### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-T-E-N-T-H-A-G-R-L-I-V-L-T-G-P-T-A-V-G-K-G-T-V-E-A-K-L-R-A-D-H-P-E-V-W-V-S-V-S-A-T-T-R-A-P-R-P-G-E-V-D-G-V-N-Y-W-F-L-T-E-D-E-F-L-A-R-E-A-A-G-E-F-L-E-T-A-V-V-H-G-M-A-H-Y-G-T-L-L-K-P-V-E-E-H-L-A-A-G-V-P-T-I-L-E-I-D-L-Q-G-A-R-R-V-K-Q-R-A-A-E-L-D-L-E-V-V-Y-V-F-I-A-P-P-S-F-E-E-L-E-R-R-L-I-G-R-G-T-E-T-A-E-Q-Q-A-R-R-L-E-T-A-K-V-E-L-A-A-E-S-E-F-D-V-T-I-V-N-E-T-V-D-Q-A-A-A-D-L-W-S-V-I-A-K-E-Y-G-L


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-A-R-S-T-A-R-K-R-A-L-N-T-L-Y-E-A-D-E-K-S-Q-D-I-L-S-L-L-D-E-R-I-A-H-P-G-A-Q-T-P-L-P-D-Y-A-I-E-I-V-K-G-V-A-E-H-R-R-Q-I-D-M-T-L-D-E-H-S-T-G-W-K-V-R-R-M-G-V-V-D-R-N-I-L-R-I-A-A-W-E-I-L-F-T-D-D-V-P-D-K-V-A-I-D-E-A-L-A-L-A-K-T-L-C-D-D-D-S-P-A-F-I-H-G-L-L-S-A-V-C-T-A-K-N-A-A-P-A-P-E-S-V-A-E-E-A-D-E-E-S-S-D-S-A-A-A-A-S-E-P-T-D-E-G-D-V-S-D-S-P-D-S-S-G-A-S-D-E-P-A-A-P-S-A-E-I-Q-P-T-V-D


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-Q-T-T-N-D-I-K-N-G-S-V-L-N-L-D-G-Q-L-W-T-V-M-K-F-Q-H-V-K-P-G-K-G-P-A-F-V-R-T-T-I-K-N-V-L-S-G-K-I-V-D-K-T-F-N-A-G-M-K-M-E-F-E-T-V-D-N-R-T-L-Q-Y-S-Y-E-D-G-D-N-F-V-F-M-D-M-T-T-Y-D-Q-I-M-V-P-K-T-L-L-G-D-K-A-K-F-L-L-E-G-T-D-C-L-V-S-F-H-D-G-T-P-L-S-V-D-L-P-G-S-V-V-L-T-I-T-H-T-E-P-G-L-Q-G-N-R-S-N-A-G-T-K-P-A-T-V-E-T-G-A-E-I-Q-V-P-L-F-I-N-E-G-D-R-V-K-I-N-T-E-D-G-S-Y-T-G-R-E-N-N


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-G-V-S-V-K-P-A-A-R-R-N-A-R-Q-F-A-L-Q-A-I-Y-S-W-Q-L-S-K-E-N-V-A-D-I-E-E-Q-F-L-T-A-E-K-Y-D-E-E-E-H-H-A-N-E-P-K-L-Q-T-P-E-T-D-V-A-Y-F-R-D-L-F-S-G-V-A-L-N-H-M-K-L-D-G-K-M-R-P-Y-L-S-R-P-L-Q-D-L-D-Q-M-E-L-A-L-L-R-M-S-I-Y-E-M-M-N-R-D-D-V-P-Y-K-V-V-I-N-E-A-I-E-L-A-K-V-F-A-A-E-D-S-H-K-F-V-N-G-V-L-D-K-A-A-P-T-L-R-K-K


### FUNCTION Overproduction of CaiE stimulates the activity of CaiB and CaiD ### SEQUENCE -M-S-I-Y-A-F-E-G-V-I-P-V-V-H-P-T-A-Y-I-H-P-S-A-V-L-I-G-D-V-I-I-G-A-G-V-Y-I-G-P-L-A-S-L-R-G-D-Y-G-R-L-I-V-E-A-G-A-N-L-Q-D-G-C-V-M-H-G-Y-T-D-M-D-T-I-V-Q-E-N-G-H-I-G-H-G-A-I-L-H-S-C-I-I-G-R-D-S-L-V-G-M-N-S-V-I-M-D-G-A-I-I-G-E-E-S-I-V-A-A-M-S-F-V-K-A-G-F-Q-G-Q-A-R-Q-M-L-M-G-S-P-A-K-H-V-R-D-I-S-D-Q-D-M-Q-W-K-R-M-N-T-R-E-Y-Q-D-L-T-V-R-C-R-Q-G-L-V-E-T-T-P-L-T-A-P-E-A-N-R-P-R-L-R-G-T-T-E-V-K-P-K-G-Q


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-V-E-E-K-E-Q-T-V-G-G-F-V-L-A-G-S-A-Q-E-K-T-K-T-A-Q-V-V-A-T-G-Q-G-V-R-T-L-N-G-D-L-V-A-P-S-V-K-A-G-D-R-V-L-V-E-A-H-A-G-L-D-V-K-D-G-D-E-K-Y-I-I-V-G-E-A-N-I-L-A-I-I-E-K


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-T-K-F-R-P-L-H-D-R-V-V-V-R-R-L-E-G-E-Q-K-T-A-G-G-I-I-I-P-D-T-A-Q-E-K-P-M-E-G-E-V-V-A-V-G-P-G-A-R-N-E-Q-G-Q-I-V-A-L-D-V-K-A-G-D-R-V-L-F-G-K-W-S-G-T-E-V-K-I-D-G-E-E-L-L-I-M-K-E-S-D-I-M-G-V-V-T-A


### FUNCTION Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization ### SEQUENCE -M-L-L-Q-G-T-H-R-I-G-R-M-A-M-L-L-A-L-A-D-E-N-E-S-P-V-L-S-I-P-K-G-W-K-Y-C-T-G-K-V-G-S-M-N-S-Q-K-V-V-A-A-M-E-T-A-A-K-S-N-Q-V-I-E-T-D-V-Y-R-E-T-H-A-L-Y-H-A-I-M-E-A-L-Y-G-V-T-R-G-Q-I-Q-L-A-D-V-L-R-T-V-G-L-R-F-A-I-V-R-G-T-P-Y-D-G-K-K-E-G-E-W-V-A-V-A-L-Y-G-T-I-G-A-P-V-K


### FUNCTION Involved in chromosome condensation, segregation and cell cycle progression May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division Not required for mini-F plasmid partitioning Probably acts via its interaction with MukB and MukE Overexpression results in anucleate cells It has a calcium binding activity ### SEQUENCE -M-S-D-F-S-Q-T-V-P-E-L-V-A-W-A-R-K-N-D-F-A-L-T-L-P-T-E-R-L-A-F-L-L-A-I-A-T-L-N-G-E-R-L-D-G-E-M-S-E-G-D-L-V-D-V-F-R-H-V-S-K-T-F-E-Q-T-H-E-T-V-A-Q-R-A-N-N-A-I-N-D-L-V-K-Q-R-L-L-N-R-F-T-S-E-L-A-E-G-N-A-I-Y-R-L-T-P-L-G-I-S-I-S-D-Y-Y-I-R-Q-R-E-F-S-T-L-R-L-S-M-Q-L-S-I-V-A-Q-E-L-R-A-A-G-D-A-A-E-E-G-G-D-E-F-H-W-H-R-N-V-F-A-P-L-K-Y-S-V-A-E-I-F-D-S-I-D-L-T-Q-R-L-M-D-E-A-A


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-D-S-S-N-A-H-E-A-E-N-P-T-V-P-T-P-D-N-E-I-Q-D-L-Q-Q-E-I-A-T-L-K-A-E-L-K-E-K-N-D-K-Y-L-M-V-L-A-E-S-E-N-A-R-K-R-M-Q-K-E-R-Q-E-M-M-Q-Y-A-V-E-N-A-L-I-D-F-L-V-P-I-E-S-M-E-K-A-L-G-F-A-S-Q-M-S-D-E-V-K-N-W-A-L-G-F-N-M-I-L-Q-Q-F-K-Q-V-F-E-E-K-G-I-V-E-Y-S-S-V-G-Q-K-F-N-P-F-L-H-E-A-V-E-T-E-E-T-T-K-V-P-E-G-T-I-V-E-E-F-S-K-G-Y-K-I-G-D-R-P-I-R-V-A-K-V-K-V-S-K-A-P-A-P-Q-G-T-E-A-E-I-E-N-N-N-E


### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-L-A-E-S-V-L-G-N-L-K-E-G-G-S-S-K-E-L-D-F-I-D-L-E-W-F-D-A-Q-K-R-M-G-R-F-T-S-Q-K-G-A-E-L-V-L-K-L-K-N-P-P-K-M-G-L-C-D-G-D-I-L-F-E-D-A-T-S-L-I-A-I-N-I-I-P-T-P-T-L-H-V-Y-A-D-S-T-A-Q-V-A-R-L-C-Y-E-V-G-N-R-H-A-S-L-Y-Y-G-D-S-P-L-S-F-K-T-P-F-E-R-P-L-Q-V-L-F-D-K-L-A-L-R-Y-E-V-L-K-S-K-L-D-A-S-Q-R-I-S-V-S-A-P-H-A-D-P-L-Q-E-G-S-A-P-L-K-F-K-S-A-L-D-L-Q-I-V-I-K-K


### FUNCTION Specifically methylates the N7 position of guanine in position 527 of 16S rRNA ### SEQUENCE -M-R-A-K-L-D-L-F-T-H-L-L-L-E-W-G-S-V-H-N-L-S-G-A-K-N-H-Q-D-I-E-H-N-I-Q-D-S-L-Q-V-L-D-F-I-A-P-F-K-S-C-L-D-I-G-S-G-A-G-F-P-A-I-P-L-S-L-A-C-S-N-A-R-F-I-L-L-E-P-N-A-K-K-V-A-F-L-H-H-V-K-L-A-L-N-L-N-N-L-E-I-Q-R-M-R-I-E-H-V-S-P-Q-S-V-L-V-D-L-I-T-S-R-A-L-M-N-A-Q-N-L-I-A-L-S-A-P-F-L-R-E-Q-G-H-F-L-F-Y-K-G-S-H-L-R-T-E-I-A-C-A-D-H-E-C-H-V-Y-G-K-R-V-Y-F-Y-S-Q-R-R-D-F-A


### FUNCTION May function as a transcriptional regulator that controls feoABC expression ### SEQUENCE -M-A-G-L-L-Q-V-R-D-A-L-A-L-R-A-T-S-G-A-Q-L-S-Q-S-L-A-T-P-L-P-L-V-Q-A-M-L-D-R-L-T-A-M-G-K-V-E-R-I-E-Q-D-D-G-A-C-L-S-G-G-C-K-S-C-P-Q-P-R-G-A-A-R-C-S-T-G


### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-N-P-Q-P-S-G-M-T-W-N-L-L-L-L-T-W-L-V-A-L-I-S-T-L-S-A-L-F-I-G-E-V-M-G-Q-A-P-C-V-L-C-W-F-Q-R-A-F-M-F-P-L-T-V-I-L-A-I-A-C-Y-R-S-D-F-T-V-W-R-Y-A-L-P-L-T-V-I-G-A-A-L-A-F-V-H-T-L-L-Y-A-G-L-I-P-Q-P-I-Q-P-C-T-A-T-G-P-S-C-S-G-A-G-M-T-L-F-G-V-V-P-L-P-A-L-A-L-F-A-F-I-I-I-A-I-L-L-I-I-I-R-R-R-T-T-P


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-K-P-I-G-E-R-V-L-L-K-P-I-K-K-E-E-K-T-K-S-G-I-L-L-S-S-K-S-S-N-T-D-T-K-N-E-A-E-V-V-A-L-G-K-G-E-K-L-E-G-I-K-V-G-D-K-V-I-F-N-K-F-S-G-N-E-I-E-D-G-D-I-K-Y-L-I-V-N-A-D-D-I-L-A-V-I-E


### FUNCTION May act as a membrane anchor for the tetrachloroethene reductive dehalogenase PceA ### SEQUENCE -M-N-I-Y-D-V-L-I-W-M-A-L-G-M-T-A-L-L-I-Q-Y-G-I-W-R-Y-L-K-G-K-G-K-D-T-I-P-L-Q-I-C-G-F-L-A-N-F-F-F-I-F-A-L-A-W-G-Y-S-S-F-S-E-R-E-Y-Q-A-I-G-M-G-F-I-F-F-G-G-T-A-L-I-P-A-I-I-T-Y-R-L-A-N-H-P-A-K-K-I-R-E-S-S-D-T-I-S-A


### FUNCTION May act as a membrane anchor for the tetrachloroethene reductive dehalogenase PceA ### SEQUENCE -M-N-I-Y-D-V-L-I-W-M-A-L-G-M-T-A-L-L-I-Q-Y-G-I-W-R-Y-L-K-G-K-G-K-D-T-I-P-L-Q-I-C-G-F-L-A-N-F-F-F-I-F-A-L-A-W-G-Y-S-S-F-S-E-R-E-Y-Q-A-I-G-M-G-F-I-F-F-G-G-T-A-L-I-P-A-I-I-T-Y-R-L-A-N-H-P-A-K-K-I-R-E-S-S-D-S-I-S-A


### FUNCTION Catalyzes the reduction of arsenate ### SEQUENCE -M-S-K-K-T-L-Y-F-L-C-T-G-N-S-C-R-S-Q-M-A-E-G-W-A-K-K-Y-L-N-N-N-E-W-D-V-R-S-A-G-L-E-A-H-G-L-N-P-N-A-V-K-A-M-K-E-A-G-V-D-I-S-N-Q-T-S-D-V-I-D-P-E-I-L-N-N-A-D-L-V-V-T-L-C-G-H-A-A-D-H-C-P-V-T-P-P-H-V-K-R-E-H-W-G-F-D-D-P-A-K-A-E-G-T-D-E-E-K-W-A-F-F-Q-R-V-R-D-E-I-A-E-R-I-Q-R-F-A-E-T-G-K


### FUNCTION Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine ### SEQUENCE -I-A-G-C-Q-N-V-V-L-C-S-P-P-P-I-A-D-E-I-L-Y-A-A-Q-L-C-G-V-Q-E-I-F-N-V-G-G-A-Q-A-I-A-A-L-A-F-G-S-E-S-V-P-K-V-D-K-I-F-G-P-G-N-A-F-V-T-E-A-K-R-Q-V-S-Q-R-L-D-G-A-A-I-D-M-P-A-G-P-S-E-V-L-V-I-A-D-S-G-A-T-P-D-F-V-A-S-D-L-L-S-Q-A-E-H-G-P-D-S-Q-V-I-L-L-T-P-D-A-D-I-A-R-K-V-A-E-A-V-E-R-Q-L-A-E-L-P-R-A-D-T-A-R-Q-A-L-S-A-S-R-L-I-V-T-K-D-L-A-Q-C-V


### FUNCTION Represses transcription of the icaADBC operon necessary for biofilm production ### SEQUENCE -M-K-D-K-I-I-D-N-A-I-T-L-F-S-E-K-G-Y-D-G-T-T-L-D-D-I-S-K-S-V-N-I-K-K-A-S-L-Y-Y-H-Y-D-N-K-E-E-I-Y-R-K-S-V-E-N-C-F-N-Y-F-I-D-F-L-L-R-N-H-D-D-N-Y-S-I-D-G-L-Y-Q-F-L-F-K-F-I-F-D-V-D-E-R-Y-I-K-L-Y-V-Q-L-S-S-A-P-E-A-L-N-S-E-I-K-H-H-L-Q-E-I-N-T-T-L-H-D-E-L-I-K-Y-Y-D-P-T-H-I-A-L-N-K-E-D-F-I-N-L-I-L-L-F-L-E-T-W-Y-F-R-A-S-F-S-Q-K-F-G-V-I-E-D-S-K-N-R-F-K-D-Q-V-Y-S-L-L-N-V-F-L-K-K


### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-D-Y-F-T-L-F-G-L-P-A-R-Y-A-L-D-R-E-L-L-A-T-R-Y-Q-E-L-Q-R-Q-F-H-P-D-R-F-A-N-Q-P-E-R-E-K-T-L-A-L-Q-Q-A-T-T-I-N-T-G-Y-Q-T-L-K-H-P-L-K-R-A-E-Y-M-L-S-Q-Q-G-F-D-L-S-N-E-Q-H-T-M-Q-D-T-A-F-L-M-Q-Q-L-E-L-R-E-E-L-D-A-I-E-H-S-S-D-T-E-A-V-L-S-G-F-S-S-R-L-N-K-M-I-K-T-R-R-E-Q-M-E-Q-Q-L-D-A-A-E-W-L-I-A-A-D-T-V-R-K-L-R-F-L-D-K-L-Q-Q-Q-V-E-Q-L-E-E-R-L-L-G-D-F


### FUNCTION Is able to transfer iron-sulfur clusters to apo-ferredoxin Multiple cycles of  cluster formation and transfer are observed, suggesting that IscA acts catalytically Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB ### SEQUENCE -M-S-I-S-L-T-E-S-A-A-Q-R-I-V-A-F-L-D-N-R-G-K-G-V-G-L-R-L-G-V-R-T-S-G-C-S-G-M-A-Y-V-L-E-F-A-D-V-V-N-E-E-D-Q-V-F-E-D-K-G-V-K-V-I-V-D-G-K-S-I-L-Y-L-D-G-T-E-L-D-F-V-K-E-G-L-N-E-G-F-K-F-N-N-P-N-V-S-S-E-C-G-C-G-E-S-F-H-V


### FUNCTION Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins ### SEQUENCE -M-R-L-T-S-K-G-R-Y-A-V-T-A-M-L-D-V-A-L-H-S-Q-E-G-P-V-P-L-A-D-I-S-E-R-Q-G-I-S-L-S-Y-L-E-Q-L-F-S-R-L-R-K-N-G-L-V-S-S-V-R-G-P-G-G-G-Y-L-L-G-R-D-A-G-R-I-F-V-A-E-V-I-S-A-V-D-E-S-V-D-A-T-R-C-Q-G-K-E-G-C-Q-G-G-D-R-C-L-T-H-A-L-W-R-D-L-S-E-R-I-T-S-F-L-G-S-I-S-L-E-E-L-V-K-N-Q-E-V-L-D-V-A-D-R-Q-D-S-D-K-R-R-T-P-N-G-R-P-Q-E-T-I-N-V-N-L-R-A


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-T-Y-E-G-E-L-I-A-E-G-L-R-F-G-I-V-A-S-R-F-N-H-A-L-V-D-R-L-V-E-G-A-I-D-C-I-L-R-H-G-G-R-E-E-D-I-T-L-V-R-V-P-G-S-W-E-I-P-V-A-V-G-E-L-A-R-R-E-E-I-D-A-V-I-A-I-G-V-L-I-R-G-A-T-P-H-F-D-Y-I-A-S-E-V-S-E-G-L-A-N-L-S-L-E-L-R-K-P-I-T-F-G-V-I-T-A-D-T-L-E-Q-A-I-E-R-A-G-T-K-H-G-N-K-G-W-E-A-A-L-S-A-I-E-M-A-N-L-F-K-K-L-R


### FUNCTION Structural component of flagellum, the bacterial motility apparatus Part of the rod structure of flagellar basal body ### SEQUENCE -M-A-I-S-F-D-K-A-F-G-I-H-Q-Y-A-L-S-V-R-S-K-R-A-E-V-L-S-S-N-I-A-N-A-D-T-P-G-F-K-A-R-D-I-N-F-S-Q-A-L-E-E-A-Q-H-Q-Q-G-F-G-L-A-T-T-S-E-K-H-F-A-L-Q-S-D-A-P-G-L-T-Q-Y-R-N-P-L-Q-P-D-T-G-D-G-N-T-V-D-V-Q-Q-E-R-S-E-F-L-R-N-S-L-E-Y-Q-T-S-L-E-F-M-N-S-K-I-S-G-L-L-K-A-L-K-G-E-Q


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-K-E-I-L-Q-N-S-A-H-A-S-V-R-M-Q-R-I-S-P-R-K-A-R-L-V-A-D-L-I-R-Y-K-S-A-T-Q-A-I-V-I-L-K-H-T-H-K-K-A-S-E-I-I-L-K-L-L-N-S-A-I-A-N-A-T-N-N-A-G-L-D-A-T-K-L-Y-V-T-T-I-L-V-N-D-G-P-T-L-K-R-F-Q-P-H-S-R-G-R-A-Y-A-I-L-K-R-T-S-H-F-F-I-E-L-T-E-I-N-N-V-E-E-I-N-K-K-G-D-K


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-A-P-F-V-D-D-H-L-M-K-K-V-L-A-I-I-E-N-K-S-P-K-R-P-I-K-T-W-S-R-R-S-T-I-Y-P-E-F-I-G-L-T-F-Q-V-H-N-G-H-A-F-I-D-V-F-V-T-N-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-F-N-G-H-G-A-D-K-G-K-K


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-G-K-G-F-G-F-S-L-G-K-M-K-E-L-A-D-A-F-K-K-A-Q-Q-V-Q-E-G-A-K-Q-V-Q-E-D-L-N-N-M-E-I-E-G-Q-A-Q-G-G-L-V-K-V-W-V-S-G-N-Q-E-P-L-R-A-E-I-A-P-E-A-L-N-E-G-A-E-V-L-S-E-L-V-A-A-A-M-K-D-A-Y-Q-K-S-T-A-A-M-K-E-K-M-E-A-L-T-A-G-L-G-I-P-G-L


### FUNCTION Contributes to virulence and biofilm formation ### SEQUENCE -M-Y-L-Y-T-S-Y-G-T-Y-Q-F-L-N-Q-I-K-L-N-H-Q-E-R-S-L-F-Q-F-S-T-N-D-S-S-I-I-L-E-E-S-E-G-K-S-I-L-K-H-P-S-S-Y-Q-V-I-D-S-T-G-E-F-N-E-H-H-F-Y-S-A-I-F-V-P-T-S-E-D-H-R-Q-Q-L-E-K-K-L-L-H-V-D-V-P-L-S-N-F-G-G-F-K-S-Y-R-L-L-K-P-T-E-G-S-T-Y-K-I-Y-F-G-F-A-N-R-T-A-Y-E-D-F-K-A-S-D-I-F-N-E-N-F-S-K-D-A-L-S-Q-Y-F-G-A-S-G-Q-H-S-S-Y-F-E-R-Y-L-Y-P-I-E-D-H


### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate  forming two phosphate ions ### SEQUENCE -M-G-Y-K-D-L-P-P-G-K-N-P-P-E-D-I-Y-V-V-I-E-I-P-Q-G-S-G-I-K-Y-E-L-D-K-D-T-G-V-I-F-V-D-R-F-L-F-T-A-M-Y-Y-P-F-N-Y-G-F-I-P-Q-T-L-A-D-D-G-D-P-V-D-V-L-V-I-S-R-E-P-V-A-P-G-S-V-M-R-C-R-P-I-G-M-L-E-M-R-D-E-E-G-I-D-T-K-L-I-A-V-P-H-E-K-L-D-P-T-Y-S-D-I-K-T-V-D-Q-L-P-E-I-I-R-E-R-I-K-H-F-F-E-H-Y-K-E-L-E-P-G-K-W-V-K-V-E-N-W-R-G-L-Q-D-A-I-E-E-I-K-K-G-I-E-N-Y-K-K-G-G-K


### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid  by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-E-E-Q-V-L-S-L-L-E-E-L-C-E-D-E-V-V-R-E-D-L-D-I-N-L-R-D-E-G-L-L-D-S-L-G-F-V-E-M-L-V-R-M-E-E-V-F-G-F-A-T-A-P-T-E-V-T-Y-E-E-I-D-T-P-R-R-V-M-A-Y-V-K-K-R-V-A-A-L


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-E-I-K-K-D-A-Q-E-R-M-D-K-S-V-E-A-L-K-N-N-L-S-K-V-R-T-G-R-A-H-P-S-L-L-S-G-I-S-V-E-Y-Y-G-A-A-T-P-L-N-Q-V-A-N-V-V-A-E-D-A-R-T-L-A-I-T-V-F-D-K-E-L-T-Q-K-V-E-K-A-I-M-M-S-D-L-G-L-N-P-M-S-A-G-T-I-I-R-V-P-L-P-P-L-T-E-E-R-R-K-D-L-V-K-I-V-R-G-E-A-E-G-G-R-V-A-V-R-N-I-R-R-D-A-N-N-D-L-K-A-L-L-K-D-K-E-I-S-E-D-E-D-R-K-A-Q-E-E-I-Q-K-L-T-D-V-A-V-K-K-I-D-E-V-L-A-A-K-E-K-E-L-M-E-V


### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-Q-Y-V-D-D-H-L-M-C-D-I-D-G-N-R-L-T-A-A-A-I-L-G-Q-D-G-S-V-W-S-Q-S-A-T-F-P-A-F-K-P-E-E-I-A-A-I-L-K-D-F-D-Q-P-G-T-L-A-P-T-G-L-F-L-G-G-T-K-Y-M-V-I-Q-G-E-A-G-A-V-I-R-G-K-K-G-S-G-G-I-T-V-K-K-T-N-Q-A-L-I-I-G-I-Y-D-E-P-L-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-I-E-Q-G-L


### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-A-Y-V-D-D-H-L-M-C-E-I-E-G-N-H-L-S-A-A-A-I-I-G-H-D-G-S-V-W-A-Q-S-A-T-F-P-Q-L-K-P-E-E-V-T-G-I-L-N-D-F-N-E-P-G-S-L-A-P-T-G-L-Y-L-G-G-T-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-P-G-G-V-T-V-K-K-S-T-L-A-L-L-I-G-I-Y-D-E-P-M-T-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-V-E-Q-G-L


### FUNCTION Probable transcription factor ### SEQUENCE -M-A-S-S-S-M-S-S-S-S-S-W-T-S-K-Q-N-K-M-F-E-R-A-L-A-V-Y-D-K-D-T-P-D-R-W-Q-N-V-A-K-A-V-G-S-K-S-A-E-E-V-K-R-H-Y-D-I-L-V-E-D-L-M-N-I-E-Q-D-L-V-P-L-P-K-Y-K-T-V-D-V-G-S-K-S-R-G-I-D-D-F-D-L-R-L-M-K-N-M-R-I-Q


### FUNCTION Gibberellin-regulated protein that may function in hormonal controlled steps of development such as seed germination, flowering and seed maturation ### SEQUENCE -M-K-K-M-N-V-V-A-F-V-T-L-I-I-S-F-L-L-L-S-Q-V-L-A-E-L-S-S-S-S-N-N-E-T-S-S-V-S-Q-T-N-D-E-N-Q-T-A-A-F-K-R-T-Y-H-H-R-P-R-I-N-C-G-H-A-C-A-R-R-C-S-K-T-S-R-K-K-V-C-H-R-A-C-G-S-C-C-A-K-C-Q-C-V-P-P-G-T-S-G-N-T-A-S-C-P-C-Y-A-S-I-R-T-H-G-N-K-L-K-C-P


### FUNCTION Involved in the transport of copper ### SEQUENCE -M-D-H-G-N-M-P-P-S-S-P-S-S-M-V-N-H-T-N-S-N-M-I-M-M-H-M-T-F-F-W-G-K-N-T-E-I-L-F-S-G-W-P-G-T-S-L-G-M-Y-V-L-C-L-I-V-V-F-L-L-A-V-I-V-E-W-L-A-H-S-S-I-L-R-G-R-G-S-T-S-R-A-K-G-L-V-Q-T-A-V-Y-T-L-K-T-G-L-A-Y-L-V-M-L-A-V-M-S-F-N-G-G-V-F-I-V-A-I-A-G-F-A-V-G-F-M-L-F-G-S-T-A-F-K-N-P-S-D-D-E-K-P-F-E-Q-L


### FUNCTION Heavy-metal-binding protein ### SEQUENCE -M-T-T-K-K-I-E-I-K-V-D-I-D-C-E-K-C-K-H-A-I-M-E-A-V-T-E-L-E-G-V-N-I-V-S-L-D-Q-E-K-S-I-L-T-V-V-G-T-M-D-P-V-C-V-A-E-Q-L-K-K-I-N-K-K-P-V-V-I-S-V-G-P-P-K-K-P-D-P-K-P-D-P-K-K-D-P-C-F-I-P-Y-C-Y-Y-T-P-R-D-M-V-S-V-N-T-Y-E-S-G-S-G-C-T-I-V


### FUNCTION LEA proteins are late embryonic proteins abundant in higher plant seed embryos The function of those proteins is not known ### SEQUENCE -M-S-E-E-Q-L-Q-K-P-I-D-C-A-D-V-K-G-E-A-E-K-I-S-T-T-E-G-G-I-K-A-A-E-D-K-E-K-G-V-V-A-E-A-S-G-E-Q-A-E-G-E-V-N-Q-K-K-V-V-A-N-P-L-K-S-E-G-T-I-T-I-G-E-A-L-E-A-A-V-L-T-A-G-N-K-P-V-E-W-S-D-A-A-A-I-Q-A-A-E-V-R-A-T-G-R-T-N-I-M-P-G-G-V-A-A-S-A-Q-S-A-A-T-L-N-A-R-I-G-S-D-D-T-K-T-T-L-A-D-V-L-T-G-A-S-S-K-L-P-S-D-K-A-A-T-R-K-D-A-E-G-V-T-G-A-E-M-R-N-D-P-H-L-T-T-Y-P-T-G-V-A-A-S-V-A-A-A-A-R-I-N-Q-S-K


### FUNCTION Thionins are small plant proteins which are toxic to animal cells They seem to exert their toxic effect at the level of the cell membrane Their precise function is not known ### SEQUENCE -M-A-T-N-K-S-I-K-S-V-V-I-C-V-L-I-L-G-L-V-L-E-Q-V-Q-V-E-G-K-S-C-C-K-N-T-T-G-R-N-C-Y-N-A-C-H-F-A-G-G-S-R-P-V-C-A-T-A-C-G-C-K-I-I-S-G-P-T-C-P-R-D-Y-P-K-L-N-L-L-P-E-S-G-E-P-N-A-T-E-Y-C-T-I-G-C-R-T-S-V-C-D-N-M-D-N-V-S-R-G-Q-E-M-K-F-D-M-G-L-C-S-N-A-C-A-R-F-C-N-D-G-D-V-I-Q-S-V-E-A


### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-D-H-D-K-T-G-C-Q-S-P-P-E-G-P-K-L-C-T-N-N-C-G-F-F-G-S-A-A-T-M-N-M-C-S-K-C-H-K-D-M-L-F-Q-Q-E-Q-G-A-K-F-A-S-A-V-S-G-T-S-S-S-S-N-I-I-K-E-T-F-T-A-A-L-V-D-I-E-T-K-S-V-E-P-M-T-V-S-V-Q-P-S-S-V-Q-V-V-A-E-V-V-A-P-E-E-A-A-K-P-K-G-P-S-R-C-T-T-C-N-K-R-V-G-L-T-G-F-K-C-R-C-G-S-L-F-C-G-T-H-R-Y-A-D-V-H-D-C-S-F-N-Y-H-A-A-A-Q-E-A-I-A-K-A-N-P-V-V-K-A-E-K-L-D-K-I


### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-D-H-L-M-C-D-I-E-G-T-G-Q-H-L-T-A-A-A-I-L-G-L-D-G-T-V-W-A-K-S-D-K-F-P-E-F-K-P-E-E-M-K-G-I-I-N-E-F-N-E-V-G-T-L-A-P-T-G-L-F-L-G-G-A-K-Y-M-V-L-Q-G-E-A-G-A-V-I-R-G-K-K-G-A-G-G-I-C-I-K-K-T-G-Q-A-M-V-M-G-I-Y-D-E-P-V-A-P-G-Q-C-N-M-I-V-E-R-L-G-D-Y-L-V-D-Q-N-M


### FUNCTION Actin-depolymerizing protein Severs actin filaments ### SEQUENCE -M-A-N-S-A-S-G-L-A-V-N-D-E-C-K-F-K-F-Q-E-L-K-T-R-R-G-F-R-F-I-V-F-K-I-D-D-K-A-M-E-I-K-V-E-R-L-G-Q-T-A-E-G-Y-E-D-F-A-A-T-L-P-A-D-E-C-R-Y-A-V-Y-D-L-D-F-V-T-D-E-N-C-Q-K-S-K-I-F-F-F-S-W-S-P-D-T-A-R-T-R-S-K-M-L-Y-A-S-S-K-D-R-F-R-R-E-L-D-G-I-Q-C-E-I-Q-A-T-D-P-S-E-M-S-L-D-I-I-R-A-R-A-H


### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-V-Y-Q-D-L-L-S-G-D-E-L-L-S-D-S-F-T-Y-K-E-L-E-N-G-V-L-W-E-V-E-G-K-W-V-T-Q-G-P-V-D-V-D-I-G-A-N-P-S-A-E-G-G-E-D-E-S-V-D-D-T-A-V-K-V-V-D-I-V-D-T-F-R-L-Q-E-Q-P-P-F-D-K-K-S-F-V-S-Y-I-K-K-Y-I-K-N-L-T-A-V-L-E-P-E-K-A-D-E-F-K-K-G-V-E-G-A-T-K-F-L-L-S-K-L-K-D-L-Q-F-F-V-G-E-S-M-K-D-D-A-S-V-A-F-A-Y-Y-K-D-G-A-T-N-S-T-F-L-Y-F-S-H-G-L-K-E-I-K-C


### FUNCTION Ubiquitin-like modifier involved in autophagosomes formation With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton Required for selective autophagic degradation of the nucleus  as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production Participates also in membrane fusion events that take place in the early secretory pathway Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy ### SEQUENCE -M-S-S-F-K-K-E-H-P-F-E-K-R-Q-A-E-A-Q-R-I-R-S-K-Y-P-D-R-I-P-V-I-C-E-K-A-D-R-S-D-I-P-D-I-D-K-K-K-Y-L-V-P-A-D-L-T-V-G-Q-F-V-Y-V-I-R-K-R-I-K-L-S-P-E-K-A-I-F-I-F-I-N-N-V-L-P-P-T-A-A-L-M-S-N-I-Y-E-E-Q-K-D-V-D-G-F-L-Y-I-T-Y-S-G-E-N-T-F-G-Q


### FUNCTION The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways ### SEQUENCE -M-A-A-Q-P-V-I-K-V-A-G-L-C-G-S-L-R-K-G-S-Y-N-R-G-L-L-N-A-A-M-E-I-C-K-D-S-I-T-G-M-E-I-E-Y-V-D-I-S-P-L-P-F-L-N-T-D-L-E-V-N-G-T-Y-P-P-V-V-E-A-F-R-K-K-I-E-E-A-D-C-F-L-F-A-S-P-E-Y-N-Y-S-I-T-G-P-L-K-N-A-I-D-W-A-S-R-P-P-N-V-W-A-D-K-A-A-A-M-V-S-A-G-G-G-F-G-G-G-R-S-Q-Y-H-L-R-Q-I-G-V-F-L-D-L-H-F-I-N-K-P-E-F-F-L-N-A-F-Q-Q-P-P-K-F-D-S-D-G-V-L-T-D-E-E-T-K-Q-R-L-R-A-V-L-L-A-L-Q-A-L-A-L-K-L-K-G-K-C-E


### FUNCTION May cover virion head capsid and play a role in capsid stabilization ### SEQUENCE -M-A-N-P-N-F-T-P-S-W-P-L-Y-K-D-A-D-G-V-Y-V-S-A-L-P-I-K-A-I-K-Y-A-N-D-G-S-A-N-A-E-F-D-G-P-Y-A-D-Q-Y-M-S-A-Q-T-V-A-V-F-K-P-E-V-G-G-Y-L-F-R-S-Q-Y-G-E-L-L-Y-M-S-K-T-A-F-E-A-N-Y-T-S-A-S-G-S-V-A-N-A-E-T-A-D-K-L-S-T-A-R-T-I-T-L-T-G-A-V-T-G-S-A-S-F-D-G-S-A-N-V-T-I-E-T-T-S-G-S


### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-M-F-L-F-V-S-L-F-M-F-I-F-K-W-Q-R-L-I-F-I-L-I-S-L-E-F-L-M-L-S-L-F-L-K-F-S-Y-L-L-S-E-M-M-F-F-Y-F-M-C-F-S-V-I-S-S-I-L-G-M-V-V-M-V-G-N-M-K-F-F-G-S-D-N-C-I-F


### FUNCTION Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-N-L-T-L-I-L-F-L-I-G-I-L-G-F-V-L-N-R-K-N-I-I-L-M-L-I-S-I-E-I-M-L-L-A-I-T-F-L-I-L-V-S-S-L-N-I-D-D-I-L-G-Q-T-Y-A-I-Y-I-I-V-V-A-G-A-E-S-A-I-G-L-G-I-L-V-A-F-Y-R-L-R-G-S-V-A-I-E-Y-K


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-S-N-P-N-E-Q-S-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-S-Y-F-F-N


### FUNCTION This b-type cytochrome is tightly associated with the reaction center of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-T-I-D-R-I-Y-P-I-F-T-V-R-W-L-A-I-H-G-L-A-V-P-T-V-F-F-L-G-S-I-S-A-M-Q-F-I-Q-R


### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-T-I-S-I-S-C-L-L-V-S-F-T-G-Y-A-I-Y-T-S-F-G-R-P-S-E-Q-L-R-D-P-F-E-D-H-E-D


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-I-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-G-G-K


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-M-K


### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-S-I-S-G-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-N-K-K-M-K


### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-E-Q-L-R-D-P-F-E-E-H-G-D


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-N-T-K


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-I-K


### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-N-L-V-A-I-F-V-S-C-L-L-V-S-L-T-G-Y-A-L-Y-T-S-F-G-R-P-S-E-G-L-I-D-P-F-D-N-H-E-D


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-L-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-G-G-K-E-N


### FUNCTION Binds 5S rRNA, forms part of the central protuberance of the 50S subunit ### SEQUENCE -M-T-Q-R-L-K-N-L-Y-T-K-T-I-V-P-K-L-T-T-N-F-N-Y-S-N-M-H-E-V-P-K-I-E-K-I-V-I-N-R-G-I-G-D-A-S-Q-N-Q-K-I-V-E-S-S-L-K-E-L-A-M-I-A-G-Q-K-G-V-V-T-R-S-K-K-A-I-A-G-F-K-L-R-Q-Q-M-P-V-G-V-T-V-T-L-R-G-D-R-M-Y-G-F-L-D-R-L-I-H-L-A-L-P-R-V-R-D-F-Q-G-I-S-S-K-S-F-D-K-K-G-N-Y-S-L-G-L-E-E-Q-L-M-F-P-E-I-E-Y-D-K-I-D-Q-V-R-G-M-D-I-S-I-V-T-T-A-K-T-Q-E-E-G-L-A-L-L-K-E-F-G-L-P-F-K


### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-L-D-L-V-K-Y-P-V-I-T-Q-K-T-Y-I-A-L-F-K-D-R-Q-Y-T-F-D-V-D-L-R-L-T-K-P-Q-I-K-K-V-F-E-T-L-F-N-V-D-V-I-S-V-N-T-H-I-P-P-R-Q-K-I-R-V-G-L-A-Q-G-Y-R-P-R-Y-K-R-A-I-I-T-L-K-E-G-Q-S-I-N-Y-S-L-K-N-D-N


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-A-T-L-G-I-I-F-F-A-I-F-F-R-D-P-P-K-V-P-N-K


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-K-S-K-N-H-T-T-H-N-Q-S-R-K-W-H-R-N-G-I-K-K-P-R-S-Q-R-Y-E-S-L-K-G-V-D-P-K-F-L-R-N-M-R-F-A-K-K-H-N-K-K-G-L-R-K-M-Q-T-N-N-A-K-A-M-S-A-R-A-E-A-V-K-A-L-V-K-P-K-E-V-K-P-K-I-P-K-G-V-S-R-K-L-D-R-L-A-Y-I-A-H-P-K-L-G-K-R-A-R-A-R-I-A-K-G-L-R-L-C-R-P-K-A-K-A-K-A-K-D-Q-T-K-A-Q-A-A-A-P-A-S-I-P-A-Q-A-P-K-G-A-Q-A-T-T-K-A-T-E


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-P-R-K-I-E-E-I-K-D-F-L-L-T-A-R-R-K-D-A-K-S-V-K-I-K-K-N-K-D-N-V-K-F-K-V-R-C-S-R-Y-L-Y-T-L-V-I-T-D-K-E-K-A-E-K-L-K-Q-S-L-P-P-G-L-A-V-K-E-P-K


### FUNCTION Thyroid hormone-binding protein Probably transports thyroxine from the bloodstream to the brain ### SEQUENCE -M-A-S-H-R-L-L-L-L-C-L-A-G-L-V-F-V-S-E-A-G-P-T-G-V-D-E-S-K-C-P-L-M-V-K-V-L-D-A-V-R-G-S-P-A-V-N-V-A-V-N-V-F-K-K-A-A-D-E-T-W-A-P-F-A-S-G-K-T-S-E-S-G-E-L-H-G-L-T-T-E-E-E-F-V-E-G-I-Y-K-V-E-I-D-T-K-S-Y-W-K-S-L-G-I-S-P-F-H-E-H-A-E-V-V-F-T-A-N-D-S-G-P-R-H-Y-T-I-A-A-L-L-S-P-Y-S-Y-S-T-T-A-V-V-T-N-P-K-E


### FUNCTION The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity ### SEQUENCE -M-Q-S-L-M-Q-A-P-V-L-I-A-L-G-L-L-F-A-A-P-A-Q-A-H-L-K-K-L-G-S-F-S-W-D-N-C-D-E-G-K-D-P-A-V-I-R-S-L-T-L-E-P-D-P-I-L-I-P-G-N-V-T-V-S-V-V-G-S-T-S-V-L-L-S-S-P-L-K-V-E-L-V-L-E-K-E-V-A-G-L-W-I-K-I-P-C-T-D-Y-I-G-S-C-T-F-E-D-F-C-D-V-L-D-M-L-I-P-T-G-E-P-C-P-E-P-L-R-T-Y-G-L-P-C-H-C-P-F-K-E-G-T-Y-S-L-P-K-S-E-F-V-V-P-H-L-E-L-P-S-W-L-T-T-G-N-Y-R-I-E-S-I-L-S-N-R-G-K-R-L-G-C-I-K-I-A-A-S-L-K-G-V


### FUNCTION Crystallins are the dominant structural components of the vertebrate eye lens ### SEQUENCE -M-S-G-T-L-S-Q-G-S-S-P-A-R-L-T-L-W-E-E-E-N-F-Q-G-R-R-C-E-L-M-S-D-C-S-S-I-R-E-L-S-G-F-R-R-V-R-S-V-K-V-E-S-G-A-W-V-G-F-E-Y-P-D-F-Q-G-Q-Q-F-I-L-E-K-G-D-Y-P-R-S-T-A-W-S-G-S-S-G-Y-R-T-D-Q-L-L-S-F-R-P-L-L-C-A-N-H-S-D-S-R-V-T-L-Y-E-G-E-N-F-Q-G-C-K-F-E-L-S-D-D-Y-P-S-L-P-A-M-G-W-A-S-K-D-V-G-S-L-K-V-T-S-G-A-W-V-G-Y-Q-Y-P-G-F-R-G-Y-Q-Y-V-L-E-Q-D-R-H-S-G-E-F-R-K-Y-S-E-F-G-T-Q-A-H-T-N-Q-L-Q-S-I-R-R-V-Q-H


### FUNCTION Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts It also modulates hydroxyapatite crystal formation on the tooth surface ### SEQUENCE -M-K-I-F-F-F-A-F-I-M-A-L-M-V-A-M-I-K-A-D-S-S-E-E-E-H-R-L-R-F-N-P-R-F-Y-Y-P-N-Q-Q-G-G-Y-I-P-S-Y-P-A-Y-P-Y-P-Y-P-Y-P-V-Q


### FUNCTION Highly potent vasoconstrictor ### SEQUENCE -M-Y-K-L-A-S-C-C-L-L-F-I-G-F-L-N-P-L-F-S-L-P-L-L-D-S-G-E-V-S-L-Q-L-S-A-P-H-E-D-A-P-L-T-S-E-E-L-E-R-A-S-L-L-Q-I-L-P-E-M-L-L-G-A-E-R-G-D-S-L-R-K-A-D-S-S-T-N-I-F-N-P-R-G-N-L-R-K-F-Q-D-F-S-G-Q-D-P-D-I-L-L-S-H-L-L-A-R-I-R-K-P-Y-K-K-R-E-T-P-D-C-F-W-K-Y-C-V


### FUNCTION May be an effector molecule of cytotoxic activity Has antimicrobial activity ### SEQUENCE -M-T-S-R-A-L-L-L-L-A-S-A-L-L-G-T-P-G-L-T-F-S-G-L-N-P-E-S-Y-D-L-A-T-A-H-L-S-D-G-E-Q-F-C-Q-G-L-T-Q-E-D-L-Q-G-D-L-L-T-E-R-E-R-Q-G-I-A-C-W-S-C-R-K-I-L-Q-K-L-E-D-L-V-G-E-Q-P-N-E-A-T-I-N-E-A-A-S-R-V-C-R-N-L-G-L-L-R-G-A-C-K-K-I-M-R-T-C-L-R-L-I-S-R-D-I-L-A-G-K-K-P-Q-E-V-C-V-D-I-K-L-C-K-H-K-A-G-L-I


### FUNCTION Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids ### SEQUENCE -M-E-M-L-Q-G-L-L-L-W-L-L-L-N-V-G-G-V-W-A-S-R-G-P-L-R-P-L-C-R-P-I-N-A-T-L-A-A-E-N-E-A-C-P-V-C-V-T-F-T-T-T-I-C-A-G-Y-C-P-S-M-V-R-V-L-P-A-I-L-P-P-M-P-Q-P-V-C-T-Y-H-E-L-H-F-A-S-I-R-L-P-G-C-P-P-G-V-D-P-M-V-S-F-P-V-A-L-S-C-R-C-G-P-C-R-L-S-N-S-D-C-G-G-P-R-A-Q-P-L-A-C-D-R-P-P-L-P-G-L-L-F-L


### FUNCTION Binds specifically to cytosolic chaperonin ### SEQUENCE -M-S-Q-E-K-I-S-E-I-I-K-D-I-S-A-L-K-T-S-C-E-K-L-N-S-Q-L-D-E-L-I-T-Q-K-V-E-N-E-M-L-L-E-E-V-K-V-L-E-D-D-S-V-L-H-K-L-V-G-L-V-L-V-K-E-E-K-S-K-C-Y-D-T-I-S-R-R-L-Q-Y-I-T-G-E-I-E-N-R-K-K-V-I-T-N-S-E-E-K-L-R-K-L-F-S-D-L-E-A-H-A-G-Q-R-K-I-P-V-P-Q-A


### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-K-V-F-K-D-V-F-T-N-D-E-V-C-S-D-S-Y-V-Q-Q-D-P-F-E-V-P-E-F-R-E-I-A-F-E-V-K-S-N-K-R-I-K-G-N-E-D-Y-G-I-A-D-N-S-E-D-A-V-E-G-M-G-A-D-V-E-H-V-I-D-I-V-D-S-F-Q-L-T-S-T-A-F-S-K-K-E-Y-S-A-Y-I-K-N-Y-M-Q-K-V-A-K-Y-L-E-E-K-K-P-D-R-V-E-I-F-K-T-K-A-Q-P-F-I-K-H-I-L-T-N-F-D-D-F-E-F-Y-M-G-E-S-L-D-M-E-A-G-I-I-Y-S-Y-Y-K-G-E-E-I-T-P-R-F-V-Y-I-S-D-G-L-F-E-E-K-Y


### FUNCTION Probable neurotoxin that inhibits ion channels ### SEQUENCE -M-H-L-S-L-A-R-S-A-V-L-I-L-L-L-L-F-A-L-G-N-F-V-G-V-Q-P-G-Q-I-T-R-D-A-D-H-G-I-N-L-R-S-L-R-K-Q-M-S-R-S-P-L-V-K-G-A-F-C-G-Q-A-C-S-S-V-K-C-P-K-K-C-F-C-H-P-E-E-K-V-C-Y-R-E-M-R-T-K-E-R-D


### FUNCTION May increase intracellular calcium release through the activation of nuclear inositol 1,4,5-trisphosphate receptors  of cardiomyocytes, thereby causing an increase in the contraction frequency of these cells ### SEQUENCE -M-N-T-F-V-V-V-F-L-L-L-T-A-I-L-C-H-A-E-H-A-L-D-E-T-A-R-G-C-N-R-L-N-K-K-C-N-S-D-G-D-C-C-R-Y-G-E-R-C-I-S-T-G-V-N-Y-Y-C-R-P-D-F-G-P


### FUNCTION Necessary for protein translocation in the endoplasmic reticulum and multi-pass membrane protein biogenesis ### SEQUENCE -M-D-Q-V-M-A-W-V-E-P-G-K-Q-F-A-K-D-S-I-R-L-V-K-R-C-T-K-P-D-R-K-E-F-Q-K-I-A-V-A-T-A-I-G-F-A-I-M-G-F-I-G-F-F-V-K-L-I-H-I-P-I-N-N-I-I-V-G-S


### FUNCTION Required for ribosome biogenesis Part of a complex which catalyzes pseudouridylation of rRNA This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 Pseudouridine ### SEQUENCE -M-A-K-T-P-K-K-D-K-T-E-E-K-E-E-H-E-E-S-G-G-N-K-E-D-R-E-R-A-Y-E-V-L-A-T-R-V-N-P-I-A-S-P-L-A-A-R-K-L-T-K-R-L-Y-K-T-V-K-K-A-S-K-E-K-N-I-R-K-G-I-R-D-V-Q-K-F-I-K-K-G-E-R-G-I-V-L-I-A-G-D-T-T-P-I-E-V-Y-C-H-L-P-V-V-C-E-D-A-K-I-P-Y-C-Y-V-P-A-K-Q-D-L-G-E-A-A-G-S-K-R-P-T-C-C-V-L-L-K-P-N-E-S-Y-Q-S-S-Y-D-E-C-L-T-D-V-T-T-L-P-R-P-I


### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-N-F-R-E-E-R-Y-D-T-I-M-F-T-D-S-H-C-P-R-V-V-A-D-F-F-Y-E-V-E-S-R-F-T-T-A-S-S-K-V-D-G-R-L-I-G-A-N-P-S-G-E-G-E-D-D-E-D-V-D-D-T-S-E-R-V-I-D-L-V-H-A-N-G-F-I-S-V-P-Y-D-L-K-S-Y-K-A-Q-L-K-S-Y-L-K-A-I-K-E-R-L-Q-K-T-V-P-D-K-L-P-L-L-E-S-Q-V-N-K-Y-R-K-D-V-F-A-N-F-D-Q-Y-E-C-F-T-G-P-S-T-N-P-E-A-M-V-V-L-M-N-F-V-C-G-R


### FUNCTION Not involved in actin polymerisation, instead functions to stimulate nucleotide exchange on monomeric actin and influence turnover of the small amount of cytosolic actin microfilaments Essential for erythrocytic schizogony ### SEQUENCE -M-V-S-G-V-K-V-S-D-E-C-V-Y-E-F-N-K-L-K-I-K-H-I-H-K-Y-I-I-Y-R-I-E-N-Y-E-E-V-I-V-D-F-L-E-Q-D-N-S-L-K-S-Y-K-D-I-I-I-D-I-R-N-N-L-K-T-T-E-C-R-Y-I-I-A-D-M-P-I-P-T-P-E-G-V-L-R-N-R-I-Y-F-I-F-W-S-P-D-L-A-K-S-K-E-K-M-L-Y-A-S-S-K-E-Y-L-V-R-K-I-N-G-I-F-K-S-L-E-I-T-C-D-L-E-D-F-E-D-E-L-R-T-I-I-L-N-T


### FUNCTION The GINS complex plays an essential role in the initiation of DNA replication ### SEQUENCE -M-T-P-E-Q-C-E-F-I-A-G-N-E-W-I-Q-I-N-P-Q-F-N-L-D-E-L-H-L-I-C-G-D-I-G-P-F-E-A-G-M-P-I-W-V-P-L-W-I-A-V-T-L-R-K-R-R-K-C-T-I-I-P-P-Q-W-L-C-V-E-E-L-K-K-L-V-I-A-E-S-G-T-N-A-F-G-Q-V-P-R-F-Y-L-E-I-A-H-M-F-V-Q-Y-A-K-E-D-L-P-D-S-D-M-I-R-V-Y-V-Q-D-L-W-D-K-R-S-A-K-L-N-N-S-S-T-K-F-L-G-Q-V-E-S-C-H-A-R-M-D-N-I-T-L-M-E-V-A-Y-I-K-R-S-L-I-T-A-S-R-E-I-E-A-L-N-K-S-F-H-E-L-S-S-Q-N-S-S-D-Q-R-Y-V-I-A


### FUNCTION Subunit of the oligosaccharyl transferase  All subunits are required for a maximal enzyme activity ### SEQUENCE -M-S-A-S-V-S-S-K-S-T-V-V-S-S-I-I-S-G-L-L-S-I-V-L-F-G-T-L-R-F-C-S-E-W-F-N-D-S-Q-L-R-V-L-L-G-G-Y-L-F-S-W-V-F-I-L-S-L-T-C-V-S-N-A-E-M-V-V-F-G-Q-D-F-Q-A-K-L-L-P-E-I-I-F-C-L-S-L-T-V-A-A-A-G-L-V-H-R-V-C-A-T-T-S-V-L-F-S-L-V-G-L-Y-F-L-N-R-I-S-T-K-Y-Y-S-V-Q-V-P-S-V-D-A-P-T-T-R-K-G-G-K-K-F-K


### FUNCTION May participate in the coupling of lysosomes to microtubule plus-end-directed kinesin motor ### SEQUENCE -M-S-R-G-N-E-L-V-F-K-A-K-K-T-S-E-K-I-S-E-N-I-H-I-F-A-N-D-P-S-L-A-F-F-R-V-Q-E-H-V-R-K-V-T-P-A-I-F-E-K-R-D-E-V-F-Q-L-Q-N-N-L-Q-G-H-C-Y-D-M-E-Y-G-I-Q-A-L-R-T-I-E-K-S-E-S-I-F-E-N-I-Q-E-M-I-K-A-S-I-F-L-K-Q-Q-L-K-Y-E-E-S-R-K-K-V-K-K-D-S-T-K-S-S-V-Y-K-R-F-S-A-H-L-A-L-D-L-P-D-L-P-D-F-G-G-V-M-R-E-T-S-Q-R-M-E-N-M-I-G-P-G-T-A-T-G-R-T-E-A-Q-A-A-T-S-S-N-P-G-E-L-Q-R-S-Y-T-T-L-H


### FUNCTION Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA ### SEQUENCE -M-S-L-V-I-P-E-K-F-Q-H-I-L-R-V-M-N-T-N-I-D-G-R-R-K-I-M-F-A-L-T-S-I-K-G-V-G-R-R-Y-S-N-I-V-C-K-K-A-D-I-D-L-S-K-R-A-G-E-L-S-D-E-E-V-E-R-L-I-T-I-M-Q-N-P-R-Q-Y-K-I-P-D-W-F-L-N-R-Q-K-D-V-K-D-G-K-Y-S-Q-V-M-A-N-S-L-D-N-K-L-R-E-D-L-E-R-L-K-K-I-R-A-H-R-G-L-R-H-Y-W-G-L-R-V-R-G-Q-H-T-K-T-T-G-R-R-G-R-T-V-G-V-S-K-K-K


### FUNCTION Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA ### SEQUENCE -M-A-L-I-I-P-E-K-F-Q-H-I-L-R-V-M-N-T-N-I-D-G-K-R-K-I-M-F-A-M-T-A-I-K-G-M-G-R-R-Y-A-N-V-V-C-K-K-A-D-V-D-I-T-K-R-A-G-E-L-S-E-D-E-I-E-R-V-I-T-I-M-S-N-P-R-Q-Y-K-I-P-N-W-F-L-N-R-Q-K-D-V-K-D-G-K-Y-S-Q-V-M-S-N-A-L-D-N-K-L-R-E-D-L-E-R-L-K-K-I-R-A-H-R-G-L-R-H-Y-W-G-L-R-V-R-G-Q-H-T-K-T-T-G-R-R-G-R-T-V-G-V-A-K-K-K


### FUNCTION Necessary for the splicing of pre-mRNA ### SEQUENCE -M-A-M-A-N-R-Q-N-R-G-A-K-L-P-P-E-V-N-R-I-L-Y-I-K-N-L-P-Y-K-I-T-T-E-E-M-Y-E-I-F-G-K-F-G-A-V-R-Q-I-R-V-G-N-T-A-E-T-R-G-T-A-F-V-V-Y-E-D-I-F-D-A-K-T-A-C-E-H-L-S-G-Y-N-V-S-N-R-Y-L-V-V-L-Y-Y-Q-A-T-K-A-W-K-R-M-D-T-E-K-A-R-T-K-L-E-D-I-K-E-R-Y-G-I-G-G-D-I-D-K-E-K-E-K-L-G-L-F-T-P-R-R-I


### FUNCTION May have a role in proliferation and/or differentiation ### SEQUENCE -M-A-D-S-G-D-A-G-S-S-G-P-W-W-K-S-L-T-N-S-R-K-K-S-K-E-A-A-V-G-V-P-P-P-A-Q-P-A-P-G-E-P-T-P-P-A-P-P-S-P-D-W-T-S-S-S-R-E-N-Q-H-P-N-L-L-G-G-A-G-E-P-P-K-P-D-K-L-Y-G-D-K-S-G-S-S-R-R-N-L-K-I-S-R-S-G-R-F-K-E-K-R-K-V-R-A-T-L-L-P-E-A-G-R-S-P-E-E-A-G-F-P-G-D-P-H-E-D-K-Q


### FUNCTION May be involved in a redox-related process ### SEQUENCE -M-A-P-R-G-R-K-R-K-A-E-A-A-V-V-A-V-A-E-K-R-E-K-L-A-N-G-G-E-G-M-E-E-A-T-V-V-I-E-H-C-T-S-U-R-V-Y-G-R-N-A-A-A-L-S-Q-A-L-R-L-E-A-P-E-L-P-V-K-V-N-P-T-K-P-R-R-G-S-F-E-V-T-L-L-R-P-D-G-S-S-A-E-L-W-T-G-I-K-K-G-P-P-R-K-L-K-F-P-E-P-Q-E-V-V-E-E-L-K-K-Y-L-S


### FUNCTION Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH At alkaline ambient pH, activates transcription of alkaline-expressed genes ### SEQUENCE -V-C-E-R-H-V-G-R-K-S-T-N-N-L-N-L-T-C-Q-W-N-S-C-R-T-T-T-V-K-R-D-H-I-T-S-H-I-R-V-H-V-P-L-K-P-H-K-C-E-F-C-G-K-S-F-K-R-P-Q-D-L-K-K-H-V


### FUNCTION Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH At alkaline ambient pH, activates transcription of alkaline-expressed genes ### SEQUENCE -E-H-V-C-E-R-H-V-G-R-K-S-T-H-N-L-N-L-T-C-Q-W-G-S-C-N-T-T-T-V-K-R-D-H-I-T-S-H-L-R-V-H-V-P-L-K-P-H-K-C-D-F-C-G-K-A-F-K-R-P-Q-D-L-K-K-H-V-K-N-H


### FUNCTION Necessary for protein translocation in the endoplasmic reticulum ### SEQUENCE -M-D-S-S-V-P-G-G-Q-R-T-L-Q-K-R-R-N-A-Q-L-Q-K-E-K-K-A-N-Q-T-P-A-S-P-R-Q-A-G-F-G-G-S-S-S-S-I-L-K-L-Y-T-D-E-A-N-G-L-R-V-D-P-L-V-V-L-F-L-A-V-A-F-V-F-S-V-V-A-L-H-V-V-A-K-V-S-G-K-I-F


### FUNCTION Negative regulator of sphingolipid synthesis ### SEQUENCE -M-N-V-G-V-A-H-S-E-V-N-P-N-T-R-V-M-N-S-R-G-I-W-L-T-Y-A-L-G-V-G-M-L-H-I-V-L-L-S-I-P-F-F-S-V-P-V-V-W-T-L-T-N-V-I-H-N-F-G-M-Y-V-F-M-H-A-V-K-G-T-P-F-E-T-P-D-Q-G-K-A-R-L-L-T-H-W-E-Q-L-D-Y-G-V-Q-F-T-S-S-R-K-F-F-T-I-S-P-I-I-L-Y-F-L-A-S-F-Y-T-K-Y-D-T-A-H-F-V-I-N-T-A-S-L-L-S-V-L-I-P-K-L-P-Q-L-H-G-V-R-I-F-G-I-N-K-Y


### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-C-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-I-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-Y-N-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-S-K-S-G-E-K-F-Q-C-S


### FUNCTION May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors ### SEQUENCE -M-V-L-D-K-E-E-G-V-P-M-L-S-V-Q-P-K-G-K-Q-K-G-C-A-G-C-N-R-K-I-K-D-R-Y-L-L-K-A-L-D-K-Y-W-H-E-D-C-L-K-C-A-C-C-D-C-R-L-G-E-V-G-S-T-L-Y-T-K-A-N-L-I-L-C-R-R-D-Y-L-R-L-F-G-T-T-G-N-C-A-A-C-S-K-L-I-P-A-F-E-M-V-M-R-A-R-D-N-V-Y-H-L-D-C-F-A-C-Q-L-C-N-Q-R-F-C-V-G-D-K-F-F-L-K-N-N-M-I-L-C-Q-M-D-Y-E-E-G-Q-L-N-G-S-F-E-T-Q-V-Q


### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-C-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-I-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-S-D-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-S-K-S-G-E-K-Y-Q-C-S


### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-C-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-I-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-Y-N-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-P-K-S-G-E-K-F-Q-C-S


### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-C-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-I-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-Y-N-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-S-K-S-G-E-K-S-Q-C-S


### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-C-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-V-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-Y-N-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-S-K-S-G-E-K-F-Q-C-S


### FUNCTION Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal ### SEQUENCE -M-K-C-F-A-Q-I-V-V-L-L-L-V-I-A-F-S-H-G-A-V-I-T-G-V-R-D-R-D-A-Q-C-G-S-G-T-C-C-A-A-S-A-F-S-R-N-I-R-F-C-V-P-L-G-N-N-G-E-E-C-H-P-A-S-H-K-V-P-Y-N-G-K-R-L-S-S-L-C-P-C-N-T-G-L-T-C-S-K-S-G-E-K-Y-Q-C-S


### FUNCTION Induces caspases and apoptosis Counters the protective effect of Bcl-2 ### SEQUENCE -M-E-Q-D-I-Y-S-N-G-S-D-H-M-E-R-M-L-L-F-A-F-L-A-E-S-S-G-C-E-F-Q-E-Q-L-P-S-L-Q-S-Q-G-V-L-C-S-V-K-D-A-L-C-Y-D-S-D-G-E-L-Q-T-D-G-N-R-S-G-H-L-Q-N-G-E-L-V-P-D-P-E-V-N-E-A-I-V-R-T-I-A-A-Q-L-A-E-I-G-D-Q-L-D-K-Q-I-K-A-K-V-V-N-D-L-V-Q-H-F-L-N-E-N-L-P-R-E-E-I-T-R-C-L-S-Q-A-V-E-G-L-A-R-A-I-P-S-D-L-E-Q-E-K-A-M-L-V-L-A-M-L-L-T-K-K-V-A-N-Q-M-P-S-L-L-Q-R-V-F-S-T-T-V-N-Y-I-S-Q-H-F-H-N-Y-I-V-R-M-L-R-E


### FUNCTION Hypotensive neuropeptide that binds cholecystokinin receptors ### SEQUENCE -M-Y-S-G-I-C-S-C-L-F-L-A-V-L-S-S-S-S-L-G-Q-Q-I-S-G-S-Q-H-A-N-P-A-V-T-D-L-E-Q-S-L-L-E-N-H-R-H-T-R-I-P-T-S-G-R-P-I-Q-L-V-D-G-S-I-D-Q-K-A-N-L-G-A-L-L-A-K-Y-L-Q-Q-A-R-R-G-S-T-G-K-A-S-V-M-G-L-Q-N-F-D-P-T-H-R-I-K-D-R-D-Y-M-G-W-M-D-F-G-R-R-S-A-E-E-Y-E-Y-S-S


### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-A-S-Q-Q-M-S-T-N-N-A-Q-M-S-A-Q-Q-A-A-V-L-Q-Q-T-Q-A-Q-Q-L-S-Q-Q-Q-D-F-D-P-V-H-R-F-K-M-L-I-P-P-L-K-D-S-L-Q-N-V-M-T-I-A-S-L-N-F-A-H-N-T-A-I-D-N-G-L-K-T-T-E-K-G-N-D-A-A-V-Q-R-F-D-K-S-L-E-E-F-Y-A-L-C-D-Q-L-E-L-C-L-R-L-A-H-E-C-L-S-Q-S-I-D-S-T-K-H-S-P-N-L-V-P-T-A-T-K-P-D-T-V-Q-T-E-S-L-S-Y-S-Q-Y-L-S-M-I-K-S-Q-I-S-C-A-K-D-I-H-N-A-L-L-E-C-S-K-K-I-A-G-K-G-Q-G-A-C-N


### FUNCTION Antifreeze proteins lower the blood freezing point ### SEQUENCE -M-K-F-S-L-I-A-A-V-A-L-L-A-L-A-Q-G-S-F-A-Q-D-A-A-D-L-E-K-I-T-Q-Y-F-E-N-L-K-N-K-M-T-E-D-V-T-A-F-L-T-N-Q-D-V-A-N-Q-A-Q-T-F-M-Q-E-R-K-T-Q-L-E-P-L-A-T-Q-I-Q-E-Q-L-R-A-A-A-T-K-F-E-E-H-I-T-P-L-A-A-N-V-Q-P-V-V-E-N-F-Q-Q-Q-M-E-A-L-V-Q-K-L-M-E-K-T-R-S-I-S-N


### FUNCTION Interferes with one step of hemostasis ### SEQUENCE -M-G-R-F-I-F-V-S-F-G-L-L-V-V-F-L-S-L-S-G-T-A-A-D-C-P-S-G-W-S-S-Y-D-G-H-C-Y-Q-V-F-S-D-L-K-N-W-D-D-A-E-S-F-C-S-G-Q-H-E-G-S-R-L-A-S-I-H-S-R-E-E-E-A-F-V-G-K-M-A-S-R-T-L-K-Y-T-S-M-W-L-G-L-N-N-P-W-K-E-C-K-W-E-W-S-D-D-T-R-L-D-Y-K-V-W-T-R-R-P-Y-C-T-V-M-V-V-K-T-D-R-I-F-W-F-N-R-G-C-E-K-S-V-S-F-V-C-K-F-K-A-Y-S-E-D-A-A-E


### FUNCTION Virion protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-R-G-C-D-S-I-D-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-F-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V


### FUNCTION Participates in either intracellular transport of viral proteins or intercellular spread of the virus Cellular profilins modulate actin filament dynamics  via direct binding to actin through an actin-binding domain as well as by modulation of other actin-binding proteins In contrast to cellular homologs, the poxvirus profilins seem to bind actin only weakly ### SEQUENCE -M-A-A-E-W-H-K-I-I-E-D-V-S-K-N-N-K-F-E-D-A-A-I-V-D-Y-K-T-K-K-N-V-L-A-A-I-P-N-R-T-F-A-K-I-I-P-G-E-V-I-A-L-I-T-N-R-N-I-L-K-P-R-I-G-Q-K-F-F-I-V-Y-T-N-S-L-M-D-E-N-T-Y-T-M-E-L-L-T-G-Y-A-P-V-S-P-I-V-I-A-R-T-H-T-A-L-I-F-L-M-G-K-P-T-T-S-R-R-E-V-Y-R-T-C-R-D-Y-A-T-N-V-R-A-T-G-N


### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-N-S-L-S-I-F-F-I-V-V-A-T-A-A-V-C-L-L-F-I-Q-G-Y-S-I-Y-E-N-Y-G-N-I-K-E-F-N-A-T-H-A-A-F-E-Y-S-K-S-I-G-G-T-P-A-L-D-R-R-V-Q-D-V-N-D-T-I-S-D-V-K-Q-K-W-R-C-V-V-Y-P-G-N-G-F-V-S-A-S-I-F-G-F-Q-T-E-V-G-L-N-N-T-R-S-I-R-K-F-N-T-M-Q-Q-C-I-D-F-T-F-S-D-V-I-N-I-D-I-Y-N-P-C-V-A-P-N-I-N-N-A-E-C-Q-F-L-K-S-V-L


### FUNCTION Has thioltransferase and dehydroascorbate reductase activities ### SEQUENCE -M-A-E-E-F-V-Q-Q-R-L-A-N-N-K-V-T-I-F-V-K-Y-T-C-P-F-C-R-N-A-L-D-I-L-N-K-F-S-F-K-R-G-A-Y-E-I-V-D-I-K-E-F-K-P-E-N-E-L-R-D-Y-F-E-Q-I-T-G-G-K-T-V-P-R-I-F-F-G-K-T-S-I-G-G-Y-S-D-L-L-E-I-D-N-M-D-A-L-G-D-I-L-S-S-I-G-V-L-R-T-C


### FUNCTION Viral suppressor of RNA silencing which binds specifically to silencing RNAs ### SEQUENCE -M-E-R-A-I-Q-G-S-D-A-R-E-Q-A-Y-S-E-R-W-D-G-G-C-G-G-T-I-T-P-F-K-L-P-D-E-S-P-S-L-I-E-W-R-L-H-N-S-E-E-S-E-D-K-D-N-P-L-G-F-K-E-S-W-S-F-G-K-V-V-F-K-R-Y-L-R-Y-D-G-T-E-A-S-L-H-R-A-L-G-S-W-E-R-D-T-V-N-N-A-A-S-R-F-L-G-F-G-Q-I-G-C-T-Y-C-I-R-F-R-G-S-C-L-T-I-S-G-G-S-R-T-L-Q-R-L-I-E-M-A-I-R-T-K-R-T-M-L-Q-L-T-P-C-E-V-E-G-N-V-S-R-G-S-P-E-G-T-E-A-F-K-E-E-S-E


### FUNCTION The role of the precursor might be to condense the viral prochromatin for encapsidation by virtue of the two basic domains ### SEQUENCE -M-A-R-L-R-R-A-K-R-T-S-Y-R-R-R-R-R-T-T-R-T-R-T-V-V-T-R-T-A-R-S-T-V-R-R-R-G-G-R-I-V-Y-R-T-S-K-T-T-R-V-G-T-R-R-M-R-G-G-F-L-P-L-L-A-P-I-L-A-A-A-I-G-S-I-P-G-I-V-I-A-A-K-Q-K


### FUNCTION Plays a role in the inhibition of host immune response Binds specifically to transporters associated with antigen processing , thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes ### SEQUENCE -M-S-S-R-Y-L-A-A-V-D-D-Y-L-H-H-P-S-P-R-Y-Q-A-H-V-D-L-R-R-E-L-R-A-Y-A-D-E-E-R-R-E-A-A-R-A-I-A-H-P-E-R-P-L-L-P-P-P-A-T-Q-A-A-P-P-Q-P-S-T-R-E-A-A-H-P-S-A-P-T-A-A-S-S


### FUNCTION Inhibits host transcriptional machinery, by producing modifications to the phosphorylation state of the C-terminal domain ### SEQUENCE -M-M-S-H-Q-Q-V-Q-M-D-L-I-L-M-Q-G-I-W-T-S-V-L-K-M-Q-N-Y-S-T-L-L-Q-L-G-S-S-S-S-M-P-Q-R-P-R-L-L-S-R-V-S-Q-R-G-R-L-T-L-N-L-E-S-G-R-W-R-L-S-I-I-I-F-L-E-T-G-T-T-Q-L-V-T-T-I-L-P-S-T-D-Y-L-G-I


### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-N-A-I-T-I-F-F-I-I-L-S-T-V-A-V-C-I-I-I-F-Q-L-Y-S-I-Y-L-N-Y-D-N-I-K-E-F-N-S-A-H-S-A-F-E-F-S-K-S-V-N-T-L-S-L-D-R-T-I-K-D-P-N-D-D-I-Y-D-P-K-Q-K-W-R-C-V-K-L-D-N-D-Y-V-S-V-S-M-F-G-F-K-S-N-G-S-E-I-R-K-F-K-N-L-E-S-C-I-D-Y-T-F-S-Q-S-T-H-S-D-I-K-N-P-C-I-L-Q-N-G-I-K-S-K-E-C-I-F-L-K-S-M-F


### FUNCTION May mediate extracellular or intracellular signaling of cortical neurons during forebrain development ### SEQUENCE -M-S-S-A-W-T-L-S-P-E-P-L-P-P-S-T-G-P-P-V-G-A-G-L-D-V-E-Q-R-T-V-F-A-F-V-L-C-L-L-V-V-L-V-L-L-M-V-R-C-V-R-I-L-L-D-P-Y-S-R-M-P-A-S-S-W-T-D-H-K-E-A-L-E-R-G-Q-F-D-Y-A-L-V


### FUNCTION May be involved in cytochrome c oxidase biogenesis ### SEQUENCE -M-H-P-D-L-S-P-H-L-H-T-E-E-C-N-V-L-I-N-L-L-K-E-C-H-K-N-H-N-I-L-K-F-F-G-H-C-N-D-L-D-R-E-M-R-K-C-L-K-N-E-Y-S-E-R-R-T-R-S-R-E-H-G-A-A-M-R-R-R-L-S-D-P-P-E-E-A-G-R


### FUNCTION Inhibitor of PPP1CA Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction ### SEQUENCE -M-L-S-S-S-A-A-S-C-T-S-P-N-P-D-T-D-N-P-D-K-K-V-R-W-S-S-E-K-R-R-R-A-S-S-T-D-S-E-S-K-T-H-L-D-I-S-K-L-P-R-S-R-R-P-S-R-L-T-V-K-Y-D-R-G-H-L-Q-R-W-L-E-M-E-Q-W-V-D-A-Q-V-Q-E-L-F-Q-G-Q-A-D-T-S-E-P-E-I-D-L-E-A-L-M-E-L-S-T-D-E-Q-R-T-Q-L-E-A-I-L-Q-D-C-P-G-N-R-E-P-F-I-S-E-L-L-S-Q-L-K-R-L-R-R-L-S-R-P-S-K


### FUNCTION Has antibacterial activity ### SEQUENCE -M-K-L-L-L-L-T-L-A-A-L-L-L-V-S-Q-L-T-P-G-D-A-Q-K-C-W-N-L-H-G-K-C-R-H-R-C-S-R-K-E-S-V-Y-V-Y-C-T-N-G-K-M-C-C-V-K-P-K-Y-Q-P-K-P-K-P-W-M-F


### FUNCTION May be essential for the survival of the neurosensory epithelium of the inner ear ### SEQUENCE -M-Q-A-C-M-V-P-G-L-A-L-C-L-L-L-G-S-L-T-E-A-K-P-L-Q-E-Y-D-P-Y-A-E-P-P-A-M-P-Y-W-P-F-S-T-S-D-F-W-N-Y-I-Q-Y-L-Q-T-Q-G-A-Y-P-Q-V-E-D-L-A-R-T-F-F-A-H-F-P-L-G-S-T-L-G-F-H-V-P-Y-Q-E-D


### FUNCTION May be essential for the survival of the neurosensory epithelium of the inner ear ### SEQUENCE -M-Q-P-C-V-L-W-W-L-A-L-G-L-L-L-G-I-P-A-G-A-K-P-T-P-E-E-A-D-P-N-A-Q-P-P-A-M-P-Y-W-P-F-S-T-S-D-F-W-N-Y-V-Q-Y-F-Q-S-Q-G-A-Y-P-Q-I-E-D-M-A-R-T-F-F-A-H-F-P-L-G-S-T-L-G-F-H-V-P-Y-Q-E-D


### FUNCTION Involved in iron-sulfur  cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-K-K-N-T-N-F-T-Q-I-N-N-N-F-Y-R-L-V-D-D-L-F-L-K-I-E-D-N-L-N-F-Y-D-D-K-I-D-I-D-Y-E-V-Q-D-Y-V-M-T-I-T-F-L-N-K-S-I-I-V-V-N-K-Q-E-S-L-R-Q-I-W-L-A-T-K-F-N-A-Y-H-F-N-Y-K-I-D-K-W-I-C-N-R-S-N-K-D-F-W-E-I-F-E-K-S-C-S-I-Q-S-N-E-N-L-I-F-T-A-F-K-R-I-K-K


### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-K-I-H-P-A-Y-S-Q-I-I-A-T-C-S-C-G-N-I-I-E-I-F-S-T-V-N-V-N-L-N-L-D-I-C-A-K-C-H-P-F-Y-T-G-K-Q-R-I-I-D-T-G-G-R-V-E-R-F-K-K-R-F-K-L-I-K-K-D-T-V


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-T-I-N-N-E-N-L-I-W-I-D-L-E-M-T-G-L-N-S-E-I-H-R-I-I-E-I-A-T-V-I-T-D-T-K-L-N-I-I-S-E-G-P-V-I-A-I-H-Q-K-E-E-H-I-V-I-M-D-E-W-N-T-K-I-H-K-K-N-G-L-I-K-R-V-Q-K-S-I-Y-N-E-S-K-A-E-S-K-T-I-F-F-L-K-K-W-V-P-I-Q-S-S-P-I-C-G-N-S-V-Y-Q-D-R-K-F-L-A-R-Y-M-P-N-L-E-N-Y-F-H-Y-R-C-I-D-V-S-T-I-K-E-L-V-N-R-W-C-P-S-F-K-K-I-K-K-Q-N-H-T-A-L-E-D-I-H-E-S-I-I-E-L-N-F-Y-K-K-I-F-F-D-T-I-K-Y-S-K


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-I-F-M-I-H-P-D-Y-S-E-K-V-S-V-I-I-E-K-Y-K-K-I-I-H-H-N-S-G-I-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-I-L-L-N-I-E-T-F-P-K-T-I-S-L-L-E-T-D-F-R-F-N-N-A-V-I-R-N-I-I-I-S-V-K-K-A-I-N-E-P-S-P-V-I-K-L-K-E-E-K-K-D-K-K


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-Y-F-R-R-R-K-F-C-R-F-T-A-E-G-I-Q-E-I-D-Y-K-D-I-A-M-L-K-N-Y-I-T-E-N-G-K-I-V-P-S-R-I-T-G-T-R-A-K-F-Q-R-Q-L-S-R-A-I-K-K-A-R-Y-L-A-L-L-P-Y-T-D-Q-H-H


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-V-I-L-L-S-K-I-K-K-L-G-D-S-G-A-I-V-H-V-K-S-G-Y-A-R-N-F-L-I-P-K-G-K-A-I-L-A-S-K-K-N-I-E-S-F-E-A-Q-R-V-E-L-E-K-E-N-I-S-K-L-L-I-A-Q-S-R-A-E-K-I-K-T-I-K-S-I-T-I-P-S-K-V-G-K-E-G-K-I-F-G-S-I-G-I-R-N-I-I-K-E-M-N-L-L-G-I-K-V-N-K-K-E-I-K-L-P-N-G-V-L-R-Q-V-G-E-H-K-V-I-F-Q-P-H-N-E-V-C-E-Y-F-I-V-N-I-I-S-K-K


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-Q-K-H-L-I-N-N-N-I-K-I-R-I-L-D-S-N-I-K-K-N-S-S-F-F-L-P-Q-Y-A-T-P-G-S-S-G-L-D-L-R-A-S-I-K-K-K-I-S-L-P-S-K-E-V-I-L-V-P-T-G-I-A-I-H-I-D-N-P-Y-I-T-A-L-V-L-P-R-S-G-L-G-H-K-N-G-I-I-L-G-N-L-I-G-L-I-D-S-D-Y-Q-G-E-L-M-I-S-L-W-N-R-S-K-N-I-F-F-I-N-P-Y-D-R-I-A-Q-M-I-F-V-P-I-I-R-P-T-F-S-I-V-D-D-F-E-E-T-V-R-F-G-K-G-F-G-H-S-G-V-Q


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-I-V-I-A-F-D-F-G-L-K-N-I-G-V-A-V-G-E-N-I-L-K-K-G-R-A-L-N-K-L-S-A-K-N-G-S-P-D-W-N-N-I-K-N-L-L-K-I-W-Q-P-K-F-L-V-V-G-L-P-L-N-I-D-G-T-R-Q-D-I-T-K-K-A-E-K-F-A-F-L-L-K-Y-K-F-N-I-F-V-Y-L-H-D-E-R-L-S-T-K-E-A-K-S-L-I-F-K-K-N-G-F-K-V-L-K-K-E-K-I-H-S-V-A-A-V-I-I-L-E-S-W-F-N-Q-N-L-Y


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-S-R-G-V-N-K-V-I-L-I-G-H-L-G-Q-D-P-E-V-R-Y-M-P-N-G-N-A-V-V-N-M-T-L-A-T-S-E-N-W-K-D-K-N-T-G-E-N-K-E-K-T-E-W-H-R-I-V-L-F-G-K-L-A-E-I-A-G-E-Y-L-R-K-G-S-Q-V-Y-I-E-G-S-L-Q-T-R-K-W-Q-D-Q-N-G-L-E-R-Y-T-T-E-V-I-V-N-I-G-G-T-M-Q-M-L-G-N-R-N-S-N-S-H-N-V-T-L-N-E-N-N-N-I-V-K-T-K-K-I-E-I-N-N-S-P-K-K-I-E-K-I-D-S-S-E-I-D-F-D-D-E-I-P-F


### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-N-I-S-D-K-A-Q-N-H-F-I-S-L-L-S-K-E-P-I-G-T-Q-I-R-V-F-I-I-N-P-G-T-Q-N-A-E-C-G-V-A-Y-C-T-E-D-D-V-E-N-H-D-I-K-L-N-Y-N-H-F-F-V-Y-V-D-R-S-I-I-S-F-L-K-N-S-E-I-D-L-I-V-D-N-V-G-S-Q-L-T-F-K-A-P-Y-A-K-Q-N-Y-S-K-N-T-A-S-S-L-K-E-R-I-E-N-F-L-N-N-N-I-N-P-Q-L-S-M-H-G-G-K-V-H-L-I-Q-I-S-Q-N-N-T-A-L-I-K-F-T-G-G-C-N-G-C-S-M-I-G-T-T-L-K-E-I-V-E-K-K-I-L-S-F-F-P-E-I-K-K-V-I-D-Q-T-D-H-L-H-G-N-H-S-F-Y


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine  at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-N-Y-T-V-L-V-T-G-S-A-Y-G-T-Q-N-A-S-T-A-F-L-F-C-Q-S-L-I-K-M-S-H-I-L-N-S-V-F-F-Y-C-D-G-V-L-N-A-N-N-F-N-K-P-S-V-D-E-F-D-L-L-S-A-W-K-Q-L-N-E-K-N-K-V-K-L-Y-V-C-V-S-A-A-S-R-R-G-V-I-E-D-E-K-I-S-N-T-K-I-K-N-G-N-F-A-S-F-F-Q-S-S-G-L-L-E-L-A-Y-S-I-K-I-S-D-R-I-I-Q-F


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine  at tRNA wobble positions ### SEQUENCE -M-E-K-I-A-F-V-F-S-H-A-P-H-G-T-S-F-G-K-E-G-L-D-V-I-L-G-V-S-S-I-I-K-K-I-S-L-F-F-I-G-D-G-V-L-Q-I-L-K-H-S-K-S-E-N-I-L-A-R-N-Y-T-S-S-F-R-I-L-S-I-Y-D-I-K-N-F-Y-C-C-K-S-S-L-I-D-R-G-L-Y-S-H-N-Q-F-I-L-K-V-N-I-L-N-S-Y-F-F-R-I-K-L-D-D-H-D-A-I-I-N-F


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine  at tRNA wobble positions ### SEQUENCE -M-L-H-T-L-M-K-S-P-F-E-T-N-I-S-F-F-S-G-M-L-K-K-T-D-D-F-L-A-L-Q-D-G-V-L-I-A-L-I-D-N-I-F-L-K-K-I-T-F-S-S-E-N-L-Y-V-I-K-E-D-V-Y-A-R-G-I-H-K-N-I-S-S-S-F-I-L-I-S-Y-I-D-F-V-N-L-T-L-K-N-K-K-Q-I-I-W


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-V-N-Q-L-V-R-K-P-R-L-R-K-I-V-K-T-N-V-P-A-L-E-G-S-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-T-A-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-I-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-S-L-D-C-A-G-V-K-E-R-K-K-G-R-S-K-Y-G-V-K-K-A-K-V


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-R-I-R-I-R-L-K-A-F-D-H-R-L-I-D-Q-S-T-A-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-R-F-T-I-L-I-S-P-H-V-N-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-L-I-D-I-V-E-P-T-E-K-T-V-D-A-L-M-R-L-D-L-A-A-G-V-D-V-Q-I-S-L-G


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-S-Q-E-R-F-L-K-V-L-L-S-P-H-I-S-E-K-S-S-I-S-M-E-K-F-N-T-V-V-L-K-V-S-R-N-T-T-K-N-E-I-K-F-A-V-Q-N-L-F-N-I-Q-V-E-S-V-K-T-V-Y-V-K-G-K-K-K-R-Q-S-N-R-I-I-Y-R-S-D-W-K-K-A-Y-I-K-V-K-K-G-Q-N-L-D-F-M-S-N-I-E


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-V-S-L-L-K-K-V-E-K-A-V-K-I-N-D-K-K-P-L-K-T-W-S-R-R-S-T-V-F-P-N-M-V-G-L-T-I-S-V-H-N-G-R-H-H-I-P-I-F-I-T-E-E-M-V-G-H-K-L-G-E-F-S-L-T-R-T-Y-R-G-H-T-A-D-K-K-V-K-K-R


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-L-A-Q-H-R-Q-A-R-C-S-A-Q-K-I-R-L-I-A-D-L-I-R-G-K-K-V-P-K-A-L-N-I-L-N-F-N-N-K-K-A-A-I-L-V-K-K-V-L-E-S-A-L-A-N-A-E-H-N-D-G-L-D-V-D-Q-L-R-I-K-N-I-F-V-D-E-G-S-T-M-K-R-M-M-P-R-A-K-G-R-A-D-R-I-L-K-R-T-S-H-I-T-V-I-V-S-D-R


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-M-H-K-G-R-N-R-G-L-A-F-G-A-N-V-S-F-G-L-F-G-L-K-A-I-D-R-G-R-L-T-A-R-Q-I-E-S-A-R-R-A-I-T-R-Y-I-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-Q-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-I-L-Y-E-M-D-G-V-S-E-E-E-S-R-E-A-F-K-L-A-A-A-K-L-P-I-K-T-T-F-V-T-K-M-V-M


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-K-E-K-I-R-T-L-Q-G-R-V-T-S-N-K-M-N-K-S-A-V-V-A-I-E-R-F-V-K-H-P-I-Y-G-K-F-V-K-K-T-T-K-L-H-I-H-D-E-K-N-E-C-S-I-G-D-L-I-E-I-R-E-S-R-P-I-S-K-T-K-S-W-I-L-V-K-I-L-E-K-N-I-F


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-E-Q-T-I-L-N-V-A-D-N-S-G-A-R-S-A-M-C-I-K-V-L-G-G-S-R-R-R-Y-A-R-I-G-D-I-I-K-I-T-I-K-E-A-I-P-R-G-K-V-K-K-G-E-V-L-K-A-V-V-V-R-T-K-K-G-V-R-R-S-D-G-S-I-I-R-F-D-N-N-A-C-V-V-L-N-N-N-E-Q-P-V-G-T-R-I-F-G-P-V-T-R-E-L-R-I-E-K-F-M-K-I-I-S-L-A-P-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-L-K-L-R-R-N-D-E-I-I-I-L-T-G-K-D-K-G-K-K-G-I-I-K-N-I-L-S-S-N-K-A-I-V-N-G-L-N-L-V-K-K-H-Q-K-P-L-P-S-Q-N-K-N-G-G-I-L-E-K-E-A-P-I-Q-I-S-N-I-A-I-F-N-P-E-L-K-K-A-D-R-I-G-F-R-F-E-E-G-K-K-V-R-F-F-K-S-N-K-K-T-I-K


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-T-F-Y-D-Y-Y-K-S-K-I-V-K-K-L-M-M-E-L-N-Y-S-S-I-M-Q-V-P-K-I-D-K-I-T-L-N-M-G-V-G-A-A-S-S-D-K-K-V-L-D-N-A-V-L-D-L-T-A-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-V-A-G-F-K-I-R-Q-G-Y-P-I-G-C-K-V-T-L-R-G-K-R-K-W-D-F-F-E-R-L-I-V-I-A-I-P-R-I-R-D-F-R-G-L-S-T-N-S-F-D-G-K-G-N-Y-S-L-G-I-R-E-Q-I-I-F-P-E-I-D-Y-D-K-I-D-R-V-R-G-L-D-I-T-I-T-T-T-A-N-S-D-H-E-A-R-L-L-L-S-S-F-N-F-P-F-R-K


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-E-V-K-R-V-K-L-A-N-K-F-Y-A-Q-R-I-A-L-K-N-T-I-T-N-L-K-L-S-E-E-E-R-W-D-A-V-L-K-L-Q-I-F-P-R-D-S-S-P-S-R-Q-R-N-R-C-R-Q-T-G-R-P-H-A-F-L-R-K-F-G-L-S-R-I-K-V-R-E-A-A-M-K-G-E-I-P-G-L-K-K-A-S-W


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-R-P-I-L-I-P-E-G-I-K-I-E-L-N-L-Q-S-I-S-I-K-G-K-Y-G-Y-L-S-R-I-I-H-D-A-V-K-V-E-C-L-N-N-K-I-T-F-S-I-R-S-G-F-S-D-A-W-A-Q-A-G-T-S-R-A-L-V-N-S-M-I-I-G-V-S-K-K-F-S-K-K-L-Q-F-S-G-V-G-Y-R-V-S-L-T-K-G-N-I-V-N-M-S-L-G-Y-S-H-P-I-V-Y-S-L-P-P-Y-I-E-A-E-N-P-S-P-T-E-I-V-I-K-G-V-D-K-Q-L-V-G-Q-I-A-A-N-L-R-S-Y-R-R-P-E-P-Y-K-G-K-G-I-R-Y-S-N-E-V-V-H-M-K-E-A-K-K-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-M-F-Y-R-N-K-K-I-I-S-R-T-R-R-L-L-K-A-R-C-K-I-K-S-L-G-A-I-R-L-V-V-H-R-T-S-R-H-M-Y-A-Q-I-I-S-S-E-S-K-V-L-A-F-A-S-T-L-E-S-K-I-K-S-D-L-K-Y-T-G-N-K-E-A-A-E-I-V-G-K-I-I-A-K-R-A-L-L-K-G-I-S-N-V-S-F-D-R-S-G-F-K-Y-H-G-R-I-K-K-L-A-D-S-A-R-N-F-G-L-K-F


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-N-I-E-K-K-N-N-S-E-L-Q-E-K-L-I-T-V-N-R-V-S-K-T-V-K-G-G-R-I-F-S-F-T-A-L-T-V-V-G-N-G-E-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-N-M-V-T-I-P-L-V-N-K-T-L-Q-H-S-L-K-G-S-H-T-G-S-N-I-F-M-K-P-A-S-D-G-T-G-I-I-A-G-G-A-M-R-A-V-L-E-V-A-G-I-H-N-V-L-A-K-T-Y-G-S-T-N-P-I-N-V-V-R-A-T-M-N-G-L-T-N-M-K-S-P-E-M-I-A-A-K-R-N-K-L-I-E-D-I-L-G


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-S-P-S-L-G-S-R-K-N-H-K-R-L-G-R-G-I-G-S-G-F-G-K-T-A-G-R-G-H-K-G-Q-K-S-R-S-G-G-H-V-N-R-G-F-E-G-G-Q-M-P-I-Y-R-R-I-P-K-F-G-F-N-S-R-K-K-N-I-T-A-E-V-R-L-S-D-I-S-K-L-S-T-D-I-I-D-L-K-V-L-K-K-E-N-I-I-N-K-N-I-K-Y-V-K-I-I-L-S-G-K-L-E-V-A-L-T-L-H-G-L-R-V-T-R-G-A-R-L-A-I-E-N-Y-G-G-K-I-E-G


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-E-H-K-H-A-L-I-A-L-T-S-I-Y-G-I-G-K-K-R-S-K-I-I-C-F-N-A-N-I-A-E-N-S-K-I-S-D-L-K-E-E-E-I-E-L-L-R-E-N-V-A-K-Y-V-T-E-G-D-L-R-R-E-K-T-L-N-I-K-R-L-I-D-L-N-C-Y-R-G-L-R-H-R-R-S-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-C-K-G-P-R-K-A-I-K-K


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-V-K-N-S-S-V-R-T-R-K-R-V-K-K-Q-I-T-D-G-I-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-G-W-A-T-S-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-I-A-A-E-R-C-A-E-I-V-K-D-Y-G-I-K-N-L-E-V-M-V-K-G-P-G-P-G-R-E-S-T-I-R-A-L-N-A-A-G-F-R-I-T-N-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-V-L-K-I-L-H-Y-P-D-Q-R-L-R-L-I-A-K-P-V-E-K-I-T-K-E-I-Y-K-I-T-N-N-M-I-D-T-M-Y-Q-E-E-G-I-G-L-A-A-T-Q-V-N-I-Q-L-Q-I-I-V-I-H-K-I-H-A-I-E-K-N-L-I-L-I-N-P-K-I-I-E-K-K-G-S-I-S-I-E-E-G-C-L-S-I-P-E-Y-R-A-F-V-P-R-F-N-Y-I-K-I-Q-A-I-N-L-N-G-N-T-V-E-I-E-A-D-S-I-L-S-I-C-I-Q-H-E-I-D-H-L-N-G-K-L-F-I-D-Y-L-S-E-L-K-R-E-R-I-L-K-K-L-I-K-L-K-K-R-I-K


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-T-K-G-G-L-G-N-L-M-K-Q-A-Q-Q-M-Q-E-K-M-A-K-V-Q-E-E-I-A-K-M-E-V-T-G-E-A-G-A-G-L-V-K-V-T-I-N-G-A-H-N-C-R-R-V-E-V-D-P-S-L-L-K-D-D-K-D-M-L-E-D-L-A-A-A-A-F-N-D-A-T-R-R-I-S-E-V-Q-K-K-K-M-S-A-I-S-T-G-M-Q-L-P-T-G-F-N-I-P-I


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-K-S-N-S-V-L-I-P-M-V-V-E-Q-H-S-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-E-R-I-I-F-I-T-G-T-I-E-D-N-M-A-S-S-I-V-A-Q-M-L-F-L-E-A-E-S-L-D-K-D-I-F-L-Y-I-N-S-P-G-G-I-I-T-S-G-M-S-I-Y-D-T-M-Q-F-I-K-P-D-V-N-T-I-C-I-G-Q-A-C-S-M-A-A-F-L-L-S-S-G-T-K-G-K-R-S-C-L-P-N-A-R-I-M-I-H-Q-P-L-G-G-Y-Q-G-Q-A-S-D-I-A-I-H-A-E-E-I-N-K-M-K-K-K-L-N-K-L-M-S-L-N-T-G-Q-S-I-K-K-I-N-K-D-T-E-R-D-C-F-L-S-A-H-E-S-I-K-Y-G-L-I-D-L-I-L-T-Q-R


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine ### SEQUENCE -M-L-K-N-N-H-T-K-K-L-Y-E-K-I-E-K-D-T-E-G-Y-L-K-K-A-A-D-W-S-I-E-L-A-K-E-I-A-K-K-E-K-I-V-L-T-N-D-H-W-T-V-I-N-F-I-R-K-F-Y-F-K-F-N-I-T-P-S-M-R-M-L-I-K-S-I-E-K-K-I-G-L-K-K-S-N-S-I-Y-L-F-R-L-F-P-E-G-P-A-K-Q-A-S-K-I-A-G-I-P-K-P-S-R-C-L


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-I-I-K-P-N-F-R-R-K-A-R-A-C-A-L-Q-M-L-Y-S-W-E-I-S-Q-N-N-I-K-D-S-A-I-E-F-L-K-E-K-N-K-K-N-I-D-I-I-Y-F-Y-E-L-I-I-G-I-T-Y-N-C-R-S-I-D-D-L-M-K-P-Y-L-S-R-S-L-K-E-L-G-Q-I-E-K-A-I-L-R-I-S-F-Y-E-L-Y-K-R-K-D-I-P-Y-K-V-S-I-N-E-G-I-E-L-A-K-L-F-G-S-E-D-S-H-K-F-I-N-G-V-L-D-K-A-A-L-K-I-K-R


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-K-K-K-N-N-I-I-L-T-I-Q-K-N-C-K-N-T-K-N-I-P-K-K-Y-I-F-E-K-W-I-K-K-V-L-Y-K-K-K-N-V-N-L-I-N-I-R-I-V-D-E-R-E-M-K-N-I-N-L-K-Y-R-G-K-N-K-S-T-N-I-L-S-F-K-F-D-L-F-I-N-K-N-Q-T-L-L-G-D-L-V-L-C-K-K-I-I-E-K-E-S-L-K-Y-Q-K-T-L-E-S-R-W-A-H-M-I-I-H-G-T-L-H-L-L-G-Y-D-H-K-N-K-K-E-K-K-I-M-E-K-I-E-N-K-I-M-L-F-L-N-Y-E-K-P-Y-F-M-K-S-S


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly extracellular ### SEQUENCE -M-K-M-L-K-I-F-L-L-F-L-L-F-W-L-Q-C-S-L-W-I-G-K-N-G-I-L-D-Y-I-K-I-Y-K-K-I-I-V-Q-K-K-K-N-E-D-F-Q-I-R-N-N-Q-L-I-L-E-I-E-R-L-N-N-A-I-K-N


### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-I-I-G-D-E-I-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-V-N-A-P-K-E-V-S-V-H-R-E-E-I-Y-Q-R-I-Q-A-E-K-K-Q-K-K-S


### FUNCTION Activates ribosomal RNA transcription Plays a direct role in upstream activation of rRNA promoters ### SEQUENCE -M-S-E-E-S-M-D-T-G-F-L-V-I-N-T-K-D-K-Q-D-K-T-V-K-K-P-L-R-I-L-I-K-K-S-L-E-N-Y-F-L-H-L-D-K-S-Q-C-V-S-N-L-Y-Q-L-V-L-S-E-L-E-Q-P-L-L-D-I-I-M-Q-H-T-R-G-N-Q-T-R-A-A-S-I-M-G-I-N-R-S-T-L-R-K-K-L-K-R-Y-G-M-N


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-T-N-I-I-Q-E-I-E-Q-E-Q-L-K-E-N-I-P-H-F-R-P-G-D-T-V-E-V-K-V-W-V-I-E-G-S-K-K-R-L-Q-S-F-E-G-I-V-I-S-I-K-N-R-S-L-N-S-S-F-T-V-R-K-V-S-N-G-E-G-I-E-R-V-F-Q-T-H-S-Y-S-I-D-S-I-F-V-K-R-K-G-K-V-R-K-A-K-L-Y-Y-L-R-T-R-T-G-K-S-A-R-I-K-E-R-I-E


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-N-I-F-L-K-K-P-L-H-P-I-L-I-G-K-I-G-K-A-Y-G-I-L-G-W-V-K-F-F-S-F-T-E-N-K-E-K-I-F-S-Y-F-P-W-F-I-L-K-K-K-W-E-I-I-H-V-D-K-W-K-K-H-N-N-N-F-I-I-H-I-E-N-I-L-D-R-S-T-V-S-K-F-T-N-L-E-I-F-I-D-K-S-I-L-P-I-L-K-E-D-E-Y-Y-W-N-D-V-I-D-C-K-V-F-N-S-R-K-E-Y-L-G-K-V-I-N-L-I-R-N-Q-N-N-D-V-L-I-I-R-N-N-L-K-K-N-N-F-K-K-I-M-I-P-F-I-H-K-K-I-V-K-Y-I-N-V-K-H-K-I-I-T-V-I-W-N


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-S-L-K-L-N-D-I-K-R-N-W-F-Y-V-D-A-T-N-K-I-L-G-R-F-A-S-A-I-S-I-R-L-R-G-K-H-K-I-E-Y-T-P-H-L-D-T-G-D-Y-I-I-V-L-N-A-S-K-I-L-V-T-G-Q-K-K-I-N-K-V-Y-Y-H-H-T-G-Y-I-G-G-I-K-Q-L-R-F-E-E-I-M-L-K-N-P-A-K-V-I-E-I-A-V-K-G-M-L-P-K-G-S-L-G-R-S-M-F-K-K-L-K-V-F-S-N-E-N-H-D-H-I-A-Q-C-P-Q-F-L-N-I


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-M-S-G-G-K-Q-Y-R-V-K-K-N-Q-I-I-Q-L-E-K-L-N-N-S-P-G-S-I-I-E-F-D-K-I-L-M-I-S-A-K-K-E-V-K-I-G-E-P-F-L-K-G-T-K-I-K-A-H-V-E-N-H-G-R-L-K-K-I-K-I-I-K-F-N-R-R-K-H-Y-K-K-K-Q-G-H-R-Q-Y-F-T-N-V-K-I-L-D-I-N-N-F-N-G-K


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-I-N-L-I-P-M-T-V-R-G-A-E-K-L-R-E-E-L-E-Q-L-K-N-V-K-R-P-R-I-T-V-Q-I-A-E-A-R-K-H-G-D-L-K-E-N-A-E-Y-H-S-A-R-E-E-Q-S-F-C-E-G-R-I-Q-E-I-E-S-K-L-S-N-S-Q-I-I-D-I-T-K-I-S-N-D-G-R-V-V-F-G-S-T-V-T-I-L-N-I-K-N-N-A-V-F-T-Y-Q-I-V-G-D-D-E-S-D-F-K-K-N-L-I-S-I-N-S-P-M-S-R-G-L-I-G-K-T-V-N-T-I-A-I-I-H-T-P-S-G-N-V-K-Y-K-I-L-K-I-D-Y-I


### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-Y-L-F-F-L-I-F-L-I-F-I-S-F-S-L-I-F-L-I-L-L-Q-S-G-K-G-F-N-N-T-I-H-L-N-T-S-N-N-F-N-F-F-N-S-V-G-S-G-G-F-I-K-N-I-I-G-F-F-A-G-F-F-L-I-F-S-I-I-L-C-N-I-N-D-K-K-V-N-S-D-V-F-L-E-K-N-T-Q-K-K-T-I-N-E-K-K-E-Q-K-I-L-N-S-E-L-P-L


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-D-K-L-F-N-R-S-F-R-I-A-Q-E-L-Q-K-N-I-A-F-I-I-Q-H-S-L-K-D-P-R-I-K-T-I-I-T-V-S-E-V-R-L-S-K-D-L-S-Y-A-Q-V-F-V-S-F-L-E-T-N-S-N-L-T-V-K-K-V-L-I-L-L-N-R-A-S-G-Y-I-R-K-L-L-C-K-K-M-N-L-R-I-I-P-I-I-V-F-F-H-D-D-S-F-F-K-G-N-K-I-S-K-L-L-N-I-L-T-E-K-N-N-I-T-L


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-G-I-M-T-I-K-E-T-I-L-K-Y-G-K-N-E-K-N-T-G-K-T-D-V-Q-I-A-L-L-T-N-Q-I-N-H-L-Q-L-H-F-S-Q-H-K-K-D-H-C-S-R-R-G-L-L-K-M-V-S-K-R-R-K-L-L-N-Y-L-K-K-K-N-I-S-C-Y-T-K-L-I-E-S-L-N-L-R-R


### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-Q-I-N-K-L-Q-V-E-A-I-K-S-G-S-V-I-D-H-I-P-A-H-I-G-F-K-L-L-S-L-F-R-F-T-E-T-E-K-R-I-T-I-G-L-N-L-P-S-Q-K-L-D-K-K-D-I-I-K-I-E-N-T-F-L-S-D-D-Q-I-N-Q-L-A-I-Y-A-P-C-A-T-V-N-Y-I-E-K-Y-N-L-V-G-K-I-F-P-S-L-P-K-K-I-D-R-I-L-I-C-P-N-S-N-C-A-S-H-N-H-F-I-T-S-S-F-I-F-T-K-D-I-N-N-E-I-N-L-K-C-Q-Y-C-E-K-E-F-A-K-N-I-V-L


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-N-N-V-E-K-K-I-K-K-I-I-S-K-I-L-N-I-K-V-E-K-I-L-N-N-A-S-F-L-D-D-L-S-A-D-S-L-D-I-V-E-L-I-M-A-I-E-E-E-F-D-I-E-I-S-D-E-D-A-E-K-L-N-T-V-Q-K-S-I-D-Y-I-N-N-K-N-K-K


### FUNCTION Structural component of flagellum, the bacterial motility apparatus Part of the rod structure of flagellar basal body ### SEQUENCE -M-F-D-K-I-N-K-T-L-D-F-N-Q-N-L-L-N-L-Y-A-K-R-Q-E-I-L-S-S-N-I-A-N-A-D-T-P-N-Y-K-A-M-D-I-N-F-K-D-E-M-D-K-I-T-K-K-S-N-L-D-I-T-L-T-K-T-S-S-H-H-L-N-P-R-K-K-N-F-F-I-F-E-V-K-P-I-T-S-K-E-I-Q-S-N-G-N-T-V-D-M-N-R-E-R-I-E-F-I-K-N-T-L-K-Y-E-E-N-L-V-F-I-K-N-E-I-K-N-I-M-N-V-L-K-G


### FUNCTION Required for the efficient initiation of filament assembly ### SEQUENCE -M-K-K-L-I-N-I-I-K-D-I-K-E-N-L-M-S-L-Q-N-L-M-H-Q-E-Y-D-N-L-L-K-S-K-I-N-I-K-K-I-K-L-I-I-E-E-K-E-F-F-L-R-K-I-A-S-L-K-K-E-K-S-F-L-E-K-R-Y-N-I-F-P-P-Y-L-Q-F-N-E-L-N-L-H-W-D-E-I-I-S-I-C-F-L-L-K-K-K-N-I-K-N-K-I-I-L-N-E-K-F-Y-L-N-Q-R-F-L-N-T-F-Q-K-Y-R-L-N-Q-N-N-T-T-Y-G-V-D-G-H-L-E-N


### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-A-L-L-D-F-F-L-S-R-N-K-N-T-A-H-V-A-K-E-R-L-Q-I-I-V-A-E-Q-R-K-F-K-S-E-P-D-Y-L-P-Q-L-K-R-E-I-L-S-V-I-C-K-Y-V-N-I-D-P-H-M-V-T-I-Q-L-E-Q-K-N-E-D-I-S-V-L-E-L-N-I-I-L-P-D


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-T-K-E-D-N-I-E-M-Q-G-I-V-I-D-T-L-P-N-T-M-F-R-V-E-L-E-N-K-H-V-I-T-A-H-I-S-G-K-M-R-K-N-Y-I-R-I-L-T-G-D-K-V-T-I-E-L-T-P-Y-D-L-T-K-G-R-I-I-F-R-S-R


### FUNCTION Low-potential electron donor to a number of redox enzymes ### SEQUENCE -M-K-K-I-G-I-F-F-G-S-D-T-G-N-T-E-K-A-A-E-L-I-H-K-K-I-G-S-N-I-S-M-L-Y-D-I-S-N-V-S-K-K-D-F-E-S-F-D-H-L-I-L-G-V-P-T-W-Y-Y-G-E-I-Q-C-D-W-D-D-F-L-P-I-L-K-K-I-N-F-L-H-K-T-V-A-L-F-G-C-G-D-Q-E-D-Y-A-E-Y-F-C-D-A-L-G-L-I-Y-Q-V-L-K-K-N-N-A-K-I-V-G-K-W-P-T-I-E-Y-N-F-E-S-Y-K-A-L-L-N-K-D-Y-F-V-G-L-V-L-D-E-A-R-Q-P-E-K-T-E


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-S-I-I-G-I-G-T-D-I-I-E-I-F-R-I-K-N-I-V-Y-N-F-K-D-K-L-A-E-R-I-L-S-V-Q-E-L-E-K-Y-K-V-N-K-N-P-I-K-F-L-A-K-R-F-A-V-K-E-A-A-S-K-A-L-G-T-G-I-S-Y-G-I-K-F-N-Q-I-E-L-Y-N-N-N-L-G-K-P-K-L-R-F-L-K-Y-A-L-Q-K-S-E-E-M-K-C-K-S-I-F-V-S-I-S-D-E-K-L-Y-A-C-A-L-V-I-L-E-K


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-Y-K-K-K-R-C-L-K-S-S-I-I-C-K-N-K-K-A-Y-Y-N-Y-F-I-E-E-V-F-Q-S-G-L-V-L-M-G-W-E-V-K-S-I-R-L-G-Q-V-N-I-I-E-S-Y-I-N-N-D-N-L-N-E-M-Y-L-Y-N-S-I-V-Q-P-L-H-T-S-S-N-Y-V-S-C-D-S-S-R-K-R-K-L-L-L-H-K-N-E-I-Q-Y-L-C-N-K-K-N-K-I-G-S-T-L-V-A-L-S-L-F-W-E-K-S-W-C-K-L-N-F-G-L-A-K-G-K-T-K-I-D-K-R-A-S-E-K-Q-N-E-W-K-K-E-K-L-K-I-L-K-K-V-K-F-Q-N


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-D-I-Y-I-K-S-N-E-K-M-K-V-C-I-N-N-F-Q-I-Q-V-N-N-V-R-T-G-R-A-S-P-E-L-L-N-S-I-Y-V-E-Y-F-G-S-K-V-P-L-R-Q-I-S-N-V-V-V-E-N-Y-H-T-L-K-I-N-I-F-D-D-S-S-T-S-L-I-K-K-A-I-L-N-S-N-L-D-L-N-P-I-L-Y-G-K-D-I-I-V-P-I-P-G-L-T-E-E-R-R-T-H-L-I-K-V-I-R-N-N-A-E-N-A-R-I-Y-I-R-N-I-R-R-D-A-N-D-K-I-K-N-Y-L-K-S-K-I-I-S-E-D-N-E-H-A-A-Q-N-K-I-Q-T-M-T-D-D-Y-I-K-K-I-D-K-I-L-S-E-K-E-K-D-L-M-K-F


### FUNCTION Transcription factor that acts by binding directly to the RNA polymerase  Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters Also required for regulation of fis expression ### SEQUENCE -M-E-K-E-Q-N-K-K-T-S-S-L-N-V-L-A-I-A-G-L-Q-P-Y-Q-K-K-T-D-E-E-Y-M-N-E-K-Q-M-L-H-F-K-K-I-L-E-T-W-K-N-Q-L-T-I-E-I-N-H-T-L-L-Y-I-Q-D-K-S-T-N-F-P-D-P-I-D-R-A-A-Q-E-E-E-F-S-L-E-L-R-N-R-D-R-S-R-K-L-I-K-K-I-Q-E-T-L-K-K-I-K-D-K-D-F-G-Y-C-N-S-C-A-V-E-I-G-I-R-R-L-E-A-R-P-T-A-N-L-C-I-D-C-K-T-L-A-E-I-R-E-K-Q-M-A-G


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-I-V-G-L-S-N-P-K-K-K-Y-H-K-T-R-H-N-V-G-S-W-Y-I-Y-S-L-A-K-N-Y-L-S-I-L-K-E-E-K-K-F-F-G-F-T-G-C-L-N-I-K-S-N-F-I-R-L-L-I-P-D-I-F-M-N-I-N-G-F-S-V-H-R-M-A-S-F-Y-N-I-S-L-N-Q-I-L-I-V-H-D-D-L-D-L-A-P-G-I-I-K-Y-K-Y-S-Y-G-H-S-G-H-N-G-L-R-H-I-I-K-E-F-N-T-K-V-N-F-Y-R-L-R-I-G-I-G-R-P-K-N-K-N-E-I-S-S-F-V-L-S-I-P-D-F-K-E-M-K-L-I-K-K-S-I-S-Y-A-I-K-E-N-F-T-L-L-N-L-I-Q


### FUNCTION Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters ### SEQUENCE -M-N-V-I-E-K-I-E-R-Q-I-K-D-N-I-I-L-I-Y-M-K-G-T-P-Q-S-P-S-C-G-F-S-A-Q-A-V-Q-A-L-S-I-C-G-E-K-F-A-Y-V-D-I-L-E-N-L-D-I-R-K-E-L-P-R-Y-A-N-W-P-T-F-P-Q-L-W-I-K-G-E-L-I-G-G-C-S-I-I-L-E-M-L-E-N-G-E-L-K-K-I-I-S-N-A-V-L-N-S-K


### FUNCTION Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ### SEQUENCE -M-S-N-Q-I-V-L-G-M-L-M-I-F-L-F-S-S-C-S-V-L-E-N-K-H-Y-V-L-N-N-N-L-N-E-S-Y-F-N-L-N-K-F-K-K-N-Y-K-G-M-T-K-E-Q-I-I-Y-I-F-G-N-P-I-I-S-D-S-F-N-D-V-F-H-Y-I-I-C-A-E-E-N-G-F-G-C-H-Q-K-I-L-N-I-F-F-K-K-N-K-V-S-K-L-D-I-R


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-D-N-Q-E-K-K-T-N-Y-Q-N-T-D-K-E-N-D-L-E-K-N-K-E-K-K-N-D-E-S-I-F-Q-N-K-K-M-N-E-I-R-E-K-I-F-K-N-K-K-E-I-N-N-L-K-L-R-H-L-A-N-I-E-N-I-K-K-N-T-E-K-K-I-K-K-I-K-N-A-E-I-E-N-F-F-K-Q-I-I-P-I-I-N-N-L-E-D-I-L-T-I-S-T-K-L-N-L-N-D-E-P-S-I-Q-G-I-E-L-T-L-K-S-L-L-S-I-L-I-K-F-G-V-K-I-E-G-K-K-N-E-I-F-N-P-K-I-H-D-V-I-L-T-E-S-S-N-T-I-E-P-N-Y-I-I-S-V-K-K-K-G-F-I-F-K-K-T-I-L-R-K-A-A-V-V-I-S-K-T


### FUNCTION NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur ### SEQUENCE -M-E-F-V-F-Y-A-C-S-L-I-A-V-I-S-T-L-L-V-I-I-Q-K-N-A-V-Y-S-L-L-Y-L-I-I-S-L-L-S-I-S-G-I-F-F-I-F-G-A-F-F-A-G-A-L-E-V-V-I-Y-A-G-A-I-I-V-L-F-V-F-V-I-M-M-L-N-L-G-K-K-N-D-L-Q-E-K-K-Y-L-N-P-I-F-W-I-G-P-S-F-L-S-L-I-L-F-L-L-M-T-Y-A-I-F-F-V-K-D-K-Q-I-Y-F-S-L-I-D-V-K-E-V-G-I-N-L-F-G-P-Y-L-L-L-V-E-L-S-S-L-L-L-L-S-A-L-V-V-V-F-H-I-G-K-E-K-K


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-D-S-I-I-S-E-E-R-R-K-K-N-A-S-Q-R-S-K-M-R-T-F-I-K-K-V-R-L-A-I-S-S-G-D-K-E-K-S-Y-D-A-F-K-K-M-Q-P-I-I-D-K-Y-A-T-K-G-L-I-H-K-N-K-A-A-R-Y-K-S-I-L-S-F-K-I-A-K-L-H-K-N


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-F-I-V-K-A-E-I-R-D-K-K-G-K-S-F-S-R-K-L-R-I-E-D-K-F-P-G-V-L-Y-G-F-N-N-T-P-I-S-I-T-M-D-H-N-L-V-F-N-L-Q-K-K-E-D-F-Y-K-E-T-L-C-L-L-I-K-E-K-K-Y-T-V-K-V-H-A-I-Q-R-H-A-F-K-M-K-I-L-H-I-D-F-I-Y-A-K-I


### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon  protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-S-F-F-I-K-D-A-N-A-A-V-N-Q-A-L-E-G-N-S-Y-S-L-I-F-M-L-V-T-F-I-L-I-F-Y-F-M-L-F-R-P-Q-Q-K-K-D-K-E-H-K-N-L-M-N-S-I-A-P-G-D-E-V-M-T-T-S-G-F-L-G-R-V-K-K-V-T-E-N-G-Y-V-L-L-Q-L-N-N-T-T-E-I-F-I-K-K-D-F-I-V-S-S-L-P-K-G-T-L-E-S-L


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-V-V-T-K-A-A-I-S-E-N-L-F-E-K-L-K-L-T-K-R-D-S-K-E-F-V-E-F-F-F-E-E-V-R-K-S-L-E-K-G-E-D-V-K-L-S-G-F-G-N-F-Q-L-K-N-K-K-E-R-P-G-R-N-P-R-T-G-E-N-I-L-I-T-Q-R-R-V-V-I-F-K-A-G-Q-K-L-K-N-R-V-E-H-Y-L-M-K-V-K-Y


### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-K-S-Y-F-F-F-I-L-S-N-I-L-I-D-N-F-I-L-V-K-F-L-G-L-C-P-F-I-G-A-S-N-Q-I-K-Q-A-F-G-I-S-F-A-T-S-F-V-V-V-V-S-T-V-L-L-W-F-V-N-F-F-I-L-L-P-F-D-L-V-Y-L-R-I-I-V-Y-M-L-I-I-S-F-G-V-Q-L-I-E-I-I-L-R-G-T-S-P-I-L-Y-R-I-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-A-I-P-L-F-S-L-Y-L-N-H-T-F-L-E-S-I-L-Y-A-V-S-A-S-F-G-F-T-L-V-M-V-I-F-S-S-I-R-E-R-I-L-L-S-D-V-P-L-A-F-Q-G-S-P-I-V-L-I-T-V-S-L-I-S-I-V-F-M-G-F-K-G-L-V-R-I


### FUNCTION Role in flagellar biosynthesis ### SEQUENCE -M-T-P-E-Y-V-M-G-L-F-H-S-A-M-K-V-T-L-M-L-A-S-P-L-L-L-S-A-L-V-S-G-L-I-I-S-I-L-Q-A-A-T-Q-V-N-E-Q-T-L-S-F-I-P-K-I-I-S-I-L-V-V-I-T-L-L-G-P-W-M-L-G-V-M-L-D-Y-M-H-N-L-F-Y-N-I-P-S-I-I-I-R


### FUNCTION FliN is one of three proteins ### SEQUENCE -M-K-K-V-E-K-K-D-N-F-K-K-F-K-N-D-N-I-Y-K-K-D-D-K-N-I-N-Q-E-L-I-N-E-E-K-K-I-K-N-F-N-S-S-N-N-E-S-S-N-E-K-K-I-L-F-D-I-E-M-N-I-T-V-E-L-G-K-S-K-V-K-I-K-D-L-L-N-F-S-K-G-S-M-L-F-L-Q-R-K-K-E-D-P-L-K-V-F-A-N-N-K-L-I-A-L-G-E-I-V-F-S-N-N-K-Y-G-I-R-I-I-S-I-N-N-S-L-N-G-I-N-T-S-V


### FUNCTION Flagellar protein that affects chemotactic events ### SEQUENCE -M-K-Y-K-K-K-I-F-S-I-L-E-N-L-E-K-K-N-I-E-K-D-I-I-N-I-K-N-L-Y-L-Q-K-E-K-Y-V-T-Q-L-S-L-L-K-D-Y-Q-N-E-Y-L-I-K-L-K-S-K-I-E-L-G-I-C-L-Y-Q-W-R-N-Y-N-N-F-I-F-I-L-Y-F-L-I-K-D-N-E-Q-K-I-K-K-N-Q-K-I-L-E-K-S-L-K-Q-Y-S-K-N-Q-I-K-L-K-T-W-N-Y-L-Y-K-K-Y-K-K-K-E-I-K-K-I-L-L-V-E-E-M-I-S-D-E-F-S-Q-L-K-N-L-A-E-G-S-C-Y-N-V


### FUNCTION General  is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-F-Q-K-E-I-K-I-N-A-L-H-G-L-H-T-R-P-A-A-E-F-V-K-E-A-K-N-F-I-S-D-I-H-I-I-Y-H-G-K-S-V-N-A-K-S-L-F-K-I-Q-T-L-G-L-V-K-D-S-V-I-I-L-S-A-E-G-E-D-E-K-K-A-V-E-H-L-S-K-I-M-T-E-L-E


### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-K-I-R-I-P-D-Q-K-K-A-K-N-L-E-K-I-K-W-F-F-I-T-A-I-F-I-T-S-F-F-I-N-N-F-F-D-K-I-G-Y-F-T-R-I-S-I-I-T-L-L-V-V-F-A-I-S-I-A-L-Y-T-K-K-V-K-N-V-F-V-Y-I-N-A-S-K-N-E-M-K-K-I-T-W-P-Q-Y-K-E-T-L-Y-T-T-F-I-I-I-S-V-T-I-L-I-S-L-L-L-W-G-L-D-S-I-I-F-R-L-I-A-F-I-I-S-V-R-F


### FUNCTION Participates in transcription elongation, termination and antitermination In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase , probably by partially suppressing pausing In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho May be required to overcome a kinetic limitation of Rho to function at certain terminators Also involved in ribosomal RNA transcriptional antitermination ### SEQUENCE -M-H-E-S-L-K-K-K-W-Y-V-L-Q-A-F-S-G-F-E-S-R-V-A-Q-S-I-K-E-H-V-K-L-N-K-M-N-D-F-F-G-E-V-M-V-P-S-E-E-V-I-E-I-R-G-G-Q-R-R-K-S-E-Y-K-F-F-P-G-Y-V-L-I-H-M-I-M-T-D-S-T-W-H-L-I-R-N-V-P-R-V-L-G-F-I-G-G-K-S-D-K-P-S-P-I-S-D-K-E-V-D-I-I-I-N-R-L-R-Q-I-G-D-K-P-R-P-K-T-L-F-E-P-G-E-M-I-R-V-N-D-G-P-F-A-D-F-N-G-V-V-E-E-V-D-Y-E-K-S-R-L-K-V-S-V-S-I-F-G-R-A-T-P-V-E-L-D-F-R-Q-V-E-K-N


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-Q-S-Y-I-K-L-Q-V-A-A-G-M-A-N-P-S-P-P-I-G-P-A-L-G-Q-K-G-V-N-I-M-E-F-C-K-L-F-N-K-T-T-E-N-V-E-K-G-L-P-I-P-V-I-V-T-V-Y-S-D-R-S-F-T-F-I-T-K-T-P-P-A-S-V-L-L-K-K-A-A-G-I-K-S-G-S-S-K-P-K-I-E-T-T-G-K-I-T-K-L-Q-I-E-E-I-A-K-T-K-K-N-D-M-T-G-L-N-I-E-S-M-M-R-S-I-E-G-T-A-K-S-M-G-L-I-V-E-D


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-S-K-K-K-T-I-V-S-K-I-N-Q-I-S-N-L-A-L-S-A-I-I-A-N-S-Q-G-I-S-V-N-K-I-N-E-L-R-K-S-G-R-E-I-G-V-K-M-S-I-V-R-N-T-L-L-S-L-A-I-E-N-T-A-F-K-C-L-K-K-K-L-K-G-S-T-F-I-A-Y-S-T-K-H-P-G-S-G-A-R-L-F-K-E-F-E-K-K-N-K-K-F-K-I-T-G-A-V-F-E-G-K-L-L-S-E-L-E-I-N-Q-L-A-D-M-P-T-Y-E-E-A-I-R-K-L-L-L-T-L-K-I-S-I-A-G-K-L-I-Y-T-L-S-A-I-K-E-K-K-E-T-S


### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-Q-L-I-K-I-I-S-K-Q-S-N-L-S-K-I-Q-I-K-S-T-L-E-K-I-L-S-A-I-I-E-S-L-K-K-G-E-S-V-Q-I-V-G-F-G-T-F-K-V-N-S-R-A-S-R-T-G-R-N-P-Q-T-G-K-E-I-I-I-P-A-T-K-V-P-S-F-I-S-G-K-T-L-K-N-A-I-K


### FUNCTION This protein is required for primosome-dependent normal DNA replication ### SEQUENCE -M-K-I-L-V-S-K-K-I-T-L-D-L-F-C-K-N-P-I-Q-I-I-E-K-E-K-N-E-I-I-S-I-S-K-N-K-K-T-V-F-Y-V-I-Q-P-K-A-L-K-K-L-F-D-I-K-E-Y-F-V-K-S-K-I-T-K-K-E-K-K-I-I-E-K-F-P-M-H-T-N-W-I-P-D-K-D-F-I-Q-K-A-A-L-W-G-I-S-L-N-E-E-V-S-K-Y-E-L-A-S-F-I-S-Y-W-E-A-E-G-L-F-F-H-H-I-Q-W-Q-Q-K-L-A-R-S-L-E-R-S-R-S-M-N-N-A-I-Q-Q-K-K-D-I-T-Y-I-P-V-P-D-Q-K-T-P-D-G-F-R-G-K


### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-R-V-Y-H-S-N-N-F-R-S-G-R-K-I-I-F-E-K-E-P-C-L-I-E-S-S-E-F-V-K-P-G-K-G-Q-S-F-V-R-V-K-L-R-K-L-L-T-K-Q-L-I-E-K-T-F-K-S-T-D-S-L-E-I-A-D-V-S-E-Y-T-L-S-Y-L-Y-N-D-G-H-F-W-Y-F-I-N-N-N-F-E-E-L-S-V-D-K-K-I-V-G-V-N-K-K-W-L-S-E-Q-D-T-C-V-I-T-F-W-N-N-Q-A-I-S-I-T-P-N-I-F-V-E-L-K-V-I-D-T-E-I-A-L-K-S-D-T-I-N-T-T-T-K-L-A-T-L-S-T-G-A-I-L-K-V-P-L-F-I-Q-I-G-S-L-I-K-V-D-T-R-S-G-E-Y-V-S-R-I-K


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-S-S-D-K-A-F-T-L-D-I-V-T-P-Q-K-L-F-F-S-G-E-I-N-S-V-I-A-P-G-L-N-G-L-F-Q-V-L-K-G-H-A-P-L-L-A-A-L-K-S-G-K-V-R-L-S-L-S-D-R-S-E-D-T-F-Q-I-A-G-G-F-F-E-V-S-G-N-K-A-I-L-L-T-E-E-V-S


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-P-A-S-S-K-S-R-T-S-A-V-P-T-I-E-E-L-I-Q-R-L-E-E-I-T-R-N-I-E-N-P-D-T-G-L-E-N-S-I-A-L-Y-E-E-G-M-S-L-A-E-E-C-R-K-R-L-L-E-T-R-K-K-L-E-T-I-N-P-A-E-T-A-R-P-A-K-P-E-N-A-P-E-S-P-R-M-N-D-L-F-G-T-E-S


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-Q-Q-L-I-R-H-G-R-S-M-K-A-S-K-T-A-S-P-A-L-E-K-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-S-N-K-I-E-V-T-A-Y-I-P-G-E-G-H-N-L-Q-E-H-S-I-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-S-L-D-T-S-G-V-A-D-R-K-Q-S-R-S-K-Y-G-A-K-V-P-K-A-G-A-A-P-A-K-K-K


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-V-Q-Q-K-I-R-I-K-L-K-S-Y-D-H-S-L-V-D-K-W-A-L-K-I-I-D-V-V-K-Q-T-E-A-I-I-F-G-P-I-P-L-P-T-K-T-H-V-Y-T-V-N-R-S-P-H-V-D-K-K-S-R-E-Q-F-A-F-S-S-H-K-R-L-I-E-I-I-N-P-T-A-R-T-I-D-M-L-M-K-L-E-L-P-S-G-V-D-V-E-I-K-S


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-K-N-P-L-L-R-P-W-L-T-E-K-S-T-K-L-T-E-Q-K-G-Q-Y-V-F-Q-V-K-I-D-A-D-K-F-D-I-K-K-A-V-E-E-K-F-G-V-D-V-V-S-I-R-T-I-N-C-L-G-K-S-K-R-Q-Y-T-R-K-G-L-I-A-G-K-K-S-D-W-K-K-A-I-V-T-L-G-D-G-Q-T-I-D-Y-Y-A-K-P-A-E-K-S-E-K


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-E-F-K-L-E-K-R-I-L-D-M-N-S-K-G-E-K-K-V-V-K-T-W-S-R-S-S-M-I-S-P-D-F-V-G-H-T-V-A-V-H-N-G-K-T-H-V-P-V-Y-V-T-E-N-M-V-G-H-K-L-G-E-F-A-P-T-R-L-F-R-G-H-A-G-G-K-A-E-K-G-G-S-A-P-R-K-K


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-Q-A-K-A-I-L-R-H-T-P-T-S-P-R-K-M-R-L-V-A-G-L-V-R-G-K-R-V-D-Q-A-K-A-I-L-H-N-S-T-K-S-A-S-R-N-V-M-V-T-L-K-S-A-V-A-N-W-S-Q-L-N-P-D-E-R-L-N-D-N-E-L-F-V-K-A-I-F-V-D-E-G-P-S-L-K-R-L-L-P-A-P-M-G-R-A-Y-R-I-R-K-R-S-N-H-L-T-I-V-V-D-K-V-E-N-K-V-T-K


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-Q-Y-R-K-T-Q-R-G-R-M-K-G-N-A-Q-R-G-T-A-V-T-F-G-S-F-G-L-K-A-M-E-P-A-W-I-T-S-R-Q-I-E-A-A-R-I-A-M-N-R-Y-M-K-R-D-G-K-I-W-I-R-I-F-P-D-K-P-V-S-K-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-F-W-V-A-V-V-K-P-G-R-V-M-F-E-A-D-G-V-P-R-E-V-A-V-E-A-F-R-L-A-A-K-K-L-P-I-K-T-K-F-I-V-R-P-D-Y-E-G


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-S-G-A-E-T-R-G-R-K-K-S-W-L-G-K-V-V-S-D-S-M-D-K-G-I-V-V-A-V-E-R-R-V-Q-H-P-V-Y-K-K-Y-F-K-K-T-T-R-L-M-A-H-D-E-N-N-E-A-G-V-G-D-L-V-R-I-T-E-C-R-P-L-S-K-N-K-S-C-R-L-V-E-I-V-E-K-A-K


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-K-E-T-N-L-V-V-A-D-N-S-G-A-K-K-V-R-C-I-H-V-F-G-G-T-G-R-R-Y-A-A-L-G-D-Q-I-M-V-S-V-K-A-A-V-P-G-G-V-V-K-K-K-D-V-C-K-A-V-V-V-R-C-V-K-E-Q-K-R-K-D-G-S-Y-I-R-F-D-E-N-A-V-V-L-L-N-A-Q-G-E-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-K-R-Y-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-T-G-I-K-K-V-K-L-H-V-R-K-N-D-E-V-T-V-I-A-G-N-D-K-G-K-S-G-K-V-L-K-V-F-P-Q-K-G-R-V-I-V-E-G-V-N-I-R-K-R-H-M-R-P-T-Q-G-M-P-Q-G-A-I-I-E-R-E-F-P-I-H-V-S-N-V-K-K-S


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-P-A-R-L-E-V-Y-Y-R-E-T-V-V-P-K-L-M-E-R-F-K-Y-K-S-I-M-M-V-P-R-L-E-K-I-S-V-N-I-G-V-G-E-A-A-Q-E-P-K-L-L-E-T-A-M-Q-E-L-G-Q-I-T-G-Q-K-P-Q-V-R-K-A-K-K-A-I-S-N-F-K-L-R-E-G-Q-A-I-G-C-R-V-T-L-R-R-K-I-M-F-E-F-M-D-R-F-I-S-V-A-V-P-R-I-R-D-F-R-G-L-S-D-T-S-F-D-G-R-G-N-Y-N-V-G-I-R-E-Q-I-I-F-P-E-I-D-I-D-K-V-P-R-I-N-G-M-D-I-S-F-V-T-S-A-K-T-D-E-E-A-Y-E-L-L-S-L-L-G-M-P-F-K-K-K-N-Q


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-R-K-S-I-I-A-R-N-E-K-R-K-K-L-V-E-K-Y-A-A-K-R-E-E-L-K-A-A-G-D-Y-Q-A-L-S-Q-L-P-R-D-S-S-A-T-R-L-R-T-R-C-V-L-T-G-R-G-R-G-N-Y-R-K-F-G-L-C-R-N-M-F-R-K-L-A-L-E-G-K-L-P-G-V-R-K-A-S-W


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-M-P-I-R-L-A-D-Q-A-Q-V-E-V-K-E-N-M-I-N-V-T-G-P-K-G-A-L-S-Q-A-L-V-D-E-V-I-V-S-V-A-D-G-A-V-T-V-Q-R-K-D-D-S-K-R-A-R-A-M-H-G-L-Y-R-M-L-V-S-N-M-V-E-G-V-T-K-G-F-T-R-K-L-E-M-S-G-V-G-Y-R-A-E-L-K-G-N-L-L-A-L-T-L-G-Y-S-H-M-I-Y-F-Q-P-P-A-E-I-K-I-E-V-P-D-P-T-T-V-L-V-S-G-I-D-K-A-L-V-G-Q-I-A-A-K-I-R-S-F-R-K-P-E-P-Y-R-G-K-G-I-K-Y-E-G-E-V-I-R-R-K-E-G-K-A-A-G-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-Q-V-D-K-T-A-R-R-Q-K-I-K-A-R-S-R-A-V-V-R-G-T-Q-E-R-P-R-L-C-V-F-R-S-L-S-Q-I-Y-A-Q-L-I-D-D-E-S-G-K-T-L-M-A-A-S-S-M-S-K-E-N-A-G-L-T-G-T-K-S-E-V-S-A-A-I-G-K-Q-I-A-E-K-A-L-A-Q-G-I-S-R-V-V-F-D-R-N-G-F-R-Y-H-G-R-I-K-A-L-A-D-G-A-R-E-A-G-L-I-F


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-K-K-S-G-R-N-I-K-P-G-E-L-N-L-K-E-K-L-V-H-I-N-R-T-A-K-V-V-K-G-G-K-R-F-G-F-N-A-I-V-V-V-G-D-K-E-G-H-V-G-Y-G-L-G-K-A-N-E-V-Q-D-A-I-A-K-G-V-E-D-G-K-K-N-V-I-K-V-P-I-V-K-G-T-I-P-H-P-I-V-A-K-Y-G-S-A-K-V-L-M-K-P-A-T-P-G-T-G-L-I-A-G-G-A-V-R-A-V-L-E-M-A-G-I-H-D-I-L-T-K-S-L-G-S-S-N-P-H-N-V-V-K-A-A-I-K-G-L-Q-N-I-S-D-A-N-D-V-A-E-R-R-S-K-S-L-K-E-V-F-E-S


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-D-L-S-S-L-R-P-A-K-G-A-V-K-A-R-K-R-V-G-R-G-P-G-S-G-N-G-T-T-A-G-K-G-N-K-G-Q-Q-S-R-S-G-Y-Q-R-P-V-I-E-G-G-Q-M-P-I-Y-R-R-L-P-K-F-G-F-T-P-P-N-Q-K-A-V-A-C-V-N-V-A-Q-I-Q-M-W-I-E-K-G-L-V-G-E-E-I-S-V-L-D-L-K-H-L-C-N-A-S-N-Q-E-Y-F-K-V-L-G-N-G-E-L-T-S-T-V-T-I-T-A-H-F-F-S-K-S-A-E-E-K-I-A-K-A-G-G-K-I-V-K-A-Y-R-T-L-E-E-A-A-K-V-N-G-L-P-F-E-E-A-L-L-T-P-K-A-K-V-V-K-V-K-K-E-K-K-S-V-K-S


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-S-I-E-V-E-G-E-I-L-E-A-L-P-N-A-Q-F-R-V-K-L-E-N-G-L-E-V-L-A-H-V-S-G-K-I-R-M-H-Y-I-R-I-L-P-G-D-K-V-K-V-Q-I-S-P-Y-D-L-S-K-G-R-I-T-Y-R-Y-K


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-R-L-A-G-V-N-L-P-L-N-K-H-A-V-I-A-L-T-Y-V-Y-G-I-G-N-T-S-A-K-N-I-L-A-K-A-G-V-A-P-D-K-K-I-S-E-L-S-D-E-E-A-H-A-I-R-E-I-I-G-N-E-Y-T-V-E-G-E-A-R-A-E-Q-Q-L-S-I-K-R-L-M-D-I-G-C-Y-R-G-L-R-H-R-R-S-L-P-V-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-K-R-K-T-V-A-G-K-K-K-A-G-K-K


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-T-A-S-R-K-K-K-K-V-K-V-T-P-E-G-T-V-H-I-K-A-S-F-N-N-V-M-V-T-I-T-D-T-L-G-N-T-V-S-W-S-S-A-G-K-N-G-F-K-G-S-K-K-N-T-P-Y-A-S-Q-V-T-S-E-A-A-A-K-E-A-Y-D-L-G-M-R-Y-V-D-V-L-I-K-G-P-G-S-G-R-D-A-A-I-R-A-L-Q-G-V-G-L-E-V-R-S-I-R-D-I-T-P-L-P-H-N-G-C-R-P-P-K-R-R-R-V


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-N-I-T-T-A-D-F-F-C-S-Y-S-S-L-N-G-L-P-S-D-G-R-P-E-I-V-F-V-G-R-S-N-V-G-K-S-S-L-L-N-S-L-C-A-R-K-G-L-A-K-T-S-S-T-P-G-K-T-R-L-I-N-Y-F-I-I-N-D-N-L-Y-F-V-D-L-P-G-Y-G-Y-A-K-V-G-Q-G-E-R-E-S-W-G-K-L-L-T-G-Y-I-Q-K-R-G-E-I-A-L-V-V-L-L-V-D-S-R-H-P-G-M-A-S-D-L-E-M-M-E-F-L-D-Y-C-G-R-P-F-G-I-V-L-T-K-W-D-K-L-K-Q-A-E-K-S-K-A-S-R-T-I-E-S-C-A-P-N-A-R-F-I-V-N-Y-S-S-L-S-G-S-G-R-D-R-L-L-A-S-I-D-T-F-T-Q


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-N-T-L-K-Q-Y-E-C-T-V-I-I-D-G-G-L-Q-D-D-A-I-A-A-V-M-E-L-V-K-K-T-V-T-D-K-G-G-V-I-N-N-V-L-E-V-G-R-R-K-M-A-Y-L-I-R-K-T-S-I-G-Y-Y-A-H-I-E-F-D-A-V-P-S-V-I-A-E-I-E-R-V-F-R-Y-E-E-A-I-L-R-F-L-I-I-Q-L-S-S-P-L-L-E-M-R-K-R-V-E-K-Y-S-V-M-L-G-S-P-E-D-Q-A-E-A-E-A-D-A-D-A-K-N


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-N-A-L-A-S-K-K-K-V-S-K-N-Q-V-V-F-F-D-Y-R-D-E-R-K-L-K-R-F-I-N-D-Q-G-K-I-I-P-R-R-I-T-G-L-S-A-K-E-Q-S-L-L-T-H-S-I-K-W-A-R-F-L-A-I-I-P-Y-V-A-D-E-Y-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-I-I-L-R-K-D-V-A-T-L-G-D-A-G-E-V-V-T-V-K-N-G-Y-A-N-N-Y-L-I-P-Q-G-Y-A-I-R-A-T-E-G-T-L-K-A-L-E-T-E-K-K-Q-Q-A-R-K-I-E-L-Q-R-T-N-A-R-E-L-A-A-K-I-E-Q-M-T-L-K-V-L-A-K-A-G-E-S-G-K-L-F-G-T-V-T-A-G-D-I-A-E-A-L-K-A-Q-G-V-D-I-D-R-R-K-I-H-L-E-A-P-I-K-A-L-G-K-Y-E-A-D-A-K-L-F-M-D-I-T-A-K-L-S-I-E-V-E-A-E-G-A-S-E-E


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-K-S-T-N-S-V-A-S-K-A-R-R-K-R-I-L-K-K-A-K-G-Y-W-G-S-R-G-N-V-L-T-V-V-K-H-A-V-D-K-A-E-Q-Y-A-Y-R-D-R-R-V-K-K-R-N-F-R-S-L-W-I-M-R-I-N-A-A-A-R-Q-N-G-V-S-Y-S-R-L-M-D-A-I-H-K-K-N-I-E-I-D-R-K-A-L-A-E-I-A-V-K-D-P-A-A-F-S-L-I-V-K-T-A-L-D


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-A-A-E-I-K-D-K-V-Y-D-I-I-V-S-K-M-G-V-N-K-D-Q-I-K-P-E-S-K-F-A-D-D-L-G-A-D-S-L-D-T-V-E-L-I-M-E-L-E-N-E-F-G-V-Q-I-P-D-E-D-A-E-K-I-G-T-V-Q-Q-A-I-D-Y-I-V-N-K-K-V-S


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-V-M-K-N-V-L-L-V-G-A-G-G-F-A-G-S-V-A-R-Y-L-V-A-L-A-V-P-F-S-G-T-G-F-P-F-A-T-F-A-V-N-L-L-G-S-F-L-I-G-F-I-S-E-L-A-L-S-T-T-L-L-S-P-E-A-R-L-L-L-T-T-G-F-C-G-G-F-T-T-F-S-T-A-M-Y-E-T-G-G-L-M-R-D-G-E-A-L-Y-A-S-L-Y-V-A-G-S-L-A-G-G-L-A-C-L-F-S-G-T-L-L-A-K-L-W-Q


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-Q-V-Q-N-I-E-G-S-L-N-A-S-G-L-K-F-A-L-V-V-S-R-F-N-D-F-I-G-Q-K-L-V-E-G-A-I-D-C-I-V-R-H-G-G-S-A-D-E-I-T-V-I-R-C-P-G-A-F-E-L-P-S-V-T-R-K-A-M-L-S-G-K-Y-D-A-I-V-T-L-G-V-I-I-R-G-S-T-P-H-F-D-V-I-A-A-E-A-T-K-G-I-A-Q-V-G-M-E-A-A-I-P-V-S-F-G-V-L-T-T-E-N-L-E-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-F-D-A-A-L-A-A-I-E-M-A-N-L-Y-K-Q-L


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-E-I-G-V-D-I-V-E-I-A-R-I-R-S-S-Y-D-R-F-G-E-A-F-M-K-K-I-L-T-S-A-E-M-A-Q-C-L-S-K-P-D-P-V-A-S-L-A-G-R-F-A-A-K-E-A-V-S-K-A-L-G-T-G-I-A-K-G-L-T-W-H-S-I-E-V-L-N-D-E-T-G-K-P-C-V-S-V-Y-A-P-S-F-S-G-R-V-S-I-S-I-S-H-D-R-Y-S-A-V-A-M-A-L-F-E-P-R


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-V-T-T-K-D-V-A-Y-I-A-E-L-A-R-L-K-F-T-D-A-E-Q-E-K-M-A-S-E-L-N-M-I-L-H-Y-I-E-K-L-N-G-I-D-T-E-G-V-E-P-L-S-T-I-H-D-Q-I-N-V-L-R-A-D-V-E-H-T-P-L-S-N-D-E-A-L-K-N-A-P-D-S-Q-D-R-F-F-K-V-P-K-V-I-G


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-M-S-I-A-M-S-V-V-E-A-V-V-D-K-A-R-E-E-G-G-G-K-I-T-G-I-D-L-V-V-G-R-L-A-G-V-E-V-E-S-L-K-F-C-F-G-A-A-A-R-G-T-L-A-E-G-A-E-L-V-I-E-E-P-E-G-R-G-R-C-E-A-C-G-A-E-F-P-V-T-S-F-Y-A-K-C-S-A-C-G-Q-F-R-V-K-I-E-S-G-R-E-L-A-V-R-S-F-T-I-E


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-S-K-T-L-S-F-K-T-Y-S-A-K-P-G-E-V-K-R-T-W-H-I-I-D-A-E-N-Q-V-L-G-R-M-A-A-Q-I-A-N-V-L-R-G-K-H-K-P-Q-F-T-P-H-I-D-T-G-D-F-V-V-V-T-N-A-A-K-V-A-L-S-G-K-K-R-D-D-K-T-Y-F-S-H-S-H-Y-P-G-G-V-R-I-D-S-V-K-D-L-L-Q-K-K-P-E-K-V-I-E-H-A-V-W-G-M-L-P-H-N-N-L-G-R-Q-L-F-K-K-L-K-V-Y-A-G-P-E-H-P-H-A-A-Q-M-P-V-E-M-K-I-N-Q


### FUNCTION Modulates RecA activity ### SEQUENCE -M-D-E-G-K-K-S-S-A-L-D-H-A-L-R-L-L-A-G-R-A-H-G-R-A-E-L-E-S-K-L-K-K-K-G-F-D-S-E-S-I-A-K-A-L-A-R-L-D-E-L-N-L-T-D-D-R-A-F-A-Q-S-C-T-A-S-M-A-R-R-K-P-E-G-R-L-K-T-R-A-R-L-K-Q-K-G-L-P-D-N-I-I-D-E-A-L-N-G-C-D-Q-T-E-L-C-R-S-A-A-E-K-K-L-R-T-L-P-A-S-P-D-Q-K-K-K-K-L-I-T-F-L-K-N-R-G-F-D-W-E-T-I-R-E-T-V-K-L-V-L-G-E-E-S-A-R-S-D-Q-L-D


### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-S-L-K-I-T-E-E-C-T-F-C-A-A-C-E-P-E-C-P-V-N-A-I-S-A-G-S-D-I-Y-V-I-D-E-S-A-C-T-E-C-E-G-Y-A-D-S-P-A-C-V-A-V-C-P-A-E-C-I-V-K-A


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-K-T-Y-R-R-Q-L-R-E-K-I-I-Q-A-L-Y-T-L-E-L-R-D-V-D-T-D-S-A-A-N-W-L-L-T-K-E-I-M-D-D-P-N-A-M-K-F-F-N-H-L-M-Q-S-I-V-R-N-R-E-E-I-D-R-Y-I-A-K-H-T-F-N-W-D-M-S-R-I-A-I-I-D-K-N-I-L-R-M-A-L-A-E-I-L-Y-C-E-D-I-P-P-K-V-S-I-N-E-A-I-E-I-A-K-K-F-S-S-T-D-K-S-S-K-F-V-N-G-I-L-D-A-I-F-N-D-M-K-A-E-G-R-I-K-K-C-G-R-G-L-V-D-H-S-E-Q-K-M-Q-K-T-E-N-N-R


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-N-I-P-D-N-L-R-Y-T-K-D-H-E-W-I-K-L-L-E-D-G-L-T-A-L-V-G-I-T-D-F-A-Q-S-E-L-G-D-I-V-F-V-E-T-K-P-V-G-T-K-V-A-A-H-G-T-F-G-T-V-E-A-V-K-T-V-A-D-L-F-A-P-A-A-G-E-I-V-E-V-N-A-G-L-D-D-A-A-I-V-N-S-D-P-Y-N-E-G-W-I-V-K-M-K-L-D-N-P-A-D-V-E-A-L-L-S-P-A-D-Y-S-A-L-I-G-E


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-F-G-L-G-G-Q-E-L-V-L-I-L-L-I-V-L-L-L-F-G-A-Q-K-L-P-E-L-A-K-G-L-G-K-G-I-K-E-F-K-K-A-Q-N-E-I-E-E-E-F-N-K-A-T-D-D-S-S-S-K-E-K-K-E-T-K-A