### FUNCTION Specifically inhibits an endogenous intracellular serine proteinase ### SEQUENCE -S-A-G-K-F-I-V-I-F-K-N-D-V-S-E-D-K-I-R-E-T-K-D-E-V-I-A-E-G-G-T-I-T-N-E-Y-N-M-P-G-M-K-G-F-A-G-E-L-T-P-Q-S-L-T-K-F-Q-G-L-Q-G-D-L-I-D-S-I-E-E-D-G-I-V-T-T-Q


### FUNCTION Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly ### SEQUENCE -M-S-N-T-A-P-G-P-T-V-A-N-K-R-D-E-K-H-R-H-V-V-N-V-V-L-E-L-P-T-E-I-S-E-A-T-H-P-V-L-A-T-M-L-S-K-Y-T-R-M-S-S-L-F-N-D-K-C-A-F-K-L-D-L-L-R-M-V-A-V-S-R-T-R-R


### FUNCTION Required for efficient viral DNA synthesis and the late accumulation of viral IE transcripts ### SEQUENCE -M-G-G-S-P-V-P-Q-L-T-T-V-T-Q-G-L-M-P-S-V-R-M-D-F-R-A-R-R-P-L-R-R-L-A-F-Y-A-P-R-A-R-R-R-L-F-Q-N-H-I-H-P-E-Q-R-R-V-L-V-G-E-G-D-E-E-M-L-P-D-L-P-M-E-I-D-I-V-I-D-R-P-P-Q-Q-P-L-P-N-P-L-V-L-L-L-D-D-V-P-P-H-V-P-G-F-A-P-Y-R-V-P-R-P-H-P-M-I-P-E-E-H-W-D-Q-F


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-V-K-L-A-F-P-R-E-L-R-L-L-T-P-K-H-F-T-Y-V-F-Q-Q-P-Q-R-A-S-S-P-E-I-T-I-L-G-R-P-N-E-L-G-H-P-R-I-G-L-T-I-A-K-K-N-V-K-R-A-H-E-R-N-R-I-K-R-L-A-R-E-S-F-R-L-N-Q-H-E-L-P-P-M-D-F-V-V-L-V-R-K-G-V-A-E-L-D-N-R-A-L-T-E-A-L-G-K-L-W-R-R-H-C-R-L-A-R-A-S


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-N-D-K-L-I-V-E-R-Q-E-V-E-N-K-S-E-G-G-I-V-L-T-S-Q-S-V-K-K-S-N-R-G-K-V-I-A-A-G-L-G-K-R-L-E-N-G-E-R-A-S-M-E-V-K-V-G-D-V-V-I-F-N-D-G-Y-G-V-K-T-E-K-M-D-G-K-E-Y-L-I-L-S-E-S-D-V-L-A-I-V-E


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-E-R-Q-E-V-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-E-K-S-T-R-G-V-V-L-A-V-G-K-G-R-I-L-E-N-G-T-V-Q-P-L-D-V-K-V-G-D-T-V-I-F-A-E-S-Y-G-T-K-T-E-K-I-D-G-K-E-V-L-I-M-S-E-N-D-I-M-A-I-V-D


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-L-P-I-I-T-Y-P-H-P-L-L-K-K-R-S-E-P-V-T-L-F-D-E-E-L-R-Q-F-L-D-E-M-Y-I-T-M-L-A-K-N-G-V-G-L-A-A-V-Q-V-G-N-P-I-R-A-L-I-V-N-I-P-D-E-E-G-N-Q-E-R-E-N-L-L-E-I-I-N-P-E-F-L-S-K-E-G-E-I-Q-F-N-E-G-C-L-S-V-P-E-F-Y-E-D-V-T-R-F-D-R-V-R-L-T-Y-Q-D-R-Y-G-E-R-H-E-I-E-A-E-G-Y-L-A-V-A-L-Q-H-E-I-D-H-L-N-G-I-L-F-I-D-K-L-S-L-I-K-R-K-K-F-E-K-E-L-K-K-R-Q-R-A-S-L


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-Y-I-P-Y-V-I-E-K-T-G-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-S-G-E-I-N-D-G-V-A-S-S-I-V-S-Q-M-L-F-L-E-A-E-D-P-E-K-D-I-Y-L-Y-I-N-S-P-G-G-V-I-T-S-G-M-S-I-Y-D-T-M-N-Y-V-K-P-D-I-C-T-I-C-I-G-Q-A-A-S-M-G-A-F-L-L-S-C-G-T-K-G-K-R-F-S-L-P-N-S-R-I-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-T-D-I-E-I-Q-A-K-E-I-L-R-L-K-S-I-L-N-G-I-L-A-S-N-T-G-Q-P-L-E-K-I-A-K-D-T-D-R-D-F-F-M-S-A-Q-E-S-K-E-Y-G-L-I-D-N-V-L-E-K-S-F-K


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-N-M-T-K-M-A-K-A-N-E-I-K-R-E-W-V-V-L-D-A-E-G-K-T-F-G-R-L-M-T-Q-V-A-T-L-L-R-G-K-H-R-P-D-Y-T-P-H-V-D-C-G-D-F-V-V-I-V-N-A-S-K-V-V-F-S-G-L-K-L-E-A-K-E-Y-F-T-H-S-G-Y-F-G-S-T-K-S-Q-T-L-Q-E-L-L-E-K-N-P-E-K-L-F-R-L-A-A-R-G-M-L-P-K-T-K-L-G-R-A-M-L-K-K-L-K-V-Y-A-G-A-E-H-P-H-T-A-Q-V-T-K


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-L-E-G-I-I-R-E-S-I-S-K-S-A-V-K-A-L-R-N-D-G-Y-L-I-A-N-I-Y-G-K-G-Q-E-N-T-H-C-A-F-K-K-N-D-F-I-R-A-V-K-S-K-T-N-I-I-F-P-V-K-V-G-G-K-E-I-N-V-V-V-Q-E-Y-Q-K-D-P-I-T-S-D-L-L-H-V-D-L-M-L-V-Q-P-G-V-E-T-K-F-L-V-P-V-K-T-A-G-S-A-K-G-L-K-N-K-G-V-L-I-L-S-K-K-R-V-K-V-K-C-S-P-E-N-L-P-A-S-Y-E-L-D-V-S-D-L-D-V-G-D-A-I-L-V-R-D-L-P-E-L-P-N-V-K-V-I-E-K-E-S-V-A-I-V-G-V-I-K-A-K


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-L-V-V-G-L-G-N-P-G-K-T-Y-E-S-T-R-H-N-I-G-F-R-V-I-D-A-L-L-E-R-R-S-A-L-N-A-T-K-S-T-F-K-G-E-L-H-K-E-G-E-N-L-F-L-K-P-T-T-Y-M-N-L-S-G-E-S-A-L-P-V-S-T-F-Y-K-P-E-K-I-L-V-I-H-D-D-L-D-L-P-F-G-A-I-R-L-K-R-G-G-G-N-G-G-H-N-G-L-K-S-L-D-K-L-L-G-N-D-Y-Y-R-L-R-I-G-I-G-K-P-P-L-G-W-E-V-A-D-Y-V-L-A-R-F-S-Q-E-E-E-Q-E-L-E-E-R-L-F-P-H-A-K-E-A-I-E-S-F-L-E-G-K-M-E-W-D-R-L-V-S-R-Y-S-L-K-P-S-T-P-K-E-K-V


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-I-T-V-V-E-S-S-F-L-T-S-A-S-A-L-S-Q-T-P-P-P-K-N-S-E-V-V-F-I-G-R-S-N-V-G-K-S-T-L-I-N-L-I-V-D-S-K-G-L-A-K-S-S-S-T-P-G-K-T-Q-L-I-N-Y-F-E-T-I-W-K-R-G-E-E-R-I-P-L-W-L-V-D-L-P-G-F-G-Y-A-K-V-S-K-E-M-R-K-D-W-G-E-K-L-I-H-F-L-Q-E-R-R-S-I-K-L-F-V-Q-L-I-D-A-R-H-P-D-L-A-I-D-A-E-A-W-A-M-I-G-A-I-K-R-G-D-Q-K-V-I-R-V-F-T-K-M-D-K-L-N-R-N-D-Q-K-K-L-Q-Q-R-Y-P-D-A-C-F-T-A-M-L-G-K-E-G-I-A-S-V-R-E-R-V-L-K-D-V-L-G-E-E-A


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-G-I-D-L-V-S-I-E-R-I-E-A-F-I-A-K-H-G-Q-R-G-L-E-R-F-L-L-P-E-E-I-L-L-A-N-K-P-E-T-I-A-G-F-W-A-A-K-E-A-C-S-K-A-L-G-T-G-I-G-A-E-V-G-F-H-D-I-R-L-F-K-N-P-K-G-A-P-L-L-E-L-S-P-R-V-K-D-R-F-E-I-D-S-C-A-L-S-I-T-H-D-K-G-F-A-I-A-V-V-A-M-E-K-R-R-A


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-N-I-Q-Q-G-K-V-W-K-F-G-E-N-I-D-T-D-L-I-I-A-A-R-Y-L-N-T-S-D-P-Q-V-L-A-S-H-V-M-E-D-A-R-P-D-F-L-Q-H-F-T-K-G-D-F-I-V-A-G-E-N-F-G-C-G-S-S-R-E-H-A-P-V-A-L-K-T-A-G-V-S-A-V-I-A-K-S-F-A-R-I-F-Y-R-N-S-F-N-T-G-L-P-I-L-E-V-K-E-T-D-E-I-R-E-G-D-T-L-E-V-D-M-A-Q-G-T-I-K-N-L-T-R-N-Q-T-Y-A-F-K-P-I-P-P-F-M-M-E-L-L-E-S-G-G-L-I-E-H-A-K-A-K-I-A-Q-G-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-E-F-L-V-E-K-I-G-M-S-R-T-I-S-V-P-S-T-P-V-T-L-L-K-V-K-D-A-K-V-C-E-V-L-G-N-G-K-A-L-V-A-Y-A-Q-G-K-D-A-N-K-A-I-E-G-Q-Q-K-K-Y-N-L-S-K-E-F-N-R-F-A-T-L-E-V-A-N-G-E-A-G-D-Q-D-V-A-P-L-A-Q-A-V-R-V-K-V-S-L-Q-T-K-G-R-G-F-T-G-V-M-K-R-W-N-F-A-G-G-P-A-A-H-G-H-R-F-K-R-R-T-G-S-I-G-N-R-E-W-P-G-R-V-Q-P-G-K-K-M-A-G-Q-Y-G-N-E-K-V-T-V-Q-N-E-I-V-S-F-D-A-E-N-K-I-L-V-L-K-G-S-I-P-G-F-N-G-A-F-G-R-I-K-V-V-K


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-A-D-I-T-D-I-K-S-I-M-Y-T-E-K-S-L-Q-I-Q-E-S-G-V-L-V-V-Q-T-S-P-K-V-S-K-N-Q-L-K-E-V-F-K-E-Y-F-G-F-T-P-V-R-V-N-S-L-R-Q-A-G-K-I-K-R-F-R-G-V-E-G-K-R-A-S-F-K-K-F-Y-V-K-L-P-E-G-A-K-I-E-S-L-A-V


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-I-K-K-G-P-F-I-D-D-H-L-M-K-K-V-L-K-S-K-E-T-K-D-N-K-P-I-K-T-W-S-R-R-S-T-I-V-P-D-M-I-G-L-T-L-N-V-H-N-G-R-A-F-V-P-V-Y-V-T-E-N-H-V-G-Y-K-L-G-E-F-A-P-T-R-T-F-K-G-H-K-G-S-V-Q-K-K-I-G-K


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-K-A-L-L-R-Y-I-R-L-S-P-T-K-A-R-L-V-A-R-E-V-Q-G-M-N-A-E-L-A-I-A-S-L-E-F-M-P-N-K-A-A-K-V-I-S-K-V-I-A-S-A-V-A-N-G-G-M-G-A-E-N-A-V-V-K-S-C-R-V-D-A-G-P-V-L-R-R-F-T-P-R-A-R-G-R-A-T-P-I-R-K-P-T-S-H-V-F-V-E-V-V-E-Q-S-K-D-K


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-F-R-K-Q-M-K-G-R-N-R-G-K-S-F-R-G-N-S-L-A-F-G-D-I-G-I-K-A-T-E-H-G-R-I-D-S-R-Q-I-E-A-A-R-I-A-M-T-R-H-I-K-R-A-G-K-I-W-I-R-V-F-P-D-K-P-L-T-A-K-P-L-E-T-R-M-G-K-G-K-G-S-V-D-K-W-V-M-N-I-Q-P-G-R-I-V-Y-E-M-A-G-I-E-E-E-L-A-R-E-A-L-A-L-A-Q-S-K-L-P-F-K-T-K-I-V-T-S-E-S-E-N-E-I-Y


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-N-E-Q-A-H-K-R-V-I-Q-G-K-V-V-T-K-A-G-D-K-S-V-T-I-L-V-E-R-R-V-T-H-P-K-Y-R-K-I-V-K-R-F-K-K-Y-I-V-H-D-E-S-N-A-V-K-V-G-D-M-I-E-A-I-E-C-R-P-L-S-K-R-K-S-F-S-L-H-K-V-L-S-V-G-V-E-A


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-S-F-T-R-L-T-V-A-D-N-S-G-A-K-E-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-T-V-G-D-V-I-I-A-S-V-K-K-A-L-P-N-G-K-I-K-K-G-Q-V-V-K-A-V-V-V-R-T-K-K-E-V-Q-R-D-N-G-S-L-I-R-F-D-D-N-A-A-V-I-L-D-N-K-R-E-P-V-G-T-R-I-F-G-P-V-G-R-E-V-R-Y-A-N-F-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-V-K-F-Q-I-K-K-G-D-K-V-Q-V-I-A-G-D-D-K-G-K-V-A-E-V-I-K-V-M-P-K-S-S-Q-V-I-V-A-G-C-K-V-A-K-K-S-V-K-P-S-E-Q-N-P-K-G-G-F-V-N-K-E-M-P-I-H-I-S-N-V-K-K-V-E-A


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-Y-Q-L-K-K-L-Y-N-E-E-L-K-A-K-L-S-E-E-L-G-I-K-N-P-M-L-L-P-K-L-E-K-I-V-I-S-V-G-A-G-D-H-A-K-D-T-K-V-M-Q-N-I-A-D-T-I-S-L-I-A-G-Q-K-A-V-I-T-I-A-K-K-S-V-A-G-F-K-M-R-E-G-M-P-M-G-V-K-V-T-L-R-G-N-Q-M-Y-N-F-L-E-K-L-I-S-I-A-L-P-R-V-K-D-F-R-G-V-P-R-N-G-F-D-G-R-G-N-Y-S-F-G-L-N-E-Q-L-M-F-P-E-V-V-Y-D-D-I-M-V-S-H-G-M-N-I-T-M-V-T-T-T-N-N-D-K-E-A-F-K-M-L-E-L-F-G-M-P-F-A-K-G-R-V-N-G


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-N-D-I-I-A-D-S-L-T-R-I-R-N-A-A-M-R-R-L-D-Y-T-T-L-Y-Y-A-K-I-V-V-S-I-L-E-V-F-L-A-K-G-F-I-E-S-Y-K-V-I-D-K-D-G-K-Q-S-I-N-V-V-L-K-Y-D-E-K-G-R-S-V-I-S-E-I-K-R-I-S-K-S-G-R-R-V-Y-K-G-R-D-E-L-K-R-F-K-N-G-Y-G-T-I-V-V-S-T-S-K-G-V-I-G-N-E-E-A-Y-K-A-N-V-G-G-E-A-L-C-S-I-W


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-R-P-I-S-I-P-S-G-V-D-A-K-I-E-G-S-K-I-V-F-T-K-G-K-Q-E-K-V-L-E-T-Y-G-R-V-G-L-E-I-A-N-G-E-L-V-L-K-L-G-G-E-D-A-Q-S-K-A-Y-W-G-T-Y-R-A-L-A-N-N-I-V-I-G-L-S-A-G-F-T-K-Q-L-E-I-N-G-V-G-Y-K-A-A-V-K-G-S-V-L-E-L-A-L-G-F-S-H-P-V-N-Y-E-I-P-E-G-V-E-I-A-V-E-K-N-V-I-T-I-K-G-S-D-K-Q-Q-I-G-Q-I-A-A-E-I-R-E-F-R-P-P-E-P-Y-K-G-K-G-V-K-Y-S-D-E-T-I-I-R-K-A-G-K-T-S-K-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-L-E-K-V-L-K-R-K-N-A-L-R-A-K-R-K-L-R-V-R-G-K-I-F-G-T-A-Q-K-P-R-V-S-L-F-R-S-N-R-Y-L-Y-A-Q-A-I-N-D-E-S-G-L-T-L-A-S-V-D-G-K-K-L-G-L-G-N-N-K-E-E-A-K-K-I-A-A-S-F-A-A-S-L-Q-E-A-G-I-K-E-V-V-F-D-R-N-G-Y-L-Y-H-G-V-V-A-S-F-A-D-S-L-R-E-N-G-I-G-L


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-E-I-N-R-D-E-F-K-E-V-V-V-N-I-G-R-V-T-K-V-V-K-G-G-R-R-F-R-F-N-A-L-V-V-V-G-N-K-N-G-L-V-G-F-G-L-G-K-A-K-E-V-P-D-A-I-K-K-A-V-D-D-A-F-K-N-I-I-K-V-N-V-K-G-T-T-I-A-H-D-I-E-H-K-Y-N-A-S-K-I-L-L-K-P-A-S-E-G-T-G-V-I-A-G-G-S-A-R-P-V-I-E-L-A-G-I-K-D-I-L-T-K-S-L-G-S-N-N-P-Y-N-V-V-R-A-T-I-D-A-L-S-R-I-K-A


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-L-E-N-L-K-P-A-Q-G-S-T-K-D-R-K-R-V-G-R-G-Q-G-S-G-M-G-K-T-S-T-R-G-G-K-G-Q-T-A-R-T-G-Y-K-A-K-R-G-F-E-G-G-Q-Q-P-L-Q-R-R-L-P-K-V-G-F-T-T-Q-I-A-K-P-Y-V-I-N-V-E-K-I-T-K-V-A-E-L-A-E-I-T-L-D-S-I-A-S-V-H-K-F-P-A-S-T-L-K-I-K-L-I-G-K-G-A-S-E-L-A-S-K-I-K-D-E-R-I-T-T-S-G-R-A


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-E-V-D-G-K-V-I-E-A-L-P-N-A-T-F-R-V-E-L-D-N-K-H-V-I-L-C-H-I-A-G-R-M-R-M-H-Y-I-K-I-L-P-G-D-R-V-K-I-E-L-T-P-Y-S-L-D-K-G-R-I-T-F-R-Y-K


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-L-P-K-K-K-R-I-E-Y-A-L-T-Y-I-Y-G-I-G-L-K-T-S-R-D-I-L-S-A-V-N-I-S-L-D-K-R-V-Q-E-L-S-E-D-E-V-S-L-I-S-K-K-I-Q-E-S-Y-A-V-E-G-D-L-R-K-K-V-T-M-D-I-K-A-L-M-D-L-G-S-Y-R-G-L-R-H-R-K-G-L-P-V-R-G-Q-T-T-K-N-N-A-R-T-R-K-G-K-R-K-T-V-G-S-A-S-K


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-R-K-V-T-N-K-K-R-V-V-K-K-N-I-A-R-G-I-I-H-I-A-A-T-F-N-N-T-S-V-T-I-T-D-E-M-G-N-V-I-C-W-S-T-A-G-A-L-G-F-K-G-S-K-K-S-T-P-Y-A-A-Q-Q-A-V-E-D-A-V-V-K-A-K-E-H-G-I-K-E-L-G-I-K-V-Q-G-P-G-S-G-R-E-T-A-V-K-S-L-G-S-I-E-G-I-K-V-L-W-F-K-D-V-T-P-L-P-H-N-G-C-R-P-P-K-R-R-R-V


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-S-V-L-D-E-N-Q-K-Q-F-L-L-D-S-I-R-N-I-P-D-F-P-K-P-G-I-Q-F-K-D-I-T-T-L-L-N-D-P-K-A-F-G-F-L-I-D-F-L-T-D-R-Y-A-R-F-E-L-D-Y-V-A-G-I-E-S-R-G-F-I-F-G-A-A-L-A-A-K-L-E-V-G-F-V-P-I-R-K-K-G-K-L-P-S-T-T-I-A-E-K-Y-S-L-E-Y-G-F-D-E-V-E-I-H-I-D-A-F-R-E-K-E-G-S-R-V-L-L-I-D-D-L-I-A-T-G-G-T-A-E-A-A-V-K-L-I-Q-S-A-K-G-H-C-V-E-A-C-F-L-L-N-L-E-E-L-G-G-A-K-K-V-S-N-L-A-P-L-Y-T-L-L-D-I


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-L-L-T-K-E-V-K-G-L-G-K-A-G-E-I-H-E-V-K-D-G-Y-G-R-N-F-L-V-G-K-G-M-A-E-I-A-T-N-E-V-I-N-R-W-K-A-E-Q-K-R-R-A-E-K-E-A-Q-E-L-E-R-L-K-N-V-A-K-E-L-A-S-V-T-L-K-I-V-Q-K-V-G-A-N-G-S-L-Y-G-A-I-T-K-E-D-L-S-A-A-L-M-A-Q-K-G-I-E-V-D-K-K-S-F-E-L-K-T-P-I-K-S-T-G-I-Y-E-I-E-V-K-L-G-H-G-I-H-A-E-L-K-I-D-V-E-G-S-N-V


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-Y-S-M-S-D-L-K-K-G-L-K-V-E-I-E-G-V-P-Y-K-I-V-E-Y-Q-H-V-K-P-G-K-G-A-A-F-V-R-V-K-M-K-S-F-F-D-G-R-V-L-E-K-T-F-H-A-G-D-K-C-E-E-P-N-L-Q-E-K-N-M-Q-Y-L-Y-H-D-G-D-H-F-Q-F-M-D-V-E-S-Y-E-Q-I-A-L-S-D-E-Q-V-G-D-V-A-K-W-M-T-D-G-M-T-V-S-I-L-F-H-N-N-K-A-I-S-V-D-V-P-Q-V-V-E-L-K-I-T-E-T-P-P-N-F-K-G-D-T-S-S-G-S-K-K-P-A-T-L-E-T-G-A-V-I-Q-I-P-Y-H-V-L-E-G-D-V-V-R-V-N-T-E-L-G-E-Y-I-E-K-V-K


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-I-E-L-T-A-L-A-I-A-L-S-M-D-A-V-A-V-S-I-A-L-G-S-K-C-E-E-E-I-R-Q-L-A-L-K-A-G-G-F-F-G-V-A-Q-M-V-M-P-L-L-G-F-Y-L-G-V-Q-L-H-D-Y-I-G-G-I-H-H-W-V-A-L-G-V-L-G-F-L-G-L-K-M-I-R-E-A-T-Q-G-E-K-E-L-A-L-S-S-H-P-S-S-S-K-L-L-L-L-A-F-V-T-S-L-D-A-M-A-A-G-L-T-L-T-L-L-G-L-P-L-W-F-C-L-L-F-I-G-G-S-T-F-L-L-S-F-G-G-V-H-L-G-R-K-S-G-T-Y-L-E-E-K-A-E-Y-L-G-G-I-I-L-I-L-I-G-V-K-I-F-I-E-H-S


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-D-S-A-I-K-L-E-I-I-S-K-F-A-R-G-E-K-D-T-G-S-P-E-V-Q-V-A-L-L-S-R-R-I-S-D-L-T-E-H-L-K-V-N-V-K-D-H-A-S-R-L-G-L-L-K-L-V-A-Q-R-K-H-L-L-K-Y-L-K-K-T-D-Y-A-K-Y-S-E-L-I-S-T-L-G-I-R-D-R


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-R-K-V-I-A-N-N-K-K-A-L-F-D-F-H-I-L-E-R-L-E-A-G-I-A-L-S-G-S-E-V-K-A-I-R-A-G-R-V-N-L-K-D-S-F-V-K-I-I-K-G-E-A-F-L-L-N-A-H-I-S-Y-L-E-T-T-N-P-H-Y-K-P-D-E-R-R-P-R-K-L-L-L-H-R-K-Q-I-D-K-L-T-G-S-V-S-T-E-G-M-T-L-V-T-L-S-I-Y-F-N-E-R-N-R-A-K-A-E-I-A-L-A-K-G-K-N-L-H-D-K-R-E-T-L-K-K-R-I-L-D-R-E-V-K-A-A-L-K-E-H


### FUNCTION Specifically methylates the N7 position of guanine in position 527 of 16S rRNA ### SEQUENCE -M-S-S-L-K-H-Q-L-K-T-Y-H-I-P-F-D-D-Q-M-L-E-R-L-E-R-Y-T-A-L-L-L-E-W-N-R-A-H-N-L-T-G-A-K-N-S-Q-E-V-E-E-H-L-I-D-S-L-Y-P-L-R-F-L-P-P-F-D-S-C-A-D-I-G-T-G-A-G-F-P-G-L-I-L-A-I-A-L-P-K-S-H-F-D-L-I-E-P-L-K-K-R-V-A-F-L-H-Y-C-V-M-E-L-G-L-S-N-V-S-I-H-A-K-R-I-E-A-L-T-L-E-A-P-D-L-I-T-S-R-A-V-T-S-T-Q-T-L-L-S-L-A-R-P-L-I-A-P-H-T-S-I-L-F-Y-K-G-E-R-V-L-G-E-I-Q-E-E-E-G-Y-T-I-T-P-F-K-Q-R-R-Y-L-F-K-Q-G-V


### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate  with acetyl coenzyme A ### SEQUENCE -M-F-R-P-P-S-I-K-D-A-K-K-I-W-E-L-I-G-R-C-K-P-L-D-I-N-S-P-Y-C-Y-A-L-I-G-R-D-F-F-D-S-S-I-V-Y-E-E-E-G-R-I-K-G-V-V-I-G-Y-L-R-P-R-A-P-E-R-L-F-V-W-Q-V-A-I-E-A-K-S-R-G-K-G-I-A-K-R-A-I-E-A-I-L-K-N-L-E-R-K-G-H-C-I-Q-A-I-E-A-T-Y-T-P-S-N-L-A-S-K-A-L-F-H-A-L-G-R-E-W-K-V-V-W-I-E-E-N-F-L-E-G-A-L-L-S-A-Q-E-A-H-E-E-E-W-L-I-T-L-P-F-S-S-E-A-L-G-V-Q-G-A-N-H-A-N-L


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-T-G-T-V-R-R-Q-R-H-K-K-V-L-K-L-A-R-G-F-Y-S-G-R-R-K-H-F-R-K-A-K-E-Q-L-E-R-S-M-Y-Y-A-F-R-D-R-K-Q-K-K-R-D-F-R-S-L-W-I-T-R-I-N-A-A-C-R-I-N-E-I-S-Y-S-R-F-M-H-G-L-K-L-A-N-I-E-L-D-R-K-I-L-A-D-M-A-M-N-E-P-A-N-F-A-K-I-V-E-A-A-K-K-A-L


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-K-N-N-D-T-T-L-L-N-E-E-I-R-F-P-E-V-R-C-L-G-D-E-G-T-Q-Y-G-V-V-S-S-S-E-A-L-K-I-A-Q-D-L-G-L-D-L-V-L-I-A-P-E-A-K-P-P-V-C-K-I-M-D-Y-G-K-F-R-Y-Q-Q-E-K-K-Q-K-E-A-K-K-K-Q-K-Q-I-E-I-K-E-I-K-L-S-V-K-I-A-Q-N-D-V-N-Y-K-V-K-H-A-K-E-F-L-E-E-D-K-H-V-R-F-R-V-F-L-K-G-R-E-M-S-E-P-Q-S-G-V-E-V-L-K-R-V-W-E-L-V-E-D-I-A-I-M-D-K-E-P-K-P-E-G-R-Y-V-N-M-T-V-I-P-K-P-K-K-V-K


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-K-S-A-E-K-R-I-R-Q-T-L-K-R-T-E-R-N-R-Y-Y-R-T-R-I-K-N-I-T-K-A-V-K-E-A-V-A-S-N-D-A-T-K-A-E-E-A-L-K-V-A-N-K-D-L-H-K-F-V-S-K-G-I-L-P-K-N-T-A-A-R-K-V-S-R-L-H-A-S-V-K-K-L-S-A-Q-I-A


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-S-E-L-K-K-M-K-I-R-L-L-K-L-H-P-N-A-V-I-P-A-Y-Q-S-A-G-A-A-G-F-D-L-C-C-V-E-S-L-E-I-P-P-L-G-R-A-L-V-S-T-G-L-A-L-A-L-E-E-G-Y-E-L-Q-I-R-P-R-S-G-L-A-L-K-H-G-I-T-V-L-N-T-P-G-T-V-D-S-D-Y-R-G-E-I-K-V-I-L-I-N-L-G-A-E-S-F-S-I-Q-A-G-D-R-I-A-Q-G-V-V-S-R-L-S-I-A-E-L-C-E-V-E-S-L-D-E-T-A-R-G-A-G-G-F-G-S-T-G-K-S


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-Q-K-E-P-M-T-I-Y-G-Y-E-K-L-Q-R-E-L-K-E-L-K-E-V-E-R-P-Q-I-V-K-E-I-D-I-A-R-G-H-G-D-L-K-E-N-A-E-Y-H-A-A-K-E-R-Q-L-F-I-E-A-R-I-N-E-L-S-E-I-L-S-R-T-Q-V-V-D-P-A-T-I-T-H-E-K-I-S-F-G-S-T-F-K-V-M-D-L-D-T-E-F-V-Y-E-Y-T-I-V-G-A-P-E-S-N-P-D-R-G-F-I-S-F-Y-S-P-L-A-R-Q-L-I-G-K-V-P-G-D-E-I-N-A-K-L-P-N-G-E-I-D-Y-E-V-L-E-V-Y-Y-K-E-I-S-F-E


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-I-F-D-D-I-K-E-V-V-V-E-Q-L-N-V-N-P-E-E-V-K-E-E-S-K-F-V-E-D-L-G-A-D-S-L-D-V-V-E-L-V-M-A-L-E-E-K-F-N-I-E-I-P-D-E-E-A-E-K-I-A-T-V-G-D-V-V-R-Y-I-E-T-N-K


### FUNCTION Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis ### SEQUENCE -M-Y-V-A-I-E-G-V-D-T-C-G-K-S-T-Q-I-A-L-L-K-R-R-F-P-G-A-I-F-T-K-E-P-G-G-T-A-L-G-M-K-L-R-E-L-L-L-G-G-E-A-K-S-A-K-A-E-L-L-L-F-L-A-D-R-A-E-H-M-E-L-V-I-K-P-A-L-D-K-L-L-F-S-D-R-S-L-I-S-G-M-A-Y-A-K-G-W-D-E-L-W-L-K-S-L-N-L-F-A-T-E-G-I-V-P-D-K-V-V-I-L-E-L-T-A-K-E-L-S-Y-R-L-S-Q-K-S-H-D-S-I-E-S-R-G-V-E-Y-L-L-E-L-Q-E-R-I-K-Q-M-T-A-L-L-G-I-P-S-L-T-L-S-A-S-L-S-P-E-E-I-H-G-R-I-V-S-G-F-V-L-K-G


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-R-N-R-Y-I-E-S-F-E-K-A-Q-I-A-D-K-N-I-P-Q-F-K-A-G-D-T-L-R-V-G-V-K-I-Q-E-G-D-K-T-R-V-Q-N-F-E-G-I-C-I-S-V-R-G-T-G-T-G-K-T-F-T-I-R-K-M-G-A-N-N-V-G-V-E-R-I-F-P-L-Y-S-D-S-L-E-S-V-T-L-L-R-V-G-R-V-R-R-A-K-L-Y-Y-L-R-D-R-S-G-K-S-A-R-I-K-E-L-R-K


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-R-E-L-V-A-K-R-Y-A-K-A-L-V-E-A-L-G-E-D-R-L-A-S-T-L-E-W-L-K-G-S-E-S-A-F-G-T-E-A-F-Q-E-M-L-A-S-P-Q-I-S-K-T-L-K-G-Q-V-V-L-D-V-L-G-D-G-E-A-K-L-L-N-F-I-K-V-L-A-D-K-N-R-L-E-L-I-P-D-V-C-K-E-L-E-K-S-I-A-A-T-R-N-E-Y-V-A-V-L-T-T-Q-E-A-F-D-D-K-T-L-K-A-I-E-E-T-L-A-K-K-L-Q-A-K-L-V-L-S-Q-K-R-E-E-F-E-G-V-K-L-V-V-E-D-L-G-V-E-V-S-F-S-R-E-R-F-I-N-D-L-K-N-H-I-L-K-A-F


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-G-K-Y-F-I-P-C-L-L-L-P-T-M-M-L-A-S-G-G-G-G-E-T-D-I-V-E-R-T-I-N-F-V-I-F-I-A-I-F-Y-Y-L-A-A-D-K-I-K-A-I-F-V-A-R-Q-E-S-I-A-A-E-L-E-K-V-Q-E-K-L-K-E-S-K-K-A-K-E-Q-A-Q-K-R-F-E-E-S-K-R-M-A-E-D-V-I-L-T-A-K-K-E-V-V-L-L-T-Q-K-V-E-D-S-T-K-G-D-I-E-N-L-I-R-Q-Y-N-D-S-M-E-F-E-K-R-K-A-E-R-A-I-I-D-E-I-L-A-E-L-F-E-S-D-A-T-K-L-D-K-S-A-Y-S-E-I-L-L-K-K-V-A


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-K-N-G-G-K-Q-Y-K-V-Q-E-G-D-I-V-L-F-D-K-M-S-L-E-P-K-S-K-V-E-L-N-E-V-L-A-L-C-K-D-D-N-L-I-L-G-T-P-F-V-E-G-A-K-I-E-I-E-V-I-N-E-D-R-A-K-K-V-V-T-F-K-K-R-R-R-K-D-S-K-T-K-R-G-F-R-R-D-F-T-R-V-R-I-L-K-I-A-A


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-D-N-P-A-N-A-E-P-Q-E-E-E-V-S-L-E-S-Q-P-S-T-P-E-S-G-S-D-G-S-K-E-A-E-L-E-A-K-I-K-E-L-E-D-S-Y-L-R-V-H-A-D-F-E-N-T-K-K-R-L-E-R-E-K-F-Q-A-L-E-Y-A-Y-E-K-I-A-K-D-L-L-P-I-V-D-T-L-E-I-A-L-K-S-A-N-E-V-S-G-E-E-S-E-L-Q-A-K-F-K-E-G-L-E-L-T-L-D-N-F-S-K-V-L-Q-R-H-G-I-E-M-I-A-C-E-G-E-F-D-P-H-L-H-E-C-I-M-Q-V-P-S-P-S-H-Q-E-G-E-I-V-Q-V-F-Q-K-G-Y-R-Y-K-E-R-V-L-R-P-A-M-V-S-I-A-K-S-N


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-R-R-K-A-P-V-R-E-V-L-G-D-P-I-Y-G-N-K-V-V-T-K-F-V-N-K-M-M-Y-D-G-K-K-S-V-A-E-K-I-I-Y-A-T-F-D-R-I-E-E-K-T-K-E-K-G-I-E-V-F-E-K-A-L-E-R-V-R-P-M-V-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-A-T-R-Q-Q-S-L-S-I-R-W-L-L-E-A-A-R-K-R-N-E-R-T-M-V-D-R-L-A-N-E-L-I-D-A-A-N-D-R-G-S-A-F-K-K-K-E-D-V-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-I-R-K-E-R-K-K-A-I-K-K-S-K-S-P-A-L-V-N-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-V-R-L-T-S-G-F-E-V-I-S-Y-I-P-G-E-G-H-N-L-Q-E-H-S-I-V-L-I-R-G-G-R-V-K-D-L-P-G-V-K-Y-H-I-I-R-G-A-L-D-T-A-G-V-Q-K-R-N-V-S-R-S-K-Y-G-A-K-K-G-K-A-G-A-A-P-T-T-G-K-K-K


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-I-T-K-E-E-L-L-D-Y-I-G-G-L-S-V-L-E-L-S-E-L-V-K-A-F-E-E-K-F-G-V-S-A-A-P-T-V-V-A-G-A-G-A-G-V-A-A-A-A-V-E-E-K-T-E-F-D-V-I-L-L-D-G-G-E-K-K-I-N-V-I-K-V-V-R-E-L-T-G-L-G-L-K-E-A-K-D-A-V-E-K-T-P-T-T-I-K-E-G-A-N-K-D-D-A-A-A-M-K-A-K-L-E-E-A-G-A-K-V-E-I-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-T-K-T-E-K-T-Q-I-I-E-T-L-T-A-E-F-K-A-S-S-A-I-A-V-C-D-Y-K-G-L-T-V-R-Q-F-E-A-L-R-R-A-A-R-D-N-G-A-K-V-Q-V-V-K-N-T-L-A-G-I-A-L-E-N-A-D-A-K-G-L-E-L-K-E-T-N-V-F-V-W-S-D-D-Q-I-A-L-S-K-T-I-M-K-F-A-E-T-S-N-E-K-F-K-V-K-F-G-Y-Y-E-G-S-V-V-D-A-A-H-I-E-T-V-S-K-L-P-S-R-D-E-L-I-G-M-L-L-S-V-W-T-A-P-A-R-Y-F-V-T-A-L-D-N-L-K-K-Q-K-E-E-N


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-V-A-L-K-G-N-I-E-K-K-E-P-T-R-L-W-L-E-V-G-G-V-T-Y-E-I-F-I-S-I-H-T-S-A-A-L-G-E-K-E-A-R-L-L-I-T-H-L-I-R-E-E-A-W-S-L-Y-G-F-A-E-E-A-E-K-R-V-F-D-T-L-I-K-I-N-G-V-G-P-K-A-A-L-A-I-L-S-T-Y-T-P-P-T-F-A-Q-I-I-Q-A-Q-D-V-K-A-L-Q-R-V-P-G-I-G-P-K-S-A-G-R-I-M-V-E-L-A-G-F-S-L-S-L-Q-E-G-S-K-A-S-T-P-P-V-F-E-E-S-R-L-A-L-E-S-L-G-F-K-S-E-L-I-A-K-A-L-Q-N-I-Q-A-T-T-T-Q-E-I-I-K-E-A-L-K-K-L-Q-T-L-R


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-E-L-N-E-V-Y-Q-Y-T-K-E-H-M-E-K-T-I-D-A-M-K-R-D-F-A-T-L-R-T-G-K-V-S-T-A-I-V-E-P-I-R-V-D-Y-Y-G-T-P-T-P-L-S-Q-V-G-S-V-I-A-S-D-A-T-T-L-V-I-S-P-W-E-K-N-L-L-K-G-I-E-K-A-I-Q-E-A-N-I-G-V-N-P-N-N-D-G-D-V-I-K-L-F-F-P-P-M-T-S-E-Q-R-K-E-I-A-K-D-A-K-A-L-G-E-K-A-K-V-A-V-R-N-I-R-K-E-S-N-D-K-I-K-K-L-E-K-D-K-L-I-T-E-D-Q-S-K-K-A-H-D-E-V-Q-K-Y-T-D-D-Y-V-K-K-I-D-D-M-V-K-S-K-E-E-E-I-L-K-V


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-F-K-P-L-G-Q-R-V-L-V-E-R-L-E-E-D-T-K-T-A-S-G-I-I-I-P-D-N-A-K-E-K-P-L-M-G-T-V-K-A-L-S-E-E-V-A-K-E-G-L-L-K-A-G-S-Q-V-V-F-A-K-Y-S-G-T-D-V-K-L-E-G-K-E-Y-L-I-L-K-V-E-D-L-L-G-T-I-E


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-A-T-R-A-Q-A-R-E-A-V-V-S-L-L-Y-A-Y-D-M-G-N-T-E-I-R-K-F-A-I-E-L-L-E-E-K-R-I-K-N-R-Q-Q-E-F-A-L-E-L-F-D-G-T-I-A-H-L-G-E-I-D-E-E-I-K-K-H-L-K-E-W-D-F-S-R-I-G-D-M-E-R-A-I-L-R-L-G-T-F-E-I-V-Y-S-G-V-D-R-A-V-I-I-N-E-A-V-E-L-S-K-T-F-G-N-D-N-S-P-R-F-V-N-G-V-L-D-A-L-R-P-D-L-K-K-G


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-N-V-I-E-G-K-L-N-L-T-G-N-E-R-V-A-V-I-A-S-R-F-N-H-L-I-T-D-R-L-V-E-G-A-R-D-S-F-V-R-H-G-G-K-D-E-H-L-D-L-I-L-V-P-G-A-F-E-L-P-F-A-L-E-K-V-L-A-Q-G-D-Y-D-G-V-C-C-L-G-A-I-I-R-G-S-T-P-H-F-D-Y-V-S-A-E-A-T-K-G-I-A-N-V-T-L-K-Y-G-A-A-V-T-F-G-V-L-T-T-D-N-I-E-Q-A-I-E-R-A-G-T-K-V-G-N-K-G-F-E-A-M-T-G-L-I-E-M-M-N-L-Y-K-N-I-G-A


### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-L-Y-D-V-Q-K-I-K-E-I-L-P-H-R-F-P-F-L-L-V-D-R-V-T-A-L-T-S-E-E-S-I-E-A-Y-K-N-I-T-I-N-E-E-V-F-Q-G-H-F-P-I-K-P-V-Y-P-G-V-L-V-I-E-G-M-A-Q-A-G-G-V-L-A-F-V-S-M-F-G-E-E-A-S-N-H-D-E-K-I-V-Y-F-M-S-I-D-K-A-K-F-R-V-P-V-T-P-G-D-K-L-V-Y-R-L-N-V-L-K-H-K-G-S-I-W-I-L-E-G-R-A-Y-V-D-D-K-L-V-A-E-A-E-L-K-A-M-V-A-D-K-E-K


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-M-K-K-I-D-V-K-I-L-D-P-R-I-G-E-E-F-P-L-P-T-Y-A-T-P-G-S-A-G-L-D-L-R-A-C-L-D-N-A-V-E-L-A-P-G-Q-T-E-L-L-P-T-G-L-A-I-H-I-G-D-E-Q-L-A-A-V-I-L-P-R-S-G-L-G-H-K-H-G-V-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-Q-L-M-V-S-V-W-N-R-G-D-K-A-F-T-I-Q-P-G-E-R-I-A-Q-I-V-F-V-P-V-V-Q-A-E-F-N-L-V-E-D-F-E-T-S-E-R-G-S-G-G-F-G-H-S-G-R-Q


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-K-R-K-E-V-E-S-K-S-A-G-G-I-V-L-T-G-T-A-A-G-K-S-T-R-G-E-V-L-A-V-G-N-G-R-I-L-E-S-G-D-V-K-A-L-C-V-K-V-G-D-I-V-I-F-N-D-G-Y-G-V-K-S-E-K-I-D-N-E-E-V-L-I-M-S-E-S-D-I-L-A-I-V-E-A


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-Q-A-V-I-D-V-K-I-L-D-A-R-L-R-D-N-L-P-A-Y-A-T-A-G-S-A-G-L-D-L-R-A-A-T-E-E-T-M-T-I-Q-P-G-E-T-Q-L-V-P-T-G-I-A-I-H-L-S-D-P-G-L-A-A-M-L-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-Q-M-F-V-S-V-W-N-R-G-Q-Q-P-F-R-L-E-P-M-E-R-I-A-Q-M-V-I-V-P-V-V-Q-A-S-F-N-I-V-D-D-F-D-A-S-D-R-G-A-G-G-F-G-S-T-G-R-G


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-V-L-E-I-L-T-A-P-D-P-R-L-R-V-Q-S-K-E-V-T-D-V-A-A-V-Q-T-L-I-D-D-L-L-E-T-L-Y-E-T-D-N-G-V-G-L-A-A-P-Q-V-G-R-E-E-A-I-V-V-I-D-L-S-E-N-R-D-E-P-L-V-L-V-N-P-K-V-V-S-G-S-N-K-E-M-G-Q-E-G-C-L-S-V-P-D-Y-Y-A-D-V-E-R-Y-T-S-V-V-V-E-A-L-D-R-N-G-K-E-L-R-I-E-T-S-E-F-L-A-I-V-M-Q-H-E-I-D-H-L-S-G-N-L-F-I-D-Y-L-S-P-L-K-Q-Q-M-A-M-K-K-V-K-K-H-N-K-L-R-A-R


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-D-K-T-L-K-F-T-E-S-H-E-W-V-R-D-N-G-D-G-T-V-T-I-G-I-S-E-H-A-Q-E-M-L-G-D-V-V-F-V-E-L-P-E-L-E-A-E-I-E-A-G-E-S-F-S-L-V-E-S-V-K-A-A-S-D-I-Y-A-P-V-T-G-E-V-V-E-V-N-E-E-L-S-D-S-P-E-L-I-N-E-E-P-Y-E-G-G-W-I-V-K-V-K-L-S-D-P-S-E-L-D-N-L-K-D-A-E-E-Y-L-N-S-I-E-E-D


### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-Q-K-T-T-R-T-M-P-A-H-K-H-I-A-L-V-A-H-D-N-Y-K-P-E-L-L-R-W-V-K-E-N-K-E-K-L-Q-S-H-F-L-Y-A-T-G-T-T-G-H-M-L-S-R-E-T-G-L-A-I-K-S-M-I-S-G-P-M-G-G-D-Q-Q-L-G-A-L-I-S-E-G-K-I-D-M-L-I-F-F-W-D-P-L-N-A-V-P-H-D-P-D-V-K-A-L-L-R-I-A-S-V-W-N-I-P-V-A-T-N-R-A-T-A-K-F-L-F-E-S-P-L-L-N-E-E-V-D-V-E-I-P-D-Y-Q-A-Y-L-A-G-R-T


### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-T-A-P-T-K-M-T-F-F-S-R-F-E-A-D-I-L-A-G-K-K-T-I-T-I-R-D-E-S-E-K-D-Y-Q-P-G-T-T-V-E-V-S-T-L-E-E-G-R-V-F-C-Q-L-K-I-L-S-V-E-P-I-A-F-S-E-L-N-E-F-H-A-E-Q-E-N-M-T-L-A-T-L-K-E-V-I-Q-E-I-Y-P-G-I-E-Q-L-Y-V-I-Q-Y-Q-R-V


### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-V-G-M-P-K-I-R-R-P-Q-L-V-S-A-T-M-T-V-I-D-R-V-G-L-H-G-A-S-V-S-L-I-S-Q-E-A-G-V-S-S-G-I-I-N-H-Y-F-G-G-K-H-G-L-L-E-E-T-M-R-D-I-L-R-Q-L-S-C-D-A-T-K-R-L-N-S-L-P-K-Q-A-H-M-Q-R-I-N-A-I-L-D-A-N-F-V-G-F-Q-S-E-S-K-V-I-K-T-W-L-A-F-W-S-Y-S-M-H-D-E-A-L-K-R-L-Q-R-V-N-E-K-R-L-L-S-H-L-K-R-E-L-K-A-L-M-S-K-E-Q-A-D-I-V-A-Q-G-I-A-A-L-I-D-G-I-W-L-R-G-A-L-N-P-E-G-I-N-A-N-K-A-R-I-I-I-N-D-Y-L-E-K-Q-L-T-F-Y-S-Q-Q


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-M-N-A-T-L-L-G-Q-A-I-S-F-A-M-F-V-W-F-C-M-K-Y-V-W-P-P-I-M-Q-A-I-E-E-R-Q-K-K-I-A-D-G-L-Q-A-A-E-R-A-A-K-D-L-D-L-A-Q-A-N-A-S-S-Q-L-K-E-A-K-R-T-A-T-E-I-I-E-Q-A-N-K-R-K-A-Q-I-L-D-E-A-R-E-D-A-Q-T-E-R-Q-K-I-L-A-Q-A-E-A-Q-L-E-A-E-R-N-R-A-R-D-E-L-R-K-Q-V-A-T-L-A-V-A-G-A-E-K-I-L-E-R-S-I-D-K-D-A-H-K-D-I-L-D-N-I-T-A-K-L


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-D-F-T-T-I-A-R-P-Y-A-K-A-A-F-D-F-A-V-E-K-G-Q-L-D-Q-W-G-Q-M-L-S-F-A-A-E-V-A-Q-N-E-Q-I-S-E-L-L-S-G-S-M-S-A-D-K-L-A-E-L-F-I-A-I-C-G-E-Q-V-D-E-F-G-Q-N-L-L-K-V-M-A-E-N-G-R-L-A-A-L-P-D-V-C-T-L-F-F-V-L-K-K-E-H-E-K-E-I-D-V-E-V-I-S-A-T-E-L-S-D-E-Q-C-A-N-I-S-Q-K-L-E-Q-R-L-E-R-K-V-K-L-N-C-S-V-D-E-A-L-L-G-G-V-I-I-R-A-G-D-L-V-I-D-N-S-A-R-G-R-L-N-R-L-S-D-A-L-Q-S


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-A-I-T-F-H-L-D-V-V-S-A-E-K-K-I-F-S-G-R-V-E-T-F-Q-V-T-G-S-E-G-E-L-G-I-F-H-G-H-T-P-L-L-T-A-I-K-P-G-M-V-R-I-V-K-L-H-G-E-E-E-F-I-Y-V-S-G-G-I-V-E-V-Q-P-G-T-A-T-V-L-A-D-T-A-I-R-G-E-E-L-D-A-A-K-A-E-E-A-K-R-R-A-K-E-N-I-L-N-Q-H-G-D-M-D-F-A-Q-A-A-S-E-L-A-K-A-I-A-Q-L-R-V-I-E-L-T-K-K-R-R


### FUNCTION Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide ### SEQUENCE -M-K-V-G-I-I-M-G-S-K-S-D-W-P-T-M-K-L-A-A-E-M-L-D-R-F-G-V-E-Y-E-T-K-V-V-S-A-H-R-T-P-H-L-L-A-E-Y-A-S-T-A-K-E-R-G-L-K-V-I-I-A-G-A-G-G-A-A-H-L-P-G-M-A-A-A-F-T-S-L-P-V-L-G-V-P-V-Q-S-R-A-L-S-G-L-D-S-L-Y-S-I-V-Q-M-P-K-G-I-A-V-G-T-L-A-I-G-E-A-G-A-A-N-A-G-L-L-A-A-Q-I-L-G-T-H-D-E-N-I-M-A-K-V-E-A-F-R-S-E-Q-T-E-S-V-L-A-N-P-N-P-A-E-D


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-S-Q-F-A-I-L-G-F-I-A-L-G-G-A-F-G-A-C-S-R-Y-L-V-S-E-L-C-V-V-L-L-G-R-G-F-P-Y-G-T-L-T-V-N-V-V-G-S-F-I-M-G-L-L-I-A-A-F-E-S-E-L-L-A-T-E-P-W-R-Q-I-I-G-L-G-F-L-G-A-L-T-T-F-S-T-F-S-M-D-N-V-L-L-M-Q-Q-G-A-F-F-K-M-G-L-N-V-V-L-N-V-T-L-S-I-T-A-A-W-V-G-F-Q-L-L-K-S


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-Q-D-K-K-A-I-V-A-E-V-N-E-A-A-A-G-A-L-S-A-V-V-A-D-S-R-G-V-S-V-D-A-M-T-T-L-R-K-Q-A-R-E-A-G-V-Y-M-K-V-V-R-N-T-L-A-R-R-A-V-E-G-T-Q-Y-E-C-L-T-D-T-F-T-G-P-S-L-I-A-F-S-N-E-H-P-G-A-A-A-R-L-F-K-D-F-A-K-E-N-K-K-F-E-I-K-A-A-A-F-E-G-A-L-T-D-A-E-V-L-A-T-L-P-T-Y-D-E-A-I-A-R-L-M-M-C-L-K-E-A-S-A-G-K-L-V-R-T-I-A-A-I-R-D-Q-K-E-A-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-I-T-N-E-Q-I-L-D-A-I-A-E-M-S-V-T-Q-V-V-E-L-I-S-A-M-E-E-K-F-G-V-T-A-A-A-A-V-V-A-G-G-A-A-A-G-A-A-V-E-E-Q-T-E-F-N-V-I-L-A-S-A-G-A-N-K-V-A-V-I-K-A-V-R-G-A-T-G-L-G-L-K-E-A-K-A-L-V-D-G-A-P-A-A-L-K-E-G-V-E-K-A-E-A-E-A-L-K-K-E-L-E-E-A-G-A-T-V-E-I-K


### FUNCTION Activates ribosomal RNA transcription Plays a direct role in upstream activation of rRNA promoters ### SEQUENCE -M-F-E-Q-N-L-T-S-E-A-L-T-V-T-T-V-T-S-Q-D-Q-I-T-Q-K-P-L-R-D-S-V-K-A-S-L-K-N-Y-L-A-Q-L-N-G-Q-E-V-T-E-L-Y-E-L-V-L-A-E-V-E-Q-P-L-L-D-T-I-M-Q-Y-T-R-G-N-Q-T-R-A-A-T-M-M-G-I-N-R-G-T-L-R-K-K-L-K-K-Y-G-M-N


### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-T-V-S-T-N-E-F-K-G-G-L-K-L-M-I-D-S-E-P-C-V-I-L-E-N-E-Y-V-K-P-G-K-G-Q-A-F-N-R-V-K-I-R-K-L-L-S-G-K-V-L-E-K-T-F-K-S-G-D-T-C-E-V-A-D-V-M-D-I-D-L-D-Y-L-Y-S-D-G-E-F-Y-H-F-M-N-N-E-T-F-E-Q-I-A-A-D-A-K-A-V-G-E-N-V-K-W-L-V-E-N-N-T-C-M-L-T-L-W-N-G-N-P-I-A-V-T-P-P-N-F-V-E-L-E-V-I-E-T-D-P-G-L-K-G-D-T-Q-G-T-G-G-K-P-A-T-L-S-T-G-A-V-V-R-V-P-L-F-I-Q-I-G-E-V-I-K-V-D-T-R-S-S-E-Y-V-G-R-V-K


### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-K-P-N-Y-N-V-D-R-A-P-K-R-S-D-E-P-V-W-W-S-L-F-G-A-G-G-T-W-F-A-M-I-T-P-V-T-V-L-V-L-G-I-L-V-P-M-G-V-I-N-A-E-A-L-S-Y-D-R-V-V-S-F-A-T-S-I-I-G-A-L-F-I-I-A-T-L-A-L-P-M-W-H-A-M-H-R-V-H-H-G-M-H-D-L-K-F-H-T-G-V-V-G-K-I-A-C-Y-A-I-A-G-L-I-S-A-L-A-V-V-F-I-F-M-L


### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-S-N-R-K-P-Y-V-R-E-V-K-R-T-W-W-K-D-H-P-F-Y-R-F-Y-M-L-R-E-A-T-V-L-P-L-I-L-F-T-L-F-L-T-V-G-L-G-S-L-V-K-G-P-E-A-W-Q-T-W-L-N-F-M-A-N-P-V-V-I-A-I-N-I-V-A-L-L-G-S-L-L-H-A-H-T-F-F-S-M-M-P-Q-V-M-P-I-R-L-K-G-K-P-V-D-K-K-I-I-V-L-A-Q-W-A-A-V-A-F-I-S-L-I-V-L-I-V-V


### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-A-E-A-A-P-Q-D-T-Q-Q-H-F-A-I-Q-R-I-F-L-K-D-V-S-F-E-A-P-N-S-P-V-M-F-Q-K-E-W-N-P-D-V-K-L-D-L-D-T-Q-S-R-E-L-G-E-G-V-Y-E-V-I-L-R-L-T-V-T-V-K-N-A-E-E-T-A-F-L-C-E-V-Q-Q-G-G-I-F-T-A-E-K-M-E-A-G-Q-L-A-H-C-L-G-A-F-C-P-N-I-L-F-P-Y-A-R-E-T-I-S-S-L-V-V-K-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-M-N-Y-L-Q-Q-Q-A-A-Q-Q-G-A-E-Q-A


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-S-F-S-D-Q-N-L-I-W-I-D-L-E-M-T-G-L-D-P-D-V-H-K-I-I-E-I-A-S-I-V-T-D-S-E-L-N-I-L-A-E-G-P-V-L-A-I-H-Q-S-E-E-E-L-A-K-M-D-E-W-C-T-N-T-H-T-G-S-G-L-V-E-R-V-R-G-S-Q-I-T-E-Q-E-A-V-E-Q-T-I-A-F-L-E-K-W-V-P-K-G-V-S-P-I-C-G-N-S-I-G-Q-D-R-R-F-L-Y-R-H-M-P-E-L-E-G-Y-F-H-Y-R-Y-I-D-V-S-T-L-K-E-L-T-R-R-W-N-P-E-V-L-K-G-F-S-K-Q-G-T-H-L-A-L-D-D-I-R-E-S-I-A-E-L-K-F-Y-R-Q-T-I-F-K-I


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-I-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-N-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-P-V-S-H-H-S-G-E-R-G-S-D-R-P-S-E-K-S-E-D


### FUNCTION Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress May require iron for activity ### SEQUENCE -M-Q-L-T-S-F-T-D-Y-A-L-R-T-L-I-Y-L-A-S-L-P-D-N-E-Q-T-N-I-T-D-V-T-E-L-F-G-V-S-R-N-H-M-V-K-V-I-N-R-L-G-Q-L-N-Y-I-Q-T-V-R-G-K-N-G-G-I-R-L-N-R-P-A-K-T-I-L-V-G-E-V-V-R-D-L-E-P-L-D-L-V-N-C-S-V-E-F-C-H-I-T-P-A-C-R-L-K-E-R-L-Y-R-A-K-L-A-F-L-A-E-L-D-D-C-S-I-A-E-L-L-D-D-N-A-E-L-L-I-L-L-Q-K-A


### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-S-A-L-R-Y-T-L-V-V-N-G-S-V-Y-G-S-Q-S-A-R-T-A-Y-Q-F-A-T-A-L-I-E-K-G-H-T-L-V-S-V-F-F-Y-Q-D-G-V-T-N-G-T-E-L-T-V-P-A-N-D-E-F-H-L-T-K-A-W-Q-Q-L-A-K-Q-H-N-V-R-L-E-T-C-V-A-A-A-L-R-R-G-V-V-S-Q-S-E-A-S-Q-H-G-L-L-Q-H-N-L-A-E-G-F-E-Q-A-G-L-G-S-L-A-E-A-M-L-T-Q-D-R-V-V-Q-F


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-N-Q-L-V-R-K-P-R-A-K-Q-V-V-K-S-N-V-P-A-L-E-A-C-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-T-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-A-L-D-C-A-G-V-N-N-R-K-Q-G-R-S-K-Y-G-V-K-R-P-K-S


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-I-G-Q-R-K-I-L-P-D-P-K-F-K-S-E-L-L-A-K-F-V-N-I-L-M-V-D-G-K-K-S-V-A-E-K-I-V-Y-T-A-L-D-T-M-A-E-K-S-G-K-D-H-L-A-V-F-E-E-A-L-E-N-V-R-P-A-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-P-V-R-R-N-A-L-A-M-R-W-L-V-E-A-A-R-K-R-G-E-K-S-M-A-A-R-L-A-A-E-M-L-D-A-S-D-N-K-G-T-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W


### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-F-E-V-L-E-K-L-E-A-K-I-Q-T-A-V-D-T-I-A-L-L-Q-M-E-V-D-E-L-K-E-D-K-A-K-L-E-T-E-A-N-E-L-R-A-Q-R-E-Q-L-E-Q-K-A-Q-Q-T-Q-Q-E-H-A-Q-W-Q-E-R-I-R-A-L-L-G-K-M-E-D-V-E


### FUNCTION Globally modulates RNA abundance by binding to RNase E  and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome Modulates RNA-binding and helicase activities of the degradosome ### SEQUENCE -M-E-Y-N-T-S-A-L-C-D-I-Y-M-D-Q-V-D-V-V-E-P-M-F-S-N-F-G-G-R-A-S-F-A-G-Q-I-T-T-V-K-C-F-E-D-N-A-L-I-R-E-T-L-E-Q-D-G-V-G-R-V-L-L-V-D-G-G-G-S-L-R-R-A-L-L-D-G-E-L-A-A-I-A-E-E-N-E-W-E-G-I-V-V-Y-G-C-V-R-E-V-D-E-L-E-D-M-N-I-G-I-Q-A-L-A-S-I-P-V-S-A-A-M-Q-G-V-G-E-V-D-V-P-V-N-F-G-G-V-T-F-L-P-E-D-Y-L-Y-A-D-T-T-G-I-I-L-S-Q-E-P-L-S-A-D-L-E-E-D-E-E-E-P-E-L-L-D


### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-A-G-I-H-P-E-Y-K-A-V-N-A-T-C-S-C-G-N-S-F-V-F-N-S-T-L-D-K-D-S-I-H-L-D-V-C-D-K-C-H-P-F-Y-T-G-K-Q-R-I-V-D-T-G-G-R-V-D-R-F-N-K-R-F-G-A-L-S-S-G-K-K


### FUNCTION This regulatory protein, when combined with SAM  represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-A-D-W-N-G-E-Y-I-S-P-Y-A-E-H-G-K-K-S-E-Q-V-K-K-I-T-V-S-I-P-L-K-V-L-K-V-L-T-D-E-R-T-R-R-Q-I-N-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-Y-T-G-Q-P-L-P-T-D-E-D-L-R-K-D-R-P-D-D-I-P-T-E-A-K-E-L-M-T-A-M-G-I-E-F-E-A-Y-D-D


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-A-G-M-I-E-R-Y-T-G-S-I-T-E-A-G-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-V-L-M-N-V-E-A-D-Q-A-V-I-D-E-L-E-T-A-F-R-Y-N-D-A-V-L-R-N-M-I-M-R-T-K-A-A-I-T-E-P-S-I-M-L-K-Q-K-E-E-R-A-P-R-R-E-A-E-A-K-E-F-A-A-E


### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-T-N-R-M-E-L-S-G-T-V-V-K-D-P-I-R-S-Q-S-P-A-G-I-S-H-C-R-F-W-L-E-H-R-S-V-V-V-E-A-D-L-P-R-Q-V-F-C-R-M-P-V-V-V-S-G-K-G-S-Q-D-I-T-Q-Q-I-V-L-G-S-N-I-K-V-S-G-F-V-A-Y-Q-T-G-R-N-G-V-G-K-L-V-L-H-A-D-D-I-I-H-I


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-F-F-R-R-R-K-F-C-R-F-T-A-E-G-V-Q-E-I-D-Y-K-D-V-A-T-L-K-N-Y-I-T-E-A-G-K-I-V-P-S-R-I-T-G-T-S-A-K-Y-Q-R-Q-L-A-R-A-I-K-R-S-R-Y-L-A-L-L-P-Y-T-D-K-H-Q


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-D-K-I-G-N-L-G-S-L-G-D-T-V-N-V-K-S-G-Y-A-R-N-F-L-I-P-Q-G-K-A-V-M-A-T-K-G-N-V-E-M-F-E-A-R-R-A-E-L-E-A-K-V-A-E-Q-L-A-S-A-E-A-R-A-E-K-V-N-A-L-E-A-V-V-I-A-S-K-A-G-D-E-G-K-L-F-G-S-I-G-T-R-D-I-A-D-A-I-T-A-A-G-V-E-V-V-K-S-E-V-R-L-P-E-G-A-L-R-T-T-G-E-F-E-I-S-V-Q-L-H-S-E-V-F-A-T-V-K-L-Q-V-V-A-E


### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-N-K-E-T-K-L-Q-V-E-A-I-K-N-G-T-V-I-D-H-I-P-A-Q-V-G-I-K-V-L-K-L-F-D-M-H-N-S-S-Q-R-V-T-I-G-L-N-L-P-S-S-A-L-G-N-K-D-L-L-K-I-E-N-V-F-I-N-E-E-Q-A-S-K-L-A-L-Y-A-P-H-A-T-V-N-Q-I-E-D-Y-Q-V-V-K-K-L-A-L-E-L-P-E-F-V-S-D-V-F-E-C-P-N-S-N-C-I-T-H-N-E-P-V-A-S-N-F-R-V-F-E-K-K-G-D-V-R-L-K-C-K-Y-C-E-K-V-F-S-R-E-I-V-T-E-R


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-R-T-I-M-A-F-D-F-G-T-K-S-I-G-S-A-I-G-Q-E-I-T-G-T-A-S-P-L-K-A-F-K-A-N-D-G-I-P-N-W-D-E-I-E-K-Q-I-K-E-W-Q-P-N-L-L-V-V-G-L-P-T-D-L-H-G-K-A-L-E-T-I-T-P-R-A-K-K-F-A-Q-R-L-Q-G-R-F-A-L-P-V-E-L-H-D-E-R-L-S-T-T-E-A-R-S-E-L-F-S-M-G-G-Y-K-A-L-S-K-G-N-V-D-C-Q-S-A-V-I-I-L-E-S-W-F-E-A-Q-W-G


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-V-G-L-G-T-D-I-A-E-I-E-R-V-E-K-A-L-A-R-S-G-V-A-F-A-E-R-I-L-S-V-Q-E-M-E-T-F-V-S-L-K-Q-Q-G-R-F-L-A-K-R-F-A-A-K-E-A-A-S-K-A-L-G-T-G-I-A-H-G-V-S-F-Q-D-F-T-I-K-N-D-D-N-G-K-P-Y-L-Q-L-A-G-R-A-A-E-L-A-H-Q-M-G-V-C-H-T-H-L-S-L-S-D-E-R-H-Y-A-V-A-T-V-I-F-E-S


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-L-F-I-L-V-L-T-L-L-F-G-W-L-Q-Y-T-L-W-F-G-K-N-G-V-S-D-Y-Y-T-I-E-S-D-I-E-A-Q-Q-L-V-N-T-K-L-Q-A-R-N-S-E-M-Y-A-E-I-D-D-L-K-Q-G-L-D-A-I-E-E-R-A-R-H-E-L-G-M-L-K-E-G-E-T-F-Y-R-I-V-G-E-E-N-Q


### FUNCTION Modulates RecA activity ### SEQUENCE -M-H-H-R-F-T-P-P-M-M-N-C-K-D-T-A-I-Q-L-L-S-R-R-D-H-G-Q-Y-E-L-K-Q-K-L-T-L-K-G-Y-A-S-Q-D-I-E-S-A-M-H-F-C-L-E-H-G-Y-L-D-D-L-R-Y-A-K-S-Q-I-R-Q-H-V-G-K-G-H-G-E-R-R-I-R-Q-E-L-S-L-K-Q-V-S-D-S-V-V-E-N-A-F-A-E-E-P-Q-D-W-F-E-L-A-K-S-V-A-M-K-K-F-N-G-V-K-A-K-E-Q-K-E-Y-A-K-Q-V-R-F-L-Q-Y-R-G-F-S-F-E-Q-I-R-Y-A-L-N-D-K-A


### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-M-I-G-D-E-V-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-V-N-A-P-K-D-V-S-V-H-R-E-E-I-Y-M-R-I-Q-A-E-K-G-N-V-T-P-G-N-Y


### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-T-V-D-H-T-R-M-H-A-P-A-V-R-V-A-K-T-M-Q-T-P-K-G-D-T-I-T-V-F-D-L-R-F-T-A-P-N-K-D-I-L-S-E-K-G-I-H-T-L-E-H-L-Y-A-G-F-M-R-K-H-L-N-G-A-S-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-A-P-S-E-Q-D-V-A-S-A-W-T-A-S-M-E-D-V-L-K-V-E-S-Q-N-K-I-P-E-L-N-E-Y-Q-C-G-T-A-A-M-H-S-L-D-E-A-K-Q-I-A-Q-N-I-L-A-A-G-I-S-V-N-K-N-D-E-L-A-L-P-E-A-M-L-K-E-L-K-V-D


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-M-K-G-K-E-T-M-S-D-E-R-I-V-V-G-K-F-G-S-T-Y-G-I-R-G-W-L-K-V-F-S-Y-T-D-N-A-E-S-L-F-D-Y-S-P-W-Y-V-N-Q-K-G-E-W-V-E-F-K-V-E-S-W-K-R-H-N-K-G-M-V-A-K-L-E-G-L-D-V-R-E-D-A-H-L-L-T-N-L-E-I-A-I-D-P-A-V-L-P-E-L-S-E-D-E-F-Y-W-R-E-L-F-G-M-Q-V-V-T-T-N-G-Y-D-L-G-V-V-T-D-M-L-E-T-G-S-N-D-V-L-V-V-K-A-N-L-K-D-A-F-G-Q-K-E-R-L-I-P-F-L-E-E-Q-V-I-I-K-V-D-R-E-A-Q-R-I-E-V-D-W-D-P-G-F


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-N-I-I-K-A-L-E-Q-E-Q-M-K-Q-D-L-P-K-F-A-P-G-D-T-V-V-V-Q-V-K-V-K-E-G-N-R-E-R-L-Q-A-Y-E-G-V-V-I-A-I-R-N-R-G-L-H-S-A-F-T-V-R-K-I-S-N-G-E-G-V-E-R-T-F-Q-T-H-S-P-V-V-D-S-I-E-V-K-R-R-G-A-V-R-R-A-K-L-Y-Y-L-R-E-R-S-G-K-S-A-R-I-K-E-K-L-A-K-K


### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-T-K-I-T-I-V-K-C-P-Q-C-G-T-D-V-E-W-G-E-Q-S-P-H-R-P-F-C-S-K-K-C-Q-M-I-D-F-G-E-W-A-D-E-E-N-A-I-P-G-A-P-D-M-S-D-S-D-G-W-S-E-E-Q-Y


### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-D-I-N-L-P-L-S-F-S-D-A-A-A-T-R-V-K-M-L-I-A-E-E-E-N-P-A-L-K-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-S-V-N-E-G-D-T-T-I-E-N-S-G-V-T-L-V-V-D-P-M-S-L-Q-Y-L-I-G-G-V-V-D-Y-T-E-G-L-E-G-S-R-F-F-V-N-N-P-N-A-T-T-T-C-G-C-G-A-S-F-S-V


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-G-L-E-R-Q-L-T-E-M-L-E-S-A-V-V-A-S-G-Y-E-L-V-G-L-E-F-I-R-A-G-E-H-S-T-L-R-I-Y-I-D-H-E-N-G-I-T-V-E-D-C-A-E-V-S-H-Q-V-S-A-V-L-D-V-E-D-P-I-S-V-A-Y-S-L-E-V-S-S-P-G-L-D-R-P-L-F-K-P-A-H-Y-E-Q-F-I-G-Q-E-V-N-V-V-L-K-M-A-V-A-N-R-R-K-W-K-G-E-I-H-S-V-D-G-E-A-I-T-L-T-V-D-G-Q-Q-E-E-F-A-L-S-N-I-S-K-A-N-L-I-P-K-F


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-K-D-F-S-R-T-Q-R-V-S-Q-Q-L-Q-K-E-L-A-M-I-L-Q-R-E-V-R-D-S-R-L-G-M-V-T-I-S-D-V-E-V-S-R-D-L-A-Y-A-K-V-F-V-T-F-L-C-V-G-E-Q-T-P-E-S-C-L-A-A-L-R-E-H-E-V-H-I-R-M-M-L-G-K-R-I-R-L-R-L-T-P-E-V-R-F-Y-Y-D-N-T-L-V-E-G-M-R-M-S-N-L-V-T-E-V-V-N-K-D-K-I-K-Q-K-D-A-G-R-E-D-E-E


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-N-A-E-T-K-A-A-I-V-A-D-Y-A-R-G-E-G-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-S-I-N-H-L-Q-G-H-F-Q-A-H-K-G-D-H-H-S-R-R-G-L-L-R-M-V-S-R-R-R-K-L-L-D-Y-L-K-G-K-D-L-A-R-Y-Q-D-L-I-K-R-L-G-L-R-R


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-D-I-K-K-D-A-Q-E-R-M-E-K-S-V-E-A-L-K-N-S-L-S-K-V-R-T-G-R-A-H-P-S-L-L-S-G-I-S-V-D-Y-Y-G-A-A-T-P-L-T-Q-V-A-N-V-I-A-E-D-A-R-T-L-A-I-T-V-F-D-K-E-L-T-Q-K-V-E-K-A-I-M-M-S-D-L-G-L-N-P-M-S-A-G-T-V-I-R-V-P-L-P-P-L-T-E-E-R-R-K-D-L-V-K-I-V-R-G-E-A-E-G-G-R-V-A-V-R-N-I-R-R-D-A-N-S-D-L-K-A-L-L-K-E-K-E-I-S-E-D-E-D-R-K-A-Q-D-E-I-Q-K-L-T-D-A-A-V-K-K-I-D-D-V-L-A-A-K-E-K-E-L-M-E-V


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-T-N-T-I-A-Q-I-Q-A-S-I-K-S-I-P-D-Y-P-K-P-G-I-L-F-R-D-V-T-S-L-L-E-D-A-Q-A-Y-Q-A-T-I-Q-L-L-V-D-K-Y-K-D-M-G-F-T-K-V-V-G-T-E-A-R-G-F-L-F-G-A-P-L-A-L-Q-L-G-V-G-F-V-P-V-R-K-P-G-K-L-P-R-N-T-I-A-Q-S-Y-E-L-E-Y-G-V-D-T-L-E-I-H-T-D-A-I-V-E-G-D-K-V-L-V-V-D-D-L-L-A-T-G-G-T-I-E-A-T-T-K-L-I-R-Q-L-G-G-V-V-E-H-A-A-F-V-I-N-L-P-E-I-G-G-D-K-R-L-E-G-L-G-L-N-V-Y-S-I-C-E-F-E-G-H


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-G-G-M-G-N-L-M-K-Q-A-Q-Q-M-Q-E-R-M-Q-K-L-Q-E-E-I-A-N-M-E-V-V-G-E-S-G-A-G-L-V-K-V-T-I-T-G-S-H-S-V-R-R-V-N-I-D-E-S-L-M-E-D-D-K-E-M-L-E-D-L-I-A-A-A-F-N-D-A-A-R-R-V-E-E-T-Q-K-E-K-M-A-A-I-T-G-G-M-Q-L-P-P-G-M-K-M-P-F


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-R-T-S-H-M-L-E-Q-L-M-E-A-L-R-C-L-P-G-V-G-P-K-S-A-Q-R-M-A-F-H-L-L-Q-R-D-R-K-G-G-L-Q-L-A-D-A-L-S-H-A-M-T-E-I-G-H-C-N-E-C-R-T-F-T-E-E-D-V-C-H-I-C-N-N-P-K-R-Q-E-N-G-L-L-C-V-V-E-S-P-A-D-I-A-A-V-E-A-T-G-Q-F-S-G-R-Y-F-V-L-M-G-H-L-S-P-L-D-G-I-G-P-S-D-I-G-L-D-V-L-D-Y-R-L-R-R-G-D-I-K-E-V-I-L-A-T-N-P-T-V-E-G-E-A-T-A-H-Y-I-A-E-L-C-R-E-H-K-V-D-A-S-R-I-A-H-G-V-P-V-G-G-E-L-E-L-V-D-G-T-T-L-S-H-S-L-L-G-R-H-K-L-N


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-K-N-F-E-W-I-T-P-D-S-D-L-L-E-K-E-I-T-Q-I-Q-P-P-K-K-Y-N-V-V-L-N-N-D-D-Y-T-P-M-D-F-V-I-D-V-L-E-R-F-F-S-H-D-L-D-K-A-T-Q-I-M-L-K-V-H-Y-E-G-K-A-I-C-G-T-Y-S-A-E-I-A-E-T-K-V-A-Q-V-T-M-Y-S-R-E-N-E-H-P-L-L-C-T-M-E-Q-A


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-D-V-I-E-M-Q-G-T-V-L-D-T-L-P-N-T-M-F-R-V-E-L-E-N-G-H-V-V-T-A-H-I-S-G-K-M-R-K-N-Y-I-R-I-L-T-G-D-K-V-T-V-E-M-T-P-Y-D-L-S-K-G-R-I-V-F-R-A-R


### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-N-L-F-A-S-L-N-Q-F-S-K-N-R-I-S-W-L-L-L-L-L-F-V-V-F-F-E-G-A-A-L-F-F-Q-H-V-M-M-L-S-P-C-V-M-C-I-Y-E-R-V-A-M-L-G-V-G-G-A-A-L-F-G-L-I-A-P-N-N-P-L-V-R-W-L-G-L-A-A-W-G-A-S-A-Y-K-G-L-A-L-S-L-Q-H-V-D-Y-Q-F-N-P-S-P-F-A-T-C-D-L-F-V-T-F-P-D-W-A-P-L-N-Q-W-A-P-W-M-F-E-A-Y-G-D-C-S-K-I-V-W-Q-F-M-T-L-S-M-P-Q-W-L-V-I-I-F-A-G-N-L-V-A-L-A-F-I-V-I-A-Q-F-F-K-S-K


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-D-L-A-E-N-L-F-E-K-L-G-F-S-K-R-D-A-K-D-T-V-E-V-F-F-E-E-I-R-K-A-L-E-N-G-E-Q-V-K-L-S-G-F-G-N-F-D-L-R-D-K-N-E-R-P-G-R-N-P-K-T-G-E-D-I-P-I-T-A-R-R-V-V-T-F-R-P-G-Q-K-L-K-A-R-V-E-N-L-K


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-Q-A-R-A-R-H-K-K-V-L-K-Q-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-T-K-A-G-Q-Y-A-Y-R-D-R-R-A-K-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-S-R-Q-N-G-L-S-Y-S-R-F-I-N-G-L-K-K-A-S-I-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-A-A-F-A-V-L-V-E-K-A-K-A-A-L


### FUNCTION Required for spatial organization of the terminus region of the chromosome  during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-Q-L-E-N-L-E-C-G-W-K-W-Q-Y-L-I-N-K-W-K-D-G-E-T-I-T-K-Y-I-D-S-S-E-A-D-H-A-V-S-E-L-R-K-L-E-H-E-P-T-K-V-L-E-W-I-D-L-H-M-A-E-E-L-D-K-K-L-K-Q-A-I-R-A-K-R-K-R-H-F-N-A-E-Q-I-H-T-K-K-K-S-I-D-L-D-Y-R-V-W-E-K-L-S-T-R-A-N-E-L-G-C-T-L-S-D-A-I-E-Y-L-L-S-E-A-S-R-S-E-K-A-S-A-A-V-S-T-L-K-E-D-L-S-K-L-L-S-D


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-K-F-E-A-V-V-R-T-E-L-G-K-G-A-S-R-R-L-R-L-A-G-Q-F-P-A-V-V-Y-G-G-E-A-A-P-V-A-V-A-L-N-H-D-D-I-V-N-Q-M-D-K-P-E-F-Y-E-A-I-T-L-V-I-G-G-E-E-V-K-V-K-P-Q-D-V-Q-R-H-A-F-K-P-K-V-E-H-M-D-F-I-R-I


### FUNCTION Participates in the translocation of lipoproteins from the inner membrane to the outer membrane Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate ### SEQUENCE -M-K-K-W-L-V-V-F-F-L-S-A-S-A-L-A-N-P-Q-Q-E-L-N-Q-R-L-G-M-N-D-G-F-S-A-N-F-N-Q-T-V-T-S-P-E-G-E-V-V-M-E-G-E-G-S-V-D-I-A-R-P-S-L-F-R-W-S-T-S-L-P-D-E-N-L-L-V-S-D-G-K-T-L-W-Y-Y-S-P-F-I-E-Q-V-S-I-Y-W-Q-E-Q-A-V-Q-Q-T-P-F-V-L-L-T-R-N-Q-S-S-D-W-E-N-Y-Q-I-T-Q-D-G-N-V-F-T-L-V-P-K-A-A-D-S-T-Q-G-Q-F-Q-I-D-I-D-A-K-G-I-V-H-G-F-N-V-I-E-Q-D-G-Q-K-G-I-F-K-F-T-D-M-K-L-G-K-P-A-A-A-R-F-T-F-N-I-P-E-G-V-E-V-D-D-Q-R-N


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-R-L-C-A-E-Q-T-H-L-S-A-K-E-I-E-D-A-V-K-D-I-L-E-H-M-A-S-T-L-E-S-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-E-P-R-V-G-R-N-P-K-T-G-D-K-V-E-L-E-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-E-R-V-H-I-G


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-N-L-E-E-R-V-K-K-I-I-V-E-Q-L-G-V-D-E-S-E-V-K-N-E-A-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-A-A-I-D-Y-V-T-A-N-A-Q


### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-E-N-Y-Q-L-V-L-A-S-T-S-P-F-R-Q-Q-L-L-E-K-L-A-I-P-F-S-T-L-S-P-N-C-D-E-T-P-L-E-D-E-S-P-Q-Q-L-V-L-R-L-A-E-S-K-A-Q-S-C-Q-I-N-Q-P-S-L-V-I-G-S-D-Q-V-C-V-I-N-G-N-I-V-G-K-P-H-N-R-Q-N-A-I-A-Q-L-T-A-Q-S-G-Q-S-I-V-F-Y-T-G-L-A-V-Y-N-S-E-T-G-E-T-R-S-C-I-D-E-F-K-V-H-F-R-P-L-T-Q-A-Q-I-E-R-Y-V-D-K-E-Q-P-F-Y-C-A-G-S-F-K-S-E-G-L-G-I-A-L-F-E-K-L-E-G-K-D-P-N-T-L-V-G-L-P-L-I-D-L-I-D-L-L-A-Q-Q-G-M-Q-V-L-G


### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-K-Q-I-L-D-F-I-P-L-I-I-F-F-A-L-Y-K-M-Y-D-I-Y-V-A-T-G-A-L-I-A-A-T-A-I-Q-I-V-V-T-Y-A-L-Y-K-K-V-E-K-M-Q-L-I-T-F-L-M-V-A-I-F-G-G-M-T-I-F-L-H-D-D-N-F-I-K-W-K-V-T-I-V-Y-A-V-F-A-I-G-L-T-V-S-H-V-M-G-K-S-A-I-K-G-M-L-G-K-E-I-T-L-P-E-S-V-W-A-N-I-N-W-A-W-V-G-F-F-T-F-C-A-G-L-N-I-Y-V-A-Y-Q-L-P-L-D-V-W-V-N-F-K-V-F-G-L-L-A-A-T-L-V-F-T-V-L-T-G-G-Y-I-Y-K-H-L-P-K-E-Q-N-G-Q-S-S-D-V-P-T-D-E


### FUNCTION Phosphorelay protein which receives a sensory signal from a sensor kinase and transmit it to LuxO At low cell density, a phosphoryl group is transferred from the sensor kinase, probably on His-56 and this phosphoryl group is further transferred to LuxO ### SEQUENCE -M-E-L-L-N-Q-K-K-I-A-S-L-T-E-E-I-G-A-D-N-V-P-V-L-L-E-I-F-L-S-E-L-E-S-Y-L-K-V-L-C-D-A-T-Y-S-D-K-L-V-Y-L-K-D-I-S-H-A-L-K-S-S-A-A-S-F-G-A-D-A-L-C-H-F-A-V-E-I-D-T-R-A-K-E-G-D-A-L-D-E-T-Q-D-V-V-A-M-I-D-R-L-H-Q-T-Q-Q-A-Y-L-S-W-Q-A-N-G-F


### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-T-E-Y-I-L-L-L-I-G-T-V-L-V-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-L-E-T-A-I-G-M-G-L-A-T-T-F-V-L-T-M-A-S-V-C-A-Y-L-V-E-S-Y-I-L-E-P-L-H-I-E-Y-L-R-T-M-S-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-V-V-H-K-T-S-P-T-L-Y-R-L-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-I-N-E-N-H-S-F-V-E-S-I-I-Y-G-F-G-A-A-V-G-F-S-L-V-L-I-L-F-A-S-M-R-E-R-I-S-A-A-D-V-P-A-P-F-K-G-A-S-I-A-M-I-T-A-G-L-M-S-L-A-F-M-G-F-T-G-L-V-K


### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-L-E-F-F-R-P-Q-K-K-T-S-A-S-L-A-K-E-R-L-Q-I-I-V-A-E-R-R-S-Q-N-D-P-A-P-S-Y-L-P-Q-L-K-E-D-I-L-K-V-I-S-K-Y-V-A-I-D-P-A-M-V-D-L-T-F-E-H-K-D-D-D-I-S-V-L-E-L-N-V-K-L-P-D-E-E-K


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-Q-Q-I-K-L-L-V-G-L-A-N-P-G-P-E-Y-A-K-T-R-H-N-A-G-A-W-V-V-E-E-L-A-R-V-H-N-I-T-L-K-N-E-A-K-F-Y-G-L-T-G-R-I-V-M-N-G-Q-E-L-R-L-L-I-P-T-T-F-M-N-L-S-G-K-A-I-A-A-L-A-K-F-Y-Q-I-Q-P-E-E-I-M-V-A-H-D-E-L-D-L-P-P-G-I-A-K-F-K-K-G-G-G-H-G-G-H-N-G-L-R-D-T-I-S-K-L-G-N-N-K-E-F-Y-R-L-R-I-G-I-G-H-P-G-H-K-D-K-V-A-G-F-V-L-G-K-A-P-A-S-E-Q-S-L-L-D-A-T-V-D-E-S-V-R-C-L-D-I-L-I-K-D-G-L-S-K-A-Q-N-R-L-H-T-F-K-A-E


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-A-I-E-L-D-L-Q-L-A-V-E-D-Q-N-G-L-P-S-A-Q-D-F-Q-T-W-L-D-K-T-I-P-P-F-Q-P-Q-A-E-V-T-I-R-I-V-D-S-Q-E-S-H-Q-L-N-H-D-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-A-P-P-G-M-E-M-D-L-L-G-D-L-V-I-C-R-Q-V-V-E-Q-E-A-I-E-Q-D-K-P-L-M-A-H-W-A-H-M-V-V-H-G-S-L-H-L-L-G-Y-D-H-I-E-D-D-E-A-E-E-M-E-S-L-E-T-E-I-M-Q-G-M-G-F-T-D-P-Y-L-A-E-K-E


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-K-I-Q-L-I-A-V-G-T-K-M-P-K-W-V-E-E-G-F-Q-E-Y-R-R-R-F-P-H-D-M-P-L-E-L-I-E-I-T-A-G-K-R-G-K-N-A-D-I-A-R-I-L-Q-K-E-G-E-A-M-L-A-A-I-P-K-G-N-R-I-V-T-L-D-I-P-G-K-K-W-D-T-P-E-L-A-Q-Q-L-E-A-W-K-L-D-G-R-D-V-S-I-L-I-G-G-P-E-G-L-A-P-A-C-K-A-A-A-E-Q-S-W-S-L-S-A-L-T-L-P-H-P-L-V-R-I-V-M-A-E-S-L-Y-R-A-W-S-I-T-T-N-H-P-Y-H-R-E


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-T-K-K-P-E-N-M-S-F-E-A-T-I-E-E-L-D-N-L-V-D-Q-L-E-N-G-D-L-A-L-D-D-A-L-K-K-F-E-R-G-I-A-L-A-R-A-S-Q-A-K-L-T-E-A-E-Q-R-V-S-I-L-L-S-D-S-D-D-A-P-L-S-D-F-S-T-L-A-E


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-G-A-S-V-K-P-A-A-R-R-N-A-R-Q-F-A-L-Q-A-I-Y-S-W-Q-I-T-K-E-N-V-A-T-I-E-A-Q-F-L-A-G-E-K-Y-D-E-E-E-H-R-A-A-E-P-A-L-A-A-P-E-T-D-V-A-Y-F-R-D-L-L-T-G-V-V-L-S-H-T-E-L-D-S-K-I-R-P-Y-V-S-R-P-M-Q-D-L-D-M-M-E-L-A-L-L-R-L-A-M-Y-E-M-T-R-R-E-D-V-P-Y-K-V-V-I-N-E-A-I-E-L-A-K-V-F-A-A-E-D-S-H-K-F-V-N-G-V-L-D-K-A-A-P-H-V-R-K-K


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-S-E-N-D-T-K-V-I-D-S-R-L-V-A-D-G-H-Q-V-R-R-R-R-Q-C-L-A-C-N-E-R-F-T-T-F-E-T-A-E-L-L-M-P-K-V-I-K-S-N-G-N-R-E-P-F-N-E-D-K-M-V-G-G-I-Q-R-A-L-E-K-R-P-V-S-A-D-A-I-E-L-A-I-S-M-I-K-S-K-L-R-A-T-G-E-R-E-V-P-S-K-M-I-G-N-L-V-M-E-Q-L-K-H-L-D-K-V-A-Y-I-R-F-A-S-V-Y-R-S-F-E-D-I-R-E-F-G-E-E-I-A-R-L-E-D


### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-S-E-V-T-N-N-P-T-H-N-R-L-L-A-K-L-R-A-M-G-P-Y-L-R-D-P-Q-S-K-E-G-L-Y-Y-F-D-C-L-S-V-C-I-D-D-R-K-S-P-E-L-R-E-F-W-G-W-W-M-E-L-E-A-T-E-G-G-F-T-A-N-Y-H-I-G-K-Y-D-V-E-G-N-W-L-D-L-A-I-P-K-N-A-L-E-E-V-N-K-T-Q-N-C-F-H-L-K-L-V-K-T-L-E-E-N-F-Q-L-S-V-A-Y-H-E-Q-S-V-E-F-V


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-N-E-E-N-K-I-N-E-E-A-L-K-Q-Q-D-A-A-E-V-E-V-E-A-V-G-T-D-A-D-I-E-W-N-E-E-A-D-E-S-A-V-K-I-A-E-L-E-A-A-L-L-A-S-E-A-R-V-K-E-Q-Q-D-S-V-L-R-A-K-A-E-V-E-N-M-R-R-R-T-E-Q-E-I-D-K-A-R-K-Y-A-L-N-R-F-A-E-E-L-L-P-V-I-D-N-L-E-R-A-I-Q-A-A-D-A-E-S-E-A-V-K-P-L-L-E-G-V-E-L-T-H-K-T-F-V-D-V-V-S-K-F-G-L-K-E-I-N-P-E-G-Q-P-F-N-P-E-W-H-Q-A-M-S-I-Q-E-S-P-D-H-E-S-N-T-V-M-F-V-M-Q-K-G-Y-E-L-N-G-R-V-I-R-P-A-M-V-M-V-A-K


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-N-S-K-P-K-A-G-S-N-T-I-A-L-N-K-K-A-R-H-E-Y-F-I-E-D-E-I-E-A-G-M-E-L-Q-G-W-E-V-K-A-L-R-Q-G-K-A-N-I-S-E-S-Y-V-F-M-R-D-G-E-A-F-V-S-G-M-T-I-T-P-L-N-Q-A-S-T-H-V-V-A-N-P-T-R-V-R-K-L-L-M-S-R-R-E-L-D-N-L-L-G-R-I-N-R-E-G-M-T-L-A-A-L-S-L-Y-W-A-R-S-W-V-K-I-K-I-G-V-A-K-G-K-K-L-H-D-K-R-D-D-I-K-D-R-D-W-Q-R-Q-K-A-R-V-M-K-S-S-L-R


### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-H-F-E-L-F-G-L-P-P-Q-F-S-L-D-G-S-L-L-S-S-Q-F-R-E-L-Q-K-R-F-H-P-D-N-F-A-T-A-S-E-R-D-R-L-L-A-V-Q-K-A-A-Q-I-N-D-A-Y-Q-V-L-K-N-P-I-S-R-A-E-Y-L-L-S-Q-N-G-L-E-I-R-G-E-Q-Q-T-M-Q-D-P-M-F-L-M-E-Q-M-E-L-R-E-E-L-E-E-I-P-H-G-S-D-A-E-S-A-L-A-A-F-D-A-R-V-S-K-M-Y-K-Q-H-L-A-S-I-E-Q-E-L-N-D-A-Q-W-P-Q-A-A-D-R-V-R-K-L-K-F-I-A-K-L-K-N-E-I-E-L-V-E-E-K-L-F-G


### FUNCTION Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins ### SEQUENCE -M-K-L-T-S-K-G-R-Y-A-V-T-A-M-L-D-V-A-L-H-S-Q-K-S-P-V-P-L-A-D-I-S-E-R-Q-G-I-S-L-S-Y-L-E-Q-L-F-S-K-L-R-K-A-G-L-V-A-S-V-R-G-P-G-G-G-Y-R-L-G-A-D-A-F-T-I-S-I-G-T-V-I-A-A-V-D-E-S-V-D-A-T-K-C-Q-G-K-G-D-C-Q-G-G-T-R-C-L-T-H-T-L-W-R-D-L-S-S-R-I-T-D-F-L-N-N-I-T-L-G-E-L-M-S-D-N-E-V-I-E-I-S-D-R-Q-D-I-D-L-A-V-N-H-G-L-A-N-K-T-I-N-T-A-P-I-G-V-N-F-R-S


### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-S-Q-Q-P-E-Y-T-D-W-Q-Q-I-V-D-L-V-K-H-S-V-E-Q-K-Q-H-D-M-L-L-T-M-L-M-T-P-D-E-R-E-A-L-V-S-R-V-N-I-V-R-E-L-L-K-G-E-L-S-Q-R-Q-I-S-Q-M-L-G-V-G-I-A-T-I-T-R-G-S-N-E-L-K-L-K-S-D-E-D-K-A-R-L-N-Q-L-L-E-G-T-K-K-G-G


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-N-K-S-A-K-K-R-A-I-Q-A-E-K-R-R-Q-H-N-A-S-R-R-S-M-M-R-T-Y-M-K-K-T-V-A-A-I-A-A-G-D-K-E-A-A-T-A-A-F-A-V-V-T-P-I-L-D-R-M-A-T-K-G-L-I-H-K-N-K-A-A-R-H-K-S-R-F-A-A-Q-I-K-A-L


### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-G-D-G-Y-R-L-N-V-G-I-V-I-C-N-N-H-G-Q-V-F-W-A-K-R-Y-G-Q-H-S-W-Q-F-P-Q-G-G-I-D-D-G-E-T-P-E-Q-A-M-F-R-E-L-Y-E-E-V-G-L-T-H-K-D-V-K-I-I-A-S-S-R-H-W-L-R-Y-K-L-P-K-R-L-V-R-W-D-S-K-P-V-C-I-G-Q-K-Q-K-W-F-L-L-R-L-E-C-D-E-S-K-I-N-M-Q-K-G-S-S-P-E-F-D-G-W-R-W-V-S-Y-W-Y-P-V-R-Q-V-V-S-F-K-R-D-V-Y-R-R-A-M-K-E-F-A-S-L-A-M-P-F-R-E-R-K-L-K-G-K-K-V-K-R-R-G


### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-Q-G-I-Q-I-T-K-A-A-N-D-D-L-L-N-S-I-W-L-L-D-S-E-K-N-E-A-R-C-V-A-A-V-S-G-Y-E-A-D-Q-I-V-A-I-N-E-L-G-E-F-E-S-R-E-V-A-I-E-A-A-P-R-I-E-G-G-Q-H-L-N-V-N-V-L-K-R-E-T-L-E-D-A-V-A-H-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-A-R-T-F-T-E-S-L


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-V-A-K-P-E-T-V-K-R-D-W-Y-V-V-D-A-E-G-K-T-L-G-R-L-A-S-E-I-A-S-R-L-R-G-K-H-K-A-E-Y-T-P-H-V-D-T-G-D-Y-I-I-V-I-N-A-E-K-V-T-V-T-G-N-K-A-A-A-K-T-Y-Y-R-H-T-E-F-P-G-G-I-K-S-I-T-F-D-K-L-I-V-R-K-P-E-M-V-I-E-L-A-V-K-G-M-L-P-R-G-P-L-G-R-A-M-Y-R-K-L-K-V-Y-A-G-A-E-H-N-H-V-A-Q-Q-P-K-V-L-D-I


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-S-E-G-Q-T-L-R-L-E-K-L-D-V-E-T-G-A-T-V-E-F-D-K-V-L-L-V-A-N-G-E-D-I-K-V-G-A-P-L-V-E-G-G-K-V-V-A-E-V-V-Q-H-G-R-G-D-K-V-K-I-V-K-F-R-R-R-K-H-S-R-K-Q-Q-G-H-R-Q-W-F-T-E-V-K-I-T-G-I-N-A


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-R-P-S-E-K-Q-D-N-L-V-R-A-F-K-A-L-L-K-E-E-R-F-G-S-Q-G-E-I-V-E-A-L-K-Q-E-G-F-E-N-I-N-Q-S-K-V-S-R-M-L-T-K-F-G-A-V-R-T-R-N-A-K-M-E-M-V-Y-C-L-P-T-E-L-G-V-P-T-V-S-S-S-L-R-E-L-V-L-D-V-D-H-N-Q-A-L-V-V-I-H-T-G-P-G-A-A-Q-L-I-A-R-M-L-D-S-L-G-K-S-E-G-I-L-G-V-V-A-G-D-D-T-I-F-I-T-P-T-L-T-I-T-T-E-Q-L-F-K-S-V-C-E-L-F-E-Y-A-G


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-Q-P-T-R-A-R-K-R-V-R-K-Q-V-A-D-G-V-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-A-W-A-T-A-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-R-C-A-E-M-A-K-E-Y-G-L-K-N-L-E-V-M-V-K-G-P-G-P-G-R-E-S-T-V-R-A-L-N-A-A-G-F-R-I-T-N-I-V-D-A-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-A-V-I-A-L-T-A-I-Y-G-I-G-K-T-R-S-K-A-I-L-A-D-V-G-I-A-E-D-V-K-I-S-E-L-T-E-E-Q-I-D-Q-L-R-D-G-V-A-K-Y-T-V-E-G-D-L-R-R-E-V-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-S-L-P-L-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-S-P-A-A-G-S-K-H-A-P-K-R-V-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-K-S-R-S-G-G-K-V-R-P-G-F-E-G-G-Q-M-P-L-K-Q-R-L-P-K-F-G-F-T-S-R-K-S-L-V-S-A-E-V-R-V-A-E-L-A-K-V-T-G-D-V-V-D-L-N-S-L-K-A-A-N-V-I-T-K-N-I-E-N-V-K-I-V-L-S-G-E-I-N-K-A-V-T-V-K-G-L-R-V-T-K-G-A-K-A-A-I-E-A-A-G-G-K-I-E-E


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-K-E-Q-Q-V-Q-A-N-D-L-Q-E-K-L-I-A-V-N-R-V-S-K-T-V-K-G-G-R-I-M-S-F-T-A-L-T-V-V-G-D-G-N-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-N-M-V-T-I-A-L-N-E-G-T-L-H-H-P-V-K-G-R-H-S-G-S-K-V-Y-M-Q-P-A-A-E-G-T-G-V-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-H-N-V-L-S-K-A-Y-G-S-T-N-P-I-N-I-V-R-A-T-I-D-A-L-V-D-V-K-S-P-E-M-V-A-A-K-R-G-L-T-V-E-A-I-S-E


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-A-S-R-I-R-R-A-T-R-A-R-R-K-I-A-E-L-G-A-T-R-L-V-V-H-R-T-P-R-H-V-Y-A-Q-V-I-A-A-N-G-S-E-V-I-A-A-A-S-T-V-E-K-A-I-R-E-Q-V-K-Y-T-G-N-I-E-A-A-K-A-V-G-K-A-V-A-E-R-A-L-E-K-G-V-S-T-V-A-F-D-R-S-G-F-Q-Y-H-G-R-V-A-A-L-A-D-S-A-R-E-A-G-L-K-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-A-I-P-A-G-V-E-V-K-L-N-G-Q-E-I-T-V-K-G-A-K-G-E-L-S-R-V-I-N-N-A-V-V-I-A-Q-E-E-N-K-L-T-F-G-P-R-E-G-V-A-N-A-W-A-Q-A-G-T-A-R-A-L-V-N-N-M-V-V-G-V-T-E-G-F-T-R-K-L-I-L-K-G-V-G-Y-R-A-A-I-K-G-N-A-V-G-L-T-L-G-F-S-H-P-V-E-H-E-L-P-A-G-I-K-A-E-C-P-S-Q-T-E-I-V-L-T-G-C-D-K-Q-L-I-G-Q-V-A-A-D-I-R-A-Y-R-A-P-E-P-Y-K-G-K-G-I-R-Y-A-D-E-N-V-R-S-K-E-A-K-K-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-S-D-M-L-T-R-I-R-N-G-Q-A-A-N-K-V-A-V-K-M-P-S-S-K-L-K-V-A-I-A-A-L-L-K-A-E-G-Y-I-V-D-F-A-V-E-G-E-A-K-P-E-L-E-V-T-L-K-Y-F-Q-A-K-P-V-I-E-Q-L-K-R-V-S-R-P-G-L-R-V-Y-K-K-K-D-D-L-P-S-V-M-G-G-L-G-V-A-V-V-S-T-S-K-G-L-M-S-D-R-A-A-R-K-A-G-L-G-G-E-I-I-C-Y-V-A


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-E-A-K-R-A-K-L-V-A-K-F-A-E-K-R-A-S-L-K-A-I-I-S-D-V-N-V-S-E-E-D-R-W-N-A-V-L-K-L-Q-T-L-P-R-D-S-S-A-S-R-Q-R-N-R-C-N-Q-T-G-R-P-H-G-Y-L-R-K-F-G-L-S-R-I-K-V-R-E-A-C-M-K-G-E-I-P-G-L-R-K-A-S-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-K-S-S-V-V-A-E-L-T-K-Q-F-G-Y-T-S-V-M-Q-V-P-R-I-E-K-I-T-L-N-M-G-V-G-D-A-I-N-D-K-K-L-L-E-N-A-A-A-D-M-A-T-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-V-A-G-F-K-I-R-E-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-D-F-M-E-R-L-I-S-I-A-L-P-R-V-R-D-F-R-G-V-N-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-F-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-S-A-G-T-D-E-E-G-R-A-L-L-A-A-F-N-F-P-F-R-K


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-N-D-E-V-I-V-L-A-G-K-D-K-G-K-K-G-K-V-T-K-V-L-A-T-G-K-V-I-V-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-L-G-I-Q-G-G-I-V-E-Q-E-A-A-I-D-V-S-N-V-A-I-F-N-A-A-T-G-K-A-D-R-I-G-F-R-F-E-D-G-Q-K-V-R-F-F-K-S-N-G-E-T-V-S-N


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-M-L-D-A-A-D-N-S-G-A-R-S-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-H-I-G-D-V-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-D-V-L-K-A-V-V-V-R-T-R-K-G-V-R-R-P-D-G-S-V-I-R-F-D-R-N-A-C-V-L-L-N-N-N-T-E-Q-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-G-D-K-F-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-D-K-I-R-T-Q-L-G-R-V-V-S-D-K-M-D-K-S-I-V-V-A-I-E-R-M-V-K-H-P-I-Y-G-K-F-V-K-R-T-T-K-V-H-A-H-D-E-N-N-E-C-G-I-G-D-T-V-E-I-R-E-C-R-P-L-S-K-T-K-S-W-T-L-V-K-V-V-E-K-A-K-I


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-V-H-T-G-R-N-R-G-L-A-K-G-T-E-V-S-F-G-S-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-H-I-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-E-V-R-Q-G-K-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-K-V-M-Y-E-V-D-G-V-P-E-E-L-A-R-E-A-F-R-L-A-A-R-K-L-P-F-K-T-T-F-V-T-K-Q-V-M


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-I-A-K-H-N-F-A-R-I-S-P-Q-K-A-R-L-V-A-D-L-I-R-G-K-S-V-D-Q-A-L-E-I-L-T-F-S-N-K-K-A-A-V-L-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-E-G-A-D-I-D-D-L-N-V-A-K-I-F-V-D-E-G-P-T-M-K-R-I-M-P-R-A-K-G-R-A-D-R-I-L-K-R-S-S-H-I-T-V-V-V-A-D-R


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-V-E-K-A-V-E-S-G-D-K-K-P-L-K-T-W-S-R-R-S-M-I-I-P-T-M-I-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-F-V-T-E-E-M-I-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-A-A-D-K-K-A-K-K-R


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-T-Q-E-R-L-L-K-V-L-R-A-P-H-I-S-E-K-A-T-M-A-A-E-K-A-N-T-I-V-F-K-V-A-K-D-A-T-K-K-E-I-K-A-A-V-E-Q-L-F-E-V-E-V-K-S-V-N-T-L-I-T-K-G-K-T-K-R-Q-G-L-R-Q-G-R-R-S-D-V-K-K-A-Y-V-T-L-K-E-G-Q-D-L-D-F-V-G-G-A-E


### FUNCTION One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA It is important during the early stages of 50S assembly It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-E-L-M-V-K-G-A-A-A-L-T-V-S-E-A-T-F-G-R-E-F-N-E-A-L-V-H-Q-V-V-V-A-Y-A-A-G-A-R-Q-G-T-R-A-Q-K-T-R-S-E-V-S-G-G-G-A-K-P-W-R-Q-K-G-T-G-R-A-R-A-G-T-I-R-S-P-L-W-R-T-G-G-V-T-F-A-A-K-P-Q-D-H-S-Q-K-V-N-K-K-M-Y-R-G-A-M-K-S-I-L-S-E-L-V-R-Q-E-R-L-I-V-V-D-N-F-S-V-E-A-P-K-T-K-E-L-V-A-K-L-K-E-L-E-L-N-D-V-L-I-V-T-G-E-V-D-E-N-L-F-L-A-A-R-N-L-Y-K-V-D-A-R-D-V-A-G-I-D-P-V-S-L-I-A-F-N-K-V-L-M-T-A-D-A-V-K-Q-V-E-E-M-L-A


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-R-I-R-I-R-L-K-A-F-D-Y-K-L-I-D-A-S-T-A-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-R-F-T-V-L-I-S-P-H-V-N-K-K-A-R-D-Q-Y-E-I-R-T-H-K-R-L-I-D-I-V-E-P-T-D-K-T-V-D-A-L-M-R-L-D-L-A-A-G-V-D-V-Q-I-S-L-G


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-D-A-V-E-K-V-G-N-R-F-D-L-V-L-I-A-A-R-R-A-R-Q-M-Q-T-G-G-K-D-S-L-V-P-E-E-N-D-K-P-T-V-I-A-L-R-E-I-E-E-G-L-I-T-K-E-V-L-D-A-R-E-R-Q-E-Q-Q-E-Q-E-A-A-E-L-A-A-V-S-S-I-A-R-N-R


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-K-T-K-M-I-T-R-E-G-Y-N-K-L-K-Q-E-L-D-Y-L-W-K-E-H-R-P-E-I-T-Q-K-V-S-W-A-A-S-L-G-D-R-S-E-N-A-D-Y-T-Y-N-K-R-L-L-R-Q-I-D-R-R-V-R-F-L-S-K-F-L-P-E-V-K-I-V-D-Y-A-P-Q-Q-E-G-K-V-F-F-G-A-W-V-E-I-E-N-E-A-G-E-V-M-K-F-R-I-V-G-P-E-E-I-Y-G-D-A-K-G-Y-I-S-I-D-S-P-M-A-R-A-L-L-K-K-E-V-D-D-E-V-Q-V-P-T-P-S-G-I-K-E-W-F-I-N-S-I-E-Y-D-K-G-Q


### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-S-N-I-T-I-T-E-A-A-Q-T-H-F-A-N-L-L-G-Q-Q-P-D-G-T-N-I-R-V-F-V-V-N-P-G-T-Q-N-A-E-C-G-V-S-Y-C-P-P-E-A-V-E-A-T-D-T-E-I-P-Y-Q-S-F-S-A-Y-V-D-E-L-S-L-P-F-L-E-D-A-E-I-D-Y-V-T-D-K-M-G-S-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-A-D-D-A-P-L-L-E-R-V-E-Y-A-I-Q-T-Q-V-N-P-Q-L-A-G-H-G-G-H-V-K-L-M-E-I-T-D-A-G-V-A-I-V-A-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-E-G-I-E-K-E-L-L-Q-Q-F-S-G-E-L-T-A-V-R-D-A-T-E-H-D-R-G-D-H-S-Y-Y


### FUNCTION A GTPase-activating protein  that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-S-R-K-K-K-S-R-K-P-G-A-A-G-A-P-E-F-M-V-T-R-N-R-S-E-S-D-V-A-G-R-L-R-K-K-D-K-K-R-K-G-L-K-A-G-G-R-N-S-E-E-G-A-Q-Q-K-H-G-S-S-Q-V-R-D-P-R-L-G-S-K-K-K-I-P-L-I-V-E-P-A-K-K-L-T-K-Q-E-R-R-L-S-A-E-Q-E-L-E-M-L-E-N-D-A-K-L-N-V-L-L-D-R-I-E-S-G-E-N-L-G-R-G-L-Q-Q-Y-V-D-E-K-L-D-R-I-E-Q-L-M-S-Q-L-G-L-L-E-P-E-A-E-E-E-F-E-D-E-A-P-V-R-K-S-R-S-D-D-D-L-L-A-D-F-E-D-F-D-M-D-D-Y-K-G


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-W-E-L-V-L-I-F-V-V-G-L-V-V-L-G-P-E-R-L-P-H-A-I-R-S-V-A-R-F-V-S-A-A-K-S-M-A-N-S-V-K-D-E-L-A-H-E-L-K-V-Q-E-L-Q-E-N-L-R-K-A-E-Q-M-G-M-E-E-L-S-P-D-L-K-A-S-V-E-Q-L-K-Q-A-A-Q-S-V-N-R-P-Y-A-D-V-S-A-K-N-E-A-T-S-S-S-S-S-D-A-T-H-Q-T-E-A-T-K-T-S-A-A-N-T-K-S-E


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-I-S-I-W-Q-L-L-I-I-A-V-I-V-V-L-L-F-G-T-K-K-L-R-G-I-G-S-D-L-G-G-A-I-K-G-F-K-K-A-M-N-E-E-E-S-E-K-K-D-A-D-F-E-P-K-S-L-E-Q-Q-N-K-Q-A-A-T-E-S-K-K-D-K-E-Q-A


### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate  for the ubiquinone pathway ### SEQUENCE -M-N-Q-P-N-S-L-Y-L-A-L-L-I-E-A-K-W-Q-N-P-E-D-F-H-F-S-S-D-F-A-K-H-W-L-L-E-Q-G-S-L-S-R-R-L-A-R-H-C-Q-H-L-T-V-E-L-M-R-N-E-K-S-G-V-G-Q-L-T-M-Q-E-T-Q-G-L-S-P-E-I-C-L-I-R-E-V-V-L-S-G-D-Q-T-P-W-V-L-G-R-T-L-I-P-E-T-T-L-A-D-Q-P-Y-D-L-A-T-L-G-D-I-P-L-G-L-T-V-F-S-A-E-Q-V-E-R-D-A-L-Q-V-A-W-I-E-T-P-Q-G-R-L-L-A-R-R-S-R-L-W-M-N-H-K-P-M-L-V-A-E-L-F-L-P-D-A-P-I-Y-S-R-E-S-V


### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-E-Q-F-K-H-I-D-V-Q-G-A-H-A-L-I-S-R-G-E-A-R-L-V-D-I-R-D-P-Q-S-F-A-V-A-H-A-Q-S-A-F-H-L-T-N-D-S-I-V-N-F-M-Q-Q-V-E-F-E-Q-P-V-L-V-M-C-Y-H-G-I-S-S-Q-G-A-A-Q-Y-L-V-N-Q-G-F-E-E-V-Y-S-V-D-G-G-F-E-A-W-H-R-A-S-L-P-V-E-A-S


### FUNCTION Involved in iron-sulfur  cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-N-T-E-F-H-Q-L-V-D-N-E-L-Q-L-I-E-E-A-I-D-E-S-G-A-D-I-D-Y-E-T-T-G-N-V-M-T-L-E-F-D-D-R-S-Q-I-I-I-N-R-Q-E-P-M-Q-E-I-W-L-A-S-K-S-G-G-F-H-F-Q-Y-K-A-G-Q-W-I-C-S-K-T-G-V-E-F-A-H-M-V-K-Q-E-C-E-K-H-A-G-E-S-I-D-W-A


### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-S-F-N-P-E-L-A-T-K-T-L-E-A-E-G-L-R-C-P-E-P-V-M-M-V-R-K-T-I-R-T-M-Q-D-G-E-V-L-L-V-K-A-D-D-P-S-T-T-R-D-I-P-S-F-C-R-F-M-D-H-Q-L-I-A-A-Q-T-D-E-L-P-Y-Q-Y-L-I-K-K-G-L


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-T-Y-A-F-N-R-E-L-R-L-L-T-P-E-H-Y-Q-N-V-F-Q-Q-A-H-R-A-G-S-P-H-F-T-I-I-A-R-N-N-N-L-S-H-P-R-L-G-L-A-V-P-K-K-Q-I-K-T-A-V-G-R-N-R-F-K-R-L-A-R-E-S-F-R-N-T-Q-H-Q-L-P-N-K-D-F-V-V-I-A-K-K-S-A-Q-D-L-S-N-E-E-L-F-K-L-F-D-K-L-W-H-R-L-S-R-P-S-R-G


### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-K-V-D-H-T-K-M-P-A-P-A-V-R-L-A-K-T-M-T-T-P-K-G-D-E-I-A-V-F-D-L-R-F-C-R-P-N-Q-E-I-L-S-E-K-G-I-H-T-L-E-H-L-F-A-G-F-M-R-E-H-L-N-G-E-G-I-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-V-P-K-N-A-R-V-L-E-A-W-R-R-S-M-E-D-I-L-T-L-K-S-E-E-E-I-P-E-L-N-I-Y-Q-C-G-T-A-C-M-H-S-L-K-E-A-Q-E-I-A-R-T-V-L-D-R-G-I-S-I-M-D-N-E-A-L-K-L-Q-L


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-I-G-H-S-T-Q-E-K-I-E-K-L-V-Q-S-C-G-C-N-L-Y-D-L-L-L-L-K-E-N-E-R-S-I-L-R-L-Y-I-T-K-E-V-G-V-S-L-D-D-C-A-M-V-S-D-L-I-S-P-L-L-D-V-E-D-P-L-A-G-E-Y-F-L-E-V-S-S-P-G-I-E-R-P-L-K-R-P-A-H-Y-Q-H-A-L-G-E-L-A-R-I-K-F-A-D-K-N-E-I-E-G-E-I-E-A-A-D-E-T-S-V-K-L-K-G-E-E-P-I-P-Y-S-L-I-K-K-A-Q-T-F-Y-R-W


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-E-K-S-V-K-L-Q-R-T-E-S-L-L-K-E-V-I-P-E-A-L-S-T-L-S-D-T-R-L-N-S-L-G-V-V-E-V-D-C-S-K-G-K-Y-H-A-E-V-Y-L-D-A-P-F-A-T-P-E-E-K-R-E-I-L-R-Q-L-R-L-A-E-G-T-I-R-D-H-C-L-S-A-T-G-W-F-K-C-P-R-F-H-F-N-F-D-D-S-T-D-K-A-N-R-L-D-A-I-F-E-Q-L-K-K-E-R-E-S


### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-E-F-E-V-K-S-P-I-L-G-F-E-S-V-R-G-M-R-L-E-K-I-D-D-L-F-M-K-L-K-N-A-E-A-D-S-P-V-F-T-L-V-N-P-F-L-L-R-E-Y-D-F-E-I-P-L-A-M-K-V-L-L-D-L-K-E-N-T-N-L-L-V-L-N-I-M-I-I-H-T-P-L-E-S-S-T-V-N-F-L-A-P-V-I-F-N-F-D-N-H-T-M-G-Q-L-V-L-E-S-H-R-Y-P-A-Y-G-L-A-E-T-I-S-S-F-F-N-S-D-S-T-P-T-Q-E-A


### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-F-L-D-K-F-F-G-K-E-K-S-S-A-K-S-A-S-D-R-L-K-L-V-L-A-H-E-R-A-V-N-L-P-Y-L-E-E-M-K-R-E-I-L-E-V-I-K-K-Y-T-H-A-E-K-I-E-I-K-A-D-S-N-Q-Q-I-D-T-L-E-V-E-I-V-L-G-K-N-S


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-T-M-F-I-V-K-P-T-L-T-P-E-E-I-V-E-K-I-N-F-Y-K-E-A-I-I-K-N-G-G-E-I-C-A-T-Q-D-M-G-M-R-N-L-A-Y-E-I-N-K-N-K-R-G-Y-Y-F-V-V-Y-F-K-S-A-P-S-L-V-I-E-L-E-R-L-Y-R-I-N-E-D-I-L-R-F-I-V-I-K-Y-E-S-K-K-E-Q-N-A-W-N-T-M-V-D-K-V-N-K-K-A-E-A-P-K-S-A-P-V-A-A-P-E-T-A-P-V-A-P-E-A-T-P-E-A


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-E-K-K-R-Y-S-K-R-Y-C-K-Y-T-E-A-K-I-E-F-I-D-Y-K-D-V-E-M-L-K-H-S-L-S-E-R-Y-K-I-M-P-R-R-L-T-G-N-S-K-R-W-Q-E-R-V-E-V-A-I-K-R-A-R-H-M-A-L-I-P-Y-I-I-D-R-K-K-V-V-E-N-P-F-K-I


### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-V-Y-E-L-K-S-P-L-L-G-F-E-E-I-K-E-F-D-L-V-E-V-D-E-M-F-A-K-I-K-A-I-N-N-P-S-I-E-I-T-L-A-N-P-Y-A-L-R-E-Y-S-F-D-I-P-A-Y-I-Q-A-L-L-D-I-N-A-Q-S-K-V-R-V-F-C-T-V-V-I-Q-N-P-I-D-E-S-R-V-N-F-L-A-P-L-I-F-N-D-D-N-Q-T-A-A-Q-I-A-L-S-I-K-D-Y-P-D-F-S-V-A-D-K-I-K-N-Y-V-K-E


### FUNCTION Participates in the translocation of lipoproteins from the inner membrane to the outer membrane Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate ### SEQUENCE -M-R-I-A-L-L-W-V-A-F-G-A-L-A-L-A-A-F-E-S-I-G-S-F-R-S-E-F-V-Q-T-I-R-S-E-D-G-K-I-I-E-Y-R-G-R-V-Y-A-K-S-P-Y-Y-G-L-W-K-Y-E-K-P-M-E-K-E-I-Y-I-V-D-K-Q-V-V-I-Y-E-P-A-L-E-Q-A-T-V-S-S-L-Q-N-S-I-D-F-M-A-L-L-R-Q-S-K-R-N-S-E-G-I-Y-E-A-T-V-F-E-Q-K-Y-Q-I-L-A-D-E-K-G-E-P-Q-K-V-F-F-I-D-K-L-H-N-E-V-Q-I-I-F-K-N-A-E-I-N-P-V-L-E-K-E-M-F-L-F-M-P-S-G-E-I-D-L-I-R-Q


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Q-T-L-L-A-I-F-V-G-A-G-F-G-A-L-L-R-W-F-L-G-L-K-L-N-A-L-A-P-L-I-P-L-G-T-L-G-A-N-W-L-G-G-Y-L-I-G-L-A-L-A-F-F-S-T-H-P-L-L-S-P-E-W-R-L-L-I-I-T-G-F-L-G-G-L-T-T-F-S-T-F-S-A-E-M-V-S-L-L-Q-W-G-R-Y-G-A-L-A-L-G-V-A-L-H-V-G-G-S-I-G-M-T-L-L-G-I-F-T-F-S-F-I-Q-R-I-G-G


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-I-E-L-L-L-L-S-L-A-L-S-M-D-A-F-A-V-S-L-G-L-G-A-R-F-G-Y-N-K-R-E-S-L-R-P-A-L-S-F-G-I-F-Q-G-I-M-P-L-L-G-F-F-V-G-V-T-F-I-A-F-I-S-A-F-D-H-Y-L-A-F-G-I-L-A-L-I-G-A-K-M-I-Y-E-G-L-S-Q-S-E-E-E-R-L-D-E-L-S-H-R-T-L-L-I-L-S-I-A-T-S-I-D-A-L-A-A-G-V-S-L-H-L-I-D-V-N-V-F-L-S-C-T-I-I-A-F-T-T-F-L-L-S-Y-L-G-V-L-W-G-K-R-A-G-E-Q-C-K-R-G-A-E-I-L-G-G-V-I-L-I-G-I-G-S-K-I-L-L-E-H-L-F-F


### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-I-L-S-R-K-E-E-E-S-I-V-I-G-D-E-I-V-I-K-V-V-S-I-D-K-G-S-V-K-L-G-F-E-A-P-P-H-M-L-I-L-R-E-E-L-K-K-A-V-A-D-E-N-L-K-A-S-A-Q-S-D-E-I-A-L-T-S-L-S-Q-K-L-K-K


### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-K-T-K-E-E-V-V-G-T-P-R-E-I-F-A-P-N-G-H-W-I-S-R-R-Y-L-L-A-G-E-G-M-G-F-S-F-H-E-T-I-I-L-A-G-T-K-T-H-I-H-Y-Q-N-H-L-E-A-V-F-C-V-Q-G-R-G-E-V-E-L-I-P-S-G-E-R-F-L-I-E-E-G-V-M-Y-A-L-D-K-H-D-E-H-Y-L-S-A-S-E-E-M-R-L-I-C-V-F-N-P-P-L-Q-G-N-E-V-H-D-E-K-G-V-Y-P-L-K-K-G-Q


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-Y-S-I-V-T-A-L-L-E-L-C-E-N-H-A-K-S-N-K-A-K-K-V-T-K-V-V-V-A-L-G-E-R-S-G-V-E-P-Q-L-L-E-S-A-F-E-V-F-K-L-D-S-V-C-A-E-S-E-L-V-I-E-T-K-P-M-K-F-R-C-R-S-C-G-A-E-F-L-P-K-G-I-D-F-G-S-C-E-V-C-K-A-P-N-P-E-L-V-G-G-K-E-M-H-L-Q-S-L-E-M-E-A-E-D-E-G


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-Q-I-D-D-K-L-L-A-R-L-E-S-L-A-M-I-E-V-P-E-E-K-K-E-S-I-K-A-E-L-G-E-I-V-N-F-V-E-N-L-N-S-L-E-V-E-G-L-E-A-T-F-T-T-L-E-G-K-T-P-M-R-E-D-T-P-M-N-D-E-E-I-P-A-L-I-L-K-H-A-P-Q-S-A-E-N-Y-F-I-V-P-K-I-I-E


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-D-F-D-N-Q-T-D-T-N-L-D-I-T-L-L-E-S-I-A-T-F-L-S-P-R-E-V-E-L-I-L-L-D-D-E-A-M-R-K-I-N-Q-E-H-R-G-I-D-K-S-T-D-V-L-S-F-P-L-E-G-G-D-F-L-P-L-G-S-I-L-L-S-I-D-R-V-R-A-E-A-E-L-R-G-H-S-I-E-A-E-A-A-L-L-F-I-H-G-M-L-H-L-L-G-Y-D-H-E-Y-D-Q-G-E-Q-R-F-K-E-E-E-L-I-T-R-F-G-L-P-S-S-L-I-V-R-T-E-E-L


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-M-E-L-L-K-L-N-I-V-T-P-Q-G-S-I-F-S-G-D-V-K-S-V-T-L-P-G-A-E-G-E-F-G-V-L-P-G-H-A-D-L-L-S-L-L-N-A-G-A-I-E-F-E-K-S-N-G-K-T-E-L-V-A-V-N-W-G-Q-V-K-V-D-A-V-S-V-D-V-L-A-D-G-A-I-A-I-G-G-D-S-E-S-E-V-A-M-A-I-A-N-A-R-T-L-L-E-E-A-T-D-N-N-V-A-I-S-S-V-V-S-R-I-E-S-A-A-K-N-S-L


### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-G-I-H-P-N-Y-V-P-C-K-V-T-C-V-T-S-G-K-E-F-E-V-L-S-T-K-P-E-L-R-I-D-I-S-S-F-C-H-P-F-Y-T-G-S-D-K-V-V-D-T-A-G-R-V-E-K-F-K-Q-K-Y-N-M-K


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-V-A-K-G-S-D-F-E-T-E-I-K-E-E-I-I-V-A-E-P-R-R-F-K-V-I-L-L-N-D-D-Y-S-T-M-D-F-V-V-E-V-L-M-V-I-F-N-K-N-F-D-E-A-L-G-V-M-L-K-V-H-N-E-G-R-G-V-C-G-I-Y-P-Y-D-V-A-E-T-K-V-S-Q-V-K-K-K-A-E-E-S-G-F-P-L-R-A-I-L-E-E-C


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-Q-R-M-E-E-I-A-F-K-A-L-N-R-V-N-N-D-R-Y-L-L-A-N-I-L-F-A-R-I-D-E-L-S-K-G-A-K-P-L-V-N-M-D-V-K-K-H-K-L-T-D-I-A-M-T-E-V-A-E-G-K-I-A-L-S-Q-I-D-Q-L


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-M-P-S-M-P-E-L-L-V-I-L-A-I-V-V-L-L-F-G-A-K-K-I-P-D-L-A-K-G-L-G-S-G-I-K-N-F-K-K-A-M-K-E-D-E-E-S-E-V-S-V-T-K-S-E-K-I-E-E-A-P-K-N-E-K-S-A-S-T-P-I-Q-D-T-T-K-Q-A


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-K-I-R-V-Y-C-I-S-K-P-E-K-D-A-Y-A-E-L-G-E-H-F-K-K-L-A-R-S-F-N-V-E-L-E-I-L-D-I-F-N-K-Q-I-A-Q-A-Q-K-A-A-N-E-A-E-S-S-L-A-Y-K-E-A-L-Q-R-Y-L-S-G-A-H-N-I-A-L-T-P-E-G-K-L-Y-D-S-H-A-F-S-Q-I-F-H-H-K-Q-E-V-N-F-F-I-G-G-A-Y-G-F-E-P-G-F-L-K-S-C-H-Q-S-L-S-L-S-P-L-T-L-G-H-K-V-A-K-V-V-L-C-E-Q-I-Y-R-G-L-T-I-M-H-N-H-P-Y-H-K


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-G-R-I-L-A-I-D-Y-G-R-K-R-T-G-L-A-V-T-D-P-L-K-I-I-P-G-G-L-T-T-V-P-T-H-T-L-L-D-F-L-R-D-Y-V-S-R-E-P-V-E-R-F-V-L-G-L-P-R-R-M-N-Y-E-E-S-E-S-M-T-Y-I-R-P-F-A-V-K-L-A-Q-A-F-P-S-I-P-I-T-Y-V-D-E-R-F-T-S-R-M-A-Q-R-T-I-L-E-A-G-I-G-K-M-K-R-R-D-K-A-L-V-D-E-V-S-A-V-I-I-L-Q-S-Y-L-D-N-P-D-R


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-L-L-P-I-Y-L-Y-G-H-P-V-L-R-K-V-A-E-D-I-T-P-D-Y-P-K-L-K-E-L-I-A-N-M-T-E-S-M-Y-H-S-D-G-I-G-L-A-A-P-Q-I-G-L-P-I-R-V-L-V-I-D-A-D-P-L-K-E-D-Y-P-E-C-A-G-F-K-R-V-M-I-N-A-H-I-E-E-R-G-E-D-L-C-T-E-Y-E-G-C-L-S-L-P-A-I-H-E-K-V-E-R-P-T-S-I-R-I-R-Y-V-D-E-D-F-Q-P-H-E-E-V-L-Q-G-F-A-A-R-V-V-Q-H-E-Y-D-H-I-D-G-K-L-F-I-D-H-I-S-P-I-R-K-Q-L-I-K-G-K-L-Q-N-I-I-K-G-K-V-R-T-S-Y-R-V-V-T-A-P-T-G-K-K-R


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-K-I-V-L-L-V-V-G-K-T-D-S-K-L-M-V-Q-A-T-E-E-Y-I-R-R-L-S-H-Y-V-S-F-E-V-E-V-I-P-D-V-R-L-G-S-K-L-S-S-E-Q-Q-K-D-A-E-G-R-E-I-L-A-R-L-R-P-S-D-S-T-V-L-L-D-E-R-G-R-E-Y-S-S-M-E-F-S-A-F-L-Q-K-K-M-L-I-G-T-R-R-M-V-F-V-I-G-G-P-Y-G-F-S-P-A-V-Q-E-A-V-T-D-R-I-S-L-S-R-M-T-F-S-H-Q-M-I-R-L-F-F-T-E-Q-V-Y-R-A-M-T-I-L-N-H-E-P-Y-H-H-E


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-Q-Q-L-V-R-K-G-R-E-S-F-A-D-K-S-K-S-P-A-L-N-S-C-P-Q-R-R-G-V-C-V-R-V-Y-T-T-T-P-K-K-P-N-S-A-M-R-K-V-A-R-V-R-L-T-N-S-K-E-V-N-A-Y-I-P-G-E-G-H-N-L-Q-E-H-S-I-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-T-A-G-V-N-G-R-T-Q-R-R-S-K-Y-G-A-K-R-P-K-P-G-Q-A-P-A-A-K-G-K-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-A-K-P-K-K-R-Q-I-L-P-D-P-V-Y-G-D-V-R-V-T-K-F-V-N-H-L-M-Y-D-G-K-K-N-T-A-F-S-I-F-Y-G-A-L-D-I-V-K-T-K-H-S-N-E-E-K-S-A-L-E-I-W-K-A-A-L-D-N-I-T-P-Q-V-E-V-K-S-R-R-I-G-G-A-T-F-Q-V-P-T-E-I-R-P-E-R-K-E-S-I-S-M-K-N-L-I-L-Y-A-R-K-R-G-G-K-T-M-A-D-K-L-A-A-E-I-V-D-A-F-N-N-Q-G-A-A-F-K-R-K-E-D-M-H-R-M-A-E-A-N-R-A-F-A-H-F-R-F


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-Q-K-I-R-I-K-L-K-S-Y-D-Y-M-L-V-D-K-S-A-E-K-I-V-K-T-V-K-A-A-G-A-M-V-S-G-P-I-P-L-P-T-H-K-R-I-F-T-V-N-R-S-T-F-V-N-K-K-S-R-E-Q-F-E-L-S-S-Y-K-R-L-I-D-I-Y-N-S-T-A-K-T-V-D-A-L-M-K-L-E-L-P-S-G-V-E-V-E-I-K-V


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-L-K-K-G-P-Y-I-N-L-K-L-E-K-K-V-L-A-M-N-E-S-G-K-K-A-V-I-K-T-W-A-R-A-S-M-I-S-P-D-F-V-G-H-T-I-A-V-H-N-G-N-K-F-I-P-V-F-V-T-E-N-M-V-G-H-K-L-G-E-F-S-P-T-R-T-F-R-G-H-A-G-N-K-K-K


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-G-A-R-K-H-N-S-A-E-A-R-K-E-A-L-K-Q-M-Y-F-A-K-L-R-N-V-P-T-S-P-R-K-M-R-L-V-A-D-M-I-R-G-M-E-V-N-R-A-L-G-V-L-K-F-S-N-K-E-A-S-A-R-V-E-K-L-L-R-S-A-V-A-N-W-E-E-K-N-E-R-K-A-E-E-G-E-L-F-V-S-R-I-C-V-D-G-A-S-T-L-K-R-L-R-P-A-P-Q-G-R-G-Y-R-I-R-K-R-S-N-H-V-T-I-Y-V-D-T-L-N-N-D-N-N


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-K-T-K-F-R-R-Q-Q-K-G-R-M-K-G-F-A-Q-R-G-N-Q-L-S-F-G-S-F-G-I-K-S-L-Q-S-K-W-I-T-G-R-Q-I-E-A-A-R-I-A-V-T-R-Y-M-Q-R-Q-G-Q-V-W-V-R-I-F-P-D-K-P-I-T-K-K-G-E-G-V-R-M-G-K-G-K-G-A-P-E-G-F-V-A-P-I-T-P-G-R-I-I-F-E-V-E-G-V-P-Y-E-I-A-K-E-A-L-R-L-A-A-Q-K-L-P-V-T-T-K-F-V-V-R-H-D-Y-D-I-Q-N-Q-N-A


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-N-L-R-K-E-R-V-G-V-V-S-S-N-K-M-D-K-T-I-T-V-A-V-K-W-K-E-K-H-P-I-Y-G-K-F-V-N-K-T-K-K-Y-H-A-H-D-E-K-N-E-C-G-I-G-D-T-V-R-I-M-E-T-R-P-L-S-R-T-K-R-W-R-L-T-E-I-I-E-R-A-K


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-V-V-A-D-N-S-G-A-K-E-A-L-C-I-R-V-L-G-G-T-R-R-R-Y-A-S-V-G-D-I-I-V-V-S-V-K-S-V-I-P-S-S-D-I-K-K-G-A-V-S-K-A-V-I-V-R-T-K-K-E-V-R-R-P-D-G-S-Y-I-R-F-D-D-N-A-C-V-L-L-N-A-A-G-D-I-R-G-S-R-I-F-G-P-V-A-R-E-L-R-G-T-N-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-K-L-H-I-K-K-G-D-T-V-M-V-I-S-G-E-D-K-G-H-S-G-R-V-L-E-V-L-V-K-E-Q-R-A-I-V-E-G-L-N-M-I-K-K-H-A-K-P-S-A-K-N-P-Q-G-G-I-I-S-K-E-A-P-I-H-I-S-N-L-N-V-V-D-P-K-T-G-K-A-T-R-I-G-R-R-L-N-E-N-G-K-L-V-R-Y-A-K-K-S-G-E-E-I-K


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-A-T-A-N-L-K-K-D-Y-Q-E-R-I-V-P-A-L-M-K-Q-F-G-Y-T-S-V-M-Q-V-P-V-L-K-K-I-V-I-N-Q-G-L-G-M-A-T-G-D-K-K-I-I-D-V-A-V-S-E-L-T-A-I-T-G-Q-K-A-V-P-T-V-S-K-K-D-I-S-N-F-K-L-R-K-K-M-P-I-G-V-M-V-T-L-R-R-E-Q-M-Y-E-F-L-E-R-L-V-R-I-A-L-P-R-I-R-D-F-K-G-I-E-S-K-L-D-G-R-G-N-Y-T-L-G-I-N-E-Q-I-I-F-P-E-I-N-I-D-A-I-T-K-I-L-G-M-N-I-T-F-V-T-S-A-Q-S-D-E-E-G-Y-A-L-L-K-E-F-G-L-P-F-K-N-A-K-K-Q-N


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-E-S-M-K-A-R-E-V-K-R-A-K-L-V-A-K-Y-A-A-K-R-A-A-L-K-A-E-G-N-Y-E-A-L-Q-L-L-P-K-N-A-S-P-V-R-L-H-N-R-C-S-M-T-G-R-P-K-G-Y-M-R-Q-F-G-I-S-R-I-Q-F-R-E-M-A-S-A-G-L-I-P-G-V-K-K-A-S-W


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-D-P-I-A-D-Y-L-T-R-L-R-N-A-I-M-A-G-H-R-V-V-S-V-P-A-S-N-I-K-K-E-I-T-K-I-L-F-D-K-G-Y-I-L-N-Y-K-F-E-E-N-D-S-Q-G-I-I-K-V-A-L-K-Y-D-L-A-H-K-V-N-A-I-K-K-L-K-R-V-S-R-P-G-L-R-K-Y-V-G-Y-R-D-M-P-R-V-L-N-G-L-G-I-A-I-V-S-T-P-R-G-V-M-T-D-K-E-A-R-E-L-K-V-G-G-E-V-L-C-Y-V-Y


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-L-P-I-S-I-P-A-G-V-T-V-S-H-K-D-E-I-V-T-V-K-G-P-K-G-E-L-S-Q-Y-V-D-P-R-I-T-V-V-I-E-G-G-M-I-H-L-E-R-K-T-D-D-R-I-E-R-S-L-H-G-L-Y-R-S-L-I-N-N-M-V-Q-G-V-S-A-G-F-K-R-E-L-E-L-V-G-V-G-Y-R-A-S-N-Q-G-Q-L-L-E-L-S-L-G-F-T-H-S-I-F-M-Q-L-P-K-E-V-T-V-E-T-K-S-E-R-N-K-N-P-L-I-I-L-E-S-A-D-K-Q-L-L-G-Q-V-C-M-K-I-R-S-F-R-K-P-E-P-Y-K-G-K-G-V-K-F-V-G-E-Q-I-R-R-K-S-G-K-S-A-G-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-V-T-K-E-Q-R-R-Q-K-I-K-A-R-V-R-G-K-I-S-G-T-Q-E-K-P-R-L-T-V-F-R-S-N-K-Q-I-Y-A-Q-L-I-D-D-I-A-G-R-T-L-A-S-A-S-S-L-K-L-E-M-T-G-S-K-K-E-I-A-A-K-V-G-D-E-I-A-K-A-A-T-E-A-G-I-S-T-V-V-F-D-R-N-G-Y-L-F-H-G-R-I-K-E-L-A-D-A-A-R-K-G-G-L-K-F


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-I-V-Y-N-R-V-K-S-T-N-D-L-E-L-K-D-R-L-V-A-I-N-R-V-T-K-V-T-K-G-G-R-T-F-T-F-A-A-I-V-V-V-G-N-E-D-G-V-I-G-W-G-L-G-K-A-G-E-V-P-A-A-I-A-K-G-V-E-A-A-K-K-N-L-I-R-V-P-V-H-N-G-T-I-P-H-E-Q-A-A-S-Y-G-G-A-S-V-F-L-K-P-A-T-T-G-T-G-V-K-A-G-G-A-M-R-A-V-L-D-S-V-G-V-T-D-V-L-A-K-S-K-G-S-S-N-P-H-N-L-V-K-A-T-I-Q-A-L-A-E-M-R-S-P-L-M-V-A-Q-N-R-G-I-S-V-E-K-V-F-K-G


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-N-L-S-S-L-K-P-A-E-G-A-V-K-S-R-K-R-I-G-R-G-P-G-S-G-L-G-G-T-S-T-R-G-H-K-G-A-K-S-R-S-G-Y-S-K-K-I-G-F-E-G-G-Q-M-P-I-Q-R-R-L-P-K-F-G-F-K-N-I-N-R-V-E-Y-K-P-I-N-L-S-V-L-Q-T-L-S-E-A-N-S-L-T-K-I-S-V-E-D-L-I-A-A-G-L-V-S-R-N-S-L-V-K-I-L-A-N-G-T-V-T-T-A-L-T-V-E-A-H-A-F-S-K-T-A-E-E-A-I-V-R-A-G-G-S-V-V-K-L


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-Q-T-A-I-E-Q-D-G-V-I-L-E-A-L-S-N-A-M-F-K-V-E-L-Q-N-G-H-V-I-T-A-H-I-S-G-K-M-R-M-H-Y-I-K-I-L-P-G-D-K-V-K-V-E-M-S-P-Y-D-L-T-K-G-R-I-S-F-R-Y-K


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-I-R-I-V-G-V-D-L-P-Q-N-K-R-G-F-I-A-L-T-Y-I-Y-G-I-G-R-S-S-A-I-T-I-L-D-K-A-G-V-D-R-D-I-K-V-K-D-W-S-D-D-Q-A-A-A-I-R-D-V-I-G-A-G-Y-K-V-E-G-D-L-R-S-E-V-Q-L-N-I-K-R-L-M-D-I-G-C-Y-R-G-I-R-H-R-I-G-L-P-L-R-G-Q-S-T-K-N-N-A-R-T-R-K-G-K-K-K-T-V-A-N-K-K-K-A-T-K


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-K-A-V-A-K-K-K-V-V-R-V-E-A-V-G-Q-A-H-I-H-S-S-F-N-N-I-I-I-S-L-A-N-S-E-G-Q-V-I-S-W-S-S-A-G-K-M-G-F-R-S-S-K-K-N-T-P-Y-A-A-Q-M-A-A-Q-D-C-A-K-V-A-Y-D-M-G-L-R-K-V-T-V-Y-V-K-G-P-G-N-G-R-E-S-A-I-R-T-I-H-G-A-G-I-E-V-M-E-I-I-D-V-T-P-M-P-H-N-G-C-R-P-P-K-K-R-R-V


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-E-I-K-E-L-I-A-K-A-T-A-N-M-E-K-A-V-E-Y-L-D-E-Q-L-S-H-V-R-A-G-K-A-S-P-K-L-L-D-G-I-M-V-M-Y-Y-G-N-A-T-P-L-T-Q-V-A-S-I-N-T-P-D-A-K-T-I-V-V-T-P-W-E-R-S-L-I-K-D-I-E-K-A-I-M-D-S-P-L-G-I-T-P-E-N-N-G-E-L-I-R-L-G-L-P-P-L-T-E-E-R-R-R-Q-L-V-K-Q-T-K-G-D-A-E-D-A-K-V-S-V-R-N-A-R-R-D-A-I-D-A-I-K-K-S-V-K-T-D-G-T-P-E-D-V-A-K-D-A-E-A-E-M-Q-K-V-H-D-R-Y-I-K-K-I-D-E-L-F-A-E-K-E-K-E-I-M-T-V