### FUNCTION A scaffold on which IscS assembles Fe-S clusters Subsequently gives the nascent cluster to other proteins It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters ### SEQUENCE -M-A-Y-S-K-K-V-I-D-H-Y-E-N-P-R-N-V-G-S-F-K-T-I-D-A-N-V-G-S-G-L-V-G-A-P-A-C-G-D-V-M-K-L-Q-I-K-V-N-K-N-G-I-I-Q-D-A-C-F-K-T-Y-G-C-G-S-A-I-A-S-S-S-L-V-T-E-W-I-K-G-K-S-L-I-E-A-E-N-I-K-N-T-N-I-A-E-E-L-D-L-P-P-V-K-I-H-C-S-I-L-A-E-D-A-I-K-A-A-I-T-D-Y-K-N-K-N-K


### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-M-N-Y-R-H-I-L-V-M-I-D-L-S-P-D-S-Y-S-L-I-H-K-A-S-F-I-S-N-L-H-N-D-A-K-I-S-L-I-Y-V-N-T-D-Y-S-D-A-Y-T-G-L-I-D-V-D-I-R-N-I-Q-S-Y-R-L-Q-D-I-N-N-M-L-K-N-L-K-N-Y-I-Y-F-P-V-H-K-V-F-I-G-N-G-D-M-T-S-C-L-L-D-V-T-Q-K-Y-N-I-D-L-I-I-F-G-H-Y-Q-D-F-W-S-K-I-V-F-S-L-R-Q-I-I-N-S-L-H-I-D-M-L-I-V-P-F-Y


### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-K-I-H-P-D-Y-F-K-I-N-V-T-C-S-C-G-N-N-I-N-I-F-S-T-L-S-K-N-I-N-V-D-V-C-S-K-C-H-P-F-Y-T-G-Q-Q-R-T-S-D-T-G-G-R-I-E-K-F-H-K-R-F-N-I-S-S-H


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-N-T-D-I-K-N-L-I-W-I-D-L-E-M-T-G-L-N-P-N-I-H-K-I-I-E-I-A-T-L-I-T-D-K-N-L-K-I-L-S-Y-G-P-V-I-A-I-Y-Q-N-N-H-Q-L-S-F-M-D-P-W-N-N-K-M-H-T-K-N-G-L-I-T-R-I-K-N-S-L-Y-T-E-H-L-A-E-I-K-T-I-T-F-L-K-K-W-V-P-K-N-T-S-P-M-C-G-N-S-I-S-T-D-R-Q-F-L-F-K-Y-M-P-T-L-E-K-Y-F-H-Y-R-Q-I-D-V-S-T-I-K-E-L-A-L-R-W-K-P-K-I-Y-N-K-L-K-K-K-T-L-I-K-H


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-I-L-L-I-H-P-D-C-S-E-K-L-P-I-M-I-E-K-F-K-K-L-V-I-G-Y-K-G-R-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-S-I-N-K-L-H-K-A-H-Y-F-L-M-N-I-E-V-P-S-N-C-I-Q-D-L-S-N-T-F-R-Y-D-D-L-V-I-R-N-I-I-M-H-V-K-K-S-V-T-E-I-S-P-M-L-K-S-K-E-D-K-L-D-K-K-D-R-V-V-V-S


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-E-K-L-D-N-L-G-N-K-G-D-I-L-F-V-K-S-G-Y-A-R-N-F-L-I-P-Y-G-K-A-I-F-A-T-K-D-N-I-K-F-E-I-N-K-K-E-E-L-E-R-E-L-I-K-K-I-S-I-A-K-T-K-C-E-K-I-K-N-I-K-S-I-V-I-P-A-Q-V-G-I-E-G-K-L-F-G-S-V-G-S-R-D-I-A-K-K-L-S-E-L-S-N-I-K-I-K-K-H-E-I-Y-F-L-N-G-A-L-K-H-V-G-Q-H-K-V-I-F-K-P-H-H-S-V-S-I-T-V-E-I-N-I-V-S-Q-D-K-D-K


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-I-I-I-A-L-D-F-G-T-K-N-I-G-V-A-V-G-Q-N-Y-T-N-T-A-R-S-L-P-S-I-K-V-K-N-K-K-L-N-I-E-K-L-N-K-L-I-D-E-W-K-P-N-A-I-V-V-G-H-P-L-N-I-D-G-T-K-Q-K-I-T-Q-C-S-E-N-F-S-K-K-L-K-N-I-F-K-I-P-I-L-L-H-D-E-R-L-S-T-V-E-A-K-A-I-L-F-E-K-Y-G-Y-K-S-L-K-K-E-R-I-D-S-M-S-A-V-I-I-L-E-S-W-F-L-Y-S-K-N


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-S-R-G-I-N-K-V-I-L-I-G-Y-L-G-Q-D-P-D-V-R-Y-M-Q-N-G-S-A-V-T-N-I-T-L-A-T-S-E-T-W-K-D-K-N-N-G-E-I-K-E-K-T-E-W-H-R-I-V-F-F-N-K-L-A-E-I-A-G-E-Y-L-K-K-G-S-Q-V-Y-I-E-G-S-L-Q-T-R-K-W-K-D-Q-N-G-I-E-R-Y-I-T-E-I-I-V-S-V-G-G-T-M-Q-M-L-G-S-R-N-S-S-S-L-T-A-S-S-G-L-S-K-N-N-D-N-L-S-K-Q-L-L-S-E-K-K-Q-E-S-F-N-D-S-K-L-Q-N-N-N-L-D-F-D-D-E-D-I-P-F


### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-V-S-V-S-Q-S-A-Q-N-Y-F-L-N-L-L-K-K-Q-K-Y-G-T-N-I-R-V-Y-V-K-Y-P-G-T-P-V-A-K-C-G-V-S-Y-C-Y-K-D-D-V-T-R-L-D-V-A-F-T-M-N-K-F-I-V-Y-V-Y-K-P-H-I-P-Y-L-R-E-S-K-I-D-I-N-V-E-E-C-N-S-Q-L-T-L-I-A-P-Y-A-N-K-C-Y-F-I-K-N-N-D-L-K-R-R-V-E-N-F-L-N-L-N-I-N-P-Q-L-S-A-H-G-G-K-V-D-L-M-N-I-T-E-S-G-Y-L-S-L-K-F-S-G-G-C-N-G-C-S-M-V-Q-K-T-L-K-E-G-I-E-K-Q-I-L-A-K-F-S-E-F-K-G-V-Y-D-I-T-Q-H-N-R-G-N-H-S-Y-Y


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine  at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-N-Y-T-V-L-V-I-G-P-P-Y-S-T-Q-N-S-T-S-A-F-L-F-S-R-A-V-I-L-N-H-H-K-L-L-S-I-F-F-Y-C-D-G-A-L-N-A-N-K-F-I-S-P-N-F-N-E-C-N-L-V-E-E-W-T-W-L-H-N-K-Y-L-V-K-L-C-V-C-V-S-A-A-L-R-R-G-V-I-D-V-V-S-N-T-K-Q-N-K-N-I-K-V-G-N-L-K-S-S-F-F-L-T-G-L-G-E-F-S-N-Y-L-K-I-S-D-R-V-I-Q-F


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine  at tRNA wobble positions ### SEQUENCE -M-K-K-I-A-F-V-F-S-Y-V-P-H-G-V-S-L-G-R-E-G-L-D-L-L-L-S-V-S-I-M-N-S-K-I-S-V-F-F-I-G-D-G-I-F-Q-L-L-K-N-Q-K-P-D-E-I-L-S-K-N-Y-V-L-S-F-K-I-L-P-F-F-G-I-Y-D-F-F-L-C-N-E-S-L-K-E-R-G-L-F-K-K-T-D-F-L-L-D-V-S-I-L-S-A-I-E-I-R-N-K-L-K-N-S-D-L-I-I-N-F


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine  at tRNA wobble positions ### SEQUENCE -M-L-H-I-L-M-R-S-P-F-E-T-N-M-V-L-L-M-N-M-L-E-S-V-D-D-I-L-M-L-Q-N-S-V-V-L-A-L-K-N-N-V-F-L-N-K-I-L-S-Y-S-V-S-M-Y-A-L-K-Q-D-L-C-A-R-G-I-L-D-N-I-S-P-N-V-N-V-I-G-Y-N-R-F-V-D-L-T-V-K-H-K-Q-Q-M-S-W


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-V-N-Q-L-V-R-K-S-R-S-R-K-L-I-K-N-N-V-P-A-L-N-K-C-P-Q-K-R-G-V-C-I-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-Y-E-V-T-A-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-I-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-V-I-R-G-A-L-D-C-S-G-V-K-S-R-S-Q-G-R-S-K-Y-G-V-K-K-K-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-G-I-G-H-R-K-I-L-S-D-P-K-F-S-S-E-M-V-A-K-L-I-N-I-I-M-V-D-G-K-K-S-I-A-E-E-I-V-Y-Q-A-L-T-M-L-A-K-K-I-G-K-P-E-L-E-V-L-E-L-A-L-E-N-V-R-P-T-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-I-E-V-R-P-V-R-R-H-A-L-A-M-R-W-I-V-H-S-A-R-K-R-I-D-K-S-M-I-I-R-L-S-N-E-L-S-D-A-I-E-N-K-G-S-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-Q-N-Q-R-I-R-I-R-L-K-A-F-D-H-R-L-I-D-Q-S-T-S-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-H-K-E-K-F-T-V-L-I-S-P-H-V-N-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-L-I-D-I-V-E-P-T-E-K-T-V-D-A-L-M-R-L-D-L-A-A-G-V-D-V-Q-I-S-L-G


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-Y-E-K-I-L-L-K-V-L-L-G-P-H-I-S-E-K-S-S-T-L-S-G-N-F-S-T-V-I-I-K-V-S-I-C-A-T-K-L-E-I-K-R-A-V-Q-N-M-F-N-V-A-V-K-N-V-N-T-L-V-V-Q-G-K-C-K-R-K-K-S-R-I-T-C-S-S-N-W-K-K-A-Y-V-T-L-K-R-G-Q-N-I-N-F-I-G-S-S-E


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-I-A-L-L-R-K-V-E-Q-A-V-E-I-R-D-K-K-P-I-R-T-W-S-R-R-S-T-I-F-P-K-M-V-G-L-T-M-L-I-H-N-G-R-Q-H-I-P-V-F-I-T-E-D-M-V-G-H-K-L-G-E-F-V-L-T-R-T-Y-R-G-H-T-A-D-K-K-V-K-K-R


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-N-T-K-F-R-K-M-H-K-G-K-N-R-G-L-A-I-G-T-N-V-H-F-G-L-Y-G-L-K-A-I-T-R-G-R-L-K-S-S-Q-I-E-S-A-R-R-A-I-T-R-A-I-K-R-Q-G-K-I-W-I-R-I-F-P-D-K-P-I-T-K-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-V-Q-P-G-K-I-L-Y-E-I-S-G-V-S-E-E-L-S-R-I-A-F-K-L-A-A-A-K-L-P-V-K-T-M-F-V-T-K-L-V-M


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-I-D-K-F-R-T-L-S-G-Q-V-I-S-N-K-M-Q-K-S-A-I-V-S-I-K-R-L-I-K-H-P-L-Y-K-K-F-V-K-K-T-T-K-L-C-I-H-D-E-N-N-Q-C-S-F-G-D-I-V-E-I-R-E-C-R-P-I-S-K-T-K-S-W-M-L-V-R-I-S-K-K-S-L-R-S


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-E-Q-S-I-L-N-V-A-D-N-S-G-A-R-L-A-M-C-I-K-V-L-G-G-S-R-R-R-Y-A-G-I-G-D-I-I-K-I-S-I-K-E-A-I-P-R-G-K-V-K-K-G-E-V-F-K-A-V-I-I-R-T-K-K-G-V-K-R-S-D-G-S-I-I-R-F-D-T-N-A-C-V-V-L-N-N-N-D-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-N-D-K-F-M-K-I-I-S-L-A-P-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-K-K-N-D-Q-V-I-V-L-I-G-K-D-K-G-K-I-G-I-V-R-K-V-I-A-K-S-K-V-I-V-E-G-V-N-I-V-K-K-H-T-K-P-S-P-S-Q-N-K-K-G-G-I-V-E-Q-E-S-S-I-N-I-S-N-I-A-I-L-N-P-T-T-K-K-S-D-R-I-G-F-R-V-K-N-G-K-K-V-R-F-F-K-S-N-N-T-I-C-N


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-V-A-L-Y-D-Y-Y-K-N-S-I-S-K-K-L-M-L-N-F-N-Y-S-S-V-M-Q-V-P-K-I-D-K-I-T-L-N-I-G-V-G-I-A-T-I-D-K-K-N-L-D-F-A-I-S-D-L-T-K-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-I-A-S-F-K-I-R-K-G-Y-P-I-G-C-K-V-T-L-R-G-N-R-K-W-D-F-F-E-R-L-I-F-I-V-I-P-R-I-R-D-F-R-G-F-S-N-K-S-F-D-G-K-G-N-Y-S-I-G-I-K-E-Q-I-I-F-P-E-I-D-F-D-K-I-D-R-I-R-G-I-N-I-T-I-T-T-T-A-L-S-D-R-E-G-Y-A-L-L-S-A-F-N-F-P-F-R-T


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-E-V-K-R-I-K-L-A-K-K-F-Y-S-R-R-E-H-L-K-S-I-I-S-D-L-S-V-L-E-Q-D-R-W-K-A-V-L-K-L-Q-T-F-P-R-D-S-S-P-I-R-Q-R-N-R-C-S-Q-T-G-R-P-H-A-F-L-R-K-F-G-L-S-R-I-K-V-R-E-A-A-M-R-G-E-I-P-G-L-K-K-S-S-W


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-A-K-Q-P-I-V-I-P-S-D-V-S-I-T-L-I-G-Q-M-V-I-V-K-G-S-K-G-E-L-K-R-L-I-H-D-S-V-L-V-K-S-V-K-S-C-L-V-F-S-S-R-I-N-S-S-V-K-G-W-A-Q-A-G-T-A-R-S-L-V-N-S-M-I-H-G-V-T-V-G-F-F-K-K-L-K-L-F-G-V-G-Y-R-I-S-I-N-S-S-K-N-L-N-M-S-L-G-Y-S-H-I-I-E-Y-V-L-P-F-G-I-F-V-E-S-I-S-Q-A-E-I-I-V-K-G-I-N-K-Q-L-V-G-Q-V-A-A-N-L-R-A-Y-R-K-S-E-P-Y-K-G-K-G-I-R-Y-S-N-E-I-V-R-V-K-E-A-K-K-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-I-S-I-N-K-K-K-A-R-L-R-R-A-A-R-T-R-F-Q-I-K-K-L-H-L-I-R-L-V-V-H-R-T-S-K-H-I-Y-A-Q-I-I-D-S-K-N-A-L-V-L-T-S-A-S-T-V-E-K-E-I-L-N-L-V-K-Y-T-G-N-I-H-A-S-I-C-I-G-K-K-I-A-E-R-A-L-M-K-G-I-I-N-V-S-F-D-R-S-G-F-Q-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-S-G-L-K-F


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-N-I-G-R-N-V-S-G-D-L-K-E-K-L-I-S-V-N-R-V-S-K-T-V-K-G-G-R-I-F-S-F-S-A-L-T-V-V-G-D-G-H-G-K-V-G-F-G-Y-G-K-A-R-E-V-P-S-A-I-Q-K-A-M-E-K-A-R-R-N-M-I-Q-V-P-L-N-N-G-T-L-Q-Y-S-V-T-G-S-Y-T-G-S-Y-I-F-M-K-P-A-S-N-G-T-G-I-I-A-G-G-A-M-R-S-V-L-E-V-A-G-V-H-N-V-L-A-K-T-Y-G-S-T-N-P-I-N-V-V-R-A-T-M-L-V-L-E-S-M-K-S-P-E-M-I-A-L-K-R-N-K-L-V-K-E-I-L-E-N-S-Y-L


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Y-L-N-T-L-S-P-N-S-K-S-H-K-K-S-K-R-V-G-R-G-I-G-S-G-F-G-K-T-S-G-R-G-H-K-G-Q-K-S-R-S-G-C-K-I-R-R-G-F-E-G-G-Q-M-P-L-Y-R-R-I-P-K-F-G-F-V-S-L-K-K-E-K-V-A-E-V-R-L-E-D-L-K-N-F-S-N-C-I-I-N-L-Q-F-L-K-K-T-G-L-I-K-K-N-I-K-Y-V-K-I-I-S-S-G-S-I-I-T-N-I-L-I-I-R-N-L-F-V-S-K-S-V-R-N-I-I-E-S-S-G-G-K-I-E-E-N-N


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-A-N-H-K-H-V-V-V-A-L-M-D-V-Y-G-I-G-K-T-R-S-K-L-I-C-L-R-T-N-I-S-E-S-I-K-I-L-D-L-T-K-D-Q-L-E-L-L-R-C-E-V-L-K-F-V-V-E-G-D-L-R-R-E-V-T-L-S-I-K-R-L-Q-D-L-N-C-Y-R-G-S-R-H-R-K-K-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-L-M-K-K


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-S-K-D-G-L-N-N-L-M-Q-H-A-Q-K-I-Q-E-Q-M-K-K-I-Q-Q-E-V-S-E-I-E-V-T-G-E-S-G-A-G-A-V-K-V-T-L-I-G-S-H-Y-C-K-K-I-E-L-D-K-N-T-I-L-E-H-D-K-E-I-L-E-D-L-I-T-A-A-F-N-D-A-V-R-K-I-S-D-L-Q-K-Q-K-M-S-S-I-S-S-E-M-K-F-S-N-N-L-N-L-P-F


### FUNCTION Cytochrome bo ### SEQUENCE -M-L-K-N-R-Y-L-K-Y-L-F-I-L-I-L-L-S-I-L-S-I-M-P-I-F-A-I-I-Y-R-I-F-S-R-N-Y-L-Y-A-F-I-I-V-C-L-F-F-Q-I-L-A-H-I-K-F-F-L-N-L-D-F-S-L-E-Q-R-W-K-L-I-S-V-I-F-S-L-V-V-G-L-I-I-L-L-G-S-I-W-V-I-K-N-L-N-N-N-L-C-I-M


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine ### SEQUENCE -M-N-Y-I-P-D-W-N-E-E-L-A-K-K-I-A-K-S-E-F-I-N-M-T-P-D-H-W-E-I-I-Y-I-I-R-N-F-Y-L-N-F-N-L-A-P-S-I-R-I-L-I-K-T-L-E-K-M-K-Y-N-K-K-K-C-S-S-R-Y-L-L-K-L-F-P-K-N-P-I-K-Q-A-S-K-I-A-G-V-P-K-T-N-D-C-I


### FUNCTION Sulfur carrier protein involved in sulfur trafficking in the cell Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine  in tRNA Interacts with IscS and stimulates its cysteine desulfurase activity Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin ### SEQUENCE -M-T-V-D-N-N-V-L-D-L-R-K-L-R-C-P-E-P-I-M-L-L-R-K-K-I-R-E-I-K-N-G-T-T-L-L-I-L-S-D-D-P-S-T-I-R-E-I-P-Q-Y-C-K-F-M-H-H-K-L-L-K-I-N-T-K-D-T-I-Y-K-F-W-I-Q-K-T-H-K-M


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-Y-I-Q-K-Y-E-K-K-Q-I-K-K-T-I-P-I-F-K-S-G-D-T-I-I-I-K-V-W-I-V-E-G-T-K-K-R-I-Q-L-F-E-G-I-V-I-A-I-R-N-R-G-F-N-S-S-F-C-V-R-K-V-S-N-G-E-G-I-E-R-V-F-P-K-Y-S-P-I-I-E-E-I-I-V-K-R-H-G-D-V-K-K-S-K-L-Y-Y-L-R-N-R-I-G-K-S-A-K-I-R-E-L-I-S-K-K-T-S


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-Y-I-K-S-F-S-A-K-S-N-D-F-K-K-M-W-Y-C-I-D-A-T-G-K-I-L-G-R-L-A-T-N-I-A-S-R-L-R-G-K-H-K-V-E-Y-T-P-H-V-D-I-G-D-Y-L-I-V-I-N-A-K-N-I-K-V-T-G-K-K-C-T-D-K-F-Y-Y-H-H-T-G-Y-V-G-G-L-K-K-I-A-F-K-D-M-L-H-R-Y-P-E-R-I-I-E-I-A-V-R-G-M-L-P-K-G-P-L-G-R-S-M-F-K-K-L-K-V-Y-A-N-D-N-H-N-H-S-A-Q-N-P-K-I-L-N-I


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-F-K-S-G-G-K-Q-H-K-V-I-K-G-Q-T-I-R-L-E-K-I-N-Q-S-I-G-T-Q-I-K-F-K-K-I-L-M-C-C-N-G-T-H-I-T-I-G-K-P-H-I-H-N-N-F-I-L-A-N-I-I-N-H-G-R-H-K-K-I-K-I-I-K-F-N-R-R-K-H-Y-K-K-Q-Q-G-H-R-Q-N-F-T-D-V-L-I-T-N-I-H-N-N-Y-R-E-Q-N-N-G-S


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-E-N-M-N-I-K-S-K-I-I-T-Q-F-G-V-N-S-K-D-S-G-K-S-E-V-Q-I-A-L-L-T-N-R-I-N-Y-L-Q-N-H-F-S-L-H-K-K-D-H-C-S-R-R-G-L-L-N-M-V-S-K-R-R-K-L-L-N-Y-L-K-D-E-N-I-S-R-Y-I-N-I-I-N-Q-L-K-L-R-R


### FUNCTION Structural component of flagellum, the bacterial motility apparatus Part of the rod structure of flagellar basal body ### SEQUENCE -M-L-D-K-I-N-N-D-F-N-I-N-K-I-L-L-N-L-H-A-Y-R-Q-E-I-L-A-S-N-I-A-N-A-N-T-P-G-H-K-S-S-D-I-N-F-S-K-T-F-G-K-L-F-S-N-A-L-Q-G-K-K-N-N-L-T-T-T-S-N-K-H-I-S-N-N-D-N-V-E-L-S-N-Y-D-E-Q-T-V-K-N-N-S-Y-V-S-K-N-N-A-I-N-I-D-V-D-R-I-N-F-V-H-N-G-L-K-Y-N-A-D-V-V-F-I-N-N-K-F-K-N-I-M-N-V-L-K-G


### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-A-L-L-D-F-F-L-S-R-K-K-N-T-A-N-I-A-K-E-R-L-Q-I-I-V-A-E-R-R-R-M-D-T-E-P-Q-Y-L-P-K-L-K-K-E-I-F-Q-V-I-C-K-Y-I-K-I-N-P-E-K-I-K-I-Q-L-D-Q-T-N-K-N-I-S-I-L-E-L-N-V-T-L-S-E


### FUNCTION Low-potential electron donor to a number of redox enzymes ### SEQUENCE -M-E-S-I-G-I-F-F-G-S-D-T-G-N-T-E-N-V-A-K-L-I-H-K-Y-I-G-T-N-I-S-S-I-H-D-I-A-N-T-N-K-K-D-I-E-L-F-N-I-L-I-F-G-V-S-T-W-Y-Y-G-E-L-Q-C-D-W-D-D-F-L-P-T-L-K-K-I-N-F-N-N-K-I-I-A-L-F-G-C-G-D-Q-E-D-Y-S-E-Y-F-C-D-G-I-G-I-L-Y-N-V-I-R-L-S-K-N-V-R-F-I-G-S-W-T-S-K-G-Y-S-F-E-C-S-K-A-L-D-K-N-K-N-F-L-G-L-V-I-D-E-D-R-Q-P-E-Q-S-N-Q-R-I-I-Q-W-T-K-K-I-K-T-E-L-N-S-L-L-N


### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-F-L-L-N-S-I-P-T-I-S-F-F-I-F-Y-K-F-Y-D-I-F-I-A-S-F-S-L-M-I-A-S-L-F-T-F-I-I-T-S-I-L-F-N-S-I-N-K-H-D-L-I-N-L-I-F-V-I-V-F-G-F-L-T-L-F-Y-H-N-S-S-Y-I-K-W-K-V-T-I-I-Y-F-L-I-S-I-V-F-L-I-N-Y-L-F-I-K-N-N-L-L-N-I-I-F-K-N-T-I-Q-L-S-K-N-V-W-R-K-L-S-L-F-W-S-I-F-F-L-I-C-A-V-S-N-T-Y-I-I-L-Y-F-S-E-Q-T-W-V-T-F-K-I-F-G-L-T-I-L-T-L-I-A-V-I-I-N-G-F-Y-I-Y-F-L-K-S-K-I-I-Q


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-R-N-S-N-R-K-P-N-E-I-C-I-N-R-K-A-K-Y-S-F-S-I-K-E-T-F-E-A-G-I-V-L-L-G-W-E-V-K-S-V-R-C-G-K-I-N-I-S-N-S-Y-I-S-L-K-N-G-E-M-Y-L-V-N-S-Q-F-D-P-I-S-K-S-N-L-Y-I-T-Y-E-C-N-R-I-K-K-I-L-L-R-K-R-E-I-T-Y-L-Y-S-K-L-Y-K-S-H-L-T-I-I-V-L-S-I-F-F-K-K-Q-W-C-K-V-K-I-G-I-A-K-G-K-T-I-K-D-K-R-E-H-K-K-L-S-E-W-K-K-T-Q-N-R-F-V-K-R-I-R-H


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-I-D-N-D-L-L-S-K-N-K-E-A-K-V-V-S-E-N-S-T-V-E-I-N-D-V-T-N-S-D-S-K-N-T-D-N-D-F-Q-T-E-E-L-N-N-F-E-K-I-F-L-N-L-N-S-D-L-L-N-Q-Q-L-L-V-K-N-N-L-K-L-Y-K-I-R-A-E-K-E-I-N-R-A-Y-K-F-S-L-K-S-F-I-S-S-L-F-P-V-I-D-S-M-E-Y-A-L-N-L-F-K-K-D-D-K-I-L-C-L-I-F-N-E-L-D-N-V-S-Q-S-L-M-N-L-L-V-K-F-G-V-T-S-I-K-D-I-N-I-A-F-N-P-D-I-H-Q-A-I-T-T-Q-V-S-K-D-I-K-N-N-Y-V-I-S-I-M-Q-K-G-Y-L-L-Y-D-R-L-L-R-P-A-M-V-I-V-S-K-N-D-I


### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-Y-N-S-N-I-T-D-I-T-T-L-L-P-H-R-Y-P-F-L-L-I-D-R-I-I-A-Y-Q-K-N-F-N-I-L-T-I-K-N-I-S-Y-S-E-F-C-F-T-G-H-F-Y-K-N-P-V-F-P-G-V-L-I-L-E-A-I-A-Q-S-A-C-L-L-V-Y-K-S-F-G-M-S-Y-K-N-N-L-F-Y-L-T-N-I-I-D-V-K-F-K-K-K-V-I-P-G-D-Q-M-L-I-N-V-F-V-D-K-H-H-H-R-L-I-R-F-V-G-H-V-S-V-S-K-Y-I-V-C-K-A-T-I-S-C-L-L-T-N-D-V-V-S-R


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-E-R-I-K-N-F-T-S-S-K-M-D-H-C-V-H-M-F-V-N-Q-L-N-T-L-R-S-S-R-A-S-P-S-I-L-D-T-I-L-I-D-Y-L-G-Q-K-I-Q-L-K-K-L-S-N-I-I-V-E-N-V-N-T-L-R-I-T-L-F-D-P-K-I-K-N-N-V-E-K-A-I-I-S-S-K-L-D-L-I-P-I-F-I-N-N-Y-F-Q-I-K-I-P-V-L-T-E-E-R-R-L-Q-L-I-K-L-A-K-K-M-A-E-N-S-R-I-C-I-R-N-I-R-R-L-S-N-E-K-I-K-L-F-L-K-D-K-I-I-S-S-D-K-E-R-R-L-Q-H-E-V-Q-D-I-T-N-S-Y-M-E-K-I-N-V-I-L-S-K-K-E-K-D-L-L-K


### FUNCTION Essential cell division protein ### SEQUENCE -M-N-K-N-Y-N-L-S-K-I-I-F-N-D-L-I-S-F-Y-K-T-Q-L-I-L-I-F-M-I-F-I-S-A-L-L-I-I-T-I-I-H-K-T-R-L-L-T-S-Q-Q-E-E-L-D-I-I-K-K-K-Q-M-P-L-N-L-E-K-Y-I-S-T-S-R-L-K-F-K-H-E-K-I-D-T


### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-K-N-N-I-S-K-F-P-L-S-F-S-K-S-A-I-K-K-I-K-T-I-I-S-E-K-N-I-P-N-L-K-F-R-V-Y-I-A-G-G-G-C-S-G-F-Q-Y-K-F-K-F-D-K-N-K-N-K-N-D-T-I-V-N-I-F-N-N-I-I-I-I-D-P-I-S-L-Q-Y-L-R-G-G-Q-I-D-Y-I-E-N-L-E-G-S-K-F-I-I-L-N-P-K-A-K-H-T-C-G-C-G-S-S-F-S-I


### FUNCTION Transcription factor that acts by binding directly to the RNA polymerase  Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters ### SEQUENCE -M-Q-K-E-K-N-K-K-Q-S-S-L-S-I-L-F-M-A-G-V-Q-P-Y-K-N-K-K-N-E-K-Y-M-N-T-K-Q-I-D-H-F-K-K-I-L-I-A-W-K-N-Q-L-R-N-D-I-S-Q-T-R-L-N-I-Q-D-K-A-T-N-Y-P-D-P-I-D-R-A-V-Q-E-E-E-F-S-F-E-L-R-H-R-D-R-E-R-K-L-I-E-K-I-E-K-T-L-K-K-V-E-N-K-D-F-G-Y-C-E-S-C-G-I-E-I-G-I-K-R-L-E-A-R-P-T-A-N-L-C-I-D-C-K-T-L-S-E-I-R-E-K-Q-I-L-G


### FUNCTION Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters ### SEQUENCE -M-N-D-I-I-K-K-I-Q-N-Q-I-Q-N-N-P-I-I-I-Y-M-K-G-S-P-D-A-P-S-C-G-F-S-A-Q-A-V-H-A-I-S-S-C-G-K-K-F-A-Y-I-D-V-L-K-N-P-D-I-R-L-E-L-P-K-Y-A-N-W-P-T-F-P-Q-L-W-V-N-G-E-L-I-G-G-C-N-I-I-L-E-L-F-Q-K-G-E-L-K-K-T-I-S-I-C-D-K-L-N-S


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-D-I-D-K-H-K-K-E-T-Q-T-E-S-K-N-D-L-N-N-T-T-I-T-Q-N-N-V-S-D-D-C-Q-N-Q-D-K-I-N-S-L-K-Q-K-I-L-E-I-K-K-H-I-S-E-V-K-L-R-E-Q-A-E-I-E-N-I-N-K-N-T-K-N-K-I-K-I-I-I-D-T-Q-L-E-N-F-F-R-N-L-I-P-I-I-D-S-L-K-N-I-R-K-D-I-N-K-Y-N-N-I-K-D-N-N-M-I-Q-G-I-P-L-I-L-K-S-L-L-T-V-T-E-K-F-G-L-K-I-N-N-K-K-G-K-L-F-D-P-K-L-H-T-T-I-P-N-E-N-C-K-N-I-N-E-Y-Y-V-S-E-I-I-Q-D-G-Y-T-F-H-E-K-I-I-R-K-A-I-V-K-L-S-K-D-K-K-T


### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur ### SEQUENCE -M-E-F-F-F-Y-S-S-S-L-A-T-I-V-F-T-V-C-S-I-F-S-R-N-L-M-Y-S-L-L-Y-L-I-L-S-F-V-F-T-S-C-V-F-F-S-L-G-A-T-F-A-A-A-L-E-V-I-I-Y-A-G-A-I-M-V-L-F-V-F-F-I-M-M-F-N-F-K-K-S-T-L-Y-A-E-K-I-F-D-K-N-N-Y-Y-Y-I-N-F-L-F-L-L-C-I-L-I-F-P-F-F-F-I-L-S-Y-L-Y-K-E-K-I-F-Y-M-V-V-S-T-K-L-V-A-I-K-L-F-S-D-Y-I-L-V-I-E-L-S-S-I-V-L-L-S-A-L-I-I-V-S-H-I-G-K-I-R-R


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-S-K-K-D-S-I-K-S-R-K-K-K-K-L-N-A-S-K-K-S-M-I-K-T-L-I-K-K-V-K-I-A-I-L-S-G-D-K-L-K-S-E-L-A-F-S-K-I-Q-P-I-L-D-R-Y-S-A-K-G-L-I-H-K-N-K-A-A-R-H-K-S-N-L-K-C-K-I-N-A-L


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-L-T-I-Y-G-I-S-R-T-K-C-G-K-K-A-S-R-R-L-R-L-Q-N-K-F-P-A-I-I-H-V-S-L-I-S-N-I-S-I-E-L-S-Q-N-D-F-I-N-I-E-M-K-N-S-D-F-Y-K-S-E-V-I-L-I-V-D-K-V-K-Y-I-V-K-I-Q-E-I-Q-R-H-A-F-K-S-K-I-L-H-I-D-F-L-K-V-S-V


### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon  protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-D-N-F-I-S-H-I-Y-A-V-E-N-S-T-T-I-P-S-S-N-S-Y-S-L-I-F-M-L-L-V-F-L-S-I-F-Y-F-M-I-F-R-P-Q-R-K-K-I-Q-E-H-D-R-L-I-K-S-L-S-Y-G-D-E-V-F-T-S-S-G-F-V-G-K-I-V-K-I-T-K-T-G-Y-I-V-L-E-L-N-N-N-V-E-V-F-V-K-S-D-F-I-V-S-I-F-P-K-G-T-L-K-N-M-K-S-M


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-H-V-K-R-G-V-I-A-R-A-R-H-K-K-V-L-K-Q-A-K-G-Y-Y-G-A-R-S-R-T-Y-R-T-A-R-Q-A-I-I-K-A-G-Q-Y-S-Y-R-D-R-R-Q-R-K-R-Y-F-R-K-L-W-I-T-R-I-N-A-A-V-R-E-N-Q-I-S-Y-S-K-F-M-Y-G-L-K-K-A-S-I-A-V-D-R-K-M-L-S-E-L-A-I-F-D-N-V-S-F-C-S-L-I-K-S-S-K-D-A-L-T-S-I-E-L-N-K-N-L


### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-V-M-H-F-F-L-L-F-V-S-N-I-L-I-N-N-F-I-L-V-R-F-L-G-L-C-P-F-M-G-I-S-R-T-I-D-S-A-I-G-M-G-L-A-T-T-C-V-I-V-F-V-S-I-I-S-W-L-I-N-F-Y-I-L-I-P-F-H-L-I-H-L-C-T-M-T-Y-M-L-I-I-A-V-S-V-Q-I-F-E-I-I-V-K-K-V-S-S-T-L-Y-R-L-L-G-I-Y-L-P-L-I-T-T-N-C-S-V-L-A-I-P-L-M-N-T-K-L-N-S-N-F-I-E-S-V-L-Y-G-F-S-S-S-L-G-F-F-L-V-L-V-I-F-S-S-I-R-E-R-I-S-E-S-D-V-P-M-Y-F-R-G-Y-P-I-A-L-I-T-A-S-L-L-A-I-A-F-M-G-F-D-G-L-I-K-F


### FUNCTION Role in flagellar biosynthesis ### SEQUENCE -M-T-I-E-S-V-M-S-L-F-Y-D-A-M-K-V-T-L-M-I-S-L-P-L-L-L-S-A-L-C-C-G-L-I-V-S-I-F-Q-A-A-T-Q-I-N-E-Q-T-L-S-F-I-P-K-I-A-A-V-L-V-S-I-V-I-F-G-P-W-M-L-V-I-L-S-D-Y-T-H-T-L-F-Y-N-L-S-Y-I-T-Y-S


### FUNCTION FliN is one of three proteins ### SEQUENCE -M-D-N-I-L-V-N-N-K-N-K-N-L-L-D-L-N-K-E-D-I-K-K-S-C-E-I-E-D-K-I-F-H-S-K-T-V-N-D-V-D-L-N-L-N-S-K-N-D-I-S-S-K-M-K-F-I-M-D-V-P-V-H-L-T-I-E-V-G-T-V-K-I-T-I-K-D-L-L-E-L-R-S-K-S-I-L-V-L-D-K-H-A-G-D-P-L-N-I-L-V-N-G-Y-V-I-A-T-G-E-L-V-V-T-E-N-K-Y-G-I-R-I-I-N-I-I-D-N-S-V-F-K-K-L


### FUNCTION Flagellar protein that affects chemotactic events ### SEQUENCE -M-Y-K-K-K-R-C-F-T-L-L-K-Y-L-D-V-K-S-N-Y-H-I-V-L-N-L-K-K-I-L-S-G-I-I-Q-V-K-A-Q-L-D-I-L-M-S-Y-Q-C-E-Y-L-K-C-L-D-Q-E-L-K-F-Y-I-S-G-T-R-L-A-H-Y-Y-N-F-I-A-F-L-I-D-G-V-N-K-Q-N-D-T-M-C-K-L-Y-K-Q-Y-N-E-Y-I-Y-L-W-K-K-K-Q-K-K-I-K-M-W-N-N-I-N-S-R-L-L-L-N-R-F-K-L-S-Q-L-D-D-Q-D-L-L-D-S-C-C-T-Y-K-Y-L-L-K-N-D-R-E-D-T-D-Y-V


### FUNCTION General  is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-F-Q-R-D-I-K-I-T-T-P-N-G-L-H-T-R-P-A-A-L-L-V-K-E-A-K-K-F-I-S-E-I-N-I-I-S-N-G-K-S-A-N-A-K-S-L-F-K-L-Q-T-L-G-L-V-Q-N-S-L-I-T-I-S-A-H-G-I-D-E-K-V-A-V-E-D-L-A-K-F-L-T-T-L-K


### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-I-K-A-T-K-L-K-K-K-Y-D-K-L-K-I-A-K-W-S-F-L-G-I-L-I-I-L-F-I-L-S-N-H-Y-Y-I-K-H-S-N-I-F-Q-N-I-L-L-T-S-L-T-I-L-S-T-G-L-I-F-L-T-K-S-G-K-K-F-L-I-F-T-K-S-A-I-H-E-T-K-L-I-T-W-P-N-F-K-D-T-L-H-V-T-F-T-V-I-I-V-T-I-L-L-A-L-I-L-W-G-L-D-N-I-L-I-W-F-I-S-L-I-T-S-L-R-L


### FUNCTION Participates in transcription elongation, termination and antitermination In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase , probably by partially suppressing pausing In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho May be required to overcome a kinetic limitation of Rho to function at certain terminators Also involved in ribosomal RNA transcriptional antitermination ### SEQUENCE -M-Y-K-S-Y-K-K-R-W-Y-V-L-Q-A-F-S-G-F-E-G-R-I-A-Q-S-I-R-E-H-V-K-L-K-K-M-E-K-L-F-G-E-V-M-V-P-S-E-E-V-I-E-I-K-A-G-Q-R-K-K-S-E-Y-K-F-F-P-G-Y-V-L-I-Q-M-I-M-N-E-S-S-W-H-L-V-R-S-I-P-R-V-L-G-F-I-G-G-T-P-D-R-P-L-P-I-T-D-Q-E-V-N-T-I-I-N-K-L-K-Q-V-G-D-K-P-R-P-K-T-L-F-E-P-G-E-T-V-R-V-N-D-G-P-F-S-D-F-N-G-I-V-E-E-V-D-Y-E-K-N-R-L-K-V-S-V-S-I-F-G-R-S-T-P-V-E-L-D-F-S-Q-V-K-K-N


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-T-I-Q-A-Y-I-K-L-Q-V-S-A-G-T-A-N-P-S-P-P-I-G-P-A-L-G-Q-K-G-I-N-I-M-E-F-C-K-A-F-N-T-R-T-N-N-L-E-K-G-L-P-I-P-T-I-I-T-V-Y-S-D-K-S-F-S-F-I-T-K-T-P-P-A-S-V-L-L-K-K-A-A-G-I-T-K-G-S-S-K-P-N-Q-N-K-V-G-T-I-T-M-Q-Q-I-L-D-I-A-Q-I-K-K-I-D-M-T-G-S-N-I-D-N-I-S-K-S-I-I-G-T-A-N-S-I-G-L-I-I-A-E-G-T-N-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-M-L-D-F-K-K-K-K-E-L-V-T-Q-I-N-L-I-A-K-T-A-L-S-I-V-V-A-N-P-Q-G-I-K-S-N-D-I-T-Q-L-R-K-L-A-R-K-S-N-V-K-L-G-V-Y-R-N-T-L-L-N-L-G-I-K-N-T-P-F-E-C-L-K-N-I-L-I-G-P-T-L-I-A-Y-S-S-E-H-P-G-S-A-A-K-L-L-K-N-F-S-M-S-Q-S-S-N-P-N-F-K-I-L-G-A-V-F-E-G-K-A-I-S-G-S-N-I-N-S-L-A-D-I-P-T-F-N-E-A-L-R-R-F-I-I-I-A-K-E-I-S-A-G-K-L-L-R-I-L-V-S-I-K-N-I-K-E-N-S


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-I-T-K-E-Q-I-L-D-A-I-S-E-M-S-V-M-N-I-V-E-L-I-S-D-M-E-K-K-F-G-V-S-S-I-I-P-S-S-S-T-S-T-Q-N-I-E-T-A-E-A-K-T-E-F-D-V-L-L-K-S-I-G-G-N-K-V-S-V-I-K-A-V-R-S-A-T-G-L-G-L-K-E-A-K-D-L-V-E-S-A-P-T-I-I-K-E-R-I-T-Q-D-A-A-E-S-L-K-K-I-L-N-E-T-G-A-E-V-E-I-K


### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-S-E-L-I-N-I-I-S-K-K-S-N-L-S-K-I-Q-I-K-N-I-L-E-I-T-L-T-A-I-I-Q-S-L-K-D-G-N-S-V-Q-L-V-G-F-G-T-F-K-V-N-N-R-A-A-R-I-G-R-N-P-Q-T-G-Q-T-I-H-I-S-A-T-K-T-P-V-F-I-S-G-K-T-F-K-T-A-I-K-T-I


### FUNCTION Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle ### SEQUENCE -M-K-I-L-K-K-K-S-K-I-T-S-I-Q-I-I-S-G-K-Y-K-N-S-R-I-P-I-I-N-T-K-N-L-R-P-T-T-N-Y-I-R-E-T-L-F-N-W-I-S-N-E-K-I-K-K-S-H-C-L-D-C-F-S-G-S-G-A-L-G-I-E-A-V-S-R-Y-A-L-S-S-T-C-I-E-I-Q-K-K-A-I-F-F-L-K-K-I-L-I-K-L-S-I-T-N-V-H-V-I-R-A-N-T-I-Q-W-L-K-K-P-N-K-S-Y-D-I-I-F-L-D-P-P-F-K-T-T-L-L-K-Q-T-I-A-L-L-I-K-N-N-W-L-K-N-N-A-L-I-Y-I-E-Q-E-N-T-L-N-K-L-I-T-P-P-N-N-W-I-L-K-K-E-K-K-T-K-K-I-H-Y-S-L-Y-M-N-V-N-N-F


### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-E-L-C-H-S-N-Q-L-K-I-G-L-K-I-I-Y-N-N-E-P-C-I-V-V-S-N-E-F-I-K-P-G-K-G-Q-A-F-F-R-V-R-L-K-N-L-L-N-K-K-L-I-D-K-T-C-K-Y-S-D-C-F-K-I-A-N-V-I-E-I-T-A-T-Y-M-F-T-D-K-K-V-W-T-F-M-D-K-K-S-F-E-Q-I-F-V-E-K-N-I-I-K-N-V-L-P-W-L-L-E-Q-H-D-Y-I-I-S-L-W-N-D-Q-P-I-S-I-V-Y-S-S-N-F-I-E-L-I-V-V-N-T-I-P-N-A-R-S-G-A-I-N-T-Y-S-K-L-A-L-L-N-T-G-V-T-I-K-V-P-I-F-I-Q-I-G-Q-I-I-K-V-D-T-R-T-S-E-Y-I-S-K-I-S


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-N-N-N-K-V-Y-S-L-N-V-V-S-F-E-K-I-I-F-N-D-F-V-K-K-I-Q-V-S-G-S-E-G-E-L-G-I-Y-P-G-H-L-Q-L-L-S-L-I-K-P-G-P-L-L-I-L-D-D-H-D-Y-Q-H-V-I-Y-I-S-G-G-I-I-E-V-Q-P-T-V-V-S-I-L-A-D-T-A-I-R-G-L-D-L-D-L-N-V-V-L-D-K-K-L-K-L-E-N-K-I-S-N-V-D-C-I-D-R-N-D-V-I-Q-Q-L-S-C-E-L-A-K-L-R-V-I-E-M-F-K-N-Q-Y-I-K-K-N-N


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-S-T-K-D-E-L-Q-L-Y-A-K-A-I-Y-N-C-A-I-S-N-H-Q-S-L-D-H-W-K-T-M-L-Q-L-M-A-N-I-L-N-N-E-I-I-K-N-L-I-S-K-A-Y-F-S-Q-H-V-I-S-L-F-I-D-L-C-C-N-K-V-N-Q-Y-G-I-N-L-I-K-I-L-A-E-N-K-R-L-M-L-L-E-K-L-Y-K-E-F-I-N-L-C-E-L-Y-Q-G-V-V-N-I-T-V-I-S-A-H-K-L-N-E-E-Y-I-S-K-I-N-I-M-L-K-K-R-F-F-K-K-I-N-V-T-Y-V-I-D-E-S-I-I-G-G-L-I-I-K-F-C-D-T-V-I-N-A-S-I-H-S-R-L-E-K-L-L-N-I-L-Q-Y


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-F-N-V-T-I-V-G-Q-A-I-S-F-V-L-F-V-F-F-C-M-K-Y-V-W-P-S-V-I-F-I-I-E-T-R-Q-K-E-I-K-D-S-L-T-F-I-E-N-S-K-K-E-L-N-I-F-K-E-N-S-K-N-E-I-K-I-I-K-K-N-A-S-K-I-I-D-S-A-I-Q-Q-K-T-Q-I-L-K-Q-A-Y-L-A-A-E-K-E-K-Q-T-I-L-K-Q-A-K-L-D-V-M-I-E-Y-Q-K-A-R-Y-E-L-R-Q-K-V-S-K-I-A-V-E-I-A-K-K-I-I-N-R-S-I-C-I-E-E-Q-N-S-I-I-S-S-L-I-K-K-I


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-D-F-L-G-M-M-K-Q-A-A-Q-L-Q-S-K-M-Q-E-M-Q-D-A-L-G-N-V-E-V-E-G-I-S-G-G-G-L-V-V-V-R-M-T-A-K-M-D-V-K-G-V-K-I-D-P-S-L-M-K-A-E-E-R-E-V-L-E-D-L-L-V-T-A-L-G-D-A-R-R-K-A-E-A-A-V-Q-E-K-M-Q-S-L-T-G-G-L-G-L-P-P-G-L-F-G-Q


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-G-A-V-A-G-P-E-I-E-R-L-V-Q-L-L-A-R-L-P-G-L-G-P-R-S-A-R-R-A-A-L-H-L-I-K-K-R-E-A-L-M-M-P-L-S-S-A-L-Q-V-A-L-D-K-V-Q-V-C-K-T-C-G-N-I-D-T-Q-N-P-C-T-V-C-T-D-P-K-R-D-P-A-I-I-V-V-V-A-D-V-A-D-L-W-A-L-E-R-A-N-A-T-Q-G-R-Y-H-V-L-G-A-T-L-S-P-L-D-G-V-G-P-Q-D-L-T-I-D-A-L-V-A-R-A-H-A-A-E-V-H-E-V-I-L-A-L-N-A-T-V-D-G-Q-T-T-A-H-Y-I-T-D-L-L-Q-D-A-N-V-K-V-T-R-L-A-H-G-V-P-V-G-G-E-L-D-Y-L-D-E-G-T-L-S-A-A-M-R-Q-R-T-L-F


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-E-K-V-P-M-T-S-A-G-F-A-A-L-G-E-E-L-K-K-R-Q-S-E-D-R-P-R-I-I-E-H-I-A-E-A-R-S-H-G-D-L-S-E-N-A-E-Y-H-A-A-K-E-E-Q-S-H-N-E-G-R-I-A-E-L-E-D-K-L-A-R-A-D-I-I-D-I-S-K-L-S-G-D-T-I-K-F-G-A-T-V-T-L-V-D-E-D-T-E-K-K-A-V-W-Q-I-V-G-E-V-E-A-D-A-K-K-G-R-I-S-I-T-S-P-L-A-R-A-L-I-G-K-K-K-G-S-T-V-E-V-N-A-P-G-G-A-K-A-Y-E-I-T-K-V-E-W-R


### FUNCTION Has a post-transcriptional repressor function in flagellum biogenesis Associates with the 5'-UTR of fljK mRNA and promotes its degradation ### SEQUENCE -M-K-I-S-L-R-A-G-E-R-I-Y-I-N-G-A-V-L-R-V-D-R-K-V-S-V-E-L-V-N-D-V-M-F-L-L-E-G-Q-I-M-Q-A-S-D-A-T-T-A-M-R-Q-L-Y-F-I-V-Q-L-M-L-M-N-P-T-D-V-R-D-A-S-A-L-Y-G-Q-H-H-A-A-L-V-A-V-C-E-S-R-E-M-L-D-G-L-V-A-I-D-E-L-V-G-A-T-R-Y-F-E-A-L-K-R-I-R-A-L-F-P-V-E-Q-A-I-L-A-G-V-A-T-D-I-P-F-E-A-A


### FUNCTION Required for coenzyme pyrroloquinoline quinone ### SEQUENCE -M-A-W-K-A-P-K-I-V-E-V-P-C-G-M-E-I-N-M-Y-V-S-A-T-R-K


### FUNCTION Mediates sucrose transmembrane transport down a concentration gradient ### SEQUENCE -M-D-P-F-L-I-K-L-I-G-F-A-A-A-T-C-T-T-V-A-Y-A-P-Q-F-I-K-V-L-K-T-R-S-A-R-D-I-S-L-G-M-F-L-V-M-V-L-G-L-A-L-W-L-I-Y-G-L-L-S-G-D-A-P-L-I-A-S-N-A-V-T-M-L-L-A-G-G-I-L-V-M-K-L-R-Y-G


### FUNCTION Aminoacyl carrier protein Can be charged with L-glycine via the formation of a thioester bond between the amino acid and the 4'-phosphopantetheinyl prosthetic group, catalyzed by the bll6282 ligase ### SEQUENCE -M-H-N-T-A-I-N-V-Q-N-R-V-L-S-V-V-R-S-V-L-Q-Q-N-A-I-S-A-D-V-H-P-E-S-R-L-V-D-I-G-L-S-S-M-G-M-V-E-L-M-L-K-V-E-A-E-F-D-L-I-L-P-Q-F-E-I-T-P-E-N-F-R-S-V-K-A-M-E-R-M-I-L-N-Q-L-G-S-G-S-G


### FUNCTION Has a post-transcriptional repressor function in flagellum biogenesis Associates with the 5'-UTR of fljK mRNA and promotes its degradation ### SEQUENCE -M-A-L-K-V-E-L-K-P-H-E-R-I-I-V-G-N-S-V-I-T-N-T-D-Q-R-A-R-L-L-I-D-G-E-N-V-P-I-L-R-E-R-D-I-L-T-P-E-T-A-N-T-P-A-K-L-V-Y-L-A-V-Q-L-M-Y-I-S-P-D-P-Q-T-Q-H-G-T-Y-F-N-L-V-R-D-I-V-T-A-V-P-S-S-W-P-I-I-E-A-I-N-N-N-I-L-N-G-D-L-Y-R-A-L-K-D-A-R-K-L-I-A-Y-E-E-K-L-R-G-Q-Y-E-A-T-H-P-K-A-E-A-D-K-D-D-V-S-T-A-A


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-T-T-T-L-Y-T-S-D-H-E-W-L-A-I-E-G-D-V-A-T-V-G-I-T-D-Y-A-Q-S-Q-L-G-D-V-V-F-I-E-L-P-K-L-G-R-A-L-K-K-A-E-A-A-A-V-V-E-S-V-K-A-A-S-D-V-Y-A-P-V-T-G-E-V-L-E-T-N-D-A-L-A-A-E-P-A-L-V-N-S-D-A-Q-G-K-A-W-F-F-K-I-K-I-A-D-K-S-E-L-G-G-L-M-D-E-A-A-Y-K-A-H-T-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-T-G-Y-L-K-L-Q-V-P-A-G-A-A-N-P-S-P-P-I-G-P-A-L-G-Q-R-G-L-N-I-M-E-F-C-K-A-F-N-A-Q-T-Q-K-E-E-K-N-T-P-I-P-V-I-I-T-I-Y-A-D-R-S-F-T-F-E-M-K-T-P-P-M-S-Y-F-L-K-Q-A-A-K-I-Q-S-G-S-K-A-P-G-R-D-K-A-G-K-V-T-K-A-Q-V-R-E-I-A-E-K-K-M-K-D-L-N-C-D-T-I-E-S-A-M-K-M-V-E-G-S-A-R-S-M-G-L-E-V-A-G


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-T-A-N-R-K-E-L-A-V-E-R-A-A-K-K-E-A-V-E-Q-L-N-G-V-F-K-T-T-S-V-A-V-V-A-Q-Y-S-G-L-T-V-A-Q-M-Q-K-L-R-Q-Q-M-K-Q-A-G-A-S-V-K-V-S-K-N-R-L-A-K-I-A-L-E-G-T-D-V-V-A-I-G-P-M-L-K-G-P-T-V-I-A-T-S-N-D-P-V-A-A-P-K-V-A-I-E-F-A-K-A-N-E-K-F-V-I-V-G-G-S-M-G-K-T-V-L-N-V-D-G-V-K-A-L-A-S-L-P-S-L-D-E-L-R-G-K-I-V-G-L-I-V-A-P-A-T-K-L-A-Q-L-A-N-A-P-A-G-K-L-A-R-V-I-Q-A-H-A-S-K-G-E-A-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-D-L-Q-K-I-V-D-D-L-S-S-L-T-V-L-E-A-A-E-L-A-K-L-L-E-E-K-W-G-V-S-A-A-A-A-V-A-V-A-G-P-A-G-G-G-A-A-A-A-P-A-E-E-K-T-E-F-T-V-V-L-A-S-A-G-E-K-K-I-E-V-I-K-E-V-R-A-I-T-G-L-G-L-K-E-A-K-D-L-V-E-G-A-P-K-P-V-K-E-G-V-N-K-D-E-A-E-K-I-K-V-Q-L-E-K-A-G-A-K-V-E-L-K


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-I-A-Q-P-R-E-V-Q-K-S-R-K-K-V-P-A-L-Q-Q-S-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-V-R-L-T-N-G-F-E-V-I-G-Y-I-P-G-E-G-H-N-L-Q-E-H-S-V-V-M-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-L-R-G-V-L-D-T-Q-G-V-K-N-R-K-Q-R-R-S-K-Y-G-A-K-R-P-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-S-A-E-K-R-E-V-L-P-D-P-K-F-G-N-I-V-I-T-K-F-M-N-S-V-M-Y-A-G-K-K-S-V-A-E-G-I-V-Y-G-A-L-G-I-I-E-T-K-T-K-Q-N-P-L-G-V-F-E-Q-A-L-E-N-V-M-P-T-I-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-S-T-R-R-Q-A-L-G-I-R-W-L-I-S-A-A-R-E-R-N-E-K-T-M-T-E-R-L-S-A-E-L-L-D-A-S-N-N-R-G-N-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-R-A-F-S-H-Y-R-W


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-N-G-Q-N-I-R-I-R-L-K-A-F-D-H-R-I-L-D-T-S-T-R-E-I-V-N-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-I-E-K-F-T-V-N-R-S-P-H-V-D-K-K-S-R-E-Q-F-E-M-R-T-H-K-R-L-L-D-I-V-D-P-T-P-Q-T-V-D-A-L-M-K-L-D-L-A-A-G-V-D-V-E-I-K-L


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-K-N-I-E-P-R-H-Y-D-V-I-V-A-P-V-V-T-E-K-A-T-L-A-S-E-H-N-K-V-L-F-K-V-A-A-K-A-T-K-P-Q-I-K-E-A-I-E-K-L-F-D-V-K-V-K-S-V-N-T-L-V-R-K-G-K-T-K-V-F-R-G-N-L-G-S-Q-S-N-T-K-R-A-I-V-T-L-E-E-G-H-R-I-D-V-T-T-G-L


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-V-R-S-V-W-K-G-P-F-V-E-G-S-L-L-K-K-A-D-A-A-R-A-S-G-R-H-D-V-I-K-I-W-S-R-R-S-T-I-L-P-Q-F-V-G-L-T-F-G-V-Y-N-G-Q-K-H-V-P-V-A-V-N-E-E-M-V-G-H-K-F-G-E-F-S-P-T-R-T-F-H-G-H-S-G-D-K-K-A-K-K-A


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-K-P-K-R-E-R-S-L-A-E-N-E-A-K-A-V-A-R-M-L-R-V-S-P-Q-K-L-N-L-V-A-Q-L-I-R-G-R-K-A-A-A-A-L-A-D-L-Q-F-S-R-K-R-I-A-V-D-V-K-K-C-L-E-S-A-I-A-N-A-E-N-N-H-D-L-D-V-D-D-L-V-V-A-Q-A-F-V-G-N-G-L-V-M-K-R-F-A-A-R-G-R-G-R-S-G-R-V-Y-K-P-F-S-Q-L-T-I-I-V-R-Q-V-E-A-E-A-A-A-A


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-Q-P-K-K-T-K-F-R-K-A-H-K-G-R-I-H-G-V-A-S-S-G-A-T-L-A-F-G-Q-Y-G-L-K-A-T-E-P-E-R-V-T-A-R-Q-I-E-A-A-R-R-A-L-T-R-H-M-K-R-A-G-R-V-W-I-R-V-F-P-D-L-P-V-S-K-K-P-A-E-V-R-M-G-S-G-K-G-S-P-E-L-W-V-A-R-V-K-P-G-R-V-L-F-E-I-D-G-V-N-T-Q-T-A-R-E-A-L-T-L-A-A-A-K-L-P-I-K-T-R-F-V-E-R-I-A-E


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-T-L-Q-G-V-V-V-S-D-K-T-A-K-T-V-V-V-R-V-D-R-R-F-T-H-P-I-Y-K-K-T-I-R-R-S-K-N-Y-H-A-H-D-E-N-N-E-F-K-P-G-D-M-V-W-I-E-E-S-K-P-I-S-K-L-K-R-W-V-V-I-R-G-E-H-K-K-S-A


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-N-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-T-I-G-D-I-I-V-V-S-I-K-E-A-I-P-R-G-K-V-K-K-G-D-V-M-K-A-V-V-V-R-V-R-K-D-I-R-R-A-D-G-S-V-I-R-F-D-R-N-A-A-V-L-I-N-N-Q-S-E-P-V-G-T-R-I-F-G-P-V-P-R-E-L-R-A-K-N-H-M-K-I-I-S-L-A-P-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-K-G-D-K-V-V-V-L-T-G-R-D-K-G-R-T-G-E-V-F-E-V-R-P-D-A-G-T-A-L-V-R-G-I-N-M-V-K-R-H-Q-K-Q-T-Q-A-Q-E-G-G-I-I-S-K-E-A-P-I-Q-L-S-N-I-A-Y-V-G-K-D-G-K-P-T-R-V-G-F-K-I-L-A-D-G-K-K-V-R-I-A-K-S-S-G-A-E-I-D-G


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-E-A-A-Y-T-P-R-L-R-A-E-Y-D-A-K-I-R-T-A-M-T-E-K-F-G-Y-E-N-V-M-Q-V-P-R-L-D-K-V-V-L-N-M-G-V-G-D-S-V-N-D-R-K-K-A-E-T-A-A-A-E-L-T-Q-I-A-G-Q-K-A-I-V-T-Y-S-R-I-A-I-A-T-F-K-L-R-E-N-Q-P-I-G-C-K-V-T-L-R-K-A-R-M-Y-E-F-I-D-R-L-V-T-V-A-L-P-R-V-R-D-F-R-G-L-N-P-K-S-F-D-G-R-G-N-Y-S-L-G-I-K-E-H-I-I-F-P-E-I-D-F-D-K-V-T-E-A-R-G-M-D-I-T-V-C-T-T-A-K-T-D-E-E-A-R-A-L-L-T-A-F-N-F-P-F-R-Q


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-S-I-E-K-N-N-R-R-K-R-M-V-K-N-A-A-P-K-R-E-R-L-K-A-I-I-A-D-K-T-L-P-M-E-E-R-F-A-A-T-L-K-L-A-E-M-P-R-N-S-S-A-T-R-V-R-L-R-C-E-L-S-G-R-P-R-S-N-Y-R-K-N-K-L-S-R-I-A-L-R-E-L-G-S-K-G-M-V-P-G-L-V-K-S-S-W


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-T-H-D-P-I-S-D-L-I-T-R-I-R-N-A-Q-M-R-S-K-T-K-V-S-T-P-G-S-R-M-R-E-N-V-L-E-V-L-K-S-E-G-Y-I-R-G-Y-A-T-V-E-H-S-S-G-R-S-E-I-E-I-E-L-K-Y-F-D-G-E-P-V-I-R-E-I-E-R-V-S-K-P-G-R-R-V-Y-A-S-V-K-N-L-P-R-V-N-N-G-L-G-I-S-V-L-S-T-P-K-G-I-M-A-D-H-S-A-R-D-A-N-V-G-G-E-V-L-F-T-V-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-R-P-V-A-V-P-S-G-V-T-A-T-V-D-G-Q-T-V-K-M-K-G-P-K-G-Q-L-Q-F-V-V-H-D-D-V-E-V-K-L-E-S-G-Q-I-K-V-K-P-R-L-E-T-N-R-A-R-A-L-Y-G-T-A-R-A-Q-V-A-N-L-V-E-G-V-T-K-G-F-E-K-K-L-E-I-T-G-V-G-Y-R-A-A-M-Q-G-K-N-L-Q-L-A-L-G-Y-S-H-D-V-I-Y-T-I-P-E-G-I-T-I-T-V-P-K-P-T-E-I-T-V-T-G-S-D-I-Q-R-V-G-Q-V-A-A-E-I-R-S-Y-R-P-P-E-P-Y-K-G-K-G-V-K-Y-V-G-E-F-I-F-R-K-E-G-K-K-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-K-A-K-V-T-N-A-R-R-K-R-S-V-R-L-K-L-R-R-S-G-G-G-R-P-R-L-S-V-F-R-S-S-K-H-I-Y-A-Q-V-I-D-D-L-K-G-E-T-L-A-S-A-S-S-L-E-K-S-M-R-D-G-G-K-T-G-A-D-I-D-A-A-K-A-V-G-K-L-L-A-E-R-A-A-E-K-G-V-K-E-V-V-F-D-R-G-S-Y-L-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-S-G-L-S-F


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-E-R-E-Q-R-G-G-R-D-Q-R-G-G-G-R-E-R-K-E-R-E-E-R-D-S-E-F-V-D-K-L-V-H-I-N-R-V-A-K-V-V-K-G-G-K-R-F-G-F-A-A-L-V-V-I-G-D-Q-K-G-R-A-G-F-G-H-G-K-A-R-E-V-P-E-A-I-R-K-A-T-E-S-A-K-R-N-L-T-R-V-S-L-R-E-G-R-T-L-H-H-D-I-A-G-R-H-G-A-G-R-V-Y-L-R-A-A-P-A-G-T-G-I-I-A-G-G-P-M-R-A-V-F-E-T-L-G-V-Q-D-V-V-A-K-S-I-G-S-S-N-P-Y-N-M-V-R-A-T-F-D-A-L-K-H-Q-D-S-P-R-S-V-A-A-R-R-N-I-K-V-S-T-L-Q-S-R-R-I-G-G-D-A-E-A-A-A-D


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-S-D-I-A-D-N-A-G-S-R-K-K-R-M-R-V-G-R-G-I-G-S-G-K-G-K-Q-S-G-R-G-G-K-G-Q-T-A-R-S-G-V-R-I-K-G-F-E-G-G-Q-M-P-M-H-R-R-L-P-K-R-G-F-N-N-I-F-R-V-E-F-A-E-I-N-L-D-R-L-Q-E-A-V-D-A-K-K-I-D-A-G-S-V-V-N-V-E-A-L-V-K-G-G-V-L-R-R-A-K-G-G-L-R-L-L-G-R-G-E-L-K-S-K-L-N-I-E-V-H-G-A-T-K-T-A-I-A-A-V-E-K-A-G-G-S-V-K-I-L-A-P-A-K-E-E-G-E-A-A


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-T-N-K-R-V-L-I-A-L-Q-Y-I-H-G-I-G-Q-K-I-A-G-E-I-L-E-K-V-K-I-P-V-D-R-R-V-S-Q-L-S-D-A-E-V-L-Q-I-R-E-V-I-D-R-D-Y-L-V-E-G-D-L-R-R-E-V-G-I-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-H-T-N-A-R-T-R-K-G-P-A-K-A-I-A-G-K-K-K


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-N-D-E-N-R-S-G-S-P-T-G-P-N-T-S-V-I-T-K-V-K-P-K-T-K-R-P-N-L-Y-R-V-L-I-L-N-D-D-Y-T-P-M-E-F-V-V-H-V-L-E-K-F-F-Q-K-D-V-E-A-A-T-K-I-M-L-H-V-H-H-H-G-I-G-E-C-G-V-F-T-Y-E-I-A-E-T-K-V-T-Q-V-M-D-F-A-R-K-H-Q-H-P-L-Q-C-V-M-E-K-K


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-A-L-I-L-P-L-V-D-A-A-T-H-W-P-E-R-G-G-L-V-G-L-D-L-G-T-K-T-I-G-V-A-V-S-N-P-D-R-R-L-A-T-G-V-E-T-I-Q-R-K-A-F-K-Q-D-A-A-R-L-L-A-I-A-A-E-R-K-V-V-G-F-V-L-G-L-P-I-N-M-D-G-S-E-G-P-R-A-Q-S-T-R-A-F-A-R-N-L-A-N-L-T-T-L-P-I-G-L-W-D-E-R-L-S-T-A-A-V-E-R-E-L-I-G-M-D-V-S-R-A-K-R-A-E-V-I-D-E-H-A-A-I-F-I-L-Q-G-A-L-D-R-L-A-N-L-R-T-G-N-G


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-R-E-F-A-M-K-G-N-V-V-D-L-A-V-G-V-I-I-G-A-A-F-G-A-I-V-T-S-L-V-G-D-V-I-M-P-L-I-G-A-V-T-G-G-L-D-F-S-N-Y-F-T-P-L-S-K-A-V-T-A-T-N-L-A-D-A-K-K-Q-G-A-V-L-A-W-G-S-F-L-T-L-T-I-N-F-I-I-I-A-F-V-L-F-L-V-I-R-A-I-N-T-L-K-R-K-E-E-A-A-P-A-A-P-P-K-P-S-A-E-V-E-L-L-T-E-I-R-D-L-L-K-K-S


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-N-C-N-S-L-D-T-Q-V-K-D-S-R-P-T-E-D-S-S-V-I-R-R-R-R-V-C-V-A-C-N-F-R-F-T-T-F-E-R-V-Q-L-R-E-L-T-V-I-K-R-N-G-R-R-V-P-F-D-R-D-K-L-M-R-S-V-Q-I-S-L-R-K-R-Q-V-E-P-E-R-V-E-K-M-V-S-T-I-V-R-E-L-E-T-G-G-E-A-E-I-S-S-E-V-I-G-E-T-V-M-E-H-L-R-T-L-D-D-V-A-Y-V-R-F-A-S-V-Y-R-N-F-R-E-A-K-D-F-A-D-V-L-G-E-L-S-G-E-E-E-A-R-L-A-A-I-R-K


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-A-D-A-R-R-A-P-L-K-D-Q-T-D-I-S-G-A-R-A-L-I-V-E-A-R-F-Y-D-D-L-Q-D-A-L-L-D-G-A-V-A-E-L-K-A-A-G-L-T-H-D-V-I-T-V-P-G-A-L-E-I-P-A-A-V-A-I-A-V-D-A-A-A-A-N-G-K-P-Y-D-A-V-I-A-L-G-C-V-I-R-G-D-T-I-H-F-E-I-V-S-Q-E-S-S-R-A-L-M-D-L-A-V-S-R-K-L-P-L-G-N-G-I-L-T-V-N-T-E-A-Q-A-W-A-R-A-R-A-S-E-L-N-K-G-G-D-A-A-R-A-A-L-A-M-L-R-I-K-R-R-L-A-R-A


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-A-D-N-N-K-K-P-A-G-L-T-E-K-K-A-N-R-R-G-A-A-R-L-A-A-V-Q-A-L-Y-Q-M-D-I-A-G-A-G-I-N-D-I-F-A-E-F-E-S-H-W-L-G-N-E-V-E-G-D-T-Y-L-P-A-E-A-A-F-F-R-D-V-V-S-G-V-V-R-D-Q-K-K-L-D-P-L-I-D-E-A-L-S-K-G-W-P-L-K-R-I-E-A-I-L-R-A-V-L-R-A-G-A-Y-E-L-Q-H-R-K-D-V-P-G-R-V-V-V-S-E-Y-V-D-V-A-N-A-F-V-D-R-E-E-T-G-M-V-N-A-V-L-D-Q-I-G-R-Q-F-R-G-D-E-F-G-R-G


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-S-A-K-P-A-E-V-T-K-K-W-V-L-I-D-A-K-G-L-V-V-G-R-L-A-T-I-V-A-M-R-L-R-G-K-H-L-P-T-Y-T-P-H-V-D-C-G-D-N-V-I-I-I-N-A-Q-H-A-V-L-T-G-R-K-R-E-Q-K-T-Y-Y-K-H-T-G-Y-V-G-H-V-K-E-R-T-A-R-Q-I-L-E-G-K-H-P-E-R-V-L-E-K-A-V-E-R-M-I-P-R-G-P-L-G-R-V-Q-M-G-N-L-R-V-Y-G-G-A-D-H-P-H-E-A-Q-Q-P-E-K-I-D-I-A-K-L-N-R-K-N-T-R-A-A


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-M-P-T-G-N-F-D-L-N-E-V-K-R-R-M-Q-G-A-V-Q-S-L-K-H-E-L-G-G-L-R-T-G-R-A-S-A-S-M-L-D-P-V-Q-V-E-A-Y-G-S-H-M-P-L-N-Q-L-A-T-V-S-V-P-E-P-R-L-I-S-V-Q-V-W-D-K-S-M-V-K-A-V-E-K-A-I-V-D-S-N-L-G-L-S-P-A-T-E-G-Q-V-L-R-L-R-I-P-E-L-N-E-E-R-R-K-E-L-V-K-V-A-H-K-Y-A-E-A-A-K-V-A-A-R-H-V-R-R-D-G-L-D-V-L-K-K-L-E-K-N-H-E-M-S-E-D-D-Q-K-R-H-A-D-E-V-Q-K-V-T-D-G-T-I-A-E-I-D-Q-L-L-A-A-K-E-K-E-I-L-T-V


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-L-S-I-W-H-W-I-L-V-I-A-V-V-L-L-L-F-G-R-G-K-I-S-D-L-M-G-D-V-A-Q-G-I-K-A-F-K-K-G-M-Q-D-D-D-K-P-A-D-K-P-E-P-A-K-S-I-E-H-N-A-A-P-T-A-A-R-S-D-V-G-S-K-A-V


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-W-S-E-L-V-L-I-G-V-V-A-L-I-A-I-G-P-K-E-L-P-G-V-L-R-M-V-G-Q-W-M-G-K-A-R-K-M-A-A-E-F-Q-G-Q-F-Q-E-A-M-R-E-A-E-M-A-D-L-K-K-S-F-D-E-V-K-E-A-A-S-G-F-A-G-N-N-L-M-T-S-L-Q-K-D-V-S-D-A-L-R-V-D-A-L-D-K-P-A-E-T-S-S-T-T-A-I-E-A-P-A-T-S-S-E-A-L-T-T-P-T-T-P-E-A-P-T-P-E-T-F-V-E-A-E-A-H-A-A-V-N-E-P-L-A-I-T-R-E-V-E-Q-A-P-V-V-A-Q-D-T-A-P-S-E-A-I-K-D-A-K-A-S


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-V-N-K-V-I-L-V-G-N-L-G-K-D-P-E-I-R-R-T-Q-D-G-R-P-I-A-N-L-S-I-A-T-S-E-T-W-R-D-K-N-S-G-E-R-K-E-K-T-E-W-H-R-V-V-I-F-N-E-G-L-C-K-V-A-E-Q-Y-L-K-K-G-A-K-V-Y-I-E-G-A-L-Q-T-R-K-W-T-D-Q-S-G-V-E-K-Y-S-T-E-V-V-L-Q-G-F-N-S-T-L-T-M-L-D-G-R-G-G-G-G-G-G-S-F-G-E-E-P-G-G-D-F-G-S-S-G-P-V-S-S-A-P-R-R-A-V-A-A-G-G-G-G-R-N-S-D-M-D-D-D-I-P-F


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-A-D-R-A-Q-N-L-Q-D-T-F-L-N-H-V-R-K-T-K-T-P-L-T-I-F-L-V-N-G-V-K-L-Q-G-I-V-T-W-F-D-N-F-C-L-L-L-R-R-D-G-H-S-Q-L-V-Y-K-H-A-I-S-T-I-M-P-G-A-P-I-Q-L-F-E-G-G-E-D-Q-P-A


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-R-V-I-A-S-S-I-R-K-G-N-V-I-E-Q-D-G-K-L-Y-V-V-V-S-A-E-N-I-H-P-G-K-G-T-P-V-S-Q-I-E-M-R-R-I-S-D-G-V-K-I-S-E-R-Y-K-T-T-D-Q-V-E-K-A-T-I-E-E-R-N-F-T-F-L-Y-E-D-G-D-G-Y-H-F-M-N-P-E-T-Y-D-Q-V-Q-V-S-K-D-V-V-G-D-A-A-A-Y-L-Q-P-D-M-T-V-K-L-S-T-H-D-V-N-V-V-S-L-A-L-P-Q-R-V-T-L-E-V-V-E-T-E-P-V-T-K-G-Q-T-A-S-S-S-Y-K-P-A-V-L-S-N-G-I-R-T-T-V-P-P-H-I-A-V-G-T-R-I-V-V-M-T-E-D-G-S-Y-S-E-R-A-K-D


### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-G-L-L-R-L-L-R-G-N-K-A-S-A-P-V-A-R-E-R-L-Q-I-L-L-A-H-E-R-G-M-R-G-Q-P-D-L-L-G-V-L-R-E-E-I-L-A-V-V-S-K-H-V-T-L-D-P-T-K-V-I-V-R-L-E-R-G-D-E-V-S-T-L-E-V-D-I-E-V-P-N-D-L-E-R-K-R-V-A-V-A


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-D-I-G-E-R-V-K-K-I-V-V-E-H-L-G-V-E-P-E-K-V-V-D-A-A-S-F-I-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-F-E-E-E-F-G-C-E-I-P-D-D-A-A-E-T-I-L-T-V-G-D-A-T-K-F-L-E-K-N-A-K-S


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-L-Y-E-H-V-F-L-A-R-Q-D-A-S-P-Q-Q-V-E-E-L-T-A-Q-M-T-G-I-V-E-G-L-G-G-K-V-T-K-T-E-N-W-G-V-R-S-L-T-Y-R-M-N-K-N-R-K-A-H-F-V-L-L-N-I-D-A-P-S-A-A-I-A-E-I-E-R-Q-E-R-I-S-E-D-V-I-R-Y-L-S-V-R-V-E-E-L-E-E-G-P-S-A-M-M-R-K-A-D-R-D-R-E-R-D-D-R-G-G-G-F-R-G-E-R-E-G-G-F-R-G-D-R-E-G-G-F-R-G-G-D-R-D-G-G-G-F-R-G-D-R-G-P-R-R-P-R-E-E-A-E-T-A-T-D-G-E


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-E-A-G-A-R-R-P-F-F-R-R-R-K-S-C-P-F-T-G-A-N-A-P-K-I-D-Y-K-D-S-K-L-L-M-R-Y-V-S-E-R-G-K-I-V-P-S-R-I-T-A-V-S-A-K-K-Q-R-E-L-A-R-A-I-K-R-A-R-F-L-G-L-L-P-Y-V-I-R


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-E-N-T-Q-V-D-V-S-R-L-T-F-E-R-A-I-E-E-L-E-T-I-V-K-R-L-E-D-G-K-V-P-L-E-E-S-V-T-I-Y-E-R-G-E-A-L-K-R-R-C-E-E-L-L-R-Q-A-E-A-R-V-D-K-I-T-T-D-A-S-G-Q-A-T-G-T-A-P-L-D-V-Q


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-R-M-G-G-S-F-V-V-L-S-G-V-I-A-I-V-V-G-S-V-L-G-G-C-A-R-Y-F-I-S-G-A-V-A-R-R-L-G-E-T-F-P-W-G-T-M-T-I-N-V-T-G-A-F-L-I-G-I-F-G-A-L-A-T-H-P-G-S-M-F-A-S-P-N-P-W-L-F-A-V-T-G-F-L-G-C-Y-T-T-V-S-S-F-S-L-Q-T-L-T-L-A-R-N-G-E-P-M-H-A-L-G-N-V-A-F-S-V-G-L-C-L-A-A-V-S-C-G-F-L-L-A-D-G-L-G-G


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-V-P-S-S-A-E-R-W-R-S-A-M-L-Y-A-W-V-S-A-G-S-V-V-G-G-L-T-R-Y-L-V-G-L-A-L-D-T-G-P-G-F-P-F-A-T-L-F-I-N-A-T-G-S-L-I-I-G-F-Y-A-T-L-T-G-P-D-G-R-M-L-A-R-P-E-H-R-Q-F-V-M-T-G-F-C-G-G-Y-T-T-F-S-A-F-S-L-E-T-F-R-L-F-H-G-G-M-K-Y-I-A-L-A-Y-V-A-S-S-V-V-C-W-L-V-S-V-W-L-G-H-I-M-A-S-R-Y-N-R-L-K-R-S


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-N-D-A-V-T-K-P-K-T-R-T-K-T-K-V-E-R-P-K-L-H-K-V-I-L-I-N-D-D-Y-T-P-R-E-F-V-T-M-I-L-K-A-E-F-R-M-T-E-D-Q-A-Y-K-V-M-I-T-A-H-K-L-G-A-C-V-V-A-V-F-T-R-D-V-A-E-T-K-A-T-R-A-T-D-A-G-R-A-K-G-Y-P-L-L-F-T-T-E-P-E-E


### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-R-S-L-H-D-I-E-A-T-D-H-F-V-D-W-G-N-S-T-S-H-R-L-L-T-D-K-D-G-M-G-F-S-I-C-H-T-I-V-R-A-N-T-V-S-L-L-Q-Y-R-N-H-L-E-A-C-F-C-I-G-G-E-G-E-V-E-D-M-D-G-N-V-F-P-I-R-R-G-D-M-Y-V-L-D-K-H-D-K-H-L-L-R-G-G-P-D-K-D-M-I-L-V-S-I-F-N-P-P-L-T-G-T-E-R-H-K-L-D-D-P-A-G-S-T-Y


### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-E-I-H-P-D-Y-H-T-I-K-V-V-M-T-D-G-T-E-Y-L-T-R-S-T-W-G-K-E-G-D-T-L-N-L-D-I-D-P-K-S-H-P-A-W-T-G-G-N-A-Q-I-M-D-R-G-G-R-V-S-R-F-Q-K-K-F-S-G-F-L-K-K-D


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-L-I-Q-F-E-G-L-V-T-E-I-L-P-D-A-R-Y-R-V-Q-L-D-A-G-H-E-I-V-A-Y-T-A-G-K-M-K-K-N-R-I-K-T-L-A-G-D-R-V-T-V-E-M-S-P-Y-D-L-E-K-G-R-L-I-F-R-H-K-D-E-R-P-A-T-S-G-G-P-P-R-G-G-A-Q-R-G-G-Q-F-R-R-R


### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-D-D-Q-V-K-M-P-T-G-P-L-K-T-C-P-I-C-G-K-P-A-V-Q-A-T-H-P-F-C-S-S-R-C-R-D-V-D-L-N-R-W-L-K-G-S-Y-V-I-P-G-R-D-D-E-V-D-D-V-E


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-F-F-D-P-E-T-W-V-A-I-A-F-V-I-L-M-V-V-F-G-Y-L-G-V-F-K-S-A-M-T-A-L-D-H-R-A-A-R-I-K-A-E-L-D-D-A-T-R-L-K-Q-E-A-A-K-V-L-A-D-Y-K-A-R-S-A-T-A-E-R-E-A-A-D-I-I-A-N-A-K-V-E-A-E-R-I-A-T-E-A-K-A-K-M-E-D-F-V-A-R-R-T-K-T-A-E-S-K-I-A-L-A-E-A-Q-A-V-A-D-V-R-A-A-A-A-E-A-A-V-Q-A-A-S-T-I-L-S-Q-S-V-K-G-Q-V-A-D-D-L-L-A-K-S-I-S-E-V-R-Q-K-L-N


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-T-S-A-K-K-A-T-R-K-I-A-R-R-T-A-V-N-K-S-R-R-T-Q-M-R-G-A-V-R-N-V-E-E-A-I-K-T-G-D-R-A-A-A-V-K-A-L-A-N-A-E-P-A-L-M-R-A-A-Q-R-N-I-I-H-K-N-N-A-S-R-K-V-S-R-L-T-A-Q-I-A-K-L-A-K


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-G-A-D-A-S-A-F-S-F-R-T-K-T-M-S-H-P-N-L-P-M-T-E-V-L-V-V-A-D-C-W-Q-R-E-P-D-S-E-A-V-I-Q-R-A-V-A-A-A-A-E-S-V-D-E-D-V-A-E-A-E-V-A-V-M-L-T-D-D-A-G-I-R-T-L-N-S-N-W-R-G-I-D-K-P-T-N-V-L-S-F-P-A-L-Q-P-E-G-E-W-K-E-G-D-A-P-R-M-L-G-D-I-A-I-A-Y-E-T-M-R-R-E-A-D-E-E-K-K-P-F-D-H-H-L-S-H-L-A-V-H-G-F-L-H-L-I-G-Y-D-H-E-N-D-D-D-A-E-E-M-E-A-L-E-T-Q-I-L-A-H-L-G-I-P-D-P-Y-A-D-R-P-G-T-H


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-R-H-H-Q-K-K-S-S-A-S-G-G-G-S-Q-R-Q-L-R-V-G-E-Q-V-R-H-A-M-A-E-I-L-A-Q-G-N-V-H-D-A-D-L-E-G-H-I-V-T-V-P-E-V-R-M-S-P-D-L-K-L-A-T-I-Y-V-M-P-L-G-G-R-D-T-E-I-V-I-A-A-L-E-R-N-K-K-F-L-R-G-E-V-A-R-R-V-N-L-K-F-A-P-D-V-R-F-R-V-D-E-R-F-D-E-A-E-R-I-E-K-L-L-R-T-P-A-V-Q-K-D-L-E-Q-D-P-D-S-D-R-E-E-E-Q


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-I-A-A-E-R-K-A-E-V-I-K-T-N-A-T-K-A-G-D-T-G-S-P-E-V-Q-V-A-I-L-S-E-R-I-N-N-L-T-S-H-F-K-T-H-V-K-D-N-H-S-R-R-G-L-L-K-L-V-S-T-R-R-S-L-L-D-Y-L-K-K-R-D-E-A-R-Y-K-A-L-L-E-K-H-N-I-R-R


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-R-R-P-N-K-A-P-P-A-A-S-K-D-G-P-R-I-N-D-D-I-R-N-A-Q-I-Q-L-I-D-Q-T-G-D-N-K-G-T-V-E-T-V-V-A-I-K-M-A-Q-E-A-G-M-D-L-V-E-I-S-P-N-T-S-P-P-V-C-K-I-M-D-Y-G-K-Y-K-Y-S-A-Q-K-K-A-A-E-A-R-K-R-Q-K-T-V-E-I-K-E-I-K-L-R-P-M-I-D-D-H-D-Y-D-V-K-M-R-A-M-Q-R-F-F-E-E-G-D-K-V-K-I-T-L-R-Y-R-G-R-E-M-A-H-Q-E-I-G-T-K-L-L-D-K-I-K-T-D-V-A-E-L-A-K-V-E-Q-D-A-R-F-E-G-R-Q-V-V-M-V-L-A-P-R


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-S-R-V-K-R-G-V-T-A-H-A-K-H-K-K-V-Y-K-A-A-K-G-F-Y-G-R-R-K-N-T-I-R-A-A-K-P-A-V-E-K-A-Q-Q-Y-A-F-R-D-R-K-R-K-K-R-T-F-R-A-L-W-I-Q-R-L-N-A-A-V-R-P-F-G-L-T-Y-S-R-F-I-D-G-L-A-K-S-G-I-T-V-D-R-K-V-L-S-D-L-A-I-N-E-P-A-S-F-Q-A-I-A-E-K-A-K-A-A-L-A-A


### FUNCTION Transcriptional regulator ### SEQUENCE -M-Q-R-I-T-I-T-I-E-D-D-L-L-A-E-I-D-A-A-A-A-A-R-G-Y-Q-N-R-S-E-I-I-R-D-L-A-R-A-G-L-Q-Q-T-S-E-D-T-A-Q-T-G-P-C-V-A-G-L-V-Y-V-Y-D-H-A-A-R-D-L-S-K-R-L-V-Q-E-F-H-G-H-H-D-L-A-L-A-T-L-H-V-H-L-D-D-N-N-C-M-E-M-T-A-L-R-G-A-A-D-E-V-R-H-F-A-D-H-I-I-A-E-R-G-V-R-Y-G-R-V-V-M-I-P-T-G-E-G-K-P-A-K-A-R-K-H-G-H-R-H-E


### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-T-N-G-N-G-T-P-P-E-A-A-P-A-P-Q-L-N-V-L-A-Q-Y-T-K-D-L-S-F-E-N-P-N-A-P-S-S-L-Q-Q-Q-G-Q-P-P-Q-I-N-I-Q-I-N-V-G-A-N-N-L-S-E-Q-E-F-E-V-T-L-S-V-E-G-K-A-E-T-A-G-K-V-M-F-S-F-E-L-A-Y-A-G-V-F-R-I-V-N-V-P-K-E-N-L-H-P-L-V-M-I-E-C-P-R-L-L-F-P-F-A-R-E-I-I-A-T-A-V-R-D-G-G-F-P-P-L-M-L-D-P-V-D-F-V-G-L-Y-R-Q-N-M-E-R-Q-M-A-A-G-G-Q-A-G-Q-A


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-L-I-K-Q-L-E-Q-E-Q-F-D-K-L-S-A-G-K-D-I-P-E-F-G-P-G-D-T-V-I-V-N-V-K-V-V-E-G-D-R-T-R-V-Q-A-Y-E-G-V-C-I-G-R-S-G-G-G-L-N-E-S-F-T-V-R-K-I-S-Y-G-E-G-V-E-R-V-F-P-V-M-S-P-M-I-D-S-I-K-V-V-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-N-L-R-G-K-S-A-R-I-V-E-K-Q-D-R-Q-A-A-V-G-E


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-A-L-V-C-V-A-R-I-G-A-A-H-G-V-R-G-A-V-K-L-W-T-F-T-E-D-P-F-A-I-K-R-Y-G-P-L-L-S-K-D-G-K-R-Q-F-E-V-A-Q-A-R-E-A-K-D-H-L-V-A-T-F-K-G-V-T-T-R-D-E-A-E-R-L-N-G-I-E-L-Y-V-A-R-E-K-L-P-A-T-D-E-D-E-Y-Y-H-T-D-L-I-G-L-A-A-V-T-T-D-G-E-P-L-G-R-V-L-A-I-H-N-F-G-A-G-D-I-I-E-I-A-P-P-K-G-A-S-L-L-L-P-F-S-N-A-V-V-P-E-V-D-V-A-G-G-R-V-V-V-A-L-P-Q-E-I-A-G-D-E-A-E-E-R


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-A-E-D-T-S-V-S-G-V-S-G-R-Y-A-T-A-L-F-E-L-A-R-D-Q-K-A-V-D-E-V-K-A-D-L-D-R-F-E-A-L-L-G-E-S-A-D-L-K-R-L-V-R-S-P-V-F-A-A-D-A-Q-S-R-A-L-T-A-V-L-D-K-V-G-I-A-G-I-S-A-N-F-L-K-V-L-T-A-N-R-R-L-F-V-V-A-D-V-I-R-A-Y-R-A-L-V-A-K-F-K-G-E-A-T-A-D-V-T-V-A-E-A-L-S-D-K-N-L-D-A-L-K-V-A-L-K-S-V-T-G-K-D-V-A-L-N-V-K-V-D-P-S-I-I-G-G-L-V-V-K-L-G-S-R-M-V-D-G-S-L-R-T-K-L-N-S-I-K-H-A-M-K-E-A-G


### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-A-R-Y-E-D-L-P-Y-R-T-C-V-G-V-M-L-I-N-A-K-G-L-V-F-I-G-R-R-A-G-G-I-E-H-I-D-D-T-H-V-W-Q-M-P-Q-G-G-V-D-P-G-E-D-T-W-A-A-A-K-R-E-L-Y-E-E-T-S-V-R-S-V-E-R-L-G-E-V-P-D-W-L-I-Y-D-I-P-R-T-V-A-G-R-A-W-K-G-R-Y-R-G-Q-R-Q-K-W-F-A-V-R-F-T-G-K-D-S-E-I-N-V-E-N-P-G-G-G-H-K-A-E-F-V-S-W-R-W-E-P-M-K-N-L-P-G-L-I-I-P-F-K-R-P-V-Y-E-R-V-V-K-E-F-S-A-L-A-E-E


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-R-V-A-V-I-A-V-G-R-L-K-Q-G-P-E-R-E-L-A-D-R-Y-F-E-R-F-D-E-A-G-R-K-L-G-F-R-E-L-S-I-H-E-I-P-E-S-R-A-R-D-A-A-T-R-M-A-E-E-A-A-A-I-G-A-Y-I-P-D-K-S-I-L-V-A-L-D-E-R-G-Q-N-L-D-S-T-V-F-A-R-H-L-G-R-W-R-D-E-G-A-G-H-T-I-F-V-I-G-G-A-D-G-L-S-P-E-L-R-R-K-A-K-L-A-I-A-F-G-S-A-T-W-P-H-Q-M-V-R-V-M-L-L-E-Q-L-Y-R-A-A-T-I-L-A-G-H-P-Y-H-R-A


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-I-K-T-G-G-R-Q-Y-R-V-A-P-D-D-V-L-E-V-G-K-I-E-G-E-V-G-S-I-V-Q-L-N-E-V-L-V-V-G-G-D-T-P-I-L-G-L-P-T-V-A-G-A-S-V-A-V-E-V-L-D-H-K-R-G-P-K-V-I-A-F-K-K-R-R-R-K-N-S-R-R-K-R-G-Y-R-D-E-I-T-V-L-R-V-S-E-I-L-T-D-N-A-K-P-T-K-G-P-R-P-K-K-E-K-V-A-K-E-A-T-K-E-D-A-A-A


### FUNCTION Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'--3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism ### SEQUENCE -M-E-D-L-S-F-R-H-P-V-R-A-R-A-D-G-A-R-R-S-A-I-V-G-I-V-A-S-G-N-L-E-V-L-V-E-R-V-L-P-D-A-E-C-A-I-D-I-K-T-A-A-V-G-F-G-E-V-W-R-A-V-I-G-D-F-V-E-R-Y-S-P-G-G-L-K-F-S-I-N-D-G-G-A-R-P-D-T-V-S-L-R-L-A-Q-A-V-R-S-I-A-E-N-G-Q


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-K-S-I-E-V-K-G-T-A-R-T-I-A-E-R-S-S-E-Q-A-R-A-L-K-E-I-R-K-N-G-G-V-P-C-V-L-Y-G-A-G-E-V-V-H-F-T-V-T-N-E-G-L-R-N-L-V-Y-T-P-H-I-Y-V-V-D-L-D-I-D-G-K-K-V-N-A-I-L-K-D-I-Q-F-H-P-V-K-D-N-I-L-H-V-D-F-Y-Q-I-D-E-A-K-P-I-V-M-E-V-P-V-Q-L-E-G-L-A-E-G-V-K-A-G-G-K-L-A-L-Q-M-R-K-I-K-V-K-A-L-Y-N-V-I-P-E-K-L-T-V-N-V-S-H-L-G-L-G-K-T-V-K-V-G-E-L-S-F-E-G-L-E-L-I-S-A-K-E-A-V-V-C-A-V-K-L-T-R-A-A-R-G-A-A-A-A-A-G-K


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-I-K-Y-L-I-V-G-L-G-N-I-G-P-E-Y-H-E-T-R-H-N-I-G-F-M-T-V-E-A-L-A-R-I-N-N-A-P-P-F-I-D-G-R-Y-G-F-T-T-S-F-S-I-K-G-R-Q-L-I-L-L-K-P-S-T-F-M-N-L-S-G-L-A-V-R-Y-W-M-Q-K-E-N-I-P-L-E-N-V-L-I-V-V-D-D-L-A-L-P-F-G-T-L-R-L-K-G-K-G-S-D-A-G-H-N-G-L-K-H-I-A-A-I-L-G-T-Q-N-Y-A-R-L-R-F-G-I-G-N-D-F-P-K-G-G-Q-I-D-Y-V-L-G-H-F-T-D-E-D-R-K-T-M-D-E-R-L-E-T-A-G-E-I-I-K-S-F-C-L-A-G-I-D-I-T-M-N-Q-F-N-K-K


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-K-T-L-L-F-I-G-M-G-S-F-T-G-G-V-L-R-Y-L-I-S-R-Y-V-Q-N-F-L-T-P-S-F-P-L-G-T-L-L-V-N-V-L-G-C-F-A-I-G-L-F-Y-G-L-F-E-R-G-N-L-M-N-P-N-L-R-M-F-L-T-V-G-F-C-G-G-F-T-T-F-S-T-F-M-N-E-N-F-Q-L-I-K-D-D-N-F-F-Y-L-S-L-Y-V-G-L-S-L-F-V-G-F-I-M-L-Y-L-G-Y-S-L-V-K-Q


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-T-G-L-E-I-W-L-L-A-I-G-L-A-M-D-C-F-A-V-S-I-A-S-G-I-I-L-K-R-T-Q-W-R-P-M-L-V-M-A-L-A-F-G-L-F-Q-A-L-M-P-F-I-G-W-M-F-A-K-T-F-S-H-L-I-E-S-V-D-H-W-I-A-F-A-I-L-A-F-L-G-G-R-M-I-L-E-S-F-K-D-E-D-C-R-Q-T-F-N-P-A-S-P-K-V-V-F-T-M-A-I-A-T-S-I-D-A-L-A-I-G-I-S-F-A-L-L-G-I-N-N-Y-T-E-I-L-S-P-I-L-I-I-G-F-V-S-F-V-M-S-L-I-G-L-Y-F-G-I-K-C-G-C-G-C-A-R-K-L-K-A-E-L-W-G-G-I-I-L-V-A-I-G-L-K-I-L-I-E-H-L-F-L-Q


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-E-I-N-G-Q-Q-F-K-A-E-A-G-Q-K-L-F-V-H-H-I-E-G-A-E-N-G-S-T-V-E-F-E-K-V-L-L-V-D-K-D-G-N-V-T-V-G-A-P-T-V-E-G-A-K-V-V-C-Q-V-I-S-N-L-V-K-G-D-K-V-L-V-F-H-K-K-R-R-K-G-Y-R-K-L-N-G-H-R-Q-Q-F-T-E-L-T-I-T-E-V-V-A


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-G-K-S-T-F-L-Q-D-F-K-A-F-A-M-K-G-N-V-I-D-M-A-V-G-V-V-I-G-G-A-F-G-K-I-V-S-S-L-V-A-N-V-I-M-P-P-I-G-L-L-V-G-G-V-N-F-T-D-L-K-W-V-M-K-A-A-E-V-G-A-D-G-K-E-I-A-P-A-V-S-L-D-Y-G-Q-F-L-Q-A-T-F-D-F-L-I-I-A-F-A-I-F-L-F-I-R-L-I-T-K-L-T-T-K-K-A-A-E-E-A-P-A-A-P-P-A-P-P-A-P-T-K-E-E-V-L-L-T-E-I-R-D-L-L-K-E-K-K


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-F-G-I-V-V-S-E-W-N-F-N-I-T-G-A-L-L-N-G-A-V-N-T-L-K-K-H-G-V-K-D-E-N-I-L-V-K-T-V-P-G-S-F-E-L-T-F-G-A-N-Q-M-M-E-N-C-D-V-D-A-I-I-A-I-G-C-V-I-K-G-D-T-P-H-F-D-Y-V-C-M-G-A-T-Q-G-I-T-E-L-N-A-T-G-D-I-P-V-I-Y-G-L-I-T-T-N-T-M-E-Q-A-E-D-R-A-G-G-K-L-G-N-K-G-D-E-C-A-I-S-A-I-K-M-I-D-F-V-W-S-L-N-K


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-K-K-A-N-R-L-D-A-I-K-M-I-I-S-S-K-E-V-G-S-Q-E-E-L-L-Q-E-L-N-R-E-G-F-E-L-T-Q-A-T-L-S-R-D-L-K-Q-L-K-V-A-K-A-A-S-M-N-G-K-Y-V-Y-V-L-P-N-N-I-M-Y-K-R-S-T-D-Q-S-A-G-E-M-L-R-N-N-G-F-I-S-L-Q-F-S-G-N-I-A-V-I-R-T-R-P-G-Y-A-S-S-M-A-Y-D-I-D-N-N-E-F-S-E-I-L-G-T-I-A-G-D-D-T-I-M-L-V-L-R-E-G-V-A-T-S-K-V-R-Q-L-L-S-L-I-I-P-N-I-E


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-N-A-Q-D-I-K-N-G-T-C-I-R-M-D-G-K-L-Y-F-C-I-E-F-L-H-V-K-P-G-K-G-N-T-F-M-R-T-K-L-K-D-V-V-S-G-Y-V-L-E-R-R-F-N-I-G-E-K-L-E-D-V-R-V-E-R-R-P-Y-Q-F-L-Y-K-E-G-E-D-Y-I-F-M-N-Q-E-T-F-D-Q-H-P-I-A-H-D-L-I-N-G-V-D-F-L-L-E-G-A-V-L-D-V-V-S-D-A-S-T-E-T-V-L-Y-A-D-M-P-I-K-V-Q-M-K-V-T-Y-T-E-P-G-M-K-G-D-T-A-T-N-T-L-K-P-A-T-V-E-S-G-A-T-V-R-V-P-L-F-I-S-E-G-E-T-I-E-I-D-T-R-D-G-S-Y-V-G-R-V-K-A


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-N-V-Q-V-I-N-K-S-K-H-P-L-P-A-Y-A-T-E-L-S-A-G-M-D-I-R-A-N-L-S-E-P-I-T-L-A-P-L-Q-R-C-L-V-P-T-G-I-Y-I-A-L-P-Q-G-F-E-A-Q-V-R-P-R-S-G-L-A-I-K-K-G-I-T-V-L-N-S-P-G-T-I-D-A-D-Y-R-G-E-V-C-I-I-L-V-N-L-S-S-E-P-F-V-I-E-D-G-E-R-I-A-Q-M-V-I-A-R-H-E-Q-A-V-W-Q-E-V-E-V-L-D-E-T-E-R-G-A-G-G-F-G-H-T-G-R-G


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-K-S-S-L-K-R-I-R-Q-E-E-T-R-R-L-H-N-R-Y-Y-G-K-T-M-R-N-A-V-R-K-L-R-A-T-T-D-K-K-E-A-V-A-M-Y-P-G-I-T-K-M-L-D-K-L-A-K-T-N-V-I-H-K-N-K-A-N-N-L-K-S-K-L-A-L-Y-I-N-K-L-A


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-I-E-K-K-T-V-C-Q-I-V-E-E-W-L-E-G-K-D-Y-F-L-V-E-V-T-V-S-P-D-D-K-I-V-V-E-I-D-H-A-E-G-V-W-I-E-D-C-V-E-L-S-R-F-I-E-S-K-L-N-R-E-E-E-D-Y-E-L-E-V-G-S-A-G-I-G-Q-P-F-K-V-L-Q-Q-Y-Y-I-H-I-G-Q-E-V-E-V-V-T-R-D-G-R-K-L-A-G-I-L-K-D-A-D-E-E-K-F-T-V-G-V-Q-K-K-V-K-L-E-G-S-K-R-P-K-L-I-E-E-D-E-T-F-T-Y-E-Q-I-K-Y-T-K-Y-L-I-S-F-K


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-E-I-A-S-R-V-K-A-I-I-V-D-K-L-G-V-E-E-S-E-V-T-N-E-A-S-F-T-N-D-L-G-A-D-S-L-D-T-V-E-L-I-M-E-F-E-K-E-F-G-I-S-I-P-D-D-Q-A-E-K-I-G-T-V-G-D-A-V-S-Y-I-E-E-H-A-K


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-V-T-Y-Q-T-E-G-V-K-M-P-D-I-K-K-R-E-T-T-E-W-I-K-N-V-A-A-S-Y-G-K-R-L-G-E-I-A-Y-I-F-C-S-D-E-K-I-L-E-V-N-R-Q-Y-L-Q-H-D-Y-Y-T-D-I-I-T-F-D-Y-C-Q-G-D-R-L-S-G-D-L-F-I-S-L-D-T-I-R-T-N-A-E-Q-F-G-A-A-Y-D-D-E-L-H-R-V-I-I-H-G-I-L-H-L-C-G-I-N-D-K-G-P-G-E-R-E-I-M-E-E-A-E-N-K-A-L-A-M-R


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-Y-L-D-A-A-E-K-Q-E-I-F-G-K-Y-G-K-S-N-S-D-T-G-S-T-E-A-Q-I-A-L-F-S-Y-R-I-S-H-L-T-E-H-M-K-L-N-R-K-D-Y-S-T-E-R-A-L-T-M-L-V-A-K-R-R-R-L-L-N-Y-L-K-D-K-D-I-T-R-Y-R-S-I-V-K-E-L-G-L-R-K


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-E-V-A-G-L-I-K-L-Q-I-K-G-G-A-A-N-P-S-P-P-V-G-P-A-L-G-S-K-G-I-N-I-M-E-F-C-K-Q-F-N-A-R-T-Q-D-K-A-G-K-I-L-P-V-I-I-T-Y-Y-A-D-K-S-F-D-F-V-I-K-T-P-P-V-A-I-Q-L-L-E-V-A-K-V-K-S-G-S-A-E-P-N-R-K-K-V-A-E-L-T-W-E-Q-I-R-T-I-A-Q-D-K-M-V-D-L-N-C-F-T-V-D-A-A-M-R-M-V-A-G-T-A-R-S-M-G-I-A-V-K-G-E-F-P-V-N-N


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-D-L-K-A-F-A-E-Q-L-V-N-L-T-V-K-E-V-N-E-L-A-T-I-L-K-E-E-Y-G-I-E-P-A-A-A-A-V-A-V-A-A-G-P-A-A-G-A-A-A-V-E-E-K-T-S-F-D-V-V-L-K-S-A-G-A-A-K-L-Q-V-V-K-A-V-K-E-A-C-G-L-G-L-K-E-A-K-D-M-V-D-G-A-P-S-V-V-K-E-G-L-A-K-D-E-A-E-S-L-K-K-T-L-E-E-A-G-A-E-V-E-L-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-A-K-P-K-K-R-V-I-L-P-D-P-V-F-N-D-Q-K-V-S-K-F-V-N-H-L-M-Y-D-G-K-K-N-A-S-Y-E-I-F-Y-A-A-L-E-T-V-K-A-K-L-P-N-E-E-K-S-A-L-E-I-W-K-K-A-L-D-N-V-T-P-Q-V-E-V-K-S-R-R-V-G-G-A-T-F-Q-V-P-T-E-I-R-P-D-R-K-E-S-V-S-M-K-N-L-I-L-F-A-R-K-R-G-G-K-S-M-A-D-K-L-A-A-E-I-M-D-A-F-N-E-Q-G-G-A-Y-K-R-K-E-D-M-H-R-M-A-E-A-N-R-A-F-A-H-F-R-F


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-Q-K-I-R-I-K-L-K-S-Y-D-H-N-L-V-D-K-S-A-E-K-I-V-R-T-V-K-A-T-G-A-I-V-S-G-P-I-P-L-P-T-H-K-R-I-F-T-V-N-R-S-T-F-V-N-K-K-S-R-E-Q-F-E-L-S-S-Y-K-R-L-I-D-I-Y-S-S-T-A-K-T-V-D-A-L-M-K-L-E-L-P-S-G-V-E-V-E-I-K-V


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-L-K-K-G-P-Y-I-N-V-K-L-E-K-R-I-F-A-M-N-E-S-G-K-K-V-V-V-K-T-W-A-R-A-S-M-I-S-P-D-F-V-G-H-T-V-A-V-H-N-G-N-K-F-I-P-V-Y-V-T-E-N-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-R-G-H-A-G-N-K-K-R


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-G-A-R-K-K-I-S-A-E-K-R-K-E-A-L-K-T-M-Y-F-A-K-L-Q-N-V-P-T-S-P-R-K-M-R-L-V-A-D-M-I-R-G-M-E-V-N-R-A-L-G-V-L-K-F-S-S-K-E-A-A-A-R-V-E-K-L-L-R-S-A-I-A-N-W-E-Q-K-N-E-R-K-A-E-S-G-E-L-F-V-T-Q-I-F-V-D-G-G-A-T-L-K-R-M-R-P-A-P-Q-G-R-G-Y-R-I-R-K-R-S-N-H-V-T-L-F-V-G-A-K-S-N-N-E-D-Q-N


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-K-T-K-F-R-R-Q-Q-K-G-R-A-K-G-N-A-Q-R-G-N-Q-L-A-F-G-S-F-G-I-K-A-L-E-T-K-W-I-T-G-R-Q-I-E-A-A-R-I-A-V-T-R-Y-M-Q-R-Q-G-Q-I-W-I-R-I-F-P-D-K-P-I-T-R-K-P-A-D-V-R-M-G-K-G-K-G-A-P-E-G-F-V-A-P-V-T-P-G-R-I-I-I-E-A-E-G-V-S-Y-E-I-A-K-E-A-L-R-L-A-A-Q-K-L-P-I-T-T-K-F-V-V-R-R-D-Y-D-I-Q-N-Q-N-A


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-I-S-L-M-E-A-R-N-L-R-K-E-R-T-G-V-V-L-S-N-K-M-E-K-T-I-T-V-A-A-K-F-K-E-K-H-P-I-Y-G-K-F-V-S-K-T-K-K-Y-H-A-H-D-E-K-N-E-C-N-I-G-D-T-V-R-I-M-E-T-R-P-L-S-K-T-K-R-W-R-L-V-E-I-I-E-R-A-K


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-V-E-S-R-L-T-V-C-D-N-S-G-A-K-E-A-L-C-I-R-V-L-G-G-T-G-R-R-Y-A-S-V-G-D-V-I-V-V-S-V-K-S-V-I-P-S-S-D-V-K-K-G-A-V-S-K-A-L-I-V-R-T-K-K-E-I-R-R-P-D-G-S-Y-I-R-F-D-D-N-A-C-V-L-L-N-N-A-G-E-I-R-G-S-R-I-F-G-P-V-A-R-E-L-R-A-T-N-M-K-V-V-S-L-A-P-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-K-L-H-I-K-K-G-D-T-V-Y-V-N-A-G-E-D-K-G-K-T-G-R-V-L-K-V-L-V-K-E-G-R-A-I-V-E-G-I-N-M-V-S-K-S-T-K-P-N-A-K-N-P-Q-G-G-I-V-K-Q-E-A-S-I-H-I-S-N-L-N-P-V-D-P-K-T-G-K-A-T-R-I-G-R-R-K-S-S-E-G-T-L-V-R-Y-S-K-K-S-G-E-E-I


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-N-T-A-S-L-K-K-E-Y-A-D-R-I-A-P-A-L-K-S-Q-F-Q-Y-S-S-T-M-Q-V-P-V-L-K-K-I-V-I-N-Q-G-L-G-M-A-V-A-D-K-K-I-I-E-V-A-I-N-E-M-T-A-I-T-G-Q-K-A-V-A-T-I-S-R-K-D-I-A-N-F-K-L-R-K-K-M-P-I-G-V-M-V-T-L-R-R-E-R-M-Y-E-F-L-E-K-L-V-R-V-A-L-P-R-I-R-D-F-K-G-I-E-S-K-F-D-G-K-G-N-Y-T-L-G-I-Q-E-Q-I-I-F-P-E-I-N-I-D-S-I-T-R-I-L-G-M-N-I-T-F-V-T-S-A-E-T-D-E-E-G-Y-A-L-L-K-E-F-G-L-P-F-K-N-A-K-K-D


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-E-S-M-K-A-R-E-V-K-R-A-K-L-V-A-R-Y-A-E-K-R-A-A-L-K-Q-I-V-R-T-G-E-P-A-D-A-F-E-A-A-Q-K-L-Q-E-L-P-K-N-S-N-P-I-R-M-H-N-R-C-K-L-T-G-R-P-K-G-Y-I-R-Q-F-G-I-S-R-I-Q-F-R-E-M-A-S-N-G-L-I-P-G-V-K-K-A-S-W


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-D-P-I-A-D-Y-L-T-R-L-R-N-A-I-G-A-K-H-R-V-V-E-V-P-A-S-N-L-K-K-E-I-T-K-I-L-F-E-K-G-Y-I-L-N-Y-K-F-V-E-D-G-P-Q-G-T-I-K-V-A-L-K-Y-D-S-V-N-K-V-N-A-I-K-K-L-E-R-V-S-S-P-G-M-R-K-Y-T-G-Y-K-D-M-P-R-V-I-N-G-L-G-I-A-I-I-S-T-S-K-G-V-M-T-N-K-E-A-A-E-L-K-I-G-G-E-V-L-C-Y-V-Y


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-L-P-I-S-I-P-A-G-V-T-V-T-L-K-D-D-V-V-T-V-K-G-P-K-G-E-L-S-Q-Y-V-N-P-A-I-N-V-A-I-E-D-G-H-V-T-L-T-E-N-E-K-E-M-I-D-N-P-K-Q-K-H-A-F-H-G-L-Y-R-S-L-V-H-N-M-V-V-G-V-S-E-G-Y-K-K-E-L-E-L-V-G-V-G-Y-R-A-S-N-Q-G-N-I-I-E-L-A-L-G-Y-T-H-N-I-F-I-Q-L-P-A-E-V-K-V-E-T-K-S-E-R-N-K-N-P-L-I-I-L-E-S-C-D-K-Q-L-L-G-Q-V-C-S-K-I-R-S-F-R-K-P-E-P-Y-K-G-K-G-I-K-F-V-G-E-V-I-R-R-K-S-G-K-S-A-G-A-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-T-T-K-I-E-R-R-V-K-I-K-Y-R-V-R-N-K-I-S-G-T-A-E-R-P-R-M-S-V-F-R-S-N-K-Q-I-Y-V-Q-I-I-D-D-L-S-G-K-T-L-A-A-A-S-S-L-G-M-A-E-K-V-A-K-K-E-Q-A-A-K-V-G-E-M-I-A-K-K-A-Q-E-A-G-I-T-T-V-V-F-D-R-N-G-Y-L-Y-H-G-R-V-K-E-V-A-D-A-A-R-N-G-G-L-K-F


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-G-V-N-N-R-V-K-V-T-N-D-I-E-L-K-D-R-L-V-A-I-N-R-V-T-K-V-T-K-G-G-R-T-F-S-F-S-A-I-V-V-V-G-N-E-E-G-I-I-G-W-G-L-G-K-A-G-E-V-T-A-A-I-A-K-G-V-E-S-A-K-K-N-L-V-K-V-P-V-L-K-G-T-V-P-H-E-Q-S-A-K-F-G-G-A-E-V-F-I-K-P-A-S-H-G-T-G-V-V-A-G-G-A-M-R-A-V-L-E-S-V-G-I-T-D-V-L-A-K-S-K-G-S-S-N-P-H-N-L-V-K-A-T-I-E-A-L-S-E-M-R-D-A-R-M-I-A-Q-N-R-G-I-S-V-E-K-V-F-R-G


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-N-L-S-N-L-K-P-A-E-G-S-T-K-T-R-K-R-I-G-R-G-A-G-S-G-L-G-G-T-S-T-R-G-H-K-G-A-K-S-R-S-G-Y-S-K-K-V-G-F-E-G-G-Q-M-P-L-Q-R-R-V-P-K-F-G-F-K-N-I-N-R-V-E-Y-K-A-I-N-L-D-T-I-Q-T-L-A-D-A-K-N-L-T-K-V-G-I-S-D-F-I-E-A-G-F-I-S-S-N-Q-L-V-K-V-L-G-N-G-A-L-T-N-K-L-E-V-E-A-N-A-F-S-K-S-A-A-A-A-I-E-A-A-G-G-T-V-V-K-L


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-Q-S-A-I-E-Q-D-G-V-I-V-E-A-L-S-N-A-M-F-R-V-E-L-E-N-G-H-E-I-T-A-H-I-S-G-K-M-R-M-H-Y-I-K-I-L-P-G-D-K-V-R-V-E-M-S-P-Y-D-L-S-K-G-R-I-V-F-R-Y-K


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-I-R-I-V-G-V-D-L-P-Q-N-K-R-G-E-I-A-L-T-Y-V-Y-G-I-G-R-S-S-S-A-K-I-L-D-K-A-G-V-D-K-D-L-K-V-K-D-W-T-D-D-Q-A-A-K-I-R-E-I-I-G-A-E-Y-K-V-E-G-D-L-R-S-E-I-Q-L-N-I-K-R-L-M-D-I-G-C-Y-R-G-V-R-H-R-I-G-L-P-V-R-G-Q-S-T-K-N-N-A-R-T-R-K-G-R-K-K-T-V-A-N-K-K-K-A-T-K


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-K-T-V-A-A-K-K-R-N-V-K-V-D-A-N-G-Q-L-H-V-H-S-S-F-N-N-I-I-V-S-L-A-N-S-E-G-Q-I-I-S-W-S-S-A-G-K-M-G-F-R-G-S-K-K-N-T-P-Y-A-A-Q-M-A-A-Q-D-C-A-K-I-A-F-D-L-G-L-R-K-V-K-A-Y-V-K-G-P-G-N-G-R-E-S-A-I-R-T-I-H-G-A-G-I-E-V-T-E-I-I-D-V-T-P-L-P-H-N-G-C-R-P-P-K-R-R-R-V


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-N-F-P-Q-N-L-K-Y-T-N-E-H-E-W-I-R-V-E-G-D-I-A-Y-V-G-I-T-D-Y-A-Q-E-Q-L-G-D-I-V-F-V-D-I-P-T-V-G-E-T-L-E-A-G-E-T-F-G-T-I-E-V-V-K-T-I-S-D-L-F-L-P-L-A-G-E-I-L-E-Q-N-E-A-L-E-E-N-P-E-L-V-N-K-D-P-Y-G-E-G-W-L-I-K-M-K-P-A-D-A-S-A-A-E-D-L-L-D-A-E-A-Y-K-A-V-V-N-G


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-D-L-I-K-I-A-E-E-A-F-A-T-G-K-Q-H-P-S-F-K-A-G-D-T-V-T-V-A-Y-R-I-I-E-G-N-K-E-R-V-Q-L-Y-R-G-V-V-I-K-I-A-G-H-G-D-K-K-R-F-T-V-R-K-M-S-G-T-V-G-V-E-R-I-F-P-I-E-S-P-A-I-D-S-I-E-V-N-K-V-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-T-G-K-K-A-R-I-K-E-K-R-V-N-N


### FUNCTION Part of the high-affinity ATP-driven potassium transport  system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-K-T-L-F-K-S-L-K-I-T-L-V-F-C-V-F-F-S-V-F-Y-I-L-I-L-W-L-F-A-Q-V-A-G-P-N-K-G-N-A-E-V-A-T-L-D-G-K-V-V-G-A-A-N-V-G-Q-M-F-T-K-D-I-Y-F-W-G-R-P-S-C-A-G-D-G-Y-D-A-S-S-S-S-G-S-N-K-G-P-T-N-P-E-Y-L-A-E-V-E-A-R-I-D-T-F-L-V-H-H-P-Y-L-S-R-K-D-V-P-A-E-M-V-T-A-S-A-S-G-L-D-P-N-I-T-P-Q-C-A-Y-V-Q-V-K-R-V-A-Q-A-R-G-L-T-E-N-Q-V-K-E-I-V-D-Q-S-V-E-K-P-L-L-G-I-F-G-T-E-K-I-N-V-L-K-L-N-I-A-L-E-E-N-K


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-V-D-V-K-T-C-L-D-N-A-Q-E-K-M-D-M-A-V-M-Y-L-E-E-A-L-A-H-I-R-A-G-K-A-S-T-R-L-L-D-G-I-R-V-D-S-Y-G-S-M-V-P-I-S-N-V-A-A-L-S-T-P-D-A-R-S-I-T-I-K-P-W-D-K-S-M-F-R-A-I-E-K-A-I-I-D-S-D-L-G-I-M-P-E-N-N-G-E-V-I-R-I-G-I-P-P-L-T-E-E-R-R-R-Q-L-A-K-Q-C-K-A-E-G-E-T-A-K-V-S-V-R-N-A-R-R-D-G-I-D-A-L-K-K-A-V-K-D-G-L-A-E-D-E-Q-K-N-A-E-A-K-L-Q-K-I-H-D-K-Y-I-K-Q-I-E-D-M-L-A-D-K-D-K-E-I-M-T-V


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-N-Q-Y-E-T-V-F-I-L-T-P-V-L-S-D-V-Q-M-K-E-A-V-E-K-F-K-G-I-L-Q-A-E-G-A-E-I-I-N-E-E-N-W-G-L-K-K-L-A-Y-P-I-Q-K-K-S-T-G-F-Y-Q-L-V-E-F-N-A-D-P-T-V-I-D-K-L-E-L-N-F-R-R-D-E-R-V-I-R-F-L-T-F-K-M-D-K-Y-A-A-E-Y-A-A-K-R-R-S-V-K-S-N-K-K-E-D


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Q-Q-T-Q-S-E-I-R-Y-L-T-P-P-S-V-D-V-K-K-K-K-Y-C-R-F-K-K-S-G-I-R-Y-I-D-Y-K-D-P-E-F-L-K-K-F-L-N-E-Q-G-K-I-L-P-R-R-I-T-G-T-S-L-K-F-Q-R-R-I-A-Q-A-V-K-R-A-R-H-L-A-L-L-P-Y-V-T-D-M-M-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-I-I-L-K-E-D-I-V-N-L-G-Y-K-N-D-I-V-N-V-K-S-G-Y-G-R-N-Y-L-I-P-T-G-K-A-I-I-A-S-P-S-A-K-K-M-L-A-E-D-L-K-Q-R-A-H-K-L-E-K-I-K-K-D-A-E-A-L-A-A-K-L-E-G-V-S-L-T-I-A-T-K-V-S-S-T-G-T-I-F-G-S-V-S-N-I-Q-I-A-E-A-L-A-K-L-G-H-E-I-D-R-K-I-I-V-V-K-D-A-V-K-E-V-G-N-Y-K-A-I-V-K-L-H-K-E-V-S-V-E-I-P-F-E-V-V-A-E


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-I-K-K-E-E-V-Y-K-I-G-L-F-N-K-P-H-G-I-H-G-E-L-Q-F-T-F-T-D-D-I-F-D-R-V-D-C-D-Y-L-I-C-L-L-D-G-I-F-V-P-F-F-I-E-E-Y-R-F-R-S-D-S-T-A-L-V-K-L-E-G-I-D-T-A-E-R-A-R-M-F-T-N-V-E-V-Y-F-P-V-K-H-A-E-E-A-E-D-G-E-L-S-W-N-F-F-V-G-F-R-M-E-D-V-R-H-G-E-L-G-E-V-V-E-V-D-T-A-T-V-N-T-L-F-V-V-E-Q-E-D-G-E-E-L-L-V-P-A-Q-E-E-F-I-V-E-I-N-Q-E-K-K-L-I-T-V-E-L-P-E-G-L-L-N-L-E-D-L-E-E-D


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-K-T-T-L-L-V-V-G-R-T-V-E-Q-H-Y-I-T-A-I-N-D-Y-I-Q-R-T-K-R-F-I-T-F-D-M-E-V-I-P-E-L-K-N-T-K-S-L-S-M-D-Q-Q-K-E-K-E-G-E-L-I-L-K-A-L-Q-P-G-D-V-I-V-L-L-D-E-H-G-K-E-M-R-S-L-E-F-A-D-Y-M-K-R-K-M-N-T-V-N-K-R-L-V-F-V-I-G-G-P-Y-G-F-S-E-K-V-Y-Q-V-A-N-E-K-I-S-M-S-K-M-T-F-S-H-Q-M-I-R-L-I-F-V-E-Q-I-Y-R-A-M-T-I-L-N-G-G-P-Y-H-H-E


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-D-P-K-E-K-E-K-M-A-E-E-L-N-V-E-E-T-K-D-T-A-E-E-Q-P-Q-D-D-Q-A-E-E-A-A-P-L-T-H-E-E-Q-L-E-K-E-L-E-D-A-Q-A-V-I-E-E-Q-K-D-K-Y-L-R-L-S-A-E-F-D-N-Y-R-K-R-T-M-K-E-K-A-E-L-I-L-N-G-G-E-K-S-I-S-S-I-L-P-V-I-D-D-F-E-R-A-I-K-T-M-E-T-A-K-D-V-K-A-V-K-E-G-V-E-L-I-Y-N-K-F-M-A-V-M-A-Q-N-G-V-K-V-I-E-T-K-D-Q-P-L-D-T-D-Y-H-E-A-I-A-V-I-P-A-P-S-E-E-Q-K-G-K-I-L-D-C-V-Q-T-G-Y-T-L-N-D-K-V-I-R-H-A-K-V-V-V-G-E


### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-S-E-N-K-Q-A-L-Q-V-A-A-L-K-N-G-T-V-I-D-H-I-P-S-E-K-L-F-T-V-V-Q-L-L-G-V-E-Q-M-K-C-N-I-T-I-G-F-N-L-D-S-K-K-L-G-K-K-G-I-I-K-I-A-D-K-F-F-C-D-E-E-I-N-R-I-S-V-V-A-P-Y-V-K-L-N-I-I-R-D-Y-E-V-V-E-K-K-E-V-R-M-P-D-E-L-H-G-I-V-K-C-A-N-P-K-C-I-T-N-N-E-P-M-P-T-L-F-H-V-I-D-K-D-N-C-I-V-K-C-H-Y-C-E-K-E-Q-K-R-E-E-I-T-I-L


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-E-V-G-V-L-S-M-R-Y-A-K-A-M-I-E-Y-A-Q-E-K-G-V-E-D-R-L-Y-N-E-F-F-T-L-S-H-S-F-R-V-Q-P-G-L-R-E-V-L-D-N-P-V-V-S-V-K-D-K-L-A-L-I-C-T-A-A-D-G-N-G-E-S-S-R-E-F-V-R-F-I-T-L-V-L-R-N-R-R-E-G-Y-L-Q-F-I-S-L-M-Y-L-D-L-Y-R-K-L-K-H-I-G-V-G-K-L-I-T-A-V-P-V-D-K-E-T-E-N-R-I-R-S-A-A-A-H-I-L-H-A-Q-M-E-L-D-T-V-I-D-P-S-I-E-G-G-F-I-F-D-I-N-D-Y-R-L-D-A-S-I-A-T-Q-L-K-R-V-K-Q-Q-F-I-D-K-N-R-R-I-V


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-L-L-L-P-D-S-G-L-L-F-W-M-F-V-A-F-G-V-V-F-V-I-L-A-K-Y-G-F-P-I-I-I-K-M-V-E-G-R-K-T-Y-I-D-Q-S-L-E-V-A-R-E-A-N-A-Q-L-A-H-L-K-E-E-G-E-A-L-V-A-A-A-N-K-E-Q-G-R-I-L-K-E-A-M-E-E-R-D-K-I-V-H-E-A-R-K-Q-A-E-I-A-A-Q-K-E-L-D-A-V-K-Q-Q-I-Q-I-E-K-D-E-A-I-R-D-I-R-R-Q-V-A-V-L-S-V-D-I-A-E-K-V-L-R-K-N-L-Q-D-K-E-S-Q-M-G-M-I-D-R-M-L-D-E-V-L-T-P-N-K-N


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-S-V-N-H-V-A-S-K-A-R-R-K-K-I-L-K-L-T-R-G-Y-F-G-A-R-K-N-V-W-T-V-A-K-N-T-W-E-K-G-L-T-Y-A-F-R-D-R-R-N-K-K-R-N-F-R-A-L-W-I-Q-R-I-N-A-A-A-R-L-E-G-M-S-Y-S-K-L-M-G-G-L-H-K-A-G-I-E-I-N-R-K-V-L-A-D-L-A-M-N-H-P-E-A-F-K-A-V-V-A-K-A-K-A-A


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-N-D-T-L-K-G-Q-Y-R-I-N-E-Q-I-R-A-K-E-V-R-I-V-G-D-E-I-E-P-K-V-Y-P-I-F-Q-A-L-K-M-A-E-E-K-E-L-D-L-V-E-I-S-P-N-A-Q-P-P-V-C-R-I-I-D-Y-S-K-F-L-Y-Q-L-K-K-R-Q-K-E-Q-K-A-K-Q-V-K-V-N-V-K-E-I-R-F-G-P-Q-T-D-D-H-D-Y-N-F-K-L-K-H-A-R-G-F-L-E-D-G-D-K-V-K-A-Y-V-F-F-K-G-R-S-I-L-F-K-E-Q-G-E-V-L-L-L-R-F-A-N-D-L-E-D-F-A-K-V-D-Q-M-P-V-L-E-G-K-R-M-T-I-Q-L-S-P-K-K-R-K-C-L-K-N-R-R-L-P-N-R


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-R-I-V-A-I-D-Y-G-R-K-R-T-G-I-A-V-S-D-T-L-Q-L-I-A-N-G-L-T-T-V-P-T-H-E-L-L-N-F-I-G-G-Y-V-A-K-E-P-V-E-R-I-I-I-G-L-P-K-Q-M-N-N-E-A-S-E-N-M-K-N-I-E-P-F-V-R-S-L-K-K-R-F-P-E-L-P-V-E-Y-V-D-E-R-F-T-S-V-L-A-H-R-T-M-L-E-A-G-L-K-K-K-D-R-Q-N-K-A-L-V-D-E-I-S-A-T-I-I-L-Q-T-Y-L-E-S-K-R-F


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-Q-P-S-V-N-I-K-N-K-R-A-T-F-D-Y-E-L-M-D-T-Y-T-A-G-I-V-L-T-G-T-E-I-K-S-I-R-L-G-K-A-S-L-V-D-T-F-C-Y-F-A-K-G-E-L-W-V-K-N-M-H-I-A-E-Y-F-Y-G-S-Y-N-N-H-T-A-R-R-D-R-K-L-L-L-N-K-K-E-L-E-K-I-Q-R-G-M-K-D-P-G-F-T-T-V-P-V-R-L-F-I-N-E-K-G-L-A-K-L-V-V-A-L-A-K-G-K-K-Q-Y-D-K-R-E-S-I-K-E-K-D-D-R-R-D-M-A-R-M-F-K-R


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-V-P-C-R-L-R-P-F-L-W-N-S-P-K-V-A-V-K-R-I-P-R-Q-C-I-E-G-I-V-V-S-T-K-M-Q-K-T-V-V-I-E-V-E-R-T-K-K-H-P-K-Y-G-K-T-V-Q-Y-T-K-K-Y-K-I-H-D-P-L-E-E-C-S-V-G-D-R-V-L-A-H-E-T-R-H-F-S-K-T-K-Y-F-R-F-Y-R-K-L-Y


### FUNCTION Escorts unspliced or incompletely spliced viral pre-mRNAs ### SEQUENCE -M-A-G-R-E-E-D-A-N-L-L-Y-T-V-R-I-I-K-I-L-Y-D-S-N-P-Y-P-S-G-A-G-S-R-T-A-R-R-N-R-R-R-R-W-R-Q-R-Q-H-Q-V-D-A-L-A-S-R-I-L-Q-Y-R-L-G-G-P-Q-E-P-P-H-L-D-I-P-D-L-S-K-L-H-L-D-P-L-D-Q-P-A-S-T-E-T-G-D-N-Q-L-G-T-Q-P-S-N-S-A


### FUNCTION Nuclear transcriptional activator of viral gene expression, that is essential for viral transcription from the LTR promoter and replication Acts as a sequence-specific molecular adapter, directing components of the cellular transcription machinery to the viral RNA to promote processive transcription elongation by the RNA polymerase II ### SEQUENCE -M-N-P-I-D-P-Q-V-A-P-W-E-H-P-G-A-A-P-E-T-P-C-T-N-C-Y-C-K-K-C-C-F-H-C-P-V-C-F-T-K-K-A-L-G-I-S-Y-G-R-K-R-R-G-R-K-S-A-V-H-S-T-N-N-Q-D-P-V-R-Q-Q-S-L-P-K-R-S-R-I-Q-N-S-Q-E-E-S-Q-E-E-V-E-A-E-T-T-S-G-G-R-P-R-Q-Q-D-S-S-V-S-S-G-R-T-S-G-T-S-S-S-G-Y-T-R-P-F-K-T-S-S-G-S-S-G-S-A-C-K-H


### FUNCTION Stimulates gene expression driven by the HIV-2 LTR Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle Cell cycle arrest creates a favorable environment for maximizing viral expression and production ### SEQUENCE -M-E-Q-A-P-N-D-N-G-P-Q-R-E-P-Y-T-E-W-L-L-D-I-L-E-E-I-K-Q-E-A-V-K-H-F-P-R-P-I-L-Q-G-V-G-N-W-V-F-T-I-Y-G-D-S-W-E-G-V-Q-E-L-I-K-I-L-Q-R-A-L-F-T-H-Y-R-H-G-C-I-H-S-R-I-G-S


### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-D-G-F-G-S-D-F-S-V-G-G-S-S-S-G-K-V-D-T-G-A-I-M-E-Q-V-K-V-Q-I-A-V-A-N-A-Q-E-L-L-Q-R-M-T-D-K-C-F-R-K-C-I-G-K-P-G-G-S-L-D-N-S-E-Q-K-C-V-A-M-C-M-D-R-Y-M-D-A-W-N-I-V-S-R-A-Y-N-S-R-L-Q-R-E-R-A-K-M


### FUNCTION Probable regulator of exocrine pancreas development ### SEQUENCE -M-A-A-I-P-S-S-G-S-L-V-A-T-H-D-Y-Y-R-R-R-L-G-S-T-S-S-S-S-S-C-G-S-V-D-Y-S-G-E-V-I-P-H-H-P-G-L-P-K-A-D-P-G-H-W-W-A-S-F-F-F-G-K-S-T-H-P-V-M-T-T-V-S-E-S-P-E-N-S-G-S-F-R-I-T-N-G-L-V-P-C-G-L-T-Q-E-S-V-Q-K-Q-K-V-S-D-S-K-S-N-S-S-P-S-A


### FUNCTION Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability Required for efficient homologous recombination-dependent repair of double-strand breaks ### SEQUENCE -M-D-P-G-S-T-A-S-P-L-Q-C-T-A-G-F-P-S-K-N-R-V-A-I-L-A-E-L-D-K-E-K-R-K-L-L-L-Q-N-Q-S-S-T-N-N-P-G-A-S-I-A-L-A-R-P-N-M-N-K-D-F-R-D-H-S-E-Q-Q-H-I-A-A-Q-Q-K-A-A-L-Q-H-A-H-A-H-S-S-G-Y-F-I-T-Q-D-S-A-F-G-N-L-I-L-P-V-I-P-R-L-E-A-E


### FUNCTION Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the tom40 translocation pore ### SEQUENCE -M-V-A-V-G-K-T-S-A-I-A-A-G-V-C-G-A-L-L-L-G-Y-C-I-Y-F-D-R-K-R-R-S-D-P-N-F-K-N-R-L-R-E-K-R-R-K-Q-K-I-A-K-E-R-A-G-Q-S-R-L-P-D-L-K-D-A-E-A-V-Q-K-F-F-L-E-E-I-Q-L-G-E-E-L-L-A-Q-G-D-F-E-K-G-V-D-H-L-T-N-A-I-A-I-C-G-Q-P-Q-Q-L-L-Q-V-L-Q-Q-T-L-P-P-P-V-F-Q-M-L-L-T-K-L-P-T-I-S-Q-R-I-G-N-A-Q-N-L-S-E-D-D-V-E


### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-D-C-A-K-T-G-A-C-N-C-G-A-T-C-K-C-T-N-C-Q-C-K-T-C-K-K-S-C-C-P-C-C-P-S-G-C-S-K-C-A-S-G-C-V-C-K-D-N-S-C-G-S-S-C-C-Q


### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-D-C-A-K-T-G-P-C-N-C-G-A-T-C-K-C-T-N-C-Q-C-T-T-C-K-K-S-C-C-S-C-C-P-S-G-C-S-K-C-A-S-G-C-V-C-K-G-N-S-C-G-S-S-C-C-Q


### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-R-A-L-I-L-L-S-L-G-L-L-R-V-A-V-P-S-P-P-Q-V-V-V-Y-T-Y-K-P-V-V-H-G-E-K-N-T-L-L-C-H-A-K-E-F-N-P-P-N-V-E-L-Q-L-F-E-D-G-N-V-F-S-Q-A-N-Q-T-D-L-S-F-E-S-N-W-K-F-K-L-T-K-F-I-E-L-I-P-R-E-D-V-E-Y-S-C-H-V-M-Y-M-G-K-T-S-I-Y-K-L-E-S-F


### FUNCTION Beta-bungarotoxin is a presynaptic neurotoxin of the venom The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and is non-toxic ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-W-A-E-L-T-P-V-S-S-R-K-R-H-P-D-C-D-K-P-P-D-T-R-I-C-Q-T-V-V-R-A-F-Y-Y-K-P-S-E-K-R-C-V-Q-F-R-Y-G-G-C-K-G-N-G-N-H-F-K-S-D-H-L-C-R-C-E-C-L-E-Y-R


### FUNCTION Beta-bungarotoxin is a presynaptic neurotoxin of the venom The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and is non-toxic ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-W-A-E-L-T-P-V-S-S-R-K-R-H-P-D-C-D-K-P-P-D-T-K-I-C-Q-T-V-V-R-A-F-Y-Y-K-P-S-A-K-R-C-V-Q-F-R-Y-G-G-C-N-G-N-G-N-H-F-K-S-D-H-L-C-R-C-E-C-L-E-Y-P


### FUNCTION Beta-bungarotoxin is a presynaptic neurotoxin of the venom The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and is non-toxic ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-C-A-E-L-T-P-V-S-S-R-Q-R-H-R-D-C-D-K-P-P-D-K-G-N-C-G-S-V-R-R-A-F-Y-Y-D-T-R-L-K-T-C-K-A-F-P-Y-R-G-C-N-G-N-G-N-H-F-K-T-E-T-L-C-R-C-E-C-L-V-Y-P


### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-T-C-L-I-C-P-E-K-D-C-Q-K-V-H-T-C-R-N-E-E-K-I-C-V-K-R-F-Y-D-K-N-Q-L-G-W-R-A-Q-R-G-C-A-V-S-C-P-K-A-K-P-N-E-T-V-Q-C-C-S-T-D-D-C-N-R


### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-A-I-V-C-L-D-L-G-Y-T-L-T-C-L-I-C-P-E-K-D-C-Q-K-V-H-T-C-R-N-E-E-K-I-C-V-K-R-S-Y-D-K-N-Q-L-G-W-R-A-Q-R-G-C-A-V-S-C-P-K-A-K-P-N-E-T-V-Q-C-C-S-T-D-K-C-N-K


### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-A-I-V-C-L-D-L-G-Y-T-L-T-C-L-I-C-P-E-K-D-C-Q-K-V-H-T-C-R-N-E-E-K-I-C-V-K-R-F-Y-D-K-N-Q-L-G-W-R-A-Q-R-G-C-A-V-S-C-P-K-A-K-P-N-E-T-V-Q-C-C-S-T-D-K-C-N-K


### FUNCTION Postsynaptic neurotoxin that binds and inhibits neuronal nicotinic acetylcholine receptors  Is a selective, and slowly reversible antagonist of alpha-3/CHRNA3-containing and some alpha-4/CHRNA4-containing AChRs ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-T-C-L-I-S-P-S-S-T-P-Q-T-C-P-Q-G-Q-G-I-C-F-L-K-A-Q-C-D-K-F-C-S-I-R-G-P-V-I-E-Q-G-C-V-A-T-C-P-Q-F-R-S-N-Y-R-S-L-L-C-C-T-T-D-N-C-N-H


### FUNCTION Postsynaptic neurotoxin that binds and inhibits neuronal nicotinic acetylcholine receptors  Is a selective, and slowly reversible antagonist of alpha-3/CHRNA3-containing and some alpha-4/CHRNA4-containing AChRs ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-T-C-L-I-S-P-S-S-T-P-Q-T-C-P-Q-G-Q-D-I-C-F-L-K-A-Q-C-D-K-F-C-S-I-R-G-P-V-I-E-Q-G-C-V-A-T-C-P-Q-F-R-S-N-Y-R-S-L-L-C-C-T-T-D-N-C-N-H


### FUNCTION May be involved in the cellular control mechanism of the secretion of toxins from the gland into the venom ### SEQUENCE -M-A-A-T-L-T-P-E-Q-I-T-E-Y-K-G-I-F-E-M-F-D-E-E-G-N-G-L-V-K-T-D-D-L-E-S-L-M-S-L-V-G-I-N-P-T-K-R-D-L-A-N-M-A-K-D-V-D-K-D-K-K-G-T-F-N-C-D-G-F-L-A-L-M-G-I-Y-H-E-K-S-K-N-Q-D-E-E-L-R-A-A-F-K-V-F-D-K-E-H-K-G-Y-I-E-W-D-T-L-K-Y-V-L-M-N-A-G-E-P-L-N-E-Q-E-A-E-L-M-M-K-E-A-D-K-D-G-D-G-T-I-D-Y-E-E-F-V-A-M-M-T-G-E-S-F-K-L-T-Q


### FUNCTION Component of the class I major histocompatibility complex ### SEQUENCE -M-G-L-L-I-C-S-L-L-L-G-L-L-C-C-S-M-A-K-D-T-P-P-K-V-E-V-Y-T-R-E-P-E-E-F-G-K-P-N-S-F-I-C-H-V-S-G-F-Y-P-P-Q-I-N-I-T-L-L-K-D-G-K-E-I-P-N-T-Q-Q-T-D-L-A-F-E-A-N-W-Y-Y-Y-L-T-K-H-V-S-F-T-P-K-E-D-D-E-F-I-C-R-V-T-H-M-G-K-S-K-D-H-F-L-M-I-G-L


### FUNCTION May play a role in the regulation of cellular reactive oxygen species metabolism May participate in cell growth regulation ### SEQUENCE -M-S-T-N-N-C-T-F-K-D-R-C-V-S-I-L-C-C-K-F-C-K-Q-V-L-S-S-R-G-M-K-A-V-L-L-A-D-T-D-I-D-L-F-S-T-D-I-P-P-T-N-T-V-D-F-I-G-R-C-Y-F-T-G-I-C-K-C-K-L-K-D-I-A-C-L-K-C-G-N-I-V-G-Y-H-V-I-V-P-C-S-S-C-L-L-S-C-N-N-G-H-F-W-M-F-H-S-Q-A-V-Y-G-I-N-R-L-D-A-T-G-V-N-L-L-L-W-G-N-L-P-E-T-E-E-C-T-D-E-E-T-L-E-I-S-A-E-E-Y-I-R


### FUNCTION May modulate activity of cullin-RING E3 ubiquitin ligase  complexes Associates with the NF-kappa-B complex and suppresses its transcriptional activity ### SEQUENCE -M-G-R-L-H-C-T-Q-D-P-V-P-E-A-V-R-G-D-M-Q-Q-L-N-Q-L-G-A-Q-Q-F-S-D-L-T-E-V-L-F-H-F-L-T-E-P-K-E-V-E-R-F-L-A-Q-L-S-E-F-A-T-S-N-Q-I-S-L-G-P-L-K-S-I-M-K-S-L-L-L-V-P-N-G-A-L-K-K-G-L-T-A-E-Q-V-R-T-D-L-Q-T-L-G-L-S-E-E-K-A-T-Y-F-S-E-K-W-K-Q-N-A-S-T-L-A-Q-W-A-M-G-Q-T-L-M-V-N-Q-L-I-D-M-E-W-R-F-G-V-T-S-G-S-S-E-L-E-K-V-G-S-I-F-L-Q-L-K-L-V-V-K-K-G-K-Q-T-E-N-L-Y-M-E-L-T-L-P-Q-F-Y-S-F-L-H-E-M-E-R-V-R-A-S-M-E-C-L-S


### FUNCTION May play a role in ciliary assembly ### SEQUENCE -M-A-S-L-F-T-Q-E-I-H-L-S-K-R-H-E-E-I-L-S-Q-R-L-M-L-L-Q-K-M-K-N-K-F-G-D-E-N-T-E-R-A-S-L-L-Q-A-T-E-T-A-S-R-R-N-L-R-L-L-K-D-I-D-A-A-E-E-A-F-Q-T-K-L-I-P-H-P-Q-P-S-M-L-S-L-E-T-R-Y-W-A-S-V-E-E-H-I-P-K-W-E-L-F-L-L-G-R-A-P-Y-P-I-G-A-E-N-Q-N-E-V-P-F-V-Q-T-E-A-K-L


### FUNCTION May play a role in TRPCs intracellular trafficking ### SEQUENCE -M-S-S-D-F-P-H-Y-N-F-R-M-P-N-I-G-F-Q-N-L-P-L-N-I-Y-I-V-V-F-G-T-A-V-F-V-F-I-L-S-L-L-F-C-C-Y-L-I-R-L-R-H-Q-A-H-K-E-F-Y-A-Y-K-Q-V-I-L-K-E-K-V-K-E-L-N-L-H-E-L-C-A-V-C-L-E-D-F-K-P-R-D-E-L-G-I-C-P-C-K-H-A-F-H-R-K-C-L-V-K-W-L-E-V-R-K-V-C-P-L-C-N-M-P-V-L-Q-L-A-Q-L-H-S-K-Q-D-R-G-P-P-Q-E-P-L-P-G-A-E-N-I-V


### FUNCTION Regulates drug efflux through modulation of ABCB1 localization and activity ### SEQUENCE -M-T-V-G-A-R-L-R-S-K-A-A-S-S-L-V-G-R-R-P-L-G-R-S-R-R-A-G-D-E-E-T-D-A-I-V-E-H-L-E-G-E-D-E-D-P-A-S-P-D-C-E-R-E-E-G-G-R-R-A-G-T-P-S-A-R-R-V-H-L-A-A-L-P-E-R-Y-D-S-L-E-E-P-A-P-G-D-K-P-K-K-R-Y-R-R-K-L-K-K-Y-G-K-N-F-G-K-A-I-S-K-G-C-R-Y-I-V-I-G-L-Q-G-F-A-A-A-Y-S-A-P-F-G-V-A-T-S-V-V-S-F-V-R


### FUNCTION Has antibacterial activity ### SEQUENCE -M-P-V-T-K-S-Y-F-M-T-V-V-V-V-L-I-L-V-D-E-T-T-G-G-L-F-G-F-R-S-S-K-R-Q-E-P-W-I-A-C-E-L-Y-Q-G-L-C-R-N-A-C-Q-K-Y-E-I-Q-Y-L-S-C-P-K-T-R-K-C-C-L-K-Y-P-R-K-I-T-S-F


### FUNCTION Core component of the MITRAC  complex, that regulates cytochrome c oxidase assembly Requires for coordination of the early steps of cytochrome c oxidase assembly with the synthesis of MT-CO1 ### SEQUENCE -M-P-S-A-K-Q-L-A-D-I-G-Y-K-T-F-S-A-S-M-M-L-L-T-V-Y-G-G-Y-L-C-S-V-R-A-Y-R-Y-L-Q-L-R-S-A-R-R-Q-A-A-E-E-Q-K-T-S-G-V-L


### FUNCTION Antibacterial protein ### SEQUENCE -M-K-P-S-S-L-L-L-F-T-T-T-I-L-L-C-L-S-M-A-Q-P-R-A-T-R-K-G-V-T-P-K-Q-G-Y-C-P-E-F-L-L-D-C-P-F-V-L-L-P-V-C-S-R-D-K-G-C-K-G-T-K-K-C-C-F-Y-Y-C-Q-M-R-C-V-E-P-W-T-T-L-T


### FUNCTION Plays a role in mitochondrial morphogenesis ### SEQUENCE -M-A-A-W-G-R-R-R-L-G-P-G-G-G-G-S-R-E-R-V-S-L-S-A-T-D-C-Y-I-V-H-E-I-Y-S-G-E-N-A-Q-D-Q-F-E-Y-E-L-E-Q-A-L-E-A-Q-Y-K-Y-I-V-I-E-P-T-R-I-G-D-E-T-A-R-W-I-T-V-G-N-C-L-H-K-T-A-V-L-A-G-T-A-C-L-F-T-P-L-A-L-P-L-D-Y-S-H-Y-I-S-L-P-A-G-V-L-S-L-A-C-C-T-L-Y-G-I-S-W-Q-F-D-P-C-C-K-Y-Q-V-E-Y-D-A-Y-K-L-S-R-L-P-L-H-T-L-T-S-S-T-P-V-V-L-V-R-K-D-D-L-H-R-K-R-L-H-N-T-I-A-L-A-A-L-V-Y-C-V-K-K-V-Y-E-L-Y-A-V


### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase  to ubiquinol Promotes maturation of the iron-sulfur protein subunit Sdhb of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants May act together with SDHAF1 ### SEQUENCE -M-P-G-K-H-V-S-R-V-R-A-L-Y-R-R-I-L-L-L-H-R-A-L-P-P-D-L-K-A-L-G-D-Q-Y-V-K-D-E-F-R-R-H-K-T-V-G-P-G-E-A-Q-R-F-L-K-E-W-E-T-Y-A-A-V-L-W-Q-Q-A-E-D-S-R-Q-S-S-T-G-K-A-C-F-G-T-S-L-P-E-E-K-L-N-D-F-R-D-E-Q-I-G-Q-L-Q-E-L-M-Q-E-A-T-K-P-N-R-Q-F-S-I-T-E-S-T-K-P-Q-L


### FUNCTION Putative COX assembly factor ### SEQUENCE -M-S-T-S-V-P-Q-G-H-N-W-T-R-P-V-K-K-D-D-D-E-E-D-P-L-D-Q-L-I-T-R-S-G-C-A-A-S-H-F-A-V-Q-E-C-M-A-Q-H-Q-D-W-R-Q-C-Q-P-Q-V-Q-A-F-R-D-C-M-S-A-Q-Q-A-R-R-R-E-E-L-Q-R-R-K-E-Q-A-S-A-Q-H


### FUNCTION May play a role in BANF1 regulation and influence tissue-specific roles of BANF1 ### SEQUENCE -M-D-D-M-S-P-R-L-R-A-F-L-S-E-P-I-G-E-K-D-V-A-W-V-D-G-I-S-R-E-L-A-I-N-L-V-T-K-G-F-N-K-A-Y-V-L-L-G-Q-F-L-L-M-H-K-N-E-A-E-F-Q-R-W-I-I-C-C-C-G-A-T-E-C-E-A-R-Q-S-S-T-C-L-K-E-W-C-S-C-F-L


### FUNCTION May modulate activity of cullin-RING E3 ubiquitin ligase  complexes May down-regulate activation of NF-kappa-B ### SEQUENCE -M-L-L-D-L-S-E-E-H-K-E-H-L-A-F-L-P-Q-V-D-T-A-V-V-A-E-F-G-R-I-A-V-E-F-L-R-R-G-S-N-P-K-I-Y-E-G-A-A-R-K-L-N-V-S-S-D-T-I-Q-H-G-V-E-G-L-T-Y-L-L-T-E-S-S-K-L-M-I-S-E-L-D-F-Q-D-S-V-F-V-L-G-F-S-E-E-L-N-K-L-L-L-Q-L-Y-L-D-N-R-K-E-I-R-T-I-L-N-E-L-A-P-R-L-P-S-Y-H-S-L-E-W-R-L-D-V-Q-L-A-S-R-S-L-R-Q-Q-I-K-P-A-V-T-I-K-L-H-L-D-Q-N-G-D-H-S-T-H-F-L-Q-T-D-P-A-T-L-L-H-L-V-Q-Q-L-E-Q-A-L-E-E-M-K-T-N-H-C-R-R-V-V-R-S-I-K


### FUNCTION May be involved in 20S pre-rRNA processing ### SEQUENCE -M-A-G-A-A-E-D-V-R-V-L-F-G-A-A-V-R-A-A-L-E-A-W-P-A-L-Q-I-A-V-E-N-G-F-G-G-V-H-S-Q-E-K-A-E-W-L-G-G-A-V-E-D-Y-F-I-A-N-A-D-L-E-L-E-E-I-E-D-F-L-G-E-L-M-T-T-E-F-D-T-V-V-E-D-G-S-L-P-Q-V-S-Q-Q-L-Q-T-M-F-H-H-F-Q-K-G-D-G-A-A-L-Q-E-M-T-S-Q-I-N-Q-K-K-C-K-V-T-A-T-P-L-M-T-A-K-E-T-D-V-A-E-D-D-V-D-S-V-E-E-M-E-V-T-A-T-N-D-G-A-T-T-D-E-V-C-P-Q-P-Q-P-S-D-P-D-T-Q-T-I-K-E-E-D-I-V-E-D-G-W-T-I-V-R-R-K-K


### FUNCTION Single strand-specific metallo-endoribonuclease involved in rRNA maturation ### SEQUENCE -M-S-L-V-I-K-N-L-Q-R-V-V-P-I-R-R-V-P-L-R-R-K-M-D-L-V-R-S-I-L-G-V-K-K-F-D-L-G-I-I-C-V-D-N-K-T-I-Q-N-I-N-R-I-Y-R-N-K-N-V-P-T-D-V-L-S-F-S-F-H-E-N-L-K-A-G-E-F-P-Q-P-H-S-P-D-D-Y-N-L-G-D-I-F-L-G-V-E-Y-I-L-Q-H-C-R-E-S-E-D-Y-C-D-V-L-T-V-T-A-T-H-G-L-C-H-L-L-G-F-T-H-S-S-K-A-E-W-Q-K-M-Y-N-Q-E-K-L-V-L-E-E-L-S-R-Y-T-G-A-R-L-Q-P-L-S-R-G-L-Y