### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-Q-Q-W-L-E-I-G-K-V-V-A-A-Q-G-L-R-G-E-V-R-V-Q-P-A-T-D-F-A-E-R-L-T-R-P-G-A-R-L-V-G-R-S-L-D-D-G-R-V-F-R-L-Q-S-G-R-A-I-P-G-K-D-L-F-V-C-R-F-E-G-V-E-E-R-N-A-A-E-K-L-V-G-S-T-L-W-I-G-A-A-E-R-P-V-L-A-A-G-E-F-W-L-P-D-L-M-G-V-R-V-F-R-Q-D-T-G-E-A-I-G-E-V-S-D-M-T-R-A-G-N-D-L-L-V-I-R-L-S-G-G-K-T-V-M-V-P-F-V-H-A-L-V-P-V-V-D-L-E-A-G-R-I-E-V-V-A-I-P-G-L-L-D-P-E-A-A-E-A-D-E-A


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-G-E-K-T-R-K-I-L-V-D-N-R-K-A-R-F-E-Y-E-I-L-E-T-Y-S-A-G-L-A-L-L-G-T-E-V-K-A-I-R-A-G-R-A-N-L-N-D-A-F-A-R-I-H-H-G-E-V-L-L-Y-N-M-N-I-S-P-L-Q-T-A-G-A-F-A-H-D-P-L-R-T-R-K-L-L-L-K-R-R-E-I-H-K-L-T-G-R-V-E-E-K-G-L-T-L-I-P-L-K-L-Y-L-E-G-S-W-V-K-L-D-L-G-L-A-R-G-K-K-L-Y-D-K-R-E-D-I-K-K-R-E-T-K-R-D-I-E-R-A-M-R-R


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-R-I-K-L-V-A-V-G-R-L-R-E-E-A-Y-E-R-A-C-A-E-Y-A-R-R-L-A-A-Y-A-R-L-E-L-V-E-V-R-D-A-R-I-A-D-S-R-A-G-L-L-K-E-G-Q-A-L-L-D-Q-L-H-P-G-E-H-A-V-L-L-D-S-G-G-K-Q-F-T-S-V-E-L-A-D-W-L-E-N-H-T-V-Q-E-P-V-F-I-V-G-S-S-H-G-V-A-P-M-V-R-E-R-A-Q-M-V-W-S-L-S-K-L-T-F-P-H-E-L-A-R-V-I-V-L-E-Q-L-Y-R-A-V-T-I-L-A-G-H-P-Y-H-H-G


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-S-N-D-F-R-T-G-T-T-I-E-L-D-G-Q-V-W-R-V-I-E-F-L-H-V-K-P-G-K-G-S-A-F-V-R-T-K-L-K-N-V-M-T-G-N-V-N-E-R-T-F-R-A-G-E-T-L-P-Q-A-V-V-E-K-R-D-M-Q-F-V-Y-P-Q-G-D-N-E-Y-V-F-M-D-M-E-S-Y-E-Q-E-A-L-T-R-E-T-L-G-D-G-A-K-Y-L-K-E-G-M-S-V-S-I-L-K-W-Q-E-R-V-I-G-V-D-L-P-N-T-V-V-L-Q-V-V-E-T-D-P-G-V-K-G-D-T-A-Q-G-G-T-K-P-A-K-V-E-T-G-A-E-V-M-V-P-L-F-I-T-I-G-E-K-I-K-I-D-T-R-D-N-S-Y-L-G-R-E-N


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-R-A-Y-R-L-G-E-D-L-G-T-G-A-K-C-V-K-F-L-I-N-L-A-S-T-P-S-M-A-V-V-P-T-A-V-E-L-C-I-Q-A-A-V-D-D-P-V-G-E-A-R-W-Q-S-W-F-D-Q-W-L-L-E-L-Q-S-A-G-A-V-E-L-T-L-R-L-T-D-D-A-E-I-R-R-L-N-A-R-F-R-G-V-D-A-P-T-D-V-L-S-F-E-F-E-A-D-D-T-Q-A-L-I-A-E-E-P-L-Y-L-G-D-I-V-V-S-V-P-T-A-T-R-Q-A-R-E-F-G-H-T-L-E-V-E-L-A-W-L-A-V-H-G-L-L-H-L-L-G-W-D-H-P-D-E-Q-S-W-R-A-M-V-T-Q-Q-A-R-L-L-K-G-V-N-V-V-Y-D-W-P-S-V-Y-P-V-G


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-V-V-S-V-L-G-L-D-V-G-S-K-R-I-G-V-A-G-C-D-P-T-G-L-I-A-S-G-L-E-T-I-V-R-C-N-L-G-A-D-L-D-A-I-R-H-W-I-E-R-R-R-A-Q-A-V-V-I-G-L-P-R-N-M-N-G-S-L-G-P-Q-A-H-R-I-Q-H-F-G-Q-Q-L-A-R-V-I-D-V-P-I-D-Y-V-D-E-R-L-S-T-V-Q-A-G-R-A-L-Q-S-V-S-A-T-R-R-K-A-L-I-D-Q-Q-A-A-A-I-I-L-Q-Q-W-L-D-I-R-R-C-Q-H-R-P-T-Q-E-S-L-D-E-R-H-I-D-T-E-R


### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-T-G-E-I-F-F-V-A-G-L-V-F-V-L-T-L-V-G-M-A-I-G-F-G-V-L-K-L-R-G-E-G-K-E-A


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-V-F-E-G-N-L-Q-D-T-R-D-L-K-F-A-I-V-I-A-R-F-N-D-L-V-V-G-K-L-L-S-A-C-E-D-S-L-R-R-H-G-V-A-V-G-P-D-S-H-Q-V-D-Y-A-W-V-P-G-S-F-E-I-P-M-V-A-R-Q-L-A-L-S-G-R-Y-D-A-I-V-C-L-G-A-V-I-R-G-Q-T-S-H-Y-D-H-V-A-S-E-V-A-K-G-I-Q-A-L-A-F-Q-T-G-V-P-V-T-F-G-V-L-T-T-D-T-M-Q-Q-A-I-E-R-A-G-I-K-S-N-L-G-W-E-Y-G-E-N-A-I-E-M-A-T-L-T-R-K-I-R-H-L-V-A-V-R-A-V-Q-P-E-L-P-E-Q-T-P-P-S-L-L-Q


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-V-F-V-A-D-H-L-L-R-K-I-E-T-M-N-S-K-N-E-K-R-V-I-K-T-W-S-R-A-S-T-I-V-P-Q-M-I-G-H-T-I-A-V-H-N-G-K-E-H-L-P-V-Y-V-T-E-Q-M-V-G-Q-K-L-G-E-F-V-P-T-R-V-F-K-G-H-A-G-K-D-K-K-G-K-R


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-P-Q-R-I-P-L-W-M-V-G-V-M-A-G-L-G-V-I-A-I-L-G-L-F-F-Y-G-S-Y-A-G-L-G-A-G


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-S-K-D-P-K-N-P-G-V-E-L-N-R-T-S-L-Y-M-G-L-V-L-V-L-V-I-I-L-L-F-S-N-Y-F-I-N


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-A-Q-E-I-I-R-S-I-E-A-E-Q-M-K-T-Q-L-P-V-L-H-I-G-D-T-V-K-V-N-V-R-I-R-E-G-G-K-E-R-I-Q-A-F-E-G-T-I-I-S-M-A-R-A-G-I-N-R-T-V-T-V-R-R-I-F-Q-G-I-G-V-E-R-V-F-L-V-H-S-P-R-I-E-S-M-T-V-T-R-L-G-K-V-R-R-A-K-L-Y-Y-L-R-D-R-I-G-K-A-T-R-V-K-Q-K-I-T-R-K-A-N


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-V-Y-A-I-V-E-T-G-G-K-Q-V-L-V-Q-P-G-R-F-Y-D-V-E-L-L-A-L-D-V-E-A-A-L-T-F-D-K-V-L-L-V-R-H-E-G-G-A-V-V-G-R-P-T-V-E-G-A-A-V-Q-G-R-I-L-Q-H-G-K-A-A-K-V-T-V-Y-K-M-R-P-K-K-G-Y-R-R-K-K-G-H-R-Q-R-F-T-R-V-M-I-E-S-I-D-F-E-G-R-S-F-T-A-E-A-K-A-E-A-V-S-S-T


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-T-E-T-L-E-R-K-S-V-Q-R-K-P-M-P-L-Y-K-V-L-L-H-N-D-D-H-T-P-M-N-Y-V-I-E-V-L-M-K-T-I-P-K-M-Q-P-S-K-A-R-K-I-M-L-E-A-H-N-G-G-V-A-V-V-I-V-C-A-L-E-H-A-E-F-Y-S-E-S-L-N-R-H-N-L-T-S-T-Y-E-P-D-C


### FUNCTION Essential for the assembly of the photosystem I  complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-N-Q-R-N-D-N-F-I-D-K-S-F-T-V-M-A-D-M-I-L-Q-M-M-P-V-K-R-Q-A-K-E-A-F-A-Y-Y-R-D-G-M-A-A-Q-A-D-G-D-Y-A-E-A-L-E-Y-Y-N-E-A-L-K-L-E-E-D-A-Y-D-R-S-F-I-H-Y-N-I-G-L-I-H-A-A-N-G-A-H-D-V-A-L-D-Y-Y-D-K-A-L-E-E-N-P-R-L-P-Q-A-L-N-N-I-A-V-I-H-H-F-R-G-A-K-V-E-E-E-G-Q-P-E-Q-A-E-E-H-Y-A-K-A-A-A-A-W-I-R-A-V-R-L-A-P-D-N-Y-I-E-A-Q-N-W-L-K-T-T-G-R-F-E-L-L-Y


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-P-F-G-L-G-L-P-E-I-L-V-I-G-V-I-A-L-L-I-F-G-P-K-K-L-P-E-M-G-S-A-L-G-K-A-I-R-G-F-K-S-G-V-S-D-E-P-A-P-Q-Q-S-A-S-K-E-T-A-P-N-P-P-Q-S-L-P-S-G-K-D-S


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-S-F-W-S-K-V-K-D-F-V-G-F-G-D-P-L-E-Y-E-E-D-G-E-E-Y-E-Q-V-Y-R-E-E-N-K-R-E-E-A-R-R-A-T-A-G-T-A-A-A-A-T-P-T-A-A-A-Q-A-S-D-A-A-P-M-G-S-G-P-A-R-K-R-V-R-A-G-N-V-I-G-M-P-N-S-G-V-N-E-V-L-V-I-E-P-R-S-F-E-E-A-P-Q-I-V-Q-H-L-R-D-R-K-S-V-I-L-N-L-T-L-M-D-S-D-Q-A-Q-R-S-V-D-F-V-A-G-A-T-F-A-I-D-G-H-Q-E-R-V-G-D-G-I-F-L-F-T-P-S-S-V-M-I-S-T-E-M-P-S-Q-L-R-Q-A-N-Q-A-F-G-G-N-F-R-L-N-P-E-A-P-R-R-A-Q-G


### FUNCTION Part of the high-affinity ATP-driven potassium transport  system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-S-P-L-Q-E-I-G-T-A-V-R-M-T-A-I-F-W-I-G-C-G-L-A-Y-P-L-I-F-T-G-F-A-Q-V-A-F-P-D-Q-A-N-G-S-L-V-R-N-A-Q-N-Q-V-I-G-S-S-L-I-G-Q-K-F-T-S-E-R-Y-F-H-G-R-P-S-S-I-D-Y-K-A-E-A-S-G-A-S-Q-L-A-P-T-N-K-V-L-I-E-R-V-K-A-D-A-A-A-F-E-A-Q-N-G-T-K-P-T-I-D-L-V-T-T-P-G-S-G-L-D-P-H-I-T-P-A-G-A-A-V-Q-T-A-R-V-S-R-A-R-N-L-A-P-E-Q-V-R-K-L-V-S-Q-Y-T-E-G-R-F-L-G-I-F-G-E-P-R-V-N-V-L-A-L-N-L-A-L-D-G-I-R-R


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-E-L-R-L-F-V-G-L-G-N-P-G-L-Q-Y-T-Q-T-R-H-N-A-G-F-L-A-V-D-A-L-A-K-R-W-Q-C-S-W-V-E-K-S-R-F-K-G-Y-L-A-E-G-A-G-P-G-G-R-A-I-L-L-K-P-T-T-Y-M-N-H-S-G-Q-S-V-R-A-V-A-D-Y-F-R-L-P-P-Q-Q-L-L-V-L-Y-D-E-V-A-L-P-L-G-K-I-R-L-R-P-E-G-S-A-A-G-H-N-G-I-K-S-L-I-E-H-L-G-T-N-Q-F-A-R-L-R-I-G-I-G-R-E-P-P-P-P-V-L-T-N-Y-V-L-G-K-F-A-P-E-E-Q-E-Q-L-P-A-I-L-D-G-C-V-E-A-V-E-A-V-L-A-K-G-L-E-K-A-M-S-I-Y-N-A-R-S-F-G-S-P-P-D-P


### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-I-E-P-I-L-L-G-M-V-L-G-F-V-P-V-T-I-A-G-L-L-V-A-A-W-L-Q-Y-K-Q-G-N-P-S-G-L-G-E-K


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-T-K-Y-E-T-M-Y-I-L-R-P-D-L-T-D-E-I-I-D-Q-T-I-T-R-Y-Q-T-L-L-A-E-Q-G-A-A-P-V-E-T-Q-H-R-G-K-R-R-L-A-Y-E-L-K-K-F-K-E-G-I-Y-V-Q-M-N-Y-D-A-P-T-T-A-V-A-E-L-E-K-A-F-R-L-S-E-E-V-I-R-F-L-T-V-R-E-E-D


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-Q-D-V-I-E-M-E-G-T-V-V-E-S-L-P-N-A-M-F-R-V-E-L-D-N-S-F-N-I-L-A-H-I-S-G-K-I-R-R-N-Y-I-K-I-L-P-G-D-R-V-K-V-E-L-T-P-Y-D-L-T-K-G-R-I-T-Y-R-L-R-K


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-N-V-S-K-T-E-Q-D-M-R-K-A-I-E-A-T-A-G-N-F-A-T-I-R-T-G-R-A-S-T-S-L-L-D-R-I-N-V-E-Y-Y-G-Q-P-T-P-L-K-T-L-A-T-I-T-T-P-D-A-S-T-V-L-I-Q-P-Y-D-P-S-S-L-R-L-I-E-K-T-I-L-E-S-D-L-G-L-P-P-S-N-D-G-K-T-I-R-L-N-I-P-P-L-T-A-E-R-R-K-D-L-V-K-V-L-R-N-L-A-E-E-G-R-V-A-V-R-N-I-R-R-H-A-I-D-E-V-R-K-E-E-K-D-A-K-V-S-E-D-E-A-R-R-L-Q-D-E-V-Q-K-L-T-D-K-S-I-Q-Q-I-E-K-L-F-E-A-K-E-K-E-I-T-T-V


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-N-I-K-S-A-I-K-R-V-D-V-A-E-R-N-R-Q-R-N-I-A-Y-K-S-M-I-K-T-F-T-K-K-F-M-T-R-L-G-E-Y-A-Q-S-P-S-E-A-V-L-T-E-V-Q-A-L-L-N-Q-T-F-S-R-I-D-K-A-I-K-A-G-V-I-H-T-N-T-G-A-R-K-K-S-R-L-D-A-A-L-R-T-A-L-A-K-A-Q-A-K-A-G


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-L-C-P-F-C-S-Y-S-D-N-R-V-L-E-S-R-L-A-E-E-G-E-S-V-R-R-R-R-E-C-K-Q-C-R-R-R-F-T-T-Y-E-R-I-E-F-V-P-T-V-V-I-K-R-N-G-R-R-E-A-F-D-R-S-K-V-L-R-G-V-M-I-A-C-E-K-T-D-V-P-A-E-L-I-E-Q-L-V-D-D-L-Q-A-E-L-Q-Q-R-S-S-R-E-V-T-S-A-E-I-G-E-M-V-L-A-L-L-K-P-L-N-E-V-A-Y-V-R-F-A-S-V-Y-R-K-F-K-G-V-A-D-F-V-S-E-L-Q-T-F-E-A-N-A-E-L-D-S-L-K-A-R-L-E-R-L-A-A-A-H-D-Q-S-A-D


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-S-G-T-K-R-A-L-A-D-I-I-R-R-P-L-I-T-E-K-G-T-R-L-L-E-E-N-K-Y-L-F-E-V-T-P-G-A-N-K-I-Q-I-A-Q-A-I-E-E-L-F-S-V-K-V-T-K-V-N-T-F-N-P-P-A-R-Q-R-R-V-G-K-Y-L-G-T-R-S-S-Y-K-R-A-I-V-T-L-Q-E-G-D-S-I-T-L-F-P-E-V


### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-A-A-P-A-I-Y-Q-T-D-K-V-L-R-F-E-V-P-G-S-R-R-P-S-T-Y-F-F-A-L-V-L-T-L-G-G-L-G-F-L-F-A-G-L-S-P-F-V-E-T-N-L-L-P-F-S-D-T-R-G-L-T-R-F-P-Q-G-V-T-M-I-F-Y-G-A-L-A-T-L-F-S-L-Y-Y-W-L-V-L-A-L-D-V-G-S-G-Y-N-E-F-D-K-Q-N-K-K-V-T-L-F-R-R-G-F-P-G-K-N-R-I-I-E-I-V-H-P-L-E-N-I-L-G-L-K-V-Q-I-K-E-G-L-N-P-R-R-A-Y-F-L-K-L-K-G-A-R-D-L-R-L-S-P-V-G-Q-P-Q-P-L-A-A-V-E-D-Q-V-S-A-I-A-R-F-L-N-I-G-V-E-G-I


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-S-A-Y-R-F-R-R-A-H-R-L-L-K-T-D-E-F-S-S-V-F-S-L-R-Q-Q-R-S-N-A-F-F-Q-V-F-A-R-P-N-G-L-D-H-A-R-V-G-L-V-V-G-K-K-V-A-K-R-A-V-R-R-N-Y-I-K-R-C-V-R-E-W-F-R-L-N-Q-Q-G-L-D-G-V-D-Y-V-V-R-A-K-T-A-F-T-R-E-Q-R-A-E-A-V-T-A-L-Q-A-L-F-A-K-L-A-R-C-R-A-S-S-S-S


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-L-T-H-Q-D-V-A-R-I-A-K-L-A-R-I-N-V-S-E-A-E-I-A-A-T-A-D-Q-L-N-N-I-F-G-L-I-E-K-M-Q-A-V-D-T-A-G-I-E-P-M-A-H-P-Q-D-V-S-L-R-L-R-D-D-V-V-T-E-P-N-R-R-E-A-F-Q-A-V-A-P-Q-V-E-K-G-L-F-L-V-P-K-V-I-E


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-L-L-N-I-L-H-Y-P-D-E-R-L-H-T-V-A-K-P-V-E-V-F-D-A-A-L-Q-Q-Q-I-D-D-M-F-E-T-M-Y-E-A-K-G-I-G-L-A-A-T-Q-V-D-Y-H-R-R-L-V-V-M-D-I-S-E-E-R-D-E-R-R-V-F-I-N-P-E-I-V-E-K-D-G-E-T-V-Y-E-E-G-C-L-S-V-P-G-I-Y-D-K-V-T-R-A-E-R-V-K-V-K-A-Q-D-R-D-G-K-P-F-E-L-E-A-D-G-L-L-A-I-C-I-Q-H-E-L-D-H-L-N-G-V-V-F-V-E-R-L-S-Q-M-K-Q-Q-R-I-K-T-K-L-K-K-R-E-K-Q-N-M


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-L-S-G-K-L-I-E-K-L-P-P-Q-V-V-V-D-V-N-G-V-G-Y-E-V-D-V-P-M-T-T-F-Y-Q-L-P-A-L-G-Q-P-C-T-L-F-T-H-L-A-V-R-E-D-A-H-L-L-Y-G-F-A-S-K-E-E-R-Q-T-F-R-Q-L-I-K-V-T-G-I-G-A-K-I-A-L-A-I-L-S-G-M-T-A-D-E-L-A-I-A-V-A-S-E-D-I-K-R-L-S-A-V-P-G-I-G-K-K-T-A-E-R-L-V-L-E-L-R-G-K-L-A-T-G-G-N-L-T-V-P-G-G-L-P-F-A-A-T-P-D-E-K-S-D-I-V-N-A-L-L-A-L-G-Y-N-E-K-E-A-A-A-A-T-K-S-L-P-A-D-V-T-V-S-E-G-V-R-L-A-L-K-S-L-M-K-V


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-L-N-I-E-D-K-K-A-V-V-A-E-V-S-A-Q-L-A-E-A-Q-T-L-V-I-A-E-Y-R-G-I-E-V-S-S-M-T-K-L-R-A-Q-A-R-E-N-G-V-Y-L-R-V-L-K-N-T-L-V-R-R-A-V-E-G-T-P-F-A-G-L-A-D-Q-M-V-G-P-L-V-Y-A-V-S-A-D-P-V-A-A-A-K-V-L-H-Q-F-A-K-A-D-D-K-I-I-V-K-A-G-S-Y-D-G-Q-V-L-N-A-A-Q-V-A-E-L-A-S-I-P-S-R-E-E-L-L-S-K-L-L-Y-V-M-Q-A-P-V-A-G-F-A-R-A-L-A-A-L-A-E-K-Q-A-E-A-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-I-T-K-E-D-I-L-E-A-V-A-G-L-T-V-M-E-L-N-D-L-V-K-A-F-E-E-K-F-G-V-S-A-A-A-V-A-V-A-G-P-A-G-A-G-A-A-A-A-E-E-K-T-E-F-D-V-V-L-S-A-A-G-D-N-K-V-G-V-I-K-V-V-R-A-I-T-G-L-G-L-K-E-A-K-D-L-V-D-G-A-P-K-N-V-K-E-G-V-A-K-A-E-A-E-D-I-V-K-Q-L-T-E-A-G-A-K-A-E-I-K


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-K-G-R-V-A-I-T-A-K-S-K-V-P-A-L-E-A-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-K-V-R-L-T-N-G-F-E-V-I-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-S-L-D-T-A-G-V-K-D-R-K-Q-A-R-S-K-Y-G-A-K-R-P-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-E-V-P-K-R-E-I-L-P-D-P-K-F-G-S-Q-D-L-S-K-F-M-N-V-V-M-I-D-G-K-K-S-V-A-E-R-I-I-Y-G-A-L-E-Q-I-E-K-K-T-G-K-N-A-I-E-V-F-N-T-A-L-S-N-A-K-P-V-V-E-V-K-S-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-R-P-S-R-R-M-A-L-A-M-R-W-L-R-D-A-A-R-K-R-G-E-K-S-M-D-L-R-L-A-G-E-L-I-D-A-A-E-G-R-G-G-A-M-K-K-R-D-E-V-H-R-M-A-E-A-N-K-A-F-S-H-F-R-F


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-S-Q-K-I-R-I-R-L-K-A-F-D-Y-N-L-I-D-R-S-A-Q-E-I-V-E-T-A-K-R-T-G-A-V-V-K-G-P-V-P-L-P-T-K-I-E-R-F-N-V-L-R-S-P-H-V-N-K-T-S-R-D-Q-L-E-I-R-T-H-L-R-L-M-D-I-V-D-P-T-D-K-T-V-D-A-L-M-K-L-D-L-P-A-G-V-D-V-E-I-K-L-Q


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-Q-E-R-L-L-Q-V-I-L-A-P-I-V-S-E-K-S-T-M-I-A-E-K-N-Q-Q-V-A-F-R-V-A-K-D-A-T-K-P-E-I-K-A-A-V-E-M-L-F-N-V-K-V-D-G-V-S-T-V-N-V-K-G-K-V-K-R-F-G-R-T-I-G-R-R-S-D-W-K-K-A-Y-V-S-L-V-D-G-Q-E-L-D-L-T-A-T-P-A-A-A-E


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-Q-K-K-G-P-F-V-D-L-H-L-L-K-K-V-D-A-V-R-A-T-S-D-K-R-P-I-K-T-W-S-R-R-S-T-I-L-P-D-F-I-G-L-T-I-A-V-H-N-G-R-T-H-V-P-V-Y-V-S-E-N-M-V-G-H-K-L-G-E-F-S-L-T-R-T-F-K-G-H-A-A-D-K-K-A-K-K-K


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-R-V-S-A-N-L-K-S-V-R-L-S-A-Q-K-C-R-L-V-A-D-L-V-R-G-K-S-V-D-Q-A-L-N-I-L-A-F-S-P-K-K-G-A-V-I-I-K-K-V-L-E-S-A-I-A-N-A-E-H-N-E-G-A-D-I-D-T-L-R-V-T-S-I-F-V-D-K-G-A-S-L-K-R-F-T-A-R-A-K-G-R-G-N-R-I-E-K-Q-T-C-H-I-S-L-T-V-G-N


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-T-R-L-K-Y-R-K-Q-H-K-G-R-N-T-G-I-A-T-R-G-N-K-V-S-F-G-D-F-G-L-K-A-I-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-H-I-K-R-G-G-R-I-W-I-R-I-F-P-D-K-P-I-T-S-K-P-A-E-V-R-M-G-G-G-K-G-S-P-E-Y-Y-V-A-E-I-Q-P-G-K-M-L-Y-E-M-D-G-V-S-E-E-L-A-R-E-A-F-R-L-A-A-A-K-L-P-I-A-T-V-F-V-T-K-Q-V-G-Q


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-T-K-V-V-R-T-L-T-G-V-V-V-S-D-K-M-D-K-T-V-T-V-L-V-E-R-K-V-K-H-P-I-Y-G-K-I-I-R-R-S-K-K-F-H-A-H-D-E-N-N-E-F-K-A-G-D-L-V-V-I-S-E-S-R-P-L-S-K-T-K-S-W-V-V-T-G-L-V-E-K-S-R-Q-V


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-M-L-E-V-A-D-N-T-G-A-R-H-V-Q-C-I-K-V-L-G-G-S-K-R-R-Y-A-S-V-G-D-I-I-K-V-S-I-K-D-A-A-P-R-G-R-V-K-K-G-D-V-Y-N-A-V-V-V-R-T-A-K-G-V-R-R-P-D-G-S-L-I-K-F-D-S-N-A-A-V-L-L-N-N-K-L-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-R-F-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-R-K-I-R-K-G-D-E-V-V-V-I-T-G-K-D-K-G-K-R-G-T-V-L-R-V-L-E-T-K-L-V-V-E-G-V-N-V-A-K-K-H-Q-K-P-N-P-V-R-G-V-A-G-G-I-V-E-K-T-M-P-I-D-A-S-N-V-A-I-F-N-P-A-S-Q-K-A-D-R-V-G-F-K-V-L-E-D-G-R-K-V-R-V-F-K-S-S-G-E-V-I-G-A


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-R-L-Y-D-F-Y-K-D-S-V-V-P-E-L-M-K-Q-F-G-Y-K-S-I-M-Q-V-P-R-I-E-K-I-T-V-N-M-G-V-G-E-A-V-A-D-K-K-V-M-E-F-A-V-G-D-L-E-K-I-A-G-Q-K-P-V-V-T-T-A-R-K-S-I-A-G-F-K-I-R-D-D-Y-P-V-G-C-K-V-T-L-R-R-E-R-M-Y-E-F-L-D-R-L-V-T-I-A-L-P-R-V-R-D-F-R-G-V-S-A-K-S-F-D-G-R-G-N-Y-N-M-G-V-K-E-Q-I-I-F-P-E-I-E-Y-D-K-I-D-A-L-R-G-M-N-I-T-I-T-T-S-A-K-T-D-E-E-A-R-A-L-L-A-A-F-K-F-P-F-K-G


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-R-L-A-L-I-N-R-E-E-K-R-V-K-L-A-E-K-F-S-A-K-R-E-A-L-I-A-T-I-N-N-Q-N-L-S-E-E-E-R-F-A-A-R-L-Q-L-Q-Q-L-P-R-N-A-S-P-V-R-Q-R-R-R-C-A-V-T-G-R-P-R-G-V-F-R-K-F-G-L-G-R-N-K-L-R-E-I-A-M-K-G-E-I-P-G-V-V-K-A-S-W


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-H-D-P-I-S-D-M-L-T-R-I-R-N-G-Q-H-A-S-K-V-K-V-S-M-P-S-S-K-L-K-I-A-L-A-Q-V-L-K-E-E-G-Y-I-E-D-F-A-I-A-G-E-E-K-K-P-V-L-D-I-Q-L-K-Y-Y-A-G-R-P-V-I-E-R-I-E-R-V-S-R-P-G-L-R-V-Y-K-G-S-T-E-I-P-K-V-M-N-G-L-G-V-A-I-L-S-T-S-K-G-V-M-T-D-R-K-A-R-A-A-G-I-G-G-E-L-L-C-V-V-A


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-N-P-V-A-I-P-A-G-V-E-V-K-F-G-A-A-D-V-T-V-K-G-A-L-G-S-L-S-T-A-L-C-N-D-V-E-V-K-L-D-N-G-Q-L-T-F-A-A-K-N-D-S-K-F-A-R-A-M-S-G-T-L-R-A-L-L-N-N-M-V-N-G-V-S-K-G-F-E-K-K-L-Q-L-V-G-V-G-Y-R-A-Q-A-Q-G-D-T-L-N-L-S-L-G-F-S-H-P-V-A-H-K-M-P-A-G-I-K-V-E-T-P-T-Q-T-E-I-L-V-K-G-A-D-K-Q-L-V-G-Q-V-A-A-E-I-R-A-Y-R-S-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-V-V-V-L-K-E-T-K-K-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-Q-T-R-L-R-R-A-R-K-T-R-A-R-I-A-E-L-K-M-V-R-L-S-V-H-R-T-N-S-H-I-Y-A-Q-I-I-D-E-T-G-N-K-V-L-A-S-A-S-S-L-E-A-D-V-R-S-A-M-A-N-G-G-N-V-A-A-A-A-V-I-G-K-R-I-A-E-K-A-K-A-A-G-I-E-Q-V-A-F-D-R-S-G-F-K-Y-H-G-R-M-K-A-L-A-D-A-A-R-E-H-G-L-V-F


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-K-H-E-M-E-D-R-G-D-G-L-V-E-K-M-I-S-V-N-R-V-T-K-V-V-K-G-G-R-I-M-A-F-S-A-L-T-V-V-G-D-G-D-G-G-I-G-M-G-K-G-R-S-K-E-V-P-V-A-V-Q-K-A-M-E-Q-A-R-H-N-M-M-K-I-K-L-Y-N-G-T-V-K-H-T-V-E-G-R-H-G-A-T-R-V-L-I-Q-P-A-K-D-G-T-G-V-K-A-G-G-P-M-R-A-I-F-D-A-M-G-I-H-N-V-S-A-K-I-H-G-S-T-N-P-Y-N-V-V-R-A-T-L-D-G-L-S-K-I-N-T-P-A-Q-I-A-A-K-R-G-L-S-I-E-D-I-L-G-V-G-H-E


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-L-L-N-T-V-Q-P-G-V-G-A-K-H-A-K-R-R-V-G-R-G-I-G-S-G-L-G-K-T-C-G-R-G-H-K-G-Q-K-S-R-A-G-G-F-H-K-V-G-F-E-G-G-Q-M-P-L-Q-R-R-L-P-K-R-G-F-K-S-L-T-A-R-F-V-C-E-V-R-L-S-E-L-N-L-L-P-V-D-E-I-D-L-L-A-L-K-Q-A-G-L-V-A-A-Q-A-Q-V-A-K-V-V-L-S-G-K-V-E-R-A-V-K-L-R-G-I-S-V-T-A-G-A-R-A-A-I-E-A-A-G-G-S-I-E


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-D-T-I-Q-M-Q-G-E-V-L-E-N-L-P-S-A-T-F-K-I-K-L-E-N-G-H-V-V-L-G-H-I-S-G-K-M-R-M-H-Y-I-R-I-L-P-G-D-K-V-T-V-E-L-T-P-Y-D-L-S-R-A-R-I-V-F-R-A-K


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-N-H-A-H-A-V-I-G-L-Q-A-I-F-G-V-G-Q-T-R-A-Q-Q-I-C-A-A-A-S-V-N-P-S-T-K-V-K-D-L-T-E-A-E-M-E-A-L-R-D-Q-V-A-K-F-T-V-E-G-D-L-R-R-E-I-T-M-S-I-K-R-L-M-D-M-G-C-Y-R-G-F-R-H-R-R-G-L-P-C-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-K-A-I-A-G-K-K


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-A-N-T-A-V-R-V-R-K-K-V-R-K-S-V-S-E-G-I-V-H-V-H-A-S-F-N-N-T-I-I-T-I-T-D-R-Q-G-N-A-L-S-W-A-T-S-G-G-A-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-H-A-G-K-V-A-Q-E-Y-G-V-K-N-L-E-V-R-I-K-G-P-G-P-G-R-E-S-A-V-R-A-L-N-S-L-G-F-K-I-T-S-I-S-D-V-T-P-V-P-H-N-G-C-R-P-P-K-K-R-R-I


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-K-K-A-K-R-N-P-L-L-A-R-L-A-G-R-L-E-L-T-L-D-V-R-S-D-A-A-A-L-P-P-P-A-L-I-R-R-A-C-Q-A-A-L-R-R-D-V-K-Q-A-Q-I-S-I-V-I-V-D-A-A-E-G-R-Q-L-N-N-D-Y-R-G-K-D-Y-A-T-N-V-L-S-F-A-L-N-E-G-E-P-V-E-G-L-P-L-F-G-D-L-V-L-C-A-P-V-V-E-Q-E-A-A-E-Q-N-K-A-L-M-A-H-Y-A-H-L-L-V-H-G-M-L-H-L-Q-G-F-D-H-E-E-D-A-E-A-E-A-M-E-V-L-E-T-V-I-V-K-Q-L-G-Y-P-D-P-Y-H-E-E-H-I


### FUNCTION Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein ### SEQUENCE -M-I-R-R-V-L-L-L-S-L-A-L-L-L-A-G-C-A-N-E-A-L-F-R-P-K-P-A-L-E-S-A-A-D-A-P-F-S-V-S-G-R-L-S-A-N-L-D-G-K-G-H-V-A-N-F-D-W-R-H-L-P-P-R-D-E-V-A-I-N-S-P-L-G-N-T-V-A-K-V-L-R-D-P-G-G-V-T-L-L-A-D-G-K-R-W-Q-A-D-D-V-E-S-L-T-R-Q-V-M-G-W-P-L-P-L-S-N-L-V-W-W-I-R-G-L-P-A-P-G-V-E-S-R-V-D-A-D-G-N-L-E-Q-Q-G-W-H-I-R-F-I-R-D-A-D-V-D-S-D-H-P-K-R-V-E-M-Q-R-E-G-L-T-V-K-V-V-V-Q-S-W-Q


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-S-Y-E-L-I-A-A-K-R-V-D-L-G-T-G-A-S-R-R-L-R-R-A-G-K-L-P-A-V-V-Y-G-A-G-K-D-A-V-S-L-E-L-D-H-N-T-L-Y-H-A-V-K-H-A-D-F-H-T-S-V-L-E-L-V-I-D-G-Q-K-E-Q-V-K-V-A-A-F-Q-M-H-P-Y-K-Q-Q-V-L-H-I-D-F-A-R-V


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-G-I-R-L-I-V-G-L-G-N-P-G-P-E-Y-E-K-T-R-H-N-A-G-F-W-L-V-D-E-L-C-W-Q-F-K-G-N-W-R-S-E-G-K-F-H-G-D-V-A-R-I-Q-I-E-G-Q-D-V-W-L-L-K-P-M-T-Y-M-N-L-S-G-Q-A-V-L-A-L-A-H-F-Y-K-I-L-P-D-E-I-L-V-V-H-D-E-L-D-L-A-P-G-V-A-R-F-K-Q-G-G-G-H-G-G-H-N-G-L-K-D-I-A-A-R-L-S-S-P-A-F-W-R-L-R-L-G-I-G-H-P-G-D-K-K-E-V-A-N-F-V-L-K-K-P-R-A-E-E-Q-Q-A-L-D-E-A-V-L-A-S-L-R-E-L-P-R-A-V-S-G-K-M-A-E-A-M-K-A-L-H-T-E-A-K


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-F-D-F-G-E-R-R-I-G-V-A-V-G-D-T-I-L-G-I-P-H-P-L-A-T-I-D-T-A-V-T-D-E-R-F-A-A-I-A-R-L-I-E-E-W-Q-P-R-Q-L-V-V-G-L-P-M-H-P-D-G-E-E-H-E-L-S-A-L-S-R-R-F-A-N-R-L-K-G-R-F-G-L-P-V-W-L-V-D-E-R-Y-T-S-V-I-A-E-Q-L-L-E-E-A-G-V-K-K-G-R-K-Q-K-P-A-L-D-Q-V-A-A-Q-A-I-L-A-G-W-F-E-Q-P-G-T-A-V


### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-S-E-S-V-R-I-V-A-C-P-T-C-K-A-E-V-R-W-E-P-Q-S-R-Y-R-P-F-C-S-E-R-C-R-L-I-D-L-G-Q-W-A-S-E-S-Y-R-V-P-A-E-E-D-H-P-P-G-E-T-P-P-T-H


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-I-S-K-Y-N-R-P-M-E-N-L-S-N-L-D-Y-S-S-Y-L-K-G-W-I-R-T-V-P-N-W-P-Q-Q-G-V-M-F-R-D-I-T-P-L-L-Q-N-P-K-T-F-R-M-L-I-D-I-Y-V-H-R-Y-M-M-E-K-V-D-L-V-A-G-L-D-A-R-G-F-I-I-G-S-V-L-A-Y-E-L-N-V-G-F-V-P-I-R-K-K-G-K-L-P-F-T-T-V-E-E-E-Y-E-L-E-Y-G-N-A-A-V-E-M-H-T-D-A-C-K-P-G-D-R-V-I-L-I-D-D-L-V-A-T-G-G-T-M-M-A-G-Y-K-L-L-K-R-M-G-A-D-V-L-E-A-A-A-I-I-E-L-P-E-L-G-G-G-Q-L-V-R-D-G-G-L-D-L-F-T-V-C-S-Y-E-G-H


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-V-D-D-C-L-D-R-I-Q-N-R-F-D-L-T-L-A-A-A-Y-R-A-R-Q-V-A-S-G-A-S-A-F-V-E-P-G-R-H-K-P-T-V-I-A-L-R-E-I-A-A-G-H-V-G-K-E-V-L-N-R-G-K-A


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-S-A-Q-A-R-K-R-A-R-T-A-L-K-Q-R-A-H-N-A-S-L-R-T-A-F-R-T-A-V-K-K-V-L-K-A-I-E-A-G-D-K-A-A-A-R-V-V-F-Q-A-S-E-K-V-I-D-R-I-A-D-K-G-V-F-H-K-N-K-A-A-R-H-K-S-R-L-S-A-Q-I-K-A-M-A


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-S-A-K-A-H-E-V-K-R-E-W-Y-V-V-D-A-A-D-K-V-L-G-R-L-A-A-E-I-A-R-R-L-R-G-K-H-K-P-E-F-T-P-H-V-D-T-G-D-F-I-V-V-V-N-V-E-K-L-R-V-T-G-T-K-A-Q-D-K-K-Y-Y-R-H-S-G-Y-P-G-G-I-Y-E-R-T-F-T-E-L-Q-N-Q-F-P-E-R-V-L-E-K-A-V-K-G-M-L-P-K-G-P-L-G-Y-A-M-I-K-K-L-K-V-Y-S-G-S-E-H-P-H-A-A-Q-Q-P-K-V-L-E-I


### FUNCTION Required for insertion of 4Fe-4S clusters ### SEQUENCE -M-T-E-A-A-T-E-M-P-S-P-I-N-F-T-E-S-A-C-A-K-V-Q-D-L-I-A-E-E-G-N-P-D-L-K-L-R-V-F-V-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-I-A-N-E-D-D-T-A-I-E-R-Q-G-V-T-F-L-V-D-P-M-S-Y-Q-Y-L-V-G-A-E-I-D-Y-Q-E-S-L-E-G-S-Q-F-V-I-R-N-P-N-A-T-T-T-C-G-C-G-S-S-F-S-V


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-R-D-E-D-L-V-V-M-G-F-V-R-G-A-F-G-I-K-G-W-V-K-I-H-A-D-T-E-Y-A-D-G-L-F-D-Y-P-T-W-W-L-G-K-N-G-S-W-K-P-Y-A-F-E-N-G-A-V-Q-P-K-A-L-A-A-K-L-E-G-V-D-D-R-D-A-A-E-A-L-R-G-T-Q-I-A-I-P-R-S-E-L-P-E-A-G-D-G-E-Y-Y-W-A-D-L-I-G-L-S-V-V-N-Q-Q-G-E-T-L-G-K-V-D-S-L-L-E-T-G-A-N-D-V-L-V-V-K-G-G-D-G-Q-Q-R-L-I-P-F-V-D-Q-Y-V-L-E-V-V-P-A-E-G-R-I-L-V-D-W-G-L-D-Y


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-D-L-I-Q-K-L-E-Q-E-E-I-A-R-L-G-K-T-L-P-E-F-A-P-G-D-T-V-V-V-Q-V-K-V-K-E-G-N-R-E-R-L-Q-A-Y-E-G-V-V-I-A-K-R-N-R-G-L-N-S-A-F-T-V-R-K-M-S-A-G-E-G-V-E-R-T-F-Q-T-Y-S-P-L-V-A-S-V-E-V-K-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-G-R-T-G-K-S-A-R-I-K-E-K-L-P-A-R-K-Q-G


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-K-V-D-M-S-T-S-V-K-D-D-A-Q-L-E-A-S-R-V-R-E-N-P-P-P-M-Y-K-V-L-L-L-N-D-D-F-T-P-M-D-F-V-V-Q-V-L-Q-Q-F-F-H-M-N-R-E-K-A-T-H-I-M-L-Q-V-H-T-Q-G-H-G-V-C-G-V-Y-T-K-D-V-A-A-T-K-V-E-Q-V-L-Q-Y-A-K-A-H-Q-H-P-L-Q-C-V-M-E-E-N


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-I-V-H-P-D-Q-S-E-Q-V-P-A-M-I-E-R-Y-K-G-M-V-L-A-A-E-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-Q-K-L-H-K-A-H-Y-V-L-M-N-V-E-C-Q-A-E-T-L-A-E-I-E-H-A-F-K-F-N-D-A-V-L-R-H-L-T-I-K-M-D-R-A-I-S-D-A-S-P-M-M-K-D-E-K-A-K-N-L-L-D-A-Q-P-A-A-E-V-E-A-S-A


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-Q-L-F-K-R-K-K-F-C-R-F-T-A-E-G-I-K-E-I-D-Y-K-S-V-D-L-L-K-D-F-I-A-E-N-G-K-I-I-P-A-R-I-T-G-T-K-A-R-Y-Q-R-Q-L-T-T-A-I-K-R-A-R-F-L-A-F-L-P-Y-T-D-Q-H


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-I-I-L-L-E-K-V-A-N-L-G-Q-L-G-D-V-V-N-V-K-N-G-F-A-R-N-F-L-I-P-Q-G-K-A-K-R-A-T-E-A-N-L-K-E-F-D-A-R-R-A-E-L-E-A-K-Q-A-E-I-L-A-D-A-K-V-R-A-E-K-L-N-E-A-V-I-T-I-A-Q-K-A-G-V-D-G-R-L-F-G-S-V-T-N-V-D-V-A-E-A-V-T-A-F-G-V-Q-I-K-R-H-E-V-R-L-P-N-G-P-F-K-A-I-G-E-Y-D-I-E-I-A-L-H-H-D-V-V-T-P-I-K-I-V-V-V-G-E-A


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-S-S-K-G-Q-M-L-Q-D-P-F-L-N-I-L-R-K-E-H-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-V-E-S-F-D-Q-Y-V-V-L-L-K-N-T-V-T-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-P-V-N-I-P-H-E-H-P-A-Q-K-Q-E-Q-A-Q-D-A


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-I-I-Q-N-R-K-A-F-H-D-Y-F-I-E-E-K-L-E-A-G-L-V-L-E-G-W-E-V-K-A-I-R-A-G-R-V-Q-L-K-E-S-Y-V-D-W-K-N-G-A-F-W-L-I-G-C-H-I-T-P-L-Q-S-A-S-T-H-V-K-P-D-P-V-R-P-R-K-L-L-M-S-Q-A-E-I-N-R-F-I-G-K-V-E-R-A-G-Y-T-M-M-A-L-D-L-H-Y-T-K-G-N-V-K-A-E-V-G-L-A-K-G-K-K-L-H-D-K-R-D-T-E-K-D-R-E-W-Q-R-E-K-Q-R-V-M-K-N-Q-R-G-A-A


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-W-L-T-V-T-L-V-T-V-I-L-A-L-Q-W-P-L-W-F-G-K-G-S-W-L-R-V-W-Q-L-D-K-Q-L-Q-E-Q-R-A-T-T-Q-K-L-V-A-R-N-A-A-L-D-A-E-V-R-D-L-K-Q-G-S-D-A-I-E-E-R-A-R-N-E-L-G-M-I-R-N-G-E-V-F-F-Q-L-L-D-P-S-K-N-P-S-R-A-S-H-R


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-I-P-A-E-L-K-Y-V-D-S-H-E-W-L-R-L-E-A-D-G-S-V-T-V-G-I-T-A-H-A-Q-E-L-L-G-D-I-V-F-V-E-L-P-K-V-G-A-S-L-A-K-D-E-Q-A-G-V-V-E-S-V-K-A-A-S-D-V-Y-C-P-I-A-G-E-V-L-A-V-N-E-E-L-E-G-E-P-E-L-A-N-S-D-P-Y-G-D-G-W-F-F-K-I-K-P-A-N-A-A-D-L-N-G-L-M-D-A-A-A-Y-A-K-E-I-G-A


### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-H-I-V-L-A-S-T-S-R-Y-R-Q-E-I-I-A-R-L-G-L-P-F-C-A-E-P-P-V-C-D-E-T-P-L-P-G-E-T-A-L-E-T-A-V-R-L-A-R-V-K-A-Q-S-L-A-G-K-H-P-E-A-L-I-I-G-S-D-Q-V-A-L-L-D-D-K-Q-I-G-K-P-G-G-F-E-Q-G-V-E-M-L-K-W-M-S-G-R-T-V-V-F-H-S-A-L-A-L-Y-N-T-A-S-G-R-L-Q-E-C-V-G-I-T-R-V-T-L-R-R-L-T-E-A-Q-I-R-N-Y-L-T-R-E-P-D-A-L-H-C-A-G-S-A-K-S-E-G-L-G-G-A-L-L-E-K-V-E-S-D-D-P-N-A-L-I-G-V-P-L-F-Q-L-I-T-M-L-G-N-E-G-V-E-V-L-K


### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-I-D-M-I-F-G-K-R-Q-K-S-A-A-I-A-R-E-R-L-Q-I-I-L-A-H-E-R-N-G-R-H-A-P-D-Y-L-P-A-L-Q-R-E-L-M-E-V-I-S-K-Y-V-S-V-N-L-E-D-I-K-V-Q-V-E-R-Q-D-D-Y-E-V-L-E-V-N-I-V-L-P-E-H-Q-R


### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-G-L-N-I-T-N-R-Q-G-F-L-L-V-A-A-A-C-A-G-A-I-G-F-A-L-F-A-Q-Y-Q-L-G-E-E-P-C-P-L-C-I-L-Q-R-I-G-V-M-A-V-G-A-L-A-L-L-A-A-L-H-N-P-G-K-T-G-A-K-V-W-G-G-L-M-T-L-A-A-L-S-G-A-G-V-S-L-R-Q-L-W-L-Q-S-L-P-A-D-Q-V-P-Q-C-G-P-G-L-E-F-L-M-E-S-F-P-L-W-E-V-L-S-K-V-L-K-G-S-G-E-C-A-A-I-Q-G-R-F-L-G-M-T-M-P-F-W-V-A-V-F-F-A-G-V-I-V-W-T-L-W-L-V-G-R-R-R-R-G


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-A-R-L-S-E-R-L-A-E-R-N-S-Q-L-V-Y-K-D-A-E-L-A-V-K-T-I-L-D-A-M-A-N-N-L-A-Q-G-S-R-I-E-I-R-G-F-G-S-F-D-L-N-Y-R-P-P-R-V-G-R-N-P-K-S-G-A-S-V-S-V-P-E-K-Y-V-P-H-F-K-A-G-K-E-L-R-E-R-V-D-L-S-L-L-E-Q-T-Q-A


### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-F-F-T-D-L-L-P-V-L-L-F-F-G-A-Y-W-L-T-R-D-M-F-V-A-T-G-V-A-I-A-A-T-A-V-M-V-A-W-A-W-F-K-H-R-K-V-D-T-M-Q-W-I-S-L-G-L-I-V-V-L-G-G-A-T-L-L-L-H-D-K-H-F-I-M-W-K-P-T-V-L-Y-W-V-M-G-A-G-L-L-I-S-E-F-A-G-K-N-G-L-R-L-M-M-G-K-Q-I-E-M-P-D-P-V-W-R-K-L-T-W-A-W-S-G-F-F-A-F-M-G-A-L-N-L-F-V-A-Y-H-F-S-E-D-V-W-V-N-F-K-L-F-G-G-M-G-L-M-L-L-F-V-I-A-Q-S-L-F-L-A-K-Y-I-E-E-K-K


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-K-A-A-K-A-P-A-S-F-E-T-A-L-A-Q-L-E-D-I-I-Q-A-M-D-S-G-D-M-P-L-E-T-A-L-A-S-Y-K-Q-G-T-E-L-I-K-F-C-Q-G-K-L-A-D-A-E-Q-Q-L-K-I-L-E-N-N-E-L-K-T-L-D-L-P-N-G-Q


### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate  May function as an ADP-ribosylase ### SEQUENCE -M-I-A-R-N-P-I-K-Q-D-P-A-M-R-N-T-Q-D-D-H-S-R-F-L-S-L-V-L-R-H-Q-P-E-T-I-G-L-Q-L-D-D-Q-G-W-A-D-I-G-E-L-L-A-R-L-A-A-K-G-R-N-L-G-R-K-Q-L-E-K-I-V-L-D-N-D-K-Q-R-F-A-I-S-E-D-G-L-R-I-R-A-N-Q-G-H-S-I-K-I-D-L-G-L-A-A-C-E-P-P-D-R-L-Y-H-G-T-A-S-R-F-L-D-A-I-L-A-E-G-L-R-P-G-Q-R-Q-H-V-H-L-S-A-D-G-Q-T-A-R-K-V-G-A-R-H-G-K-P-V-V-L-E-I-D-A-R-A-M-R-Q-A-G-L-A-F-Y-R-S-D-N-G-V-W-L-I-D-G-V-P-P-V-F-I-R-Q-T-E-A-R


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-K-T-A-R-R-R-A-R-E-F-A-V-Q-G-I-Y-E-W-E-L-N-P-D-R-P-A-S-L-I-E-K-H-L-R-E-N-E-Y-F-A-K-A-D-E-A-L-F-R-S-I-L-Y-G-V-L-K-D-V-E-L-L-S-A-Q-V-G-R-Y-Y-E-R-A-E-D-E-V-S-P-V-E-R-A-V-L-L-M-A-A-L-E-L-T-Q-S-P-E-T-P-Y-P-V-I-I-N-E-A-I-E-I-T-K-T-F-G-G-T-D-G-H-K-F-V-N-G-V-L-D-K-L-A-A-E-V-R-G-D-E-V-L-A-Q-K-Q-R-R-K-Q-D


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-L-D-A-I-Q-C-I-E-P-N-F-S-G-K-G-L-K-I-G-I-A-M-A-R-F-N-T-P-V-C-H-G-L-R-D-A-C-L-A-E-L-E-K-L-G-V-A-A-G-D-I-T-L-A-T-V-P-G-A-L-E-V-P-L-V-L-Q-T-M-A-K-S-G-R-F-D-A-L-V-A-L-G-A-V-I-R-G-E-T-Y-H-F-E-L-V-S-N-E-S-G-A-G-V-T-R-V-G-L-D-F-D-I-P-V-A-N-A-I-L-T-T-E-N-D-E-Q-A-E-V-R-M-L-E-K-G-G-D-A-A-R-V-A-V-E-M-A-N-L-H-K-T-L-R-G


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-Q-D-T-N-N-L-I-W-L-D-M-E-M-T-G-L-N-P-D-Q-D-R-I-I-E-V-A-M-I-V-T-D-S-N-L-N-V-L-A-E-S-P-V-L-V-I-H-Q-P-D-A-I-L-D-G-M-D-D-W-N-K-N-T-H-G-K-S-G-L-I-E-K-V-K-N-S-T-V-S-E-A-E-A-E-Q-L-L-L-E-F-M-M-Q-H-V-P-E-R-A-T-P-M-C-G-N-T-I-H-Q-D-R-R-F-M-A-R-W-M-P-K-L-E-A-Y-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-C-K-R-W-R-P-E-I-A-K-G-V-V-K-R-G-K-H-E-A-L-A-D-I-L-E-S-I-E-E-M-R-Y-Y-R-E-H-F-L-K-V


### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-K-A-I-L-G-G-G-C-F-W-C-L-E-A-A-F-S-Q-L-K-G-V-E-R-V-V-S-G-Y-C-G-G-H-T-D-S-P-D-Y-R-Q-V-C-S-G-D-S-G-H-V-E-V-V-E-I-S-Y-D-P-A-L-I-D-Y-A-T-L-L-Q-V-F-F-A-V-H-D-P-T-T-L-N-R-Q-G-H-D-V-G-T-Q-Y-A-S-A-I-F-Y-L-D-E-T-Q-R-E-C-A-R-R-V-I-A-Q-L-D-A-E-Q-I-F-D-A-P-I-V-T-R-V-E-S-A-P-R-F-H-P-A-E-D-Y-H-Q-N-Y-Y-A-Q-N-Q-Q-Q-N-Y-C-Q-L-V-I-S-P-K-L-A-K-I-R-R-R-F-S-H-L-L-Q-N


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-E-I-K-K-S-A-E-Q-K-M-Q-K-T-L-E-A-F-K-N-D-L-A-K-V-R-T-G-R-A-H-T-G-I-L-D-H-V-M-V-D-Y-Y-G-S-D-V-P-V-N-Q-V-A-N-V-T-L-I-D-A-R-T-I-G-V-Q-P-W-E-K-P-M-L-A-K-I-E-K-A-I-R-D-S-D-L-G-L-N-P-A-S-M-G-E-I-I-R-V-P-M-P-M-L-T-E-E-R-R-K-D-L-I-K-V-V-R-G-E-A-E-G-A-R-V-A-V-R-N-I-R-R-D-S-N-T-E-F-K-N-L-L-K-D-K-A-I-T-E-D-D-E-R-R-G-Q-D-E-I-Q-K-L-T-D-K-Y-T-A-E-I-D-K-M-L-A-T-K-E-A-D-L-L-A-V


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-Y-G-I-G-T-D-L-V-E-I-A-R-M-E-A-W-C-R-R-W-G-E-K-A-G-R-R-L-L-T-A-A-E-Q-A-E-F-A-A-H-A-E-P-A-R-F-L-A-K-R-F-A-A-K-E-A-F-A-K-A-L-G-T-G-V-V-A-P-A-L-L-T-A-I-G-V-G-H-D-E-L-G-K-P-V-L-I-L-S-D-E-L-A-A-F-A-A-A-R-G-I-A-R-M-H-L-S-I-S-D-E-R-G-H-A-L-A-F-V-V-L-E-S


### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-R-F-D-S-N-Q-L-G-N-V-E-V-D-E-T-T-I-I-T-F-P-Q-G-I-P-A-L-E-N-C-T-R-F-K-L-F-H-D-I-T-Q-P-T-P-Q-M-Y-W-L-Q-S-L-D-D-P-G-I-T-F-S-L-A-L-P-D-R-L-G-V-R-F-Q-I-E-L-S-D-E-E-V-A-Q-L-Q-L-S-G-P-Q-D-A-A-I-L-L-M-L-Y-R-P-L-D-L-D-R-D-S-H-P-V-L-G-A-L-Q-A-N-L-C-N-P-L-V-I-S-L-S-S-R-R-G-I-Q-K-T-G-L-K-I-D-I-L-L-H-T-P


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-W-K-S-I-L-A-I-A-I-G-A-A-A-G-A-L-L-R-W-F-L-G-L-R-L-N-S-L-F-P-S-L-P-P-G-T-L-A-A-N-L-V-G-G-Y-I-I-G-V-A-V-A-L-F-A-D-M-P-M-L-S-P-L-W-R-L-L-I-I-T-G-F-C-G-G-L-T-T-F-S-T-F-S-A-E-V-V-D-L-L-R-Q-G-Q-L-Q-P-A-F-A-A-I-A-V-H-V-S-G-S-L-L-M-T-M-A-G-I-A-S-W-Q-W-L-R-R


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-E-D-M-I-E-L-E-G-V-V-I-E-M-L-P-E-S-R-F-R-V-R-L-D-N-N-M-E-I-L-A-Y-G-S-G-K-M-K-M-H-R-I-R-V-L-L-G-D-R-V-T-V-E-M-S-P-Y-D-L-T-K-G-R-I-N-F-R-H-P-T-A-N-P-G-A-G-P-R-P-S-H-H-H-R-R


### FUNCTION Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide ### SEQUENCE -M-Q-S-Q-C-Q-P-A-P-R-Q-A-L-T-D-A-V-I-A-A-K-A-R-K-R-L-S-F-E-D-I-N-Q-G-T-G-L-S-L-A-Y-T-T-A-A-L-L-G-Q-H-A-L-P-E-A-A-A-R-L-V-A-E-R-L-E-L-D-E-D-A-I-A-L-L-Q-A-I-P-L-R-G-S-I-P-G-G-V-P-T-D-P-T-I-Y-R-F-Y-E-M-V-Q-I-Y-G-T-T-L-K-A-L-V-H-E-Q-F-G-D-G-I-I-S-A-I-N-F-K-L-D-I-R-K-V-E-D-P-D-G-G-H-R-A-V-I-T-L-D-G-K-Y-L-P-T-K-P-F


### FUNCTION Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate ### SEQUENCE -M-A-D-K-T-G-T-L-W-Y-V-M-G-P-S-G-A-G-K-D-S-L-L-A-Y-A-R-Q-R-L-P-G-G-V-M-F-A-H-R-Y-I-T-R-P-A-D-A-G-G-E-N-H-V-A-L-S-R-E-E-F-D-A-R-E-A-G-G-C-F-A-L-V-W-R-R-H-G-L-A-Y-G-L-G-V-E-T-E-L-W-L-G-Q-G-M-D-V-V-V-N-G-S-R-S-S-L-P-L-A-M-A-R-F-P-T-L-R-P-L-W-I-T-A-S-P-E-V-L-A-V-R-L-R-Q-R-A-R-E-C-G-E-V-I-E-R-R-L-A-E-A-A-S-F-A-P-P-A-G-C-E-V-L-V-N-D-G-A-L-A-Q-A-G-D-T-L-L-R-W-L-R-G-G-R-R-V-C


### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-N-D-I-H-P-N-Y-K-E-L-S-V-T-C-S-C-G-Q-Q-F-V-T-K-S-T-M-G-K-D-A-F-S-I-E-V-C-S-S-C-H-P-F-Y-T-G-K-Q-K-I-V-D-T-A-G-R-V-D-K-F-N-Q-K-F-G-S-F-F-K-R


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-Q-F-R-G-N-V-M-Q-E-N-Q-N-Q-A-A-E-A-V-E-N-E-M-T-E-T-A-S-A-A-H-T-E-L-E-Q-T-P-E-Q-R-I-A-G-L-E-A-E-I-A-E-L-N-D-T-L-L-R-A-R-A-E-L-E-N-Q-R-R-R-A-Q-D-E-V-A-A-A-H-K-Y-A-I-G-K-F-A-A-E-L-V-T-V-K-D-Y-L-E-M-A-L-L-D-Q-S-G-Q-I-D-A-L-K-M-G-V-D-M-T-L-K-Q-L-V-S-A-F-D-K-A-Q-I-K-D-I-A-P-K-L-G-D-K-L-D-P-H-Q-H-Q-A-M-S-A-E-E-S-D-A-E-P-N-T-V-V-R-V-M-Q-K-G-Y-L-L-A-D-R-V-L-R-P-A-M-V-V-V-A-K-A-K-A


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-K-N-P-P-A-L-E-Q-L-I-S-A-L-K-V-L-P-G-V-G-P-K-T-A-Q-R-M-A-F-H-L-L-Q-R-D-K-Q-G-A-D-K-L-A-R-A-L-D-R-A-L-T-Q-L-T-H-C-Q-R-C-N-T-F-S-E-A-E-L-C-A-I-C-A-D-E-T-R-R-R-D-Q-L-C-I-V-E-M-P-A-D-L-M-M-L-E-Q-A-K-C-F-D-G-L-Y-F-V-L-M-G-R-I-S-P-L-D-N-I-G-P-K-D-L-H-L-D-K-L-L-A-R-A-L-D-G-Q-V-S-E-I-V-I-A-T-N-F-T-A-E-G-E-V-T-S-H-M-L-S-E-L-F-K-E-R-G-L-T-V-T-R-I-A-R-G-M-P-V-G-G-E-L-E-Y-V-D-L-G-T-L-A-Q-A-V-Y-E-R-R-G-V


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-A-G-I-A-G-L-M-K-Q-A-Q-Q-M-Q-E-N-M-K-K-A-Q-E-E-L-A-K-V-E-V-E-G-Q-S-G-A-G-M-V-K-V-T-M-T-C-S-H-D-V-K-R-V-A-I-D-D-S-V-L-E-D-A-K-E-D-K-E-M-L-E-D-L-I-A-A-A-F-N-D-A-V-R-K-V-E-A-T-T-Q-E-R-M-S-G-F-T-N-G-L-N-L-P-A-G-M-K-F-P-F


### FUNCTION Modulates RecA activity ### SEQUENCE -M-A-A-E-G-K-S-L-K-A-R-A-A-E-L-L-S-R-R-E-Y-T-R-Q-E-L-V-R-R-L-A-P-F-A-D-S-E-D-E-L-N-A-A-L-D-E-L-A-A-S-N-W-Q-S-D-D-R-F-A-R-Q-F-A-S-S-K-G-T-K-F-G-S-R-R-L-A-Q-E-M-R-Q-R-G-V-D-S-D-T-I-R-E-A-L-S-G-Q-D-D-L-A-S-A-R-E-Q-W-R-K-K-F-G-R-L-P-A-D-A-A-E-K-A-R-Q-Y-R-F-L-A-Q-R-G-F-P-A-D-V-I-R-Q-V-L-A-G-G-A-D-D-D-F-Y-E-D


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-M-T-A-A-Q-K-A-E-I-V-K-G-F-Q-R-A-E-G-D-T-G-S-S-E-V-Q-I-A-L-L-T-A-R-I-N-D-L-T-P-H-F-K-A-N-T-K-D-H-H-S-R-R-G-L-L-K-L-V-S-R-R-R-R-L-L-D-Y-L-K-R-T-D-A-E-G-Y-R-A-L-I-T-R-L-G-L-R-K


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-A-K-K-G-F-S-R-S-D-R-V-A-E-Q-I-Q-R-E-L-A-E-L-T-R-K-G-L-K-D-P-R-A-G-W-I-T-I-T-A-V-E-V-T-R-D-Y-S-H-A-K-V-Y-Y-T-V-M-V-D-S-T-R-E-A-T-Q-E-A-L-D-S-S-A-G-Y-L-R-N-E-L-G-R-A-I-K-M-F-S-M-P-Q-L-H-F-V-Y-D-D-S-V-E-R-G-M-H-L-T-S-L-I-N-Q-V-A-R-E-D-A-E-K-F-G-E-A-A-A-G-E-A-E-G-E-G-K-A-E


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-D-V-R-L-L-L-E-N-T-L-P-G-L-G-Y-E-L-V-D-F-E-M-T-P-G-G-G-F-R-V-F-I-D-K-P-G-G-I-T-V-E-D-C-V-L-V-S-N-H-F-T-R-L-F-M-V-E-N-V-D-Y-E-R-L-E-V-S-S-P-G-L-D-R-P-L-K-K-E-A-D-F-V-R-F-S-G-Q-L-A-K-I-K-T-R-M-P-I-E-Q-Q-K-K-F-T-G-R-L-A-G-V-E-D-G-S-V-K-L-D-V-D-G-R-I-V-E-I-P-F-A-N-I-D-K-A-R-L-E-P-E-F


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-T-A-Q-E-L-R-A-G-N-V-F-M-V-G-S-D-P-M-V-V-Q-K-A-E-F-S-K-S-G-R-N-A-S-V-V-K-M-K-M-K-N-L-L-T-G-A-G-S-E-A-V-Y-R-A-D-D-K-F-D-V-V-V-L-D-R-K-D-C-T-Y-S-Y-F-A-D-P-M-Y-V-F-M-D-T-E-F-N-Q-Y-E-V-E-A-D-N-L-G-D-T-I-N-Y-I-V-D-G-M-E-D-V-C-Q-V-T-F-Y-D-G-K-A-I-S-V-E-L-P-T-T-V-I-R-E-V-E-Y-T-E-P-A-V-R-G-D-T-S-G-K-V-L-K-P-A-R-L-V-G-T-T-F-E-V-Q-V-P-A-F-V-N-T-G-E-K-I-E-I-D-T-R-T-N-E-F-K-K-R-A


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-V-L-K-E-F-K-E-F-A-V-K-G-N-V-I-D-L-A-V-G-V-V-I-G-G-A-F-G-S-I-V-K-S-L-V-D-D-V-I-M-P-P-I-G-L-L-I-G-N-V-D-F-S-N-L-F-F-V-L-K-D-G-A-K-Q-A-G-P-Y-V-S-V-A-A-A-K-Q-A-G-A-T-T-L-N-L-G-L-F-I-N-A-L-V-S-F-T-I-V-A-F-A-I-F-M-L-V-K-A-I-N-R-L-K-R-E-E-A-A-P-A-P-A-A-P-A-T-K-E-C-R-Y-C-L-S-A-I-P-E-K-A-T-R-C-P-C-C-T-S-Q-L-D


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-L-T-K-A-E-L-A-D-L-L-F-D-Q-V-G-L-N-K-R-E-A-K-D-M-V-E-S-F-F-E-E-I-R-L-A-L-E-S-G-D-S-V-K-L-S-G-F-G-N-F-Q-L-R-D-K-P-Q-R-P-G-R-N-P-K-T-G-E-E-I-P-I-T-A-R-R-V-V-T-F-H-A-S-Q-K-L-K-G-M-V-E-Q-Y-H-A-N-K-Q-G


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-R-A-R-H-K-K-I-L-A-L-A-K-G-Y-R-G-R-R-K-N-V-Y-R-I-A-K-Q-A-V-M-K-A-G-Q-Y-A-Y-R-D-R-R-Q-K-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-A-R-E-N-G-L-P-Y-S-K-F-M-N-G-L-K-K-A-A-I-E-I-D-R-K-V-L-A-D-L-A-V-F-D-K-P-A-F-A-Q-I-V-E-K-A-K-A-S-L-A-A


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-A-I-A-Q-E-R-E-A-R-I-N-G-E-I-T-A-R-E-I-R-L-V-G-K-E-G-E-Q-I-G-I-V-S-L-R-E-A-M-A-L-A-E-E-N-D-V-D-L-V-E-I-S-P-T-A-Q-P-P-V-C-K-L-M-D-Y-G-K-Y-K-Y-E-Q-S-K-K-R-H-E-A-K-Q-K-Q-K-Q-V-Q-I-K-E-I-K-F-R-P-G-T-D-D-G-D-Y-N-V-K-L-R-N-L-V-R-F-L-T-E-G-D-K-A-K-V-T-L-R-F-R-G-R-E-M-A-H-Q-D-I-G-L-A-L-L-K-R-V-E-A-D-L-A-E-V-G-T-V-E-Q-F-P-R-L-E-G-R-Q-M-V-M-M-I-A-P-K-K-K


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-A-F-C-G-N-P-D-T-Q-V-I-D-S-R-V-S-E-D-G-S-S-I-R-R-R-R-R-C-P-A-C-D-K-R-F-T-T-F-E-T-A-D-V-R-M-P-Q-V-V-K-T-A-G-H-R-S-E-F-D-I-E-K-V-R-T-S-F-L-R-A-L-H-K-R-P-V-S-T-T-L-V-D-E-A-I-D-R-I-C-H-K-L-L-Q-L-G-E-R-E-V-S-S-R-Q-I-G-E-M-V-M-N-E-L-A-R-L-D-K-V-A-Y-V-R-F-A-S-V-Y-R-S-F-Q-D-I-S-E-F-T-D-A-I-K-E-I-Q-K-S-S-H


### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-E-Q-Q-E-L-Q-P-A-F-S-I-E-K-I-Y-V-K-D-I-S-L-E-V-P-N-A-P-Q-V-F-L-E-Q-A-Q-P-E-I-D-M-Q-L-A-S-A-G-Q-Q-L-D-D-G-F-F-E-V-T-L-T-V-T-V-T-A-K-L-P-E-K-T-M-F-L-C-E-V-A-Q-A-G-I-F-Q-I-R-N-I-P-G-E-D-L-D-P-I-L-G-V-A-C-P-N-I-L-F-P-Y-A-R-E-T-V-S-S-V-V-N-R-A-G-F-P-P-V-L-L-A-P-I-N-F-E-A-L-Y-M-Q-Q-R-A-Q-Q-A-E-A-G-N-A


### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-L-D-R-D-G-Y-R-P-N-V-G-I-I-L-T-N-A-K-N-E-V-F-W-G-K-R-V-R-E-H-S-W-Q-F-P-Q-G-G-I-K-P-G-E-S-P-E-A-A-M-Y-R-E-L-L-E-E-V-G-L-L-P-Q-H-V-K-I-L-G-R-T-R-D-W-L-R-Y-E-V-P-T-N-W-V-R-R-E-W-R-G-S-Y-K-G-Q-K-Q-I-W-F-L-L-R-L-V-G-R-D-S-D-V-C-L-R-A-T-N-H-P-E-F-D-G-W-R-W-N-D-Y-W-A-P-V-D-A-V-I-E-F-K-R-D-V-Y-E-R-A-L-S-E-L-A-R-F-M-R-G-V-E-S-H-H-A-Y-L-A-R-T-S-T-Q-S-E-Q


### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-H-D-F-N-Q-D-F-F-S-L-F-G-L-P-R-R-F-A-I-D-A-A-G-L-D-A-A-W-R-A-A-A-A-Q-V-H-P-D-R-Y-A-A-S-S-D-A-D-K-R-S-A-L-M-L-A-T-R-V-N-E-G-Y-Q-T-L-K-S-P-L-N-R-A-R-Y-L-L-Q-L-S-G-V-D-T-Q-E-E-N-N-T-R-M-P-A-D-F-L-M-A-Q-M-E-W-R-E-S-I-D-D-A-R-A-D-V-D-A-L-E-S-L-S-R-R-L-R-G-E-V-R-D-L-Q-T-E-L-E-A-A-L-D-A-R-A-D-L-D-A-A-A-V-L-V-R-K-L-R-F-M-E-K-L-D-Q-E-I-G-D-A-I-E-S-L-L-D


### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-P-H-T-P-P-A-Y-P-A-A-S-A-D-H-R-P-P-S-S-P-P-A-E-P-A-G-E-A-V-F-L-H-P-G-D-W-H-F-G-D-S-Q-T-R-I-R-T-L-L-G-S-C-V-S-I-T-L-W-H-P-Q-A-K-V-G-G-M-C-H-Y-L-L-A-Q-R-T-P-H-R-G-E-S-L-S-G-R-Y-G-D-E-A-M-L-L-L-L-R-E-I-L-D-T-G-L-P-L-Q-E-F-Q-A-R-L-I-G-G-A-S-M-L-L-S-R-E-R-K-L-S-H-D-V-P-S-R-N-I-Q-Q-A-R-L-M-V-K-Q-L-G-L-K-L-L-A-E-D-L-G-G-N-C-P-R-M-V-L-F-D-V-A-S-G-N-V-W-I-K-Q-S-Q-E-A-E-L-E-Q-A-P-H-T-R-T-R-K


### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur , and thus conserves the redox energy in a proton gradient ### SEQUENCE -M-A-S-K-K-M-E-A-L-G-S-V-V-A-E-A-L-G-D-K-L-V-R-S-T-L-A-L-D-E-L-T-I-V-C-K-A-S-D-L-L-S-V-A-Q-T-L-R-D-H-A-D-L-A-F-E-Q-C-I-D-V-C-G-M-D-Y-S-A-Y-R-D-E-P-W-D-G-P-R-F-A-A-V-Y-H-L-L-S-V-K-L-N-H-R-I-R-L-R-V-F-A-E-D-D-D-F-P-V-I-P-S-V-N-G-I-W-N-A-A-N-W-F-E-R-E-A-F-D-L-Y-G-I-V-F-E-G-H-P-D-L-R-R-L-L-T-D-Y-G-F-V-G-H-P-F-R-K-D-F-P-L-S-G-Y-V-E-M-R-Y-D-P-T-Q-Q-R-V-I-Y-Q-P-V-T-I-E-P-R-E-I-T-P-R-I-I-R-E-E-N-Y-G-G


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-K-T-G-G-K-Q-Y-K-V-A-I-G-E-K-L-K-V-E-Q-I-P-A-D-V-D-S-Q-I-V-L-E-E-V-L-M-I-A-D-G-E-Q-V-V-V-G-A-P-L-V-S-G-A-T-V-K-A-T-V-V-S-H-G-R-G-E-K-I-R-I-F-K-M-R-R-R-K-H-Y-Q-K-H-Q-G-H-R-Q-N-Y-T-E-I-R-I-D-A-I-S-K


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-K-M-R-V-E-V-V-S-T-E-Q-L-I-F-S-G-E-A-E-F-V-V-A-P-A-T-E-G-E-I-G-V-Y-P-Q-H-V-P-L-L-T-R-I-K-P-G-V-L-R-L-K-V-P-G-T-K-E-E-V-L-V-A-V-S-G-G-M-M-E-V-Q-P-S-L-I-T-V-L-A-D-T-A-I-R-G-E-D-L-D-E-A-R-A-N-E-A-K-R-A-A-E-D-A-L-K-H-A-T-D-D-M-S-T-A-K-A-H-A-A-L-A-V-A-I-A-E-L-K-T-L-D-Y-L-K-K-R-A-H


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-L-I-T-V-A-R-P-Y-A-E-A-V-Y-S-L-A-T-E-Q-G-K-L-D-Q-W-S-D-A-L-S-W-L-A-A-M-V-N-N-P-D-L-A-Q-V-V-T-N-P-K-H-T-A-Q-E-V-E-A-L-M-L-D-V-L-G-S-R-G-N-D-D-V-K-R-F-I-A-A-L-I-E-N-A-R-L-T-L-L-P-E-I-A-A-Q-F-E-L-L-K-A-Q-S-E-N-I-V-D-A-L-V-E-S-A-F-A-L-S-D-E-Q-K-A-E-L-T-N-T-L-S-K-K-Y-G-K-A-V-R-L-D-V-R-E-N-A-D-L-I-G-G-V-R-V-S-V-G-D-D-V-I-D-A-S-V-R-G-K-L-Q-A-M-A-A-S-L-K-N


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-L-S-I-W-H-W-L-I-V-L-L-I-V-V-L-V-F-G-T-K-K-L-P-G-I-G-K-D-L-G-N-A-V-K-G-F-K-E-G-M-N-E-G-A-K-D-G-Q-P-P-A-K-D-A-G-R-I-I-D-G-E-A-D-K-K


### FUNCTION Functions as a ribosomal silencing factor Interacts with ribosomal protein uL14 , blocking formation of intersubunit bridge B8 Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation ### SEQUENCE -M-E-I-Q-E-I-S-K-L-A-I-E-A-L-E-D-I-K-G-K-D-I-I-E-L-D-T-S-K-L-T-S-L-F-Q-R-M-I-V-A-T-G-D-S-N-R-Q-V-K-A-L-A-N-S-V-Q-V-K-L-K-E-A-G-V-D-I-V-G-S-E-G-H-E-S-G-E-W-V-L-V-D-A-G-D-V-V-V-H-V-M-L-P-A-V-R-D-Y-Y-D-I-E-A-L-W-G-G-Q-K-P-S-F-A-V-G-A-A-K-P-W-S-A-V


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-K-I-T-I-L-A-V-G-T-K-M-P-R-W-V-D-E-A-Y-T-D-Y-A-K-R-F-G-R-D-I-T-L-E-L-K-E-I-K-P-E-K-R-G-G-G-V-T-A-E-K-G-I-A-A-E-H-E-R-L-I-A-A-I-P-P-R-A-R-L-V-V-M-D-E-R-G-K-N-W-T-S-V-K-L-A-E-G-L-K-E-W-M-A-G-G-G-D-V-V-F-V-I-G-G-A-D-G-L-S-A-E-L-K-Q-R-A-D-V-L-L-Q-L-S-A-M-T-L-P-H-G-M-V-R-V-M-L-A-E-Q-I-Y-R-A-Y-S-I-L-N-N-H-P-Y-H-R-E


### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-Q-Y-T-R-T-V-E-A-L-K-Q-G-T-V-I-D-H-I-P-A-G-E-G-V-K-I-L-R-L-F-K-L-T-E-T-G-E-R-V-T-V-G-L-N-L-V-S-R-H-M-G-S-K-D-L-I-K-V-E-N-V-A-L-T-E-E-Q-A-N-E-L-A-L-F-A-P-K-A-T-V-N-V-I-D-N-F-E-V-V-K-K-H-K-L-T-L-P-D-A-V-E-G-I-F-S-C-P-N-S-N-C-I-S-H-N-E-P-V-K-S-V-F-Y-V-K-T-L-A-H-D-T-K-M-K-C-K-Y-C-E-K-V-F-S-R-D-I-V-A-E-V-R


### FUNCTION Involved in iron-sulfur  cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-T-E-S-E-F-L-Q-L-S-D-D-I-F-D-R-I-E-Q-A-I-D-E-H-G-L-D-A-D-T-L-R-Q-G-N-V-L-E-I-E-F-D-S-G-D-K-V-I-V-N-R-H-A-V-N-Q-E-M-W-I-A-A-K-S-G-G-Y-H-F-S-R-R-G-E-A-W-I-A-S-R-D-G-A-E-F-Y-A-T-L-A-E-A-I-R-A-G-S-G-E-A-F-D-F-A-G


### FUNCTION Putative transcription factor May function redundantly with odd and sob in leg joint formation during the larval stages, acting downstream of Notch activation ### SEQUENCE -M-F-A-V-M-R-I-D-N-D-D-R-R-A-D-F-R-R-K-M-R-P-K-C-E-F-V-C-K-Y-C-Q-R-R-F-T-K-P-Y-N-L-M-I-H-E-R-T-H-K-S-P-E-V-T-F-S-C-E-V-C-G-K-Y-F-K-R-Q-D-N-L-R-S-H-R-C-S-Q-C-I-W-R


### FUNCTION E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage ### SEQUENCE -M-V-D-D-G-T-R-K-A-L-S-G-I-P-L-L-K-T-K-A-G-P-R-D-K-E-L-W-V-Q-R-L-K-E-E-Y-Q-A-L-I-K-Y-V-Q-N-N-K-A-S-D-M-D-W-F-R-L-E-S-N-K-E-G-T-K-W-F-G-K-C-W-Y-M-Y-N-L-H-K-Y-E-F-D-V-E-F-D-I-P-I-T-Y-P-T-T-S-P-E-I-A-L-P-E-L-D-G-K-T-A-K-M-Y-R-G-G-K-I-C-L-T-D-H-F-K-P-L-W-A-R-N-V-P-K-F-G-I-A-H-A-M-A-L-G-L-A-P-W-L-A-V-E-V-P-D-L-I-E-K-G-V-I-S-Y-Q-E-K-G-S-S


### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-A-D-R-L-T-Q-L-Q-D-T-V-N-Q-Q-A-E-H-F-C-N-S-I-G-I-L-Q-Q-C-S-V-P-S-K-F-A-G-F-E-R-T-G-S-Q-T-P-Q-Q-Q-V-H-Q-Q-Q-Q-L-P-Q-Q-Q-Q-Q-Q-Q-Q-P-Q-Q-Q-E-D-F-P-Q-L-F-S-T-L-I-S-R-C-A-K-D-I-D-T-L-I-E-S-L-P-S-E-E-S-S-I-E-L-Q-V-Q-S-L-Q-R-L-E-A-E-N-K-E-S-A-E-K-L-E-E-I-V-R-K-G-E-L-L-L-E-K-I-Q-A-A-L-S-D-I-A-Q-S-Q-L-D-M-Q-Y-S-S


### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs Pol II is the central component of the basal RNA polymerase II transcription machinery It is composed of mobile elements that move relative to each other RPB11 is part of the core element with the central large cleft ### SEQUENCE -M-N-A-P-P-T-F-E-S-F-L-L-Y-E-G-E-K-K-I-I-K-E-L-D-M-K-V-P-N-A-A-I-F-T-V-N-K-E-D-H-T-L-G-N-M-I-R-N-Q-L-L-K-D-P-N-V-L-F-A-G-Y-K-L-P-H-P-L-E-H-K-F-V-L-R-I-Q-T-T-S-E-Y-S-P-H-E-A-F-M-N-A-I-T-D-L-L-S-E-L-S-L-F-E-E-R-F-R-E-A-M-K-E-K-K-E-G-G-D


### FUNCTION Ubiquitin-like modifier protein which binds to a number of as yet unidentified target proteins ### SEQUENCE -M-A-A-S-K-V-T-F-K-I-T-L-T-S-D-P-K-L-P-F-K-V-L-S-V-P-E-A-T-P-F-T-A-V-L-K-F-A-A-E-E-F-K-V-P-P-A-T-S-A-I-I-T-D-D-G-I-G-I-N-P-Q-Q-T-A-G-T-V-F-L-K-H-G-S-E-L-R-L-I-P-R-D-R-V-G-C-R-C


### FUNCTION Component of the transcription regulatory histone acetylation  complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription ### SEQUENCE -M-S-E-N-D-G-I-H-I-E-Y-V-D-E-Q-E-L-K-R-E-F-R-R-F-M-S-D-P-E-T-R-E-K-A-A-N-Y-L-Y-E-S-L-V-D-E-T-I-L-G-I-A-Y-E-V-H-H-A-N-K-T-G-S-G-A-A-V-E-G-E-P-E-D-S-K-P-Y-T-I-V-D-Q-P-D-T-D-V-F-G-S-S-N-T-K-K-A-I-D-C-H-C-P-N-C-N-R-I-V-A-A-S-R-F-A-P-H-L-E-K-C-M-G-M-G-R-N-S-S-R-I-A-S-R-R-I-A-N-T-R-D-V-G-T-G-N-Y-F-G-G-D-E-D-D-E-D-D-A-D-W-S-G-E-K-R-K-K-K-I-S-Q-V-R-T-N-G-S-K-K-N-G-K-T-S


### FUNCTION Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA Stimulates commitment or early  complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region ### SEQUENCE -M-P-K-Y-Y-C-D-Y-C-D-T-Y-L-T-H-D-S-P-S-V-R-K-T-H-C-T-G-R-K-H-K-D-N-V-K-F-Y-Y-Q-K-W-M-E-E-Q-A-Q-H-L-I-D-A-T-T-A-A-Y-K-A-G-K-I-A-P-N-P-F-T-A-G-P-P-K-P-N-I-S-I-P-P-P-T-M-N-M-P-P-R-P-G-M-I-P-G-M-P-A-G-A-P-P-L-L-M-G-P-N-G-P-L-P-P-P-M-M-G-M-R-P-P-P-M-M-V-P-T-M-G-M-P-P-M-G-L-G-M-R-P-P-V-M-S-A-A-P-P-Q-L-N-P-K-S


### FUNCTION Required for the function of the class 1 Sin3-histone deacetylase complex ### SEQUENCE -M-M-N-N-N-G-F-S-T-G-E-E-D-S-R-G-P-A-D-Q-I-C-C-L-L-D-D-G-E-R-C-R-K-Q-A-G-N-A-S-Y-S-K-R-I-Q-K-T-V-T-Q-R-R-L-K-L-S-I-D-S-H-A-R-H-I-Y-I-C-D-F-H-K-A-R-I-Q-C-A-R-T-K-R-R-R-R-D-S-E-D-D-S-N-E-T-D-T-D-L-P-E-V-D-L-Y-Q-L-Q-V-N-T-L-R-R-Y-K-R-F-Y-K-V-S-T-R-P-S-S-N-K-A-Q-L-S-E-T-I-M-K-H-F-K-T-I-P-I-K-E-K-E-I-L-T-Y-F-I-Y-M-V-K-S-N-S-N-K-L-D-Q-K-N-N-A-S-A-E-A-T


### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-R-R-Q-Y-S-M-W-A-S-T-V-A-V-I-A-C-G-S-A-L-M-L-L-H-P-V-G-A-D-A-P-K-K-R-C-L-T-K-P-N-V-S-K-K-V-D-M-V-I-H-Q-C-Q-E-E-I-K-S-S-L-I-E-D-A-L-K-I-F-T-A-E-H-G-Q-W-H-D-R-R-K-R-D-E-G-G-L-D-F-S-H-P-T-I-V-S-H-E-D-K-W-I-A-G-C-L-M-Q-C-V-Y-R-K-N-N-A-I-D-K-N-G-W-P-T-L-D-G-L-V-S-L-Y-T-D-G-V-N-E-Q-G-Y-F-M-A-T-L-R-G-V-D-R-C-L-K-G-T-S-K-K-Y-Q-I-K-R-N-D-A-A-E-N-F-E-Q-C-E-V-A-F-D-V-F-D-C-I-S-D-M-I-T-D-Y-C-S-G-Q-M-E-D-D-H


### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-T-S-P-L-E-N-L-E-N-H-L-E-M-F-I-E-N-V-R-Q-I-R-I-I-V-S-D-F-Q-P-Q-G-Q-N-V-L-N-Q-K-I-Q-S-L-V-T-G-L-Q-E-I-D-K-L-K-N-Q-I-D-V-N-V-P-L-E-V-F-D-Y-I-D-Q-G-R-N-P-Q-L-Y-T-K-D-C-I-D-K-A-L-T-K-N-E-E-V-K-G-K-I-D-S-Y-R-K-F-K-S-N-L-M-K-E-L-S-E-T-F-P-V-E-I-S-K-Y-K-A-I-R-G-D-E


### FUNCTION Acts as a sulfur carrier required for 2-thiolation of mcm that is covalently conjugated via an isopeptide bond to lysine residues of target proteins The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates ### SEQUENCE -M-D-D-S-I-D-E-E-V-I-S-G-G-S-T-I-T-V-E-F-S-G-G-A-E-T-L-F-G-G-V-K-E-H-I-V-P-L-D-G-S-K-I-V-L-L-E-E-M-L-R-W-L-R-D-H-L-L-T-G-D-A-G-L-F-L-Q-E-N-T-V-R-P-G-I-L-V-M-I-N-D-T-D-W-D-L-M-G-E-T-E-Y-I-L-Q-P-G-D-H-I-L-F-I-S-T-L-H-G-G


### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-Q-R-N-L-T-Q-S-K-E-A-L-L-K-S-Y-N-S-R-L-K-E-D-I-R-S-M-R-E-N-F-E-E-I-I-R-L-A-K-G-E-N-D-T-Q-L-S-K-I-T-Q-C-E-Q-D-T-Y-E-T-Q-V-R-A-A-N-I-V-R-A-G-E-S-L-M-K-L-V-S-D-I-K-Q-Y-L-I-L-N-D-F-H-S-V-N-E-A-I-C-S-N-S-T-L-Y-R-T-T-Q-I-D-R-D-N-K-L-M-A-V-R-D-D-M-A-A-D-L-Y-D-L-E-E-E-Y-Y-T-S-I-Y-K


### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-K-I-W-K-D-V-F-T-G-D-E-M-F-S-D-T-Y-K-V-K-L-V-D-D-V-M-Y-E-V-Y-G-K-H-V-S-R-T-L-G-D-V-Q-L-D-G-A-N-P-S-A-E-E-A-E-E-G-T-E-S-A-T-E-S-G-V-D-I-V-L-N-H-R-L-V-E-T-G-F-S-D-K-K-Q-F-T-T-Y-L-K-D-Y-M-K-K-L-V-T-R-L-E-E-K-S-P-G-E-V-E-V-F-K-T-N-I-N-K-V-M-K-D-L-L-G-R-F-K-D-L-Q-F-F-T-G-E-S-M-D-C-E-G-L-I-A-M-L-E-Y-R-D-I-D-G-E-S-V-P-V-L-L-C-F-K-H-G-L-E-E-E-K-F


### FUNCTION Essential regulatory subunit of the mitochondrial calcium uniporter  channel, a protein that mediates calcium uptake into mitochondria ### SEQUENCE -M-V-L-T-R-V-I-R-A-V-G-R-S-T-L-L-E-T-G-V-A-G-S-G-G-G-Q-L-Q-L-V-R-L-P-L-R-R-K-Y-T-Y-R-S-G-A-L-K-P-M-P-E-I-T-P-F-G-L-F-G-I-I-A-T-V-I-P-G-L-L-I-G-A-T-I-S-K-N-M-A-N-F-L-E-E-N-D-L-F-V-P-S-D-D-D-D-D-D-D


### FUNCTION GTP-binding protein involved in protein trafficking ### SEQUENCE -M-G-N-T-L-S-I-F-G-K-L-F-D-G-L-F-G-K-K-E-M-R-I-L-M-V-G-L-D-A-A-G-K-T-T-I-L-Y-K-L-K-L-G-E-V-V-T-T-I-P-T-I-G-F-N-V-E-T-V-E-Y-K-N-I-Q-F-T-V-W-D-V-G-G-Q-D-K-I-R-P-L-W-R-H-Y-F-Q-N-T-Q-G-I-I-F-V-V-D-S-N-D-R-D-R-V-V-E-A-R-E-E-L-Q-R-M-L-N-E-D-E-L-R-D-A-L-L-L-V-F-A-N-K-Q-D-L-P-N-A-M-N-A-A-E-I-T-D-K-L-G-L-S-S-L-R-Q-R-S-W-Y-I-Q-A-T-C-A-T-T-G-D-G-L-F-E-G-L-D-W-L-S-T-E-L-K-K-K-S-P


### FUNCTION Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner In the complex, it is required to stimulate activity of mtHSP70 ### SEQUENCE -M-S-S-A-V-A-I-G-A-G-V-A-V-A-A-F-L-G-R-A-G-L-V-A-W-R-R-S-R-G-G-V-G-A-L-G-K-A-F-Y-K-G-G-F-E-P-R-M-N-K-K-E-A-S-L-I-L-S-L-N-E-R-T-I-T-K-D-K-I-R-K-A-H-R-T-L-M-L-L-N-H-P-D-R-G-G-S-P-Y-L-A-T-K-V-N-E-A-K-E-F-L-E-K-S-V


### FUNCTION Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane ### SEQUENCE -M-S-D-S-T-S-S-P-V-A-A-A-P-S-T-A-M-T-R-P-V-S-E-A-L-L-N-E-K-W-D-R-C-L-S-N-L-L-I-K-S-T-L-G-L-G-F-G-V-V-F-S-V-L-I-F-K-R-R-A-W-P-A-F-V-G-V-G-F-G-A-G-R-A-Y-E-E-C-N-T-S-L-K-Q-A-A-R-E-I-R-A-Q-A


### FUNCTION Involved in protein synthesis Involved in microtubule stabilization ### SEQUENCE -M-L-I-Y-S-D-I-I-T-G-D-E-I-I-S-D-S-Y-D-L-K-E-V-D-G-I-A-Y-E-V-D-C-A-M-I-E-E-G-A-V-Q-V-D-I-G-A-N-A-S-A-E-E-A-D-E-A-L-D-D-G-V-V-K-V-N-N-V-V-H-S-F-R-L-Q-S-T-Q-F-D-K-K-G-Y-L-V-Y-L-K-G-Y-M-K-S-V-K-N-A-L-K-E-Q-G-K-S-D-E-E-I-K-D-F-E-T-K-A-S-A-F-A-K-N-V-I-L-A-K-F-K-D-W-E-F-Y-T-G-E-S-M-N-P-D-G-M-V-V-L-L-N-Y-R-E-D-G-T-T-P-Y-V-V-V-W-K-H-G-L-K-E-T-K-V


### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-G-K-D-K-K-A-S-G-S-G-S-G-S-K-G-G-K-D-A-G-N-K-D-A-G-K-D-A-G-K-A-S-K-G-A-Q-S-I-N-V-R-H-I-L-C-E-K-H-G-K-K-E-E-A-L-A-K-I-R-D-G-A-D-F-G-A-V-A-R-E-Y-S-E-D-K-A-R-T-G-G-S-L-G-W-K-Q-K-G-T-L-D-P-E-F-E-K-V-A-F-A-L-E-T-S-S-T-S-S-P-K-I-G-E-V-K-T-Q-F-G-Y-H-I-I-M-V-E-G-K-K


### FUNCTION Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol ### SEQUENCE -M-R-L-S-A-A-V-I-A-L-L-S-T-S-A-A-A-F-S-V-Y-R-E-N-S-V-S-A-N-D-E-L-D-V-P-G-K-S-P-L-R-F-C-D-A-A-A-D-R-K-D-D-I-V-T-I-E-E-V-I-L-T-P-N-P-P-E-A-G-Q-T-L-T-I-E-A-S-G-I-V-K-E-A-I-E-E-G-A-Y-V-N-L-Q-V-K-Y-G-Y-I-R-L-I-N-T-S-A-D-L-C-K-E-M-K-N-V-E-L-E-C-P-I-K-K-G-R-L-S-I-T-K-N-V-E-L-P-K-E-I-P-P-G-K-Y-T-V-E-A-D-V-Y-N-S-D-D-K-H-I-T-C-L-T-A-T-V-F-F-G-R-K-T-L-G-F-L-D-D-L


### FUNCTION DNA-binding protein that induces severe bending of DNA Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex ### SEQUENCE -M-P-K-A-A-A-K-S-K-T-T-G-K-V-E-K-R-R-A-K-K-D-P-N-A-P-K-R-G-L-S-A-Y-M-F-F-A-N-E-Q-R-E-N-V-R-E-E-N-P-G-V-S-F-G-Q-V-G-K-I-L-G-E-R-W-K-A-L-S-D-K-Q-R-A-P-Y-E-A-K-A-A-A-D-K-K-R-Y-E-D-E-K-Q-A-Y-N-A-E-A-D-E-E-E-S-S


### FUNCTION Required for the assembly of the V0 complex of the vacuolar ATPase  in the endoplasmic reticulum ### SEQUENCE -M-A-T-R-R-I-I-S-Q-E-K-T-L-L-E-K-D-D-R-I-G-S-S-P-A-A-S-E-K-S-N-I-T-P-A-V-P-A-S-V-I-I-K-L-L-A-F-T-F-A-M-I-V-I-P-I-S-S-Y-F-L-T-V-D-R-L-F-K-G-N-S-T-Y-A-G-A-T-A-A-I-M-A-N-V-V-L-I-G-Y-I-I-V-A-M-A-E-D-Q-S-D-Q-E-N-E-K-K-G-G-G-G-K-G-E-G-K-K-D-L


### FUNCTION Required for the assembly of cytochrome c oxidase ### SEQUENCE -M-A-Q-A-G-S-E-N-K-E-P-W-N-E-E-T-R-A-K-F-E-G-K-S-R-S-E-Y-L-D-P-C-Q-E-A-A-Q-R-S-I-R-C-L-H-R-N-Q-G-D-R-T-M-C-S-D-Y-F-E-A-Y-R-E-C-K-K-Q-W-I-E-R-R-R-E-Q-K-R-K-A-G-A-L-F


### FUNCTION Golgi membrane protein involved in vesicular trafficking ### SEQUENCE -M-A-L-K-D-E-F-A-T-R-N-F-S-I-Y-G-Q-W-L-G-I-L-S-M-I-L-C-F-A-L-G-I-A-N-I-F-T-F-R-P-I-I-I-V-F-S-V-I-T-L-C-F-S-F-V-I-L-F-V-E-V-P-L-L-L-R-I-C-P-T-S-P-T-F-D-N-L-I-R-K-I-S-T-N-Y-T-R-A-A-A-Y-G-V-M-A-V-V-V-F-L-S-C-I-D-R-T-T-S-L-L-V-P-G-I-F-L-S-F-T-G-I-C-Y-A-L-A-A-L-K-G-Q-A-F-V-G-S-K-T-L-G-G-A-G-V-A-Q-M-I-V


### FUNCTION Mannose-binding lectin ### SEQUENCE -M-S-F-H-V-T-A-E-D-A-R-I-E-V-R-D-N-R-T-I-L-F-A-R-L-R-R-E-D-G-E-W-N-D-A-S-Y-E-L-D-Q-I-I-G-N-N-D-G-H-F-Q-W-G-G-Q-N-F-T-E-T-A-E-D-I-R-F-H-P-K-E-G-A-A-E-Q-P-I-L-R-A-R-L-R-D-C-N-G-E-F-H-D-R-D-V-N-L-T-E-I-V-E-N-V-N-G-E-F-Q-A-K-F


### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-S-D-R-L-S-Q-L-Q-E-A-V-D-Q-L-M-E-Q-F-I-A-T-Y-F-Y-I-D-R-H-H-D-L-K-T-F-S-P-K-D-T-I-A-P-S-K-A-D-Q-P-P-E-V-D-T-L-P-P-D-V-F-Q-A-G-Q-L-E-L-A-R-D-L-I-T-R-E-Q-Q-I-E-Y-L-I-S-S-L-P-G-L-D-N-S-E-Q-D-Q-L-Q-S-I-K-E-L-E-E-E-L-N-V-A-E-K-Q-R-Q-E-A-V-K-E-K-D-E-V-L-V-K-L-D-Q-T-L-R-S-I-R-R-Y


### FUNCTION Has a role in mitochondrial fission Has a role in outer membrane fission but not matrix separation ### SEQUENCE -M-T-Q-L-P-Y-A-V-D-A-E-T-P-L-N-P-A-E-L-N-V-L-R-A-Q-Y-E-K-E-G-E-M-V-G-V-Q-T-K-F-N-Y-A-W-G-L-V-K-S-N-V-R-A-D-Q-H-L-G-V-M-L-L-S-E-I-F-R-T-S-P-E-R-R-R-E-C-L-Y-Y-L-A-L-G-N-Y-K-L-G-N-Y-A-Q-A-R-K-Y-N-D-A-L-L-E-N-E-P-A-N-L-Q-A-A-N-L-R-A-L-I-D-D-K-V-T-K-E-G-L-M-G-V-A-I-I-S-G-V-A-V-A-A-G-V-I-G-G-V-L-L-R-N-L-G-R-K-R


### FUNCTION Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis ### SEQUENCE -M-A-S-T-Q-P-K-N-D-A-K-S-T-E-P-K-P-E-Q-P-V-T-E-K-K-T-A-V-L-E-E-D-D-E-F-E-D-F-P-V-D-D-W-E-A-E-D-T-E-A-A-K-G-N-N-E-A-K-H-L-W-E-E-S-W-D-D-D-D-T-S-D-D-F-S-A-Q-L-K-E-E-L-K-K-V-E-A-A-K-K-R


### FUNCTION Component of the adaptor complexes which link clathrin to receptors in coated vesicles Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration ### SEQUENCE -M-L-S-F-I-L-I-Q-N-R-Q-G-K-T-R-L-A-K-W-Y-V-P-Y-S-D-E-E-K-I-K-L-K-G-E-I-H-R-L-V-A-P-R-D-Q-K-Y-Q-S-N-F-V-E-F-R-N-H-K-V-V-Y-R-R-Y-A-G-L-F-F-C-A-C-V-D-T-N-D-N-E-L-A-Y-L-E-A-I-H-F-F-V-E-V-L-D-S-F-F-G-N-V-C-E-L-D-L-V-F-N-F-Y-K-V-Y-A-I-L-D-E-V-F-L-A-G-E-I-E-E-T-S-K-Q-V-V-L-T-R-L-E-H-L-D-K-L-E


### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-A-P-A-A-S-G-A-K-K-Q-K-K-K-W-S-K-G-K-V-K-D-K-A-Q-H-A-V-I-L-D-K-S-T-S-D-K-L-Y-K-D-V-Q-S-Y-R-L-V-T-V-A-T-L-V-D-R-L-K-I-N-G-S-L-A-R-R-C-L-K-D-L-E-E-K-G-Q-I-K-Q-V-V-G-H-S-K-M-K-I-Y-T-R-A-I-G-A-D-E


### FUNCTION May be involved in cellular response to stress Required to maintain mitochondrial DNA ### SEQUENCE -M-L-S-W-Y-K-A-Q-L-A-A-R-P-L-L-T-Q-A-V-T-T-S-I-L-F-G-V-G-D-V-A-A-Q-Q-L-V-D-R-R-G-L-S-N-H-D-L-T-R-T-G-R-M-V-L-Y-G-G-A-V-F-G-P-A-A-T-T-W-F-R-F-L-Q-K-R-V-V-V-P-G-S-T-N-K-T-I-L-A-R-V-A-A-D-Q-G-L-F-A-P-T-F-I-G-I-F-L-G-S-M-A-V-L-E-G-T-D-V-K-E-K-L-Q-K-N-Y-W-E-A-L-S-T-N-W-M-V-W-P-F-V-Q-M-V-N-F-K-V-V-P-L-D-H-R-V-L-F-V-N-V-I-S-I-G-W-N-C-Y-L-S-W-L-N-G-Q


### FUNCTION Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit ### SEQUENCE -M-S-S-T-T-T-T-T-Q-T-T-S-Q-V-E-T-K-A-V-S-K-P-L-G-M-R-V-N-G-K-Q-W-H-A-P-K-K-A-F-R-P-G-S-G-L-T-S-Y-E-K-R-A-K-E-R-Q-L-L-A-A-V-K-A-K-E-K-E-L-K-D-E-K-E-A-E-R-K-R-R-I-E-A-L-K-E-K-R-A-K-K-E-E-K-E-R-Y-E-K-M-A-E-K-M-H-K-K-R-V-E-R-L-K-R-K-E-K-R-N-K-L-I-N-S


### FUNCTION Essential for the assembly of ubiquinol-cytochrome c reductase It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b ### SEQUENCE -M-A-A-K-K-P-V-N-W-W-L-W-T-K-M-L-L-G-G-A-A-I-C-V-G-G-P-A-F-T-Y-W-L-T-P-T-D-E-E-L-F-Q-K-Y-N-P-E-L-Q-K-R-S-L-E-R-R-F-E-R-Q-Q-E-F-D-D-F-V-T-K-L-K-E-Y-S-K-S-D-K-P-I-W-T-V-Q-A-E-A-E-E-K-E-R-Q-Q-R-A-S-V-Q-K-S-L-A-L-A-D-E-V-K-A-R-K-E-A-M-R-R-E-A-G-L-P-L-E-K


### FUNCTION Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A The NuA4 complex is also involved in DNA repair ### SEQUENCE -M-M-D-N-S-G-P-K-M-G-A-A-D-G-A-A-G-I-P-Y-Y-E-K-Q-R-Q-H-L-K-E-L-L-N-K-K-K-L-L-E-K-R-L-L-A-Q-E-E-S-I-Y-Q-K-E-T-E-Y-L-E-N-T-P-A-G-N-I-I-T-G-F-D-N-Y-T-K-G-T-A-N-V-A-A-Q-R-R-K-T-G-L-T-D-A-N-R-V-F-S-R-S-S-I-S-Y-N-P-A-A-Q-Q-D-S-Q-T-P-A-S-S-A-P-A-S-H-A-P-T-P-V-S-T-S-F-N-N-K-D-G-A-S-S-A-P-T-P-T-S-A-T-A-G-K-A-N-S-K-K-K-K-A-A-T-S-G-G-A-G-V-E-D-S-E-T-D-S-R-E-T-K-K-A-R-T-N-F-G-A-V-R-K


### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase  to ubiquinol Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants May act together with SDHAF1 ### SEQUENCE -M-Y-A-L-R-P-T-L-R-R-S-A-A-A-A-L-T-H-S-K-N-H-N-Y-G-M-T-P-G-P-L-A-L-L-P-P-I-Y-L-Y-R-R-L-L-R-A-H-R-K-Y-L-P-R-E-M-R-L-L-G-D-E-Y-V-K-A-E-F-R-A-H-R-S-V-D-N-P-A-H-L-I-G-F-L-T-E-W-Q-L-Y-A-Q-K-I-E-G-N-S-W-V-G-E-K-L-D-K-G-K-V-E-K-M-S-D-E-Q-I-G-Q-L-Y-E-L-M-Q-A-I-Q-K-R-G-T-E-G-D-L-E-D-G-D-G-G-E-S-G-Q-K-S-Q


### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-A-S-D-P-M-S-V-N-S-S-A-R-E-P-P-A-P-P-G-S-G-A-D-E-P-K-Y-G-G-Y-T-R-F-E-L-E-L-E-F-V-Q-A-L-G-N-P-L-Y-L-N-H-L-A-S-R-K-L-L-S-N-P-A-F-I-A-Y-L-D-Y-L-Q-Y-W-S-R-P-P-Y-L-K-Y-I-T-Y-P-G-P-T-L-K-N-L-E-L-L-Q-Q-E-K-F-R-Q-D-I-I-S-P-D-L-V-E-R-L-R-L-E-G-M-K-A-G-I-D-W-H-R-E-S-F-P-S-T-A


### FUNCTION Golgi membrane protein involved in vesicular trafficking ### SEQUENCE -M-M-E-A-T-P-T-P-G-S-L-S-W-R-L-S-S-H-P-I-T-L-L-T-F-L-A-F-R-S-S-S-L-L-V-Y-L-F-G-L-L-F-T-D-N-L-V-M-I-F-I-I-T-I-L-L-L-A-G-D-F-Y-Y-L-K-N-I-A-G-R-R-L-V-G-L-R-W-W-N-E-V-D-P-N-S-G-D-S-H-W-V-F-E-S-S-E-P-G-T-K-I-I-N-A-T-D-S-R-F-F-W-L-A-I-Y-A-Q-P-L-L-W-V-V-L-A-I-V-A-L-F-S-L-K-F-I-W-L-P-L-V-A-I-A-L-V-L-T-I-T-N-S-L-A-F-S-R-C-D-K-F-S-Q-A-S-N-I-A-G-T-A-F-S-S-G-N-I-A-G-N-I-A-S-N-M-V-G-R-F-F-S-R


### FUNCTION Highly reducing polyketide synthase ### SEQUENCE -M-A-P-P-N-K-N-P-N-G-Y-Y-V-E-S-F-P-A-P-G-L-R-Q-I-V-R-H-I-T-G-L-N-K-Q-G-E-S-V-F-L-H-S-D-H-G-D-H-H-R-F-M-V-Q-N-Q-A-I-S-N-L-L-Y-S-T-Q-E-T-P-V-D-L-N-N-N-I-D-I-Q-K-A-K-E-K-E-P-P-F-H-Y-K-S-G-S-I-V-R-M-I-D-F-G-P-G-V-E-S-P-L-H-R-A-M-T-I-D-Y-G-I-I-V-E-G-V-F-E-L-I-L-D-S-G-E-K-R-I-M-R-Q-G-D-V-S-V-Q-R-A-T-A-H-K-W-V-N-V-T-G-N-G-T-L-P-G-R-V-M-W-V-L-L-D-C-K-E-V-V-D-A-K-G-E-K-V-E-G-Y-L-G-S-L-Q-E-H-Y-E-G-R


### FUNCTION Required for the assembly of the mitochondrial respiratory chain complex IV , also known as cytochrome c oxidase May participate in merging the COX1 and COX2 assembly lines ### SEQUENCE -M-T-F-Q-S-K-K-F-P-S-T-A-N-T-N-T-F-A-A-K-Y-R-A-M-M-K-K-H-P-F-L-L-F-G-L-P-F-M-S-V-I-V-A-G-S-F-I-L-T-P-A-A-A-I-R-Y-E-K-Y-D-R-K-V-R-Q-V-S-R-E-E-E-L-G-L-G-Q-R-K-R-R-V-D-I-R-E-E-Y-Y-R-L-A-A-K-D-L-D-N-W-E-Q-K-R-V-E-R-L-K-G-E-S-D-G-L-L


### FUNCTION Mitochondrial membrane ATP synthase ### SEQUENCE -M-A-A-R-N-A-A-L-K-V-D-W-A-K-I-T-T-S-L-G-L-R-G-Q-T-A-A-S-L-Q-A-F-K-K-R-N-D-D-A-R-R-K-L-Q-Q-L-S-E-L-P-T-T-V-D-F-A-A-Y-R-S-T-L-K-N-Q-A-I-V-N-E-I-E-K-R-F-T-S-F-K-P-A-T-Y-D-V-N-R-Q-L-K-A-I-E-A-F-E-V-E-A-I-K-N-A-E-A-T-K-T-K-V-D-L-E-L-K-D-L-E-K-T-L-T-N-I-E-T-A-R-P-F-D-E-L-T-V-D-E-V-A-A-A-E-P-S-I-D-E-K-T-S-K-L-V-S-K-G-R-W-S-V-P-G-Y-K-E-R-F-G-D-L-S-V-L


### FUNCTION Involved in resistance toward heavy metals ### SEQUENCE -M-E-E-V-V-L-I-T-V-P-S-E-E-V-A-R-T-I-A-K-A-L-V-E-E-R-L-A-A-C-V-N-I-V-P-G-L-T-S-I-Y-R-W-Q-G-E-V-V-E-D-Q-E-L-L-L-L-V-K-T-T-T-H-A-F-P-K-L-K-E-R-V-K-A-L-H-P-Y-T-V-P-E-I-V-A-L-P-I-A-E-G-N-R-E-Y-L-D-W-L-R-E-N-T-G


### FUNCTION Transcriptional repressor Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CACTG-3' ### SEQUENCE -M-E-V-N-T-C-N-I-Q-V-L-L-Q-A-A-E-Y-L-E-R-R-E-R-E-A-E-H-G-Y-A-S-V-L-P-F-Y-S-N-G-V-S-D-K-R-K-K-Q-K-S-K-S-H-S-S-P-G-N-S-R-S-V-H-N-E-L-E-K-H-R-R-A-Q-L-R-H-C-L-E-Q-L-K-Q-Q-V-P-L-S-S-D-S-S-R-N-T-T-L-N-L-L-R-Q-A-Q-L-H-I-K-K-L-Q-E-Q-D-E-R-A-K-L-L-K-D-R-L-R-W-E-Q-R-E-L-R-T-R-L-E-K-L-Q-G-G-S-E-R-M-R-S-D-S-L-G-S-A-V-S-S-E-R-S-D-S-E-R-E-D-V-E-I-D-V-E-S-M-V-W-T-L-E-A-D-A-L-G-S-S-H-A-G-V-D-H-S-Y-S-T-S-D-H-A-W-L


### FUNCTION Stores iron in a soluble, non-toxic, readily available form Important for iron homeostasis Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation ### SEQUENCE -M-S-A-Q-S-Q-I-R-Q-N-Y-H-E-E-S-E-A-G-V-N-R-I-A-N-L-E-L-Q-A-S-Y-L-Y-L-S-V-G-Y-Y-F-D-R-D-D-V-A-L-S-K-F-S-K-F-F-R-E-L-S-E-K-K-R-D-H-A-E-D-F-L-K-F-Q-N-K-R-G-G-R-V-V-L-Q-D-V-K-K-P-D-D-D-E-W-G-N-G-T-K-A-M-E-V-A-L-N-L-E-K-S-I-N-Q-A-V-L-D-L-H-K-I-A-T-D-H-T-D-P-H-M-Q-D-Y-L-E-H-E-F-L-E-E-E-V-K-L-I-K-K-L-G-D-H-L-T-N-L-R-R-V-K-A-A-E-E-G-M-G-E-Y-L-F-D-K-L-T-L-G-E-D


### FUNCTION May play a role into cellular response to oxidative stress May decrease cell proliferation ### SEQUENCE -M-S-K-A-T-K-R-K-H-V-V-K-E-V-L-E-D-Y-V-T-P-T-E-D-Q-Q-I-M-R-V-L-G-S-N-G-N-N-L-H-E-A-V-T-G-S-G-E-R-F-L-L-S-M-P-T-K-F-R-K-N-I-W-I-K-R-G-D-F-V-I-V-D-P-I-K-E-G-G-K-V-K-G-E-I-S-F-I-L-Y-R-D-H-I-Q-H-L-R-K-L-G-V-W-P-E-G-F-Q-E-D-R-T-S-G-E-R-N-E-G-T-Q-K-E-R-S-E-E-K-E-E-E-E-G-D-S-E-S-E-D-D-D-S-D-L-F-V-N-T-N-R-A-T-V-L-Y-S-E-S-E-E-E-T-D-E-D-E-E-E-D-K-G-R-A


### FUNCTION May be involved in the calcium-dependent regulation of rhodopsin phosphorylation Binds three calcium ions ### SEQUENCE -M-G-K-Q-N-S-K-L-R-P-E-V-M-Q-D-L-L-E-S-T-D-F-T-E-H-E-I-Q-E-W-Y-K-G-F-L-R-D-C-P-S-G-N-L-T-M-E-E-F-K-K-I-Y-G-N-F-F-P-Y-G-D-A-S-K-F-A-E-H-V-F-R-T-F-D-A-N-G-D-G-T-I-D-F-R-E-F-I-I-A-L-S-V-T-S-R-G-K-L-E-Q-K-L-K-W-A-F-S-M-Y-D-L-D-G-N-G-Y-I-S-K-A-E-M-L-E-I-V-Q-A-I-Y-K-M-V-S-S-V-M-K-M-P-E-D-E-S-T-P-E-K-R-T-E-K-I-F-R-Q-M-D-T-N-R-D-G-K-L-S-L-E-E-F-I-R-G-A-K-S-D-P-S-I-V-R-L-L-Q-C-D-P-S-S-A-G-R-F


### FUNCTION Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction Covalent attachment to its substrates requires prior activation by the E1 complex sae1-sae2 and linkage to the E2 enzyme ube2i ### SEQUENCE -M-S-E-E-K-P-K-E-G-V-K-T-E-N-D-H-I-N-L-K-V-A-G-Q-D-G-S-V-V-Q-F-K-I-K-R-H-T-P-L-S-K-L-M-K-A-Y-C-D-R-Q-G-L-S-M-R-Q-I-R-F-R-F-D-G-Q-P-I-N-E-T-D-T-P-A-Q-L-E-M-E-D-E-D-T-I-D-V-F-Q-Q-Q-T-G-G-V-C


### FUNCTION May be involved in ciliary biogenesis or function ### SEQUENCE -M-A-D-V-V-L-G-V-G-T-G-V-F-I-I-T-L-I-W-I-L-T-L-A-L-T-I-I-L-S-R-A-T-G-P-T-K-L-G-I-I-P-V-V-L-L-A-L-I-I-T-L-V-L-V-F-F-P-R-A-A-E-V-P-A-P-Q-R-A-A-Q-I-V-D-M-F-F-I-G-R-Y-V-L-L-S-L-V-S-L-V-F-L-A-A-L-F-M-L-L-P-L-H-F-L-E-P-I-Y-A-K-P-L-R-T-H


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-K-R-T-K-K-V-G-I-V-G-K-Y-G-T-R-F-G-A-S-L-R-K-M-V-K-K-I-E-I-S-Q-H-A-K-Y-T-C-S-F-C-G-K-T-K-M-K-R-K-A-V-G-I-W-H-C-G-S-C-M-K-I-V-A-G-G-A-W-T-Y-N-T-T-S-A-V-T-V-K-S-A-I-R-R-L-K-E-L-K-D-Q


### FUNCTION Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum ### SEQUENCE -M-D-Q-I-M-Q-F-V-E-P-S-R-Q-F-V-K-D-S-I-R-L-V-K-R-C-T-K-P-D-R-K-E-F-Q-K-I-A-M-A-T-A-I-G-F-A-I-M-G-F-I-G-F-F-V-K-L-I-H-I-P-I-N-N-I-I-V-G-G


### FUNCTION Anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factor IX  in the presence of calcium with a 1 to 1 stoichiometry ### SEQUENCE -Y-E-G-H-C-Y-Q-T-F-K-L-F-K-T-W-A-D-A-E-S-F-C-T-E-Q-A-K-G-G-H-L-V-S-I-E-S-D-G-E-A-D-F-V-A-Q-L-V-A-E-N-I-Q-K-T-E-I-Y-V-W-V-G-L-R-V-Q-G-K-E-Q-Q-C-S-S-E-W-S-D-G-S-S-V-S-Y-Q-N-W-I-E-A-E-S-K-T-C-L-G-L-Q-K-E-T-E-F-R-K-W-F-N-I-Y-C-G-E-R-N-P-F-V-C-E-A


### FUNCTION Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly ### SEQUENCE -M-A-K-V-Q-I-L-N-M-V-V-L-D-N-P-C-P-F-H-N-P-F-Q-F-E-I-T-F-E-C-I-E-D-L-P-D-D-L-E-W-K-I-I-Y-V-G-S-A-E-S-E-E-Y-D-Q-T-L-D-S-V-L-V-G-P-V-P-A-G-R-H-M-F-V-F-Q-A-D-A-P-N-C-S-L-I-P-E-S-D-A-V-G-V-T-V-V-L-I-T-C-T-Y-R-G-Q-E-F-I-R-V-G-Y-Y-V-N-N-E-Y-S-D-P-E-L-R-E-N-P-P-L-K-A-H-F-G-Q-L-Q-R-N-I-L-A-S-N-P-R-V-T-R-F-H-I-N-W-E-C-T-S-E-A-K-M-E-D-I-E-N-V-D-P-A-S-N-T-M-L-P-P-N-C-A-P-S-K-G-L-A-A-A-L-N-T-L-P-E-N-S-M-D-C-M


### FUNCTION Regulates NF-kappa-B transcription factor activity Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation Promotes cardiac muscle hypertrophy Plays a role in the regulation of the growth of actin filaments Inhibits the activity of the F-actin-capping protein complex ### SEQUENCE -M-G-D-K-E-F-M-W-A-L-K-N-G-D-L-D-A-V-K-E-F-V-A-G-G-V-D-V-N-R-T-L-E-G-G-R-K-P-L-H-Y-A-A-D-C-G-Q-D-E-I-V-E-F-L-L-A-K-G-A-N-I-N-A-A-D-K-H-G-I-T-P-L-L-S-A-C-Y-E-G-H-R-K-C-V-E-L-F-V-S-K-G-A-D-K-N-V-K-G-P-D-G-L-N-A-F-E-S-T-D-N-Q-A-I-K-D-L-L-H


### FUNCTION Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids Adapter protein that may regulate the MAP kinase cascade ### SEQUENCE -M-A-E-E-L-K-R-F-L-Y-K-K-L-P-S-I-E-G-L-H-A-I-V-V-S-D-R-D-G-V-P-V-I-K-V-A-N-E-N-A-P-E-L-A-L-R-P-S-F-L-S-T-F-A-L-A-T-D-Q-G-S-K-L-G-L-S-K-N-K-S-I-I-C-Y-Y-D-T-C-Q-V-V-Q-F-N-R-L-P-L-V-V-S-F-I-A-S-S-D-A-N-T-G-L-L-L-S-L-N-E-E-L-G-D-L-F-E-E-L-Q-H-A-V-E-I


### FUNCTION Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor ### SEQUENCE -M-P-A-Y-H-S-I-L-M-E-S-D-T-K-L-I-G-N-M-A-M-L-P-I-R-S-Q-F-K-G-P-A-P-R-E-T-K-D-T-D-I-I-D-E-A-I-Y-Y-F-K-A-N-V-F-F-K-N-Y-E-I-K-N-E-A-D-R-T-L-I-Y-I-T-L-Y-I-S-E-C-L-K-K-L-Q-K-C-N-S-K-G-Q-G-E-K-E-M-Y-T-L-G-I-T-N-F-P-I-P-G-E-P-G-F-P-L-N-A-M-Y-V-K-P-S-N-K-Q-E-D-E-V-M-R-A-Y-L-Q-Q-L-R-Q-E-T-G-L-R-L-C-D-K-V-F-D-P-Q-T-D-K-P-S-K-W-W-I-C-F-V-K-K-Q-F-M-N-K-S-L-S-G-P-G-Q


### FUNCTION Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids Adapter protein that may regulate the MAP kinase cascade ### SEQUENCE -M-A-E-E-L-R-R-F-L-Y-K-K-L-T-S-V-E-G-L-H-A-I-V-V-S-D-R-D-G-V-P-V-I-K-V-A-N-E-N-A-P-E-Q-A-L-R-P-A-F-L-S-T-F-A-L-A-T-D-Q-G-S-K-L-G-L-S-K-N-K-S-I-I-C-Y-Y-S-T-Y-Q-V-V-Q-F-N-Q-L-P-L-V-V-S-F-I-A-S-S-N-A-N-T-G-L-I-L-S-L-E-K-E-L-G-S-L-F-K-E-L-R-Q-A-V-I-S


### FUNCTION Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum ### SEQUENCE -M-D-Q-V-M-Q-F-V-E-P-S-R-Q-F-V-K-D-S-I-R-L-V-K-R-C-T-K-P-D-R-K-E-F-Q-K-V-A-M-A-T-A-I-G-F-A-I-M-G-F-I-G-F-F-V-K-L-I-H-I-P-I-N-N-I-I-V-G-G


### FUNCTION Functions as a component of numerous distinct DCX  E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex ### SEQUENCE -M-D-K-A-D-F-L-K-G-L-P-V-Y-N-K-T-N-F-S-R-F-H-A-D-S-V-C-K-A-S-N-R-R-P-S-V-Y-L-P-T-R-E-Y-P-S-E-Q-I-I-V-T-E-K-T-N-I-L-L-R-Y-L-H-Q-Q-W-D-K-K-N-A-A-K-K-R-E-Q-E-Q-A-E-G-E-G-G-S-P-A-P-P-R-K-I-A-R-T-D-S-Q-E-M-N-E-D-S


### FUNCTION Regulates NF-kappa-B transcription factor activity Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation Promotes cardiac muscle hypertrophy Plays a role in the regulation of the growth of actin filaments Inhibits the activity of the F-actin-capping protein complex ### SEQUENCE -M-G-D-K-E-L-M-W-A-L-K-N-G-D-L-D-E-V-K-N-I-L-V-K-A-E-D-V-N-R-T-L-E-G-G-R-K-P-L-H-Y-A-A-D-C-G-Q-A-E-M-L-E-F-L-L-S-K-G-A-D-V-N-A-P-D-K-H-G-I-T-P-L-L-S-A-T-Y-E-G-H-V-T-C-V-K-I-L-L-E-K-G-A-D-K-N-R-K-G-P-D-G-L-S-A-F-E-A-A-E-S-E-A-I-K-A-L-L-E


### FUNCTION Binds to muscle nicotinic acetylcholine receptor  and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission ### SEQUENCE -K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-R-C-F-N-Q-Q-S-S-E-P-Q-T-N-K-S-C-P-P-G-E-N-S-C-Y-R-K-Q-W-R-D-H-R-G-T-I-I-E-R-G-C-G-C-P-T-V-K-P-G-V-K-L-R-C-C-E-S-E-D-C-N-N


### FUNCTION Binds with high affinity to muscular  and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission ### SEQUENCE -K-T-L-L-L-T-L-V-V-V-T-I-I-C-L-D-F-G-Y-T-R-I-C-F-K-T-P-Y-V-K-S-E-T-C-P-P-G-Q-E-L-C-Y-T-K-T-W-C-D-R-F-C-S-I-R-G-K-V-I-E-L-G-C-T-A-T-C-P-R-A-E-P-K-E-D-T-T-C-C-S-K-D-N-C-N-P-H-P


### FUNCTION May play a role in bone development ### SEQUENCE -M-S-E-T-N-Q-Q-R-D-D-L-P-A-Y-L-N-D-E-P-P-A-D-A-N-K-D-H-P-Q-P-Q-P-G-M-F-S-R-V-A-G-G-L-F-S-V-T-K-G-A-V-G-A-T-V-G-G-V-A-W-V-G-G-K-S-F-D-L-T-K-T-A-V-T-S-V-A-S-V-P-A-M-G-V-G-L-V-K-G-G-V-S-A-V-A-G-G-V-T-A-V-G-S-A-V-V-S-K-V-P-I-G-G-G-K-K-K-D-K-S-D


### FUNCTION Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis Negative regulator of Toll-like receptor and T-cell receptor function Prevents hyperresponsiveness of the immune system and maintains immune homeostasis Inhibits jun/ap1 and NF-kappa-B activation Promotes Fas-induced apoptosis ### SEQUENCE -M-E-T-F-S-S-K-D-M-A-L-K-A-Q-K-K-I-L-S-K-M-A-T-K-S-M-V-Q-M-I-I-D-D-T-S-S-E-I-L-D-E-L-Y-R-V-S-K-E-Y-T-G-N-R-S-E-A-Q-K-V-V-K-D-L-I-K-V-V-V-K-I-G-V-L-F-R-H-N-R-F-N-E-E-E-L-K-L-A-Q-N-F-Q-K-K-L-R-Q-G-A-M-T-A-I-S-F-H-E-V-D-F-T-F-D-K-T-V-M-S-D-I-L-T-E-S-R-D-M-L-L-K-L-V-N-T-H-L-T-T-K-S-H-G-R-I-N-H-V-F-N-H-Y-A-D-P-E-L-L-T-Q-L-Y-N-S-S-G-P-L-K-P-H-L-N-K-I-C-N-G-L-N-K-L-L-E-N-G-T-L


### FUNCTION Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding Calcium-binding is required for the activation of calmodulin Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II , and phosphatases ### SEQUENCE -M-A-D-Q-L-T-E-E-Q-I-A-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-T-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-Q-D-M-I-N-E-V-D-A-D-G-N-G-T-I-D-F-P-E-F-L-T-M-M-A-R-K-M-K-D-T-D-S-E-E-E-I-R-E-A-F-R-V-F-D-K-D-G-N-G-Y-I-S-A-A-E-L-R-H-V-M-T-N-L-G-E-K-L-T-D-E-E-V-D-E-M-I-R-E-A-D-I-D-G-D-G-Q-V-N-Y-E-E-F-V-Q-I-M-T-A-K


### FUNCTION May function in the formation of membrane-bound replication complexes or in the assembly of the virus ### SEQUENCE -M-L-V-F-L-H-A-V-F-V-T-V-L-I-L-L-L-I-G-R-L-Q-L-L-E-R-L-L-L-N-H-S-L-N-L-K-T-V-N-N-V-L-G-V-T-D-T-G-L-K-V-N-C-L-Q-L-L-K-P-D-C-L-D-F-N-I-L-Y-R-S-L-A-E-T-R-L-L-K-V-V-L-R-V-I-F-L-V-L-L-G-F-C-C-H-R-L-L-V-T-L-F


### FUNCTION Plays a central role in virus morphogenesis and assembly Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport Also plays a role in the induction of apoptosis ### SEQUENCE -M-T-F-P-R-A-L-T-V-I-D-D-N-G-M-V-I-S-I-I-F-W-L-L-L-I-I-I-L-I-L-F-S-I-A-L-L-N-I-I-K-L-C-M-V-C-C-N-L-G-R-T-V-V-V-I-P-V-R-H-A-Y-D-A-Y-K-N-F-M-R-I-N-A-Y-N-H-N-E-A-L-L-V


### FUNCTION Cell-to-cell movement function ### SEQUENCE -M-K-V-L-L-V-T-G-V-L-G-L-L-L-L-I-K-W-K-S-Q-S-T-S-T-S-N-Q-T-C-Q-C-P-T-S-P-W-V-I-Y-A-F-Y-N-S-L-S-L-V-L-L-L-C-H-L-I-P-E-I-K-P-I-H-T-S-Y-N-T-H-D-S-S-K-Q-Q-H-I-S-I-N-T-G-N-G-K


### FUNCTION May be involved in cell cycle regulation ### SEQUENCE -M-G-A-S-C-T-A-T-Q-S-Q-F-L-L-Y-T-L-T-S-S-E-E-T-V-G-S-V-G-D-S-C-R-G-P-E-E-E-A-E-K-P-V-K-T-K-T-V-S-S-S-N-G-G-E-S-S-S-R-S-A-E-K-R-S-A-E-D-E-A-A-D-L-P-T-K-P-T-K-M-S-K-F-G-F-A-I-G-S-Q-T-A-R-K-A-S-A-I-S-I-R-L-G-A-S-K-P-K-E-T-V-P-T-L-A-P-K-T-L-S-V-A-A-A-F-N-E-D-E-D-S-E-P-E-E-M-P-P-E-A-K-M-R-M-K-N-I-G-R-D-T-P-T-S-A-G-P-N-S-F-N-K-G-K-H-G-F-S-D-N-Q-K-L-W-E-R-N-I-K-S-H-L-G-N-V-H-D-Q-D-N


### FUNCTION Does not bind lactose, and may not bind carbohydrates ### SEQUENCE -M-A-G-L-G-A-N-S-D-V-M-V-K-L-D-D-G-H-L-N-N-S-L-R-S-P-V-Q-A-G-V-Y-F-R-G-H-I-K-G-G-M-R-P-G-K-K-V-L-V-M-G-I-V-D-H-N-P-K-S-F-A-I-S-L-T-C-G-D-S-E-D-P-P-A-D-V-A-I-E-L-K-V-V-F-T-N-Q-Q-V-F-R-N-S-C-I-S-G-E-S-D-E-E-N-L-A-F-P-Y-F-P-F-V-P-D-Q-P-F-R-M-E-I-F-C-Q-Q-P-C-F-R-V-L-V-D-G-H-H-L-F-D-F-Y-H-R-I-Q-T-L-S-A-I-D-S-I-K-I-S-G-D-L-Q-I-T-K-L-G


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-F-E-F-P-A-S-F-R-F-A-D-S-H-E-Y-A-N-A-D-G-E-L-V-R-V-G-I-S-A-F-A-V-D-Q-L-G-D-I-V-F-V-D-L-P-D-V-G-D-S-L-D-K-G-A-T-F-G-S-V-E-S-V-K-A-V-E-D-M-Y-A-P-V-A-G-E-V-V-Q-R-N-E-A-V-L-A-S-P-E-E-L-Q-N-D-P-H-G-E-G-W-L-L-V-L-R-P-S-D-P-S-Q-L-E-A-L-M-D-A-G-T-Y-G-T-K-V-N-A-G


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-Q-G-R-R-V-E-R-V-A-A-L-I-R-K-E-T-S-E-L-L-I-N-G-I-R-D-E-R-V-H-Q-G-M-V-S-I-T-N-V-E-V-S-G-D-L-Q-H-C-K-I-F-V-S-I-F-G-D-E-A-S-Q-L-Q-V-M-E-G-L-Q-A-A-S-G-Y-L-K-G-E-L-G-R-R-L-Q-M-R-R-A-P-D-V-V-F-Q-L-D-R-G-I-E-R-G-T-S-V-L-G-L-L-N-K-L-E-D-E-R-K-E-R-G-E-I-P-A-G-S-D-E-L-P-A-E


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-Q-T-Y-I-R-S-I-P-D-F-P-K-P-G-I-L-F-R-D-I-N-P-L-L-R-N-P-A-A-M-V-E-V-M-R-R-L-G-A-I-C-D-A-V-Q-P-D-L-I-V-G-I-E-S-R-G-F-I-V-G-T-P-L-A-L-Q-R-S-L-G-F-V-P-V-R-K-P-G-K-L-P-G-A-V-I-G-V-D-Y-A-L-E-Y-G-T-D-R-L-E-I-Q-S-D-A-L-T-G-N-P-R-V-L-V-V-D-D-L-L-A-T-G-G-T-A-A-A-T-G-S-L-V-R-A-A-G-G-E-L-V-G-F-A-F-V-I-E-L-E-P-L-G-G-R-S-A-L-P-D-E-V-L-A-E-S-L-I-R-Y-P


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-A-V-S-L-S-V-S-T-V-K-P-L-G-D-R-V-F-I-K-V-S-E-S-E-E-K-T-A-G-G-I-L-L-P-D-T-A-K-E-K-P-Q-V-G-E-V-V-Q-V-G-P-G-K-R-N-D-D-G-S-R-Q-A-P-E-V-G-V-G-D-K-V-L-Y-S-K-Y-A-G-T-D-I-K-L-G-G-D-E-F-V-L-L-T-E-K-D-I-L-A-I-V-N


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-Y-K-F-P-N-Y-L-R-Y-A-D-T-H-E-Y-V-K-E-E-N-G-L-F-K-I-G-V-S-E-F-A-I-D-Q-L-G-D-I-V-F-V-E-L-V-E-K-G-T-N-L-Q-K-G-E-T-F-G-T-I-E-S-V-K-A-V-E-E-V-Y-L-P-F-S-G-E-V-I-S-V-N-E-G-V-I-D-N-P-E-I-L-Q-N-D-P-I-G-D-G-W-L-L-I-I-K-S-E-S-N-V-L-L-D-E-L-M-N-S-D-E-Y-K-S-K-V-V-P-N


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-P-P-R-P-R-F-D-R-R-A-P-V-R-E-L-P-N-I-N-E-R-I-K-Y-P-Q-L-R-V-V-D-S-D-G-K-Q-L-G-V-I-D-R-I-K-A-L-E-I-A-H-Q-R-G-L-D-L-V-L-V-S-E-K-A-N-P-P-V-C-R-I-M-D-Y-G-K-Y-K-F-E-Q-E-K-K-A-K-E-T-K-K-K-S-H-Q-T-E-V-K-E-V-K-M-R-Y-K-I-D-K-H-D-Y-D-V-R-I-G-Q-A-V-R-F-L-K-S-G-D-K-V-K-C-T-V-F-F-R-G-R-E-I-Q-H-S-N-L-A-E-T-L-L-L-K-M-A-N-D-L-E-E-Q-S-E-V-Q-Q-R-P-K-R-E-G-R-N-M-I-M-F-L-S-P-R-K-T-P-L-I-K-K-E-E-G


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-I-A-D-S-L-L-K-K-V-E-K-Q-N-T-D-N-D-K-S-V-I-K-T-W-S-R-S-S-T-I-L-P-V-M-I-G-H-T-I-A-V-H-N-G-K-A-H-I-P-V-F-I-T-E-Q-M-I-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-L-R-D-K-K-G-A-R


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-L-K-E-R-I-G-T-V-V-S-D-K-M-D-K-T-V-V-V-A-V-I-N-R-Y-P-H-P-T-Y-K-K-I-V-S-K-T-T-R-Y-K-A-H-D-P-E-N-S-C-V-L-G-D-R-V-K-I-K-E-T-R-P-L-S-A-H-K-R-W-A-I-E-E-I-L-N-K-T-I-M-S-K-E-D-K-K


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-Y-L-T-V-A-D-N-S-G-A-K-R-L-Q-C-I-R-V-L-G-S-N-R-R-Y-A-H-V-G-D-V-V-V-A-S-V-K-D-A-L-P-N-M-G-V-K-K-S-D-V-V-K-A-V-I-V-R-T-R-H-T-L-R-R-N-T-G-N-S-I-R-F-D-D-N-A-A-V-L-I-N-E-D-K-N-P-K-G-T-R-V-F-G-P-V-A-R-E-L-R-D-K-N-F-T-K-I-V-S-L-A-P-E-V-I


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-N-K-S-A-K-K-R-I-Q-V-A-E-R-N-R-L-V-N-K-S-Y-K-S-T-V-R-T-L-T-K-K-T-L-A-N-C-E-K-Y-K-Q-E-P-N-S-D-N-K-D-L-V-L-V-S-V-N-Q-A-F-S-L-I-D-K-A-V-K-K-N-V-L-H-K-N-N-G-A-N-K-K-S-K-I-N-K-V-V-K-D-F-L-T-S-K


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-I-S-L-K-V-L-A-P-N-Q-N-V-Y-E-G-D-A-E-E-V-I-L-P-S-T-T-G-Q-I-G-V-L-P-G-H-I-S-L-V-T-A-I-D-I-G-V-L-R-L-R-M-N-S-K-W-K-S-I-A-L-M-G-G-F-A-E-I-E-S-D-E-V-I-V-L-V-N-S-A-E-I-G-S-E-I-N-I-Q-N-A-E-D-A-L-K-K-A-K-S-A-I-S-K-F-P-E-N-E-K-S-S-E-K-I-K-A-L-N-E-V-S-K-A-E-A-R-I-Q-A-S-K-N


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-A-V-S-L-T-V-S-T-V-K-P-L-G-D-R-I-F-I-K-V-S-E-S-E-E-K-T-A-G-G-I-L-L-P-D-S-A-K-E-K-P-Q-V-G-E-V-A-Q-V-G-P-G-K-L-N-D-D-G-S-R-Q-T-P-E-V-S-I-G-D-K-V-L-Y-S-K-Y-A-G-T-D-I-K-L-G-G-D-E-Y-V-L-L-S-E-K-D-I-L-A-V-V-G


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-R-E-V-K-R-K-K-L-V-K-K-Y-A-T-K-R-K-S-L-L-D-E-F-N-A-A-K-D-P-M-E-R-L-E-I-H-R-K-I-Q-G-L-P-R-N-S-A-P-T-R-V-R-N-R-C-W-A-T-G-K-P-R-G-V-Y-R-D-F-G-L-C-R-N-Q-L-R-L-R-A-H-N-G-E-L-P-G-V-V-K-S-S-W


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-T-L-D-T-A-E-K-Q-K-L-I-E-S-H-Q-V-H-A-T-D-T-G-S-V-E-V-Q-V-A-M-L-S-E-R-I-S-K-L-S-D-H-L-Q-G-N-I-H-D-Y-A-S-R-Q-G-L-L-K-M-I-G-K-R-K-R-L-L-S-Y-I-K-G-K-N-P-Q-N-Y-Q-D-L-I-K-K-I-G-I-R-G


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-P-N-S-I-F-K-K-Q-L-S-P-I-K-P-G-D-P-I-D-Y-K-D-V-E-L-L-K-K-F-I-T-E-R-G-K-I-L-P-R-R-M-T-G-L-T-S-K-Q-Q-R-D-L-T-L-A-V-K-R-A-R-I-V-A-L-L-P-F-V-N-P-E-G


### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-S-T-L-K-K-P-D-L-S-D-P-K-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-V-V-I-L-G-T-I-A-C-V-V-G-L-A-V-L-D-P-A-M-L-G-D-K-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-L-Y-P-V-F-Q-I-L-R-V-V-P-N-K-L-L-G-I-A-L-Q-T-L-I-P-L-G-L-M-I-L-P-F-I-E-N-V-N-K-F-S-N-P-F-R-R-P-V-A-M-S-V-F-L-F-G-T-F-L-T-I-Y-L-G-I-G-A-C-L-P-I-D-K-S-L-T-L-G-L-F


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-T-T-N-F-G-F-V-A-S-L-L-F-V-G-I-P-T-I-F-L-I-G-L-F-I-S-T-Q-D-G-E-K-S-S-F-Y-S-D-S-S-K-G-K-L-G-P-K-R


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-F-Q-F-P-D-H-F-R-F-A-D-T-H-E-Y-A-S-L-D-G-E-L-V-R-I-G-I-S-A-F-A-V-D-Q-L-G-D-I-V-F-V-D-L-P-E-V-G-D-R-L-N-R-G-T-T-F-G-S-V-E-S-V-K-A-V-E-D-L-H-A-P-I-S-G-E-L-V-R-I-N-E-S-V-L-S-S-P-D-E-L-Q-N-D-P-H-G-E-G-W-L-L-V-V-R-P-A-D-P-A-Q-L-Q-D-L-M-D-A-A-T-Y-A-N-K-V-A-I-E-S-S-N


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-K-I-T-A-K-D-V-R-K-V-A-Q-L-A-R-L-D-L-P-D-D-Q-I-A-T-Y-T-E-Q-L-E-R-I-L-A-Y-V-A-Q-L-E-E-I-D-T-T-N-V-K-P-T-T-R-A-V-E-V-V-N-V-T-R-T-D-E-V-S-E-T-P-V-R-E-E-L-L-N-L-A-P-Q-R-E-G-D-F-F-R-V-P-K-I-L-A-E


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-F-L-T-V-A-D-N-S-G-A-K-R-I-Q-C-I-R-V-L-G-S-N-R-R-Y-A-H-V-G-D-V-I-V-A-A-V-K-D-A-M-P-N-M-S-V-K-K-S-E-V-V-K-A-V-V-V-R-T-K-A-T-L-R-R-D-T-G-N-S-I-R-F-D-D-N-A-A-V-L-I-N-E-D-K-N-P-R-G-T-R-V-F-G-P-V-A-R-E-L-R-E-R-N-F-T-K-I-V-S-L-A-P-E-V-I


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-L-K-E-R-L-G-T-V-V-S-D-K-M-D-K-T-V-V-V-A-V-E-N-R-F-P-H-P-I-Y-Q-K-T-V-S-R-T-T-R-Y-K-A-H-D-A-G-N-T-C-R-V-G-D-R-V-R-I-T-E-T-R-P-L-S-R-S-K-R-W-T-V-A-E-V-L-S-H-S-P-K-A-Q-E-V-S-T


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-I-A-D-S-L-L-R-K-L-E-K-Q-N-A-D-D-D-K-S-V-I-K-T-W-S-R-A-S-T-I-L-P-M-M-I-G-H-T-I-A-V-H-N-G-R-S-H-V-P-V-F-I-T-E-Q-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-K-G-H-I-K-D-K-K-G-G-R


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-P-V-N-N-F-G-F-L-A-T-L-L-F-V-A-V-P-M-L-F-L-I-G-L-Y-I-Q-T-N-S-N-K-S


### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-H-I-L-K-K-P-D-F-S-D-P-K-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-V-V-I-L-G-T-F-A-C-L-V-G-L-A-V-L-D-P-A-M-L-G-D-K-A-D-P-F-A-T-P-L-E-I-L-P-E-W-Y-L-Y-P-V-F-Q-I-L-R-V-V-P-N-K-L-L-G-I-A-L-Q-T-L-V-P-L-G-L-M-L-I-P-F-I-E-S-V-N-K-Y-Q-N-P-F-R-R-P-I-A-M-A-F-F-L-F-G-T-V-I-T-I-Y-L-G-I-G-A-C-L-P-I-D-K-S-L-T-L-G-L-F


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-N-K-S-S-K-K-R-V-Q-I-A-E-R-N-R-L-E-N-K-S-Y-K-S-A-M-R-T-L-M-K-R-C-F-S-A-C-S-H-Y-S-Q-Q-P-G-E-T-A-K-A-N-V-K-A-S-I-D-S-A-F-S-K-I-D-K-A-V-K-R-G-V-L-H-R-N-T-A-A-H-Q-K-S-R-L-S-A-A-V-K-Q-A-I-E-P-A-P-S-T


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-A-V-S-L-S-V-S-T-V-K-P-L-G-D-R-V-F-V-K-V-S-E-S-E-E-K-T-A-G-G-I-L-L-P-D-T-A-K-E-K-P-Q-V-G-E-V-V-Q-V-G-P-G-K-R-N-D-D-G-S-R-Q-A-P-E-V-G-V-G-D-K-V-L-Y-S-K-Y-A-G-T-D-I-K-L-S-T-D-E-Y-V-L-L-S-E-K-D-I-L-A-V-V-N


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-R-D-V-K-R-K-K-I-V-E-R-Y-A-A-K-R-A-A-L-M-E-A-F-N-A-A-K-D-P-M-Q-R-L-E-I-H-R-K-I-Q-A-L-P-R-N-S-A-P-N-R-I-R-N-R-C-W-A-T-G-K-P-R-G-V-Y-R-D-F-G-L-C-R-N-Q-L-R-E-R-A-H-K-G-E-L-P-G-V-V-K-S-S-W