### FUNCTION Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival ### SEQUENCE -M-K-F-N-D-V-Y-N-K-H-H-K-I-I-H-H-L-L-K-K-Y-N-I-S-Y-N-Y-D-E-Y-Y-Q-L-L-L-I-K-M-W-Q-L-S-Q-I-Y-K-P-S-S-K-Q-S-L-S-S-F-L-F-T-R-L-N-F-Y-L-I-D-L-F-R-Q-Q-N-Q-L-K-D-V-I-L-C-E-N-N-S-P-T-L-T-E-Q-P-T-Y-F-N-E-H-D-L-R-L-Q-D-I-F-K-L-L-N-Q-R-E-R-L-W-L-K-L-Y-L-E-G-Y-K-Q-F-E-I-A-E-I-M-S-L-S-L-S-T-I-K-L-I-K-M-S-V-K-R-K-C-Q-H-N-F-N


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-K-V-N-P-N-N-I-E-L-I-I-S-A-V-K-E-E-Q-Y-P-K-T-E-L-S-E-V-A-L-S-G-R-S-N-V-G-K-S-T-F-I-N-S-M-I-G-R-K-N-M-A-R-T-S-Q-Q-P-G-K-T-Q-T-L-N-F-Y-N-I-D-E-Q-L-I-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-T-Q-R-E-K-F-G-K-M-I-E-E-Y-I-T-K-R-E-N-L-Q-L-V-I-Q-L-V-D-L-R-H-D-P-T-Q-D-D-I-L-M-Y-N-Y-L-K-H-F-D-I-P-T-L-V-I-C-T-K-E-D-K-I-P-K-G-K-V-Q-K-H-I-K-N-I-K-T-Q-L-D-M-D-P-D-D-T-I-V-S-Y-S-S-I-Q-N-N-K-Q-Q-Q-I-W-N-L-I-E-P-Y-I-S


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-F-T-I-D-F-S-D-H-T-G-L-V-K-D-A-W-Y-K-Q-I-E-D-L-L-E-F-A-K-K-E-E-H-I-E-D-D-A-E-L-S-V-T-F-V-D-K-Q-E-I-Q-E-I-N-R-T-Y-R-D-K-D-K-V-T-D-V-I-S-F-A-L-E-E-D-E-P-E-I-D-F-S-G-L-D-I-P-R-V-L-G-D-I-I-I-C-T-D-V-A-Q-E-Q-A-N-N-Y-G-H-S-F-E-R-E-L-G-F-L-A-L-H-G-F-L-H-L-L-G-Y-D-H-M-T-E-A-D-E-K-E-M-F-G-R-Q-D-T-I-L-N-A-Y-G-L-T-R-G


### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-D-N-H-G-I-L-E-S-L-L-F-T-A-G-D-E-G-L-D-E-K-Q-L-L-E-I-L-D-M-S-K-N-Q-L-V-E-L-I-E-N-Y-S-S-H-G-L-M-I-Q-R-F-G-T-T-Y-V-L-T-T-K-K-E-A-A-T-Y-I-E-Q-L-I-E-Q-K-S-Q-M-K-L-S-Q-A-A-M-E-V-L-S-I-I-A-Y-N-Q-P-L-S-R-S-D-I-E-L-I-R-S-I-N-S-D-G-A-V-K-T-L-I-A-K-G-L-V-E-A-K-V-V-N-E-Q-R-S-Q-Q-L-I-T-T-D-L-F-L-N-V-F-G-I-S-N-I-E-D-L-P-T-T-E-E-D-D-E-E-M-D-A-F-F-S-N-L-V-N-Q-K-G-E-N-N-D


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-K-I-T-E-Q-V-E-V-I-V-K-P-I-M-E-D-L-N-F-E-L-V-D-V-E-Y-V-K-E-G-R-D-H-F-L-R-I-S-I-D-K-E-G-G-V-D-L-N-D-C-T-L-A-S-E-K-I-S-E-A-M-D-A-N-D-P-I-P-E-M-Y-Y-L-D-V-A-S-P-G-A-E-R-P-I-K-K-E-Q-D-F-Q-N-A-I-T-K-P-V-F-V-S-L-Y-V-P-I-E-G-E-K-E-W-L-G-I-L-Q-E-V-N-N-E-T-I-V-V-Q-V-K-I-K-A-R-T-K-D-I-E-I-P-R-D-K-I-A-K-A-R-H-A-V-M-I


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-T-N-H-K-L-I-E-A-V-T-K-S-Q-L-R-T-D-L-P-S-F-R-P-G-D-T-L-R-V-H-V-R-I-I-E-G-T-R-E-R-I-Q-V-F-E-G-V-V-I-K-R-R-G-G-G-V-S-E-T-F-T-V-R-K-I-S-S-G-V-G-V-E-R-T-F-P-L-H-T-P-K-I-E-K-I-E-V-K-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-S-L-R-G-K-A-A-R-I-Q-E-I-R


### FUNCTION Extracellular fibrinogen-binding protein that plays an important role in virulence By interacting with the alpha chain of fibrinogen and its derivative fibrin, enhances a non-functional interaction between fibrinogen and platelets and is responsible for repression of fibrinogen-dependent platelet aggregation In addition, assembles a fibrinogen protective shield around the bacteria which results in impaired phagocytic clearance by the host Mechanistically, interacts with host complement C3b deposited on the surface of the bacterium via its C-terminal and then recruits fibrinogen via its N-terminal ### SEQUENCE -M-K-N-K-L-I-A-K-S-L-L-T-I-A-A-I-G-I-T-T-T-T-I-A-S-T-A-D-A-S-E-G-Y-G-P-R-E-K-K-P-V-S-I-N-H-N-I-V-E-Y-N-D-G-T-F-K-Y-Q-S-R-P-K-F-N-S-T-P-K-Y-I-K-F-K-H-D-Y-N-I-L-E-F-N-D-G-T-F-E-Y-G-A-R-P-Q-F-N-K-P-A-A-K-T-D-A-T-I-K-K-E-Q-K-L-I-Q-A-Q-N-L-V-R-E-F-E-K-T-H-T-V-S-A-H-R-K-A-Q-K-A-V-N-L-V-S-F-E-Y-K-V-K-K-M-V-L-Q-E-R-I-D-N-V-L-K-Q-G-L-V-K


### FUNCTION May be involved in countering the first line of host defense mechanisms Impairs the leukocyte response to FPRL1 agonists by binding directly to host FPRL1 ### SEQUENCE -M-K-K-N-I-T-K-V-I-I-A-S-T-V-I-A-T-G-L-L-T-Q-T-N-D-A-K-A-F-F-S-Y-E-W-K-G-L-E-I-A-K-N-L-A-D-Q-A-K-K-D-D-E-R-A-D-K-L-I-K-E-A-D-E-K-N-E-H-Y-K-G-K-T-V-E-D-L-Y-V-I-A-K-K-M-G-K-G-N-T-I-A-V-V-K-I-K-D-G-G-K-N-G-Y-Y-T-F-D-I-T-R-P-L-E-E-H-R-K-N-I-P-V-V-K-N-G-E-I-D-S-I-T-W-Y


### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-A-V-F-K-V-F-Y-Q-H-N-R-D-E-V-I-V-R-E-N-T-Q-S-L-Y-V-E-A-Q-T-E-E-Q-V-R-R-Y-L-K-D-R-N-F-N-I-E-F-I-T-K-L-E-G-A-H-L-D-Y-E-K-E-N-S-E-H-F-N-V-E-I-A-K


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-A-V-P-N-E-L-K-Y-S-K-E-H-E-W-V-K-V-E-G-N-V-A-T-I-G-I-T-E-Y-A-Q-S-E-L-G-D-I-V-F-V-E-L-P-E-T-D-D-E-I-N-E-G-D-T-F-G-S-V-E-S-V-K-T-V-S-E-L-Y-A-P-I-S-G-K-V-V-E-V-N-E-E-L-E-D-S-P-E-F-V-N-E-S-P-Y-E-K-A-W-M-V-K-V-E-I-S-D-E-S-Q-I-E-A-L-L-T-A-E-K-Y-S-E-M-I-G-E


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-K-S-P-G-T-L-A-E-N-R-K-A-R-H-D-Y-N-I-E-D-T-I-E-A-G-I-V-L-Q-G-T-E-I-K-S-I-R-R-G-S-A-N-L-K-D-S-Y-A-Q-V-K-N-G-E-M-Y-L-N-N-M-H-I-A-P-Y-E-E-G-N-R-F-N-H-D-P-L-R-S-R-K-L-L-L-H-K-R-E-I-I-K-L-G-D-Q-T-R-E-I-G-Y-S-I-V-P-L-K-L-Y-L-K-H-G-H-C-K-V-L-L-G-V-A-R-G-K-K-K-Y-D-K-R-Q-A-L-K-E-K-A-V-K-R-D-V-A-R-D-M-K-A-R-Y


### FUNCTION Dephosphorylates the 5' and 2'-phosphates of deoxyribonucleotides ### SEQUENCE -M-T-R-K-S-I-A-I-D-M-D-E-V-L-A-D-T-L-G-E-I-I-D-A-V-N-F-R-A-D-L-G-I-K-M-E-A-L-N-G-Q-K-L-K-H-V-I-P-E-H-D-G-L-I-T-E-V-L-R-E-P-G-F-F-R-H-L-K-V-M-P-Y-A-Q-E-V-V-K-K-L-T-E-H-Y-D-V-Y-I-A-T-A-A-M-D-V-P-T-S-F-S-D-K-Y-E-W-L-L-E-F-F-P-F-L-D-P-Q-H-F-V-F-C-G-R-K-N-I-V-K-A-D-Y-L-I-D-D-N-P-R-Q-L-E-I-F-T-G-T-P-I-M-F-T-A-V-H-N-I-N-D-D-R-F-E-R-V-N-S-W-K-D-V-E-Q-Y-F-L-D-N-I-E-K


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-S-K-L-I-D-S-F-M-K-L-P-G-I-G-P-K-T-A-Q-R-L-A-F-H-T-L-D-M-K-E-D-D-V-V-Q-F-A-K-A-L-V-D-V-K-R-E-L-T-Y-C-S-V-C-G-H-I-T-E-N-D-P-C-Y-I-C-E-D-K-Q-R-D-R-S-V-I-C-V-V-E-D-D-K-D-V-I-A-M-E-K-M-R-E-Y-K-G-L-Y-H-V-L-H-G-S-I-S-P-M-D-G-I-G-P-E-D-I-N-I-P-S-L-I-E-R-L-K-N-D-E-V-S-E-L-I-L-A-M-N-P-N-L-E-G-E-S-T-A-M-Y-I-S-R-L-V-K-P-I-G-I-K-V-T-R-L-A-Q-G-L-S-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-I-A-G-R-T-E-M


### FUNCTION Virulence factor that is important for the establishment of infection in the host EsxB is required for EsxA synthesis as well as secretion ### SEQUENCE -M-G-G-Y-K-G-I-K-A-D-G-G-K-V-D-Q-A-K-Q-L-A-A-K-T-A-K-D-I-E-A-C-Q-K-Q-T-Q-Q-L-A-E-Y-I-E-G-S-D-W-E-G-Q-F-A-N-K-V-K-D-V-L-L-I-M-A-K-F-Q-E-E-L-V-Q-P-I-A-D-H-Q-K-A-I-D-N-L-S-Q-N-L-A-K-Y-D-T-L-S-I-K-Q-G-L-D-R-V-N-P


### FUNCTION Implements its pathogenic function during infection ### SEQUENCE -M-N-F-N-D-I-E-T-M-V-K-S-K-F-K-D-I-K-K-H-A-E-E-I-A-H-E-I-E-V-R-S-G-Y-L-R-K-A-E-Q-Y-K-R-L-E-F-N-L-S-F-A-L-D-D-I-E-S-T-A-K-D-V-Q-T-A-K-T-S-A-N-K-D-S-V-T-V-K-G-K-A-P-N-T-L-Y-I-E-K-R-N-L-M-K-Q-K-L-E-M-L-G-E-D-I-D-K-N-K-E-S-L-Q-K-A-K-E-I-A-G-E-K-A-S-E-Y-F-N-K-A-M-N


### FUNCTION Component of the ESAT-6 secretion system  Required for the secretion of EsxA and EsxB ### SEQUENCE -M-L-M-N-S-V-I-A-L-T-F-L-T-A-S-S-N-N-G-G-L-N-I-D-V-Q-Q-E-E-E-K-R-I-N-N-D-L-N-Q-Y-D-T-T-L-F-N-K-D-S-K-A-V-N-D-A-I-A-K-Q-K-K-E-R-Q-Q-Q-I-K-N-D-M-F-Q-N-Q-A-S-H-S-T-R-L-N-E-T-K-K-V-L-F-S-K-S-N-L-E-K-T-S-E-S-D-K-S-P-Y-I-Q-N-K-Q-E-K-K-I-F-P-Y-I-L-M-S-V-G-A-F-L-T-L-G-F-V-I-F-S-I-H-K-G-R-R-T-K-N-E-S-A-R-K-S-N-I


### FUNCTION Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB The LrgAB and CidAB proteins may affect the proton motive force of the membrane May be involved in programmed cell death , possibly triggering PCD in response to antibiotics and environmental stresses ### SEQUENCE -M-K-Q-Q-K-D-A-S-K-P-A-H-F-F-H-Q-V-I-V-I-A-L-V-L-F-V-S-K-I-I-E-S-F-M-P-I-P-M-P-G-S-V-I-G-L-V-L-L-F-V-L-L-C-T-G-A-V-K-L-G-E-V-E-K-V-G-T-T-L-T-N-N-I-G-L-L-F-V-P-A-G-I-S-V-V-N-S-L-G-V-I-S-Q-A-P-F-L-I-I-G-L-I-I-V-S-T-I-L-L-L-I-C-T-G-Y-V-T-Q-I-I-M-K-V-T-S-R-S-K-G-D-K-V-T-K-K-I-K-I-E-E-A-Q-A-H-D


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-K-I-T-I-L-A-V-G-K-L-K-E-K-Y-W-K-Q-A-I-A-E-Y-E-K-R-L-G-P-Y-T-K-I-D-I-I-E-V-T-D-E-K-A-P-E-N-M-S-D-K-E-I-E-Q-V-K-E-K-E-G-Q-R-I-L-A-K-I-K-P-Q-S-T-V-I-T-L-E-I-Q-G-K-M-L-S-S-E-G-L-A-Q-E-L-N-Q-R-M-T-Q-G-Q-S-D-F-V-F-V-I-G-G-S-N-G-L-H-K-D-V-L-Q-R-S-N-Y-A-L-S-F-S-K-M-T-F-P-H-Q-M-M-R-V-V-L-I-E-Q-V-Y-R-A-F-K-I-M-R-G-E-A-Y-H-K


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-K-V-K-L-I-C-V-G-K-L-K-E-R-Y-L-K-D-G-I-S-E-Y-Q-K-R-L-S-R-F-C-Q-F-E-M-I-E-L-T-D-E-R-T-P-D-K-A-N-F-A-D-N-Q-L-I-M-S-K-E-A-Q-R-I-H-K-K-I-G-E-R-D-F-V-I-A-L-A-I-E-G-K-Q-F-P-S-E-T-F-S-E-L-I-S-G-V-T-V-K-G-Y-S-T-I-T-F-I-I-G-G-S-L-G-L-D-S-I-I-K-K-R-A-D-M-L-M-S-F-G-L-L-T-L-P-H-Q-L-M-R-L-V-L-T-E-Q-I-Y-R-A-F-M-I-T-K-G-S-P-Y-H-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-A-D-V-K-G-K-G-K-K-G-E-I-K-E-V-P-T-G-Y-A-Q-N-F-L-I-K-K-N-L-A-K-E-A-T-S-Q-S-I-G-E-L-K-G-K-Q-K-A-E-E-K-A-Q-A-E-I-L-A-E-A-Q-A-V-K-A-V-L-D-E-D-K-T-R-V-Q-F-Q-E-K-V-G-P-D-G-R-T-F-G-S-I-T-A-K-K-I-S-E-E-L-Q-K-Q-F-G-V-K-V-D-K-R-H-I-V-L-D-H-P-I-R-A-I-G-L-I-E-V-P-V-K-L-H-K-E-L-T-A-E-I-K-L-A-I-T-E-A


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-D-Y-I-K-G-Q-L-T-K-I-T-A-K-Y-I-V-V-E-A-N-G-L-G-Y-M-I-N-V-A-N-P-Y-S-F-T-D-S-V-N-Q-L-V-T-I-Y-L-H-Q-V-I-R-E-D-A-H-L-L-F-G-F-H-T-K-D-E-K-D-V-F-L-K-L-I-S-V-S-G-I-G-P-T-T-A-L-A-I-V-A-V-D-D-N-E-G-L-V-N-A-I-D-N-S-D-I-K-Y-L-M-K-F-P-K-I-G-K-K-T-A-Q-Q-M-V-L-D-L-A-G-K-F-V-E-A-P-Q-E-T-G-N-T-K-A-R-S-N-K-A-G-N-T-Q-L-D-E-A-I-E-A-L-L-A-L-G-Y-K-A-T-E-L-K-K-I-R-A-F-F-E-G-T-S-E-T-A-E-Q-Y-I-K-S-A-L-K-L-L-M-K-G


### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-K-L-D-V-F-A-G-Q-E-K-S-E-L-S-M-I-E-V-A-R-A-I-L-E-E-R-G-R-D-N-E-M-Y-F-S-D-L-V-N-E-I-Q-N-Y-L-G-K-S-D-A-G-I-R-H-A-L-P-F-F-Y-T-D-L-N-T-D-G-S-F-I-P-L-G-E-N-K-W-G-L-R-S-W-Y-A-I-D-E-I-D-E-E-I-I-T-L-E-E-D-E-D-G-A-Q-K-R-K-K-K-R-V-N-A-F-M-D-G-D-E-D-A-I-D-Y-R-D-D-D-P-E-D-E-D-F-T-E-E-S-A-E-V-E-Y-D-E-D-D-P-D-D-E-K-S-E-V-E-S-Y-D-S-E-L-N-E-I-I-P-E-D-D-F-E-E-V-D-I-N-E-E-D-E-E-D-E-E-D-E-E-P-V-L


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-N-V-V-L-V-G-R-M-T-K-D-A-E-L-R-Y-T-P-S-Q-V-A-V-A-T-F-T-L-A-V-N-R-T-F-K-S-Q-N-G-E-R-E-A-D-F-I-N-C-V-I-W-R-Q-P-A-E-N-L-A-N-W-A-K-K-G-A-L-I-G-I-T-G-R-I-Q-T-R-N-Y-E-N-Q-Q-G-Q-R-V-Y-V-T-E-V-V-A-D-N-F-Q-M-L-E-S-R-A-T-R-E-G-G-S-T-G-S-F-N-G-G-F-N-N-N-T-S-S-S-N-S-Y-S-A-P-A-Q-Q-T-P-N-F-G-R-D-D-S-P-F-G-N-S-N-P-M-D-I-S-D-D-D-L-P-F


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-K-I-S-E-E-E-V-R-H-V-A-K-L-S-K-L-S-F-S-E-S-E-T-T-A-F-A-T-T-L-S-K-I-V-D-M-V-E-L-L-N-E-V-D-T-E-G-V-A-I-T-T-T-M-A-D-K-K-N-V-M-R-Q-D-V-A-E-E-G-T-D-R-A-L-L-F-K-N-V-P-E-K-E-N-H-F-I-K-V-P-A-I-L-Y-D-G-G-D-A


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-N-H-R-I-D-R-V-G-M-E-I-K-R-E-V-N-D-I-L-Q-K-K-V-R-D-P-R-V-Q-G-V-T-I-T-E-V-Q-M-Q-G-D-L-S-L-A-K-V-Y-Y-T-I-M-S-D-L-A-S-D-N-Q-K-A-Q-T-G-L-E-K-A-T-G-T-I-K-R-E-L-G-K-Q-L-T-M-Y-K-I-P-D-L-V-F-E-K-D-N-S-I-A-Y-G-N-K-I-D-Q-L-L-R-E-L-D-N-K-S


### FUNCTION Transfers 2- of the citrate lyase to yield holo-acyl carrier protein ### SEQUENCE -M-C-K-D-T-Y-F-S-G-E-A-I-Q-L-S-D-M-L-R-A-R-E-E-R-A-L-R-Q-L-H-L-L-K-E-Y-P-E-G-S-L-L-S-V-T-M-N-I-P-G-P-I-K-T-S-P-K-L-L-E-A-F-D-I-V-I-K-A-I-Q-T-A-L-A-D-D-K-I-C-Y-Q-L-R-L-L-P-T-T-G-Y-E-Y-Y-L-I-T-S-L-P-S-Q-D-L-K-L-K-M-I-A-L-E-T-D-L-P-I-G-R-L-M-D-L-D-V-L-V-L-S-N-G-R-P-S-P-I-S-R-T-T-L-G-A-P-P-R-Q-C-F-I-C-S-K-E-A-K-V-C-G-R-L-R-K-H-S-V-E-E-M-Q-T-A-I-S-K-L-L-H-S-F-F-N-K-D-N-Q-S-S-S-S-D-K-T-G


### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-D-I-K-Q-T-A-V-A-G-S-L-E-S-S-D-L-M-I-T-V-S-P-N-D-E-Q-T-I-T-I-T-L-D-S-S-V-E-K-Q-F-G-N-H-I-R-Q-L-I-H-Q-T-L-V-N-L-K-V-T-A-A-K-V-E-A-V-D-K-G-A-L-D-C-T-I-Q-A-R-T-I-A-A-V-H-R-A-A-G-V-D-Q-Y-D-W-K-E-I-D-S-W-N-V


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-E-A-I-I-A-K-K-A-E-Q-V-E-L-I-A-E-K-M-K-A-A-A-S-I-V-V-V-D-S-R-G-L-T-V-D-Q-D-T-V-L-R-R-S-L-R-E-S-G-V-E-F-K-V-I-K-N-S-I-L-T-R-A-A-E-K-A-G-L-D-E-L-K-D-V-F-V-G-P-S-A-V-A-F-S-N-E-D-V-I-A-P-A-K-V-I-N-D-F-T-K-T-A-D-A-L-E-I-K-G-G-A-I-E-G-A-V-S-S-K-E-E-I-Q-A-L-A-T-L-P-N-R-Q-G-M-L-S-M-L-L-S-V-L-Q-A-P-V-R-N-V-A-Y-A-V-K-A-V-A-E-N-K-E-G-A-A


### FUNCTION Required for accurate and efficient protein synthesis under certain stress conditions May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes Back-translocation proceeds from a post-translocation ### SEQUENCE -M-K-Q-T-L-D-Y-I-D-D-N-R-V-N-V-I-Y-Q-I-P-L-A-E-I-V-F-D-F-F-D-K-L-K-S-S-T-R-G-Y-A-S-F-D-Y-D-M-S-E-Y-R-R-S-Q-L-V-K-M-D-I-L-L-N-G-D-K-V-D-A-L-S-F-I-V-H-K-E-F-A-Y-E-R-G-K-I-I-V-E-K-L-K-K-I-I-P-R-Q-Q-F-E-V-P-I-Q-A-A-I-G-Q-K-I-V-A-R-S-D-I-K-A-L-R-K-N-V-L-A-K-C-Y-G-G-D-V-S-R-K-R-K-L-L-E-K-Q-K-A-G-K-K-R-M-K-A-I-G-S-V-E-V-P-Q-E-A-F-L-S-V-L-S-M-D-E-D-A-K-K


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-A-E-E-Q-V-L-N-T-H-N-A-S-I-L-L-S-A-A-N-K-S-H-Y-P-Q-D-D-L-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-I-L-G-R-K-N-L-A-R-T-S-S-K-P-G-K-T-Q-L-L-N-F-F-N-I-D-D-K-L-R-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-S-E-R-A-E-W-G-K-M-I-E-E-Y-L-T-S-R-D-N-L-R-A-V-V-S-L-V-D-L-R-H-A-P-S-K-E-D-I-Q-M-Y-D-F-L-K-Y-Y-D-I-P-V-I-V-V-A-T-K-A-D-K-I-P-R-G-K-W-N-K-H-E-S-V-V-K-K-A-L-N-F-D-K-S-D-T-F-I-V-F-S-S-V-E-R-I-G-I-D-D-S-W-D-A-I-L-E-Q-V


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-Y-F-N-V-G-K-I-V-N-T-Q-G-L-Q-G-E-M-R-V-L-S-V-S-D-F-A-E-E-R-F-K-K-G-S-Q-L-A-L-F-D-D-K-D-Q-F-V-Q-E-V-T-I-V-S-H-R-K-Q-K-H-F-D-I-I-K-F-K-D-M-Y-H-I-N-A-I-E-K-Y-K-G-Y-T-L-K-V-S-K-A-N-Q-G-D-L-Q-E-G-E-F-Y-Y-H-Q-I-I-G-M-A-V-Y-E-K-D-R-L-I-G-Y-V-K-E-I-L-Q-P-G-A-N-D-V-W-V-V-K-R-Q-G-K-R-D-L-L-L-P-Y-I-P-P-V-V-L-S-V-D-V-P-N-K-R-V-D-V-E-L-M-E-G-L-D-D-E-D


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-T-K-K-E-Q-A-L-I-E-Q-Y-A-K-S-L-V-E-V-A-S-E-H-H-S-L-D-A-L-Q-A-D-V-L-A-I-L-E-T-F-V-T-T-N-L-D-Q-S-L-S-S-L-A-V-P-H-A-E-K-I-K-L-L-T-L-L-K-G-N-N-S-V-Y-M-N-N-F-L-N-L-I-L-Q-N-E-R-E-A-Y-L-Y-Q-M-L-Q-T-V-L-N-E-I-A-I-V-S-N-Q-Y-D-V-T-V-T-S-S-L-P-L-T-E-E-Q-K-S-R-V-R-A-V-V-A-K-K-F-A-V-T-A-G-R-L-I-E-K-V-D-P-S-L-I-G-G-F-I-I-S-V-N-N-K-V-I-D-T-S-I-R-R-Q-L-Q-A-F-K-M-N-L-K


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-I-T-F-G-E-L-V-G-N-F-I-L-V-T-G-S-V-I-V-L-L-L-L-I-K-K-F-A-W-G-A-I-E-S-I-L-Q-T-R-S-Q-Q-I-S-R-D-I-D-Q-A-E-Q-S-R-L-S-A-Q-Q-L-E-T-K-S-Q-A-N-L-D-A-S-R-S-Q-A-S-K-I-I-S-D-A-K-E-I-G-Q-L-Q-G-D-K-L-V-A-E-A-T-D-E-A-K-R-L-K-E-K-A-L-T-D-I-E-Q-S-K-S-D-A-I-S-A-V-K-T-E-M-S-D-L-T-V-L-L-A-E-K-I-M-G-A-N-L-D-K-T-A-Q-S-Q-L-I-D-S-Y-L-D-D-L-G-E-A


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-G-E-G-H-I-L-A-Q-N-K-K-A-R-L-D-Y-H-I-V-E-T-V-E-A-G-I-V-L-T-G-T-E-I-K-S-V-R-A-A-R-I-Q-L-K-D-G-F-A-Q-I-K-N-G-E-A-W-L-V-N-V-H-I-A-P-F-E-Q-G-N-I-W-N-A-D-P-E-R-T-R-K-L-L-L-K-K-R-E-I-T-H-L-A-N-E-L-K-G-T-G-M-T-L-V-P-L-K-V-Y-L-K-D-G-F-A-K-V-L-I-G-L-A-K-G-K-H-D-Y-D-K-R-E-T-I-K-R-R-D-Q-E-R-D-I-K-K-Q-M-K-H-Y-N-A-R


### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-R-A-I-F-A-G-G-C-F-W-C-M-V-Q-P-F-E-E-Q-A-G-I-L-S-V-R-S-G-Y-T-G-G-H-L-P-N-P-S-Y-E-Q-V-C-A-K-T-T-G-H-T-E-A-V-E-I-I-F-D-P-E-E-I-S-Y-K-E-L-V-E-L-Y-W-A-Q-T-D-P-T-D-A-F-G-Q-F-E-D-R-G-D-N-Y-R-P-V-I-Y-Y-T-T-E-R-Q-K-E-I-A-E-Q-S-K-A-N-L-Q-A-S-G-R-F-D-Q-P-I-V-T-T-I-E-P-A-E-P-F-Y-L-A-E-D-Y-H-Q-G-F-Y-K-K-N-P-K-R-Y-A-Q-S-S-A-I-R-H-Q-F-L-E-E-N-W-S


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-N-A-I-I-E-T-A-K-E-R-F-A-Q-S-H-Q-S-L-S-R-E-Y-A-S-I-R-A-G-R-A-N-A-S-L-L-D-R-I-Q-V-D-Y-Y-G-A-P-T-P-L-N-Q-L-A-S-I-T-V-P-E-A-R-V-L-L-I-S-P-F-D-K-S-S-I-K-D-I-E-R-A-L-N-A-S-D-L-G-I-T-P-A-N-D-G-S-V-I-R-L-V-I-P-A-L-T-E-E-T-R-K-E-L-A-K-E-V-K-K-V-G-E-N-A-K-I-A-I-R-N-I-R-R-D-A-M-D-D-A-K-K-Q-E-K-A-K-E-I-T-E-D-E-L-K-T-L-E-K-D-I-Q-K-A-T-D-D-A-I-K-E-I-D-R-M-T-A-E-K-E-K-E-L-L-S-G


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-K-M-I-V-G-L-G-N-P-G-S-K-Y-E-K-T-K-H-N-I-G-F-M-A-I-D-N-I-V-K-N-L-D-V-T-F-T-D-D-K-N-F-K-A-Q-I-G-S-T-F-I-N-H-E-K-V-Y-F-V-K-P-T-T-F-M-N-N-S-G-I-A-V-K-A-L-L-T-Y-Y-N-I-D-I-T-D-L-I-V-I-Y-D-D-L-D-M-E-V-S-K-L-R-L-R-S-K-G-S-A-G-G-H-N-G-I-K-S-I-I-A-H-I-G-T-Q-E-F-N-R-I-K-V-G-I-G-R-P-L-K-G-M-T-V-I-S-H-V-M-G-Q-F-N-T-E-D-N-I-A-I-S-L-T-L-D-R-V-V-N-A-V-K-F-Y-L-Q-E-N-D-F-E-K-T-M-Q-K-F-N-G


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-I-W-H-W-L-I-V-L-V-I-V-L-L-V-F-G-T-K-R-L-T-S-G-A-K-D-L-G-S-A-V-K-E-F-K-K-G-M-H-D-D-D-K-P-A-G-K-L-G-D-D-S-R-S-A-E-Q-A-R-E-A-Q-A-E-R-D-R-D-A-R


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-S-E-L-A-L-I-A-V-V-A-L-V-V-L-G-P-E-R-L-P-K-A-A-R-F-A-G-L-W-V-R-R-A-R-M-Q-W-D-S-V-K-Q-E-L-E-R-E-L-E-A-E-E-L-K-R-S-L-Q-D-V-Q-A-S-L-R-E-A-E-G-Q-L-R-N-T-Q-Q-Q-V-E-D-G-A-R-G-L-H-D-Q-A-R-E-L-H-D-E-V-G-R-D-I-D-I-R-T-S-A-T-P-L-A-A-P-L-E-L-Q-A-D-A-P-V-V-L-E-P-G-S-A-Q-P-H-T-P-V-P-A-P-A-P-V-V-A-Q-A-Q-P-M-A-P-A-P-K-Q-T-L-V-P-A-P-H-G-S-L-T-S-T-Q-V-T-T-H-A-P-T-A-S-A-T-A-S-S-T-S-P-Q-E-K-T-P


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-S-P-L-S-I-V-L-L-G-F-A-M-S-T-D-A-F-A-A-A-I-G-K-G-A-A-M-R-R-P-R-W-R-D-A-V-R-A-G-L-V-F-G-C-I-E-A-I-T-P-V-I-G-W-M-L-G-R-A-A-S-D-Y-L-A-A-F-D-H-W-I-A-F-G-L-L-G-A-L-G-A-H-M-I-V-A-G-L-R-N-E-S-E-V-D-E-A-L-R-D-T-P-K-R-Y-G-L-L-A-L-A-A-T-G-F-A-T-S-I-D-A-M-A-V-G-V-S-L-A-F-L-D-V-H-I-G-V-V-A-A-V-V-G-L-C-T-L-S-M-V-T-A-G-V-M-L-G-R-A-L-G-A-L-I-G-K-R-A-E-I-L-G-G-V-I-L-I-L-I-G-S-T-I-L-Y-E-H-L-S-G-A-A


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-Q-S-L-Q-V-K-L-L-D-P-R-F-G-D-L-W-P-L-P-A-Y-A-T-E-A-S-A-G-M-D-L-R-A-A-L-E-A-P-M-T-L-E-P-G-D-A-A-L-I-P-S-G-I-A-I-H-L-D-D-P-Q-V-C-A-V-I-L-P-R-S-G-L-G-H-R-H-G-I-V-L-G-N-G-T-G-L-I-D-A-D-Y-Q-G-P-L-L-I-S-T-W-N-R-G-R-E-A-F-T-I-E-P-G-D-R-I-A-Q-L-V-I-L-P-I-V-R-V-S-L-Q-V-V-D-T-F-V-D-S-A-R-G-A-G-G-F-G-H-T-G-V-R


### FUNCTION Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'--3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism ### SEQUENCE -M-E-T-L-R-Y-R-F-D-G-R-N-G-A-R-T-G-L-D-H-A-L-V-G-V-V-A-S-G-N-L-E-V-L-V-E-R-V-P-L-G-G-A-M-E-I-E-I-V-T-A-A-R-G-F-G-E-I-W-Q-A-V-L-D-D-F-A-A-R-H-S-L-Q-D-V-R-I-S-I-N-D-V-G-A-T-P-A-V-V-S-L-R-L-E-Q-A-I-D-V-L-Q-G-A-D-A


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-G-M-V-S-E-F-K-Q-F-A-M-R-G-N-V-I-D-L-A-V-G-V-V-I-G-A-A-F-G-K-I-V-T-A-L-V-E-K-I-I-M-P-P-I-G-W-A-I-G-N-V-D-F-S-R-L-A-W-V-L-K-P-A-G-V-D-A-T-G-K-E-I-P-A-V-V-I-G-Y-G-D-F-I-N-T-V-V-Q-F-V-I-I-A-F-A-I-F-L-V-V-K-L-I-N-R-L-S-Q-R-K-P-D-A-P-K-G-P-S-E-E-V-L-L-L-R-E-I-R-D-S-L-K-N-D-T-L-K-N-P-T-V-P


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-L-R-G-I-L-A-Y-K-Q-P-P-W-L-V-I-D-V-G-G-V-G-Y-E-L-E-A-P-M-S-T-F-Y-D-L-P-D-V-G-R-D-V-I-L-F-T-H-Y-A-Q-K-E-D-S-V-S-L-Y-G-F-L-R-E-G-E-R-R-L-F-R-D-V-Q-K-V-T-G-I-G-A-K-I-A-L-A-V-L-S-G-V-T-V-D-E-F-A-R-L-I-T-S-G-D-I-T-A-L-T-R-I-P-G-I-G-K-K-T-A-E-R-M-V-V-E-L-R-D-R-A-A-D-F-S-S-G-A-P-I-T-G-Q-L-G-P-D-A-V-S-E-A-T-V-A-L-Q-Q-L-G-Y-K-P-A-E-A-A-R-M-A-R-E-A-G-A-E-G-D-E-V-A-T-V-I-R-K-A-L-Q-A-A-L-R


### FUNCTION Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone  biosynthetic pathway ### SEQUENCE -M-S-T-I-S-R-D-S-C-P-A-L-R-A-G-V-R-L-Q-H-D-R-A-R-D-Q-W-V-L-L-A-P-E-R-V-V-E-L-D-D-I-A-L-V-V-A-Q-R-Y-D-G-T-Q-S-L-A-Q-I-A-Q-T-L-A-A-E-F-D-A-D-A-S-E-I-E-T-D-V-I-E-L-T-T-T-L-H-Q-K-R-L-L-R-L


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-E-I-P-G-D-L-K-F-L-K-S-H-E-W-A-R-V-E-G-N-G-R-V-T-V-G-I-S-D-H-A-Q-G-L-L-G-D-L-V-Y-V-E-L-P-A-V-G-D-T-V-Q-A-G-N-G-A-A-V-V-E-S-V-K-A-A-S-D-V-Y-S-P-V-T-G-T-V-V-E-V-N-A-S-L-S-D-K-P-E-T-I-N-E-D-A-Y-G-E-G-W-I-F-V-V-E-I-D-D-K-E-Q-L-N-E-L-L-A-P-D-D-Y-A-E-L-L-E-D-D-A-H


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-E-A-G-A-I-R-P-D-A-T-V-L-G-F-D-V-G-S-R-R-I-G-V-A-V-G-T-A-L-G-A-G-A-R-A-V-A-V-I-N-V-H-A-N-G-P-D-W-V-A-L-D-R-V-H-K-E-W-R-P-A-G-L-V-V-G-D-P-L-T-L-D-D-K-D-Q-P-A-R-K-R-A-H-A-F-A-R-E-L-R-E-R-Y-A-L-P-V-V-L-I-D-E-R-S-S-S-V-E-A-A-Q-R-F-A-R-E-R-A-D-G-R-K-R-R-R-D-A-D-T-L-D-A-M-A-A-A-V-I-V-E-R-W-L-S-A-P-E-Q-A-T-L-L-P


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-R-G-I-N-K-V-I-L-V-G-N-L-G-N-D-P-D-T-K-Y-T-Q-A-G-M-A-I-T-R-V-S-L-A-T-T-S-M-R-K-D-R-E-G-N-N-Q-E-R-T-E-W-H-R-V-V-F-F-G-K-L-G-E-I-A-G-E-Y-L-R-K-G-S-Q-V-Y-V-E-G-E-L-R-Y-D-K-Y-T-G-Q-D-G-V-E-K-Y-S-T-D-I-V-A-N-E-M-Q-M-L-G-G-R-G-E-G-G-G-G-G-G-M-G-G-D-R-P-Q-R-T-Q-A-P-R-Q-Q-Q-G-G-G-G-G-G-G-G-Q-D-Y-A-P-R-R-Q-Q-P-A-Q-Q-Q-S-A-P-P-M-D-D-F-A-D-D-D-I-P-F


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-K-C-R-L-I-A-T-G-E-R-A-P-A-W-V-A-Q-G-F-A-E-Y-Q-K-R-L-S-H-W-M-P-L-E-L-V-E-I-E-P-G-L-R-G-K-G-R-D-A-Q-R-A-I-D-D-E-G-R-R-V-L-A-A-L-P-K-N-A-H-V-V-A-L-D-V-P-G-R-P-L-S-S-E-Q-L-A-Q-R-M-E-H-W-R-G-Q-G-R-D-L-A-F-L-I-G-G-P-E-G-H-A-A-D-V-V-K-S-A-N-E-S-W-S-I-G-P-L-T-L-P-H-M-L-V-R-L-I-V-A-E-Q-L-Y-R-A-A-A-M-L-A-N-H-P-Y-H-R-A


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-K-K-S-L-N-E-S-S-P-V-A-R-F-E-Q-S-L-E-E-L-E-Q-L-V-Q-K-M-E-V-G-E-M-S-L-E-Q-S-L-T-A-Y-E-R-G-I-G-L-Y-R-D-C-Q-Q-A-L-E-Q-A-E-L-R-V-R-L-V-T-D-P-A-R-P-E-Q-A-E-A-F-E-P-P-S-L-D-G-G


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-S-R-W-R-P-P-A-E-K-S-T-A-L-I-T-P-E-G-H-A-R-L-K-A-E-L-D-E-L-W-R-L-R-R-P-E-V-V-R-A-L-A-A-A-A-A-E-G-D-R-S-E-N-A-E-Y-T-Y-R-K-K-Q-L-G-E-I-D-R-R-V-R-Y-L-S-K-R-L-E-A-L-R-V-V-D-T-A-P-T-D-P-Q-A-V-F-F-G-A-Q-V-E-L-E-D-A-D-S-G-E-L-L-R-Y-R-I-V-G-P-D-E-T-D-A-G-R-G-W-I-S-I-D-S-P-L-A-R-A-L-L-K-K-R-V-D-D-E-F-E-A-Q-L-P-S-G-K-H-T-F-V-V-V-V-V-E-Y-A-A-T


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-E-K-A-T-E-I-A-N-L-L-G-P-T-V-E-S-L-G-L-E-L-L-G-V-E-Y-L-P-A-P-G-G-A-T-L-R-L-Y-I-D-V-P-L-A-E-Q-P-D-R-I-I-N-V-D-D-C-E-R-V-S-R-E-V-S-A-Q-L-D-V-E-D-P-I-S-G-N-Y-T-L-E-V-S-S-P-G-V-D-R-P-L-F-T-L-D-Q-F-A-R-H-V-G-E-S-A-K-I-V-L-K-L-A-Q-D-G-R-R-R-F-Q-G-Q-I-V-R-I-D-T-E-A-A-A-V-V-F-S-V-D-G-K-D-V-Q-I-G-F-D-N-I-D-K-A-R-I-L-P-D-W-V-A-L-G-L-A-P-Q-K-P-N-K-P-G-P-K-K-P-G-H-D-K-K-K-P-S-N-E-P-A-A-G-K-P-R-A-E


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-T-M-P-T-K-S-F-H-R-T-D-R-V-S-A-Q-V-R-R-D-L-G-T-I-V-H-A-A-V-R-D-H-G-L-P-S-V-S-V-S-D-V-E-I-S-R-D-L-A-H-A-K-V-F-V-T-A-L-Q-Q-E-R-S-A-E-A-V-K-G-L-K-E-I-A-G-Q-L-R-T-Q-L-A-R-A-M-K-L-R-H-V-P-E-L-H-F-H-Y-D-D-S-V-D-R-G-E-R-I-D-N-L-L-R-D-L-D-D-I-G-P-E-A-A-P-D-A-Q-D-A-E-P-R


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-V-D-T-Q-K-V-I-E-D-N-K-R-S-A-Q-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-R-I-E-L-L-T-G-H-F-K-T-H-K-K-D-H-H-S-R-R-G-L-L-Q-M-V-N-R-R-R-S-L-L-D-Y-L-K-K-K-D-G-E-R-Y-K-S-L-I-E-K-L-G-L-R-R


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-P-L-G-D-C-N-I-S-T-P-D-N-K-Q-N-R-K-N-Q-E-I-R-V-P-R-V-R-V-I-G-S-D-G-E-M-V-G-V-L-S-R-D-E-A-L-A-K-A-E-E-E-G-L-D-L-V-E-I-Q-P-Q-A-D-P-P-V-C-K-I-M-D-F-G-K-F-K-F-E-Q-Q-K-K-A-N-E-A-K-K-K-T-K-Q-V-E-I-K-E-L-K-F-R-P-V-T-D-E-G-D-Y-Q-I-K-L-R-N-M-R-R-F-L-E-E-G-D-K-V-K-V-N-I-R-F-R-G-R-E-M-S-H-Q-E-L-G-R-E-M-A-A-R-I-E-A-D-L-G-E-D-I-V-I-E-S-R-P-R-L-E-G-R-Q-M-V-M-M-I-A-P-K-K-K-I


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-Q-A-R-R-R-H-K-K-I-L-T-L-A-K-G-Y-Y-N-A-R-R-K-V-F-R-V-A-K-Q-A-V-I-K-A-Q-Q-Y-A-Y-I-G-R-K-Q-K-K-R-N-F-R-S-L-W-I-T-R-I-N-A-A-A-R-I-N-G-L-S-Y-S-R-F-M-N-G-M-L-K-A-G-I-T-L-D-R-K-V-L-A-D-I-A-V-H-D-A-A-G-F-A-A-L-A-E-K-A-K-G-A-L-A-A


### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-V-F-C-Q-Y-Q-Q-C-D-T-E-G-L-D-F-A-P-Y-P-G-E-L-G-Q-R-I-F-A-Q-I-G-K-A-G-W-Q-A-W-L-A-H-Q-T-M-L-I-N-E-N-R-L-S-P-R-D-P-K-H-R-A-F-L-E-A-E-L-Q-K-F-L-F-E-R-N-A-D-K-P-E-G-Y-V-D-P-L-G-E-E


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-K-G-P-V-R-L-D-V-G-V-S-Y-A-L-P-R-T-G-L-P-S-S-V-S-F-R-K-W-V-A-A-A-L-K-G-R-I-R-E-A-D-L-A-V-R-V-V-D-E-K-E-G-C-S-L-N-H-H-Y-R-G-K-D-Y-A-T-N-V-L-S-F-P-A-E-M-P-Q-G-L-P-K-G-V-K-M-P-L-L-G-D-L-V-I-C-A-P-V-V-A-R-E-A-A-E-Q-G-K-S-L-S-A-H-Y-A-H-L-T-V-H-G-T-L-H-L-L-G-W-D-H-E-D-D-K-E-A-D-A-M-E-Q-L-E-R-E-I-L-A-E-L-G-I-D-D-P-Y-A-G-E-R


### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-T-V-G-M-N-D-V-K-N-G-M-K-I-L-V-N-N-E-P-A-V-I-T-E-T-E-Y-V-K-P-G-K-G-Q-A-F-T-R-M-K-Y-R-F-I-K-S-G-R-V-V-E-M-T-M-K-A-T-D-D-V-E-V-A-D-V-V-D-T-D-M-R-Y-L-Y-T-D-G-E-Y-W-H-F-M-D-P-E-S-F-E-Q-V-Q-A-D-K-A-G-M-G-G-A-E-K-W-L-K-G-E-E-D-C-I-V-T-L-W-N-G-A-P-I-W-V-Q-P-P-N-F-V-E-L-K-I-T-E-T-D-P-G-V-R-G-D-T-S-G-G-G-G-K-P-A-T-L-E-T-G-A-V-V-R-V-P-L-F-V-N-Q-D-E-V-I-K-V-D-T-R-S-G-E-Y-S-A-R-V-K


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-I-L-A-R-R-Q-A-H-L-K-S-D-D-V-D-L-A-V-K-S-L-L-E-M-M-G-Q-A-L-S-D-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-P-P-R-L-G-R-N-P-K-T-G-E-S-V-A-L-P-G-K-H-V-P-H-F-K-P-G-K-E-L-R-E-R-V-S-S-V-V-P-V-D-M-V-D-A-A-D


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-D-N-V-A-G-N-D-R-L-I-W-I-D-L-E-M-T-G-L-D-T-D-R-D-S-I-I-E-I-A-T-I-V-T-D-A-Q-L-N-V-L-A-E-G-P-E-L-A-I-A-H-S-L-E-T-L-E-A-M-D-E-W-N-R-N-Q-H-R-R-S-G-L-W-Q-R-V-L-D-S-Q-V-T-H-A-Q-A-E-A-Q-T-V-A-F-L-S-E-W-I-R-A-G-A-S-P-M-C-G-N-S-I-C-Q-D-R-R-F-L-H-R-Q-M-S-R-L-E-R-Y-F-H-Y-R-N-L-D-V-S-T-I-K-E-L-A-R-R-W-A-P-A-V-A-S-G-F-A-K-S-S-A-H-T-A-L-S-D-V-R-D-S-I-D-E-L-R-H-Y-R-Q-F-M-G-T-L-G-G-D-N-G-G-G-V-Q-N


### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase  of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-E-K-E-M-D-E-D-T-L-L-K-K-L-R-W-R-C-R-R-G-M-R-E-L-D-Q-L-F-G-R-Y-L-D-R-R-W-A-Q-A-P-A-A-E-R-A-V-F-L-Q-L-L-D-C-E-D-D-K-L-W-R-W-F-M-G-Y-E-A-C-P-D-A-D-N-A-A-L-I-A-D-I-R-A-M-P-A


### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-Q-I-S-D-K-A-Q-T-Y-F-R-K-L-I-E-R-E-G-V-P-G-M-G-V-R-L-S-A-V-D-A-G-T-P-R-A-D-A-K-L-E-F-A-E-P-A-D-L-S-G-D-E-W-A-I-D-C-D-G-F-T-L-Y-V-V-A-A-S-V-P-W-M-D-G-A-E-I-D-Y-V-T-Q-S-T-G-N-Q-Q-L-T-I-K-A-P-K-I-K-G-E-A-P-A-E-S-A-S-M-V-E-R-V-R-W-V-V-E-N-E-I-N-P-Q-L-A-S-H-G-G-R-V-A-V-Q-E-V-S-A-E-G-V-V-L-L-R-F-G-G-G-C-H-G-C-G-M-A-D-V-T-L-K-Q-G-I-E-K-T-L-M-G-R-L-P-G-V-I-A-V-R-D-A-T-D-H-A-T-G-D-A-P-Y-I-P-R-D-S-A-A


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-S-I-E-F-E-G-S-V-S-E-T-L-P-N-T-T-F-R-V-K-L-E-N-G-Y-E-I-I-A-H-I-S-G-R-M-R-K-N-Y-I-R-I-L-T-G-D-R-V-K-V-E-M-T-P-Y-D-L-T-K-G-R-I-T-Y-R-M-K


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-P-R-K-T-S-H-E-H-D-H-G-L-V-V-E-T-S-K-P-E-V-A-P-P-P-R-Y-Q-V-L-L-L-N-D-D-Y-T-P-M-D-F-V-V-T-V-L-Q-Q-F-F-N-L-E-L-E-R-A-T-Q-V-M-L-H-V-H-T-R-G-R-G-V-C-G-V-Y-S-R-E-V-A-E-S-K-V-A-Q-V-N-E-F-S-R-M-N-Q-H-P-L-L-C-T-M-E-Q-A


### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-S-T-A-V-Q-V-D-D-V-M-R-Y-R-D-S-R-F-Q-T-I-A-A-K-L-L-P-T-Q-Y-L-V-V-D-D-D-T-A-L-T-T-T-L-G-S-C-V-A-A-C-L-R-D-P-V-L-K-I-G-G-M-N-H-F-L-L-P-E-G-Q-V-G-D-G-A-P-A-R-Y-G-S-Y-A-M-E-L-L-I-N-D-M-L-K-R-G-A-H-R-K-R-I-E-A-K-V-F-G-G-A-N-V-L-K-G-F-T-S-N-P-V-G-T-R-N-A-E-F-V-R-Q-Y-L-Q-A-E-H-I-P-I-I-A-E-D-L-C-G-I-H-P-R-K-V-W-F-F-P-T-T-G-R-V-V-V-Q-R-L-P-H-A-H-E-A-E-V-A-A-A-E-S-A-V-R-A-R-L-S-K-A-P-V-T-G-G-V-E-L-F-E


### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-M-I-G-D-L-V-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-I-D-A-P-K-D-V-A-V-H-R-E-E-I-Y-Q-R-I-Q-R-G-D-E-P-V-A-S-G-A-H-H-N-D-D-C-S-D


### FUNCTION Modulates RecA activity ### SEQUENCE -M-S-E-Q-A-P-A-P-K-R-G-R-R-F-K-E-Q-T-P-V-Q-R-A-L-G-L-L-V-R-R-E-H-S-K-K-E-L-N-R-K-L-Q-A-R-G-I-E-P-E-A-A-Q-A-A-V-E-R-L-A-G-E-G-W-Q-D-D-V-R-F-A-A-S-V-V-R-N-R-A-S-S-G-Y-G-P-L-H-I-R-A-E-L-G-T-H-G-L-D-S-D-A-V-S-A-A-M-A-T-F-E-G-D-W-T-E-N-A-L-D-L-I-R-R-R-F-G-E-D-G-P-V-D-L-A-Q-R-R-K-A-A-D-L-L-A-R-R-G-F-D-G-N-S-I-R-L-A-T-R-F-D-L-E-D


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-V-P-V-S-V-Y-L-V-N-G-I-K-L-Q-G-T-I-E-S-F-D-Q-F-V-V-L-L-R-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-N-V-R-V-G-P-G-G-G-Y-V-Q-S-N-E-N-N-Q-A-E-D-D-D-V-E-Q


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-D-L-I-L-L-Q-K-V-T-N-L-G-N-L-G-D-K-V-S-V-K-P-G-Y-G-R-N-F-L-V-P-Q-G-K-A-V-P-A-T-A-A-N-V-E-A-F-E-T-K-R-A-E-Y-E-A-K-A-N-T-I-L-A-D-A-Q-S-R-A-T-K-F-E-G-A-S-V-T-I-G-A-H-A-S-T-E-G-K-L-Y-G-S-V-G-P-R-D-I-A-E-A-F-T-A-A-G-L-P-L-E-K-S-E-V-I-L-G-E-G-A-F-R-N-V-G-E-Y-D-V-V-L-H-L-H-A-D-V-E-T-T-V-K-V-I-V-E-S-D-A


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-K-F-F-R-R-R-K-F-C-K-F-T-A-E-G-V-K-E-I-D-Y-K-D-L-N-T-L-R-Q-Y-L-T-E-N-G-K-I-V-P-S-R-V-T-G-T-K-S-K-Y-Q-R-Q-L-A-T-A-V-K-R-S-R-F-L-A-L-I-P-Y-T-D-N-H-D-V


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-R-H-Y-E-V-V-F-L-V-H-P-D-Q-S-E-Q-V-P-A-M-I-E-R-Y-K-S-L-I-E-G-G-N-G-T-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-Q-N-L-V-K-A-H-Y-V-L-L-N-I-E-V-D-Q-A-V-L-S-E-L-V-E-S-F-R-F-N-D-A-V-L-R-H-L-V-I-K-R-D-G-P-D-T-E-Q-S-L-I-M-K-S-K-D-E-K-G-D-K-P-E-R-S-E-R-R-R-R-D-D-E-E-G-D-A-A-P-A-A-T-D-T-D-G-D-N-A-E-A-A


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-Q-D-H-P-E-F-D-S-E-D-L-S-Q-N-P-P-E-T-D-P-L-K-A-E-I-E-S-L-R-S-E-I-A-L-V-K-A-D-A-L-R-E-R-A-D-L-E-N-Q-R-K-R-I-A-R-D-V-E-N-A-R-K-F-A-N-E-K-L-L-G-E-L-L-P-V-F-D-S-L-D-A-G-L-T-A-A-G-T-E-P-S-P-L-R-D-G-L-D-L-T-Y-K-Q-L-L-K-V-A-A-D-N-G-L-T-L-L-D-P-V-G-Q-P-F-N-P-D-Q-H-Q-A-I-S-Q-G-E-A-E-G-I-A-P-G-H-V-V-Q-V-F-Q-K-G-Y-L-L-N-E-R-L-L-R-P-A-L-V-V-V-A-K-H-D


### FUNCTION Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ### SEQUENCE -M-R-N-L-L-L-V-A-A-V-A-L-S-T-A-G-C-G-I-I-Y-K-Q-P-I-Y-Q-G-N-L-I-K-Q-T-A-V-E-Q-L-Q-V-G-Q-S-K-Q-Q-V-S-A-L-L-G-T-P-S-I-P-D-P-F-H-A-Q-R-W-D-Y-T-S-T-Q-R-V-D-R-L-A-R-T-D-V-K-N-F-T-V-F-F-E-N-E-Q-V-V-R-W-E-G-D-Y-F-P-A-Q-D-E-Q-L-A-K-S-A-P-K-Q-F-G-R-N-L-A-R-D-K-K-K-Q-R-G-R


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-K-K-P-A-K-D-K-A-K-S-A-T-A-T-K-T-I-A-L-N-K-R-A-R-H-E-Y-H-L-E-E-R-Y-E-A-G-L-A-L-Q-G-W-E-V-K-A-I-R-A-G-R-A-N-I-V-D-G-Y-A-Y-V-R-S-G-E-I-Y-L-I-G-A-Q-I-T-P-L-I-Q-A-S-T-H-V-I-P-V-E-R-R-D-R-K-L-L-L-H-R-A-E-I-D-K-V-L-T-R-V-E-R-E-G-Y-T-L-V-P-T-A-L-Y-W-S-S-N-K-V-K-L-E-I-A-L-A-K-G-K-Q-S-H-D-K-R-D-A-A-K-E-R-D-W-Q-R-D-K-Q-R-V-M-R-R-H-N-R-D-A


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-N-Q-I-K-Q-D-A-Q-T-R-M-T-K-S-I-D-A-L-R-H-S-L-T-T-V-R-T-G-R-A-S-P-A-L-L-D-N-I-K-V-K-A-Y-G-T-D-T-P-L-N-Q-V-A-S-I-S-V-S-E-G-R-S-L-V-I-S-L-F-D-K-G-M-I-K-D-V-E-K-A-I-Y-A-S-D-L-G-L-T-P-T-V-V-G-T-V-I-R-L-N-L-P-P-L-T-E-E-R-R-K-E-L-S-K-S-V-H-G-E-G-E-D-A-K-V-A-I-R-N-I-R-R-D-A-N-Q-Q-V-K-D-L-L-K-D-K-Q-V-T-E-D-E-A-R-G-A-E-D-D-I-Q-K-L-T-D-K-A-I-K-D-V-D-E-V-V-K-G-K-E-Q-E-L-M-T-V


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-K-L-N-K-T-I-L-A-D-F-E-A-A-Q-I-Q-R-Q-L-P-E-F-N-Q-G-D-T-V-V-V-N-V-K-V-K-E-G-N-R-E-R-V-Q-A-Y-E-G-V-V-I-G-T-K-N-A-G-L-N-S-A-F-T-V-R-K-I-S-H-G-F-G-V-E-R-V-F-Q-T-H-S-A-I-I-D-S-V-E-V-K-R-R-G-K-V-R-A-G-K-L-Y-Y-L-R-G-L-E-G-K-A-A-R-I-K-E-D-L-A-A-A-A-Q-A-K-A-A-R-Q-A-A-A-K-A-E


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-P-T-E-R-R-I-L-L-G-R-I-V-G-A-F-G-V-K-G-E-L-K-L-E-S-W-T-E-P-R-S-A-I-F-R-Y-Q-P-W-I-V-R-T-P-S-G-Q-E-S-V-L-S-G-V-R-G-R-D-Q-G-K-N-L-I-A-V-F-P-D-I-T-D-R-D-T-V-E-A-M-H-G-T-E-I-Y-V-A-R-S-A-L-P-P-P-K-P-D-E-Y-Y-W-V-D-L-E-G-L-Q-V-E-T-V-E-G-V-K-L-G-T-V-S-H-L-F-S-T-G-S-N-D-V-V-V-V-R-G-D-R-E-R-M-I-P-F-V-L-P-E-Y-V-K-S-V-D-F-E-A-N-L-I-V-V-D-W-D-P-D-F


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-R-A-K-Q-T-V-V-R-N-E-R-N-T-G-Q-R-S-M-L-R-T-A-V-K-K-V-I-K-A-L-D-A-N-D-A-A-G-A-E-A-A-F-A-V-A-Q-P-I-L-D-R-F-S-A-R-G-L-I-H-K-N-K-A-A-R-H-K-S-R-L-T-A-R-I-K-A-I-K-A-A


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-L-V-T-G-G-K-Q-Y-R-V-A-Q-G-E-T-L-R-V-E-K-L-E-V-E-A-G-N-E-I-K-F-D-T-I-L-M-L-G-D-S-D-G-I-K-L-G-D-A-L-K-G-A-S-V-T-A-K-V-V-A-H-G-R-A-D-K-V-R-I-I-K-F-R-R-R-K-H-H-M-K-R-Q-G-H-R-Q-Y-Y-T-E-I-E-I-T-G-I-A-G-G-D-K-K


### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-G-L-L-D-F-L-K-S-K-K-N-T-A-E-T-A-K-N-R-L-Q-I-I-I-A-Q-E-R-N-H-R-G-G-P-D-Y-L-P-L-M-Q-R-E-L-L-E-V-I-K-K-Y-V-N-I-D-A-D-A-V-R-V-D-L-V-K-D-G-E-H-D-V-L-D-I-T-V-A-L-P-E-D-G-D-K


### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-M-P-R-L-I-L-A-S-T-S-A-Y-R-R-E-L-L-G-R-L-H-L-D-F-D-T-A-R-P-E-V-D-E-H-A-L-P-G-E-T-P-Q-A-L-A-T-R-L-A-G-E-K-A-R-A-V-A-V-R-F-P-E-A-W-V-I-G-S-D-Q-V-A-D-L-D-G-Q-A-L-G-K-P-G-T-L-E-Q-A-R-A-Q-L-T-R-M-S-G-R-M-V-R-F-Q-T-A-V-S-L-I-G-P-D-G-F-A-A-Q-A-L-D-L-T-D-V-Q-V-R-P-L-Q-P-Q-E-I-E-R-Y-L-A-A-E-P-A-L-E-C-A-G-S-F-K-C-E-G-L-G-I-T-L-F-D-A-I-R-S-N-D-P-T-A-L-V-G-L-P-L-I-A-V-A-R-L-L-R-Q-A-G-F-S-L-P


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-S-L-L-E-Q-L-I-E-A-F-R-V-L-P-G-V-G-Q-K-S-A-Q-R-M-A-Y-H-V-L-E-R-E-R-E-G-G-R-R-L-A-A-A-L-A-N-A-V-E-K-V-G-H-C-V-Q-C-R-D-F-T-E-S-E-V-C-A-I-C-A-N-S-G-R-D-R-Q-Q-L-C-V-V-E-S-P-A-D-R-L-A-I-E-H-A-T-G-Y-R-G-V-Y-F-I-L-Q-G-R-L-S-P-L-D-G-I-G-P-R-E-L-G-L-D-R-L-A-E-R-L-A-A-G-E-V-T-E-M-I-I-A-T-N-A-T-V-E-G-E-A-T-A-H-Y-L-A-Q-L-A-R-Q-H-S-V-R-P-S-R-L-A-Q-G-M-P-L-G-G-E-L-E-Y-V-D-R-G-T-L-S-H-A-F-G-T-R-S-E-V-L


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-R-G-N-I-A-Q-L-M-Q-Q-A-Q-K-M-Q-E-N-L-Q-R-A-Q-E-E-L-A-K-L-E-V-T-G-S-A-G-G-G-M-V-S-V-T-L-T-G-A-K-E-C-R-K-V-R-I-D-P-S-I-L-S-D-Q-E-M-A-E-D-L-I-A-A-A-F-N-D-A-S-N-K-I-D-A-E-S-K-E-R-M-G-S-A-T-A-G-M-Q-L-P-P-G-M-K-L-P-F


### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-N-P-F-R-W-G-F-R-A-Q-F-L-L-G-F-L-A-C-A-G-L-L-A-Y-A-I-Y-V-Q-L-H-L-G-L-E-P-C-P-L-C-I-F-Q-R-I-A-F-A-T-L-A-L-L-F-L-L-G-A-L-H-G-P-R-G-A-G-G-R-K-A-Y-G-V-L-A-F-I-A-A-G-V-G-M-G-I-A-A-R-H-V-W-V-Q-I-R-P-K-D-M-M-S-S-C-G-P-P-L-S-F-L-S-E-T-M-G-P-F-E-V-F-R-T-V-L-T-G-T-G-D-C-G-N-I-D-W-R-F-L-G-L-S-M-P-M-W-S-M-V-W-F-V-G-L-A-L-W-A-L-Y-A-G-F-K-H-R-G-P-R-K-L-F


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-M-H-L-N-D-L-K-P-A-D-G-A-R-T-E-R-T-R-V-G-R-G-I-G-S-G-L-G-K-T-C-G-R-G-H-K-G-S-F-A-R-K-G-G-G-K-I-K-A-G-F-E-G-G-Q-T-P-M-Q-R-R-L-P-K-I-G-F-R-S-K-M-A-R-D-S-A-E-V-L-S-Y-Q-L-D-K-L-E-A-G-E-I-D-F-A-A-L-R-A-A-N-L-V-P-S-R-A-K-K-A-K-I-V-L-K-G-E-L-S-K-K-F-V-L-K-G-V-A-A-T-A-G-A-K-A-A-I-E-A-A-G-G-S-V-E-E


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-I-N-K-N-I-A-R-L-R-R-A-K-S-T-R-A-H-I-R-E-L-G-V-A-R-L-S-V-L-R-T-G-Q-H-L-Y-A-Q-V-F-T-A-D-G-S-K-V-I-A-A-A-N-T-L-Q-A-D-V-K-D-G-L-K-N-G-K-N-S-D-A-A-V-K-V-G-K-L-I-A-E-R-A-K-A-A-G-I-E-K-V-A-F-D-R-S-G-Y-R-Y-H-G-R-I-K-A-L-A-D-A-A-R-E-G-G-L-Q-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-K-P-V-S-L-P-K-G-V-E-L-N-V-Q-P-E-L-I-S-V-K-G-P-K-G-T-L-T-L-Q-K-P-V-G-V-E-I-A-I-D-G-D-V-A-T-L-S-A-N-D-P-S-Q-I-A-I-T-G-T-V-R-A-I-L-A-N-M-I-K-G-V-S-E-G-F-E-R-K-L-E-L-V-G-V-G-Y-R-A-A-M-Q-G-K-D-L-S-L-A-L-G-F-S-H-P-L-V-F-V-A-P-E-G-I-T-L-S-T-P-T-Q-T-E-I-L-V-Q-G-A-D-K-Q-R-V-G-E-V-A-A-K-I-R-G-F-R-P-P-E-P-Y-K-G-K-G-V-K-Y-A-G-E-V-I-I-R-K-E-A-K-K-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-T-D-P-I-A-D-L-L-V-R-I-K-N-A-A-A-V-G-K-Q-T-V-K-L-P-S-S-K-I-K-V-A-I-A-Q-V-L-K-D-E-G-Y-I-T-D-L-R-V-T-A-T-E-N-N-K-S-E-L-E-I-V-L-K-Y-F-E-G-R-P-V-I-E-T-L-K-R-F-S-R-S-G-L-R-Q-Y-R-G-K-T-E-L-P-K-V-L-G-G-L-G-I-A-I-I-S-T-S-K-G-I-M-T-D-A-Q-A-R-E-A-G-V-G-G-E-V-L-C-F-V-A


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-T-R-L-E-K-F-Y-K-E-N-V-V-P-A-L-M-K-E-F-G-Y-T-N-P-M-E-V-P-K-L-V-K-V-T-L-N-M-G-V-G-E-A-A-T-N-K-K-I-L-E-N-A-V-A-D-M-S-K-I-S-G-Q-K-P-V-V-T-K-S-R-V-S-V-A-S-F-K-I-R-D-G-W-P-I-G-C-K-T-T-L-R-R-A-K-M-Y-E-F-L-D-R-L-I-N-I-S-L-P-R-V-R-D-F-R-G-V-S-G-R-S-F-D-G-R-G-N-F-N-M-G-V-K-E-Q-I-I-F-P-E-I-D-F-D-A-V-D-A-I-R-G-M-D-I-A-I-T-T-T-A-K-T-D-A-E-A-K-A-L-L-A-A-F-K-F-P-F-R-N


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-N-R-I-K-K-G-D-Q-V-V-I-N-T-G-K-D-K-G-K-Q-G-E-V-V-R-V-E-G-D-R-V-I-V-S-N-A-N-V-I-K-R-H-T-K-P-N-P-Q-A-G-V-A-G-G-V-V-E-R-E-A-S-I-H-I-S-N-V-N-I-V-N-P-A-T-G-K-G-E-R-V-G-F-K-V-L-E-D-G-R-K-L-R-V-F-R-S-S-G-E-A-L-D-A


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-D-N-N-E-K-Q-T-L-R-T-V-E-G-R-V-V-S-N-K-M-D-K-T-V-T-V-L-V-E-R-Q-V-K-H-P-L-Y-G-K-Y-I-K-R-S-S-K-L-H-A-H-D-A-D-N-A-C-N-E-G-D-V-V-R-V-T-E-I-A-P-M-S-K-T-K-N-W-R-V-V-E-I-V-T-R-A-A-V


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-Y-R-K-M-H-K-G-R-N-D-G-L-A-W-S-G-N-A-V-S-F-G-E-Y-G-L-K-A-T-A-H-G-Q-L-T-A-R-Q-I-E-A-A-R-R-T-I-S-R-H-V-K-K-G-G-K-M-W-I-R-V-F-P-D-K-P-I-T-K-K-P-I-E-V-R-M-G-S-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-R-M-I-Y-E-I-E-G-I-P-E-D-I-A-R-E-A-F-R-L-A-A-A-K-L-S-V-T-T-T-F-V-T-R-T-V-R


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-V-D-H-H-L-A-K-K-V-E-S-A-A-G-S-K-K-P-I-K-T-W-S-R-R-S-M-I-L-P-E-M-V-G-I-T-I-A-V-H-N-G-K-N-H-I-P-V-L-V-N-E-N-M-V-G-H-K-L-G-E-F-A-V-T-R-T-F-K-G-H-G-G-D-K-K-S-S-R


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-S-N-E-K-I-F-S-V-L-R-A-P-R-V-S-E-K-T-A-R-L-Q-E-I-S-N-Q-Y-V-F-E-V-S-N-E-A-T-K-A-D-V-K-A-A-V-E-Q-L-F-D-V-K-V-K-A-V-N-V-V-N-V-K-G-K-S-K-S-F-R-N-R-A-G-S-R-G-N-W-R-K-A-Y-V-R-L-V-D-G-Q-S-I-D-V-T-A-K-A


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-D-Q-K-I-R-I-R-L-K-A-F-D-H-R-L-I-D-R-S-A-S-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-K-I-E-R-Y-T-I-L-V-S-P-H-A-D-K-D-A-R-D-Q-Y-E-T-R-T-H-K-R-V-L-D-I-V-D-P-N-D-K-T-V-D-A-L-M-K-L-E-L-A-A-G-V-D-V-Q-I-K-L-T


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-G-S-T-P-Q-R-T-V-L-P-D-P-K-H-G-S-E-T-I-A-R-F-I-N-M-V-M-Q-S-G-K-K-S-V-A-E-K-I-V-Y-G-A-M-D-V-I-G-E-K-N-P-N-A-V-E-L-V-Q-K-A-L-D-N-V-A-P-A-V-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-S-S-R-R-M-A-L-A-M-R-W-L-I-D-S-A-R-K-R-G-E-N-T-M-P-R-K-L-A-A-E-L-L-D-A-S-E-S-R-G-G-A-I-K-K-R-E-E-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-L-T-N-E-Q-I-V-D-A-I-A-E-K-S-L-M-E-V-M-E-L-V-K-A-I-E-E-K-F-G-V-S-A-A-A-P-V-A-A-A-A-A-G-P-A-A-V-V-E-E-Q-T-E-F-T-V-V-L-T-S-P-G-A-N-K-V-A-A-I-K-A-V-R-G-V-T-G-L-G-L-K-E-A-K-D-L-T-E-A-G-G-I-L-K-E-G-V-S-K-D-E-A-E-K-I-K-K-E-M-T-E-A-G-A-T-V-E-V-K


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-A-L-R-L-I-V-G-L-G-N-P-G-P-E-H-A-Q-T-R-H-N-A-G-F-R-F-V-D-A-L-A-E-R-T-G-A-R-W-G-L-D-S-K-L-F-G-E-T-A-K-A-E-I-A-G-H-T-V-W-L-L-K-P-A-T-F-M-N-L-S-G-K-S-I-T-A-A-L-R-F-W-K-I-E-P-E-Q-L-L-V-A-H-D-E-L-D-L-A-P-G-T-A-R-L-K-F-D-G-G-H-G-G-Q-N-G-L-R-D-T-I-R-L-L-G-H-G-K-F-H-R-L-R-V-G-I-G-H-P-G-H-K-D-R-V-V-P-W-V-L-G-R-A-G-R-D-D-D-M-A-I-G-E-A-V-D-A-A-I-D-A-L-P-L-A-L-D-G-N-F-N-E-A-M-K-R-L-H-T-P-K-K


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-S-R-L-L-L-I-V-L-L-A-C-S-I-A-S-A-I-G-V-V-Y-M-R-H-M-H-R-K-L-F-V-Q-L-S-K-L-E-H-S-R-D-E-L-N-I-E-F-G-R-L-Q-L-E-Q-A-T-W-A-E-S-N-R-V-D-Q-V-S-R-E-R-I-G-M-K-F-P-E-T-S-D-I-V-V-I-R-P


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-S-K-P-G-G-H-A-R-H-G-R-R-D-G-I-D-P-V-L-R-S-R-A-R-R-R-A-L-Q-A-V-Y-A-W-Q-I-A-G-G-F-A-K-Q-V-I-A-Q-F-A-H-E-Q-A-H-E-V-A-D-L-A-Y-F-E-S-L-V-E-G-V-L-S-N-R-S-E-L-D-T-A-L-T-P-Y-L-D-R-G-V-E-E-V-D-A-I-E-R-A-V-L-R-L-A-A-Y-E-L-L-Y-R-Q-D-V-P-Y-R-V-V-I-N-E-A-I-E-T-A-K-R-F-G-S-E-H-G-H-T-Y-V-N-G-V-L-D-R-A-A-V-E-W-R-K-M-E-S-G-A-S-G-A


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-Q-H-N-D-T-R-V-I-D-S-R-V-S-E-D-G-T-T-I-R-R-R-R-E-C-E-A-C-G-E-R-F-S-T-L-E-T-I-E-L-K-L-P-T-V-V-K-S-D-G-G-R-E-A-F-D-A-R-K-L-R-T-S-F-D-R-A-L-Q-K-R-P-V-S-E-E-Q-I-E-A-A-V-R-A-V-V-H-Q-L-R-M-S-G-E-R-E-V-G-S-L-R-V-G-E-Y-V-M-V-E-L-R-K-L-D-H-V-G-Y-V-R-F-A-S-V-Y-R-S-F-Q-D-V-A-D-F-R-E-E-I-E-K-L-E-R-E-L-P-V-G-S-E-Q-L-P-L-L-E-A-A-L-E-R-A-G-K-P-G-K-R


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-Q-A-L-T-L-A-R-P-Y-A-R-A-A-F-A-I-A-R-E-G-G-K-F-A-P-W-S-D-A-L-A-F-S-A-Q-V-A-G-D-P-R-V-A-A-L-L-L-N-P-A-L-H-Q-D-Q-A-V-T-L-L-A-P-P-A-A-E-A-D-Y-Q-R-F-L-G-L-L-A-D-A-Q-R-L-A-L-L-P-E-I-A-G-L-Y-E-Q-L-R-A-E-A-E-H-V-V-K-A-T-V-T-S-A-T-D-M-S-P-A-E-L-A-T-I-T-A-A-L-K-K-R-F-G-R-E-V-D-V-T-T-A-V-D-A-S-L-I-G-G-A-V-I-D-T-G-E-M-V-I-D-G-S-L-K-G-K-L-A-R-L-Q-N-S-L-A-H


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-I-T-L-T-I-F-A-Q-A-L-A-F-A-G-L-I-W-I-V-A-T-K-I-W-P-P-L-L-K-A-I-E-E-R-Q-Q-K-I-A-E-G-L-A-A-A-D-R-S-Q-K-D-L-A-Q-A-Q-E-K-V-N-E-A-L-K-D-A-R-T-K-A-N-E-I-I-D-Q-A-H-A-R-A-N-Q-I-I-E-A-A-K-L-E-A-I-A-E-A-N-R-Q-K-D-L-A-Q-A-E-I-D-A-S-A-T-R-A-R-E-E-L-R-R-Q-V-S-S-L-A-V-S-G-A-E-K-L-L-K-R-E-I-D-A-T-A-H-K-A-L-L-D-E-L-A-A-E-I


### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-T-L-V-S-L-P-T-A-A-P-A-P-D-Y-Q-S-I-D-R-P-L-N-F-S-N-A-A-A-A-K-V-R-E-L-I-Q-E-E-G-N-A-E-L-A-L-R-V-Y-I-Q-G-G-G-C-S-G-F-Q-Y-G-F-E-F-D-E-N-R-A-E-D-D-L-A-V-A-T-D-G-V-T-L-L-V-D-P-L-S-L-Q-Y-L-M-G-A-E-V-D-Y-T-E-S-L-T-G-A-Q-F-V-I-R-N-P-N-A-K-T-T-C-G-C-G-S-S-F-S-V


### FUNCTION Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA ### SEQUENCE -M-L-V-L-L-N-K-P-Y-G-V-L-S-Q-F-S-D-R-S-T-P-P-K-R-T-L-A-E-F-G-L-P-P-Q-V-Y-A-A-G-R-L-D-H-D-S-E-G-L-L-L-L-T-D-D-G-P-L-A-H-R-L-T-D-P-R-H-K-Q-P-K-T-Y-W-V-Q-V-E-G-D-P-D-T-S-Q-L-Q-A-L-C-D-G-V-L-L-N-D-G-P-T-R-P-A-N-V-R-R-L-E-C-A-P-T-L-W-P-R-D-P-P-V-R-V-R-K-T-V-P-D-A-W-L-E-V-Q-I-T-E-G-R-N-R-Q-V-R-R-M-T-A-S-V-G-L-P-T-L-R-L-V-R-V-A-I-G-A-W-S-L-A-S-L-Q-P-G-Q-W-R-V-D-D-A-R-A-V-R-P-A-R


### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-D-E-I-L-N-G-A-A-A-P-A-D-A-A-A-G-P-A-F-T-I-E-K-I-Y-V-K-D-V-S-F-E-S-P-N-A-P-A-V-F-N-D-A-N-Q-P-E-L-Q-L-N-L-N-Q-K-V-Q-R-L-N-D-N-A-F-E-V-V-L-A-V-T-L-T-C-T-A-G-G-K-T-A-Y-V-A-E-V-Q-Q-A-G-V-F-G-L-V-G-L-E-P-Q-A-I-D-V-L-L-G-T-Q-C-P-N-I-L-F-P-Y-V-R-T-L-V-S-D-L-I-Q-A-G-G-F-P-P-F-Y-L-Q-P-I-N-F-E-A-L-Y-A-E-T-L-R-Q-R-S-Q-G-E-T-S-L-A-D-S-E-P-A-G-N-A


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-A-S-N-P-C-R-R-F-P-R-S-A-R-V-R-T-R-A-Q-Y-T-I-V-F-D-T-A-R-R-T-S-D-P-L-L-S-L-H-W-R-T-G-D-T-P-P-R-L-G-M-A-V-S-R-K-V-D-T-R-A-V-G-R-N-R-I-K-R-V-L-R-D-A-M-R-H-L-L-P-E-L-A-G-G-D-Y-V-I-V-A-R-S-A-A-A-K-A-T-N-P-Q-I-R-D-A-F-L-R-L-L-H-R-A-G-A-L-P-L-P-A-A-A-G-T-M-P-P-A-R-T-V-H-P-S-S-L-S-P-T-E-P-E-L


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-F-S-I-W-H-W-L-I-V-L-V-I-V-L-L-V-F-G-T-K-R-L-T-S-G-A-K-D-L-G-S-A-V-K-E-F-K-K-G-M-H-D-D-D-K-P-A-G-K-L-G-D-D-S-R-T-A-E-Q-A-R-E-A-Q-A-E-R-D-R-D-A-R


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-S-P-F-S-I-V-L-I-G-F-A-M-S-T-D-A-F-A-A-A-I-G-K-G-A-A-M-R-K-P-Q-W-R-D-A-L-R-A-G-L-I-F-G-C-I-E-A-I-T-P-V-I-G-W-L-L-G-R-A-A-A-S-Y-V-S-A-Y-D-H-W-I-A-F-V-L-L-G-A-L-G-T-H-M-I-V-A-G-L-R-N-G-P-E-D-A-E-D-A-A-S-D-T-P-K-R-H-G-V-L-G-L-A-T-T-G-F-A-T-S-I-D-A-M-A-V-G-V-S-L-A-F-L-D-V-H-I-G-V-V-A-V-V-V-G-L-C-T-F-S-M-V-T-A-G-V-M-L-G-R-A-L-G-N-L-I-G-K-R-A-E-M-L-G-G-L-I-L-V-I-V-G-S-V-I-L-Y-E-H-L-S-G-A-G


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-S-P-P-T-Q-S-L-Q-V-K-L-L-D-P-R-F-G-D-L-W-P-L-P-A-Y-A-T-E-S-S-A-G-M-D-L-R-A-A-L-E-A-P-M-T-L-Q-P-G-D-A-A-L-I-P-S-G-I-A-I-H-L-A-D-P-Q-L-C-A-V-I-L-P-R-S-G-L-G-H-R-H-G-I-V-L-G-N-G-T-G-L-I-D-A-D-Y-Q-G-P-L-L-I-S-T-W-N-R-G-R-E-A-F-T-I-E-P-G-D-R-I-A-Q-L-V-I-L-P-I-V-R-M-G-L-Q-V-V-D-T-F-V-D-S-A-R-G-A-G-G-F-G-H-T-G-V-R


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-L-L-P-I-L-E-F-P-D-P-R-L-R-T-K-A-V-P-V-D-A-A-E-V-T-S-Q-A-F-Q-T-L-L-D-D-M-F-H-T-M-Y-E-A-P-G-I-G-L-A-A-S-Q-V-D-V-H-K-R-F-M-V-I-D-I-S-D-E-K-N-L-P-Q-V-F-V-N-P-E-I-V-S-K-Q-G-E-Q-L-Y-Q-E-G-C-L-S-V-P-G-I-Y-A-D-V-S-R-A-D-A-I-T-V-R-Y-L-D-R-Q-G-Q-P-Q-E-L-H-A-D-G-L-L-A-V-C-I-Q-H-E-M-D-H-L-D-G-K-L-F-V-D-Y-L-S-P-L-K-R-E-M-V-R-K-K-L-A-K-Q-R-K-H-V-A


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-I-T-L-T-I-F-A-Q-A-L-A-F-A-G-L-I-W-I-V-A-T-K-I-W-P-P-L-L-Q-A-I-E-E-R-Q-Q-K-I-A-E-G-L-A-A-A-D-R-S-Q-K-D-L-A-Q-A-Q-E-K-V-N-E-A-L-K-D-A-R-T-K-A-N-E-I-I-D-Q-A-H-A-R-A-N-Q-I-I-E-A-A-K-L-E-A-I-A-E-A-N-R-Q-K-D-L-A-Q-T-E-I-D-A-S-A-T-R-A-R-E-E-L-R-K-Q-V-S-V-L-A-V-S-G-A-E-K-L-L-K-R-E-I-D-A-N-A-H-K-A-L-L-D-E-L-A-A-E-I


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-Q-A-L-T-L-A-R-P-Y-G-R-A-A-F-A-I-A-R-E-G-G-N-F-A-P-W-S-D-A-L-A-F-S-A-Q-V-A-G-D-P-R-V-A-A-L-L-L-N-P-A-L-G-Q-E-Q-A-V-T-L-L-A-P-P-Q-A-G-E-D-Y-L-R-F-L-G-V-L-A-D-A-Q-R-L-S-L-L-P-E-V-A-G-L-Y-E-H-L-R-A-E-A-E-H-V-V-K-A-T-V-T-S-A-A-A-M-S-Q-T-E-L-D-T-I-A-A-A-L-K-K-R-F-G-R-D-V-D-I-T-T-A-V-D-A-S-L-I-G-G-A-V-I-D-T-G-D-V-V-I-D-G-S-L-K-G-K-L-A-R-L-Q-S-S-L-A-H


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-T-I-R-C-D-I-V-S-A-E-K-E-I-F-H-G-E-A-T-L-V-V-A-T-G-E-L-G-E-L-G-I-A-P-K-H-A-P-L-I-T-R-L-K-P-G-K-V-V-V-T-T-A-N-G-E-Q-L-D-F-A-I-S-G-G-I-L-E-V-Q-P-Q-V-V-T-I-L-V-D-T-A-V-R-A-Q-D-I-D-E-A-A-V-R-K-V-K-E-E-A-E-R-L-L-A-N-R-G-N-T-V-D-V-A-E-A-Q-R-Q-L-A-E-A-T-V-Q-L-Q-A-L-E-R-L-R-R-N-L-K-H


### FUNCTION Catalyzes the hydrolysis of inorganic pyrophosphate  forming two phosphate ions ### SEQUENCE -M-G-L-E-L-V-T-S-G-K-N-L-P-E-E-I-N-V-V-I-E-I-P-K-D-S-E-P-V-K-Y-E-V-D-K-A-S-G-A-I-F-V-D-R-I-L-S-T-P-M-R-Y-P-C-N-Y-G-Y-V-P-N-T-L-C-G-D-G-D-P-A-D-V-L-V-V-L-P-L-P-L-V-P-G-S-V-V-R-C-R-P-V-G-V-L-R-M-S-D-E-A-G-S-D-E-K-I-L-A-V-P-I-E-K-I-F-S-G-Y-A-H-I-E-D-I-N-Q-V-S-S-H-W-M-E-R-I-G-H-F-F-E-H-Y-K-D-L-E-K-G-K-W-V-K-L-D-G-W-G-G-A-A-E-A-K-R-I-L-T-E-S-V-E-R-Y-N-S-D-A-P


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-G-M-V-S-E-F-K-Q-F-A-M-R-G-N-V-I-D-L-A-V-G-V-V-I-G-A-A-F-G-K-I-V-T-A-L-V-E-K-I-I-M-P-P-I-G-W-A-I-G-N-V-D-F-S-R-L-A-W-V-L-K-P-A-G-V-D-A-T-G-K-E-I-P-A-V-A-I-G-Y-G-D-F-I-N-T-V-V-Q-F-L-I-I-A-F-A-I-F-L-V-V-K-L-I-N-R-V-T-H-R-K-P-D-A-P-K-G-P-S-E-E-V-L-L-L-R-E-I-R-D-A-L-K-N-D-T-L-K-P-P-G-A-L


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-L-R-G-I-L-A-Y-K-Q-P-P-W-L-V-I-D-V-G-G-V-G-Y-E-L-E-A-P-M-S-T-F-Y-D-L-P-D-V-G-R-D-V-I-L-F-T-H-Y-A-Q-K-E-D-S-V-S-L-Y-G-F-L-R-E-G-E-R-R-L-F-R-D-V-Q-K-V-T-G-I-G-A-K-I-A-L-A-V-L-S-G-V-S-V-D-E-F-A-R-L-I-T-S-G-D-I-T-A-L-T-R-I-P-G-I-G-K-K-T-A-E-R-M-V-V-E-L-R-D-R-A-A-D-F-S-S-G-A-P-I-T-G-Q-L-G-P-D-A-V-S-E-A-T-V-A-L-Q-Q-L-G-Y-K-P-A-E-A-A-R-M-A-R-D-A-G-A-E-G-D-E-V-A-T-V-I-R-K-A-L-Q-A-A-L-R


### FUNCTION Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone  biosynthetic pathway ### SEQUENCE -M-S-G-I-T-R-D-S-R-P-A-L-R-A-G-V-R-L-Q-Q-D-R-A-R-D-Q-W-V-L-L-A-P-E-R-V-V-E-L-D-D-I-A-L-V-V-A-Q-R-Y-D-G-T-R-S-L-A-Q-I-A-Q-E-L-A-A-E-F-D-A-D-A-A-Q-I-E-A-D-V-I-E-L-T-D-T-L-H-Q-K-R-L-L-R-L


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-E-I-P-G-D-L-K-F-L-K-S-H-E-W-A-R-V-E-S-N-G-R-V-T-V-G-I-S-D-H-A-Q-G-L-L-G-D-L-V-Y-V-E-L-P-G-V-G-D-T-V-Q-V-G-N-G-A-A-V-V-E-S-V-K-A-A-S-D-V-Y-S-P-V-S-G-T-V-V-E-V-N-S-A-L-S-D-K-P-E-T-I-N-E-D-A-Y-G-E-G-W-I-F-V-V-E-I-D-D-K-E-Q-L-N-D-L-L-D-P-D-D-Y-A-E-L-L-E-D-D-D-H


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-P-E-A-G-A-I-R-P-D-G-T-V-L-G-F-D-V-G-S-R-R-I-G-V-A-V-G-S-A-L-G-A-G-A-R-A-V-A-V-I-N-V-H-A-N-G-P-D-W-V-A-L-D-R-V-H-K-Q-W-R-P-D-G-L-V-V-G-D-P-L-T-L-D-D-K-D-Q-P-A-R-K-R-A-H-A-F-A-R-Q-L-R-E-R-Y-A-L-P-V-V-L-I-D-E-R-S-S-S-V-E-A-A-Q-R-F-A-R-E-R-A-D-G-R-K-R-R-R-D-A-E-A-L-D-A-M-A-A-A-V-I-V-E-R-W-L-A-A-P-D-Q-A-T-L-L-P


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-R-G-I-N-K-V-I-L-V-G-N-L-G-N-D-P-D-T-K-Y-T-Q-A-G-M-A-I-T-R-V-S-L-A-T-T-S-M-R-K-D-R-D-G-N-N-Q-E-R-T-E-W-H-R-V-V-F-F-G-K-L-G-E-I-A-G-E-Y-L-R-K-G-S-Q-V-Y-V-E-G-E-L-R-Y-D-K-Y-T-G-Q-D-G-V-E-K-Y-S-T-D-I-V-A-N-E-M-Q-M-L-G-G-R-G-E-G-G-G-G-G-M-G-G-D-R-P-Q-R-S-A-P-R-Q-Q-G-G-G-G-G-Q-G-G-G-G-Y-G-G-G-G-G-G-G-G-Q-D-Y-A-P-R-R-Q-Q-P-A-Q-Q-Q-S-A-P-P-M-D-D-F-A-D-D-D-I-P-F


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-K-C-R-L-I-A-T-G-E-R-A-P-S-W-V-A-Q-G-F-A-E-Y-Q-K-R-L-S-H-W-M-P-L-E-L-V-E-I-E-P-G-M-R-G-K-G-R-D-A-Q-R-A-T-D-D-E-G-R-R-V-L-A-A-L-P-K-N-A-Y-V-V-A-L-D-V-P-G-R-P-L-S-S-E-Q-L-A-Q-R-M-E-H-W-R-G-Q-G-R-D-L-A-F-L-I-G-G-P-E-G-H-A-A-E-V-L-K-S-A-S-E-S-W-S-I-G-P-L-T-L-P-H-M-L-V-R-L-I-V-A-E-Q-L-Y-R-A-A-A-M-L-A-N-H-P-Y-H-R-A


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-K-K-S-L-N-E-T-S-P-V-A-R-F-E-Q-S-L-E-E-L-E-Q-L-V-Q-K-M-E-V-G-D-L-S-L-E-Q-S-L-T-A-Y-E-R-G-I-G-L-Y-R-D-C-Q-Q-A-L-E-Q-A-E-L-R-V-R-L-L-T-D-P-A-R-P-E-L-A-E-A-F-E-P-P-S-L-D-G


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-S-R-W-R-P-P-A-E-K-S-T-A-L-I-T-P-E-G-H-A-R-L-K-A-E-L-D-D-L-W-R-V-R-R-P-E-V-V-R-A-L-A-A-A-A-A-E-G-D-R-S-E-N-A-E-Y-T-Y-R-K-K-Q-L-G-E-I-D-R-R-V-R-Y-L-S-K-R-L-E-A-L-R-V-V-D-T-A-P-T-D-A-N-A-V-F-F-G-A-Q-V-E-L-E-D-A-G-S-G-E-L-L-R-Y-R-I-V-G-P-D-E-T-D-A-G-R-G-W-I-S-I-D-S-P-L-A-R-A-L-L-K-K-R-V-D-D-E-F-D-A-H-L-P-A-G-K-H-T-F-V-V-V-S-V-D-Y-A-S-L


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-E-K-A-T-E-I-A-N-L-L-S-P-T-V-E-S-L-G-L-E-L-L-G-V-E-Y-L-P-A-P-G-G-A-T-L-R-L-Y-I-D-V-P-L-A-E-Q-P-E-R-V-I-N-V-D-D-C-E-R-V-S-R-E-V-S-A-Q-L-D-V-E-D-P-I-S-G-N-Y-T-L-E-V-S-S-P-G-V-D-R-P-L-F-T-L-E-Q-F-A-R-H-T-G-E-S-A-K-I-V-L-K-L-A-Q-D-G-R-R-R-F-Q-G-Q-I-L-R-I-D-A-E-A-A-A-V-V-F-A-V-D-G-K-D-V-Q-I-G-Y-D-N-I-D-K-A-R-I-V-P-D-W-V-A-L-G-L-A-P-Q-K-P-N-K-P-G-P-K-K-P-G-H-E-K-K-K-P-S-N-E-S-A-A-G-K-P-R-A-E


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-T-K-S-F-H-R-T-D-R-V-S-A-Q-V-R-R-D-L-G-T-I-V-H-A-A-V-R-D-N-G-L-P-S-V-S-V-S-D-V-E-I-S-R-D-L-A-H-A-K-V-F-V-T-A-L-Q-Q-E-R-S-A-E-A-V-K-G-L-K-E-I-A-G-Q-L-R-T-Q-L-A-R-A-M-K-L-R-H-V-P-E-L-H-F-H-Y-D-D-S-V-D-R-G-E-R-I-D-N-L-L-R-D-L-D-D-V-G-P-E-A-T-S-S-D-E-D-A-E-Q-R


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-V-D-T-Q-K-V-I-E-D-N-K-R-S-A-Q-D-T-G-S-P-E-V-Q-V-A-L-L-T-A-R-I-E-L-L-T-G-H-F-K-T-H-K-K-D-H-H-S-R-R-G-L-L-Q-M-V-N-R-R-R-S-L-L-D-Y-L-K-K-K-D-N-E-R-Y-K-S-L-I-E-K-L-G-L-R-R


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-P-L-G-D-C-N-I-S-T-P-D-N-K-Q-N-R-K-N-Q-E-I-R-V-P-R-V-R-V-I-G-S-D-G-E-M-V-G-V-L-S-R-D-E-A-L-A-K-A-E-E-E-G-L-D-L-V-E-I-Q-P-Q-A-D-P-P-V-C-K-I-M-D-F-G-K-F-K-F-E-Q-Q-K-K-A-N-E-A-K-K-K-T-K-Q-V-E-I-K-E-L-K-F-R-P-V-T-D-E-G-D-Y-Q-I-K-L-R-N-M-R-R-F-L-E-E-G-D-K-V-K-V-N-I-R-F-R-G-R-E-M-S-H-Q-E-L-G-R-E-M-A-A-R-I-E-A-D-L-G-D-D-I-V-I-E-S-R-P-R-L-E-G-R-Q-M-V-M-M-I-A-P-K-K-K-V


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-Q-A-R-R-R-H-K-K-I-L-T-L-A-K-G-Y-Y-N-A-R-R-K-V-F-R-V-A-K-Q-A-V-I-K-A-Q-Q-Y-A-Y-I-G-R-K-Q-K-K-R-N-F-R-S-L-W-I-T-R-I-N-A-A-A-R-I-N-G-L-S-Y-S-R-F-M-N-G-L-L-K-A-G-I-T-L-D-R-K-V-L-A-D-I-A-V-H-D-A-A-G-F-A-A-L-A-E-K-A-K-G-A-L-A-A


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-K-G-P-V-R-L-D-V-A-V-S-Y-A-L-P-R-A-G-L-P-S-A-V-S-F-R-K-W-V-A-A-A-L-K-G-R-I-R-E-A-D-L-A-V-R-V-V-D-E-K-E-G-C-S-L-N-H-H-Y-R-G-K-D-Y-A-T-N-V-L-S-F-P-A-E-L-P-E-G-L-P-K-G-I-K-M-P-L-L-G-D-L-V-I-C-A-P-V-V-A-R-E-A-A-E-Q-G-K-S-L-A-A-H-Y-A-H-L-T-V-H-G-T-L-H-L-L-G-W-D-H-E-D-D-K-E-A-E-A-M-E-Q-L-E-R-E-I-L-A-D-L-G-I-D-D-P-Y-A-G-E-H


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-D-C-S-R-C-A-G-T-N-T-S-G-P-N-H-W-P-E-R-I-R-D-I-V-D-F-P-K-P-G-I-V-F-K-D-I-T-P-L-L-S-D-G-P-D-F-A-S-A-L-D-E-M-A-Q-P-W-R-T-T-P-L-D-A-V-L-G-I-E-A-R-G-F-I-L-G-A-A-L-A-R-E-L-R-T-G-F-V-P-V-R-K-P-G-K-L-P-G-R-T-L-I-Q-E-Y-A-L-E-Y-G-T-D-R-I-E-M-H-E-D-A-L-P-R-G-A-R-V-L-I-V-D-D-V-L-A-T-G-G-T-L-R-A-A-L-G-L-A-A-Q-L-E-L-E-V-V-G-A-A-V-L-V-E-L-Q-G-L-Q-G-R-Q-K-W-A-N-D-V-P-L-L-A-T-L-S-Y


### FUNCTION Involved in peptide bond synthesis Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome Modification of Lys-34 is required for alleviation ### SEQUENCE -M-A-T-V-G-M-N-D-V-K-N-G-M-K-I-L-V-N-N-E-P-A-V-I-T-E-T-E-Y-V-K-P-G-K-G-Q-A-F-T-R-M-K-Y-R-F-I-K-S-G-R-V-V-E-M-T-M-K-A-T-D-D-V-E-V-A-D-V-V-D-T-D-M-R-Y-L-Y-S-D-G-E-Y-W-H-F-M-D-P-D-T-F-E-Q-V-Q-T-D-K-A-G-M-G-G-A-D-K-W-L-K-G-E-E-D-C-I-V-T-L-W-N-G-T-P-I-W-V-Q-P-P-N-F-V-E-L-K-I-T-E-T-D-P-G-V-R-G-D-T-S-G-G-G-G-K-P-A-T-L-E-T-G-A-V-V-R-V-P-L-F-V-N-Q-D-E-I-I-K-V-D-T-R-S-G-E-Y-S-A-R-V-K


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-I-L-A-R-R-Q-A-H-L-K-S-D-D-V-D-L-A-V-K-S-L-L-E-M-M-G-Q-A-L-S-D-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-P-P-R-L-G-R-N-P-K-T-G-E-S-V-A-L-P-G-K-H-V-P-H-F-K-P-G-K-E-L-R-E-R-V-S-S-V-V-P-V-D-V-A-D-T-A-D


### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-Q-I-S-D-K-A-Q-T-Y-F-R-K-L-I-E-R-E-G-V-P-G-M-G-V-R-L-S-A-V-D-A-G-T-P-R-A-D-A-R-L-E-F-A-E-P-A-D-L-S-G-D-E-W-A-I-D-C-D-G-F-T-L-Y-V-V-A-A-S-V-P-W-M-D-G-A-E-I-D-Y-V-T-Q-S-T-G-N-Q-Q-L-T-I-K-A-P-K-I-K-G-E-A-P-A-E-S-A-S-M-V-E-R-V-R-W-V-V-E-N-E-I-N-P-Q-L-A-S-H-G-G-R-V-A-V-Q-E-V-S-A-E-G-V-V-L-L-R-F-G-G-G-C-H-G-C-G-M-A-D-V-T-L-K-Q-G-I-E-K-T-L-M-G-R-V-P-G-V-T-A-V-R-D-A-T-D-H-A-T-G-D-A-P-Y-I-P-R-D-S-A-A


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-E-N-L-A-G-N-D-R-L-I-W-I-D-L-E-M-T-G-L-D-T-D-R-D-S-I-I-E-I-A-T-I-V-T-D-A-Q-L-N-V-L-A-E-G-P-E-L-A-I-A-H-P-L-E-T-L-E-A-M-D-E-W-N-R-N-Q-H-R-R-S-G-L-W-Q-R-V-I-D-S-Q-V-T-H-A-Q-A-E-A-Q-T-V-A-F-L-S-E-W-I-R-A-G-A-S-P-M-C-G-N-S-I-C-Q-D-R-R-F-L-H-R-Q-M-S-R-L-E-R-Y-F-H-Y-R-N-L-D-V-S-T-I-K-E-L-A-R-R-W-A-P-T-V-A-N-G-F-A-K-S-S-A-H-T-A-L-S-D-V-R-D-S-I-D-E-L-R-H-Y-R-Q-F-M-G-A-L-G-G-D-T-A-A-G-V-E-N


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-A-P-V-W-W-Q-Q-L-L-L-A-M-T-G-G-A-L-G-S-G-L-R-F-A-I-G-A-S-L-I-Q-R-F-G-N-V-F-P-W-G-T-L-T-V-N-L-L-G-S-F-V-A-G-V-L-L-V-W-L-D-A-R-G-P-S-S-W-P-L-R-A-L-L-I-V-G-V-I-G-G-L-T-T-F-S-S-L-M-M-E-C-L-V-F-A-R-T-D-R-S-T-M-I-G-I-Y-L-A-V-T-L-L-A-G-L-A-L-V-F-A-G-A-R-T-G-Q-W-L-V-T-R


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-S-I-E-F-E-G-S-V-S-E-T-L-P-N-T-T-F-R-V-K-L-E-N-G-H-E-I-I-A-H-I-S-G-R-M-R-K-N-Y-I-R-I-L-T-G-D-R-V-K-V-E-M-T-P-Y-D-L-T-K-G-R-I-T-Y-R-M-K


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-P-R-N-T-S-H-E-H-D-H-G-L-M-V-E-A-S-K-P-E-V-A-P-P-P-R-Y-Q-V-L-L-L-N-D-D-Y-T-P-M-D-F-V-V-T-V-L-E-Q-F-F-N-L-N-L-E-Q-A-T-Q-I-M-L-H-V-H-T-R-G-R-G-V-C-G-V-Y-S-R-E-V-A-E-S-K-V-A-Q-V-N-E-F-S-R-M-N-Q-H-P-L-L-C-T-M-E-Q-A


### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-S-T-A-V-Q-V-D-D-V-M-R-Y-R-D-S-R-F-Q-T-I-A-A-K-L-L-P-T-Q-Y-L-V-V-D-D-D-T-A-L-T-T-T-L-G-S-C-V-A-A-C-L-R-D-P-V-L-K-I-G-G-M-N-H-F-L-L-P-E-G-Q-V-G-D-G-A-P-T-R-Y-G-S-Y-A-M-E-L-L-I-N-D-M-L-K-R-G-A-H-R-K-R-I-E-A-K-V-F-G-G-A-N-V-L-K-G-F-T-S-N-P-V-G-T-R-N-A-E-F-V-R-Q-Y-L-Q-A-E-H-I-P-I-I-A-E-D-L-C-G-I-H-P-R-K-V-W-F-F-A-T-T-G-R-V-V-V-Q-R-L-P-H-A-H-E-A-E-V-A-A-T-E-S-A-V-R-A-R-L-S-K-A-P-V-T-G-G-V-E-L-F-E


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-R-A-P-M-T-S-K-G-A-Q-R-L-R-E-E-L-E-H-L-K-S-V-K-R-P-E-V-I-N-A-I-A-E-A-R-A-H-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-Q-Q-S-F-I-E-G-R-I-K-Q-L-E-S-E-L-S-H-A-E-I-I-D-I-T-K-L-S-A-G-T-K-I-V-F-G-A-T-V-T-L-A-D-T-E-T-D-E-E-K-R-Y-Q-I-V-G-D-L-E-A-D-I-K-M-G-L-I-A-I-S-S-P-L-A-R-A-L-I-G-K-L-E-G-D-S-V-T-I-D-A-P-A-G-Q-R-E-Y-E-V-V-S-V-A-Y-L-D


### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-M-I-G-D-S-V-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-I-T-A-P-K-D-V-A-V-H-R-E-E-I-Y-Q-R-I-Q-R-G-D-E-P-V-A-S-G-A-H-H-G-D-D-S-S-N


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-V-P-V-S-V-Y-L-V-N-G-I-K-L-Q-G-T-I-E-S-F-D-Q-F-V-V-L-L-R-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-N-V-R-V-G-P-G-G-G-Y-V-Q-S-N-E-G-N-Q-A-E-D-D-D-V-E-Q


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-N-W-R-W-L-L-L-V-L-A-V-L-L-A-W-L-Q-Y-R-F-W-F-G-P-G-N-S-G-E-V-M-M-L-E-A-Q-V-A-H-Q-T-Q-D-N-E-G-L-R-Q-R-N-Q-A-L-A-A-E-V-K-D-L-K-D-G-E-A-A-I-E-E-R-A-R-S-E-L-G-M-I-K-P-G-E-T-F-Y-R-V-V-E-D-A-P-L-P-A-P-A-S-A-E-A-S-A-P-A-Q-Q-A-P-E-P-V-D-P-V-D-H-P


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-D-L-I-L-L-Q-K-V-T-N-L-G-N-L-G-D-K-V-S-V-K-P-G-Y-G-R-N-F-L-V-P-Q-G-K-A-V-P-A-T-A-A-N-V-E-A-F-E-T-K-R-A-E-Y-E-A-K-A-N-S-I-L-A-E-A-Q-S-R-A-T-K-F-E-G-A-S-V-T-I-G-A-H-A-S-T-E-G-K-L-Y-G-S-V-G-P-R-D-I-A-E-A-F-T-A-A-G-L-P-L-E-K-S-E-V-I-L-G-E-G-A-F-R-N-V-G-E-Y-D-V-V-L-H-L-H-A-D-V-E-T-T-V-K-V-I-V-E-S-D-A


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-K-F-F-R-R-R-K-F-C-K-F-T-A-E-G-V-K-E-I-D-Y-K-D-L-N-T-L-R-Q-Y-L-T-E-N-G-K-I-V-P-S-R-V-T-G-T-K-S-K-Y-Q-R-Q-L-A-T-A-V-K-R-A-R-F-L-A-L-I-P-Y-T-D-N-H-D-V


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-R-H-Y-E-V-V-F-L-V-H-P-D-Q-S-E-Q-V-P-A-M-I-E-R-Y-K-S-L-I-E-G-G-N-G-T-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-Q-N-L-V-K-A-H-Y-V-L-L-N-I-E-V-D-Q-A-V-L-S-E-L-V-E-S-F-R-F-N-D-A-V-L-R-H-L-V-V-K-R-D-G-A-D-T-E-Q-S-L-I-M-K-S-K-D-E-K-G-D-K-P-E-R-S-E-R-R-R-R-D-D-E-E-G-E-A-P-A-A-N-D-N-D-G-D-N-A-E-A-A


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-Q-D-H-P-E-F-D-S-E-D-L-S-Q-N-P-P-E-T-D-P-L-K-A-E-I-E-S-L-R-S-E-I-A-L-V-K-A-D-A-L-R-E-R-A-D-L-E-N-Q-R-K-R-I-A-R-D-V-E-N-A-R-K-F-A-N-E-K-L-L-G-E-L-L-P-V-F-D-S-L-D-A-G-L-T-A-A-G-T-E-P-S-P-L-R-D-G-L-D-M-T-Y-K-Q-L-L-K-V-A-A-D-N-G-L-T-L-L-D-P-V-G-Q-P-F-N-P-D-Q-H-Q-A-I-S-Q-G-E-A-E-G-V-A-P-G-H-V-V-Q-V-F-Q-K-G-Y-L-L-N-D-R-L-L-R-P-A-L-V-V-V-A-K-H-D


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-K-K-Q-T-K-D-K-A-N-G-A-K-A-T-K-T-I-A-L-N-K-R-A-R-H-E-Y-H-L-E-E-R-Y-E-A-G-L-A-L-Q-G-W-E-V-K-A-I-R-A-G-R-A-N-I-V-D-G-Y-A-Y-V-R-S-G-E-I-Y-L-I-G-A-Q-I-T-P-L-I-Q-A-S-T-H-T-V-P-V-E-R-R-D-R-K-L-L-L-H-R-A-E-I-D-K-V-L-S-R-V-E-R-E-G-Y-T-L-V-P-T-A-L-Y-W-S-S-N-K-V-K-L-E-I-A-L-A-K-G-K-Q-N-H-D-K-R-D-A-A-K-D-R-D-W-Q-R-D-K-Q-R-V-M-R-R-H-N-R-D-A


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-T-Q-I-K-Q-D-A-Q-T-R-M-T-K-S-I-D-A-L-R-H-S-L-T-T-I-R-T-G-R-A-S-P-A-L-L-D-G-I-K-V-K-A-Y-G-A-D-T-P-L-N-Q-V-A-S-I-S-V-S-E-G-R-S-L-V-I-S-L-F-D-K-G-M-I-K-D-V-E-K-A-I-Y-A-S-D-L-G-L-T-P-T-V-V-G-T-V-I-R-L-N-L-P-P-L-T-E-E-R-R-K-E-L-S-K-S-V-H-G-E-G-E-D-S-K-V-A-I-R-N-I-R-R-D-A-N-Q-Q-V-K-D-L-L-K-D-K-A-V-T-E-D-E-A-R-S-A-E-D-D-I-Q-K-L-T-D-K-A-I-K-D-V-D-E-V-V-K-G-K-E-Q-E-L-M-T-V


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-K-L-N-K-T-I-L-A-D-F-E-A-A-Q-I-Q-R-K-L-P-E-F-N-Q-G-D-T-V-V-V-N-V-K-V-K-E-G-N-R-E-R-V-Q-A-Y-E-G-V-V-I-G-T-K-N-A-G-L-N-S-S-F-T-V-R-K-I-S-H-G-F-G-V-E-R-V-F-Q-T-H-S-A-I-I-D-S-V-E-V-K-R-R-G-K-V-R-A-G-K-L-Y-Y-L-R-G-L-E-G-K-A-A-R-I-K-E-D-L-A-A-A-A-Q-A-K-A-A-R-Q-A-A-A-K-A-E


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-Q-N-E-R-R-I-L-L-G-R-I-V-G-A-F-G-V-K-G-E-L-K-L-E-S-W-T-E-P-R-T-A-I-F-R-Y-Q-P-W-I-V-R-S-P-S-G-Q-E-S-V-V-S-G-V-R-G-R-D-Q-G-K-N-L-I-A-V-F-P-G-V-T-D-R-D-T-V-E-A-M-H-G-T-E-I-Y-V-A-R-S-A-L-P-P-P-K-P-D-E-Y-Y-W-V-D-L-E-E-L-Q-V-E-T-V-E-G-V-K-L-G-T-V-S-H-L-F-S-T-G-S-N-D-V-V-V-V-R-G-D-R-E-R-M-I-P-F-V-F-P-D-F-V-K-S-V-D-F-E-A-N-L-I-V-V-D-W-D-P-D-F


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-R-A-K-Q-T-I-V-R-N-E-R-N-T-G-Q-R-S-M-L-R-T-A-V-K-K-V-I-K-A-L-D-A-N-D-A-A-G-A-E-A-A-F-A-V-A-Q-P-I-L-D-R-F-S-A-R-G-L-I-H-K-N-K-A-A-R-H-K-S-R-L-T-A-R-I-K-A-I-K-A-A


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-L-V-T-G-G-K-Q-Y-R-V-A-Q-G-E-T-L-R-V-E-K-L-E-V-E-A-G-N-E-I-K-F-D-T-I-L-M-L-G-D-S-D-G-I-K-L-G-D-A-L-K-G-A-S-V-T-A-K-V-V-A-H-G-R-A-D-K-V-R-I-I-K-F-R-R-R-K-H-H-M-K-R-Q-G-H-R-Q-H-Y-T-E-I-E-I-T-G-I-A-G-G-D-K-K


### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-G-L-L-D-F-L-K-S-K-K-N-T-A-E-T-A-K-N-R-L-Q-I-I-I-A-Q-E-R-N-H-R-G-G-P-D-Y-L-P-L-M-Q-R-E-L-L-E-V-I-K-K-Y-V-N-I-D-A-D-A-V-R-V-D-L-V-K-D-G-E-H-D-V-L-D-I-S-V-A-L-P-E-D-G-D-K


### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-P-R-L-I-L-A-S-T-S-V-Y-R-R-A-L-L-G-R-L-Q-L-D-F-D-T-V-R-P-E-V-D-E-Q-A-R-P-G-E-S-P-S-A-L-A-S-R-L-A-V-E-K-A-A-T-V-A-A-R-F-P-D-A-W-V-I-G-S-D-Q-V-A-D-L-D-G-Q-A-L-G-K-P-G-T-H-E-R-A-R-M-Q-L-T-A-M-S-G-Q-T-V-R-F-H-T-A-V-S-L-V-G-P-E-R-Q-L-H-A-L-D-L-T-E-V-Q-L-R-A-L-T-V-V-E-I-E-R-Y-L-D-A-E-P-A-L-D-C-A-G-S-F-K-C-E-G-L-G-I-S-L-F-D-A-I-R-S-E-D-P-T-A-L-V-G-L-P-M-I-A-L-A-R-L-L-R-Q-A-G-F-Q-I-P


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-T-L-L-E-Q-L-I-E-A-F-R-V-L-P-G-V-G-Q-K-S-A-Q-R-M-A-Y-H-V-L-E-R-E-R-E-G-G-R-R-L-A-A-A-L-G-S-A-V-E-K-V-G-H-C-V-Q-C-R-D-F-T-E-S-E-I-C-T-I-C-A-S-S-S-R-D-R-Q-Q-L-C-V-V-E-S-P-A-D-R-L-A-I-E-H-A-T-G-Y-R-G-L-Y-F-I-L-Q-G-R-L-S-P-L-D-G-I-G-P-R-E-L-G-L-D-R-L-S-E-R-L-A-A-G-E-V-T-E-M-I-I-A-T-N-A-T-V-E-G-E-A-T-A-H-Y-L-A-Q-L-A-R-Q-H-A-V-R-P-S-R-L-A-Q-G-M-P-L-G-G-E-L-E-Y-V-D-R-G-T-L-S-H-A-F-G-T-R-S-E-V-L


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-R-G-N-I-A-Q-L-M-Q-Q-A-Q-K-M-Q-E-N-L-Q-R-A-Q-E-E-L-A-K-L-E-V-T-G-T-A-G-G-G-M-V-S-V-T-L-T-G-A-K-E-C-R-K-V-R-I-D-P-S-I-L-S-D-Q-E-M-A-E-D-L-I-A-A-A-F-N-D-A-S-N-K-I-D-A-E-S-K-D-R-M-G-S-A-T-A-G-M-Q-L-P-P-G-M-K-L-P-F


### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-N-P-F-R-W-S-F-R-A-Q-F-L-L-G-F-L-A-C-A-G-L-L-A-Y-A-I-Y-V-Q-L-H-L-G-L-E-P-C-P-L-C-I-F-Q-R-I-A-F-A-A-L-A-V-F-F-L-L-G-A-L-H-G-P-R-A-A-A-G-R-K-V-Y-G-V-L-S-F-I-A-A-G-V-G-M-G-I-A-A-R-H-V-W-V-Q-I-R-P-K-D-M-M-S-S-C-G-P-P-L-S-F-L-S-E-T-M-G-P-F-E-V-F-R-T-V-L-T-G-T-G-D-C-G-N-I-D-W-R-F-L-G-L-S-M-P-M-W-S-M-V-W-F-V-G-L-A-L-W-A-L-Y-A-G-F-K-V-R-R-S-S-V-H-H


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-L-R-L-N-D-L-K-P-A-D-G-A-R-T-E-R-T-R-V-G-R-G-I-G-S-G-L-G-K-T-A-G-R-G-H-K-G-S-F-A-R-K-G-G-G-K-I-K-A-G-F-E-G-G-Q-T-P-M-Q-R-R-L-P-K-I-G-F-R-S-K-M-A-R-D-T-A-E-V-L-S-Y-Q-L-D-K-L-D-A-G-D-V-D-F-A-A-L-R-A-A-N-L-V-P-S-R-A-K-K-A-K-I-V-L-K-G-E-L-S-K-K-F-V-L-K-G-V-A-A-T-A-G-A-K-A-A-I-E-A-A-G-G-S-V-E-E


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-I-N-K-N-I-A-R-L-R-R-A-K-S-T-R-A-H-I-R-E-L-G-V-A-R-L-S-V-L-R-T-G-Q-H-L-Y-A-Q-V-F-T-A-D-G-S-K-V-I-A-A-A-N-T-L-Q-A-D-V-K-D-G-L-K-N-G-K-N-S-D-A-A-A-K-V-G-K-L-I-A-E-R-A-K-A-A-G-I-E-K-V-A-F-D-R-S-G-Y-R-Y-H-G-R-I-K-A-L-A-D-A-A-R-E-G-G-L-Q-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-K-P-V-S-L-P-K-G-V-E-L-N-V-Q-P-G-L-V-S-V-K-G-P-K-G-T-L-T-L-P-K-P-A-G-V-E-I-A-I-D-G-G-V-A-T-L-S-A-N-D-P-S-Q-I-A-L-T-G-T-V-R-A-I-L-A-N-M-V-K-G-V-S-E-G-F-E-R-K-L-E-L-V-G-V-G-Y-R-A-A-M-Q-G-K-D-L-S-L-A-L-G-F-S-H-P-L-V-F-V-A-P-E-G-I-T-L-S-T-P-T-Q-T-E-I-V-V-Q-G-A-D-K-Q-R-V-G-E-V-A-A-K-I-R-G-F-R-P-P-E-P-Y-K-G-K-G-V-K-Y-A-G-E-V-I-I-R-K-E-A-K-K-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-T-D-P-I-A-D-L-L-V-R-I-K-N-A-A-A-V-G-K-Q-T-V-K-L-P-S-S-K-I-K-V-A-I-A-Q-V-L-K-D-E-G-Y-I-T-D-L-R-V-T-Q-A-E-N-N-K-A-E-L-E-I-V-L-K-Y-F-E-G-R-P-V-I-E-T-L-K-R-F-S-R-S-G-L-R-Q-Y-R-G-K-T-E-L-P-K-V-L-G-G-L-G-I-A-I-I-S-T-S-K-G-I-M-T-D-A-Q-A-R-E-A-G-V-G-G-E-V-L-C-F-V-A


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-T-R-L-E-K-F-Y-K-D-N-V-V-P-A-L-M-K-E-F-G-Y-T-N-P-M-E-V-P-K-L-V-K-V-T-L-N-M-G-V-G-E-A-A-T-N-K-K-I-L-E-N-A-V-A-D-M-A-K-I-S-G-Q-K-P-V-V-T-K-S-R-V-S-V-A-S-F-K-I-R-D-G-W-P-I-G-C-K-T-T-L-R-R-A-K-M-Y-E-F-L-D-R-L-I-N-I-S-L-P-R-V-R-D-F-R-G-V-S-G-R-S-F-D-G-R-G-N-F-N-M-G-V-K-E-Q-I-I-F-P-E-I-D-F-D-A-V-D-A-I-R-G-M-D-I-A-I-T-T-T-A-K-T-D-A-E-A-K-A-L-L-A-A-F-K-F-P-F-R-N


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-N-R-I-K-K-G-D-Q-V-V-I-N-T-G-K-D-K-G-K-Q-G-E-V-V-R-V-D-G-D-R-V-I-V-S-N-A-N-V-I-K-R-H-T-K-P-N-P-Q-A-G-V-A-G-G-V-V-E-R-E-A-S-I-H-I-S-N-V-N-I-V-N-P-A-T-G-K-G-E-R-V-G-F-K-V-L-E-D-G-R-K-L-R-V-F-R-S-S-G-E-A-L-D-A


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-D-N-N-E-K-Q-T-L-R-T-V-E-G-R-V-V-S-N-K-M-D-K-T-V-T-V-L-V-E-R-Q-V-K-H-A-L-Y-G-K-Y-I-K-R-S-T-K-L-H-A-H-D-A-D-N-A-C-N-E-G-D-V-V-R-V-T-E-I-A-P-M-S-K-T-K-N-W-R-V-V-E-I-V-T-R-S-A-E


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-Y-R-K-M-H-K-G-R-N-D-G-L-A-W-S-G-N-A-V-S-F-G-E-Y-G-L-K-A-T-A-H-G-Q-L-T-A-R-Q-I-E-A-A-R-R-T-I-S-R-H-V-K-K-G-G-K-M-W-I-R-V-F-P-D-K-P-I-T-K-K-P-I-E-V-R-M-G-S-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-R-M-I-Y-E-I-E-G-I-P-E-E-T-A-R-E-A-F-R-L-A-A-A-K-L-S-V-T-T-T-F-V-T-R-T-V-R


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-V-D-H-H-L-A-K-K-V-E-S-A-A-G-S-K-K-P-I-K-T-W-S-R-R-S-M-I-L-P-E-M-V-G-I-T-I-A-V-H-N-G-K-N-H-I-P-V-L-V-N-E-N-M-V-G-H-K-L-G-E-F-A-V-T-R-T-F-K-G-H-G-G-D-K-K-S-G-R


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-S-N-E-K-I-F-S-V-L-R-A-P-R-V-S-E-K-T-A-R-L-Q-E-I-S-N-Q-Y-V-F-E-V-S-N-E-A-T-K-A-D-V-K-A-A-V-E-Q-L-F-D-V-K-V-K-A-V-N-V-V-N-V-K-G-K-S-K-S-F-R-N-R-A-G-N-R-G-N-W-R-K-A-Y-V-R-L-V-D-G-Q-S-I-D-V-T-A-K-A


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-E-Q-K-I-R-I-R-L-K-A-F-D-H-R-L-I-D-R-S-A-S-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-K-I-E-R-Y-T-I-L-V-S-P-H-A-D-K-D-A-R-D-Q-Y-E-T-R-T-H-K-R-V-L-D-I-V-D-P-N-D-K-T-V-D-A-L-M-K-L-E-L-A-A-G-V-D-V-Q-I-K-L-T


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-G-S-T-P-Q-R-T-V-L-P-D-P-K-H-G-S-E-T-I-A-R-F-I-N-M-V-M-Q-S-G-K-K-S-V-A-E-K-I-V-Y-G-A-M-D-V-I-G-E-K-N-P-N-A-I-E-L-V-Q-K-A-L-D-N-V-A-P-A-V-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-S-S-R-R-M-A-L-A-M-R-W-L-I-D-S-A-R-K-R-G-E-N-T-M-P-R-K-L-A-A-E-L-L-D-A-S-E-S-R-G-G-A-I-K-K-R-E-E-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-L-T-N-E-Q-I-V-D-A-I-A-E-K-S-L-M-E-V-M-E-L-V-K-A-I-E-E-K-F-G-V-S-A-A-A-P-V-A-A-A-A-A-G-P-A-A-V-V-E-E-Q-T-E-F-N-V-V-L-T-N-C-G-T-N-K-V-G-V-I-K-A-V-R-A-V-T-G-L-G-L-K-E-A-K-D-L-T-E-A-G-G-M-L-K-E-G-A-S-K-D-E-A-E-K-I-K-K-E-L-T-E-A-G-A-T-V-E-I-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-S-Q-K-Q-E-V-V-A-E-L-A-D-I-A-A-K-A-H-S-L-I-A-A-E-Y-A-G-T-T-V-S-Q-M-T-A-M-R-K-Q-A-R-E-T-G-V-F-L-K-V-V-K-N-T-L-A-A-R-A-V-E-G-T-D-F-A-V-A-A-D-K-L-V-G-P-L-L-Y-A-F-S-M-E-E-P-G-A-A-G-R-L-I-K-E-F-A-K-S-N-D-K-L-Q-A-K-V-V-S-I-G-G-E-L-F-P-A-G-H-V-D-V-L-A-S-L-P-T-R-D-Q-A-L-A-M-L-A-R-V-L-S-E-P-A-A-M-F-A-R-A-V-K-A-V-G-D-K-Q-G-G-G-D-E-A-A-A-P-V-A-E-T-A-E-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-T-A-F-I-K-L-Q-V-K-A-G-Q-A-N-P-A-P-P-V-G-P-A-L-G-Q-R-G-L-N-I-M-E-F-C-K-A-F-N-A-A-T-S-K-L-E-P-G-L-P-T-P-V-I-I-T-A-Y-S-D-R-T-F-T-F-V-T-K-S-T-P-A-S-V-L-L-K-K-A-A-G-V-S-S-G-S-K-R-P-N-T-D-K-V-G-K-V-T-R-K-Q-L-E-E-I-A-K-V-K-E-A-D-L-T-A-A-E-L-E-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-T-V-E-G


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-A-L-R-L-I-V-G-L-G-N-P-G-P-E-H-A-Q-T-R-H-N-A-G-F-R-F-V-D-A-L-I-E-R-S-G-A-R-W-A-L-D-S-K-L-F-G-E-T-A-K-V-E-V-A-G-Q-P-V-W-L-L-K-P-A-T-F-M-N-L-S-G-K-S-I-T-A-A-L-R-F-W-K-I-E-P-E-H-L-L-V-A-H-D-E-L-D-L-A-P-G-T-A-R-L-K-F-D-G-G-H-G-G-Q-N-G-L-R-D-T-I-R-L-L-G-H-G-K-F-H-R-L-R-V-G-I-G-H-P-G-H-K-D-R-V-V-P-W-V-L-G-R-A-G-R-E-D-D-A-A-I-G-A-A-V-D-A-A-I-D-V-L-P-L-A-M-E-G-N-F-N-E-A-M-K-R-L-H-T-E-K-K


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-S-K-P-G-G-H-S-R-H-G-R-R-D-G-I-D-P-V-L-R-S-R-A-R-R-R-A-L-Q-A-V-Y-A-W-Q-I-S-G-G-F-A-K-Q-V-I-A-Q-F-A-H-E-Q-A-H-E-V-A-D-L-A-Y-F-E-N-L-V-E-G-V-L-S-N-R-A-E-L-D-T-A-L-T-P-Y-L-D-R-S-V-E-E-V-D-A-I-E-R-A-V-L-R-L-A-A-Y-E-L-L-Y-R-Q-D-V-P-Y-R-V-V-I-N-E-A-I-E-T-A-K-R-F-G-S-E-H-G-H-T-Y-V-N-G-V-L-D-R-A-A-V-E-W-R-K-V-E-S-G-A-S-G-A


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-Q-H-N-D-T-R-V-I-D-S-R-V-S-E-D-G-T-T-I-R-R-R-R-E-C-E-A-C-G-E-R-F-S-T-L-E-T-I-E-L-K-L-P-T-V-V-K-S-D-G-G-R-E-A-F-D-A-R-K-L-R-T-S-F-D-R-A-L-Q-K-R-P-V-A-E-E-Q-I-E-A-A-V-R-A-V-V-H-Q-L-R-M-S-G-E-R-E-V-G-S-L-R-V-G-E-Y-V-M-V-E-L-R-K-L-D-H-V-G-Y-V-R-F-A-S-V-Y-R-S-F-Q-D-V-A-D-F-R-E-E-I-E-K-L-E-R-E-L-P-V-G-S-E-Q-L-P-L-L-E-A-A-L-E-R-A-G-K-P-G-K-R


### FUNCTION Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'--3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism ### SEQUENCE -M-E-T-L-R-Y-R-F-D-G-Q-R-G-A-R-A-G-L-E-H-A-L-V-G-V-V-A-S-G-N-L-E-V-L-V-E-R-V-P-L-E-G-A-M-E-I-D-I-L-T-A-A-R-G-F-G-A-I-W-Q-A-V-L-D-D-F-A-A-R-H-P-L-R-D-V-R-I-S-I-N-D-V-G-A-T-P-A-V-V-S-L-R-L-E-Q-A-L-D-V-L-Q-G-A-D-A


### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-T-L-V-S-L-P-T-A-A-P-A-P-D-Y-Q-S-I-D-R-P-L-N-F-S-V-A-A-A-A-K-V-R-E-L-I-Q-E-E-G-N-A-D-L-A-L-R-V-Y-I-Q-G-G-G-C-S-G-F-Q-Y-G-F-E-F-D-E-N-R-A-E-D-D-L-A-V-A-T-D-G-V-T-L-L-V-D-P-L-S-L-Q-Y-L-M-G-A-E-V-D-Y-T-E-S-L-T-G-A-Q-F-V-I-R-N-P-N-A-K-T-T-C-G-C-G-S-S-F-S-V


### FUNCTION Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA ### SEQUENCE -M-L-V-L-L-N-K-P-Y-G-V-L-S-Q-F-S-D-R-S-Q-P-P-K-R-T-L-A-E-F-G-L-P-P-D-V-Y-A-A-G-R-L-D-H-D-S-E-G-L-L-V-L-T-D-D-G-A-L-A-H-R-L-T-D-P-R-H-K-Q-P-K-T-Y-W-V-Q-V-E-G-A-P-Q-A-E-H-L-Q-A-L-R-D-G-V-A-L-N-D-G-P-T-R-P-A-Q-V-R-M-L-D-P-A-P-Q-L-W-P-R-D-P-P-V-R-V-R-K-T-V-P-D-A-W-L-E-L-Q-I-T-E-G-R-N-R-Q-V-R-R-M-T-A-A-V-G-L-P-T-L-R-L-V-R-V-A-I-G-D-W-R-L-D-A-L-A-P-G-Q-W-R-A-E-A-T-T-N-A-R-P-S-R-S-R-R


### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-D-E-I-L-N-G-A-A-A-P-A-D-A-A-A-G-P-A-F-T-I-E-K-I-Y-V-K-D-V-S-F-E-S-P-N-A-P-A-V-F-N-D-A-N-Q-P-E-L-Q-L-N-L-N-Q-K-V-Q-R-L-N-D-N-A-F-E-V-V-L-A-V-T-L-T-C-T-A-G-G-K-T-A-Y-V-A-E-V-Q-Q-A-G-V-F-G-L-V-G-L-D-P-Q-A-I-D-V-L-L-G-T-Q-C-P-N-I-L-F-P-Y-V-R-T-L-V-S-D-L-I-Q-A-G-G-F-P-P-F-Y-L-Q-P-I-N-F-E-A-L-Y-A-E-T-L-R-Q-R-Q-N-E-G-T-S-L-A-D-S-E-P-A-G-N-A


### FUNCTION Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in Mjannaschii 16S rRNA It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3- ### SEQUENCE -M-N-Q-T-K-S-R-D-I-P-L-Y-I-Y-H-A-G-Q-C-D-P-K-K-C-T-G-R-K-M-A-R-F-E-L-A-R-L-Y-D-R-I-S-R-L-P-R-S-A-I-L-L-D-P-M-A-E-K-A-L-S-P-A-D-D-P-K-K-G-I-I-V-L-D-C-S-W-E-E-V-E-R-V-F-P-E-L-E-K-L-N-L-E-H-R-A-L-P-Y-M-L-A-G-N-P-V-N-F-G-R-P-F-K-L-N-S-A-E-A-F-A-A-A-L-Y-I-L-G-Y-K-E-Q-A-E-K-V-M-S-K-F-N-W-G-H-S-F-L-E-L-N-R-E-P-L-E-E-Y-S-T-A-K-N-S-T-E-I-V-E-I-Q-S-H-Y-I


### FUNCTION Transcriptional regulator ### SEQUENCE -M-G-K-K-L-M-R-I-G-I-S-L-P-G-E-L-L-D-K-F-D-K-T-L-M-K-R-G-Y-S-S-R-S-E-G-I-R-D-A-I-R-T-Y-N-Q-H-Y-E-W-M-K-Q-I-R-G-S-R-S-A-T-I-S-I-V-Y-D-C-S-K-K-G-V-T-S-T-L-A-E-I-Q-H-E-Y-V-D-M-I-S-S-S-V-H-F-H-M-E-E-D-L-C-F-E-V-I-I-L-R-G-E-G-E-Q-I-V-D-L-A-Q-R-I-L-S-I-K-G-V-K-H-L-R-L-T-T-V-P-E-E-K-N-E


### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-K-R-L-L-P-S-L-R-A-K-K-R-Y-L-A-F-E-L-I-S-E-E-P-A-S-R-S-D-I-V-K-E-V-M-S-S-A-S-S-L-L-G-D-V-T-T-S-D-C-D-I-R-V-L-G-F-E-N-G-K-G-I-I-Q-C-S-H-T-K-V-K-Q-T-R-A-S-L-A-A-L-T-R-I-N-G-K-R-A-T-L-H-V-L-G-V-S-G-T-V-K-R-A-T-E-K-F-L-Q-D-E-G-V-F-S-S


### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-G-D-V-A-A-K-L-K-I-M-P-E-S-V-D-T-D-L-V-G-L-K-E-N-L-K-N-V-I-P-A-G-A-Q-L-H-G-D-I-V-E-E-P-I-A-F-G-L-K-A-L-I-V-T-L-I-V-N-D-E-E-G-G-T-E-P-A-E-E-A-F-A-K-V-S-G-V-E-N-V-Q-V-L-E-A-Y-R-I


### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-R-K-R-R-E-G-T-A-N-N-S-P-T-P-E-V-T-R-V-R-T-P-R-K-E-N-H-E-V-L-A-T-V-G-S-L-L-G-S-K-R-V-N-L-Q-C-M-D-G-V-V-R-M-G-R-I-P-G-S-K-N-K-K-M-W-I-R-E-G-D-I-V-I-A-T-P-W-E-I-Q-D-S-K-A-D-V-I-W-K-Y-T-R-P-Q-I-E-W-L-E-R-K-G-Y-L-K


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-I-A-C-E-I-F-E-Q-V-K-V-T-A-E-A-H-G-A-T-E-V-K-H-V-T-L-Q-M-G-R-L-S-H-T-N-P-E-Q-L-S-F-C-F-K-T-L-A-E-G-S-I-A-E-N-A-D-L-I-V-E-M-V-P-P-T-L-E-C-E-C-G-Y-T-G-T-I-D-Q-E-R-I-R-E-S-N-E-L-T-S-E-L-L-A-Y-I-A-A-M-D-C-P-V-C-G-K-Q-A-H-I-A-G-G-R-E-L-I-I-K-S-I-E-I-E-T-E-N-E-N-E-S-Q-R


### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-A-K-G-K-Y-A-A-N-I-L-K-Q-T-R-K-D-A-R-W-K-D-T-Y-Y-G-R-R-V-L-G-L-N-V-K-A-D-P-L-G-G-A-P-Q-G-R-G-I-V-L-E-K-V-G-V-E-A-K-Q-P-N-S-A-I-R-K-C-V-R-I-Q-L-I-K-N-G-R-Q-V-T-A-F-C-P-G-D-G-A-V-N-F-I-D-E-H-D-E-V-T-V-E-R-I-G-G-R-M-G-G-A-M-G-D-I-P-G-V-R-F-K-V-I-A-V-N-N-V-S-L-N-Q-L-V-I-G-R-L-E-K-P-R-R


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center ### SEQUENCE -M-I-F-L-Y-K-I-F-G-K-W-D-P-T-E-V-E-V-R-D-L-G-I-K-R-Y-V-S-L-A-P-V-I-V-P-H-S-S-G-K-H-A-R-Q-Q-F-N-K-S-E-I-S-I-V-E-R-L-A-N-N-L-M-R-T-E-T-N-T-G-K-K-Q-V-T-L-R-A-V-E-E-A-F-D-I-I-N-R-K-T-Q-Q-N-P-I-Q-I-L-V-D-A-I-A-N-A-G-P-R-E-E-V-V-R-L-K-Y-G-G-I-S-V-P-K-A-V-D-T-A-P-Q-R-R-V-D-T-A-L-R-Y-I-S-M-G-T-N-A-A-A-F-K-S-K-R-S-V-A-E-C-L-A-T-E-L-I-G-A-A-N-R-D-T-K-S-F-S-I-N-R-K-D-A-K-E-R-V-A-K-A-A-R


### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-E-S-T-I-T-I-E-N-V-V-A-S-T-R-L-A-E-D-F-D-L-E-K-M-M-E-S-G-L-E-G-A-E-Y-N-K-V-K-F-P-G-L-V-Y-R-I-N-N-P-K-A-A-F-L-I-F-T-S-G-K-V-V-C-T-G-S-K-S-I-G-N-A-H-A-A-I-I-N-L-A-N-T-L-K-S-I-C-C-E-K-I-D-L-E-P-D-V-R-V-Q-N-I-V-A-S-A-D-L-K-T-N-L-N-L-N-T-I-A-I-A-F-G-L-E-N-V-E-Y-E-P-E-V-F-P-G-L-I-Y-R-V-E-A-P-K-V-V-V-L-V-F-S-S-G-K-L-V-I-T-G-G-K-C-P-E-D-C-E-E-G-L-R-I-V-K-T-E-F-D-N-L-G-L-L-Y


### FUNCTION Located on the platform of the 30S subunit ### SEQUENCE -M-A-D-M-K-W-A-V-A-H-I-K-S-S-F-N-N-T-I-I-T-V-T-D-I-T-G-A-E-T-I-A-K-S-S-G-G-M-V-V-K-A-A-R-D-E-S-S-P-Y-T-A-M-Q-M-A-G-Q-L-A-D-Q-L-R-D-K-G-I-N-G-I-H-I-R-V-R-A-P-G-G-N-K-Q-R-S-P-G-P-G-A-Q-A-A-I-R-A-F-A-R-A-G-I-R-I-G-R-I-E-D-V-T-P-V-P-H-D-G-T-R-P-K-G-G-R-R-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-L-H-A-L-Q-W-R-K-Y-M-A-E-E-N-N-N-E-E-L-R-H-L-V-R-I-M-N-T-D-L-K-G-A-K-P-V-E-Y-A-L-T-G-L-P-G-I-G-R-R-T-A-I-L-I-A-K-G-A-G-V-D-P-T-A-T-L-G-Y-L-P-D-E-E-V-A-K-L-D-A-A-I-G-K-F-E-E-I-V-P-S-W-M-L-N-R-Q-K-D-L-T-T-G-Q-D-K-H-L-L-G-T-D-I-L-L-T-F-R-E-D-I-N-N-L-K-K-V-R-A-Y-R-G-L-R-H-E-R-G-L-K-V-R-G-Q-R-T-K-S-T-G-R-R-G-S-T-V-G-V-S-R-K-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-D-I-K-K-F-R-G-S-R-T-C-G-G-G-T-H-K-N-R-R-G-A-G-N-R-G-G-R-G-K-A-G-G-C-K-H-H-F-V-R-A-M-M-R-G-Y-S-Y-G-K-H-G-F-K-R-P-V-E-V-S-K-D-I-S-I-V-N-V-G-E-L-D-E-L-A-P-Y-L-V-E-E-G-L-A-E-V-K-D-G-A-Y-H-I-N-L-E-N-L-G-I-E-K-V-L-G-S-G-R-V-T-K-N-L-V-V-T-S-E-E-F-S-A-S-A-R-E-K-I-E-N-A-G-G-S-C-I-D-A-E


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-T-G-P-R-Y-K-V-P-F-R-R-R-R-E-G-R-T-N-Y-H-L-R-L-K-L-L-L-S-G-Q-D-R-V-V-V-R-K-S-A-R-N-V-Q-I-Q-L-L-A-P-T-P-E-G-D-I-T-Y-S-S-A-V-S-S-E-L-A-K-Y-G-Y-T-G-A-T-G-N-T-T-A-A-Y-L-T-G-L-L-F-G-L-K-S-L-Q-K-G-Y-E-G-G-I-L-D-I-G-L-Q-A-S-S-A-G-S-R-V-Y-A-A-L-K-G-I-V-D-S-G-F-E-I-P-C-S-S-D-V-F-P-S-D-E-R-I-R-G-E-H-I-A-E-Y-R-E-E-S-S-D-L-P-E-Q-F-E-A-T-K-E-K-I-F-A-E-F-S


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-V-K-E-I-A-R-T-I-E-I-P-E-G-V-S-V-S-L-S-Q-D-V-F-T-A-K-G-P-K-G-T-V-E-R-T-F-W-Y-P-G-I-K-I-E-V-R-E-G-E-V-V-V-D-A-E-S-S-R-K-E-Q-K-A-M-V-G-T-F-A-S-H-L-K-N-L-I-I-G-V-S-E-G-F-E-C-K-M-N-I-V-Y-A-H-F-P-M-Q-V-K-V-E-G-K-T-L-V-I-G-N-F-L-G-E-K-K-P-R-I-A-K-I-L-G-E-T-K-V-K-V-S-G-N-E-I-V-V-S-G-I-N-K-E-D-V-G-Q-T-A-A-N-I-E-Q-K-T-K-I-K-R-F-D-P-R-I-F-Q-D-G-I-Y-I-V-Q-K-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-L-L-D-P-L-A-N-A-L-S-T-I-K-N-A-E-A-I-G-K-S-S-C-I-V-R-P-A-S-K-N-I-G-N-V-L-K-V-M-Q-D-L-G-Y-I-G-D-F-E-F-I-D-D-G-K-A-G-I-Y-S-V-T-L-V-G-R-I-N-K-C-G-A-I-K-P-R-Y-S-V-G-T-G-S-F-E-R-W-E-K-Q-F-L-P-A-K-N-F-G-A-L-I-L-T-T-S-S-G-V-M-S-Q-Y-E-A-R-D-K-K-I-G-G-Q-L-L-A-Y-V-Y


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-T-D-S-I-D-K-S-G-R-G-V-N-E-C-K-R-C-G-R-K-Q-G-L-V-R-K-Y-D-I-Y-L-C-R-H-C-F-R-E-I-A-H-E-M-G-F-E-K-Y-S


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-N-P-M-R-T-P-M-V-E-K-V-I-V-H-M-G-V-G-E-S-G-Q-H-L-V-N-A-E-E-I-L-K-T-I-T-G-Q-E-V-V-R-C-F-A-K-R-T-L-P-A-F-S-I-K-K-N-E-P-I-G-C-K-V-T-L-R-G-Q-R-A-Q-E-F-L-G-T-S-F-E-I-I-E-K-T-L-S-R-A-Q-F-D-S-L-G-N-V-S-F-G-I-E-E-H-T-D-F-P-G-M-R-Y-D-P-N-I-G-V-F-G-M-D-V-T-V-V-L-K-R-P-G-E-R-I-C-K-R-R-I-A-T-R-K-I-P-T-D-H-R-V-T-V-D-D-A-I-A-F-L-N-E-S-Y-G-V-E-V-M


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-E-V-I-E-M-V-S-K-Q-P-R-K-Q-R-K-A-R-Y-T-A-P-L-H-I-R-Q-K-F-M-G-A-R-L-S-E-A-L-A-K-Q-Y-G-T-R-S-A-A-V-I-T-G-D-T-V-K-I-M-R-G-D-F-K-G-T-E-G-K-V-Q-S-V-S-L-M-D-G-T-I-A-V-D-G-V-I-S-T-K-V-D-G-T-E-V-P-R-P-I-N-P-S-N-V-M-I-T-K-L-E-M-K-D-G-R-R-A-S-S-I-K-K


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-K-G-I-R-S-N-I-P-R-A-L-N-A-G-A-Q-I-A-C-V-D-N-T-G-A-K-V-V-E-I-I-S-V-K-K-Y-R-G-V-K-N-R-M-P-C-A-G-I-G-D-M-C-V-V-S-V-K-K-G-T-P-E-M-R-K-Q-I-L-L-A-V-V-V-R-Q-K-Q-E-F-R-R-P-D-G-L-H-V-S-F-E-D-N-A-M-V-I-T-D-E-D-G-I-P-K-G-T-D-I-K-G-P-V-A-R-E-V-A-E-R-F-P-K-I-G-T-T-A-S-I-I-V


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-R-D-I-G-L-N-I-P-A-P-S-E-E-C-D-D-A-Y-C-P-F-H-G-T-L-P-V-R-G-Q-I-L-V-G-T-V-V-S-S-K-M-D-N-T-V-V-I-E-R-Q-Y-M-K-M-V-S-K-Y-Q-R-Y-E-K-R-R-S-K-I-H-A-H-N-P-A-C-I-S-A-K-V-G-D-I-V-T-I-V-E-C-R-P-I-S-K-T-K-S-F-V-V-V-K-A-E-V-P-K


### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-R-S-K-V-E-I-L-P-S-T-L-I-F-H-E-L-I-G-L-E-I-K-V-S-N-S-T-N-P-S-L-I-G-I-R-G-R-V-I-N-E-T-K-N-M-L-V-V-E-N-S-E-S-R-E-L-K-I-P-K-A-D-S-E-F-V-F-R-I-P-A-E-L-S-E-K-G-R-R-S-D-I-F-V-K-I-Q-G-N-L-L-L-S-Q-P-E-N-R-I-K-N-I-K-K-L-R-K-W-G


### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-A-R-I-N-Y-S-I-N-A-D-P-E-N-T-S-K-A-M-G-S-E-L-H-I-S-P-K-K-S-R-E-V-C-C-K-I-K-G-M-K-A-S-E-A-R-K-F-L-E-D-V-I-A-M-K-Q-A-V-P-F-K-R-H-S-E-G-A-G-H-R-K-G-P-M-A-G-G-R-Y-P-V-S-A-S-K-E-I-L-K-V-L-K-N-A-E-S-N-A-E-Y-K-G-L-E-P-A-N-M-Y-I-I-H-A-A-I-Q-R-G-R-V-I-H-G-F-M-P-R-A-R-G-R-A-S-P-K-D-T-E-T-V-N-I-E-M-I-L-S-E-V-R


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-K-K-S-S-S-R-L-P-K-R-K-G-E-Y-T-Y-R-G-K-T-V-S-E-L-Q-E-L-S-L-E-E-F-A-E-L-L-P-S-R-E-R-R-S-I-K-R-G-F-T-D-G-Q-K-K-V-L-H-E-F-K-E-G-K-K-I-R-T-H-H-R-D-M-I-I-L-P-E-M-I-G-I-A-I-E-V-H-N-G-K-E-F-V-N-V-E-L-Q-P-E-M-I-G-H-R-F-G-E-F-A-P-T-R-S-R-V-N-H-G-S-A-G-V-G-A-T-R-S-S-K-F-V-P-L-K


### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-S-S-I-N-Y-P-F-V-T-E-K-A-M-M-L-L-D-E-N-K-L-Q-F-I-V-D-T-R-S-N-K-K-Q-I-V-E-D-V-E-K-L-Y-G-F-K-V-K-A-V-R-T-M-T-T-M-K-G-T-K-K-A-V-L-A-F-E-E-P-E-A-A-H-E-I-A-T-R-I-G-L-M


### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-F-P-G-M-G-G-V-G-G-R-G-M-N-P-A-K-M-K-Q-M-M-K-Q-M-G-I-D-V-K-E-L-K-D-V-E-E-V-V-I-K-T-A-D-S-N-I-V-I-E-N-A-N-V-T-I-M-T-V-Q-G-S-E-T-Y-Q-I-V-G-D-V-K-E-V-P-K-S-L-E-I-P-A-E-D-I-K-L-V-M-E-Q-T-G-V-S-E-E-E-A-R-N-A-L-K-N-S-N-G-D-L-A-E-A-I-V-A-L-S-S-A


### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-T-L-A-D-L-K-K-P-T-S-R-A-S-P-S-T-E-E-T-V-T-R-V-R-T-P-R-R-E-N-N-E-I-L-A-T-V-E-S-L-L-G-A-N-R-L-R-L-R-C-M-D-G-V-V-R-M-G-R-I-P-G-S-M-K-K-K-A-W-I-R-E-G-D-V-V-I-A-V-P-W-E-F-Q-N-E-K-A-D-V-I-W-K-Y-T-R-P-Q-V-D-W-L-E-R-K-G-Y-L-K-G


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-I-V-K-P-I-G-E-R-V-L-L-K-H-Q-K-K-E-E-V-T-K-G-G-I-Y-I-P-E-S-A-R-Q-E-K-K-E-G-I-V-V-A-V-G-T-F-E-D-G-K-E-L-P-L-K-K-D-D-H-V-I-Y-G-G-Y-Q-A-D-E-I-E-I-D-D-E-K-Y-I-F-V-D-F-K-D-I-L-A-T-V-V-E-E