### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-A-E-V-E-S-F-Q-L-D-H-T-K-V-L-A-P-Y-V-R-L-I-G-S-E-T-G-P-K-G-D-V-I-T-N-F-D-V-R-F-V-Q-P-N-A-N-A-I-G-M-A-A-L-H-T-I-E-H-S-M-A-S-L-I-R-D-R-I-D-G-M-I-D-F-S-P-F-G-C-Q-T-G-F-H-M-I-M-W-G-E-H-S-S-E-E-I-A-K-V-I-K-S-S-L-E-E-L-A-S-D-E-F-G-W-D-N-V-P-G-V-A-E-K-E-C-G-N-Y-R-N-H-S-L-F-G-A-K-E-W-S-K-K-I-L-S-E-G-I-S-T-D-P-Y-E-R-K-V-I


### FUNCTION In complex with DhaQ, upon activation by dihydroxyacetone, activates transcription of the dhaKLM operon Binds the inverted repeat sequence 5'-GGACACATNATTTGTCC-3' located upstream of and partially overlapping with the -35 promoter sequence of the dhaKLM operon promoter ### SEQUENCE -M-S-A-F-F-L-N-M-K-K-S-I-I-T-Q-K-I-I-A-K-A-F-K-D-L-M-Q-S-N-A-Y-H-Q-I-S-V-S-D-I-M-Q-T-A-K-I-R-R-Q-T-F-Y-N-Y-F-Q-N-Q-E-E-L-L-S-W-I-F-E-N-D-F-A-E-L-I-N-D-N-S-D-Y-Y-G-W-Q-N-E-L-L-L-L-L-R-Y-L-D-E-N-Q-I-F-Y-Q-K-I-F-V-I-D-K-N-F-E-H-F-F-L-I-Q-W-E-N-L-L-D-K-V-I-F-D-Q-E-K-K-S-D-Y-H-W-S-D-L-E-K-S-F-I-C-R-Y-N-A-A-A-I-C-A-I-T-R-E-S-I-I-R-G-N-S-L-E-K-L-Y-S-Q-I-V-N-L-L-L-A-Q-I-K-I-F-E-S


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-I-R-G-F-E-V-V-T-K-Y-K-N-A-G-I-N-I-P-K-R-S-T-E-H-S-A-G-Y-D-I-E-A-A-E-T-V-S-F-A-P-G-E-I-K-L-I-P-T-G-L-K-A-Y-M-Q-A-G-E-V-L-Y-M-Y-D-R-S-S-N-P-R-K-K-G-L-V-L-I-N-S-V-G-V-I-D-K-D-Y-Y-N-N-P-D-N-E-G-H-M-F-M-Q-M-R-N-F-T-D-E-E-V-V-I-E-K-G-E-R-V-V-Q-G-V-F-M-P-F-L-V-A-D-G-D-E-N-Q-E-K-E-E-R-T-G-G-F-G-S-T-G-A


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-Q-I-T-E-E-Q-V-K-H-V-A-L-L-S-K-L-E-F-S-E-N-E-V-K-S-F-T-D-T-F-G-K-I-I-D-M-V-E-M-L-D-E-V-D-G-E-G-V-P-F-T-M-N-V-A-D-N-L-N-F-M-R-E-D-V-A-E-K-G-L-D-R-E-K-L-M-A-A-V-P-E-K-E-D-G-F-I-K-V-P-A-M-L-S-D-G-G-D-A


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-F-A-R-I-L-G-L-D-V-G-T-K-T-V-G-V-S-V-S-D-L-L-G-M-T-A-Q-P-V-E-T-I-K-I-D-S-E-A-G-E-L-G-F-E-R-L-G-V-L-I-K-E-Y-K-P-E-K-V-V-L-G-L-P-K-H-M-N-G-D-E-G-I-R-A-E-A-S-R-D-Y-G-T-K-L-A-N-E-F-G-L-E-V-A-Y-Q-D-E-R-L-T-T-A-Q-A-E-K-V-L-I-D-G-G-V-R-R-K-E-R-K-K-S-I-D-K-L-A-A-V-L-I-L-Q-N-Y-L-D-A-H-A-L-K-L


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-A-I-K-K-T-Y-R-V-K-R-S-K-D-F-D-Q-I-F-S-A-K-H-S-F-A-N-K-K-F-V-V-Y-K-L-N-T-N-Q-P-H-F-R-V-G-L-S-V-S-K-K-L-G-H-A-V-L-R-N-R-I-K-R-L-L-R-H-A-I-A-E-F-K-P-Y-L-T-D-E-D-F-V-I-I-A-R-S-G-V-E-T-L-S-F-E-E-V-K-K-N-L-K-H-V-L-K-L-S-K-I-Y-V-D-G-E-N-D


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-N-M-Q-S-M-M-K-Q-A-Q-K-L-Q-K-Q-M-Q-V-S-Q-E-E-I-A-N-T-T-F-V-G-K-S-A-Q-D-L-V-T-V-E-F-S-G-D-R-T-L-K-S-L-D-I-K-P-D-V-I-D-P-E-D-P-E-T-L-Q-D-M-V-T-D-A-V-N-D-A-L-S-Q-I-E-K-V-T-E-Q-K-L-G-K-F-T-K-G-L-P-F


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-K-M-I-V-G-L-G-N-P-G-D-K-Y-E-K-T-K-H-N-M-G-F-M-A-L-D-L-L-A-K-E-L-N-V-D-F-K-E-E-K-P-F-M-S-L-V-A-S-T-F-V-N-G-E-K-L-F-L-V-K-P-L-T-F-M-N-E-S-G-R-S-V-A-P-L-L-K-Y-Y-N-I-D-E-A-D-L-T-V-M-H-D-D-L-D-S-P-V-G-R-V-R-L-R-Q-K-G-S-S-G-G-Q-N-G-I-K-S-V-I-T-H-V-G-S-Q-T-F-N-R-V-K-I-G-I-G-R-P-K-H-G-M-T-V-G-N-H-V-L-S-G-F-D-N-E-D-K-E-I-A-Q-D-G-I-F-K-A-V-D-A-M-K-F-Y-L-E-N-G-D-F-Q-K-T-M-N-K-F-N


### FUNCTION P-II indirectly controls the transcription of the glutamine synthetase gene ### SEQUENCE -M-K-K-I-E-A-I-I-K-P-F-K-L-D-D-V-R-E-S-L-S-D-V-G-I-T-G-M-T-V-T-E-V-R-G-F-G-R-Q-K-G-H-T-E-L-Y-R-G-A-E-Y-M-V-D-F-L-P-K-V-K-M-E-I-V-V-T-D-E-Q-V-D-Q-C-I-E-A-I-M-E-T-A-Q-T-G-K-I-G-D-G-K-I-F-V-Y-D-V-E-R-V-I-R-I-R-T-G-E-E-N-E-D-A-I


### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-T-T-E-T-T-T-T-K-I-I-E-A-N-E-I-M-K-L-L-P-H-R-Y-P-F-L-L-V-D-R-V-V-D-Y-E-E-G-K-W-L-K-A-V-K-N-I-S-V-N-E-P-C-F-T-G-H-F-P-E-Q-P-I-F-P-G-V-L-I-L-E-A-M-A-Q-A-T-G-V-L-A-C-K-T-Y-R-Q-L-E-N-E-I-Y-Y-F-A-A-I-D-N-A-R-F-K-R-P-V-L-P-G-D-Q-M-V-L-E-V-H-F-L-K-E-R-R-G-I-T-R-F-T-G-V-A-T-V-D-G-Q-V-V-C-E-A-E-L-M-C-A-R-R-P-A


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-V-I-P-M-V-V-E-Q-T-A-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-E-R-V-I-F-L-G-G-E-V-E-D-R-M-A-N-L-I-V-A-Q-L-L-F-L-E-S-E-D-P-E-K-D-I-N-I-Y-I-N-S-P-G-G-S-V-T-A-G-M-A-I-Y-D-T-M-Q-F-V-K-P-D-I-R-T-L-C-V-G-Q-A-C-S-M-G-A-F-L-L-A-G-G-T-A-G-K-R-I-A-L-P-S-A-R-V-M-I-H-Q-P-L-G-G-F-R-G-Q-A-S-D-I-Q-I-H-A-Q-E-I-L-K-I-K-Q-T-L-N-E-R-L-A-F-H-T-G-Q-T-I-E-R-I-E-R-D-T-D-R-D-N-F-M-S-A-E-E-A-K-A-Y-G-L-V-D-E-V-L-A-S-R


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-K-I-Q-L-I-A-V-G-T-K-M-P-N-W-V-T-M-G-F-E-E-Y-Q-R-R-F-P-K-E-M-P-F-E-L-I-E-I-P-A-G-K-R-G-K-N-A-D-I-K-R-I-L-E-Q-E-G-K-A-M-L-A-A-C-G-K-S-R-I-V-T-L-D-I-P-G-K-P-W-T-T-E-Q-L-A-T-Q-L-E-V-W-K-N-D-G-R-D-L-S-L-L-I-G-G-P-E-G-L-S-A-E-C-K-A-A-A-E-Q-S-W-S-L-S-P-L-T-L-P-H-P-L-V-R-V-V-V-A-E-S-L-Y-R-A-W-S-V-T-M-N-H-P-Y-H-R-E


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-I-E-E-R-V-K-K-I-I-V-E-Q-L-G-V-K-E-D-E-V-K-P-E-A-S-F-V-E-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-I-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-S-A-I-D-Y-V-Q-N-N-Q


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-G-M-T-V-L-A-F-D-F-G-T-K-S-I-G-C-A-V-G-Q-S-I-T-G-T-A-Q-A-L-P-A-F-K-A-Q-D-G-I-P-N-W-D-A-I-G-K-C-L-A-E-W-Q-P-D-R-V-V-V-G-L-P-L-N-M-D-G-T-E-Q-D-L-T-V-R-A-R-K-F-A-H-R-L-H-G-R-F-G-V-A-V-E-L-Q-D-E-R-L-T-T-T-E-A-R-A-E-I-F-G-R-G-G-Y-K-A-L-N-K-S-K-V-D-G-I-S-A-C-L-I-L-E-S-W-F-E-N-Q-Q-V-K


### FUNCTION A GTPase-activating protein  that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-A-R-K-K-K-T-R-R-V-S-D-I-M-P-A-R-K-V-D-K-K-V-E-L-P-K-G-K-Q-G-K-K-L-T-R-Y-E-L-D-A-K-A-R-E-D-K-K-K-K-K-R-K-G-L-A-S-G-S-R-H-S-A-T-E-N-N-N-N-H-Q-A-L-A-K-K-D-P-R-L-G-S-R-K-K-V-P-L-I-V-E-F-V-N-K-P-E-K-G-M-T-I-P-P-M-K-V-E-E-K-V-A-K-L-D-P-M-L-E-L-E-Q-L-E-N-N-E-C-L-N-Q-L-L-D-A-L-D-A-G-K-T-L-S-A-E-D-Q-Q-F-V-D-D-C-L-D-R-I-A-Q-L-M-D-E-L-G-I-S-E-D-D-D-P-E-E-D-L-L-R-T-F-E-K-I-D-I-N-Q-F-R


### FUNCTION Modulates RecA activity ### SEQUENCE -M-I-S-K-H-C-K-E-A-G-N-H-R-M-S-S-P-A-L-N-Y-V-V-G-L-L-A-R-R-E-Y-S-E-F-E-L-R-C-K-M-Q-E-K-G-F-S-E-Q-E-I-D-D-T-L-A-F-C-Q-Q-K-N-W-Q-N-D-R-R-F-A-E-N-Y-L-T-F-R-A-Q-R-G-Y-G-F-A-R-I-K-Q-E-L-Q-Q-L-K-G-I-S-S-A-L-I-S-E-A-E-Q-T-L-A-P-D-W-Q-H-H-A-L-T-V-L-R-K-K-F-P-Q-Y-A-E-I-T-D-L-K-L-K-Q-K-V-W-R-Y-M-L-S-H-G-F-K-P-E-Q-F-A-H-Y-V-G-H-T-E-Y-E-E


### FUNCTION Involved in the biogenesis of TorA Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor ### SEQUENCE -M-M-P-F-S-R-E-E-R-Q-F-V-Y-T-W-L-S-N-M-L-G-H-E-L-S-A-S-Q-L-A-Q-Y-Q-Q-G-L-F-D-D-F-F-A-F-L-T-E-Q-G-F-Q-A-Q-V-E-G-I-Q-Q-Q-L-Q-Q-L-K-T-V-E-L-A-H-L-E-L-A-A-D-Y-T-Q-L-F-L-L-D-G-S-S-S-A-L-P-Y-A-S-V-Y-L-P-E-A-Q-L-T-C-H-F-T-F-L-E-A-L-L-V-R-F-Q-L-Q-L-N-R-D-K-P-E-P-S-D-H-L-C-V-Y-L-E-L-L-R-Q-L-A-E-V-D-D-M-K-T-Y-R-Q-L-I-Q-D-A-L-L-P-W-L-L-P-F-N-D-K-V-Q-R-V-K-T-R-T-T-F-Y-Q-Q-V-V-V-L-L-I-L-L-L-Q-A-D-C-Q-N


### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-T-E-T-T-T-K-K-R-W-Y-V-L-Q-A-F-S-G-F-E-G-R-V-A-T-T-L-R-E-Y-I-K-L-H-Q-M-E-D-Q-F-G-E-V-L-V-P-T-E-E-V-V-E-N-V-A-G-K-R-R-K-S-E-R-K-F-F-P-G-Y-V-L-V-Q-M-E-M-N-D-E-T-W-H-L-V-R-S-V-P-R-V-M-G-F-I-G-G-T-A-D-K-P-A-P-I-S-Q-R-E-A-D-R-I-L-N-R-L-Q-E-S-S-E-K-P-R-H-R-K-E-F-Q-P-G-E-E-V-R-V-T-E-G-P-F-A-D-F-N-G-T-V-E-E-V-D-Y-E-K-G-R-L-K-V-S-V-S-I-F-G-R-A-T-P-V-E-L-E-F-S-Q-V-E-K-T-N


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-Q-A-Y-V-K-L-Q-V-A-A-G-M-A-N-P-S-P-P-V-G-P-A-L-G-Q-Q-G-V-N-I-M-E-F-C-K-A-F-N-A-R-T-E-S-L-E-K-G-L-P-I-P-V-V-I-T-V-Y-A-D-R-S-F-T-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-I-K-S-G-S-G-K-P-N-K-D-K-V-G-K-V-T-L-E-Q-V-R-Q-I-A-E-T-K-A-A-D-M-T-G-S-S-I-E-T-K-M-K-S-I-A-G-T-A-R-S-M-G-L-V-V-E-E


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-Q-D-K-Q-A-I-V-A-E-V-N-E-A-A-K-G-A-L-S-A-V-I-A-D-S-R-G-V-T-V-D-K-M-T-E-L-R-K-V-A-R-E-N-G-V-S-M-R-V-V-R-N-T-L-L-R-R-A-V-E-G-T-E-F-E-C-L-K-D-T-F-V-G-P-T-L-I-A-F-S-T-E-H-P-G-A-A-A-R-L-F-K-D-F-A-K-A-N-D-K-F-E-I-K-G-A-A-F-E-G-K-I-Q-D-V-E-F-L-A-T-L-P-T-Y-D-E-A-I-A-R-L-M-G-T-M-K-E-A-A-A-G-K-L-V-R-T-L-A-A-L-R-D-K-L-Q-E-A-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-L-T-N-E-Q-I-I-E-A-I-A-S-K-S-V-T-E-I-V-E-L-I-A-A-M-E-E-K-F-G-V-S-A-A-A-A-A-V-A-V-A-A-G-P-A-E-A-A-E-E-K-T-E-F-D-V-V-L-A-G-A-G-A-N-K-V-A-V-I-K-A-V-R-G-A-T-G-L-G-L-K-E-A-K-D-L-V-E-S-A-P-A-V-L-K-E-G-I-S-K-A-E-A-E-A-L-K-K-E-L-E-E-A-G-A-Q-V-E-V-K


### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-D-L-I-D-A-I-A-S-A-A-E-L-N-K-K-Q-A-K-A-A-L-E-A-T-L-E-A-I-S-G-S-L-K-A-G-E-P-V-Q-L-I-G-F-G-T-F-K-V-N-S-R-K-A-R-T-G-R-N-P-Q-T-G-A-E-I-K-I-A-A-S-K-V-P-A-F-V-A-G-K-A-L-K-D-A-V-K


### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-S-S-K-S-I-E-L-P-V-L-G-Q-V-L-R-L-N-C-P-E-E-Q-H-E-A-L-K-Q-A-A-R-E-L-D-L-R-V-S-E-M-K-E-R-T-G-I-L-Q-L-E-R-V-L-S-I-V-A-L-N-L-S-Y-E-L-L-Q-A-Q-Q-K-T-T-S-I-E-A-L-L-Q-H-R-I-Q-Q-L-D-H-S-L-E-S-I-L-T-Q-K-V-N-N


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-I-S-I-T-Q-L-L-I-I-V-A-I-V-V-L-L-F-G-T-K-K-L-R-T-L-G-S-D-L-G-E-S-V-K-G-F-K-K-A-M-A-D-D-N-K-E-K-D-A-E-F-K-S-L-S-D-D-S-E-T-T-A-K-T-E-K-A-K-D-K-E-Q-A


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-T-L-A-N-I-K-S-A-K-K-R-A-I-Q-S-E-K-R-R-Q-H-N-A-S-Q-R-S-M-M-R-T-Y-I-K-K-V-Y-A-A-V-A-A-G-D-K-S-V-A-E-K-A-F-V-E-M-Q-K-V-V-D-R-M-A-S-K-G-L-I-H-A-N-K-A-A-N-H-K-A-N-L-S-A-Q-I-K-K-L-A


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-S-V-G-Q-Q-I-I-F-I-S-S-G-A-A-L-G-A-L-S-R-W-G-L-G-L-L-L-N-P-L-F-S-A-F-S-L-G-T-L-V-A-N-Y-L-G-C-L-I-I-G-V-F-L-A-F-F-W-Q-Y-P-Q-C-S-A-E-W-R-L-F-F-V-T-G-F-L-G-S-L-T-T-F-S-T-F-S-A-E-V-I-E-N-L-I-Q-Q-K-W-L-A-G-L-M-L-A-S-G-H-L-L-G-C-L-L-F-T-A-L-G-V-F-I-W-R-Y-W-Q


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-L-F-I-F-L-L-V-A-V-L-L-L-F-Q-Y-D-F-W-F-G-K-N-G-Y-L-D-Y-K-R-T-A-Q-Q-I-A-Q-H-K-Q-E-N-E-K-L-S-Q-R-N-Q-V-V-A-A-E-I-K-D-L-K-Q-G-V-E-A-I-E-E-R-A-R-F-Q-H-D-M-V-K-P-D-E-I-F-Y-H-I-V-K-E-Q-K


### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-Q-K-I-M-I-S-D-A-A-Q-A-H-F-R-R-L-L-D-Q-Q-E-E-G-T-H-I-R-I-F-V-V-N-P-G-T-P-N-A-E-C-G-V-S-Y-C-P-P-N-A-V-E-A-T-D-T-E-M-Q-Y-A-S-F-S-A-F-V-D-E-I-S-L-P-F-L-D-E-A-E-I-D-Y-V-T-E-E-L-G-A-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-A-D-D-A-P-L-L-E-R-V-E-Y-V-I-Q-T-Q-I-N-P-Q-L-A-G-H-G-G-R-I-T-L-I-E-I-T-E-D-G-Y-A-I-L-Q-F-G-G-G-C-N-G-C-S-M-V-D-V-T-L-K-D-G-I-E-K-Q-L-L-S-L-F-P-G-E-L-Q-G-A-K-D-V-T-E-H-Q-R-G-E-H-S-Y-Y


### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-N-E-I-R-V-T-Q-T-L-D-T-L-G-L-R-C-P-E-P-V-M-L-V-R-K-H-I-R-F-L-E-E-G-D-V-L-L-V-I-A-D-D-P-A-T-T-R-D-I-P-S-F-C-Q-F-M-E-H-T-L-L-K-S-E-I-E-H-I-P-F-Q-Y-W-V-K-K-G-K


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-V-F-N-L-T-V-V-S-A-E-Q-Q-I-F-S-G-Q-V-E-S-I-Q-A-T-G-I-E-G-E-L-G-I-L-A-G-H-T-P-L-L-T-A-I-K-P-G-I-V-K-L-T-L-E-D-G-K-E-E-V-I-Y-V-S-G-G-F-L-E-V-Q-P-N-V-V-T-V-L-A-D-T-A-I-R-G-D-E-L-D-G-D-R-I-L-A-A-K-K-R-A-E-E-N-I-R-T-R-H-G-D-A-N-Y-E-M-L-A-S-K-L-S-K-E-L-A-K-L-R-A-Y-E-L-T-E-K-L-V-K-N-K-R


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-E-L-T-T-I-A-R-P-Y-A-K-A-A-F-D-F-A-I-E-Q-N-A-V-E-K-W-A-N-M-L-H-F-S-S-E-L-I-K-D-E-T-M-Q-T-F-L-K-S-S-L-S-A-S-K-L-A-D-T-V-I-S-I-C-G-E-Q-L-D-Q-Y-G-Q-N-L-I-R-L-M-A-E-N-K-R-L-E-V-L-P-A-I-Y-Q-A-F-Q-H-Y-V-E-E-H-Q-K-V-A-E-V-Q-V-I-S-A-Q-P-L-N-A-T-Q-E-Q-K-I-A-S-A-M-E-K-R-L-A-R-K-V-K-L-N-C-S-L-D-S-S-L-I-A-G-V-I-I-R-T-D-D-F-V-I-D-G-S-S-R-G-Q-L-S-R-L-A-N-E-L-Q-L


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-L-N-A-T-L-I-G-Q-L-I-A-F-A-I-F-V-A-F-C-M-K-F-V-W-P-P-I-I-K-A-I-E-E-R-Q-R-S-I-A-N-A-L-A-S-A-E-A-A-R-K-E-Q-A-D-T-K-A-L-V-E-Q-E-I-T-E-A-K-M-Q-A-Q-Q-I-I-D-L-A-N-K-R-R-N-E-I-L-E-E-V-K-V-E-A-E-A-T-K-A-K-I-I-E-Q-G-Y-A-E-V-E-A-E-R-K-R-V-Q-E-E-L-R-V-K-V-A-S-L-A-I-A-G-A-E-K-I-V-G-R-T-V-D-E-A-A-N-S-D-I-I-D-K-L-V-A-E-L


### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-L-E-I-L-D-Q-L-E-E-K-I-K-Q-A-V-E-T-I-Q-L-L-Q-L-E-I-D-E-L-K-E-K-N-N-Q-S-Q-Q-A-N-D-A-L-R-S-E-N-E-Q-L-K-S-E-H-Q-N-W-Q-E-R-L-R-S-L-L-G-K-I-D-N-V


### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-D-S-N-K-I-T-F-F-T-R-F-E-Q-D-I-L-A-G-R-K-T-I-T-I-R-D-K-S-E-S-S-F-Q-P-N-Q-I-L-A-V-Y-T-N-E-T-D-R-F-F-A-N-I-K-V-L-S-V-T-P-I-H-F-E-A-L-S-E-A-H-A-Q-Q-E-N-M-T-L-P-E-L-R-Q-V-I-K-E-I-Y-P-Q-E-D-C-F-W-V-I-A-F-E-L-V-D


### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-S-A-F-S-E-I-S-P-Q-Q-A-W-Q-L-V-Q-Q-H-A-A-A-L-L-D-I-R-N-E-T-H-F-A-L-A-H-P-A-Q-A-F-H-L-S-H-Q-S-Y-G-E-F-E-M-Q-Y-E-D-D-H-P-V-I-V-I-C-Y-H-G-V-S-S-R-G-A-A-M-Y-L-I-E-Q-G-Y-T-Q-V-Y-S-V-T-G-G-F-E-A-W-E-R-D-G-L-P-I-E-R-I-G


### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-E-E-N-Q-V-N-A-A-D-T-Q-A-T-Q-Q-P-V-L-Q-I-Q-R-I-Y-V-K-D-V-S-F-E-A-P-N-L-P-H-I-F-Q-Q-D-W-E-P-K-L-S-F-D-L-S-T-E-A-K-Q-V-G-D-D-L-Y-E-V-C-L-N-I-S-V-E-T-T-M-E-S-S-G-D-V-A-F-I-C-E-V-K-Q-A-G-V-F-T-I-S-G-L-E-E-M-Q-M-A-H-C-L-T-S-Q-C-P-N-M-L-F-P-Y-A-R-E-L-V-S-S-L-V-N-R-G-T-F-P-A-L-N-L-S-P-V-N-F-D-A-L-F-M-D-Y-L-Q-R-Q-E-Q-A-E-Q-T-T-E-E-E-N-K-D-V-H


### FUNCTION Catalyzes the decarboxylation of oxaloacetate coupled to Na translocation ### SEQUENCE -M-T-N-A-E-L-L-Q-E-G-I-N-L-M-F-A-G-V-G-F-V-M-L-F-L-F-I-L-I-Y-A-I-E-F-M-S-K-L-V-N-T-Y-F-P-E-P-V-K-A-P-S-T-K-P-I-Q-A-E-N-H-D-L-E-R-L-R-P-V-I-V-A-A-I-A-H-H-R-R-Q-Q-G-L-K


### FUNCTION One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA It is important during the early stages of 50S assembly It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-E-L-Q-V-V-G-A-N-A-L-T-V-S-E-T-T-F-G-R-E-F-N-E-A-L-I-H-Q-V-V-V-A-Y-A-A-G-A-R-Q-G-S-R-A-Q-K-T-R-A-E-V-S-G-S-G-K-K-P-W-R-Q-K-G-T-G-R-A-R-S-G-D-I-K-S-P-I-W-R-S-G-G-V-T-F-A-A-K-P-Q-D-H-S-Q-K-V-N-K-K-M-Y-R-G-A-I-K-S-I-L-S-E-L-V-R-Q-D-R-L-I-V-V-E-K-F-E-V-E-A-P-K-T-K-V-L-V-Q-K-L-K-E-L-A-L-E-D-V-L-I-I-T-A-S-L-D-E-N-L-F-L-A-A-R-N-L-Y-K-V-D-V-R-D-V-Q-G-I-D-P-V-S-L-I-A-F-D-K-V-V-V-T-V-D-A-V-K-Q-I-E-E-M-L-A


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-I-Q-Q-E-R-L-L-K-V-L-K-A-P-H-V-S-E-K-A-T-N-N-A-E-K-S-N-T-I-V-F-K-V-A-L-D-A-N-K-V-E-I-A-N-A-V-E-Q-L-F-E-V-K-V-D-S-V-R-T-V-V-V-K-G-K-T-K-R-H-G-A-R-M-G-R-R-S-D-W-K-K-A-Y-V-T-L-Q-E-G-Q-S-L-D-F-V-E-G-A-E


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-I-A-K-H-R-Y-A-R-T-S-A-Q-K-A-R-L-V-A-D-L-I-R-G-K-K-V-A-A-A-L-E-I-L-T-F-T-N-K-K-A-A-A-L-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-D-G-A-D-I-D-D-L-K-V-A-K-I-F-V-D-E-G-P-S-M-K-R-V-M-P-R-A-K-G-R-A-D-R-I-L-K-R-T-S-H-I-T-V-V-V-S-D-R


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-V-H-K-G-R-N-R-G-I-A-A-G-T-E-V-S-F-G-T-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-A-V-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-E-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-V-L-Y-E-M-D-G-V-S-E-E-I-A-R-N-A-F-A-L-A-A-A-K-L-P-I-K-T-T-F-V-T-K-T-V-M


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-T-D-K-I-R-S-V-Q-G-K-V-V-S-D-K-M-D-K-S-F-V-V-A-I-E-R-K-V-K-H-P-L-Y-G-K-F-I-R-R-T-T-K-L-H-V-H-D-E-N-N-E-A-K-L-G-D-I-V-E-I-K-E-C-R-P-L-S-K-T-K-S-W-T-L-V-R-V-V-E-K-A-V-V-A


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-Q-N-D-E-V-I-V-L-A-G-K-S-K-G-K-R-G-K-V-T-Q-V-L-P-N-G-K-V-I-V-E-G-V-N-I-I-T-K-H-E-K-P-V-P-A-L-G-K-E-G-G-L-V-K-K-E-A-A-I-D-V-S-N-V-A-I-F-N-P-K-T-N-K-A-D-R-V-G-F-R-F-E-D-G-K-K-V-R-F-F-K-S-N-N-E-I-I


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-R-D-Q-V-V-N-E-L-K-D-K-F-N-Y-K-S-V-M-Q-V-P-R-I-E-K-I-T-L-N-M-G-V-G-E-A-L-T-D-K-K-L-L-D-N-A-V-A-D-L-A-A-I-S-G-Q-K-P-L-I-T-K-A-R-K-S-V-A-G-F-K-I-R-Q-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-E-F-F-E-R-L-I-T-I-A-V-P-R-I-R-D-F-R-G-L-S-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-Y-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-T-A-K-S-D-E-E-G-Q-A-L-L-A-A-F-N-F-P-F-R-K


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-Q-S-M-K-A-R-D-V-K-R-V-K-L-A-E-K-F-Y-A-K-R-A-E-L-K-Q-I-I-S-D-V-N-A-S-D-E-D-R-W-N-A-V-L-K-L-Q-T-L-P-R-D-S-S-P-S-R-Q-R-N-R-C-R-Q-T-G-R-P-H-G-V-L-R-K-F-G-L-S-R-I-K-V-R-E-A-A-M-R-G-E-I-P-G-L-K-K-A-S-W


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-A-D-M-L-T-R-I-R-N-G-Q-A-A-N-K-V-A-I-S-M-P-S-S-K-L-K-V-A-I-A-N-V-L-A-E-E-G-Y-I-E-S-V-K-V-L-D-G-V-K-P-E-L-E-I-T-L-K-Y-F-Q-G-K-P-V-V-E-S-I-Q-R-V-S-R-P-G-L-R-I-Y-K-R-K-D-E-L-P-K-V-M-G-G-L-G-V-A-V-V-S-T-S-K-G-V-M-T-D-R-A-A-R-Q-A-G-L-G-G-E-I-I-C-Y-V-A


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-S-I-P-A-G-V-E-V-K-L-D-G-Q-L-L-T-V-K-G-K-N-G-E-L-S-R-T-I-H-N-A-V-E-V-K-Q-D-N-N-E-L-T-F-S-P-R-E-G-I-V-G-A-D-A-Q-A-G-T-A-R-A-L-V-N-A-M-V-I-G-V-T-E-G-F-T-K-K-L-Q-L-V-G-V-G-Y-R-A-Q-I-K-G-N-A-V-A-L-S-L-G-F-S-H-P-V-E-H-A-L-P-A-G-I-T-A-E-C-P-S-Q-T-E-I-V-L-K-G-A-D-K-Q-L-I-G-Q-V-A-A-D-I-R-A-Y-R-R-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-V-V-R-I-K-E-A-K-K-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-S-A-R-I-R-R-A-A-R-A-R-H-M-M-R-E-Q-G-V-T-R-L-V-I-H-R-T-P-R-H-I-Y-A-Q-V-I-A-P-N-G-S-E-V-L-A-A-A-S-T-V-E-K-V-I-S-E-Q-V-K-Y-T-G-N-K-D-A-A-A-V-V-G-K-V-V-A-E-R-A-L-A-K-G-V-K-D-V-A-F-D-R-S-G-F-K-Y-H-G-R-V-Q-T-L-A-D-A-A-R-E-A-G-L-Q-F


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-N-I-E-K-Q-A-G-E-L-Q-E-K-L-I-A-V-N-R-V-S-K-T-V-K-G-G-R-I-M-S-F-T-A-L-T-V-V-G-D-G-N-G-R-V-G-F-G-Y-G-K-A-R-E-V-P-A-A-I-Q-K-A-M-E-K-A-R-R-N-M-I-N-V-A-L-N-E-G-T-L-Q-H-P-I-K-G-A-H-T-G-S-R-V-F-M-Q-P-A-S-E-G-T-G-I-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-R-N-V-L-S-K-A-Y-G-S-T-N-P-I-N-V-V-R-A-T-I-D-A-L-A-N-M-K-S-P-E-M-V-A-A-K-R-G-K-T-V-D-E-I-L-G


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-S-P-A-E-G-A-K-H-S-A-K-R-L-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-K-S-R-T-G-G-G-V-R-R-G-F-E-G-G-Q-M-P-L-Y-R-R-L-P-K-F-G-F-T-S-M-K-A-A-V-T-A-E-V-R-L-N-D-L-A-K-V-E-G-G-V-V-T-L-E-S-L-K-A-A-N-V-I-T-K-D-I-Q-F-V-K-I-I-L-A-G-E-V-K-G-A-V-V-V-R-G-L-R-V-T-K-G-A-K-A-A-I-E-A-A-G-G-S-V-E-E


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-H-K-H-T-V-I-A-L-T-A-I-Y-G-I-G-K-T-R-A-Q-A-I-C-A-A-T-G-I-A-E-D-V-K-I-S-E-L-S-E-E-Q-I-D-K-L-R-D-E-V-G-K-F-T-V-E-G-D-L-R-R-E-V-T-L-N-I-K-R-L-L-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-T-P-V-R-A-R-K-R-V-K-K-Q-V-V-D-G-V-A-H-I-H-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-A-L-A-W-A-T-A-G-G-S-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-V-A-A-E-R-C-A-E-V-V-K-E-F-G-L-K-N-L-E-V-M-V-K-G-P-G-P-G-R-E-S-T-I-R-A-L-N-A-A-G-F-R-I-T-N-I-T-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-S-I-E-P-R-K-I-L-P-D-P-K-F-G-S-E-L-L-A-K-F-I-N-V-L-M-V-D-G-K-K-S-I-A-E-K-I-V-Y-S-A-L-D-T-L-A-Q-R-T-G-K-E-A-L-E-A-F-E-A-A-L-D-N-V-R-P-T-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-V-R-P-V-R-R-N-A-L-G-M-R-W-I-V-D-A-A-R-K-R-G-D-K-S-M-A-L-R-L-A-N-E-L-S-D-A-S-E-N-K-G-A-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W


### FUNCTION Could be part of a sulfur-relay system ### SEQUENCE -M-R-Y-V-L-C-V-K-Q-P-A-Y-G-K-Q-G-G-F-L-A-Y-Q-L-A-K-A-L-L-E-K-G-H-Q-I-T-Q-V-F-F-F-Q-E-G-V-T-H-G-N-A-F-L-Y-P-A-S-D-E-F-N-L-Q-H-A-W-Q-R-L-A-Q-D-Y-H-V-P-L-H-L-C-V-A-A-A-Q-R-R-G-V-V-E-P-L-T-S-S-T-T-Q-Q-N-N-L-A-S-C-F-V-L-A-G-L-G-E-F-M-K-A-S-L-E-A-D-R-V-V-C-L


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-N-I-I-K-Q-L-E-Q-E-Q-L-K-Q-N-L-P-S-F-R-P-G-D-T-L-E-V-K-V-W-V-V-E-G-S-K-R-R-L-Q-A-F-E-G-V-V-I-A-I-R-N-R-G-L-H-S-A-F-T-L-R-K-V-S-N-G-V-G-V-E-R-V-F-Q-T-H-S-P-I-V-D-S-I-T-V-K-R-K-G-A-V-R-Q-A-K-L-Y-Y-L-R-E-R-S-G-K-S-A-R-I-K-E-R-L-G-D


### FUNCTION This regulatory protein, when combined with SAM  represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-A-N-W-D-G-K-Y-I-S-P-Y-A-E-H-G-K-K-S-E-Q-V-K-K-I-T-V-S-I-P-I-K-V-L-E-I-L-T-N-E-R-T-R-R-Q-I-R-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-F-T-G-Q-P-L-P-T-D-E-D-L-L-K-E-R-H-D-E-I-P-E-Q-A-K-Q-V-M-R-E-L-G-I-D-P-E-K-W-E-Y


### FUNCTION Required for resistance to DNA-damaging agents ### SEQUENCE -M-Y-K-H-V-L-V-A-V-D-L-S-D-E-S-Q-F-L-L-E-K-A-A-G-V-A-R-R-N-E-A-K-L-S-I-I-H-V-D-V-N-F-S-D-L-Y-T-G-L-I-D-V-N-M-A-S-M-Q-D-R-I-S-T-E-T-Q-Q-S-L-V-Q-L-A-E-N-S-S-Y-P-V-A-E-K-L-S-G-S-G-D-L-G-Q-V-L-A-D-A-I-E-K-Y-D-V-D-L-L-V-T-G-H-H-Q-D-F-W-S-K-L-M-S-S-T-R-Q-V-M-N-N-I-A-V-D-M-L-V-V-P-L-R-D-E


### FUNCTION Regulates the transcription of the pyrimidine nucleotide  operon in response to exogenous pyrimidines ### SEQUENCE -M-E-K-I-I-I-D-E-N-Q-F-L-R-T-I-S-R-I-S-H-E-I-I-E-K-H-Q-R-L-D-N-I-V-I-V-G-I-K-R-R-G-A-E-I-A-E-L-I-K-K-K-I-A-D-L-A-N-V-E-L-P-S-I-D-L-D-I-T-F-Y-R-D-D-L-E-Y-A-E-P-D-S-K-S-P-T-Y-S-G-A-S-S-F-I-S-I-H-N-K-E-V-I-L-V-D-D-V-L-Y-T-G-R-T-I-R-A-A-L-D-A-L-V-D-F-G-R-A-A-K-I-E-L-V-I-F-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-V-P-T-S-R-S-E-E-V-Q-V-R-T-L-K-F-D-N-C-Y-E-V-A-L-L-S-P-T-K


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-P-G-M-I-E-R-Y-T-G-S-V-K-E-A-G-G-Q-V-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-N-K-L-H-K-A-H-Y-V-L-M-N-V-E-A-P-Q-E-V-I-D-E-L-E-T-T-F-R-Y-N-D-A-V-L-R-N-V-I-I-R-T-K-H-A-V-T-E-A-S-P-M-V-K-A-K-D-D-R-K-A-L-A-E-V-E-N-N-D-F-E-D-A-E-E


### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-L-K-S-N-L-N-I-D-N-R-F-S-L-I-G-I-V-A-S-Q-P-K-R-H-Q-S-P-N-G-I-Y-H-C-Q-F-V-L-E-H-R-S-I-Q-E-E-A-G-L-S-R-Q-A-W-C-K-M-P-V-Q-M-S-G-N-Q-F-R-E-K-T-Q-S-I-T-V-G-S-Q-L-L-V-V-G-F-I-S-S-H-K-T-A-N-G-L-S-Q-L-V-L-H-A-E-Q-I-E-F-I-D


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-L-L-D-K-V-V-H-L-G-N-I-G-D-Q-V-N-V-K-S-G-F-A-R-N-F-L-I-P-Q-G-K-A-V-M-A-T-K-A-N-I-E-Y-F-E-A-R-R-A-E-L-E-A-K-A-A-E-V-L-A-A-A-Q-A-R-A-A-K-L-A-E-L-G-S-V-T-I-A-S-K-A-G-D-E-G-R-L-F-G-S-I-T-T-R-D-V-A-D-A-V-T-A-A-G-V-E-V-A-K-S-E-V-R-L-S-T-G-P-I-R-T-L-G-D-H-E-V-K-F-Q-L-H-G-E-V-F-A-T-I-N-V-I-V-V-A-E


### FUNCTION Globally modulates RNA abundance by binding to RNase E  and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome Modulates RNA-binding and helicase activities of the degradosome ### SEQUENCE -M-Y-I-D-T-S-E-L-C-D-I-Y-L-D-Q-V-D-V-V-E-P-I-F-S-S-F-G-G-V-N-R-F-Y-G-K-V-T-T-V-K-C-F-E-N-N-G-L-I-T-D-I-L-E-E-N-G-E-G-R-V-L-L-I-D-G-G-G-A-V-R-R-A-L-V-D-A-E-L-A-Q-L-A-V-D-N-G-W-E-G-I-I-V-Y-G-A-V-R-Q-I-Q-Q-L-E-E-M-D-I-G-I-H-A-L-A-P-I-P-V-G-A-D-K-Q-N-I-G-E-I-D-V-P-V-N-F-G-G-V-T-F-F-P-E-D-Y-V-Y-A-D-L-T-G-I-I-L-S-Q-E-P-L-E-L-D-E-F-N-D-A


### FUNCTION Required for nucleoid occlusion  are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions ### SEQUENCE -M-Q-K-P-V-K-R-S-L-K-E-R-R-Q-Q-V-L-T-V-L-T-H-M-L-H-S-E-R-G-M-E-R-M-T-T-A-R-I-A-A-E-V-G-V-S-E-A-A-L-Y-R-Y-Y-P-S-K-T-K-M-F-E-A-L-I-D-N-L-E-A-H-L-F-T-R-I-T-Q-S-V-K-N-E-T-H-T-A-A-R-V-H-N-I-M-Q-M-V-L-D-F-A-R-K-N-P-G-L-T-R-I-L-T-G-H-A-L-M-F-E-E-P-Q-L-Q-A-R-V-A-Q-F-F-D-R-L-E-L-Q-F-I-N-I-L-Q-M-R-K-L-R-E-G-K-G-F-D-Y-E-E-R-V-I-A-A-H-L-V-N-L-C-E-G-H-F-M-R-Y-V-R-S-N-F-R-H-S-T-Q-Q-S-F-E-Q-Q-W-R-L-L-E-R-L-F-A


### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-Q-G-I-H-P-N-Y-V-E-V-T-A-T-C-S-C-G-N-V-I-K-T-R-S-T-V-G-K-D-L-N-L-D-V-C-G-N-C-H-P-F-Y-T-G-K-Q-R-V-V-D-T-G-G-R-V-E-R-F-N-K-R-F-S-I-P-S-T-K


### FUNCTION Component of the thioredoxin-thioredoxin reductase system Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-E-V-L-H-S-T-D-A-T-F-T-A-D-V-V-N-S-D-V-P-V-L-L-D-F-W-A-P-W-C-G-P-C-R-M-I-S-P-I-L-D-E-I-A-A-E-F-S-G-K-V-K-V-V-K-I-N-I-D-E-N-Q-A-T-P-A-Q-L-G-V-R-S-I-P-T-L-V-L-F-K-N-G-K-A-V-A-T-Q-V-G-A-L-P-K-N-Q-L-A-N-F-I-N-Q-N-I


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-G-A-V-E-K-I-G-N-R-F-D-L-I-L-T-A-A-R-R-A-R-Q-L-Q-L-H-I-R-E-P-L-V-P-E-D-N-D-K-P-T-V-I-A-L-R-E-I-E-K-G-L-I-N-N-E-I-M-N-A-Q-E-R-Y-D-A-L-E-K-E-N-S-E-L-H-A-V-S-L-L-S-N-Q


### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate  for the ubiquinone pathway ### SEQUENCE -M-S-N-Y-S-Q-L-L-Q-N-A-T-W-Q-P-S-T-D-M-Q-L-P-L-S-I-S-S-W-L-E-L-S-T-S-L-T-T-Q-L-K-Q-A-F-G-E-V-N-V-C-V-L-A-E-S-W-I-T-T-L-N-E-N-E-R-Q-F-F-P-K-Q-A-C-P-C-W-C-R-E-V-I-L-K-S-Q-D-I-P-L-I-F-A-R-T-L-I-P-A-S-L-L-T-Q-H-S-E-L-Q-Q-L-G-N-R-A-L-G-E-W-L-F-M-Q-S-D-R-I-R-Q-K-L-E-L-T-H-D-K-N-T-A-L-Y-A-R-R-A-L-M-S-I-G-A-E-N-M-M-V-A-E-L-F-L-T-P-Q-I-F-T-R-V-V-K


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-Y-L-N-A-L-R-R-E-R-I-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-N-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-S-V-S-H-H-N-N-S-N-N-S-N-Q-Q-N-Y-Q-Q-E-Q-Q-T-D-S-N-V-E-K-A-E


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-R-L-V-Q-K-C-H-A-V-A-A-K-D-V-E-N-A-V-K-E-I-L-D-Q-M-S-F-A-L-E-S-G-K-R-I-E-V-R-G-F-G-S-F-S-L-H-Y-R-Q-P-R-L-G-R-N-P-K-T-G-E-Q-V-K-L-D-A-K-S-V-P-H-F-K-A-G-K-E-L-R-E-R-V-D-I-Y-A


### FUNCTION Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters ### SEQUENCE -M-E-T-L-D-K-I-K-K-Q-I-S-E-N-P-I-L-I-Y-M-K-G-S-P-K-F-P-S-C-G-F-S-A-R-A-V-E-A-L-M-H-C-K-V-P-F-G-Y-V-D-I-L-Q-H-P-D-I-R-A-E-L-P-A-Y-A-N-W-P-T-F-P-Q-L-W-V-D-G-E-L-V-G-G-C-D-I-I-L-E-M-F-Q-Q-G-E-L-Q-T-L-L-A-D-V-A-A-K-Y-P-Q-E


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-T-L-E-Q-K-L-Q-E-L-L-Q-S-S-V-E-D-L-G-C-E-L-W-G-I-E-C-Q-R-A-G-R-Y-L-T-V-R-L-Y-I-D-K-E-G-G-V-T-V-E-D-C-A-D-V-S-R-Q-V-S-A-I-L-D-V-E-D-P-I-A-D-K-Y-N-L-E-V-S-S-P-G-L-D-R-A-L-F-T-L-D-Q-Y-Q-R-Y-I-G-Q-E-I-V-V-H-L-R-I-P-V-L-D-R-R-K-W-Q-G-K-L-E-K-I-E-N-D-M-L-T-L-I-V-D-G-Q-E-Q-I-L-V-F-G-N-I-Q-K-A-N-I-I-P-K-F


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-S-T-E-E-T-K-V-I-D-S-R-L-V-S-E-G-Y-Q-V-R-R-R-R-E-C-G-N-C-H-E-R-F-T-T-F-E-T-A-E-L-I-I-P-K-V-I-K-N-D-G-T-R-E-P-F-N-E-E-K-L-R-R-G-I-Q-H-A-L-E-K-R-P-V-S-E-N-D-V-E-K-A-I-S-Y-I-I-H-R-L-R-S-T-G-E-R-E-V-P-S-K-L-V-G-T-L-V-M-E-E-L-K-K-L-D-K-V-A-Y-I-R-F-A-S-V-Y-L-S-F-D-D-I-N-Q-F-S-K-E-I-E-K-L-R-D


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-F-K-F-N-A-E-V-R-Q-S-Q-G-K-G-A-S-R-R-L-R-H-N-G-Q-I-P-A-I-V-Y-G-G-S-E-A-P-V-S-I-V-L-N-H-D-D-L-N-N-A-Q-V-H-D-A-F-Y-T-D-V-I-T-L-V-I-E-G-K-E-V-A-V-K-A-Q-A-M-Q-R-H-P-F-K-P-K-L-V-H-I-D-F-K-R-V


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-L-T-K-V-E-L-A-D-N-L-I-E-K-L-H-L-N-K-R-D-A-K-E-L-V-E-N-F-F-E-E-I-R-V-A-L-E-T-G-E-D-V-K-L-S-G-F-G-N-F-E-L-R-D-K-S-S-R-P-G-R-N-P-K-T-G-E-S-V-P-V-S-A-R-R-V-V-A-F-K-P-G-Q-K-L-R-A-R-V-E-K-T-K-P-K-S


### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-T-Q-Q-A-I-F-A-G-G-C-F-W-C-V-E-A-V-F-N-Q-I-K-G-V-E-K-A-T-S-G-Y-I-N-G-T-T-E-N-P-T-Y-K-E-V-C-T-G-E-T-G-H-A-E-A-V-K-V-E-F-D-A-T-V-I-S-Y-E-K-L-L-D-I-F-F-S-I-H-N-P-T-Q-L-N-H-Q-G-E-D-V-G-T-Q-Y-R-T-G-I-Y-Y-L-N-D-E-Q-E-Q-L-A-N-K-K-I-A-E-L-Q-P-H-F-A-E-K-I-V-T-E-V-L-P-A-Q-T-F-Y-P-A-E-D-Y-H-Q-G-Y-L-L-Q-N-P-Q-N-S-Y-C-N-L-V-A-T-P-K-F-L-K-A-K-V-K-F-E-E-I-W-K


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-A-R-H-K-K-V-L-K-A-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-A-R-Q-N-G-L-S-Y-S-K-F-I-N-G-L-K-K-A-S-V-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-V-A-F-T-A-L-V-E-K-A-K-S-A-L


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-T-V-K-K-A-P-V-A-N-R-P-N-R-I-N-D-E-I-R-V-K-E-V-R-L-I-D-Q-D-G-E-Q-A-G-I-V-S-I-Q-Q-A-L-E-M-A-E-Q-A-E-L-D-L-V-E-I-S-P-N-A-E-P-P-V-C-R-I-M-N-Y-G-K-F-L-Y-E-K-G-K-A-A-K-E-Q-K-K-K-Q-K-V-V-Q-V-K-E-I-K-F-R-P-G-T-D-E-G-D-Y-Q-V-K-L-R-S-L-I-R-F-L-E-E-G-D-K-A-K-I-T-V-R-F-R-G-R-E-M-A-H-Q-D-I-G-L-E-V-L-E-R-V-K-N-D-L-A-E-I-S-V-V-E-S-A-P-G-R-L-E-G-R-Q-A-V-M-V-L-A-P-K-K-K


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-K-K-S-T-E-K-T-E-L-D-F-E-N-T-L-Q-Q-L-E-A-I-V-T-R-L-E-S-G-E-L-P-L-E-S-A-L-E-E-F-E-R-G-I-K-L-A-H-L-G-Q-E-R-L-Q-Q-A-E-Q-R-I-Q-I-L-L-Q-K-S-D-S-A-K-L-S-D-Y-Q-A-E-E


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-V-A-K-P-E-T-V-K-R-D-W-Y-V-V-D-A-T-G-K-T-L-G-R-L-A-T-E-L-A-R-R-L-R-G-K-H-K-A-E-Y-T-P-H-V-D-T-G-D-Y-I-I-V-I-N-A-E-K-V-A-V-T-G-N-K-E-S-D-K-L-Y-H-W-H-T-G-Y-V-G-G-I-K-Q-A-T-F-K-E-M-I-A-R-R-P-E-A-V-I-E-I-A-V-K-G-M-L-P-K-G-P-L-G-R-A-M-Y-R-K-L-K-V-Y-A-G-S-E-H-N-H-A-A-Q-Q-P-Q-V-L-D-I


### FUNCTION Required for spatial organization of the terminus region of the chromosome  during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-K-L-E-N-Q-E-A-H-W-K-W-L-Y-L-I-K-K-H-R-E-G-E-N-I-T-R-Y-E-E-R-S-L-S-E-D-K-V-K-Q-L-L-S-Q-Q-N-Q-P-Q-A-I-E-N-W-I-K-A-H-L-S-P-H-L-M-I-K-L-D-Q-A-I-R-A-R-R-K-R-F-F-N-G-E-K-Q-S-T-K-K-K-S-I-D-L-E-Y-A-V-W-L-R-L-S-R-Y-S-R-K-M-K-M-T-L-S-E-T-I-T-Y-M-I-D-E-R-E-S-K-A-Q-Y-E-H-Q-I-S-A-M-K-A-G-L-K-D-L-L-K


### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-M-T-E-I-S-V-P-L-I-F-T-D-A-A-A-N-K-V-K-A-L-I-S-E-E-E-N-P-N-L-K-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-K-V-N-D-G-D-L-T-I-E-K-S-G-V-H-L-V-I-D-P-M-S-L-Q-Y-L-I-G-G-T-V-D-Y-T-E-G-L-E-G-S-R-F-V-V-N-N-P-N-A-S-T-T-C-G-C-G-S-S-F-S-I


### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-Q-S-T-A-R-T-L-S-V-N-K-H-I-A-L-V-A-H-D-H-C-K-Q-D-L-I-N-W-C-K-T-H-R-T-L-L-A-Q-H-T-L-Y-A-T-G-T-T-G-N-L-I-Q-K-E-A-N-L-P-I-K-S-L-L-S-G-P-M-G-G-D-Q-Q-L-G-G-L-I-A-E-K-Q-I-D-V-L-I-F-F-W-D-P-M-N-A-V-P-H-D-P-D-V-K-A-L-M-R-I-A-T-V-W-N-I-P-V-A-M-N-M-A-T-A-D-F-L-I-T-S-P-S-F-A-Q-E-T-Q-V-R-I-P-D-Y-D-G-Y-L-K-E-R-L-K


### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-T-E-Y-I-L-L-I-I-S-T-A-L-I-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-I-E-T-A-I-G-M-S-L-A-T-M-F-V-L-T-V-A-S-I-S-A-Y-L-I-D-T-Y-I-L-T-P-L-S-A-T-F-L-R-T-L-V-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-V-I-N-K-T-S-P-T-L-Y-R-L-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-I-N-Q-A-H-T-L-T-Q-S-V-I-Y-G-F-G-A-S-L-G-F-G-L-V-L-V-L-F-A-A-L-R-E-R-L-A-A-A-D-V-P-H-V-F-K-G-A-S-I-A-L-I-T-A-G-L-M-S-L-A-F-M-G-F-T-G-L-V-R


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-S-E-G-Q-V-V-R-L-E-K-L-E-V-A-T-G-E-T-V-E-F-D-S-V-L-M-I-V-N-G-E-D-V-K-I-G-A-P-V-V-A-G-G-K-V-V-A-E-V-V-A-H-G-R-G-D-K-V-K-I-V-K-F-R-R-R-K-H-S-R-K-Q-Q-G-H-R-Q-W-F-T-E-V-K-I-T-G-I-Q-A


### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-Y-L-S-R-N-L-E-Q-W-H-A-F-V-E-M-L-R-T-A-F-A-Q-G-K-E-Q-E-I-L-T-L-L-L-T-P-D-E-R-D-S-V-G-L-R-L-Q-I-V-A-Q-L-L-D-K-S-V-P-Q-R-E-I-Q-Q-N-L-N-T-S-A-A-T-I-T-R-G-S-N-M-I-K-T-M-P-P-E-F-M-A-W-V-K-E-Q-L-D-E-Q-A-K-K-D


### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-P-F-N-I-F-D-L-P-V-D-F-H-V-D-Q-A-T-L-S-A-R-Y-L-A-L-Q-K-S-L-H-P-D-N-F-T-T-H-S-A-Q-E-Q-R-L-A-M-Q-R-S-A-E-V-N-D-A-L-Q-I-L-K-D-P-I-L-R-A-E-T-I-I-A-I-Y-T-G-E-Q-Q-N-I-E-E-N-S-T-R-D-M-A-F-L-M-Q-Q-M-Q-W-R-E-Q-L-E-N-I-E-A-Q-Q-D-S-D-Q-L-V-A-F-S-A-D-I-E-Q-T-Q-Q-A-L-L-S-E-L-A-D-A-L-S-S-Q-Q-W-Q-Q-A-K-V-I-N-D-K-L-R-F-I-K-K-L-L-L-E-V-E-R-V-E-E-K-L-L-D-F


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-S-T-E-K-K-A-A-I-V-A-E-F-G-R-D-A-K-D-T-G-S-S-E-V-Q-I-A-L-L-T-A-Q-I-N-H-L-Q-S-H-F-A-T-H-K-K-D-H-H-G-R-R-G-L-L-R-M-V-S-R-R-R-K-L-L-D-Y-L-K-R-T-N-L-E-L-Y-T-S-T-I-A-R-L-G-L-R-R


### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-Y-Q-T-L-L-L-G-Y-A-I-I-A-I-V-I-V-F-L-I-L-I-Q-Q-G-K-G-A-D-A-G-A-S-F-G-G-G-A-S-G-T-I-F-G-S-V-G-S-G-N-F-L-S-K-M-T-A-L-L-A-T-A-F-F-V-M-S-I-V-I-G-N-V-N-S-H-R-N-N-V-K-Q-G-K-F-D-D-L-S-A-T-A-E-Q-I-Q-Q-Q-Q-K-I-D-A-P-A-V-E-T-K-N-S-D-I-P-Q


### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-T-A-T-T-S-K-R-K-K-Y-V-R-E-M-K-P-T-W-W-K-K-L-D-F-Y-K-L-Y-I-A-R-E-A-T-A-I-P-T-L-W-F-C-L-V-L-L-Y-G-V-I-S-L-G-S-L-D-S-F-G-N-F-I-S-F-L-K-N-P-I-V-I-I-L-N-I-I-T-L-G-A-M-L-L-N-T-V-T-Y-Y-V-M-T-P-K-V-L-N-I-I-V-K-N-E-R-I-N-P-N-I-I-T-M-A-L-W-A-V-T-A-F-I-S-L-V-I-L-V-F-M-Y-V


### FUNCTION Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones ### SEQUENCE -M-K-D-T-P-K-R-S-N-E-P-V-V-W-L-L-F-G-A-G-T-T-V-S-A-M-F-Y-P-V-L-V-L-I-L-G-F-L-L-P-F-G-L-I-D-P-K-N-I-I-E-L-I-G-F-L-H-S-P-L-G-K-L-L-L-L-V-L-L-I-F-P-M-W-G-A-M-H-R-I-H-H-G-M-H-D-F-K-I-H-I-P-A-S-G-V-I-F-Y-G-L-S-V-L-Y-T-V-L-V-C-F-A-V-F-S-L


### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-T-D-D-I-F-S-V-P-C-P-I-C-Q-K-Q-V-E-W-S-D-K-S-P-F-R-P-F-C-C-K-R-C-Q-L-I-D-L-G-E-W-A-A-E-E-K-A-I-P-C-E-S-A-D-F-A-M-N-D-E-Q-E-D-W-R-A-H


### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-K-G-I-Q-I-T-Q-A-A-N-D-N-L-L-N-S-F-W-L-L-D-S-E-K-G-E-A-R-C-L-C-A-K-G-D-F-V-E-D-Q-I-V-A-V-S-E-L-G-Q-I-E-Y-R-E-L-P-V-D-I-A-P-T-V-K-V-E-G-G-Q-H-L-N-V-N-V-L-R-R-E-T-L-E-D-A-V-N-N-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-T-R-T-F-T-Q-S-L


### FUNCTION Binds to type I regulatory subunits of protein kinase A  and may anchor/target them to the plasma membrane ### SEQUENCE -M-G-C-M-K-S-K-E-T-F-P-F-P-T-T-L-D-I-D-K-L-H-E-S-E-E-A-F-I-P-D-D-S-S-Q-Y-R-T-P-S-P-G-E-Q-Q-Q-V-Q-E-V-K-K-L-P-E-P-G-A-V-I-G-A-L-I-L-E-F-A-D-R-L-A-S-E-I-V-E-D-A-L-Q-Q-W-A-C-E-N-I-Q-Y-Y-N-I-P-Y-I-E-S-E-G-S-D-T-T-I-N


### FUNCTION Required for the assembly of the mitochondrial NADHubiquinone oxidoreductase complex  Involved in the assembly of the distal region of complex I ### SEQUENCE -M-G-S-S-F-S-G-S-T-E-F-S-A-P-A-P-P-T-V-S-T-A-V-P-A-N-P-P-A-K-S-A-V-P-A-S-P-A-R-D-P-E-L-K-T-C-W-S-C-R-V-L-S-G-S-T-L-F-G-A-G-T-Y-V-Y-L-V-A-R-R-P-L-K-Q-G-I-P-P-G-P-G-T-V-L-Q-M-V-I-G-I-S-I-A-C-W-G-V-V-V-L-V-D-P-K-G-K-S-H-P-V-I


### FUNCTION May modulate activity of cullin-RING E3 ubiquitin ligase  complexes Down-regulates activation of NF-kappa-B ### SEQUENCE -M-R-F-R-F-C-G-D-L-D-C-P-D-W-V-L-A-E-I-S-T-L-A-K-I-S-S-V-K-L-R-L-L-C-S-Q-V-L-K-E-L-L-G-Q-G-I-D-Y-E-K-I-L-K-L-T-A-D-A-K-F-E-S-G-D-V-K-A-T-V-A-V-L-S-F-I-L-S-S-A-A-K-H-S-V-D-S-D-S-L-S-S-E-L-Q-Q-L-G-L-P-K-E-H-A-T-S-L-C-R-C-Y-E-E-K-Q-S-P-L-Q-E-H-L-R-A-C-S-L-R-V-N-R-L-A-S-V-G-W-R-V-D-Y-T-L-S-S-S-L-L-H-S-V-E-E-P-M-V-H-L-Q-L-Q-V-V-P-A-P-G-T-Q-A-Q-P-V-S-M-S-L-S-A-D-K-F-Q-V-L-L-A-E-L-K-Q-A-Q-T-M-M-T-A-L-G


### FUNCTION Substrate-recognition component of the SCF -type E3 ubiquitin ligase complex ### SEQUENCE -M-A-S-W-L-P-E-T-L-F-E-I-V-G-Q-G-P-A-P-S-K-D-Y-Y-Q-L-L-I-T-R-T-Q-I-I-F-R-W-W-K-I-S-L-R-S-E-Y-R-S-A-K-P-G-E-T-K-E-S-H-E-D-F-L-D-N-S-H-L-Q-V-Q-V-A-V-V-F-G-T-K-I-L-D-Y-V-F-N-L-C-E-G-K-F-D-Y-L-E-R-L-S-D-R-L-L-L-K-I-I-C-Y-L-D-L-E-D-I-A-S-L-S-Q-T-S-S-K-F-E-K-L-C-K-S-D-L-L-W-E-Q-I-V-Q-S-T-C-D-T-I-T-P-D-M-R-A-L-A-K-N-M-G-W-R-Q-M-F-L-T-N-N-I-Q-L-Q-R-Q-T-R-K-K-K-Q-R-Q-E-N-Q-A-E-K-L-A


### FUNCTION May promote cell proliferation and inhibition of apoptosis of preadipocytes ### SEQUENCE -M-T-A-A-T-R-Q-E-V-L-C-L-Y-R-S-I-F-R-L-A-R-K-W-Q-A-A-S-G-Q-M-E-D-T-I-E-E-K-Q-Y-I-L-K-E-A-R-T-L-F-Q-K-N-K-N-L-T-D-P-E-L-I-K-Q-C-I-V-E-C-T-A-R-I-E-I-G-L-H-Y-Q-I-P-Y-P-R-P-I-H-L-P-P-M-G-L-T-A-R-R-G-R-G-L-Q-T-Q-E-K-L-R-K-L-S-K-P-V-Y-L-K-S-H-D-E-V-S


### FUNCTION Mitochondrial ribosome-associated protein involved in the first steps of cytochrome c oxidase complex  biogenesis Stimulates the translation of MT-CO1 mRNA and is a constituent of early MT-CO1 assembly intermediates ### SEQUENCE -M-V-A-S-V-P-L-R-N-V-S-H-L-L-S-V-L-R-S-Q-N-V-P-R-Y-L-Q-N-G-V-P-R-D-V-L-L-F-R-H-E-R-G-R-F-F-A-I-L-G-L-F-C-A-G-Q-G-I-F-W-T-S-L-A-V-A-A-L-S-R-P-L-S-R-V-P-A-E-A-P-N-R-S-Y-Q-D-L-R-S-A-L-W-R-Y-G-L-A-V-G-C-G-T-M-G-V-L-V-L-G-A-G-L-L-Y-S-L-R-S-V-R-S-V-M-L-L-A-G-G-Q-Q-V-T-L-T-T-Y-A-P-F-G-L-G-T-C-F-T-V-P-L-N-Q-I-S-C-M-A-H-R-G-E-V-P-A-M-L-P-L-K-V-K-G-R-R-F-Y-F-L-L-D-K-A-G-H-F-P-N-T-Q-L-F-D-N-T-V-G-A-Y-R-S-L


### FUNCTION Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-P-A-T-A-Y-E-R-V-V-Y-K-S-P-S-E-Y-H-Y-M-K-V-C-L-E-F-Q-E-H-G-V-G-L-N-V-A-Q-F-K-Q-L-L-V-S-A-L-R-D-L-F-G-E-V-G-A-A-L-P-V-D-V-L-T-Y-D-E-K-T-L-S-A-I-L-R-I-C-S-S-G-L-V-K-L-W-S-S-L-T-L-F-G-A-Y-K-S-K-K-C-A-F-R-V-I-Q-V-S-P-F-L-L-A-L-S-G-N-S-R-E-Q-V-L-D


### FUNCTION Negatively regulates TSP1 expression at the level of transcription This down-regulation was shown to reduce taxane-induced apoptosis ### SEQUENCE -M-W-N-P-N-A-G-P-N-P-Y-P-P-Q-V-V-C-P-G-G-S-N-P-A-C-P-P-P-L-N-P-A-F-P-P-G-P-C-P-P-G-I-P-Q-G-N-P-A-F-P-P-C-R-P-P-Y-P-V-P-Q-P-G-C-P-G-Y-Q-P-S-G-P-Y-P-P-P-Y-P-P-P-A-P-G-M-C-P-V-N-P-P-A-P-G-M-V-G-P-G-I-V-I-D-K-K-T-R-K-K-M-K-K-A-H-K-K-S-H-K-H-H-K-H-G-K-H-S-S-S-S-S-S-S-S-S-S-D-S-D


### FUNCTION E1-like enzyme which specifically catalyzes the second step in ufmylation Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage Ufmylation is involved in reticulophagy  induced in response to endoplasmic reticulum stress ### SEQUENCE -M-A-D-E-A-T-R-R-V-V-S-E-I-P-V-L-K-T-N-A-G-P-R-D-R-E-L-W-V-Q-R-L-K-E-E-Y-Q-S-L-I-R-Y-V-E-N-N-K-N-S-D-N-D-W-F-R-L-E-S-N-K-E-G-T-R-W-F-G-K-C-W-Y-I-H-D-F-L-K-Y-E-F-D-I-E-F-E-I-P-I-T-Y-P-T-T-A-P-E-I-A-V-P-E-L-D-G-K-T-A-K-M-Y-R-G-G-K-I-C-L-T-D-H-F-K-P-L-W-A-R-N-V-P-K-F-G-L-A-H-L-M-A-L-G-L-G-P-W-L-A-V-E-V-P-D-L-I-Q-K-G-V-I-Q-H-K-E-K-C-S-Q


### FUNCTION Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains ### SEQUENCE -M-S-Q-A-P-E-A-R-P-S-P-P-S-V-Y-H-E-R-Q-R-L-E-L-C-A-V-H-A-L-N-N-V-L-Q-E-Q-L-F-S-Q-E-A-A-D-E-I-C-K-R-L-A-P-D-S-R-L-N-P-H-R-S-L-L-G-T-G-N-Y-D-V-N-V-I-M-A-A-L-Q-G-L-G-L-A-A-V-W-W-D-R-R-R-P-L-S-Q-L-A-L-P-Q-V-L-G-L-I-L-N-L-P-S-P-V-S-L-G-L-L-S-L-P-L-R-R-R-H-W-V-A-L-R-Q-V-D-G-I-Y-Y-N-L-D-S-K-L-R-A-P-E-A-L-G-D-E-D-G-V-R-T-F-L-A-A-A-L-A-Q-G-L-C-E-V-L-L-V-V-T-K-E-V-E-E-A-G-C-W-L-N-T-S


### FUNCTION Probable regulator of exocrine pancreas development ### SEQUENCE -M-A-A-I-P-S-S-G-S-L-V-A-T-H-D-Y-Y-R-R-R-L-G-S-S-S-S-S-S-S-G-G-S-A-E-Y-P-G-D-A-V-L-Q-S-P-G-L-P-K-A-D-P-G-H-W-W-A-S-F-F-F-G-K-S-T-L-P-F-M-T-T-V-L-E-S-P-E-R-S-A-E-S-P-Q-V-S-R-S-P-M-T-C-G-L-T-P-E-T-M-K-Q-Q-P-V-I-H-S-G-Q-T-N-P-R-D-L-S


### FUNCTION May function as a negative regulator of endoplasmic reticulum-stress induced autophagy ### SEQUENCE -M-A-P-K-G-K-V-G-T-R-G-K-K-Q-I-F-E-E-N-K-E-T-L-K-F-Y-L-R-I-I-L-G-A-N-A-I-Y-C-L-V-T-L-V-F-F-Y-S-S-A-S-F-W-A-W-M-A-L-G-F-S-L-A-V-Y-G-A-S-Y-H-S-M-S-S-M-A-R-A-S-F-S-E-D-G-S-L-M-D-G-G-M-D-L-N-M-E-Q-G-M-A-E-H-L-K-D-V-I-L-L-T-A-I-V-Q-V-L-S-C-F-S-L-Y-I-W-S-F-W-L-L-A-P-G-R-A-L-Y-L-L-W-V-N-V-L-G-P-W-F-T-A-D-S-G-A-P-A-P-E-L-N-E-K-R-Q-R-R-Q-E-R-R-Q-M-K-R-L


### FUNCTION As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor ### SEQUENCE -M-A-T-G-T-P-D-S-Q-A-R-F-G-Q-S-V-K-G-L-L-T-E-K-V-N-T-C-G-T-D-V-I-A-L-T-K-Q-V-L-K-G-S-R-S-S-E-L-L-G-Q-A-A-R-N-M-V-L-Q-E-D-A-I-L-H-S-E-D-S-L-R-K-M-A-I-I-T-T-H-L-Q-Y-Q-Q-E-A-I-Q-K-N-V-E-Q-S-P-D-L-Q-D-Q-L-S-H-L-L-K


### FUNCTION May modulate the activity of casein kinase-1 Inhibits CSNK1D autophosphorylation ### SEQUENCE -M-D-P-N-P-R-A-A-L-E-R-Q-Q-L-R-L-R-E-R-Q-K-F-F-E-D-I-L-Q-P-E-T-E-F-V-F-P-L-S-H-L-H-L-E-S-Q-R-P-P-I-G-S-I-S-S-M-E-V-N-V-D-T-L-E-Q-V-E-F-I-D-L-A-D-Q-D-G-A-D-V-F-L-P-C-E-E-S-S-P-A-P-Q-M-S-G-V-D-D-H-P-E-E-L-S-L-L-V-P-T-S-D-R-T-T-S-R-T-S-S-L-S-S-D-S-S-N-L-R-S-P-N-P-S-D-G-G-G-D-T-P-L-A-Q-S-D-E-E-D-G-D-D-G-G-A-E-P-G-P-C-S


### FUNCTION Client-loading PAQosome/R2TP complex cofactor that selects NOP58 to promote box C/D small nucleolar ribonucleoprotein  assembly Acts as a bridge between NOP58 and the R2TP complex via RUVBL1RUVBL2 ### SEQUENCE -M-E-F-Q-G-E-R-G-T-G-P-G-V-S-S-S-S-V-A-C-S-Q-V-T-V-S-R-E-L-L-T-A-G-S-E-G-S-G-G-I-W-D-Q-L-L-I-S-S-K-P-H-P-R-K-T-S-T-L-Q-T-V-R-M-Q-R-S-P-L-L-D-Q-V-Q-A-F-L-P-Q-M-A-Q-A-N-E-K-L-R-R-E-M-A-A-A-P-A-G-H-F-N-I-E-N-I-D-E-T-S-G-N-I-I-Q-M-D-V-A-L-F-E-M-S-R-S-D-S-K-E-E-D-S-P-E-E-S-S-R-D-S-S-G-D-S-S-E-S-E-E-D-V-C-V-P-S-E-V-T-I-E-N-I-K-L-P-N-A-E-G-G-K-G-K-I-E-I-L-D-S-P-A-S-K-K-K-K-Q


### FUNCTION Probably involved in translation ### SEQUENCE -M-S-T-I-Q-N-L-Q-S-F-D-P-F-A-D-A-T-K-G-D-D-L-L-P-A-G-T-E-D-Y-I-H-I-R-I-Q-Q-R-N-G-R-K-T-L-T-T-V-Q-G-I-A-D-D-Y-D-K-K-K-L-V-K-A-F-K-K-K-F-A-C-N-G-T-V-I-E-H-P-E-Y-G-E-V-I-Q-L-Q-G-D-Q-R-K-N-I-C-Q-F-L-L-E-V-G-I-V-K-E-E-Q-L-K-V-H-G-F


### FUNCTION Regulates HCFC1 activity by modulating its subcellular localization Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus ### SEQUENCE -M-I-L-Q-Q-P-L-E-R-G-P-P-S-R-D-P-R-A-T-T-G-V-T-R-G-L-N-A-S-L-S-P-R-E-P-L-H-K-Q-F-L-S-E-E-N-M-A-T-H-F-S-R-L-S-L-H-N-D-H-P-Y-C-S-P-P-V-T-F-P-E-A-L-P-P-L-R-S-P-C-P-E-L-L-L-W-R-Y-P-G-S-L-I-P-E-A-L-R-L-L-R-L-G-D-T-P-S-P-Y-Y-P-A-S-P-A-G-D-I-V-E-L


### FUNCTION May modulate activity of cullin-RING E3 ubiquitin ligase  complexes May down-regulate activation of NF-kappa-B ### SEQUENCE -M-E-P-E-E-G-T-P-L-W-R-L-Q-K-L-P-P-E-Q-G-A-G-L-L-H-K-I-I-D-G-F-C-G-R-A-Y-P-A-H-Q-D-Y-H-S-V-W-N-S-A-E-W-K-H-V-L-E-D-V-T-T-F-F-K-A-V-V-G-K-N-F-S-E-E-E-T-L-Q-Q-L-N-Q-L-N-S-C-H-Q-E-A-V-L-K-C-L-K-S-R-R-N-E-I-K-Q-A-L-L-G-E-I-V-D-I-S-C-A-Q-L-Q-D-F-D-W-Q-L-K-L-A-L-S-S-D-K-I-A-T-L-Q-M-P-L-L-N-L-H-L-D-V-K-E-D-D-K-V-K-P-Y-T-V-E-M-S-K-E-E-L-Q-S-L-I-S-S-L-E-A-A-N-K-V-V-L-Q-L-K


### FUNCTION May be involved in transcriptional regulation ### SEQUENCE -M-Q-K-S-C-D-E-N-E-G-T-P-Q-N-T-P-K-A-D-E-G-H-P-S-E-D-P-P-Q-Q-A-G-E-T-L-Q-A-S-G-E-N-V-R-E-E-T-E-G-S-H-R-G-E-P-A-E-P-S-P-E-P-K-E-D-T-P-A-R-H-L-N-P-E-E-V-I-R-G-V-D-E-L-E-R-L-R-E-E-I-R-R-V-R-N-K-F-V-L-M-H-W-K-Q-R-H-S-R-S-R-P-Y-P-V-C-F-R-P


### FUNCTION Nicotinic acid adenine dinucleotide phosphate  release ### SEQUENCE -M-A-A-P-P-G-E-Y-F-S-V-G-S-Q-V-S-C-R-T-C-Q-E-Q-R-L-Q-G-E-V-V-A-F-D-Y-Q-S-K-M-L-A-L-K-C-P-S-S-S-G-K-P-N-H-A-D-I-L-L-I-N-L-Q-Y-V-S-E-V-E-I-I-N-D-R-T-E-T-P-P-P-L-A-S-L-N-V-S-K-L-A-S-K-A-R-T-E-K-E-E-K-L-S-Q-A-Y-A-I-S-A-G-V-S-L-E-G-Q-Q-L-F-Q-T-I-H-K-T-I-K-D-C-K-W-Q-E-K-N-I-V-V-M-E-E-V-V-I-T-P-P-Y-Q-V-E-N-C-K-G-K-E-G-S-A-L-S-H-V-R-K-I-V-E-K-H-F-R-D-V-E-S-Q-K-I-L-Q-R-S-Q-A-Q-Q-P-Q-K-E-A-A-L-S-S


### FUNCTION Inhibits phosphatase activity of protein phosphatase 1  complexes ### SEQUENCE -M-P-S-R-T-V-R-Y-A-R-Y-S-P-R-Q-R-R-R-R-M-L-A-D-R-S-V-R-F-P-N-D-V-L-F-L-D-H-I-R-Q-G-D-L-E-Q-V-G-R-F-I-R-A-R-K-V-S-L-D-T-I-H-P-S-G-L-A-A-L-H-E-A-V-L-S-G-N-L-E-C-V-K-L-L-V-K-Y-G-A-D-I-H-Q-R-D-E-T-G-W-T-P-L-H-I-A-C-S-D-G-Y-P-D-I-A-R-Y-L-I-S-L-G-A-D-R-D-A-A-N-D-D-G-D-L-P-S-D-L-I-D-P-D-F-K-D-L-V-E-L-F-K-G-T-S-M-D


### FUNCTION Microtubule inner protein  in cilia axoneme, which is required for motile cilia beating ### SEQUENCE -M-A-V-S-C-S-L-N-H-S-T-Y-L-Q-R-Q-N-L-V-C-Y-L-R-N-P-H-Y-G-S-L-I-Y-A-D-G-H-G-E-V-W-T-D-W-N-D-M-S-K-F-L-Q-Y-G-W-R-C-T-T-N-E-N-S-Y-S-N-R-T-L-V-G-N-W-N-Q-E-R-Y-D-L-K-N-I-V-K-P-K-P-L-P-S-Q-F-G-H-A-F-E-T-T-Y-D-A-N-Y-S-R-K-K-P-Q-S-T-H-R-F-K-R-E-P-H-W-F-P-G-H-Q-P-E-L-D-P-P-H-Y-K-C-T-A-K-S-T-Y-M-T-N-Y-S-E-P-Q-P-T-H-Y-S-C-C-V-Y-D-P-S-V-S-Q-S


### FUNCTION May play a role in cell protection during the inflammatory response In epithelial cells, negatively regulates IL6 production and apoptosis through the regulation of MT2A expression ### SEQUENCE -M-K-F-P-C-L-S-F-R-Q-P-Y-A-G-L-I-L-N-G-V-K-T-L-E-T-R-W-R-P-L-L-S-S-V-Q-K-Y-T-I-A-I-H-I-A-H-K-D-W-E-D-D-E-W-Q-E-V-L-M-E-R-L-G-M-T-W-T-Q-I-Q-T-L-L-Q-A-G-E-K-Y-G-R-G-V-I-A-G-L-I-D-I-G-E-T-F-Q-C-P-E-T-L-T-A-E-E-A-V-E-L-E-T-Q-A-V-L-T-N-L-Q-L-K-Y-L-T-Q-V-S-N-P-R-W-L-L-E-P-I-P-R-K-G-G-K-D-I-F-Q-V-D-I-P-E-H-L-I-P-L-E-K-E


### FUNCTION Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B ### SEQUENCE -M-T-D-Q-T-Y-C-D-R-L-V-Q-D-T-P-F-L-T-G-Q-G-R-L-S-E-Q-Q-V-D-R-I-I-L-Q-L-N-R-Y-Y-P-Q-I-L-T-N-K-E-A-E-K-F-R-N-P-K-A-S-L-R-V-R-L-C-D-L-L-S-H-L-Q-Q-R-G-E-R-H-C-Q-E-F-Y-R-A-L-Y-I-H-A-Q-P-L-H-S-H-L-P-S-R-Y-S-P-Q-N-S-D-C-R-E-L-D-W-G-I-E-S-R-E-L-S-D-R-G-P-M-S-F-L-A-G-L-G-L-A-A-G-L-A-L-L-L-Y-C-C-P-P-D-P-K-V-L-P-G-T-R-R-V-L-A-F-S-P-V-I-I-D-R-H-V-S-R-Y-L-L-A-F-L-A-D-D-L-G-G-L


### FUNCTION May form part of 2 intersubunit bridges in the assembled ribosome Upon binding to MALSU1, intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation ### SEQUENCE -M-A-A-L-T-G-L-W-G-S-F-A-H-V-S-R-A-F-S-Q-R-C-F-S-T-S-G-S-L-S-A-V-Q-K-M-T-R-V-R-V-V-D-N-S-A-L-G-S-T-P-Y-H-R-P-P-R-C-I-H-V-Y-N-K-S-G-V-G-K-V-G-D-Q-I-L-L-A-I-R-G-Q-K-K-K-A-L-I-V-G-H-R-M-P-G-S-R-M-T-P-K-F-D-S-N-N-V-V-L-I-E-D-N-G-N-P-V-G-T-R-I-K-I-P-I-P-T-S-L-R-R-R-E-G-E-Y-S-K-V-L-A-I-A-Q-N-F-V


### FUNCTION May have a role in proliferation and/or differentiation ### SEQUENCE -M-A-D-S-G-G-S-S-P-W-W-K-S-L-T-R-K-K-S-K-E-V-T-V-G-V-Q-P-Q-V-R-P-E-T-G-Q-E-P-S-P-P-H-S-D-R-T-S-S-L-P-E-N-Q-H-S-N-I-L-G-D-P-G-E-S-L-R-S-D-K-L-C-E-E-K-T-G-N-S-R-R-N-L-K-I-S-R-S-G-R-F-K-E-K-R-K-M-R-A-T-L-L-P-E-G-D-K-S-P-E-E-A-D-F-P-D-D-P-Q-E-D-K-Q


### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-C-C-G-C-C-G-G-C-G-S-S-C-C-K-P-V-C-C-C-V-P-V-C-S-C-S-S-C-G-G-C-K-G-G-C-S-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-S-S-C-G-G-C-G-S-C-G-A-A-S-P-S-C-V-S-P-A-A-A-S-P-A-V-Q-A-L-L-L-P-V-Q-L-L-Q-A-L-L-L-P-A-Q-L-L-L-V-Q-L-L-L-S-L-L-L-L-H-D-C-G-S-S-C-C-P-M-S-C-S-L-P-I-Y-C-Q-R-E-I


### FUNCTION Binds medium- and long-chain acyl-CoA esters ### SEQUENCE -M-S-L-Q-A-D-F-D-Q-A-A-Q-D-V-R-K-L-K-S-R-P-E-D-E-E-L-K-E-L-Y-G-L-Y-K-Q-S-V-I-G-D-I-N-I-A-C-P-A-M-L-D-L-K-G-K-A-K-W-E-A-W-N-L-Q-K-G-L-S-K-E-D-A-M-C-A-Y-I-S-K-A-R-E-L-I-E-K-Y-G-I


### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-C-C-G-C-S-G-G-C-G-S-S-C-G-G-C-G-S-N-C-C-K-P-V-C-C-C-K-P-V-C-C-C-V-P-A-C-S-C-S-S-C-G-D-C-K-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-S-S-C-G-G-C-G-S-C-G-G-C-K-G-G-C-G-S-C-G-G-C-G-S-C-G-G-C-G-S-C-G-C-C-Q-S-S-C-C-K-P-C-C-C-Q-S-S-C-C-K-P-C-C-C-Q-S-S-C-C-Q-S-S-C-C-K-P-C-C-C-Q-S-S-C-C-K-P-C-C-C-Q-S-S-C-C-A-P-V-C-C-Q-C-K-I


### FUNCTION Required for ciliogenesis ### SEQUENCE -M-L-Q-T-G-N-Y-S-L-V-L-S-L-Q-F-L-L-L-S-Y-D-L-F-V-N-S-F-S-E-L-L-R-M-A-P-V-I-Q-L-V-L-F-I-I-Q-D-I-A-I-L-F-N-I-I-I-I-F-L-M-F-F-N-T-F-V-F-Q-A-G-L-V-N-L-L-F-H-K-F-K-G-T-I-I-L-T-S-V-Y-L-A-L-S-I-S-L-H-V-W-V-M-N-V-R-W-K-N-S-S-S-F-S-W-T-N-G-L-Q-T-L-F-V-F-Q-R-L-A-A-V-L-Y-C-Y-F-Y-K-R-T-A-V-R-L-G-D-P-R-F-Y-Q-D-S-L-W-L-R-K-E-F-M-Q-V-R-R


### FUNCTION May function as a specific light chain of unconventional myosin-10 ### SEQUENCE -M-A-D-Q-L-T-E-E-Q-I-A-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-S-I-T-T-Q-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-Q-G-M-V-N-E-I-D-K-D-G-N-G-T-V-D-F-P-E-F-L-T-M-M-S-R-K-M-K-D-T-D-S-E-E-E-I-R-E-A-F-R-V-F-D-K-D-G-N-G-F-V-S-A-A-E-L-R-H-V-M-T-K-L-G-E-K-L-S-D-E-E-V-D-E-M-I-Q-A-A-D-T-D-G-D-G-Q-V-N-Y-E-E-F-V-H-M-L-V-S-K


### FUNCTION Exoribonuclease that is part of the telomerase RNA 3' end processing complex and which has the ability to all four unpaired RNA nucleotides from 5' end or 3' end with higher efficiency for purine bases ### SEQUENCE -M-A-A-R-G-R-R-A-E-P-P-G-R-E-A-P-G-P-A-G-S-G-R-S-R-W-A-E-S-G-P-G-T-S-P-E-S-G-D-D-E-V-S-G-S-S-P-V-S-S-G-V-N-L-F-A-N-D-G-S-F-L-E-L-F-K-R-K-M-E-E-E-Q-R-Q-R-Q-E-E-P-P-P-G-P-Q-R-P-D-P-P-A-S-A-A-A-G-P-G-N-P-K-R-K-G-G-P-G-P-T-L-S-F-V-G-K-R-R-G-G-N-K-L-A-L-K-T-G-I-V-A-K-K-Q-K-T-E-D-E-V-L-T-S-K-G-D-A-W-A-K-Y-M-A-E-V-K-K-Y-K-A-H-Q-C-G-D-D-D-K-T-R-P-L-V-K


### FUNCTION May be involved in MAP kinase activation, epithelial sodium channel  down-regulation and cell cycling ### SEQUENCE -M-G-T-P-A-S-V-V-S-E-P-P-L-W-Q-V-S-T-P-Q-T-R-G-R-K-Q-A-S-A-N-I-F-Q-D-A-E-L-V-Q-I-Q-G-L-F-Q-R-S-G-D-Q-L-A-E-E-R-A-Q-I-I-W-E-C-A-G-D-H-R-V-A-E-A-L-R-R-L-R-R-K-R-P-P-K-Q-N-H-C-S-R-L-R-V-P-E-P-G-S-T-A-S-D-P-Q-A-S-T-T-D-T-A-S-S-E-Q-S-G-N-S-R-R-T-S-A-R-A-P-R-N-W-N-K-P-G-P-T-G-Y-L-H-Q-I-R-H


### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-A-C-C-V-A-L-C-C-S-V-P-T-G-P-A-T-T-I-C-S-S-D-K-S-C-R-C-G-V-C-L-P-S-T-C-P-H-T-I-W-Q-L-E-P-T-C-C-D-N-C-P-P-P-C-H-I-P-Q-P-C-V-P-T-C-F-L-L-N-S-C-H-P-T-P-D-L-L-T-V-N-L-T-T-Y-V-Q-P-G-C-E-E-P-C-V-P-R-C-C


### FUNCTION May play a role in lysosome homeostasis ### SEQUENCE -M-V-R-I-L-A-N-G-E-I-V-Q-D-D-D-P-R-V-R-T-T-T-Q-H-R-S-S-S-S-Q-Q-G-F-F-N-R-G-H-G-A-P-P-G-G-P-G-P-R-Q-Q-Q-A-G-A-R-L-G-A-A-Q-S-P-F-S-D-L-N-R-Q-L-V-N-M-G-F-P-Q-W-H-L-G-N-H-V-V-E-P-V-T-S-I-L-L-L-F-L-L-M-M-L-G-V-R-G-L-L-L-V-G-L-V-Y-L-V-S-H-L-S-Q-R


### FUNCTION Acts as a mitochondrial iron-sulfur ### SEQUENCE -M-L-S-A-R-S-A-Q-C-M-V-S-M-A-T-R-S-C-V-S-R-G-S-A-G-S-A-A-A-G-P-V-E-A-A-I-R-A-K-L-E-Q-A-L-S-P-E-V-L-E-L-R-N-E-S-G-G-H-A-V-P-A-G-S-E-T-H-F-R-V-A-V-V-S-S-R-F-E-G-M-S-P-L-Q-R-H-R-L-V-H-E-A-L-S-E-E-L-A-G-P-V-H-A-L-A-I-Q-A-K-T-P-A-Q-W-R-E-N-P-Q-L-D-I-S-P-P-C-L-G-G-S-K-K-T-R-G-T-S


### FUNCTION Functions as a component of numerous distinct DCX  E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex ### SEQUENCE -M-A-D-F-L-K-G-L-P-V-Y-N-K-S-N-F-S-R-F-H-A-D-S-V-C-K-A-S-N-R-R-P-S-V-Y-L-P-T-R-E-Y-P-S-E-Q-I-I-V-T-E-K-T-N-I-L-L-R-Y-L-H-Q-Q-W-D-K-K-N-A-A-K-K-R-D-Q-E-Q-V-E-A-E-G-E-S-S-A-P-P-R-K-V-A-R-T-D-S-P-D-M-P-E-D-T


### FUNCTION Co-chaperone that facilitates HSP-mediated activation of TSSK6 ### SEQUENCE -M-E-Q-H-T-S-N-P-T-K-E-K-A-K-E-E-D-S-V-A-C-F-C-P-A-K-S-S-P-S-Y-I-D-L-P-A-N-F-T-P-A-N-F-L-T-I-Q-T-K-L-S-S-G-A-G-Q-K-P-K-G-C-L-G-V-L-E-C-M-Y-A-N-L-Q-L-Q-T-Q-L-A-Q-R-Q-I-A-I-L-E-N-L-Q-A-S-L-S-Q-P-G-S-G-R-E-S-K-N-C-S-L-P-G-L-C-C-K-L-L-L-N-H-L-P-Q-F-H-K


### FUNCTION May play a role in lipid transport ### SEQUENCE -M-V-D-Q-L-Q-G-T-W-K-S-V-S-C-D-N-F-E-N-Y-M-K-E-L-G-V-G-R-A-S-R-K-L-G-C-L-A-K-P-T-V-T-I-S-T-D-G-D-L-I-T-I-K-T-K-S-I-F-K-N-K-E-I-S-F-K-L-G-E-E-F-E-E-T-T-P-S-G-R-K-S-K-S-T-V-I-L-D-N-D-S-L-V-Q-V-Q-D-W-D-G-K-E-A-T-I-C-R-R-L-V-D-G-K-M-V-V-E-S-A-V-N-N-V-T-C-T-R-T-Y-Q-R-V


### FUNCTION May play a role in bone development ### SEQUENCE -M-N-Q-A-D-K-N-Q-E-I-P-S-Y-L-S-D-E-P-P-E-G-S-M-K-D-H-P-Q-Q-Q-P-G-M-L-S-R-V-T-G-G-I-F-S-V-T-K-G-A-V-G-A-T-I-G-G-V-A-W-I-G-G-K-S-L-E-V-T-K-T-A-V-T-T-V-P-S-M-G-I-G-L-V-K-G-G-V-S-A-V-A-G-G-V-T-A-V-G-S-A-V-V-N-K-V-P-L-S-G-K-K-K-D-K-S-D


### FUNCTION Microtubule inner protein  in cilia axoneme, which is required for motile cilia beating ### SEQUENCE -M-E-E-L-A-K-K-E-R-R-A-M-D-P-G-G-L-K-K-E-G-K-V-E-E-E-A-G-K-E-E-G-R-E-E-E-G-G-E-E-E-E-V-T-S-E-T-L-R-G-K-P-R-P-L-P-I-S-A-L-P-A-F-S-Y-I-P-P-R-H-Q-G-P-K-E-R-S-Y-F-S-R-E-G-Q-T-G-I-V-S-L-Y-D-C-V-F-K-R-R-L-D-Y-N-Q-K-L-H-R-D-D-R-E-H-A-K-N-L-G-L-H-I-N-E-E-E-Q-E-R-T-V-P-V-L-M-S-S-V-Y-G-K-R-I-N-Q-P-I-E-P-L-N-R-D-Y-G-H-V-S-H-V-K-T-D-F-Y-R-K-N-E-I-P-S-I-K-G-P-G-F-G-H-I-N-P-A


### FUNCTION May be involved in induction of apoptosis in CD4 T-cells or hepatocytes ### SEQUENCE -M-A-T-P-W-R-R-A-L-L-M-I-L-A-S-Q-V-V-T-L-V-K-C-L-E-D-D-D-V-P-E-E-W-L-L-L-H-V-V-Q-G-Q-I-G-A-G-N-Y-S-Y-L-R-L-N-H-E-G-K-I-I-L-R-M-Q-S-L-R-G-D-A-D-L-Y-V-S-D-S-T-P-H-P-S-F-D-D-Y-E-L-Q-S-V-T-C-G-Q-D-V-V-S-I-P-A-H-F-Q-R-P-V-G-I-G-I-Y-G-H-P-S-H-H-E-S-D-F-E-M-R-V-Y-Y-D-R-T-V-D-Q-Y-P-F-G-E-A-A-Y-F-T-D-P-T-G-A-S-Q-Q-Q-A-Y-A-P-E-E-A-A-Q-E-E-E-S-V-L-W-T-I-L-I-S-I-L-K-L-V-L-E-I-L-F


### FUNCTION May be involved in transcriptional regulation ### SEQUENCE -M-K-P-C-Q-K-M-E-G-N-L-E-K-E-D-E-P-K-P-E-E-E-P-K-P-E-E-K-P-E-E-G-Q-E-P-E-E-E-E-K-S-E-E-T-F-R-E-R-L-I-R-S-L-Q-D-F-Q-E-D-I-H-N-R-H-L-S-S-D-D-L-F-R-D-V-E-E-L-D-E-I-R-K-V-R-N-K-L-I-V-T-R-W-K-A-N-R-S-H-P-Y-P-Y-L-M


### FUNCTION Antagonist of muscle and neuronal nicotinic acetylcholine receptors  with highest affinity for neuronal alpha-7/CHRNA7 nAChRs ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-M-V-C-M-D-L-G-Y-T-T-I-C-Y-N-H-L-S-R-T-P-E-T-T-E-I-C-P-D-S-W-Y-F-C-Y-K-I-S-L-A-D-G-N-D-V-R-I-K-R-G-C-T-F-T-C-P-E-L-R-P-T-G-K-Y-V-Y-C-C-R-R-D-K-C-N-Q


### FUNCTION Plays an important role in the organization of the cytoskeleton Binds to and sequesters actin monomers ### SEQUENCE -M-C-D-K-P-D-L-S-E-V-E-K-F-D-K-K-K-L-K-K-T-N-T-E-E-K-N-T-L-P-S-K-E-T-I-E-Q-E-K-E-C-V-K-S-S


### FUNCTION Seems to act as a signaling molecule involved in the maintenance of iron homeostasis Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages May also have antimicrobial activity ### SEQUENCE -L-Q-V-L-T-E-E-V-G-S-I-D-S-P-V-G-E-H-Q-Q-P-G-G-E-S-M-R-L-P-E-H-F-R-F-K-R-X-S-H-L-S-L-C-R-W-C-C-N-C-C-H-N-K-G-X-G-F-C-C-K-F


### FUNCTION May regulate transcription ### SEQUENCE -M-L-S-W-L-K-G-H-K-R-Y-C-R-F-K-D-C-T-C-E-K-C-I-L-I-I-E-R-Q-R-V


### FUNCTION Plays an important role in the organization of the cytoskeleton Binds to and sequesters actin monomers ### SEQUENCE -M-S-D-K-P-D-V-K-E-V-E-S-F-D-K-T-T-L-K-K-T-T-T-N-E-K-N-T-L-P-T-K-E-V-I-E-Q-E-K-S-G-G-S-D


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-K-V-E-L-C-S-F-S-G-Y-K-I-Y-P-G-H-G-R-R-Y-A-R-I-D-G-K-V-F-Q-F-L-N-A-K-C-E-S-A-F-L-A-K-R-N-P-R-Q-I-N-W-T-V-L-Y-R-R-K-H-K-K-G-Q-S-E-E-V-T-K-K-R-T-R-R-A-V-K-F-Q-R-A-I-T-G-A-S-L-A-E-I-M-A-K-R-N-Q-K-P-E-V-R-K-A-Q-R-E-Q-A-I-R-A-A-K-E-S-K-K-A-K-Q-A-T-K-K-P-A-A-A-S-A-K-T-S-A-K-T-A-Q-K-P-K-I-A-K-P-M-K-I-S-A-P-R-V-G-G-K-R


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell Required for pre-rRNA processing and maturation of 40S ribosomal subunits ### SEQUENCE -M-P-G-V-T-V-K-D-V-N-Q-Q-E-F-V-R-A-L-A-A-F-L-K-K-S-G-K-L-K-V-P-D-W-V-D-L-V-K-L-G-R-H-K-E-L-A-P-S-D-E-N-W-F-Y-I-R-A-A-S-T-V-R-H-L-Y-L-R-G-G-A-G-V-G-S-M-T-K-I-Y-G-G-R-Q-R-N-G-V-C-P-A-H-Y-S-E-G-S-K-N-V-A-R-K-V-L-Q-A-L-E-L-L-K-M-I-E-K-D-P-N-G-G-R-R-L-T-A-Q-G-T-R-D-L-D-R-I-A-G-Q-V-S-A-A-S-K-K-I-V-Q


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-G-R-M-H-A-P-G-K-G-L-S-Q-S-A-L-P-Y-R-R-S-V-P-T-W-L-K-L-T-S-D-D-V-K-E-Q-I-F-K-L-A-K-K-G-L-T-P-S-Q-I-G-V-I-L-R-D-S-H-G-V-A-Q-V-R-F-V-T-G-N-K-I-L-R-I-L-K-S-K-G-L-A-P-D-L-P-E-D-L-Y-H-L-I-K-K-A-V-A-V-R-K-H-L-E-R-N-R-K-D-K-D-A-K-F-R-L-I-L-I-E-S-R-I-H-R-L-A-R-Y-Y-K-T-K-R-V-L-A-P-N-W-K-Y-X-S-S-T-A-S-A-L-V-A


### FUNCTION Transcriptional activator that mediates FGF signaling during neural development ### SEQUENCE -M-C-G-G-C-V-G-T-E-Y-P-E-R-G-T-T-C-L-E-G-G-S-F-L-L-N-F-V-G-C-A-R-C-G-R-R-D-F-V-L-L-G-N-R-A-A-G-L-H-G-D-D-E-I-I-T-Y-D-H-L-C-K-N-C-H-H-L-I-A-R-H-E-Y-T-F-S-V-V-D-D-Y-Q-E-Y-T-M-L-C-L-L-C-G-R-A-E-D-S-V-S-I-L-P-D-D-P-R-Q-M-T-P-L-F


### FUNCTION Transcriptional activator that mediates FGF signaling during neural development ### SEQUENCE -M-C-G-G-C-V-Q-Q-E-Y-P-D-R-G-S-T-C-L-E-T-G-S-Y-L-L-N-Y-V-S-C-V-Q-C-N-K-R-D-F-V-L-I-V-N-K-T-A-A-E-E-D-G-E-E-I-I-T-Y-D-H-M-C-K-N-C-H-H-V-I-A-K-H-E-Y-T-F-S-V-V-D-D-Y-Q-E-Y-T-M-L-C-M-L-C-G-R-A-E-D-S-V-S-V-L-P-D-D-P-R-Q-M-A-P-L-F


### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-V-V-K-T-W-M-P-W-L-L-V-S-S-V-L-S-Q-G-C-C-Q-H-W-S-F-G-L-S-P-G-G-K-R-E-L-K-Y-F-P-N-T-L-E-N-Q-I-R-L-L-N-S-N-T-P-C-S-D-L-S-H-L-E-E-S-S-L-A-K-I-Y-R-I-K-G-L-L-G-S-V-T-E-A-K-N-G-Y-R-T-Y-K


### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1  with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-K-L-V-P-L-F-Y-K-T-C-P-A-G-K-N-L-C-Y-K-I-F-M-V-A-T-P-K-V-P-V-K-R-G-C-I-D-V-C-P-K-N-S-A-L-V-K-Y-V-C-C-N-T-D-R-C-N


### FUNCTION Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles ### SEQUENCE -M-A-D-L-D-A-V-L-K-C-W-G-A-V-E-A-D-F-N-T-V-G-G-L-V-L-A-R-L-F-K-D-H-P-E-T-Q-K-L-F-P-K-F-A-G-I-T-G-D-I-A-G-N-A-A-V-A-A-H-G-A-T-V-L-K-K-L-G-E-L-L-K-A-K-G-N-H-A-A-I-I-K-P-L-A-N-S-H-A-K-Q-H-K-I-P-I-N-N-F-K-L-I-T-E-A-L-A-H-V-L-H-E-K-A-G-L-D-A-A-G-Q-T-A-L-R-N-V-M-G-I-V-I-A-D-L-E-A-N-Y-K-E-L-G-F-T-G


### FUNCTION Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles ### SEQUENCE -M-A-D-F-D-A-V-L-K-F-W-G-P-V-E-A-D-Y-D-K-I-G-N-M-V-L-T-R-L-F-T-E-H-P-D-T-Q-K-L-F-P-K-F-A-G-I-G-L-G-D-M-A-G-N-A-A-I-S-A-H-G-A-T-V-L-K-K-L-A-E-V-L-K-A-K-G-N-H-A-G-I-I-K-P-L-A-N-S-H-A-T-K-H-K-I-A-I-N-N-F-K-L-I-T-E-I-I-V-K-V-M-Q-E-K-A-G-L-D-A-G-G-Q-T-A-L-R-N-V-M-G-V-F-I-A-D-M-D-A-N-Y-K-E-L-G-F-S-G


### FUNCTION Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles ### SEQUENCE -M-A-D-F-D-A-V-L-K-F-W-G-P-V-E-A-D-Y-T-S-H-G-G-L-V-L-T-R-L-F-K-E-H-P-E-T-Q-K-L-F-P-K-F-T-G-I-A-Q-A-D-M-A-G-N-A-A-I-S-A-H-G-A-T-V-L-K-K-L-G-E-L-L-K-A-K-G-N-H-A-A-I-L-K-P-M-A-N-S-H-A-T-K-H-K-I-P-I-N-N-F-K-L-I-S-E-I-I-V-K-V-M-Q-E-K-A-G-M-D-A-G-G-Q-Q-A-L-R-N-V-M-A-A-V-I-A-D-L-E-A-N-Y-K-E-L-G-F-S-G


### FUNCTION Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles ### SEQUENCE -M-A-D-F-E-M-V-L-K-H-W-G-P-V-E-A-D-Y-A-T-H-G-N-L-V-L-T-R-L-F-T-E-H-P-E-T-Q-K-L-F-P-K-F-A-G-I-A-K-A-D-M-A-G-N-A-A-I-S-A-H-G-A-T-V-L-K-K-L-G-E-L-L-K-A-K-G-S-H-A-A-I-I-K-P-M-A-N-S-H-A-T-K-H-K-I-P-I-K-N-F-E-L-I-S-E-V-I-G-K-V-M-H-E-K-A-G-L-D-A-A-G-Q-K-A-L-K-N-V-M-T-T-I-I-A-D-I-E-A-N-Y-K-E-L-G-F-T-G


### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-I-I-Y-K-D-I-I-T-G-D-E-M-F-S-D-I-Y-K-I-K-E-S-E-N-G-M-M-L-E-V-E-G-K-M-I-T-R-A-E-G-D-I-D-D-A-L-I-G-G-N-A-S-A-E-V-A-D-E-G-C-D-S-T-S-V-S-G-V-D-I-V-L-N-H-K-L-Q-E-T-S-Y-D-K-K-S-Y-T-A-Y-I-K-D-Y-M-K-A-V-K-A-K-L-Q-E-S-A-P-N-R-V-D-P-F-M-A-N-A-P-A-E-V-K-K-I-L-G-N-I-K-N-F-Q-F-F-T-G-E-S-M-N-P-D-G-M-I-G-L-L-D-F-R-E-D-G-V-T-P-Y-M-I-F-F-K-D-G-L-E-I-E-K-C


### FUNCTION NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone ### SEQUENCE -M-H-P-N-M-K-M-W-I-G-W-A-A-C-A-F-L-L-F-A-C-L-G-T-L-T-E-G-Y-P-T-K-P-D-N-P-G-E-D-A-P-A-E-E-L-A-K-Y-Y-S-A-L-R-H-Y-I-N-L-I-T-R-Q-R-Y-G-K-R-S-S-A-D-T-L-I-S-D-L-L-I-G-E-T-E-S-H-P-Q-T-R-Y-E-D-H-L-V-W


### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-N-P-S-S-V-F-L-I-V-V-A-T-V-A-I-C-L-I-V-I-Q-V-Y-Y-I-Y-E-N-Y-D-N-I-K-E-F-N-S-T-H-S-L-L-E-Y-S-K-T-I-N-V-F-S-L-D-R-R-I-Y-D-P-N-D-H-V-H-D-V-K-Q-K-W-R-C-V-N-Y-D-N-N-Y-V-S-V-S-I-F-G-F-K-S-D-S-G-K-N-I-K-N-F-S-T-V-D-D-C-I-D-Y-T-F-S-K-S-T-H-S-N-I-F-N-P-C-I-N-E-D-K-S-K-D-C-N-F-L-K-S-V-L


### FUNCTION Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates Responsible for the transcription of early, intermediate and late genes DNA-dependent RNA polymerase associates with the early transcription factor ### SEQUENCE -M-V-F-Q-L-I-C-S-T-C-G-R-D-I-S-E-E-R-Y-Y-L-L-I-K-E-L-S-L-K-K-V-L-E-G-V-K-N-N-C-C-R-L-K-L-S-T-Q-I-E-P-Q-R-N-L-T-V-Q-P-L-I-D-I-N


### FUNCTION Increases viral DNA accumulation Enhances infectivity and symptom expression ### SEQUENCE -M-D-S-R-T-G-E-L-L-T-A-A-Q-S-E-N-G-V-Y-I-W-T-V-K-N-P-L-Y-F-K-I-T-K-H-H-E-R-P-F-L-R-N-H-D-I-I-T-I-Q-V-Q-F-N-Y-N-L-R-K-A-L-G-I-H-K-C-F-L-T-C-Q-I-W-T-R-L-H-P-Q-T-S-H-F-L-R-V-F-K-Y-Q-F-I-K-Y-L-D-R-L-G-V-I-S-I-N-N-C-I-R-A-F-S-H-V-L-Y-D-V-L-N-G-T-I-D-V-I-E-K-H-D-I-K-F-N-I-Y


### FUNCTION Through its interaction with host SGS3, acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing , a mechanism of plant viral defense that limits the accumulation of viral RNAs ### SEQUENCE -M-W-D-P-L-L-N-E-F-P-E-T-V-H-G-F-R-C-M-L-A-I-K-Y-L-Q-L-V-E-N-T-Y-S-P-D-T-L-G-Y-D-L-I-R-D-L-I-S-V-I-R-A-R-D-Y-G-E-T-S-R-R-Y-C-H-F-H-S-R-L-E-G-A-S-P-A-E-L-R-Q-P-L-Y-G-S-C-C-C-P-H-C-P-R-H-Q-K-T-N-V-V-K-Q-A-H-V-P-E-A-H-D-V-P-D-V-Q-K-P


### FUNCTION Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly ### SEQUENCE -M-S-R-A-S-S-Q-Q-A-S-P-T-S-Q-T-F-D-P-S-D-L-S-T-Y-T-L-D-V-L-H-H-Y-P-L-V-D-L-L-Q-Q-L-N-A-I-P-N-D-L-K-I-P-D-T-Y-S-K-V-E-Q-A-A-R-I-N-V-L-R-A-I-C-V-G-F-A-E-V-R-R-H-N-D-N-R-T-L-Q-R-S-T-M-F-A-V-N-D-A-A-S-R-I-R-P-S-I-G-L-K-R-T-F-P-T-G-I-F-S-T-T-I-H-G-S-P-S-D-D-D-I-S-T-S


### FUNCTION Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm Once the complex reaches the host nucleus, it interacts with the capsid portal vertex This portal forms a ring in which genomic DNA is translocated into the capsid ### SEQUENCE -M-A-G-E-N-T-S-R-R-T-G-S-A-R-L-D-E-V-I-P-E-F-E-L-V-S-T-D-V-K-I-L-A-E-K-Y-L-Q-D-E-R-I-Y-R-I-W-F-E-Y-L-I-P-D-E-I-D-L-I-F-P-T-T-D-G-K-L-N-Y-L-S-F-T-K-R-L-A-S-A-I-R-Y-G-R-I-K-T-A-V-S-N-N-S-S-S-N-S-Y-G-S-T-E-H-V-C-D-H-G-T-S-L-C-G-R-S-E-R-F-A-S-V-I-N-R-F-L-D-L-H-Q-I-L-K-D-C


### FUNCTION Plays a major role in assembly and budding of virion Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form Inhibits viral transcription and stimulates replication ### SEQUENCE -M-S-A-K-L-N-W-Y-R-I-T-F-N-D-T-V-W-R-F-D-T-A-R-G-P-K-D-G-E-T-C-P-L-I-A-S-E-L-F-S-S-G-L-S-E-V-F-K-S-V-T-S-F-S-E-I-L-R-N-M-E-S-R-G-Y-I-T-N-I-T-L-R-A-D-S-D-I-L-G-P-G-A-L-R-C-E-F-L-F-P-S-E-V-F-I-P-T-S-H-T-L-K-M-G-R-S-S-L-I-L-E-P-H-L-V-V-L-K-E-C-K-Y-I-S-S-G-K-L-D-I-G-I-S-S-I-E-A-T-S-V-A-V-L-R-R-V-K-G-P-A-F-I-G-C-M-D-D-N-P-F-G-V-L-T-K-K-P-S-D-E-K-N-V-L-A-S-K


### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-S-D-K-T-V-K-S-T-N-L-M-A-F-I-A-T-K-M-L-E-R-Q-E-D-L-D-T-C-T-E-M-Q-V-E-K-M-K-T-S-T-K-A-R-L-R-T-E-S-S-F-A-P-R-T-W-E-D-A-I-K-D-E-I-L-R-R-S-V-D-T-S-S-L-D-K-W-P-E-L-K-Q-E-L-E-N-V-S-D-A-L-K-A-D-S-L-W-L-P-M-K-S-L-S-L-Y-S-K-V-S-N-Q-E-P-N-S-I-P-I-G-E-M-K-H-Q-I-L-T-R-L-K-L-I-C-S-R-L-E-K-L-D-L-N-L-S-K-A-V-L-G-I-Q-N-S-E-D-L-I-L-I-I-Y-N-R-D-I-C-K-T-T-I-L-M-I-K-S-L-C-N-S-L-I


### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-S-D-K-T-V-K-S-T-N-L-M-A-F-V-A-T-K-M-L-E-R-Q-E-D-L-D-T-C-T-E-M-Q-V-E-K-M-K-T-S-T-K-A-R-L-R-T-E-S-S-F-A-P-R-T-W-E-D-A-I-K-D-E-I-L-R-R-S-V-D-T-S-S-L-N-K-W-P-E-L-K-Q-E-L-E-N-V-S-D-A-L-K-A-D-S-L-W-L-P-M-K-S-L-S-L-Y-S-K-V-S-N-Q-E-P-S-S-I-P-I-G-E-M-K-H-Q-I-L-T-R-L-K-L-I-C-S-R-L-E-K-L-D-L-N-L-S-K-A-V-L-G-I-Q-N-S-E-D-L-I-L-I-I-Y-N-R-D-V-C-K-N-T-I-L-M-I-K-S-L-C-N-S-L-I


### FUNCTION Has antibacterial activity ### SEQUENCE -M-K-I-H-Y-L-L-F-A-F-L-L-V-L-L-S-P-L-A-G-V-F-S-K-T-I-N-N-P-V-S-C-C-M-I-G-G-I-C-R-Y-L-C-K-G-N-I-L-Q-N-G-S-C-G-V-T-S-L-N-C-C-K-R-K


### FUNCTION Promotes cell adhesion to laminin and fibronectin ### SEQUENCE -M-A-K-N-G-L-V-L-C-I-L-V-V-S-L-L-L-D-Q-T-D-G-Y-P-S-R-M-K-A-R-K-H-S-K-R-R-V-K-A-K-D-D-D-L-K-S-Q-V-E-K-L-W-R-E-V-N-A-L-K-E-M-Q-A-L-Q-T-V-C-L-R-G-T-K-V-H-K-K-C-Y-L-A-S-E-G-L-K-H-Y-H-E-A-N-E-D-C-I-S-K-G-G-T-L-V-V-P-R-N-S-D-E-I-N-A-L-R-D-Y-G-K-R-S-L-P-G-V-N-D-F-W-L-G-I-N-D-M-V-T-E-G-K-F-L-D-V-H-G-F-A-V-S-F-L-N-W-D-R-A-Q-P-S-G-G-K-R-E-N-C-V-L-F-S-Q-S-A-Q-G-K-W-S-D-E-A-C-R-S-S-K-R-Y-I-C-E-F-I-I-P


### FUNCTION Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1 ### SEQUENCE -M-D-W-P-H-S-L-L-F-L-L-A-I-S-I-F-L-G-P-S-Q-P-R-N-T-K-G-K-R-K-G-Q-V-R-P-G-P-L-A-P-G-P-H-Q-V-P-L-D-L-V-S-R-V-K-P-Y-A-R-M-E-E-Y-E-R-N-L-G-E-M-V-A-Q-L-R-N-S-S-E-P-A-K-R-R-C-E-V-N-L-Q-L-W-L-S-N-K-R-S-L-S-P-W-G-Y-S-I-N-H-D-P-S-R-I-P-A-D-L-P-E-A-R-C-L-C-L-G-C-V-N-P-F-T-M-Q-E-D-R-S-M-V-S-V-P-V-F-S-Q-V-P-V-R-R-R-L-C-P-P-P-P-R-P-G-P-C-R-H-R-V-V-M-E-T-I-A-V-G-C-T-C


### FUNCTION Probable transcription factor involved in the control of specification of mesoderm and endoderm ### SEQUENCE -M-A-S-P-V-E-A-S-P-G-C-A-S-G-L-G-P-H-R-R-K-R-T-T-F-S-V-G-Q-L-L-E-L-E-R-V-F-A-A-R-P-Y-P-D-I-S-T-R-E-H-L-A-Q-I-T-H-L-P-E-A-K-I-Q-V-W-F-Q-N-R-R-A-K-R-I-K-D-R-K-P-G-A-L-N-A-R-L-E-L-P-P-N-C-S-L-P-D-T-P-Q-L-S-W-D-P-G-T-P-S-H-P-L-H-S-T-S-S-A-Q-Q-T-S-A-C-P-P-Q-T-S-C-L-A-P-I-L-G-P-G-Q-S-W-S-G-A-K-A-A-A-P-W-G-T-S-E-V-S-G-V-H-S-L-E-Q-I-V-P-Q-T-S-L-G-N-L-S-D-L-I-Y-T-S-A-I-V-T-N-V-D-H-S


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-E-I-T-V-E-L-V-S-V-E-R-M-L-W-A-G-Q-A-S-I-V-T-A-Q-T-T-E-G-E-I-G-V-L-P-D-H-E-P-L-L-G-Q-L-V-E-N-G-V-V-T-I-Q-P-I-D-G-E-K-L-I-A-G-V-S-D-G-F-L-S-V-S-K-E-K-V-T-I-L-A-D-F-A-V-W-A-N-E-V-D-T-A-S-A-E-A-D-L-N-S-D-D-E-L-A-K-A-H-A-E-A-G-L-R-A-V-R-R-S-S-E-G-L


### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation ### SEQUENCE -M-N-W-I-V-I-D-T-V-I-Q-P-A-C-D-I-S-F-S-A-I-W-C-N-I-K-L-I-L-W-Y-Q-S-D-I-F-L-P-P-G-C-I-F-T-P-T-R-T-G-V-I-L-N-N-K-E-L-P-V-T-I-Y-N-V-T-P-F-N-K-N-V-W-N-L-I-K-S-S-Q-E-C-P-A-N-T-G-N-I-T-D-K-C-F-N-H-R-C-I-L-E-I-C-P-Y-G-R-K


### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-S-T-L-A-K-I-E-A-L-L-F-V-R-G-E-D-W-I-R-V-R-Q-L-A-E-L-L-S-L-P-P-T-G-I-Q-Q-S-L-E-K-L-S-Q-K-Y-E-K-D-L-D-S-S-L-D-L-I-E-T-G-G-A-Y-R-L-V-T-K-P-Q-F-S-E-I-L-K-E-Y-S-K-A-P-I-N-Q-S-L-S-R-P-A-L-E-T-L-S-I-I-A-Y-K-Q-P-I-T-R-I-E-I-D-A-I-R-G-V-N-S-S-G-A-L-A-K-L-Q-A-F-D-L-I-R-E-D-G-K-K-E-V-L-G-R-P-N-L-Y-V-T-T-D-Y-F-L-D-Y-M-G-I-N-H-L-E-E-L-P-V-I-D-E-L-E-I-Q-A-Q-E-S-Q-L-F-G-E-R-I-E-E-D-E-N-Q


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-S-G-K-G-A-P-E-L-S-V-R-N-V-G-D-L-R-V-A-V-I-A-S-Q-W-H-D-K-V-M-D-G-L-V-D-G-A-L-R-A-L-H-E-L-G-I-D-E-P-T-L-L-R-V-P-G-S-F-E-L-P-V-V-A-K-V-L-A-G-R-G-Y-D-A-I-V-A-L-G-V-V-I-R-G-G-T-P-H-F-D-Y-V-C-Q-G-V-T-Q-G-L-V-Q-V-S-V-E-T-G-V-P-V-G-F-G-V-L-T-C-D-T-E-E-Q-A-L-D-R-A-G-I-E-G-S-S-E-D-K-G-H-E-A-V-T-A-A-V-A-T-A-A-T-L-R-S-V-S-E-P-W-R


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-G-S-V-R-K-A-S-A-W-L-G-L-V-D-D-N-N-D-D-E-R-Y-Y-D-D-D-Y-S-E-G-P-E-S-G-D-A-W-V-T-D-P-R-V-K-V-A-S-D-V-A-E-E-K-G-R-R-I-A-T-V-T-P-D-S-F-R-D-A-R-A-I-G-E-L-F-R-D-G-V-P-V-I-V-N-L-T-A-M-E-G-T-D-A-K-R-V-V-D-F-A-A-G-L-I-F-G-L-R-G-S-I-E-R-V-S-T-R-V-F-L-L-S-P-A-D-T-Q-V-I-S-G-E-S-A-A-H-R-S-D-G-F-F-N-Q-S


### FUNCTION Involved in protein export Participates in an early event of protein translocation ### SEQUENCE -M-D-A-I-Q-I-V-M-F-V-M-A-I-L-C-L-I-I-G-L-L-L-S-N-H-G-S-T-G-G-L-A-S-L-S-G-Q-D-L-E-I-F-R-K-T-K-D-R-G-I-V-K-I-L-Q-I-T-M-F-I-L-V-V-L-F-L-I-L-G-L-V-F-H-F-A-L


### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-R-I-S-D-A-A-Q-A-H-F-A-K-L-L-A-N-Q-E-E-G-T-Q-I-R-V-F-V-I-N-P-G-T-P-N-A-E-C-G-V-S-Y-C-P-P-D-A-V-E-D-T-D-T-A-L-K-F-E-Q-L-T-A-Y-V-D-E-L-S-A-P-Y-L-E-D-A-E-I-D-F-V-T-D-Q-L-G-S-Q-L-T-L-K-A-R-T-P-K-C-A-K


### FUNCTION Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone  biosynthetic pathway ### SEQUENCE -M-T-A-D-A-P-V-I-S-G-S-S-V-V-K-L-A-R-G-V-R-L-H-E-D-P-V-R-G-Q-T-V-L-L-A-P-E-R-A-M-A-V-D-D-I-A-V-A-I-V-Q-A-L-D-G-E-R-N-L-D-R-I-A-A-D-F-A-E-K-F-D-A-P-V-E-E-I-A-E-D-V-R-T-F-V-Q-E-L-S-V-R-R-M-L-E-I-V-Q


### FUNCTION Required for coenzyme pyrroloquinoline quinone ### SEQUENCE -M-A-W-H-K-P-K-F-I-E-V-S-C-A-M-E-I-T-R-Y-A-P-A-D-G-D-E-P-I-L-F


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-F-G-I-T-Q-N-I-V-A-I-V-T-E-H-A-K-G-A-K-V-Q-R-V-L-L-E-I-G-K-L-S-A-I-M-P-D-A-I-R-F-C-F-D-I-C-T-Q-G-T-V-L-E-G-A-T-L-E-I-L-E-I-P-G-L-G-R-C-R-Q-C-G-G-E-I-Y-L-D-K-P-F-G-I-C-N-C-G-S-V-Q-L-D-L-I-T-G-E-E-L-K-I-K-E-I-E-I-E-E-L-C-V


### FUNCTION General  is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-E-Q-K-S-Y-V-I-I-D-E-T-G-I-H-A-R-P-A-T-M-L-V-Q-T-A-S-K-F-D-S-D-I-Q-L-E-Y-N-G-K-K-V-N-L-K-S-I-M-G-V-M-S-L-G-V-G-K-D-A-E-I-T-I-Y-A-D-G-S-D-E-T-D-A-I-E-A-I-T-D-I-L-S-K-E-G-L-T-K


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-G-K-L-T-L-L-L-L-A-L-L-V-W-L-Q-Y-S-L-W-F-G-K-N-G-L-H-D-Y-T-R-V-N-D-D-V-T-A-Q-Q-A-T-N-A-K-L-K-A-R-N-D-Q-L-F-A-E-I-D-D-L-N-G-G-Q-E-A-I-E-E-R-A-R-N-E-L-S-M-T-R-P-G-E-T-F-Y-R-L-V-P-D-A-S-K-R-N-Q-A-S-G-Q-Q-Q-N-N-R


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-I-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-I-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-N-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-P-V-N-H-H-H-A-S-D-R-P-A-T-L-E-K-T-E-E


### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-G-N-N-F-N-A-S-N-A-D-T-D-H-L-P-Q-V-S-I-L-A-Q-Y-I-K-D-L-S-F-E-N-P-N-A-P-A-V-Y-Q-W-Q-T-Q-P-H-I-E-V-Q-F-N-I-G-T-Q-P-M-A-Q-D-V-Y-E-V-A-L-K-V-D-V-S-A-K-A-D-E-G-V-V-F-H-V-E-L-V-Y-N-G-L-F-A-I-K-N-V-P-A-D-Q-I-Q-P-F-L-Y-I-E-A-P-R-I-L-F-P-F-V-R-R-I-L-A-D-S-V-R-D-G-N-F-P-P-L-M-L-E-P-I-D-F-A-A-L-Y-M-Q-Q-T-E-Q-Q-D-M-L-S-N-T-E-P-A-G-Q-A


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-T-I-E-E-R-V-K-K-I-V-V-E-Q-L-G-V-K-E-E-E-V-T-N-S-A-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-E-C-E-I-P-D-E-E-A-E-K-I-T-S-V-Q-Q-A-I-D-Y-V-K-V-H-V-K-S


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-M-K-V-I-P-L-G-E-R-L-L-I-K-P-I-K-E-E-K-K-T-E-G-G-I-V-L-P-D-S-A-K-E-K-P-M-K-A-E-V-V-A-V-G-K-I-E-D-E-E-K-F-D-I-K-V-G-D-K-V-I-F-S-K-Y-A-G-T-E-I-K-I-D-D-E-D-Y-I-I-I-D-V-N-D-I-L-A-K-I-E-E


### FUNCTION Major structural protein of the hrp pilus, which is a component of the type III secretion system ### SEQUENCE -M-N-I-M-S-S-L-T-N-A-G-R-G-V-V-N-T-V-G-G-A-A-Q-G-I-N-S-V-K-S-S-A-D-R-N-I-A-L-T-K-N-T-G-S-T-D-S-I-D-A-T-R-S-S-I-S-K-G-D-A-K-S-A-E-L-D-G-T-A-N-E-E-N-G-L-L-R-E-T-S-M-L-A-G-F-E-D-K-K-E-A-L-S-N-Q-I-V-A-S-K-I-R-N-S-V-V-Q-F


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-L-C-M-S-A-A-D-I-I-R-E-Q-A-E-Q-H-G-I-A-R-V-T-D-V-W-L-E-V-G-A-L-A-D-V-E-E-S-A-L-H-F-C-F-D-I-A-C-R-D-T-V-A-Q-G-C-T-L-H-I-D-V-I-P-A-Q-A-W-C-W-D-C-S-R-E-A-E-I-M-Q-H-A-G-C-C-P-H-C-G-S-E-R-L-R-I-T-E-G-D-D-L-R-V-K-S-L-E-G-E


### FUNCTION Involved in the stabilization of the sigma stress factor RpoS ### SEQUENCE -M-E-W-K-V-V-D-T-V-I-S-P-S-T-G-V-S-F-S-C-I-H-S-L-K-N-L-R-L-T-L-W-Y-Q-A-D-V-Y-M-P-P-G-S-I-I-I-P-F-N-K-G-V-L-I-N-D-K-L-Y-P-V-T-V-Y-N-V-T-R-F-N-P-V-L-W-K-S-L-K-E-N-S-H-C-P-G-N-C-N-P-K-S-E-A-C-S-Y-P-F-E-C-L-V-S-V-C-P-F-G-L-T-R-N-I-Q-I-D-N-K-K-V


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-L-T-K-A-E-L-A-D-I-L-V-D-K-V-S-N-V-T-K-N-S-A-K-E-I-V-E-L-F-F-E-E-I-R-S-T-L-A-S-G-E-E-I-K-I-S-G-F-G-N-F-Q-L-R-D-K-P-Q-R-P-G-R-N-P-K-T-G-E-E-V-P-I-T-A-R-R-V-V-T-F-H-A-S-Q-K-L-K-G-M-V-E-H-Y-Y


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-L-L-H-D-R-V-I-V-K-R-K-E-M-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-E-V-I-A-V-G-K-G-R-V-L-E-N-G-N-I-Q-P-L-D-V-K-I-G-D-T-I-I-F-N-D-G-Y-S-V-K-V-E-K-I-D-N-Q-D-V-L-I-M-S-E-S-D-I-L-A-I-V-E-E


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-K-R-K-E-V-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-E-I-I-A-V-G-K-G-R-V-L-E-N-G-N-T-Q-P-L-D-V-K-I-G-D-T-V-I-F-N-D-G-Y-G-V-K-V-E-K-I-D-N-Q-D-M-L-I-M-S-E-S-D-I-L-A-I-V-E-A


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-I-K-R-Q-E-S-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-T-V-L-A-V-G-N-G-R-I-L-D-N-G-S-V-K-S-L-D-V-K-V-G-D-V-V-I-F-N-E-G-Y-G-A-K-T-E-K-M-D-H-E-E-V-L-I-L-T-E-S-D-I-L-A-I-V-E-E


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-I-K-R-Q-E-V-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-I-V-T-A-V-G-N-G-R-V-L-D-N-G-E-L-K-A-L-D-V-K-I-G-D-T-V-I-F-S-E-G-Y-G-A-K-I-E-K-I-D-N-E-E-F-L-I-L-T-E-S-D-I-L-A-V-V-E-D


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-L-V-K-R-Q-E-V-E-L-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-T-V-V-A-V-G-K-G-R-I-L-D-N-G-E-T-K-S-L-D-V-K-I-G-D-V-V-I-F-N-E-G-Y-G-A-K-T-E-K-I-D-N-E-E-L-L-I-L-T-E-S-D-I-L-A-I-V-E-E


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-I-R-P-L-H-D-R-V-I-V-K-R-K-E-A-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-G-K-S-T-R-G-T-V-T-A-V-G-N-G-R-I-L-D-N-G-S-I-K-P-L-D-V-K-V-G-E-T-V-I-F-N-E-G-Y-G-A-K-I-E-K-I-D-N-E-E-L-L-I-L-T-E-S-D-I-L-A-I-V-E-E


### FUNCTION Involved in the antibiotic teicoplanin susceptibility Inactivation of the tcaRAB operon leads to teicoplanin resistance ### SEQUENCE -M-V-K-H-L-Q-D-H-I-Q-F-L-E-Q-F-I-N-N-V-N-A-L-T-A-K-M-L-K-D-L-Q-N-E-Y-E-I-S-L-E-Q-S-N-V-L-G-M-L-N-K-E-P-L-T-I-S-E-I-T-Q-R-Q-G-V-N-K-A-A-V-S-R-R-I-K-K-L-I-D-A-K-L-V-K-L-D-K-P-N-L-N-I-D-Q-R-L-K-F-I-T-L-T-D-K-G-R-A-Y-L-K-E-R-N-A-I-M-T-D-I-A-Q-D-I-T-N-D-L-N-S-E-D-I-E-N-V-R-Q-V-L-E-V-I-N-H-R-I-K-T-Y-S-N-H-K


### FUNCTION Regulates the transcription of the pyrimidine nucleotide  operon in response to exogenous pyrimidines ### SEQUENCE -M-S-L-P-N-P-A-E-L-I-S-Q-M-A-I-R-L-K-A-H-L-E-H-R-G-I-S-D-P-R-Y-I-G-I-R-T-G-G-V-W-V-A-Q-A-L-L-E-A-L-G-S-Q-S-P-L-G-T-L-D-V-S-F-Y-R-D-D-F-S-Q-N-G-L-H-P-Q-V-R-P-S-A-L-P-F-E-I-E-G-Q-H-L-V-L-I-D-D-V-L-M-S-G-R-T-I-R-A-A-M-N-E-L-F-D-Y-G-R-P-A-S-V-T-L-V-C-L-L-D-L-D-A-A-E-L-P-I-R-P-N-V-V-G-A-T-L-T-L-A-A-H-E-R-V-K-L-S-G-P-S-P-L-Q-L-E-L-Q-D-L-A-L


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-L-R-L-L-L-G-F-D-Y-G-T-K-Q-I-G-V-A-V-G-Q-V-I-T-G-Q-A-R-E-L-C-T-L-K-A-Q-N-G-V-P-D-W-N-Q-V-E-A-L-I-K-E-W-K-P-D-A-V-V-V-G-L-P-L-N-M-D-G-T-P-S-D-M-C-L-R-A-E-K-F-A-R-R-L-N-G-R-Y-N-L-P-F-Y-T-H-D-E-R-L-T-T-F-E-A-K-G-E-R-L-V-R-G-G-Q-K-G-S-Y-R-D-N-P-V-D-A-I-A-A-A-L-L-L-Q-G-W-L-D-A-N-A-A-L-F-E-T


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-I-T-K-E-D-I-L-E-A-V-G-S-L-T-V-M-E-L-N-D-L-V-K-A-F-E-E-K-F-G-V-S-A-A-A-V-A-V-A-G-P-A-G-A-G-A-A-A-A-E-E-K-T-E-F-D-V-V-L-A-S-A-G-D-Q-K-V-G-V-I-K-V-V-R-A-I-T-G-L-G-L-K-E-A-K-D-I-V-D-G-A-P-K-T-L-K-E-G-V-S-K-A-E-A-E-D-I-Q-K-Q-L-E-E-A-G-A-K-V-E-I-K


### FUNCTION Has a post-transcriptional repressor function in flagellum biogenesis Associates with the 5'-UTR of fljK mRNA and promotes its degradation ### SEQUENCE -M-K-S-T-L-R-I-S-L-K-S-G-E-R-I-F-V-N-G-A-V-L-R-V-D-R-K-V-A-I-E-F-L-N-D-V-T-F-L-L-E-N-H-V-L-Q-P-E-D-A-T-T-P-L-R-Q-L-Y-F-I-A-Q-M-I-L-I-N-P-E-G-A-D-Q-S-T-A-M-F-R-K-S-I-V-M-L-L-N-C-F-K-H-D-E-V-L-A-E-L-K-R-I-D-G-L-V-T-Q-G-R-A-F-E-A-L-K-A-I-R-G-L-Y-P-I-E-D-Q-I-L-N-A-Q-E-L-T-P-A-T-V-E-Q-I-R-K-E-I-A-P-W-R


### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-V-L-T-R-K-V-G-E-S-L-L-I-G-D-D-I-E-I-T-V-L-S-V-R-G-N-Q-V-K-L-G-V-N-A-P-K-N-I-V-V-H-R-E-E-I-Y-H-Q-I-K-A-L-A-D-N-I-P-E-S-V


### FUNCTION Transcription regulator that can specifically activate or repress expression of target genes ### SEQUENCE -M-E-S-T-L-G-S-D-L-S-R-L-V-R-V-W-R-A-L-I-D-Q-R-L-K-P-L-E-L-T-Q-T-H-W-V-T-L-Y-N-I-H-R-L-P-P-D-Q-S-Q-I-Q-L-A-K-A-I-G-I-E-Q-P-S-L-V-R-T-L-D-Q-L-E-D-K-G-L-I-T-R-H-I-C-A-N-D-R-R-A-K-R-I-K-L-T-D-D-A-E-P-V-I-K-E-V-T-G-V-I-S-L-T-R-S-E-I-L-D-G-I-S-T-D-E-I-A-L-L-T-N-L-V-E-R-L-E-Q-N-I-I-H-L-Q-N-K


### FUNCTION Dephosphorylates Wzc Required for the extracellular polysaccharide colanic acid synthesis Probably involved in the export of colanic acid from the cell to medium Involved in protection of cells against contact-dependent growth inhibition ### SEQUENCE -M-F-N-K-I-L-V-V-C-V-G-N-V-C-R-S-P-T-A-E-R-L-L-K-R-F-H-P-S-L-T-V-A-S-A-G-L-G-A-L-V-G-K-G-A-D-P-A-A-A-S-V-A-S-A-H-D-L-S-L-E-N-H-C-A-R-Q-I-S-A-R-L-C-R-E-Y-D-L-I-L-T-M-E-K-R-H-I-A-A-L-C-D-I-A-P-E-M-R-G-K-V-M-L-F-G-H-W-D-S-E-R-E-I-P-D-P-Y-R-K-S-R-D-A-F-E-A-V-Y-T-L-L-E-R-S-A-R-Q-W-A-Q-A-L-N-A-E-Q-G-K-P


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-G-S-K-I-P-L-P-Q-Y-E-T-K-G-S-A-G-L-D-L-R-A-C-L-D-S-N-L-S-L-Q-A-G-T-S-Q-L-I-P-I-G-F-A-M-Y-L-E-D-P-G-L-A-A-M-V-I-P-R-S-G-L-G-S-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-E-L-M-V-P-A-W-N-R-S-D-T-D-F-E-I-N-P-G-D-R-I-A-Q-M-I-I-V-P-V-I-Q-A-D-F-E-I-V-D-E-F-N-E-T-Q-R-G-E-K-G-F-G-S-S-G-I-N


### FUNCTION Toxic component of a type II toxin-antitoxin  system Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA Neutralized by coexpression with cognate antitoxin MazE ### SEQUENCE -M-I-R-R-G-D-V-Y-L-A-D-L-S-P-V-Q-G-S-E-Q-G-G-V-R-P-V-V-I-I-Q-N-D-T-G-N-K-Y-S-P-T-V-I-V-A-A-I-T-D-G-I-N-K-A-K-I-P-T-H-V-E-I-E-K-K-K-Y-K-L-D-K-D-S-V-I-L-L-E-Q-I-R-T-L-D-K-K-R-L-K-E-K-L-T-F-L-S-E-S-K-M-I-E-V-D-N-A-L-D-I-S-L-G-L-N-N-F-D-H-H-K-S


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-F-I-I-A-G-L-G-N-P-G-Q-E-Y-E-N-T-R-H-N-A-G-F-M-V-V-D-E-L-A-K-K-H-G-I-L-I-T-K-R-K-F-K-S-L-V-G-E-G-E-I-L-G-V-K-V-L-L-L-K-P-Q-T-Y-M-N-L-S-G-T-A-V-Q-E-A-V-S-F-Y-K-L-P-L-S-R-L-V-V-V-Y-D-D-L-D-L-P-L-G-K-I-R-L-R-L-K-G-S-A-G-G-H-R-G-M-G-S-I-I-S-C-L-G-S-E-E-I-P-R-L-K-I-G-I-G-R-P-A-V-G-D-V-K-D-Y-V-L-Q-P-F-T-G-A-E-R-E-I-L-E-P-T-L-K-L-A-A-E-A-I-T-V-A-L-T-E-G-F-N-K-A-M-T-D-F-N-R-G-G


### FUNCTION Involved in the temperature-dependent positive control of flagellum-driven swimming motility and cellular aggregation Regulates fliC expression by directly interacting with fliC promoter ### SEQUENCE -M-A-L-R-N-K-A-F-H-Q-L-R-Q-L-F-Q-Q-H-T-A-R-W-Q-H-E-L-P-D-L-T-K-P-Q-Y-A-V-M-R-A-I-A-D-K-P-G-I-E-Q-V-A-L-I-E-A-A-V-S-T-K-A-T-L-A-E-M-L-A-R-M-E-N-R-G-L-V-R-R-E-H-D-P-A-D-K-R-R-R-F-V-W-L-T-A-E-G-E-K-I-L-A-A-A-I-P-I-G-D-S-V-D-E-E-F-L-G-R-L-S-G-E-E-Q-E-L-F-M-Q-L-V-R-K-M-M-N-A


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-V-I-L-L-E-R-I-S-K-L-G-Q-M-G-E-T-V-K-V-R-D-G-F-A-R-N-Y-L-L-P-L-G-K-A-L-R-A-N-A-A-N-K-T-R-F-E-A-E-R-A-T-L-E-A-R-N-L-E-R-K-S-E-A-Q-K-V-A-D-V-L-D-G-K-S-F-I-V-V-R-S-A-G-E-T-G-Q-L-Y-G-S-V-A-A-R-D-V-V-E-I-L-G-A-E-G-F-N-I-G-R-N-Q-V-H-L-N-T-P-I-K-S-I-G-L-H-K-V-E-L-Q-L-H-A-E-V-E-I-H-V-E-L-N-V-A-R-S-A-E-E-A-E-R-Q-A-K-G-E-E-L-T-S-V-D-A-I-Y-G-V-D-E-D-A-L-R-P-E-D-F-F-D-P-E-A-D-G-V-D-E-D-E-A


### FUNCTION Catalyzes the interconversion of L-alanine and D-alanine May also act on other amino acids ### SEQUENCE -N-S-A-A-I-F-N-F-S-Y-E-R-Y-D-W-V-R-P-G-I-M-L-Y-G-I-S-P-F-A-D-K-N-G-V-D-L-E-L-Q-P-V-M-H-V-V-S-R-L-I-S-V-K-Q-L-R-Q-G-E-S-V-G-Y-G-A-T-W-Q-C-P-E-D-M-Q-V-G-I-L-S-L-G-Y-G-D-G-Y-P-R-L-A-A-S-G-T-P-F-L-V-R-G-Q-R-C-A-L-I-G-R-V-S-M-D-M-I-A-I-D-L-R-R-C-P-D-A-G-V-G-E-A-V-T-V-W-G-Q-D-L-P-V-E-E-I-A-R-H-V-G-T-I-A-Y-E-L-V-C-N-M-P-L-R-A-P-Y-I-W-Q-E


### FUNCTION Required for coenzyme pyrroloquinoline quinone ### SEQUENCE -M-W-T-K-P-S-Y-T-D-L-R-I-G-F-E-V-T-L-Y-F-A-N-R


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-E-Q-K-I-R-V-K-L-K-A-F-D-I-E-L-I-D-Q-S-A-Q-S-I-V-A-S-V-K-K-T-G-A-R-V-S-G-P-I-P-L-P-T-S-I-R-K-V-T-V-I-R-S-P-H-V-N-I-K-S-R-E-Q-F-E-M-R-V-Y-K-R-L-I-D-I-F-D-V-T-P-Q-T-T-E-S-L-K-K-L-A-L-P-A-G-V-D-V-Q-L-K


### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-M-G-I-L-D-E-L-R-G-L-S-A-A-E-D-F-F-R-T-L-G-V-K-Y-D-A-E-V-L-N-V-A-R-L-H-I-L-R-R-M-G-T-Y-L-S-Q-A-E-L-E-P-D-E-D-A-A-R-A-Q-C-R-A-Q-L-Q-R-A-Y-D-D-F-T-R-S-T-P-I-A-E-R-V-F-K-V-H-R-D-A-V-R-P-S-G-G-F-V-S-L-S-E-L-T-Q-D-G-T


### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-R-F-T-Q-V-I-N-S-E-G-R-D-N-F-T-D-R-E-N-C-L-I-V-C-L-T-M-D-E-R-T-K-S-R-L-K-V-C-L-N-N-G-D-E-A-G-L-F-L-P-R-G-T-V-L-K-E-G-D-L-L-Q-A-E-T-G-E-I-A-L-V-E-A-A-E-E-V-V-S-T-A-F-T-D-D-L-L-L-L-A-K-A-C-Y-H-L-G-N-R-H-V-P-L-Q-V-E-L-G-W-C-R-Y-L-H-D-H-V-L-D-D-M-V-K-G-L-G-L-G-V-R-V-E-R-A-K-Y-Q-P-E-P-G-A-Y-G-G-S-I-S-G-A-S-H-G-H-H-H-H


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-N-D-I-G-A-L-E-L-V-T-L-V-V-L-A-V-L-V-F-G-P-D-K-L-P-K-V-I-Q-D-V-T-R-T-I-R-K-I-R-E-F-S-D-S-A-K-Q-D-I-R-Q-E-L-G-P-E-F-K-D-F-E-F-E-D-L-N-P-K-T-F-I-R-K-Q-L-D-N-E-E-L-G-L-K-E-I-R-N-G-F-D-L-K-K-E-M-A-E-V-T-D-A-V-H-G-R-D-A-E-S-S-S-S-G-S-S-S-G-S-S-S-A-A-S-G-N-G-R-V-D-M-S-K-K-P-E-K-P-E-K-P-G-K-T-D-K-P-A-A-D-D-R-P-P-F-D-M-D-A-T


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-T-S-E-V-E-Q-P-T-A-M-S-E-A-L-G-Y-E-Q-A-R-D-E-L-I-E-V-V-R-R-L-E-A-G-G-T-T-L-E-E-S-L-A-L-W-E-R-G-E-E-L-A-E-V-C-R-R-R-L-D-G-A-R-A-R-L-D-A-A-L-A-E-E-A-D-P-E-D-G-A-S-G-A-D-G-G-G-A


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-W-L-L-V-V-A-G-G-M-I-G-A-P-L-R-Y-L-T-D-R-A-V-Q-S-R-H-D-S-V-F-P-W-G-T-F-T-V-N-V-I-G-S-V-V-L-G-L-L-T-G-A-A-L-A-G-A-V-G-S-D-L-R-L-L-L-G-T-G-L-C-G-A-L-T-T-Y-S-T-F-S-Y-E-T-L-R-L-T-E-T-G-A-R-L-H-A-A-V-N-V-G-G-S-V-A-A-G-L-V-A-A-F-A-G-V-T-L-A-D-A-L-W-A


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-T-V-P-R-T-G-R-P-G-G-I-R-A-A-A-P-S-R-S-G-W-R-T-Q-A-P-V-V-A-V-V-A-L-G-G-G-T-G-A-A-A-R-Y-A-A-S-L-W-W-P-T-P-A-G-G-F-P-W-T-T-F-G-V-N-A-V-G-C-A-V-I-G-V-F-M-V-V-I-T-E-V-R-P-A-H-R-L-V-R-P-F-F-G-T-G-V-L-G-G-F-T-T-F-S-T-Y-A-V-D-S-R-S-L-F-A-D-G-R-L-P-T-G-L-A-Y-L-A-A-T-P-L-A-A-L-T-A-V-W-L-A-A-W-A-A-R-R-V-L-K-W-R-Q-S


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-Y-G-I-G-I-D-I-T-N-I-D-R-F-K-A-L-H-N-P-T-S-F-I-K-K-V-L-T-D-K-E-Q-A-E-L-A-G-K-S-G-Q-R-A-Y-E-F-L-A-G-H-F-S-V-K-E-S-Y-S-K-A-Y-G-T-G-L-G-K-K-L-N-F-Q-D-I-E-V-E-Y-D-D-N-G-R-P-V-I-S-N-H-P-F-A-G-V-A-H-V-S-I-S-H-S-K-H-H-V-V-T-Q-V-I-L-E-G-D


### FUNCTION Major structure protein of the hrp pilus, which is a component of the type III secretion system ### SEQUENCE -M-G-L-G-G-P-L-S-S-A-T-S-F-A-S-K-T-L-E-G-A-M-S-D-S-M-A-E-S-A-V-A-Q-A-A-K-M-K-I-D-T-Q-N-S-I-L-D-G-K-M-D-S-A-T-K-E-I-N-S-G-H-N-A-A-K-A-I-Q-F


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-I-K-T-G-G-K-Q-Y-K-V-A-V-G-E-K-L-K-V-E-Q-I-P-A-D-I-D-A-E-I-T-L-D-Q-V-L-A-V-G-E-G-E-S-I-Q-F-G-T-P-L-V-S-G-A-S-V-K-A-T-V-V-S-H-G-R-H-A-K-V-T-I-F-K-M-R-R-R-K-H-Y-Q-K-H-G-G-H-R-Q-N-Y-T-E-L-R-I-D-A-I-N-A


### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate  for the ubiquinone pathway ### SEQUENCE -M-Q-V-V-Y-N-F-S-Q-P-G-L-Q-W-K-Q-S-D-H-L-R-S-L-M-T-V-T-S-R-D-W-L-L-D-R-G-S-L-T-R-R-L-R-V-L-S-D-D-D-L-E-V-V-P-L-R-E-E-V-G-V-I-L-P-H-E-A-D-V-L-G-L-Q-L-G-A-I-G-G-V-R-E-V-Y-L-V-G-F-G-R-P-W-V-F-A-R-S-I-I-V-N-S-G-S-I-E-E-G-S-A-L-L-Q-L-G-N-M-P-L-G-D-L-L-F-G-D-G-S-F-Q-R-S-E-I-E-V-C-R-Y-H-D-A-C-N-A-S-A-R-S-T-Y-P-L-W-A-R-R-S-V-F-K-R-E-K-M-H-V-L-V-Q-E-M-F-L-P-A-L-W-E-E-M-S


### FUNCTION Provides oxygen to the bacteroids This role is essential for symbiotic nitrogen fixation ### SEQUENCE -M-G-F-T-A-Q-Q-E-A-L-V-G-S-S-Y-E-T-F-K-K-N-L-P-T-N-S-V-L-F-Y-T-V-I-L-E-I-A-P-T-A-K-D-M-F-S-F-L-K-E-S-G-P-K-H-S-P-Q-L-Q-A-H-A-E-K-V-F-A-L-T-R-D-A-A-T-Q-L-V-A-K-G-E-V-T-L-A-D-A-S-L-G-A-V-H-V-Q-K-A-V-T-D-P-H-F-V-V-V-K-E-A-L-L-Q-T-V-K-E-A-V-G-A-D-E-W-S-D-D-L-S-T-A-W-E-G-A-Y-D-G-L-A-T-A-I-K-K-A-M-G


### FUNCTION Involved in the infection process during the plant-rhizobium interaction ### SEQUENCE -M-A-S-F-F-L-Y-S-L-G-L-V-F-L-S-A-L-T-L-V-P-L-G-L-A-D-K-S-P-S-H-N-M-P-P-N-P-I-Y-T-T-P-I-H-K-N-P-T-N-T-P-V-Y-N-P-P-I-Y-K-P-P-P-T-Y-K-P-P-I-K-K-Q-P-I-N-K-S-P-N-K-K-P-L-L-L-K-P-P-L-P-K-P-P-H-K-E-P-P-S-R-K-R-P-I-N-T-P-P-D-K-K-P-P-L-L-K-P-P-F-P-K-P-P-Q-K-K-P-P-S-R-K-R-P-I-N-T-P-P-N-K-K-P-P-L-P-K-P-P-V-N-K-P-P-H-K-K-P-S-N-K-R-P-P-P-Y-G-N-Q-P-P-P-S-I-H-F


### FUNCTION Binds directly to 26S ribosomal RNA ### SEQUENCE -M-P-P-K-L-D-P-S-Q-I-V-D-V-Y-V-R-V-T-G-G-E-V-G-A-A-S-S-L-A-P-K-I-G-P-L-G-L-A-P-K-K-I-G-E-D-I-A-K-E-T-A-K-E-W-K-G-L-R-V-T-V-K-L-T-V-Q-N-R-Q-A-K-V-T-V-V-P-S-A-A-A-L-V-I-K-A-L-K-E-P-E-R-D-R-K-K-V-K-N-I-K-H-N-G-N-I-S-F-D-D-V-I-E-I-A-K-I-M-R-P-R-S-I-A-K-E-L-S-G-T-V-K-E-I-L-G-T-C-V-S-V-G-C-T-V-D-G-K-D-P-K-D-L-Q-E-E-I-N-S-G-D-I-D-I-P-N-E


### FUNCTION Potential transcription factor that plays a central role during developmental processes ### SEQUENCE -M-S-S-R-G-F-N-I-K-A-R-G-L-C-N-N-N-N-G-G-G-G-T-G-A-K-C-G-R-W-N-P-T-V-E-Q-V-K-L-L-T-D-L-F-K-A-G-L-R-T-P-S-T-D-Q-I-Q-K-I-S-M-E-L-S-F-Y-G-K-I-E-S-K-N-V-F-Y-W-F-Q-N-H-K-A-R-E-R-Q-K-C-R-K-I-S-T-V-K-F-D-H-R-Q-D-T-D-L-S-K-P-R-R-D-N-V-R-R-H-Q-L-P-A-K-G


### FUNCTION Probably acts as a transcriptional activator Binds to the GCC-box pathogenesis-related promoter element May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways ### SEQUENCE -M-D-Y-S-E-N-V-Q-N-K-N-F-T-P-I-S-Q-P-P-N-L-T-R-D-Q-E-H-A-I-M-V-S-T-L-R-Q-V-I-S-N-T-G-G-D-T-S-S-S-H-Y-I-A-A-S-E-A-L-P-P-S-D-A-G-P-C-P-L-C-G-V-T-S-C-Y-G-C-A-F-P-Q-H-E-E-I-K-Q-E-K-K-H-K-G-V-R-K-K-P-S-G-K-W-S-A-E-I-W-D-P-S-T-R-T-R-R-W-L-G-T-F-P-T-A-E-M-A-A-D-A-Y-D-E-A-A-A-A-L-V-E-K-R-S-A-R-R-G-S-K-K-G-E-G-S-I-H-Q-E-V-G-G-G-D-D


### FUNCTION Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs ### SEQUENCE -M-L-N-L-D-F-T-H-K-T-T-Q-A-T-P-R-L-H-A-V-A-T-E-F-L-R-V-S-N-D-V-A-E-L-H-K-L-S-S-K-L-T-S-D-P-Y-L-F-V-E-F-V-K-T-I-R-G-F-L-S-V-Q-T-A-L-G-L-S-G-E-I-D-T-V-F-L-Q-V-I-K-G-W-F-P-D-L-I-T-E-T-F-S-F-L-I-V-V-R-I-I-N-L-F-N-K-R-A-N-S-K-V-Y-P-D-I-L-R-R-I-G-N-N-A-L-Y-L-T-R-N-P-L-R-G-I-C-L-V-E-K-A-I-N-V-R-D-P-D-C-T-V-F-I-A-L-K-L-H-S-H-Y-V-E-L-S-F-E-E-L-G-S-N-I-V-E-K-L-L-S-V-G-E-S-G-I-C-G-V


### FUNCTION Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light ### SEQUENCE -M-E-G-E-T-A-A-K-A-A-A-S-S-S-S-S-P-S-R-Y-E-S-Q-K-R-R-D-W-N-T-F-L-Q-Y-L-R-N-H-K-P-P-L-N-L-S-R-C-S-G-A-H-V-L-E-F-L-K-Y-L-D-Q-F-G-K-T-K-V-H-A-T-A-C-P-F-F-G-Q-P-N-P-P-S-Q-C-T-C-P-L-K-Q-A-W-G-S-L-D-A-L-I-G-R-L-R-A-A-F-E-E-I-G-G-G-L-P-E-S-N-P-F-A-A-K-A-V-R-I-Y-L-K-E-V-R-Q-T-Q-A-K-A-R-G-I-P-Y-D-K-K-K-R-K-R-P-H-T-D-T-A-T-P-I-A-G-D-G-D-D-A-E-G-S-G-G-A-A-L-V-V-T-A-A-T-T-V


### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-A-G-R-L-S-G-V-A-S-R-I-M-G-G-N-G-V-V-A-R-S-V-G-S-S-L-R-Q-R-A-G-M-G-L-P-V-G-K-H-I-V-P-D-K-P-L-S-V-N-D-E-L-M-W-D-N-G-T-A-F-P-E-P-C-I-D-R-I-A-D-T-V-G-K-Y-E-A-L-A-W-L-S-G-G-L-G-F-F-V-G-L-G-L-L-A-V-L-N-D-K-A-S-K-V-P-F-T-P-R-V-Y-P-Y-D-N-L-R-V-E-L-G-G-E-P