-D-N-S-K-S-D-I-E-I-V-L-K-Y-F-E-G-R-P-V-I-R-I-L-K-R-V-S-R-S-G-L-R-K-Y-C-G-K-A-E-L-P-K-V-L-G-G-L-G-I-S-I-I-S-T-S-K-G-I-M-I-D-S-K-A-R-E-S-G-V-G-G-E-V-L-C-F-V-A"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-I-S-M-I-N-R-D-L-K-R-K-R-L-A-K-K-F-A-D-K-R-L-S-L-K-K-V-I-S-S-D-A-S-S-Y-E-E-K-I-E-A-S-C-K-L-Q-K-L-P-R-D-S-S-P-T-R-L-R-N-R-C-E-I-S-G-R-P-R-G-V-Y-C-K-F-G-L-G-R-N-K-L-R-E-A-A-M-R-G-D-V-P-G-L-R-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-R-L-E-N-M-Y-K-K-E-V-V-P-A-L-I-K-R-F-G-Y-S-N-P-M-A-V-P-R-L-V-K-I-T-L-N-M-G-V-G-E-A-A-T-N-K-K-V-L-E-N-A-V-A-D-M-A-K-I-S-G-Q-R-P-I-V-T-K-S-R-I-S-V-A-S-F-K-I-R-N-G-W-P-I-G-C-K-T-T-L-R-R-S-K-M-Y-E-F-L-D-R-L-I-N-I-S-L-P-C-V-R-D-F-R-G-I-P-P-R-S-F-D-G-R-G-N-F-N-M-G-V-K-E-Q-V-V-F-P-E-I-D-F-D-A-V-D-A-I-R-G-M-D-I-A-I-T-T-T-A-N-S-D-A-E-A-K-A-L-L-D-A-F-N-F-P-F-R-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-S-R-I-K-K-G-D-Q-V-I-V-I-A-G-K-D-K-G-K-Q-G-E-I-I-R-I-D-G-H-R-V-V-V-S-N-V-N-I-V-K-R-H-T-K-P-N-P-Q-R-S-I-S-G-G-L-I-D-R-E-A-P-I-H-V-S-N-I-Q-V-L-N-P-M-T-G-K-G-D-R-V-G-F-K-I-L-D-D-G-C-K-L-R-I-F-R-S-T-G-E-V-I-G-A"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-Y-L-G-V-A-D-N-S-G-A-K-E-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-S-I-G-D-I-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-E-V-Y-D-A-V-V-V-R-T-R-S-G-V-R-R-P-D-G-S-L-I-R-F-D-G-N-A-A-V-L-L-N-N-K-Q-E-P-I-G-T-R-V-F-G-P-V-T-R-E-L-R-S-E-K-L-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-M-N-D-H-N-E-R-K-P-L-R-T-I-K-G-R-V-I-S-N-K-M-Q-K-T-V-T-V-L-V-E-R-Q-I-K-H-A-L-Y-G-K-Y-I-K-R-S-T-K-L-H-A-H-D-A-D-D-L-C-N-E-G-D-V-V-L-M-T-E-V-A-P-I-S-K-T-K-N-W-R-V-V-E-I-V-A-R-S-D"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-Y-R-K-M-H-K-G-R-N-C-G-L-S-W-N-A-N-V-V-S-F-G-Q-Y-G-L-R-A-T-A-H-G-Q-L-T-A-R-Q-I-E-A-A-R-R-S-I-S-R-Y-V-K-R-G-G-K-L-L-I-R-V-F-P-D-K-P-I-T-K-K-P-I-E-V-R-M-G-S-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-R-M-I-Y-E-I-E-G-V-S-E-D-V-A-R-E-A-F-R-L-A-A-S-K-L-S-V-T-T-A-F-V-V-R-T-V-R"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-T-A-I-L-R-G-A-R-I-S-P-Q-K-A-R-L-V-A-A-Q-V-R-G-L-S-A-E-S-A-V-N-I-L-R-F-S-S-K-K-A-A-C-L-I-K-K-V-V-E-S-A-I-A-N-A-E-N-N-H-G-S-N-I-D-A-L-K-I-N-T-I-I-V-D-E-G-R-M-L-K-R-F-M-A-R-A-K-G-R-S-S-R-I-V-K-R-S-S-H-I-T-V-V-V-G-P-A-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-T-K-K-G-P-F-F-D-H-H-L-I-K-K-V-E-S-A-A-G-S-K-R-P-I-K-T-C-S-R-R-S-V-I-L-P-Q-M-V-G-H-T-I-A-I-H-N-G-K-N-Y-Y-P-V-V-I-N-E-N-M-V-G-H-K-L-G-E-F-S-I-T-R-V-F-K-G-H-G-G-D-K-K-S-G-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-S-S-C-E-K-I-F-G-V-L-R-S-P-R-V-S-E-K-S-S-R-L-Q-E-I-S-N-V-Y-V-F-E-V-S-S-D-A-T-K-V-D-V-K-N-A-V-E-R-L-F-D-V-K-V-G-V-V-R-V-L-N-V-K-G-K-S-K-S-F-R-N-R-G-G-S-R-S-G-W-R-K-A-Y-V-R-L-I-D-G-Q-S-I-D-V-A-A-N-V"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-I-T-F-T-I-F-A-Q-S-L-A-F-A-A-L-I-W-I-V-A-T-K-I-W-P-P-L-I-K-V-I-E-E-R-Q-Q-K-I-A-E-G-L-A-A-A-D-L-G-Q-K-E-L-A-Q-A-Q-E-E-I-K-K-T-L-K-N-A-R-E-K-A-N-E-I-I-E-Q-A-H-A-R-A-H-Q-I-I-E-A-A-K-A-E-A-I-T-E-T-N-R-Q-Q-N-L-A-Q-V-E-I-E-A-A-A-K-R-A-R-E-E-L-R-K-H-V-S-I-L-A-V-N-G-A-E-K-L-L-K-R-E-I-D-V-N-T-H-K-M-L-L-D-E-L-A-A-E-I"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-Q-A-L-T-L-A-R-P-Y-A-R-A-A-F-A-I-A-C-E-K-G-K-C-M-Q-W-S-Q-A-L-T-F-S-A-Q-V-A-N-N-P-I-A-A-A-L-L-C-H-P-Q-I-D-H-E-Q-A-A-A-L-L-S-P-E-G-A-D-P-A-Y-V-R-F-L-E-V-I-A-E-A-H-R-L-D-V-L-L-Q-V-A-G-L-Y-E-K-L-R-A-E-A-E-H-V-I-K-A-K-I-T-S-A-I-E-L-A-P-N-E-L-N-N-I-V-T-A-L-K-K-R-F-D-C-E-I-E-V-T-T-G-V-D-H-S-L-I-G-G-A-V-I-D-T-G-N-V-V-I-D-G-S-I-K-S-K-L-T-R-L-Q-A-S-L-T-H"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-L-Y-L-A-S-R-S-L-C-R-R-Q-L-L-Q-R-L-D-I-P-F-Q-V-I-D-L-E-I-P-E-V-R-R-E-D-E-L-P-Q-D-Y-V-R-R-V-A-Q-E-K-A-Q-V-G-L-A-R-V-R-D-A-F-A-P-K-V-L-G-A-D-T-E-V-V-L-D-G-R-V-F-G-K-P-A-D-L-V-E-A-A-A-M-L-A-A-L-S-G-R-T-H-Q-V-M-T-A-V-S-L-V-A-A-G-G-V-A-A-Q-V-L-V-V-S-E-V-S-F-A-L-L-S-Q-G-Q-I-A-R-Y-V-D-S-G-E-P-M-G-K-A-G-A-Y-A-I-Q-G-R-G-E-C-F-V-S-R-L-V-G-S-Y-S-G-V-M-G-L-P-L-Q-Q-T-A-Q-L-L-T-T-F-E-E-S"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-R-A-P-M-T-L-K-G-V-R-R-L-R-D-E-L-E-H-L-K-S-V-K-R-P-E-I-I-N-A-I-A-E-A-R-A-H-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-Q-Q-S-F-I-E-G-R-I-K-Q-L-E-G-E-L-S-H-A-E-V-I-D-V-A-K-L-N-A-G-T-K-I-V-F-G-A-T-V-T-L-V-D-L-E-T-D-E-E-S-R-Y-Q-I-V-G-D-L-E-A-D-I-K-Q-G-L-V-A-I-S-S-P-V-A-R-A-L-I-G-K-Q-E-G-D-T-I-V-I-E-A-P-A-G-R-R-E-Y-E-V-V-A-V-E-Y-I-S"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-N-Q-I-K-Q-D-A-Q-D-R-M-T-K-S-I-D-A-L-R-N-S-L-A-S-V-R-T-G-R-A-S-P-S-L-L-D-G-I-K-I-K-A-Y-G-T-D-T-P-L-N-Q-V-A-S-I-S-V-S-E-G-R-S-L-V-I-T-V-F-D-K-N-M-S-K-D-V-E-K-A-I-Y-A-S-D-L-G-L-T-P-T-V-V-G-T-L-I-R-L-N-L-P-P-L-T-E-E-R-R-K-E-L-T-K-V-V-H-S-E-G-E-D-T-K-V-A-I-R-N-I-R-R-D-A-N-Q-Q-I-K-D-M-L-K-S-K-E-I-T-E-D-E-V-R-Q-G-E-E-D-I-Q-K-L-T-D-K-A-I-K-S-V-D-E-V-V-K-S-K-E-Q-E-L-M-T-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-H-K-A-I-M-H-P-L-I-L-L-L-K-I-Y-K-R-L-I-S-P-L-L-G-P-H-C-R-F-E-P-S-C-S-E-Y-A-M-G-A-I-A-R-F-G-T-L-R-G-I-W-L-A-A-R-R-L-A-R-C-Q-P-L-Q-P-G-G-Y-D-P-V-P-D-N-I-S-T-Q-V-N-P-P-S-H-R-C-T-G-H-H-Q"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-N-A-S-G-G-G-P-R-P-R-R-R-D-G-V-D-P-A-L-R-S-R-A-R-R-R-A-L-Q-A-V-Y-A-W-Q-I-S-G-G-V-A-K-Q-V-I-A-H-F-A-H-E-Q-A-Y-E-V-A-D-L-A-Y-F-E-D-L-V-E-G-V-L-T-H-C-A-E-L-D-E-K-L-T-P-Y-L-D-R-T-I-E-E-V-D-A-I-E-R-A-V-L-R-L-G-A-Y-E-L-L-Y-R-Q-D-V-P-Y-R-V-V-I-N-E-A-I-M-T-A-K-R-F-G-S-K-Y-G-H-T-Y-V-N-G-V-L-D-R-A-A-L-A-L-R-K-V-E-V-L-G"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Y-C-L-F-C-Q-H-T-Y-T-R-V-I-D-S-R-V-S-E-D-G-A-T-I-R-R-R-R-E-C-E-A-C-G-E-R-F-S-T-L-E-T-I-E-L-K-L-P-V-I-I-K-K-D-G-G-R-E-A-F-D-G-R-K-L-R-T-S-F-D-R-A-L-Q-K-R-P-V-A-E-E-C-I-E-M-A-L-R-A-V-I-H-R-L-R-M-A-G-E-R-E-V-P-S-I-V-V-G-E-Y-V-M-A-E-L-R-K-L-D-H-V-G-Y-V-R-F-A-S-V-Y-R-S-F-Q-D-V-A-D-F-R-E-E-I-E-K-L-E-S-E-L-L-V-S-R-E-Q-L-P-L-L-E-A-A-M-E-S-M-G-H-P-S-V-D-Q-G-G-K-H-G-V"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-R-G-P-I-F-L-N-V-G-I-S-Y-G-L-P-R-T-K-L-P-A-A-V-S-F-R-K-W-V-A-A-T-L-Q-G-R-I-R-K-A-D-L-A-I-R-I-V-D-E-K-E-G-R-A-L-N-Y-H-Y-R-N-K-D-Y-A-T-N-V-L-S-F-P-A-Q-L-P-E-P-L-P-K-A-L-K-I-P-L-L-G-D-I-V-M-C-A-P-V-I-A-R-E-A-A-E-Q-G-K-S-L-S-A-H-Y-A-H-L-T-V-H-G-T-L-H-L-L-G-W-N-H-E-D-H-Q-E-A-D-A-M-E-Q-L-E-R-E-I-L-A-N-L-G-I-S-D-P-Y-L-E-E-Y"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-E-M-V-E-R-L-F-D-E-V-G-L-N-K-R-E-A-K-E-F-V-D-T-F-F-D-L-L-R-D-A-L-E-Q-G-R-Q-I-K-L-S-G-F-G-N-F-E-L-R-C-K-N-Q-R-P-G-R-N-P-K-T-G-E-E-I-P-I-S-A-R-T-V-V-T-F-R-S-G-Q-K-L-K-E-R-V-D-A-Y-V-G-S-R-Q"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-Q-A-R-R-R-H-K-K-I-L-S-L-A-K-G-Y-Y-N-A-R-R-K-V-F-R-V-A-K-Q-A-V-I-K-A-Q-Q-Y-A-Y-I-G-R-K-Q-K-K-R-N-F-R-S-L-W-I-V-R-I-N-A-A-A-R-I-N-G-L-S-Y-S-R-F-M-N-G-L-L-K-C-G-I-T-L-D-R-K-V-L-A-D-I-A-V-H-D-P-A-G-F-T-A-L-A-E-K-A-K-S-I-L-A-A"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-G-D-C-N-I-S-T-S-D-N-K-Q-N-R-K-N-H-E-I-R-V-P-R-V-R-V-I-G-S-D-G-E-M-V-G-V-L-S-R-D-E-A-L-A-M-A-E-K-E-G-L-D-L-V-E-I-Q-P-Q-A-D-P-P-V-C-K-V-M-N-F-G-K-F-K-F-E-Q-Q-K-K-A-N-E-A-K-K-K-T-K-Q-V-E-I-K-E-L-K-F-R-P-V-T-D-E-G-D-Y-Q-I-K-L-R-N-M-R-R-F-L-E-E-G-D-K-V-K-I-N-I-R-F-R-G-R-E-M-S-H-Q-E-L-G-R-Q-M-A-T-R-I-E-M-D-L-G-D-D-V-V-I-E-S-R-P-R-L-E-G-R-Q-M-V-M-M-V-A-P-R-K-K-S"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-P-K-H-S-P-P-D-T-S-P-V-A-R-F-E-Q-S-L-Q-E-L-E-Q-L-V-Q-N-M-E-T-G-A-L-S-L-E-Q-S-L-G-A-Y-E-R-G-I-A-L-Y-R-E-C-H-Q-A-L-E-Q-A-Q-L-R-V-R-L-L-S-D-P-M-H-P-D-D-G-E-P-F-D-P-S-L-V-S-T-S-Q"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-L-L-H-W-L-V-V-L-V-I-V-L-L-V-F-G-T-K-R-L-A-N-G-A-K-D-I-G-S-A-I-K-E-F-K-K-S-L-R-E-D-D-K-P-T-D-Q-L-G-S-T-S-Q-S-T-A-S-G-P-Q-Q-D-H-G-K-H"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-S-E-L-L-L-I-A-V-V-A-L-V-V-L-G-P-E-R-L-P-K-A-A-R-F-A-G-L-L-V-R-R-A-R-T-Q-W-E-S-I-K-Q-E-L-E-R-E-L-E-A-E-A-L-K-R-N-L-E-N-A-Q-Q-V-I-H-D-A-Q-A-Q-L-Q-S-N-Q-Q-D-M-N-I-Q-N-S-I-S-I-L-H-E-Q-T-K-R-D-I-H-P-D-R-N-T-N-T-L-E-L-G-T-A-V-H-H-V-H-V-T-S-P-P-P-S-T-S-T-H-G-N-N-G-Q-E-K-S-Q"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-P-D-G-Y-R-P-N-V-G-I-V-L-M-C-R-D-G-Q-V-F-W-G-R-R-V-R-L-D-G-W-Q-F-P-Q-G-G-M-H-S-D-E-T-P-V-E-A-M-Y-R-E-L-N-E-E-T-G-L-L-P-E-H-V-Q-L-L-G-A-T-P-G-W-L-R-Y-R-L-P-S-Q-A-V-R-C-N-R-S-Q-M-C-I-G-Q-K-Q-V-W-F-L-L-Q-L-I-G-D-E-S-H-V-Q-L-D-Q-S-E-N-P-E-F-D-H-W-R-W-V-S-F-W-Y-P-I-E-H-V-V-M-F-K-R-G-V-Y-A-R-A-L-C-Q-L-A-S-L-A-Q-Q-V-V-G-L-E-V-G-T-M-P-Q-Y-V-Q-D-I-C-L-L-N-V-G-Y-K-H-L-P-N-W-V-S-R-Y"} +{"text": "### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-N-A-L-Q-W-S-F-R-A-Q-C-L-T-G-F-L-F-C-T-G-L-L-A-Y-A-I-F-L-Q-L-H-Q-G-L-E-P-C-P-L-C-I-F-Q-R-I-A-F-A-V-L-G-I-L-F-L-I-A-G-L-Y-N-S-S-N-V-Y-T-R-K-A-Y-G-L-L-I-F-L-T-A-A-I-G-T-G-I-A-G-R-H-V-W-V-Q-L-M-P-H-N-T-I-S-S-C-G-S-P-L-S-F-L-S-E-T-M-G-P-F-E-V-F-R-T-V-L-T-G-T-S-D-C-G-N-I-D-W-R-F-L-G-L-S-M-P-M-W-S-M-F-W-F-V-A-L-A-L-L-G-L-L-V-G-F-K-A-E-R-R-K-P-L-F-S"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-M-K-C-L-L-I-A-T-G-E-R-V-P-T-W-V-A-Q-G-F-A-E-Y-H-K-R-L-S-Y-W-L-P-L-E-L-V-E-I-E-P-S-L-R-G-K-N-H-D-P-Q-Q-A-I-E-D-E-G-R-R-V-M-A-A-L-P-K-Q-P-Y-A-V-T-L-D-V-K-G-K-S-L-N-S-E-Q-L-A-K-R-M-E-H-W-R-G-L-G-R-N-L-V-F-L-I-G-G-P-E-G-H-S-Q-E-V-L-N-I-S-N-E-R-W-S-L-G-P-L-T-L-P-H-M-L-V-R-L-I-V-V-E-Q-L-Y-R-A-A-T-I-L-T-N-H-P-Y-H-R-G-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-K-K-S-F-Q-R-A-E-R-I-S-V-Q-I-H-R-D-L-G-A-L-V-Q-A-A-V-R-D-H-G-L-P-S-M-S-V-S-D-V-E-V-T-R-D-M-A-H-A-K-V-F-V-T-A-L-Q-A-E-R-S-F-E-A-V-A-G-L-K-A-L-A-R-E-L-R-M-Q-L-A-H-T-M-R-L-R-F-V-P-E-L-H-F-H-Y-D-D-S-L-D-R-G-E-R-I-N-T-L-L-R-D-L-I-P-P-A-D-A-E-K-D-E-C-G"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-D-K-G-I-E-I-V-N-L-L-A-P-K-V-E-T-L-G-F-E-L-L-G-A-E-Y-L-L-V-P-S-G-A-I-L-R-L-Y-I-D-T-P-F-A-M-Q-P-E-C-M-V-S-I-D-D-C-E-R-V-S-R-E-V-S-A-Y-L-D-V-E-E-P-I-S-G-N-Y-T-L-E-V-S-S-P-G-L-D-R-R-L-F-T-L-E-Q-F-A-R-H-Y-N-Q-F-V-K-V-G-L-K-L-P-Q-H-G-S-R-R-L-Q-G-K-I-V-R-V-E-Q-V-D-G-F-V-V-L-L-V-N-G-V-E-L-A-V-D-F-N-N-I-D-K-A-R-I-V-P-D-W-S-A-L-G-L-A-P-L-E-K-S-K-P-D-T-K-K-T-S-Q-G-N-K-K-P-S-N-E-S-A-A-R-Q-A-V-R-G-V-I-R"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-D-I-P-G-D-L-K-F-L-K-S-H-E-W-V-R-I-E-D-N-N-R-A-I-V-G-I-S-D-H-A-Q-N-L-L-G-D-L-V-Y-V-E-L-P-N-I-G-D-H-L-D-A-G-T-T-A-A-V-I-E-S-V-K-A-A-S-D-I-Y-S-P-V-T-G-K-V-I-E-V-N-T-T-L-S-D-K-P-E-T-I-N-E-D-P-Y-G-E-G-W-I-M-V-I-E-M-Q-A-P-E-E-I-S-D-L-L-S-P-D-D-Y-T-K-V-L-E-S-D-E-H"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-S-A-A-V-Q-P-L-Q-I-K-I-L-D-P-R-L-G-T-V-W-L-L-P-T-Y-A-T-E-A-S-A-G-L-D-L-R-A-A-L-D-A-P-M-T-L-V-P-G-D-A-E-L-L-S-T-G-V-A-I-H-L-V-D-P-S-L-C-A-V-V-L-P-R-S-G-L-G-H-R-H-G-I-V-L-G-N-G-T-G-L-I-D-S-D-Y-Q-G-P-L-L-V-S-V-W-N-R-G-R-E-A-F-T-I-E-P-G-D-R-I-A-Q-L-V-V-L-P-I-V-R-V-V-L-Q-V-V-D-T-F-V-E-S-G-R-G-A-G-G-F-G-H-T-G-V-R"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-K-L-N-K-S-I-I-A-E-F-E-S-A-Q-I-T-R-Q-V-P-Q-F-S-Q-G-D-T-I-V-V-N-V-K-V-K-E-G-N-R-E-R-L-Q-A-Y-E-G-V-V-I-A-T-K-N-A-G-L-N-S-A-F-T-V-R-K-I-S-H-G-Y-G-V-E-R-V-F-Q-T-H-S-P-I-I-E-S-I-E-I-K-R-R-G-K-V-R-A-A-K-L-Y-Y-L-R-G-L-E-G-K-A-A-R-I-K-E-D-L-A-A-T-A-Q-E-K-L-A-R-K-T-V-T-A-K-A-G"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-D-N-E-R-R-I-L-L-G-R-V-V-G-G-F-G-L-R-G-E-I-K-I-E-S-W-T-E-P-R-D-A-I-F-R-Y-Q-P-W-L-L-R-S-P-T-G-T-E-S-M-L-N-G-A-R-G-Y-E-T-G-K-R-L-I-A-T-F-P-G-I-N-D-R-N-A-V-E-A-I-C-G-T-E-I-Y-V-P-R-S-A-L-P-P-P-H-P-D-E-Y-Y-W-V-D-L-E-G-L-Q-V-H-T-L-E-G-V-V-L-G-S-V-S-H-L-F-S-N-G-A-N-D-V-I-V-I-H-G-E-R-E-R-L-I-P-F-V-Q-P-D-Y-V-K-S-V-D-F-E-A-E-R-I-V-V-D-W-D-P-E-F"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-T-I-E-S-F-D-Q-F-V-V-L-L-R-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-N-V-R-V-G-P-G-G-G-Y-V-Q-S-G-S-D-T-L-Q-I-N-D-D-E-V-E"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-F-I-R-E-F-K-E-F-V-M-R-G-N-V-I-D-L-A-V-A-V-V-I-G-A-A-F-G-K-I-V-T-A-L-V-D-K-I-I-S-P-L-I-G-V-M-V-G-G-I-D-F-S-K-L-S-L-T-L-K-A-A-T-V-D-A-A-G-K-E-V-P-A-V-V-I-G-Y-G-D-F-L-N-T-I-L-Q-F-I-I-I-A-F-A-I-F-I-I-V-K-M-I-N-K-V-I-N-K-Q-P-L-P-P-E-T-P-S-E-D-V-L-L-L-R-E-I-R-D-S-L-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-L-L-I-K-D-V-K-A-L-G-K-A-G-E-I-K-E-V-K-D-G-Y-G-Q-N-F-L-I-A-K-G-F-A-K-A-A-T-N-E-V-L-R-K-Y-E-S-D-K-K-K-E-A-E-N-L-R-F-E-I-A-N-L-E-K-L-K-E-E-L-S-K-I-T-L-E-I-S-K-P-V-G-A-N-G-S-L-F-G-G-V-T-K-D-E-I-A-H-A-L-K-E-Q-S-H-I-E-I-D-K-K-S-L-E-C-D-T-L-K-S-L-G-I-H-E-V-S-V-K-L-G-H-A-I-H-A-K-F-N-I-N-I-K-A-E"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-I-I-S-A-K-F-I-T-S-L-V-K-F-D-E-N-L-S-S-N-F-S-E-V-A-F-L-G-R-S-N-V-G-K-S-S-L-I-N-S-L-C-K-Q-K-N-L-A-K-S-S-A-T-P-G-K-T-Q-L-I-N-F-F-E-V-I-C-R-R-N-E-E-K-F-N-I-N-F-I-D-L-P-G-F-G-Y-A-K-V-S-K-N-L-K-E-I-W-N-Q-N-L-D-E-F-L-K-L-R-T-S-I-K-L-F-I-H-L-I-D-S-R-H-T-H-L-E-I-D-V-N-L-N-D-Y-L-K-R-F-L-R-P-D-Q-K-I-L-K-V-F-T-K-C-D-K-L-N-Q-S-E-K-A-K-L-K-N-E-F-K-D-S-I-L-V-S-N-L-N-K-F-G-L-D-S-L-E-D-I-I-I-N-Q-T-L-G-L-D-K"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-K-N-I-V-L-G-G-G-C-F-W-C-V-E-A-V-F-E-R-L-K-G-V-I-N-T-E-V-G-Y-S-G-G-K-P-N-P-S-Y-E-S-V-C-N-G-D-G-N-I-E-V-V-K-I-N-Y-D-E-K-Q-I-S-L-L-E-I-L-T-L-F-F-K-I-H-D-P-T-S-I-D-K-Q-G-G-D-I-G-I-Q-Y-R-S-I-I-F-Y-E-N-E-E-D-K-I-L-A-Q-N-F-I-E-E-Q-Q-K-I-F-S-K-K-I-V-T-K-I-S-R-L-Q-T-Y-Y-K-A-E-N-Y-H-Q-H-Y-F-I-N-N-P-D-Q-G-Y-C-Q-A-V-I-A-P-K-L-Q-K-I-Q-S-D"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-A-L-A-L-D-V-G-L-K-R-I-G-V-A-L-C-I-D-K-K-I-A-L-P-L-D-A-V-L-R-K-N-R-N-Q-A-A-N-E-I-K-N-L-L-K-I-H-E-I-S-L-L-I-V-G-I-P-K-G-G-S-S-E-E-E-M-T-R-R-I-K-H-F-V-S-L-L-E-F-D-K-E-I-C-F-V-D-E-S-G-T-S-K-E-A-L-G-Y-G-V-A-N-T-R-K-K-D-G-K-L-D-S-L-S-A-F-I-M-I-K-D-Y-F-A-L"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-I-V-E-S-L-I-E-L-C-E-E-N-A-L-N-N-K-A-Y-N-V-Q-E-I-Y-V-K-I-G-R-L-S-G-I-E-V-D-L-F-K-R-C-F-E-T-F-K-E-N-S-N-I-C-K-N-A-K-L-F-I-E-L-A-P-L-E-I-L-C-L-K-C-D-Q-T-S-I-L-E-E-N-V-F-K-C-P-K-C-Q-S-I-E-Y-K-I-I-Q-G-E-D-L-H-L-M-R-L-V-M-K"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-E-N-E-K-N-Y-R-P-N-V-A-A-I-V-L-S-S-S-Y-P-F-E-C-K-I-F-I-A-R-R-S-D-M-D-N-I-W-Q-F-P-Q-G-G-I-D-K-G-E-S-V-K-N-A-L-F-R-E-L-K-E-E-I-G-T-D-E-V-E-I-I-A-E-Y-P-E-W-L-S-Y-D-F-P-S-K-I-V-K-K-M-Y-P-Y-D-G-Q-I-Q-K-Y-F-L-V-R-L-K-H-G-A-T-I-N-I-N-T-K-H-P-E-F-D-D-Y-Q-F-V-S-V-K-Q-I-F-E-M-I-N-H-F-K-K-N-I-Y-V-R-V-I-K-Y-F-E-E-K-G-Y-I"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-S-F-G-E-I-I-V-I-L-V-V-A-I-L-V-L-G-P-D-K-L-P-E-A-I-V-Q-I-A-K-I-L-K-A-V-K-R-N-I-D-D-A-K-S-S-I-E-K-E-I-R-I-N-D-L-K-E-E-A-K-K-Y-K-D-E-F-S-S-T-N-E-N-I-R-K-K-L-S-F-E-E-F-D-D-L-K-R-D-I-L-D-K-T-K-V-D-L-T-F-D-S-R-D-D-K-V-K-N-N-L-S-G-Q-N-L-N-T-E-E-K-P-N-L-S-K-L-E-T-Q-D-K-N-G-K-I-N-V"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-Y-S-M-G-D-L-K-K-G-L-K-I-E-I-D-G-I-P-F-K-I-V-E-Y-Q-H-V-K-P-G-K-G-P-A-F-V-R-I-K-I-K-S-F-I-D-G-K-V-L-E-K-T-F-H-A-G-D-K-C-E-A-P-N-L-E-D-K-T-M-Q-Y-L-Y-D-D-G-E-N-C-Q-F-M-D-T-Q-T-Y-E-Q-V-A-I-S-D-D-D-V-G-E-A-K-K-W-M-L-D-G-M-M-V-D-V-L-F-H-N-G-K-A-I-G-V-E-V-P-Q-V-V-E-L-K-I-I-E-T-A-P-N-F-K-G-D-T-Q-G-S-N-K-K-P-A-T-L-E-T-G-A-V-V-Q-I-P-F-H-V-L-E-G-E-V-I-R-V-D-T-V-R-G-E-Y-I-E-R-A-N-K"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-N-T-L-L-V-V-G-F-G-G-F-I-G-A-I-L-R-M-L-S-I-N-L-V-N-K-F-F-P-Y-S-I-S-F-G-T-L-F-V-N-V-L-G-S-F-I-I-G-L-L-F-S-Y-A-Q-N-K-G-L-S-P-L-L-K-S-F-I-S-T-G-F-L-G-A-F-T-T-F-S-T-F-S-Y-Q-N-L-L-L-L-Q-S-G-N-Y-L-H-F-A-L-N-I-I-L-N-V-F-L-C-L-F-A-A-W-L-G-F-L-I-F-K"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-L-I-L-A-S-S-S-I-S-R-A-N-L-L-K-T-A-K-I-D-F-R-Q-V-S-F-D-Y-D-E-N-L-N-K-N-I-S-P-F-L-Y-V-Q-K-I-V-L-E-K-E-R-Q-F-L-S-T-L-G-K-D-F-Q-N-Q-N-L-L-F-A-D-S-I-V-C-I-D-E-K-I-L-T-K-A-K-D-K-K-E-A-Y-E-M-L-A-L-Q-N-G-K-Y-A-S-I-L-S-A-F-L-L-V-K-P-E-K-R-V-F-S-L-S-K-T-T-L-Y-F-K-N-F-D-E-N-A-L-R-D-Y-V-E-N-D-L-Y-K-G-K-A-G-C-I-M-C-E-G-F-H-Q-N-F-I-T-Q-Q-V-G-N-L-S-T-A-L-G-L-D-I-Q-T-L-K-A-Y-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-R-R-K-A-P-V-R-E-V-L-P-D-P-I-Y-G-N-K-V-I-T-K-F-I-N-S-L-M-Y-D-G-K-K-S-T-A-T-T-I-M-Y-G-A-L-E-A-I-D-K-K-G-G-E-K-K-G-I-D-I-F-N-D-A-I-E-N-I-K-P-L-L-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-P-A-R-Q-Q-A-L-A-I-R-W-I-I-S-F-A-R-K-R-S-E-R-T-M-I-D-K-L-A-A-E-L-L-D-A-A-N-S-K-G-A-S-F-K-K-K-E-D-T-Y-K-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-K-E-R-K-K-V-L-E-K-S-K-S-P-A-L-K-N-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-V-R-L-T-S-G-F-E-V-I-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-I-V-L-V-R-G-G-R-V-K-D-L-P-G-V-K-Y-H-I-V-R-G-A-L-D-T-A-G-V-A-K-R-T-V-S-R-S-K-Y-G-A-K-R-P-K-A-G-A-A-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-I-S-K-E-D-V-L-E-Y-I-S-N-L-S-V-L-E-L-S-E-L-V-K-E-F-E-E-K-F-G-V-S-A-A-P-V-M-V-A-G-G-A-V-A-G-G-A-V-A-A-A-E-E-K-T-E-F-D-I-V-L-T-D-G-G-A-K-K-I-E-V-I-K-I-V-R-A-L-T-G-L-G-L-K-E-A-K-D-A-V-E-Q-T-P-S-T-L-K-E-G-V-A-K-A-E-A-E-E-A-K-K-Q-L-E-E-A-G-A-K-V-E-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-T-R-S-E-K-V-E-I-I-A-K-L-E-E-G-F-K-A-S-E-A-I-V-V-C-N-Y-R-G-L-S-T-K-K-L-E-E-L-R-N-N-A-R-E-N-N-V-K-V-Q-I-V-K-N-T-L-A-N-I-A-L-N-N-S-G-K-T-G-L-V-L-K-D-T-N-I-Y-L-W-G-E-D-Q-L-S-V-S-K-V-A-A-K-F-E-E-N-N-D-K-F-E-I-K-T-A-H-I-E-G-E-V-A-D-V-A-K-V-K-A-L-A-K-M-P-S-R-N-E-L-L-A-M-L-L-Q-V-W-N-A-P-I-T-N-F-T-I-G-L-N-A-L-K-N-K-K-E-S-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-V-G-E-I-K-L-Q-I-A-A-T-K-A-N-P-S-P-P-V-G-P-A-L-G-Q-Q-G-V-N-I-M-E-F-C-K-A-F-N-E-R-T-K-D-M-A-G-F-N-I-P-V-V-I-T-V-Y-A-D-K-S-F-T-F-I-T-K-Q-P-P-A-T-D-L-I-K-K-A-A-G-I-S-K-G-T-D-N-P-L-K-N-K-V-G-K-L-T-R-A-Q-V-L-E-I-V-D-K-K-I-A-D-L-N-T-K-D-R-D-Q-A-A-K-I-I-A-G-S-A-R-S-M-G-V-E-I-V-D"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-S-T-H-K-W-Y-A-I-Q-T-Y-A-G-S-E-M-A-V-K-R-A-I-E-N-L-V-K-D-N-G-I-E-E-Q-L-K-E-I-V-V-P-T-E-D-V-I-E-F-K-N-G-K-E-K-I-S-E-R-S-L-Y-S-G-Y-V-F-A-L-L-D-L-N-T-E-L-W-H-R-I-Q-S-L-P-K-V-G-R-F-I-G-E-S-K-K-P-T-P-L-T-E-K-D-I-N-L-I-L-E-K-V-H-N-R-A-A-P-K-P-K-I-S-F-E-E-G-E-N-V-R-I-T-E-G-P-F-A-N-F-T-A-I-V-E-E-Y-D-M-V-R-G-L-L-K-L-N-V-S-I-F-G-R-S-T-P-V-E-I-L-Y-S-Q-V-E-K-I-I"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-T-F-D-D-V-K-A-V-V-V-E-Q-L-S-I-D-A-D-A-V-K-M-E-S-K-I-I-E-D-L-G-A-D-S-L-D-V-V-E-L-I-M-A-L-E-E-K-F-E-V-E-I-P-D-S-D-A-E-K-L-I-K-I-E-D-V-V-N-Y-I-D-N-L-K-K"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-Q-I-D-E-K-L-L-S-K-L-E-K-L-S-A-L-Q-I-T-K-N-R-N-E-T-I-A-Q-L-S-E-I-V-N-F-V-E-K-L-N-E-L-D-L-D-S-Q-E-I-T-V-S-T-I-K-G-G-A-P-L-R-I-D-E-I-R-N-S-N-V-I-D-E-V-L-D-C-A-P-K-K-Q-E-H-F-F-V-V-P-K-I-I-E"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-N-I-I-E-G-K-L-N-L-D-S-N-T-K-I-A-I-I-N-A-R-F-N-H-I-I-T-D-R-L-V-E-G-A-K-D-A-F-L-R-H-G-G-K-E-E-N-L-S-L-I-L-V-P-G-A-F-E-L-P-Y-A-L-K-K-A-I-E-S-K-K-F-D-A-I-C-C-V-G-A-V-I-R-G-S-T-P-H-F-D-Y-V-S-A-E-T-T-K-G-I-A-N-V-S-L-N-H-N-I-P-V-S-F-G-V-L-T-T-D-T-I-E-Q-A-I-E-R-A-G-S-K-A-G-N-K-G-F-E-A-M-T-T-V-I-E-M-L-N-L-S-K-E-L"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-A-T-R-H-Q-V-R-Q-S-V-I-S-L-L-Y-A-F-E-L-N-S-Q-N-N-V-F-V-D-E-I-L-D-E-K-K-I-R-N-E-Q-K-N-F-T-L-N-L-Y-N-G-I-L-D-N-L-N-N-I-D-E-T-L-N-S-F-L-N-D-N-Q-I-T-A-L-G-H-V-E-R-A-I-L-R-L-G-A-Y-E-L-L-F-T-D-T-P-S-A-I-V-I-N-E-A-I-E-L-A-K-E-L-A-N-D-N-S-P-K-F-I-N-G-V-L-D-A-L-I-K-A-K-K"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-I-L-V-V-G-L-G-N-I-G-V-E-Y-E-N-T-R-H-N-V-G-F-M-L-I-D-L-L-L-K-E-S-N-F-T-N-L-T-N-S-K-F-K-G-E-L-F-K-I-G-S-S-L-L-L-L-K-P-S-T-Y-M-N-N-S-G-L-S-V-K-A-V-N-D-F-Y-K-C-E-R-M-I-V-I-H-D-D-I-D-I-N-L-G-A-L-R-F-K-K-G-G-S-S-G-G-H-N-G-L-K-S-I-D-T-L-C-G-N-D-Y-E-R-V-R-I-G-V-G-K-G-E-N-V-I-S-H-V-L-G-K-F-K-S-E-E-E-I-T-L-S-K-V-L-E-H-A-K-K-A-L-L-E-L-I-E-N-D-D-L-S-A-I-S-S-K-Y-S-L-K-A"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-L-E-G-I-V-R-E-S-I-G-R-K-A-A-K-A-L-K-R-D-G-Y-L-I-A-N-I-Y-G-K-G-L-E-N-I-N-A-A-F-K-V-N-E-F-I-K-E-V-R-K-K-T-T-L-I-F-D-V-K-V-G-S-Q-T-L-S-V-V-V-V-D-Y-Q-K-D-P-V-T-A-E-L-K-H-V-D-L-K-V-A-Q-K-G-V-I-S-K-Y-M-V-P-V-K-I-T-G-T-A-I-G-L-K-N-K-G-V-L-I-Q-S-K-R-R-L-K-V-K-C-A-A-E-N-L-P-N-F-F-E-L-D-V-S-K-L-D-V-G-D-A-L-L-V-R-D-I-V-V-P-A-G-V-T-M-I-D-A-D-R-V-A-V-V-G-V-E-K-A-R"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-Q-K-E-P-M-S-Q-F-G-Y-D-K-L-A-A-E-L-K-D-L-K-D-N-Q-R-P-A-V-V-I-E-I-D-T-A-R-S-H-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-K-Q-A-L-I-E-S-R-I-A-E-L-S-D-L-L-A-R-A-Q-V-I-D-P-S-S-Y-E-H-D-S-V-K-F-G-S-S-V-V-I-M-D-L-D-T-E-K-E-S-K-Y-T-L-V-G-I-C-E-G-N-L-D-K-G-Y-I-S-I-A-S-P-I-A-K-A-M-L-G-K-K-E-G-D-D-F-K-V-R-L-P-K-G-E-S-E-F-E-I-L-S-I-N-Y-E-P-L-K-F"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-T-G-V-V-R-R-R-R-H-K-K-V-L-K-L-A-R-G-F-Y-S-G-R-R-K-H-F-R-K-A-K-E-Q-L-E-R-S-L-V-Y-A-Y-R-D-R-R-R-K-K-R-D-F-R-R-L-W-I-V-R-I-N-A-A-C-R-L-N-D-L-S-Y-S-R-F-I-N-G-L-K-K-A-G-I-E-L-D-R-K-I-L-A-D-L-A-M-N-D-A-A-A-F-A-K-I-A-E-A-A-K-K-A-L"} +{"text": "### FUNCTION Oxygen-binding protein May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes The oxygen-binding site contains two iron atoms ### SEQUENCE -M-T-Y-N-E-K-I-I-S-M-N-N-D-L-L-D-H-Q-H-K-E-L-F-E-I-S-K-K-L-S-L-M-N-Q-R-H-V-G-T-K-E-L-K-I-V-L-R-E-L-L-I-M-I-N-R-H-F-S-D-E-E-A-F-M-R-E-I-E-Y-P-Y-I-N-H-H-T-R-I-H-R-K-I-I-L-E-I-E-E-I-I-I-S-E-A-K-F-V-N-I-M-T-E-K-L-N-L-V-V-Q-D-F-I-F-K-H-T-A-K-E-D-S-K-I-V-K-Y-Y-E-E-K-F-K-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-N-E-I-F-N-K-Q-K-T-Q-S-E-K-S-L-E-A-L-K-K-D-F-T-T-L-R-T-G-K-V-N-I-H-I-L-D-H-I-T-V-D-Y-Y-G-T-Q-T-P-L-N-Q-V-A-T-V-L-A-S-D-A-S-T-I-S-I-T-P-W-E-K-P-L-L-K-T-I-E-S-A-I-A-A-A-N-I-G-V-N-P-N-N-D-G-E-S-V-K-L-F-F-P-P-M-T-R-E-Q-R-E-E-N-V-K-Q-A-K-A-M-G-E-K-A-K-V-S-I-R-N-I-R-K-D-A-N-D-A-V-K-K-L-E-K-D-K-A-I-S-E-D-E-A-K-K-A-Y-D-E-V-Q-K-L-T-D-T-Y-T-T-K-I-D-E-G-V-K-S-K-E-S-E-L-L-K-V"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-K-E-K-E-V-L-L-N-E-E-I-R-A-D-E-I-R-C-V-G-D-D-G-K-V-Y-G-I-I-S-S-D-E-A-L-E-I-A-N-R-L-G-L-D-L-V-M-I-A-A-D-A-K-P-P-V-C-K-I-M-D-Y-G-K-F-R-Y-Q-Q-E-K-K-Q-K-E-A-K-K-K-Q-K-V-I-D-I-K-E-I-K-L-S-V-K-I-A-Q-N-D-I-N-Y-K-V-K-H-A-L-E-F-L-E-Q-G-K-H-V-R-F-R-V-F-L-K-G-R-E-M-A-T-P-E-A-G-V-A-L-L-E-K-I-W-T-M-I-E-N-E-A-N-R-D-K-E-P-N-F-E-G-R-Y-V-N-M-L-V-T-P-K-K-A"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-V-R-K-I-I-T-Y-P-N-P-R-L-F-L-N-S-E-I-V-N-K-F-D-T-E-L-H-T-L-L-D-D-M-Y-E-T-M-I-A-S-N-G-V-G-L-A-A-I-Q-V-D-I-P-L-R-V-L-L-V-N-I-F-D-E-N-D-E-Q-K-K-E-D-L-L-E-I-I-N-P-E-I-I-P-L-D-E-E-M-I-T-C-T-E-G-C-L-S-V-P-D-F-F-E-E-V-K-R-Y-N-H-I-L-L-K-Y-Q-D-R-F-G-E-F-K-E-L-E-A-K-G-F-L-A-V-A-I-Q-H-E-N-D-H-L-N-G-H-L-F-I-E-K-I-S-F-A-K-R-Q-K-F-D-K-E-F-K-K-K-K-K-N-H-K-K-E-K"} +{"text": "### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-D-F-Y-S-L-I-F-L-S-C-A-L-G-M-D-A-F-A-V-S-L-C-K-G-F-S-V-K-K-L-H-L-K-H-Y-L-I-V-G-I-Y-F-G-G-F-Q-A-L-M-P-T-I-G-Y-F-I-G-I-T-F-A-S-F-I-A-S-I-D-H-W-I-A-F-I-L-L-S-L-I-G-L-K-M-I-K-E-S-L-E-N-E-N-C-D-S-N-A-N-Q-F-G-F-K-T-M-L-A-L-A-I-A-T-S-I-D-A-L-A-V-G-V-S-F-A-F-L-N-V-N-L-L-L-A-I-F-L-I-G-I-I-T-F-I-L-C-I-I-A-L-K-I-G-N-K-F-G-I-Y-L-K-N-K-A-E-L-L-G-G-L-V-L-I-I-L-G-V-K-I-L-I-E-H-L-F-F-D"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-E-I-H-P-E-Y-V-E-C-K-V-S-C-A-C-G-N-T-F-T-T-K-S-N-K-A-E-L-R-V-D-I-C-S-N-C-H-P-F-F-T-G-S-E-K-I-V-D-A-A-G-R-V-E-K-F-K-K-K-Y-A-M-Q"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-N-L-E-A-L-C-K-E-A-G-L-S-F-Y-D-D-E-L-V-S-E-N-G-R-K-I-Y-R-I-Y-V-Q-K-E-G-G-V-N-L-D-D-C-A-R-L-S-E-I-L-S-P-I-F-D-V-E-S-P-V-N-G-E-Y-F-L-E-V-S-S-P-G-L-E-R-K-L-S-K-I-E-H-F-A-K-S-I-G-E-L-V-K-I-T-T-N-E-K-E-K-F-E-A-K-I-I-A-V-D-D-E-N-I-T-L-E-N-L-E-N-K-E-K-T-T-I-N-F-N-D-I-K-K-A-R-T-F-V-E-W"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-N-P-S-E-I-K-K-L-R-T-E-S-I-L-K-E-L-I-P-E-A-L-A-N-L-D-D-E-N-L-K-N-L-C-V-V-D-V-E-C-K-K-G-R-Y-D-A-F-V-Y-L-D-K-M-F-F-N-V-H-E-Q-E-K-I-L-S-S-L-K-K-A-S-R-A-L-Q-N-Y-C-M-S-E-Q-G-W-Y-R-C-P-N-F-H-F-K-F-D-D-R-L-E-Y-Q-N-H-M-D-A-L-F-E-K-I-K-K-D-K-N-E-S"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-E-N-N-L-Q-V-N-I-F-C-I-Q-K-S-D-E-F-K-T-C-S-E-K-Y-S-K-L-I-S-K-Y-A-T-L-K-E-I-N-V-F-N-K-K-I-A-L-A-Q-N-L-N-A-I-E-A-K-K-S-Y-E-E-A-F-M-P-Y-K-K-G-Y-C-I-A-L-D-E-K-G-K-D-L-T-S-I-E-F-A-K-L-I-Q-D-K-N-E-L-S-F-F-I-G-G-A-Y-G-L-R-E-E-F-N-Q-S-L-D-F-R-L-S-L-S-K-L-T-L-A-H-Q-F-V-K-T-L-L-L-E-Q-I-Y-R-A-F-C-I-N-N-N-H-P-Y-H-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-L-S-D-E-K-C-D-F-L-E-S-I-A-S-F-L-S-P-K-D-V-E-L-V-F-V-D-S-K-E-M-Q-E-I-N-L-E-Q-R-K-Q-D-K-T-T-D-V-L-S-F-P-L-E-N-I-D-E-S-L-P-L-G-S-V-V-I-N-V-D-L-A-K-E-K-A-K-E-L-G-H-S-Y-E-E-E-I-S-L-L-F-I-H-A-M-L-H-L-L-G-F-D-H-E-N-D-N-G-E-M-R-E-K-E-K-E-L-I-E-H-F-N-L-P-K-S-L-I-V-R-T-L-E-D"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-N-D-L-I-N-F-E-I-V-T-P-L-G-V-I-Y-Q-G-E-V-K-S-V-T-L-P-G-S-E-G-E-F-G-V-L-K-G-H-A-A-L-V-S-S-L-K-S-G-V-I-D-I-E-K-A-D-L-N-H-E-L-I-A-I-D-A-G-H-A-K-V-D-E-D-K-I-C-V-L-A-K-G-A-V-W-V-C-G-S-D-E-S-E-I-E-K-N-L-A-Q-A-K-D-L-I-K-S-M-S-S-D-N-A-A-L-A-A-T-F-S-K-L-D-N-A-R-M-H"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-P-R-K-P-S-K-K-V-G-P-Q-K-R-P-S-A-E-K-R-V-I-T-S-K-K-K-Q-L-R-N-Q-S-F-K-S-R-V-K-T-T-L-K-K-F-E-L-A-V-Q-S-G-D-V-A-S-I-S-A-G-L-S-S-V-Y-S-I-A-D-K-A-V-K-R-G-I-F-K-K-G-K-A-D-R-V-K-A-R-A-S-G-R-A-C-P-T-A"} +{"text": "### FUNCTION Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin ### SEQUENCE -M-Y-R-L-D-V-T-N-F-R-V-W-V-S-I-G-V-S-E-Q-E-R-Y-H-K-Q-P-I-L-V-S-V-S-L-V-F-R-E-E-P-K-V-C-S-T-D-E-I-S-D-G-I-C-Y-A-A-L-V-S-L-I-E-Q-T-A-A-N-H-P-C-A-L-L-E-R-L-A-K-V-L-L-E-K-L-E-E-S-L-A-Q-F-V-C-K-I-D-L-R-V-S-K-E-R-P-P-I-P-N-L-L-S-P-V-S-F-S-I-S-K-E-V-P"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-V-Q-I-V-S-Q-D-N-F-A-D-S-I-A-S-G-L-V-L-V-D-F-F-A-E-W-C-G-P-C-K-M-L-T-P-V-L-E-A-L-A-A-E-L-P-Y-V-T-I-L-K-L-D-I-D-A-S-P-R-P-A-E-Q-F-G-V-S-S-I-P-T-L-I-L-F-K-D-G-K-E-V-E-R-S-V-G-L-K-D-K-D-S-L-V-K-L-I-S-K-H-Q"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-K-D-P-Y-D-V-V-K-R-H-Y-V-T-E-K-A-K-M-L-E-G-L-S-L-G-G-G-E-G-K-K-K-G-S-F-C-K-D-P-K-Y-T-F-V-V-A-G-D-A-T-K-P-M-I-A-E-A-I-E-A-I-Y-S-N-K-G-V-K-V-K-K-V-N-T-V-C-V-K-P-Q-P-T-R-I-F-R-G-K-R-K-G-R-T-A-G-F-K-K-A-I-V-T-F-V-D-G-H-S-I-G"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-F-K-A-T-A-R-Y-I-R-V-Q-P-R-K-A-R-L-A-A-G-L-M-R-N-R-S-V-V-E-A-Q-Q-Q-L-S-F-S-Q-M-K-A-G-R-C-L-K-K-V-L-D-S-A-V-A-N-A-E-S-N-E-N-V-K-R-E-N-L-C-V-V-E-V-R-V-D-A-G-P-M-F-K-R-V-K-S-K-S-R-G-G-R-A-P-V-L-K-R-T-S-H-L-T-V-I-V-G-E-R-G-Q"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-F-R-K-Q-Q-K-G-Q-F-A-G-L-S-K-G-A-T-F-V-D-F-G-E-F-G-M-Q-T-L-E-R-G-W-I-T-S-R-Q-I-E-A-C-R-V-A-I-N-R-Y-L-K-R-K-G-K-V-W-I-R-V-F-P-D-K-S-V-T-K-K-P-A-E-T-R-M-G-K-G-K-G-A-P-D-H-W-V-A-V-V-R-P-G-R-I-L-F-E-V-A-N-V-S-K-E-D-A-Q-D-A-L-R-R-A-A-A-K-L-G-I-R-T-R-F-V-K-R-V-E-R-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-S-D-V-R-G-R-R-K-T-K-I-G-V-V-V-S-S-K-M-E-K-T-V-V-V-R-V-E-R-V-Y-S-H-P-Q-Y-A-K-V-V-R-D-S-S-K-Y-Y-A-H-N-E-L-D-V-K-E-G-D-T-V-R-I-Q-E-T-R-P-L-S-K-T-K-R-W-R-V-V-D-R-V-N"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-Q-L-K-V-A-D-N-T-G-A-K-K-V-K-C-F-K-V-L-G-G-S-R-R-R-Y-A-T-V-G-D-V-I-V-C-S-V-R-D-V-E-P-D-S-S-V-K-K-G-D-V-V-K-A-V-I-V-R-T-R-N-D-I-R-R-K-D-G-S-T-L-R-F-D-T-N-S-C-V-I-I-D-D-K-G-N-P-K-G-T-R-I-F-G-P-V-A-R-E-I-R-D-R-G-F-I-K-I-S-S-L-A-P-E-V-I"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-R-R-S-V-C-V-G-D-T-V-Y-V-L-A-G-N-D-K-G-K-Q-G-K-V-L-R-C-L-K-D-K-V-V-V-E-G-I-N-V-R-V-K-N-I-K-R-S-Q-E-N-P-K-G-K-R-I-N-I-E-A-P-L-H-I-S-N-V-R-L-S-I-D-N-Q-P-A-R-L-F-V-K-V-T-E-K-G-R-E-L-W-N-K-H-S-D-G-S-S-S-L-Y-R-L-V-R-E-R-K-G"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-R-L-K-K-L-Y-T-E-E-I-R-K-T-L-Q-D-K-F-Q-Y-E-N-V-M-Q-I-P-V-L-K-K-I-V-I-S-M-G-L-A-E-A-A-K-D-K-N-L-F-Q-S-H-L-E-E-L-A-V-I-S-G-Q-K-P-L-V-T-R-A-K-N-S-I-A-G-F-K-L-R-E-G-Q-G-I-G-A-K-V-T-L-R-G-I-R-M-Y-D-F-M-D-R-F-C-N-I-V-S-P-R-I-R-D-F-R-G-F-S-C-K-G-D-G-R-G-C-Y-S-L-G-L-D-D-Q-Q-I-F-P-E-V-D-L-D-R-V-K-R-S-Q-G-M-N-I-T-W-V-T-T-A-Q-T-D-A-E-C-L-T-L-L-E-C-M-G-L-R-F-K-K-A-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-I-T-S-D-S-I-A-N-L-L-T-R-I-R-N-A-L-M-A-E-H-L-Y-I-D-I-E-H-S-K-M-L-E-A-I-V-R-I-L-K-Q-H-G-F-V-A-H-F-L-V-K-E-E-N-R-K-R-L-M-R-V-F-L-R-Y-G-E-D-R-R-P-V-I-H-A-L-K-R-V-S-K-P-S-R-R-V-Y-V-S-A-A-K-I-P-Y-V-F-G-N-M-G-I-A-V-L-S-T-P-Q-G-V-L-E-G-S-E-A-R-A-K-N-V-G-G-E-L-L-C-L-V-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-K-A-R-D-P-I-V-L-P-Q-G-V-E-V-S-I-Q-N-D-E-I-S-V-K-G-P-K-G-S-L-T-Q-V-L-A-K-E-V-E-I-A-V-K-G-N-E-V-F-V-S-P-A-A-H-I-I-D-R-P-G-R-M-Q-G-L-Y-W-A-L-I-A-N-M-V-K-G-V-H-L-G-F-E-K-R-L-E-M-I-G-V-G-F-R-A-S-V-Q-G-S-F-L-D-L-S-I-G-V-S-H-P-T-K-M-P-I-P-T-G-L-E-V-S-V-E-K-N-T-L-I-S-I-K-G-I-N-K-Q-L-V-G-E-F-A-A-C-V-R-A-K-R-P-P-E-P-Y-K-G-K-G-I-R-Y-E-N-E-Y-V-R-R-K-A-G-K-A-A-K-T-G-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-E-S-S-L-Y-K-K-T-S-G-K-A-R-R-A-L-R-V-R-K-A-L-K-G-S-S-L-K-P-R-L-S-V-V-K-T-N-K-H-I-Y-V-Q-L-I-D-D-V-E-G-K-T-L-A-S-I-S-T-L-A-K-I-S-K-T-S-G-L-T-K-K-N-Q-D-N-A-K-A-L-G-V-K-I-A-E-L-G-K-S-L-Q-V-D-R-I-V-F-D-R-G-A-H-K-Y-H-G-V-V-A-M-V-A-D-G-A-R-E-G-G-L-Q-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-I-K-L-E-Y-L-Q-D-P-S-P-R-K-R-R-T-K-L-L-G-R-G-P-S-S-G-H-G-K-T-S-G-R-G-H-K-G-D-G-S-R-S-G-Y-K-R-R-F-G-Y-E-G-G-G-V-P-L-Y-R-R-V-P-T-R-G-F-S-H-K-R-F-D-K-C-V-E-E-I-T-T-Q-R-L-N-G-I-F-E-N-G-E-E-V-S-L-E-T-L-K-Q-R-K-V-I-H-R-E-T-S-R-V-K-V-I-L-K-G-A-L-D-K-K-L-V-W-K-D-A-A-I-V-L-S-E-G-V-K-S-L-I-E-T-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-P-R-I-I-G-I-D-I-P-A-K-K-K-L-K-I-S-L-T-Y-I-Y-G-I-G-P-A-L-S-E-E-I-I-A-R-L-Q-L-N-P-E-A-R-A-A-E-L-T-E-E-E-V-G-R-L-N-A-L-L-Q-S-D-Y-V-V-E-G-D-L-R-R-R-V-Q-S-D-I-K-R-L-I-T-I-H-A-Y-R-G-Q-R-H-R-L-S-L-P-V-R-G-Q-R-T-K-T-N-S-R-T-R-K-G-K-R-K-T-V-A-G-K-K-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-V-K-N-Q-T-Q-K-K-G-V-K-R-K-Q-V-K-N-I-P-S-G-V-V-H-V-K-A-T-F-N-N-T-I-V-T-I-T-D-P-A-G-N-V-I-S-W-A-S-A-G-K-V-G-Y-S-G-S-R-K-S-S-A-F-A-A-T-V-A-A-Q-D-A-A-K-T-A-M-S-S-G-L-K-E-V-E-V-S-L-K-G-T-G-A-G-R-E-S-A-V-R-A-L-I-S-S-G-L-I-V-S-V-I-R-D-E-T-P-V-P-H-N-G-C-R-P-R-K-R-R-R-V"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-E-Y-I-K-G-K-L-T-H-T-D-E-A-Y-V-V-I-E-S-F-G-I-G-Y-S-I-M-L-S-E-R-F-L-V-D-L-R-E-L-M-H-Q-E-V-L-I-Y-V-H-S-V-I-R-E-T-E-H-S-L-Y-G-F-S-S-R-A-E-R-E-C-F-R-L-L-I-S-F-S-G-I-G-P-K-T-G-L-A-I-L-N-M-F-P-L-Q-E-L-C-S-V-A-R-L-E-N-V-K-A-I-A-S-V-P-G-I-G-K-K-T-A-E-K-L-M-V-D-L-K-Q-K-L-P-A-L-M-P-L-Y-L-E-E-P-V-V-A-S-S-S-T-T-T-S-F-K-E-G-I-G-A-L-M-N-L-G-F-S-R-L-A-A-D-R-M-M-T-E-A-V-K-E-L-S-E-D-A-S-V-A-E-L-L-P-V-A-L-R-K-G"} +{"text": "### FUNCTION In elementary bodies ### SEQUENCE -M-K-K-T-A-L-L-A-A-L-C-S-V-V-S-L-S-S-C-C-R-I-V-D-C-C-F-E-D-P-C-A-P-I-K-C-S-P-C-E-S-K-K-R-E-V-N-G-G-C-N-S-C-N-G-Y-V-P-S-C-K-P-C-G-G-E-L-D-H-E-T-K-Q-G-P-Q-A-R-G-I-Q-A-D-G-R-C-R-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-A-A-E-K-K-V-I-P-G-D-P-V-Y-G-S-V-V-L-E-R-F-I-N-K-V-M-L-H-G-K-K-S-I-A-R-K-I-V-Y-G-A-L-E-R-F-A-K-R-L-G-L-E-N-P-L-E-G-F-E-E-A-L-E-N-A-K-P-I-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-A-P-D-R-R-S-C-L-A-M-Q-W-I-I-K-H-A-R-S-K-P-G-K-C-M-E-I-G-L-A-N-E-L-I-D-C-F-N-K-Q-G-A-T-I-K-K-R-E-D-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-K-W"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-L-I-L-D-R-S-S-P-Q-I-F-I-S-N-E-Q-Q-D-V-D-I-D-L-Q-S-V-Q-R-L-V-I-L-F-L-E-L-Q-K-V-S-T-D-Q-V-Y-I-Y-F-L-S-D-A-A-L-A-Q-L-H-D-E-Q-F-S-D-P-S-L-T-D-T-I-T-L-P-I-D-R-P-G-I-Q-S-F-P-H-V-L-G-E-A-F-V-S-P-R-A-A-M-R-F-L-G-Q-Y-T-E-A-Q-L-Y-H-E-I-S-R-Y-V-V-H-S-L-L-H-M-L-G-Y-D-D-Q-T-D-E-D-K-R-I-M-R-E-Q-E-D-S-S-L-T-F-L-A-Q-N-Q-A-L-L-H-P-T-V"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-E-P-Y-A-V-V-Q-T-G-N-K-Q-Y-Q-V-R-K-G-D-V-I-D-V-E-L-L-D-G-I-S-E-E-N-K-E-V-L-F-Q-E-V-L-F-V-F-D-G-E-K-A-S-V-G-S-P-T-V-G-N-A-V-V-K-G-E-L-I-S-F-V-R-G-E-K-V-V-A-Y-K-Y-K-K-R-K-N-Y-H-K-K-I-G-H-R-Q-N-Y-L-R-V-K-I-C-D-L-V-M"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-L-C-P-F-C-N-H-G-E-L-K-V-I-D-S-R-N-S-P-E-A-N-A-I-K-R-R-R-E-C-L-R-C-S-Q-R-F-T-T-F-E-T-V-E-L-T-I-Q-V-L-K-R-D-G-R-Y-E-N-F-Q-E-A-K-L-I-N-G-L-K-A-A-S-S-H-T-R-I-G-Q-E-Q-V-Q-A-I-A-S-N-I-K-Q-D-L-L-G-K-Q-N-R-E-I-S-T-K-E-I-G-E-L-V-M-K-Y-L-K-K-A-D-M-I-A-Y-I-R-F-A-C-V-Y-R-R-F-R-D-V-G-E-L-M-E-V-L-L-S-A-T-P-D-G-E-K"} +{"text": "### FUNCTION Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-uracil ### SEQUENCE -M-F-S-G-I-I-Q-E-V-A-R-V-D-L-I-H-H-Y-G-D-S-M-E-I-G-I-F-A-R-N-L-V-D-G-V-P-G-S-S-I-A-V-D-G-I-C-L-T-L-V-K-R-E-F-E-L-L-F-F-D-V-T-E-E-T-M-A-C-T-T-I-K-N-Y-T-V-G-S-M-V-N-L-E-R-S-V-R-L-G-D-E-I-G-G-H-F-V-S-G-H-V-C-G-V-G-T-I-I-A-V-E-K-S-Y-M-F-F-K-A-P-T-N-L-V-P-Y-V-L-E-K-G-F-I-A-I-D-G-I-S-L-T-I-A-Q-V-R-G-D-I-F-S-V-S-V-I-P-E-T-R-A-R-T-S-L-G-Y-K-Q-V-G-S-H-V-N-M-E-P-D-M-M-T-K-M-Q-V-D-T-V-M-R-F-Q-A-E-K-I-G-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-R-D-L-E-Y-Y-D-S-P-I-L-R-K-V-A-A-P-I-D-E-I-T-D-E-L-R-Q-L-V-L-D-M-S-E-T-M-T-F-Y-K-G-V-G-L-A-A-P-Q-V-G-H-S-V-A-L-F-I-M-G-V-E-K-E-L-D-D-G-E-L-I-F-C-D-F-P-K-V-F-I-N-P-V-I-T-Q-K-S-E-Q-L-V-Y-G-N-E-G-C-L-S-I-P-G-L-R-G-E-V-A-R-P-D-K-I-T-V-T-A-K-N-L-D-G-Q-P-F-S-M-T-L-E-G-F-L-A-R-I-V-M-H-E-T-D-H-L-H-G-V-L-Y-I-D-R-M-S-D-K-D-K-T-K-Q-F-K-N-N-L-E-K-I-R-R-K-Y-S-I-L-R-G-L"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-G-T-Q-L-V-L-G-S-S-S-K-I-R-K-A-V-L-E-A-F-R-I-P-F-I-C-V-S-S-D-F-D-E-R-S-I-T-Y-S-G-D-P-F-E-Y-T-R-E-L-A-W-N-K-A-N-A-V-R-S-Q-G-F-S-D-S-L-I-I-T-A-D-T-V-V-V-Y-E-G-E-V-F-N-K-P-E-S-E-E-H-A-V-E-M-L-R-T-L-S-G-T-S-H-S-V-I-T-S-L-V-L-M-Q-N-E-K-V-A-S-A-S-E-T-T-Q-V-S-F-I-D-I-P-P-Q-H-L-K-T-Y-V-Q-A-F-S-S-L-K-R-C-G-G-Y-C-V-Q-D-G-G-G-L-I-I-K-Q-I-E-G-C-V-Y-N-I-Q-G-L-P-I-K-T-L-N-Q-L-L-M-E-F-N-I-S-L-W-D-Y-L-A"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-S-G-G-D-D-L-V-L-H-N-P-V-E-D-G-E-L-S-A-I-F-M-I-R-N-P-S-G-I-H-V-R-P-A-G-T-I-V-K-L-F-D-G-E-D-C-E-A-T-F-T-Y-L-G-K-T-V-N-A-R-S-V-M-S-I-L-M-L-G-A-S-Y-N-G-E-I-T-V-R-I-K-G-P-S-A-S-R-V-M-Q-K-L-A-E-V-F-N-S-G-F-G-E-L"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-G-S-G-Y-A-K-K-K-K-E-A-K-L-M-E-R-Q-F-M-E-M-E-A-S-L-E-Q-K-R-F-S-G-E-A-G-N-G-L-V-S-V-T-I-N-G-K-C-N-L-V-D-V-K-I-K-P-D-C-L-D-P-E-D-P-E-V-V-A-D-L-F-R-A-A-F-K-A-A-K-A-A-L-D-S-E-M-S-A-M-H-M-G-M-P-F"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-T-K-K-A-K-N-V-E-K-V-P-F-E-D-A-M-K-R-L-E-E-I-I-D-L-M-N-Q-P-T-T-A-L-E-A-S-L-A-L-Y-E-E-A-D-Q-L-M-R-I-C-E-S-R-I-Q-E-V-E-A-R-I-K-Q-L-S-D-Q-R-S-E-S"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-F-K-W-Y-V-V-Q-V-F-T-A-Q-E-K-K-V-K-K-S-L-E-D-F-K-E-A-S-G-M-S-D-F-I-Q-Q-I-I-L-P-S-E-N-V-M-E-V-K-K-G-E-H-K-I-V-E-K-Y-I-W-P-G-Y-L-L-V-K-M-H-L-T-D-E-S-W-S-Y-V-K-K-T-Q-G-V-V-E-F-L-G-G-G-A-P-V-A-L-S-E-E-E-V-K-N-I-L-A-D-L-E-E-K-K-S-G-V-V-Q-K-H-K-F-E-V-G-S-Q-V-K-I-N-D-G-V-F-V-N-F-V-G-V-V-S-E-V-F-H-D-K-G-R-L-S-V-M-V-S-I-F-G-R-E-T-R-V-D-D-L-E-F-W-Q-V-E-E-V-A-P-G-Q-E-S-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-S-N-K-K-I-I-K-I-I-K-L-Q-I-P-G-G-K-A-N-P-A-P-P-I-G-P-A-L-G-A-A-G-V-N-I-M-G-F-C-K-E-F-N-A-A-T-Q-D-R-P-G-D-L-L-P-V-V-I-T-V-Y-S-D-K-T-F-S-F-V-M-K-Q-P-P-V-S-S-L-I-K-K-A-L-G-L-E-S-G-S-K-I-P-N-R-N-K-V-G-K-L-A-R-A-Q-I-T-A-I-A-E-Q-K-M-K-D-M-D-V-V-L-L-E-S-A-E-R-M-V-E-G-T-A-R-S-M-G-V-D-V-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-K-E-E-K-K-L-L-L-R-E-V-E-E-K-I-T-A-S-Q-G-F-I-L-L-R-Y-L-G-F-T-A-A-H-S-R-S-F-R-N-N-L-S-G-V-S-A-E-F-E-V-L-K-K-K-I-F-F-K-A-L-E-S-S-G-V-E-M-D-P-E-D-S-E-G-H-L-G-V-V-F-A-Y-G-D-P-V-S-A-A-K-Q-V-L-D-F-N-K-Q-H-N-D-S-L-V-F-L-A-G-R-I-D-N-A-S-L-S-G-K-E-V-E-A-V-A-K-L-P-S-M-K-E-L-R-Q-Q-V-V-G-L-I-A-A-P-M-S-Q-V-V-G-I-M-N-S-V-L-S-G-V-I-S-C-V-D-Q-K-A-E-K-T-Q-E"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-L-K-Y-P-D-Y-I-S-K-L-I-S-F-L-K-K-L-P-G-I-G-F-K-S-A-E-K-I-A-F-E-L-L-E-W-D-P-S-Q-V-E-A-M-G-L-A-M-Q-E-F-S-A-S-H-A-T-C-P-D-C-F-C-L-K-T-S-K-T-S-S-C-D-F-C-S-E-S-R-D-S-S-F-L-C-I-V-A-T-P-K-D-V-F-S-F-E-K-S-K-I-F-K-G-R-Y-F-V-L-G-N-L-L-S-P-I-T-G-K-H-L-S-L-E-K-L-N-I-L-K-Q-R-I-E-D-F-A-P-K-E-M-I-I-A-L-D-A-T-L-E-G-D-A-T-A-L-F-L-K-Q-E-F-S-H-L-P-I-K-I-S-R-L-A-L-G-M-P-V-G-L-S-F-D-F-I-D-S-N-T-L-A-R-A-F-S-G-R-N-C-F"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-L-E-D-D-V-K-A-I-I-V-D-Q-L-G-V-S-P-E-D-V-K-E-S-S-S-F-I-E-D-L-N-A-D-S-L-D-L-T-E-L-I-M-T-L-E-E-K-F-A-F-E-I-S-E-N-D-A-E-Q-L-R-T-V-G-D-V-I-K-Y-I-Q-E-R-Q-N"} +{"text": "### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-K-R-Y-I-V-G-I-S-G-A-S-G-A-I-L-A-V-T-L-V-S-E-L-A-R-L-G-H-H-V-D-V-I-I-S-P-A-A-Q-K-T-L-Y-Y-E-L-E-T-K-S-F-L-A-T-I-P-S-N-L-H-K-N-I-L-I-H-R-I-T-S-I-E-S-S-L-S-S-G-S-T-L-V-D-A-T-I-I-V-P-C-S-V-A-T-I-A-A-I-S-C-G-L-S-D-N-L-L-R-R-V-A-D-V-A-L-K-E-K-R-P-L-I-L-V-P-R-E-T-P-L-S-A-I-H-L-E-N-L-L-K-L-A-Q-N-G-A-V-I-L-P-P-M-P-T-W-Y-F-R-P-E-T-A-N-D-I-A-N-D-I-V-G-K-I-L-A-I-L-Q-L-D-S-P-L-I-K-R-W-E-N-P-H"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-N-S-M-K-Q-K-E-A-F-L-G-V-D-Y-G-K-K-R-I-G-L-A-F-A-S-A-P-L-L-I-T-L-P-I-G-S-I-N-T-C-S-S-L-A-L-T-A-Q-A-L-I-T-I-I-K-E-R-A-V-T-T-V-V-F-G-N-P-L-P-M-Q-K-S-Y-A-S-S-V-Q-S-E-I-Q-E-L-A-A-L-V-R-D-M-T-S-L-E-V-I-L-W-D-E-R-L-S-S-A-Q-A-E-R-M-L-K-N-D-C-G-L-S-R-K-Q-R-K-N-S-S-D-S-L-A-A-T-L-I-L-S-S-F-L-D-S-R-K-L-Y"} +{"text": "### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-I-K-L-L-R-S-Y-C-L-Y-F-A-W-L-V-S-C-I-G-T-L-M-S-V-Y-Y-S-Y-L-L-N-V-E-P-C-V-L-C-Y-Y-Q-R-I-C-L-F-P-L-V-V-I-L-G-I-S-A-Y-L-D-D-L-S-V-K-I-Y-A-L-P-L-A-L-I-G-F-C-I-A-I-Y-Q-V-C-L-Q-E-I-P-G-M-T-L-D-I-C-G-K-V-S-C-S-T-K-L-F-L-L-G-F-I-T-M-P-M-A-S-A-L-A-F-F-A-I-A-N-L-L-I-F-A-T-K-S-E"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-E-K-R-K-D-T-K-T-T-L-A-K-A-S-D-D-Q-N-K-A-W-Y-V-I-N-A-E-G-K-T-L-G-R-L-S-S-E-V-A-K-I-L-R-G-K-H-K-V-T-F-T-P-H-V-A-M-G-D-G-V-I-V-I-N-A-E-K-V-R-L-T-G-A-K-R-A-Q-K-V-Y-H-Y-Y-T-G-F-I-S-G-M-R-E-V-P-F-E-N-M-I-A-R-K-P-A-Y-V-I-E-H-A-V-K-G-M-L-P-K-T-K-L-G-R-R-Q-M-K-S-L-R-V-V-K-G-S-S-Y-A-Q-Y-E-A-I-K-P-I-V-L-D-A"} +{"text": "### FUNCTION This protein is a component of the acetyl coenzyme A carboxylase complex ### SEQUENCE -M-D-L-K-Q-I-E-K-L-M-I-A-M-G-R-N-K-M-K-R-I-A-I-K-R-D-G-F-E-L-E-L-E-R-D-T-G-P-N-I-Q-E-P-V-F-Y-D-N-R-L-F-A-G-F-T-Q-E-R-P-I-P-S-D-Q-N-L-G-N-P-I-V-K-E-V-G-E-K-K-E-D-K-P-V-E-G-D-F-I-V-S-P-L-V-G-T-F-Y-G-A-P-S-P-E-S-P-A-F-V-K-P-G-D-I-V-S-E-D-T-V-V-C-I-V-E-A-M-K-V-M-N-E-V-K-A-G-M-A-G-R-V-E-E-V-L-I-T-N-G-D-P-V-Q-F-G-S-K-L-F-R-I-V-K-A"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-L-S-S-Q-L-S-V-G-M-F-I-S-T-K-D-G-L-Y-K-V-V-S-V-S-K-V-S-G-S-K-G-D-T-F-I-K-V-A-L-Q-A-A-G-S-D-V-V-V-E-R-N-F-K-A-G-Q-E-V-K-E-A-Q-F-E-P-R-N-L-E-Y-L-Y-L-E-E-D-N-Y-L-F-L-D-L-G-N-Y-E-K-I-Y-I-P-K-E-I-M-K-E-N-A-M-F-L-K-A-G-V-T-I-S-A-L-V-H-E-G-I-V-F-S-M-E-L-P-H-F-L-E-L-M-V-S-K-T-D-F-P-G-D-S-L-S-L-S-G-G-A-K-K-A-L-L-E-T-G-V-E-V-L-V-P-P-F-V-E-I-G-D-V-I-K-V-D-T-R-T-C-E-Y-I-Q-R-V"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-F-G-I-G-T-D-I-I-E-I-D-R-I-R-R-A-Y-H-T-Y-G-D-R-F-L-N-K-I-F-T-K-G-E-Q-A-Y-C-F-S-K-S-D-P-Y-A-S-L-A-V-R-F-A-A-K-E-A-V-S-K-A-L-G-T-G-I-G-K-S-L-K-W-K-E-I-E-I-S-R-G-T-Q-H-P-Q-V-S-V-P-E-S-L-L-A-L-L-E-V-K-R-I-L-L-S-M-S-H-C-R-E-Y-A-T-A-V-A-I-A-E-V-T-N-S-S-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-T-E-N-R-R-M-K-K-V-N-A-M-L-R-E-S-I-A-K-V-I-L-K-D-V-K-H-P-K-I-S-N-R-W-I-T-I-T-R-V-S-L-S-R-D-L-Q-S-A-R-V-Y-V-S-I-M-P-H-E-N-S-Q-E-E-T-L-A-A-L-K-A-S-A-G-F-I-A-C-Q-A-S-K-D-V-V-L-K-Y-F-P-D-L-N-F-Y-M-E-D-I-F-S-P-Q-D-H-I-E-S-L-L-L-K-I-A-E-Q-D-K-K-L-T-H-N-N-N-N-S-S-E-L-H-D"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-V-K-E-I-V-S-N-R-K-A-F-H-N-Y-E-V-L-E-T-F-D-A-G-I-V-L-T-G-T-E-I-K-S-L-R-D-H-G-G-N-L-G-D-A-Y-V-T-I-S-K-G-E-A-W-L-L-Q-S-S-I-A-P-Y-R-F-G-N-I-N-N-H-E-E-R-R-K-R-K-L-L-L-H-K-Y-E-L-Q-K-L-D-S-R-V-S-Q-K-G-L-T-I-I-P-L-S-F-F-F-S-K-G-F-V-K-V-R-I-G-C-C-R-G-K-K-S-H-D-K-R-Q-A-L-I-E-R-E-K-N-R-E-L-A-A-A-M-K-R-S-Y-R"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-G-N-L-I-K-E-L-Q-D-E-Q-C-R-T-D-L-V-D-F-C-V-G-D-T-I-R-V-A-T-N-I-S-E-G-G-K-E-R-V-Q-V-F-Q-G-T-V-M-A-R-K-G-G-G-A-G-E-T-V-S-L-H-R-V-A-Y-G-E-G-M-E-K-S-F-L-L-N-S-P-K-V-V-S-I-E-V-V-K-R-G-K-V-S-R-A-R-L-F-Y-L-R-G-K-T-G-K-A-A-K-V-K-E-L-I-G-P-R-A-A-K-K"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-T-Q-S-Y-V-N-K-E-E-I-I-S-L-A-K-N-A-A-L-E-L-E-E-A-H-V-E-E-F-V-T-S-M-N-N-V-I-A-L-M-Q-E-V-V-A-I-D-I-S-D-I-I-L-E-A-T-V-H-H-F-V-G-P-E-D-L-R-E-D-M-V-T-S-D-F-T-R-E-E-F-L-A-N-V-P-V-S-L-G-G-L-V-K-V-P-T-V-I-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-A-T-G-S-V-A-S-R-A-R-R-K-R-I-L-K-Q-A-K-G-F-W-G-D-R-K-G-H-F-R-Q-S-R-S-S-V-M-R-A-M-A-F-N-Y-M-H-R-K-D-R-K-G-D-F-R-S-L-W-I-S-R-L-N-V-A-S-R-I-H-G-L-S-Y-S-R-L-I-N-G-L-K-Q-A-G-I-N-L-N-R-K-M-L-S-E-M-A-I-H-D-P-Q-G-F-A-L-V-A-A-Q-A-K-L-A-L-E-A-S-I-Q-G"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-A-L-N-L-K-I-N-R-Q-I-R-A-P-R-V-R-V-I-G-S-S-G-E-Q-L-G-I-L-S-I-K-E-A-L-D-L-A-R-E-A-D-L-D-L-V-E-V-A-S-N-S-E-P-P-V-C-K-I-M-D-Y-G-K-Y-R-Y-D-V-T-K-K-E-K-D-S-K-K-A-Q-H-Q-V-R-V-K-E-V-K-L-K-P-N-I-D-D-N-D-F-L-T-K-V-K-Q-A-R-A-F-I-E-K-G-N-K-V-K-V-S-C-M-F-R-G-R-E-L-A-Y-P-E-H-G-H-K-V-V-Q-R-M-C-Q-G-L-E-D-V-G-F-V-E-S-E-P-K-L-N-G-R-S-L-I-C-V-I-A-P-G-T-L-K-T-K-K-K-Q-E-K-V-H-A-Q-D-E-K-Q"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-I-M-S-V-M-A-S-D-S-A-R-A-V-V-C-T-S-R-P-F-P-K-Q-K-L-R-E-L-V-L-Q-A-L-Y-A-L-E-M-A-P-K-G-E-D-S-L-V-S-L-L-M-T-E-A-S-V-S-K-K-N-V-L-Y-A-L-M-F-C-K-A-I-R-A-N-Q-S-E-L-D-A-L-L-N-A-T-I-R-T-T-T-L-A-N-L-T-I-I-E-R-N-I-L-R-M-M-L-F-E-H-Q-Q-N-Q-E-S-S-P-I-P-T-A-V-L-I-A-E-T-T-R-L-I-K-K-F-S-Y-V-E-G-S-S-L-I-L-A-V-L-G-S-I-F-D-Q-V-A-Q-E-P-A-S-M-C-G"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-K-K-K-T-G-Q-L-Y-E-G-A-Y-V-F-S-V-T-L-S-E-D-A-R-R-K-A-L-E-K-V-T-S-G-I-T-N-Y-G-G-E-V-L-K-I-H-D-Q-G-R-K-K-L-A-Y-T-I-R-G-A-R-E-G-Y-Y-Y-F-I-Y-F-T-V-A-P-E-A-I-S-E-L-W-R-E-Y-H-L-N-E-D-L-L-R-F-M-T-L-K-A-S-A-V-K-E-V-L-E-F-A-T-L-P-E"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-E-L-V-V-Q-S-R-E-T-D-K-K-S-V-I-K-K-I-R-Q-Q-G-G-I-P-A-V-L-Y-S-G-G-K-S-L-A-N-V-V-I-D-A-R-V-F-N-K-F-L-S-T-L-E-S-G-A-L-A-S-T-V-F-T-L-S-Y-E-G-R-E-I-K-A-L-V-K-D-I-Q-Y-H-V-T-T-Y-D-V-I-H-L-D-F-E-E-L-V-E-D-R-E-V-R-L-N-I-P-I-R-C-I-N-T-V-D-C-V-G-V-K-L-G-G-S-L-R-Q-V-I-R-Y-M-R-V-V-C-K-P-K-D-I-V-P-F-L-E-L-D-V-Q-S-L-G-L-S-Q-T-L-K-L-S-D-I-R-I-P-E-G-I-K-P-V-T-P-L-K-E-V-A-V-T-V-A-R-R"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-A-V-A-R-E-V-K-R-R-K-L-V-E-A-N-F-Q-K-R-A-E-L-R-K-L-A-K-S-L-S-V-S-E-E-E-R-E-R-A-R-E-A-L-N-K-M-K-R-D-T-S-P-S-R-L-H-N-R-C-L-L-T-G-R-P-R-G-Y-L-R-K-F-A-I-S-R-I-C-F-R-Q-M-A-S-M-G-D-I-P-G-V-I-K-A-S-W"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-H-R-L-T-L-P-K-S-A-R-L-L-K-R-K-Q-F-V-Y-V-Q-R-C-G-Q-Y-C-R-T-D-Q-A-T-L-R-I-V-P-S-R-H-S-N-I-R-K-V-G-V-T-V-S-K-K-F-G-K-A-H-Q-R-N-R-F-K-R-I-V-R-E-A-F-R-H-V-R-P-N-L-P-A-C-Q-V-V-V-S-P-K-G-G-T-L-P-N-F-G-K-L-S-A-D-L-L-K-H-I-P-E-A-L-P-L-V-T-S-S-K"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-R-V-S-T-S-E-F-R-V-G-L-R-V-E-I-D-G-Q-P-Y-V-I-L-Q-N-D-F-V-K-P-G-K-G-Q-A-F-N-R-I-K-V-K-N-F-L-T-G-R-V-I-E-K-T-F-K-S-G-E-S-I-E-T-A-D-V-R-E-Q-Q-M-R-L-L-Y-T-D-Q-E-G-A-T-F-M-D-D-E-T-F-E-Q-E-L-I-F-W-D-K-L-E-N-I-R-Q-W-L-L-E-D-T-V-Y-T-L-V-R-Y-N-G-D-V-I-S-V-E-P-P-I-F-M-E-L-S-I-A-E-T-A-P-G-V-R-G-D-T-A-S-G-R-V-L-K-P-A-T-T-N-T-G-A-K-I-M-V-P-I-F-I-E-E-G-E-V-V-K-V-D-T-R-T-G-S-Y-E-S-R-V-S-K"} +{"text": "### FUNCTION Might have a role analogous to that of eukaryotic histone proteins ### SEQUENCE -M-A-L-K-D-T-A-K-K-M-T-D-L-L-E-S-I-Q-Q-N-L-L-K-A-E-K-G-N-K-A-A-A-Q-R-V-R-T-E-S-I-K-L-E-K-I-A-K-V-Y-R-K-E-S-I-K-A-E-K-M-G-L-M-K-R-S-K-V-A-A-K-K-A-K-A-A-A-K-K-P-A-K-A-T-K-V-V-T-K-K-A-C-T-K-K-T-C-A-T-K-A-K-A-K-P-V-K-K-A-A-T-K-T-K-A-K-V-T-K-K-V-R-S-T-K-K"} +{"text": "### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-F-S-R-V-L-F-S-I-L-F-F-L-G-C-C-P-S-L-F-A-D-V-D-S-P-Q-R-A-T-F-G-Q-P-A-V-M-L-G-I-A-I-V-F-F-Y-F-I-L-W-R-P-E-Q-K-R-R-Q-A-M-E-K-R-K-S-E-L-A-V-G-D-K-V-T-A-M-G-I-V-G-T-I-A-E-I-R-E-H-T-V-V-L-N-I-A-S-G-K-I-E-I-L-K-A-A-I-S-E-I-F-K-A-E-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-L-L-K-G-L-P-V-A-K-D-V-R-V-A-I-V-G-A-C-F-N-A-P-I-A-D-R-L-V-S-G-A-R-E-T-F-F-E-S-G-G-S-P-D-S-L-T-V-V-R-V-P-G-A-F-E-I-P-C-A-I-K-K-M-L-S-K-G-N-L-F-Q-A-I-V-A-C-G-V-L-I-Q-G-E-T-S-H-Y-E-H-I-A-D-N-V-A-A-G-I-A-R-L-S-V-E-F-C-L-P-I-T-F-S-V-I-T-A-P-N-V-E-A-A-W-E-R-A-G-I-K-G-P-N-L-G-A-S-G-M-R-T-A-L-E-M-A-S-L-F-S-L-I-E-K-E"} +{"text": "### FUNCTION A probable RNA-binding protein ### SEQUENCE -M-K-E-F-L-A-Y-I-V-K-N-L-V-D-R-P-E-E-V-H-L-K-E-V-Q-G-T-N-T-I-I-Y-E-L-T-V-A-K-G-D-I-G-K-I-I-G-K-E-G-R-T-I-K-A-I-R-T-L-L-V-S-V-A-S-R-D-N-V-K-V-S-L-E-I-M-E-E-R"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-Q-K-F-I-I-H-K-G-I-A-C-P-L-E-Y-A-N-I-D-T-D-Q-I-I-P-K-Q-F-L-L-A-V-S-K-Q-G-F-G-K-H-L-F-H-D-L-R-Y-L-D-D-K-E-S-V-L-N-M-D-F-N-L-N-K-K-E-Y-Q-N-S-S-I-L-V-S-F-E-N-F-G-S-G-S-S-R-E-H-A-P-W-A-L-V-D-Y-G-I-R-A-I-I-A-P-S-F-A-D-I-F-K-N-N-A-L-G-N-G-L-L-T-I-E-L-A-K-D-E-V-L-E-I-V-D-E-L-K-K-S-Q-D-K-N-I-E-I-S-L-L-E-K-R-V-F-F-K-D-K-I-F-S-F-D-L-D-D-F-H-R-I-C-L-L-E-G-L-D-N-I-A-L-T-L-K-H-E-A-Q-I-K-A-Y-E-K-N-S-K-S-F-L-V"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-E-R-I-R-L-K-L-K-A-Y-D-H-R-V-L-D-R-T-V-A-A-I-V-E-A-V-K-R-T-G-A-D-I-R-G-P-I-P-M-P-T-K-I-K-R-Y-T-V-L-K-S-P-H-I-N-K-D-S-R-E-Q-F-E-I-R-I-H-A-R-M-L-D-I-V-A-A-T-P-D-T-V-D-S-L-T-K-L-D-L-A-P-E-V-S-V-E-V-R-A-M-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-E-Y-I-V-E-K-I-G-M-S-R-T-I-T-N-P-S-I-A-V-T-L-L-R-V-V-N-A-K-V-C-E-V-E-G-G-K-A-L-V-A-Y-P-K-G-K-A-S-N-K-C-V-A-G-Q-Q-K-K-Y-N-L-S-A-E-Y-N-R-F-A-T-L-E-V-A-N-T-E-A-G-D-L-D-E-T-P-L-N-E-A-K-I-L-K-V-S-F-N-T-K-G-R-G-Y-S-G-V-M-K-R-H-N-F-A-G-G-P-A-S-H-G-S-R-F-H-R-R-H-G-S-I-G-N-R-E-W-P-G-R-V-Q-P-G-M-K-M-A-G-H-Y-G-N-T-K-V-T-I-K-N-E-V-V-S-Y-D-A-E-N-K-I-L-V-V-K-G-A-V-P-G-Y-N-G-A-M-G-K-I-R-I-A-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-V-D-D-H-V-M-K-K-V-I-A-A-K-K-A-N-D-N-K-P-I-K-T-W-S-R-R-S-T-I-T-P-D-M-I-G-L-T-F-N-V-H-N-G-K-S-F-I-P-V-Y-I-T-E-N-H-I-G-Y-K-L-G-E-F-A-P-T-R-T-F-K-G-H-K-G-S-V-Q-K-K-I-G-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-K-A-L-I-K-F-I-R-L-S-P-T-K-A-R-L-I-A-R-E-V-Q-G-M-N-A-E-L-A-M-A-S-L-K-F-M-P-N-K-G-A-K-Y-I-A-N-A-I-S-S-A-V-A-N-G-G-F-E-A-N-E-V-I-V-K-S-C-R-V-D-A-A-A-V-L-K-R-F-R-P-R-A-R-G-S-A-S-R-I-R-K-P-T-S-H-I-L-V-E-V-A-K-A-E-V-K-S-E-E-K-K-T-V-A-K-K-T-T-T-T-K-A-P-A-K-K-T-T-S-T-K-K-A-T-V-K-K-E-S"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-Y-R-K-M-M-K-G-R-N-R-G-Y-A-N-R-G-T-E-F-T-F-G-E-F-A-L-K-A-T-E-A-G-R-I-N-S-R-Q-I-E-A-A-R-I-A-L-T-R-F-V-K-R-Q-G-K-T-W-I-R-V-F-P-D-K-P-L-T-K-K-P-L-E-T-R-M-G-K-G-K-G-A-V-E-E-W-V-M-N-I-K-P-G-R-I-I-Y-E-M-A-G-V-S-E-E-M-A-R-E-A-L-T-L-A-M-H-K-L-P-F-K-T-K-F-V-T-R-E-S-Q-N-E-I-Y"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-F-K-R-E-I-Q-G-V-V-V-K-I-A-G-E-K-T-A-S-V-L-V-E-R-K-V-V-H-P-R-Y-R-K-I-V-K-R-F-K-K-Y-L-I-H-D-E-R-N-E-V-K-V-G-D-T-V-V-A-V-E-C-R-P-L-S-K-R-K-S-F-R-L-K-S-V-L-A-T-G-V-E"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-V-K-L-K-I-K-K-G-D-S-V-K-V-I-T-G-D-D-K-G-K-T-G-K-V-L-A-V-Y-P-K-T-L-K-V-V-V-E-G-C-K-I-A-K-K-A-I-K-P-S-E-K-N-P-N-G-G-F-I-N-K-E-M-P-M-D-I-S-N-V-A-K-V-Q-E"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-M-R-L-K-E-K-Y-N-Q-S-I-K-P-A-L-V-K-E-F-D-I-K-N-P-M-L-I-P-V-I-E-K-V-V-I-S-V-G-A-G-E-L-A-K-D-Q-K-V-L-Q-N-V-A-D-T-I-S-L-I-A-G-Q-K-A-V-I-T-K-A-K-K-S-V-A-G-F-K-V-R-E-G-F-P-V-G-V-M-V-T-L-R-K-E-N-M-Y-A-F-L-D-K-L-I-S-I-A-L-P-R-V-K-D-F-R-G-L-S-R-D-G-F-D-G-R-G-N-Y-N-F-G-L-D-E-Q-L-M-F-P-E-V-E-Y-D-K-I-L-R-T-H-G-M-N-I-S-I-V-T-T-A-Q-N-D-K-Q-A-Q-K-L-L-E-L-I-G-V-P-F-T-K-G-K"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-A-A-R-K-P-K-F-K-V-R-A-Y-T-R-C-Q-I-C-G-R-P-H-S-V-Y-R-D-F-G-I-C-R-V-C-L-R-K-M-G-N-E-G-L-I-P-G-L-K-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-I-N-D-I-I-S-D-S-L-T-R-I-R-N-A-G-M-R-K-L-E-T-T-K-L-L-H-S-K-V-V-E-A-L-V-G-I-F-Q-A-K-G-Y-I-E-S-F-N-V-I-E-E-D-K-K-K-F-I-N-V-V-L-K-Y-D-E-K-G-K-S-V-I-N-E-L-K-R-I-S-K-P-G-R-R-V-Y-K-G-K-D-E-I-K-R-F-K-N-G-Y-G-T-I-V-V-S-T-S-H-G-V-L-A-N-D-E-A-Y-K-A-G-V-G-G-E-I-L-C-T-I-W"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-R-A-N-V-L-K-R-K-L-T-L-R-I-K-R-K-K-R-I-R-A-K-I-S-G-C-E-N-F-P-R-I-S-V-F-K-S-N-R-T-L-Y-I-Q-A-I-D-D-V-K-A-V-T-L-A-A-V-D-G-R-K-L-G-V-K-A-N-K-E-G-A-K-K-I-A-A-E-F-A-K-T-L-K-V-K-K-I-E-Q-A-V-F-D-R-N-G-Y-V-Y-H-G-V-I-A-A-L-A-E-S-L-R-E-N-G-I-R-L"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-E-K-Y-N-R-E-E-F-E-E-V-I-V-D-I-G-R-V-T-K-V-V-K-G-G-R-R-F-R-F-T-A-L-V-I-V-G-N-R-K-G-L-V-G-V-G-Y-G-K-A-K-E-V-P-D-A-I-R-K-A-V-D-D-A-F-K-N-I-V-E-V-K-T-K-G-S-T-I-A-H-D-V-E-V-K-Y-N-A-S-R-I-L-L-K-P-A-S-E-G-T-G-V-I-A-G-G-S-T-R-P-I-V-E-L-A-G-I-K-D-I-L-T-K-S-L-G-S-N-N-S-A-N-V-V-R-A-T-I-K-A-L-T-M-L-K-G"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-D-F-S-K-M-G-E-L-L-N-Q-V-Q-E-K-A-K-N-I-E-L-E-L-A-N-R-E-F-S-A-K-S-G-A-G-L-V-K-V-S-A-N-G-K-G-E-I-I-D-V-S-I-D-D-S-L-L-E-D-K-E-S-L-Q-I-L-L-I-S-A-I-N-D-V-L-A-M-V-A-Q-N-R-S-S-M-A-N-D-V-L-G-G-F-G-G-M-K-L"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-K-S-A-E-K-R-A-R-Q-T-I-K-K-T-E-R-N-R-F-Y-R-T-R-L-K-N-I-T-K-A-V-R-E-A-A-A-N-G-N-K-N-A-A-N-E-A-L-K-V-A-N-K-S-I-H-A-M-V-S-R-G-F-I-K-K-Q-T-A-S-R-R-V-S-R-L-A-L-L-V-N-K-I-A"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-R-K-I-V-K-K-K-V-V-K-K-N-I-A-K-G-I-V-Y-I-S-A-T-F-N-N-T-M-V-T-V-T-D-E-M-G-N-A-I-A-W-S-S-A-G-G-L-G-F-K-G-S-K-K-S-T-P-Y-A-A-Q-Q-A-V-E-D-A-L-N-K-A-K-E-H-G-I-K-E-V-G-I-K-V-Q-G-P-G-S-G-R-E-T-A-V-K-S-V-G-A-M-E-G-I-K-V-T-F-L-K-D-I-T-P-L-A-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-L-P-K-K-K-R-I-E-Y-G-L-T-Y-I-Y-G-I-G-L-F-T-S-R-K-I-L-D-K-V-G-I-S-Y-D-K-R-V-H-E-L-S-E-D-E-A-A-A-I-R-K-E-I-Q-E-N-Y-M-V-E-G-D-L-R-K-Q-V-A-M-D-I-K-A-L-M-D-L-G-S-F-R-G-L-R-H-R-K-G-L-P-V-R-G-Q-K-T-K-T-N-A-R-T-R-K-G-K-R-K-T-V-G-A-K-S"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-E-I-D-G-T-V-L-E-A-L-P-N-A-N-F-K-V-E-L-D-N-K-H-V-I-L-C-H-I-A-G-K-M-R-M-H-Y-I-R-I-M-P-G-D-K-V-K-V-E-L-T-P-Y-S-L-D-K-G-R-I-T-F-R-Y-K"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-R-V-G-C-D-I-I-A-I-S-R-I-E-K-I-H-S-R-H-G-K-N-F-L-D-K-F-L-N-P-K-E-Q-I-L-I-K-N-P-A-T-L-A-G-L-W-A-A-K-E-A-A-S-K-A-L-G-V-G-I-C-E-L-C-S-F-F-D-I-E-I-S-K-D-E-K-N-A-P-K-L-K-Y-S-Q-K-I-T-K-D-F-N-I-T-Q-T-S-L-S-I-S-H-D-N-G-F-A-I-A-I-V-A-V-V"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-K-I-A-L-F-G-G-S-F-D-P-P-H-N-G-H-N-S-V-V-L-E-A-L-E-K-L-D-I-D-K-L-I-I-M-P-T-Y-I-N-P-F-K-Q-S-F-S-A-D-E-K-Q-R-F-L-W-V-K-K-L-W-G-H-L-P-K-V-E-I-C-D-F-E-I-R-Q-K-R-P-V-P-S-I-E-S-V-K-Y-L-Y-K-L-Y-N-P-S-K-F-Y-L-L-I-G-A-D-H-L-E-K-L-H-L-W-H-D-F-E-K-L-N-S-L-V-E-F-V-I-A-N-R-N-D-I-G-I-P-K-N-F-K-D-L-K-T-N-K-K-I-A-S-S-F-I-R-D-T-L-N-T-N-E-V-C-E-E-I-K-D-E-V-K-K-Y-Y-E-K-L-Q-K-N"} +{"text": "### FUNCTION Might be involved in Fe ### SEQUENCE -M-T-L-N-E-L-K-D-G-Q-K-A-I-I-V-N-L-N-A-H-K-E-L-K-N-R-L-L-S-F-G-F-I-K-N-K-N-L-K-K-I-H-S-S-L-K-N-A-T-I-M-V-E-L-D-T-S-C-V-I-L-R-S-D-E-A-K-T-I-E-V-N-L-I"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-D-K-R-I-E-E-V-A-A-K-A-L-E-K-M-G-N-D-R-Y-R-L-S-L-V-V-A-K-R-A-E-Q-L-A-N-G-A-T-P-L-V-D-F-D-K-N-K-N-K-L-A-D-I-A-L-Y-E-I-A-E-N-K-I-T-L-E-G-L-V-E-T-N-R"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-V-K-G-L-E-K-F-N-E-L-V-E-S-F-A-N-L-P-T-I-G-K-K-T-A-I-R-L-A-Y-H-L-C-I-N-N-Q-I-D-G-M-K-L-A-H-N-I-E-N-A-I-R-F-I-K-P-C-E-Q-C-G-A-L-S-E-N-E-L-C-E-I-C-S-D-K-E-R-N-K-N-I-L-C-I-V-E-S-P-K-D-I-L-T-L-E-E-S-Q-S-Y-N-G-L-Y-F-V-L-D-E-L-N-E-E-K-L-E-K-L-K-Q-I-I-L-K-L-N-I-S-E-L-I-F-A-L-T-H-S-I-N-S-D-A-T-I-F-F-I-E-D-K-F-K-G-L-N-L-T-F-S-K-I-A-Q-G-I-P-S-G-V-N-L-E-N-V-D-L-I-S-L-N-K-A-M-N-F-R-T-K-I"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-W-S-S-P-S-H-W-L-I-I-L-L-I-V-V-L-L-F-G-A-K-K-I-P-E-L-A-K-G-L-G-K-G-I-K-T-F-K-D-E-M-N-N-D-D-E-V-A-K-N-T-Q-K-I-E-E-N-K-N-T-T-N-N-T-N-A-D-A-S-I-D-E-T-K-K-A"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-P-K-T-Q-T-L-E-Q-T-K-L-S-E-P-K-M-Y-K-V-I-L-L-N-D-D-V-T-T-M-D-F-V-I-E-I-L-M-N-I-F-H-Q-N-L-E-K-A-S-Q-T-M-L-E-I-H-H-N-G-S-G-I-C-G-I-Y-T-Q-E-I-A-L-S-K-Q-K-K-V-M-D-A-A-K-L-A-N-F-P-L-Q-A-K-V-E-E-E"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-I-I-A-R-N-K-K-A-L-F-D-Y-S-I-I-E-R-F-E-A-G-I-V-L-K-G-S-E-V-V-A-L-R-A-G-R-A-N-L-K-D-S-F-V-R-I-I-K-N-E-I-F-L-L-N-S-H-I-S-L-L-H-T-T-H-S-F-Y-K-H-E-E-R-G-A-R-K-L-L-M-H-R-K-Q-I-D-K-L-L-G-K-V-S-I-E-G-Y-T-I-V-A-L-D-L-Y-F-N-T-K-N-K-V-K-A-T-L-A-L-A-K-G-K-N-L-H-D-K-R-E-T-L-K-K-K-Q-A-D-L-E-A-R-A-A-M-K-N-Y-K"} +{"text": "### FUNCTION Specifically methylates the N7 position of guanine in position 527 of 16S rRNA ### SEQUENCE -M-I-F-K-D-Y-D-F-L-Q-N-Y-D-L-K-N-F-E-E-K-V-K-I-Y-K-E-L-L-S-K-F-N-R-I-H-N-L-T-H-L-K-N-I-D-E-N-I-F-D-S-I-K-I-L-D-F-Y-D-F-S-K-A-K-N-I-A-D-I-G-S-G-A-G-F-P-V-V-F-L-A-F-L-L-Q-S-N-F-H-L-F-E-P-N-P-K-K-A-A-F-L-R-T-L-K-I-E-C-E-L-P-N-L-H-I-Y-K-E-K-V-Q-E-Y-K-N-T-F-K-A-D-I-I-T-S-R-A-L-M-D-V-K-P-L-L-E-I-C-K-N-L-K-D-E-N-T-V-F-I-L-W-K-G-S-E-I-Y-Q-E-L-E-N-I-K-D-Y-E-I-F-E-N-N-L-R-R-Y-C-I-L-K"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-N-F-D-K-F-S-T-N-E-E-F-S-S-V-Y-K-V-G-K-K-W-H-C-E-G-V-I-I-F-Y-L-N-S-Y-E-K-K-I-A-V-V-A-S-K-K-V-G-K-A-V-V-R-N-R-S-K-R-I-L-R-A-L-F-A-K-F-E-R-Y-L-Q-D-G-K-Y-I-F-V-A-K-N-E-I-T-E-L-S-F-S-R-L-E-K-N-L-K-W-G-L-K-K-L-E-C-F-K"} +{"text": "### FUNCTION Participates in the translocation of lipoproteins from the inner membrane to the outer membrane Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate ### SEQUENCE -M-K-K-T-F-L-I-F-F-I-F-I-G-Q-L-F-A-L-D-L-N-F-N-T-F-S-S-N-F-T-Q-I-V-K-S-K-N-S-T-L-S-Y-S-G-H-F-I-L-S-K-D-Q-A-Y-W-S-Y-D-T-P-S-K-K-E-I-Y-I-N-K-N-Q-V-T-I-V-E-H-D-L-E-Q-V-I-F-S-H-L-D-N-I-P-N-L-N-E-I-F-K-K-A-S-L-I-D-K-D-K-L-V-A-K-Y-D-N-I-N-Y-T-I-K-L-N-Q-E-Q-I-Q-S-I-S-Y-K-D-E-F-E-N-D-V-I-I-N-L-N-N-Q-I-K-N-P-K-I-N-S-D-V-F-K-A-K-I-P-Q-N-Y-D-I-V-R"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-I-K-L-T-Q-E-E-Q-K-Y-L-L-D-S-I-R-I-I-P-D-F-P-K-K-G-I-I-F-R-D-I-T-T-L-L-N-N-K-E-A-L-N-F-L-L-K-H-L-K-E-R-Y-K-D-Y-N-L-D-F-I-A-G-T-E-S-R-G-F-I-F-A-S-M-I-C-A-K-L-N-L-P-F-V-P-I-R-K-P-G-K-L-P-F-E-T-F-S-C-E-Y-D-L-E-Y-G-S-D-K-V-E-L-H-K-D-A-F-K-N-I-Q-N-A-R-V-L-L-V-D-D-L-I-A-T-G-G-T-A-I-A-S-Y-E-L-I-Q-K-A-G-A-K-C-V-E-A-C-F-L-I-N-L-K-D-L-N-G-A-N-K-L-E-K-L-T-S-V-Y-S-V-L-E-I"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-V-V-G-I-E-G-I-I-T-K-K-E-P-T-F-I-I-V-K-C-A-S-G-L-S-Y-G-I-F-I-S-L-F-C-S-A-K-I-Q-T-Q-E-K-H-E-F-F-I-T-Q-I-I-K-E-D-S-N-K-F-Y-G-F-L-D-K-D-E-Q-K-M-F-E-M-L-L-K-V-N-G-V-G-A-N-T-A-M-A-V-C-S-S-L-D-V-N-S-F-Y-K-A-L-S-L-G-D-E-S-V-L-K-K-V-P-G-I-G-P-K-S-A-K-R-I-I-V-E-L-S-D-T-K-T-K-L-E-N-V-S-D-D-K-S-E-A-L-A-A-L-L-T-L-G-F-K-Q-E-K-I-I-S-V-L-V-S-A-Q-A-T-G-T-S-E-L-I-K-E-A-L-K-K-L-G"} +{"text": "### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-K-V-L-L-G-I-S-G-S-S-S-V-N-L-G-L-K-L-L-K-N-L-E-N-Q-C-E-L-Y-C-I-L-T-Q-G-A-K-L-N-F-K-T-E-N-Q-A-N-L-E-E-I-C-Q-E-N-F-K-Y-T-H-F-L-D-D-K-N-L-S-L-S-V-A-S-G-S-F-G-I-E-K-T-I-I-A-P-C-S-I-S-S-L-A-K-I-H-A-G-F-A-D-T-L-L-M-R-A-A-A-V-A-L-K-E-R-K-K-L-I-L-G-V-R-E-M-P-F-S-T-L-N-L-E-H-M-L-K-L-S-Q-M-G-V-I-I-A-P-P-I-I-A-S-Y-S-K-A-N-N-L-E-Q-M-E-N-F-I-A-G-K-W-L-D-L-L-E-I-K-H-N-L-Y-E-K-W-Q-N-F"} +{"text": "### FUNCTION Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis ### SEQUENCE -M-Y-V-V-F-E-G-I-D-C-V-G-K-S-T-Q-I-S-L-L-K-E-I-Y-K-D-A-I-F-T-L-E-P-G-G-T-E-L-G-K-H-L-R-E-I-L-L-N-K-T-H-P-I-N-K-R-A-E-L-L-L-F-L-A-D-R-A-Q-H-F-E-E-I-L-K-T-N-Q-N-K-L-I-I-S-D-R-S-F-I-S-G-M-A-Y-A-K-D-F-E-N-D-L-L-F-A-L-N-S-F-A-L-E-N-F-F-P-Q-K-I-I-F-L-K-G-D-A-N-L-I-Q-E-R-L-S-Q-K-E-L-D-S-I-E-K-R-G-I-E-Y-F-L-S-V-Q-D-K-L-E-K-V-L-H-F-L-K-E-K-I-S-V-E-I-L-T-L-D-A-K-E-S-K-E-K-L-H-Q-Q-I-K-E-F-L-Q"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-K-N-K-Y-I-E-Q-F-E-A-K-Q-I-E-G-K-N-V-P-D-F-R-A-G-D-T-L-K-L-A-I-R-I-K-E-G-D-K-T-R-I-Q-N-F-E-G-I-C-I-A-R-R-G-N-G-V-S-E-T-F-I-V-R-K-I-G-A-N-N-V-G-V-E-R-I-F-P-I-Y-S-E-S-L-E-S-I-T-V-L-R-R-G-R-V-R-R-A-R-L-F-Y-L-R-D-R-R-G-K-A-A-R-I-K-E-L-K-K"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-E-K-D-F-V-Q-V-A-K-L-G-K-T-V-G-L-K-G-Y-V-K-L-H-N-L-S-D-F-S-S-Q-F-K-K-D-A-T-F-F-I-K-N-T-K-E-M-L-K-I-K-H-Y-N-A-N-N-S-T-V-L-F-E-N-Y-E-D-I-E-K-A-K-E-L-T-N-L-I-L-F-Q-S-I-E-K-S-R-Q-T-C-K-L-K-K-D-E-F-F-Y-F-D-I-L-E-C-E-V-F-E-E-D-K-R-L-G-K-V-V-D-I-L-E-T-G-A-S-Y-L-F-E-I-Q-S-D-E-K-W-V-E-K-K-Y-P-K-I-F-F-I-P-Y-L-D-K-F-V-K-N-I-D-I-E-K-R-Q-I-F-C-T-Q-D-A-F-L-I-L-E-N-S"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-A-N-F-I-S-L-K-K-N-E-D-I-L-D-T-I-K-K-Q-Q-K-I-H-S-N-Q-I-V-V-Y-F-R-K-T-N-L-K-N-V-R-L-A-I-S-I-S-K-K-K-F-K-L-A-T-Q-R-N-R-I-R-R-L-I-K-A-W-F-I-A-A-D-I-P-I-K-S-Y-D-I-V-V-L-V-K-P-S-F-I-D-G-S-F-V-L-N-C-N-N-L-K-I-I-L-Q-R-I-I-N-K-E-K-R"} +{"text": "### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-S-R-Q-L-V-D-I-A-Y-N-A-I-K-N-N-K-I-Y-N-K-K-P-F-T-F-D-D-I-I-N-E-I-V-K-N-S-N-V-N-L-V-E-V-N-S-Q-L-G-V-L-Y-T-T-L-I-Q-D-T-R-F-I-S-I-G-D-L-E-W-N-L-R-E-R-L-S-L-D-E-I-T-K-I-N-N-A-M-Y-E-V-G-L-Y-K-D-S-D-R-E-E-D-E-H-E-I-V-K-N-D-K-L-T-Q-S-K-E-Q-E-E-S-D-E-V-S-S-L-S-D-F-V-G-Y-E-D-E-D-E-E-F-K-N-N-N-T-S-N-K-D-E-I-E-D-E-E-E-L-E-E-E-E"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-Q-K-S-S-M-L-K-K-E-V-A-I-A-R-R-Q-W-Y-L-V-D-A-T-D-L-V-L-G-R-L-S-V-K-V-A-D-I-L-R-G-K-N-K-V-D-Y-T-P-N-V-D-A-G-D-Y-V-V-V-I-N-S-D-K-V-V-L-T-G-Q-K-A-L-R-E-N-W-Y-N-H-S-H-Y-I-G-G-L-R-T-R-S-G-E-E-M-I-S-K-Y-S-D-E-L-I-R-R-S-V-K-G-M-L-P-K-N-K-L-A-K-Q-I-L-N-K-L-F-I-Y-K-N-D-K-H-P-H-E-A-Q-Q-P-T-I-L-E-L-K-L-K"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-A-L-F-K-I-N-K-G-E-I-M-N-F-V-N-S-T-Q-L-K-T-D-I-P-N-F-D-S-G-D-T-I-I-V-H-N-R-I-V-E-G-K-K-S-R-I-Q-K-F-E-G-V-V-L-R-R-R-G-S-G-S-S-E-T-V-I-V-R-K-E-S-S-G-I-G-V-E-Q-S-F-N-I-H-S-P-L-V-E-K-I-E-V-I-K-Y-G-K-V-R-R-A-Y-I-S-Y-M-R-N-R-S-G-K-S-A-R-I-K-E-L-N-K-Q"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-K-Y-E-I-M-L-V-V-R-G-D-L-D-Q-E-Q-A-N-K-V-A-N-E-L-K-A-T-L-K-N-T-E-V-K-E-N-N-Y-D-G-V-Q-Q-L-A-Y-E-I-N-K-L-K-T-A-Y-R-Y-V-Y-N-F-E-T-T-D-V-S-L-I-N-E-F-R-R-L-A-I-I-N-K-N-V-L-R-H-I-I-I-N-L-E-K-D-Y-G-Y-K-A-T-V-N-T-K-K-V-Q-R-N-E-K-R-A-E-V-Y-A-R-Q-K-E-E-A-E-R-R-A-V-E-R-Q-A-A-Y-E-A-M-K-A-E-R-E-A-A-G-L-P-V-K-E-F-V-K-N-T-N-S-K-R"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-K-V-T-N-N-R-N-R-K-P-R-K-K-V-C-I-L-S-A-K-G-I-E-H-V-D-Y-K-D-V-E-L-L-Q-R-F-I-N-N-N-N-K-I-A-S-R-R-V-T-G-A-S-A-R-M-Q-R-R-I-A-N-A-I-K-R-A-R-F-V-G-L-L-P-Y-V-K-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-L-E-D-I-A-S-L-G-K-K-N-E-I-I-D-V-S-D-G-Y-A-K-N-F-L-I-R-Q-K-K-A-V-A-L-T-N-K-S-Q-E-V-L-N-K-D-L-A-I-L-E-A-Q-E-Q-Q-A-I-L-D-A-T-L-L-K-D-K-L-E-Q-K-P-L-Q-F-F-L-K-T-N-N-L-Q-T-F-G-S-I-S-N-K-Q-I-I-D-E-I-N-K-E-Q-K-F-I-T-K-H-M-I-T-K-P-H-A-L-G-I-G-E-H-I-V-E-I-L-L-H-K-K-V-T-A-K-L-H-V-I-V-S-K-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-P-K-K-K-E-V-T-R-I-A-K-L-N-L-I-G-G-Q-A-K-P-G-P-A-L-A-S-V-G-I-N-M-A-E-F-T-K-S-F-N-D-K-T-K-D-Q-N-G-K-V-I-P-V-I-I-T-A-Y-K-D-K-S-F-D-Y-V-I-K-T-T-P-V-T-F-L-L-K-D-I-A-K-I-K-S-G-A-K-D-P-K-K-Q-T-V-A-T-I-S-K-E-Q-A-L-E-I-A-R-Y-K-L-I-D-M-T-A-Y-D-E-E-A-A-L-R-M-I-A-G-S-A-K-Q-M-G-I-V-I-E-G-V-S-A-Y-K-E-K-K-G-N"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-L-K-P-Q-K-R-Q-V-L-A-D-P-V-Y-N-S-R-L-V-T-K-L-I-N-A-I-M-Y-D-G-K-K-G-L-A-Q-S-I-I-Y-S-A-F-E-I-V-E-Q-K-T-G-K-P-A-L-E-V-F-N-K-A-I-D-N-V-M-P-I-I-E-L-K-V-R-R-V-G-G-S-N-F-Q-V-P-T-E-V-T-P-E-R-R-Q-T-L-G-L-R-W-I-T-L-Y-A-R-L-R-H-E-H-T-M-I-E-K-L-A-H-E-I-I-D-A-S-N-N-V-G-A-A-I-K-K-K-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-L-R-W"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-N-F-K-I-Y-E-T-K-I-R-E-E-F-E-L-V-L-K-W-M-H-N-E-F-I-K-L-R-T-G-R-A-T-P-A-I-L-D-G-I-L-V-N-Y-Y-G-S-M-M-P-I-N-Q-L-A-N-I-S-V-P-E-P-R-V-L-A-I-K-P-Y-D-R-S-S-I-K-D-I-A-T-A-I-N-A-S-N-L-G-V-N-P-Q-V-D-V-D-I-I-R-L-T-F-A-A-P-T-E-E-V-R-K-N-L-V-K-K-A-K-Q-V-G-E-E-A-K-I-R-V-R-H-I-R-Q-E-A-Q-D-L-F-K-K-D-S-T-T-I-E-D-D-K-K-F-F-Q-T-E-L-D-N-L-T-K-E-L-N-K-E-I-E-T-V-V-S-H-K-E-K-D-I-M-T-V"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-I-N-I-K-D-L-I-M-K-I-A-K-E-N-K-I-A-L-N-M-D-N-L-N-I-E-L-K-S-L-G-I-D-S-L-S-A-M-N-L-I-M-K-I-E-D-Q-I-G-V-Q-L-P-D-E-K-L-L-K-I-K-N-L-R-D-L-I-N-A-F-E-D-V-L-K"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-H-F-L-I-T-N-E-V-K-K-I-F-N-D-K-L-Y-S-Q-R-F-K-Q-I-T-D-L-V-S-T-K-L-N-I-D-K-K-R-F-F-E-C-H-F-V-D-E-K-T-I-Q-E-I-N-K-N-Y-R-N-K-D-Y-I-T-D-V-I-S-F-A-F-D-D-G-E-I-I-T-P-L-L-G-E-M-Y-I-C-Y-Q-K-V-V-D-Q-A-S-Q-F-A-H-S-F-E-R-E-L-C-F-L-F-T-H-G-L-L-H-L-L-G-Y-D-H-I-K-I-E-D-E-K-I-M-F-A-L-Q-D-E-I-L-N-E-L-K-I-T-R-N-I-N-G-A-R-N-D"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-I-N-I-D-Y-I-K-S-K-I-R-D-V-P-D-F-P-K-K-G-I-V-F-K-D-I-T-P-L-F-L-E-P-K-I-I-E-K-I-V-D-D-F-A-D-F-A-K-S-L-N-I-D-A-I-I-G-A-E-S-R-G-F-L-F-A-A-P-L-S-I-K-L-N-K-P-F-I-L-V-R-K-P-N-K-L-P-N-D-V-Y-S-A-E-Y-T-L-E-Y-G-S-S-R-V-E-M-H-K-D-A-L-K-P-N-Q-R-V-L-I-V-D-D-L-L-A-T-G-G-T-V-A-A-I-E-N-L-V-R-Q-A-K-G-I-V-A-G-S-V-Y-L-I-R-L-G-F-L-K-G-E-E-K-L-S-G-K-V-H-A-L-I-N-Y"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-Y-N-I-K-F-L-D-L-L-N-S-N-L-K-P-N-P-Q-W-I-F-K-D-P-H-P-I-L-R-E-V-T-Q-D-I-E-G-N-E-L-S-K-D-D-I-Y-Y-L-K-K-M-V-R-Y-I-D-V-C-Y-H-N-Q-A-K-K-Y-K-I-R-S-G-I-A-I-A-A-N-Q-V-G-W-N-K-R-A-T-Y-I-H-F-N-D-E-A-K-E-H-H-Y-L-L-I-N-P-H-I-I-K-R-S-S-E-I-A-Y-L-N-P-G-E-G-C-L-S-V-D-D-D-R-S-G-Y-V-I-R-N-K-K-V-H-V-K-A-Y-D-L-I-S-E-Q-F-I-D-Q-E-F-S-G-I-I-A-I-C-I-Q-H-E-I-G-H-L-D-A-G-L-Y-Y-D-N-I-N-Q-Q-Q-P-F-Y-A-D-P-S-W-T-K-I-G-R"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-N-Y-L-I-F-K-V-I-Y-A-N-A-N-I-V-V-G-E-H-N-F-I-G-Y-Q-I-R-I-P-K-D-Y-E-L-E-I-N-K-F-C-K-L-Y-L-Y-E-Y-I-S-I-M-P-N-K-N-L-I-I-K-D-L-Y-G-F-R-T-Y-N-E-R-L-L-F-I-D-L-I-S-I-N-S-I-G-P-K-T-A-I-N-I-L-K-Y-D-I-D-T-I-I-D-A-I-A-T-K-N-I-D-Y-L-I-T-I-K-G-I-N-Q-R-N-A-N-L-I-C-D-Q-L-N-Y-K-Y-I-N-K-V-N-D-K-N-N-W-A-K-E-L-S-I-G-L-E-N-L-G-Y-T-K-K-D-I-E-Y-A-I-T-K-V-K-I-N-S-Q-Q-D-I-D-I-S-E-I-I-S-S-A-I-K-E-I-S-L-R-H-E-N"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-K-L-V-H-G-I-D-I-I-E-W-N-R-E-E-L-N-N-P-L-F-A-K-R-I-L-I-D-N-E-L-E-Y-Y-F-Q-L-N-S-S-R-E-K-K-R-Y-L-A-S-V-F-A-C-K-E-A-V-M-K-A-L-K-L-K-Y-G-Y-G-D-I-L-I-L-K-T-E-N-Q-R-Q-V-Y-L-N-K-I-L-I-K-E-L-E-L-S-I-S-Y-T-E-T-Y-I-V-A-S-V-V-G-L-I-N-N-M-N"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-K-L-A-L-D-L-G-T-K-S-C-G-F-A-I-S-D-L-L-G-I-I-A-S-G-L-D-N-F-I-Y-E-E-N-D-F-T-A-V-L-A-K-I-D-E-I-M-I-N-Y-H-H-E-I-D-T-I-V-L-G-Y-P-T-N-V-Y-D-G-S-K-N-E-R-T-Y-L-I-E-S-F-Y-A-L-L-K-Q-H-F-L-N-H-E-K-I-K-I-V-Y-E-D-E-R-F-S-T-K-I-A-T-Q-R-L-K-N-S-C-V-K-A-A-K-I-K-K-V-K-D-K-M-S-A-V-V-I-L-E-S-Y-L-S-K-N-H-F-N"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-N-E-V-R-V-A-R-L-E-S-L-I-K-D-V-I-N-N-A-L-A-N-E-I-N-D-K-I-A-K-L-A-R-V-T-A-V-R-L-S-N-D-L-S-V-A-K-I-F-L-D-A-H-K-R-E-S-M-L-K-V-L-E-N-V-N-K-V-S-G-L-L-R-S-K-L-A-A-E-W-T-S-Y-K-V-P-E-L-R-F-V-I-D-E-T-I-D-Y-A-N-H-I-D-E-L-F-K-K-I-K-Q-Q-E-N"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-V-S-N-E-K-T-Y-R-H-T-Q-K-V-R-K-E-N-H-A-K-M-S-K-L-R-T-I-V-K-K-T-R-S-S-N-E-Q-A-Q-L-N-E-A-Y-K-V-I-D-T-T-A-S-K-G-V-I-H-K-N-K-A-N-R-L-K-S-R-T-A-K-A-F-K-T-N-L-E-V-T-A"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-K-Y-T-I-S-K-H-R-L-E-E-L-Q-L-E-L-R-E-I-L-D-V-K-W-P-A-I-T-K-Q-L-Q-D-A-R-E-Q-G-D-L-S-E-N-A-D-Y-D-A-A-K-N-E-Q-A-A-L-K-K-R-K-D-E-I-E-E-I-L-E-N-Y-E-L-I-E-D-V-L-R-S-T-D-E-V-S-I-G-S-T-I-E-I-Y-N-Y-Q-K-D-C-E-E-V-I-T-L-V-G-S-M-D-S-D-P-F-A-N-K-I-S-I-D-T-P-L-G-K-A-L-V-K-Q-K-K-G-T-E-V-T-V-H-T-L-A-S-P-Y-K-V-K-I-I-K-I-I-D"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-T-I-I-Q-A-K-D-L-R-A-G-H-T-F-L-Y-K-G-N-I-Y-Q-V-I-E-N-S-F-N-K-T-A-M-R-E-G-I-V-K-C-K-V-K-N-L-R-T-G-A-I-T-I-E-V-L-T-G-E-K-L-E-Q-A-V-I-E-K-S-K-M-T-F-S-Y-D-D-G-S-G-Y-V-F-M-D-N-D-T-Y-E-Q-I-S-I-P-Y-S-Q-L-S-W-E-K-N-F-I-E-E-G-T-E-V-S-V-M-R-Y-D-G-E-L-M-G-V-S-L-P-D-Q-L-V-V-T-I-I-E-A-E-E-A-V-Q-G-N-S-V-Q-N-A-T-K-R-A-W-L-E-S-K-W-E-F-Q-V-P-Q-F-I-K-S-G-E-K-V-I-I-N-P-S-N-G-Q-Y-V-G-R-A-K"} +{"text": "### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-I-K-S-I-W-I-A-G-G-C-F-W-G-I-Q-K-Y-F-D-S-I-I-G-V-N-H-T-V-V-G-Y-S-Q-G-N-V-I-N-P-S-Y-E-Q-V-C-T-Q-T-T-N-H-T-E-T-V-Q-I-D-Y-D-D-R-F-V-S-L-I-S-I-L-E-H-L-Y-Q-I-I-D-P-F-S-L-N-K-Q-G-D-D-V-G-S-Q-Y-R-S-G-I-Y-Y-V-D-H-D-D-E-F-I-I-K-D-F-L-L-K-K-Q-N-Q-T-P-K-K-I-M-I-E-V-E-R-L-R-N-F-N-I-A-E-E-Y-H-Q-K-Y-L-D-K-N-P-N-S-Y-C-H-V-D-L-S-L-S-K-K-E-F-R"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-A-K-I-K-A-K-T-R-S-Q-M-I-D-E-L-S-K-M-L-N-I-E-K-K-Q-T-K-A-F-M-D-T-Y-E-A-F-L-I-L-E-L-S-R-A-K-E-V-R-L-G-N-I-G-K-F-K-V-S-V-R-A-E-R-K-G-I-N-P-K-T-G-E-T-V-I-I-P-E-K-T-I-P-K-F-T-F-T-K-G-I-K-E-I-I-N-A-G-I-S-I-D-N-E-R-V-S-I-D-D-N-D-F-D-D-D-D-E-F-V-E-E-Y-I-V-S-E-N-N"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-K-K-K-L-S-F-T-N-G-I-A-Y-I-H-A-T-K-N-N-T-I-I-T-L-A-D-E-Q-G-S-V-L-S-W-A-S-S-G-S-I-G-Y-K-G-T-K-K-K-T-P-Y-S-A-G-I-A-A-E-A-A-A-K-A-V-I-D-M-G-L-K-S-V-E-V-H-V-N-G-T-G-A-S-R-D-T-A-I-R-S-L-Q-A-A-G-L-E-V-T-K-I-K-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-P-R"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-D-T-E-K-L-K-M-L-G-K-I-V-E-V-L-Q-G-G-N-F-R-V-Q-L-E-N-G-I-T-I-M-S-H-V-S-G-K-M-R-V-N-K-I-N-I-L-P-G-D-T-V-D-V-E-L-S-P-Y-D-L-T-R-G-R-I-T-Y-R-H-R-D-N"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-L-H-N-L-E-Y-K-K-G-S-R-N-H-K-E-K-R-V-G-R-G-H-G-S-G-L-G-K-T-S-G-R-G-Q-D-G-Q-K-A-R-K-S-G-M-V-R-L-A-F-E-G-G-Q-T-P-L-Y-R-R-V-P-K-V-G-F-N-N-D-R-F-A-N-K-Y-N-V-V-T-L-I-S-L-V-K-Y-E-T-K-E-L-T-V-E-F-M-Y-A-N-K-I-A-K-N-E-D-L-P-I-K-V-I-G-N-A-V-L-P-S-G-T-V-V-S-A-H-K-F-S-K-G-A-L-E-S-I-S-N-S-K-A-K-A-Q-I-L-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-K-R-I-N-F-S-R-A-K-Q-R-A-L-R-A-K-R-L-H-V-K-I-R-N-L-Q-L-A-A-N-K-P-V-L-V-I-T-K-T-N-A-H-I-W-A-Q-L-I-C-Y-N-K-N-I-T-L-A-S-S-S-S-V-Q-L-D-L-Q-N-G-N-K-D-N-A-R-L-V-G-V-D-I-A-K-K-A-L-A-Q-G-F-K-Q-V-I-F-N-K-N-G-A-K-Y-H-G-R-I-K-A-L-A-D-A-A-R-E-A-G-L-E-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-Y-L-D-P-I-A-E-L-I-T-K-I-N-N-G-R-K-A-H-K-A-E-V-S-F-A-T-S-K-L-K-T-A-I-L-E-L-L-V-K-E-G-Y-I-K-S-Y-D-I-R-P-T-E-N-N-K-S-E-T-V-V-K-L-K-Y-K-N-Q-T-T-S-S-I-N-G-F-K-Q-I-S-K-P-G-L-R-I-Y-S-T-H-L-N-L-P-K-V-L-N-G-L-G-I-A-I-I-T-T-S-K-G-V-M-S-D-K-Q-A-R-K-E-N-V-G-G-E-V-I-A-Y-V-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-F-L-K-D-L-Y-K-N-K-V-A-K-D-L-Q-K-E-F-A-Y-S-S-V-M-Q-I-P-K-I-E-K-V-V-I-N-A-G-I-G-N-A-V-A-D-K-K-H-L-E-A-A-I-S-E-L-T-L-I-T-G-Q-R-P-V-E-T-K-A-K-K-S-I-A-T-F-K-L-R-A-G-Q-S-I-G-A-K-V-T-L-R-G-D-R-M-W-A-F-I-E-T-L-F-N-I-A-L-P-R-V-R-D-F-K-G-I-S-N-N-S-F-D-N-Q-G-N-Y-T-L-G-I-K-E-Q-I-I-F-P-Q-V-V-Y-D-D-V-K-S-V-R-G-F-D-V-T-F-V-T-T-A-K-T-A-Q-E-A-K-A-L-L-V-G-L-G-A-P-F-Q-K-V-R-G-D-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-N-R-I-K-K-G-D-T-V-V-V-I-S-G-K-N-K-N-K-S-G-V-V-I-Q-V-N-P-K-E-Q-T-A-L-V-E-G-V-N-K-I-K-R-H-Q-K-K-D-Q-T-H-E-Q-S-G-I-I-E-K-E-A-P-I-R-L-C-K-L-A-L-V-D-P-K-G-K-D-K-G-K-A-T-K-V-K-Y-L-L-K-D-N-K-K-V-R-V-A-R-K-S-G-S-E-L-D-V-N-K-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-H-M-T-R-L-K-V-A-D-N-T-G-A-K-E-V-G-V-I-K-V-L-G-G-S-K-K-R-Y-A-S-V-G-D-I-V-V-V-S-V-K-K-A-T-P-A-G-L-I-A-K-G-Q-M-A-K-A-V-I-V-R-T-K-K-S-I-R-R-E-S-G-L-L-I-R-F-D-E-N-A-C-V-L-I-K-E-D-K-T-P-R-G-S-R-I-F-G-P-V-A-R-E-I-R-D-R-G-Y-T-K-I-A-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-S-R-R-K-V-L-E-G-L-V-V-S-D-K-M-Q-K-T-V-V-V-S-V-E-T-K-S-K-H-P-I-Y-R-K-L-V-I-S-H-K-K-Y-H-A-H-N-D-N-D-D-A-K-V-G-D-L-V-E-I-T-E-T-R-P-L-S-A-T-K-N-W-R-V-S-K-I-L-E-R-A-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-P-H-K-V-S-Y-E-G-K-A-K-G-N-K-Q-V-D-F-G-E-F-G-L-M-A-L-E-G-A-W-I-D-A-R-Q-I-E-S-A-R-I-A-I-S-K-R-L-L-K-T-G-K-M-W-I-R-I-F-P-H-M-S-L-T-K-K-P-L-E-V-R-M-G-S-G-K-G-S-P-E-K-W-V-A-V-V-K-A-G-T-V-M-F-E-I-A-N-V-S-E-E-L-M-C-E-A-L-R-A-A-G-N-K-L-P-I-K-V-K-I-V-K-K-G-E-A-N"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-L-K-K-G-A-Y-A-D-P-S-L-L-K-K-V-E-A-A-N-A-S-V-S-K-K-P-I-K-T-W-S-R-R-S-Q-I-F-P-N-F-V-G-L-T-F-E-V-H-N-G-K-T-F-L-K-V-Y-V-T-E-D-M-I-G-H-K-L-G-E-F-A-P-T-R-N-F-K-N-H-T-E-A-K-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-E-L-T-R-V-I-L-H-P-Y-T-T-E-K-T-Y-S-I-R-N-K-S-E-H-E-T-L-T-F-I-V-D-K-N-A-N-K-Y-Q-I-R-E-A-F-I-A-I-F-G-L-K-P-L-K-I-R-T-T-N-R-R-P-A-K-I-R-T-S-T-A-R-P-G-Y-T-K-A-K-K-I-A-Y-V-V-M-P-V-G-V-K-V-A-V-S-K-E-E-V-E-A-A-N-A-K"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-N-Q-E-L-R-I-R-L-E-S-Y-D-H-R-L-L-D-D-T-V-K-T-I-V-N-I-S-N-S-T-G-S-K-L-R-G-P-I-P-L-P-T-K-K-E-I-F-T-I-L-R-S-P-H-V-N-K-S-S-R-E-Q-F-E-R-R-T-H-K-R-L-I-I-L-E-N-P-Q-P-K-T-M-E-A-L-K-R-L-S-V-P-F-G-V-E-V-T-F-K-I"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-R-V-K-G-G-S-V-T-R-Q-R-R-K-R-W-L-E-K-A-E-G-S-W-G-T-R-N-T-S-Y-R-I-A-R-Q-T-V-I-R-A-A-E-Y-A-Y-R-D-R-R-N-K-K-R-D-F-R-K-L-W-I-S-R-I-N-A-A-V-R-E-L-G-Y-T-Y-S-Q-F-M-N-A-L-V-K-A-N-V-V-T-K-D-G-Q-G-L-N-R-K-M-L-S-E-L-A-I-N-N-P-E-A-F-N-Q-L-V-D-K-V-M-K"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-S-N-N-D-A-R-K-N-Q-P-L-I-N-D-Q-I-R-F-R-T-M-V-V-I-D-D-H-G-N-N-L-G-E-M-N-R-I-D-A-L-N-L-A-A-S-K-N-L-D-L-V-V-I-A-K-K-G-N-I-P-V-T-K-I-L-D-Y-G-K-Y-K-Y-E-Q-K-R-R-Q-K-E-S-R-K-N-Q-T-I-I-K-V-K-E-I-K-I-K-P-M-I-G-E-H-D-L-K-V-R-A-E-N-A-K-R-W-L-E-D-K-D-N-V-K-F-V-I-E-A-R-G-R-M-C-T-K-D-E-F-I-V-Q-A-Y-E-K-F-I-D-L-I-K-D-Y-G-T-V-V-Q-A-N-K-K-V-S-N-Y-R-Y-E-T-I-I-E-P-I-K-K"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-K-R-G-K-L-I-V-F-S-G-P-S-G-V-G-K-H-T-I-L-S-K-I-I-N-R-K-D-L-N-L-A-Y-S-I-S-M-T-T-R-K-K-R-E-G-E-V-N-G-V-D-Y-Y-F-V-N-D-E-E-F-K-K-A-I-L-N-N-E-L-I-E-W-A-E-F-V-G-N-K-Y-G-T-P-R-T-I-V-E-K-L-R-D-E-G-K-N-V-I-L-E-I-E-V-V-G-A-L-K-V-L-D-L-Y-K-N-D-D-L-I-S-I-F-L-L-P-P-S-I-D-E-L-K-K-R-L-L-K-R-N-T-E-T-L-E-T-I-K-K-R-I-Q-K-A-T-H-E-I-T-I-K-D-Y-Y-Q-Y-N-I-I-N-D-N-P-D-H-A-A-N-Q-L-A-E-I-I-L-N-E-I-K-Q-S"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-I-F-Q-T-G-G-K-Q-Y-K-V-Q-Q-G-E-K-I-Y-V-E-K-L-D-L-E-V-G-S-K-I-S-F-D-Q-V-I-M-V-E-G-S-V-G-T-P-F-V-K-N-A-V-V-N-A-T-V-I-K-Q-G-K-Q-K-K-I-N-I-I-K-F-K-S-K-K-H-H-L-K-R-Q-G-H-R-Q-P-Y-T-Q-L-V-I-D-S-I-S-V-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-V-S-K-Q-Q-K-H-D-L-T-V-K-F-G-G-S-A-S-N-T-G-K-T-E-V-Q-V-A-I-L-S-A-E-I-D-S-L-T-T-H-M-I-E-N-K-K-D-K-A-S-K-R-G-L-Y-K-K-V-A-Q-R-K-K-L-L-S-Y-L-Q-R-V-D-I-E-R-Y-R-A-L-I-K-E-L-N-L-R-G"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-M-I-K-I-I-S-V-G-K-L-K-Q-K-A-F-V-D-L-I-N-D-Y-L-K-R-I-N-H-Y-L-K-C-Q-E-I-V-V-S-D-E-P-E-P-V-Q-I-S-N-K-S-L-E-Q-I-K-S-K-E-A-S-K-I-F-K-N-I-N-Q-N-D-F-V-I-A-L-I-I-E-S-N-I-I-S-S-E-T-L-A-K-K-I-Q-Q-W-L-N-T-F-S-H-D-I-C-F-I-I-G-G-S-N-G-L-H-E-S-I-Y-E-R-A-N-Y-H-L-S-M-S-K-M-T-F-A-H-G-L-A-K-V-M-L-C-E-Q-I-Y-R-A-L-S-I-L-N-N-G-K-Y-H-K"} +{"text": "### FUNCTION The phosphoenolpyruvate-dependent sugar phosphotransferase system , a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane ### SEQUENCE -M-Q-N-L-N-N-K-Q-K-T-L-I-I-F-L-G-I-I-T-F-G-I-F-I-I-Y-F-F-T-K-A-K-K-V-S-Q-I-R-N-T-H-L-I-V-S-S-N-I-P-F-S-L-N-D-F-Y-N-C-I-G-S-K-N-N-L-V-N-V-D-A-T-I-N-T-L-K-I-E-L-K-E-I-N-A-L-N-N-E-K-L-K-V-L-G-A-K-G-I-M-C-N-Q-T-K-I-S-I-I-F-G-D-F-C-L-E-L-K-E-L-I-K-K-D-L-F-S"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-S-S-L-K-P-V-E-K-Y-A-Y-S-I-F-E-I-A-K-E-E-K-K-L-D-L-Y-K-H-N-L-E-T-I-N-S-I-I-E-E-V-P-A-F-F-E-A-V-G-D-P-A-R-D-R-N-E-R-K-Q-I-V-I-K-N-L-E-G-E-I-D-I-Y-L-I-S-L-I-D-L-L-I-D-V-K-S-V-K-L-L-K-K-I-V-L-K-A-L-D-F-V-N-E-A-L-S-V-K-K-V-L-I-T-T-A-Y-E-L-T-K-N-Q-I-D-R-L-L-Q-S-L-K-K-K-Y-V-C-E-K-I-E-P-I-V-V-V-D-K-S-I-I-G-G-L-S-I-N-F-E-S-Q-V-L-D-N-S-L-K-T-K-L-F-N-I-V-K-K-V-N"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-N-L-T-K-L-K-I-V-T-P-Y-A-Q-I-L-E-K-D-V-Y-S-V-E-L-K-T-S-E-G-R-I-T-V-L-P-D-H-N-P-L-M-S-T-I-E-N-H-V-A-Y-I-R-E-L-P-N-T-P-R-K-P-L-L-L-L-D-G-I-V-Y-I-E-Q-H-Q-V-R-V-F-S-D-Y-F-K-F-L-D-E-I-Q-I-D-E-I-N-S-S-L-N-Q-L-K-H-D-L-N-N-E-E-D-D-K-K-K-L-Q-L-K-S-K-I-K-L-N-E-S-I-L-I-A-Y-K-D-R"} +{"text": "### FUNCTION Key enzyme in folate metabolism Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis ### SEQUENCE -M-L-K-L-I-W-C-Q-T-L-N-G-G-I-S-K-N-N-K-L-P-W-Y-I-K-E-E-L-D-H-F-Y-K-T-T-K-N-H-K-I-I-M-G-K-N-T-F-D-S-L-D-Q-K-P-L-N-N-R-T-N-I-I-F-S-S-I-M-Q-T-P-E-D-E-S-Y-F-V-T-N-D-F-Q-Q-V-L-N-D-A-K-K-E-D-I-F-I-I-G-G-K-E-L-F-D-I-F-L-A-Y-A-D-V-L-I-V-S-V-L-K-D-Y-Y-D-C-D-L-Y-M-K-V-D-Y-N-N-F-N-L-D-K-Q-D-V-Y-D-N-F-I-V-N-Y-Y-S-N-K-K-E-K"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-D-F-Q-K-L-A-Q-E-L-K-K-M-Q-N-T-L-S-K-K-Q-K-E-F-E-E-K-V-F-D-F-D-Y-K-G-Y-V-L-V-K-I-K-G-D-L-N-I-E-A-I-E-I-K-T-E-I-V-D-P-E-D-K-E-T-L-Q-D-I-L-R-A-A-I-N-E-A-I-S-I-T-C-K-E-R-D-A-I-M-N-A-T-I-P-K-G-T-G-L-F"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-E-K-Y-L-I-V-G-L-G-N-P-G-S-N-Y-A-K-T-R-H-N-V-G-F-M-V-I-N-E-I-C-N-K-L-N-L-S-L-D-S-S-K-F-N-G-I-F-T-K-T-I-Y-N-N-S-I-V-F-F-C-Q-P-T-T-Y-M-N-L-S-G-E-F-V-I-K-M-L-N-F-Y-N-I-P-I-K-N-L-I-V-I-Y-D-D-V-D-T-K-L-G-T-I-K-L-R-K-K-G-S-S-G-G-Q-N-G-I-K-N-I-I-N-I-L-K-T-D-E-I-K-R-I-R-I-G-I-D-K-D-P-H-I-K-L-D-Q-Y-V-L-S-N-F-K-I-D-E-L-V-I-I-K-P-A-I-I-K-G-A-L-A-T-L-A-A-I-G-E-D-F-D-K-V-M-N-K-F-N"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-I-V-S-N-K-H-A-R-R-N-Y-E-L-L-D-F-F-E-C-G-I-V-L-K-G-T-E-V-K-S-I-S-R-A-N-C-S-I-N-E-A-Y-V-Q-I-I-K-N-Q-A-L-I-L-N-M-H-V-A-N-F-F-E-G-N-N-F-N-Q-D-P-Y-R-N-R-K-L-L-L-H-K-K-E-I-I-R-L-Q-H-L-V-K-T-Q-H-M-T-I-V-P-T-K-I-Y-W-K-N-N-K-L-K-I-E-I-A-L-G-K-G-K-Q-L-H-D-K-R-E-D-I-K-K-R-D-L-A-R-E-T-R-L-F"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-A-L-T-I-V-L-I-L-F-S-V-L-A-L-I-I-G-L-L-L-S-R-T-S-P-S-G-G-L-S-S-L-N-G-Q-D-L-E-I-F-K-K-T-K-D-R-G-W-I-K-G-L-Q-V-F-M-F-L-L-T-I-V-M-I-L-I-I-I-F-Y-R-V-S"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-K-L-T-I-E-Q-F-I-A-A-I-K-E-M-S-M-L-E-L-N-D-L-V-K-A-I-E-T-E-F-G-V-S-A-A-A-P-V-A-A-A-A-A-P-V-A-A-E-A-P-T-E-V-T-I-K-L-V-E-A-G-T-N-K-V-G-V-I-K-L-I-R-E-I-T-G-L-G-L-M-E-A-K-T-A-A-E-T-A-G-S-V-I-K-E-D-V-K-T-E-E-A-N-E-I-K-K-K-F-D-E-L-G-A-K-V-Q-L-V"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-N-V-R-P-S-V-V-F-K-Q-Q-E-V-N-H-M-A-D-I-L-K-N-S-K-S-F-I-V-F-E-Y-H-G-L-T-A-A-N-I-L-A-L-R-N-V-L-H-S-S-N-S-K-L-Y-V-L-K-N-N-I-T-A-R-A-F-E-K-A-G-V-S-G-F-E-N-Q-L-T-G-P-N-A-V-A-V-A-M-D-D-E-I-A-A-I-K-A-V-N-D-V-A-K-E-F-D-F-V-K-I-K-G-A-Y-L-E-N-K-F-A-D-T-H-K-I-D-Q-L-A-A-I-P-G-R-E-G-L-Y-S-M-L-L-S-C-F-T-A-P-L-R-N-V-M-Y-G-L-K-A-V-A-E-Q-K-G-E"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-R-D-I-H-P-V-S-K-P-C-V-Y-N-C-V-T-C-K-K-E-F-I-I-D-S-A-A-K-N-T-E-V-A-I-E-V-C-S-N-C-H-T-F-F-I-G-K-Q-N-A-T-T-T-L-R-G-R-A-E-K-L-N-N-R-F-E-A-G-L-N-N-I-N-K-K-P-E-K-K-K-I-Q-G-K-S-E-P-R-K-S-L-N-E-L"} +{"text": "### FUNCTION Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters ### SEQUENCE -S-E-A-A-F-Q-K-A-A-E-E-V-K-E-L-K-S-Q-P-T-D-Q-E-M-L-D-V-Y-S-H-Y-K-Q-A-T-V-G-D-V-N-T-D-R-P-G-M-L-D-F-K-G-K-A-K-W-D-A-W-N-A-L-K-G-M-S-K-E-D-A-M-K-A-Y-V-A-K-V-E-E-L-K-G-K-Y-G-I"} +{"text": "### FUNCTION Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle ### SEQUENCE -F-V-P-F-F-T-Q-S-D-I-Q-K-M-Q-E-K-E-R-N-K-G-Q"} +{"text": "### FUNCTION Binds and may inhibit nicotinic acetylcholine receptors ### SEQUENCE -S-K-C-R-I-G-K-D-G-F-Y-S-V-T-C-T-E-K-E-N-L-C-F-T-Q-F"} +{"text": "### FUNCTION Binds and may inhibit nicotinic acetylcholine receptors ### SEQUENCE -K-K-C-L-T-K-Y-S-A-G-L-Q-T-S-Q-T-C-P-A-G-Q-K-I-C-F-K-K-W"} +{"text": "### FUNCTION Binds and may inhibit nicotinic acetylcholine receptors ### SEQUENCE -L-K-C-Y-S-S-R-T-E-T-M-T-C-P-E-G-K-D-K-C-E-K-Y-A-V"} +{"text": "### FUNCTION Glucagon plays a key role in glucose metabolism and homeostasis Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis ### SEQUENCE -H-S-Q-G-S-F-T-S-D-Y-S-K-Y-L-D-S-K-Q-A-K-D-F-V-I-W-L-M-N-T"} +{"text": "### FUNCTION Somatostatin inhibits the release of somatotropin ### SEQUENCE -A-A-A-A-P-G-A-A-G-G-A-Q-L-P-L-G-N-R-E-R-K-A-G-C-K-N-F-F-W-K-T-F-S-S-C"} +{"text": "### FUNCTION Snake venom phospholipase A2 homolog that lacks enzymatic activity ### SEQUENCE -S-L-V-E-L-G-K-M-I-L-Q-E-T-G-K-N-P-V-T-Y-G-A-Y"} +{"text": "### FUNCTION Smooth muscle contraction Probably plays a role for this system in cardiovascular regulation in fish May target bradykinin receptors ### SEQUENCE -K-R-P-P-G-W-S-P-L-R"} +{"text": "### FUNCTION Somatostatin inhibits the release of somatotropin ### SEQUENCE -S-A-N-P-A-L-A-P-R-E-R-K-A-G-C-K-N-F-F-W-K-T-F-T-S-C"} +{"text": "### FUNCTION Anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factors IX in the presence of calcium with a 1 to 1 stoichiometry ### SEQUENCE -D-C-P-S-D-W-S-P-Y-E-G-H-C-Y-K-H-F-I-K-W-M-N-N-E-D-A-E-R-F-C"} +{"text": "### FUNCTION Inhibits acetylcholinesterase ### SEQUENCE -T-M-C-Y-S-H-T-T-T-S-R-A-I-L-T-N-C-G-E-N-S-C-Y-R-K-S-R-V-H-P"} +{"text": "### FUNCTION Blocks voltage-gated potassium channels This is the slowly inactivating phase of potassium efflux which is blocked by this toxin ### SEQUENCE -M-I-C-Y-S-H-K-T-P-Q-P-S-A-T-I-G-C-E-E-K-T-C-Y-K-K-S-V-R-K-L"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -P-R-R-R-R-Q-A-S-R-P-V-R-R-R-R-R-T-R-R-S-T-A-E-R-R-R-R-R-V-V-R-R-R-R"} +{"text": "### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 with moderate affinity ### SEQUENCE -L-K-C-K-K-L-V-P-L-F-S-K-T-C-P-A-G-K-N-L-C-Y-K-M-F-M-V-A-A-P-H-V-P-V-K-R-G-C-I-D-V-C-P-K-S-S-L-L-V-K-Y-V-C-C-N-T-D-R-C-N"} +{"text": "### FUNCTION May function as a transcription factor ### SEQUENCE -E-D-I-W-K-K-F-E-L-L-P-T-P-P-L-S-P-S-R-A-A-L-P-G-D-P-G-E-L-G-A-V-A-G-D-C-S-L-M-G-F-G-L-T-D-P-L-D-W-A-S-E-L-L-L-L-P-G-D-D-I-W-G-A-S-D-G-D-L-F-G-S-V-L-D-T-T-D-N-S-I-I-I-Q-D-C-M-W-S-G-F-S-A"} +{"text": "### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-T-V-C-L-D-L-G-Y-T-L-K-C-N-K-L-V-P-L-F-Y-K-T-C-P-A-G-K-N-L-C-Y-K-M-Y-M-V-A-T-P-K-V-P-V-K-R-G-C-I-D-V-C-P-K-S-S-L-L-V-K-Y-V-C-C-N-T-D-R-C-N"} +{"text": "### FUNCTION Gastrointestinal hormone and neuropeptide ### SEQUENCE -M-I-H-S-G-A-V-M-S-M-S-I-L-A-F-C-L-L-A-C-I-H-S-G-I-N-A-Y-P-A-K-P-A-S-P-R-D-G-A-P-P-E-E-L-A-K-Y-Y-S-A-L-R-H-Y-I-N-L-I-T-R-Q-R-Y-G-K-R-D-T-P-D-T-V-F-S-D-V-L-M-R-E-S-T-E-S-I-P-G-S-N-Y-V-R-Y-D-G-L-P-L-W"} +{"text": "### FUNCTION Beta-1-bungarotoxin is a presynaptic neurotoxin of the venom The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and blocks voltage-gated potassium channels ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-C-A-E-L-T-P-V-S-S-K-D-R-H"} +{"text": "### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-D-C-S-K-S-G-T-C-N-C-G-G-S-C-T-C-T-N-C-S-C-T-T-C-K-K-S-C-C-P-C-C-P-S-G-C-T-K-C-A-S-G-C-V-C-K-G-K-T-C-D-T-S-C-C-Q"} +{"text": "### FUNCTION Urotensin is found in the teleost caudal neurosecretory system It has a suggested role in osmoregulation and as a corticotropin-releasing factor The non-hormonal portion of this precursor may be a urotensin binding protein, urophysin ### SEQUENCE -M-K-P-V-P-L-V-L-L-I-T-S-V-L-L-T-T-H-I-P-L-S-T-C-R-P-R-D-L-S-L-V-N-S-Q-L-D-D-V-L-S-N-G-A-G-D-D-A-M-S-Y-L-V-G-E-K-L-L-Q-Y-L-Q-R-N-L-G-A-Q-K-A-S-G-V-L-H-L-P-H-F-P-A-A-Q-L-R-S-P-H-E-D-S-S-L-E-E-L-T-E-F-S-K-R-N-D-D-P-P-I-S-I-D-L-T-F-H-L-L-R-N-M-I-E-M-A-R-N-E-N-Q-R-E-Q-A-G-L-N-R-K-Y-L-D-E-V-G-K"} +{"text": "### FUNCTION Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level ### SEQUENCE -M-S-N-A-S-G-T-L-L-S-Y-M-F-M-M-L-L-G-L-T-L-A-S-L-V-P-H-E-T-D-D-G-D-L-N-A-E-I-S-L-A-N-R-H-S-Q-G-S-F-T-S-D-Y-S-K-H-L-D-V-K-Q-A-K-D-F-V-T-W-L-L-N-T-K-R-R-G-V-D-A-Q-A-G-A-N-L-E-K-R-H-S-D-G-S-F-T-N-D-M-N-V-M-L-D-R-M-S-A-K-N-F-L-E-W-L-K-Q-Q-G-R-G"} +{"text": "### FUNCTION Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level ### SEQUENCE -M-S-D-P-G-F-L-A-A-P-V-L-L-L-L-L-V-S-L-A-S-A-S-L-E-Q-A-A-S-R-D-D-D-S-A-E-R-P-L-S-K-R-H-S-E-G-T-F-T-S-D-Y-S-K-Y-L-E-N-K-Q-A-K-D-F-V-R-W-L-M-N-A-K-R-G-G-S-E-L-Q-R-R-H-A-D-G-T-F-T-N-D-M-T-S-Y-L-D-A-K-A-A-R-D-F-V-S-W-L-A-R-S-D-K-S-R-R-D-G-G-D-H-L-A-E-N-S-E-D-K-R-H-A-E-D-V-N-A-L-L-D-R-T-M-A-K-T-F-I-E-W-L-E-K-Q-N-S-N-D-Q-T-D"} +{"text": "### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-D-S-N-T-I-T-S-F-Q-D-I-L-Q-R-M-S-K-M-Q-L-E-S-S-S-V-D-L-N-G-M-I-T-Q-F-E-R-L-K-I-Y-R-D-S-L-G-E-S-M-M-R-M-G-D-L-H-S-L-Q-N-R-N-A-T-W-R-N-E-L-S-Q-K-F-E-E-I-R-W-L-I-A-E-C-R-N-I-L-T-K-T-E-N-S-F-E-Q-I-T-F-L-Q-A-L-Q-L-L-L-E-V-E-S-E-I-R-T-F-S-F-Q-L-I"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-P-I-T-S-P-S-Q-F-V-F-L-S-S-V-W-A-D-P-I-E-L-L-N-V-C-T-N-S-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-S-E-V-W-E-P-F-P-Q-S-T-V-R-F-P-G-D-V-Y-K-V-Y-R-Y-N-A-V-L-D-P-L-I-T-A-L-L-G-T-F-D-T-R-N-R-I-I-E-V-E-N-R-Q-S-P-T-T-A-E-T-L-D-A-T-R-R-V-D-D-A-T-V-A-I-R-S-A-I-N-N-L-V-N-E-L-V-R-G-T-G-L-Y-N-Q-N-T-F-E-S-M-S-G-L-V-W-T-S-A-P-A-S"} +{"text": "### FUNCTION Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates Responsible for the transcription of early, intermediate and late genes DNA-dependent RNA polymerase associates with the early transcription factor ### SEQUENCE -M-V-F-Q-L-V-C-S-T-C-G-R-D-I-S-E-E-R-Y-A-L-L-I-K-K-I-D-L-K-T-V-L-R-G-V-K-N-N-C-C-R-L-K-L-S-T-Q-I-E-P-Q-R-N-L-T-V-E-P-L-L-D-I-N"} +{"text": "### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-N-P-V-T-V-F-F-V-V-V-V-T-V-A-A-C-M-I-L-F-Q-V-Y-S-I-Y-L-N-Y-D-N-I-K-E-F-N-A-M-H-S-P-L-E-Y-S-K-M-V-N-V-T-A-I-D-R-R-I-Q-D-A-N-D-D-I-Y-D-A-K-Q-K-W-R-C-V-K-L-D-D-S-Y-V-S-L-S-M-F-G-Y-K-S-D-G-I-G-I-R-R-F-R-T-L-N-S-C-I-D-Y-T-F-S-T-S-T-H-S-S-I-L-N-P-C-I-S-P-N-D-P-K-S-R-E-C-T-F-L-K-S-V-L"} +{"text": "### FUNCTION Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates Responsible for the transcription of early, intermediate and late genes DNA-dependent RNA polymerase associates with the early transcription factor ### SEQUENCE -M-V-F-Q-L-I-C-S-T-C-G-R-D-I-S-E-E-R-F-A-L-L-I-K-K-I-A-L-K-T-V-L-K-G-V-K-N-S-C-C-R-L-K-L-S-T-Q-I-E-P-Q-R-N-L-T-V-E-P-L-L-D-I-N"} +{"text": "### FUNCTION Pathogenicity determinant , a mechanism of plant viral defense that limits the accumulation of viral RNAs ### SEQUENCE -M-G-L-L-T-C-M-F-S-S-N-S-K-E-S-S-S-V-R-I-K-D-S-S-I-S-H-P-H-T-G-Q-H-I-S-I-R-T-F-R-E-L-K-A-Q-Q-M-S-N-P-T-W-K-K-T-E-T-C-L-I-M-E-F-S-R-S-M-E-D-R-L-E-E-V-A-N-L-P-T-T-H-M-P-R-Q-S-I-Q-G-P-K-L-R-P-S-I-Y"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-N-I-T-S-S-N-Q-Y-Q-Y-F-A-A-M-W-A-E-P-T-A-M-L-N-Q-C-V-S-A-L-S-Q-S-Y-Q-T-Q-A-A-R-D-T-V-R-Q-Q-F-S-N-L-L-S-A-I-V-T-P-N-Q-R-F-P-E-T-G-Y-R-M-Y-I-N-S-A-V-L-K-P-L-Y-E-S-L-M-K-S-F-D-T-R-N-R-I-I-E-T-E-E-E-S-R-P-S-A-S-E-V-A-N-A-T-Q-R-V-D-D-A-T-V-A-I-R-S-Q-I-Q-L-L-L-N-E-L-S-N-G-H-G-L-M-N-R-A-E-F-E-V-L-L-P-W-A-T-A-P-A-T"} +{"text": "### FUNCTION May be a minor structural protein present in one or two copies per virion May play a role in RNA genome packaging ### SEQUENCE -M-S-W-I-A-G-A-M-Q-G-A-G-L-L-G-D-L-A-G-T-I-G-Q-I-V-L-H-N-K-Q-L-N-I-M-N-S-F-N-Q-A-Q-I-Q-L-A-K-D-Q-L-K-Q-N-Q-Q-L-A-N-Q-Y-Y-E-F-N-A-N-L-P-V-N-Q-Y-N-S-A-V-S-A-G-F-D-S-V-S-A-R-Q-L-A-G-S-R-E-V-R-Y-L-G-G-Q-Q-T-P-L-V-H-Q-G-Q-I-H-Q-M-M-F-S-P-K-H-L-M-Q-A-Q-H-V-V-G-T-F-S-R-G-M-P-G-V-T-P-S-K-G-L-P-R-P-Q-G-V-T-A-K-V-P-V-A-G-A-T-T-T-H-S-K-V"} +{"text": "### FUNCTION Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm Once the complex reaches the host nucleus, it interacts with the capsid portal vertex This portal forms a ring in which genomic DNA is translocated into the capsid ### SEQUENCE -M-M-D-S-S-P-E-K-T-N-L-E-L-L-Y-E-Q-V-C-E-Q-G-R-E-F-E-V-V-F-Y-P-M-L-P-R-L-Y-E-M-M-L-P-S-L-E-A-R-L-N-F-L-S-V-G-Y-R-H-V-A-F-S-R-Y-V-H-G-D-V-D-C-V-H-R-E-V-M-A-Q-K-M-V-L-L-T-S-I-L-S-K-L-L-N-V-N-G-I-L-E-H-Q-E-Y-L-N-T-E"} +{"text": "### FUNCTION Down-regulates the TCR/CD3E complex and the transferrin receptor TFRC in host T-cells by blocking them from recycling back to the cell surface ### SEQUENCE -M-D-R-P-R-T-P-P-P-S-Y-S-E-V-L-M-M-D-V-M-Y-G-Q-V-S-P-H-A-S-N-D-T-S-F-V-E-C-L-P-P-P-Q-S-S-R-S-A-W-N-L-W-N-K-R-R-K-T-F-A-F-L-V-L-T-G-L-A-I-A-M-I-L-F-I-A-F-V-I-Y-V-F-N-V-N-R-R-K-K"} +{"text": "### FUNCTION Plays an essential role for the viral pathogenicity ### SEQUENCE -M-P-G-N-N-H-N-D-R-P-V-A-L-I-M-S-R-L-S-R-D-P-R-D-C-I-H-H-T-V-D-T-R-G-M-T-P-G-K-I-I-H-Q-V-I-P-P-H-P-T-Q-M-R-H-T-N-R-P-S-P-P-V-I-L-N-L-Q-I-L-S-E-G-G-H-V-C-A-R-D-V-D-T-A-D-P-V-P-R-A-G-P-E-R-T-I-Q-W-G-T-D-R-D-A-T-E-E-L-A-S-P-A-P-E-E-I-Y-E-D-N-D-S-W"} +{"text": "### FUNCTION Plays a major role in assembly and budding of virion Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form Inhibits viral transcription and stimulates replication ### SEQUENCE -M-P-F-I-R-R-P-K-R-A-I-L-I-P-P-L-H-L-T-L-K-D-D-D-K-V-L-V-V-E-T-V-G-T-L-I-I-S-G-M-T-P-S-N-L-T-E-K-L-G-L-A-M-K-L-A-S-A-I-L-G-G-D-S-H-P-A-F-N-P-L-V-E-I-F-S-G-A-M-E-F-G-A-S-V-E-K-L-D-F-M-T-R-E-N-K-V-I-T-T-Y-K-V-A-R-G-K-A-V-A-L-S-N-F-P-M-E-K-R-V-G-E-K-S-Y-T-T-Q-I-R-N-G-S-I-T-Y-T-G-S-F-L-F-S-A-E-H-V-G-L-K-D-N-R-S-L-F-A-A-G-E-G-L-R-E-S-P-D-M-A-Q-A-R-E-A-F-A-G-S-L-P-K-G-K-N-E-S-S-R-K"} +{"text": "### FUNCTION Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL ### SEQUENCE -M-N-S-R-L-C-I-M-A-L-L-L-C-F-S-Q-A-L-L-G-H-F-T-V-I-E-E-I-E-K-L-K-K-Y-F-N-S-S-S-S-D-V-G-D-Q-K-D-I-V-S-D-I-L-R-N-W-Q-N-D-R-D-V-K-V-I-E-S-Q-I-V-S-F-Y-L-K-L-F-E-A-L-K-E-H-K-T-I-Q-E-S-I-N-T-I-R-A-D-L-I-V-N-F-F-N-N-S-R-E-K-M-D-D-F-I-K-L-T-T-I-P-V-N-D-L-Q-V-Q-R-K-A-V-N-E-L-V-G-V-M-H-R-L-S-S-N-I-R-R-K-K-K-G-S-R-C-C-F-G-G-G-D-R-L-N-Q-N-Y-P-A-R-S-I"} +{"text": "### FUNCTION Probably involved in cell proliferation and cell-cell interactions ### SEQUENCE -M-S-L-L-L-L-V-V-S-A-L-H-I-L-I-L-V-L-L-F-V-A-T-L-D-K-S-W-W-T-L-P-E-K-E-S-L-N-L-W-Y-D-C-T-W-N-T-T-A-K-T-W-A-C-S-N-V-S-E-N-G-W-L-K-A-V-Q-A-L-M-V-L-S-L-I-L-C-C-L-S-F-I-L-F-M-I-Q-L-Y-T-M-R-R-G-G-L-F-Y-A-T-G-L-C-Q-L-C-T-S-A-A-V-F-S-G-A-L-I-Y-A-I-H-A-K-E-I-L-A-K-H-P-S-G-G-S-F-G-Y-C-F-A-L-A-W-V-A-F-P-L-A-L-V-S-G-I-I-Y-I-H-L-R-K-R-E"} +{"text": "### FUNCTION Inhibitor of actin polymerization ### SEQUENCE -M-A-K-I-I-L-R-H-L-I-E-T-P-V-R-Y-Q-E-E-F-E-A-R-G-L-E-D-C-R-L-D-H-T-L-Y-A-L-P-G-P-T-I-E-D-L-S-K-A-R-G-A-G-T-P-Q-A-L-A-E-D-S-A-S-T-E-K-P-P-G-E-G-K-S-R-F-Q-I-L-L-D-V-V-Q-F-L-P-E-D-I-I-I-Q-T-F-E-G-W-L-L-I-K-A-Q-H-G-T-R-M-D-E-H-G-F-I-S-R-S-F-T-R-Q-Y-K-L-P-D-G-V-E-T-K-D-L-S-A-I-L-C-H-D-G-I-L-V-V-E-V-K-D-S-L-G-T-K"} +{"text": "### FUNCTION Inhibitor of actin polymerization ### SEQUENCE -M-A-K-I-I-L-R-H-L-I-E-T-P-V-R-Y-Q-E-E-F-E-A-R-G-L-E-D-C-R-L-D-H-A-L-Y-A-L-P-G-P-T-I-E-D-L-R-K-A-R-G-T-P-K-A-L-A-E-D-S-D-S-A-E-T-P-P-G-E-G-K-S-R-F-Q-I-L-L-D-V-V-Q-F-L-P-E-D-I-I-I-Q-T-F-E-G-W-L-L-I-K-A-Q-H-G-T-R-M-D-E-H-G-F-I-S-R-S-F-T-R-Q-Y-K-L-P-D-G-V-E-T-K-D-L-S-A-I-L-C-H-D-G-I-L-V-V-E-V-K-D-P-L-E-T-K"} +{"text": "### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-Y-T-C-N-S-G-N-Y-S-S-Q-S-F-G-G-F-L-R-Q-P-V-S-T-Y-N-S-F-Y-P-T-S-N-V-V-Y-S-P-K-N-F-Q-L-G-S-S-F-Y-N-G-Q-Q-E-T-F-S-E-P-L-E-G-H-L-P-C-V-G-S-A-S-F-H-T-S-C-F-R-P-K-Q-Y-F-S-S-P-C-Q-G-G-F-T-G-S-F-G-Y-G-N-T-G-F-G-A-F-G-F-G-S-S-G-I-R-S-Q-G-C-G-S-N-F-Y-R-P-G-Y-F-S-S-K-S-I-Q-S-S-Y-Y-Q-P-G-Y-S-S-G-F-C-G-S-N-F"} +{"text": "### FUNCTION May play a role in cell differentiation in the intestinal epithelium ### SEQUENCE -M-A-D-S-E-R-L-S-A-P-G-C-W-L-A-C-T-S-F-S-R-T-K-K-G-I-L-L-F-A-E-I-I-L-C-L-V-I-L-I-C-F-S-A-S-T-T-S-A-Y-S-S-L-S-V-I-E-M-I-C-A-A-V-L-L-V-F-Y-T-C-D-L-H-S-K-I-S-F-I-N-W-P-W-T-D-F-F-R-S-L-I-A-T-I-L-Y-L-I-T-S-I-V-V-L-V-E-G-R-G-S-S-R-V-V-A-G-I-L-G-L-L-A-T-L-L-F-G-Y-D-A-Y-I-T-F-P-L-K-Q-Q-R-H-T-A-A-P-T-D-P-T-D-G-P"} +{"text": "### FUNCTION Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues ### SEQUENCE -E-S-N-Q-G-Y-V-N-S-N-V-G-I-E-L-A-R-Y-E-T-T-N-Y-T-E-S-G-S-F-D-T-D-L-A-R-F-R-G-T-S-D-S-I-H-T-S-R-N-T-Y-T-A-A-D-C-A-T-G-Y-Y-S-F-A-H-E-I-G-H-L-Q-S-A-R-D-I-A-T-D-S-S-T-S-P-Y-A-Y-G-H-G-Y-R-Y-E-P-A-T-G-W-R-T-I-M-A-Y-N-C-T-R-S-C-P-R-L-N-Y-W-S-N-P-N-I-S-Y-D-I-G-P-D-N-Q-R-V-L-V-N-T-K-A-T-I-A-A-F-R"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -A-N-N-P-G-A-R-K-A-I-R-K-I-E-A-R-T-E-V-N"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -A-A-K-I-K-K-G-D-N-V-V-V-L-T-G"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -A-N-N-A-G-A-R-K-A-I-R-K-I-E-A-R-T-E-V-N"} +{"text": "### FUNCTION Antibacterial activity against Xcampestris, especially strain G, and Psolacearum PO1 ### SEQUENCE -A-S-G-G-T-V-G-X-Y-G-A-W-M-R-S-X-S-L-V-S-X-S-T-I-T-T-F-S"} +{"text": "### FUNCTION Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition GvpA forms the protein shell ### SEQUENCE -A-V-E-K-T-N-S-S-S-S-L-G-E-V-V-D-R-I-L-D-K-G-V-V-V-D-L-W-V-R-V-S-L-V-G-I-E-L-L-A-L-E-A-R-V-V-I"} +{"text": "### FUNCTION Together with its co-chaperonin GroES, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding ### SEQUENCE -H-A-K-D-V-V-F-G-G-E-A-R-A-R-M-V-E-G-V-N-I-L-A-N-A"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-D-I-H-P-N-Y-V-E-I-D-A-T-X-S-X-G-N"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-T-N-L-S-I-K-G-V-V-K-E-I-I-K-G-D-K-F-K-V-L-L-E-N-N-L-L-I-E-A-H-V-S-G-K-I-R-M-H-K-I-R-I-L-P-G-D-S-V-E-V-E-F-S-P-Y-D-L-T-K-G-R-I-I-Y-R-H"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-K-H-I-T-N-K-A-E-L-D-Q-L-L-S-T-N-K-K-V-V-V-D-F-Y-A-N-W-C-G-P-C-K-I-L-G-P-I-F-E-E-V-A-Q-D-K-K-D-W-T-F-V-K-V-D-V-D-Q-A-N-E-I-S-S-E-Y-E-I-R-S-I-P-T-V-I-F-F-Q-D-G-K-M-A-D-K-R-I-G-F-I-P-K-N-E-L-K-E-L-L-K"} +{"text": "### FUNCTION Involved in protection of chromosomal DNA from damage under nutrient-limited and oxidative stress conditions Binds heme ### SEQUENCE -M-T-N-T-G-L-V-Q-S-F-S-Q-I-E-P-N-V-L-G-L-E-T-S-V-T-S-Q-I-C-E-G-L-N-R-A-L-A-S-F-Q-V-L-Y-L-Q-Y-Q-K-H-H-F-T-V-Q-G-A-E-F-Y-S-L-H-E-F-F-E-D-S-Y-G-S-V-K-D-H-V-H-D-L-G-E-R-L-N-G-L-G-G-V-P-V-A-H-P-L-K-L-A-E-L-T-C-F-A-I-E-E-D-G-V-F-N-C-R-T-M-L-E-H-D-L-A-A-E-Q-A-I-L-S-L-L-R-R-L-T-A-Q-V-E-S-L-G-D-R-A-T-R-Y-L-L-E-G-I-L-L-K-T-E-E-R-A-Y-H-I-A-H-F-L-A-P-D-S-L-K-L-A"} +{"text": "### FUNCTION Part of the high-affinity ATP-driven potassium transport system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-S-L-I-R-E-L-L-R-A-I-R-I-T-L-I-F-W-L-I-T-A-I-I-Y-P-L-A-I-L-V-V-G-Q-G-L-F-P-Y-Q-A-N-G-S-I-M-Q-N-I-E-A-Q-P-I-G-S-A-L-I-G-Q-V-F-A-S-E-Q-Y-F-H-S-R-P-S-A-S-R-Y-S-Q-G-R-R-A-R-P-T-G-I-S-G-G-S-N-L-A-P-S-N-P-A-L-L-N-R-I-I-E-E-A-N-Q-L-R-E-E-N-I-Q-P-I-E-D-L-I-Y-S-S-G-S-G-L-D-P-H-I-S-I-Q-A-A-S-Q-Q-I-E-R-V-A-R-A-R-N-V-Q-P-D-E-I-L-R-L-M-N-K-Y-T-D-G-R-F-L-W-I-F-G-E-P-G-V-N-V-L-R-L-N-Y-A-L-D-L-Q-D-F-N-N-Q-Q-N-R"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-N-I-E-D-R-V-R-K-I-I-I-E-Q-L-G-V-D-E-A-E-V-K-N-E-A-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-T-E-I-P-D-E-A-A-E-K-I-T-T-V-Q-A-A-I-D-Y-V-N-S-A-S-E"} +{"text": "### FUNCTION Required for growth utilizing PHB cycle intermediates ### SEQUENCE -M-R-L-T-K-Q-T-N-Y-A-V-R-M-L-M-Y-C-A-A-N-G-E-K-L-S-R-I-P-E-I-A-R-A-Y-G-V-S-E-L-F-L-F-K-I-L-Q-P-L-T-R-A-G-L-V-E-T-V-R-G-R-N-G-G-V-R-L-P-R-P-A-S-E-I-T-L-F-D-V-V-K-V-T-E-D-S-F-A-M-A-E-C-F-E-A-G-E-I-D-C-P-L-V-D-S-C-G-L-N-A-A-L-R-K-A-L-N-A-F-F-E-V-L-Q-G-Y-T-I-D-D-L-V-K-A-R-P-Q-I-N-F-L-L-G-L-E-E-P-V-R-P-Q-T-S-A-A"} +{"text": "### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-Y-S-C-I-T-F-F-Q-R-L-E-R-S-I-L-S-G-N-K-T-A-T-I-R-D-K-S-D-S-H-Y-L-V-G-Q-M-L-D-A-C-T-H-E-D-N-R-K-M-C-Q-I-E-I-L-S-I-E-Y-V-T-F-S-E-L-N-R-A-H-A-N-A-E-G-L-P-F-L-F-M-L-K-W-I-V-R-K-I-Y-P-T-S-N-D-L-F-F-I-S-F-R-V-V-T-I-D-I-L"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-K-T-A-Y-D-V-I-L-A-P-V-L-S-E-K-A-Y-A-G-F-A-E-G-K-Y-T-F-W-V-H-P-K-A-T-K-T-E-I-K-N-A-V-E-T-A-F-K-V-K-V-V-K-V-N-T-L-H-V-R-G-K-K-K-R-L-G-R-Y-L-G-K-R-P-D-R-K-K-A-I-V-Q-V-A-P-G-Q-K-I-E-A-L-E-G-L-I"} +{"text": "### FUNCTION Transcriptional repressor for the dhaA haloalkane dehalogenase gene ### SEQUENCE -M-A-R-T-P-V-R-Q-H-L-V-E-K-G-T-Q-V-F-L-E-R-G-Y-S-G-S-A-V-Q-D-I-T-A-A-A-E-V-P-K-G-S-F-Y-N-H-F-E-S-K-E-A-F-G-G-Q-V-L-Q-E-F-F-S-D-L-Q-R-T-I-S-S-T-L-E-D-A-S-V-P-P-V-R-R-L-Q-N-Y-F-A-A-I-I-E-T-L-D-G-Q-G-C-L-I-G-N-F-S-V-E-L-S-P-L-S-D-V-V-R-T-E-L-L-R-I-F-E-Q-W-V-K-P-F-Q-K-C-I-I-E-G-Q-E-T-G-S-I-R-R-D-L-A-P-D-L-L-A-D-F-L-I-A-S-W-Q-G-A-I-L-R-M-K-I-E-R-N-R-E-P-L-D-Q-F-L-T-V-V-F-E-A-L-L-P-S-T-E-N-I-S-N-E-S"} +{"text": "### FUNCTION N-acyltransferase required for nodulation Acts in the production of a small, heat-stable compound that stimulates mitosis in various plant protoplasts ### SEQUENCE -M-R-S-A-V-Q-W-R-L-C-W-E-N-D-L-Q-L-T-D-H-V-E-L-S-D-F-F-R-K-I-Y-G-R-I-G-S-F-D-A-K-P-F-E-G-G-R-S-W-A-G-A-R-P-E-V-R-L-I-A-S-D-A-Q-G-I-A-A-H-V-G-I-L-R-R-F-I-K-V-G-E-V-D-F-L-V-A-E-L-G-L-Y-G-V-R-P-D-L-E-K-L-G-I-S-F-S-M-R-M-V-H-P-V-L-Q-Q-L-A-V-P-F-A-F-G-T-V-R-H-A-M-R-S-H-V-E-R-F-C-R-E-G-I-A-A-I-V-P-G-V-K-V-R-S-S-R-A-N-V-H-H-D-L-P-S-T-R-L-E-D-V-I-V-L-V-S-P-I-G-R-S-I-D-E-W-P-P-G-D-V-I-D-R-N-G-S-E-L"} +{"text": "### FUNCTION Probably involved in host-pathogen interactions ### SEQUENCE -M-S-H-S-K-I-K-A-G-G-H-G-S-S-G-I-G-N-D-F-T-P-A-K-T-P-A-P-A-T-P-A-P-Q-S-Q-Q-V-N-D-L-L-G-R-G-V-G-N-A-L-N-K-S-N-L-G-S-D-S-Q-T-W-T-P-G-S-T-M-V-S-L-K-S-R-S-S-S-S-H-K-P-D-T-G-G-D-T-K-P-D-S-T-S-G-G-K-R-K-R-D-D-E-T-D-P-N-A-E-T-E-G-G-K-K-K-K-K-R-D-D-E-N-D-S-S-Q-A-G-G-A-G-S-S-A-G-S-S-G-S-P-E-D-A-L-M-N-I-A-L-Q-R-A-I-Q-R-Q-T-Q-T-R-Q-K-M-Q-E-A-M-K-I-K-D-D-D-D"} +{"text": "### FUNCTION Nitric oxide-responsive transcriptional regulator ### SEQUENCE -M-Q-L-T-S-Y-T-D-Y-S-L-R-L-L-L-Y-L-A-L-Q-P-K-D-K-L-S-S-V-K-Q-V-A-T-I-Y-N-I-S-Y-N-H-L-T-K-V-T-Y-E-L-G-K-L-G-L-I-E-T-I-K-G-R-N-G-G-I-R-L-A-K-A-P-E-E-I-N-I-G-A-V-V-K-Q-T-E-D-N-L-E-L-V-E-C-F-N-H-E-T-N-T-C-I-L-N-P-V-C-R-L-K-G-V-L-H-E-A-L-T-A-Y-L-R-V-L-E-Q-Y-T-L-K-D-L-L-T-N-E-D-E-L-Q-A-L-L-K-L-K-P"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-E-H-R-I-K-R-S-D-E-F-S-R-V-F-N-E-G-F-S-V-A-N-R-Q-F-V-I-Y-V-L-P-K-E-G-Q-D-F-F-R-V-G-L-S-V-S-K-K-I-G-N-A-V-T-R-N-R-V-K-R-L-I-R-T-F-F-Q-E-H-E-Q-A-I-S-G-E-R-D-Y-V-I-I-A-R-K-P-A-A-D-M-T-Y-E-Q-V-K-G-S-L-W-H-V-C-K-K-A-K-I-I-Q-P-K-V-R-A-H-K"} +{"text": "### FUNCTION Component of the thioredoxin-thioredoxin reductase system Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-T-S-T-V-E-L-T-K-E-N-F-D-Q-T-V-T-D-N-E-F-V-L-I-D-F-W-A-E-W-C-G-P-C-K-Q-F-G-P-V-Y-E-K-A-A-E-A-N-P-D-L-V-F-G-K-V-D-T-E-A-Q-P-E-L-A-Q-A-F-G-I-S-S-I-P-T-L-M-I-V-R-E-Q-V-A-V-F-A-Q-P-G-A-L-P-E-A-A-L-T-D-V-I-G-Q-A-R-K-L-D-M-D-E-V-R-K-A-V-A-E-Q-Q-A-Q-A-G-Q-N-G-Q-E-G-Q-E-G-Q"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-I-K-R-N-K-T-N-E-K-A-R-L-R-N-K-S-V-K-S-S-L-K-T-A-I-R-K-A-R-E-A-A-A-A-G-D-V-E-K-A-T-E-F-Q-R-V-A-S-R-E-L-D-K-A-V-S-K-G-V-I-H-K-N-Q-A-A-N-K-K-S-A-L-A-Q-K-V-G-A-L-K-G"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-K-L-N-K-Q-N-I-I-N-H-V-N-N-L-Q-L-K-K-S-V-P-N-F-Q-V-G-D-T-V-S-V-S-I-K-I-A-D-E-K-R-T-R-I-Q-K-F-D-G-L-V-L-R-R-K-G-S-G-L-S-E-T-F-I-V-R-K-E-S-S-G-V-G-V-E-K-N-F-H-V-H-N-P-N-I-E-I-E-L-K-R-K-G-K-V-R-R-A-Y-I-S-Y-M-R-E-R-S-G-K-S-A-R-I-K-E-K-V-V-N-T-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-K-K-K-T-V-A-S-N-G-I-A-H-I-H-A-T-S-N-N-S-I-I-T-I-T-D-I-N-G-N-A-I-T-W-S-S-S-G-A-I-G-Y-K-G-A-K-K-K-T-P-Y-S-A-G-V-A-A-E-K-A-A-K-E-A-M-A-M-G-L-S-T-I-K-I-Y-V-N-G-V-G-R-G-K-E-T-A-I-R-S-L-A-A-C-G-L-T-I-T-E-I-H-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-P-R"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-L-G-I-D-I-P-N-N-K-R-V-E-I-S-L-T-Y-I-Y-G-I-G-K-P-R-A-Q-E-I-L-R-K-A-K-I-D-F-N-K-R-V-K-D-L-S-D-E-E-L-A-L-I-R-S-V-A-S-T-Y-V-L-E-G-D-L-R-R-D-V-A-L-N-I-K-R-L-M-E-V-G-S-Y-A-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-S-N-A-R-T-R-K-G-P-R-K-T-V-A-N-K-K-I-E-S-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-I-E-I-C-K-K-L-H-V-L-I-V-E-A-R-F-Y-D-G-I-S-D-A-L-L-T-G-A-V-S-T-L-Q-K-A-E-A-T-Y-D-I-V-T-V-P-G-A-L-E-I-P-G-A-I-A-F-A-E-K-N-S-K-I-Y-Y-D-G-Y-V-A-L-G-C-V-I-R-G-E-T-Y-H-F-E-I-V-A-N-D-S-C-R-A-L-M-D-L-T-I-H-K-H-L-A-I-G-N-G-I-L-T-V-E-N-E-K-Q-A-W-A-R-A-K-Q-D-E-K-N-K-G-G-F-A-A-Q-A-A-L-C-M-I-A-L-K-K-R-F-G-E-I-I-K-Y-G"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-M-S-L-C-E-G-I-R-G-I-V-E-D-Q-A-R-R-H-G-F-A-T-V-K-V-L-R-L-E-I-G-R-F-A-G-V-E-K-A-A-L-G-F-A-F-D-V-V-M-R-G-S-A-A-E-G-A-R-L-E-I-L-E-L-P-G-R-A-L-C-Y-D-C-G-E-E-A-A-I-Q-D-R-F-D-P-C-P-L-C-G-G-G-R-L-M-P-V-G-G-D-E-M-R-I-K-D-M-E-V-Q"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-L-L-P-I-L-E-V-P-D-P-R-L-R-E-K-S-T-V-V-E-V-F-D-D-N-L-Q-R-L-I-D-D-M-F-E-T-M-Y-K-A-P-G-I-G-L-A-A-I-Q-V-G-V-A-K-R-L-L-V-I-D-L-Q-Q-P-E-E-G-G-E-A-K-R-N-P-M-V-F-I-N-P-E-L-T-P-E-G-E-E-K-R-L-Y-N-E-G-C-L-S-V-P-D-Q-Y-A-E-V-R-R-P-S-V-I-N-A-K-W-Q-D-R-D-G-N-F-H-E-E-R-I-E-G-L-L-A-T-C-L-Q-H-E-M-D-H-L-E-G-I-L-F-I-D-H-L-S-R-L-K-R-G-M-L-M-K-K-L-L-K-E-R-K-L-R-E-D-S-Y"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-P-P-A-E-L-P-P-E-E-R-Y-K-K-A-K-E-I-C-F-D-L-L-A-V-R-A-R-T-Q-E-E-L-R-Q-A-L-R-R-K-G-F-D-E-E-T-S-E-T-L-L-G-K-L-D-R-A-G-L-V-N-D-A-E-F-A-E-L-W-V-K-S-R-H-T-T-Q-G-L-S-R-T-A-L-M-A-E-L-R-R-K-G-V-D-D-E-V-A-A-Q-A-A-G-E-V-D-R-E-S-E-E-Q-M-A-R-E-L-V-R-K-R-L-G-S-L-G-N-V-D-E-Q-T-A-L-R-R-L-L-G-F-L-A-R-K-G-Y-P-Q-G-L-A-Y-T-V-I-K-E-E-L-R-E-Y-G-A-E-S-T-L-L-D-D-A-V-I-D"} +{"text": "### FUNCTION Catalyzes the decarboxylation of oxaloacetate coupled to Na translocation ### SEQUENCE -M-T-N-A-E-L-F-G-E-G-I-N-L-M-I-A-G-M-G-F-V-M-F-F-L-I-I-L-I-Y-A-I-S-V-I-S-R-L-I-N-K-Y-F-P-D-P-T-Q-T-P-P-A-Q-P-I-P-A-V-I-P-P-T-D-L-E-R-L-R-P-V-I-V-A-A-I-A-H-H-R-R-Q-Q-R-S-N"} +{"text": "### FUNCTION Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence Negatively regulates the transcription of several known virulence factors such as lipase Also, modulates the expression of genes not previously implicated in pathogenesis ### SEQUENCE -M-H-K-L-A-H-T-S-F-G-I-V-G-M-F-V-N-T-C-I-V-A-K-Y-V-I-I-N-W-E-M-F-S-M-K-K-V-N-N-D-T-V-F-G-I-L-Q-L-E-T-L-L-G-D-I-N-S-I-F-S-E-I-E-S-E-Y-K-M-S-R-E-E-I-L-I-L-L-T-L-W-Q-K-G-S-M-T-L-K-E-M-D-R-F-V-E-V-K-P-Y-K-R-T-R-T-Y-N-N-L-V-E-L-E-W-I-Y-K-E-R-P-V-D-D-E-R-T-V-I-I-H-F-N-E-K-L-Q-Q-E-K-V-E-L-L-N-F-I-S-D-A-I-A-S-R-A-T-A-M-Q-N-S-L-N-A-I-I-A-V"} +{"text": "### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-T-L-Y-T-S-P-S-C-T-S-C-R-K-A-R-A-W-L-E-E-H-D-I-P-Y-K-E-R-N-I-F-S-E-P-L-S-L-D-E-I-K-E-I-L-R-M-T-E-D-G-T-D-E-I-I-S-T-R-S-K-T-F-Q-K-L-N-V-D-L-D-S-L-P-L-Q-Q-L-F-E-L-I-Q-K-N-P-G-L-L-R-R-P-I-I-I-D-E-K-R-L-Q-V-G-Y-N-E-D-E-I-R-R-F-L-P-R-R-V-R-T-Y-Q-L-R-E-A-Q-K-M-V-N"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-D-N-L-E-Y-R-S-G-V-G-I-M-L-L-N-K-D-N-L-V-F-A-A-C-R-N-D-M-K-E-E-A-W-Q-M-P-Q-G-G-L-E-A-K-E-T-P-E-V-G-V-L-R-E-L-E-E-E-T-G-I-P-P-R-M-V-A-I-I-S-H-T-K-E-W-L-T-Y-D-F-P-A-D-L-Q-A-S-F-F-K-N-K-Y-R-G-Q-R-Q-L-W-F-L-A-R-Y-L-G-R-D-E-D-I-N-I-N-T-D-K-P-E-F-R-A-W-K-W-V-E-P-K-Q-L-P-D-L-I-V-A-F-K-K-P-L-Y-E-K-I-L-S-E-F-S-A-S-L"} +{"text": "### FUNCTION Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition GvpA forms the protein shell ### SEQUENCE -M-A-V-E-K-I-N-A-S-S-S-L-A-E-V-V-D-R-I-L-D-K-G-V-V-V-D-A-W-V-R-V-S-L-V-G-I-E-L-L-A-V-E-A-R-V-V-V-A-G-V-D-T-Y-L-K-Y-A-E-A-V-G-L-T-A-S-A-Q-A-A"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-D-K-N-E-R-P-I-K-V-M-A-E-N-R-K-A-R-F-N-Y-A-I-E-D-T-I-E-A-G-I-A-L-T-G-T-E-V-K-S-I-R-N-G-K-S-T-I-A-E-S-Y-A-D-S-K-N-G-E-I-W-L-I-N-A-T-I-P-E-Y-L-Q-G-N-R-F-N-H-E-P-K-R-P-R-K-L-L-L-H-R-R-Q-I-N-K-L-I-G-A-V-D-R-E-G-M-T-L-I-P-L-K-L-Y-F-N-E-R-G-R-A-K-L-Q-L-A-V-A-K-G-K-K-L-H-D-K-R-E-T-E-K-K-R-D-W-S-R-E-K-G-R-L-L-R-A-R-G"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-I-T-A-I-D-T-N-I-Y-D-Q-P-E-F-V-E-G-R-D-V-I-G-V-R-F-E-D-L-V-L-D-K-R-I-Q-R-V-A-L-P-G-G-E-E-L-G-L-R-L-N-H-G-H-P-I-L-R-E-G-D-V-L-K-A-D-D-K-T-V-F-V-V-E-I-I-P-T-D-V-L-V-I-T-P-S-D-I-H-Q-M-G-F-V-A-H-S-L-G-N-R-H-L-P-A-Q-F-S-K-P-G-E-L-T-E-K-A-A-M-I-V-Q-Y-D-H-T-V-V-S-F-L-D-E-H-G-I-E-Y-Q-R-T-E-L-V-P-P-I-P-F-R-H-S-G-H-T-H"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-F-G-R-L-G-A-P-E-I-I-L-I-L-V-V-I-I-L-L-F-G-A-K-K-L-P-D-M-A-R-S-L-G-K-S-A-R-I-L-K-S-E-A-K-A-M-K-S-E-A-K-A-D-D-A-A-P-A-D-P-P-N-P-E-Q-S-A-A-Q-R-T-I-Q-A-A-P-G-D-V-T-S-S-R-P-V-T-E-P-T-D-T-T-K-R"} +{"text": "### FUNCTION Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms They allow the positioning of the organism at the favorable depth for growth This protein could be important for the shape determination of the gas vesicle ### SEQUENCE -M-T-D-L-D-H-R-Y-P-G-E-E-T-E-P-Y-G-P-P-S-G-S-L-A-D-L-L-E-R-V-L-D-K-G-I-V-I-A-G-D-I-K-I-D-L-L-D-I-E-L-L-T-I-R-L-R-L-F-I-A-S-V-D-T-A-K-K-A-G-I-D-W-W-E-T-D-P-A-L-S-S-R-A-A-R-D-A-L-A-E-E-N-A-R-L-R-E-R-L-D-A-L-E-G-A-A-G-E-T-T-G-A-V-R"} +{"text": "### FUNCTION Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition GvpA forms the protein shell ### SEQUENCE -M-I-T-Y-D-D-E-V-V-C-A-P-R-A-G-T-L-Y-D-V-L-E-L-I-L-D-R-G-M-V-I-D-V-F-V-R-V-S-L-V-G-I-E-I-L-K-V-D-A-R-I-V-V-A-S-V-D-T-Y-L-R-F-A-E-A-C-N-R-L-D-L-E-H-D-V-R-S-K-T-V-P-E-M-F-G-S-P-M-A-K-T-V-G-R-A-G-A-R-R-T-A-R-S-L-T-D-K-V-R-D-V-L-T-P-E-H-E-H-E-E-E-P-E-E-A-E-D-R-P-R-A-G-A-E-R-G-R-S-T-Q-R-P-R-S-R-P-A-A-R-P-R-D-E-D-D-R-P-R-S-R-P-R-R-R-T-E-E-E-D-R"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-P-S-T-A-D-E-R-Q-L-L-D-E-L-R-D-L-L-A-A-T-V-E-D-L-T-V-E-E-I-G-P-D-S-S-L-Q-D-D-L-G-V-D-S-L-A-R-L-E-L-V-A-A-I-E-D-R-W-Q-I-E-V-P-Q-E-Q-A-D-R-L-T-T-V-R-Q-I-A-A-H-L-A-E-A-V-A-A-P-A-G-G-T-A"} +{"text": "### FUNCTION May nick NmeDI sequences that contain T/G mispairs resulting from m5C-deamination If unrepaired, these mismatches can lead to C-to-T transition mutations The very short patch repair process counteracts the mutagenic process by repairing the mismatches in favor of the G-containing strand This enzyme is an endonuclease that nicks double-stranded DNA within the sequence RTCGGB next to the thymidine residue that is mismatched to 2'-deoxyguanosine The incision is mismatch-dependent and strand-specific ### SEQUENCE -M-D-R-L-T-P-E-Q-R-K-K-C-M-Q-S-N-K-S-K-G-T-K-P-E-L-A-L-A-K-A-M-W-A-L-G-L-R-Y-R-K-N-S-G-S-I-F-G-K-P-D-F-S-F-K-K-Y-K-V-A-V-F-V-D-G-E-F-W-H-G-K-D-W-E-Q-R-K-A-E-I-K-G-N-R-E-F-W-I-A-K-I-E-R-N-I-R-R-D-M-E-V-T-G-R-L-K-V-E-G-W-A-V-L-R-F-W-S-N-D-V-V-K-N-T-T-C-C-A-E-K-V-R-Q-A-V-R-D-K-Q-G-L-S-K-F-Q-T-R-E-K"} +{"text": "### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-E-I-R-K-S-A-V-A-G-T-L-E-S-S-D-V-Q-I-M-L-S-A-G-N-N-G-I-E-F-E-L-V-S-D-V-A-K-Q-F-G-D-A-I-K-E-T-I-T-D-V-L-N-T-Y-G-V-T-D-A-A-V-S-V-V-D-K-G-A-L-D-M-V-I-R-A-R-A-I-A-V-V-Q-R-A-L-D-I-V-D-T-P-N-W-E-V-L"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-S-Y-T-H-I-L-V-A-V-A-V-T-P-E-S-H-Q-L-L-A-K-A-V-S-I-A-R-P-V-Q-A-K-V-S-L-I-T-L-A-S-D-P-E-L-Y-N-Q-F-A-A-P-M-M-E-D-L-R-A-V-M-H-E-E-T-E-N-F-L-K-M-L-G-E-K-A-D-Y-P-I-E-Q-T-F-I-A-S-G-E-L-S-Q-H-I-L-A-V-C-R-K-H-H-V-D-L-V-I-C-G-N-H-N-H-S-F-F-S-R-A-S-C-S-A-K-S-V-V-S-A-S-Q-V-D-V-L-L-V-P-L-A-G-D"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-S-Q-E-K-N-I-S-E-L-S-F-E-E-A-L-K-K-L-E-E-I-V-R-R-L-E-S-G-D-T-T-L-E-D-S-I-Q-M-Y-S-Q-G-D-A-L-K-K-Q-C-E-A-R-L-K-A-A-Q-K-K-I-E-Q-I-S-L-D-Q-D-G-R-A-T-G-T-S-P-F-D-A-E"} +{"text": "### FUNCTION Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates ### SEQUENCE -M-A-F-S-T-Q-D-S-D-E-V-L-S-E-I-N-V-T-P-L-V-D-V-M-L-V-L-L-V-V-F-I-V-T-A-P-L-L-T-N-S-I-P-I-N-L-P-K-T-E-S-V-A-P-P-E-Q-K-D-P-L-V-V-S-I-D-G-A-G-K-L-F-V-N-K-D-E-I-Q-P-E-L-L-E-S-N-L-A-A-A-K-A-K-D-A-E-V-R-V-Q-L-Q-A-D-E-G-V-N-Y-G-Q-V-A-K-A-M-A-S-I-E-R-A-G-I-T-R-L-A-V-I-T-A-R"} +{"text": "### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-Q-A-D-I-P-T-L-T-R-A-D-I-T-D-M-L-Y-H-E-V-G-L-S-R-A-D-S-A-K-M-I-E-Q-M-L-G-H-I-T-D-A-L-K-K-G-E-N-V-K-I-S-G-F-G-S-F-I-L-R-D-K-N-E-R-V-G-R-N-P-K-T-G-I-E-V-P-I-A-P-R-R-V-L-T-F-R-A-S-Q-L-M-R-Q-R-I-I-K-G-A"} +{"text": "### FUNCTION Catalyzes the hydrolysis of methenyl-HMPT ### SEQUENCE -S-L-S-H-G-K-Y-Y-A-L-G-S-G-P-A-R-A-M-A-T-K-V-K-D-G-A-V-E-P-V-E-E-L-Y-K-E-L-E-Y-R-D-S-H-D-K-T-V-L-V-I-E-N-D-A-V-P-P-V-E-I-V-E-K-V-A-A-A-C-G-V-S-P-A-D-L-T-I-I-V-T-P-T-S-S-L-A-G-G-V-Q-V-V-G-R-V-L-E-V-A-M-H-K-A-H-A-L-H-F-P-L-E-N-I-V-D-G-T-G-S-A-P-V-C-P-P-H-P-N-F-V-K-A"} +{"text": "### FUNCTION Catalyzes the hydrolysis of methenyl-HMPT ### SEQUENCE -S-L-S-H-G-E-G-K-N-A-F-Y-A-L-G-S-G-P-A-R-A-L-A-T-K-V-K-D-G-N-E-E-P-V-E-E-L-Y-K-E-L-G-Y-R-D-H-S-N-E-T-A-I-V-M-E-V-D-K-V-P-P-V-E-V-I-E-K-I-A-K-A-C-K-V-D-A-S-G-V-H-V-I-L-T-P-T-S-S-L-A-G-G-M-Q-V-V-G-R-V-L-E-V-A-L-H-K-A-H-S-L-H-F-P-L-G-N-I-I-D-G-T-G-T-A-P-V-P-P-P-H-P-N-F-V-K-A"} +{"text": "### FUNCTION Catalyzes the hydrolysis of methenyl-HMPT ### SEQUENCE -S-L-S-H-E-K-Y-Y-A-L-G-S-G-P-A-R-A-M-A-A-K-I-K-D-G-N-E-E-P-V-E-E-L-Y-K-E-L-G-Y-R-D-S-F-D-S-T-V-L-V-I-E-N-D-A-V-P-P-P-A-I-V-E-K-V-A-A-A-C-K-V-D-P-G-K-L-T-V-I-V-T-P-T-S-S-L-A-G-G-L-Q-V-V-A-R-V-L-E-V-A-M-H-K-A-H-A-L-H-F-P-L-E-N-I-V-D-G-F-G-S-A-P-L-C-P-P-H-P-N-F-V-K-A"} +{"text": "### FUNCTION Catalyzes the hydrolysis of methenyl-HMPT ### SEQUENCE -S-L-S-H-E-K-F-F-S-L-G-S-G-P-G-R-A-L-A-G-R-E-E-L-Y-K-E-L-G-Y-K-D-S-A-D-A-A-V-L-V-L-E-S-D-K-V-P-P-Q-E-V-V-E-K-V-A-R-D-T-G-V-K-A-E-N-L-T-F-I-L-T-P-T-R-S-L-A-G-T-V-Q-I-V-A-R-V-L-E-V-A-L-H-K-I-H-T-L-H-F-P-L-E-H-V-V-D-G-M-A-S-A-P-L-P-P-P-A-P-D-F-L-I-G-M-G-R-T-N-D-A-I-L-F-G-G-H-A-H-I-F-V-K-G-S-D-E-A-A-A-K-L-A-K-E-L-P-S-S-A-S-R-D-Y-G-R-P-F-A-E-V-F-K-A-V-N-M"} +{"text": "### FUNCTION Catalyzes the hydrolysis of methenyl-HMPT ### SEQUENCE -T-I-T-E-E-T-T-G-F-F-A-L-G-S-G-P-A-R-A-L-S-R-V-E-D-L-F-K-E-L-N-Y-A-D-Q-G-P-N-T-A-L-V-I-E-G-D-K-A-P-P-A-A-V-I-E-N-I-A-K-H-C-G-I-N-P-K-G-L-S-I-L-Y-A-T-T-W-S-L-A-G-T-V-Q-I-A-A-R-V-L-E-V-A-M-H-K-A-H-A-L-H-F-A-L-E-N-I-I-D-G-T-A-T-T-P-I-A-P-P-F-P-D-F-V-K-A-M-G-R-T-N-D-A-I-I-Y-G-G-R-A-H-L-F-V-K-G-T-D-A-E-A-K-R-L-A-E-G-L-P-S-S-T-C-A-S-F-G-K-P-F-A-E-I-F-A-D-V-N-G"} +{"text": "### FUNCTION The VirB system could be required for the establishment of the replication niche in the host ### SEQUENCE -M-R-T-L-V-M-V-A-C-A-V-S-L-A-A-C-S-S-P-P-K-P-P-T-V-S-G-R-H-R-I-P-I-N-S-P-A-A-Q-E-E-L-R-L-Q-V-F-P-Q-E-P-T-A-Q-A-T-M-W-P-A-R-P-P-K-Q-T-V-S-V-Y-F-P-Q-D-V-T-V-F-R-P-T-S-A-Q-I-N-Q-L-H-T-L-L-W-P-V-P-K-H-I-N-V-R-G-L-T-D-N-N-C-P-P-P-G-D-T-Q-V-A-R-V-R-A-L-A-I-Y-N-W-L-I-N-Q-G-V-S-A-S-R-I-T-I-S-Y-A-P-V-K-D-Y-A-S-N-A-P-L-S-P-G-R-V-L-N-R-R-V-D-I-E-I-L-R-K"} +{"text": "### FUNCTION Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins May act as a hydrogen peroxide and organic hydroperoxide sensor ### SEQUENCE -M-S-V-E-I-E-S-I-E-H-E-L-E-E-S-I-A-S-L-R-Q-A-G-V-R-I-T-P-Q-R-Q-A-I-L-R-Y-L-I-S-S-H-T-H-P-T-A-D-E-I-Y-Q-A-L-S-P-D-F-P-N-I-S-V-A-T-I-Y-N-N-L-R-V-F-K-D-I-G-I-V-K-E-L-T-Y-G-D-S-S-S-R-F-D-F-N-T-H-N-H-Y-H-I-I-C-E-Q-C-G-K-I-V-D-F-Q-Y-P-Q-L-N-E-I-E-R-L-A-Q-H-M-T-D-F-D-V-T-H-H-R-M-E-I-Y-G-V-C-K-E-C-Q-D-K"} +{"text": "### FUNCTION Necessary for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine ### SEQUENCE -M-V-K-P-R-Q-R-E-Y-P-T-L-K-S-S-L-N-I-V-R-E-T-A-L-I-A-I-S-C-V-F-W-I-Y-C-L-V-V-L-L-V-Y-I-G-T-I-F-E-I-H-D-E-S-I-N-T-I-R-V-A-L-N-I-E-N-T-E-I-L-D-I-F-E-T-M-G-I-F-A-I-I-I-F-V-F-F-T-I-S-I-L-I-Q-K-W-Q-R-G-R-E-S"} +{"text": "### FUNCTION Represses transcription of the icaADBC operon necessary for biofilm production ### SEQUENCE -M-K-D-K-I-I-D-N-A-I-T-L-F-S-E-K-G-Y-D-G-T-T-L-D-D-I-A-K-S-V-N-I-K-K-A-S-L-Y-Y-H-F-D-S-K-K-S-I-Y-E-Q-S-V-K-C-C-F-D-Y-L-N-N-I-I-M-M-N-Q-N-K-S-N-Y-S-I-D-A-L-Y-Q-F-L-F-E-F-I-F-D-I-E-E-R-Y-I-R-M-Y-V-Q-L-S-N-T-P-E-E-F-S-G-N-I-Y-G-Q-I-Q-D-L-N-Q-S-L-S-K-E-I-A-K-F-Y-D-E-S-K-I-K-M-T-K-E-D-F-Q-N-L-I-L-L-F-L-E-S-W-Y-L-K-A-S-F-S-Q-K-F-G-A-V-E-E-S-K-S-Q-F-K-D-E-V-Y-S-L-L-N-I-F-L-K-K"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-Y-G-I-G-T-D-I-V-S-L-K-R-I-V-R-L-S-K-K-F-G-Q-A-F-A-E-R-I-L-T-P-E-E-L-L-E-F-P-Q-A-G-K-P-V-N-Y-L-A-K-R-F-A-A-K-E-A-F-A-K-A-V-G-T-G-I-R-G-A-V-S-F-R-N-I-G-I-G-H-D-A-L-G-K-P-E-F-F-Y-A-P-A-L-S-K-W-L-E-E-Q-G-I-S-R-V-S-L-S-M-S-D-E-E-D-T-V-L-A-F-A-V-A-E-K"} +{"text": "### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates ### SEQUENCE -R-T-V-G-E-L-I-Q-N-Q-I-R-V-G-L-S-R-M-E-R-V-V-R-E-R-M-T-T-Q-D-V-E-A-I-T-P-Q-T-L-I-N-I-R-P-V-V-A-A-I-K-E-F-F-G-T-S-Q-L-S-Q-F-M-D-Q-N-N-P-L-S-G-L-T-H-K-R-R-L-S-A-L-G-P-G-G-L-S-R-E-R-A-G-L-E-V-R-D-V-H-S-S-H"} +{"text": "### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-S-D-A-P-S-G-P-P-R-L-V-V-G-V-S-G-G-S-G-I-P-Y-A-L-D-I-L-R-A-L-R-G-L-D-V-E-T-H-L-V-V-S-S-G-A-K-R-V-M-S-A-E-G-G-P-Q-L-A-D-L-T-A-L-A-S-V-V-H-D-D-R-D-L-A-A-A-V-A-S-G-S-Y-R-T-G-G-M-L-I-V-P-C-S-A-G-T-L-A-K-V-A-H-G-F-A-D-N-L-I-S-R-A-A-H-V-T-L-K-E-R-R-P-L-V-L-V-V-R-E-D-P-M-P-R-P-M-L-Q-N-M-L-A-A-H-D-A-G-A-T-V-M-S-A-S-P-G-F-Y-H-A-P-E-S-L-G-E-L-L-G-F-V-T-A-R-V-L-D-Q-F-G-L-N-A-P-G-F-R-R-W-R-E-D-E-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-A-A-P-L-V-R-A-V-R-W-Y-Q-R-V-L-S-P-R-K-P-A-P-T-C-R-F-S-P-T-C-S-E-Y-A-A-Q-A-L-D-R-H-G-A-L-K-G-G-W-L-A-L-W-R-V-L-R-C-N-P-L-V-P-G-G-F-D-P-V-P-E-H-F-P-A-R-H-P-R-P-Q-G-S-P-P-T-D-H-P-P-T-D-Q-P-S"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-P-T-K-G-K-A-P-R-R-S-R-R-N-I-S-A-G-R-A-Y-V-H-A-S-Y-N-N-T-I-V-T-I-T-D-L-D-G-N-S-V-A-W-S-S-G-G-T-I-G-Y-K-G-S-K-K-G-T-P-Y-A-A-Q-L-A-A-A-D-A-V-K-K-A-Q-T-S-F-G-M-A-A-V-D-V-I-V-R-G-S-G-S-G-R-E-Q-A-I-R-A-I-Q-A-S-G-I-E-V-R-S-I-M-D-D-S-P-V-P-H-N-G-C-R-P-K-K-K-F-R-A"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-D-L-P-R-E-K-R-V-E-I-A-L-T-Y-I-Y-G-I-G-L-T-R-S-K-E-I-L-A-R-T-G-V-S-P-D-T-R-V-K-N-L-S-E-A-E-Q-S-T-L-R-E-A-I-E-K-T-Y-K-V-E-G-D-L-R-N-E-V-G-Q-N-I-K-R-L-M-D-I-G-A-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-K-K-T-V-A-G-K-K-K-A-T-R-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-P-E-Q-R-E-K-K-K-K-D-E-S-D-S-V-R-A-E-G-V-V-E-E-A-L-P-N-T-T-F-R-V-K-L-D-T-G-H-D-I-L-A-Y-I-S-G-K-M-R-I-H-Y-I-R-I-L-P-G-D-R-V-V-L-E-I-S-P-Y-D-T-S-R-G-R-I-V-Y-R-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-L-S-D-P-I-A-D-M-L-T-R-I-R-N-A-T-R-T-H-K-E-T-V-D-I-P-A-S-K-F-K-E-E-L-A-K-L-L-V-R-E-G-Y-V-Q-G-V-E-R-T-R-P-E-G-Q-K-F-D-V-L-R-V-T-L-K-Y-G-E-K-R-E-Q-V-I-K-H-I-E-R-V-S-R-P-G-R-R-A-Y-V-S-A-E-N-L-P-R-V-Q-R-G-L-G-V-A-V-V-S-T-S-R-G-L-L-P-D-R-E-A-R-Q-Q-G-V-G-G-E-V-V-C-V-L-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-N-K-S-K-L-A-K-Q-K-Q-R-E-K-T-V-E-K-Y-A-A-K-R-A-E-L-K-A-A-G-D-Y-Y-G-L-T-Q-L-P-R-D-A-S-P-T-R-L-H-N-R-C-E-F-T-G-R-P-R-G-Y-V-R-F-F-G-V-S-R-I-V-L-R-E-M-A-H-R-G-E-L-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-D-L-I-A-R-K-R-P-P-A-G-L-R-P-A-L-R-A-S-L-S-A-A-M-Q-H-F-G-G-E-E-R-E-V-T-V-V-L-V-G-D-P-E-I-R-A-L-K-L-E-H-W-G-E-D-A-A-T-D-V-L-S-F-P-T-W-E-P-G-D-P-F-M-P-P-H-L-G-D-I-I-I-S-L-D-T-A-Q-R-Q-A-E-S-R-G-H-S-L-T-R-E-V-A-L-L-A-S-H-G-L-T-H-L-V-G-H-D-H-P-H-A-E-G-L-G-F-E-E-G-A-T-G-E-D-W-Q-V-F-H-D-A-W-A-A-A-Q-T-G-L-P-A-G-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-T-R-R-R-E-K-A-V-Q-P-V-G-T-R-R-A-A-R-E-F-V-F-R-V-L-F-E-A-D-R-G-D-V-P-L-Q-A-V-F-T-R-A-E-G-V-M-R-E-G-D-D-T-F-P-Q-L-G-P-D-A-L-H-F-A-E-E-L-V-T-G-L-E-R-H-R-E-A-I-D-D-V-L-H-R-T-I-R-G-W-T-F-D-Q-M-A-Q-T-D-L-N-V-L-R-L-A-T-Y-E-L-M-Y-T-P-E-P-H-P-P-V-I-E-S-A-V-R-I-A-R-K-F-G-G-D-D-S-G-R-F-V-N-G-V-L-A-G-L-S-R-N-L-R-E-E-V-G-E-S-P-A-A-D-M-T-A-P-A-P-A-D-T-A-P-A-D-T-A-P-A-D-P-A-A-S-E-P-D-E-P-R-D-A"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-S-I-E-W-Y-A-V-H-T-Y-V-G-Q-E-D-R-V-Q-D-Q-L-M-D-R-A-R-R-L-G-M-Y-R-T-K-I-F-Q-V-L-Q-P-E-E-E-A-V-E-I-Q-E-G-G-K-K-V-N-V-K-R-K-L-F-P-G-Y-V-F-V-Q-M-D-V-E-D-D-D-A-P-G-E-L-G-E-S-W-E-V-V-R-G-T-S-G-V-T-G-F-V-G-T-A-T-R-P-V-P-L-S-P-E-E-V-Q-R-L-L-T-S-V-G-V-A-A-Q-P-V-V-E-E-A-P-R-I-K-V-D-L-K-A-G-D-M-V-R-V-T-S-G-P-F-A-D-F-S-G-V-V-S-E-V-N-A-P-Q-A-K-V-K-V-L-V-S-I-F-G-R-E-T-P-V-E-L-D-F-S-Q-V-A-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-K-K-V-A-G-I-V-K-L-Q-L-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-Y-G-A-N-I-M-E-F-T-K-A-F-N-A-Q-T-A-D-K-G-D-A-I-I-P-V-E-I-T-I-Y-A-D-R-S-F-T-F-I-T-K-T-P-P-M-S-Y-L-I-R-K-A-A-G-I-G-K-G-S-S-T-P-N-K-A-K-V-G-K-L-N-W-D-Q-V-L-E-I-A-K-T-K-M-P-D-L-N-A-G-S-V-E-A-A-A-N-T-V-A-G-T-A-R-S-M-G-V-T-V-E-G-G-P-N-A"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-Y-D-K-Q-A-L-I-D-Q-L-G-Q-L-T-I-M-E-L-A-D-L-I-D-G-L-K-E-T-W-G-V-T-A-A-V-A-V-S-G-G-G-A-G-A-A-S-P-A-A-E-E-K-T-E-F-D-V-V-L-I-D-A-G-A-S-K-I-N-V-I-K-E-I-R-G-I-T-G-L-G-L-K-E-A-K-D-M-S-E-K-G-G-V-L-K-E-G-V-A-K-D-E-A-E-K-M-K-A-Q-L-E-A-A-G-A-R-V-E-L-K"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-R-P-E-A-S-G-P-P-D-A-T-R-L-G-H-L-L-G-P-H-G-V-Q-G-G-I-K-L-Y-V-L-G-D-P-A-Q-V-L-A-L-K-R-V-Y-V-E-S-R-G-W-L-S-L-R-R-A-E-G-M-P-P-N-L-V-L-Y-L-A-G-V-S-S-R-E-G-A-E-E-L-R-G-L-Q-V-Y-A-T-D-A-E-L-P-D-L-E-E-G-T-F-Y-Y-H-D-L-R-G-L-E-V-Y-G-A-G-G-E-R-L-G-T-V-S-D-V-M-D-A-G-H-Q-D-L-L-V-V-D-Y-G-G-G-T-S-F-V-P-L-Q-A-P-Y-V-E-V-P-L-A-G-G-K-P-G-A-V-H-L-T-A-D-A-P-A-G-L-I-G-P-E-P-G-E-E-D-G-A-A-E-S"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-T-F-D-D-V-K-D-V-I-V-D-K-L-G-V-D-E-G-K-V-T-P-E-A-R-F-V-E-D-L-G-A-D-S-L-E-T-V-E-L-I-M-G-L-E-D-K-F-G-V-T-I-P-D-E-A-A-E-T-I-R-T-V-Q-A-A-V-D-Y-I-D-N-N-Q"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-T-T-T-P-T-D-R-K-Y-A-A-S-H-E-W-L-T-Q-D-G-T-V-G-I-S-D-H-A-Q-E-Q-L-G-D-V-V-Y-V-E-L-P-E-V-G-R-E-V-K-A-G-E-A-V-A-V-V-E-S-V-K-T-A-S-D-I-Y-A-P-A-S-G-T-I-T-A-V-N-D-E-L-S-G-S-P-E-K-V-N-E-S-P-Y-E-G-G-W-L-F-K-L-D-V-T-E-E-G-D-L-L-D-A-A-A-Y-E-A-Q-A-N"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-N-N-K-T-N-N-N-S-V-L-F-D-L-A-D-G-A-V-R-P-L-G-F-E-V-L-E-V-T-Q-Q-R-E-G-R-D-L-I-V-L-V-R-I-D-R-L-D-E-Q-P-V-T-M-D-D-L-T-A-A-S-R-A-A-E-A-E-F-D-R-V-D-P-I-E-E-E-Y-R-L-E-F-E-S-P-G-G-K-R-P-L-L-R-A-R-H-F-E-R-M-I-G-L-K-A-K-V-R-S-L-P-G-R-G-E-H-N-F-T-A-P-I-K-A-V-E-G-D-T-V-T-F-E-H-G-G-E-D-L-S-V-N-V-A-D-I-Q-A-S-L-A-E-F-P-D-R-H-R"} +{"text": "### FUNCTION Cell division inhibitor that blocks the formation of polar Z ring septums Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings Prevents FtsZ polymerization ### SEQUENCE -M-L-T-A-Q-I-T-V-E-I-Q-G-D-T-H-P-E-A-V-E-A-A-L-Q-G-V-R-E-A-G-G-T-L-G-R-V-R-A-P-R-L-T-V-N-M-P-A-S-V-A-A-E-P-V-T-S-A-Q-T-V-I-V-P-H-S-V-R-A-G-F-R-G-E-Y-R-G-S-V-V-V-L-G-D-V-N-P-G-A-E-L-I-A-A-G-D-V-I-V-A-G-A-L-R-G-V-V-H-A-G-Y-G-G-T-H-P-D-P-I-V-W-A-R-P-I-A-S-A-Q-I-R-I-G-D-A-V-A-R-A-P-E-G-S-S-N-M-R-R-T-D-R-T-E-R-A-E-R-A-Y-L-Q-D-G-M-I-V-I-D-V-Q"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-P-R-I-W-K-F-G-D-S-V-N-T-D-D-I-L-P-G-K-F-A-P-F-M-A-G-E-D-V-F-Q-T-F-A-F-H-Y-V-R-P-E-F-A-A-Q-V-Q-P-G-D-V-L-I-G-G-R-N-W-G-L-G-S-S-R-E-Y-A-P-Q-A-L-K-K-L-H-I-G-G-I-V-A-P-S-F-A-R-I-H-Y-R-N-L-L-N-L-G-I-P-A-F-E-Y-D-L-T-E-L-L-E-D-G-D-E-V-T-L-D-A-Q-T-G-L-L-T-Y-A-D-G-T-V-Q-L-P-P-P-P-E-F-L-R-E-A-L-K-E-G-S-I-L-E-F-F-K-K-H-G-R-F-P-G-E-E-P-G-A-E-A-S-T-E-T-A-S-A-A-E"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-D-M-K-S-I-Q-A-D-T-R-E-K-M-N-K-A-I-E-A-F-E-N-N-L-S-V-L-R-T-G-R-A-N-P-G-I-L-K-K-I-V-V-D-Y-Y-G-S-Q-M-P-I-D-Q-V-A-S-I-T-T-P-D-P-R-T-L-V-I-T-P-W-D-R-G-A-L-N-P-I-E-K-A-I-R-D-S-D-L-G-L-N-P-N-N-K-G-D-T-I-F-I-S-L-P-M-L-T-E-E-R-R-K-D-L-V-K-N-A-K-N-Y-A-E-D-A-R-I-A-V-R-N-L-R-K-H-A-L-D-E-V-K-K-V-E-G-L-G-E-D-E-I-K-R-G-E-A-D-V-Q-K-I-T-D-E-Y-V-A-R-V-E-S-V-F-Q-K-K-E-Q-E-I-L-G"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-R-R-V-Y-T-N-R-R-A-H-H-E-Y-E-L-L-E-R-F-E-A-G-I-S-L-T-G-S-E-V-K-S-V-R-A-G-G-V-D-F-R-D-A-F-A-R-I-N-G-S-D-V-D-L-E-G-L-Y-I-P-V-Y-K-E-A-T-Y-N-N-H-E-P-R-R-K-R-R-L-L-L-H-R-E-E-I-E-K-L-R-R-G-L-E-Q-K-G-L-T-L-V-P-T-R-L-Y-Q-K-G-R-Y-F-K-V-E-L-A-L-A-R-G-K-K-L-H-D-K-R-R-A-D-A-E-R-T-V-A-R-E-L-R-E-L"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-L-R-H-K-S-A-Q-K-R-H-R-Q-S-L-K-R-R-A-I-N-R-A-K-K-S-T-I-K-T-F-S-K-K-A-L-V-A-A-Q-G-G-A-E-D-A-T-A-M-Q-Q-R-A-E-S-L-I-D-K-A-A-K-G-S-T-L-H-K-N-A-A-A-R-K-K-S-R-L-A-K-A-I-N-K-A-K-A-A-Q-Q-A"} +{"text": "### FUNCTION Catalyzes the hydrolysis of 5-hydroxyisourate ### SEQUENCE -M-S-G-H-P-G-L-T-T-H-V-L-D-T-A-R-G-K-P-A-A-G-V-R-V-Q-L-C-R-V-T-G-D-T-R-T-P-V-T-E-A-V-T-N-S-D-G-R-T-D-A-P-L-I-E-R-G-S-L-K-Q-G-T-Y-E-L-T-F-H-V-A-D-Y-F-K-G-F-V-A-A-A-D-P-P-F-L-D-V-V-T-L-R-F-T-V-G-D-T-S-G-H-Y-H-V-P-L-V-M-T-P-W-S-Y-S-T-Y-R-G-S"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-T-A-P-K-A-T-I-L-S-S-D-E-I-R-R-A-L-T-R-I-A-H-E-I-I-E-R-N-K-G-A-E-N-L-A-I-I-G-V-H-T-R-G-I-P-L-A-E-R-L-A-S-K-L-S-E-L-E-G-V-E-V-P-R-G-M-L-D-I-T-L-Y-R-D-D-L-S-E-V-A-R-Q-P-I-I-R-E-T-Q-V-P-F-D-L-A-D-R-R-V-I-L-V-D-D-V-L-Y-T-G-R-T-V-R-A-A-L-D-A-L-I-D-L-G-R-P-E-G-I-Q-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-L-P-T-A-K-H-E-V-V-K-V-K-L-Q-E-T-D-G-T-D-I-V-E-L-F-D-P-E-D-L-Q"} +{"text": "### FUNCTION Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase ### SEQUENCE -M-Q-I-Y-Q-L-S-G-R-N-V-E-V-T-E-P-M-R-E-Y-V-E-E-K-L-S-R-L-D-R-Y-T-D-Q-I-T-D-A-R-V-T-L-T-V-R-D-V-R-N-N-E-R-R-N-R-V-E-V-Q-L-N-V-P-G-G-I-I-R-A-E-E-H-H-A-D-M-Y-A-A-I-D-K-A-S-D-V-L-E-R-Q-L-R-K-F-K-T-R-Y-M-K-Q-R-Q-E-G-R-P-E-P-L-P-G-P-A-E-A-E-V-N-A-Q-G-S-G-A-A-M-D-D-V-S-E-F-H-P-E-I-V-R-Q-K-R-F-E-L-R-P-M-S-A-E-D-A-V-V-Q-M-E-A-L-G-H-D-F-Y-V-F-Q-D-L-Q-G-Q-T-G-V-V-Y-R-R-R-D-G-H-Y-G-L-I-G-S-S"} +{"text": "### FUNCTION Possible metal-dependent hydrolase ### SEQUENCE -M-I-D-P-R-Y-P-L-G-P-M-P-Q-P-R-D-L-S-D-D-E-R-Q-E-A-R-A-A-L-R-A-L-P-G-E-L-R-A-A-V-A-G-L-S-E-P-Q-L-D-T-P-Y-R-E-G-G-W-T-V-R-Q-V-V-H-H-V-A-D-R-H-L-N-A-Y-V-H-T-A-R-V-L-S-G-G-E-A-L-A-Q-P-A-H-E-E-A-W-A-A-L-P-A-S-S-F-A-T-E-L-S-L-L-L-L-E-R-L-H-I-H-W-D-E-V-L-A-D-V-T-D-W-Q-Q-A-G-L-R-P-D-G-S-E-W-T-L-D-G-L-L-G-Q-A-A-W-H-G-R-H-H-T-A-H-I-T-R-L-R-E-R-E-G-W"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-V-P-F-R-A-L-R-C-R-D-E-V-A-V-F-F-L-A-A-P-G-P-L-M-K-P-E-Q-V-Q-A-Q-M-S-R-V-L-S-S-A-I-A-E-L-R-D-P-R-V-P-L-I-V-T-V-E-R-V-H-V-T-P-D-Y-G-Q-A-R-V-Y-V-S-A-I-G-A-D-M-P-E-L-L-D-A-L-T-H-A-R-G-R-L-Q-R-E-L-S-A-H-V-R-M-R-R-T-P-T-L-E-F-H-A-A-D-D-Q-R-F-P-A-A-P-G-S-T-W"} +{"text": "### FUNCTION Possible metal-dependent hydrolase ### SEQUENCE -M-S-D-P-R-Y-P-I-G-P-A-P-A-V-Q-T-L-T-H-E-Q-R-Q-E-R-L-A-H-L-A-A-L-P-E-E-F-E-A-A-F-A-G-L-S-D-A-Q-L-D-T-P-Y-R-E-G-G-W-T-L-R-Q-L-A-H-H-V-A-D-S-H-L-N-A-Y-V-R-T-K-L-A-L-T-E-D-R-P-T-V-K-T-Y-E-E-N-L-W-A-E-L-P-D-T-R-A-I-A-P-S-L-D-L-L-R-G-L-H-R-R-W-V-A-V-L-E-S-L-T-P-E-Q-W-A-R-V-F-V-H-P-V-S-G-P-N-T-L-D-T-M-L-A-Y-Y-T-W-H-G-Q-H-H-T-A-H-A-L-N-L-R-Q-E-R-G-W"} +{"text": "### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-N-R-D-T-R-L-Y-L-A-W-L-V-A-L-A-A-T-L-G-S-L-Y-F-S-E-I-R-H-F-N-P-C-P-L-C-W-A-Q-R-I-F-M-Y-P-L-A-V-I-L-G-I-A-A-F-V-G-D-H-G-V-R-R-Y-V-L-P-L-A-A-L-G-L-G-F-A-I-F-Q-N-L-E-T-W-G-F-V-Q-S-I-K-A-C-T-V-N-A-A-A-A-C-N-T-P-W-P-V-W-G-T-S-Q-D-T-L-N-R-A-L-T-I-P-V-L-S-M-I-A-F-A-L-I-L-A-L-L-S-W-P-R-Q-R-V-T-V-P-E-S-A-A-V-Q-G"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-F-G-W-F-K-G-R-R-S-K-E-T-L-K-D-R-L-E-L-V-L-A-Y-D-R-A-K-I-A-P-G-K-V-E-A-L-R-N-D-L-L-E-V-V-Q-K-Y-F-P-S-G-N-S-K-V-E-V-E-Q-D-G-D-K-V-V-L-M-A-S-I-S-I-E-E-A-S-L-S-T-E-E-E-S-A-A-E-D-K-S-D-K-P-S-A"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-L-G-K-E-I-G-K-D-Q-R-Q-K-R-I-Q-D-I-I-L-R-E-S-V-S-T-Q-A-E-L-V-K-L-L-A-K-E-G-V-Q-V-T-Q-A-T-V-S-R-D-I-N-E-L-R-L-V-R-V-P-I-G-K-G-R-H-R-Y-A-L-A-Q-Y-G-G-D-S-D-I-E-E-Q-L-A-R-L-F-Q-S-F-V-Q-D-V-D-R-G-E-N-I-L-V-I-R-T-A-D-G-H-A-S-G-V-A-L-L-L-D-R-W-K-R-D-D-I-V-G-T-L-A-G-E-D-T-I-M-V-V-A-R-S-T-H-D-G-E-S-L-M-E-E-F-N-A-L-M-L-G"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-L-D-K-L-L-E-N-E-A-Q-S-E-I-E-R-I-R-A-E-A-R-G-R-A-E-K-I-V-A-D-A-R-E-R-A-Q-T-L-L-D-S-R-Q-R-L-L-E-N-Q-R-Q-A-G-L-V-R-A-R-S-A-A-D-L-E-L-N-A-A-R-L-T-A-S-E-S-G-V-T-Q-V-Y-Q-M-V-E-D-Y-L-G-N-V-T-S-A-P-E-Y-G-N-I-L-S-R-L-I-Q-E-G-L-Q-A-V-P-D-A-E-A-I-E-V-N-P-A-E-M-N-V-A-R-H-L-V-S-G-V-E-V-R-E-N-P-S-I-K-G-G-V-R-V-V-A-R-G-G-K-S-G-V-T-N-T-L-S-G-R-L-E-R-V-K-A-D-M-A-P-Q-I-S-R-L-L-A-E"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-R-L-H-L-I-T-V-G-E-P-K-L-A-Y-A-R-S-G-W-D-E-Y-E-K-R-L-R-R-Y-H-K-V-Q-V-S-R-V-S-G-K-T-Q-Q-A-E-S-E-A-I-L-K-A-A-G-K-S-P-L-I-L-L-D-P-R-G-K-Q-F-S-S-E-K-L-S-E-Y-L-D-A-E-A-L-G-G-H-G-E-L-A-F-A-I-G-G-P-D-G-H-T-D-A-L-R-G-Q-A-K-L-L-W-S-L-G-E-L-T-L-P-H-D-L-A-M-L-V-L-V-E-A-L-Y-R-A-A-T-I-S-A-G-E-P-Y-H-R-G"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-T-R-P-T-I-P-P-G-P-P-G-A-E-G-R-T-Q-T-L-E-R-T-E-T-K-K-P-R-L-W-R-V-L-L-L-N-D-D-Y-T-P-M-D-Y-V-V-Q-V-L-E-Q-F-F-R-K-T-E-Q-E-A-E-L-I-M-L-A-V-H-H-K-G-Q-G-V-A-G-V-Y-T-R-D-V-A-E-T-K-V-A-Q-V-T-A-H-A-Q-R-E-G-H-P-L-R-V-V-A-E-P-E-S-E-G-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-I-D-K-Q-Q-V-I-S-D-N-A-A-G-A-N-D-T-G-S-T-A-V-Q-V-A-L-L-T-A-R-I-N-N-L-A-G-H-L-Q-T-N-K-K-D-K-A-G-Q-R-G-L-Q-L-M-N-G-Q-R-R-R-L-L-K-Y-L-E-R-T-D-Y-D-A-Y-I-A-L-T-D-K-L-G-I-R-R-G-Q-R-I-V-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-K-K-T-F-T-G-V-V-V-S-D-K-A-D-K-T-V-S-V-K-V-E-R-R-F-A-H-P-L-Y-G-K-V-V-T-R-S-H-K-Y-A-A-H-D-E-N-N-E-Y-K-I-G-D-R-V-E-I-I-A-V-R-P-I-S-K-T-K-T-W-K-V-T-K-L-I-E-R-P-R-G-I-E-T-T-L-A-E-T-E-V-A-G-G-E-A"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-V-E-D-H-L-L-K-K-V-D-A-Q-N-D-K-K-D-K-R-V-I-K-T-W-S-R-R-S-T-I-V-P-E-M-I-G-H-T-I-A-V-Y-N-G-K-Q-H-V-P-V-F-V-N-E-Q-M-I-G-H-K-L-G-E-F-S-P-T-R-T-Y-R-G-H-G-A-D-K-N-A-K-G-S-K-K-K"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-V-A-P-K-I-R-I-K-L-R-G-F-D-H-K-A-L-D-Q-S-A-S-K-I-V-D-T-V-R-R-T-G-A-D-V-S-G-P-V-P-L-P-T-R-I-R-R-F-T-V-L-R-S-P-F-K-Y-K-D-S-R-E-H-F-E-I-R-T-H-N-R-L-V-D-I-M-N-P-T-K-K-T-I-D-S-L-M-T-L-D-L-P-T-G-V-D-I-E-I-K-T-V-G-G-R-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-A-R-R-R-R-A-E-V-R-P-V-Q-P-D-L-V-Y-Q-D-V-L-V-S-A-M-I-N-R-I-M-R-D-G-K-K-N-L-A-S-R-I-F-Y-G-A-C-R-L-V-Q-E-R-T-G-Q-E-P-L-K-V-F-K-Q-A-Y-D-N-V-K-P-R-V-E-V-R-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-G-P-R-R-Q-Q-S-L-T-L-R-W-M-I-S-A-V-D-G-R-P-E-R-T-A-I-E-R-L-A-G-E-I-M-D-A-A-Q-G-R-G-G-A-I-K-K-K-D-D-V-E-R-M-A-E-A-N-R-A-Y-A-H-Y-R-W"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-V-A-V-G-H-D-L-I-E-I-A-R-I-R-R-M-L-E-R-E-G-V-R-A-E-R-L-F-T-A-T-E-L-A-Y-A-G-R-Y-R-D-P-A-P-S-L-A-A-R-F-A-A-K-E-A-F-Q-K-V-W-L-R-P-H-G-W-R-D-V-W-V-E-R-E-R-T-P-D-G-P-F-P-Y-A-A-P-M-L-G-F-A-P-A-I-A-G-E-M-H-E-R-G-W-V-A-H-L-T-L-T-H-T-R-E-H-A-S-A-V-V-I-L-E-H-L-E-Q-R-A-A-P"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-S-F-P-L-W-L-W-L-A-L-G-G-A-V-G-A-V-C-R-Q-A-A-V-L-L-L-A-P-L-V-A-R-T-G-F-P-A-A-V-L-L-I-N-V-L-G-S-F-L-L-G-L-T-L-A-L-T-G-R-G-V-W-P-E-A-V-R-M-T-F-G-T-G-V-L-G-A-F-T-T-F-S-T-F-S-T-E-L-D-G-L-L-L-R-G-Q-G-G-L-A-L-A-Y-A-A-L-S-V-G-L-G-L-T-A-A-V-A-G-R-V-L-G-A-R-L"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-Q-R-I-E-A-T-L-L-A-H-D-L-K-F-A-L-V-S-T-R-W-N-H-L-I-V-D-R-L-V-E-G-A-E-L-A-F-V-Q-H-G-G-K-T-E-N-L-D-H-F-L-V-P-G-S-Y-E-V-P-L-V-A-R-R-L-A-E-T-G-R-Y-D-A-V-V-C-L-G-A-V-I-K-G-D-T-D-H-Y-D-F-V-A-G-G-A-A-N-G-I-L-N-T-S-L-H-T-G-V-P-V-A-F-G-V-L-T-T-D-T-V-E-Q-A-L-N-R-A-G-I-K-A-G-N-K-G-G-E-A-V-L-A-M-I-E-T-A-N-L-L-K-Q-I-E-R"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-V-T-E-L-R-N-G-T-K-V-Q-M-D-G-G-L-W-E-C-L-D-Y-S-H-L-K-M-G-R-G-G-A-K-V-V-T-K-F-R-N-M-E-S-G-S-I-V-D-R-T-F-N-S-T-E-K-L-Q-D-I-Y-V-E-G-K-K-M-Q-Y-L-Y-P-D-G-D-D-Y-V-F-M-D-M-E-T-F-D-Q-V-H-L-G-K-N-I-V-S-D-A-A-K-F-M-K-E-N-T-E-V-E-V-A-M-Y-G-D-K-A-L-S-I-S-L-P-N-Q-V-I-L-K-I-T-Q-T-D-P-G-V-R-G-D-T-V-S-G-G-T-K-P-A-T-L-E-T-G-A-V-V-Q-V-P-L-F-V-E-Q-G-T-D-V-K-V-D-T-R-T-G-Q-Y-L-S-R-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-T-Q-Q-G-N-S-G-E-R-K-P-R-G-K-G-P-K-R-P-R-K-P-K-V-D-P-F-S-I-G-E-L-E-I-T-D-Y-K-D-V-K-M-L-R-R-F-V-S-D-T-G-K-I-L-P-R-R-R-T-G-L-S-A-K-H-Q-R-R-I-A-Q-T-I-K-V-A-R-Q-L-A-L-L-P-Y-T-E-K-L-V-R-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-N-Q-Y-D-L-N-L-I-L-N-P-N-I-S-A-E-Q-V-Q-T-E-K-D-Y-I-E-N-A-V-R-N-A-G-A-E-I-S-N-L-D-D-L-G-N-R-R-L-A-Y-Q-V-G-K-D-R-E-G-Y-Y-L-M-Y-T-I-K-A-S-G-N-P-E-T-A-I-A-S-S-L-R-L-R-D-N-V-R-R-V-L-V-V-K-D-R-P-E-W-K-T-K-K-A"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-Y-C-S-S-P-D-S-R-V-I-N-S-R-P-S-D-D-G-A-S-I-R-R-R-R-E-C-L-T-C-T-R-R-F-T-T-Y-E-R-A-Q-L-E-P-L-M-V-V-K-R-S-G-V-R-E-A-F-N-P-D-K-L-L-R-G-L-A-L-A-S-E-K-R-P-V-E-E-A-A-L-R-T-F-A-Y-S-F-E-D-E-V-Q-G-G-E-I-P-T-E-E-I-G-R-R-A-M-T-F-L-R-P-L-D-D-V-A-Y-I-R-F-A-S-V-Y-R-D-F-D-S-L-E-R-F-I-E-E-I-R-G-L-K-G-H-E-D-E-A-P-K-S-D-P-A"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-A-S-I-A-L-A-L-I-D-V-A-G-D-V-L-R-E-H-G-A-A-R-A-S-A-L-T-V-R-V-G-Q-W-S-S-V-V-P-E-A-L-A-A-A-F-P-A-C-A-E-G-T-P-L-A-G-A-R-L-S-I-E-R-V-P-G-V-G-E-C-P-Q-H-G-P-V-E-L-E-V-W-R-G-L-R-C-P-L-C-G-A-P-T-P-R-L-L-Q-G-D-E-L-E-L-D-Q-L-E-L-D-Q-L-E-L-E-N-L"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-T-R-L-T-G-L-R-R-P-L-L-P-I-A-G-A-K-Q-A-P-E-Q-A-I-D-G-P-Q-V-E-V-P-L-T-A-V-D-R-R-R-V-R-R-R-L-H-A-P-D-G-A-E-L-Q-L-A-F-P-T-G-T-V-L-S-P-G-T-V-L-G-T-R-G-G-V-S-Y-V-V-S-A-A-P-E-D-V-A-V-V-V-P-R-T-L-A-E-A-A-H-T-A-H-A-V-G-N-L-H-R-D-F-V-E-D-A-G-A-F-L-T-P-W-D-A-P-I-E-L-L-L-T-R-L-G-V-P-F-T-R-E-T-R-P-F-H-G-R-P-S-W-E-H-E-G"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-T-K-K-S-T-K-A-P-A-K-K-A-A-P-A-A-K-A-A-P-A-A-K-R-G-A-A-A-D-S-G-K-V-A-K-T-Q-L-V-E-M-V-A-D-Q-T-G-L-T-K-K-Q-S-E-E-A-I-S-S-M-L-E-C-V-V-S-A-L-Q-S-G-K-S-V-G-L-P-G-L-G-T-L-S-V-K-E-T-A-A-R-T-G-V-R-P-G-T-S-E-K-I-Q-I-P-A-G-K-K-V-A-F-K-V-A-S-T-L-K-G-N-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-L-R-L-V-Y-D-S-L-T-G-N-V-R-H-F-A-E-T-L-A-A-E-L-H-V-S-P-M-R-V-Q-D-P-A-P-T-D-A-Y-L-L-L-T-Y-T-F-G-S-G-E-V-P-A-S-T-R-R-L-L-T-T-H-G-H-L-L-R-G-V-V-A-S-G-S-Y-H-W-G-H-N-F-A-R-A-A-D-V-I-A-A-E-Y-R-V-P-V-V-A-K-L-N-K-G-G-T-A-A-D-R-A-A-V-R-R-W-L-L-H-Y-A-E-S-A-P-P-F-P-T-S-C-T-G-E-P-T-P-W-N-A-G"} +{"text": "### FUNCTION An outer membrane protein that may participate in pathogenesis Some human Lyme disease patients have antibodies against this protein ### SEQUENCE -M-K-I-I-N-I-L-F-C-L-F-L-L-M-L-N-S-C-N-S-N-D-T-N-T-S-Q-T-K-S-R-Q-K-R-D-L-T-Q-K-E-A-T-Q-E-K-P-K-S-K-E-D-L-L-R-E-K-L-S-E-D-Q-K-T-H-L-D-W-L-K-T-A-L-T-G-A-G-E-F-D-K-F-L-G-Y-D-E-D-K-I-K-G-A-L-N-H-I-K-S-E-L-D-K-C-T-G-D-N-S-E-Q-Q-K-S-T-F-K-E-V-V-K-G-A-L-G-G-G-I-D-S-F-A-T-S-A-S-S-T-C-Q-A-Q-Q"} +{"text": "### FUNCTION An outer membrane protein that may participate in pathogenesis Some human Lyme disease patients have antibodies against this protein ### SEQUENCE -M-K-I-I-N-I-L-F-C-L-F-L-L-M-L-N-G-C-N-S-N-D-N-D-T-L-K-N-N-A-Q-Q-T-K-S-R-R-K-R-D-L-T-Q-K-E-V-T-Q-E-K-P-K-S-K-E-E-L-L-R-E-K-L-N-D-D-Q-K-T-Q-L-D-W-L-K-T-A-L-T-D-A-G-E-F-D-K-F-L-E-N-N-E-D-K-I-K-S-A-L-D-H-I-K-S-E-L-D-K-C-N-G-K-E-N-G-D-V-Q-K-N-T-F-K-Q-V-V-Q-G-A-L-K-G-G-I-D-G-F-G-A-S-N-A-T-T-T-C-N-G-S"} +{"text": "### FUNCTION An outer membrane protein that may participate in pathogenesis Some human Lyme disease patients have antibodies against this protein ### SEQUENCE -M-K-I-I-N-I-L-F-C-L-F-L-L-M-L-N-G-C-N-S-N-D-T-N-T-K-Q-T-K-S-R-Q-K-R-D-L-T-Q-K-E-A-T-Q-E-K-P-K-S-K-S-K-E-D-L-L-R-E-K-L-S-D-D-Q-K-T-Q-L-D-W-L-K-T-A-L-T-G-V-G-K-F-D-K-F-L-E-N-D-E-G-K-I-K-S-A-L-E-H-I-K-T-E-L-D-K-C-N-G-N-D-E-G-K-N-T-F-K-T-T-V-Q-G-F-F-S-G-G-N-I-D-N-F-A-D-Q-A-T-A-T-C-N"} +{"text": "### FUNCTION An outer membrane protein that may participate in pathogenesis Some human Lyme disease patients have antibodies against this protein ### SEQUENCE -M-K-I-I-N-I-L-F-C-L-F-L-L-L-L-N-S-C-N-S-N-D-N-D-T-L-K-N-N-A-Q-Q-T-K-S-R-G-K-R-D-L-T-Q-K-E-A-T-P-E-K-P-K-S-K-E-E-L-L-R-E-K-L-S-E-D-Q-K-T-H-L-D-W-L-K-E-A-L-G-N-D-G-E-F-D-K-F-L-G-Y-D-E-S-K-I-K-S-A-L-N-H-I-K-S-E-L-D-K-C-T-G-D-N-S-E-Q-Q-K-S-T-F-K-Q-T-V-Q-G-F-F-S-G-G-N-I-D-N-F-A-N-N-A-V-S-N-C-N-N-G-G-S"} +{"text": "### FUNCTION An outer membrane protein that may participate in pathogenesis Some human Lyme disease patients have antibodies against this protein ### SEQUENCE -M-K-I-I-N-I-L-F-C-L-F-L-L-M-L-N-G-C-N-S-N-D-T-N-N-S-Q-T-K-S-R-Q-K-R-D-L-T-Q-K-E-A-T-Q-E-K-P-K-S-K-E-E-L-L-R-E-K-L-N-D-N-Q-K-T-H-L-D-W-L-K-E-A-L-G-N-D-G-E-F-N-K-F-L-G-Y-D-E-S-K-I-K-S-A-L-D-H-I-K-S-E-L-D-S-C-T-G-D-K-V-E-N-K-N-T-F-K-Q-V-V-Q-E-A-L-K-G-G-I-D-G-F-E-N-T-A-S-S-T-C-K-N-S"} +{"text": "### FUNCTION An outer membrane protein that may participate in pathogenesis Some human Lyme disease patients have antibodies against this protein ### SEQUENCE -M-K-I-I-N-I-L-F-C-L-F-L-L-M-L-N-G-C-N-S-N-D-N-D-T-L-K-N-N-A-Q-Q-T-K-R-R-G-K-R-D-L-T-Q-K-E-T-T-Q-E-K-P-K-S-K-E-E-L-L-R-E-K-L-S-D-D-Q-K-T-H-L-D-W-L-K-P-A-L-T-G-A-G-E-F-D-K-F-L-E-N-D-D-D-K-I-K-S-A-L-D-H-I-K-T-Q-L-D-S-C-N-G-D-Q-A-E-Q-Q-K-T-T-F-K-T-V-V-T-E-F-F-K-N-G-D-I-D-N-F-A-T-G-A-V-S-N-C-N-N-G-G"} +{"text": "### FUNCTION Component of the phosphoenolpyruvate-dependent nitrogen-metabolic phosphotransferase system proteins ### SEQUENCE -M-T-K-L-E-R-Q-V-T-I-C-N-K-L-G-L-H-A-R-A-A-T-K-L-A-I-L-A-S-E-F-D-A-E-I-T-I-V-Q-G-E-K-K-A-S-A-A-S-V-L-G-L-L-M-L-E-T-G-M-G-K-T-I-T-L-L-G-K-G-Q-D-A-D-A-A-L-D-A-I-C-A-L-V-D-A-K-F-D-E-A-S"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-S-P-S-R-S-P-R-K-R-V-R-K-Q-V-A-D-G-M-A-H-I-H-A-S-F-N-N-T-I-I-T-I-T-D-R-Q-G-N-A-L-S-W-A-T-S-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-R-A-G-V-A-A-Q-D-Y-G-V-K-N-L-E-V-F-V-K-G-P-G-P-G-R-E-S-A-I-R-A-L-N-S-V-G-Y-K-I-T-N-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-T-V-I-A-L-T-G-I-F-G-I-G-R-T-R-A-R-A-I-C-A-A-T-S-I-A-E-D-A-K-I-K-E-L-S-E-A-Q-I-D-I-L-R-E-A-V-A-E-Y-T-V-E-G-D-L-R-R-E-V-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-I-R-H-R-R-S-L-P-L-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-R-K"} +{"text": "### FUNCTION May function as a system-specific chaperone protein essential for the assembly of an active selenate reductase SerABC ### SEQUENCE -M-N-A-L-I-D-N-P-E-A-L-A-S-G-Y-L-A-M-A-Q-V-F-S-Y-P-D-A-G-A-W-S-R-L-T-E-R-G-L-V-D-P-A-L-T-H-E-T-L-E-A-E-Y-L-A-A-F-E-M-G-G-G-K-A-T-V-S-L-Y-E-G-Q-N-R-P-D-L-G-R-D-G-I-L-Q-E-L-L-R-F-Y-E-F-F-D-A-Q-L-S-E-D-D-R-E-Y-P-D-H-L-V-T-E-L-E-F-L-A-W-L-C-L-Q-E-H-A-A-V-R-D-G-R-D-A-E-P-F-R-R-A-A-R-D-F-L-D-R-H-L-A-A-W-L-P-E-F-R-R-R-L-E-A-T-D-S-A-Y-A-Q-Y-G-P-A-L-G-E-L-V-E-A-H-R-S-R-L-G-E-Q-A-P-Q-L-G-E-L-Q"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-E-I-E-K-T-E-S-A-E-E-V-F-A-V-P-E-P-D-V-P-W-V-T-I-V-H-N-D-P-V-N-L-M-S-Y-V-T-Y-V-F-Q-S-Y-F-G-Y-S-K-D-K-A-T-K-L-M-M-D-V-H-H-K-G-R-A-V-V-S-S-G-S-R-E-E-M-E-R-D-V-Q-A-M-H-G-Y-G-L-W-A-T-L-Q-Q-D-R-K"} +{"text": "### FUNCTION Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm ### SEQUENCE -M-K-K-L-L-C-A-A-S-F-G-I-A-L-A-F-S-A-G-A-Q-A-A-D-K-I-A-V-V-N-V-G-E-I-F-Q-Q-L-P-A-R-E-A-V-A-K-Q-L-E-N-E-F-K-N-R-A-S-E-L-Q-R-M-E-T-D-L-Q-S-K-I-Q-K-L-Q-R-D-G-S-T-M-K-S-S-E-R-T-N-L-E-K-E-V-M-A-K-R-E-E-F-G-K-K-A-Q-A-F-E-Q-D-H-R-R-R-E-M-E-E-R-N-K-I-L-S-R-I-Q-D-A-I-K-V-V-A-G-K-E-G-Y-D-I-V-I-D-A-N-A-V-A-Y-S-V-S-G-K-N-I-T-A-S-V-L-K-Q-V-K"} +{"text": "### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-A-F-R-E-N-V-L-E-I-L-E-E-I-T-E-T-D-E-V-V-Q-N-T-N-I-K-L-F-D-E-G-L-L-D-S-M-A-T-V-Q-L-L-I-E-I-E-E-K-L-D-I-T-V-P-V-S-E-F-D-R-D-E-W-A-T-P-E-M-I-I-T-Q-L-E-A-L-K"} +{"text": "### FUNCTION Involved in SOS regulation Inhibits RecA by preventing RecA to bind ssDNA Can displace ssDNA from RecA Inhibits NucA transcription ### SEQUENCE -M-R-V-E-V-T-I-D-K-T-R-P-L-P-A-G-A-I-E-A-L-T-G-E-L-G-K-R-V-N-R-Q-F-P-D-A-V-V-H-V-R-Y-A-G-A-N-G-L-S-V-L-G-G-A-K-T-D-R-D-L-I-E-E-I-L-Q-E-T-W-E-S-A-D-E-W-F-S-A-E"} +{"text": "### FUNCTION Transcription regulator that can specifically activate or repress expression of target genes Required for expression of the virulence gene inv Important for the regulation of genes that influence the early stages of infection that occur in the Peyer plaque ### SEQUENCE -M-E-S-T-L-G-S-D-L-A-R-L-V-R-V-W-R-A-L-I-D-H-R-L-K-P-L-E-L-T-Q-T-H-W-V-T-L-H-N-I-N-R-L-P-P-E-Q-S-Q-I-Q-L-A-K-A-I-G-I-E-Q-P-S-L-V-R-T-L-D-Q-L-E-E-K-G-L-I-T-R-H-T-C-A-N-D-R-R-A-K-R-I-K-L-T-E-Q-S-S-P-I-I-E-Q-V-D-G-V-I-C-S-T-R-K-E-I-L-G-G-I-S-P-D-E-I-E-L-L-S-G-L-I-D-K-L-E-R-N-I-I-Q-L-Q-S-K"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-S-V-A-Y-I-L-I-F-T-L-T-I-G-T-L-F-F-A-V-A-F-R-E-P-P-R-I-E-R-K-E-K"} +{"text": "### FUNCTION Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control PhzB2 has a role in the biosynthesis of the phenazine during both planktonic growth and biofilm development, and in host infection during biofilm development ### SEQUENCE -M-L-D-N-A-I-P-Q-G-F-E-D-A-V-E-L-R-R-K-N-R-E-T-V-V-K-Y-M-N-T-K-G-Q-D-R-L-R-R-H-E-L-F-V-E-D-G-C-G-G-L-W-T-T-D-T-G-S-P-I-V-I-R-G-K-D-K-L-A-E-H-A-V-W-S-L-K-C-F-P-D-W-E-W-Y-N-I-K-V-F-E-T-D-D-P-N-H-F-W-V-E-C-D-G-H-G-K-I-L-F-P-G-Y-P-E-G-Y-Y-E-N-H-F-L-H-S-F-E-L-D-D-G-K-I-K-R-N-R-E-F-M-N-V-F-Q-Q-L-R-A-L-S-I-P-V-P-Q-I-K-R-E-G-I-P-T"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-E-K-S-L-H-L-E-I-V-T-P-D-R-L-V-L-S-E-K-V-D-Y-V-G-A-P-G-Y-E-G-E-F-G-I-L-P-N-H-I-P-F-L-S-A-L-N-I-G-S-L-Y-Y-K-A-G-G-K-T-H-W-I-F-V-S-G-G-F-A-E-V-S-D-N-K-V-T-V-L-A-E-S-A-E-R-A-E-D-I-D-L-E-R-A-R-K-A-K-E-R-A-E-Q-R-L-A-Q-A-K-E-K-L-D-S-A-R-A-Q-A-A-L-Q-R-A-M-A-R-M-R-V-R-G-A-A"} +{"text": "### FUNCTION May form complexes with phosphorylated ligands by interfering with kinases and their effectors ### SEQUENCE -M-S-L-S-R-R-D-P-L-V-V-G-S-V-V-G-D-V-L-D-P-F-T-R-L-V-S-L-K-V-T-Y-G-H-R-E-V-T-N-G-L-D-L-R-P-S-Q-V-L-N-K-P-I-V-E-I-G-G-D-D-F-R-N-F-Y-T-L-V-M-V-D-P-D-V-P-S-P-S-N-P-H-Q-R-E-Y-L-H-W-L-V-T-D-I-P-A-T-T-G-N-A-F-G-N-E-V-V-C-Y-E-S-P-R-P-P-S-G-I-H-R-I-V-L-V-L-F-R-Q-L-G-R-Q-T-V-Y-A-P-G-W-R-Q-Q-F-N-T-R-E-F-A-E-I-Y-N-L-G-L-P-V-A-A-S-Y-F-N-C-Q-R-E-N-G-C-G-G-R-R-T"} +{"text": "### FUNCTION Essential component of the TIM1723 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane Links the inner and outer membranes ### SEQUENCE -M-A-D-P-M-N-H-S-T-G-H-Q-Q-Q-Q-K-Y-R-Q-Y-N-P-Y-Q-Q-V-N-L-P-Y-R-K-L-Y-E-L-P-T-S-P-E-F-L-F-E-E-E-A-T-K-K-R-L-T-W-G-E-N-L-T-F-F-T-G-W-G-Y-C-T-G-S-V-L-G-A-F-K-G-T-I-A-G-M-R-A-A-E-R-G-E-S-L-K-I-R-T-N-R-I-L-N-S-G-G-L-V-A-R-R-G-G-N-C-L-G-S-V-G-L-M-F-A-A-M-E-S-G-V-T-Y-M-R-D-G-D-D-G-S-L-T-T-V-I-A-G-L-A-T-G-V-L-Y-R-A-A-S-G-P-R-S-A-V-V-A-G-A-V-G-G-V-A-A-L-A-A-V-A-G-R-R-I-V-K-R-F-V-P-I"} +{"text": "### FUNCTION D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc ### SEQUENCE -N-E-Q-S-G-I-S-Q-T-V-I-V-G-P-W-G-A-Q-V-T"} +{"text": "### FUNCTION D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc ### SEQUENCE -K-Q-R-S-G-E-S-Q-N-I-I-V-G-S-W-G-A-K-V-S"} +{"text": "### FUNCTION May only reduce GSH-thiol disulfides, but not protein disulfides ### SEQUENCE -M-E-K-I-S-N-L-L-E-D-K-P-V-V-I-F-S-K-T-S-C-C-M-S-H-S-I-K-S-L-I-S-G-Y-G-A-N-S-T-V-Y-E-L-D-E-M-S-N-G-P-E-I-E-R-A-L-V-E-L-G-C-K-P-T-V-P-A-V-F-I-G-Q-E-L-V-G-G-A-N-Q-L-M-S-L-Q-V-R-N-Q-L-A-S-L-L-R-R-A-G-A-I-W-I"} +{"text": "### FUNCTION Probable cyclin-dependent protein kinase inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle ### SEQUENCE -M-G-Y-S-G-K-P-H-H-Q-L-D-G-E-I-R-E-S-T-D-G-K-K-W-V-I-A-G-I-P-S-R-S-P-L-K-Q-I-N-L-S-P-G-V-T-V-T-E-T-E-E-Q-D-Q-C-P-T-T-P-T-A-V-S-V-R-I-P-R-V-P-P-C-P-A-A-P-K-K-R-K-P-S-L-K-C-S-Y-V-T-V-T-R-D-Y-F-S-P-P-D-L-E-T-V-F-I-Q-R-A-S-Y"} +{"text": "### FUNCTION Provides oxygen to the bacteroids This role is essential for symbiotic nitrogen fixation ### SEQUENCE -M-G-F-T-E-K-Q-E-A-L-V-N-S-S-W-E-L-F-K-Q-N-P-S-Y-S-V-L-F-Y-T-I-I-L-K-K-A-P-A-A-K-G-M-F-S-F-L-K-D-S-A-E-V-V-D-S-P-K-L-Q-A-H-A-E-K-V-F-G-M-V-H-D-S-A-I-Q-L-R-A-S-G-E-V-V-L-G-D-A-T-L-G-A-I-H-I-Q-K-G-V-V-D-P-H-F-V-V-V-K-E-A-L-L-E-T-I-K-E-A-S-G-E-K-W-S-E-E-L-S-T-A-W-E-V-A-Y-E-G-L-A-S-A-I-K-K-A-M-N"} +{"text": "### FUNCTION Provides oxygen to the bacteroids This role is essential for symbiotic nitrogen fixation ### SEQUENCE -M-G-F-T-E-K-Q-E-A-L-V-N-S-S-W-E-L-F-K-Q-N-P-S-Y-S-V-L-F-Y-T-I-I-L-K-K-A-P-A-A-K-G-M-F-S-F-L-K-D-S-A-E-V-V-D-S-P-K-L-Q-A-H-A-E-K-V-F-G-M-V-H-D-S-A-I-Q-L-R-A-S-G-E-V-V-L-G-D-V-T-L-G-A-I-H-I-Q-K-G-V-I-D-P-H-F-V-V-V-K-E-A-L-L-D-T-I-K-E-A-S-G-E-K-W-S-E-E-L-S-T-A-W-E-I-A-Y-E-G-L-A-S-A-I-K-K-A-M-N"} +{"text": "### FUNCTION Thionins are small plant proteins which are toxic to animal cells They seem to exert their toxic effect at the level of the cell membrane Their precise function is not known ### SEQUENCE -M-E-G-K-T-V-I-L-G-V-I-I-M-S-L-V-M-A-Q-N-Q-V-E-A-K-I-C-C-P-R-T-I-D-R-N-I-Y-N-A-C-R-L-T-G-A-S-M-T-N-C-A-N-L-S-G-C-K-I-V-S-G-T-T-C-P-P-G-Y-T-H-D-I-L-Q-N-Y-G-D-A-V-N-E-Y-C-K-L-G-C-A-S-S-V-C-G-A-L-T-T-L-K-N-S-M-Q-V-N-C-E-G-A-V-S-Q-C-T-N-A-C-S-N-F-C-T-K-G-S-A-K-V-V-E-T-A"} +{"text": "### FUNCTION May function in mediating the binding of the antenna complexes to the PSI reaction center and core antenna ### SEQUENCE -M-A-V-A-M-R-A-Q-C-A-K-V-Q-A-A-R-P-A-R-A-T-T-V-V-C-R-A-S-A-Q-S-R-R-E-L-L-G-L-G-V-L-L-G-A-A-A-L-A-P-A-A-N-A-G-V-V-E-D-L-L-A-K-S-A-A-N-K-A-L-N-N-K-K-R-L-A-T-S-Y-A-N-L-A-R-S-R-T-V-Y-D-G-T-C-Q-F-P-E-N-F-F-G-C-E-E-L-A-F-N-K-G-V-K-Y-I-A-E-D-L-K-I-E-C-E-G-K-D-A-K-S-C-G-S-K-F-T-L-R-S-K"} +{"text": "### FUNCTION Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts ### SEQUENCE -M-S-D-E-E-H-Q-F-E-S-K-A-D-A-G-A-S-K-T-Y-P-Q-Q-A-G-T-I-R-K-G-G-H-I-V-I-K-N-R-A-C-K-V-V-E-V-S-T-S-K-T-G-K-H-G-H-A-K-C-H-F-V-A-I-D-I-F-N-G-K-K-L-E-D-I-V-P-S-S-H-N-C-D-V-P-H-V-N-R-T-D-Y-Q-L-I-D-I-S-E-D-G-F-V-S-L-L-T-E-N-G-N-T-K-D-D-L-K-L-P-T-D-D-A-L-L-T-Q-I-K-D-G-F-G-E-G-K-D-L-V-V-S-V-M-S-A-M-G-E-E-Q-I-C-A-L-K-D-I-G-P-K"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-A-F-T-P-K-I-I-T-C-L-I-V-L-T-I-Y-M-A-S-P-T-E-S-T-I-Q-C-G-T-V-T-S-T-L-A-Q-C-L-T-Y-L-T-N-S-G-P-L-P-S-Q-C-C-V-G-V-K-S-L-Y-Q-L-A-Q-T-T-P-D-R-K-Q-V-C-E-C-L-K-L-A-G-K-E-I-K-G-L-N-T-D-L-V-A-A-L-P-T-T-C-G-V-S-I-P-Y-P-I-S-F-S-T-N-C-D-S-I-S-T-A-V"} +{"text": "### FUNCTION Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate as sulfonate donor ### SEQUENCE -M-F-F-A-L-C-V-A-L-S-G-R-E-V-N-K-T-R-R-T-V-N-G-V-D-H-K-D-F-F-R-D-G-K-V-G-D-W-K-N-H-L-S-V-T-L-E-T-E-N-K-I-D-M-T-I-K-E-K-F-Q-G-S-G-T-Q-D"} +{"text": "### FUNCTION Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner ### SEQUENCE -M-V-A-A-I-I-A-G-A-A-V-A-A-A-A-Y-A-G-K-Y-G-I-E-A-W-Q-A-F-K-L-R-P-V-R-P-R-M-R-K-F-Y-E-G-G-F-Q-A-T-M-N-R-R-E-A-A-L-I-L-G-V-R-E-S-V-A-A-E-K-V-K-E-A-H-R-R-V-M-V-A-N-H-P-D-A-G-G-S-H-Y-L-A-S-K-I-N-E-A-K-D-M-M-L-G-K-T-K-N-S-G-S-A-F"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-F-D-D-Q-D-L-G-F-F-A-N-F-L-G-I-F-I-F-I-L-V-I-A-Y-H-F-V-M-A-D-P-K-F-E"} +{"text": "### FUNCTION Heavy-metal-binding protein ### SEQUENCE -M-T-V-K-K-V-E-I-K-V-D-I-N-C-G-K-C-N-S-A-I-M-E-A-V-T-E-I-E-G-V-N-H-I-S-L-D-E-G-N-S-I-L-T-V-V-G-T-M-D-P-V-C-V-A-T-R-L-K-K-I-K-Q-K-P-V-I-I-S-V-G-P-P-P-K-P-P-E-P-P-K-P-P-E-P-E-K-P-K-P-P-P-A-P-E-P-P-K-H-V-C-K-P-P-Y-C-N-S-C-D-V-V-S-V-T-T-Y-E-S-G-S-G-C-T-I-L"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-K-S-E-N-V-N-K-R-D-E-Y-Q-R-V-F-S-C-F-D-K-S-H-Q-G-K-V-S-V-S-T-I-E-R-C-V-D-A-I-K-S-G-K-R-A-V-V-D-Q-E-D-T-T-N-P-N-P-E-E-S-T-D-D-K-S-L-E-L-E-D-F-V-K-L-V-E-E-G-E-E-A-D-K-E-K-D-L-K-E-A-F-K-L-Y-E-E-S-E-G-I-T-P-K-S-L-K-R-M-L-S-L-L-G-E-S-K-S-L-K-D-C-E-V-M-I-S-Q-F-D-I-N-R-D-G-I-I-N-F-D-E-F-R-A-M-M-Q"} +{"text": "### FUNCTION Plays a role in the regulation of cell expansion, root meristem patterning and auxin transport ### SEQUENCE -M-K-Q-L-I-R-R-L-S-R-V-A-D-S-T-Q-Y-S-L-L-R-S-E-S-Q-R-G-R-T-K-K-E-K-H-K-S-W-V-P-E-G-H-V-P-V-Y-V-G-H-E-M-E-R-F-V-V-N-A-E-L-L-N-H-P-V-F-V-A-L-L-K-Q-S-A-Q-E-Y-G-Y-E-Q-Q-G-V-L-R-I-P-C-H-V-L-V-F-E-R-I-L-E-S-L-R-L-G-L-A-D-R-V-T"} +{"text": "### FUNCTION Catalyzes the conversion of methylthioalkyl glucosinolates of any chain length into methylsulfinylalkyl glucosinolates ### SEQUENCE -M-A-P-S-L-S-P-I-R-S-H-H-V-A-V-I-G-A-G-A-A-G-L-V-A-A-R-E-L-R-R-E-G-H-S-V-V-V-F-E-R-Q-K-Q-V-G-G-T-W-I-Y-T-D-H-I-E-P-D-P-L-S-V-D-P-T-R-S-V-V-H-S-S-V-Y-G-S-L-R-T-N-L-P-R-E-C-M-G-Y-R-D-F-P-F-V-V-R-S-G-V-S-E-S-R-D-P-R-R-F-P-S-H-G-E-V-L-A-Y-L-Q-D-F-A-K-E-F-A-I-E-E-M-I-R-F-D-T-A-V-V-K-V-A-P-A-A-E-E-G-S-G-K-W-R-I-E-S-T-E-K-E-K-K-K-W-A-H-R-A-V"} +{"text": "### FUNCTION Provide a mechanistic link between auxin and plasma membrane H ### SEQUENCE -M-S-I-L-K-K-S-T-K-L-A-Q-T-A-M-L-R-Q-I-L-K-R-C-S-S-L-G-K-K-N-G-G-G-G-Y-E-E-V-D-L-P-L-D-V-P-K-G-H-F-P-V-Y-V-G-H-N-R-S-R-Y-I-V-P-I-S-F-L-T-N-L-D-F-Q-C-L-L-R-R-A-E-E-E-F-G-F-D-H-D-M-G-L-T-I-P-C-D-E-L-F-F-Q-D-L-T-S-M-I-R"} +{"text": "### FUNCTION Probable inactive paralog of AtUNG generated by a gene duplication event and subsequently disrupted by at least two transposon insertions ### SEQUENCE -M-A-L-S-T-P-K-T-L-M-D-F-F-Q-P-A-K-R-L-K-A-S-P-S-S-S-S-S-F-P-A-V-S-V-A-G-R-S-R-D-L-G-S-V-A-N-S-P-P-R-V-T-V-T-T-A-V-A-D-D-S-S-G-L-T-P-E-Q-V-A-R-A-E-F-H-K-F-V-A-K-S-K-S-N-L-A-V-C-S-V-K-V-T-K-A-K-G-L-I-L-I-M-D-L-V-K-L-W-V-Y-P-S-M-C-L-K-E-K-S-P-S-S-L-L-N-I-F-K-E-L-H-K-D-V-G-D-K-L-H-M-V-Y-F-R-R-N-K-K-E-N-V-S-H-V-T-S-L-A-V-E-D-V-T-G-I-T-R-T-K-G"} +{"text": "### FUNCTION Provide a mechanistic link between auxin and plasma membrane H ### SEQUENCE -M-A-V-K-R-S-S-K-L-T-Q-T-A-M-L-K-Q-I-L-K-R-C-S-S-L-A-K-N-Q-C-Y-D-E-D-G-L-P-V-D-V-P-K-G-H-F-P-V-Y-V-G-E-K-R-S-R-Y-I-V-P-I-S-F-L-T-H-P-K-F-K-S-L-L-Q-Q-A-E-E-E-F-G-F-N-H-D-M-G-L-T-I-P-C-E-E-V-V-F-R-S-L-T-S-M-I-G"} +{"text": "### FUNCTION Cell signaling peptide that may regulate plant stress, growth, and development Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca ### SEQUENCE -M-K-L-L-I-F-A-V-I-I-S-V-V-L-F-P-V-L-V-S-S-R-T-I-K-C-D-Q-L-S-G-K-C-I-N-G-E-E-K-E-I-M-N-M-R-L-G-L-D-V-S-S-R-R-I-L-Q-A-S-R-Y-I-S-Y-E-A-L-K-K-N-L-P-D-N-R-R-G-E-P-D-Q-R-D-N-P-Y-R-R-S-C-D-V-H-S-H-C-Y-R-F-T-N"} +{"text": "### FUNCTION Possibly has a role in RNA transcription or processing during stress ### SEQUENCE -M-A-Y-A-D-N-E-Y-R-C-F-V-G-G-L-A-W-A-T-D-E-Q-S-I-E-R-C-F-N-E-F-G-E-V-F-D-S-K-I-I-I-D-R-E-T-G-R-S-K-G-F-R-F-V-T-F-K-D-E-D-S-M-R-T-A-I-D-R-M-N-G-Q-E-L-D-G-R-N-I-T-A-Q-A-R-G-S-G-T-R-G-G-M-V-G-G-Y-G-S-G-G-Y-R-G-R-R-D-Q-G-G-Y-N-R-G-G-G-G-G-Y-G-G-G-Y-G-G-D-R-R-E-G-G-Y-G-D-G-G-Y-G-G-Q-G-R-S-E-G-G-S-W-R-N"} +{"text": "### FUNCTION Elicitor of plant defense ### SEQUENCE -M-E-V-N-G-E-E-E-R-R-S-R-R-E-D-E-E-K-E-D-Y-Y-Y-S-L-L-N-S-P-C-S-V-C-N-K-F-V-Q-A-I-L-K-C-L-G-L-E-S-S-S-I-P-P-S-S-S-S-S-S-P-S-L-V-E-E-E-D-S-G-T-E-T-V-E-E-T-G-F-M-A-R-I-T-A-V-L-R-R-R-P-R-P-P-P-Y-S-S-G-R-P-G-Q-N-N"} +{"text": "### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-A-E-E-H-R-C-E-T-P-E-G-H-R-L-C-V-N-N-C-G-F-F-G-S-S-A-T-M-N-L-C-S-N-C-Y-G-D-L-C-L-K-Q-Q-Q-Q-A-S-M-K-S-T-V-E-S-S-L-S-P-V-I-A-P-V-L-E-N-Y-A-A-E-L-E-I-P-T-T-K-K-T-E-E-K-K-P-I-Q-I-P-T-E-Q-P-S-P-P-Q-R-P-N-R-C-T-V-C-R-K-R-V-G-L-T-G-F-M-C-R-C-G-T-T-F-C-G-S-H-R-Y-P-E-V-H-G-C-T-F-D-F-K-S-A-G-R-E-E-I-A-K-A-N-P-L-V-I-A-A-K-L-Q-K-I"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-A-E-I-F-E-S-V-D-K-N-K-D-G-K-I-L-W-D-E-F-A-E-A-I-R-V-F-S-P-Q-I-T-S-E-E-I-D-K-M-F-I-V-L-D-V-D-G-D-G-Q-I-D-D-V-E-F-A-S-C-L-M-V-N-G-G-G-E-K-D-T-E-E-E-V-V-M-K-E-A-F-D-L-Y-D-M-D-G-D-G-K-I-S-A-S-E-I-H-V-V-L-K-R-L-G-E-K-H-T-M-E-D-C-V-V-M-V-Q-T-V-D-K-D-S-D-G-F-V-N-F-E-E-F-K-I-M-M-N-S-N-K-E-S-H"} +{"text": "### FUNCTION Probably acts as a transcriptional activator Binds to the GCC-box pathogenesis-related promoter element May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways ### SEQUENCE -M-Q-G-T-S-K-D-N-G-G-R-H-P-L-Y-R-G-V-R-Q-R-K-N-S-N-K-W-V-S-E-I-R-E-P-R-K-P-N-R-I-W-L-G-T-F-S-T-P-E-M-A-A-I-A-Y-D-V-A-A-L-A-L-K-G-S-Q-A-E-L-N-F-P-N-S-V-S-S-L-P-A-P-T-S-M-S-P-A-D-I-Q-A-A-A-A-S-A-A-A-A-F-G-A-A-R-D-A-I-V-M-A-N-N-N-S-Q-T-S-G-V-A-C-M-N-S-S-Y-D-N-T-N-M-N-G-F-M-D-E-D-L-V-F-D-M-P-N-V-L-M-N-M-A-E-G-M-L-L-S-P-P-R-P-T-V-F-D-A-A-Y-D-A-D-G-F-P-G-G-D-D-Y-L-W-N-F-P"} +{"text": "### FUNCTION Probably acts as a transcriptional activator Binds to the GCC-box pathogenesis-related promoter element May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways ### SEQUENCE -M-E-N-S-E-N-V-P-S-Y-D-Q-N-I-N-F-T-P-N-L-T-R-D-Q-E-H-V-I-M-V-S-A-L-Q-Q-V-I-S-N-V-G-G-D-T-N-S-N-A-W-E-A-D-L-P-P-L-N-A-G-P-C-P-L-C-S-V-T-G-C-Y-G-C-V-F-P-R-H-E-A-I-I-K-K-E-K-K-H-K-G-V-R-K-K-P-S-G-K-W-A-A-E-I-W-D-P-S-L-K-V-R-R-W-L-G-T-F-P-T-A-E-M-A-A-K-A-Y-N-D-A-A-A-E-F-V-G-R-R-S-A-R-R-G-T-K-N-G-E-E-A-S-T-K-K-T-T-E-K-N"} +{"text": "### FUNCTION Probable cyclin-dependent protein kinase inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle ### SEQUENCE -M-E-Q-E-E-P-C-E-A-K-E-T-A-S-S-S-I-E-P-K-T-P-N-P-N-V-P-D-S-I-P-A-I-D-S-D-S-S-L-S-E-E-E-I-V-T-E-K-D-R-G-I-V-T-L-S-P-L-C-K-Q-R-I-D-S-A-S-I-S-D-C-V-L-V-S-D-D-E-I-I-E-S-L-Y-Q-N-L-L-R-V-I-L-S-L-Q-Q-I-Q-S-V-A-V-V-P-E-I-W-C-F-D-G-C-K-T-P-P-P-S-S-R-N-L-D-S-N-M-V-S-D-T-C-P-G-A-P-M-K-L-T-K-I-S-R-N-I-D-S-G-L-R-R-K-L-F"} +{"text": "### FUNCTION Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism ### SEQUENCE -M-G-K-N-L-G-L-V-V-S-F-Y-L-C-I-T-F-A-L-G-E-Y-F-S-E-T-R-P-I-T-P-K-Q-L-V-V-T-N-L-H-F-F-F-H-D-T-L-T-A-P-N-P-S-A-I-L-I-A-K-P-T-H-T-R-G-D-N-D-S-S-P-S-P-F-G-S-L-F-A-L-D-D-P-L-T-V-G-P-D-P-K-S-E-K-I-G-N-A-R-G-M-Y-V-S-S-G-K-H-V-P-T-L-T-M-Y-V-D-F-G-F-T-S-G-K-F-N-G-S-S-I-A-V-F-S-R-N-T-I-T-E-K-E-R-E-V-A-V-V-G-G-R-G-R-F-R-M-A-R-G-V-A-Q-L-N-T-Y-Y-V-N-L-T-N-G-D-A-I-V-E-Y-N-V-T-L-Y-H-Y"} +{"text": "### FUNCTION Probably involved in translation ### SEQUENCE -M-S-D-L-D-I-Q-I-P-T-A-F-D-P-F-S-E-A-N-A-G-D-S-G-A-A-A-G-S-K-D-Y-V-H-V-R-I-Q-Q-R-N-G-R-K-S-L-T-T-V-Q-G-L-K-K-E-F-S-Y-N-K-I-L-K-D-L-K-K-E-F-C-C-N-G-T-V-V-Q-D-P-E-L-G-Q-V-I-Q-L-Q-G-D-Q-R-K-N-V-S-N-F-L-V-Q-A-G-I-V-K-K-E-H-I-K-I-H-G-F"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-A-K-S-S-A-T-K-D-A-Q-A-L-F-H-S-L-R-S-A-Y-A-A-T-P-T-N-L-K-I-I-D-L-Y-V-I-F-A-I-S-T-A-L-I-Q-V-V-Y-M-A-I-V-G-S-F-P-F-N-S-F-L-S-G-V-L-S-C-I-G-T-A-V-L-A-V-C-L-R-I-Q-V-N-K-E-N-K-E-F-K-D-L-P-P-E-R-A-F-A-D-F-V-L-C-N-L-V-L-H-L-V-I-M-N-F-L-G"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-P-K-A-A-G-D-A-K-L-L-I-Q-S-L-N-K-A-Y-A-A-T-P-T-N-L-K-I-I-D-L-Y-V-V-F-A-V-A-T-A-L-V-Q-V-V-Y-M-G-I-V-G-S-F-P-F-N-S-F-L-S-G-V-L-S-S-I-G-T-A-V-L-G-V-C-L-R-I-Q-V-N-K-D-N-K-E-F-K-D-L-P-P-E-R-A-F-A-D-F-V-L-C-N-L-V-L-H-L-V-I-M-N-F-L-G"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-P-K-A-A-G-D-A-K-L-L-I-Q-S-L-N-K-A-Y-A-A-T-P-T-N-L-K-I-I-D-L-Y-V-V-F-A-V-V-T-A-L-L-Q-V-V-Y-M-G-I-V-G-S-F-P-F-N-S-F-L-S-G-V-L-S-C-I-G-T-A-V-L-A-V-C-H-R-I-Q-V-N-K-D-N-K-E-F-K-D-L-A-P-E-R-A-F-A-D-F-V-L-C-S-L-V-L-H-L-V-I-M-N-F-L-G"} +{"text": "### FUNCTION Necessary for protein translocation in the endoplasmic reticulum ### SEQUENCE -M-E-A-I-D-S-A-I-D-P-L-R-D-F-A-K-S-S-V-R-L-V-Q-R-C-H-K-P-D-R-K-E-F-T-K-V-A-V-R-T-A-I-G-F-V-V-M-G-F-V-G-F-F-V-K-L-V-F-I-P-I-N-N-I-I-V-G-S-S"} +{"text": "### FUNCTION Component of the signal recognition particle ### SEQUENCE -M-V-Y-I-A-S-W-D-E-F-V-D-R-S-V-Q-L-F-R-A-D-P-E-S-T-R-Y-V-M-K-Y-R-H-C-D-G-K-L-V-L-K-V-T-D-N-K-E-C-L-K-F-K-T-D-Q-A-Q-E-A-K-K-M-E-K-L-N-N-I-F-F-T-L-M-A-R-G-P-D-V-D-L-S-E-V-T-G-K-E-Q-M-E-T-Q-P-A-K-K-G-R-G-R-K-Q"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-E-D-S-S-L-L-S-P-I-S-L-L-T-I-V-I-F-L-F-I-L-N-L-M-M-I-I-Q-D-F-S-S-S-F-P-F-R-F-H-L-F-F-S-N-A-Y-I-L-F-T-S-I-R-N-N-K-Q-N-T-E-L-P-I-I-K-K-V-V-V-P-N-R-A-D-I-K-T-S-V-E-E-V-K-A-I-I-D-D-S-E-A-L-Y-E-C-L-I-E-E-G-E-E-Y-L-L-E-K-N-E-M-M-G-K-E-I-V-K-E-A-F-R-L-F-D-E-N-Q-D-G-F-I-D-E-N-E-L-K-H-V-L-S-L-L-G-Y-D-E-C-T-K-M-E-C-R-K-M-V-K-V-Y-D-E-N-R-D-G-K-I-D-F-Y-E-F-V-K-L-I-E-K-S-F-S"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-E-H-L-M-C-E-I-D-G-Q-H-L-T-A-A-A-I-I-G-H-E-G-G-I-W-A-Q-S-D-S-F-P-Q-V-K-P-E-Q-T-A-A-I-M-R-D-F-A-E-P-G-S-L-A-P-T-G-L-F-L-G-D-G-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-S-G-G-V-T-I-K-K-T-N-M-A-L-I-V-G-I-Y-D-E-P-M-T-P-G-Q-C-N-M-V-V-E-R-L-G-D-Y-L-Y-D-Q-G-F"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-E-H-L-M-C-E-I-D-G-Q-H-L-T-A-A-A-I-I-G-H-D-G-S-I-W-A-Q-S-E-S-F-P-Q-V-K-S-E-Q-I-T-G-V-M-N-D-F-A-E-P-G-S-L-A-P-T-G-L-F-L-G-D-N-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-S-G-G-V-T-I-K-K-T-N-M-A-L-I-V-G-I-Y-D-E-P-M-T-P-G-Q-C-N-M-V-V-E-R-L-G-D-Y-L-Y-D-Q-G-F"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-D-H-L-M-C-D-V-D-G-Q-H-L-T-A-S-A-I-V-G-H-D-G-S-I-W-A-Q-S-A-G-F-P-Q-F-K-P-E-E-I-T-G-I-M-N-D-F-A-E-P-G-S-L-A-P-T-G-L-Y-L-A-G-M-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-S-G-G-V-T-I-K-K-T-G-Q-A-L-I-F-G-I-Y-E-E-P-M-T-P-G-Q-C-N-M-V-V-E-R-M-G-D-Y-L-V-D-Q-G-L"} +{"text": "### FUNCTION Catalytic subunit of the peripheral V1 complex of vacuolar ATPase V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells ### SEQUENCE -M-T-S-N-R-G-Q-G-G-I-Q-Q-L-L-A-A-E-Q-E-A-Q-H-I-V-A-A-A-R-N-A-K-M-A-R-L-K-Q-A-K-E-E-A-E-R-E-I-A-E-Y-R-A-Q-V-E-R-E-F-Q-R-K-L-A-E-S-V-G-D-S-G-A-N-V-K-R-L-E-Q-E-T-E-V-K-I-H-H-L-K-A-G-A-E-K-I-Q-Y-D-V-V-Q-M-F-L-K-H-V-T-T-V-K-N"} +{"text": "### FUNCTION Not yet known ### SEQUENCE -M-T-A-I-A-K-S-A-A-K-V-T-C-D-G-A-N-T-S-F-I-I-S-A-S-T-A-A-L-L-A-L-G-R-F-V-F-L-P-F-Q-R-S-M-V-S-R-H-G-L-P-E-Q-N-G-V-P-T-T-R-R-V-T-A-V-R-R-R-W-W-S-M-L-K-T-N-D-P-A-G-F-T-L-V-D-V-L-A-W-G-A-L-G-H-A-V-G-F-F-I-L-A-T-A-T-N-G-Y-N-G-F-Q"} +{"text": "### FUNCTION Probably involved in translation ### SEQUENCE -M-S-E-L-D-S-Q-V-P-T-A-F-D-P-F-A-D-A-N-A-E-D-S-G-A-G-T-K-E-Y-V-H-I-R-V-Q-Q-R-N-G-R-K-S-L-T-T-V-Q-G-L-K-K-E-Y-S-Y-T-K-I-L-K-D-L-K-K-E-F-C-C-N-G-T-V-V-Q-D-S-E-L-G-Q-V-I-Q-L-Q-G-D-Q-R-K-N-V-S-T-F-L-V-Q-A-G-L-V-K-K-D-D-I-Q-I-H-G-F"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-N-H-L-L-C-E-I-E-G-D-H-L-S-S-A-A-I-L-G-Q-D-G-G-V-W-A-Q-S-S-H-F-P-Q-F-K-P-E-E-I-T-A-I-M-N-D-F-A-E-P-G-S-L-A-P-T-G-L-Y-L-G-G-T-K-Y-M-V-I-Q-G-E-P-G-A-I-I-P-G-K-K-G-P-G-G-V-T-I-E-K-T-N-Q-A-L-I-I-G-I-Y-D-K-P-M-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-I-D-T-G-L"} +{"text": "### FUNCTION Destroys radicals which are normally produced within the cells and which are toxic to biological systems ### SEQUENCE -M-V-K-A-V-A-V-L-G-S-S-E-G-V-K-G-T-I-Y-F-T-Q-E-G-D-G-P-T-T-V-T-G-S-I-S-G-L-K-P-G-L-H-G-F-H-V-H-A-L-G-D-T-T-N-G-C-M-S-T-G-P-H-F-N-P-A-G-N-E-H-G-A-P-E-D-E-T-R-H-A-G-D-L-G-N-V-T-V-G-E-D-G-T-V-N-V-N-I-V-D-S-Q-I-P-L-S-G-S-N-S-I-I-G-R-A-V-V-V-H-A-D-P-D-D-L-G-K-G-G-H-E-L-S-K-T-T-G-N-A-G-G-R-V-A-C-G-I-I-G-L-Q-G"} +{"text": "### FUNCTION May play a role in chromosome segregation through establishment of sister chromatid cohesion ### SEQUENCE -M-D-S-V-L-T-N-K-N-P-I-I-Y-P-K-R-T-R-R-Y-R-T-D-Q-S-S-T-D-E-F-S-S-T-N-R-I-R-D-I-K-D-P-E-H-P-E-L-S-L-E-D-L-N-V-L-T-E-E-S-V-E-V-D-D-H-K-S-Y-V-R-I-T-F-T-P-T-L-P-H-C-H-L-P-T-H-I-G-L-C-I-L-V-K-L-V-Q-S-L-P-A-R-F-K-V-D-V-R-V-A-P-G-S-H-D-K-E-T-T-V-N-K-Q-L-G-D-K-E-R-V-T-A-A-L-E-N-P-E-L-V-A-L-L-N-K-M-M-Q-V-C"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-N-N-M-S-L-S-D-I-F-E-R-F-D-T-S-K-D-G-K-I-S-W-E-E-F-R-D-A-I-H-A-L-S-P-S-I-P-S-E-K-L-V-E-M-F-I-Q-L-D-T-N-G-D-G-Q-V-D-A-A-K-F-A-S-C-M-D-Q-T-A-Q-S-S-G-G-D-V-E-K-E-L-K-D-A-F-K-L-Y-D-I-N-C-D-G-K-I-S-A-N-E-L-H-V-V-M-T-R-L-G-E-K-C-T-V-E-S-C-V-G-M-V-Q-A-I-D-V-D-G-D-G-Y-I-R-F-V-G-V"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-S-A-K-R-V-F-E-K-F-D-K-N-K-D-G-K-L-S-L-D-E-F-R-E-V-A-L-A-F-S-P-Y-F-T-Q-E-D-I-V-K-F-F-E-E-I-D-V-D-G-N-G-E-L-N-A-D-E-F-T-S-C-I-E-K-M-L-K-E-V-F-V-F-C-D-V-D-G-D-G-K-I-P-A-S-E-S-Y-V-T-M-T-S-L-G-K-K-F-T-E-E-T-S-A-E-K-V-R-A-A-D-V-D-G-D-G-Y-L-N-F-D-E-F-M-A-L-V-I-G-D-I"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-A-D-A-T-E-K-A-E-H-D-R-I-F-K-K-F-D-A-N-G-D-G-K-I-S-A-A-E-L-G-D-A-L-K-N-L-G-S-V-T-H-E-D-I-K-R-M-M-A-E-I-D-T-D-G-D-G-Y-I-S-Y-Q-E-F-I-D-F-A-S-A-N-R-G-L-M-K-D-V-A-K-I-F"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-D-Q-A-E-L-A-R-I-F-Q-M-F-D-R-N-G-D-G-K-I-T-K-Q-E-L-N-D-S-L-E-N-L-G-I-Y-I-P-D-K-D-L-V-Q-M-I-E-K-I-D-L-N-G-D-G-Y-V-D-I-E-E-F-G-G-L-Y-Q-T-I-M-E-E-R-D-E-E-E-D-M-R-E-A-F-N-V-F-D-Q-N-R-D-G-F-I-T-V-E-E-L-R-S-V-L-A-S-L-G-L-K-Q-G-R-T-L-E-D-C-K-R-M-I-S-K-V-D-V-D-G-D-G-M-V-N-F-K-E-F-K-Q-M-M-K-G-G-G-F-A-A-L-G-S-N-L"} +{"text": "### FUNCTION Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism ### SEQUENCE -M-A-S-L-Y-L-L-L-L-L-P-L-F-L-A-L-I-L-A-A-T-I-T-E-S-K-S-F-S-T-T-V-K-A-P-Y-P-G-H-K-P-D-K-L-T-H-L-H-F-Y-F-H-D-I-V-S-G-D-K-P-T-S-V-Q-V-A-N-G-P-T-T-N-S-S-A-T-G-F-G-L-V-A-V-V-D-D-K-L-T-V-G-P-E-I-T-S-E-E-V-G-R-A-Q-G-M-Y-A-S-A-D-Q-N-K-L-G-L-L-M-A-F-N-L-V-F-T-K-G-K-F-S-D-S-T-V-A-M-Y-G-R-N-P-V-L-S-K-V-R-E-M-P-I-I-G-G-T-G-A-F-R-F-G-R-G-Y-A-L-A-K-T-L-V-F-N-I-T-S-G-D-A-V-V-E-Y-N-V-Y-I-W-H"} +{"text": "### FUNCTION May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil Probably interacts with both lipid and phospholipid moieties of lipid bodies May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth ### SEQUENCE -M-A-D-V-R-T-H-S-H-Q-L-Q-V-H-P-Q-R-Q-H-E-G-G-I-K-V-L-Y-P-Q-S-G-P-S-S-T-Q-V-L-A-V-F-V-G-V-P-I-G-G-T-L-L-T-I-A-G-L-T-L-A-G-S-V-I-G-L-M-L-A-F-P-L-F-L-I-F-S-P-V-I-V-P-A-A-F-V-I-G-L-A-M-T-G-F-L-A-S-G-A-I-G-L-T-G-L-S-S-M-S-W-V-L-N-Y-I-R-R-A-G-Q-H-I-P-E-E-L-E-E-A-K-H-R-L-A-D-M-A-E-Y-V-G-Q-R-T-K-D-A-G-Q-T-I-E-D-K-A-H-D-V-R-E-A-K-T-F-D-V-R-D-R-D-T-T-K-G-T-H-N-V-R-D-T-K-T-T"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-D-H-L-M-V-D-F-E-G-Q-G-Q-H-L-A-A-A-A-I-L-G-H-D-G-S-V-W-A-Q-S-P-H-F-P-K-F-K-P-E-E-I-T-N-I-M-K-D-F-D-E-P-G-F-L-A-P-T-G-L-F-L-A-G-I-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-S-G-G-I-T-I-K-K-T-N-Q-A-L-I-F-G-L-Y-E-E-P-V-T-P-G-Q-C-N-M-V-V-E-K-I-G-D-Y-L-V-D-Q-G-Y"} +{"text": "### FUNCTION Probable lipid transfer protein ### SEQUENCE -M-A-Q-T-T-T-L-I-L-L-L-A-T-L-L-V-A-A-T-T-V-S-G-Q-G-P-H-I-P-L-A-P-S-P-S-V-N-E-A-M-N-C-A-A-G-L-A-V-C-L-P-A-I-T-Q-R-G-P-P-S-Q-E-C-C-T-A-V-E-T-A-L-T-T-Q-L-S-C-L-C-G-F-I-K-S-P-M-L-L-I-P-F-N-V-T-D-F-N-A-L-F-S-K-T-C-G-L-T-T-D-P-N-L-C-S-E-T-A-A-Q-A-P-L-P-K-T-A-A-P-V-P-G-A-P-K-S-D-K-D-A-A-S-K-L-A-G-T-G-L-V-G-I-V-V-I-T-I-A-A-M-F-Y"} +{"text": "### FUNCTION May act as a carbohydrate transporter ### SEQUENCE -M-G-R-S-M-V-L-I-S-A-V-V-L-A-F-L-V-A-A-P-I-P-E-V-T-A-K-K-Y-L-V-G-D-K-K-F-W-N-P-N-I-N-Y-T-L-W-A-Q-G-K-H-F-Y-V-G-D-W-L-Y-F-V-F-Y-R-D-Q-H-N-I-L-E-V-N-K-A-D-Y-E-K-C-I-S-N-R-P-I-R-N-Y-T-R-G-A-G-R-D-I-V-P-L-Y-E-T-R-R-Y-Y-L-L-D-G-R-G-G-C-V-Q-G-M-K-L-D-V-L-V-E-T-P-P-P-P-P-P-F-T-P-P-P-P-A-Q"} +{"text": "### FUNCTION Probably acts as a transcriptional activator Binds to the GCC-box pathogenesis-related promoter element May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways ### SEQUENCE -M-Q-D-S-S-S-H-E-S-Q-R-N-L-R-S-P-V-P-E-K-T-G-K-S-S-K-T-K-N-E-Q-K-G-V-S-K-Q-P-N-F-R-G-V-R-M-R-Q-W-G-K-W-V-S-E-I-R-E-P-R-K-K-S-R-I-W-L-G-T-F-S-T-P-E-M-A-A-R-A-H-D-V-A-A-L-A-I-K-G-G-S-A-H-L-N-F-P-E-L-A-Y-H-L-P-R-P-A-S-A-D-P-K-D-I-Q-E-A-A-A-A-A-A-A-V-D-W-K-A-P-E-S-P-S-S-T-V-T-S-S-P-V-A-D-D-A-F-S-D-L-P-D-L-L-L-D-V-N-D-H-N-K-N-D-G-F-W-D-S-F-P-Y-E-D-P-F-F-L-E-N-Y"} +{"text": "### FUNCTION Probable common Sm protein, is found in U1 and U2 snRNPs and may be part of the spliceosome ### SEQUENCE -M-A-T-I-P-V-N-P-K-P-F-L-N-N-L-T-G-K-T-V-I-V-K-L-K-W-G-M-E-Y-K-G-F-L-A-S-V-D-S-Y-M-N-L-Q-L-G-N-T-E-E-Y-I-D-G-Q-L-T-G-N-L-G-E-I-L-I-R-C-N-N-V-L-Y-V-R-G-V-P-E-D-E-E-L-E-D-A-D-Q-D"} +{"text": "### FUNCTION Probable lipid transfer protein ### SEQUENCE -M-A-V-A-V-T-A-V-L-F-L-A-V-V-I-A-P-Q-W-T-E-T-K-K-P-P-R-P-S-D-T-S-D-T-S-G-T-S-G-R-D-R-R-T-M-C-P-L-S-I-P-G-I-V-Q-N-C-Y-A-T-L-N-A-F-P-S-K-E-C-C-K-D-L-K-T-A-S-K-R-E-V-T-C-L-C-N-N-V-I-A-H-P-D-P-L-Y-T-N-T-N-Q-V-N-K-A-C-G-V-L-D-K-Y-A-C-D-A-G-N-S-N-G-G-A-T-K-K-I-V-A-S-M-G-L-F-G-V-V-A-S-L-F-F"} +{"text": "### FUNCTION May be involved in heavy metals transport ### SEQUENCE -M-N-L-S-S-N-D-Q-P-S-Q-G-R-I-K-A-K-D-W-S-T-D-L-C-E-C-W-M-D-I-N-S-C-C-L-T-C-W-C-P-C-V-A-F-G-R-I-A-E-V-V-D-R-G-S-T-S-C-G-V-S-G-A-M-Y-M-I-I-F-M-L-T-G-Y-G-G-S-S-L-Y-S-C-F-Y-R-T-K-L-R-A-Q-Y-N-L-K-E-R-P-C-C-D-C-C-V-H-F-C-C-E-P-C-A-L-C-Q-E-Y-R-Q-L-Q-H-N-R-D-L-D-L-V-I-G-W-H-G-N-M-E-R-H-A-R-L-A-A-S-T-P-S-A-P-P-L-Q-A-P-M-S-R-L-V"} +{"text": "### FUNCTION May be involved in heavy metals transport ### SEQUENCE -M-Y-G-N-G-P-V-F-K-A-E-G-T-S-F-R-D-Q-P-Y-A-E-Q-L-P-Q-G-L-W-T-T-G-L-C-D-C-H-E-D-A-H-I-C-V-Q-T-A-I-M-P-C-V-S-F-A-Q-N-V-E-I-V-N-R-G-T-I-P-C-M-N-A-G-L-I-H-L-A-L-G-F-I-G-C-S-W-L-Y-A-F-P-N-R-S-R-L-R-E-H-F-A-L-P-E-E-P-C-R-D-F-L-V-H-L-F-C-T-P-C-A-I-C-Q-E-S-R-E-L-K-N-R-G-A-D-P-S-I-G-W-L-S-N-V-E-K-W-S-R-E-K-V-T-P-P-I-V-V-P-G-M-I-R"} +{"text": "### FUNCTION E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage ### SEQUENCE -M-E-G-W-D-P-N-T-K-S-T-L-T-R-I-P-L-L-T-T-K-A-G-P-R-D-G-A-A-W-T-Q-R-L-K-E-E-Y-K-S-L-I-A-Y-T-Q-M-N-K-S-N-D-N-D-W-F-R-I-S-A-S-N-P-E-G-T-R-W-T-G-K-C-W-Y-V-H-N-L-L-K-Y-E-F-D-L-Q-F-D-I-P-I-T-Y-P-A-T-A-P-E-L-E-L-P-E-I-D-G-K-T-Q-K-M-Y-R-G-G-K-I-C-L-T-V-H-F-K-P-L-W-A-K-N-C-P-R-F-G-I-A-H-A-L-C-L-G-L-A-P-W-L-A-A-E-I-P-I-L-V-D-S-G-A-I-K-H-K-D-D-A-A-T-S-A-E-S"} +{"text": "### FUNCTION Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I ### SEQUENCE -M-A-S-V-A-A-A-A-V-S-V-P-S-F-S-G-L-K-A-E-T-K-A-A-P-A-R-L-S-S-T-S-V-V-R-M-A-P-V-V-R-A-S-A-S-S-D-A-L-K-T-V-G-K-A-L-L-A-A-S-S-S-L-L-L-V-A-S-A-N-A-A-T-V-K-M-G-G-D-D-G-A-L-G-F-Y-P-K-D-I-S-V-A-A-G-E-S-V-T-F-V-N-N-K-G-F-P-H-N-V-V-F-D-E-D-A-V-P-A-G-V-K-T-E-D-I-N-H-E-D-Y-L-N-G-P-N-E-S-F-S-I-T-F-K-T-P-G-T-Y-E-F-Y-C-E-P-H-Q-G-A-G-M-K-G-V-V-T-V-S"} +{"text": "### FUNCTION This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport ### SEQUENCE -M-A-G-G-R-I-A-H-A-T-L-K-G-P-S-V-V-K-E-I-C-I-G-L-T-L-G-L-V-A-G-G-L-W-K-M-H-H-W-N-E-Q-R-K-T-R-S-F-Y-D-M-L-E-K-G-Q-I-S-V-V-V-E-E"} +{"text": "### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-G-S-E-E-N-N-S-T-S-F-P-P-T-E-P-K-L-C-D-N-G-C-G-F-F-G-S-P-S-N-M-N-L-C-S-K-C-Y-R-S-L-R-A-E-E-D-Q-T-A-V-A-K-A-A-V-K-N-S-L-K-L-P-S-C-S-I-I-A-P-G-Q-K-H-P-L-E-I-K-P-A-H-L-E-T-V-V-V-T-A-E-P-S-S-V-P-V-A-A-E-Q-D-E-A-E-P-S-R-P-V-R-P-N-N-R-C-F-S-C-N-K-K-V-G-V-M-G-F-K-C-K-C-G-S-T-F-C-G-S-H-R-Y-P-E-K-H-E-C-S-F-D-F-K-E-V-G-R-D-A-I-A-K-A-N-P-L-V-K-A-D-K-V-Q-R-I"} +{"text": "### FUNCTION Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism ### SEQUENCE -M-A-N-Q-I-Y-L-F-S-L-I-C-L-S-V-L-L-C-Q-S-Y-T-V-S-S-F-Q-K-S-L-D-L-A-K-P-C-K-R-F-V-L-H-L-H-D-I-A-Y-D-G-D-N-A-A-N-A-T-S-A-A-I-V-N-P-L-G-L-G-D-F-S-F-G-K-F-V-I-M-D-D-P-V-T-M-D-Q-N-Y-L-S-K-P-V-A-R-V-Q-G-F-F-C-Y-H-G-K-A-T-Y-D-A-W-I-A-W-T-V-V-F-N-S-T-Q-H-K-G-A-F-T-I-M-G-E-N-P-F-M-E-P-T-R-D-L-P-I-V-G-G-T-G-D-F-I-M-T-R-G-I-A-T-L-T-T-D-H-I-D-G-S-K-Y-F-R-V-K-L-D-I-K-L-Y-E-C-Y-H"} +{"text": "### FUNCTION Controls stomatal patterning ### SEQUENCE -M-V-W-S-S-N-M-S-S-F-L-L-I-L-L-I-L-N-S-T-H-F-S-L-M-A-N-G-R-P-E-P-D-S-V-E-F-T-K-S-G-D-Q-D-V-K-M-M-M-R-G-L-I-G-S-R-P-P-R-C-E-R-V-R-C-R-S-C-G-H-C-E-A-I-Q-V-P-T-N-P-Q-T-K-L-H-S-P-L-T-T-S-S-S-S-S-S-E-T-I-H-L-D-Y-T-R-G-D-D-S-T-N-Y-K-P-M-S-W-K-C-K-C-G-N-S-I-Y-N-P"} +{"text": "### FUNCTION This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport ### SEQUENCE -M-A-T-A-I-V-R-S-A-L-S-R-A-V-T-R-A-A-P-K-T-S-V-A-P-K-R-N-F-S-S-S-A-G-H-D-D-A-Y-E-A-A-K-W-E-K-I-T-Y-L-G-I-A-S-C-T-A-L-A-V-Y-V-L-S-K-G-H-H-H-G-E-D-P-P-A-Y-P-H-M-H-I-R-N-K-E-F-P-W-G-P-D-G-L-F-E-V-K-H-N-K-E-H"} +{"text": "### FUNCTION Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 26 nm in diameter, and consisting of 89 capsid proteins dimers Involved in viral genome encapsidation through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome Binding of the capsid proteins to the viral RNA induces a conformational change required for efficient T=3 shell formation The capsid contains also 1 copy of the A2 maturation protein ### SEQUENCE -M-A-K-L-Q-A-I-T-L-S-G-I-G-K-N-G-D-V-T-L-N-L-N-P-R-G-V-N-P-T-N-G-V-A-A-L-S-E-A-G-A-V-P-A-L-E-K-R-V-T-I-S-V-S-Q-P-S-R-N-R-K-N-Y-K-V-Q-V-K-I-Q-N-P-T-S-C-T-A-S-G-T-C-D-P-S-V-T-R-S-A-Y-A-D-V-T-F-S-F-T-Q-Y-S-T-D-E-E-R-A-L-V-R-T-E-L-K-A-L-L-A-D-P-M-L-I-D-A-I-D-N-L-N-P-A-Y"} +{"text": "### FUNCTION Involved in T4 DNA replication Important for the priming of leading strand DNA synthesis at oriE Binds to ssDNA ### SEQUENCE -M-V-I-F-Q-L-E-Y-P-L-H-H-L-V-L-F-E-V-D-A-D-Q-P-H-E-H-E-H-D-L-I-L-M-G-P-F-Y-L-Q-Q-H-R-Q-T-N"} +{"text": "### FUNCTION Involved in O antigen modification Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane ### SEQUENCE -M-L-K-L-F-A-K-Y-T-S-I-G-V-L-N-T-L-I-H-W-V-V-F-G-V-C-I-Y-A-A-H-T-N-Q-A-M-A-N-F-A-G-F-V-V-A-V-S-F-S-F-F-A-N-A-K-F-T-F-K-A-S-T-T-T-M-R-Y-M-L-Y-V-G-F-M-G-T-L-S-A-T-V-G-W-V-A-D-R-C-S-L-P-P-I-V-T-L-V-T-F-S-A-I-S-L-V-C-G-F-V-Y-S-K-F-I-V-F-R-D-A-K"} +{"text": "### FUNCTION Nuclease ### SEQUENCE -M-R-L-I-R-E-D-S-I-E-K-H-L-V-S-E-V-R-K-I-G-G-I-A-Y-K-F-V-S-P-G-R-R-G-V-P-D-R-L-V-A-L-P-N-G-K-I-I-F-V-E-C-K-A-P-G-E-K-P-T-P-Y-Q-L-R-E-H-A-R-L-F-A-L-G-H-Q-V-I-V-L-D-S-Q-D-L-S-S-I-L-P-A-V-N"} +{"text": "### FUNCTION Excisionase and integrase are necessary for the excision of prophage from the host genome by site-specific recombination ### SEQUENCE -M-R-N-V-M-N-K-A-T-L-T-R-Q-E-A-A-K-I-I-G-I-S-E-D-T-L-S-N-W-C-K-L-G-I-I-S-Y-Q-R-K-N-P-Y-K-K-K-S-P-Y-L-F-T-K-E-A-C-I-E-A-V-K-N-S-I-N-T-L-S-E-S-E-I-D-V-I-R-S-K-K-C-Q-S-S-N-V-V-K-F-G-T-A-V-T-Q-H-R-A-E-K-E-L-R-N-H-L-A-Q-R-T-K-N-K-L-R-S-Y-T-T-N-E-E-L-N-Y-G-E"} +{"text": "### FUNCTION Component of the cylindrical core that assembles on the inner surface of the capsid during procapsid formation Required for stabilization of the condensed DNA within the capsid ### SEQUENCE -M-T-K-P-L-T-K-G-E-I-V-L-F-A-L-R-K-A-G-I-A-S-E-A-T-N-I-D-V-E-P-Q-S-F-E-E-G-I-N-D-L-E-D-L-M-A-E-L-Q-I-T-F-G-D-L-G-Y-Q-F-S-A-E-E-E-N-P-T-S-D-D-A-S-G-L-P-R-K-Y-K-Q-V-M-G-Y-Q-L-M-L-R-M-L-S-D-Y-G-I-E-P-T-P-R-Q-E-A-S-A-A-A-A-Y-D-A-L-L-T-D-T-L-S-V-P-S-I-A-R-R-G-D-M-P-V-G-Q-G-N-N-Y-T-A-L-G-T-A-S-Y-Y-V-E-R-G-F-H-A-K-N-T-D-P-V-S"} +{"text": "### FUNCTION Positively regulates expression of some phage genes Bacterial host RNA polymerase modified by antitermination proteins transcribes through termination sites that otherwise prevent expression of the regulated genes ### SEQUENCE -M-R-R-D-I-Q-Q-V-L-E-R-W-G-T-W-A-R-D-N-N-T-G-I-D-W-S-P-I-A-A-G-F-K-G-L-L-P-L-R-P-S-M-R-P-S-C-S-D-E-D-G-R-I-I-D-N-C-V-S-Q-L-Q-Q-V-R-Q-P-E-E-L-S-L-I-I-A-Y-Y-V-K-G-Y-S-K-R-A-I-A-R-R-R-R-V-D-E-G-L-I-R-A-K-L-L-I-A-E-G-F-I-D-G-C-L-S-L-L-A-V-R-L-D-M-D-P-E-V-K-M-Y-S-P-Q-K-S-G-K-R-I-S-A-V-R-K-K-F-V-N-V-L"} +{"text": "### FUNCTION May stop tail tube polymerization by capping the rapidly polymerizing tail tube once it has reached its requisite length and prevent its depolymerization ### SEQUENCE -M-L-E-E-T-E-A-A-L-L-A-R-V-R-E-L-F-G-A-T-L-R-Q-V-E-P-L-T-G-T-W-T-N-E-D-V-H-R-L-F-L-A-P-P-S-V-F-L-A-W-M-G-C-G-E-G-R-T-R-R-E-V-E-S-R-W-A-F-F-V-V-A-E-L-L-N-G-E-P-V-N-R-P-G-I-Y-Q-I-V-E-R-L-I-A-G-V-N-G-Q-T-F-G-P-T-T-G-M-R-L-T-Q-V-R-N-L-C-D-D-N-R-I-N-A-G-V-V-L-Y-G-V-L-F-S-G-T-T-P-L-P-S-V-V-D-L-D-S-L-D-D-Y-E-R-H-W-Q-T-W-K-F-P-D-E-T-P-E-F-A-A-H-I-N-V-N-Q-E-K-D-H-D-A-E-N"} +{"text": "### FUNCTION The terminase small subunit binds to the packaging initiation site Once the capsid is packaged with the DNA, the terminase complex is substituted by neck proteins ### SEQUENCE -M-D-R-K-T-R-G-R-A-S-K-V-D-L-L-P-E-N-V-R-K-T-L-H-E-M-L-R-D-K-A-I-P-Q-A-R-I-L-E-E-I-N-A-L-I-E-D-A-G-L-P-D-E-M-K-L-S-R-S-G-L-N-R-Y-A-T-N-V-E-Q-V-G-H-N-L-R-Q-M-R-E-M-T-S-A-L-T-A-E-L-G-D-K-P-M-G-E-T-T-K-L-I-L-E-M-A-R-S-Q-L-F-K-A-M-M-R-Q-I-E-N-P-E-S-D-V-D-I-D-L-L-K-N-A-M-L-A-A-Q-R-L-E-S-T-A-M-S-S-H-R-R-E-K-E-I-R-Q-A-F-A-E-E-A-A-N-A-V-S-E-E-L-R-G-Q-D-G-I-S-E-E-L-E-Q-R-I-R-D-V-L-L-G-K-A"} +{"text": "### FUNCTION Facilitates the release of the SAR-endolysin ### SEQUENCE -M-D-L-I-S-V-L-A-L-W-P-Y-L-L-P-V-V-A-G-G-A-V-W-A-M-R-R-S-F-A-S-T-E-R-V-E-R-L-E-N-R-M-T-E-M-E-T-R-Y-A-S-I-P-G-T-E-D-V-H-E-M-R-L-R-I-A-E-L-S-G-D-I-R-V-L-S-Q-R-V-Q-S-F-S-H-Q-L-E-L-L-L-E-N-A-V-N-R-S-N-S"} +{"text": "### FUNCTION Component of the spanin complex that disrupts the host outer membrane and causes cell lysis during virus exit The spanin complex conducts the final step in host lysis by disrupting the outer membrane after endolysin action has degraded the host peptidoglycans Host outer membrane disruption is possibly due to local fusion between the inner and outer membrane performed by the spanin complex ### SEQUENCE -M-T-F-A-S-K-S-L-L-L-A-A-V-F-T-A-V-L-S-G-G-L-W-H-R-L-D-S-T-R-H-D-N-Q-T-L-R-R-E-L-Q-T-E-Q-Q-A-R-H-T-A-E-W-L-L-H-G-Q-E-Q-T-M-Q-V-F-S-A-I-R-A-A-N-R-A-A-R-L-A-D-E-T-E-H-H-D-A-K-E-K-I-T-T-A-I-T-G-D-N-C-S-T-R-P-V-P-A-V-A-A-D-R-L-R-E-L-E-K-R-T-R-A-I-G-G-D-P-A-R-N"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-I-M-F-L-Y-S-S-F-S-M-I-L-F-I-L-G-L-F-C-F-V-S-N-R-K-H-L-L-S-M-L-L-S-L-E-F-I-V-L-I-L-F-F-M-L-F-I-Y-L-N-L-M-N-Y-E-N-Y-F-S-M-M-F-L-T-F-S-V-C-E-G-A-L-G-L-S-I-L-V-S-M-I-R-T-H-G-N-D-Y-F-Q-S-F-S-I-M"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-P-Q-L-E-P-A-P-W-F-S-M-L-T-V-S-W-L-I-I-L-L-L-I-M-P-T-I-M-F-Y-Q-T-Q-N-T-V-S-A-Q-Q-A-T-K-P-K-Q-P-T-W-T-W-P-W-H"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-P-Q-L-N-P-N-P-W-F-Y-I-M-L-M-S-W-L-T-F-S-L-I-I-Q-P-E-L-L-S-F-T-L-T-N-P-L-S-N-K-T-S-T-T-T-R-S-S-P-W-T-W-P-W-T"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-P-Q-L-N-P-N-P-W-F-F-T-M-L-T-T-W-L-T-F-L-L-L-I-Q-P-K-L-L-S-F-I-M-T-N-P-P-I-N-K-S-S-K-H-T-K-T-P-S-W-T-W-P-W-T"} +{"text": "### FUNCTION Mitochondrial DNA endonuclease involved in intron homing ### SEQUENCE -M-I-Y-E-F-F-N-K-N-G-Y-C-T-N-N-I-P-R-K-Y-I-V-K-L-K-H-N-D-D-V-K-D-F-E-R-Y-E-F-V-T-Y-T-F-R-S-F-K-Y-I-Y-E-M-F-Y-K-K-Q-K-K-V-L-H-L-E-K-I-K-E-Y-L-D-E-R-A-L-A-H-W-I-M-D-D-G-G-Y-T-G-A-G-I-R-I-A-T-N-A-F-T-L-K-E-V-M-F-L-K-E-L-L-E-D-K-F-K-L-K-C-T-I-Q-E-I-Y-I-K-D-K-W-S-I-Y-I-T-K-D-S-M-T-H-L-I-S-I-I-K-P-Y-M-H-P-S-M-Y-Y-K-L-G-I-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-D-T-T-G-R-I-P-L-W-L-I-S-T-V-T-G-T-L-V-I-G-L-M-G-I-F-F-Y-G-S-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-N-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-S-F-N"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-M-L-N-L-L-Q-Y-P-V-I-K-T-P-K-A-T-R-L-L-E-N-N-Q-Y-S-F-D-I-D-K-K-L-T-K-P-Q-I-K-K-L-V-E-E-Y-F-N-I-K-V-L-A-I-N-T-H-R-P-P-R-K-I-K-R-S-G-S-A-P-R-S-K-R-V-I-I-T-V-S-A-N-I-N-L-L-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-R-T-A-K-K-R-I-V-M-P-D-P-V-Y-K-N-S-L-L-E-L-I-V-R-Q-V-M-R-N-G-K-K-L-L-A-Y-R-I-M-Y-N-S-M-I-K-I-A-E-M-T-Q-K-D-P-L-D-V-L-E-K-A-I-R-N-V-T-P-L-I-E-V-K-A-R-R-V-G-G-S-T-Y-Q-V-P-L-E-V-L-P-E-R-G-T-T-L-A-I-R-W-I-L-A-A-C-R-K-N-R-G-K-P-M-Y-I-K-L-T-N-E-L-I-D-A-S-N-K-S-G-S-A-I-K-K-K-D-E-I-H-R-M-A-E-A-N-K-A-F-A-K-Q-R-F"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-V-K-R-G-N-I-A-R-N-R-R-N-E-I-L-D-L-A-K-G-F-R-G-S-S-S-K-L-Y-R-T-A-Q-Q-R-T-I-K-A-L-T-N-S-Y-K-D-R-K-N-K-K-R-E-F-V-K-I-W-V-S-R-I-N-A-A-V-R-L-S-G-L-N-Y-S-S-F-Q-N-Q-L-K-F-H-K-I-R-L-N-R-K-I-C-S-Q-I-A-L-Q-D-Q-E-S-F-T-K-L-L-D-L-I-I"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-I-L-K-I-L-I-M-I-P-D-G-I-F-W-N-N-K-A-E-E-I-I-L-P-T-N-T-G-Q-I-G-I-L-K-N-H-A-P-L-I-T-A-L-D-I-G-V-I-L-I-R-T-D-K-K-W-V-P-F-I-I-M-G-G-F-A-L-I-K-Q-N-K-I-T-I-L-V-N-G-A-E-S-A-G-T-L-K-L-V-Q-S-E-A-A-F-Q-E-A-T-N-K-L-E-N-A-K-S-K-K-Q-Y-V-D-A-L-F-L-F-K-C-A-K-A-R-Y-Q-A-A-K-Q-L-V-S"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-T-L-N-L-C-V-L-T-P-N-R-T-V-W-D-S-E-V-K-E-I-I-L-S-T-N-S-G-Q-I-G-V-L-K-N-H-A-P-I-A-T-A-L-D-I-G-I-L-K-I-R-L-T-N-Q-Q-W-V-T-M-A-L-M-G-G-F-A-R-I-G-N-N-E-I-T-I-L-V-N-D-A-E-K-S-I-D-I-D-P-Q-E-A-Q-Q-T-L-K-I-A-E-A-N-L-N-K-A-E-G-K-R-Q-T-I-E-A-N-L-A-L-R-R-A-R-T-R-V-E-T-I-L-E-S-I-N-R-F"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-I-F-V-Y-T-V-V-T-F-F-V-S-L-F-I-F-G-F-L-S-N-D-P-G-R-N-P-G-T-K-D-F"} +{"text": "### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-I-S-T-L-G-I-I-F-F-G-I-F-F-R-E-P-P-R-I-V-K"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-P-A-L-V-A-T-V-F-V-S-C-L-V-L-S-I-T-G-Y-S-L-Y-I-G-F-G-P-P-S-K-E-L-R-D-P-F-D-E-H-E-D"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-T-G-S-T-S-K-A-K-A-D-E-S-T-S-K-I-T-P-L-G-T-A-L-K-P-L-N-S-E-Y-G-K-V-A-P-G-W-G-T-T-P-V-M-G-L-F-M-A-L-F-A-V-F-L-L-I-I-L-E-I-Y-N-S-S-L-I-L-D-D-V-G-V-S-W-Y-S-L-G-K"} +{"text": "### FUNCTION Controls the interaction of photosystem II cores with the light-harvesting antenna ### SEQUENCE -M-T-F-I-F-Q-L-A-L-F-A-L-V-A-L-S-F-L-L-V-V-G-V-P-V-A-F-A-A-P-E-G-W-N-V-T-K-G-Y-V-F-Q-G-V-S-A-W-F-A-L-V-F-T-V-G-V-L-N-S-L-V-A"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-V-K-R-G-Y-V-A-R-K-R-R-N-K-I-L-R-A-N-R-S-F-R-G-T-H-S-K-L-F-R-I-A-N-Q-Q-H-M-K-A-L-R-Y-S-Y-R-D-R-A-C-K-K-R-D-F-R-H-L-W-I-T-R-I-N-A-V-V-R-S-Y-G-L-N-Y-S-R-F-M-H-Q-L-R-L-G-N-M-V-L-N-R-K-V-L-S-Q-L-A-S-L-D-P-A-S-F-N-R-L-I-R-A-T"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-K-P-N-P-N-K-Q-T-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-I-L-F-S-S-Y-I-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-N-T-G-T-T-G-R-V-P-L-W-F-V-G-M-I-V-G-L-A-A-L-G-L-L-G-I-F-F-Y-G-S-Y-T-G-L-G-S-S-L"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-D-L-T-L-V-G-Q-L-I-S-L-F-A-V-V-A-A-G-P-L-V-I-V-F-L-S-A-R-R-G-A-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-T-L-P-I-L-L-A-T-L-P-E-A-Y-L-P-F-R-P-L-V-D-V-L-P-S-I-P-V-L-F-L-L-L-A-F-V-W-Q-A-A-V-S-F-R"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-V-E-A-L-L-S-G-I-V-L-G-L-I-P-V-T-L-A-G-L-F-V-T-A-Y-L-Q-Y-R-R-G-D-Q-L-N-L"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex ### SEQUENCE -M-F-T-V-I-S-Y-F-G-F-L-L-V-A-L-A-F-T-L-V-T-Y-L-G-L-R-A-I-Q-L-I"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-D-T-T-N-L-V-R-R-D-I-V-I-G-S-R-R-V-S-N-Y-W-W-A-S-V-L-L-L-G-G-S-S-F-L-V-V-G-L-S-S-R-L-G-F-D-L-V-P-F-L-P-A-G-D-I-I-F-I-P-Q-G-L-V-M-C-F-Y-G-L-V-G-L-V-V-S-T-Y-L-W-L-T-I-L-W-S-V-G-G-G-Y-N-E-F-N-K-Q-E-G-V-M-R-I-F-R-W-G-F-P-G-R-D-R-R-I-Q-L-T-C-P-L-Q-D-I-E-A-I-R-V-E-L-Q-E-G-M-N-P-R-R-T-I-Y-V-R-L-K-G-K-R-E-V-P-L-T-R-I-G-Q-P-L-T-L-A-E-I-E-K-Q-A-A-E-L-A-G-F-L-Q-V-S-L-E-G-F"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-N-T-A-V-K-R-S-I-S-S-D-P-V-Y-N-S-Q-L-I-H-M-M-I-S-H-I-L-K-E-G-K-K-A-L-A-Y-R-L-M-Y-D-A-M-K-R-I-E-K-T-T-Q-Q-D-P-I-L-V-V-E-R-A-V-R-N-A-T-P-T-I-E-V-K-A-R-R-M-G-G-S-I-Y-Q-V-P-L-E-V-K-P-E-R-G-T-A-L-A-L-R-W-I-L-L-A-A-R-N-R-T-G-R-D-M-V-A-K-L-S-N-E-L-M-D-A-S-N-R-I-G-N-A-V-R-K-R-D-E-M-H-R-M-A-E-A-N-K-A-F-A-H-I-R-V"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-I-Q-Q-L-V-R-A-Q-R-K-R-I-V-K-K-T-K-S-P-A-L-C-A-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-S-S-G-F-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-T-A-G-V-K-E-R-K-Q-S-R-S-K-Y-G-V-K-R-V-T-K-K"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-K-D-F-T-T-Y-L-S-T-A-P-V-L-A-A-V-W-F-G-F-L-A-G-L-L-I-E-I-N-R-F-F-P-D-A-L-S-F-S-F-V"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-A-D-I-V-S-A-G-W-A-F-L-M-V-S-F-T-F-S-L-S-L-V-V-W-G-R-S-G-L"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-Q-R-N-D-N-F-I-D-K-T-F-T-V-V-A-D-I-L-L-K-V-L-P-T-T-R-R-E-K-E-A-F-T-Y-Y-R-D-G-M-S-A-Q-A-E-G-E-Y-A-E-A-L-Q-N-Y-Y-E-A-M-R-L-E-V-D-A-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-E-H-A-K-A-L-E-Y-Y-Y-Q-A-L-E-R-N-P-Y-L-P-Q-A-L-N-N-I-A-V-I-Y-H-Y-R-G-E-Q-A-I-E-S-G-N-S-R-I-S-N-L-L-F-D-K-A-A-D-Y-W-K-E-A-I-R-L-A-P-T-N-Y-I-E-A-Q-N-W-L-K-I-T-N-R-L-E-E-A-I"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-V-T-S-F-L-P-S-L-F-V-P-L-V-G-L-V-F-P-A-V-A-M-A-S-L-F-L-Y-I-E-K-D-E-I-A"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-F-H-F-L-A-L-T-P-L-A-H-S-E-G-F-G-L-N-T-N-I-L-E-T-N-I-L-N-L-A-A-V-F-A-L-L-A-Y-V-G-T-D-F-V-S-S-L-L-K-T-R-K-E-S-I-L-K-S-L-R-D-A-D-E-R-Y-Q-D-A-V-N-Q-L-K-Q-A-L-Q-E-L-E-T-A-R-T-N-A-A-E-I-R-R-Q-S-E-I-N-A-E-A-I-R-Q-R-L-E-L-L-T-Q-E-E-M-A-R-L-E-E-A-K-E-T-I-I-K-L-E-E-E-K-A-V-A-E-V-C-T-K-V-I-S-M-A-L-V-R-A-E-K-K-I-I-S-S-M-D-E-A-M-H-R-R-V-M-D-M-Y-L-N-L-L-R-E-V-Y"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-I-D-L-V-K-R-P-V-I-T-E-K-A-T-R-I-L-E-K-N-Q-Y-T-F-D-V-E-L-S-L-T-K-P-K-I-K-A-L-I-E-K-A-F-K-V-E-V-V-S-V-N-T-H-R-P-P-R-R-K-R-R-L-G-T-T-Q-G-Y-L-P-R-Y-K-R-A-I-I-T-L-K-R-G-F-M-I-P-L-T-P-F"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-V-A-N-H-L-L-R-K-I-E-K-M-N-G-K-G-E-K-H-V-I-T-T-W-S-R-A-S-T-I-I-P-I-M-I-G-H-T-I-A-I-H-N-G-K-S-H-L-P-I-F-I-N-D-R-M-I-G-H-K-L-G-E-F-V-L-T-R-N-Y-R-G-H-G-K-T-D-K-K-A-R-R"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-P-Q-T-I-L-Q-V-A-D-N-S-G-A-R-Q-L-M-C-I-R-V-L-G-G-R-K-R-Y-A-S-I-G-D-V-I-I-A-V-V-K-D-A-I-P-N-M-P-V-K-K-S-D-V-V-R-A-V-V-V-R-T-S-K-P-V-R-R-D-T-G-M-L-I-R-F-D-D-N-A-A-V-I-V-N-Q-E-G-N-P-R-G-T-R-V-F-G-P-V-A-R-E-L-R-D-R-Q-F-M-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION Binds 5S rRNA, forms part of the central protuberance of the 50S subunit ### SEQUENCE -M-A-Q-R-L-K-T-F-Y-L-N-S-V-V-P-K-L-R-Q-Q-F-H-H-R-N-I-H-E-V-P-S-I-K-K-I-V-I-N-R-G-L-G-D-A-S-Q-N-A-K-L-L-D-G-S-L-Q-E-L-T-T-I-A-G-Q-R-G-V-I-T-R-S-K-Q-A-I-A-A-F-K-I-R-Q-D-M-P-V-G-I-S-V-T-L-R-G-E-R-M-Y-A-F-L-D-R-L-I-N-L-A-L-P-R-I-R-D-F-Q-G-M-S-T-K-S-F-D-G-Q-G-N-Y-S-L-G-L-N-E-Q-L-M-F-P-E-I-N-Y-D-A-I-D-Q-M-R-G-M-D-I-S-I-I-T-S-A-T-E-D-R-E-G-F-A-L-L-Q-A-L-G-M-P-F-R-T-A-T-I-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-I-Q-D-T-I-A-D-M-L-T-R-I-R-N-A-N-A-M-R-I-Y-T-V-C-M-P-M-T-S-V-A-R-E-I-A-V-I-L-E-T-E-G-W-I-D-S-W-K-E-A-S-V-N-S-L-I-L-R-L-K-Y-R-G-A-K-Q-Q-P-I-L-T-G-L-R-R-V-S-R-S-G-C-R-V-Y-V-S-A-K-E-V-P-K-V-L-G-G-M-G-T-A-I-I-S-T-S-K-G-I-M-T-D-R-E-A-R-N-H-R-L-G-G-E-V-I-C-L-I-W"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-N-K-Q-G-L-F-Q-M-E-G-L-V-I-E-S-L-P-N-A-M-F-R-V-R-L-Q-N-G-F-V-I-L-A-H-I-S-G-K-I-R-R-N-Y-I-R-I-I-V-G-D-R-V-L-C-E-L-T-P-Y-D-L-T-K-G-R-I-V-Y-R-Q-R-S-T-P-R-P"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-T-I-T-N-Q-I-I-E-Q-L-K-S-M-T-L-L-E-A-A-E-L-V-S-Q-I-E-E-T-F-G-V-D-A-S-A-P-A-A-G-A-V-M-V-A-A-A-A-P-S-A-P-V-V-E-E-Q-T-E-F-T-V-M-I-N-D-V-P-S-A-K-R-I-A-V-I-K-V-V-R-A-L-T-G-L-G-L-K-E-A-K-D-M-I-E-S-V-P-K-A-I-K-E-G-I-G-K-D-E-A-Q-Q-I-K-Q-Q-L-E-E-A-G-A-T-V-T-V-K"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-S-V-T-K-K-P-D-L-T-D-P-V-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-M-F-P-V-V-I-L-G-T-L-S-C-I-T-G-L-A-V-L-D-P-A-A-I-G-E-P-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-F-P-V-F-Q-L-L-R-T-V-P-N-K-L-L-G-V-L-L-M-A-A-V-P-A-G-L-L-T-V-P-F-I-E-S-I-N-K-F-Q-N-P-F-R-R-P-V-A-T-T-V-F-L-I-G-T-V-V-A-I-W-L-G-I-G-A-T-L-P-I-D-I-S-L-T-L-G-L-F"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-L-Q-V-R-I-L-T-P-E-Q-V-F-L-N-V-S-A-D-E-I-I-L-P-T-N-T-G-Q-M-G-V-L-T-N-H-T-P-L-I-T-A-I-D-I-G-P-M-L-V-R-S-E-S-T-W-Q-S-M-A-L-L-G-G-L-A-L-V-K-D-N-Q-V-I-I-L-V-N-E-A-E-L-G-S-D-I-N-A-E-E-A-E-T-T-F-L-A-A-K-E-A-L-A-N-S-K-T-R-K-D-Q-I-E-N-N-L-A-F-K-R-A-R-V-R-Y-Q-V-A-T-L-V-K"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-G-L-I-A-T-A-L-F-I-I-I-P-T-S-F-L-L-I-L-Y-V-K-T-A-S-Q-Q-N"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-K-K-S-M-I-E-R-E-S-K-R-A-A-L-V-A-K-Y-A-T-R-R-Q-A-L-K-A-A-I-Q-K-T-K-S-F-D-E-R-L-V-L-Q-H-Q-L-Q-D-L-P-V-N-S-V-P-C-R-L-H-N-R-C-T-I-T-G-R-P-K-G-Y-Y-R-D-F-G-L-S-R-H-E-L-R-A-M-A-H-G-C-L-L-P-G-V-T-K-A-S-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-K-K-S-V-I-Q-R-N-I-N-R-L-K-L-I-N-K-Y-S-A-Q-R-E-A-I-K-N-E-I-K-R-T-S-K-V-E-K-K-I-S-L-Y-S-N-I-S-R-L-P-R-D-S-S-K-V-R-L-R-S-R-C-W-V-T-G-R-G-R-S-V-Y-K-N-F-G-L-S-R-H-M-F-R-F-M-A-S-N-G-L-L-P-G-V-V-K-S-S-W"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-V-E-V-L-L-T-G-I-V-L-G-S-I-F-I-T-L-L-G-L-L-A-A-A-K-L-Q-Y-N-R-K-K-T-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-I-I-N-Q-L-P-E-T-Y-N-I-F-A-P-I-I-D-I-M-P-V-I-P-I-L-F-L-L-L-A-F-V-W-Q-A-A-V-G-F-R"} +{"text": "### FUNCTION PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I reaction center ### SEQUENCE -M-Q-Q-S-L-N-L-K-M-P-S-P-E-F-Y-G-N-T-G-G-W-L-R-S-S-D-I-E-E-K-Y-A-I-T-W-S-S-K-N-E-D-I-F-E-I-P-T-G-G-V-A-K-M-K-A-G-D-N-L-L-Y-L-A-K-K-E-Q-C-L-A-L-G-N-Q-L-K-I-K-F-K-I-L-N-F-K-I-Y-R-I-F-P-N-G-E-A-Q-F-L-H-P-K-D-G-V-F-P-E-K-V-N-E-G-R-K-P-I-G-K-I-D-H-N-I-G-K-N-L-N-P-A-E-V-K-F-T-H-K-T-I-F"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-S-Q-E-I-V-T-V-S-L-I-I-S-I-L-V-L-S-G-L-T-M-G-F-I-L-L-K-I-Q-K"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-N-I-S-L-V-D-L-T-W-A-C-L-M-V-S-F-T-V-S-L-A-L-V-V-W-A-R-N-G-F"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-V-K-R-G-N-V-A-R-K-R-R-K-K-I-L-K-L-A-S-G-F-K-G-A-H-S-K-L-F-R-V-A-N-Q-Q-V-N-K-S-L-R-Y-S-Y-V-G-R-K-L-K-K-R-R-F-R-R-L-W-I-L-R-L-N-A-A-S-R-E-E-G-L-N-Y-S-K-L-V-N-S-L-K-L-L-R-I-Q-L-N-R-K-S-L-S-Q-L-A-M-I-D-N-D-A-F-K-R-L-V-A-S-S-R-V"} +{"text": "### FUNCTION Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex Allophycocyanin has a maximum absorption at approximately 650 nanometers ### SEQUENCE -M-S-I-V-T-K-S-I-V-N-A-D-A-E-A-R-Y-L-S-P-G-E-L-D-R-I-K-S-F-V-M-S-G-Q-R-R-L-R-I-A-Q-I-L-T-D-N-R-E-R-I-V-K-Q-A-G-Q-Q-L-F-Q-K-R-P-D-I-V-S-P-G-G-N-A-Y-G-E-E-M-T-A-T-C-L-R-D-L-D-Y-Y-L-R-L-I-T-Y-S-V-V-A-G-D-V-I-P-I-E-E-I-G-L-V-G-V-R-E-M-Y-N-S-L-G-T-P-L-S-G-V-A-E-G-I-R-S-M-K-S-V-V-S-G-L-L-A-G-D-D-A-A-E-A-S-F-Y-F-D-Y-A-I-G-A-M-Q"} +{"text": "### FUNCTION Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex Allophycocyanin has a maximum absorption at approximately 650 nanometers ### SEQUENCE -M-Q-D-A-I-T-A-V-I-N-A-A-D-V-Q-G-K-Y-L-D-N-N-S-I-E-K-L-R-S-Y-F-Q-T-G-E-L-R-V-R-A-A-A-S-I-S-A-N-A-A-G-I-I-K-E-A-V-A-K-S-L-L-Y-S-D-I-T-R-P-G-G-N-M-Y-T-T-R-R-Y-A-A-C-I-R-D-L-D-Y-Y-L-R-Y-A-T-Y-S-M-L-A-G-D-P-S-I-L-D-E-R-V-L-N-G-L-K-E-T-Y-N-S-L-G-V-P-I-G-A-T-I-Q-S-I-Q-A-M-K-E-V-T-A-S-L-V-G-P-D-A-G-Q-E-M-G-V-Y-F-D-Y-I-C-S-G-L-S"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-A-K-I-I-S-S-E-L-P-D-L-I-L-S-S-V-I-T-D-K-T-I-K-L-L-E-T-K-N-Y-T-F-L-A-P-K-E-V-S-K-I-A-F-K-R-A-I-E-D-M-F-K-V-K-V-N-S-I-N-S-L-N-L-P-N-K-K-K-R-V-G-R-Y-K-T-G-S-L-P-L-Y-K-K-M-I-V-K-L-D-S-K-D-T-I-D-L-F-L-D-R"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-I-K-K-G-P-Y-V-H-F-K-L-L-K-N-T-N-N-L-N-L-S-N-S-K-R-V-I-K-T-W-S-R-S-S-V-I-L-P-S-M-V-G-H-T-I-A-V-H-N-G-K-I-H-V-P-I-F-I-S-D-Q-M-V-G-H-K-L-G-E-F-A-F-T-R-S-F-R-S-H-A-K-I-D-K-K-I-R-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-A-K-E-I-I-G-I-V-I-T-K-S-L-D-K-T-A-I-V-K-T-Q-S-K-S-S-H-E-R-Y-V-K-I-I-K-K-V-K-K-Y-T-V-H-D-R-E-N-I-S-R-V-G-D-K-V-I-I-L-Q-T-R-P-L-S-K-T-K-R-W-V-I-K-S-I-L"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-S-V-H-T-R-L-K-V-I-D-N-S-G-G-K-E-I-M-C-I-R-V-L-G-T-N-R-K-Y-A-T-L-G-D-V-I-I-G-V-V-K-N-A-V-P-N-M-P-V-K-K-S-D-V-V-R-A-V-V-V-R-I-K-K-T-I-N-R-K-N-F-F-S-V-R-F-D-D-N-A-A-V-I-I-G-S-D-G-N-P-K-G-T-R-I-F-G-P-V-A-R-E-L-R-D-K-N-F-S-K-I-A-S-L-A-Q-E-V-V"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-I-N-V-R-V-I-N-K-K-R-R-I-Q-K-Y-K-V-S-V-K-S-G-D-T-I-K-V-I-S-G-K-Y-K-N-I-V-A-K-V-L-R-V-L-K-Y-S-N-E-I-I-V-K-G-V-N-I-K-I-K-H-I-K-P-V-R-D-N-E-M-G-S-L-K-S-L-E-F-P-I-N-I-S-K-V-V-L-L-E-S-R-K-K-E"} +{"text": "### FUNCTION Binds 5S rRNA, forms part of the central protuberance of the 50S subunit ### SEQUENCE -M-S-G-G-N-L-Q-H-L-Y-F-N-K-I-R-V-E-L-Q-K-Q-F-E-Y-T-N-V-H-Q-I-P-K-L-T-K-I-T-L-N-R-G-L-G-T-L-Y-Q-Q-S-P-K-V-F-E-S-S-V-S-D-L-M-L-I-T-G-Q-K-P-R-F-N-K-S-K-K-S-I-A-G-F-K-L-R-E-G-T-V-V-G-L-S-V-T-L-R-R-K-K-M-Y-A-F-L-E-K-L-I-H-F-S-L-P-A-A-R-D-F-R-G-L-S-T-K-N-F-D-G-L-G-N-Y-N-L-G-I-K-E-H-A-I-F-P-E-I-D-F-D-K-I-D-H-S-Y-G-L-N-I-C-I-V-T-T-A-N-N-D-I-E-G-K-A-L-L-K-F-L-G-M-P-F-K-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-N-D-S-I-S-D-M-L-T-R-L-R-N-A-I-C-A-Q-H-K-V-V-Q-V-P-L-T-N-I-N-K-N-I-L-K-V-L-Q-K-E-G-Y-I-K-N-F-E-I-L-F-E-R-K-S-G-Y-L-L-V-S-L-K-Y-N-S-L-N-Q-D-K-P-C-L-S-V-L-K-K-I-S-R-P-G-L-R-M-Y-V-R-T-K-K-I-P-K-V-L-G-G-T-G-I-A-I-I-S-T-S-K-G-V-M-T-G-S-I-A-R-N-L-G-I-G-G-E-I-L-C-Y-I-W"} +{"text": "### FUNCTION Binds 5S rRNA, forms part of the central protuberance of the 50S subunit ### SEQUENCE -M-I-N-D-I-K-Q-L-H-K-R-Y-R-L-L-V-H-L-S-N-N-H-V-Y-A-Q-I-I-D-D-L-N-N-R-T-V-L-S-V-S-T-L-T-P-Q-V-K-S-K-L-S-I-T-C-N-K-K-A-A-E-L-V-G-E-Y-V-A-Q-Q-A-L-N-F-G-I-R-N-V-V-F-D-R-G-R-K-L-Y-H-G-K-V-E-V-L-A-N-S-A-R-S-F-G-L-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-R-D-T-S-A-N-S-S-G-Q-Q-N-Y-T-W-S-E-R-V-I-Q-I-T-R-V-T-K-V-V-K-G-G-K-K-L-S-F-R-A-I-I-V-I-G-N-N-Q-G-S-V-G-V-G-V-G-K-A-S-D-V-I-G-A-V-K-K-G-V-S-D-C-K-K-Q-I-I-E-F-P-L-T-S-S-S-T-I-S-H-A-V-E-G-R-F-G-A-A-S-V-I-L-K-P-S-V-Q-G-S-G-V-I-A-G-G-A-M-R-T-V-I-E-L-S-G-I-K-N-I-V-A-K-Q-L-G-T-K-N-H-L-N-N-A-K-A-T-I-N-A-L-S-K-L-N-S-K-S-S-Q-L-S-L-M-S-F-S-N"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-A-K-K-N-I-H-P-Q-W-Y-E-E-A-K-F-Y-C-N-G-E-I-V-K-I-I-G-S-T-R-M-E-I-N-A-D-I-W-S-G-N-H-P-F-Y-I-G-T-Q-K-I-V-D-T-E-G-R-I-D-K-F-I-R-K-Y-N-L-N-S-E-N-S-E-S-L"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-I-Q-Q-L-I-R-F-E-R-K-Q-I-V-G-T-S-K-S-A-A-L-E-S-C-P-Q-K-K-G-V-C-T-K-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-I-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-I-R-G-A-L-D-S-T-G-V-K-N-R-L-R-A-R-S-K-Y-G-A-S-K-P-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-Q-K-D-P-Y-K-T-Y-R-L-V-S-D-P-F-Y-E-S-P-L-V-T-L-L-I-M-H-V-L-R-N-G-K-K-S-I-S-Q-R-I-V-Y-S-A-I-E-N-I-A-M-K-V-K-E-D-P-L-E-I-I-E-R-A-I-K-N-V-I-P-A-V-E-I-R-S-R-R-I-G-G-S-T-Y-Q-V-P-T-E-V-R-V-H-R-G-I-S-L-S-I-R-W-V-I-K-F-A-K-I-R-P-G-K-S-M-S-L-K-L-A-N-E-L-L-D-A-S-K-N-L-G-N-S-I-R-K-K-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-Y-R-Y"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-V-R-P-L-N-D-F-H-E-A-K-V-R-I-K-L-S-S-Y-S-A-S-L-L-N-L-S-C-N-N-V-L-Q-S-I-K-E-S-N-T-S-V-K-G-P-V-F-L-P-T-R-R-R-V-Y-C-V-L-R-S-P-H-V-N-K-D-S-R-E-H-F-E-I-R-S-H-F-R-I-I-D-I-S-S-C-S-S-E-T-I-E-M-L-M-R-L-D-L-P-T-G-V-N-I-E-I-K-T"} +{"text": "### FUNCTION Allophycocyanin is a photosynthetic bile pigment-protein complex with maximum absorption at approximately 650 nanometers ### SEQUENCE -M-S-F-V-S-K-T-I-I-E-A-D-H-E-L-R-Y-L-N-G-A-E-L-E-I-L-R-A-Y-L-N-S-S-E-K-R-I-K-V-I-K-T-L-R-D-R-E-K-E-I-I-S-K-A-S-R-K-L-F-Q-I-H-P-D-Y-I-G-P-G-G-N-A-S-G-S-R-Q-R-A-L-C-L-R-D-Y-G-W-Y-L-R-L-I-T-Y-S-I-I-A-G-D-K-N-P-V-E-R-I-G-L-L-G-V-R-D-M-Y-N-S-L-G-V-P-L-I-G-M-V-D-S-I-Q-C-L-K-D-A-A-L-A-E-L-K-S-E-E-E-V-K-L-A-E-P-Y-F-D-F-V-I-Q-N-M-A-Q"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-D-K-N-L-L-K-Y-I-Y-T-V-P-V-I-S-T-L-W-L-L-L-T-A-G-I-L-I-E-I-N-R-F-Y-P-D-A-L-F-Y-A-F"} +{"text": "### FUNCTION Probably participates in efficiency of electron transfer from plastocyanin to P700 This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI ### SEQUENCE -M-K-S-K-V-L-Q-R-F-V-L-C-I-T-A-S-L-L-F-W-N-L-N-I-A-T-H-A-S-T-L-T-P-C-E-N-S-A-Q-F-Q-A-R-L-N-N-N-I-K-K-L-E-N-K-L-T-Y-Y-K-Q-N-S-Q-E-Y-T-S-I-K-Q-Q-I-E-K-T-K-I-R-F-D-K-Y-A-K-S-S-L-L-C-G-E-D-G-L-P-H-L-I-T-D-G-D-W-Q-H-S-G-E-F-F-I-P-S-V-L-F-I-Y-I-A-G-W-I-G-W-A-G-K-G-Y-L-Q-Y-S-K-T-L-T-K-P-N-E-N-E-I-I-I-D-L-P-R-A-L-K-Y-M-F-S-G-F-A-W-P-I-L-A-L-K-E-F-K-N-G-S-L-L-A-S-N-D-E-I-T-T-S-P-R"} +{"text": "### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-L-N-W-Q-V-I-V-Q-L-V-F-L-A-L-I-I-T-T-G-P-V-I-I-V-Y-L-S-T-R-E-R-N-L-L"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-L-G-G-E-L-L-K-Y-K-S-S-K-E-S-H-I-L-I-N-E-N-I-N-F-P-C-V-R-V-V-D-V-T-G-K-Q-L-G-I-L-D-T-R-Q-A-V-E-Y-A-K-N-Q-G-V-D-L-V-L-V-N-E-I-S-D-P-P-V-C-K-L-I-D-Y-G-K-H-K-F-I-V-E-K-R-V-K-E-G-R-K-K-Q-S-G-A-L-V-K-E-V-K-M-T-Y-K-I-N-E-H-D-Y-E-T-R-L-N-Q-A-F-K-F-L-K-S-G-N-K-V-K-V-T-L-T-F-K-G-R-E-I-Q-H-L-S-L-G-T-M-L-L-N-R-L-M-T-D-L-Q-Q-I-A-E-V-K-R-S-P-Y-Q-D-G-K-T-M-I-L-I-L-T-P-K-I-V-D-P-Q"} +{"text": "### FUNCTION Probably a ribosomal protein or a ribosome-associated protein ### SEQUENCE -M-K-Q-Y-K-I-K-V-L-W-L-R-N-N-I-A-I-A-V-D-R-L-I-G-D-S-L-F-P-M-T-Y-Y-Y-F-W-P-R-T-D-A-W-E-Q-L-K-I-E-L-D-S-Q-P-G-L-F-A-K-D-K-V-V-I-L-N-Q-V-T-R-I-I-D-Y-W-Q-E-N-K-K-S-V-F-P-N-L-S-E-L-Q-S-H-F-P-D-L-I-C-S-G-C-Y"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-T-I-I-K-K-P-D-L-N-N-A-L-L-R-A-K-L-A-K-G-M-G-H-S-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-T-F-P-I-V-I-L-G-T-I-T-C-C-V-G-L-A-V-L-E-P-S-S-L-G-E-P-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-L-Y-P-T-F-N-M-L-R-I-I-P-N-K-L-F-G-V-I-S-I-S-L-V-P-V-G-L-G-I-V-P-F-V-E-N-I-N-K-F-Q-N-P-F-R-R-P-I-A-T-S-V-F-I-F-G-T-V-T-T-V-W-L-G-I-G-A-T-M-S-I-D-K-A-L-T-L-G-I-F-F"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-D-K-I-D-E-I-V-E-K-I-K-L-L-S-L-L-E-A-S-E-L-V-K-R-I-E-D-T-F-Q-V-N-V-S-N-I-Q-P-V-T-G-L-S-S-N-L-T-T-T-Q-Q-T-P-E-S-A-E-V-K-E-K-W-D-V-I-L-E-N-V-P-A-D-K-K-I-A-I-L-K-V-V-R-S-I-T-G-L-G-L-K-E-A-K-E-F-V-E-S-V-P-K-I-I-K-Q-S-I-S-Q-A-D-A-E-H-I-K-Q-Q-I-E-D-A-G-A-S-V-V-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-I-K-K-I-I-T-T-V-K-L-A-L-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-M-F-V-K-E-Y-N-A-R-T-E-E-Q-K-G-S-I-I-P-A-E-I-Q-I-Y-E-D-K-S-F-T-F-I-L-K-T-P-P-A-S-I-L-L-K-Q-A-T-G-I-E-K-A-T-K-A-P-R-R-E-Q-V-G-S-I-S-Y-K-E-I-Q-N-I-A-K-I-K-I-N-E-L-N-T-K-D-L-S-K-A-I-K-I-I-E-G-T-A-K-N-M-G-I-S-V-E-T"} +{"text": "### FUNCTION Possible role in chlorophyll and/or carotenoid binding ### SEQUENCE -M-P-K-Y-G-F-H-Q-S-T-E-L-I-N-G-R-L-A-M-L-A-F-I-L-S-L-F-I-E-F-I-T-E-Q-K-I-L-H-F-L-K-F-L"} +{"text": "### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-K-K-I-K-R-D-K-I-V-G-A-G-K-I-S-N-Y-L-L-L-I-I-M-L-G-G-G-I-S-F-F-I-V-G-F-L-S-Y-F-K-A-F-E-H-I-A-L-F-S-R-F-V-N-S-D-I-R-F-I-P-Q-G-I-T-M-I-F-Y-G-T-M-A-I-C-L-S-I-Y-I-Y-F-S-I-Y-Y-D-I-G-A-G-Y-N-E-F-N-L-I-S-K-K-V-V-V-F-R-K-G-F-P-G-K-N-R-L-I-K-F-V-L-P-I-P-H-L-K-S-V-K-V-M-A-R-G-G-I-N-P-K-Y-E-V-F-L-Y-T-K-N-L-S-R-I-P-I-G-Q-V-F-K-L-S-K-L-E-Y-Q-A-S-E-I-A-T-F-L-G-L-A-F-E-Q-Y-N-L"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-S-G-I-N-P-N-K-Q-P-V-E-L-N-R-T-S-L-F-W-G-L-L-L-I-F-V-L-A-V-L-F-S-S-Y-F-F-N"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-N-S-T-G-R-I-P-L-W-L-V-V-T-F-G-G-I-V-V-L-T-V-L-G-I-F-I-Y-G-S-Y-S-G-L-G-S-S-L"} +{"text": "### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-A-I-S-Y-L-P-A-I-L-V-P-V-I-G-L-V-M-P-I-F-C-I-V-F-L-F-L-Y-I-E-K-E-S-L-N"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-I-L-L-L-T-N-S-K-I-I-Y-P-Y-S-E-A-L-F-S-I-A-K-D-Q-E-K-F-E-V-I-K-N-D-M-E-L-F-V-T-F-T-K-N-L-N-G-F-K-K-F-L-E-T-P-L-I-N-K-N-K-K-I-K-V-V-K-D-V-F-S-K-I-L-N-S-T-T-L-N-F-I-S-I-L-I-N-K-N-R-I-M-F-V-S-N-I-S-E-K-Y-N-Q-L-V-L-K-D-K-S-V-K-L-V-K-I-A-C-A-R-Q-L-S-E-K-Q-A-Q-A-L-S-E-V-L-K-H-K-F-K-C-L-S-V-K-L-I-F-N-I-E-P-E-L-I-A-G-F-K-I-F-I-E-S-Q-V-I-D-V-S-L-Q-G-E-L-K-E-F-E-W-Y-L-T-K"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-R-S-Q-S-L-N-F-V-A-S-N-T-T-S-D-F-I-S-N-L-L-E-S-N-V-I-N-I-I-I-L-I-S-L-L-I-Y-L-G-K-R-T-I-V-T-N-L-N-D-R-K-L-N-I-Q-C-S-I-L-E-A-E-K-K-L-S-Q-A-Q-L-R-L-A-E-A-E-K-K-I-T-E-S-E-E-I-I-S-I-L-K-H-E-A-K-I-A-A-N-K-I-K-E-L-I-V-N-N-A-K-R-K-I-D-K-I-I-L-D-G-K-T-I-I-A-N-T-E-I-E-I-M-N-Q-I-K-N-R-I-I-S-T-A-I-D-K-T-K-I-K-L-T-K-N-L-Q-A-E-T-I-E-R-I-T-D-N-K-I-T-F-L-N-N-N-L"} +{"text": "### FUNCTION P-II indirectly controls the transcription of the glutamine synthetase gene ### SEQUENCE -M-F-S-K-L-E-A-I-I-R-P-F-K-L-E-E-V-K-V-R-L-M-T-F-G-V-P-G-I-T-V-T-N-V-M-G-C-G-K-Q-I-G-G-I-E-R-S-K-G-V-E-Y-D-S-E-L-I-E-K-V-K-I-E-I-V-V-M-N-E-H-I-D-E-L-I-E-I-I-I-N-A-V-W-T-G-E-I-G-D-G-K-I-F-V-S-P-V-S-S-V-I-R-I-R-T-Q-D-K-D-L-D-A-I"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-L-T-V-K-V-I-T-P-D-R-V-V-W-K-K-T-V-E-E-I-I-L-P-S-S-T-G-Q-L-G-I-L-M-N-H-A-P-L-L-T-A-L-D-I-G-V-M-R-A-R-M-V-N-T-W-V-P-L-V-L-L-G-G-F-A-Q-I-D-N-N-L-V-T-I-I-V-S-D-A-E-E-V-K-A-I-D-E-E-E-A-N-K-L-L-A-A-S-L-A-N-M-E-K-A-Q-S-N-R-E-K-I-E-S-M-Q-N-L-R-R-A-R-A-R-M-Q-A-I-L-S-L-K"} +{"text": "### FUNCTION Essential for the assembly of the photosystem I complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-Q-K-N-D-N-F-I-D-K-T-F-S-I-I-A-D-L-I-V-K-I-L-P-T-N-K-E-S-K-E-A-F-Y-Y-Y-K-D-G-M-A-A-Q-S-E-G-E-Y-A-E-A-L-A-C-Y-Y-Q-A-L-K-I-E-K-D-P-M-D-K-S-F-I-L-Y-N-I-G-L-I-Q-A-S-N-G-Q-H-A-R-A-L-E-Y-Y-H-E-S-L-K-F-N-P-N-L-V-Q-A-L-N-N-I-A-V-I-Y-H-Y-Y-G-N-K-L-F-E-Q-S-K-L-Q-E-A-K-L-M-F-D-K-A-S-N-Y-W-R-K-A-I-K-L-A-P-Y-N-Y-I-E-A-Q-N-W-L-K-I-T-G-R-I-T-E-D-I-M-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit ### SEQUENCE -M-S-R-R-G-T-V-E-E-K-T-A-K-S-D-P-I-Y-R-N-R-L-V-N-M-L-V-N-R-I-L-K-H-G-K-K-S-L-A-Y-Q-I-L-Y-R-A-V-K-K-I-Q-Q-K-T-E-T-N-P-L-S-V-L-R-Q-A-I-R-G-V-T-P-D-I-A-V-K-A-R-R-V-G-G-S-T-H-Q-V-P-I-E-I-G-S-T-Q-G-K-A-L-A-I-R-W-L-L-G-A-A-R-K-R-P-G-R-N-M-A-F-K-L-S-S-E-L-V-D-A-A-K-G-S-G-D-A-I-R-K-K-E-E-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-L-T-N-N-Q-L-L-K-H-S-R-I-K-K-K-K-Q-S-Y-N-F-Y-T-K-P-Q-I-K-G-L-C-I-K-V-F-T-R-T-P-K-K-P-N-S-A-L-R-K-I-A-K-I-K-L-K-N-K-K-E-I-L-A-Y-I-P-G-E-G-H-A-L-Q-D-H-N-F-V-L-I-K-K-G-R-V-Q-D-L-P-G-I-K-Y-K-V-I-R-G-V-L-D-T-I-G-V-L-N-R-K-S-S-R-S-K-Y-G-T-K-K-I-I"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -L-E-N-R-V-A-E-K-Q-K-L-F-Q-E-D-N-G-L-P-V-H-L-K-G-G-A-T-D-N"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -F-E-N-K-V-P-E-K-Q-K-L-F-Q-E-D-N-G-I-P-V-V-L-K-G-G-V-A-D-A"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -F-E-N-K-V-P-E-K-Q-K-L-F-Q-E-D-N-G-I-P-V-H-L-K-G"} +{"text": "### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -F-E-N-K-V-A-E-K-Q-K-L-F-Q-A-D-N-G-L-P-V-X-L-K"} +{"text": "### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-A-R-F-V-V-V-A-L-L-V-L-L-S-V-S-D-L-E-A-I-Q-H-P-P-K-I-Q-V-Y-S-R-Y-P-A-D-N-G-K-P-N-F-L-N-C-Y-V-S-G-F-H-P-S-D-I-E-V-D-L-L-K-N-G-K-K-I-E-K-V-E-H-S-D-L-S-F-S-K-D-W-S-F-Y-L-L-Y-Y-T-E-F-T-P-N-E-K-D-E-Y-A-C-R-V-S-H-V-T-F-L-T-P-K-T-V-K-W-D-R-N-M"} +{"text": "### FUNCTION Binds and deliver cytosolic copper to the copper ATPase proteins May be important in cellular antioxidant defense ### SEQUENCE -M-P-K-H-E-F-S-V-D-M-T-C-E-G-C-S-N-A-V-S-R-V-L-N-K-L-G-G-V-E-F-D-I-D-L-P-N-K-K-V-C-I-N-S-E-H-S-V-D-I-L-L-E-T-L-E-K-T-G-K-A-V-S-Y-L-G-P-K"} +{"text": "### FUNCTION Affects the rate of fibrils formation May have a primary role in collagen fibrillogenesis ### SEQUENCE -L-D-H-N-N-L-T-R-M-P-G-P-L-P-R-S-L-R-E-L-H-L-D-H-N-Q-I-S-R-V-P-N-N-A-L-E-G-L-E-N-L-T-A-L-Y-L-Q-H-N-E-I-Q-E-V-G-S-S-M-R-G-L-R-S-L-I-L-L-D-L-S-Y-N-H-L-R-K-V-P-D-G-L-P-S-A-L-E-Q-L-Y-L-E-H-N-N-V-Y-S-V-P-D-S-Y-F-R-G-S-P-K-L-L-Y-V-R-L-S-H-N-S-L-T-N-N-G-L-A-S-N-T-F-N-S-S-S-L-L-E-L-D-L-S-Y-N-Q-L-Q-K-I"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-R-H-S-R-S-R-S-R-S-R-Y-R-R-R-R-R-R-R-S-R-H-H-N-R-R-R-T-Y-R-R-S-R-R-H-S-R-R-R-R-G-R-R-R-G-Y-S-R-R-R-Y-S-R-R-R-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-R-H-S-R-S-R-S-R-S-R-Y-R-R-R-R-R-R-R-S-R-H-H-N-R-R-R-T-Y-R-R-S-R-R-H-S-R-R-R-R-R-R-R-R-G-Y-S-R-R-R-Y-S-R-R-G-R-R-R-Y"} +{"text": "### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-R-H-S-R-S-R-S-R-S-R-Y-R-R-R-R-R-R-R-S-R-H-H-N-R-R-R-T-Y-R-R-S-R-R-H-S-I-R-R-R-G-R-R-R-G-Y-S-R-R-R-Y-S-R-R-G-R-R-R-Y"} +{"text": "### FUNCTION Pore-forming ### SEQUENCE -L-L-K-E-T-E-E-G-S-Q-A-P-D-C-G-Y-A-C-Q-P-L-A-V-V-D-L-I-V-D-I-M-F-I-V-D-I-L-I-N-F-R-T-T-Y-V-N-A-N-E-E-V-V-S-H-P-G-R-I-A-V-H-Y-F-K-G-W-F-L-I-D-M-V-A-A-I-P-F-D-L-L-I-F-G-S-G-S-E-E-L-I-G-L-L-K-T-A-R"} +{"text": "### FUNCTION Seems to bind zinc and copper Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia ### SEQUENCE -M-D-P-G-E-C-T-C-M-S-G-G-I-C-I-C-G-D-N-C-K-C-T-T-C-N-C-K-T-C-R-K-S-C-C-P-C-C-P-P-G-C-A-K-C-A-Q-G-C-I-C-K-G-G-S-D-K-C-S-C-C-A"} +{"text": "### FUNCTION Potentiates the contractile activity of bradykinin on the isolated guinea-pig ileum Inhibits the hydrolysis of bradykinin by angiotensin-converting enzyme and also inhibits the conversion of angiotensin I to angiotensin II by kininase II from guinea-pig ileum tissue Also increases the depressor effect of bradykinin on arterial blood pressure in the anaesthetized rat ### SEQUENCE -K-K-D-G-Y-P-V-E-Y-D-R-A-Y"} +{"text": "### FUNCTION Has a vascular smooth muscle contracting activity Causes short-lived contractions of both arterial and venous rabbit vessels ### SEQUENCE -L-A-K-R-A-D-I-C-Q-P-G-K-T-S-Q-R-A-C-E-T"} +{"text": "### FUNCTION Component of the larval cuticle ### SEQUENCE -G-L-I-G-A-P-I-A-A-P-I-A-A-P-L-A-T-S-V-V-S-T-R-T-I-H-A-A-P-V-A-V-A-H-A-A-P-L-A-V-A-H-A-A-P-V-A-V-A-H-A-A-P-L-A-V-A-H-A-A-P-V-A-V-A-H-A-A-P-L-A-V-A-H-A-A-P-A-I-A-Y-G-G-Y-G-S-G-L-I-G-G-A-Y-G-G-G-L-I-G-S-R-S-L-Y-G-G-Y-G-S-G-L-G-I-A-R-S-T-P-G-G-Y-G-S-G-L-I-G-G-A-Y-G-S-G-L-I-G-G-G-L-Y-G-A-R-Y-G-L-G-A-P-A-L-G-H-G-L-I-G-G-A-H-L-Y"} +{"text": "### FUNCTION Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB ### SEQUENCE -M-P-S-T-S-M-I-E-D-R-S-E-I-E-R-R-R-F-E-Y-L-D-H-P-A-D-I-Q-L-H-S-W-G-S-T-M-E-E-A-F-E-A-C-L-V-S-M-F-G-Y-M-T-D-L-A-K-V-D-E-M-Y-E-F-Y-W-K-A-S-G-D-S-L-D-G-L-L-F-Q-F-L-D-E-A-L-N-S-F-H-A-E-P-C-F-V-A-K-R-V-E-I-L-R-F-D-K-K-K-F-E-I-E-F-R-G-W-G-E-S-F-D-T-S-K-H-E-T-E-A-D-I-K-S-P-T-Y-S-N-M-Q-I-N-E-K-P-E-R-C-D-I-Y-V-I-V-D-I"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-D-S-Y-L-D-N-L-V-A-Q-S-K-D-A-S-G-T-A-H-V-D-R-C-C-I-I-G-L-D-G-G-A-A-W-T-T-A-G-H-A-C-A-L-K-L-Q-G-Q-E-G-P-N-I-A-K-C-F-K-S-K-D-F-T-A-F-M-S-G-G-V-R-A-E-G-E-K-Y-Q-F-L-R-E-E-E-G-K-T-V-L-A-K-K-K-G-N-G-A-I-T-L-Q-A-S-K-T-A-I-V-L-G-H-C-P-E-G-G-Q-Q-G-N-T-N-K-A-V-G-V-I-A-D-Y-L-E-S-L-G-M"} +{"text": "### FUNCTION Guanine-nucleotide-releasing protein that acts on members of the sec4/ypt1/rab subfamily ### SEQUENCE -M-T-T-E-Y-L-D-E-E-R-D-L-P-L-P-R-Q-K-K-G-I-D-H-T-Q-T-E-P-I-R-G-F-F-G-V-K-D-M-F-A-F-E-N-V-G-F-T-R-S-S-E-G-K-R-Y-L-V-C-G-E-C-E-Q-G-P-V-G-F-V-D-P-V-T-E-M-N-Y-V-S-P-E-R-L-D-V-L-P-D-V-A-A-A-A-V-E-A-G-K"} +{"text": "### FUNCTION Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome ### SEQUENCE -M-P-S-G-G-Q-R-K-H-T-I-S-N-K-T-R-K-R-P-G-K-D-L-D-Q-I-H-E-D-L-K-P-E-K-A-A-K-L-L-Q-Q-E-I-D-Y-D-L-P-G-N-G-Q-F-Y-C-I-E-C-E-R-H-F-V-D-E-K-T-R-Q-L-H-R-K-T-K-L-H-K-N-R-V-K-T-L-K-E-V-P-Y-T-Q-A-E-A-N-A-A-G-G-S-G-F-F-P-A-I-T-L-K-T-R-V-E-L-P-K-Q-P-E-I-P-I-P-V-V-A-E-T"} +{"text": "### FUNCTION Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions ### SEQUENCE -M-G-R-R-K-S-K-R-K-P-P-P-K-R-K-A-I-E-P-L-D-Q-Q-F-N-C-P-F-C-N-H-E-K-S-C-E-V-K-M-D-R-A-K-N-T-A-M-I-Q-C-T-V-C-L-E-D-F-H-T-T-T-N-V-L-S-E-P-I-D-V-Y-N-D-W-V-D-A-C-E-S-A-N"} +{"text": "### FUNCTION The metallothioneins are involved in the cellular sequestration of toxic metal ions ### SEQUENCE -M-P-S-P-C-N-C-I-E-T-Q-V-C-I-C-G-T-G-C-S-G-E-G-C-R-C-G-D-A-C-K-C-S-S-G-C-G-C-S-G-C-K-V-V-C-K-C-Q-P-G-E-C-A-C-G-K-Q-C-T-G-P-D-T-C-K-C-D-S-S-C-S-C-K"} +{"text": "### FUNCTION FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters ### SEQUENCE -M-A-N-I-A-G-Q-Y-K-L-D-K-S-E-N-F-D-Q-F-L-D-K-L-G-V-G-F-L-V-K-T-A-A-K-T-V-K-P-T-L-E-V-A-V-D-G-D-T-Y-I-F-R-S-L-S-T-F-K-N-T-E-I-K-F-K-L-G-E-E-F-E-E-D-R-A-D-G-K-R-V-K-T-V-I-V-K-D-G-D-N-K-F-V-Q-T-Q-Y-G-D-K-E-V-K-V-V-R-E-F-K-G-D-E-V-E-V-T-A-S-V-D-G-V-T-S-V-R-P-Y-K-R-A"} +{"text": "### FUNCTION The metallothioneins are involved in the cellular sequestration of toxic metal ions and regulation of essential trace elements This isoform binds exclusively copper ### SEQUENCE -M-P-C-G-C-G-T-S-C-K-C-G-S-G-K-C-C-C-G-S-T-C-N-C-T-T-C-P-S-K-Q-S-C-S-C-N-D-G-A-C-G-S-A-C-Q-C-K-T-S-C-C-C-G-A-D-C-K-C-S-P-C-P-M-K"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-L-V-M-A-D-D-S-N-N-G-L-A-N-L-F-S-K-S-R-D-E-M-E-D-P-E-A-S-K-L-E-K-K-D-C-Q-E-K-W-D-F-C-P-A-P-F-F-G-S-R-Y-C-C-F-G-L-F-C-T-L-F-F-C-A"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-F-V-T-A-V-P-H-S-S-N-A-L-E-N-L-Y-L-K-A-R-H-E-M-E-N-P-E-A-S-K-L-N-T-R-D-D-C-E-P-P-G-N-F-C-G-M-I-K-I-G-P-P-C-C-S-G-W-C-F-F-A-C-A"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-F-V-T-A-V-P-H-S-S-N-A-L-E-N-L-Y-L-K-A-H-H-E-M-N-N-P-E-D-S-E-L-N-K-R-C-Y-D-S-G-T-S-C-N-T-G-N-Q-C-C-S-G-W-C-I-F-V-C-L"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-F-V-T-A-V-P-H-S-S-N-A-L-E-N-L-Y-L-K-A-H-H-E-M-N-N-P-E-D-S-E-L-N-K-R-C-Y-D-G-G-T-S-C-D-S-G-I-Q-C-C-S-G-W-C-I-F-V-C-L"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-F-A-T-A-D-D-S-S-N-G-L-E-N-L-F-L-K-A-H-H-E-M-N-P-E-A-S-K-L-N-E-R-C-L-D-A-G-E-I-C-D-F-F-F-P-T-C-C-G-Y-C-I-L-L-F-C-A"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-F-A-T-A-D-D-S-S-N-G-L-E-N-L-F-P-K-A-H-H-E-M-K-N-P-E-A-S-K-L-N-E-R-C-L-D-A-G-E-I-C-D-F-F-F-P-T-C-C-G-Y-C-I-L-L-F-C-A"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-F-V-T-A-I-T-S-N-G-L-E-N-L-F-P-K-A-H-H-E-M-K-N-P-E-A-S-K-L-N-K-R-C-V-P-Y-E-G-P-C-N-W-L-T-Q-N-C-C-D-A-T-C-V-V-F-W-C-L"} +{"text": "### FUNCTION Delta-conotoxins bind to site 6 of voltage-gated sodium channels and inhibit the inactivation process ### SEQUENCE -M-K-L-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-F-A-T-A-D-D-S-G-N-G-L-E-N-L-F-S-N-A-H-H-Q-M-K-N-P-E-A-S-K-L-N-K-R-W-C-K-Q-S-G-E-M-C-N-L-L-D-Q-N-C-C-D-G-Y-C-I-V-F-V-C-T"} +{"text": "### FUNCTION Mu-conotoxins block voltage-gated sodium channels ### SEQUENCE -M-N-L-T-C-M-M-I-V-A-V-L-F-L-T-A-W-T-F-V-M-A-D-D-S-N-N-G-L-A-N-L-F-S-K-S-R-Y-E-M-E-D-P-E-P-S-K-L-E-K-R-K-T-C-Q-R-R-W-D-F-C-P-G-A-L-V-G-V-I-T-C-C-G-G-L-I-C-L-G-V-M-C-I"} +{"text": "### FUNCTION Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding Calcium-binding is required for the activation of calmodulin Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II , and phosphatases ### SEQUENCE -M-A-D-Q-L-T-E-E-Q-I-A-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-T-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-Q-D-M-I-N-E-V-N-A-D-G-N-G-T-I-D-F-P-E-F-L-T-M-M-A-R-K-M-K-D-T-D-S-E-E-E-I-R-E-A-F-R-V-F-D-K-D-G-N-G-Y-I-S-A-A-E-L-R-H-V-M-T-N-L-G-E-K-L-T-D-E-E-V-D-E-M-I-R-E-A-D-I-D-G-D-G-Q-V-N-Y-E-E-F-V-Q-M-M-T-A-K"} +{"text": "### FUNCTION Stimulator of protein export for NES-containing proteins Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA ### SEQUENCE -M-S-M-K-T-T-Q-E-I-N-K-E-D-E-E-L-C-N-E-S-K-K-F-M-D-V-Y-Y-D-V-M-D-R-K-R-E-K-I-G-F-L-Y-T-Q-V-S-N-A-V-W-N-G-N-P-I-N-G-Y-D-S-I-C-E-F-M-K-A-L-P-S-T-Q-H-D-I-Q-S-L-D-A-Q-R-L-P-E-G-V-T-G-D-M-S-G-G-M-L-L-N-V-A-G-A-V-T-V-D-G-D-S-K-R-A-F-T-Q-T-L-L-L-G-V-E-D-G-K-Y-K-V-K-S-D-R-F-R-Y-V-D"} +{"text": "### FUNCTION Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca complex are a number of protein kinases and phosphatases ### SEQUENCE -M-A-D-Q-L-T-E-E-Q-I-A-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-T-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-Q-D-M-I-N-E-V-D-A-D-G-N-G-T-I-D-F-P-E-F-L-T-M-M-A-R-K-M-K-D-T-D-S-E-E-E-I-R-E-A-F-R-V-F-D-K-D-G-N-G-F-I-S-A-A-E-L-R-H-V-M-T-N-L-G-E-K-L-T-D-E-E-V-D-E-M-V-R-E-A-D-I-D-G-D-G-Q-V-N-Y-E-E-F-V-E-M-M-T-S-K"} +{"text": "### FUNCTION May be involved in transcriptional regulation ### SEQUENCE -M-K-S-C-Q-K-M-E-G-K-P-E-N-E-S-E-P-K-H-E-E-E-P-K-P-E-E-K-P-E-E-E-E-K-L-E-E-E-A-K-A-K-G-T-F-R-E-R-L-I-Q-S-L-Q-E-F-K-E-D-I-H-N-R-H-L-S-N-E-D-M-F-R-E-V-D-E-I-D-E-I-R-R-V-R-N-K-L-I-V-M-R-W-K-V-N-R-N-H-P-Y-P-Y-L-M"} +{"text": "### FUNCTION May have a potential role in hypercalcemia of malignancy ### SEQUENCE -M-A-Q-G-Q-R-K-F-Q-A-H-K-P-A-K-S-K-T-A-A-A-A-S-E-K-N-R-G-P-R-K-G-G-R-V-I-A-P-K-K-A-R-V-V-Q-Q-Q-K-L-K-K-N-L-E-V-G-I-R-K-K-I-E-H-D-V-V-M-K-A-S-S-S-L-P-K-K-L-A-L-L-K-A-P-A-K-K-K-G-A-A-A-A-T-S-S-K-T-P-S"} +{"text": "### FUNCTION Plays a role in the maintenance of mitochondrial DNA ### SEQUENCE -M-S-K-V-P-I-N-S-S-K-L-S-C-G-G-P-Y-N-Q-A-V-K-S-G-G-L-I-F-C-S-G-Q-A-A-V-K-D-G-N-F-V-P-G-T-I-Q-E-Q-T-R-L-T-I-E-N-L-A-E-V-L-R-V-A-G-S-S-L-E-K-L-V-K-V-N-I-F-L-T-D-I-D-D-F-A-A-M-N-E-V-Y-K-E-M-L-P-D-P-M-P-A-R-T-T-V-A-A-G-K-I-P-L-S-S-K-G-G-K-I-E-I-E-C-I-A-A-E"} +{"text": "### FUNCTION Catalyzes the oxidation of Mn The latter, acting as a diffusible redox mediator, is capable of oxidizing a variety of lignin compounds ### SEQUENCE -A-V-X-H-P-G-T-X-V-S-X-A-A-X-X-X-F-I-P-L"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-N-S-I-N-V-K-T-L-R-W-S-A-L-V-L-G-L-G-A-G-M-Y-E-H-R-S-H-I-Q-C-Q-K-Q-K-E-I-D-E-N-Y-H-R-Q-E-S-L-I-E-S-A-K-I-A-Y-L-N-T-K-N-T-P-P-K-E-D-S-M-L-P-N-L-K-K-D-S-E-D-F-D-M-D-E-F-V-K-E-L-E-K-N-V"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-A-N-T-K-K-S-A-I-N-Q-V-V-T-R-D-Y-T-I-H-M-H-K-R-L-Y-G-V-S-F-K-K-R-A-P-R-A-I-K-E-I-V-A-F-A-Q-K-H-M-Q-T-K-E-V-R-V-D-P-S-L-N-K-E-V-W-K-R-G-I-R-N-V-P-H-R-L-R-L-R-L-S-R-K-R-S-D-E-D-D-K-A-L-Y-T-Y-V-Q-A-V-D-V-A-N-P-K-M-E-T-T-V-V-E-E"} +{"text": "### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase to ubiquinol Promotes maturation of the iron-sulfur protein subunit sdh2 of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants May act together with SDHAF3 ### SEQUENCE -M-A-L-S-G-L-Q-R-Q-V-I-H-F-Y-R-R-C-L-H-A-A-K-A-K-E-Q-P-Y-N-E-R-W-M-A-F-V-H-Q-E-F-R-K-N-Q-T-I-S-K-R-D-F-F-Y-I-E-H-L-L-R-V-G-Q-R-Q-Y-E-A-Y-S-R-P-E-V-K-D-I-H-F-S"} +{"text": "### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane ### SEQUENCE -M-F-W-T-S-V-A-R-A-R-S-V-W-K-G-P-N-V-V-D-F-G-V-N-V-Q-Q-C-I-K-G-N-V-P-I-K-T-A-V-R-S-A-T-I-L-P-R-M-V-G-A-Q-F-M-V-H-N-G-K-S-Y-A-N-V-K-I-T-E-D-M-I-G-H-K-L-G-E-F-A-P-T-R-K-A-F-H-Y-R-Q-T-K-N-R"} +{"text": "### FUNCTION Required for the function of coenzyme Q in the respiratory chain May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes ### SEQUENCE -M-A-F-R-C-T-L-R-R-L-E-C-Y-R-A-S-R-L-M-P-Y-K-P-S-F-L-F-S-L-I-S-N-V-N-E-Y-E-R-F-V-P-F-C-Q-K-S-K-V-T-E-Y-D-P-K-T-G-Y-P-T-K-A-D-L-T-V-G-F-K-G-L-C-E-T-F-D-S-K-V-V-C-D-P-V-A-L-T-V-L-A-D-A-S-H-H-R-L-F-R-R-L-K-T-H-W-S-I-E-E-A-S-R-G-R-V-R-V-D-L-E-V-D-F-E-F-A-S-K-L-H-G-M-M-S-K-F-V-G-S-S-V-A-S-E-I-I-Q-G-F-V-Q-Q-A-K-I-K-H-K-L-E-S-E-N-E-K"} +{"text": "### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-P-R-Q-I-S-D-I-K-Q-F-L-E-I-A-R-R-K-D-A-T-S-A-R-I-K-K-N-T-N-K-D-V-K-F-K-L-R-C-S-K-Y-L-Y-T-L-V-V-A-D-A-K-K-A-E-K-L-R-Q-S-L-P-P-D-L-T-V-T-E-V-G-K-K-A"} +{"text": "### FUNCTION Essential for the assembly of ubiquinol-cytochrome c reductase It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b ### SEQUENCE -M-N-R-V-V-K-S-I-V-Y-G-V-G-I-V-G-F-G-Y-M-T-M-K-L-T-T-P-S-P-E-R-V-V-N-S-L-P-P-D-L-R-A-S-Y-E-M-N-K-K-D-R-S-Q-A-E-G-V-L-R-M-I-E-D-A-K-R-N-P-K-N-L-V"} +{"text": "### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane ### SEQUENCE -M-V-M-Y-E-L-F-C-I-T-R-P-A-A-N-A-T-R-T-S-S-P-T-L-A-M-N-I-A-K-N-C-G-R-A-I-L-D-N-K-G-V-V-V-D-V-E-S-M-G-L-K-E-L-A-K-P-I-K-K-L-N-Q-S-Y-S-F-G-H-W-W-S-M-T-F-Y-S-N-P-T-V-Q-S-E-I-Q-R-I-L-R-L-E-P-S-V-L-R-Y-M-I-V-K-K-A-D-K-L-S-D-L-M"} +{"text": "### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane bL19m is essential for respiration ### SEQUENCE -M-F-N-A-K-H-F-F-N-L-G-L-G-F-Q-W-L-Q-K-R-G-I-G-S-L-K-R-P-Y-N-F-P-K-P-V-P-G-P-K-H-K-D-V-L-S-L-F-E-K-K-C-R-S-V-L-D-E-Q-S-E-R-F-K-M-F-H-R-S-Q-P-N-R-V-R-P-G-A-V-L-L-V-E-S-Y-S-K-Y-P-S-K-D-S-V-N-R-F-A-G-Y-L-L-R-I-R-H-R-G-P-K-S-S-I-L-L-R-N-V-V-M-G-V-G-V-E-Y-L-L-P-I-Y-S-P-Q-I-K-R-I-V-V-L-K-E-N-G-L-S-K-R-P-R-R-A-Y-L-S-Y-L-R-Q-P-R-F-R-L-P-P-V-E-S-L-V-R-K-Y-I-E-Q-N-Q-H-K-P"} +{"text": "### FUNCTION Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules ### SEQUENCE -M-F-G-L-T-T-K-R-I-L-T-L-F-T-K-K-R-Q-T-L-V-E-Q-K-L-T-E-Y-M-I-A-G-E-K-T-D-N-Q-M-L-H-F-K-L-Q-V-E-T-A-T-P-T-L-D-Q-L-N-I-M-L-S-N-I-G-K-D-K-S-D-L-L-V-A-G-A-T-S-I-E-D-A-L-T-K-Y-Q-H-D-N-Q-L-F-R-R-P-C-L-V-D-W-D-K-G-K-V-S-P-Y-S-I-L-L-Q-T-R-D-F-S-K-L-L"} +{"text": "### FUNCTION Binds specifically to cytosolic chaperonin ### SEQUENCE -M-A-E-Q-P-S-R-Q-Q-I-L-Q-T-Q-Y-N-S-Y-K-S-R-L-Q-Q-I-A-Q-K-I-V-D-L-E-T-D-A-D-E-H-K-L-V-M-D-T-L-N-S-M-D-N-N-R-R-C-F-R-M-I-H-G-V-L-V-E-R-T-V-G-T-V-V-P-I-L-K-T-T-Q-E-G-I-Q-T-A-M-N-G-L-L-D-Q-Y-K-Q-L-E-A-E-F-Q-K-F-Q-K-D-N-K-I-Q-V-V-R-Q"} +{"text": "### FUNCTION Component of the cleavage factor I involved in pre-mRNA 3'-end processing ### SEQUENCE -M-T-D-Y-I-K-D-K-A-I-A-A-D-F-S-S-V-Q-F-R-F-D-N-Y-L-K-Q-N-F-N-F-G-R-S-A-L-L-N-S-G-N-G-R-D-S-G-S-K-M-G-S-V-V-C-K-H-W-L-R-G-L-C-K-K-G-E-Q-C-D-F-L-H-E-Y-N-L-K-K-M-P-P-C-H-F-Y-A-E-R-G-W-C-S-N-G-E-E-C-L-Y-L-H-L-D-P-S-K-Q-V-G-V-C-A-W-Y-N-M-G-F-C-P-L-G-P-I-C-R-G-K-H-V-R-K-P-R-P-C-P-K-Y-L-A-G-F-C-P-L-G-P-N-C-P-D-A-H-P-K-H-S-E-P-P-H-P-P-Q-K-R-K-D-W"} +{"text": "### FUNCTION Binds specifically to cytosolic chaperonin ### SEQUENCE -M-E-Q-V-P-V-L-A-E-D-Q-R-N-L-N-E-F-S-V-L-H-S-R-K-A-I-Q-E-L-D-I-K-N-L-K-T-Q-I-E-D-I-V-D-A-K-N-E-C-E-L-L-D-E-D-D-G-D-D-I-P-A-L-K-V-G-D-A-F-F-Q-V-S-L-P-V-L-L-D-Q-L-E-Q-S-E-E-S-L-E-K-Q-V-D-V-L-R-S-S-M-E-K-D-E-T-R-I-Q-E-L-K-S-M-L-Y-S-K-F-H-D-Q-I-N-L-D"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-S-M-F-G-I-G-K-N-N-Q-T-I-N-P-Q-N-I-A-M-A-E-Q-E-V-E-M-M-S-D-I-F-N-R-L-V-M-T-C-H-K-K-C-I-S-P-K-Y-Y-E-A-D-L-T-K-G-E-S-V-C-I-D-R-C-V-S-K-Y-F-E-A-N-Q-S-L-S-Q-H-M-Q-K-R-G-Q-E-N-P-T-P"} +{"text": "### FUNCTION Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit ### SEQUENCE -M-V-N-G-T-K-G-V-C-V-S-G-K-P-W-K-T-E-K-K-A-Y-N-R-S-G-L-A-D-A-Q-R-T-P-Y-E-K-R-M-E-Q-K-R-K-L-D-E-I-K-E-R-E-K-E-L-K-R-E-K-E-E-Q-R-A-A-H-A-E-K-I-R-T-R-R-Q-A-K-A-D-R-E-R-M-E-L-L-Q-A-K-L-H-Q-K-V-I-D-R-R-R-R-R-E-K-R-N-K-M-L-K-E-R"} +{"text": "### FUNCTION Required for the assembly of the mitochondrial respiratory chain complex IV , also known as cytochrome c oxidase May participate in merging the COX1 and COX2 assembly lines ### SEQUENCE -M-L-F-Y-R-F-K-S-W-Y-R-L-Q-A-K-K-S-P-F-I-Y-V-G-L-P-F-L-S-S-V-L-L-V-W-S-C-L-I-P-I-S-Q-V-K-F-N-R-R-D-E-Q-V-K-S-L-S-R-D-A-E-L-D-I-I-K-R-R-R-K-V-D-V-N-E-E-Y-Y-R-I-L-L-D-Q-L-N-L-Q-N-E-E-Y-E-N-K-R-V-K-R-L-K-G-E-P-T-W-E-G-N-S-S-D-K-E"} +{"text": "### FUNCTION May play a role in chromosome segregation through establishment of sister chromatid cohesion ### SEQUENCE -M-S-A-N-L-Q-N-E-N-P-E-V-K-E-L-N-Q-L-P-S-R-V-E-E-E-E-D-L-L-L-S-S-T-K-Q-W-L-T-E-I-E-S-E-Q-T-N-I-K-E-E-R-D-P-I-D-P-Q-E-I-Y-D-L-L-A-K-I-N-D-P-E-H-P-L-T-L-A-Q-L-S-V-V-K-L-E-D-I-E-V-V-D-N-V-E-G-D-S-Y-I-T-V-H-I-T-P-T-I-P-H-C-S-M-C-T-L-I-G-L-C-I-R-V-R-L-E-R-C-L-P-P-R-F-H-V-D-V-K-V-K-K-G-T-H-A-S-E-S-Q-V-N-K-Q-L-N-D-K-E-R-V-A-A-A-C-E-N-E-Q-L-L-S-V-L-N-G-M-M-A-T-C-V"} +{"text": "### FUNCTION Has a role in meiosis ### SEQUENCE -M-N-L-F-V-Y-I-A-Q-N-P-T-L-T-K-W-F-F-C-C-V-C-T-I-L-T-M-P-F-F-K-K-P-Y-R-K-R-G-I-S-R-T-P-Y-E-W-L-T-Y-A-D-K-C-V-I-E-L-S-K-S-E-L-K-P-N-E-E-K-E-L-P-K-D-I-K-E-D-C-K-T-V-E-E-K-E-K-V-V-P-R-K-P-L-Q-S-E-G-I-N-E-D-D-S-Q-K-N-G-E-L-I-V-L-H-G-I-N-H-Q-A-A-M-L-T-A-C-G-L-F-M-V-T-S-S-N-T-N-K-W-K-I-A-F-A-S-F-L-L-G-M-F-F-T-Q-F-G-F-Q-K-S-E-R-S-I-N-A-E-K-L-E-S-I-E-K-P-E-N-D-N"} +{"text": "### FUNCTION Component of the signal peptidase complex which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site ### SEQUENCE -M-P-K-Y-N-V-S-D-F-K-S-K-F-D-K-E-L-T-N-H-F-N-K-N-G-Y-K-Q-S-F-V-F-E-D-I-R-L-L-I-A-I-A-C-I-I-P-A-G-L-A-F-G-I-E-Y-V-Y-G-F-G-V-L-K-S-Y-L-K-Y-L-L-P-L-Y-F-L-A-S-C-L-L-T-F-W-S-S-V-V-K-G-S-T-V-Y-V-A-T-K-K-E-R-H-I-K-I-S-A-D-T-F-L-P-L-K-N-K-P-L-I-T-T-K-F-T-V-L-K-N-R-N-A-V-Q-L-E-W-S-V-P-V-A-H-I-F-E-E-D-G-Q-I-S-S-A-T-F-E-A-E-I-S-K-Y-L-S-Q-I-E-N"} +{"text": "### FUNCTION Has a role in meiosis ### SEQUENCE -M-E-Y-A-N-L-H-Y-V-K-E-S-S-N-L-E-R-S-S-T-Y-K-S-S-K-I-Q-D-E-A-K-Q-L-L-Y-D-Y-V-Y-I-K-E-K-L-L-T-T-S-S-N-S-L-T-H-Y-Q-W-Y-L-I-Y-K-H-T-C-R-C-F-Q-Q-V-V-R-I-V-Y-W-F-L-G-N-Q-V-I-R-E-N-F-S-I-K-K-R-K-P-H-N-H-I-P-Q-L-L-E-Q-C-T-C-I-A-E-S-F-E-G-I-Y-T-K-K-Q-I-L-Y-F-K-C-Y-G-T-F-K-T-W-K-K-I-A-N-F-P-H-L"} +{"text": "### FUNCTION Pre-ribosomal factor involved in 60S ribosomal protein subunit export from the nucleus ### SEQUENCE -M-A-K-K-Q-S-I-R-S-R-N-F-R-R-S-D-P-A-Y-D-L-D-S-S-T-A-I-E-N-E-T-K-L-S-V-K-E-K-V-A-K-E-I-A-N-I-A-L-R-S-G-G-S-E-S-N-G-I-S-K-K-K-K-N-K-K-Q-T-S-K-K-A-K-D-K-L-A-A-A-L-K-A-Q-A-R-E-E-R-L-D-T-K-I-S-K-S-L-Q-K-Q-E-K-L-K-A-R-K-Q-G-D-E"} +{"text": "### FUNCTION Acts as component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum ### SEQUENCE -M-V-S-I-Y-V-P-L-I-Y-I-T-I-L-M-G-S-M-Y-G-V-S-R-F-V-R-K-S-K-N-Q-E-S-K-P-V-S-E-E-W-F-G-E-N-Y-S-R-N-I-F-F-S-L-L-Q-Q-N-P-P-A-E-D-T-L-L-K-A-A-L-V-L-R-A-T-E-G-L-R-R-L-M-K-L-K-V-S-R-M-A-L-N-N-L-L-N-R-G-G-V-G-D-E-L-I-R-K-F-G-R-L-E-K-E-T-E-L-E-L-M-D-I-A-K-T-A-N-S-L-Q-P-G-W-N-Q-F-I-F-Q-T-C-N-E-I-I-E-N-E-K-I-H-S-I-I-D-N-I-P-K-D-I-D-S-I-S-Q-R-W-Q-T-E-K-I-L-Y-E-A-A-D-E-E-L-R-I-Q-A-Q-K-E-L-G-V-L"} +{"text": "### FUNCTION Required for 20S pre-rRNA processing ### SEQUENCE -M-F-D-D-P-S-K-R-L-T-Y-F-E-Y-A-V-G-V-L-L-C-S-W-P-V-M-K-Q-A-V-E-E-E-W-A-D-V-D-T-A-D-K-R-D-W-M-A-G-V-L-V-D-Y-I-T-V-T-S-D-V-E-A-W-D-V-E-E-L-I-L-Q-V-L-Q-D-E-F-N-V-G-S-I-E-D-D-S-P-Y-I-L-A-Q-D-L-V-N-V-W-K-A-A-C-E-D-N-Y-E-P-I-R-E-I-H-E-R-L-G-K-Q-L-L-E-K-E-E-G-K-E-K-T-R-E-E-S-N-P-P-V-L-V-E-D-E-T-I-V-D-A-E-D-G-G-A-A-Q-N-Q-Q-E-K-Q-Q-G-P-I-V-D-D-D-G-F-T-V-V-Q-K-R-R-R"} +{"text": "### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane uS17m may have a meiosis-specific role as it accumulates during the middle stage of sporulation ### SEQUENCE -M-K-L-N-Y-V-G-I-V-I-S-R-A-M-P-K-T-A-K-V-R-V-A-K-E-K-F-H-P-V-V-K-K-Y-V-T-Q-Y-Q-N-Y-M-V-Q-D-D-L-N-C-N-V-G-D-A-V-T-I-Q-P-C-R-P-R-S-A-T-K-R-F-E-I-I-K-I-L-S-T-A-N-R-M-S-P-A-S-E-I-S-K-E"} +{"text": "### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane Also has an extraribosomal function, being essential for mitochondrial genome integrity May interact with MHR1 to take part in the mtDNA repair mechanism ### SEQUENCE -M-M-I-E-I-I-P-K-I-S-I-P-K-N-G-L-G-S-F-T-R-P-C-R-R-I-E-F-S-Y-C-N-W-G-G-S-S-K-G-M-K-E-F-L-S-T-K-L-E-S-L-A-K-E-S-Q-D-V-E-F-H-V-T-N-R-Q-G-K-H-P-L-I-R-A-Y-Y-N-T-G-R-E-K-V-I-C-T-R-K-M-S-A-S-S-I-F-Q-K-A-I-L-C-R-D-S-D-G-L-K-P-R-L-I-K-Y-P-V-E-S-T-N-P-S-V-R-G-I-W-S-P-F-S-D-Q-A-K-P-H-E-I-Y-K-K-K-S-P"} +{"text": "### FUNCTION Has a role in meiosis ### SEQUENCE -M-R-L-Q-S-L-S-S-V-A-I-A-E-T-R-R-Q-I-I-L-T-I-I-N-S-L-V-Y-L-V-N-F-I-S-C-P-S-I-H-S-I-P-F-H-I-S-T-H-L-T-S-C-Q-A-N-I-S-L-L-K-I-V-G-L-H-C-P-F-H-R-R-G-I-A-S-L-S-V-C-V-A-L-H-W-I-A-F-S-C-S-V-M-C-H-F-A-W-S-C-A-L-P-C-F-V-D-S-F-F-P-S-N-F-F-L-R-T-Y-A-L-F-T-F-S-L-Q-L-W-S-G-N-D-L-Q-G-N-H-S-Y-L-A-T-P-T-R"} +{"text": "### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane ### SEQUENCE -M-P-V-F-T-K-E-A-L-E-R-L-P-I-Q-L-G-N-F-F-K-K-F-P-P-E-N-P-N-A-W-T-T-N-P-N-R-Q-N-P-F-L-A-T-R-N-P-Q-N-G-L-V-I-N-P-Y-Y-S-N-R-R-Q-A-E-I-Y-K-E-A-R-L-Q-N-L-D-N-L-L-P-Q-Q-M-S-W-Q-K-D-S-T-R-H-I-L-K-G-L-L-N-P-K-G-K-I-S-E-R-K-R-D-E-I-L-E-N-R-R-L-K-L-S-E-S-L-K-K-T-S-K-F-K-N-E-R-Q-K-A-S-K-I-A-K-P-S-P-F"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-V-Q-V-I-S-N-L-D-E-F-N-K-L-T-N-S-G-K-I-I-I-I-D-F-W-A-T-W-C-G-P-C-R-V-I-S-P-I-F-E-K-F-S-E-K-Y-G-A-N-N-I-V-F-A-K-V-D-V-D-T-A-S-D-I-S-E-E-A-K-I-R-A-M-P-T-F-Q-V-Y-K-D-G-Q-K-I-D-E-L-V-G-A-N-P-T-A-L-E-S-L-V-Q-K-S-L-A"} +{"text": "### FUNCTION Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion Transcriptional activator that induces the transcription of alpha-specific mating genes ### SEQUENCE -M-G-N-K-K-K-T-R-K-T-V-P-K-E-F-I-S-L-F-R-V-H-S-G-R-D-A-P-R-R-D-T-R-E-V-Q-K-S-K-K-H-G-F-R-F-T-S-L-P-D-L-P-V-A-S-N-A-L-Q-E-L-L-L-E-Y-G-L-L-N-D-I-K-W-D-S-K-G-L-K-A-S-K-N-K-K-T-K-L-K-P-I-N-S-F-I-A-F-R-S-F-Y-S-R-T-I-S-N-P-E-H-Q-R-E-L-S-S-K-L-A-D-V-W-T-Q-E-S-N-Q-E-V-W-K-Q-Y-T-Q-S-Y-N-N-Y-L-L-L-P-D-A-K-L-N-F-V-D-W-L-C-E-A-L-D-Y-T-I-D-N-T-T-P-Q-I-E-D-I-S-L-T-S-Y-N-Q-L-L-S-G-T-I-E-D-V-Y-I-M-K"} +{"text": "### FUNCTION Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca ### SEQUENCE -M-A-D-S-L-T-E-E-Q-V-S-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-Q-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-S-E-S-E-L-Q-D-M-I-N-E-V-D-A-D-N-N-G-T-I-D-F-P-E-F-L-T-M-M-A-R-K-M-K-D-T-D-S-E-E-E-I-R-E-A-F-K-V-F-D-R-D-N-N-G-F-I-S-A-A-E-L-R-H-V-M-T-S-I-G-E-K-L-T-D-D-E-V-D-E-M-I-R-E-A-D-Q-D-G-D-G-R-I-D-Y-N-E-F-V-Q-L-M-M-Q-K"} +{"text": "### FUNCTION Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella ### SEQUENCE -L-A-G-L-D-T-A-I-I-L-I-A-F-I-I-T-A-S-V-L-A-Y-V"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-I-P-D-E-I-P-Y-K-A-V-V-N-I-E-N-I-V-A-T-V-T-L-D-Q-T-L-D-L-Y-A-M-E-R-S-V-P-N-V-E-Y-D-P-D-Q-F-P-G-L-I-F-R-L-E-S-P-K-I-T-S-L-I-F-K-S-G-K-M-V-V-T-G-A-K-S-T-D-E-L-I-K-A-V-K-R-I-I-K-T-L-K-K-Y-G-M-Q-L-T-G-K-P-K-I-Q-I-Q-N-I-V-A-S-A-N-L-H-V-I-V-N-L-D-K-A-A-F-L-L-E-N-N-M-Y-E-P-E-Q-F-P-G-L-I-Y-R-M-D-E-P-R-V-V-L-L-I-F-S-S-G-K-M-V-I-T-G-A-K-R-E-D-E-V-H-K-A-V-K-K-I-F-D-K-L-V-E-L-D-C-V-K-P-V-E-E-E-E-L-E-F"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-D-F-E-Q-L-L-D-K-S-L-N-K-V-R-E-E-I-K-T-E-L-S-K-S-L-D-E-A-I-K-L-L-N-E-G-H-N-K-I-V-Q-E-Y-S-Q-R-I-N-E-L-I-V-K-T-K-E-E-I-E-G-E-K-A-R-L-E-V-E-N-K-R-T-L-L-V-E-K-E-Y-W-I-N-K-V-Y-E-R-V-L-G-K-I-G-E-V-V-K-T-K-E-Y-K-D-A-I-E-N-I-I-S-K-E-I-K-E-I-R-E-E-K-V-T-I-Y-C-S-P-N-D-K-L-M-I-E-K-I-V-G-N-N-K-N-V-T-V-K-T-D-E-K-M-L-G-G-I-K-I-Y-F-E-R-S-G-L-T-R-D-F-S-L-K-L-I-L-D-Q-V-F-D-S-M-R-G-K-I-S-D-M-L-F-G-G-K"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-I-S-S-S-K-R-D-E-L-I-V-S-K-I-R-N-G-T-V-I-D-H-I-P-A-G-R-A-L-A-V-L-R-I-L-G-I-R-G-S-E-G-Y-R-V-A-L-V-M-N-V-E-S-K-K-I-G-R-K-D-I-V-K-I-E-D-R-V-I-D-E-K-E-A-S-L-I-T-L-I-A-P-S-A-T-I-N-I-I-R-D-Y-V-V-T-E-K-R-H-L-E-V-P-K-Q-I-R-G-L-I-K-C-P-N-P-Q-C-I-T-N-N-D-V-E-A-E-S-R-F-I-T-I-S-I-K-P-L-K-L-K-C-K-Y-C-E-M-Y-I-T-E-D-D-V-I-R-Q-I-L"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-S-A-E-K-I-S-I-S-L-P-K-E-L-Y-R-E-L-E-D-F-I-I-R-K-G-I-P-D-R-S-K-I-F-Q-I-A-L-R-N-Y-L-D-E-N-R-D-G-N-E-I-I-Y-G-I-I-N-L-V-Y-D-H-E-E-A-S-E-A-L-T-E-I-Q-H-E-Y-N-D-S-I-I-S-T-L-H-L-H-V-S-E-K-I-C-I-E-A-I-A-V-K-G-E-K-R-K-L-V-E-L-N-N-K-L-G-Q-I-R-G-I-L-K-A-R-L-L-I-S-F-P-Y-E-K-T"} +{"text": "### FUNCTION Probable zinc metalloprotease whose natural substrate is unknown ### SEQUENCE -M-T-E-M-K-I-L-I-V-T-L-T-Y-I-E-K-S-I-I-D-E-I-V-N-N-L-S-S-Y-G-L-E-V-D-I-L-L-D-S-R-K-Y-L-P-I-S-A-F-N-W-E-R-L-Q-Y-D-A-E-K-V-L-S-F-L-K-S-I-H-D-F-N-Y-D-S-I-I-F-L-A-D-S-D-G-Y-I-D-G-Y-N-F-V-F-G-L-T-I-D-N-F-A-I-I-F-L-H-R-L-R-E-E-F-Y-N-R-K-P-D-L-D-L-F-M-K-R-V-V-K-E-V-T-H-E-V-G-H-T-L-G-L-S-H-C-N-T-T-G-C-V-M-N-F-S-N-S-V-E-D-V-D-K-K-Q-A-K-F-C-K-N-C-A-H-K-I-E-K-L-S-K-Y-L-Q-Q-K"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently ### SEQUENCE -M-R-Q-F-E-F-F-E-H-T-A-D-V-G-I-K-S-Y-G-R-S-L-E-E-A-F-S-N-A-A-L-G-V-F-E-V-I-T-D-T-S-K-V-R-P-V-E-Y-R-E-I-Y-L-N-G-Y-D-L-E-N-L-L-Y-K-W-I-E-E-L-L-Y-Y-Y-D-S-E-L-M-I-F-S-K-F-D-L-M-I-D-Q-D-S-I-T-L-E-G-K-A-W-G-E-R-F-N-D-K-I-H-E-R-R-T-V-V-K-A-M-T-Y-H-Q-L-S-I-E-K-T-E-S-G-Y-V-I-T-F-V-V-D-I"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-V-V-R-R-E-K-K-S-R-K-M-R-G-S-R-T-M-G-W-G-I-R-G-Q-H-R-D-R-G-S-Q-G-G-R-Q-I-G-M-H-K-E-K-W-S-W-L-V-K-Y-G-K-G-W-Y-G-K-H-G-F-R-N-P-T-T-K-L-T-S-A-I-S-L-R-K-L-N-E-L-L-E-S-G-Y-I-K-I-K-E-M-D-G-K-K-I-V-D-L-N-E-L-G-Y-N-K-L-L-G-G-G-S-I-S-I-P-V-T-I-K-V-G-K-A-T-N-K-A-I-Q-K-V-K-E-M-G-G-E-V-I-L-S-P-T-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-N-K-L-A-N-G-P-N-Y-K-V-K-P-R-R-R-R-E-G-K-T-N-Y-Y-K-R-Y-V-Y-V-I-S-K-Q-T-R-F-I-V-R-I-T-N-K-Y-V-I-V-Q-I-A-K-I-D-P-K-G-D-I-M-I-A-S-A-H-S-A-E-L-A-K-K-F-G-W-K-G-D-E-N-N-T-P-A-A-Y-L-T-G-Y-L-A-G-L-R-A-I-K-R-G-V-T-E-C-V-A-D-I-G-L-H-V-P-S-K-G-N-R-V-F-Y-V-I-K-G-A-I-D-A-G-L-K-I-P-I-G-D-I-S-I-E-N-D-R-I-K-G-E-H-I-A-K-Y-A-E-K-L-K-S-E-N-S-D-L-Y-S-K-L-F-S-R-Y-L-Q-R-G-L-N-P-E-N-L-P-S-H-F-E-E-I-L-N-K-I-K-S-S-G-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-N-L-K-A-Q-K-R-L-A-A-S-I-A-G-V-G-I-N-R-I-K-V-V-E-D-Y-I-E-D-V-Q-S-S-L-T-R-D-E-I-R-N-L-I-K-D-G-K-I-I-V-L-K-K-V-G-I-S-G-G-R-L-K-E-R-R-K-K-R-S-L-K-S-E-G-K-K-S-G-S-R-K-G-K-K-G-A-R-A-N-S-K-Q-M-W-V-K-R-V-R-K-I-R-A-Y-L-K-W-L-R-D-H-K-V-I-D-R-H-T-Y-R-E-L-Y-L-K-T-K-G-G-N-Y-K-G-V-S-D-V-R-N-V-L-I-Q-M-G-K-I-K-G"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-Q-I-V-I-L-R-E-E-I-E-I-P-K-N-V-V-V-D-L-K-G-S-I-I-K-I-K-G-P-K-G-E-V-V-K-D-F-S-F-A-K-G-I-Q-I-S-L-D-G-N-K-I-V-L-E-T-T-F-A-N-R-R-K-K-A-V-F-Y-S-I-V-S-H-I-K-N-M-I-T-G-V-T-K-G-Y-R-Y-Y-L-K-I-I-Y-T-H-F-P-T-S-V-K-V-V-G-N-E-V-Q-I-T-N-L-I-G-E-K-N-T-R-R-A-Q-I-L-E-G-V-K-V-T-V-K-G-E-D-I-V-V-E-G-P-N-L-E-A-V-A-Q-T-A-A-N-I-E-S-A-S-K-I-S-G-F-D-R-R-I-F-S-D-G-I-F-I-Y-K-K-E-V-I-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-F-V-N-P-L-A-N-A-L-T-S-I-Y-N-N-E-M-R-R-N-K-Q-A-I-I-M-P-A-S-K-L-V-I-N-V-L-R-V-M-Q-K-E-G-Y-V-G-E-F-E-Y-I-D-D-G-R-W-G-K-I-T-V-Q-L-L-G-R-V-N-K-C-G-P-I-T-P-R-Y-P-L-S-Y-R-Q-M-I-A-L-P-D-Y-V-R-R-Y-L-P-S-K-E-I-G-I-I-I-V-S-T-S-K-G-V-M-S-H-K-E-A-A-R-L-R-I-G-G-V-A-L-G-Y-V-Y"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-I-K-M-A-E-S-T-L-P-L-S-Q-N-P-M-R-K-V-K-L-S-K-V-T-V-N-I-G-L-G-E-S-G-D-R-L-Q-K-A-Y-Q-L-L-Q-E-L-T-G-A-K-P-V-Y-T-I-S-K-K-T-I-R-E-F-G-I-R-K-G-Q-E-I-G-V-K-V-T-L-R-G-A-Q-A-E-E-F-L-R-K-V-L-E-A-I-G-Y-R-L-K-K-S-S-F-D-D-Y-G-N-V-S-F-G-I-A-E-H-V-I-L-P-G-A-R-Y-D-P-E-I-G-I-F-G-M-D-I-A-I-T-L-E-R-A-G-Y-R-I-S-R-R-R-R-K-K-A-K-I-P-K-R-H-R-V-T-K-E-E-A-M-E-F-L-R-N-N-F-N-V-Q-L-V-E-G"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-V-S-L-K-P-S-K-Q-R-K-L-L-Y-T-L-P-L-H-Q-R-K-K-L-L-V-A-K-V-S-D-D-I-A-S-Q-Y-G-I-K-R-I-R-V-R-K-G-D-T-V-R-V-M-R-G-G-N-S-G-K-E-G-K-V-V-E-V-N-T-K-T-G-R-L-A-I-E-G-I-T-R-K-K-V-D-G-T-P-V-Y-V-W-I-H-A-S-K-V-M-I-T-K-L-D-L-S-D-P-R-R-R-E-K-L-E-K-S-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-V-S-K-G-K-T-V-K-D-P-G-I-P-N-I-T-I-P-E-K-V-C-E-D-E-D-C-P-Y-H-G-S-L-R-V-R-G-I-T-L-E-G-V-I-V-K-Y-R-G-T-K-A-A-V-I-E-R-Q-Y-L-Y-Y-D-S-K-Y-K-R-Y-E-R-R-R-S-R-I-H-A-H-V-P-P-C-I-N-V-R-E-G-D-K-V-I-I-G-E-C-R-P-L-S-K-S-I-S-F-V-V-L-G-K-V-S"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-A-S-W-K-Y-P-Q-L-D-V-D-E-L-K-I-A-K-A-V-I-R-D-V-P-E-S-I-R-D-L-Y-N-V-C-K-A-I-R-G-M-Y-L-N-D-A-K-D-F-L-N-R-V-L-E-E-K-E-A-L-P-F-W-R-Y-N-K-G-A-S-H-K-S-N-I-S-A-K-W-K-I-K-A-G-R-Y-P-K-K-A-I-R-Q-V-L-K-V-L-E-N-A-E-A-N-A-T-N-K-G-L-D-V-D-K-L-I-I-R-H-I-A-A-H-K-G-I-T-L-Q-R-Y-M-P-R-A-F-G-R-A-T-A-K-Y-R-R-T-S-N-I-E-V-I-L-E-E-V-E"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-L-E-I-P-P-E-W-K-N-F-K-Y-R-G-K-S-I-D-E-L-L-N-M-P-M-D-E-F-I-K-L-L-P-S-R-Q-R-R-S-L-K-R-G-F-T-D-A-Q-R-H-L-L-E-K-V-R-K-Y-R-R-E-G-K-F-N-K-T-I-K-T-H-V-R-N-L-V-I-L-P-E-L-I-G-L-K-M-A-V-Y-N-G-K-E-F-V-E-F-T-V-T-P-E-M-I-G-H-Y-L-G-E-Y-S-I-T-T-K-K-V-E-H-G-E-P-G-L-K-A-T-R-S-S-L-F-L-A-M-K-G"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-A-E-K-L-P-P-E-V-Q-A-Q-L-A-K-F-Q-Q-L-K-D-Q-L-D-R-L-L-L-E-K-S-T-I-E-N-E-L-R-E-I-N-K-V-L-E-E-L-S-V-L-N-A-D-A-T-I-Y-K-I-V-G-N-L-L-V-K-S-D-K-T-S-V-E-K-E-L-N-D-R-K-E-L-L-E-L-R-S-R-T-Y-Q-K-Q-E-S-I-L-R-K-Q-L-E-D-L-Q-A-K-I-N-D-M-L-S-K-Y-Y-P-Q-G-G-Q-T-G-I-K-A"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-N-S-I-Q-L-I-I-D-I-I-L-I-L-W-I-L-I-L-T-V-L-Y-F-K-R-R-Q-L-N-V-D-I-V-K-N-K-K-I-I-R-A-K-R-Y-I-V-F-Y-V-I-S-E-Y-K-V-K-G-D-D-L-E-R-V-I-R-N-S-L-K-D-L-L-G-S-V-W-L-N-I-A-N-P-K-V-V-T-Y-R-E-D-T-Q-E-G-I-I-S-T-N-R-V-G-Y-K-A-V-L-A-S-L-P-F-A-K-E-I-N-N-N-K-I-L-I-V-P-R-R-T-T-G-S-L-K-K-A-K-K-L-I-G-L-K"} +{"text": "### FUNCTION Catalyzes the formation of CDP-2,3-bis- and CTP This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-S-I-A-Y-D-L-L-L-S-I-L-I-Y-L-P-A-F-V-A-N-G-S-G-P-F-I-K-R-G-T-P-I-D-F-G-K-N-F-V-D-G-R-R-L-F-G-D-G-K-T-F-E-G-L-I-V-A-L-T-F-G-T-T-V-G-V-I-I-S-K-F-F-T-A-E-W-T-L-I-S-F-L-E-S-L-F-A-M-I-G-D-M-I-G-A-F-I-K-R-R-L-G-I-P-R-G-G-R-V-L-G-L-D-Q-L-D-F-V-L-G-A-S-L-I-L-V-L-M-R-V-N-I-T-W-Y-Q-F-L-F-I-C-G-L-A-F-F-L-H-Q-G-T-N-Y-V-A-Y-L-L-K-I-K-N-V-P-W"} +{"text": "### FUNCTION One of the integral membrane subunits of multisubunit membrane-bound -hydrogenase eha Eha is predicted to form large electron transfer complex and might catalyze energy-driven reduction of low-potential redox carriers ### SEQUENCE -M-I-I-H-V-T-Y-L-S-G-Y-I-T-G-I-I-S-S-I-I-I-S-A-I-L-G-L-P-L-A-P-E-R-P-A-R-H-S-W-T-P-S-A-I-F-P-A-P-I-I-A-M-G-L-V-A-I-C-I-K-L-G-V-T-G-M-Y-G-G-V-D-L-G-V-V-S-G-L-L-A-A-L-M-T-A-Y-F-L-E-D-I-F-P-R-P-E-D-L"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-E-Y-V-Y-A-A-L-L-L-H-S-V-G-K-E-I-N-E-D-N-L-K-A-V-L-Q-A-A-G-V-E-P-D-E-A-R-I-K-A-L-V-A-A-L-E-G-V-N-I-D-E-V-I-E-K-A-A-M-P-V-A-V-A-A-A-P-A-A-A-P-A-E-A-P-A-E-E-K-K-E-E-E-K-K-E-E-E-K-E-E-E-V-S-E-E-E-A-L-A-G-L-S-A-L-F-G"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-G-A-E-L-I-I-Q-E-I-N-R-E-A-E-R-K-I-E-Y-I-L-N-E-A-R-E-E-A-E-K-I-K-E-E-A-K-R-R-A-E-S-K-A-E-W-I-L-R-R-A-K-T-Q-A-E-L-E-K-Q-R-I-I-A-N-A-R-L-E-V-R-R-K-R-L-A-V-Q-E-E-I-I-R-N-V-L-D-E-V-R-K-R-L-Q-E-M-P-E-E-E-Y-F-E-S-I-K-A-L-L-K-E-A-V-E-E-L-K-E-G-K-V-R-V-Y-S-N-E-R-T-L-A-L-I-S-S-R-I-E-E-I-R-D-Y-L-G-S-I-S-I-E-I-G-S-A-I-S-T-M-G-G-V-I-V-E-T-E-D-G-R-I-R-I-D-N-T-F-E-A-R-M-E-R-F-E-G-E-I-R-A-K-I-A-K-V-L-F-G-G"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-K-V-V-V-M-G-D-S-D-T-V-T-G-F-R-L-A-G-V-H-E-A-Y-E-F-D-F-S-E-L-S-I-E-R-A-R-N-K-L-K-E-L-V-E-R-D-D-V-G-I-I-L-I-T-E-R-L-A-Q-R-I-G-D-L-P-Q-V-N-L-P-I-I-L-Q-I-P-D-K-F-G-S-I-Y-G-E-E-L-L-R-E-I-V-R-K-A-V-G-I-E-I-K-R"} +{"text": "### FUNCTION In vitro, binds efficiently double-stranded RNAs in a non-sequence specific manner ### SEQUENCE -M-A-G-K-L-Q-A-H-N-I-R-I-R-T-F-I-H-A-T-E-D-P-E-K-V-L-E-A-L-E-T-L-F-P-E-E-I-S-P-K-D-V-E-F-E-V-I-E-T-E-G-Y-F-G-N-P-I-L-V-V-D-A-E-I-K-H-S-R-N-I-R-K-F-L-E-N-L-R-G-L-L-S-K-E-D-R-K-Y-L-W-E-H-A-E-E-K-V-D-E-T-G-T-F-Y-I-R-F-D-K-Q-K-A-Y-L-G-E-V-K-V-S-E-G-E-D-V-I-H-V-R-I-K-V-K-A-F-P-M-K-K-E-A-V-V-K-A-V-R-E-W-L-E-G-E-D"} +{"text": "### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-A-W-K-V-S-V-D-Q-D-T-C-I-G-D-A-I-C-A-S-L-C-P-D-V-F-E-M-N-D-E-G-K-A-Q-P-K-V-E-I-I-E-D-E-E-L-Y-N-C-A-K-E-A-M-E-S-C-P-V-S-A-I-T-I-E-E-A"} +{"text": "### FUNCTION Catalyzes the conversion of 7,8-dihydroneopterin triphosphate and acetaldehyde ### SEQUENCE -M-K-R-V-V-S-I-K-R-R-I-Y-W-T-K-E-F-D-S-S-H-F-L-E-L-E-Y-E-S-K-C-R-R-L-H-G-H-T-Y-R-V-E-V-E-I-E-G-E-P-N-E-H-G-M-I-F-D-F-N-H-L-S-E-L-I-K-T-L-D-H-K-V-I-V-S-E-K-W-V-R-Y-E-E-G-Y-V-L-I-E-K-N-D-K-L-L-K-L-P-R-S-E-V-V-V-I-D-K-P-N-V-T-A-E-Y-I-A-E-W-I-S-E-R-I-L-E-N-A-G-E-N-V-R-E-I-R-V-R-V-W-E-D-P-R-S-Y-A-E-I-T-L-T-L-K-P-Q-G-S"} +{"text": "### FUNCTION Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A ### SEQUENCE -M-K-V-L-F-K-L-P-P-S-L-R-S-E-L-K-K-P-V-G-E-L-I-E-G-D-I-P-T-P-Y-L-K-V-K-D-I-L-T-N-E-D-P-L-V-T-V-G-D-V-V-T-E-N-I-M-K-V-G-L-N-P-N-L-A-I-Y-D-H-K-T-E-R-R-E-Y-K-P-N-I-R-S-V-E-G-V-L-I-T-V-K-N-P-P-G-T-I-T-L-P-L-L-K-A-I-K-K-A-Y-S-L-L-S-H-G-K-R-V-H-I-V-V-D-G-E-E-D-L-A-T-I-P-A-V-L-Y-A-P-I-G-T-T-V-I-Y-G-Q-P-K-K-G-I-V-L-I-K-V-T-N-E-C-K-R-R-C-A-K-I-M-R-R-M-E-V-V-R-N-G-D"} +{"text": "### FUNCTION Endonuclease that removes tRNA introns Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp ### SEQUENCE -M-K-K-V-I-E-F-Y-L-S-G-D-R-V-Y-S-T-R-E-K-A-I-N-Q-L-Y-N-N-R-G-Y-G-E-L-K-G-N-K-L-F-L-S-L-I-E-A-A-Y-L-V-E-R-G-W-I-K-V-L-D-E-D-R-E-L-T-F-E-E-I-F-K-L-G-K-R-K-D-E-D-F-D-I-K-Y-L-V-Y-K-D-L-R-D-R-G-Y-I-V-K-S-A-L-K-F-G-S-H-F-R-V-Y-R-K-N-A-E-H-S-D-W-L-I-W-V-L-R-E-S-E-K-L-S-P-N-D-M-T-A-R-V-R-V-A-H-G-V-R-K-N-M-V-M-A-I-V-D-E-D-N-D-V-V-Y-Y-K-I-E-W-I-K-F"} +{"text": "### FUNCTION Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide ### SEQUENCE -M-V-K-V-G-M-P-K-V-G-I-I-M-G-S-D-S-D-L-P-V-M-K-E-A-A-K-V-L-E-D-F-E-V-D-Y-E-M-K-V-I-S-A-H-R-T-P-E-R-L-H-E-Y-A-R-T-A-E-E-R-G-I-E-V-I-I-A-G-A-G-G-A-A-H-L-P-G-V-L-A-A-L-T-M-I-P-V-I-G-V-P-I-K-S-K-A-L-N-G-L-D-S-L-L-S-I-V-Q-M-P-P-G-I-P-V-A-T-V-G-I-D-G-A-K-N-A-A-L-L-A-L-E-I-L-S-I-K-Y-P-E-I-K-E-K-L-K-K-Y-R-E-D-M-K-R-K-V-E-E-K-S-K-K-L-E-E-L-G-W-R-K-Y-L-E-G"} +{"text": "### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-T-R-E-I-K-V-G-I-G-D-Y-A-V-G-K-G-E-G-I-I-S-T-Y-G-L-G-S-C-V-G-I-T-L-Y-D-R-V-T-K-V-G-G-L-L-H-A-L-L-P-E-A-A-R-Y-G-H-R-G-N-P-A-K-Y-V-D-T-G-L-Q-L-L-L-K-E-V-L-K-L-G-A-S-K-F-R-L-E-A-K-L-F-G-G-A-Q-M-F-Q-N-I-K-S-D-E-L-K-I-G-E-R-N-V-Q-T-A-K-R-E-L-K-K-L-G-I-R-L-V-A-E-D-T-G-G-R-G-G-R-T-I-Y-L-D-L-S-T-G-K-V-R-M-R-K-V-I-G-G-Q-V-I-E-K-V-Y"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-A-Q-S-N-K-E-L-E-K-L-A-Y-E-Y-Q-L-L-Q-A-Q-A-Q-L-L-A-Q-N-L-E-L-L-N-L-A-R-A-E-V-Q-T-V-K-E-T-L-E-N-L-K-K-I-E-E-E-K-P-E-I-L-V-P-I-G-A-G-S-F-L-K-G-I-I-V-D-K-N-N-A-I-V-S-V-G-S-G-Y-A-V-E-R-S-V-D-D-A-I-S-F-L-E-K-R-L-N-E-Y-D-D-A-I-K-K-T-Q-Q-A-L-T-E-L-E-K-R-L-G-D-V-A-K-K-A-Q-E-I-Q-Q-K-Q-A-M-G-S-F-K-V-K-K"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-Q-N-I-P-P-Q-V-Q-A-M-L-G-Q-L-E-S-Y-Q-Q-Q-L-Q-L-V-I-Q-Q-K-Q-K-V-Q-A-D-L-N-E-A-K-K-A-L-E-E-I-E-A-L-P-D-D-A-Q-V-Y-K-T-V-G-T-L-I-V-K-T-T-K-E-K-A-L-Q-E-L-K-E-K-V-E-T-L-E-V-R-L-N-A-L-N-R-Q-E-Q-K-I-N-E-K-V-K-E-L-T-Q-K-I-Q-A-A-L-R-P-P-T-A-G"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-D-L-V-R-F-S-I-S-I-P-A-E-L-L-E-K-F-D-R-I-I-E-E-I-G-Y-E-N-R-S-E-A-I-R-D-L-I-R-D-F-I-I-R-R-E-W-E-V-G-N-E-E-V-A-G-T-I-T-I-V-Y-N-H-D-E-G-D-V-V-K-E-L-L-D-L-Q-H-E-Y-L-D-E-I-I-S-T-L-H-V-H-M-D-E-H-N-C-L-E-V-I-V-V-K-G-K-A-K-R-I-K-M-I-A-S-R-L-M-S-L-K-G-V-K-H-G-K-L-V-M-T-S-T-G-K-E-L-L"} +{"text": "### FUNCTION eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA ### SEQUENCE -M-E-I-D-Y-Y-D-Y-E-K-L-L-E-K-A-Y-E-E-L-P-E-N-V-K-H-H-K-S-R-F-E-V-P-G-A-L-V-T-I-E-G-N-K-T-I-I-E-N-F-K-D-I-A-E-A-L-N-R-D-P-Q-H-L-L-K-F-L-L-R-E-I-A-T-A-G-T-L-E-G-K-R-V-V-L-Q-G-R-F-T-P-Y-L-I-A-N-K-I-K-K-Y-I-K-E-Y-V-I-C-P-V-C-G-S-P-D-T-K-I-I-K-R-D-R-F-Y-F-L-K-C-E-A-C-G-A-E-T-P-I-Q-H-L"} +{"text": "### FUNCTION Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein and RNA polymerase recruitment Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes ### SEQUENCE -M-S-R-K-N-K-A-L-L-E-I-A-K-D-I-G-G-D-E-A-V-E-I-V-K-A-L-E-K-K-G-E-A-T-D-E-E-L-A-E-I-T-G-I-R-V-N-T-V-R-K-I-L-Y-A-L-Y-D-E-K-L-A-D-F-K-R-I-K-D-E-E-T-G-W-Y-Y-Y-Y-W-H-L-E-T-K-R-L-P-E-I-I-R-A-R-K-L-R-E-L-E-R-L-K-K-M-L-Q-E-E-T-S-E-V-Y-Y-H-C-G-N-P-E-H-P-K-L-T-F-D-E-A-F-E-Y-G-F-T-C-P-I-C-G-E-I-L-Q-E-Y-D-N-S-A-V-I-E-E-L-K-K-R-I-E-E-L-E-I-E-L-G-L-R-P-S-P-K-K-E-K-K-K-T-R-A-K-A-K-R-K-T-R-K-K"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-R-V-R-G-R-A-W-K-Y-G-D-N-I-D-T-D-V-I-I-P-A-R-Y-L-N-T-S-D-P-K-E-L-A-K-H-V-L-E-D-L-D-P-E-F-R-S-K-M-K-P-G-D-I-I-V-A-G-E-N-F-G-C-G-S-S-R-E-H-A-P-L-A-I-K-A-A-G-V-S-C-V-I-A-K-S-F-A-R-I-F-Y-R-N-A-I-N-I-G-L-P-I-L-E-A-P-Q-A-V-D-R-I-E-T-G-D-E-L-E-V-D-F-S-S-G-E-I-R-N-L-T-K-G-E-V-Y-R-A-N-P-F-P-D-F-I-M-E-I-I-K-A-G-G-L-V-E-W-A-K-R-R-L-K-G"} +{"text": "### FUNCTION Putative transcriptional regulator ### SEQUENCE -M-K-T-F-L-T-E-Q-Q-I-K-V-L-V-L-R-A-K-G-L-K-Q-S-E-I-A-R-I-L-K-T-T-R-A-N-V-S-I-L-E-K-R-A-L-E-K-I-E-K-A-R-N-T-L-L-L-W-E-Q-I-N-S-K-V-S-V-S-V-K-A-G-E-D-I-F-T-I-P-D-R-L-F-K-E-A-D-K-A-G-V-K-V-P-Y-S-T-A-E-I-I-A-F-L-V-E-H-A-P-I-E-D-R-L-A-K-R-D-F-V-I-F-L-D-S-K-N-R-L-R-I-S-E-C-L-I-N-F-V-E-E-G-I-G-N-D"} +{"text": "### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-R-F-F-V-S-G-M-P-G-V-G-K-T-T-L-A-K-R-I-A-D-E-I-R-R-E-G-Y-K-V-G-G-I-I-T-Q-E-I-R-T-G-P-K-R-S-G-F-R-V-I-A-L-D-T-G-E-I-G-R-L-A-Y-V-G-Q-G-Y-P-R-V-G-R-Y-V-V-D-I-E-G-F-D-R-V-A-I-P-A-I-S-R-A-L-R-D-A-D-I-I-I-I-D-E-I-G-P-M-E-F-K-S-N-E-F-L-K-A-L-G-L-V-L-K-S-E-K-P-L-L-A-T-V-H-R-K-L-V-D-R-Y-R-P-L-G-R-Y-Y-W-L-T-P-E-N-R-N-E-V-F-A-E-I-L-M-E-I-R-K-V-L-G-R-N-E-N-A-G-N-K-A"} +{"text": "### FUNCTION Broad-specificity nucleoside monophosphate kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-L-I-A-I-T-G-T-P-G-V-G-K-T-T-I-A-K-L-L-A-E-K-L-G-Y-E-Y-V-N-L-R-D-F-A-L-E-K-G-C-G-R-E-V-D-G-E-V-E-V-E-I-D-E-L-A-Y-F-V-E-K-E-L-K-D-R-N-V-V-L-D-G-H-L-S-H-L-M-P-V-D-L-V-V-V-L-R-A-H-P-R-I-I-G-E-R-L-R-E-R-G-Y-S-K-E-K-I-G-E-N-V-E-A-E-L-V-D-A-I-L-I-E-A-I-D-E-H-E-N-V-I-E-V-D-T-T-N-K-T-P-E-E-I-V-E-E-I-I-G-L-I-K-S-G-V-K-R-R-V-G-I-V-D-W-S-E-V-Y-D-E-I-I-P-Y-L-R-L-G-G-E"} +{"text": "### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-V-D-T-N-N-V-K-L-R-I-E-N-I-V-A-S-V-D-L-F-A-Q-L-D-L-E-K-V-L-D-I-C-P-N-S-K-Y-N-P-E-E-F-P-G-I-I-C-R-F-D-D-P-K-V-A-L-L-I-F-S-S-G-K-L-V-V-T-G-A-K-S-I-H-D-I-E-R-A-V-A-K-L-I-E-K-L-K-G-I-G-V-K-F-K-R-A-P-L-I-D-I-Q-N-M-V-F-S-G-D-I-G-R-E-F-N-L-D-N-V-A-L-T-L-P-N-C-E-Y-E-P-E-Q-F-P-G-V-I-Y-R-V-K-D-P-R-A-V-I-L-L-F-S-S-G-K-I-V-C-S-G-A-K-S-E-A-D-A-W-E-A-V-R-K-L-L-R-E-L-E-K-Y-G-L-I-E-E-E-E-E-E-L"} +{"text": "### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-R-V-V-V-A-I-T-G-A-S-G-T-I-Y-G-I-K-L-Y-E-T-L-R-D-L-G-H-E-V-I-L-L-A-S-K-T-G-I-K-V-A-K-Y-E-T-G-I-E-V-K-P-D-F-S-E-D-E-L-F-A-P-I-A-S-G-S-Y-P-F-D-A-M-V-I-A-P-C-S-M-K-T-L-S-A-I-A-N-G-F-S-N-N-L-I-T-R-A-A-D-V-A-L-K-E-R-R-K-L-V-L-L-I-R-E-T-P-L-N-L-I-H-I-Q-N-M-L-K-I-T-Q-A-G-G-I-I-M-P-A-S-P-A-F-Y-H-K-P-G-T-I-D-D-M-I-K-F-I-I-G-K-I-L-D-V-L-G-I-N-H-N-L-Y-K-R-W-G-M-D-Y-N-D"} +{"text": "### FUNCTION S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 ### SEQUENCE -M-R-F-T-E-N-F-E-R-A-K-K-E-A-L-I-S-L-E-I-A-L-R-R-G-E-V-D-E-D-I-I-P-L-L-K-K-I-N-E-K-P-N-Y-F-T-T-S-S-C-S-G-R-I-S-I-M-E-M-P-D-F-G-D-K-V-N-A-K-W-L-G-K-W-H-R-E-V-S-L-D-E-V-L-E-A-I-R-K-H-R-E-G-Q-L-W-L-L-V-R-S-P-I-L-H-V-G-A-R-T-L-E-D-G-I-K-L-L-N-L-G-V-S-C-G-F-K-Y-S-N-I-K-S-I-S-D-R-K-L-I-V-E-I-R-S-T-E-R-L-D-A-L-L-G-E-N-G-E-I-L-V-S-D-D-Y-M-R-K-L-V-E-I-A-N-A-Q-V-R-R-F-K-R-K-L-K-R-F-E-E-R-I-E-E-L"} +{"text": "### FUNCTION Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide ### SEQUENCE -M-L-K-D-T-I-K-S-G-D-W-K-G-E-K-H-V-P-V-I-E-Y-E-K-E-G-D-L-V-K-V-E-V-S-V-G-K-E-I-P-H-P-N-T-P-E-H-H-I-A-W-I-E-L-Y-F-H-P-E-D-G-Q-F-P-I-L-V-G-R-V-A-F-T-S-H-D-D-P-L-T-E-P-R-A-V-F-F-F-K-T-K-K-K-G-K-L-Y-A-L-S-Y-C-N-I-H-G-L-W-E-N-E-V-Q-L-E"} +{"text": "### FUNCTION Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule ### SEQUENCE -M-A-K-W-R-C-K-I-C-G-Y-I-Y-D-E-D-E-G-D-P-D-N-G-I-S-P-G-T-K-F-E-D-L-P-D-D-W-V-C-P-L-C-G-A-P-K-S-E-F-E-R-I-E"} +{"text": "### FUNCTION Involved in ribosome biogenesis ### SEQUENCE -M-R-F-R-I-R-K-C-P-K-C-G-R-Y-T-L-K-E-T-C-P-V-C-G-E-K-T-K-V-A-H-P-P-R-F-S-P-E-D-P-Y-G-E-Y-R-R-R-L-K-R-E-L-L-G-I-G-R-K-E-K"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-I-E-V-G-E-Y-K-V-K-E-G-L-Y-Y-T-K-E-H-E-W-A-Q-V-L-E-D-G-T-V-L-V-G-I-T-D-Y-A-Q-K-E-L-G-D-I-A-Y-V-E-L-P-E-V-G-K-E-V-K-K-G-E-V-L-C-E-V-E-S-V-K-A-V-S-E-V-Y-A-P-V-S-G-E-V-I-E-V-N-E-E-L-S-D-S-P-E-K-I-N-E-D-P-Y-G-A-W-I-A-K-I-K-P-N-N-L-E-E-E-L-K-E-L-M-D-A-E-K-Y-A-E-F-L-K-S-L"} +{"text": "### FUNCTION May be involved in maturation of the 30S ribosomal subunit ### SEQUENCE -M-A-T-V-Y-D-V-P-G-D-L-L-V-E-R-V-A-Q-R-L-K-E-I-P-E-I-K-P-P-E-W-A-P-F-V-K-T-G-R-H-K-E-R-L-P-E-Q-E-D-W-W-Y-Y-R-V-A-S-I-L-R-R-V-Y-L-D-G-P-V-G-I-E-R-L-R-T-Y-Y-G-G-R-K-N-R-G-H-A-P-E-R-F-Y-K-A-G-G-S-I-I-R-K-A-L-Q-Q-L-E-A-A-G-F-V-E-K-V-P-G-K-G-R-V-I-T-P-K-G-R-S-F-L-D-K-I-A-T-E-L-K-K-E-L-E-E-I-I-P-E-L-K-K-Y"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-K-L-K-T-L-P-P-T-L-R-D-K-N-R-Y-I-A-F-E-I-I-S-D-D-E-F-T-K-D-E-V-K-S-L-I-W-E-A-S-L-R-V-L-G-E-L-G-T-A-L-A-K-P-W-F-I-K-Y-D-P-K-T-K-T-G-I-V-R-C-D-R-E-Y-V-E-H-L-R-F-A-L-M-L-A-T-D-F-N-G-K-R-L-I-I-R-T-L-G-V-S-G-T-I-K-R-L-K-K-K-F-L-S-Q-Y-G-W-K"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-K-A-R-I-K-L-A-S-T-N-V-R-S-L-E-E-V-A-N-Q-I-K-Q-I-A-E-R-T-G-V-R-M-S-G-P-I-P-L-P-T-K-R-I-R-I-V-T-R-K-S-P-D-G-E-G-S-A-T-F-D-R-W-E-L-R-I-H-K-R-L-I-D-I-E-A-D-E-R-A-M-R-Q-I-M-R-I-R-V-P-E-D-V-T-I-E-I-E-L-I-S"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-L-K-T-T-L-L-L-I-I-G-G-G-L-G-A-L-A-R-Y-Y-I-S-G-I-L-P-V-Y-K-D-F-P-L-G-T-L-L-V-N-S-I-A-S-F-I-L-G-Y-L-Y-G-L-L-F-F-G-F-E-V-S-S-E-W-R-I-F-L-G-T-G-F-C-G-G-L-S-T-F-S-T-F-S-Y-E-T-F-S-L-L-R-E-G-E-Y-L-L-A-F-M-N-V-V-A-N-V-L-V-T-I-T-L-V-F-L-G-F-I-L-A-R-R"} +{"text": "### FUNCTION DNA-binding protein involved in the repression of transcription of a large number of genes, thereby arresting growth, in response to environmental changes ### SEQUENCE -M-R-V-S-L-D-E-I-D-R-R-I-I-K-I-L-Q-K-D-G-K-A-P-L-R-E-I-S-K-I-T-G-L-A-E-S-T-I-H-E-R-I-K-K-L-R-E-S-G-V-I-R-K-F-T-A-I-V-N-P-E-A-L-G-Y-S-M-L-A-F-I-L-I-K-V-K-A-G-K-Y-A-E-V-A-S-N-L-V-K-Y-E-E-I-M-E-V-Y-E-T-T-G-D-Y-D-M-V-V-K-I-R-T-K-N-S-E-E-L-N-S-F-L-D-V-I-G-S-I-P-G-V-E-G-T-H-T-M-I-V-L-K-T-H-K-E-T-T-E-L-P-I-K"} +{"text": "### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-M-P-M-N-P-K-Q-L-K-K-L-M-K-Q-L-D-M-K-Q-L-D-G-V-K-E-V-I-I-K-L-E-N-K-E-I-V-I-K-E-P-V-V-T-V-I-R-A-M-G-E-K-M-Y-Q-I-A-G-G-T-E-E-E-R-V-V-L-K-I-S-E-E-D-I-K-L-V-M-E-Q-A-G-V-D-Y-E-T-A-K-K-A-L-E-E-A-G-G-D-L-A-E-A-I-L-R-L-T-D-Q"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently -methyltransferase PAB1947 against aggregation and increases its specificity ### SEQUENCE -M-K-R-W-E-H-Y-E-H-T-A-D-I-G-I-R-G-Y-G-D-S-L-E-E-A-F-E-A-V-A-I-A-L-F-D-V-I-V-N-V-N-K-V-E-K-K-E-V-R-E-V-E-V-E-G-E-D-L-E-S-L-L-Y-N-F-L-E-E-L-L-V-I-H-D-I-E-G-L-V-F-R-D-F-E-V-K-I-E-K-T-E-K-G-Y-K-L-K-A-K-A-Y-G-E-K-L-D-P-E-K-H-E-P-K-E-E-V-K-A-I-T-Y-H-D-M-K-I-E-K-L-P-D-G-R-W-M-A-Q-L-V-P-D-I"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-F-K-F-K-Q-V-I-V-V-R-K-D-L-K-L-S-K-G-K-L-A-V-Q-V-A-H-G-A-V-T-A-A-F-K-A-Y-K-E-K-R-E-W-F-E-K-W-F-H-E-G-Q-K-K-V-V-V-K-V-E-S-L-D-E-L-F-K-L-K-A-E-A-E-K-L-N-L-P-T-A-L-I-Q-D-A-G-L-T-E-I-P-P-G-T-I-T-V-L-A-I-G-P-G-P-S-E-I-I-D-K-V-T-G-H-L-K-L-L"} +{"text": "### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-P-K-K-E-R-K-V-E-G-D-E-V-I-R-V-P-L-P-E-G-N-Q-L-F-G-V-V-E-Q-A-L-G-A-G-W-M-D-V-R-C-E-D-G-K-I-R-R-C-R-I-P-G-K-L-R-R-R-V-W-I-R-V-G-D-L-V-I-V-Q-P-W-P-V-Q-S-D-K-R-G-D-I-V-Y-R-Y-T-Q-T-Q-V-D-W-L-L-R-K-G-K-I-T-Q-E-F-L-T-G-G-S-L-L-V-E"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-W-A-L-A-D-A-I-V-R-T-A-L-D-Y-A-Q-K-E-N-A-S-K-I-L-A-I-K-V-V-L-G-E-L-Q-D-V-N-A-E-V-V-E-F-A-M-K-E-L-L-R-G-T-I-G-E-G-A-E-I-I-F-E-E-E-E-A-V-F-R-C-R-N-C-G-H-E-W-K-L-K-E-V-K-D-K-L-D-E-R-I-R-E-D-I-H-F-I-P-E-V-V-H-A-F-I-S-C-P-N-C-G-S-H-D-F-E-V-V-K-G-R-G-V-Y-I-A-G-I-K-I-E-K-E-E-G-E"} +{"text": "### FUNCTION DNA-binding protein that negatively regulates its own transcription Interferes with RNA polymerase recruitment by inhibiting the association of RNAP with the TBP-TFB promoter complex ### SEQUENCE -M-V-D-E-R-D-K-I-I-L-D-I-L-S-K-D-A-R-T-P-F-T-E-I-A-K-I-L-G-I-S-E-T-A-V-R-K-R-V-K-A-L-E-E-K-G-I-I-E-G-Y-T-I-K-I-N-P-K-K-L-G-Y-S-L-V-T-I-T-G-V-D-T-R-P-E-K-L-F-E-V-A-E-K-L-K-E-F-E-F-V-R-E-L-Y-L-S-S-G-D-H-M-I-M-A-V-I-W-A-K-D-G-E-D-L-A-D-I-I-S-N-K-I-G-K-I-D-G-V-T-K-V-C-P-A-I-I-L-E-R-L-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-I-I-N-A-E-G-L-I-L-G-R-L-A-S-R-V-A-K-M-L-L-E-G-E-E-V-V-I-V-N-A-E-K-A-V-I-T-G-N-R-E-V-I-F-S-K-Y-K-Q-R-T-G-L-R-T-L-T-N-P-R-R-G-P-F-Y-P-K-R-S-D-E-I-V-R-R-T-I-R-G-M-L-P-W-K-T-D-R-G-R-K-A-F-K-R-L-K-V-Y-V-G-I-P-K-E-F-K-D-K-Q-L-E-T-I-V-E-A-H-V-S-R-L-S-R-P-K-Y-V-T-V-G-E-V-A-K-F-L-G-G-K-F"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-D-F-R-H-I-V-R-V-A-G-V-D-L-D-G-N-K-Q-L-R-W-A-L-T-A-I-K-G-V-G-I-N-F-A-T-M-V-C-R-V-A-G-L-D-P-F-M-K-A-G-Y-L-T-D-E-Q-V-K-K-I-E-E-I-L-Q-D-P-V-A-H-G-I-P-R-W-A-V-N-R-P-K-D-Y-E-T-G-R-D-L-H-L-I-T-A-K-L-D-M-A-I-R-E-D-I-M-R-L-R-R-I-R-A-Y-R-G-I-R-H-E-L-G-L-P-V-R-G-Q-R-T-R-S-N-F-R-R-G-Q-T-V-G-V-S-R-K-K-K"} +{"text": "### FUNCTION Binds and compact DNA ### SEQUENCE -M-A-E-L-P-I-A-P-V-D-R-L-I-R-K-A-G-A-Q-R-V-S-E-K-A-A-K-L-L-A-E-H-L-E-E-K-A-L-E-I-A-K-K-A-V-D-L-A-K-H-A-G-R-K-T-V-K-V-E-D-I-K-L-A-I-R-S"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-I-T-T-G-R-V-W-K-F-W-D-N-V-S-T-D-E-I-T-P-G-R-Y-N-L-T-K-D-P-Q-E-L-A-R-I-A-F-I-E-V-R-P-E-F-A-E-K-V-R-R-G-D-V-V-V-G-G-K-N-F-G-I-G-S-S-R-E-S-A-A-L-A-L-K-A-A-G-V-S-G-I-I-A-K-S-F-G-R-I-F-Y-R-N-A-V-N-L-G-I-P-L-L-I-G-D-T-D-E-L-E-D-G-D-V-I-T-V-N-W-E-T-G-E-V-R-K-N-G-Q-T-L-Q-F-E-P-L-P-G-F-L-L-E-I-V-R-E-G-G-I-L-E-F-I-R-R-R-G-D-L-C-I-G"} +{"text": "### FUNCTION Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP ### SEQUENCE -M-S-K-F-V-I-W-T-S-E-L-D-S-R-L-S-K-K-Y-G-R-V-V-P-R-N-L-A-V-E-R-P-S-I-E-E-I-E-E-A-A-K-S-L-G-F-K-V-L-Q-V-E-R-E-K-L-N-P-K-L-S-G-I-D-E-D-L-R-T-Y-G-R-I-I-I-E-S-P-Y-G-K-A-K-T-L-K-I-I-A-Q-K-I-R-E-L-R-R-R-R"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-T-E-E-H-V-V-Y-I-G-K-K-P-V-M-N-Y-V-L-A-V-I-T-Q-F-H-E-G-A-K-E-V-S-I-K-A-R-G-R-A-I-S-R-A-V-D-V-A-E-I-V-R-N-R-F-L-K-D-D-V-D-V-K-E-I-K-I-G-T-E-E-L-P-T-A-D-G-R-T-T-N-T-S-T-I-E-I-V-L-A-R-K-A"} +{"text": "### FUNCTION Probable zinc metalloprotease whose natural substrate is unknown ### SEQUENCE -M-M-G-M-I-I-I-V-P-I-G-E-V-P-G-D-V-L-A-F-L-Q-N-S-L-S-G-F-Y-A-K-Y-G-I-E-V-R-L-V-G-G-L-S-L-S-K-F-Q-H-A-F-D-F-E-R-R-Q-F-L-A-R-Y-F-L-P-V-L-S-Y-I-R-K-D-F-N-A-K-A-A-L-G-V-V-N-V-D-I-Y-E-L-G-L-N-F-I-F-G-L-A-H-P-G-L-R-V-A-I-I-S-L-Y-R-L-Y-P-E-F-Y-G-N-P-P-D-R-K-L-L-K-E-R-A-L-K-E-A-M-H-E-L-G-H-V-F-G-L-E-H-C-P-N-P-K-C-V-M-H-F-S-N-S-I-I-D-T-D-I-K-S-W-M-Y-C-E-K-C-L-R-K-L-E-K-N-L-T-R-S-Y-V"} +{"text": "### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-D-P-Y-K-V-I-I-R-P-V-I-T-D-K-A-I-S-L-I-E-K-E-N-K-L-T-F-I-V-D-R-R-A-T-K-Q-D-I-K-R-A-I-E-E-I-F-N-V-K-V-E-K-V-N-T-L-I-T-P-K-G-E-K-K-A-Y-V-K-L-K-P-E-Y-S-A-S-E-I-A-A-R-L-G-L-F"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-K-E-F-R-Y-R-G-Y-T-L-E-Q-L-M-N-M-S-L-E-E-L-A-K-L-L-P-A-R-Q-R-R-S-L-K-R-G-L-T-P-E-Q-K-K-L-L-R-K-I-R-L-A-K-K-G-K-Y-N-K-P-I-R-T-H-C-R-D-M-I-V-L-P-E-M-V-G-L-T-I-Y-V-H-N-G-K-E-F-V-P-V-E-I-K-P-E-M-I-G-H-Y-L-G-E-F-A-P-T-R-K-R-V-Q-H-G-A-P-G-I-G-A-T-R-S-S-M-F-V-A-V-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-G-R-R-F-D-Y-S-F-Q-N-F-D-P-E-R-M-A-R-A-S-G-R-D-L-R-I-S-P-K-L-A-V-E-V-C-R-E-L-R-G-M-M-L-N-D-A-L-R-Y-L-D-D-V-I-A-L-R-R-P-V-P-L-K-R-Y-N-D-S-Q-G-H-K-P-G-K-G-F-G-P-G-R-Y-P-V-K-V-A-K-A-I-K-K-V-L-L-N-A-Q-N-N-A-K-Q-K-G-L-D-P-D-K-L-R-I-I-H-I-A-A-H-R-G-P-V-L-R-G-W-Y-P-R-A-F-G-R-P-T-P-F-N-E-Q-T-T-H-I-E-V-V-V-E-E-V-R-R"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-R-R-N-G-K-E-R-K-D-R-T-S-G-G-S-Q-R-P-Y-Q-E-I-V-G-R-T-W-I-F-R-G-S-H-R-G-R-V-T-K-R-N-I-I-W-H-E-L-I-G-L-K-V-R-V-V-N-S-M-H-P-G-F-V-G-I-E-G-Y-V-V-D-E-T-R-N-M-L-V-I-V-G-D-K-V-W-K-V-P-K-D-V-C-I-F-E-F-E-T-E-D-G-A-K-I-K-I-P-G-E-R-L-V-G-R-P-E-M-R-L-K-K-R-W-R-K-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-V-R-D-I-G-L-R-I-Q-P-P-A-E-K-C-D-D-P-K-C-P-W-H-G-H-L-K-I-H-G-R-V-F-E-G-I-V-V-S-D-K-P-R-K-T-V-T-V-E-R-Q-Y-Y-H-Y-L-K-K-Y-E-R-Y-E-L-R-R-S-R-I-H-A-H-N-P-P-C-I-N-A-K-V-G-D-R-V-L-I-A-E-T-R-P-L-S-K-T-K-H-F-V-V-V-A-V-L-E-R-A-E-E-R-R"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-A-K-K-G-A-G-A-T-R-G-I-T-P-V-R-P-T-R-A-I-P-V-G-A-Y-L-T-V-A-D-N-S-G-A-K-V-I-Q-V-I-G-V-V-E-Y-H-G-T-R-R-R-L-A-S-A-G-V-G-D-M-V-V-A-T-V-K-K-G-R-P-D-M-R-H-Q-V-V-R-A-V-I-I-R-Q-R-K-E-Y-R-R-L-D-G-M-R-I-K-F-E-D-N-A-A-V-I-V-T-P-E-G-V-P-R-G-T-E-I-R-G-P-V-A-R-E-A-A-E-R-W-V-R-I-G-S-I-A-S-I-I-V"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-R-L-N-S-K-Q-P-R-K-Q-R-K-F-L-Y-N-A-P-L-H-L-R-Q-K-M-M-A-A-P-L-S-K-E-L-R-E-K-Y-K-I-R-N-L-P-V-R-V-G-D-K-V-R-I-M-R-G-D-F-K-G-H-E-G-K-V-V-E-V-D-L-K-R-Y-R-I-Y-V-E-G-A-T-L-R-K-T-N-G-T-E-V-F-Y-P-I-H-P-S-N-V-M-I-I-E-L-N-L-D-D-E-R-R-K-K-I-I-E-R-R-A-G"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-I-T-I-P-N-R-E-E-I-L-A-D-W-E-A-H-P-M-R-K-P-R-I-E-K-V-T-I-N-I-G-V-G-E-S-G-E-R-L-T-K-A-E-I-M-L-E-R-L-T-G-Q-K-P-I-R-R-K-A-K-K-T-N-R-D-F-G-I-R-R-G-E-P-I-A-V-K-V-T-L-R-G-P-K-A-Y-E-M-L-K-R-L-L-A-A-V-D-N-R-L-K-A-S-S-F-D-E-H-G-N-V-C-F-G-I-D-E-H-I-N-I-P-G-V-E-Y-D-P-E-I-G-I-F-G-M-D-V-C-V-T-L-E-R-P-G-F-R-V-A-R-R-K-R-K-R-A-K-I-P-T-R-H-K-L-T-K-E-E-G-M-V-Y-M-M-E-E-F-G-V-E-I-V-E-E-E-G"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-L-L-D-P-L-A-N-A-L-S-H-I-T-N-S-E-R-V-G-K-R-E-V-Y-I-K-P-A-S-K-L-I-G-E-V-L-R-V-M-Q-K-Y-G-Y-I-G-E-F-E-F-I-D-D-G-R-A-G-V-Y-R-V-Q-L-L-G-K-I-N-K-A-G-A-I-K-P-R-F-P-V-K-A-R-D-Y-E-R-W-E-K-R-F-L-P-A-F-E-F-G-I-L-I-V-S-T-S-Q-G-V-M-S-H-K-E-A-R-E-K-G-I-G-G-R-L-I-A-Y-V-Y"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-P-V-D-A-W-V-R-E-E-I-E-I-P-E-G-V-E-V-S-V-Q-G-N-T-V-K-V-K-G-P-K-G-E-V-E-R-E-L-F-W-P-G-V-K-I-F-V-E-G-G-K-V-V-I-Y-K-D-F-P-R-R-K-D-V-A-I-V-R-T-F-K-A-H-I-N-N-M-I-K-G-V-T-E-G-F-T-Y-K-L-K-V-V-Y-S-H-F-P-I-T-V-K-V-Q-G-D-E-V-I-I-E-N-F-L-G-E-K-A-P-R-R-A-K-I-L-P-G-V-T-V-K-V-K-G-Q-E-I-I-V-E-G-I-D-K-E-A-V-G-Q-T-A-A-N-I-E-Q-A-T-R-I-T-K-W-D-R-R-V-F-Q-D-G-I-Y-I-V-E-K-A-G-K-P-I-T-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-T-L-K-M-Q-R-R-V-A-A-E-L-L-K-C-G-E-N-R-I-W-I-D-P-E-R-V-D-D-V-A-S-A-I-T-R-E-D-I-R-R-L-I-K-E-G-V-I-K-K-K-P-V-K-G-Q-S-R-Y-R-A-R-I-R-H-E-Q-K-K-K-G-R-H-R-G-P-G-S-R-K-G-K-K-T-A-R-M-G-K-K-E-L-W-I-K-T-I-R-A-L-R-K-E-L-R-K-L-K-E-Q-K-K-I-D-R-R-T-Y-R-M-L-Y-I-R-A-K-G-G-Q-F-K-S-K-H-Q-L-Y-M-F-L-E-E-H-N-L-L-K-K-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-I-R-R-R-K-K-V-R-K-L-R-G-S-H-T-H-G-W-G-C-K-K-K-H-R-G-G-G-S-K-G-G-R-G-M-A-G-T-G-K-R-N-K-S-K-W-T-W-T-I-K-Y-A-P-D-H-L-G-K-R-G-F-S-R-P-P-E-V-Q-R-E-V-R-T-V-T-L-K-S-I-D-E-N-L-D-E-L-L-Q-K-G-I-A-Y-E-E-E-G-K-I-I-V-D-T-T-Q-F-A-D-K-V-L-G-T-G-K-I-T-K-P-L-V-I-K-A-R-A-F-S-S-K-A-E-E-K-I-K-A-A-G-G-E-A-V-L-V"} +{"text": "### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate ### SEQUENCE -M-G-K-A-Q-S-V-R-F-K-V-S-K-L-M-A-Y-I-L-R-H-D-P-W-S-F-N-L-Q-P-D-E-E-G-F-V-D-L-E-E-F-V-N-A-I-R-R-V-Y-P-W-V-T-K-E-F-I-L-D-I-V-E-R-D-E-K-E-R-Y-E-V-K-E-G-K-I-R-A-R-Y-G-H-S-Y-P-V-I-L-D-H-K-E-D-K-E-S-K-T-L-Y-H-G-T-I-R-E-N-L-E-G-I-M-R-E-G-I-K-P-M-K-R-Q-F-V-H-L-S-L-N-Y-E-D-A-Y-N-T-G-R-R-H-G-S-N-V-V-V-L-M-I-D-A-D-C-L-R-K-K-G-F-K-I-L-K-A-G-K-K-V-R-I-V-K-Y-V-P-V-D-C-I-V-G-E-L"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-S-D-F-N-I-V-G-V-I-K-V-M-P-S-D-P-E-V-N-L-D-E-L-E-E-K-L-K-A-V-I-P-E-K-Y-G-L-A-K-V-E-R-E-P-I-A-F-G-L-V-A-L-K-F-Y-V-L-G-K-D-E-E-G-Y-S-F-D-E-V-A-E-K-F-K-E-V-E-N-V-E-S-A-E-V-E-T-V-S-R-I"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-P-E-L-Q-E-R-I-R-N-F-L-K-E-S-K-R-V-F-L-V-T-R-K-P-G-W-E-E-Y-K-K-A-A-K-I-T-G-L-G-I-I-L-I-G-L-I-G-M-L-I-R-I-M-G-I-L-V-L-G-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-K-K-Q-V-V-E-V-L-V-E-G-G-K-A-T-P-G-P-P-L-G-P-A-I-G-P-L-G-L-N-V-K-Q-V-V-D-K-I-N-E-A-T-K-E-F-A-G-M-Q-V-P-V-K-I-I-V-D-P-V-T-K-Q-F-E-I-E-V-G-V-P-P-T-S-Q-L-I-K-K-E-L-G-L-E-K-G-S-G-E-P-K-H-N-I-V-G-N-L-T-M-E-Q-V-I-K-I-A-K-M-K-R-N-Q-M-L-A-L-T-L-K-A-A-A-K-E-V-I-G-T-A-L-S-M-G-V-T-V-E-G-K-D-P-R-E-V-Q-R-E-I-D-E-G-V-Y-D-E-L-F-E-K-A-E-K-E"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-D-V-K-Y-D-L-N-S-Y-V-R-V-L-K-L-A-S-T-P-S-W-Q-E-F-S-Q-I-S-K-I-A-G-A-G-I-F-L-V-G-L-L-G-F-I-I-F-A-V-M-S-F-L-P-G-G-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-S-S-E-E-Q-E-D-V-D-E-D-I-Q-Y-F-V-R-I-G-Q-T-D-L-D-G-T-K-T-V-E-R-A-L-A-E-L-G-G-V-G-R-R-V-A-R-I-V-A-D-E-A-G-V-D-R-T-A-T-M-G-G-L-E-D-D-A-I-E-S-V-T-D-A-V-D-S-F-T-E-H-A-P-A-W-L-A-N-R-Q-N-D-F-Y-T-G-E-N-Q-H-I-T-G-T-D-V-E-L-T-R-D-Q-D-I-N-R-M-R-M-I-R-S-Y-K-G-I-R-H-E-R-G-Q-K-V-R-G-Q-R-T-K-S-T-G-R-T-E-G-T-I-G-V-N-V-E-A-I-K-E-E-Q-A-E-D-D-A-A-D-G-G-E-E"} +{"text": "### FUNCTION Molecular chaperone Seems to fulfill an ATP-independent, HSP70-like function in protein folding May protect essential factors of cell proliferation during heat shock No role in calpain activation ### SEQUENCE -M-S-T-I-V-R-K-L-I-S-T-A-N-A-A-K-P-V-A-P-Y-N-Q-A-V-V-A-D-R-T-V-Y-V-S-G-C-L-G-L-D-K-D-T-M-K-L-V-P-G-G-P-T-E-Q-A-Q-K-A-L-E-N-L-E-A-V-L-K-A-A-D-S-G-V-D-K-V-I-K-N-T-V-F-L-K-D-L-N-D-F-G-A-V-N-E-V-Y-K-R-V-F-N-K-D-F-P-A-R-S-C-F-Q-V-A-K-L-P-M-D-A-L-V-E-I-E-C-I-A-L-T-G-S-V-E-T-K-T-V-Q"} +{"text": "### FUNCTION Involved in mitochondria homeostasis ### SEQUENCE -M-K-R-L-K-A-Y-L-K-D-G-I-N-V-A-A-V-M-C-L-G-D-T-I-S-Q-F-F-F-D-K-K-S-L-D-E-W-D-A-G-R-T-L-R-F-G-I-V-G-L-V-F-V-G-P-T-L-R-R-W-Y-H-F-L-E-S-R-V-P-K-T-Y-S-P-M-R-R-G-V-T-K-M-L-V-D-Q-T-L-F-A-P-P-F-T-M-A-M-S-F-L-V-P-L-S-N-G-E-P-I-D-R-I-R-Q-R-I-L-D-S-Y-L-S-I-L-V-R-N-Y-M-L-W-P-A-A-Q-M-L-N-F-R-F-V-P-L-G-Y-Q-V-L-Y-A-Q-F-I-A-L-V-W-N-C-Y-L-S-M-I-L-N-S"} +{"text": "### FUNCTION Required for ribosome biogenesis Part of a complex which catalyzes pseudouridylation of rRNA This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 Pseudouridine ### SEQUENCE -M-Y-L-M-Y-T-I-N-E-N-G-D-R-V-Y-T-L-K-K-R-T-E-D-G-R-P-T-L-S-A-H-P-A-R-F-S-P-E-D-K-Y-S-R-Q-R-L-T-I-K-K-R-F-G-L-L-L-T-Q-K-P-E-P-I-Y"} +{"text": "### FUNCTION Necessary for protein translocation in the endoplasmic reticulum ### SEQUENCE -M-D-K-V-V-K-F-A-E-P-G-R-A-F-A-K-D-S-I-R-L-V-K-R-C-T-K-P-D-R-K-E-F-Q-K-I-A-I-A-T-A-V-G-F-A-I-M-G-F-I-G-F-F-V-K-L-I-H-I-P-I-N-N-I-I-V-G-S"} +{"text": "### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-L-K-L-W-L-I-C-I-L-T-V-S-V-V-S-I-Q-S-L-S-L-L-E-E-T-N-Y-V-S-D-C-L-A-S-N-N-I-S-Q-A-E-F-Q-E-L-I-D-R-N-S-S-E-E-D-D-L-E-N-T-D-R-R-Y-K-C-F-I-H-C-L-A-E-K-G-N-L-L-D-T-N-G-Y-L-D-V-D-K-I-D-Q-I-E-P-V-S-D-E-L-R-E-I-L-Y-D-C-K-K-I-Y-D-E-E-E-D-H-C-E-Y-A-F-K-M-V-T-C-L-T-E-S-F-E-Q-S-D-E-V-T-E-A-G-K-N-T-N-K-L-N-E"} +{"text": "### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-L-D-Q-L-T-L-C-L-L-L-N-F-L-C-A-N-V-L-A-N-T-S-V-F-N-P-C-V-S-Q-N-E-L-S-E-Y-E-A-H-Q-V-M-E-N-W-P-V-P-P-I-D-R-A-Y-K-C-F-L-T-C-V-L-L-D-L-G-L-I-D-E-R-G-N-V-Q-I-D-K-Y-M-K-S-G-V-V-D-W-Q-W-V-A-I-E-L-V-T-C-R-I-E-F-S-D-E-R-D-L-C-E-L-S-Y-G-I-F-N-C-F-K-D-V-K-L-A-A-E-K-Y-V-S-I-S-N-A-K"} +{"text": "### FUNCTION Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB ### SEQUENCE -M-E-V-E-F-S-R-E-N-F-L-L-P-E-M-K-Y-E-Y-L-D-H-T-A-D-V-Q-I-H-G-W-G-S-S-L-K-E-A-F-E-Q-C-G-V-A-M-F-G-Y-M-T-E-L-D-Y-V-S-V-E-Q-C-F-E-I-E-A-H-G-D-D-L-E-S-L-L-F-H-F-L-D-E-L-L-F-L-F-S-A-E-P-Y-L-V-C-K-K-L-E-I-T-K-F-D-V-E-N-F-E-I-S-C-H-C-Y-G-E-P-F-E-L-G-K-H-P-Q-G-T-E-V-K-A-I-T-Y-S-A-M-Q-I-I-Q-D-V-E-A-S-N-Y-E-V-F-V-I-I-D-I"} +{"text": "### FUNCTION This protein binds cations of several transition elements Thought to be involved in metal ion homeostasis ### SEQUENCE -M-V-C-K-G-C-G-T-N-C-K-C-Q-D-T-K-C-G-D-N-C-A-C-N-Q-D-C-K-C-V-C-K-N-G-P-K-D-Q-C-C-K-S-K"} +{"text": "### FUNCTION Antiviral effector protein expressed downstream of Sting and Rel signaling in response to viral infection ### SEQUENCE -M-D-S-A-I-S-E-I-I-N-A-L-A-I-L-A-D-D-K-N-I-Q-L-T-I-K-E-A-G-K-G-A-A-I-C-A-G-A-A-L-I-G-G-L-L-L-G-P-R-G-L-A-L-G-G-A-I-G-G-L-T-A-Y-G-L-T-E-G-N-F-K-S-L-S-E-V-I-L-N-D-L-T-E-S-Q-R-R-E-L-E-Q-H-V-I-R-A-I-S-E-V-R-N-V-R-V-R-D-V-A-R-L-I-L-N-N-R-H-V-Q-E-V-A-L-E-A-V-K-S-Y-I-T-D-R-M-G-M-T-I-V-D"} +{"text": "### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs Pol II is the central component of the basal RNA polymerase II transcription machinery It is composed of mobile elements that move relative to each other RPB11 is part of the core element with the central large cleft ### SEQUENCE -M-N-A-P-P-T-F-E-S-F-L-L-Y-E-G-E-K-K-I-I-K-E-L-D-T-K-V-T-N-A-A-I-F-T-I-N-K-E-D-H-T-L-G-N-M-I-R-N-Q-L-L-K-D-P-N-V-L-F-A-G-Y-K-V-P-H-P-L-E-H-K-F-V-I-R-I-Q-T-T-A-D-Y-S-P-Q-E-A-F-M-N-A-I-T-D-L-L-A-E-L-S-L-F-E-E-R-F-K-D-A-I-K-E-K-K-E-G-G-D"} +{"text": "### FUNCTION Probably has thioredoxin reductase-like oxidoreductase activity ### SEQUENCE -M-E-R-L-T-G-R-N-V-A-L-L-V-L-C-L-C-A-G-Y-A-L-V-F-A-E-G-E-K-E-I-P-V-T-K-F-G-Q-N-I-A-P-T-M-T-F-L-Y-C-Y-S-C-G-Y-R-K-A-F-E-D-Y-V-G-L-L-G-E-K-Y-P-Q-I-Q-V-N-G-G-N-Y-D-P-P-G-L-N-Y-Y-L-S-K-M-I-F-A-L-K-I-I-I-I-V-S-V-V-S-A-V-S-P-F-T-F-L-G-L-N-T-P-S-W-W-S-H-M-Q-A-N-K-I-Y-A-C-M-M-I-F-F-L-G-N-M-L-E-A-Q-L-I-S-S-G-A-F-E-I-T-L-N-D-V-P-V-W-S-K-L-Q-T-G-R-F-P-S-P-E-V-L-F-Q-I-I-D-N-H-L-Q-F-T-E-K-V-Q-E-N-P-D-F-V-K"} +{"text": "### FUNCTION Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane ### SEQUENCE -M-A-E-Y-G-R-E-P-C-P-F-R-I-V-E-D-C-G-G-A-F-A-M-G-A-L-G-G-G-A-F-Q-A-I-K-G-F-R-N-A-P-S-G-L-G-Y-R-L-S-G-G-L-A-A-V-R-A-R-S-G-L-V-G-G-N-F-A-V-W-G-A-T-F-S-A-I-D-C-S-L-V-Y-F-R-K-K-E-D-P-W-N-A-I-I-S-G-A-T-T-G-G-I-L-A-A-R-T-G-L-T-S-M-L-S-S-A-L-V-G-G-A-L-L-A-L-I-E-G-V-G-I-V-V-S-H-Y-S-A-D-S-Y-R-Q-V-S-P-V-E-R-Q-Q-R-Y-K-Q-E-L-L-R-Q-Q-K-G-V-S-P-L-A-A-T-Y-G-E-I-D-S-S-A-L"} +{"text": "### FUNCTION Subunit of the V1 complex of vacuolar ### SEQUENCE -M-S-T-P-T-H-N-L-P-R-T-R-V-S-A-F-C-W-V-A-L-E-R-S-T-R-I-E-R-P-T-S-W-S-W-K-E-L-S-H-Y-S-L-I-V-F-H-C-I-P-D-T-T-P-K-Q-I-E-E-C-F-K-K-F-L-R-R-P-D-I-V-I-I-L-I-N-Q-V-Y-A-D-M-I-R-P-T-V-D-A-H-N-L-A-V-P-T-V-L-E-I-P-S-K-Q-H-P-Y-D-S-S-R-D-S-I-L-K-R-A-Q-R-V-I-T-P-P-E-R-H-Y"} +{"text": "### FUNCTION Required for the assembly of the V0 complex of the vacuolar ATPase in the endoplasmic reticulum ### SEQUENCE -M-S-T-K-N-K-K-A-A-G-G-N-G-V-A-P-K-Q-T-R-Q-Q-S-H-D-S-Q-D-Y-S-S-F-K-T-V-L-F-Y-C-M-L-I-V-F-L-P-V-L-T-F-F-V-L-K-G-F-V-L-D-Q-F-L-D-I-S-E-V-K-V-N-I-A-S-A-V-G-A-V-V-A-L-H-I-A-L-G-L-Y-I-Y-R-A-Y-F-G-A-P-G-S-K-G-S-K-T-D"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-I-E-T-L-Y-N-L-P-F-H-I-L-V-P-P-N-I-K-V-R-R-F-S-I-P-M-P-S-P-M-A-V-F-S-V-I-L-F-S-Y-F-L-V-T-G-G-I-I-Y-D-V-I-V-E-P-P-S-L-G-A-T-V-D-E-H-G-H-S-R-P-V-A-F-M-P-Y-R-V-N-G-Q-Y-I-M-E-G-L-A-S-S-F-L-F-T-V-G-G-L-G-F-I-I-M-D-Q-T-H-T-P-G-K-T-N-L-N-R-L-L-L-T-A-M-G-F-I-F-I-L-V-S-F-F-T-T-W-L-F-M-R-M-K-L-P-S-Y-L-Q-P"} +{"text": "### FUNCTION Mitochondrial membrane ATP synthase is coupled via a rotary mechanism of the central stalk subunits to proton translocation ATP5MK is a minor subunit of the mitochondrial membrane ATP synthase required for dimerization of the ATP synthase complex and as such regulates ATP synthesis in the mitochondria ### SEQUENCE -M-S-D-H-F-N-F-N-E-A-F-N-S-Q-T-M-R-G-R-A-N-V-A-K-A-T-W-A-S-L-G-L-V-Y-V-L-V-K-M-H-R-R-N-T-K-R-R-E-T-K-L-Y-C-K-G-C-Q-Q-A-M-L-H-G"} +{"text": "### FUNCTION Binds specifically to cytosolic chaperonin ### SEQUENCE -M-A-A-K-V-A-S-G-T-N-K-V-F-Q-N-H-D-D-V-H-I-S-F-E-D-Q-Q-R-I-N-R-F-A-K-H-N-A-R-M-D-D-F-K-A-E-L-E-T-K-R-N-E-L-K-S-L-E-E-A-L-E-E-I-E-L-F-D-E-D-E-D-I-P-F-L-V-G-E-V-F-L-S-H-K-L-E-K-T-Q-D-M-L-K-E-T-K-E-Q-V-L-K-E-I-A-G-V-E-A-K-A-K-V-I-K-A-E-M-D-E-L-K-A-H-L-Y-Q-R-F-G-S-N-I-S-L-E-A-E-D"} +{"text": "### FUNCTION Component of the signal recognition particle ### SEQUENCE -M-V-F-V-K-N-W-D-D-F-E-I-A-V-E-N-M-Y-L-A-N-P-Q-N-C-R-L-T-M-K-Y-A-H-S-K-G-H-I-L-L-K-M-T-D-N-V-K-C-V-Q-Y-K-A-E-N-M-P-D-L-R-K-I-E-K-I-T-S-N-L-V-G-H-M-A-S-K-E"} +{"text": "### FUNCTION Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner May act as a co-chaperone that stimulate the ATP-dependent activity ### SEQUENCE -M-A-S-S-V-I-L-A-G-L-S-V-A-A-V-G-F-A-G-K-H-L-M-R-R-M-P-Q-M-T-T-K-F-N-E-A-L-K-N-L-P-K-Y-D-A-E-S-M-A-A-S-K-Y-Y-K-G-G-F-D-P-K-M-N-K-R-E-A-S-L-I-L-G-V-S-P-S-A-S-K-I-K-I-K-D-A-H-K-K-I-M-L-L-N-H-P-D-R-G-G-S-P-Y-L-A-A-K-I-N-E-A-K-D-F-L-D-K-A-K"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-A-A-A-N-M-E-K-G-E-L-M-N-Q-V-K-Q-Q-I-A-L-A-N-A-Q-E-M-L-S-K-M-T-E-K-C-F-K-K-C-I-Q-K-P-G-K-S-L-D-S-T-E-Q-R-C-I-S-Q-C-M-D-R-F-M-D-A-W-N-L-V-S-R-T-Y-G-N-R-L-Q-R-E-Q-Y-R-T-M-E-S-L-E-M-T-S"} +{"text": "### FUNCTION Binds specifically to cytosolic chaperonin ### SEQUENCE -M-D-K-K-S-A-A-L-Y-K-K-M-Q-A-E-I-E-S-Y-Q-N-L-Q-K-S-C-L-K-M-V-K-Q-R-A-V-L-E-S-Q-L-N-E-N-K-C-V-L-D-E-L-N-L-L-G-P-D-N-K-V-Y-K-L-F-G-P-V-L-V-K-Q-E-L-E-E-S-R-Q-N-V-G-K-R-I-E-Y-I-S-K-E-L-K-S-S-T-D-A-L-E-N-M-E-K-D-M-L-K-H-R-E-S-V-A-K-Y-Q-Q-Q-C-Q-V-A-A-A-M-Q"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-A-K-T-P-E-N-I-A-I-D-Q-L-D-K-D-Q-I-K-T-F-S-D-F-L-M-S-Y-N-K-L-S-E-T-C-F-T-D-C-I-R-D-F-T-T-R-D-V-K-D-S-E-E-K-C-S-L-N-C-M-E-K-Y-L-K-M-N-Q-R-V-S-Q-R-F-Q-E-F-Q-V-I-A-H-E-N-A-L-A-M-A-Q-K-T-G-K-L"} +{"text": "### FUNCTION Component of the signal peptidase complex ### SEQUENCE -M-G-K-K-D-E-K-S-Q-Q-G-E-E-L-V-K-V-N-K-W-D-G-S-A-V-K-H-A-L-D-D-A-V-K-T-C-L-L-G-D-R-P-Q-L-K-E-Q-F-G-L-V-N-T-R-L-A-L-C-A-L-A-V-S-V-A-I-M-A-H-A-W-D-F-T-H-P-F-P-E-S-R-P-V-L-L-F-S-V-L-A-Y-F-A-L-L-G-I-L-T-L-H-S-S-F-R-E-K-G-T-F-A-V-A-L-Q-K-D-K-E-R-E-R-L-W-E-A-S-S-D-M-R-K-Y-D-D-K-Y-L-L-T-L-S-V-R-D-T-K-N-G-K-R-R-E-Q-S-S-N-K-S-C-A-A-F-I-D-Q-N-G-I-V-L-D-N-L-V-A-N-E-V-N-R-L-F-N-A-L-A-A-D-K-K-N-A-S-S-L-S-S-N"} +{"text": "### FUNCTION Putative gamma-glutamylcyclotransferase ### SEQUENCE -M-A-E-K-L-R-M-A-A-R-V-F-V-Y-G-T-L-K-R-G-E-P-N-H-H-W-L-T-K-K-E-N-G-Q-A-R-F-L-G-R-G-K-T-E-T-K-F-P-L-V-V-G-T-R-Y-N-I-P-F-L-L-A-R-P-G-E-G-N-H-I-E-G-E-V-Y-E-V-D-E-T-M-L-S-K-L-D-I-L-E-D-Y-P-D-Y-Y-D-R-E-Q-Q-T-I-L-M-E-Q-N-E-T-I-Q-C-W-L-Y-L-I-R-N-F-P-D-K-M-L-A-K-E-L-L-I-S-Y-H-N-T-P-E-R-P-Y-N-E-K-S-V-R-T-V-S-A-R-D-D-L-S-Y"} +{"text": "### FUNCTION May be involved in iversification of muscle cell fates ### SEQUENCE -M-L-I-A-W-L-V-L-A-A-T-L-S-R-S-I-R-A-S-T-T-I-S-I-P-I-T-T-Q-D-I-I-A-G-D-V-F-F-E-I-L-S-P-S-E-L-E-Y-T-Y-R-L-R-P-A-K-D-F-G-S-A-F-S-E-R-L-E-G-V-P-L-V-I-T-D-P-P-G-A-C-Q-E-I-R-N-A-R-D-L-N-G-G-V-A-L-I-D-R-G-E-C-S-F-L-T-K-T-L-R-A-E-A-A-G-A-L-A-A-I-I-T-E-Y-N-P-S-S-P-E-F-E-H-Y-I-E-M-I-H-D-N-S-Q-Q-D-A-N-I-P-A-G-F-L-L-G-K-N-G-V-I-I-R-S-T-L-Q-R-L-K-R-V-H-A-L-I-N-I-P-V-N-L-T-F-T-P-P-S-K-I-N-H-P-P-W-L-G-W"} +{"text": "### FUNCTION Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome ### SEQUENCE -M-G-M-V-S-K-R-K-K-M-H-Y-G-D-T-H-L-Q-R-R-W-R-V-R-N-R-R-R-D-L-D-Q-I-D-D-D-L-Q-T-R-S-G-E-L-I-N-Q-N-V-D-L-D-K-P-G-F-A-Q-F-Y-C-V-H-C-A-K-Y-F-I-D-D-T-A-M-Q-A-H-F-R-T-K-V-H-K-R-R-L-K-A-L-E-I-E-P-Y-S-I-E-E-A-E-R-A-A-G-R-G-S-F-V-K-P-K-K-R-A-M-E-T-Q-P-S-K-E-D-V-V-A-G-K-R-I-R-V-E-V-V-P-E-D-T-D-A-T-D-S-P-S-T-S-K-T-K-R-K-K-V-E-K-M-E-T"} +{"text": "### FUNCTION TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation TFIIA in a complex with TBP mediates transcriptional activity ### SEQUENCE -M-N-Y-Q-H-Y-R-A-T-T-L-G-R-T-L-Q-D-T-L-D-E-M-M-E-R-G-D-I-T-K-K-I-A-N-L-V-L-L-R-Y-D-K-S-I-S-T-A-L-K-D-H-G-T-S-N-M-S-F-T-A-E-R-L-E-T-F-R-C-C-D-N-V-W-T-L-I-L-K-D-A-E-F-R-E-D-Q-H-S-L-K-V-D-V-V-K-I-V-A-C-L-G-T-D-N-G-N-E"} +{"text": "### FUNCTION Required for the assembly of the ubiquinol-cytochrome c reductase complex May be involved in cytochrome b translation and/or stability ### SEQUENCE -M-G-F-T-G-P-L-K-Y-N-K-W-K-I-K-I-A-A-L-R-M-Y-T-C-C-V-E-R-I-D-Y-D-E-F-F-E-K-C-S-L-P-D-T-L-N-S-W-F-L-V-T-Q-L-H-V-W-M-C-L-V-R-M-K-Q-E-G-R-A-G-K-Y-M-C-R-Y-I-V-H-S-M-W-E-D-V-E-Q-R-G-K-V-M-G-I-D-S-V-T-L-K-N-S-M-R-S-M-T-E-I-F-Y-A-A-I-F-G-Y-D-E-G-I-I-S-D-D-R-I-L-A-A-A-L-W-R-N-L-L-N-K-Q-C-D-D-P-R-K-L-E-L-L-V-E-Y-V-R-K-Q-V-Q-F-L-D-T-L-D-G-E-D-L-L-L-T-G-E-V-V-W-R-P-L-V-E-K-D-A-Q-S-I-L-K-P-S-T-P-T-Y-N-D-E-G-L"} +{"text": "### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-Q-H-I-P-P-F-Y-K-T-C-A-A-G-K-N-L-C-Y-K-I-F-M-V-A-A-P-K-V-P-V-K-R-G-C-I-D-V-C-P-K-S-S-D-L-V-K-Y-V-C-C-N-T-D-R-C-N"} +{"text": "### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-K-C-N-K-L-V-P-L-F-Y-K-T-C-P-A-G-K-N-L-C-Y-K-M-F-M-V-S-N-L-T-V-P-V-K-R-G-C-I-D-V-C-P-K-S-S-L-L-V-K-Y-V-C-C-N-T-D-R-C-N"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell Required for processing of pre-rRNA and maturation of 40S ribosomal subunits ### SEQUENCE -M-N-D-T-V-T-I-R-T-R-K-F-M-T-N-R-L-L-Q-R-K-Q-M-V-V-D-V-L-H-P-G-K-A-T-V-P-K-T-E-I-R-E-K-L-A-K-M-Y-K-T-T-P-D-V-V-F-V-F-G-F-R-T-Q-F-G-G-G-K-T-T-G-F-A-M-V-Y-D-S-L-D-Y-A-K-K-N-E-P-K-H-R-L-A-T-H-G-L-Y-E-K-K-K-T-S-R-K-Q-R-T-E-R-Q-N-R-M-K-K-V-R-S-I-K-K-A-S-V-G-A-A-G-K-K-N"} +{"text": "### FUNCTION Has low cytotoxic activity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-H-N-T-Q-L-P-F-I-Y-K-T-C-P-E-G-K-N-L-C-F-K-A-T-L-R-K-F-P-L-K-F-P-V-K-R-G-C-A-D-N-C-P-K-N-S-A-L-L-K-Y-V-C-C-S-T-D-K-C-N"} +{"text": "### FUNCTION Antagonist of muscle and neuronal nicotinic acetylcholine receptors with highest affinity for neuronal alpha-7/CHRNA7 nAChRs ### SEQUENCE -M-K-T-L-L-L-T-L-A-V-V-T-M-V-C-M-D-L-G-Y-T-T-I-C-Y-N-H-L-S-R-T-P-E-T-T-E-I-C-P-D-S-W-Y-F-C-Y-K-I-S-L-A-D-G-N-D-V-R-I-K-R-G-C-T-F-T-C-P-E-L-R-P-T-G-K-Y-V-Y-C-C-R-R-D-K-C-N-Q"} +{"text": "### FUNCTION Postsynaptic neurotoxin that binds and inhibits neuronal nicotinic acetylcholine receptors Is a selective, and slowly reversible antagonist of alpha-3/CHRNA3-containing and some alpha-4/CHRNA4-containing AChRs ### SEQUENCE -M-K-T-L-L-L-S-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-T-C-H-I-S-T-S-S-T-P-Q-T-C-P-K-G-Q-D-I-C-F-R-K-T-Q-C-D-K-F-C-S-I-R-G-A-V-I-E-Q-G-C-V-A-T-C-P-E-F-R-S-N-Y-R-S-L-L-C-C-R-T-D-N-C-N-P"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-A-A-Q-V-T-E-S-D-Q-I-K-Q-F-K-E-F-L-G-T-Y-N-K-L-T-E-N-C-F-M-D-C-V-K-D-F-T-T-R-E-V-K-P-E-E-T-T-C-S-E-S-C-L-Q-K-Y-L-K-M-T-Q-R-I-S-M-R-F-Q-E-Y-H-I-Q-Q-N-E-R-W-P-Q-K-P-D-Y"} +{"text": "### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-T-C-L-N-C-P-E-M-F-C-G-K-F-Q-T-C-R-N-G-E-K-I-C-F-K-M-L-Q-Q-R-R-P-F-S-L-R-Y-I-R-G-C-A-A-T-C-P-G-T-K-P-R-D-M-V-E-C-C-N-T-D-R-C-N-R"} +{"text": "### FUNCTION Binds with high affinity to muscle nicotinic acetylcholine receptor and hinders acetylcholine binding to the receptor, thereby impairing neuromuscular transmission Causes muscle paralysis, spasms and increased respiration ### SEQUENCE -M-K-T-L-L-L-T-L-V-M-V-T-I-M-C-L-D-L-G-Y-T-L-T-C-Y-K-G-Y-H-D-T-V-V-C-K-P-H-E-T-I-C-Y-E-Y-F-I-P-A-T-H-G-N-A-I-L-A-R-G-C-G-T-S-C-P-G-G-I-R-P-V-C-C-R-T-D-L-S-N-K"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-A-Y-T-V-S-S-A-N-Q-L-V-Y-L-G-S-V-W-A-D-P-L-E-L-Q-N-L-C-T-S-A-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-S-D-V-W-K-T-I-P-T-A-T-V-R-F-P-A-T-G-F-K-V-F-R-Y-N-A-V-L-D-S-L-V-S-A-L-L-G-A-F-D-T-R-N-R-I-I-E-V-E-N-P-Q-N-P-T-T-A-E-T-L-D-A-T-K-R-V-D-D-A-T-V-A-I-R-A-S-I-S-N-L-M-N-E-L-I-R-G-T-G-M-Y-N-Q-A-L-F-E-M-A-S-G-F-T-W-A-T-I-P-Y-T"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-S-I-T-S-P-S-Q-F-V-F-L-S-S-V-W-A-D-P-I-E-L-L-N-F-G-T-N-S-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-S-E-V-W-K-P-F-P-Q-S-T-V-R-F-P-G-D-V-Y-K-V-Y-R-Y-N-A-V-L-D-P-L-I-T-A-L-L-G-S-F-D-T-R-N-R-I-I-E-V-E-N-Q-Q-N-P-T-T-A-E-T-L-D-A-T-R-R-V-D-D-A-T-V-A-I-R-S-A-I-N-N-L-V-N-E-L-V-R-G-T-G-L-Y-N-Q-N-T-F-E-S-M-S-G-L-V-W-T-S-A-P-A-S"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-A-Y-T-V-S-S-A-N-Q-L-V-Y-L-G-S-V-W-A-D-P-L-E-L-Q-N-L-C-T-S-A-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-S-D-V-W-K-T-I-P-T-A-T-V-R-F-P-A-T-G-F-K-R-F-R-Y-N-A-V-L-D-S-L-V-S-A-L-L-G-A-F-D-T-R-N-R-I-I-E-V-E-N-P-Q-N-P-T-T-A-E-T-L-D-A-T-M-R-V-D-D-A-T-V-A-I-R-A-S-I-S-P-I-M-N-E-L-V-R-G-T-G-M-Y-N-Q-A-L-F-E-S-A-S-G-L-T-W-A-T-T-P"} +{"text": "### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-N-I-T-S-S-N-Q-Y-Q-Y-F-A-A-M-W-A-E-P-Q-A-M-L-N-Q-C-V-S-A-L-S-Q-S-Y-Q-T-Q-A-A-R-D-T-V-R-Q-Q-F-S-N-L-L-S-A-I-V-T-P-N-Q-R-F-P-E-S-G-Y-R-V-Y-I-N-S-A-V-L-K-P-L-Y-E-A-L-M-K-S-F-D-T-R-N-R-I-I-E-T-E-E-E-S-R-P-S-A-S-E-V-A-N-A-T-Q-R-V-D-D-A-T-V-A-I-R-S-Q-I-Q-L-L-L-N-E-L-S-N-G-H-G-L-M-N-R-A-E-F-E-V-L-L-P-W-T-T-A-P-A-T"} +{"text": "### FUNCTION May transport viral genome to neighboring plant cells directly through plasmosdesmata, without any budding The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier ### SEQUENCE -M-A-D-T-G-Y-Y-A-G-Y-Q-D-D-V-D-V-D-E-Q-K-R-H-Q-A-L-Y-L-I-G-I-I-L-L-V-T-V-C-L-T-V-L-W-V-C-I-M-L-A-C-Y-V-P-G-F-L-K-K-T-L-E-A-W-L-N-S-S-S-L-M-K-R-R-V-A-S-T-L-T-R-T-P-F-E-A-T-G-P-E-R-E-R-N-W-E-A-R-R-Q-S-T-T-V-N-P-A-S-Q-P-N-T-G-S-V-F"} +{"text": "### FUNCTION Putative nuclear shuttle protein ### SEQUENCE -M-A-D-W-F-S-S-P-L-K-T-C-T-H-V-C-D-F-P-S-L-A-G-D-P-Q-Q-E-I-M-C-C-D-S-M-K-N-K-L-Q-D-S-R-K-V-L-L-V-S-C-S-V-S-F-N-G-S-F-Y-G-G-N-R-N-V-R-G-Q-L-Q-I-S-M-V-E-D-D-G-V-C-R-P-I-G-Y-V-P-I-G-G-Y-L-Y-H-N-D-Y-G-Y-Y-E-G-A-R-T-F-N-L-D-L-E-S-Q-Y-L-K-K-D-E-D-Y-N-R-K-F-L-V-S-V-F-N-E-N-G-L-D-S-Q-C-D-L-K-V-F-I-V-H-S-I-R-I-K-V"} +{"text": "### FUNCTION Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly ### SEQUENCE -M-T-T-I-R-G-D-D-L-S-N-Q-I-T-Q-I-S-G-S-S-S-K-K-E-E-E-K-K-K-Q-Q-M-L-T-G-V-L-G-L-Q-P-T-M-A-N-H-P-V-L-G-V-F-L-P-K-Y-A-K-Q-N-G-G-N-V-D-K-T-A-F-R-L-D-L-I-R-M-L-A-L-H-R-L-N-T-K-T-G-S-D"} +{"text": "### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase , that is believed not to be involved in catalysis Complex I functions in the transfer of electrons from NADH to the respiratory chain The immediate electron acceptor for the enzyme is believed to be ubiquinone ### SEQUENCE -M-W-F-E-I-L-P-G-L-A-V-M-G-V-C-L-V-I-P-G-V-A-T-A-Y-I-H-K-Y-T-N-G-G-K-E-K-R-V-G-R-L-R-Y-Q-W-Y-L-M-E-R-D-R-R-V-S-G-V-N-R-Y-Y-V-S-R-G-L-E-N-I-D"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-I-S-K-K-R-R-Q-E-L-I-R-K-I-I-H-E-K-K-I-S-N-Q-F-Q-I-V-E-E-L-K-K-Y-G-I-K-A-V-Q-P-T-V-A-R-D-L-K-E-I-G-A-V-K-I-M-D-E-S-G-N-Y-V-Y-K-L-L-D-E-T-P-V-I-D-P-W-K-E-L-K-R-N-F-K-S-F-V-E-S-I-D-R-A-G-N-L-I-V-I-K-T-I-P-G-T-A-S-G-I-A-R-V-I-D-R-L-D-I-D-E-I-V-G-T-L-A-G-D-D-T-I-F-V-A-V-R-D-P-E-S-C-E-K-I-V-E-K-L-S-S-I-L"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-S-I-R-P-L-Y-D-K-V-V-V-K-R-I-E-A-Q-R-T-T-A-S-G-I-V-I-P-D-T-A-S-E-K-P-E-Q-G-E-V-I-A-T-G-N-G-R-R-L-Q-D-G-T-Q-V-P-L-E-V-K-V-G-D-Q-V-L-F-G-K-Y-A-G-Q-T-V-K-L-H-G-E-E-L-L-V-L-R-E-E-D-I-L-G-V-V-E-A-S-D-A-K-L-K-K-V-A"} +{"text": "### FUNCTION Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule Could be involved in hydrogenase-linked redox processes ### SEQUENCE -M-S-E-Q-A-V-E-N-T-V-L-D-R-F-E-C-R-S-C-G-Y-V-Y-E-P-E-K-G-D-N-K-H-D-I-A-P-E-T-P-F-A-E-L-P-I-N-W-R-C-P-V-C-T-A-K-K-A-A-F-T-N-I-G-P-A-G-T-A-S-G-F-R-E-N-L-G-Y-G-L-G-V-N-K-L-T-P-A-Q-K-N-I-L-I-F-G-A-L-A-L-G-F-L-F-F-I-S-L-Y-G-L-Q"} +{"text": "### FUNCTION Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase ### SEQUENCE -M-V-Q-R-G-S-K-V-R-I-L-R-P-E-S-Y-W-F-Q-D-V-G-T-V-A-S-V-D-Q-S-G-I-K-Y-P-V-I-V-R-F-E-K-V-N-Y-S-G-I-N-T-N-N-F-A-E-D-E-L-V-E-V-E-A-P-K-A-K-P-K-K"} +{"text": "### FUNCTION Cytochrome bo ### SEQUENCE -M-A-N-A-H-D-T-H-H-E-G-N-H-G-S-V-K-S-Y-M-I-G-F-I-L-S-I-I-L-T-A-I-P-F-G-L-A-M-S-P-S-L-P-K-N-L-T-V-L-I-I-V-A-M-A-V-I-Q-V-V-V-H-L-V-Y-F-L-H-M-D-R-S-K-E-Q-R-N-N-V-W-T-F-L-F-T-T-L-V-I-A-L-L-V-G-L-S-L-W-I-M-F-S-I-H-F-E-M-L-A-K"} +{"text": "### FUNCTION Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase ### SEQUENCE -M-A-R-Y-Q-C-P-D-C-Q-Y-V-Y-D-E-S-K-G-E-E-H-E-G-F-A-P-N-T-P-W-I-V-I-P-E-D-W-C-C-P-D-C-A-V-R-D-K-L-D-F-V-L-I-E-G-S-T-G-E-K-N-I-S-S-N-N-T-L-S-V-S-A-K-V-S-S-S-D-V-N-T-E-I-S-N-T-T-M-S-A-E-I-A-L-D-V-A-T-E-G-Q-H-L-N-G-R-K-P-R-V-T-N-L-Q-S-G-A-A-F-L-K-W-I-C-I-T-C-G-H-I-Y-D-E-A-L-G-D-E-V-E-G-F-A-P-G-T-R-F-E-D-I-P-N-D-W-C-C-P-D-C-G-A-T-K-E-D-Y-V-L-Y-Q-E-K-L-G"} +{"text": "### FUNCTION Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase ### SEQUENCE -M-A-K-Y-Q-C-P-D-C-Q-Y-I-Y-D-E-C-K-G-E-P-H-E-G-F-Q-P-N-T-N-W-G-E-I-P-E-E-W-A-C-P-D-C-A-V-R-D-K-I-D-F-K-M-L-A-D-P-R-C-E-I-T-Q-L-K-Q-N-D-P-V-I-K-Q-D-N-N-I-I-E-D-T-L-S-E-P-S-I-L-S-A-E-L-E-F-T-A-E-K-I-S-I-T-D-E-R-E-N-T-P-D-N-K-V-E-R-R-S-Q-S-Q-A-V-R-R-S-S-V-K-K-I-K-N-N-K-R"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-T-L-K-E-L-Y-A-E-T-R-S-H-M-Q-K-S-L-E-V-L-E-H-N-L-A-G-L-R-T-G-R-A-N-P-A-L-L-L-H-L-K-V-E-Y-Y-G-A-H-V-P-L-N-Q-I-A-T-V-T-A-P-D-P-R-T-L-V-V-Q-S-W-D-Q-N-A-L-K-A-I-E-K-A-I-R-D-S-D-L-G-L-N-P-S-N-K-G-D-A-L-Y-I-N-I-P-P-L-T-E-E-R-R-K-D-L-V-R-A-V-R-Q-Y-A-E-E-G-R-V-A-I-R-N-I-R-R-E-A-L-D-K-L-K-K-L-A-K-E-L-H-L-S-E-D-E-T-K-R-A-E-A-E-I-Q-K-I-T-D-E-F-I-A-K-A-D-Q-L-A-E-K-K-E-Q-E-I-L-G"} +{"text": "### FUNCTION Required for bacteriochlorophyll biosynthesis Directly involved in the assembly of both the B875 and B800-850 pigment-protein complexes ### SEQUENCE -M-T-D-Q-T-S-D-V-H-M-V-R-G-H-R-P-P-K-A-E-F-M-V-Y-F-T-I-I-F-I-A-A-L-P-L-A-F-I-A-S-F-L-A-M-V-R-Q-G-D-L-K-T-K-G-P-I-A-R-A-W-S-Q-A-R-I-I-T-P-M-I-F-S-A"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-F-Q-N-Q-V-K-I-T-A-P-H-G-L-H-T-R-P-A-A-Q-F-V-K-E-A-K-K-F-T-S-E-I-S-I-I-Y-N-G-K-S-V-N-A-K-S-L-F-K-I-Q-T-L-G-L-I-Q-G-S-L-I-T-L-S-A-E-G-E-D-E-K-K-A-I-E-H-L-S-L-I-M-T-E-L-E"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-E-L-D-Y-L-T-I-A-F-G-G-A-I-G-A-V-L-R-Y-L-V-S-R-T-I-N-S-L-L-P-F-S-Y-I-P-L-G-T-I-I-V-N-S-V-G-S-F-F-L-S-F-L-M-F-A-A-I-E-K-V-P-L-S-K-E-A-I-L-F-F-G-T-G-L-L-G-A-F-T-T-F-S-T-F-T-Y-E-T-L-S-L-I-E-E-S-P-A-R-G-V-A-Y-A-L-A-N-L-L-F-A-F-T-C-A-Y-F-G-M-I-L-G-R-G-K-V"} +{"text": "### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-K-I-L-I-T-G-R-P-G-V-G-K-T-T-L-I-K-K-L-S-R-L-L-Q-N-A-G-G-F-Y-T-E-E-M-R-E-G-E-K-R-I-G-F-K-I-I-T-L-D-G-E-E-G-I-L-A-R-T-D-L-P-S-P-Y-R-V-G-K-Y-Y-V-N-L-K-D-L-E-E-I-G-V-R-S-L-E-R-A-F-Q-E-K-D-L-I-I-V-D-E-I-G-K-M-E-L-L-S-R-K-F-R-E-V-V-E-K-I-F-D-S-E-K-D-V-I-A-T-I-K-K-S-S-D-P-F-V-E-K-I-K-N-R-N-D-V-V-I-F-E-L-N-E-K-N-R-N-S-L-L-N-E-I-L-S-V-L-K-F-N-R-G-E-K-Q"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-V-Y-K-T-K-L-G-E-I-E-I-S-D-E-S-I-F-T-F-E-K-G-I-P-G-F-E-H-L-R-K-F-A-L-V-F-P-Q-E-T-F-P-I-G-W-L-L-S-L-E-D-S-E-V-G-L-P-V-V-D-P-K-L-V-R-A-D-Y-D-P-A-V-P-S-E-D-L-E-E-I-E-A-E-N-Q-E-A-L-L-F-F-C-V-L-T-I-P-P-G-K-P-E-K-T-T-I-N-L-R-A-P-I-I-L-N-Q-K-K-K-K-G-I-Q-T-I-L-E-N-E-D-Y-Q-L-R-H-L-L-S-E-E-I-E-R-S-K-T-V-V"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-K-M-K-K-Y-T-K-T-H-E-W-V-S-I-E-D-K-V-A-T-V-G-I-T-N-H-A-Q-E-Q-L-G-D-V-V-Y-V-D-L-P-E-V-G-R-E-V-K-K-G-E-V-V-A-S-I-E-S-V-K-A-A-A-D-V-Y-A-P-L-S-G-K-I-V-E-V-N-E-K-L-D-T-E-P-E-L-I-N-K-D-P-E-G-E-G-W-L-F-K-M-E-I-S-D-E-G-E-L-E-D-L-L-D-E-Q-A-Y-Q-E-F-C-A-Q-E"} +{"text": "### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-V-L-T-R-R-V-G-E-K-I-V-I-G-E-D-I-V-I-T-V-L-K-I-E-G-N-S-V-K-I-G-I-E-A-P-K-H-V-K-I-L-R-E-E-L-Y-E-E-L-K-S-E-N-I-K-A-S-E-V-S-K-D-D-L-K-G-V-L-R-N-D-K-G-Y-K-G-P-S-A-S-S"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-I-R-G-R-V-W-K-F-G-D-N-I-S-T-D-H-I-A-P-G-R-Y-F-H-L-R-N-N-L-E-E-L-A-K-H-V-L-E-D-A-M-E-D-F-A-K-K-V-Q-K-G-D-I-I-V-A-G-K-N-F-G-L-G-S-S-R-E-H-A-A-R-I-I-K-I-A-G-V-S-C-I-V-A-K-S-F-A-R-I-F-Y-R-N-A-I-N-V-G-L-P-V-I-E-L-K-E-V-D-E-I-N-Q-G-D-E-L-E-I-D-L-E-N-G-V-L-K-N-L-T-T-G-K-E-Y-R-F-T-P-I-P-K-F-L-L-E-I-L-K-E-D-G-I-V-N-Y-L-K-K-H-G-S-F-P-K-V"} +{"text": "### FUNCTION Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide ### SEQUENCE -M-P-R-V-G-I-I-M-G-S-D-S-D-L-P-V-M-K-Q-A-A-E-I-L-E-E-F-G-I-D-Y-E-I-T-I-V-S-A-H-R-T-P-D-R-M-F-E-Y-A-K-N-A-E-E-R-G-I-E-V-I-I-A-G-A-G-G-A-A-H-L-P-G-M-V-A-S-I-T-H-L-P-V-I-G-V-P-V-K-T-S-T-L-N-G-L-D-S-L-F-S-I-V-Q-M-P-G-G-V-P-V-A-T-V-A-I-N-N-A-K-N-A-G-I-L-A-A-S-I-L-G-I-K-Y-P-E-I-A-R-K-V-K-E-Y-K-E-R-M-K-R-E-V-L-E-K-A-Q-R-L-E-Q-I-G-Y-K-E-Y-L-N-Q-K-E"} +{"text": "### FUNCTION RNA chaperone that binds small regulatory RNA and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-L-A-E-K-F-N-L-Q-D-R-F-L-N-H-L-R-V-N-K-I-E-V-K-V-Y-L-V-N-G-F-Q-T-K-G-F-I-R-S-F-D-S-Y-T-V-L-L-E-S-G-N-Q-Q-S-L-I-Y-K-H-A-I-S-T-I-I-P-S-S-Y-V-M-L-M-P-K-K-Q-E-T-A-Q-E-A-E-T-S-E-N-E-G-S"} +{"text": "### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-V-V-K-I-K-G-K-V-F-V-F-G-D-N-V-N-T-D-E-I-I-P-A-R-Y-L-N-T-S-D-P-Q-E-L-A-K-Y-C-M-E-D-A-R-P-G-F-G-R-R-D-D-I-K-G-S-I-I-V-A-G-E-N-F-G-C-G-S-S-R-E-H-A-P-V-A-I-K-A-A-G-I-S-C-V-I-A-K-S-F-A-R-I-F-F-R-N-A-I-N-I-G-L-P-I-V-E-L-K-E-A-D-E-F-E-E-G-D-I-A-E-V-D-L-E-N-G-V-V-R-N-L-T-K-G-K-E-Y-R-I-R-P-Y-P-E-F-L-M-K-I-M-E-A-G-G-W-L-E-Y-C-L-K-E-V-G-E"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-Y-V-K-E-R-I-Y-E-S-M-F-I-I-A-P-N-V-P-E-E-E-R-E-N-L-V-E-R-V-K-K-I-I-E-E-R-V-K-G-K-I-D-K-V-E-R-M-G-M-R-K-F-A-Y-E-I-K-K-F-N-E-G-D-Y-T-V-I-Y-F-R-C-D-G-Q-N-L-Q-E-L-E-N-F-Y-R-V-T-P-E-I-I-R-W-Q-T-F-R-R-F-D-L-E-K-K-E-R-K-A-Q-R-E-K-A-A-A-E-A-T-E-S-S-E-G-G-S-E-D"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Y-R-R-R-K-K-K-I-K-K-C-R-L-C-E-M-K-L-D-Y-V-D-Y-K-D-T-R-L-L-S-E-F-L-T-D-K-G-K-I-I-P-K-R-L-T-G-N-C-S-K-H-Q-R-M-V-K-V-A-I-K-R-A-R-Q-M-G-L-L-P-Y-L-K-I"} +{"text": "### FUNCTION Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide ### SEQUENCE -M-K-L-S-D-F-I-K-T-E-D-F-K-K-E-K-H-V-P-V-I-E-A-P-E-K-V-K-K-D-E-K-V-Q-I-V-V-T-V-G-K-E-I-P-H-P-N-T-T-E-H-H-I-R-W-I-K-V-F-F-Q-P-D-G-D-P-Y-V-Y-E-V-G-R-Y-E-F-N-A-H-G-E-S-V-Q-G-P-N-I-G-A-V-Y-T-E-P-T-V-T-T-V-V-K-L-N-R-S-G-T-I-I-A-L-S-Y-C-N-I-H-G-L-W-E-S-S-Q-K-I-T-V-E-E"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-S-R-E-E-I-F-S-K-V-K-S-I-I-S-E-K-L-G-V-D-E-S-Q-V-T-E-E-A-K-L-I-D-D-L-G-A-D-S-L-D-L-V-D-L-V-M-D-F-E-S-E-F-G-V-K-V-D-D-A-D-L-E-K-I-S-T-V-G-D-I-V-S-Y-I-E-K-K-L-G"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-K-K-I-K-S-F-G-G-K-S-L-G-G-G-K-Q-E-K-I-L-K-D-F-A-R-M-Q-E-E-L-Q-K-K-I-Q-E-L-E-E-S-F-S-Q-I-E-V-E-A-S-V-G-G-G-A-V-R-I-V-A-T-C-D-R-R-V-K-D-I-E-I-D-E-D-L-K-E-D-F-D-T-L-K-D-L-L-I-A-G-M-N-E-V-M-E-K-I-E-K-R-R-E-E-E-M-S-K-I-T-Q-Q-F-G-I-P-G-L-M"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-V-G-V-G-I-D-V-L-E-V-E-R-V-P-E-K-F-A-E-R-I-L-G-E-S-E-K-R-L-F-L-T-R-K-R-R-R-E-F-I-A-G-R-F-A-L-K-E-A-F-F-K-A-L-G-T-G-L-N-G-H-S-F-T-D-V-E-F-L-E-S-N-G-K-P-V-L-C-V-H-K-D-F-G-F-F-N-Y-A-H-V-S-L-S-H-D-R-F-A-V-A-L-V-V-L-E-K-R-K-G-D-I-I-V-E-G-D-E-S-F-L-R-K-R-F-E-V-L-E-R-S-V-E-G-W-E-I-E-T-S-L-P-P-F-T-L-K-K-L-L-E-S-S-G-C-R-L-V-R-Y-G-N-I-L-I-G-E"} +{"text": "### FUNCTION Substrate-binding ### SEQUENCE -M-R-Q-L-I-K-A-G-I-F-T-A-L-I-V-V-G-A-W-I-S-I-P-L-G-P-V-P-F-T-L-Q-V-F-F-V-F-L-S-A-Y-V-L-G-K-K-Y-G-T-L-A-V-A-T-Y-V-L-L-G-A-M-G-L-P-V-F-A-N-F-K-G-G-A-Q-V-L-V-G-P-T-G-G-Y-L-F-G-F-I-L-G-A-F-V-I-G-L-L-A-E-K-K-E-S-F-A-W-Y-L-A-S-G-V-A-G-L-G-I-I-Y-A-L-G-V-F-V-L-N-F-Y-V-H-D-I-R-K-A-I-S-V-G-F-V-P-F-V-W-F-D-L-I-K-L-V-V-A-A-L-I-A-L-R-L-K-K-L-E-V-E-R"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-E-K-E-K-K-E-L-T-Q-E-C-E-E-L-K-E-K-Y-K-E-L-E-E-Y-A-K-R-L-K-A-E-Y-E-N-Y-R-E-E-V-A-R-E-K-R-E-L-I-K-N-A-N-E-Y-L-I-S-K-L-I-P-V-L-D-D-F-E-R-A-L-N-Q-G-E-K-G-D-A-F-Y-E-G-V-K-M-I-Y-K-K-L-L-N-V-L-E-K-E-G-L-T-K-I-H-V-G-E-K-F-D-P-F-E-H-E-A-V-E-R-V-E-T-E-D-V-E-E-Y-T-I-L-E-V-V-E-S-G-Y-K-F-H-G-K-V-L-K-P-A-K-V-K-V-A-V-K-P-R-K-K-E-E-R-K-V-E-E-P-S-D-K-K-E"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-N-P-A-Y-R-K-A-M-L-E-S-E-I-Q-K-L-L-M-E-A-L-Q-Q-L-R-D-P-R-L-K-K-D-F-V-T-F-S-R-V-E-L-S-K-D-K-R-Y-A-D-V-Y-V-S-F-L-G-T-P-E-E-R-K-E-T-V-E-I-L-N-R-A-K-G-F-F-R-T-F-I-A-K-N-L-R-L-Y-V-A-P-E-I-R-F-Y-E-D-K-G-I-E-A-S-V-K-V-H-Q-L-L-V-Q-L-G-Y-D-P-L-K-D-K-E-K-K-E-E-D-K-E-E-E"} +{"text": "### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-P-E-I-I-Y-A-A-A-P-G-A-S-N-G-T-T-T-T-A-T-G-G-G-W-G-S-L-L-F-M-L-I-F-F-I-A-I-F-Y-F-M-I-I-L-P-Q-R-R-R-E-K-Q-F-Q-Q-M-I-S-Q-M-K-R-G-D-T-V-V-T-I-G-G-I-V-G-K-V-I-D-I-K-K-D-T-V-K-I-K-T-A-N-S-T-E-L-E-I-T-K-R-A-I-S-T-V-I-K-E-R-S-Q-E-N-Q-E-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-L-R-D-V-P-K-I-G-K-K-G-E-I-K-E-V-S-D-G-Y-A-R-N-Y-L-I-P-R-G-F-A-K-E-Y-T-E-G-L-E-R-A-I-K-H-E-K-E-I-E-K-R-K-K-E-R-E-R-E-E-S-E-K-I-L-K-E-L-K-K-R-T-H-V-V-K-V-K-A-G-E-G-G-K-I-F-G-A-V-T-A-A-T-V-A-E-E-I-S-K-T-T-G-L-K-L-D-K-R-W-F-K-L-D-K-P-I-K-E-L-G-E-Y-S-L-E-V-S-L-P-G-G-V-K-D-T-I-K-I-R-V-E-R-E-E"} +{"text": "### FUNCTION Involved in resistance toward heavy metals ### SEQUENCE -M-I-L-V-Y-S-T-F-P-N-E-E-K-A-L-E-I-G-R-K-L-L-E-K-R-L-I-A-C-F-N-A-F-E-I-R-S-G-Y-W-W-K-G-E-I-V-Q-D-K-E-W-A-A-I-F-K-T-T-E-E-K-E-K-E-L-Y-E-E-L-R-K-L-H-P-Y-E-T-P-A-I-F-T-L-K-V-E-N-V-L-T-E-Y-M-N-W-L-R-E-S-V-L"} +{"text": "### FUNCTION In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts an anti-sigma factor and thus releases a sigma factor from inhibition ### SEQUENCE -M-F-P-Y-K-I-V-D-D-V-V-I-L-M-P-N-K-E-L-N-I-E-N-A-H-L-F-K-K-W-V-F-D-E-F-L-N-K-G-Y-N-K-I-F-L-V-L-S-D-V-E-S-I-D-S-F-S-L-G-V-I-V-N-I-L-K-S-I-S-S-S-G-G-F-F-A-L-V-S-P-N-E-K-V-E-R-V-L-S-L-T-N-L-D-R-I-V-K-I-Y-D-T-I-S-E-A-M-E-E-V-R-R-K"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently May also act as a chaperone or modulator of proteins involved in DNA or RNA processing ### SEQUENCE -M-R-K-P-I-E-H-T-A-D-I-A-Y-E-I-S-G-N-S-Y-E-E-L-L-E-E-A-R-N-I-L-L-E-E-E-G-I-V-L-D-T-E-E-K-E-K-M-Y-P-L-E-E-T-E-D-A-F-F-D-T-V-N-D-W-I-L-E-I-S-K-G-W-A-P-W-R-I-K-R-E-G-N-E-L-K-V-T-F-R-K-I-R-K-K-E-G-T-E-I-K-A-L-T-Y-H-L-L-K-F-E-R-D-G-D-V-L-K-T-K-V-V-F-D-T"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-V-S-L-D-P-E-K-K-N-E-I-I-K-E-F-Q-I-H-E-N-D-T-G-S-V-E-V-Q-I-A-L-L-T-A-R-I-K-H-L-T-E-H-L-R-K-H-P-K-D-F-H-S-R-R-G-L-M-K-M-I-G-R-R-R-K-M-L-K-Y-L-R-H-K-K-P-E-V-Y-R-E-L-I-A-K-L-G-I-R-K"} +{"text": "### FUNCTION A scaffold on which IscS assembles Fe-S clusters Subsequently gives the nascent cluster to other proteins It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters ### SEQUENCE -M-V-F-K-M-M-Y-S-E-A-I-L-D-Y-A-N-S-K-K-F-R-G-K-L-D-D-A-T-V-I-E-E-G-K-N-I-S-C-G-D-E-I-T-L-Y-L-K-V-E-D-G-V-V-K-D-A-K-F-E-G-M-G-C-V-I-S-Q-A-S-A-S-L-M-L-E-R-I-I-G-E-R-V-E-E-I-F-S-L-I-E-E-A-E-K-M-S-R-G-E-N-F-D-E-G-K-L-K-N-V-T-L-M-S-D-I-K-N-Y-P-A-R-V-K-C-F-I-L-A-W-K-T-L-K-E-A-L-K-K-I-S-R-P"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-V-N-P-F-I-K-E-A-K-E-K-M-K-R-T-L-E-K-I-E-D-E-L-R-K-M-R-T-G-K-P-S-P-A-I-L-E-E-I-K-V-D-Y-Y-G-V-P-T-P-V-N-Q-L-A-T-I-S-I-S-E-E-R-T-L-V-I-K-P-W-D-K-S-V-L-S-L-I-E-K-A-I-N-A-S-D-L-G-L-N-P-I-N-D-G-N-V-I-R-L-V-F-P-S-P-T-T-E-Q-R-E-K-W-V-K-K-A-K-E-I-V-E-E-G-K-I-A-I-R-N-I-R-R-E-I-L-K-K-I-K-E-D-Q-K-E-G-L-I-P-E-D-D-A-K-R-L-E-N-E-I-Q-K-L-T-D-E-F-I-E-K-L-D-E-V-F-E-I-K-K-E-E-I-M-E-F"} +{"text": "### FUNCTION In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts an anti-sigma factor and thus releases a sigma factor from inhibition ### SEQUENCE -M-N-N-L-K-L-D-I-V-E-Q-D-D-K-A-I-V-R-V-Q-G-D-I-D-A-Y-N-S-S-E-L-K-E-Q-L-R-N-F-I-S-T-T-S-K-K-K-I-V-L-D-L-S-S-V-S-Y-M-D-S-A-G-L-G-T-L-V-V-I-L-K-D-A-K-I-N-G-K-E-F-I-L-S-S-L-K-E-S-I-S-R-I-L-K-L-T-H-L-D-K-I-F-K-I-T-D-T-V-E-E-A"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-A-R-Y-F-P-V-Q-K-T-T-M-I-K-P-E-E-V-E-R-K-W-Y-V-V-D-A-S-G-K-V-L-G-R-L-A-T-R-I-A-K-I-L-M-G-K-H-K-P-N-Y-T-P-H-V-D-T-G-D-Y-V-I-V-V-N-A-D-K-V-V-L-T-G-K-K-L-D-Q-K-V-Y-Y-W-H-S-G-Y-P-G-G-L-K-S-L-T-A-R-Q-M-L-E-K-H-P-E-R-L-I-W-L-A-V-K-R-M-L-P-K-N-R-K-G-R-K-M-L-K-R-L-K-V-Y-A-S-P-E-H-P-H-Q-A-Q-K-P-E-P-I-E-L"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-L-Y-A-I-V-E-T-A-G-R-Q-Y-R-V-E-E-G-K-I-L-Y-T-E-K-Q-K-D-Y-S-P-G-D-E-I-V-F-D-R-V-V-F-V-R-K-D-G-E-V-L-V-G-K-P-Y-V-E-G-A-K-V-V-G-K-V-L-E-H-A-K-A-R-K-V-K-T-V-K-Y-R-P-R-K-N-S-K-V-E-K-G-H-R-Q-W-Y-T-A-I-K-I-E-K-I-E-L"} +{"text": "### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-I-I-R-D-V-E-L-V-K-V-A-R-T-P-G-D-Y-P-P-P-L-K-G-E-V-A-F-V-G-R-S-N-V-G-K-S-S-L-L-N-A-L-F-N-R-K-I-A-F-V-S-K-T-P-G-K-T-R-S-I-N-F-Y-L-V-N-S-K-Y-Y-F-V-D-L-P-G-Y-G-Y-A-K-V-S-K-K-E-R-M-L-W-K-R-L-V-E-D-Y-F-K-N-R-W-S-L-Q-M-V-F-L-L-V-D-G-R-I-P-P-Q-D-S-D-L-M-M-V-E-W-M-K-S-L-N-I-P-F-T-I-V-L-T-K-M-D-K-V-K-M-S-E-R-A-K-K-L-E-E-H-R-K-V-F-S-K-Y-G-E-Y-T-I-I-P-T-S-S-V-T-G-E-G-I-S-E-L-L-D-L-I-S-T-L-L-K-E-N"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-R-K-R-G-G-S-S-K-K-Q-K-K-V-S-F-D-Y-G-V-V-H-I-K-S-T-F-N-N-T-I-I-T-L-T-D-K-D-G-N-T-L-T-W-A-S-G-G-T-V-G-F-E-G-T-R-K-G-T-P-Y-A-A-Q-L-A-A-D-K-V-A-R-E-A-L-R-M-G-I-K-K-V-D-V-L-V-K-G-P-G-P-G-R-E-P-A-I-R-T-L-Q-G-A-G-L-E-I-N-Q-I-K-D-V-T-P-I-P-F-N-G-C-R-P-K-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-V-G-V-E-L-P-N-N-K-K-V-W-V-A-L-T-Y-I-Y-G-I-G-R-S-R-S-F-E-I-L-K-N-T-G-I-D-P-E-K-R-V-G-D-L-T-D-E-E-I-S-K-I-T-K-Y-I-Q-D-H-F-K-V-E-G-E-L-R-S-E-V-E-R-N-I-R-R-L-I-E-I-G-C-Y-R-G-I-R-H-K-L-G-L-P-V-R-G-Q-K-T-R-S-N-A-R-T-R-K-G-P-R-P-S-R-I-K-T-K-K-K-S-S"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-E-D-L-R-P-T-P-G-A-M-K-K-R-K-R-V-G-R-G-P-G-S-G-H-G-K-T-S-G-R-G-H-K-G-Q-K-A-R-G-S-G-K-V-H-I-W-F-E-G-G-Q-T-P-L-Q-R-R-L-P-K-R-G-F-K-N-I-N-K-K-V-Y-A-V-V-N-V-K-V-L-E-E-R-F-E-A-N-E-E-V-T-P-E-K-L-I-E-R-K-I-I-K-D-L-K-D-G-V-K-I-L-G-D-G-E-L-T-K-P-L-V-V-K-A-H-A-F-S-K-S-A-V-E-K-I-E-S-A-G-G-K-A-E-V-I"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-E-T-Q-G-V-M-K-E-I-Q-Y-E-E-F-E-E-K-I-I-E-I-R-R-T-S-K-V-T-K-G-G-K-N-L-S-F-R-V-V-A-I-V-G-N-K-N-G-K-V-G-L-G-I-G-K-A-R-E-V-P-E-A-I-R-K-A-I-S-A-A-K-R-N-I-V-E-V-P-V-I-N-G-T-I-P-H-E-V-I-G-R-Q-D-A-S-K-V-L-L-K-P-A-A-P-G-T-G-I-I-A-G-G-T-V-R-A-V-V-E-L-A-G-I-Q-N-I-L-T-K-S-L-G-S-T-N-P-L-N-L-A-L-A-T-M-N-G-L-K-N-L-L-D-P-R-K-V-A-K-L-R-D-I-S-V-E-E-V-F-K-G-V-R-R-E-N-N-A"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-R-I-L-G-E-G-K-G-S-K-L-L-E-N-L-K-E-K-L-E-E-I-V-K-K-E-I-G-D-V-H-V-N-V-I-L-V-S-E-D-E-I-K-E-L-N-Q-Q-F-R-G-Q-D-R-P-T-D-V-L-T-F-P-L-M-E-E-D-V-Y-G-E-I-Y-V-C-P-L-I-V-E-E-N-A-R-E-F-N-N-T-F-E-K-E-L-L-E-V-V-I-H-G-I-L-H-L-A-G-Y-D-H-E-F-E-D-K-N-S-K-E-M-F-E-K-Q-K-K-Y-V-E-E-V-W-G-E-W-R-S-N-P-S-E-D-S-D-P-G-K-R"} +{"text": "### FUNCTION Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation ### SEQUENCE -M-R-R-I-S-I-V-L-L-I-V-F-A-T-S-I-F-P-F-S-I-W-N-S-A-G-E-S-E-Y-K-N-L-L-S-I-K-K-A-S-K-V-G-D-I-L-T-I-V-I-R-E-S-N-N-V-S-S-E-R-E-S-L-E-I-Q-K-T-L-L-N-I-L-G-N-V-V-N-A-A-A-G-V-N-L-N-N-F-I-P-I-N-N-N-S-P-E-R-Q-R-G-G-K-V-Q-S-S-V-V-A-K-I-S-A-V-V-V-D-I-D-P-Y-G-N-L-V-V-E-G-R-K-T-I-K-V-D-K-D-Y-Q-E-I-I-V-K-G-K-V-R-P-D-D-I-E-I-G-N-E-V-D-S-S-K-L-A-D-S-E-I-W-V-N-G-K-L-V-F-S-E-E-P-G-K-E-S-F-F-D-K-I-L-A-F-L-A-G-L-F-T"} +{"text": "### FUNCTION A probable RNA chaperone Forms a complex with KhpB which binds to cellular RNA and controls its expression Plays a role in peptidoglycan homeostasis and cell length regulation ### SEQUENCE -M-K-E-L-L-E-K-I-L-R-G-I-V-K-H-P-E-E-V-V-V-M-E-F-D-E-E-G-K-K-V-Y-E-I-V-V-N-E-E-D-V-G-Q-V-I-G-K-D-G-R-T-I-K-S-L-K-I-L-L-S-A-L-M-G-D-S-K-E-I-T-I-K-V-V-R"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-I-R-T-I-Q-D-L-L-N-E-R-V-A-I-G-K-I-V-N-T-H-G-L-K-G-E-V-K-F-F-P-Y-T-N-S-E-E-I-V-K-N-L-S-S-V-V-L-Y-N-S-E-K-K-A-F-Y-N-L-T-V-E-S-V-R-R-M-N-K-L-F-L-I-R-F-K-S-I-D-T-I-E-A-A-E-R-I-K-G-C-E-V-F-I-K-Y-E-E-L-P-K-L-S-E-D-E-Y-Y-F-Y-E-I-L-D-C-D-V-F-Y-E-S-G-E-N-V-G-K-V-V-D-I-I-E-T-G-S-N-D-V-L-V-V-R-K-K-K-K-E-T-L-I-P-M-T-K-D-C-I-V-E-I-D-K-G-A-K-K-I-I-A-K-E-M-E-W-I"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-D-H-L-V-K-I-I-E-K-K-Y-E-K-K-E-I-P-D-F-R-P-G-D-T-V-R-V-H-V-K-V-I-E-G-D-R-E-R-T-Q-V-F-E-G-I-V-I-A-K-R-G-S-G-I-N-K-T-F-T-V-R-R-I-G-S-H-G-V-G-V-E-R-I-F-P-V-H-S-P-V-V-E-K-I-E-V-V-R-K-G-K-V-R-R-A-K-L-Y-Y-L-R-N-V-R-G-K-I-R-I-K-E-R-R-D"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-G-I-G-V-N-T-D-L-P-R-N-E-Q-I-K-A-P-K-V-R-V-V-D-E-N-G-K-M-I-G-V-M-P-T-R-K-A-L-E-L-A-R-E-K-G-L-D-L-V-L-V-A-P-N-E-N-P-P-V-A-R-I-M-D-Y-G-K-Y-K-Y-Q-L-T-K-K-Q-K-E-N-K-K-K-P-V-Q-M-K-Q-M-K-F-R-L-K-I-D-E-H-D-Y-Q-T-K-V-K-H-I-R-R-F-L-E-D-G-H-K-V-R-V-V-V-M-F-I-G-R-E-M-M-F-A-E-K-G-K-E-I-L-E-R-V-I-K-D-T-E-D-L-A-T-V-E-S-P-P-K-M-E-G-R-D-M-W-M-V-L-K-P-K-N-S"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-R-V-K-R-A-V-H-A-K-K-K-R-K-K-Y-L-K-A-A-K-G-Y-R-G-A-L-S-R-R-Y-K-L-A-K-Q-M-Y-V-R-S-K-W-Y-S-Y-V-G-R-K-Q-K-K-R-D-M-R-K-L-W-I-T-R-I-N-I-A-A-R-N-E-G-L-K-Y-S-E-L-I-H-G-L-K-L-A-G-V-S-I-N-R-K-M-L-S-E-L-A-V-N-D-P-E-A-F-K-E-Y-V-K-I-A-K-E-A-L-A-S"} +{"text": "### FUNCTION Associates with the EF-TuGDP complex and induces the exchange of GDP to GTP It remains bound to the aminoacyl-tRNAEF-TuGTP complex up to the GTP hydrolysis stage on the ribosome ### SEQUENCE -M-E-I-S-M-D-L-I-K-K-L-R-E-M-T-G-A-G-I-L-D-C-K-K-A-L-E-E-A-N-G-D-M-E-K-A-V-E-I-L-R-K-K-G-A-A-T-A-E-K-K-A-G-R-T-T-K-E-G-I-I-V-A-Y-V-H-F-N-G-R-I-G-V-L-L-E-M-N-C-E-T-D-F-V-A-R-T-D-E-F-K-E-L-A-Y-N-L-A-K-Q-V-A-A-M-K-P-L-Y-V-R-R-E-D-V-P-A-E-V-I-E-K-E-K-E-I-Y-R-A-Q-I-K-D-K-P-E-N-I-V-E-K-I-V-E-G-K-L-E-K-F-F-E-Q-A-C-L-Y-E-Q-T-Y-I-F-D-D-T-K-K-V-K-D-L-I-N-E-L-I-A-K-T-G-E-N-I-R-V-S-R-F-T-R-Y-E-I-G-E-G-Y-E-D"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-R-F-S-A-V-A-G-R-Y-A-R-A-L-L-N-V-A-I-E-K-E-K-E-E-E-Y-L-R-F-L-D-L-V-C-Q-I-Y-E-S-S-R-E-L-F-D-N-P-I-L-K-P-E-K-K-I-S-L-I-K-E-I-M-K-S-F-G-Q-E-M-D-E-F-Q-E-R-F-L-T-L-V-F-E-R-K-R-Q-K-L-L-R-N-I-R-D-L-F-E-Y-E-K-I-L-S-E-Q-K-V-P-A-N-L-S-I-A-H-S-P-E-D-E-E-L-S-L-L-R-K-F-V-R-K-Y-A-L-K-D-P-V-F-D-I-S-I-D-E-S-L-I-A-G-A-L-V-E-F-E-G-F-R-L-D-T-T-V-Q-G-R-L-K-R-I-A-R-E-A-L-K-R-G-E-M-S"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-G-F-L-E-I-N-W-T-S-A-A-M-L-M-L-F-V-L-M-V-Y-F-L-N-K-F-L-Y-T-P-F-I-E-M-A-E-K-R-R-K-K-V-E-E-D-L-K-S-A-E-Q-L-K-E-E-A-E-K-M-R-S-E-A-E-R-F-L-S-E-A-R-Q-R-A-D-E-I-V-E-S-A-R-K-E-A-E-A-I-V-E-E-A-R-E-K-A-K-K-E-A-Q-N-I-V-E-S-A-K-T-Q-I-E-V-E-Y-K-K-A-L-E-Q-V-Q-E-R-A-A-E-L-S-V-I-L-A-T-K-L-L-Q-K-V-F-Q-D-E-R-A-R-R-E-Y-L-V-K-I-L-K-E-E-I-E-K-S"} +{"text": "### FUNCTION Involved in restoring normal CheY-P levels by dephosphorylating CheY-P It has a greater activity than CheC ### SEQUENCE -M-D-A-R-I-V-N-A-L-I-G-S-V-Y-E-T-I-R-D-V-L-G-I-E-P-K-T-G-K-P-S-T-V-S-H-I-E-I-P-H-S-L-V-T-V-I-G-I-T-G-G-I-E-G-S-L-I-Y-S-F-S-S-E-T-A-L-K-V-V-S-A-M-M-G-G-M-E-Y-N-Q-L-D-E-L-A-L-S-A-I-G-E-L-G-N-M-T-A-G-K-L-A-M-K-L-E-H-L-G-K-H-V-D-I-T-P-P-T-V-V-S-G-R-D-L-K-I-K-S-F-G-V-I-L-K-L-P-I-S-V-F-S-E-E-D-F-D-L-H-L-S-V-K-S-G-G"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-V-V-G-L-G-N-P-G-P-R-Y-A-F-T-R-H-N-V-G-F-L-F-L-D-F-L-K-N-K-D-W-K-T-E-K-Y-F-A-W-N-K-I-N-L-A-G-N-E-V-A-L-V-K-P-L-T-Y-M-N-L-S-G-L-A-M-P-H-V-L-K-F-F-S-A-S-L-D-D-I-I-V-V-Y-D-D-V-S-L-K-L-G-K-I-R-I-R-K-K-G-S-D-G-G-H-N-G-M-K-S-I-I-Q-A-L-G-T-Q-E-I-K-R-I-R-V-G-I-G-D-K-P-E-G-M-D-L-V-N-F-V-L-G-E-F-S-D-E-E-W-I-I-L-N-K-V-F-E-V-M-K-E-A-L-E-V-I-L-V-E-G-I-E-K-A-M-S-I-Y-N-S-L-E-V-R-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-N-I-K-S-A-K-K-R-V-R-V-S-E-K-R-R-L-R-N-K-A-Y-K-T-F-F-K-N-R-I-K-E-V-L-K-A-I-E-N-K-E-P-K-E-V-V-L-E-L-T-R-K-A-Q-A-A-I-D-K-A-V-S-K-G-V-I-H-K-N-Q-G-A-R-R-K-A-R-L-F-E-K-V-N-E-Y-L-R-T-L-E-T-T-Q-E"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-E-K-I-V-K-F-D-L-K-Y-D-E-L-L-K-K-I-P-Y-K-Y-A-I-P-V-V-V-A-K-R-A-E-A-I-R-E-Y-A-R-P-F-V-I-T-D-D-E-N-Y-V-S-I-A-F-M-E-L-S-L-N-Y-I-R-I-K-N-E-E-I-L-K-A-L-I-P-K-V-K"} +{"text": "### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-K-K-V-R-L-T-R-E-G-Y-E-K-L-K-K-E-L-E-D-L-K-R-K-F-M-Y-E-I-S-E-R-I-K-E-A-R-E-L-G-D-L-S-E-N-S-E-Y-E-A-A-K-N-E-Q-G-R-V-G-S-R-I-M-E-I-E-Q-I-L-S-N-A-E-I-I-E-D-S-E-E-S-D-E-V-T-L-G-K-W-V-V-I-K-N-L-D-T-G-E-E-H-K-F-R-I-V-T-P-Q-E-A-D-F-F-A-Q-K-L-S-S-D-S-P-L-G-K-S-L-L-G-R-K-V-G-D-V-V-K-V-K-A-P-S-G-V-Q-R-Y-Q-V-I-A-V-M-N-K"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-F-C-G-S-M-D-T-R-V-L-D-S-R-P-T-L-D-G-T-A-I-R-R-R-R-E-C-S-S-C-G-K-R-F-T-T-Y-E-R-Y-E-E-A-P-V-L-V-V-K-K-D-G-R-R-E-K-F-D-R-E-K-I-K-N-G-M-I-K-A-C-E-K-R-P-V-T-Y-E-Q-I-E-E-A-V-N-R-I-C-L-K-L-R-E-E-G-S-F-E-V-E-T-K-R-I-G-E-L-V-M-E-E-L-K-K-L-D-Q-V-A-Y-V-R-L-A-S-V-Y-R-D-F-R-E-V-D-Q-F-L-E-I-V-K-E-L-K-R-E-K-E-G-E-E-Q"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-E-V-G-D-L-K-K-G-M-F-I-I-Y-D-G-E-I-Y-R-V-L-E-A-S-K-H-F-M-G-R-G-S-G-L-I-R-T-K-L-K-N-V-K-T-G-F-V-R-E-V-N-F-P-S-G-E-K-V-Q-E-A-E-L-S-F-R-K-A-Q-Y-L-Y-R-D-G-D-H-Y-Y-F-M-T-L-D-D-Y-E-Q-Y-A-L-S-E-E-E-I-G-D-A-K-Y-Y-L-V-E-N-M-E-V-D-L-V-F-H-E-G-T-P-I-G-I-E-L-P-T-T-V-E-L-T-V-V-E-T-E-P-S-F-K-G-D-T-V-S-G-G-G-K-P-A-V-L-E-T-G-L-K-I-T-V-P-Y-F-I-E-V-G-D-K-I-K-V-D-T-R-T-G-E-Y-V-G-R-A"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-K-T-P-R-R-R-M-R-L-A-V-F-K-A-L-F-Q-H-E-F-R-R-D-E-D-L-E-Q-I-L-E-E-I-L-D-E-T-Y-D-K-K-A-K-E-D-A-R-R-Y-I-R-G-I-K-E-N-L-S-M-I-D-D-L-I-S-R-Y-L-E-K-W-S-L-N-R-L-S-V-V-D-R-N-V-L-R-L-A-T-Y-E-L-L-F-E-K-D-I-P-I-E-V-T-I-D-E-A-I-E-I-A-K-R-Y-G-T-E-N-S-G-K-F-V-N-G-I-L-D-R-I-A-K-E-H-A-P-K-E-K-F-E-L"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-N-F-E-E-M-M-K-E-L-E-E-I-V-N-R-L-E-N-E-D-L-P-L-E-E-S-I-K-L-F-E-R-G-V-E-L-Y-R-K-C-K-E-I-L-Q-Q-N-R-L-K-I-I-D-V-M-K-E-L-E-G-E-I-D-A-S-G-R-D-Q-E-N-E-L-R"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-F-E-E-M-I-L-E-K-V-R-K-E-A-E-R-I-A-E-E-Q-G-L-E-I-F-D-V-Q-Y-R-R-E-S-R-G-W-V-L-R-I-I-I-D-N-P-V-G-Y-V-S-V-R-D-C-E-L-F-S-R-E-M-E-R-F-L-D-R-E-D-F-I-E-H-S-Y-T-L-E-V-S-S-P-G-L-D-R-P-L-R-G-P-R-D-Y-V-R-F-T-G-K-L-A-K-I-V-T-K-D-G-K-T-F-I-G-R-I-E-S-F-V-D-G-T-I-T-I-S-D-E-K-R-K-Y-E-I-N-I-D-D-V-K-R-A-N-L-E-V-E-F"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-V-V-Q-G-D-Y-R-G-E-G-L-K-I-A-V-V-V-P-R-F-N-D-L-V-T-S-K-L-L-E-G-A-L-D-G-L-K-R-H-G-V-S-D-E-N-I-T-V-V-R-I-P-G-S-M-E-A-I-Y-T-L-K-R-L-L-D-L-G-V-H-D-A-I-I-V-L-G-A-V-I-R-G-E-T-Y-H-F-N-V-V-A-N-E-I-G-K-A-V-A-Q-F-N-M-T-S-D-I-P-I-V-F-G-V-L-T-T-D-T-L-E-Q-A-L-N-R-A-G-A-K-S-G-N-K-G-F-E-A-A-M-V-A-I-E-M-A-N-L-R-K-R-L-R-R-D-V-F-E-S-D-S-N-G-R"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-D-Y-Y-Q-W-R-K-K-N-R-G-K-K-R-N-L-Q-A-K-K-P-L-N-Y-A-L-R-L-L-K-Y-R-V-R-F-E-D-E-L-R-E-R-L-K-K-Q-G-F-A-D-E-E-V-E-S-T-I-T-T-L-K-K-Q-G-Y-L-D-D-E-K-A-A-Y-L-F-A-L-D-E-M-R-L-K-L-F-G-P-R-V-V-K-M-K-L-K-S-L-G-V-D-E-E-I-I-E-R-A-I-E-K-A-L-E-E-I-D-F-H-E-E-L-K-R-L-K-G-R-F-K-D-R-W-E-L-R-D-Y-L-Y-R-R-G-F-D-S-S-L-I-E-E-I-L-N-K-I-D-G-G-E-E"} +{"text": "### FUNCTION Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester ### SEQUENCE -M-R-T-F-I-A-I-D-V-N-E-E-V-K-K-Q-A-S-E-I-I-E-K-L-M-K-R-G-F-G-A-T-W-V-S-E-E-N-M-H-L-T-L-F-F-L-G-E-V-D-E-Q-K-I-S-E-I-A-E-H-L-C-R-R-V-R-G-F-P-S-F-S-F-T-V-K-G-F-G-Y-F-K-R-K-M-S-P-R-V-F-W-L-G-V-E-N-T-D-R-L-M-K-L-Y-E-E-L-R-N-E-L-S-H-H-G-F-S-F-E-E-K-F-V-P-H-I-T-I-G-R-V-K-Y-Y-P-D-K-W-E-K-L-I-E-D-I-D-F-P-P-I-E-V-A-V-D-R-F-K-I-Y-S-S-T-L-T-P-T-G-P-I-Y-K-V-L-Y-E-C-Q-F-E-G-G-L-I-R-Y-A"} +{"text": "### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-E-F-R-E-Q-V-L-D-L-L-T-E-V-A-E-N-N-V-I-K-E-N-P-D-V-E-L-F-E-E-G-I-F-D-S-F-Q-T-V-G-L-L-L-E-I-Q-N-K-L-D-I-E-V-S-I-M-D-F-D-R-D-E-W-A-T-P-N-K-I-V-E-V-L-E-E-L-R"} +{"text": "### FUNCTION Multidrug exporter Is implicated for the resistance to bacteriocidal quaternary ammonium compounds ### SEQUENCE -M-K-N-W-I-F-L-A-V-S-I-F-G-E-V-I-A-T-S-A-L-K-S-S-H-G-F-T-R-L-V-P-S-V-V-V-V-A-G-Y-G-L-A-F-Y-F-L-S-L-A-L-K-S-I-P-V-G-I-A-Y-A-V-W-A-G-L-G-I-V-L-V-A-A-I-A-W-I-F-H-G-Q-K-L-D-F-W-A-F-I-G-M-G-L-I-V-S-G-V-A-V-L-N-L-L-S-K-V-S-A-H"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-S-E-H-I-V-N-V-T-D-A-S-F-E-Q-D-V-L-K-A-D-G-P-V-L-V-D-Y-W-A-E-W-C-G-P-C-K-M-I-A-P-V-L-D-E-V-A-R-D-Y-Q-G-K-L-K-V-C-K-L-N-I-D-E-N-Q-D-T-P-P-K-Y-G-V-R-G-I-P-T-L-M-L-F-K-D-G-N-V-E-A-T-K-V-G-A-L-S-K-S-Q-L-A-A-F-L-D-A-N-I"} +{"text": "### FUNCTION Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein ### SEQUENCE -M-S-I-P-T-V-K-A-K-L-L-Q-G-R-K-G-L-I-V-G-I-A-N-D-R-S-I-A-W-G-R-A-R-A-F-R-A-L-G-A-E-I-A-V-T-Y-L-N-D-K-A-L-P-L-V"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-I-I-S-D-N-K-R-G-M-H-N-Y-K-V-I-D-K-Y-E-A-G-I-S-L-M-G-W-E-V-K-S-A-R-A-N-T-V-S-L-L-N-S-Y-C-F-F-R-K-G-E-I-F-L-C-N-A-Q-F-K-Q-Y-M-L-V-K-C-D-E-T-R-D-R-K-L-L-M-H-K-N-E-I-V-R-L-Q-S-K-L-H-K-L-G-H-A-T-I-I-P-S-K-I-Y-F-D-N-R-S-R-I-K-I-E-I-A-L-V-Q-G-M-K-K-T-D-K-R-E-E-I-K-K-R-D-N-E-R-Y-I-K-K-V-L-K-N-V-Y"} +{"text": "### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-D-I-D-Q-I-P-L-T-F-T-D-A-A-A-K-K-V-K-S-L-I-E-G-E-D-N-P-N-L-R-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-D-K-I-N-E-G-D-L-T-I-E-N-Q-N-V-G-L-I-V-D-P-M-S-L-Q-Y-L-I-G-G-S-V-D-Y-T-E-G-L-D-G-S-R-F-V-V-Q-N-P-N-A-S-S-T-C-G-C-G-S-S-F-S-I"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-S-D-G-F-R-P-N-V-G-I-I-L-A-N-E-A-G-Q-V-L-W-A-R-R-I-N-Q-E-A-W-Q-F-P-Q-G-G-I-N-D-R-E-T-P-E-E-A-L-Y-R-E-L-N-E-E-V-G-L-E-A-G-D-V-R-I-L-A-C-T-R-G-W-L-R-Y-R-L-P-Q-R-L-V-R-T-H-S-Q-P-L-C-I-G-Q-K-Q-K-W-F-L-L-R-L-M-S-D-E-A-R-V-R-M-D-I-T-S-K-P-E-F-D-G-W-R-W-V-S-Y-W-Y-P-L-G-Q-V-V-T-F-K-R-E-V-Y-R-R-A-L-K-E-L-A-P-R-L-L-A-R-D"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -I-I-A-G-T-A-R-S-M-G-I-T-V-E-G"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-V-L-T-E-V-Y-R-N-V-D-D-I-P-N-I-G-S-Y-H-I-E-T-A-M-V-K-S-D-D-L-M-K-N-I-L-R-V-K-T-D-H-G-N-E-Y-G-I-R-L-D-N-E-D-Q-I-L-E-N-G-S-A-F-K-L-G-D-K-Q-L-L-V-L-S-V-I-A-D-E-M-I-E-I-T-P-R-D-I-N-E-M-G-L-V-A-H-F-L-G-N-L-H-K-P-V-Q-I-K-D-G-K-I-S-L-L-L-D-K-V-V-I-K-M-L-D-K-H-D-I-N-Y-E-L-K-K-V-Q-L-D-Q-P-L-E-Y-L-D-L-T-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-A-Y-N-K-A-D-L-E-R-R-M-K-G-A-V-E-S-L-K-S-D-F-S-G-L-R-T-G-R-A-S-T-S-L-L-D-P-V-T-V-D-V-Y-G-A-N-M-P-L-N-Q-V-A-T-V-S-V-P-E-P-R-M-I-T-V-Q-V-W-D-K-S-N-V-T-P-V-D-K-A-I-R-S-A-G-L-G-L-N-P-V-V-D-G-Q-M-L-R-L-P-I-P-D-L-T-E-E-R-R-K-E-L-A-K-L-V-G-Q-Y-S-E-K-A-R-I-A-V-R-N-V-R-R-D-G-N-D-Q-I-K-Q-D-E-K-K-N-E-I-S-E-D-E-K-K-R-F-E-N-E-V-Q-K-L-T-D-K-T-I-A-D-I-D-A-L-A-V-H-K-E-K-E-I-L-G-K"} +{"text": "### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-V-D-V-S-D-K-V-E-T-K-R-T-A-V-A-E-G-R-V-V-M-R-P-E-T-L-A-L-V-I-A-G-R-A-G-K-G-D-V-L-G-I-A-R-V-A-G-I-M-A-A-K-R-T-A-D-P-K-N-S-K-S-F-S-R-V-L-L-E-R-P-R-A-H-S-I"} +{"text": "### FUNCTION Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-G-N-M-G-T-S-E-L-L-K-H-I-Y-D-I-N-L-S-Y-L-L-L-A-Q-R-L-I-N-D-E-K-A-F-C-K-V-F-V-G-G-I-Q-G-K-G-G-A-G-Y-L-D-A-T-G-L-L-P-Q-M-V-K-L-A-E-T-N-Q-L-I-C-H-F-R-F-R-R-I-T-I-T-I-Q-S-L-D-S-G-N-Q-R-V-D-D-L-Q-Q-I-H-T-G-I-L-L-S-S-N-L-L-Q-Q-L-T-S-K-E-E-N-L-P-K-K-R-A"} +{"text": "### FUNCTION Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-A-E-K-S-I-V-Q-E-A-K-D-I-Q-L-A-M-E-L-I-S-L-G-A-R-L-Q-M-L-E-S-E-T-Q-L-S-R-G-R-L-I-K-L-Y-K-E-L-R-G-S-P-P-P-K-G-M-L-P-F-S-T-D-W-F-M-T-W-E-Q-N-I-H-S-S-M-F-Y-N-A-Y-S-F-L-I-K-N-G-Q-C-S-G-V-K-A-V-I-K-S-Y-R-L-Y-L-E-Q-C-A-P-Q-S-D-S-P-L-L-A-L-T-R-A-W-T-L-V-R-F-V-D-S-G-M-L-Q-L-S-S-C-N-C-C-K-G-M-F-I-Y-P-R-L-H-Q-P-K-N-S-F-V-C-S-L-C-Q-P-P-S-R-A-V-K-R-L-K-L-S-Q-N-L-A-D-I-I-P-R-L-L-D-E-Q-V-K-H-A-V"} +{"text": "### FUNCTION Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions, however the precise biochemical function of VdcD in metabolism of phenolic acid is unknown ### SEQUENCE -M-N-H-L-P-V-E-C-P-R-C-A-F-E-D-I-S-L-L-A-T-S-P-V-P-G-V-W-D-V-V-Q-C-G-R-C-L-Y-T-W-R-T-I-E-P-A-R-R-T-R-R-D-A-Y-P-D-S-F-K-L-T-A-E-D-I-E-N-A-I-E-V-P-A-V-P-P-L-L-K"} +{"text": "### FUNCTION Electron-transport protein of unknown function ### SEQUENCE -M-R-K-I-P-I-I-A-G-V-F-S-L-L-I-T-S-C-T-F-A-A-S-L-Q-D-D-M-N-I-L-I-A-N-L-G-I-V-S-S-S-T-D-T-K-V-I-T-S-S-L-E-K-M-R-N-A-A-L-D-A-Q-K-A-I-P-P-K-L-E-G-K-A-E-D-S-P-E-I-K-D-Y-R-H-G-F-D-L-L-I-E-Q-I-D-K-T-K-Q-W-A-E-E-G-N-I-Q-E-V-K-K-S-V-G-E-V-I-N-I-R-N-T-Y-H-S-R-Y-R"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-I-I-K-R-D-M-R-Q-D-K-R-A-A-P-K-A-P-I-N-E-N-I-S-A-R-E-V-R-L-I-G-A-D-G-E-Q-I-G-I-V-S-I-D-E-A-L-R-I-A-E-E-A-K-L-D-L-V-E-I-S-A-D-A-V-P-P-V-C-R-V-M-D-Y-G-K-S-I-F-E-K-K-K-Q-I-A-A-A-K-K-N-Q-K-Q-I-Q-V-K-E-I-K-F-R-P-G-T-E-E-G-D-Y-Q-V-K-L-R-N-L-V-R-F-L-S-D-G-D-R-A-K-V-S-L-R-F-R-G-R-E-M-A-H-Q-E-L-G-M-E-L-L-K-R-V-E-A-D-L-Q-E-Y-G-S-V-E-Q-H-P-K-M-E-G-R-Q-L-I-M-V-I-A-P-K-K-K-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-K-R-H-K-K-I-L-K-L-A-K-G-Y-Y-G-A-R-S-R-V-F-R-V-A-K-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-K-K-R-Q-F-R-A-L-W-I-A-R-I-N-A-G-A-R-N-N-G-L-S-Y-S-R-L-I-A-G-L-K-K-A-S-I-E-I-D-R-K-V-L-A-D-L-A-V-N-E-K-A-A-F-A-A-I-V-E-K-A-K-A-T-L-A"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-S-L-P-N-P-A-E-L-L-P-R-M-A-S-D-L-R-A-H-L-A-E-R-G-I-E-R-P-R-F-V-G-I-H-T-G-G-I-W-V-A-E-A-L-L-R-E-L-G-N-Q-E-P-L-G-T-L-D-V-S-F-Y-R-D-D-F-T-Q-N-G-L-H-P-Q-V-R-P-S-A-L-P-F-E-I-D-G-Q-H-L-V-L-V-D-D-V-L-M-S-G-R-T-I-R-A-A-L-N-E-L-F-D-Y-G-R-P-A-S-V-T-L-V-C-L-L-D-L-N-A-R-E-L-P-I-R-P-D-V-V-G-Q-T-L-S-L-G-R-D-E-R-V-K-L-V-G-P-A-P-L-A-L-E-R-K-V-L-S-S-A-S"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-W-K-D-F-K-E-F-A-M-K-G-N-V-V-D-L-A-V-G-V-I-I-G-G-A-F-G-K-I-V-T-S-L-V-N-D-V-I-M-P-I-L-G-L-I-L-G-G-I-N-F-T-S-A-K-L-T-L-H-G-L-N-S-E-K-P-L-T-L-N-Y-G-Q-F-I-Q-N-I-L-D-F-L-I-I-S-F-S-I-F-L-F-I-R-L-I-N-R-F-K-R-K-E-E-A-V-E-E-A-K-I-P-E-I-S-R-E-E-E-L-L-G-E-I-R-D-L-L-K-E-K-N-K"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-G-N-S-F-R-S-D-R-V-A-V-E-I-Q-R-E-I-N-D-I-L-R-N-K-V-R-D-P-R-V-Q-D-V-N-I-T-D-V-Q-L-T-G-D-L-S-Q-A-T-V-Y-Y-S-L-L-S-N-L-A-S-D-N-E-K-A-A-T-A-L-K-K-A-T-G-L-F-K-S-E-L-A-K-R-M-T-I-F-K-I-P-D-L-T-F-A-K-D-E-S-V-E-Y-G-S-K-I-D-E-I-L-T-W-A"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-R-S-T-T-P-I-N-T-T-P-I-N-Q-L-G-Y-E-A-C-R-D-E-L-I-E-V-V-R-L-L-E-Q-G-G-L-N-L-D-M-S-L-K-L-W-E-R-G-E-Q-L-A-K-R-C-E-E-H-L-D-G-A-R-Q-R-V-A-D-V-L-S-A-R-Q-V-E-E-A"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-P-P-K-K-A-N-A-A-G-P-K-K-G-Q-K-T-R-K-R-E-K-K-N-I-P-Y-G-A-A-H-I-K-S-T-F-N-N-T-I-V-T-I-T-D-Q-Q-G-N-V-I-A-W-A-S-S-G-H-V-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-L-A-A-E-N-A-A-R-K-A-Q-E-H-G-V-R-K-V-D-V-F-V-M-G-P-G-S-G-R-E-T-A-I-R-S-L-Q-A-A-G-L-E-V-G-A-I-S-D-V-T-P-Q-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-L-V-G-V-D-L-P-R-D-K-R-M-E-V-A-L-T-Y-I-Y-G-I-G-R-T-R-A-N-E-I-L-E-A-T-G-I-E-R-D-L-R-T-R-D-L-T-D-D-Q-L-T-H-L-R-D-Y-I-E-A-N-L-K-V-E-G-D-L-R-R-E-V-Q-A-D-I-R-R-K-M-E-I-G-C-Y-Q-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-K-R-T-I-A-G-K-K-K-A-R"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-G-I-V-G-V-G-I-D-L-V-S-I-P-D-F-A-E-Q-V-S-Q-P-G-T-V-F-M-T-I-F-T-P-G-E-R-R-D-A-S-V-K-S-S-S-A-V-C-H-L-A-A-R-W-A-V-K-E-A-V-I-K-A-W-S-G-S-R-F-A-Q-R-P-M-L-P-E-N-I-H-R-D-I-E-V-V-N-D-M-W-G-R-P-R-V-R-L-T-G-A-I-A-K-H-L-T-D-V-T-I-H-V-S-L-T-H-E-G-D-I-A-A-A-V-V-I-L-E-V-L"} +{"text": "### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-F-K-I-F-S-T-K-W-F-R-S-A-P-V-V-A-T-I-W-I-V-I-T-A-G-I-L-V-E-W-N-R-F-V-P-D-L-L-F-H-P-G-L"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-R-N-D-D-D-Q-E-E-K-K-T-E-L-P-L-G-K-E-T-E-A-N-L-F-K-S-R-S-I-F-I-Y-G-T-I-T-Q-E-L-A-Q-K-V-C-S-Q-L-V-A-L-A-A-A-S-D-D-D-I-R-L-F-V-N-S-P-G-G-H-V-E-S-G-D-S-I-H-D-M-I-K-F-V-K-P-K-V-W-T-I-G-T-G-W-V-A-S-A-G-A-L-I-Y-V-A-A-P-K-E-Q-R-L-C-L-P-N-T-R-F-L-L-H-Q-P-S-G-G-T-R-G-M-A-S-D-I-E-I-Q-A-R-E-I-I-K-M-N-E-R-L-N-R-I-F-S-E-A-T-G-Q-P-V-D-K-I-A-K-D-T-D-R-D-Y-W-L-G-A-E-E-A-K-A-Y-G-L-V-S-R-I-V-T-S-I-A-E-I"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system An RNase ### SEQUENCE -M-S-F-V-D-G-S-V-I-V-A-I-L-N-E-E-P-G-F-E-E-L-E-K-R-L-S-D-A-D-G-K-L-C-V-S-P-L-V-R-F-E-A-V-A-A-L-T-R-L-R-I-I-A-T-K-G-K-A-D-R-S-D-L-I-G-E-A-R-E-L-V-D-S-F-I-Q-A-L-S-A-S-E-V-T-I-D-S-H-T-G-V-R-A-L-D-A-M-A-R-Y-G-K-V-A-G-H-P-A-A-L-N-L-G-D-C-F-A-Y-A-A-A-K-E-S-G-L-T-L-I-Y-K-G-N-D-F-S-Q-T-D-L-G"} +{"text": "### FUNCTION Has lost one of the conserved residue proposed to be part of the active site Therefore it could be inactive ### SEQUENCE -M-G-S-Y-T-I-P-N-V-V-E-R-T-P-Q-G-E-R-S-Y-D-V-F-S-R-L-L-S-E-R-I-I-F-L-G-T-E-I-D-D-G-V-A-N-V-V-I-A-Q-L-L-H-L-E-S-S-A-P-E-S-E-I-A-V-Y-I-N-S-P-G-G-S-F-T-S-L-M-A-I-Y-D-T-M-T-F-V-Q-A-P-I-S-T-F-C-V-G-Q-A-A-S-T-A-A-V-L-L-A-G-G-D-P-G-R-R-F-V-L-E-H-A-R-V-L-L-G-Q-P-A-S-G-G-R-Q-G-T-V-S-D-L-A-L-Q-A-K-E-M-V-R-I-R-S-Q-V-E-E-V-L-A-R-H-T-H-H-D-V-A-T-L-R-A-D-M-D-R-D-K-V-F-T-A-Q-E-A-V-A-Y-G-L-A-D-E-V-L-A-R-R-L-T-R-V"} +{"text": "### FUNCTION Part of cytochrome c oxidase, its function is unknown ### SEQUENCE -M-K-I-Q-G-K-M-F-I-W-L-S-V-F-I-L-A-V-A-V-V-Y-G-Y-W-S-K-E-P-A-G-T-T-A-L-F-L-A-F-G-L-A-I-M-I-G-F-Y-L-A-F-T-A-R-R-V-D-A-G-A-Q-D-D-M-E-A-D-V-A-D-E-A-G-E-V-G-F-F-S-P-H-S-W-Q-P-L-S-L-A-V-G-G-A-L-A-F-L-G-I-A-V-G-W-W-V-M-Y-F-S-A-P-I-L-M-V-G-L-F-G-W-V-F-E-Y-Y-R-G-E-N-R-T-Q"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-P-R-P-R-K-A-D-R-T-P-A-R-Q-R-P-N-P-L-D-R-D-G-V-T-Y-V-D-Y-K-D-T-E-L-L-R-K-F-V-S-D-R-G-K-I-R-S-R-R-V-T-R-V-T-S-Q-Q-Q-R-Q-L-A-R-A-I-K-N-A-R-E-M-A-L-L-P-Y-G-T-R"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-N-E-Q-R-R-E-I-V-A-R-Y-A-A-R-R-A-E-L-K-E-V-L-R-R-P-S-S-T-E-A-E-R-L-A-A-Q-R-E-L-R-R-Q-P-R-D-A-S-P-T-R-V-R-N-R-D-Q-I-D-G-R-P-R-G-Y-L-R-V-F-G-L-S-R-V-N-L-R-E-Q-A-H-A-G-H-L-P-G-V-R-K-S-S-W"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-V-M-V-I-L-D-P-D-L-E-E-R-S-V-S-P-L-I-E-N-F-L-S-V-V-R-D-G-G-G-K-V-E-K-V-D-T-W-G-R-R-R-L-S-Y-E-I-K-K-K-P-E-G-I-Y-S-V-I-D-L-Q-A-E-P-A-V-V-K-E-L-D-R-Q-M-N-L-N-E-S-V-L-R-T-K-V-L-R-P-E-M-H"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-I-I-L-T-H-E-V-S-G-L-G-A-A-G-D-V-V-D-V-K-D-G-Y-A-R-N-Y-L-I-P-R-K-F-A-I-R-W-T-K-G-G-E-K-D-V-E-Q-I-R-R-A-R-K-I-H-E-I-Q-T-I-E-Q-A-N-Q-V-K-A-Q-L-E-G-V-K-V-R-L-A-V-R-S-G-D-A-G-R-L-F-G-S-V-T-P-A-D-V-A-S-A-I-K-A-A-G-G-P-E-V-D-K-R-R-I-E-L-G-S-P-I-K-T-L-G-A-H-E-T-S-V-R-L-H-P-E-V-D-A-K-V-S-I-E-V-V-A-A"} +{"text": "### FUNCTION Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-S-T-V-E-L-L-K-H-I-Y-D-I-N-L-S-Y-L-L-L-A-Q-R-L-I-N-H-E-K-A-S-A-M-F-R-L-G-I-S-E-S-M-A-D-T-L-A-E-L-T-L-P-Q-L-V-K-L-A-E-T-N-Q-L-I-C-H-F-R-F-E-D-H-E-T-V-Q-Q-L-T-K-E-S-R-V-D-D-L-Q-Q-I-H-T-G-I-L-L-S-T-H-L-F-Q-Q-L-S-A-Q-D-D-T-S-I-K-K-R-A"} +{"text": "### FUNCTION Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-V-E-K-S-I-V-Q-E-A-K-D-I-Q-L-A-M-E-L-I-T-L-G-A-R-L-Q-M-L-E-S-E-T-Q-L-S-R-G-R-L-I-R-L-Y-K-E-L-R-G-S-P-P-P-K-G-M-L-P-F-S-T-D-W-F-M-T-W-E-Q-N-I-H-S-S-M-F-Y-N-A-Y-R-F-L-L-K-S-G-H-C-E-G-V-E-V-V-V-K-A-Y-R-L-Y-L-E-Q-C-P-P-G-N-N-G-D-A-P-I-L-A-L-T-R-A-W-T-L-V-R-F-V-D-S-G-M-L-Q-P-T-E-C-R-C-C-G-G-T-F-I-T-H-A-H-Q-P-V-N-S-F-V-C-S-L-C-Q-P-P-S-R-A-V-K-K-R-K-L-S-P-Q-P-A-D-T-N-S-Q-L-L-D-G-F-A-Q-K-A-M"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-I-P-G-G-G-Q-P-N-M-Q-Q-L-L-Q-Q-A-Q-K-M-Q-Q-D-L-A-K-A-Q-E-E-L-A-R-T-E-V-D-G-Q-A-G-G-G-L-V-K-A-T-V-T-G-S-G-E-L-R-G-L-V-I-D-P-K-A-V-D-P-E-D-T-E-T-L-A-D-L-V-V-A-A-V-Q-A-A-N-E-N-A-Q-N-L-Q-Q-Q-K-L-G-P-L-A-Q-G-M-G-G-G-G-S-G-I-P-G-L-P-F"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Y-E-G-V-V-Q-D-L-I-D-E-L-G-R-L-P-G-V-G-P-K-S-A-Q-R-I-A-F-H-I-L-Q-A-E-P-V-D-V-R-R-L-A-Q-A-L-M-E-V-K-A-K-V-R-F-C-A-T-C-G-N-V-A-Q-E-E-Q-C-N-I-C-R-D-T-R-R-D-P-S-V-I-C-V-V-E-E-P-K-D-V-V-A-I-E-R-T-R-E-F-R-G-R-Y-H-V-L-G-G-A-I-S-P-I-D-G-V-G-P-D-D-L-R-I-R-E-L-L-A-R-L-A-D-G-S-V-T-E-L-I-L-A-T-D-P-N-L-E-G-E-A-T-A-T-Y-L-A-R-M-I-K-P-M-G-L-K-V-T-R-L-A-S-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-G-R-A-F-E-G-R-R-L-L-D-V"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation ### SEQUENCE -M-A-N-K-Q-D-L-I-A-K-V-A-A-A-T-E-L-T-K-K-D-S-A-A-A-V-D-A-V-F-A-A-V-T-E-Y-L-S-K-G-E-K-V-Q-L-I-G-F-G-N-F-E-V-R-E-R-A-A-R-K-G-R-N-P-Q-T-G-K-E-T-K-I-A-A-S-K-V-P-A-F-K-A-G-K-A-L-K-D-A-V-K"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation ### SEQUENCE -M-A-N-K-Q-D-L-I-A-K-V-A-E-A-T-E-L-T-K-K-D-S-A-A-A-V-D-A-V-F-S-A-V-S-S-Y-L-A-K-G-E-K-V-Q-L-I-G-F-G-N-F-E-V-R-E-R-A-A-R-K-G-R-N-P-Q-T-G-E-E-I-K-I-K-A-S-K-V-P-A-F-K-A-G-K-A-L-K-D-A-V-K"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation ### SEQUENCE -M-A-N-K-Q-D-L-I-A-K-V-A-E-A-T-E-L-T-K-K-D-S-A-A-A-V-D-T-V-F-S-S-I-E-G-F-L-S-K-G-E-K-V-Q-L-I-G-F-G-N-F-E-V-R-E-R-A-A-R-K-G-R-N-P-Q-T-G-A-E-I-K-I-A-A-S-K-V-P-A-F-K-A-G-K-A-L-K-D-A-V-K"} +{"text": "### FUNCTION Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule Could be involved in hydrogenase-linked redox processes ### SEQUENCE -M-S-E-Q-A-V-E-N-T-V-L-D-R-F-E-C-R-S-C-G-Y-V-Y-E-P-E-K-G-D-S-K-H-D-I-A-P-E-T-P-F-A-E-L-P-I-N-W-R-C-P-V-C-T-A-K-K-A-A-F-S-N-I-G-P-A-G-T-A-S-G-F-R-E-N-L-G-Y-G-L-G-V-N-K-L-T-P-A-Q-K-N-I-L-I-F-G-A-L-A-L-G-F-L-F-F-I-S-L-Y-G-L-Q"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-K-V-K-I-K-P-L-S-D-R-V-V-I-K-P-E-P-P-E-E-K-T-E-S-G-L-Y-I-P-D-T-A-K-E-K-P-Q-R-G-T-V-I-A-V-G-P-G-R-V-E-N-G-T-K-I-E-M-S-V-K-E-G-D-K-V-L-Y-G-K-Y-A-G-T-E-I-T-I-D-G-E-E-Y-L-I-M-R-E-T-D-I-L-G-I-I-E-E-E-K"} +{"text": "### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-V-N-L-N-I-A-L-I-A-H-D-M-K-K-S-L-M-I-D-F-A-I-A-Y-K-D-I-L-E-K-C-N-I-Y-A-T-G-A-T-G-Q-L-V-E-E-A-T-G-I-K-V-N-K-F-L-P-G-P-M-G-G-D-Q-Q-I-G-A-M-I-A-E-D-K-M-D-L-V-I-F-L-R-D-P-L-T-A-Q-P-H-E-P-D-I-L-A-L-L-R-V-C-D-V-H-S-I-P-L-A-T-N-L-A-T-A-E-V-L-I-K-G-L-D-A-G-L-L-E-W-R-N-A-V-K"} +{"text": "### FUNCTION Catalyzes the conversion of dTDP-4-amino-4,6-dideoxy-D-glucose ### SEQUENCE -M-A-Y-L-D-E-I-Q-L-K-E-M-G-F-K-S-V-G-E-N-V-K-I-S-D-K-A-S-F-Y-G-C-D-N-I-S-I-G-N-N-V-R-I-D-D-F-C-V-F-S-A-G-E-G-G-I-D-I-H-D-Y-I-H-I-A-V-Y-S-S-I-I-G-K-G-K-V-T-I-S-D-Y-A-N-I-S-S-R-V-S-I-Y-S-S-N-E-Y-Y-S-G-N-Y-M-S-N-P-V-V-P-S-E-Y-T-N-I-H-S-G-T-V-F-I-G-K-H-V-I-I-G-C-G-S-I-V-L-P-D-V-I-L-H-E-G-A-A-I-G-A-L-S-V-V-K-E-D-C-E-A-F-T-V-N-V-G-I-P-A-K-P-I-S-E-R-S-K-K-L-L-E-L-E-S-V-F-K-P-S-A-I-G-D-N-L"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-D-D-K-K-S-V-K-K-E-K-K-V-K-K-K-E-K-K-I-V-P-R-G-K-V-Y-I-T-A-S-F-N-N-T-I-V-T-I-T-D-M-A-G-N-T-I-S-W-S-T-S-G-A-M-G-F-R-G-S-K-K-S-T-P-Y-A-A-Q-I-A-A-G-N-A-A-E-K-A-M-D-S-A-G-L-Q-E-V-D-V-M-V-S-G-P-G-I-G-R-E-S-A-I-R-S-L-V-A-R-G-L-N-I-K-M-I-K-D-V-T-P-L-P-H-N-G-C-R-P-R-K-R-R-R-V"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-D-L-P-R-E-K-R-I-V-V-G-L-T-Y-I-F-G-I-G-N-S-L-S-K-L-I-L-K-K-A-G-I-D-E-S-I-R-V-K-D-L-N-E-S-Q-E-A-A-I-R-K-T-L-E-E-T-A-K-V-E-G-D-L-R-S-E-I-Q-L-N-I-K-R-L-M-D-I-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-N-G-Q-R-T-R-T-N-A-R-T-R-K-G-G-K-K-T-V-A-N-K-K-K-V-T-K"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-A-I-T-V-D-G-T-V-L-E-P-L-P-N-A-M-F-R-V-E-L-E-N-G-H-K-V-L-A-H-I-S-G-K-M-R-M-H-Y-I-R-I-L-P-G-D-K-V-T-V-E-L-S-P-Y-D-L-S-K-G-R-I-T-Y-R-K-K"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-K-E-R-L-E-Q-A-S-A-F-G-K-D-R-V-K-K-K-K-N-T-D-T-S-S-N-L-I-P-V-P-K-G-A-T-K-E-K-K-R-V-G-R-G-P-G-S-K-V-G-K-T-A-G-R-G-S-K-G-Q-Y-A-R-N-T-V-R-R-G-F-E-G-G-Q-M-P-I-H-R-R-L-P-K-R-G-F-T-S-K-F-H-K-E-F-Y-P-V-N-L-R-D-I-E-K-S-G-L-T-G-N-I-D-A-K-I-M-V-Q-S-K-I-L-D-K-E-T-T-L-F-K-I-L-G-T-G-E-I-K-K-A-I-H-V-I-A-D-G-F-S-Q-S-A-K-E-K-I-E-K-A-G-G-S-I-K-L-R-A-E-L-K-L-A-T-S-E-T-K-K"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-Y-Q-D-E-E-S-K-E-Y-S-E-K-V-V-K-I-D-R-V-A-K-V-V-K-G-G-R-R-F-S-F-N-A-L-S-V-V-G-D-Q-R-G-K-V-G-I-G-F-G-K-A-N-E-V-P-D-A-I-R-K-S-I-E-S-A-K-K-H-L-V-K-I-N-F-K-G-H-T-I-P-H-E-V-I-G-K-F-K-S-A-R-V-I-L-K-P-S-T-A-G-T-G-I-I-A-G-A-S-V-R-S-I-V-E-K-A-G-I-Q-D-V-L-T-K-S-W-G-S-S-N-P-V-N-I-V-K-A-T-L-D-A-L-E-Q-L-E-T-P-I-L-A-A-K-K-R-G-I-S-L-N-K-L-F-G-K-D"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-D-R-L-K-K-S-I-S-K-T-K-R-A-E-R-S-R-F-K-L-K-K-L-G-S-R-P-R-L-V-F-I-K-S-N-Q-Y-L-S-C-Q-I-I-D-D-I-Q-G-V-T-L-A-Y-A-T-T-S-E-K-T-F-T-G-E-G-K-S-K-K-D-K-G-A-A-K-V-L-G-K-L-I-A-E-R-G-S-Q-K-G-V-K-Q-V-M-L-D-R-S-G-M-I-F-H-G-R-I-A-A-F-A-E-G-A-R-E-A-G-L-E-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-A-E-I-K-L-P-D-K-V-E-V-K-Q-E-N-A-N-I-K-V-K-G-P-L-G-E-L-F-T-P-I-F-E-G-I-S-V-K-T-E-N-G-I-V-K-L-E-R-S-N-E-D-Q-K-V-V-A-L-H-G-L-T-R-A-L-L-M-N-C-V-K-G-V-S-Q-G-W-E-K-N-L-E-I-T-G-V-G-Y-R-A-Q-K-R-G-E-D-L-V-M-S-L-G-F-S-H-E-V-V-Y-K-A-P-K-G-I-K-I-D-V-Q-E-Q-L-K-I-K-V-S-G-I-D-K-Q-L-V-G-Q-V-A-A-D-I-R-S-K-R-P-P-E-P-Y-K-G-K-G-I-K-Y-A-E-E-F-I-K-K-K-A-G-K-T-G-K-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-S-D-P-I-G-D-M-L-T-R-I-R-N-A-G-R-A-K-H-E-T-C-L-V-P-G-S-K-I-K-K-S-I-L-D-L-M-K-E-E-G-F-I-K-D-Y-E-S-V-K-V-N-E-T-F-E-D-Y-K-V-F-L-K-Y-D-H-T-K-R-P-I-I-R-E-L-V-R-V-S-T-P-G-R-R-V-Y-I-K-S-A-E-I-R-P-Y-K-N-N-I-G-T-L-I-V-S-T-S-K-G-I-M-T-G-K-N-A-R-K-L-K-L-G-G-E-V-I-L-K-M-S"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-S-I-T-V-R-H-Q-R-K-K-K-F-E-V-R-E-Y-N-R-C-P-I-C-G-R-S-R-G-Y-L-R-R-F-D-M-C-R-I-C-F-R-K-L-A-S-G-A-Q-I-P-G-V-V-K-S-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-A-R-L-R-T-K-Y-K-K-E-I-V-P-E-L-N-K-K-F-K-F-S-S-I-M-Q-V-P-R-L-E-K-I-V-L-N-V-G-M-G-E-A-H-T-N-P-K-A-L-E-A-A-V-E-E-L-A-L-I-T-G-Q-R-P-V-K-T-K-A-K-K-S-I-A-G-F-K-I-R-E-G-M-S-L-G-C-M-V-T-L-R-G-D-Y-M-Y-E-F-L-D-R-L-V-N-V-A-L-P-R-V-R-D-F-K-G-V-S-E-K-G-F-D-G-R-G-N-Y-N-M-S-I-K-E-Q-I-I-F-P-E-I-K-V-D-K-I-N-T-L-Y-G-I-N-M-T-F-V-T-N-S-K-S-N-E-E-A-Y-S-L-L-A-A-F-G-M-P-Y-R-N-Q-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-K-L-T-Y-R-G-S-E-Y-T-K-F-K-K-F-R-I-K-K-N-D-E-V-I-C-I-T-G-K-H-K-G-K-R-G-K-V-L-S-I-D-K-K-R-D-R-V-I-V-E-G-L-N-K-R-K-R-F-M-R-P-T-Q-E-N-P-Q-G-G-V-I-E-V-E-A-P-I-H-I-S-N-V-M-F-Y-D-P-K-K-K-K-K-A-G-V-R-V-G-F-E-T-V-K-G-K-K-V-R-V-S-R-P-D-K-K-E-L"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-L-L-Q-V-A-D-N-S-G-I-K-K-V-M-C-I-K-V-L-G-G-S-K-K-R-Y-A-S-V-G-D-E-I-I-V-A-V-K-D-A-Q-P-A-F-G-L-K-D-S-T-G-K-K-V-H-N-K-A-V-Q-R-A-V-V-V-R-T-T-K-E-I-R-R-P-D-G-S-Y-I-R-F-D-D-N-A-C-A-I-I-D-D-K-G-N-P-K-G-T-R-I-F-G-P-V-A-R-E-L-R-D-K-K-Y-A-K-I-I-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-T-A-G-K-Q-H-I-N-K-S-L-L-Y-E-G-R-V-V-S-N-S-M-N-K-T-V-V-I-L-V-E-T-R-K-T-H-P-K-F-K-K-I-V-R-R-S-V-R-L-K-V-H-D-E-K-N-E-C-V-V-G-D-K-I-L-A-I-E-T-R-P-L-S-K-E-K-R-H-R-L-Y-K-I-V-E-K-A-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-S-P-K-R-V-K-F-R-K-R-Q-R-G-R-L-K-G-T-D-E-R-G-S-S-V-S-F-G-E-F-G-L-K-A-V-T-S-G-R-L-T-A-R-Q-I-E-A-A-R-I-T-I-N-R-Q-V-K-R-G-G-K-L-W-I-R-I-F-P-H-T-P-I-T-K-K-P-A-E-T-R-M-G-K-G-K-G-N-P-E-F-W-I-A-E-I-R-P-G-R-I-L-F-E-M-S-G-I-D-E-E-T-A-K-K-A-L-S-L-A-S-Y-K-L-P-I-H-T-E-F-V-K-R-S-A-L"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-V-S-R-F-V-R-M-S-P-R-K-V-R-L-V-A-D-E-I-R-G-Y-A-V-N-E-A-L-D-I-L-K-F-T-N-K-R-A-I-E-P-L-T-K-V-I-L-S-A-S-A-N-A-S-V-L-N-N-K-V-D-F-N-Q-L-F-I-K-K-I-Y-V-D-E-G-P-I-M-K-R-F-R-P-R-A-R-G-R-A-A-R-I-R-K-R-L-S-H-I-T-V-V-L-S-D"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-V-K-K-G-P-F-I-D-D-H-L-M-K-K-I-T-K-L-N-S-E-N-Q-K-K-P-F-K-T-W-S-R-R-S-T-I-F-P-D-M-V-G-H-T-V-M-V-H-N-G-K-Q-F-T-P-V-Y-I-N-E-N-M-I-G-H-K-L-G-E-F-S-P-T-R-T-F-R-G-H-V-A-G-D-K-K-A-A-K-K"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-L-Q-D-V-I-L-T-P-I-V-T-E-K-S-Q-D-L-E-T-I-G-A-N-S-K-K-G-T-R-M-V-K-Y-T-V-K-V-H-I-D-A-N-K-T-L-I-K-E-A-F-K-K-I-F-K-V-T-P-S-S-V-N-V-Q-V-Y-R-G-K-I-K-R-F-R-N-M-P-A-A-R-P-H-W-K-K-A-I-V-T-F-R-D-G-A-S-I-D-F-A-K-E-A"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-G-Q-K-I-R-V-K-L-K-A-F-D-H-R-L-I-D-Q-S-T-Y-E-I-V-A-T-A-K-R-T-G-A-T-V-S-G-P-I-P-L-P-T-K-K-E-I-Y-T-V-L-R-S-P-H-V-N-K-K-S-R-E-Q-F-E-L-K-T-H-K-R-L-I-D-I-L-D-T-N-E-D-T-V-E-A-L-M-K-L-Q-L-P-A-G-V-S-V-D-I-K-S"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-N-A-K-T-L-D-A-I-K-P-F-L-D-W-I-P-L-I-V-F-F-Y-I-Y-K-T-T-E-G-E-G-S-E-H-I-I-A-A-T-T-G-L-L-I-A-T-L-I-V-Y-G-L-M-F-V-L-Q-K-F-T-L-E-K-R-Q-W-L-V-V-V-L-T-V-V-F-G-G-L-T-M-A-F-Q-D-D-F-Y-I-R-L-K-A-P-I-I-N-A-V-F-A-F-G-L-A-M-S-P-L-F-L-G-G-T-P-G-I-Q-K-M-L-G-P-I-F-E-M-T-P-K-Q-W-M-K-L-N-W-V-W-V-G-F-F-T-L-M-A-V-L-Q-A-L-F-A-F-V-W-V-E-Y-W-A-M-F-T-A-F-G-D-M-I-V-M-V-V-F-M-V-A-Q-F-W-F-L-R-G-F-M-R-K-D-I-K"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-L-I-V-Y-F-S-S-A-T-D-N-T-H-R-F-V-Q-K-L-D-L-P-N-V-R-I-P-L-T-R-V-E-E-P-L-K-I-N-E-P-Y-V-L-I-T-P-T-Y-G-G-G-V-S-M-T-G-E-N-S-R-P-V-P-P-Q-V-I-R-F-L-N-D-E-H-N-R-S-F-I-R-A-V-V-A-G-G-N-S-N-F-G-S-D-F-G-L-A-G-E-I-I-S-K-K-C-K-V-P-Y-V-Y-R-F-E-L-M-G-N-E-E-D-V-S-I-L-R-G-G-L-T-Q-N-A-Q-A-L-G-L-E-P-Q-E-P-V-T-S-R"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-E-F-N-R-E-A-Y-S-E-R-E-R-S-A-A-S-M-K-T-L-L-R-K-Q-E-L-V-N-S-Y-K-E-R-L-Q-R-S-N-G-F-V-V-F-F-N-F-Q-G-I-D-A-Y-P-L-T-L-L-R-L-D-I-K-D-L-K-G-E-I-V-V-G-K-N-T-L-F-Y-R-A-F-S-D-T-A-L-S-D-H-R-D-I-F-I-G-P-T-A-A-L-F-A-Y-E-D-P-V-A-V-T-K-K-L-V-E-F-L-K-E-T-F-D-K-E-W-E-G-R-I-K-G-G-L-L-D-Y-K-Y-I-S-P-E-Q-V-K-E-L-A-E-L-P-S-K-E-E-L-I-A-K-L-L-G-V-M-M-A-P-V-T-Q-L-A-M-T-L-K-A-V-P-Q-K-L-V-L-V-L-K-A-I-E-E-E-K-S-K-G-G-Q"} +{"text": "### FUNCTION Binds directly to 23S rRNA The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release ### SEQUENCE -I-L-G-P-R-G-L-M-P-S-P-K-T-G-T-V-T-K-N-V-E-Q-A-I-K-D-A-K-R-G-R-V-E-F-K-V-D-K-A-G-N-I-H-M-P-V-G-K-V-S-F-D-K-A-K-L-L-D-N-I-Y-A-A-I-D-A-V-V-R-A-K-P-P-G-A-K-G-Q-Y-V-K-N-I-A-L-S-L-T-M-S-P-S-V-K-I-D-I-N-E-T-L-R-K-L-Q-E-R-A-A"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-A-Y-V-D-D-H-L-M-C-E-V-E-G-N-P-G-Q-T-L-T-A-A-A-I-I-G-H-D-G-S-V-W-A-Q-S-S-T-F-P-Q-I-K-P-E-E-I-A-G-I-M-K-D-F-D-E-P-G-H-L-A-P-T-G-L-Y-L-G-G-A-K-Y-M-V-I-Q-G-E-P-N-A-V-I-R-G-K-K-G-S-G-G-V-T-I-K-K-T-G-Q-A-L-V-F-G-V-Y-D-E-P-V-T-P-G-Q-C-N-V-I-V-E-R-L-G-D-Y-L-I-D-Q-G-L"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-A-Y-V-D-D-H-L-M-C-D-I-D-G-H-H-L-T-A-A-A-I-L-G-H-D-G-S-V-W-A-Q-S-S-T-F-P-K-F-K-P-E-E-I-T-A-I-M-K-D-F-D-E-P-G-S-L-A-P-T-G-L-H-L-G-G-T-K-Y-M-V-I-Q-G-E-G-G-A-V-I-R-G-K-K-G-S-G-G-V-T-V-K-K-T-S-Q-A-L-V-F-G-I-Y-E-E-P-L-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-I-D-Q-G-L"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-A-Y-V-D-D-H-L-M-C-D-I-D-G-N-R-L-T-A-A-A-I-L-G-Q-D-G-S-V-W-S-Q-S-A-T-F-P-A-F-K-P-E-E-I-A-A-I-L-K-D-L-D-Q-P-G-T-L-A-P-T-G-L-F-L-G-G-T-K-Y-M-V-I-Q-G-E-A-G-A-V-I-R-G-K-K-G-S-G-G-I-T-V-K-K-T-N-Q-A-L-I-I-G-I-Y-D-E-P-L-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-I-E-Q-G-L"} +{"text": "### FUNCTION RuBisCO catalyzes two reactions the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate Both reactions occur simultaneously and in competition at the same active site Although the small subunit is not catalytic it is essential for maximal activity ### SEQUENCE -M-A-S-S-L-M-S-N-A-I-T-A-V-V-G-A-S-G-A-Q-A-N-M-V-A-P-F-N-G-L-K-S-I-A-S-F-P-V-T-R-K-S-N-D-I-T-S-I-A-S-N-G-G-R-V-Q-C-M-Q-V-W-P-P-V-G-K-K-K-F-E-T-L-S-Y-L-P-P-L-S-D-A-Q-L-L-A-Q-V-Q-Y-L-L-N-N-G-W-I-P-C-I-E-F-E-L-E-H-P-F-V-Y-R-E-N-H-R-S-P-G-Y-Q-D-G-R-Y-W-T-M-W-K-L-P-M-Y-G-C-T-D-P-A-Q-V-L-N-E-V-E-E-A-K-K-A-Y-P-S-A-F-I-R-I-I-G-F-D-N-K-R-Q-V-Q-C-V-S-F-I-A-F-K-P-P-G-Y"} +{"text": "### FUNCTION RuBisCO catalyzes two reactions the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate Both reactions occur simultaneously and in competition at the same active site Although the small subunit is not catalytic it is essential for maximal activity ### SEQUENCE -M-A-S-S-M-M-S-N-A-A-T-A-V-A-V-A-A-T-S-G-G-A-Q-A-N-M-V-A-P-F-N-G-L-K-S-I-A-S-F-P-V-T-R-K-S-N-D-I-T-S-I-A-S-N-G-G-R-V-Q-C-M-Q-V-W-P-P-V-G-K-K-K-F-E-T-L-S-Y-L-P-P-L-S-D-A-Q-L-L-A-Q-V-Q-Y-L-L-N-K-G-W-I-P-C-I-E-F-E-L-E-H-P-F-V-Y-R-E-N-H-R-S-P-G-Y-Q-D-G-R-Y-W-T-M-W-K-L-P-M-Y-G-C-T-D-P-A-Q-V-L-N-E-V-E-E-A-K-K-A-Y-P-T-A-F-I-R-I-I-G-F-D-N-K-R-Q-V-Q-C-V-S-F-I-A-Y-K-P-A-D-S-Y"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-D-K-S-M-L-G-D-L-D-G-L-P-E-E-D-K-M-R-M-A-A-M-V-D-Q-L-Q-I-R-D-S-L-R-M-Y-N-S-L-V-E-R-C-F-T-D-C-V-D-T-F-R-R-K-T-L-D-K-Q-E-E-S-C-V-R-R-C-A-E-K-F-L-K-H-S-M-R-V-G-M-R-F-A-E-L-N-Q-G-V-A-T-P-D"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-D-K-N-M-L-G-D-L-D-N-L-P-E-E-D-K-L-K-M-A-S-M-I-E-Q-L-Q-I-R-D-S-L-R-M-Y-N-N-L-V-E-R-C-F-T-D-C-V-D-S-F-R-R-K-T-L-D-K-Q-E-E-T-C-V-K-R-C-A-E-K-F-L-K-H-S-M-R-V-G-L-R-F-A-E-L-N-Q-G-A-A-T-T-D"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-D-S-F-S-S-S-S-G-S-P-P-N-T-E-A-L-M-D-Q-I-K-A-Q-L-A-Q-A-Y-A-Q-E-F-L-E-T-V-G-N-K-C-F-A-K-C-V-T-K-P-G-S-S-L-S-G-S-E-S-S-C-I-S-R-C-V-D-R-Y-I-E-A-T-G-I-V-S-R-A-L-F-S-S-T-R"} +{"text": "### FUNCTION Cytokinin-activating enzyme working in the direct activation pathway Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms ### SEQUENCE -M-H-I-E-H-I-S-G-E-T-V-G-E-V-R-I-V-S-D-M-H-E-R-K-A-T-M-A-Q-E-A-G-A-F-I-A-L-L-G-E-R-Y-E-T-M-E-E-L-L-E-M-I-T-W-A-Q-L-G-I-H-K-K-T-V-G-L-L-N-V-D-G-Y-Y-N-N-L-L-A-F-F-D-T-G-V-E-E-G-F-I-K-Q-G-A-C-N-I-V-V-S-A-P-S-A-R-E-L-M-E-K-M-E-L-Y-T-P-S-H-K-Y-I-A-S-H-Q-S-W-K-V-E-P-L-G-D-Y-P-L-L-N-E-N-K-P-Q"} +{"text": "### FUNCTION May form complexes with phosphorylated ligands by interfering with kinases and their effectors ### SEQUENCE -M-G-S-K-M-S-D-P-L-V-I-G-R-V-I-G-E-V-V-D-Y-F-T-P-S-V-K-M-S-V-T-Y-N-S-S-K-H-V-Y-N-G-H-E-L-F-P-S-S-V-T-S-K-P-R-V-E-V-H-G-G-D-L-R-S-F-F-T-L-I-M-I-D-P-D-V-P-G-P-S-D-P-Y-L-R-E-H-L-H-W-I-V-T-D-I-P-G-T-T-D-C-S-F-G-R-E-I-V-G-Y-E-M-P-R-P-N-I-G-I-H-R-F-V-F-L-L-F-K-Q-K-K-R-Q-T-L-L-S-A-P-L-S-R-D-R-F-N-T-R-K-F-S-E-E-N-E-L-G-S-P-V-A-A-A-F-F-N-C-Q-R-E-T-A-A-R-R-R"} +{"text": "### FUNCTION May form complexes with phosphorylated ligands by interfering with kinases and their effectors ### SEQUENCE -M-G-S-K-M-S-D-P-L-V-I-G-R-V-I-G-E-V-V-D-Y-F-T-P-S-V-K-M-S-V-T-Y-N-S-S-K-H-V-Y-N-G-H-E-L-F-P-S-S-V-T-S-K-P-R-V-E-V-H-G-G-D-L-R-S-F-F-T-M-I-M-I-D-P-D-V-P-G-P-S-D-P-Y-L-R-E-H-L-H-W-I-V-T-D-I-P-G-T-T-D-C-S-F-G-K-E-I-V-G-Y-E-M-P-R-P-N-I-G-I-H-R-F-V-F-L-L-F-K-Q-K-K-R-Q-T-V-L-T-A-P-L-S-R-D-R-F-N-T-R-K-F-A-E-E-N-E-L-G-S-P-V-A-A-V-F-F-N-C-Q-R-E-T-A-A-R-R-R"} +{"text": "### FUNCTION May form complexes with phosphorylated ligands by interfering with kinases and their effectors ### SEQUENCE -M-A-S-R-V-V-E-P-L-V-V-A-R-V-I-G-E-V-V-D-S-F-N-P-S-V-K-L-N-V-I-Y-N-G-S-K-Q-V-F-N-G-H-E-L-M-P-A-V-I-A-A-K-P-R-V-E-I-G-G-E-D-M-R-S-A-Y-T-L-I-M-T-D-P-D-V-P-G-P-S-D-P-Y-L-R-E-H-L-H-W-I-V-T-D-I-P-G-S-T-D-S-S-F-G-R-E-I-V-S-Y-E-S-P-K-P-V-I-G-I-H-R-Y-V-L-L-L-Y-K-Q-S-G-R-Q-T-V-K-P-A-A-T-R-D-H-F-N-T-R-R-Y-T-A-E-N-G-L-G-S-P-V-A-A-V-Y-F-N-A-Q-R-E-T-A-A-R-R-R"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-V-Y-Q-D-L-L-S-G-D-E-L-P-S-D-S-F-S-Y-T-E-L-G-N-G-V-L-W-E-V-Q-G-K-W-V-V-Q-G-A-V-D-V-N-I-G-A-N-P-S-A-E-G-A-D-E-D-E-G-V-D-D-Q-A-I-K-V-V-D-I-V-D-T-F-R-L-Q-E-Q-P-S-F-D-K-K-Q-F-V-A-Y-M-K-K-Y-I-K-N-L-T-P-K-L-G-A-E-Q-E-E-V-F-K-N-N-I-Q-G-A-T-K-Y-L-L-S-K-L-S-D-L-Q-F-F-V-G-E-S-M-A-D-D-T-G-M-V-F-A-Y-Y-K-D-G-A-T-D-P-T-F-L-Y-L-A-H-G-L-K-E-V-K-C"} +{"text": "### FUNCTION Facilitates protein transport into the nucleus Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import ### SEQUENCE -M-D-A-D-A-V-A-K-A-F-V-E-H-Y-Y-R-T-F-D-T-N-R-P-A-L-V-S-L-Y-Q-D-G-S-M-L-T-F-E-G-Q-Q-F-L-G-A-A-A-I-A-G-K-L-G-S-L-P-F-A-Q-C-H-H-D-I-N-T-V-D-C-Q-P-S-G-P-Q-G-G-M-L-V-F-V-S-G-S-L-R-T-G-P-D-E-H-P-L-K-F-S-Q-M-F-Q-L-L-P-A-G-G-N-F-Y-V-Q-N-D-M-F-R-L-N-Y-G"} +{"text": "### FUNCTION This protein is essential for replication of the chromosomes and its single-stranded DNA phages It is also involved in DNA recombination and repair ### SEQUENCE -M-A-Q-R-G-V-N-K-V-I-L-I-G-T-L-G-Q-D-P-E-I-R-Y-I-P-N-G-G-A-V-G-R-L-S-I-A-T-N-E-S-W-R-D-K-Q-T-G-Q-Q-K-E-Q-T-E-W-H-K-V-V-L-F-G-K-L-A-E-I-A-S-E-Y-L-R-K-G-S-Q-V-Y-I-E-G-K-L-K-T-R-K-W-T-D-D-A-G-V-E-R-Y-T-T-E-I-I-V-S-Q-G-G-T-M-Q-M-I-G-A-R-R-D-D-S-Q-S-S-N-G-W-G-Q-S-N-Q-P-Q-N-H-Q-Q-Y-S-G-G-G-K-P-Q-S-N-A-N-N-E-P-P-M-D-F-D-D-D-I-P-F"} +{"text": "### FUNCTION Component of the spanin complex that disrupts the host outer membrane and causes cell lysis during virus exit The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans ### SEQUENCE -M-R-E-L-K-M-K-L-C-V-L-M-L-P-L-V-V-S-A-C-G-S-T-P-P-A-P-V-P-C-V-K-P-P-A-P-P-A-W-I-M-Q-P-A-P-D-W-Q-T-P-L-N-G-I-I-S-S-S-E-R-G"} +{"text": "### FUNCTION Exolysin that catalyzes the cleavage of the host peptidoglycans during virus entry ### SEQUENCE -M-I-N-K-T-T-I-K-T-V-L-I-T-L-G-V-L-A-A-V-N-K-V-S-A-L-R-S-V-K-R-L-I-S"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-N-L-I-D-L-I-L-I-A-I-Y-V-I-G-I-S-G-L-I-F-N-K-N-N-I-I-N-I-L-I-I-S-E-L-N-L-G-T-L-G-M-L-F-V-L-A-S-V-E-L-N-D-I-L-G-E-L-S-G-L-Y-I-L-T-F-T-A-A-E-S-A-I-G-L-A-I-V-V-I-L-Y-S-K-T-G-I-I-N-I-R-H-L-N-K-L-K-G"} +{"text": "### FUNCTION One of the components of the core complex of photosystem II and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-V-P-T-S-F-L-L-I-I-Y-V-K-T-V-S-Q-N-N"} +{"text": "### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-T-Q-L-N-S-F-F-Y-V-S-D-N-T-G-V-K-K-I-F-S-I-Q-N-I-T-R-N-S-F-L-V-N-T-T-D-I-I-L-G-I-I-K-E-I-S-F-K-S-S-F-K-Y-S-E-I-V-Y-G-F-V-V-R-L-K-K-T-Q-N-I-Q-N-R-Y-N-Y-I-F-N-E-N-A-V-I-L-I-D-K-N-F-N-P-L-G-T-R-I-F-G-L-F-P-E-N-L-K-N-N-N-Y-L-K-L-N-S-L-V-L-N-I-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-K-K-K-F-R-T-K-L-K-K-L-Q-Y-F-K-L-T-F-L-P-G-F-C-T-K-L-L-K-K-E-L-V-P-I-K-K-G-K-T-S-S-F-R-I-Q-L-L-E-K-Q-K-L-K-Y-N-Y-R-L-K-E-N-Q-I-K-K-Y-F-K-Y-I-K-L-L-K-I-F-N-L-I-Q-I-I-E-L-R-L-D-A-T-I-F-R-L-G-F-A-K-S-I-N-Q-A-R-Q-L-I-T-H-G-F-I-F-I-N-S-I-L-V-K-K-P-S-F-I-L-T-E-K-D-L-I-Y-I-N-P-K-K-F-T-I-I-L-I-C-R-I-N-L-F-F-R-Y-Y-N-K-Y-N-L-Y-I-Y-T-L-C-V-E-Y-L-K-F-K-L-Q-K-E-F-Y-F-K-L-Y-L-F-I-P-F-D-E-N-L-I-K-Y-Y-Y-K-F"} +{"text": "### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-I-A-I-S-I-S-G-L-I-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D"} +{"text": "### FUNCTION Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5 This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells ### SEQUENCE -M-Y-R-M-Q-L-L-S-C-I-A-L-S-L-A-L-I-T-N-S-A-P-T-S-S-S-T-K-K-T-Q-L-Q-L-E-H-L-L-L-D-L-Q-M-L-L-N-G-I-N-N-Y-K-N-P-K-L-T-R-M-L-T-F-K-F-Y-M-P-K-K-A-T-E-L-K-H-L-Q-C-L-E-E-E-L-K-P-L-E-E-V-L-N-L-A-Q-S-K-N-F-H-L-R-D-T-R-D-I-I-S-N-I-N-V-L-V-L-E-L-K-G-S-E-T-T-F-T-C-E-Y-D-D-D-T-A-T-I-I-E-F-L-N-G-W-I-T-F-C-Q-S-I-I-S-T-L-T"} +{"text": "### FUNCTION Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle ### SEQUENCE -M-V-S-R-K-A-V-A-V-L-L-M-V-H-V-A-V-M-L-A-S-Q-T-E-A-F-V-P-I-F-T-H-S-E-L-Q-R-I-R-E-K-E-R-N-K-G-Q-K-K-S-L-I-V-Q-Q-R-S-E-E-V-G-P-L-D-P-V-E-P-P-E-E-E-E-N-E-V-I-K-L-T-A-P-V-A-I-G-T-R-M-N-S-R-Q-L-E-K-Y-R-A-A-L-E-G-L-L-S-E-V-L-L-P-A-R-N-D-K"} +{"text": "### FUNCTION Inhibitor of lipoprotein binding to the low density lipoprotein Binds free fatty acids and reduces their intracellular esterification Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein ### SEQUENCE -M-R-L-L-L-S-L-P-V-L-L-V-A-L-S-V-V-L-E-R-P-A-P-A-Q-A-A-P-D-F-S-S-T-L-E-G-L-P-D-K-L-K-E-F-G-N-T-L-E-D-K-A-K-K-A-I-E-R-I-K-Q-S-D-L-P-A-K-T-R-N-W-F-T-E-T-F-G-K-V-R-D-T-F-K-A-T-F-S"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-S-K-R-G-R-G-G-S-S-G-A-K-F-R-I-S-L-G-L-P-V-G-A-V-I-N-C-A-D-N-T-G-A-K-N-L-Y-I-I-S-V-K-G-I-K-G-R-L-N-R-L-P-A-A-G-V-G-D-M-V-M-A-T-V-K-K-G-K-P-X-L-R-K-K-V-H-P-A-V-V-I-R-Q-R-K-S-Y-R-R-K-D-G-V-F-L-Y-F-E-D-N-A-G-V-I-V-N-N-K-G-E-M-K-G-S-A-I-T-G-P-V-X-K-E-C-A-D-L-W-P-X-I-A-S-N-A-G-S-I-A"} +{"text": "### FUNCTION Binds and deliver cytosolic copper to the copper ATPase proteins May be important in cellular antioxidant defense ### SEQUENCE -M-P-K-H-E-F-S-V-D-M-T-C-E-G-C-S-N-A-V-T-R-V-L-N-K-L-G-G-V-Q-F-D-I-D-L-P-N-K-K-V-C-I-N-S-E-H-S-V-D-T-L-L-E-T-L-G-K-T-G-K-A-V-S-Y-L-G-P-K"} +{"text": "### FUNCTION Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5 This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells ### SEQUENCE -M-Y-K-M-Q-L-L-S-C-I-A-L-T-L-V-L-V-A-N-S-A-P-T-T-S-S-S-T-K-E-T-Q-Q-Q-L-E-Q-L-L-L-D-L-R-L-L-L-N-G-V-N-N-Y-E-N-P-Q-L-S-R-M-L-T-F-K-F-Y-T-P-K-K-A-T-E-L-T-H-L-Q-C-L-P-E-E-L-K-L-L-E-E-V-L-Y-L-A-P-N-K-N-F-H-L-T-D-I-K-E-L-M-S-N-I-N-V-T-L-L-K-L-K-G-S-E-T-R-F-K-C-E-Y-D-D-E-T-A-T-I-T-E-F-L-N-K-W-I-T-F-C-Q-S-I-F-S-T-L-T"} +{"text": "### FUNCTION Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5 This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells ### SEQUENCE -M-Y-K-M-Q-L-L-S-C-I-A-L-T-L-A-L-V-A-N-G-A-P-T-S-S-S-T-E-N-T-K-K-Q-V-Q-S-L-L-Q-D-L-H-L-L-L-K-E-I-N-N-H-E-N-L-K-L-F-R-M-L-A-F-K-F-Y-M-P-K-K-A-T-E-L-K-H-L-Q-C-L-A-E-E-L-K-P-L-E-D-V-L-N-V-A-Q-S-K-T-Q-N-S-I-D-I-K-D-L-M-D-N-I-N-R-I-V-L-T-L-K-G-S-E-T-R-F-T-C-E-Y-D-D-E-T-V-T-A-V-E-F-L-N-K-W-I-T-F-C-Q-S-I-Y-S-T-M-T"} +{"text": "### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs Pol II is the central component of the basal RNA polymerase II transcription machinery It is composed of mobile elements that move relative to each other RPB11 is part of the core element with the central large cleft ### SEQUENCE -M-N-A-P-A-A-F-E-S-F-L-L-L-D-D-K-K-F-Y-I-E-K-D-T-K-V-P-N-A-A-I-F-T-I-M-K-E-D-H-T-L-G-N-M-L-K-I-Q-L-L-K-D-P-E-V-L-F-A-G-Y-K-N-P-H-P-L-E-H-K-I-L-L-R-I-Q-T-T-N-N-T-T-P-A-D-A-L-T-T-A-I-T-D-L-V-G-E-L-S-L-L-E-H-R-I-D-A-A-I-K-K-C-T-Q-S-G-D-Q-E-R-G-Y-N"} +{"text": "### FUNCTION Required for ribosome biogenesis Part of a complex which catalyzes pseudouridylation of rRNA This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 Pseudouridine ### SEQUENCE -M-F-L-R-Y-F-L-D-E-N-Q-Q-R-V-Y-T-L-K-R-T-A-P-S-G-E-Q-T-L-T-A-H-P-A-R-F-S-P-E-D-K-N-S-K-Y-R-I-I-I-K-K-R-F-G-L-L-P-T-Q-K-A-K-T-V-C"} +{"text": "### FUNCTION Stabilizer subunit of the dolichol-phosphate-mannose synthase complex ### SEQUENCE -M-V-S-Q-L-V-T-Y-S-A-H-V-I-L-F-V-L-V-W-L-L-A-Y-T-D-V-V-P-V-L-S-Y-L-P-E-C-L-H-C-L-V-N-Y-A-P-F-F-A-V-L-F-L-G-I-Y-A-V-F-N-V-V-Y-G-V-A-T-F-N-D-C-A-E-A-K-V-E-L-L-G-E-I-K-E-A-R-E-E-L-K-R-K-R-I-I-D"} +{"text": "### FUNCTION Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions ### SEQUENCE -M-G-K-R-K-S-K-R-K-A-P-T-K-A-K-A-V-M-P-L-D-T-Q-F-N-C-P-F-C-N-H-E-R-V-C-E-V-K-M-D-R-E-K-N-V-G-Y-I-S-C-R-V-C-S-E-D-F-Q-T-N-I-N-Y-L-S-E-P-I-D-V-Y-S-D-W-V-D-A-C-E-Q-A-N-N-A"} +{"text": "### FUNCTION Ribosomal protein required for normal mitochondrial function and normal larval development Thought to have a role in insulin/IGF signaling ### SEQUENCE -M-L-K-L-A-S-S-L-R-T-G-L-I-S-R-S-I-R-T-L-A-P-T-V-N-P-A-E-Q-Q-Q-V-Q-A-V-L-P-D-K-L-Y-S-S-V-E-I-E-Y-R-G-H-D-K-A-V-L-K-S-Y-T-S-F-L-Q-Q-V-C-Q-H-L-E-I-P-Q-G-R-L-E-V-L-P-Y-I-R-W-V-Q-P-A-L-R-S-K-F-V-H-K-K-Y-K-L-H-Y-E-T-R-T-H-I-S-K-L-E-I-L-N-V-T-G-S-T-A-S-T-F-L-E-Y-I-Q-R-N-I-P-E-G-V-G-M-R-V-G-F-T-E-L-Q-P-L-P-L-T-I-Q-K-N"} +{"text": "### FUNCTION Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm May also be involved in ribosome biogenesis ### SEQUENCE -G-T-T-F-R-T-S-I-A-E-N-A-L-V-G-S-Y-A-V-V-N-N-K-G-C-M-V-H-P-K-T-P-A-Q-D-M-D-E-I-A-S-L-L-Q-V-P-V-V-A-G-T-I-N-R-G-N-A-A-I-G-S-G-L-V-V-N-D-W-A-A-F-C-G-L-N-T-T-A-T-E-I-T-V-V-E-R-I-F-Q-L-R-R-D-L-G-G-G-R-A-N-L-L-Q-Q-L-R-D-T-L-V-D-E-L-A"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-K-V-Y-K-D-I-F-T-N-D-E-V-C-S-D-S-Y-I-Q-E-D-P-F-G-N-P-E-F-R-E-I-A-F-E-V-K-S-N-K-R-I-K-G-N-D-D-Y-G-I-A-D-N-S-E-D-A-V-D-G-M-G-A-D-V-E-H-V-I-D-I-V-D-S-F-Q-L-T-S-T-S-L-S-K-K-E-Y-S-A-Y-V-K-N-F-M-Q-R-I-L-K-H-L-E-E-K-K-P-D-R-V-D-I-F-K-T-K-A-Q-P-L-I-K-H-I-L-T-N-F-D-D-F-E-F-Y-M-G-E-S-L-D-M-E-A-G-L-I-Y-S-Y-Y-K-G-E-E-I-T-P-R-F-V-Y-I-S-D-G-L-F-E-E-K-Y"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-V-M-I-V-A-V-L-F-L-T-A-W-T-F-V-T-A-D-S-I-R-A-L-E-D-L-F-A-K-A-P-D-E-M-E-N-S-G-A-S-P-L-N-E-R-D-C-R-P-V-G-Q-Y-C-G-I-P-Y-E-H-N-W-R-C-C-S-Q-L-C-A-I-I-C-V-S"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-V-V-I-V-A-V-L-F-L-T-A-C-Q-L-I-T-A-E-T-Y-S-R-G-E-Q-K-H-R-A-L-S-S-T-D-K-N-S-K-L-T-R-T-C-N-T-P-T-Q-Y-C-T-L-H-R-H-C-C-S-L-Y-C-H-K-T-I-H-A-C-A"} +{"text": "### FUNCTION Neuropeptide that triggers the performance of ecdysis behaviors at the end of a molt It triggers adult behavior patterns larval, pupal and adult ecdysis, and plasticization during the molt ### SEQUENCE -C-K-K-M-V-G-A-Y-F-E-G-E-L-C-A-D-A-C-L-K-F-K-G-K-M-C-P-T-A-R-T-S-P-P-S-R-P-S-S-T-S-L-S-S-R-C-C-S-I-K-S-L-C-K-A"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-M-V-I-V-A-V-L-L-L-T-A-C-Q-L-I-T-A-D-D-S-R-G-T-Q-K-H-R-S-L-R-S-T-T-K-V-S-K-A-T-D-C-I-E-A-G-N-Y-C-G-P-T-V-M-K-I-C-C-G-F-C-S-P-Y-S-K-I-C-M-N-Y-P-K-N"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-V-M-I-V-A-V-L-L-L-T-A-C-Q-L-I-T-A-D-D-S-R-G-T-Q-K-H-R-S-L-R-S-T-T-K-V-S-K-S-T-S-C-M-E-A-G-S-Y-C-G-S-T-T-R-I-C-C-G-Y-C-A-Y-F-G-K-K-C-I-D-Y-P-S-N"} +{"text": "### FUNCTION Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors and thus inhibit them ### SEQUENCE -M-G-M-R-M-M-F-T-V-F-L-L-V-V-L-A-T-T-V-V-S-F-T-S-G-R-R-T-F-H-G-R-N-A-A-A-K-A-S-G-L-V-S-L-T-D-R-R-P-E-C-C-S-H-P-A-C-N-V-D-H-P-E-I-C-R"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-V-V-I-V-A-V-L-F-L-T-A-W-T-F-V-T-A-V-P-H-S-S-N-A-L-E-N-L-Y-L-K-A-H-H-E-M-N-N-P-E-A-S-E-L-N-K-R-C-Y-D-G-G-T-S-C-D-S-G-I-Q-C-C-S-G-W-C-I-F-V-C-F"} +{"text": "### FUNCTION Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels ### SEQUENCE -M-K-L-T-C-M-V-I-V-A-V-L-F-L-T-A-W-T-F-V-T-A-I-T-S-N-G-L-E-N-L-F-P-N-A-H-H-E-M-K-N-P-E-A-S-K-L-N-K-R-C-V-P-Y-E-G-P-C-N-W-L-T-Q-N-C-C-D-A-T-C-V-V-F-W-C-L"} +{"text": "### FUNCTION Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca complex are a number of protein kinases and phosphatases ### SEQUENCE -M-A-D-Q-L-T-E-E-Q-I-A-E-F-K-E-A-F-S-L-F-D-K-D-G-N-G-N-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-G-E-L-Q-D-M-I-N-E-V-D-A-D-G-N-G-T-I-D-F-P-E-F-L-T-M-M-A-R-K-M-K-D-T-D-S-E-E-E-I-R-E-A-F-K-V-F-D-K-D-G-N-G-F-I-S-A-A-E-L-R-H-V-M-T-N-P-G-E-K-L-T-D-E-E-V-D-E-M-I-R-E-A-D-I-D-G-D-G-Q-V-N-Y-E-E-F-V-K-M-M-T-S-K"} +{"text": "### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell Required for pre-rRNA processing and maturation of 40S ribosomal subunits ### SEQUENCE -M-P-G-Y-T-V-K-D-V-N-Q-Q-E-F-V-K-A-L-A-A-F-F-K-K-S-G-K-L-K-K-P-D-W-V-D-T-V-K-L-G-K-H-K-E-L-A-P-F-D-I-D-W-Y-Y-I-R-T-A-S-V-A-R-H-L-Y-M-R-G-G-V-G-V-G-A-M-T-K-I-Y-G-G-R-Q-R-N-G-T-R-P-S-H-Y-S-R-G-S-R-N-V-A-R-K-V-L-Q-S-L-E-M-L-K-M-V-E-K-D-P-N-G-G-R-R-L-T-S-I-G-Q-R-D-M-D-R-I-A-G-Q-V-V-V-L-S-K-K-H"} +{"text": "### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -V-G-I-V-G-K-Y-G-T-R-Y-G-A-S-L-R-K-M-V-K-K-I-E-I-T-Q-H-S-K-Y-T-C-T-F-C-G-K-T-K-M-K-R-R-A-V-G-I-W-H-C-G-S-C-M-K-T-V-A-G-G-A-W-T-Y-N-T-S-S-A-V-T-V-K-S-A-I-R-R-L-R-E-M-K-D-Q"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-E-Q-I-L-D-V-E-S-L-K-K-L-T-P-E-Q-Q-K-T-L-I-S-G-V-K-Q-Q-A-A-I-L-T-A-Q-N-M-I-T-D-X-S-E-R-C-L-T-K-C-I-T-X-P-G-S-A-L-S-X-T-E-R-Q-C-L-Q-R-C-M-D-R-F-M-E-T-Y-X-L-A-S-Q-X-L-Q-N-R-V-X-E-E-I-A-A-X-T-R-M-T"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-S-D-F-E-N-L-S-G-N-D-K-E-L-Q-E-F-L-L-I-E-K-Q-K-A-Q-V-N-A-Q-I-H-E-F-N-E-I-C-W-E-K-C-I-G-K-P-S-T-K-L-D-H-A-T-E-T-C-L-S-N-C-V-D-R-F-I-D-T-S-L-L-I-T-Q-R-F-A-Q-M-L-Q-K-R-G-G-G-D-L"} +{"text": "### FUNCTION Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems ### SEQUENCE -M-V-I-T-L-P-K-L-K-Y-A-L-N-A-L-S-P-H-I-S-E-E-T-L-N-F-H-Y-N-K-H-H-A-G-Y-V-N-K-L-N-T-L-I-K-D-T-P-F-A-E-K-S-L-L-D-I-V-K-E-S-S-G-A-I-F-N-N-A-A-Q-I-W-N-H-T-F-Y-W-D-S-M-G-P-D-C-G-G-E-P-H-G-E-I-K-E-K-I-Q-E-D-F-G-S-F-N-N-F-K-E-Q-F-S-N-I-L-C-G-H-F-G-S-G-W-G-W-L-A-L-N-N-N-N-K-L-V-I-L-Q-T-H-D-A-G-N-P-I-K-D-N-T-G-I-P-I-L-T-C-D-I-W-E-H-A-Y-Y-I-D-Y-R-N-D-R-A-S-Y-V-K-A-W-W-N-L-V-N-W-N-F-A-N-E-N-L-K-K-A-M-Q-K"} +{"text": "### FUNCTION Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems ### SEQUENCE -M-V-I-T-L-P-K-L-K-Y-A-L-N-A-L-S-P-H-I-S-E-E-T-L-N-F-H-Y-N-K-H-H-A-G-Y-V-N-K-L-N-T-L-I-K-D-T-P-F-A-E-K-S-L-L-D-I-V-K-E-S-S-G-A-I-F-N-N-A-A-Q-I-W-N-H-T-F-Y-W-D-S-M-G-P-D-C-G-G-E-P-H-G-G-I-K-E-K-I-Q-E-D-F-G-S-F-N-N-F-K-E-Q-F-S-N-I-L-C-G-H-F-G-S-G-W-G-W-L-A-L-N-N-N-N-K-L-V-I-L-Q-T-H-D-A-G-N-P-I-K-D-N-T-G-I-P-I-L-T-C-D-I-W-E-H-A-Y-C-I-D-Y-R-N-D-R-A-S-Y-V-K-A-W-W-N-L-V-N-W-N-F-A-N-E-N-L-K-K-A-M-Q-K"} +{"text": "### FUNCTION Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis They bind voltage-independently at site-4 of sodium channels ### SEQUENCE -M-K-L-F-L-L-L-V-I-F-A-S-M-L-N-D-G-L-V-N-A-D-G-Y-I-R-G-S-D-G-C-K-V-S-C-L-W-G-N-D-F-C-D-K-V-C-K-K-S-G-G-S-Y-G-Y-C-W-T-W-G-L-A-C-W-C-E-G-L-P-D-N-E-K-W-K-Y-E-S-N-T-C-G-S-K-K"} +{"text": "### FUNCTION May play a role in lens epithelial cell differentiation ### SEQUENCE -M-Q-P-R-T-Q-P-L-A-Q-T-L-P-F-F-L-G-G-A-P-R-D-T-G-L-R-V-P-V-I-K-M-G-T-G-W-E-G-F-Q-R-T-L-K-E-V-A-Y-I-L-L-C-C-W-C-I-K-E-L-L-D"} +{"text": "### FUNCTION Transcription repressor involved in the exit of embryonic stem cells from self-renewal Acts by repressing expression of KLF4 ### SEQUENCE -M-A-R-G-Q-Q-K-I-Q-S-Q-Q-K-N-A-K-K-Q-A-G-Q-K-K-K-Q-G-H-D-Q-K-A-A-A-K-A-A-L-I-Y-T-C-T-V-C-R-T-Q-M-P-D-P-K-T-F-K-Q-H-F-E-S-K-H-P-K-T-P-L-P-P-E-L-A-D-V-Q-A"} +{"text": "### FUNCTION Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases ### SEQUENCE -M-A-E-L-K-S-F-T-L-A-D-L-S-Q-H-T-T-K-D-S-L-Y-L-A-I-H-G-K-V-Y-D-C-T-G-F-I-D-E-H-P-G-G-E-E-V-L-I-D-E-A-G-R-D-A-T-E-S-F-E-D-V-G-H-S-D-E-A-R-D-I-M-S-K-L-L-V-G-E-F-K-T-D-S-S-E-K-P-K-A-K-S-P-S-S-S-T-P-R-P-I-P-A-A-E-P-S-D-S-G-S-L-Q-Y-V-L-A-L-A-V-V-A-G-C-V-I-W-K-V-L-L"} +{"text": "### FUNCTION Subunit of the V1 complex of vacuolar ### SEQUENCE -M-A-T-S-Q-A-D-A-R-D-R-Q-F-L-A-V-I-G-D-E-D-S-V-T-G-L-L-L-A-G-I-G-H-V-T-A-P-P-D-S-Q-K-N-F-L-V-V-D-N-K-T-D-N-A-A-I-E-A-A-F-D-R-F-T-T-E-R-K-D-I-G-I-V-L-I-N-Q-H-I-A-D-R-I-R-H-R-V-D-T-H-T-A-A-F-P-T-V-L-E-I-P-S-K-D-H-P-Y-D-P-E-K-D-S-V-L-R-R-V-R-R-L-F-G-E"} +{"text": "### FUNCTION The complex LTO1YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly complex machinery May be required for biogenesis of the large ribosomal subunit and initiation of translation ### SEQUENCE -M-D-W-E-E-V-T-K-L-E-E-N-E-Y-K-R-G-Y-D-E-G-I-L-K-G-I-E-Q-G-Y-E-E-A-F-L-F-G-L-E-H-A-Y-N-K-Y-L-L-A-G-E-I-Y-G-R-V-C-F-W-L-K-E-E-N-S-Q-H-P-K-I-K-K-A-H-R-H-L-E-Q-L-K-S-L-L-E-S-L-P-T-N-N-E-L-E-E-T-D-A-G-F-D-S-Y-W-N-K-I-T-A-K-A-K-V-V-S-S-L-L-G-T-K-I-L-P-A-E-K-I-D-A-N-D-G-F-E"} +{"text": "### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane mL54 may have a meiosis-specific role as it accumulates during the middle stage of sporulation ### SEQUENCE -M-P-F-I-E-S-M-A-P-L-S-R-A-I-T-R-G-I-S-Q-F-S-C-Y-S-N-T-L-V-L-R-S-S-R-N-S-S-S-S-L-V-K-R-S-Y-V-S-S-R-V-S-P-K-K-P-Q-H-N-S-D-A-T-S-S-A-Q-K-V-A-N-K-T-H-T-S-S-V-L-P-G-T-I-L-K-G-L-C-I-K-A-G-G-V-D-P-V-A-R-E-D-H-E-Y-P-E-W-L-W-S-L-L-D-E-P-A-P-N-S-K-T-A-R-S-H-A-R-K-S-A-I-R-A-A-N-F-L-T-K-K"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-D-G-L-N-A-A-E-Q-R-E-L-A-N-R-M-E-R-K-Q-M-K-E-F-M-T-M-Y-S-K-L-V-Q-R-C-F-D-D-C-V-N-D-F-T-T-K-S-L-I-S-R-E-E-G-C-V-M-R-C-V-D-K-F-M-K-G-S-Q-R-L-N-E-R-F-Q-E-Q-N-A-A-M-M-Q-S-G-Q-L-P-G-R"} +{"text": "### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-S-F-L-F-G-G-A-P-K-M-S-S-E-Q-K-I-A-A-A-E-T-E-V-E-M-I-T-D-M-F-N-R-L-S-E-S-C-S-K-K-C-I-P-N-D-Y-R-E-G-D-L-N-K-G-E-S-V-C-L-D-R-C-V-G-K-F-F-E-V-N-I-K-V-S-E-K-M-Q-G-V-A-G-Q-Q-Q-G-G-A-G-L-S-L"} +{"text": "### FUNCTION Binds and compacts DNA to form nucleosome-like structures ### SEQUENCE -M-A-E-L-P-I-A-P-V-D-R-L-I-R-K-A-G-A-A-R-V-S-E-E-A-A-K-V-L-A-E-H-L-E-E-K-A-L-E-I-A-K-K-A-V-A-L-A-Q-H-A-G-R-K-T-V-K-A-E-D-I-K-L-A-I-K-S"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-A-R-V-A-V-V-V-K-V-Y-P-D-D-V-S-I-D-P-K-T-L-A-E-R-I-K-S-K-L-P-S-G-Y-E-V-L-A-E-G-E-E-P-I-A-F-G-L-K-A-L-K-L-V-I-A-M-N-E-D-T-E-G-G-T-E-E-V-E-Q-L-L-K-N-I-E-G-V-Q-E-V-E-V-E-N-V-S-R-M-Q"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-P-K-S-R-T-C-S-F-C-G-G-S-I-E-P-G-T-G-L-M-Y-V-L-R-N-G-Q-I-L-W-F-C-S-S-K-C-Y-K-N-F-V-K-L-R-R-K-P-D-K-L-E-W-V-R-K-V-K-K-S-L-L-D"} +{"text": "### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-S-H-E-E-L-A-E-V-L-A-K-V-L-K-K-R-G-A-V-L-R-G-D-F-V-L-S-S-G-R-R-S-S-V-Y-I-D-M-R-R-L-L-G-D-E-S-S-Y-S-V-A-L-D-L-L-L-E-V-G-G-Q-D-L-A-R-S-S-A-V-I-G-V-A-T-G-G-L-P-W-A-A-M-L-A-L-R-L-S-K-P-L-G-Y-V-R-P-E-R-K-G-H-G-T-L-S-Q-V-E-G-D-P-P-K-G-R-V-V-V-V-D-D-V-A-T-T-G-T-S-I-A-K-S-I-E-V-L-R-S-N-G-Y-T-V-G-T-A-L-V-L-V-D-R-G-E-G-A-G-E-L-L-A-R-M-G-V-R-L-V-S-V-A-T-L-K-T-I-L-E-K-L-G-W-G-G-E"} +{"text": "### FUNCTION Stimulates transcription elongation ### SEQUENCE -M-E-G-G-V-D-A-R-F-Y-A-I-L-V-T-S-G-A-E-V-N-V-A-T-I-I-A-E-R-A-R-A-L-G-L-D-I-R-S-I-I-V-P-P-R-I-K-G-Y-V-I-L-E-A-H-D-P-G-D-V-Y-D-A-T-R-G-L-R-H-V-K-R-R-R-P-L-I-L-K-F-E-E-V-M-K-L-V-K-P-E-V-E-I-P-A-L-K-P-G-Q-V-V-E-I-V-A-G-A-F-K-G-M-K-A-R-V-I-D-V-N-Q-S-K-G-Q-V-T-V-S-L-L-E-P-L-F-R-A-T-A-T-I-P-I-D-E-V-R-P-V-E-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-V-K-G-S-Q-V-K-P-S-T-T-E-L-L-L-K-A-V-S-A-K-A-P-S-G-D-P-I-H-Q-K-I-G-D-L-P-F-E-K-I-V-E-I-A-I-E-K-K-P-D-L-L-A-K-T-L-K-A-A-V-K-T-I-L-G-S-A-R-S-I-G-V-T-V-D-G-K-D-P-K-E-V-T-R-Q-V-D-E-G-V-Y-D-A-V-L-A-K-Y-E-E-K-W-E-E-A-E-G"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-Q-E-G-K-A-Y-I-H-L-A-L-A-I-Y-Y-A-G-G-K-I-D-E-E-T-L-K-K-A-A-E-A-I-G-M-Q-V-D-E-A-K-I-K-M-L-V-A-S-L-E-E-V-N-L-E-E-V-L-K-Q-A-V-A-A-P-V-A-A-A-A-A-A-P-A-A-A-P-A-A-E-E-K-A-E-E-E-K-K-E-E-E-E-E-K-K-E-E-E-V-D-L-S-G-L-S-G-M-F-G-F"} +{"text": "### FUNCTION Functions by promoting the formation of the first peptide bond ### SEQUENCE -M-S-V-N-Y-A-T-L-G-D-L-K-K-G-S-Y-I-V-I-D-G-E-P-C-R-I-V-E-M-S-R-A-K-T-G-K-H-G-S-A-K-A-H-V-V-A-I-C-V-F-S-G-Q-K-K-S-L-V-A-P-V-D-T-R-V-Q-I-P-V-I-E-K-R-L-G-Q-V-L-A-D-M-G-D-M-V-Q-I-M-D-L-E-T-Y-D-T-F-E-V-E-K-P-G-G-N-E-E-E-E-Q-L-A-A-K-L-Q-P-G-V-T-V-E-Y-W-L-I-M-G-K-P-K-I-I-R-I-R-S-S-S-S"} +{"text": "### FUNCTION Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs ### SEQUENCE -M-K-P-G-G-P-Y-G-D-V-Y-V-L-R-L-G-H-R-P-E-R-D-K-R-V-T-T-H-V-A-L-V-A-R-A-F-G-A-N-G-F-V-L-E-G-V-C-D-E-G-V-V-E-S-V-R-R-V-V-A-R-W-G-G-P-F-T-V-E-C-G-V-S-G-R-R-Y-V-R-M-W-R-E-G-G-G-E-V-V-H-L-T-M-Y-G-V-N-V-D-D-V-A-P-V-I-A-A-S-P-R-R-K-L-V-V-V-G-A-E-K-V-E-R-F-Y-Y-E-E-A-D-W-N-V-S-V-G-T-Q-P-H-S-E-V-A-A-L-A-L-F-L-D-R-L-F-R-G-E-W-R-F-I-D-Y-S-G-G-F-L-R-V-M-E-S-Q-R-G-K-R-V-E-R-K-G"} +{"text": "### FUNCTION Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein and RNA polymerase recruitment Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes ### SEQUENCE -M-K-G-K-G-R-N-R-A-V-K-S-L-E-I-Y-V-R-K-L-A-Q-A-N-G-I-K-P-E-M-A-A-H-I-F-H-L-I-Y-E-E-T-P-N-G-G-I-S-D-D-D-L-E-S-L-T-G-Y-K-Q-S-D-I-R-R-I-L-R-L-L-G-D-K-R-I-I-V-S-R-K-G-R-H-P-R-K-E-A-T-R-Y-F-W-R-I-D-S-D-T-I-N-V-S-L-L-T-L-K-K-K-V-L-E-K-L-V-V-K-E-A-H-D-S-G-N-S-Y-Y-T-C-P-R-C-G-S-K-Y-S-F-D-E-A-F-T-L-D-F-T-C-P-R-C-G-E-V-L-E-E-A-D-S-R-E-G-L-E-R-L-R-R-T-I-D-A-L-R-E-E-I-A-R-D-E-S-R-I-Y-R-S"} +{"text": "### FUNCTION A putative type II restriction enzyme, its methylase would be APE_2002 ### SEQUENCE -M-P-V-E-V-I-P-V-L-H-N-V-S-S-V-Q-R-V-V-D-M-A-R-L-S-Y-S-L-G-L-D-T-L-V-V-T-K-A-Y-G-G-A-A-Q-S-G-V-P-E-A-M-R-L-A-L-K-L-G-K-S-L-V-V-L-P-E-L-R-D-A-V-N-L-L-S-P-T-H-V-L-A-V-T-P-S-R-A-E-R-L-V-G-P-G-G-L-E-G-L-E-G-R-V-L-V-V-F-S-G-G-E-P-E-L-D-P-S-E-A-A-G-A-I-R-V-Y-I-E-G-V-E-G-K-V-G-P-I-A-E-A-A-L-I-L-Y-F-L-L-R-G-G-G-D-G-R-G"} +{"text": "### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates ### SEQUENCE -M-S-S-K-T-R-K-S-S-R-V-I-L-E-H-E-Y-V-P-E-H-R-L-L-S-I-E-E-A-V-Q-V-L-K-M-L-G-I-K-P-W-Q-L-P-K-I-S-V-N-D-P-I-A-R-L-L-K-A-K-P-G-D-I-I-E-I-T-R-R-S-Y-T-A-G-E-A-K-Y-Y-R-F-V-V-A-Y-Q-K-G-V-K"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-T-G-K-K-A-P-A-G-L-F-A-A-R-K-L-R-R-K-R-L-K-F-R-W-S-Q-R-E-F-R-I-R-M-L-D-L-K-R-K-Y-D-P-L-E-G-A-P-M-A-R-G-I-V-L-E-K-V-G-V-E-A-R-Q-P-N-S-A-L-R-K-C-V-R-V-Q-L-V-K-N-K-K-V-V-T-A-F-V-P-R-D-G-G-I-L-Y-V-D-E-H-D-E-V-I-I-E-G-I-G-G-P-R-G-R-S-M-G-D-I-P-G-V-R-Y-R-V-V-M-V-N-G-V-S-L-K-A-L-W-E-G-K-K-Q-K-P-R-K"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-F-K-L-R-I-W-L-W-S-T-N-V-R-S-L-E-N-V-V-E-Q-I-R-N-I-A-N-K-T-G-I-R-M-R-G-P-V-P-L-P-V-K-R-L-E-V-P-V-F-R-L-P-H-G-E-G-S-K-Y-W-E-H-W-E-M-K-V-H-K-R-L-I-D-L-E-A-D-E-R-V-L-R-H-L-M-R-I-K-V-P-E-D-V-Y-I-E-I-K-Q-M-T-G"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-S-I-E-P-Q-K-P-N-T-I-L-V-G-R-K-P-T-I-N-Y-V-M-A-A-L-K-L-L-N-E-E-G-A-P-E-V-V-I-K-A-R-G-R-N-I-C-N-A-V-D-T-V-E-M-L-K-N-L-F-I-K-N-L-V-I-K-K-V-N-I-Y-S-E-S-L-D-S-E-G-K-K-K-V-S-A-I-E-I-V-V-A-K-G"} +{"text": "### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-A-C-E-G-A-P-E-V-R-I-G-R-K-P-V-M-N-Y-V-L-A-I-L-T-T-L-M-E-Q-G-T-N-Q-V-V-V-K-A-R-G-R-N-I-N-R-A-V-D-A-V-E-I-V-R-K-R-F-A-K-N-I-E-I-K-D-I-K-I-D-S-Q-E-I-E-V-Q-T-P-E-G-Q-T-R-T-R-R-V-S-S-I-E-I-C-L-E-K-A-G-E-S-A"} +{"text": "### FUNCTION Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester ### SEQUENCE -M-V-G-R-L-A-R-L-R-D-S-I-A-H-T-G-V-P-M-K-T-V-E-D-E-N-F-H-I-T-L-R-F-I-G-E-V-S-E-P-V-A-A-E-I-G-E-R-L-A-S-I-R-F-E-R-F-R-I-E-L-R-G-L-G-A-F-P-R-P-D-R-P-R-V-V-W-V-G-V-G-G-G-A-G-E-L-R-R-I-R-D-E-V-E-R-I-L-T-S-M-G-F-S-P-E-K-Q-E-F-H-P-H-V-T-L-A-R-I-K-G-A-R-N-L-P-A-L-V-K-L-L-R-E-M-G-D-V-E-V-G-S-V-E-V-S-S-I-R-L-K-Q-S-I-L-T-R-Q-G-P-I-Y-K-T-L-Y-E-V-K-A-A-S-S-G-R-V"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-L-L-A-G-G-E-A-R-E-I-V-V-D-G-S-G-M-I-M-G-R-L-A-S-V-V-A-K-L-L-L-A-G-W-R-V-N-V-V-N-A-E-K-I-V-L-S-G-D-P-R-M-V-V-E-S-Y-R-T-T-V-L-G-V-K-S-H-F-S-H-K-W-R-P-K-R-P-R-T-P-Q-R-L-F-K-H-A-V-R-G-M-L-P-K-N-K-A-R-G-R-R-A-L-A-R-L-R-V-Y-V-G-V-P-D-E-L-K-G-R-E-F-V-R-F-P-E-A-D-A-S-R-L-S-S-H-Y-I-E-L-G-A-V-A-R-Q-L-G-W-K-G-G-V-E-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit ### SEQUENCE -M-A-M-Y-P-R-E-L-K-W-G-V-A-H-I-Y-S-S-F-N-N-T-H-V-H-I-T-D-L-T-G-A-E-T-V-A-R-V-T-G-G-M-V-V-K-A-D-R-E-K-P-S-P-Y-A-A-M-I-A-A-S-R-A-A-Q-K-A-M-E-R-G-I-A-A-I-H-I-K-V-R-A-P-G-G-H-G-P-K-T-P-G-P-G-A-Q-A-A-I-R-A-L-A-R-A-G-F-I-I-G-R-I-E-D-V-T-P-I-P-H-D-T-T-R-R-P-G-G-R-R-G-R-R-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-G-D-P-R-K-P-R-K-K-W-E-G-P-K-H-P-W-I-K-E-R-L-E-R-E-R-E-L-M-G-R-Y-G-L-R-N-K-K-E-L-W-K-A-E-T-L-A-R-R-F-R-H-R-A-R-S-L-L-G-L-P-P-E-V-R-R-E-A-S-R-V-L-V-E-S-L-Y-R-M-G-L-I-D-N-P-N-V-D-I-D-E-V-L-G-I-N-A-E-K-V-L-E-R-R-L-Q-T-I-V-Y-K-K-G-L-A-K-T-I-Y-Q-A-R-Q-L-V-V-H-G-H-I-A-I-A-G-R-R-V-T-S-P-G-Y-L-V-S-R-E-E-E-K-L-I-D-Y-A-P-G-S-P-F-K-E-R-A-E-E-A-A-Q-A"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-G-E-T-S-F-K-Y-I-V-R-I-A-G-V-D-I-D-G-D-L-K-L-P-Y-G-L-A-S-I-K-G-I-G-Y-T-T-A-M-A-V-I-R-M-L-G-L-D-P-E-K-K-V-G-F-L-T-E-E-E-I-R-R-L-D-E-V-L-R-D-I-T-Q-L-G-L-P-K-W-L-Y-N-R-R-K-D-Y-E-T-G-K-D-L-H-L-I-G-S-E-L-I-F-Y-A-R-R-D-I-E-R-E-M-K-I-G-S-W-R-G-I-R-H-K-Y-G-L-K-V-R-G-Q-R-T-R-T-T-G-R-L-G-M-T-I-G-V-R-K-K-R"} +{"text": "### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate forming two phosphate ions ### SEQUENCE -M-T-G-C-L-K-I-G-P-G-D-E-A-P-D-V-V-N-V-V-I-E-I-P-M-N-S-S-V-K-Y-E-F-D-K-E-A-C-I-V-K-V-D-R-F-L-Y-T-S-M-V-Y-P-F-N-Y-G-F-I-P-G-T-L-E-E-D-G-D-P-V-D-V-L-V-I-S-R-E-P-V-A-P-G-S-L-I-E-A-V-P-V-A-V-L-D-M-E-D-E-E-G-P-D-S-K-V-V-A-V-P-K-A-K-L-D-P-L-F-A-S-Y-K-D-V-G-D-I-P-D-A-L-K-S-K-I-K-H-F-F-E-H-Y-K-E-L-E-P-G-K-W-V-R-V-T-G-W-R-P-A-A-D-A-K-E-I-I-R-R-A-I-E-R-Y-K-G-A"} +{"text": "### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-E-G-E-G-L-L-V-R-K-I-R-S-G-V-V-I-D-H-I-P-P-G-R-A-F-T-M-L-K-A-L-G-L-L-P-P-R-G-Y-R-W-R-I-A-V-V-I-N-A-E-S-S-K-L-G-R-K-D-I-L-K-I-E-G-Y-K-P-R-Q-R-D-L-E-V-L-G-I-I-A-P-G-A-T-F-N-V-I-E-D-Y-K-V-V-E-K-V-K-L-K-L-P-E-E-S-Q-G-V-L-R-C-P-N-P-T-C-I-T-R-K-E-R-E-K-A-V-S-K-M-V-L-V-S-Q-D-P-P-A-Y-R-C-V-Y-C-G-T-T-V-M-G-D-E-I-H-D-L-I-S-P"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-G-E-G-Y-K-Q-A-I-V-V-R-R-D-L-G-M-G-R-G-K-A-A-A-Q-A-A-H-A-S-C-E-A-V-F-L-I-L-E-S-G-R-P-E-W-R-R-W-L-E-M-W-R-L-Q-G-Q-A-K-V-V-L-R-V-E-S-L-A-E-L-Q-E-V-Y-S-K-A-V-E-E-G-L-P-A-S-F-V-R-D-A-G-K-T-Q-L-E-P-G-T-P-T-A-A-A-V-G-P-A-P-S-R-L-V-D-R-I-T-G-G-L-K-L-F"} +{"text": "### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-S-C-R-P-S-S-V-S-I-A-V-T-G-S-S-G-V-R-V-A-L-R-L-L-E-A-L-K-G-E-V-E-I-R-G-I-I-L-T-R-G-A-E-E-V-A-R-Y-E-E-G-I-E-P-E-D-L-R-R-L-L-R-S-Y-A-P-L-Y-M-E-N-D-M-S-S-P-L-A-S-S-S-N-Q-P-D-A-M-A-I-V-P-A-S-M-K-T-V-G-L-I-A-R-G-I-P-S-S-L-P-A-R-A-A-L-A-V-L-R-L-G-R-R-L-V-V-A-P-R-E-T-P-L-G-V-V-E-L-E-N-M-L-A-I-A-R-M-G-G-I-V-V-P-L-T-L-S-F-Y-I-K-P-S-S-V-E-D-L-V-D-F-A-A-G-K-V-L-D-A-L-G-V-K-V-D-V-Y-R-R-W-R-G-P-E-E-G-D"} +{"text": "### FUNCTION Endonuclease that removes tRNA introns Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp ### SEQUENCE -M-G-D-R-C-A-P-I-K-A-S-G-V-L-I-G-D-S-V-L-V-T-D-V-E-Q-A-R-S-L-Y-S-C-G-Y-Y-G-Q-P-L-D-V-E-K-P-R-G-A-D-F-E-G-P-L-R-L-S-L-I-E-S-L-Y-L-A-E-K-G-V-L-E-V-A-K-P-D-G-S-S-V-G-V-E-D-L-R-T-A-V-R-G-N-P-R-F-S-M-L-Y-N-I-Y-R-D-L-R-E-R-G-F-V-V-R-S-G-L-K-F-G-S-D-F-A-V-Y-R-L-G-P-G-I-D-H-A-P-F-I-V-H-A-Y-S-P-E-D-N-I-D-P-V-E-I-V-R-A-G-R-L-S-H-S-V-R-K-K-F-V-F-A-V-T-R-G-G-D-V-S-Y-L-M-I-D-W-F-R-P"} +{"text": "### FUNCTION eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA ### SEQUENCE -M-S-G-S-V-L-D-E-E-A-E-K-L-M-D-Y-D-Y-L-L-E-K-L-Y-K-K-V-P-P-K-S-G-T-S-E-Y-R-I-P-E-P-Q-I-I-R-I-G-S-Q-T-V-I-R-N-F-R-E-I-A-Q-A-L-K-R-D-P-K-L-V-A-R-Y-L-Q-K-E-L-A-T-A-A-S-Y-E-E-E-S-G-Q-L-I-L-N-V-K-V-S-R-K-V-V-N-Q-F-L-Q-L-F-M-K-T-Y-V-R-C-P-T-C-G-S-I-D-T-K-L-L-R-Q-E-R-A-Y-M-L-K-C-E-A-C-G-A-E-Q-P-V-K-P-I"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-V-E-R-L-P-P-E-V-E-A-K-Y-T-K-Y-L-K-L-R-E-T-L-S-V-V-M-R-E-K-A-T-V-E-A-G-L-A-E-V-E-S-V-L-K-E-L-E-G-L-P-E-D-A-E-L-Y-R-L-T-G-F-V-L-V-K-K-S-K-N-E-V-V-E-D-L-N-K-R-K-E-D-L-E-L-K-L-K-V-L-K-S-Q-E-E-H-L-K-K-E-L-E-R-I-E-S-E-L-R-R-L-L-Q-G-G-A-V-G-G-A-K-G-A"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-S-C-G-D-K-I-R-I-A-I-V-V-S-E-F-N-Y-D-V-T-R-V-M-E-E-K-A-I-D-H-A-R-F-L-G-A-E-V-S-L-V-A-R-S-P-G-T-F-D-T-P-F-I-V-S-R-L-L-A-T-H-S-E-V-D-A-V-A-V-L-G-A-V-I-K-G-D-T-K-H-D-E-V-V-A-H-Q-A-A-R-K-L-L-D-L-S-I-E-Y-G-K-P-V-T-L-G-I-I-G-P-G-A-S-R-L-E-A-I-E-R-A-E-E-Y-A-R-R-A-V-E-S-A-V-K-L-A-R-R-S-K-E-L-S-G-E-C"} +{"text": "### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-S-G-A-G-M-V-D-I-T-A-K-E-P-V-R-R-E-A-V-A-S-G-F-I-S-L-K-R-E-T-V-K-A-I-R-E-G-R-V-E-K-G-D-V-I-S-V-A-S-V-A-A-V-L-A-V-K-E-T-P-R-L-I-P-L-T-H-P-I-P-I-E-K-V-E-P-E-V-R-V-R-D-D-G-V-E-V-R-V-R-V-A-T-T-A-K-T-G-V-E-M-E-A-L-A-G-V-T-A-A-L-L-T-V-W-D-M-V-K-S-L-E-K-D-E-T-G-N-Y-P-D-T-V-I-T-G-V-K-V-E-V-K-R-K-G"} +{"text": "### FUNCTION CRISPR ### SEQUENCE -M-R-P-V-S-M-L-K-E-Y-A-Y-C-P-R-V-A-Y-Y-M-E-V-L-R-P-S-Y-R-P-T-E-P-M-N-L-S-R-E-I-Y-S-V-D-H-V-R-G-I-L-R-S-S-G-F-R-I-V-K-E-E-W-A-V-P-L-R-S-K-R-L-G-L-Q-G-V-A-D-G-V-V-V-E-G-S-L-G-I-I-V-V-E-A-K-L-S-V-R-S-N-R-W-L-H-T-R-G-R-H-V-I-F-Q-A-A-A-Y-A-L-A-L-E-E-T-R-G-Y-S-V-D-Y-L-A-I-V-S-L-E-D-S-K-T-Y-V-V-K-M-S-P-S-L-R-R-D-V-I-R-L-A-D-D-M-N-K-T-L-D-D-G-L-E-P-P-P-K-P-G-R-K-C-V-A-C-R-F-R-R-V-C-Q-P-W-V-A-E-R-G-S-E-R"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-R-L-R-R-L-A-G-R-R-P-R-R-R-Y-V-A-F-E-V-L-S-L-D-G-P-P-P-G-K-G-E-F-E-E-A-L-R-G-V-Y-L-K-A-F-G-A-E-S-L-A-L-A-R-P-R-I-V-Y-Y-E-E-E-S-G-R-G-V-V-A-V-V-R-D-Y-R-Y-H-I-L-A-A-L-G-L-V-R-M-A-G-G-R-R-V-L-V-V-P-L-R-T-S-G-T-V-K-G-A-L-R-A-F-R-S-P-G-A-P-G-R-G-G-V"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system An RNase ### SEQUENCE -M-R-G-S-T-Q-G-C-S-P-T-G-R-E-A-I-V-L-D-T-G-A-F-I-A-G-K-A-A-A-L-P-G-R-L-A-T-P-P-R-V-L-E-E-V-R-D-R-G-S-R-S-L-L-E-L-L-Q-S-T-G-R-L-E-V-L-A-P-S-T-R-A-L-E-R-A-R-E-E-A-R-R-A-G-V-L-G-R-L-S-G-A-D-L-E-V-L-A-L-A-L-D-L-A-W-Q-G-C-R-V-A-V-A-T-D-D-Y-T-L-Q-R-L-A-A-R-L-G-L-G-V-V-R-L-R-Y-R-G-A-V"} +{"text": "### FUNCTION May be involved in maturation of the 30S ribosomal subunit ### SEQUENCE -M-V-N-A-L-E-V-P-A-D-L-L-I-R-R-V-A-R-K-L-K-E-K-Y-P-Q-V-K-P-P-A-W-A-Y-F-A-K-T-G-P-H-K-E-R-P-P-T-D-R-D-W-W-Y-V-R-A-A-S-I-L-R-K-L-Y-K-S-P-E-P-I-G-I-E-T-F-R-T-I-Y-G-G-R-Q-N-R-G-S-A-P-E-H-F-R-K-A-G-G-S-V-P-R-K-I-L-Q-Q-L-E-E-A-G-L-V-V-K-V-P-G-R-G-R-T-I-S-P-A-G-R-S-L-L-D-T-T-A-R-E-I-M-E-E-L-V-K-T-R-P-E-L-E-R-Y-L"} +{"text": "### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-A-Q-Q-M-P-S-P-E-E-I-A-A-Q-L-Q-M-I-R-D-Q-I-A-E-L-Q-G-V-L-A-Q-L-E-L-R-L-R-S-V-Q-A-A-K-E-T-V-E-K-A-A-G-Q-D-G-E-T-L-F-P-G-D-P-E-L-N-T-I-L-K-A-R-L-L-E-P-G-K-A-I-V-H-L-G-L-N-V-Y-A-K-L-D-T-A-K-A-T-E-I-L-A-K-K-E-D-A-L-K-R-S-L-E-T-L-K-Q-E-L-D-K-L-S-R-T-H-D-Q-Y-L-Q-L-L-Q-A-L-T-A-G-Q-A-A-Q-Q-A-G-Q-Q-Q-K-Q-G-S"} +{"text": "### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-G-G-Q-V-I-E-V-E-V-A-G-V-R-F-L-L-R-K-D-L-R-Y-T-E-S-D-E-W-A-R-L-E-D-G-V-A-T-V-G-I-T-D-F-A-Q-K-E-L-K-D-I-V-G-V-E-L-P-E-K-G-R-K-V-K-K-G-E-A-V-A-T-V-E-S-I-K-A-T-A-D-I-Y-A-P-L-S-G-E-I-V-D-V-N-E-K-L-L-D-Q-P-E-L-I-N-D-D-P-Y-G-E-G-W-I-F-K-I-K-V-E-D-P-G-E-F-E-S-L-L-T-P-E-Q-Y-V-E-S-V-R-K-R-K-E"} +{"text": "### FUNCTION S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 ### SEQUENCE -M-G-S-I-E-E-V-L-L-E-E-R-L-I-G-Y-L-D-P-G-A-E-K-V-L-A-R-I-N-R-P-S-K-I-V-S-T-S-S-C-T-G-R-I-T-L-I-E-G-E-A-H-W-L-R-N-G-A-R-V-A-Y-K-T-H-H-P-I-S-R-S-E-V-E-R-V-L-R-R-G-F-T-N-L-W-L-K-V-T-G-P-I-L-H-L-R-V-E-G-W-Q-C-A-K-S-L-L-E-A-A-R-R-N-G-F-K-H-S-G-V-I-S-I-A-E-D-S-R-L-V-I-E-I-M-S-S-Q-S-M-S-V-P-L-V-M-E-G-A-R-I-V-G-D-D-A-L-D-M-L-I-E-K-A-N-T-I-L-V-E-S-R-I-G-L-D-T-F-S-R-E-V-E-E-L-V-E-C-F"} +{"text": "### FUNCTION Specifically catalyzes the N1-methylation of pseudouridine at position 54 in tRNAs ### SEQUENCE -M-S-L-Y-V-V-I-S-P-T-G-R-T-D-G-N-I-P-A-R-G-Y-A-G-P-S-G-R-L-D-V-I-A-R-A-Y-N-A-I-L-E-P-N-A-T-L-A-A-L-L-M-G-G-P-L-P-P-R-L-L-I-A-P-L-S-C-K-D-I-V-R-S-E-R-S-F-M-I-E-A-S-R-A-L-R-G-R-R-S-C-F-T-V-N-D-E-G-V-E-A-L-A-S-L-L-R-R-F-K-P-R-I-L-L-A-E-K-G-G-D-I-S-S-H-W-G-E-M-C-S-S-S-P-T-F-I-A-G-S-H-L-D-P-P-H-G-L-I-K-H-L-E-R-S-L-G-G-F-L-R-V-S-V-G-P-L-S-L-H-T-D-H-V-F-L-L-V-S-A-L-R-L-P-M-H-A-T-S-I-E-H-H"} +{"text": "### FUNCTION Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP ### SEQUENCE -M-V-F-L-R-E-K-E-G-P-S-G-G-S-G-R-R-I-I-L-W-P-A-Y-F-D-S-T-L-P-R-R-L-G-R-R-V-P-R-D-M-G-V-P-S-P-K-P-E-D-V-A-E-A-A-R-R-A-G-F-E-A-V-V-E-E-S-S-Y-P-R-L-W-W-R-V-R-R-R-I-V-V-L-A-P-E-D-V-S-K-T-D-I-I-K-A-V-A-T-E-L-R-K-I-A-A-A-R-R-K-R-S"} +{"text": "### FUNCTION Involved in protein export The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex ### SEQUENCE -M-S-V-R-R-R-R-E-R-R-A-T-P-V-T-A-A-G-L-L-S-F-Y-E-E-Y-E-G-K-I-K-I-S-P-T-I-V-V-G-A-A-I-L-V-S-A-V-V-A-A-A-H-I-F-L-P-A-V-P"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-G-K-G-T-P-S-M-G-K-H-G-R-S-K-T-H-I-V-C-R-R-C-G-R-R-S-Y-N-V-A-K-G-Y-C-A-A-C-G-F-G-R-S-R-R-M-R-R-Y-S-W-Q-N-K-K-W-N-R-V-R-V-V"} +{"text": "### FUNCTION A probable chromatin protein, binds double-strand DNA without sequence specificity Constrains negative DNA supercoils ### SEQUENCE -M-S-Q-K-Q-L-P-P-V-K-V-R-D-P-T-T-G-K-E-V-E-L-T-P-I-K-V-W-K-L-S-P-R-G-R-R-G-V-K-I-G-L-F-K-S-P-E-T-G-K-Y-F-R-A-K-V-P-D-D-Y-P-E-T-G"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-F-P-K-R-I-R-T-Y-C-P-R-C-N-T-H-T-E-H-R-V-A-Q-Y-R-A-G-K-R-R-A-M-A-L-G-E-R-R-Y-R-R-K-Q-E-G-Y-G-S-Q-R-R-P-E-Q-K-R-F-A-K-V-T-K-K-Q-V-L-V-I-T-C-T-V-C-G-R-K-R-P-F-L-G-I-R-L-K-R-L-E-L-V-D-V-V-R"} +{"text": "### FUNCTION Catalyzes the formation of CDP-2,3-bis- and CTP This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-A-L-E-L-A-V-D-W-R-I-D-N-I-L-E-A-I-I-L-M-L-P-A-M-I-A-N-A-T-P-V-V-A-G-G-R-R-P-V-D-M-G-V-V-L-P-D-G-R-R-L-L-G-D-G-K-T-I-E-G-L-L-A-G-F-A-A-G-S-A-A-G-V-L-A-A-L-A-S-G-N-M-L-L-A-V-H-S-P-A-I-A-L-G-A-L-A-G-D-M-A-G-S-F-V-K-R-R-L-G-I-E-R-G-R-P-A-P-L-L-D-Q-L-D-F-Y-L-G-A-L-A-V-S-I-A-L-G-Y-T-W-T-P-R-V-A-V-E-A-A-A-A-V-L-L-L-H-L-A-A-N-I-T-A-Y-L-L-G-L-K-K-V-P-W"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-K-V-Q-G-D-P-R-R-F-A-D-T-V-L-E-K-P-F-K-E-A-L-A-R-V-E-E-A-R-E-A-G-L-K-L-V-E-E-A-Y-K-S-A-L-S-A-A-R-K-R-L-E-S-R-V-E-E-A-R-E-R-L-Q-G-L-K-S-K-A-D-L-E-V-R-T-E-A-E-R-V-K-D-E-L-V-S-R-L-I-E-E-A-L-A-E-F-R-R-R-K-A-G-M-E-S-Y-R-Q-Y-L-E-R-V-L-G-S-A-A-G-E-S-G-G-S-V-A-K-V-L-C-A-P-E-D-E-E-I-V-R-E-V-L-G-K-L-G-L-D-G-V-S-V-E-A-V-E-G-I-Y-G-G-V-V-V-E-L-A-E-G-A-R-L-D-Y-T-V-N-N-I-I-A-A-E-E-P-R-L-R-R-A-V-K-R-A-L-F-E-A"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-F-E-M-R-P-E-W-K-K-F-R-Y-R-G-R-T-L-E-E-L-L-K-M-D-I-E-E-L-A-R-L-F-P-A-R-Q-R-R-S-L-L-R-G-L-T-P-A-Q-Q-K-L-L-L-K-V-R-K-I-R-R-R-L-E-E-G-R-L-K-R-P-P-V-I-R-T-H-V-R-D-M-V-I-L-P-E-M-V-G-L-T-I-A-V-Y-N-G-K-E-F-I-P-V-K-I-V-P-E-M-I-G-H-Y-L-G-E-F-S-P-T-T-R-I-V-Q-H-G-E-P-G-L-K-A-T-R-S-S-L-H-V-A-S-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-P-R-W-G-Y-S-V-K-L-R-D-E-S-E-V-A-K-A-V-L-R-N-V-P-V-H-P-K-I-M-A-E-V-A-R-A-I-S-G-M-R-V-D-E-A-R-R-Y-L-R-A-V-I-E-K-R-E-A-V-P-F-R-R-A-H-G-K-Q-A-H-R-R-G-L-A-D-K-W-G-W-P-V-G-R-Y-P-V-K-A-A-R-Y-M-L-K-L-L-D-N-V-E-A-N-A-A-N-K-N-L-D-V-E-R-L-K-I-I-H-V-A-A-H-K-G-I-T-L-K-R-W-M-P-R-A-W-G-R-A-T-P-R-N-R-V-H-S-H-I-E-I-M-V-R-E-V"} +{"text": "### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-K-G-R-R-P-S-H-R-R-Q-L-I-P-P-L-L-T-G-L-R-V-K-V-L-A-H-S-D-P-S-L-E-G-L-E-G-W-V-V-V-E-E-A-R-S-L-R-I-L-T-L-E-G-R-V-S-T-V-L-K-D-L-A-V-I-E-V-E-A-P-G-G-E-Y-I-R-I-S-G-R-V-L-I-G-N-P-L-D-R-V-K-E-Y-R-W-R-V-S-R-R-C-R-S-S-S-R-L-K-T"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-F-K-Q-V-K-N-L-K-I-P-G-V-E-P-P-E-K-V-C-S-D-P-N-C-P-W-H-G-T-L-R-V-R-G-V-L-L-E-G-V-V-A-K-A-R-A-R-R-M-V-V-V-Q-H-V-Y-L-Y-Y-D-K-K-Y-N-R-Y-E-R-R-S-K-K-I-H-A-H-L-P-D-C-I-S-V-K-E-G-D-V-V-V-I-G-E-T-M-P-I-S-K-T-V-K-F-T-V-L-G-V-K-R-R"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-A-K-K-K-K-Y-G-V-V-V-S-R-Y-G-V-N-T-G-L-Q-V-G-S-Y-V-P-V-A-D-N-S-G-A-K-E-V-M-I-I-S-V-P-Q-V-K-T-R-L-R-R-L-P-S-A-G-V-G-D-L-V-V-V-S-V-K-K-G-T-P-Q-M-R-R-Q-V-V-Y-A-V-V-V-R-Q-R-R-P-F-R-R-P-D-G-T-W-V-S-F-E-D-N-A-V-V-I-V-N-P-D-G-T-P-R-G-S-E-V-R-G-P-I-A-R-E-A-A-E-R-W-P-R-V-A-K-I-A-T-M-I-V"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-P-V-L-T-R-S-R-Q-P-R-K-Q-R-R-A-L-Y-R-A-P-L-H-A-R-Q-K-L-V-S-A-T-L-S-P-E-L-R-E-K-Y-G-V-R-S-L-P-V-R-K-G-D-K-V-R-V-M-R-G-D-F-K-G-H-E-G-K-V-V-K-V-D-L-R-R-L-R-I-Y-I-D-G-V-T-V-T-K-A-D-G-T-P-V-F-R-P-I-H-P-S-N-V-M-I-V-E-L-D-L-S-D-E-Y-R-K-K-M-I-E-R-R-A-A-G-R-R-G-G-G-N-S-E"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-A-K-A-Q-S-L-P-I-P-P-E-R-V-S-E-I-L-D-E-W-K-R-S-P-M-R-R-P-R-I-V-K-V-T-V-N-I-S-I-G-Q-S-G-E-R-L-Q-R-A-A-E-V-L-E-E-L-T-G-Q-K-P-V-F-R-K-A-K-R-T-I-R-A-F-G-V-R-K-G-E-N-I-A-V-M-V-T-L-R-G-E-K-A-L-N-F-L-K-R-A-L-D-A-V-G-H-R-I-K-T-S-S-I-D-E-H-G-N-V-S-F-G-I-E-E-H-I-L-I-P-G-V-K-Y-D-P-R-V-G-I-L-G-M-D-V-A-I-T-I-Q-R-P-G-H-R-I-V-E-R-R-R-Q-R-R-G-H-I-P-R-R-H-R-V-T-R-E-E-T-M-V-L-L-N-Q-L-F-G-V-T-F-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-L-D-T-L-A-N-A-M-A-A-I-K-N-A-E-M-R-G-K-G-E-A-I-I-M-P-S-S-K-L-I-A-N-V-L-R-I-L-E-K-E-G-Y-I-G-G-F-E-Y-I-D-D-G-R-W-G-K-F-R-V-K-L-L-G-R-I-N-D-I-G-V-V-K-P-R-T-P-V-S-Y-R-E-L-A-K-M-P-E-H-L-R-K-Y-L-A-S-R-D-V-G-L-L-I-L-S-T-P-Q-G-V-M-T-H-R-E-A-L-K-R-K-I-G-G-I-V-I-A-Y-V-Y"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-A-K-D-V-H-V-V-E-R-V-E-V-P-E-G-V-T-V-S-I-D-G-M-R-V-K-V-S-G-P-K-G-E-V-E-R-D-F-S-H-A-R-G-V-L-I-R-L-E-D-N-S-V-V-V-E-S-F-F-A-K-A-R-Q-R-A-L-V-G-A-I-A-G-H-I-R-N-M-I-K-G-V-Q-G-G-F-R-Y-K-L-K-I-M-Y-S-H-F-P-I-N-V-K-V-E-G-D-K-F-I-I-S-N-F-L-G-E-K-G-L-R-I-A-R-I-M-P-G-V-K-V-Q-V-K-G-S-D-V-I-V-E-G-I-D-V-E-K-V-A-Q-T-A-A-N-I-E-L-A-T-K-V-K-D-K-D-R-R-K-F-M-D-G-I-Y-I-Y-E-R-E-V-I-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-D-Y-R-F-Q-R-R-L-A-A-E-I-L-G-V-G-E-S-R-I-W-I-S-P-D-P-E-L-R-E-E-I-E-G-A-V-T-K-A-D-V-R-A-L-I-K-R-G-V-I-K-V-L-P-E-K-G-N-A-G-H-A-S-K-V-R-H-L-Q-R-R-K-G-R-R-R-G-M-G-R-R-K-G-V-A-T-A-R-L-D-P-K-E-R-W-M-H-R-I-R-K-I-R-R-Y-L-R-Y-L-R-D-K-Q-V-I-D-R-K-T-Y-R-R-L-Y-M-L-A-K-G-G-T-F-R-D-L-A-S-L-K-R-Y-M-A-D-R-G-L-V-P-E-E-K-I-R"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-V-V-R-R-R-K-K-S-R-K-L-R-G-R-T-R-T-M-S-W-G-R-I-G-Q-H-R-K-S-G-S-K-G-G-Y-G-A-A-G-L-G-K-H-E-W-T-W-T-I-K-Y-A-P-T-W-Y-G-K-K-G-F-N-P-P-R-I-R-A-G-L-E-V-T-T-I-N-V-G-Q-L-D-E-I-A-A-L-L-E-A-Q-G-K-A-E-K-E-D-G-K-I-V-V-N-L-E-K-L-G-I-H-K-L-L-G-E-G-R-V-A-R-P-L-K-V-I-T-P-L-A-S-E-L-A-I-K-K-I-E-E-A-G-G-E-V-I-V-T-R-A-T-R-E-E-A-E-E-S"} +{"text": "### FUNCTION Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A ### SEQUENCE -M-S-V-A-L-S-I-P-L-L-S-L-P-E-D-M-R-E-A-L-A-A-A-A-G-P-V-Y-S-G-D-R-F-R-R-Q-L-L-Q-T-P-C-S-G-V-A-C-I-G-D-Y-V-S-Q-A-C-I-A-T-L-S-T-A-W-T-G-P-L-I-L-V-V-D-G-K-T-R-R-E-S-W-R-D-M-V-V-P-Q-G-F-R-V-H-R-V-R-S-P-P-G-S-L-S-L-E-A-Y-T-T-I-C-K-L-M-E-E-Y-G-R-H-V-V-F-V-E-G-E-E-D-L-I-A-L-A-A-L-D-C-G-I-D-W-T-V-V-Y-G-L-P-G-V-G-G-V-V-V-H-R-C-L-R-K-P-G-L-E-N-S-S-V-L-A-F-K-P-G-T-G-V-H-H-Q-S-S-P"} +{"text": "### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-K-P-E-E-V-I-I-R-V-Y-V-T-E-K-T-T-R-M-L-E-E-E-N-T-L-T-F-I-V-R-R-E-A-T-K-N-D-V-K-R-A-V-E-Q-L-F-G-V-K-V-E-K-V-R-T-L-I-T-P-R-G-Y-K-K-A-Y-V-K-L-A-P-E-Y-K-A-L-D-V-A-T-K-L-G-A-V"} +{"text": "### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-L-P-V-N-P-R-D-L-E-K-M-M-R-R-L-G-I-K-V-E-Q-L-S-A-D-E-A-R-I-V-L-G-S-G-E-T-M-V-F-R-S-P-T-V-I-V-M-R-A-K-G-Q-P-P-M-V-Y-L-V-G-D-Y-T-V-E-K-P-R-E-E-T-A-A-E-I-T-E-E-D-V-A-L-V-A-E-Q-A-G-V-S-M-E-E-A-R-K-A-L-E-E-S-G-G-D-I-A-E-A-I-L-R-L-K-G-E-E"} +{"text": "### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently ### SEQUENCE -M-Q-C-G-G-W-M-H-E-E-H-T-A-D-V-L-V-I-A-Y-G-R-T-L-E-E-A-F-E-N-A-A-R-G-V-Y-E-V-V-T-D-T-S-R-V-E-P-R-R-R-V-D-A-S-I-E-G-I-D-L-E-N-L-L-Y-R-F-I-E-N-L-I-A-Y-T-D-S-E-G-L-V-F-G-L-F-R-V-C-K-I-E-C-N-G-E-S-C-S-I-V-A-S-A-W-G-E-E-F-D-P-S-R-H-E-H-R-T-I-V-K-A-M-T-Y-A-D-M-E-I-K-E-E-N-G-C-W-R-V-Q-F-V-V-D-I"} +{"text": "### FUNCTION Probable zinc metalloprotease whose natural substrate is unknown ### SEQUENCE -M-E-S-S-L-T-F-L-L-L-P-V-G-F-P-G-E-V-L-V-T-L-A-R-R-A-R-E-A-M-P-V-P-S-L-W-L-A-S-T-D-P-L-E-P-P-I-E-A-Y-S-W-E-R-M-Q-F-D-A-E-K-V-N-E-H-I-H-S-V-L-Y-D-Y-V-R-E-G-I-R-I-I-G-V-V-D-A-D-G-Y-I-P-G-F-N-F-V-F-G-L-A-S-T-A-L-G-V-A-T-V-Y-T-R-R-L-K-T-G-G-N-G-L-Y-T-E-R-L-L-K-E-V-L-H-E-A-G-H-L-L-G-L-D-H-C-S-N-R-E-C-V-M-S-F-S-R-S-V-E-E-V-D-R-K-A-P-L-F-C-S-S-C-K-A-K-L-V-L-K-Y-G-S-R-G-Q"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-F-L-S-G-R-D-L-V-L-L-G-V-V-K-G-H-S-N-G-A-I-Q-P-A-G-V-D-L-S-V-G-E-I-E-S-L-A-D-A-G-F-L-G-E-E-D-K-I-M-P-K-G-D-R-I-Q-C-E-Y-G-V-C-E-L-E-P-G-A-Y-R-L-R-F-N-E-V-V-S-I-P-P-G-H-V-G-F-C-F-P-R-S-S-L-L-R-M-G-C-Y-L-G-C-A-V-W-D-P-G-Y-T-G-R-G-Q-A-M-L-L-V-A-N-P-H-G-L-R-L-E-M-G-S-R-I-A-Q-L-V-V-A-R-V-E-G-P-L-T-S-L-Y-K-G-D-Y-Q-G-E-G-L"} +{"text": "### FUNCTION Acts as a methyl group carrier between MtbB and MtbA ### SEQUENCE -T-L-Q-G-Q-K-D-V-I-E-L-L-K-E-E-G-L-R-D-K-I-K-V-M-V-G-G-A-P-A-T-Q-A-W-A-D-K-I-G-A-D-C-Y-A-E-N-A-S-E-A-V-A-K-A-K-E-L-L-A"} +{"text": "### FUNCTION Binds to muscle nicotinic acetylcholine receptor and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-R-C-F-N-H-P-S-S-Q-P-Q-T-N-K-S-C-P-P-G-E-N-S-C-Y-N-K-Q-W-R-D-H-R-G-T-I-I-E-R-G-C-G-C-P-T-V-K-P-G-I-K-L-T-C-C-Q-S-E-D-C-N-N"} +{"text": "### FUNCTION Binds to muscle nicotinic acetylcholine receptor and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-R-C-F-N-H-P-S-S-Q-P-Q-T-N-K-S-C-P-P-G-E-N-S-C-Y-N-K-Q-W-R-D-H-R-G-T-I-T-E-R-G-C-G-C-P-T-V-K-P-G-I-K-L-T-C-C-Q-S-E-D-C-N-N"} +{"text": "### FUNCTION Binds to muscle nicotinic acetylcholine receptor and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-M-V-C-L-D-L-G-Y-T-R-R-C-F-N-Q-Q-S-S-Q-P-K-T-T-K-S-C-P-L-G-E-N-S-C-Y-N-K-Q-W-R-D-H-R-G-S-I-T-E-R-G-C-G-C-P-K-V-K-P-G-I-K-L-R-C-C-E-S-E-D-C-N-N"} +{"text": "### FUNCTION Somatostatin inhibits the release of somatotropin ### SEQUENCE -M-Q-L-L-S-S-L-V-S-L-L-L-V-L-Y-S-V-R-A-A-A-V-L-P-V-E-E-R-N-P-A-Q-S-R-E-L-S-K-E-R-K-E-L-I-L-K-L-I-S-G-L-L-D-G-V-D-N-S-V-L-D-G-E-I-A-P-V-P-F-D-A-E-E-P-L-E-S-R-L-E-E-R-A-V-Y-N-R-L-S-Q-L-P-Q-R-D-R-K-A-P-C-K-N-F-F-W-K-T-F-T-S-C"} +{"text": "### FUNCTION Somatostatin inhibits the release of somatotropin ### SEQUENCE -M-L-S-T-R-I-Q-C-A-L-A-L-L-S-L-A-L-A-V-C-S-V-S-A-A-P-T-D-A-K-L-R-Q-L-L-Q-R-S-L-L-N-P-A-G-K-Q-E-L-A-R-Y-T-L-A-D-L-L-S-E-L-V-Q-A-E-N-E-A-L-E-P-E-D-L-S-R-A-V-E-K-D-E-V-R-L-E-L-E-R-A-A-G-P-M-L-A-P-R-E-R-K-A-G-C-K-N-F-F-W-K-T-F-T-S-C"} +{"text": "### FUNCTION Exhibits M2 muscarinic acetylcholine receptor -blocking activity, but has a weak binding activity toward nicotinic AChR Moreover, it inhibits collagen-induced platelet aggregation ### SEQUENCE -M-K-T-L-L-L-S-L-V-V-V-I-I-V-C-L-D-L-G-Y-T-M-Q-C-K-T-C-S-F-Y-T-C-P-N-S-E-T-C-P-D-G-K-N-I-C-V-K-R-S-W-T-A-V-R-G-D-G-P-K-R-E-I-R-R-E-C-A-A-T-C-P-P-S-K-L-G-L-T-V-F-C-C-T-T-D-N-C-Y-H"} +{"text": "### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-T-C-L-I-C-P-E-K-Y-C-N-K-V-H-T-C-L-N-G-E-K-I-C-F-K-K-Y-D-Q-R-K-L-L-G-K-G-Y-I-R-G-C-A-D-T-C-P-K-L-Q-N-R-D-V-I-F-C-C-S-T-D-K-C-N-L"} +{"text": "### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-S-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-T-C-L-I-C-P-E-K-Y-C-N-K-V-H-T-C-L-N-G-E-K-I-C-F-K-K-Y-D-Q-R-K-L-L-G-K-R-Y-I-R-G-C-A-D-T-C-P-V-R-K-P-R-E-I-V-E-C-C-S-T-D-K-C-N-H"} +{"text": "### FUNCTION Binds to muscle nicotinic acetylcholine receptor and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -M-K-T-L-L-L-T-L-L-V-V-T-I-V-C-L-D-L-G-Y-T-L-E-C-H-N-Q-Q-S-S-Q-A-P-T-T-T-G-C-S-G-G-E-T-N-C-Y-K-K-S-W-R-D-H-R-G-Y-R-I-E-R-G-C-G-C-P-S-V-K-K-G-I-E-I-N-C-C-T-T-D-R-C-N-N"} +{"text": "### FUNCTION Binds to muscle nicotinic acetylcholine receptor and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -M-K-T-L-L-L-T-L-L-V-V-T-I-V-C-L-D-L-G-Y-T-L-E-C-H-N-Q-Q-S-S-E-T-P-T-T-T-G-C-S-G-G-E-T-N-C-Y-K-K-S-W-R-D-H-R-G-Y-R-I-E-R-G-C-G-C-P-S-V-K-K-G-I-E-I-N-C-C-T-T-D-R-C-N-N"} +{"text": "### FUNCTION May act as a scaffolding protein within caveolar membranes Interacts directly with G-protein alpha subunits and can functionally regulate their activity ### SEQUENCE -M-G-L-E-K-E-K-L-E-C-S-I-I-M-D-E-D-E-F-N-R-S-I-E-P-I-L-S-K-K-A-R-L-Y-S-S-A-P-D-R-D-P-H-D-I-N-A-Q-L-K-V-G-F-E-D-V-I-A-E-P-A-S-A-H-S-F-D-R-V-W-I-G-S-S-A-T-F-E-L-V-K-F-I-F-Y-R-L-L-T-T-L-L-A-V-P-A-A-F-I-L-G-V-V-F-G-V-L-S-C-I-H-I-W-L-V-M-P-V-T-R-S-F-L-M-L-L-P-S-I-Q-V-V-W-K-S-V-T-D-M-F-I-T-P-L-F-H-S-M-G-R-S-L-S-S-I-Q-V-R-T-S-D-T"} +{"text": "### FUNCTION Binds to muscle nicotinic acetylcholine receptor and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-R-C-F-N-Q-Q-S-S-E-P-Q-T-N-K-S-C-P-P-G-E-N-S-C-Y-N-K-Q-W-R-D-H-R-G-T-I-I-E-R-G-C-G-C-P-Q-V-K-S-G-I-K-L-T-C-C-Q-S-D-D-C-N-N"} +{"text": "### FUNCTION Binds to muscle nicotinic acetylcholine receptor and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-R-C-F-N-Q-Q-S-S-E-P-Q-T-N-K-S-C-P-P-G-E-N-S-C-Y-N-K-Q-W-R-D-H-R-G-T-I-T-E-R-G-C-G-C-P-Q-V-K-S-G-I-K-L-T-C-C-Q-S-D-D-C-N-N"} +{"text": "### FUNCTION Binds to muscle nicotinic acetylcholine receptor and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-T-V-C-L-D-L-G-Y-T-R-R-C-F-N-Q-Q-S-S-Q-P-K-T-T-K-S-C-P-L-G-E-N-S-C-Y-N-K-Q-W-R-D-H-R-G-S-I-T-E-R-G-C-G-C-P-K-V-K-P-G-I-K-L-R-C-C-E-S-E-D-C-N-N"} +{"text": "### FUNCTION Binds to muscle nicotinic acetylcholine receptor and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-R-C-F-N-Q-Q-S-S-E-P-Q-T-N-K-S-C-P-P-G-E-N-S-C-Y-R-K-Q-W-R-D-H-R-G-T-I-I-E-R-G-C-G-C-P-T-V-K-P-G-I-K-L-R-C-C-E-S-E-D-C-N-N"} +{"text": "### FUNCTION Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX ### SEQUENCE -R-K-L-A-F-R-Y-R-R-V-K-E-L-Y-N-T-Y-K-N-N-I-G-G-L-L-G-P-A-K-R-D-A-W-L-Q-L-R-A-E-I-E-A-L-T-D-S-W-L-T-N-A-L-K-S-L-S-I-I-S-T-R-S-N-C-V-N-V-L-V-T-T-T-Q-L-I-P-A-L-A-K-V-L-L-Y-S-L-G-G-A-F-P-I-E-N-I-Y-S-A-T-K-I-G-K-E-S-C-F-E-R-I-V-S-R-F-G-T-N-I-T"} +{"text": "### FUNCTION Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX ### SEQUENCE -R-K-L-A-F-R-Y-R-R-V-K-E-L-Y-T-T-Y-K-N-N-V-G-G-L-L-G-P-A-K-R-D-A-W-L-Q-L-R-A-E-V-E-A-L-T-D-S-W-L-T-H-A-L-K-S-L-S-I-I-S-S-R-S-N-C-V-N-V-L-V-T-T-T-Q-L-I-P-A-L-A-K-V-L-L-Y-S-L-G-A-V-F-P-I-E-N-I-Y-S-A-T-K-I-G-K-E-S-C-F-E-R-I-V-S-R-F-G-T-N-I-T"} +{"text": "### FUNCTION Plays an essential role in viral DNA replication ### SEQUENCE -M-T-N-V-W-F-A-T-D-V-N-L-I-N-C-V-L-K-D-N-L-F-L-I-D-N-N-Y-I-I-L-N-V-F-D-Q-E-T-D-Q-V-R-P-L-C-L-G-E-I-N-A-L-Q-T-D-A-A-A-Q-A-D-A-M-L-D-T-S-S-T-S-E-L-Q-S-N-A-S-T"} +{"text": "### FUNCTION Involved in late/very late gene activation ### SEQUENCE -M-A-P-A-V-V-G-A-S-Q-L-R-G-G-D-S-P-G-P-A-R-N-R-D-H-C-L-N-R-S-E-V-Y-A-L-T-R-E-A-I-N-K-R-K-H-L-G-D-V-K-G-V-C-A-H-L-F-D-D-S-F-S-A-Q-S-D-Y-I-R-E-N-L-A-T-A-F-I-V-V-G-D-N-C-R-E-R-K-H-L-G-Q-H-A-A-R-F-D-R-V-F-S-L-K-R-R-T-L-Y-D-E-Y-H-A-S-A-G-R-Y-G-D-T-K-P-C-R-K-R-R-F-S-R-A-A-Q-V-R-D-Q-P-A-Q-Q-E-R-L-G-D-Q-S-V-Q-D-S-P-L-R-K-E-K-D-L-V-P-H-Q-G-V-G-G-V-R-P-G-Q-E-N-G-Q-A-R-Q-E-E-Q-S-Q-Q"} +{"text": "### FUNCTION Capsid protein self-assembles to form a quasi-spherical capsid, about 26 nm, or bacilliform ### SEQUENCE -M-S-S-A-A-Q-P-M-S-R-R-A-R-R-R-A-A-R-R-A-L-G-S-Q-P-G-T-S-G-G-M-V-I-P-V-S-F-V-V-S-G-A-T-S-A-D-F-V-T-Y-H-S-L-Y-S-R-L-A-A-Y-N-G-D-L-W-I-R-R-V-A-V-R-V-T-G-S-V-A-K-R-M-G-K-Y-A-F-F-E-G-L-A-V-D-K-S-Q-I-L-S-A-A-H-A-R-P-Y-V-Y-G-L-P-S-T-L-S-L-P-G-G-R-R-Q-V-K-D-F-Q-S-I-N-L-F-F-L-L-D-G-T-A-H-A-G-E-F-A-A-G-T-F-Y-F-E-F-E-G-S-P-N-V-D-F-P-R-D-S-E-G-S-N-Q-A-V-E-K-F-Y-L-E-H-I-N-A"} +{"text": "### FUNCTION Pathogenicity determinant , a mechanism of plant viral defense that limits the accumulation of viral RNAs ### SEQUENCE -M-K-M-E-N-L-I-S-M-F-C-F-S-S-K-G-S-S-K-R-R-T-K-G-S-S-T-W-F-P-Q-P-D-Q-H-I-T-I-R-T-F-R-R-L-K-A-H-Q-M-L-S-H-T-W-T-K-T-E-T-S-L-T-M-E-V-S-K-S-M-A-D-Q-L-E-E-V-N-S-L-P-T-T-L-M-P-R-H-S-I-V-D-P-S-Y-R-P-S-I-Y"} +{"text": "### FUNCTION Increases viral DNA accumulation Enhances infectivity and symptom expression ### SEQUENCE -M-D-F-R-T-G-D-N-I-T-A-A-Q-L-K-N-G-V-F-I-W-E-V-R-N-P-L-S-F-K-I-M-Q-H-R-Q-I-R-P-G-S-Q-M-Y-V-T-Q-I-R-I-M-F-N-H-G-L-K-K-A-L-L-M-H-K-C-F-L-D-L-T-L-Y-H-Y-L-T-A-T-S-G-M-I-L-S-T-F-S-D-Q-L-F-R-Y-L-N-N-L-G-V-I-S-I-G-N-V-L-K-G-A-S-H-I-L-Y-E-K-L-H-H-V-E-D-V-S-L-T-H-N-V-Q-Y-K-L-Y"} +{"text": "### FUNCTION Through its interaction with host SGS3, acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing , a mechanism of plant viral defense that limits the accumulation of viral RNAs ### SEQUENCE -M-W-D-P-L-V-N-D-F-P-K-S-L-H-G-F-R-C-M-L-A-I-K-Y-L-Q-Y-I-Q-E-N-Y-P-S-N-S-L-G-F-V-Y-L-T-E-L-I-Q-V-L-R-I-R-K-H-A-K-A-E-L-R-Y-R-L-L-Y-P-D-V-E-C-A-E-E-A-D-L-R-H-P-A-F-L-T-C-H-C-G-K-C-P-C-Q-R-E-K-E-E-V-D-Q-P-T-H-V-E-E-T-E-I-L-S-V-I-P-L-S"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-S-F-D-S-G-C-P-P-T-P-P-V-K-L-L-F-K-K-H-S-P-F-A-V-T-P-Q-R-A-T-S-G-A-A-G-Y-D-L-C-S-S-A-D-V-V-V-P-P-K-S-R-S-L-I-P-T-D-L-S-F-Q-F-P-R-G-V-Y-G-R-I-A-P-R-S-G-L-A-V-K-F-F-I-D-V-G-A-G-V-I-D-S-D-Y-R-G-I-V-S-V-L-L-F-N-F-S-D-H-N-F-N-V-R-R-G-D-R-I-A-Q-L-I-L-E-R-H-L-T-P-D-L-E-E-R-S-G-L-D-E-T-A-R-G-A-A-G-F-G-S-T-G-G-F-D-T-G-V-C-P-S-S-F-S"} +{"text": "### FUNCTION May transport viral genome to neighboring plant cells directly through plasmosdesmata, without any budding The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier ### SEQUENCE -M-A-D-P-V-Y-Y-Q-G-Y-Q-D-D-G-D-I-D-A-Q-K-R-H-Q-A-L-Y-L-I-G-I-I-I-L-I-M-V-C-I-I-I-L-W-V-C-I-M-L-A-C-Y-I-P-G-F-L-K-K-T-M-E-A-W-L-S-S-S-S-M-M-K-R-R-V-A-A-T-I-T-R-T-P-F-E-A-T-G-P-E-R-E-R-N-W-D-A-R-R-Q-T-N-A-A-S-S-Q-P-S-N-G-G-V-F"} +{"text": "### FUNCTION Putative nuclear shuttle protein ### SEQUENCE -M-A-D-W-F-A-S-P-L-K-T-C-T-H-V-C-D-F-P-T-L-A-G-D-P-S-Q-E-I-T-C-C-D-S-M-K-N-K-L-N-D-S-R-K-V-L-L-V-S-C-S-V-S-F-N-G-S-F-Y-G-G-N-R-N-V-R-G-Q-L-Q-I-S-M-L-E-D-D-G-V-C-R-P-I-G-Y-V-P-I-G-G-Y-L-Y-H-N-D-Y-G-Y-Y-E-G-E-K-T-F-N-L-D-I-E-S-Q-Y-L-K-K-D-E-D-Y-N-R-K-F-I-V-S-V-L-N-E-N-G-L-D-S-L-C-D-L-K-V-F-I-V-H-A-L-R-I-K-V"} +{"text": "### FUNCTION Interacts with and disrupts the function of host retinoblastoma-related proteins RBR, which are key regulators of the cell cycle Induces transcriptional activation of E2F-regulated S-phase and G2/M-phase-specific genes Inactivation of the ability of RBR to arrest the cell cycle leads to the stimulation of viral DNA replication ### SEQUENCE -M-G-L-K-Y-F-A-H-L-P-L-E-L-R-E-K-I-V-R-D-H-L-Q-E-E-R-K-K-E-F-L-E-K-A-I-E-D-S-C-R-R-H-E-A-L-L-I-E-D-P-S-P-A-E-L-N-S-L-S-K-F-L-T-A-L-S-D-Y-V-G-N-Q-F-N-T-R-C-L-I-R-W-K-K-D-V-P-S-K-V-K-F-G-F-M-D-E-Q-H-H-K-L-Y-G-S-M-D-M-D-D-L-S-C-G-E-L-F-I-P-D-E-E-D-D-L-T-Y-E-D-G-V-I-V-R-C-S-Q-L-D-Q-L-F-K-S-L-G-I-E-I-V-Y-I-V-V-S-K-H-C-I-W-A-P-L-S-K-E-I-V-I-K"} +{"text": "### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins ### SEQUENCE -M-C-H-T-S-C-S-S-G-C-Q-P-S-C-C-V-S-S-S-C-Q-P-S-C-C-V-S-S-P-C-Q-A-S-C-F-V-S-S-P-C-Q-P-S-C-C-V-S-S-S-C-Q-S-A-C-C-R-P-A-I-C-I-P-V-R-Y-Q-V-A-C-C-V-P-V-S-C-G-P-T-V-C-M-A-P-S-C-Q-S-S-V-C-V-P-V-S-C-R-P-V-C-V-T-S-S-C-Q-S-S-G-C-C-Q-P-S-C-P-T-L-V-C-K-P-V-T-C-S-N-P-S-C-C"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-I-E-S-I-S-G-N-I-H-D-L-P-G-E-D-L-E-D-V-H-V-E-S-V-V-L-P-L-A-D-L-T-K-R-I-Q-R-V-R-S-D-H-G-T-E-L-G-I-R-L-A-P-G-A-P-D-L-R-E-G-D-I-L-L-R-N-E-R-G-I-V-V-V-R-L-E-P-T-D-V-L-V-I-A-P-V-T-V-R-E-M-G-V-V-A-H-N-L-G-N-R-H-L-P-A-Q-F-F-G-P-A-E-P-F-P-G-L-E-G-H-D-G-V-M-V-I-Q-Y-D-H-T-A-E-H-Y-L-E-H-L-G-V-R-H-A-R-M-E-R-S-M-P-V-P-F-R-H-A-E-H-T-H"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-L-P-A-Q-K-H-V-W-V-G-L-Q-S-I-Y-G-I-G-R-T-R-S-K-K-L-C-E-S-A-G-V-T-S-T-T-K-I-R-D-L-S-E-P-E-I-E-R-L-R-A-E-V-G-K-Y-V-V-E-G-D-L-R-R-E-I-G-I-A-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-H-P-L-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-K-A-I-R-K"} +{"text": "### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-I-E-P-L-L-C-G-I-V-L-G-L-I-P-I-T-L-A-G-L-F-M-A-A-Y-L-Q-Y-R-R-G-N-Q-L-G-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-A-Y-A-I-I-E-A-S-G-K-Q-L-W-V-E-P-G-R-F-Y-D-L-D-R-L-D-A-D-L-D-Q-S-L-T-L-D-K-V-L-L-V-Q-D-E-G-A-P-Q-I-G-Q-P-Y-V-A-G-A-T-V-Q-V-T-V-L-S-H-P-R-G-R-K-V-T-V-Y-K-M-K-P-K-K-K-T-R-K-K-Q-G-H-R-Q-D-L-T-R-V-L-V-E-S-I-T-V-G-G-K-V-L-T-A-N-A-A-D-L-P-K-S-E-A-D-I-D-A-A-G"} +{"text": "### FUNCTION Seems to affect the transcription of cya3 May be negatively autoregulated ### SEQUENCE -M-A-D-E-S-N-T-G-S-I-A-A-A-V-A-P-N-A-D-V-K-A-P-A-A-K-K-K-R-S-P-R-R-Q-K-A-V-A-E-P-R-R-A-V-S-E-T-P-A-A-K-P-R-R-Y-S-E-Q-Q-R-K-E-K-L-K-L-I-E-T-Q-V-T-E-G-K-V-T-L-K-D-A-I-K-S-A-G-I-S-E-Q-T-Y-Y-Q-W-K-R-T-V-K-P-V-E-Q-K-A-E-K-R-L-P-T-G-E-E-L-A-D-L-V-R-L-E-E-E-N-Q-R-L-R-K-L-L-A-E-K-L-R-A-E-N-A-D-L-R-K-R-L-G-L-D"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-P-A-R-E-I-T-I-I-N-K-L-G-L-H-A-R-A-A-A-K-F-V-G-V-A-G-R-F-P-C-Q-V-P-V-G-R-A-P-D-K-L-V-D-G-K-S-I-M-A-V-M-M-L-A-A-G-K-G-T-Q-V-H-L-H-T-X-G-E-Q-D-S-D-A-M-D-A-L-V-E-L-I-N-N-F-F-D-E-G-E"} +{"text": "### FUNCTION Regulates the transcription of the pyrimidine nucleotide operon in response to exogenous pyrimidines ### SEQUENCE -M-S-L-P-N-P-A-D-L-I-R-Q-M-A-V-D-L-R-A-H-L-A-R-R-A-I-T-E-P-R-Y-I-G-I-R-T-G-G-V-W-V-A-Q-A-L-Q-E-A-M-G-D-S-S-P-M-G-T-L-D-V-S-F-Y-R-D-D-F-S-Q-N-G-L-H-P-Q-V-R-P-S-E-L-P-F-E-V-E-G-Q-H-L-V-L-V-D-D-V-L-M-S-G-R-T-I-R-A-A-L-N-E-L-F-D-Y-G-R-P-A-S-V-T-L-V-C-L-L-D-L-D-A-G-E-L-P-I-R-P-N-V-L-G-A-T-L-S-L-A-A-H-E-R-V-K-L-T-G-P-A-P-L-A-L-E-R-Q-D-L-A-S-R-S-A-L"} +{"text": "### FUNCTION Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'--3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism ### SEQUENCE -M-E-T-L-N-F-Q-F-P-A-A-E-P-G-R-G-R-T-L-V-G-C-V-S-S-G-D-L-E-V-L-I-E-P-G-T-A-G-S-L-Q-I-Q-V-I-T-S-V-N-G-S-A-A-R-W-A-Q-L-F-Q-R-L-F-E-G-R-A-W-P-A-V-N-I-D-I-H-D-F-G-A-T-P-G-V-V-R-L-R-L-E-Q-G-F-E-E-I-A-H-D"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-F-K-P-L-H-D-R-V-L-V-R-R-V-Q-S-D-E-K-T-K-G-G-L-I-I-P-D-S-A-K-E-K-P-A-E-G-E-I-T-S-V-G-E-G-A-R-K-D-S-G-E-L-I-A-P-A-V-K-A-G-D-R-V-L-F-G-K-W-S-G-T-E-V-T-V-D-G-E-E-L-L-I-M-K-E-S-D-I-L-G-I-I-A"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-A-L-T-L-Q-I-I-L-V-V-A-S-L-L-M-T-V-F-V-L-L-H-K-G-K-G-G-G-L-S-S-L-F-G-G-G-V-Q-S-N-L-S-G-S-T-V-V-E-K-N-L-D-R-V-T-I-L-V-A-V-I-W-I-V-C-I-V-A-L-N-L-I-Q-T-Y-S"} +{"text": "### FUNCTION Component of the sil cation-efflux system that confers resistance to silver ### SEQUENCE -M-K-N-I-V-L-A-S-L-L-G-F-G-L-I-S-S-A-W-A-T-E-T-V-N-I-H-E-R-V-N-N-A-Q-A-P-A-H-Q-M-Q-S-A-A-A-P-V-G-I-Q-G-T-A-P-R-M-A-G-M-D-Q-H-E-Q-A-I-I-A-H-E-T-M-T-N-G-S-A-D-A-H-Q-K-M-V-E-S-H-Q-R-M-M-G-S-Q-T-V-S-P-T-G-P-S-K-S-L-A-A-M-N-E-H-E-R-A-A-V-A-H-E-F-M-N-N-G-Q-S-G-P-H-Q-A-M-A-E-A-H-R-R-M-L-S-A-G"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-V-A-C-C-H-R-A-P-V-V-H-R-R-S-S-E-S-E-E-V-G-P-A-V-V-L-G-F-S-I-A-L-I-V-F-S-L-L-L-M-L-L-V-L-M-H-K-G-K-G-G-G-L-S-D-M-F-G-G-G-M-Q-S-S-V-G-G-S-S-V-A-E-R-N-L-D-R-I-T-V-V-V-G-L-A-W-F-A-C-I-M-V-L-G-L-L-M-K-A-N-N"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-D-N-A-R-A-K-R-L-A-D-L-I-R-E-V-V-A-Q-K-L-Q-R-G-I-K-D-P-R-L-G-S-H-V-T-I-T-D-T-R-V-T-G-D-L-R-E-A-T-V-F-Y-T-V-Y-G-D-D-E-E-R-K-A-A-T-A-G-L-E-S-A-K-G-I-L-R-S-E-V-G-K-A-A-G-V-K-F-T-P-T-L-T-F-V-M-D-A-L-P-D-T-A-R-N-I-E-D-L-L-D-K-A-R-Q-S-D-E-K-V-R-E-A-S-A-G-A-T-Y-A-G-E-A-D-P-Y-R-K-P-D-E-D-E-T-D-T-E-G-A-V-E-A-D-E-T-D-D-T-A-K"} +{"text": "### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-F-R-G-F-K-E-F-L-S-R-G-N-I-V-D-L-A-V-A-V-V-I-G-T-A-F-T-A-L-I-T-K-F-T-D-S-I-I-T-P-L-I-N-R-V-G-V-N-Q-Q-T-N-I-S-P-L-R-I-D-I-G-G-D-Q-A-I-D-L-N-I-V-L-S-A-A-I-N-F-L-L-I-A-L-V-V-Y-F-L-V-V-L-P-Y-T-T-I-R-K-H-G-E-V-E-Q-F-D-T-D-L-I-G-N-Q-V-V-L-L-A-E-I-R-D-L-L-A-Q-S-N-G-A-P-S-G-R-H-V-D-T-A-D-L-T-P-T-P-N-H-E-P-R-A-D-T"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-D-Q-A-R-A-R-R-L-A-K-R-I-C-T-I-V-A-S-A-I-E-F-E-I-K-D-P-G-L-D-G-V-T-I-V-D-V-K-V-T-A-D-L-H-D-A-T-V-F-Y-T-V-M-G-R-T-L-E-D-A-P-D-Y-T-A-A-T-A-A-L-N-R-A-K-G-T-L-R-S-K-V-G-A-G-T-G-V-R-F-T-P-T-L-T-F-I-R-D-T-T-S-D-S-V-A-R-M-E-E-L-L-A-R-A-R-A-A-D-A-D-V-A-Q-V-R-L-R-A-K-P-A-G-E-A-D-P-Y-R-D-K-G-S-V-A-G-L-V-G-V-D-I-A-D-I-D-D-D-D-L-T-D-D"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-N-T-G-L-P-S-Q-I-Q-V-I-E-L-L-G-G-E-V-A-R-A-G-Y-E-V-E-D-V-I-I-H-T-W-S-Q-P-F-W-I-T-V-L-A-D-G-D-T-V-L-A-R-D-I-I-A-T-L-S-H-S-V-S-A-L-L-D-G-L-D-N-I-V-D-R-Y-F-L-E-V-S-S-L-G-M-G-R-P-F-T-S-E-K-H-F-R-R-A-R-G-R-K-V-E-L-A-A-V-G-R-I-P-A-D-R-S-N-W-G-D-V-R-R-H-G-D-V-G-D-P-R-R-P-R-L-C-G-M-R-D-P-A-I-E-I-M-K-A-I-V"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-P-Q-A-K-K-R-I-R-R-N-D-R-R-A-E-I-N-G-N-R-V-N-R-I-R-T-F-I-K-K-V-E-S-A-I-A-A-G-N-K-S-E-A-E-T-A-L-A-S-A-Q-P-E-L-F-R-G-V-S-K-G-V-L-H-K-N-T-A-S-R-K-F-S-R-L-A-K-G-V-A-A-L-A"} +{"text": "### FUNCTION Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA Also appears to be involved in tRNA biosynthesis ### SEQUENCE -L-Q-E-I-F-R-G-V-R-K-A-V-K-S-H-G-C-K-R-A-I-L-V-G-H-N-S-S-F-D-L-A-F-L-N-A-A-V-A-R-C-D-I-K-R-N-P-F-H-P-F-S-S-F-D-T-A-T-L-A-G-L-A-Y-G-Q-T-V-L-A-K-A-C-Q-S-A-G-I-E-F-D-G-R-E-A-H-S-A-R-Y-D-T-E-K-T-A-E-L-F-C-G-I-V-N-R-W-K-E-M-G-G-W-V-D-F-A"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-S-A-L-T-R-Q-L-E-E-F-R-R-C-S-T-A-E-Q-Y-F-E-L-L-D-V-D-Y-D-P-R-V-V-A-V-N-R-L-H-I-L-R-Y-F-A-E-E-I-A-G-L-H-E-G-A-D-A-E-V-S-P-E-V-L-L-R-D-Y-R-A-A-L-I-R-A-Y-E-A-F-T-T-A-T-G-L-D-H-R-L-F-K-V-L-K-D-R-A-P-E-P-A-G-F-V-A-T-T-D-I-T-V-E-R-P-A-T-A-Q-S-D-E-K-G-Q-D-R"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-N-N-I-K-L-S-I-L-T-P-Q-K-T-F-Y-V-G-D-V-K-E-I-I-T-R-T-V-E-G-E-I-G-I-L-P-N-H-T-D-L-V-A-F-L-T-P-T-E-T-I-L-V-E-E-D-G-S-R-K-K-V-F-T-S-T-G-I-L-N-V-G-E-S-E-V-S-F-M-C-D-A-S-E-W-P-D-E-I-D-I-Q-R-A-E-T-A-K-E-R-A-E-K-R-L-K-T-S-N-N-I-D-V-K-R-A-E-L-S-L-S-R-A-L-A-R-I-K-T-K-N-D"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-Y-E-F-L-D-R-R-Y-A-L-A-L-Y-E-V-G-E-K-N-Q-K-L-E-E-Y-I-N-D-F-G-E-I-V-H-L-L-K-N-D-E-N-I-N-Q-V-V-N-H-P-Q-I-S-T-S-E-K-K-K-I-F-M-E-I-F-K-G-K-I-D-E-K-L-L-N-F-L-L-L-L-L-E-K-K-R-I-H-D-A-E-G-I-L-T-Q-L-N-K-I-S-L-E-K-H-N-K-V-V-A-E-V-R-T-V-I-P-L-T-D-N-E-K-T-T-L-A-S-K-L-S-A-K-Y-N-K-I-I-I-F-K-E-I-I-D-K-T-I-I-G-G-V-Y-V-R-V-G-D-D-V-I-D-G-T-I-K-F-K-L-E-S-M-K-K-V-M-L-K-E-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-S-V-E-P-R-K-I-L-P-D-P-K-F-G-S-E-L-L-A-K-F-I-N-V-L-M-V-D-G-K-K-S-T-A-E-S-I-I-Y-G-A-L-E-T-L-S-Q-R-T-G-K-E-A-L-E-A-F-E-A-A-L-E-N-V-R-P-T-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-P-A-R-R-N-A-L-A-M-R-W-I-V-E-A-A-R-K-R-G-D-K-S-M-A-L-R-L-A-N-E-L-S-D-A-A-D-N-K-G-T-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-N-Q-L-V-R-K-P-R-V-K-K-V-V-K-S-N-V-P-A-L-E-A-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-I-R-L-T-N-G-F-E-V-I-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-A-L-D-C-A-G-V-K-D-R-K-Q-G-R-S-K-Y-G-V-K-R-P-K-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-D-K-G-T-K-E-E-I-T-K-K-F-Q-L-H-E-K-D-T-G-S-A-D-V-Q-I-A-I-L-T-E-H-I-A-E-L-K-E-H-L-K-R-S-P-K-D-Q-N-S-R-L-A-L-L-K-L-V-G-Q-R-R-K-L-L-E-Y-L-N-S-T-D-T-E-R-Y-K-N-L-I-T-R-L-N-L-R-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-A-T-G-S-V-A-S-R-R-R-R-K-R-I-L-K-Q-A-K-G-F-W-G-D-R-K-G-H-I-R-Q-S-R-S-S-V-M-R-A-M-A-F-N-Y-M-H-R-K-D-R-K-G-D-F-R-S-L-W-I-A-R-L-N-V-A-S-R-I-H-S-L-S-Y-S-R-L-I-N-G-L-K-C-A-N-I-S-L-N-R-K-M-L-S-E-I-A-I-H-N-P-E-G-F-A-E-I-A-N-Q-A-K-K-A-L-E-A-T-V"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-A-L-N-F-K-I-N-R-Q-I-R-A-P-K-V-R-L-I-G-S-A-G-E-Q-L-G-I-L-A-I-K-D-A-L-D-L-A-R-E-A-G-L-D-L-V-E-V-A-S-N-S-E-P-P-V-C-K-I-M-D-Y-G-K-Y-R-Y-G-L-T-K-K-E-K-D-S-K-K-A-Q-H-Q-V-R-I-K-E-V-K-L-K-P-N-I-D-E-N-D-F-S-T-K-L-K-Q-A-R-T-F-V-E-K-G-N-K-V-K-I-T-C-M-F-R-G-R-E-L-A-Y-P-E-H-G-F-K-V-V-Q-K-M-S-Q-G-L-E-D-I-G-F-V-E-A-E-P-K-L-A-G-R-S-L-I-C-V-V-A-P-G-T-V-K-T-K-K-K-Q-E-K-S-H-A-Q-D-E-N-Q"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-A-T-L-S-P-E-K-F-S-G-S-P-I-S-I-S-K-E-F-P-Q-Q-K-M-R-E-I-I-L-Q-M-L-Y-A-L-D-M-A-P-S-A-E-D-S-L-V-P-L-L-M-S-Q-T-A-V-S-Q-K-H-V-L-V-A-L-N-Q-T-K-S-I-L-E-K-S-Q-E-L-D-L-I-I-G-N-A-L-K-N-K-S-F-D-S-L-D-L-V-E-K-N-V-L-R-L-T-L-F-E-H-F-Y-S-P-P-I-N-K-A-I-L-I-A-E-A-I-R-L-V-K-K-F-S-Y-S-E-A-C-P-F-I-Q-A-I-L-N-D-I-F-T-D-S-S-L-N-E-N-S-L-S-I"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-Q-Q-L-L-L-L-E-D-V-D-G-L-G-R-S-G-D-L-I-T-A-R-P-G-Y-V-R-N-Y-L-I-P-K-K-K-A-V-I-A-G-A-G-T-L-R-L-Q-A-K-L-K-E-Q-R-L-I-Q-A-A-A-D-K-A-D-S-E-R-I-A-Q-A-L-K-D-I-V-L-E-F-Q-V-R-V-D-P-D-N-N-M-Y-G-S-V-T-I-A-D-I-I-A-E-A-A-K-K-N-I-F-L-V-R-K-N-F-P-H-A-H-Y-A-I-K-N-L-G-K-K-N-I-P-L-K-L-K-E-E-V-T-A-T-L-L-V-E-V-T-S-D-N-E-Y-V-T-V-L-A-Q-G-K-Q-T-E-E-N-Q-E-G"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-N-K-P-V-H-N-N-E-H-R-R-K-R-F-N-K-K-C-P-F-V-S-A-G-W-K-T-I-D-Y-K-D-V-E-T-L-K-K-F-I-T-E-R-G-K-V-L-P-R-R-I-T-G-V-S-S-R-F-Q-G-V-L-S-Q-A-I-K-R-A-R-H-L-G-L-L-P-F-V-G-E-D"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-G-K-K-E-N-Q-L-Y-E-G-A-Y-V-F-S-V-T-L-S-E-E-A-R-R-K-A-L-D-K-V-I-S-G-I-T-N-Y-G-G-E-I-H-K-I-H-D-Q-G-R-K-K-L-A-Y-T-I-R-G-A-R-E-G-Y-Y-Y-F-I-Y-F-S-V-S-P-G-A-I-T-E-L-W-K-E-Y-H-L-N-E-D-L-L-R-F-M-T-L-R-A-D-S-V-K-E-V-L-E-F-A-S-L-P-E"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-A-K-L-I-V-A-I-G-N-P-R-H-G-Y-A-N-T-R-H-N-A-G-F-L-L-A-D-R-L-V-E-E-L-Q-G-P-P-F-K-P-L-S-K-C-H-A-L-M-T-L-V-E-S-S-S-G-P-L-V-F-I-K-P-T-T-F-V-N-L-S-G-K-A-V-V-L-A-K-K-Y-F-N-V-A-L-S-H-I-L-V-L-A-D-D-V-N-R-S-F-G-K-L-R-L-C-F-N-G-G-S-G-G-H-N-G-L-K-S-I-T-A-S-L-G-S-N-E-Y-W-Q-L-R-F-G-V-G-R-P-L-E-E-G-V-E-L-S-N-F-V-L-G-K-F-S-E-E-E-N-L-Q-L-G-S-I-F-V-E-A-S-T-L-F-T-E-W-C-S-K-F"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-E-L-V-V-T-S-R-E-T-G-K-K-S-F-L-K-K-I-R-Q-Q-G-G-I-P-A-V-V-Y-S-A-G-K-S-L-A-N-I-T-V-D-A-L-V-F-K-K-F-L-S-N-L-E-S-G-A-L-S-S-T-V-F-S-L-S-Y-E-G-R-I-I-K-A-L-V-K-D-I-Q-Y-Q-I-T-T-Y-D-V-I-H-L-D-F-E-E-L-V-E-D-R-P-V-K-L-N-I-P-I-R-C-I-N-A-V-D-C-I-G-V-K-L-G-G-S-L-R-Q-V-I-R-A-V-R-V-V-C-K-P-K-D-I-V-P-F-L-E-L-D-V-R-S-V-G-L-S-Q-T-R-K-L-S-D-I-K-I-P-A-G-I-E-T-I-T-P-L-K-E-V-A-I-T-V-S-R-R"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-S-V-A-R-E-A-K-R-R-R-L-V-E-A-N-F-K-K-R-S-D-L-R-K-I-V-K-S-L-S-V-S-E-E-E-K-E-N-A-R-I-S-L-N-K-M-K-R-D-T-S-P-T-R-L-H-N-R-C-L-L-T-G-R-P-R-G-Y-L-R-K-F-A-I-S-R-I-C-F-R-Q-M-A-S-M-G-E-I-P-G-V-I-K-A-S-W"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-H-P-L-T-L-P-K-Q-S-R-V-L-K-R-K-Q-F-L-Y-I-T-R-S-G-F-C-C-R-G-S-Q-A-T-F-Y-V-V-P-S-R-H-P-G-T-C-R-M-G-I-T-V-S-K-K-F-G-K-A-H-E-R-N-S-F-K-R-V-V-R-E-V-F-R-H-V-R-H-Q-L-P-N-C-Q-I-V-V-F-P-K-G-H-K-Q-R-P-V-F-S-K-L-L-Q-D-F-I-N-Q-I-P-E-G-L-H-R-L-G-K-T-K-A-T-T-G-G-E-C-T-P-K-S-E-K-C-V-T-A-P-R"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-R-V-S-T-S-E-F-R-V-G-L-R-I-E-I-D-G-Q-P-Y-L-I-L-Q-N-D-F-V-K-P-G-K-G-Q-A-F-N-R-I-K-V-K-N-F-L-T-G-R-V-I-E-R-T-Y-K-S-G-E-S-V-E-T-A-D-I-V-E-R-S-M-R-L-L-Y-T-D-Q-E-G-A-T-F-M-D-D-E-T-F-E-Q-E-V-V-F-W-E-K-L-E-N-I-R-Q-W-L-L-E-D-T-I-Y-T-L-V-L-Y-N-G-D-V-V-A-V-E-P-P-I-F-M-E-L-S-I-A-E-T-A-P-G-V-R-G-D-T-A-S-G-R-V-L-K-P-A-V-T-N-T-G-A-K-I-M-V-P-I-F-I-D-E-G-E-L-V-K-V-D-T-R-T-G-S-Y-E-S-R-V-S-K"} +{"text": "### FUNCTION Might have a role analogous to that of eukaryotic histone proteins ### SEQUENCE -M-A-L-K-D-T-A-K-K-M-K-D-L-L-D-S-I-Q-H-D-L-A-K-A-E-K-G-N-K-A-A-A-Q-R-V-R-T-D-S-I-K-L-E-K-V-A-K-L-Y-R-K-E-S-I-K-A-E-K-S-G-L-L-K-R-K-P-S-T-K-A-P-A-K-V-K-K-T-A-E-K-K-A-P-K-K-S-S-A-A-A-A-K-T-S-K-A-V-K-A-S-K-P-A-S-K-K-T-A-A-K-K-V-K-K-P-S-K-A-R-G-F-R-K"} +{"text": "### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-L-S-R-I-V-T-C-F-L-F-L-L-S-S-L-P-L-F-A-E-E-E-A-A-Q-S-K-N-T-F-V-Q-P-A-V-M-L-A-I-A-I-L-F-F-Y-F-I-L-W-R-P-E-Q-K-R-R-K-A-M-E-K-R-K-N-D-L-A-K-G-D-K-V-T-A-M-G-I-I-G-T-V-D-D-I-R-E-H-T-V-I-L-N-I-A-S-G-K-V-E-V-L-K-G-A-I-S-E-I-L-K-P-N-D-N-K-S"} +{"text": "### FUNCTION Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin ### SEQUENCE -M-I-A-I-E-R-Y-Q-L-I-I-S-K-F-R-M-W-L-F-L-G-C-S-V-E-E-R-H-F-K-Q-P-V-L-I-S-V-T-F-S-Y-N-E-V-P-S-A-C-L-S-D-K-L-S-D-A-C-C-Y-L-E-V-T-S-L-I-E-E-I-A-N-T-K-P-Y-A-L-I-E-H-L-A-N-E-L-F-D-S-L-V-I-S-F-G-D-K-A-S-K-I-D-L-E-V-E-K-E-R-P-P-V-P-N-L-L-N-P-I-K-F-T-I-S-K-E-L-C-P-S-P-V-L-S-A"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-P-K-K-P-N-K-K-N-V-I-Q-R-R-P-S-A-E-K-R-I-L-T-A-Q-K-R-E-L-I-N-H-S-F-K-S-K-V-K-T-I-V-K-K-F-E-A-S-L-K-L-D-D-T-Q-A-T-L-S-N-L-Q-S-V-Y-S-V-V-D-K-A-V-K-R-G-I-F-K-D-N-K-A-A-R-I-K-S-K-A-T-L-K-V-N-A-R-A-S"} +{"text": "### FUNCTION A probable RNA-binding protein ### SEQUENCE -M-K-E-F-L-A-Y-I-I-K-N-L-V-D-R-P-E-E-V-R-I-K-E-V-Q-G-T-H-T-I-I-Y-E-L-S-V-A-K-P-D-I-G-K-I-I-G-K-E-G-R-T-I-K-A-I-R-T-L-L-V-S-V-A-S-R-N-N-V-R-V-S-L-E-I-M-E-E-K"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-V-L-Q-D-T-E-K-K-M-A-A-A-L-D-F-F-H-K-E-V-K-S-F-R-T-G-K-A-H-P-A-L-V-E-T-V-V-V-D-V-Y-G-T-T-M-R-L-S-D-I-A-S-I-S-V-A-D-L-R-Q-L-V-I-S-P-Y-D-G-N-N-A-S-A-I-A-K-G-I-I-A-A-N-L-N-L-Q-P-E-V-E-G-S-I-I-R-I-K-V-P-E-P-T-A-D-Y-R-Q-E-M-I-K-Q-L-R-R-K-C-E-E-A-K-I-N-V-R-N-I-R-R-E-A-N-D-K-L-K-K-D-S-A-L-T-E-D-V-V-K-G-N-E-K-K-I-Q-E-L-T-D-K-F-C-K-Q-L-D-E-L-T-K-Q-K-E-A-E-I-A-S-I"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-V-K-I-I-S-S-E-N-F-D-S-F-I-A-S-G-L-V-L-V-D-F-F-A-E-W-C-G-P-C-R-M-L-T-P-I-L-E-N-L-A-A-E-L-P-H-V-T-I-G-K-I-N-I-D-E-N-S-K-P-A-E-T-Y-E-V-S-S-I-P-T-L-I-L-F-K-D-G-N-E-V-A-R-V-V-G-L-K-D-K-E-F-L-T-N-L-I-N-K-H-A"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-K-D-P-Y-D-V-I-K-R-H-Y-V-T-E-K-A-K-M-L-E-H-L-S-A-G-T-G-E-G-K-K-K-G-S-F-C-K-D-P-K-F-V-F-I-V-S-H-D-A-T-K-P-L-I-A-Q-A-L-E-A-I-Y-V-D-K-N-V-K-V-K-S-V-N-T-I-N-V-K-P-Q-P-A-R-M-F-R-G-R-R-K-G-K-T-S-G-F-K-K-A-I-V-T-F-Y-Q-G-H-S-V-G"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-L-R-K-G-P-F-V-D-H-H-L-L-K-K-V-R-A-M-N-I-E-E-K-K-T-P-I-K-T-W-S-R-R-S-M-I-T-P-E-M-I-G-H-T-F-E-V-H-N-G-K-K-F-L-T-V-F-V-S-E-T-M-V-G-H-K-L-G-E-F-S-P-T-R-I-F-K-S-H-P-V-K-K-G"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-F-K-A-T-A-R-Y-I-R-V-Q-P-R-K-A-R-L-A-A-G-L-M-R-N-L-S-V-Q-E-A-E-E-Q-L-G-F-S-Q-L-K-A-G-R-C-L-K-K-V-L-N-S-A-V-A-N-A-E-L-H-E-N-I-K-R-E-N-L-S-V-T-E-V-R-V-D-A-G-P-V-Y-K-R-S-K-S-K-S-R-G-G-R-S-P-I-L-K-R-T-S-H-L-T-V-I-V-G-E-K-E-R"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-F-R-K-Q-Q-K-G-Q-F-A-G-L-S-K-G-A-T-F-V-D-F-G-E-Y-A-M-Q-T-L-E-R-G-W-V-T-S-R-Q-I-E-A-C-R-V-A-I-N-R-Y-L-K-R-R-G-K-V-W-I-R-I-F-P-D-K-S-V-T-K-K-P-A-E-T-R-M-G-K-G-K-G-A-P-D-H-W-V-A-V-V-R-P-G-R-I-L-F-E-V-A-N-V-S-K-E-D-A-Q-D-A-L-R-R-A-A-A-K-L-G-I-K-T-R-F-V-K-R-V-E-R-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-S-E-P-R-G-S-R-K-V-K-I-G-V-V-V-S-A-K-M-E-K-T-V-V-V-R-V-E-R-I-F-S-H-P-Q-Y-L-K-V-V-R-S-S-K-K-Y-Y-A-H-T-E-L-K-V-S-E-G-D-K-V-K-I-Q-E-T-R-P-L-S-K-L-K-R-W-R-V-I-E-H-V-G-V-V-S"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-Q-L-K-V-A-D-N-T-G-A-K-K-V-K-C-F-K-V-L-G-G-S-R-R-R-Y-A-T-V-G-D-V-I-V-C-S-V-R-D-V-E-P-N-S-S-I-K-K-G-D-V-I-K-A-V-I-V-R-T-R-R-H-I-T-R-K-D-G-S-T-L-K-F-D-T-N-S-C-V-I-I-D-D-K-G-N-P-K-G-T-R-I-F-G-P-V-A-R-E-I-R-D-R-G-F-I-K-I-S-S-L-A-P-E-V-I"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-K-Q-N-I-R-V-G-D-K-V-F-I-L-A-G-N-D-K-G-K-E-G-K-V-L-S-L-T-E-D-K-V-V-V-E-G-V-N-V-R-I-K-N-I-K-R-S-Q-Q-N-P-K-G-K-R-I-S-I-E-A-P-I-H-I-S-N-V-R-L-T-I-A-G-E-P-A-K-L-S-V-K-V-T-E-Q-G-R-E-L-W-Q-R-R-P-D-G-T-S-Q-L-Y-R-L-V-R-G-K-K-G"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-R-L-K-K-F-Y-T-E-E-I-R-K-S-L-F-E-K-F-G-Y-A-N-K-M-Q-I-P-V-L-K-K-I-V-L-S-M-G-L-A-E-A-A-K-D-K-N-L-F-Q-A-H-L-E-E-L-T-M-I-S-G-Q-K-P-L-V-T-K-A-R-N-S-I-A-G-F-K-L-R-E-G-Q-G-I-G-A-K-V-T-L-R-G-I-R-M-Y-D-F-M-D-R-F-C-N-I-V-S-P-R-I-R-D-F-R-G-F-S-N-K-G-D-G-R-G-C-Y-S-V-G-L-D-D-Q-Q-I-F-P-E-I-N-L-D-R-V-K-R-T-Q-G-L-N-I-T-W-V-T-T-A-Q-T-D-D-E-C-T-T-L-L-E-L-M-G-L-R-F-K-K-A-Q"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-M-T-S-D-S-I-A-D-L-L-T-R-I-R-N-A-L-M-A-E-H-L-Y-V-D-V-E-H-S-K-M-R-E-A-I-V-K-I-L-K-H-K-G-F-V-A-H-Y-L-V-K-E-E-N-R-K-R-A-M-R-V-F-L-Q-Y-S-D-D-R-K-P-V-I-H-Q-L-K-R-V-S-K-P-S-R-R-V-Y-V-S-A-A-K-I-P-Y-V-F-G-N-M-G-I-S-V-L-S-T-S-Q-G-V-M-E-G-S-L-A-R-S-K-N-I-G-G-E-L-L-C-L-V-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-K-A-R-E-P-I-L-L-P-Q-G-V-E-V-S-I-Q-D-D-K-I-I-V-K-G-P-K-G-S-L-T-Q-K-S-V-K-E-V-E-I-T-L-K-D-N-S-I-F-V-H-A-A-P-H-V-V-D-R-P-S-C-M-Q-G-L-Y-W-A-L-I-S-N-M-V-Q-G-V-H-L-G-F-E-K-R-L-E-M-I-G-V-G-F-R-A-S-V-Q-G-A-F-L-D-L-S-I-G-V-S-H-P-T-K-I-P-I-P-S-T-L-Q-V-S-V-E-K-N-T-L-I-S-V-K-G-L-D-K-Q-L-V-G-E-F-A-A-S-I-R-A-K-R-P-P-E-P-Y-K-G-K-G-I-R-Y-E-N-E-Y-V-R-R-K-A-G-K-A-A-K-T-G-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-E-S-S-L-C-K-K-S-L-M-K-R-R-R-A-L-R-V-R-K-V-L-K-G-S-P-T-K-P-R-L-S-V-V-K-T-N-K-H-I-Y-V-Q-L-I-D-D-S-I-G-K-T-L-A-S-V-S-T-L-S-K-L-N-K-S-Q-G-L-T-K-K-N-Q-E-V-A-K-V-L-G-T-Q-I-A-E-L-G-K-N-L-Q-L-D-R-V-V-F-D-R-G-P-F-K-Y-H-G-I-V-S-M-V-A-D-G-A-R-E-G-G-L-Q-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-L-S-K-N-S-H-K-E-D-Q-L-E-E-K-V-L-V-V-N-R-C-S-K-V-V-K-G-G-R-K-F-S-F-S-A-L-I-L-V-G-D-G-K-G-R-L-G-Y-G-F-A-K-A-N-E-L-T-D-A-I-R-K-G-G-E-A-A-K-K-N-L-M-K-I-E-A-L-E-D-G-S-I-P-H-E-V-L-V-H-H-D-G-A-Q-L-L-L-K-P-A-K-P-G-T-G-I-V-A-G-S-R-I-R-L-I-L-E-M-A-G-I-K-D-I-V-A-K-S-F-G-S-N-N-P-M-N-Q-V-K-A-A-F-K-A-L-T-G-L-S-P-R-K-D-L-L-R-R-G-A-A-I-N-D"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-I-K-L-E-S-L-F-D-I-S-E-R-K-R-R-K-K-L-L-G-R-G-P-S-S-G-H-G-K-T-S-G-R-G-H-K-G-D-G-S-R-S-G-Y-K-R-R-F-G-Y-E-G-G-G-V-P-L-Y-R-R-V-P-T-R-G-F-S-H-K-R-F-D-K-C-V-E-E-I-T-T-G-R-L-A-E-L-F-Q-E-G-E-A-I-T-L-D-A-L-K-A-K-K-A-I-A-R-Q-A-V-R-V-K-V-I-L-K-G-D-L-E-K-T-F-V-W-Q-D-T-A-V-V-L-S-Q-G-V-Q-N-L-L-G-I-T"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-V-K-N-Q-A-Q-A-K-K-S-V-K-R-K-Q-L-K-N-I-P-S-G-V-V-H-V-K-A-T-F-N-N-T-I-V-S-I-T-D-P-A-G-N-V-I-S-W-A-S-A-G-K-V-G-Y-S-G-S-R-K-S-S-A-F-A-A-T-V-A-A-Q-D-A-A-K-T-A-M-N-S-G-L-K-E-V-E-V-C-L-K-G-T-G-A-G-R-E-S-A-V-R-A-L-I-S-A-G-L-V-V-S-V-I-R-D-E-T-P-V-P-H-N-G-C-R-P-R-K-R-R-R-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-S-A-E-K-R-D-I-P-G-D-P-I-Y-G-S-V-I-L-E-K-F-I-N-K-V-M-M-H-G-K-K-S-V-A-R-K-I-V-Y-S-A-L-E-R-F-G-K-K-L-N-L-E-N-V-L-E-G-F-G-E-A-L-E-N-A-K-P-I-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-A-S-E-R-R-N-C-L-A-M-Q-W-I-I-K-H-A-R-S-K-P-G-K-S-M-E-V-G-L-A-T-E-L-I-D-C-F-N-K-Q-G-A-T-I-K-K-R-E-D-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-K-W"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-Q-Q-K-Q-K-I-R-I-R-L-K-G-F-D-Q-G-Q-L-D-R-S-T-A-D-I-V-E-T-A-K-R-T-G-A-R-V-V-G-P-I-P-L-P-T-K-R-E-V-Y-T-V-L-R-S-P-H-V-D-K-K-S-R-E-Q-F-E-I-R-T-H-K-R-L-V-D-I-L-D-P-T-G-K-T-I-D-A-L-K-M-L-A-L-P-A-G-V-D-I-K-I-K-A-A"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-E-P-Y-A-V-I-Q-T-G-S-K-Q-Y-Q-V-R-S-G-D-V-I-D-V-E-L-L-G-E-V-A-S-D-K-E-V-I-F-Q-D-V-L-F-V-F-D-G-T-K-A-S-L-G-S-P-T-I-A-N-A-Q-V-K-A-E-Y-L-S-H-V-K-G-E-K-V-V-A-Y-K-Y-K-K-R-K-N-Y-H-R-K-H-G-H-R-Q-K-Y-L-R-V-K-I-R-E-I-L-I"} +{"text": "### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Q-C-P-F-C-N-H-G-E-L-K-V-I-D-S-R-N-A-P-E-A-N-A-I-K-R-R-R-E-C-L-K-C-S-Q-R-F-T-T-F-E-T-V-E-L-T-L-Q-V-L-K-R-D-G-R-Y-E-N-F-Q-E-S-K-L-I-H-G-L-N-A-A-S-S-H-T-R-I-G-Q-D-Q-V-H-A-I-A-S-N-V-K-S-E-L-L-G-K-Q-N-R-E-I-S-T-K-E-I-G-E-L-V-M-K-Y-L-K-K-A-D-M-I-A-Y-I-R-F-A-C-V-Y-R-R-F-K-D-V-G-E-L-M-E-V-L-L-S-A-T-P-D-M-E-K"} +{"text": "### FUNCTION Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-uracil ### SEQUENCE -M-F-S-G-I-I-Q-E-L-G-E-V-C-F-F-E-A-Q-G-N-G-L-S-L-G-I-K-S-T-P-L-F-V-T-P-L-V-T-G-D-S-V-A-V-D-G-V-C-L-T-L-T-S-C-N-E-S-K-I-F-F-D-V-I-P-E-T-L-A-C-T-T-L-G-E-K-R-C-S-D-Q-V-N-L-E-A-A-L-K-M-G-D-S-I-G-G-H-L-L-S-G-H-V-F-G-T-A-E-I-F-L-I-K-E-N-R-Y-Y-F-R-G-S-K-E-L-S-Q-Y-L-F-E-K-G-F-I-A-I-D-G-I-S-L-T-L-V-S-V-D-S-D-T-F-S-V-G-L-I-P-E-T-L-Q-R-T-T-L-G-K-K-R-E-G-E-R-V-N-I-E-I-D-M-S-T-K-I-Q-V-D-T-V-K-R-I-L-A-S-S-G-K-D"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-Q-E-K-I-K-I-H-V-S-N-E-Q-T-C-I-P-I-H-L-V-S-V-E-K-L-V-L-T-L-L-E-H-L-K-V-T-T-N-E-I-F-I-Y-F-L-E-D-K-A-L-A-E-L-H-D-K-V-F-A-D-P-S-L-T-D-T-I-T-L-P-I-D-A-P-G-D-P-A-Y-P-H-V-L-G-E-A-F-I-S-P-Q-A-A-L-R-F-L-E-N-T-S-P-N-Q-E-D-I-Y-E-E-I-S-R-Y-L-V-H-S-I-L-H-M-L-G-Y-D-D-T-S-S-E-E-K-R-K-M-R-V-K-E-N-Q-I-L-C-M-L-R-K-K-H-A-L-L-T-A"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-D-T-P-P-E-N-E-E-Q-H-E-S-N-V-Q-N-E-N-E-V-E-H-L-Q-Q-E-I-V-T-L-K-T-E-L-K-E-K-N-D-K-Y-L-M-A-L-A-E-S-E-N-S-R-K-R-L-Q-K-E-R-Q-E-L-M-Q-Y-A-L-E-N-T-L-I-D-F-L-N-P-I-E-S-M-E-K-A-L-G-F-A-T-Q-M-S-D-D-V-K-N-W-A-L-G-F-N-M-I-L-N-Q-F-K-Q-I-F-E-E-K-G-I-I-E-Y-S-S-I-G-Q-K-F-N-P-F-L-H-E-A-V-Q-T-E-E-T-S-E-V-P-E-G-T-I-L-E-E-F-A-K-G-Y-K-I-G-E-R-P-I-R-V-A-K-V-K-V-A-K-A-P-T-P-K-E-N-K-E"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-A-T-M-T-K-K-K-L-I-S-T-I-S-Q-D-H-K-I-H-P-N-H-V-R-T-V-I-Q-N-F-L-D-K-M-T-D-A-L-V-K-G-D-R-L-E-F-R-D-F-G-V-L-Q-V-V-E-R-K-P-K-V-G-R-N-P-K-N-A-A-V-P-I-H-I-P-A-R-R-A-V-K-F-T-P-G-K-R-M-K-R-L-I-E-T-P-N-K-H-S"} +{"text": "### FUNCTION Might have a role in establishing the nucleoid structure of elementary bodies ### SEQUENCE -M-I-G-A-Q-K-K-Q-S-G-K-K-T-A-S-R-A-V-R-K-P-A-K-K-V-A-A-K-R-T-V-K-K-A-T-V-R-K-T-A-V-K-K-P-A-V-R-K-T-A-A-K-K-T-V-A-K-K-T-T-A-K-R-T-V-R-K-T-V-A-K-K-P-A-V-K-K-V-A-A-K-R-V-V-K-K-T-V-A-K-K-T-T-A-K-R-A-V-R-K-T-V-A-K-K-P-V-A-R-K-T-T-V-A-K-G-S-P-K-K-A-A-A-C-A-L-A-C-H-K-N-H-K-H-T-S-S-C-K-R-V-C-S-S-T-A-T-R-K-H-G-S-K-S-R-V-R-T-A-H-G-W-R-H-Q-L-I-K-M-M-S-R"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-Q-K-E-I-V-S-N-R-K-A-L-R-N-Y-E-V-I-E-T-L-E-A-G-I-V-L-T-G-T-E-I-K-S-L-R-D-H-G-G-N-L-G-D-A-Y-V-I-V-S-K-G-E-G-W-L-L-N-A-S-I-A-P-Y-R-F-G-N-I-Y-N-H-E-E-R-R-K-R-K-L-L-L-H-R-Y-E-L-R-K-L-E-G-K-I-A-Q-K-G-M-T-L-I-P-L-G-M-F-L-S-R-G-Y-V-K-V-R-L-G-C-C-R-G-K-K-A-Y-D-K-R-R-T-I-I-E-R-E-K-E-R-E-V-A-A-A-M-K-R-R-H-H"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-T-E-N-R-R-I-K-R-V-N-A-L-L-Q-E-A-I-A-K-V-I-L-K-D-V-K-H-P-K-I-S-N-L-W-I-T-V-T-R-V-S-L-S-K-D-L-H-S-A-R-V-Y-V-S-V-M-P-H-E-N-T-K-E-E-A-L-E-A-L-K-V-S-A-G-F-I-A-H-R-A-S-K-N-V-V-L-K-Y-F-P-E-L-H-F-Y-L-D-D-I-F-S-P-Q-D-Y-I-E-N-L-L-W-Q-I-Q-E-K-E-K-S"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-E-I-I-H-I-G-T-D-I-I-E-I-S-R-I-R-E-A-I-A-T-H-G-N-R-L-L-N-R-I-F-T-E-A-E-Q-K-Y-C-L-E-K-T-D-P-I-P-S-F-A-G-R-F-A-G-K-E-A-V-A-K-A-L-G-T-G-I-G-S-V-V-A-W-K-D-I-E-V-F-K-V-S-H-G-P-E-V-L-L-P-S-H-V-Y-A-K-I-G-I-S-K-V-I-L-S-I-S-H-C-K-E-Y-A-T-A-T-A-I-A-L-A"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-T-R-Y-P-D-Y-L-S-K-L-I-F-F-L-R-K-L-P-G-I-G-F-K-T-A-E-K-L-A-F-E-L-I-S-W-D-S-E-Q-L-K-I-L-G-N-A-F-H-N-V-A-S-E-R-S-H-C-P-L-C-F-T-L-K-E-S-K-E-A-D-C-H-F-C-R-E-E-R-D-N-Q-S-L-C-I-V-A-S-P-K-D-V-F-F-L-E-R-S-K-V-F-K-G-R-Y-H-V-L-G-S-L-L-S-P-I-T-G-K-H-I-E-N-E-R-L-S-I-L-K-S-R-I-E-T-L-C-P-K-E-I-I-L-A-I-D-A-T-L-E-G-D-A-T-A-L-F-L-K-Q-E-L-Q-H-F-S-V-N-I-S-R-L-A-L-G-L-P-I-G-L-S-F-D-Y-V-D-S-G-T-L-A-R-A-F-S-G-R-H-S-Y"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-L-E-D-D-V-I-A-I-I-V-E-Q-L-G-V-D-P-K-E-V-N-E-N-S-S-F-I-E-D-L-N-A-D-S-L-D-L-T-E-L-I-M-T-L-E-E-K-F-A-F-E-I-S-E-E-D-A-E-K-L-R-T-V-G-D-V-F-T-Y-I-K-K-R-Q-A-E-Q"} +{"text": "### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-K-R-Y-V-V-G-I-S-G-A-S-G-V-I-L-A-V-K-L-I-K-E-L-V-N-A-K-H-Q-V-E-V-I-I-S-P-S-G-R-K-T-L-Y-Y-E-L-G-C-Q-S-F-D-A-L-F-S-E-E-N-L-E-Y-I-H-T-H-S-I-Q-A-I-E-S-S-L-A-S-G-S-C-P-V-E-A-T-I-I-I-P-C-S-M-T-T-V-A-A-I-S-I-G-L-A-D-N-L-L-R-R-V-A-D-V-A-L-K-E-R-R-P-L-I-L-V-P-R-E-T-P-L-H-T-I-H-L-E-N-L-L-K-L-S-K-S-G-A-T-I-F-P-P-M-P-M-W-Y-F-K-P-Q-S-V-E-D-L-E-N-A-L-V-G-K-I-L-A-Y-L-N-I-P-S-D-L-T-K-Q-W-S-N-P-E"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-E-K-R-K-D-T-K-T-T-I-V-K-S-S-E-T-T-K-S-W-Y-V-V-D-A-A-G-K-T-L-G-R-L-S-S-E-V-A-K-I-L-R-G-K-H-K-V-T-Y-T-P-H-V-A-M-G-D-G-V-I-V-I-N-A-E-K-V-R-L-T-G-A-K-K-G-Q-K-I-Y-R-Y-Y-T-G-Y-I-S-G-M-R-E-I-P-F-E-N-M-M-A-R-K-P-N-Y-I-I-E-H-A-I-K-G-M-M-P-R-T-R-L-G-K-K-Q-L-K-S-L-R-I-V-K-G-D-S-Y-E-T-F-E-S-Q-K-P-I-L-L-D-I"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-K-P-S-S-C-K-A-Y-L-G-I-D-Y-G-K-K-R-I-G-L-A-Y-A-A-E-P-L-L-L-T-L-P-I-G-N-I-E-A-G-K-N-L-K-L-S-A-E-A-L-H-K-I-I-L-S-R-N-I-T-C-V-V-L-G-N-P-L-P-M-Q-K-G-L-Y-S-S-L-Q-E-E-V-S-L-L-A-E-E-L-K-K-L-S-T-V-E-I-I-L-W-D-E-R-L-S-S-V-Q-A-E-R-M-L-K-Q-D-C-G-L-S-R-K-D-R-K-G-K-T-D-S-L-A-A-T-L-I-L-T-S-F-L-D-S-L-P-K-K-L-T-L"} +{"text": "### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-I-N-F-I-R-S-Y-A-L-Y-F-A-W-A-I-S-C-A-G-T-L-I-S-I-F-Y-S-Y-I-L-N-V-E-P-C-I-L-C-Y-Y-Q-R-I-C-L-F-P-L-T-V-I-L-G-I-S-A-Y-R-E-D-S-S-I-K-L-Y-I-L-P-Q-A-V-L-G-L-G-I-S-I-Y-Q-V-F-L-Q-E-I-P-G-M-Q-L-D-I-C-G-R-V-S-C-S-T-K-I-F-L-F-S-Y-V-T-I-P-M-A-S-V-V-A-F-G-A-I-V-C-L-L-V-L-T-K-K-Y-R-G"} +{"text": "### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-K-K-V-T-I-D-E-A-L-K-E-I-L-R-L-E-G-A-A-T-Q-E-E-L-C-A-K-L-L-A-Q-G-F-A-T-T-Q-S-S-V-S-R-W-L-R-K-I-Q-A-V-K-V-A-G-E-R-G-A-R-Y-S-L-P-S-S-T-E-K-T-T-T-R-H-L-V-L-S-I-R-H-N-A-S-L-I-V-I-R-T-V-P-G-S-A-S-W-I-A-A-L-L-D-Q-G-L-K-D-E-I-L-G-T-L-A-G-D-D-T-I-F-V-T-P-I-D-E-G-R-L-P-L-L-M-V-S-I-A-N-L-L-Q-V-F-L-D"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-L-S-S-Q-L-S-V-G-M-F-I-S-T-K-D-G-L-Y-K-V-T-S-V-S-K-V-A-G-P-K-G-E-S-F-I-K-V-A-L-Q-A-A-D-S-D-V-V-I-E-R-N-F-K-A-T-Q-E-V-K-E-A-Q-F-E-T-R-T-L-E-Y-L-Y-L-E-D-E-S-Y-L-F-L-D-L-G-N-Y-E-K-L-F-I-P-Q-E-I-M-K-D-N-F-L-F-L-K-A-G-V-T-V-S-A-M-V-Y-D-N-V-V-F-S-V-E-L-P-H-F-L-E-L-M-V-S-K-T-D-F-P-G-D-S-L-S-L-S-G-G-V-K-K-A-L-L-E-T-G-I-E-V-M-V-P-P-F-V-E-I-G-D-V-I-K-I-D-T-R-T-C-E-Y-I-Q-R-V"} +{"text": "### FUNCTION This protein is a component of the acetyl coenzyme A carboxylase complex ### SEQUENCE -M-D-L-K-Q-I-E-K-L-M-I-A-M-G-R-N-G-M-K-R-F-A-I-K-R-E-G-L-E-L-E-L-E-R-D-T-R-E-G-N-R-Q-E-P-V-F-Y-D-S-R-L-F-S-G-F-S-Q-E-R-P-I-P-T-D-P-K-K-D-T-I-K-E-T-T-T-E-N-S-E-T-S-T-T-T-S-S-G-D-F-I-S-S-P-L-V-G-T-F-Y-G-S-P-A-P-D-S-P-S-F-V-K-P-G-D-I-V-S-E-D-T-I-V-C-I-V-E-A-M-K-V-M-N-E-V-K-A-G-M-S-G-R-V-L-E-V-L-I-T-N-G-D-P-V-Q-F-G-S-K-L-F-R-I-A-K-D-A-S"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-V-N-L-L-K-E-L-E-Q-E-Q-C-R-N-D-L-P-E-F-H-V-G-D-T-I-R-L-A-T-K-I-S-E-G-G-K-E-R-V-Q-V-F-Q-G-T-V-M-A-R-R-G-G-G-S-G-E-T-V-S-L-H-R-V-A-Y-G-E-G-M-E-K-S-F-L-L-N-S-P-R-I-V-S-I-E-I-V-K-R-G-K-V-A-R-A-R-L-Y-Y-L-R-G-K-T-G-K-A-A-K-V-K-E-F-V-G-P-R-S-S-K-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-T-T-E-S-L-E-T-L-V-E-K-L-S-N-L-T-V-L-E-L-S-Q-L-K-K-L-L-E-E-K-W-D-V-T-A-S-A-P-V-V-A-V-A-A-G-G-G-G-E-A-P-V-A-A-E-P-T-E-F-A-V-T-L-E-D-V-P-A-D-K-K-I-G-V-L-K-V-V-R-E-V-T-G-L-A-L-K-E-A-K-E-M-T-E-G-L-P-K-T-V-K-E-K-T-S-K-S-D-A-E-D-T-V-K-K-L-Q-D-A-G-A-K-A-S-F-K-G-L"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-K-Q-E-K-T-L-L-L-Q-E-V-E-D-K-I-S-A-A-Q-G-F-I-L-L-R-Y-L-R-F-T-A-A-Y-S-R-E-F-R-N-S-L-S-G-V-S-A-E-F-E-V-L-K-K-R-I-F-F-K-A-I-E-A-A-G-L-E-V-D-C-S-D-T-D-G-H-L-G-V-V-F-S-C-G-D-P-V-S-A-A-K-Q-V-L-D-F-N-K-Q-H-K-D-S-L-V-F-L-A-G-R-M-D-N-A-S-L-S-G-A-E-V-E-A-V-A-K-L-P-S-L-K-E-L-R-Q-Q-V-V-G-L-F-A-A-P-M-S-Q-V-V-G-I-M-N-S-V-L-S-G-V-I-S-C-V-D-Q-K-A-G-K-N"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-S-V-K-K-V-I-K-I-I-K-L-Q-I-P-G-G-K-A-N-P-A-P-P-I-G-P-A-L-G-A-A-G-V-N-I-M-G-F-C-K-E-F-N-A-A-T-Q-D-K-P-G-D-L-L-P-V-V-I-T-V-Y-A-D-K-T-F-T-F-I-T-K-Q-P-P-V-S-S-L-I-K-K-T-L-N-L-E-S-G-S-K-I-P-N-R-N-K-V-G-K-L-T-Q-A-Q-V-E-A-I-A-E-Q-K-M-K-D-M-D-I-V-L-L-E-S-A-K-R-M-V-E-G-T-A-R-S-M-G-I-D-V-E"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-Y-K-W-Y-V-V-Q-V-F-T-A-Q-E-K-K-V-K-K-A-L-E-D-F-K-E-S-S-G-M-T-D-F-I-Q-E-I-I-L-P-I-E-N-V-M-E-V-K-K-G-E-H-K-V-V-E-K-Y-I-W-P-G-Y-L-L-V-K-M-H-L-T-D-E-S-W-L-Y-V-K-S-T-A-G-I-V-E-F-L-G-G-G-V-P-V-A-L-S-E-D-E-V-R-S-I-L-T-D-I-E-E-K-K-S-G-V-V-Q-K-H-Q-F-E-V-G-S-R-V-K-I-N-D-G-V-F-V-N-F-I-G-T-V-S-E-V-F-H-D-K-G-R-L-S-V-M-V-S-I-F-G-R-E-T-R-V-D-D-L-E-F-W-Q-V-E-E-V-A-P-G-Q-E-S-E"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-K-E-D-T-L-V-L-E-G-K-V-E-E-L-L-P-G-M-H-F-R-V-I-L-E-N-G-M-P-V-T-A-H-L-C-G-K-M-R-M-S-N-I-R-L-L-V-G-D-R-V-T-V-E-M-S-A-Y-D-L-T-K-A-R-V-V-Y-R-H-R"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-V-F-C-E-L-D-S-G-G-E-L-P-E-Y-T-T-P-G-A-A-G-A-D-L-R-A-N-I-E-E-P-I-A-L-L-P-G-Q-R-A-L-I-P-T-G-I-K-A-E-I-P-E-G-Y-E-L-Q-V-R-P-R-S-G-L-A-L-K-H-G-I-T-V-L-N-S-P-G-T-I-D-S-D-Y-R-G-E-I-R-V-I-L-I-N-F-G-D-S-T-F-I-I-E-P-K-M-R-I-A-Q-V-V-L-S-P-V-V-Q-A-T-F-V-V-K-Q-E-S-L-A-E-T-A-R-G-S-G-G-F-G-H-T-G-A-S"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-G-S-G-Y-A-K-K-K-K-E-A-K-I-M-E-Q-Q-F-L-E-M-E-A-S-L-L-E-K-R-Y-E-G-Q-A-G-N-G-L-V-S-V-V-I-N-G-K-C-D-L-I-S-V-K-V-Q-P-T-C-L-D-P-E-D-P-E-V-I-E-D-L-F-R-A-A-F-K-L-A-K-E-Q-M-D-Q-E-M-S-L-M-R-S-T-M-P-F"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-N-E-P-T-R-T-Y-L-E-S-E-K-D-T-Q-D-Q-I-E-E-L-Q-A-T-C-I-V-K-N-A-A-G-I-H-V-R-P-A-G-V-I-V-R-L-F-D-G-E-P-C-D-V-H-F-T-Y-A-G-K-T-I-N-A-K-S-I-M-S-I-L-M-L-G-A-P-Q-G-G-E-I-L-V-T-I-R-S-K-E-A-H-R-I-L-Q-K-I-Q-D-A-F-S-S-G-F-G-E-L"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-S-L-P-L-V-L-G-S-S-S-P-R-R-K-F-I-L-E-K-F-R-V-P-F-T-V-I-P-S-N-F-D-E-S-K-V-S-Y-S-G-D-P-I-A-Y-T-Q-E-L-A-A-Q-K-A-Y-A-V-S-E-L-H-S-P-C-D-C-I-I-L-T-G-D-T-I-V-S-Y-D-G-R-I-F-T-K-P-Q-D-K-A-D-A-I-Q-M-L-K-T-L-R-N-Q-T-H-D-V-V-T-S-I-A-V-L-H-K-G-K-L-L-T-G-S-E-T-S-Q-I-S-L-T-M-I-P-D-H-R-I-E-S-Y-I-D-T-V-G-T-L-N-N-C-G-A-Y-D-V-C-H-G-G-L-I-L-K-K-V-H-G-C-V-Y-N-V-Q-G-L-P-I-Q-T-L-K-Y-L-L-E-E-L-N-I-D-L-W-D-Y-S-I"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-E-Q-F-H-L-D-R-E-E-I-L-L-L-A-K-A-S-A-L-Q-L-S-E-E-L-I-Q-E-Y-Q-T-S-L-S-A-V-I-T-S-M-K-E-A-L-A-I-E-I-D-D-A-D-S-C-E-S-L-F-M-H-V-V-N-V-E-D-L-R-E-D-S-V-T-S-D-F-N-R-E-E-F-L-R-N-V-P-E-S-L-G-G-L-V-K-V-P-A-V-I-K"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-R-R-I-D-P-N-T-L-E-L-E-E-K-V-V-A-I-N-R-V-A-K-V-V-K-G-G-R-R-F-R-F-A-A-L-V-V-V-G-D-K-N-G-R-V-G-F-G-M-G-K-A-Q-E-V-P-E-A-I-R-K-A-V-E-D-A-K-K-N-L-I-E-V-P-I-V-G-T-T-I-P-H-E-I-V-G-R-F-G-A-G-R-V-L-L-K-P-A-S-E-G-T-G-V-I-A-G-G-P-V-R-A-V-L-D-L-A-G-V-G-D-I-L-S-K-S-L-G-S-N-N-P-I-N-M-V-R-A-T-V-K-G-L-Q-E-L-K-R-A-E-D-V-A-K-L-R-G-K-T-V-E-E-L-L-G"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-T-K-P-I-K-N-V-A-R-K-K-R-H-A-H-V-R-R-T-I-T-G-T-P-E-R-P-R-L-N-V-F-R-S-S-K-H-I-Y-A-Q-L-I-D-D-V-N-G-V-T-V-A-A-A-S-S-L-D-K-E-L-K-L-E-N-G-G-N-V-E-A-A-K-K-V-G-E-L-V-A-K-R-A-L-E-K-G-Y-K-T-I-V-F-D-R-G-G-Y-V-Y-H-G-R-V-A-S-L-A-D-A-A-R-E-A-G-L-Q-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-P-V-E-I-P-S-G-V-T-V-T-V-N-G-A-D-V-T-V-K-G-P-K-G-E-L-K-R-T-F-N-P-E-I-V-V-K-V-E-D-N-T-V-V-V-E-R-P-S-D-K-K-E-H-R-A-L-H-G-T-T-R-S-L-I-S-N-M-V-E-G-V-S-K-G-F-E-K-S-L-E-L-V-G-V-G-Y-R-A-Q-K-S-G-Q-K-L-V-L-N-V-G-Y-S-H-P-V-E-I-V-P-E-K-G-I-E-I-E-V-P-S-N-T-K-V-T-V-K-G-I-D-K-E-R-V-G-A-V-A-S-N-I-R-S-V-R-L-P-E-P-Y-K-G-K-G-I-R-Y-E-G-E-Y-V-R-R-K-E-G-K-T-G-K"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-S-D-M-L-T-R-I-R-N-A-N-T-V-R-H-E-K-L-E-L-P-A-S-K-I-K-K-E-I-A-E-I-L-K-R-E-G-F-I-R-D-Y-E-Y-I-E-D-S-K-Q-G-V-I-R-I-F-L-K-Y-G-S-S-N-E-R-V-I-T-G-L-K-R-I-S-K-P-G-L-R-V-Y-A-K-A-G-E-L-P-R-V-L-G-G-L-G-I-A-I-V-S-T-S-K-G-V-M-T-D-K-E-A-R-Q-Q-Q-V-G-G-E-V-L-A-Y-V-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-Q-K-R-T-Q-K-Y-K-V-R-E-Y-T-R-C-E-R-C-G-R-P-H-S-V-M-R-K-F-K-L-C-R-I-C-F-R-E-L-A-Y-K-G-Q-I-P-G-V-K-K-A-S-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-E-K-Y-Q-K-E-I-V-P-S-L-T-E-K-F-N-Y-S-S-V-M-A-V-P-K-L-E-K-I-V-V-N-M-G-V-G-D-A-V-Q-N-A-K-A-L-D-K-A-V-E-E-L-T-E-I-T-G-Q-K-P-I-I-T-K-A-K-K-S-I-A-G-F-K-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-I-S-V-S-L-P-R-V-R-D-F-R-G-I-S-K-K-A-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-D-Y-D-K-V-D-K-V-R-G-M-D-V-V-I-V-T-T-A-S-T-D-E-E-A-R-E-L-L-S-Q-M-G-M-P-F-Q-K"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-H-V-K-K-G-D-T-V-K-V-I-S-G-K-D-K-G-K-Q-G-V-I-L-E-A-Y-P-K-K-D-R-V-L-V-E-G-V-N-I-V-K-K-H-A-K-P-S-Q-E-N-P-Q-G-G-I-L-N-M-E-A-P-I-H-V-S-N-V-L-P-I-D-P-K-T-G-E-P-T-R-V-G-Y-K-V-E-N-G-K-K-V-R-I-A-K-K-S-G-E-V-L-D-K"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-S-G-A-R-E-L-L-C-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-V-I-V-C-S-V-K-Q-A-T-P-G-G-V-V-K-K-G-D-V-V-K-A-V-I-V-R-S-K-S-G-V-R-R-N-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-V-R-D-D-K-S-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-N-Q-F-M-K-I-V-S-L-A-P-E-V-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-N-Q-R-K-V-Y-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-L-V-E-T-Y-K-K-D-R-L-Y-G-K-R-V-K-Y-S-K-K-F-K-A-H-D-E-N-N-S-A-K-I-G-D-I-V-R-I-Q-E-T-R-P-L-S-K-D-K-H-F-R-L-V-E-I-V-E-E-A-V-I-I"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-F-R-R-E-H-R-G-K-M-R-G-R-A-K-G-G-T-E-V-H-F-G-E-Y-G-L-Q-A-L-E-A-S-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-S-K-P-Y-T-A-K-P-L-E-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-V-V-K-P-G-K-V-M-F-E-I-S-G-V-S-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-C-K-F-V-K-R-E-E-V-G-G-D-A-N-E-N"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-Q-A-K-A-V-A-K-Q-V-R-I-A-P-R-K-A-R-L-V-I-D-L-I-R-G-K-Q-V-G-E-A-I-A-I-L-K-H-T-P-K-A-A-S-P-I-I-E-K-V-L-N-S-A-I-A-N-A-E-H-N-Y-E-M-E-P-N-N-L-V-I-S-E-A-F-V-D-E-G-V-T-L-K-R-F-R-P-R-A-M-G-R-A-S-R-I-N-K-R-T-S-H-I-T-I-V-V-T-E-K-K-E-G"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-V-D-D-H-L-M-K-K-I-E-T-L-N-E-S-N-D-K-K-V-V-K-T-W-S-R-R-S-T-I-F-P-E-F-V-G-H-T-I-A-V-Y-D-G-R-K-H-V-P-V-Y-I-S-E-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-K-G-H-A-A-D-D-K-K-T-R-R"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-N-A-R-D-V-I-K-R-P-V-I-T-E-R-S-T-E-V-M-G-D-K-K-Y-T-F-E-V-D-V-R-A-N-K-T-Q-I-K-D-A-I-E-E-I-F-D-V-K-V-A-K-V-N-T-M-N-Y-K-G-K-P-K-R-F-G-R-Y-T-G-F-T-A-R-R-K-K-A-I-V-T-L-T-P-D-S-K-E-L-D-F-F-E-G-V"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-K-Q-K-I-R-I-R-L-K-A-Y-D-H-R-V-L-D-Q-S-A-E-K-I-V-E-T-A-K-R-S-G-A-N-V-S-G-P-I-P-L-P-T-E-K-S-V-Y-T-I-L-R-A-V-H-K-Y-K-D-S-R-E-Q-F-E-M-R-T-H-K-R-L-I-D-I-V-N-P-T-P-Q-T-V-D-A-L-M-R-L-D-L-P-S-G-V-D-I-E-I-K-L"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-A-R-R-D-V-L-P-D-P-I-Y-N-S-K-L-V-T-R-L-I-N-R-I-M-V-D-G-K-R-G-I-A-Q-K-I-L-Y-N-A-F-E-L-V-R-E-R-S-G-K-D-P-M-E-V-F-D-Q-A-L-K-N-I-M-P-V-L-E-V-K-A-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-K-P-E-R-R-T-T-L-G-L-R-W-L-V-N-Y-S-R-L-R-G-E-K-T-M-E-E-R-L-A-N-E-I-L-D-A-A-N-N-T-G-A-A-V-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W"} +{"text": "### FUNCTION Strong inhibitor of bacterial serine proteases such as subtilisin ### SEQUENCE -M-R-N-R-A-K-T-A-L-V-G-T-L-V-A-A-T-A-A-L-G-P-L-G-G-T-A-H-A-G-D-S-S-L-Y-A-P-S-D-L-V-L-T-I-A-H-G-E-D-A-A-S-V-A-P-E-R-A-V-T-L-T-C-E-P-Q-A-R-G-T-H-P-S-P-Q-E-A-C-V-L-L-G-D-A-G-G-D-V-D-A-I-A-P-P-A-E-P-Q-L-C-T-Y-Q-Y-D-P-V-V-V-T-C-X-G-V-W-Q-G-R-F-V-D-Q-E-R-T-F-G-N-E-C-V-M-R-A-E-T-G-A-V-F-D-F"} +{"text": "### FUNCTION Component of the phosphoenolpyruvate-dependent nitrogen-metabolic phosphotransferase system proteins ### SEQUENCE -M-T-Q-Y-R-R-V-A-I-K-N-R-L-G-M-H-A-R-P-A-M-K-L-F-D-L-V-N-T-F-Q-S-T-V-T-L-R-N-H-E-G-V-E-A-Q-A-D-S-V-I-A-M-L-M-L-D-S-E-Q-G-S-H-I-D-I-E-A-S-G-C-D-E-K-E-A-I-D-A-I-I-A-L-F-E-S-G-F-D-E-D"} +{"text": "### FUNCTION Required for coenzyme pyrroloquinoline quinone ### SEQUENCE -M-W-T-K-P-S-F-T-D-L-R-L-G-F-E-V-T-L-Y-F-A-N-R"} +{"text": "### FUNCTION General is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-A-S-K-E-F-H-I-V-A-E-T-G-I-H-A-R-P-A-T-L-L-V-Q-T-A-S-K-F-T-S-E-I-T-L-E-Y-K-G-K-S-V-N-L-K-S-I-M-G-V-M-S-L-G-V-G-Q-G-A-D-V-T-I-S-A-E-G-A-D-A-D-D-A-I-A-T-I-A-E-T-M-T-K-E-G-L-A-E"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-K-K-E-S-K-K-E-Q-R-L-R-R-H-R-R-V-R-K-K-V-F-G-T-P-E-R-P-R-L-C-V-F-R-S-N-K-H-I-Y-A-Q-I-I-D-D-T-I-G-H-T-L-V-S-A-S-T-L-D-P-E-L-R-E-K-L-Q-K-T-W-N-V-E-A-A-K-E-V-G-L-L-I-G-K-R-A-L-E-K-G-I-K-K-V-V-F-D-R-G-G-Y-K-Y-H-G-R-V-K-A-L-A-D-G-A-R-E-A-G-L-E-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-L-A-K-K-P-I-V-L-P-Q-G-V-T-V-E-I-K-D-N-V-V-K-V-K-G-P-K-G-E-L-S-Q-E-F-L-P-Y-V-K-I-E-V-E-G-N-E-V-W-V-R-P-N-E-E-Q-I-I-R-K-S-D-W-R-K-V-K-M-F-Q-G-T-Y-W-S-L-I-R-N-M-V-V-G-V-T-E-G-Y-K-K-E-L-E-I-V-G-I-G-Y-R-A-Q-L-Q-G-N-T-L-V-M-N-L-G-Y-A-H-P-V-V-Y-E-I-P-S-D-V-K-I-E-V-P-A-P-N-R-I-I-V-S-G-I-D-K-Q-R-V-G-Q-V-A-A-E-I-R-A-F-R-P-P-N-V-Y-T-G-K-G-I-R-Y-V-G-E-V-V-R-Q-K-E-G-K-K-A"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-W-S-D-P-I-A-D-M-L-T-R-I-R-N-A-N-M-V-F-K-E-Y-T-D-I-P-A-S-N-L-K-K-K-I-C-E-I-L-K-R-E-G-F-I-A-D-Y-K-Y-I-E-D-G-K-Q-G-I-L-R-V-Y-L-K-Y-K-G-G-R-K-N-R-E-R-V-I-H-G-I-V-R-V-S-H-A-G-R-R-I-Y-V-D-K-D-H-I-P-K-V-K-N-G-L-G-I-A-I-L-T-T-S-K-G-V-L-T-D-K-E-A-R-Q-L-G-V-G-G-E-V-I-A-Y-V-W"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-A-M-I-E-R-W-K-K-P-K-K-Y-K-V-R-E-Y-T-R-C-H-I-C-G-R-P-R-A-V-Y-R-E-F-G-L-C-R-I-C-F-R-K-L-A-L-E-G-K-L-P-G-V-R-K-A-S-W"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-K-H-Y-E-V-L-F-I-L-K-P-T-L-T-E-E-E-V-N-T-K-L-E-F-V-K-E-V-L-T-K-N-S-A-E-I-E-T-V-V-P-M-G-T-R-K-L-A-Y-K-I-K-K-Y-E-R-G-T-Y-F-V-I-Y-F-K-A-P-T-N-L-I-A-E-L-E-R-V-L-R-I-T-E-E-V-I-R-F-L-I-V-K-Y-E-N-K-K-E-I-A-A-W-E-K-L-S-H-G-I-K-Q-S-K-K-E-I-K-P-L-D-A-P-E-I-Q"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-H-G-I-G-V-D-L-I-E-I-D-R-I-Q-A-L-Y-S-K-Q-P-K-L-V-E-R-I-L-T-K-N-E-Q-H-K-F-N-N-F-T-H-E-Q-R-K-I-E-F-L-A-G-R-F-A-T-K-E-A-F-S-K-A-L-G-T-G-L-G-K-H-V-A-F-N-D-I-D-C-Y-N-D-E-L-G-K-P-K-I-D-Y-E-G-F-I-V-H-V-S-I-S-H-T-E-H-Y-A-M-S-Q-V-V-L-E-K-S-A-F"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-F-K-D-W-M-N-N-L-R-D-Y-F-V-E-D-D-E-E-F-N-E-P-T-R-P-V-Q-E-S-R-P-T-V-A-S-T-P-K-P-K-V-E-E-R-K-V-Q-A-D-Y-Q-S-R-R-P-A-Q-T-T-P-K-P-Q-T-Q-T-A-A-P-K-R-S-A-S-T-F-S-K-P-M-P-E-K-I-V-Q-Q-Q-T-V-S-Q-A-Q-S-L-A-A-T-V-S-T-I-A-I-K-E-P-R-A-Y-A-D-I-M-E-S-A-R-I-V-K-N-G-E-C-V-L-V-N-F-K-F-M-G-D-A-Q-A-R-R-S-I-D-F-M-T-G-V-V-F-T-L-D-G-D-I-Q-N-V-G-G-Q-I-F-L-M-T-P-A-N-I-T-V-D-A-A-K-E-M-S-I-L-A-G-Q-N-F-E-S-Y-D-I-Y"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-V-N-K-V-I-I-I-G-N-L-G-R-D-P-E-V-R-S-F-Q-N-G-G-K-V-V-N-L-R-I-A-T-S-E-Q-W-R-D-R-A-S-G-E-R-K-E-R-T-E-W-H-S-V-A-I-F-D-E-N-L-A-R-V-A-E-Q-Y-L-R-K-G-S-T-V-Y-I-E-G-Q-L-E-T-R-K-W-Q-D-Q-S-G-Q-D-R-Y-S-T-E-V-V-L-R-P-F-R-S-S-L-T-M-L-G-G-R-G-E-G-A-G-A-G-G-G-M-G-G-G-G-Y-E-D-R-G-G-P-D-N-Y-D-N-Y-G-S-G-P-R-G-G-A-S-S-G-G-A-P-S-G-G-G-R-R-N-D-L-D-D-E-I-P-F"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-K-Y-I-L-A-I-D-F-G-L-K-K-I-G-T-A-I-A-N-T-L-D-K-Y-P-S-A-F-H-V-F-E-V-K-N-N-F-K-T-A-V-N-N-L-F-L-R-I-K-N-D-G-Y-E-L-E-K-I-V-I-G-F-P-K-F-H-Y-Y-S-D-I-Q-K-A-I-K-S-F-K-Q-L-L-E-K-R-F-N-L-P-I-I-L-V-D-E-S-N-T-T-S-A-V-K-D-K-L-I-T-M-D-L-K-H-K-D-F-K-K-A-K-D-T-L-A-A-V-L-I-L-E-R-F-F-Q-N-Y-H"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-V-V-G-I-G-I-D-V-V-Q-L-K-R-F-L-T-L-V-E-T-S-D-C-F-A-K-R-L-L-T-S-N-E-L-N-S-Y-W-K-L-N-N-N-Q-R-A-N-F-L-A-V-H-W-T-L-K-E-A-I-Y-K-A-T-S-H-I-K-P-L-F-T-K-L-E-I-Y-K-L-N-N-Q-Y-R-C-E-F-I-Q-N-I-N-L-L-L-S-V-S-Y-T-N-C-H-V-S-A-I-C-L-A-Q-Q-N-G"} +{"text": "### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate ### SEQUENCE -M-Q-Q-E-R-T-V-K-V-S-K-Y-L-S-K-H-L-R-H-Q-P-E-R-I-G-L-T-P-D-E-G-G-W-V-E-I-D-A-L-V-A-A-A-A-A-H-G-F-P-F-T-R-Q-E-L-D-H-V-V-A-T-N-D-K-R-R-F-A-V-E-G-T-R-I-R-A-S-Q-G-H-S-I-A-V-D-L-R-L-P-V-A-T-P-P-P-Y-L-Y-H-G-T-V-A-R-H-L-E-A-I-R-A-E-G-L-R-P-M-N-R-H-D-V-H-L-S-P-D-R-E-T-A-T-R-V-G-A-R-R-G-R-P-V-V-L-P-V-D-A-A-T-M-H-R-D-G-H-V-F-H-V-S-A-N-G-V-W-L-T-Q-H-V-P-S-R-Y-L-R-F-P-A-P-H"} +{"text": "### FUNCTION Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms They allow the positioning of the organism at the favorable depth for growth This protein could be important for the shape determination of the gas vesicle ### SEQUENCE -M-T-T-P-S-R-L-P-D-P-Y-G-Q-G-Q-S-A-N-L-A-D-I-L-E-R-V-L-D-K-G-V-V-I-A-G-D-I-K-I-N-L-L-D-I-E-L-L-T-I-K-L-R-L-V-V-A-S-V-D-K-A-K-E-M-G-I-D-W-W-E-S-D-P-A-L-S-S-R-A-R-H-D-E-L-T-R-E-N-A-A-L-R-E-R-L-R-E-L-D-P-G-R-V-P-R-E-E-A-P"} +{"text": "### FUNCTION Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition GvpA forms the protein shell ### SEQUENCE -M-T-V-V-P-A-Q-Q-T-G-G-G-G-S-S-G-L-Y-D-V-L-E-L-V-L-D-R-G-L-V-I-D-A-F-V-R-V-S-L-V-G-I-E-I-L-K-I-D-V-R-V-V-V-A-S-V-D-T-Y-L-R-F-A-E-A-C-N-R-L-D-L-E-A-G-P-R-K-D-P-G-L-P-D-L-V-G-E-M-T-E-S-G-A-R-G-K-S-K-G-A-L-S-G-A-A-E-T-I-S-D-A-F-K-Q-A-R-D-D-G-G-S-E-R-E-T-S-S-R-P-R-A-R-K-A-A-P-S-R-R-K-E-E-Q-E"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-V-N-F-N-Q-F-L-K-Q-A-Q-S-M-Q-K-K-M-Q-E-A-Q-E-Q-M-A-N-T-R-Y-T-G-K-A-G-G-M-L-V-E-I-I-I-T-G-K-G-E-V-E-K-I-S-I-D-E-S-L-L-K-T-E-E-K-E-M-L-E-D-L-I-K-V-A-F-N-D-A-K-Q-K-C-D-E-D-S-Q-N-S-L-S-G-A-L-N-G-M-S-L-P-P-G-F-K-I-P-F"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-L-N-K-V-I-L-I-G-N-V-G-R-D-P-E-I-R-T-T-G-E-G-K-K-I-I-N-L-S-L-A-T-T-E-T-W-K-D-R-I-T-S-E-R-K-E-R-T-E-W-H-R-V-V-I-F-S-E-G-L-V-S-I-V-E-R-Y-V-T-K-G-S-K-L-Y-I-E-G-S-L-Q-T-R-K-W-N-D-N-S-G-Q-E-K-Y-T-T-E-V-V-L-Q-N-F-N-S-Q-L-I-L-L-D-H-K-N-S-N-Q-N-T-Q-G-S-G-H-H-E-Y-K-Y-P-E-T-K-N-H-S-F-D-H-S-D-L-D-D-E-I-P-F"} +{"text": "### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-T-Y-V-V-T-D-E-C-V-K-C-K-Y-T-D-C-V-E-V-C-P-V-D-C-F-Y-E-G-E-F-M-L-V-I-N-P-D-E-C-I-D-C-G-V-C-V-P-D-C-P-I-D-A-I-K-P-E-S-P-E-L-I-E-W-V-E-R-A-K-D-F-I-E-N-H-G-W-K-N-I-T-K-K-K-C-A-L-P-G-A-D-K-F-K-D-E-K-D-K-F-N-K-Y-I-I-K-K-T"} +{"text": "### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-L-I-Q-F-T-G-T-V-L-E-L-L-P-N-A-T-F-R-V-K-L-E-N-D-H-I-I-I-A-H-T-S-G-R-M-R-K-N-R-I-R-I-L-L-G-D-K-V-T-V-E-M-T-P-Y-D-L-T-K-G-R-V-I-H-R-H"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-K-D-N-L-I-Q-N-Y-A-V-A-L-F-N-N-A-L-L-D-N-I-Q-V-K-I-C-E-E-I-T-L-L-N-S-I-I-E-D-S-F-E-I-K-K-F-L-F-S-P-L-V-N-K-I-D-K-I-N-V-F-N-S-L-V-K-T-T-N-F-N-K-I-V-N-N-F-L-L-L-L-I-K-N-S-R-T-H-I-L-S-N-I-V-E-V-Y-N-K-L-L-Y-E-S-R-N-I-K-I-V-H-V-I-S-T-N-E-L-Q-P-K-E-Q-E-W-I-Q-S-R-I-E-K-E-L-Q-H-K-T-E-L-F-F-D-I-D-N-T-I-I-G-G-I-V-I-K-Y-D-N-V-L-R-D-Y-S-I-K-G-S-L-E-K-I-A-K-C-L-K-N-V-K-I-C"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-H-E-T-I-R-V-K-I-I-T-P-S-S-I-A-F-E-K-Q-S-K-M-V-T-M-P-G-E-D-G-M-F-G-V-L-P-H-H-V-P-M-I-V-N-L-K-A-G-L-V-Q-I-Y-I-Y-N-I-H-N-Y-E-N-T-Y-L-I-S-G-G-V-T-E-I-T-S-H-Y-I-N-I-V-T-E-V-A-I-N-V-T-N-L-S-E-S-E-I-S-T-Q-R-Y-E-L-Q-K-L-L-S-H-Q-H"} +{"text": "### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-K-F-K-N-K-G-L-I-I-I-L-S-S-P-S-G-T-G-K-S-S-L-A-K-E-L-L-K-I-D-N-N-L-R-L-S-I-S-V-T-T-R-K-P-R-L-G-E-V-D-G-I-N-Y-Y-F-K-S-D-R-E-F-K-T-L-V-K-Q-N-K-F-L-E-Y-A-K-I-Y-N-D-Y-Y-G-T-P-K-E-Y-V-K-M-L-L-K-Q-G-F-D-V-L-F-D-I-D-W-Q-G-V-R-S-I-K-K-N-T-N-N-V-I-T-I-F-I-L-P-P-S-I-E-I-L-E-Q-R-L-R-N-R-A-T-D-N-E-E-T-I-K-L-R-M-Q-S-A-Q-N-E-I-S-H-A-N-E-Y-D-Y-V-V-I-N-D-D-F-S-Q-T-L-K-K-I-H-E-I-I-V-A-E-R-A-K-N-F-A-Y-H-E-Y"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-E-F-K-I-M-S-T-T-D-K-I-E-Q-K-V-I-E-M-V-A-E-K-L-N-K-D-K-A-I-I-T-T-D-S-R-F-I-E-D-L-K-A-D-S-L-D-T-V-E-L-M-M-A-I-E-V-E-Y-G-I-D-I-P-D-D-E-A-T-K-I-K-T-V-S-D-V-I-K-Y-I-K-E-R-Q-S"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-I-K-A-G-G-K-Q-Y-K-V-D-R-N-S-V-I-K-V-E-K-I-D-G-E-L-G-S-K-I-Q-F-D-Q-I-L-M-I-G-E-Y-S-K-P-S-F-I-G-T-P-I-V-K-G-A-I-V-T-A-E-I-T-N-Q-L-K-D-N-K-I-I-A-F-K-K-K-R-R-K-N-Y-R-R-K-A-G-H-R-Q-E-L-T-E-L-K-I-L-D-I-T-K-Q"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-M-S-F-S-H-L-L-I-V-L-L-I-I-F-V-L-F-G-A-G-K-L-P-Q-V-M-S-D-L-A-K-G-L-K-A-F-K-E-G-M-K-D-D-G-N-D-N-D-K-T-N-N"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-V-Y-K-Y-Y-D-L-I-R-K-P-I-I-T-E-K-T-T-S-I-S-E-Q-N-K-Y-T-F-Y-V-N-K-F-A-K-K-L-S-L-K-R-A-I-E-A-I-F-K-V-K-V-K-K-V-N-I-L-N-I-K-G-K-K-K-R-F-K-G-I-I-G-T-Q-I-N-R-K-K-A-I-V-T-L-E-K-D-H-N-I-D-Y-A-G-G-I-K"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-I-W-K-G-P-F-V-D-G-Y-L-I-K-K-V-Q-K-L-M-K-S-G-K-S-E-M-I-K-T-W-S-R-R-S-T-I-L-P-I-F-V-G-F-T-F-S-V-H-N-G-N-K-F-I-P-V-Y-I-N-E-E-M-V-G-R-K-L-G-E-F-A-P-T-R-T-F-H-G-H-G-A-D-K-K-V-K-R-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-I-Q-K-N-K-N-F-A-T-A-K-A-K-S-I-R-V-S-P-R-K-L-N-L-V-A-S-F-I-R-N-M-K-V-S-E-A-L-V-Q-L-T-F-S-P-K-R-I-A-K-I-V-K-D-C-L-Q-S-A-I-A-N-A-E-N-N-L-G-L-D-I-D-R-L-I-I-T-K-A-T-V-G-K-S-V-V-M-K-R-I-M-P-R-A-K-G-R-A-T-R-I-N-K-F-F-S-N-L-Y-I-T-V-T-E-K-E-D-N"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-A-P-K-K-Q-K-F-R-K-A-H-K-G-R-V-M-S-K-A-K-A-G-M-T-L-A-F-G-S-F-G-L-K-S-I-D-G-W-R-V-T-A-R-Q-I-E-A-G-R-K-A-A-T-R-C-M-K-R-Q-G-R-L-W-I-R-I-F-P-D-V-P-V-S-K-K-P-A-E-V-R-M-G-K-G-K-G-T-P-E-F-F-A-V-R-V-S-P-G-R-I-M-F-E-I-E-G-V-E-E-N-I-A-L-R-A-L-E-L-A-S-A-K-L-P-V-R-T-R-I-V-R-R-Y-E"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-V-L-Q-G-V-V-I-S-S-K-T-D-K-T-V-T-V-K-V-E-R-K-F-K-H-P-I-Y-K-K-F-V-K-V-S-K-K-Y-A-A-H-D-I-E-N-K-Y-K-E-G-D-K-V-S-I-V-E-S-R-P-I-S-K-T-K-T-W-V-V-L-N-L-E"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-I-L-E-V-A-D-N-S-G-A-K-K-V-M-C-I-K-V-L-G-G-S-H-H-M-M-A-K-L-G-D-V-I-V-V-S-I-K-E-A-I-P-G-G-K-V-K-K-G-D-V-Y-K-G-V-I-V-R-T-K-T-G-V-V-R-S-D-G-S-T-I-K-F-D-K-N-A-L-V-L-L-N-K-Q-D-E-P-I-G-T-R-V-F-G-P-V-T-R-E-L-R-A-K-K-Y-V-R-I-M-S-L-A-E-E-V-L"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-I-K-L-K-V-K-K-G-D-E-V-V-I-I-T-G-K-Y-K-G-K-K-G-K-V-L-K-V-F-P-E-E-N-T-V-V-V-S-G-V-N-L-V-K-K-H-T-K-P-N-K-M-S-E-G-G-I-I-T-Q-E-S-P-I-H-I-S-N-I-A-H-I-D-P-K-T-G-N-P-T-K-V-A-F-K-F-L-E-D-G-S-K-V-R-V-A-K-K-S-G-E-I-I-G-K-V-G-N-N-V-K-V"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-L-R-F-K-E-L-Y-K-Q-K-I-I-E-S-L-K-K-E-F-S-F-K-N-K-H-E-I-P-K-I-K-K-I-V-I-N-M-G-V-G-E-A-I-A-D-S-K-V-I-N-N-A-L-N-D-L-T-L-I-S-G-Q-K-P-V-V-T-L-A-R-K-S-I-A-T-F-K-L-R-E-N-M-K-I-G-C-K-V-T-L-R-K-D-R-M-Y-D-F-L-E-R-L-V-I-V-A-L-P-R-V-K-E-F-R-G-F-S-Y-K-S-F-D-G-K-G-N-F-T-F-G-L-K-E-Q-I-V-F-P-E-I-N-Y-D-K-I-D-T-I-R-G-M-D-I-T-I-V-T-S-A-K-T-D-Q-E-S-K-F-L-L-S-G-F-N-L-P-F-Y-N"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-V-S-S-I-Q-K-N-K-S-R-Q-K-K-S-Q-S-L-H-N-K-R-S-E-L-K-S-K-I-Y-D-K-S-L-S-L-E-Q-R-F-P-L-I-I-A-L-A-Q-L-P-R-N-S-S-S-T-R-I-R-N-R-C-E-L-T-G-R-P-R-G-V-I-R-K-F-G-I-S-R-N-K-L-R-E-L-I-G-R-G-L-V-P-G-V-V-K-A-S-W"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-T-D-N-V-A-D-M-L-T-R-I-R-N-A-Y-K-S-K-L-I-N-V-S-F-P-S-S-K-I-K-T-S-I-L-D-V-L-Q-K-E-G-Y-I-K-D-Y-V-T-T-Q-K-N-N-I-S-Y-T-E-V-A-L-K-Y-S-V-N-G-E-A-S-I-C-E-I-H-R-V-S-K-P-G-K-R-V-Y-S-A-I-K-D-L-K-G-Y-Y-N-N-M-G-I-Y-I-L-S-T-P-Y-G-V-M-S-D-R-E-A-H-I-K-N-V-G-G-E-V-I-C-K-V-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-L-P-I-T-I-P-E-G-V-K-V-G-L-N-D-L-E-V-K-I-S-G-P-K-G-E-L-S-K-T-F-K-G-N-I-A-I-I-M-E-E-N-K-L-V-V-K-P-L-A-V-N-K-N-A-R-A-M-W-G-T-A-R-S-I-I-C-N-M-I-T-G-V-K-E-G-F-K-L-K-L-E-I-N-G-V-G-Y-R-A-M-V-K-G-K-Y-L-N-L-M-L-A-K-S-H-N-T-K-I-E-I-P-S-N-I-K-I-D-L-P-K-Q-N-I-I-L-L-E-G-I-D-K-E-K-L-G-Q-F-A-S-I-I-I-K-Q-R-P-P-E-P-Y-K-G-K-G-I-K-F-E-N-K-F-I-Q-R-K-E-G-K-K-N"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-R-S-A-K-L-K-F-E-K-R-K-S-R-I-R-Y-K-I-S-K-T-S-N-R-M-R-L-S-I-F-K-S-C-R-H-I-Y-A-Q-I-I-D-D-S-K-S-I-T-I-A-A-A-S-T-L-D-K-K-I-K-K-I-K-K-S-H-C-N-I-E-N-A-I-K-V-G-K-E-I-A-K-K-A-D-S-A-G-I-K-E-V-V-F-D-R-G-G-Y-K-Y-H-G-I-I-K-A-L-A-D-A-A-R-E-K-I-K-F"} +{"text": "### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-K-V-K-K-N-E-E-A-L-S-E-V-L-V-D-V-N-R-V-T-K-V-V-K-G-G-R-R-F-A-F-S-A-Y-V-V-V-G-D-K-A-G-R-V-G-A-G-H-G-K-A-K-E-V-N-E-A-R-G-K-A-K-Q-A-A-K-K-R-M-M-K-V-P-L-Y-Q-N-R-T-I-H-H-D-V-V-G-K-S-G-A-A-K-V-I-L-R-R-A-K-A-G-T-G-V-I-A-G-G-S-M-R-A-I-F-D-S-L-G-V-H-D-I-V-A-K-S-I-G-S-T-N-V-Y-A-M-I-S-A-T-F-D-A-L-N-K-L-A-S-P-K-S-I-A-I-R-R-D-K-K-V-H-E-I-S-I-K-S-Y-I-Q-V-N-E"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-E-L-Y-N-N-L-G-A-K-K-N-K-K-R-I-A-R-G-I-G-S-G-K-G-K-T-A-G-R-G-I-K-G-Q-K-S-R-S-G-V-A-I-K-G-F-E-G-G-Q-T-P-M-I-K-R-L-P-K-R-G-F-K-C-I-S-T-K-K-Y-N-I-I-N-I-Y-N-I-E-E-A-L-T-D-G-R-L-S-T-N-D-I-I-T-K-E-K-L-L-E-V-G-L-I-N-N-K-N-L-V-K-L-L-S-I-C-S-D-D-F-A-S-P-L-S-L-K-L-D-A-Y-S-S-K-A-K-Y-L-I-E-K-V-G-G-Q-L-L"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-S-V-N-I-P-D-N-K-R-L-V-V-S-L-T-Y-I-Y-G-L-G-S-T-M-A-A-E-I-C-N-K-A-K-I-S-K-D-K-K-V-K-V-L-T-D-Q-E-L-I-S-L-R-N-I-I-E-N-E-Y-K-V-E-G-D-L-K-R-E-V-T-L-N-I-K-K-K-K-D-I-R-C-Y-Q-G-L-R-H-I-R-K-L-P-V-R-G-Q-N-T-H-S-N-A-R-T-R-K-G-K-A-I-A-I-A-G-K-K-K-T-V-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-N-Q-T-I-K-V-K-K-K-K-K-T-I-T-L-G-V-V-H-I-R-A-S-F-N-N-T-I-V-T-F-T-D-I-Q-G-N-T-I-S-S-A-S-A-G-G-N-G-F-K-G-A-R-K-A-T-P-Y-A-A-Q-V-T-I-D-K-A-S-E-K-A-K-E-C-G-L-K-T-I-S-I-R-I-G-G-P-G-A-Q-R-E-S-A-M-R-A-L-F-G-Q-N-F-V-V-T-S-I-L-D-V-S-S-I-A-H-N-G-V-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-S-S-A-K-K-V-V-R-Q-T-V-K-R-T-L-I-N-K-K-R-S-S-A-I-K-T-F-I-K-K-V-I-H-E-I-S-R-G-N-K-E-D-A-N-L-A-L-S-I-A-Q-S-K-I-M-Q-G-V-K-K-N-I-I-K-L-N-T-A-S-R-K-I-R-R-L-S-K-Q-I-K-N-L-Y-K-S-E"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-K-D-Y-N-I-E-N-N-N-V-E-E-E-N-P-N-V-E-T-Q-V-V-D-N-E-E-I-V-R-L-K-A-E-I-E-E-L-K-D-K-L-I-R-T-T-A-E-I-D-N-T-R-K-R-L-E-K-A-R-D-E-A-K-D-Y-A-I-A-T-F-A-K-E-L-L-N-V-S-D-N-L-A-R-A-L-A-H-K-P-A-N-S-D-V-E-V-T-N-I-I-S-G-V-Q-M-T-K-D-E-L-D-K-I-F-H-K-H-H-I-E-E-I-K-P-A-I-G-S-M-F-D-Y-N-L-H-N-A-I-S-H-I-E-H-P-D-H-E-P-N-S-I-I-T-L-M-Q-S-G-Y-K-I-R-D-R-L-L-R-P-A-A-V-Q-V-V-K-K-P"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-S-F-K-P-L-H-D-R-I-A-I-K-P-I-E-N-E-E-K-T-K-G-G-I-I-I-P-D-T-A-K-E-K-P-M-Q-G-E-I-V-A-V-G-N-G-V-L-N-K-N-G-E-I-H-P-L-E-L-K-V-G-D-K-V-L-Y-G-K-W-A-G-T-E-I-E-I-K-G-E-K-L-I-V-M-K-E-S-D-V-F-G-I-I-N"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-L-C-I-T-S-L-K-N-Q-K-E-F-E-L-I-N-K-L-G-E-K-F-Y-E-R-Y-F-I-L-V-I-A-K-K-L-P-K-I-F-L-E-S-K-Y-N-T-F-L-G-I-K-V-S-R-K-L-N-K-K-A-V-V-R-N-K-I-K-R-R-I-R-H-L-M-R-I-I-V-N-D-S-N-F-K-A-I-K-F-A-I-I-I-I-P-K-K-G-F-E-E-I-N-F-S-H-L-Q-Y-E-L-S-K-I-I-L-R-N-I-Y"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-A-K-S-G-K-I-S-K-K-R-H-K-K-I-L-K-L-A-K-G-Y-R-G-R-A-N-N-C-F-R-V-A-I-E-K-V-E-K-G-L-Q-Y-A-Y-R-D-R-R-N-R-K-R-D-F-R-G-L-W-I-Q-R-I-N-A-A-V-R-E-H-G-L-I-Y-S-Q-F-M-G-A-L-K-K-A-G-I-N-I-D-R-K-V-L-A-E-L-A-V-N-N-N-D-G-F-A-S-I-V-Q-Q-S-K-A-H-I"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-I-L-V-I-G-L-G-N-P-G-T-E-Y-Q-Y-T-R-H-N-I-G-F-I-A-I-E-R-I-A-S-K-Y-H-L-S-F-S-I-K-K-K-F-N-C-E-I-A-E-A-V-I-D-R-Q-K-I-I-F-I-K-P-T-T-Y-M-N-L-S-G-K-S-V-I-L-V-K-T-Y-Y-N-I-K-Y-E-K-V-F-V-I-H-D-D-I-D-L-E-I-G-R-I-K-F-K-T-G-G-G-N-G-G-H-N-G-L-K-S-I-D-V-V-I-G-N-H-Y-N-R-I-R-I-G-I-G-R-P-K-N-N-H-D-V-A-D-Y-V-L-N-N-F-S-E-S-E-Y-K-I-A-M-Q-S-I-D-N-I-A-N-N-F-G-L-I-L-E-H-K-L-A-E-F-T-N-K-I-V"} +{"text": "### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-S-Q-H-T-Q-D-N-Q-I-N-N-N-E-T-I-E-I-Q-E-T-D-T-V-P-V-E-T-N-S-L-Q-S-G-L-T-S-L-I-P-M-I-L-I-F-A-V-F-Y-F-L-L-L-R-P-Q-E-K-R-R-K-E-R-E-K-L-V-S-G-V-K-K-G-E-E-V-L-I-N-S-G-I-Y-G-I-V-T-K-V-S-E-N-D-N-N-I-E-I-E-I-A-K-D-V-R-I-K-A-I-K-S-A-I-V-D-I-T-S-R-K-R-E-V-A-A-T-Q-E-N-N-K-K-N-K-K-V-S-C-A-K-S-S"} +{"text": "### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-A-E-D-C-N-K-I-I-P-D-R-F-R-L-V-V-L-A-T-R-Y-A-K-L-L-N-Y-K-V-E-T-N-Q-I-K-K-E-K-R-D-K-P-P-V-I-S-L-R-R-I-A-A-G-K-V-S-V-P-Q-L-E-Q-D-L-I-N-S-L-R-T-R-M-M-I-E-P-L-I-N-Q-D-E-S-E-D-V-E-E-K-F-E-Y-L-P-E-V-Y-I-G-E-D-Y-S-D-L-D-D-Q-I-F-I-N-E-N-G-E-D-Y-E-T-D-K"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-L-I-G-V-G-T-D-I-V-Q-I-P-R-I-E-K-I-L-N-I-Y-Q-E-L-F-A-K-K-I-L-A-L-K-E-L-K-Q-F-T-L-L-N-K-T-N-H-A-T-F-L-A-K-R-F-S-A-K-E-A-V-S-K-A-F-G-V-G-I-G-R-G-I-N-F-K-D-I-T-I-L-N-D-N-L-G-K-P-T-V-E-I-S-S-H-Y-T-N-K-L-A-P-F-N-I-H-L-S-L-S-D-D-Y-P-I-C-I-A-F-A-I-I-E-S-N-C"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-Q-T-I-A-Q-Q-I-T-N-I-I-E-E-S-L-T-D-M-G-F-E-L-V-L-V-K-F-K-G-V-S-P-K-V-V-E-V-L-I-D-S-L-N-G-N-K-I-S-I-E-D-C-T-N-V-S-R-T-I-S-A-I-L-D-V-E-D-L-I-E-E-A-Y-S-L-E-V-S-S-S-G-I-E-R-T-L-V-K-F-E-N-Y-N-R-F-L-G-R-E-V-K-I-K-L-K-E-L-L-N-G-K-T-L-Y-P-R"} +{"text": "### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-I-K-N-K-K-I-I-I-A-I-S-G-A-S-G-A-I-Y-G-I-R-L-L-K-V-L-K-E-Q-N-I-E-T-H-L-V-I-S-D-G-A-A-L-T-I-K-F-E-T-K-Y-S-I-Q-E-V-K-F-L-A-N-Y-C-Y-D-E-K-N-L-G-A-A-I-S-S-G-S-F-K-T-A-G-M-I-I-A-P-C-S-M-K-T-L-A-S-I-A-H-S-M-E-D-S-L-I-S-R-A-A-G-V-V-L-K-E-R-R-K-L-I-L-M-T-R-E-T-P-L-H-I-G-H-L-E-N-M-L-K-V-A-H-Y-G-G-I-I-A-P-P-I-P-A-F-Y-N-K-P-T-R-I-N-D-I-I-D-H-S-I-T-R-V-L-D-F-F-D-I-E-T-N-L-I-K-R-W-S-S-D"} +{"text": "### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-Y-L-F-I-N-I-I-W-R-N-F-I-S-K-N-N-L-P-K-A-N-R-E-I-K-A-K-E-V-R-L-V-D-E-N-S-E-M-Y-G-V-V-N-I-R-E-A-L-D-M-A-E-R-A-G-L-D-L-V-E-I-S-P-N-A-V-P-P-V-C-K-I-L-D-F-G-K-F-K-Y-E-S-K-K-R-L-H-E-A-R-K-K-Q-K-V-V-V-L-K-E-M-K-F-K-P-N-I-S-I-G-D-F-E-T-K-L-R-K-I-K-E-F-L-K-D-G-D-K-V-K-I-S-L-W-F-K-G-R-E-I-L-H-K-E-V-G-H-E-L-F-K-R-I-E-L-A-L-E-G-L-I-K-I-D-Q-H-A-K-M-E-G-K-Q-M-I-M-I-V-S-P-D-I-K-V"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-V-T-K-N-Y-L-I-D-K-V-H-D-K-L-D-Y-L-S-K-Q-D-V-K-E-S-V-D-L-I-L-D-Y-L-N-E-S-L-K-E-Q-K-R-I-E-I-R-N-F-G-N-F-S-I-R-K-R-K-F-P-E-S-N-K-F-Y-N-T-V-Y-Y-R-M-P-K-N-L-F-K-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-I-T-T-E-R-K-Q-Q-L-I-K-E-Y-A-I-T-E-N-D-T-G-S-T-A-V-Q-C-A-I-L-T-E-R-I-N-N-L-T-E-H-F-K-S-N-H-K-D-H-T-S-R-R-G-L-L-I-L-V-G-R-R-R-R-L-L-N-Y-I-K-K-N-N-V-S-E-Y-L-D-L-I-S-K-L-G-I-R-K-I-K"} +{"text": "### FUNCTION A scaffold on which IscS assembles Fe-S clusters Subsequently gives the nascent cluster to other proteins It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters ### SEQUENCE -M-A-Y-S-K-K-V-I-D-H-Y-E-N-P-R-N-V-G-S-L-D-K-K-K-K-N-V-G-T-G-L-V-G-A-P-A-C-G-D-V-M-K-L-Q-I-E-V-G-D-D-E-I-I-T-D-A-K-F-K-T-F-G-C-G-S-A-I-A-S-S-S-L-V-T-E-W-I-K-G-K-S-V-E-D-A-K-E-I-K-N-T-E-I-A-K-E-L-S-L-P-P-V-K-L-H-C-S-L-L-A-E-D-A-I-K-A-A-I-A-D-Y-K-Q-K-R-E-N-K-K-D-S"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-N-K-T-N-D-I-D-Q-L-I-Y-L-F-S-K-L-P-G-L-G-I-R-S-A-R-R-I-V-L-Y-L-L-Q-D-K-D-V-R-L-K-S-L-I-N-H-L-I-E-L-D-K-K-I-V-K-C-E-I-C-G-N-L-D-T-K-S-I-C-H-I-C-S-S-E-Y-R-D-K-S-T-I-A-I-V-E-T-V-A-E-L-C-A-M-E-R-S-G-N-F-K-G-L-Y-H-V-L-G-H-N-L-S-A-A-S-R-Q-N-P-R-I-L-R-L-P-E-L-L-K-R-C-F-V-E-N-I-K-E-V-I-I-A-T-N-S-T-L-E-G-Q-T-T-A-Y-F-I-I-E-Y-L-K-E-H-P-A-K-I-S-R-L-A-S-G-I-P-I-G-G-E-L-D-Y-L-D-E-G-T-L-S-A-A-I-S-L-R-Q-P-C-E"} +{"text": "### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-L-K-L-L-S-E-I-G-P-V-I-A-F-F-A-G-F-F-Y-G-G-G-I-Q-N-A-T-L-Y-M-L-I-T-S-I-I-C-I-T-L-C-Y-I-I-D-K-K-V-S-K-L-S-I-I-S-S-T-V-L-F-I-S-G-I-I-T-L-I-S-G-D-S-M-Y-I-K-I-K-P-T-I-L-Y-V-I-F-G-I-I-F-L-M-S-G-I-K-K-N-P-F-I-K-Y-A-L-E-S-I-V-R-L-K-E-E-S-W-I-I-L-S-Y-R-T-A-A-F-F-F-F-M-A-V-V-N-E-V-V-W-R-N-F-S-D-E-T-W-V-K-F-K-V-F-G-V-I-P-I-T-F-I-F-I-L-L-Q-L-P-L-L-L-K-N-K-L-P-D-S-K-I"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-K-L-N-G-K-I-D-S-H-C-D-D-Y-V-I-I-D-V-N-G-V-G-Y-L-V-Y-A-S-G-K-T-L-A-K-L-V-E-G-K-F-Y-K-L-F-I-E-T-H-V-R-E-E-H-I-H-L-Y-G-F-L-T-L-E-E-K-N-F-F-N-L-L-Q-S-V-N-G-I-G-T-K-M-A-L-S-I-L-S-N-L-T-P-T-D-I-Q-I-A-I-N-N-D-D-R-N-I-F-K-A-I-S-G-V-G-A-K-L-A-E-R-I-M-L-E-L-K-D-K-I-T-K-I-F-S-S-S-A-I-I-K-D-S-N-I-S-S-I-A-I-N-E-V-M-K-A-L-V-N-L-G-F-T-R-F-E-A-Q-N-T-V-Q-G-I-I-T-Q-N-P-K-I-S-I-D-E-L-I-K-T-A-L-K-N-R-N-S-S-F"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur , and thus conserves the redox energy in a proton gradient ### SEQUENCE -M-T-L-D-K-L-I-E-K-L-A-A-K-F-R-I-V-I-T-K-V-A-V-K-D-H-L-A-Y-K-I-E-P-H-F-L-L-P-F-L-K-A-L-K-E-S-E-E-L-R-F-T-V-L-T-D-L-F-G-V-D-F-P-K-K-E-K-R-F-E-V-V-Y-N-L-L-S-L-K-L-N-K-N-L-I-I-K-T-H-I-S-E-K-E-S-I-P-S-A-M-Q-I-L-S-A-A-Y-W-Y-E-L-E-V-Y-D-M-Y-G-V-N-F-N-G-N-N-D-K-R-R-I-L-T-D-Y-D-F-E-G-H-P-L-R-K-D-F-P-L-T-G-Y-T-Q-V-K-Y-D-K-K-L-E-K-V-T-Y-E-P-V-N-L-D-I-E-Y-R-E-F-D-F-S-S-H-W-H-S-P-S-Y-V-L-P-G-D-E-K-T-E-E"} +{"text": "### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur ### SEQUENCE -M-N-T-K-I-T-N-F-T-F-A-F-D-K-K-N-L-N-L-A-E-T-I-I-K-K-Y-P-P-E-G-K-R-S-A-I-L-P-L-L-D-L-A-Q-R-Q-N-G-G-W-L-H-V-S-A-I-E-Y-V-A-N-M-L-E-M-P-Y-M-R-A-Y-E-V-A-T-F-Y-T-M-F-N-L-N-P-I-G-K-Y-H-I-Q-V-C-T-T-T-P-C-W-L-R-G-S-D-N-I-M-K-I-C-E-K-K-L-A-I-K-H-K-E-T-T-K-D-Q-K-F-T-L-S-E-I-E-C-L-G-A-C-V-N-A-P-V-V-Q-I-N-D-D-Y-Y-E-D-L-N-E-A-K-M-E-K-L-I-E-Q-Y-L-N-E-F-K-S-K-M-Q-N-G"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-T-N-T-K-T-L-K-D-N-I-S-F-E-E-A-L-R-E-L-E-E-I-V-K-K-I-D-T-G-Q-E-N-L-E-T-A-V-N-S-F-E-R-G-I-L-L-K-N-H-C-E-K-K-L-K-E-A-R-L-K-I-E-K-I-T-K-L-A-D-S-T-V-I-L-E-E-T-E-V"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-N-S-L-K-N-L-I-L-I-G-V-I-K-S-C-H-G-I-Q-G-H-V-I-L-K-S-F-T-E-P-S-T-K-I-L-E-R-T-L-V-N-E-S-G-A-N-I-R-I-K-L-I-S-Q-N-A-K-G-E-L-I-C-T-F-N-D-I-A-T-R-N-E-A-E-N-L-K-G-Y-K-I-F-C-L-R-T-S-L-P-K-L-E-E-D-E-F-Y-I-A-D-L-N-H-L-Q-I-L-D-Q-S-N-K-E-I-G-K-I-K-N-I-L-N-F-G-A-G-D-I-I-E-I-E-F-L-D-K-T-T-E-L-L-P-F-N-K-E-F-F-P-I-I-T-K-D-Y-V-I-L-N-Y-Q-T-K-V"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-I-I-K-N-L-Q-E-F-Y-R-L-L-I-P-N-K-P-L-I-A-I-D-Y-G-S-K-K-I-G-V-A-L-S-D-Q-E-L-S-I-A-M-P-F-N-T-I-T-A-V-N-K-K-V-V-I-T-S-L-L-N-I-I-K-K-Y-K-V-C-G-I-V-I-G-L-P-I-D-M-S-G-G-V-T-Q-Q-T-N-I-V-M-K-F-A-E-K-L-K-Q-S-L-G-L-P-I-Y-L-Q-D-E-R-L-T-T-K-S-A-N-N-F-L-K-S-F-G-I-K-R-K-D-R-N-H-N-D-D-A-V-A-A-S-M-I-L-E-I-V-L-N-A-I-K-R-F-N-L"} +{"text": "### FUNCTION Probable biotin transporter ### SEQUENCE -M-R-Y-I-M-N-S-L-F-K-I-L-Y-L-N-R-F-V-E-Y-L-S-T-N-T-Y-I-L-D-I-V-K-I-V-M-G-V-I-A-I-F-A-S-S-Q-I-T-I-P-I-K-P-V-A-I-T-M-H-S-V-I-L-C-I-I-A-F-T-Y-S-P-R-L-S-F-L-T-I-L-T-F-I-F-I-G-V-M-G-L-P-V-F-C-Q-F-S-S-G-I-N-Y-F-L-G-S-A-G-G-Y-Y-L-G-F-L-I-G-M-P-V-M-S-V-L-K-G-K-L-A-E-N-Y-L-N-V-T-I-I-C-I-I-G-H-A-I-F-Y-L-C-G-I-I-W-L-A-S-M-I-G-L-K-Q-A-I-Y-S-G-F-I-I-F-I-P-S-G-L-V-K-I-L-I-F-S-C-L-F-S-Y-I-K-N-L-K-R-K"} +{"text": "### FUNCTION Involved in iron-sulfur cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-N-T-A-F-S-K-L-A-E-T-T-I-V-Y-I-V-D-K-I-E-E-Q-D-L-E-G-I-I-D-V-D-L-Q-G-D-I-L-N-L-D-T-E-N-G-I-Y-V-I-N-T-Q-S-A-S-K-E-I-W-L-S-S-P-V-S-G-P-H-H-F-F-Y-E-Q-G-K-W-K-S-R-I-G-F-E-L-M-V-L-L-T-E-E-L-G-I-R-F-D-K-Y-E-I-F"} +{"text": "### FUNCTION Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I ### SEQUENCE -M-S-K-K-S-N-K-N-L-A-F-S-L-L-G-L-M-M-S-M-V-L-L-S-F-A-S-V-P-I-Y-N-L-F-C-K-V-T-G-Y-G-G-T-T-I-K-E-T-V-S-V-Y-S-K-V-K-G-T-K-A-I-I-I-E-F-D-A-N-V-D-P-N-L-P-W-H-F-I-P-R-Q-K-R-V-Q-I-V-P-G-Q-N-T-L-V-F-Y-E-A-E-N-L-S-N-K-D-I-I-G-T-S-I-Y-N-V-T-P-N-K-A-G-K-Y-F-V-K-I-H-C-F-C-F-E-E-Q-L-L-K-A-R-E-K-V-L-M-P-V-T-F-Y-I-D-N-D-F-E-R-D-P-E-M-E-N-I-K-V-I-T-L-S-Y-S-F-F-K-I-R-E-L"} +{"text": "### FUNCTION May be involved in electron transfer from bc1 complex to aa3 ### SEQUENCE -M-T-G-K-E-L-N-K-I-V-A-A-I-L-F-A-S-L-I-A-M-I-V-G-F-I-A-N-I-L-Y-K-P-N-L-H-V-L-H-R-G-Y-S-I-A-I-Q-K-S-S-S-N-E-S-A-T-V-I-A-Q-E-S-V-N-I-Q-E-L-M-K-T-A-N-A-N-H-G-R-E-I-A-K-K-C-L-M-C-H-S-L-D-K-D-G-P-N-K-L-G-P-H-L-W-N-I-V-G-R-P-K-A-S-I-T-D-Y-K-Y-S-F-A-I-S-K-L-G-G-V-W-D-D-E-N-L-F-A-F-L-H-K-P-S-S-Y-A-P-G-T-K-M-S-F-A-G-I-S-K-P-Q-D-I-A-D-V-I-L-F-L-K-N-Y-V-H-D-Q"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-I-S-A-N-S-I-R-T-G-N-I-L-V-Y-N-N-D-L-W-V-V-S-K-T-P-E-H-T-Q-P-G-K-G-G-A-Y-V-Q-V-E-M-K-N-L-K-T-G-T-K-R-N-D-R-F-S-S-S-D-Y-L-E-K-A-E-L-E-Q-K-D-C-Q-F-L-Y-F-E-G-N-N-L-V-L-M-D-T-K-H-F-D-Q-I-N-V-P-K-E-I-L-E-A-K-L-P-F-L-T-E-N-M-I-V-K-V-E-F-Y-N-D-K-P-L-T-I-V-L-P-P-T-V-I-L-A-I-S-E-T-D-P-V-I-K-G-A-T-V-T-S-S-Y-K-P-A-I-L-E-N-G-I-K-V-K-V-P-Q-Y-L-A-I-G-E-K-I-V-V-K-T-D-D-M-T-Y-V-E-R-A-K"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-Y-S-A-K-P-S-E-I-E-K-K-W-W-V-I-D-A-K-N-V-V-L-G-R-L-A-S-R-V-A-I-M-L-R-G-K-H-K-P-S-F-T-P-H-L-D-C-G-D-N-I-I-I-I-N-A-E-H-I-K-L-T-G-K-K-L-N-P-K-D-G-K-V-Y-Y-R-H-T-G-F-P-G-G-I-K-D-T-T-A-G-K-I-L-S-G-K-Y-P-E-R-V-I-K-M-A-V-K-R-M-I-T-R-N-V-L-G-A-K-Q-M-S-N-L-Y-V-Y-A-N-C-E-H-P-H-M-A-Q-Q-P-T-I-Y-D-F-A-S-E-N-P-K-N-K-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-I-F-S-I-V-T-A-P-D-E-R-L-K-Q-K-S-K-P-V-L-E-C-T-D-Q-T-R-K-F-M-H-D-M-L-E-T-M-Y-N-A-D-G-A-G-L-A-A-V-Q-V-G-I-L-L-R-I-L-V-I-D-I-K-E-Y-D-P-V-E-R-P-K-D-F-Y-P-L-F-I-V-N-P-E-I-I-E-K-S-T-E-L-V-T-A-N-E-G-C-I-S-L-P-K-Q-R-I-E-V-T-R-P-E-S-V-K-I-R-Y-L-D-Y-H-G-K-S-Q-E-L-K-A-N-D-W-L-A-R-V-I-Q-H-E-Y-D-H-L-E-G-K-L-M-V-D-Y-L-S-N-L-K-R-D-V-V-L-R-K-L-K-K-L-K-N-N-I-V"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-N-K-S-I-L-H-T-I-I-I-Y-T-L-A-S-C-P-Y-C-I-K-A-K-A-L-L-D-K-K-N-V-I-Y-E-E-I-E-V-S-N-L-T-Q-E-E-K-E-K-F-I-K-K-S-G-G-K-S-T-V-P-Q-I-F-I-D-N-M-H-V-G-G-C-D-D-L-F-N-L-E-K-E-G-R-L-D-K-L-L-E-H-Q-P-K-N"} +{"text": "### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-Q-N-Y-F-Q-L-L-E-L-P-Q-E-Y-N-I-D-L-K-I-L-E-K-Q-Y-F-A-M-Q-V-K-Y-H-P-D-T-A-K-T-A-Q-E-K-A-Q-N-L-I-T-S-T-E-L-N-K-A-Y-S-T-L-K-D-A-L-K-R-A-E-Y-M-L-L-L-Q-N-I-N-L-N-D-E-K-I-R-S-L-L-S-P-L-E-L-S-I-F-W-D-E-M-E-R-I-E-N-T-T-L-F-S-D-L-E-K-L-K-N-K-Y-E-L-M-Q-Q-Q-N-I-N-S-L-K-Q-A-F-V-E-Q-N-L-S-D-A-T-I-Y-T-S-K-L-K-Y-I-R-T-L-Q-S-K-L-Q-E-K-I-K-S-C-K"} +{"text": "### FUNCTION Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-L-R-K-I-K-V-T-F-I-I-N-D-E-E-E-R-T-V-E-A-P-I-G-L-S-I-L-E-I-A-H-S-N-D-L-D-L-E-G-A-C-E-G-S-L-A-C-A-T-C-H-V-M-L-E-E-E-F-Y-N-K-L-K-K-P-T-E-A-E-E-D-M-L-D-L-A-F-G-L-T-D-T-S-R-L-G-C-Q-I-I-L-T-E-E-L-D-G-I-K-V-R-L-P-S-A-T-R-N-I-K-L"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-E-F-I-A-F-M-T-E-H-G-H-N-N-K-H-A-A-H-K-T-L-T-K-A-D-A-E-K-A-L-N-L-V-I-E-S-V-I-S-A-I-K-S-K-H-N-V-N-L-T-G-F-G-S-F-E-I-H-H-R-K-E-R-E-G-R-N-P-K-T-G-A-K-M-K-I-D-A-Y-N-Q-P-T-F-R-A-G-R-K-L-K-E-A-C-N"} +{"text": "### FUNCTION Specifically methylates the N3 position of the uracil ring of uridine 1498 ### SEQUENCE -M-K-Y-N-R-I-Y-I-N-S-N-L-A-E-N-S-K-L-E-L-A-R-D-Y-V-H-Y-V-K-T-V-L-R-L-K-I-H-D-S-L-R-I-F-N-G-S-D-G-E-F-L-A-Q-I-T-Q-I-G-K-N-N-L-S-V-V-L-K-E-Q-L-K-K-A-Y-I-E-S-A-L-T-L-A-V-A-I-I-K-S-D-K-L-M-L-T-I-N-M-A-T-Q-L-G-I-T-K-I-I-P-L-I-T-R-R-C-Q-F-R-T-V-N-I-E-R-L-M-K-C-V-I-E-A-T-E-Q-S-E-R-L-N-P-P-I-I-E-Q-A-I-T-L-K-D-Y-L-K-K-N-N-N-L-I-L-Y-A-N-E-H-E-K-V-K-H-S-I-L-H-I-S-S-L-L-S-K-D-I-A-I-I-I-G-P-E-E-G-L-L-M-M-S"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-L-S-F-Q-H-T-K-I-L-P-Y-K-P-K-K-L-F-D-L-V-W-D-I-K-S-Y-P-Q-F-L-P-W-C-A-A-A-R-I-I-S-E-N-N-Q-E-V-I-S-E-L-V-I-Q-L-K-G-L-S-E-K-Y-N-S-R-V-I-N-T-I-T-D-N-G-I-Y-L-I-D-T-V-A-I-S-G-P-F-E-Y-L-K-S-T-W-Q-F-I-P-H-S-T-G-T-E-L-K-F-F-I-N-F-K-M-T-S-V-I-L-D-K-L-I-G-S-Y-F-T-I-A-T-E-K-M-I-L-A-F-E-K-R-A-K-E-V-I-K"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-S-T-N-K-I-N-K-K-S-I-A-R-I-A-A-V-Q-A-L-Y-Q-N-I-L-Q-N-N-Y-D-M-Y-D-I-M-Q-N-I-L-A-C-Y-H-S-N-N-S-I-D-L-P-K-N-F-K-I-S-L-S-I-S-H-F-K-M-L-V-K-S-V-F-E-N-I-N-K-L-D-E-I-I-D-N-H-L-T-N-A-K-D-S-V-H-M-P-I-L-L-R-A-L-L-R-V-S-I-C-E-L-L-F-C-S-T-T-P-A-K-V-V-I-N-E-Y-T-D-I-A-N-D-L-L-N-E-H-E-I-G-F-V-N-S-I-L-D-K-I-A-Q-E-N-N-K-I-S"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-E-K-D-N-L-K-K-I-L-Q-E-K-M-E-K-A-I-K-V-L-G-N-E-L-K-G-L-R-T-G-R-A-S-I-N-F-L-D-S-V-T-V-E-A-Y-G-S-K-I-P-L-S-Q-V-A-S-L-S-T-P-D-A-R-T-I-N-V-Q-V-W-D-K-S-M-V-S-S-V-E-K-G-I-T-I-A-N-L-G-L-T-H-A-T-D-G-Q-L-I-R-L-P-I-P-S-L-T-E-E-R-R-K-E-L-V-K-L-A-H-K-Y-G-E-E-T-K-I-S-L-R-N-I-R-R-D-G-I-E-E-L-K-K-L-E-K-D-N-I-I-V-K-D-E-Y-H-N-L-S-E-Q-I-Q-K-L-T-D-E-Y-S-S-K-V-D-S-A-I-K-Q-K-E-Q-E-I-M-T-V"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-I-T-K-E-E-A-Q-K-I-A-K-L-A-R-L-K-F-E-K-D-I-V-E-K-F-S-T-Q-L-S-T-I-M-N-M-I-N-I-L-N-E-I-D-C-K-D-I-E-P-L-T-S-V-S-N-M-N-A-R-M-R-E-D-T-V-T-S-S-D-L-S-N-K-L-F-D-N-V-S-G-N-S-A-K-L-A-K-E-V-K-Y-F-I-T-P-K-V-V-E"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-D-L-A-K-I-E-E-Q-L-S-S-L-T-L-M-Q-A-A-E-L-V-K-M-L-E-E-K-W-G-V-S-A-A-A-P-I-T-V-A-S-A-G-V-A-A-P-L-A-E-A-V-T-E-K-T-E-F-E-V-V-L-T-A-T-G-D-K-K-V-E-V-I-K-I-V-K-D-I-T-G-L-G-L-I-E-A-K-K-L-V-D-E-A-P-K-S-I-K-N-N-V-K-K-A-E-A-E-E-I-K-S-K-L-E-A-A-G-A-K-V-E-L-K"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-L-R-S-E-K-P-V-A-V-E-D-I-V-N-I-Y-K-E-S-P-S-V-I-I-T-H-Y-H-G-L-T-V-S-Q-V-S-S-L-R-E-E-L-K-S-K-E-A-G-F-K-V-V-K-N-T-L-A-K-I-A-A-K-Q-T-G-L-D-S-I-T-N-L-F-A-G-P-T-A-I-V-Y-S-K-E-P-V-E-M-A-R-L-V-V-N-F-A-N-S-N-D-N-L-K-I-I-G-G-I-V-D-N-H-I-L-D-A-Y-S-I-K-E-L-S-K-L-P-S-L-H-E-L-R-G-K-I-V-G-L-L-Q-A-P-A-T-K-V-V-G-V-L-Q-A-T-S-S-S-I-A-R-V-I-H-A-H-A-I-K-H"} +{"text": "### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-S-K-K-A-I-K-G-Y-I-N-L-I-I-P-A-A-G-A-T-P-A-P-P-I-G-P-A-L-G-Q-R-K-V-N-I-A-A-F-C-K-D-F-N-D-A-T-N-G-M-E-K-G-V-P-L-P-T-V-I-T-V-Y-E-D-S-S-F-S-F-K-V-K-T-P-P-A-S-Y-F-L-K-K-Y-A-K-I-T-K-G-S-S-A-T-K-K-E-A-M-V-G-K-V-T-I-D-D-C-R-E-I-A-K-L-K-I-S-D-L-N-T-K-N-I-E-A-A-T-K-I-I-C-G-S-A-A-S-M-G-L-E-V-V-G-N"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-I-I-D-N-F-E-Q-E-N-I-A-K-L-T-A-N-K-K-I-P-D-F-E-A-G-D-T-V-K-V-T-V-K-I-I-D-K-A-I-E-K-D-G-K-E-K-L-T-E-R-F-Q-A-Y-E-G-V-V-I-A-K-R-N-R-G-I-T-S-S-F-L-V-R-K-I-S-H-G-E-G-V-E-R-R-F-M-T-Y-S-P-I-V-H-S-I-D-V-V-K-Y-G-V-V-R-R-A-K-L-Y-Y-L-R-H-R-N-G-K-A-A-R-I-R-E-K-L-I-S-R-A-K-P-K-T-A-I-S"} +{"text": "### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-N-G-I-H-P-E-Y-K-K-L-L-I-K-V-G-S-N-I-F-E-T-M-S-T-H-P-I-G-E-I-L-M-D-V-D-F-R-K-H-P-A-W-N-K-D-S-G-N-V-V-N-Q-S-N-K-S-V-S-D-F-N-K-R-F-A-G-L-S-F-D-S-K-K-E-A-S"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-I-D-I-F-L-F-V-H-I-T-I-S-I-L-L-I-I-V-I-L-M-Q-R-S-G-S-G-G-I-S-G-I-S-G-D-N-N-M-G-V-V-S-A-K-T-V-G-N-F-L-S-K-S-T-I-I-L-T-T-L-F-L-I-N-A-I-V-L-A-N-L-S-A-K-K-Q-S-D-L-V-S-K-I-N-E-I-E-E-N-Q-A-D-N-S-L-P-I-A-K"} +{"text": "### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-T-I-N-T-D-T-S-E-A-M-P-H-I-S-V-N-A-Q-Y-I-K-D-L-S-L-E-N-P-S-A-P-S-S-L-A-A-L-D-Q-R-P-Q-I-D-L-S-L-D-I-N-I-T-N-L-S-E-E-N-F-Y-E-V-E-L-N-I-E-A-I-A-R-N-E-K-Y-K-L-F-Q-I-E-L-K-Y-A-G-V-F-N-L-I-N-I-D-S-E-Q-H-P-I-L-L-S-V-H-C-P-A-M-I-F-P-F-A-R-K-I-I-A-S-C-T-Q-D-A-G-F-Q-P-L-M-I-D-P-I-D-F-G-A-L-Y-H-K-K-M-S-E-H-Q-N"} +{"text": "### FUNCTION Specifically methylates the N7 position of guanine in position 527 of 16S rRNA ### SEQUENCE -M-K-V-Q-S-E-I-I-E-K-L-E-I-F-Q-N-L-I-K-K-W-N-K-S-I-N-L-I-S-D-N-T-I-P-N-F-W-Q-R-H-I-L-D-S-L-Q-L-M-Q-Y-I-S-N-K-E-I-H-L-I-D-I-G-S-G-A-G-F-P-G-I-V-L-S-I-A-G-V-T-K-V-S-L-I-E-A-D-L-R-K-C-I-F-L-A-K-A-S-K-I-S-N-N-S-I-Q-I-I-N-Q-R-I-E-K-I-E-I-D-C-S-I-L-T-C-R-A-F-S-N-L-N-T-I-F-N-Y-T-Q-N-I-S-V-R-E-K-F-L-L-L-K-G-K-S-Y-L-T-E-I-V-E-A-K-E-R-W-S-F-D-Y-L-I-H-Q-S-I-T-C-G-S-G-K-I-L-E-I-N-N-L-T-K-I-I"} +{"text": "### FUNCTION This protein catalyzes the committed step to the synthesis of the acidic phospholipids ### SEQUENCE -M-R-I-D-K-N-L-P-N-Y-L-T-I-A-R-I-M-V-I-P-V-I-I-L-L-F-Y-I-N-N-S-L-A-R-K-L-G-A-L-L-F-V-L-A-S-I-T-D-F-F-D-G-Y-I-A-R-K-Y-N-L-V-T-S-F-G-K-M-F-D-P-I-A-D-K-L-L-V-G-C-V-T-I-M-L-L-K-K-D-N-V-D-E-I-P-C-L-L-I-L-A-R-E-F-L-V-S-G-L-R-E-F-L-A-L-V-K-V-S-V-P-V-S-R-L-A-K-L-K-T-F-L-Q-M-F-A-L-S-I-L-I-L-G-S-K-G-S-G-I-I-Y-L-D-I-V-G-E-I-I-L-W-I-A-A-F-L-T-I-I-T-G-Y-S-Y-F-K-A-C-K-T-Y-F"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-V-I-L-I-K-P-V-R-K-L-G-K-I-G-D-I-L-K-V-A-D-G-F-G-R-N-Y-L-L-P-Q-K-L-A-I-R-A-T-K-S-N-K-E-L-I-V-K-Q-K-Y-E-F-E-E-K-D-K-Q-V-R-E-E-V-E-K-I-N-T-I-I-K-D-Q-Q-L-V-F-I-R-Q-T-S-D-D-C-K-L-F-G-S-V-T-N-K-D-I-A-D-K-L-S-K-N-I-S-Y-N-I-S-H-S-N-I-I-L-D-K-Q-I-K-S-T-G-I-Y-T-V-E-I-R-L-H-A-E-L-T-S-I-V-T-V-V-V-A-R-S-E-S-E-A-Q-D-Y-L-R-E-Q-K-A-E-T-L-E-D-V-D-E-T-A"} +{"text": "### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-L-K-S-N-N-A-S-E-T-A-T-S-K-G-V-D-K-A-A-K-K-V-F-F-R-R-R-K-G-C-P-L-S-V-P-N-A-P-V-I-D-Y-K-N-P-E-L-L-I-K-F-V-S-E-G-G-R-M-L-P-S-R-I-T-N-V-C-A-K-K-Q-R-K-L-N-N-A-I-K-I-A-R-I-L-A-L-L-P-F-V-F-Q-A-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-F-Y-E-S-V-F-I-I-R-Q-D-V-S-L-N-D-I-D-K-I-V-D-D-F-T-K-I-I-K-D-N-N-G-T-I-I-K-K-E-Y-W-G-L-R-T-L-A-Y-K-I-G-N-N-K-K-G-H-Y-Y-F-L-G-I-D-I-T-S-N-V-K-E-E-L-E-R-K-M-K-L-N-E-N-I-I-R-F-L-T-I-K-A-D-S-I-S-S-E-P-S-P-I-L-K-N-Q-S-T-E-N-T-P-V-I-D-V-T-I-N-N"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-F-L-D-E-S-F-W-L-T-I-S-F-V-I-F-V-Y-L-I-Y-R-P-A-K-K-A-I-L-N-A-L-D-T-K-I-S-E-I-Q-E-K-V-L-K-A-K-K-L-K-E-D-A-A-L-L-F-E-Q-T-K-L-Q-I-Q-K-L-E-T-L-R-S-Q-M-I-E-E-S-D-K-A-T-K-Q-I-I-Q-D-K-T-K-E-M-E-E-F-L-E-R-K-K-A-D-A-I-Q-L-I-Q-N-Q-K-S-T-A-S-K-D-L-Q-D-E-F-C-D-E-V-I-T-L-V-S-K-Y-F-R-S-A-K-L-S-E-K-S-I-A-K-N-L-M-D-K-S-D-F-V-H-N-D-S-K-A-T-Y-L-H"} +{"text": "### FUNCTION Required for the formation of a threonylcarbamoyl group on adenosine at position 37 ### SEQUENCE -M-H-T-L-N-S-K-K-E-T-K-N-F-A-K-L-F-A-Q-N-L-K-P-N-D-I-V-L-L-N-G-D-L-G-A-G-K-T-F-F-C-R-E-I-I-K-H-F-C-G-K-N-T-N-I-I-S-P-T-F-N-L-L-Q-I-Y-K-T-P-K-F-N-I-Y-H-Y-D-M-Y-R-I-K-S-P-E-E-I-Y-E-L-G-F-E-E-A-L-N-G-N-L-I-L-I-E-W-S-E-I-I-K-H-L-L-T-P-P-L-I-E-V-N-L-K-V-L-D-N-N-K-R-L-C-S-I-H-K-E-N-F-L-F-D-F-L"} +{"text": "### FUNCTION Component of the thioredoxin-thioredoxin reductase system Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-V-N-N-V-T-D-S-S-F-K-N-E-V-L-E-S-D-L-P-V-M-V-D-F-W-A-E-W-C-G-P-C-K-M-L-I-P-I-I-D-E-I-S-K-E-L-Q-D-K-V-K-V-L-K-M-N-I-D-E-N-P-K-T-P-S-E-Y-G-I-R-S-I-P-T-I-M-L-F-K-N-G-E-Q-K-D-T-K-I-G-L-Q-Q-K-N-S-L-L-D-W-I-N-K-S-I"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -L-K-N-I-M-P-E-L-E-V-R-S-R-R-I-G-G-Q-K-Y-Q-I-P-S-E-V-R-P-E-R-K-Q-S-L-G-L-R-W-L-V-Q-F-A-Q-K-R-N-E-K-T-M-Q-Q-K-L-A-K-E-I-I-D-A-A-S-G-N-G-L-A-V-K-K-R-E-E-I-H-R-M-A-E-A-N-K-S-F-A-H-Y-R-W"} +{"text": "### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-R-N-L-E-E-C-R-K-T-E-R-F-V-E-A-E-N-G-N-W-D-S-T-R-L-V-L-A-D-D-N-V-G-F-S-F-N-I-T-R-I-H-P-G-T-E-T-H-I-H-Y-K-H-H-F-E-A-V-F-C-Y-E-G-E-G-E-V-E-T-L-A-D-G-K-I-H-P-I-K-A-G-D-M-Y-L-L-D-Q-H-D-E-H-L-L-R-G-K-E-K-G-M-T-V-A-C-V-F-N-P-A-L-T-G-R-E-V-H-R-E-D-G-S-Y-A-P-V-D"} +{"text": "### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate with acetyl coenzyme A ### SEQUENCE -M-T-P-T-T-E-N-F-T-P-S-A-D-L-A-R-P-S-V-A-D-T-V-I-G-S-A-K-K-T-L-F-I-R-K-P-T-T-D-D-G-W-G-I-Y-E-L-V-K-A-C-P-P-L-D-V-N-S-G-Y-A-Y-L-L-L-A-T-Q-F-R-D-T-C-A-V-A-T-D-E-E-G-E-I-V-G-F-V-S-G-Y-V-K-R-N-A-P-D-T-Y-F-L-W-Q-V-A-V-G-E-K-A-R-G-T-G-L-A-R-R-L-V-E-A-V-L-M-R-P-G-M-G-D-V-R-H-L-E-T-T-I-T-P-D-N-E-A-S-W-G-L-F-K-R-L-A-D-R-W-Q-A-P-L-N-S-R-E-Y-F-S-T-G-Q-L-G-G-E-H-D-P-E-N-L-V-R-I-G-P-F-E-P-Q-Q-I"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-Q-E-E-N-Q-H-P-E-Q-D-D-I-S-E-A-Q-D-A-G-A-A-G-S-L-D-A-R-I-A-E-L-E-A-Q-L-A-E-Q-Q-A-N-V-L-Y-V-K-A-E-G-E-N-I-R-R-R-A-A-E-D-I-D-K-A-R-K-F-A-L-E-K-F-S-S-E-L-L-A-V-K-D-S-L-D-A-A-L-V-V-E-N-A-T-V-E-S-Y-K-S-G-V-E-L-T-A-K-Q-L-L-S-V-F-E-K-F-H-I-T-E-I-N-P-L-G-E-K-F-D-P-N-K-H-Q-A-I-S-M-L-E-S-D-Q-E-P-N-S-V-I-S-V-L-Q-N-V-R-P-E"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-L-R-P-L-H-D-R-V-I-V-K-R-L-D-Q-E-T-K-T-A-S-G-I-V-I-P-D-A-A-A-E-K-P-D-Q-G-E-V-L-A-I-G-P-G-K-R-D-D-K-G-A-L-I-A-L-D-V-K-V-G-D-R-V-L-F-G-K-Y-A-G-Q-T-V-K-V-D-G-Q-E-L-L-V-M-R-E-E-D-I-M-A-V-V-N-A-K"} +{"text": "### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-L-R-P-L-H-D-R-V-I-V-K-R-L-D-Q-E-T-K-T-A-S-G-I-V-I-P-D-A-A-A-E-K-P-D-Q-G-E-V-L-A-I-G-P-G-K-R-D-D-K-G-A-P-I-A-L-D-V-K-V-G-D-R-V-L-F-G-K-Y-A-G-Q-T-V-K-V-D-G-Q-E-L-L-V-M-R-E-E-D-I-M-A-V-V-N-A-K"} +{"text": "### FUNCTION Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase ### SEQUENCE -M-V-Q-R-G-S-K-V-R-I-L-R-P-E-S-Y-W-F-Q-D-I-G-T-V-A-S-I-E-Q-G-G-T-I-R-Y-P-V-I-V-R-F-D-K-V-N-Y-A-G-V-N-T-N-N-F-A-E-Y-E-L-V-E-V-E-A-P-K-A-K-P-K-K"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-A-H-V-T-S-V-T-L-G-E-H-L-T-G-F-V-G-E-M-I-Q-S-G-R-Y-G-N-I-S-E-V-L-R-D-A-L-R-L-M-E-A-R-E-Q-R-V-Q-H-V-R-D-M-V-L-A-G-T-N-V-P-V-S-H-R-L-M-D-E-I-F-S-A-A-V-K-D-T-S-V"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-H-I-T-L-L-C-V-G-K-L-K-E-D-F-L-L-L-A-Q-K-E-Y-L-K-R-L-S-P-Y-A-R-I-E-L-V-E-V-R-E-E-S-L-P-A-S-G-R-A-G-A-L-E-A-V-L-K-K-E-G-T-R-L-L-E-R-I-P-D-N-C-V-T-I-A-L-D-R-K-G-M-M-L-S-S-K-E-F-A-G-Y-L-A-E-L-G-L-R-G-Q-N-K-L-C-F-I-I-G-G-S-A-G-L-A-G-D-V-L-A-R-A-S-L-R-L-S-F-S-K-F-T-F-P-H-Q-L-M-R-I-I-L-L-E-Q-I-Y-R-A-F-K-I-I-R-G-E-K-Y-H-L"} +{"text": "### FUNCTION Involved in the decoration of cell wall teichoic acid with galactose and glucose ### SEQUENCE -M-S-K-I-R-Q-L-L-N-K-I-P-W-Y-T-D-Q-V-H-S-I-F-M-Y-L-I-M-G-G-F-T-T-I-I-N-I-V-T-F-W-L-C-T-Y-I-L-N-W-D-Y-R-I-A-N-T-I-A-F-I-A-S-V-L-F-A-Y-F-S-N-K-K-F-V-F-D-S-Y-T-P-T-W-K-D-R-L-R-E-A-S-S-F-F-G-F-R-C-L-T-Y-I-I-D-I-L-V-M-I-L-L-I-S-Y-L-S-V-D-E-L-W-A-K-I-W-T-N-I-I-V-L-V-L-N-Y-V-F-S-K-W-I-I-F-K-V-Q-K"} +{"text": "### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-H-L-A-L-K-D-L-F-S-G-F-F-V-I-D-D-E-E-E-V-E-V-P-D-K-Q-Q-Q-V-N-E-A-P-A-K-E-Q-S-Q-Q-T-T-K-Q-N-A-I-K-S-V-P-Q-K-S-A-S-R-Y-T-T-T-S-E-E-R-N-N-R-M-S-N-Y-S-K-N-N-S-R-N-V-V-T-M-N-N-A-T-P-N-N-A-S-Q-E-S-S-K-M-C-L-F-E-P-R-V-F-S-D-T-Q-D-I-A-D-E-L-K-N-R-R-A-T-L-V-N-L-Q-R-I-D-K-V-S-A-K-R-I-I-D-F-L-S-G-T-V-Y-A-I-G-G-D-I-Q-R-V-G-T-D-I-F-L-C-T-P-D-N-V-E-V-A-G-S-I-T-D-H-I-E-N-M-E-H-S-F-D"} +{"text": "### FUNCTION Protect the producing cell against microcin E492 ### SEQUENCE -M-T-L-L-S-F-G-F-S-P-V-F-F-S-V-M-A-F-C-I-I-S-R-S-K-F-Y-P-Q-R-T-R-N-K-V-I-V-L-I-L-L-T-F-F-I-C-F-L-Y-P-L-T-K-V-Y-L-V-G-S-Y-G-I-F-D-K-F-Y-L-F-C-F-I-S-T-L-I-A-I-A-I-N-V-V-I-L-T-I-N-G-A-K-N-E-R-N"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-L-C-M-S-A-A-D-I-I-R-E-Q-A-E-Q-H-G-I-A-R-V-T-D-V-W-L-E-V-G-A-L-A-D-V-E-E-S-A-L-H-F-C-F-D-I-A-C-R-D-T-V-A-Q-G-C-T-L-H-I-D-V-I-P-A-Q-A-W-C-W-D-C-S-R-E-A-E-I-M-Q-H-A-G-C-C-P-H-C-G-S-E-R-L-R-I-S-E-G-D-D-L-R-V-K-S-L-E-G-E"} +{"text": "### FUNCTION Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates ### SEQUENCE -M-R-L-G-R-R-T-S-K-Q-E-E-A-Q-I-D-L-T-S-M-L-D-I-V-F-I-M-L-I-F-F-I-V-T-S-S-F-V-R-E-S-G-V-E-V-N-R-P-T-A-A-H-A-V-S-Q-K-Q-A-G-I-F-V-A-I-T-A-A-N-D-I-Y-I-D-K-R-Q-V-D-V-E-R-V-Q-A-T-L-E-H-L-L-L-D-Q-P-D-A-S-L-V-I-Q-A-D-E-H-A-F-N-G-T-V-V-K-V-M-D-A-A-K-G-A-G-V-K-S-I-A-L-A-A-E-K-P"} +{"text": "### FUNCTION RuBisCO catalyzes two reactions the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate Both reactions occur simultaneously and in competition at the same active site Although the small subunit is not catalytic it is essential for maximal activity ### SEQUENCE -M-K-L-T-Q-G-C-F-S-F-L-P-D-L-T-D-D-Q-I-Y-K-Q-V-Q-Y-C-L-A-K-G-W-A-V-N-I-E-F-T-D-D-P-H-P-R-N-T-Y-W-E-M-W-G-L-P-M-F-D-L-Q-D-A-A-G-V-M-M-E-L-A-E-C-R-R-V-Y-G-D-R-Y-I-R-I-S-G-F-D-S-S-P-G-W-E-S-V-R-I-S-F-L-V-N-R-P-P-Q-E-A-E-F-E-L-V-R-Q-E-V-G-G-R-A-I-R-Y-T-T-V-R-K-A-P-A-H-V-S"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-P-R-L-K-T-R-R-E-K-R-L-R-R-H-K-R-I-R-K-K-V-F-G-T-P-E-R-P-R-L-C-V-Y-R-S-L-N-H-F-Y-A-Q-I-I-D-D-T-I-G-H-T-L-V-S-A-S-T-L-D-P-E-F-E-K-I-T-G-K-R-G-G-K-S-I-K-D-A-E-V-V-A-E-I-I-A-R-R-A-L-E-K-G-I-K-K-V-V-F-D-R-G-G-F-K-Y-H-G-K-I-K-A-F-A-D-K-C-R-E-M-G-L-E-F"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-L-V-K-K-P-I-P-Y-P-E-N-V-K-V-S-Y-D-E-K-E-H-K-V-T-V-E-G-P-K-G-K-L-E-L-N-I-H-P-D-I-K-V-T-L-N-Q-Q-E-R-W-I-K-L-D-R-P-S-D-R-S-F-H-K-A-I-H-G-T-M-A-A-L-I-K-N-M-I-K-G-V-T-E-G-F-T-E-I-L-E-I-H-G-L-G-Y-R-A-Q-L-K-G-N-V-L-E-L-H-L-G-K-S-H-P-D-I-Y-P-I-P-P-D-V-K-I-E-V-K-G-N-E-I-H-I-H-G-I-D-K-Q-R-V-G-Q-V-A-A-E-I-R-S-F-R-K-P-D-P-Y-K-G-K-G-I-R-Y-K-G-E-Q-L-S-S-N-P-E-R-L-Q-V-R-S-K-E-V-R"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-A-V-D-P-I-A-D-M-F-S-A-I-K-N-A-I-M-R-R-D-A-F-L-Y-V-P-S-S-K-M-K-E-R-I-L-E-V-L-K-R-E-G-F-I-Q-D-W-E-A-L-K-G-E-K-Y-E-E-E-F-K-K-M-K-E-L-A-E-K-S-P-N-P-K-M-R-R-Y-L-Q-Q-L-I-D-Y-N-K-G-T-Q-Y-P-L-K-I-Y-L-K-Y-L-D-P-K-K-R-R-S-A-L-T-N-I-V-R-V-S-K-G-G-R-R-V-Y-A-G-V-R-T-M-P-Y-V-K-R-G-L-G-I-A-I-V-S-T-D-A-G-V-M-T-D-H-E-A-R-K-L-R-K-G-G-E-V-I-A-F-V-W"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-A-T-E-T-K-Y-V-P-R-L-Y-K-K-Y-K-E-E-V-V-P-K-L-I-Q-K-F-Q-Y-K-N-P-M-Q-V-P-R-L-V-K-I-V-V-N-M-G-V-G-E-A-V-Q-D-I-K-Q-L-E-R-A-V-E-D-L-R-A-I-T-G-Q-Q-P-M-I-T-R-A-R-K-S-K-A-G-F-K-L-R-K-G-M-P-I-G-C-K-V-T-L-R-N-H-T-M-W-D-F-L-D-K-V-I-S-V-A-L-P-R-V-K-D-F-K-G-L-N-P-R-S-F-D-G-R-G-N-Y-A-F-G-I-A-E-Q-I-V-F-P-E-I-D-Y-D-K-V-D-R-I-R-G-M-D-I-I-I-N-T-T-A-V-S-D-Q-E-S-L-L-A-T-L-T-L-G-L-P-I-R-A-M"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-K-K-G-D-T-V-V-V-V-R-G-K-E-K-G-K-Q-G-K-V-L-K-V-Y-K-R-V-K-R-R-N-K-K-G-E-P-V-S-L-A-P-F-V-I-V-E-G-V-R-L-I-K-K-H-V-K-P-I-E-G-V-R-E-G-G-I-I-E-T-E-G-P-I-D-I-S-N-V-M-L-L-C-P-N-C-N-K-P-T-R-V-G-F-R-I-V-E-E-G-N-V-R-R-K-Y-R-Y-C-K-K-C-N-E-N-I-D-L-V-S-E-K-V-I-K-G-G"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-R-Q-T-Y-L-N-V-A-D-N-S-G-A-K-K-V-Q-V-I-G-I-P-Y-A-P-R-K-Y-A-T-L-R-D-V-V-T-V-T-V-K-E-A-L-P-Q-G-N-A-K-K-G-K-I-Y-R-A-I-I-V-R-T-A-K-E-V-R-R-P-D-G-S-Y-I-K-F-D-D-N-A-C-V-L-L-N-Q-Y-G-E-P-L-G-T-R-V-L-G-P-I-A-R-E-V-R-N-K-G-F-T-K-I-A-S-L-A-P-E-V-V"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-E-K-A-E-K-G-N-P-K-G-K-A-F-R-G-N-K-L-A-F-G-E-Y-G-I-Q-A-L-D-R-A-W-I-T-Q-Q-Q-I-E-A-V-R-V-A-L-V-R-S"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-G-Q-L-K-I-K-D-K-S-Q-R-E-G-Y-K-P-N-Q-A-I-A-I-L-R-Y-A-H-I-S-P-L-K-A-R-L-V-L-R-E-I-H-G-K-D-V-G-E-A-L-Y-L-L-K-V-I-P-K-R-A-A-R-I-A-E-K-L-L-K-S-A-I-A-N-A-E-Q-K-G-L-D-L-D-R-L-Y-I-K-K-A-V-A-D-R-G-P-I-L-K-K-W-I-P-R-A-H-G-R-A-T-M-V-R-K-R-L-S-H-I-T-I-V-L-E-E-K-P-E-G-K-E-E-E"} +{"text": "### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-Q-R-K-P-W-E-I-L-I-R-P-I-I-T-E-K-S-N-R-L-M-E-D-Y-N-K-Y-T-F-E-V-A-L-D-A-S-K-P-E-I-K-E-A-V-E-K-L-F-N-V-K-V-K-K-V-N-T-M-I-V-K-P-K-K-K-R-V-W-E-R-F-R-Q-Y-G-T-T-K-K-W-K-K-A-I-V-T-L-E-K-G-I-N-R-H-P-W-V-C-S-E-V-R-C-R-D-G-C"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA It is important during the early stages of 50S assembly It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-K-I-G-D-V-E-V-R-D-D-V-F-N-V-K-V-K-K-H-V-L-W-E-V-V-K-W-Q-L-A-K-R-R-Q-G-T-H-S-T-K-T-R-G-E-V-A-Y-S-G-R-K-I-L-P-Q-K-G-T-G-N-A-R-H-G-E-R-G-V-N-I-F-V-G-G-G-V-A-H-G-P-K-P-R-D-Y-E-Y-P-L-P-K-K-V-R-K-L-G-L-K-M-A-L-S-D-K-A-Q-N-D-A-I-M-F-V-D-N-I-D-L-G-E-Q-P-K-T-K-K-A-V-E-F-L-K-N-L-G-V-D-K-E-T-L-L-I-V-I-P-E-K-N-E-V-L-Y-K-S-F-R-N-L-Q-N-V-R-V-L-L-P-E-G-L-N-V-Y-D-V-L-W-A-N-K-L-V-I-H-K-E-C-L-D-R-I-Y-K-K-V-E-A"} +{"text": "### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-E-Q-E-K-I-R-I-K-L-K-A-F-D-H-R-V-L-D-Q-S-V-K-Q-I-I-E-T-V-K-R-T-G-G-V-V-R-G-P-I-P-L-P-T-R-K-R-K-W-C-V-L-R-S-P-H-K-F-D-Q-S-R-E-H-F-E-I-R-A-F-S-R-I-I-D-I-T-R-F-T-P-Q-T-I-E-A-L-M-E-I-N-L-P-A-G-V-D-V-E-V-K-M-R-G"} +{"text": "### FUNCTION May be involved in the biosynthesis of molybdopterin ### SEQUENCE -M-T-K-N-E-H-V-N-V-K-L-D-R-D-I-Q-C-A-V-L-T-V-S-D-T-R-T-P-E-T-D-K-G-G-N-L-A-K-E-L-L-S-E-I-N-V-E-I-K-P-E-H-Y-A-I-V-K-D-D-K-Q-A-I-T-E-Q-L-Q-Q-W-L-A-E-D-V-D-V-I-I-T-T-G-G-T-G-I-A-Q-R-D-V-T-I-E-A-V-T-P-L-L-S-K-E-I-E-G-F-G-E-L-F-R-Y-L-S-Y-A-E-D-V-G-T-R-A-L-L-S-R-A-V-A-G-T-V-G-E-Q-L-I-F-S-V-P-G-S-T-G-A-V-K-L-A-M-N-K-L-I-K-P-E-L-N-H-L-I-H-E-L-T-K"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-Q-M-T-V-Q-I-V-T-P-D-G-L-I-Y-D-H-H-A-A-F-V-S-V-K-T-I-D-G-E-L-G-I-L-P-R-H-I-N-T-I-A-V-L-E-V-D-Q-V-K-V-R-R-V-D-D-D-K-H-I-D-W-I-A-V-N-G-G-I-I-E-I-A-D-N-V-I-T-I-V-A-D-S-A-E-R-A-R-D-I-D-I-S-R-A-E-R-A-K-R-R-A-E-L-E-I-E-E-A-H-D-K-H-L-I-D-Q-E-R-R-A-K-I-A-L-Q-R-A-I-N-R-I-N-V-G-T-R-I"} +{"text": "### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-G-Q-T-K-E-I-I-T-T-L-L-P-L-L-V-L-F-L-I-F-Y-F-L-I-V-R-P-Q-R-Q-Q-Q-K-K-H-K-E-M-I-E-G-L-T-K-G-D-K-I-V-T-Q-G-G-L-I-V-E-V-L-K-A-E-A-N-F-F-S-V-K-L-N-D-D-T-T-A-K-L-S-K-N-Y-V-A-F-K-L-D-E-E-T-T-P-N-N-N"} +{"text": "### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-L-L-V-G-L-G-N-P-T-L-R-Y-D-H-T-R-H-N-A-G-F-D-I-L-D-S-L-V-S-E-L-D-L-S-F-I-F-S-P-K-H-N-A-Y-L-C-V-Y-K-D-F-I-L-L-K-P-Q-T-Y-M-N-L-S-G-E-S-V-L-S-A-K-N-F-Y-K-T-K-E-L-L-I-V-H-D-D-L-D-L-P-L-G-V-V-K-F-K-K-G-G-G-N-G-G-H-N-G-L-K-S-I-D-A-L-C-S-N-S-Y-Y-R-L-R-V-G-I-S-K-G-I-N-I-T-E-H-V-L-S-K-F-H-N-N-E-E-P-L-K-N-A-A-F-E-H-A-K-N-A-L-K-F-F-I-E-S-H-D-F-N-A-T-Q-N-R-F-T-L-K-K-P-L-Q-I-E-S"} +{"text": "### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-L-E-G-V-I-R-E-S-I-T-K-A-N-A-K-A-L-K-K-D-G-Y-L-I-A-N-I-Y-G-K-G-V-E-N-V-N-C-A-F-K-L-N-P-F-I-K-Y-L-K-E-K-K-H-L-I-F-P-V-K-L-G-D-K-T-F-E-V-V-V-Q-E-Y-Q-K-N-P-V-T-N-E-L-I-H-V-D-L-L-A-V-T-K-G-V-K-S-K-F-K-V-P-V-K-H-Q-G-T-P-V-G-L-K-N-K-G-I-L-M-L-S-K-K-R-I-S-V-E-C-A-P-E-H-L-P-D-H-Y-L-V-D-V-A-P-L-D-V-N-E-S-I-L-V-R-D-L-E-K-H-E-N-V-K-I-L-D-H-D-S-I-A-V-I-G-V-I-K-A-K"} +{"text": "### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-Q-D-E-L-F-E-T-E-K-A-P-Q-K-N-A-K-N-A-K-N-A-P-K-K-S-F-E-E-H-V-H-S-L-E-R-V-I-D-R-L-N-D-P-N-L-S-L-K-D-G-M-D-L-Y-K-T-A-M-Q-E-L-F-L-A-Q-K-L-L-E-N-A-Y-S-E-Y-E-K-L-Q-T-P-N-K-K-A"} +{"text": "### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-K-L-V-L-G-I-S-G-A-S-G-I-P-L-A-L-R-F-L-E-K-L-P-K-E-I-E-I-F-V-V-A-S-K-N-A-H-V-V-A-L-E-E-S-N-I-N-L-K-N-A-M-K-D-L-R-P-S-A-T-F-F-N-E-Q-D-I-H-A-S-I-A-S-G-S-Y-G-I-H-K-M-A-I-I-P-A-S-M-D-M-V-A-K-I-A-H-G-F-G-G-D-L-I-S-R-S-A-S-V-M-L-K-E-K-R-P-L-L-I-A-P-R-E-M-P-L-S-A-I-M-L-E-N-L-L-K-L-A-H-S-N-A-I-I-A-P-P-M-M-T-Y-Y-T-Q-S-K-T-L-E-A-M-Q-D-F-L-V-G-K-W-F-D-S-L-G-I-E-N-D-L-Y-P-R-W-G-M-N"} +{"text": "### FUNCTION Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis ### SEQUENCE -M-Y-V-V-L-E-G-V-D-G-A-G-K-S-T-Q-V-G-L-L-K-D-R-F-K-N-A-L-F-T-K-E-P-G-G-T-R-M-G-E-S-L-R-R-I-A-L-N-E-N-I-S-E-L-A-R-A-F-L-F-L-S-D-R-A-E-H-I-E-S-V-I-K-P-A-L-K-E-K-K-L-I-I-S-D-R-S-L-I-S-G-M-A-Y-S-Q-F-S-S-L-E-L-N-L-L-A-T-Q-S-V-L-P-E-K-I-I-L-L-L-I-N-K-E-N-L-K-Q-R-L-S-L-K-S-L-D-K-I-E-N-Q-G-I-E-K-L-L-T-I-Q-Q-K-L-K-T-H-A-Y-A-L-Q-E-K-F-G-C-E-V-L-E-L-D-A-Q-K-S-A-K-N-L-H-E-K-I-A-T-F-I-E-C-V-V"} +{"text": "### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-P-D-E-L-R-A-E-K-S-F-P-S-K-P-Y-D-S-L-K-N-K-S-E-F-D-R-V-Y-R-K-G-F-K-K-H-N-P-F-F-S-L-F-V-L-D-L-S-K-E-P-P-K-E-K-E-G-F-K-D-P-L-S-C-R-L-K-D-R-N-T-L-C-L-L-G-L-S-V-S-K-K-V-G-N-A-V-K-R-N-L-I-K-R-R-L-R-S-L-V-T-R-H-A-A-L-C-Q-G-F-A-L-V-F-V-P-R-S-D-C-Y-H-L-D-F-W-A-L-E-K-H-F-L-E-M-L-T-S-I-K-D-Y-M-N-K-A-L-K-D-L-K-K-G-M-T-H-T-H-A-K-Q"} +{"text": "### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-L-I-A-S-N-K-K-A-Y-F-D-Y-E-I-L-E-T-L-E-A-G-L-A-L-L-G-S-E-V-K-A-L-R-Q-T-R-V-N-L-K-D-N-F-V-K-I-I-K-G-E-A-F-L-F-G-V-H-I-S-Y-L-D-T-I-H-A-Y-Y-K-P-N-E-R-R-E-R-K-L-L-L-H-K-K-Q-L-L-K-W-Q-M-E-A-S-K-E-R-L-S-I-V-G-L-K-L-Y-F-N-Q-K-N-R-A-K-I-Q-I-A-L-V-K-G-K-R-L-H-D-K-R-Q-S-L-K-E-K-A-L-N-K-E-I-L-A-D-L-K-H-H-F-K-G"} +{"text": "### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-I-L-S-R-K-V-N-E-G-I-V-I-D-D-N-I-H-I-K-V-I-S-I-D-R-G-S-V-R-L-G-F-E-A-P-E-S-T-L-I-L-R-T-E-L-K-E-A-I-V-S-E-N-Q-K-A-S-A-S-V-D-E-S-L-L-E-N-I-K-K-V-I-K-P"} +{"text": "### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-K-P-I-K-T-Y-D-I-K-E-E-E-L-A-K-T-A-Y-A-T-I-K-T-N-K-G-N-I-T-L-E-L-F-Y-K-D-A-P-Q-A-V-S-N-F-V-T-L-A-K-E-G-F-Y-N-G-L-N-F-H-R-V-I-A-G-F-V-A-Q-G-G-C-P-Y-G-T-G-T-G-G-P-E-H-R-I-K-C-E-V-A-H-N-P-N-K-H-Q-R-G-S-I-S-M-A-H-A-G-R-D-T-G-G-S-Q-F-F-L-C-F-V-D-L-P-H-L-D-G-E-H-T-V-F-G-K-I-T-S-A-E-S-L-S-V-L-D-K-I-K-Q-G-D-I-I-E-S-V-V-F-S-P-S-L"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-I-F-D-V-K-A-P-I-L-G-F-E-T-I-H-K-M-H-L-Q-K-I-D-E-I-F-L-R-L-N-S-A-E-D-N-S-V-V-S-F-T-L-V-N-P-F-A-L-R-K-Y-E-F-E-V-P-T-P-L-K-I-L-L-E-L-E-G-A-K-S-V-L-V-A-N-I-M-V-V-Q-T-P-I-E-L-S-T-V-N-Y-L-A-P-L-I-F-N-L-D-K-Q-L-M-G-Q-V-V-L-D-S-K-K-Y-P-H-Y-H-L-R-E-N-I-L-S-H-T-H-E"} +{"text": "### FUNCTION Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates ### SEQUENCE -M-K-S-I-R-R-G-D-G-L-N-V-V-P-F-I-D-I-M-L-V-L-L-A-I-V-L-S-I-S-T-F-I-A-Q-G-K-I-K-V-S-L-P-N-A-K-N-A-E-K-S-Q-P-N-D-Q-K-V-V-V-I-S-V-D-E-H-D-N-I-F-V-D-D-K-P-T-N-L-E-A-L-S-A-V-V-K-Q-T-D-P-K-T-L-I-D-L-K-S-D-K-S-S-R-F-E-T-F-I-S-I-M-D-I-L-K-E-H-N-H-E-N-F-S-I-S-T-Q-A-Q"} +{"text": "### FUNCTION Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates Protects ExbD from proteolytic degradation and functionally stabilizes TonB ### SEQUENCE -M-G-G-F-S-M-A-M-L-K-D-Y-V-D-V-F-V-F-A-V-L-G-V-A-S-F-L-A-L-W-F-V-I-E-R-V-I-F-Y-S-K-V-D-L-K-A-Y-D-D-I-D-A-L-N-L-D-L-T-K-N-L-T-I-L-Y-V-I-F-S-N-A-P-Y-V-G-L-L-G-T-V-L-G-I-M-V-I-F-Y-D-M-G-V-S-G-G-M-D-A-K-T-I-M-V-G-L-S-L-A-L-K-A-T-A-L-G-L-A-V-A-I-P-T-L-I-A-Y-N-S-L-L-R-K-S-D-V-L-S-E-K-F-R-I-M-K-T"} +{"text": "### FUNCTION Transcriptional regulator ### SEQUENCE -M-D-T-P-N-K-D-D-S-I-I-R-F-S-V-S-L-Q-Q-N-L-L-D-E-L-D-N-R-I-I-K-N-G-Y-S-S-R-S-E-L-V-R-D-M-I-R-E-K-L-V-E-D-N-W-V-E-D-N-P-N-D-G-S-K-I-A-V-L-V-V-I-Y-D-H-H-Q-R-E-L-N-Q-R-M-I-D-I-Q-H-A-S-G-T-H-V-L-C-T-T-H-I-H-M-D-E-H-N-C-L-E-T-I-I-L-Q-G-N-S-L-E-I-Q-R-L-Q-L-E-I-G-G-L-R-G-V-K-F-A-K-L-T-K-A-S-S-F-E-Y-N-E"} +{"text": "### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-N-T-M-N-S-V-L-E-C-K-E-L-A-L-Y-G-G-S-F-D-P-L-H-K-A-H-L-A-I-I-E-Q-T-L-E-L-L-P-F-V-Q-L-I-V-L-P-A-Y-Q-N-P-F-K-K-P-C-F-L-D-A-K-T-R-F-K-E-L-E-R-A-L-K-G-M-P-R-V-L-L-S-D-F-E-I-K-Q-E-R-A-V-P-T-I-E-S-V-L-H-F-Q-K-L-Y-R-P-K-T-L-Y-L-V-I-G-A-D-C-L-R-H-L-S-S-W-T-N-A-K-E-L-L-K-R-V-E-L-V-V-F-E-R-I-G-Y-E-E-I-Q-F-K-G-R-Y-H-P-L-K-G-I-D-A-P-I-S-S-S-A-I-R-A-S-L-G-V"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-E-F-L-V-Q-K-I-G-M-S-R-T-I-D-A-N-S-T-P-V-T-L-L-K-V-L-Q-A-K-V-C-Q-L-E-N-G-K-A-L-V-A-Y-A-M-H-K-K-Y-N-K-A-I-E-G-Q-Q-K-K-Y-Q-L-S-K-E-F-N-H-F-A-T-L-K-A-S-Q-Q-K-E-L-G-D-L-D-L-S-A-L-E-T-L-K-R-V-K-A-S-F-K-T-K-G-R-G-F-A-G-V-M-K-R-W-N-F-Q-G-G-P-A-A-H-G-S-R-F-H-R-R-P-G-S-I-G-N-R-E-W-P-G-R-V-Q-K-G-R-K-M-A-G-H-Y-G-N-E-L-V-T-C-Q-N-E-V-L-S-F-D-K-E-S-M-V-L-V-L-K-G-S-V-A-G-F-S-G-A-Y-G-R-I-R-A-V"} +{"text": "### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-I-K-K-G-P-F-I-D-D-H-L-M-K-K-T-L-K-A-K-E-G-K-D-N-R-P-I-K-T-W-S-R-R-S-T-I-L-P-E-M-I-G-F-T-Y-N-V-H-N-G-R-V-F-V-P-V-Y-I-T-E-N-H-V-G-Y-K-L-G-E-F-A-P-T-R-T-F-K-G-H-K-G-S-V-Q-K-K-I-G-K"} +{"text": "### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-K-A-L-L-K-F-V-R-L-S-P-T-K-A-R-L-I-A-R-Q-I-Q-G-M-N-A-E-L-A-I-A-S-L-E-F-T-P-N-K-A-A-R-V-L-S-K-V-V-A-S-A-V-A-N-G-S-L-D-A-K-S-A-L-I-V-S-C-R-V-D-A-G-P-V-L-R-R-S-I-P-R-A-K-G-R-A-T-A-I-R-K-P-T-S-H-V-F-V-E-V-A-E-G-K-E-M-K-S-S-K-S-H-K-K-N-Q-A-E-G-K"} +{"text": "### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-Y-R-K-Q-M-K-G-R-N-R-G-K-A-H-R-G-N-S-I-A-F-G-D-I-A-I-K-A-I-E-H-G-R-I-D-S-R-Q-I-E-S-A-R-V-A-M-T-R-H-I-K-R-A-G-K-V-W-I-R-V-F-P-D-K-P-L-T-A-K-P-L-E-T-R-M-G-K-G-K-G-S-V-E-K-W-V-M-N-I-K-P-G-R-I-V-Y-E-M-L-G-I-E-E-G-L-A-R-E-A-L-A-L-S-Q-S-K-L-P-F-K-T-K-I-V-T-C-E-S-E-N-E-I-Y"} +{"text": "### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-S-F-T-R-L-N-V-A-D-N-S-G-A-K-E-I-M-C-I-K-V-L-G-G-S-H-K-R-Y-A-S-V-G-S-V-I-V-A-S-V-K-K-A-I-P-N-G-K-V-K-F-G-L-V-V-K-T-V-V-V-R-T-K-K-E-I-Q-R-K-N-G-S-L-V-R-F-D-D-N-A-A-V-I-L-D-A-K-K-D-P-V-G-T-R-I-F-G-P-V-S-R-E-V-R-Y-A-N-F-M-K-I-I-S-L-A-P-E-V-V"} +{"text": "### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-S-E-I-K-K-N-D-M-V-K-V-I-A-G-D-D-K-G-K-V-A-K-V-L-A-V-L-P-K-T-S-Q-V-V-V-E-G-C-K-V-V-K-K-A-I-K-P-T-D-D-N-P-K-G-G-F-I-K-K-E-K-P-M-H-I-S-N-V-K-K-A"} +{"text": "### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-F-G-L-K-Q-F-Y-Q-N-E-V-R-A-K-L-A-Q-E-L-D-I-K-N-P-M-L-L-P-K-L-E-K-I-V-I-S-V-G-A-G-A-H-A-K-D-M-K-I-M-Q-N-I-A-Q-T-I-S-L-V-A-G-Q-K-A-V-I-T-K-A-K-K-S-V-A-G-F-K-I-R-E-G-M-A-V-G-A-K-V-T-L-R-N-K-R-M-Y-N-F-L-E-K-L-I-V-I-S-L-P-R-V-K-D-F-R-G-I-S-R-N-G-F-D-G-R-G-N-Y-T-F-G-I-N-E-Q-L-I-F-P-E-V-V-Y-D-D-I-M-V-S-H-G-M-N-I-T-M-V-T-S-T-D-N-D-K-E-A-F-K-L-L-E-L-L-G-L-P-F-A-K-V-R"} +{"text": "### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-A-Q-R-K-P-K-F-Q-V-R-A-Y-T-R-C-R-I-C-G-R-P-H-S-V-Y-R-D-F-G-L-C-R-V-C-L-R-K-M-A-S-E-G-L-I-P-G-L-R-K-A-S-W"} +{"text": "### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-R-I-I-E-I-P-S-S-V-Q-A-S-V-E-G-S-K-L-L-F-K-N-N-K-E-K-H-E-L-E-T-H-N-R-V-K-I-T-L-E-N-N-Q-L-S-F-Q-P-V-G-E-D-A-Q-F-R-A-Y-W-G-T-Y-G-A-L-A-N-N-I-V-I-G-L-S-A-G-F-S-K-T-L-E-V-N-G-V-G-Y-K-V-A-L-G-H-K-T-L-D-L-S-L-G-F-S-H-P-V-K-Y-P-I-P-A-G-I-E-M-V-V-E-K-N-T-I-T-I-K-G-S-D-K-Q-Q-V-G-Q-V-A-A-E-I-R-S-F-R-P-P-E-P-Y-K-G-K-G-V-K-Y-S-N-E-V-I-I-R-K-A-G-K-T-A-K-K"} +{"text": "### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-N-A-K-A-L-Y-K-K-K-A-L-R-D-R-R-K-L-R-I-K-S-K-L-L-G-D-K-L-R-P-R-V-S-V-F-R-S-N-R-Y-F-Y-A-Q-A-I-D-D-V-K-Q-S-T-I-T-H-I-D-G-R-K-M-G-F-K-N-T-Q-E-D-A-K-K-L-G-A-L-F-A-E-E-L-K-K-A-G-I-E-R-A-V-Y-D-R-N-G-Y-L-Y-H-G-V-V-A-A-F-A-E-S-L-R-E-N-G-I-V-L"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-G-L-E-N-L-K-P-A-K-G-S-V-K-K-I-K-R-V-G-R-G-Q-G-S-G-M-G-K-T-A-T-R-G-G-K-G-Q-T-A-R-T-G-Y-K-A-K-R-G-F-E-G-G-Q-Q-P-L-Q-R-R-L-P-K-I-G-F-R-T-K-D-S-H-I-Y-S-I-N-V-E-K-N-E-A-I-K-S-L-E-E-I-T-F-S-S-L-R-A-L-H-H-F-P-L-Y-I-E-G-V-K-L-I-G-K-D-A-K-N-L-A-S-K-I-K-D-E-R-I-K-T-S-G-Q-K"} +{"text": "### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-L-P-K-K-K-R-V-E-Y-A-L-T-C-K-N-G-I-G-L-K-S-S-R-E-I-L-E-A-V-G-I-S-F-D-K-R-V-H-E-L-S-E-D-E-V-S-S-I-A-K-K-I-Q-Q-S-Y-L-V-E-G-D-L-R-K-K-V-Q-M-D-I-K-S-L-M-D-L-G-N-Y-R-G-I-R-H-R-K-G-L-P-V-R-G-Q-T-T-K-N-N-A-R-T-R-K-G-K-K-K-T-V-G-S-K"} +{"text": "### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-R-N-V-T-A-K-K-K-V-V-K-K-N-I-A-R-G-V-V-Y-I-S-A-T-F-N-N-T-N-I-T-I-T-D-E-M-G-N-V-I-C-W-S-T-A-G-G-L-G-F-K-G-S-K-K-S-T-P-Y-A-A-Q-Q-A-V-E-S-A-L-S-K-A-K-E-H-G-V-K-E-V-G-I-K-V-Q-G-P-G-S-G-R-E-T-A-I-K-S-V-G-A-T-E-G-V-K-V-L-W-I-K-D-I-T-P-L-P-H-N-G-C-R-P-P-K-R-R-R-V"} +{"text": "### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-Q-A-I-Y-N-E-T-K-D-L-M-Q-K-S-I-Q-A-L-N-R-D-F-S-T-L-R-S-A-K-V-S-V-N-I-L-D-H-I-K-V-D-Y-Y-G-T-P-T-A-L-N-Q-V-G-S-V-M-S-L-D-A-T-T-L-Q-I-S-P-W-E-K-N-L-L-K-E-I-E-R-S-I-Q-E-A-N-I-G-V-N-P-N-N-D-G-E-T-I-K-L-F-F-P-P-M-T-T-E-Q-R-K-L-I-A-K-D-A-K-A-M-G-E-K-A-K-V-A-V-R-N-T-R-Q-D-A-N-N-K-V-K-K-L-E-K-D-K-E-I-S-E-D-E-S-K-K-A-Q-E-Q-I-Q-K-I-T-D-E-A-I-K-K-I-D-E-S-V-K-N-K-E-D-A-I-L-K-V"} +{"text": "### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-T-S-A-L-L-G-L-Q-I-V-L-A-V-L-I-V-V-V-V-L-L-Q-K-S-S-S-I-G-L-G-A-Y-S-G-S-N-D-S-L-F-G-A-K-G-P-A-S-F-M-A-K-L-T-M-F-L-G-L-L-F-V-I-N-T-I-A-L-G-Y-F-Y-N-K-E-Y-G-K-S-V-L-D-E-T-K-T-N-K-E-L-S-P-L-V-P-A-T-G-T-L-N-P-T-L-N-P-T-L-N-P-T-L-N-P-L-E-Q-A-P-T-N-P-L-M-P-T-Q-T-P-K-E-L-P-K-E-P-A-K-T-P-F-V-E-S-P-K-Q-N-E-K-N-E-K-N-D-A-K-E-N-G-I-K-G-V-E-K-N-K-E-N-A-K-T-P-P-T-T-H-Q-K-P-K-T-H-A-T-T-N-A-H-T-N-Q-K-K-D-E-K"} +{"text": "### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-T-M-F-I-L-K-P-T-L-V-E-E-E-I-K-S-K-I-E-F-Y-R-E-V-I-T-K-H-H-G-V-I-E-T-S-L-D-M-G-M-R-N-L-A-Y-E-I-K-K-H-K-R-G-Y-Y-Y-V-A-Y-F-K-A-D-P-S-M-I-L-E-L-E-R-L-Y-R-I-N-E-D-V-L-R-F-I-V-I-K-Y-E-S-K-K-E-V-E-A-W-H-A-L-V-D-R-A-N-K-K-P-S-H-A-K-E-K-H-E-K-T-E-H-T-H-S-H-H-A-E-E-A-K-S-T-E-S-H-S-E"} +{"text": "### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-F-N-K-V-I-M-V-G-R-L-T-R-N-V-E-L-K-Y-L-P-S-G-S-A-A-A-T-I-G-L-A-T-S-R-R-F-K-K-Q-D-G-T-L-G-E-E-V-C-F-I-D-A-R-L-F-G-R-T-A-E-I-A-N-Q-Y-L-S-K-G-S-S-V-L-I-E-G-R-L-T-Y-E-S-W-M-D-Q-T-G-K-K-N-S-R-H-T-I-T-A-D-S-L-Q-F-M-D-K-K-S-D-N-P-Q-A-N-S-M-Q-D-S-M-T-H-E-N-F-N-N-A-Y-P-T-N-Y-N-A-P-S-Q-D-P-F-S-Q-A-Q-S-Y-P-Q-N-A-Y-T-K-E-N-S-Q-A-Q-P-S-K-Y-Q-N-S-V-P-E-I-N-I-D-E-E-E-I-P-F"} +{"text": "### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-E-L-I-L-G-S-Q-S-S-A-R-A-N-L-L-K-E-H-G-I-K-F-E-Q-K-A-L-Y-F-D-E-E-S-L-K-T-T-D-P-R-E-F-V-Y-L-A-C-K-G-K-L-E-K-A-K-E-L-L-A-N-N-C-A-I-V-V-A-D-S-V-V-S-V-G-N-R-M-Q-R-K-A-K-N-K-R-E-A-L-E-F-L-K-R-Q-N-G-N-E-I-E-V-L-T-C-S-A-L-I-S-P-V-L-E-W-L-D-L-S-V-F-R-A-R-L-K-A-F-D-C-S-E-I-E-K-Y-L-E-S-G-L-W-Q-G-S-A-G-C-V-R-L-E-D-F-H-K-P-Y-I-K-S-S-S-K-N-L-S-V-G-L-G-L-N-V-E-G-L-L-G-A-L-K-L-G-V-K-L-S-L-L"} +{"text": "### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-L-H-K-K-Y-R-P-N-V-A-A-I-I-M-S-P-D-Y-P-N-T-C-E-V-F-I-A-E-R-I-D-I-E-G-A-W-Q-F-P-Q-G-G-I-D-E-G-E-T-P-L-E-A-L-Y-R-E-L-L-E-E-I-G-T-N-E-I-E-I-L-A-Q-Y-P-R-W-I-A-Y-D-F-P-S-N-M-E-H-K-F-Y-S-F-D-G-Q-K-Q-R-Y-F-L-V-R-L-K-H-V-N-N-I-D-L-N-K-H-T-P-E-F-R-S-Y-Q-F-I-Q-L-K-D-L-L-K-K-I-V-P-F-K-R-Q-V-Y-R-Q-V-I-A-Y-F-R-K-E-G-Y-L-G-C"} +{"text": "### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-L-V-F-L-W-A-A-L-G-G-A-I-G-S-S-L-R-Y-F-V-G-K-M-M-P-S-K-F-L-M-F-E-S-F-P-L-G-T-F-S-V-N-L-I-G-C-F-I-I-G-F-M-G-H-L-A-A-K-K-V-F-G-D-D-F-G-I-F-F-V-T-G-V-L-G-G-F-T-T-F-S-S-Y-G-L-D-T-L-K-L-L-Q-K-S-Q-Y-L-E-A-I-S-Y-V-L-G-T-N-L-L-G-L-I-G-V-A-I-G-W-F-L-A-K-N-F-V-G-V-N"} +{"text": "### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-M-D-W-Y-A-I-Q-T-Y-S-G-S-E-Q-S-V-K-K-A-I-E-N-L-A-N-D-H-D-I-R-D-R-I-Q-E-I-I-V-P-T-E-D-I-I-E-V-S-K-K-S-K-T-K-V-M-E-R-S-L-Y-P-G-Y-V-F-I-K-V-D-L-D-T-V-L-W-H-K-I-Q-S-L-P-R-V-S-R-F-I-G-E-N-K-K-P-T-P-L-S-E-A-D-I-G-H-I-L-E-K-M-N-N-R-A-A-P-K-P-K-I-F-F-E-Q-G-E-V-V-R-V-V-E-G-P-F-A-N-F-T-A-T-V-E-E-Y-D-V-E-H-R-K-L-K-L-N-V-S-I-F-G-R-T-T-P-I-E-I-L-Y-S-Q-V-E-K-I-I"} +{"text": "### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-Q-K-Q-H-Q-R-Q-H-K-V-E-L-V-A-N-L-K-S-Q-F-D-S-A-K-A-L-L-I-C-D-Y-K-G-L-S-V-K-K-L-E-A-L-R-N-K-A-R-I-Q-G-I-K-V-Q-V-I-K-N-T-L-A-H-I-A-M-K-E-V-G-C-A-D-L-D-L-K-E-T-N-V-F-L-W-G-D-D-Q-I-A-L-S-K-L-V-F-D-F-Q-K-E-H-K-D-H-F-V-L-K-A-G-L-F-D-K-E-S-V-S-V-A-H-V-E-A-V-S-K-L-P-S-K-E-E-L-M-G-M-L-L-S-V-W-T-A-P-A-R-Y-F-V-T-G-L-D-N-L-R-K-A-K-E-E-N"} +{"text": "### FUNCTION Low-potential electron donor to a number of redox enzymes ### SEQUENCE -M-G-K-I-G-I-F-F-G-T-D-S-G-N-A-E-A-I-A-E-K-I-S-K-A-I-G-N-A-E-V-I-D-V-A-K-A-S-K-E-Q-F-N-G-F-T-K-V-I-L-V-A-P-T-A-G-A-G-D-L-Q-T-D-W-E-D-F-L-G-T-L-E-A-S-D-F-A-N-K-T-I-G-L-V-G-L-G-D-Q-D-T-Y-S-E-T-F-A-E-G-I-F-H-I-Y-E-K-A-K-A-G-K-V-V-G-Q-T-P-T-D-G-Y-H-F-E-A-S-K-A-V-E-G-G-K-F-V-G-L-V-I-D-E-D-N-Q-D-D-L-T-D-E-R-I-A-K-W-V-E-Q-V-K-G-S-F-A"} +{"text": "### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-L-E-I-D-N-Q-T-P-L-E-S-D-F-L-L-L-E-K-I-A-D-V-L-A-S-T-Q-I-I-E-L-V-L-V-S-D-E-T-M-R-E-I-N-R-D-L-R-D-C-D-Y-A-T-D-V-L-S-F-P-L-E-A-I-P-H-T-P-L-G-S-V-V-I-N-A-P-L-A-Q-E-N-A-L-K-L-G-H-S-L-E-D-E-I-A-L-L-F-I-H-G-V-L-H-L-L-G-Y-D-H-E-K-D-K-G-E-Q-R-Q-K-E-G-E-L-I-K-A-F-D-L-P-L-S-L-I-E-R-T-Q-E-C"} +{"text": "### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-N-Y-F-L-K-A-P-I-L-G-F-E-H-I-N-E-V-R-L-E-K-I-D-S-L-F-S-R-L-M-G-Q-T-N-S-P-M-A-L-D-M-V-L-V-N-P-Y-C-L-R-E-Y-S-F-V-I-P-K-Y-I-E-L-L-L-E-L-D-S-H-S-K-V-E-V-Y-C-V-V-V-L-Q-K-N-L-E-D-S-M-V-N-F-L-A-P-L-V-F-N-S-K-N-G-F-G-A-Q-V-A-L-S-M-M-D-Y-P-D-F-G-F-R-D-P-L-K-S-F-V-V-K-E-R-E-R-A"} +{"text": "### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-L-L-V-G-R-I-G-K-S-V-G-L-N-G-G-L-K-L-H-L-E-S-D-F-P-E-C-L-K-K-G-V-K-V-S-V-A-P-I-N-A-F-S-C-A-S-S-F-K-D-Y-V-I-H-S-Y-E-H-A-K-N-L-L-F-L-E-T-I-R-T-P-E-K-A-K-E-L-T-N-L-G-L-F-M-S-E-A-E-S-K-K-L-C-V-L-K-E-G-E-F-F-Y-C-D-L-I-G-L-S-V-V-E-G-N-E-I-L-G-K-V-I-E-I-Q-R-I-S-Q-T-D-Y-F-M-V-E-T-T-R-S-L-V-E-K-G-L-A-K-I-F-L-I-P-Y-R-D-F-Y-I-Q-E-I-L-L-Q-D-K-K-I-T-T-H-N-A-K-T-L-L-E-N-S"} +{"text": "### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-K-N-R-Y-I-Q-Q-F-E-D-A-Q-L-K-D-K-S-M-P-T-F-K-A-G-D-T-L-R-L-G-I-T-I-K-E-G-E-K-T-R-T-Q-Y-F-E-G-V-C-I-A-I-R-G-N-G-V-D-K-T-F-C-V-R-K-I-G-A-N-N-I-G-V-E-K-I-F-P-F-Y-S-E-S-L-A-S-V-E-V-L-R-V-G-R-V-R-R-A-K-L-Y-Y-L-R-D-R-R-G-K-A-A-R-I-K-E-V-R-H"} +{"text": "### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-F-V-V-K-M-V-L-G-F-L-I-L-L-S-P-L-C-A-T-G-L-D-I-S-Q-T-D-I-I-E-R-S-L-N-F-L-L-F-V-G-I-L-W-Y-F-L-A-K-R-L-R-S-F-L-H-S-K-S-L-E-I-S-K-R-L-E-E-I-Q-A-Q-L-K-V-S-K-E-H-K-K-K-L-L-K-E-L-E-Q-A-K-E-K-A-E-L-I-I-S-D-A-N-K-E-A-Y-T-I-T-Q-K-Y-E-L-Q-T-K-M-D-V-E-N-L-I-K-N-S-K-A-L-M-D-L-E-V-K-K-I-K-R-E-L-V-E-S-V-F-K-D-L-R-E-S-K-K-V-S-F-N-A-Q-D-C-V-N-I-L-K-Q-R-L"} +{"text": "### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-L-L-K-I-S-V-V-V-P-E-G-E-V-Y-T-G-E-V-K-S-V-V-L-P-G-V-E-G-E-F-G-V-L-Y-G-H-S-N-M-I-T-L-L-Q-A-G-V-V-E-I-E-T-E-N-Q-K-E-H-I-A-I-N-W-G-Y-A-E-V-T-N-E-R-V-D-I-L-A-D-G-A-V-F-I-K-K-G-S-D-D-R-D-D-A-I-S-R-A-K-K-L-L-E-D-A-S-S-D-R-L-A-V-S-S-V-L-A-K-I-E-S-L"} +{"text": "### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-Q-I-D-D-A-L-L-Q-R-L-E-K-L-S-M-L-E-I-K-D-E-H-K-E-S-V-K-G-H-L-A-E-V-L-G-F-V-E-N-I-F-A-L-E-T-N-N-L-K-T-D-T-H-L-S-T-P-L-R-E-D-E-P-K-S-Q-P-H-I-A-K-E-I-L-S-Q-N-K-H-S-Q-D-H-Y-F-V-V-P-K-I-I-E"} +{"text": "### FUNCTION Specifically methylates the pseudouridine at position 1915 in 23S rRNA ### SEQUENCE -M-R-C-V-V-Y-S-I-A-K-N-S-P-L-E-L-V-K-S-Y-Q-K-Q-C-K-R-F-D-C-E-L-E-L-V-D-L-F-P-K-N-T-A-N-A-Q-K-V-S-K-E-L-A-Q-K-S-Y-S-L-A-F-E-P-Y-L-S-P-K-A-K-N-I-A-L-H-P-E-A-Q-R-G-D-S-F-A-F-S-K-M-L-E-N-H-L-N-I-N-F-F-I-A-G-A-Y-G-F-E-E-K-F-L-K-D-C-Q-A-W-S-L-S-E-M-T-F-S-H-E-V-A-K-I-V-L-C-E-Q-I-Y-R-A-L-S-I-I-F-K-H-P-Y-H-K"} +{"text": "### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-N-T-Y-K-N-S-L-N-H-F-L-N-L-V-D-C-L-E-K-I-P-N-V-G-K-K-S-A-F-K-M-A-Y-H-L-G-L-E-N-P-Y-L-A-L-K-I-T-H-A-L-R-N-A-L-E-N-L-K-T-C-A-S-C-N-A-L-S-E-T-E-V-S-E-I-C-S-D-E-S-R-Q-N-S-Q-L-C-M-V-L-H-P-R-D-V-F-I-L-E-D-L-K-D-F-L-G-R-Y-Y-V-L-N-S-I-E-D-V-D-F-N-A-L-E-K-R-L-I-G-E-N-I-K-E-I-I-F-A-F-P-P-T-L-A-N-D-S-L-M-L-Y-I-E-D-K-L-Q-H-L-H-L-T-F-T-K-I-A-Q-G-V-P-T-G-V-N-F-E-N-I-D-S-V-S-L-S-R-A-F-N-S-R-I-K-A"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-V-G-L-I-G-V-V-E-K-I-S-A-L-E-A-H-I-E-V-Q-G-V-V-Y-G-V-Q-V-S-M-R-T-A-A-L-L-Q-T-G-Q-K-A-R-L-K-I-L-Q-V-I-K-E-D-A-H-L-L-Y-G-F-L-E-E-S-E-K-I-L-F-E-R-L-L-K-I-N-G-V-G-G-R-I-A-L-A-I-L-S-S-F-S-P-N-E-F-E-N-I-I-A-T-K-E-V-K-R-L-Q-Q-V-P-G-I-G-K-K-L-A-D-K-I-M-V-D-L-I-G-F-F-I-Q-D-E-N-R-P-A-R-N-E-V-F-L-A-L-E-S-L-G-F-K-S-A-E-I-N-P-V-L-K-T-L-K-P-H-L-S-I-E-A-A-I-K-E-A-L-Q-Q-L-R-S"} +{"text": "### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-I-K-I-Q-K-I-H-P-N-A-L-I-P-K-Y-Q-T-E-G-S-S-G-F-D-L-H-A-V-E-E-V-V-I-K-P-H-S-V-G-L-V-R-I-G-I-C-L-S-L-E-V-G-Y-E-L-Q-V-R-T-R-S-G-L-A-L-N-H-Q-V-M-V-L-N-S-P-G-T-V-D-N-D-Y-R-G-E-I-K-V-I-L-A-N-L-S-D-K-D-F-K-V-Q-V-G-D-R-I-A-Q-G-V-V-Q-K-T-Y-K-A-E-F-I-E-C-E-Q-L-D-E-T-S-R-G-S-G-G-F-G-S-T-G-V-S-K-A"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-A-E-F-I-D-L-V-K-K-A-G-K-Y-N-S-K-R-E-A-E-E-A-I-N-A-F-T-L-A-V-E-T-A-L-S-K-G-E-S-V-E-L-V-G-F-G-K-F-E-T-A-E-Q-K-G-K-E-G-K-V-P-G-S-D-K-T-Y-K-T-E-D-K-R-V-P-K-F-K-P-G-K-I-L-K-Q-K-V-E-E-G-K"} +{"text": "### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-G-I-D-I-V-S-I-A-R-I-E-K-C-V-K-R-F-E-M-R-F-L-E-R-F-L-S-P-S-E-I-V-L-C-K-D-K-S-S-S-I-A-G-F-F-A-L-K-E-A-C-S-K-A-L-Q-V-G-I-G-K-E-L-S-F-L-D-M-R-I-S-K-S-P-K-N-A-P-L-I-T-L-S-K-E-K-M-D-Y-F-N-I-Q-S-L-S-A-S-I-S-H-D-A-G-F-A-I-A-V-V-M-V-S-S-S-N-L"} +{"text": "### FUNCTION Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor ### SEQUENCE -M-Q-T-I-H-I-G-V-L-S-A-S-D-R-A-S-K-G-V-Y-E-D-L-S-G-K-A-I-Q-E-V-L-S-E-Y-L-L-N-P-L-E-F-H-Y-E-I-V-A-D-E-R-D-L-I-E-K-S-L-I-K-M-C-D-E-Y-Q-C-D-L-V-V-T-T-G-G-T-G-P-A-L-R-D-I-T-P-E-A-T-K-K-V-C-Q-K-M-L-P-G-F-G-E-L-M-R-M-T-S-L-K-Y-V-P-T-A-I-L-S-R-Q-S-A-G-I-R-N-K-S-L-I-I-N-L-P-G-K-P-K-S-I-R-E-C-L-E-A-V-F-P-A-I-P-Y-C-V-D-L-I-L-G-N-Y-M-Q-V-N-E-K-N-I-Q-A-F-R-P-K-Q"} +{"text": "### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-G-Y-I-P-Y-V-I-E-N-T-E-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-D-R-I-V-L-L-S-G-E-I-N-D-S-V-A-S-S-I-V-A-Q-L-L-F-L-E-A-E-D-P-E-K-D-I-G-L-Y-I-N-S-P-G-G-V-I-T-S-G-L-S-I-Y-D-T-M-N-F-I-R-P-D-V-S-T-I-C-I-G-Q-A-A-S-M-G-A-F-L-L-S-C-G-A-K-G-K-R-F-S-L-P-H-S-R-I-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-S-D-I-E-I-I-S-N-E-I-L-R-L-K-G-L-M-N-S-I-L-A-Q-N-S-G-Q-S-L-E-Q-I-A-K-D-T-D-R-D-F-Y-M-S-A-K-E-A-K-E-Y-G-L-I-D-K-V-L-Q-K-N-V-K"} +{"text": "### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-L-L-E-I-I-H-Y-P-S-K-I-L-R-T-I-S-K-E-V-V-S-F-D-S-K-L-H-Q-Q-L-D-D-M-H-E-T-M-I-A-S-E-G-I-G-L-A-A-I-Q-V-G-L-P-L-R-M-L-I-I-N-L-P-Q-E-D-G-V-Q-H-K-E-D-C-L-E-I-I-N-P-K-W-I-E-T-K-G-S-I-M-Y-R-E-G-C-L-S-V-P-G-F-Y-E-E-V-E-R-F-E-K-V-K-I-E-Y-Q-N-R-F-A-E-V-K-I-L-E-A-S-E-L-L-A-V-A-I-Q-H-E-I-D-H-L-N-G-V-L-F-V-D-K-L-S-I-L-K-R-K-K-F-E-K-E-L-K-E-L-Q-K-K-Q-K-H-K"} +{"text": "### FUNCTION Participates in the translocation of lipoproteins from the inner membrane to the outer membrane Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate ### SEQUENCE -M-K-A-F-L-K-I-C-M-V-L-I-F-V-G-V-A-H-A-K-N-P-L-T-L-S-K-E-E-E-V-L-Q-N-L-Q-S-F-S-A-H-F-K-Q-V-L-K-N-E-K-P-L-V-Y-Y-G-V-L-K-A-K-A-P-N-W-A-L-W-V-Y-E-K-P-L-K-K-E-I-Y-M-N-D-K-E-V-V-V-Y-E-P-N-L-F-Q-A-T-I-T-P-L-K-D-K-T-D-F-F-T-I-L-K-Q-L-K-K-Q-T-D-G-S-F-K-T-T-I-N-K-T-T-Y-R-L-V-F-K-D-G-K-P-F-S-L-E-F-K-D-D-M-N-N-L-V-T-I-T-F-S-Q-A-E-I-N-P-K-I-P-N-E-I-F-V-F-N-P-K-D-E-N-I-D-I-V-R-Q"} +{"text": "### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-N-E-M-L-K-E-E-L-L-Q-S-I-R-E-V-K-D-Y-P-K-K-G-I-L-F-K-D-I-T-T-L-L-N-Y-P-K-L-F-N-K-L-I-D-A-L-K-K-R-Y-L-A-L-N-I-D-F-I-V-G-I-E-A-R-G-F-I-L-G-S-A-F-A-Y-A-L-G-V-G-F-V-P-V-R-K-K-G-K-L-P-A-H-T-L-S-Q-S-Y-S-L-E-Y-G-S-D-S-I-E-I-H-S-D-A-F-R-G-I-K-G-V-R-V-V-L-V-D-D-L-L-A-T-G-G-T-A-L-A-S-L-E-L-I-K-A-L-Q-A-E-C-I-E-A-C-F-L-I-G-L-K-E-L-P-G-I-Q-L-L-E-E-H-V-K-T-F-C-L-L-E-C"} +{"text": "### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-L-F-E-D-I-Q-A-V-I-A-E-Q-L-N-V-D-A-A-Q-V-T-P-E-A-E-F-V-K-D-L-G-A-D-S-L-D-V-V-E-L-I-M-A-L-E-E-K-F-N-I-E-I-P-D-E-Q-A-E-K-I-V-N-V-G-D-V-V-K-Y-I-E-D-N-K-L-A"} +{"text": "### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-L-L-L-E-D-V-K-N-L-G-K-A-G-E-V-C-E-V-K-D-G-Y-G-N-N-F-L-I-A-N-Q-K-A-K-L-A-T-N-E-V-I-N-K-Y-K-A-E-V-K-K-K-A-E-K-E-A-L-E-K-A-Q-K-L-Q-M-V-E-T-L-Q-T-I-T-L-T-I-H-K-K-V-G-A-N-G-S-L-F-G-A-I-T-K-E-E-I-T-E-R-L-K-E-Q-H-A-S-L-N-L-D-K-K-D-I-E-L-K-H-P-I-K-S-T-G-I-Y-E-I-E-V-K-L-G-S-G-I-A-G-V-F-K-I-D-V-V-A-E"} +{"text": "### FUNCTION Thioesterase that may be involved in phospholipid metabolism Displays acyl-CoA thioesterase activity with lauroyl-CoA ### SEQUENCE -M-R-C-R-V-Y-Y-E-D-T-D-S-E-G-V-V-Y-H-A-N-Y-L-K-Y-C-E-R-A-R-S-E-F-F-F-K-Q-N-V-L-P-E-N-E-E-G-V-F-V-I-R-S-I-K-A-D-F-F-T-P-A-S-L-G-Q-V-L-E-I-R-T-Q-I-K-E-L-R-K-V-F-V-V-L-F-Q-E-I-Y-C-I-Q-N-A-S-L-E-P-M-K-P-F-K-V-F-A-S-E-I-K-F-G-F-V-N-R-S-T-Y-S-P-I-A-I-P-K-L-F-K-E-L-L-S-A-V"} +{"text": "### FUNCTION Acts as a global negative controlling element, employing Fe as a cofactor to bind the operator of the repressed genes ### SEQUENCE -M-R-R-L-E-T-L-E-S-I-L-E-R-L-R-M-S-I-K-K-N-G-L-K-N-S-K-Q-R-E-E-V-V-S-V-L-Y-R-S-G-T-H-L-S-P-E-E-I-T-H-S-I-R-Q-K-D-K-N-T-S-I-S-S-V-Y-R-I-L-N-F-L-E-K-E-N-F-I-C-V-L-E-T-S-K-S-G-R-R-Y-E-I-A-A-K-E-H-H-D-H-I-I-C-L-H-C-G-K-I-I-E-F-A-D-P-E-I-E-H-R-Q-N-E-V-V-K-K-Y-Q-A-K-L-I-S-H-D-M-K-M-F-V-W-C-K-E-C-Q-E-S-D-D"} +{"text": "### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-N-L-E-K-K-Q-E-I-I-K-A-F-A-T-K-A-N-D-T-G-S-C-E-V-Q-V-A-L-L-N-E-R-I-K-L-L-T-E-H-L-K-T-N-P-K-D-H-S-S-R-L-G-L-L-K-L-V-A-Q-R-R-N-L-L-K-Y-I-K-R-T-D-H-V-R-Y-V-V-L-I-E-K-L-G-I-K-D-R"} +{"text": "### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-K-K-I-E-E-K-I-E-G-V-I-E-S-L-G-Y-L-L-Y-D-V-S-L-V-K-E-N-E-Q-H-V-L-R-V-S-L-K-N-P-N-G-A-V-S-L-D-I-C-Q-Q-V-S-E-I-I-S-P-L-L-D-V-C-D-F-I-Q-D-A-Y-I-L-E-V-S-S-M-G-L-E-R-T-L-K-T-P-K-H-F-K-L-S-L-G-E-K-V-E-V-K-L-I-N-K-E-S-F-Q-A-V-L-K-D-A-N-D-L-S-A-D-F-E-L-D-N-H-A-I-K-S-V-E-Y-K-D-L-K-K-V-K-T-L-F-E-W"} +{"text": "### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-N-A-H-K-E-R-L-E-S-N-L-L-E-L-L-Q-E-A-L-A-S-L-N-D-S-E-L-N-S-L-S-V-T-K-V-E-C-S-K-G-K-H-H-A-L-V-F-V-L-S-S-D-H-K-I-L-S-K-L-K-K-A-E-G-L-I-R-Q-F-V-L-Q-A-S-G-W-F-K-C-P-K-L-S-F-V-L-D-D-S-L-E-K-Q-L-R-L-D-A-I-F-N-E-I-A-K-G-K-D-N-D"} +{"text": "### FUNCTION Cell division inhibitor that blocks the formation of polar Z ring septums Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings Prevents FtsZ polymerization ### SEQUENCE -M-L-K-T-N-Q-K-N-V-H-A-F-E-I-E-K-Q-E-P-E-A-V-M-E-F-L-E-K-N-H-A-L-L-Q-Y-F-L-I-I-F-K-Y-D-I-E-S-E-V-K-A-V-L-H-K-H-Q-L-L-F-L-E-T-N-R-A-L-N-G-R-Y-I-K-T-T-E-K-D-A-N-L-L-K-Q-N-S-P-N-A-I-E-P-K-T-T-I-Y-E-R-N-I-R-S-G-E-E-I-Y-S-T-N-H-L-I-F-L-G-N-I-H-N-G-A-K-I-I-S-E-G-S-V-S-V-Y-G-V-C-E-G-A-I-V-C-F-G-E-Y-L-I-L-K-E-V-K-S-A-Q-I-V-F-Q-N-K-I-L-S-L-K-E-V-E-R-L-L-V-N-K-N-I-K-I-I-T-K-N-D-D-I-L-D-I-K-E-V-L"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-G-M-G-F-F-E-I-L-V-V-L-I-V-A-I-I-F-L-G-P-E-K-F-P-Q-A-V-V-D-I-V-K-F-F-R-A-V-K-K-T-L-N-D-A-K-D-T-L-D-K-E-I-N-I-E-E-I-K-K-E-T-L-E-Y-Q-K-L-F-E-N-K-V-E-S-L-K-G-V-K-I-E-E-L-E-D-A-K-V-T-A-E-N-E-I-K-S-I-Q-D-L-M-Q-D-Y-K-R-S-L-E-T-N-T-I-P-N-H-L-N-E-E-V-S-N-E-E-A-L-N-K-E-V-S-S-D-E-S-P-K-E-V-Q-L-T-T-D-N-N-A-K-E-H-D-K-E-K-E-H-V"} +{"text": "### FUNCTION Specifically methylates the N7 position of guanine in position 527 of 16S rRNA ### SEQUENCE -M-N-P-L-L-Q-D-Y-A-R-I-L-L-E-W-N-Q-T-H-N-L-S-G-A-R-N-L-S-E-L-E-P-Q-I-T-D-A-L-K-P-L-E-F-V-K-D-F-K-S-C-L-D-I-G-S-G-A-G-L-P-A-I-P-L-A-L-E-K-P-E-A-Q-F-I-L-L-E-P-R-V-K-R-A-A-F-L-N-Y-L-K-S-V-L-P-L-N-N-I-E-I-I-K-K-R-L-E-D-Y-Q-N-L-L-Q-V-D-L-I-T-S-R-A-V-A-S-S-S-F-L-I-E-K-S-Q-R-F-L-K-D-K-G-Y-F-L-F-Y-K-G-E-Q-L-K-N-E-I-A-Y-K-T-T-E-C-F-M-H-Q-K-R-V-Y-F-Y-K-S-K-E-S-L-C"} +{"text": "### FUNCTION Chemotactic response regulator protein that modulates the rotation direction of bacterial flagellar motors Plays an important role in the colonization and infection of Helicobacter pylori Upon phosphorylation by CheA, interacts with the flagellar motor protein FliM to cause clockwise flagellar rotation and bacterial reversals, as opposed to straight swimming when CheY1 is not phosphorylated ### SEQUENCE -M-K-L-L-V-V-D-D-S-S-T-M-R-R-I-I-K-N-T-L-S-R-L-G-Y-E-D-V-L-E-A-E-H-G-V-E-A-W-E-K-L-D-A-N-A-D-T-K-V-L-I-T-D-W-N-M-P-E-M-N-G-L-D-L-V-K-K-V-R-A-D-N-R-F-K-E-I-P-I-I-M-I-T-T-E-G-G-K-A-E-V-I-T-A-L-K-A-G-V-N-N-Y-I-V-K-P-F-T-P-Q-V-L-K-E-K-L-E-V-V-L-G-T-N-D"} +{"text": "### FUNCTION Part of a cation-transporting system which is associated with copper export out of the Hpylori cells ### SEQUENCE -M-K-V-T-F-Q-V-P-S-I-T-C-N-H-C-V-D-K-I-E-K-F-V-G-E-I-E-G-V-S-F-I-D-A-S-V-E-K-K-S-V-V-V-E-F-D-T-P-A-T-Q-D-L-I-K-E-A-L-L-D-A-G-Q-E-V-V"} +{"text": "### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-I-L-A-C-D-V-G-L-K-R-I-G-I-A-A-L-L-N-G-V-I-L-P-L-E-A-I-L-R-H-N-R-N-Q-A-S-R-D-L-S-D-L-L-R-K-K-D-I-Q-V-L-V-V-G-K-P-N-E-S-Y-A-D-T-H-A-R-I-E-H-F-I-K-L-V-D-F-K-G-E-I-V-F-I-N-E-D-N-S-S-V-E-A-Y-E-N-L-E-H-L-G-K-K-N-K-R-I-A-T-K-D-G-R-L-D-S-L-S-A-C-R-I-L-E-R-Y-C-Q-Q-V-L-K-K-G"} +{"text": "### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-F-D-F-F-K-N-K-G-S-A-A-T-A-T-D-R-L-K-L-I-L-A-K-E-R-T-L-N-L-P-Y-M-E-E-M-R-K-E-I-I-A-V-I-Q-K-Y-T-K-S-S-D-I-H-F-K-T-L-D-G-N-Q-S-V-E-T-I-E-V-E-I-I-L-P-K"} +{"text": "### FUNCTION Part of the twin-arginine translocation system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-F-T-S-I-W-H-W-V-I-V-L-L-V-I-V-L-L-F-G-A-K-K-I-P-E-L-A-K-G-L-G-S-G-I-K-N-F-K-K-A-V-K-D-D-E-E-E-A-K-N-E-L-K-T-L-D-A-Q-A-T-Q-T-K-V-H-E-T-S-E-I-K-S-K-Q-E-S"} +{"text": "### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-Y-A-I-F-K-H-G-G-K-Q-Y-K-V-V-E-G-D-I-V-L-L-D-K-M-N-K-E-P-K-A-L-V-E-L-V-E-V-L-A-V-S-K-E-G-K-L-S-C-G-K-P-F-V-N-G-A-K-I-E-A-E-V-I-N-E-G-R-S-K-K-V-I-T-F-K-K-R-R-R-K-D-S-K-T-K-R-G-F-R-R-D-F-T-R-V-R-I-T-K-I-V-A"} +{"text": "### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-I-G-M-S-E-L-K-K-G-L-K-I-E-L-G-G-V-P-Y-R-I-V-E-Y-Q-H-V-K-P-G-K-G-A-A-F-V-R-A-K-I-K-S-F-L-D-G-K-V-I-E-K-T-F-H-A-G-D-K-C-E-E-P-N-L-V-E-K-T-M-Q-Y-L-Y-H-D-G-D-T-Y-Q-F-M-D-I-E-S-Y-E-Q-I-A-L-N-D-S-Q-V-G-E-A-S-K-W-M-L-D-G-M-Q-V-Q-V-L-L-H-N-D-K-A-I-S-V-D-V-P-Q-V-V-A-L-K-I-V-E-T-A-P-N-F-K-G-D-T-S-S-A-S-K-K-P-A-T-L-E-T-G-A-V-V-Q-V-P-F-H-V-L-E-G-E-T-I-K-V-N-T-E-T-E-E-Y-L-E-K-V-K"} +{"text": "### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-R-V-K-T-G-V-V-R-R-R-R-H-K-K-V-L-K-L-A-R-G-F-Y-S-G-R-R-K-H-F-R-K-A-K-E-Q-L-E-R-S-M-Y-Y-A-F-R-D-R-K-Q-K-K-R-E-F-R-S-L-W-V-V-R-I-N-A-A-C-R-M-H-N-T-S-Y-S-R-F-M-H-A-L-K-V-A-N-I-E-L-D-R-K-V-L-A-D-M-A-M-N-D-M-Q-A-F-K-S-V-L-E-S-V-K-E-H-L"} +{"text": "### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-K-D-E-H-N-Q-E-H-D-H-L-S-P-K-E-P-E-S-Y-Q-K-A-Y-A-C-K-E-Q-Q-G-E-E-K-Q-E-A-S-E-K-E-G-E-I-K-E-D-F-E-L-K-Y-Q-E-M-R-E-Q-Y-L-R-V-H-A-D-F-E-N-V-K-K-R-L-E-R-D-K-S-M-A-L-E-Y-A-Y-E-K-I-A-L-D-L-L-P-V-I-D-A-L-L-G-A-H-K-S-A-V-E-V-D-K-E-S-A-L-T-K-G-L-E-L-T-M-E-K-L-H-E-V-L-A-R-H-G-I-E-G-I-E-C-L-E-E-F-D-P-N-F-H-N-A-I-M-Q-V-K-S-E-E-K-E-N-G-K-I-V-Q-V-L-Q-Q-G-Y-K-Y-K-G-R-V-L-R-P-A-M-V-S-I-A-K-N-D"} +{"text": "### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-T-K-T-A-K-V-N-D-I-V-R-D-W-V-V-L-D-A-K-D-K-V-F-G-R-L-I-T-E-I-A-V-L-L-R-G-K-H-R-P-F-Y-T-P-N-V-D-C-G-D-F-V-V-V-I-N-A-N-K-V-K-F-S-G-M-K-L-E-D-K-E-Y-F-T-H-S-G-Y-F-G-S-T-K-S-K-T-L-Q-E-M-L-E-K-T-P-E-K-L-Y-H-L-A-V-R-G-M-L-P-K-T-K-L-G-K-A-M-I-K-K-L-K-V-Y-R-D-D-K-H-P-H-T-A-Q-T-S-K-K-D-A-K"} +{"text": "### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-K-S-A-E-K-R-I-R-Q-T-I-K-R-T-E-R-N-R-F-Y-K-T-K-V-K-N-I-I-K-A-V-R-E-A-V-A-I-N-D-V-A-K-A-Q-E-R-L-K-I-A-N-K-E-L-H-K-F-V-S-K-G-I-L-K-K-N-T-A-S-R-K-V-S-R-L-N-A-S-V-K-K-I-A-L-A"} +{"text": "### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-I-E-R-L-V-G-N-L-R-D-L-N-P-L-D-F-N-V-D-H-V-D-L-E-W-F-E-T-R-K-K-I-A-R-F-K-T-R-Q-G-K-D-I-A-I-R-L-K-D-A-P-K-L-G-L-S-Q-G-D-I-L-F-K-E-E-K-E-I-I-A-V-N-I-L-D-S-E-V-I-H-I-Q-A-K-S-V-A-E-V-A-K-I-C-Y-E-I-G-N-R-H-A-A-L-Y-Y-G-E-S-Q-F-E-F-K-T-P-F-E-K-P-T-L-A-L-L-E-K-L-G-V-Q-N-R-V-L-S-S-K-L-D-S-K-E-R-L-T-V-S-M-P-H-S-E-P-N-F-K-V-S-L-A-S-D-F-K-V-V-V-K"} +{"text": "### FUNCTION Facilitates the functional incorporation of the urease nickel metallocenter This process requires GTP hydrolysis, probably effectuated by UreG ### SEQUENCE -M-V-K-I-G-V-C-G-P-V-G-S-G-K-T-A-L-I-E-A-L-T-R-H-M-S-K-D-Y-D-M-A-V-I-T-N-D-I-Y-T-K-E-D-A-E-F-M-C-K-N-S-V-M-P-R-D-R-I-I-G-V-E-T-G-G-C-P-H-T-A-I-R-E-D-A-S-M-N-L-E-A-V-E-E-M-H-G-R-F-P-N-L-E-L-L-L-I-E-S-G-G-D-N-L-S-A-T-F-N-P-E-L-A-D-F-T-I-F-V-I-D-V-A-E-G-D-K-I-P-R-K-G-G-P-G-I-T-R-S-D-L-L-V-I-N-K-I-D-L-A-P-Y-V-G-A-D-L-K-V-M-E-R-D-S-K-K-M-R-G-E-K-P-F-I-F-T-N-I-R-A-K-E-G-L-D-D-V-I-A-W-I-K-R-N-A-L-L-E-D"} +{"text": "### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-D-F-S-Q-L-G-G-L-S-G-L-L-D-G-V-K-K-E-F-S-Q-L-E-E-K-N-K-D-T-I-H-T-S-K-S-G-G-G-M-V-S-V-S-F-N-G-L-G-E-L-V-D-L-Q-I-D-D-S-L-L-E-D-K-E-A-M-Q-I-Y-L-M-S-A-L-N-D-G-Y-K-A-V-E-E-N-R-K-N-L-A-F-N-M-L-G-N-F-A-K-L"} +{"text": "### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-K-M-H-Q-I-P-T-P-T-M-S-Q-V-I-M-L-N-D-S-I-T-T-A-E-F-M-V-S-A-L-R-D-F-F-D-K-P-L-E-E-A-Q-K-L-M-L-S-I-H-R-D-G-D-G-V-C-G-V-Y-P-Y-E-I-A-I-Y-K-A-V-C-V-R-D-K-A-R-A-R-F-P-L-R-L-M-V-Q-E-V-K"} +{"text": "### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-Q-I-I-E-G-K-L-Q-L-Q-G-N-E-K-I-A-I-L-T-S-R-F-N-H-I-I-T-D-R-L-K-E-G-A-M-D-C-F-K-R-H-G-G-D-E-E-L-L-D-L-V-L-V-P-G-A-Y-E-L-P-L-I-L-D-K-L-L-E-S-G-K-Y-D-G-V-C-V-L-G-A-I-I-R-G-G-T-P-H-F-D-Y-V-S-A-E-A-T-K-G-I-A-S-A-M-L-K-Y-S-M-P-V-S-F-G-V-L-T-T-D-N-I-E-Q-A-I-E-R-A-G-S-K-A-G-N-K-G-F-E-A-M-S-T-L-I-E-L-L-S-L-C-Q-T-L-K-D"} +{"text": "### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA operons ### SEQUENCE -M-A-T-R-T-Q-A-R-G-A-V-V-E-L-L-Y-A-F-E-S-G-N-E-E-I-K-K-I-A-S-S-M-L-E-E-K-K-I-K-N-N-Q-L-A-F-A-L-S-L-F-N-G-V-L-E-K-I-N-E-I-D-A-L-I-E-P-H-L-K-D-W-D-F-K-R-L-G-S-M-E-K-A-I-L-R-L-G-A-Y-E-I-G-F-T-P-T-Q-N-P-I-I-I-N-E-C-I-E-L-G-K-L-Y-A-E-P-N-T-P-K-F-L-N-A-I-L-D-S-L-S-K-K-L-A-Q-K-P-L-I"} +{"text": "### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-K-A-N-N-A-E-T-P-D-S-S-N-A-A-D-T-F-K-W-L-A-A-F-V-L-A-A-A-A-V-V-G-N-Y-L-Y-G-E-M-S-V-V-V-R-A-A-G-V-V-V-L-I-A-A-A-L-G-V-A-A-T-T-T-K-G-K-A-A-I-S-F-A-K-E-S-R-M-E-V-R-K-V-V-W-P-T-R-Q-E-T-M-Q-T-T-L-I-V-L-A-V-S-I-V-M-A-L-V-L-W-G-I-D-G-I-M-V-R-L-V-A-L-A-T-G-V"} +{"text": "### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-E-Y-I-K-G-T-Y-M-G-I-N-K-E-Y-I-V-I-E-N-G-D-I-G-Y-K-I-H-S-S-G-Y-T-I-A-N-M-P-N-I-G-E-H-I-M-L-Y-L-T-Q-I-V-R-E-D-F-I-G-L-Y-G-F-G-S-K-E-E-L-E-L-F-N-K-L-L-T-V-N-G-I-G-A-K-A-S-L-S-L-L-S-I-T-N-V-E-N-L-K-R-A-I-V-L-E-D-E-K-L-L-I-K-A-P-G-I-G-K-K-T-A-Q-R-I-I-L-E-L-K-D-K-L-D-V-N-L-D-E-G-I-Q-T-D-S-N-D-I-K-V-S-S-K-I-L-E-E-A-K-E-A-L-M-S-L-G-Y-S-E-K-E-C-E-K-A-L-K-N-V-E-E-K-E-S-L-E-I-I-I-K-E-S-L-K-F-L-M-N"} +{"text": "### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-A-E-E-H-R-L-Q-E-P-R-L-C-A-N-N-C-G-F-F-G-S-T-A-T-Q-N-L-C-S-K-C-F-R-D-L-Q-H-Q-E-Q-N-S-S-T-A-K-H-A-L-T-Q-S-L-A-A-V-G-A-A-A-S-S-S-V-S-P-P-P-P-P-P-A-D-S-K-E-I-V-E-A-K-S-E-K-R-A-A-A-E-P-E-E-A-D-G-P-P-Q-D-P-K-R-C-L-T-C-R-R-R-V-G-I-T-G-F-R-C-R-C-G-F-V-F-C-G-T-H-R-Y-A-E-Q-H-E-C-S-F-D-F-K-R-M-G-K-D-K-I-A-K-A-N-P-I-V-K-A-D-K-L-E-K-I"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide The M form is known to activate NADP-malate dehydrogenase ### SEQUENCE -M-A-L-E-T-C-L-R-G-W-A-L-Y-A-P-Q-A-G-I-R-E-R-L-S-S-G-S-Y-A-P-S-R-P-R-T-A-A-P-A-V-V-S-P-S-P-Y-K-S-A-L-V-A-A-R-R-P-S-R-F-V-C-K-C-K-N-V-V-D-E-V-I-V-A-D-E-K-N-W-D-N-M-V-I-A-C-E-S-P-V-L-V-E-F-W-A-P-W-C-G-P-C-R-M-I-A-P-V-I-D-E-L-A-K-D-Y-V-G-K-I-K-C-C-K-V-N-T-D-D-C-P-N-I-A-S-T-Y-G-I-R-S-I-P-T-V-L-M-F-K-D-G-E-K-K-E-S-V-I-G-A-V-P-K-T-T-L-C-T-I-I-D-K-Y-I-G-S"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-N-V-L-K-C-L-A-I-I-S-V-L-G-I-F-F-I-P-R-Y-S-E-S-A-I-S-C-S-V-V-L-Q-D-L-Q-P-C-V-S-Y-L-T-S-G-S-G-N-P-P-E-T-C-C-D-G-V-K-S-L-A-A-A-T-T-T-S-A-D-K-K-A-A-C-Q-C-I-K-S-V-A-N-S-V-T-V-K-P-E-L-A-Q-A-L-A-S-N-C-G-A-S-L-P-V-D-A-S-P-T-V-D-C-T-T-V-G"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-S-N-V-S-F-L-E-L-Q-Y-K-L-S-K-N-K-M-L-R-K-P-S-R-M-F-S-R-D-R-Q-S-S-G-L-S-S-P-G-P-G-G-F-S-Q-P-S-V-N-E-M-R-R-V-F-S-R-F-D-L-D-K-D-G-K-I-S-Q-T-E-Y-K-V-V-L-R-A-L-G-Q-E-R-A-I-E-D-V-P-K-I-F-K-A-V-D-L-D-G-D-G-F-I-D-F-R-E-F-I-D-A-Y-K-R-S-G-G-I-R-S-S-D-I-R-N-S-F-W-T-F-D-L-N-G-D-G-K-I-S-A-E-E-V-M-S-V-L-W-K-L-G-E-R-C-S-L-E-D-C-N-R-M-V-R-A-V-D-A-D-G-D-G-L-V-N-M-E-E-F-I-K-M-M-S-S-N-N-V"} +{"text": "### FUNCTION A1b binds to basic 7S globulin and stimulates its phosphorylation activity ### SEQUENCE -M-A-V-F-L-L-A-T-S-T-I-M-F-P-T-K-I-E-A-A-D-C-N-G-A-C-S-P-F-E-V-P-P-C-R-S-S-D-C-R-C-V-P-I-G-L-F-V-G-F-C-I-H-P-T-G-L-S-S-V-A-K-M-V-D-E-H-P-N-L-C-Q-S-D-D-E-C-M-K-K-G-S-G-N-F-C-A-R-Y-P-N-N-Y-I-D-Y-G-W-C-F-D-S-D-S-E-A-L-K-G-F-L-A-M-P-R-A-T-T-K"} +{"text": "### FUNCTION Potential calcium sensor ### SEQUENCE -M-D-S-T-E-L-N-R-V-F-Q-M-F-D-K-D-G-D-G-K-I-T-T-K-E-L-N-E-S-F-K-N-L-G-I-I-I-P-E-D-E-L-T-Q-I-I-Q-K-I-D-V-N-G-D-G-C-V-D-I-E-E-F-G-E-L-Y-K-T-I-M-V-E-D-E-D-E-V-G-E-E-D-M-K-E-A-F-N-V-F-D-R-N-G-D-G-F-I-T-V-D-E-L-K-A-V-L-S-S-L-G-L-K-Q-G-K-T-L-E-E-C-R-K-M-I-M-Q-V-D-V-D-G-D-G-R-V-N-Y-M-E-F-R-Q-M-M-K-K-G-R-F-F-S-S-L-S"} +{"text": "### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-S-L-A-K-A-K-E-I-V-S-G-N-P-V-A-V-F-S-K-T-Y-C-P-F-C-V-S-V-K-D-L-L-S-K-L-G-A-T-F-K-A-V-E-L-D-S-E-K-D-G-S-E-I-Q-A-A-L-A-E-W-T-G-Q-R-T-V-P-N-V-F-I-G-R-K-H-I-G-G-C-D-A-T-T-A-L-H-R-E-G-K-L-L-P-L-L-T-E-A-G-A-I-A-K-T-S-T-A"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-A-K-T-S-S-T-T-K-D-A-Q-D-L-F-H-A-I-W-S-A-Y-S-A-T-P-T-N-L-K-I-I-D-L-Y-V-V-F-A-V-F-T-A-L-L-Q-D-V-Y-M-A-L-V-G-P-F-P-F-N-S-F-L-S-G-V-L-S-C-V-G-T-A-V-L-A-V-C-L-R-I-Q-V-N-K-E-N-K-E-F-K-D-L-G-P-E-R-A-F-A-D-F-V-L-C-N-L-V-L-H-L-V-I-M-N-F-L-G"} +{"text": "### FUNCTION Binds specifically to the 3'-terminal U-tract of U6 snRNA ### SEQUENCE -M-L-P-L-S-L-L-K-T-A-Q-G-H-P-M-L-V-E-L-K-S-G-E-T-Y-N-G-H-L-V-N-C-D-T-W-M-N-I-H-L-R-E-V-I-C-T-S-K-D-G-D-R-F-W-R-M-P-D-C-Y-I-R-G-N-T-I-K-Y-L-R-V-P-D-E-V-I-D-K-V-Q-E-E-T-K-S-R-A-D-R-K-P-P-G-V-G-R-G-R-G-R-G-R-E-E-G-S-G-A-R-Q-V-R-G-A-G-R-D-V-M-M-Q-V-A-K-A-W-V-E-V-R-G-R-G-A-S-A-G-K-S-G-G-R-G-G-R-G-R-G"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-I-V-Y-Q-D-L-L-S-G-D-E-L-L-S-D-S-F-P-Y-K-E-L-Y-N-G-V-L-W-E-V-E-G-K-W-V-V-Q-G-A-V-D-V-D-I-G-A-N-P-S-A-E-G-G-D-E-E-G-V-K-I-R-L-V-K-V-V-D-I-V-D-T-F-R-L-Q-E-Q-P-P-F-D-K-K-Q-F-L-G-F-I-K-R-Y-I-K-N-L-A-T-K-L-S-E-E-R-Q-A-E-F-K-K-N-V-E-G-A-A-K-M-L-V-S-K-L-S-D-L-Q-F-F-V-G-E-S-M-H-D-D-G-S-M-V-F-A-Y-Y-K-D-G-A-T-D-P-T-F-L-Y-F-A-D-G-L-K-E-V-K-C"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-V-Y-Q-D-L-L-T-G-D-E-L-L-S-D-S-F-P-Y-K-E-I-H-N-G-I-L-W-E-V-E-G-K-W-V-V-Q-G-A-V-D-V-D-I-G-A-N-P-S-A-E-G-A-D-E-D-E-G-V-D-D-Q-A-V-K-V-V-D-I-V-D-T-F-R-L-Q-E-Q-P-A-F-D-K-K-Q-F-V-T-Y-M-K-R-F-I-K-L-L-T-P-K-L-D-E-E-K-Q-E-S-F-K-K-N-I-E-G-A-T-K-F-L-L-S-K-L-S-D-L-Q-F-F-V-G-E-S-M-H-D-D-G-S-L-V-F-A-Y-Y-R-G-G-A-T-D-P-T-F-L-Y-F-A-Y-A-L-K-E-V-K-C"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -M-A-G-L-M-K-L-G-C-L-V-F-V-F-V-I-A-A-G-P-I-T-A-K-A-A-L-S-C-G-E-V-N-S-N-L-K-P-C-T-G-Y-L-T-N-G-G-I-T-S-P-G-P-Q-C-C-N-G-V-R-K-L-N-G-M-V-L-T-T-L-D-R-R-Q-A-C-R-C-I-K-N-A-A-R-N-V-G-P-G-L-N-A-D-R-A-A-G-I-P-R-R-C-G-I-K-I-P-Y-S-T-Q-I-R-F-N-T-K-C-N-T-Y-I-C"} +{"text": "### FUNCTION Probable cyclin-dependent protein kinase inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle ### SEQUENCE -M-G-F-S-D-A-G-I-Y-L-S-D-P-N-N-L-C-Q-T-E-L-G-F-F-H-E-P-S-L-G-F-S-D-Q-S-D-P-Q-N-E-F-H-I-T-P-P-I-Y-Q-E-L-Q-D-Q-D-L-E-P-K-S-Q-E-T-N-N-C-S-R-K-E-G-A-T-V-K-K-E-E-E-E-E-D-D-Y-C-K-T-P-T-R-S-D-Q-I-L-S-A-M-P-R-I-C-P-P-A-P-R-K-P-K-R-V-P-S-R-S-L-K-V-R-N-S-Y-R-S-K-R-M-I-I-L-N-V-S-R-E-I-D-C-L-F-N-P-T-S-L-C-N-K-I-K-K-A-R-Y-I"} +{"text": "### FUNCTION Functions as downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' ### SEQUENCE -M-I-N-L-H-N-A-E-N-E-K-E-A-E-M-Q-I-G-T-P-T-D-V-K-H-V-A-H-I-G-W-D-G-G-S-V-N-H-N-P-P-S-W-M-K-D-F-K-V-L-G-G-Y-S-P-A-L-I-G-N-I-K-E-D-A-S-C-I-F-E-D-S-T-R-S-R-D-I-P-R-L-P-K-S-S-R-E-R-S-S-T-L-G-G-S-P-T-K-E-R-S-R-R-R-G-S-S-Q-Y-N-G-N-P-K-V-S-R-R-S-S-K-E-S-S-A-I-P-Q-D-G-G-F-N-K-K-S-R-R-K-K-S-K-D-C-V-D-G-G-S-R-R-S-S-R-R-V-R-G-S-Q-V-E-S-I-S-D-S-S-S-T-S-D-A-G-Y-L-T"} +{"text": "### FUNCTION May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments ### SEQUENCE -M-L-A-P-G-E-S-V-L-I-P-A-E-E-I-S-L-S-A-G-D-V-I-S-L-S-V-H-N-L-I-A-S-V-S-S-Y-R-P-W-W-S-E-F-L-A-F-G-S-I-D-R-P-S-S-F-S-P-A-V-S-R-V-K-L-N-L-H-H-F-A-V-N-Y-V-L-L-T-A-A-S-I-T-L-F-L-I-G-D-P-M-A-L-V-T-V-A-S-F-V-A-M-W-L-L-L-Y-F-Y-R-D-H-P-L-V-L-Y-G-R-H-I-S-D-R-V-I-V-F-G-L-I-L-G-S-L-W-A-L-W-F-I-N-S-L-Q-C-L-I-L-G-V-V-T-S-V-L-L-C-L-V-H-A-I-I-R-N-S-D-D-L-F-V-Q-E-K-D-V-V-V-P-S-N-F-L-H-W-S"} +{"text": "### FUNCTION Subunit of the oligosaccharyl transferase All subunits are required for a maximal enzyme activity ### SEQUENCE -M-A-R-S-T-G-K-D-A-Q-A-L-F-H-S-L-R-S-A-Y-A-A-T-P-T-T-L-K-I-I-D-L-Y-V-G-F-A-V-F-T-A-L-I-Q-V-V-Y-M-A-I-V-G-S-F-P-F-N-S-F-L-S-G-V-L-S-C-V-G-T-A-V-L-A-V-C-L-R-I-Q-V-N-K-D-N-K-E-F-K-D-L-P-P-E-R-A-F-A-D-F-V-L-C-N-L-V-L-H-L-V-I-M-N-F-L-G"} +{"text": "### FUNCTION Produces a lesion in the cytoplasmic membrane allowing the phage lysosyme to attack the peptidoglycan ### SEQUENCE -M-W-M-N-F-E-S-L-Q-I-A-R-A-Y-L-F-G-E-V-K-Y-L-D-L-M-L-V-L-N-I-I-D-I-I-T-G-V-I-K-A-W-K-F-K-E-L-R-S-R-S-A-W-F-G-Y-V-R-K-M-L-S-F-L-V-V-I-V-A-N-A-I-D-T-I-M-D-L-N-G-V-L-T-F-A-T-V-L-F-Y-I-A-N-E-G-L-S-I-T-E-N-L-A-Q-I-G-V-K-I-P-A-V-I-T-D-R-L-H-V-I-E-S-D-N-D-Q-K-T-E-K-D-D-Q-A-A-G"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-V-Y-F-M-F-I-M-L-V-G-L-I-L-G-L-M-A-V-A-S-N-P-S-P-Y-F-A-A-L-G-L-V-V-A-A-G-V-G-C-G-L-L-V-G-H-G-G-S-F-L-S-L-V-L-F-L-I-Y-L-G-G-M-L-V-V-F-A-Y-T-A-A-L-A-A-E-P-Y-P-E-T-W-G-D-W-S-V-L-L-Y-V-S-V-Y-L-L-G-I-F-F-V-G-K-Y-F-F-K-E-W-G-G-L-G-W-V-G-V-E-E-M-S-N-L-E-M-I-R-G-D-F-G-G-V-A-L-L-Y-A-N-G-G-I-M-L-V-L-G-G-W-V-L-L-L-T-L-F-V-I-L-E-L-T-R-G-L-S-Y-G-T-L-R-V-V"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-N-L-I-M-S-S-V-A-A-T-A-L-I-S-L-I-L-A-F-V-A-F-W-L-P-S-L-N-P-D-N-E-K-L-S-P-Y-E-C-G-F-D-P-L-G-S-A-R-L-P-F-S-L-R-F-F-L-V-A-I-L-F-L-L-F-D-L-E-I-A-L-L-L-P-L-P-W-G-N-Q-L-L-T-P-S-I-S-L-L-W-A-T-S-I-I-I-L-L-T-L-G-L-I-Y-E-W-L-Q-G-G-L-E-W-A-E"} +{"text": "### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-T-Y-I-V-S-L-F-L-L-G-L-V-L-G-L-V-A-V-A-S-N-P-A-P-Y-F-A-A-L-G-L-V-V-A-A-G-V-G-C-G-V-L-V-G-Y-G-G-S-F-L-S-L-V-L-F-L-I-Y-L-G-G-M-L-V-V-F-A-Y-S-A-A-L-A-A-E-P-F-P-E-S-W-G-D-R-S-V-L-G-Y-V-V-V-Y-T-V-G-V-M-L-V-A-G-W-F-W-S-G-W-Y-E-T-S-W-V-V-V-D-E-F-K-E-F-S-V-L-R-G-D-T-S-G-V-A-L-M-Y-S-Y-G-G-G-M-L-I-V-C-A-W-V-L-L-L-T-L-F-V-V-L-E-L-T-R-G-L-S-R-G-A-L-R-A-V"} +{"text": "### FUNCTION Weakly inhibits the Kv13/KCNA3 channel ### SEQUENCE -M-K-S-V-C-G-V-L-I-I-L-V-V-L-T-T-M-L-S-I-S-T-F-S-T-V-G-A-E-A-D-C-P-I-S-E-A-I-K-C-V-E-K-C-K-E-K-V-E-V-C-E-P-G-V-C-K-C-S-G"} +{"text": "### FUNCTION Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles ### SEQUENCE -M-V-L-S-D-G-E-W-Q-L-V-L-N-I-W-A-K-V-E-A-D-V-A-G-H-G-Q-D-V-L-I-R-L-F-K-G-H-P-E-T-L-E-K-F-D-K-F-K-H-L-K-T-E-A-E-M-K-A-S-E-D-L-K-K-H-G-N-T-V-L-T-A-L-G-G-I-L-K-K-K-G-H-H-E-A-E-L-K-P-L-A-Q-S-H-A-T-K-H-K-I-P-I-K-Y-L-E-F-I-S-D-A-I-I-H-V-L-H-S-R-H-P-G-D-F-G-A-D-A-Q-G-A-M-N-K-A-L-E-L-F-R-K-D-I-A-A-K-Y-K-E-L-G-F-Q-G"} +{"text": "### FUNCTION Part of the gene cluster that mediates the biosynthesis of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties ### SEQUENCE -M-A-T-E-L-K-E-Y-L-V-I-I-P-D-L-P-D-V-L-A-K-R-Q-V-L-L-K-P-H-N-Q-D-A-A-P-L-V-K-A-G-R-V-P-F-F-G-S-T-L-A-H-H-S-A-E-G-Q-Q-V-A-E-N-G-T-V-M-I-I-K-A-E-S-E-E-E-I-K-E-I-I-R-K-D-I-F-T-I-E-G-V-W-D-F-G-K-L-S-I-W-P-F-K-S-K"} +{"text": "### FUNCTION May function as a protein modifier covalently attached to lysine residues of substrate proteins This may serve to target the modified proteins for degradation by proteasomes ### SEQUENCE -M-S-D-L-F-R-M-E-E-R-R-Q-M-P-I-L-P-T-E-P-A-R-K-E-G-D-G-G-G-P-Q-K-P-D-V-K-R-P-D-T-S-D-L-L-R-R-M-K-R-V-D-P-D-A-A-R-R-Y-R-Q-R-S-G-E"} +{"text": "### FUNCTION Inhibits insect, but not mammalian, voltage-gated calcium channels ### SEQUENCE -M-N-T-A-T-G-V-I-A-L-L-V-L-A-T-V-I-G-C-I-E-A-E-T-R-A-D-L-Q-G-A-F-E-S-Y-E-G-E-A-A-E-K-I-F-R-R-S-P-T-C-I-P-S-G-Q-P-C-P-Y-N-E-N-C-C-S-K-S-C-T-Y-K-E-M-K-T-A-T-P-V-Q-R-C-D"} +{"text": "### FUNCTION Toxin that may inhibit ion channels ### SEQUENCE -M-N-T-A-T-G-F-I-V-L-L-V-L-A-T-V-L-G-G-I-E-A-G-E-S-H-M-R-K-D-A-M-G-R-V-R-R-Q-Y-C-V-P-V-D-Q-P-C-S-L-N-T-Q-P-C-C-D-D-A-T-C-T-Q-E-L-N-E-N-D-N-T-V-Y-Y-C-R-A"} +{"text": "### FUNCTION Inhibits insect, but not mammalian, voltage-gated calcium channels ### SEQUENCE -M-N-T-A-T-G-F-I-V-L-L-V-L-A-T-V-I-G-C-I-S-A-D-F-Q-G-G-F-E-P-Y-E-G-E-D-A-E-R-I-F-R-R-S-P-T-C-I-P-T-G-Q-P-C-P-Y-N-E-N-C-C-S-Q-S-C-T-Y-K-A-N-E-N-G-N-Q-V-K-G-C-D"} +{"text": "### FUNCTION Inhibits insect, but not mammalian, voltage-gated calcium channels ### SEQUENCE -M-N-T-A-T-G-F-I-V-L-L-V-L-A-T-V-I-G-C-I-S-A-D-F-Q-G-G-F-E-P-Y-E-E-E-D-A-E-R-I-F-R-R-S-P-T-C-I-P-T-G-Q-P-C-P-Y-N-E-N-C-C-N-Q-S-C-T-Y-K-A-N-E-N-G-N-Q-V-K-R-C-D"} +{"text": "### FUNCTION Inhibits insect, but not mammalian, voltage-gated calcium channels ### SEQUENCE -M-N-T-A-T-G-V-I-A-L-L-V-L-A-T-V-I-G-C-I-E-A-E-E-T-R-A-D-L-Q-G-A-F-E-S-Y-E-G-E-A-A-D-K-I-F-R-R-S-P-T-C-I-P-S-G-Q-P-C-P-Y-N-E-N-C-C-S-K-S-C-T-Y-K-E-N-E-N-G-N-T-V-Q-R-C-D"} +{"text": "### FUNCTION Inhibits insect, but not mammalian, voltage-gated calcium channels ### SEQUENCE -M-N-T-A-T-G-F-I-V-L-L-V-L-A-T-V-I-G-C-I-S-A-D-F-Q-G-G-F-E-P-Y-E-E-E-D-A-E-R-I-F-R-R-S-P-T-C-I-P-T-G-Q-P-C-P-Y-N-E-N-C-C-S-Q-S-C-T-Y-K-T-N-E-N-G-N-Q-V-K-G-C-D"} +{"text": "### FUNCTION Toxin that may inhibit ion channels ### SEQUENCE -M-N-T-A-T-G-F-I-V-L-L-V-L-A-T-V-L-G-G-I-E-A-G-E-S-H-M-R-K-D-A-M-G-R-V-R-R-Q-Y-C-V-P-V-D-Q-P-C-S-L-N-T-Q-P-C-C-D-D-A-T-C-T-Q-E-L-N-E-N-D-N-T-V-Y-Y-C-R-A"} +{"text": "### FUNCTION Toxin that may inhibit ion channels ### SEQUENCE -M-N-T-A-T-G-F-I-V-L-L-V-L-A-T-I-L-G-G-I-E-A-G-E-S-H-M-R-K-D-A-M-G-R-V-R-R-Q-Y-C-V-P-V-D-Q-P-C-S-L-N-T-Q-P-C-C-D-D-A-T-C-T-Q-E-R-N-E-N-G-H-T-V-Y-Y-C-R-A"} +{"text": "### FUNCTION Inhibits insect, but not mammalian, voltage-gated calcium channels ### SEQUENCE -M-N-T-A-T-G-F-I-V-L-L-V-L-A-T-V-I-G-C-I-S-A-D-F-Q-G-S-F-E-P-Y-E-E-E-D-A-E-R-I-F-R-R-S-T-C-T-P-T-D-Q-P-C-P-Y-D-E-S-C-C-S-G-S-C-T-Y-K-A-N-E-N-G-N-Q-V-K-R-C-D"} +{"text": "### FUNCTION Plays a role as a neuroprotective and antiapoptotic factor ### SEQUENCE -M-D-T-Q-G-F-S-C-L-L-L-L-I-S-E-I-D-L-S-V-K-R-R-I"} +{"text": "### FUNCTION Plays a role as a neuroprotective and antiapoptotic factor ### SEQUENCE -M-A-T-R-G-F-S-C-L-L-L-V-I-S-E-I-D-L-S-V-K-R-W-V"} +{"text": "### FUNCTION Catalyzes the reduction of flavin by NADH Subsequently, the reduced flavins is transferred to the tetracycline 7-halogenase CtcP ### SEQUENCE -M-P-P-E-P-L-S-L-P-L-D-L-A-P-G-L-V-D-G-D-T-F-L-S-I-M-G-A-L-P-T-G-V-T-V-V-T-T-L-G-P-D-G-E-P-Y-G-L-T-C-S-A-A-C-S-V-S-K-A-P-P-L-L-L-V-C-I-N-R-D-S-R-V-L-K-A-L-L-E-R-G-E-F-A-V-N-V-L-R-G-G-G-E-S-T-S-A-R-F-A-A-P-V-D-D-R-F-R-D-V-R-W-E-P-G-S-A-G-G-V-P-V-M-S-A-D-V-V-A-H-A-E-C-R-V-A-A-A-L-D-A-G-D-H-T-I-V-I-G-A-V-V-A-G-G-P-R-P-E-V-P-S-P-L-M-Y-W-R-R-S-Y-A-R-W-P-V-E-E-D-P-R-T-A-A-L-T-L-A-A-E-G"} +{"text": "### FUNCTION May act as a pheromone ### SEQUENCE -N-D-Y-A-E-L-E-G-K-W-D-T-I-A-I-A-A-D-N-D-A-K-I-K-E-E-G-P-L-R-L-Y-V-R-E-L-Y-C-N-E-D-C-S-E-M-E-V-T-F-Y-V-N-A-N-N-Q-C-S-K-T-T-V-I-G-Y-K-Q-A-D-G-T-Y-R-T-Q-F-E-G-D-N-R-F-Q-P-V-Y-A-T-P-E-N-I-V-F-T-S-K-N-V-D-R-A-G-Q-E-T-N-L-I-F-V-V-G-K-S-Q-P-L-T-P-E-Q-H-E-K-L-V-E-F-A-H-E-N-N-I-P-E-E-N-I-H-N-V-L-A-T-D-T-C-P-K"} +{"text": "### FUNCTION Part of the gene cluster that mediates the biosynthesis of oxopyrrolidines, polyketide-amino acid hybrid compounds with feature structures of tetramic acid ### SEQUENCE -M-R-G-Y-R-S-S-Q-R-T-F-F-R-G-F-D-P-R-H-A-Y-R-F-R-G-D-G-R-H-G-G-M-G-G-A-L-K-I-V-F-L-G-M-M-T-Y-F-I-A-K-K-A-F-R-S-S-Q-H-P-P-T-D-F-N-A-P-V-Q-S-V-P-Q-R-A-Q-R-P-S-D-T-R-L-Q-G-P-V-L-L-A-S-N-H-P-S-G-D-S-A-S-P-E"} +{"text": "### FUNCTION Part of the gene cluster that mediates the biosynthesis of oxaleimides, cytotoxic compounds containing an unusual disubstituted succinimide moiety ### SEQUENCE -M-A-L-D-L-L-V-V-S-A-G-S-L-A-L-K-V-L-R-V-T-P-L-I-T-T-T-I-L-L-V-N-R-L-A-Q-Y-F-A-L-S-T-F-L-P-P-H-T-S-P-K-K-I-D-H-V-G-A-A-F-Q-H-W-L-Q-T-V-V-P-R-V-W-T-G-V-I-S-I-V-L-F-T-R-V-A-L-I-L-N-L-F-V-R-P-D-D-L-A-G-S-N-A-R-F-L-Y-G-V-G-L-F-L-S-F-A-H-L-S-V-A-P-K-M-L-K-F-E-K-R-M-M-S-P-E-T-V-P-H-V-A-M-E-L-L-A-G-W-M-K-V-N-N-I-R-F-W-I-V-D-V-P-F-W-V-V-G-V-W-A-T-L-E-G-L-K-A"} +{"text": "### FUNCTION Venom protein that causes edema, enhances vascular permeability and is likely related to the inflammatory activity of the venom ### SEQUENCE -M-I-I-Y-R-D-C-I-S-Q-D-E-M-F-S-D-I-Y-K-I-T-E-V-A-N-G-L-C-L-E-V-E-G-K-M-V-S-R-K-E-G-E-I-D-D-A-L-I-G-G-N-A-S-A-E-G-P-E-G-D-G-T-E-A-T-V-I-T-G-V-D-I-V-M-N-H-H-L-Q-E-T-S-F-T-K-E-S-Y-K-K-Y-I-K-D-Y-M-K-S-I-K-A-R-L-E-E-T-K-P-E-R-V-K-P-F-M-T-G-A-A-E-Q-V-K-H-I-L-G-N-F-K-N-Y-Q-F-F-V-G-E-N-M-N-P-D-G-M-V-G-L-L-D-F-R-E-D-G-V-T-P-Y-M-I-F-F-K-D-G-L-E-M-E-K-C"} +{"text": "### FUNCTION Venom protein that causes edema, enhances vascular permeability and is likely related to the inflammatory activity of the venom ### SEQUENCE -M-I-I-Y-R-D-C-I-S-Q-D-E-M-F-S-D-I-Y-K-I-T-E-V-A-N-G-L-C-L-E-V-E-G-K-M-V-S-R-K-E-G-E-I-D-E-A-L-I-G-G-N-A-S-A-D-G-P-E-D-C-T-E-A-T-V-I-T-G-V-D-I-V-M-N-H-H-L-Q-E-T-S-F-T-K-E-S-Y-K-K-Y-I-K-D-Y-M-K-S-I-K-A-R-L-E-E-S-K-P-E-R-V-K-P-F-M-T-G-A-A-E-Q-V-K-H-I-L-G-N-F-K-N-Y-Q-F-F-V-G-E-N-M-N-P-D-G-M-V-G-L-L-D-F-R-E-D-G-V-T-P-Y-M-I-F-F-K-D-G-L-E-M-E-K-C"} +{"text": "### FUNCTION Possible increased expression of this protein ### SEQUENCE -M-K-P-A-L-R-D-F-I-A-I-V-Q-E-R-L-A-S-V-T-A"} +{"text": "### FUNCTION Antimicrobial peptide with high activity against Gram-positive bacteria, low activity against Gram-negative bacteria, and moderate activity against fungi ### SEQUENCE -M-A-F-L-K-K-S-L-F-L-V-L-F-L-G-L-V-S-L-S-I-C-E-E-E-K-R-E-T-E-E-E-E-H-D-Q-E-E-D-D-K-S-E-E-K-R-F-L-S-L-I-P-H-I-V-S-G-V-A-S-I-A-K-H-L-G"} +{"text": "### FUNCTION Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths ### SEQUENCE -M-S-D-I-N-T-T-R-L-P-F-V-F-V-A-S-P-P-C-V-G-D-D-I-A-M-V-L-T-R-G-E-N-L-C"} +{"text": "### FUNCTION Toxin that belongs to the bicyclic heptapeptides called phallotoxins ### SEQUENCE -M-S-D-I-N-A-T-R-L-P-A-W-L-V-D-C-P-C-V-G-D-D-V-N-R-L-L-T-R-G-E-S-L-C"} +{"text": "### FUNCTION Cyclic nonapeptide that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths ### SEQUENCE -M-S-D-I-N-T-A-R-L-P-V-F-S-L-P-V-F-F-P-F-V-S-D-D-I-Q-A-V-L-T-R-G-E-S-L-C"} +{"text": "### FUNCTION Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths ### SEQUENCE -M-S-D-I-N-A-T-R-L-P-A-W-L-T-D-C-P-C-V-G-D-D-V-N-R-L-L-T-R-G-E-S-L-C"} +{"text": "### FUNCTION Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths ### SEQUENCE -M-S-D-I-N-A-T-R-L-P-F-V-F-V-A-S-P-P-C-V-G-D-D-I-A-M-V-L-T-R-G-E-N-L-C"} +{"text": "### FUNCTION Cyclic nonapeptide that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths ### SEQUENCE -M-S-D-I-N-A-T-R-L-P-V-F-S-L-P-V-F-F-P-F-V-S-D-D-I-Q-A-V-L-T-R-G-E-S-L-C"} +{"text": "### FUNCTION Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths ### SEQUENCE -M-S-D-I-N-A-T-R-L-P-L-F-F-P-P-D-F-R-P-P-C-V-G-D-A-D-N-F-T-L-T-R-G-E-N-L-C"} +{"text": "### FUNCTION Toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters ### SEQUENCE -M-S-D-I-N-A-T-R-L-P-I-W-G-I-G-C-D-P-C-V-G-D-D-V-T-A-L-L-T-R-G-E-A-L-C"} +{"text": "### FUNCTION Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths ### SEQUENCE -M-S-D-I-N-V-I-R-A-P-L-L-I-L-S-I-L-P-C-V-G-D-D-I-E-V-L-R-R-G-E-G-L-S"} +{"text": "### FUNCTION Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths ### SEQUENCE -M-S-D-I-N-A-T-R-L-P-I-F-W-F-I-Y-F-P-C-V-S-D-V-D-S-T-L-T-R-G-E-R"} +{"text": "### FUNCTION Major toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters ### SEQUENCE -M-S-D-I-N-A-T-R-L-P-I-W-G-I-G-C-N-P-C-V-G-D-D-V-T-S-V-L-T-R-G-E-A"} +{"text": "### FUNCTION Major toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters ### SEQUENCE -M-S-D-I-N-A-T-R-L-P-I-W-G-I-G-C-N-P-C-V-G-D-D-V-T-S-V-L-T-R-G-E-A-L-C"} +{"text": "### FUNCTION Major toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters ### SEQUENCE -M-S-D-I-N-A-T-R-L-P-I-W-G-I-G-C-N-P-C-V-G-D-E-V-A-A-L-L-T-R-G-E-A-L-C"} +{"text": "### FUNCTION Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths ### SEQUENCE -M-S-D-I-N-A-T-R-L-P-I-I-W-A-P-V-V-P-C-I-S-D-D-N-D-S-T-L-T-R-G-Q-R"} +{"text": "### FUNCTION Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex ### SEQUENCE -M-M-S-K-I-V-L-V-G-L-V-G-S-A-A-A-F-N-A-P-M-M-T-V-R-R-D-A-I-A-T-G-A-A-A-A-V-V-A-P-I-L-R-P-A-G-A-A-M-K-K-N-S-K-A-P-C-V-T-I-F-D-E-R-D-G-C-G-G-P-T-R-A-K-T-G-A-G-E-E-G-L-M-V-K-I-Q-M-Q-E-I-K-L-G-R-G-A-G-A-E-Y-V-S-I-F-T-N-Y-D-K-K-L-F-G-V-K"} +{"text": "### FUNCTION Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex ### SEQUENCE -M-I-A-K-T-A-V-A-L-A-L-V-A-S-A-V-A-L-R-P-T-M-S-L-S-A-N-R-R-E-V-V-A-G-A-G-A-A-A-V-V-A-P-M-L-R-P-A-E-A-N-A-V-Y-T-R-G-T-S-L-S-A-P-V-I-T-I-F-D-A-R-G-C-T-D-H-A-N-K-E-Y-K-G-D-W-S-G-R-A-E-D-D-E-C-C-V-K-I-Q-M-Q-K-I-S-V-A-E-D-V-A-R-L-V-R-L-E-C-L-N-E-L-K-S-K"} +{"text": "### FUNCTION Salivary chemokine-binding protein which binds to host chemokines CXCL1, CXCL2, CXCL5 and CXCL8 ### SEQUENCE -M-E-V-K-T-F-A-F-L-Q-I-A-V-F-I-A-L-G-A-Q-I-F-L-A-G-T-D-A-L-S-D-E-D-E-L-F-S-V-E-Y-C-G-T-N-C-T-K-Q-D-T-G-S-W-T-T-C-S-G-N-C-T-C-Y-H-E-D-G-K-K-V-G-L-C-L-S-T-E-Y-T-D-F-T-K-F-P-K-P-T-S-E-E-I-A-N-A-R-P-L-P-K-R-E-K-T-L-N"} +{"text": "### FUNCTION Salivary chemokine-binding protein which has chemokine-neutralizing activity and binds to host chemokines CXCL1, CXCL2, CXCL3, CXCL5, CXCL6 and CXCL8 ### SEQUENCE -M-E-V-K-T-Y-A-F-L-Q-I-A-V-F-I-F-L-G-M-Q-I-F-A-S-L-T-D-A-A-D-D-D-N-E-L-F-T-V-Q-Y-C-G-M-N-C-T-K-D-E-G-G-T-W-T-G-C-T-G-K-K-E-G-C-K-C-Y-H-E-S-G-K-N-Y-G-L-C-L-S-T-E-Y-T-D-F-S-Q-Y-G-N-P-S-D-S-E-I-E-A-A-K-P-K-R-S-D-T-L-S-H"} +{"text": "### FUNCTION Salivary chemokine-binding protein which binds to host chemokines CXCL1, CXCL2, CXCL5 and CXCL8 ### SEQUENCE -F-L-L-K-S-Q-L-C-Y-C-L-F-G-I-E-L-I-G-A-G-I-H-A-L-H-E-D-E-I-F-T-V-D-Y-C-G-T-N-C-T-K-Q-S-N-G-S-W-T-T-C-P-G-N-C-S-C-Y-H-E-D-G-K-T-D-G-F-C-L-S-T-E-Y-T-D-F-T-Q-F-P-N-L-T-S-E-E-M-D-A-A-T-P-R-P-E"} +{"text": "### FUNCTION Salivary chemokine-binding protein which binds to host chemokines CXCL1 and CXCL8 ### SEQUENCE -L-K-T-F-C-L-F-L-Q-I-A-V-F-I-A-L-G-I-Q-I-F-L-C-G-T-D-A-L-N-N-E-N-E-L-F-S-V-E-Y-C-G-A-N-C-T-Q-Q-D-N-G-S-W-T-K-C-K-G-N-C-T-C-Y-H-E-D-G-K-R-Y-G-L-C-L-S-T-E-Y-T-D-F-T-Q-F-P-K-P-T-S-E-E-I-A-D-A-S-P-R-P-K-E-T-N-S-H"} +{"text": "### FUNCTION Putative toxic component of a possible type II toxin-antitoxin system Its toxic effect may be neutralized by cognate antitoxin Rv3098B/RVBD_3098B ### SEQUENCE -M-V-I-R-G-A-V-Y-R-V-D-F-G-D-A-K-R-G-H-E-Q-R-G-R-R-Y-A-V-V-I-S-P-G-S-M-P-W-S-V-V-T-V-V-P-T-S-T-S-A-Q-P-A-V-F-R-P-E-L-E-V-M-G-T-K-T-R-F-L-V-D-Q-I-R-T-I-G-I-V-Y-V-H-G-D-P-V-D-Y-L-D-R-D-Q-M-A-K-V-E-H-A-V-A-R-Y-L-G-L"} +{"text": "### FUNCTION Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released ### SEQUENCE -M-S-N-L-Y-E-S-I-R-K-Y-K-C-G-Y-I-E-E-I-L-N-I-L-D-M-F-D-P-L-L-N-K-F-Q-R-N-S-C-Y-E-D-M-K-S-E-L-S-L-F-M-F-N-L-I-D-N-F-P-L-E-K-D-C-F-K-E-D-K-F-I-I-N-Y-I-Y-K-S-L-K-N-K-F-I-Q-V-N-K-L-H-Q-K-V-K-S-Y-E-T-N-I-D-I-I-W-V-N-N-C-D-Y-A-N-L-L-S-T-V-I-F-E-D-I-I-K-D-L-T-Q-N-E-K-N-I-L-R-K-I-Y-L-H-G-L-R-E-S-E-I-S-R-E-L-N-I-S-R-Q-A-V-N-K-T-H-L-R-A-L-E-K-L-K-K-L-I-N"} +{"text": "### FUNCTION Might be involved in magnetite crystal growth ### SEQUENCE -M-L-S-A-K-G-V-S-L-G-L-G-L-G-L-G-A-W-G-P-V-L-L-G-V-V-G-V-A-G-A-L-A-L-Y-G-Y-Y-K-N-R-N-A-E-P-A-A-A-E-A-V"} +{"text": "### FUNCTION May increase the toxicity of alpha-latrotoxin and/or other venom components Is non-toxic to mice and to the cockroach Periplaneta americana ### SEQUENCE -M-L-K-L-I-C-I-A-F-L-V-T-V-L-T-L-V-A-G-E-D-S-L-D-P-A-E-Y-G-C-A-D-D-I-N-Q-E-D-L-L-K-K-N-D-V-C-L-Q-C-E-D-L-H-K-E-G-V-V-F-S-L-C-K-T-N-C-F-T-T-Q-Y-F-T-N-C-V-K-D-L-E-E-A-E-K-E-P-P-E"} +{"text": "### FUNCTION May increase the toxicity of alpha-latrotoxin and/or other venom components Is non-toxic to mice and to the cockroach Periplaneta americana ### SEQUENCE -M-S-K-L-H-F-L-I-L-L-S-V-I-V-S-V-F-C-I-E-P-Q-D-I-G-C-T-G-I-S-T-A-E-F-E-E-K-D-A-T-C-S-K-C-E-E-D-Y-S-G-N-G-M-I-D-R-C-R-S-D-C-Y-S-G-P-F-F-K-S-C-V-E-L-L-N-K-G-Y-D-E-K-D-E-N-V-K-P-E-W"} +{"text": "### FUNCTION May increase the toxicity of alpha-latrotoxin and/or other venom components Is non-toxic to mice and to the cockroach Periplaneta americana ### SEQUENCE -M-N-K-L-F-F-V-V-F-L-C-L-I-I-S-V-L-A-I-G-P-A-D-L-G-C-T-D-M-P-Q-A-E-F-D-E-K-N-A-N-C-E-K-C-G-N-E-E-G-F-G-E-E-M-V-S-R-C-R-D-K-C-F-T-D-N-F-Y-Q-S-C-V-D-L-L-N-K-V-Y-E-E-K-D-V-P-V-P-P-E-E"} +{"text": "### FUNCTION May increase the toxicity of alpha-latrotoxin and/or other venom components Is non-toxic to mice and to the cockroach Periplaneta americana ### SEQUENCE -M-L-K-L-I-C-I-V-F-L-V-T-V-L-T-F-V-V-G-E-D-T-L-D-P-A-E-Y-G-C-P-S-D-V-D-M-A-E-L-T-E-K-N-E-V-C-L-R-C-E-D-F-H-K-E-G-V-A-F-T-L-C-K-T-N-C-F-T-T-E-Y-Y-K-N-C-V-K-D-L-E-E-A-G-K-E-T-E-E"} +{"text": "### FUNCTION May increase the toxicity of alpha-latrotoxin and/or other venom components Is non-toxic to mice and to the cockroach Periplaneta americana ### SEQUENCE -M-N-V-L-H-F-L-I-L-L-M-S-V-V-S-V-F-C-I-N-P-E-D-I-G-C-D-D-S-I-T-P-E-K-F-A-E-N-D-A-K-C-V-Q-C-K-E-Q-F-E-E-T-N-M-L-E-Q-C-R-E-D-C-F-K-G-K-F-F-R-S-C-V-D-H-L-S-G-A-Y-D-E-K-D-D-V-E-A-P-P-P-E"} +{"text": "### FUNCTION May increase the toxicity of alpha-latrotoxin and/or other venom components Is non-toxic to mice and to the cockroach Periplaneta americana ### SEQUENCE -M-S-K-L-F-F-V-A-F-L-C-L-I-I-S-V-F-A-T-T-P-D-E-I-G-C-T-D-I-S-Q-A-E-F-D-E-K-N-A-N-C-I-K-C-G-E-E-G-F-G-E-E-M-V-K-R-C-R-N-K-C-F-T-D-N-F-Y-Q-S-C-V-D-Q-L-N-G-V-Y-E-E-K-D-T-P-P-V-K-E"} +{"text": "### FUNCTION May increase the toxicity of alpha-latrotoxin and/or other venom components Is non-toxic to mice and to the cockroach Periplaneta americana ### SEQUENCE -M-F-K-L-I-C-I-V-F-I-A-T-I-L-S-I-T-S-A-A-D-N-E-D-E-L-T-I-E-D-F-L-S-Y-E-C-N-E-S-M-D-I-E-E-L-K-E-K-D-K-V-C-S-R-C-A-N-L-H-K-T-Q-S-V-I-E-R-C-R-L-N-C-F-T-S-E-Y-F-K-N-C-E-D-N-L-Q-A-K-E-E-E-P-E-E-E-T-L"} +{"text": "### FUNCTION Secreted effector that completely suppresses elicitor-induced cell death in host and enhances virulence of Pparasitica ### SEQUENCE -M-R-L-L-L-W-V-L-L-V-T-L-V-T-F-L-S-S-G-D-A-A-P-V-D-S-N-K-Q-L-E-R-A-A-I-N-K-V-T-S-R-N-L-A-N-D-N-S-L-K-H-E-K-R-F-L-R-G-D-R-S-N-I-V-N-L-K-D-G-D-E-N-E-E-R-K-I-G-Q-K-M-T-T-A-L-K-S-I-K-V-W-Y-L-K-W-E-Q-K-I-L-L-P-G-F-K-K-M-A-K-K-E-M-T-Y-S-K-L-M-D-R-F-R-V-R-M-M-N-S-G-R-W-G-T-P-S-G-F-K-R-Y-G-R-L-Y-K-D-Y-L-I-S-I-N-R-A-D-L-T-V"} +{"text": "### FUNCTION Secreted effector that partially suppresses elicitor-induced cell death in host and enhances virulence of Pparasitica ### SEQUENCE -M-R-F-Y-Y-T-L-L-A-T-A-A-A-L-L-V-H-S-D-A-L-S-A-A-A-E-T-S-L-N-Q-L-T-A-V-D-G-T-T-T-T-S-Q-R-F-L-R-R-H-T-D-S-E-T-T-D-N-E-E-R-L-N-S-G-P-I-V-L-D-T-A-K-K-I-D-D-L-F-E-V-E-K-L-D-K-I-L-D-P-K-M-A-D-K-F-L-D-G-K-T-F-F-G-W-L-D-K-S-A-L-D-E-A-L-N-G-N-I-A-Q-K-T-K-V-F-E-H-W-R-E-K-R-L-R-P-K-A-L-T-K-V-L-T-T-D-P-A-V-R-K-K-Y-K-F-V-Y-E-M-Y-D-S-Y-I-K-Y-V-A-R-K-K-L-S-G-L-K-R-N-R-G-D"} +{"text": "### FUNCTION Secreted effector that partially suppresses elicitor-induced cell death in host and enhances virulence of Pparasitica ### SEQUENCE -M-R-P-P-L-L-L-F-L-T-V-T-V-L-V-S-C-A-S-A-V-S-T-G-N-A-A-E-L-R-S-L-R-S-I-K-T-T-T-N-D-D-A-A-E-E-E-R-G-G-F-Y-H-K-F-D-L-N-F-L-D-D-I-F-H-G-L-P-E-Q-F-Q-R-M-R-N-Q-P-E-R-L-R-T-M-F-E-N-W-K-T-G-W-M-S-V-D-D-A-V-A-Y-M-T-R-E-G-L-S-E-K-A-I-S-Q-F-K-A-A-Y-Q-A-Y-L-K-H-K-G"} +{"text": "### FUNCTION Probable neurotoxin with ion channel impairing activity ### SEQUENCE -M-K-P-I-V-Y-M-L-L-F-C-A-F-T-V-V-I-L-G-H-P-N-N-H-G-A-L-I-P-H-H-D-K-L-P-N-G-E-S-C-T-R-P-G-Y-S-C-S-E-S-S-Q-C-C-T-P-V-D-G-E-T-F-T-Y-G-C-G-R-A-W-M-E-G-S-K-I-C-Y-I-C-N-R-E-S-S-M-C"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-K-E-G-V-N-Q-K-Q-K-K-E-V-T-Q-N-E-F-R-E-E-Y-L-N-E-M-A-A-M-S-L-V-Q-Q-L-E-A-I-E-R-A-L-F-E-N-E-A-G-R-N-S-R-Q-K-R-C-L-G-E-N-V-P-C-G-D-N-I-P-C-C-G-K-L-A-C-E-K-T-A-G-Y-G-W-W-Y-K-S-P-Y-C-V-K-P-T-S-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-F-L-V-L-V-L-A-T-K-F-G-D-A-N-E-G-V-N-R-E-Q-T-K-E-V-I-Q-N-E-F-R-G-D-F-L-N-E-M-A-A-M-S-L-L-Q-Q-L-E-A-I-E-S-A-L-L-E-K-E-A-D-R-N-S-R-Q-K-R-C-N-G-K-N-V-P-C-G-S-N-H-S-P-C-C-S-G-L-S-C-E-E-T-F-G-Y-G-W-L-Y-K-S-P-Y-C-V-I-P-S-N-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-K-E-G-V-N-Q-K-Q-K-K-E-V-T-Q-N-E-F-R-E-E-Y-L-N-E-M-A-A-M-S-L-V-Q-Q-L-E-A-I-E-R-A-L-F-E-N-E-A-G-R-N-S-R-Q-K-R-C-N-G-E-N-V-P-C-G-P-N-H-S-T-C-C-S-G-L-S-C-E-E-T-F-G-Y-G-W-W-Y-A-S-P-Y-C-V-K-P-S-K-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-M-K-Y-F-L-V-L-C-L-V-V-L-A-V-A-A-V-Q-A-A-G-L-E-E-E-K-F-L-N-L-G-E-S-L-A-M-P-E-E-S-R-C-K-A-R-R-Y-G-C-T-D-K-A-E-C-C-S-E-K-C-A-Y-P-A-L-T-C-V-F-N-W-S-C-E-K-V-C-A"} +{"text": "### FUNCTION Probable neurotoxin with ion channel impairing activity ### SEQUENCE -M-K-P-I-V-S-I-L-L-F-C-A-L-A-V-V-I-M-G-H-P-M-N-Q-G-Y-G-I-P-H-D-V-V-K-L-P-N-G-Q-W-C-K-T-P-G-D-D-C-S-K-S-S-E-C-C-K-A-K-D-T-V-T-Y-S-S-G-C-S-Q-E-W-S-G-Q-L-G-G-F-V-K-L-C-H-I-C-N-V-E-S-S-M-C"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-M-K-L-Y-S-L-V-I-I-A-T-L-A-A-A-A-F-A-A-T-S-E-E-I-S-A-A-V-G-E-I-I-S-Q-H-Q-E-D-L-E-R-Y-A-K-V-V-E-R-G-E-E-P-K-K-Y-I-R-C-S-K-Q-L-G-E-S-C-Y-L-N-C-E-C-C-G-A-A-A-V-C-E-D-Y-K-Y-I-C-K-E-K-V-S-D-N-S-V-L-N-A-L-G-Q-A-W-N-A-V-G-N-S-I-S-R-Y-Y-C-D-A-E"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-M-I-A-W-L-V-L-L-T-F-A-A-A-L-C-F-A-D-E-G-L-K-Q-E-H-M-N-E-R-K-K-S-R-F-R-E-D-I-P-D-E-I-S-E-D-L-L-L-Q-E-M-E-A-M-E-A-E-L-L-E-K-E-M-R-M-E-E-N-R-N-S-R-E-K-R-C-L-G-E-D-I-S-C-G-E-K-P-G-D-L-V-R-M-P-C-C-A-K-Y-E-C-K-E-T-A-G-Y-W-W-Y-Q-K-R-F-C-V-K-K-K-S-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-L-V-L-V-A-V-L-G-L-A-S-L-Y-L-L-S-Y-A-S-E-V-Q-Q-L-S-V-A-E-E-E-F-G-A-L-I-D-A-F-G-G-L-L-E-T-E-E-R-G-V-N-K-E-G-C-R-K-F-L-G-G-C-E-N-T-G-Q-C-C-L-H-L-F-C-K-Y-D-T-P-F-N-H-F-C-A-W-D-L-S-F-G-R-K"} +{"text": "### FUNCTION Probable neurotoxin with ion channel impairing activity ### SEQUENCE -M-K-P-I-V-Y-M-L-L-F-C-A-F-T-V-V-I-L-G-H-P-N-N-H-G-A-L-I-P-H-H-D-K-L-P-N-G-E-S-C-T-R-P-G-Y-S-C-S-E-S-N-Q-C-C-T-P-V-D-G-E-T-F-T-Y-G-C-G-R-A-W-M-E-G-S-K-I-C-Y-I-C-N-R-E-S-S-M-C"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-K-E-G-V-N-Q-K-Q-K-K-E-V-T-Q-N-E-F-R-E-E-Y-L-N-E-M-A-A-M-S-L-V-Q-Q-L-E-A-I-E-R-A-L-F-E-N-E-A-G-R-N-S-R-Q-K-R-C-L-G-E-N-V-P-C-G-D-N-I-P-C-C-G-K-L-S-C-E-K-T-F-G-Y-P-W-W-Y-K-S-P-Y-C-V-K-P-S-S-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-K-E-G-V-N-Q-K-Q-K-K-E-V-T-Q-N-E-F-R-E-E-Y-L-N-E-M-A-A-M-S-L-V-Q-Q-L-E-A-I-E-R-A-L-F-E-N-E-A-G-R-N-S-R-Q-K-R-C-N-G-K-N-V-P-C-G-A-N-H-S-P-C-C-S-G-L-S-C-E-E-T-F-G-Y-G-W-L-Y-K-S-P-Y-C-V-I-P-S-N-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-N-E-G-V-N-Q-E-Q-M-K-E-V-I-Q-N-E-F-R-E-D-F-L-N-E-M-A-P-M-S-L-L-Q-Q-L-E-A-I-E-S-T-L-L-E-K-E-A-D-R-N-S-R-Q-K-R-C-N-G-K-N-V-P-C-G-S-N-H-S-P-C-C-S-G-L-S-C-E-E-T-F-G-Y-G-W-L-Y-K-S-P-Y-C-V-I-P-S-N-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-L-S-V-I-V-L-V-A-S-F-G-F-A-V-A-L-P-S-K-K-R-E-E-T-A-A-E-N-E-L-T-G-D-Q-Q-D-A-E-Q-H-M-I-Y-A-V-A-F-P-E-I-R-T-S-C-V-I-G-W-K-Q-Q-G-A-T-C-E-R-D-C-E-C-C-G-V-A-A-T-C-I-T-G-D-K-S-T-G-F-C-G-Y-H-Q-T-P-N-V-L-G-Q-G-I-L-Y-T-A-D-T-I-K-N-G-F-S-A-I-F-C-A-G"} +{"text": "### FUNCTION Probable neurotoxin with ion channel impairing activity ### SEQUENCE -M-K-S-I-V-S-I-L-L-F-C-A-L-A-V-V-I-M-G-H-R-L-N-Q-G-Y-G-I-P-H-D-V-V-K-L-P-N-G-Q-W-C-K-T-P-G-D-D-C-S-Q-S-S-E-C-C-K-A-K-D-T-V-T-Y-S-S-G-C-S-Q-Q-W-S-G-Q-Q-G-G-F-V-N-L-C-R-I-C-N-V-E-S-S-M-C"} +{"text": "### FUNCTION Probable neurotoxin with ion channel impairing activity ### SEQUENCE -M-K-S-I-V-Y-M-L-L-F-C-T-F-T-V-V-I-L-G-H-P-N-D-H-G-A-L-I-P-Y-R-A-E-K-L-P-N-G-E-W-C-I-R-P-G-Y-S-C-S-E-R-G-Q-C-C-M-P-V-D-G-D-T-Y-T-Y-G-C-G-R-A-W-S-E-G-S-K-V-C-F-I-C-N-R-E-S-S-M-C"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-K-E-G-V-N-Q-E-Q-K-K-E-V-T-Q-N-E-F-R-V-E-Y-L-N-E-M-A-A-M-S-L-L-Q-Q-L-E-A-X-E-S-A-L-F-E-K-E-A-G-R-N-S-R-Q-X-R-C-A-M-G-D-V-P-C-T-K-G-K-T-N-C-C-K-G-Y-E-C-K-P-K-S-P-S-W-W-Y-D-T-D-F-C-Q-P-I-H-G-G-R-P-I-G-I"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-N-T-M-I-T-F-L-V-L-F-V-L-T-A-A-N-G-A-P-E-A-N-E-R-K-I-P-E-A-I-H-N-E-D-Q-S-L-A-E-M-A-E-E-L-M-F-F-L-Q-Q-T-E-F-E-A-P-L-L-Q-E-E-E-E-A-E-X-A-E-X-R-N-S-R-E-R-R-C-A-M-G-D-V-P-C-T-K-G-K-T-N-C-C-K-G-Y-E-C-K-P-K-S-P-A-W-W-Y-D-T-D-F-C-Q-S-I-H-S-G-R-P-I-G-I"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-N-E-G-V-N-Q-E-Q-M-K-E-V-I-Q-N-E-F-R-E-D-F-L-N-E-M-A-P-M-S-L-L-Q-Q-L-E-A-I-E-S-T-L-L-E-K-E-A-D-R-N-S-R-Q-K-R-C-L-G-E-N-V-P-C-G-D-F-P-C-C-G-K-L-A-C-E-K-T-F-G-Y-G-W-W-Y-K-S-P-F-C-V-K-P-S-K-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-N-E-G-V-N-Q-E-Q-M-K-E-V-I-Q-N-E-F-R-E-D-F-L-N-E-M-A-A-M-S-L-L-Q-Q-L-E-A-I-E-S-T-L-L-E-K-E-A-D-R-N-S-R-Q-K-R-C-L-G-E-N-V-P-C-G-D-F-P-C-C-G-K-L-V-C-Q-K-T-F-G-Y-G-W-L-Y-K-S-P-Y-C-V-K-P-S-N-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-N-E-G-V-N-Q-E-Q-M-K-E-V-I-Q-N-E-F-R-E-D-F-L-N-E-M-A-A-M-S-L-L-Q-Q-L-E-A-I-E-S-T-L-L-E-K-E-A-D-R-N-S-R-Q-K-R-C-N-G-K-N-V-P-C-G-S-N-H-S-P-C-C-S-G-L-S-C-E-E-T-F-G-Y-G-W-L-Y-K-S-P-Y-C-V-I-P-S-N-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-K-E-G-V-N-Q-E-Q-K-K-E-V-T-Q-N-E-F-R-V-E-Y-L-N-E-M-A-A-M-S-L-L-Q-Q-L-E-A-I-E-S-A-L-F-E-K-E-A-G-R-N-S-R-Q-K-R-C-N-G-K-N-V-P-C-G-A-N-H-S-P-C-C-S-G-L-S-C-E-E-T-F-G-Y-G-W-L-Y-K-S-P-Y-C-V-I-P-S-N-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-M-K-Y-F-L-V-L-C-L-V-V-L-G-V-A-A-V-Q-A-A-A-L-E-D-E-K-F-L-N-L-A-E-S-L-A-M-P-E-E-S-R-C-K-A-R-R-Y-G-C-T-D-K-A-E-C-C-S-E-K-C-A-Y-P-A-L-T-C-A-F-N-W-S-C-E-K-V-C-A"} +{"text": "### FUNCTION Probable neurotoxin with ion channel impairing activity ### SEQUENCE -M-K-P-I-V-S-I-L-I-F-C-A-L-A-V-V-I-M-G-H-P-L-D-S-G-Y-G-I-P-H-I-V-E-K-L-P-N-G-Q-W-C-K-T-P-G-D-D-C-S-K-S-N-E-C-C-K-P-K-D-P-E-N-Y-S-G-G-C-V-A-Q-W-S-G-M-H-G-K-R-I-N-M-C-R-I-C-Y-L-E-S-S-M-C"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-M-K-L-Y-S-L-V-I-I-A-T-L-A-A-A-A-F-A-A-T-K-Q-E-I-A-A-A-A-L-S-G-M-V-H-D-F-E-Q-Y-A-K-R-A-E-G-E-E-E-P-K-R-Y-I-R-C-S-K-Q-L-G-E-K-C-D-L-N-C-E-C-C-G-A-S-A-V-C-E-D-Y-N-Y-I-C-K-E-K-V-S-D-N-P-V-L-D-W-F-G-Q-G-L-N-A-M-G-N-A-I-S-R-Y-Y-C-D-A-E"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-L-V-L-V-A-V-L-G-L-A-S-L-Y-L-L-S-Y-A-S-E-V-Q-Q-L-S-R-D-E-E-E-F-R-A-L-V-A-S-F-G-G-L-F-D-T-E-E-R-G-V-D-K-E-G-C-R-K-L-F-G-G-C-V-G-D-G-D-C-C-L-H-L-G-C-K-T-R-K-L-P-P-F-A-D-P-Y-C-A-W-D-W-T-F-G-R-K"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-N-E-G-V-N-Q-E-Q-M-K-E-V-I-Q-N-E-F-R-E-D-F-L-N-E-M-A-P-M-S-L-L-Q-Q-L-E-A-I-E-S-T-L-L-E-K-E-A-D-R-N-S-R-Q-K-R-C-L-G-E-N-V-P-C-G-D-F-P-C-C-G-K-L-V-C-Q-K-T-F-G-Y-G-W-L-Y-K-S-P-Y-C-V-K-P-S-N-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-N-E-G-V-N-Q-E-Q-M-K-E-V-I-Q-N-E-F-R-E-D-F-L-N-E-M-A-A-M-S-L-L-Q-Q-L-E-A-I-E-S-T-L-L-E-K-E-A-D-R-N-S-R-Q-K-R-C-N-G-E-N-V-P-C-G-P-N-H-S-T-C-C-S-G-L-S-C-E-E-T-F-G-Y-G-W-W-Y-D-T-P-F-C-V-K-P-S-K-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-F-L-V-L-V-L-A-T-K-F-G-D-A-N-E-G-V-N-R-E-Q-T-K-E-V-I-Q-N-E-F-R-G-D-F-L-N-E-M-A-A-M-S-L-L-Q-Q-L-E-A-I-E-S-A-L-L-E-K-E-A-D-R-N-S-R-Q-K-R-C-N-G-N-N-V-P-C-G-P-D-H-P-P-C-C-S-G-L-S-C-E-E-T-F-G-Y-G-W-W-Y-K-S-P-Y-C-V-R-P-S-K-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-L-F-M-V-L-V-A-S-F-A-F-A-V-A-L-P-S-K-K-R-E-E-T-A-A-E-N-E-L-T-G-D-L-Q-E-A-A-Q-P-M-I-Y-A-V-A-F-P-E-I-R-A-S-C-V-I-G-W-K-Q-Q-G-A-T-C-Q-R-D-C-E-C-C-G-V-A-A-T-C-I-T-G-D-S-S-T-G-F-C-G-Y-H-Q-T-P-N-A-L-G-Q-G-I-L-Y-T-A-D-T-I-K-N-G-F-S-A-I-F-C-A-G"} +{"text": "### FUNCTION Probable neurotoxin with ion channel impairing activity ### SEQUENCE -M-K-P-I-V-S-I-L-I-F-C-A-L-A-V-V-I-M-G-H-P-L-D-S-G-Y-G-I-P-H-I-V-E-K-L-P-N-G-Q-W-C-K-T-P-G-D-D-C-S-K-N-N-E-C-C-K-P-K-D-P-E-N-Y-S-S-G-C-A-S-Q-W-S-G-M-Q-G-K-R-V-N-M-C-R-I-C-Y-I-E-S-S-M-C"} +{"text": "### FUNCTION Probable toxin with unknown function ### SEQUENCE -M-N-T-A-G-R-L-L-L-L-C-L-A-L-G-L-V-F-E-S-L-G-I-P-V-A-D-D-V-E-A-V-R-D-T-D-P-D-E-K-D-P-S-V-H-N-S-L-K-A-V-Y-G-D-C-G-G-E-R-C-R-F-G-C-C-K-T-D-D-G-E-E-K-C-Q-H-F-G-C-P"} +{"text": "### FUNCTION Probable neurotoxin with ion channel impairing activity ### SEQUENCE -M-K-P-I-V-S-I-L-L-F-C-A-L-A-V-V-I-V-G-R-R-R-S-T-G-R-G-I-P-Y-V-D-E-K-L-P-N-G-Q-R-C-K-P-P-G-F-D-C-S-K-S-E-E-C-C-G-P-Q-D-T-K-N-Y-A-H-G-C-A-P-Q-W-S-G-M-W-N-K-R-V-N-E-C-Y-I-C-Y-I-E-S-S-S-C"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-M-K-L-Y-S-L-V-I-I-A-T-L-A-A-A-A-F-A-A-T-S-E-E-I-S-A-A-V-S-E-I-I-S-Q-H-Q-Q-D-L-E-R-Y-A-K-I-V-E-R-G-E-E-P-K-K-Y-I-R-C-S-K-Q-L-G-E-K-C-D-L-N-C-E-C-C-G-A-A-A-Y-C-E-D-I-V-Y-I-C-K-E-K-I-S-D-N-S-I-L-N-A-F-G-Q-A-M-T-A-M-G-N-A-V-S-R-Y-Y-C-D-A-E"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-L-V-L-V-A-V-L-G-L-A-S-L-Y-L-L-S-Y-A-S-E-V-Q-Q-I-S-R-D-E-E-D-F-R-A-L-M-A-S-F-G-G-I-F-D-T-E-E-R-G-V-D-K-E-G-C-R-K-M-F-G-D-C-W-G-D-G-D-C-C-L-H-L-G-C-K-T-R-K-L-P-P-W-T-D-K-P-Y-C-A-W-D-W-T-F-G-R-K"} +{"text": "### FUNCTION Non-toxic to mice and insects ### SEQUENCE -M-N-V-L-L-L-M-C-A-V-T-L-M-V-C-V-S-S-E-T-Y-C-G-S-Q-L-C-G-E-G-Y-C-C-T-G-G-H-F-R-R-Q-C-R-P-L-A-D-E-G-Q-Q-C-E-K-E-N-K-Y-N-D-Y-K-L-G-C-P-C-K-G-G-M-I-C-S-D-I-K-Y-C-Q-K-L"} +{"text": "### FUNCTION Probable toxin ### SEQUENCE -M-R-T-S-G-R-L-L-L-L-C-L-A-V-G-L-L-L-E-S-Q-A-H-P-N-A-D-A-G-D-A-T-R-D-V-G-S-D-R-T-S-V-E-L-S-K-M-L-K-G-W-Q-A-E-K-G-Q-R-K-A-S-A-P-K-K-F-Y-V-Y-P-P-V-R-R-S-F-Y"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-N-E-G-V-N-Q-E-Q-M-K-E-V-I-Q-N-E-F-R-E-D-F-L-N-E-M-A-A-M-S-L-L-Q-Q-L-E-A-I-E-S-T-L-L-E-K-E-A-D-R-N-S-R-Q-K-R-C-L-G-E-N-V-P-C-G-D-F-P-C-C-G-K-L-A-C-E-K-T-F-G-Y-G-W-W-Y-K-S-P-F-C-V-K-P-S-K-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-N-E-G-V-N-Q-E-Q-M-K-E-V-I-Q-N-E-F-R-E-D-F-L-N-E-M-A-P-M-S-L-L-Q-Q-L-E-A-I-E-S-T-L-L-E-K-E-A-D-R-N-S-R-Q-K-R-C-N-G-E-N-V-P-C-G-P-N-H-S-T-C-C-S-G-L-S-C-E-E-T-F-G-Y-G-W-W-Y-D-T-P-F-C-V-K-P-S-K-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-I-I-V-F-L-S-L-L-V-L-A-T-K-F-G-D-A-N-E-G-V-N-Q-E-Q-M-K-E-V-I-Q-N-E-F-R-E-D-F-L-N-E-M-A-A-M-S-L-L-Q-Q-L-E-A-I-E-S-T-L-L-E-K-E-A-D-R-N-S-R-Q-K-R-C-N-G-N-N-V-P-C-G-P-D-H-P-P-C-C-S-G-L-S-C-E-K-T-F-G-Y-G-W-W-Y-K-S-P-Y-C-V-R-P-S-K-G"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-L-F-M-V-L-V-A-S-F-A-F-A-V-A-L-P-S-K-K-R-E-E-T-A-E-N-E-L-T-G-D-L-Q-E-A-A-Q-P-M-I-Y-A-V-A-F-P-E-I-R-A-S-C-V-I-G-W-K-Q-Q-G-A-K-C-E-R-D-C-E-C-C-G-V-A-A-T-C-I-T-R-S-T-N-S-L-P-G-F-C-G-Y-R-Q-T-P-N-V-L-G-Q-G-L-L-Y-T-A-D-T-I-S-N-G-L-S-A-I-F-C-A-A"} +{"text": "### FUNCTION Probable neurotoxin with ion channel impairing activity ### SEQUENCE -M-K-T-I-F-A-L-V-F-C-C-A-I-A-V-V-V-L-G-F-G-E-N-E-G-S-T-I-D-H-D-Q-N-N-C-K-G-P-G-S-R-C-S-N-K-N-E-C-C-K-P-K-D-M-E-T-Y-T-Y-Y-C-G-S-R-W-D-S-S-S-G-D-F-V-R-K-C-V-I-C-N-R-E-S-S-M-C"} +{"text": "### FUNCTION Probable neurotoxin with ion channel impairing activity ### SEQUENCE -M-K-P-T-I-S-I-L-I-F-F-A-L-A-V-A-I-M-G-H-R-L-N-S-G-Y-G-I-P-H-I-V-E-K-L-P-N-G-Q-W-C-R-T-P-G-D-D-C-S-E-S-K-Q-C-C-K-P-E-D-T-A-T-Y-A-H-G-C-S-Q-Q-W-S-G-Q-R-G-E-L-V-K-M-C-Y-I-C-N-K-E-S-S-M-C"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-M-K-L-Y-S-L-V-I-I-A-T-L-A-A-A-A-F-A-A-T-S-E-E-I-S-A-A-V-S-E-I-I-S-Q-H-Q-E-D-L-E-R-Y-A-K-I-V-E-R-G-E-E-P-K-K-Y-I-R-C-S-K-Q-L-G-Q-S-C-Y-L-N-C-E-C-C-G-A-S-A-V-C-E-D-I-K-Y-I-C-K-D-K-V-S-D-N-S-I-L-D-A-M-G-K-A-W-N-A-V-G-N-S-I-S-R-Y-Y-C-S-A-E"} +{"text": "### FUNCTION Ion channel inhibitor ### SEQUENCE -M-K-T-L-V-L-V-A-V-L-G-V-A-S-L-Y-L-L-S-S-A-S-E-V-Q-Q-L-S-P-A-E-E-E-F-R-A-F-V-S-T-F-G-G-L-F-E-T-E-E-R-G-V-D-S-E-D-C-R-A-M-F-G-G-C-G-E-D-N-D-C-C-L-H-L-G-C-K-T-T-K-L-P-P-F-A-N-P-Y-C-A-W-D-G-T-T-G-R-K"} +{"text": "### FUNCTION Part of the gene cluster that mediates the biosynthesis of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin ### SEQUENCE -M-E-P-Q-T-K-D-P-D-P-L-P-R-L-V-H-I-G-E-I-Q-F-N-L-G-E-V-T-T-G-G-V-T-P-R-G-T-F-I-F-C-P-I-T-G-G-H-F-T-T-V-F-P-L-P-D-G-F-G-I-H-S-E-A-I-E-G-L-R-A-E-V-L-P-G-G-G-D-Y-P-L-I-H-N-N-E-L-A-E-L-N-V-S-V-V-A-K-G-L-N-N-D-H-I-F-R-I-T-S-F-G-I-C-E-W-N-K-L-I-F-D-M-M-G-Q-T-A-A-A-R-S-T-E-M-G-E-I-N-A-W-Q-V-F-R-I-N-T-D-S-P-E-Y-A-W-L-N-W-A-C-I-I-G-Q-E-R-L-I-Y-E-D-S-R-M-A-K-T-H-M-K-L-F-Q-F-L-V-K"} +{"text": "### FUNCTION Highly reducing polyketide synthase ### SEQUENCE -M-S-A-P-K-G-P-I-T-K-F-P-A-E-G-L-R-H-A-R-R-F-I-T-T-H-N-K-E-G-K-G-V-F-A-V-D-D-D-G-D-H-H-R-I-M-V-D-G-L-A-V-A-N-I-I-Y-S-T-S-G-N-P-V-D-M-N-D-D-N-D-L-V-Y-A-R-D-N-E-V-R-R-F-A-G-Q-I-N-L-F-V"} +{"text": "### FUNCTION UstYa family oxidase, part of the gene cluster that mediates the biosynthesis of the secondary metabolite victorin, the molecular basis for Victoria blight of oats ### SEQUENCE -M-L-T-K-S-R-L-Q-V-F-H-E-L-H-C-L-N-F-L-R-K-L-I-Y-P-D-V-Y-G-K-I-D-Y-K-G-Q-I-H-A-N-H-C-I-D-H-I-R-R-I-A-E-C-G-S-N-A-T-P-V-V-Y-T-G-Y-K-N-G-N-L-Y-S-E-P-E-T-Y-T-C-R-N-F-T-L-I-R-Q-W-A-E-M-K-K-I-Q-N-T-Q"} +{"text": "### FUNCTION UstYa family oxidase, part of the gene cluster that mediates the biosynthesis of the secondary metabolite victorin, the molecular basis for Victoria blight of oats ### SEQUENCE -M-D-L-Y-I-S-N-Y-T-S-D-D-D-M-A-I-L-R-R-R-W-I-E-L-L-P-L-V-V-G-D-I-V-H-V-E-N-P-E-G-Y-S-Y-L-L-D-P-I-I-P-G-P-G-Y-V-V-T-W-Y-H-Q-L-H-C-L-F-F-L-M-S-E-Y-D-R-L-L-R-H-G-P-N-G-K-E-R-S-I-P-A-G-S-S-S-I-H-T-R-H-C-F-E-I-L-R-H-S-I-L-C-H-L-D-M-T-L-E-G-G-S-A-P-F-F-N-G-T-T-G-F-G-H-A-H-V-C-Q-N-R-Q-E-A-I-D-W-M-E-K-N-R-A-N-D-N-R-M-I-I-R-A"} +{"text": "### FUNCTION Part of the gene cluster that mediates the biosynthesis of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties ### SEQUENCE -M-A-S-E-L-K-E-Y-L-V-I-I-P-D-L-P-D-V-L-A-K-R-Q-V-L-L-K-P-H-N-Q-D-A-A-P-L-V-K-A-G-R-V-P-F-F-G-S-T-L-A-H-H-S-A-E-G-Q-Q-V-A-E-N-G-T-V-M-I-I-K-A-E-S-E-E-E-I-K-E-I-I-R-K-D-I-F-T-I-E-G-V-W-D-F-G-R-L-S-I-W-P-F-K-S-K"} +{"text": "### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations ### SEQUENCE -M-S-W-Q-A-Y-V-D-D-H-L-M-C-E-I-E-G-T-N-N-H-L-T-A-A-A-I-L-G-V-D-G-S-V-W-A-Q-S-A-N-F-P-Q-F-K-P-D-E-I-S-A-V-V-K-E-F-D-E-A-G-T-L-A-P-T-G-L-H-L-G-G-T-K-Y-M-V-I-Q-S-E-A-G-Q-V-I-R-G-K-K-G-P-G-G-I-C-V-K-K-T-G-Q-A-L-I-F-G-I-Y-D-E-P-V-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-I-E-Q-G-L"} +{"text": "### FUNCTION Its target is unknown, but this toxin may modulate voltage-activated calcium channels ### SEQUENCE -M-G-K-L-T-I-L-V-L-V-A-A-V-L-L-S-T-Q-A-M-V-Q-G-D-G-D-Q-P-A-A-R-N-A-V-P-R-D-D-N-P-D-G-P-S-A-K-F-M-N-V-Q-R-R-S-G-C-P-W-E-P-W-C-G"} +{"text": "### FUNCTION Does not show activity on all the human nAChR subtypes studied ### SEQUENCE -M-G-M-R-M-M-F-T-V-F-L-L-V-V-L-A-T-T-V-V-S-F-T-S-R-R-G-P-K-S-R-R-G-E-P-V-P-T-T-V-I-N-Y-G-E-C-C-K-D-P-S-C-W-V-K-V-K-D-F-Q-C-P-G-A-S-P-P-N"} +{"text": "### FUNCTION Moderately activates human somatostatin receptors with a preferential activation of SSTR1 and SSTR4 In vivo, does not cause behavioral changes in mice within a few minutes of intracranial injection, but causes a progressive loss of movement thereafter Four to five hours after injection, mice recover, even with the highest dose tested Shows antinociception and antihyperalgesia activities in two mouse models of acute pain, most probably by acting outside the central nervous system ### SEQUENCE -M-Q-T-A-Y-W-V-M-L-M-M-M-V-C-I-T-A-P-L-P-E-G-G-K-P-N-S-G-I-R-G-L-V-P-N-D-L-T-P-Q-H-T-L-R-S-L-I-S-R-R-Q-T-D-V-L-L-D-A-T-L-L-T-T-P-A-P-E-Q-R-L-F-C-F-W-K-S-C-T-W-R-P-Y-P-W-R-R-R-D-L-N-G-K-R"} +{"text": "### FUNCTION Transcriptional regulator that may regulate the expression of the satratoxin biosynthesis SC2 cluster, one of the 3 clusters involved in the biosynthesis of satratoxins, trichothecene mycotoxins that are associated with human food poisonings ### SEQUENCE -M-T-T-P-P-G-W-K-V-S-G-Q-N-E-I-S-R-P-F-D-I-L-E-A-W-F-H-R-I-V-G-G-G-N-L-T-R-E-R-D-S-F-G-S-N-Y-V-V-K-L-G-F-P-G-S-V-A-D-P-I-P-Y-L-R-R-A-W-L-V-T-R-Y-L-H-P-Q-L-G-A-T-Y-S-S-K-S-L-D-D-L-R-Y-I-I-R-P-L-D-E-Q-I-W-L-Q-T-T-F-F-V-E-Q-G-P-S-A-T-Y-S-S-A-E-D-A-V-S-K-Y-L-S-K-S-T-T-T-A-H-W-I-P-A-T-S-E-F-M-I-S-P-T-A-S-S-P-L"} +{"text": "### FUNCTION Immunity protein that plays a role in preventing early activation of toxin Tas1 ### SEQUENCE -M-A-I-E-K-G-E-A-F-A-R-R-D-I-Y-I-D-Y-D-F-E-D-V-T-Y-R-W-D-H-R-Q-G-T-I-H-V-R-F-Y-G-E-A-E-S-P-E-P-V-E-H-D-N-R-L-F-N-D-A-L-R-F-G-R-E-I-T-R-E-E-Y-E-T-G-F-P-K-G"} +{"text": "### FUNCTION Antitoxin for tuberculosis necrotizing toxin glycohydrolase activity of TNT and protects Mbovis from self-poisoning ### SEQUENCE -M-T-I-G-V-D-L-S-T-D-L-Q-D-W-I-R-L-S-G-M-N-M-I-Q-G-S-E-T-N-D-G-R-T-I-L-W-N-K-G-G-E-V-R-Y-F-I-D-R-L-A-G-W-Y-V-I-T-S-S-D-R-M-S-R-E-G-Y-E-F-A-A-A-S-M-S-V-I-E-K-Y-L-Y-G-Y-F-G-G-S-V-R-S-E-R-E-L-P-A-I-R-A-P-F-Q-P-E-E-L-M-P-E-Y-S-I-G-T-M-T-F-A-G-R-Q-R-D-T-L-I-D-S-S-G-T-V-V-A-I-T-A-A-D-R-L-V-E-L-S-H-Y-L-D-V-S-V-N-V-I-K-D-S-F-L-D-S-E-G-K-P-L-F-T-L-W-K-D-Y-K-G"} +{"text": "### FUNCTION Major early protein present in virus factories The presence of BEN domains suggests a possible role in organization of viral DNA during replication or transcription ### SEQUENCE -M-I-N-D-D-S-F-T-L-K-R-K-Y-Q-I-D-S-A-E-S-T-M-K-M-D-K-T-M-T-K-F-Q-N-R-V-K-M-V-K-E-I-N-Q-T-I-R-A-A-Q-T-H-Y-E-T-L-K-L-G-Y-I-K-F-K-G-M-I-R-T-T-T-L-E-D-I-A-P-S-I-P-N-N-Q-K-T-Y-K-L-F-S-D-I-S-V-I-G-K-A-S-Q-N-P-S-K-M-I-Y-A-R-C-F-T-C-F-P-I-C-L-E-M-T-I-D-S-F-V-I-E-C-I-Q-H-C-S"} +{"text": "### FUNCTION Contributes to virulence by binding to the host IKBKB subunit of the IKK complex and preventing host NF-kappa-B activation in response to pro-inflammatory stimuli such as TNF-alpha or IL1B Mechanistically, sterically hinders the direct contact between the kinase domains of IKBKB in the IKK complex containing IKBKB, CHUK/IKKA and NEMO ### SEQUENCE -M-T-A-N-F-S-T-H-V-F-S-P-Q-H-C-G-C-D-R-L-T-S-I-D-D-V-R-Q-C-L-T-E-Y-I-Y-W-S-S-Y-A-Y-R-N-R-Q-C-A-G-Q-L-Y-D-T-L-L-S-F-K-D-D-A-E-S-V-F-I-D-V-R-E-L-V-K-N-M-P-W-D-N-V-K-D-C-T-E-I-I-R-C-Y-I-P-D-E-Q-K-T-I-R-E-I-S-A-I-I-G-L-C-A-Y-A-A-T-Y-W-G-G-E-D-H-P-T-S-N-S-L-N-A-L-F-V-M-L-E-M-L-N-Y-M-D-Y-T-I-I-F-W-R-M-N"} +{"text": "### FUNCTION Proetin of unknown function whose overexpression causes growth inhibition Overexpression increases the expression of ergosterol synthesis genes ### SEQUENCE -M-N-V-R-G-N-Q-C-I-M-S-I-R-V-F-L-K-A-G-E-S-S-L-S-F-A-I-K-W-L-K-R-F-E-A-T-T-K-K-N-Q-Y-I-Q-N-G-W-P-L-K-D-G-N-K-K-R-K"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-A-I-F-D-S-V-S-N-M-E-E-Q-I-G-E-L-Y-Q-Q-L-G-D-L-K-T-N-L-G-E-M-L-E-E-N-N-R-L-N-L-E-N-E-H-L-R-R-R-L-S-L-T-D-E-G-T-L-E-P-V-A-E-E-E-A-V-H-G-V-M-A-P-N-R-K-E-A-M-Q-Q-M-I-E-L-G-E-G-Y-D-N-L-V-Q-L-Y-K-E-G-F-H-V-C-N-V-H-F-G-S-P-R-G-N-D-E-D-C-L-F-C-L-S-L-L-N-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-M-L-I-G-G-I-R-L-Y-Q-K-Y-I-S-R-F-T-P-A-T-C-R-F-Y-P-T-C-S-A-Y-G-I-E-A-I-E-T-H-G-A-L-K-G-S-Y-L-A-I-K-R-I-S-K-C-H-P-F-H-K-G-G-L-D-F-V-P-P-K-K-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-F-E-K-T-N-R-M-N-L-L-F-D-F-Y-Q-E-L-L-T-T-K-Q-K-A-Y-V-S-F-Y-Y-L-D-D-Y-S-L-G-E-I-A-E-E-F-E-V-S-R-Q-A-I-Y-D-N-I-K-R-T-E-E-S-L-E-K-Y-E-E-K-L-G-M-L-K-K-Y-Q-Q-R-E-K-L-F-S-E-L-E-A-Q-L-T-K-K-N-F-L-D-E-Q-V-K-D-T-L-E-Q-L-K-N-I-D"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-Q-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-S-V-S-K-E-A-W-Q-G-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-D-G-A-D-Q-A-S-G-Y-V-P-P-T-E-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-V-L-I-A-L-L-R-F-Y-K-V-A-V-S-P-M-L-G-N-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-V-R-R-V-C-R-C-H-P-F-S-A-G-G-V-D-L-V-P-P-P-N-S-D-T-R-A-R-G-E-A-D-A-R-S-H-R-L"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-S-D-Q-V-L-S-A-L-E-H-F-F-L-R-W-Q-R-D-G-E-A-R-R-G-L-P-L-C-E-W-E-A-D-W-R-S-P-C-E-L-D-E-P-K-E-G-R-V-A-W-R-P-H-R-R-A-E-P-A-D-F-T-A-M-N-E-A-L-E-L-T-L-H-P-A-A-Q-A-L-F-G-G-W-F-S-R-P-V-P-C-L-Y-K-G-L-R-L-E-F-V-L-P-W-N-E-A-D-L-D-L-L-K-E-N-L-I-G-H-L-L-M-L-R-K-L-K-R-S-P-S-L-F-I-A-T-T-R-N-E-M-T-L-V-S-L-D-N-E-S-G-Q-V-W-L-E-W-L-D-S-G-R-R-L-V-L-A-P-S-L-P-A-F-L-E-R-L-E-T-L-P-Q"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-Q-R-L-K-K-E-G-P-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-E-A-W-T-E-W-Q-K-K-Q-V-M-L-I-N-E-K-K-L-N-M-M-N-L-E-H-R-Q-L-L-E-K-E-M-V-N-Y-L-F-E-A-G-E-V-A-I-D-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-L-Q-W-L-A-T-T-F-I-R-G-Y-Q-I-F-I-S-P-L-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-K-V-H-G-T-A-K-G-C-W-F-A-L-K-R-I-L-K-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-V-S-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-T-S-F-L-F-E-G-K-D-V-E-I-E-G-F-V-P-E-K-G-Q-E"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-N-T-P-A-A-R-P-D-R-Y-Q-S-F-A-H-I-P-C-D-A-M-A-L-K-L-L-T-H-L-E-Q-L-L-Q-A-E-D-T-L-E-P-F-W-Q-L-F-L-Q-K-A-A-I-A-K-Q-P-Q-P-G-Q-A-D-A-L-K-L-I-C-S-N-S-Y-Y-I-F-D-L-F-A-A-Q-Q-D-Q-A-G-E-A-M-M-D-E-L-E-Y-Q-C-C"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-R-L-L-V-L-L-V-R-F-Y-Q-L-F-I-S-P-V-L-P-P-S-C-R-H-S-P-T-C-S-Q-Y-A-I-E-A-L-Q-K-H-G-A-I-K-G-S-W-L-A-F-R-R-V-L-R-C-N-P-W-H-P-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-R-S-I-F-L-G-L-I-R-F-Y-Q-I-V-L-S-P-L-K-G-P-R-C-R-F-L-P-T-C-S-Q-Y-A-Y-E-A-I-E-R-Y-G-I-W-R-G-L-F-L-G-G-K-R-L-L-R-C-H-P-F-H-A-G-G-Y-D-P-V-P-R-P-S-A-N-N-H-P-S-R"} +{"text": "### FUNCTION Targets the host DNA sliding clamp and inhibits host DNA replication ### SEQUENCE -M-E-Q-L-N-Y-G-Y-K-I-K-R-N-Q-V-R-G-S-W-L-F-L-V-Y-G-K-P-I-Y-E-L-H-R-G-E-K-S-K-T-Y-Y-V-T-H-I-A-T-G-K-T-P-A-C-A-G-L-L-R-D-A-I-M-K-A-C-M-L-E-G-L-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-I-I-L-I-H-I-I-K-F-Y-R-K-Y-I-S-P-L-K-K-P-C-C-R-F-Y-P-T-C-S-K-Y-A-L-D-A-I-N-K-Y-G-A-F-K-G-S-I-M-A-I-K-R-I-L-R-C-H-P-F-N-P-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-I-R-K-I-S-A-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-T-G-E-F-K-D-I-A-H-P-I-N-T-E-T-R-Q-K-I-Q-K-A-I-L-D-E-Y-E-V-V-K-N-E-T-T-N-N-E-N-G-E-E-I-T-S-E-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-D-R-I-K-I-S-I-L-M-D-Y-Y-R-E-L-L-T-E-K-Q-K-Y-V-M-E-L-Y-F-N-Q-D-L-S-L-A-E-I-S-E-L-T-N-T-S-R-Q-A-I-Y-D-I-I-K-R-C-N-K-L-L-V-D-Y-E-K-K-L-N-L-A-R-K-N-K-E-L-I-K-A-K-Q-I-I-I-E-K-I-N-D-L-E-Y-S-N-N-K-N-D-F-K-N-S-L-E-D-I-K-N-T-I-V-Q-Y-I"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-F-F-K-K-I-T-L-I-P-F-V-M-L-I-N-L-Y-R-Y-C-I-S-P-F-I-P-A-R-C-R-Y-Y-P-T-C-S-E-Y-A-L-E-A-L-K-T-H-G-I-L-K-G-L-Y-L-T-T-R-R-L-L-R-C-H-P-L-S-K-R-D-Y-Y-D-P-V-P-C-K-N-K-K-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-K-V-F-C-K-K-Y-H-Q-E-L-D-A-I-P-F-Q-P-L-P-G-E-L-G-K-K-I-H-N-E-I-S-N-K-A-W-Q-A-W-L-A-H-Q-T-I-L-I-N-E-Y-R-L-N-L-I-E-P-K-A-K-E-F-L-K-E-E-M-H-K-F-L-F-E-G-K-E-E-K-P-E-Q-F-S-E-I"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-D-S-T-G-R-N-L-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-Q-K-L-G-I-P-A-I-R-I-P-L-H-G-R-I-E-V-D-H-P-Y-V-L-L-L-P-T-Y-G-G-G-R-A-T-P-D-L-N-A-G-G-Y-V-P-K-Q-V-I-A-F-L-N-N-E-H-N-R-S-L-I-R-G-V-I-A-A-G-N-N-N-F-G-A-E-F-A-Y-A-G-N-V-V-S-R-K-C-G-V-P-Y-L-Y-R-F-E-L-M-G-T-Q-D-D-V-D-A-V-R-A-G-L-A-E-F-W-K-E-Q-T-C-H-Q-P-S-L-Q-S-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-G-P-A-R-S-G-A-A-I-R-G-A-G-R-T-V-A-R-G-L-I-F-L-I-Q-L-Y-R-H-M-V-S-P-L-R-P-A-T-C-R-F-V-P-T-C-S-Q-Y-A-V-D-A-L-D-E-Y-G-L-I-R-G-S-W-L-A-A-A-R-L-T-K-C-G-P-W-H-Q-G-G-W-D-P-I-P-E-R-P-G-C-R-V-N-C-Q-D-A-S-D-A-W-A-V-R-A-T-R-G-E-S-G-S-L-V"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-D-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-A-Q-L-L-V-I-V-K-I-L-P-K-G-T-E-V-D-L-D-E-M-M-E-G-L-K-G-G-L-K-G-G-I-V-L-R-R-Y-A-K-E-P-L-A-F-G-L-H-F-V-K-A-E-F-I-L-E-D-K-E-G-Q-N-D-A-L-E-A-T-V-R-S-A-K-G-V-S-E-Y-E-V-L-N-M-S-R-M-S-V-D-M-K"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-S-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-S-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-Q-K-M-T-E-T-D-R-Y-V-T-F-K-G-I-D-G-D-G-N-A-R-R-L-V-A-M-L-R-R-H-I-D-D-P-A-K-T-N-L-F-W-E-K-F-K-E-K-L-E-L-A-E-S-P-D-T-N-N-T-R-R-L-D-E-L-F-L-I-H-S-Y-I-N-N-I-Y-D-L-L-E-E-H-G-D-Q-E-A-L-T-L-L-H-Q-I-E-V-E-S-C"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-P-F-A-H-L-L-A-L-P-V-R-A-Y-R-L-V-A-S-P-W-V-G-H-G-C-R-F-Q-P-T-C-S-A-Y-A-L-E-A-L-E-R-H-G-A-A-K-G-G-W-L-A-A-R-R-V-C-R-C-H-P-W-G-G-H-G-F-D-P-V-P-G-S-E-A-P-R-Q-D"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-I-S-V-W-I-R-V-L-G-A-L-L-L-A-S-V-A-Q-A-Q-F-Q-F-F-E-Q-M-F-G-G-G-H-Q-E-H-H-Q-Q-G-S-Q-N-S-A-S-D-S-S-R-Y-Q-Q-L-W-E-A-T-N-C-N-K-Y-L-C-P-G-T-L-A-C-V-D-F-P-H-H-C-P-C-E-H-P-N-V-E-D-K-V-E-L-G-E-G-S-A-V-C-I-S-K-G-G-Y-K-P-G-E-A-A-R-K-I-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-L-S-S-W-V-R-C-L-G-A-L-L-L-L-A-S-V-A-Q-A-Q-F-Q-F-F-E-H-M-F-G-G-G-H-Q-E-H-H-Q-Q-N-T-Q-N-S-A-S-D-S-A-R-Y-Q-Q-L-W-E-G-T-N-C-N-K-Y-L-C-P-G-T-L-A-C-V-D-F-P-H-H-C-P-C-A-H-P-S-V-E-D-K-V-E-L-G-E-G-S-A-V-C-I-S-K-G-G-Y-K-P-G-E-A-A-R-K-I-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-Q-N-V-S-T-A-L-K-S-F-T-Q-R-Y-I-D-L-W-Q-Q-Q-T-G-R-P-P-A-S-E-E-L-Y-G-V-P-S-P-C-N-I-E-T-Q-D-N-Q-V-F-W-L-P-Q-P-F-V-G-E-A-N-L-A-N-V-E-R-A-L-E-I-Q-L-H-P-D-I-H-E-F-Y-T-Q-Q-Y-A-G-D-M-K-A-D-L-G-D-H-R-F-T-L-L-Q-V-W-S-E-D-D-F-I-R-L-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-L-F-L-A-T-T-E-S-E-M-T-M-A-S-L-C-N-V-S-G-N-M-V-L-E-E-F-G-S-G-K-R-T-L-L-A-S-T-L-A-H-F-L-D-A-L-R-P-V-F-P-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-K-K-E-A-E-G-Q-D-F-Q-L-Y-P-G-E-I-G-K-R-I-Y-N-E-I-S-K-E-A-W-S-Q-W-V-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-V-E-D-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-Q-D-V-H-I-E-G-Y-T-P-P-S-Q"} +{"text": "### FUNCTION Functions as a specific chaperone for YopT ### SEQUENCE -M-Q-T-T-F-T-E-L-M-Q-Q-L-F-L-K-L-G-L-N-H-Q-V-N-E-N-D-V-Y-T-F-E-V-D-G-H-I-Q-V-L-I-A-C-Y-H-Q-Q-W-V-Q-L-F-S-E-L-G-A-D-L-P-T-N-D-N-L-F-G-E-H-W-P-A-H-V-Q-G-R-L-D-G-K-P-I-L-W-S-Q-Q-S-L-V-G-L-D-I-D-E-M-Q-A-W-L-E-R-F-I-D-D-I-E-Q-R-K-E-S-Q-N-T-K-F-Q-P-N-S-T-S-P-I-L-F-I"} +{"text": "### FUNCTION Involved in the down-regulation of lcrGVH transcription in the presence or absence of calcium and is necessary for lcrG protein expression in the absence of calcium Plays an important role in the regulation of the low-calcium response ### SEQUENCE -M-M-E-D-P-L-I-P-W-L-T-E-H-G-L-V-C-H-P-H-T-L-S-G-A-P-I-S-L-G-S-A-F-Q-L-A-G-L-K-L-A-W-R-V-E-I-E-Q-R-R-V-W-I-V-L-I-Q-R-V-E-Q-R-R-G-L-K-N-P-F-A-A-L-Y-M-L-A-N-A-A-R-A-V-L-G-P-D-Y-Y-L-Y-G-N-V-D-V-L-A-G-S-S-L-S-T-Q-R-L-A-H-F-Y-R-R-W-T-G-A-K-E-L-S-T-G-W-F-S-L-K-V-S-Q-V-I-T-L-S-N-M-K-K-R-Q-N-N-G-F-A"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-A-R-V-T-S-V-T-L-G-E-H-L-T-G-F-V-G-E-M-I-Q-S-G-R-Y-G-N-I-S-E-V-L-R-D-A-L-R-L-M-E-A-R-E-Q-R-V-Q-H-V-R-D-M-V-L-A-G-T-N-A-P-V-S-H-R-L-M-D-E-I-F-S-A-A-V-K-D-T-S-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-N-C-I-K-L-G-R-E-A-E-G-L-D-L-P-P-V-P-G-E-L-G-K-R-I-Y-E-S-V-S-K-E-A-W-Q-Q-W-V-K-Y-Q-T-M-L-I-N-E-N-R-L-N-L-M-D-P-R-A-R-K-Y-L-S-E-Q-M-E-K-H-F-F-E-G-G-A-D-A-I-G-G-F-V-P-P-A-Q"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-V-L-I-V-L-L-R-F-Y-R-Y-A-I-S-P-M-L-G-R-N-C-R-F-H-P-S-C-S-E-Y-A-I-E-A-V-Q-R-H-G-A-V-R-G-A-W-L-A-A-R-R-V-A-R-C-H-P-F-H-P-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-D-I-A-G-R-S-L-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-Q-K-L-G-I-P-A-T-R-I-P-L-H-G-R-I-E-V-D-E-P-Y-V-L-I-L-P-T-Y-G-G-G-R-A-N-P-G-L-D-A-G-G-Y-V-P-K-Q-V-I-A-F-L-N-N-D-H-N-R-A-Q-L-R-G-V-I-A-A-G-N-T-N-F-G-A-E-F-C-Y-A-G-D-V-V-S-R-K-C-S-V-P-Y-L-Y-R-F-E-L-M-G-T-E-D-D-V-A-A-V-R-T-G-L-A-E-F-W-K-E-Q-T-C-H-Q-P-S-L-Q-S-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-F-L-L-S-K-L-L-L-G-L-I-R-F-Y-Q-Y-C-I-S-P-L-I-P-P-R-C-R-Y-T-P-T-C-S-Q-Y-A-V-E-A-V-K-K-Y-G-A-F-K-G-G-R-L-A-I-K-R-I-A-R-C-H-P-L-G-G-H-G-H-D-P-V-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-F-C-V-K-L-N-K-E-A-E-G-M-K-F-P-P-L-P-N-E-L-G-K-R-I-F-E-N-V-S-Q-E-A-W-A-A-W-T-R-H-Q-T-M-L-I-N-E-N-R-L-S-L-A-D-P-R-A-R-E-Y-L-A-Q-Q-M-E-Q-Y-F-F-G-D-G-A-D-A-V-Q-G-Y-V-P-Q"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-N-I-T-D-V-R-I-R-R-V-D-N-K-N-P-G-S-K-L-L-A-Y-V-T-V-T-F-D-D-C-L-V-L-H-N-I-R-V-I-R-G-Q-K-G-V-F-I-V-M-P-N-R-R-T-K-V-G-E-Y-K-D-I-V-H-P-I-N-Q-N-F-R-E-I-L-Q-S-A-I-F-K-E-Y-V-K-E-N-P-S-S-L-E-L-E-L-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-T-S-F-L-F-E-G-K-D-V-E-I-E-G-F-V-P-E-K-D-Q-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-L-Q-W-L-A-T-T-L-I-R-G-Y-Q-I-F-I-S-P-I-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-K-V-H-G-T-A-K-G-C-W-F-A-L-K-R-I-L-K-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-F-Q-W-L-A-T-K-L-I-R-G-Y-Q-I-F-I-S-P-I-L-G-P-K-C-R-F-Q-P-T-C-S-H-Y-A-I-E-A-I-Q-L-H-G-V-I-K-G-S-W-F-A-A-K-R-I-L-K-C-H-P-L-H-P-G-G-N-D-P-V-P-P-K-K-D-R-C-N-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-Q-C-V-Y-L-G-K-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-T-I-S-K-E-A-W-G-E-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-M-D-H-R-K-L-L-E-E-Q-M-Q-L-F-L-F-E-G-K-D-V-Q-I-E-G-Y-V-P-P-K-P-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-F-C-S-Y-L-K-K-E-A-P-G-L-A-F-Q-L-I-P-G-A-L-G-K-R-I-F-D-N-I-S-Q-E-A-W-S-E-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-K-L-M-N-A-E-D-R-K-I-I-E-D-A-M-I-G-Y-L-F-E-N-K-E-V-D-I-E-G-Y-T-P-E-K"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-N-H-T-T-Q-T-Q-L-F-D-F-F-E-R-F-K-A-H-W-Q-T-Q-K-K-S-L-P-Q-A-I-F-E-P-Q-W-I-S-P-C-Q-I-G-E-V-E-N-Q-L-I-F-W-S-P-I-K-R-E-P-A-L-D-M-S-N-I-E-Q-A-L-D-I-K-L-H-P-S-I-V-D-F-F-C-S-A-Y-S-A-G-L-P-A-V-Y-Q-D-H-P-I-E-L-I-Q-A-W-N-D-E-D-F-N-L-L-Q-E-N-M-L-A-H-F-M-M-Q-K-R-L-K-Q-P-A-S-M-F-I-A-S-C-S-D-E-M-Q-I-V-S-V-L-N-A-T-G-E-V-Q-L-E-T-L-G-K-G-Q-E-A-I-L-A-E-N-L-A-D-F-L-A-T-L-T-P-V-I-I-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-N-L-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-E-K-L-G-L-P-A-T-R-I-P-I-H-G-R-I-Q-V-D-E-P-Y-V-L-V-L-P-T-Y-G-G-G-H-A-N-G-P-D-P-D-R-G-G-Y-V-P-K-Q-V-I-A-F-L-N-D-E-H-N-R-S-L-I-R-G-V-I-A-A-G-N-T-N-F-G-A-E-F-G-Y-A-G-V-I-V-S-R-K-C-G-V-P-F-L-Y-R-F-E-L-M-G-T-T-D-D-V-F-A-V-R-Q-G-L-T-D-F-W-A-D-A-R-K-D-Q-T-C-H-Q-P-S-Q-L-Q-N-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-Q-C-I-K-L-G-K-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-K-R-I-F-E-N-V-S-K-E-A-W-A-G-W-L-K-H-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-Q-Y-L-A-R-Q-M-E-Q-H-F-F-G-G-G-A-D-A-A-A-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-R-K-Y-Q-K-E-L-E-G-L-A-M-P-P-M-P-G-P-K-G-Q-D-I-Y-E-N-V-S-K-L-A-W-E-E-W-Q-N-Q-Q-T-M-L-I-N-E-K-H-L-N-L-M-D-V-N-N-R-K-Y-L-Q-A-Q-M-E-R-F-F-N-N-E-P-F-D-Q-A-E-G-Y-V-P-P-E-K"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-G-N-I-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-E-K-L-E-L-P-A-T-R-I-P-I-L-G-R-I-Q-D-P-D-F-V-R-E-P-Y-V-L-V-L-P-T-Y-G-G-G-H-A-N-G-P-D-P-D-A-G-G-Y-V-P-K-Q-V-I-A-F-L-N-N-E-H-N-R-S-L-I-R-G-V-I-A-A-G-N-T-N-F-G-A-E-F-G-Y-A-G-D-V-V-S-R-K-C-G-V-P-Y-L-Y-R-F-E-L-M-G-T-T-D-D-V-L-A-V-R-A-G-L-E-N-F-W-K-E-Q-T-C-H-P-P-S-Q-L-Q-S-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-E-Q-H-P-K-Q-G-K-I-Q-T-R-N-Y-A-G-P-W-R-K-T-P-G-R-L-L-G-T-G-L-I-R-L-Y-Q-I-T-L-S-N-F-I-G-N-Q-C-R-Y-M-P-T-C-S-E-Y-T-Y-E-A-I-A-R-H-G-L-W-A-G-A-W-M-G-L-F-R-I-V-C-C-N-P-F-G-T-H-G-F-D-P-V-P-T-S-L-G-S-S-Y-Y-F-Y-K-P-W-C-Y-R-K-I-S-T-K-H-N-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-H-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-L-Y-E-S-V-S-K-Q-A-W-Q-D-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-A-Q-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-V-L-I-A-L-L-R-F-Y-K-L-A-V-S-P-L-L-G-S-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-A-R-R-L-C-R-C-H-P-F-S-A-G-G-V-D-L-V-P-P-P-N-S-D-A-R-N-A-P-H-E-A-E-A-S-S-H-R-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-V-M-L-R-R-L-V-V-L-P-V-R-F-Y-Q-Y-C-I-S-P-L-F-P-P-A-C-R-Y-V-P-T-C-S-A-Y-T-A-E-A-V-M-R-H-G-V-M-R-G-L-W-L-A-A-R-R-I-L-R-C-H-P-W-C-A-G-G-H-D-P-V-P-P-V-P-P-Q-R-Y-P-S-A-Q-E-H"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-L-V-N-C-I-K-L-G-R-E-A-E-G-L-D-F-P-P-Y-P-G-A-L-G-K-R-I-W-E-E-V-S-K-Q-A-W-A-D-W-M-K-Q-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-Q-Y-L-A-R-Q-M-E-K-H-F-F-G-D-G-A-D-A-V-Q-G-Y-V-P-P-T-P-P-G-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-C-L-K-I-L-R-F-Y-Q-K-F-L-S-P-L-K-P-A-A-C-R-Y-Y-P-S-C-S-E-Y-A-L-W-Q-F-Q-K-K-N-F-F-L-A-F-F-S-T-F-F-R-I-L-R-C-N-P-F-F-K-G-G-F-D-Y-P-R-V-S-K-N-F-Y-P-I-N-L-C-F-K-P-I-F-L-A-K-K-Q-L-C-F-L-Y-I-P-Y-K-N-K-S-F-Y-L-I-K-I-I-F-K-R-T-N-Q"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-H-C-I-K-L-G-K-E-A-E-G-L-D-F-A-P-Y-P-G-D-L-G-K-R-I-Y-D-N-V-S-K-Q-A-W-A-D-W-I-K-H-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-Q-Y-L-A-R-Q-M-E-N-H-F-F-G-S-G-A-D-A-A-A-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-Q-C-I-K-L-G-K-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-Q-R-I-W-A-N-V-S-K-Q-A-W-A-G-W-L-K-H-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-Q-Y-L-A-R-Q-M-E-N-H-F-F-G-S-G-A-D-A-A-A-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-A-T-A-D-H-E-A-T-G-L-D-C-D-H-A-I-R-R-L-L-R-R-I-D-A-H-I-A-D-E-P-R-D-S-P-V-R-R-Y-L-E-R-E-L-G-G-R-E-G-T-E-A-D-T-R-L-V-V-H-A-Q-I-N-V-V-R-E-L-F-E-R-R-S-D-A-D-G-L-R-L-L-S-N-I-E-R-E-C-C"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-K-V-H-C-V-K-L-Q-Q-E-A-D-G-L-D-R-P-P-Y-P-G-E-L-G-Q-R-I-Y-D-N-V-S-K-Q-A-W-S-M-W-V-Q-Q-Q-T-M-L-I-N-E-Y-R-L-T-P-A-D-P-K-A-R-S-F-L-E-R-E-M-E-N-F-F-F-G-Q-G-S-A-P-P-P-D-F-S-P-D-H-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-T-K-I-N-K-A-I-A-L-V-F-V-S-L-I-S-F-Y-Q-K-W-I-S-P-L-F-G-P-S-C-R-F-I-P-S-C-S-A-Y-G-I-E-A-V-N-K-H-G-P-W-R-G-G-W-L-T-L-K-R-L-S-K-C-H-P-F-T-P-C-G-C-D-P-V-P-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-E-S-N-T-L-S-G-G-I-F-A-L-L-N-R-A-I-G-S-V-L-L-A-L-I-G-F-Y-R-T-W-L-S-P-L-L-G-P-H-C-R-F-I-P-S-C-S-A-Y-G-L-E-A-I-Q-R-H-G-P-W-R-G-G-W-L-T-L-R-R-L-S-R-C-H-P-F-T-P-C-G-C-D-P-V-P-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-N-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-P-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-Q-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-K-Q-T-N-N-L-I-T-E-R-T-H-P-C-H-K-P-M-R-H-T-S-H"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-S-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-H-L-E-H-E-T-V-A-K-N-P-S-K-Q-R-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-D-S-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-A-E-K-A"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-A-D-K-Y-D-V-F-D-Q-L-G-E-L-E-N-T-L-N-T-T-L-T-Q-I-S-G-I-R-Q-V-L-E-A-S-M-T-E-N-A-T-L-R-M-E-L-E-K-L-R-D-R-L-A-E-F-E-K-K-E-V-K-K-E-T-P-K-D-Q-P-N-P-N-L-I-Q-I-F-N-E-G-F-H-I-C-H-L-H-Y-A-E-R-L-A-E-G-E-S-C-L-D-C-L-E-L-L-Y-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-V-L-V-K-A-V-H-C-Y-Q-R-W-I-S-P-A-L-P-P-A-C-R-Y-Y-P-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-P-D-K-G-L-A-M-G-T-A-R-I-L-R-C-H-P-F-C-Q-P-G-Y-D-L-V-P-E-H-F-S-L-R-R-N-W-A-E-P-E-K-K-E-E-E-D-S-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-T-L-F-E-F-Y-A-T-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-N-I-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-V-L-E-S-Y-E-E-K-L-H-L-F-S-N-Y-V-V-R-N-Q-L-L-E-E-L-M-K-K-Y-P-S-D-Q-Y-L-I-S-K-L-Q-E-I-Q-Q-I-D-E-E-E-F"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-V-L-I-A-L-L-R-F-Y-K-L-A-V-S-P-L-L-G-S-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-A-R-R-L-C-R-C-H-P-F-S-A-G-G-V-D-L-V-P-P-P-N-S-D-A-R-N-A-P-H-E-A-E-A-S-S-H-R-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-H-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-L-Y-E-S-V-S-K-Q-A-W-Q-D-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-A-Q-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-H-C-A-L-L-K-K-D-A-D-G-L-D-F-A-P-Y-P-G-E-L-G-Q-R-I-F-D-N-V-S-K-E-A-W-A-Q-W-L-K-H-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-Q-Y-L-A-R-Q-M-E-N-Y-F-F-G-A-G-A-E-Q-P-A-G-Y-V-P-P-T-P-T"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-D-L-F-D-A-L-D-D-F-S-Q-T-L-L-V-T-L-A-E-V-E-A-V-K-K-N-L-K-S-V-V-E-E-N-I-A-L-H-L-E-N-D-K-L-R-E-R-L-G-E-V-E-K-E-T-P-T-K-T-K-K-N-R-D-N-L-R-K-L-Y-Y-D-G-F-H-V-C-T-D-F-Y-G-Q-R-R-E-N-D-A-E-C-M-F-C-D-E-L-L-F-R-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-T-S-F-L-F-E-G-K-E-V-E-I-E-G-F-V-P-E-K-D-Q-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-L-Q-W-L-A-T-T-L-I-R-G-Y-Q-V-F-I-S-P-I-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-K-V-H-G-T-A-K-G-C-W-F-A-L-K-R-I-L-K-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-D-K-V-Y-E-A-A-L-L-L-D-F-Y-G-Q-L-L-T-K-R-Q-F-E-I-L-D-L-Y-L-N-N-D-Y-S-L-G-E-I-A-E-H-L-N-I-S-R-Q-G-V-Y-D-N-I-K-R-G-R-A-M-L-D-R-M-E-E-K-L-G-L-V-H-K-F-L-Q-Q-K-N-R-A-L-E-I-L-K-D-I-K-S-I-D-I-S-S-M-S-V-E-D-A-K-I-L-K-R-V-E-E-R-I-E-E-I-V-E-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-F-R-R-W-V-I-Y-I-I-R-L-Y-Q-R-W-I-S-P-L-K-T-M-P-S-C-R-F-Y-P-T-C-S-Q-Y-A-I-D-A-V-G-R-Y-G-V-I-K-G-G-F-M-A-L-K-R-I-L-K-C-H-P-F-H-P-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-I-T-D-V-R-I-R-K-I-D-S-E-G-K-M-K-A-V-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-S-Q-N-G-L-F-I-A-M-P-S-R-K-A-P-D-G-E-F-R-D-I-A-H-P-I-N-A-E-T-R-S-K-I-Q-T-A-I-L-D-K-Y-E-S-I-C-A-G-S-T-E-T-E-G-N-N"} +{"text": "### FUNCTION Involved in ribosome biogenesis, probably through modulation of rDNA transcription ### SEQUENCE -M-S-F-K-S-T-A-S-K-H-Q-A-Q-T-T-V-S-K-L-F-A-N-I-L-P-N-H-T-I-G-N-D-E-D-K-Q-E-K-L-S-S-T-Q-L-L-S-N-Q-L-K-Q-S-S-V-P-L-K-K-V-K-K-K-T-N-A-K-I-K-K-I-N-D-S-N-T-K-F-K-K-F-V-K-Y-N-I-I-K-S-R-E-E-H-T-V-E-E-Q-K-Y-L-K-K-L-V-K-R-N-A-S-Q-I-K-N-L-S-H-I-D-N-M-Q-I-E-E-E-L-S-D-V-R-A-S-L-I-D-K-I-G-K-K-E-N-K-R-L-R-K-R-K-L-T-S-A-K-N-S-K-F-D-D-F-D-N-K-V-K-R-G-F-I-S-V-P-G-L-T-P-G-L-A-P-I-D-Y-N-E-S-D-S-E"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-I-R-V-I-S-L-F-L-V-F-V-S-L-A-S-A-N-I-F-D-F-L-N-N-N-F-A-G-R-G-Q-Q-Q-G-G-Q-V-Q-T-P-E-Q-Y-E-N-A-I-L-N-T-N-C-G-K-Y-V-C-P-D-T-G-M-C-V-E-A-P-K-F-C-P-C-P-Y-P-S-S-Q-L-R-C-F-L-P-D-G-R-Y-L-C-I-S-K-P-A-G-D-I-S-A-K-Y-D-D-P-K-S-N-W-K-V-D-A-K-D-D-N-I-R-D-C-G-W-V-S-R-A-W-R-G-L-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-Q-V-F-C-R-K-Y-Q-K-E-M-E-G-L-D-F-A-P-F-P-G-A-K-G-Q-E-F-F-E-N-V-S-K-Q-A-W-Q-E-W-L-Q-H-Q-T-T-L-I-N-E-K-R-L-N-V-F-E-P-E-A-K-K-F-L-E-E-Q-R-E-K-F-F-N-N-D-E-S-V-E-K-A-E-G-W-K-P-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-R-I-L-R-W-F-I-R-L-Y-Q-I-A-I-S-P-L-L-G-P-R-C-R-Y-I-P-T-C-S-Q-Y-A-L-E-A-L-Q-T-H-G-A-I-K-G-V-W-L-S-S-K-R-I-C-R-C-H-P-W-G-G-S-G-Y-D-P-V-P-P-K-A-I-R-F-I-S-F-H-Q-I-D-S-Q-T-H-H-V-A-V-P-F-R-D-R-L-M-K-Q-N-L-S-N-H-L-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-H-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-L-Y-E-S-V-S-K-Q-A-W-Q-D-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-A-Q-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-V-L-I-A-L-L-R-F-Y-K-L-A-V-S-P-L-L-G-S-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-A-R-R-L-C-R-C-H-P-F-S-A-G-G-V-D-L-V-P-P-P-N-S-D-A-R-N-A-P-H-E-A-E-A-S-S-H-R-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-E-Y-L-K-Q-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-S-I-S-K-Q-A-W-S-E-W-I-K-K-Q-T-M-L-V-N-E-K-K-L-S-M-M-N-A-E-H-R-K-L-L-E-T-E-M-V-N-F-L-F-E-G-K-E-V-Q-I-E-G-Y-V-P-V-E-Q-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-V-L-I-A-L-L-R-F-Y-K-L-A-V-S-P-L-L-G-S-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-A-R-R-L-C-R-C-H-P-F-S-A-G-G-V-D-L-V-P-P-P-N-S-D-A-R-N-A-P-H-E-A-E-A-S-S-H-R-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-H-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-L-Y-E-S-V-S-K-Q-A-W-Q-D-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-A-Q-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-V-L-I-A-L-L-R-F-Y-K-L-A-V-S-P-L-L-G-S-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-A-R-R-L-C-R-C-H-P-F-S-A-G-G-V-D-L-V-P-P-P-N-S-D-A-R-N-A-P-H-E-A-E-A-S-S-H-R-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-H-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-L-Y-E-S-V-S-K-Q-A-W-Q-D-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-A-Q-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-F-K-T-I-N-K-S-I-T-S-I-L-L-L-L-I-S-F-Y-Q-K-W-F-S-P-F-F-G-P-R-C-R-F-I-P-S-C-S-S-Y-G-Y-E-A-I-T-R-H-G-P-W-K-G-G-W-L-T-L-K-R-L-S-R-C-H-P-L-T-P-C-G-C-D-P-V-P-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-P-L-A-Q-V-L-A-L-P-V-R-A-Y-R-L-L-L-S-P-W-V-G-H-G-C-R-Y-Q-P-T-C-S-V-Y-A-L-D-A-L-E-R-H-G-A-L-K-G-G-W-L-A-A-R-R-I-L-S-C-H-P-W-G-G-S-G-Y-D-P-V-P-G-A-D-P-E-H-D-R-R-P-R-G"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-G-N-I-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-E-K-L-E-L-P-A-T-R-I-P-I-L-G-R-I-Q-D-P-D-F-V-R-E-P-Y-V-L-V-L-P-T-Y-G-G-G-H-A-N-G-P-D-P-D-A-G-G-Y-V-P-K-Q-V-I-A-F-L-N-N-E-H-N-R-S-L-I-R-G-V-I-A-A-G-N-T-N-F-G-A-E-F-G-Y-A-G-D-V-V-S-R-K-C-G-V-P-Y-L-Y-R-F-E-L-M-G-T-T-D-D-V-L-A-V-R-A-G-L-E-N-F-W-K-E-Q-T-C-H-P-P-S-Q-L-Q-S-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-Q-Y-L-K-K-E-A-D-G-L-A-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-Q-E-A-W-S-L-W-Q-A-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-V-N-F-L-F-E-G-K-E-V-E-I-E-G-Y-V-P-Q-K-D-D-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-A-Q-S-P-L-Q-W-L-A-T-K-L-I-R-G-Y-Q-I-F-I-S-P-I-L-G-P-K-C-R-F-H-P-T-C-S-N-Y-A-L-E-A-I-R-L-H-G-F-V-K-G-S-W-F-A-G-K-R-V-L-K-C-H-P-L-H-P-G-G-E-D-P-V-P-P-K-N-N-R-C-N-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-M-V-H-C-I-K-L-D-K-E-A-E-A-L-D-F-P-P-Y-P-G-E-L-G-K-R-I-Y-E-S-V-S-K-E-A-W-A-A-W-L-K-H-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-V-R-A-R-K-Y-L-A-T-Q-M-E-K-H-F-F-G-E-G-A-D-A-A-Q-G-Y-V-P-P-T-E"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-V-T-D-V-R-L-R-R-V-N-T-E-G-R-M-K-A-I-A-S-I-T-L-D-N-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-A-T-R-G-K-I-Q-E-A-I-L-A-E-Y-H-R-L-G-K-L-E-E-E-L-E-E-A-G-A-S"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-K-E-F-H-K-I-N-L-L-N-D-Y-Y-G-S-L-L-T-E-R-Q-Q-N-F-I-E-L-Y-Y-G-E-D-L-S-L-G-E-I-A-E-Q-Y-N-V-T-R-Q-A-V-H-D-T-L-K-R-A-E-Q-T-L-T-N-Y-E-E-K-L-G-L-V-S-K-F-S-Q-E-S-K-S-L-V-E-V-I-N-L-L-D-G-Y-E-S-G-E-A-P-E-G-L-E-K-S-K-G-I-L-K-K-I-L-E-K-R-Q-D-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-Q-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-S-V-S-K-E-A-W-Q-G-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-D-G-A-D-Q-A-S-G-Y-V-P-P-T-E-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-V-L-I-A-L-L-R-F-Y-K-V-A-V-S-P-M-L-G-D-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-V-R-R-V-C-R-C-H-P-F-S-A-G-G-I-D-L-V-P-P-P-N-S-D-I-R-A-R-G-E-A-D-A-R-S-H-R-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-L-I-V-Y-F-S-S-A-T-D-N-T-H-R-F-V-Q-K-L-D-L-P-N-V-R-I-P-L-T-R-V-E-E-P-L-K-I-N-E-P-Y-V-L-I-T-P-T-Y-G-G-G-V-S-M-T-G-E-N-S-R-P-V-P-P-Q-V-I-R-F-L-N-D-E-H-N-R-S-F-I-R-A-V-V-A-G-G-N-S-N-F-G-S-D-F-G-L-A-G-E-I-I-S-K-K-C-K-V-P-Y-V-Y-R-F-E-L-M-G-N-E-E-D-V-S-I-L-R-G-G-L-T-Q-N-A-Q-A-L-G-L-E-P-Q-E-P-V-T-S-R"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-Q-S-P-V-L-L-Q-L-L-L-L-A-L-M-G-T-V-S-A-Q-F-G-G-F-F-D-Q-M-F-G-G-G-G-G-G-G-G-G-Q-Q-Q-R-Q-E-Q-N-V-P-S-D-S-A-W-Y-R-S-N-V-D-A-A-V-C-S-N-Y-L-C-P-D-T-L-A-C-V-H-F-P-H-H-C-P-C-P-F-P-D-H-E-D-K-F-E-L-A-E-G-Q-R-I-C-V-S-R-G-G-F-K-A-G-E-A-A-R-K-V-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-Q-R-L-K-K-E-G-P-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-E-A-W-T-E-W-Q-K-K-Q-V-M-L-I-N-E-K-K-L-N-M-M-N-L-E-H-R-Q-L-L-E-K-E-M-V-S-Y-L-F-E-A-G-E-V-A-I-D-G-Y-T-P-P-S-Q"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-S-D-Q-V-L-S-A-L-E-H-F-F-L-R-W-Q-R-D-G-E-A-R-R-G-L-P-L-C-E-W-E-A-D-W-R-S-P-C-E-L-D-E-P-R-E-G-R-V-A-W-R-P-H-Q-R-Q-Q-A-A-D-F-A-A-M-A-N-A-L-E-L-V-L-H-P-A-A-Q-A-L-F-G-H-W-F-S-R-P-I-P-C-S-Y-K-G-L-R-L-E-I-I-L-P-W-N-E-A-D-L-N-L-L-R-E-N-L-I-G-H-L-L-M-L-R-K-L-K-R-T-P-S-L-F-I-A-T-T-R-N-E-M-T-L-V-S-L-D-N-E-S-G-Q-V-W-L-E-W-L-D-S-G-R-R-L-T-L-A-P-S-L-P-A-F-L-E-R-L-E-T-L-P-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-H-S-V-T-P-L-Q-W-V-A-V-K-L-I-R-L-Y-Q-L-I-I-S-P-L-L-G-Q-R-C-R-F-T-P-T-C-S-Q-F-A-I-E-A-I-R-L-H-G-F-I-K-G-V-W-L-A-S-K-R-L-L-K-C-H-P-L-S-E-G-G-Y-D-P-V-P-Q-P-K-R-R-N"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-Q-C-I-K-L-N-K-E-A-E-G-M-D-F-A-P-L-P-G-E-L-G-K-K-I-W-N-Q-V-S-K-E-A-W-A-A-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-L-K-Q-V-E-K-Y-F-F-E-G-G-A-D-M-A-Q-G-Y-V-P-E-A-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-N-I-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-Q-K-L-E-L-P-A-I-R-I-P-L-K-D-R-I-R-V-E-E-P-Y-V-L-I-L-P-T-Y-G-G-G-H-A-N-G-P-D-P-D-R-G-G-Y-V-P-K-Q-V-I-A-F-L-N-D-E-H-N-R-S-L-I-R-G-V-I-A-A-G-N-T-N-F-G-A-E-F-G-Y-A-G-V-V-V-S-R-K-C-D-V-P-F-L-Y-R-F-E-L-M-G-T-T-D-D-V-F-A-V-R-A-G-L-Q-D-F-W-K-D-Q-S-C-P-Q-P-S-Q-L-Q-N-R"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-K-K-D-A-E-G-Q-D-F-Q-L-Y-P-G-E-I-G-K-R-I-Y-N-E-I-S-K-E-A-W-S-Q-W-I-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-I-E-D-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-Q-D-V-H-I-A-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-L-N-I-S-T-A-L-R-S-F-T-Q-R-Y-I-D-L-W-Q-Q-Q-T-G-H-L-P-A-S-K-E-L-Y-G-V-P-S-P-C-I-V-E-T-G-E-D-Q-V-F-W-Q-P-Q-A-F-L-P-E-A-T-L-T-N-I-E-R-A-L-E-I-Q-L-H-P-D-I-H-D-F-Y-T-Q-Q-Y-A-G-D-M-M-A-D-L-G-N-H-R-F-T-L-L-Q-V-W-S-E-D-D-F-I-R-L-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-L-F-L-A-T-T-S-S-E-M-T-M-A-S-L-C-N-V-S-G-N-V-V-L-E-Q-F-G-S-D-K-R-T-L-L-A-S-T-L-S-H-F-L-D-A-L-R-P-V-L-P-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-P-L-S-P-G-S-R-I-L-I-G-L-I-R-G-Y-Q-L-V-I-S-P-L-L-G-P-R-C-R-F-H-P-T-C-S-H-Y-G-I-E-A-L-R-R-F-G-M-I-K-G-S-W-L-T-L-K-R-V-L-K-C-H-P-L-N-S-G-G-D-D-P-V-P-P-K-L-D-D-N-R-E-H"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-N-C-R-K-Y-N-Q-E-L-P-G-L-E-R-P-P-F-P-G-Q-K-G-E-D-I-Y-N-N-I-S-R-Q-A-W-D-D-W-Q-K-H-Q-T-M-L-I-N-E-R-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-G-E-M-D-K-F-F-S-G-E-D-Y-A-K-A-E-G-Y-V-P-P-S-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-I-F-D-A-L-D-D-F-S-Q-N-L-L-T-T-L-A-E-V-D-A-I-K-K-H-L-Q-G-V-I-D-E-N-T-T-L-R-L-E-N-S-K-L-R-E-R-L-E-K-E-D-K-T-G-H-K-S-S-N-F-G-K-E-N-L-E-N-I-Y-E-D-G-F-H-I-C-T-F-S-Y-G-Q-R-R-D-N-D-E-P-C-M-F-C-V-E-L-L-N-R-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-K-F-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-Q-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-L-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-Q-I-F-D-E-I-L-N-K-Y-P-E-D-A-Y-L-K-E-K-I-A-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-I-F-D-A-L-D-D-F-S-Q-N-L-L-T-T-L-A-E-V-D-A-I-K-K-H-L-Q-G-V-I-D-E-N-T-T-L-R-L-E-N-S-K-L-R-E-R-L-E-K-E-D-K-T-G-H-K-S-S-N-F-G-K-E-N-L-E-N-I-Y-E-D-G-F-H-I-C-T-F-S-Y-G-Q-R-R-D-N-D-E-P-C-M-F-C-V-E-L-L-N-R-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-K-F-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-Q-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-L-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-Q-I-F-D-E-I-L-N-K-Y-P-E-D-A-Y-L-K-E-K-I-A-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-V-L-V-Y-F-S-S-S-S-E-N-T-L-R-F-I-E-R-V-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-P-H-N-R-A-L-I-R-G-V-I-A-A-G-N-R-N-F-G-D-A-F-C-R-A-G-D-L-I-S-Q-K-C-G-V-P-Y-L-Y-R-F-E-L-M-G-T-Q-Q-D-V-E-N-V-R-K-G-V-N-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-I-E-T-A-N-A-L-T-A-F-T-A-R-Y-C-D-A-W-H-E-M-N-G-T-W-P-Q-S-E-E-L-Y-G-V-P-S-P-C-I-I-T-T-M-D-D-K-I-L-W-Q-P-Q-P-F-S-L-E-Q-T-V-N-A-V-E-R-A-M-D-I-V-V-Q-P-A-V-H-A-F-Y-T-T-Q-F-A-G-D-M-Q-A-R-F-A-N-E-T-M-T-L-L-Q-T-W-S-E-N-D-F-Q-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-A-P-T-L-F-I-A-T-L-D-S-E-L-D-V-I-A-V-C-N-L-N-G-E-V-I-K-E-T-L-G-T-R-K-R-D-V-L-A-P-S-L-A-D-F-L-N-Q-L-E-P-V-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-I-F-C-T-Y-L-Q-R-D-A-E-G-Q-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-N-E-I-S-K-E-A-W-A-Q-W-Q-Q-K-Q-T-M-L-I-N-E-K-K-L-T-M-M-N-P-D-H-R-K-L-L-E-A-E-M-V-N-F-L-F-E-G-K-E-V-H-I-E-G-Y-T-P-P-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-G-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-P-L-A-Q-I-F-A-L-P-V-R-A-Y-R-L-L-L-S-P-W-V-G-H-G-C-R-Y-Q-P-T-C-S-V-Y-A-L-E-A-L-E-R-H-G-A-L-K-G-G-W-L-A-A-R-R-I-L-R-C-H-P-W-G-G-S-G-Y-D-P-V-P-G-A-D-P-E-H-D-R-R-P-R-G"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-N-D-H-T-P-D-R-Y-V-T-F-L-G-I-D-C-D-A-K-A-D-R-M-M-E-M-L-S-A-R-L-A-S-T-D-S-P-W-V-R-Y-F-E-Q-K-L-A-E-K-A-R-M-A-T-D-N-L-H-F-V-G-S-Q-I-N-S-L-Y-S-F-F-E-E-A-E-D-E-E-G-L-D-L-L-W-H-L-E-H-N-C-C"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-V-T-D-V-R-I-R-K-I-T-N-E-G-R-M-K-A-I-V-S-V-T-F-D-N-C-F-V-V-H-D-I-K-I-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-E-G-E-F-K-D-I-A-H-P-I-N-Q-E-M-R-D-M-V-Q-K-A-V-I-E-K-Y-E-A-V-I-S-A-G-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-L-C-R-K-Y-K-Q-E-L-P-G-L-D-R-A-P-Y-P-G-P-K-G-E-D-I-F-A-N-V-S-K-Q-A-W-D-E-W-Q-K-H-Q-T-M-L-I-N-E-R-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-T-E-M-D-K-F-L-S-G-E-E-Y-A-Q-A-E-G-Y-V-P-P-S-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-T-S-F-L-F-E-G-K-E-V-E-I-E-G-F-V-P-E-K-D-Q-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-L-Q-W-L-A-T-T-L-I-R-G-Y-Q-I-F-I-S-P-I-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-K-V-H-G-T-A-K-G-C-W-F-A-L-K-R-I-L-K-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-A-L-T-S-V-V-L-A-P-R-N-A-A-I-A-V-I-S-L-Y-R-R-V-V-S-P-I-Y-G-D-V-C-R-Y-Y-P-S-C-S-A-Y-G-L-E-A-V-Q-E-H-G-L-V-H-G-G-V-L-A-A-W-R-V-C-R-C-H-P-W-A-E-G-G-I-D-D-V-P-A-R-R-V-Q-Q-Y-R-R-T-R-L-G-F-V-V-A-P-S-H-G-K-G"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-H-L-I-Y-F-L-F-L-V-V-G-C-S-A-S-L-F-D-F-I-Q-N-Q-F-G-G-G-G-Q-A-Q-K-S-P-E-H-Y-E-A-Q-V-L-N-S-N-C-D-K-Y-L-C-P-G-T-S-L-C-V-D-A-P-K-F-C-P-C-P-Y-P-S-S-Q-L-R-C-F-L-P-D-G-R-Y-L-C-I-S-K-P-A-G-D-V-A-A-N-Y-D-D-P-R-T-N-W-K-V-D-A-K-D-D-N-I-R-D-C-G-W-V-S-R-A-W-K-G-V-V"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-L-Q-K-F-L-I-C-L-S-L-I-F-T-L-A-S-A-N-L-F-D-F-L-N-N-Q-F-Q-G-G-N-G-G-G-G-G-G-R-H-Q-N-G-G-S-K-S-P-Q-Q-H-E-E-A-M-L-N-A-N-C-N-T-Y-L-C-P-D-T-G-I-C-V-D-A-P-K-F-C-P-C-P-Y-P-S-S-Q-L-R-C-F-L-P-D-G-R-Y-V-C-I-S-K-P-A-G-Y-G-I-A-D-K-Y-N-D-P-Q-T-N-F-K-I-D-A-K-D-D-N-I-R-D-C-G-W-V-N-R-A-W-R-N-E-K-L-K-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-T-R-L-Q-K-E-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-C-K-E-A-W-A-Q-W-Q-T-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-D-P-E-H-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-K-E-V-H-I-E-G-Y-T-P-P-A-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-T-A-T-K-L-L-R-G-G-V-R-A-Y-Q-L-T-L-S-S-V-L-G-G-Q-C-R-F-Y-P-S-C-S-A-Y-A-M-E-A-L-A-V-H-G-A-L-H-G-S-A-L-A-A-R-R-I-L-R-C-H-P-W-N-P-G-G-V-D-P-V-P-P-A-H-H-H-D-E-M-K-Q-N-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-N-I-I-A-T-R-S-I-L-F-Y-Q-R-Y-I-S-P-F-K-G-S-S-C-R-F-Y-P-S-C-S-H-Y-S-L-Q-S-L-E-K-Y-G-F-L-K-G-L-L-Y-S-V-R-R-I-M-K-C-H-P-F-H-P-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-E-I-V-E-M-S-L-L-L-D-F-Y-G-S-L-L-T-E-K-Q-N-K-I-M-D-L-Y-Y-N-N-D-Y-S-L-K-E-I-S-E-L-T-N-T-S-R-Q-A-V-H-D-I-V-K-R-C-H-K-A-L-L-Q-Y-E-E-K-L-H-M-M-E-R-F-I-N-L-E-N-S-K-E-K-L-L-N-M-L-N-K-V-T-K-E-N-I-K-E-I-D-H-I-K-K-Y-I-I-D-N-I"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-V-R-K-I-A-A-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-Y-K-D-I-A-H-P-I-N-T-E-T-R-E-K-I-Q-K-S-I-I-E-E-Y-E-R-A-K-M-E-E-E-S-S-E-K-V-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-L-L-I-C-I-I-K-M-Y-R-K-Y-I-S-P-L-K-R-P-S-C-R-F-Y-P-T-C-S-Q-Y-S-I-E-A-I-E-K-Y-G-A-L-K-G-T-L-I-S-I-K-R-I-L-K-C-H-P-F-N-E-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-C-K-L-K-Q-E-A-E-G-L-E-K-Q-P-F-P-G-E-L-G-K-K-V-F-N-E-V-S-K-Q-A-W-N-M-W-L-S-H-Q-T-M-L-I-N-E-Y-R-L-N-L-I-E-A-R-A-R-E-F-L-K-E-E-M-Q-K-Y-F-F-G-E-G-S-E-K-P-S-G-Y-K-E-I-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-L-I-M-L-I-R-F-Y-Q-R-Y-I-S-P-L-K-P-P-T-C-R-F-T-P-T-C-S-N-Y-F-I-Q-A-L-E-K-H-G-L-L-K-G-T-F-L-G-L-R-R-I-L-R-C-N-P-L-S-K-G-G-Y-D-P-V-P-E-E-F-S-F-K-P-R-R-R-W-S"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-R-N-E-I-F-E-K-I-M-R-L-E-M-N-V-N-Q-L-S-K-E-T-S-E-L-K-A-H-A-V-E-L-V-E-E-N-V-A-L-Q-L-E-N-D-N-L-K-K-V-L-G-N-D-E-P-T-T-I-D-T-A-N-S-K-P-A-K-A-V-K-K-P-L-P-S-K-D-N-L-A-I-L-Y-G-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-F-C-L-E-V-L-S-D"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-V-P-D-K-N-A-T-S-E-D-S-E-E-A"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-F-L-I-F-L-I-K-V-Y-R-K-Y-I-S-P-L-K-V-P-C-C-R-F-Y-P-T-C-S-Q-Y-V-L-E-A-L-Q-K-H-G-I-I-K-G-G-F-M-S-I-K-R-I-L-R-C-N-P-F-C-K-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-V-R-K-I-A-A-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-F-K-D-I-A-H-P-I-N-T-Q-T-R-E-K-I-Q-K-A-I-L-G-E-Y-E-K-V-K-N-E-E-T-V-T-E-E-K-V-E-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-E-R-I-R-L-S-I-L-L-D-I-Y-G-E-L-L-T-E-K-Q-R-N-V-L-D-L-Y-Y-N-Q-D-L-S-L-A-E-I-A-E-H-T-S-T-S-R-Q-A-V-Y-D-I-I-K-R-C-H-M-L-L-V-H-Y-E-D-K-L-N-L-M-E-E-K-K-N-I-E-E-N-K-K-G-I-I-D-F-I-D-S-L-Y-S-D-K-N-A-E-V-L-D-K-I-K-N-Y-I-M-N-N-I"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-E-Y-L-K-K-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-S-V-S-K-Q-A-W-S-E-W-I-K-K-Q-T-M-L-V-N-E-K-K-L-N-M-M-N-A-E-H-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-K-D-V-H-I-E-G-Y-V-P-P-S-N"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-E-Y-L-K-K-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-S-V-S-K-Q-A-W-G-E-W-I-K-K-Q-T-M-L-V-N-E-K-K-L-N-M-M-N-A-E-H-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-K-D-V-H-I-E-G-Y-V-P-P-S-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-E-T-H-S-L-G-T-K-I-L-I-K-I-I-R-L-Y-Q-I-M-I-S-P-F-I-G-A-R-C-R-F-V-P-T-C-S-C-Y-G-I-E-A-L-K-T-H-G-L-L-K-G-G-W-L-T-L-K-R-V-L-K-C-H-P-L-N-A-G-G-F-D-P-V-P-P-K-T-N-N-N-D-E-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-G-R-L-I-I-L-L-A-R-A-W-Q-M-G-P-S-L-V-L-P-P-T-C-R-Y-V-P-S-C-S-A-Y-T-I-E-A-V-S-R-Y-G-A-L-K-G-G-W-L-G-F-R-R-I-C-R-C-H-P-W-G-G-S-G-F-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-R-I-L-C-D-L-I-R-W-Y-Q-Q-G-I-S-A-Q-R-P-F-R-V-C-R-F-T-P-S-C-S-Q-Y-M-L-E-A-L-Q-R-F-G-L-K-G-I-L-L-G-S-W-R-L-L-R-C-Q-P-F-S-R-G-G-Y-D-P-V-P-N-H-F-T-F-R-R-Q-G"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-N-Y-R-I-N-S-L-F-E-F-Y-Q-P-L-L-T-K-K-Q-N-D-Y-L-E-L-Y-Y-G-D-D-Y-S-L-G-E-I-A-E-N-F-H-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-S-I-L-E-D-Y-E-A-K-L-H-L-Y-A-E-F-Q-V-R-N-Q-Q-A-D-R-I-Q-R-Y-V-R-E-N-Y-P-D-D-A-T-L-N-H-L-V-N-H-L-E-S-L-E-E-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-S-C-G-G-K-H-T-G-K-G-A-P-K-P-Y-S-R-N-F-T-D-P-W-R-K-T-P-G-R-L-F-G-T-A-L-I-R-F-Y-Q-I-T-L-S-S-L-I-G-N-S-C-R-H-L-P-T-C-S-E-Y-A-Y-E-A-I-A-R-H-G-L-W-R-G-G-W-M-G-F-F-R-V-V-R-C-G-P-F-G-T-H-G-F-D-P-V-P-R-E-L-S-P-D-L-K-W-Y-M-P-W-R-Y-W-R-C-S-A-S-R-T-G-K"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-L-I-V-Y-F-S-S-R-S-G-N-T-H-R-F-V-E-R-L-G-V-R-S-S-R-I-P-L-E-A-S-G-A-L-Q-V-R-E-P-F-V-L-V-T-P-T-Y-G-G-G-S-T-K-G-A-V-P-N-P-V-I-R-F-L-N-D-A-D-N-R-A-L-I-R-G-V-I-A-A-G-N-S-N-F-G-E-A-F-C-I-A-G-N-I-I-S-A-K-C-G-V-P-Y-L-Y-R-F-E-L-L-G-T-A-E-D-V-G-N-V-R-N-G-M-E-Q-F-W-T-R-Q-T-Q-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-M-C-R-K-Y-Q-E-E-L-P-G-L-E-R-P-P-Y-P-G-A-K-G-Q-D-I-F-E-H-I-S-Q-K-A-W-A-D-W-Q-K-H-Q-T-M-L-I-N-E-K-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-A-E-M-D-K-F-F-A-G-E-E-Y-A-Q-A-E-G-Y-V-P-P-A-E"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-S-S-T-L-I-V-Q-L-D-M-R-T-L-C-Q-E-A-D-V-T-A-E-C-V-I-E-I-V-E-H-G-I-V-E-P-S-G-R-T-P-E-D-W-L-F-D-D-Q-A-P-L-V-T-K-R-A-V-K-L-H-Q-E-L-E-L-E-W-E-G-V-A-L-A-L-E-L-L-Q-E-V-Q-Q-L-R-S-E-N-N-M-L-K-Q-R-L-G-R-F-I-Q-M"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-L-A-L-V-P-I-Q-F-Y-R-Y-A-I-S-P-L-M-A-N-H-C-R-F-F-P-S-C-S-C-Y-A-Y-E-A-I-E-N-H-G-I-W-R-G-G-W-L-A-V-R-R-L-G-R-C-H-P-W-N-D-G-G-F-D-P-V-P-P-A-P-S-S-R-T-S-S-I-A-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-L-S-Y-L-L-L-L-P-V-Y-F-Y-R-G-Y-I-S-P-M-T-P-P-S-C-R-F-V-P-T-C-S-E-Y-A-I-E-A-I-K-K-H-G-P-F-K-G-L-Y-L-A-V-R-R-I-L-R-C-H-P-W-G-G-S-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-R-F-F-T-T-L-L-L-L-P-V-Y-F-Y-K-Y-C-I-S-L-M-T-P-A-S-C-R-Y-T-P-T-C-S-E-Y-A-V-Q-A-L-K-K-Y-G-P-V-K-G-L-Y-L-A-V-K-R-I-L-R-C-H-P-W-G-G-S-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-I-L-A-L-I-R-F-Y-Q-K-F-I-S-P-L-K-P-P-T-C-I-Y-T-P-T-C-S-E-Y-T-Y-Q-A-V-K-K-F-G-V-F-K-G-L-F-L-G-F-K-R-I-L-R-C-N-P-L-H-E-G-G-E-D-P-V-P-D-K-F-Y-I-I-K-G-R-R-L-D"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-I-R-K-I-A-S-E-G-K-M-K-G-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-M-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-F-K-D-I-A-H-P-I-N-T-E-A-R-E-K-I-Q-T-A-I-L-E-A-Y-E-K-A-V-S-E-E-V-V-E-G"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-D-R-V-E-I-S-L-L-M-D-F-Y-G-P-L-L-T-E-K-Q-S-E-I-M-Q-W-Y-Y-N-D-D-L-S-L-A-E-I-A-E-L-N-Q-T-S-R-Q-A-I-H-D-L-I-K-R-C-Y-K-Q-L-L-S-Y-E-S-K-L-N-L-L-Q-K-S-I-N-R-K-K-E-I-M-N-F-L-E-H-L-K-N-K-Y-S-I-D-D-E-D-I-I-K-Y-K-E-K-L-E-N-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-L-I-R-L-I-K-F-Y-R-K-Y-I-S-P-G-R-S-S-C-C-R-F-V-P-T-C-S-Q-Y-A-I-D-A-I-N-K-Y-G-A-F-K-G-S-A-L-A-V-Y-R-I-L-R-C-N-P-F-C-K-G-G-Y-D-P-V-R"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-R-N-E-I-F-E-K-I-M-R-L-E-M-N-V-N-Q-L-S-K-E-T-S-E-L-K-A-L-A-V-E-L-V-E-E-N-V-A-L-Q-L-E-N-D-N-L-K-K-V-L-G-N-D-E-P-T-T-I-D-T-A-N-S-K-P-A-K-A-V-K-K-P-L-P-S-K-D-N-L-A-I-L-Y-G-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-F-C-L-E-V-L-S-D"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-V-P-D-K-N-A-T-S-E-D-S-E-E-A"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-V-R-I-F-T-S-I-L-L-G-L-L-L-L-V-T-G-T-R-S-Q-F-Q-F-F-E-Q-M-F-G-G-G-Q-Q-Q-Q-H-D-S-R-E-Q-N-V-P-S-D-S-D-W-Y-Q-R-T-Y-D-N-A-R-C-S-N-Y-L-C-P-G-T-L-A-C-V-A-V-P-H-H-C-P-C-Q-H-P-A-V-E-D-K-F-E-L-G-D-G-S-A-I-C-V-S-K-G-G-F-K-F-G-E-A-A-R-K-V-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-A-K-V-L-F-S-L-F-S-F-L-F-L-I-I-G-V-S-A-Q-F-Q-F-F-E-Q-M-F-N-G-Q-Q-Q-Q-H-Q-R-Q-P-Q-D-V-P-S-D-S-Q-W-Y-Q-D-N-Y-D-R-A-H-C-T-S-Y-L-C-P-G-T-L-S-C-V-A-F-P-H-H-C-P-C-A-H-P-T-Y-E-E-K-F-E-L-A-D-G-N-A-I-C-I-S-K-G-G-F-K-A-G-E-A-A-R-K-V-E-L-A-R-K-G-L-I"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-M-I-H-C-I-K-L-D-K-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-K-R-I-Y-E-T-V-S-K-E-A-W-A-A-W-L-K-H-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-V-R-A-R-K-Y-L-A-T-Q-M-E-K-H-F-F-G-D-G-A-D-A-A-Q-G-Y-V-P-P-T-Y"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-L-I-V-Y-F-S-S-R-S-E-N-T-H-R-F-V-Q-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-H-L-R-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-A-I-R-F-L-N-D-V-H-N-R-Q-L-I-R-G-V-I-A-A-G-N-R-N-F-G-D-G-W-G-R-A-G-D-V-I-A-Q-K-C-A-V-P-Y-L-Y-R-F-E-L-M-G-T-P-D-D-I-N-T-V-R-K-G-V-S-E-F-W-Q-R-Q-P-Q-N-V"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-H-Q-T-A-E-A-L-R-A-F-T-Q-R-Y-C-A-V-W-Q-Q-Q-R-H-S-L-P-R-S-E-E-L-Y-G-V-P-S-P-C-V-V-D-T-Q-G-E-A-V-F-W-Q-P-Q-P-F-S-L-A-Q-N-I-S-A-V-E-R-A-L-D-I-V-V-Q-Q-P-L-H-S-Y-Y-T-T-Q-F-A-G-D-M-S-G-R-F-A-G-E-T-L-T-L-L-Q-T-W-S-E-E-D-F-Q-R-V-Q-E-N-L-I-G-H-L-V-V-Q-K-R-L-K-L-S-P-T-L-F-I-A-T-L-E-S-E-L-D-V-I-S-V-C-N-L-S-G-E-V-V-K-E-T-L-G-T-A-K-R-I-T-L-S-P-S-L-A-G-F-L-N-H-L-E-P-V-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-Q-R-E-A-D-G-Q-D-F-Q-L-Y-P-G-E-L-G-K-R-I-Y-N-E-I-S-K-E-A-W-A-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-P-E-H-R-K-L-L-E-Q-E-M-V-Q-F-L-F-E-G-K-D-V-H-I-E-G-Y-T-P-P-E-K-Q"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-I-R-K-V-A-A-E-G-K-M-K-A-I-V-S-V-T-F-D-E-E-F-V-V-H-D-I-K-I-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-M-G-E-G-D-F-R-D-I-A-H-P-I-N-S-D-T-R-S-K-I-Q-D-A-I-F-A-E-Y-A-I-M-N-E-E-V-Q-V-Q-V-Q-V-T-E-E-A-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-K-F-L-I-K-L-I-T-L-Y-Q-K-W-I-S-P-L-K-G-Q-T-C-R-F-Y-P-T-C-S-S-Y-S-I-S-A-Y-N-T-Y-G-F-F-R-G-T-Y-L-T-I-R-R-L-L-K-C-H-P-F-H-P-G-G-F-D-P-L-K"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-R-N-E-I-F-E-K-I-M-R-L-E-M-N-V-N-Q-L-S-K-E-T-S-E-L-K-A-H-A-V-E-L-V-E-E-N-V-A-L-Q-L-E-N-D-N-L-K-K-V-L-G-N-D-E-P-T-T-I-D-T-A-N-S-K-P-A-K-A-V-K-K-P-L-P-S-K-D-N-L-A-I-L-Y-G-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-F-C-L-E-V-L-S-D"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-V-P-D-K-N-A-T-S-E-D-S-E-E-A"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-M-C-R-K-Y-H-E-E-L-P-G-L-D-R-P-P-Y-P-G-A-K-G-E-D-I-Y-N-N-V-S-R-K-A-W-D-E-W-Q-K-H-Q-T-M-L-I-N-E-R-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-Q-E-M-D-K-F-L-S-G-E-D-Y-A-K-A-D-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-A-T-V-I-A-K-V-K-V-M-P-T-S-P-E-V-D-K-E-S-L-K-A-T-L-K-E-L-V-E-N-N-D-A-K-C-R-G-V-S-D-E-P-L-A-F-G-L-Y-T-V-F-V-M-V-E-M-E-E-K-E-G-G-M-D-P-I-E-E-A-M-N-A-L-E-N-V-E-S-A-E-V-V-E-L-S-L-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-E-H-L-K-Q-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-E-H-I-S-K-Q-A-W-G-D-W-L-K-K-Q-T-M-L-V-N-E-K-K-L-N-M-M-N-A-E-H-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-K-D-V-H-I-E-G-Y-V-P-P-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-A-S-H-S-L-G-E-K-I-L-I-K-L-I-R-F-Y-Q-I-V-I-S-P-L-I-G-P-R-C-R-F-V-P-T-C-S-C-Y-G-L-E-A-I-K-T-H-G-A-V-R-G-A-W-L-T-L-K-R-I-L-K-C-H-P-L-N-A-G-G-Y-D-P-V-P-P-K-S-D-N-H-S-K-E-N-K-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-N-T-V-F-C-K-K-F-Q-K-E-M-E-A-L-D-R-A-P-L-P-G-A-K-G-Q-E-I-L-Q-N-V-S-K-Q-A-W-Q-E-W-Q-H-L-Q-T-M-L-I-N-E-K-Q-L-N-L-M-Q-S-E-S-R-K-Y-V-M-E-Q-M-D-K-F-F-N-N-E-A-T-D-K-L-A-G-Y-V-D-P-D-D-I-K-E-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-T-S-F-L-F-E-G-K-E-V-E-I-E-G-F-V-P-E-K-D-Q-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-L-Q-W-L-A-T-T-L-I-R-G-Y-Q-V-F-I-S-P-I-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-K-V-H-G-T-A-K-G-C-W-F-A-L-K-R-I-L-K-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-C-S-C-G-K-N-R-A-G-E-G-A-P-K-R-Y-S-R-N-F-T-D-P-W-R-K-T-P-G-R-V-I-G-T-S-F-V-R-F-Y-Q-V-T-L-S-S-L-I-G-N-S-C-R-H-L-P-T-C-S-E-Y-A-Y-E-A-I-A-R-H-G-L-W-S-G-G-W-M-G-L-F-R-V-V-R-C-G-P-F-G-T-H-G-F-D-P-V-P-R-A-L-S-S-D-L-K-W-Y-L-P-W-R-Y-W-R-C-S-A-S"} +{"text": "### FUNCTION Stationary phase-essential protein not required for growth on nonfermentable carbon sources ### SEQUENCE -M-G-S-F-W-D-A-F-A-V-Y-D-K-K-K-H-A-D-P-S-V-Y-G-G-N-H-N-N-T-G-D-S-K-T-Q-V-M-F-S-K-E-Y-R-Q-P-R-T-H-Q-Q-E-N-L-Q-S-M-R-R-S-S-I-G-S-Q-D-S-S-D-V-E-D-V-K-E-G-R-L-P-A-E-V-E-I-P-K-N-V-D-I-S-N-M-S-Q-G-E-F-L-R-L-Y-E-S-L-R-R-G-E-P-D-N-K-V-N-R"} +{"text": "### FUNCTION Critical role in copper ### SEQUENCE -M-T-V-K-I-C-D-C-E-G-E-C-C-K-D-S-C-H-C-G-S-T-C-L-P-S-C-S-G-G-E-K-C-K-C-D-H-S-T-G-S-P-Q-C-K-S-C-G-E-K-C-K-C-E-T-T-C-T-C-E-K-S-K-C-N-C-E-K-C"} +{"text": "### FUNCTION Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions ### SEQUENCE -M-T-K-K-D-K-K-A-K-G-P-K-M-S-T-I-T-T-K-S-G-E-S-L-K-V-F-E-D-L-H-D-F-E-T-Y-L-K-G-E-T-E-D-Q-E-F-D-H-V-H-C-Q-L-K-Y-Y-P-P-F-V-L-H-D-A-H-D-D-P-E-K-I-K-E-T-A-N-S-H-S-K-K-F-V-R-H-L-H-Q-H-V-E-K-H-L-L-K-D-I-K-T-A-I-N-K-P-E-L-K-F-H-D-K-K-K-Q-E-S-F-D-R-I-V-W-N-Y-G-E-E-T-E-L-N-A-K-K-F-K-V-S-V-E-V-V-C-K-H-D-G-A-M-V-D-V-D-Y-K-T-E-P-L-Q-P-L-I"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-S-Q-S-R-W-S-I-V-L-I-F-A-L-F-I-F-G-S-T-G-V-N-A-F-F-N-F-G-H-H-Q-Q-Q-Q-Q-Q-Q-Q-Q-S-Y-E-D-Q-V-L-N-N-P-C-D-G-Y-L-C-P-D-T-L-T-C-V-A-Q-Q-K-D-C-P-C-P-F-P-K-S-Q-L-K-C-V-L-P-D-N-K-F-V-C-I-S-K-P-A-T-H-N-E-K-F-R-A-I-Y-D-D-P-V-K-G-P-K-A-K-N-K-G-F-R-D-C-G-W-V-S-D-A-Y-K-N-H"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-S-K-L-L-F-S-F-L-L-L-I-I-G-V-S-A-Q-F-Q-F-F-E-Q-M-F-N-N-G-G-Q-Q-H-H-H-H-Q-Q-P-Q-D-V-P-S-D-S-Q-W-Y-Q-D-N-Y-D-R-A-H-C-S-G-Y-L-C-P-G-T-L-S-C-V-A-V-P-H-H-C-P-C-A-H-P-V-Y-E-E-K-F-E-L-A-D-G-N-A-I-C-I-S-K-G-G-F-K-A-G-E-A-A-R-K-V-E-L-A-R-K-G-L-I"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-K-K-D-A-E-G-Q-D-F-Q-L-Y-P-G-E-I-G-K-R-I-Y-N-E-I-S-K-E-A-W-S-Q-W-I-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-I-E-D-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-Q-D-V-H-I-A-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-L-N-I-S-T-A-L-R-S-F-T-Q-R-Y-I-D-L-W-Q-Q-Q-T-G-H-L-P-A-S-K-D-L-Y-G-V-P-S-P-C-I-V-A-T-G-E-D-Q-V-F-W-Q-P-Q-A-F-L-P-E-A-T-L-T-N-I-E-R-A-L-E-I-Q-L-H-P-D-I-H-D-F-Y-T-Q-Q-Y-A-G-D-M-M-A-D-L-G-N-H-R-F-T-L-L-Q-V-W-S-E-D-D-F-I-R-L-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-L-F-L-A-T-T-S-S-E-M-T-M-A-S-L-C-N-V-S-G-N-V-V-L-E-Q-F-G-S-D-K-R-T-L-L-A-S-T-L-S-H-F-L-D-A-L-R-P-V-L-P-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-N-P-L-V-Y-F-S-S-S-S-E-N-S-H-R-F-V-E-K-L-Q-L-P-A-I-R-I-P-I-A-G-A-R-E-K-L-R-V-E-Q-P-Y-I-L-L-V-P-S-Y-G-G-G-S-P-V-G-A-V-P-I-Q-V-I-R-F-L-N-D-V-H-N-R-S-L-I-R-G-V-I-A-A-G-N-T-N-F-G-D-A-Y-C-L-A-G-D-I-I-S-H-K-C-Q-V-P-Y-L-Y-R-F-E-L-L-G-T-A-E-D-V-A-N-V-R-K-G-V-T-E-F-W-Q-R-Q-N"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-V-R-K-I-A-A-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-Y-K-D-I-A-H-P-I-N-T-E-T-R-E-K-I-Q-K-S-I-I-E-E-Y-E-R-A-K-M-E-E-E-S-S-E-K-V-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-L-L-I-C-I-I-K-M-Y-R-K-Y-I-S-P-L-K-R-P-S-C-R-F-Y-P-T-C-S-Q-Y-S-I-E-A-I-E-K-Y-G-A-L-K-G-T-L-I-S-I-K-R-I-L-K-C-H-P-F-N-E-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-E-I-V-E-M-S-L-L-L-D-F-Y-G-S-L-L-T-E-K-Q-N-K-I-M-D-L-Y-Y-N-N-D-Y-S-L-K-E-I-S-E-L-T-N-T-S-R-Q-A-V-H-D-I-V-K-R-C-H-K-A-L-L-Q-Y-E-E-K-L-H-M-M-E-R-F-I-N-L-E-N-S-K-E-K-L-L-N-M-L-N-K-V-T-K-E-N-I-K-E-I-D-H-I-K-K-Y-I-I-D-N-I"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-E-I-V-E-V-S-L-L-L-D-F-Y-G-S-L-L-T-E-K-Q-N-K-I-M-D-L-Y-Y-N-N-D-Y-S-L-K-E-I-S-E-L-T-N-T-S-R-Q-A-V-H-D-I-V-K-R-C-H-K-A-L-L-Q-Y-E-E-K-L-H-M-M-E-R-F-I-N-L-E-N-S-K-E-K-L-L-N-M-L-N-K-V-T-K-E-N-I-K-E-I-D-H-I-K-K-Y-I-I-D-N-I"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-V-R-K-I-A-A-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-Y-K-D-I-A-H-P-I-N-T-E-T-R-E-K-I-Q-K-S-I-I-E-E-Y-E-R-A-K-M-E-E-E-S-S-E-K-V-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-L-L-I-C-I-I-K-M-Y-R-K-Y-I-S-P-L-K-R-P-S-C-R-F-Y-P-T-C-S-Q-Y-S-L-E-A-I-E-K-Y-G-A-L-K-G-T-L-I-S-I-K-R-I-L-K-C-H-P-F-N-E-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-M-L-L-H-K-F-Q-A-R-Q-Q-L-V-A-E-L-K-Q-L-I-N-E-E-E-H-V-N-D-K-M-K-Q-V-V-E-D-I-E-K-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-T-H-G-A-L-K-G-F-W-L-T-L-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-F-A-L-S-C-I-K-F-Y-Q-N-Y-I-S-K-I-L-P-K-S-C-R-Y-Y-P-T-C-S-E-Y-A-V-W-E-F-K-N-N-D-I-F-S-A-L-L-A-T-L-A-R-I-L-R-C-N-Q-L-F-K-G-G-I-D-Y-P-V-I-R-K-R-F-G-S-F-S-I-F-K-R-M-E-F-S-N-I-D-F-W-F-V-P-C-K-N-S-K-F-Y-V-I-K-V-L-D-S-L-K-E-K-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-C-L-K-I-L-R-F-Y-Q-K-F-L-S-P-L-K-P-A-A-C-R-Y-Y-P-S-C-S-E-Y-A-L-W-Q-F-Q-K-K-N-F-F-L-A-F-L-S-T-F-F-R-I-L-R-C-N-P-F-F-K-G-G-F-D-Y-P-K-V-S-K-N-F-Y-P-M-N-L-C-F-K-P-M-F-L-A-K-K-Q-L-C-F-L-Y-I-P-Y-K-N-K-S-F-Y-L-I-K-I-I-F-K-R-T-N-Q"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-I-T-E-V-R-V-F-P-V-N-E-E-K-L-K-A-Y-V-T-I-T-L-D-D-C-F-V-V-R-D-L-K-V-I-H-G-N-T-G-L-F-I-A-M-P-A-K-R-R-K-D-G-T-F-K-D-I-A-H-P-L-N-T-E-T-R-E-R-M-E-R-T-I-L-A-E-Y-D-R-E-L-R-K-G-A-A-P-R-P-T-G-T-H-D-D"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-M-C-K-K-L-G-K-E-L-P-G-L-T-F-K-P-F-P-N-E-L-G-Q-R-I-Y-D-S-V-S-Q-D-A-W-K-L-W-L-E-H-F-K-M-I-M-N-E-Y-R-L-S-P-A-D-P-R-S-Q-E-I-L-Y-Q-Q-A-E-Q-F-F-F-S-E-G-A-Q-L-P-P-D-Y-R-P-P-R-S-K-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-R-R-A-L-V-F-L-V-R-V-Y-Q-R-L-V-S-P-L-L-P-P-A-C-R-F-Y-P-S-C-S-A-Y-A-A-T-A-L-E-R-H-G-A-L-K-G-S-A-L-A-A-R-R-L-L-R-C-H-P-F-H-P-G-G-I-D-P-V-P-E-S-E-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-V-I-L-K-L-I-R-F-Y-Q-K-Y-I-S-P-L-K-P-P-T-C-R-F-E-P-T-C-S-T-Y-T-Y-Q-A-V-E-R-F-G-I-L-K-G-L-L-L-G-F-W-R-V-L-R-C-N-P-I-S-K-G-G-H-D-P-V-P-T-E-F-Y-L-F-K-K-S-N-N-S-L-R-R-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-I-F-M-A-V-I-E-F-Y-Q-R-F-I-S-P-V-L-P-N-S-C-R-Y-Y-P-S-C-S-E-Y-S-L-H-E-F-K-F-N-S-F-F-G-A-F-F-A-T-V-L-R-I-L-R-C-N-P-L-F-R-G-G-I-D-Y-P-L-V-R-L-K-I-Q-H-Q-K-A-I-F-K-I-C-R-S-E-V-K-F-W-F-V-P-C-K-S-G-K-F-Y-V-I-K-S-F-K-K-E-K"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-D-Q-P-A-A-G-F-P-A-L-H-F-E-L-E-Q-P-D-R-Y-L-T-F-Q-G-I-D-F-E-G-N-M-R-R-V-L-A-H-L-Y-R-Y-I-D-D-P-A-H-G-N-A-F-W-D-R-F-K-A-R-L-Q-A-A-E-A-G-A-A-T-I-C-D-K-L-L-L-L-H-S-H-V-Y-Y-M-V-D-L-F-E-E-Q-E-D-E-I-A-L-A-D-L-K-T-L-E-E-E-C-F"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-T-R-L-I-Y-F-S-S-R-S-E-N-T-H-R-F-I-A-R-L-G-L-P-A-A-R-I-P-L-E-D-R-E-R-L-R-A-D-E-P-Y-I-L-V-V-P-T-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-A-G-N-R-N-F-G-E-G-F-C-R-A-G-D-I-I-A-H-K-C-Q-V-P-F-L-Y-R-F-E-L-M-G-T-G-Q-D-I-D-N-V-R-K-G-V-S-E-F-W-Q-R-Q-H"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-Q-R-D-A-E-G-Q-D-F-Q-L-Y-P-G-E-L-G-K-R-I-Y-N-E-I-S-K-E-A-W-A-Q-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-P-E-H-R-K-L-L-E-E-E-M-V-N-F-L-F-E-G-K-E-V-H-I-E-G-Y-T-P-P-E-Q-Q"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-Q-N-E-V-Q-Q-A-L-A-A-F-S-A-R-Y-C-E-A-W-R-Q-Q-R-G-S-L-P-V-S-E-E-Y-I-G-I-S-S-P-C-I-V-S-T-H-P-D-A-V-E-W-E-P-Q-P-F-T-P-E-D-S-L-G-A-V-E-K-A-L-D-I-V-I-Q-P-D-V-H-A-F-Y-A-S-Q-Y-A-G-D-M-A-A-R-Y-D-D-V-A-L-T-L-L-Q-A-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-I-F-I-A-T-L-D-S-E-L-D-V-I-S-L-C-N-L-T-G-E-V-V-Q-E-T-L-G-T-R-K-R-R-V-L-A-P-S-L-S-T-F-L-S-Q-L-T-P-L-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-A-R-L-K-K-E-G-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-E-A-W-A-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-D-P-E-H-R-K-Q-L-E-T-E-M-V-N-F-L-F-E-G-K-D-V-H-I-E-G-Y-T-P-P-S-E"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-T-Q-T-V-P-Q-A-L-Q-D-F-S-L-R-Y-Q-Q-A-W-Q-D-K-H-N-E-L-P-R-S-E-E-L-A-D-L-V-S-P-C-V-E-E-K-R-D-G-A-V-L-W-K-A-F-P-R-E-E-M-A-D-F-T-N-V-E-N-A-I-E-L-T-L-H-E-D-I-K-L-F-F-G-S-Q-Y-S-A-D-M-D-A-T-W-Q-G-N-E-L-T-L-L-Q-V-W-S-D-D-D-F-T-R-L-Q-E-N-I-L-G-H-L-V-T-Q-R-R-L-K-L-K-P-T-V-F-I-A-A-T-D-A-E-L-D-V-I-S-I-C-N-L-T-G-N-V-I-L-E-R-L-G-S-D-K-R-D-V-L-A-E-T-L-T-E-F-L-S-K-L-E-A-A-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-K-V-F-C-K-K-Y-H-Q-E-L-D-A-I-P-F-Q-P-L-P-G-E-L-G-K-K-I-H-N-E-I-S-N-K-A-W-Q-A-W-L-A-H-Q-T-I-L-I-N-E-Y-R-L-N-L-I-E-P-K-A-K-E-F-L-K-E-E-M-Y-K-F-L-F-E-G-K-E-E-K-P-E-Q-F-S-E-I"} +{"text": "### FUNCTION Chaperone protein which promotes assembly of the 20S proteasome May cooperate with psmg1-psmg2 heterodimers to orchestrate the correct assembly of proteasomes ### SEQUENCE -M-A-A-A-I-D-G-S-L-P-V-C-R-Q-S-A-A-L-I-D-G-V-H-T-D-F-L-A-S-W-Y-S-D-R-I-L-V-L-V-T-Q-F-Q-K-F-G-T-L-V-S-V-T-R-D-Q-P-V-A-R-P-D-Q-A-Q-G-G-T-D-S-H-T-F-T-T-K-V-L-M-G-D-D-L-P-I-W-H-V-Y-G-Q-Q-I-F-K-A-I-N-G-E-D-G-C-K-P-V-L-V-A-I-A-L-Q-N-H-S-P-E-I-L-K-C-I-L-G-Q-L-E-S-I-R-Q-V-Q-T-P"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-I-A-G-F-F-T-R-F-L-F-A-I-L-L-L-L-P-Y-S-Q-G-F-F-N-F-Q-G-N-Q-R-Q-Q-Q-Q-Q-H-H-Q-N-A-N-P-A-E-G-F-L-S-P-H-E-E-R-A-L-S-N-Q-C-P-G-Y-L-C-P-D-T-E-E-C-V-D-S-P-S-S-C-P-C-P-F-P-G-S-Q-L-K-C-S-L-P-D-G-T-F-V-C-I-S-K-P-A-T-D-N-E-D-I-N-R-K-Y-D-D-L-S-G-N-S-K-I-K-F-N-G-V-R-D-C-G-W-V-Y-E-M-A-V-K-G-F-S-T"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity ### SEQUENCE -M-L-S-F-S-Q-N-R-S-H-S-L-E-Q-S-L-K-E-G-Y-S-Q-M-A-D-L-N-L-S-L-A-N-E-A-F-P-I-E-C-E-A-C-D-C-N-E-T-Y-L-S-S-N-S-T-N-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-L-F-D-T-V-I-N-L-E-E-Q-I-G-S-L-Y-R-Q-L-G-D-L-K-Q-H-I-G-E-M-I-E-E-N-H-H-L-Q-L-E-N-K-H-L-R-K-R-L-D-D-T-T-E-Q-I-E-K-F-K-A-D-Q-K-E-T-K-T-Q-K-A-E-Q-S-D-I-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-N-V-H-Y-G-S-V-R-K-G-D-C-L-F-C-L-S-F-L-N-K-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-S-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-S-K-Q-K-S-Y-M-S-L-Y-Y-L-D-D-F-S-L-G-E-I-A-E-E-Y-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-Q-Y-E-E-K-L-L-L-F-K-K-F-Q-E-R-K-E-M-F-T-K-L-K-E-L-A-S-G-L-Q-E-E-E-K-M-T-A-L-I-E-A-L-E-K-L-D"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-V-Q-I-I-F-D-S-K-T-G-N-V-Q-R-F-V-N-K-T-D-F-Q-L-I-R-K-V-D-E-T-D-H-V-D-T-P-F-V-L-V-T-Y-T-T-N-F-G-Q-V-P-A-S-T-Q-S-F-L-E-K-Y-A-H-L-L-L-G-V-A-A-S-G-N-K-V-W-G-D-N-F-A-K-S-A-D-T-I-S-R-Q-Y-Q-V-P-I-L-H-K-F-E-L-S-G-T-S-K-D-V-E-L-F-T-Q-E-V-E-R-V-V-T-K-S-S-A-K-M-D-P-V-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-I-M-I-A-F-I-R-G-Y-Q-K-F-I-S-P-L-T-P-P-S-C-R-F-Y-P-T-C-S-Q-Y-G-I-E-A-V-K-T-H-G-A-L-K-G-G-W-L-T-L-K-R-I-L-K-C-H-P-F-H-P-G-G-V-D-P-V-P-D-K-K-Q-K-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-F-A-I-K-F-I-A-F-Y-Q-K-Y-I-S-I-L-L-P-K-S-C-R-Y-Y-P-T-C-S-Q-Y-A-I-W-E-F-Q-T-N-S-F-F-S-A-F-F-A-T-F-M-R-I-L-R-C-N-Q-L-F-K-G-G-I-N-Y-P-I-I-R-K-K-F-N-S-C-F-I-F-Q-K-S-D-T-K-N-V-N-F-W-F-I-P-C-Q-N-S-K-F-Y-V-V-K-V-L-D-K-L-K-E-K-N"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-A-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-A-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Makes mgtA transcription sensitive to intracellular proline levels Under low levels of proline this protein cannot be fully translated, and a stem loop forms which permits transcription of the downstream mgtA gene ### SEQUENCE -M-E-P-D-P-T-P-L-P-R-R-R-L-K-L-F-R"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-V-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-S-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-C-E-N-E-T-A-S-W-L-F-D-D-H-A-A-I-V-V-Q-R-A-L-R-L-R-Q-E-L-A-L-D-W-P-G-I-A-M-T-L-T-L-L-E-E-N-D-R-L-R-Q-E-N-R-L-L-I-Q-R-L-S-R-F-I-K-H-P"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-S-Q-A-L-T-A-F-T-T-R-Y-C-D-A-W-H-E-K-H-N-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-S-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-A-N-V-N-A-V-E-S-A-F-D-I-V-I-Q-S-A-V-H-A-F-Y-T-T-Q-F-A-G-D-M-Y-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-A-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-N-R-T-V-L-A-A-S-L-A-E-F-L-T-Q-L-K-P-L-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-Q-R-E-A-E-G-Q-D-F-Q-L-Y-P-G-E-L-G-K-R-I-Y-N-E-I-S-K-E-A-W-A-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-E-H-R-K-L-L-E-Q-E-M-I-N-F-L-F-E-G-K-D-V-H-I-E-G-Y-T-P-E-E-K-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-L-E-E-I-A-E-K-Y-P-K-D-S-F-L-Q-E-Q-I-A-T-L-S-S-I-D-N-R-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-R-E-I-F-D-A-L-D-D-F-S-Q-N-L-M-L-T-L-A-E-V-E-A-I-K-K-N-L-K-S-V-I-E-E-N-T-V-L-R-L-E-N-D-K-L-R-E-R-L-G-E-V-E-K-T-G-P-S-K-G-G-G-Q-G-R-E-N-L-E-R-I-Y-L-D-G-F-H-I-C-T-D-F-Y-G-Q-R-R-D-N-D-E-E-E-C-A-F-C-N-E-L-L-F-R-E"} +{"text": "### FUNCTION Plays a role in the assembly or stability of the cytochrome c oxidase complex ### SEQUENCE -M-V-S-G-K-R-I-A-D-V-G-Y-R-L-F-S-G-S-M-M-L-L-T-V-Y-G-G-Y-L-C-V-V-R-A-Q-R-Y-M-Q-R-K-K-Q-L-E-L-A-A-Q-S-E-N-T-A-S-E-I-I-K-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-W-L-F-K-Y-L-I-R-F-Y-Q-K-Y-L-T-I-L-S-F-G-S-C-R-Y-Y-P-T-C-S-Q-Y-A-L-W-Q-L-D-N-N-T-F-F-K-A-I-Y-F-T-I-L-R-I-L-K-C-N-Q-L-F-D-G-G-F-D-Y-P-I-I-K-L-K-K-N-Q-N-I-N-Y-N-K-I-K-I-V-Y-W-Y-V-P-L-K-N-G-K-Y-L-V-V-K-N-R-E-W-K-K-N-N-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-K-I-L-L-L-L-I-R-F-Y-Q-Y-F-I-S-P-L-L-G-N-N-C-R-F-H-P-T-C-S-E-Y-A-K-E-S-I-T-L-Y-G-S-L-K-G-L-W-R-A-F-K-R-I-I-K-C-Q-P-F-Y-N-G-T-V-L-Y-D-T-E-V-R-C-H-A-R-K-S-G-N-P-V-K-N-K-E-P-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-R-I-L-L-L-L-L-R-F-Y-Q-Y-F-I-S-P-L-L-S-N-N-C-R-F-H-P-T-C-S-E-Y-A-K-E-A-I-S-M-H-G-S-I-K-G-L-W-L-T-F-K-R-I-I-K-C-Q-P-F-C-D-G-G-Y-D-T-V-P-I-S-I-K-N-S-K-P-L-N-K-K-I"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-T-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-A-K-Q-K-S-Y-M-S-L-Y-Y-L-D-D-F-S-L-G-E-I-A-D-E-Y-E-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-Q-Y-E-E-K-L-L-L-F-K-K-F-K-E-R-K-E-L-L-K-K-M-R-E-L-V-A-D-S-A-Q-T-E-E-A-E-A-L-I-E-S-L-E-K-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-C-I-S-P-L-T-P-P-S-C-R-F-Y-P-T-C-S-N-Y-G-L-E-A-I-K-T-H-G-A-L-K-G-G-W-L-T-I-K-R-I-L-K-C-H-P-L-H-P-G-G-I-D-P-V-P-P-K-K-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-K-T-Q-S-P-L-Q-W-L-A-T-T-L-I-R-G-Y-Q-V-F-I-S-P-F-L-G-A-N-K-C-R-F-H-P-T-C-S-T-Y-A-I-E-A-I-R-L-H-G-F-A-K-G-S-W-L-A-A-R-R-I-L-K-C-H-P-L-H-P-G-G-I-D-P-V-P-P-K-K-H-R-C-N-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-K-K-E-S-E-G-L-G-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-V-S-K-E-A-W-A-L-W-Q-S-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-M-N-F-L-F-E-G-K-E-V-E-I-E-G-Y-V-P-Q-K-D-D-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-P-L-S-P-G-S-R-I-L-I-G-L-V-R-A-Y-Q-L-V-I-S-P-L-L-G-P-R-C-R-F-Q-P-T-C-S-H-Y-A-I-E-A-L-S-R-F-G-M-I-K-G-S-W-L-A-L-K-R-V-L-K-C-H-P-L-N-P-G-G-D-D-P-V-P-P-K-P-D-D-N-R-E-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-N-P-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-V-E-K-L-S-L-P-A-M-R-I-P-I-A-G-A-R-S-K-L-L-M-E-T-P-Y-I-L-I-V-P-S-Y-G-G-G-S-A-V-G-A-V-P-I-Q-V-I-R-F-L-N-D-P-Q-N-R-A-F-L-R-G-V-I-A-A-G-N-T-N-F-G-A-A-Y-G-I-A-G-D-I-I-A-K-K-C-Q-V-P-F-L-Y-R-F-E-L-L-G-T-T-Q-D-V-A-N-V-R-Q-G-V-T-A-F-W-Q-R-Q-N"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-Q-R-D-A-E-G-Q-D-F-Q-L-Y-P-G-E-V-G-K-R-I-Y-N-E-I-S-K-E-A-W-A-E-W-M-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-L-L-E-G-E-M-I-K-F-L-F-E-G-H-D-V-H-I-E-G-Y-T-P-P-S-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-K-I-L-L-L-I-V-K-F-Y-Q-Y-F-I-S-P-L-L-G-N-N-C-R-F-H-P-S-C-S-E-Y-A-K-E-A-I-T-I-Y-G-S-T-K-G-L-W-I-T-F-K-R-I-I-K-C-Q-P-F-C-N-G-G-Y-D-N-V-P-I-S-I-K-N-Y-K-S-L-N-K-K-I"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-R-I-L-L-L-L-L-T-F-Y-R-Y-F-I-S-P-L-L-G-G-N-N-C-R-F-Y-P-T-C-S-K-Y-A-K-E-A-L-N-T-H-G-G-I-K-G-L-W-L-I-F-K-R-I-I-K-C-Q-P-L-C-D-G-G-Y-D-P-V-P-P-T-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-N-K-E-A-E-G-L-G-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-V-S-K-E-A-W-A-L-W-Q-S-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-E-D-R-K-F-L-E-E-Q-M-V-N-F-L-F-E-G-K-D-V-E-I-E-G-Y-V-P-Q-K-D-D-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-K-T-Q-S-P-L-Q-W-L-A-T-T-I-I-R-G-Y-Q-L-L-I-S-P-M-M-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-R-L-H-G-V-V-K-G-C-W-F-A-G-K-R-I-L-R-C-H-P-L-H-P-G-G-E-D-P-V-P-N-K-K-H-R-C-D-K"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-R-A-S-P-T-P-W-L-S-R-A-E-P-Y-C-Q-R-E-S-P-M-N-L-L-T-T-T-P-A-G-D-R-Y-V-T-F-N-G-I-D-F-E-G-N-M-A-R-V-L-A-H-L-R-R-Y-I-D-D-P-R-T-G-N-A-F-W-D-R-F-K-A-R-L-A-A-A-E-S-G-G-N-A-F-Q-D-K-L-L-L-L-H-S-H-V-Y-Y-M-G-D-L-F-E-D-Q-E-D-E-A-A-L-A-D-L-R-K-L-E-E-E-C-F"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-P-L-A-W-L-L-S-L-P-V-R-A-Y-R-L-I-F-S-P-W-V-G-F-N-C-R-Y-D-P-T-C-S-A-Y-A-M-E-A-L-R-K-H-G-G-V-K-G-G-W-L-T-L-R-R-I-L-R-C-H-P-W-G-G-T-G-V-D-D-V-P-D"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-V-T-D-V-R-I-R-R-V-T-A-E-G-K-M-K-A-I-V-S-V-T-F-D-D-E-F-V-V-H-D-I-K-I-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-M-G-E-G-D-F-R-D-I-A-H-P-I-N-S-S-T-R-T-K-L-Q-D-A-I-F-A-E-Y-E-K-M-S-D-M-E-E-E-A-A-N-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-R-L-C-I-F-L-I-Q-I-Y-R-K-Y-I-S-P-L-K-R-P-S-C-R-F-H-P-T-C-S-A-Y-S-M-A-A-Y-E-R-Y-G-F-F-K-G-T-Y-L-T-L-K-R-I-L-K-C-H-P-F-H-P-G-G-Y-D-P-L-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-I-L-I-F-I-V-R-I-Y-Q-T-L-I-S-P-L-F-P-P-S-C-R-Y-Y-P-T-C-S-N-Y-M-I-D-A-L-K-K-H-G-P-I-L-G-L-I-M-G-I-S-R-T-L-R-C-N-P-F-V-R-G-G-V-D-P-V-P-D-N-F-T-V-F-R-N-P-H-P-E-R-Y-E-D-E-I-I-A-S-K-F-H-S-N-S-K"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-A-T-V-I-A-K-V-K-V-M-P-T-S-P-E-V-E-K-E-A-L-K-E-T-L-K-E-L-V-E-K-N-D-A-K-C-R-G-V-S-D-E-P-L-A-F-G-L-Y-T-V-F-V-M-V-E-M-E-E-K-E-G-G-M-D-P-I-E-E-A-M-N-A-L-E-N-V-E-S-A-E-V-V-E-L-S-L-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-Q-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-N-V-S-K-E-A-W-Q-G-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-T-E-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-K-I-L-L-A-L-I-R-L-Y-Q-R-F-S-R-Y-T-P-P-S-C-I-Y-T-P-T-C-S-H-Y-G-Y-Q-A-I-A-K-Y-G-A-F-K-G-T-W-L-T-L-K-R-I-A-R-C-H-P-W-A-Q-G-G-E-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-V-L-K-S-I-D-F-Y-R-K-H-I-S-P-A-T-P-P-K-C-I-Y-L-P-T-C-S-S-Y-T-Y-E-A-V-E-K-F-G-V-F-K-G-L-Y-L-G-F-R-R-F-I-R-C-N-P-L-H-K-G-G-Y-D-P-V-P-E-K-F-S-F-F-V-H-K-Q-G-K-N-K-Q-H-R-R-S-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-H-C-I-K-L-G-V-D-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-K-R-I-F-E-G-V-S-K-Q-A-W-A-D-W-L-K-H-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-Q-Y-L-A-R-Q-M-E-N-H-F-F-G-G-G-A-D-A-A-A-G-Y-V-P-P-T-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-A-T-L-L-L-A-L-I-R-A-Y-Q-M-T-L-S-R-L-I-V-A-L-M-G-P-V-C-R-F-E-P-S-C-S-R-Y-A-A-A-C-I-V-D-H-G-A-L-R-G-S-L-L-S-L-K-R-L-C-R-C-H-P-F-H-P-G-G-F-D-P-P-P-P-P-R-L-H-R-A-A-A-A-R-M-P-R-Q-R-D-A-D-P-R-D-T-T-R-C-S-S-T-G-A-E-L-A-S-H-A-S-S-P-C-R-A-G-F-S-G-R-V-T-L-M-D"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-T-E-Q-I-D-R-Y-V-S-F-R-N-V-E-W-E-R-R-T-A-E-V-F-A-L-L-Q-P-H-F-D-G-S-T-S-P-F-W-D-Y-F-L-R-Q-R-V-I-A-H-A-Q-G-L-D-D-L-R-V-L-H-N-F-L-P-T-L-K-D-L-L-E-E-L-D-D-E-R-T-L-S-R-L-E-E-L-E-V-L-C-M"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-G-L-I-V-Y-Y-S-S-A-T-G-N-T-E-H-F-V-S-Q-L-G-Q-R-L-F-K-I-D-K-R-K-P-S-A-F-V-G-E-P-Y-V-L-V-V-P-T-Y-A-D-G-E-G-R-G-A-V-P-K-A-V-I-H-F-L-N-E-A-E-N-R-K-L-I-R-G-V-I-G-S-G-N-R-N-F-G-R-Y-Y-S-L-A-S-K-I-I-A-E-K-C-G-V-P-C-L-Y-R-F-E-L-R-G-T-D-E-D-V-I-C-V-K-K-G-L-E-R-F-W-K-Q-L-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-S-Q-F-Q-Q-K-K-M-T-R-N-Y-T-G-A-W-Q-K-T-P-G-R-L-L-G-I-F-L-I-R-F-Y-Q-I-T-L-S-S-L-I-G-N-Q-C-R-H-A-P-T-C-S-E-Y-I-Y-E-A-I-A-R-H-G-L-W-A-G-A-W-M-G-L-F-R-I-M-R-C-G-P-F-G-T-D-G-F-D-P-V-P-P-S-L-G-H-S-C-C-F-Y-K-P-W-R-Y-W-K-I-S-D-K-H-N-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Y-K-Q-I-V-H-A-I-G-K-A-I-Q-T-L-L-L-G-L-I-K-S-Y-R-Y-L-I-S-P-V-L-M-S-S-C-R-F-Y-P-S-C-S-C-Y-A-E-T-A-L-K-R-F-G-V-I-K-G-S-G-L-T-V-W-R-L-L-R-C-H-P-F-H-P-G-G-V-D-F-V-P-E-K-S-N-E-M-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-R-I-I-C-Q-K-L-G-K-E-A-D-A-L-N-Y-S-P-Y-P-G-E-L-G-E-R-I-Y-N-H-I-S-E-Q-A-W-Q-A-W-L-S-H-Q-T-M-L-I-N-E-Y-R-L-S-L-I-D-P-K-A-R-Q-F-L-E-Q-E-M-I-N-F-L-F-G-T-G-S-E-K-P-A-G-Y-T-S-E-K-E"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-T-K-Q-I-I-K-G-I-I-I-E-R-S-S-P-L-K-I-D-E-L-S-Q-A-V-H-L-R-R-E-I-I-I-E-M-V-E-H-R-L-I-E-P-E-G-S-S-P-T-S-W-K-F-D-N-V-C-L-K-R-A-K-I-A-A-S-F-Y-R-D-L-E-I-N-M-P-G-I-A-I-A-L-D-L-L-D-K-I-E-H-L-E-Q-R-L-R-T-L-E-R-F-E-N-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-I-V-K-L-Y-R-K-Y-I-S-P-M-K-R-V-P-T-C-R-F-T-P-T-C-S-E-Y-A-L-E-A-L-Q-R-Y-G-A-I-R-G-S-Y-L-A-V-R-R-I-L-K-C-H-P-F-H-K-G-G-F-D-P-V-P"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-V-R-R-V-S-K-E-G-K-M-K-A-V-V-S-I-T-L-D-N-E-F-V-V-H-D-I-K-V-I-E-G-E-K-G-L-F-I-A-M-P-S-R-K-A-G-D-G-E-Y-R-D-I-A-H-P-I-N-S-I-T-R-D-K-I-Q-S-I-I-L-E-K-Y-E-L-A-A-L-E-G-N-I-E-E-A-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-L-Q-W-L-A-T-T-L-I-R-G-Y-Q-V-F-I-S-P-I-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-K-V-H-G-T-A-K-G-C-W-F-A-L-K-R-I-L-K-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-T-S-F-L-F-E-G-K-E-V-E-I-E-G-F-V-P-E-K-D-Q-D"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-F-C-V-K-L-N-K-E-A-E-G-M-K-F-P-P-L-P-N-E-L-G-K-R-I-F-E-N-V-S-Q-E-A-W-A-A-W-T-R-H-Q-T-M-L-I-N-E-N-R-L-S-L-A-D-P-R-A-R-E-Y-L-A-Q-Q-M-E-Q-Y-F-F-G-D-G-A-D-A-V-Q-G-Y-V-P-Q"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-F-L-L-S-K-L-L-L-G-L-I-R-F-Y-Q-Y-C-I-S-P-L-I-P-P-R-C-R-Y-T-P-T-C-S-Q-Y-A-V-E-A-V-K-K-Y-G-A-F-K-G-G-R-L-A-I-K-R-I-A-R-C-H-P-F-G-G-H-G-H-D-P-V-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-L-I-V-Y-F-S-S-R-S-G-N-T-H-R-F-V-E-R-L-G-V-R-S-S-R-I-P-L-E-A-S-G-A-L-Q-V-R-E-P-F-V-L-V-T-P-T-Y-G-G-G-S-T-K-G-A-V-P-N-P-V-I-R-F-L-N-D-A-D-N-R-A-L-I-R-G-V-I-A-A-G-N-S-N-F-G-E-A-F-C-I-A-G-N-I-I-S-A-K-C-G-V-P-Y-L-Y-R-F-E-L-L-G-T-A-E-D-V-G-N-V-R-N-G-M-E-Q-F-W-T-R-Q-T-Q-A"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-R-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-H-V-R-K-G-V-N-E-F-W-R-Q-Q-T-R-S-A"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-N-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-Q-L-L-L-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-R-R-Y-C-G-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-V-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-R-L-S-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-I-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-H-R-I-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-K-G-V-N-E-F-W-Q-Q-L-S-R-S-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Y-K-Q-I-V-H-A-I-G-K-A-I-Q-T-L-L-L-G-L-I-K-S-Y-R-Y-L-I-S-P-V-L-M-S-S-C-R-F-Y-P-S-C-S-C-Y-A-E-T-A-L-K-R-F-G-V-I-K-G-S-G-L-T-V-W-R-L-L-R-C-H-P-F-H-P-G-G-V-D-F-V-P-E-K-S-N-E-M-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-R-I-I-C-Q-K-L-G-K-E-A-D-A-L-N-Y-S-P-Y-P-G-E-L-G-E-R-I-Y-N-H-I-S-E-Q-A-W-Q-A-W-L-S-H-Q-T-M-L-I-N-E-Y-R-L-S-L-I-D-P-K-A-R-Q-F-L-E-Q-E-M-I-N-F-L-F-G-I-G-S-E-K-P-A-G-Y-T-S-E-K-E"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-T-K-Q-I-I-K-G-I-I-I-E-R-S-S-P-L-K-I-D-E-L-S-Q-A-V-H-L-R-R-E-I-I-I-E-M-V-E-H-R-L-I-E-P-E-G-S-S-P-T-S-W-K-F-D-N-V-C-L-K-R-A-K-I-A-A-S-F-Y-R-D-L-E-I-N-M-P-G-I-A-I-A-L-D-L-L-D-K-I-E-H-L-E-Q-R-L-R-T-L-E-R-F-E-N-Q-E"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-I-T-D-V-R-V-R-H-V-S-S-D-S-R-L-K-G-V-V-T-I-T-F-E-D-A-F-V-V-H-D-I-R-V-I-E-G-E-N-G-L-F-V-A-M-P-S-K-K-M-P-N-G-G-F-R-D-I-A-H-P-I-H-A-D-M-R-K-Q-I-E-D-S-I-I-K-A-Y-K-E-T-L-D-A-E-A-T-A-S-V-E-E"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-L-N-I-S-T-A-L-R-S-F-T-Q-R-Y-I-D-L-W-Q-Q-Q-T-G-H-L-P-A-S-K-E-L-Y-G-V-P-S-P-C-I-V-E-T-G-E-D-Q-V-F-W-Q-P-Q-A-F-L-P-E-A-T-L-T-N-I-E-R-A-L-E-I-Q-L-H-P-D-I-H-D-F-Y-T-Q-Q-Y-A-G-D-M-M-A-D-L-G-N-H-R-F-T-L-L-Q-V-W-S-E-D-D-F-I-R-L-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-L-F-L-A-T-T-S-S-E-M-T-M-A-S-L-C-N-V-S-G-N-V-V-L-E-Q-F-G-S-D-K-R-T-L-L-A-S-T-L-S-H-F-L-D-A-L-R-P-V-L-P-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-K-K-D-A-E-G-Q-D-F-Q-L-Y-P-G-E-I-G-K-R-I-Y-N-E-I-S-K-E-A-W-S-Q-W-I-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-I-E-D-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-Q-D-V-H-I-A-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-T-F-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-N-S"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-E-K-K-D-I-F-A-S-V-S-S-M-E-E-Q-I-G-H-L-Y-K-Q-L-G-E-L-K-Q-H-L-A-E-L-L-E-E-N-Q-H-I-K-M-E-N-E-N-L-R-H-R-F-E-E-V-Q-N-K-E-K-Q-K-T-Q-K-R-K-E-M-K-A-K-T-D-I-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-N-L-H-Y-G-S-V-R-K-E-G-D-C-L-F-C-L-S-F-L-N-K-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-D-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-L-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-R-W-L-L-L-K-L-I-R-F-Y-Q-V-A-I-S-P-W-T-P-P-S-C-I-Y-T-P-T-C-S-H-Y-G-Y-E-A-I-K-K-Y-G-A-L-R-G-G-W-M-T-V-K-R-I-A-R-C-H-P-F-A-R-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-L-I-V-Y-F-S-S-R-S-G-N-T-H-R-F-V-E-R-L-G-V-R-S-S-R-I-P-L-E-A-S-G-A-L-Q-V-R-E-P-F-V-L-V-T-P-T-Y-G-G-G-S-T-K-G-A-V-P-N-P-V-I-R-F-L-N-D-A-D-N-R-A-L-I-R-G-V-I-A-A-G-N-S-N-F-G-E-A-F-C-I-A-G-N-I-I-S-A-K-C-G-V-P-Y-L-Y-R-F-E-L-L-G-T-A-E-D-V-G-N-V-R-N-G-M-E-Q-F-W-T-R-Q-T-Q-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-S-R-I-S-S-F-F-R-G-L-V-H-L-Y-R-W-A-I-S-P-F-L-G-A-P-C-R-F-F-P-T-C-S-E-Y-A-L-V-A-L-K-K-H-P-L-R-K-S-L-F-L-I-A-K-R-L-L-K-C-G-P-W-C-I-G-G-I-D-L-V-P-R-T-S-V-E-E-Y-L-S-S-P-T-P-L-A-E-S-P-D-D-R-T-V-P-H-T-Q-E-T-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-S-R-I-S-S-F-F-R-G-L-V-H-L-Y-R-W-A-I-S-P-F-L-G-A-P-C-R-F-F-P-T-C-S-E-Y-A-L-V-A-L-K-K-H-P-L-R-K-S-L-F-L-I-A-K-R-L-L-K-C-G-P-W-C-I-G-G-I-D-L-V-P-R-T-S-V-E-E-Y-L-S-S-P-T-P-L-A-E-S-P-D-D-R-T-V-P-H-T-Q-E-T-S"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-E-Y-L-K-Q-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-S-I-S-K-Q-A-W-S-E-W-I-K-K-Q-T-M-L-V-N-E-K-K-L-S-M-M-N-A-E-H-R-K-L-L-E-T-E-M-V-N-F-L-F-E-G-K-E-V-Q-I-E-G-Y-V-P-V-E-Q-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-R-I-L-L-L-L-L-R-F-Y-Q-Y-F-I-S-P-L-L-G-N-N-C-R-F-H-P-T-C-S-E-Y-A-K-E-A-I-S-M-H-G-S-I-K-G-L-W-F-T-F-K-R-I-I-K-C-Q-P-F-C-D-G-G-Y-D-T-V-P-I-S-I-K-N-S-K-P-L-N-K-K-I"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-G-I-F-I-G-L-I-E-G-Y-R-R-F-I-S-P-L-F-P-P-S-C-R-F-Q-P-T-C-S-Q-Y-A-M-E-A-I-D-R-F-G-V-L-R-G-S-W-L-A-I-K-R-I-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P-P-C-H-H-K-H-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-D-D-D-F-L-F-M-T-L-L-Y-D-F-Y-G-A-L-L-T-D-K-Q-R-E-I-F-E-M-Y-Y-L-N-D-Y-S-L-G-E-I-S-E-L-L-D-I-S-R-Q-G-V-Y-D-T-L-K-R-A-E-S-S-L-E-F-F-E-E-K-L-G-L-V-K-R-H-Q-E-I-M-N-K-L-D-K-I-K-K-G-I-E-I-I-R-E-R-E-R-D-P-E-I-L-K-I-I-E-E-I-A-R-E-I-E-E-L-N-L"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-I-T-D-V-R-V-R-K-L-N-E-E-G-K-M-K-A-V-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-E-G-E-F-K-D-I-A-H-P-I-N-S-D-T-R-N-K-L-Q-S-A-I-L-K-E-Y-E-K-A-K-E-Q-E-A-A-H-K-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-V-V-I-F-L-I-K-L-Y-Q-R-Y-I-S-P-M-K-P-R-S-C-R-F-Y-P-T-C-S-Q-Y-S-I-E-A-I-S-K-Y-G-L-L-K-G-G-I-M-S-I-W-R-I-L-R-C-N-P-F-N-P-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-V-V-I-F-L-I-K-L-Y-Q-R-Y-I-S-P-M-K-P-R-S-C-R-F-Y-P-T-C-S-Q-Y-S-I-E-A-I-S-K-Y-G-L-L-K-G-G-I-M-S-I-W-R-I-L-R-C-N-P-F-N-P-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-D-D-D-F-L-F-M-T-L-L-Y-D-F-Y-G-A-L-L-T-D-K-Q-R-E-I-F-E-M-Y-Y-L-N-D-Y-S-L-G-E-I-S-E-L-L-D-I-S-R-Q-G-V-Y-D-T-L-K-R-A-E-S-S-L-E-F-F-E-E-K-L-G-L-V-K-R-H-Q-E-I-M-N-K-L-D-K-I-K-K-G-I-E-I-I-R-E-R-E-R-D-P-E-I-L-K-I-I-E-E-I-A-R-E-I-E-E-L-N-P"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-I-T-D-V-R-V-R-K-L-N-E-E-G-K-M-K-A-V-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-E-G-E-F-K-D-I-A-H-P-I-N-S-D-T-R-N-R-L-Q-S-A-I-L-K-E-Y-E-K-A-K-E-Q-E-A-A-H-K-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-M-C-R-K-Y-Q-E-E-L-P-G-L-E-R-P-P-Y-P-G-A-K-G-Q-D-I-F-E-H-I-S-Q-K-A-W-A-D-W-Q-K-H-Q-T-M-L-I-N-E-K-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-A-E-M-D-K-F-F-A-G-E-E-Y-A-Q-A-E-G-Y-V-P-P-A-E"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-S-S-T-L-I-V-Q-L-D-M-R-T-L-C-Q-E-A-D-V-T-A-D-C-V-I-E-I-V-E-H-G-I-V-E-P-S-G-R-T-P-E-D-W-L-F-D-D-Q-A-P-L-L-T-R-R-A-A-K-L-H-Q-E-L-E-L-E-W-E-G-V-A-L-A-L-E-L-L-Q-E-V-Q-Q-L-R-S-E-N-S-M-L-R-Q-R-L-G-R-F-T-Q-M"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -P-A-P-E-S-N-F-V-R-D-P"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -S-P-S-L-D-D-E-R-N-D-N-F-V-R-L"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -P-V-P-D-S-S-F-L-R-D-P"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -A-D-Y-L-Q-L-A-R-A"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -P-A-A-S-E-S-G-F-R-R-D-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-V-L-T-S-V-V-L-A-P-R-N-A-A-I-A-V-I-G-L-Y-R-R-I-V-S-P-L-Y-G-D-V-C-R-Y-Y-P-S-C-S-A-Y-G-L-E-A-V-Q-E-H-G-L-I-R-G-G-G-L-A-V-W-R-V-C-R-C-H-P-W-A-E-G-G-I-D-D-V-P-A-R-Q-V-Q-Q-Y-R-R-T-R-Y-G-F-V-V-A-P-S-H-G-K-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-Q-Y-Q-Q-C-D-T-E-G-L-D-F-A-P-Y-P-G-E-L-G-Q-R-I-F-A-Q-I-G-K-A-G-W-Q-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-D-P-K-H-R-A-F-L-E-A-E-L-Q-K-F-L-F-E-R-N-A-D-K-P-E-G-Y-V-D-P-L-G-E-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Y-H-W-Q-V-I-G-R-L-L-I-A-L-L-R-F-Y-K-R-F-I-S-P-L-L-G-P-R-C-R-F-A-P-S-C-S-E-Y-A-M-T-A-I-A-R-F-G-P-L-R-G-S-W-L-A-A-R-R-L-G-R-C-H-P-F-H-P-G-G-F-D-P-V-P-D-A-P-A-S-S-P-S-S-C-R-C-K-G-P-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-K-V-M-I-F-L-I-K-F-Y-Q-K-A-I-S-P-Y-L-G-Q-G-K-C-K-Y-Y-P-T-C-S-Q-Y-A-L-E-A-F-K-K-K-P-F-F-K-A-L-G-L-T-I-W-R-I-L-R-C-N-P-F-S-K-G-G-Y-D-P-L-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-R-L-F-L-V-L-I-F-L-Y-K-K-L-L-S-P-F-L-P-P-S-C-R-F-T-P-S-C-S-E-Y-A-K-Q-A-F-E-T-Y-P-W-Y-K-A-F-V-L-S-V-V-R-I-S-K-C-H-P-Y-H-E-G-G-H-D-P-L-P-K-S-Y-N-K-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-R-L-F-L-V-L-I-F-L-Y-K-K-L-L-S-P-F-L-P-P-S-C-R-F-T-P-S-C-S-E-Y-A-K-Q-A-F-E-T-Y-P-W-Y-K-A-F-V-L-S-V-V-R-I-S-K-C-H-P-Y-H-E-G-G-H-D-P-L-P-K-S-Y-N-K-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-F-Y-E-R-T-V-D-L-G-L-K-A-Y-K-T-T-L-S-P-F-I-G-R-Q-C-R-Y-L-P-T-C-S-E-Y-A-A-Q-A-L-K-D-H-G-P-L-K-G-S-W-L-A-V-G-R-I-C-R-C-N-P-L-G-G-S-G-Y-D-P-P-P-P-P-K-T-P-R-K-W-K-C-E-E"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-T-I-T-D-V-R-V-R-K-V-N-L-E-G-K-M-K-A-I-V-S-V-T-F-D-N-A-F-V-V-H-D-V-K-V-V-E-G-Q-K-G-L-F-V-A-M-P-S-R-R-T-P-E-G-E-Y-R-D-I-A-H-P-I-S-A-K-A-R-E-Q-I-S-V-A-V-L-N-A-Y-Q-E-A-L-A-S-A-I-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-N-K-E-A-E-G-L-G-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-V-S-K-E-A-W-A-L-W-Q-S-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-V-N-F-L-F-E-G-K-D-V-E-I-E-G-Y-V-P-Q-K-D-D-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-K-T-Q-S-P-L-Q-W-L-A-T-T-I-I-R-G-Y-Q-L-L-I-S-P-M-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-R-L-H-G-F-V-K-G-C-W-F-A-A-K-R-I-L-R-C-H-P-L-H-P-G-G-E-D-P-V-P-N-K-K-H-R-C-D-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-K-V-L-C-K-K-Y-N-E-E-L-D-A-I-P-F-Q-P-L-P-G-E-L-G-K-K-I-H-S-E-I-S-N-K-A-W-Q-A-W-L-A-H-Q-T-I-L-I-N-E-Y-R-L-N-L-I-E-P-K-A-K-E-F-L-K-E-E-M-Q-K-F-L-F-E-N-K-E-D-K-P-E-Q-F-N-E-I"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -P-A-P-E-S-S-F-I-R-D-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-L-P-R-R-A-A-H-A-A-I-R-A-Y-Q-L-T-L-S-G-L-V-G-R-Q-C-R-H-W-P-S-C-S-A-Y-A-D-E-A-I-Q-R-H-G-L-W-A-G-G-W-M-G-L-A-R-I-C-R-C-G-P-F-G-T-H-G-I-D-L-V-C-E-A-L-P-E-G-A-A-W-H-R-P-W-A-Y-G-R-W-R-G-V-N-A-P-A-P-L-G-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-E-T-S-H-S-F-G-A-K-V-L-I-G-A-I-R-I-Y-Q-L-M-I-S-P-L-I-G-P-R-C-R-F-V-P-T-C-S-C-Y-G-I-Q-A-V-K-T-H-G-V-V-K-G-S-W-L-T-V-K-R-I-L-K-C-H-P-F-N-V-G-G-Y-D-P-V-P-P-K-I-N-N-N-K-E-N-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-N-V-F-C-T-Y-L-N-Q-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-Q-A-W-A-E-W-M-K-K-Q-T-M-L-V-N-E-K-K-L-N-M-M-N-S-E-H-R-Q-L-L-E-Q-E-M-T-N-F-L-F-E-G-K-D-V-H-I-E-G-Y-V-P-P-T-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-R-I-L-R-W-F-I-R-L-Y-Q-I-A-I-S-P-L-L-G-P-R-C-R-Y-I-P-T-C-S-Q-Y-A-L-E-A-L-Q-T-H-G-A-I-K-G-V-W-L-S-S-K-R-I-C-R-C-H-P-W-G-G-S-G-Y-D-P-V-P-P-K-A-I-R-F-I-S-F-H-Q-I-D-S-Q-T-H-H-V-A-V-P-F-R-D-R-L-M-K-Q-N-L-S-N-H-L-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-Q-V-F-C-R-K-Y-Q-K-E-M-E-G-L-D-F-A-P-F-P-G-A-K-G-Q-E-F-F-E-N-V-S-K-Q-A-W-Q-E-W-L-Q-H-Q-T-T-L-I-N-E-K-R-L-N-V-F-E-P-E-A-K-K-F-L-E-E-Q-R-E-K-F-F-N-N-D-E-S-V-E-K-A-E-G-W-K-P-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-Q-V-F-C-R-K-Y-Q-M-E-M-E-G-L-D-F-A-P-F-P-G-A-K-G-Q-E-F-F-E-N-V-S-K-Q-A-W-Q-E-W-L-Q-H-Q-T-T-L-I-N-E-K-R-L-N-V-F-E-P-E-A-K-K-F-L-E-E-Q-R-E-K-F-F-N-N-D-E-S-V-E-K-A-E-G-W-K-P-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-R-I-L-R-W-F-I-R-L-Y-Q-I-A-I-S-P-L-L-G-P-R-C-R-Y-I-P-T-C-S-Q-Y-A-L-E-A-L-Q-T-H-G-A-I-K-G-V-W-L-S-S-K-R-I-C-R-C-H-P-W-G-G-S-G-Y-D-P-V-P-L-K-A-I-R-F-I-S-F-H-Q-I-D-S-Q-T-H-H-V-A-V-P-F-R-D-R-L-M-K-Q-N-L-S-N-H-L-G"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-L-S-S-W-V-R-C-L-G-A-L-L-F-L-A-S-V-A-Q-A-Q-F-Q-F-F-E-H-M-F-G-G-G-H-Q-E-H-H-Q-Q-N-T-Q-N-S-A-S-D-S-A-R-Y-Q-Q-L-W-E-G-T-N-C-N-K-Y-L-C-P-G-T-L-A-C-V-D-F-P-H-H-C-P-C-A-H-P-N-V-E-D-K-V-E-L-G-E-G-S-A-V-C-I-S-K-G-G-Y-K-P-G-E-A-A-R-K-I-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-N-K-N-K-R-W-Y-L-I-A-L-Y-D-I-Y-Q-G-L-L-T-T-K-Q-C-E-Y-F-N-L-H-Y-F-K-D-L-S-F-S-E-I-A-E-L-K-E-I-S-K-S-A-I-S-D-C-L-N-K-V-C-D-Q-L-L-K-Y-E-Q-A-L-L-I-Y-E-K-N-K-K-R-N-D-L-Y-T-L-I-N-D-S-E-L-V-K-K-L-K-D-I"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-A-L-F-L-I-K-C-Y-K-F-I-S-Q-F-L-P-S-I-C-R-F-Q-P-S-C-S-T-Y-A-Y-Q-A-I-E-T-Y-G-F-F-K-G-S-L-L-T-F-K-R-I-I-R-C-R-P-F-C-A-G-G-F-D-P-V-P-L-P-K-K-K-I"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-V-T-D-V-R-I-R-K-V-L-D-G-G-K-M-K-A-I-V-S-V-T-L-D-D-A-F-V-V-H-D-I-K-I-V-E-G-Q-N-G-L-F-V-A-M-P-S-R-R-T-P-N-G-E-F-R-D-I-A-H-P-I-N-A-S-A-R-A-R-I-Q-N-A-V-L-E-A-Y-E-H-R-D-A-A-E-F"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-R-P-Q-K-L-A-I-G-L-I-K-G-Y-Q-V-A-I-S-P-F-F-P-S-T-C-R-F-Y-P-T-C-S-E-Y-A-V-Q-A-I-G-K-Y-G-L-M-R-G-G-L-R-A-V-R-R-V-L-R-C-H-P-F-S-P-G-G-Y-D-P-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-P-V-R-F-Y-Q-R-F-I-S-P-V-F-P-P-S-C-R-F-E-L-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-F-K-G-V-L-M-G-L-A-R-I-L-R-C-H-P-W-S-K-T-G-K-D-P-V-P-D-H-F-S-L-K-R-N-Q-E-G-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-L-F-D-A-L-D-D-F-S-Q-Q-L-L-V-T-L-A-D-V-E-A-I-K-K-N-L-K-S-L-V-E-E-N-T-A-L-R-L-E-N-S-K-L-R-E-R-L-G-E-V-E-A-D-A-P-V-K-A-K-H-V-R-E-S-V-R-R-I-Y-R-D-G-F-H-V-C-N-D-F-Y-G-Q-R-R-E-Q-D-E-E-C-M-F-C-D-E-L-L-Y-R-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-Q-I-L-E-R-Y-P-K-D-N-F-L-Q-E-Q-I-E-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-V-R-K-I-A-A-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-Y-K-D-I-A-H-P-I-N-T-E-T-R-E-K-I-Q-K-S-I-I-E-E-Y-E-R-A-K-M-E-E-E-S-S-E-K-V-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-L-L-I-C-I-I-K-M-Y-R-K-Y-I-S-P-L-K-R-P-S-C-R-F-Y-P-T-C-S-Q-Y-S-L-E-A-I-E-K-Y-G-A-L-K-G-T-L-I-S-I-K-R-I-L-K-C-H-P-F-N-K-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-E-I-V-E-M-S-L-L-L-D-F-Y-G-S-L-L-T-E-K-Q-N-K-I-M-D-L-Y-Y-N-N-D-Y-S-L-K-E-I-S-E-L-T-N-T-S-R-Q-A-V-H-D-I-V-K-R-C-H-K-A-L-L-Q-Y-E-E-K-L-H-M-M-E-R-F-I-N-L-E-N-S-K-E-K-L-L-N-M-L-N-K-V-T-K-E-N-I-K-E-I-D-H-I-K-K-Y-I-I-D-N-I"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-A-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-S-S-T-L-I-V-Q-L-D-M-R-T-L-C-Q-E-A-D-I-T-A-D-Y-V-V-E-I-V-E-H-G-I-V-E-P-S-G-R-T-P-E-E-W-L-F-D-D-Q-A-P-L-L-A-R-R-A-A-K-L-H-Q-E-L-E-L-E-W-E-G-V-A-L-A-L-E-L-L-Q-E-V-Q-Q-L-R-S-E-N-S-M-L-K-Q-R-L-G-R-F-T-Q-M"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-M-C-R-K-Y-K-E-Q-L-P-G-L-E-R-P-P-Y-P-G-A-K-G-Q-D-I-F-E-H-I-S-Q-Q-A-W-A-D-W-Q-K-H-Q-T-M-L-I-N-E-K-R-L-N-M-M-N-A-E-D-R-K-Y-L-Q-G-E-M-D-K-F-F-A-G-E-D-Y-A-Q-A-E-G-Y-V-P-P-A-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-K-K-D-A-E-G-Q-D-F-Q-L-Y-P-G-E-I-G-K-R-I-Y-N-E-I-S-K-E-A-W-S-Q-W-I-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-I-E-D-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-Q-D-V-H-I-A-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-L-N-I-S-T-A-L-R-S-F-T-Q-R-Y-I-D-L-W-Q-Q-Q-T-G-H-L-P-A-S-K-E-L-Y-G-V-P-S-P-C-I-V-E-T-G-E-D-Q-V-F-W-Q-P-Q-A-F-L-P-E-A-T-L-T-N-I-E-R-A-L-E-I-Q-L-H-P-D-I-H-D-F-Y-T-Q-Q-Y-A-G-D-M-M-A-D-L-G-N-H-R-F-T-L-L-Q-V-W-S-E-D-D-F-I-R-L-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-L-F-L-A-T-T-S-S-E-M-T-M-A-S-L-C-N-V-S-G-N-V-V-L-E-Q-F-G-S-D-K-R-T-L-L-A-S-T-L-S-H-F-L-D-A-L-R-P-V-L-P-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-N-P-L-V-Y-F-S-S-S-S-E-N-S-H-R-F-V-E-K-L-Q-L-P-A-I-R-I-P-I-A-G-A-R-E-K-L-R-V-E-Q-P-Y-I-L-L-V-P-S-Y-G-G-G-S-P-V-G-A-V-P-I-Q-V-I-R-F-L-N-D-V-H-N-R-S-L-I-R-G-V-I-A-A-G-N-T-N-F-G-D-A-Y-C-L-A-G-D-I-I-S-H-K-C-Q-V-P-Y-L-Y-R-F-E-L-L-G-T-A-E-D-V-A-N-V-R-K-G-V-T-E-F-W-Q-R-Q-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-P-L-S-P-G-S-R-I-L-I-G-L-I-R-G-Y-Q-L-V-I-S-P-L-L-G-P-R-C-R-F-H-P-T-C-S-H-Y-G-I-E-A-L-R-R-F-G-M-I-K-G-S-W-L-T-L-K-R-V-L-K-C-H-P-L-N-S-G-G-D-D-P-V-P-P-K-L-D-D-N-R-E-H"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-Q-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-S-V-S-K-E-A-W-Q-G-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-D-G-A-D-Q-A-S-G-Y-V-P-P-T-E-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-V-L-I-A-L-L-R-F-Y-K-V-A-V-S-P-M-L-G-N-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-V-R-R-V-C-R-C-H-P-F-S-A-G-G-V-D-L-V-P-P-P-N-S-D-T-R-A-R-G-E-A-D-A-R-S-H-R-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-K-K-E-A-E-G-L-G-F-Q-L-Y-P-G-P-L-G-K-R-I-F-D-N-V-S-K-E-A-W-G-L-W-Q-A-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-E-D-R-G-F-L-E-T-Q-M-V-N-F-L-F-E-G-K-D-V-E-I-E-G-Y-V-P-Q-K-D-D-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-K-T-Q-S-P-L-Q-W-L-A-T-T-L-I-R-G-Y-Q-V-F-I-S-P-F-L-G-A-N-K-C-R-F-H-P-T-C-S-T-Y-A-I-E-A-I-R-L-H-G-S-V-K-G-C-W-L-A-A-R-R-I-L-K-C-H-P-L-H-P-G-G-I-D-P-V-P-P-K-T-H-R-C-N-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-V-R-K-I-A-A-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-Y-K-D-I-A-H-P-I-N-T-E-T-R-E-K-I-Q-K-S-I-I-E-E-Y-E-R-A-K-M-E-E-E-S-S-E-K-V-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-L-L-I-C-I-I-K-M-Y-R-K-Y-I-S-P-L-K-R-P-S-C-R-F-Y-P-T-C-S-Q-Y-S-I-E-A-I-E-K-Y-G-A-L-K-G-T-L-I-S-I-K-R-I-L-K-C-H-P-F-N-E-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-E-I-V-E-M-S-L-L-L-D-F-Y-G-S-L-L-T-E-K-Q-N-K-I-M-D-L-Y-Y-N-N-D-Y-S-L-K-E-I-S-E-L-T-N-T-S-R-Q-A-V-H-D-I-V-K-R-C-H-K-A-L-I-Q-Y-E-E-R-L-H-M-M-E-R-F-I-N-L-E-N-S-K-E-K-L-L-N-M-L-N-K-V-T-K-E-N-I-K-E-I-D-H-I-K-K-Y-I-I-D-N-I"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-I-A-M-A-R-I-L-A-I-Y-R-V-L-L-D-G-S-I-S-S-D-E-A-I-Q-R-I-R-K-E-L-E-D-K-G-F-K-L-E-G-Y-D-E-N-P-I-G-F-G-I-V-A-L-N-L-K-I-T-A-P-E-E-D-G-I-T-D-A-I-S-S-V-L-E-E-L-E-G-V-S-S-V-E-L-D-M-V-S-R-V-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-L-I-M-L-I-R-F-Y-Q-R-Y-I-S-P-L-K-P-P-T-C-R-F-T-P-T-C-S-N-Y-F-I-Q-A-L-E-K-H-G-L-L-K-G-T-F-L-G-L-R-R-I-L-R-C-N-P-L-S-K-G-G-Y-D-P-V-P-E-E-F-S-F-K-P-R-R-R-W-S"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-T-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-H-L-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-Q-K-L-A-R-A-S-E-A-R-G-E-G-P-C-P-A-I-R-I-P-L-R-G-D-I-E-V-D-T-P-Y-V-L-I-V-P-T-Y-G-G-G-H-P-V-P-G-K-A-G-G-Y-V-P-K-Q-V-V-K-F-L-N-N-E-N-N-R-S-L-I-R-G-V-I-A-A-G-N-T-N-F-G-A-E-Y-C-Y-A-G-K-V-I-S-A-K-C-D-V-P-Y-L-Y-R-F-E-L-M-G-T-A-E-D-V-E-Q-V-L-D-G-L-D-E-F-W-K-D-T-P-W-R-Q-P-R-Q-L-Q-N-Q"} +{"text": "### FUNCTION Positive regulator of amyloid protein aggregation and proteotoxicity ### SEQUENCE -M-T-R-G-N-Q-R-E-L-A-R-Q-K-N-M-K-K-Q-S-D-S-V-K-G-K-R-R-D-D-G-L-S-A-A-A-R-K-Q-R-D-S-E-I-M-Q-Q-K-Q-K-K-A-N-E-K-K-E-E-P-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-K-I-R-K-I-N-G-E-S-R-L-R-G-V-A-S-I-A-F-D-D-C-F-V-V-N-D-I-R-I-I-E-G-E-K-G-I-F-I-A-M-P-S-R-K-T-T-K-G-T-F-R-D-I-A-H-P-V-N-T-E-T-R-Q-V-I-E-E-S-I-L-T-K-Y-Q-D-V-L-N-N-P-V-E-D-K-P-E-Q-E-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Y-P-L-L-A-L-I-K-L-Y-Q-W-T-I-S-P-L-L-G-P-V-C-R-Y-Y-P-S-C-S-H-Y-G-Y-T-S-I-D-R-H-G-A-I-K-G-T-A-L-T-A-W-R-I-L-R-C-N-P-W-S-P-G-G-V-D-H-V-P-P-R-K-R-P-R-W-H-E-L-L-R-N-A-L-R-G-E-K-G-G-E-S-A-A-D-V-P-S-G-G-S-V-S-E-P-P-G-P-A-A-E-T-S-P-N-A-Q-G-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-T-L-I-L-L-I-K-G-Y-R-R-L-I-S-P-L-F-P-P-S-C-R-F-Q-P-T-C-S-Q-Y-T-L-E-A-I-E-K-F-G-A-L-R-G-S-W-L-G-L-R-R-I-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P-P-V-T-K-K"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-A-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-S-L-I-L-W-S-I-K-G-Y-R-R-W-I-S-P-L-F-P-P-S-C-R-F-Q-P-T-C-S-Q-Y-A-L-E-A-V-E-R-F-G-V-L-R-G-S-W-L-A-L-K-R-L-G-R-C-H-P-F-H-P-G-G-Y-D-P-V-P-H-L-C-H-H-D-L-D-N-T-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-Q-C-I-K-L-N-K-E-A-E-G-M-D-F-A-P-L-P-G-E-L-G-K-R-I-W-N-Q-V-S-K-E-A-W-A-G-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-L-K-Q-V-E-K-H-F-F-E-G-G-A-D-T-A-Q-G-Y-V-P-P-P-A-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-Q-C-V-L-L-K-K-E-A-D-G-L-D-F-S-P-Y-P-G-E-L-G-K-R-I-Y-E-Q-V-S-K-E-A-W-Q-Q-W-L-K-H-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-Q-Y-L-A-R-Q-M-E-R-Y-F-F-G-E-G-A-D-Q-P-T-G-Y-V-P-P-T-A"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-N-V-T-D-V-K-I-R-R-V-V-A-E-G-R-M-K-A-L-A-S-I-T-L-D-H-E-F-V-V-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-Q-E-G-I-F-R-D-V-A-H-P-I-N-A-L-M-R-K-K-V-E-D-S-V-L-E-A-Y-A-I-R-E-E-N-G-E-A-S-E-L-E-L-A-A-L-E-A-T-D-P-S"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-T-L-D-K-T-N-R-M-N-Y-L-I-D-F-Y-Q-E-L-L-T-P-K-Q-R-N-Y-M-S-L-Y-Y-L-D-D-F-S-L-G-E-I-A-D-E-F-E-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-Q-Y-E-E-R-L-G-L-F-A-K-Y-E-Q-R-K-L-L-L-D-Q-L-K-Q-L-D-L-P-S-E-A-H-V-T-I-A-A-L-E-Q-L-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-V-L-L-G-G-I-H-F-Y-Q-K-V-I-S-P-M-K-P-A-T-C-R-F-Y-P-T-C-S-H-Y-G-K-E-A-I-E-K-H-G-A-L-R-G-G-Y-L-T-T-R-R-L-L-R-C-Q-P-F-H-P-G-G-L-D-F-V-P-E-T-F-D-W-K-A-P-L-Q-R-E-N-P-A-E-H-Q-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-E-T-V-L-I-A-L-L-R-F-Y-K-V-A-V-S-P-M-L-G-N-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-V-R-R-V-C-R-C-H-P-F-S-A-G-G-I-D-L-V-P-P-P-N-S-D-T-R-A-R-G-E-A-D-A-R-S-H-R-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-Q-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-S-V-S-K-E-A-W-Q-G-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-D-G-A-D-Q-A-S-G-F-V-P-P-T-E-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-P-R-T-V-F-C-Q-Y-E-Q-R-D-A-E-G-L-D-F-V-P-Y-P-G-E-L-G-Q-R-I-F-N-N-I-G-K-Q-A-W-A-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-T-P-E-H-R-A-F-L-E-G-E-L-V-K-F-L-F-E-K-D-A-Q-K-P-A-G-F-T-P-E-A"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-N-Y-R-I-N-S-L-F-E-F-Y-Q-P-L-L-T-K-K-Q-N-D-Y-L-E-L-Y-Y-G-D-D-Y-S-L-G-E-I-A-E-N-F-H-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-S-I-L-E-D-Y-E-A-K-L-H-L-Y-A-E-F-Q-V-R-N-Q-Q-A-D-R-I-Q-R-Y-V-R-E-N-Y-P-D-D-A-T-L-N-H-L-V-N-H-L-E-S-L-E-E-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-R-L-V-K-A-L-V-I-A-Y-Q-R-F-F-S-A-R-R-P-Y-R-V-C-R-F-E-P-T-C-S-E-Y-M-L-Q-A-I-D-R-Y-H-S-R-G-I-L-M-G-L-A-R-I-L-R-C-Q-P-F-A-R-G-G-Y-D-P-L-P-D-H-F-T-L-K-R-N-Q-P-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-L-E-K-N-E-R-I-N-A-L-F-A-F-Y-Q-P-L-L-T-A-K-Q-N-D-Y-L-Q-L-Y-Y-A-D-D-Y-S-L-G-E-I-A-T-E-F-S-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-G-Y-E-Q-K-L-H-L-Y-A-E-F-E-A-R-N-Q-Q-A-D-R-I-R-D-Y-V-L-S-H-Y-P-T-D-Q-T-L-R-D-L-I-D-G-M-E-N-L-E-A-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-R-I-L-R-W-F-I-R-L-Y-Q-I-A-I-S-P-L-L-G-P-R-C-R-Y-I-P-T-C-S-Q-Y-A-L-E-A-L-Q-T-H-G-A-I-K-G-V-W-L-S-S-K-R-I-C-R-C-H-P-W-G-G-S-G-Y-D-P-V-P-P-K-A-I-R-F-I-S-F-H-Q-I-D-S-Q-T-H-H-V-A-V-P-F-R-D-R-L-M-K-Q-N-L-S-N-H-L-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-Q-V-F-C-R-K-Y-Q-K-E-M-E-G-L-D-F-A-P-F-P-G-A-K-G-Q-E-F-F-E-N-V-S-K-Q-A-W-Q-E-W-L-Q-H-Q-T-T-L-I-N-E-K-R-L-N-V-F-E-P-E-A-K-K-F-L-E-E-Q-R-E-K-F-F-N-N-D-E-S-V-E-K-A-E-G-W-K-P-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-Q-R-I-I-F-C-E-Y-E-K-R-D-T-E-G-L-D-F-V-P-Y-P-G-E-L-G-Q-K-I-F-A-C-I-G-K-V-G-W-A-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-N-P-S-H-R-A-F-L-E-E-E-L-N-K-F-L-F-E-R-S-A-A-K-P-E-G-Y-I-E-P-D-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-R-F-V-R-S-L-S-S-T-G-R-S-Q-T-G-S-L-P-V-R-G-L-R-K-L-L-R-F-Y-Q-L-T-F-S-S-L-V-G-T-Q-C-R-H-L-P-T-C-S-A-Y-M-D-E-A-L-A-R-H-G-V-W-A-G-L-F-I-G-L-A-R-L-S-R-C-H-P-W-G-T-A-G-Y-D-P-V-P-D-Q-L-D-A-N-V-P-R-L-Q-P-W-R-H-G-R-W-R-G-P-L-E-I-T-W-K-P-E-H-K-D-Q-N-L"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-T-A-Q-V-D-R-Y-V-S-F-K-G-I-D-W-V-G-R-S-R-E-I-F-A-R-L-Q-S-H-I-D-Q-A-N-S-P-F-W-P-Y-F-T-R-Q-R-K-L-A-H-S-Q-G-L-D-D-L-R-V-L-H-N-Y-L-P-T-L-R-E-L-L-E-N-M-G-D-L-K-T-L-G-M-L-E-E-L-E-Q-I-C-M"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-Q-I-L-E-R-Y-P-K-D-N-F-L-Q-E-Q-I-E-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-L-V-R-F-Y-Q-R-F-I-S-P-V-F-P-P-S-C-R-F-E-L-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-F-K-G-V-L-M-G-L-A-R-I-L-R-C-H-P-W-S-K-T-G-K-D-P-I-P-D-H-F-S-L-K-R-N-Q-E-G-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-L-L-F-I-W-L-I-R-G-Y-R-M-F-I-S-P-L-F-L-P-T-C-R-F-Q-P-T-C-S-M-Y-A-I-E-A-I-E-R-F-G-V-L-R-G-S-W-M-A-T-R-R-I-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P-E-V-V-E-K-V-K-E-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-M-V-Q-C-T-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-S-I-S-K-E-A-W-Q-Q-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-F-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-A-Q-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-V-L-F-A-L-L-R-F-Y-K-I-A-V-S-P-M-L-G-N-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-A-R-R-L-C-R-C-H-P-F-S-A-G-G-I-D-L-V-P-P-P-T-P-K-K-R"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-L-N-I-S-T-A-L-R-S-F-T-Q-R-Y-I-D-L-W-Q-Q-Q-T-G-H-L-P-A-S-K-E-L-Y-G-V-P-S-P-C-I-V-E-T-G-E-D-Q-V-F-W-Q-P-Q-A-F-L-P-E-A-T-L-T-N-I-E-R-A-L-E-I-Q-L-H-P-D-I-H-D-F-Y-T-Q-Q-Y-A-G-D-M-M-A-D-L-G-N-H-R-F-T-L-L-Q-V-W-S-E-D-D-F-I-R-L-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-L-F-L-A-T-T-S-S-E-M-T-M-A-S-L-C-N-V-S-G-N-V-V-L-E-Q-F-G-S-D-K-R-T-L-L-A-S-T-L-S-H-F-L-D-A-L-R-P-V-L-P-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-K-K-D-A-E-G-Q-D-F-Q-L-Y-P-G-E-I-G-K-R-I-Y-N-E-I-S-K-E-A-W-S-Q-W-I-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-I-E-D-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-Q-D-V-H-I-A-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-P-L-S-P-G-S-R-I-L-I-G-L-I-R-G-Y-Q-L-V-I-S-P-L-L-G-P-R-C-R-F-H-P-T-C-S-H-Y-G-I-E-A-L-R-R-F-G-M-I-K-G-S-W-L-T-L-K-R-V-L-K-C-H-P-L-N-S-G-G-D-D-P-V-P-P-K-L-D-D-N-R-E-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-N-P-L-V-Y-F-S-S-S-S-E-N-S-H-R-F-V-E-K-L-Q-L-P-A-I-R-I-P-I-A-G-A-R-E-K-L-R-V-E-Q-P-Y-I-L-L-V-P-S-Y-G-G-G-S-P-V-G-A-V-P-I-Q-V-I-R-F-L-N-D-V-H-N-R-S-L-I-R-G-V-I-A-A-G-N-T-N-F-G-D-A-Y-C-L-A-G-D-I-I-S-H-K-C-Q-V-P-Y-L-Y-R-F-E-L-L-G-T-A-E-D-V-A-N-V-R-K-G-V-T-E-F-W-Q-R-Q-N"} +{"text": "### FUNCTION Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis Negative regulator of Toll-like receptor and T-cell receptor function Prevents hyperresponsiveness of the immune system and maintains immune homeostasis Inhibits JUN/AP1 and NF-kappa-B activation Promotes Fas-induced apoptosis ### SEQUENCE -M-E-P-F-S-S-K-S-L-A-L-Q-A-E-K-K-L-L-S-K-M-A-G-R-S-V-A-H-L-F-I-D-E-T-S-S-A-V-L-D-E-L-Y-R-V-S-K-E-Y-T-H-S-R-P-Q-A-Q-R-V-I-K-D-L-I-K-V-A-V-K-V-A-V-L-H-R-S-G-C-F-G-P-S-E-L-A-L-A-A-R-F-R-Q-K-L-Q-Q-G-A-M-T-A-L-S-F-G-E-V-D-F-T-F-E-A-A-V-L-A-G-L-L-T-E-C-R-D-M-L-L-E-L-V-E-H-H-L-T-P-K-S-H-N-R-I-R-H-V-F-D-H-F-S-D-P-G-L-L-T-A-L-Y-G-P-D-F-T-Q-H-L-G-K-I-C-D-G-L-R-K-M-L-D-E-G-K-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-L-I-K-A-F-L-V-Q-L-L-L-L-P-I-F-F-Y-K-R-F-I-S-P-L-T-P-P-S-C-R-F-T-P-S-C-S-S-Y-A-I-E-A-L-R-K-Y-G-P-G-K-G-L-L-L-S-I-K-R-I-L-R-C-H-P-W-G-G-S-G-Y-D-P-V-P"} +{"text": "### FUNCTION May promote cell proliferation and inhibition of apoptosis of preadipocytes ### SEQUENCE -M-T-A-A-S-R-Q-E-V-L-G-L-Y-R-S-F-F-R-L-A-R-K-W-Q-A-A-S-G-Q-M-E-D-T-I-K-E-K-Q-Y-I-L-N-E-A-R-T-L-F-Q-K-N-K-N-L-T-D-P-D-L-I-K-Q-C-I-D-E-C-T-A-R-I-E-I-G-L-H-Y-Q-I-P-Y-P-R-P-I-H-L-P-P-M-G-L-T-P-R-R-G-R-G-L-Q-T-Q-E-K-L-R-K-F-S-K-P-L-Y-L-K-S-H-D-E-V-S"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-N-I-T-D-V-R-I-R-R-V-D-N-K-N-P-G-S-K-L-L-A-Y-V-T-V-T-F-D-D-C-L-V-L-H-N-I-R-V-I-R-G-Q-K-G-V-F-I-V-M-P-N-R-R-T-K-V-G-E-Y-K-D-I-V-H-P-I-N-Q-S-F-R-E-I-L-Q-S-A-I-F-K-E-Y-V-K-E-N-P-S-S-L-E-L-E-I-G"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-L-I-V-Y-F-S-S-R-S-G-N-T-H-R-F-V-E-R-L-G-V-R-S-S-R-I-P-L-E-A-S-G-A-L-Q-V-R-E-P-F-V-L-V-T-P-T-Y-G-G-G-S-T-K-G-A-V-P-N-P-V-I-R-F-L-N-D-A-D-N-R-A-L-I-R-G-V-I-A-A-G-N-S-N-F-G-E-A-F-C-I-A-G-N-I-I-S-A-K-C-G-V-P-Y-L-Y-R-F-E-L-L-G-T-A-E-D-V-G-N-V-R-N-G-M-E-Q-F-W-T-R-Q-T-Q-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-K-V-F-C-K-K-Y-H-Q-E-L-D-A-I-P-F-Q-P-L-P-G-E-L-G-K-K-I-H-N-E-I-S-N-K-A-W-Q-A-W-L-A-H-Q-T-I-L-I-N-E-Y-R-L-N-L-I-E-T-K-A-K-E-F-L-K-E-E-M-H-K-F-L-F-E-G-K-E-E-K-P-E-Q-F-S-E-I"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-F-F-K-K-I-T-L-I-P-F-V-M-L-I-N-L-Y-R-Y-C-I-S-P-F-I-P-A-R-C-R-Y-Y-P-T-C-S-E-Y-A-L-E-A-L-K-T-H-G-I-L-K-G-L-Y-L-T-T-R-R-L-L-R-C-H-P-L-S-K-R-D-Y-Y-D-L-V-P-C-K-N-K-K-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-M-V-Q-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-G-I-S-K-E-A-W-Q-A-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-F-F-F-G-E-G-A-D-T-A-Q-G-Y-V-P-P-S-A-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-V-L-I-A-L-L-R-F-Y-K-V-A-V-S-P-M-L-G-N-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-A-R-R-I-C-R-C-H-P-F-S-A-G-G-I-D-L-V-P-P-P-T-S-E-K-R"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-I-R-K-I-S-S-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-T-G-E-F-K-D-I-A-H-P-I-V-M-D-S-R-E-K-I-Q-N-E-I-L-S-A-Y-A-K-A-I-E-E-Q-D-V-E-E-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-D-R-V-E-I-S-M-L-M-D-F-Y-S-S-L-L-T-E-K-Q-R-S-V-M-A-L-Y-Y-D-D-D-L-S-L-A-E-I-A-E-L-N-K-T-S-R-Q-A-I-H-D-L-I-K-R-C-D-K-Q-L-L-S-Y-E-S-K-L-N-L-L-Q-K-S-M-R-K-E-K-Y-I-M-N-F-L-E-E-L-K-E-K-Y-S-V-S-D-K-D-Y-L-M-F-K-E-K-L-E-N-L"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-S-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-H-C-V-K-L-N-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-K-L-W-Q-S-V-S-K-E-A-W-A-G-W-L-K-H-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-S-R-A-R-Q-Y-L-L-K-Q-T-E-K-Y-F-F-G-D-G-A-D-E-A-A-G-Y-V-P-P-P-S-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-N-N-K-T-P-F-L-S-A-I-F-T-A-L-I-R-G-Y-Q-R-F-F-S-A-F-T-F-S-S-C-R-F-Y-P-T-C-S-N-Y-A-L-W-L-L-Y-F-E-N-P-L-S-A-M-G-K-I-A-I-R-I-L-S-C-N-P-F-C-S-G-G-I-A-Y-P-T-T-R-L-K-R-P-S-L-L-Q-S-H-K-D-F-N-R-N-F-K-T-I-T-F-W-L-V-P-T-T-K-S-H-A-T-Y-Y-I-I-K-V"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-I-R-K-I-S-S-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-T-G-E-F-K-D-I-A-H-P-I-V-M-D-S-R-E-K-I-Q-N-E-I-L-S-A-Y-A-K-A-I-E-E-Q-D-V-E-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-D-R-V-E-I-S-M-L-M-D-L-Y-S-S-L-L-T-E-K-Q-R-S-V-M-A-L-Y-Y-D-D-D-L-S-L-A-E-I-A-E-L-N-K-T-S-R-Q-A-I-H-D-L-I-K-R-C-D-K-Q-L-L-S-Y-E-S-K-L-N-L-L-Q-K-S-M-R-K-E-K-Y-I-M-N-F-L-E-E-L-K-E-K-Y-S-V-S-D-K-D-Y-L-M-F-K-E-K-L-E-N-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-Q-R-D-A-E-G-Q-D-F-Q-L-Y-P-G-D-T-G-K-R-I-F-N-E-I-S-K-E-A-W-S-K-W-M-A-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-P-D-D-R-K-L-L-E-Q-E-M-I-K-F-L-F-E-G-H-E-V-H-I-E-G-Y-T-P-P-E-E"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-I-D-E-T-S-Q-A-L-R-D-F-S-Q-R-Y-C-D-L-W-Q-Q-K-S-G-H-A-P-A-S-Q-E-L-Y-G-I-P-S-P-C-V-M-A-T-D-E-D-E-V-W-W-Q-P-R-P-F-T-L-A-P-N-L-D-A-V-E-R-A-L-D-I-R-L-Q-P-A-V-T-A-F-Y-T-S-Q-F-A-G-D-M-T-G-T-L-D-G-R-P-L-S-L-V-Q-V-W-S-E-D-D-F-I-R-V-Q-E-N-L-I-G-H-L-V-M-K-R-R-L-K-Q-S-P-T-L-F-I-A-T-T-D-S-E-L-E-V-I-S-V-C-N-V-S-G-E-V-I-L-E-Q-L-G-T-K-K-R-Q-V-I-A-S-S-I-E-N-L-L-I-A-L-Q-P-L-I-I-N-C-S-N"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-T-N-P-T-I-L-L-T-T-V-L-L-T-L-L-T-T-P-A-L-A-Q-F-G-F-F-D-Q-M-F-G-G-G-G-G-Q-Q-Q-G-H-H-H-H-H-E-Q-E-A-Q-N-V-R-S-D-A-S-W-Y-Q-S-Q-Y-E-G-A-Q-C-T-H-Y-L-C-P-G-T-L-S-C-V-H-F-P-H-H-C-P-C-S-W-E-T-V-E-D-K-V-E-L-G-E-G-I-A-V-C-G-S-K-G-G-W-V-E-G-E-F-G-K-K-V-E-M-A-R-K-G-L-L"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -S-P-A-L-D-D-E-R-N-D-N-F-I-R-L"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -P-A-P-D-S-S-F-L-R-D-P"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -S-D-Y-L-Q-L-A-R-G"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -P-A-P-D-S-S-F-I-R-D-P"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -P-A-P-E-S-G-F-I-R-D-P"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -S-P-T-L-D-D-E-H-N-D-N-F-V-R-L"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -P-A-P-D-S-S-F-L-R-D-P"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -P-D-Y-L-Q-L-A-R-A"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -P-A-P-E-T-N-Y-L-R-D-P"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -A-D-Y-L-Q-L-T-R-A"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -A-D-Y-L-R-L-A-R-A"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -P-A-S-D-S-G-F-L-R-D-P"} +{"text": "### FUNCTION FMRFamides and FMRFamide-like peptides are neuropeptides ### SEQUENCE -S-D-Y-L-Q-L-A-R-T"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-V-V-F-F-L-L-D-F-Y-R-Y-G-L-S-S-F-R-Q-T-L-G-M-Y-G-V-C-R-Y-Y-P-T-C-S-Q-Y-C-R-E-A-V-Q-K-H-G-I-I-H-G-L-Y-L-C-L-R-R-L-M-R-C-H-P-W-G-A-A-G-W-D-P-V-P-E-K-S-N-L-G-I-K-R-T-K-K-A-D-H-P-L-K-K-K-V-S-L-M-R-V-M-H-L-F-F-K"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-S-K-P-D-R-Y-V-S-F-V-G-I-D-G-D-S-N-A-R-K-L-V-A-L-L-R-R-H-I-D-D-P-A-R-T-N-R-F-W-E-L-F-K-D-K-L-E-K-I-N-K-P-D-E-T-S-G-F-S-Q-D-E-L-Y-L-V-H-A-Y-I-N-N-I-R-E-L-F-E-T-Y-D-D-Q-P-A-L-A-L-L-D-R-I-E-A-E-S-C"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-W-L-L-K-R-I-V-I-F-P-I-W-V-Y-Q-V-A-L-A-P-Y-L-T-P-C-C-R-F-Q-P-T-C-S-A-Y-A-H-E-A-I-N-K-H-G-I-V-K-G-I-W-L-A-G-K-R-I-L-R-C-H-P-C-G-K-S-G-Y-D-P-V-Q"} +{"text": "### FUNCTION May have antimicrobial activity ### SEQUENCE -V-L-S-H-N-N-E-S-S-Y-S-D-T-S-S-C-T-S-Q"} +{"text": "### FUNCTION May have antimicrobial activity ### SEQUENCE -D-L-P-E-C-C-S-A-T-E-L-E-L-D-S-G-K-Q-T-S"} +{"text": "### FUNCTION May have antimicrobial activity ### SEQUENCE -S-E-S-I-L-I-V-H-Q-Q-Q-S-R-S-S-G-S"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -A-I-T-X-G-Q-V-T-S-K-L-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-E-Y-L-K-Q-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-S-I-S-K-Q-A-W-S-E-W-I-K-K-Q-T-M-L-V-N-E-K-K-L-S-M-M-N-A-E-H-R-K-L-L-E-T-E-M-V-N-F-L-F-E-G-K-E-V-Q-I-E-G-Y-V-P-V-E-Q-K"} +{"text": "### FUNCTION Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors ### SEQUENCE -M-V-S-V-V-G-E-M-F-C-N-P-Y-T-T-E-L-V-V-R-R-R-R-E-S-L-K-R-E-R-Y-D-V-F-D-L-S-N-N-L-I-F-T-V-D-G-G-I-W-N-I-R-R-K-R-V-L-R-D-A-A-G-I-P-L-L-S-M-R-T-K-G-L-V-P-M-R-Y-N-W-E-V-Y-K-G-D-S-T-E-S-D-N-L-L-F-S-A-R-E-P-N-L-L-S-F-K-T-S-L-D-V-T-L-P-P-D-Q-S-S-T-D-I-S-S-V-E-P-D-F-Q-T-F-G-R-Y-I-G-S-S-F-K-L-F-E-P-I-H-N-T-L-L-A-E-V-V-H-D-F-T-W-G-G-L-I-K-G-S-Y-S-F-K-V-R-V-N-P-Y-V-D-F-A-F-V-V-A-L-L-V-I-T-D-D-T-S-N-L-R"} +{"text": "### FUNCTION Critical role in copper ### SEQUENCE -M-T-V-K-I-C-D-C-E-G-E-C-C-K-D-S-C-H-C-G-S-T-C-L-P-S-C-S-G-G-E-K-C-K-C-D-H-S-T-G-S-P-Q-C-K-S-C-G-E-K-C-K-C-E-T-T-C-T-C-E-K-S-K-C-N-C-E-K-C"} +{"text": "### FUNCTION Stationary phase-essential protein not required for growth on nonfermentable carbon sources ### SEQUENCE -M-G-S-F-W-D-A-F-A-V-Y-D-K-K-K-H-A-D-P-S-V-Y-G-G-N-H-N-N-T-G-D-S-K-T-Q-V-M-F-S-K-E-Y-R-Q-P-R-T-H-Q-Q-E-N-L-Q-S-M-R-R-S-S-I-G-S-Q-D-S-S-D-V-E-D-V-K-E-G-R-L-P-A-E-V-E-I-P-K-N-V-D-I-S-N-M-S-Q-G-E-F-L-R-L-Y-E-S-L-R-R-G-E-P-D-N-K-V-N-R"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-S-Q-S-R-W-S-I-V-L-I-F-A-L-F-I-F-G-S-T-G-V-N-A-F-F-N-F-G-H-H-Q-Q-Q-Q-Q-Q-Q-Q-Q-S-Y-E-D-Q-V-L-N-N-P-C-D-G-Y-L-C-P-D-T-L-T-C-V-A-Q-Q-K-D-C-P-C-P-F-P-K-S-Q-L-K-C-V-L-P-D-N-K-F-V-C-I-S-K-P-A-T-H-N-E-K-F-R-A-I-Y-D-D-P-V-K-G-P-K-A-K-N-K-G-F-R-D-C-G-W-V-S-D-A-Y-K-N-H"} +{"text": "### FUNCTION Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions ### SEQUENCE -M-T-K-K-D-K-K-A-K-G-P-K-M-S-T-I-T-T-K-S-G-E-S-L-K-V-F-E-D-L-H-D-F-E-T-Y-L-K-G-E-T-E-D-Q-E-F-D-H-V-H-C-Q-L-K-Y-Y-P-P-F-V-L-H-D-A-H-D-D-P-E-K-I-K-E-T-A-N-S-H-S-K-K-F-V-R-H-L-H-Q-H-V-E-K-H-L-L-K-D-I-K-T-A-I-N-K-P-E-L-K-F-H-D-K-K-K-Q-E-S-F-D-R-I-V-W-N-Y-G-E-E-T-E-L-N-A-K-K-F-K-V-S-V-E-V-V-C-K-H-D-G-A-M-V-D-V-D-Y-R-T-E-P-L-Q-P-L-I"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-W-A-G-V-K-L-L-H-G-Y-R-Y-L-L-S-P-W-I-G-N-Q-C-R-F-Y-P-S-C-S-H-Y-A-E-E-A-L-K-T-H-G-F-L-A-G-I-Y-L-T-A-R-R-L-I-K-C-H-P-W-H-P-G-G-I-D-P-V-P-E-H-E-A-T-C-C-S-H-T-H-P-T-H-G-K-H"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-F-C-R-K-Y-K-Q-Q-L-E-G-L-D-F-P-P-Y-P-G-A-K-G-Q-D-L-F-D-N-V-S-K-K-A-W-Q-E-W-M-A-H-Q-T-M-L-I-N-E-K-R-L-N-V-M-D-M-G-T-K-V-Y-L-T-E-Q-M-H-K-F-L-S-G-E-G-Y-D-Q-A-D-G-Y-V-P-P-S-N-Q"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-G-L-I-V-Y-Y-S-S-R-S-E-N-T-H-R-F-V-A-R-L-G-L-R-A-A-R-I-P-A-S-G-A-D-A-F-H-I-R-E-P-F-V-L-V-V-P-T-Y-S-S-G-D-G-K-G-A-V-P-K-Q-V-I-R-C-L-N-D-A-E-N-R-K-H-I-R-G-V-I-A-A-G-N-S-N-F-G-E-T-Y-G-L-A-G-D-V-I-S-R-K-C-Q-V-P-Y-L-Y-R-F-E-L-M-G-T-E-E-D-V-A-N-V-K-H-G-M-E-R-F-W-T-R-E-Q-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-L-P-S-R-G-T-D-W-I-A-P-V-L-R-L-P-R-N-A-G-R-G-L-I-W-L-Y-R-H-T-L-S-P-L-V-G-Y-N-C-R-H-Y-P-T-C-S-M-Y-G-D-E-A-I-R-K-F-G-L-W-A-G-G-W-M-T-L-A-R-L-L-R-C-Q-P-W-G-T-S-G-I-D-L-V-P-Q-T-A-P-S-R-A-R-W-Y-L-P-W-R-Y-A-R-W-R-G-V-N-A-P-P-P-D-V-A-E-P-C-G-C-G-S-H-S-Q-L-T-P-H"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-S-A-S-F-D-R-Y-V-S-F-Q-H-C-D-W-E-G-R-S-E-R-V-M-Q-R-L-Q-R-H-V-E-A-A-E-N-P-F-W-A-Y-F-A-Q-K-R-A-E-L-R-D-K-Q-G-L-D-D-L-R-I-L-H-N-Y-L-P-T-L-R-E-L-L-E-D-N-G-D-L-E-T-L-E-M-L-E-D-L-E-A-N-L-M"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-H-C-I-K-L-N-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-K-I-W-Q-S-V-S-K-E-A-W-A-G-W-L-K-H-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-A-R-A-R-Q-Y-L-L-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-Q-G-Y-V-P-P-Q-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-L-A-L-L-R-V-Y-K-I-A-L-S-P-Y-L-G-S-Q-C-R-F-L-P-T-C-S-D-Y-A-R-D-A-I-V-H-H-G-A-A-R-G-S-W-M-A-A-C-R-L-C-R-C-H-P-F-A-Q-G-G-Y-D-P-V-P-G-T-E-A-D-T-P-V-H-A-A-T-G-H-A-P-V-A-I-R-L-P-R-P"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-E-K-K-E-L-Y-D-G-F-L-T-L-E-K-H-A-Q-Q-M-L-R-E-I-A-A-M-K-D-D-M-A-E-T-L-E-R-N-A-E-L-E-I-E-N-K-H-L-R-Q-H-L-A-E-L-E-K-D-D-N-K-T-S-D-G-G-V-E-L-S-K-S-K-Q-N-L-E-S-L-Y-N-E-G-F-H-V-C-P-M-F-Y-G-Q-R-R-V-N-D-E-P-C-A-F-C-T-E-I-I-Y-G-E-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-V-L-T-W-L-V-R-G-Y-Q-R-F-I-S-P-L-L-P-P-S-C-R-Y-Y-P-T-C-S-T-Y-M-I-Q-A-L-Q-K-H-G-A-I-K-G-S-L-M-G-I-A-R-I-L-R-C-N-P-F-V-K-G-G-L-D-P-V-P-A-F-F-T-L-R-R-N-P-H-P-E-N-D-L-D-L-S-D-I-Q-N-L-N-H-K-L-G-G-R-H-G"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-N-Y-R-M-N-S-L-F-E-F-Y-G-P-L-L-T-D-K-Q-H-A-Y-L-A-L-Y-Y-G-D-D-Y-S-L-G-E-I-A-T-E-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-E-A-S-L-E-E-Y-E-K-K-L-H-L-F-A-N-Y-Q-A-Q-N-E-A-V-D-T-L-V-S-Y-A-R-T-H-Y-P-D-D-K-A-L-S-T-L-L-E-R-V-A-D-Q-T-A-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-V-L-I-A-L-L-R-F-Y-K-V-A-V-S-P-M-L-G-N-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-V-R-R-V-C-R-C-H-P-F-S-A-G-G-I-D-L-V-P-P-P-N-S-D-T-R-A-R-G-E-A-D-A-R-S-H-R-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-Q-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-S-V-S-K-E-A-W-Q-G-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-D-G-A-D-Q-A-S-G-Y-V-P-P-T-E-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-N-E-I-S-K-E-A-W-G-Q-W-M-A-K-Q-T-M-L-I-N-E-K-K-L-N-T-M-N-P-D-D-R-K-L-L-E-Q-E-M-V-R-F-L-F-E-G-H-D-V-H-I-D-G-Y-T-P-P-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-S-L-S-L-G-S-K-I-L-I-L-L-I-R-G-Y-Q-L-G-I-S-P-L-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-G-I-E-A-L-R-R-F-G-M-I-K-G-S-W-L-T-V-K-R-I-L-K-C-H-P-L-H-E-G-G-D-D-P-V-P-P-R-K-N-D-D-N-R-E-N"} +{"text": "### FUNCTION Post-meiotically transcribed gene that has a role in late spermiogenesis ### SEQUENCE -M-E-Q-G-V-I-E-E-L-I-H-L-Q-L-P-E-M-E-V-A-N-V-V-N-V-R-D-G-N-G-N-G-N-D-I-D-G-G-N-E-V-W-A-Q-H-Q-L-D-N-V-N-N-R-Q-M-A-I-L-L-D-A-P-P-E-P-P-I-V-L-H-Q-L-P-Q-P-V-N-V-P-Q-R-L-R-K-K-R-C-F-W-T-I-T-K-H-F-H-A-Q-P-E-R-C-A-L-L-S-N-A-W-Q-A-V-Q-Y-V-Q-P-A-Q-R-S-E-H-F-A-N-Y-M-Y-K-H-M-N-S-R-N-Y-P-N-G-E-G-L-P-N-R-W-G-H-F"} +{"text": "### FUNCTION Post-meiotically transcribed gene that has a role in late spermiogenesis ### SEQUENCE -M-E-N-R-V-A-D-E-L-I-H-L-P-L-P-E-V-Q-A-V-N-V-I-N-V-R-H-G-D-G-D-G-D-G-E-N-G-W-E-R-H-L-D-D-E-Q-M-Q-A-M-R-L-E-N-P-Q-V-A-M-L-L-D-A-P-H-E-P-P-I-E-L-H-H-M-L-E-P-V-N-V-P-E-R-P-R-K-K-R-S-F-L-T-I-S-K-P-F-H-V-Q-P-E-R-C-A-L-I-S-N-G-W-R-A-V-Q-C-V-Q-P-E-K-R-G-E-C-F-A-N-Y-L-I-K-H-M-N-S-R-N-Y-P-N-G-E-G-L-P-K-R-W-G-Q-Y"} +{"text": "### FUNCTION Post-meiotically transcribed gene that has a role in late spermiogenesis ### SEQUENCE -M-E-Q-G-V-V-E-E-L-I-H-L-Q-L-P-E-V-E-A-V-D-V-V-N-V-P-D-G-N-G-D-G-D-G-D-G-D-G-D-G-N-D-A-W-E-R-Q-L-D-E-V-Q-M-Q-A-M-R-L-E-N-P-Q-V-A-M-L-L-D-A-P-H-E-P-P-I-E-L-H-H-M-L-E-P-V-N-V-P-Q-R-P-R-K-K-R-S-F-L-T-I-S-K-P-F-H-V-Q-P-E-R-C-A-L-I-S-N-G-W-R-A-V-Q-C-V-Q-P-E-K-R-G-E-Y-F-A-N-Y-L-I-K-H-M-N-S-R-N-Y-P-N-G-E-G-L-P-N-R-W-G-Q-F"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-L-Y-E-S-C-V-R-G-A-L-R-A-Y-K-L-T-L-S-P-L-I-G-R-Q-C-R-F-F-P-T-C-S-E-Y-A-A-E-A-L-I-G-H-G-P-V-R-G-S-W-L-T-V-R-R-L-C-R-C-H-P-W-G-P-S-G-W-D-P-P-P-P-P-R-R-K-G-A-K-W-T-C-E-T"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-F-L-L-S-K-L-L-L-G-L-I-R-F-Y-Q-Y-C-I-S-P-L-I-P-P-R-C-R-Y-T-P-T-C-S-Q-Y-A-V-E-A-V-K-K-Y-G-A-F-K-G-L-R-L-A-I-K-R-I-A-R-C-H-P-F-G-G-H-G-H-D-P-V-P"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-A-L-T-I-S-A-Q-L-D-K-F-V-S-S-Y-V-E-H-A-K-G-E-G-L-K-I-A-F-D-S-E-W-P-S-P-C-Y-E-E-T-A-K-D-G-E-L-V-E-W-A-P-K-R-Q-S-P-P-L-S-F-N-N-V-E-D-A-L-S-L-K-L-H-A-D-Y-C-C-Y-F-T-T-Y-Y-S-D-N-L-K-A-K-A-P-Q-G-D-C-E-L-L-Q-V-F-N-R-E-D-F-E-R-L-Q-Q-N-L-I-G-H-L-L-M-K-Q-R-L-N-Q-A-P-T-L-F-F-G-L-T-D-E-E-D-F-I-L-T-V-I-N-E-T-G-E-V-A-L-E-Q-V-G-Q-A-P-T-Q-I-L-A-N-S-L-A-E-F-I-E-Q-L-S-P-L-N-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-R-K-L-Q-K-E-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-E-W-Q-K-K-Q-T-M-L-I-N-E-H-K-L-N-M-M-E-P-N-A-R-A-F-L-E-E-K-M-S-A-Y-L-F-D-D-V-E-P-T-I-E-G-Y-V-P-P-E-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-Q-Y-E-Q-R-D-A-E-G-L-D-F-V-P-Y-P-G-E-L-G-Q-R-I-F-N-N-I-G-K-Q-A-W-A-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-T-P-E-H-R-A-F-L-E-G-E-L-V-K-F-L-F-E-K-D-A-E-K-P-A-G-F-T-P-E-A"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-R-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-K-G-V-N-E-F-W-Q-Q-L-P-R-S-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-K-G-V-N-E-F-W-Q-Q-L-S-R-S-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-K-G-V-N-E-F-W-Q-Q-L-S-R-S-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-K-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-A-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-E-I-F-D-D-I-L-A-K-Y-P-S-D-H-Y-L-R-D-K-I-S-I-L-T-S-I-D-N-R-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-D-I-E-A-M-K-K-Q-V-Q-G-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-Q-L-E-H-E-N-L-A-K-T-S-S-K-Q-G-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Y-L-L-I-K-F-V-R-F-W-Q-I-C-I-S-P-L-Y-P-S-S-C-R-F-Y-P-T-C-S-H-Y-A-I-L-S-I-E-K-Y-G-A-F-K-G-G-M-K-A-F-W-R-I-L-R-C-N-P-W-N-K-G-G-I-D-Y-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-M-C-K-K-L-G-R-E-L-P-G-L-A-Y-K-P-F-P-N-E-L-G-Q-R-I-Y-D-S-I-S-Q-D-A-W-K-L-W-L-E-H-F-K-M-I-L-N-E-Y-R-L-A-P-A-D-P-R-T-T-E-I-L-Y-Q-Q-A-E-Q-F-F-F-G-E-N-A-Q-L-P-P-D-Y-R-P-P-P-S-K-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-R-A-A-L-V-L-L-V-R-I-Y-Q-R-L-V-S-P-L-L-P-P-A-C-R-F-Y-P-S-C-S-A-Y-A-V-T-A-L-Q-R-H-G-A-L-R-G-S-W-L-T-V-R-R-L-C-R-C-H-P-F-H-A-G-G-V-D-P-V-P-E-L-T-P-K-R"} +{"text": "### FUNCTION Stationary phase-essential protein not required for growth on nonfermentable carbon sources ### SEQUENCE -M-P-S-F-W-D-S-F-A-V-Y-N-R-N-K-H-A-K-G-D-V-H-G-G-H-M-S-Q-N-M-G-G-Q-P-M-Y-L-Q-A-K-E-H-A-D-I-K-K-K-E-D-G-T-L-E-A-K-I-E-T-P-D-G-P-R-L-V-D-V-S-N-M-T-Q-Q-E-F-E-R-T-Y-N-S-L-R-K-G-E-P-N-N-R-V-N-F"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-T-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-R-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-Y-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-R-G-V-N-E-F-W-Q-Q-L-P-R-S-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-N-N-N-N-V-Y-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-Q-A-E-G-R-P-V-D-I-Q-A-V-T-G-N-M-D-E-E-H-R-D-W-F-C-K-R-Y-A-L-Y-C-Q-Q-A-T-Q-A-K-K-L-E-L-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-P-V-R-F-Y-Q-R-F-I-S-P-V-F-P-P-S-C-R-F-E-L-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-F-K-G-V-L-M-G-L-A-R-I-L-R-C-H-P-W-S-K-T-G-K-D-P-V-P-D-H-F-S-L-K-R-N-Q-E-G-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-L-F-D-A-L-D-D-F-S-Q-Q-L-L-V-T-L-A-D-V-E-A-I-K-K-N-L-K-S-L-V-E-E-N-T-A-L-R-L-E-N-S-K-L-R-E-R-L-G-E-V-E-A-D-A-P-V-K-A-K-H-V-R-E-S-V-R-R-I-Y-R-D-G-F-H-V-C-N-D-F-Y-G-Q-R-R-E-Q-D-E-E-C-M-F-C-D-E-L-L-Y-R-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-Q-I-L-E-R-Y-P-K-D-D-F-L-Q-E-Q-I-E-I-L-T-S-I-D-X-R-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-M-V-Q-C-V-K-L-G-H-E-A-E-G-L-D-R-P-P-Y-P-G-A-L-G-A-R-I-Y-Q-E-V-S-K-E-A-W-Q-G-W-L-K-H-Q-T-M-L-I-N-E-Y-R-L-S-P-I-D-P-K-S-R-T-F-L-E-K-Q-M-E-A-Y-F-F-G-D-G-A-Q-S-P-E-G-Y-V-P-P-A-P-Q-D-S"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-K-G-V-N-E-F-W-Q-Q-L-P-R-S-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-V-R-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-D-P-E-H-R-K-L-L-E-T-E-M-E-G-F-L-F-D-G-K-D-V-V-I-D-G-Y-T-P-P-S-E"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-P-L-S-V-E-Q-A-L-A-N-F-S-Q-R-Y-V-E-A-W-K-A-Q-H-D-C-L-P-I-N-E-E-L-V-G-L-A-S-P-C-I-E-E-T-R-D-L-E-I-S-W-Q-P-I-V-R-D-E-A-I-R-L-H-N-I-E-Q-G-I-E-L-D-L-H-D-D-F-H-A-F-Y-G-T-Q-Y-S-A-D-M-T-A-K-F-E-D-M-N-I-E-L-L-Q-V-W-S-D-E-D-L-E-R-L-Q-G-N-M-L-G-H-L-V-M-Q-R-R-L-K-L-V-P-T-L-F-V-A-V-T-D-D-E-M-E-V-V-S-I-C-N-Q-S-G-E-V-I-L-E-R-V-G-T-K-N-R-T-V-L-A-A-N-M-A-E-F-L-N-K-L-E-P-V-I-A-A"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-R-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-K-G-V-N-E-F-W-Q-Q-L-S-R-S-A"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-K-G-V-N-E-F-W-Q-Q-L-S-R-S-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-N-N-N-N-V-Y-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-Q-A-E-G-R-P-V-D-I-Q-A-V-T-G-N-M-D-E-E-H-R-D-W-F-C-K-R-Y-A-L-Y-C-Q-Q-A-T-Q-A-K-R-L-E-L-E-H"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-K-G-V-N-E-F-W-Q-Q-L-S-R-S-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-N-I-T-N-V-R-I-R-R-V-D-N-K-D-S-S-S-K-L-L-A-Y-V-T-V-T-F-D-D-C-L-V-L-H-N-I-R-V-I-R-G-Q-K-G-V-F-I-V-M-P-N-R-R-T-K-I-G-E-Y-K-D-I-V-H-P-I-N-Q-S-F-R-E-I-L-Q-S-A-I-F-K-E-Y-V-K-E-N-P-S-N-F-E-L-E-L-V"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-N-I-T-N-V-R-I-R-R-V-D-N-K-D-S-S-S-K-L-L-A-Y-V-T-V-T-F-D-D-C-L-V-L-H-N-I-R-V-I-R-G-Q-K-G-V-F-I-V-M-P-N-R-R-T-K-V-G-E-Y-K-D-I-V-H-P-I-N-Q-S-F-R-E-I-L-Q-S-A-I-F-K-E-Y-V-K-E-N-P-A-N-F-E-L-E-L-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-A-G-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-A-E-K-A"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-S-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-H-L-E-H-E-T-V-A-K-N-P-S-K-Q-R-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-P-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-Q-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-K-Q-T-N-N-L-I-T-E-R-T-H-P-C-H-K-P-M-R-H-T-S-H"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-N-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-Q-R-E-A-D-G-Q-D-F-Q-L-Y-P-G-E-L-G-K-R-I-Y-N-E-I-S-K-E-A-W-A-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-S-P-E-H-R-K-L-L-E-Q-E-M-V-Q-F-L-F-E-G-K-D-V-H-I-E-G-Y-T-P-P-E-K-Q"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-H-Q-T-A-E-A-L-R-A-F-T-Q-R-Y-C-A-A-W-Q-Q-Q-R-N-S-L-P-R-S-E-E-L-Y-G-V-P-S-P-C-V-V-D-T-Q-G-E-A-V-F-W-Q-P-Q-P-F-S-L-A-Q-N-I-S-A-V-E-R-A-L-D-I-V-V-Q-Q-P-L-H-S-Y-Y-T-T-Q-F-A-G-D-M-T-G-R-F-A-D-E-T-L-T-L-L-Q-T-W-S-E-E-D-F-Q-R-V-Q-E-N-L-I-G-H-L-V-V-Q-K-R-L-K-L-A-P-T-L-F-I-A-T-L-E-S-G-R-D-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-A-K-R-I-T-L-S-P-S-L-A-S-F-L-S-H-L-E-P-V-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-L-I-V-Y-F-S-S-R-S-E-N-T-H-R-F-V-Q-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-H-L-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-A-I-C-F-L-N-D-V-H-N-R-Q-L-I-R-G-V-I-A-A-G-N-R-N-F-G-D-A-W-G-R-A-G-E-V-I-A-Q-K-C-A-V-P-Y-L-Y-R-F-E-L-M-G-T-P-D-D-I-D-N-V-R-K-G-V-S-E-F-W-Q-R-Q-P-Q-N-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-G-L-L-I-I-L-I-K-F-Y-K-K-F-I-S-P-V-L-P-K-S-C-R-F-Y-P-T-C-S-T-Y-A-L-E-A-I-E-R-F-G-A-F-E-G-G-I-L-A-I-K-R-I-L-R-C-H-P-F-N-P-G-G-Y-D-P-V-P-T-K-E-E-F-L-E-L-K-L-K-R-R-K-N-K"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-T-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-P-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-N-K-N-K-R-W-Y-L-I-A-L-Y-D-I-Y-Q-G-L-L-T-T-K-Q-C-E-Y-F-N-L-H-Y-F-K-D-L-S-F-S-E-I-A-E-L-K-E-V-S-K-S-A-I-S-D-C-L-N-K-V-C-D-Q-L-L-K-Y-E-Q-A-L-L-I-Y-E-K-N-K-K-R-N-D-L-Y-T-L-I-N-D-S-E-L-V-K-K-L-K-D-I"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-G-L-I-V-Y-Y-S-S-R-S-E-N-T-H-R-F-V-A-R-L-G-L-R-A-A-R-I-P-A-G-G-A-D-A-F-H-I-R-E-P-F-V-L-V-V-P-T-Y-S-D-G-D-G-K-G-A-V-P-K-Q-V-I-R-F-L-N-D-A-E-N-R-G-H-I-R-G-V-I-A-A-G-N-S-N-F-G-E-T-Y-G-L-A-G-D-V-I-S-Q-K-C-R-V-P-Y-L-Y-R-F-E-L-I-G-T-E-E-D-V-A-N-V-K-H-G-M-E-R-F-W-T-R-E-Q-L"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-P-L-S-V-E-Q-A-L-A-N-F-S-Q-R-Y-V-E-A-W-K-E-K-H-D-S-L-P-I-N-E-E-L-V-G-L-A-S-P-C-I-D-E-T-R-N-L-E-V-L-W-Q-P-V-A-R-D-E-S-I-R-L-V-N-I-E-N-G-I-E-L-D-L-H-D-D-F-H-A-F-Y-G-A-Q-F-S-A-D-M-T-A-K-F-E-G-M-N-V-E-L-L-Q-I-W-S-D-E-D-L-E-N-L-Q-G-N-M-L-G-H-L-V-M-Q-R-R-L-K-L-V-P-T-L-F-I-A-V-T-D-D-E-M-E-V-I-S-I-C-N-Q-S-G-E-V-I-L-D-T-V-G-T-K-K-R-K-V-L-A-E-S-M-A-E-F-L-E-K-L-E-P-V-V-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-V-L-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-D-P-E-H-R-K-M-L-E-T-E-M-E-G-F-L-F-D-G-K-D-V-V-I-D-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-L-Q-S-W-R-Q-A-L-W-A-L-L-L-L-V-S-V-A-Q-A-Q-F-N-F-F-D-Q-M-F-G-G-G-E-Q-Q-R-Q-Q-Q-R-S-Q-N-S-P-S-D-S-D-R-Y-Q-Q-M-W-N-G-A-Q-C-D-H-Y-L-C-P-G-T-L-A-C-V-H-F-P-H-H-C-P-C-P-H-P-D-V-E-E-K-V-E-L-G-E-G-S-A-V-C-V-S-K-G-G-F-K-A-G-E-A-A-R-K-I-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Makes mgtA transcription sensitive to intracellular proline levels Under low levels of proline this protein cannot be fully translated, and a stem loop forms which permits transcription of the downstream mgtA gene ### SEQUENCE -M-E-P-D-P-T-P-L-P-R-R-R-L-K-L-F-R"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-A-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-T-K-Q-I-I-K-G-I-I-I-E-R-S-S-P-L-K-I-D-E-L-S-Q-A-V-H-L-R-R-E-I-I-I-E-M-V-E-H-R-L-I-E-P-E-G-S-S-P-T-S-W-K-F-D-N-V-C-L-K-R-A-K-I-A-A-S-F-Y-R-D-L-E-I-N-M-P-G-I-A-I-A-L-D-L-L-D-K-I-E-H-L-E-Q-R-L-R-T-L-E-R-F-E-N-Q-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-R-I-F-C-Q-K-L-G-K-E-A-D-A-L-N-Y-S-P-Y-P-G-E-L-G-E-R-I-Y-N-H-I-S-E-Q-A-W-Q-A-W-L-S-H-Q-T-M-L-I-N-E-Y-R-L-S-L-I-D-P-K-A-R-Q-F-L-E-Q-E-M-I-N-F-L-F-G-T-G-S-E-K-P-A-G-Y-T-S-E-K-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-R-I-I-C-Q-K-L-G-K-E-A-D-A-L-N-Y-S-P-Y-P-G-E-L-G-E-R-I-Y-N-H-I-S-E-Q-A-W-Q-A-W-L-S-H-Q-T-M-L-I-N-E-Y-R-L-S-L-I-D-P-K-A-R-Q-F-L-E-Q-E-M-I-N-F-L-F-G-T-G-S-E-K-P-A-G-Y-T-S-E-K-E"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-T-K-Q-I-I-K-G-I-I-I-E-R-S-S-P-L-K-I-D-E-L-S-Q-A-V-H-L-R-R-E-I-I-I-E-M-V-E-H-R-L-I-E-P-E-G-S-S-P-T-S-W-K-F-D-N-V-C-L-K-R-A-K-I-A-A-S-F-Y-R-D-L-E-I-N-M-P-G-I-A-I-A-L-D-L-L-D-K-I-E-H-L-E-Q-R-L-R-T-L-E-R-F-E-N-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-N-N-K-T-P-F-L-S-A-I-F-T-A-S-I-R-G-Y-Q-R-F-F-S-A-F-T-P-S-S-C-R-F-Y-P-T-C-S-N-Y-A-L-W-L-L-Y-F-E-S-P-L-S-A-M-G-K-I-A-I-R-I-L-S-C-N-P-F-C-S-G-G-I-A-Y-P-V-T-R-L-K-R-P-S-L-L-Q-S-H-K-D-F-N-R-N-F-K-T-I-T-F-W-L-V-P-T-A-K-S-R-T-T-Y-Y-I-I-K-V"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-L-A-K-P-L-T-A-I-W-T-L-F-L-L-I-S-T-A-Q-A-Q-F-Q-F-F-E-Q-M-F-G-G-G-G-S-H-Q-G-H-Q-Q-E-Q-E-A-S-S-D-S-S-W-Y-Q-Q-T-W-E-G-T-H-C-T-K-Y-L-C-P-D-T-L-A-C-V-H-F-P-H-H-C-P-C-P-H-P-S-V-E-E-K-V-E-L-G-E-G-S-A-V-C-V-S-R-G-G-W-T-A-G-E-A-A-R-K-I-E-L-A-R-K-G-V-L"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-I-F-Q-S-V-T-S-I-E-E-Q-I-A-H-L-Y-K-Q-L-G-E-L-K-S-Y-L-G-E-L-I-E-E-N-H-R-L-Q-V-E-N-D-H-L-R-R-R-L-E-Q-L-S-E-R-K-V-E-Q-G-K-K-Q-T-K-A-K-L-V-D-I-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-N-V-H-Y-G-S-L-R-T-D-G-D-C-L-F-C-L-S-F-L-N-K-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-Y-D-F-Y-Q-S-L-L-T-P-K-Q-R-N-Y-M-S-L-Y-Y-L-D-D-Y-S-L-G-E-I-A-E-E-Y-E-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-D-Y-E-Q-K-L-L-L-F-Q-K-F-Q-Q-R-H-K-L-L-H-R-L-K-T-H-I-A-E-R-Y-P-N-D-E-E-L-M-K-L-V-L-E-L-E-K-L-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-H-I-F-I-L-L-I-R-F-Y-Q-R-F-I-S-P-L-K-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-I-R-R-F-G-A-L-K-G-G-Y-L-T-I-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-E-K-E-Q-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-A-S-F-K-A-V-M-I-G-G-V-R-W-Y-Q-Q-R-I-S-A-N-T-P-P-C-C-K-Y-Y-P-T-C-S-N-Y-A-I-E-A-L-E-R-Y-G-A-F-K-G-G-V-L-A-V-L-R-L-L-R-C-R-P-W-S-R-G-G-I-D-D-V-P-Q-R-Y-S-I-F-Y-R-F-S-W-S-K-A-H-E-E-P-R-L-T-P-L-A-T-T-Q-R-E-A-Q-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-R-I-L-R-W-F-I-R-L-Y-Q-I-A-I-S-P-L-L-G-P-R-C-R-Y-I-P-T-C-S-Q-Y-A-L-E-A-L-Q-T-H-G-A-I-K-G-V-W-L-S-S-K-R-I-C-R-C-H-P-W-G-G-S-G-Y-D-P-V-P-P-K-A-I-R-F-I-S-F-H-Q-I-D-S-Q-T-H-H-V-A-V-P-F-R-D-R-L-M-K-Q-N-L-S-N-H-L-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-F-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-N-S"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-E-K-K-D-I-F-A-S-V-S-S-M-E-E-Q-I-G-H-L-Y-K-Q-L-G-E-L-K-Q-H-L-A-E-L-L-E-E-N-Q-H-I-K-M-E-N-E-N-L-R-H-R-F-E-E-V-Q-I-K-E-K-Q-K-T-Q-K-R-K-E-V-K-P-K-T-D-I-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-N-L-H-Y-G-S-V-R-K-E-G-D-C-L-F-C-L-S-F-L-N-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-L-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-H-S"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-Q-V-F-C-R-K-Y-Q-K-E-M-E-G-L-D-F-A-P-F-P-G-A-K-G-Q-E-F-F-E-N-V-S-K-Q-A-W-Q-E-W-L-Q-H-Q-T-T-L-I-N-E-K-R-L-N-V-F-E-P-E-A-K-K-F-L-E-E-Q-R-E-K-F-F-N-N-D-E-S-V-E-K-A-E-G-W-K-P-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-R-I-L-R-W-F-I-R-L-Y-Q-I-A-I-S-P-L-L-G-P-R-C-R-Y-I-P-T-C-S-Q-Y-A-L-E-A-L-Q-T-H-G-A-I-K-G-V-W-L-S-S-K-R-I-C-R-C-H-P-W-G-G-S-G-Y-D-P-V-P-P-K-A-I-R-F-I-S-F-H-Q-I-D-S-Q-T-H-H-V-A-V-P-F-R-D-R-L-M-K-Q-N-L-S-N-H-L-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-L-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-N-S"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-D-I-T-D-I-R-I-K-K-V-D-S-K-N-S-G-S-K-L-L-A-Y-V-A-V-T-F-D-N-C-L-V-L-H-N-I-R-V-I-K-G-Q-K-G-V-F-I-A-M-P-N-R-R-T-R-V-G-E-Y-K-D-I-V-H-P-I-S-Q-D-F-R-K-A-L-Q-T-S-I-F-K-E-Y-I-R-E-N-P-A-D-L-E-L-E-L-D-F"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-M-V-Q-C-V-K-L-G-H-E-A-E-G-L-D-R-P-P-Y-P-G-A-L-G-A-R-I-Y-Q-E-V-S-K-E-A-W-Q-G-W-L-K-H-Q-T-M-L-I-N-E-Y-R-L-S-P-I-D-P-K-S-R-T-F-L-E-K-Q-M-E-A-Y-F-F-G-D-G-A-Q-S-P-E-G-Y-V-P-P-A-P-Q-D-S"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-E-K-K-D-I-F-A-S-V-S-S-M-E-E-Q-I-G-H-L-Y-K-Q-L-G-E-L-K-Q-H-L-A-E-L-L-E-E-N-Q-H-I-K-M-E-N-E-N-L-R-H-R-F-E-E-V-Q-I-K-E-K-Q-K-T-Q-K-R-K-E-V-K-P-K-T-D-I-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-N-L-H-Y-G-S-V-R-K-E-G-D-C-L-F-C-L-S-F-L-N-K-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-F-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-N-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-L-L-I-V-L-I-K-G-Y-R-N-F-I-S-P-L-F-P-P-S-C-R-F-Q-P-T-C-S-K-Y-A-L-E-A-V-E-R-F-G-V-L-H-G-G-S-L-A-I-K-R-I-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P-L-V-D-S-S-S-K-R-S-Q"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-I-V-L-I-G-L-I-R-G-Y-R-T-F-I-S-P-L-F-P-P-S-C-R-F-Q-P-T-C-S-Q-Y-G-I-E-A-I-E-R-F-G-A-I-K-G-A-W-L-T-L-G-R-I-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P-P-V-K-P-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-A-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-R-D-F-T-T-R-Y-C-D-A-W-H-E-K-H-H-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-S-D-A-V-Y-W-Q-P-Q-P-F-V-G-E-Q-N-L-A-A-V-E-R-A-F-D-I-V-L-Q-P-A-I-Q-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-A-E-H-T-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-L-F-I-A-T-L-E-N-E-L-D-V-I-S-L-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-N-R-Q-V-L-A-P-S-L-A-E-F-L-K-Q-L-N-P-L-L"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-A-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-T-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-S-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-S-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-S-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-I-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-T-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-V-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-A-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-T-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-A-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-T-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-P-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-S-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-T-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-M-C-R-K-Y-H-E-E-L-P-G-L-D-R-P-P-Y-P-G-A-K-G-E-D-I-Y-N-N-V-S-R-K-A-W-D-E-W-Q-K-H-Q-T-M-L-I-N-E-R-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-Q-E-M-D-K-F-L-S-G-E-D-Y-A-K-A-D-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-F-L-L-I-G-L-I-R-F-Y-Q-Y-A-I-S-P-L-I-G-P-R-C-R-F-Y-P-S-C-S-H-Y-T-L-E-A-I-R-V-H-G-A-L-R-G-G-Y-L-G-A-R-R-L-L-R-C-H-P-W-H-P-G-G-Y-D-P-V-P-E-R-Q-E-Q-A-C-A-C-H-R-T-A-K-P-G-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-P-V-S-P-F-A-W-I-A-L-I-P-I-Y-F-Y-R-W-F-I-S-P-L-I-G-P-R-C-R-F-T-P-T-C-S-L-Y-A-I-E-A-L-K-A-H-G-F-V-K-G-C-W-L-S-G-K-R-L-L-K-C-H-P-L-N-E-G-G-F-D-P-V-P-P-V-Q-K-Q-D-R-D-K"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-T-Q-R-A-Q-D-A-L-L-S-F-S-Q-R-Y-V-D-A-W-Q-Q-Q-H-Q-S-L-P-R-N-E-E-L-V-D-I-V-S-P-C-V-E-E-K-S-G-D-A-V-L-W-K-H-Y-P-R-E-Q-F-A-D-F-T-N-V-E-T-G-I-E-L-T-L-H-E-D-V-K-T-F-Y-G-A-Q-F-S-A-D-M-N-A-T-F-D-G-N-E-L-T-L-L-Q-I-W-S-D-D-D-F-E-C-L-Q-E-N-I-L-G-H-L-V-T-Q-R-R-L-K-L-K-P-T-V-F-I-A-A-T-D-A-E-L-D-V-I-S-I-C-N-L-T-G-N-V-I-L-E-R-L-G-T-K-N-R-D-V-L-A-E-T-L-A-E-F-L-E-K-L-Q-P-A-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-A-R-L-Q-K-D-A-E-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-V-S-K-E-A-W-G-Q-W-Q-S-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-D-P-E-H-R-K-L-L-E-T-E-M-V-N-F-L-F-E-G-K-D-V-V-I-D-G-Y-T-P-P-S-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-K-K-E-A-E-G-L-G-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-V-S-K-E-A-W-A-L-W-Q-S-K-Q-T-M-L-I-N-E-N-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-I-N-F-L-F-E-G-K-D-V-E-I-E-G-Y-V-P-Q-K-D-D-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-T-L-P-R-E-L-V-V-W-P-I-R-C-Y-Q-R-F-I-S-P-C-L-P-P-A-C-R-Y-V-P-T-C-S-A-Y-A-A-E-A-V-L-T-H-G-V-V-R-G-L-L-L-A-C-R-R-L-L-R-C-H-P-W-C-A-G-G-Y-D-P-V-P-P-P-R-H-S-G-C-A-V-P-G-A-S-A-T-A-T-A-R-H-A-T-A-Q-E-L-S-I-S-H-G-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-T-S-F-L-F-E-G-K-E-V-E-I-E-G-F-V-P-E-K-D-Q-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-L-Q-W-L-A-T-T-L-I-R-G-Y-Q-V-F-I-S-P-I-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-K-V-H-G-T-A-K-G-C-W-F-A-L-K-R-I-L-K-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-G-K-Y-D-R-Y-I-S-F-K-N-A-N-W-E-S-Q-S-S-G-V-M-D-G-L-K-P-H-I-E-A-A-D-S-P-F-W-V-Y-F-M-R-Q-R-E-L-A-H-Q-R-G-L-D-D-L-R-V-L-H-N-F-L-P-T-L-R-E-L-L-E-E-L-D-D-Q-P-T-L-A-L-L-E-Q-L-E-E-S-C-M"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-N-V-F-C-A-Y-L-K-Q-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-S-I-S-K-Q-A-W-A-E-W-I-K-K-Q-T-M-L-V-N-E-K-K-L-N-M-M-N-P-E-H-R-Q-L-L-E-T-E-M-V-N-F-L-F-E-G-K-E-V-H-I-E-G-Y-V-P-V-E-S-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-R-W-L-L-L-K-L-I-R-F-Y-Q-V-A-I-S-P-W-T-P-P-S-C-I-Y-T-P-T-C-S-H-Y-G-Y-E-A-I-Q-K-Y-G-A-L-R-G-G-W-M-T-I-K-R-I-A-R-C-H-P-F-A-R-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-N-C-V-L-L-G-K-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-K-K-I-Y-E-G-V-S-K-E-A-W-Q-K-W-V-K-H-Q-T-M-L-I-N-E-Y-R-L-T-P-V-D-P-K-A-R-K-F-L-E-E-E-M-D-K-F-F-F-S-G-G-S-T-K-P-E-G-Y-V-A-P-S-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-F-Y-E-R-T-V-D-L-G-L-R-A-Y-K-L-T-L-S-P-L-I-G-R-Q-C-R-F-T-P-S-C-S-E-Y-T-A-A-A-L-K-D-H-G-P-L-K-G-S-W-L-G-L-R-R-I-C-R-C-N-P-F-G-G-S-G-Y-D-P-P-P-P-R-H-Q-P-R-K-W-K-C-E-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-R-I-L-I-S-I-I-R-F-Y-Q-R-F-I-S-P-I-K-V-R-P-T-C-R-F-Y-P-T-C-S-Q-Y-A-I-E-A-V-T-K-Y-G-C-V-K-G-T-F-L-A-L-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-I-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-L-P-R-R-A-A-H-V-A-I-R-G-Y-Q-L-T-L-S-G-L-V-G-R-Q-C-R-H-W-P-S-C-S-A-Y-T-D-E-A-I-E-R-H-G-L-W-A-G-G-W-M-G-L-A-R-I-C-R-C-G-P-F-G-T-H-G-I-D-L-V-P-E-R-L-P-E-G-A-A-W-H-R-P-W-A-Y-G-R-W-R-G-V-N-A-P-A-T-P-L-A-E-E-V-H-D-P-L-P-G-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-R-A-A-L-V-L-L-V-R-I-Y-Q-R-L-V-S-P-L-L-P-P-A-C-R-F-Y-P-S-C-S-A-Y-A-V-T-A-L-Q-R-H-G-A-L-R-G-S-W-L-T-V-R-R-L-C-R-C-H-P-F-H-A-G-G-V-D-P-V-P-E-L-T-P-K-R"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-L-A-K-P-L-T-A-I-W-T-L-F-L-L-I-S-T-A-Q-A-Q-F-Q-F-F-E-Q-M-F-G-G-G-G-A-Q-Q-G-H-P-H-E-Q-E-A-S-S-D-S-A-W-Y-Q-R-T-W-E-G-A-H-C-T-R-Y-L-C-P-G-T-L-S-C-V-H-F-P-H-H-C-P-C-P-H-P-N-V-E-D-K-V-E-L-G-E-G-S-A-V-C-V-S-R-G-G-F-A-P-G-E-A-A-R-K-I-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-L-H-T-W-I-R-T-L-G-A-L-L-L-L-A-S-V-A-H-A-Q-F-Q-F-F-E-H-M-F-G-G-G-R-Q-E-H-Q-Q-Q-A-A-Q-N-E-P-S-D-S-S-R-Y-Q-N-M-W-E-S-A-Q-C-D-K-Y-L-C-P-G-T-L-A-C-V-H-F-P-H-H-C-P-C-A-H-P-D-N-E-D-K-I-E-L-S-E-G-S-A-V-C-I-S-K-G-G-F-Q-P-G-E-A-A-R-K-I-E-L-A-R-K-G-V-L"} +{"text": "### FUNCTION Cluster 41 protein ### SEQUENCE -M-G-R-W-I-C-M-Y-H-T-V-P-H-A-R-P-S-L-A-D-R-R-V-F-R-I-Q-P-V-T-Q-F-L-A-T-T-T-T-F-Q-H-R-A-S-S-E-A-S-Y-V-P-L-E-P-G-L-L-L-L-C-C-F-Y-P-I-G-N-L-I-L-L-V-R-L-S-L-V-L-R-N-G-S-L-V-L-P-L-S-C-V"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-Q-I-L-E-R-Y-P-K-D-N-F-L-Q-E-Q-I-E-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-P-V-R-F-Y-Q-R-F-I-S-P-V-F-P-P-S-C-R-F-E-L-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-F-K-G-V-L-M-G-L-A-R-I-L-R-C-H-P-W-S-K-T-G-K-D-P-V-P-D-H-F-S-L-K-R-N-Q-E-G-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-L-F-D-A-L-D-D-F-S-Q-Q-L-L-V-T-L-A-D-V-E-A-I-K-K-N-L-K-S-L-V-E-E-N-T-A-L-R-L-E-N-S-K-L-R-E-R-L-G-E-V-E-A-D-A-P-V-K-A-K-H-V-R-E-S-V-R-R-I-Y-R-D-G-F-H-V-C-N-D-F-Y-G-Q-R-R-E-Q-D-E-E-C-M-F-C-D-E-L-L-Y-R-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-Q-A-H-N-L-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-Q-K-L-G-V-P-A-M-R-I-P-L-H-S-R-I-E-V-S-D-P-Y-V-L-V-L-P-T-Y-G-G-G-R-T-A-P-D-L-Q-A-G-G-Y-V-P-K-Q-V-I-A-F-L-N-N-E-Y-N-R-A-L-I-C-G-V-V-A-A-G-N-T-N-F-G-A-E-F-C-Y-A-G-D-V-V-A-R-K-C-G-V-P-Y-L-Y-R-F-E-L-M-G-T-E-D-D-V-T-A-V-R-A-G-L-A-N-L-W-K-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-F-L-G-L-I-W-V-Y-Q-R-F-I-S-P-L-T-P-P-S-C-R-F-Y-P-T-C-S-N-Y-T-K-E-A-I-E-V-H-G-P-I-K-G-A-W-L-G-I-K-R-I-S-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-N-N-H-Q-H-C-E-H-H-H-H"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-S-K-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-A-L-L-T-K-K-Q-R-N-Y-L-E-L-F-Y-L-Q-D-Y-S-L-S-E-I-A-D-T-F-D-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-T-K-L-E-L-Y-S-K-F-E-Q-R-R-E-I-Y-N-Q-M-K-A-S-I-E-D-P-D-A-L-K-R-Y-I-E-E-L-E-E-L-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-S-I-I-I-N-F-V-R-L-Y-Q-K-W-I-S-P-L-F-P-P-S-C-R-Y-R-P-T-C-S-T-Y-M-I-E-A-V-E-K-H-G-I-K-G-V-L-M-G-I-A-R-I-L-R-C-H-P-F-V-E-G-G-E-D-P-V-P-D-E-F-T-L-R-R-N-P-Q-K-G-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-F-L-I-F-L-I-K-V-Y-R-K-Y-I-S-P-L-K-V-P-C-C-R-F-Y-P-T-C-S-Q-Y-V-L-E-A-L-Q-K-H-G-I-I-K-G-G-F-M-S-I-K-R-I-L-R-C-N-P-F-C-K-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-E-R-I-R-L-S-I-L-L-D-I-Y-G-E-L-L-T-E-K-Q-R-N-V-L-D-L-Y-Y-N-Q-D-L-S-L-A-E-I-A-E-H-T-S-T-S-R-Q-A-V-Y-D-I-I-K-R-C-H-M-L-L-V-H-Y-E-D-K-L-N-L-M-E-E-K-K-N-I-E-E-N-K-K-G-I-I-D-F-I-D-S-L-Y-S-D-K-N-A-E-V-L-D-K-I-K-N-Y-I-M-N-N-I"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-L-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-H-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-L-L-I-M-I-V-R-F-Y-Q-K-Y-I-S-P-L-K-P-P-T-C-R-F-E-P-T-C-S-N-Y-F-I-Q-A-L-E-K-H-G-L-L-K-G-L-F-L-G-L-R-R-V-V-R-C-N-P-L-S-K-G-G-Y-D-P-V-P-E-E-F-S-F-K-L-R-R-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-P-L-A-Q-V-L-A-L-P-V-R-A-Y-R-L-L-L-S-P-W-V-G-H-G-C-R-Y-Q-P-T-C-S-V-Y-A-L-D-A-L-E-R-H-G-A-L-K-G-G-W-L-A-A-R-R-I-L-S-C-H-P-W-G-G-S-G-Y-D-P-V-P-G-A-D-P-E-H-D-R-R-P-R-G"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-N-D-Q-T-P-D-R-Y-V-T-F-L-G-L-D-C-D-A-K-A-D-R-L-M-D-M-L-A-V-R-I-Q-E-D-D-S-R-W-V-G-Y-F-R-Q-K-L-A-E-K-E-R-M-A-T-D-N-L-H-F-V-G-S-Q-I-N-S-L-Y-S-Y-F-E-E-L-E-D-A-D-A-L-D-L-L-W-H-L-E-H-N-C-C"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-K-L-A-L-L-L-I-R-F-Y-Q-R-F-I-S-P-G-L-P-P-A-C-R-F-Y-P-T-C-S-E-Y-G-Y-E-A-I-S-R-Y-G-I-I-K-G-G-V-L-T-V-R-R-L-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-R-W-L-L-L-K-L-I-R-F-Y-Q-V-A-I-S-P-W-T-P-P-S-C-I-Y-T-P-T-C-S-H-Y-G-Y-E-A-I-K-K-Y-G-A-L-R-G-G-W-M-T-V-K-R-I-A-R-C-H-P-F-A-R-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-H-C-I-K-L-G-K-E-A-E-G-L-D-F-A-P-Y-P-G-D-L-G-K-R-I-Y-D-N-V-S-K-Q-A-W-A-D-W-I-K-H-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-Q-Y-L-A-R-Q-M-E-N-H-F-F-G-S-G-A-D-A-A-A-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-V-T-D-V-R-I-R-K-I-T-N-E-G-R-M-K-A-I-V-S-V-T-F-D-N-C-F-V-V-H-D-I-K-I-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-E-G-E-F-K-D-I-A-H-P-I-N-Q-E-T-R-D-M-V-Q-K-A-V-I-E-K-Y-E-A-V-I-S-A-G-E"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-F-Q-K-L-I-V-I-T-F-A-I-A-L-A-S-A-N-I-F-D-F-L-N-N-F-N-A-G-G-R-Q-Q-Q-N-Q-G-V-R-T-P-Q-E-Y-E-S-V-V-L-N-S-Q-C-D-K-Y-L-C-P-D-T-G-L-C-V-E-A-P-K-F-C-P-C-P-Y-P-S-S-Q-I-R-C-F-L-P-D-G-R-F-V-C-I-S-K-P-A-G-E-G-I-S-E-K-Y-N-D-P-K-T-N-W-K-I-D-A-K-D-D-N-I-R-D-C-G-W-V-N-R-A-W-R-G-L-V"} +{"text": "### FUNCTION Egg-yolk protein that is a source of nutrients during embryonic development ### SEQUENCE -S-L-E-D-I-E-H-E-V-E-E-L-L-R"} +{"text": "### FUNCTION May be a cell surface adhesion protein ### SEQUENCE -A-P-T-P-A-T-L-N-G-L-T-I-F-A-P-N-D-E-A-F-K-A-T-G-V-P-D-L-S-K-L-S-N-A-P-M-V-S-L-L-Q-Y-H-A-A-A-R"} +{"text": "### FUNCTION Alpha-amylase inhibitor ### SEQUENCE -S-W-C-D-P-A-T-L-K-Y-V-S-G-I-T-G-C-R-A-M-V-K-L-Q-C-L"} +{"text": "### FUNCTION Alpha-amylase inhibitor ### SEQUENCE -S-W-C-D-P-A-T-I-K-Y-V-S-G-L-T-G-C-R-A-M-V-K-L-E-C-L-G-S-Q"} +{"text": "### FUNCTION Exhibits Kunitz trypsin protease inhibitor activity ### SEQUENCE -L-V-L-D-V-D-G-N-P-L-E-V-G-S-E-Y-Y-I-G-R-A-V-G-F-Y-V-V-E-R-F-S-E-V-D-R-G-D-P-L-S-S-D-V-Q-I-D-S-G-L-S-A-Y-C-R-S-D-G-F-W-G-V-P-P-S-S-F-R-I-E-K-T-E-G-F-P-N-A-Y-K-I-A-Y-S-P-P-T-T-S-S-Q-Q-Q-R-Y-P-D-L-H-S-G-L-N-L-V-G-L-T-D-D-S-A-R-V-V-L"} +{"text": "### FUNCTION Exhibits Kunitz trypsin protease inhibitor activity ### SEQUENCE -D-T-D-S-D-L-V-L-D-V-D-G-N-P-L-E-V-G-S-E-Y-Y-I-G-R-A-V-G-F-Y-V-V-E-R-F-S-S-D-V-Q-I-D-S-G-L-C-R-S-D-G-F-W-R-V-S-L-D-A-Y-S-P-P-T-T-T-S-S-Q-Q-Q-R-Y-L-T-V-F-R-D-R-L-S-G-L-K-L-V-G-L-T-D-D-S-D-R-V-V-L"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-G-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-Q-L-E-H-E-N-L-A-K-T-S-S-K-Q-G-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-A-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-E-I-F-D-D-I-L-A-K-Y-P-S-D-H-Y-L-R-D-K-I-S-I-L-T-S-I-D-N-R-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-D-I-E-A-M-K-K-Q-V-Q-G-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-Q-L-E-H-E-N-L-A-K-T-S-S-K-Q-G-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-V-H-I-F-T-S-I-L-L-G-L-L-L-L-A-T-G-T-R-A-Q-F-Q-F-F-E-Q-M-F-G-G-G-Q-Q-Q-Q-Q-H-D-S-R-E-Q-N-V-P-S-D-S-D-W-Y-Q-R-T-Y-D-N-A-R-C-S-N-Y-L-C-P-G-T-L-A-C-V-A-V-P-H-H-C-P-C-Q-H-P-A-V-E-D-K-F-E-L-G-D-G-S-A-I-C-V-S-K-G-G-F-K-F-G-E-A-A-R-K-V-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-K-G-V-N-E-F-W-Q-Q-L-P-R-S-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-K-R-S-I-L-L-L-I-K-V-Y-Q-Y-F-I-S-P-L-T-G-P-T-C-R-F-Y-P-T-C-S-Q-Y-A-F-E-A-V-M-I-H-G-S-L-K-G-S-C-L-A-V-R-R-I-L-K-C-H-P-F-H-P-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-D-R-F-L-I-K-L-I-K-I-Y-K-K-F-V-S-P-A-L-P-N-S-C-R-Y-Y-P-T-C-S-S-Y-A-I-Q-S-I-E-K-Y-G-A-L-K-G-S-L-K-A-V-W-R-I-L-R-C-N-P-F-S-K-G-G-V-D-Y-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-L-I-V-Y-F-S-S-R-S-G-N-T-H-R-F-V-E-R-L-G-V-R-S-S-R-I-P-L-E-A-S-G-A-L-Q-V-R-E-P-F-V-L-V-T-P-T-Y-G-G-G-S-T-K-G-A-V-P-N-P-V-I-R-F-L-N-D-A-D-N-R-A-L-I-R-G-V-I-A-A-G-N-S-N-F-G-E-A-F-C-I-A-G-N-I-I-S-A-K-C-G-V-P-Y-L-Y-R-F-E-L-L-G-T-A-E-D-V-G-N-V-R-N-G-M-E-Q-F-W-T-R-Q-T-Q-A"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-E-I-K-M-F-H-I-L-I-G-A-L-L-G-L-L-F-L-A-T-G-T-R-A-Q-F-Q-F-F-E-Q-M-F-G-G-G-G-H-Q-Q-Q-Q-D-H-R-E-Q-N-V-A-S-D-S-S-W-Y-Q-R-N-Y-D-N-A-H-C-S-D-Y-L-C-P-G-T-L-A-C-V-S-V-P-H-H-C-P-C-Q-H-P-D-V-E-D-K-F-E-L-G-D-G-S-A-I-C-I-S-K-G-G-F-K-A-N-E-A-A-R-K-V-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-V-T-D-V-R-L-R-R-V-N-T-D-G-R-M-K-A-I-A-S-I-T-I-D-H-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-M-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-S-S-T-T-R-E-K-I-Q-A-A-V-L-T-E-Y-D-R-V-G-Q-E-E-E-S-T-I-E-A-G-A"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-D-I-A-G-R-S-L-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-Q-K-L-G-I-P-A-T-R-I-P-L-H-G-R-I-E-V-D-E-P-Y-V-L-I-L-P-T-Y-G-G-G-R-A-N-P-G-L-D-A-G-G-Y-V-P-K-Q-V-I-A-F-L-N-N-D-H-N-R-A-Q-L-R-G-V-I-A-A-G-N-T-N-F-G-A-E-F-C-Y-A-G-D-V-V-S-R-K-C-S-V-P-Y-L-Y-R-F-E-L-M-G-T-E-D-D-V-A-A-V-R-T-G-L-A-E-F-W-K-E-Q-T-C-H-Q-P-S-L-Q-S-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-S-A-L-H-E-S-R-A-D-T-A-E-G-T-S-S-A-S-S-A-W-K-S-V-R-A-L-P-A-R-T-L-I-F-F-I-E-L-Y-R-T-Y-V-S-P-L-R-M-P-T-C-R-F-M-P-T-C-S-E-Y-A-V-E-S-L-R-T-H-G-T-I-K-G-L-L-L-T-V-V-R-L-A-K-C-A-P-W-H-P-G-G-W-D-P-V-P-A-R-H-D-R-H-A-G-S-R-R-C-C-P-A-N-V-D-E-Q-R-S-T"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-L-F-D-A-L-D-D-F-S-Q-Q-L-L-V-T-L-A-D-V-E-A-I-K-K-N-L-K-S-L-V-E-E-N-T-A-L-R-L-E-N-S-K-L-R-E-R-L-G-E-V-E-A-D-A-P-V-K-A-K-H-V-R-E-S-V-R-R-I-Y-R-D-G-F-H-V-C-N-D-F-Y-G-Q-R-R-E-Q-D-E-E-C-M-F-C-D-E-L-L-Y-R-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-Q-I-L-E-R-Y-P-K-D-D-F-L-Q-E-Q-I-E-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-P-V-R-F-Y-Q-R-F-I-S-P-V-F-P-P-S-C-R-F-D-L-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-F-K-G-V-L-M-G-L-A-R-I-L-R-C-H-P-W-S-K-T-G-K-D-P-V-P-D-H-F-S-L-K-R-N-Q-E-G-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-L-F-D-A-L-D-D-F-S-Q-Q-L-L-V-T-L-A-D-V-E-A-I-K-K-N-L-K-S-L-V-E-E-N-T-A-L-R-L-E-N-S-K-L-R-E-R-L-G-E-V-E-A-D-A-P-V-K-A-K-H-V-R-E-S-V-R-R-I-Y-R-D-G-F-H-V-C-N-D-F-Y-G-Q-R-R-E-Q-D-E-E-C-M-F-C-D-E-L-L-Y-R-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-Q-I-L-E-R-Y-P-K-D-N-F-L-Q-E-Q-I-E-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-P-V-R-F-Y-Q-R-F-I-S-P-V-F-P-P-S-C-R-F-E-L-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-F-K-G-V-L-M-G-L-A-R-I-L-R-C-H-P-W-S-K-T-G-K-D-P-V-P-D-H-F-S-L-K-R-N-Q-E-G-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-L-F-D-A-L-D-D-F-S-Q-Q-L-L-V-T-L-A-D-V-E-A-I-K-K-N-L-K-S-L-V-E-E-N-T-A-L-R-L-E-N-S-K-L-R-E-R-L-G-E-V-E-A-D-A-P-V-K-A-K-H-V-R-E-S-V-R-R-I-Y-R-D-G-F-H-V-C-N-D-F-Y-G-Q-R-R-E-Q-D-E-E-C-M-F-C-D-E-L-L-Y-R-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-Q-I-L-E-R-Y-P-K-D-N-F-L-Q-E-Q-I-E-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-P-V-R-F-Y-Q-R-F-I-S-P-V-F-P-P-S-C-R-F-E-L-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-F-K-G-V-L-M-G-L-S-R-I-L-R-C-H-P-W-S-K-T-G-K-D-P-V-P-D-R-F-S-L-K-R-N-Q-E-G-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-Q-I-L-E-R-Y-P-K-D-N-F-L-Q-E-Q-I-E-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-L-F-D-A-L-D-D-F-S-Q-Q-L-L-V-T-L-A-D-V-E-A-I-K-K-N-L-K-S-L-V-E-E-N-T-A-L-R-L-E-N-S-K-L-R-E-R-L-G-E-V-E-A-D-A-P-V-K-A-K-H-V-R-E-S-V-R-R-I-Y-R-D-G-F-H-V-C-N-D-F-Y-G-Q-R-R-E-Q-D-E-E-C-M-F-C-D-E-L-L-Y-R-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-L-V-R-F-Y-Q-R-F-I-S-P-V-F-P-P-S-C-R-F-E-L-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-F-K-G-V-L-M-G-L-A-R-I-L-R-C-H-P-W-S-K-T-G-K-D-P-V-P-D-H-F-S-L-K-R-N-Q-E-G-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-L-A-S-R-G-L-V-R-V-I-R-A-Y-Q-R-E-L-S-P-R-K-P-S-P-T-C-R-F-I-P-T-C-S-Q-Y-A-V-E-A-I-E-R-H-G-A-L-K-G-G-W-L-A-T-W-R-I-M-R-C-N-P-L-V-P-G-G-V-D-P-V-P-E-R-F-P-Q-G-R-K-T-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-R-I-V-L-A-L-I-R-F-Y-Q-L-A-I-S-P-W-L-P-P-R-C-R-Y-Q-P-T-C-S-Q-Y-A-I-E-A-V-Q-K-H-G-A-L-K-G-G-W-L-A-L-R-R-I-G-R-C-H-P-W-G-S-S-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-Q-C-I-K-L-G-R-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-K-V-Y-E-N-V-S-K-E-A-W-Q-A-W-L-R-H-Q-T-M-L-I-N-E-N-R-L-N-L-A-D-S-R-A-R-Q-Y-L-T-Q-Q-L-Q-N-Y-F-F-G-T-G-A-D-M-P-A-G-F-V-P-P-S-V"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-S-T-T-T-Y-R-S-I-C-G-E-E-S-L-P-Y-I-D-C-D-R-C-I-R-A-L-Y-A-R-L-Q-H-Y-V-Q-Q-D-R-G-D-C-P-I-C-A-Y-F-R-E-K-I-G-S-R-D-G-S-E-S-D-A-R-L-L-L-H-A-Q-V-N-V-V-Y-E-L-F-A-R-H-A-D-Q-E-A-L-A-L-L-E-R-I-E-D-D-C-C"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-H-C-R-K-Y-K-E-E-L-P-G-L-D-R-P-P-Y-P-G-P-K-G-E-D-I-Y-N-N-V-S-R-Q-A-W-D-E-W-Q-K-H-Q-T-M-L-I-N-E-R-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-A-E-M-E-K-F-L-S-G-E-E-Y-A-Q-A-E-G-Y-V-Q-P-K-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-L-A-L-A-A-I-Q-F-Y-R-Y-A-I-S-P-L-M-A-N-H-C-R-F-H-P-S-C-S-C-Y-A-H-E-A-I-S-T-H-G-L-L-R-G-G-W-L-S-L-R-R-L-G-R-C-H-P-W-N-P-G-G-Y-D-P-V-P-P-I-K-T-S-R-S-S-S-M-A-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-D-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-E-K-K-D-I-F-A-S-V-S-S-M-E-E-Q-I-G-H-L-Y-K-Q-L-G-E-L-K-Q-H-L-A-E-L-L-E-E-N-Q-H-I-K-M-E-N-E-N-L-R-H-R-F-E-E-V-Q-I-K-E-K-Q-K-T-Q-K-R-K-E-V-K-P-K-T-D-I-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-N-L-H-Y-G-S-V-R-K-E-G-D-C-L-F-C-L-S-F-L-N-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-F-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-N-S"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-H-N-V-F-C-A-R-Y-K-Q-E-M-E-G-L-D-E-P-P-F-D-S-D-F-G-H-K-I-Y-N-N-V-S-K-R-A-W-G-E-W-I-E-H-Q-K-M-L-L-N-E-Y-R-L-Q-P-W-T-P-Q-A-Q-E-F-L-V-E-Q-M-N-Q-Y-F-F-G-E-G-A-Q-L-P-K-E-Y-V-P-P-S-P-R"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-V-R-K-I-A-A-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-Y-K-D-I-A-H-P-I-N-T-E-T-R-E-K-I-Q-K-S-I-I-E-E-Y-E-R-A-K-M-E-E-E-S-S-E-K-V-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-L-L-I-C-I-I-K-M-Y-R-K-Y-I-S-P-L-K-R-P-S-C-R-F-Y-P-T-C-S-Q-Y-S-L-E-A-I-E-K-Y-G-A-L-K-G-T-L-I-S-I-K-R-I-L-K-C-H-P-F-N-E-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-E-I-V-E-M-S-L-L-L-D-F-Y-G-S-L-L-T-E-K-Q-N-K-I-M-D-L-Y-Y-N-N-D-Y-S-L-K-E-I-S-E-L-T-N-T-S-R-Q-A-V-H-D-I-V-K-R-C-H-K-A-L-L-Q-Y-E-E-K-L-H-M-M-E-R-F-I-N-L-E-N-S-K-E-K-L-L-N-M-L-N-K-V-T-K-E-N-I-K-E-I-D-H-I-K-K-Y-I-I-D-N-I"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-F-E-K-T-N-R-M-N-L-L-F-D-F-Y-Q-E-L-L-T-T-K-Q-K-A-Y-V-S-F-Y-Y-L-D-D-Y-S-L-G-E-I-A-E-E-F-E-V-S-R-Q-A-I-Y-D-N-I-K-R-T-E-E-S-L-E-K-Y-E-E-K-L-G-M-L-K-K-Y-Q-Q-R-E-K-L-F-S-Q-L-E-A-Q-L-T-K-K-N-F-L-D-E-Q-V-K-D-T-L-E-Q-L-K-N-I-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-A-I-F-D-S-V-S-N-M-E-E-Q-I-G-E-L-Y-Q-Q-L-G-D-L-K-T-N-L-G-E-M-L-E-E-N-N-R-L-N-L-E-N-E-H-L-R-R-R-L-S-L-T-D-E-A-T-P-E-P-K-A-E-I-E-A-E-H-G-V-M-A-P-N-R-K-E-A-M-Q-Q-M-I-E-L-G-E-G-Y-D-N-L-V-Q-L-Y-K-E-G-F-H-V-C-N-V-H-F-G-S-P-R-G-N-D-E-D-C-L-F-C-L-S-L-L-N-K-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-I-I-C-R-K-Y-K-E-E-L-P-G-L-E-R-P-P-Y-P-G-A-K-G-Q-D-I-F-D-H-V-S-A-K-A-W-G-D-W-L-K-H-Q-T-L-L-I-N-E-K-R-L-N-M-M-N-A-E-D-R-K-Y-L-A-G-E-M-D-K-F-F-S-G-E-E-Y-A-K-A-D-G-Y-V-P-P-A-Q"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-R-V-R-K-I-A-A-E-G-K-M-K-A-I-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-Y-K-D-I-A-H-P-I-N-T-E-T-R-E-K-I-Q-K-S-I-I-E-E-Y-E-R-A-K-M-E-E-E-S-S-E-K-V-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-L-L-I-C-I-I-K-M-Y-R-K-Y-I-S-S-L-K-R-P-S-C-R-F-Y-P-T-C-S-Q-Y-S-I-E-A-I-E-K-Y-G-A-L-K-G-T-L-I-S-I-K-R-I-L-K-C-H-P-F-N-E-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-E-I-V-E-M-S-L-L-L-D-F-Y-G-S-L-L-T-E-K-Q-N-K-I-M-D-L-Y-Y-N-N-D-Y-S-L-K-E-I-S-E-L-T-N-T-S-R-Q-A-V-H-D-I-V-K-R-C-H-K-A-L-I-Q-Y-E-E-K-L-H-M-M-E-R-F-I-N-L-E-N-S-K-E-K-L-L-N-M-L-N-K-V-T-K-E-N-I-K-E-I-D-H-I-K-K-Y-I-I-D-N-I"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-F-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-N-S"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-E-K-K-D-I-F-A-S-V-S-S-M-E-E-Q-I-G-H-L-Y-K-Q-L-G-E-L-K-Q-H-L-A-E-L-L-E-E-N-Q-H-I-K-M-E-N-E-N-L-R-H-R-F-E-E-V-Q-I-K-E-K-Q-K-T-Q-K-R-K-E-V-K-P-K-T-D-I-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-N-L-H-Y-G-S-V-R-K-E-G-D-C-L-F-C-L-S-F-L-N-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-T-P-L-S-P-F-S-W-L-A-I-G-I-V-K-L-Y-Q-W-F-I-S-P-L-I-G-P-R-C-R-F-T-P-T-C-S-T-Y-A-I-E-A-L-R-A-H-G-F-I-K-G-C-W-L-S-T-K-R-L-L-K-C-H-P-L-N-E-G-G-F-D-P-V-P-P-V-Q-K-Q-D-R-D-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-T-R-L-Q-K-E-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-C-K-E-A-W-A-Q-W-Q-T-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-D-P-E-H-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-K-E-V-H-I-E-G-Y-T-P-P-A-K"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-A-K-T-I-T-I-S-E-E-A-Y-K-L-L-L-K-E-K-R-D-G-E-S-F-S-D-V-I-V-R-L-I-K-G-N-R-R-E-V-M-D-Y-A-G-I-W-S-D-M-N-D-E-E-S-N-K-L-F-K-D-L-E-K-M-W-E-R-W-N-V-N-A"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-E-K-K-D-I-F-A-S-V-S-S-M-E-E-Q-I-G-H-L-Y-K-Q-L-G-E-L-K-Q-H-L-A-E-L-L-E-E-N-Q-H-I-K-M-E-N-E-N-L-R-H-R-F-E-E-V-Q-I-K-E-K-Q-K-T-Q-K-R-K-E-V-K-P-K-T-D-I-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-N-L-H-Y-G-S-V-R-K-E-G-D-C-L-F-C-L-S-F-L-N-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-F-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-N-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-R-I-L-L-L-L-L-G-F-Y-Q-Y-F-I-S-P-L-L-G-N-N-C-R-F-H-P-T-C-S-E-Y-A-K-E-A-I-S-M-H-G-S-I-K-G-L-W-F-T-F-K-R-I-I-K-C-Q-P-F-C-N-G-G-Y-D-T-V-P-I-S-I-K-N-S-K-P-L-N-K-K-I"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-R-I-L-L-L-L-L-R-F-Y-Q-Y-F-I-S-P-L-L-G-N-N-C-R-F-H-L-T-C-S-E-Y-A-K-E-A-I-S-M-H-G-S-I-K-G-L-W-F-T-F-K-R-I-I-K-C-Q-P-F-C-D-G-G-Y-D-T-V-P-I-S-I-K-N-S-K-P-L-N-K-K-I"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-K-K-E-A-I-G-Q-D-F-Q-I-Y-P-G-D-I-G-R-R-I-Y-D-D-I-S-Q-E-A-W-S-L-W-L-N-K-Q-T-M-L-I-N-E-K-K-L-S-M-I-H-H-E-D-R-A-L-L-E-R-E-M-I-Q-F-L-F-E-G-K-D-V-H-V-S-G-Y-I-P-P-K-D"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-V-K-I-R-K-V-A-T-E-G-R-M-K-A-L-A-S-I-T-L-D-H-E-F-V-V-H-D-L-R-I-I-E-G-S-S-G-L-F-V-A-M-P-S-K-R-T-P-E-G-I-F-R-D-I-A-H-P-I-N-G-E-M-R-Q-K-V-E-A-A-V-L-E-T-Y-S-N-M-D-V-E-I-L-D-P-Q-H-V-S-Y-G-T-H-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-V-L-V-K-G-I-Q-G-Y-Q-R-F-I-S-P-L-K-P-P-T-C-R-F-Y-P-S-C-S-H-Y-G-I-E-A-I-E-K-H-G-A-V-K-G-S-Y-L-T-A-R-R-L-I-R-C-Q-P-F-H-P-G-G-L-D-Y-V-P-D-T-F-D-W-K-A-P-L-Q-R-E-K-P-E-S-Q-R-D-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-T-L-E-K-T-N-R-M-N-Y-L-I-D-F-Y-Q-A-L-L-T-P-K-Q-R-N-Y-M-S-L-Y-Y-L-D-D-Y-S-L-G-E-I-A-E-E-F-E-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-T-M-L-E-Q-Y-E-E-K-L-A-L-F-E-K-F-E-Q-R-Q-Q-L-L-Q-T-L-K-R-Q-V-E-L-T-D-D-V-S-A-T-I-S-A-L-E-N-L-E"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-A-D-Q-V-I-C-A-L-S-D-V-F-A-R-W-F-A-Y-Q-Q-Q-R-G-I-Q-V-C-C-P-E-D-E-L-R-P-S-P-C-R-Y-D-A-Q-H-P-E-R-W-K-P-W-S-R-P-E-M-S-D-L-Q-N-I-A-S-A-L-E-C-V-F-H-P-A-I-H-A-Y-Y-G-H-G-Y-A-G-Q-I-T-A-S-F-K-G-L-A-V-T-L-V-Q-P-W-N-E-E-D-F-E-R-L-Q-Q-N-L-V-A-H-V-L-M-L-R-R-L-K-L-P-I-T-L-F-L-A-T-V-S-D-E-S-R-V-I-S-L-D-N-E-T-G-E-V-V-L-E-Q-L-G-K-K-K-R-W-V-L-A-D-S-L-P-A-F-L-Q-R-L-S-P-L-A-Q-T-A-V-T-P-A-V-P-V-N-L-P-A"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-P-C-S-C-K-Q-K-K-A-T-P-S-D-I-T-T-D-R-Y-I-T-F-D-G-I-D-C-D-G-N-A-R-I-L-M-S-Y-I-H-K-H-I-D-D-P-Q-K-T-N-K-F-W-D-Y-F-R-K-K-A-E-G-G-N-G-P-K-P-D-D-L-F-L-I-H-S-N-L-N-Q-I-R-E-L-F-E-L-Y-E-D-S-E-A-L-A-L-L-D-V-V-E-I-E-C-C"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-M-V-F-C-Q-R-L-K-K-E-A-P-G-M-A-F-Q-L-V-P-G-E-L-G-K-R-I-F-D-N-I-C-Q-E-A-W-A-E-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-A-E-H-R-A-L-L-Q-T-E-M-E-K-Y-L-F-E-D-G-D-V-Q-I-E-G-Y-V-P-P-S-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-H-P-R-T-P-Q-Q-R-L-A-V-A-L-I-R-V-Y-Q-W-V-I-S-P-L-L-G-P-R-C-R-F-T-P-T-C-S-Q-Y-M-I-N-A-I-C-L-H-G-L-I-K-G-I-W-L-G-G-K-R-L-L-K-C-H-P-L-H-S-G-G-H-D-P-V-P-Q-P-Q-Q-S-K-R-R-K"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-R-G-F-V-V-A-T-I-I-V-G-A-A-N-C-V-M-A-F-D-F-E-Q-F-F-G-G-Q-N-R-Q-Q-Q-R-T-Q-Q-N-N-Q-P-Q-D-Y-E-Q-Q-Q-L-N-S-D-C-Q-K-Y-L-C-P-E-T-F-A-C-V-A-K-P-V-D-C-P-C-P-F-P-Q-S-Q-I-K-C-V-F-P-D-K-Q-N-F-V-C-I-S-S-P-V-D-N-V-N-G-V-P-V-R-D-C-K-W-V-E-K-A-W-K-G-L-L"} +{"text": "### FUNCTION Involved in ribosome biogenesis, probably through modulation of rDNA transcription ### SEQUENCE -M-A-F-S-S-A-S-S-K-A-R-S-K-A-S-V-N-K-L-F-E-S-M-L-P-G-T-S-L-L-P-S-S-S-G-K-S-S-A-T-E-K-F-A-A-Q-V-N-K-K-K-L-T-K-H-E-I-Q-K-A-H-K-V-E-K-A-K-K-N-K-L-I-N-Q-K-L-E-K-E-K-K-F-K-K-L-V-K-F-N-V-I-K-A-H-K-E-E-K-D-L-T-P-E-E-Q-K-Y-L-K-K-L-I-K-K-N-A-N-A-V-V-R-A-S-E-V-D-D-P-F-V-K-D-E-I-D-A-L-R-S-E-I-L-A-L-T-N-E-K-Y-D-K-S-R-D-R-K-L-D-A-K-L-Q-S-F-N-D-K-I-K-K-G-V-L-A-Y-P-G-L-T-P-G-L-A-P-V-G-Y-D-D-E-S-D-E-E"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-F-R-I-L-Y-L-F-V-L-C-G-A-V-S-A-S-I-F-N-F-M-H-D-Q-Y-Q-H-Q-E-P-R-H-E-V-S-F-E-Q-R-V-L-E-S-N-C-D-K-Y-L-C-P-G-T-L-E-C-V-A-R-P-Q-D-C-P-C-P-Y-P-S-S-Q-M-R-C-V-L-P-N-G-D-P-L-C-I-S-K-P-T-G-D-Y-N-G-K-Y-D-D-P-A-K-N-W-K-V-D-A-K-D-D-N-V-R-D-C-G-W-V-K-R-A-W-E-G-R-V"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-F-Q-K-L-I-V-I-T-F-A-I-A-L-A-S-A-N-I-F-D-F-L-N-N-F-N-T-G-G-R-Q-Q-Q-N-Q-G-V-R-T-P-Q-E-Y-E-S-V-V-L-N-S-Q-C-D-K-Y-L-C-P-D-T-G-L-C-V-E-A-P-K-F-C-P-C-P-Y-P-S-S-Q-I-R-C-F-L-P-D-G-R-F-V-C-I-S-K-P-A-G-E-G-I-S-E-K-Y-N-D-P-K-T-N-W-K-I-D-A-K-D-D-N-I-R-D-C-G-W-V-N-R-A-W-R-G-L-V"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-N-I-T-D-V-R-V-R-K-I-A-K-E-G-K-M-R-A-V-V-S-I-T-I-D-D-E-F-V-V-H-D-I-K-V-I-E-G-E-K-G-L-F-I-A-M-P-S-R-K-S-S-D-G-E-Y-R-D-I-A-H-P-I-N-T-Q-T-R-D-K-L-Q-K-I-V-L-E-A-Y-E-K-A-E-Y-V-E-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-E-K-L-E-Q-A-Y-L-Y-D-F-Y-G-E-L-L-N-E-H-Q-R-Q-V-Y-E-D-F-V-F-N-D-L-S-L-G-E-I-A-S-E-E-G-I-S-R-Q-G-V-A-D-L-I-K-R-C-N-K-K-L-L-D-Y-E-A-K-L-H-L-V-E-K-F-M-S-I-K-S-D-I-R-R-I-H-E-L-T-N-D-F-K-K-S-H-N-E-L-L-M-N-E-I-E-A-I-S-N-Q-I-L-E-E-L"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-I-T-D-I-R-I-R-K-V-E-K-E-G-K-M-K-A-V-V-S-I-T-I-D-D-E-F-V-V-H-D-I-K-V-I-E-G-E-K-G-L-F-I-A-M-P-S-R-K-A-N-D-G-E-Y-R-D-I-A-H-P-I-N-S-A-T-R-E-N-I-Q-N-M-I-L-E-K-Y-K-T-E-I-E-N-V"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-A-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-T-F-L-N-R-E-A-E-G-L-D-F-Q-S-Y-P-G-D-L-G-K-R-I-Y-D-H-I-S-K-E-A-W-G-Q-W-M-A-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-P-D-D-R-S-L-L-A-R-E-M-E-K-F-L-F-E-G-H-D-V-H-I-E-G-Y-T-P-P-N-Q"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-E-H-Q-V-S-A-A-L-R-E-F-T-Q-R-Y-V-A-Q-W-Q-Q-Q-H-G-D-W-P-S-S-H-A-L-Y-G-I-P-S-P-C-V-V-Y-S-R-D-D-C-V-F-W-R-P-E-P-G-R-G-E-D-L-E-G-I-G-R-A-L-D-I-R-L-H-P-A-L-A-P-F-F-T-T-Q-Y-A-G-D-M-R-A-R-W-N-E-I-E-M-D-L-V-Q-V-W-S-V-E-D-L-H-R-L-Q-E-N-Q-I-G-H-L-V-T-Q-R-R-L-K-L-S-P-T-L-F-L-A-S-T-A-D-E-L-S-M-V-T-L-C-N-L-S-G-S-V-L-L-E-Q-F-G-S-P-Q-R-R-V-L-A-Q-T-L-T-E-F-L-A-E-L-Q-P-L-A-Q-E-V-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-H-C-R-K-Y-N-K-E-M-E-G-L-A-V-P-P-L-P-G-A-K-G-T-E-L-F-N-S-V-S-K-Q-A-W-Q-E-W-L-Q-H-Q-T-M-L-I-N-E-K-Q-L-N-L-M-D-L-T-A-R-A-Y-L-T-E-Q-M-E-K-F-L-S-G-A-D-Y-D-Q-A-D-G-Y-V-P-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-V-L-T-L-I-N-F-Y-R-K-Y-I-S-P-S-K-P-P-T-C-R-F-T-P-T-C-S-A-Y-T-F-E-A-V-Q-R-F-G-V-F-K-G-L-L-L-G-T-W-R-I-L-R-C-N-P-F-N-K-G-G-Y-D-P-V-P-E-E-F-K-L-L-R-R-N-T-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-Q-C-I-K-L-G-K-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-K-R-L-W-E-N-V-S-K-E-A-W-A-A-W-L-K-Q-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-L-R-A-R-Q-Y-L-A-R-Q-M-E-K-H-F-F-G-E-G-A-D-V-A-Q-G-Y-V-P-P-S-N"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-I-F-Q-S-V-T-S-M-E-E-Q-L-S-H-L-Y-R-Q-L-V-Q-L-K-E-H-V-V-Q-L-L-E-E-N-H-H-L-Q-I-E-N-D-H-L-R-R-R-L-E-Q-V-T-S-E-L-A-E-E-K-Q-K-E-K-D-H-K-H-G-H-E-R-K-L-V-D-I-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-H-V-H-Y-G-S-V-R-K-E-G-D-C-L-F-C-L-S-F-L-N-K-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-V-T-D-V-R-L-R-R-V-N-T-E-G-R-M-K-A-I-A-S-I-T-L-D-N-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-A-T-R-G-K-I-Q-E-A-I-L-A-E-Y-H-R-L-G-K-L-E-E-E-L-E-E-A-G-A-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-L-I-S-F-I-R-F-Y-Q-I-F-I-S-P-L-K-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-V-K-R-F-G-A-I-K-G-G-W-L-T-I-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-E-K-Q-E-N-G-K-S"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-M-R-M-N-Y-L-Y-D-F-Y-Q-A-L-L-T-P-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-Y-S-L-G-E-I-A-Q-Q-Y-E-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-K-K-L-S-L-F-Q-K-F-Q-K-R-K-Q-L-M-N-Q-L-K-D-Y-V-L-Q-K-Y-G-E-D-K-Q-L-F-D-M-I-K-E-L-E-E-L-E"} +{"text": "### FUNCTION Stationary phase-essential protein not required for growth on nonfermentable carbon sources ### SEQUENCE -M-G-G-I-F-D-A-F-E-V-Y-N-K-K-K-H-S-S-N-P-H-M-F-G-N-T-S-N-T-G-G-T-K-T-D-Y-V-Y-S-S-E-Y-R-A-P-K-K-N-K-L-M-K-D-E-L-L-A-P-D-S-E-H-A-D-G-A-K-A-M-L-T-E-S-A-A-Q-A-G-T-P-N-M-V-D-L-S-K-L-S-Q-H-E-L-E-S-L-M-K-D-L-R-K-G-E-P-N-N-R-V-N-F"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-R-G-S-S-L-G-L-Y-F-I-L-P-I-A-S-G-F-F-F-D-F-N-Q-R-N-Q-H-E-G-Q-Q-P-Q-V-S-Y-E-D-K-V-L-N-N-D-C-A-D-F-L-C-P-D-T-L-T-C-V-K-T-A-K-D-C-P-C-P-F-P-K-S-Q-L-R-C-T-L-P-N-G-Q-F-V-C-I-S-K-P-A-T-H-D-K-N-L-N-A-I-Y-D-D-P-V-K-G-P-Q-S-K-I-K-G-L-R-D-C-G-W-V-Q-D-A-Y-K-G-I-V"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-N-C-A-C-R-V-I-A-V-C-L-L-L-V-Q-V-S-G-F-L-F-N-F-N-Q-D-P-P-T-P-P-Q-P-Y-E-D-K-F-L-N-S-G-C-E-G-Y-L-C-P-D-T-L-E-C-V-S-H-V-K-E-C-P-C-P-F-P-K-S-Q-L-K-C-T-L-P-N-N-Q-Y-I-C-I-S-K-P-A-T-H-D-E-K-L-N-A-I-Y-D-D-P-A-K-G-P-K-A-K-N-K-G-I-R-D-C-G-W-V-L-E-A-Y-K-D-Q-V"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-L-R-T-A-L-L-G-L-L-F-I-T-T-A-K-A-Q-F-Q-F-F-E-Q-M-F-G-G-G-Q-Q-H-Q-E-S-S-S-Q-G-G-N-V-P-S-D-S-A-W-Y-Q-N-T-Y-N-G-A-Q-C-S-N-Y-L-C-P-G-T-L-A-C-V-A-V-P-H-H-C-P-C-A-H-P-Q-V-E-D-K-F-E-F-G-E-G-S-A-I-C-A-S-K-G-G-F-K-A-G-E-T-A-R-K-I-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-I-H-I-I-T-G-T-L-L-G-L-L-F-L-A-T-G-A-R-A-Q-F-Q-F-F-E-Q-M-F-G-G-G-Q-Q-Q-Q-E-S-Q-E-H-N-V-P-S-D-S-S-W-Y-Q-R-T-Y-D-N-A-R-C-S-D-Y-L-C-P-G-T-L-A-C-V-S-V-P-H-H-C-P-C-Q-H-P-G-V-E-D-K-F-E-L-G-D-G-S-A-I-C-V-S-K-G-G-F-K-P-G-E-A-A-R-K-V-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-Q-Y-L-L-V-A-L-S-L-F-I-S-L-S-S-A-N-L-F-D-F-L-N-N-F-N-H-G-G-G-G-R-Q-Q-Q-Q-G-A-R-N-P-Q-E-Y-E-N-R-I-L-N-S-Q-C-D-Q-Y-L-C-P-D-T-G-L-C-V-E-S-P-K-F-C-P-C-P-Y-P-S-S-Q-I-R-C-F-L-P-D-G-R-F-V-C-I-S-K-P-A-G-E-G-I-S-D-K-Y-N-D-P-K-T-N-W-K-I-D-A-K-D-D-N-I-R-D-C-G-W-V-N-R-A-W-R-G-L-V"} +{"text": "### FUNCTION Involved in ribosome biogenesis, probably through modulation of rDNA transcription ### SEQUENCE -M-S-S-S-F-S-S-D-A-S-Q-Y-Q-A-E-N-T-V-N-K-L-F-S-N-I-L-H-T-N-I-S-T-T-K-S-T-T-N-A-N-Q-L-F-A-Q-H-G-S-S-V-K-K-N-K-K-N-E-A-K-R-I-K-K-N-E-E-R-T-K-A-F-N-K-F-V-K-Y-N-Y-I-K-N-K-E-N-K-N-E-S-D-K-K-Y-L-S-K-L-V-R-K-N-V-N-K-L-N-S-S-S-K-I-D-D-F-E-I-N-E-E-F-N-I-V-S-S-E-L-L-D-Q-I-K-P-K-N-G-K-R-L-R-K-K-L-F-R-V-N-E-N-D-E-R-A-K-E-F-N-E-K-L-Q-K-G-V-I-S-Y-P-G-L-T-P-G-L-A-P-V-D-Y-N-E-S-D-S-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-Q-R-D-A-E-G-Q-D-F-Q-L-Y-P-G-D-L-G-K-R-I-Y-N-E-I-S-K-E-A-W-A-Q-W-Q-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-V-D-D-R-K-L-L-E-Q-E-M-I-K-F-L-F-E-G-K-D-V-H-I-E-G-Y-T-P-P-S-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-E-H-E-V-V-S-A-L-A-A-F-T-Q-R-Y-V-D-C-W-Q-Q-E-K-G-H-L-P-A-S-E-A-L-Y-G-I-P-S-P-C-I-V-E-N-H-E-D-T-V-Y-W-S-P-Q-P-F-A-P-A-A-A-L-D-G-V-E-R-A-L-E-I-S-L-H-P-D-V-H-A-F-Y-T-A-Q-Y-A-G-D-M-A-A-Q-F-D-S-L-S-C-Q-L-L-Q-V-W-S-E-D-D-F-T-R-M-Q-E-N-L-I-G-H-L-L-T-Q-K-R-L-K-L-T-P-T-L-F-L-A-T-T-D-S-E-M-T-M-V-S-L-C-N-I-S-G-E-I-I-L-E-E-F-G-T-K-K-R-Q-I-L-A-P-T-L-A-A-F-L-F-G-L-N-P-L-A-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-Q-I-F-I-G-L-V-V-F-Y-Q-R-F-I-S-P-L-K-A-P-S-C-R-F-Y-P-T-C-S-H-Y-S-L-Q-A-L-E-K-Y-G-P-V-K-G-L-W-L-T-A-A-R-V-L-K-C-H-P-F-H-P-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-V-H-I-F-T-G-I-L-L-G-L-L-L-L-A-T-G-T-Q-A-Q-F-Q-F-F-E-Q-M-F-G-G-G-Q-Q-Q-Q-H-D-S-R-E-Q-N-V-P-S-D-S-D-W-Y-Q-R-T-Y-D-N-A-R-C-S-N-Y-L-C-P-G-T-L-A-C-V-A-V-P-H-H-C-P-C-Q-H-P-A-V-E-D-K-F-E-L-G-D-G-S-A-I-C-V-S-K-G-G-F-K-F-G-E-A-A-R-K-V-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Makes mgtA transcription sensitive to intracellular proline levels Under low levels of proline this protein cannot be fully translated, and a stem loop forms which permits transcription of the downstream mgtA gene ### SEQUENCE -M-E-P-D-P-T-P-L-P-R-R-R-L-K-L-F-R"} +{"text": "### FUNCTION Critical role in copper ### SEQUENCE -M-T-V-K-I-C-D-C-E-G-E-C-C-K-D-S-C-H-C-G-S-T-C-L-P-S-C-S-G-G-E-K-C-K-C-D-H-S-T-G-S-P-Q-C-K-S-C-G-E-K-C-K-C-E-T-T-C-T-C-E-K-S-K-C-N-C-E-K-C"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-S-Q-S-R-W-S-I-V-L-I-F-A-L-F-I-F-G-S-T-G-V-N-A-F-F-N-F-G-H-H-Q-Q-Q-Q-Q-Q-Q-Q-Q-S-Y-E-D-Q-V-L-N-N-P-C-D-G-Y-L-C-P-D-T-L-T-C-V-A-Q-Q-K-D-C-P-C-P-F-P-K-S-Q-L-K-C-V-L-P-D-N-K-F-V-C-I-S-K-P-A-T-H-N-E-K-F-R-A-I-Y-D-D-P-V-K-G-P-K-A-K-N-K-G-F-R-D-C-G-W-V-S-D-A-Y-K-N-H"} +{"text": "### FUNCTION Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions ### SEQUENCE -M-T-K-K-D-K-K-A-K-G-P-K-M-S-T-I-T-T-K-S-G-E-S-L-K-V-F-E-D-L-H-D-F-E-T-Y-L-K-G-E-T-E-D-Q-E-F-D-H-V-H-C-Q-L-K-Y-Y-P-P-F-V-L-H-D-A-H-D-D-P-E-K-I-K-E-T-A-N-S-H-S-K-K-F-V-R-H-L-H-Q-H-V-E-K-H-L-L-K-D-I-K-T-A-I-N-K-P-E-L-K-F-H-D-K-K-K-Q-E-S-F-D-R-I-V-W-N-Y-G-E-E-T-E-L-N-A-K-K-F-K-V-S-V-E-V-V-C-K-H-D-G-A-M-V-D-V-D-Y-K-T-E-P-L-Q-P-L-I"} +{"text": "### FUNCTION Stationary phase-essential protein not required for growth on nonfermentable carbon sources ### SEQUENCE -M-G-S-F-W-D-A-F-A-V-Y-D-K-K-K-H-A-D-P-S-V-Y-G-G-N-H-N-N-T-G-D-S-K-T-Q-V-M-F-S-K-E-Y-R-Q-P-R-T-H-Q-Q-E-N-L-Q-S-M-R-R-S-S-I-G-S-Q-D-S-S-D-V-E-D-V-K-E-G-R-L-P-A-E-V-E-I-P-K-N-V-D-I-S-N-M-S-Q-G-E-F-L-R-L-Y-E-S-L-R-R-G-E-P-D-N-K-V-N-R"} +{"text": "### FUNCTION Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions ### SEQUENCE -M-T-K-K-D-K-K-A-K-G-P-K-M-S-T-I-T-T-K-S-G-E-S-L-K-V-F-E-D-L-H-D-F-E-T-Y-L-K-G-E-T-E-D-Q-E-F-D-H-V-H-C-Q-L-K-Y-Y-P-P-F-V-L-H-D-A-H-D-D-P-E-K-I-K-E-T-A-N-S-H-S-K-K-F-V-R-H-L-H-Q-H-V-E-K-H-L-L-K-D-I-K-T-A-I-N-K-P-E-L-K-F-H-D-K-K-K-Q-E-S-F-D-R-I-V-W-N-Y-G-E-E-T-E-L-N-A-K-K-F-K-V-S-V-E-V-V-C-K-H-D-G-A-M-V-D-V-D-Y-R-T-E-P-L-Q-P-L-I"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-S-Q-S-R-W-S-I-V-L-I-F-A-L-F-I-F-G-S-T-G-V-N-A-F-F-N-F-G-H-H-Q-Q-Q-Q-Q-Q-Q-Q-Q-S-Y-E-D-Q-V-L-N-N-P-C-D-G-Y-L-C-P-D-T-L-T-C-V-A-Q-Q-K-D-C-P-C-P-F-P-K-S-Q-L-K-C-V-L-P-D-N-K-F-V-C-I-S-K-P-A-T-H-N-E-K-F-R-A-I-Y-D-D-P-V-K-G-P-K-A-K-N-K-G-F-R-D-C-G-W-V-S-D-A-Y-K-N-H"} +{"text": "### FUNCTION Stationary phase-essential protein not required for growth on nonfermentable carbon sources ### SEQUENCE -M-G-S-F-W-D-A-F-A-V-Y-D-K-K-K-H-A-D-P-S-V-Y-G-G-N-H-N-N-T-G-D-S-K-T-Q-V-M-F-S-K-E-Y-R-Q-P-R-T-H-Q-Q-E-N-L-Q-S-M-R-R-S-S-I-G-S-Q-D-S-S-D-V-E-D-V-K-E-G-R-L-P-A-E-V-E-I-P-K-N-V-D-I-S-N-M-S-Q-G-E-F-L-R-L-Y-E-S-L-R-R-G-E-P-D-N-K-V-N-R"} +{"text": "### FUNCTION Critical role in copper ### SEQUENCE -M-T-V-K-I-C-D-C-E-G-E-C-C-K-D-S-C-H-C-G-S-T-C-L-P-S-C-S-G-G-E-K-C-K-C-D-H-S-T-G-S-P-Q-C-K-S-C-G-E-K-C-K-C-E-T-T-C-T-C-E-K-S-K-C-N-C-E-K-C"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-R-A-L-T-S-L-S-V-V-L-L-A-L-I-S-T-V-S-A-Q-F-G-F-F-E-Q-M-F-G-G-Q-Q-Q-G-Q-Q-Q-R-P-Q-N-V-P-S-D-S-A-A-Y-R-Q-Q-Y-D-R-S-Y-C-E-H-Y-L-C-P-D-T-L-A-C-V-H-Y-P-H-H-C-P-C-P-W-P-M-N-E-D-K-F-E-L-S-E-G-Q-R-I-C-V-S-K-G-G-F-A-A-N-E-A-A-R-K-V-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Oxygen-regulated protein required for bacterial internalization ### SEQUENCE -M-I-R-R-N-R-Q-M-N-R-Q-P-L-P-I-I-W-Q-R-I-I-F-D-P-L-S-Y-I-H-P-Q-R-L-Q-I-A-P-E-M-I-V-R-P-A-A-R-A-A-A-N-E-L-I-L-A-A-W-R-L-K-N-G-E-K-E-C-I-Q-N-S-L-T-Q-L-W-L-R-Q-W-R-R-L-P-Q-V-A-Y-L-L-G-C-H-K-L-R-A-D-L-A-R-Q-G-A-L-L-G-L-P-D-W-A-Q-A-F-L-A-M-H-Q-G-T-S-L-S-V-C-N-K-A-P-N-H-R-F-L-L-S-V-G-Y-A-Q-L-N-A-L-N-E-F-L-P-E-S-L-A-Q-R-F-P-L-L-F-P-P-F-I-E-E-A-L-K-Q-D-A-V-E-M-S-I-L-L-L-A-L-Q-Y-A-Q-K-Y-P-N-T-V-P-A-F-A-C"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-D-S-F-D-A-P-D-R-Y-V-S-F-K-G-I-D-C-E-G-N-S-R-R-I-I-D-R-L-H-M-H-I-D-D-P-A-K-T-N-A-F-W-E-R-F-R-A-K-L-A-I-A-E-D-P-L-K-R-Q-A-D-G-L-C-L-L-C-A-N-I-Y-Y-I-A-D-L-F-E-E-H-D-D-E-D-G-L-A-M-L-R-Q-L-E-D-E-C-C"} +{"text": "### FUNCTION Makes mgtA transcription sensitive to intracellular proline levels Under low levels of proline this protein cannot be fully translated, and a stem loop forms which permits transcription of the downstream mgtA gene ### SEQUENCE -M-E-P-D-P-T-P-L-P-R-R-R-L-K-L-F-R"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-S-Q-A-A-V-K-I-D-R-Y-I-T-F-E-G-I-E-C-D-E-Q-A-R-R-V-L-D-C-I-R-D-C-I-E-A-P-E-A-S-S-W-S-A-Y-F-E-R-K-L-D-E-I-T-R-M-G-Q-D-E-L-F-V-V-G-S-Q-V-N-Y-I-R-A-L-F-E-H-H-G-H-R-E-G-L-D-L-L-D-R-I-E-D-E-C-C"} +{"text": "### FUNCTION Probable terminase small subunit The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit and a large terminase subunit Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine Once the capsid is packaged with the DNA, the terminase complex is substituted by the connector proteins gp15 ### SEQUENCE -M-Q-T-Q-K-G-G-R-P-T-I-L-P-K-M-Y-E-E-P-L-F-S-Q-I-I-D-K-I-E-S-G-C-N-D-R-E-I-Y-T-S-L-H-C-S-A-K-T-F-R-K-W-R-D-D-N-I-K-A-Y-D-E-A-K-S-I-A-R-G-N-L-L-E-L-A-E-S-A-L-A-S-K-L-T-V-R-T-L-K-E-T-E-T-I-Y-D-A-D-G-N-V-E-K-V-K-V-K-E-K-E-L-D-K-D-S-L-V-A-M-M-V-A-K-A-G-N-P-E-L-Y-N-P-T-E-W-R-R-L-Q-Q-E-E-S-S-A-H-D-L-K-A-K-I-E-E-L-D-D-Y-K-L-S-K-Y-K-T-P-E-I-E-V-P-E-G-F-E"} +{"text": "### FUNCTION Immunity protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition system Neutralizes the tRNase activity of cognate toxin WapA upon expression in Ecoli Does not inhibit WapA from other strains of Bsubtilis The WapA C-terminus cannot be expressed on its own in Ecoli, however it can be cloned in the presence of its cognate immunity protein gene Cell contact is probably necessary for growth inhibition ### SEQUENCE -M-K-F-F-K-R-Y-N-I-D-Q-K-T-L-D-E-F-K-K-Y-Y-V-L-L-H-G-P-F-P-N-D-M-Y-D-F-E-E-E-T-N-T-S-L-D-E-F-Y-E-F-F-A-L-I-T-G-S-L-N-Y-I-I-E-D-K-K-I-P-R-Y-Q-R-E-M-L-K-K-T-F-Y-E-H-Y-P-H-F-R-N-Y-K-S-D-I-L-K-Y-Q-E-L-S-E-C-L-E-F-H-E-K-I-R-I-L-I-N-K-L-I-T-G-G"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-C-N-C-K-K-N-I-K-V-D-E-S-Y-V-S-F-K-D-I-D-C-F-E-N-A-C-L-V-I-D-N-L-L-R-I-L-K-E-P-K-N-T-N-A-Y-W-E-K-F-I-E-K-I-P-E-A-Y-Y-T-R-D-S-K-K-D-P-S-E-A-L-L-Y-L-V-C-S-C-T-S-N-I-M-E-L-F-E-E-I-D-D-E-E-A-I-D-A-M-S-K-C-E-Q-E-C-C"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-N-D-Q-T-P-D-R-Y-V-T-F-M-G-I-A-C-D-T-N-A-D-R-L-C-E-M-L-A-A-R-M-A-G-N-D-S-R-W-V-A-Y-F-E-K-K-L-A-E-N-A-Q-M-G-H-D-R-L-R-F-I-G-A-Q-V-N-A-L-M-S-F-F-E-E-E-D-D-E-A-A-L-A-L-L-W-H-I-E-H-H-C-L"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-S-N-F-E-I-R-V-N-E-S-Y-E-S-F-K-N-I-D-C-F-E-N-A-C-V-V-I-D-N-M-L-R-V-L-E-N-P-K-N-M-N-I-Y-W-K-K-I-V-P-M-I-P-K-A-Y-Y-D-R-D-P-K-S-D-T-K-E-E-L-L-Y-L-V-C-S-N-S-F-Y-L-D-E-L-F-E-K-A-E-D-E-Q-A-I-N-A-L-S-K-C-E-Q-E-C-C"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-S-R-S-S-L-L-L-V-F-F-T-L-F-G-L-A-A-A-Q-F-Q-F-F-N-D-F-F-G-G-Q-Q-H-H-Q-Q-Q-Q-R-T-G-A-S-Q-Y-A-A-F-S-E-N-V-P-C-S-H-Y-L-C-P-G-T-M-D-C-V-E-R-P-R-D-C-P-C-P-D-V-Q-D-V-K-C-L-I-P-D-M-D-S-D-D-D-E-A-T-V-V-C-V-R-G-G-T-D-C-S-T-V-E-K-L-M-K-R-G-S"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-S-E-Q-I-D-R-Y-V-S-F-K-N-I-D-C-N-A-R-A-G-Q-M-M-D-A-L-Q-P-Y-I-Q-A-A-E-N-P-F-W-A-Y-F-Q-Q-K-R-A-E-F-N-A-K-G-Y-D-D-L-R-V-L-H-N-Y-L-P-T-L-K-E-L-I-E-D-D-E-L-L-A-Q-L-E-D-L-E-Y-T-C-M"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-R-F-F-A-S-L-P-L-V-I-L-A-L-I-S-S-A-Q-A-Q-F-G-F-F-D-Q-M-F-G-G-Q-Q-Q-Q-Q-Q-Q-P-Q-N-V-P-S-D-P-S-Q-Y-Q-Q-R-Y-D-G-S-Y-C-E-N-Y-L-C-P-D-T-L-A-C-V-H-F-P-H-H-C-P-C-P-W-P-A-N-Q-D-K-F-E-L-T-E-G-S-S-R-I-C-V-S-K-G-G-F-A-A-G-E-A-A-R-K-V-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-A-S-I-L-R-T-A-L-L-G-L-L-L-F-T-T-A-Q-A-Q-F-Q-F-F-E-Q-M-F-G-G-G-Q-Q-H-Q-E-S-S-G-Q-G-G-N-V-P-S-D-S-A-W-Y-Q-N-T-Y-N-G-A-Q-C-S-N-Y-L-C-P-G-T-L-A-C-V-A-V-P-H-H-C-P-C-A-H-P-K-V-E-E-K-F-E-L-G-E-G-S-A-I-C-A-S-K-G-G-F-K-A-G-E-T-A-R-K-I-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-A-R-P-Y-M-I-F-A-V-L-T-A-W-F-F-G-C-N-A-Q-F-G-F-F-D-Q-M-F-G-G-G-G-G-G-G-Q-Q-Q-Q-Q-P-Q-N-V-R-S-D-S-V-W-Y-Q-Q-Q-Y-E-A-A-Q-C-S-H-Y-L-C-P-G-T-L-S-C-V-H-F-P-H-H-C-P-C-A-W-E-G-V-E-E-K-I-E-L-G-E-G-I-A-I-C-A-S-K-G-G-W-A-E-G-E-F-A-K-K-V-E-L-A-R-K-G-M-L"} +{"text": "### FUNCTION Required for efficient viral DNA synthesis and the late accumulation of viral IE transcripts ### SEQUENCE -M-G-G-S-P-V-P-Q-L-T-T-V-T-Q-G-L-M-P-S-V-R-M-D-F-R-A-R-R-P-L-R-R-L-A-F-Y-A-P-R-A-R-R-R-L-F-Q-N-H-I-H-P-E-Q-R-R-V-L-V-G-E-G-D-E-E-M-L-P-D-L-P-M-E-I-D-I-V-I-D-R-P-P-Q-Q-P-L-P-N-P-L-V-L-L-L-D-D-V-P-P-H-V-P-G-F-A-P-Y-R-V-P-R-P-H-P-M-I-P-E-E-H-W-D-Q-F"} +{"text": "### FUNCTION May stimulate membrane curvature formation and subsequent endoplasmic reticulum exit site establishment ### SEQUENCE -M-S-N-Q-G-K-D-S-F-K-A-Y-S-Y-F-C-P-C-G-Q-L-F-L-T-I-H-V-S-L-T-R-L-P-Q-R-Q-L-D-K-R-H-V-V-D-E-K-L-N-H-I-A-H-F-S-T-G-N-K-Y-Y-I-T-R-S-D-G-G-Y-E-Q-R-I-Q-L-L-C-R-R-C-T-L-E-C-A-Y-A-L-E-A-A-P-G-Y-I-Y-V-D-P-T-L-V-N-E-K-P-V-T-V-S-V-S-N-L-K-E"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system Its cognate toxin is VapC51 ### SEQUENCE -M-A-K-H-L-V-D-I-D-E-Q-A-L-N-M-A-R-T-E-L-G-T-T-T-I-K-D-T-V-N-A-A-L-R-Q-A-T-S-Q-R-V-Q-R-V-A-A-A-L-D-T-L-A-A-A-P-P-E-D-R-A-E-A-W-R"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system An RNase The cognate antitoxin is VapB50 ### SEQUENCE -M-P-C-C-G-S-L-T-R-A-P-I-G-L-C-G-R-R-T-S-W-P-R-L-G-E-P-W-S-T-A-S-T-S-A-P-N-G-L-T-T-A-F-A-F-G-Y-N-D-L-I-A-A-M-N-N-H-Y-K-D-R-H-V-L-A-A-A-V-R-E-R-A-E-V-I-V-T-T-N-L-K-H-F-P-D-D-A-L-K-P-Y-Q-I-K-A-L-H-P-D-D-F-L-L-D-Q-L-D-L-Y-E-E-A-T-K-A-V-I-L-G-M-V-D-A-Y-I-D-P-P-F-T-P-H-S-L-L-D-A-L-G-E-Q-V-P-Q-F-A-A-K-A-R-R-L-F-P-S-G-S-P-F-G-L-G-V-L-L-P-F-D-Q"} +{"text": "### FUNCTION Protects linear double-stranded DNA of Mu genome from exonuclease degradation ### SEQUENCE -M-A-T-K-V-K-S-Q-A-K-L-R-F-V-S-V-E-Q-V-Q-S-A-I-K-E-I-G-D-L-S-R-E-H-T-R-L-A-T-E-M-N-D-K-I-G-A-T-S-E-H-Y-A-P-K-L-K-A-L-K-E-E-I-E-P-L-Q-K-A-V-Q-E-Y-C-E-A-N-R-D-E-L-T-E-F-G-K-T-K-T-A-N-F-V-T-G-E-V-Q-W-R-Q-R-P-P-S-V-A-I-R-G-A-E-A-V-M-E-F-L-Q-R-M-G-F-D-R-F-I-R-T-R-Q-E-I-N-K-E-A-L-L-N-E-P-E-V-A-K-G-I-A-G-V-T-I-K-Q-G-L-E-D-F-V-I-K-P-F-E-Q-D-A-R"} +{"text": "### FUNCTION Might take part in the signal recognition particle ### SEQUENCE -M-K-L-K-N-N-L-L-E-K-T-L-E-L-S-E-L-F-K-I-Y-K-E-L-L-T-D-K-Q-K-Q-Y-F-E-L-Y-I-D-E-D-L-S-L-S-E-I-A-D-E-F-N-I-S-K-T-A-V-Y-D-S-I-S-K-T-S-K-L-L-F-S-L-E-T-K-L-H-L-K-Q-K-Q-D-L-L-I-S-L-I-N-K-I-E-T-N-Q-I-D-E-K-Q-F-I-K-S-L-K-E-V-I-W-W-K-Y"} +{"text": "### FUNCTION Antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC8 ### SEQUENCE -M-E-K-S-R-C-H-A-V-A-H-G-G-G-C-A-G-S-A-K-S-H-K-S-G-G-R-C-G-Q-G-R-G-A-G-D-S-H-G-T-R-G-A-G-R-R-Y-R-A-A-S-A-P-H-P-L-A-V-G-A-H-L-R-D-E-L-A-K-R-S-A-D-P-R-L-T-D-E-L-N-D-L-A-G-H-T-L-D-D-L"} +{"text": "### FUNCTION Antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC7 ### SEQUENCE -M-S-M-R-L-A-H-R-L-Q-I-L-L-D-D-E-C-H-R-R-I-T-A-V-A-R-E-R-G-V-P-V-A-T-V-V-R-E-A-I-D-R-G-L-V-S-P-A-G-R-R-K-S-A-G-R-R-L-L-D-A-A-D-M-S-V-P-E-P-R-E-L-K-Q-E-L-E-A-L-R-A-R-R-G"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-L-S-F-R-A-D-D-H-D-V-D-L-A-D-A-W-A-R-R-L-H-I-G-R-S-E-L-L-R-D-A-L-R-R-H-L-A-A-L-A-A-D-Q-D-V-Q-A-Y-T-E-R-P-L-T-D-D-E-N-A-L-A-E-I-A-D-W-G-P-A-E-D-W-A-D-W-A-D-A-A-R"} +{"text": "### FUNCTION This protein is required for viral late gene expression ### SEQUENCE -M-E-T-A-Q-P-P-I-S-Y-A-P-P-K-R-G-A-V-C-A-Y-V-R-T-V-V-T-T-T-T-V-S-D-S-G-G-N-N-E-D-R-L-T-Q-I-V-A-Q-L-Q-R-T-R-L-N-F-S-K-L-S-Q-L-Q-R-R-R-V-R-N-M-Q-K-L-I-R-K-K-N-S-V-I-A-N-L-A-A-R-L-T-T-Q-K-K-T-K-H-F-A-V-T-I-R-K-N-V-I-H-T-T-S-G-S-E-Q-F-V-R-Q-R-V-L-E-L-C-A-N-G-G-E-Q-V-F-C-A-R-R-A-D-C-A-R-D-R-R-R-V-A-E-A-L-A-T-A-L-G-A-G-V-V-A-S-A-A-N-K-R-F-E-I-E-D-E-E-K-L-V-S-A-K-L-I-V-Q-Q-V-L-H-D-G-D-H-S-D-T-C-A-D"} +{"text": "### FUNCTION Involved in late/very late gene activation ### SEQUENCE -M-T-H-V-L-S-A-A-A-N-D-L-I-A-C-V-L-R-D-N-L-F-S-A-D-G-E-C-L-R-Y-V-V-C-K-E-A-G-H-V-E-S-V-Y-I-G-E-I-G-A-A-Q-A-H-S-G-D-Q-N-A-V-L-D-A-S-S-A-S-D-V-S-S-S-A-S-S-R-R-V-S"} +{"text": "### FUNCTION Is able to bind two actin monomers at high concentrations of G-actin ### SEQUENCE -D-A-K-A-L-A-G-I-A-D-A-K-L-K-H-T-E-T-G-D-K-S-A-P-V-I-E-N-V-E-I-K-K-G-D-R-N-E-L-L-S-G-I-K-E-G-K-E-L-K-K-A-E-T-N-D-R-S-A-P-V-I-P-A-D-A-K-V-Q-E-D-N-R-G-A-L-L-A-D-I-Q-A-T-A-K"} +{"text": "### FUNCTION Probable terminase small subunit The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit and a large terminase subunit Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine Once the capsid is packaged with the DNA, the terminase complex is substituted by the connector proteins gp15 ### SEQUENCE -M-Q-T-Q-K-G-G-R-P-T-I-L-P-K-M-Y-E-E-P-L-F-S-Q-I-I-D-K-I-E-S-G-C-N-D-R-E-I-Y-T-S-L-H-C-S-A-K-T-F-R-K-W-R-D-D-N-I-K-A-Y-D-E-A-K-G-I-A-R-G-N-L-L-E-L-A-E-S-A-L-A-S-K-L-T-V-R-T-L-K-E-T-E-T-I-Y-D-A-D-G-N-V-E-K-V-K-V-K-E-K-E-L-D-K-D-S-L-V-A-M-M-V-A-K-A-G-N-P-E-L-Y-N-P-T-E-W-R-R-L-Q-Q-E-E-S-S-A-H-D-L-K-A-K-I-E-E-L-D-D-Y-K-L-S-K-Y-K-T-P-E-I-E-V-P-E-G-F-E"} +{"text": "### FUNCTION Involved in the sensitivity of the virus to the host AbiV system ### SEQUENCE -M-N-Y-G-T-N-N-H-Y-A-N-E-Y-G-M-E-L-N-E-Y-F-K-H-H-F-N-Y-E-E-L-A-G-W-Y-T-M-Q-V-L-K-Y-L-V-R-A-G-K-K-E-G-E-S-Y-D-K-D-R-N-K-A-L-D-Y-A-G-E-L-A-N-L-S-N-E-N-E-L-T-E-Y-T-T-D-D-I-M-G-F-A-Q-D-I-A-D-D-F-K-Q-W-K-D-E-R-N-N-F-K-S-E-F-T-K-E-E-I-K-A-I-D-E-R-Y-L-E-F-I-E-E-V"} +{"text": "### FUNCTION Chaperone involved in tail fiber assembly ### SEQUENCE -M-S-R-T-L-D-L-I-L-L-C-R-L-V-Q-D-T-A-H-L-L-M-R-I-T-L-Q-W-D-I-N-E-M-S-Y-F-Y-S-A-S-T-N-G-F-Y-S-T-E-F-H-G-T-N-I-P-D-D-A-V-E-I-S-E-S-E-W-E-T-L-I-N-S-Q-G-V-T-K-M-I-T-C-G-E-N-G-H-P-V-I-V-D-R-P-S-P-T-P-E-R-L-A-L-I-N-D-E-K-K-S-A-L-I-A-E-A-T-N-V-I-A-P-L-Q-D-A-V-D-L-G-M-A-T-D-D-E-T-K-L-L-L-A-W-E-K-Y-R-V-L-L-M-R-V-D-I-K-N-T-E-W-P-K-K-P-E-G-N-K"} +{"text": "### FUNCTION Excisionase and integrase are necessary for the excision of prophage from the host genome by site-specific recombination ### SEQUENCE -M-H-G-M-G-Y-D-S-R-L-D-R-L-A-A-T-S-W-Y-P-F-F-N-N-V-T-A-R-G-E-I-M-E-P-Y-S-L-T-L-D-E-A-C-D-F-L-K-I-S-R-P-T-A-I-N-W-I-R-T-G-R-L-Q-A-T-R-K-D-P-T-K-S-K-S-P-Y-L-T-T-R-Q-A-C-I-A-A-L-Q-S-P-L-H-T-V-Q-V-S-A-G-D-G-I-T-E-E-R-K-C-H-S-S-A-E-V-K-Y-G-T-P-V-S-H-C-R-T-V-K-D-L-N-S-L-L-E-Q-R-T-K-G-R-R-Q-N-S-M-T-S"} +{"text": "### FUNCTION Modulates the action of auxin, and may function as plant growth regulator that alters phytohormone responses ### SEQUENCE -M-R-F-C-W-Q-K-S-I-H-G-S"} +{"text": "### FUNCTION Modulates the action of auxin, and may function as plant growth regulator that alters phytohormone responses ### SEQUENCE -M-K-L-C-W-Q-K-S-I-H-G-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-N-N-K-T-P-F-L-S-A-I-F-T-A-S-I-R-G-Y-Q-R-F-F-S-A-F-T-P-S-S-C-R-F-Y-P-T-C-S-N-Y-A-L-W-L-L-C-F-E-S-P-L-S-A-M-G-K-I-A-I-R-I-L-S-C-N-P-F-C-S-G-G-I-A-Y-P-T-T-R-L-K-R-P-S-L-I-Q-S-H-K-D-S-N-R-N-F-K-T-I-T-F-W-L-V-P-T-K-S-H-A-T-Y-Y-I-I-K-V"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-L-L-T-T-S-R-K-P-S-Q-R-T-R-S-F-S-Q-R-L-S-R-I-M-G-W-R-Y-I-N-R-G-K-M-S-L-R-D-V-L-I-E-A-R-G-P-V-A-V-V-S-E-R-H-G-N-P-A-R-I-T-F-L-D-E-R-G-G-E-R-G-Y-I-L-F-N-P-S-F-E-M-K-K-P-E-L-A-D-K-A-V-R-V-S-S-C-P-P-G-S-E-G-L-C-N-L-M-G-L-E-V-D-E-S-S-S-R-D-A-W-S-I-R-T-D-E-E-Y-A-W-V-M-E-L-M-D-A-R-G-T-P-A-G-F-K-L-L-I-R-D-F-R-V-G-E"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-P-K-I-I-E-A-V-Y-E-N-G-V-F-K-P-L-Q-K-V-D-L-K-E-G-E-R-V-K-I-K-L-E-L-K-V-E-P-I-D-L-G-E-P-V-S-V-E-E-I-K-K-I-R-D-G-T-W-M-S-S"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-T-K-T-I-S-I-S-D-D-V-Y-E-M-L-V-K-I-K-G-K-R-S-F-S-E-V-I-R-E-L-V-K-K-E-G-N-F-D-L-L-M-V-A-F-G-T-R-S-E-E-E-V-E-K-L-K-R-E-M-K-E-V-E-E-W-M-Q-S-L-C-N-H"} +{"text": "### FUNCTION Involved in resistance toward heavy metals ### SEQUENCE -M-H-N-F-I-Y-I-T-A-P-S-L-E-E-A-E-R-I-A-K-R-L-L-E-K-K-L-A-A-C-V-N-I-F-P-I-K-S-F-F-W-W-E-G-K-I-E-A-A-T-E-F-A-M-I-V-K-T-R-S-E-K-F-A-E-V-R-D-E-V-K-A-M-H-S-Y-T-T-P-C-I-C-A-I-P-I-E-R-G-L-K-E-F-L-D-W-I-D-E-T-V-E"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-G-E-I-I-E-A-V-Y-Q-K-G-V-L-K-P-L-R-K-V-S-L-R-E-G-E-I-V-K-V-E-I-R-E-T-K-K-V-T-G-R-F-Y-A-K-L-R-E-L-E-K-R-I-E-R-V-E-G-A-H-R-E-L-E-E-I-R-D-D-R-Y"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-K-N-I-M-V-R-D-E-V-Y-E-K-L-Q-K-M-K-K-G-R-E-S-F-S-D-V-I-L-R-L-I-E-G-R-K-K-R-G-I-E-I-L-E-R-Y-A-G-S-L-S-D-S-E-L-E-K-I-V-M-E-E-R-R-K-F-R-V-R-S-F-D-S"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-K-T-I-S-I-R-D-D-V-Y-R-K-L-L-E-M-K-D-E-E-D-S-F-S-D-V-I-E-K-L-L-K-R-K-K-T-D-I-R-R-Y-F-G-V-L-K-D-S-E-V-L-D-E-I-E-K-S-L-N-A-R-K-S-A-R-F-R-V"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-P-T-K-T-I-T-I-T-L-E-A-Y-E-R-L-K-R-E-K-R-E-G-E-S-F-S-D-V-I-I-R-L-T-E-K-R-R-D-L-L-E-F-A-G-K-W-K-D-S-G-E-E-I-E-K-I-I-L-E-G-R-K-E-F-D-K-H-V-L-S"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-Q-V-L-T-T-S-R-K-P-G-R-K-T-R-R-F-A-K-V-L-A-R-F-F-N-W-K-Y-V-N-R-G-K-L-S-L-E-D-L-A-G-I-A-E-R-F-W-I-I-S-E-V-K-G-N-P-A-I-L-N-L-Y-E-R-G-E-K-T-L-E-V-S-F-T-L-S-N-V-N-K-I-K-M-D-D-S-P-A-V-F-K-G-K-A-P-I-D-P-L-V-F-G-A-I-P-Q-T-K-A-G-L-K-L-T-R-K-V-E-F-R-K-K-V-V-V-K-G-D-E-W-L-F-F-Y-D-D-E-M-L-F-K-L-R-I-L-K-I-S-R-S-S-R"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-P-K-I-I-E-A-I-Y-E-N-G-V-F-K-P-L-Q-K-V-D-L-K-E-G-E-R-I-K-L-R-I-E-E-G-I-L-D-V-I-K-K-Y-Q-G-K-F-K-L-T-E-K-D-I-E-K-F-L-E-E-R-R"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-P-K-I-I-E-A-I-Y-E-N-G-V-F-K-P-L-Q-K-V-D-L-K-E-G-E-R-V-R-V-V-V-S-E-V-V-A-K-T-R-G-L-L-K-G-C-E-M-E-E-I-I-E-E-I-E-S-E-G-F-L"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-P-K-I-I-E-A-V-Y-E-N-G-V-F-K-P-L-Q-K-V-D-L-R-E-G-E-K-V-K-I-I-A-G-N-L-V-E-R-L-R-K-Y-R-V-K-V-D-S-D-I-V-A-E-F-I-S-E-R-R"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-P-K-I-I-E-A-V-Y-E-N-G-V-F-K-P-L-Q-K-V-D-L-K-E-G-E-K-I-R-L-R-I-E-E-G-I-A-D-V-I-K-E-F-S-R-K-V-D-Q-D-V-L-E-E-F-L-R-E-R-R"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-P-K-I-I-E-A-I-Y-E-N-G-V-F-K-P-L-Q-K-V-D-L-K-E-G-E-K-I-R-I-L-L-K-K-I-D-V-E-K-F-I-M-A-K-L-P-E-E-K-I-R-E-L-E-R-R-F-E-D-E-N-L-Y"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-P-K-I-I-E-A-V-Y-E-N-G-V-F-K-P-L-Q-K-V-D-L-R-E-G-E-R-E"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-P-K-I-I-E-A-I-Y-E-N-G-V-F-K-P-L-Q-K-V-D-L-K-E-G-E-R-V-R-I-K-L-E-K-V-E-E-V-V-D-E-V-F-G-I-L-K-G-K-D-T-L-K-A-L-R-E-L-E-E-W-G-F-C"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-P-K-V-I-E-A-V-Y-E-N-G-V-F-K-P-L-Q-K-V-D-L-K-E-G-E-K-V-K-V-E-L-K-E-S-V-V-E-S-V-A-G-I-L-K-V-S-D-E-K-V-K-K-A-L-E-M-I-E-Y-G-E-D-I-Y"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-P-K-I-I-E-A-I-Y-E-N-G-V-F-K-P-L-Q-K-V-N-F-R-P-G-S-K-V-R-I-V-I-Q-E-D-K-K-E-I-L-R-K-Y-K-G-V-F-G-K-A-E-V-E-E-L-R-E-Y-E-G-E-V-M-L"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-P-K-I-I-E-A-I-Y-E-N-G-V-F-K-P-L-Q-K-V-D-L-K-E-G-E-K-A-K-I-V-L-E-S-I-S-D-K-T-F-G-I-L-K-A-S-E-T-E-I-K-K-V-L-E-E-I-D-D-F-W-G-V-C"} +{"text": "### FUNCTION Required for translation of SpoIIID ### SEQUENCE -M-G-I-F-H-K-L-T-F-K-T-I-Q-R-R-S-G-I-M-N-D-S-L-Q-N-T-D-L-I-S-H-F-S-H-P-F"} +{"text": "### FUNCTION May be involved in the regulation of muramidase export ### SEQUENCE -M-L-L-P-E-I-D-E-K-A-T-V-K-R-C-K-R-K-L-R-E-Y-P-R-W-R-E-I-A-H-D-S-A-E-Q-K-I-T-Q-E-F-T-F-M-P-R-G-G-S-G-V-N-K-P-V-E-N-I-A-V-R-R-V-D-A-L-S-E-L-E-A-I-E-Q-A-V-N-G-L-Y-R-P-D-Y-R-R-I-L-I-E-K-Y-L-A-Y-P-P-Q-P-N-W-K-I-A-Q-A-I-G-F-E-R-T-A-F-Q-E-L-L-K-H-S-I-L-A-F-A-E-L-Y-R-N-G-Q-L-V-V-E-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-L-F-I-A-L-I-R-G-Y-Q-K-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-Q-Y-G-I-E-A-I-K-T-H-G-A-L-K-G-G-W-L-T-I-K-R-I-L-K-C-H-P-F-H-P-G-G-V-D-P-V-P-E-K-K-Q-K-H"} +{"text": "### FUNCTION Mediates the regulatory switch from transcription to RNA replication Acts late in infection by inhibiting viral transcription and up-regulating RNA replication Inhibition of transcription by protein M2-2 requires phosphorylation of the phosphoprotein ### SEQUENCE -M-T-K-P-K-I-M-I-L-P-D-K-Y-P-C-S-I-S-S-I-L-I-S-S-E-S-M-I-A-T-F-N-H-K-N-I-L-Q-F-N-H-N-H-L-D-N-H-Q-R-L-L-N-N-I-F-D-E-I-H-W-T-P-K-N-L-L-D-A-T-Q-Q-F-L-Q-H-L-N-I-P-E-D-I-Y-T-I-Y-I-L-V-S"} +{"text": "### FUNCTION Positively regulates expression of some phage genes Bacterial host RNA polymerase modified by antitermination proteins transcribes through termination sites that otherwise prevent expression of the regulated genes ### SEQUENCE -M-R-D-I-R-Q-V-L-E-R-W-G-A-W-A-A-N-N-H-E-D-V-T-W-S-P-I-A-A-G-F-K-G-L-I-P-E-K-V-K-S-R-P-Q-C-C-D-D-D-A-M-I-I-C-G-C-M-A-R-L-N-R-N-N-S-D-L-H-D-L-L-V-D-Y-Y-V-L-G-E-T-F-M-A-L-A-R-K-H-G-C-S-D-T-C-I-G-K-R-L-H-K-A-E-G-I-V-E-G-M-L-M-M-L-G-V-R-L-E-M-D-R-Y-V-E-R-E-L-P-G-G-R-T-S-V-F-Y-Q-R-K-N-S-L-R-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-R-F-V-I-Q-L-I-Q-L-Y-K-R-L-L-S-P-L-L-P-P-A-C-R-F-T-P-T-C-S-E-Y-A-A-Q-A-F-Q-E-Y-G-F-F-R-A-L-Q-L-S-I-W-R-I-L-R-C-N-P-L-S-R-G-F-D-D-P-L-P-P-N-T-K-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-I-F-K-I-L-F-I-L-N-Y-A-L-I-F-L-I-K-I-Y-Q-N-T-L-S-K-I-F-G-L-Q-C-I-Y-K-P-T-C-S-K-Y-S-I-E-C-L-K-K-Y-N-F-L-T-A-L-I-L-M-T-L-R-I-I-R-C-N-A-L-F-K-G-G-N-D-F-T-P-K-Y-K-P-I-L-E-S-L-K-E-F-K-K-R-L-I-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-D-I-T-D-I-R-I-K-K-V-D-S-K-N-S-G-S-K-L-L-A-Y-V-A-V-T-F-D-N-C-L-V-L-H-N-I-R-V-I-K-G-Q-K-G-V-F-I-A-M-P-N-R-R-T-R-V-G-E-Y-K-D-I-V-H-P-I-S-Q-D-F-R-K-A-L-Q-T-S-I-F-K-E-Y-I-R-E-N-P-A-D-L-E-L-E-L-D-F"} +{"text": "### FUNCTION Probable antitoxin component of a type II toxin-antitoxin system Neutralizes the activity of cognate toxin Rv3189 by blocking access to the toxin active site ### SEQUENCE -M-A-V-T-L-D-R-A-V-E-A-S-E-I-V-D-A-L-K-P-F-G-V-T-Q-V-D-V-A-A-V-I-Q-V-S-D-R-A-V-R-G-W-R-T-G-D-I-R-P-E-R-Y-D-R-L-A-Q-L-R-D-L-V-L-L-L-S-D-S-L-T-P-R-G-V-G-Q-W-L-H-A-K-N-R-L-L-D-G-Q-R-P-V-D-L-L-A-K-D-R-Y-E-D-V-R-S-A-A-E-S-F-I-D-G-A-Y-V"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system An RNase The cognate antitoxin is VapB45 ### SEQUENCE -M-Q-P-D-R-N-L-L-A-D-L-D-H-I-F-V-D-R-S-L-G-A-V-Q-V-P-Q-L-L-R-D-A-G-F-R-L-T-T-M-R-E-H-Y-G-E-T-Q-A-Q-S-V-S-D-H-K-W-I-A-M-T-A-E-C-G-W-I-G-F-H-K-D-A-N-I-R-R-N-A-V-E-R-R-T-V-L-D-T-G-A-R-L-F-C-V-P-R-A-D-I-L-A-E-Q-V-A-A-R-Y-I-A-S-L-A-A-I-A-R-A-A-R-F-P-G-P-F-I-Y-T-V-H-P-S-K-I-V-R-V-L"} +{"text": "### FUNCTION More likely to influence phosphoinositide metabolism than actin assembly ### SEQUENCE -M-A-E-W-H-K-I-I-E-D-I-S-K-N-N-K-F-E-D-A-A-I-V-D-Y-K-T-T-K-N-V-L-A-A-I-P-N-R-T-F-A-K-I-N-P-L-I-T-N-R-N-I-L-K-P-L-I-G-Q-K-Y-C-I-V-Y-T-N-S-L-M-D-E-N-T-Y-A-M-E-L-L-T-G-Y-A-P-V-S-P-I-V-I-A-R-T-H-T-A-L-I-F-L-M-G-K-P-T-T-S-R-R-D-V-Y-R-T-C-R-D-H-A-T-R-V-R-A-T-G-N"} +{"text": "### FUNCTION May be involved in the secretion of the autolysin blyA ### SEQUENCE -M-E-M-D-I-T-Q-Y-L-S-T-Q-G-P-F-A-V-L-F-C-W-L-L-F-Y-V-M-K-T-S-K-E-R-E-S-K-L-Y-N-Q-I-D-S-Q-N-E-V-L-G-K-F-S-E-K-Y-D-V-V-I-E-K-L-D-K-I-E-Q-N-F-K"} +{"text": "### FUNCTION Putative excisionase ### SEQUENCE -M-K-I-L-S-R-D-K-V-A-L-K-V-A-T-A-G-T-V-A-V-G-G-L-A-F-S-L-S-F-T-A-L-S-E-L-S-A-A-N-G-V-A-Q-S-W-M-V-P-L-V-I-D-G-G-I-L-V-A-T-M-A-T-V-A-L-S-R-H-G-W-Y-A-W-A-L-L-I-L-S-S-L-M-S-V-A-G-N-V-A-H-A-Q-P-H-G-L-I-A-M-V-I-A-A-I-P-P-L-W-L-L-A-S-T-H-L-T-V-L-L-Y-R-E-A-Q-E-S-G-S-E-S-I-S-E-P-L-L-T-R-G-F-A-E-A-A"} +{"text": "### FUNCTION Putative decoration protein ### SEQUENCE -M-A-I-T-E-V-F-T-H-K-Q-P-L-G-N-S-D-P-A-H-T-A-Y-G-P-G-E-L-T-A-S-T-P-A-M-T-P-L-M-L-D-A-T-S-G-K-L-T-V-W-D-G-A-H-A-G-A-A-T-G-I-L-A-V-T-A-D-Q-N-S-A-E-L-A-F-Y-K-S-G-S-F-R-I-E-D-V-L-W-P-S-A-V-T-D-E-N-I-K-R-N-A-F-A-G-T-A-I-S-I-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-S-I-V-L-I-F-L-K-F-W-Q-K-F-I-S-P-L-Y-P-S-S-C-R-Y-Y-P-T-C-S-T-Y-A-I-M-A-V-E-K-Y-G-V-L-K-G-L-I-K-A-F-F-R-V-L-R-C-N-P-F-F-K-G-G-V-D-Y-P"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-L-V-V-Y-S-S-S-V-T-D-N-T-H-R-F-V-Q-K-L-D-L-P-N-V-R-I-P-L-R-L-K-D-E-P-L-I-V-N-E-P-Y-V-L-V-C-P-T-Y-G-G-G-V-S-L-T-G-E-N-S-R-P-V-P-R-Q-V-I-R-F-L-N-N-E-H-N-R-S-F-I-R-A-V-V-A-G-G-N-S-N-F-G-A-D-F-G-K-A-G-E-V-I-S-A-K-C-K-V-P-Y-V-Y-R-F-E-M-M-G-N-E-D-D-V-R-I-C-R-G-G-L-V-Q-N-A-A-K-L-G-L-E-K-Q-A-S"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system Its cognate toxin is VapC50 ### SEQUENCE -M-T-S-L-L-E-V-L-G-A-P-E-V-S-V-C-G-N-A-G-Q-P-M-T-L-P-E-P-V-R-D-A-L-Y-N-V-V-L-A-L-S-Q-G-K-G-I-S-L-V-P-R-H-L-K-L-T-T-Q-E-A-A-D-L-L-N-I-S-R-P-T-L-V-R-L-L-E-D-G-R-I-P-F-E-K-P-G-R-H-R-R-V-S-L-D-A-L-L-E-Y-Q-Q-E-T-R-S-N-R-R-A-A-L-G-E-L-S-R-D-A-L-G-E-L-Q-A-A-L-A-E-K-K"} +{"text": "### FUNCTION Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier ### SEQUENCE -M-S-Y-R-F-L-T-V-R-A-F-G-F-T-G-F-H-C-D-A-T-R-L-L-S-E-T-E-V-I-D-V-P-S-S-L-D-F-V-G-E-T-E-L-R-L-E-T-A-W-P-Q-C-E-E-N-C-Y-T-I-L-P-R-F-N-V-Q-V-D-F-E-Y-Y-P-V-R-V-E-I-V-C-R-V-C-A-A-S-L-S-V-I-F-S-K-W-D-F-Y-C-S-R-R-G-H-F-V-P-V-D-Q-N-G-D-L-F-R-I-G-T-L-Q-E-T-G-E-K-Y-F-Y-F-C-D-K-S-I-C-R-Q-C-I-I-Q-A-A-H-H-H-S"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-S-K-T-I-T-I-A-D-D-V-Y-Y-E-L-V-K-M-K-G-K-R-S-F-S-E-V-L-R-E-L-I-G-K-K-K-E-G-N-L-D-V-L-M-I-A-F-G-T-M-D-E-E-E-A-K-E-L-E-E-K-I-K-E-V-G-K-W-L-N-S-W-T-P-V"} +{"text": "### FUNCTION May play a role in the structure of the hypha-forming fruit bodies ### SEQUENCE -M-S-F-K-T-R-A-V-A-E-S-T-Y-Y-I-K-S-G-A-Y-Y-L-A-V-T-P-E-R-Q-I-I-T-Q-N-T-V-Y-A-W-E-V-S-I-E-G-E-Y-N-Y-L-K-D-P-G-T-T-H-Y-L-T-D-N-G-G-Q-N-L-L-N-P-R-S-D-V-D-G-K-W-G-G-G-S-E-D-Q-A-T-Q-L-I-N-A-E-T-E-K-P-L-S-V-P-Y-G-Q-P-F-Q-T-W-L-F-V-K-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-S-R-I-S-S-F-F-R-G-L-V-H-L-Y-R-W-A-I-S-P-F-L-G-A-P-C-R-F-F-P-T-C-S-E-Y-A-L-V-A-L-K-K-H-P-L-R-K-S-L-F-L-I-A-K-R-L-L-K-C-G-P-W-C-I-G-G-I-D-L-V-P-R-T-S-V-E-E-Y-L-S-S-P-T-P-L-A-E-S-P-D-D-R-T-V-P-H-T-Q-E-T-S"} +{"text": "### FUNCTION Involved in late/very late gene activation ### SEQUENCE -M-P-P-K-N-C-T-H-L-G-G-C-N-S-D-C-L-T-R-S-E-I-Q-A-L-F-R-E-A-I-N-T-L-K-H-T-M-N-T-E-D-V-C-A-H-M-L-D-I-V-S-F-E-R-I-K-E-Y-I-R-A-N-L-G-H-F-T-V-I-T-D-K-C-S-K-R-K-V-C-L-H-H-K-R-I-A-R-L-L-G-I-K-K-I-Y-H-Q-E-Y-K-R-V-V-S-K-V-Y-K-N-Q-T-W"} +{"text": "### FUNCTION When infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities ### SEQUENCE -W-A-G-G-D-A-S-G-E"} +{"text": "### FUNCTION Bacteriocin ### SEQUENCE -A-N-C-S-C-S-T-A-S-D-Y-C-P-I-L-T-F-C-T-T-G-T-A-C-S-Y-T-P-T-G-C-G-T-G-W-V-Y-C-A-C-N-G-N-F-Y"} +{"text": "### FUNCTION C protein is one of the proteins involved in the production and packaging of viral single-stranded DNA ### SEQUENCE -M-R-K-F-N-L-N-L-K-N-S-R-S-S-Y-F-A-T-F-R-H-H-L-N-V-L-A-K-T-D-A-L-D-E-E-K-Y-L-N-M-L-G-A-L-L-K-D-W-F-R-Y-E-E-H-F-V-H-G-K-Q-S-M-L-D-I-L-K-E-R-G-L-L-S-T-S-S-T-D-T-N-H-K-G-N"} +{"text": "### FUNCTION No function has yet been ascribed to K protein ### SEQUENCE -M-K-P-K-T-T-L-L-L-Q-E-L-L-L-L-T-Y-E-L-N-R-S-G-L-L-V-E-N-E-E-I-Q-S-Q-L-K-K-L-E-V-V-L-L-C-N-L-S-P-S-S-Q-R-A-G-K-N"} +{"text": "### FUNCTION May act as an organizer for the correct association of several proteins in the surrounding of the head-tail connector protein gp8 ### SEQUENCE -M-M-T-I-R-P-T-K-S-T-D-F-E-V-F-T-P-A-H-H-D-I-L-E-A-K-A-A-G-I-E-P-S-F-P-D-A-S-E-C-V-T-L-S-L-Y-G-F-P-L-A-I-G-G-N-C-G-D-Q-C-W-F-V-T-S-D-Q-V-W-R-L-S-G-K-A-K-R-K-F-R-K-L-I-M-E-Y-R-D-K-M-L-E-K-Y-D-T-L-W-N-Y-V-W-V-G-N-T-S-H-I-R-F-L-K-T-I-G-A-V-F-H-E-E-Y-T-R-D-G-Q-F-Q-L-F-T-I-T-K-G-G"} +{"text": "### FUNCTION May be associated with transposition functions of transposon Tn903 ### SEQUENCE -M-C-F-T-V-N-G-E-M-Q-L-T-P-D-T-A-A-F-L-A-M-L-F-D-F-P-F-A-F-T-K-D-L-Q-P-G-G-I-N-H-Q-M-R-D-F-T-P-G-E-R-F-E-T-D-I-N-R-L-C-P-P-A-D-T-A-V-I-R-A-A-Q-R-N-I-H-Q-C-K-N-G-I-N-K-A-L-R-S-A-Q-G-Q-P-E-Y-A-F-N-D-Q-H-S-R-D-G-K-V-R-I-A-L-R-S-A-S"} +{"text": "### FUNCTION Involved in resistance to IFN ### SEQUENCE -M-I-Q-S-P-T-S-F-L-I-V-L-I-L-L-W-C-K-L-V-L-S-C-F-R-E-F-I-I-A-L-Q-Q-L-I-Q-V-L-L-Q-I-I-N-S-N-L-Q-P-R-L-T-L-C-H-S-L-D"} +{"text": "### FUNCTION Required for derepression of the P2 prophage helper by P4 ### SEQUENCE -M-R-N-K-K-A-P-Q-T-V-S-A-R-H-D-A-R-E-H-L-S-I-E-A-Y-H-K-L-N-R-A-S-A-V-S-R-F-V-G-G-D-L-I-H-R-E-L-S-G-L-H-Q-L-Y-I-P-H-I-F-S-Y-L-N-E-D-I-D-F-V-L-N-E-L-K-A-K-G-L-C-R-D-F-L-A-Q-Q-K-D-R-G-D-R-T-H-V"} +{"text": "### FUNCTION The presence of the two linear plasmids, termed pGKL1 and pGKL2, in strains of Kluyveromyces lactis confers the killer phenotype to the host cell, by promoting the secretion of a toxin able to inhibit the growth of sensitive strains ### SEQUENCE -M-I-Y-D-K-I-D-T-K-L-I-K-L-G-K-T-N-K-F-S-G-E-E-E-K-S-I-T-S-L-Y-Y-E-D-E-S-F-E-F-S-F-K-N-K-Y-V-K-I-T-K-I-E-T-N-A-Y-G-K-K-F-V-T-I-K-S-K-L-Y-A-D-I-V-E-K-V-A-K-E-L-D-A-V-S-P-I-L-S-D-G-S-F-R-A-T-I-N-D-A-T-S-F-S-K-D-V-G-E-Y-S-F-Y-A-C-V-S-L-Y-F-P-S-I-Y-K-D-T-E-K-T-T-L-Q-V-Y-L-K-E-V-V-V-T-K-I-I-K-N-N-L-E-V-E-F-D-K-L-S-L-A-I"} +{"text": "### FUNCTION The presence of the two linear plasmids, termed pGKL1 and pGKL2, in strains of Kluyveromyces lactis confers the killer phenotype to the host cell, by promoting the secretion of a toxin able to inhibit the growth of sensitive strains ### SEQUENCE -M-N-E-N-I-I-S-N-L-N-Y-F-S-E-I-T-Q-R-T-L-S-A-F-H-F-S-G-T-D-S-T-L-E-D-E-V-E-E-L-K-R-F-V-S-K-N-R-F-K-K-L-I-K-I-D-I-L-D-D-N-R-Y-C-R-H-F-S-D-G-S-K-D-I-V-D-E-E-D-I-N-T-K-V-A-Y-D-K-N-E-L-F-E-V-I-D-R-A-L-S-K-D-I-S-P-I-M-S-I-K-L-S-R-N-I-Q-L-V-E-N-K-K-I-E-N-P-S-E-K-I-F-F-L"} +{"text": "### FUNCTION The presence of the two linear plasmids, termed pGKL1 and pGKL2, in strains of Kluyveromyces lactis confers the killer phenotype to the host cell, by promoting the secretion of a toxin able to inhibit the growth of sensitive strains ### SEQUENCE -M-L-L-Y-L-N-S-T-L-C-S-I-I-S-I-M-Y-K-I-T-N-V-S-F-V-E-Y-Y-S-N-N-V-S-K-D-V-I-Y-S-Y-L-M-N-S-T-C-S-N-K-G-T-I-K-L-N-L-E-S-G-K-R-L-K-Q-E-G-P-Y-I-L-P-P-I-R-W-L-D-S-F-E-K-N-A-E-F-T-I-L-C-E-V-D-D-I-K"} +{"text": "### FUNCTION This protein is involved in control of the biosynthesis of tryptophan ### SEQUENCE -M-A-L-P-S-A-L-W-W-P-G"} +{"text": "### FUNCTION This protein is involved in regulating the plasmid copy-number Increasing the level of this protein results in a higher plasmid copy-number ### SEQUENCE -M-A-T-H-K-P-I-N-I-L-E-A-F-A-A-A-P-P-P-L-D-Y-V-L-P-N-M-V-A-G-T-V-G-A-L-V-S-P-G-G-A-G-K-S-M-L-A-L-Q-L-A-A-Q-I-A-G-G-P-D-L-L-E-V-G-E-L-P-T-G-P-V-I-Y-L-P-A-E-D-P-P-T-A-I-H-H-R-L-H-A-L-G-A-H"} +{"text": "### FUNCTION This N protein may have, like the lambda N protein, an antitermination activity ### SEQUENCE -M-I-D-D-I-K-R-I-D-S-M-I-N-A-L-R-N-M-K-Q-D-I-K-R-Q-Q-K-L-S-E-I-N-S-L-D-L-S-P-K-Q-A-Q-K-R-N-A-D-A-D-W-I-A-M-E-Q-I-K-R-R-H-E-L-H-A-L-S-V-E-L-G-F-A-E-R-R-E-S-Y-A-P-F-E-L-T-D-G-W-H-R-F-D-H-K-P-R-E-P-Q"} +{"text": "### FUNCTION Binds one copper ion per molecule but does not bind the galactose oxidase apoenzyme It may inactivate the enzyme by binding to its prosthetic copper group ### SEQUENCE -A-G-Q-N-T-E-S"} +{"text": "### FUNCTION Not yet known ### SEQUENCE -M-L-S-G-E-A-E-Q-L-R-L-K-H-L-V-H-C-R-R-H-K-C-F-A-R-D-S-G-E-F-C-Y-F-E-L-P-E-D-H-I-E-G-P-A-H-G-V-R-L-T-A-Q-G-E-L-A-R-S-L-I-R-E-F-T-Q-R-P-L-L-V-E-R-D-R-G-P-C-V-L-T-V-I-C-N-C-P-N-L-G-L-H-Q-D-L-C-C-H-L-C-A-E-Y-N-K-Y-R-N"} +{"text": "### FUNCTION Broad mercury transporter that mediates the transport of both CH across the membrane ### SEQUENCE -M-N-N-P-E-R-L-P-S-E-T-H-K-P-I-T-G-Y-L-W-G-G-L-A-V-L-T-C-P-C-H-L-P-I-L-A-V-V-L-A-G-T-T-A-G-A-F-L-G-E-H-W-V-I-A-A-L-G-L-T-G-L-F-L-L-S-L-S-R-A-L-R-A-F-R-E-R-E"} +{"text": "### FUNCTION Inhibits the host uracil-DNA glycosylase , an enzyme which removes uracil residues from DNA by the base excision repair Interacts with host uracil-DNA glycosylase and prevents the latter from binding to DNA Since the viral DNA polymerase efficiently incorporates dUMP into DNA, the virus needs to prevent the deleterious effect caused by host UDG when it eliminates uracil residues present in the viral genome ### SEQUENCE -M-V-Q-N-D-F-L-D-S-Y-D-V-T-M-L-L-Q-D-D-N-G-K-Q-Y-Y-E-Y-H-K-G-L-S-L-S-D-F-E-V-L-Y-G-N-T-V-D-E-I-I-K-L-R-V-D-K-I-S"} +{"text": "### FUNCTION Ral interferes with the cleavage of DNA by Ecoli EcoK restriction-modification system, by modifying the activity of the host methylase This modulation allows incoming, unmodified phages to escape the host's restriction system ### SEQUENCE -M-T-T-T-I-D-K-N-Q-W-C-G-Q-F-K-R-C-N-G-C-K-L-Q-S-E-C-M-V-K-P-E-E-M-F-P-V-M-E-D-G-K-Y-V-D-K-W-A-I-R-T-T-A-M-I-A-R-E-L-G-K-Q-L-D-E-D-A-R-L-C-S-L-S-V-F-D-A"} +{"text": "### FUNCTION This peptide stimulates the transport of dentinal fluid, which is important for the prevention of dental caries ### SEQUENCE -G-V-I-A-W-E-L-Q-H-N-E-P-G-R-K-D-S-T-A-G"} +{"text": "### FUNCTION Involved in DNA transformation ### SEQUENCE -M-A-I-I-K-P-H-A-N-K-N-R-T-T-S-P-I-E-R-P-E-S-L-I-E-E-M-S-G-S-N-P-P-I-G-F-T-S-L-D-L-A-M-I-E-L-E-D-F-V-H-R-C-P-L-P-G-D-N-L-A-G-Q-K-E"} +{"text": "### FUNCTION Assembly factor active in membrane morphogenesis ### SEQUENCE -M-V-I-G-L-L-K-Y-L-T-P-A-V-K-V-Q-M-A-A-R-A-L-G-L-S-P-A-E-V-A-A-I-D-G-T-L-G-R-V-S-A-M-P-A-V-A-V-V-L-G-G-K-P-L-S-L-A-T-I-A-S-V-V-S-D-A-N-P-S-A-T-V-G-A-L-M-P-A-V-Q-G-M-V-S-S-D-E-G-A-S-A-L-A-K-T-V-V-G-F-M-E-S-D-P-N-S-D-V-L-V-Q-L-L-H-K-V-S-N-L-P-I-V-G-F-G-D-T-Q-Y-A-D-P-A-D-F-L-A-K-G-V-F-P-L-I-R-K-P-E-V-E-V-Q-A-A-P-F-T-C-R-Q-C-D-H-V-D-H-I-T-D-V-P-Q-T-S-T-F-V-H-K-C-T-S-C-G-F-V-Q-M-V-H-R-K-D-V-P"} +{"text": "### FUNCTION This is an inhibitor of the host It is implicated in DNA replication ### SEQUENCE -M-M-M-G-R-I-Y-S-G-N-L-N-D-Y-K-D-A-V-A-R-L-Q-E-D-H-D-V-T-V-K-M-E-S-F-S-Y-E-N-P-A-K-M-C-R-S-C-G-E-V-L-S-V-F-T-R-S-G-H-L-V-A-S-R-T-F-E-H-S-D-S-D-V-Q-I-N-A-Q-T-A-W-L-R-K-V-H-S-E-L-K-H-W-K"} +{"text": "### FUNCTION The function of this late gene protein is unknown ### SEQUENCE -M-L-Q-H-H-W-N-K-P-D-L-E-A-R-F-P-V-N-S-V-V-R-Y-S-G-G-G-L-K-R-I-L-G-M-S-G-V-V-T-G-H-S-H-T-G-L-V-K-V-R-F-G-T-Q-Y-A-E-V-L-P-N-N-L-I-P-L-P-K-A-D-V-K-T-P-N-V-E-A-P-K-T-E-V-K-S-D-V-T-H-P-N-H-Y-M-L-F-D-N-V-E-A-I-E-V-I-A-R-S-M-T-V-E-A-F-R-G-Y-C-L-G-N-I-L-K-Y-R-L-R-A-G-K-K-S-E-L-A-T-M-D-K-D-L-K-K-A-A-F-Y-Q-E-L-F-D-K-H-R-G-L-C-Y-D-A-S"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-M-E-W-F-Y-Q-I-P-G-V-D-E-L-R-S-A-E-S-F-F-Q-F-F-A-V-P-Y-Q-P-E-L-L-G-R-C-S-L-P-V-L-A-T-F-H-R-K-L-R-A-E-V-P-L-Q-N-R-L-E-D-N-D-R-A-P-W-L-L-A-R-R-L-L-A-E-S-Y-Q-Q-Q-F-Q-E-S-G-T"} +{"text": "### FUNCTION Organic hydroperoxide detoxification protein Confers increased resistance to tert-butyl hydroperoxide killing ### SEQUENCE -M-A-S-P-E-K-V-L-Y-T-A-H-A-T-A-T-G-G-R-E-G-R-A-V-S-S-D-K-A-L-D-A-K-L-S-T-P-R-E-L-G-G-A-G-G-D-G-T-N-P-E-Q-L-F-A-A-G-Y-A-A-C-F-I-G-A-M-K-A-V-A-A-Q-D-K-L-K-L-P-G-E-V-S-I-D-S-S-V-G-I-G-Q-I-P-G-G-F-G-I-V-V-E-L-R-I-A-V-P-G-M-D-K-A-E-L-Q-T-L-V-D-K-A-H-Q-V-C-P-Y-S-N-A-T-R-G-N-I-D-V-T-L-T-L-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-L-A-L-V-P-I-Q-F-Y-R-Y-A-I-S-P-L-M-A-N-H-C-R-F-F-P-S-C-S-C-Y-A-Y-E-A-I-E-N-H-G-I-W-R-G-G-W-L-A-V-R-R-L-G-R-C-H-P-W-N-D-G-G-Y-D-P-V-P-P-A-P-S-S-R-T-S-S-I-A-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-L-A-L-V-P-I-Q-F-Y-R-Y-A-I-S-P-L-M-A-N-H-C-R-F-F-P-S-C-S-C-Y-A-Y-E-A-I-E-N-H-G-I-W-R-G-G-W-L-A-V-R-R-L-G-R-C-H-P-W-N-D-G-G-Y-D-P-V-P-P-A-P-S-S-R-T-S-S-I-A-E"} +{"text": "### FUNCTION The imp operon is involved in UV protection and mutation, however the ImpC protein is not essential for these functions ### SEQUENCE -M-I-R-I-E-I-L-F-D-R-Q-S-T-K-N-L-K-S-G-T-L-Q-A-L-Q-N-E-I-E-Q-R-L-K-P-H-Y-P-E-I-W-L-R-I-D-Q-G-S-A-P-S-V-S-V-T-G-A-R-N-D-K-D-K-E-R-I-L-S-L-L-E-E-I-W-Q-D-D-S-W-L-P-A-A"} +{"text": "### FUNCTION Affects survival in macrophages ### SEQUENCE -M-F-V-E-L-V-Y-D-K-R-N-V-E-G-L-P-G-A-R-E-I-I-L-N-E-L-T-K-R-V-H-Q-L-F-P-D-A-Q-V-K-V-K-P-M-Q-A-N-A-L-N-S-D-C-T-K-T-E-K-E-R-L-H-R-M-L-E-E-M-F-E-E-A-D-M-W-L-V-A-E"} +{"text": "### FUNCTION Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells ### SEQUENCE -M-Q-H-L-D-I-A-E-L-V-R-S-A-L-E-V-S-G-C-D-P-S-L-I-G-G-I-D-S-H-S-T-I-V-L-D-L-F-A-L-P-S-I-C-I-S-V-K-D-D-D-V-W-I-W-A-Q-L-G-A-D-S-M-V-V-L-Q-Q-R-A-Y-E-I-L-M-T-I-M-E-G-C-H-F-A-R-G-G-Q-L-L-L-G-E-Q-N-G-E-L-T-L-K-A-L-V-H-P-D-F-L-S-D-G-E-K-F-S-T-A-L-N-G-F-Y-N-Y-L-E-V-F-S-R-S-L-M-R"} +{"text": "### FUNCTION Not essential for flagellar formation and function ### SEQUENCE -M-R-K-W-L-A-L-L-L-F-P-L-T-V-Q-A-A-G-E-G-A-W-Q-D-S-G-M-G-V-T-L-N-Y-R-G-V-S-A-S-S-S-P-L-S-A-R-Q-P-V-S-G-V-M-T-L-V-A-W-R-Y-E-L-N-G-P-T-P-A-G-L-R-V-R-L-C-S-Q-S-R-C-V-E-L-D-G-Q-S-G-T-T-H-G-F-A-H-V-P-A-V-E-P-L-R-F-V-W-E-V-P-G-G-G-R-L-I-P-A-L-K-V-R-S-N-Q-V-I-V-N-Y-R"} +{"text": "### FUNCTION Plays a role in synthesis, processing and/or stability of 23S rRNA ### SEQUENCE -M-Q-K-V-K-L-P-L-T-L-D-P-V-R-T-A-Q-K-R-L-D-Y-Q-G-I-Y-T-P-D-Q-V-E-R-V-A-E-S-V-V-S-V-D-S-D-V-E-C-S-M-S-F-A-I-D-N-Q-R-L-A-V-L-T-G-D-A-V-V-T-V-S-L-E-C-Q-R-C-G-K-P-F-T-H-Q-V-H-T-T-Y-C-F-S-P-V-R-S-D-E-Q-A-E-A-L-P-E-A-Y-E-P-I-E-V-N-E-F-G-E-I-D-L-L-A-T-V-E-D-E-I-I-L-A-L-P-V-V-P-V-H-D-S-E-H-C-E-V-S-E-A-D-M-V-F-G-E-L-P-D-E-A-Q-K-P-N-P-F-A-V-L-A-S-L-K-R-K"} +{"text": "### FUNCTION May be involved in the biogenesis of curli organelles ### SEQUENCE -M-K-R-Y-L-T-W-I-V-A-A-E-L-L-F-A-T-G-N-L-H-A-N-E-V-E-V-E-V-P-G-L-L-T-D-H-T-V-S-S-I-G-H-E-F-Y-R-A-F-S-D-K-W-E-S-E-Y-T-G-N-L-T-I-N-E-R-P-S-A-R-W-G-S-W-I-T-I-T-V-N-Q-D-V-I-F-Q-T-F-L-F-P-M-K-R-D-F-E-K-T-V-V-F-A-L-A-Q-T-E-E-A-L-N-R-R-Q-I-D-Q-T-L-L-S-T-S-D-L-A-R-D-E-F"} +{"text": "### FUNCTION May be involved in the biogenesis of curli organelles ### SEQUENCE -M-R-V-K-H-A-V-V-L-L-M-L-F-S-P-L-T-W-A-G-N-M-T-F-Q-F-R-N-P-N-F-G-G-N-P-N-N-G-S-F-L-L-N-S-A-Q-A-Q-N-S-Y-K-D-P-A-Y-D-N-D-F-G-I-E-T-P-S-A-L-D-N-F-T-Q-A-I-Q-S-Q-I-L-G-G-L-L-T-N-I-N-T-G-K-P-G-R-M-V-T-N-D-F-I-I-D-I-A-N-R-D-G-Q-L-Q-L-N-V-T-D-R-K-T-G-R-T-S-T-I-E-V-S-G-L-Q-T-Q-S-T-D-F"} +{"text": "### FUNCTION Necessary for the secretion of IPA invasins ### SEQUENCE -M-S-V-T-V-P-N-D-D-W-T-L-S-S-L-S-E-T-F-D-D-G-T-Q-T-L-Q-G-E-L-T-L-A-L-D-K-L-A-K-N-P-S-N-P-Q-L-L-A-E-Y-Q-S-K-L-S-E-Y-T-L-Y-R-N-A-Q-S-N-T-V-K-V-I-K-D-V-D-A-A-I-I-Q-N-F-R"} +{"text": "### FUNCTION Necessary for the secretion of IPA invasins ### SEQUENCE -M-N-Y-I-Y-P-V-N-Q-V-D-I-I-K-A-S-D-F-Q-S-Q-E-I-S-S-L-E-D-V-V-S-A-K-Y-S-D-I-K-M-D-T-D-I-Q-V-S-Q-I-M-E-M-V-S-N-P-E-S-L-N-P-E-S-L-A-K-L-Q-T-T-L-S-N-Y-S-I-G-V-S-L-A-G-T-L-A-R-K-T-V-S-A-V-E-T-L-L-K-S"} +{"text": "### FUNCTION Necessary for the secretion of IPA invasins ### SEQUENCE -M-I-R-M-D-G-I-Y-K-K-Y-L-S-I-I-F-D-P-A-F-Y-I-N-R-N-R-L-N-L-P-S-E-L-L-E-N-G-V-I-R-S-E-I-N-N-L-I-I-N-K-Y-D-L-N-C-D-I-E-P-L-S-G-V-T-A-M-F-V-A-N-W-N-L-L-P-A-V-A-Y-F-I-G-S-Q-E-S-R-L-I-N-H-S-E-M-V-I-S-Y-Y-G-G-K-I-S-K-Q-G-E-A-A-I-R-S-G-F-W-H-L-I-A-W-K-E-N-I-S-V-G-I-Y-E-R-I-N-L-L-F-N-P-I-A-L-E-G-N-Y-T-P-V-E-R-N-L-S-R-L-N-E-G-M-Q-Y-A-K-R-H-F-T-G-I-Q-T-S-C-L"} +{"text": "### FUNCTION Imparts immunity to lactococcin-A to naturally sensitive host strains ### SEQUENCE -M-K-K-K-Q-I-E-F-E-N-E-L-R-S-M-L-A-T-A-L-E-K-D-I-S-Q-E-E-R-N-A-L-N-I-A-E-K-A-L-D-N-S-E-Y-L-P-K-I-I-L-N-L-R-K-A-L-T-P-L-A-I-N-R-T-L-N-H-D-L-S-E-L-Y-K-F-I-T-S-S-K-A-S-N-K-N-L-G-G-G-L-I-M-S-W-G-R-L-F"} +{"text": "### FUNCTION Required for the formation of functionally normal spores Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor ### SEQUENCE -M-N-F-Y-V-N-Q-S-I-I-I-N-S-I-K-I-D-S-I-T-T-S-S-V-F-Q-I-G-T-A-G-S-I-K-A-L-S-K-F-S-N-T-G-G-F-T-E-P-L-R-P-L-Q-A-K-G-Q-I-I-S-I-K-P-S-T-S-S-S"} +{"text": "### FUNCTION Required for the formation of functionally normal spores Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor ### SEQUENCE -M-N-L-N-V-V-N-R-E-L-K-V-G-Q-I-K-M-N-G-V-S-S-S-A-L-F-L-I-G-D-A-N-L-L-I-L-S-S-I-L-D-T-P-F-E-T-V-T-E-G-P-F-V-P-L-V-T-D-V-P-P-T-P-G"} +{"text": "### FUNCTION Probable antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to cognate MazF1 toxin and counteracts its endoribonuclease activity ### SEQUENCE -M-P-F-L-V-A-L-S-G-I-I-S-G-V-R-D-H-S-M-T-V-R-L-D-Q-Q-T-R-Q-R-L-Q-D-I-V-K-G-G-Y-R-S-A-N-A-A-I-V-D-A-I-N-K-R-W-E-A-L-H-D-E-Q-L-D-A-A-Y-A-A-A-I-H-D-N-P-A-Y-P-Y-E-S-E-A-E-R-S-A-A-R-A-R-R-N-A-R-Q-Q-R-S-A-Q"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Displays esterase activity toward palmitoyl-CoA and pNP-butyrate ### SEQUENCE -M-S-T-L-L-Y-L-H-G-F-N-S-S-P-R-S-A-K-A-S-L-L-K-N-W-L-A-E-H-H-P-D-V-E-M-I-I-P-Q-L-P-P-Y-P-S-D-A-A-E-L-L-E-S-I-V-L-E-H-G-G-D-S-L-G-I-V-G-S-S-L-G-G-Y-Y-A-T-W-L-S-Q-C-F-M-L-P-A-V-V-V-N-P-A-V-R-P-F-E-L-L-T-D-Y-L-G-Q-N-E-N-P-Y-T-G-Q-Q-Y-V-L-E-S-R-H-I-Y-D-L-K-V-M-Q-I-D-P-L-E-A-P-D-L-I-W-L-L-Q-Q-T-G-D-E-V-L-D-Y-R-Q-A-V-A-Y-Y-A-S-C-R-Q-T-V-I-E-G-G-N-H-A-F-T-G-F-E-D-Y-F-N-P-I-V-D-F-L-G-L-H-H-L"} +{"text": "### FUNCTION Displays esterase activity toward palmitoyl-CoA and pNP-butyrate ### SEQUENCE -M-S-T-L-L-Y-L-H-G-F-N-S-S-P-R-S-A-K-A-S-L-L-K-N-W-L-A-E-H-H-P-D-V-E-M-I-I-P-Q-L-P-P-Y-P-S-D-A-A-E-L-L-E-S-I-V-L-E-H-G-G-D-S-L-G-I-V-G-S-S-L-G-G-Y-Y-A-T-W-L-S-Q-C-F-M-L-P-A-V-V-V-N-P-A-V-R-P-F-E-L-L-T-D-Y-L-G-Q-N-E-N-P-Y-T-G-Q-Q-Y-V-L-E-S-R-H-I-Y-D-L-K-V-M-Q-I-D-P-L-E-A-P-D-L-I-W-L-L-Q-Q-T-G-D-E-V-L-D-Y-R-Q-A-V-A-Y-Y-A-S-C-R-Q-T-V-I-E-G-G-N-H-A-F-T-G-F-E-D-Y-F-N-P-I-V-D-F-L-G-L-H-H-L"} +{"text": "### FUNCTION Displays esterase activity toward palmitoyl-CoA and pNP-butyrate ### SEQUENCE -M-S-T-L-L-Y-L-H-G-F-N-S-S-P-R-S-A-K-A-S-L-L-K-N-W-L-A-E-H-H-P-D-V-E-M-I-I-P-Q-L-P-P-Y-P-S-D-A-A-E-L-L-E-S-I-V-L-E-H-G-G-D-S-L-G-I-V-G-S-S-L-G-G-Y-Y-A-T-W-L-S-Q-C-F-M-L-P-A-V-V-V-N-P-A-V-R-P-F-E-L-L-T-D-Y-L-G-Q-N-E-N-P-Y-T-G-Q-Q-Y-V-L-E-S-R-H-I-Y-D-L-K-V-M-Q-I-D-P-L-E-A-P-D-L-I-W-L-L-Q-Q-T-G-D-E-V-L-D-Y-R-Q-A-V-A-Y-Y-A-S-C-R-Q-T-V-I-E-G-G-N-H-A-F-T-G-F-E-D-Y-F-N-P-I-V-D-F-L-G-L-H-H-L"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-A-Y-K-H-I-G-V-A-I-S-G-N-E-E-D-A-L-L-V-N-K-A-L-E-L-A-R-H-N-D-A-H-L-T-L-I-H-I-D-D-G-L-S-E-L-Y-P-G-I-Y-F-P-A-T-E-D-I-L-Q-L-L-K-N-K-S-D-N-K-L-Y-K-L-T-K-N-I-Q-W-P-K-T-K-L-R-I-E-R-G-E-M-P-E-T-L-L-E-I-M-Q-K-E-Q-C-D-L-L-V-C-G-H-H-H-S-F-I-N-R-L-M-P-A-Y-R-G-M-I-N-K-M-S-A-D-L-L-I-V-P-F-I-D-K"} +{"text": "### FUNCTION Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway ### SEQUENCE -M-F-V-D-R-Q-R-I-D-L-L-N-R-L-I-D-A-R-V-D-L-A-A-Y-V-Q-L-R-K-A-K-G-Y-M-S-V-S-E-S-N-H-L-R-D-N-F-F-K-L-N-R-E-L-H-D-K-S-L-R-L-N-L-H-L-D-Q-E-E-W-S-A-L-H-H-A-E-E-A-L-A-T-A-A-V-C-L-M-S-G-H-H-D-C-P-T-V-I-T-V-N-A-D-K-L-E-N-C-L-M-S-L-T-L-S-I-Q-S-L-Q-K-H-A-M-L-E-K-A"} +{"text": "### FUNCTION Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway ### SEQUENCE -M-F-V-D-R-Q-R-I-D-L-L-N-R-L-I-D-A-R-V-D-L-A-A-Y-V-Q-L-R-K-A-K-G-Y-M-S-V-S-E-S-N-H-L-R-D-N-F-F-K-L-N-R-E-L-H-D-K-S-L-R-L-N-L-H-L-D-Q-E-E-W-S-A-L-H-H-A-E-E-A-L-A-T-A-A-V-C-L-M-S-G-H-H-D-C-P-T-V-I-T-V-N-A-D-K-L-E-N-C-L-M-S-L-T-L-S-I-Q-S-L-Q-K-H-A-M-L-E-K-A"} +{"text": "### FUNCTION Plays a role in synthesis, processing and/or stability of 23S rRNA ### SEQUENCE -M-Q-K-V-K-L-P-L-T-L-D-P-V-R-T-A-Q-K-R-L-D-Y-Q-G-I-Y-T-P-D-Q-V-E-R-V-A-E-S-V-V-S-V-D-S-D-V-E-C-S-M-S-F-A-I-D-N-Q-R-L-A-V-L-N-G-D-A-K-V-T-V-T-L-E-C-Q-R-C-G-K-P-F-T-H-Q-V-Y-T-T-Y-C-F-S-P-V-R-S-D-E-Q-A-E-A-L-P-E-A-Y-E-P-I-E-V-N-E-F-G-E-I-D-L-L-A-M-V-E-D-E-I-I-L-A-L-P-V-V-P-V-H-D-S-E-H-C-E-V-S-E-A-D-M-V-F-G-E-L-P-E-E-A-Q-K-P-N-P-F-A-V-L-A-S-L-K-R-K"} +{"text": "### FUNCTION Plays a role in synthesis, processing and/or stability of 23S rRNA ### SEQUENCE -M-Q-K-V-K-L-P-L-T-L-D-P-V-R-T-A-Q-K-R-L-D-Y-Q-G-I-Y-T-P-D-Q-V-E-R-V-A-E-S-V-V-S-V-D-S-D-V-E-C-S-M-S-F-A-I-D-N-Q-R-L-A-V-L-N-G-D-A-K-V-T-V-T-L-E-C-Q-R-C-G-K-P-F-T-H-Q-V-Y-T-T-Y-C-F-S-P-V-R-S-D-E-Q-A-E-A-L-P-E-A-Y-E-P-I-E-V-N-E-F-G-E-I-D-L-L-A-M-V-E-D-E-I-I-L-A-L-P-V-V-P-V-H-D-S-E-H-C-E-V-S-E-A-D-M-V-F-G-E-L-P-E-E-A-Q-K-P-N-P-F-A-V-L-A-S-L-K-R-K"} +{"text": "### FUNCTION Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway ### SEQUENCE -M-E-K-N-N-E-V-I-Q-T-H-P-L-V-G-W-D-I-S-T-V-D-S-Y-D-A-L-M-L-R-L-H-Y-Q-T-P-N-K-S-E-Q-E-G-T-E-V-G-Q-T-L-W-L-T-T-D-V-A-R-Q-F-I-S-I-L-E-A-G-I-A-K-I-E-S-G-D-F-Q-V-N-E-Y-R-R-H"} +{"text": "### FUNCTION Involved in SOS regulation Inhibits RecA by preventing RecA to bind ssDNA Can displace ssDNA from RecA ### SEQUENCE -M-R-I-E-V-T-I-A-K-T-S-P-L-P-A-G-A-I-D-A-L-A-G-E-L-S-R-R-I-Q-Y-A-F-P-D-N-E-G-H-V-S-V-R-Y-A-A-A-N-N-L-S-V-I-G-A-T-K-E-D-K-Q-R-I-S-E-I-L-Q-E-T-W-E-S-A-D-D-W-F-V-S-E"} +{"text": "### FUNCTION Involved in SOS regulation Inhibits RecA by preventing RecA to bind ssDNA Can displace ssDNA from RecA ### SEQUENCE -M-R-I-E-V-T-I-A-K-T-S-P-L-P-A-G-A-I-D-A-L-A-G-E-L-S-R-R-I-Q-Y-A-F-P-D-N-E-G-H-V-S-V-R-Y-A-A-A-N-N-L-S-V-I-G-A-T-K-E-D-K-Q-R-I-S-E-I-L-Q-E-T-W-E-S-A-D-D-W-F-V-S-E"} +{"text": "### FUNCTION Required for full activity of the EbgA enzyme Exact function not known ### SEQUENCE -M-R-I-I-D-N-L-E-Q-F-R-Q-I-Y-A-S-G-K-K-W-Q-R-C-V-E-A-I-E-N-I-D-N-I-Q-P-G-V-A-H-S-I-G-D-S-L-T-Y-R-V-E-T-D-S-A-T-D-A-L-F-T-G-H-R-R-Y-F-E-V-H-Y-Y-L-Q-G-Q-Q-K-I-E-Y-A-P-K-E-T-L-Q-V-V-E-Y-Y-R-D-E-T-D-R-E-Y-L-K-G-C-G-E-T-V-E-V-H-E-G-Q-I-V-I-C-D-I-H-E-A-Y-R-F-I-C-N-N-A-V-K-K-V-V-L-K-V-T-I-E-D-G-Y-F-H-N-K"} +{"text": "### FUNCTION This protein is involved in control of the biosynthesis of phenylalanine ### SEQUENCE -M-K-H-I-P-F-F-F-A-F-F-F-T-F-P"} +{"text": "### FUNCTION Involved in control of the biosynthesis of leucine ### SEQUENCE -M-T-H-I-V-R-F-I-G-L-L-L-L-N-A-S-S-L-R-G-R-R-V-S-G-I-Q-H"} +{"text": "### FUNCTION Involved in control of the biosynthesis of leucine ### SEQUENCE -M-T-H-I-V-R-F-I-G-L-L-L-L-N-A-S-S-L-R-G-R-R-V-S-G-I-Q-H"} +{"text": "### FUNCTION Involved in control of the biosynthesis of leucine ### SEQUENCE -M-T-H-I-V-R-F-I-G-L-L-L-L-N-A-S-S-L-R-G-R-R-V-S-G-I-Q-H"} +{"text": "### FUNCTION This protein is involved in control of the biosynthesis of tryptophan ### SEQUENCE -M-K-A-I-F-V-L-K-G-W-W-R-T-S"} +{"text": "### FUNCTION This protein is involved in control of the biosynthesis of tryptophan ### SEQUENCE -M-K-A-I-F-V-L-K-G-W-W-R-T-S"} +{"text": "### FUNCTION This protein is involved in control of the biosynthesis of tryptophan ### SEQUENCE -M-K-A-I-F-V-L-K-G-W-W-R-T-S"} +{"text": "### FUNCTION Absolutely required for transposition of IS1 ### SEQUENCE -M-A-S-V-S-I-S-C-P-S-C-S-A-T-D-G-V-V-R-N-G-K-S-T-A-G-H-Q-R-Y-L-C-S-H-C-R-K-T-W-Q-L-Q-F-T-Y-T-A-S-Q-P-G-T-H-Q-K-I-I-D-M-A-M-N-G-V-G-C-R-A-T-A-R-I-M-G-V-G-L-N-T-I-L-R-H-L-K-N-S-G-R-S-R"} +{"text": "### FUNCTION Potential transcriptional activator of carnitine metabolism ### SEQUENCE -M-C-E-G-Y-V-E-K-P-L-Y-L-L-I-A-E-W-M-M-A-E-N-R-W-V-I-A-R-E-I-S-I-H-F-D-I-E-H-S-K-A-V-N-T-L-T-Y-I-L-S-E-V-T-E-I-S-C-E-V-K-M-I-P-N-K-L-E-G-R-G-C-Q-C-Q-R-L-V-K-V-V-D-I-D-E-Q-I-Y-A-R-L-R-N-N-S-R-E-K-L-V-G-V-R-K-T-P-R-I-P-A-V-P-L-T-E-L-N-R-E-Q-K-W-Q-M-M-L-S-K-S-M-R-R"} +{"text": "### FUNCTION Might be a regulator of the sodium-potassium/proton antiporter ChaA ### SEQUENCE -M-P-Y-K-T-K-S-D-L-P-E-S-V-K-H-V-L-P-S-H-A-Q-D-I-Y-K-E-A-F-N-S-A-W-D-Q-Y-K-D-K-E-D-R-R-D-D-A-S-R-E-E-T-A-H-K-V-A-W-A-A-V-K-H-E-Y-A-K-G-D-D-D-K-W-H-K-K-S"} +{"text": "### FUNCTION Might be a regulator of the sodium-potassium/proton antiporter ChaA ### SEQUENCE -M-P-Y-K-T-K-S-D-L-P-E-S-V-K-H-V-L-P-S-H-A-Q-D-I-Y-K-E-A-F-N-S-A-W-D-Q-Y-K-D-K-E-D-R-R-D-D-A-S-R-E-E-T-A-H-K-V-A-W-A-A-V-K-H-E-Y-A-K-G-D-D-D-K-W-H-K-K-S"} +{"text": "### FUNCTION May be involved in the biogenesis of curli organelles ### SEQUENCE -M-K-R-Y-L-R-W-I-V-A-A-E-F-L-F-A-A-G-N-L-H-A-V-E-V-E-V-P-G-L-L-T-D-H-T-V-S-S-I-G-H-D-F-Y-R-A-F-S-D-K-W-E-S-D-Y-T-G-N-L-T-I-N-E-R-P-S-A-R-W-G-S-W-I-T-I-T-V-N-Q-D-V-I-F-Q-T-F-L-F-P-L-K-R-D-F-E-K-T-V-V-F-A-L-I-Q-T-E-E-A-L-N-R-R-Q-I-N-Q-A-L-L-S-T-G-D-L-A-H-D-E-F"} +{"text": "### FUNCTION May be involved in the biogenesis of curli organelles ### SEQUENCE -M-K-R-Y-L-R-W-I-V-A-A-E-F-L-F-A-A-G-N-L-H-A-V-E-V-E-V-P-G-L-L-T-D-H-T-V-S-S-I-G-H-D-F-Y-R-A-F-S-D-K-W-E-S-D-Y-T-G-N-L-T-I-N-E-R-P-S-A-R-W-G-S-W-I-T-I-T-V-N-Q-D-V-I-F-Q-T-F-L-F-P-L-K-R-D-F-E-K-T-V-V-F-A-L-I-Q-T-E-E-A-L-N-R-R-Q-I-N-Q-A-L-L-S-T-G-D-L-A-H-D-E-F"} +{"text": "### FUNCTION May be involved in the biogenesis of curli organelles ### SEQUENCE -M-R-V-K-H-A-V-V-L-L-M-L-I-S-P-L-S-W-A-G-T-M-T-F-Q-F-R-N-P-N-F-G-G-N-P-N-N-G-A-F-L-L-N-S-A-Q-A-Q-N-S-Y-K-D-P-S-Y-N-D-D-F-G-I-E-T-P-S-A-L-D-N-F-T-Q-A-I-Q-S-Q-I-L-G-G-L-L-S-N-I-N-T-G-K-P-G-R-M-V-T-N-D-Y-I-V-D-I-A-N-R-D-G-Q-L-Q-L-N-V-T-D-R-K-T-G-Q-T-S-T-I-Q-V-S-G-L-Q-N-N-S-T-D-F"} +{"text": "### FUNCTION May be involved in the biogenesis of curli organelles ### SEQUENCE -M-R-V-K-H-A-V-V-L-L-M-L-I-S-P-L-S-W-A-G-T-M-T-F-Q-F-R-N-P-N-F-G-G-N-P-N-N-G-A-F-L-L-N-S-A-Q-A-Q-N-S-Y-K-D-P-S-Y-N-D-D-F-G-I-E-T-P-S-A-L-D-N-F-T-Q-A-I-Q-S-Q-I-L-G-G-L-L-S-N-I-N-T-G-K-P-G-R-M-V-T-N-D-Y-I-V-D-I-A-N-R-D-G-Q-L-Q-L-N-V-T-D-R-K-T-G-Q-T-S-T-I-Q-V-S-G-L-Q-N-N-S-T-D-F"} +{"text": "### FUNCTION May be involved in the biogenesis of curli organelles ### SEQUENCE -M-R-V-K-H-A-V-V-L-L-M-L-I-S-P-L-S-W-A-G-T-M-T-F-Q-F-R-N-P-N-F-G-G-N-P-N-N-G-A-F-L-L-N-S-A-Q-A-Q-N-S-Y-K-D-P-S-Y-N-D-D-F-G-I-E-T-P-S-A-L-D-N-F-T-Q-A-I-Q-S-Q-I-L-G-G-L-L-S-N-I-N-T-G-K-P-G-R-M-V-T-N-D-Y-I-V-D-I-A-N-R-D-G-Q-L-Q-L-N-V-T-D-R-K-T-G-Q-T-S-T-I-Q-V-S-G-L-Q-N-N-S-T-D-F"} +{"text": "### FUNCTION Regulatory protein for the formate hydrogenlyase system Could act by directly interacting with FhlA or by preventing the binding of FhlA to the upstream activatory sequence ### SEQUENCE -M-T-I-W-E-I-S-E-K-A-D-Y-I-A-Q-R-H-R-R-L-Q-D-Q-W-H-I-Y-C-N-S-L-V-Q-G-I-T-L-S-K-A-R-L-H-H-A-M-S-C-A-P-D-K-E-L-C-F-V-L-F-E-H-F-R-I-Y-V-T-L-A-D-G-F-N-S-H-T-I-E-Y-Y-V-E-T-K-D-G-E-D-K-Q-R-I-A-Q-A-Q-L-S-I-D-G-M-I-D-G-K-V-N-I-R-D-R-E-Q-V-L-E-H-Y-L-E-K-I-A-G-V-Y-D-S-L-Y-T-A-I-E-N-N-V-P-V-N-L-S-Q-L-V-K-G-Q-S-P-A-A"} +{"text": "### FUNCTION Regulatory protein for the formate hydrogenlyase system Could act by directly interacting with FhlA or by preventing the binding of FhlA to the upstream activatory sequence ### SEQUENCE -M-T-I-W-E-I-S-E-K-A-D-Y-I-A-Q-R-H-R-R-L-Q-D-Q-W-H-I-Y-C-N-S-L-V-Q-G-I-T-L-S-K-A-R-L-H-H-A-M-S-C-A-P-D-K-E-L-C-F-V-L-F-E-H-F-R-I-Y-V-T-L-A-D-G-F-N-S-H-T-I-E-Y-Y-V-E-T-K-D-G-E-D-K-Q-R-I-A-Q-A-Q-L-S-I-D-G-M-I-D-G-K-V-N-I-R-D-R-E-Q-V-L-E-H-Y-L-E-K-I-A-G-V-Y-D-S-L-Y-T-A-I-E-N-N-V-P-V-N-L-S-Q-L-V-K-G-Q-S-P-A-A"} +{"text": "### FUNCTION Seems to be required for the conversion of a precursor form of the large subunit of hydrogenlyase into a mature form ### SEQUENCE -M-S-E-K-V-V-F-S-Q-L-S-R-K-F-I-D-E-N-D-A-T-P-A-E-A-Q-Q-V-V-Y-Y-S-L-A-I-G-H-H-L-G-V-I-D-C-L-E-A-A-L-T-C-P-W-D-E-Y-L-A-W-I-A-T-L-E-A-G-S-E-A-R-R-K-M-E-G-V-P-K-Y-G-E-I-V-I-D-I-N-H-V-P-M-L-A-N-A-F-D-K-A-R-A-A-Q-T-S-Q-Q-Q-E-W-S-T-M-L-L-S-M-L-H-D-I-H-Q-E-N-A-I-Y-L-M-V-R-R-L-R-D"} +{"text": "### FUNCTION Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination ### SEQUENCE -M-N-D-T-Y-Q-P-I-N-C-D-D-Y-D-N-L-E-L-A-C-Q-H-H-L-M-L-T-L-E-L-K-D-G-E-K-L-Q-A-K-A-S-D-L-V-S-R-K-N-V-E-Y-L-V-V-E-A-A-G-E-T-R-E-L-R-L-D-K-I-T-S-F-S-H-P-E-I-G-T-V-V-V-S-E-S"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-A-R-V-T-S-V-T-L-G-E-H-L-T-G-F-V-G-E-M-I-Q-S-G-R-Y-G-N-I-S-E-V-L-R-D-A-L-R-L-M-E-A-R-E-Q-R-V-Q-H-V-R-D-M-V-L-A-G-T-N-A-P-V-S-H-R-L-M-D-E-I-F-S-A-A-V-K-D-T-S-V"} +{"text": "### FUNCTION Involved in the down-regulation of lcrGVH transcription in the presence or absence of calcium and is necessary for lcrG protein expression in the absence of calcium Plays an important role in the regulation of the low-calcium response ### SEQUENCE -M-M-E-D-P-L-I-P-W-L-T-E-H-G-L-V-C-H-P-H-T-L-S-G-T-P-I-S-L-G-S-A-F-Q-L-A-G-L-K-L-A-W-R-V-E-I-E-Q-R-R-V-W-I-V-L-I-Q-R-V-E-Q-R-R-G-L-K-N-P-F-A-A-L-Y-M-L-A-N-A-A-R-A-V-L-G-P-D-Y-Y-L-Y-G-N-V-D-V-L-A-G-S-S-L-S-T-Q-R-L-A-H-F-Y-R-R-W-T-G-A-K-E-L-S-T-G-W-F-S-L-K-V-S-Q-V-I-T-L-S-N-M-K-K-R-Q-N-N-G-F-A"} +{"text": "### FUNCTION Binds various plasma and ECM-proteins ### SEQUENCE -A-A-K-P-L-D-K-S-S-S-S-L-H-H-G-Y-S-K-V-H-V-P"} +{"text": "### FUNCTION Inhibits cGAS-STING-mediated type I IFN expression and NF-kB activation by inhibiting TBK1 and IKBKB/IKKB ### SEQUENCE -M-S-T-H-N-N-S-P-K-E-K-P-V-D-M-N-N-I-S-E-K-L-D-V-V-N-N-A-P-E-K-P-A-G-A-N-H-I-P-E-K-L-A-E-M-T-S-S-E-W-I-A-E-Y-W-K-G-I-N-R-G-N-D-V-P-C-C-C-P-R-K-M-T-S-A-D-K-K-F-S-V-F-G-K-G-Y-L-M-R-S-M-Q-K-D-D"} +{"text": "### FUNCTION Involved in viral RNA replication ### SEQUENCE -M-T-P-M-R-I-T-V-W-R-E-R-L-Q-Q-M-R-P-Q-R-K-L-L-K-Q-T-Q-Q-R-R-L-L-H-Q-L-Q-Q-R-K-L-L"} +{"text": "### FUNCTION Seems to play a role in virus replication ### SEQUENCE -M-T-P-M-R-I-T-V-W-R-K-R-L-Q-Q-M-R-P-Q-R-K-L-L-K-Q-T-Q-Q-R-R-L-L-H-Q-L-Q-Q-R-K-L-L-Q-Q-T-S-L"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-V-I-K-S-L-I-E-Q-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-G-I-I-A-G-I-I-K-F-I-K-G-L-I-E-K-F-T-G-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-N"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-N"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-N"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-N"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-N"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-N"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-N"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-N"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-N"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-Y"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-N"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-E-F-V-A-K-L-F-K-F-F-K-D-L-L-G-K-F-L-G-N-N"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection ### SEQUENCE -M-A-I-V-G-T-I-I-K-I-I-K-A-I-I-D-I-F-A-K"} +{"text": "### FUNCTION Chaperone protein which promotes assembly of the 20S proteasome ### SEQUENCE -M-E-S-L-R-I-T-D-D-L-E-N-I-D-P-N-I-R-I-E-K-H-I-D-N-F-E-D-T-R-I-Y-F-M-F-Y-I-F-K-S-Q-D-S-P-I-F-I-W-V-S-D-S-P-T-F-S-T-L-S-V-S-M-K-I-P-I-E-K-S-P-V-T-S-H-L-L-E-S-N-S-I-T-S-N-D-S-S-N-S-L-S-Q-R-I-V-I-K-F-K-V-Q-T-F-L-S-Y-S-I-S-Q-D-I-P-E-M-S-H-F-I-E-K-T-I-F-D-L-L-S-K-Y-L-K-K"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-V-R-L-F-R-N-P-I-K-C-I-F-Y-R-R-S-R-K-I-Q-E-K-K-L-R-K-S-L-K-K-L-N-F-Y-H-P-P-E-D-C-C-Q-I-Y-R-L-L-E-N-V-P-G-G-T-Y-F-I-T-E-N-M-T-N-D-L-I-M-V-V-K-D-S-V-D-K-K-I-K-S-I-K-L-Y-L-H-G-S-Y-I-K-I-H-Q-H-Y-Y-I-N-I-Y-M-Y-L-M-R-Y-T-Q-I-Y-K-Y-P-L-I-C-F-N-K-Y-Y-N-I"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-V-R-L-F-Y-N-P-I-K-Y-L-F-Y-R-R-S-C-K-K-R-L-R-K-A-L-K-K-L-N-F-Y-H-P-P-K-E-C-C-Q-I-Y-R-L-L-E-N-A-P-G-G-T-Y-F-I-T-E-N-M-T-N-E-L-I-M-I-A-K-D-P-V-D-K-K-I-K-S-V-K-L-Y-L-T-G-N-Y-I-K-I-N-Q-H-Y-Y-I-N-I-Y-M-Y-L-M-R-Y-N-Q-I-Y-K-Y-P-L-I-C-F-S-K-Y-S-K-I-L"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-V-R-L-F-H-N-P-I-K-C-L-F-Y-R-G-S-R-K-T-R-E-K-K-L-R-K-S-L-K-K-L-N-F-Y-H-P-P-G-D-C-C-Q-I-Y-R-L-L-E-N-V-P-G-G-T-Y-F-I-T-E-N-M-T-N-E-L-I-M-I-V-K-D-S-V-D-K-K-I-K-S-V-K-L-N-F-Y-G-S-Y-I-K-I-H-Q-H-Y-Y-I-N-I-Y-M-Y-L-M-R-Y-T-Q-I-Y-K-Y-P-L-I-C-F-N-K-Y-S-Y-C-N-S"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-V-R-L-F-R-N-P-I-K-C-I-F-Y-R-R-S-R-K-I-Q-E-K-K-L-R-K-S-L-K-K-L-N-F-Y-H-P-P-E-D-C-C-Q-I-Y-R-L-L-E-N-V-P-G-G-T-Y-F-I-T-E-N-M-T-N-D-L-I-M-V-V-K-D-S-V-D-K-K-I-K-S-I-K-L-Y-L-H-G-S-Y-I-K-I-H-Q-H-Y-Y-I-N-I-Y-M-Y-L-M-R-Y-T-Q-I-Y-K-Y-P-L-I-C-F-N-K-Y-Y-N-I"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-G-N-K-E-S-R-Y-L-E-M-C-S-E-E-A-W-L-N-I-P-N-I-F-K-C-I-F-I-R-K-L-F-Y-N-K-W-L-K-Y-Q-E-K-K-L-K-K-S-L-K-L-L-S-F-Y-H-P-K-K-D-F-V-G-I-R-D-M-L-Q-M-A-P-G-G-S-Y-F-I-T-D-N-M-T-E-E-F-L-M-L-V-V-K-H-P-E-D-G-S-A-E-F-T-K-L-C-L-K-G-S-C-I-V-I-D-G-Y-Y-Y-D-N-L-H-I-F-I-S-E-T-P-D-I-Y-K-Y-P-L-I-R-Y-D-R"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-G-N-K-E-S-K-Y-L-E-M-C-S-E-E-A-W-L-N-I-P-N-I-F-K-C-I-F-I-R-K-L-F-Y-N-K-W-L-K-Y-Q-E-K-N-L-E-K-R-L-K-L-L-S-F-Y-H-P-K-K-D-F-M-G-I-R-D-M-L-D-M-A-P-G-G-S-Y-F-I-T-D-N-V-T-E-E-F-L-M-L-V-V-K-H-P-E-D-G-S-A-E-F-T-K-L-C-L-K-G-G-C-I-V-I-D-G-F-Y-Y-D-D-L-H-I-F-I-T-E-N-P-N-L-Y-K-Y-P-L-I-H-Y-D-R"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-G-N-K-E-S-K-Y-L-E-M-C-S-D-E-A-W-L-N-I-P-N-V-F-K-C-I-F-I-R-K-L-F-Y-N-K-W-L-K-Y-Q-E-K-K-L-E-K-R-L-R-L-L-S-F-Y-H-A-K-K-D-F-I-G-I-R-D-M-L-Q-T-A-P-G-G-S-Y-F-I-T-D-N-I-T-E-E-F-L-M-L-V-L-K-H-P-E-D-G-S-A-E-F-T-K-L-C-L-K-G-S-C-I-M-I-D-G-Y-Y-Y-D-N-L-D-I-F-L-A-E-S-P-D-L-Y-K-Y-P-L-I-R-Y-D-R"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-G-N-K-E-S-R-Y-L-E-M-C-S-E-E-A-W-L-N-I-P-N-I-F-K-C-I-F-I-R-K-L-F-Y-N-K-W-L-K-F-Q-E-K-K-L-K-K-S-L-K-L-L-S-F-Y-H-P-K-K-D-F-V-G-I-R-D-M-L-Q-M-A-P-G-G-S-Y-F-I-T-D-N-I-T-E-E-F-L-M-L-V-V-K-H-P-E-D-G-S-A-E-F-T-K-L-C-L-K-G-S-C-I-V-I-D-G-Y-Y-Y-D-N-L-H-I-F-I-S-E-T-P-D-I-Y-K-Y-P-L-I-R-Y-D-R"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-G-N-R-L-N-G-S-Y-L-S-N-T-D-M-S-I-E-D-K-Q-N-K-Y-N-E-A-I-E-D-C-K-I-C-N-K-V-Y-I-K-Q-S-G-K-I-D-K-K-E-L-T-R-I-K-K-L-D-F-F-Y-S-Q-K-S-D-H-E-I-E-R-M-F-F-N-V-P-N-G-T-F-L-L-T-D-D-A-T-N-E-N-L-F-I-A-Q-K-D-L-E-N-G-S-L-N-I-A-K-L-E-F-K-G-K-A-L-Y-I-D-G-K-D-Y-F-S-L-E-N-Y-L-K-T-F-E-D-F-Y-K-Y-P-L-I-Y-N-K-N-E"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-G-N-H-L-D-G-S-Y-L-P-N-T-V-M-S-I-E-D-K-Q-N-T-Y-N-E-A-K-E-D-S-K-I-C-N-K-I-Y-I-K-Q-S-G-K-I-D-K-K-E-L-K-R-I-K-K-L-D-F-F-Y-S-Q-K-N-D-D-E-I-E-R-M-F-M-N-K-P-N-G-T-F-L-L-T-D-D-A-T-D-E-N-L-F-L-V-Q-K-D-L-E-N-G-S-L-N-I-A-K-L-D-F-N-G-K-A-L-Y-I-N-G-K-N-Y-F-S-L-E-N-Y-L-K-T-V-E-D-F-Y-K-Y-P-L-I-Y-D-E-N-K"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-G-N-H-L-D-G-S-Y-Q-P-N-M-V-M-S-I-E-D-K-Q-N-K-Y-N-E-A-K-E-R-S-K-V-C-N-K-V-Y-I-N-Q-S-G-K-I-D-K-K-E-L-K-R-I-K-K-L-D-F-F-Y-S-Q-K-N-D-D-E-I-E-R-M-F-F-N-M-P-N-G-T-F-L-L-T-D-D-V-T-H-E-N-I-Y-I-A-Q-K-D-L-E-N-G-S-L-N-I-A-K-L-E-F-K-G-E-A-L-Y-I-N-G-K-N-Y-F-F-L-E-N-Y-L-K-T-F-E-D-I-Y-K-Y-P-L-T-N-F-N-E-N-K"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-G-N-R-L-N-G-S-Y-L-S-N-T-D-M-S-I-E-D-E-Q-N-K-Y-N-E-A-I-E-D-C-K-I-C-N-K-V-Y-I-K-Q-S-G-K-I-D-K-K-E-L-N-R-I-K-K-L-D-F-F-Y-S-Q-K-T-D-Y-E-I-E-R-M-F-F-N-V-P-N-G-T-F-L-L-T-D-D-A-T-N-E-N-L-F-I-A-Q-K-D-L-E-N-G-S-L-N-I-A-K-L-E-F-K-G-K-A-L-Y-I-D-G-K-D-Y-F-S-L-E-N-Y-L-K-T-F-E-D-F-Y-K-Y-P-L-I-Y-N-K-N-E"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-R-F-F-S-Y-L-G-L-L-L-A-G-L-V-S-L-Q-G-F-S-T-D-N-P-L-E-E-E-L-R-Y-W-C-Q-Y-V-K-N-C-R-F-C-W-A-C-Q-D-G-L-C-K-N-K-V-L-K-D-M-P-S-V-Q-E-H-S-Y-P-M-E-H-C-M-I-H-R-Q-C-K-Y-I-R-D-G-P-I-F-Q-A-E-C-T-M-Q-T-C-D-A-T-H-L-I-N-A"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-G-F-F-S-Y-L-G-L-V-L-V-G-L-A-S-L-T-S-L-A-S-L-A-N-L-Q-D-F-S-T-D-N-P-L-E-E-E-L-R-C-W-C-Q-Y-V-K-N-C-R-F-C-W-A-C-Q-D-G-F-C-K-N-K-V-L-K-N-M-P-S-V-Q-E-H-S-Y-P-M-E-H-C-M-I-H-R-Q-C-K-Y-V-R-D-G-P-I-F-Q-V-E-C-M-M-Q-T-C-D-A-I-H-L-L-N-A"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-R-F-F-S-Y-L-G-L-L-L-A-G-L-A-S-L-A-S-L-A-G-L-V-S-L-A-N-L-Q-D-F-S-T-D-N-P-L-E-E-E-L-R-C-W-C-Q-Y-V-K-N-C-R-F-C-W-A-C-Q-D-G-F-C-K-N-K-V-L-K-N-M-P-S-V-Q-E-H-S-Y-P-M-E-H-C-M-L-H-R-Q-C-K-Y-I-R-D-G-P-I-F-Q-V-E-C-T-M-Q-T-C-D-A-I-R-L-L-N-V"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-R-F-F-S-Y-L-G-L-L-L-A-G-L-A-S-L-Q-G-F-S-T-D-N-P-L-E-E-E-L-R-C-W-C-L-Y-V-K-N-C-R-F-C-W-A-C-Q-D-G-L-C-K-N-K-V-L-K-D-M-P-P-V-Q-E-H-S-Y-P-M-E-Y-C-M-L-H-R-Q-C-K-Y-I-T-D-G-P-I-F-Q-V-E-C-T-M-Q-T-C-D-A-I-R-L-L-N-A"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-L-V-I-I-L-G-I-I-G-L-L-A-S-S-N-L-V-S-S-S-T-S-T-R-V-G-G-H-L-P-L-T-F-D-P-P-E-N-E-L-G-Y-W-C-T-Y-V-E-S-C-R-F-C-W-D-C-E-D-G-I-C-T-S-R-V-W-G-N-N-S-T-S-I-V-E-N-D-Y-V-K-Y-C-E-V-S-R-W-G-N-L-C-R-Y-D-V-E-E-H-I-Y-H-S-M-N-C-S-D-P-K-P-W-N-P-Y-K-I-A-R-K-E-W-K-K-N-E-H-P-R-K-D-L-K-K-D-E-F"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-L-V-I-I-L-G-V-I-G-L-L-A-S-S-N-L-V-S-S-S-T-S-T-R-V-G-G-H-L-P-L-T-F-D-P-P-E-N-E-L-G-Y-W-C-T-Y-V-E-S-C-R-F-C-W-D-C-E-D-G-V-C-T-S-R-I-W-G-N-N-S-T-S-I-V-E-N-S-Y-I-K-Y-C-E-V-S-R-W-G-D-Q-C-R-Y-D-V-E-E-H-I-Y-Y-T-M-N-C-S-D-P-K-P-W-N-P-Y-K-I-A-R-K-E-W-K-K-N-E-H-F-R-K-D-L-K-K-D-E-F"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-L-V-I-I-L-G-V-I-G-L-L-A-S-S-N-L-V-S-S-S-T-S-T-R-V-G-G-H-L-P-L-T-F-D-P-P-E-N-E-L-G-Y-W-Y-T-Y-V-E-S-C-R-F-C-W-D-C-E-D-G-V-C-T-S-R-V-W-G-N-N-S-T-S-I-V-E-N-D-Y-V-K-Y-C-E-V-S-R-W-G-D-Q-C-R-Y-D-V-E-E-H-I-Y-Y-T-M-N-C-S-D-P-K-P-W-N-P-Y-K-I-A-K-E-G-V-E-K-G"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-L-V-I-I-L-G-I-I-G-L-L-A-S-S-N-L-V-S-S-S-T-S-T-R-V-G-G-H-L-P-L-T-F-D-P-P-E-N-E-L-G-Y-W-C-T-Y-V-E-S-C-R-F-C-W-D-C-E-D-G-I-C-T-S-R-V-W-G-N-N-S-T-S-I-V-E-N-D-Y-V-K-Y-C-E-V-S-R-W-G-N-L-C-R-Y-D-V-E-E-H-I-Y-Y-S-M-N-C-S-D-P-K-P-W-N-P-Y-K-I-A-R-K-E-W-K-K-N-E-Y-L-R-K-D-L-K-K-D-E-F"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-K-V-L-I-L-V-L-L-G-V-V-I-L-Q-A-A-P-I-R-K-V-E-N-L-L-P-T-R-N-P-P-Q-N-E-L-V-Y-W-C-T-Y-A-N-Q-C-D-F-C-W-E-C-I-H-G-I-C-R-N-R-I-Q-A-D-W-P-V-I-H-Q-N-D-W-I-I-N-C-T-V-S-R-W-N-G-Q-C-H-Y-Y-E-G-S-Q-Q-Y-L-H-H-E-M-D-C-I-N-P-T-S-H-T-Y-P-H-T-E-Y-M-K-I-Y-E-R-D-D-L"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-K-V-L-I-L-V-L-L-G-V-V-I-L-Q-A-A-P-I-R-K-L-E-D-L-L-P-T-R-N-P-P-Q-N-E-L-V-Y-W-C-T-Y-A-N-Q-C-D-F-C-W-E-C-I-H-G-I-C-R-N-R-I-Q-A-D-W-P-V-I-H-Q-N-D-W-I-I-N-C-T-V-S-R-W-N-G-I-C-R-Y-Y-E-G-P-R-G-H-I-D-H-E-M-D-C-A-N-P-T-Y-H-T-Y-P-H-I-E-Y-M-K-I-Y-V-R-D-D-L"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-K-V-L-I-L-V-L-L-A-V-V-I-L-Q-A-A-P-I-R-K-L-E-D-L-L-P-T-R-Y-P-P-D-H-E-L-V-Y-W-C-T-Y-A-N-Q-C-D-F-C-W-E-C-V-H-G-I-C-R-N-R-I-Q-A-D-W-P-V-I-H-Q-N-D-W-I-I-N-C-T-V-S-R-W-N-G-I-C-S-Y-Y-E-G-P-R-N-H-T-D-H-Q-M-D-C-A-N-P-T-S-H-T-Y-P-H-R-E-Y-M-K-I-Y-E-R-D-D-L"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-K-V-L-I-L-V-L-L-G-V-V-I-L-Q-A-A-P-I-R-K-L-E-D-L-L-P-T-R-Y-P-P-E-H-E-L-V-Y-W-C-T-Y-A-N-Q-C-D-F-C-W-E-C-V-H-G-I-C-R-N-R-I-Q-A-D-W-P-V-I-H-Q-N-D-W-I-I-N-C-T-V-S-R-W-N-G-I-C-S-Y-Y-E-G-P-R-N-H-T-D-H-Q-M-D-C-A-N-P-T-S-H-T-Y-P-H-R-E-Y-M-K-I-Y-E-R-D-D-L"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-K-V-L-L-G-L-L-L-G-Y-S-V-L-I-H-A-Y-E-L-P-D-L-P-R-T-Q-H-P-P-K-S-E-L-S-Y-W-C-T-Y-V-P-Q-C-D-F-C-W-D-C-Q-D-G-I-C-K-N-K-I-T-G-S-R-F-I-N-S-N-H-S-I-V-N-C-R-V-F-R-D-S-K-T-Q-S-C-L-Y-E-I-S-S-K-M-P-N-H-F-N-M-E-C-S-H-P-R-P-Y-T-G-N-E-I-F-M-K-P-W-G-G-G"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-K-V-L-L-E-L-L-L-G-Y-S-V-H-I-L-A-H-E-L-P-D-L-P-R-T-Q-H-P-P-K-S-E-L-S-Y-W-C-T-Y-V-P-Q-C-D-F-C-W-D-C-Q-D-G-I-C-K-N-K-I-T-E-S-H-F-I-D-S-N-H-S-I-V-N-C-R-V-F-R-D-S-K-T-Q-S-C-L-Y-E-I-S-S-K-M-P-N-H-F-S-M-E-C-L-H-P-R-P-Y-T-G-N-E-I-F-M-Q-T-W-G-G-G-V-T-I-N-N-Y-L"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-I-T-L-Y-E-A-A-I-K-T-L-I-T-H-R-K-Q-I-L-K-H-P-D-S-R-E-I-L-L-A-L-G-L-Y-W-D-K-T-H-I-L-L-K-C-H-E-C-G-K-M-S-L-T-G-K-H-S-T-K-C-I-N-I-N-C-L-L-I-L-A-I-K-K-K-N-K-R-M-V-D-T-L-I-R-M-G-A-D-V-T-Y-I-H-L-L-K-N-K-I-K-L-S-Y-N-Q-L-S-M-L-K-S-N-S-Q-I-A-L-K-E-L-H-A-I-C-Y-L-L-Y-G-R-L-P-K-K-I-K-Q-G-M-Q-L-C-K-T-M-A-G-L-C-G-E-L-L-C-A-F-L-A-P"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-I-T-L-Y-E-A-A-I-K-T-L-I-T-H-R-K-Q-I-L-K-H-P-D-S-R-E-I-L-L-A-L-G-L-Y-W-N-K-T-H-I-L-L-K-C-H-E-C-G-K-I-S-L-T-G-K-H-S-T-K-C-I-N-I-N-C-L-L-I-L-A-I-K-K-K-N-K-R-M-V-D-T-L-I-G-M-G-A-D-V-T-Y-I-H-F-L-K-N-K-T-K-L-S-Y-N-Q-L-S-A-L-K-S-N-S-Q-I-S-L-K-E-F-R-A-I-C-Y-I-L-Y-S-R-L-P-K-K-I-K-Q-G-I-R-L-C-K-T-M-A-G-L-C-G-E-L-L-C-A-F-F-A-P"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-I-T-L-Y-E-A-A-I-K-T-L-I-T-H-R-K-Q-I-L-K-H-P-D-S-R-E-I-L-L-A-L-G-L-Y-W-D-K-T-H-I-L-L-K-C-Q-E-C-G-K-I-S-L-T-G-K-H-S-T-K-C-I-N-I-N-C-L-L-I-L-A-I-K-K-K-N-K-R-I-V-D-T-L-I-G-M-G-A-D-V-K-Y-I-H-F-L-N-N-K-T-K-L-S-Y-N-Q-L-S-M-L-K-S-N-P-Q-I-S-L-K-E-F-H-A-I-C-Y-I-L-Y-G-R-L-P-K-K-I-K-Q-G-M-R-L-C-K-T-L-A-G-L-C-G-E-L-L-C-A-F-F-A-P"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-I-T-L-Y-E-A-A-I-K-T-L-I-T-H-R-K-Q-I-L-K-H-P-D-S-R-E-I-L-L-A-L-G-L-Y-W-D-K-T-H-I-L-V-K-C-R-E-C-G-K-M-S-L-T-G-K-H-S-T-K-C-I-N-I-N-C-L-L-I-L-A-I-K-K-K-N-K-R-M-V-D-T-L-I-R-M-G-A-D-V-T-Y-I-H-L-L-K-N-K-I-K-L-S-Y-N-Q-L-S-M-L-K-S-N-S-Q-I-S-L-K-E-L-H-A-I-C-Y-L-L-Y-G-R-L-P-K-K-I-K-Q-G-M-Q-L-C-K-T-M-A-G-L-C-G-E-L-L-C-A-F-L-A-P"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-K-N-F-F-Y-K-G-N-K-K-I-Q-Q-R-M-L-N-Y-G-M-E-W-A-A-T-H-G-K-V-R-T-F-I-C-C-Y-T-L-G-G-T-A-S-L-K-L-Y-Q-K-A-Y-Q-N-E-K-F-M-I-M-A-L-C-S-Y-L-G-N-I-Q-I-N-N-P-W-E-S-L-N-P-Y-T-M-V-Q-N-K-E-K-F-L-P-L-K-F-S-E-E-T-Q-Y-F-Y-I"} +{"text": "### FUNCTION Makes mgtA transcription sensitive to intracellular proline levels Under low levels of proline this protein cannot be fully translated, and a stem loop forms which permits transcription of the downstream mgtA gene ### SEQUENCE -M-D-P-E-P-T-P-L-P-R-W-R-I-F-L-F-R"} +{"text": "### FUNCTION Oxygen-regulated protein required for bacterial internalization ### SEQUENCE -M-I-R-R-N-R-Q-M-N-R-Q-P-L-P-I-I-W-Q-R-I-I-F-D-P-L-S-Y-I-H-P-Q-R-L-Q-I-A-P-E-M-I-V-R-P-A-A-R-A-A-A-N-E-L-I-L-A-A-W-R-L-K-N-G-E-K-E-C-I-Q-N-S-L-T-Q-L-W-L-R-Q-W-R-R-L-P-Q-V-A-Y-L-L-G-C-H-K-L-R-A-D-L-A-R-Q-G-A-L-L-G-L-P-D-W-A-Q-A-F-L-A-M-H-Q-G-T-S-L-S-V-C-N-K-A-P-N-H-R-F-L-L-S-V-G-Y-A-Q-L-N-A-L-N-E-F-L-P-E-S-L-A-Q-R-F-P-L-L-F-P-P-F-I-E-E-A-L-K-Q-D-A-V-E-M-S-I-L-L-L-A-L-Q-Y-A-Q-K-Y-P-N-T-V-P-A-F-A-C"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-T-T-Y-Y-Y-V-L-L-S-V-T-T-W-V-G-L-R-H-E-A-K-R-E-L-V-Y-R-G-R-R-S-I-G-R-M-P-R-E-W-A-C-R-R-S-R-R-F-A-A-N-G-V-D-A-A-R"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to cognate MazF2 toxin and counteracts its endoribonuclease activity ### SEQUENCE -M-K-T-A-I-S-L-P-D-E-T-F-D-R-V-S-R-R-A-S-E-L-G-M-S-R-S-E-F-F-T-K-A-A-Q-R-Y-L-H-E-L-D-A-Q-L-L-T-G-Q-I-D-R-A-L-E-S-I-H-G-T-D-E-A-E-A-L-A-V-A-N-A-Y-R-V-L-E-T-M-D-D-E-W"} +{"text": "### FUNCTION Binds to decorin which may mediate the adherence of Bburgdorferi to collagen fibers in skin and other tissues ### SEQUENCE -M-K-I-G-K-L-N-S-I-V-I-A-L-F-F-K-L-L-V-A-C-S-I-G-L-V-E-R-T-N-A-A-L-E-S-S-S-K-D-L-K-N-K-I-L-K-I-K-K-E-A-T-G-K-G-V-L-F-E-A-F-T-G-L-K-T-G-S-K-V-T-S-G-G-L-A-L-R-E-A-K-V-Q-A-I-V-E-T-G-K-F-L-K-I-I-E-E-E-A-L-K-L-K-E-T-G-N-S-G-Q-F-L-A-M-F-D-L-M-L-E-V-V-E-S-L-E-D-V-G-I-I-G-L-K-A-R-V-L-E-E-S-K-N-N-P-I-N-T-A-E-R-L-L-A-A-K-A-Q-I-E-N-Q-L-K-V-V-K-E-K-Q-N-I-E-N-G-G-E-K-K-N-N-K-S-K-K-K-K"} +{"text": "### FUNCTION Antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC1 ### SEQUENCE -M-A-T-I-Q-V-R-D-L-P-E-D-V-A-E-T-Y-R-R-R-A-T-A-A-G-Q-S-L-Q-T-Y-M-R-T-K-L-I-E-G-V-R-G-R-D-K-A-E-A-I-E-I-L-E-Q-A-L-A-S-T-A-S-P-G-I-S-R-E-T-I-E-A-S-R-R-E-L-R-G-G"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC16 ### SEQUENCE -M-A-L-W-Y-Q-A-M-I-A-K-F-G-E-Q-V-V-D-A-K-V-W-A-P-A-K-R-V-G-V-H-E-A-K-T-R-L-S-E-L-L-R-L-V-Y-G-G-Q-R-L-R-L-P-A-A-A-S-R"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC23 ### SEQUENCE -M-L-S-D-E-E-R-E-A-F-R-Q-Q-A-A-A-Q-Q-M-S-L-S-N-W-L-R-Q-A-G-L-R-Q-L-E-A-Q-R-Q-R-P-L-R-T-A-Q-E-L-R-E-F-F-A-S-R-P-D-E-T-G-A-E-P-D-W-Q-A-H-L-Q-V-M-A-E-S-R-R-R-G-L-P-A-P"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-I-S-A-K-S-K-T-K-R-I-T-I-T-F-E-I-P-E-D-I-D-A-K-K-F-K-D-D-V-K-R-Y-V-R-Y-K-L-L-A-N-K-L-Y-E-L-L-E-G-E-N-I-E-E-I-E-E-E-I-R-K-R-R-E"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-Q-L-L-Y-D-L-T-K-M-N-Y-S-A-L-Y-G-E-G-R-Y-L-R-I-P-A-P-I-H-Y-A-D-K-F-V-K-A-L-G-K-N-W-K-I-D-E-E-L-L-K-H-G-F-L-Y-F-I"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-Q-G-P-V-I-I-P-L-I-S-T-L-G-L-S-F-L-A-I-L-L-A-Y-K-I-S-F-S-V-I-G-F-I-N-S-T-L-P-T-T-L-F-P-S-K-P-Y-M-L-F-V-K-I-S-T-I-S-P-L-T-C-P-S-L-I-I-L-T-P-A-L-T-W-S-L-T-A-L-S-M-A-Y-L-Y-S-S-Y-K-P-N-T-F-F-T-L-S-K-N-V-S-S-F-L-T-T-G"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-S-I-V-Q-S-Y-I-T-D-E-K-G-N-I-K-G-V-I-L-D-Y-K-T-F-K-K-I-E-E-L-L-L-D-Y-G-L-L-K-A-M-E-E-V-E-N-E-E-E-I-D-L-E-T-A-K-K-L-L-E-Q"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-P-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-Q-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-K-Q-T-N-N-L-I-T-E-R-T-H-P-C-H-K-P-M-R-H-T-S-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-P-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-Q-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-K-Q-T-N-N-L-I-T-E-R-T-H-P-C-H-K-P-M-R-H-T-S-H"} +{"text": "### FUNCTION Might take part in the signal recognition particle ### SEQUENCE -M-N-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle ### SEQUENCE -M-N-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-A-G-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-A-E-K-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-A-G-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-A-E-K-A"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-S-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-H-L-E-H-E-T-A-A-K-N-P-S-K-Q-R-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Might be involved in the expression of prgA, but is not required for activation of the expression of prgB ### SEQUENCE -M-T-K-K-E-Q-S-I-W-R-K-E-M-L-A-L-M-N-E-D-A-D-W-Y-R-N-E-D-T-E-R-F-K-R-I-Q-E-L-A-K-K-I-E-T-A-S-T-R-Q-F-S-S-H-I-S-K-E-R-F-E-A-Y-Q-R-M-G-L-Q-F-K-E-I-A-E-E-F-H-I-T-T-T-A-L-Q-Q-W-R-K-D-N-G-Y-P-I-Y-N-K-N-N-R-K"} +{"text": "### FUNCTION Pathogenicity determinant May act as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing , a mechanism of plant viral defense that limits the accumulation of viral RNAs ### SEQUENCE -M-R-L-F-S-S-K-V-N-S-S-A-Q-I-K-D-C-S-T-W-Y-P-Q-P-G-Q-H-I-S-I-R-T-F-R-E-L-N-Q-V-P-T-S-K-N-T-S-T-K-M-E-S-Q-S-N-G-D-N-S-K-S-T-A-D-L-Q-E-E-V-S-S-L-P-T-T-H-T-Q-R-H"} +{"text": "### FUNCTION May be required for viral persistance in the host ### SEQUENCE -M-D-T-Q-M-C-A-L-F-A-Q-P-L-T-L-L-P-D-L-N-I-C-S-W-Q-T-V-N-G-S-Q-R-T-F-F-V-W-T-W-T-M-T-S-S-G-L-R-T-R-A-I-N-L-K-Q-W-N-G-L-T-Y-R-S-Y-A-I-L-S-W-N-P-R-E-T-P-L-H-L-T-R-V-T-P-S-P-Q-V-T-K-G-S-L-S-T-T-S-I-P-I-N-T-K-I-Q-L-I-C-L-P-A-V-A-M-L-A-T-P-P-K-T-T-D-N-C-R-T-S-W-A-A-L-Q-M-L-L-L-L-W-H-L-S-S-W-I-K-T-Q-R-R-W-R-I-S-L-T-E"} +{"text": "### FUNCTION May have antimicrobial properties, like most ant linear peptides ### SEQUENCE -G-K-E-K-D-V-F-M-D-K-L-R-D-A-G-A-A-G-I-D-Y-L-K-H-F-T-H-H-I-V-K-K-K-N"} +{"text": "### FUNCTION May play a role in host modulation ### SEQUENCE -M-L-L-L-Q-I-L-F-A-L-L-Q-R-Y-R-Y-K-P-H-S-L-S-D-G-L-L-L-A-L-H-F-L-L-F-F-R-A-L-P-K-S"} +{"text": "### FUNCTION Precursors of the cornified envelope of the stratum corneum ### SEQUENCE -M-S-Y-Q-K-H-Q-Q-K-W-Q-L-P-A-K-C-L-P-K-Y-P-S-K-W-T-P-Q-A-P-A-S-C-P-A-P-C-P-P-P-A-P-S-C-C-V-S-S-C-C-I-S-G-F-G-G-H-C-S-L-V-S-L-R-F-P-R-F-Y-L-R-Q-P-Q-H-S-D-C-C-E-H-E-S-S-R-C-S-T-C-Y-S-S-G-D-C-S"} +{"text": "### FUNCTION Possibly involved in pGI2 replication mechanism ### SEQUENCE -M-M-A-I-F-I-S-I-V-L-V-V-S-F-V-L-F-N-R-V-Q-A-K-K-S-I-Y-N-Y-I-A-R-Q-G-I-Q-E-S-Q-L-K-Y-I-D-F-H-K-D-F-K-M-G-G-Y-W-L-A-V-Y-V-E-G-E-N-P-D-I-Y-Y-E-Y-S-Y-Q-D-K-K-V-N-F-Q-A-Y-F-N-S-E-K-A-I-K-K-K-M-W-G-G-S-G-L-T-E-I-E-M-K-K-L-K-Y-P-P-L-Q"} +{"text": "### FUNCTION In contrast to PsiB protein of plasmid R6-5, this protein is unable to prevent SOS induction for potentially two reasons less activity and/or insufficient expression ### SEQUENCE -M-K-T-E-L-T-L-N-V-L-Q-T-M-N-A-Q-E-Y-E-D-I-R-A-A-G-S-D-E-R-R-E-L-T-H-A-V-M-R-E-L-D-A-P-D-N-W-T-M-N-G-E-Y-G-S-E-F-G-G-F-F-P-V-Q-V-R-F-T-P-A-H-E-R-F-H-L-A-L-C-S-P-G-D-V-S-Q-V-W-V-L-V-L-V-N-A-G-G-E-P-F-A-V-V-Q-V-Q-R-R-F-A-S-E-A-V-S-H-S-L-A-L-A-A-S-L-D-T-Q-G-Y-S-V-N-D-I-I-H-I-S-M-A-E-G-G-Q-V"} +{"text": "### FUNCTION Inhibition of the induction of the SOS pathway ### SEQUENCE -M-K-T-E-L-T-L-N-V-L-Q-T-M-S-A-Q-E-Y-E-D-I-R-A-A-G-S-D-E-R-R-E-L-T-H-A-V-M-R-E-L-D-A-P-D-N-W-T-M-N-G-E-Y-G-S-E-F-G-G-F-F-P-V-Q-V-R-F-T-P-A-H-E-R-F-H-L-A-L-C-S-P-G-D-V-S-Q-V-W-V-L-V-L-V-N-A-G-G-E-P-F-A-V-V-Q-V-Q-R-R-F-A-P-E-A-V-S-H-S-L-A-L-A-A-S-L-D-A-Q-G-Y-S-V-S-D-I-I-H-I-L-M-A-E-G-G-Q-A"} +{"text": "### FUNCTION Repressor of the ant/reb gene ### SEQUENCE -M-L-V-R-T-T-A-D-F-R-Y-C-G-I-F-V-S-V-N-R-V-T-P-E-L-W-W-G-V-M-G-R-L-R-P-A-G-F-T-N-A-S-L-S-T-L-S-R-P-A-T-C-L-T-A-G-S-R-L-L-N-L-L-V-R-P"} +{"text": "### FUNCTION Modulates the activity of the host recBCD nuclease And thus protects linear double-stranded DNA from exonuclease degradation ### SEQUENCE -M-R-R-L-N-I-T-T-A-E-M-E-S-V-C-G-R-M-V-A-C-R-A-A-E-H-L-G-L-N-I-N-Q-F-Y-Y-I-A-K-K-L-S-L-K-T-A-F-I-K-P-R-W-S-D-D-E-D-K-R-M-Q-T-L-I-S-S-G-Y-T-Q-R-N-V-A-K-I-L-G-R-S-E-E-S-V-K-S-R-L-S-R-L-R-K-K"} +{"text": "### FUNCTION Modulates the activity of the host recBCD nuclease And thus protects linear double-stranded DNA from exonuclease degradation ### SEQUENCE -M-P-A-P-L-Y-G-A-D-D-P-R-R-C-S-G-N-S-V-S-E-V-L-D-K-F-R-K-N-Y-D-L-I-M-S-L-P-Q-E-T-K-E-E-K-E-F-R-H-C-I-W-L-A-E-K-E-E-R-E-R-I-Y-Q-T-A-I-R-P-F-R-K-A-T-Y-T-K-F-I-E-I-D-P-R-L-R-D-Y-R-S-R-Y-G-A-I-S-N-N"} +{"text": "### FUNCTION E3 proteins seem to be dispensable for virus growth in tissue culture cells They are potentially important for virus growth under special conditions ### SEQUENCE -M-K-A-F-A-V-L-F-V-L-S-L-I-K-T-E-L-R-P-S-Y-G-L-P-L-L-Q-S-G-L-Y-N-T-N-Q-I-F-Q-K-T-Q-T-L-P-P-F-I-Q-D-S-N-S-T-L-P-A-P-S-T-T-N-L-P-E-T-N-K-L-A-S-H-L-Q-H-R-L-S-R-S-L-L-S-A-N-T-T-T-P-K-T-G-G-E-L-R-G-L-P-T-D-D-P-W-V-V-A-G-F-V-T-L-G-V-V-A-G-G-L-V-L-I-L-C-Y-L-Y-T-P-C-C-A-Y-L-V-I-L-C-C-W-F-K-K-W-G-P-Y"} +{"text": "### FUNCTION Participates in the assembly of the viral procapsid in the cytoplasm Released from the procapsid upon genome packaging, possibly through affinity displacement by the protein ORF8, or by proteolysis ### SEQUENCE -M-K-I-Y-T-Q-R-N-N-K-V-E-F-S-D-S-G-S-S-E-Y-S-E-Y-Q-R-V-I-D-A-D-T-K-E-N-T-Y-E-I-V-A-T-Y-N-R-Y-D-E-I-Q-E-A-G-E-G-T-D-L-R-S-M-L-D-K-Y-G-D-D-Y-L-E-L-L-P-P-A-R-L-G-G-D-D-T-I-L-P-K-S-V-L-E-L-E-N-I-R-L-Q-N-T-E-Y-L-S-L-L-E-N-I-N-S-K-L-D-K-Q-G-L-G-D-L-D-N-F-I-K-N-W-Q-E-S-Q-K-K-I-E-N-E-K-G-K-K-E-D-E-K-E-N-E"} +{"text": "### FUNCTION Plays a central role in the packaging of viral DNA into phage procapsid, which occurs in the late stage of infection Can interact with the replicative complex after the completion of one round of DNA synthesis When protein ORF5 is bound to the replicative form, the complex becomes accessible to procapsid and serves as a DNA packaging apparatus ### SEQUENCE -M-D-K-L-I-S-L-K-D-V-M-R-F-I-F-K-F-G-L-P-G-L-C-I-A-V-G-L-I-V-M-V-A-N-K-W-L-G-I-P-W-P-C-Y-V-I-V-G-S-V-S-L-S-F-G-L-I-L-F-I-V-Q-T-I-K-E-I-I-I-Y-R-K-E-K-K-D-E-N-I-Y-S-K-K"} +{"text": "### FUNCTION Component of the cuticle of migratory locust which contains more than 100 different structural proteins ### SEQUENCE -G-L-L-G-L-G-Y-G-G-Y"} +{"text": "### FUNCTION Component of the cuticle of migratory locust which contains more than 100 different structural proteins ### SEQUENCE -G-G-P-A-A-Y-S-X-Y-X-N-G-A-D-F-G-A-V-G-E-X-L-G-S-X-S-K-G-L"} +{"text": "### FUNCTION Positively regulates late transcription from 2 promoters in P4 and 4 promoters in P2 ### SEQUENCE -M-I-Y-C-P-S-C-G-H-V-A-H-T-R-R-A-H-F-M-D-D-G-T-K-I-M-I-A-Q-C-R-N-I-Y-C-S-A-T-F-E-A-S-E-S-F-F-S-D-S-K-D-S-G-M-E-Y-I-S-G-K-Q-R-Y-R-D-S-L-T-S-A-S-C-G-M-K-R-P-K-R-M-L-V-T-G-Y-C-C-R-R-C-K-G-L-A-L-S-R-T-S-R-R-L-S-Q-E-V-T-E-R-F-Y-V-C-T-D-P-G-C-G-L-V-F-K-T-L-Q-T-I-N-R-F-I-V-R-P-V-T-P-D-E-L-A-E-R-L-H-E-K-Q-E-L-P-P-V-R-L-K-T-Q-S-Y-S-L-R-L-E"} +{"text": "### FUNCTION This protein kills Ecoli when the beta protein is absent ### SEQUENCE -M-L-N-H-V-Y-G-L-I-G-V-V-G-T-I-I-T-I-A-T-S-F-I-R-N-Q-D-I-S-Q-W-L-L-V-C-S-G-W-L-A-A-L-L-I-G-W-F-T-H-R-T-I-K-A-I-S-N-N-H-T-N-V-I-K-S-N-M-E-V-I-N-S-H-N-E-S-N-Q-N-L-M-A-E-N-K-E-L-I-K-E-L-A-R-T-S-E-Q-K-E-K-M-E-S-I-A-A-Y-L-A-T-Q-N-P-Q-I-N-A-M-P-R-T-A-S-R-P-E-N-I-D-S-E-A-N"} +{"text": "### FUNCTION Involved in the conjugative transfer of the hemolysin plasmid pAD1 ### SEQUENCE -L-F-S-L-V-L-A-G"} +{"text": "### FUNCTION cPD1 is involved in the conjugative transfer of the bacteriocin plasmid pPD1 ### SEQUENCE -F-L-V-M-F-L-S-G"} +{"text": "### FUNCTION This protein is essential to promote the specific transfer of the plasmid in the presence of conjugative plasmids ### SEQUENCE -M-T-E-L-E-T-H-L-L-N-A-L-E-Q-L-Q-Q-D-Y-M-Q-R-L-S-E-W-E-S-A-F-V-E-L-Q-K-M-F-S-L-T-Q-R-D-N-A-M-L-N-E-R-V-M-Q-L-S-Q-Q-V-Q-H-L-S-E-Q-T-E-R-L-S-Q-L-Y-S-E-N-W-R"} +{"text": "### FUNCTION May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism ### SEQUENCE -M-A-K-Q-I-I-V-T-D-S-T-S-D-L-S-H-E-Y-L-K-Q-H-N-I-H-V-I-P-L-S-L-T-I-D-G-K-S-Y-T-D-Q-A-D-I-S-S-S-E-Y-I-D-H-I-E-N-D-A-D-V-K-T-S-Q-P-P-I-G-R-F-I-E-T-Y-E-Q-L-A-Q-D-D-V-E-I-I-S-I-H-L-S-S-G-L-S-G-T-Y-N-T-A-V-Q-A-S-H-M-V-D-G-N-I-T-V-I-D-S-K-S-I-S-F-G-L-G-Y-Q-I-K-Q-I-V-E-L-V-L-L-Q-S-K-K-I"} +{"text": "### FUNCTION In the absence of gp17, P22 is sensitive to a superinfection exclusion system of the fel-2 prophage ### SEQUENCE -M-K-L-R-V-W-H-I-P-Q-V-P-M-K-P-F-I-V-E-V-G-S-V-E-E-G-V-R-M-M-D-A-L-A-D-Y-D-A-F-Q-Y-D-N-N-I-K-P-D-Y-C-N-A-N-G-L-Q-M-F-D-E-S-L-T-D-Q-D-L-E-D-M-E-L-D-D-R-W-I-D-W-Y-S-E-C-Q-C-Y-D-D-P-R-E-Y-L-E-S-L-K-E-E-T-T-A-A"} +{"text": "### FUNCTION P22 kil is essential for lytic growth in the absence of abc Expression of P22 kil causes filamentation and cell death ### SEQUENCE -M-T-I-V-P-V-N-G-T-I-L-V-Q-Q-G-N-R-E-F-N-K-L-Y-E-A-S-F-P-D-T-K-E-G-N-S-A-A-Y-A-W-A-S-S-I-A-M-G-W-E-D-C-Q-D-E-D-W-N-R-N-H-A-A"} +{"text": "### FUNCTION Arf may be recombination-related ### SEQUENCE -M-Q-H-E-F-S-D-E-E-F-I-A-L-I-S-P-E-I-E-E-E-V-E-Q-Q-I-N-L-A-A-E-R-Q-N-P-I-I-G-W-D-E-F-A-G-Y-Y-S"} +{"text": "### FUNCTION May control expression of its associated restriction-modification system SmaI ### SEQUENCE -M-P-D-A-D-I-C-F-M-D-I-K-E-I-L-A-E-N-V-R-S-Y-R-N-I-N-N-L-S-Q-E-Q-L-A-E-I-S-G-L-H-R-T-Y-I-G-S-V-E-R-K-E-R-N-V-T-L-S-T-L-I-I-L-A-K-A-L-N-T-S-V-P-K-L-L-T-R-Q-G-L-K-N-E-Q-G"} +{"text": "### FUNCTION This protein is probably required for relaxation complex formation ### SEQUENCE -M-S-D-E-I-K-Q-I-A-A-L-I-G-H-H-Q-A-L-E-K-R-V-T-S-L-T-E-Q-F-Q-A-A-S-S-Q-L-Q-Q-Q-S-E-T-L-S-R-V-I-R-E-L-D-S-A-S-G-N-M-T-D-T-V-R-K-S-V-S-S-A-L-T-Q-V-E-K-E-L-K-Q-A-G-L-A-Q-Q-K-P-A-T-E-A-L-N-Q-A-A-D-T-A-K-A-M-I-H-E-M-R-R-E-M-S-R-Y-T-W-K-S-A-I-Y-L-V-L-T-I-F-F-V-L-A-S-C-V-T-A-F-T-W-F-M-N-D-G-Y-S-Q-I-A-E-M-Q-R-M-E-A-V-W-Q-K-K-A-P-L-A-D-I-S-R-C-D-G-K-P-C-V-K-V-D-T-R-T-T-Y-G-D-K-E-N-T-W-M-I-I-K-K"} +{"text": "### FUNCTION Involved in surface exclusion ### SEQUENCE -M-K-R-S-D-L-E-K-D-A-A-Y-I-L-D-K-F-K-Q-L-D-Y-E-I-P-S-N-R-Q-I-L-K-V-I-F-Y-K-L-V-V-V-Y-V-F-Q-L-L-F-I-I-F-D-I-F-I-N-S-N-V-R-D-Y-H-Y-F-D-T-F-V-I-T-L-G-S-N-A-F-F-S-L-V-F-L-M-S-T-Y-N-L-V-S-L-K-I-S-L-G-S-E-I-T-E-Q-S-V-L-L-K-L-V-E-R-K-I-N-S-Y-G-Q-F-L-M-V-V-N-A-I-V-G-C-V-L-L-S-S-G-E-R-F-V-A-G-L-G-F-S-W-F-V-T-Y-L-I-S-M-I-T-L-Q-T-S-L-S-R-Y-M-T-P-A-V-V-S-S-L-S-K-V-K-E-L-L-S-A-S-P-K"} +{"text": "### FUNCTION May be involved in activation of synthesis of the CI protein ### SEQUENCE -M-S-A-L-I-I-N-E-Y-R-E-Q-G-G-T-A-I-S-F-P-E-D-I-S-R-A-R-Q-K-L-F-R-F-L-D-N-R-F-D-S-D-Q-Y-R-E-N-V-R-E-L-T-P-A-I-M-A-V-L-P-V-E-F-R-T-R-L-A-P-Q-N-D-T-M-S-L-I-A-S-A-M-K-E-C-S-E-A-K-Q-A-V-L-L-N-A-P-E-H-Q-K-M-K-E-V-S-E-G-I-A-S-L-F-R-L-M-P-E-Q-V-G-P-L-M-T-M-V-T-S-M-L-G-V-I"} +{"text": "### FUNCTION This protein causes filamentation ### SEQUENCE -M-L-K-S-E-P-S-F-A-S-L-L-V-K-Q-S-P-G-M-H-Y-G-H-G-W-I-A-G-K-D-G-K-R-W-H-P-C-R-S-Q-S-E-L-L-K-G-L-K-T-K-S-P-K-S-S-G-F-L-I-I-R-I-V-H-F-V-I-K-G-V-K-H-V-T-R"} +{"text": "### FUNCTION Protects DNA against thermal denaturation and modulates transcription ### SEQUENCE -A-E-T-R-N-F-A-L-R-D-K-K-G-N-E-I-G-V-F-T-G-K-Q-P-R-Q-A-A-L-K-A-A-N-R-G-H-K-D-I-R-L-R-E-R-G-T-K-K-V-H-I-F-A-G-E-R-V-K-V-K-K-P-K-G-A-P-A-W-M-P-N-E-I-W-K-P-K-V-K-K-I-G-V-E-K-L-D-E-I"} +{"text": "### FUNCTION Protects DNA against thermal denaturation and modulates transcription ### SEQUENCE -A-E-M-R-N-F-A-L-R-D-A-Q-G-N-E-I-G-V-F-T-G-K-S-P-R-Q-A-A-L-K-A-A-N-R-G-Y-T-E-I-K-L-R-E-R-G-T-K-K-V-H-I-F-S-G-E-R-V-Q-V-D-K-P-A-G-A-P-A-W-M-P-D-K-I-W-K-P-K-V-K-K-E-G-I-E-K-L-D"} +{"text": "### FUNCTION Protects DNA against thermal denaturation and modulates transcription ### SEQUENCE -M-I-E-K-R-N-F-A-L-R-D-K-E-G-N-E-I-G-V-F-S-G-K-Q-P-R-Q-A-A-L-K-A-A-N-R-G-F-T-D-I-R-L-R-E-R-G-T-K-K-V-H-I-F-Q-G-E-R-I-Q-V-P-K-P-S-N-A-P-K-W-M-P-A-N-I-W-K-P-N-V-K-K-L-G-V-E-K-L-E-D-I"} +{"text": "### FUNCTION S-crystallins are structural components of squids and octopi eye lens Contains relatively little if any GST activity ### SEQUENCE -P-A-P-N-Y-T-L-Y-Y-F-N-G-R-G-R-A-E-I-L-R-M-L-F-A-A-A-G-Q-K-F-N-D-K-X-X-E-F-N"} +{"text": "### FUNCTION Plays a role in transcriptional regulation of late T4 genes Modulates the phosphorylation status of host heat shock sigma factor rpoH which is an initiation factor that promotes the attachment of host RNA polymerase to specific initiation sites ### SEQUENCE -M-E-A-I-L-F-E-M-S-I-N-S-I-S-M-A-F-V-K-D-V-P-I-T-V-A-V-M-I-D-K-R-Y-D-N-N-M-Y-L-V-E-D-F-I-S-M-P-I-P-E-D-V-E-I-K-L-K-K-I-G-I-I-E-T-V-Q-N-S-P-F-M-A-I-Q-A-F-T-K-S-N-Y-I-D-V-A-E-A-Y-Y-N-N-K-P-L-S-F-Y-S-Y-D-S-I-Y-D-W-K-I-D-K-G-N-K-F-I-I-T-D-E-S-A-L-S-Y-F-I-T-S-L-W-N-N-L-N-P-N-L-L-K-I-H-K-F-D-D-A-P-T-I-V-L-G-K-T-N-E-S-S-E-E-D-A"} +{"text": "### FUNCTION FS800 is likely to have some function in the production or maintenance of the schistosome egg It may have a function unrelated to eggshell formation ### SEQUENCE -M-I-I-I-I-K-I-R-I-N-I-H-I-I-I-L-T-I-I-I-I-K-G-T-I-N-L-R-M-S-I-V-N-Q-N-K-I-H-I-T-K-K-Q-G-I-I-M-M-M-M-M-M-M-K-I-L-K-E-I-K-N-L-F-D-L-D-I-M-V-I-H-I-G-M-I-K-F-N-L-V-E-I-V-Q-K-V-A-V-I-Q-K-V-H-I-S-H-Y-I-L-E-Q-I-D-M-V-D-E-M-I-I-H-D-F-K-H-V-D-D-P-M-V-I-V-K-I-C-F-L-T-F-L-M"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-R-F-F-S-Y-L-G-L-L-L-A-G-L-T-S-L-Q-G-F-S-T-D-N-L-L-E-E-E-L-R-Y-W-C-Q-Y-V-K-N-C-R-F-C-W-T-C-Q-D-G-L-C-K-N-K-V-L-K-D-M-S-S-V-Q-E-H-S-Y-P-M-E-H-C-M-I-H-R-Q-C-K-Y-I-R-D-G-P-I-F-Q-V-E-C-T-M-Q-T-S-D-A-T-H-L-I-N-A"} +{"text": "### FUNCTION Gene kil kills the host upon prophage induction ### SEQUENCE -M-R-N-E-I-A-I-N-H-Q-M-L-R-A-A-Q-N-K-A-V-I-A-R-F-I-G-D-S-K-M-W-L-E-A-N-K-A-M-K-S-A-I-N-L-P-W-Y-R-R-K"} +{"text": "### FUNCTION Inhibits angiotensin-converting enzyme ### SEQUENCE -P-T-H-I-K-W-G-D"} +{"text": "### FUNCTION Plays a central role in the packaging of viral DNA into phage procapsid, which occurs in the late stage of infection Can interact with the replicative complex after the completion of one round of DNA synthesis When protein ORF5 is bound to the replicative form, the complex becomes accessible to procapsid and serves as a DNA packaging apparatus ### SEQUENCE -M-H-M-F-Y-Y-S-I-Y-D-R-K-A-R-S-Y-G-D-L-I-S-F-P-S-G-E-K-E-A-A-I-R-W-F-R-D-V-V-M-D-S-D-S-K-N-I-L-H-R-Y-P-E-D-F-D-F-C-Y-I-G-Y-F-D-K-D-K-G-R-F-Y-P-V-D-A-G-I-V-T-I-I-N-A-G-E-F-F-L-D-S-E-Y-R-Q-E-E-V"} +{"text": "### FUNCTION Participates in the assembly of the viral procapsid in the cytoplasm Released from the procapsid upon genome packaging, possibly through affinity displacement by the protein ORF8, or by proteolysis ### SEQUENCE -M-K-F-R-T-I-Y-D-E-E-R-P-A-P-V-L-E-C-K-D-E-S-L-C-L-A-Y-Q-C-T-E-T-S-I-E-K-L-V-K-L-A-N-Q-N-P-S-Y-L-H-A-F-A-G-D-P-T-R-Q-P-E-Y-G-E-C-P-S-P-L-D-Y-Q-D-A-L-E-I-V-A-R-G-E-E-A-F-Y-S-L-P-A-N-I-R-V-N-F-S-N-P-M-E-F-L-S-W-L-E-D-P-A-N-Y-D-E-V-E-K-L-G-L-L-D-P-E-K-V-Q-I-R-K-S-K-L-Q-K-D-Q-K-E-E-V-S-S-E-E-K"} +{"text": "### FUNCTION Increases serum survival and confers group II surface exclusion ### SEQUENCE -M-Q-D-N-K-M-K-K-M-L-F-S-A-A-L-A-M-L-I-T-G-C-A-Q-Q-T-F-T-V-G-N-K-P-T-A-V-T-P-K-E-T-I-T-H-H-F-F-V-S-P-I-G-Q-R-K-L-L-M-Q-P-K-F-V-G-G-A-E-N-V-V-K-T-E-T-Q-Q-T-F-V-N-A-L-P-G-F-I-T-F-G-I-Y-T-P-R-E-T-R-V-Y-C-S-Q"} +{"text": "### FUNCTION Involved in host translation shutoff without degradating host RNA By suppressing host gene expression, facilitates the evasion from host type I interferon immune response ### SEQUENCE -M-N-N-S-K-D-N-P-F-R-G-A-I-A-R-K-A-R-I-Y-L-R-E-G-L-D-C-V-Y-F-L-N-K-A-G-Q-A-E-P-C-P-A-C-T-S-L-V-F-Q-G-K-T-C-E-E-H-I-H-N-N-N-L-L-S-W-Q-V-V-R-Q-L-E-R-Q-T-P-Q-R-Q-S-S-N"} +{"text": "### FUNCTION Stimulates sperm respiration and motility ### SEQUENCE -D-S-D-S-A-F-L-I-G"} +{"text": "### FUNCTION Stimulates sperm respiration and motility ### SEQUENCE -D-S-D-S-A-Q-N-L-I-G"} +{"text": "### FUNCTION Under resting conditions, inhibits trehalase in a dose-dependent manner ### SEQUENCE -A-I-P-T-P-H-V-Y-K-V-X-V-P-D-G-A-L-N-D"} +{"text": "### FUNCTION This protein is essential to promote the specific transfer of the plasmid in the presence of conjugative plasmids ### SEQUENCE -M-A-S-F-E-E-K-I-A-A-A-E-K-R-A-Q-E-A-A-K-Q-V-K-Q-L-K-A-K-R-D-M-V-E-A-R-K-L-Q-S-L-L-K-G-Q-R-S-D-D-T-R-R-K-I-L-V-G-A-L-V-L-D-M-M-E-R-D-E-S-T-R-Q-R-F-M-D-R-L-D-K-Y-L-T-R-A-D-D-R-A-L-F-Q-L-P-I-P-E-E-K"} +{"text": "### FUNCTION cCF10 is involved in the conjugative transfer of the hemolysin plasmid pCF10 ### SEQUENCE -L-V-T-L-V-F-V"} +{"text": "### FUNCTION This protein may be involved in virus assembly ### SEQUENCE -M-V-S-P-Q-T-R-K-E-E-E-L-L-E-K-Q-N-S-V-F-Y-L-L-T-L-G-R-K-P-Y-G-S-Y-L-H-I-K-I-E-L-D-E-D-E-K-L-E-K-E-I-Y-A-D-N-I-K-L-E-N-E-L-R-Q-L-K-R-L-Y-E-V-Y-Q-S-V-E-I-D-D-A-Q-K-A-I-Q-K-E-A-L-L-T-I-A-K-I-L-S-V-F-D-F"} +{"text": "### FUNCTION Essential for virus function ### SEQUENCE -M-K-A-E-E-T-I-V-E-Q-I-Q-D-I-I-Q-K-L-R-Y-Y-T-G-R-S-N-R-H-F-K-M-I-R-N-Y-Y-E-E-C-I-I-I-V-D-A-E-E-F-I-Q-E-N-N-T-L-S-I-T-V-Y-S-E-D-L-I-Y-Y-T-V-D-I-P-L-N-F-I-K-H-V-F-V-S-A-S-I-D-Q-L-N-D-Q-L-Q-L-K-Y-N-E-G-L-I-R-V-S-L-T-L-N-D-D-L-C-E-K-L-R-S-S-Y-C-G-D-I-T-F-F-N-E-A-E-G-Q"} +{"text": "### FUNCTION This protein may be involved in virus assembly Essential for virus function ### SEQUENCE -M-A-K-K-N-G-L-T-E-L-E-Q-L-K-K-E-N-E-E-L-R-K-K-L-E-E-L-E-A-L-I-N-N-D-S-D-D-D-E-E-L-Q-E-I-E-N-P-Y-T-V-T-N-R-A-I-D-E-L-V-S-P-K-D-T-M-F-Y-L-S-G-N-Q-I-S-L-I-L-S-A-F-E-F-A-R-L-P-T-Y-F-G-E-E-P-V-T-E-L-A-E-Y-A-H-K-L-K-H-Y-L-V-S-K-G-G-R-G-R-R-D-I-L-R-V-L-R-V-S-S-G-Q-T-R-E-N-V-N-K-S-I-L-K-Q-L-F-D-H-G-K-E-H-E-D-E-E-E"} +{"text": "### FUNCTION This protein may be involved in virus assembly ### SEQUENCE -M-S-A-L-G-D-V-I-Y-I-L-G-F-L-F-P-A-L-G-L-I-S-R-N-Y-L-V-N-L-M-A-F-I-I-G-T-V-A-F-L-V-F-V-Q-G-Y-T-D-I-A-F-S-S-S-T-F-Y-L-G-V-L-P-L-L-L-G-L-V-N-L-G-Y-F-F-N-W-L-R-E-E-R-I"} +{"text": "### FUNCTION This protein may be involved in virus assembly Essential for virus function ### SEQUENCE -M-T-D-A-I-S-L-A-L-Q-T-G-L-G-P-V-V-G-V-I-I-I-L-A-M-M-G-L-T-Y-K-I-A-G-K-I-P-A-I-I-T-G-I-A-S-A-F-V-L-M-F-M-D-F-L-P-L-F-W-G-I-A-I-I-F-G-L-I-A-G-M-V-V-T-R-D-G-D"} +{"text": "### FUNCTION Essential for virus function ### SEQUENCE -M-V-S-V-T-E-I-I-T-Y-G-R-E-A-I-E-R-I-I-C-K-Y-F-K-D-S-K-I-E-K-I-L-F-L-P-S-E-E-D-V-K-A-K-Y-I-I-G-R-V-G-F-I-R-I-S-N-T-W-S-G-I-V-V-V-D-G-V-Q-I-P-F-V-A-E-V-H-L-N-G-K-I-D-I-Y-L-Y-P-Q-K-D-F-Y-L-A-H-L-V-G-E-L-N-G"} +{"text": "### FUNCTION This protein may be involved in virus assembly ### SEQUENCE -M-K-K-L-F-T-V-V-G-S-I-F-S-G-L-G-I-W-L-K-S-I-D-Q-S-F-Y-L-T-K-V-L-Y-N-G-K-V-I-E-I-V-L-T-P-E-T-N-E-V-V-K-S-S-N-G-V-M-N-A-S-V-T-S-L-P-S-T-I-L-Y-Q-A-Q-S-V-P-S-I-N-G-G-T-L-S-V-I-N-T-T-V-Q-P-P-W-Y-A-N-L-W-P-E-V-L-T-I-G-I-V-M-L-G-I-A-I-F-S-W-I-K-L-K-F-R-R"} +{"text": "### FUNCTION This protein may be involved in virus assembly Essential for virus function ### SEQUENCE -M-G-T-K-L-V-V-Y-V-L-L-F-D-V-F-L-S-L-V-V-G-A-Y-S-G-I-A-P-P-S-I-P-P-V-P-T-Y-A-S-A-Q-L-T-A-S-L-I-T-W-T-V-G-W-P-P-I-T-L-W-P-Q-I-T-L-I-P-P-F-S-I-L-G-A-N-F-P-G-L-T-I-P-S-L-T-I-P-G-V-T-L-F-S-I-S-F-S-W-L-A-P-I-I-Y-I-A-N-W-I-I-W-V-F-Q-T-V-A-S-V-L-S-Y-L-L-N-I-F-T-G-S-V-G-L-L-S-S-V-P-V-L-G-P-F-L-T-A-F-V-L-I-V-N-F-V-L-V-W-E-L-I-K-L-I-R-G-S-E"} +{"text": "### FUNCTION Essential for virus function ### SEQUENCE -M-K-A-R-V-E-Y-I-K-L-P-R-C-Y-T-K-T-Y-R-K-I-E-A-K-K-N-N-D-G-T-I-E-L-T-L-E-E-T-M-Q-V-I-S-F-K-L-P-P-A-L-N-A-K-L-E-Q-I-A-I-K-E-K-K-S-K-S-E-I-I-R-I-A-L-A-R-Y-V-E-N-V"} +{"text": "### FUNCTION This protein may be involved in virus assembly ### SEQUENCE -M-R-W-G-R-R-D-D-R-D-T-G-K-I-L-R-N-R-S-R-N-R-F-N-I-Y-H-Y-V-S-T-V-K-K-V-K-E-T-E-R-E-L-L-R-L-T-Q-T-W-K-A-I-R-L-I-S-Y-N-S-V-G-I-S-I-N-R-L-T-S-R-L-I-H-K-L-H-E-L-L-N-G-L-I-S"} +{"text": "### FUNCTION This protein is non-essential for virus function ### SEQUENCE -M-D-Q-R-R-V-E-D-I-A-Q-I-G-A-Y-S-L-P-Y-D-I-V-N-I-V-Y-G-A-I-V-I-Y-R-A-S-Q-E-G-K-D-P-L-A-Y-A-S-N-K-Q-G-F-K-E-A-V-K-K-L-I-K-L-G-V-I-E-K-T-T-P-Y-S-L-K-K-E-Y-E-E-Q-V-E-K-F-D-E-I-I-N-Y-E-D-Y-E-R-A-R-Y-E-L-Y-K-L-S-E-K-A-D-N-L-F-T-S-S-L-V-L-Y-A-S-V-F-L-S-L-S-E-L-K-P-E-I-L-K-I-I-N-E-Y-I-D-Q-Q-T-K-V-D-Y-G-K-W-I-V-I-G-I-A-T-A-S-V-L-F-A-I-A-S-V-L-I-H-I-L-A-H-V-S-I-W"} +{"text": "### FUNCTION This protein is non-essential for virus function ### SEQUENCE -M-I-E-K-R-K-D-R-I-V-K-R-L-N-I-S-I-S-E-E-T-Y-E-T-L-Q-R-L-K-A-K-T-G-K-T-M-G-Q-L-I-E-E-A-V-K-L-L-E-A-E-E"} +{"text": "### FUNCTION Essential for virus function ### SEQUENCE -M-M-V-Q-V-P-I-F-D-L-L-K-L-L-D-V-L-G-I-D-S-I-S-F-R-V-L-N-E-Y-D-E-G-F-I-R-V-D-Y-L-E-E-A-L-Q-K-D-G-W-S-K-V-Y-N-E-S-E-D-P-N-Y-C-C-G-N-F-D-V-E-Y-A-N-N-G-Y-K-I-I-L-R-C-D-E-D-G-Y-V-F-Q-I-T-I-N-K-V-T"} +{"text": "### FUNCTION Essential for virus function ### SEQUENCE -M-A-Q-T-L-N-S-Y-K-M-A-E-I-M-Y-K-I-L-E-K-K-G-E-L-T-L-E-D-I-L-A-Q-F-E-I-S-V-P-S-A-Y-N-I-Q-R-A-L-K-A-I-C-E-R-H-P-D-E-C-E-V-Q-Y-K-N-R-K-T-T-F-K-W-I-K-Q-E-Q-K-E-E-Q-K-Q-E-Q-T-Q-D-N-I-A-K-I-F-D-A-Q-P-A-N-F-E-Q-T-D-Q-G-F-I-K-A-K-Q"} +{"text": "### FUNCTION Allows growth on lambda lysogens ### SEQUENCE -M-S-D-Y-L-K-V-L-Q-A-I-K-G-C-P-K-T-F-Q-S-N-Y-V-R-N-N-A-S-L-V-A-E-A-A-S-R-G-H-I-S-C-L-T-T-S-G-R-N-G-G-A-W-E-I-T-A-S-G-T-R-F-L-K-R-M-G-G-C-V"} +{"text": "### FUNCTION Acts as an inhibitor of bacterial RNA polymerase ### SEQUENCE -M-E-Q-R-E-I-K-Y-L-L-T-M-E-G-N-T-E-S-F-E-V-P-V-F-A-R-S-L-E-E-A-T-L-Q-A-E-Q-Y-E-D-A-G-F-V-V-T-R-I-R-P-E-V-K-A"} +{"text": "### FUNCTION Involved in erythromycin resistance ### SEQUENCE -M-L-I-S-G-T-A-F-L-R-L-R-T-N-R-K-A-F-P-T-P"} +{"text": "### FUNCTION Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier ### SEQUENCE -M-I-Y-E-T-L-V-L-S-K-T-E-L-E-Q-L-N-V-D-L-P-R-Y-S-Y-R-F-R-Y-S-R-S-I-G-D-T-V-V-E-F-P-G-T-L-S-D-P-C-I-P-V-V-D-V-L-L-G-A-C-W-A-W-P-Q-P-S-R-H-G-G-L-G-L-D-D-I-D-P-F-D-A-S-F-S-C-C-V-T-S-P-E-R-Y-C-L-S-R-S-V-L-S-G-V-D-A-F-V-V-R-G-S-C-K-L-C-G-L-G-F-L-D-N-F-N-P-F-E-I-R-A-L-L-G-Q-T-T-P-G-L-W-W-Q-P-V-K-P-V-Y-D-D-R-N-I-H-L-P-Y-D-S-E-L-N-A-R-I-Q-R-F-Q-Y-T-C-R-E-C-I-V-R-V-A-F-H-M-S-S"} +{"text": "### FUNCTION Involved in the depression of host DNA replication ### SEQUENCE -M-S-R-D-E-L-R-I-V-L-G-A-M-I-P-N-M-E-E-G-F-E-I-K-T-R-D-G-A-I-L-R-V-D-P-E-W-E-C-C-K-E-F-K-D-G-L-K-A-E-I-I-K-Q-L-K-S-K-P-A-V-V-F-G-Y-S"} +{"text": "### FUNCTION Induces the formation of large intracellular inclusion body, organized in amorphous and crystalline arrays Presumably the main cause of the stripe disease observed in host ### SEQUENCE -M-Q-R-S-A-D-V-S-I-G-P-I-T-G-L-N-Y-T-D-L-Y-D-S-L-P-S-S-V-S-D-N-I-T-L-L-D-L-K-E-P-E-R-V-T-E-A-T-K-K-L-I-L-K-G-C-V-E-T-A-Y-H-H-P-L-E-T-D-P-L-F-A-S-V-H-K-H-L-P-D-F-C-H-S-F-L-E-H-L-L-G-G-E-Q-D-E-N-S-L-I-D-I-G-E-F-F-K-L-L-Q-P-S-L-G-D-W-I-T-K-Y-Y-L-K-H-P-N-K-M-S-G-I-Q-I-K-T-L-L-N-Q-I-I-N-M-A-K-A-E-S-S-D-T-E-T-Y-E-K-V-W-K-K-M-P-S-Y-F-S-I-V-L-T-P-L-L-H-K-V-V"} +{"text": "### FUNCTION VP5 is not required for viral replication in vivo and its absence does not alter the virulence characteristics of the virus or the establishment of persistent IPNV infection ### SEQUENCE -M-A-K-A-L-S-N-K-Q-T-N-N-L-Y-S-I-Q-D-E-H-K-Q-G-N-R-N-L-L-E-I-H-Y-A-S-R-D-W-T-S-K-H-P-G-R-H-N-G-E-T-H-P-K-T-R-D-L-V-I-Q-P-R-G-L-R-I-R-K-W-H-S-C-L-F-P-W-G-T-R-L-T-D-R-C-T-L-Q-M-E-C-E-P-D-G-A-G-V-R-P-V-A-G-D-V-A-G-P-E-E-S-L-Q-L-R-E-A-D-L-K-E-I-R-H-P-K-L-H-T-T-G-R-S-L-C-S-E-R-D-A-Q-R-C-H-L-R-R-Q-S-V"} +{"text": "### FUNCTION Modulator protein affects the P1 c1 repression system ### SEQUENCE -M-K-K-R-Y-Y-T-V-K-H-G-T-L-R-A-L-Q-E-F-A-D-K-H-N-V-E-V-R-R-E-G-G-S-K-A-L-R-M-Y-R-P-D-G-K-W-R-T-V-V-D-F-K-T-N-S-V-P-Q-G-V-R-D-R-A-F-E-E-W-E-Q-I-I-I-D-N-A-L-L-L-N-A-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-S-L-S-L-G-S-K-I-L-I-L-L-I-R-G-Y-Q-L-G-I-S-P-L-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-G-I-E-A-L-R-R-F-G-M-I-K-G-S-W-L-T-V-K-R-I-L-K-C-H-P-L-H-E-G-G-D-D-P-V-P-P-R-K-N-D-D-N-R-E-N"} +{"text": "### FUNCTION VP5 is not required for viral replication in vivo and its absence does not alter the virulence characteristics of the virus or the establishment of persistent IPNV infection ### SEQUENCE -M-A-K-A-L-S-N-K-P-T-N-I-L-I-Y-M-N-H-E-H-I-Q-G-N-R-N-L-L-E-I-H-Y-A-S-R-E-W-A-S-K-H-S-G-R-H-N-R-E-A-Y-T-K-T-R-D-L-V-I-Q-L-R-G-I-R-I-R-K-W-A-S-C-L-L-P-R-S-S-W-I-Q-G-R-C-P-L-Q-V-E-S-E-P-D-G-T-R-I-R-P-V-A-R-D-V-T-G-P-K-E-G-I-Q-L-R-E-T-D-L-T-E-I-R-H-P-E-L-N-P-S-R-W-S-V-C-T-Q-W-D-P-E-R-C-H-L-R-R-K-S-V"} +{"text": "### FUNCTION Structural or assembly protein of tail fibers ### SEQUENCE -M-S-D-V-S-T-N-L-Y-K-S-Q-L-L-D-Y-Y-Y-Q-R-R-A-E-S-S-I-N-K-G-S-R-F-L-I-S-K-A-V-F-G-T-S-S-L-V-T-K-K-G-D-G-T-Y-E-I-G-E-L-P-K-A-F-E-L-A-E-L-T-S-Q-F-C-T-I-N-L-V-P-T-Y-S-G-G-I-I-T-V-R-M-D-L-D-Q-S-Q-L-Q-E-G-K-N-Y-P-F-N-T-L-V-V-L-D-N-E-N-K-P-I-A-I-I-C-V-Q-E-D-S-L-Y-V-G-K-T-Y-T-A-V-M-A-I-N-T-T-T-A"} +{"text": "### FUNCTION The terminase small subunit binds to the packaging initiation site and regulates the ATPase activity of the terminase large subunit The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition , and a large terminase subunit possessing endonucleolytic and ATPase activities Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer at the long non-permuted direct terminal repeats Once the capsid is packaged with the DNA, the terminase complex is substituted by neck proteins ### SEQUENCE -M-A-N-D-V-L-V-P-D-L-M-S-P-E-G-M-D-V-I-E-A-Y-L-Q-C-G-S-D-V-P-S-A-A-R-S-L-G-M-S-E-I-A-F-R-D-I-M-N-R-S-E-V-K-N-Y-L-N-D-I-F-M-E-S-G-F-R-N-R-D-R-L-F-G-V-L-D-E-V-I-K-R-K-L-E-E-L-E-E-T-G-M-G-S-D-Q-D-I-M-D-I-L-W-K-A-H-K-M-K-M-E-E-M-K-M-M-V-E-L-E-K-V-K-A-A-A-R-T-P-A-N-Q-T-N-I-Q-N-N-I-I-A-G-A-G-D-Q-N-Y-M-D-L-I-T-S-L-A-T-G-G-K-K"} +{"text": "### FUNCTION May regulate expression of the erythromycin resistance protein ### SEQUENCE -M-T-A-S-M-R-L-K"} +{"text": "### FUNCTION Plays a role for multiplication of the virus in different cell types ### SEQUENCE -M-G-I-T-H-E-L-D-I-F-L-V-S-E-D-I-A-M-K-H-V-E-L-H-K-G-N-S-Y-G-C-V-L-N-I-K-S-S-C-R-K-Q-M-K-I-I-F-V-L-K-P-D-W-T-E-I-D-S-I-K-P-I-Q-M-E-A-D-G-I-Y-I-D-V-T-I-I-K-Q-S-F-Y-E-V-I-Y-C-S-N-F-T-I-Y-G-D-S-V-I-N-I-F-S-D-I-D-R-C-T-K-E-K-Y-P-I-I-N-I-N-I-D-K-K-K-Y-E-I-I-E-S-G-Y-T-Y-I-Y-I-Q-S-P-I-D-K-E-D-K-L-T-Y-M-R-D-D-Y-V-D-E-Y-N-S-S-D-D-D-C-I-D-Y-Y-D-C-D-Y-D-D-D-D-N-N-D-A-E-D-E-D-E-E"} +{"text": "### FUNCTION Seems to be required for the LH-II stabilization ### SEQUENCE -M-T-D-N-I-M-K-D-H-R-H-I-F-L-P-Q-P-V-K-A-D-E-K-P-G-A-F-S-E-R-F-G-W-K-L-L-L-D-T-P-R-K-K-N-V-Y-E-G-T-K-F-M-S-Q-D-F-W-P-T-P-L-V-K-T-T-A-P-K-V-K-L-I-P-A-D-A-P-P-Q-S-A-K-F-W-K-A-P-L-L-K-D-T-P-R-Q-S-N-V-I-P-G-D-F-L-P-F-S-N-T-F-G-L-A-T-I-Q-R-R"} +{"text": "### FUNCTION Seems to be required for the LH-II stabilization ### SEQUENCE -M-T-T-V-I-T-R-L-Y-A-D-E-K-T-A-C-D-I-A-R-Q-L-K-S-E-G-I-P-K-R-A-L-K-V-V-V-A-D-G-K-K-G-A-A-L-A-E-A-L-K-S-A-G-V-H-P-S-A-A-A-G-Y-A-E-R-V-A-G-G-L-P-L-V-A-K-V-N-Y-K-P-L-G-A-A-K-L-V-R-A-I-T-A-R-A-R-W-S-R-S-R-T-Q-P-K-S-S-P-V-R-T-H-L-K"} +{"text": "### FUNCTION Putative sugar-binding regulatory protein for the alpha-amylase gene ### SEQUENCE -G-D-V-S-V-V-G-F-D-D-S-P-L-I-A-F-T-S-P-P-L-S-T-V-R-Q-P-V-Q-A-M-A-T-A-A-V-G-A-L-L-E-E-I-E-G-N-P-V-Q-R-T-E-F-V-F-Q-P-E-L-V-V-R-G-S-T-A-Q-P-P-G-R-V-S-Q-V-L-S"} +{"text": "### FUNCTION Involved in the resistance of the fungal toxin fusaric acid ### SEQUENCE -M-Q-I-D-P-S-H-Y-Q-I-A-V-E-Q-A-Q-A-V-A-A-A-A-R-S-C-R-C-R-R-R-G-R-R-A-D-L-D-A-L-V-V-S-K-E-N-R-E-N-A-A-H-S-A-S-S-A-D-A-Q-Y-Q-Q-A-I-A-A-L-D-A-R-S-S-T-L-E-R-S-R-V-V-A-P-V-D-G-Y-I-T-N-L-Q-T-F-K-G-N-Y-A-V-A-G-Q-A-K-L-A-I-V-D-S-H-S-F-W-V-Y-G-Y-F-E-E-T-K-L-P-R-V-K-I-G-A-P-A-E-M-R-L-M-S-G-G-V-M-K-G-H-V-E-S-I-S-R-G-I-Y-D-R-D-N-P-Q-S-R-D-L-V-R-T"} +{"text": "### FUNCTION Expressed but non-essential protein, involved in the virulence of Salmonellas ### SEQUENCE -M-L-R-A-T-K-V-C-I-Y-P-T-P-E-Q-A-E-H-L-N-A-Q-F-G-A-V-R-F-V-Y-S-K-S-L-H-I-K-K-H-A-Y-Q-R-H-G-V-S-L-T-P-R-K-D-I-K-P-L-L-A-V-A-K-K-F-R-K-F-R-K-F-R-K-Y-A-W-L-K-E-Y-D-S-I-A-L-Q-Q-A-V-I-N-L-D-V-A-F-S-N-C-F-N-P-K-L-K-A-R-F-P-M-F-K-R-K-H-G-K-L-L-G"} +{"text": "### FUNCTION Late protein which is part of a large complex required for early virion morphogenesis This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions ### SEQUENCE -M-E-L-D-I-K-K-L-T-D-L-L-Q-N-N-K-T-V-C-P-C-D-I-K-K-I-Y-D-E-R-F-I-V-L-E-K-G-R-C-M-I-R-N-I-H-V-Y-S-S-A-A-R-F-D-N-K-T-M-F-G-V-I-K-Y-L-Y-K-H-N-E-A-I-I-D-M-L-F-P-S-K-T-V-Y-N-S-I-R-E-I-A-P-D-Y-T-V-S-I-S-T-D-D-T-E-P-S-N-P-V-T-V-L-L-N-I-F-N-S-F-R-F-G-K-K-D-A-P-V-S-Y-Y-Y-L-P-F-G-K-D-V-H-D-V-I-S"} +{"text": "### FUNCTION Cell-to-cell movement ### SEQUENCE -M-E-N-T-E-N-V-R-S-G-R-N-Q-R-E-Y-S-K-E-R-Q-Q-E-G-G-Y-K-E-V-S-K-A-A-V-R-K-E-G-D-V-K-Q-D-M-G-P-S-V-S-M-T-V-V-G-E-K-V-E-F-T-Q-H-F-H-F"} +{"text": "### FUNCTION Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier ### SEQUENCE -M-A-M-V-R-A-D-A-D-R-E-S-L-G-E-G-L-L-Q-E-R-S-Q-W-L-W-S-L-P-T-A-Q-P-G-A-E-D-A-D-D-Q-L-V-L-G-E-E-E-L-Q-D-L-E-E-E-A-V-A-R-H-S-F-S-Q-R-I-H-S-R-A-T-P-L-E-V-S-P-S-G-R-L-Y-Q-S-I-R-H-S-R-M-E-Y-S-R-P-T-M-N-I-R-S-Q-I-V-S-Y-S-S-S-A-R-P-L-P-Q-Q-P-A-P-S-L-T-S-W-T-P-I-A-K-H-L-H-S-H-Q-Q-S-I-S-S-Q-S-P-K-L-V-R-G-A-S-Q-R-R"} +{"text": "### FUNCTION Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier ### SEQUENCE -M-A-Q-G-E-Q-G-A-L-A-Q-F-G-E-W-L-W-S-N-P-I-E-P-D-Q-N-D-E-L-V-D-A-Q-E-E-E-G-Q-I-L-Y-L-D-Q-Q-A-G-L-R-Y-S-Y-S-Q-S-T-T-L-R-P-T-P-Q-G-Q-S-S-S-V-P-T-F-R-N-A-Q-R-F-Q-V-E-Y-S-S-P-T-T-F-T-R-S-Q-T-S-R-L-S-L-S-H-T-R-P-P-L-Q-S-A-Q-C-L-L-N-S-T-L-G-A-H-N-Q-P-W-V-A-T-L-T-H-S-P-S-Q-N-Q-Q-P-K-P-S-P-P-N-R-L-T-G-R-N-S-G-R-V-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-K-L-S-T-I-V-V-F-C-L-T-F-F-V-S-I-Y-Q-N-Y-I-S-F-F-M-P-S-N-C-R-F-Y-P-T-C-S-T-Y-M-I-L-S-L-R-K-F-G-V-I-K-G-I-I-L-T-I-L-R-L-F-K-C-H-P-L-H-Q-G-G-E-D-L-V-P-L-K-I-K-D-K-S-E-Y"} +{"text": "### FUNCTION Suppression of Atumefaciens oncogenicity ### SEQUENCE -M-L-M-L-L-R-R-R-C-R-A-W-L-E-I-R-R-L-D-K-E-L-A-Q-S-S-G-L-P-L-E-L-P-Q-I-V-P-N-A-W-N-E-V-V-W-R-L-P-V-P-N-H-P-D-A-F-M-T-A-S-N-A-A-Q-S-D-F-I-V-Y-V-N-G-L-A-F-Y-R-A-W-L-A-L-G-V-E-D-S-Q-A-C-P-L-K-Q-D-M-P-K-D-R-K-Y-P-S-S-A-A-H-F-A-V-G-I-D-S-P-V-P-L-A-D-V-S-P-T-M-I-L-G-H-F-A-V-C-F-T-D-G-M-T-R-S-M-W-L-L-A-H-E-V-A-V-F-P-V-L-S-R-D-E-A-S-A-V-M-L-A-E-H-V-G-V-A-A-P-I-Q-V-S-K-L-R-E-Q-C-R-K-I"} +{"text": "### FUNCTION Not required for the biogenesis of c-type cytochromes ### SEQUENCE -M-A-P-R-E-P-G-F-A-G-A-L-P-I-D-G-Y-G-P-G-F-F-R-I-A-G-A-V-H-R-G-G-L-L-I-H-A-E-A-A-M-P-W-T-G-F-D-D-L-A-A-L-R-A-L-A-G-Q-V-D-L-L-L-C-G-M-G-A-D-I-A-H-L-P-K-G-L-Q-V-E-L-E-A-L-G-V-M-A-E-P-M-S-T-A-S-A-A-R-H-Y-N-V-L-L-S-E-G-R-R-V-G-A-A-L-L-P-M-P-G-A-V-P-T-A"} +{"text": "### FUNCTION Involved in resistance to IFN ### SEQUENCE -M-I-Q-S-P-T-S-F-L-I-V-L-I-L-L-W-C-K-L-V-L-S-C-F-I-E-C-L-V-A-L-Q-Q-L-I-H-V-L-L-Q-I-I-N-S-N-L-Q-S-R-L-L-L-W-H-S-L-D"} +{"text": "### FUNCTION Involved in resistance to IFN ### SEQUENCE -M-I-Q-S-P-T-S-F-L-I-V-L-V-L-L-W-C-K-L-V-I-S-C-F-R-E-C-F-V-A-L-H-Q-L-V-Q-V-L-L-Q-I-I-N-S-N-L-Q-S-R-L-L-L-W-H-S-L-D"} +{"text": "### FUNCTION Involved in resistance to IFN ### SEQUENCE -M-I-Q-S-P-T-S-F-L-I-V-L-I-L-L-W-C-K-L-V-I-S-C-F-R-E-C-I-V-A-L-Q-Q-L-I-Q-V-L-L-Q-I-I-N-S-N-L-Q-S-R-L-L-L-W-H-S-L-D"} +{"text": "### FUNCTION No function has yet been ascribed to K protein ### SEQUENCE -M-K-H-V-N-T-L-L-M-Q-E-L-R-L-L-I-C-E-L-K-R-L-R-L-S-A-V-S-D-P-D-F-S-Q-E-K-I-H-A-E-L-D-S-L-L-C-K-L-S-R-H-F-D"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Involved in the biosynthesis of the FeCO cofactor ### SEQUENCE -M-C-L-A-I-P-A-R-L-V-E-L-Q-A-D-Q-Q-G-V-V-D-L-S-G-V-R-K-T-I-S-L-A-L-M-A-D-A-V-V-G-D-Y-V-I-V-H-V-G-Y-A-I-G-K-I-D-P-E-E-A-E-R-T-L-R-L-F-A-E-L-E-R-V-Q-P-P-A-S-E-P-M-H-G-M-N-I-H-Q-E-P-A"} +{"text": "### FUNCTION Involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification ### SEQUENCE -T-S-P-N-I-N-G-F-W-V-M-L-E-N-D-E-Q-I-E-F-P-I-K-P-L-I-D-H-A-R-P-T-F-R-Q-I-M-S-R-F-S-D-L-A-E-A-Y-I-E-K-R-N-F-E-R-A-Y-M-P-R-Y-G-L-Q-R-N-L-T-D-M-S-L-R-R-Y-A-F-D-F-Y-E-M-T-S-K-A-P-A-R-A"} +{"text": "### FUNCTION Homolog of shope fibroma virus T4A ORF ### SEQUENCE -M-L-S-Y-I-I-N-P-L-L-S-I-V-Y-F-I-L-G-N-V-S-K-L-L-T-Y-I-L-M-K-I-M-I-F-L-L-R-A-V-N-P-Y-S-L-I-S-N-R-G-W-L-S-L-D-S-I-N-P-F-K-K-E-K-R-R-E-S-F-L-S-S-L-N-P-F-R-K-E-E-T-K-K-K-E-G-F-F-S-G-W-F-G"} +{"text": "### FUNCTION Imparts immunity to lactococcin-B to naturally sensitive host strains ### SEQUENCE -M-K-K-K-V-D-T-E-K-Q-I-T-S-W-A-S-D-L-A-S-K-N-E-T-K-V-Q-E-K-L-I-L-S-S-Y-I-Q-D-I-E-N-H-V-Y-F-P-K-A-M-I-S-L-E-K-K-L-R-D-Q-N-N-I-C-A-L-S-K-E-V-N-Q-F-Y-F-K-V-V-E-V-N-Q-R-K-S-W-M-V-G-L-I-V"} +{"text": "### FUNCTION Has some function in curvacin a biosynthesis, transport or resistance ### SEQUENCE -M-I-I-A-E-N-F-V-Q-R-L-L-A-L-Q-L-I-I-I-L-R-F-L-I-V-W-L-N-Y-C-Q-L-L-K-K-L-R-R-G-L-D-L-V-R-M-I-F-I-L-S-I"} +{"text": "### FUNCTION Not yet known ### SEQUENCE -M-S-N-G-A-A-D-R-A-R-L-R-H-L-D-H-C-R-Q-P-H-C-F-A-R-D-I-C-V-F-T-Y-F-E-L-P-E-E-H-P-Q-G-P-A-H-G-V-R-I-T-V-E-K-G-I-D-T-H-L-I-K-F-F-T-K-R-P-L-L-V-E-K-D-Q-G-N-T-I-L-T-L-Y-C-I-C-P-V-P-G-L-H-E-D-F-C-C-H-L-C-A-E-F-N-H-L"} +{"text": "### FUNCTION It is proposed that R and S are tail completion proteins that are essential for stable head joining ### SEQUENCE -M-L-K-P-D-S-L-R-R-A-L-T-D-A-V-T-V-L-K-T-N-P-D-M-L-R-I-F-V-D-N-G-S-I-A-S-T-L-A-A-S-L-S-F-E-K-R-Y-T-L-N-V-I-V-T-D-F-T-G-D-F-D-L-L-I-V-P-V-L-A-W-L-R-E-N-Q-P-D-I-M-T-T-D-E-G-Q-K-K-G-F-T-F-Y-A-D-I-N-N-D-S-S-F-D-I-S-I-S-L-M-L-T-E-R-T-L-V-S-E-V-D-G-A-L-H-V-K-N-I-S-E-P-P-P-P-E-P-V-T-R-P-M-E-L-Y-I-N-G-E-L-V-S-K-W-D-E"} +{"text": "### FUNCTION Antibacterial peptide Affects Gram-negative bacteria ### SEQUENCE -D-V-E-L-K-G-K-G-G-E-N-E-G-F-V-G-L-K-A-Q-R-N-L-Y-E-D-D-R-T-S-L-S-G-T-V-K-G-Q-S-Q-W-K-D-P-Y-P-A-Q-H-A-G-M-A-R-L-D-G-T-R-T-L-I-E-N-D-R-T-K-V-T-G-S-G-F-A-Q-R-E-V-A-T-G-M-R-P-H-D-S-F-G-V-G-V-E-A-T-H-N-I-Y-K-G-K-N-G-E-V-D-V-F-G-G-V-Q-R-Q-W-N-T-P-D-R-H-Q-A-R-G-G-I-R-W-R-F"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-P-G-L-D-S-P-A-A-V-R-R-A-A-M-D-L-L-A-R"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-R-Q-P-I-E-K-S-L-R-Q-R-A-L-E-Y-L-S-K-R-E-Y-S-A-V-E-L-A-Q-K-L"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-L-T-R-T-R-V-R-Q-G-H-G-P-L-R-L-R-Q-D-L-Q-R-A-G-V-E-A-T-A-A-L-E-I-D-W-L-Q-Q-A-Q-A-V-C-Q-K-R-F-G-D-T-P-P-T-D-A-R-D-Y-A-R-R-A-R-F-L-A-G-R-G-F-T-G-E-T-I-R-R-V-L-G-A-G-R-E-R-D-F-S-A-D"} +{"text": "### FUNCTION Could impart immunity to carnobacteriocin-BM1 to naturally sensitive host strains ### SEQUENCE -M-I-K-D-E-K-I-N-K-I-Y-A-L-V-K-S-A-L-D-N-T-D-V-K-N-D-K-K-L-S-L-L-L-M-R-I-Q-E-T-S-I-N-G-E-L-F-Y-D-Y-K-K-E-L-Q-P-A-I-S-M-Y-S-I-Q-H-N-F-R-V-P-D-D-L-V-K-L-L-A-L-V-Q-T-P-K-A-W-S-G-F"} +{"text": "### FUNCTION Identified as a multicopy suppressor of the slow growth phenotype of an rsgA deletion mutant ### SEQUENCE -M-N-G-A-T-S-L-Y-D-E-V-I-I-I-N-K-I-P-P-K-K-I-D-T-K-G-V-A-T-E-E-V-A-T-K-K-V-L-L-N-K-L-L-T-T-Q-L-L-N-E-P-E"} +{"text": "### FUNCTION May be involved in metabolic processes ### SEQUENCE -M-Y-K-V-S-A-C-G-V-R-I-M-S-G-I-S-E-I-W-I-G-E-L-R-D-Y-K-Y-A-L-R-L-D-R-E-E-Y-P-A-V-L-V-Y-E-Y-D-S-S-S-T-R-N-Y-L-F-T-I-K-Y-S-D-Q-R-P-N-W-Q-L-I-T-R-D-A-A-L-T-A-Y-D-L-L-N-R-G-G-E-F-T-T-L-S-F-P-G-A-T-I-H-R-S-V-S-E-L-S-R-L-H"} +{"text": "### FUNCTION May be involved in phosphatase regulation and/or generation of precursor metabolites and energy ### SEQUENCE -M-G-L-S-R-W-H-D-K-N-S-R-P-A-E-E-K-S-E-E-M-Q-Q-D-A-H-Y-Y-A-L-A-A-S-D-S-L-N-A-S-V-S-N-E-Y-G-N-Q-V-M-N-S-F-W-K-V-G-I-D-S-P-Y-V-D-D-E-A-I-R-N-R-D-V-E-N-N-L-P-S-L-K-Q-S-V-Y-N-A-N-E-P-N-A-T-S-S-A-F-S-T-A-S-Y-A-H-E-T-F-D-F-R-N-L-K-L-R"} +{"text": "### FUNCTION Involved in the maturation of hydrogenases Involved in the biosynthesis of the FeCO cofactor ### SEQUENCE -M-C-L-G-I-P-G-Q-I-V-A-I-T-D-A-G-R-M-M-A-L-A-D-V-S-G-V-K-R-A-V-N-V-A-C-V-A-E-G-P-L-E-D-L-L-G-H-W-A-L-I-H-V-G-F-A-M-S-L-I-D-E-A-E-A-A-R-T-L-E-A-L-R-D-L-G-E-A-Q-E-T-L-A-Q-M-A-E-G-A-A-A-L-E-G-R-G"} +{"text": "### FUNCTION Plays a role in late gene expression ### SEQUENCE -M-T-M-E-N-N-A-E-F-N-R-R-L-E-Y-V-G-T-I-A-T-M-M-K-R-T-L-N-V-L-R-Q-Q-G-Y-C-T-Q-Q-D-A-D-S-L-C-V-S-D-D-T-A-A-W-L-C-G-R-L-P-T-C-N-F-V-S-F-R-V-H-I-D-Q-F-E-H-P-N-P-A-L-E-Y-F-K-F-E-E-S-L-A-Q-R-Q-H-V-G-P-R-Y-T-Y-M-N-Y-T-L-F-K-N-V-V-A-L-K-L-V-V-Y-T-R-T-L-Q-A-N-M-Y-A-D-G-L-P-Y-F-V-Q-N-F-S-E-T-S-Y-K-H-V-R-V-Y-V-R-K-L-G-A-I-Q-V-A-T-L-S-V-Y-E-Q-I-I-E-D-T-I-N-E-L-V-V-N-H-V-D"} +{"text": "### FUNCTION Plays a role in the production of occlusion bodies as well as expression of the polyhedrin gene ### SEQUENCE -M-N-T-R-Y-A-T-C-Y-V-C-D-E-L-V-Y-L-F-K-K-T-F-S-N-M-S-P-S-A-A-A-F-Y-Q-R-R-M-A-I-V-K-N-G-I-V-L-C-P-R-C-S-S-E-L-K-I-G-N-G-V-S-I-P-I-Y-P-H-R-A-Q-Q-H-A-R-R-S-R"} +{"text": "### FUNCTION Plays a role in the expression of ORF41, which itself is required for late gene expression ### SEQUENCE -M-L-P-Y-E-M-V-I-A-V-L-V-Y-L-S-P-A-Q-I-L-N-L-N-L-P-F-A-Y-Q-K-S-V-L-F-A-S-N-S-A-K-V-N-E-R-I-R-R-R-A-R-D-D-N-D-D-D-P-Y-F-Y-Y-K-Q-F-I-K-I-N-F-L-T-K-K-I-I-N-V-Y-N-K-T-E-K-C-I-R-A-T-F-D-G-R-Y-V-V-T-R-D-V-L-M-C-F-V-N-K-S-Y-M-K-Q-L-L-R-E-V-D-T-R-I-T-L-Q-Q-L-V-K-M-Y-S-P-E-F-G-F-Y-V-N-S-K-I-M-F-V-L-T-E-S-V-L-A-S-I-C-L-K-H-S-F-G-K-C-E-W-L-D-K-N-I-K-T-V-C-L-Q-L-R-K-I-C-I-N-N-K-Q-H-S-T-C-L-S-Y"} +{"text": "### FUNCTION Plays an essential role in the process of oral infection May participate in the crossing of occlusion-derived virions through the host peritrophic membrane during oral infection ### SEQUENCE -M-K-Y-F-L-S-A-T-F-L-I-I-V-F-M-Y-L-M-Y-F-C-I-S-I-V-V-N-N-A-R-V-Q-Q-D-L-F-Y-H-Y-N-Y-V-P-D-T-L-L-N-T-V-R-V-H-K-L-K"} +{"text": "### FUNCTION Stimulates the expression of 39k gene most probably by increasing IE1 expression ### SEQUENCE -M-M-S-S-S-Q-I-I-V-C-N-K-I-N-I-F-V-C-K-Y-N-L-L-Q-I-N-F-T-L-N-Q-S-V-F-V-F-V-V-R-S-S-N-L-V-F-Q-P-L-G-M-V-K-M-R-R-S-N-C"} +{"text": "### FUNCTION Acts as a transactivator of AC102 and HE65 genes Therefore, participates in the global recruitment of G-actin to the host nucleus ### SEQUENCE -M-N-F-F-A-M-Q-K-S-S-L-L-P-D-T-P-Y-T-V-Q-S-L-Q-I-V-D-Y-F-I-R-I-V-Y-T-V-R-Y-A-P-N-I-L-L-H-Y-Q-L-F-C-I-T-K-K-F-I-F-A-W-Q-V-P-P-P-L-L-S-Y-Q-S-C-S-T-D-K-Q-Y-K-Y-S-C-R-S-T-R-K-H-S-S-S-L-T-A"} +{"text": "### FUNCTION Disorganizes the host nucleoid and inhibits replication, but without host DNA cleavage or degradation Only the architecture of the nucleoid is affected May act on the host chromosomal sequences that determine the structure of the nucleoid Binds to dsDNA but not to ssDNA ### SEQUENCE -M-K-Y-M-T-V-T-D-L-N-N-A-G-A-T-V-I-G-T-I-K-G-G-E-W-F-L-G-T-P-H-K-D-I-L-S-K-P-G-F-Y-F-L-V-S-K-L-G-G-P-F-S-S-P-C-V-S-A-R-F-Y-V-G-N-Q-R-S-K-Q-G-F-S-A-V-L-S-H-I-R-Q-R-R-S-Q-L-A-R-T-I-A-N-N-N-V-P-Y-T-V-F-Y-L-P-A-S-K-M-K-P-L-T-T-G-F-G-K-G-Q-L-A-L-A-F-T-R-N-H-H-S-E-Y-Q-T-L-E-E-M-N-R-M-L-A-D-N-F-K-F-V-L-Q-A-Y"} +{"text": "### FUNCTION Disorganizes the host nucleoid and inhibits replication, but without host DNA cleavage or degradation Only the architecture of the nucleoid is affected May act on the host chromosomal sequences that determine the structure of the nucleoid Binds to dsDNA but not to ssDNA ### SEQUENCE -M-K-Y-M-T-V-T-D-L-N-N-A-G-A-T-V-I-G-T-I-K-G-G-E-W-F-L-G-T-P-H-K-D-I-L-S-K-P-G-F-Y-F-L-V-S-K-L-D-G-R-P-F-S-N-P-C-V-S-A-R-F-Y-V-G-N-Q-R-S-K-Q-G-F-S-A-V-L-S-H-I-R-Q-R-R-S-Q-L-A-R-T-I-A-N-N-N-M-V-Y-T-V-F-Y-L-P-A-S-K-M-K-P-L-T-T-G-F-G-K-G-Q-L-A-L-A-F-T-R-N-H-H-S-E-Y-Q-T-L-E-E-M-N-R-M-L-A-D-N-F-K-F-V-L-Q-A-Y"} +{"text": "### FUNCTION Disorganizes the host nucleoid and inhibits replication, but without host DNA cleavage or degradation Only the architecture of the nucleoid is affected May act on the host chromosomal sequences that determine the structure of the nucleoid Binds to dsDNA but not to ssDNA ### SEQUENCE -M-K-Y-M-T-V-T-D-L-N-N-A-G-A-T-V-I-G-T-I-K-G-G-E-W-F-L-G-T-P-H-K-D-I-L-S-K-P-G-F-Y-F-L-V-S-E-F-D-G-S-C-V-S-A-R-F-Y-V-G-N-Q-R-S-K-Q-G-F-S-A-V-L-S-H-I-R-Q-R-R-S-Q-L-A-R-T-I-A-N-N-N-M-A-Y-T-V-F-Y-L-P-A-S-K-M-K-P-L-T-T-G-F-G-K-G-Q-L-A-L-A-F-T-R-N-H-H-S-E-Y-Q-T-L-E-E-M-N-R-M-L-A-D-N-F-K-F-V-L-Q-A-Y"} +{"text": "### FUNCTION May be a DNA-binding protein involved in virion nucleoprotein condensation ### SEQUENCE -M-A-R-S-K-K-G-K-N-L-I-Y-V-L-L-G-L-V-G-L-L-A-F-F-V-L-F-V-P-T-L-T-I-S-A-S-T-P-V-W-L-E-N-T-I-T-Y-A-T-S-F-R-D-A-F-N-V-S-G-M-V-Y-M-V-I-L-L-G-V-L-I-A-Y-L-L-L-K-Y-S-K-T-R-Q-N-K-D-A-L-K-V-V-L-A-V-V-I-A-F-A-V-Y-L-L-F-T-P-A-L-A-A-A-F-S-D-Q-V-W-L-V-D-F-S-K-L-A-T-D-I-T-S-F-I-D-T-N-N-G-F-L-T-I-I-A-G-L-G-A-L-T-F-F-I-V-K-K-S-K"} +{"text": "### FUNCTION Involved in mitomycin resistance May operate with McrA or may be a type of transcriptional activator protein ### SEQUENCE -M-T-S-S-D-G-S-D-L-T-T-L-V-N-V-G-R-S-V-A-R-Y-F-E-R-I-G-I-T-E-I-A-Q-L-R-D-R-D-P-V-E-L-Y-E-R-M-S-A-A-F-G-Q-R-L-D-P-C-L-L-D-T-V-M-S-A-V-D-Q-A-E-G-L-P-A-R-P-W-W-H-Y-T-P-E-R-K-R-L-L-A-G-E-G-H-D-R-A-G-G-T-A-G-E-G-T-A"} +{"text": "### FUNCTION Displays ATPase and GTPase activities ### SEQUENCE -M-R-F-L-V-L-T-G-L-S-G-A-G-K-T-T-A-R-G-F-L-E-D-L-G-Y-F-M-V-D-N-L-P-P-R-L-W-P-P-L-L-Q-E-A-A-A-R-G-L-A-R-V-G-V-V-V-D-A-R-A-L-A-F-F-Q-D-L-E-E-V-L-E-A-L-R-P-T-V-V-Y-L-E-A-R-P-E-V-L-L-R-R-Y-N-L-T-R-R-V-H-P-L-G-A-G-N-L-M-R-E-I"} +{"text": "### FUNCTION May control expression of its associated restriction-modification system HgiCI ### SEQUENCE -M-T-F-G-T-F-K-L-K-P-K-P-E-H-L-E-G-V-L-N-V-L-A-Q-K-I-F-A-S-P-H-I-I-A-K-E-S-G-L-S-L-T-A-V-K-C-A-L-A-Q-L-E-Q-E-D-Q-L-I-I-K-H-Q-L-T-S-P-K-L-Q-V-A-L-K-D-K-S-S-D-V-N-I-S-A-T-S-D-P-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-E-T-H-S-L-G-T-K-I-L-I-K-I-I-R-L-Y-Q-I-M-I-S-P-F-I-G-A-R-C-R-F-V-P-T-C-S-C-Y-G-I-E-A-L-K-T-H-G-L-L-K-G-G-W-L-T-L-K-R-V-L-K-C-H-P-L-N-A-G-G-F-D-P-V-P-P-K-T-N-N-N-D-E-K-K"} +{"text": "### FUNCTION Binds one mole of molybdenum per mole of protein and contains a pterin ### SEQUENCE -M-K-I-S-A-R-N-Q-L-K-G-K-V-V-S-I-E-N-G-S-V-N-A-I-V-H-I-D-I-G-G-G-N-V-L-S-S-T-V-S-L-A-A-V-K-E-L-N-L-E-V-G-K-E-A-Y-A-I-I-K-A-T-S-V-M-V-G-V-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Y-K-Q-I-V-H-A-I-G-K-A-I-Q-T-L-L-L-G-L-I-K-S-Y-R-Y-L-I-S-P-V-L-M-S-S-C-R-F-Y-P-S-C-S-C-Y-A-E-T-A-L-K-R-F-G-V-I-K-G-S-G-L-T-V-W-R-L-L-R-C-H-P-F-H-P-G-G-V-D-F-V-P-E-K-S-N-E-M-V"} +{"text": "### FUNCTION Could be required for the biogenesis of a putative fimbria ### SEQUENCE -M-I-M-G-Q-L-M-N-M-R-E-L-F-N-K-K-K-L-H-A-L-V-F-S-M-W-C-V-N-L-H-A-S-S-L-S-D-G-I-A-I-E-P-F-E-I-N-A-K-S-N-R-F-V-E-F-K-V-Y-N-N-T-D-E-D-Y-I-V-T-Q-K-V-V-S-E-E-N-S-I-K-K-A-K-I-P-F-V-V-N-P-P-I-R-L-L-R-K-R-S-D-A-A-M-G-I-I-Y-L-N-E-G-E-V-F-D-K-K-R-K-Y-Y-L-S-V-S-F-I-P-K-K-K-D-S-D-D-L-G-F-N-I-I-F-T-Q-Q-I-A-V-K-L-S-A-L-N"} +{"text": "### FUNCTION Might be involved in Fe ### SEQUENCE -M-T-G-F-T-I-E-G-S-S-L-K-L-L-K-P-Q-E-Q-G-V-V-S-R-I-D-S-S-R-G-D-F-V-A-Q-K-L-R-S-M-N-I-T-L-G-T-R-V-T-V-E-Q-R-S-P-R-F-L-L-R-V-G-A-D-Q-V-A-L-S-D-P-L-Q-D-A-I-Y-V-R-L-S-R"} +{"text": "### FUNCTION This protein is involved in control of the biosynthesis of tryptophan ### SEQUENCE -M-I-F-V-A-T-S-L-S-C-R-W-W-W-P-V-M"} +{"text": "### FUNCTION Accessory protein needed to activate excisive recombination Appears to serve the additional function of repressing the production of the lysogenic repressor ### SEQUENCE -M-S-K-Q-N-A-I-C-I-N-I-H-M-E-Q-P-Y-M-T-R-E-E-F-A-K-K-L-D-V-S-T-R-T-I-D-R-L-R-Q-Q-G-V-L-K-C-I-K-M-K-N-D-E-G-E-E-T-E-R-G-L-V-L-V-D-L-V-A-I-A-V-R-N-A-K-N-A-F-Q-I"} +{"text": "### FUNCTION Putative tail protein ### SEQUENCE -M-K-I-K-L-P-F-W-M-D-K-G-E-L-S-K-I-A-V-L-F-G-K-W-W-D-Y-V-L-S-A-V-K-F-P-F-N-I-L-D-E-E-H-C-S-E-R-I-L-N-L-I-A-Y-Q-R-D-V-E-R-F-E-G-E-P-L-E-L-F-R-K-R-V-K-Y-A-F-L-N-A-K-D-A-G-S-K-A-G-F-I-R-I-F-E-R-L-G-I-G-Y-V-E-I-E-E-R-F-D-R-E-N-W-D-V-I-K-I-R-I-S-D-S-Q-L-A-K-K-T-E-L-L-N-L-I-I-R-K-Y-G-R-T-C-R-R-Y-T-F-E-V-I-T-K-E-T-V-S-I-Y-H-G-E-F-N-H-D-H-Q-S-F-Y-V-K-V-N"} +{"text": "### FUNCTION Required for the secretion of flagellin and expression of motility ### SEQUENCE -R-L-H-H-N-Q-F-A-I-R-G-G-Q-P-L-L-K-E-F-Y-L-L-M-V-D-F-F-F-I-R-S-L-I-S-A-H-I-L-K-V-G-L-I-T-E-D-D-V-I-D-I-F-Y-S-Y-H-A-F-R-Q-H-S-A-K-V-E-A-D-F-R-T-E-I-D-K-V-K-I-N-D-D-L-S-L-L-Q-L-L-V"} +{"text": "### FUNCTION May regulate sigma factor activity ### SEQUENCE -M-P-G-L-Q-L-K-K-R-P-L-S-R-Y-L-K-D-Y-K-H-G-Q-T-H-C-S-H-C-H-K-Q-L-D-R-M-A-L-V-F-R-G-Q-I-I-N-K-E-A-I-A-G-M-D-Q-P-I-D-D-Q-V-W-S-K-L-Q-H"} +{"text": "### FUNCTION Involved in plasmid stability ### SEQUENCE -M-A-N-V-T-V-R-N-L-P-D-E-V-H-R-A-L-R-V-R-A-A-M-H-G-R-S-T-E-A-E-I-R-D-I-L-E-T-T-V-R-P-P-E-R-V-K-L-G-S-L-L-A-S-I-A-H-E-A-G-G-L-T-D-A-E-A-E-H-F-N-Q-L-R-D-K-T-P-A-E-P-M-S-F-E"} +{"text": "### FUNCTION Probable toxic component of a type II toxin-antitoxin system It is not known which gene encodes its antitoxin ### SEQUENCE -M-R-E-R-A-V-G-S-K-G-S-F-P-I-G-I-A-E-L-Q-E-V-S-C-A-S-V-E-I-N-Q-P-L-L-L-A-D-L-R-S-D-G-M-L-R-M-R-I-P-T-D-A-A-R-A-A-S-H-E-L-G-K-Q-W-S-R-A-L-W-L-H-D-E-K-P-D-G-I-I-Y-D-S-R-L-N-G-E-A-N-T-A-L-F-D-R-A-L-P-K-L-N-V-K-S-S-G-P-L-L-D-F-R-D-E-V-A-Q-I-L-D-D-F-S-L-E-I-V"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system ### SEQUENCE -M-S-R-K-R-I-R-W-T-L-R-A-L-R-R-L-D-E-I-G-A-Y-I-E-K-D-D-P-D-A-A-A-R-V-V-A-R-I-G-T-A-V-D-A-L-A-E-Y-P-A-S-G-R-P-G-R-I-K-S-T-R-E-L-V-L-A-D-I-P-Y-I-I-P-Y-R-I-S-R-D-V-E-I-L-T-V-M-H-A-H-Q-Q-W-P-Q-V-L"} +{"text": "### FUNCTION Could be involved directly or indirectly in exopolysaccharide synthesis ### SEQUENCE -M-R-S-F-R-A-A-E-L-P-D-R-N-S-I-A-S-I-S-G-L-I-G-S-D-L-I-Q-M-I-R-F-D-D-M-H-S-L-F-V-G-E-E-A-L-R-V-G-L-T-A-F-T-I-F-D-G-Y-P-I-P-L-A-G-Q-I-A-L-L-G-G-D-G-S-K-P-Y-R-S-P-S-I-T-M-T-E-A-A-R-R-F-E-C-C-R-P-V-L-D-P-V-F-A-P-M-D-R-V-A-N-K-G-L-I-V-A-G-A-L-E-S-L-Q-V-R-I-D-R-R-S-P-V-L-L"} +{"text": "### FUNCTION RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA, but also in box C/D and box C'/D' sRNAs ### SEQUENCE -E-K-K-V-T-D-K-C-A-F-Y-G-V-P-L-C-K-V-P-D-R-Y-V-L-G-G-A-I-G-K-D-A-R-V-V-V-A-V-T-D-E-G-F-A-R-Q-L-Q-T-M-L-D-R-S-L-W-G"} +{"text": "### FUNCTION RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA, but also in box C/D and box C'/D' sRNAs ### SEQUENCE -M-N-E-G-N-R-Q-K-A-M-N-L-I-G-L-A-M-R-A-G-K-L-I-T-G-E-E-L-T-I-A-D-I-R-N-E-K-A-K-I-V-F-V-A-N-D-A-S-E-N-T-K-K-K-V-K-D-K-S-S-Y-Y-E-V-P-C-F-E-L-F-S-E-A-E-I-T-Q-M-I-G-K-P-R-K-V-F-G-I-V-D-N-G-F-A-K-K-T-K-E-L-I-E-G"} +{"text": "### FUNCTION Modulates the action of auxin, and may function as plant growth regulator that alters phytohormone responses ### SEQUENCE -M-K-F-L-C-W-Q-K-S-I-H-G-S"} +{"text": "### FUNCTION Modulates the action of auxin, and may function as plant growth regulator that alters phytohormone responses ### SEQUENCE -M-E-L-C-W-L-T-T-I-H-G-S"} +{"text": "### FUNCTION Modulates the action of auxin, and may function as plant growth regulator that alters phytohormone responses ### SEQUENCE -M-K-L-L-C-W-Q-K-S-I-H-G-S"} +{"text": "### FUNCTION Might be involved in Fe ### SEQUENCE -M-T-L-N-E-A-I-K-D-K-V-Y-E-I-V-E-I-A-N-C-D-E-A-L-K-K-R-F-L-S-F-G-I-H-E-G-V-Q-C-I-L-L-H-Y-S-M-K-K-A-T-L-S-V-K-I-N-R-I-Q-V-A-L-R-S-H-E-A-Q-Y-L-V-I-K-E-S-V"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-R-K-I-T-S-V-S-V-G-E-Q-L-D-S-F-I-T-R-M-V-Q-S-G-R-Y-G-S-A-S-E-V-M-R-S-A-L-R-L-L-E-Q-Q-E-S-R-D-E-A-V-R-N-A-V-I-E-G-L-E-S-G-E-S-S-M-T-L-R-D-I-A-A-E-R-K-Q-K-H-R-V"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-A-K-N-T-S-I-T-L-G-E-H-F-D-G-F-I-T-S-Q-I-Q-S-G-R-Y-G-S-A-S-E-V-I-R-S-A-L-R-L-L-E-N-Q-E-T-K-L-Q-S-L-R-Q-L-L-I-E-G-E-Q-S-G-D-A-D-Y-D-L-D-S-F-I-N-E-L-D-S-E-N-I-R"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-K-A-I-T-T-T-Q-A-K-D-H-L-D-E-L-I-N-A-V-I-S-D-L-E-P-T-I-V-S-N-N-Q-G-Q-Q-A-V-L-I-S-L-D-E-F-N-S-W-Q-E-T-L-Y-L-L-S-N-P-T-N-A-E-H-L-M-A-S-I-K-Q-A-E-T-G-Q-I-I-K-Q-K-L-P-D-L-L-E-L"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-N-N-N-N-V-Y-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-Q-A-E-G-R-P-V-D-I-Q-A-V-T-G-N-M-D-E-E-H-R-D-W-F-C-K-R-Y-A-L-Y-C-Q-Q-A-T-Q-A-K-K-L-E-L-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-L-L-L-S-M-I-S-R-C-L-I-L-I-I-L-C-Y-Q-R-Y-I-S-V-F-L-S-P-R-C-R-F-Y-P-T-C-S-H-Y-A-V-D-A-L-Y-T-F-G-L-L-K-G-L-L-L-I-A-K-R-I-L-K-C-H-P-F-H-S-G-G-L-N-S-I-S-I-K-T-K-S-K-R-E-Y"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -C-S-L-P-V-L-A-T-F-H-R-K-L-R-A-E-V-P-L-Q-N-R-L-E-D-N-D-R-A-P-W-L-L-A-R-R-L-L-A-E-S-Y-Q-Q-Q-F-Q-E-S-G-T"} +{"text": "### FUNCTION Absolutely required for transposition of IS1 ### SEQUENCE -M-A-S-V-S-I-S-C-P-S-C-S-A-T-D-G-V-V-R-N-G-K-S-T-A-G-H-Q-R-Y-L-C-S-H-C-R-K-T-W-Q-L-Q-F-T-Y-T-A-S-Q-P-G-T-H-Q-K-I-I-D-M-A-M-N-G-V-G-C-R-A-T-A-R-I-M-G-V-G-L-N-T-I-L-R-H-L-K-N-S-G-R-S-R"} +{"text": "### FUNCTION Could be involved in mycobactin synthesis ### SEQUENCE -M-S-T-N-P-F-D-D-D-N-G-A-F-F-V-L-V-N-D-E-D-Q-H-S-L-W-P-V-F-A-D-I-P-A-G-W-R-V-V-H-G-E-A-S-R-A-A-C-L-D-Y-V-E-K-N-W-T-D-L-R-P-K-S-L-R-D-A-M-A-E-D"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-I-S-N-V-T-E-A-L-S-N-F-T-R-C-Y-V-D-L-W-Q-K-E-T-G-A-P-P-A-S-R-E-L-Y-G-V-P-S-P-C-I-T-Q-T-G-D-N-I-V-Y-W-L-P-Q-P-F-P-L-E-E-K-L-N-S-V-E-V-A-L-D-I-Q-L-Q-P-A-I-H-D-F-Y-T-S-Q-L-A-G-D-M-T-V-T-F-E-G-Q-R-L-S-L-I-Q-V-W-S-E-D-D-F-I-R-L-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-A-F-I-A-T-M-E-S-D-D-M-G-I-I-S-L-C-N-L-T-G-E-V-I-L-E-Q-F-G-S-H-K-R-E-R-L-F-T-D-L-V-G-F-L-G-A-I-E-P-V-F-M-R"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-S-S-P-V-S-L-A-L-A-D-F-S-Q-R-F-Q-A-A-W-Q-A-Q-H-N-A-L-P-S-S-E-E-L-A-D-L-P-S-P-C-V-V-E-S-K-G-D-E-V-L-W-R-S-V-S-L-S-A-P-V-D-F-A-N-V-E-Q-A-I-E-L-T-L-H-D-D-I-K-A-F-Y-G-S-Q-L-S-A-D-M-T-A-T-W-E-G-N-E-L-T-L-L-Q-V-W-N-D-D-D-F-T-R-L-Q-E-N-I-L-G-H-L-V-T-Q-R-R-L-K-L-K-P-T-V-F-I-A-A-T-D-A-E-L-D-V-L-S-I-C-N-I-T-G-N-V-V-L-E-R-L-G-T-S-Q-R-D-V-L-A-E-N-V-T-E-F-L-T-K-L-Q-P-M-V"} +{"text": "### FUNCTION This protein is involved in the attenuation mechanism for the control of the expression of the his operon structural genes ### SEQUENCE -M-T-R-V-Q-F-K-H-H-H-H-H-H-H-P-D"} +{"text": "### FUNCTION This protein is involved in the attenuation mechanism for the control of the expression of the his operon structural genes ### SEQUENCE -M-T-R-V-Q-F-K-H-H-H-H-H-H-H-P-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-L-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-H-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-C-A-P-T-S-D-D-P-F-D-I-P-E-P-K-S-I-P-A-K-T-A-A-S-A-V-R-F-Y-Q-K-Y-L-S-G-L-K-M-G-S-T-C-R-F-D-P-V-C-S-T-Y-A-L-K-A-V-S-V-H-G-A-F-K-G-T-I-L-S-A-A-R-L-S-K-C-G-P-W-H-P-G-G-F-D-P-V-P-N-H-G-F-W-S-T-E-T-V-T"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-V-M-L-R-R-L-V-V-L-P-V-R-F-Y-Q-Y-C-I-S-P-L-F-P-P-A-C-R-Y-V-P-T-C-S-A-Y-T-A-E-A-V-M-R-H-G-V-M-R-G-L-W-L-A-A-R-R-I-L-R-C-H-P-W-C-A-G-G-H-D-P-V-P-P-V-P-P-Q-R-Y-P-S-A-Q-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-A-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-N-T-R-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-G-I-L-Y-I-I-G-I-Y-Q-R-Y-L-S-P-L-K-G-P-T-C-R-F-Y-P-S-C-S-R-Y-A-H-E-S-L-T-R-Y-G-L-V-K-G-L-W-L-T-T-I-R-I-L-K-C-H-P-F-H-P-G-G-V-D-P-V-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-K-L-L-I-G-L-V-N-V-Y-K-K-F-I-S-P-I-L-P-P-T-C-R-Y-Y-P-T-C-S-S-Y-M-I-D-A-L-K-K-H-G-A-I-L-G-L-I-M-G-L-A-R-I-L-R-C-N-P-F-I-K-G-G-V-D-P-V-P-D-Y-F-T-L-R-R-N-P-H-P-E-R-Y-E-D-E-I-I-A-Q-A-F-H-S-N-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-L-P-S-R-G-T-D-W-I-A-Q-V-L-R-L-P-R-N-A-G-R-G-L-I-W-L-Y-R-H-T-L-S-P-L-V-G-Y-N-C-R-H-Y-P-T-C-S-M-Y-G-D-E-A-I-R-K-F-G-L-W-A-G-G-W-M-T-L-A-R-L-L-R-C-Q-P-W-G-T-S-G-I-D-L-V-P-Q-T-A-P-S-R-A-R-W-Y-L-P-W-R-Y-A-R-W-R-G-V-N-A-P-P-P-D-V-A-E-P-C-G-C-G-S-H-S-Q-L-T-P-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-H-P-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-L-L-V-S-F-L-C-A-C-I-I-F-Y-Q-K-A-I-S-P-H-F-P-P-S-C-R-Y-E-P-T-C-S-Q-Y-A-I-E-S-I-K-K-Y-G-P-F-K-G-A-G-M-A-L-L-R-I-L-R-C-N-P-L-C-K-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-P-L-S-P-G-S-R-I-L-I-G-L-I-R-G-Y-Q-L-V-I-S-P-L-L-G-P-R-C-R-F-H-P-T-C-S-H-Y-G-I-E-A-L-R-R-F-G-M-I-K-G-S-W-L-T-L-K-R-V-L-K-C-H-P-L-N-S-G-G-D-D-P-V-P-P-K-L-D-D-N-R-E-H"} +{"text": "### FUNCTION This peptide is involved in the control mechanism of the synthesis of the macrolide-lincosamide-streptogramin B resistance protein It acts as a transcriptional attenuator ### SEQUENCE -M-T-H-S-M-R-L-R-F-P-T-L-N-Q"} +{"text": "### FUNCTION This peptide is involved in the control mechanism of the synthesis of the macrolide-lincosamide-streptogramin B resistance protein It acts as a transcriptional attenuator ### SEQUENCE -M-T-H-S-M-R-L-R-F-P-T-L-N-Q"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Repressor of the cell division arrest function of DgcN Prevents DgcN relocation to the midcell ### SEQUENCE -M-R-F-S-H-R-L-F-L-L-L-I-L-L-L-T-G-A-P-I-L-A-Q-E-P-S-D-V-A-K-N-V-R-M-M-V-S-G-I-V-S-Y-T-R-W-P-A-L-S-G-P-P-K-L-C-I-F-S-S-S-R-F-S-T-A-L-Q-E-N-A-A-T-S-L-P-Y-L-P-V-I-I-H-T-Q-Q-E-A-M-I-S-G-C-N-G-F-Y-F-G-N-E-S-P-T-F-Q-M-E-L-T-E-Q-Y-P-S-K-A-L-L-L-I-A-E-Q-N-T-E-C-I-I-G-S-A-F-C-L-I-I-H-N-N-D-V-R-F-A-V-N-L-D-A-L-S-R-S-G-V-K-V-N-P-D-V-L-M-L-A-R-K-K-N-D-G"} +{"text": "### FUNCTION Required for the use of extracellular DNA as a nutrient ### SEQUENCE -M-N-P-P-I-N-F-L-P-W-R-Q-Q-R-R-T-A-F-L-R-F-W-L-L-M-F-V-A-P-L-L-L-A-V-G-I-T-L-I-L-R-L-T-G-S-A-E-A-R-I-D-A-V-L-L-Q-A-E-Q-Q-L-A-R-S-L-Q-I-T-K-P-R-L-L-E-Q-Q-Q-L-R-E-Q-R-S-Q-R-Q-R-Q-R-Q-F-T-R-D-W-Q-S-A-L-E-A-L-A-A-L-L-P-E-H-A-W-L-T-T-I-S-W-Q-Q-G-T-L-E-I-K-G-L-T-T-S-I-T-A-L-N-A-L-E-T-S-L-R-Q-D-A-S-F-H-L-N-Q-R-G-A-T-Q-Q-D-A-Q-G-R-W-Q-F-E-Y-Q-L-T-R-K-V-S-D-E-H-V-L"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Neutralizes the activity of cognate toxin MbcT by blocking access to the toxin active site ### SEQUENCE -M-G-V-N-V-L-A-S-T-V-S-G-A-I-E-R-L-G-L-T-Y-E-E-V-G-D-I-V-D-A-S-P-R-S-V-A-R-W-T-A-G-Q-V-V-P-Q-R-L-N-K-Q-R-L-I-E-L-A-Y-V-A-D-A-L-A-E-V-L-P-R-D-Q-A-N-V-W-M-F-S-P-N-R-L-L-E-H-R-K-P-A-D-L-V-R-D-G-E-Y-Q-R-V-L-A-L-I-D-A-M-A-E-G-V-F-V"} +{"text": "### FUNCTION May play a regulatory role in sulfomenaquinone biosynthesis ### SEQUENCE -M-A-N-D-A-R-P-L-A-R-L-A-N-C-R-V-G-D-Q-S-S-A-T-H-A-Y-T-V-G-P-V-L-G-V-P-P-T-G-G-V-D-L-R-Y-G-G-R-A-G-I-G-R-S-E-T-V-T-D-H-G-A-V-G-R-R-Y-H-Q-P-C-A-G-Q-I-R-L-S-E-L-R-V-T-I-L-L-R-C-E-T-L-C-E-T-A-Q-L-L-R-C-P-P-L-P-C-D-C-S-T-P-L"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-S-I-S-A-S-E-A-R-Q-R-L-F-P-L-I-E-Q-V-N-T-D-H-Q-P-V-R-I-T-S-R-A-G-D-A-V-L-M-S-A-D-D-Y-D-A-W-Q-E-T-V-Y-L-L-R-S-P-E-N-A-R-R-L-M-E-A-V-A-R-D-K-A-G-H-S-A-F-T-K-S-V-D-E-L-R-E-M-A-G-G-E-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-D-I-A-G-R-S-L-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-Q-K-L-G-I-P-A-T-R-I-P-L-H-G-R-I-E-V-D-E-P-Y-V-L-I-L-P-T-Y-G-G-G-R-A-N-P-G-L-D-A-G-G-Y-V-P-K-Q-V-I-A-F-L-N-N-D-H-N-R-A-Q-L-R-G-V-I-A-A-G-N-T-N-F-G-A-E-F-C-Y-A-G-D-V-V-S-R-K-C-S-V-P-Y-L-Y-R-F-E-L-M-G-T-E-D-D-V-A-A-V-R-T-G-L-A-E-F-W-K-E-Q-T-C-H-Q-P-S-L-Q-S-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-P-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-Q-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-K-Q-T-N-N-L-I-T-E-R-T-H-P-C-H-K-P-M-R-H-T-S-H"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-A-Y-K-H-I-G-V-A-I-S-G-N-E-E-D-A-L-L-V-N-K-A-L-E-L-A-R-H-N-D-A-H-L-T-L-I-H-I-D-D-G-L-S-E-L-Y-P-G-I-Y-F-P-A-T-E-D-I-L-Q-L-L-K-N-K-S-D-N-K-L-Y-K-L-T-K-N-I-Q-W-P-K-T-K-L-R-I-E-R-G-E-M-P-E-T-L-L-E-I-M-Q-K-E-Q-C-D-L-L-V-C-G-H-H-H-S-F-I-N-R-L-M-P-A-Y-R-G-M-I-N-K-L-S-A-D-L-L-I-V-P-F-I-D-K"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-A-Y-K-H-I-G-V-A-I-S-G-N-E-E-D-A-L-L-V-N-K-A-L-E-L-A-R-H-N-D-A-H-L-T-L-I-H-I-D-D-G-L-S-E-L-Y-P-G-I-Y-F-P-A-T-E-D-I-L-Q-L-L-K-N-K-S-D-N-K-L-Y-K-L-T-K-N-I-Q-W-P-K-T-K-L-R-I-E-R-G-E-M-P-E-T-L-L-E-I-M-Q-K-E-Q-C-D-L-L-V-C-G-H-H-H-S-F-I-N-R-L-M-P-A-Y-R-G-M-I-N-K-L-S-A-D-L-L-I-V-P-F-I-D-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-S-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-A-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-D-I-L-E-K-Y-T-D-D-A-F-L-Q-E-K-I-S-I-L-S-S-I-D-N-R-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-S-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-A-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-D-I-L-E-K-Y-T-D-D-A-F-L-Q-E-K-I-S-I-L-S-S-I-D-N-R-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle ### SEQUENCE -M-N-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle ### SEQUENCE -M-N-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-G-K-N-T-S-F-V-L-D-E-H-Y-S-A-F-I-D-G-E-I-A-A-G-R-Y-R-S-A-S-E-V-I-R-S-A-L-R-L-L-E-D-R-E-T-Q-L-R-A-L-R-E-A-L-E-A-G-E-R-S-G-S-S-T-P-F-D-F-D-G-F-L-G-R-K-R-A-D-A-S-R-G-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-F-L-L-S-K-L-L-L-G-L-I-R-F-Y-Q-Y-C-I-S-P-L-I-P-P-R-C-R-Y-T-P-T-C-S-Q-Y-A-V-E-A-V-K-K-Y-G-A-F-K-G-G-R-L-A-I-K-R-I-A-R-C-H-P-F-G-G-H-G-H-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-F-L-L-S-K-L-L-L-G-L-I-R-F-Y-Q-Y-C-I-S-P-L-I-P-P-R-C-R-Y-T-P-T-C-S-Q-Y-A-V-E-A-V-K-K-Y-G-A-F-K-G-G-R-L-A-I-K-R-I-A-R-C-H-P-F-G-G-H-G-H-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-A-G-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-A-E-K-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-F-C-V-K-L-N-K-E-A-E-G-M-K-F-P-P-L-P-N-E-L-G-K-R-I-F-E-N-V-S-Q-E-A-W-A-A-W-T-R-H-Q-T-M-L-I-N-E-N-R-L-S-L-A-D-P-R-A-R-E-Y-L-A-Q-Q-M-E-Q-Y-F-F-G-D-G-A-D-A-V-Q-G-Y-V-P-Q"} +{"text": "### FUNCTION Plays a role for multiplication of the virus in different cell types ### SEQUENCE -M-G-V-Q-H-K-L-D-I-F-L-V-S-E-G-I-A-I-K-E-A-N-L-L-K-G-D-S-Y-G-C-T-I-K-I-K-L-D-K-E-K-T-F-K-F-V-I-V-L-E-P-E-W-I-D-E-I-K-P-I-Y-M-K-V-N-D-E-S-V-E-L-E-L-D-Y-K-D-A-I-K-R-I-Y-S-A-E-V-V-L-C-S-D-S-V-I-N-L-F-S-D-V-D-V-S-Y-T-C-E-Y-P-T-I-K-V-N-T-I-K-K-Y-Y-S-V-Q-N-R-G-M-T-Y-V-H-I-E-S-P-I-N-T-K-D-K-C-W-F-V-E-K-N-G-W-Y-E-D-R-T-H-S"} +{"text": "### FUNCTION Plays a role for multiplication of the virus in different cell types ### SEQUENCE -M-G-V-Q-H-K-L-D-I-F-L-V-S-E-G-I-A-I-K-E-A-N-L-L-K-G-D-S-Y-G-C-T-I-K-I-K-L-D-K-E-K-T-F-K-F-V-I-V-L-E-P-E-W-I-D-E-I-K-P-I-Y-M-K-V-N-D-E-S-V-E-L-E-L-D-Y-K-D-A-I-K-R-I-Y-S-A-E-V-V-L-C-S-D-S-V-I-N-L-F-S-D-V-D-V-S-Y-T-C-E-Y-P-T-I-K-V-N-T-I-K-K-Y-Y-S-V-Q-N-R-G-M-T-Y-V-H-I-E-S-P-I-N-T-K-D-K-C-W-F-V-E-K-N-G-W-Y-E-D-R-T-H-S"} +{"text": "### FUNCTION Inhibits antiviral activity induced by type I interferons Does not block signal transduction of IFN, but is important to counteract the host antiviral state induced by a pre-treatment with IFN ### SEQUENCE -M-G-I-Q-H-E-F-D-I-I-I-N-G-D-I-A-L-R-N-L-Q-L-H-R-G-D-N-Y-G-C-K-L-K-I-I-S-N-D-Y-K-K-L-K-F-R-F-I-I-R-P-D-W-S-E-I-D-E-V-K-G-L-T-V-F-A-N-N-Y-V-V-K-V-N-K-V-D-D-T-F-Y-Y-V-I-Y-E-A-V-I-H-L-Y-N-K-K-T-E-I-L-I-Y-S-D-D-E-K-E-L-F-K-H-Y-Y-P-Y-I-S-L-N-M-I-S-K-K-Y-K-V-K-E-E-N-Y-S-S-P-Y-I-E-H-P-L-I-P-Y-R-D-Y-E-S-M-D"} +{"text": "### FUNCTION Inhibits antiviral activity induced by type I interferons Does not block signal transduction of IFN, but is important to counteract the host antiviral state induced by a pre-treatment with IFN ### SEQUENCE -M-G-I-Q-H-E-F-D-I-I-I-N-G-D-I-A-L-R-N-L-Q-L-H-R-G-D-N-Y-G-C-K-L-K-I-I-S-N-D-Y-K-K-L-K-F-R-F-I-I-R-P-D-W-S-E-I-D-E-V-K-G-L-T-V-F-A-N-N-Y-V-V-K-V-N-K-V-D-D-T-F-Y-Y-V-I-Y-E-A-V-I-H-L-Y-N-K-K-T-E-I-L-I-Y-S-D-D-E-K-E-L-F-K-H-Y-Y-P-Y-I-S-L-N-M-I-S-K-K-Y-K-V-K-E-E-N-Y-S-S-P-Y-I-E-H-P-L-I-P-Y-R-D-Y-E-S-M-D"} +{"text": "### FUNCTION Could be part of an electron transfer system required for anaerobic carnitine reduction Could be a 3Fe-4S cluster-containing protein ### SEQUENCE -M-T-S-P-V-N-V-D-V-K-L-G-V-N-K-F-N-V-D-E-E-H-P-H-I-V-V-K-A-D-A-D-K-Q-A-L-E-L-L-V-K-A-C-P-A-G-L-Y-K-K-Q-D-D-G-S-V-R-F-D-Y-A-G-C-L-E-C-G-T-C-R-I-L-G-L-G-S-A-L-E-Q-W-E-Y-P-R-G-T-F-G-V-E-F-R-Y-G"} +{"text": "### FUNCTION Could be part of an electron transfer system required for anaerobic carnitine reduction Could be a 3Fe-4S cluster-containing protein ### SEQUENCE -M-T-S-P-V-N-V-D-V-K-L-G-V-N-K-F-N-V-D-E-E-H-P-H-I-V-V-K-A-D-A-D-K-Q-A-L-E-L-L-V-K-A-C-P-A-G-L-Y-K-K-Q-D-D-G-S-V-R-F-D-Y-A-G-C-L-E-C-G-T-C-R-I-L-G-L-G-S-A-L-E-Q-W-E-Y-P-R-G-T-F-G-V-E-F-R-Y-G"} +{"text": "### FUNCTION The ea10 gene protein is believed to be involved in the production of the Tro phenotype This phenotype is expressed when phages that possess a mutant cro gene and a thermolabile cI repressor gene are unable to propagate at restrictive temperatures This inability is correlated with the shutoff of host macromolecular synthesis ### SEQUENCE -M-S-N-I-K-K-Y-I-I-D-Y-D-W-K-A-S-I-E-I-E-I-D-H-D-V-M-T-E-E-K-L-H-Q-I-N-N-F-W-S-D-S-E-Y-R-L-N-K-H-G-S-V-L-N-A-V-L-I-M-L-A-Q-H-A-L-L-I-A-I-S-S-D-L-N-A-Y-G-V-V-C-E-F-D-W-N-D-G-N-G-Q-E-G-W-P-P-M-D-G-S-E-G-I-R-I-T-D-I-D-T-S-G-I-F-D-S-D-D-M-T-I-K-A-A"} +{"text": "### FUNCTION The ea10 gene protein is believed to be involved in the production of the Tro phenotype This phenotype is expressed when phages that possess a mutant cro gene and a thermolabile cI repressor gene are unable to propagate at restrictive temperatures This inability is correlated with the shutoff of host macromolecular synthesis ### SEQUENCE -M-S-N-I-K-K-Y-I-I-D-Y-D-W-K-A-S-I-E-I-E-I-D-H-D-V-M-T-E-E-K-L-H-Q-I-N-N-F-W-S-D-S-E-Y-R-L-N-K-H-G-S-V-L-N-A-V-L-I-M-L-A-Q-H-A-L-L-I-A-I-S-S-D-L-N-A-Y-G-V-V-C-E-F-D-W-N-D-G-N-G-Q-E-G-W-P-P-M-D-G-S-E-G-I-R-I-T-D-I-D-T-S-G-I-F-D-S-D-D-M-T-I-K-A-A"} +{"text": "### FUNCTION Required for the stabilization of DNA within the phage head and for attachment of tails onto the head during morphogenesis ### SEQUENCE -M-T-R-Q-E-E-L-A-A-A-R-A-A-L-H-D-L-M-T-G-K-R-V-A-T-V-Q-K-D-G-R-R-V-E-F-T-A-T-S-V-S-D-L-K-K-Y-I-A-E-L-E-V-Q-T-G-M-T-Q-R-R-R-G-P-A-G-F-Y-V"} +{"text": "### FUNCTION Stabilizes the phosphorylated form of DegU, leading to enhanced production of levansucrase, alkaline protease, and neutral protease ### SEQUENCE -M-D-D-K-D-L-K-L-I-L-H-K-T-F-I-E-I-Y-S-D-L-E-E-L-A-D-I-A-K-K-G-K-P-S-M-E-K-Y-V-E-E-I-E-Q-R-C-K-Q-N-I-L-A-I-E-I-Q-M-K-I-K"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Molecular chaperone required for IpgD stabilization and secretion ### SEQUENCE -M-E-D-L-A-D-V-I-C-R-A-L-G-I-P-L-I-D-I-D-D-Q-A-I-M-L-D-D-D-V-L-I-Y-I-E-K-E-G-D-S-I-N-L-L-C-P-F-C-A-L-P-E-N-I-N-D-L-I-Y-A-L-S-L-N-Y-S-E-K-I-C-L-A-T-D-D-E-G-G-N-L-I-A-R-L-D-L-T-G-I-N-E-F-E-D-V-Y-V-N-T-E-Y-Y-I-S-R-V-R-W-L-K-D-E-F-A-R-R-M-K-G-Y"} +{"text": "### FUNCTION C protein is one of the proteins involved in the production and packaging of viral single-stranded DNA ### SEQUENCE -M-R-K-F-D-L-S-L-R-S-S-R-S-S-Y-F-A-T-F-R-H-Q-L-T-I-L-S-K-T-D-A-L-D-E-E-K-W-L-N-M-L-G-T-F-V-K-D-W-F-R-Y-E-S-H-F-V-H-G-R-D-S-L-V-D-I-L-K-E-R-G-L-L-S-E-S-D-A-V-Q-P-L-I-G-K-K-S"} +{"text": "### FUNCTION Disorganizes the host nucleoid and inhibits replication, but without host DNA cleavage or degradation Only the architecture of the nucleoid is affected May act on the host chromosomal sequences that determine the structure of the nucleoid Binds to dsDNA but not to ssDNA ### SEQUENCE -M-K-Y-M-T-V-T-D-L-N-N-A-G-A-T-V-I-G-T-I-K-G-G-E-W-F-L-G-T-P-H-K-D-I-L-S-K-P-G-F-Y-F-L-V-S-K-L-D-G-R-P-F-S-N-P-C-V-S-A-R-F-Y-V-G-N-Q-R-S-K-Q-G-F-S-A-V-L-S-H-I-R-Q-R-R-S-Q-L-A-R-T-I-A-N-N-N-V-P-Y-T-V-F-Y-L-P-A-S-K-M-K-P-L-T-T-G-F-G-K-G-Q-L-A-L-A-F-T-R-N-H-H-S-E-Y-Q-T-L-E-E-M-N-R-M-L-A-D-N-F-K-F-V-L-Q-A-Y"} +{"text": "### FUNCTION Disorganizes the host nucleoid and inhibits replication, but without host DNA cleavage or degradation Only the architecture of the nucleoid is affected May act on the host chromosomal sequences that determine the structure of the nucleoid Binds to dsDNA but not to ssDNA ### SEQUENCE -M-K-Y-M-T-V-T-D-L-N-N-A-G-A-T-V-I-G-T-I-K-G-G-E-W-F-L-G-T-P-H-K-D-I-L-S-K-P-G-F-Y-F-L-V-S-K-L-D-G-R-P-F-S-N-P-C-V-S-A-R-F-Y-V-G-N-Q-R-S-K-Q-G-F-S-A-V-L-S-H-I-R-Q-R-R-S-Q-L-A-R-T-I-A-N-N-N-V-P-Y-T-V-F-Y-L-P-A-S-K-M-K-P-L-T-T-G-F-G-K-G-Q-L-A-L-A-F-T-R-N-H-H-S-E-Y-Q-T-L-E-E-M-N-R-M-L-A-D-N-F-K-F-V-L-Q-A-Y"} +{"text": "### FUNCTION Disorganizes the host nucleoid and inhibits replication, but without host DNA cleavage or degradation Only the architecture of the nucleoid is affected May act on the host chromosomal sequences that determine the structure of the nucleoid Binds to dsDNA but not to ssDNA ### SEQUENCE -M-K-Y-M-T-V-T-D-L-N-N-A-G-A-T-V-I-G-T-I-K-G-G-E-W-F-L-G-T-P-H-K-D-I-L-S-K-P-G-F-Y-F-L-V-S-K-L-D-G-R-P-F-S-N-P-C-V-S-A-R-F-Y-V-G-N-Q-R-S-K-Q-G-F-S-A-V-L-S-H-I-R-Q-R-R-S-Q-L-A-R-T-I-A-N-N-N-V-P-Y-T-V-F-Y-L-P-A-S-K-M-K-P-L-T-T-G-F-G-K-G-Q-L-A-L-A-F-T-R-N-H-H-S-E-Y-Q-T-L-E-E-M-N-R-M-L-A-D-N-F-K-F-V-L-Q-A-Y"} +{"text": "### FUNCTION This protein allows the phage to reside inactively in the chromosome of its host bacterium This lysogenic state is maintained by binding of regulatory protein C2 to the OR and OL operators, preventing transcription of proteins necessary for lytic development ### SEQUENCE -M-N-T-Q-L"} +{"text": "### FUNCTION No function has yet been ascribed to K protein ### SEQUENCE -M-S-R-K-I-I-L-I-K-Q-E-L-L-L-L-V-Y-E-L-N-R-S-G-L-L-A-E-N-E-K-I-R-P-I-L-A-Q-L-E-K-L-L-L-C-D-L-S-P-S-T-N-D-S-V-K-N"} +{"text": "### FUNCTION Controls the translation of a number of proteins by binding to their mRNA ### SEQUENCE -M-I-E-I-T-L-K-K-P-E-D-F-L-K-V-K-E-T-L-T-R-M-G-I-A-N-N-K-D-K-V-L-Y-Q-S-C-H-I-L-Q-K-K-G-L-Y-Y-I-V-H-F-K-E-M-L-R-M-D-G-R-Q-V-E-M-T-E-E-D-E-V-R-R-D-S-I-A-W-L-L-E-D-W-G-L-I-E-I-V-P-G-Q-R-T-F-M-K-D-L-T-N-N-F-R-V-I-S-F-K-Q-K-H-E-W-K-L-V-P-K-Y-T-I-G-N"} +{"text": "### FUNCTION Controls the translation of a number of proteins by binding to their mRNA ### SEQUENCE -M-I-E-I-T-L-K-K-P-E-D-F-L-K-V-K-E-T-L-T-R-M-G-I-A-N-N-K-D-K-V-L-Y-Q-S-C-H-I-L-Q-K-K-G-L-Y-Y-I-V-H-F-K-E-M-L-R-M-D-G-R-Q-V-E-M-T-E-E-D-E-V-R-R-D-S-I-A-W-L-L-E-D-W-G-L-I-E-I-V-P-G-Q-R-T-F-M-K-D-L-T-N-N-F-R-V-I-S-F-K-Q-K-H-E-W-K-L-V-P-K-Y-T-I-G-N"} +{"text": "### FUNCTION Controls the translation of a number of proteins by binding to their mRNA ### SEQUENCE -M-I-E-I-T-L-K-K-P-E-D-F-L-K-V-K-E-T-L-T-R-M-G-I-A-N-N-K-D-K-V-L-Y-Q-S-C-H-I-L-Q-K-K-G-L-Y-Y-I-V-H-F-K-E-M-L-R-M-D-G-R-Q-V-E-M-T-E-E-D-E-V-R-R-D-S-I-A-W-L-L-E-D-W-G-L-I-E-I-V-P-G-Q-R-T-F-M-K-D-L-T-N-N-F-R-V-I-S-F-K-Q-K-H-E-W-K-L-V-P-K-Y-T-I-G-N"} +{"text": "### FUNCTION Controls the translation of a number of proteins by binding to their mRNA ### SEQUENCE -M-I-E-I-T-L-K-K-P-E-D-F-L-K-V-K-E-T-L-T-R-M-G-I-A-N-N-K-D-K-V-L-Y-Q-S-C-H-I-L-Q-K-K-G-L-Y-Y-I-V-H-F-K-E-M-L-R-M-D-G-R-Q-V-E-M-T-E-E-D-E-V-R-R-D-S-I-A-W-L-L-E-D-W-G-L-I-E-I-V-P-G-Q-R-T-F-M-K-D-L-T-N-N-F-R-V-I-S-F-K-Q-K-H-E-W-K-L-V-P-K-Y-T-I-G-N"} +{"text": "### FUNCTION Involved in the down-regulation of lcrGVH transcription in the presence or absence of calcium and is necessary for lcrG protein expression in the absence of calcium Plays an important role in the regulation of the low-calcium response ### SEQUENCE -M-M-A-D-P-L-I-P-W-L-T-E-H-G-L-V-C-H-P-H-T-L-S-G-T-P-I-S-L-G-S-A-F-Q-L-A-G-L-K-L-A-W-R-V-E-I-E-Q-R-R-V-W-I-V-L-I-Q-R-V-E-Q-R-R-G-L-K-N-P-F-A-A-L-Y-M-L-A-N-A-A-R-A-V-L-G-P-D-Y-Y-L-Y-G-N-V-D-V-L-A-G-S-S-L-S-T-Q-R-L-A-H-F-Y-R-R-W-T-G-A-K-E-L-S-T-G-W-F-S-L-K-V-S-Q-V-I-T-L-S-N-M-K-K-R-Q-N-N-G-F-A"} +{"text": "### FUNCTION May play an essential role in dissimilatory sulfite reduction ### SEQUENCE -M-A-D-Y-T-E-E-D-K-Q-K-V-L-A-Q-L-S-K-K-T-W-K-I-P-E-L-A-K-I-L-K-M-D-K-K-V-V-K-K-I-V-Q-D-L-I-N-E-G-V-A-G-Y-W-S-S-G-S-T-T-Y-V-A-T-K-E-Y-I-E-E-L-E-K-K-R-A-E-G"} +{"text": "### FUNCTION Involved in the maturation of iron-sulfur proteins May function as a Fe-S cluster carrier ### SEQUENCE -M-E-E-A-L-K-E-N-I-M-G-A-L-E-Q-V-V-D-P-E-L-G-V-D-I-V-N-L-G-L-V-Y-D-V-D-M-D-E-D-G-L-T-H-I-T-M-T-L-T-S-M-G-C-P-L-A-P-I-I-V-D-E-V-K-K-A-L-A-D-L-P-E-V-K-D-T-E-V-H-I-V-W-N-P-P-W-T-R-D-K-M-S-R-Y-A-K-I-A-L-G-I-Q"} +{"text": "### FUNCTION Required for transcription of the phage late genes ### SEQUENCE -M-A-H-Y-F-G-G-K-S-F-Y-L-P-A-G-D-K-I-K-E-A-L-R-D-A-Q-I-Y-Q-E-F-N-G-K-N-V-P-D-L-I-K-K-Y-R-L-S-E-S-T-I-Y-A-I-L-R-N-Q-R-T-L-Q-R-K-R-H-Q-M-D-F-N-F-S"} +{"text": "### FUNCTION Might take part in the signal recognition particle ### SEQUENCE -M-N-Q-T-K-L-N-Q-R-L-K-Q-Q-Q-L-F-D-I-Y-G-E-L-L-T-K-R-Q-A-C-Y-F-N-E-Y-I-N-L-D-L-S-M-Q-E-I-A-D-K-Y-Q-V-K-K-S-S-I-H-Q-H-I-K-T-C-N-L-I-F-N-R-F-E-A-K-L-Q-L-F-K-K-Q-Q-L-R-L-K-L-Y-E-K-I-T-D-P-Q-L-R-E-Q-L-I-K-L-R"} +{"text": "### FUNCTION The middle section of a putative type I restriction enzyme that if reconstituted might recognize 5'-GAN ### SEQUENCE -M-S-D-A-L-D-D-E-N-V-L-C-F-R-Y-K-S-Y-Y-I-K-D-D-G-S-R-I-D-T-L-N-E-E-R-I-K-H-I-V-D-F-T-L-D-K-Y-L-D-A-T-Q-N-T-P-K-F-D-N-F-E-N-P-V-K-E-G-F-N-S-I-F-A-C-E-S-K-E-A-A-I-E-Y-Y-K-E-F-K-K-Q-I-E-Q-K-K-L-P-I-K-I-A-S-I-I-A-Q-T-K-V-V-M-N-K-K-L-V"} +{"text": "### FUNCTION Corresponds to the N-terminus of a putative G subtype type II restriction/methylase subunit ### SEQUENCE -M-K-F-K-L-N-F-H-E-K-I-N-Q-K-D-C-W-Q-S-L-I-D-H-K-E-R-S-Y-S-L-D-F-V-N-N-T-E-K-E-L-P-L-I-Y-G-Y-E-V-K-D-F-E-N-H-G-V-K-I-G-Y-T-T-C-K-P-S-D-K-I-Q-S-A-I-E-E-R-I-L-S-Q-E-K-E-F-R-F-L-D-E-N-I-E-K-I-E-E-V-K-V-I-F-W-A-I-A-I-N-E-K-D-E-S-F-K-D-Y-S-L-H-S-F-I-K-E-K-N-L-L-K-E-S-Q-A-G-G-E-W-F-I-V-D-E-N-K-D-K-F-E-Y-L-S-Q-I-F-R-Q-F-R-A-P-S-L-F-K-K"} +{"text": "### FUNCTION Overlapping regulatory peptide whose translation enables hokB expression ### SEQUENCE -M-N-L-A-I-Q-I-L-A-S-Y-P-P-S-G-K-E-K-G-Y-E-A-Q-P-S-G-G-V-S-A-H-Y-L-H-Y-D-S-D-I-H-T-P-D-P-T-N-A-L-R-T-A-V-P-G-R"} +{"text": "### FUNCTION Possible component of hydrogenase 4 ### SEQUENCE -M-T-E-E-C-G-E-I-V-F-W-T-L-R-K-K-F-V-A-S-S-D-E-M-P-E-H-S-S-Q-V-M-Y-Y-S-L-A-I-G-H-H-V-G-V-I-D-C-L-N-V-A-F-R-C-P-L-T-E-Y-E-D-W-L-A-L-V-E-E-E-Q-A-R-R-K-M-L-G-V-M-T-F-G-E-I-V-I-D-A-S-H-T-A-L-L-T-R-A-F-A-P-L-A-D-D-A-T-S-V-W-Q-A-R-S-I-Q-F-I-H-L-L-D-E-I-V-Q-E-P-A-I-Y-L-M-A-R-K-I-A"} +{"text": "### FUNCTION Required for mitochondrial inner membrane peptidase function ### SEQUENCE -M-A-P-P-T-K-I-L-G-L-D-T-Q-Q-R-M-L-Q-R-G-E-N-C-S-L-K-S-L-V-Q-N-E-C-A-F-N-G-N-D-Y-V-C-T-P-F-K-R-L-F-E-Q-C-M-V-K-D-G-R-V-L-N-I-E-V-T-N-L-N-T-N-R"} +{"text": "### FUNCTION Not known, part of the enterotoxin complex ### SEQUENCE -X-T-Q-Q-E-G-M-D-I-S-S-S-L-X-K"} +{"text": "### FUNCTION Involved in etamycin biosynthesis ### SEQUENCE -M-L-D-G-V-V-A-R-P-Q-E-X-A-A-R-Y-Y-A-A-G-Y"} +{"text": "### FUNCTION Morphogenetically active peptide Active in foot development ### SEQUENCE -E-E-L-R-P-E-V-L-P-D-V-S-E"} +{"text": "### FUNCTION Start or boost ecdysteroid synthesis in testis of larvae and pupae ### SEQUENCE -I-S-D-F-D-E-Y-E-P-L-N-D-A-D-N-N-E-V-L-D-F"} +{"text": "### FUNCTION Stimulates synthesis of ecdysteroid in the testes of larvae and pupae ### SEQUENCE -I-S-A-L-F-D-E-Y-E-P-L-N-D-A-D"} +{"text": "### FUNCTION Stimulates synthesis of ecdysteroid in the testes of larvae and pupae ### SEQUENCE -S-E-L-T-V-E-D-V-E-P-L-N-N-A-D-K-N-K-V-V-I-X-I"} +{"text": "### FUNCTION Stimulates synthesis of ecdysteroid in the testes of larvae and pupae ### SEQUENCE -I-A-I-F-N-A-Y-T-P-L-P-F-A-D"} +{"text": "### FUNCTION Stimulates synthesis of ecdysteroid in the testes of larvae and pupae ### SEQUENCE -S-A-I-D-P-N-P-D-T-P-D-S-E"} +{"text": "### FUNCTION Antibacterial activity against several lactic acid bacteria, Listeria, Streptococci, etc ### SEQUENCE -G-M-S-G-Y-I-Q-G-I-P-D-F-L-K-G-Y-L-H-G-I-S-A-A-N-K-H-K-K-G-R-L"} +{"text": "### FUNCTION May mediate relaxation of depolarized colon tonus It binds iodocyanopindolol and SM-11044 ### SEQUENCE -F-V-V-F-I-L-A-D-P-A-R-Y-F-Q-F-Y-F-P-X-F-F-Q-H-R"} +{"text": "### FUNCTION Major component of the pollen coat ### SEQUENCE -A-P-L-T-N-E-Y-L-N-H-L-C-H-K-C"} +{"text": "### FUNCTION Is associated with lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell ### SEQUENCE -A-Q-G-D-N-P-D-K-D-T-D-G-N"} +{"text": "### FUNCTION May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast ### SEQUENCE -A-E-S-E-A-G-D-A-S-P-L-V-T-E-V-L-I-G-S-P-P-G-Y-V-G-Y-T-E-G-G"} +{"text": "### FUNCTION May play a structural role in the elaioplast, a tapetum-specific plastidial lipid organelle ### SEQUENCE -V-I-D-V-N-D-E-W"} +{"text": "### FUNCTION Lectin and alpha-amylase inhibitor Acts as a defensive protein against insects ### SEQUENCE -X-X-X-G-L-X-I-V-D-A-F-V-Q-P-N-L-I-L-Q-G-D-A-K-V-E-D-N-G-X-L"} +{"text": "### FUNCTION Structural component of the virion ### SEQUENCE -M-D-L-S-F-T-L-S-V-V-T-A"} +{"text": "### FUNCTION Structural component of the virion ### SEQUENCE -M-E-F-G-N-L-T-N-L-D-V-A"} +{"text": "### FUNCTION Structural component of the virion ### SEQUENCE -V-A-R-G-G-K-T-K-G-R-R-G"} +{"text": "### FUNCTION Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues ### SEQUENCE -V-T-C-S-P-V-Q-L-S-P-C-L-G-P-I-N-S-G-A-P-S-P-T-T-C-C-Q-K-L-R-E-Q-R-P-C-L-C-G-Y-L-K-N-P-S-L-R-Q-Y-V-N-S-P-N-A-R-K-L-A-S-N-C-G-V-P-V-P-Q-C"} +{"text": "### FUNCTION Inhibitor of the proliferation of hepatic stellate cells Also inhibits the growth of bovine endothelial cells and 3T6 fibroblasts ### SEQUENCE -A-E-P-V-E-P-W-S"} +{"text": "### FUNCTION Suppresses expansion of husk leaf blades ### SEQUENCE -D-A-Q-E-X-K-R-V-L-G-Q-L-H-G-G-P-F-S-A-S-A-K-Y-F-G-Q-A-H-G-G-X-E-K"} +{"text": "### FUNCTION Promotes expansion of husk leaf blades ### SEQUENCE -X-X-G-A-A-A-K-G"} +{"text": "### FUNCTION Has antioxidant activity Inhibits cyclooxygenase-2 and thromboxane A2 synthase ### SEQUENCE -D-E-D-N-V-L-L-T"} +{"text": "### FUNCTION This protein is one of the different antigenic serotypes of protein M Protein M is closely associated with virulence of the bacterium and can render the organism resistant to phagocytosis ### SEQUENCE -N-H-Q-L-T-Q-E-N-E-R-L-T-Q-K"} +{"text": "### FUNCTION May be involved in transporting molecules across the outer membrane ### SEQUENCE -D-E-A-V-V-H-D-S-Y-A-F-D-K-N-Q-L-I-P-V-G-A-R-A-E"} +{"text": "### FUNCTION Possible mediator for cell division in the blooming process ### SEQUENCE -A-E-Y-D-V-S-D-A-D-I-E-A-F-Y-Q"} +{"text": "### FUNCTION Possible mediator for cell division in the blooming process ### SEQUENCE -A-E-Y-D-V-S-D-A-D-I-E-A-F-Y-Q-X-X-T-M-T-W"} +{"text": "### FUNCTION Possible mediator for cell division in the blooming process ### SEQUENCE -A-E-Y-D-V-S-D-A-D-I-E-A-F-Y-Q"} +{"text": "### FUNCTION Possible 'checkpoint' protein for cell division in the blooming process ### SEQUENCE -V-S-A-E-Y-L-E-R-Q-G-P-K-D-D-X-D-C-F-D-D"} +{"text": "### FUNCTION Has antiviral activity against tobacco mosaic virus and antitumor activity ### SEQUENCE -N-R-D-V-A-A-C-A-R-F-I-D-D-F-C-D-T-L-T-P-N-I-Y-R-P-R-D-N-G-Q-R-C-Y-A-V-N-G-H-R-C-D-F-T-V-F-N-T-N-N-G-G-N-P-I-R-A-S-T-P-N-C-K-T-V-L-R-T-A-A-N-R-C-P-T-G-G-R-G-K-I-N-P-N-A-P-F-L-F-A-I-D-P-N-D-G-D-C-S-T-N-F"} +{"text": "### FUNCTION Has antifungal activity against Bcinerea, Foxysporum and Marachidicola Inhibits cell-free translation in rabbit reticulocyte lysate system Does not have mitogenic and anti-HIV-1 reverse transcriptase activities ### SEQUENCE -G-V-G-Y-K-V-V-V-T-T-T-A-A-A-D-D-D-D-V-V"} +{"text": "### FUNCTION Has antifungal activity against Bcinerea, Foxysporum and Marachidicola Inhibits cell-free translation in rabbit reticulocyte lysate system ### SEQUENCE -P-Q-R-G-E-G-G-R-A-G-N-L-L-R-E-E-Q-E-I"} +{"text": "### FUNCTION Exerts antifungal activity against Foxysporum and Marachidicola, with an IC reverse transcriptase ### SEQUENCE -K-T-C-E-N-L-A-D-D-Y"} +{"text": "### FUNCTION Has antifungal activity against Foxysporum and Marachidicola ### SEQUENCE -A-T-R-V-V-Y-C-N-R-R-S-G-S-V-V-G-G-D-D-T-V-Y-Y-E-G"} +{"text": "### FUNCTION Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide The H form is known to activate a number of cytosolic enzymes ### SEQUENCE -M-I-A-P-I-F-A-E-L-A-K-T-V-G-A-D-K-D-G-L-P-T-L-V-A-K"} +{"text": "### FUNCTION May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast ### SEQUENCE -G-S-G-F-V-A-V-E-I-P-F-T-P-R-V-L-E-L-S-L-E-E-A-R-V-L-E-N-L-G-A-D-P-S-N-I-R-F-Q-P-V-K-V-P-E-P-S-V-D-E-T-I-Q-I-L-K-F-L-P-D-K-A-I-D-L-I-D-E-A-G-S-R"} +{"text": "### FUNCTION Chaperone ### SEQUENCE -S-T-A-G-D-T-H-L-G-G-E-D-F"} +{"text": "### FUNCTION Is associated with a DNA binding complex to bind to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes ### SEQUENCE -L-A-E-Q-A-E-R-Y-E-E-M-V-E-F-M-E-K"} +{"text": "### FUNCTION Probable receptor for the plant growth-promoting hormone auxin ### SEQUENCE -K-G-D-I-M-V-F-P-R"} +{"text": "### FUNCTION Inhibitor of shell growth ### SEQUENCE -E-C-N-I-G-D-I-C-V-V-H-G-D-C-S-E-C-K-C-S-D-G-R-A-A-K-C-D-R-E-H-G-E-P-P-H-C-S-C-S-H-R"} +{"text": "### FUNCTION Acts as a storage protein ### SEQUENCE -A-V-T-S-S-V-A-D-T-T-T-V-V-R-D-D-F"} +{"text": "### FUNCTION Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase ### SEQUENCE -G-L-A-Y-D-I-S-D-D-Q-Q-D-I-T-R-M-G-I-N-P-I-M-M-S-A-G-E-L-E-S-G-N-A-G-E-P-A-K-M-C-C-L-F-I-N-D-L-D-A-G-A-G-R-I-G-V-C-T-G-I-F-R"} +{"text": "### FUNCTION Binds pheromones that are released from drying urine of males These pheromones affect the sexual behavior of females ### SEQUENCE -N-N-V-D-K-L-N-G-D-W"} +{"text": "### FUNCTION Lectin specific for corefucosylated N-glycans Inhibits platelet aggregation ### SEQUENCE -F-G-P-G-C-G-P-S-T-F-S-C-T-S-P-Q-K-I-L-P-G-S-S-V-S-F-P-S-G-Y-S-S-I-Y-L-T-T-E-S-G-S-A-S-V-Y-L-D-R-P-D-G-F-W-V-G-G-A-D-S-R-G-C-S-N-F-G-G-F-N-G-N-G-D-S-K-V-G-N-W-G-D-V-P-V-A-A-W-A-C-N"} +{"text": "### FUNCTION Required for the transport of riboflavin to the developing oocyte ### SEQUENCE -K-K-Y-S-C-L-E-G-E-T-H-K-L-K-P-S-P-E-P-N-M-Q-E-C-T-L-Y-S-G-S-S-C-C-Y-A"} +{"text": "### FUNCTION Molecular chaperone Has ATPase activity ### SEQUENCE -E-L-V-S-N-A-S-D-A-L-D-K-L-R"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -V-V-D-I-V-D-T-F-R-N-N-I-Q-G-A-T-K"} +{"text": "### FUNCTION This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis ### SEQUENCE -R-X-S-D-K-P-L-R-I-G-G-I-G-T-V-P-V-G-R"} +{"text": "### FUNCTION Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins ### SEQUENCE -E-L-L-S-E-I-N-R"} +{"text": "### FUNCTION Has a function in the early stage of chloroplast development and palisade cell morphogenesis ### SEQUENCE -A-W-V-D-W-E-D-Q-I-L-Q-D-T-V-P-L-V-N-F-V-R-M-I"} +{"text": "### FUNCTION Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells Essential component of cell cytoskeleton ### SEQUENCE -L-A-Y-V-A-L-D-Y-E-Q-E-L-E-T-A-K-S-Y-E-L-P-D-G-Q-V-I-T-I-G-A-E-R"} +{"text": "### FUNCTION May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule ### SEQUENCE -V-F-E-I-A-P-S-A-K"} +{"text": "### FUNCTION Antibacterial protein ### SEQUENCE -V-F-G-T-L-G-S-T-D-D-S-L-F-G-R-Y-K-Q-D-I-F-N-D-H-R-G-H-L-Q-G-Q-A-Y-G-S-R"} +{"text": "### FUNCTION Inhibits insect alpha-amylases ### SEQUENCE -S-G-L-L-M-N-F-G-E-Q-H-V-N-V-A-Q"} +{"text": "### FUNCTION Inhibits insect alpha-amylases ### SEQUENCE -S-G-G-E-M-S-N-M-G-H-S-M-E-E"} +{"text": "### FUNCTION Inhibits insect alpha-amylases ### SEQUENCE -S-G-G-G-N-V-I-M-N-Q-M-N-K-R-N-H-A-K-D"} +{"text": "### FUNCTION Inhibits insect alpha-amylases ### SEQUENCE -S-G-G-G-K-E-A-A-E-T-F-N-R-V-E-S-H-P-R-P-D-A"} +{"text": "### FUNCTION May play a role in the developmental transition from cell proliferation to cell differentiation during neurogenesis ### SEQUENCE -T-K-S-P-D-C-G-G-I-L-S-P-S-G-L-S-Y-F-A"} +{"text": "### FUNCTION May possess antifungal activity against Bcinerea ### SEQUENCE -E-A-L-Y-N-S-E-D-L-Y-E-E-T-S-D-S-D-D"} +{"text": "### FUNCTION May possess antifungal activity against Bcinerea ### SEQUENCE -S-P-P-E-A-A-Y-G-P-G-N-T-N-S-D-S-G-D-K"} +{"text": "### FUNCTION Like parvalbumins, SCPs seem to be more abundant in fast contracting muscles, but no functional relationship can be established from this distribution ### SEQUENCE -V-A-T-V-S-L-P-R"} +{"text": "### FUNCTION Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity ### SEQUENCE -K-G-F-M-T-P-E-R-A-A-E-F-N-F-R"} +{"text": "### FUNCTION Plays a role for multiplication of the virus in different cell types ### SEQUENCE -M-H-V-F-Y-A-V-I-D-N-T-I-D-L-E-C-L-T-L-H-K-G-V-E-Y-G-C-K-L-Q-L-I-S-K-N-T-K-T-V-N-I-K-C-I-T-E-V-Y-Y-S-D-H-L-L-K-P-L-M-A-Y-V-N-D-K-L-I-Q-L-D-R-K-K-L-R-H-K-I-V-Y-S-I-D-L-T-L-Y-D-E-V-T-N-M-L-V-C-S-N-M-D-P-D-L-I-D-R-Y-Y-A-K-I-C-L-D-F-D-N-N-V-Y-T-V-K-D-K-N-Y-T-N-A-V-I-E-Y-P-V-V-C-N-F-R-R-Y-S-E-S-D-S-D-S-D-V-D-D-R-A-E-L-H-K-R-N-N-D-S-D-S-D-D-Y-T"} +{"text": "### FUNCTION May play a role in infectivity ### SEQUENCE -M-E-L-P-L-P-E-D-V-A-S-V-L-Y-L-T-P-L-A-A-V-R-E-V-N-L-W-N-G-A-P-P-P-Y-S-M-L-Q-L-W-A-R-V-D-H-A-W-A-K-D-R-V-G-R-S-Y-P-T-R-K-S-Y-F-K-S-T-R-L-L-P-R-T-L-Y-R-Q-Y-Q-S-Y-R-D-C-Q-C-L-Q-E-T-S-P-F-T-R-E-V-H-H-T-C-V-Q-L-D-P-L-S-P-S-T-D-G-E-H-S-P-S-S-G-S-P-A-V-L-R-Q-H-R-E-I-W-F"} +{"text": "### FUNCTION Peptide chaperone involved in the biosynthesis of the enzyme cofactor mycofactocin Binds MftA and MftC with high affinity, and is essential for MftC activity on MftA, likely via the formation of a ternary complex ### SEQUENCE -M-W-G-L-L-T-V-P-A-P-A-Q-A-R-R-A-D-S-S-E-F-D-P-D-R-G-W-R-L-H-P-Q-V-A-V-R-P-E-P-F-G-A-L-L-Y-H-F-G-T-R-K-L-S-F-L-K-N-R-T-I-L-A-V-V-Q-T-L-A-D-Y-P-D-I-R-S-A-C-R-G-A-G-V-D-D-C-D-Q-D-P-Y-L-H-A-L-S-V-L-A-G-S-N-M-L-V-P-R-Q-T-T"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapB14 ### SEQUENCE -M-I-R-N-L-P-E-G-T-K-A-A-L-R-V-R-A-A-R-H-H-H-S-V-E-A-E-A-R-A-I-L-T-A-G-L-L-G-E-E-V-P-M-P-V-L-L-A-A-D-S-G-H-D-I-D-F-E-P-E-R-L-G-L-I-A-R-T-P-Q-L"} +{"text": "### FUNCTION Displays ATPase and GTPase activities ### SEQUENCE -W-P-P-L-H-P-L-Y-R-T-D-L-S-L-E-A-A-I-E-E-E-A-N-R-L-D-P-L-V-Q-Q-A-N-L-L-I-D-T-A-A-L-S-T-H-E-L-A-E-R-L-R-E-F-L-S-G-H-S-D-K-E-L-K-I-V-V-E-S-F-G-F-K-Y-G-I-P-L-D-A-D-Y-V-F-D-V-R-F-L-P-N-P-H-W-N-Q-G-L-R-P-L-T-G-L-D-D-E-V-A-N-S"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-T-P-T-A-C-A-T-V-S-T-M-T-S-V-G-V-R-A-L-R-Q-R-A-S-E-L-L-R-R-V-E-A-G-E-T-I-E-I-T-D-R-G-R-P-V-A-L-L-S-P-L-P-Q-G-G-P-Y-E-Q-L-L-A-S-G-E-I-E-R-A-T-L-D-V-V-D-L-P-E-P-L-D-L-D-A-G-V-E-L-P-S-V-T-L-A-R-L-R-E-H-E-R"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-Q-L-G-R-K-V-T-S-H-H-D-I-D-R-F-G-V-A-S-T-A-D-E-S-V-Y-R-P-L-P-P-R-L-R-L-A-Q-V-N-L-S-R-R-R-C-R-T-Q-S-D-M-Y-K-S-R-F-S-E-C-T-V-Q-S-V-D-V-S-V-T-E-L-R-A-H-L-S-D-W-L-D-R-A-R-A-G-G-E-V-V-I-T-E-R-G-I-P-I-A-R-L-A-A-L-D-S-T-D-T-L-E-R-L-T-A-E-G-V-I-G-K-A-T-A-Q-R-P-V-A-A-G-R-P-R-P-R-P-Q-R-P-V-S-D-R-V-S-D-Q-R-R"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-N-E-V-S-I-R-T-L-N-Q-E-T-S-K-V-L-A-R-V-K-R-G-E-E-I-N-L-T-E-R-G-K-V-I-A-R-I-I-P-A-S-A-G-P-L-D-S-L-I-S-T-G-S-V-Q-P-A-R-V-H-G-P-A-P-R-P-T-I-P-M-R-G-G-L-D-S-G-T-L-L-E-R-M-R-A-E-E-R-Y"} +{"text": "### FUNCTION Probable antitoxin component of a probable type II toxin-antitoxin ### SEQUENCE -M-S-E-V-A-S-R-E-L-R-N-D-T-A-G-V-L-R-R-V-R-A-G-E-D-V-T-I-T-V-S-G-R-P-V-A-V-L-T-P-V-R-P-R-R-R-R-W-L-S-K-T-E-F-L-S-R-L-R-G-A-Q-A-D-P-G-L-R-N-D-L-A-V-L-A-G-D-T-T-E-D-L-G-P-I-R"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-T-R-R-L-R-V-H-N-G-V-E-D-D-L-F-E-A-F-S-Y-Y-A-D-A-A-P-D-Q-I-D-R-L-Y-N-L-F-V-D-A-V-T-K-R-I-P-Q-A-P-N-A-F-A-P-L-F-K-H-Y-R-H-I-Y-L-R-P-F-R-Y-Y-V-A-Y-R-T-T-D-E-A-I-D-I-L-A-V-R-H-G-M-E-N-P-N-A-V-E-A-E-I-S-G-R-T-F-E"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-S-S-R-Y-L-L-S-P-A-A-Q-A-H-L-E-E-I-W-D-C-T-Y-D-R-W-G-V-D-Q-A-E-Q-Y-L-R-E-L-Q-H-A-I-D-R-A-A-A-N-P-R-I-G-R-A-C-D-E-I-R-P-G-Y-R-K-L-S-A-G-S-H-T-L-F-Y-R-V-T-G-E-G-T-I-D-V-V-R-V-L-H-Q-R-M-D-V-D-R-N-L"} +{"text": "### FUNCTION Could be involved in mycobactin synthesis ### SEQUENCE -M-S-T-N-P-F-D-D-D-N-G-A-F-F-V-L-V-N-D-E-D-Q-H-S-L-W-P-V-F-A-D-I-P-A-G-W-R-V-V-H-G-E-A-S-R-A-A-C-L-D-Y-V-E-K-N-W-T-D-L-R-P-K-S-L-R-D-A-M-A-E-D"} +{"text": "### FUNCTION Could be involved in mycobactin synthesis ### SEQUENCE -M-S-T-N-P-F-D-D-D-N-G-A-F-F-V-L-V-N-D-E-D-Q-H-S-L-W-P-V-F-A-D-I-P-A-G-W-R-V-V-H-G-E-A-S-R-A-A-C-L-D-Y-V-E-K-N-W-T-D-L-R-P-K-S-L-R-D-A-M-V-E-D"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-D-I-A-G-R-S-L-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-Q-K-L-G-I-P-A-T-R-I-P-L-H-G-R-I-E-V-D-E-P-Y-V-L-I-L-P-T-Y-G-G-G-R-A-N-P-G-L-D-A-G-G-Y-V-P-K-Q-V-I-A-F-L-N-N-D-H-N-R-A-Q-L-R-G-V-I-A-A-G-N-T-N-F-G-A-E-F-C-Y-A-G-D-V-V-S-R-K-C-S-V-P-Y-L-Y-R-F-E-L-M-G-T-E-D-D-V-A-A-V-R-T-G-L-A-E-F-W-K-E-Q-T-C-H-Q-P-S-L-Q-S-L"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-A-K-L-S-G-S-I-D-V-P-L-P-P-E-E-A-W-M-H-A-S-D-L-T-R-Y-R-E-W-L-T-I-H-K-V-W-R-S-K-L-P-E-V-L-E-K-G-T-V-V-E-S-Y-V-E-V-K-G-M-P-N-R-I-K-W-T-I-V-R-Y-K-P-P-E-G-M-T-L-N-G-D-G-V-G-G-V-K-V-K-L-I-A-K-V-A-P-K-E-H-G-S-V-V-S-F-D-V-H-L-G-G-P-A-L-L-G-P-I-G-M-I-V-A-A-A-L-R-A-D-I-R-E-S-L-Q-N-F-V-T-V-F-A-G"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-G-I-L-D-K-V-K-N-L-L-S-Q-N-A-D-K-V-E-T-V-I-N-K-A-G-E-F-V-D-E-Q-T-Q-G-N-Y-S-D-A-I-H-K-L-H-D-A-A-S-N-V-V-G-M-S-D-Q-Q-S"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-T-K-E-K-I-S-V-T-V-D-A-A-V-L-A-A-I-D-A-D-A-R-A-A-G-L-N-R-S-E-M-I-E-Q-A-L-R-N-E-H-L-R-V-A-L-R-D-Y-T-A-K-T-V-P-A-L-D-I-D-A-Y-A-Q-R-V-Y-Q-A-N-R-A-A-G-S"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-S-G-H-A-L-A-A-R-T-L-L-A-A-A-D-E-L-V-G-G-P-P-V-E-A-S-A-A-A-L-A-G-D-A-A-G-A-W-R-T-A-A-V-E-L-A-R-A-L-V-R-A-V-A-E-S-H-G-V-A-A-V-L-F-A-A-T-A-A-A-A-A-A-V-D-R-G-D-P-P"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-T-H-K-R-T-K-R-Q-P-A-I-A-A-G-L-N-A-P-R-R-N-R-V-G-R-Q-H-G-W-P-A-D-V-P-S-A-E-Q-R-R-A-Q-R-Q-R-D-L-E-A-I-R-R-A-Y-A-E-M-V-A-T-S-H-E-I-D-D-D-T-A-E-L-A-L-L-S-M-H-L-D-D-E-Q-R-R-L-E-A-G-M-K-L-G-W-H-P-Y-H-F-P-D-E-P-D-S-K-Q"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-R-T-T-I-D-L-D-D-D-I-L-R-A-L-K-R-R-Q-R-E-E-R-K-T-L-G-Q-L-A-S-E-L-L-A-Q-A-L-A-A-E-P-P-P-N-V-D-I-R-W-S-T-A-D-L-R-P-R-V-D-L-D-D-K-D-A-V-W-A-I-L-D-R-G"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system Its cognate toxin is VapC48 ### SEQUENCE -M-R-T-T-I-D-L-D-D-D-I-L-R-A-L-K-R-R-Q-R-E-E-R-K-T-L-G-Q-L-A-S-E-L-L-A-Q-A-L-A-A-E-P-P-P-N-V-D-I-R-W-S-T-A-D-L-R-P-R-V-D-L-D-D-K-D-A-V-W-A-I-L-D-R-G"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-R-T-T-L-S-I-D-D-D-V-L-L-A-V-K-E-R-A-R-R-E-K-R-T-A-G-E-I-L-S-D-L-A-R-Q-A-L-T-N-Q-N-P-Q-P-A-A-S-Q-E-D-A-F-H-G-F-E-P-L-P-H-R-G-G-A-V-S-N-A-L-I-D-R-L-R-D-E-E-A-V"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system Its cognate toxin is VapC44 ### SEQUENCE -M-R-T-T-L-S-I-D-D-D-V-L-L-A-V-K-E-R-A-R-R-E-K-R-T-A-G-E-I-L-S-D-L-A-R-Q-A-L-T-N-Q-N-P-Q-P-A-A-S-Q-E-D-A-F-H-G-F-E-P-L-P-H-R-G-G-A-V-S-N-A-L-I-D-R-L-R-D-E-E-A-V"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-S-L-N-I-K-S-Q-R-T-V-A-L-V-R-E-L-A-A-R-T-G-T-N-Q-T-A-A-V-E-D-A-V-A-R-R-L-S-E-L-D-R-E-D-R-A-R-A-E-A-R-R-A-A-A-E-Q-T-L-R-D-L-D-K-L-L-S-D-D-D-K-R-L-I-R-R-H-E-V-D-L-Y-D-D-S-G-L-P-R"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system Its cognate toxin is VapC42 ### SEQUENCE -M-S-L-N-I-K-S-Q-R-T-V-A-L-V-R-E-L-A-A-R-T-G-T-N-Q-T-A-A-V-E-D-A-V-A-R-R-L-S-E-L-D-R-E-D-R-A-R-A-E-A-R-R-A-A-A-E-Q-T-L-R-D-L-D-K-L-L-S-D-D-D-K-R-L-I-R-R-H-E-V-D-L-Y-D-D-S-G-L-P-R"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-K-T-T-L-D-L-P-D-E-L-M-R-A-I-K-V-R-A-A-Q-Q-G-R-K-M-K-D-V-V-T-E-L-L-R-S-G-L-S-Q-T-H-S-G-A-P-I-P-T-P-R-R-V-Q-L-P-L-V-H-C-G-G-A-A-T-R-E-Q-E-M-T-P-E-R-V-A-A-A-L-L-D-Q-E-A-Q-W-W-S-G-H-D-D-A-A-L"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-R-T-T-L-Q-I-D-D-D-V-L-E-D-A-R-S-I-A-R-S-E-G-K-S-V-G-A-V-I-S-E-L-A-R-R-S-L-R-P-V-G-I-V-E-V-D-G-F-P-V-F-D-V-P-P-D-A-P-T-V-T-S-E-D-V-V-R-A-L-E-D-D-V"} +{"text": "### FUNCTION Probable antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-R-T-T-L-D-L-D-D-D-V-I-A-A-A-R-E-L-A-S-S-Q-R-R-S-L-G-S-V-I-S-E-L-A-R-R-G-L-M-P-G-R-V-E-A-D-D-G-L-P-V-I-R-V-P-A-G-T-P-P-I-T-P-E-M-V-R-R-A-L-D-E-D"} +{"text": "### FUNCTION Probable antitoxin component of a type II toxin-antitoxin system Its putative cognate toxin is VapC38 ### SEQUENCE -M-R-T-T-L-D-L-D-D-D-V-I-A-A-A-R-E-L-A-S-S-Q-R-R-S-L-G-S-V-I-S-E-L-A-R-R-G-L-M-P-G-R-V-E-A-D-D-G-L-P-V-I-R-V-P-A-G-T-P-P-I-T-P-E-M-V-R-R-A-L-D-E-D"} +{"text": "### FUNCTION Probable antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-R-T-T-V-T-L-D-D-D-V-E-Q-L-V-R-R-R-M-A-E-R-Q-V-S-F-K-K-A-L-N-D-A-I-R-D-G-A-S-G-R-P-A-P-S-H-F-S-T-R-T-A-D-L-G-V-P-A-V-N-L-D-R-A-L-Q-L-A-A-D-L-E-D-E-E-L-V-R-R-Q-R-R-G-S"} +{"text": "### FUNCTION Probable antitoxin component of a type II toxin-antitoxin system Its putative cognate toxin is VapC37 ### SEQUENCE -M-R-T-T-V-T-L-D-D-D-V-E-Q-L-V-R-R-R-M-A-E-R-Q-V-S-F-K-K-A-L-N-D-A-I-R-D-G-A-S-G-R-P-A-P-S-H-F-S-T-R-T-A-D-L-G-V-P-A-V-N-L-D-R-A-L-Q-L-A-A-D-L-E-D-E-E-L-V-R-R-Q-R-R-G-S"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-A-L-N-I-K-D-P-E-V-D-R-L-A-A-E-L-A-D-R-L-H-T-S-K-T-A-A-I-R-H-A-L-S-A-Q-L-A-F-L-E-S-R-A-G-D-R-E-A-Q-L-L-D-I-L-R-T-E-I-W-P-L-L-A-D-R-S-P-I-T-K-L-E-R-E-Q-I-L-G-Y-D-P-A-T-G-V"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system Its cognate toxin is VapC36 ### SEQUENCE -M-A-L-N-I-K-D-P-E-V-D-R-L-A-A-E-L-A-D-R-L-H-T-S-K-T-A-A-I-R-H-A-L-S-A-Q-L-A-F-L-E-S-R-A-G-D-R-E-A-Q-L-L-D-I-L-R-T-E-I-W-P-L-L-A-D-R-S-P-I-T-K-L-E-R-E-Q-I-L-G-Y-D-P-A-T-G-V"} +{"text": "### FUNCTION Antitoxin component of a possible type II toxin-antitoxin ### SEQUENCE -M-E-L-A-A-R-M-G-E-T-L-T-Q-A-V-V-V-A-V-R-E-Q-L-A-R-R-T-G-R-T-R-S-I-S-L-R-E-E-L-A-A-I-G-R-R-C-A-A-L-P-V-L-D-T-R-A-A-D-T-I-L-G-Y-D-E-R-G-L-P-A"} +{"text": "### FUNCTION Antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC34 ### SEQUENCE -M-E-L-A-A-R-M-G-E-T-L-T-Q-A-V-V-V-A-V-R-E-Q-L-A-R-R-T-G-R-T-R-S-I-S-L-R-E-E-L-A-A-I-G-R-R-C-A-A-L-P-V-L-D-T-R-A-A-D-T-I-L-G-Y-D-E-R-G-L-P-A"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-R-T-T-V-T-V-D-D-A-L-L-A-K-A-A-E-L-T-G-V-K-E-K-S-T-L-L-R-E-G-L-Q-T-L-V-R-V-E-S-A-R-R-L-A-A-L-G-G-T-D-P-Q-A-T-A-A-P-R-R-R-T-S-P-R"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-A-L-S-I-K-H-P-E-A-D-R-L-A-R-A-L-A-A-R-T-G-E-T-L-T-E-A-V-V-T-A-L-R-E-R-L-A-R-E-T-G-R-A-R-V-V-P-L-R-D-E-L-A-A-I-R-H-R-C-A-A-L-P-V-V-D-N-R-S-A-E-A-I-L-G-Y-D-E-R-G-L-P-A"} +{"text": "### FUNCTION Possibly the antitoxic component of a type II toxin-antitoxin ### SEQUENCE -M-R-T-T-I-D-L-P-Q-D-L-H-K-Q-A-L-A-I-A-R-D-T-H-R-T-L-S-E-T-V-A-D-L-M-R-R-G-L-A-A-N-R-P-T-A-L-S-S-D-P-R-T-G-L-P-L-V-S-V-G-T-V-V-T-S-E-D-V-R-S-L-E-D-E-Q"} +{"text": "### FUNCTION Possibly the antitoxic component of a type II toxin-antitoxin system Its cognate toxin is VapC29 ### SEQUENCE -M-R-T-T-I-D-L-P-Q-D-L-H-K-Q-A-L-A-I-A-R-D-T-H-R-T-L-S-E-T-V-A-D-L-M-R-R-G-L-A-A-N-R-P-T-A-L-S-S-D-P-R-T-G-L-P-L-V-S-V-G-T-V-V-T-S-E-D-V-R-S-L-E-D-E-Q"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-A-L-N-I-K-D-P-S-V-H-Q-A-V-K-Q-I-A-K-I-T-G-E-S-Q-A-R-A-V-A-T-A-V-N-E-R-L-A-R-L-R-S-D-D-L-A-A-R-L-L-A-I-G-H-K-T-A-S-R-M-S-P-E-A-K-R-L-D-H-D-A-L-L-Y-D-E-R-G-L-P-A"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-I-R-T-Q-V-Q-L-P-D-E-L-Y-R-D-A-K-R-V-A-H-E-H-E-M-T-L-A-E-V-V-R-R-G-L-E-H-M-V-R-I-Y-P-R-R-D-A-A-S-D-T-W-Q-P-P-T-P-R-R-L-G-P-F-R-A-S-E-E-T-W-R-E-L-A-N-E-A"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system Its cognate toxin is VapC24 ### SEQUENCE -M-I-R-T-Q-V-Q-L-P-D-E-L-Y-R-D-A-K-R-V-A-H-E-H-E-M-T-L-A-E-V-V-R-R-G-L-E-H-M-V-R-I-Y-P-R-R-D-A-A-S-D-T-W-Q-P-P-T-P-R-R-L-G-P-F-R-A-S-E-E-T-W-R-E-L-A-N-E-A"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-H-R-G-Y-A-L-V-V-C-S-P-G-V-T-R-T-M-I-D-I-D-D-D-L-L-A-R-A-A-K-E-L-G-T-T-T-K-K-D-T-V-H-A-A-L-R-A-A-L-R-A-S-A-A-R-S-L-M-N-R-M-A-E-N-A-T-G-T-Q-D-E-A-L-V-N-A-M-W-R-D-G-H-P-E-N-T-A"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Neutralizes the toxic effect of cognate toxin VapC20 ### SEQUENCE -M-L-V-A-Y-I-C-H-V-K-R-L-Q-I-Y-I-D-E-D-V-D-R-A-L-A-V-E-A-R-R-R-R-T-S-K-A-A-L-I-R-E-Y-V-A-E-H-L-R-Q-P-G-P-D-P-V-D-A-F-V-G-S-F-V-G-E-A-D-L-S-A-S-V-D-D-V-V-Y-G-K-H-E"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin ### SEQUENCE -M-S-T-T-I-V-A-G-V-I-Q-G-H-L-P-V-I-L-P-T-R-R-R-A-R-D-L-G-H-T-T-A-L-F-R-A-Q-T-L-Q-C-I-Y-L-S-I-E-Y-L-Y-V-C-S-M-S-R-R-T-T-I-D-I-D-D-I-L-L-A-R-A-Q-A-A-L-G-T-T-G-L-K-D-R-V-D-A-A-L-R-A-A-V-R"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC18 ### SEQUENCE -M-S-T-T-I-V-A-G-V-I-Q-G-H-L-P-V-I-L-P-T-R-R-R-A-R-D-L-G-H-T-T-A-L-F-R-A-Q-T-L-Q-C-I-Y-L-S-I-E-Y-L-Y-V-C-S-M-S-R-R-T-T-I-D-I-D-D-I-L-L-A-R-A-Q-A-A-L-G-T-T-G-L-K-D-R-V-D-A-A-L-R-A-A-V-R"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin ### SEQUENCE -M-T-V-K-R-T-T-I-E-L-D-E-D-L-V-R-A-A-Q-A-V-T-G-E-T-L-R-A-T-V-E-R-A-L-Q-Q-L-V-A-A-A-A-E-Q-A-A-A-R-R-R-R-I-V-D-H-L-A-H-A-G-T-H-V-D-A-D-V-L-L-S-E-Q-A-W-R"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC17 ### SEQUENCE -M-T-V-K-R-T-T-I-E-L-D-E-D-L-V-R-A-A-Q-A-V-T-G-E-T-L-R-A-T-V-E-R-A-L-Q-Q-L-V-A-A-A-A-E-Q-A-A-A-R-R-R-R-I-V-D-H-L-A-H-A-G-T-H-V-D-A-D-V-L-L-S-E-Q-A-W-R"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin ### SEQUENCE -M-S-K-R-L-Q-V-L-L-D-P-D-E-W-E-E-L-R-E-I-A-R-R-H-R-T-T-V-S-E-W-V-R-R-T-L-R-E-A-R-E-R-E-P-R-G-D-L-D-M-K-L-R-S-V-R-A-A-A-R-H-E-F-P-T-A-D-V-E-Q-M-L-E-E-I-E-R-G-R-G-A-E-R-E-G-S-R"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC13 ### SEQUENCE -M-S-K-R-L-Q-V-L-L-D-P-D-E-W-E-E-L-R-E-I-A-R-R-H-R-T-T-V-S-E-W-V-R-R-T-L-R-E-A-R-E-R-E-P-R-G-D-L-D-M-K-L-R-S-V-R-A-A-A-R-H-E-F-P-T-A-D-V-E-Q-M-L-E-E-I-E-R-G-R-G-A-E-R-E-G-S-R"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin ### SEQUENCE -M-S-A-M-V-Q-I-R-N-V-P-D-E-L-L-H-E-L-K-A-R-A-A-A-Q-R-M-S-L-S-D-F-L-L-A-R-L-A-E-I-A-E-E-P-A-L-D-D-V-L-D-R-L-A-A-L-P-R-R-D-L-G-A-S-A-A-E-L-V-D-E-A-R-S-E"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC12 ### SEQUENCE -M-S-A-M-V-Q-I-R-N-V-P-D-E-L-L-H-E-L-K-A-R-A-A-A-Q-R-M-S-L-S-D-F-L-L-A-R-L-A-E-I-A-E-E-P-A-L-D-D-V-L-D-R-L-A-A-L-P-R-R-D-L-G-A-S-A-A-E-L-V-D-E-A-R-S-E"} +{"text": "### FUNCTION Antitoxin component of a possible type II toxin-antitoxin ### SEQUENCE -M-K-T-L-Y-L-R-N-V-P-D-D-V-V-E-R-L-E-R-L-A-E-L-A-K-T-S-V-S-A-V-A-V-R-E-L-T-E-A-S-R-R-A-D-N-P-A-L-L-G-D-L-P-D-I-G-I-D-T-T-E-L-I-G-G-I-D-A-E-R-A-G-R"} +{"text": "### FUNCTION Antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC9 ### SEQUENCE -M-K-T-L-Y-L-R-N-V-P-D-D-V-V-E-R-L-E-R-L-A-E-L-A-K-T-S-V-S-A-V-A-V-R-E-L-T-E-A-S-R-R-A-D-N-P-A-L-L-G-D-L-P-D-I-G-I-D-T-T-E-L-I-G-G-I-D-A-E-R-A-G-R"} +{"text": "### FUNCTION Antitoxin component of a possible type II toxin-antitoxin ### SEQUENCE -M-S-V-T-Q-I-D-L-D-D-E-A-L-A-D-V-M-R-I-A-A-V-H-T-K-K-E-A-V-N-L-A-M-R-D-Y-V-E-R-F-R-R-I-E-A-L-A-R-S-R-E"} +{"text": "### FUNCTION Antitoxin component of a possible type II toxin-antitoxin system The cognate toxin is VapC6 ### SEQUENCE -M-S-V-T-Q-I-D-L-D-D-E-A-L-A-D-V-M-R-I-A-A-V-H-T-K-K-E-A-V-N-L-A-M-R-D-Y-V-E-R-F-R-R-I-E-A-L-A-R-S-R-E"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-L-S-R-R-T-K-T-I-V-V-C-T-L-V-C-M-A-R-L-N-V-Y-V-P-D-E-L-A-E-R-A-R-A-R-G-L-N-V-S-A-L-T-Q-A-A-I-S-A-E-L-E-N-S-A-T-D-A-W-L-E-G-L-E-P-R-S-T-G-A-R-H-D-D-V-L-G-A-I-D-A-A-R-D-E-F-E-A"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-V-V-N-R-A-L-L-A-S-V-D-A-L-S-R-D-E-Q-I-E-L-V-E-H-I-N-G-N-L-A-E-G-M-H-I-S-E-A-N-Q-A-L-I-E-A-R-A-N-D-T-D-D-A-H-W-S-T-I-D-D-F-D-K-R-I-R-A-R-L-G"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to cognate MazF6 toxin and counteracts its endoribonuclease activity ### SEQUENCE -M-K-T-A-I-S-L-P-D-E-T-F-D-R-V-S-R-R-A-S-E-L-G-M-S-R-S-E-F-F-T-K-A-A-Q-R-Y-L-H-E-L-D-A-Q-L-L-T-G-Q-I-D-R-A-L-E-S-I-H-G-T-D-E-A-E-A-L-A-V-A-N-A-Y-R-V-L-E-T-M-D-D-E-W"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to its cognate MazF5 endoribonuclease toxin and neutralizes its activity ### SEQUENCE -M-K-T-A-R-L-Q-V-T-L-R-C-A-V-D-L-I-N-S-S-S-D-Q-C-F-A-R-I-E-H-V-A-S-D-Q-A-D-P-R-P-G-V-W-H-S-S-G-M-N-R-I-R-L-S-T-T-V-D-A-A-L-L-T-S-A-R-D-M-R-A-G-I-T-D-A-A-L-I-D-E-A-L-A-A-L-L-A-R-H-R-S-A-E-V-D-A-S-Y-A-A-Y-D-K-H-P-V-D-E-P-D-E-W-G-D-L-A-S-W-R-R-A-A-G-D-S"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to cognate MazF4 toxin and counteracts its endoribonuclease activity ### SEQUENCE -M-P-F-L-V-A-L-S-G-I-I-S-G-V-H-D-H-S-M-T-V-R-L-D-Q-Q-T-R-Q-R-L-Q-D-I-V-K-G-G-Y-R-S-A-N-A-A-I-V-D-A-I-N-K-R-W-E-A-L-H-D-E-Q-L-D-A-A-Y-A-A-A-I-H-D-N-P-A-Y-P-Y-E-S-E-A-E-R-S-A-A-R-A-R-R-N-A-R-Q-Q-R-S-A-Q"} +{"text": "### FUNCTION Required for ESX-1 function Required for the maintenance of adequate cellular levels of both EspA and EspC Facilitates EsxA secretion ### SEQUENCE -M-D-L-P-G-N-D-F-D-S-N-D-F-D-A-V-D-L-W-G-A-D-G-A-E-G-W-T-A-D-P-I-I-G-V-G-S-A-A-T-P-D-T-G-P-D-L-D-N-A-H-G-Q-A-E-T-D-T-E-Q-E-I-A-L-F-T-V-T-N-P-P-R-T-V-S-V-S-T-L-M-D-G-R-I-D-H-V-E-L-S-A-R-V-A-W-M-S-E-S-Q-L-A-S-E-I-L-V-I-A-D-L-A-R-Q-K-A-Q-S-A-Q-Y-A-F-I-L-D-R-M-S-Q-Q-V-D-A-D-E-H-R-V-A-L-L-R-K-T-V-G-E-T-W-G-L-P-S-P-E-E-A-A-A-A-E-A-E-V-F-A-T-R-Y-S-D-D-C-P-A-P-D-D-E-S-D-P-W"} +{"text": "### FUNCTION Controls rRNA transcription by binding to the RNA polymerase ### SEQUENCE -M-I-F-K-V-G-D-T-V-V-Y-P-H-H-G-A-A-L-V-E-A-I-E-T-R-T-I-K-G-E-Q-K-E-Y-L-V-L-K-V-A-Q-G-D-L-T-V-R-V-P-A-E-N-A-E-Y-V-G-V-R-D-V-V-G-Q-E-G-L-D-K-V-F-Q-V-L-R-A-P-H-T-E-E-P-T-N-W-S-R-R-Y-K-A-N-L-E-K-L-A-S-G-D-V-N-K-V-A-E-V-V-R-D-L-W-R-R-D-Q-E-R-G-L-S-A-G-E-K-R-M-L-A-K-A-R-Q-I-L-V-G-E-L-A-L-A-E-S-T-D-D-A-K-A-E-T-I-L-D-E-V-L-A-A-A-S"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-R-T-T-I-R-I-D-D-E-L-Y-R-E-V-K-A-K-A-A-R-S-G-R-T-V-A-A-V-L-E-D-A-V-R-R-G-L-N-P-P-K-P-Q-A-A-G-R-Y-R-V-Q-P-S-G-K-G-G-L-R-P-G-V-D-L-S-S-N-A-A-L-A-E-A-M-N-D-G-V-S-V-D-A-V-R"} +{"text": "### FUNCTION May play a regulatory role in sulfomenaquinone biosynthesis ### SEQUENCE -M-A-N-D-A-R-P-L-A-R-L-A-N-C-R-V-G-D-Q-S-S-A-T-H-A-Y-T-V-G-P-V-L-G-V-P-P-T-G-G-V-D-L-R-Y-G-G-R-A-G-I-G-R-S-E-T-V-T-D-H-G-A-V-G-R-R-Y-H-Q-P-C-A-G-Q-I-R-L-S-E-L-R-V-T-I-L-L-R-C-E-T-L-C-E-T-A-Q-L-L-R-C-P-P-L-P-C-D-C-S-T-P-L"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-Y-R-W-C-M-S-R-T-N-I-D-I-D-D-E-L-A-A-E-V-M-R-R-F-G-L-T-T-K-R-A-A-V-D-L-A-L-R-R-L-V-G-S-P-L-S-R-E-F-L-L-G-L-E-G-V-G-W-E-G-D-L-D-D-L-R-S-D-R-P-D"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin ### SEQUENCE -M-K-R-T-N-I-Y-L-D-E-E-Q-T-A-S-L-D-K-L-A-A-Q-E-G-V-S-R-A-E-L-I-R-L-L-L-N-R-A-L-T-T-A-G-D-D-L-A-S-D-L-Q-A-I-N-D-S-F-G-T-L-R-H-L-D-P-P-V-R-R-S-G-G-R-E-Q-H-L-A-Q-V-W-R-A-T-S"} +{"text": "### FUNCTION The initiation process of transfer DNA synthesis requires the interaction of at least three plasmid-specific components at the transfer origin resulting in the assembly of a specialized nucleoprotein complex - the relaxosome ### SEQUENCE -M-S-E-P-K-D-Q-S-I-E-D-E-L-D-A-A-L-A-A-L-D-S-G-P-L-P-T-S-T-L-P-E-P-Q-P-S-P-E-Q-A-T-A-G-Q-P-P-A-E-A-T-A-P-T-P-A-F-T-P-P-P-S-T-G-S-P-T-L-D-A-L-E-E-N-R-R-P-K-A-S-T-V-C-E-H-C-P-N-S-V-W-F-A-S-P-A-E-V-K-C-Y-C-R-V-M-F-L-V-T-W-S-S-K-E-P-N-Q-I-T-H-C-D-G-E-F-L-G-Q-E-Q-E"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-T-P-G-T-A-V-L-E-E-L-K-R-L-S-S-A-E-E-I-F-D-A-L-D-H-P-Y-R-P-E-V-V-Q-V-A-R-L-H-I-M-K-R-L-G-Q-Y-L-A-A-V-D-F-A-T-L-D-P-A-D-A-R-A-A-A-R-D-A-L-S-R-A-Y-T-D-F-V-D-S-S-P-L-E-Q-K-V-F-K-V-F-A-K-P-S-R-A-F-V-P-L-S-G-L-S-V-V-E-D"} +{"text": "### FUNCTION Plays a role in the expression of some T4 genes involved in DNA synthesis including the helicase/primase gp41 May act as a transcriptional antitermination factor ### SEQUENCE -M-A-I-K-F-E-V-N-K-W-Y-Q-F-K-N-K-Q-A-Q-E-N-F-I-K-D-H-T-D-N-G-I-Y-A-R-R-L-G-M-E-P-F-K-I-L-D-A-D-Y-L-G-R-P-T-K-I-M-T-S-I-G-V-L-K-R-C-A-G-G-D-I-L-D-E-N-F-I-W-L-S-T-N-E-A-G-F-F-D-E-V-E-N-P-Y-Q-A-V-E-E-Q-E-Q-E-E-K-E-Q-E-Q-I-E-D-F-T-E-F-P-V-M-K-V-T-I-E-N-N-D-Q-A-W-S-L-Y-Q-M-L-K-A-Y-F-K-E"} +{"text": "### FUNCTION May have a regulatory function ### SEQUENCE -M-Q-A-Q-T-F-S-H-L-H-S-Q-S-S-Q-R-T-T-E-V-T-L-Y-L-T-I-P-E-S-Y-R-Q-E-P-I-V-T-Q-L-V-S-R-Y-Q-L-Q-V-N-I-L-A-A-T-L-G-T-N-G-G-Q-G-Q-F-K-L-T-L-I-G-H-A-Q-A-I-N-N-A-L-A-Y-L-E-Q-L-Q-V-T-I-V-L-D-Q-E-S-D-G-W"} +{"text": "### FUNCTION Involved in the biosynthesis of bilin ### SEQUENCE -M-D-A-C-V-S-M-S-E-N-Y-F-D-E-A-L-P-R-L-L-A-L-L-N-D-P-D-P-T-I-Y-R-T-A-V-K-G-L-G-V-F-G-H-G-V-L-F-P-L-L-D-L-Y-D-K-T-D-N-G-T-V-K-A-C-C-I-K-A-F-V-Q-V-A-V-N-F-P-D-A-V-F-P-E-Q-A-I-Q-A-L-K-L-A-L-D-D-I-N-P-V-V-S-Q-S-A-L-M-T-L-G-Y-F-S-K-Q-E-H-E-K-E-R-V-I-P-I-L-I-Q-V-C-N-S-T-N-I-A-H-V-Q-S-A-V-M-S-L-A-E-I-D-S-T-E-V-D-Q-C-F-E-R-M-I-N-H-D-S-T-D-V-L-I-K-E-I-L-E-A-S-M-S-R-R-Q-S-L-F-G-N"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-M-C-R-K-Y-H-E-E-L-P-G-L-D-R-P-P-Y-P-G-A-K-G-E-D-I-Y-N-N-V-S-R-K-A-W-D-E-W-Q-K-H-Q-T-M-L-I-N-E-R-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-Q-E-M-D-K-F-L-S-G-E-D-Y-A-K-A-D-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-F-L-L-I-G-L-I-R-F-Y-Q-Y-A-I-S-P-L-I-G-P-R-C-R-F-Y-P-S-C-S-H-Y-T-L-E-A-I-R-V-H-G-A-L-R-G-G-Y-L-G-A-R-R-L-L-R-C-H-P-W-H-P-G-G-Y-D-P-V-P-E-R-Q-E-Q-A-C-A-C-H-R-T-A-K-P-G-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-V-L-V-K-A-V-H-G-Y-Q-R-W-I-S-P-V-F-P-P-A-C-R-Y-Y-P-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-P-A-K-G-L-A-M-G-T-A-R-I-L-R-C-H-P-F-C-Q-P-G-Y-D-L-V-P-K-H-F-S-L-R-R-N-W-A-E-P-E-K-K-E-E-E-D-S-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-T-L-F-E-F-Y-A-T-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-N-I-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-V-L-E-S-Y-E-E-K-L-H-L-F-S-N-Y-V-V-R-N-Q-L-L-E-E-L-M-K-K-Y-P-S-D-Q-Y-L-I-S-K-L-Q-E-I-Q-Q-I-D-E-E-E-F"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-L-A-Y-F-S-V-T-G-Q-T-R-R-F-V-S-K-T-D-L-P-N-V-E-I-T-P-D-D-D-L-E-M-D-E-P-F-L-L-I-T-P-S-Y-A-E-E-S-P-T-V-S-K-S-I-D-V-M-D-P-V-F-D-F-M-A-Y-N-D-N-Y-K-H-C-R-G-I-I-G-T-G-N-R-N-F-A-G-I-Y-I-F-T-A-K-E-V-S-A-K-Y-Q-I-P-L-L-Y-D-F-E-F-N-G-T-P-A-D-V-A-A-V-E-K-L-A-A-Q-L-D-Q-G-A-K-V-T-F-K-N-P-L"} +{"text": "### FUNCTION Activates int gene expression, probably by direct DNA-binding Int activation requires both rinA and rinB ### SEQUENCE -M-T-K-K-K-Y-G-L-K-L-S-T-V-R-K-L-E-D-E-L-C-D-Y-P-N-Y-H-K-Q-L-E-D-L-R-S-E-I-M-T-P-W-I-P-T-D-T-N-I-G-G-E-F-V-P-S-N-T-S-K-T-E-M-A-V-T-N-Y-L-C-S-I-R-R-G-K-I-L-E-F-K-S-A-I-E-R-I-I-N-S-S-S-R-K-E-R-E-F-I-Q-E-Y-Y-F-N-K-K-E-L-V-K-V-C-V-D-I-H-I-S-D-R-T-A-H-R-I-K-R-K-I-I-S-R-L-A-E-E-L-G-E-D"} +{"text": "### FUNCTION Activates int gene expression, probably by providing stability to rinA Int activation requires both rinA and rinB ### SEQUENCE -M-G-C-L-V-V-V-K-E-I-L-R-L-L-F-L-L-A-M-Y-E-L-G-K-Y-V-T-E-Q-V-Y-I-M-M-T-A-N-D-D-V-E-A-P-S-D-F-A-K-L-S-D-Q-S-D-L-M-R-A-E-V-S-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-A-D-K-Y-D-V-F-D-Q-L-G-E-L-E-N-T-L-N-T-T-L-T-Q-I-S-G-I-R-Q-V-L-E-A-S-M-T-E-N-A-T-L-R-M-E-L-E-K-L-R-D-R-L-A-E-F-E-K-K-E-V-K-K-E-T-P-K-D-Q-P-N-P-N-L-I-Q-I-F-N-E-G-F-H-V-C-H-L-H-Y-A-E-R-L-A-E-G-E-S-C-L-D-C-L-E-L-L-Y-R"} +{"text": "### FUNCTION Required for optimal exotoxin A production ### SEQUENCE -M-R-L-P-A-V-T-P-G-W-P-A-I-P-P-G-A-T-L-G-G-F-D-G-Q-G-R-R-S-W-A-T-I-S-R-A-P-S-G-A-S-C-S-R-N-R-S-A-T-R-T-Y-G-W-G-A-T-A-T-T-P-A-T-I-T-G-I-P-S-T-T-A-P-A-T"} +{"text": "### FUNCTION Protects virus-infected cells from TNF-induced cytolysis ### SEQUENCE -M-E-P-D-G-V-H-A-E-Q-Q-F-I-L-N-Q-I-S-C-A-N-T-A-L-Q-R-Q-R-E-E-L-A-S-L-V-M-L-H-A-C-K-R-G-L-F-C-P-V-K-T-Y-K-L-S-L-N-A-S-A-S-E-H-S-L-H-F-E-K-S-P-S-R-F-T-L-V-N-T-H-A-G-A-S-V-R-V-A-L-H-H-Q-G-A-S-G-S-I-R-C-S-C-S-H-A-E-C-L-P-V-L-L-K-T-L-C-A-F-N-F-L-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-E-K-K-E-L-Y-D-G-F-L-T-L-E-K-H-A-Q-Q-M-L-R-E-I-A-A-M-K-D-D-M-A-E-T-L-E-R-N-A-E-L-E-I-E-N-K-H-L-R-Q-H-L-A-E-L-E-K-D-D-N-K-T-S-D-G-G-V-E-L-S-K-S-K-Q-N-L-E-S-L-Y-N-E-G-F-H-V-C-P-M-F-Y-G-Q-R-R-V-N-D-E-P-C-A-F-C-T-E-I-I-Y-G-E-N"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-N-Y-R-M-N-S-L-F-E-F-Y-G-P-L-L-T-D-K-Q-H-A-Y-L-A-L-Y-Y-G-D-D-Y-S-L-G-E-I-A-T-E-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-E-A-S-L-E-E-Y-E-K-K-L-H-L-F-A-N-Y-Q-A-Q-N-E-A-V-D-T-L-V-S-Y-A-R-T-H-Y-P-D-D-K-A-L-S-T-L-L-E-R-V-A-D-Q-T-A-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-V-L-T-W-L-V-R-G-Y-Q-R-F-I-S-P-L-L-P-P-S-C-R-Y-Y-P-T-C-S-T-Y-M-I-Q-A-L-Q-K-H-G-A-I-K-G-S-L-M-G-I-A-R-I-L-R-C-N-P-F-V-K-G-G-L-D-P-V-P-A-F-F-T-L-R-R-N-P-H-P-E-N-D-L-D-L-S-D-I-Q-N-L-N-H-K-L-G-G-R-H-G"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-D-L-F-D-Q-I-T-E-V-T-R-N-T-E-D-L-L-N-K-L-H-E-T-Q-S-A-M-V-E-I-M-E-E-N-A-E-L-Q-I-E-N-Q-H-L-R-E-R-L-K-Q-A-T-A-A-E-N-E-G-T-K-N-T-K-Y-G-L-S-K-S-L-Q-N-L-E-K-L-Y-A-S-G-Y-H-V-C-N-E-F-Y-G-K-H-R-Q-D-E-E-E-C-A-F-C-L-T-V-I-Y-G-D-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-L-L-L-I-I-R-G-Y-Q-K-F-I-S-P-M-F-P-P-S-C-R-Y-Y-P-T-C-S-N-Y-S-L-Q-A-I-K-R-F-G-A-I-K-G-G-L-M-G-V-A-R-I-L-R-C-H-P-F-V-R-G-G-Y-D-P-V-P-D-N-F-S-L-K-R-N-Q-K-N-S-K-P-R-N"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-N-N-R-I-N-S-L-L-E-F-Y-E-Q-L-L-T-P-K-Q-K-E-Y-I-T-L-Y-Y-A-D-D-Y-S-L-G-E-I-S-E-E-F-Q-V-S-R-Q-A-V-Y-D-N-I-K-R-T-V-N-I-L-E-K-Y-E-Q-Q-L-H-L-L-S-N-F-E-V-R-N-A-K-F-D-Q-I-R-A-Y-I-N-Q-K-Y-P-E-D-T-E-L-K-H-F-L-D-D-L-E-K-S-E-E-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-D-I-M-E-K-Y-A-D-D-S-Y-L-Q-E-Q-I-A-I-L-S-S-I-D-N-R-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-F-L-I-A-L-V-K-A-Y-Q-R-W-I-S-P-L-F-P-L-S-C-R-F-C-P-T-C-S-V-Y-M-I-Q-A-I-E-K-H-G-L-K-G-V-L-M-G-I-A-R-I-L-R-C-H-P-L-S-E-T-G-D-D-P-V-P-D-Y-F-S-L-K-R-K-K-T-P-L-D-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-H-I-L-I-W-F-V-R-G-Y-Q-R-F-I-S-P-L-F-P-P-T-C-R-Y-Y-P-T-C-S-T-Y-M-V-Q-A-L-S-K-H-G-A-L-K-G-S-L-M-G-L-A-R-I-L-R-C-Q-P-F-V-R-G-G-I-D-P-V-P-D-H-F-T-L-K-R-N-T-A-A-E-A-A-Y-R-Q-A-M-Q-L-D-E-I-E-R-H-P-H-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-N-Y-R-I-N-S-L-F-A-F-Y-Q-P-L-L-T-A-K-Q-N-N-Y-M-Q-L-Y-Y-G-D-D-Y-S-L-G-E-I-A-E-E-F-N-V-S-R-Q-A-V-Y-D-N-L-R-R-T-E-K-I-L-E-D-Y-E-E-K-L-H-L-Y-Q-E-F-T-A-R-N-R-Q-A-D-E-I-Q-A-Y-V-A-T-T-Y-P-H-D-S-R-L-N-R-L-V-A-G-L-E-N-L-E-E-Q"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-K-L-L-I-G-L-V-N-V-Y-K-K-F-I-S-P-V-L-P-P-T-C-R-Y-Y-P-T-C-S-T-Y-M-I-D-A-L-K-K-H-G-A-I-L-G-L-I-M-G-I-S-R-I-I-R-C-N-P-F-I-K-G-G-V-D-P-V-P-D-Y-F-T-L-R-R-N-P-H-P-E-R-Y-E-D-E-I-I-A-Q-A-F-H-S-N-K-K"} +{"text": "### FUNCTION May be involved in growth at elevated pH and presence of calcium ### SEQUENCE -M-K-T-F-F-L-I-E-A-G-R-A-L-Q-I-V-A-F-R-P-A-I-T-T-V-L-F-Q-R-F-S-V-S-F-S-C-S-Y-F-T-C-C-T-S-Q-L-L-R-E-N-W-L-F-K-F-L-T-A-F-D-H-V-I-R-A-S-N-D-L-S-T-M-R-F-M-I-M-Y-I-Y-V-Y-I-Y-I-Y-T-V-L-R-K-R-L-S-C-Y-M-L-I-L"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-P-F-S-Q-L-S-Q-L-Q-Q-N-L-Q-A-M-T-K-T-V-A-G-L-E-N-D-M-L-E-V-L-K-E-N-T-E-L-K-V-E-N-Q-L-L-R-E-K-I-S-K-L-D-A-N-K-E-P-A-E-N-K-S-Q-A-G-L-K-S-L-R-N-I-Y-D-S-G-Y-H-I-C-N-M-Y-Y-G-S-H-R-E-S-G-E-D-C-M-F-C-L-D-I-L-D-N-F-V-N-H-G-Q-K-N-R-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-L-V-R-F-Y-Q-R-F-I-S-P-V-F-P-P-S-C-R-F-E-L-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-F-K-G-V-L-M-G-L-A-R-I-L-R-C-H-P-W-S-K-T-G-K-D-P-V-P-D-H-F-S-L-K-R-N-Q-E-G-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-Q-I-L-E-R-Y-P-K-D-N-F-L-Q-E-Q-I-E-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Involved in late/very late gene activation ### SEQUENCE -M-P-W-R-A-Q-D-H-S-V-D-C-L-T-R-S-E-V-Y-A-L-W-A-E-A-V-N-T-L-K-R-N-L-Q-V-K-N-V-S-A-H-L-L-E-D-D-A-A-D-V-K-D-Y-I-R-A-N-L-S-R-F-T-V-I-T-G-K-C-S-R-R-T-V-C-H-H-H-R-R-V-Q-R-T-L-E-P-R-Q-D-L-V-N-E-Y-A-C-S-V-T-D-V-Y-R-S-P-K-W-S-I-C-P-T-T-C-T-R-S-R-S-P-T-T-T-P-R"} +{"text": "### FUNCTION Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces halstedii ### SEQUENCE -M-A-G-H-T-E-N-E-I-V-I-A-A-P-L-D-L-V-W-D-M-T-N-D-V-E-N-W-P-R-L-F-S-E-Y-A-S-A-E-I-L-E-R-E-G-D-R-V-R-F-R-L-T-M-H-P-D-D-E-G-R-V-W-S-W-V-S-E-R-V-A-D-R-A-S-L-T-V-R-A-H-R-V-E-T-G-P-F-Q-F-M-D-I-Q-W-V-Y-E-Q-T-P-E-G-V-L-M-R-W-I"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-T-P-E-S-P-T-L-A-A-L-T-K-L-S-S-A-E-E-I-F-A-F-L-G-V-E-P-I-R-E-V-L-N-S-S-R-L-H-I-M-K-R-F-G-A-Y-L-R-E-T-D-M-T-G-L-T-E-D-G-I-F-E-R-A-R-D-A-L-L-R-A-Q-A-D-F-V-A-S-T-P-L-K-E-K-V-F-K-V-F-E-T-E-A-A-K-R-K-A-R-F-V-G-L-E-T-L-K-V-I-K-S"} +{"text": "### FUNCTION Probably facilitates nickel incorporation May constitute a multicomponent high-affinity nickel transporter Not essential for the expression of catalytically active urease ### SEQUENCE -M-G-T-R-K-F-F-L-L-H-H-D-K-I-I-R-S-I-I-M-A-N-G-I-K-N-Y-W-Q-D-D-G-R-F-D-R-C-S-E-I-F-F-L-S-Q-K-Q-G-R-G-L-Y-R-F-W-L-G-N-K-K-Q-G-N-R-D"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-S-F-K-D-D-L-E-D-L-E-T-A-E-D-F-L-R-F-L-G-V-T-Y-E-Q-R-V-V-N-V-N-R-L-H-I-L-Q-R-F-Q-D-Y-L-S-A-D-T-G-M-E-G-L-D-D-E-G-M-A-A-R-Y-S-A-H-L-E-R-A-Y-Q-D-F-V-A-S-N-A-I-A-E-K-T-F-K-V-H-Q-E-E-A-R-K-M-A-D-R-F-V-P-L-D-A-L-L-P-T"} +{"text": "### FUNCTION Chaperone for the type III secretion of Tir Probably stabilizes the protein, prevents inappropriate protein-proteininteractions and aids in secretion ### SEQUENCE -M-S-S-R-S-E-L-L-L-E-R-F-A-E-K-I-G-I-G-T-I-S-F-N-E-N-R-L-C-S-F-V-I-D-E-I-Y-Y-I-S-L-S-D-T-N-D-E-Y-M-M-I-Y-G-V-C-G-K-F-P-T-D-N-P-N-F-A-L-E-I-L-N-A-N-L-W-F-R-E-N-G-G-P-Y-L-C-Y-E-S-G-A-Q-S-L-L-L-A-L-R-F-P-L-D-D-V-T-P-E-K-L-E-N-E-I-E-V-V-V-K-S-M-E-N-L-Y-L-V-L-H-N-Q-G-I-T-L-E-N-E-H-M-K-I-E-E-I-S-S-N-D-N-K-H-Y-Y-A-G-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-S-N-L-C-P-D-C-A-R-A-A-L-R-L-P-R-Q-A-G-R-G-A-I-W-L-Y-R-H-T-L-S-P-L-V-G-Y-H-C-R-H-L-P-T-C-S-V-Y-G-D-E-A-I-G-R-F-G-L-W-A-G-G-W-M-T-L-A-R-L-L-R-C-Q-P-W-G-T-S-G-I-D-N-V-P-A-E-P-P-G-G-A-R-W-Y-L-P-W-R-Y-G-R-W-R-G-V-N-D"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-T-A-A-F-D-R-Y-V-S-F-K-N-A-D-W-E-G-K-S-Q-R-V-M-E-R-L-Q-I-H-I-D-A-A-Q-N-P-F-W-A-Y-F-A-Q-K-R-T-E-L-N-Q-K-Q-G-L-D-D-L-R-V-L-H-N-Y-L-P-T-L-R-E-I-L-E-D-N-G-D-Q-E-T-L-A-M-L-E-D-L-E-V-T-C-M"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-L-Q-W-L-A-T-T-V-I-R-G-Y-Q-I-L-I-S-P-L-L-G-P-R-C-R-F-N-P-T-C-S-Y-Y-A-I-E-A-I-K-T-H-G-T-V-K-G-S-W-F-A-M-K-R-I-L-K-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-H-C-Q-H-L-N-K-S-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-G-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-T-N-F-L-F-E-G-K-D-V-E-I-E-G-Y-V-P-P-A-E-D-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-M-V-Q-C-V-R-L-G-R-E-A-E-G-L-P-R-P-P-Y-P-G-E-L-G-K-R-I-Y-E-N-V-S-K-E-A-W-Q-E-W-L-R-H-Q-T-M-L-I-N-E-Y-R-L-T-P-V-E-P-R-A-R-Q-F-L-E-K-E-M-E-N-F-F-F-G-D-G-S-S-A-P-P-D-Y-Q-P-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-L-I-I-G-L-I-K-L-Y-Q-Y-S-I-G-L-L-I-P-P-S-C-R-F-Y-P-T-C-S-N-Y-M-R-E-A-L-T-K-H-G-L-I-K-G-L-W-L-G-T-R-R-I-L-R-C-H-P-W-N-P-G-G-Y-D-P-I-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-N-V-Q-C-I-K-L-G-C-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-K-R-I-F-E-N-V-S-R-E-A-W-G-Q-W-I-K-H-Q-T-M-L-V-N-E-M-R-L-S-M-A-D-I-K-A-R-K-Y-L-A-T-Q-M-E-A-Y-F-F-G-E-G-A-E-Q-P-V-G-Y-V-P-P-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-E-M-L-I-K-L-I-K-I-Y-Q-K-A-T-F-F-K-P-A-S-C-R-F-Y-P-S-C-S-N-Y-S-I-E-A-L-R-K-Y-G-I-V-K-G-G-W-L-T-V-K-R-L-A-R-C-H-P-Y-N-P-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-E-T-V-L-I-A-L-L-R-F-Y-K-V-A-V-S-P-M-L-G-N-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-V-R-R-V-C-R-C-H-P-F-S-A-G-G-I-D-L-V-P-P-P-N-S-D-T-R-A-R-G-E-A-D-A-R-S-H-R-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-Q-C-A-K-L-G-K-E-A-E-A-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-S-V-S-K-E-A-W-Q-G-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-D-G-A-D-Q-A-S-G-F-V-P-P-T-E-G"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-I-S-W-I-R-T-L-G-A-L-L-L-L-A-S-V-A-Q-A-Q-F-Q-F-F-E-H-M-F-G-N-G-G-H-Q-Q-Q-R-S-Q-N-V-P-S-D-S-A-R-Y-Q-S-M-W-D-S-A-Q-C-D-K-Y-L-C-P-G-T-L-A-C-V-H-F-P-H-H-C-P-C-P-H-P-D-V-E-E-K-V-E-L-G-E-G-S-A-V-C-V-S-R-G-G-Y-R-Q-G-E-A-S-R-K-I-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-L-Q-W-L-A-T-T-F-I-R-G-Y-Q-I-F-I-S-P-L-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-K-V-H-G-T-A-K-G-C-W-F-A-L-K-R-I-L-K-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-V-S-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-T-S-F-L-F-E-G-K-D-V-E-I-E-G-F-V-P-E-K-G-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-L-Q-W-L-A-T-T-F-I-R-G-Y-Q-I-F-I-S-P-L-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-K-V-H-G-T-A-K-G-C-W-F-A-L-K-R-I-L-K-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-Y-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-V-S-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-E-Q-M-T-S-F-L-F-E-G-K-D-V-E-I-E-G-F-V-P-E-K-G-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-E-T-S-H-S-F-G-A-K-V-L-I-G-A-I-R-I-Y-Q-L-M-I-S-P-L-I-G-P-R-C-R-F-V-P-T-C-S-C-Y-G-I-Q-A-V-K-T-H-G-V-V-K-G-S-W-L-T-V-K-R-I-L-K-C-H-P-F-N-V-G-G-Y-D-P-V-P-P-K-I-N-N-N-K-E-N-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-N-V-F-C-T-Y-L-N-Q-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-Q-A-W-A-E-W-M-K-K-Q-T-M-L-V-N-E-K-K-L-N-M-M-N-S-E-H-R-Q-L-L-E-Q-E-M-T-N-F-L-F-E-G-K-D-V-H-I-E-G-Y-V-P-P-T-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-H-E-S-T-I-L-S-A-G-S-T-N-P-F-N-R-I-V-S-A-V-M-L-A-L-I-E-L-Y-R-R-W-I-S-P-L-I-G-P-R-C-R-F-I-P-T-C-S-A-Y-G-I-E-A-I-Q-R-H-G-P-W-R-G-G-W-L-T-L-R-R-L-L-R-C-H-P-F-T-P-C-G-C-D-P-V-P-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-P-I-L-L-A-L-L-R-I-Y-K-I-A-L-S-P-Y-L-G-S-R-C-R-F-L-P-T-C-S-D-Y-A-R-D-A-V-I-H-H-G-A-A-R-G-S-W-M-A-A-C-R-L-C-R-C-H-P-F-A-Q-G-G-Y-D-P-V-P-G-T-E-A-D-D-T-A-R-P-D-T-H-A-G-R-S-V-H-A-A-A-G-H-A-P-V-A-I-R-L-P-R-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-Q-C-I-K-L-N-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-K-I-W-Q-S-V-S-K-E-A-W-A-G-W-L-K-H-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-A-R-A-R-Q-Y-L-L-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-Q-G-Y-V-P-P-Q-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-S-A-L-H-E-S-R-A-D-T-A-E-A-T-S-S-A-S-S-A-W-K-S-V-R-A-L-P-A-R-T-L-I-F-F-I-E-L-Y-R-T-Y-V-S-P-L-R-M-P-T-C-R-F-M-P-T-C-S-E-Y-A-V-E-S-L-R-T-H-G-V-I-K-G-L-F-L-T-V-V-R-L-A-K-C-A-P-W-H-P-G-G-W-D-P-V-P-A-R-R-D-R-H-A-G-G-R-R-C-C-P-A-N-V-D-E-Q-R-S-T"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-I-F-K-I-F-F-I-L-N-Y-T-I-I-F-L-I-K-I-Y-Q-N-T-F-S-K-L-F-G-Q-Q-C-I-Y-K-P-T-C-S-K-Y-S-I-E-C-L-K-K-Y-N-F-L-T-A-L-V-L-M-T-L-R-T-I-R-C-N-A-L-F-K-G-G-N-D-F-I-P-K-Y-N-P-I-S-T-S-L-K-E-F-Q-K-R-L-I-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-F-I-V-M-I-K-F-Y-R-K-Y-I-S-P-L-K-R-P-C-C-R-F-Y-P-T-C-S-Q-Y-A-L-E-A-I-Q-K-Y-G-A-F-K-G-G-F-M-S-I-G-R-I-L-R-C-N-P-F-C-K-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-N-I-T-D-V-R-I-R-K-I-S-A-E-G-K-M-K-A-I-V-S-V-T-F-E-N-Q-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-F-K-D-I-A-H-P-I-D-T-Q-T-R-E-Q-I-Q-K-A-I-L-D-E-Y-E-K-V-K-N-L-D-M-Q-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-N-R-F-E-I-S-M-L-I-D-Y-Y-G-T-L-L-T-E-K-Q-F-N-V-M-T-L-Y-Y-N-E-D-L-S-L-A-E-I-A-E-I-N-K-T-S-R-Q-A-I-Y-D-L-I-K-R-C-S-K-Q-L-H-S-Y-D-E-K-L-K-L-S-K-K-V-D-K-R-Y-R-I-K-E-E-L-M-A-E-L-N-K-N-S-N-L-D-E-D-I-K-K-Y-I-D-E-K-L-E-E-I-I-N-A"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-S-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-T-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-S-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-F-I-V-M-I-K-F-Y-R-K-Y-I-S-P-L-K-R-P-C-C-R-F-Y-P-T-C-S-Q-Y-A-L-E-A-I-Q-K-Y-G-A-F-K-G-G-F-M-S-I-G-R-I-L-R-C-N-P-F-C-K-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-N-I-T-D-V-R-I-R-K-I-S-A-E-G-K-M-K-A-I-V-S-V-T-F-E-N-Q-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-F-K-D-I-A-H-P-I-N-T-E-T-R-E-Q-I-Q-K-A-I-L-D-E-Y-E-K-V-K-N-L-D-V-Q-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-N-R-F-E-I-S-M-L-I-D-Y-Y-G-T-L-L-T-E-K-Q-F-N-V-M-T-L-Y-Y-N-E-D-L-S-L-A-E-I-A-E-I-N-K-T-S-R-Q-A-I-Y-D-L-I-K-R-C-C-K-Q-L-H-S-Y-D-E-K-L-K-L-S-K-K-I-D-K-R-Y-R-I-K-E-E-L-M-A-E-L-N-K-N-S-N-L-D-E-D-I-K-K-Y-I-D-E-K-L-E-E-I-I-N-A"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-A-R-F-T-S-I-V-L-V-L-S-A-C-F-V-S-S-R-A-Q-F-G-F-F-D-Q-M-F-G-N-Q-G-H-Q-Q-H-Q-E-P-Q-N-V-R-S-D-S-S-W-Y-Q-A-Q-Y-E-G-A-Q-C-T-H-Y-L-C-P-G-T-L-S-C-V-H-F-P-H-H-C-P-C-A-W-E-S-V-E-D-K-A-E-L-G-D-G-I-A-I-C-G-S-K-G-G-W-K-E-G-E-F-A-K-K-V-E-L-A-R-K-G-V-L"} +{"text": "### FUNCTION Part of the gene cluster that mediates the biosynthesis of elsinochrome C, a perelyenequinone phytotoxin structurally similar to cercosporin ### SEQUENCE -M-A-L-M-I-E-K-L-A-P-P-S-K-R-S-M-T-K-F-T-Q-H-C-T-G-N-C-G-Q-F-W-P-K-T-W-F-W-S-R-S-S-F-I-H-W-R-L-V-S-R-H-W-P-L-A-P-F-Q-L-P-K-T-T-M-A-Y-A-L-V-N-T-K-L-S-A-L-R-D-I-G-N"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-R-K-Y-Q-S-D-M-E-G-L-P-R-P-P-F-P-G-P-K-G-Q-D-I-F-D-H-V-S-Q-Q-A-W-K-E-W-L-H-E-Q-T-M-L-I-N-E-K-H-L-N-V-M-D-P-E-A-K-R-F-L-D-E-Q-R-D-R-F-L-N-N-E-N-Y-E-K-A-E-G-Y-V-P-P-A-H-D-A-N-K"} +{"text": "### FUNCTION Imparts immunity to bacteriocin hiracin-JM79 to naturally sensitive host strains ### SEQUENCE -M-D-F-T-K-E-E-K-L-L-N-A-I-S-K-V-Y-N-E-A-T-I-D-D-Y-P-D-L-K-E-K-L-F-L-Y-S-K-E-I-S-E-G-K-S-V-G-E-V-S-M-K-L-S-S-F-L-G-R-Y-I-L-K-H-K-F-G-L-P-K-S-L-I-E-L-Q-E-I-V-S-K-E-S-Q-V-Y-R-G-W-A-S-I-G-I-W-S"} +{"text": "### FUNCTION In leeches, the angiotensins are involved in diuresis ### SEQUENCE -D-R-V-Y-I-H-P-F-H-L-L-X-W-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-V-L-L-V-R-L-I-K-G-Y-K-I-F-I-S-P-I-L-P-P-S-C-R-F-Q-P-T-C-S-E-Y-A-M-E-A-I-E-R-F-G-I-F-K-G-T-A-M-A-V-M-R-I-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P-P-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-L-P-A-G-Y-S-R-N-W-S-G-P-W-P-K-T-P-G-R-V-L-G-T-A-F-V-R-L-Y-Q-L-T-L-S-G-F-I-G-N-S-C-R-H-F-P-T-C-S-E-Y-A-Y-E-A-I-A-R-H-G-L-W-A-G-G-W-M-G-L-F-R-V-M-H-C-G-P-G-G-T-H-G-I-D-P-V-P-E-I-L-Q-P-R-H-A-W-W-A-P-W-R-L-W-K-L-K-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-K-K-E-F-F-T-G-A-V-K-Q-V-F-I-I-P-V-K-I-Y-Q-Y-S-I-S-P-L-L-P-G-A-C-R-Y-T-P-T-C-S-E-Y-C-V-Q-A-I-E-K-Y-G-P-L-K-G-I-W-L-G-T-K-R-I-C-S-C-N-P-W-G-G-S-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-K-C-I-K-L-G-R-E-A-E-G-L-D-F-P-P-Y-P-G-P-L-G-K-R-L-W-E-E-V-S-K-E-A-W-A-D-W-M-K-Q-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-Q-Y-L-A-R-Q-M-E-K-H-F-F-G-D-G-A-D-A-V-Q-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-A-Q-S-P-L-Q-W-L-A-T-T-V-I-R-G-Y-Q-L-F-I-S-P-L-M-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-K-L-H-G-T-A-K-G-S-W-F-A-L-K-R-I-L-R-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-N-V-N-C-V-Y-L-N-K-E-A-P-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-L-W-Q-Q-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-L-E-D-R-Q-F-L-E-Q-Q-M-I-N-F-L-F-E-G-K-Q-V-E-I-E-G-Y-V-P-P-V-E-D"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-L-I-T-S-S-R-K-P-S-A-N-T-R-T-M-C-K-Y-L-A-S-F-F-N-C-K-Y-M-T-R-G-K-M-G-L-I-D-I-V-S-L-C-E-N-G-L-L-M-V-V-G-D-Y-H-G-S-P-G-S-I-M-F-Y-D-S-H-G-V-E-L-L-S-I-H-L-S-V-F-Y-P-D-G-Y-K-Y-T-P-L-K-A-L-E-P-S-I-N-G-D-G-E-L-F-N-L-L-S-Y-Y-L-D-I-P-E-G-E-C-Y-Y-D-S-K-C-L-I-A-S-D-D-H-L-E-F-V-Y-L-D-N-M-L-F-R-L-N-I-K-N-Y-R-K-M-V-M-S-E"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-S-G-S-F-D-R-Y-V-S-F-K-N-C-D-W-K-V-R-S-E-R-V-M-A-R-L-Q-R-H-I-D-A-A-E-N-P-F-W-A-Y-F-A-Q-K-R-T-E-L-R-E-K-Q-G-L-D-D-L-R-V-L-H-N-Y-L-P-T-L-R-E-L-L-E-D-N-G-D-L-E-T-L-A-M-L-E-E-L-E-V-N-L-M"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-V-L-I-A-L-L-R-F-Y-K-V-A-V-S-P-M-L-G-N-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-A-R-R-I-C-R-C-H-P-F-S-A-G-G-I-D-L-V-P-P-P-T-S-E-K-R"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-M-V-Q-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-S-I-S-K-E-A-W-Q-A-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-F-F-F-G-E-G-A-D-T-A-Q-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION May have a potential role in hypercalcemia of malignancy ### SEQUENCE -M-A-Q-G-Q-R-K-F-Q-A-Q-K-P-A-K-S-K-A-A-A-A-A-A-S-A-R-N-R-G-P-R-K-G-G-R-V-I-A-P-K-K-A-R-I-V-Q-Q-Q-Q-L-K-K-N-L-E-V-G-I-R-K-K-I-E-H-D-V-V-M-K-A-S-T-S-L-P-K-K-L-A-L-L-K-A-S-T-K-K-K-E-A-S-S-S-T-K-M-P-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-T-S-T-V-N-Q-S-L-D-D-F-M-G-R-F-A-A-F-V-K-E-H-A-E-A-G-A-I-E-Y-D-E-D-W-P-S-P-C-Y-A-T-D-V-T-P-E-S-G-T-S-I-P-W-K-P-V-L-R-E-Q-T-S-E-F-K-D-L-S-E-A-L-E-L-T-L-H-P-D-V-A-Q-F-Y-S-R-Y-W-S-D-N-I-V-A-Q-H-P-S-G-K-L-Q-I-L-Q-A-W-N-E-E-D-F-E-R-L-Q-Q-N-I-V-G-H-I-L-M-K-R-R-L-R-Q-P-E-T-I-F-I-A-L-T-D-E-D-D-F-V-L-S-V-D-N-Q-T-G-A-V-M-L-E-Q-V-G-L-Q-P-K-E-Q-I-S-P-D-L-A-T-F-L-D-E-I-E-P-T-T-T-D"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-Q-H-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-K-I-F-D-N-I-S-K-E-A-W-T-E-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-E-P-T-A-R-N-F-L-E-T-Q-M-Q-A-Y-L-F-E-G-K-E-P-D-I-E-G-Y-V-P-P-K-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-P-L-A-H-L-L-A-L-P-V-R-A-Y-R-L-I-F-S-P-W-V-G-Y-N-C-R-Y-Q-P-T-C-S-A-Y-A-L-E-A-L-Q-K-H-G-G-L-I-G-A-W-L-T-L-R-R-I-L-R-C-H-P-W-G-K-C-G-Y-D-P-V-P-E-R-T-R-K-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-G-R-L-V-I-L-V-L-R-A-Y-Q-R-F-V-S-P-L-F-P-P-S-C-R-F-T-P-S-C-S-Q-Y-A-V-E-A-V-E-R-Y-G-P-L-K-G-G-A-M-A-A-W-R-V-L-R-C-H-P-F-S-R-G-G-V-D-P-V-R"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-G-N-I-V-Y-F-S-S-V-S-E-N-T-H-R-F-V-E-K-L-E-L-P-A-T-R-I-P-I-L-G-R-I-Q-D-P-D-F-V-R-E-P-Y-V-L-V-L-P-T-Y-G-G-G-H-A-N-G-P-D-P-D-A-G-G-Y-V-P-K-Q-V-I-A-F-L-N-N-E-H-N-R-S-L-I-R-G-V-I-A-A-G-N-T-N-F-G-A-E-F-G-Y-A-G-D-V-V-S-R-K-C-G-V-P-Y-L-Y-R-F-E-L-M-G-T-T-D-D-V-L-A-V-R-A-G-L-E-N-F-W-K-E-Q-T-C-H-P-P-S-Q-L-Q-S-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-Q-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-S-V-S-K-E-A-W-Q-G-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-D-G-A-D-Q-A-S-G-Y-V-P-P-T-E-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-V-L-I-A-L-L-R-F-Y-K-V-A-V-S-P-M-L-G-N-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-V-R-R-V-C-R-C-H-P-F-S-A-G-G-V-D-L-V-P-P-P-N-S-D-T-R-A-R-G-E-A-D-A-R-S-H-R-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-P-L-S-P-G-S-R-I-L-I-G-L-I-R-G-Y-Q-L-V-I-S-P-L-L-G-P-R-C-R-F-H-P-T-C-S-H-Y-G-I-E-A-L-R-R-F-G-M-I-K-G-S-W-L-T-L-K-R-V-L-K-C-H-P-L-N-S-G-G-D-D-P-V-P-P-K-L-D-D-N-R-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-L-N-I-S-T-A-L-R-S-F-T-Q-R-Y-I-D-L-W-Q-Q-Q-T-G-H-L-P-A-S-K-E-L-Y-G-V-P-S-P-C-I-V-E-T-G-E-D-Q-V-F-W-Q-P-Q-A-F-L-P-E-A-T-L-T-N-I-E-R-A-L-E-I-Q-L-H-P-D-I-H-D-F-Y-T-Q-Q-Y-A-G-D-M-M-A-D-L-G-N-H-R-F-T-L-L-Q-V-W-S-E-D-D-F-I-R-L-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-L-F-L-A-T-T-S-S-E-M-T-M-A-S-L-C-N-V-S-G-N-V-V-L-E-Q-F-G-S-D-K-R-T-L-L-A-S-T-L-S-H-F-L-D-A-L-R-P-V-L-P-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-K-K-D-A-E-R-Q-D-F-Q-L-Y-P-G-E-I-G-K-R-I-Y-N-E-I-S-K-E-A-W-S-Q-W-I-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-I-E-D-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-Q-D-V-H-I-A-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-P-L-S-P-G-S-R-I-L-I-G-L-I-R-G-Y-Q-L-V-I-S-P-L-L-G-P-R-C-R-F-H-P-T-C-S-H-Y-G-I-E-A-L-R-R-F-G-M-I-K-G-S-W-L-T-L-K-R-V-L-K-C-H-P-L-N-S-G-G-D-D-P-V-P-P-K-L-D-D-N-R-E-H"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-K-K-D-A-E-R-Q-D-F-Q-L-Y-P-G-E-I-G-K-R-I-Y-N-E-I-S-K-E-A-W-S-Q-W-I-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-I-E-D-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-Q-D-V-H-I-A-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-L-N-I-S-T-A-L-R-S-F-T-Q-R-Y-I-D-L-W-Q-Q-Q-T-G-H-L-P-A-S-K-E-L-Y-G-V-P-S-P-C-I-V-E-T-G-E-D-Q-V-F-W-Q-P-Q-A-F-L-P-E-A-T-L-T-N-I-E-R-A-L-E-I-Q-L-H-P-D-I-H-D-F-Y-T-Q-Q-Y-A-G-D-M-M-A-D-L-G-N-H-R-F-T-L-L-Q-V-W-S-E-D-D-F-I-R-L-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-L-F-L-A-T-T-S-S-E-M-T-M-A-S-L-C-N-V-S-G-N-V-V-L-E-Q-F-G-S-D-K-R-T-L-L-A-S-T-L-S-H-F-L-D-A-L-R-P-V-L-P-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-N-N-K-T-P-F-L-S-A-I-F-T-A-S-I-R-G-Y-Q-R-F-F-S-A-F-T-P-S-S-C-R-F-Y-P-T-C-S-N-Y-A-L-W-L-L-C-F-E-N-P-L-S-A-M-G-K-I-A-I-R-I-L-S-C-N-P-F-C-S-G-G-I-A-Y-P-T-T-R-L-K-R-P-S-L-L-Q-S-H-K-D-F-N-R-N-F-K-T-I-T-F-W-L-V-P-T-T-K-S-R-T-T-Y-Y-I-I-K-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-P-L-A-F-V-I-S-L-P-I-R-F-Y-R-K-F-L-G-P-L-L-P-K-V-C-R-F-H-P-S-C-S-T-Y-A-M-E-A-L-E-K-H-G-G-L-K-G-S-W-L-T-L-W-R-L-V-R-C-Q-P-F-H-P-G-G-I-D-P-V-P"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-N-I-T-D-V-R-V-F-P-V-E-E-D-K-L-K-A-Y-V-T-I-T-L-D-H-C-F-V-I-R-D-L-K-V-I-H-G-S-T-G-L-F-I-A-M-P-A-K-K-R-K-D-G-T-Y-K-D-I-A-H-P-L-N-A-D-T-R-S-Q-M-E-R-V-I-L-M-E-Y-E-R-H-L-H-Q-A-Q-A-G-M-L-V-A-A-P-A-D-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-Q-I-M-I-L-L-V-R-F-Y-Q-R-A-I-S-P-I-L-P-D-S-C-C-F-Y-P-T-C-S-S-Y-M-I-T-A-L-E-K-Q-G-P-L-L-G-L-L-M-G-L-A-R-I-L-R-C-N-P-F-N-R-G-G-V-D-P-V-P-D-K-F-T-L-L-R-N-P-H-P-E-E-Y-E-D-E-I-I-A-R-K-F-H-S-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-L-L-A-R-L-I-A-L-P-V-R-G-Y-R-L-L-F-S-P-W-V-G-F-N-C-R-Y-Q-P-T-C-S-A-Y-A-L-D-A-L-E-R-H-G-P-F-K-G-T-Y-L-M-L-R-R-I-G-R-C-H-P-F-G-G-S-G-Y-D-P-V-P-G-A-D-P-K-H-D-R-C-C-G-R-T-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-A-R-L-L-I-L-I-A-R-A-W-Q-L-G-P-S-R-V-L-P-P-T-C-R-Y-A-P-S-C-S-E-Y-A-I-V-A-L-R-R-H-G-A-I-K-G-G-W-I-A-T-K-R-L-L-R-C-H-P-W-G-G-H-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-A-R-L-L-V-G-L-I-K-L-Y-Q-W-T-L-S-P-L-L-G-Q-R-C-R-F-Y-P-T-C-S-Q-Y-A-V-E-A-I-Q-K-H-G-A-W-R-G-A-F-F-T-I-C-R-L-S-K-C-H-P-W-H-D-G-G-H-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-L-A-L-V-P-I-Q-F-Y-R-Y-A-I-S-P-L-M-A-S-H-C-R-F-Y-P-S-C-S-C-Y-A-Y-E-A-I-E-N-H-G-L-L-R-G-G-W-L-A-V-R-R-L-G-R-C-H-P-W-N-D-G-G-F-D-P-V-P-P-A-P-S-S-R-T-S-S-I-A-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-K-C-R-K-Y-N-E-E-L-P-G-L-D-R-P-P-Y-P-G-A-K-G-Q-D-I-F-E-H-I-S-Q-K-A-W-K-E-W-Q-D-H-Q-T-M-L-I-N-E-K-R-L-N-M-M-N-A-E-D-R-K-F-I-Q-A-E-M-D-K-F-F-A-G-E-D-Y-A-Q-A-E-G-Y-V-P-P-S-N"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-S-S-T-L-I-V-Q-L-D-M-R-T-L-C-Q-E-A-D-V-S-A-D-W-V-I-E-I-V-E-H-G-I-V-E-P-S-G-R-T-P-E-E-W-V-F-D-D-R-A-P-V-T-L-K-R-A-V-K-L-H-Q-E-L-E-L-E-W-E-G-V-A-L-A-L-E-L-L-E-E-V-Q-Q-L-R-S-E-N-S-M-L-K-Q-R-L-G-R-F-T-Q-M"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-H-M-V-K-C-V-K-L-G-R-E-A-E-G-L-E-E-P-P-F-D-S-E-L-G-Q-K-I-Y-N-N-V-S-A-E-A-W-R-G-W-T-E-H-Q-K-M-L-L-N-E-Y-R-L-Q-P-W-K-K-E-H-Q-E-F-L-V-Q-Q-M-E-A-Y-F-F-G-E-G-S-E-A-P-K-E-F-V-P-P-S-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-A-V-L-V-Q-M-L-K-G-Y-K-R-W-I-S-P-L-L-P-V-S-C-R-Y-V-P-T-C-S-E-Y-A-M-E-A-I-S-I-H-G-A-V-R-G-S-V-L-A-L-G-R-L-L-R-C-H-P-F-V-R-G-G-Y-D-P-V-P-R-S-H-S-C-C-D-D-K-I-S-T-T-A-H-D-A-V-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-A-A-A-R-G-L-V-R-L-V-K-S-Y-Q-R-H-L-S-P-R-K-P-A-P-T-C-R-F-T-P-T-C-S-Q-Y-A-V-E-A-I-E-R-H-G-A-L-K-G-A-W-L-A-A-W-R-V-L-R-C-N-P-L-V-P-G-G-C-D-P-V-P-E-H-F-P-S-W-R-G-P-H-P-K-T-P-S-R-K-T-P-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-N-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-P-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-Q-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-N-K-P-T-T"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-S-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-H-L-E-H-E-T-V-A-K-N-P-S-K-Q-R-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-A-G-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-A-E-K-A"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-N-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-P-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-Q-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-K-Q-T-N-N-L-I-T-E-R-T-H-P-C-H-K-P-M-R-H-T-S-H"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-S-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-H-L-E-H-E-T-V-A-K-N-P-S-K-Q-R-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-A-G-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-A-E-K-A"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-N-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-P-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-R-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-K-Q-T-N-N-L-I-T-E-R-T-H-P-C-H-K-P-M-R-H-T-S-H"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-S-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-H-L-E-H-E-T-V-A-K-N-P-S-K-Q-R-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-A-G-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-A-E-K-A"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-N-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-P-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-Q-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-K-Q-T-N-N-L-I-T-E-R-T-H-P-C-H-K-P-M-R-H-T-S-H"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-S-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-H-L-E-H-E-T-V-A-K-N-P-S-K-Q-R-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-A-G-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-A-E-K-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-H-C-I-K-L-N-K-E-A-E-G-L-D-F-P-P-L-P-G-D-L-G-K-K-I-W-Q-N-V-S-K-E-A-W-A-G-W-L-K-H-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-I-K-Q-T-E-K-Y-F-F-G-D-G-A-D-Q-A-A-G-Y-V-P-P-P-A-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-K-N-I-Y-C-V-F-L-R-K-Q-A-E-G-Q-D-F-Q-S-Y-P-G-E-L-G-K-H-I-F-N-N-I-S-K-E-A-W-A-K-W-Q-Q-K-Q-T-M-L-I-N-E-N-K-L-N-L-I-S-N-T-D-R-N-F-L-E-K-E-M-I-K-F-L-F-K-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-L-L-S-P-I-I-K-L-L-S-Y-V-I-R-C-Y-Q-L-I-I-S-P-L-I-K-P-H-C-R-F-L-P-T-C-S-Q-Y-S-I-T-A-I-H-R-F-G-I-F-K-G-I-W-L-T-L-I-R-I-L-R-C-N-P-W-S-Q-G-G-E-D-Q-V-P-L-N-I-F-D-K-R-E-Y"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-G-L-I-V-Y-Y-S-S-R-S-E-N-T-H-R-F-V-A-K-L-G-L-R-A-A-R-I-P-P-S-G-A-A-G-A-F-H-I-R-E-P-F-V-L-I-V-P-T-Y-S-G-D-G-G-K-G-A-V-P-K-Q-V-I-R-F-L-N-D-A-E-N-R-G-H-I-R-G-V-I-A-A-G-N-S-N-F-G-E-T-Y-G-L-A-G-D-V-V-S-Q-K-C-Q-V-P-Y-L-Y-R-F-E-L-L-G-T-E-A-D-V-A-N-V-K-H-G-M-E-R-F-W-T-R-E-H-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-L-F-I-K-I-I-N-K-Y-L-Y-K-L-I-Y-N-F-I-D-F-Y-Q-K-I-I-S-P-I-L-P-A-R-C-R-Y-Y-P-T-C-S-N-Y-G-K-Q-A-L-A-W-H-G-V-L-N-G-S-L-L-L-L-K-R-I-S-R-C-H-P-L-G-G-H-G-V-D-F-V-P-L-P-L-A-S-Y-R-Y-Q-Y-L-S-C-N-P-V-A-H-G-Q-F-H-G-F-Y-V-Y-R-D-N-H-G-Y-V-T-R-L-N-H-M-M-K-L-T"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-E-T-F-N-P-Q-A-N-T-V-F-C-R-K-Y-Q-Q-E-L-P-K-M-P-H-P-P-F-P-N-K-K-G-Q-E-L-Q-E-T-V-S-E-K-A-W-K-E-W-L-E-Q-Q-T-M-L-I-N-E-N-H-L-S-M-L-D-P-K-A-K-Q-F-L-T-E-Q-R-D-K-F-L-D-N-E-D-Y-E-R-A-Q-G-W-T-P-E-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-P-T-R-Q-S-S-I-H-C-A-D-C-A-R-A-A-L-R-L-P-R-N-S-G-R-A-L-I-W-I-Y-R-H-T-L-S-P-L-V-G-F-N-C-R-H-L-P-T-C-S-V-Y-G-D-E-A-I-E-R-F-G-L-W-G-G-G-W-M-T-L-A-R-L-L-R-C-Q-P-W-G-T-S-G-I-D-N-V-P-A-T-K-P-P-G-A-S-W-Y-R-P-W-R-Y-G-R-W-R-G-V-N-A-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-P-G-K-R-R-P-L-T-R-L-P-F-A-L-L-S-W-G-M-I-G-L-L-R-V-Y-Q-Y-G-I-S-P-L-L-G-P-R-C-R-F-W-P-S-C-S-Q-Y-A-V-E-A-I-Q-V-H-G-P-L-K-G-A-W-L-A-L-K-R-I-V-K-C-H-P-G-H-P-G-G-V-D-P-V-P-P-G-P-H-E-T-P-R-K-T-S-T-H-D-D-E-P-P-S-R"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-D-T-V-F-C-R-K-Y-Q-K-E-L-D-A-L-P-F-P-P-L-P-G-A-K-G-Q-E-I-Q-Q-T-V-S-K-Q-A-W-D-E-W-Q-A-L-Q-T-R-L-I-N-E-K-H-L-S-L-L-D-P-D-A-R-A-Y-L-M-E-Q-M-E-R-F-L-D-N-R-E-T-D-Q-A-E-G-Y-V-P-P-S-Q"} +{"text": "### FUNCTION Makes mgtA transcription sensitive to intracellular proline levels Under low levels of proline this protein cannot be fully translated, and a stem loop forms which permits transcription of the downstream mgtA gene ### SEQUENCE -M-E-P-D-P-T-P-L-P-R-R-R-L-K-L-F-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-S-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-S-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-R-I-L-L-L-L-L-T-F-Y-R-Y-F-I-S-P-L-L-G-G-N-N-C-R-F-Y-P-T-C-S-K-Y-A-K-E-A-L-N-T-H-G-G-I-K-G-L-W-L-I-F-K-R-I-I-K-C-Q-P-L-C-D-G-G-Y-D-P-V-P-L-T-K"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-R-E-L-Y-D-S-F-E-E-L-E-K-Q-T-K-F-T-L-S-Q-I-E-R-I-K-A-E-M-G-K-V-I-E-K-N-A-E-L-E-I-E-N-Q-H-L-R-E-H-L-H-E-I-E-Q-K-Q-K-G-N-K-E-G-T-E-L-S-K-S-R-K-N-L-E-K-L-Y-E-E-G-F-H-V-C-N-V-D-N-M-Y-G-S-R-R-V-N-D-E-P-C-V-F-C-Q-D-V-I-Y-G-D-R-H"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-A-I-E-K-T-N-R-I-N-A-L-F-D-F-Y-E-P-L-L-T-P-K-Q-M-T-Y-I-G-L-Y-Y-R-D-D-Y-S-L-G-E-I-A-E-N-Y-E-V-S-R-Q-A-V-Y-D-N-I-R-R-T-E-K-I-L-E-E-Y-E-S-K-L-H-L-Y-R-N-F-Q-L-Q-S-E-E-L-D-N-L-L-K-Y-V-E-E-N-Y-A-Y-D-K-E-L-L-T-R-I-N-R-L-E-S-L-E-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-I-L-K-N-Q-I-N-K-G-I-I-F-L-I-R-C-Y-Q-K-Y-I-S-P-M-F-P-P-T-C-R-Y-Y-P-T-C-S-N-Y-A-I-D-A-I-K-K-H-G-I-V-K-G-I-I-M-G-I-F-R-I-L-R-C-N-P-F-V-E-G-G-V-D-V-V-P-E-K-F-T-I-F-R-N-D-D-K"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-N-V-P-F-D-R-Y-V-S-F-K-N-A-D-W-E-G-K-S-Q-R-V-M-A-K-L-Q-S-H-I-D-A-A-D-N-P-F-W-G-Y-F-A-K-K-R-T-E-L-N-E-K-Q-G-L-D-D-L-R-V-L-H-N-Y-L-P-T-L-R-E-I-L-E-E-S-G-D-D-E-T-L-A-M-L-E-D-L-E-V-T-C-M"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-L-A-I-D-C-P-D-C-R-K-M-I-L-A-L-P-R-R-A-G-R-G-A-I-W-L-Y-R-H-S-L-S-P-L-V-G-Y-H-C-R-H-L-P-T-C-S-S-Y-G-D-E-A-I-E-R-F-G-L-W-A-G-G-W-M-T-L-A-R-L-L-R-C-Q-P-W-G-T-H-G-I-D-N-V-P-L-T-A-P-A-G-A-R-W-Y-L-P-W-R-Y-A-R-W-R-G-V-N-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-E-A-C-C-K-K-S-R-K-A-N-S-D-P-T-R-K-N-W-L-N-L-P-L-L-A-L-I-K-V-Y-R-Y-A-I-S-P-L-L-G-P-R-C-R-F-E-P-T-C-S-S-Y-A-E-Q-A-L-I-E-H-G-P-F-K-G-T-M-L-A-L-S-R-L-S-K-C-H-P-W-H-A-G-G-Y-D-P-V-P-K-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-N-C-R-K-F-K-Q-E-L-E-G-L-D-F-P-P-M-P-G-A-K-G-Q-D-I-F-E-N-V-S-K-K-A-W-Q-E-W-L-S-H-Q-T-M-L-I-N-E-K-H-L-N-M-M-D-L-T-D-R-T-Y-L-N-Q-Q-M-D-K-F-L-S-G-E-E-Y-D-Q-A-E-G-Y-V-A-P-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-R-D-V-L-V-G-I-V-K-G-Y-R-L-L-L-S-P-W-L-G-S-S-C-R-F-E-P-T-C-S-A-Y-S-L-Q-A-L-Q-T-H-G-A-A-A-G-S-Y-L-T-L-T-R-L-A-R-C-H-P-W-C-A-G-G-S-D-P-V-P-S-E-K-P-R-F-K-S-Q-L-F-T-Q-L-I-H-P-S-S-E-K-K-S-S"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-I-K-L-G-K-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-K-R-I-W-E-S-V-S-K-Q-A-W-A-D-W-L-K-H-Q-T-M-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-Q-Y-L-A-R-Q-M-E-N-H-F-F-G-G-G-A-D-A-A-Q-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-M-K-R-L-L-I-G-M-I-R-I-Y-Q-R-Y-I-S-P-L-K-R-P-S-C-R-F-Y-P-T-C-S-E-Y-S-I-Q-A-I-Q-K-Y-G-V-V-K-G-C-W-K-S-L-V-R-I-L-K-C-H-P-F-H-P-G-G-Y-D-P-V"} +{"text": "### FUNCTION Probable transcription factor that function in the regulation of cell-specific gene expression during drosophila development, particularly in the differentiation of the nervous system ### SEQUENCE -W-A-D-L-N-T-N-N-L-D-D-P-G-A-F-Y-G-V-T-S-V-Y-E-S-N-E-N-M-T-I-T-C-S-T-K-V-C-S-F-G-K-Q-V-V-E-K-V-E-T-E-Y-A-R-N-E-G-G-R-F-V-Y-R-I-Q-R-S-P-M-C-E-Y-M-V-N-F-I-H-K-L-K-H-L-P-E-K-Y-M-M-N-S-V-L-E-N-F-T-I-L-Q-V-V-S-N-R-D-T-Q-E-T-L-L-C-A-A-F-V-F-E-V-S-N-S-E-H-G-A-Q-H-H-I-Y-R-L-V-K-T"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-F-K-S-L-L-K-N-L-P-K-F-F-F-L-G-L-I-H-I-Y-R-W-T-I-S-P-L-L-G-S-P-C-R-F-F-P-T-C-S-Q-Y-A-L-Q-A-L-K-H-H-G-C-I-K-G-L-G-F-T-I-K-R-I-G-K-C-G-P-W-H-P-G-G-V-D-L-V-P-M-T-T-L-E-E-S-L-D-I-S-P-A-T-N-D-D-D-S-C-D-S-Q-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-P-A-A-F-L-I-S-L-P-I-R-F-Y-R-L-V-I-S-P-M-I-A-S-N-C-R-Y-T-P-T-C-S-S-Y-A-M-E-A-L-R-K-H-G-A-I-K-G-T-W-L-A-A-R-R-V-S-R-C-H-P-W-G-G-S-G-I-D-N-V-P-D"} +{"text": "### FUNCTION May play a role in ciliary assembly ### SEQUENCE -M-T-S-L-F-T-Q-E-I-R-L-S-K-R-H-E-K-I-V-S-Q-R-L-M-L-L-Q-Q-M-E-N-K-P-E-D-Q-N-K-G-R-A-S-Q-T-Q-A-A-K-A-A-L-Q-R-N-V-S-L-L-K-D-I-E-A-A-E-K-S-L-Q-T-R-M-Y-P-A-L-P-P-E-V-A-A-L-E-T-L-Y-W-A-S-V-E-E-Y-I-P-K-W-E-Q-F-L-L-G-R-A-P-Y-P-A-C-S-E-N-G-N-E-A-E-D-T-I-P-K-R-A-Q-Q"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-K-V-F-C-K-K-Y-H-Q-E-L-D-A-I-P-F-Q-P-L-P-G-E-L-G-K-K-I-H-N-E-I-S-N-K-A-W-Q-A-W-L-A-H-Q-T-I-L-I-N-E-Y-R-L-N-L-I-E-P-K-A-K-E-F-L-K-E-E-M-Y-K-F-L-F-E-G-K-E-E-K-P-E-Q-F-S-E-I"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-F-F-K-K-I-T-L-I-P-F-V-M-L-I-N-L-Y-R-Y-C-I-S-P-F-I-P-A-R-C-R-Y-Y-P-T-C-S-E-Y-A-L-E-A-L-K-T-H-G-I-L-K-G-L-Y-L-T-T-R-R-L-L-R-C-H-P-L-S-K-R-D-Y-Y-D-L-V-P-C-K-N-K-K-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Accessory element involved in the expression of sarA and several virulence factors Modulates SarA production and/or function in a strain-dependent manner Affects the transcription of the accessory gene regulator ### SEQUENCE -M-K-Y-L-I-L-S-L-V-A-N-L-L-V-F-G-V-L-S-A-I-G-L-N-I-N-I-L-A-A-M-M-I-V-L-V-I-P-I-M-I-S-G-I-L-F-F-K-T-N-I-D-K-T-Y-I-F-F-N-I-I-F-I-D-F-Y-Y-Y-I-Y-N-V-H-L-M-T-L-P-K-F-N-N-Y-I-K-A-E-M-M-E-L-E-D-I-D-V-L-I-T-S-K-D-F-G-F-D-E-I-L-F-Y-T-L-Y-L-L-L-I-L-I-V-L-Y-Y-L-K-K-Q-V-K-H-K-I"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-R-L-F-E-E-S-N-E-D-V-V-E-I-Q-R-A-N-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-A-T-G-Y-I-N-H-L-L-Q-L-I-G-P-S-I-S-Q-Q-Q-A-Y-Y-I-I-D-G-L-L-D-K-M-L-I-N-E-R-E-A-K-M-I-Q-A-V-I-D-R-E-T-L-S-M-D-M-V-S-R-D-I-I-R-A-N-I-L-K-R-L-L-P-V-I-N-Y-Y"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-V-P-D-K-N-A-T-S-E-D-S-E-E-A"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-L-L-I-L-I-A-R-A-W-Q-L-G-P-S-R-V-L-P-P-S-C-R-Y-S-P-S-C-S-Q-Y-A-I-E-A-L-E-K-H-G-A-I-K-G-G-W-L-A-A-K-R-L-L-R-C-H-P-W-G-G-H-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-R-R-A-L-V-L-L-V-R-I-Y-Q-R-L-V-S-P-L-L-P-P-A-C-R-F-Y-P-S-C-S-A-Y-A-V-T-A-L-Q-R-H-G-A-L-R-G-S-W-L-T-V-R-R-L-C-R-C-H-P-F-H-P-G-G-V-D-P-V-P-E-L-T-P-K-R"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-M-C-K-K-L-G-R-E-L-P-G-L-A-Y-K-P-F-P-N-E-L-G-Q-R-I-Y-D-S-I-S-Q-D-A-W-K-L-W-L-E-H-F-K-M-I-L-N-E-Y-R-L-S-P-A-D-P-R-T-T-E-I-L-F-Q-Q-A-E-Q-F-F-F-G-E-N-A-Q-L-P-P-D-Y-R-P-P-P-S-K-G"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-I-T-E-V-R-V-F-P-V-N-E-E-K-L-K-A-Y-V-T-I-T-L-D-H-C-F-V-I-R-D-L-K-V-I-H-G-N-T-G-L-F-I-A-M-P-A-K-R-R-K-D-G-T-F-K-D-I-A-H-P-L-N-S-D-T-R-E-K-M-E-R-T-I-L-A-E-Y-D-R-E-L-K-K-G-A-A-A-P-A-R-A-T-G-T-D-P-H-E-D"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-S-G-S-F-D-R-Y-V-S-F-K-N-S-N-W-E-V-R-S-E-R-V-M-A-R-L-Q-K-H-I-D-A-A-E-N-P-F-W-A-Y-F-A-Q-K-R-I-E-L-R-E-K-Q-G-L-D-D-L-R-V-L-H-N-Y-L-P-T-L-R-E-L-L-E-D-N-G-D-L-E-T-L-A-M-L-E-E-L-E-V-T-L-M"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-H-S-R-L-P-T-H-A-A-D-L-L-Q-A-L-S-R-L-P-R-N-A-G-R-G-L-I-W-V-Y-R-H-S-F-S-A-L-V-G-S-N-C-R-H-L-P-T-C-S-Q-Y-G-D-E-A-I-G-R-F-G-L-W-A-G-G-W-M-T-L-A-R-L-I-R-C-N-P-Y-G-T-S-G-I-D-N-V-P-E-T-P-P-P-G-A-R-W-Y-L-P-W-R-Y-A-R-W-R-G-V-N-G-P-D-C-G-C-G-H-H-D-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-P-E-R-S-D-P-L-T-R-S-L-I-A-L-I-R-G-Y-Q-V-G-I-S-P-W-L-P-P-A-C-R-Y-Y-P-T-C-S-Q-Y-T-L-E-A-V-R-R-Y-G-A-L-R-G-G-W-L-G-I-R-R-L-C-R-C-H-P-W-H-P-G-G-Y-D-P-V-P-D-L-P-G-S-A-P-T-Q-K-P-F-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-E-R-S-D-P-L-T-R-G-L-V-A-L-I-R-G-Y-Q-V-A-I-S-P-L-L-P-P-A-C-R-Y-Y-P-T-C-S-Q-Y-T-L-E-A-V-R-R-Y-G-A-I-R-G-S-W-L-G-I-R-R-L-C-R-C-H-P-W-H-P-G-G-Y-D-P-V-P-D-L-P-G-S-A-P-E-E-N-G-R-P-S-P-D-G-Q-H-S-G-S-G-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-C-E-F-C-V-R-Q-A-D-D-E-D-D-G-G-A-A-A-S-G-R-P-N-A-R-T-A-R-Y-S-R-N-Y-A-G-P-F-R-K-T-P-D-R-L-L-G-M-G-L-I-R-L-Y-Q-L-T-L-S-G-F-V-G-N-S-C-R-H-I-P-T-C-S-E-Y-G-Y-E-A-I-A-R-H-G-L-W-A-G-G-W-M-T-L-F-R-V-A-R-C-G-P-G-G-T-S-G-L-D-P-V-P-E-I-L-S-D-G-F-R-W-W-T-P-R-R-Y-L-S-L-G-R-K-R-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-K-L-K-R-E-A-E-G-L-D-Y-P-P-Y-P-G-E-L-G-A-R-I-W-R-E-I-S-K-E-S-W-E-E-W-K-Q-I-Q-T-R-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-K-Y-L-Q-Q-Q-M-E-R-F-L-F-E-D-G-T-V-E-A-Q-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-I-I-Y-R-D-L-F-S-G-D-E-L-C-S-D-T-F-P-M-K-L-V-N-D-V-V-F-E-F-T-G-K-H-V-V-R-K-L-G-E-V-T-L-E-G-A-N-P-S-A-E-E-F-D-E-G-T-E-E-Q-M-E-S-G-I-D-I-V-L-N-H-Q-L-M-E-M-P-M-Y-Q-D-I-K-I-F-K-D-W-I-K-E-Y-M-K-K-L-V-E-K-M-K-S-D-G-E-S-E-E-S-I-S-K-F-K-K-N-M-Q-E-Y-V-T-S-L-L-K-K-D-R-F-K-E-L-Q-F-F-S-G-P-G-E-N-A-A-E-G-Q-L-A-I-V-E-Y-R-Q-V-S-D-T-E-Q-P-I-V-M-L-I-K-Q-G-L-V-V-E-K-C"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-S-E-F-F-A-K-I-L-I-I-L-I-R-L-Y-Q-I-L-I-S-P-L-F-A-P-C-C-R-F-Y-P-S-C-S-E-Y-A-I-I-A-V-R-K-H-G-L-S-K-G-S-R-L-A-L-I-R-L-F-K-C-H-P-F-H-P-G-G-Y-D-P-V-R"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-K-V-R-K-I-N-G-E-S-R-L-R-G-V-S-S-I-T-F-E-N-Q-F-V-V-N-D-I-R-I-I-E-G-E-R-G-I-F-I-A-M-P-S-R-K-T-S-K-G-N-F-R-D-I-A-H-P-I-N-S-E-T-R-Q-I-I-E-N-C-I-K-T-K-Y-Q-D-L-L-D-N-P-P-Q-E-E-D-F-S-Q-N-S-E-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-V-S-K-L-L-I-G-L-I-R-G-Y-Q-L-V-I-S-P-L-L-G-P-H-C-R-F-R-P-T-C-S-Q-Y-G-I-E-A-I-R-R-F-G-M-L-K-G-S-W-L-T-L-K-R-V-L-K-C-H-P-L-N-P-G-G-E-D-P-V-P-P-K-N-F-D-N-R-E-H"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-Y-C-T-F-L-K-R-E-A-E-G-Q-D-F-Q-F-Y-P-G-E-L-G-K-R-I-Y-D-N-I-S-K-E-A-W-T-Q-W-Q-T-K-Q-T-M-L-I-N-E-K-K-I-S-M-M-N-V-A-D-R-K-V-L-E-Q-E-M-I-N-F-L-F-E-G-Q-D-V-H-I-Q-G-Y-T-P-P-S-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-H-Y-Q-Q-S-D-A-E-G-L-D-F-V-P-Y-P-G-E-L-G-Q-R-I-F-A-H-I-G-K-T-A-W-Q-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-D-P-K-H-R-A-F-L-E-T-E-L-Q-K-F-L-F-E-R-N-A-D-K-P-D-G-Y-V-A-P-L-G-E-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-V-A-Y-H-W-Q-V-I-S-R-L-L-I-A-L-L-R-F-Y-K-L-F-I-S-P-L-L-G-P-R-C-R-F-A-P-S-C-S-E-Y-A-M-T-A-I-G-R-F-G-P-L-R-G-S-W-L-A-A-R-R-L-G-R-C-H-P-F-H-P-G-G-F-D-P-V-P-D-A-P-A-S-P-S-S-S-C-S-C-K-G-P-H-P"} +{"text": "### FUNCTION Acts in maintaining the cortical microtubules organization essential for anisotropic cell growth ### SEQUENCE -M-G-R-G-V-S-S-G-G-G-Q-S-S-L-G-Y-L-F-G-G-G-E-A-P-K-S-A-E-K-P-A-P-V-Q-K-P-A-P-S-S-S-A-E-K-L-K-E-I-P-A-G-I-Q-S-S-K-A-N-N-Y-M-R-A-E-G-Q-N-C-G-N-F-L-T-D-R-P-S-T-K-V-Q-A-A-P-G-G-G-S-S-L-D-Y-L-F-S-G-N-K-D-G-K"} +{"text": "### FUNCTION Acts in maintaining the cortical microtubules organization essential for anisotropic cell growth ### SEQUENCE -M-G-R-G-R-G-V-S-S-G-G-G-Q-S-S-L-G-Y-L-F-G-G-G-E-T-A-P-A-A-K-A-K-P-A-A-A-A-E-K-E-T-T-P-A-P-V-K-K-A-A-V-A-A-A-A-S-P-S-A-A-E-K-M-K-E-I-P-A-G-I-Q-S-T-Q-A-N-N-Y-F-R-A-Q-G-Q-N-C-G-N-F-L-T-D-R-P-S-T-K-V-H-A-A-P-G-G-G-S-S-L-G-Y-L-F-G-G-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-D-N-W-V-I-L-A-I-R-F-Y-Q-R-Y-I-S-P-L-L-G-R-H-C-R-F-Y-P-T-C-S-Q-Y-A-L-E-A-I-T-K-Y-G-L-L-R-G-G-L-L-A-T-R-R-L-L-H-C-H-P-W-D-A-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-P-L-A-A-L-S-Q-G-I-G-L-L-M-R-G-L-I-W-L-Y-R-L-F-L-S-P-L-L-G-Q-N-C-R-F-D-P-S-C-S-R-Y-A-L-E-A-I-T-R-H-G-P-F-W-G-L-W-L-A-V-R-R-I-S-R-C-H-P-W-G-G-M-G-Y-D-P-V-P-D-D-P-R-P-G-R-C-G-C-K-D-A-G-P-A-V-S-A-G-S-T-E-G-N-P-G-R-R-T-D-G-T-D-P-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-R-A-L-S-L-L-A-R-L-P-R-L-L-L-I-G-L-V-R-L-Y-Q-L-V-L-S-P-H-L-G-R-T-C-R-F-H-P-T-C-S-A-Y-A-I-Q-A-F-R-E-Y-G-A-L-K-G-L-V-L-T-V-H-R-L-L-R-C-H-P-W-G-G-H-G-Y-D-P-P-R-W-F-D-E-E-H-P-A-A-D-G-R-P-Q-A-A-E-E-Q"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-G-Q-H-E-V-T-A-R-L-S-E-L-T-N-T-F-I-E-R-H-H-S-S-S-R-Q-R-P-C-I-P-L-N-E-D-T-R-Y-M-L-D-S-P-C-V-E-H-V-D-E-E-A-G-V-F-Y-W-T-P-R-P-H-M-D-F-T-L-F-D-G-L-E-Q-G-L-E-V-A-I-H-P-S-I-T-A-F-Y-G-S-Y-W-S-D-G-L-W-C-S-S-P-F-G-E-I-S-L-I-Q-L-W-N-E-D-D-M-E-T-L-R-E-N-L-L-G-H-A-F-Q-K-S-K-R-R-Q-G-L-T-F-F-I-G-L-T-A-D-D-R-I-V-T-V-D-N-H-S-G-E-V-Y-L-E-E-A-G-R-P-P-Q-R-T-L-A-A-S-L-G-E-L-L-R-E-L-E-P-T-L-T-P-Y-T-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-F-C-K-K-Y-Q-Q-E-L-E-G-L-A-L-P-P-M-P-G-A-R-G-K-E-L-F-E-T-V-S-K-K-A-W-Q-E-W-L-Q-H-Q-T-M-L-I-N-E-K-R-L-N-L-M-D-P-D-A-R-T-Y-L-T-E-Q-M-E-K-F-L-N-N-E-N-F-D-A-A-E-G-F-V-P-K-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-K-L-K-N-N-L-L-E-K-T-L-E-L-S-E-L-F-K-I-Y-K-E-L-L-T-D-K-Q-K-Q-Y-F-E-L-Y-I-D-E-D-L-S-L-S-E-I-A-D-E-F-N-I-S-K-T-A-V-Y-D-S-I-S-K-T-S-K-L-L-F-S-L-E-K-K-L-H-L-K-Q-K-E-E-L-L-I-S-L-I-N-K-I-E-T-N-Q-I-D-E-K-Q-F-I-K-S-L-K-E-V-I-W-W-K-Y"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-H-S-N-V-K-K-V-T-D-K-D-V-I-K-P-V-G-V-P-F-V-V-Y-F-S-S-I-S-N-N-T-H-R-F-I-Q-K-L-E-I-E-N-L-R-I-P-Y-E-I-E-Q-S-I-S-V-D-R-D-Y-V-L-V-T-P-T-Y-S-G-G-G-E-Y-V-E-G-A-V-P-K-Q-V-I-K-F-L-N-N-K-Q-N-R-S-F-C-R-G-V-I-S-S-G-N-T-N-F-G-D-T-F-G-I-A-G-P-I-I-S-K-K-L-N-V-P-F-L-Y-Q-F-E-L-L-G-T-Q-H-D-V-S-Q-I-K-Q-I-L-F-K-F-W-E-D-G-N-N-E-R-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-V-L-I-A-L-L-R-F-Y-K-L-A-V-S-P-L-L-G-S-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-A-R-R-L-C-R-C-H-P-F-S-A-G-G-I-D-L-V-P-P-P-N-S-D-A-R-N-A-P-H-E-A-E-A-S-S-H-R-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-H-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-L-Y-E-S-V-S-K-E-A-W-Q-G-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-A-Q-D"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-L-H-T-W-I-R-T-L-G-A-L-L-L-L-A-S-V-A-H-A-Q-F-Q-F-F-E-H-M-F-G-G-G-R-Q-E-H-Q-Q-Q-A-A-Q-N-E-P-S-D-S-S-R-Y-Q-N-M-W-E-S-A-Q-C-D-K-Y-L-C-P-G-T-L-A-C-V-H-F-P-H-H-C-P-C-A-H-P-D-N-E-D-K-I-E-L-S-E-G-S-A-V-C-I-S-K-G-G-F-Q-P-G-E-A-A-R-K-I-E-L-A-R-K-G-V-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-P-I-G-L-G-M-R-G-L-I-R-L-Y-Q-L-L-L-S-P-V-L-P-A-S-C-R-F-T-P-S-C-S-S-Y-A-M-Q-A-I-E-A-H-G-P-V-G-G-T-W-L-G-L-K-R-I-C-R-C-H-P-W-N-D-G-G-Y-D-P-V-P-P-A-H-T-E-R-G-G-T-M-C-P-S-R-L-P-E"} +{"text": "### FUNCTION BREX systems provide immunity against bacteriophage Part of a type 1 BREX system which protects against dsDNA phage This system allows phage adsorption but prevents phage DNA replication, without degradation of the phage DNA Methylation of bacterial DNA by PglX guides self/non-self discrimination ### SEQUENCE -M-A-E-P-R-Y-K-A-D-I-G-G-G-S-L-K-L-P-E-S-R-I-I-A-G-L-L-L-E-G-V-T-E-D-Q-W-R-H-A-I-E-V-E-N-V-L-Q-R-R-S-P-G-T-A-K-R-Q-S-S-L-M-R-N-R-L-E-T-M-G-P-E-L-W-Q-M-V-R-D-G-S-T-Q-V-A-I-Q-A-V-F-A-A-A-I-K-H-S-T-L-L-G-D-F-L-D-L-V-V-R-D-Q-F-R-M-F-R-P-D-L-P-R-K-M-W-D-Q-Y-L-E-Q-C-R-N-R-D-P-L-M-P-V-W-Q-D-S-T-A-N-K-L-A-D-C-V-Y-R-I-L-V-E-V-G-Y-I-T-D-S-K-T-Y-R-L-K-S-V-R-I-S-G-E-V-M-S-Y-L-R-E-N-N-E-Q-Y-V-I-R-C-I-Q-V-S-I"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-T-A-T-T-Q-A-D-R-Y-I-S-F-S-G-I-D-C-D-G-N-A-K-I-V-L-E-R-V-V-A-L-V-A-L-P-E-Y-A-N-C-F-W-D-R-F-L-I-R-L-A-E-A-D-K-V-G-A-R-K-A-D-E-L-C-L-A-C-S-N-T-Y-Y-I-E-E-L-F-E-A-A-G-D-E-M-G-L-A-A-L-R-R-L-E-D-E-C-C"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-I-A-F-I-R-L-Y-Q-Y-C-L-S-P-F-L-G-P-S-C-R-F-S-P-S-C-S-H-Y-A-C-E-A-L-A-R-H-G-A-T-R-G-L-V-L-S-V-W-R-I-M-R-C-N-P-W-S-R-G-G-Y-D-P-V-P-A-E-P-F-R"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-G-R-T-V-N-C-I-K-L-G-R-E-L-E-G-L-D-F-P-P-Y-P-G-E-L-G-K-R-I-F-E-N-V-S-K-E-A-W-A-G-W-I-R-H-Q-T-M-L-V-N-E-Y-H-L-N-L-S-D-I-K-A-R-K-Y-L-A-E-Q-L-D-A-Y-F-F-G-S-G-A-E-Q-P-R-G-Y-V-P-L-A-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-S-C-G-G-K-H-T-G-K-G-A-P-K-P-Y-S-R-N-F-T-D-P-W-R-K-T-P-G-R-L-F-G-T-A-L-I-R-F-Y-Q-I-T-L-S-S-L-I-G-N-S-C-R-H-L-P-T-C-S-E-Y-A-Y-E-A-I-A-R-H-G-L-W-R-G-G-W-M-G-F-F-R-V-V-R-C-G-P-F-G-T-H-G-F-D-P-V-P-R-E-L-S-P-D-L-K-W-Y-M-P-W-R-Y-W-R-C-S-A-S-R-I-G-K"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-R-L-F-E-E-S-N-E-D-V-V-E-I-Q-R-A-N-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-A-T-G-Y-I-N-H-L-L-Q-L-I-G-P-S-I-S-Q-Q-Q-A-Y-Y-I-I-D-G-L-L-D-K-M-L-I-N-E-R-E-A-K-M-I-H-A-V-I-D-R-E-T-L-S-M-D-M-V-S-R-D-I-I-R-A-N-I-L-K-R-L-L-P-V-I-N-Y-Y"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity ### SEQUENCE -M-L-S-F-S-Q-N-R-S-H-S-L-E-Q-S-L-K-E-G-Y-S-Q-M-A-D-L-N-L-S-L-A-N-E-A-F-P-I-E-C-E-A-C-D-C-N-E-T-Y-L-S-S-N-S-T-N-E"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-V-P-D-K-N-A-T-S-E-D-S-E-E-A"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-R-N-E-I-F-E-K-I-M-R-L-E-M-N-V-N-Q-L-S-K-E-T-S-E-L-K-A-L-A-V-E-L-V-E-E-N-V-A-L-Q-L-E-N-D-N-L-K-K-V-L-G-N-D-E-P-T-T-I-D-T-A-N-S-K-P-A-K-A-V-K-K-P-L-P-S-K-D-N-L-A-I-L-Y-G-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-F-C-L-E-V-L-S-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Accessory element involved in the expression of sarA and several virulence factors Modulates SarA production and/or function in a strain-dependent manner Affects the transcription of the accessory gene regulator ### SEQUENCE -M-K-Y-L-I-L-S-L-V-A-N-L-L-V-F-G-V-L-S-A-I-G-L-N-I-N-I-L-A-A-M-M-M-I-L-V-I-P-I-T-I-S-G-I-L-F-F-K-T-N-L-D-K-T-Y-I-F-F-N-I-L-F-I-D-F-Y-Y-Y-I-Y-N-V-H-L-M-A-L-P-R-F-N-S-Y-I-K-A-E-M-M-E-L-E-D-I-D-V-L-I-T-S-K-D-F-G-F-D-E-I-L-F-F-T-L-Y-L-L-L-I-L-I-I-L-Y-Y-L-K-K-Q-V-K-T-K-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-I-E-L-R-K-I-A-I-L-P-I-R-F-Y-Q-R-F-I-S-P-L-F-P-P-S-C-R-F-V-P-T-C-S-A-Y-A-A-E-A-V-L-R-H-G-I-I-K-G-G-F-L-A-L-R-R-I-L-R-C-N-P-L-C-A-G-G-Y-D-P-V-P-E-S-R-H-Q-D-A-K-R-V-R-S-C"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-F-K-T-I-N-K-S-I-T-S-I-L-L-F-M-I-S-F-Y-Q-K-W-F-S-P-F-F-G-P-R-C-R-F-I-P-S-C-S-S-Y-G-Y-E-A-I-T-R-H-G-P-W-K-G-G-W-L-T-L-R-R-L-S-R-C-H-P-L-T-P-C-G-C-D-P-V-P-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-P-F-K-W-L-I-I-L-P-V-R-F-Y-Q-L-F-I-S-P-I-L-G-P-R-C-R-F-Y-P-T-C-S-H-Y-T-I-E-A-V-Q-Q-H-G-V-F-C-G-L-W-L-A-I-K-R-I-A-K-C-H-P-G-N-P-G-G-V-D-P-V-P-S-C-G-C-H-S-D-K-E-T-T-P-K-E-K-S-D-N-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-M-V-N-C-V-K-M-E-Q-E-L-E-G-L-D-F-P-P-F-P-G-D-L-G-Q-K-I-Y-E-N-V-S-K-E-A-W-K-Q-W-L-A-Q-Q-T-I-L-I-N-E-Y-R-L-S-S-L-D-P-K-A-Q-N-F-L-K-E-E-M-Q-K-F-L-F-G-G-E-D-L-E-M-P-E-E-F-Q-A-I-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-L-L-L-L-A-L-I-Q-F-Y-R-R-W-I-S-P-L-T-P-A-S-C-R-F-Y-P-T-C-S-Q-Y-G-L-E-A-I-D-R-F-G-P-L-K-G-S-W-L-T-L-C-R-I-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P-P-L-P-S-C-S-C-G-K-S-P-C-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-M-P-A-V-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-E-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-T-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-E-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-S-A-I-H-T-F-Y-T-T-Q-F-A-G-D-I-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-Q-L-V-Y-F-S-S-S-S-E-N-T-Q-R-F-I-E-R-L-G-L-P-A-V-R-I-P-L-N-E-R-K-Q-I-Q-V-D-E-P-Y-I-L-I-V-P-S-Y-G-G-G-G-T-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-L-L-R-G-V-I-A-S-G-N-R-N-F-G-E-A-Y-G-R-A-G-D-V-I-A-R-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-S-D-I-E-N-V-R-K-G-V-T-E-F-W-Q-R-Q-P-Q-N-A"} +{"text": "### FUNCTION This protein is involved in the replication of the phage DNA ### SEQUENCE -M-N-N-Y-Q-L-T-I-K-E-V-L-Y-I-I-K-T-S-R-N-Y-G-K-K-S-S-A-K-L-H-T-I-T-V-K-E-L-I-T-D-V-L-N-L-K-Y-T-I-D-I-I-L-T-E-L-N-S-V-D-R-V-K-M-N-N-Y-M-L-A-I-L-E-A-V-E-Y-I-E-D-T-Q-E-I-I-S-S-L-S-N-K-D-T-S-A-K-G-L-S-K-L-P-K-P-R-L-V-E-I-F-L-R-L-E-N-L-M-Y-R-I-E-D-I-L-E-V-T-N-N-D"} +{"text": "### FUNCTION Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance ### SEQUENCE -M-T-T-I-Y-K-E-L-V-A-H-F-G-T-Q-D-E-T-A-A-K-L-G-V-D-Q-S-T-V-S-G-W-V-R-G-K-H-G-M-S-P-V-V-A-K-R-A-Q-V-L-T-D-G-K-F-K-K-E-D-L-C-P-A-F-P-W-E-V-L-S-A-V-A"} +{"text": "### FUNCTION No function has yet been ascribed to K protein ### SEQUENCE -M-K-H-V-N-T-L-L-M-Q-E-L-R-L-L-I-C-E-L-K-R-L-K-L-S-A-V-S-D-P-D-F-S-Q-E-K-I-H-A-E-L-D-S-L-L-C-K-L-S-R-H-F-D"} +{"text": "### FUNCTION Seems to be involved in escape from killing mediated by the bacterial type III toxin-antitoxin module AbiQ toxin protein upon infection of Llactis subsp lactis strain IL1403 A single variant independently isolated from 5 different phage confers on the virus the ability to partially escape killing ### SEQUENCE -M-I-N-L-Q-N-K-K-L-D-I-K-E-F-L-Q-E-L-G-F-T-V-S-L-D-Y-E-R-E-P-M-G-V-M-F-A-E-I-H-P-I-V-S-Q-V-S-N-N-S-A-I-Y-Q-S-F-R-T-L-E-I-E-L-M-V-I-C-T-E-E-T-E-N-S-L-Y-R-A-V-Q-L-L-S-D-E-H-Y-I-Y-A-N-T-I-T-D-N-T-N-I-I-K-L-R-G-N-Y-Y-D"} +{"text": "### FUNCTION Needed for optimal phage development ### SEQUENCE -M-A-T-L-Q-D-V-H-L-R-V-N-D-R-V-T-P-V-Y-F-T-A-R-S-F-L-L-V-S-P-K-R-A-G-Q-A-T-F-L-A-R-E-E-G-T-D-N-P-V-V-T-C-H-V-S-D-F-Y-K-D-G-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-I-L-I-A-L-V-R-F-Y-Q-T-G-I-S-P-F-L-P-P-S-C-R-Y-Y-P-T-C-S-S-Y-M-I-Q-A-I-Q-K-H-G-A-I-K-G-L-A-M-G-I-G-R-I-L-R-C-H-P-F-I-K-G-G-Y-D-P-V-P-D-H-F-T-V-F-R-N-K-S-V-D-H"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-L-A-Q-N-A-R-M-N-S-L-F-E-F-Y-G-A-L-L-T-A-K-Q-H-S-Y-L-S-L-Y-Y-G-D-D-F-S-L-G-E-I-A-E-E-Y-Q-V-S-R-Q-A-V-Y-D-N-I-R-R-T-E-K-I-L-E-G-Y-E-A-K-L-H-L-F-Q-N-Y-E-Q-Q-N-A-S-A-D-A-L-Q-K-Y-I-Q-A-Q-Y-P-N-D-Q-Q-L-A-K-L-L-A-D-L-L-N-L-T-E-Q"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-S-K-T-D-L-Y-E-Q-L-L-T-I-E-Q-Q-A-K-L-T-F-D-G-I-T-E-M-K-A-V-L-S-K-V-L-E-E-N-A-E-L-E-I-E-N-K-H-L-R-E-H-L-Q-E-L-Q-Q-T-T-E-E-T-D-T-K-D-L-S-Q-G-L-S-K-S-K-Q-N-L-Q-N-L-Y-E-E-G-F-H-I-C-P-Y-F-Y-G-S-R-R-E-N-D-E-P-C-A-F-C-N-D-V-I-Y-G-E-R-T-A-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-E-T-V-L-I-A-L-L-R-F-Y-K-V-A-V-S-P-M-L-G-N-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-V-R-R-V-C-R-C-H-P-F-S-A-G-G-I-D-L-V-P-P-P-N-S-D-T-R-A-R-G-E-A-D-A-R-S-H-R-L"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-Q-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-I-Y-E-S-V-S-K-E-A-W-Q-G-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-D-G-A-D-Q-A-S-G-Y-V-P-P-T-E-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-I-L-I-K-I-I-G-I-Y-Q-R-Y-L-S-P-L-T-G-P-T-C-R-F-Y-P-S-C-S-T-Y-A-K-E-S-L-M-R-H-G-L-L-K-G-L-W-Y-S-A-V-R-I-M-K-C-H-P-Y-H-P-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-R-K-F-L-I-V-L-I-I-A-Y-Q-R-Y-I-S-P-F-T-A-P-S-C-R-F-Y-P-S-C-S-E-Y-A-R-Q-S-L-I-K-Y-G-L-I-K-G-V-V-K-T-C-G-R-L-C-R-C-H-P-F-H-P-G-G-Y-D-P-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-I-I-L-L-L-I-R-F-Y-Q-K-F-V-S-P-I-L-G-S-N-C-R-F-Y-P-S-C-S-Q-Y-T-Y-E-A-I-E-R-Y-G-V-I-Y-G-S-Y-L-G-I-K-R-I-L-R-C-H-P-F-T-P-G-G-Y-D-P-V-P-E-K-K-L-R-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-H-E-S-N-T-L-Y-G-G-P-M-T-K-L-R-Q-A-I-N-Q-V-L-A-A-V-L-L-A-G-I-G-F-Y-R-R-F-I-S-P-M-I-G-P-R-C-R-F-T-P-T-C-S-A-Y-G-L-E-A-I-Q-K-H-G-P-W-K-G-G-W-L-T-V-K-R-L-L-R-C-H-P-F-T-P-C-G-C-D-P-V-P-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-I-W-K-I-I-N-A-I-P-I-V-L-I-R-L-Y-R-T-F-L-S-P-L-L-G-P-S-C-K-Y-V-P-T-C-S-S-Y-A-L-E-A-F-E-R-H-N-F-F-Y-A-L-W-L-T-I-W-R-I-L-R-C-N-P-F-S-K-G-G-Y-D-P-V-P-P-L-Q-G-T-Q-Q-S-S-S-H-H-Q-E-S-S-H-H-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-H-E-S-P-I-L-S-N-G-D-Q-P-N-R-W-A-G-L-N-R-R-V-A-A-L-L-L-A-L-I-G-F-Y-R-T-F-I-S-P-L-L-G-P-R-C-R-F-T-P-T-C-S-A-Y-G-L-E-A-I-Q-R-H-G-P-W-R-G-G-W-L-T-L-K-R-V-L-R-C-H-P-F-T-P-C-G-C-D-P-V-P-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-I-W-K-V-V-N-K-A-P-L-A-L-I-K-F-Y-R-A-I-L-S-P-M-F-P-P-S-C-R-F-Y-P-T-C-S-A-Y-A-L-E-A-F-E-T-H-N-F-F-K-A-S-W-L-S-L-W-R-I-L-R-C-N-P-F-S-K-G-G-F-D-P-V-P-P-H-D-G-V-P-G-K-K-E-D"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-H-Y-Q-Q-S-D-A-E-G-L-D-F-V-P-Y-P-G-E-L-G-Q-R-I-F-V-Q-I-G-K-T-A-W-Q-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-D-P-K-H-R-A-F-L-E-A-E-L-Q-K-F-L-F-E-R-N-A-D-K-P-E-G-Y-V-A-P-V-R-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-V-A-Y-H-W-Q-V-I-S-R-L-L-I-A-L-L-R-V-Y-K-L-V-I-S-P-L-L-G-P-R-C-R-F-A-P-S-C-S-D-Y-A-M-T-A-I-G-R-F-G-P-L-R-G-S-W-L-A-A-R-R-L-G-R-C-H-P-F-H-P-G-G-F-D-P-V-P-D-A-P-A-S-P-S-P-S-S-S-C-S-C-K-G-P-H-P"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-S-V-V-L-Q-L-T-Q-L-H-Q-R-F-N-D-K-T-L-K-N-T-Q-K-H-P-L-M-V-H-D-E-Q-W-P-S-P-C-E-I-G-N-V-D-Q-Q-G-N-I-Q-W-Q-A-V-L-Q-Q-P-A-G-S-L-N-D-L-A-K-A-L-D-V-T-F-P-S-G-L-N-A-L-Y-G-H-M-Y-G-G-N-I-Q-A-S-I-D-G-H-Q-V-E-L-L-Q-V-W-N-S-D-D-F-D-L-L-Q-Q-N-I-T-G-H-V-L-M-K-R-K-L-K-Q-P-E-T-V-F-I-G-L-T-A-Q-D-D-L-L-V-C-V-L-L-H-S-G-E-V-C-L-E-Y-V-G-K-K-T-H-H-V-L-A-A-N-I-E-E-F-L-Q-A-L-E-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-L-L-K-P-L-V-A-L-P-T-Y-C-L-V-L-F-I-R-G-Y-Q-K-W-I-S-P-L-L-G-P-H-C-R-F-N-P-T-C-S-S-Y-A-I-Q-A-I-N-L-H-G-S-V-K-G-S-W-L-A-V-K-R-I-L-K-C-H-P-L-H-S-G-G-N-D-P-V-P-E-K-L-T-H-I-N-H-Q-H-E-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-Q-K-L-Q-K-E-A-E-G-L-G-F-Q-L-Y-P-G-E-I-G-E-K-I-F-N-N-I-S-K-E-A-W-A-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-H-L-N-M-M-D-P-E-H-R-S-F-L-E-Q-Q-M-V-G-F-L-F-E-N-K-E-V-E-I-E-G-Y-K-P-P-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-P-L-A-Q-V-L-A-L-P-V-R-A-Y-R-L-L-L-S-P-W-V-G-H-G-C-R-Y-Q-P-T-C-S-V-Y-A-L-D-A-L-E-R-H-G-A-L-K-G-G-W-L-A-A-R-R-I-L-S-C-H-P-W-G-G-S-G-Y-D-P-V-P-G-A-D-P-E-H-D-R-R-P-R-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-I-L-L-S-L-I-I-F-Y-R-Y-A-L-S-P-F-M-G-N-H-C-R-Y-Y-P-S-C-S-V-Y-T-Q-E-A-I-Q-R-Y-G-G-F-R-G-G-W-L-G-L-R-R-L-L-R-C-H-P-F-C-P-G-G-I-D-Q-V-P-E-I-A-K-W-R-S-K-S"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-H-C-V-K-L-D-H-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-K-R-L-Y-E-Q-V-S-K-E-A-W-Q-M-W-M-K-H-Q-T-I-L-I-N-E-Y-R-L-T-L-V-D-P-K-A-R-Q-F-L-E-Q-E-M-E-K-F-F-F-G-E-G-S-T-P-P-Q-E-Y-T-P-P-E-Q"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-H-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-L-Y-E-S-V-S-K-Q-A-W-Q-D-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-A-Q-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-V-L-I-A-L-L-R-F-Y-K-L-A-V-S-P-L-L-G-S-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-A-R-R-L-C-R-C-H-P-F-S-A-G-G-V-D-L-V-P-P-P-N-S-D-A-R-N-A-P-H-E-A-E-A-S-S-H-R-L"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-D-L-F-D-A-F-D-D-F-S-Q-N-L-L-V-G-L-S-E-I-E-T-M-K-K-Q-I-Q-K-L-L-E-E-N-T-V-L-R-I-E-N-G-K-L-R-E-R-L-S-V-I-E-A-E-T-E-T-A-V-K-N-S-K-Q-G-R-E-L-L-E-G-I-Y-N-D-G-F-H-I-C-N-T-F-Y-G-Q-R-R-E-N-D-E-E-C-A-F-C-I-E-L-L-Y-R-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-L-A-L-V-P-I-R-F-Y-R-Y-A-I-S-P-L-M-A-S-H-C-R-F-Y-P-S-C-S-C-Y-A-Y-E-A-I-E-N-H-G-L-L-R-G-G-W-L-T-F-R-R-L-G-R-C-H-P-W-N-P-G-G-Y-D-P-V-P-P-I-P-T-S-R-S-S-S-M-A-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-M-C-R-K-Y-K-E-Q-L-E-G-L-E-R-P-P-Y-P-G-A-K-G-Q-D-I-F-E-H-V-S-A-K-A-W-A-D-W-Q-K-H-Q-T-L-L-I-N-E-K-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-G-E-M-D-K-Y-F-S-G-E-E-Y-A-Q-A-E-G-Y-V-P-P-A-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-S-R-I-S-S-F-F-R-G-L-V-H-L-Y-R-W-A-I-S-P-F-L-G-A-P-C-R-F-F-P-T-C-S-E-Y-A-L-V-A-L-K-K-H-P-L-R-K-S-L-F-L-I-A-K-R-L-L-K-C-G-P-W-C-I-G-G-I-D-L-V-P-R-T-S-V-E-E-Y-L-S-S-P-T-P-L-A-E-S-P-D-D-R-T-V-P-H-T-Q-E-T-S"} +{"text": "### FUNCTION Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation ### SEQUENCE -M-A-T-V-R-P-F-D-K-M-P-M-L-N-A-A-A-L-L-L-V-G-T-E-E-S-H-R-E-Q-L-A-S-A-M-L-K-E-P-K-T-F-E-V-K-I-H-M-A-Q-S-L-P-L-P-Y-E-R-E-H-L-R-P-R-F-D-M-V-V-F-L-I-N-L-H-S-Q-L-S-L-S-T-I-L-A-S-L-T-Q-L-D-V-N-F-F-L-G-K-V-C-F-V-A-T-G-G-G-Q-V-K-H-C-M-V-D-I-A-T-V-K-K-L-A-D-T-H-L-S-T-L-L-F-S-E-F-A-S-E-D-D-V-T-C-T-A-Q-R-L-L-Q-M-L-K-I-C-A-G-L-V-P-G-I-S-A-L-Y-L-G-S-F-M-S-S-T-L-Q-T-D-Q-F"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-W-L-I-K-G-Y-R-M-F-I-S-P-L-F-P-P-T-C-R-F-Q-P-T-C-S-M-Y-A-L-E-A-I-E-R-F-G-V-F-R-G-G-W-M-G-I-R-R-I-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P-E-V-G-E-H-C-C-H-H-D-S-G-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-L-A-Q-K-C-L-V-G-A-I-R-V-Y-Q-L-A-L-S-P-W-L-G-R-Q-C-R-Y-L-P-T-C-S-E-Y-G-K-E-A-I-E-K-H-G-A-L-K-G-S-W-L-A-A-K-R-I-G-R-C-R-P-G-C-S-H-G-Y-D-P-V-P-P-V-D-P-R-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-M-V-N-C-V-K-L-G-R-E-A-E-G-L-A-F-Q-P-V-P-G-D-L-G-K-K-I-F-E-N-V-S-K-E-A-W-A-G-W-Q-R-H-Q-T-M-L-I-N-E-N-R-L-N-L-A-D-P-Q-A-R-S-Y-L-M-E-Q-M-E-R-Y-F-F-G-G-G-N-V-D-A-A-A-G-Y-V-P-P-T-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-I-P-S-E-V-R-C-S-R-L-C-P-A-C-T-N-A-A-L-R-L-P-R-N-A-G-R-A-L-I-W-I-Y-R-H-T-L-S-P-L-V-G-F-N-C-R-H-L-P-T-C-S-A-Y-G-D-E-A-I-A-R-F-G-L-W-G-G-G-W-M-T-L-A-R-I-L-R-C-R-P-W-G-T-S-G-I-D-N-V-P-V-A-K-P-S-G-A-T-W-Y-R-P-W-R-Y-G-R-W-R-G-V-N-A-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-D-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-A-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-R-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Component of the NCC cation-efflux system that confers resistance to nickel, cobalt and cadmium May be involved in the regulation of NCC ### SEQUENCE -M-E-N-I-D-E-W-L-V-Q-A-K-K-V-T-Y-E-A-S-R-E-P-G-L-G-R-I-Q-Q-R-L-S-R-E-P-S-Q-M-V-L-T-A-R-H-D-I-L-R-A-V-C-C-A-A-L-A-S-L-V-A-F-T-A-I-D-R-I-A-V-G-L-Y-Q-K-Q-Q-P-T-W-V-A-A-P-S-A-A-S-P-F-G-L-L-I-G-K"} +{"text": "### FUNCTION The cotJ operon proteins affect spore coat composition They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat ### SEQUENCE -M-K-D-M-Q-P-F-T-P-V-K-S-Y-T-P-F-H-S-R-F-D-P-C-P-P-I-G-K-K-Y-Y-R-T-P-P-N-L-Y-M-T-F-Q-P-E-H-M-E-Q-F-S-P-M-E-A-L-R-K-G-T-L-W-K-D-L-Y-D-F-Y-E-N-P-Y-R-G-G-D-A-H-G-K-K-G"} +{"text": "### FUNCTION Not known ### SEQUENCE -M-V-H-N-D-L-D-F-I-F-Y-N-N-L-K-H-S-S-G-A-I-E-H-L-G-D-N-L-T-G-D-G-D-X-D-D-E-E-I-I-I-D-L-S-L-I-P-Q-N-I-S-R-I-N-F-T-V-T-I-H-E-A-G-E-R-S-Q-N-F-G-Q-V-S-N-A-Y-V-R-V-V-N-S-D-N-S-Q-E-L-L-K-Y-D-L-G-E-D-F-S-I-E-T-A-I-V-V-A-E-I-Y-R-H-N-G-E-W-K-F-N-A-I-G-S-G-F-Q-G-G-L-A-A-L-C-R-N-F-G-L-N-V"} +{"text": "### FUNCTION Not known ### SEQUENCE -M-G-I-V-L-K-K-G-Q-K-V-D-L-T-K-G-N-A-S-L-K-K-V-I-I-G-L-G-W-D-V-N-K-Y-D-G-G-H-D-F-D-L-D-A-V-A-F-C-C-G-E-D-G-K-V-H-N-E-A-D-M-I-F-Y-N-N-L-K-H-S-S-G-A-V-E-H-L-G-D-N-L-T-G-D-G-D-G-D-D-E-Q-I-L-I-D-L-S-S-I-P-Q-H-I-N-K-I-D-F-T-V-T-I-H-E-A-E-E-R-K-Q-N-F-G-Q-V-S-N-S-Y-V-R-V-V-N-S-D-T-K-E-E-L-I-K-Y-D-L-G-E-D-F-S-I-E-T-A-I-V-V-A-E-L-Y-R-N-G-S-E-W-K-F-N-A-I-G-S-G-F-E-G-G-L-A-A-L-C-K-N-F-G-L-N-V"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-L-V-T-S-S-R-K-P-S-A-R-T-R-T-L-C-K-L-L-S-R-F-I-A-G-R-C-M-T-R-G-K-M-G-M-Q-E-L-L-E-F-A-E-G-G-P-L-I-V-I-G-E-Y-H-G-N-P-G-E-L-S-F-Y-D-E-A-G-E-L-L-F-S-L-R-F-T-D-W-Y-S-K-E-L-D-S-Y-W-F-S-G-I-E-P-K-L-A-G-Q-G-E-I-A-E-A-F-K-V-F-F-H-F-Q-R-V-E-N-D-K-I-D-Q-L-P-P-S-S-T-L-I-V-V-G-E-N-D-I-D-F-M-G-S-G-K-S-L-F-K-L-N-L-R-G-F-K-K-Y"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-T-K-I-N-K-A-I-A-L-V-F-V-S-L-I-S-F-Y-Q-K-W-I-S-P-L-F-G-P-S-C-R-F-I-P-S-C-S-A-Y-G-I-E-A-V-N-K-H-G-P-W-R-G-G-W-L-T-L-K-R-L-S-K-C-H-P-L-T-P-C-G-C-D-P-V-P-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-L-A-L-L-R-I-Y-K-I-A-L-S-P-Y-L-G-S-R-C-R-F-W-P-T-C-S-D-Y-A-R-E-A-V-I-Q-H-G-A-A-R-G-S-W-M-A-A-C-R-L-C-R-C-H-P-F-T-Q-G-G-Y-D-P-V-P-G-V-E-T-E-T-A-Q-T-G-K-F-A-H-P-A-A-G-H-G-P-V-T-V-R-L-P-R-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-Q-C-I-K-L-N-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-K-I-W-Q-S-V-S-K-E-A-W-A-G-W-L-K-H-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-A-R-A-R-Q-Y-L-L-K-Q-T-E-K-Y-F-F-G-E-G-A-D-E-A-A-G-Y-V-P-P-Q-A"} +{"text": "### FUNCTION May have a possible regulatory function on the expression of the other AFA-III genes ### SEQUENCE -M-K-I-N-K-L-T-L-N-E-R-K-N-D-I-L-S-Y-F-S-E-I-N-T-P-F-R-T-S-E-V-A-E-H-L-G-V-S-A-Y-Q-A-R-H-Y-L-Q-C-L-E-K-E-G-K-I-K-R-S-P-V-R-R-G-A-S-T-L-W-E-I-S-A-V-T-E-P-S-V-K-T-D-R-I-A-D"} +{"text": "### FUNCTION May have a possible regulatory function on the expression of the other daa genes ### SEQUENCE -M-K-I-N-K-L-T-L-N-E-R-K-N-D-I-L-S-Y-F-G-E-I-N-A-P-C-R-T-S-E-V-A-E-H-L-G-V-S-A-Y-Q-A-R-H-Y-L-Q-C-L-E-K-E-G-K-I-K-R-S-P-V-R-R-G-A-S-T-L-W-E-I-S-S-I-P-P"} +{"text": "### FUNCTION Regulates the transcription of genes involved in the biosynthesis of F1845 fimbrial adhesin ### SEQUENCE -M-S-G-Q-V-P-E-Y-Q-F-W-L-L-A-E-I-S-P-V-H-S-E-K-V-I-N-A-L-R-D-Y-L-V-M-G-Y-N-R-M-E-A-C-G-R-H-G-V-S-P-G-Y-F-S-G-A-L-K-R-F-Q-R-V-S-Q-T-V-Y-R-L-V-P-F-Y-F-P-E-A-G-H-E-V-H-R-G-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Y-L-L-I-A-L-V-R-G-Y-Q-Y-A-I-S-P-F-L-G-R-S-C-R-Y-V-P-T-C-S-E-Y-M-V-D-A-V-Q-K-H-G-A-F-R-G-G-W-L-G-V-K-R-V-C-R-C-H-P-W-H-P-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION May be involved in the regulation of muramidase-2 export ### SEQUENCE -M-Q-L-L-R-E-V-D-F-K-Q-T-R-C-N-A-R-D-V-L-K-N-F-R-R-L-E-R-M-A-G-R-S-L-I-D-I-K-S-P-I-I-T-D-M-P-K-A-P-K-H-G-N-K-A-E-D-A-I-I-Q-M-M-D-I-E-A-E-R-D-A-I-L-A-A-L-M-A-L-S-L-I-S-R-Q-I-L-Y-Y-S-F-C-V-P-D-S-F-S-N-Y-R-I-S-R-E-V-G-Y-S-E-R-S-I-Q-R-M-K-S-E-A-L-I-E-F-A-E-A-Y-K-H-G-R-I-I-A-Y-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-I-K-L-G-R-E-A-E-G-L-D-F-P-P-Y-P-G-P-L-G-Q-R-I-F-E-H-V-S-K-E-A-W-Q-Q-W-I-K-M-Q-T-M-I-I-N-E-N-R-L-N-L-V-D-A-K-H-R-K-Y-L-A-E-Q-V-E-K-H-F-F-G-E-G-A-D-Q-I-Q-G-Y-V-P-P-A-A"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-P-Q-D-C-A-C-R-K-T-D-R-Y-V-S-F-Q-D-I-D-C-T-G-N-A-R-R-L-M-E-H-L-D-R-Q-L-S-I-P-G-R-S-T-A-F-W-E-Y-F-A-K-K-R-A-G-S-A-A-A-K-P-D-D-L-F-L-I-H-S-N-I-N-Q-F-R-E-F-F-E-Q-W-N-D-S-D-A-L-S-L-L-L-Q-I-E-E-E-C-C"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-R-D-R-P-T-L-L-A-R-V-L-I-L-P-I-R-G-Y-Q-R-W-I-S-P-L-F-P-P-V-C-R-F-Y-P-S-C-S-S-Y-A-V-E-A-L-R-V-H-G-A-G-R-G-L-W-L-T-I-R-R-L-G-K-C-H-P-F-H-P-G-G-L-D-P-V-P-P-R-R-N-E-S-G-T-E-I-S-D-A-R-P-G-S-D-G-E-A-S-P-G-A-P-G-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-K-N-N-S-T-P-Q-K-L-V-I-T-G-I-K-G-Y-Q-R-F-I-S-P-L-L-G-S-N-C-R-F-T-P-S-C-S-A-Y-A-T-E-A-I-N-R-F-G-V-I-K-G-G-W-L-A-S-K-R-I-L-R-C-H-P-L-N-D-G-G-E-D-P-V-P-P-I-K-K-S-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-Q-N-L-N-K-E-A-E-G-L-G-F-Q-L-Y-P-G-E-I-G-K-R-I-F-D-N-I-S-K-E-A-W-T-I-W-Q-K-K-Q-T-M-L-I-N-E-K-K-M-N-M-M-N-V-D-D-R-A-F-L-E-A-A-M-V-A-Y-L-F-E-G-K-E-P-E-I-E-G-Y-V-P-P-S-K"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-T-N-N-E-N-S-T-N-L-L-K-V-N-K-A-R-L-K-W-A-C-R-R-G-M-L-E-L-D-V-L-F-I-P-F-V-D-E-A-Y-D-E-L-S-T-K-D-Q-F-T-F-E-R-L-L-T-G-Q-D-P-E-L-F-A-W-F-M-G-H-E-V-C-E-D-T-E-L-N-A-M-V-Q-L-I-L-K-R-V-K-V"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-T-S-T-N-K-T-L-T-Q-A-I-L-N-F-S-K-S-Y-S-Q-Q-H-V-E-Q-F-G-H-L-P-T-V-E-H-D-E-Q-W-P-S-P-C-D-L-G-S-H-D-T-S-H-H-Y-W-Q-A-V-A-M-E-S-V-Q-L-A-D-N-K-E-E-A-L-S-F-E-N-V-E-S-A-L-N-I-E-L-H-P-D-I-K-I-Y-F-T-T-I-F-S-G-D-I-E-A-Q-S-D-D-G-E-L-S-L-L-F-A-W-N-K-D-D-F-E-R-L-Q-E-N-I-I-G-H-I-L-M-K-Q-K-L-K-Q-V-E-T-V-F-F-A-V-T-D-E-E-D-M-I-I-S-V-D-N-S-S-G-E-V-W-V-E-Q-V-G-C-K-P-H-K-K-L-S-D-S-L-A-E-F-I-S-Q-L-T-H-K-N-V-V-S-E-K-S"} +{"text": "### FUNCTION This protein is involved in the attenuation mechanism for the control of the expression of the his operon structural genes ### SEQUENCE -M-N-S-V-Q-F-K-N-H-H-H-H-H-H-P-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-L-A-L-V-P-I-Q-F-Y-R-Y-A-M-S-P-L-M-A-S-H-C-R-F-Y-P-S-C-S-C-Y-A-Y-E-A-I-E-N-H-G-L-L-R-G-G-W-L-S-I-R-R-L-G-R-C-H-P-W-N-P-G-G-Y-D-P-V-P-A-V-P-T-S-R-S-S-S-M-A-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-M-C-R-K-Y-K-E-E-L-P-G-L-E-R-A-P-Y-P-G-A-K-G-E-D-I-F-N-H-V-S-Q-K-A-W-A-D-W-Q-K-H-Q-T-L-L-I-N-E-R-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-T-E-M-D-K-F-L-S-G-E-E-Y-A-Q-A-E-G-Y-V-P-P-E-K"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-V-E-D-V-E-L-N-R-L-Y-W-H-S-R-R-G-M-L-E-L-D-V-L-L-V-P-F-V-R-E-V-Y-P-H-L-N-D-V-D-R-D-L-Y-R-R-L-L-T-C-E-D-Q-D-M-F-G-W-F-M-Q-R-A-E-S-E-D-A-E-L-Q-R-M-V-R-M-I-L-D-R-V-Q-P-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-N-I-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-P-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-Q-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-K-Q-I-N-N-L-I-T-E-R-T-H-P-C-H-K-P-M-R-H-T-S-H"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-S-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-H-L-E-H-E-T-V-A-K-N-P-S-K-Q-R-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-A-G-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-A-E-K-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-K-I-I-Y-C-V-F-L-K-K-Y-A-E-G-L-D-A-P-C-Y-P-G-A-L-G-K-Y-I-Y-E-H-I-S-N-I-A-W-M-Q-W-Q-D-K-Q-T-I-L-I-N-E-N-K-L-N-M-M-N-I-A-D-R-T-I-L-E-K-E-M-K-I-F-L-F-G-K-N-F-S-I-K-N-N"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-R-S-D-I-F-E-K-L-A-N-L-E-A-N-I-N-Q-I-N-S-D-M-G-N-L-K-K-L-T-V-E-V-I-E-E-N-V-A-L-Q-I-E-N-E-N-L-K-T-L-I-D-K-E-E-K-S-K-A-V-E-N-G-K-K-L-P-K-K-Q-P-L-R-S-K-D-N-L-A-M-L-Y-K-E-G-F-H-I-C-N-G-E-L-F-G-K-H-R-K-G-D-D-C-L-F-C-L-E-V-L-S-E"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-S-F-V-V-H-D-L-R-V-I-E-G-N-T-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-E-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-E-E-T-D-E-V-I-P-D-R-N-A-Q-S-S-D-D-S-E-E-A"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-K-L-F-E-D-T-N-E-D-V-V-E-I-R-R-T-N-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-E-T-G-Y-I-N-H-L-L-Q-L-V-G-P-S-I-S-Q-Q-Q-A-Y-Y-I-V-D-G-L-L-D-K-S-Y-I-N-E-R-E-A-K-M-I-Y-A-V-I-D-R-E-T-L-K-M-D-I-L-S-R-D-I-I-R-A-N-I-I-K-R-L-L-H-V-I-N-Y-Y"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-S-Q-N-D-L-I-K-T-I-R-M-N-Y-L-F-D-F-Y-Q-A-L-L-T-K-K-Q-R-N-Y-L-E-L-F-Y-L-Q-D-Y-S-L-S-E-I-A-N-T-F-D-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-E-K-L-G-L-Y-R-N-F-E-Q-R-Q-N-L-Y-E-Q-I-K-Q-H-I-N-D-P-E-Q-I-K-K-Y-I-Q-A-L-E-D-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-I-F-L-G-L-I-H-I-Y-Q-R-F-I-S-P-L-T-P-A-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-V-V-Y-G-P-F-K-G-T-W-L-G-I-K-R-I-S-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-T-K-H-K-K-D-K-N-I-N-K"} +{"text": "### FUNCTION May play a key role in alkaline pH tolerance ### SEQUENCE -M-A-V-D-N-N-K-A-K-Q-A-Y-D-N-Q-T-G-V-N-E-K-E-Q-E-Q-R-Q-E-Q-Q-N-Q-Q-P-E-F-T-N-K-L-S-F-S-D-E-V-I-E-K-I-A-G-I-A-A-R-E-V-S-G-I-L-E-M-K-G-G-F-V-D-N-I-S-S-S-F-G-S-N-N-N-V-S-Q-G-V-S-V-E-V-G-E-K-Q-A-A-V-D-L-K-V-V-L-E-Y-G-E-S-A-P-K-I-F-R-K-V-T-D-L-V-K-E-Q-V-K-Y-I-T-G-L-D-V-V-E-V-N-M-R-V-E-D-V-M-T-K-K-E-W-S-Q-K-N-E-K-S-Q-S-S-N-N-E-D-K-G-L-Q"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-I-I-S-N-I-L-I-G-L-I-K-F-Y-K-M-V-I-S-P-Y-L-T-P-S-C-R-Y-L-P-T-C-S-E-Y-T-I-E-C-L-R-T-Y-G-L-V-K-A-I-S-K-S-T-K-R-I-F-S-C-H-P-I-K-I-L-G-G-G-E-G-F-D-P-V-N-K-E-F-K-A-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Y-F-F-I-K-T-I-N-K-Y-L-Y-K-L-I-Y-S-F-I-V-F-Y-Q-K-I-I-S-P-I-L-P-A-R-C-R-Y-Y-P-T-C-S-N-Y-G-K-Q-A-L-A-W-Y-G-V-W-N-G-S-L-L-L-L-K-R-I-G-R-C-H-P-L-G-G-H-G-I-D-F-V-P-L-P-L-A-S-Y-H-Y-Q-H-V-S-L-I-M-S-A-C-M-K-A-Q-G-L-Y-V-Y-R-D-N-N-G-Y-V-A-R-L-N-H-M-M-K-L-T"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-T-I-N-N-Q-P-E-P-T-N-E-Q-R-R-I-I-Y-Q-A-R-R-G-L-K-E-L-D-F-Y-F-E-P-Y-I-K-E-L-Y-L-T-A-E-A-A-E-Q-E-S-F-A-Q-M-L-T-H-E-D-P-D-L-L-D-Y-F-T-N-Q-S-R-P-E-D-D-A-M-W-A-L-V-N-K-I-K-T-W-R-H-S-K-S-L-S"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-A-T-F-N-P-Q-A-N-T-V-F-C-R-K-Y-Q-Q-D-L-P-K-M-P-H-P-P-F-P-N-K-K-G-Q-E-L-Q-E-T-V-S-E-K-A-W-K-E-W-L-E-Q-Q-T-M-L-I-N-E-N-H-L-S-M-L-D-P-K-A-K-Q-F-L-T-E-Q-R-D-K-F-L-D-N-E-D-Y-E-R-A-Q-G-W-T-P-E-S"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-P-K-V-I-T-I-S-D-D-V-Y-D-K-L-S-K-L-K-K-G-R-S-F-S-E-T-I-N-E-L-I-E-F-Y-N-K-N-R-K-G-N-K-D-V-L-L-Q-M-F-G-I-L-N-E-E-E-A-T-E-M-A-S-E-T-L-N-I-R-K-S-F-R-F-R-A-V-E-N-G-D-T"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-R-R-L-I-L-G-Y-Q-S-Y-L-S-P-L-K-M-G-P-T-C-R-F-E-P-T-C-S-N-Y-A-L-I-A-I-S-R-H-G-L-I-K-G-S-V-L-A-L-G-R-L-A-R-C-G-P-W-H-P-G-G-W-D-P-V-P-P-R-R-P-L-C-S-W-G-G-R-R-R"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-V-E-D-V-E-L-N-R-L-Y-W-H-S-R-R-G-M-L-E-L-D-V-L-L-V-P-F-V-R-E-V-Y-P-H-L-N-E-T-D-R-E-C-Y-R-K-L-L-E-C-E-D-Q-D-M-F-G-W-F-M-E-R-S-E-S-E-D-P-E-L-Q-R-M-V-R-M-I-L-D-R-V-Q-P-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-M-C-R-K-Y-Q-E-E-L-P-G-L-E-R-P-P-Y-P-G-A-K-G-Q-D-I-F-D-H-V-S-A-K-A-W-A-D-W-Q-K-H-Q-T-L-L-I-N-E-K-R-L-N-M-M-N-A-D-D-R-K-Y-L-Q-G-E-M-D-K-F-F-S-G-E-E-Y-A-K-A-D-G-Y-V-P-P-A-E"} +{"text": "### FUNCTION Mediates the regulatory switch from transcription to RNA replication Acts late in infection by inhibiting viral transcription and up-regulating RNA replication Inhibition of transcription by protein M2-2 requires phosphorylation of the phosphoprotein ### SEQUENCE -M-T-M-P-K-I-M-I-L-P-D-K-Y-P-C-S-I-T-S-I-L-I-T-S-R-C-R-V-T-M-Y-N-R-K-N-T-L-Y-F-N-Q-N-N-P-N-N-H-M-Y-S-P-N-Q-T-F-N-E-I-H-W-T-S-Q-D-L-I-D-T-I-Q-N-F-L-Q-H-L-G-V-I-E-D-I-Y-T-I-Y-I-L-V-S"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-I-P-D-K-N-A-S-S-E-D-S-D-E-A"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-K-L-F-E-E-S-N-E-D-V-V-E-I-Q-R-A-N-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-A-T-G-Y-I-N-H-L-L-Q-I-I-G-P-S-I-S-Q-Q-Q-A-Y-Y-I-L-D-G-L-L-D-K-G-L-I-S-E-R-E-A-R-M-I-Q-V-I-V-D-R-E-T-L-K-M-D-V-V-A-R-D-I-I-R-A-N-I-L-K-R-L-L-P-I-I-N-F-Y"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-K-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-T-L-L-T-E-K-Q-R-N-Y-M-E-L-F-Y-L-R-D-Y-S-L-S-E-I-A-E-T-F-D-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-A-K-L-N-L-Y-E-K-F-E-Q-R-R-K-I-Y-D-D-M-K-Q-T-L-N-D-S-K-K-L-E-Q-Y-I-N-Q-L-E-E-L-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-K-L-F-L-G-I-I-H-I-Y-Q-R-Y-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-E-V-Y-G-P-F-K-G-G-Y-M-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-H-R-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-E-T-H-S-L-G-T-K-I-L-I-K-I-I-R-L-Y-Q-I-M-I-S-P-F-I-G-A-R-C-R-F-V-P-T-C-S-C-Y-G-I-E-A-L-K-T-H-G-L-L-K-G-G-W-L-T-L-K-R-V-L-K-C-H-P-L-N-A-G-G-F-D-P-V-P-P-K-T-N-N-N-D-E-K-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-E-Y-L-K-K-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-S-V-S-K-Q-A-W-G-E-W-I-K-K-Q-T-M-L-V-N-E-K-K-L-N-M-M-N-A-E-H-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-K-D-V-H-I-E-G-Y-V-P-P-S-N"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-E-K-Y-N-K-L-R-I-E-W-D-C-R-R-G-M-L-E-L-D-K-I-I-M-P-F-Y-L-K-H-F-D-E-L-T-D-D-K-K-D-I-F-I-R-L-L-A-S-T-D-L-Q-L-F-S-W-F-F-N-R-G-K-S-S-D-S-E-I-Q-S-M-V-E-Y-I-Q-N-V-Q-K-I-T-T-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-R-I-L-L-L-L-L-R-F-Y-Q-Y-F-I-S-P-L-L-G-N-N-C-R-F-H-P-T-C-S-E-Y-A-K-E-A-I-T-T-H-G-T-L-K-G-L-W-L-T-F-K-R-I-I-K-C-Q-P-F-C-N-G-G-Y-D-A-V-P-L-S-I-K-N-S-K-L-F-N-K-K-I"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Upon expression in Ecoli neutralizes the effect of cognate toxin VapC1, partially inhibits the RNase activity of VapC1 in vitro ### SEQUENCE -M-Q-L-F-L-R-I-N-M-A-Q-I-I-R-A-T-E-F-V-R-S-F-S-D-I-M-N-R-V-Y-Y-K-G-E-S-F-D-V-Q-K-G-N-H-I-V-A-R-I-T-P-A-E-T-K-P-S-I-A-V-R-D-L-E-E-A-F-K-N-G-P-H-L-D-P-E-D-A-D-Q-F-M-K-D-I-E-E-I-R-R-S-T-R-Q-D-I-K-K-L-V-E-R-W-D"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-E-K-E-M-D-E-D-T-L-L-K-K-L-R-W-R-C-R-R-G-M-R-E-L-D-Q-L-F-G-R-Y-L-D-R-R-W-A-Q-A-P-A-A-E-R-A-V-F-L-Q-L-L-D-C-E-D-D-K-L-W-R-W-F-M-G-Y-E-A-C-P-D-A-D-N-A-A-L-I-A-D-I-R-A-M-P-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Y-H-W-Q-V-I-G-R-L-L-I-A-L-L-R-F-Y-K-R-F-I-S-P-L-L-G-P-R-C-R-F-A-P-S-C-S-E-Y-A-M-T-A-I-A-R-F-G-P-L-R-G-S-W-L-A-A-R-R-L-G-R-C-H-P-F-H-P-G-G-F-D-P-V-P-D-A-P-T-S-S-P-S-S-C-R-C-K-G-P-H-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-Q-Y-Q-Q-C-D-T-E-G-L-D-F-A-P-Y-P-G-E-L-G-Q-R-I-F-A-Q-I-G-K-A-G-W-Q-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-D-P-K-H-R-A-F-L-E-A-E-L-Q-K-F-L-F-E-R-N-A-D-K-P-E-G-Y-V-D-P-L-G-E-E"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-L-S-S-W-V-R-C-L-G-A-L-L-F-L-A-S-V-A-Q-A-Q-F-Q-F-F-E-H-M-F-G-G-G-H-Q-E-H-H-Q-Q-N-T-Q-N-S-A-S-D-S-A-R-Y-Q-Q-L-W-E-G-T-N-C-N-K-Y-L-C-P-G-T-L-A-C-V-D-F-P-H-H-C-P-C-A-H-P-N-V-E-D-K-V-E-L-G-E-G-S-A-V-C-I-S-K-G-G-Y-K-P-G-E-A-A-R-K-I-E-L-A-R-K-G-L-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-L-A-L-V-P-I-Q-F-Y-R-Y-A-I-S-P-L-M-A-S-H-C-R-F-Y-P-S-C-S-C-Y-A-Y-E-A-I-E-N-H-G-L-L-R-G-G-W-L-S-I-R-R-L-G-R-C-H-P-W-N-P-G-G-Y-D-P-V-P-A-V-P-T-S-R-S-S-S-M-A-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-M-C-R-K-Y-K-E-E-L-P-G-L-E-R-A-P-Y-P-G-A-K-G-E-D-I-F-N-H-V-S-Q-K-A-W-A-D-W-Q-K-H-Q-T-L-L-I-N-E-R-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-T-E-M-D-K-F-L-S-G-E-E-Y-A-Q-A-E-G-Y-V-P-P-E-K"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-V-E-D-V-E-L-N-R-L-Y-W-H-S-R-R-G-M-L-E-L-D-V-L-L-V-P-F-V-R-E-V-Y-P-H-L-N-D-V-D-R-D-L-Y-R-R-L-L-T-C-E-D-Q-D-M-F-G-W-F-M-Q-R-A-E-S-E-D-A-E-L-Q-R-M-V-R-M-I-L-D-R-V-Q-P-Q"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-D-W-F-T-R-I-E-G-V-D-E-L-E-S-A-Q-S-F-F-D-F-F-E-L-E-V-D-P-V-L-L-R-S-R-H-L-H-I-M-A-Q-F-N-Q-R-L-T-A-A-V-P-V-H-F-V-D-E-E-E-S-D-R-A-D-W-R-L-A-R-R-L-L-A-E-S-Y-Q-H-T-V-A-G-P-L-N-T-Q-S-G-L-A-V-Y-Q-R-N-N-G-S-F-I-G-W-N-D-L-L-E-V-R-P"} +{"text": "### FUNCTION Involved in nodulation of a particular host, Mlupulina ### SEQUENCE -M-R-S-K-P-P-S-W-G-H-E-G-I-I-S-R-H-P-T-K-L-L-P-I-G-L-P-G-T-G-D-L-F-A-G-S-I-V-A-G-L-A-R-G-V-P-L-P-R-A-V-A-I-A-Q-N-L-T-S-R-A-Q-D-H-A-N-A-L-G-A-G-E-V-V-L-S-E-P-E-S-R-R-A-L-V-A-L-D-P-N"} +{"text": "### FUNCTION Responsible for the nodulation efficiency and competitive ability of strain GR4 on alfalfa roots ### SEQUENCE -M-A-A-L-R-Q-V-A-F-Y-G-K-G-G-I-G-N-S-K-R-K-P-E-L-V-T-A-S-I-E-D-R-S-A-G-S-P-S-K-N-K-M-H-F-Q-S-R-M-N-V-A-A-S-M-R-G-G-D-G-L-P-P-S-V-R-C-R-L-H-L-E-D-G-T-T-R-G-E-R-K-E-R-T-R-L-A-A-T-F-Q-S-V-S-E-E-R-P-R-L-H-M-P-R-R-V-T-T-T-H-T-T-L-F-V-T-F-V-G-F-T-T-P-I-V-P-S-T-V-W-S-I-S-R-S-N-H-L-K-Q-S-N"} +{"text": "### FUNCTION Involved in the transcriptional regulation of pufB ### SEQUENCE -M-V-P-Y-R-N-P-R-H-Q-H-V-A-S-V-L-R-S-G-G"} +{"text": "### FUNCTION Putative control of replication message ### SEQUENCE -M-T-F-N-K-I-F-K-Y-L-I-S-L-L-F-L-S-I-L-F-H-T-I-I-H-K-N-N-L-V-F-S-K-T-M-H-K-K-V-A-F-F-S-F-S-F-F-F-V-W-I-R-H-L-K-R-Y-N-S-M-L-E-K-A-T-F-F-V-L-Q-T-S-Y-T-N-E-L-K-G-L-Y-I-A-G-N-S-Y-P-Y-Y-Q-D-K-K-K-L-V-F-N-S-F-Q-K-P-F-K-N-H-Q-S-T-K-I-P-R-E"} +{"text": "### FUNCTION May be a component of the Integrator complex, a complex involved in the small nuclear RNAs U1 and U2 transcription and in their 3'-box-dependent processing ### SEQUENCE -M-N-K-I-F-G-V-K-I-D-S-Q-Q-K-K-R-Q-Q-S-N-K-N-L-T-V-F-N-N-G-R-Y-L-I-Y-I-G-D-I-H-F-D-R-K-F-H-R-E-A-L-R-Y-Y-L-L-G-C-G-L-E-T-A-F-Y-S-D-P-V-K-T-S-V-T-N-S-K-Y-L-T-F-L-S-R-R-I-F-D-C-F-Y-F-L-R-A-P-M-Q-A-I-V-V-S-Q-F-F-G-N-L-N-Q-T-C-L-V-S-F-K-I-I-Q-E-E-Y-Y-Q-L-D-T-N-Y-F-Q-Y-I-W-E-L-P-L-L-E-I-L-L-T-T-F-T-K-Q-K-D-L-K-K-I-Y-L-I-N-Q-I-I-S-N-P-I-I-N-E-N-N-H-P-D-I-R-K-N-F-I-K-N-T-K-H-N-F-W-K-A-I-S-S-N-Y-L-L-Q"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-M-K-K-L-L-L-T-L-I-K-L-Y-R-I-L-I-S-P-L-F-P-P-S-C-R-F-Q-P-T-C-S-Q-Y-A-L-D-A-V-E-I-H-G-V-W-R-G-S-C-L-A-L-K-R-I-L-R-C-H-P-L-H-P-G-G-Y-D-P-V-P-N-P-E-Q-G-K-I-S-S"} +{"text": "### FUNCTION Chaperone protein which promotes assembly of the 20S proteasome May cooperate with psmg1-psmg2 heterodimers to orchestrate the correct assembly of proteasomes ### SEQUENCE -M-N-S-L-L-I-D-S-S-N-P-S-Y-D-A-M-N-N-D-N-L-K-N-S-I-E-K-N-H-P-V-K-S-K-V-L-S-K-K-I-N-N-V-D-T-D-I-A-I-S-S-F-A-D-A-I-F-I-T-I-S-Q-N-Q-K-F-N-T-W-I-R-A-S-K-S-D-G-I-L-L-D-E-P-S-Y-Q-I-D-T-L-L-G-N-N-Q-D-V-L-F-S-I-Y-A-R-Q-L-I-E-N-I-G-E-T-S-N-K-S-L-M-L-S-I-S-I-T-D-K-S-K-D-T-F-K-Q-I-L-S-T-I-F-E-N-K-V-W"} +{"text": "### FUNCTION Transcriptional regulator that plays an important role in general stress response ### SEQUENCE -M-I-Q-E-I-I-E-K-K-L-H-S-E-L-Q-P-S-Y-L-K-V-I-N-E-S-Y-M-H-N-V-P-P-G-S-E-S-H-F-K-V-I-V-V-S-D-S-F-A-G-Q-R-L-I-G-R-H-R-Q-V-H-Q-I-L-A-D-E-L-D-N-H-I-H-A-L-A-I-H-T-Y-T-D-E-E-W-K-R-E-Q-D-G-A-P-D-S-P-M-C-M-G-G-G-H"} +{"text": "### FUNCTION Not essential for flagellar formation and function ### SEQUENCE -M-L-T-C-L-S-R-R-V-L-V-G-L-F-S-I-G-I-L-P-L-N-A-M-A-S-G-S-W-V-A-D-D-I-G-I-T-Q-S-V-R-G-V-A-I-S-A-K-P-L-Q-S-P-V-A-L-A-Q-D-N-A-R-I-V-S-I-S-W-R-Y-Q-L-M-S-A-A-P-D-G-L-Q-V-K-L-C-T-P-T-R-C-M-P-L-E-G-G-S-G-L-S-R-G-L-A-G-E-A-A-A-T-Q-L-T-F-I-Y-F-I-A-G-K-G-R-V-N-P-P-L-Q-V-I-N-H-Q-V-I-V-N-Y-R"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-K-I-A-F-L-F-R-T-S-P-H-G-T-S-I-S-R-E-G-L-D-A-I-L-A-A-T-A-F-C-E-P-N-D-I-G-I-F-F-I-D-D-G-V-L-N-L-I-D-N-Q-Q-P-E-I-I-Q-Q-K-D-F-I-R-T-F-K-L-L-D-L-Y-D-V-E-Q-R-F-I-C-T-A-S-L-Q-K-F-K-L-D-N-R-E-L-I-L-S-C-E-K-I-D-R-S-L-L-L-E-K-L-N-Q-A-G-K-L-F-T-F"} +{"text": "### FUNCTION Putative toxin component of a putative type VII toxin-antitoxin system Its cognate antitoxin might be MJ0141 ### SEQUENCE -M-R-L-K-I-M-E-L-R-Y-K-R-E-L-E-K-L-I-E-K-A-E-K-S-L-E-A-S-E-N-L-Y-N-S-E-F-Y-D-F-A-V-S-R-I-Y-Y-S-M-F-Y-C-V-K-A-L-L-L-T-K-E-I-N-P-K-K-H-S-G-V-L-K-M-F-A-K-E-F-I-K-T-N-E-L-D-V-E-L-F-E-Y-I-N-E-A-Y-N-Y-R-Q-T-A-D-Y-D-A-T-I-E-I-K-K-E-E-A-E-Y-L-L-H-K-G-H-I-F-L-N-K-T-K-K-Y-L-I-S-K-N-I-L-K-G-E-N-D-N-T-K-S"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-L-I-V-Y-F-S-S-R-S-G-N-T-H-R-F-V-E-R-L-G-V-R-S-S-R-I-P-L-E-A-S-G-A-L-Q-V-R-E-P-F-V-L-V-T-P-T-Y-G-G-G-S-T-K-G-A-V-P-N-P-V-I-R-F-L-N-D-A-D-N-R-A-L-I-R-G-V-I-A-A-G-N-S-N-F-G-E-A-F-C-I-A-G-N-I-I-S-A-K-C-G-V-P-Y-L-Y-R-F-E-L-L-G-T-A-E-D-V-G-N-V-R-N-G-M-E-Q-F-W-T-R-Q-T-Q-A"} +{"text": "### FUNCTION Might be involved in Fe ### SEQUENCE -M-Y-P-L-A-F-A-K-E-G-E-E-V-I-V-K-K-I-D-A-G-C-G-A-M-Q-R-L-V-S-M-G-I-N-I-G-S-K-L-K-V-I-R-N-Q-N-G-P-V-I-I-S-T-K-G-S-N-I-A-I-G-R-G-L-A-M-K-I-M-V-E-D-A-E-Y-G-G-E-N-E-K-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-S-C-G-G-K-H-T-G-K-G-A-P-K-P-Y-S-R-N-F-T-D-P-W-R-K-T-P-G-R-L-F-G-T-A-L-I-R-F-Y-Q-I-T-L-S-S-L-I-G-N-S-C-R-H-L-P-T-C-S-E-Y-A-Y-E-A-I-A-R-H-G-L-W-R-G-G-W-M-G-F-F-R-V-V-R-C-G-P-F-G-T-H-G-F-D-P-V-P-R-E-L-S-P-D-L-K-W-Y-M-P-W-R-Y-W-R-C-S-A-S-R-I-G-K"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-N-N-N-N-V-Y-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-Q-A-E-G-R-P-V-D-I-Q-A-V-T-G-N-M-D-E-E-H-R-D-W-F-C-K-R-Y-A-L-Y-C-Q-Q-A-T-Q-A-K-R-L-E-L-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-Q-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-C-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-K-G-V-N-E-F-W-Q-Q-L-P-R-S-A"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-I-L-T-T-S-R-K-P-S-Q-R-T-R-S-F-A-R-D-L-E-R-T-L-N-I-P-Y-V-Q-R-G-K-L-S-L-K-E-I-F-E-I-D-K-H-V-L-L-I-G-E-F-K-A-N-P-G-T-L-V-V-Y-D-V-E-N-E-K-R-L-S-S-F-I-S-V-K-L-Q-R-E-I-C-G-E-K-I-Y-N-D-D-G-I-R-I-K-I-S-R-E-L-K-D-N-E-E-F-Q-K-Y-Y-E-I-Y-D-E-F-L-F-Q-H-L-N-I-N-E-D-S-D-I-T-L-R-L-E-K-D-P-K-Y-L-F-A-I-Q-F-Y-K-G-R-V-K-I-G-P-L-I-R-I-K-S-I-K-L-F-D-S-L-L"} +{"text": "### FUNCTION Putative toxin component of a putative type VII toxin-antitoxin system Its cognate antitoxin might be MJ0604 ### SEQUENCE -M-K-A-L-L-N-K-D-I-R-E-E-I-Q-A-L-I-E-I-A-E-E-N-L-S-A-A-K-I-L-F-E-N-K-L-Y-R-D-A-V-A-R-A-Y-Y-A-I-F-H-S-A-K-A-L-L-L-T-K-N-L-N-P-K-K-H-A-G-V-I-K-M-F-G-L-Y-F-V-N-E-G-Y-I-E-E-I-Y-G-R-I-I-T-K-S-Y-N-L-R-W-K-A-D-Y-T-T-D-K-P-T-E-E-E-A-E-S-I-I-Y-E-A-E-M-F-V-D-R-I-K-K-A-L-K-E-I-L"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-K-Q-W-K-Y-L-L-K-K-S-F-I-K-D-L-K-E-L-P-K-N-I-Q-E-K-I-K-K-L-V-F-E-E-I-P-N-K-N-N-P-P-E-I-P-N-V-K-K-L-K-G-A-D-S-Y-Y-R-I-R-V-G-D-Y-R-I-G-F-K-Y-E-N-G-K-I-V-F-Y-R-V-L-H-R-K-Q-I-Y-K-R-F-P"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-E-I-V-V-D-A-I-Y-E-K-G-V-L-K-L-K-K-S-I-N-L-P-E-G-C-E-V-E-I-K-I-I-P-K-K-I-S-E-K-T-F-G-I-L-K-L-S-D-K-E-I-K-E-I-L-E-E-I-E-N-G-G-E"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-I-N-M-A-T-I-T-I-D-D-D-V-Y-K-E-L-L-K-L-K-G-R-K-S-V-S-E-F-I-K-E-L-L-E-E-R-K-R-K-N-L-D-V-F-M-I-A-F-G-S-R-S-E-E-D-V-E-K-L-K-K-E-L-K-E-A-E-K-W-M-Q-S-L-I-Q-V"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-I-L-M-V-K-A-I-V-D-I-T-D-E-N-N-R-I-I-N-I-V-K-A-K-Y-N-L-R-D-K-S-Q-A-I-N-K-I-I-E-E-Y-A-E-F-L-L-E-D-E-L-K-P-E-Y-I-E-K-I-R-N-I-M-K-N-E-K-P-I-Y-I-G-S-I-E-N-L-K-K-R-Y-L-G-E"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-Y-E-I-E-I-M-P-S-L-D-K-I-L-Q-K-L-S-K-R-D-K-K-K-L-K-A-I-L-K-K-M-E-E-I-T-Q-N-P-H-H-Y-K-N-L-R-H-P-L-N-D-F-K-R-V-H-I-D-K-S-F-V-L-V-F-T-V-D-E-N-N-K-T-V-I-F-V-D-F-D-H-H-D-N-I-Y-K-K-K-K-L-F-K-D"} +{"text": "### FUNCTION Putative toxin component of a putative type VII toxin-antitoxin system Its cognate antitoxin might be MJ1305 ### SEQUENCE -M-E-D-S-G-F-N-I-K-Y-A-K-L-F-I-K-R-A-E-E-D-L-E-V-A-K-V-L-L-K-T-N-H-Y-P-D-S-V-Y-H-S-Q-Q-C-V-E-K-A-V-K-A-V-L-I-L-N-G-I-I-F-R-R-H-V-V-S-G-V-F-R-N-V-I-Y-E-M-K-I-E-D-S-W-K-E-K-L-L-N-L-I-P-K-I-E-S-L-E-E-H-W-V-M-P-R-Y-P-E-P-Y-F-G-E-L-W-N-P-L-E-E-Y-T-K-E-D-A-E-E-C-L-K-D-A-E-N-V-L-E-V-I-K-D-F-L-K-E-K-Y-G-L-K-Q-I"} +{"text": "### FUNCTION May be involved in control of expression of the type II restriction enzyme MjaV and/or its methyltransferase MMjaV ### SEQUENCE -M-S-K-S-G-N-K-N-Q-N-C-P-K-C-N-N-S-P-W-I-Q-R-A-N-N-F-I-A-Q-N-Q-N-V-Q-T-G-T-K-E-Y-Y-Q-V-E-A-V-K-Y-L-L-N-N-G-H-C-G-I-D-C-R-A-K-I-S-D-I-I-K-G-I-N-Y-P-K-N-R-E-A-F-Q-H-E-V-L-I-P-L-K-Q-Y-G-I-I-A-T-L-V-Y-P-G-R-K-G-G-V-F-I-P-C-N-N-D-E-I-K-K-V-A-K-Q-V-F-K-R-I-E-S-E-L-E-N-L-E-G-S-A-T-G-V-Q-N-I-K-N-L-A-N-S-L-K-T-T-V-H-N-L-K-N-T-I"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-F-Q-K-L-I-V-I-T-F-A-I-A-L-A-S-A-N-I-F-D-F-L-N-N-F-N-T-G-G-R-Q-Q-Q-N-Q-G-V-R-T-P-Q-E-Y-E-S-V-V-L-N-S-Q-C-D-K-Y-L-C-P-D-T-G-L-C-V-E-A-P-K-F-C-P-C-P-Y-P-S-S-Q-I-R-C-F-L-P-D-G-R-F-V-C-I-S-K-P-A-G-E-G-I-S-E-K-Y-N-D-P-K-T-N-W-K-I-D-A-K-D-D-N-I-R-D-C-G-W-V-N-R-A-W-R-G-L-V"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-Y-S-A-E-E-K-A-R-V-K-W-A-C-R-R-G-M-L-E-L-D-V-V-I-M-P-F-F-D-E-C-F-E-E-L-T-E-A-E-Q-Q-A-F-V-S-L-L-E-C-D-D-P-D-L-F-T-W-V-M-G-H-G-R-S-D-N-L-A-H-A-S-M-V-D-K-I-V-E-H-N-L-S-K-L-R"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-P-L-S-V-E-Q-A-L-A-N-F-S-Q-R-Y-V-E-A-W-K-A-Q-H-D-C-L-P-I-N-E-E-L-V-G-L-A-S-P-C-I-E-E-T-R-D-L-E-I-S-W-Q-P-I-V-R-D-E-A-I-R-L-H-N-I-E-Q-G-I-E-L-D-L-H-D-D-F-H-A-F-Y-G-T-Q-Y-S-A-D-M-T-A-K-F-E-D-M-N-I-E-L-L-Q-V-W-S-D-E-D-L-E-R-L-Q-G-N-M-L-G-H-L-V-M-Q-R-R-L-K-L-V-P-T-L-F-V-A-V-T-D-D-E-M-E-V-V-S-I-C-N-Q-S-G-E-V-I-L-D-R-V-G-T-K-N-R-T-V-L-A-A-N-M-A-E-F-L-N-K-L-E-P-V-I-A-A"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-V-R-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-D-P-E-H-R-K-L-L-E-T-E-M-E-G-F-L-F-D-G-K-D-V-V-I-D-G-Y-T-P-P-S-E"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-N-R-L-G-F-V-F-Q-S-A-P-H-S-T-S-K-G-R-E-G-L-D-A-I-L-A-A-S-A-Y-S-E-D-I-Q-I-F-F-I-G-D-G-V-L-Q-L-L-K-N-Q-E-P-E-K-I-L-S-R-D-Y-I-S-G-F-K-M-L-E-L-Y-D-L-E-E-I-F-V-C-Q-N-A-M-G-N-R-G-I-K-E-E-Y-L-L-I-D-V-D-S-I-S-N-K-D-I-N-E-K-L-S-Q-C-D-Q-I-M-V-F"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-F-L-L-S-K-L-L-L-G-L-I-R-F-Y-Q-Y-C-I-S-P-L-I-P-P-R-C-R-Y-T-P-T-C-S-Q-Y-A-V-E-A-V-K-K-Y-G-A-F-K-G-L-R-L-A-I-K-R-I-A-R-C-H-P-F-G-G-H-G-H-D-P-V-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-F-C-V-K-L-N-K-E-A-E-G-M-K-F-P-P-L-P-N-E-L-G-K-R-I-F-E-N-V-S-Q-E-A-W-A-A-W-T-R-H-Q-T-M-L-I-N-E-N-R-L-S-L-A-D-P-R-A-R-E-Y-L-A-Q-Q-M-E-Q-Y-F-F-G-D-G-A-D-A-V-Q-G-Y-V-P-Q"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-H-Y-Q-Q-S-D-A-E-G-L-D-F-V-P-Y-P-G-E-L-G-Q-R-I-F-A-H-I-G-K-T-A-W-Q-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-D-P-K-H-R-A-F-L-E-T-E-L-Q-K-F-L-F-E-R-N-A-D-K-P-D-G-Y-V-A-P-L-G-E-E"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-Q-R-H-R-P-L-G-Q-V-P-L-S-F-S-A-R-H-T-A-R-W-R-D-E-M-D-E-Q-T-R-L-K-K-L-R-W-R-C-R-R-G-M-R-E-L-D-Q-L-F-G-R-Y-L-D-Q-R-W-A-Q-A-P-D-A-E-R-A-V-F-L-Q-L-L-D-C-E-D-D-K-L-W-R-W-F-M-G-Y-E-A-C-P-D-V-A-N-A-A-L-I-A-D-I-R-A-L-P-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Accessory element involved in the expression of sarA and several virulence factors Modulates SarA production and/or function in a strain-dependent manner Affects the transcription of the accessory gene regulator ### SEQUENCE -M-K-Y-L-I-L-S-L-V-A-N-L-L-V-F-G-V-L-S-A-I-G-L-N-I-N-I-L-A-A-M-M-I-V-L-V-I-P-I-M-I-S-G-I-L-F-F-K-T-N-I-D-K-T-Y-I-F-F-N-I-I-F-I-D-F-Y-Y-Y-I-Y-N-V-H-L-M-T-L-P-K-F-N-N-Y-I-K-A-E-M-M-E-L-E-D-I-D-V-L-I-T-S-K-D-F-G-F-D-E-I-L-F-Y-T-L-Y-L-L-L-I-L-I-V-L-Y-Y-L-K-K-Q-V-K-H-K-I"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-R-L-F-E-E-S-N-E-D-V-V-E-I-Q-R-A-N-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-A-T-G-Y-I-N-H-L-L-Q-L-I-G-P-S-I-S-Q-Q-Q-A-Y-Y-I-I-D-G-L-L-D-K-M-L-I-N-E-R-E-A-K-M-I-Q-A-V-I-D-R-E-T-L-S-M-D-M-V-S-R-D-I-I-R-A-N-I-L-K-R-L-L-P-V-I-N-Y-Y"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-V-P-D-K-N-A-T-S-E-D-S-E-E-A"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-R-N-E-I-F-E-K-I-M-R-L-E-M-N-V-N-Q-L-S-K-E-T-S-E-L-K-A-L-A-V-E-L-V-E-E-N-V-A-L-Q-L-E-N-D-N-L-K-K-V-L-G-N-D-E-P-T-T-I-D-T-A-N-S-K-P-A-K-A-V-K-K-P-L-P-S-K-D-N-L-A-I-L-Y-G-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-F-C-L-E-V-L-S-D"} +{"text": "### FUNCTION Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host ### SEQUENCE -M-N-Q-H-V-K-V-T-F-D-F-T-N-Y-N-Y-G-T-Y-D-L-A-V-P-A-Y-L-P-I-K-N-L-I-A-L-V-L-D-S-L-D-I-S-I-F-D-V-N-T-Q-I-K-V-M-T-K-G-Q-L-L-V-E-N-D-R-L-I-D-Y-Q-I-A-D-G-D-I-L-K-L-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-L-L-S-L-V-V-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-Q-Y-T-R-E-A-I-E-Y-H-G-A-L-K-G-L-Y-L-G-V-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-N-S-K-T-T-H-H-H"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-K-N-Y-L-E-L-F-Y-L-Q-D-Y-S-L-S-E-I-A-D-T-F-E-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-S-K-L-R-L-Y-Q-R-F-E-K-R-R-E-L-Y-N-L-M-K-Q-S-L-N-Q-P-E-L-L-K-Q-Y-I-T-Q-L-E-E-L-E"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-R-L-F-E-E-A-D-E-D-V-V-E-I-Q-R-A-H-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-A-T-G-Y-I-N-H-L-L-Q-L-I-G-P-S-I-S-Q-Q-Q-G-Y-Y-V-I-D-G-L-L-D-K-G-L-I-N-E-R-E-A-K-M-I-Q-T-I-I-D-R-E-T-L-K-M-D-V-V-A-R-D-I-I-R-A-N-I-L-K-R-L-L-P-V-I-N-Y-Y"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-R-N-E-L-F-E-R-L-M-K-L-E-H-H-V-E-Q-L-T-T-D-M-S-E-L-K-D-L-T-V-E-L-V-E-E-N-V-A-L-Q-V-E-N-E-N-L-K-R-L-M-N-K-T-E-E-S-V-E-T-H-L-D-K-D-N-Y-K-H-V-K-T-P-S-P-S-K-D-N-L-A-M-L-Y-R-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-L-C-L-N-V-L-S-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-C-L-K-I-L-R-F-Y-Q-K-F-L-S-P-L-K-P-A-A-C-R-Y-Y-P-S-C-S-E-Y-A-L-W-Q-F-Q-K-K-N-F-F-L-A-F-F-S-T-F-F-R-V-L-R-C-N-P-F-F-K-G-G-F-D-Y-P-R-V-S-K-N-F-Y-P-I-N-L-C-F-K-P-I-F-L-A-K-K-Q-L-C-F-L-Y-I-P-Y-K-N-K-S-F-Y-L-I-K-I-I-F-K-R-T-N-Q"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-G-K-T-I-T-I-A-D-D-V-Y-Y-E-L-V-K-M-K-G-K-K-S-F-S-E-L-L-R-E-L-I-G-K-K-K-K-G-N-L-D-V-L-M-I-A-F-G-T-R-T-P-E-E-V-E-E-L-K-K-E-L-K-E-V-E-E-W-M-D-S-W-T-P-A-S-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-Q-W-L-I-W-C-I-R-F-Y-Q-R-F-L-S-P-L-K-P-P-T-C-R-F-Y-P-T-C-S-N-Y-G-I-E-A-I-R-R-F-G-A-I-K-G-G-W-L-T-A-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-E-S-S-E-H-A-K-R-N-K-I-T"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-M-R-M-N-Y-L-Y-D-F-Y-Q-A-L-L-T-P-K-Q-R-N-Y-M-A-L-Y-Y-L-D-D-Y-S-L-G-E-I-A-E-Q-Y-E-V-S-R-Q-A-V-Y-D-N-I-R-R-T-E-A-M-L-E-Q-Y-E-E-K-L-G-L-L-R-K-Y-E-R-R-R-Q-I-I-E-R-L-K-D-Y-I-S-R-R-Y-G-A-D-A-E-L-A-A-L-V-R-E-L-D-E-L-D"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-V-T-D-V-R-L-R-R-V-N-T-E-G-R-M-K-A-I-A-S-I-T-L-D-N-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-A-T-R-G-K-I-Q-E-A-I-L-A-E-Y-H-R-L-G-K-L-E-E-E-L-E-E-A-G-A-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-F-K-Q-L-L-Y-N-L-P-T-H-L-C-C-G-L-I-H-L-Y-R-W-T-I-S-P-L-L-G-S-P-C-R-F-F-P-S-C-S-Q-Y-A-L-Q-A-L-K-H-H-K-C-I-R-G-L-W-L-T-I-K-R-I-G-K-C-G-P-W-H-P-G-G-I-D-L-V-P-M-T-T-L-E-E-A-L-D-V-S-Q-V-T-N-D-D-D-S-G-D-S-H-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-L-L-S-Y-I-L-L-L-P-I-Y-F-Y-R-A-C-I-S-P-M-T-P-P-S-C-R-F-T-P-T-C-S-Q-Y-A-I-E-A-I-K-K-H-G-P-F-K-G-L-Y-L-A-V-R-R-I-L-R-C-H-P-W-G-G-S-G-Y-D-P-V-P"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-D-I-M-E-K-Y-A-D-D-S-Y-L-Q-E-Q-I-A-I-L-S-S-I-D-N-R-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-M-K-K-F-L-I-A-L-V-K-A-Y-Q-R-W-I-S-P-L-F-P-L-S-C-R-F-C-P-T-C-S-V-Y-M-I-Q-A-I-E-K-H-G-L-K-G-V-L-M-G-I-A-R-I-L-R-C-H-P-L-S-E-T-G-D-D-P-V-P-D-Y-F-S-L-K-R-K-K-T-P-L-D-N"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-D-I-M-E-K-Y-A-D-D-S-Y-L-Q-E-Q-I-A-I-L-S-S-I-D-N-R-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-M-K-K-F-L-I-A-L-V-K-A-Y-Q-R-W-I-S-P-L-F-P-L-S-C-R-F-C-P-T-C-S-V-Y-M-I-Q-A-I-E-K-H-G-L-K-G-V-L-M-G-I-A-R-I-L-R-C-H-P-L-S-E-T-G-D-D-P-V-P-D-Y-F-S-L-K-R-K-K-T-P-L-D-N"} +{"text": "### FUNCTION Has antibacterial activity against both Gram-positive and Gram-negative bacteria ### SEQUENCE -T-G-S-G-K-Y-N-I-L-H-N-D-N-H-N-L-D-L-T-G-K-F-L-E-C-S-R-S-N-P-N-L-S-D-Y-N-K-Y-S-A-I-L-D-Y-L-Y-K-D-K-L-S-A-S-L-G-V-A-H-S-G-L-L-D-R-T-D-L-S-A-L-G-K-V-N-L-L-N-D-K-N-T-R-L-D-L-F-G-G-L-T-K-S-M-S-P-K-F-D-S-G-L-K-P-N-F-G-L-Q-L-E-S-S-F"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-L-L-L-L-A-L-I-Q-F-Y-R-R-W-I-S-P-L-T-P-A-S-C-R-F-Y-P-T-C-S-Q-Y-G-L-E-A-I-D-R-F-G-P-L-K-G-S-W-L-T-L-C-R-I-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P-P-L-P-S-C-S-C-G-K-S-P-C-D"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-L-I-K-N-N-D-L-I-F-S-S-V-D-K-I-K-Y-S-A-R-R-G-M-L-E-L-D-I-I-L-A-P-Y-L-N-N-C-Y-M-H-E-D-L-A-N-K-K-L-F-V-E-F-L-T-S-E-D-S-D-M-F-D-W-L-F-K-G-V-T-P-P-Q-R-Y-Q-Q-L-I-D-K-I-I-K-E-K-K-K-F-N-Q-T-K-L-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-K-V-F-C-K-K-Y-H-Q-E-L-D-A-I-P-F-Q-P-L-P-G-E-L-G-K-K-I-H-N-E-I-S-N-K-A-W-Q-A-W-L-A-H-Q-T-I-L-I-N-E-Y-R-L-N-L-I-E-P-K-A-K-E-F-L-K-E-E-M-H-K-F-L-F-E-G-K-E-E-K-P-E-Q-F-S-E-I"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-I-N-L-Y-R-Y-C-I-S-P-F-I-P-A-R-C-R-Y-Y-P-T-C-S-E-Y-A-L-E-A-L-K-T-H-G-I-L-K-G-L-Y-L-T-T-R-R-L-L-R-C-H-P-L-S-K-R-D-Y-Y-D-L-V-P-C-K-N-K-K-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-A-L-V-L-G-L-L-R-V-Y-R-Y-A-I-S-P-M-L-G-R-N-C-R-F-H-P-C-C-S-E-Y-A-Q-E-A-V-E-R-H-G-A-M-R-G-G-W-L-A-L-K-R-V-G-R-C-H-P-F-H-P-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-N-N-N-N-V-Y-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-Q-A-E-G-R-P-V-D-I-Q-A-V-T-G-N-M-D-E-E-H-R-D-W-F-C-K-R-Y-A-L-Y-C-Q-Q-A-T-Q-A-K-K-L-E-L-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-E-L-T-A-Q-A-L-K-A-F-T-T-R-Y-C-D-A-W-Q-E-K-H-G-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-S-T-R-D-A-V-Y-W-Q-P-Q-P-F-E-G-E-E-N-V-N-A-V-E-R-A-F-D-I-M-V-Q-P-A-L-H-A-F-Y-T-T-Q-F-A-G-D-M-P-A-Q-F-A-D-E-K-L-T-L-L-Q-T-W-S-Q-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-Q-E-N-E-L-E-V-I-S-V-C-N-L-S-G-E-V-I-K-E-T-L-G-T-R-N-R-T-V-L-A-A-T-L-A-E-F-L-T-Q-L-N-P-L-L"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-A-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-M-Q-R-L-G-L-P-A-T-R-I-P-L-N-E-R-E-R-I-R-V-D-E-P-Y-I-L-V-V-P-S-Y-G-G-G-G-M-A-G-A-V-P-R-Q-V-I-R-F-L-N-D-E-H-N-R-A-R-I-R-G-V-I-A-S-G-N-R-N-F-G-D-A-W-G-C-A-G-D-V-I-A-Q-K-Y-G-V-P-W-L-Y-R-F-E-L-M-G-T-Q-R-D-I-D-N-V-R-R-G-V-N-E-F-W-Q-Q-L-P-R-S-A"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-T-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-P-P-L-S-P-G-S-R-V-L-I-A-L-I-R-V-Y-Q-R-L-I-S-P-L-L-G-P-H-C-R-F-T-P-T-C-S-S-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-S-W-L-T-V-K-R-V-L-K-C-H-P-L-H-P-G-G-D-D-P-V-P-P-G-P-F-D-T-R-E-H"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-K-T-L-E-E-S-I-D-A-L-M-T-R-Y-K-E-N-V-P-V-R-Y-T-E-Y-V-E-E-W-N-S-P-I-Y-G-T-V-I-D-E-N-T-V-E-W-T-P-C-R-Q-P-E-A-L-N-F-D-D-L-E-S-A-L-E-M-S-F-H-Q-S-I-K-T-L-F-G-R-W-Y-A-G-D-L-A-L-D-Y-Q-G-H-T-I-S-L-L-Q-T-Q-S-A-E-D-G-E-R-L-L-E-N-I-T-G-H-I-L-M-K-R-R-L-K-Q-P-E-T-V-F-I-G-L-G-S-E-D-D-G-L-L-V-T-I-D-N-Q-S-G-A-V-G-L-E-W-V-G-K-E-Q-H-D-V-L-S-D-S-L-A-A-W-L-D-N-C-Q-P-Q-V-E-T-D-K-N-S"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-E-H-F-Q-K-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-E-R-I-F-N-H-I-S-K-D-A-W-A-E-W-Q-K-K-Q-T-M-L-I-N-E-K-R-L-N-M-M-D-P-T-D-R-E-F-L-E-K-Q-M-T-A-F-L-F-E-G-K-A-P-E-I-E-G-Y-T-P-P-E-S"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-L-P-L-K-Q-S-E-E-A-L-K-D-K-R-R-L-R-W-A-C-R-R-G-M-L-E-L-D-V-L-F-E-P-F-V-D-Q-A-Y-D-E-L-S-E-E-Q-K-A-V-F-R-R-L-I-T-C-D-D-P-D-L-F-A-W-F-M-G-H-Q-K-C-E-D-E-E-L-A-E-M-I-R-F-M-L-S-R-V-K-V"} +{"text": "### FUNCTION Substrate-recognition component of the SCF -type E3 ubiquitin ligase complex ### SEQUENCE -M-A-S-W-L-P-E-T-L-F-E-T-V-G-Q-G-P-P-P-S-K-D-Y-Y-Q-L-L-V-T-R-S-Q-V-I-Y-R-W-W-K-I-S-L-R-S-E-Y-R-S-T-K-P-G-E-A-K-E-T-H-E-D-F-L-E-N-S-H-L-Q-G-Q-T-A-L-I-F-G-A-R-I-L-D-Y-V-I-N-L-C-K-G-K-F-D-F-L-E-R-L-S-D-D-L-L-L-N-I-I-S-Y-L-D-L-E-D-I-A-R-L-C-Q-T-S-H-R-F-A-K-L-C-M-S-D-K-L-W-E-Q-I-V-Q-S-T-C-D-T-I-T-P-D-V-R-A-L-A-E-D-T-G-W-R-Q-L-F-F-T-N-K-L-Q-L-Q-R-Q-L-R-K-R-K-Q-K-Y-G-N-L-R-E-K-Q-P"} +{"text": "### FUNCTION May be involved in MAP kinase activation, epithelial sodium channel down-regulation and cell cycling ### SEQUENCE -M-G-T-P-A-S-V-V-S-E-P-P-P-W-Q-A-P-T-E-A-R-G-R-K-Q-A-S-A-N-I-F-Q-D-A-E-L-L-Q-I-Q-G-L-F-Q-R-S-G-D-Q-L-A-E-E-R-A-Q-I-I-W-E-C-A-G-D-H-H-V-A-E-A-L-K-R-L-R-R-K-R-P-P-R-Q-K-P-L-G-H-S-L-H-H-C-S-R-L-R-I-L-E-P-H-S-P-L-A-D-P-Q-S-A-T-E-T-A-S-T-E-Q-Y-L-H-S-R-R-K-S-A-R-I-R-R-N-W-K-K-P-G-P-T-S-Y-L-H-Q-I-R-H"} +{"text": "### FUNCTION May have a potential role in hypercalcemia of malignancy ### SEQUENCE -M-A-Q-G-Q-R-K-F-Q-A-R-K-P-A-K-S-K-T-A-A-T-A-S-E-K-N-R-G-P-R-K-G-G-R-V-I-A-P-K-K-A-R-V-V-Q-Q-Q-K-L-K-K-N-L-E-V-G-I-R-K-K-I-E-H-D-V-V-M-K-A-S-S-S-L-P-K-R-L-A-L-L-K-A-P-A-K-K-K-G-A-A-A-A-T-S-S-K-T-P-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-E-V-L-I-L-L-I-R-F-Y-R-R-F-L-S-P-L-K-P-R-T-C-R-F-H-P-T-C-S-A-Y-A-L-E-A-L-E-R-H-G-A-F-W-G-S-Y-L-A-V-R-R-V-L-R-C-H-P-W-N-P-G-G-L-D-P-V-P-V-L-F-P-P-G-K-V-R-G-G-A-E"} +{"text": "### FUNCTION Additional factor that functions in concert with eIF-2 and the initiator tRNA in directing the ribosome to the proper start site of translation ### SEQUENCE -M-L-N-R-I-I-Y-D-P-F-N-D-G-L-D-T-E-Q-H-F-E-K-I-H-I-K-T-K-Q-R-T-K-T-K-S-I-T-I-I-E-N-I-P-E-K-I-D-L-K-L-F-L-K-K-L-K-Y-T-F-H-C-S-G-S-I-Q-Q-N-Y-D-D-D-S-K-F-I-Q-L-S-G-D-H-R-E-L-V-K-N-F-L-I-K-N-S-I-V-K-E-S-N-I-V-M-H-G-Y"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-L-L-I-Q-I-I-R-L-Y-Q-R-F-I-S-P-L-T-P-P-S-C-R-F-Y-P-T-C-S-A-Y-G-I-E-A-I-E-T-H-G-A-I-K-G-S-Y-L-A-I-K-R-I-L-K-C-H-P-F-H-P-G-G-V-D-P-V-P-E-C-Q-H-T-K-H-K-K-T-P"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-D-K-T-L-R-M-N-Y-L-F-D-F-Y-H-S-L-L-T-E-K-Q-R-N-Y-M-S-Y-Y-Y-L-D-D-L-S-L-G-E-I-A-D-E-Y-D-V-S-R-Q-A-V-Y-D-N-I-R-R-T-E-A-M-L-E-E-Y-E-Q-K-L-R-L-L-E-K-F-E-T-R-R-S-L-L-A-E-L-R-K-A-I-A-S-D-Q-A-V-E-A-C-N-S-L-I-D-R-I-E-K-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-K-I-N-L-M-L-R-Q-I-V-C-L-P-I-K-M-Y-Q-Y-F-I-S-P-L-I-T-P-C-C-R-Y-Y-P-S-C-S-E-Y-A-D-S-A-I-K-H-Y-G-V-I-K-G-L-L-M-A-L-N-R-L-S-R-C-H-P-W-S-K-G-G-Y-D-P-L-F-P-N-D-K-N"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-C-K-L-K-Q-E-A-E-G-L-E-K-Q-P-F-P-G-E-L-G-K-K-V-F-N-E-V-S-K-Q-A-W-N-M-W-L-S-H-Q-T-M-L-I-N-E-Y-R-L-N-L-I-E-A-R-A-R-E-F-L-K-E-E-M-Q-K-Y-F-F-G-E-G-S-D-K-P-S-G-Y-K-E-I-K"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-D-N-R-E-K-S-R-L-L-W-K-C-R-R-G-M-L-E-L-D-L-V-L-Q-K-F-I-A-N-E-I-D-R-L-T-E-N-Q-L-K-A-F-D-N-L-L-T-H-N-D-P-N-L-Y-A-W-L-M-G-H-E-E-P-E-K-E-L-L-E-I-V-S-F-I-R-N-C-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-K-I-S-L-M-L-R-Q-I-V-C-L-P-I-K-M-Y-Q-Y-F-I-S-P-L-I-T-P-C-C-R-Y-Y-P-S-C-S-E-Y-A-D-S-A-I-K-H-Y-G-V-I-K-G-L-L-M-A-L-N-R-L-S-R-C-H-P-W-S-K-G-G-Y-D-P-L-F-P-N-D-K-N"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-C-K-L-K-Q-E-A-E-G-L-E-K-Q-P-F-P-G-E-L-G-K-K-V-F-N-E-V-S-K-Q-A-W-N-M-W-L-S-H-Q-T-M-L-I-N-E-Y-R-L-N-L-I-E-A-R-A-R-E-F-L-K-E-E-M-Q-K-Y-F-F-G-E-G-S-E-K-P-S-G-Y-K-E-I-K"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-D-N-R-E-K-S-R-L-L-W-K-C-R-R-G-M-L-E-L-D-L-L-L-Q-K-F-I-A-N-E-I-D-R-L-T-E-N-Q-L-K-A-F-D-N-L-L-T-H-N-D-P-S-L-Y-A-W-L-M-G-H-E-E-P-E-K-E-L-L-E-I-V-S-F-I-R-N-C-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-N-T-M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-D-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-T-Y-E-M-K-L-H-M-Y-S-D-Y-V-V-R-S-E-I-F-D-D-M-I-A-H-Y-P-H-D-E-Y-L-Q-E-K-I-S-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-A-E-L-I-I-V-Y-F-S-S-K-S-N-N-T-H-R-F-V-Q-K-L-G-L-P-A-Q-R-I-P-V-D-N-R-P-L-E-V-S-T-H-Y-L-L-I-V-P-T-Y-A-A-G-G-S-D-A-K-G-A-V-P-K-Q-V-I-R-F-L-N-N-P-N-N-R-K-H-C-K-G-V-I-S-S-G-N-T-N-F-G-D-T-F-A-L-A-G-P-I-I-S-Q-K-L-Q-V-P-L-L-H-Q-F-E-L-L-G-T-A-T-D-V-K-K-V-Q-A-I-F-A-R-L-K-H-H-T-H-D-K-Q-K-Q-T-N-N-L-I-T-E-R-T-H-P-C-H-K-P-M-R-H-T-S-H"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-S-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-H-L-E-H-E-T-V-A-K-N-P-S-K-Q-R-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-A-G-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-A-E-K-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-S-A-A-A-A-L-H-R-L-P-A-R-A-L-I-F-L-I-E-L-Y-R-T-Y-V-S-P-T-R-M-P-V-C-R-F-T-P-T-C-S-E-Y-A-V-T-A-L-R-T-R-G-L-V-V-G-L-G-L-T-A-V-R-L-A-K-C-A-P-W-H-P-G-G-W-D-P-V-P-Q-R-R-P-R-R-R-D-A-A-A-A-D-A-A-M-S-A-P-H-A-C-K-G-S-P-H-A-V-V-G-D-T-N-D-G-S-T"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-K-I-S-L-M-L-R-Q-I-V-C-L-P-I-K-M-Y-Q-Y-F-I-S-P-L-I-T-P-C-C-R-Y-Y-P-S-C-S-E-Y-A-D-S-A-I-K-H-Y-G-V-I-K-G-L-L-M-A-L-N-R-L-S-R-C-H-P-W-S-K-G-G-Y-D-P-L-F-P-N-D-K-N"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-C-K-L-K-Q-E-A-E-G-L-E-K-Q-P-F-P-G-E-L-G-K-K-V-F-N-E-V-S-K-Q-A-W-N-M-W-L-S-H-Q-T-M-L-I-N-E-Y-R-L-N-L-I-E-A-R-A-R-E-F-L-K-E-E-M-Q-K-Y-F-F-G-E-G-S-E-K-P-S-G-Y-K-E-I-K"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin system ### SEQUENCE -M-R-Y-Q-V-K-F-R-E-D-A-L-K-E-W-Q-K-L-D-K-A-I-Q-Q-Q-F-A-K-K-L-K-K-C-C-D-N-P-H-I-P-S-A-K-L-R-G-I-K-D-C-Y-K-I-K-L-R-A-S-G-F-R-L-V-Y-Q-V-I-D-E-Q-L-I-I-A-V-V-A-V-G-K-R-E-R-S-D-V-Y-N-L-A-S-E-R-M-R"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-S-E-I-I-E-V-I-Y-E-D-G-V-L-K-P-L-K-P-L-K-I-K-G-K-K-R-L-K-I-K-I-V-N-D-D-V-E-E-F-L-K-S-M-I-I-K-K-C-K-D-I-D-Y-K-K-L-K-E-A-Y-Y-E-S-F"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-R-L-L-I-T-L-I-R-L-Y-Q-Y-L-L-S-P-W-L-G-H-H-C-R-F-F-P-T-C-S-N-Y-A-M-D-A-I-G-R-F-G-A-M-R-G-A-Y-L-T-I-R-R-L-M-R-C-H-P-W-H-P-G-G-I-D-P-V-P-E-K-L-G-K-Q"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-L-N-I-N-K-E-I-A-Q-I-E-T-E-L-N-E-L-K-K-L-R-D-E-I-S-E-R-I-E-K-L-E-I-K-L-L-K-L-K-A-L-A-I-P-E-E-E-F-E-E-D-Y-E-E-I-I-E-D-V-K-K-S-L-D-K-K-E-T-V-P-A-E-E-A-L-K-E-L-G-L-L"} +{"text": "### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-K-F-N-V-E-I-H-K-R-V-L-K-D-L-K-D-L-P-P-S-N-L-K-K-F-K-E-L-I-E-T-L-K-T-N-P-I-P-K-E-K-F-D-I-K-R-L-K-G-S-D-E-V-Y-R-V-R-I-G-K-F-R-V-Q-Y-V-V-L-W-D-D-R-I-I-I-I-R-K-I-S-R-R-E-G-A-Y-K-N-P"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-S-Q-R-G-R-L-L-W-S-C-R-R-G-M-A-E-L-D-R-V-L-A-L-Y-V-H-G-A-Y-Q-E-A-D-V-S-E-R-Q-A-F-E-R-L-L-D-L-Q-D-A-D-L-W-R-C-L-T-G-L-A-R-P-E-D-P-A-L-A-A-L-A-A-K-L-R-A-L-V-G-Q-A-A-C"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-R-I-I-C-A-K-L-G-I-E-A-D-G-L-D-A-P-P-F-P-G-P-Q-G-Q-R-I-F-E-H-V-S-K-E-A-W-Q-D-W-L-K-L-Q-T-M-L-I-N-E-H-R-L-T-P-F-E-A-S-A-R-K-F-L-E-Q-E-R-E-K-F-L-F-G-G-G-T-S-T-P-Q-G-Y-V-P-P-R-S"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-H-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-L-Y-E-S-V-S-K-Q-A-W-Q-D-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-A-Q-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-F-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-N-S"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-I-H-C-A-K-L-G-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-L-Y-E-S-V-S-K-Q-A-W-Q-D-W-L-K-Q-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-P-R-A-R-Q-Y-L-M-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-A-Q-G"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-Q-T-V-L-I-A-L-L-R-F-Y-K-L-A-V-S-P-L-L-G-S-R-C-R-F-Y-P-S-C-S-D-Y-A-R-E-A-I-Q-Y-H-G-A-A-R-G-T-Y-L-A-A-R-R-L-C-R-C-H-P-F-S-A-G-G-V-D-L-V-P-P-P-N-S-D-A-R-N-A-P-H-E-A-E-A-S-S-H-R-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-L-L-S-Y-I-L-L-L-P-I-Y-F-Y-R-A-C-I-S-P-M-T-P-P-S-C-R-F-T-P-T-C-S-Q-Y-A-I-E-A-I-K-K-H-G-P-F-K-G-L-Y-L-A-V-R-R-I-L-R-C-H-P-W-G-G-S-G-Y-D-P-V-P"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-G-N-K-E-S-K-Y-L-E-M-C-S-E-E-A-W-L-N-I-P-N-I-F-K-C-I-F-I-R-K-L-F-Y-N-K-W-L-K-Y-Q-E-K-K-L-K-K-S-L-K-L-L-S-F-Y-H-P-K-K-D-F-V-G-I-R-D-M-L-H-M-A-P-G-G-S-Y-F-I-T-D-N-I-T-E-E-F-L-M-L-V-V-K-H-P-E-D-G-S-A-E-F-T-K-L-C-L-K-G-S-C-I-V-I-D-G-Y-Y-Y-D-T-L-H-I-F-L-S-E-T-P-D-I-Y-K-Y-P-L-I-R-Y-D-R"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-G-N-R-L-I-R-S-Y-L-P-N-T-V-M-S-I-E-D-K-Q-N-K-Y-N-E-T-I-E-D-S-K-I-C-N-K-V-Y-I-K-Q-S-G-K-I-D-K-Q-E-L-T-R-I-K-K-L-G-F-F-Y-S-Q-K-S-D-H-E-I-E-R-M-L-F-S-M-P-N-G-T-F-L-L-T-D-D-A-T-N-E-N-I-F-I-V-Q-K-D-L-E-N-G-S-L-N-I-A-K-L-E-F-K-G-K-A-L-Y-I-N-G-K-D-Y-Y-S-L-E-N-Y-L-K-T-F-E-D-F-Y-K-Y-P-L-I-Y-N-K-N-K"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-L-E-R-L-Y-D-A-N-I-Y-N-I-L-S-R-L-R-P-E-K-V-R-N-K-A-I-E-L-Y-W-V-F-R-A-I-H-I-C-H-A-P-L-V-L-D-I-V-R-Y-E-E-P-D-F-A-E-L-A-F-I-C-A-A-Y-F-G-E-P-Q-V-M-Y-L-L-Y-K-Y-M-P-L-T-R-A-V-L-T-D-A-I-Q-I-S-L-E-S-N-N-Q-V-G-I-C-Y-A-Y-L-M-G-G-S-L-K-G-L-V-S-A-P-L-R-K-R-L-R-A-K-L-R-S-Q-R-K-K-K-D-V-L-S-P-H-D-F-L-L-L-L-Q"} +{"text": "### FUNCTION Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing , a mechanism of plant viral defense that performs sequence-specific inhibition of viral mRNAs expression ### SEQUENCE -M-S-M-G-M-V-D-S-L-C-V-F-V-G-R-V-I-T-E-G-S-E-S-V-E-G-V-E-R-F-S-I-K-F-S-D-W-K-L-F-T-T-A-V-Y-V-E-Y-R-Q-L-G-E-K-E-C-S-L-K-D-V-G-R-L-H-F-N-M-S-C-V-K-C-C-Q-K-L-K-C-K-K-Q-N-K-N-H-S-K-H-V-Q-N-G-Y-L-R-K-V-R-N-F-S-I-L-G-V-C-G-D-C-C-E-S-F-T-L-A-D-E-K-H-H-V-I-V-D-P-E-V"} +{"text": "### FUNCTION May form complexes with phosphorylated ligands by interfering with kinases and their effectors ### SEQUENCE -M-A-S-H-V-D-P-L-V-V-G-R-V-I-G-D-V-V-D-L-F-V-P-T-T-A-M-S-V-R-F-G-T-K-D-L-T-N-G-C-E-I-K-P-S-V-A-A-A-P-P-A-V-Q-I-A-G-R-V-N-E-L-F-A-L-V-M-T-D-P-D-A-P-S-P-S-E-P-T-M-R-E-W-L-H-W-L-V-V-N-I-P-G-G-T-D-P-S-Q-G-D-V-V-V-P-Y-M-G-P-R-P-P-V-G-I-H-R-Y-V-M-V-L-F-Q-Q-K-A-R-V-A-A-P-P-P-D-E-D-A-A-R-A-R-F-S-T-R-A-F-A-D-R-H-D-L-G-L-P-V-A-A-L-Y-F-N-A-Q-K-E-P-A-N-R-R-R-R-Y"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-V-F-L-L-L-I-R-F-Y-Q-K-W-I-S-P-A-L-P-P-T-C-R-F-Y-P-T-C-S-N-Y-G-L-E-A-I-E-K-H-G-A-F-K-G-G-W-L-T-I-K-R-I-L-K-C-H-P-F-H-P-G-G-I-D-P-V-P-E-K-K-Q-K-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-A-A-I-I-F-I-R-F-Y-Q-K-A-I-S-P-L-F-P-P-T-C-R-F-Y-P-T-C-S-N-Y-G-L-E-A-I-Q-R-F-G-F-I-K-G-S-Y-L-L-I-K-R-L-L-K-C-H-P-L-H-P-G-G-F-D-P-V-P-N-Q-T-D-Q-K-K-E-G-D-S-D"} +{"text": "### FUNCTION Involved in spore germination ### SEQUENCE -M-F-D-W-Q-R-F-F-P-F-Q-Q-F-S-K-D-G-L-K-N-A-D-P-K-D-V-E-Q-Y-I-H-H-M-M-K-S-V-F-G-P-G-Y-A-V-Q-F-P-F-R-D-P-L-S-K-E-T-S-A-A-D-E-S-D-P-I-D-I-F-E-T-T-S-H-V-F-V-K-I-P-L-T-K-E-Q-L-N-L-L-K-I-K-H-T-S-Q-T-L-I-I-E-N-Y-P-E-K-G-R-Q-E-K-V-V-L-P-S-L-V-R-R-K-G-T-K-A-I-F-K-D-G-I-L-E-V-M-F-L-K-N-E-D-F-N-L-S-E-I-D-I-T-F"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-T-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-T-L-L-T-S-K-Q-K-S-Y-M-S-L-Y-Y-L-D-D-F-S-L-G-E-I-A-E-E-Y-H-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-Q-Y-E-E-K-L-L-L-F-K-K-F-Q-E-R-K-K-I-F-E-A-L-R-K-L-T-D-G-Q-P-E-A-E-S-L-I-D-A-L-E-K-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-T-S-H-S-L-G-E-K-I-L-V-K-L-I-R-F-Y-Q-L-A-I-S-P-M-I-G-P-R-C-R-F-T-P-T-C-S-C-Y-G-I-E-A-I-K-T-H-G-A-L-K-G-S-W-L-T-L-K-R-I-L-K-C-H-P-L-S-K-G-G-Y-D-P-V-P-P-K-I-N-N-N-V-E-K-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-E-Y-L-K-Q-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-R-A-W-G-E-W-M-K-K-Q-T-M-L-V-N-E-K-K-L-N-M-M-N-A-D-H-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-K-D-V-H-I-E-G-Y-I-P-Q-A-T-N"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-D-I-T-D-I-R-I-K-K-V-E-S-K-N-S-G-S-K-L-L-A-Y-V-A-V-T-F-D-N-C-L-V-L-H-N-I-R-V-I-K-G-Q-K-G-V-F-I-A-M-P-N-R-R-T-R-V-G-E-Y-K-D-I-V-H-P-I-S-Q-D-F-R-K-T-L-Q-T-S-I-F-K-E-Y-I-R-E-N-P-A-D-L-E-L-E-L-D-F"} +{"text": "### FUNCTION Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier , a mechanism of plant viral defense that performs sequence-specific inhibition of viral mRNAs expression Silencing activity has been seen in Nicotiana benthamiana and Nicotiana tabacum, two non-host plants ### SEQUENCE -M-C-E-P-P-P-G-F-I-T-V-Q-C-Y-T-S-D-D-L-L-T-G-D-S-T-I-V-K-S-I-P-V-R-S-C-F-F-R-Q-G-V-E-V-V-L-F-R-C-E-S-N-K-H-R-W-S-K-I-R-G-P-V-S-L-T-V-H-C-D-I-C-E-F-R-E-T-V-V-I-P-S-L-P-K-G-F-K-V-S-S-D-F-S-Y-S-V-T-W-N-C-C-Y-S-R-G-R-T-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-P-L-S-P-G-S-R-I-L-I-G-L-I-R-G-Y-Q-L-V-I-S-P-L-L-G-P-R-C-R-F-H-P-T-C-S-H-Y-G-I-E-A-L-R-R-F-G-M-I-K-G-S-W-L-T-L-K-R-V-L-K-C-H-P-L-N-S-G-G-D-D-P-V-P-P-K-L-D-D-N-R-E-H"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-K-K-D-A-E-G-Q-D-F-Q-L-Y-P-G-E-I-G-K-R-I-Y-N-E-I-S-K-E-A-W-S-Q-W-I-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-I-E-D-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-Q-D-V-H-I-A-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-L-N-I-S-T-A-L-R-S-F-T-Q-R-Y-I-D-L-W-Q-Q-Q-T-G-H-L-P-A-S-K-E-L-Y-G-V-P-S-P-C-I-V-E-T-G-E-D-Q-V-F-W-Q-P-Q-A-F-L-P-E-A-T-L-T-N-I-E-R-A-L-E-I-Q-L-H-P-D-I-H-D-F-Y-T-Q-Q-Y-A-G-D-M-M-A-D-L-G-N-H-R-F-T-L-L-Q-V-W-S-E-D-D-F-I-R-L-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-S-P-T-L-F-L-A-T-T-S-S-E-M-T-M-A-S-L-C-N-V-S-G-N-V-V-L-E-Q-F-G-S-D-K-R-T-L-L-A-S-T-L-S-H-F-L-D-A-L-R-P-V-L-P-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-N-P-L-V-Y-F-S-S-S-S-E-N-S-H-R-F-V-E-K-L-Q-L-P-A-I-R-I-P-I-A-G-A-R-E-K-L-R-V-E-Q-P-Y-I-L-L-V-P-S-Y-G-G-G-S-P-V-G-A-V-P-I-Q-V-I-R-F-L-N-D-V-H-N-R-S-L-I-R-G-V-I-A-A-G-N-T-N-F-G-D-A-Y-C-L-A-G-D-I-I-S-H-K-C-Q-V-P-Y-L-Y-R-F-E-L-L-G-T-A-E-D-V-A-N-V-R-K-G-V-T-E-F-W-Q-R-Q-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-R-L-L-M-L-L-V-R-F-Y-Q-R-Y-L-S-P-L-K-G-G-P-T-C-R-F-T-P-S-C-S-Q-Y-A-Y-E-A-L-A-K-Y-G-A-I-K-G-T-W-L-A-V-R-R-V-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-K-D-V-Q-R-I-A-L-L-F-D-F-Y-G-P-L-L-T-E-R-Q-Q-E-L-I-R-A-Y-Y-L-E-D-H-S-L-A-E-I-A-D-A-D-G-V-S-R-Q-A-V-H-E-L-I-R-R-S-E-A-A-L-Q-E-Y-E-Q-R-L-G-F-V-A-E-H-Q-R-R-L-R-L-L-D-E-L-Q-E-A-L-D-R-A-D-L-S-A-A-R-R-A-L-A-A-L-R-A-E-A"} +{"text": "### FUNCTION May be involved in thermogenesis and glucose homeostasis ### SEQUENCE -M-A-A-A-K-K-G-A-K-P-K-V-A-G-V-R-F-A-A-G-F-P-E-E-G-A-H-N-H-V-H-F-D-E-Q-L-H-D-S-V-V-M-V-S-Q-Q-E-D-G-N-F-L-V-K-V-G-F-L-K-I-L-H-K-Y-E-I-S-F-S-L-P-P-V-Q-R-L-G-K-S-I-C-A-V-P-L-P-T-L-N-L-K-V-L-S-I-T-S-Q-A-E-G-H-S-I-K-C-E-Y-T-A-H-K-E-G-V-L-K-E-E-M-I-L-A-S-E-T-N-D-K-A-F-V-K-V-V-V-Q-A-R-V-L-D-R-H-H-G-T-P-M-L-L-E-G-V-R-C-T-G-T-E-L-E-Y-D-S-E-Q-S-D-W-H-G-F-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-K-I-L-L-L-T-I-T-F-Y-K-Y-F-I-S-P-L-L-G-N-N-C-I-F-S-P-T-C-S-E-Y-A-Q-E-A-I-I-T-H-G-I-I-K-G-L-W-L-T-F-R-R-I-I-K-C-Q-P-F-C-I-G-G-Y-D-N-V-P-T-S-I-K-N-S-K-Q-P-T-K-K-I"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-R-G-Y-R-A-V-F-S-P-F-Y-G-D-V-C-R-Y-Y-P-S-C-S-A-Y-T-L-Q-A-V-Q-E-H-G-V-I-F-G-G-Y-L-G-V-C-R-I-L-R-C-H-P-W-A-A-G-G-V-D-D-V-P-L-R-G-K-R-R-Y-R-M-T-A-F-G-F-V-V-A-T-S-Q-G-K-A"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-I-G-N-I-A-Y-I-L-F-T-L-T-V-V-S-A-N-L-F-D-F-I-Q-N-Q-F-Q-G-N-N-Q-Q-A-Q-R-Q-T-P-G-E-Y-E-N-A-N-L-N-S-G-C-S-K-Y-L-C-P-D-T-S-I-C-V-D-E-P-K-F-C-P-C-P-Y-P-S-S-Q-L-R-C-F-L-P-N-G-R-Y-V-C-I-S-K-P-A-G-E-V-S-L-N-Y-A-D-P-K-T-N-W-K-I-D-A-K-D-D-N-I-R-D-C-G-W-V-G-R-A-W-K-G-L-V"} +{"text": "### FUNCTION Involved in ribosome biogenesis, probably through modulation of rDNA transcription ### SEQUENCE -M-S-F-T-S-K-T-S-K-S-H-A-E-A-T-V-N-K-L-F-S-S-L-L-P-G-T-Q-G-T-T-S-K-Q-S-S-S-L-S-S-A-E-L-L-S-I-E-I-E-N-K-N-K-L-S-K-E-E-L-K-K-I-H-K-Q-N-K-F-K-Q-H-K-K-I-K-K-A-L-E-D-E-K-R-F-N-K-L-A-K-Y-H-L-I-K-H-H-K-T-G-G-E-L-S-E-E-E-A-K-Y-L-K-K-L-V-K-K-N-V-N-S-L-N-R-V-S-E-I-D-D-M-E-I-K-S-E-L-D-Q-V-R-Q-D-I-L-K-I-N-K-E-K-H-D-K-K-A-K-R-I-Q-N-K-K-T-K-D-F-N-S-K-V-A-K-G-M-I-S-Y-P-G-L-T-P-G-L-A-P-V-G-L-D-D-S-D-D-E"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-R-P-T-V-I-L-T-C-A-A-A-A-H-A-Q-I-F-G-N-F-F-N-Q-M-L-K-K-E-F-A-V-E-E-S-W-H-N-Q-E-Y-H-K-V-S-C-D-N-G-H-V-C-P-D-T-L-T-C-V-N-S-P-L-E-C-P-C-Q-F-P-A-S-E-I-K-C-V-Y-P-D-K-S-G-Y-V-C-I-S-K-P-G-D-G-Y-D-G-S-D-A-S-S-K-A-E-D-G-K-R-D-C-A-W-V-N-K-A-F-R-G-E-L"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-K-L-L-G-T-I-I-G-S-A-F-F-L-Q-A-V-S-G-F-F-F-D-S-G-H-Q-N-R-Q-Q-Q-Q-Q-Q-Q-Q-Q-R-D-V-G-S-Y-Q-Q-M-F-L-D-N-D-C-P-H-Y-L-C-P-Q-T-L-D-C-V-R-Q-K-S-D-C-A-C-P-F-P-N-S-Q-L-K-C-N-L-P-N-G-Q-V-I-C-I-S-K-P-A-T-H-D-P-T-L-V-E-I-Y-D-D-P-V-M-G-P-A-Q-R-T-E-G-F-R-D-C-G-W-I-L-D-V-Y-D-G-K-I"} +{"text": "### FUNCTION Stimulates the activity of serine palmitoyltransferase ### SEQUENCE -M-A-A-E-K-I-Y-E-P-Y-K-K-S-R-G-T-M-I-Y-T-P-T-N-Q-Q-M-S-R-G-G-I-G-E-K-L-A-D-F-V-K-N-L-Y-W-V-Y-Y-I-H-L-P-F-Y-L-M-T-S-L-D-A-F-C-L-H-T-I-F-L-V-V-V-S-L-S-L-F-G-L-L-K-Y-I-F-L"} +{"text": "### FUNCTION Involved in sporulation and maintenance of the mitochondrial DNA Is probably involved in a pathway contributing to genomic integrity ### SEQUENCE -M-V-L-I-K-S-R-K-S-I-V-T-A-T-N-V-C-I-N-S-S-S-K-F-Y-L-T-E-E-Q-V-Q-S-L-G-D-K-E-F-L-T-A-S-Y-R-R-F-L-R-M-R-Q-F-I-S-K-R-Q-M-V-K-E-S-Y-T-T-Y-L-R-Y-K-F-K-I-E-D-F-E-L-K-R-S-K-L-L-S-V-S-G-M-S-A-M-D-F-R-S-S-V-Q-K-S-L-C-F-L-I-K-A-F-S-I-S-D-A-Y-S-K-D-M-I-D-D-S-H-K-C-K-K-I-I-K-N-L-L-T-V-D-Y-H-R-N-R-I-I-N-R-S-S-N-M-Y-Q-Y-Y-R-K-D-F-T-F-F-T-D-G-Q-N-I-G-L-K-Q-F-E-E-N-L-M-R-L-N-E-C-L-G-T-R-L"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-E-H-E-V-V-S-A-L-A-A-F-T-Q-R-Y-V-A-C-W-Q-Q-E-K-G-H-L-P-A-S-E-A-L-Y-G-I-P-S-P-C-I-V-E-N-H-E-D-T-V-Y-W-S-P-Q-P-F-A-P-S-V-A-L-D-G-V-E-R-A-L-E-I-S-L-H-P-D-V-H-A-F-Y-T-A-Q-Y-A-G-D-M-A-A-Q-F-D-S-L-S-C-Q-L-L-Q-V-W-S-E-E-D-F-T-R-M-Q-E-N-L-I-G-H-L-L-T-Q-K-R-L-K-L-T-P-T-L-F-L-A-T-T-D-S-E-M-T-M-V-S-L-C-N-V-S-G-E-I-V-L-E-A-F-G-T-K-K-R-Q-H-L-A-P-T-L-A-A-F-L-S-G-L-N-P-L-A-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-V-L-Q-R-D-A-E-G-Q-D-F-Q-L-Y-P-G-D-L-G-K-R-I-Y-N-E-I-S-K-E-A-W-A-Q-W-Q-T-K-Q-T-M-L-I-N-E-K-K-L-S-M-M-N-V-D-D-R-K-L-L-E-Q-E-M-I-K-F-L-F-E-G-K-D-V-H-I-E-G-Y-T-P-P-S-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-R-I-L-H-W-L-I-R-F-Y-Q-I-A-I-S-P-M-L-G-P-R-C-R-Y-I-P-T-C-S-Q-Y-S-L-E-A-I-H-T-H-G-A-M-K-G-T-W-L-A-I-H-R-V-C-R-C-H-P-W-G-G-S-G-Y-D-P-V-P-P-K-A-I-R-F-I-S-F-Q-Q-I-D-S-Q-M-L-H-V-T-V-P-F-R-E-R-L-L-N-L-N-H-S-N-H-L-G"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-S-E-E-L-T-L-E-E-R-K-V-I-Y-R-A-R-R-G-L-K-E-I-D-V-Y-F-D-P-Y-V-K-N-Y-Y-L-T-A-P-A-S-E-K-A-L-F-A-E-L-V-A-Q-E-D-P-D-L-L-D-W-F-M-E-V-S-E-P-P-Q-V-E-L-K-Q-L-I-Q-K-L-K-H-Y-V-H-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-L-V-F-C-R-K-Y-Q-Q-E-M-E-G-L-D-F-A-P-F-P-G-A-K-G-Q-E-F-F-D-N-V-S-K-Q-A-W-Q-E-W-L-Q-H-Q-T-T-L-I-N-E-K-R-L-N-V-F-E-P-E-A-K-K-F-L-E-E-Q-R-E-K-F-F-N-N-D-A-S-V-E-K-A-E-G-W-K-P-E-A"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-N-L-L-M-V-L-F-V-A-Q-A-H-A-F-F-F-G-Q-Q-Q-Q-Q-Q-Q-Q-Q-A-S-Y-E-D-R-V-L-D-S-G-C-A-K-Y-L-C-S-D-T-L-E-C-V-D-S-W-K-D-C-P-C-P-F-P-K-S-Q-L-K-C-M-L-P-K-G-S-N-R-P-Y-V-C-I-S-K-P-A-T-H-D-E-K-L-N-L-I-Y-D-D-P-V-Q-G-P-K-A-A-I-K-G-M-R-D-C-G-W-V-Q-Q-N-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-F-K-L-H-P-Q-K-K-K-T-Q-T-R-N-Y-T-G-P-W-R-K-T-P-G-R-L-L-G-L-L-L-I-R-F-Y-Q-I-T-L-S-S-F-I-G-N-Q-C-R-H-A-P-T-C-S-E-Y-I-Y-E-A-I-A-R-H-G-L-W-A-G-A-W-M-G-L-F-R-I-M-R-C-G-P-F-G-T-H-G-F-D-P-V-P-T-S-L-G-N-S-Y-Y-F-Y-K-P-W-C-Y-W-K-I-S-A-R-H-N-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-F-N-P-Y-P-Q-K-K-K-R-Q-T-R-N-Y-T-G-P-W-R-K-T-P-G-R-L-L-G-L-L-L-I-R-F-Y-Q-I-T-L-S-G-F-I-G-N-Q-C-R-H-L-P-T-C-S-E-Y-T-Y-E-A-I-A-R-H-G-L-W-A-G-A-W-M-G-F-F-R-I-I-R-C-G-P-F-G-T-H-G-F-E-P-V-P-T-S-L-G-N-S-Y-C-F-Y-K-P-W-C-Y-W-K-I-S-T-K-H-N-K"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin system Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity ### SEQUENCE -M-L-S-F-S-Q-N-R-S-H-S-L-E-Q-S-L-K-E-G-Y-S-Q-M-A-D-L-N-L-S-L-A-N-E-A-F-P-I-E-C-E-A-C-D-C-N-E-T-Y-L-S-S-N-S-T-N-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Accessory element involved in the expression of sarA and several virulence factors Modulates SarA production and/or function in a strain-dependent manner Affects the transcription of the accessory gene regulator ### SEQUENCE -M-K-Y-L-I-L-S-L-V-A-N-L-L-V-F-G-V-L-S-A-I-G-L-N-I-N-I-L-A-A-M-M-I-V-L-V-I-P-I-M-I-S-G-I-L-F-F-K-T-N-I-D-K-T-Y-I-F-F-N-I-I-F-I-D-F-Y-Y-Y-I-Y-N-V-H-L-M-T-L-P-K-F-N-N-Y-I-K-A-E-M-M-E-L-E-D-I-D-V-L-I-T-S-K-D-F-G-F-D-E-I-L-F-Y-T-L-Y-L-L-L-I-L-I-V-L-Y-Y-L-K-K-Q-V-K-H-K-I"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-Q-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-R-L-F-E-E-S-N-E-D-V-V-E-I-Q-R-A-N-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-A-T-G-Y-I-N-H-L-L-Q-L-I-G-P-S-I-S-Q-Q-Q-A-Y-Y-I-I-D-G-L-L-D-K-M-L-I-N-E-R-E-A-K-M-I-Q-A-V-I-D-R-E-T-L-S-M-D-M-V-S-R-D-I-I-R-A-N-I-L-K-R-L-L-P-V-I-N-Y-Y"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-V-P-D-K-N-A-T-S-E-D-S-E-E-A"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-R-N-E-I-F-E-K-I-M-R-L-E-M-N-V-N-Q-L-S-K-E-T-S-E-L-K-A-L-A-V-E-L-V-E-E-N-V-A-L-Q-L-E-N-D-N-L-K-K-V-L-G-N-D-E-P-T-T-I-D-T-A-N-S-K-P-A-K-A-V-K-K-P-L-P-S-K-D-N-L-A-I-L-Y-G-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-F-C-L-E-V-L-S-D"} +{"text": "### FUNCTION Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host ### SEQUENCE -M-N-Q-H-V-K-V-T-F-D-F-T-N-Y-N-Y-G-T-Y-D-L-A-V-P-A-Y-L-P-I-K-N-L-I-A-L-V-L-D-S-L-D-I-S-I-F-D-V-N-T-Q-I-K-V-M-T-K-G-Q-L-L-V-E-N-D-R-L-I-D-Y-Q-I-A-D-G-D-I-L-K-L-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-F-L-A-M-I-H-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-E-Y-T-R-E-A-I-Q-Y-H-G-A-F-K-G-L-Y-L-G-I-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-S-A-S-K-H-S-H-K-H-N-H"} +{"text": "### FUNCTION Accessory element involved in the expression of sarA and several virulence factors Modulates SarA production and/or function in a strain-dependent manner Affects the transcription of the accessory gene regulator ### SEQUENCE -M-K-Y-L-I-L-S-L-V-A-N-L-L-V-F-G-V-L-S-A-I-G-L-N-I-N-I-L-A-A-M-M-I-V-L-V-I-P-I-M-I-S-G-I-V-F-F-K-T-N-I-D-K-T-Y-I-F-F-N-I-I-F-I-D-F-Y-Y-Y-I-Y-N-V-H-L-M-T-L-P-K-F-N-N-Y-I-K-T-E-M-M-E-L-E-H-I-D-V-L-I-T-S-K-D-F-G-F-D-E-I-L-F-F-T-L-Y-L-L-L-I-L-I-V-L-Y-Y-L-K-K-Q-L-K-N-K-T"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-R-N-Y-L-E-L-F-Y-L-E-D-Y-S-L-S-E-I-A-D-T-F-N-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-K-K-L-E-L-Y-Q-K-F-E-Q-R-R-E-I-Y-D-E-M-K-K-H-L-S-N-P-E-Q-I-Q-R-Y-I-Q-Q-L-E-D-L-E"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-K-I-I-Y-F-S-F-T-G-N-V-R-R-F-I-K-R-T-E-L-E-N-T-L-E-I-T-A-E-N-C-M-E-P-V-H-E-P-F-I-I-V-T-G-T-I-G-F-G-E-V-P-E-P-V-Q-S-F-L-E-V-N-H-Q-Y-I-R-G-V-A-A-S-G-N-R-N-W-G-L-N-F-A-K-A-G-R-T-I-S-E-E-Y-N-V-P-L-L-M-K-F-E-L-H-G-K-N-K-D-V-I-E-F-K-N-K-V-G-N-F-N-E-N-H-G-R-E-K-V-Q-S-Y"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-R-L-F-E-E-S-N-E-D-V-V-E-I-Q-R-A-N-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-A-T-G-Y-I-N-H-L-L-Q-L-I-G-P-S-I-S-Q-Q-Q-A-Y-Y-I-I-D-G-L-L-D-K-M-L-I-N-E-R-E-A-K-M-I-Q-A-V-I-D-R-E-T-L-S-M-D-M-V-S-R-D-I-I-R-A-N-I-L-K-R-L-L-P-V-I-N-Y-Y"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-I-D-E-V-V-P-D-K-N-A-T-S-E-D-S-E-E-A"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-R-N-E-I-F-E-K-I-M-R-L-E-M-N-V-N-Q-L-S-K-E-T-S-E-L-K-A-L-A-V-E-L-V-E-E-N-V-A-L-Q-L-E-N-D-N-L-K-K-V-L-G-N-D-E-P-T-T-I-D-T-A-N-S-K-P-A-K-A-V-K-K-P-L-P-S-K-D-N-L-A-I-L-Y-G-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-F-C-L-E-V-L-S-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-L-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-H-S"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system May function as a regulatory subunit of ion channels ### SEQUENCE -M-A-A-V-A-A-A-S-A-E-L-L-I-I-G-W-Y-I-F-R-V-L-L-Q-V-F-L-E-C-C-I-Y-W-V-G-F-A-F-R-N-P-P-G-T-Q-P-I-A-R-S-E-V-F-R-Y-S-L-Q-K-L-A-H-T-V-S-R-T-G-R-Q-V-L-G-E-R-R-Q-R-A-P-N"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-T-R-L-K-K-D-A-E-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-I-S-K-E-A-W-A-E-W-Q-S-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-H-R-K-L-L-E-T-E-M-V-N-F-L-F-E-G-Q-D-V-I-I-E-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-Y-M-L-S-S-D-E-R-A-R-L-K-W-A-C-R-R-G-M-L-E-L-D-V-I-I-M-P-F-F-E-E-C-L-D-D-L-P-D-Q-E-Q-R-D-F-V-S-L-L-T-S-D-D-P-D-L-F-T-W-M-M-G-H-G-R-S-E-N-P-A-H-A-A-M-V-D-K-I-V-A-H-N-N-S-K-L-R"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-I-I-T-T-S-R-K-P-S-Q-R-T-R-S-L-V-N-D-L-A-R-V-F-N-F-K-I-L-N-R-G-K-I-P-L-S-E-L-I-E-N-K-D-D-M-I-I-V-E-E-L-K-G-N-P-G-R-L-K-I-F-N-F-E-N-N-K-I-L-S-M-N-L-S-L-K-L-Q-R-E-V-S-G-K-A-F-K-N-S-G-K-L-G-S-K-F-D-K-N-T-E-H-L-K-E-F-F-F-E-Y-L-F-K-K-L-S-N-Y-K-E-E-N-F-E-V-V-I-T-F-K-T-V-D-E-S-T-F-Y-I-E-V-H-K-G-S-E-N-M-G-P-S-L-K-I-K-T-V-K-I-L-D-I-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-K-K-L-L-I-Y-F-V-R-F-Y-Q-Y-T-L-S-P-L-L-G-L-T-C-R-F-Y-P-T-C-S-E-Y-M-I-L-A-L-Q-K-H-G-A-M-K-G-A-Y-L-G-V-K-R-I-C-R-C-H-P-W-N-P-G-G-H-D-P-V-P-E-S-T-I-L-S-K-E-K-S-V-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-E-V-K-V-F-P-V-N-E-D-R-L-K-A-Y-V-S-I-T-L-D-N-C-F-V-V-R-D-L-K-V-I-Q-G-T-S-G-L-F-V-A-M-P-S-K-K-R-K-D-G-Q-F-R-D-I-A-H-P-L-N-Q-E-T-R-A-M-I-E-D-L-I-F-E-A-Y-E-K-E-L-K-S-M-G-E-T-L-V-S-L-K-R-Q-K-A-P-G-S-D-Y-G-N-D-D-Y"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-S-A-S-F-D-R-Y-V-S-F-Q-H-C-D-W-E-G-R-S-E-R-V-M-Q-R-L-Q-R-H-V-E-A-A-E-N-P-F-W-A-Y-F-A-Q-K-R-A-E-L-R-D-K-Q-G-L-D-D-L-R-I-L-H-N-Y-L-P-T-L-R-E-L-L-E-D-N-G-D-L-E-T-L-E-M-L-E-D-L-E-A-N-L-M"} +{"text": "### FUNCTION May act as an apoptosis inhibitor ### SEQUENCE -M-D-I-V-P-I-S-P-Y-E-R-M-R-P-L-R-E-S-K-E-L-R-I-K-S-F-D-D-H-R-W-P-H-K-N-N-P-V-M-T-K-N-M-I-E-N-Y-F-Y-Y-I-G-I-N-D-K-I-Q-C-V-H-C-G-G-V-I-S-G-F-L-E-E-D-T-H-R-I-S-Y-E-H-R-R-H-F-P-K-C-P-V-G-K-Y-R-H-P-G-Y-H-L-D-A-E-R-L-K-S-F-K-N-W-R-Y-E-N-I-V-R-K-M-D-L-V-A-A-G-L-F-Y-T-G-I-E-D-R-C-A-C-H-Q-C-G-N-E-L-Y-E-W-E-A-G-D-N-P-K-E-E-H-K-R-L-F-P-D-C-K-L-S-S-Y"} +{"text": "### FUNCTION Virion protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-Q-G-C-D-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-Y-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V"} +{"text": "### FUNCTION More likely to influence phosphoinositide metabolism than actin assembly ### SEQUENCE -M-A-E-W-H-K-I-I-E-D-I-S-K-N-N-K-F-E-D-A-A-I-V-D-Y-K-T-T-K-N-V-L-A-A-I-P-N-R-T-F-A-K-I-N-P-G-E-I-I-P-L-I-T-N-R-N-I-L-K-P-L-I-G-Q-K-Y-C-I-V-Y-T-N-S-L-M-D-E-N-T-Y-A-M-E-L-L-T-G-Y-A-P-V-S-P-I-V-I-A-R-T-H-T-A-L-I-F-L-M-G-K-P-T-T-S-R-R-D-V-Y-R-T-C-R-D-H-A-T-R-V-R-A-T-G-N"} +{"text": "### FUNCTION May play a role in rearrangement of cellular cytoskeleton towards an efficient viral assembly and spreading ### SEQUENCE -M-F-L-G-Y-S-D-C-V-D-P-G-L-A-V-Y-R-V-S-R-S-R-L-K-L-M-L-S-F-V-W-L-V-G-L-R-F-H-D-C-A-A-F-E-S-C-C-Y-D-I-T-E-A-E-S-N-K-A-I-S-R-D-E-A-A-F-T-S-S-V-S-T-R-T-P-S-L-A-I-A-P-P-P-D-R-S-M-L-L-S-R-E-E-E-L-V-P-W-S-R-L-I-I-T-K-Q-F-Y-G-G-L-I-F-H-T-T-W-V-T-G-F-V-L-L-G-L-L-T-L-F-A-S-L-F-R-V-P-Q-S-I-C-R-F-C-I-D-R-L-R-D-I-A-R-P-L-K-Y-R-Y-Q-R-L-V-A-T-V"} +{"text": "### FUNCTION Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion Required for meiosis, but plays no role in conjugation ### SEQUENCE -M-S-A-E-D-L-F-T-I-Q-I-L-C-D-Q-I-E-L-K-L-A-S-I-V-I-N-S-N-I-K-L-Q-L-K-R-K-K-K-T-Q-Q-L"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-K-I-R-K-I-N-G-E-S-R-L-R-G-V-S-S-I-T-F-E-N-Q-F-V-V-N-D-I-R-I-I-E-G-E-R-G-I-F-I-A-M-P-S-R-K-T-S-K-G-N-F-R-D-I-A-H-P-I-N-S-E-T-R-Q-L-I-E-N-C-I-K-T-K-Y-Q-D-L-L-D-N-P-P-Q-E-E-D-F-S-Q-N-S-E-N"} +{"text": "### FUNCTION Involved in pollen development ### SEQUENCE -M-A-R-F-L-V-A-L-L-A-A-T-L-V-A-V-Q-A-G-G-Q-L-G-H-A-A-P-A-T-A-E-V-F-W-R-A-V-L-P-H-S-P-L-P-D-A-V-L-R-L-L-K-Q-P-A-A-G-V-E-L-H-T-E-A-T-S-F-V-R-D-P-E-D-R-P-P-F-D-Y-R-D-Y"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-F-E-K-T-N-R-M-N-L-L-F-D-F-Y-Q-E-L-L-T-T-K-Q-K-A-Y-V-S-F-Y-Y-L-D-D-Y-S-L-G-E-I-A-E-E-F-E-V-S-R-Q-A-I-Y-D-N-I-K-R-T-E-E-S-L-E-K-Y-E-E-K-L-G-M-L-K-K-Y-Q-Q-R-E-K-L-F-S-Q-L-E-A-Q-L-T-K-K-N-F-L-D-E-Q-V-K-D-T-L-E-Q-L-K-N-I-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-A-I-F-D-S-V-S-N-M-E-E-Q-I-G-E-L-Y-Q-Q-L-G-D-L-K-T-N-L-G-E-M-L-E-E-N-N-R-L-N-L-E-N-E-H-L-R-R-R-L-S-L-T-D-E-A-T-P-E-P-K-A-E-I-E-A-E-H-G-V-M-A-P-N-R-K-E-A-M-Q-Q-M-I-E-L-G-E-G-Y-D-N-L-V-Q-L-Y-K-E-G-F-H-V-C-N-V-H-F-G-S-P-R-G-N-D-E-D-C-L-F-C-L-S-L-L-N-K-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-E-V-L-I-L-L-I-R-F-Y-R-R-F-L-S-P-L-K-P-R-T-C-R-F-H-P-T-C-S-A-Y-A-L-E-A-L-E-R-H-G-A-F-W-G-S-Y-L-A-V-R-R-V-L-R-C-H-P-W-N-P-G-G-L-D-P-V-P-V-L-F-P-P-G-K-V-R-G-G-A-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-R-F-V-I-Q-L-I-Q-L-Y-K-R-L-L-S-P-L-L-P-P-A-C-R-F-T-P-T-C-S-E-Y-A-A-Q-A-F-Q-E-Y-G-F-F-R-A-L-Q-L-S-I-W-R-I-L-R-C-N-P-L-S-R-G-F-D-D-P-L-P-P-N-T-K-G"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-P-F-S-Q-L-S-Q-L-Q-H-N-L-Q-A-M-T-K-T-V-A-G-L-E-N-D-M-L-E-V-L-K-E-N-T-E-L-K-V-E-N-Q-L-L-R-E-K-I-S-K-L-D-A-N-K-E-P-A-E-N-K-S-Q-A-G-L-K-S-L-R-N-I-Y-D-S-G-Y-H-I-C-N-M-Y-Y-G-S-H-R-E-S-G-E-D-C-M-F-C-L-D-I-L-D-N-F-V-N-H-G-Q-K-S-R-G"} +{"text": "### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-Q-I-I-P-E-S-P-E-V-D-L-D-K-L-L-E-K-V-K-E-V-I-K-D-Y-G-E-Y-Y-K-H-E-V-E-P-L-A-F-G-L-K-S-L-I-V-Y-F-L-I-P-E-T-S-F-N-E-E-Q-F-L-D-N-I-K-Q-I-E-E-V-S-D-A-E-I-L-M-A-T-R-A"} +{"text": "### FUNCTION Probable component of the endoplasmic reticulum-associated degradation pathway ### SEQUENCE -M-I-A-H-L-I-V-A-L-L-A-M-P-V-Q-S-F-F-F-D-F-G-G-H-Q-A-Q-Q-Q-T-Q-Q-T-T-S-Y-E-D-S-V-L-N-S-D-C-K-G-Y-V-C-P-Y-T-N-E-C-S-R-G-P-E-E-C-S-C-P-F-P-R-S-Q-L-R-C-V-L-P-N-K-Q-V-V-C-I-S-K-P-A-T-N-D-K-K-L-N-D-V-Y-D-D-T-A-K-G-P-R-A-R-N-K-G-V-R-D-C-G-W-V-E-A-A-Y-K-G-L-V"} +{"text": "### FUNCTION More likely to influence phosphoinositide metabolism than actin assembly ### SEQUENCE -M-V-E-W-H-K-I-I-E-D-I-S-K-N-N-K-F-E-D-A-A-I-V-D-Y-K-T-T-K-N-V-L-A-A-I-P-N-R-T-F-A-K-I-N-P-G-E-V-I-P-L-I-T-N-H-N-I-L-K-P-L-I-G-Q-K-F-C-I-V-Y-T-N-S-L-M-D-E-N-T-Y-A-M-E-L-L-T-G-Y-A-P-V-S-P-I-V-I-A-R-T-H-T-A-L-I-F-L-M-G-K-P-T-T-S-R-R-D-V-Y-R-T-C-R-D-H-A-T-R-V-R-A-T-G-N"} +{"text": "### FUNCTION More likely to influence phosphoinositide metabolism than actin assembly ### SEQUENCE -M-A-E-W-H-K-I-I-E-D-I-S-K-N-N-K-F-E-D-A-A-I-V-D-Y-K-T-T-K-N-V-L-A-A-I-P-N-R-T-F-A-K-I-N-P-G-E-I-I-P-L-I-T-N-R-N-I-L-K-P-L-I-G-Q-K-Y-C-I-V-Y-T-N-S-L-M-D-E-N-T-Y-A-M-E-L-L-T-G-Y-A-P-V-S-P-I-V-I-A-R-T-H-T-A-L-I-F-L-M-G-K-P-T-T-S-R-R-D-V-Y-R-T-C-R-D-H-A-T-R-V-R-A-T-G-N"} +{"text": "### FUNCTION May be involved in the regulation of ssDNA versus dsDNA levels ### SEQUENCE -M-G-P-F-R-V-D-Q-F-P-D-N-Y-P-A-F-L-A-V-S-T-S-C-F-L-R-Y-N-R-W-C-I-L-G-I-H-Q-E-I-G-S-L-T-L-E-E-G-E-V-F-R-Q-F-Q-K-E-V-K-K-L-L-R-C-K-V-N-F-H-R-K-C-S-L-Y-E-E-I-Y-K-K-Y-V-Y-N-V-P-E-K-K-G-E-S-S-K-C-V-A-E-E-E-E-D"} +{"text": "### FUNCTION More likely to influence phosphoinositide metabolism than actin assembly ### SEQUENCE -M-A-E-W-H-K-I-I-E-D-I-S-K-N-N-K-F-E-D-A-A-I-V-D-Y-K-T-T-K-N-V-L-A-A-I-P-N-R-T-F-A-K-I-N-P-G-E-I-I-P-L-I-T-N-R-N-I-L-K-P-L-I-G-Q-K-Y-C-I-V-Y-T-N-S-L-M-D-E-N-T-Y-A-M-E-L-L-T-G-Y-A-P-V-S-P-I-V-I-A-R-T-H-T-A-L-I-F-L-M-G-K-P-T-T-S-R-R-D-V-Y-R-T-C-R-D-H-A-T-R-V-R-A-T-G-N"} +{"text": "### FUNCTION Accessory element involved in the expression of sarA and several virulence factors Modulates SarA production and/or function in a strain-dependent manner Affects the transcription of the accessory gene regulator ### SEQUENCE -M-K-Y-L-I-L-S-L-V-A-N-L-L-V-F-G-V-L-S-A-I-G-L-N-I-N-I-L-A-A-M-M-I-V-L-V-I-P-I-M-I-S-G-I-L-F-F-K-T-N-I-D-K-T-Y-I-F-F-N-I-I-F-I-D-F-Y-Y-Y-I-Y-N-V-H-L-M-T-L-P-K-F-N-N-Y-I-K-A-E-M-M-E-L-E-D-I-D-V-L-I-T-S-K-D-F-G-F-D-E-I-L-F-Y-T-L-Y-L-L-L-I-L-I-V-L-Y-Y-L-K-K-Q-V-K-H-K-I"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-R-L-F-E-E-S-N-E-D-V-V-E-I-Q-R-A-N-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-A-T-G-Y-I-N-H-L-L-Q-L-I-G-P-S-I-S-Q-Q-Q-A-Y-Y-I-I-D-G-L-L-D-K-M-L-I-N-E-R-E-A-K-M-I-Q-A-V-I-D-R-E-T-L-S-M-D-M-V-S-R-D-I-I-R-A-N-I-L-K-R-L-L-P-V-I-N-Y-Y"} +{"text": "### FUNCTION Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host ### SEQUENCE -M-N-Q-H-V-K-V-T-F-D-F-T-N-Y-N-Y-G-T-Y-D-L-A-V-P-A-Y-L-P-I-K-N-L-I-A-L-V-L-D-S-L-D-I-S-I-F-D-V-N-T-Q-I-K-V-M-T-K-G-Q-L-L-V-E-N-D-R-L-I-D-Y-Q-I-A-D-G-D-I-L-K-L-L"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-R-L-F-E-E-S-N-E-D-V-V-E-I-Q-R-A-N-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-A-T-G-Y-I-N-H-L-L-Q-L-I-G-P-S-I-S-Q-Q-Q-A-Y-Y-I-I-D-G-L-L-D-K-M-L-I-N-E-R-E-A-K-M-I-Q-A-V-I-D-R-E-T-L-S-M-D-M-V-S-R-D-I-I-R-A-N-I-L-K-R-L-L-P-V-I-N-Y-Y"} +{"text": "### FUNCTION Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host ### SEQUENCE -M-N-Q-H-V-K-V-T-F-D-F-T-N-Y-N-Y-G-T-Y-D-L-A-V-P-A-Y-L-P-I-K-N-L-I-A-L-V-L-D-S-L-D-I-S-I-F-D-V-N-T-Q-I-K-V-M-T-K-G-Q-L-L-V-E-N-D-R-L-I-D-Y-Q-I-A-D-G-D-I-L-K-L-L"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-V-T-D-V-R-L-R-R-V-E-T-D-G-R-M-R-A-I-A-S-I-T-L-D-E-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-G-V-D-G-E-F-R-D-I-A-H-P-I-N-S-D-T-R-A-K-I-Q-E-V-V-L-A-E-Y-E-R-V-G-E-E-E-A-T-A-V-T-E-E-E-S-E-S-V-S-A-E"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Chaperone component of an atypical, type II toxin-antitoxin chaperone module, probably required for antitoxin HigA1 to neutralize its cognate toxin HigB1 ### SEQUENCE -M-T-D-R-T-D-A-D-D-L-D-L-Q-R-V-G-A-R-L-A-A-R-A-Q-I-R-D-I-R-L-L-R-T-Q-A-A-V-H-R-A-P-K-P-A-Q-G-L-T-Y-D-L-E-F-E-P-A-V-D-A-D-P-A-T-I-S-A-F-V-V-R-I-S-C-H-L-R-I-Q-N-Q-A-A-D-N-D-V-K-E-G-D-T-K-D-E-T-Q-D-V-A-T-A-D-F-E-F-A-A-L-F-D-Y-H-L-Q-E-G-E-D-D-P-T-E-E-E-L-T-A-Y-A-A-T-T-G-R-F-A-L-Y-P-Y-I-R-E-Y-V-Y-D-L-T-G-R-L-A-L-P-P-L-T-L-E-I-L-S-R-P-M-P-V-S-P-G-A-Q-W-P-A-T-R-G-T-P"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-S-Q-L-T-Y-L-F-R-T-A-P-H-S-H-S-S-G-R-E-G-V-D-A-L-L-A-A-S-A-Y-C-E-A-L-S-V-V-F-I-G-D-G-V-Y-Q-L-L-A-G-Q-Q-T-A-S-I-L-C-K-D-Y-A-P-M-F-K-L-F-D-L-Y-D-I-E-H-V-Y-V-C-Q-Q-S-L-Q-Q-R-G-L-T-S-E-D-L-L-I-D-V-E-V-V-D-T-V-R-L-Q-G-V-L-H-N-S-A-Q-L-L-S-F"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-A-R-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-D-P-E-H-R-K-L-L-E-T-E-M-V-N-F-L-F-E-G-K-E-V-H-I-E-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-Y-T-T-E-E-K-A-R-I-R-W-A-C-R-R-G-M-L-E-L-D-V-V-V-M-P-F-F-E-E-C-F-D-K-L-S-E-Q-E-Q-R-D-F-V-S-L-L-E-C-D-D-P-D-L-F-T-W-V-M-G-H-G-R-S-E-N-L-G-H-A-S-M-V-D-K-I-V-A-H-N-L-S-K-V-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-T-L-L-I-G-M-I-W-V-Y-Q-K-V-I-S-P-L-K-R-P-T-C-R-Y-Y-P-S-C-S-E-Y-A-L-W-L-F-S-Y-S-N-F-W-Y-A-L-L-F-S-L-R-R-I-L-R-C-N-S-L-F-E-G-G-I-D-Y-P-I-I-S-K-R-I-T-P-I-F-G-S-P-R-L-I-K-V-W-L-V-P-L-C-P-Q-K-D-W-S-A-K-G-K-F-Y-L-I-K-S-M-K-V-V-Q-C"} +{"text": "### FUNCTION Is required to sustain N fixation ability of the nitrogenase complex, which is inactivated in the presence of CO ### SEQUENCE -M-S-S-I-F-I-N-K-G-V-E-M-M-E-S-E-K-S-G-G-M-D-R-Y-V-T-F-E-R-I-D-C-F-K-N-A-H-E-V-V-S-N-A-L-R-V-L-E-A-N-P-E-M-K-N-P-F-W-E-K-F-C-S-K-I-P-D-S-F-Y-S-Y-T-P-Q-E-D-L-L-Y-L-V-C-A-N-V-F-Y-L-E-E-L-F-D-E-A-E-D-E-E-G-Q-A-I-M-S-R-C-E-F-E-C-C"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-L-I-K-A-F-L-V-Q-L-L-L-L-P-I-F-F-Y-K-R-F-I-S-P-L-T-P-P-S-C-R-F-T-P-S-C-S-S-Y-A-I-E-A-L-R-K-Y-G-P-G-K-G-L-L-L-S-I-K-R-I-L-R-C-H-P-W-G-G-S-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-S-S-L-S-F-G-S-R-F-L-I-A-L-I-R-G-Y-Q-L-V-I-S-P-L-L-G-P-R-C-R-F-N-P-T-C-S-Q-Y-G-I-E-A-L-R-R-F-G-V-I-K-G-C-W-L-T-V-K-R-V-L-K-C-H-P-L-H-E-G-G-D-D-P-V-P-P-V-K-N-N-D-N-R-E-H"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-N-I-N-P-L-I-Y-F-S-S-S-S-S-N-S-H-R-F-V-Q-K-L-E-I-P-A-F-R-I-P-I-N-Q-S-D-S-P-L-N-I-T-S-P-Y-I-L-L-T-P-S-Y-G-G-G-S-T-K-G-A-V-P-P-Q-V-I-R-F-L-N-I-A-E-N-R-A-F-I-R-G-V-I-A-A-G-N-T-N-F-G-E-A-Y-G-I-A-G-R-I-I-S-E-K-C-R-I-P-L-L-Y-R-F-E-L-L-G-T-E-E-D-V-Q-R-V-R-Q-G-I-Q-R-F-W-Q-H-D-S-L-E-N-M"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-N-R-T-V-F-C-T-F-L-Q-R-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-N-E-I-S-K-E-A-W-R-Q-W-M-S-K-Q-T-M-L-I-N-E-K-K-L-S-T-M-N-P-E-D-R-K-L-L-E-Q-E-M-T-K-F-L-F-E-G-H-D-I-Q-I-D-G-Y-T-P-P-E-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-E-L-V-R-R-A-A-T-G-A-I-R-F-Y-Q-R-F-V-S-P-L-T-P-P-T-C-R-Y-V-P-T-C-S-E-Y-T-R-Q-A-I-E-R-F-G-V-A-A-G-I-W-L-G-T-K-R-L-C-R-C-H-P-L-H-P-G-G-Y-D-P-V-P-E-R-R-S-V-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-R-I-L-I-L-L-I-R-F-Y-Q-L-A-I-S-P-W-L-A-P-R-C-R-F-Q-P-T-C-S-G-Y-A-I-E-A-V-S-K-H-G-A-L-K-G-G-C-L-A-A-R-R-I-C-R-C-H-P-W-G-G-S-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-N-C-I-K-L-G-R-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-R-V-Y-E-S-V-S-K-E-A-W-Q-G-W-L-R-Y-Q-T-M-L-I-N-E-N-R-L-S-L-A-D-A-R-A-R-Q-Y-L-A-S-Q-L-D-A-Y-F-F-G-Q-G-A-D-A-P-A-G-Y-T-P-P-Q-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-A-G-I-G-F-Y-R-R-F-I-S-P-L-I-G-P-R-C-R-F-T-P-T-C-S-A-Y-G-L-E-A-I-Q-R-H-G-P-W-K-G-G-W-L-T-V-K-R-L-L-R-C-H-P-F-T-P-C-G-C-D-P-V-P-D"} +{"text": "### FUNCTION Major determinant of cell surface composition Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides ### SEQUENCE -M-E-H-S-L-N-S-L-N-N-F-D-F-L-A-R-S-F-A-R-M-H-A-E-G-R-P-V-D-I-L-A-V-T-G-N-M-D-E-E-H-R-T-W-F-C-A-R-Y-A-W-Y-C-Q-Q-M-M-Q-A-R-E-L-E-L-E-H"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-F-K-T-I-N-K-S-I-T-S-I-L-L-F-M-I-S-C-Y-Q-K-W-F-S-P-F-F-G-P-R-C-R-F-I-P-S-C-S-S-Y-G-Y-E-A-I-T-R-H-G-P-W-K-G-G-W-L-T-L-R-R-L-S-R-C-H-P-L-T-P-C-G-C-D-P-V-P-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-E-S-N-T-L-S-G-G-I-F-A-L-L-N-R-A-I-G-S-V-L-L-A-L-I-G-F-Y-R-T-W-L-S-P-L-L-G-P-H-C-R-F-I-P-S-C-S-A-Y-G-L-E-A-I-Q-R-H-G-P-W-R-G-G-W-L-T-L-R-R-L-S-R-C-H-P-F-T-P-C-G-C-D-P-V-P-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-K-K-I-N-A-V-I-S-N-L-F-L-T-L-I-R-F-Y-R-S-W-I-S-P-L-L-G-P-S-C-R-F-V-P-T-C-S-E-Y-G-V-E-A-I-E-K-H-G-P-W-K-G-G-W-L-T-L-K-R-L-L-R-C-N-P-L-T-P-C-G-Y-D-P-V-P-D-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-F-C-E-Y-L-K-K-E-A-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-N-S-I-S-K-Q-A-W-A-E-W-I-K-K-Q-T-M-L-V-N-E-K-K-L-N-M-M-N-P-E-H-R-Q-L-L-E-A-E-M-V-N-F-L-F-E-G-K-D-V-H-I-D-G-Y-V-P-V-Q-T-N-T-K-A"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-A-E-L-N-R-F-K-I-E-W-Q-C-R-R-G-M-R-E-L-D-K-M-I-M-P-F-Y-Q-Q-Y-F-E-Q-L-S-E-A-E-Q-R-T-F-V-T-M-L-S-Y-T-D-P-E-L-F-R-W-V-M-H-Q-S-P-A-P-T-V-A-I-S-A-L-I-E-R-I-R-A-S-I-E-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-V-S-L-P-K-L-S-A-K-I-I-I-R-L-I-Y-I-Y-Q-I-G-I-S-P-I-L-G-H-H-C-R-F-S-I-T-C-S-Q-Y-G-I-N-S-I-R-N-F-G-I-L-K-G-C-W-K-T-C-I-R-I-L-K-C-H-P-F-N-K-N-D-N-T-Q"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-K-I-I-Y-C-I-Y-L-K-K-Y-A-E-G-L-K-F-P-C-Y-P-G-K-L-G-E-Y-I-Y-K-N-I-S-Q-E-A-W-N-K-W-Q-N-V-Q-T-I-L-I-N-E-N-K-L-N-M-L-C-A-K-D-R-S-I-I-E-K-K-M-K-K-F-L-C-L-K-P-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-R-R-L-L-I-A-P-I-R-F-Y-R-Y-F-L-S-P-W-V-G-R-Q-C-R-F-T-P-T-C-S-A-Y-A-I-E-A-I-E-R-H-G-A-W-R-G-L-W-L-A-A-R-R-I-G-R-C-H-P-W-S-P-G-G-Y-D-P-V-P-P-G-H-G-A-G-A-Q-A-C-C-A-H-R-H-R-T-E-P-D"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-I-V-N-C-V-K-L-K-R-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-T-R-I-W-Q-Q-I-S-K-E-A-W-E-E-W-K-Q-I-Q-T-R-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-K-Y-L-Q-Q-Q-M-E-R-F-L-F-E-D-G-T-V-E-A-Q-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-R-R-L-L-I-A-P-I-R-F-Y-R-Y-F-L-S-P-W-V-G-R-Q-C-R-F-T-P-T-C-S-A-Y-A-I-E-A-I-E-R-H-G-A-W-R-G-L-W-L-A-A-R-R-I-G-R-C-H-P-W-S-P-G-G-Y-D-P-V-P-P-G-H-G-A-G-A-Q-A-C-C-A-H-R-H-R-T-E-P-D"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-I-V-N-C-V-K-L-K-R-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-T-R-I-W-Q-Q-I-S-K-E-A-W-E-E-W-K-Q-I-Q-T-R-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-K-Y-L-Q-Q-Q-M-E-R-F-L-F-E-D-G-T-V-E-A-Q-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-R-R-L-L-I-A-P-I-R-F-Y-R-Y-F-L-S-P-W-V-G-R-Q-C-R-F-T-P-T-C-S-A-Y-A-I-E-A-I-E-R-H-G-A-W-R-G-L-W-L-A-A-R-R-I-G-R-C-H-P-W-S-P-G-G-Y-D-P-V-P-P-G-H-G-A-G-A-Q-A-C-C-A-H-R-H-R-T-E-P-D"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-I-V-N-C-V-K-L-K-R-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-T-R-I-W-Q-Q-I-S-K-E-A-W-E-E-W-K-Q-I-Q-T-R-L-V-N-E-N-R-L-N-L-A-D-A-R-A-R-K-Y-L-Q-Q-Q-M-E-R-F-L-F-E-D-G-T-V-E-A-Q-G-Y-V-P-P-S-A"} +{"text": "### FUNCTION The protein is truncated in this strain and presumably inactive It has similarities with variola virus CrmB, but the product is inactivated due to several premature stop codon ### SEQUENCE -M-W-K-L-I-C-I-Q-L-T-T-T-T-G-L-S-E-S-I-S-T-S-E-L-T-I-T-M-N-H-K-D-C-N-P-V-F-R-E-E-Y-F-S-V-L-N-K-V-A-T-S-G-F-F-T-G-E-R-C-A-L"} +{"text": "### FUNCTION More likely to influence phosphoinositide metabolism than actin assembly ### SEQUENCE -M-A-E-W-H-K-I-I-E-D-I-S-K-N-N-K-F-E-D-A-A-I-V-D-Y-K-T-T-K-N-V-L-A-A-I-P-N-R-T-F-A-K-I-N-P-G-E-V-I-P-L-I-T-N-H-N-I-L-K-P-L-I-G-Q-K-F-C-I-V-Y-T-N-S-L-M-D-E-N-T-Y-A-M-E-L-L-T-G-Y-A-P-V-S-P-I-V-I-A-R-T-H-T-A-L-I-F-L-M-G-K-P-T-T-S-R-R-D-V-Y-R-T-C-R-D-H-A-T-R-V-R-A-T-G-N"} +{"text": "### FUNCTION Involved in late/very late gene activation ### SEQUENCE -M-S-K-K-E-N-I-I-G-N-K-N-R-T-Q-K-Y-N-N-A-C-L-T-R-S-D-V-Y-A-L-V-K-E-T-I-N-K-R-K-H-D-G-E-F-C-N-I-T-A-H-I-F-D-E-G-F-E-Q-Q-K-E-Y-I-R-E-K-L-S-T-A-S-I-V-T-D-C-R-Q-N-R-K-R-L-A-L-H-R-K-K-I-E-S-I-F-N-I-H-T-S-L-Q-E-E-F-N-S-C-S-R-R-Y-N-G-S-P-N-L-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-L-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-N-S"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-G-I-I-R-F-Y-Q-K-F-I-S-P-M-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-L-E-A-F-Q-K-H-G-A-F-K-G-F-W-L-T-C-K-R-I-L-K-C-H-P-F-H-P-G-G-F-D-P-V-P-D-K-K-D-D-K-V-N-S"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-E-K-T-T-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-Q-K-Q-R-S-Y-M-S-L-Y-Y-L-D-D-L-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-V-L-L-Q-K-F-Q-E-R-Q-R-L-V-A-K-L-K-Q-L-I-S-E-E-E-H-V-N-E-E-M-K-Q-V-V-E-A-I-E-K-L-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-F-K-L-F-I-K-N-L-P-T-N-L-C-C-G-L-I-H-I-Y-R-W-T-I-S-P-L-L-G-S-P-C-R-F-F-P-T-C-S-Q-Y-A-L-Q-A-L-K-H-H-G-C-I-K-G-L-G-L-T-I-K-R-I-G-K-C-G-P-W-H-P-G-G-V-D-L-V-P-M-T-T-L-E-E-A-L-D-I-S-P-A-V-D-D-D-E-S-C-D-L-H-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Y-P-L-L-A-L-I-K-L-Y-Q-W-T-I-S-P-L-L-G-P-V-C-K-Y-Y-P-S-C-S-H-Y-G-Y-Q-A-I-D-R-H-G-A-I-K-G-T-A-L-T-A-W-R-I-L-R-C-N-P-W-S-L-G-G-V-D-H-V-P-P-R-K-R-P-R-W-H-E-M-L-R-N-A-W-R-A-R-K-G-G-P-S-A-A-E-P-A-I-E-G-H-I-P-S-S-P-A-A-E-T-P-S-H-V-Q-G-A"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-N-H-Q-A-R-M-R-W-R-C-R-R-G-M-L-E-L-D-I-V-L-Q-R-F-I-D-N-H-Y-E-Q-L-D-E-H-Q-L-E-L-F-E-M-L-L-S-L-S-D-H-D-L-W-N-I-I-I-G-N-T-K-E-P-N-N-Q-F-Q-P-V-L-K-L-L-Q-E-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-L-I-I-D-L-I-K-L-Y-R-Y-S-I-G-L-L-I-P-P-S-C-R-F-Y-P-T-C-S-N-Y-M-H-E-A-L-V-K-H-G-L-I-K-G-L-W-L-G-M-K-R-I-L-R-C-H-P-W-N-Q-G-G-Y-D-P-V-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-V-R-S-V-K-C-I-R-L-G-C-E-A-E-G-L-D-F-P-P-Y-P-G-E-L-G-K-R-I-F-D-N-V-S-K-E-A-W-S-Q-W-I-K-H-Q-T-M-L-V-N-E-M-R-L-N-L-A-D-I-K-A-R-K-Y-L-A-S-Q-M-E-A-Y-F-F-G-E-G-A-D-Q-P-A-G-Y-I-P-P-D-K"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-R-S-L-Y-D-G-L-N-S-L-E-T-D-L-D-S-S-V-T-Q-L-R-E-I-K-A-A-L-H-E-L-V-E-K-N-T-T-L-E-I-E-N-Q-R-L-R-E-H-L-Q-E-L-N-K-L-A-G-N-T-T-E-T-E-K-Q-E-L-S-K-S-R-M-N-L-E-K-L-Y-E-E-G-F-H-V-C-N-I-L-Y-G-S-R-R-E-N-D-E-E-C-A-F-C-L-D-V-I-Y-G-E-R-T-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-P-L-I-G-G-V-R-F-Y-Q-R-F-I-S-P-G-L-P-A-R-C-R-Y-Y-P-T-C-S-Q-Y-M-I-D-A-I-H-T-H-G-S-V-K-G-T-T-M-G-V-A-R-I-L-R-C-H-P-F-V-K-G-G-I-D-Y-V-P-L-K-F-R-L-T-K-N-P-D-E-T-Y-H-G-P-Y-T-Y-R-R-N-K-K-T-E-V-E-K-D-G"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-M-E-K-T-N-R-M-N-A-L-F-E-F-Y-S-T-L-L-T-E-K-Q-M-N-Y-M-E-L-Y-Y-A-D-D-F-S-L-G-E-I-A-E-E-Y-E-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-E-Y-E-K-K-L-H-L-Y-S-N-Y-V-V-R-K-E-F-L-E-Q-L-Q-Q-Y-V-Q-E-T-Y-P-K-D-S-E-I-K-K-Y-I-E-Q-I-Q-E-I-E-E"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-T-K-Q-I-I-K-G-I-I-I-E-R-S-S-P-L-K-I-D-E-L-S-Q-A-V-H-L-R-R-E-I-I-I-E-M-V-E-H-R-L-I-E-P-E-G-S-S-P-T-S-W-K-F-D-N-V-C-L-K-R-A-K-I-A-A-S-F-Y-R-D-L-E-I-N-M-P-G-I-A-I-A-L-D-L-L-D-K-I-E-H-L-E-Q-R-L-R-T-L-E-R-F-E-N-Q-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-R-I-V-P-R-N-I-F-I-L-F-I-I-A-Y-R-K-I-I-S-P-M-Y-G-P-V-C-K-Y-Y-P-S-C-S-E-Y-C-Q-N-S-I-A-N-N-G-V-F-L-G-A-A-Y-T-F-M-R-L-V-R-C-N-P-W-S-K-G-G-V-D-M-P-R-V-S-T-K-Y-R-V-N-K-F-G-F-A-S-R-K-N-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-R-I-V-P-R-N-I-F-I-L-F-I-I-A-Y-R-K-I-I-S-P-M-Y-G-P-V-C-K-Y-Y-P-S-C-S-E-Y-C-Q-N-S-I-A-N-N-G-V-F-L-G-A-A-Y-T-F-M-R-L-V-R-C-N-P-W-S-K-G-G-V-D-M-P-R-V-S-T-K-Y-R-V-N-K-F-G-F-A-S-R-K-N-V"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-N-L-A-S-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION This protein is involved in the attenuation mechanism for the control of the expression of the his operon structural genes ### SEQUENCE -M-T-R-V-Q-F-K-H-H-H-H-P-D"} +{"text": "### FUNCTION Could be part of an electron transfer system required for anaerobic carnitine reduction Could be a 3Fe-4S cluster-containing protein ### SEQUENCE -M-T-S-P-V-N-V-D-V-K-L-G-V-N-K-F-N-V-D-E-E-H-P-H-I-V-V-K-A-D-A-D-K-Q-V-L-E-L-L-V-K-A-C-P-A-G-L-Y-K-K-Q-D-D-G-S-V-R-F-D-Y-A-G-C-L-E-C-G-T-C-R-I-L-G-L-G-S-A-L-E-Q-W-E-Y-P-R-G-T-F-G-V-E-F-R-Y-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-Q-R-I-I-F-C-E-Y-E-K-R-D-T-E-G-L-D-F-V-P-Y-P-G-E-L-G-Q-K-I-F-A-C-I-G-K-V-G-W-A-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-N-P-S-H-R-A-F-L-E-E-E-L-N-K-F-L-F-E-R-S-A-A-K-P-E-G-Y-I-E-P-D-A"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-R-Y-C-R-C-Q-R-A-T-A-E-E-P-T-M-D-K-P-A-E-L-N-K-L-R-W-R-S-R-R-G-M-R-E-L-D-H-L-F-D-R-Y-L-S-H-C-W-A-Q-A-S-E-A-E-R-G-V-F-L-R-F-L-D-C-E-D-D-K-L-W-R-W-L-M-G-Y-E-V-C-Q-D-A-S-F-A-A-L-I-V-T-M-R-A-L-P-A"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-S-Q-L-T-Y-L-F-R-S-A-P-H-G-S-A-A-G-R-E-G-V-D-A-L-L-A-A-S-A-Y-C-E-D-I-T-V-I-F-I-G-D-G-V-Y-Q-L-L-L-G-Q-E-P-S-G-I-L-S-K-D-Y-A-P-M-L-K-L-F-D-L-Y-D-I-E-Q-V-F-V-C-S-E-S-L-A-Q-R-G-L-A-Q-A-D-L-V-I-D-A-Q-A-L-S-L-E-Q-V-K-E-K-L-Q-Q-A-G-K-L-L-S-F"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-A-R-L-K-K-E-G-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-E-A-W-A-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-D-P-E-H-R-K-L-L-E-T-E-M-V-N-F-L-F-E-G-K-D-V-H-I-E-G-Y-T-P-P-S-E"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-Y-T-P-E-E-K-A-R-I-K-W-A-C-R-R-G-M-L-E-L-D-V-V-I-M-P-F-F-E-E-C-F-D-A-L-N-E-Q-E-Q-R-D-F-V-S-L-L-E-C-D-D-P-D-L-F-T-W-V-M-G-H-G-R-S-E-N-L-G-H-A-A-M-V-D-K-I-V-A-H-N-L-S-K-V-R"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-T-Q-T-V-T-Q-A-L-Q-D-F-S-L-R-Y-Q-Q-A-W-Q-N-K-H-N-E-L-P-R-N-E-E-L-A-D-L-V-S-P-C-V-E-E-K-C-D-G-A-V-L-W-K-A-F-P-R-E-E-M-A-D-F-T-N-V-E-N-A-I-E-L-T-L-H-E-D-I-K-A-F-Y-G-S-Q-Y-S-A-D-M-D-A-T-W-Q-T-N-P-L-T-L-L-Q-V-W-S-D-D-D-F-V-R-L-Q-E-N-I-L-G-H-L-V-T-Q-R-R-L-K-L-K-P-T-V-F-I-A-A-T-D-A-E-L-D-V-I-S-I-C-N-L-T-G-N-V-I-L-E-R-L-G-T-D-K-R-E-V-L-A-E-N-V-V-E-F-L-A-K-I-E-A-A-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-K-L-A-L-V-P-I-Q-F-Y-R-Y-A-I-S-P-L-M-A-S-H-C-R-F-Y-P-S-C-S-C-Y-A-Y-E-A-I-D-N-H-G-L-L-R-G-G-W-L-S-I-R-R-L-G-R-C-H-P-W-N-P-G-G-Y-D-P-V-P-A-V-P-T-S-R-S-S-S-M-A-E"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-M-C-R-K-Y-K-E-E-L-P-G-L-E-R-A-P-Y-P-G-A-K-G-E-D-I-F-N-H-V-S-Q-K-A-W-A-D-W-Q-K-H-Q-T-L-L-I-N-E-R-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-T-E-M-D-K-F-L-S-G-E-E-Y-A-Q-A-E-G-Y-V-P-P-E-K"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-V-E-D-V-E-L-N-R-L-Y-W-H-S-R-R-G-M-L-E-L-D-V-L-L-V-P-F-V-R-E-V-Y-P-H-L-N-D-V-D-R-D-L-Y-R-R-L-L-T-C-E-D-Q-D-M-F-G-W-F-M-Q-R-A-E-S-E-D-A-E-L-Q-R-M-V-R-M-I-L-D-R-V-Q-P-K"} +{"text": "### FUNCTION May be involved in the viral transport within, and between cells ### SEQUENCE -M-A-T-T-N-C-R-I-C-G-S-S-F-A-C-P-I-N-E-R-F-S-V-C-E-S-R-G-A-T-L-S-D-F-L-L-Y-F-R-R-K-Y-I-E-T-S-P-G-L-I-S-Y-L-N-A-L-Q-A-E-I-N-E-L-F-S-A-I-K-E-V-S-R-S-E-I-R-H-G-S-C-E-D-K-C-Q-P-S-S-I-Q-K-G-K-A-E-A"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-S-S-T-L-I-V-Q-L-D-M-R-T-L-C-Q-E-A-D-V-T-A-E-C-V-I-E-I-V-E-H-G-I-V-E-P-S-G-R-T-P-E-D-W-L-F-D-D-Q-A-P-L-V-T-K-R-A-V-K-L-H-Q-E-L-E-L-E-W-E-G-V-A-L-A-L-E-L-L-Q-E-V-Q-Q-L-R-S-E-N-S-M-L-K-Q-R-L-G-R-F-I-Q-L"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-V-E-Q-T-E-L-N-R-L-F-W-H-S-R-R-G-M-L-E-L-D-V-L-L-V-P-F-T-Q-E-V-Y-P-T-L-N-E-T-D-R-E-L-Y-V-R-L-L-S-C-E-D-Q-D-M-F-G-W-F-M-E-R-T-E-S-E-D-P-E-L-Q-R-M-V-R-I-I-L-D-R-V-Q-P-K"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-T-R-T-V-M-C-R-K-Y-Q-E-E-L-P-G-L-E-R-P-P-Y-P-G-A-K-G-Q-D-I-F-E-H-I-S-Q-K-A-W-A-D-W-Q-K-H-Q-T-M-L-I-N-E-K-R-L-N-M-M-N-A-E-D-R-K-F-L-Q-A-E-M-D-K-F-F-A-G-E-E-Y-A-Q-A-E-G-Y-V-P-P-A-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-N-Y-R-I-N-S-L-F-E-F-Y-E-P-L-L-T-N-K-Q-K-A-Y-I-Q-L-Y-Y-A-D-D-Y-S-L-G-E-I-A-A-E-F-S-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-G-Y-E-A-K-L-H-L-Y-H-D-F-V-E-R-N-H-E-V-D-A-I-S-D-Y-I-K-Q-N-Y-H-G-D-T-Q-L-I-K-M-I-Q-Q-L-V-N-L-E-A-D-S-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-R-D-L-Y-D-S-F-G-E-M-E-Q-Q-M-Q-Q-M-L-D-K-M-A-K-L-R-A-D-M-T-T-V-L-E-K-N-A-E-L-V-I-E-N-E-H-L-R-E-H-M-V-E-I-E-N-E-L-P-K-K-A-A-S-T-T-T-L-S-K-S-R-Q-N-L-E-K-L-Y-D-E-G-F-H-V-C-N-Q-F-Y-G-K-R-R-D-D-D-E-S-C-V-F-C-L-E-V-I-Y-G-E-R-E-R-A"} +{"text": "### FUNCTION Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages ### SEQUENCE -M-I-T-L-Y-E-A-A-I-K-T-L-I-T-H-R-K-Q-I-L-K-H-P-D-S-R-E-I-L-L-A-L-G-L-Y-W-D-K-T-H-I-L-V-K-C-R-E-C-G-K-M-S-L-T-G-K-H-S-T-K-C-I-N-I-N-C-L-L-I-L-A-I-K-K-K-N-K-R-M-V-D-T-L-I-R-M-G-A-D-V-T-Y-I-H-L-L-K-N-K-I-K-L-S-Y-N-Q-L-S-M-L-K-S-N-S-Q-I-S-L-K-E-L-H-A-I-C-Y-L-L-Y-G-R-L-P-K-K-I-K-Q-G-M-Q-L-C-K-T-M-A-G-L-C-G-E-L-L"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-E-K-I-E-M-S-M-L-L-D-F-Y-G-I-L-L-T-D-K-Q-K-S-I-M-N-L-Y-C-N-E-D-F-S-L-A-E-I-S-E-H-T-K-T-S-R-Q-A-V-H-D-I-I-K-R-C-G-K-L-L-K-S-Y-E-E-K-L-K-L-M-G-K-H-I-E-K-I-K-A-K-K-N-M-L-N-K-L-D-Y-L-K-E-N-C-K-E-E-E-L-Q-K-L-I-E-E-L-K-N-E-L-N-N-S-L-G-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-N-K-K-N-D-I-N-R-K-I-F-C-N-F-F-K-K-Y-E-E-G-L-T-Y-I-P-Y-P-G-L-L-G-H-K-I-Y-N-E-I-S-K-L-A-W-N-K-W-I-L-Q-Q-T-I-I-I-N-E-K-K-M-N-M-L-N-K-N-D-Q-K-K-I-E-N-Y-M-I-K-F-L-F-K-N-K-Q-Q-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-H-S-A-C-E-H-C-S-T-P-V-E-G-A-L-R-L-P-R-R-F-G-R-A-L-I-W-L-Y-R-H-T-L-S-P-L-V-G-Y-N-C-R-H-L-P-T-C-S-V-Y-G-D-E-A-I-E-R-F-G-L-W-A-G-G-W-M-T-L-A-R-L-L-R-C-N-P-F-G-T-S-G-I-D-N-V-P-L-A-A-P-Q-D-A-R-W-Y-L-P-W-R-Y-G-R-W-R-G-V-N-A-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-L-K-S-L-V-R-K-V-F-S-F-L-L-L-I-P-I-Y-F-Y-R-V-C-I-S-P-L-T-P-P-S-C-R-F-T-P-T-C-S-A-Y-A-V-E-A-I-K-K-H-G-P-V-K-G-L-Y-L-A-V-R-R-I-L-R-C-H-P-W-G-G-S-G-Y-D-P-V-P"} +{"text": "### FUNCTION Involved in late/very late gene activation ### SEQUENCE -M-L-P-K-N-C-T-H-L-G-E-C-N-S-D-C-L-T-R-S-E-I-Q-A-L-F-R-E-V-I-N-T-L-K-H-T-M-N-T-E-N-V-C-A-H-M-L-D-I-V-S-F-E-R-I-K-E-Y-I-R-A-N-L-G-H-Y-T-V-I-T-D-K-C-S-K-R-K-V-C-L-H-H-K-R-I-A-R-L-L-G-I-K-K-I-Y-H-Q-E-Y-K-R-V-V-S-K-V-Y-K-K-Q-T-W"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-R-L-F-E-E-A-D-E-D-V-V-E-I-Q-R-A-H-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-A-T-G-Y-I-N-H-L-L-Q-L-I-G-P-S-I-S-Q-Q-Q-G-Y-Y-V-I-D-G-L-L-D-K-G-L-I-N-E-R-E-A-K-M-I-Q-T-I-I-D-R-E-T-L-K-M-D-V-V-A-R-D-I-I-R-A-N-I-L-K-R-L-L-P-V-I-N-Y-Y"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-K-I-L-L-S-L-V-V-F-Y-Q-R-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-Q-Y-T-R-E-A-I-E-Y-H-G-A-L-K-G-L-Y-L-G-V-R-R-I-L-K-C-H-P-L-H-K-G-G-F-D-P-V-P-L-K-K-D-K-N-S-K-T-T-H-H-H"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-G-Q-N-D-L-V-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-N-K-Q-K-N-Y-L-E-F-F-Y-L-Q-D-Y-S-L-S-E-I-A-D-T-F-E-V-S-R-Q-A-V-Y-D-N-I-R-R-T-G-D-L-V-E-D-Y-E-S-K-L-R-L-Y-Q-R-F-E-K-R-R-E-L-Y-N-L-M-K-Q-S-L-N-Q-P-E-L-L-K-Q-Y-I-T-Q-L-E-E-L-E"} +{"text": "### FUNCTION This protein is involved in the attenuation mechanism for the control of the expression of the his operon structural genes ### SEQUENCE -M-N-R-V-Q-F-N-H-H-H-H-H-H-P-D"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-S-V-L-V-Y-F-S-S-S-S-E-N-T-H-R-F-V-K-K-L-C-I-P-A-K-R-I-P-L-I-D-K-K-E-F-Q-I-K-S-P-Y-I-L-V-I-P-S-Y-N-N-G-I-L-D-T-A-V-P-H-Q-V-T-N-F-L-N-T-L-H-N-K-F-F-L-K-G-V-I-G-S-G-N-K-N-F-G-V-N-F-C-I-A-G-N-I-I-S-K-K-Y-K-V-P-L-L-Y-K-F-E-L-L-G-T-N-K-D-V-I-N-V-K-N-G-I-N-K-F-W-K-K-L-N-L-E-K-K-N-Q-N-A"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-K-I-K-N-K-S-M-V-Y-W-S-C-R-R-G-M-L-E-L-D-I-I-I-N-N-F-F-K-K-E-F-D-F-L-S-N-K-E-K-I-F-F-V-N-M-L-S-Y-D-D-I-Y-L-Y-K-C-L-I-F-N-Y-E-P-K-N-K-K-I-K-K-I-I-K-L-I-K-R-S-S-F-S-F-S"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-K-R-N-I-F-C-H-F-M-K-N-F-H-E-R-L-D-F-P-P-Y-P-G-S-I-G-K-K-I-Y-K-N-I-S-K-K-A-W-E-I-W-K-N-H-Q-T-I-L-I-N-E-K-Q-L-N-M-L-N-K-K-D-R-K-T-I-E-I-E-M-I-N-F-L-F-K-N-K"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-Y-T-T-E-E-K-A-R-I-R-W-A-C-R-R-G-M-L-E-L-D-V-V-V-M-P-F-F-E-E-C-F-E-K-L-S-E-Q-E-Q-R-D-F-V-S-L-L-E-C-D-D-P-D-L-F-T-W-V-M-G-H-G-R-S-E-N-L-G-H-A-S-M-V-D-K-I-V-A-H-N-L-S-K-V-R"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-A-R-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-D-P-E-H-R-K-L-L-E-T-E-M-V-N-F-L-F-E-G-K-E-V-H-I-E-G-Y-T-P-P-S-K"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-S-Q-L-T-Y-L-F-R-T-A-P-H-S-H-S-S-G-R-E-G-V-D-A-L-L-A-A-S-A-Y-C-E-A-I-S-V-V-F-I-G-D-G-V-Y-Q-L-L-A-G-Q-Q-T-A-S-I-L-C-K-D-Y-A-P-M-F-K-L-F-D-L-Y-D-I-E-H-V-Y-V-C-Q-Q-S-L-Q-Q-R-G-L-T-S-E-D-L-L-I-E-V-E-V-V-D-T-A-Q-L-Q-G-V-L-H-N-S-A-Q-L-L-S-F"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-S-S-P-V-S-L-A-L-A-D-F-S-Q-R-F-Q-A-A-W-Q-A-Q-H-N-A-L-P-S-S-E-E-L-A-D-L-P-S-P-C-V-V-E-S-K-G-D-E-V-L-W-R-S-V-S-L-S-A-P-V-D-F-A-N-V-E-Q-A-I-E-L-T-L-H-D-D-I-K-A-F-Y-G-S-Q-L-S-A-D-M-T-A-T-W-E-G-N-E-L-T-L-L-Q-V-W-N-D-D-D-F-T-R-L-Q-E-N-I-L-G-H-L-V-T-Q-R-R-L-K-L-K-P-T-V-F-I-A-A-T-D-A-E-L-D-V-L-S-I-C-N-I-T-G-N-V-V-L-E-R-L-G-T-S-Q-R-D-V-L-A-E-N-V-T-E-F-L-T-K-L-Q-P-M-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-N-G-L-S-K-A-L-I-V-L-I-R-I-Y-Q-R-W-I-S-P-L-F-L-P-T-C-R-Y-T-P-S-C-S-A-Y-A-V-E-A-I-A-R-Y-G-A-V-K-G-T-Y-L-A-I-R-R-I-L-R-C-H-P-F-A-V-G-G-Y-D-P-V-P-T-T-C-P-D-P-C-N-E-S-S-P-P-N-P-P-C"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-I-L-I-A-L-V-R-F-Y-Q-R-F-I-S-P-V-F-P-P-S-C-R-F-E-L-T-C-S-N-Y-M-I-Q-A-I-E-K-H-G-F-K-G-V-L-M-G-L-A-R-I-L-R-C-H-P-W-S-K-T-G-K-D-P-V-P-D-H-F-S-L-K-R-N-Q-E-G-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-A-L-F-E-F-Y-A-A-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-G-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-I-L-E-D-Y-E-M-K-L-H-M-Y-S-D-Y-I-V-R-S-Q-I-F-D-Q-I-L-E-R-Y-P-K-D-N-F-L-Q-E-Q-I-E-I-L-T-S-I-D-N-R-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-V-L-I-A-P-I-K-F-Y-Q-K-F-I-S-P-I-F-P-A-S-C-R-Y-R-P-T-C-S-A-Y-M-I-E-A-I-E-K-H-G-L-K-G-F-L-M-G-I-A-R-I-L-R-C-H-P-F-V-E-G-G-E-D-P-V-P-N-H-F-T-L-R-R-N-K-K-E-K-P-S-K-S"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-D-L-F-D-V-F-D-G-F-S-Q-N-L-M-E-T-L-A-E-A-E-A-L-K-K-Q-V-Q-D-L-V-E-Q-N-A-S-L-R-L-E-N-D-K-L-R-D-R-L-S-H-F-S-Q-M-E-E-S-D-P-S-S-K-A-I-S-S-R-K-E-N-L-E-N-I-Y-E-D-G-F-H-I-C-T-F-F-Y-G-Q-R-R-E-N-N-E-D-C-A-F-C-M-E-L-L-Y-R-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-D-L-F-D-A-F-D-D-F-S-Q-N-L-L-V-G-L-S-E-I-E-T-M-K-K-Q-I-Q-K-L-L-E-E-N-T-V-L-R-I-E-N-G-K-L-R-E-R-L-S-V-I-E-A-E-T-E-T-A-V-K-N-S-K-Q-G-R-E-L-L-E-G-I-Y-N-D-G-F-H-I-C-N-T-F-Y-G-Q-R-R-E-N-D-E-E-C-A-F-C-I-E-L-L-Y-R-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-D-L-F-D-A-F-D-D-F-S-Q-N-L-L-V-G-L-S-E-I-E-T-M-K-K-Q-I-Q-K-L-L-E-E-N-T-V-L-R-I-E-N-G-K-L-R-E-R-L-S-V-I-E-A-E-T-E-T-A-V-K-N-S-K-Q-G-R-E-L-L-E-G-I-Y-N-D-G-F-H-I-C-N-T-F-Y-G-Q-R-R-E-N-D-E-E-C-A-F-C-I-E-L-L-Y-R-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Q-T-Q-S-P-L-Q-W-L-A-T-T-L-I-R-G-Y-Q-I-F-I-S-P-I-L-G-P-R-C-R-F-N-P-T-C-S-H-Y-A-I-E-A-I-K-V-H-G-T-A-K-G-C-W-F-A-L-K-R-I-L-K-C-H-P-L-H-P-G-G-S-D-P-V-P-P-K-N-D-R-C-N-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-F-I-F-I-G-L-I-K-F-Y-R-S-A-I-S-P-F-T-P-S-S-C-R-F-Y-P-T-C-S-E-Y-G-L-E-A-I-K-R-F-G-A-F-K-G-G-I-L-T-I-K-R-I-S-K-C-H-P-F-H-P-G-G-V-D-V-V-P-D-K-V-K-N-I-N-N-E-K-H-L-E-K-G-V-I-R-N-E-D"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-D-K-T-T-R-I-N-Y-L-F-D-F-Y-Q-E-L-L-T-P-K-Q-R-N-Y-M-E-M-Y-Y-L-E-D-Y-S-L-G-E-I-S-E-L-F-Q-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-S-Y-E-E-K-L-H-L-Y-S-K-F-E-Q-R-V-K-L-L-E-K-L-K-L-M-T-T-D-K-H-V-H-E-H-I-Q-K-L-K-D-L-D"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-V-T-D-V-R-L-R-R-V-N-T-E-G-R-M-R-A-I-A-S-I-T-L-D-Q-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-G-T-R-S-K-I-Q-E-A-V-L-A-E-Y-Q-K-A-G-E-D-E-V-N-Y-E-E-A-G-A-S"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-K-E-L-D-L-S-Q-I-S-L-L-I-D-F-Y-G-N-L-L-T-D-K-Q-L-Q-N-L-I-D-Y-Y-F-N-D-L-S-L-S-E-I-A-A-N-N-N-V-S-R-T-A-I-H-D-S-I-K-K-S-K-N-E-L-E-Q-F-E-N-K-L-K-F-I-Y-R-F-N-L-R-K-E-I-Y-K-Q-I-K-D-N-N-L-L-D-Q-L-L-E-T-E-V-E-Q-L-W-K-T-K"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-S-Y-S-N-I-L-V-A-V-A-V-T-P-E-S-Q-Q-L-L-A-K-A-V-S-I-A-R-P-V-K-G-H-I-S-L-I-T-L-A-S-D-P-E-M-Y-N-Q-L-A-A-P-M-L-E-D-L-R-N-V-M-Q-E-E-T-Q-S-F-L-D-K-L-I-Q-D-A-G-Y-P-V-D-K-T-F-I-A-Y-G-E-L-S-E-H-I-L-E-V-C-R-K-H-H-F-D-L-V-I-C-G-N-H-N-H-S-F-F-S-R-A-S-C-S-A-K-R-V-I-T-S-S-E-V-D-V-L-L-V-P-L-T-G-D"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-V-T-V-T-F-T-I-T-E-F-C-L-H-T-G-I-S-E-E-E-L-N-E-I-V-G-L-G-V-V-E-P-S-E-I-Q-E-T-T-W-V-F-D-D-H-A-A-I-V-V-Q-R-A-V-R-L-R-H-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-M-D-D-I-A-H-L-K-Q-E-N-R-L-L-R-Q-R-L-S-R-F-V-A-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-C-E-P-I-S-D-D-P-Q-V-I-P-Q-P-K-G-P-A-A-K-A-L-A-G-A-V-R-F-Y-Q-K-Y-L-S-G-L-K-M-G-S-T-C-R-F-D-P-V-C-S-T-Y-A-L-K-S-V-S-V-H-G-A-V-K-G-T-V-L-A-A-V-R-L-A-K-C-G-P-W-H-P-G-G-F-D-P-V-P-N-P-G-Y-W-S-T-E-T-V-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-S-C-G-G-K-H-T-G-K-G-A-P-K-P-Y-S-R-N-F-T-D-P-W-R-K-T-P-G-R-L-F-G-T-A-L-I-R-F-Y-Q-I-T-L-S-S-L-I-G-N-S-C-R-H-L-P-T-C-S-E-Y-A-Y-E-A-I-A-R-H-G-L-W-R-G-G-W-M-G-F-F-R-V-V-R-C-G-P-F-G-T-H-G-F-D-P-V-P-R-E-L-S-P-D-L-K-W-Y-M-P-W-R-Y-W-R-C-S-A-S-R-T-G-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-A-S-F-K-A-V-M-I-G-G-V-R-W-Y-Q-Q-H-I-S-A-N-T-P-P-C-C-K-Y-Y-P-T-C-S-N-Y-A-I-E-A-L-E-R-Y-G-A-F-K-G-G-V-L-A-V-L-R-L-L-R-C-R-P-W-S-R-G-G-I-D-D-V-P-Q-R-Y-S-V-F-Y-R-F-S-W-S-K-A-H-E-E-P-R-L-T-P-L-A-T-T-Q-R-E-A-Q-R"} +{"text": "### FUNCTION Involved in the biosynthesis of albonoursin activity ### SEQUENCE -M-N-P-G-E-T-V-L-P-P-Q-L-R-E-E-I-A-L-L-A-V-Y-L-L-S-S-G-R-G-L-L-E-E-P-A-D-Y-G-I-Y-R-C-T-D-G-A-R-R-A-L-Q-L-L-D-E-H-G-G-S-T-A-R-L-T-A-V-R-E-R-L-D-E-V-M-F-A-P-M-G-E-D-R-D-M-G-A-I-L-D-D-L-C-R-Q-M-A-D-A-L-P-E-I-E-T-P"} +{"text": "### FUNCTION Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors ### SEQUENCE -M-A-D-S-E-T-P-Y-H-P-D-P-E-D-L-R-R-I-P-V-D-L-F-A-S-K-K-L-P-G-L-S-S-G-D-L-G-F-A-D-S-S-E-H-L-V-F-I-L-R-K-S-S-S-S-L-K-S-L-L-D-S-S-G-V-P-L-F-S-I-S-R-L-H-N-G-V-W-E-L-H-K-G-D-V-E-K-R-K-D-L-V-L-T-V-K-R-T-S-K-R-F-S-K-T-E-S-E-V-S-F-A-G-E-S-S-E-N-L-V-I-K-G-V-P-F-Q-K-S-C-T-I-Y-S-Q-D-S-I-V-A-Q-T-S-L-M-Y-K-L-R-Q-I-Y-V-G-R-S-K-F-R-L-T-I-F-P-G-S-I-D-H-S-L-V-V-A-M-V-A-I-F-L-Q-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-N-R-I-I-F-C-T-F-L-Q-K-K-S-E-G-Q-D-Y-P-P-Y-P-G-K-L-G-E-K-I-Y-N-Q-I-S-K-I-A-W-K-E-W-K-L-Q-Q-T-K-L-I-N-E-E-K-L-N-M-F-N-Q-N-D-R-K-K-I-E-K-Y-M-K-L-F-L-F-N-N-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-N-I-V-P-I-L-L-I-R-F-Y-Q-S-F-I-S-P-L-L-G-P-S-C-K-Y-H-P-T-C-S-N-Y-A-I-E-A-F-R-Q-H-N-F-F-Y-A-S-W-L-T-V-W-R-V-L-R-C-N-P-F-S-K-G-G-Y-D-P-V-P-P-K-S-V-K-S-A-G-N-S-K-D-S-K"} +{"text": "### FUNCTION Putative control of replication message ### SEQUENCE -M-T-F-N-K-I-F-K-Y-L-I-S-L-L-F-L-S-I-L-F-H-T-I-I-H-K-N-N-L-V-F-S-K-T-M-H-K-K-V-A-F-F-S-F-S-I-F-F-V-W-I-R-H-L-K-R-Y-N-S-M-L-E-K-A-T-F-F-V-L-Q-T-S-Y-T-N-E-L-K-G-L-Y-I-A-G-N-S-Y-P-Y-Y-Q-D-K-K-K-L-V-F-N-S-F-Q-K-P-F-K-N-H-Q-S-T-K-I-P-R-E"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-V-P-D-K-N-A-T-S-E-D-S-E-E-A"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-R-N-E-I-F-E-K-I-M-R-L-E-M-N-V-N-Q-L-S-K-E-T-S-E-L-K-A-L-A-V-E-L-V-E-E-N-V-A-L-Q-L-E-N-D-N-L-K-K-V-L-G-N-D-E-P-T-T-I-D-T-A-N-S-K-P-A-K-A-V-K-K-P-L-P-S-K-D-N-L-A-I-L-Y-G-E-G-F-H-I-C-K-G-E-L-F-G-K-H-R-H-G-E-D-C-L-F-C-L-E-V-L-S-D"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-S-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-H-L-E-H-E-T-V-A-K-N-P-F-K-Q-R-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-M-K-K-L-L-I-V-S-V-K-A-Y-Q-K-Y-I-S-P-L-S-P-P-S-C-R-Y-K-P-T-C-S-A-Y-M-L-T-A-I-E-K-H-G-T-K-G-I-L-M-G-I-A-R-I-L-R-C-H-P-F-V-A-G-G-V-D-P-V-P-E-D-F-S-L-M-R-N-K-N-T-S-K-N-E-K-F"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Y-H-W-Q-V-I-G-R-L-L-I-A-L-L-R-F-Y-K-R-F-I-S-P-L-L-G-P-R-C-R-F-A-P-S-C-S-E-Y-A-M-T-A-I-A-R-F-G-P-L-R-G-S-W-L-A-A-R-R-L-G-R-C-H-P-F-H-P-G-G-F-D-P-V-P-D-A-P-T-S-S-P-S-S-C-R-C-K-G-P-H-P"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-H-Y-Q-Q-S-D-A-E-G-L-D-F-V-P-Y-P-G-E-L-G-Q-R-I-F-A-Q-I-G-K-N-A-W-Q-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-D-P-K-H-R-A-F-L-E-A-E-L-Q-K-F-L-F-E-R-N-A-D-K-P-E-G-Y-V-A-P-V-G-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-Y-H-W-Q-V-I-S-R-L-L-I-A-L-L-R-V-Y-K-L-V-I-S-P-L-L-G-P-R-C-R-F-A-P-S-C-S-D-Y-A-M-T-A-I-G-R-F-G-P-L-R-G-S-W-L-A-A-R-R-L-G-R-C-H-P-F-H-P-G-G-F-D-P-V-P-D-A-P-T-S-P-S-P-S-S-S-C-S-C-K-G-P-H-P"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-W-F-A-A-A-P-A-L-G-S-G-A-A-V-V-F-G-P-P-C-G-A-V-E-S-E-M-D-E-Q-T-L-L-K-K-L-R-W-R-C-R-R-G-M-R-E-L-D-Q-L-F-G-R-Y-L-D-Q-R-W-A-Q-A-P-D-A-E-R-A-V-F-L-Q-L-L-D-C-E-D-D-K-L-W-R-W-F-M-G-Y-E-A-C-P-D-A-A-N-A-A-L-I-A-D-I-R-A-L-P-A"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-L-V-T-T-S-R-K-P-S-A-K-S-R-T-L-C-K-L-L-S-R-F-T-A-S-R-C-I-S-R-G-K-M-G-M-Q-E-L-L-D-F-T-E-G-N-T-F-I-V-V-G-E-Y-H-G-N-P-G-E-L-S-F-H-D-N-E-G-K-L-L-F-S-I-R-F-S-D-R-Y-S-E-E-I-D-S-Y-W-F-P-D-V-L-P-V-L-T-G-E-G-E-I-A-E-A-L-E-S-F-F-H-F-E-R-V-E-S-D-R-V-V-Q-L-P-Q-N-S-L-V-M-A-I-G-D-K-E-I-D-F-M-G-S-G-K-S-L-F-K-F-N-I-K-G-F-K-K-Y"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-P-T-R-T-I-S-I-S-E-E-A-Y-E-R-L-K-S-L-K-T-S-E-K-D-S-F-S-D-V-I-L-K-Y-Y-P-R-K-R-K-L-S-E-V-L-A-E-I-G-S-N-P-E-L-A-D-A-I-E-K-A-S-R-D-M-R-K-A-K-M-R-N-V-D-L-D-A-G-A"} +{"text": "### FUNCTION Self-assembles to form a helical, filamentous nucleocapsid The capsid proteins wrap around the DNA and maintain it in an A-form by non-specific desolvation and specific coordination of the DNA phosphate groups by positively charged residues This certainly protects the viral DNA under conditions such as the extreme desiccation of its host ### SEQUENCE -M-A-K-G-H-T-K-R-S-Y-S-Q-R-Y-A-K-W-Q-A-K-F-N-A-F-S-N-P-T-V-A-S-T-I-L-S-N-V-A-P-V-A-Q-Q-N-F-Q-T-N-V-P-T-F-T-A-V-N-E-N-V-S-A-V-L-S-Q-Y-G-I-T-G-P-N-R-A-I-Y-Q-G-F-G-L-K-I-A-R-A-L-N-R-I-G-S-G-P-A-L-V-N-M-I-N-G-L-K-S-Y-Y-I-S-A-F-N-A-N-P-Q-V-L-D-A-V-V-N-I-I-T-G-S-P-T-G-Y-V-S"} +{"text": "### FUNCTION Involved in late/very late gene activation ### SEQUENCE -M-D-E-P-R-P-E-A-A-N-V-D-S-Q-Q-N-S-Q-C-C-L-T-R-S-E-V-Y-A-L-V-R-E-V-I-N-K-R-K-H-H-N-L-V-T-N-V-C-D-H-V-F-D-D-G-F-E-E-Q-L-K-Y-I-R-A-N-I-D-K-A-L-I-T-V-G-G-E-H-K-H-C-K-R-L-A-A-H-I-K-K-I-N-K-I-F-K-L-N-K-S-L-E-T-E-Y-K-Q-S-I-D-R-Y-G-S-N-R-F-N-R-N-N"} +{"text": "### FUNCTION May have a potential role in hypercalcemia of malignancy ### SEQUENCE -M-A-Q-G-Q-R-K-F-Q-A-Q-K-P-K-S-K-A-A-A-A-E-R-S-R-G-P-R-K-G-G-R-V-I-A-P-K-K-A-R-V-V-Q-Q-Q-K-L-K-K-S-L-E-V-G-I-R-K-K-I-E-H-D-V-V-M-K-A-S-S-S-L-P-K-R-L-A-L-L-K-G-A-S-K-K-S-E-A-T-I-P-G-K-T-P-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-N-F-V-I-F-L-I-R-L-Y-Q-K-Y-I-S-P-M-K-P-R-T-C-R-F-Y-P-T-C-S-Q-Y-S-I-E-A-I-S-K-Y-G-L-L-K-G-G-L-M-S-I-W-R-I-L-R-C-N-P-F-N-P-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-I-T-D-V-R-V-R-K-L-N-D-E-G-R-M-K-A-V-V-S-V-T-F-D-N-E-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-E-G-E-F-K-D-I-A-H-P-I-N-S-D-T-R-N-K-L-Q-K-A-I-L-E-E-Y-E-K-A-K-E-N-N-S-N-K-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle ### SEQUENCE -M-E-D-D-F-L-F-M-T-L-L-Y-D-F-Y-G-A-L-L-T-D-K-Q-R-E-I-F-E-M-Y-Y-L-N-D-Y-S-L-G-E-I-S-E-I-L-D-I-S-R-Q-G-V-Y-D-A-L-K-R-A-E-D-S-L-E-F-Y-E-E-K-L-G-L-V-K-K-H-Q-E-M-M-K-K-I-E-K-I-K-E-C-I-K-L-I-K-E-R-E-K-D-E-E-I-L-K-I-I-E-D-M-A-R-E-L-E-E-L-N-P"} +{"text": "### FUNCTION Might take part in the signal recognition particle ### SEQUENCE -M-I-L-D-E-F-V-E-I-A-N-L-L-E-I-Y-S-S-L-L-S-E-K-Q-K-E-Y-L-E-D-H-F-E-N-D-L-S-L-S-E-I-A-K-N-N-N-V-S-R-Q-A-I-Y-D-N-I-K-R-G-V-A-L-L-Y-D-Y-E-D-K-L-K-F-Y-Q-M-K-K-N-I-R-K-E-L-V-D-L-K-E-D-F-T-K-E-N-L-E-K-I-I-E-N-L-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-I-L-I-L-L-I-R-F-Y-Q-K-F-I-S-P-M-F-P-A-K-C-R-F-Y-P-T-C-S-Q-Y-T-L-E-A-I-K-E-H-G-T-I-K-G-T-Y-L-A-I-R-R-I-L-K-C-H-P-F-H-E-G-G-Y-D-P-V-P-K-R-K-N-K-N-S-E-G-K-R-E-E"} +{"text": "### FUNCTION The metallothioneins are involved in the cellular sequestration of toxic metal ions Binds 12 cadmium ions per molecule ### SEQUENCE -M-D-K-V-N-N-N-C-C-C-G-E-N-A-K-P-C-C-T-D-P-N-S-G-C-C-C-V-S-E-T-N-N-C-C-K-S-D-K-K-E-C-C-T-G-T-G-E-G-C-K-W-T-G-C-K-C-C-Q-P-A-K-S-G-C-C-C-G-D-K-A-K-A-C-C-T-D-P-N-S-G-C-C-C-S-S-K-T-N-K-C-C-D-S-T-N-K-T-E-C-K-T-C-E-C-C-K"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-L-I-T-T-S-R-K-P-S-A-K-T-R-T-L-C-K-L-L-S-R-F-I-T-G-R-C-I-T-R-G-K-M-G-M-Q-E-L-I-G-F-A-E-G-G-P-L-I-V-V-G-E-Y-H-G-N-P-G-E-L-G-F-Y-D-D-A-G-K-L-L-F-S-L-R-F-S-D-W-Y-S-E-D-I-G-S-Y-W-F-P-D-L-E-P-V-L-A-G-Q-G-E-I-A-D-A-F-E-S-F-F-H-F-K-R-V-E-S-E-E-V-D-Q-L-P-P-L-S-T-V-L-V-A-G-E-K-E-I-D-F-T-G-S-G-K-S-L-F-K-L-N-V-K-G-F-K-K-Y"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-P-T-R-T-I-S-I-S-E-E-A-Y-E-K-L-K-S-L-K-S-S-E-K-D-S-F-S-D-V-I-L-R-Y-Y-P-K-K-R-K-L-S-E-V-L-A-E-I-G-P-N-P-E-L-A-D-A-I-E-K-V-S-G-E-M-R-A-E-K-M-R-E-I-D-P-E-S"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-R-P-A-A-I-T-T-S-Q-R-P-A-R-R-T-R-S-L-C-R-D-L-E-C-A-L-P-D-A-T-Y-V-L-R-G-T-K-N-L-R-D-T-V-L-E-A-L-E-S-G-A-E-V-L-F-Y-V-T-E-A-K-G-N-P-A-R-L-H-V-I-D-L-G-E-I-P-P-R-L-R-L-S-F-W-L-G-G-V-K-L-Q-R-E-L-F-G-N-R-V-D-L-S-G-D-L-V-I-T-T-S-K-R-P-V-S-G-H-M-K-V-A-E-S-L-S-E-V-L-G-V-E-F-V-P-R-A-G-S-L-E-D-V-L-E-E-A-L-A-D-V-L-L-V-V-E-G-H-P-R-H-L-G-T-L-T-F-Y-R-R-T-E-K-V-G-P-S-L-F-Y-R-D-F-R-T-K-D-E-R-M-K-L"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-Q-V-I-E-A-I-Y-E-D-G-V-L-K-P-L-K-K-L-K-L-K-E-H-S-K-V-I-I-K-I-I-D-E-E-E-L-E-K-I-L-D-S-M-V-I-E-K-V-E-G-I-D-Y-K-K-L-K-E-A-Y-Y-E-S-L"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-I-L-K-P-S-K-P-Y-S-F-C-F-T-T-Y-P-W-K-K-L-K-L-K-E-H-S-K-V-I-I-K-I-I-D-E-E-E-I-E-K-I-L-D-S-M-I-I-E-K-V-E-G-I-D-Y-K-K-L-K-E-T-H-Y-E-S-L"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-V-K-T-I-T-I-S-D-D-V-Y-N-E-L-L-R-I-K-G-N-K-S-F-S-E-V-L-R-E-L-L-K-E-R-K-G-N-K-E-V-L-K-R-I-F-G-I-L-S-E-E-E-Y-Q-E-V-K-K-R-L-K-E-L-E-G-E-F-E-K-W-E-Q-S-L-T-Q-M"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-V-K-T-I-T-V-S-D-D-V-Y-N-E-L-L-R-I-K-G-K-K-S-F-S-E-L-L-R-E-L-L-R-E-K-K-G-N-S-V-A-L-K-H-I-Y-G-I-L-N-G-E-E-Y-R-E-T-R-K-R-L-K-E-L-E-K-E-F-E-K-W-K-Q-F-L-T-Q-V"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-Q-I-V-E-A-I-Y-E-D-G-V-L-K-L-L-K-N-L-K-L-K-E-H-S-K-V-I-I-K-V-I-D-E-E-E-I-E-K-I-L-D-S-R-D-Y"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-C-G-E-P-G-C-R-H-E-Q-T-A-V-K-A-G-R-S-R-N-W-A-G-S-F-A-K-T-P-G-R-L-F-G-V-G-F-I-R-L-Y-Q-L-T-L-S-G-F-V-G-N-S-C-R-H-I-P-T-C-S-E-Y-G-Y-E-A-I-A-R-H-G-L-W-A-G-G-W-M-A-L-F-R-V-A-R-C-G-P-G-G-T-S-G-L-D-P-V-P-E-E-L-D-G-S-K-R-W-W-T-P-W-R-Y-W-S-R-H-R"} +{"text": "### FUNCTION More likely to influence phosphoinositide metabolism than actin assembly ### SEQUENCE -M-V-E-W-H-K-I-I-E-D-I-S-K-N-N-K-F-E-D-A-A-I-V-D-Y-K-T-T-K-N-V-L-A-A-I-P-N-R-T-F-A-K-I-N-P-G-E-V-I-P-L-I-T-N-H-N-I-L-K-P-L-I-G-Q-K-F-C-I-V-Y-T-N-S-L-M-D-E-N-T-Y-A-M-E-L-L-T-G-Y-A-P-V-S-P-I-V-I-A-R-T-H-T-A-L-I-F-L-M-G-K-P-T-T-S-R-R-D-V-Y-R-T-C-R-D-H-A-T-R-V-R-A-T-G-N"} +{"text": "### FUNCTION More likely to influence phosphoinositide metabolism than actin assembly ### SEQUENCE -M-A-E-W-H-K-I-I-E-D-I-S-K-N-N-K-F-E-D-A-A-I-V-D-Y-K-T-T-K-N-V-L-A-A-I-P-N-R-T-F-A-K-I-N-P-G-E-V-I-P-L-I-T-N-H-N-I-L-K-P-L-I-G-Q-K-F-C-I-V-Y-T-N-S-L-M-D-E-N-T-Y-A-M-E-L-L-T-G-Y-A-P-V-S-P-I-V-I-A-R-T-H-T-A-L-I-F-L-M-G-K-P-T-T-S-R-R-D-V-Y-R-T-C-R-D-H-A-T-R-V-R-A-T-G-N"} +{"text": "### FUNCTION Plays a role for multiplication of the virus in different cell types ### SEQUENCE -M-G-I-Q-H-E-F-D-I-I-I-N-G-D-I-A-L-R-N-L-Q-L-H-R-G-D-N-Y-G-C-K-L-K-I-I-S-N-D-Y-K-K-L-K-L-R-F-V-I-R-P-D-W-S-E-I-D-E-V-K-G-L-T-V-F-A-N-N-Y-A-V-K-V-N-K-V-D-Y-T-L-Y-Y-V-I-Y-E-A-V-I-H-L-Y-N-K-K-T-E-I-L-I-Y-S-D-D-E-N-E-L-F-K-H-Y-Y-P-Y-I-S-L-N-M-I-S-K-K-Y-K-I-K-E-E-N-Y-S-S-P-Y-I-E-H-P-L-I-P-Y-R-D-Y-E-S-M-D"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-T-I-T-A-Q-A-P-A-F-G-N-W-L-T-P-G-D-F-L-N-F-A-K-K-I-W-A-P-V-A-E-S-N-I-E-A-M-E-R-K-V-D-E-L-Y-G-A-A-C-K-R-Y-P-T-Y-D-T-M-V-Q-N-A-F-C-A-S-M-D-A-A-F-G-T-D-E-Q-A-E-G-V-A-E-V-F-A-Y-A-R-D-A-Y-G-Y-M-S-A-S-E-R-E-A-Q-R-Q-E-D-A-D-N-G-I-C-S-H-G-L-D-S-M-T-C-P-C-G-C-F-E-N-D"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-S-Y-S-N-I-L-V-A-V-A-V-T-P-E-S-Q-Q-L-L-A-K-A-V-S-I-A-R-P-V-K-G-H-I-S-L-I-T-L-A-S-D-P-E-M-Y-N-Q-L-A-A-P-M-L-E-D-L-R-S-V-M-Q-E-E-T-Q-S-F-L-D-K-L-I-Q-D-A-G-Y-P-V-D-K-T-F-I-A-Y-G-E-L-S-E-H-I-L-E-V-C-R-K-Y-H-F-D-L-V-I-C-G-N-H-N-H-S-F-F-S-R-A-S-C-S-A-K-R-V-I-A-S-S-E-V-D-V-L-L-V-P-L-T-G-D"} +{"text": "### FUNCTION Interacts with the SecY protein in vivo May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function ### SEQUENCE -M-D-D-L-T-A-Q-A-L-K-D-F-T-A-R-Y-C-D-A-W-H-E-E-H-K-S-W-P-L-S-E-E-L-Y-G-V-P-S-P-C-I-I-S-T-T-E-D-A-V-Y-W-Q-P-Q-P-F-T-G-E-Q-N-V-N-A-V-E-R-A-F-D-I-V-I-Q-P-T-I-H-T-F-Y-T-T-Q-F-A-G-D-M-H-A-Q-F-G-D-I-K-L-T-L-L-Q-T-W-S-E-D-D-F-R-R-V-Q-E-N-L-I-G-H-L-V-T-Q-K-R-L-K-L-P-P-T-L-F-I-A-T-L-E-E-E-L-E-V-I-S-V-C-N-L-S-G-E-V-C-K-E-T-L-G-T-R-K-R-T-H-L-A-P-N-L-A-E-F-L-N-Q-L-K-P-L-L"} +{"text": "### FUNCTION This protein is involved in the attenuation mechanism for the control of the expression of the his operon structural genes ### SEQUENCE -M-T-R-V-Q-F-K-Q-H-H-H-H-H-H-P-D"} +{"text": "### FUNCTION Represses expression of mcbR ### SEQUENCE -M-T-N-L-T-L-D-V-N-I-I-D-F-P-S-I-P-V-A-M-L-P-H-R-C-R-P-E-L-L-N-Y-S-V-A-K-F-I-M-W-R-K-E-T-G-L-S-P-V-N-Q-S-Q-T-F-G-V-A-W-D-D-P-A-T-T-A-P-E-A-F-R-F-D-I-C-G-S-V-S-E-P-I-P-D-N-R-Y-G-V-S-N-G-E-L-T-G-G-R-Y-A-V-A-R-H-V-G-E-L-D-D-I-S-H-T-I-W-G-I-I-R-H-W-L-P-A-S-G-E-K-M-R-K-A-P-I-L-F-H-Y-T-N-L-A-E-G-V-T-E-Q-R-L-E-T-N-V-Y-V-P-L-A"} +{"text": "### FUNCTION Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA Together with CbpA, modulates the activity of the DnaK chaperone system Does not inhibit the co-chaperone activity of DnaJ ### SEQUENCE -M-A-N-I-T-V-T-F-T-I-T-E-F-C-L-H-T-G-V-T-E-E-E-L-N-E-I-V-G-L-G-V-I-E-P-Y-E-D-D-N-A-D-W-Q-F-D-D-R-A-A-S-V-V-Q-R-A-L-R-L-R-E-E-L-A-L-D-W-P-G-I-A-V-A-L-T-L-L-E-E-N-S-R-L-R-E-E-N-R-L-L-L-Q-R-L-S-R-F-I-S-H-P"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-F-I-V-M-I-K-F-Y-R-K-Y-I-S-P-L-K-R-P-C-C-R-F-Y-P-T-C-S-Q-Y-A-L-E-A-I-Q-K-Y-G-A-F-K-G-G-F-M-S-I-G-R-I-L-R-C-N-P-F-C-K-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-N-I-T-D-V-R-I-R-K-I-S-A-E-G-K-M-K-A-I-V-S-V-T-F-E-N-Q-F-V-V-H-D-I-K-V-I-E-G-Q-N-G-L-F-I-A-M-P-S-R-K-T-P-D-G-E-F-K-D-I-A-H-P-I-N-T-E-T-R-E-Q-I-Q-K-A-I-L-D-E-Y-E-K-V-K-N-L-D-V-Q-E"} +{"text": "### FUNCTION Might take part in the signal recognition particle ### SEQUENCE -M-E-N-R-F-E-I-S-M-L-I-D-Y-Y-G-T-L-L-T-E-K-Q-F-N-V-M-T-L-Y-Y-N-E-D-L-S-L-A-E-I-A-E-I-N-K-T-S-R-Q-A-I-Y-D-L-I-K-R-C-S-K-Q-L-H-S-Y-D-E-K-L-K-L-S-K-K-V-D-K-R-Y-R-I-K-E-E-L-M-A-E-L-N-K-N-S-N-L-D-E-N-I-K-K-Y-I-D-E-K-L-E-E-I-I-N-A"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-T-A-V-N-T-S-T-F-S-H-Q-S-D-P-H-R-R-A-R-L-R-W-R-A-R-R-G-L-L-E-N-D-I-I-V-E-R-F-F-N-R-Y-E-T-E-L-S-D-D-D-V-G-A-L-T-Q-L-F-E-L-P-D-N-D-L-M-D-L-L-L-A-R-K-E-P-E-G-A-L-D-V-P-S-V-R-H-V-L-S-L-L-R-A-V"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-M-V-H-C-V-K-L-N-K-E-A-E-G-L-D-F-P-P-L-P-G-E-L-G-K-K-I-W-Q-S-V-S-K-E-A-W-A-G-W-L-K-H-Q-T-M-L-I-N-E-N-R-L-N-M-A-D-T-R-A-R-Q-Y-L-L-K-Q-T-E-K-Y-F-F-G-E-G-A-D-Q-A-S-G-Y-V-P-P-P-S-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-R-V-L-L-F-L-L-R-V-Y-K-V-A-F-S-P-F-V-G-A-Q-C-R-F-L-P-T-C-S-D-Y-A-R-D-A-V-L-T-H-G-P-A-I-G-S-Y-L-A-A-K-R-L-C-R-C-H-P-F-A-Q-G-G-Y-D-P-V-P-P-A-A-G-D-A-A-L-R-S-T-D-S-A-S-T-E-T-T-A-A-D-A-P-A-A-R-P-S-I-H-L-P-R-P"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-F-E-K-T-N-R-M-N-L-L-F-D-F-Y-Q-E-L-L-T-T-K-Q-K-A-Y-V-S-F-Y-Y-L-D-D-Y-S-L-G-E-I-A-E-E-F-E-V-S-R-Q-A-I-Y-D-N-I-K-R-T-E-E-S-L-E-K-Y-E-E-K-L-G-M-L-K-K-Y-Q-Q-R-E-K-L-F-T-Q-L-E-A-Q-L-T-K-K-N-F-L-D-E-Q-V-K-D-T-L-E-Q-L-K-N-I-D"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-G-S-C-G-G-K-H-T-G-K-G-A-P-K-P-Y-S-R-N-F-T-D-P-W-R-K-T-P-G-R-L-F-G-T-A-L-I-R-F-Y-Q-I-T-L-S-S-L-I-G-N-S-C-R-H-L-P-T-C-S-E-Y-A-Y-E-A-I-A-R-H-G-L-W-R-G-G-W-M-G-F-F-R-V-V-R-C-G-P-F-G-T-H-G-F-D-P-V-P-R-E-L-S-P-D-L-K-W-Y-M-P-W-R-Y-W-R-C-S-A-S-R-I-G-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-Q-I-F-I-W-L-I-K-G-Y-R-M-F-I-S-P-L-Y-P-P-T-C-R-F-R-P-T-C-S-M-Y-A-I-E-A-I-E-R-F-G-V-F-R-G-G-W-M-A-I-R-R-I-L-R-C-H-P-F-H-P-G-G-Y-D-P-V-P-E-L-G-E-H-C-C-H-H-D-S-G-N-K-G"} +{"text": "### FUNCTION This protein is involved in the attenuation mechanism for the control of the expression of the his operon structural genes ### SEQUENCE -M-T-R-V-Q-F-K-H-H-H-H-P-D"} +{"text": "### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-S-Y-T-H-I-L-V-A-V-A-V-T-P-E-S-H-Q-L-L-A-K-A-V-S-I-A-R-P-V-Q-A-K-V-S-L-I-T-L-A-S-D-P-E-L-Y-N-Q-F-A-A-P-M-M-E-D-L-R-A-V-M-H-E-E-T-E-N-F-L-K-M-L-G-E-K-A-D-Y-P-I-E-Q-T-F-I-A-S-G-E-L-S-Q-H-I-L-A-V-C-R-K-H-H-V-D-L-V-I-C-G-N-H-N-H-S-F-F-S-R-A-S-C-S-A-K-V-S-S-A-P-A-R"} +{"text": "### FUNCTION Putative virulence protein ### SEQUENCE -M-L-A-V-L-K-G-I-P-L-I-Q-D-I-R-A-E-G-N-S-R-S-W-I-M-T-I-D-G-H-P-A-R-G-E-I-F-S-E-A-F-S-I-S-L-F-L-N-D-L-E-S-L-P-K-P-C-L-A-Y-V-T-L-L-L-A-A-H-P-D-V-H-D-Y-A-I-Q-L-T-A-D-G-G-W-L-N-G-Y-Y-T-T-S-S-S-S-E-L-I-A-I-E-I-E-K-H-L-A-L-T-C-I-L-K-N-V-I-R-N-H-H-K-L-Y-S-G-G-V"} +{"text": "### FUNCTION Involved in control of the biosynthesis of leucine ### SEQUENCE -M-S-Y-I-V-R-F-T-G-L-L-L-L-N-A-F-I-V-R-G-R-P-V-G-G-I-Q-H"} +{"text": "### FUNCTION Could be part of an electron transfer system required for anaerobic carnitine reduction Could be a 3Fe-4S cluster-containing protein ### SEQUENCE -M-T-S-P-V-N-V-D-V-K-L-G-V-N-K-F-N-V-D-E-D-S-P-H-I-I-L-K-T-D-P-D-K-Q-A-L-E-V-L-V-K-A-C-P-A-G-L-Y-K-K-Q-D-D-G-S-V-R-F-D-Y-A-G-C-L-E-C-G-T-C-R-I-L-G-L-D-T-A-L-E-K-W-E-Y-P-R-G-T-F-G-V-E-F-R-Y-G"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-E-G-G-C-K-V-I-I-T-T-S-R-E-P-S-K-K-T-L-E-L-V-N-D-L-V-N-S-L-P-G-T-S-K-I-V-R-G-K-K-S-F-I-T-L-L-E-E-A-V-A-C-G-A-R-Y-I-A-F-I-W-E-R-R-G-M-P-F-A-L-L-F-Y-D-V-I-N-R-E-W-K-P-Y-M-L-K-I-S-G-I-K-T-R-R-E-F-P-V-F-I-S-R-R-P-P-A-K-S-A-V-I-V-D-L-S-E-G-E-V-G-D-I-F-T-E-I-F-G-Y-P-I-L-Y-S-L-D-A-V-R-G-L-F-D-T-V-V-L-I-R-R-T-D-G-Y-L-V-E-L-L-G-S-D-L-G-P-R-A-S-S-I-R-I-K-K-V-V-Y-R-H-V"} +{"text": "### FUNCTION Involved in late/very late gene activation ### SEQUENCE -M-E-E-T-H-D-D-R-C-M-S-R-G-D-L-Y-A-Y-M-R-E-L-I-N-D-K-K-W-N-F-N-L-K-N-V-W-A-H-V-H-D-S-E-F-D-T-I-R-G-Y-I-R-D-H-L-D-D-A-I-I-I-H-K-D-L-R-Y-K-R-L-C-H-H-R-A-R-I-E-N-L-L-K-L-N-Q-S-L-K-K-E-Y-E-N-S-I-S-R-Y-N-G-A-A-Q-E-S-A-T-R-R-N-V-P-V-R-D-K-Q-R-R-A-V-A-A-A-A-D-R-I-D-R-K-A-T-R-H-C-K-S-N-R-E-R-T-V"} +{"text": "### FUNCTION Involved in late/very late gene activation ### SEQUENCE -M-N-N-C-A-T-F-S-M-P-H-S-N-A-T-N-H-T-T-L-S-H-P-V-C-N-N-N-A-N-C-F-T-R-S-E-L-Y-A-I-W-S-E-T-I-N-T-L-K-R-T-F-K-I-K-N-V-H-A-H-M-L-E-D-D-S-G-E-I-K-D-Y-I-R-A-N-L-S-R-F-T-V-I-T-G-K-C-S-K-R-K-V-C-H-H-D-K-R-I-A-R-T-L-H-L-E-K-N-L-V-D-E-Y-A-C-S-V-T-H-V-Y-S-A-P-K-W"} +{"text": "### FUNCTION Plays a role for multiplication of the virus in different cell types ### SEQUENCE -M-G-I-R-H-E-L-D-I-L-L-V-S-E-N-L-A-L-K-N-V-E-L-L-K-G-D-S-Y-G-C-T-I-N-I-K-V-N-Q-Q-K-K-L-D-F-I-I-I-L-R-P-D-W-T-E-V-R-N-V-K-K-I-N-M-V-C-N-G-V-V-I-D-T-T-L-I-K-K-S-F-Y-E-E-V-Y-S-S-S-V-T-V-F-Q-N-T-T-V-E-F-F-S-D-T-S-K-K-Y-K-E-E-Y-P-I-V-N-I-N-T-I-K-R-Y-Y-E-I-K-D-S-R-M-T-C-I-N-F-E-S-P-I-S-D-Y-D-Q-V-N-Y-L-K-D-Y-I-N-I-S-D-D-Y-Y-L-Y-D-A-C-D-D-C-I-I-S-S-D-D-D-D-D-N-D-N-A-D-D-D-E-E-D-D-D-E-V-N-D-I-E-D-D-Y-E"} +{"text": "### FUNCTION Potential transcriptional regulator that is required to activate expression of a number of early meiotic genes including HOP1 ### SEQUENCE -M-S-F-E-E-E-E-K-N-K-V-T-C-T-Q-D-F-L-R-Q-Y-F-V-S-E-S-V-S-I-Q-F-G-L-N-N-K-T-V-K-R-I-N-E-D-E-F-D-K-A-I-N-C-I-M-A-W-T-R-Y-P-E-A-V-V-K-R-T-A-S-T-Y-L-L-S-D-S-C-K-K-S-T-T-L-S-L-P-F-V-L-D-D-A-L-C-I-P-K-G-V-E-S-N-N-N-D-T-S-L-L-Y-S-D-T-L-Y-G-D-D-S-L-I-R-R-N-E-Q-V-R-D-E-L-E-E-E-L-S-F-T-L-L-R-S-E-I-N-E-I-K-P-I-S-S-S-S-T-P-Q-I-L-Q-S-D-Y-S-A-V-M-Q-E-T-Q-A-S-N-G-S-I-F-Q-F-S-S-P"} +{"text": "### FUNCTION Potential transcriptional regulator that is required to activate expression of a number of early meiotic genes including HOP1 ### SEQUENCE -M-S-T-N-K-E-E-E-H-Q-I-V-C-T-Q-D-F-L-R-Q-Y-Y-V-S-E-S-V-S-I-Q-F-G-L-N-N-K-T-I-R-T-I-N-E-E-E-F-N-N-A-A-M-C-I-M-T-R-T-N-Y-P-E-S-T-L-K-R-S-A-S-T-Y-L-L-N-S-Y-H-K-K-P-A-T-L-S-L-P-F-V-F-G-D-T-I-N-L-S-E-D-M-E-D-N-N-E-N-N-L-L-Y-S-D-T-L-Y-G-D-D-S-L-T-Q-R-G-D-Q-V-V-Y-K-I-D-T-Q-E-E-D-S-S-F-T-L-L-Q-S-E-A-N-E-T-R-P-L-S-S-S-S-T-P-Q-I-L-Q-S-D-Y-S-V-V-M-Q-E-G-Q-T-S-N-G-S-I-F-Q-F-S-S-P"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-F-E-K-T-N-R-M-N-L-L-F-D-F-Y-Q-E-L-L-T-T-K-Q-K-S-Y-V-S-F-Y-Y-L-D-D-Y-S-L-G-E-I-A-E-E-F-E-V-S-R-Q-A-I-Y-D-N-I-K-R-T-E-E-S-L-E-K-Y-E-E-K-L-G-M-L-R-K-Y-Q-Q-R-E-K-L-F-D-Q-L-E-A-Q-L-T-K-K-N-F-L-D-E-Q-V-K-D-T-L-E-Q-L-K-N-I-D"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-E-I-T-D-V-R-L-R-R-V-E-T-D-G-R-M-K-A-I-S-S-I-T-I-D-G-E-F-V-I-H-D-I-R-V-I-D-G-N-E-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-G-T-R-A-K-I-Q-E-A-V-L-A-A-Y-E-V-A-D-E-P-A-V-N-E-E-S-S-A-D-E-S-V-V-E-E-N"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-A-I-F-D-S-V-S-N-M-E-E-Q-I-G-E-L-Y-Q-Q-L-G-D-L-K-T-N-L-G-E-M-L-E-E-N-N-R-L-N-L-E-N-E-H-L-R-R-R-L-S-L-T-D-E-V-A-P-E-P-V-A-E-E-E-A-V-H-G-V-M-A-P-N-R-K-E-A-M-Q-Q-M-I-E-L-G-E-G-Y-D-N-L-V-Q-L-Y-K-E-G-F-H-V-C-N-V-H-F-G-S-P-R-G-N-D-E-D-C-L-F-C-L-S-L-L-N-K-K"} +{"text": "### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-I-T-K-N-Y-L-I-D-K-I-H-D-K-L-N-C-L-S-K-E-D-V-K-D-S-V-D-L-I-L-D-Y-L-N-E-S-L-K-K-Q-K-R-I-E-I-R-N-F-G-N-F-S-I-R-K-R-K-F-P-E-S-E-K-F-Y-N-T-V-Y-Y-R-M-P-K-N-L-F-K-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-C-P-Q-P-H-A-D-H-A-I-T-R-G-D-T-G-A-A-G-G-R-N-W-S-G-P-F-R-K-T-P-G-R-L-V-G-M-T-L-I-R-A-Y-Q-L-T-L-S-S-F-I-G-N-S-C-R-H-L-P-T-C-S-E-Y-G-F-E-A-I-A-R-Y-G-L-W-A-G-G-W-L-T-L-F-R-V-V-R-C-G-P-G-G-T-H-G-F-D-P-V-P-D-S-L-A-P-R-Q-R-W-Y-T-P-W-R-Y-W-Q-P-R-R-K-D-A"} +{"text": "### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-C-R-C-S-A-D-S-S-P-V-D-V-K-D-I-L-N-R-L-K-S-L-S-A-A-E-E-F-F-E-A-L-G-G-P-Y-D-P-K-V-L-D-V-S-R-L-H-I-M-K-R-M-G-Q-Y-L-A-A-E-D-F-S-H-L-P-D-R-V-I-A-A-R-A-R-A-I-L-E-R-A-Y-C-D-F-A-T-S-A-P-L-S-H-R-V-F-K-V-L-K-D-H-N-P-N-R-P-V-T-P-G-R-T-V-V-P-L-D-S-F-L-K-P-F-E-K-K"} +{"text": "### FUNCTION Required for tapetum and pollen development ### SEQUENCE -M-V-R-V-G-A-A-A-A-V-L-V-L-A-A-A-A-A-A-M-A-A-E-P-P-T-D-D-G-A-V-R-V-A-A-G-L-T-K-C-V-S-G-C-G-S-K-V-T-S-C-L-L-G-C-Y-G-G-G-G-G-A-A-A-A-A-T-A-M-P-F-C-V-I-G-C-T-S-D-V-L-S-C-A-T-G-C-S-T-S-L"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-I-I-Y-K-D-I-V-S-G-D-E-M-F-S-D-A-Y-K-M-K-V-L-D-D-Y-F-Y-E-L-E-G-K-I-T-T-E-K-G-G-I-D-E-S-A-I-G-G-N-A-S-A-E-D-A-V-E-G-L-E-E-S-G-T-T-G-C-N-I-V-I-A-Q-R-L-Q-E-T-Q-F-T-K-A-Q-Y-K-V-Y-I-K-D-Y-S-K-K-V-L-E-Y-L-T-K-N-K-P-E-R-V-D-G-F-K-A-A-S-A-A-G-M-K-R-V-M-G-N-F-K-N-W-Q-F-F-T-G-E-K-M-D-Q-D-G-M-V-A-L-M-D-Y-R-E-D-G-K-T-P-Y-M-L-F-F-K-D-G-L-E-E-E-K-F"} +{"text": "### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-I-F-K-D-A-F-T-D-D-E-L-A-S-D-S-F-P-M-K-L-V-D-G-L-I-W-E-F-K-G-R-Q-V-V-R-R-E-G-E-I-Q-L-A-G-A-N-P-S-T-E-G-E-D-G-D-E-G-S-E-E-C-V-E-R-G-I-D-F-V-L-N-H-R-L-Q-E-M-N-C-Y-E-D-L-A-T-F-K-S-Y-C-K-S-F-M-K-K-V-V-E-L-M-Q-K-N-G-K-S-E-A-E-I-S-E-F-K-R-K-I-Q-A-W-V-V-S-L-L-S-K-D-R-F-K-Q-L-Q-F-F-I-G-E-R-M-A-E-G-Q-G-E-G-Q-V-A-V-V-E-Y-R-D-E-E-E-G-E-V-P-Y-L-M-L-V-K-E-A-L-V-E-E-K-Q"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-A-K-T-I-T-I-S-E-E-A-Y-R-L-L-L-S-E-K-R-E-G-E-S-F-S-D-V-I-I-R-L-V-K-S-S-R-K-N-I-M-D-Y-A-G-I-W-G-D-M-N-D-E-E-V-N-K-L-F-E-D-L-K-K-M-W-E-R-W-N-V-N-A"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-K-T-I-M-I-R-D-D-V-Y-K-K-L-L-E-I-K-G-D-K-S-F-S-E-I-I-E-E-L-I-E-E-S-L-S-V-R-R-K-K-I-E-K-Y-F-G-I-L-N-E-E-E-A-R-G-L-A-K-E-I-E-E-M-R-K-R-T-D-E-D-I-A-R-K-L-S-N-Y"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-L-I-H-R-I-E-I-V-F-T-S-S-R-D-A-P-L-R-V-R-T-F-L-N-E-L-T-Y-V-F-P-N-S-I-K-I-N-R-G-R-Q-S-L-K-D-I-I-A-K-S-I-Y-L-N-S-K-Y-L-V-I-I-D-V-I-K-G-N-P-G-R-F-R-V-Y-D-L-T-S-K-M-L-K-Y-N-F-I-I-Y-G-V-T-L-L-T-E-L-K-L-H-R-T-L-I-K-R-G-C-I-G-K-I-E-D-Q-K-I-K-N-M-L-I-D-L-G-Y-I-Y-I-E-N-C-D-V-Y-A-N-G-D-Y-I-I-K-D-N-N-Y-V-F-E-L-K-F-T-K-D-D-K-I-L-G-P-V-I-R-F-Q-L-Y-D-R-N-K-N-I-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-M-R-R-I-L-L-K-S-I-K-F-Y-R-I-Y-L-S-P-L-K-R-N-A-C-C-K-F-I-P-T-C-S-Q-Y-A-I-D-A-I-E-K-Y-G-A-L-K-G-S-F-M-A-V-K-R-I-L-R-C-N-P-F-S-K-G-G-Y-D-P-V-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle ### SEQUENCE -M-E-E-R-I-Y-L-S-M-L-L-S-T-Y-G-S-L-L-T-E-K-Q-V-N-V-M-R-L-Y-Y-D-D-D-L-S-M-P-E-I-A-E-L-N-N-T-T-R-Q-A-I-H-D-L-I-K-R-C-H-K-M-L-L-N-Y-E-N-K-L-K-L-V-E-K-Y-K-R-N-E-D-I-K-K-D-I-K-D-K-L-Y-I-L-K-D-K-I-Q-D-K-D-N-V-Q-L-I-D-E-I-E-K-D-I-N-S-F-S-I"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-D-K-K-E-L-F-D-A-L-D-D-F-S-Q-Q-L-L-V-T-L-A-D-V-E-A-I-K-K-N-L-K-S-L-V-E-E-N-T-A-L-R-L-E-N-S-K-L-R-E-R-L-G-E-V-E-A-D-A-P-V-K-A-K-H-V-R-E-S-V-R-R-I-Y-R-D-G-F-H-V-C-N-D-F-Y-G-Q-R-R-E-Q-D-E-E-C-M-F-C-D-E-L-L-Y-R-E"} +{"text": "### FUNCTION Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region ### SEQUENCE -M-H-N-M-S-D-I-I-E-Q-Y-I-K-R-L-F-E-E-S-N-E-D-V-V-E-I-Q-R-A-N-I-A-Q-R-F-D-C-V-P-S-Q-L-N-Y-V-I-K-T-R-F-T-N-E-H-G-Y-E-I-E-S-K-R-G-G-G-G-Y-I-R-I-T-K-I-E-N-K-D-A-T-G-Y-I-N-H-L-L-Q-L-I-G-P-S-I-S-Q-Q-Q-A-Y-Y-I-I-D-G-L-L-D-K-M-L-I-N-E-R-E-A-K-M-I-Q-A-V-I-D-R-E-T-L-S-M-D-M-V-S-R-D-I-I-R-A-N-I-L-K-R-L-L-P-V-I-N-Y-Y"} +{"text": "### FUNCTION Could be involved in septation ### SEQUENCE -M-K-V-T-D-V-R-L-R-K-I-Q-T-D-G-R-M-K-A-L-V-S-I-T-L-D-E-A-F-V-I-H-D-L-R-V-I-E-G-N-S-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-D-M-R-Q-E-I-Q-D-A-V-M-K-V-Y-D-E-T-D-E-V-V-P-D-K-N-A-T-S-E-D-S-E-E-A"} +{"text": "### FUNCTION Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host ### SEQUENCE -M-N-Q-H-V-K-V-T-F-D-F-T-N-Y-N-Y-G-T-Y-D-L-A-V-P-A-Y-L-P-I-K-N-L-I-A-L-V-L-D-S-L-D-I-S-I-F-D-V-N-T-Q-I-K-V-M-T-K-G-Q-L-L-V-E-N-D-R-L-I-D-Y-Q-I-A-D-G-D-I-L-K-L-L"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-E-L-F-D-A-F-D-G-F-S-Q-N-L-M-V-T-L-A-E-I-E-A-M-K-K-Q-V-Q-S-L-V-E-E-N-T-I-L-R-L-E-N-T-K-L-R-E-R-L-S-H-L-E-H-E-T-V-A-K-N-P-S-K-Q-R-K-D-H-L-E-G-I-Y-D-E-G-F-H-I-C-N-F-F-Y-G-Q-R-R-E-N-D-E-E-C-M-F-C-R-E-L-L-D-R-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-F-Y-E-R-T-V-D-L-G-L-R-A-Y-K-L-T-L-S-P-L-I-G-R-Q-C-R-F-T-P-S-C-S-E-Y-T-A-A-A-L-K-D-H-G-P-L-K-G-S-W-L-G-L-R-R-I-C-R-C-N-P-F-G-G-S-G-Y-D-P-P-P-P-R-H-Q-P-R-K-W-K-C-E-E"} +{"text": "### FUNCTION May form complexes with phosphorylated ligands by interfering with kinases and their effectors ### SEQUENCE -M-A-R-F-V-D-P-L-V-V-G-R-V-I-G-E-V-V-D-L-F-V-P-S-I-S-M-T-A-A-Y-G-D-R-D-I-S-N-G-C-L-V-R-P-S-A-A-D-Y-P-P-L-V-R-I-S-G-R-R-N-D-L-Y-T-L-I-M-T-D-P-D-A-P-S-P-S-D-P-S-M-R-E-F-L-H-W-I-V-V-N-I-P-G-G-T-D-A-S-K-G-E-E-M-V-E-Y-M-G-P-R-P-T-V-G-I-H-R-Y-V-L-V-L-Y-E-Q-K-A-R-F-V-D-G-A-L-M-P-P-A-D-R-P-N-F-N-T-R-A-F-A-A-Y-H-Q-L-G-L-P-T-A-V-V-H-F-N-S-Q-R-E-P-A-N-R-R-R"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-V-L-V-K-A-V-H-G-Y-Q-R-W-I-S-P-A-L-P-P-A-C-R-Y-Y-P-T-C-S-N-Y-M-V-Q-A-I-E-K-H-G-P-A-K-G-L-A-M-G-T-A-R-I-L-R-C-H-P-F-C-Q-P-G-Y-D-L-V-P-D-H-F-S-L-R-R-N-W-A-E-P-E-K-E-E-D-S-N"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-E-I-E-K-T-N-R-M-N-T-L-F-E-F-Y-A-T-L-L-T-D-K-Q-M-N-Y-I-E-L-Y-Y-A-D-D-Y-S-L-A-E-I-A-E-E-F-N-I-S-R-Q-A-V-Y-D-N-I-K-R-T-E-K-V-L-E-S-Y-E-E-K-L-H-L-F-S-N-Y-V-V-R-N-Q-L-L-E-E-L-M-K-K-Y-S-T-D-Q-Y-L-I-T-K-L-Q-E-I-Q-Q-I-D-E-E-E-F"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-T-Q-Y-N-K-L-R-I-E-W-D-C-R-R-G-M-L-E-L-D-N-V-I-M-P-F-Y-R-Q-H-F-D-A-L-S-D-T-Q-K-D-T-F-I-R-L-L-A-C-S-D-L-Q-L-F-S-W-F-F-N-R-G-M-A-T-D-P-Q-L-Q-Q-M-V-D-Y-I-Q-K-T-L-K-L-T-D"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-K-L-A-F-V-F-R-S-T-P-F-G-R-A-S-T-R-E-G-L-D-A-L-L-A-A-T-A-F-C-D-E-Q-D-I-A-V-F-F-L-D-D-G-V-F-S-L-L-N-H-Q-D-P-A-Q-I-L-Q-K-D-V-V-N-M-F-K-L-L-D-L-Y-D-I-E-Q-R-Y-I-C-L-E-S-L-A-T-A-K-M-T-A-S-D-C-I-I-T-C-E-K-M-A-R-A-A-L-L-T-L-L-G-K-A-E-R-V-L-T-F"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-F-C-E-Y-L-K-Q-E-S-E-G-L-D-F-Q-L-Y-P-G-E-L-G-K-R-I-F-D-S-I-S-K-Q-A-W-R-E-W-M-K-K-Q-T-M-L-V-N-E-K-K-L-N-M-M-N-A-D-H-R-Q-L-L-E-Q-E-M-V-N-F-L-F-E-G-K-D-V-H-I-E-G-Y-V-P-P-T-E"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-K-T-H-S-L-S-S-K-I-L-I-G-L-I-R-V-Y-Q-V-V-I-S-P-L-I-G-P-R-C-R-F-T-P-T-C-S-C-Y-G-I-E-A-V-K-T-H-G-A-I-K-G-S-W-L-T-L-K-R-I-L-K-C-H-P-L-N-A-G-G-Y-D-P-V-P-P-K-I-N-N-K-K-E-K-K"} +{"text": "### FUNCTION Microtubule inner protein in cilia axoneme, which is required for motile cilia beating ### SEQUENCE -M-S-A-E-K-M-T-K-L-E-E-N-L-Q-R-A-V-A-L-K-K-T-V-D-R-W-R-N-F-H-I-H-C-M-W-Q-T-T-L-D-Q-R-R-N-L-F-A-A-L-R-M-K-D-T-K-E-Q-E-L-A-L-S-N-K-Q-L-L-V-V-R-Q-A-A-L-H-E-L-F-E-K-E-Y-Q-Q-Y-Q-Q-E-L-N-Q-M-G-K-A-F-Y-E-E-R-L"} +{"text": "### FUNCTION Plays a role for multiplication of the virus in different cell types ### SEQUENCE -M-G-I-T-H-E-L-D-I-F-V-T-N-E-D-L-A-L-K-N-V-E-L-F-K-G-N-S-Y-G-C-F-I-N-L-K-V-K-E-E-K-K-F-N-I-I-F-V-L-K-P-D-W-S-E-V-D-K-V-K-P-I-R-M-I-V-N-N-N-S-V-D-V-E-K-V-S-E-S-L-Y-Q-V-V-Y-S-A-S-F-S-I-N-S-D-S-Y-V-K-V-F-S-D-N-P-D-K-Y-K-H-M-Y-P-T-V-T-I-N-V-P-K-K-K-F-K-V-V-D-Q-G-N-T-Y-M-F-I-Q-S-P-I-D-D-C-D-K-E-Q-F-L-K-N-E-F-E-Y-Y-D-E-E-N-D-F-D-D-Y-E-E-Y-V-K-N-R-N-D-S-F-D-D-Y"} +{"text": "### FUNCTION Plays a central role in the packaging of viral DNA into phage procapsid, which occurs in the late stage of infection The protein VP5 can interact with the replicative complex after the completion of one round of DNA synthesis When protein VP5 is bound to the replicative form, the complex becomes accessible to procapsid and serves as a DNA packaging apparatus ### SEQUENCE -M-Q-L-K-V-F-S-I-R-D-S-K-T-G-V-Y-G-T-P-F-Y-Q-H-T-H-G-Q-A-E-R-S-F-Q-Q-L-A-K-D-P-Q-S-T-V-A-N-H-P-E-D-F-D-L-F-H-L-G-E-Y-D-D-Q-T-G-K-L-T-P-L-D-T-P-E-H-C-V-K-A-I-D-L-I-K-Q-Q"} +{"text": "### FUNCTION Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels ### SEQUENCE -M-G-D-L-P-G-L-V-R-L-S-I-A-L-R-I-Q-P-N-D-G-P-V-F-Y-K-V-D-G-Q-R-F-G-Q-N-R-T-I-K-L-L-T-G-S-S-Y-K-V-E-V-K-I-K-P-S-T-L-Q-V-E-N-I-S-I-G-G-V-L-V-P-L-E-L-K-S-K-E-P-D-G-D-R-V-V-Y-T-G-T-Y-D-T-E-G-V-T-P-T-K-S-G-E-R-Q-P-I-Q-I-T-M-P-F-A-D-I-G-T-F-E-T-V-W-Q-V-K-F-Y-N-Y-H-K-R-D-H-C-Q-W-G-S-P-F-S-V-I-E-Y-E-C-K-P-N-E-T-R-S-L-M-W-V-N-K-E-S-F-L"} +{"text": "### FUNCTION May play a role in ciliary assembly ### SEQUENCE -M-T-S-L-F-A-Q-E-I-R-L-S-K-R-H-E-E-I-V-S-Q-R-L-M-L-L-Q-Q-M-E-N-K-L-G-D-Q-H-T-E-K-A-S-Q-L-Q-T-V-E-T-A-F-K-R-N-L-S-L-L-K-D-I-E-A-A-E-K-S-L-Q-T-R-I-H-P-L-P-R-P-E-V-V-S-L-E-T-R-Y-W-A-S-V-E-E-Y-I-P-K-W-E-Q-F-L-L-G-R-A-P-Y-P-F-A-V-E-N-Q-N-E-A-E-N-T-I-Q-N-E-A-Q-R"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-S-Q-S-L-L-I-I-S-R-Q-S-P-W-S-G-P-S-A-R-E-A-L-D-I-A-L-A-G-G-A-F-D-L-P-V-G-M-L-F-L-D-D-G-A-F-Q-L-A-P-G-Q-H-P-A-H-L-Q-Q-K-D-L-Q-A-N-L-Q-A-L-P-M-F-G-V-D-D-L-Y-V-S-A-R-S-L-R-E-R-G-L-A-E-E-R-L-A-L-A-V-E-V-L-D-D-Q-A-L-R-D-L-L-Q-R-Y-D-Q-V-I-T-L"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-F-L-L-I-G-L-I-R-F-Y-Q-Y-A-I-S-P-L-I-G-P-R-C-R-F-Y-P-S-C-S-H-Y-T-L-E-A-I-R-V-H-G-A-L-R-G-G-Y-L-G-A-R-R-L-L-R-C-H-P-W-H-P-G-G-Y-D-P-V-P-E-R-Q-E-Q-A-C-A-C-H-R-T-A-K-P-G-K"} +{"text": "### FUNCTION Required for the association between the dense viroplasm and the viral membranes to form the mature virion ### SEQUENCE -M-D-D-I-D-Y-I-D-D-I-N-E-D-S-I-N-H-M-L-S-T-L-A-N-V-R-D-P-E-F-S-A-T-I-S-L-M-Q-E-V-L-K-I-I-N-S-R-I-I-E-I-D-K-K-Y-K-K-N-N-R-N-I-N-S-M-N-N-A-S-S-R-V-S-Y"} +{"text": "### FUNCTION Involved in late/very late gene activation ### SEQUENCE -M-C-L-T-R-S-D-V-Y-A-Y-V-R-E-T-I-N-K-R-K-H-E-V-D-V-S-N-V-L-A-H-I-F-E-F-D-F-Q-E-H-V-E-Y-I-R-A-N-I-D-K-A-L-I-T-V-G-G-E-Q-P-Y-C-K-R-L-S-Y-H-I-K-R-I-N-K-I-F-N-L-I-T-S-L-E-T-E-Y-K-A-A-V-S-K-Y-D-G-D-K-H-H-Y-E-R-S-N"} +{"text": "### FUNCTION Inhibits the synthesis of glutamine synthetase II ### SEQUENCE -M-P-T-G-F-H-R-E-S-A-T-I-Y-Q-F-P-V-K-A-I-R-N-A-N-R-F-E-R-A-R-L-M-E-R-E-A-A-E-V-C-D-A-A-L-D-S-C-W-Y-H-D-E-A-V-R-E-S-D-R-P-T-K-S"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-R-F-F-I-G-C-I-R-L-Y-Q-K-F-I-S-P-L-T-P-P-T-C-R-F-Y-P-T-C-S-H-Y-G-I-E-A-I-Q-R-F-G-V-L-K-G-G-W-L-T-I-K-R-I-S-K-C-H-P-F-H-R-G-G-I-D-P-V-P-E-K-K-Q-E-K"} +{"text": "### FUNCTION Might take part in the signal recognition particle pathway This is inferred from the conservation of its genetic proximity to ftsY/ffh May be a regulatory protein ### SEQUENCE -M-L-D-K-T-L-R-M-N-Y-L-F-D-F-Y-Q-S-L-L-T-E-K-Q-R-K-Y-M-S-L-Y-Y-L-D-D-F-S-L-G-E-I-A-E-E-F-D-V-S-R-Q-A-V-Y-D-N-I-K-R-T-E-A-M-L-E-E-Y-E-E-K-L-S-L-L-A-K-F-E-K-R-S-E-I-L-Q-Q-L-K-E-A-V-D-K-Q-A-T-S-E-E-L-M-A-L-L-E-S-L-D-T-L-E"} +{"text": "### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-N-K-K-A-I-F-T-Q-V-S-Q-L-E-E-R-I-G-E-L-H-R-E-L-G-G-L-K-E-Q-L-A-Y-L-I-E-E-N-H-F-L-T-I-E-N-E-H-L-R-E-R-L-G-E-P-E-L-E-E-T-E-E-K-E-Q-V-T-K-E-R-K-P-F-V-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-N-T-H-Y-G-S-L-R-K-N-G-E-D-C-L-F-C-L-S-F-L-N-Q-D"} +{"text": "### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-N-K-V-A-W-V-F-H-T-P-P-H-G-S-T-A-G-R-E-G-L-D-A-I-L-A-T-S-A-Y-S-E-E-Q-A-L-F-F-V-G-E-G-V-L-Q-L-V-N-H-Q-H-P-E-S-I-L-S-R-D-Y-I-S-A-F-K-L-L-D-L-Y-D-I-E-A-R-Y-V-C-Q-Q-S-L-V-S-W-G-L-S-E-Q-D-L-L-I-E-V-E-V-V-D-A-Q-A-L-A-Q-L-L-H-H-Y-D-Q-L-L-T-F"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-A-T-P-L-S-P-F-S-W-L-A-I-G-I-V-K-L-Y-Q-W-F-I-S-P-L-I-G-P-R-C-R-F-T-P-T-C-S-T-Y-A-I-E-A-L-R-A-H-G-F-I-K-G-C-W-L-S-T-K-R-L-L-K-C-H-P-L-N-E-G-G-F-D-P-V-P-P-V-Q-K-Q-D-R-D-K"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-T-G-P-A-R-S-G-A-A-I-R-G-A-G-R-T-V-A-R-G-L-I-F-L-I-Q-L-Y-R-H-M-V-S-P-L-R-P-A-T-C-R-F-V-P-T-C-S-Q-Y-A-V-D-A-L-D-E-Y-G-L-I-R-G-S-W-L-A-A-A-R-L-A-K-C-G-P-W-H-Q-G-G-W-D-P-I-P-E-R-P-G-C-R-V-N-C-Q-D-A-S-D-A-W-A-V-R-A-T-R-G-E-S-G-S-L-V"} +{"text": "### FUNCTION Probable cyclin-dependent protein kinase inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle ### SEQUENCE -M-V-L-L-S-F-S-R-Y-C-D-T-I-T-M-D-Y-E-E-N-S-I-E-G-T-S-G-Y-V-E-P-I-T-P-M-I-S-K-G-D-S-G-I-I-A-I-S-P-L-C-D-H-Y-N-N-H-M-R-I-D-S-L-T-T-C-S-D-E-E-I-I-E-S-L-Y-Q-N-I-F-S-I-V-L-C-L-Q-T-E-E-S-G-Y-G-S-H-T-P-V-S-A-A-C-P-G-A-P-M-K-L-T-K-L-S-R-N-I-D-P-G-F-Q-R-K-L-F"} +{"text": "### FUNCTION Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors ### SEQUENCE -M-A-K-Q-D-P-T-S-S-N-T-M-L-P-L-V-G-S-E-F-V-R-P-Q-P-L-D-L-T-I-T-G-D-T-V-K-D-A-T-G-N-K-V-F-K-V-K-T-P-L-F-G-L-H-N-K-R-I-L-V-D-P-N-D-S-P-I-V-T-M-K-M-K-V-T-S-K-H-D-R-W-Q-V-Y-R-G-S-D-L-D-D-K-I-F-T-V-K-R-S-S-T-V-Q-L-K-T-R-V-E-V-F-L-K-H-N-Q-T-R-E-S-S-C-D-F-T-I-K-G-R-F-M-K-R-A-C-T-I-Y-V-A-D-S-T-K-I-I-A-Q-V-Y-E-G-H-E-R-L-V-A-T-I-Y-P-N-V-D-Y-A-F-I-V-T-L-I-F-I-F-D-L-I-N-M-G-T-G-I"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-S-R-N-T-S-V-A-L-G-P-H-F-T-S-F-I-D-A-Q-V-Q-G-G-R-Y-G-T-A-S-D-V-V-R-A-G-L-R-L-L-E-E-H-E-T-K-V-K-A-L-Q-D-A-L-N-V-R-H-Q-S-G-E-P-R-P-F-D-S-E-V-F-L-S-R-M-H-T-Q-H-G"} +{"text": "### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-Q-R-I-I-F-C-E-Y-E-Q-R-D-T-E-G-L-D-F-V-P-Y-P-G-E-L-G-Q-K-I-F-A-C-I-G-K-V-G-W-A-A-W-L-V-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-N-P-S-H-R-A-F-L-E-E-E-L-N-K-F-L-F-E-R-R-V-A-K-P-E-G-Y-I-E-P-D-A"} +{"text": "### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-C-Y-C-G-C-Q-R-A-T-A-E-E-P-T-M-D-E-P-A-E-L-N-K-L-R-W-R-S-R-R-G-M-R-E-L-D-H-L-F-D-R-Y-L-S-H-R-W-A-Q-A-S-E-A-E-R-G-V-F-L-R-F-L-D-C-E-D-D-K-L-W-R-W-L-M-G-Y-E-V-C-Q-D-A-S-F-A-A-L-I-V-T-I-R-A-L-P-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-T-S-W-I-K-I-F-F-Q-G-M-I-H-L-Y-R-W-T-I-S-P-L-L-G-S-P-C-R-F-F-P-S-C-S-E-Y-A-L-V-A-L-K-K-H-P-L-K-R-S-L-F-L-I-A-N-R-L-L-K-C-G-P-W-H-I-G-G-I-D-L-V-P-G-T-S-I-E-E-Y-L-E-S-P-D-D-K-N-V-P-P-D-Q-E-T-V"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-I-C-L-K-I-L-R-F-Y-Q-K-F-L-S-P-L-K-P-A-A-C-R-Y-Y-P-S-C-S-E-Y-A-L-W-Q-F-Q-K-K-N-F-F-L-A-F-F-S-T-F-F-R-I-L-R-C-N-P-F-F-K-G-G-F-D-Y-P-R-V-S-K-N-F-Y-P-I-N-L-C-F-K-P-I-F-L-A-E-K-Q-L-C-F-L-Y-I-P-Y-K-N-K-S-F-Y-L-I-K-I-I-F-K-R-T-N-Q"} +{"text": "### FUNCTION Might take part in the signal recognition particle ### SEQUENCE -M-L-N-K-N-K-R-W-Y-L-I-A-L-Y-D-I-Y-Q-G-L-L-T-T-K-Q-C-E-Y-F-N-L-H-Y-F-K-D-L-S-F-S-E-I-A-E-L-K-E-I-S-K-S-A-I-S-D-C-L-N-K-V-C-D-Q-L-L-K-Y-E-Q-A-L-L-I-Y-E-K-N-K-K-R-N-D-L-Y-T-L-I-N-D-S-E-L-V-K-K-L-K-D-I"} +{"text": "### FUNCTION Plays a role for multiplication of the virus in different cell types ### SEQUENCE -M-G-I-T-H-E-F-H-I-F-L-V-D-E-N-V-S-L-K-S-V-S-L-L-K-G-D-S-Y-G-C-N-I-H-L-K-N-S-E-C-K-Y-I-T-F-I-L-V-L-E-P-D-W-S-E-I-A-E-A-K-P-I-R-I-R-L-N-G-K-K-M-R-T-Q-L-L-T-K-T-L-M-S-I-I-Y-K-A-V-I-Y-V-E-E-N-A-L-V-Q-F-Y-S-D-T-D-R-L-Y-T-D-M-Y-P-T-F-L-I-D-M-D-K-Q-H-Y-H-I-L-D-N-G-Y-T-Y-T-Y-I-D-S-F-I-S-E-C-D-K-Q-R-Y-L-T-S-D-I-G-E-N-G-Y-E-D-S-T-E-E-E-D-N-E-E-D-T-D-G-V-C-L-Y-C-L-E-E-E-E-E-E-D-E-D-E-D-E-D-E-D-E-D-E-E-E"} +{"text": "### FUNCTION Plays a role for multiplication of the virus in different cell types ### SEQUENCE -M-G-I-Q-H-K-L-D-V-F-I-V-S-E-N-I-A-I-K-D-A-N-L-L-N-G-D-S-Y-G-C-T-I-K-L-K-L-N-T-K-K-S-V-R-F-V-V-L-L-E-P-E-W-I-D-E-I-K-P-M-Y-M-K-L-N-G-V-S-V-D-L-K-L-D-Y-K-D-A-I-K-R-I-Y-S-V-D-L-V-L-Y-S-D-S-V-I-H-L-F-S-D-T-D-E-R-Y-T-C-E-Y-P-T-I-K-V-N-M-I-K-K-Y-Y-H-V-Q-H-R-G-T-T-C-V-H-I-E-S-P-I-N-V-S-D-K-Y-W-F-M-K-R-D-G-W-Y-V-D-R-T-H-S"} +{"text": "### FUNCTION Plays a role for multiplication of the virus in different cell types ### SEQUENCE -M-G-I-T-H-E-L-D-I-F-V-T-N-E-D-L-A-L-K-N-I-E-L-F-K-G-N-S-Y-G-C-F-I-N-L-K-V-K-E-E-K-R-F-N-M-I-F-V-L-R-P-D-W-S-E-I-D-S-V-K-P-I-R-M-T-V-N-N-N-H-V-D-V-E-K-V-S-E-S-I-H-E-V-V-Y-S-A-S-F-L-I-S-F-N-S-L-V-K-V-F-S-D-D-P-D-K-Y-K-N-V-Y-P-T-V-T-I-N-V-P-K-K-K-F-K-V-V-D-Q-G-N-T-Y-M-F-I-Q-Y-P-I-D-D-C-D-K-E-R-F-L-K-D-E-F-K-Y-C-D-N-E-Y-D-Q-Y-N-D-C-D-E"} +{"text": "### FUNCTION Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing , a mechanism of plant viral defense that limits the accumulation of viral RNAs Binds to dsRNAs without size specificity ### SEQUENCE -M-E-N-S-Q-T-G-V-L-C-P-N-R-C-Q-V-C-S-H-T-T-Y-I-R-E-S-S-G-Q-G-G-R-Q-A-C-R-F-T-R-F-V-T-Q-P-R-V-V-S-E-Q-G-I-Q-Y-R-S-W-L-S-D-R-G-F-P-A-T-L-L-S-T-S-G-G-L-S-T-T-I-R-G-H-G-V-A-V-T-I-Q-G-D-S-K-S-L-L-N-F-C-R-V-A-Y-D-V-F-H-H-P-V-V-Q-S-E-V-C-H-G-S-G-P-A-T-S-D-E-I-T-T-K-F"} +{"text": "### FUNCTION Modulates RecA activity ### SEQUENCE -M-T-V-V-L-D-T-L-V-A-V-R-R-T-A-M-D-L-L-A-R-R-E-H-G-R-V-E-L-T-R-K-L-R-Q-R-G-A-E-P-E-M-I-E-T-A-L-D-R-L-T-E-E-G-L-L-S-E-A-R-Y-L-E-S-F-V-S-Y-R-P-R-S-G-Y-G-P-A-R-I-R-E-E-L-S-Q-R-G-L-Q-R-A-D-I-D-L-A-L-R-E-C-G-I-S-W-Q-S-Q-L-E-D-T-W-R-R-K-F-S-G-H-L-P-I-D-A-K-E-R-A-K-Q-G-R-F-L-S-Y-R-G-F-S-M-D-M-I-S-R-L-L-S-G-R-D-L-D-D"} +{"text": "### FUNCTION Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors ### SEQUENCE -M-A-I-V-S-P-N-F-C-A-P-Y-P-I-E-L-G-I-V-R-K-V-M-T-L-T-D-G-N-F-A-V-T-D-V-N-G-N-L-L-F-K-V-K-E-P-L-F-S-I-S-D-K-R-I-L-L-D-A-Y-D-T-P-I-L-T-L-R-E-N-K-V-S-L-H-D-R-W-L-V-Y-R-G-K-S-T-D-Q-S-D-L-L-Y-T-L-K-R-S-S-M-I-Q-I-M-K-P-K-L-D-I-F-L-A-H-N-K-E-M-K-I-C-D-F-H-V-K-G-S-W-I-D-R-S-C-V-V-Y-A-G-K-S-D-A-I-V-A-Q-M-H-K-K-H-T-A-Q-S-I-L-I-G-K-S-N-F-S-V-T-V-Y-P-N-V-D-F-A-F-I-V-S-L-I-V-I-L-D-D-I-N-R-E-D-S-E-D"} +{"text": "### FUNCTION Chaperone involved in tail fiber assembly ### SEQUENCE -M-D-C-N-R-M-V-I-M-N-S-V-N-E-E-T-Y-Y-F-G-Q-R-K-L-A-W-F-A-G-S-M-K-K-D-Y-I-E-A-G-S-W-D-D-K-A-K-A-V-P-Y-S-V-Y-R-E-F-A-L-N-P-A-P-I-G-K-T-L-G-I-S-E-K-G-D-P-I-W-V-D-I-P-P-K-T-K-H-Q-L-I-T-E-A-E-D-K-K-S-G-L-M-Q-G-A-R-E-V-I-S-P-L-Q-D-A-I-D-L-E-M-A-T-Q-E-E-T-Q-K-L-T-A-W-K-R-Y-R-V-L-L-N-R-L-D-T-S-N-A-P-D-I-D-W-P-K-K-P-E"} +{"text": "### FUNCTION Essential for lysis of the bacterial cell wall by disrupting the cell membrane, thereby giving hydrolytic enzymes access to the cell wall ### SEQUENCE -M-S-E-F-C-K-P-L-L-D-I-L-R-H-Q-G-T-C-A-A-L-A-F-I-M-A-L-L-R-A-R-Y-H-R-K-D-F-Y-R-S-L-L-D-A-L-M-C-A-M-L-G-G-V-A-H-E-L-L-Q-F-L-G-L-K-A-D-Y-S-W-L-A-S-V-A-I-G-Y-L-G-V-D-R-I-G-N-W-L-K-K-K-T-G-K-L"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-H-I-H-R-T-R-I-V-I-T-S-S-R-D-P-S-I-R-T-R-N-F-L-N-V-L-T-F-V-L-P-D-S-V-K-I-T-R-G-K-K-S-K-I-E-I-F-E-R-A-I-N-L-G-A-L-Y-L-L-F-V-L-A-K-N-G-N-P-L-R-I-I-V-Y-D-L-E-S-L-S-I-K-Y-F-F-K-L-S-G-L-S-L-P-S-D-Y-N-V-S-L-N-Q-I-K-G-H-S-N-V-C-I-K-L-N-E-C-D-F-L-R-D-F-L-V-D-M-N-M-Y-N-L-T-N-N-C-D-V-V-V-N-S-R-L-I-H-T-N-I-C-E-L-L-F-M-L-T-T-K-N-I-K-F-L-K-M-I-L-E-A"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-E-V-I-E-V-V-Y-E-D-G-V-F-K-P-L-K-K-I-K-L-K-E-G-T-R-G-V-V-V-V-R-L-P-K-Q-I-S-E-I-A-K-K-Y-R-I-K-V-R-E-D-V-L-E-E-F-L-E-E-R-R"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-G-E-I-I-E-V-I-Y-E-N-G-I-L-K-P-L-K-K-L-P-F-K-E-G-E-K-L-I-V-E-V-K-S-T-N-K-E-K-L-L-E-E-L-K-G-S-I-K-L-G-K-K-V-T-I-T-R-I-L-E-L-E-D-E-V-W-S-S-I"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-S-K-T-I-T-I-A-D-D-V-Y-Y-E-L-V-K-M-K-G-N-K-S-F-S-E-L-L-R-E-L-I-G-K-K-K-K-G-N-L-D-I-L-M-I-A-F-G-T-M-S-E-E-E-V-K-E-F-K-K-K-I-K-E-V-E-E-W-I-N-S-W-T-P-V-S"} +{"text": "### FUNCTION May have a major role in the perfection of crystallization, involved either in the pore structure itself or in the organization of the pores within the linear array of terminal synthesizing complexes ### SEQUENCE -M-T-T-F-N-A-K-P-D-F-S-L-F-L-Q-A-L-S-W-E-I-D-D-Q-A-G-I-E-V-R-N-D-L-L-R-E-V-G-R-G-M-A-G-R-L-Q-P-P-L-C-N-T-I-H-Q-L-Q-I-E-L-N-A-L-L-G-M-I-N-W-G-Y-V-K-L-E-L-L-A-E-E-Q-A-M-R-I-V-H-E-D-L-P-Q-V-G-S-A-G-E-P-S-G-T-W-L-A-P-V-L-E-G-L-Y-G-R-W-I-T-S-Q-P-G-A-F-G-D-Y-V-V-T-R-D-V-D-A-E-D-L-N-S-V-P-T-Q-T-I-I-L-Y-M-R-T-R-S-N-S-N"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-L-L-I-M-L-I-R-F-Y-Q-R-Y-I-S-P-L-K-P-P-T-C-R-F-T-P-T-C-S-N-Y-F-I-Q-A-L-E-K-H-G-L-L-K-G-T-F-L-G-L-R-R-I-L-R-C-N-P-L-S-K-G-G-Y-D-P-V-P-E-E-F-S-F-K-P-R-R-R-W-S"} +{"text": "### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-E-N-T-P-K-L-N-V-P-K-R-K-P-T-G-E-M-R-V-V-Y-F-S-S-T-T-E-N-T-K-K-F-C-D-K-L-G-L-P-A-T-R-I-P-I-K-L-S-E-E-I-E-V-D-Y-D-Y-V-L-I-C-P-T-Y-A-G-G-L-D-D-F-K-G-S-V-P-R-Q-V-I-K-F-L-N-K-V-Q-N-R-E-H-C-V-G-V-V-A-S-G-N-T-N-F-G-E-T-F-G-L-A-G-H-V-L-R-A-K-L-H-V-P-L-L-H-V-F-E-L-I-G-T-K-Y-D-E-E-L-V-R-E-R-I-H-K-L-W-N-W-E-E"} +{"text": "### FUNCTION May regulate the expression of phage structural components with protein P13 ### SEQUENCE -M-N-P-T-I-A-K-I-T-C-P-L-C-G-N-D-E-A-T-V-H-R-Q-K-D-R-K-K-K-L-Y-Y-R-C-T-G-A-T-F-A-D-G-C-G-T-I-Q-C-T-G-A-S-G-Q-A-F-I-S-K-N-M-K-P-L-N-G-V-E-S-E-D-A-A-I-E-A-A-E-D-A-K-A-E-Q-V-K-P-N-K-K-R-S-F-L-D-F-L-V-D-D-E"} +{"text": "### FUNCTION Transcription factor that regulates expression of phage structural components with protein P14 ### SEQUENCE -M-N-R-D-I-Y-T-Q-I-E-T-V-G-V-L-E-K-R-V-E-K-A-G-T-F-E-L-K-A-A-A-M-A-L-A-K-A-Q-R-K-L-S-V-L-L-A-K-G-M-A-E-L-E-D-R-L-K-I-A-E-L-R-T-K"} +{"text": "### FUNCTION May be associated with TAP2 isoform activity ### SEQUENCE -M-S-L-L-W-T-P-Q-I-L-T-I-S-F-V-S-Y-I-L-S-L-F-P-S-P-F-P-S-C-Y-T-S-C-W-F-E-T-S-I-T-T-E-K-E-L-N-Q-Y-F-E-L-A-K-F-L-A"} +{"text": "### FUNCTION Probably involved in the biogenesis of the ribosome ### SEQUENCE -M-T-T-S-R-R-P-S-P-R-I-R-S-F-V-K-D-L-S-A-T-I-P-G-A-F-R-F-T-R-G-H-Y-S-M-E-E-L-A-R-E-A-I-I-R-G-A-D-R-I-V-V-V-G-E-R-R-G-N-P-G-I-I-R-V-Y-A-V-E-G-P-E-R-P-D-N-I-V-S-F-I-V-K-G-V-S-L-S-R-E-R-R-W-G-L-P-S-L-R-G-G-E-V-L-V-A-R-P-L-D-S-G-V-A-V-E-F-A-D-A-F-V-I-A-F-H-A-R-L-K-P-P-E-A-A-G-Y-V-E-A-V-I-E-S-L-D-A-R-T-V-A-V-T-F-R-Y-G-G-A-P-V-G-P-M-L-R-L-G-K-P-A-E-M-V-K-R-G-R-R-V"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-S-E-I-E-G-I-V-K-S-G-V-I-I-P-L-K-P-L-T-E-L-E-G-K-K-I-K-I-K-I-V-D-A-E-S-V-D-A-E-K-L-Y-S-Y-L-R-L-L-R-E-G-E-D-A-R-D-F-F-K-I"} +{"text": "### FUNCTION Possibly the antitoxin component of a type II toxin-antitoxin system ### SEQUENCE -M-S-K-V-I-R-V-R-Y-E-K-G-V-L-K-P-L-E-P-V-N-L-E-D-G-E-E-V-D-I-I-I-R-E-N-L-A-E-L-A-R-R-I-R-R-R-L-S-Q-E-R-E-E-P-S-E-I-L-S-R-E-R-S-R-L-A"} +{"text": "### FUNCTION Capsid protein self-assembles to form a bacilliform icosahedral capsid with a T=1 symmetry, about 50 nm length and 20 nm large ### SEQUENCE -M-A-N-R-R-Q-S-R-R-R-G-N-K-N-R-N-S-A-T-V-R-R-A-P-P-N-R-A-T-Q-S-S-S-G-K-V-K-F-V-K-W-I-A-A-S-P-T-K-L-I-P-H-I-G-E-N-E-T-S-Y-G-V-L-F-D-I-T-G-T-T-F-P-E-L-S-S-L-M-S-R-H-S-R-Y-R-V-L-S-L-G-A-R-I-V-P-Y-D-P-N-C-L-G-A-H-S-V-K-V-F-A-E-S-V-Y-D-S-S-A-T-P-T-V-P-S-V-H-Y-L-Q-S-N-G-C-R-V-V-P-A-N-K-Q-L-S-S-P-P-S-S-D-V-N-K-Y-Y-E-I-C-S-D-D-A-V-I-G-R-I-M-Y-A-W-N-G-P-G-L-S-T-A-R-V-G-F-C-S-F-E-V-Y-A-D-L-E-F-D-G-I-R-E"} +{"text": "### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-S-I-T-A-S-E-A-R-Q-N-L-F-P-L-I-E-Q-V-N-E-D-H-A-P-V-H-I-T-S-R-K-G-N-A-V-L-M-S-E-E-D-F-T-A-W-T-E-T-V-H-L-L-R-S-P-R-N-A-R-R-L-L-D-S-I-A-E-A-E-A-G-D-A-T-E-H-D-L-I-D-P-D-A-E-R-A"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-S-F-K-R-F-L-Q-Q-I-P-V-R-I-C-L-L-I-I-Y-L-Y-Q-W-L-I-S-P-L-L-G-S-C-C-R-F-F-P-S-C-S-H-Y-A-E-Q-A-L-K-S-H-G-F-L-M-G-C-W-L-S-I-K-R-I-G-K-C-G-P-W-H-P-G-G-I-D-M-V-P-K-T-A-L-Q-E-V-L-E-P-Y-Q-E-I-D-G-G-D-S-S-H-F-S-E"} +{"text": "### FUNCTION Functions as a specific chaperone for YopT ### SEQUENCE -M-Q-T-T-F-T-E-L-M-Q-Q-L-F-L-K-L-G-L-N-H-Q-V-N-E-N-D-V-Y-T-F-T-F-E-V-D-G-H-I-Q-V-L-I-A-C-Y-H-Q-Q-W-V-Q-L-F-S-E-L-G-A-D-L-P-T-N-D-N-L-F-G-E-H-W-P-A-H-V-Q-G-R-L-D-G-K-P-I-L-W-S-Q-Q-S-L-V-G-L-D-I-D-E-M-Q-A-W-L-E-R-F-I-D-D-I-E-Q-R-K-E-P-Q-N-T-K-F-Q-P-N-S-T-S-P-I-L-F-I"} +{"text": "### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-N-N-K-T-P-F-L-S-A-I-F-T-A-S-I-R-G-Y-Q-R-F-F-S-A-F-T-F-S-S-C-R-F-Y-P-T-C-S-N-Y-A-L-W-L-L-C-F-E-S-P-L-V-A-M-G-K-I-A-I-R-I-L-S-C-N-P-F-C-S-G-G-I-A-Y-P-T-T-R-L-K-R-P-S-L-L-Q-S-H-K-D-F-N-R-N-F-K-T-I-T-F-W-L-V-P-T-T-K-S-R-A-T-Y-Y-I-I-K-V"} +{"text": "### FUNCTION Might be involved in Fe ### SEQUENCE -M-T-L-N-E-A-I-K-D-K-T-Y-E-I-V-E-I-A-N-C-D-E-A-L-K-K-R-F-L-S-F-G-I-H-E-G-V-Q-C-T-L-L-H-S-S-M-K-K-A-T-L-S-I-K-I-N-R-I-Q-V-A-L-R-S-H-E-A-Q-Y-L-I-I-K-E-S-A-Q-E"} +{"text": "### FUNCTION Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors ### SEQUENCE -M-K-A-V-V-S-K-L-Y-C-S-S-M-E-E-V-M-V-V-R-R-R-P-H-V-V-N-G-G-G-F-V-V-T-D-Y-K-E-K-I-V-F-K-I-D-G-C-G-V-L-G-T-K-G-E-L-V-L-R-D-S-D-G-N-D-L-L-L-I-H-K-K-G-G-V-V-Q-A-L-S-I-H-N-K-W-K-G-Y-S-Y-D-Y-Q-G-S-P-K-P-V-F-T-L-R-D-P-K-H-S-C-F-S-I-T-S-S-I-R-I-S-V-G-P-G-N-C-Y-F-D-V-K-G-Y-F-P-D-R-D-C-S-I-V-D-S-K-G-N-V-I-A-Q-V-K-E-W-I-G-S-R-D-I-Y-K-V-V-T-K-P-S-V-D-K-A-F-V-F-G-V-I-A-V-L-D-Y-I-Y-G-E-S-T-S-C"} +{"text": "### FUNCTION Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors ### SEQUENCE -M-T-K-V-H-P-K-F-P-S-T-C-E-E-S-L-C-D-S-K-A-A-V-V-L-T-V-W-K-K-S-L-L-F-N-C-D-G-F-T-V-Y-N-A-N-G-E-L-V-F-R-V-D-N-Y-M-N-C-P-R-D-N-I-V-L-M-D-A-S-G-F-P-L-L-S-I-R-R-K-K-L-S-L-G-D-C-W-M-V-Y-D-G-E-T-E-R-D-P-I-F-T-A-R-K-N-V-S-I-I-S-N-R-K-S-L-A-W-V-S-A-K-K-T-V-L-Y-E-I-E-G-S-Y-G-Q-R-S-C-K-I-L-D-E-R-R-N-K-K-K-T-A-E-I-K-R-K-E-T-V-I-G-G-V-A-F-G-K-D-V-Y-K-L-I-V-E-S-E-M-E-P-R-V-A-M-A-L-T-I-I-L-D-Q-M-F-R-S-S"} +{"text": "### FUNCTION Putative antitoxin component of a possible type II toxin-antitoxin system May neutralize the effect of cognate toxin Rv3098A/RVBD_3098A ### SEQUENCE -M-T-A-T-I-G-F-R-P-T-E-K-D-E-Q-I-I-N-A-A-M-R-S-G-E-R-K-S-D-V-I-R-R-A-L-Q-L-L-E-R-E-V-W-I-K-Q-A-R-T-D-A-E-R-L-R-D-E-D-V-S-T-E-P-D-A-W"}