### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-K-H-R-I-K-K-N-D-E-F-Q-T-V-F-Q-K-G-K-S-N-A-N-R-Q-F-V-V-Y-Q-L-D-K-E-E-Q-P-N-F-R-I-G-L-S-V-S-K-K-I-G-N-A-V-V-R-N-R-I-K-R-M-I-R-Q-S-I-T-E-L-K-D-E-I-D-S-G-K-D-F-V-I-I-A-R-K-P-C-A-E-M-T-Y-E-E-L-K-K-S-L-I-H-V-F-K-R-S-G-M-K-R-I-K-S-S-V-R-K


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-K-Y-E-I-M-Y-I-I-R-P-G-V-E-E-E-A-Q-K-A-L-V-E-R-F-A-G-V-L-T-N-N-G-A-E-I-I-N-T-K-E-W-G-K-R-R-L-A-Y-E-I-N-D-L-R-E-G-F-Y-M-I-L-N-V-N-A-N-A-E-A-I-N-E-F-D-R-L-A-K-I-N-E-D-I-L-R-H-I-V-V-K-E-E-E-K


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-N-R-V-I-L-V-G-R-L-T-K-D-P-D-L-R-Y-T-P-N-G-V-A-V-A-T-F-T-L-A-V-N-R-A-F-A-N-Q-Q-G-E-R-E-A-D-F-I-N-C-V-I-W-R-K-Q-A-E-N-V-A-N-Y-L-K-K-G-S-L-A-G-V-D-G-R-L-Q-T-R-N-Y-E-G-Q-D-G-K-R-V-Y-V-T-E-V-L-A-E-S-V-Q-F-L-E-P-R-N-G-G-G-E-Q-R-G-S-F-N-Q-Q-P-S-G-A-G-F-G-N-Q-S-S-N-P-F-G-Q-S-S-N-S-G-N-Q-G-N-Q-G-N-S-G-F-T-K-N-D-D-P-F-S-N-V-G-Q-P-I-D-I-S-D-D-D-L-P-F


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-G-R-K-G-G-R-A-K-R-R-K-V-C-F-F-T-S-N-G-I-T-R-I-D-Y-K-D-V-D-L-L-K-R-F-V-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-Y-Q-R-K-L-T-V-A-I-K-R-A-R-Q-M-A-L-L-P-Y-V-G-E


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-K-D-V-K-G-K-G-K-K-G-E-V-K-N-V-P-D-G-Y-A-N-N-F-L-L-K-Q-G-L-A-A-E-A-T-N-S-S-M-K-T-L-E-A-Q-K-R-K-E-E-K-D-A-A-A-E-L-E-S-A-K-Q-L-K-E-T-L-E-K-L-T-V-E-L-K-A-K-S-G-E-G-G-R-L-F-G-S-I-T-S-K-Q-I-V-D-A-M-Q-K-S-H-K-I-K-L-D-K-R-K-F-E-M-D-D-A-I-R-A-L-G-Y-T-N-V-T-V-K-L-H-P-Q-V-T-A-T-V-K-V-H-V-S-E-Q


### FUNCTION Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA The LrgAB and CidA proteins may affect the proton motive force of the membrane May be involved in programmed cell death , possibly triggering PCD in response to antibiotics and environmental stresses ### SEQUENCE -M-S-T-K-K-V-Y-S-F-L-S-Q-A-F-I-F-S-A-I-M-L-I-S-N-I-I-A-T-H-L-P-I-P-M-P-S-S-V-I-G-L-V-I-L-F-S-L-L-C-L-K-V-I-K-L-E-Q-V-E-S-L-G-T-A-L-T-G-I-I-G-F-L-F-V-P-S-G-I-S-V-I-N-S-L-G-V-M-G-Q-Y-F-V-Q-I-L-T-V-I-V-V-A-T-V-I-L-L-A-V-T-G-L-F-A-Q-F-I-L-G-K-D-E-K-E-T-E-D-T-K-E-L-K-V-V-N-K-G-R-K-H-G-K-V-A


### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-D-F-K-Q-Y-S-P-E-E-L-K-E-C-S-M-I-E-V-V-H-S-V-L-G-D-K-R-Q-A-T-T-F-N-E-L-V-Q-E-I-A-Q-V-L-G-L-S-Q-E-Q-V-N-A-K-I-A-Q-F-Y-T-D-L-N-I-D-G-R-F-I-N-L-G-E-N-R-W-G-L-R-S-W-Y-P-Y-E-Q-I-D-E-E-I-L-P-Q-P-K-P-K-K-K-R-K-V-E-D-D-G-F-D-D-Y-I-E-E-D-E-D-F-D-D-A-D-V-T-E-D-E-D-D-D-V-E-D-L-D-K-V-L-E-D-E-D-G-D-D-D-D-L-D-D-L-D-E-D-E-D-D-F-A-E-E-E-L-E-Y-D-E-T-E-E-E-E-E-E-L


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-T-F-E-Q-L-I-P-L-I-I-M-A-F-A-L-G-M-D-A-F-S-V-S-L-G-M-G-M-M-A-L-K-I-R-Q-I-L-Y-I-G-V-T-I-G-I-F-H-I-I-M-P-F-I-G-M-V-L-G-R-F-L-S-E-Q-Y-G-D-I-A-H-F-A-G-A-I-L-L-I-G-L-G-F-Y-I-V-Y-S-S-I-L-E-N-E-E-T-R-T-A-P-I-G-I-S-L-F-V-F-A-F-G-V-S-I-D-S-F-S-V-G-L-S-L-G-I-Y-G-A-Q-T-I-I-T-I-L-L-F-G-F-V-S-M-L-L-A-W-I-G-L-L-I-G-R-H-A-K-G-M-L-G-T-Y-G-E-I-V-G-G-I-I-L-V-G-F-G-L-Y-L-L-F-P-I


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-P-T-L-L-L-G-A-A-I-P-F-G-T-I-A-Y-T-L-F-I-F-L-L-L-L-V-M-L-R-K-F-A-W-G-P-L-M-G-I-M-K-E-R-E-E-H-V-A-N-E-I-D-A-A-E-R-N-N-A-E-A-K-K-L-V-E-E-Q-R-E-M-L-K-Q-S-R-V-E-A-Q-E-L-I-E-R-A-K-K-Q-A-V-D-Q-K-D-V-I-V-A-A-A-K-E-E-A-E-S-I-K-A-S-A-V-Q-E-I-Q-R-E-K-E-Q-A-I-A-A-L-Q-E-Q-V-A-S-L-S-V-Q-I-A-S-K-V-I-E-K-E-L-K-E-E-D-Q-V-K-L-I-R-D-Y-I-K-E-V-G-E-A-R


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-N-G-I-V-A-K-R-Y-A-V-A-L-F-K-I-A-K-E-K-H-V-L-E-M-F-E-E-E-L-R-L-V-Q-N-V-Y-E-K-N-G-E-L-H-S-F-L-T-Q-P-N-I-S-K-E-Q-K-K-T-F-L-A-N-V-F-G-S-V-S-E-S-I-L-N-T-L-Y-I-L-I-D-N-K-R-I-D-I-L-S-D-I-A-N-E-Y-V-V-L-A-N-E-E-R-N-V-A-D-A-T-V-Y-S-T-R-L-L-S-E-E-E-K-L-N-I-A-E-A-F-A-K-R-T-G-K-D-A-I-R-V-K-N-V-V-D-E-D-L-L-G-G-I-K-V-R-I-G-N-R-I-Y-D-G-S-L-Q-G-K-L-A-R-I-Q-R-E-L-M-K-N-R


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-K-T-F-P-V-S-I-V-T-P-D-G-P-V-Y-E-K-E-V-E-M-V-S-V-K-A-E-S-G-E-M-G-I-L-P-G-H-I-P-T-V-A-P-L-K-I-S-A-V-R-L-K-N-G-G-H-T-D-Y-V-A-V-S-G-G-F-I-E-V-R-P-D-K-V-T-V-L-S-S-S-A-E-E-A-N-H-I-D-I-H-R-A-N-E-A-K-R-R-A-E-Q-R-M-Q-D-K-Q-A-H-V-D-F-K-R-A-E-M-A-L-Q-R-A-V-N-R-L-N-V-S-D-M-K


### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-S-V-E-S-F-E-L-D-H-T-I-V-K-A-P-Y-V-R-H-C-G-V-H-N-V-G-S-D-G-I-V-N-K-F-D-I-R-F-C-Q-P-N-K-Q-A-M-K-P-D-V-I-H-T-L-E-H-L-L-A-F-N-L-R-K-Y-I-D-R-Y-P-H-F-D-I-I-D-I-S-P-M-G-C-Q-T-G-Y-Y-L-V-V-S-G-T-P-T-V-R-E-I-I-D-L-L-E-L-T-L-K-D-A-V-Q-I-T-E-I-P-A-A-N-E-T-Q-C-G-Q-A-K-L-H-D-L-E-G-A-K-R-L-M-N-F-W-L-S-Q-D-K-D-E-L-E-K-V-F-G


### FUNCTION May be involved in the biosynthesis of molybdopterin ### SEQUENCE -M-S-V-T-E-H-K-K-Q-A-P-K-E-V-R-C-K-I-V-T-I-S-D-T-R-T-E-E-T-D-K-S-G-Q-L-L-H-E-L-L-K-E-A-G-H-T-V-T-S-Y-E-I-V-K-D-D-K-E-S-I-Q-Q-A-V-L-A-G-Y-H-R-E-D-V-D-V-V-L-T-N-G-G-T-G-I-T-K-R-D-V-T-I-E-A-V-S-A-L-L-H-K-E-I-V-G-F-G-E-L-F-R-M-I-S-Y-L-E-D-I-G-S-S-A-M-L-S-R-A-I-G-G-T-I-G-R-K-V-V-F-S-M-P-G-S-S-G-A-V-R-L-A-M-N-K-L-I-L-P-E-L-G-H-I-T-F-E-L-H-R-Q


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-W-N-E-F-K-K-F-A-F-K-G-N-V-I-D-L-A-V-G-V-V-I-G-A-A-F-G-K-I-V-S-S-L-V-K-D-I-I-T-P-L-L-G-M-V-L-G-G-V-D-F-T-D-L-K-I-T-F-G-K-S-S-I-M-Y-G-N-F-I-Q-T-I-F-D-F-L-I-I-A-A-A-I-F-M-F-V-K-V-F-N-K-L-T-S-K-R-E-E-E-K-E-E-E-I-P-E-P-T-K-E-E-E-L-L-G-E-I-R-D-L-L-K-Q-Q-N-S-S-K-D-R-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-R-Y-T-G-P-A-W-K-L-S-R-R-L-G-I-S-L-S-G-T-G-K-E-L-E-K-R-P-Y-A-P-G-P-H-G-P-N-Q-R-K-K-L-S-E-Y-G-L-Q-L-Q-E-K-Q-K-L-R-H-M-Y-G-M-T-E-R-Q-F-R-R-T-F-D-Q-A-G-K-M-P-G-K-H-G-E-N-F-M-I-L-L-E-A-R-L-D-N-L-V-Y-R-M-G-L-A-R-T-R-R-A-A-R-Q-L-V-N-H-G-H-I-M-V-D-G-A-R-V-D-I-P-S-Y-R-V-K-P-G-Q-T-I-S-V-R-E-K-S-N-N-L-V-V-V-K-E-A-I-E-V-N-N-F-V-P-E-Y-L-T-F-D-A-D-K-L-E-A-T-Y-T-R-H-A-E-R-A-E-L-P-A-E-I-N-E-A-L-I-V-E-F-Y-S-R


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-S-C-S-H-N-G-T-R-V-L-D-S-R-P-V-D-E-G-R-S-I-R-R-R-R-E-C-E-S-C-L-S-R-F-T-T-F-E-R-V-E-E-S-P-L-I-V-V-K-K-E-G-T-R-E-E-F-N-K-E-K-I-L-R-G-L-I-K-A-C-E-K-R-P-V-S-L-R-Q-L-E-E-V-T-Q-S-V-E-R-E-L-R-N-L-G-I-S-E-V-K-S-D-M-I-G-E-I-V-M-E-E-L-R-D-I-D-D-V-A-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-L-N-V-F-I-E-E-L-K-D-I-L-Q-K-E-R-E


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-M-I-N-E-Q-I-R-A-R-E-V-R-L-V-G-A-N-G-D-Q-L-G-I-K-S-R-N-D-A-L-D-L-A-A-N-L-N-L-D-L-V-L-V-A-P-N-A-K-P-P-V-C-R-I-M-D-Y-G-K-F-R-F-E-Q-Q-K-K-E-K-E-Q-R-K-N-Q-K-V-I-S-M-K-E-V-R-L-S-P-T-I-D-E-H-D-F-N-T-K-L-R-N-A-I-K-F-L-E-K-G-D-K-V-K-A-S-I-R-F-K-G-R-A-I-T-H-K-E-I-G-Q-R-V-L-D-R-F-S-E-A-C-A-E-V-S-T-I-E-S-K-P-K-M-E-G-R-S-M-F-L-V-L-A-P-K-N-D-K


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-G-G-T-V-T-R-Q-R-R-K-K-V-I-K-L-A-K-G-Y-Y-G-S-K-N-T-L-F-K-V-A-N-Q-Q-V-M-K-S-L-M-Y-A-F-R-D-R-R-Q-K-K-R-D-F-R-K-L-W-I-T-R-I-N-A-A-A-R-M-N-G-L-S-Y-S-R-L-M-H-G-L-K-N-A-G-I-E-V-N-R-K-M-L-A-D-L-A-V-H-D-E-K-A-F-A-E-L-A-T-V-A-K-N-N-I-N


### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-S-Q-Q-K-G-K-K-S-R-I-N-V-E-I-Y-G-Q-Q-Y-S-V-V-G-D-E-S-T-S-H-I-R-M-V-A-A-I-V-D-D-K-M-R-E-L-N-A-K-N-P-S-L-D-T-S-R-L-A-V-L-T-A-V-N-V-I-H-D-Y-I-K-L-K-E-E-H-E-K-L-K-E-S-M-T-K-K-G-M-E


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-K-V-T-K-A-D-I-V-I-S-A-V-K-P-E-Q-Y-P-D-G-D-L-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-K-I-L-N-R-K-K-L-V-R-I-S-S-K-P-G-K-T-Q-T-L-N-F-F-L-I-N-E-M-M-H-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-T-E-R-A-A-W-G-K-M-I-E-T-Y-F-T-T-R-E-Q-L-D-A-A-V-L-V-V-D-L-R-H-K-P-T-N-D-D-V-M-M-Y-D-F-L-K-H-Y-D-I-P-T-I-I-I-A-T-K-A-D-K-I-P-K-G-K-W-Q-K-H-L-K-V-V-K-E-T-L-D-I-E-S-G-D-E-V-V-L-F-S-S-E-T-G-L-G-K-E-E-A-W-K-A-I-H-K-F-T-K-T-K-N-A


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-E-T-G-G-K-Q-I-K-V-E-A-G-Q-A-I-Y-I-E-K-L-D-V-E-A-G-E-T-V-T-F-D-K-V-L-F-V-G-G-E-N-V-K-V-G-S-P-V-V-E-G-A-T-V-T-A-K-V-E-K-Q-G-R-A-K-K-I-I-V-F-K-Y-K-A-K-K-N-N-R-K-K-Q-G-H-R-Q-P-Y-T-K-L-V-V-E-A-I-N-A


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-F-K-Q-H-I-A-I-V-P-D-Y-P-K-E-G-I-V-F-K-D-I-T-P-L-M-N-D-G-K-A-Y-K-A-A-T-D-A-I-V-E-Y-A-K-E-R-D-I-D-L-V-V-G-P-E-A-R-G-F-I-I-G-C-P-V-S-Y-A-L-E-V-G-F-A-P-V-R-K-L-G-K-L-P-R-E-V-I-T-V-D-Y-G-K-E-Y-G-K-D-V-L-T-I-H-K-D-A-I-K-P-G-Q-R-V-L-I-T-D-D-L-L-A-T-G-G-T-I-E-A-T-I-K-L-V-E-E-L-G-G-V-V-A-G-I-A-F-L-V-E-L-T-Y-L-D-G-R-K-M-L-D-G-Y-D-V-L-V-L-E-K-Y


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-L-G-L-D-V-G-T-K-T-V-G-V-A-I-S-D-E-M-G-W-T-A-Q-G-L-E-T-I-K-I-N-E-E-R-G-Q-F-G-F-D-R-I-S-E-L-V-K-Q-Y-D-V-D-K-I-V-V-G-L-P-K-N-M-N-G-T-I-G-P-R-G-E-A-C-Q-Q-F-A-E-N-L-R-E-L-L-Q-L-D-V-V-M-W-D-E-R-L-S-T-M-A-A-E-R-L-L-I-S-A-D-V-S-R-K-K-R-K-Q-V-I-D-K-M-A-A-V-V-I-L-Q-G-F-L-D-S-K


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-T-E-K-T-Y-P-M-T-Q-E-G-K-Q-K-L-E-N-E-L-E-D-L-K-T-V-K-R-K-E-V-V-E-R-I-K-I-A-R-S-F-G-D-L-S-E-N-S-E-Y-D-A-A-K-D-E-Q-A-F-V-E-G-R-I-T-Q-L-E-N-M-I-R-N-A-V-I-I-T-D-N-G-E-E-S-T-V-V-T-L-G-K-T-V-T-F-K-E-L-P-N-G-D-E-E-A-Y-T-I-V-G-S-A-E-A-D-P-F-E-G-R-I-S-N-D-S-P-I-A-K-S-L-L-G-K-Q-I-G-E-K-V-A-I-Q-T-P-G-G-E-M-Q-V-E-I-I-S-V-K


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-A-K-L-S-E-E-R-R-A-H-N-A-S-I-K-S-D-M-R-S-A-V-K-T-V-E-A-L-V-T-N-N-D-L-E-N-A-K-E-A-F-K-T-A-S-K-K-L-D-K-A-A-R-K-G-L-I-H-Q-N-A-A-A-R-Q-K-S-R-L-A-K-Q-V-N-A


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-E-E-R-N-E-Q-V-V-E-E-V-K-E-A-Q-V-E-E-A-V-T-P-E-N-S-E-E-T-V-E-E-K-S-E-A-A-L-L-Q-E-K-V-D-E-L-Q-A-K-L-T-E-T-E-G-R-T-L-R-L-Q-A-D-F-E-N-Y-K-R-R-V-Q-M-D-K-Q-A-A-E-K-Y-R-A-Q-S-L-V-S-D-I-L-P-A-L-D-N-F-E-R-A-M-Q-V-E-A-T-D-E-Q-T-K-S-L-L-Q-G-M-E-M-V-H-R-Q-L-L-E-A-L-N-K-E-G-V-E-V-I-E-A-V-G-K-Q-F-D-P-N-E-H-Q-A-I-M-Q-V-E-D-S-E-F-E-S-N-A-V-V-E-E-F-Q-K-G-Y-K-L-K-D-R-V-I-R-P-S-M-V-K-V-N-Q


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-L-L-I-D-F-I-D-E-T-E-E-V-K-E-E-Y-V-N-L-I-R-E-I-L-G-K-A-A-Q-M-E-K-I-E-D-G-A-E-L-S-V-T-F-V-D-N-E-R-I-R-E-I-N-R-D-Y-R-D-K-D-Q-P-T-D-V-I-S-F-A-M-E-E-M-G-E-G-E-M-E-I-V-G-V-E-M-P-R-M-L-G-D-L-I-I-S-I-P-R-A-K-E-Q-A-E-E-Y-G-H-S-F-D-R-E-L-G-F-L-A-L-H-G-F-L-H-L-L-G-Y-D-H-M-T-E-E-D-E-K-E-M-F-G-R-Q-K-E-I-L-E-A-F-G-L-G-R


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-K-R-R-T-A-R-E-R-A-M-Q-A-L-Y-Q-M-D-I-T-G-E-L-E-P-K-V-A-V-E-N-T-L-D-E-G-E-E-T-N-E-F-L-E-S-L-V-V-G-F-V-E-N-K-E-V-I-D-E-A-I-R-Q-N-L-K-K-W-K-L-E-R-I-S-I-V-D-R-S-I-L-R-V-A-V-Y-E-M-K-Y-M-E-E-I-P-H-N-V-T-I-N-E-A-I-E-I-A-K-T-F-G-D-E-E-S-R-R-F-I-N-G-V-L-S-N-I-K-D-T-L


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-E-N-K-L-S-F-E-E-A-I-S-Q-L-E-H-L-V-S-K-L-E-Q-G-D-V-P-L-E-E-A-I-S-Y-F-K-E-G-M-E-L-S-K-L-C-D-E-K-L-K-N-V-Q-E-Q-M-A-V-I-L-G-E-D-G-E-L-E-P-F-T-A-L-G-D-E-A


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-G-Q-R-H-I-K-I-R-E-I-I-A-N-K-E-I-E-T-Q-D-E-L-V-D-I-L-R-N-E-G-F-N-V-T-Q-A-T-V-S-R-D-I-K-E-L-H-L-V-K-V-P-L-H-D-G-R-Y-K-Y-S-L-P-A-D-Q-R-F-N-P-L-Q-K-L-K-R-N-L-V-D-S-F-V-K-L-D-T-A-G-H-M-L-V-L-K-T-L-P-G-N-A-H-S-L-G-A-L-I-D-H-L-E-W-D-E-I-I-G-T-I-C-G-D-D-T-C-L-I-I-C-R-T-P-E-D-T-G-V-V-S-D-R-F-L-N-M-L


### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-D-R-T-E-Q-K-S-I-I-E-G-L-L-F-V-S-G-D-E-G-I-Y-P-E-Q-I-A-K-V-L-E-I-E-G-N-E-V-I-D-I-L-E-E-M-Q-K-E-C-E-G-A-H-R-G-L-Q-I-V-Q-Y-A-K-V-Y-R-F-A-T-K-K-E-H-A-S-Y-Y-Q-K-L-I-E-I-P-T-A-A-S-L-S-Q-A-A-L-E-T-L-A-I-V-A-Y-R-Q-P-I-T-R-T-E-M-E-E-I-R-G-V-K-T-D-K-A-L-Q-T-L-V-S-H-L-L-I-K-E-M-G-R-A-E-G-P-G-R-P-I-L-Y-G-T-T-K-E-F-L-D-T-F-G-L-K-T-L-D-D-L-P-P-L-S-E-E-N-E-Q-M-N-E-A-D-L-F-F-G-S-L-Q-E-I-S-K


### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-F-K-V-F-Y-Q-E-K-M-T-E-V-P-V-R-E-N-T-K-V-L-Y-L-E-A-T-S-E-K-D-V-R-T-K-L-N-K-F-A-Y-N-I-E-F-V-Q-S-V-T-G-N-H-L-E-Y-E-K-A-N-A-D-L-T-L-A-E-I-V


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-L-T-M-K-D-V-I-R-E-G-D-P-I-L-R-N-V-A-E-E-V-V-I-P-A-S-E-E-D-T-N-T-L-K-E-M-I-E-F-V-I-N-S-Q-D-P-E-M-A-E-K-Y-S-L-R-P-G-I-G-L-A-A-P-Q-I-G-I-S-K-K-M-I-A-V-H-V-T-D-T-D-G-T-L-Y-S-H-A-L-F-N-P-K-I-I-S-H-S-V-E-R-T-Y-L-Q-S-G-E-G-C-L-S-V-D-R-E-V-P-G-Y-V-P-R-Y-T-R-I-T-V-K-A-T-S-I-N-G-E-E-V-K-L-R-L-K-G-L-P-A-I-V-F-Q-H-E-I-D-H-L-N-G-V-M-F-Y-D-H-I-N-K-E-N-P-F-A-A-P-D-G-S-K-P-L-E-R


### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-V-L-Y-T-T-A-S-C-A-S-C-R-K-A-K-A-W-L-E-E-N-Q-I-D-Y-T-E-K-N-I-V-S-N-S-M-T-V-D-E-L-K-S-I-L-R-L-T-E-E-G-A-T-E-I-I-S-T-R-S-K-T-F-Q-D-L-N-I-N-I-E-E-L-S-L-N-E-F-Y-K-L-I-I-E-H-P-L-M-L-R-R-P-I-M-L-D-E-K-R-L-Q-I-G-F-N-D-E-E-I-R-K-F-L-P-R-S-V-R-T-F-L-N-I-E-L-Q-K-L-A-N


### FUNCTION Catalyzes the reduction of arsenate ### SEQUENCE -M-E-N-K-K-T-I-Y-F-L-C-T-G-N-S-C-R-S-Q-M-A-E-A-W-G-K-Q-Y-L-G-D-K-W-N-V-Y-S-A-G-I-E-A-H-G-V-N-P-N-A-I-K-A-M-N-E-V-N-I-D-I-T-N-Q-T-S-D-I-I-D-A-N-I-L-N-R-A-D-L-V-V-T-L-C-S-H-A-D-A-V-C-P-S-T-P-P-H-V-N-R-V-H-W-G-F-D-D-P-A-G-K-E-W-P-E-F-Q-R-V-R-D-E-I-G-E-R-I-K-R-F-S-E-T-G-E


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-A-I-P-Y-V-V-E-Q-T-K-L-G-E-R-S-Y-D-I-Y-S-R-L-L-K-D-R-I-V-I-I-G-S-E-I-N-D-Q-V-A-S-S-V-V-A-Q-L-L-F-L-E-A-E-D-A-E-K-D-I-F-L-Y-I-N-S-P-G-G-S-T-T-A-G-F-A-I-L-D-T-M-N-L-I-K-P-D-V-Q-T-L-C-M-G-F-A-A-S-F-G-A-L-L-L-L-S-G-A-K-G-K-R-F-A-L-P-N-S-E-I-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-T-E-I-E-I-T-A-K-R-I-L-K-L-K-H-D-I-N-K-M-I-A-E-K-T-G-Q-P-I-E-R-V-A-H-D-T-E-R-D-Y-F-M-T-A-E-E-A-K-A-Y-G-I-V-D-D-V-V-T-K-K


### FUNCTION Possible metal-dependent hydrolase ### SEQUENCE -M-N-D-L-R-Y-P-I-G-Q-F-T-Y-K-R-P-I-T-E-E-M-I-D-T-W-I-Q-E-I-E-D-L-P-N-E-L-T-K-A-I-K-D-L-D-Q-K-Q-L-D-T-P-Y-R-V-G-G-W-T-V-R-Q-V-V-H-H-V-V-D-S-H-M-N-S-Y-I-R-F-K-L-A-L-T-E-K-N-P-T-I-K-P-Y-K-E-E-K-W-A-E-L-P-D-S-K-L-P-V-D-V-S-L-V-M-L-E-S-L-H-K-R-W-V-N-L-L-Y-S-L-E-L-E-D-L-E-K-T-F-N-H-P-D-T-G-E-T-K-L-A-A-A-I-G-L-Y-A-W-H-G-R-H-H-T-A-H-I-T-S-L-R-K-R-L-N-W


### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-L-Y-N-I-N-K-R-L-Y-L-F-E-K-G-R-E-E-M-A-E-V-N-V-K-K-S-S-F-F-K-E-K-K-E-V-P-N-T-D-F-S-L-L-K-G-A-L-I-Q-N-L-D-R-L-E-K-F-V-E-A-I-P-Y-K-Y-I-K-E-G-N-V-K-E-N-A


### FUNCTION Can bind to ATTGG and CCAAT motifs  of single-stranded oligonucleotides ### SEQUENCE -M-T-L-T-G-K-V-K-W-F-N-S-E-K-G-F-G-F-I-E-V-E-G-G-N-D-V-F-V-H-F-S-A-I-T-G-D-G-F-K-S-L-D-E-G-Q-E-V-S-F-E-V-E-D-G-N-R-G-P-Q-A-K-N-V-V-K-L


### FUNCTION Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure ### SEQUENCE -M-E-Y-K-T-P-F-I-A-K-K-L-G-V-S-P-K-A-V-V-R-I-A-Q-Q-L-N-L-T-I-E-K-N-K-Y-G-H-F-I-F-T-Q-D-D-L-D-Q-M-L-E-Y-H-R-S-Q-I-E-Q-S-Q-N-T-H-P-T-Q-K-T-S-S-N-D-V-E-E-L-K-T-Q-V-N-T-I-V-Q-N-I-S-S-H-D-F-E-Q-L-A-A-Q-L-N-T-I-T-R-R-L-D-R-M-E-E-Q-M-Q-D-K-A-N-D-V-V-T-Y-Q-L-L-Q-H-R-R-E-M-E-E-M-L-E-R-I-Q-K-L-E-A-G-L-K-K-E-E-P-I-Y-I-T-P-D-T-K-P-T-Y-E-R-E-K-K-P-K-R-R-K-M-I-F-S-I-F-G-L


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-F-S-N-I-G-F-P-G-L-I-L-I-L-V-A-V-L-I-L-F-G-P-K-K-L-P-E-I-G-K-A-L-G-E-T-L-K-E-F-K-K-S-T-K-E-L-T-D-D-A-F-Q-E-K-E-K-K-E-K-M


### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-I-S-D-K-I-K-L-T-A-K-D-I-L-E-K-E-F-K-T-G-M-R-G-Y-Q-Q-E-E-V-D-K-F-L-D-M-I-I-K-D-Y-E-A-F-H-K-E-F-E-Q-L-K-Q-Q-N-A-R-L-K-R-E-L-E-E-Q-K-L-A-A-T-Q-V-P-Q-Q-P-V-V-Q-T-P-V-A-Q-P-V-Y-N-N-T-N-T-D-I-L-K-R-L-S-N-L-E-K-A-V-F-G-S-K-L-Y-E


### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-K-I-A-L-I-A-H-D-K-K-K-E-D-M-V-S-F-A-Y-A-Y-K-P-I-F-E-Q-H-E-L-F-A-T-G-T-T-G-L-R-I-M-E-A-T-G-L-V-V-T-R-Y-Q-S-G-P-L-G-G-D-Q-E-I-G-A-M-I-A-K-N-D-L-D-M-V-I-F-F-R-D-P-L-T-A-Q-P-H-E-P-D-V-N-A-L-L-R-L-C-D-V-Y-A-I-P-L-A-T-N-M-A-S-A-E-M-L-M-H-A-L-E-R-G-D-L-D-Y-R-K-L-R-K


### FUNCTION Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c ### SEQUENCE -M-K-K-N-R-L-L-F-R-V-I-I-L-L-I-L-S-G-A-V-G-F-T-L-Y-Q-G-F-F-A-D-K-E-K-M-Q-I-G-K-E-A-P-N-F-V-V-T-D-L-E-G-K-K-I-E-L-K-D-L-K-G-K-G-V-F-L-N-F-W-G-T-W-C-K-P-C-E-K-E-M-P-Y-M-N-E-L-Y-P-K-Y-K-E-K-G-V-E-I-I-A-L-D-A-D-E-T-D-I-A-V-K-N-F-V-N-Q-Y-G-L-K-F-P-V-A-I-D-K-G-Q-K-I-I-G-T-Y-G-V-G-P-L-P-T-S-F-L-I-D-K-D-G-K-V-V-E-Q-I-I-G-E-Q-T-K-E-Q-L-E-G-Y-L-K-K-I-T-P


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-P-F-R-I-H-K-G-T-A-A-V-L-M-N-D-N-I-D-T-D-Q-I-I-P-K-Q-Y-L-K-R-I-E-R-T-G-F-G-K-F-L-F-D-E-W-R-Y-D-N-E-R-H-E-N-P-N-F-P-L-N-A-P-D-R-K-G-A-S-I-L-I-T-G-N-N-F-G-C-G-S-S-R-E-H-A-P-W-A-L-A-D-Y-G-F-R-V-I-I-A-G-G-F-A-D-I-F-Y-M-N-C-M-K-N-G-M-L-P-I-V-M-D-K-E-M-R-E-K-L-V-K-T-D-A-R-E-Q-I-E-V-D-L-E-N-E-V-I-T-T-S-T-H-R-F-H-F-T-I-E-K-M-W-K-E-K-L-L-N-G-L-D-E-I-S-I-T-M-Q-Y-E-Q-E-I-K-E-Y-E-R-R-I-A-A-Y


### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid  by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-A-E-F-K-E-Q-V-L-D-I-L-E-E-V-C-E-N-D-I-V-K-E-N-L-D-V-Q-L-F-E-E-G-I-L-D-S-F-A-V-V-S-L-L-V-E-F-Q-E-R-L-D-I-E-V-S-I-S-D-F-D-R-D-E-W-A-T-P-N-M-V-I-K-K-L-E-E-I-R


### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-T-L-Y-S-S-P-S-C-T-S-C-R-K-A-K-L-W-L-E-E-N-H-I-P-Y-T-E-R-N-I-F-S-D-P-L-T-I-E-E-I-K-E-I-L-R-M-T-E-S-G-T-D-E-I-I-S-T-R-S-K-V-F-Q-E-L-N-V-N-L-E-S-L-P-L-Q-D-L-Y-K-M-I-R-D-Y-P-G-I-L-R-R-P-I-M-I-D-E-K-R-L-Q-V-G-Y-N-E-D-E-I-R-R-F-L-P-R-T-V-R-T-F-Q-L-R-E-A-Q-R-L-V-N


### FUNCTION Can bind to ATTGG and CCAAT motifs  of single-stranded oligonucleotides ### SEQUENCE -M-A-V-T-G-Q-V-K-W-F-N-N-E-K-G-F-G-F-I-E-V-P-G-E-N-D-V-F-V-H-F-S-A-I-E-T-D-G-F-K-S-L-E-E-G-Q-K-V-S-F-E-I-E-E-G-N-R-G-P-Q-A-K-N-V-I-K-L


### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-G-R-E-K-K-Q-E-Y-A-L-F-T-A-W-G-A-S-F-I-A-T-L-G-S-L-Y-F-S-E-I-M-K-F-E-P-C-V-L-C-W-Y-Q-R-I-F-M-Y-P-F-V-L-W-L-G-I-A-V-V-K-K-D-Y-R-I-A-S-Y-S-L-P-I-A-S-I-G-A-C-I-S-L-Y-H-Y-V-I-Q-K-V-A-A-F-S-A-A-G-A-A-C-G-R-V-P-C-T-G-E-Y-I-N-W-F-G-F-V-T-I-P-F-L-A-L-I-G-F-I-T-I-A-V-C-S-F-I-V-I-K-N-K


### FUNCTION Part of the high-affinity ATP-driven potassium transport  system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-A-K-K-Q-S-I-L-S-P-I-I-R-I-T-F-T-F-L-V-L-C-G-L-V-Y-P-L-I-V-T-G-I-A-Q-A-V-M-K-D-N-A-D-G-S-L-I-Y-N-D-K-N-E-V-I-G-S-K-L-I-G-Q-N-F-T-D-P-R-Y-F-H-G-R-V-S-S-I-E-Y-K-A-E-A-S-G-S-N-N-Y-A-P-S-N-P-D-L-E-K-R-V-E-K-S-I-E-E-W-K-K-Q-N-P-S-V-P-V-T-E-V-P-I-D-L-V-T-N-S-G-S-G-L-D-P-D-I-S-P-K-A-A-S-V-Q-V-E-R-I-S-K-L-T-N-I-P-K-E-T-L-D-Q-L-I-K-D-Q-T-E-G-A-A-L-G-L-F-G-E-T-R-V-N-V-L-K-L-N-L-G-L-Q-K-I-M-K


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-I-E-L-V-Q-A-E-E-K-T-A-S-G-I-V-L-P-D-T-A-K-E-K-P-Q-E-G-K-V-I-A-V-G-T-G-R-V-L-E-N-G-E-R-V-A-L-E-V-A-A-G-D-L-I-I-F-S-K-Y-A-G-T-E-V-K-Y-E-G-T-D-Y-L-I-L-R-E-S-D-I-L-A-V-I-G


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-F-M-A-K-A-N-E-V-E-R-K-W-Y-V-V-D-A-E-G-Q-T-L-G-R-L-A-S-E-V-A-S-I-L-R-G-K-N-K-P-T-F-T-P-H-V-D-T-G-D-H-V-I-I-I-N-A-E-K-I-H-L-T-G-N-K-L-N-D-K-I-Y-Y-R-H-T-N-H-P-G-G-L-K-Q-R-T-A-L-E-M-R-T-N-Y-P-V-Q-M-L-E-L-A-I-K-G-M-L-P-K-G-R-L-G-R-Q-V-S-K-K-L-N-V-Y-A-G-A-E-H-P-H-Q-A-Q-K-P-E-V-Y-E-L-R-G


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-R-K-T-N-T-R-K-K-R-V-K-K-N-I-E-A-G-V-A-H-I-R-S-T-F-N-N-T-I-V-T-L-T-D-T-H-G-N-A-L-S-W-S-S-A-G-A-L-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-T-A-A-K-A-A-M-E-H-G-L-K-T-L-E-V-T-V-K-G-P-G-A-G-R-E-A-A-I-R-A-L-Q-A-A-G-L-E-V-T-A-I-R-D-V-T-P-V-P-H-N-G-C-R-P-P-K-R-R-R-V


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-E-V-E-G-T-V-L-E-T-L-P-N-A-M-F-K-V-E-L-E-N-G-H-V-V-L-A-H-V-S-G-K-I-R-M-N-F-I-R-I-L-P-G-D-K-V-T-V-E-L-S-P-Y-D-L-N-R-G-R-I-T-Y-R-F-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-E-G-S-R-K-V-R-N-R-V-G-R-G-I-G-S-G-N-G-K-T-A-G-K-G-H-K-G-Q-N-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-L-P-K-R-G-F-T-N-I-N-R-K-E-F-A-I-V-N-L-S-T-L-N-R-F-E-D-G-T-E-V-T-P-E-L-L-L-E-T-G-V-I-S-K-L-N-D-G-V-K-I-L-A-S-G-A-V-E-K-K-L-T-V-K-A-H-K-F-S-S-S-A-K-E-A-I-E-A-A-G-G-S-V-E-V-I


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-H-R-I-D-P-S-K-L-E-L-E-E-R-V-V-T-I-N-R-V-A-K-V-V-K-G-G-R-R-F-R-F-A-A-L-V-V-V-G-D-K-N-G-H-V-G-F-G-T-G-K-A-Q-E-V-P-D-A-I-R-K-A-I-E-D-A-K-K-N-L-I-A-V-P-L-V-G-T-T-I-P-H-T-I-N-G-H-F-G-A-G-E-V-F-L-K-P-A-A-E-G-T-G-V-I-A-G-G-P-V-R-A-V-L-E-L-A-G-V-Q-D-I-L-S-K-S-L-G-S-N-T-P-I-N-M-I-R-A-T-V-N-G-L-S-E-L-K-R-A-E-D-V-A-K-L-R-G-K-S-V-E-E-L-L-G


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-T-K-A-D-K-N-A-T-R-K-K-R-H-A-R-V-R-A-K-L-T-G-T-A-E-R-P-R-L-N-V-F-R-S-N-Q-H-I-Y-A-Q-V-I-D-D-V-N-G-V-T-L-V-S-A-S-T-L-D-K-D-L-A-L-N-G-T-S-N-I-E-A-A-T-K-V-G-E-S-V-A-K-R-A-V-E-K-G-V-K-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-A-G-L-Q-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-I-L-E-I-P-A-G-V-T-I-T-V-A-E-D-N-T-V-T-V-K-G-P-K-G-E-L-T-R-T-F-N-A-D-M-L-I-K-I-E-E-N-T-L-T-V-E-R-P-S-E-Q-K-E-H-R-A-L-H-G-T-T-R-A-L-I-G-N-M-V-E-G-V-T-E-G-F-A-R-G-L-E-L-V-G-V-G-Y-R-A-Q-K-Q-G-D-K-L-V-L-S-V-G-Y-S-H-P-V-E-M-T-P-E-A-G-L-E-V-E-V-P-A-P-T-K-I-V-I-K-G-I-D-K-Q-R-V-G-E-F-A-A-N-I-R-A-V-R-A-P-E-P-Y-K-G-K-G-I-R-Y-E-G-E-V-V-R-R-K-E-G-K-T-A-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-M-L-T-R-I-R-N-A-N-M-V-R-H-E-K-L-E-V-P-A-S-K-I-K-K-E-I-A-E-L-L-K-R-E-G-F-I-R-D-V-E-Y-I-E-D-N-K-Q-G-I-L-R-I-F-L-K-Y-G-A-N-N-E-R-V-I-T-G-L-K-R-I-S-K-P-G-L-R-V-Y-A-K-A-D-E-V-P-R-V-L-N-G-L-G-I-A-L-V-S-T-S-K-G-V-M-T-D-K-D-A-R-Q-L-Q-T-G-G-E-V-V-A-Y-V-W


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-Q-K-R-T-P-K-F-K-V-Q-E-Y-T-R-C-E-R-C-G-R-P-H-S-V-Y-R-K-F-K-L-C-R-I-C-F-R-E-L-A-Y-K-G-Q-I-P-G-V-K-K-A-S-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-E-K-F-Q-K-E-I-T-P-A-L-V-S-K-F-N-Y-K-S-V-M-Q-V-P-K-I-E-K-I-V-I-N-T-G-V-G-D-A-V-S-N-S-K-T-L-D-N-A-V-E-E-L-T-Q-I-T-G-Q-K-P-V-V-T-R-A-K-K-S-I-A-G-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-Q-M-Y-E-F-F-D-K-L-V-S-V-S-L-P-R-V-R-D-F-R-G-V-S-K-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-D-Y-D-K-V-S-K-V-R-G-M-D-I-V-I-V-T-T-A-K-T-D-E-E-A-R-E-L-L-T-Q-F-G-M-P-F-Q-K


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-H-V-K-K-G-D-K-V-Q-V-I-T-G-K-D-K-G-K-Q-G-V-I-L-V-A-F-P-K-Q-N-R-V-I-V-E-G-V-N-I-V-K-K-H-S-K-P-S-Q-L-N-P-Q-G-G-I-I-T-K-E-A-P-I-H-V-S-N-V-M-I-L-D-P-K-T-G-E-P-T-R-V-G-F-K-V-E-D-G-K-K-V-R-I-A-K-K-S-G-E-L-L-D-K


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-S-G-A-R-E-L-L-T-I-K-V-L-G-G-S-G-R-K-Y-A-N-I-G-D-I-I-V-A-T-V-K-Q-A-T-P-G-G-V-V-K-K-G-D-V-V-K-A-V-V-V-R-T-K-S-G-A-R-R-P-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-K-D-D-K-S-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-S-N-F-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-R-N-Q-R-K-V-Y-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-L-V-E-T-Y-K-T-H-S-L-Y-G-K-R-V-K-Y-S-K-K-Y-K-A-H-D-E-Q-N-Q-A-K-L-G-D-I-V-K-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-I-V-E-E-A-V-I-I


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-Y-R-R-E-H-R-G-K-M-R-G-R-A-K-G-G-T-E-I-A-F-G-E-F-G-L-Q-A-Q-A-A-S-W-I-T-N-R-Q-I-E-A-A-R-R-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-S-K-P-Y-T-A-K-P-L-E-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-V-V-K-P-G-K-I-M-F-E-I-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-A-H-K-L-P-V-K-C-K-F-V-K-R-E-E-N-G-G-E-S-N-E-N


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-Q-A-K-A-V-A-R-T-V-R-I-A-P-R-K-V-R-L-V-V-D-L-I-R-G-K-Q-V-G-E-A-I-A-I-L-N-H-T-P-K-T-A-S-P-V-V-E-K-V-L-K-S-A-I-A-N-A-E-H-N-Y-E-M-D-I-N-S-L-V-V-E-K-V-F-V-D-E-G-P-T-L-K-R-F-R-P-R-A-M-G-R-A-S-Q-I-N-K-R-T-S-H-I-T-V-V-V-S-E-K-K-E-G


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-V-D-D-H-L-M-S-K-I-A-K-L-N-E-T-E-Q-K-Q-V-V-K-T-W-S-R-R-S-T-I-F-P-Q-F-I-G-H-T-I-A-V-Y-D-G-R-K-H-V-P-V-Y-V-T-E-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-K-G-H-D-A-D-D-K-K-T-R-R


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-R-D-P-R-D-I-I-K-R-P-V-I-T-E-R-S-M-E-M-M-A-E-K-K-Y-T-F-D-V-D-V-K-S-N-K-T-E-V-K-D-A-L-E-A-I-F-G-V-K-V-E-K-V-N-I-M-N-Y-K-P-K-A-K-R-V-G-R-H-A-G-F-T-S-R-R-R-K-A-I-V-K-L-T-A-D-S-K-E-I-E-I-F-Q-G-V


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-K-E-K-I-R-I-R-L-K-A-Y-D-H-R-I-L-D-Q-S-A-D-K-I-V-E-T-A-K-R-S-G-A-T-V-S-G-P-I-P-L-P-T-E-K-T-V-Y-T-I-L-R-A-V-H-K-Y-K-D-S-R-E-Q-F-E-M-R-T-H-K-R-L-I-D-I-V-S-P-T-P-Q-T-V-D-S-L-M-R-L-D-L-P-S-G-V-D-I-E-I-K-L


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-A-K-R-D-V-L-P-D-P-M-Y-N-S-K-L-V-T-R-L-I-N-K-M-M-V-D-G-K-K-G-K-S-Q-T-I-L-Y-N-A-F-D-I-V-S-E-R-T-G-K-E-P-M-E-V-F-E-Q-A-L-K-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-N-Y-A-R-L-R-G-E-K-T-M-E-E-R-L-A-N-E-I-L-D-A-A-N-N-A-G-A-S-V-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-N-G-R-T-D-K-V-W-K-S-K-S-P-A-L-N-K-G-F-N-S-L-K-K-K-S-T-D-I-S-A-P-Q-K-R-G-V-C-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-Y-A-R-V-R-L-T-N-G-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-T-A-G-V-D-K-R-M-Q-G-R-S-K-Y-G-T-K-K-P-K-A-A-K-K


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-T-K-E-Q-I-I-E-A-V-K-S-M-T-V-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-V-A-G-G-A-G-E-A-A-A-E-K-T-E-F-D-V-E-L-T-S-A-G-A-Q-K-I-K-V-I-K-V-V-R-E-I-T-G-L-G-L-K-E-A-K-E-L-V-D-N-T-P-K-V-I-K-E-A-A-A-K-E-E-A-E-E-I-K-A-K-L-E-E-V-G-A-A-V-E-V-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-K-V-I-E-T-K-Q-Q-V-V-T-E-I-A-D-K-L-R-A-S-K-S-T-I-V-V-D-Y-R-G-L-T-V-S-E-A-T-E-L-R-K-Q-L-R-E-A-G-V-E-F-K-V-Y-K-N-S-L-T-R-R-A-A-E-S-A-E-M-A-E-L-N-E-F-L-T-G-P-N-A-I-A-F-S-N-E-D-V-V-A-P-A-K-V-L-N-D-F-A-K-D-H-E-A-L-E-I-K-A-G-V-I-E-G-K-L-V-T-L-D-E-V-K-A-I-A-T-L-P-S-R-E-G-L-L-S-M-L-L-S-V-L-Q-A-P-I-R-N-L-A-L-A-T-K-A-V-A-D-Q-K-E-E-Q-G-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-I-K-M-V-K-L-Q-I-P-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-A-G-V-N-I-M-G-F-C-K-E-F-N-A-R-T-A-D-Q-A-G-L-I-I-P-V-E-I-T-V-F-E-D-R-S-F-T-F-I-T-K-T-P-P-A-A-V-L-L-K-K-V-A-G-I-E-S-G-S-G-E-P-N-R-N-K-V-A-T-V-K-R-D-K-V-R-E-I-A-E-T-K-M-P-D-L-N-A-A-S-V-E-A-A-M-R-M-V-E-G-T-A-R-S-M-G-I-V-I-E-D


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-V-G-L-G-N-P-G-R-E-Y-E-L-T-R-H-N-I-G-F-M-A-I-D-E-L-A-K-R-W-N-I-S-L-N-E-Q-K-F-K-G-L-F-G-A-G-F-V-N-G-E-K-V-I-L-L-K-P-L-T-Y-M-N-L-S-G-E-S-I-R-P-L-M-D-Y-Y-K-I-D-V-E-D-F-V-V-L-Y-D-D-L-D-I-P-V-G-K-L-R-L-R-M-K-G-S-A-G-G-H-N-G-V-K-S-T-I-S-H-L-G-T-Q-E-F-Q-R-I-R-M-G-I-D-R-P-K-N-G-M-K-V-V-D-Y-V-L-G-R-F-T-S-E-E-I-P-D-V-N-H-S-I-E-K-A-A-D-A-C-E-E-W-L-N-K-P-F-L-Q-I-M-N-T-F-N-S


### FUNCTION Essential for sporulation Interferes with or is a negative regulator of the pathway leading to asymmetric septation ### SEQUENCE -M-E-V-T-D-V-R-L-R-R-V-N-T-E-G-R-M-R-A-I-A-S-I-T-L-D-H-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-G-T-R-S-K-I-Q-D-A-V-L-T-E-Y-H-R-L-G-E-L-E-E-V-E-F-E-E-A-G-A-S


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-S-K-L-I-D-S-F-M-K-L-P-G-I-G-P-K-T-A-V-R-L-A-F-F-V-L-D-M-K-E-D-D-V-L-G-F-A-K-A-L-V-N-A-K-R-D-L-A-Y-C-S-V-C-G-H-I-T-D-R-D-P-C-Y-I-C-N-D-S-H-R-D-Q-S-V-V-C-V-V-Q-E-P-K-D-V-I-A-M-E-K-M-K-E-Y-Q-G-V-Y-H-V-L-R-G-A-I-S-P-M-G-G-I-G-P-E-D-I-N-I-P-Q-L-L-K-R-L-H-D-E-T-V-Q-E-V-I-L-A-T-N-P-N-I-E-G-E-A-T-A-M-Y-I-S-R-L-L-K-P-T-G-I-K-V-T-R-I-A-H-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-L-E-G-R-R-E-V


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-R-G-G-M-G-N-M-N-N-M-M-K-Q-M-Q-K-M-Q-K-E-M-A-K-A-Q-E-E-L-G-E-K-T-V-E-G-T-A-G-G-G-M-I-T-V-I-A-N-G-H-K-Q-I-L-E-V-K-V-K-E-E-V-V-D-P-E-D-I-E-M-L-Q-D-L-V-L-A-A-T-N-D-A-L-K-K-A-D-E-L-S-N-S-T-M-G-K-F-T-K-G-L-N-L-P-G-G-M-F


### FUNCTION Essential cell division protein ### SEQUENCE -M-S-N-L-A-V-K-Y-K-Q-Q-A-Q-E-E-V-Q-I-Q-T-P-P-Q-Q-M-V-Q-P-K-A-K-A-K-I-T-R-I-E-K-L-L-Y-V-A-F-I-G-F-L-L-Y-A-C-V-A-F-I-G-N-K-A-G-L-Y-Q-V-N-V-E-A-A-T-I-E-Q-K-I-V-Q-Q-Q-K-E-N-Q-E-L-Q-A-E-V-E-K-L-S-R-Y-E-R-I-A-E-V-A-K-K-H-G-L-E-I-N-A-N-N-V-K-G-L-K


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-W-S-K-V-K-Y-F-F-F-D-T-P-E-E-K-E-A-A-Q-Y-S-Y-E-K-E-Q-T-D-M-K-K-Q-Q-D-P-P-E-Q-Q-D-V-T-F-P-K-A-Q-P-K-Q-N-V-V-S-I-E-T-A-K-Q-S-S-K-V-V-L-L-E-P-R-T-Y-S-E-A-Q-G-I-A-D-H-L-K-G-R-R-A-V-V-I-N-L-Q-R-M-S-T-D-Q-A-V-R-I-V-D-F-L-S-G-T-V-Y-A-I-G-G-D-I-Q-K-I-G-P-K-T-F-M-C-T-P-E-N-V-D-I-V-G-A-I-S-E-L-F-G-E-E-D-D-T-N-I-K-R-W


### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide  operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-Q-E-K-A-V-V-L-D-D-Q-M-I-R-R-A-L-T-R-I-S-H-E-I-V-E-R-N-K-G-V-D-N-C-V-L-V-G-I-K-T-R-G-I-F-I-A-Q-R-L-A-E-R-I-G-Q-I-E-G-K-E-M-E-V-G-E-L-D-I-T-L-Y-R-D-D-L-T-L-Q-S-K-N-K-E-P-L-V-K-G-S-D-I-P-V-D-I-T-K-K-K-V-I-L-V-D-D-V-L-Y-T-G-R-T-V-R-A-A-M-D-A-L-M-D-L-G-R-P-S-Q-I-Q-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-S-E-E-R-I-E-V-D-L-Q-E-T-D-Q-Q-D-R-V-S-I-Y-D-K


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-L-N-P-S-I-D-S-L-L-T-K-I-D-S-K-Y-T-L-V-T-V-A-A-K-R-A-R-E-M-Q-L-A-N-N-C-V-V-E-K-P-V-S-H-K-C-V-G-K-A-L-E-E-I-D-M-E-A-L-S-Y-V-P-S-E-D-K-V-T-E


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-V-L-E-I-V-K-H-P-N-E-V-L-E-T-P-C-E-R-V-I-N-F-D-K-K-L-V-K-L-L-K-D-M-H-E-T-M-L-I-A-D-G-V-G-L-A-A-P-Q-V-G-V-S-L-Q-V-A-V-V-D-I-G-D-D-T-G-K-I-E-L-I-N-P-S-I-L-E-K-R-G-E-Q-V-G-P-E-G-C-L-S-F-P-G-L-Y-G-E-V-E-R-A-D-Y-I-K-V-R-A-Q-N-R-R-G-K-V-F-L-L-E-A-E-G-L-L-A-R-A-I-Q-H-E-I-D-H-L-H-G-V-L-F-T-S-K-V-T-R-Y-Y-E-E-N-E-L-E


### FUNCTION Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism ### SEQUENCE -M-K-K-R-R-S-K-K-E-R-Q-E-L-L-Q-Q-T-I-E-T-N-P-F-I-T-D-E-D-L-A-E-K-F-Q-V-S-I-Q-T-V-R-L-D-R-M-E-L-S-I-P-E-L-R-E-R-I-K-H-V-A-T-K-Q-H-E-E-D-V-K-S-L-P-L-E-E-V-V-G-E-I-I-D-I-E-L-D-R-H-A-I-S-I-F-E-V-K-V-E-H-V-F-K-R-N-Q-I-A-R-G-H-H-L-F-A-Q-A-N-S-L-A-V-A-V-I-D-E-E-L-A-L-T-A-K-S-T-I-R-Y-I-R-P-V-K-L-G-E-R-V-V-A-K-A-R-V-E-D-V-E-N-D-K-G-R-T-V-V-K-V-R-S-F-V-G-E-E-L-V-F-T-G-T-F-E-M-Y-R-S-S-N-Y-S-E-E-G-N-N-L


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-D-V-L-E-R-V-T-K-I-I-V-D-R-L-G-V-E-E-T-E-V-V-P-A-A-S-F-K-E-D-L-G-A-D-S-L-D-V-V-E-L-V-M-Q-L-E-D-E-F-E-M-E-I-S-D-E-D-A-E-K-I-A-T-V-G-D-A-V-T-Y-I-E-S-H-L


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-K-W-F-N-V-G-K-I-V-N-T-H-G-V-K-G-E-I-R-V-V-S-R-T-D-F-P-E-E-R-Y-K-V-G-N-T-L-Y-I-S-N-E-K-G-G-E-P-F-P-V-K-I-T-S-H-R-Q-H-K-T-F-D-L-L-T-F-E-G-Y-G-N-V-N-E-V-E-Q-F-K-G-S-L-L-K-V-P-E-D-Q-L-G-E-L-A-E-G-E-Y-Y-Y-H-E-I-I-G-C-N-V-V-T-E-E-G-E-A-L-G-T-I-K-E-V-L-S-P-G-A-N-D-V-W-V-I-K-R-P-K-G-Q-D-L-L-I-P-Y-I-D-D-V-V-L-Q-V-N-I-E-N-K-L-V-T-I-H-V-T-E-G-L-L


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-Q-Q-L-I-A-E-I-T-K-G-Q-L-K-T-D-L-P-S-F-R-P-G-D-T-L-R-V-H-V-K-V-V-E-G-T-R-E-R-I-Q-L-F-E-G-V-V-I-K-R-R-G-G-G-I-S-E-T-F-T-V-R-K-I-S-Y-G-V-G-V-E-R-T-F-P-V-H-T-P-R-I-A-K-I-E-V-L-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-N-L-R-G-K-K-A-R-I-K-E-I-R


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-G-Q-Q-V-L-K-F-S-N-E-K-M-E-K-A-V-A-A-Y-S-R-E-L-A-T-V-R-A-G-R-A-S-A-S-V-L-D-K-V-Q-V-D-Y-Y-G-A-P-T-P-V-V-Q-L-A-N-I-T-V-P-E-A-R-L-L-V-I-Q-P-Y-D-K-T-S-I-G-D-I-E-K-A-I-L-K-A-D-L-G-L-N-P-S-N-D-G-T-V-I-R-I-A-F-P-A-L-T-E-E-R-R-R-D-L-V-K-V-V-K-K-Y-A-E-E-A-K-V-A-V-R-N-V-R-R-D-G-N-D-D-L-K-K-L-E-K-A-G-E-I-T-E-D-D-L-R-G-Y-T-E-D-I-Q-K-E-T-D-K-Y-I-A-K-V-D-E-I-A-K-N-K-E-K-E-I-M-E-V


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-D-K-K-V-T-E-V-V-E-A-F-A-Q-P-I-V-E-E-L-N-L-E-L-V-D-V-E-Y-V-K-E-G-Q-D-W-F-L-R-V-F-I-D-S-E-K-G-V-D-I-E-E-C-G-A-V-S-E-R-L-S-E-A-L-D-K-E-D-P-I-P-H-L-Y-F-L-D-V-S-S-P-G-A-E-R-P-L-K-K-E-K-D-F-Q-Q-A-V-G-K-Q-V-A-I-K-T-Y-E-P-I-D-G-E-K-M-F-E-G-K-M-L-S-Y-D-G-T-T-I-T-L-L-L-T-I-K-T-R-K-K-E-I-Q-I-P-M-D-K-V-A-N-A-R-L-A-V-T-F


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-L-R-A-N-R-V-G-E-Q-M-K-K-E-L-G-D-I-I-S-R-K-I-K-D-P-R-V-G-F-V-T-V-T-D-V-Q-V-S-R-D-L-Q-I-A-T-V-Y-I-S-V-L-G-D-E-E-Q-K-E-N-T-L-K-G-L-A-K-A-K-G-F-I-R-S-E-I-G-Q-R-I-R-L-R-K-T-P-E-I-S-F-E-F-D-E-S-I-G-Y-G-H-R-I-D-T-L-L-H-E-I-N-K-E-G-K-R-E-E


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-Q-E-R-K-N-E-I-I-A-Q-F-R-T-H-E-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-E-Q-I-N-T-L-N-E-H-L-R-T-H-K-K-D-H-H-S-R-R-G-L-L-K-M-V-G-K-R-R-N-L-L-T-Y-L-R-N-S-D-I-T-R-Y-R-E-L-I-T-K-L-G-L-R-R


### FUNCTION Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation Inhibited by the antiholin-like proteins LrgAB In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential ### SEQUENCE -M-K-Y-V-M-L-L-L-Q-V-G-V-L-Y-V-F-S-L-V-G-T-W-I-Q-G-V-F-H-L-S-M-P-G-S-L-I-G-M-L-M-L-F-L-L-L-S-T-R-I-L-P-L-K-W-F-E-E-G-A-E-K-L-L-V-F-L-P-L-F-L-I-P-S-T-T-G-L-M-E-Y-E-S-F-L-F-S-K-G-S-I-I-F-L-L-V-V-I-S-T-V-V-T-L-I-V-S-G-Y-I-S-Q-L-L-V-T-S-K-K


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-K-Q-S-I-N-I-Q-D-Q-F-L-N-Q-L-R-K-E-N-T-F-V-T-L-Y-L-L-N-G-F-Q-L-R-G-L-I-K-G-F-D-N-F-T-V-L-L-E-T-E-G-K-Q-Q-L-I-Y-K-H-A-I-S-T-F-V-P-Q-K-N-V-S-I-E-L-E


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-L-I-P-T-V-I-E-Q-T-N-R-G-E-R-A-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-G-S-A-I-D-D-N-V-A-N-S-I-V-S-Q-L-L-F-L-E-S-Q-D-P-E-K-D-I-H-I-Y-I-N-S-P-G-G-S-I-T-A-G-M-A-I-Y-D-T-M-Q-F-I-K-P-Q-V-S-T-I-C-I-G-M-A-A-S-M-G-A-F-L-L-A-A-G-E-K-G-K-R-Y-A-L-P-N-S-E-A-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-T-E-I-E-I-A-A-K-R-I-L-F-L-R-E-K-L-N-Q-I-L-A-D-R-T-G-Q-P-L-E-V-L-Q-R-D-T-D-R-D-N-F-M-T-A-E-K-A-L-E-Y-G-L-I-D-K-I-F-T-N-R


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-P-K-G-S-G-K-V-I-A-Q-N-K-K-A-F-H-D-Y-F-I-E-E-T-Y-E-A-G-L-V-L-Q-G-T-E-I-K-S-I-R-A-G-R-V-N-L-K-D-A-F-A-R-V-H-N-G-E-V-W-V-H-N-M-H-I-S-T-Y-E-Q-G-N-R-F-N-H-D-P-L-R-T-R-K-L-L-L-H-K-K-E-I-E-K-L-A-G-A-S-K-E-T-G-Y-A-L-V-P-V-R-I-Y-L-K-N-G-F-A-K-M-A-L-G-L-A-K-G-K-K-Q-Y-D-K-R-H-D-L-K-E-K-E-A-K-R-E-I-A-R-A-F-R-D-R-Q-K-M


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-E-A-L-L-V-A-T-G-G-F-F-G-A-I-T-R-F-T-I-S-N-W-F-K-K-R-N-K-T-S-F-P-I-A-T-F-L-I-N-I-T-G-A-F-L-L-G-Y-I-I-G-N-G-V-T-T-G-W-Q-L-L-L-G-T-G-F-M-G-A-F-T-T-F-S-T-F-K-L-E-S-V-Q-L-L-N-R-K-N-F-S-T-F-L-L-Y-L-S-A-T-Y-I-V-G-I-L-F-A-F-L-G-M-K-L-G-G-I


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-R-K-L-I-Y-I-I-V-G-I-A-G-I-L-G-A-L-S-R-Y-Y-L-G-L-T-I-H-E-F-W-H-H-T-F-P-L-A-T-L-L-I-N-L-A-G-C-F-L-L-A-W-L-T-T-Y-I-A-K-L-N-I-L-P-S-D-V-I-T-G-I-G-T-G-F-I-G-S-F-T-T-F-S-T-L-S-V-E-T-I-Q-L-I-N-H-S-E-W-G-I-A-F-L-Y-V-S-C-S-I-L-G-G-L-I-M-S-G-L-G-Y-T-L-G-D-F-L-L-K-K-H-L-T-E-G-D-H-L


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-I-P-N-N-L-R-Y-S-E-E-H-E-W-V-K-T-E-G-N-E-V-V-I-G-I-T-H-F-A-Q-N-E-L-G-D-I-V-F-V-E-L-P-E-V-G-A-T-I-E-A-D-E-P-F-G-S-V-E-S-V-K-T-V-S-E-L-Y-A-P-V-S-G-K-V-V-A-V-N-E-E-L-S-D-Q-P-E-L-V-N-E-S-P-Y-E-G-A-W-M-V-K-V-E-L-S-D-A-S-Q-V-E-K-L-L-T-A-E-K-Y-A-E-M-T-N-Q-D


### FUNCTION Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation Inhibited by the antiholin-like proteins LrgAB In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential ### SEQUENCE -M-K-W-W-K-L-S-G-Q-I-L-L-L-F-C-F-A-W-T-G-E-W-I-A-K-Q-A-H-L-P-I-P-G-S-I-I-G-I-F-L-L-L-I-S-L-K-F-N-L-V-K-K-E-W-I-Q-D-G-A-D-F-L-L-K-E-L-I-L-F-F-I-P-S-A-V-A-V-I-R-Y-K-D-T-L-S-Q-Y-G-I-D-L-I-L-I-I-M-I-S-T-L-C-V-T-L-V-T-G-L-L-T-E-L-L-L-K-R-K-G-S-V-Q


### FUNCTION Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization ### SEQUENCE -M-L-L-Q-G-T-H-R-I-G-R-M-A-M-L-L-A-L-A-D-E-N-E-S-P-V-L-S-I-P-K-G-W-K-Y-C-T-G-K-V-G-S-M-N-S-Q-K-V-V-A-A-M-E-T-A-A-K-S-N-Q-V-I-E-T-D-V-Y-R-E-T-H-A-L-Y-H-A-I-M-E-A-L-Y-G-V-T-R-G-Q-I-Q-L-A-D-V-L-R-T-V-G-L-R-F-A-I-V-R-G-T-P-Y-D-G-K-K-E-G-E-W-V-A-V-A-L-Y-G-T-I-G-A-P-V-K-G-S-E-H-E-A-I-G-L-G-I-N-H-I


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-R-I-S-V-E-N-V-K-H-V-A-H-L-A-R-L-A-I-T-D-Q-E-A-E-K-F-Q-K-Q-L-D-A-I-V-T-F-A-E-Q-L-N-E-L-D-T-T-D-V-K-P-T-T-H-V-L-T-M-K-N-V-M-R-E-D-V-P-E-K-G-L-P-V-E-E-V-L-K-N-A-P-D-H-K-D-N-Q-I-R-V-P-A-V-L-E


### FUNCTION Plays a major role in assembly and budding of virion Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form Inhibits viral transcription and stimulates replication ### SEQUENCE -M-S-L-F-K-R-T-K-K-T-I-L-I-P-P-P-H-L-L-S-G-D-E-D-R-V-T-V-L-N-A-E-G-E-I-K-I-S-G-K-R-P-T-T-L-D-E-K-I-Y-Y-S-M-S-L-A-A-A-I-L-G-G-N-L-H-P-S-F-Q-S-L-T-Y-L-F-Q-Q-E-M-E-F-G-S-T-I-E-K-V-N-F-G-S-R-K-P-A-P-L-T-P-I-R-W-Q-K-P-E-K-C-S-F-R-P-Q-P-L-D-K-K-I-P-P-Q-I-Y-T-V-S-V-E-G-A-T-I-T-F-S-G-R-F-L-F-S-A-S-H-V-G-C-D-D-N-R-V-K-L-A-G-L-D-G-F-I-T-S-P-N-Y-Q-R-V-K-D-Y-Y-A-Q-E-T-V-L-A-L-S-F-E-I-P-T-K-K-G-K


### FUNCTION Plays an essential role for the viral pathogenicity ### SEQUENCE -M-N-S-K-T-P-S-T-D-I-A-A-L-K-D-L-L-R-Y-K-V-T-V-A-R-H-G-F-L-F-D-D-G-K-I-V-W-S-E-D-G-D-E-A-W-N-R-L-L-V-V-V-G-A-L-R-S-S-N-R-M-S-Q-A-L-F-M-D-M-S-I-T-K-G-D-G-Y-L-L-F-S-D-L-Q-G-T-N-N-L-Q-Y-R-T-P-K-F-R-Q-Y-L-F-P-V-D-E-F-L-P-L-P-R


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-E-N-V-N-T-F-L-E-K-V-L-Y-M-E-E-D-R-G-I-A-D-P-P-L-D-S-L-L-S-R-S-G-S-K-Y-G-L-V-I-Y-A-A-K-R-A-R-Q-I-D-Q-Y-Y-I-D-L-H-E-G-S-F-Y-A-H-V-G-P-L-V-S-V-D-A-D-D-K-S-L-T-V-A-M-R-E-I-A-E-D-K-L-D-L-K-S-S-A-A-E


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-E-E-D-R-G-I-A-D-P-P-L-D-S-L-L-S-R-S-G-S-K-Y-G-L-V-I-Y-A-A-K-R-A-R-Q-I-D-Q-Y-Y-I-D-L-H-E-G-S-F-Y-A-H-V-G-P-L-V-S-V-D-A-D-D-K-S-L-T-V-A-M-R-E-I-A-E-D-K-L-D-L-K-S-S-A-A-E


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-Q-T-A-H-I-G-T-D-I-I-E-I-S-R-I-R-K-A-I-K-A-H-S-Q-R-I-L-N-K-I-F-T-K-R-E-Q-E-Y-C-L-S-L-T-N-P-Y-P-S-F-A-A-R-F-A-A-K-E-A-V-A-K-A-L-G-T-G-I-G-K-V-V-R-W-K-D-I-E-I-L-K-S-S-K-H-P-E-V-Y-L-P-E-R-V-Y-K-E-L-G-I-S-K-V-L-L-S-I-S-H-S-R-E-Y-A-T-A-V-A-V-T-L-I


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-M-S-V-A-L-A-V-I-D-Q-V-E-Q-A-A-Q-Q-A-G-D-V-T-A-V-R-S-V-R-L-Q-V-G-E-L-A-G-V-V-P-D-S-L-S-F-C-F-E-L-A-C-A-G-T-V-L-E-G-A-D-L-V-T-E-E-V-P-G-R-A-R-C-A-P-C-A-R-E-W-S-V-G-M-P-P-R-L-S-C-P-E-C-G-G-A-R-V-D-L-L-S-G-R-E-L-Q-I-V-S-V-H-W-E-D-G-R-T-H-A-Q-T-R-E-P-I-S-E-E-R


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-T-T-A-S-S-K-V-A-I-K-P-L-E-D-R-I-V-V-Q-P-L-D-A-E-Q-T-T-A-S-G-L-V-I-P-D-T-A-K-E-K-P-Q-E-G-V-V-L-A-V-G-P-G-R-F-E-D-G-N-R-L-P-L-D-V-T-V-G-D-V-V-L-Y-S-K-Y-G-G-T-E-V-K-Y-N-G-E-E-Y-L-V-L-S-A-R-D-V-L-A-I-V-E-K


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-Y-G-I-G-T-D-L-V-D-P-A-R-I-A-S-S-L-E-R-Y-G-E-Q-F-A-R-R-V-L-A-D-S-E-W-P-D-Y-L-E-H-I-K-P-A-L-F-L-A-K-R-F-A-A-K-E-A-F-S-K-A-T-G-T-G-L-R-A-P-V-M-F-G-N-M-A-V-Q-H-D-S-Q-G-K-P-Y-F-E-F-Q-Q-E-L-A-E-W-I-G-Q-R-G-I-T-R-H-H-L-S-I-S-D-E-L-T-M-V-S-A-F-V-V-L-E-K


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-T-I-Q-M-Q-G-E-V-I-E-T-L-P-N-A-T-F-R-I-K-L-E-N-G-H-I-V-L-G-H-I-S-G-K-M-R-M-N-Y-I-R-I-L-P-G-D-K-V-T-V-D-L-T-P-Y-D-L-T-R-A-R-I-T-F-R-T-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-L-L-N-T-K-Q-M-R-L-R-R-A-K-A-T-R-I-K-I-G-N-S-R-Q-F-R-L-S-V-H-K-S-N-N-H-I-Y-A-Q-I-L-D-P-S-S-N-R-V-I-V-S-A-S-T-V-E-A-E-V-K-K-Q-Y-P-S-G-G-T-I-E-A-A-K-Y-V-G-H-L-V-A-K-K-S-I-E-S-Q-I-Y-E-V-A-F-D-R-S-G-F-K-Y-H-G-R-I-K-A-L-A-D-A-A-R-S-A-G-M-K-F


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-R-L-L-E-Y-Y-R-D-T-V-T-K-E-L-T-Q-K-F-N-Y-K-T-V-M-E-V-P-K-I-T-K-I-T-L-N-M-G-V-G-E-A-S-T-D-K-K-I-I-E-N-A-V-S-D-L-E-K-I-S-A-Q-K-P-V-V-T-K-A-R-K-S-I-A-T-F-K-V-R-Q-G-Y-P-V-G-C-K-V-T-L-R-G-V-K-M-Y-E-F-L-D-R-L-V-N-V-A-I-P-R-I-R-D-F-R-G-I-Q-V-K-G-F-D-G-R-G-N-F-N-M-G-I-K-E-Q-I-I-F-P-E-I-D-Y-D-K-I-D-K-V-R-G-L-N-I-T-V-T-T-T-A-K-T-D-Q-E-A-R-A-L-L-S-A-F-K-F-P-F-K-N


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-K-I-R-K-G-D-S-V-I-V-I-A-G-K-D-K-G-K-Q-S-T-V-I-R-F-Q-S-T-E-R-V-I-V-R-E-V-N-K-V-K-S-H-I-K-P-N-P-N-R-N-I-A-G-G-I-V-E-T-E-K-P-L-H-I-S-N-I-A-I-F-N-P-E-K-N-K-A-D-R-V-G-F-R-F-N-E-S-G-N-K-V-R-Y-F-K-S-D-G-T-L-I-D-S


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-I-A-G-L-L-L-E-K-H-P-P-L-V-L-V-D-V-N-G-I-G-Y-E-I-D-V-P-M-S-T-F-C-R-L-P-G-I-G-E-Q-V-T-L-H-T-H-F-W-V-R-E-D-A-H-L-L-F-G-F-M-T-E-P-E-R-V-L-F-R-Q-L-T-K-I-S-G-I-G-A-R-T-G-L-A-I-L-S-G-L-S-V-N-D-L-H-Q-I-V-V-S-Q-D-S-T-R-L-T-R-I-P-G-I-G-K-K-T-A-E-R-L-L-L-E-L-R-D-K-I-S-P-A-I-T-L-P-E-T-G-T-A-M-A-S-S-T-D-K-D-I-L-N-A-L-S-A-L-G-Y-N-D-R-E-A-N-W-A-V-G-Q-L-S-E-G-V-T-V-S-D-G-I-M-Q-S-L-R-L-L-S-K-A-K


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-G-T-I-F-H-L-D-I-V-S-A-E-E-S-I-Y-S-G-P-A-E-F-I-V-A-P-A-V-M-G-E-V-G-I-F-P-Q-H-T-P-M-L-T-R-I-K-S-G-V-V-R-V-K-A-P-L-Q-D-D-E-E-V-Y-V-S-G-G-M-L-E-V-Q-P-D-V-V-T-I-L-A-D-T-A-V-R-G-K-D-L-D-E-A-K-A-L-E-A-K-R-K-A-E-E-I-M-K-N-K-I-S-E-I-E-Y-A-R-A-Q-A-E-L-I-E-A-T-A-Q-L-A-A-I-Q-K-L-R-K-R-G-H


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-K-G-I-G-I-D-A-V-E-L-S-R-I-K-P-I-V-E-K-Q-G-S-F-I-Q-R-V-L-T-P-N-E-L-T-L-F-E-K-L-S-T-K-R-Q-I-E-F-L-A-G-R-F-A-C-K-E-A-F-S-K-A-W-G-T-G-I-G-K-V-G-L-Q-D-I-E-V-L-T-E-K-T-G-A-P-Y-V-A-N-S-P-H-N-G-K-V-F-V-S-I-T-H-T-E-T-M-A-I-A-Q-I-V-L-E-S-E


### FUNCTION General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases ### SEQUENCE -M-K-T-I-L-P-E-V-L-F-A-A-F-A-T-T-S-A-W-A-A-E-S-V-Q-P-L-E-K-I-A-P-Y-P-Q-A-E-T-G-M-K-R-Q-V-I-Q-L-T-P-Q-E-D-E-S-T-L-K-V-E-L-L-I-G-Q-T-L-E-V-D-C-N-L-H-R-L-G-G-K-L-E-S-K-T-L-E-G-W-G-Y-D-Y-Y-V-F-D-K-V-S-S-P-V-S-T-M-M-A-C-P-D-G-K-K-E-K-K-F-V-T-A-Y-L-G-D-A-G-M-L-R-Y-N-S-K-L-P-I-V-V-Y-T-P-D-N-V-D-V-K-Y-R-V-W-K-A-E-E-K-I-D-N-A-E-V-R


### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-K-I-N-Q-P-A-V-A-G-T-L-E-S-G-D-V-M-I-R-I-A-P-L-D-T-Q-D-I-D-L-Q-I-N-S-S-V-E-K-Q-F-G-D-A-I-R-T-T-I-L-D-V-L-A-R-Y-N-V-R-G-V-Q-L-N-V-D-D-K-G-A-L-D-C-I-L-H-A-R-L-E-A-L-L-A-R-A-S-G-I-P-A-L-P-W-E-D-C-Q


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-P-K-K-T-T-K-K-G-G-P-Q-K-R-P-S-A-E-K-R-I-L-T-A-Q-K-R-Y-L-I-N-Q-S-F-K-S-K-A-K-T-M-M-K-K-F-E-A-A-L-K-A-G-D-Q-S-S-I-T-S-G-L-Q-L-V-Y-S-V-A-D-K-A-V-K-R-G-I-F-K-N-N-K-A-A-R-I-K-S-R-A-T-L-R-A-N-V-K-I


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-T-F-K-G-V-A-S-A-K-D-M-R-V-A-I-V-G-A-C-F-N-G-P-I-A-D-A-L-V-S-G-A-Q-Q-T-F-L-D-L-G-G-A-E-D-M-L-T-V-V-R-V-P-G-S-F-E-I-P-C-T-L-K-K-L-L-T-S-G-V-K-Y-D-A-I-V-A-C-G-V-L-I-K-G-E-T-T-H-Y-D-H-I-A-D-Q-V-S-A-R-I-S-E-L-S-L-E-F-N-L-P-I-T-F-S-V-I-T-A-P-C-I-D-S-A-W-Q-R-A-G-I-K-G-S-N-L-G-I-S-G-M-K-T-A-L-E-M-A-D-L-F-K-K-L


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-R-V-S-T-S-E-F-R-V-G-L-R-I-E-I-D-G-Q-P-Y-L-I-L-Q-N-D-F-V-K-P-G-K-G-Q-A-F-N-R-I-K-V-K-N-F-L-T-G-R-V-I-E-R-T-F-K-S-G-E-S-V-E-T-A-D-V-R-E-Q-Q-M-R-F-L-Y-S-D-Q-E-G-A-T-F-M-D-D-E-T-F-E-Q-E-M-I-F-W-D-K-I-E-N-I-R-Q-W-L-L-E-D-T-I-Y-T-L-V-L-Y-N-G-N-V-I-G-V-E-P-P-I-F-M-E-L-T-I-A-E-T-A-P-G-V-R-G-D-T-A-S-G-R-V-L-K-P-A-V-T-N-T-G-A-K-I-M-V-P-I-F-I-E-E-G-E-V-V-K-I-D-T-R-T-G-S-Y-E-S-R-V-S-K


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-H-R-S-T-L-P-K-Y-A-R-V-L-K-R-K-Q-F-L-Y-I-S-R-A-G-S-H-C-Q-G-S-Q-V-I-F-H-V-A-P-S-R-Y-S-G-C-C-K-L-G-I-T-V-S-K-K-F-G-K-A-H-K-R-N-Y-F-K-R-I-V-R-E-A-F-R-K-K-R-H-S-L-P-A-C-Q-I-V-V-M-P-K-N-K-Q-Q-P-K-F-E-D-L-L-Q-D-F-A-Q-Q-I-P-E-A-L-S-S-K-L-A-K-N-K-P-T-T-G-V-E-Y-S-P-K-N-E-K-C-E-S-V-L-P


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-A-V-A-R-E-N-K-R-R-R-L-V-E-A-N-Y-K-K-R-S-E-L-R-N-I-A-K-S-L-T-A-S-E-E-E-K-E-N-A-R-V-A-L-N-K-M-R-R-D-T-A-H-I-R-L-H-N-R-C-L-L-T-G-R-P-R-G-Y-L-R-K-F-A-I-S-R-I-C-F-R-E-M-A-S-M-G-E-I-P-G-V-I-K-A-S-W


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-E-L-V-V-T-S-R-E-T-D-K-K-S-L-L-K-K-I-R-Q-T-G-G-I-P-A-V-I-Y-S-G-G-K-S-L-A-N-I-V-V-D-A-H-V-F-G-K-F-L-S-S-L-E-S-G-A-L-S-S-T-I-F-S-L-S-Y-E-G-R-T-I-K-A-L-V-K-D-I-Q-Y-Q-V-T-S-Y-R-V-I-H-L-D-F-E-E-L-I-E-D-R-D-V-K-L-N-I-P-I-R-C-I-N-A-V-D-C-V-G-V-K-L-G-G-S-L-R-Q-V-I-R-A-M-R-V-V-C-K-P-K-D-I-V-P-C-L-E-L-D-V-R-S-L-G-L-S-Q-T-R-K-L-A-D-I-N-I-P-A-G-L-R-P-I-T-P-L-K-E-V-V-V-T-V-S-R-R


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-M-L-I-V-A-I-G-N-P-G-R-Q-Y-T-W-T-R-H-N-I-G-F-L-C-A-D-K-L-L-Q-G-F-P-E-A-Q-F-K-E-A-R-K-L-F-S-D-I-A-K-V-E-S-P-Q-G-S-M-V-F-I-K-P-R-T-Y-V-N-L-S-G-K-A-V-S-A-V-K-E-Y-Y-G-I-P-I-D-R-I-L-V-L-A-D-D-V-N-H-P-F-G-N-V-R-L-R-Q-N-A-G-G-G-G-H-K-G-I-K-S-I-T-Q-S-L-G-S-N-D-Y-W-Q-L-R-L-G-I-G-R-P-Q-R-E-D-I-E-L-S-D-F-V-L-G-Q-F-T-E-E-E-Q-I-G-I-Q-S-L-F-I-E-A-S-A-L-F-S-Q-W-C-S-G-T-Q-T-A


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-K-E-K-K-A-Q-L-Y-E-G-A-Y-V-F-S-V-T-L-S-E-E-A-R-R-K-A-L-E-K-V-T-S-G-I-T-N-Y-G-G-E-I-L-K-I-H-D-Q-G-R-K-K-L-A-Y-T-I-R-G-A-R-E-G-Y-Y-Y-L-I-Y-F-T-V-V-P-G-V-I-A-E-L-W-K-E-Y-H-L-N-E-D-L-L-R-F-L-T-L-K-A-D-A-V-K-E-V-L-E-F-A-S-L-P-E


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-N-K-P-V-H-N-N-E-H-R-R-K-R-F-N-K-K-C-P-F-V-S-A-G-W-K-T-I-D-Y-K-D-T-E-T-L-K-K-F-I-T-E-R-G-K-I-L-P-R-R-I-T-G-V-S-S-R-F-Q-G-T-L-T-L-A-I-K-R-A-R-H-I-G-L-L-P-F-V-A-E-D


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-Q-Q-L-L-L-L-E-D-V-D-G-L-G-R-S-G-D-I-V-T-A-R-P-G-Y-V-R-N-Y-L-M-P-Q-K-K-A-V-I-A-G-A-G-T-L-R-L-Q-A-K-L-K-E-E-R-L-L-R-A-A-E-D-R-A-E-S-E-K-L-A-E-A-L-R-D-V-I-L-E-F-Q-V-R-V-D-P-D-N-N-M-Y-G-S-V-T-I-S-D-I-I-D-E-A-A-K-K-N-I-I-L-T-R-K-N-F-P-H-S-H-Y-A-I-K-N-L-G-K-K-S-V-P-L-K-L-K-E-D-V-T-A-T-L-F-V-E-V-S-S-E-S-S-Y-V-A-V-L-N-Q-Q-P-T-Q-E-E-P-A-A-E-E-S-N


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-A-L-N-L-K-I-N-R-Q-I-R-A-P-K-V-R-L-I-G-S-S-G-E-Q-L-G-I-L-N-T-K-D-A-L-D-L-A-R-E-A-D-L-D-L-V-E-V-A-S-N-S-E-P-P-V-C-K-I-M-D-Y-G-K-Y-R-Y-D-L-T-K-K-E-K-D-S-K-K-A-Q-H-Q-V-R-I-K-E-V-K-L-K-P-N-I-D-E-G-D-F-S-T-K-L-K-Q-A-R-A-F-I-E-K-G-N-K-V-K-I-T-C-M-F-R-G-R-E-L-A-Y-P-E-H-G-H-R-V-V-Q-K-M-S-Q-G-L-E-D-I-G-F-M-E-S-E-P-K-L-N-G-R-S-L-I-C-V-M-A-P-G-T-V-K-T-K-K-K-Q-D-K-I-N-A-Q-D-E-K-Q


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-A-T-G-S-V-A-S-R-R-R-R-K-R-V-L-K-Q-A-K-G-F-W-G-D-R-K-G-H-F-R-Q-S-R-S-S-V-M-R-A-M-A-F-N-Y-M-H-R-K-D-R-K-G-D-F-R-S-L-W-I-A-R-L-N-V-A-S-R-I-N-G-L-S-Y-S-R-L-I-N-G-L-K-C-A-G-I-D-L-N-R-K-M-L-S-E-M-A-I-H-N-P-M-G-F-A-E-V-A-N-Q-A-K-K-A-L-E-A-T-I


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-D-K-G-T-K-E-E-I-T-K-K-F-Q-L-H-E-K-D-T-G-S-A-D-V-Q-I-A-I-L-T-E-H-I-T-E-L-K-E-H-L-K-R-S-P-K-D-Q-N-S-R-L-A-L-L-K-L-V-G-Q-R-R-K-L-L-E-Y-L-N-S-T-D-T-E-R-Y-K-N-L-I-T-R-L-N-L-R-K


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-K-E-D-T-I-V-L-E-G-R-V-Q-E-L-L-P-G-M-H-F-K-I-L-L-E-N-G-M-P-V-T-A-H-L-C-G-K-M-R-M-S-N-I-R-L-L-V-G-D-R-V-T-V-E-M-S-A-Y-D-L-T-K-A-R-V-V-Y-R-H-R


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-S-N-K-K-V-I-K-L-I-K-L-Q-I-P-G-G-K-A-N-P-A-P-P-I-G-P-A-L-G-A-A-G-V-N-I-M-G-F-C-K-E-F-N-A-A-T-Q-D-R-P-G-D-L-L-P-V-V-I-T-V-Y-S-D-K-T-F-T-F-I-T-K-Q-P-P-V-S-S-L-I-K-K-A-L-N-L-E-S-G-S-K-I-P-N-R-N-K-V-G-K-L-T-Q-A-Q-V-T-A-I-A-E-Q-K-M-K-D-M-D-V-V-L-L-D-S-A-K-R-M-V-E-G-T-A-R-S-M-G-I-D-V-E


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-K-E-E-K-K-L-L-L-Q-E-V-E-E-K-I-S-A-S-Q-G-F-I-L-L-R-Y-L-G-F-S-A-A-Y-S-R-E-F-R-N-S-L-S-G-V-S-A-E-F-E-V-L-K-K-R-I-F-F-K-A-I-E-N-S-G-F-E-I-D-S-S-D-T-G-G-H-L-G-V-V-F-A-Y-D-D-A-V-S-A-A-K-Q-V-L-D-F-N-K-Q-H-N-D-S-L-V-F-L-A-G-R-I-D-S-A-N-L-S-G-K-E-V-E-A-V-A-K-L-P-S-M-K-E-L-R-Q-Q-V-V-G-L-L-A-A-P-M-S-Q-V-V-G-I-M-G-S-A-L-S-G-V-I-S-C-I-D-Q-K-T-Q-K-N


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-T-T-Q-S-L-E-T-L-V-E-T-L-S-N-L-T-V-L-E-L-A-A-L-K-K-L-L-E-D-K-W-D-V-T-A-A-A-P-M-M-A-V-A-A-G-A-A-V-G-G-D-A-A-P-A-E-S-T-E-F-A-V-I-L-E-D-V-P-A-D-K-K-I-G-V-L-K-V-V-R-E-V-T-G-L-A-L-K-E-A-K-E-M-T-E-G-L-P-K-T-V-K-E-K-T-S-K-S-D-A-E-D-T-V-K-K-L-Q-D-A-G-A-K-A-S-F-K-G-L


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-G-N-L-I-K-E-L-Q-D-E-Q-L-R-K-E-A-L-T-D-F-R-V-G-D-T-I-R-V-A-T-K-I-V-D-G-G-K-E-R-T-Q-V-F-Q-G-T-V-M-A-R-R-G-G-G-A-G-E-T-V-A-L-H-R-V-A-Y-G-E-G-M-E-K-S-F-L-L-H-S-P-K-I-V-G-I-E-V-V-K-R-G-K-V-S-R-A-R-L-Y-Y-L-K-G-K-T-G-K-A-A-K-V-K-E-Y-I-G-P-R-A-P-K


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-N-P-K-N-K-K-E-K-T-F-L-G-I-D-Y-G-Q-R-R-I-G-L-A-Y-A-A-S-P-L-F-I-S-L-P-I-G-C-I-E-A-G-N-T-V-E-A-T-A-K-I-L-F-N-I-I-Q-E-R-S-V-S-C-V-V-L-G-N-P-I-P-M-Q-K-G-Q-K-S-A-L-Q-E-E-I-T-K-L-S-S-L-I-Q-E-S-C-G-V-E-V-I-L-W-D-E-R-L-S-S-A-Q-A-E-R-M-L-K-G-D-C-G-L-S-R-K-K-R-K-G-K-T-D-T-I-A-A-T-L-I-L-T-S-F-L-E-S-S-P-P-K-I-F-L-K-K-T-C-P-K-P-P-V-R


### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-I-R-F-L-R-N-N-A-L-Y-F-A-W-L-I-C-S-T-G-T-V-M-S-I-Y-Y-S-Y-L-L-N-I-E-P-C-V-L-C-Y-Y-Q-R-I-C-L-F-P-L-S-I-I-L-G-I-A-T-Y-R-E-D-N-L-V-K-I-Y-A-L-P-L-S-I-T-G-M-V-I-A-V-Y-Q-I-C-L-Q-E-I-S-G-M-T-I-D-I-C-G-R-V-S-C-S-T-K-L-F-V-F-G-F-I-T-V-P-M-A-S-A-L-A-F-C-A-I-S-C-L-L-I-L-S-G-S-K-K-K


### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-A-Q-E-S-N-E-N-G-W-G-D-F-L-E-L-C-S-K-I-K-T-P-E-A-F-H-D-F-F-A-L-F-L-T-F-G-E-R-E-S-M-A-S-R-F-L-I-V-Q-A-L-L-A-E-Q-L-T-Q-R-E-I-A-Q-K-Y-G-V-S-I-A-Q-I-T-R-G-S-N-A-L-K-A-I-D-P-K-F-K-E-F-L-K-N-L-N-R-K-Y-G-N-Q


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-L-S-S-Q-L-S-V-G-M-F-I-S-T-K-D-G-L-Y-K-V-V-A-V-S-K-V-T-G-N-K-G-E-S-F-I-K-A-S-L-K-A-A-D-S-D-V-I-V-E-R-N-F-K-I-G-Q-E-I-K-E-A-Q-F-E-S-R-N-L-E-Y-L-Y-I-E-D-E-N-F-L-F-L-D-L-G-N-Y-E-K-I-Y-I-S-K-E-I-M-K-D-N-F-L-F-L-K-A-G-V-T-V-S-A-M-V-Y-D-D-V-V-F-S-I-E-L-P-H-F-L-E-L-M-V-S-K-T-D-F-P-G-D-S-L-L-I-T-G-G-T-K-K-A-L-L-E-T-G-V-E-I-T-V-P-P-F-V-E-I-G-D-I-I-K-I-D-T-R-T-C-E-Y-I-Q-R-V


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-K-N-V-A-L-D-K-A-L-K-E-I-L-N-E-E-G-A-S-T-Q-E-E-I-C-E-K-L-S-S-L-G-I-A-T-T-Q-S-S-V-S-R-W-L-K-K-V-H-A-I-K-I-P-G-D-K-G-A-R-Y-S-L-P-P-S-I-D-D-S-S-I-K-H-L-V-F-S-I-R-H-N-S-S-L-I-V-I-R-T-A-P-G-S-A-S-W-I-A-S-L-I-D-N-K-F-A-E-S-I-L-G-T-L-A-G-D-D-T-I-F-I-T-P-I-T-E-S-T-I-S-L-T-A-K-D-I-E-N-F-L-L-V-F-S-E


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-E-K-R-K-D-T-K-T-T-I-A-K-A-S-D-A-Q-N-K-S-W-Y-V-I-D-A-T-G-K-T-L-G-R-L-S-S-E-V-A-K-I-L-R-G-K-H-K-V-T-Y-T-P-H-I-A-M-G-D-G-V-I-V-I-N-A-E-K-V-H-L-T-G-A-K-K-G-Q-K-I-Y-R-Y-Y-T-G-Y-I-S-G-M-R-E-I-P-F-E-N-M-L-A-K-K-P-S-Y-I-I-E-H-A-I-K-G-M-M-P-K-T-R-L-G-K-R-Q-L-K-S-L-R-I-L-K-G-D-C-Y-K-T-F-E-A-Q-K-P-I-L-L-D-V


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-L-E-D-D-V-K-S-I-I-V-E-Q-L-G-V-D-A-S-E-V-N-E-N-S-S-F-I-E-D-L-N-A-D-S-L-D-L-T-E-L-I-M-T-L-E-E-K-F-N-F-E-I-S-E-Q-D-A-E-Q-L-R-T-V-G-D-V-I-T-Y-I-K-T-R-Q-G


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-L-K-Y-P-D-Y-L-S-K-L-I-S-L-L-R-K-L-P-G-I-G-F-K-T-A-E-K-L-A-F-E-L-L-D-W-D-Q-D-Q-L-E-A-M-G-Q-A-F-S-E-V-S-A-A-R-S-H-C-S-T-C-F-C-L-K-N-L-P-E-S-N-C-E-F-C-Q-N-N-R-D-T-S-T-L-C-I-V-A-T-P-K-D-I-F-S-L-E-R-S-Q-I-F-K-G-H-Y-Y-V-L-G-T-L-L-S-P-I-T-G-K-H-I-D-V-E-R-I-G-L-L-K-Q-R-I-E-F-L-K-P-Q-E-I-I-L-A-L-D-A-T-L-E-G-D-A-T-A-L-F-L-K-Q-E-L-A-F-S-S-A-S-I-S-R-L-A-L-G-L-P-I-G-L-S-F-D-Y-V-D-S-G-T-L-A-R-A-F-S-G-R-N-P-Y


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-T-E-N-R-R-I-K-K-V-N-S-L-L-R-E-A-I-A-N-V-I-L-K-D-V-K-H-P-K-I-S-N-Q-W-I-T-V-T-R-V-C-L-S-K-D-L-H-S-A-R-V-Y-V-S-I-M-P-H-E-N-T-S-A-E-T-L-D-A-L-K-A-S-A-G-F-I-A-Y-K-A-S-K-G-V-V-L-K-Y-F-P-E-I-H-F-Y-I-E-D-I-F-S-P-Q-D-H-I-E-N-L-L-W-K-I-R-E-Q-D-K-N


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-S-K-E-I-V-S-N-R-K-A-L-R-N-Y-E-V-L-D-T-L-E-A-G-V-V-L-T-G-T-E-I-K-S-L-R-D-H-G-G-N-L-G-D-A-Y-V-A-I-S-K-G-E-A-W-L-L-N-A-S-I-A-P-Y-R-F-G-N-I-Y-N-H-E-E-R-R-K-R-K-L-L-L-H-R-Y-E-I-R-K-L-E-G-R-V-A-Q-K-G-I-T-I-I-P-L-G-M-F-L-S-R-G-Y-V-K-I-R-L-G-C-C-R-G-K-K-A-H-D-K-R-Q-T-I-I-A-R-E-K-Q-R-E-V-E-S-A-M-K-R-Y-R


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-I-V-C-E-L-E-S-G-A-D-L-P-E-Y-A-T-E-G-A-S-G-A-D-L-R-A-H-I-E-E-P-I-A-V-L-P-G-Q-R-V-L-I-P-T-G-I-K-M-Q-I-P-Q-G-Y-E-V-Q-V-R-P-R-S-G-L-A-L-K-H-G-I-M-V-V-N-S-P-G-T-I-D-A-D-Y-R-G-E-V-C-I-I-L-A-N-F-G-E-S-T-F-I-I-E-P-K-M-R-I-A-Q-A-V-V-A-P-V-V-Q-A-K-F-I-V-V-D-Q-E-E-G-L-T-A-T-S-R-G-S-R-G-F-G-H-T-G-E-K


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-G-S-G-Y-A-K-K-K-K-E-A-K-I-M-E-Q-Q-F-L-E-M-E-A-S-L-E-Q-K-R-Y-E-G-Q-A-G-N-G-L-V-S-V-V-I-N-G-K-C-D-I-V-S-I-K-V-Q-P-T-C-L-D-P-E-E-P-E-V-V-E-D-L-F-R-S-A-F-K-E-A-K-E-A-M-D-K-E-M-S-V-M-R-A-G-M-P-F


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-R-E-L-E-Y-Y-G-S-H-I-L-R-R-K-A-D-I-I-P-E-I-T-D-A-T-R-Q-L-V-Q-D-M-Y-E-T-M-V-A-H-K-G-V-G-L-A-A-P-Q-V-G-E-S-L-S-L-F-V-M-C-V-E-G-E-T-E-E-G-D-L-I-F-C-D-F-P-K-V-Y-I-N-P-V-L-S-N-P-S-E-D-L-V-I-G-R-E-G-C-L-S-I-P-G-L-R-A-D-V-Y-R-P-Q-S-I-T-V-T-A-V-N-L-D-G-Q-E-F-T-E-H-L-E-G-F-P-A-R-I-I-M-H-E-N-D-H-L-H-G-V-L-Y-I-D-K-M-E-E-P-K-D-I-K-K-F-K-A-S-L-E-K-I-R-R-R-Y-H-A-H-V-K-P-E-D-R-A-S


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-E-E-I-P-F-E-N-A-M-A-R-L-E-E-I-V-D-L-M-N-Q-P-S-T-S-L-D-S-S-L-K-L-Y-E-E-A-D-A-L-M-R-I-C-E-S-R-I-R-K-A-E-D-R-V-R-E-L-S-E-K-R-N-E-T-L-L-S-E-E-E-S-C-T-H


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-D-S-S-N-E-H-E-T-E-N-P-S-L-P-I-P-D-N-E-I-Q-D-L-Q-Q-E-I-A-T-L-K-A-E-L-K-E-K-N-D-K-Y-L-M-V-L-A-E-S-E-N-A-R-K-R-M-Q-K-E-R-Q-E-M-M-Q-Y-A-V-E-N-A-L-I-D-F-L-V-P-I-E-S-M-E-K-A-L-G-F-A-S-Q-M-S-D-E-V-K-N-W-A-L-G-F-N-M-I-L-Q-Q-F-K-Q-V-F-E-E-K-G-I-V-E-Y-S-S-V-G-Q-K-F-N-P-F-L-H-E-A-V-E-T-E-E-T-T-K-V-P-E-G-T-I-V-E-E-F-S-K-G-Y-K-I-G-E-R-P-I-R-V-A-K-V-K-V-A-K-A-P-A-P-Q-E-K-E-E-V-E-K


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-K-K-V-S-I-Q-V-C-I-S-N-K-Q-N-D-V-P-I-R-I-Q-S-A-K-K-L-V-L-Y-C-L-Q-H-W-E-V-H-T-D-Q-V-Y-I-Y-F-L-D-D-E-S-L-A-Q-L-H-D-E-V-F-S-D-P-S-L-T-D-T-I-T-L-P-I-D-S-P-G-T-S-S-Q-P-H-I-L-G-E-A-F-I-S-P-K-A-A-I-R-F-L-K-D-R-A-E-D-S-D-L-L-Y-E-E-I-S-R-Y-V-I-H-S-L-L-H-M-L-G-Y-D-D-Q-T-P-E-E-R-K-K-M-R-V-K-E-N-Q-A-L-C-M-L-R-E-K-H-A-L-L-S-D


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-P-D-G-E-V-N-K-L-R-D-V-I-D-K-K-I-L-D-A-R-R-V-F-F-S-E-P-V-T-D-K-S-A-A-D-A-I-K-K-L-W-Y-L-E-L-S-H-P-G-Q-P-I-V-F-V-I-N-S-P-G-G-S-V-D-A-G-F-A-V-W-D-Q-I-K-M-M-T-S-P-V-T-T-V-V-T-G-L-A-A-S-M-G-S-V-L-S-L-C-A-A-P-G-R-R-F-A-T-P-H-S-R-I-M-I-H-Q-P-S-I-G-G-P-I-T-G-Q-A-T-D-L-D-I-H-A-R-E-I-L-K-T-K-K-R-I-V-D-V-Y-L-E-A-T-G-Q-P-R-E-V-I-E-K-A-I-D-R-D-M-W-M-T-A-D-E-A-K-D-F-G-L-L-D-G-I-L-F-S-F-D-D-L


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Q-C-P-F-C-N-H-G-E-L-K-V-I-D-S-R-N-A-P-E-A-N-A-I-K-R-R-R-E-C-L-N-C-G-Q-R-F-T-T-F-E-T-V-E-L-T-L-Q-V-L-K-R-D-G-R-Y-E-N-F-Q-E-S-K-L-I-N-G-L-N-A-A-S-S-H-T-R-I-G-Q-D-Q-V-H-A-I-A-S-N-V-K-S-E-L-L-G-K-Q-N-R-E-I-S-T-K-E-I-G-E-L-V-M-K-Y-L-K-K-A-D-M-I-A-Y-I-R-F-A-C-V-Y-R-R-F-K-D-V-G-E-L-M-E-V-L-L-S-A-T-P-D-M-E-K


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-K-S-Y-A-I-I-Q-T-G-S-K-Q-Y-Q-V-S-E-G-D-V-I-D-V-E-L-L-D-G-I-S-E-G-Q-E-I-V-F-D-Q-V-L-F-T-F-D-G-S-K-V-S-L-G-T-P-I-V-K-D-A-V-V-K-G-Q-L-L-S-Q-V-R-G-E-K-V-T-A-Y-K-Y-K-R-R-K-N-Y-H-R-K-T-G-H-R-Q-N-Y-L-R-V-K-I-S-N-L-V-I


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-Q-Q-K-Q-K-I-R-I-R-L-K-G-F-D-Q-G-Q-L-D-R-S-T-A-D-I-V-E-T-A-K-R-T-G-A-R-V-A-G-P-I-P-L-P-T-K-R-E-V-Y-T-V-L-R-S-P-H-V-D-K-K-S-R-E-Q-F-E-I-R-T-H-K-R-L-I-D-I-L-D-P-T-G-K-T-I-D-A-L-K-M-L-A-L-P-A-G-V-D-I-K-I-K-A-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-A-A-E-K-K-V-I-P-A-D-P-I-Y-G-S-V-T-L-E-R-F-I-N-K-V-M-M-H-G-K-K-S-I-A-R-K-I-V-Y-S-A-L-E-R-F-S-K-K-I-G-A-E-N-V-L-E-A-F-K-E-A-L-E-N-A-K-P-L-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-A-A-G-R-R-D-C-L-A-M-K-W-I-I-N-N-A-R-N-K-P-G-K-C-M-E-V-G-L-A-T-E-L-I-D-C-F-N-K-Q-G-A-T-I-K-K-R-E-D-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-K-W


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-I-R-K-K-R-Q-S-S-A-S-R-K-K-S-P-A-L-Q-K-C-P-Q-R-R-G-V-C-L-Q-V-K-T-K-T-P-K-K-P-N-S-A-L-R-K-V-A-W-V-R-L-S-N-G-Q-E-V-I-A-Y-I-G-G-E-G-H-N-L-Q-E-H-S-I-V-L-V-Q-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-C-A-A-V-K-N-R-K-Q-S-R-S-R-Y-G-A-K-R-P-K


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-V-K-H-Q-T-Q-K-K-G-V-K-R-K-Q-L-K-N-I-P-S-G-V-V-H-V-K-A-T-F-N-N-T-I-V-S-I-T-D-P-A-G-N-T-I-S-W-A-S-A-G-K-V-G-Y-S-G-S-R-K-S-S-A-F-A-A-T-M-A-A-Q-D-A-A-K-N-A-M-N-S-G-L-K-E-V-E-V-C-L-K-G-T-G-A-G-R-E-S-A-V-R-A-L-I-A-S-G-L-V-V-S-V-I-R-D-E-T-P-V-P-H-N-G-C-R-P-R-K-R-R-R-V


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-I-K-L-E-S-L-Q-D-P-S-P-R-K-R-R-T-K-L-L-G-R-G-P-S-S-G-H-G-K-T-S-C-R-G-H-K-G-D-G-S-R-S-G-Y-K-R-R-F-G-Y-E-G-G-G-V-P-L-Y-R-R-V-P-T-R-G-F-S-H-K-R-F-D-K-C-V-E-E-I-T-T-Q-R-L-N-V-L-F-N-E-G-E-E-I-T-L-D-A-L-K-E-K-R-A-I-D-K-H-A-I-R-V-K-V-I-V-K-G-E-L-E-K-T-F-I-W-K-D-A-N-V-V-L-S-Q-G-V-R-N-L-I-G-V-A


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-T-L-S-K-N-S-H-K-E-D-Q-L-E-E-K-V-L-V-V-N-R-C-S-K-V-V-K-G-G-R-K-F-S-F-S-A-L-I-L-V-G-D-G-K-G-R-L-G-Y-G-F-A-K-A-N-E-L-T-D-A-I-R-K-G-G-E-A-A-R-K-N-L-I-T-I-E-S-L-E-S-G-S-I-P-H-E-V-L-V-D-Q-D-G-A-Q-L-L-L-K-P-A-K-S-G-T-G-I-V-A-G-S-R-I-R-L-I-L-E-M-A-G-V-K-N-I-V-A-K-S-L-G-S-N-N-P-M-N-Q-V-K-A-A-F-K-A-L-L-S-L-S-S-R-K-D-V-L-Q-R-R-R-V-T-H-D


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-E-N-S-L-F-K-K-S-E-K-K-V-H-R-A-L-R-V-R-K-V-L-R-G-S-S-L-K-P-R-L-C-V-V-K-T-N-K-H-I-Y-V-Q-L-I-D-D-S-I-G-K-T-L-A-S-V-S-T-M-A-K-S-N-K-A-S-G-L-I-K-K-N-Q-D-V-A-K-T-L-G-T-Q-I-A-E-I-G-K-S-L-Q-V-D-R-V-V-F-D-R-G-P-F-K-Y-H-G-I-I-A-M-V-A-D-G-A-R-E-G-G-L-Q-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-K-A-R-D-P-I-V-L-P-Q-G-V-E-V-S-I-Q-N-N-E-I-L-V-K-G-P-K-G-S-L-K-Q-V-L-A-P-E-V-V-V-D-I-K-D-R-E-V-F-V-H-A-A-P-H-V-V-D-R-P-S-R-M-Q-G-L-F-W-A-L-I-S-N-M-V-Q-G-V-N-T-G-F-E-K-R-L-E-M-I-G-V-G-F-R-A-A-V-Q-G-S-V-L-D-L-S-I-G-V-S-H-P-T-K-M-P-I-P-A-E-L-Q-V-S-V-E-K-N-T-L-I-S-V-K-G-I-N-K-Q-L-V-G-E-F-A-A-S-I-R-A-K-R-R-P-E-P-Y-K-G-K-G-I-R-Y-E-N-E-Y-V-R-R-K-A-G-K-A-A-K-T-G-K-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-M-T-S-D-T-I-A-D-L-L-T-R-I-R-N-A-L-K-A-E-H-L-Y-V-D-L-E-H-S-K-M-R-E-A-I-V-R-I-L-K-Q-H-G-F-L-A-H-Y-L-V-K-E-E-N-R-K-R-T-M-R-I-F-L-Q-Y-S-N-D-R-R-P-V-I-R-Q-L-K-R-V-S-K-P-S-R-R-V-Y-V-P-A-A-K-I-P-Y-V-F-G-N-M-G-I-S-V-L-S-T-S-Q-G-V-L-D-G-A-T-A-R-A-K-N-I-G-G-E-L-L-C-L-V-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-R-L-K-K-L-Y-T-E-E-I-R-K-S-L-Q-E-K-F-G-Y-G-N-T-M-Q-I-P-V-L-R-K-I-V-I-S-M-G-L-A-E-A-A-K-D-K-N-L-F-Q-A-H-L-E-E-L-S-M-I-S-G-Q-K-P-L-V-T-K-A-R-N-S-I-A-G-F-K-L-R-E-G-Q-G-I-G-A-K-V-T-L-R-G-Q-R-M-Y-D-F-M-D-R-F-C-N-I-V-S-P-R-I-R-D-F-R-G-F-S-M-K-G-D-G-R-G-C-Y-S-L-G-L-D-D-Q-Q-I-F-P-E-I-D-L-D-R-V-K-R-T-Q-G-M-N-I-T-W-V-T-T-A-Q-T-D-V-E-C-T-T-L-L-E-L-M-G-L-R-F-K-K-A-Q


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-R-Y-S-V-C-V-G-D-T-V-Y-V-L-A-G-N-D-K-G-K-Q-G-K-V-L-S-C-L-R-E-K-N-K-V-V-V-E-G-V-N-V-R-T-K-N-I-K-R-S-Q-E-N-P-K-G-K-R-I-S-I-E-A-P-I-H-V-S-N-V-R-L-S-I-D-G-A-P-A-K-L-S-V-K-V-T-E-N-G-R-E-L-W-N-K-S-P-D-G-T-S-K-L-Y-R-S-V-K-E-R-K-G


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-Q-L-K-V-A-D-N-T-G-A-K-K-V-K-C-F-K-V-L-G-G-S-R-R-R-Y-A-T-V-G-D-I-I-V-C-S-V-R-D-V-E-P-D-S-S-I-K-K-G-D-V-V-K-A-V-I-V-R-T-R-R-D-I-L-R-K-D-G-S-S-L-R-F-D-T-N-S-C-V-I-I-D-E-K-G-N-P-K-G-T-R-I-F-G-P-I-A-R-E-I-R-D-R-G-F-V-K-I-S-S-L-A-P-E-V-I


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-S-E-E-R-G-L-R-K-T-K-V-G-V-V-V-S-S-K-M-D-K-T-V-V-V-R-V-E-R-I-Y-S-H-P-Q-Y-A-K-V-V-R-D-S-K-K-Y-Y-A-H-N-G-L-D-V-S-E-G-D-K-V-K-I-Q-E-T-R-P-I-S-K-L-K-R-W-R-V-V-E-R-V-S


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-F-R-K-Q-Q-K-G-Q-F-A-G-L-S-K-G-A-T-F-V-D-F-G-E-F-G-M-Q-T-L-E-R-G-W-V-T-S-R-Q-I-E-A-C-R-V-A-I-N-R-Y-L-K-R-K-G-K-V-W-I-R-V-F-P-D-K-S-V-T-K-K-P-A-E-T-R-M-G-K-G-K-G-A-P-D-H-W-V-A-V-V-R-P-G-R-I-L-F-E-V-A-N-V-S-R-E-D-A-Q-D-A-L-R-R-A-A-A-K-L-G-I-R-T-R-F-V-K-R-V-E-R-V


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-F-K-A-T-A-R-Y-I-R-V-Q-P-R-K-A-R-L-A-A-G-L-M-R-N-L-S-V-M-E-A-Q-Q-Q-L-N-F-S-Q-L-K-A-G-R-C-L-K-K-V-L-D-S-A-V-A-N-A-V-L-N-E-N-V-K-R-E-Q-L-S-V-I-E-V-R-V-D-A-G-P-V-Y-K-R-A-K-S-K-S-R-G-G-R-S-P-I-L-K-R-T-S-H-L-T-V-I-V-G-E-K-E-R


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-R-S-L-R-K-G-P-F-V-D-H-H-L-I-K-K-V-R-A-M-N-L-L-E-K-K-S-P-I-K-T-W-S-R-R-S-M-I-T-P-E-M-I-G-H-T-F-E-V-H-N-G-K-K-F-L-T-V-F-V-S-E-T-M-V-G-H-K-L-G-E-F-S-P-T-R-I-F-K-S-H-P-V-K-K-G


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-K-D-P-Y-D-V-I-K-R-H-Y-V-T-E-K-A-K-T-L-E-G-L-S-L-G-N-G-E-G-K-K-K-G-S-F-C-K-H-P-K-Y-T-F-V-V-S-C-D-A-T-K-P-L-I-A-Q-A-L-E-S-I-Y-A-D-K-K-V-K-V-K-S-V-N-T-I-C-V-K-P-Q-P-A-R-M-F-R-G-K-R-K-G-K-T-A-G-F-K-K-A-V-V-T-F-Y-E-G-H-S-I-G


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-S-L-T-D-T-E-K-K-M-A-A-A-L-E-F-F-H-K-E-V-R-S-F-R-T-G-K-A-N-P-A-L-V-E-T-V-T-V-D-V-Y-G-T-T-M-R-L-S-D-L-A-S-I-S-V-A-D-T-R-Q-L-V-I-S-P-Y-D-A-N-N-V-S-A-I-S-K-G-I-I-A-A-N-L-N-L-Q-P-D-V-E-G-T-I-V-R-I-K-V-P-E-P-T-A-E-Y-R-N-E-V-I-K-Q-L-R-R-K-S-E-E-A-K-V-A-I-R-N-I-R-R-E-S-N-D-K-L-K-K-D-S-D-L-T-E-D-A-V-K-G-M-E-K-K-V-Q-E-L-T-D-K-F-C-K-Q-I-D-E-I-T-K-Q-K-E-A-E-L-S-S-I


### FUNCTION A probable RNA-binding protein ### SEQUENCE -M-K-D-F-L-A-Y-I-I-K-N-L-V-D-R-P-E-E-V-H-I-K-E-V-Q-G-T-H-T-I-I-Y-E-L-T-V-A-K-P-D-I-G-K-I-I-G-K-E-G-R-T-I-K-A-I-R-T-L-L-V-S-V-A-S-R-N-N-V-K-V-S-L-E-I-M-E-D-K


### FUNCTION Strong inhibitor of bacterial serine proteases such as subtilisin ### SEQUENCE -M-P-N-T-A-R-W-A-V-T-L-T-L-T-A-T-A-V-C-G-P-L-A-G-A-S-L-A-T-P-N-A-A-A-S-G-L-Y-A-P-S-A-L-V-L-T-T-G-H-G-Q-S-A-A-T-A-T-P-E-R-A-V-T-L-N-C-A-P-T-A-S-G-T-H-P-A-A-V-S-A-C-A-E-L-R-A-T-G-G-D-F-D-A-L-S-A-R-S-D-A-M-C-T-R-Q-Y-D-P-V-V-V-T-V-E-G-V-W-Q-G-K-R-V-A-Y-E-R-T-F-A-N-E-C-V-K-N-S-Y-G-T-T-V-F-T-F


### FUNCTION Plays a role in the release of virion progenies by disrupting the host plasma membrane ### SEQUENCE -M-L-S-L-M-V-S-R-D-Q-T-N-D-R-S-D-D-K-P-A-R-S-N-P-T-D-C-S-V-H-T-E-P-S-D-A-N-N-R-T-G-V-H-S-G-R-H-P-R-E-A-H-S-Q-V-R-D-L-D-L-Q-F-D-C-G-G-H-R-V-R-A-N-C-L-F-P-W-L-P-W-L-N-C-G-C-S-L-H-T-A-E-Q-W-E-L-Q-V-R-S-D-A-P-D-C-P-E-P-T-G-Q-L-Q-L-L-Q-A-S-E-S-E-S-H-S-E-V-K-H-T-P-W-W-R-L-C-T-K-W-H-H-K-R-R-D-L-P-R-K-P-E


### FUNCTION The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane ### SEQUENCE -M-S-I-F-K-R-A-K-K-T-V-L-I-P-P-P-H-L-L-S-G-D-E-E-R-V-T-I-L-S-A-E-G-E-I-K-V-T-G-R-R-P-T-T-L-E-E-K-I-Y-Y-S-M-N-L-A-A-A-I-V-G-G-D-L-H-P-S-F-K-S-M-T-Y-L-F-Q-K-E-M-E-F-G-S-T-Q-E-K-V-N-F-G-S-R-K-P-A-P-Q-T-T-Y-Q-V-T-K-A-R-E-V-Y-L-Q-T-Q-P-L-E-K-K-I-P-M-Q-T-Y-S-V-S-T-E-G-A-T-I-T-F-T-G-R-F-L-F-S-S-S-H-V-G-C-D-D-N-R-T-K-L-A-G-L-D-G-F-T-T-S-N-S-Y-Q-R-V-K-D-Y-Y-A-Q-E-T-A-L-A-L-T-F-A-A-P-E-K-R-G-K-E-K


### FUNCTION Plays an essential role for the viral pathogenicity ### SEQUENCE -M-D-H-R-D-I-N-T-N-M-E-A-L-R-E-A-L-R-Y-K-N-E-V-A-G-H-G-F-S-F-D-D-G-D-L-V-W-R-E-E-D-D-A-T-W-R-R-L-C-D-V-V-N-A-L-I-S-S-K-R-M-Q-R-V-L-Y-M-D-L-S-I-T-K-G-E-G-H-L-L-L-V-D-L-Q-G-T-K-N-R-L-Y-K-E-P-R-F-R-R-H-L-I-L-I-E-D-F-L-A-Y-P-R


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-R-H-G-S-I-P-G-T-R-G-H-V-R-P-L-A-L-L-G-D-P-V-L-H-A-P-C-E-E-V-T-D-H-G-P-E-L-A-R-L-V-E-D-M-F-A-T-M-Y-A-A-N-G-V-G-L-A-A-N-Q-I-G-V-P-L-R-V-F-V-Y-D-C-P-D-D-E-D-V-R-H-V-G-H-V-V-N-P-R-L-I-E-A-D-G-V-V-L-R-G-P-E-G-C-L-S-L-P-G-L-E-A-G-T-E-R-Y-D-R-A-V-V-E-G-F-T-T-D-G-E-P-V-R-V-L-G-T-G-W-F-A-R-C-L-Q-H-E-C-D-H-L-D-G-G-V-Y-V-D-R-V-S-G-W-R-H-R-R-V-M-R-Q-A-A-R-A-P-W-N-R-Q-R-A-P-E-P-R


### FUNCTION Plays an essential role for the viral pathogenicity ### SEQUENCE -M-D-H-R-D-T-N-T-N-M-E-A-L-R-E-V-L-R-Y-K-N-E-V-A-G-H-G-F-L-F-D-D-G-D-L-V-W-R-E-E-D-D-A-T-W-R-R-L-Y-D-V-V-N-A-L-I-S-S-K-R-M-Q-R-V-L-Y-M-D-L-S-I-T-K-G-E-G-H-L-L-F-V-D-L-Q-G-T-K-N-R-L-Y-K-E-P-R-F-R-R-H-L-I-L-I-E-D-F-L-A-Y-P-R


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-S-G-K-G-A-P-E-L-S-V-R-N-C-G-D-L-R-V-A-V-I-A-A-Q-W-H-E-K-V-M-D-G-L-V-D-G-A-L-R-A-L-H-E-L-G-I-D-E-P-T-L-L-R-V-P-G-S-F-E-L-P-V-V-A-K-V-L-A-G-R-G-Y-D-A-I-V-A-L-G-V-V-I-R-G-G-T-P-H-F-D-F-V-C-Q-G-V-T-Q-G-L-T-Q-V-S-V-D-T-G-V-P-V-G-F-G-V-L-T-C-D-T-E-E-Q-A-L-D-R-A-G-I-E-G-S-H-E-D-K-G-H-E-A-V-T-A-A-V-A-T-A-A-T-L-R-S-V-S-E-P-W-R


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-S-S-S-I-T-A-P-E-G-I-I-N-P-P-I-D-E-L-L-E-A-T-D-S-K-Y-S-L-V-I-Y-A-A-K-R-A-R-Q-I-N-A-Y-Y-S-Q-L-G-E-G-L-L-E-Y-V-G-P-L-V-D-T-H-V-H-E-K-P-L-S-I-A-L-R-E-I-N-A-G-L-L-T-S-E-P-V-E-G-P-A-Q


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-A-A-R-N-T-A-R-K-R-A-F-Q-I-L-F-E-G-D-Q-R-G-V-D-V-L-T-V-L-A-D-W-I-R-H-S-R-T-D-T-R-Q-P-P-V-S-E-Y-T-M-Q-L-V-E-G-Y-A-K-K-V-N-R-I-D-E-L-I-S-Q-Y-A-V-G-W-T-L-D-R-M-P-V-V-D-R-N-I-L-R-L-G-T-Y-E-L-L-W-V-D-E-T-P-D-A-V-V-L-D-E-A-V-Q-L-A-K-E-F-S-T-D-D-S-P-A-F-V-N-G-L-L-G-R-L-K-E-L-K-P-S-L-R-R-E-E-A


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-T-N-D-L-K-N-G-L-V-L-K-L-D-G-G-Q-L-W-S-V-V-E-F-Q-H-V-K-P-G-K-G-P-A-F-V-R-T-K-L-K-N-V-L-S-G-K-V-V-D-K-T-F-N-A-G-V-K-V-E-T-A-T-I-D-K-R-D-M-Q-F-S-Y-M-D-G-E-Y-F-V-F-M-D-M-D-T-Y-D-Q-L-M-V-D-R-K-S-V-G-D-A-A-N-F-L-I-E-G-F-T-A-T-V-A-Q-H-E-G-E-V-L-F-V-E-L-P-A-A-V-E-L-V-I-Q-E-T-E-P-G-V-Q-G-D-R-S-T-G-G-T-K-P-A-T-L-E-T-G-H-Q-I-Q-V-P-L-F-I-T-T-G-E-K-I-K-V-D-T-R-T-S-D-Y-L-G-R-V-N-S


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-G-M-R-R-G-R-R-L-A-V-D-V-G-D-A-R-I-G-V-A-S-C-D-P-D-G-I-L-A-T-P-V-E-T-V-P-G-R-D-V-P-A-A-H-R-R-L-K-Q-L-V-E-E-Y-E-P-I-E-V-V-L-G-L-P-R-S-L-K-G-G-E-G-P-A-A-V-K-V-R-A-F-A-Q-E-L-A-R-V-I-A-P-V-P-V-R-L-M-D-E-R-M-T-T-V-T-A-S-Q-G-L-R-A-S-G-V-K-S-K-K-G-R-S-V-I-D-Q-A-A-A-V-I-I-L-Q-Q-A-L-E-S-E-R-V-S-G-K-A-P-G-E-G-V-E-V-V-I


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-E-L-V-N-I-T-E-L-L-L-S-R-I-R-D-V-R-D-Y-P-E-P-G-V-V-F-K-D-I-T-P-L-L-A-D-P-A-A-F-T-A-L-T-G-A-L-A-E-L-T-V-R-H-G-A-T-K-I-V-G-L-E-A-R-G-F-I-L-G-A-P-A-A-V-Q-A-G-V-G-F-I-P-V-R-K-A-G-K-L-P-G-A-T-L-S-Q-S-Y-D-L-E-Y-G-S-A-E-I-E-V-H-A-E-D-L-V-A-G-D-R-V-M-V-V-D-D-V-L-A-T-G-G-T-A-E-A-S-L-Q-L-I-R-R-A-G-A-E-V-A-G-V-S-V-L-M-E-L-G-F-L-G-G-R-A-R-L-E-P-A-L-A-G-A-P-L-E-A-L-L-Q-I


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-S-Q-A-Q-E-N-E-H-A-G-P-A-V-P-Q-T-R-T-A-R-H-R-R-I-V-D-I-L-N-R-Q-P-V-R-S-Q-S-Q-L-A-K-L-L-A-D-D-G-L-S-V-T-Q-A-T-L-S-R-D-L-D-E-L-N-A-V-K-I-R-N-N-D-G-D-L-I-Y-A-V-P-S-E-G-G-F-R-T-P-R-V-P-L-G-E-S-A-K-E-E-R-M-R-R-L-S-A-E-L-L-I-S-A-E-A-S-A-N-L-V-V-L-R-T-P-P-G-A-A-Q-F-L-A-S-A-I-D-Q-A-E-L-H-D-I-L-G-T-I-A-G-D-D-T-L-L-L-I-S-R-E-P-T-G-G-Q-A-L-A-D-H-L-L-R-L-A-Q-N-H-H


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-A-V-N-A-H-K-K-R-R-A-I-L-E-A-A-S-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-V-T-H-S-L-V-Y-N-Y-N-D-R-K-K-R-K-G-D-F-R-Q-L-W-I-Q-R-I-N-A-A-A-R-A-N-G-M-T-Y-N-R-L-I-Q-G-L-K-A-A-N-I-E-V-D-R-K-I-L-A-E-L-A-V-N-D-A-G-A-F-A-A-L-V-E-V-A-Q-K-A-L-P-S-D-V-N-A-P-K-A-A


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-F-G-R-L-G-A-P-E-I-I-L-I-L-V-V-I-I-L-L-F-G-A-K-K-L-P-D-M-A-R-S-L-G-K-S-A-R-I-L-K-S-E-A-K-A-M-K-S-E-G-Q-E-S-T-P-A-G-P-P-N-T-D-E-Q-P-P-A-Q-R-T-I-Q-A-A-P-G-D-V-T-S-S-R-P-V-S-E-P-T-D-T-T-K-R


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-G-S-V-R-K-A-S-A-W-L-G-L-V-D-D-N-D-D-E-R-Y-Y-D-D-D-Y-A-E-G-Q-E-S-G-E-A-W-V-T-D-P-R-V-K-V-A-S-E-T-A-E-E-K-G-R-R-I-G-T-V-T-P-D-S-F-R-D-A-R-G-I-G-E-L-F-R-D-G-V-P-V-I-I-N-L-T-A-M-E-P-T-D-A-K-R-V-V-D-F-A-A-G-L-T-F-G-L-R-G-T-I-E-R-V-A-T-R-V-F-L-L-T-P-A-N-T-E-I-V-S-G-E-A-A-G-R-P-T-D-G-F-F-N-Q-S


### FUNCTION Catalyzes the acetylation of L-2,4-diaminobutyrate  with acetyl coenzyme A ### SEQUENCE -M-T-A-A-H-A-D-L-Q-A-E-F-L-E-M-P-E-G-L-R-I-D-R-P-D-V-A-D-G-S-A-L-W-R-I-A-K-D-S-K-T-L-D-L-N-S-S-Y-S-Y-L-L-W-C-R-D-F-A-G-T-T-A-V-A-R-A-A-D-G-T-P-V-G-F-I-T-A-Y-V-R-P-E-R-P-H-T-L-L-V-W-Q-V-A-V-D-A-A-Y-R-G-R-G-L-A-A-R-M-L-D-G-L-T-A-R-V-T-D-E-Y-G-V-T-G-I-E-T-T-I-S-P-G-N-T-A-S-E-R-L-F-T-S-Y-A-Q-R-H-G-A-D-L-E-R-E-V-L-F-E-A-G-L-F-P-D-A-P-H-D-P-E-V-L-Y-R-I-G-P-L-S-H


### FUNCTION Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid , which is an excellent osmoprotectant ### SEQUENCE -M-I-V-R-S-F-K-D-I-E-G-T-D-R-H-V-K-A-A-S-G-T-W-E-S-K-R-I-V-L-A-K-E-K-V-G-F-S-L-H-E-T-V-L-Y-A-G-T-E-T-S-M-W-Y-A-N-H-I-E-A-V-L-C-V-E-G-E-A-E-L-T-D-D-E-T-G-E-K-H-W-I-T-P-G-T-M-Y-L-L-D-G-H-E-R-H-T-M-R-P-K-T-D-F-R-C-V-C-V-F-N-P-P-V-T-G-R-E-D-H-D-E-N-G-V-Y-P-L-L-T-E-P-E-E-V


### FUNCTION Part of cytochrome c oxidase, its function is unknown ### SEQUENCE -M-K-I-Q-G-K-M-F-I-W-L-A-V-F-I-L-A-M-A-I-I-Y-G-V-W-S-K-E-P-A-G-T-T-A-L-F-L-A-F-G-L-S-I-M-I-G-Y-Y-L-A-F-T-A-R-R-V-D-A-G-A-Q-D-N-K-E-A-D-V-A-D-D-A-G-E-V-G-F-F-S-P-H-S-W-Q-P-L-A-L-G-I-G-G-A-L-A-F-M-G-V-V-F-G-W-W-L-L-Y-F-S-A-P-I-I-L-I-G-L-W-G-W-V-F-E-Y-Y-R-G-E-S-R-T-Q


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-I-D-V-N-N-E-S-G-T-E-V-D-E-Q-A-I-L-D-I-A-R-Y-A-L-A-R-M-R-I-H-P-L-S-E-L-S-V-I-V-V-D-A-D-A-M-E-Q-L-H-I-Q-W-M-D-L-P-G-P-T-D-V-M-S-F-P-M-D-E-L-R-P-P-M-K-D-D-D-E-P-P-Q-G-L-L-G-D-I-V-L-C-P-E-V-A-E-R-Q-G-K-E-A-P-T-Q-H-S-M-D-E-E-L-Q-L-L-A-V-H-G-V-L-H-L-L-G-Y-D-H-E-E-P-D-E-K-A-E-M-F-G-L-Q-A-A-I-V-D-G-W-R-A-E-K-G-L-T-G-P-S-P-A-P-T-V-S


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-I-K-R-N-K-T-N-E-K-A-R-L-R-N-K-A-V-K-S-S-L-K-T-A-I-R-K-A-R-E-A-A-A-A-G-D-V-E-K-A-T-E-Y-Q-R-A-A-A-R-Q-L-D-K-A-V-S-K-G-V-I-H-K-N-Q-A-A-N-K-K-S-A-L-A-S-K-V-A-P-L-K-G


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-R-S-G-G-R-Q-H-K-V-A-V-G-D-I-V-E-V-D-K-I-S-T-A-Q-V-G-D-T-V-E-L-S-T-L-L-V-V-D-G-D-A-V-T-S-D-P-W-V-L-A-G-I-K-V-Q-A-E-V-V-D-H-H-K-G-A-K-I-D-I-L-R-Y-K-N-K-T-G-Y-R-R-R-Q-G-H-R-Q-Q-Y-T-A-I-K-V-T-E-I-P-T-A-A-K


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-N-D-R-M-V-W-I-D-C-E-M-T-G-L-S-L-S-D-D-A-L-I-E-V-A-A-L-V-T-D-S-E-L-N-V-L-G-E-G-V-D-I-V-I-R-P-P-D-A-A-L-E-T-M-P-E-V-V-R-T-M-H-T-A-S-G-L-L-D-E-L-A-A-G-T-T-L-A-D-A-E-A-Q-V-L-A-Y-V-R-E-H-V-K-E-P-G-K-A-P-L-C-G-N-S-V-G-T-D-R-G-F-L-A-R-D-M-S-A-L-E-T-Y-L-H-Y-R-I-V-D-V-S-S-V-K-E-L-A-R-R-W-Y-P-R-A-Y-F-N-S-P-E-K-S-G-N-H-R-A-L-A-D-I-R-E-S-I-A-E-L-R-Y-Y-R-E-A-I-F-V-P-Q-P-G-P-D-S-E-T-A-R-T-I-A-A-K-H-V-L-P-A-Q


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-G-R-V-T-A-P-A-P-L-E-I-E-K-T-E-S-A-E-E-V-F-A-V-P-E-P-D-V-P-W-V-T-I-V-H-N-D-P-V-N-L-M-S-Y-V-T-Y-V-F-Q-T-Y-F-G-Y-S-K-D-K-A-T-K-L-M-L-D-V-H-H-K-G-R-A-V-V-S-S-G-T-R-E-E-M-E-R-D-V-Q-A-M-H-G-Y-G-L-W-A-T-L-Q-Q-D-R-K


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-Y-V-P-K-E-S-Q-P-K-Q-G-G-G-A-S-G-K-V-K-D-G-K-R-K-I-V-A-Q-N-K-K-A-R-H-D-Y-A-I-I-D-T-Y-E-A-G-L-V-L-T-G-T-E-V-K-S-L-R-Q-G-R-A-S-L-T-D-G-F-V-Q-I-D-G-N-E-A-W-L-H-N-A-H-I-P-E-Y-S-Q-G-T-W-T-N-H-T-V-R-R-K-R-K-L-L-L-H-R-E-E-I-D-K-L-A-S-K-S-E-E-T-G-H-T-I-V-P-L-A-L-Y-F-K-D-G-R-A-K-A-E-I-A-L-A-R-G-K-K-E-Y-D-K-R-Q-T-L-R-E-K-Q-D-R-R-E-S-D-R-A-I-A-A-A-K-R-K-Q-R-G-E


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-S-I-I-G-V-G-I-D-V-A-E-I-D-R-F-R-A-S-L-E-R-T-P-G-L-A-D-R-L-F-L-E-R-E-L-L-L-P-N-G-E-R-R-G-I-A-S-L-A-A-R-F-A-A-K-E-A-V-A-K-A-L-G-A-P-G-G-L-Y-W-T-D-A-E-V-W-V-E-D-S-G-R-P-R-L-R-V-T-G-T-V-A-A-R-A-A-E-L-G-V-Q-S-W-H-V-S-L-S-H-D-A-G-V-A-S-A-V-V-V-A-E-G


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-Y-S-P-K-P-G-D-I-T-R-Q-W-Y-V-I-D-A-Q-D-V-V-L-G-R-L-A-T-T-A-A-N-I-L-R-G-K-H-K-P-I-Y-A-P-H-V-D-A-G-D-F-V-I-I-I-N-A-D-K-V-H-L-S-G-N-K-K-T-Q-K-L-A-Y-R-H-S-G-Y-P-G-G-L-R-S-V-R-Y-D-E-L-L-A-K-N-P-E-K-A-V-E-K-A-I-K-G-M-I-P-K-N-T-L-G-R-Q-V-L-S-K-L-K-V-Y-S-G-D-Q-H-P-H-A-A-Q-Q-P-V-P-F-E-I-T-Q-V-A-Q


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-P-P-K-G-R-Q-G-A-A-K-K-V-R-R-K-E-K-K-N-V-A-H-G-H-A-H-I-K-S-T-F-N-N-T-I-V-S-I-T-D-P-S-G-N-V-I-S-W-A-S-A-G-H-V-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-S-A-A-R-R-A-Q-E-H-G-M-R-K-V-D-V-F-V-K-G-P-G-S-G-R-E-T-A-I-R-S-L-Q-A-T-G-L-E-V-G-S-I-Q-D-V-T-P-T-P-H-N-G-C-R-P-P-K-R-R-R-V


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-E-N-N-P-L-K-I-H-N-L-R-P-A-P-G-A-K-T-A-K-T-R-V-G-R-G-E-A-S-K-G-K-T-A-G-R-G-T-K-G-T-K-A-R-Y-Q-V-P-E-R-F-E-G-G-Q-M-P-L-H-M-R-L-P-K-L-K-G-F-K-N-P-F-R-T-E-Y-Q-V-V-N-L-D-K-L-T-A-L-Y-P-E-G-G-E-V-T-V-E-G-L-V-A-K-G-A-V-R-K-N-S-L-V-K-V-L-G-Q-G-E-I-S-V-A-L-Q-V-T-V-D-A-V-S-G-S-A-K-E-K-I-T-A-A-G-G-T-V-T-E-L-V


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-Y-G-V-K-I-A-K-G-D-A-Y-K-R-A-A-I-K-R-R-H-I-R-I-R-K-H-I-S-G-T-A-E-R-P-R-L-V-V-T-R-S-N-R-H-I-V-A-Q-V-I-D-D-V-K-G-H-T-L-A-S-A-S-T-L-D-T-T-I-R-G-G-E-S-D-K-S-A-Q-A-K-S-V-G-A-L-V-A-E-R-A-K-A-A-G-V-E-A-V-V-F-D-R-G-G-N-Q-Y-A-G-R-I-A-A-L-A-D-A-A-R-E-A-G-L-K-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-L-P-I-T-V-P-A-G-V-D-V-T-I-D-G-R-T-V-Q-V-K-G-P-K-G-S-L-S-H-T-I-A-A-P-I-E-I-A-K-G-E-D-G-V-L-N-V-T-R-P-N-D-E-R-Q-N-K-A-L-H-G-L-S-R-T-L-V-A-N-M-I-T-G-V-T-Q-G-Y-V-K-K-L-E-I-S-G-V-G-Y-R-V-L-A-K-G-S-N-L-E-F-S-L-G-Y-S-H-S-I-T-V-E-A-P-E-G-I-T-F-K-V-E-A-P-T-R-F-S-V-E-G-I-D-K-Q-K-V-G-E-V-A-A-N-I-R-K-L-R-K-P-D-P-Y-K-A-K-G-V-K-Y-E-G-E-V-I-R-R-K-V-G-K-A-G-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-I-A-D-M-L-T-R-L-R-N-A-N-S-A-Y-H-D-T-V-G-M-P-H-S-K-I-K-S-H-I-A-E-I-L-Q-Q-E-G-F-I-T-G-W-K-V-E-D-A-E-V-G-K-N-L-V-L-E-L-K-F-G-P-N-R-E-R-S-I-A-G-I-K-R-I-S-K-P-G-L-R-V-Y-A-K-S-T-N-L-P-K-V-L-G-G-L-G-V-A-I-I-S-T-S-H-G-L-L-T-D-K-Q-A-G-K-K-G-V-G-G-E-V-L-A-Y-V-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-T-T-T-T-P-R-L-K-T-K-Y-R-E-E-I-A-G-K-L-Q-E-E-F-S-Y-E-N-V-M-Q-T-P-G-L-V-K-I-V-V-N-M-G-V-G-D-A-A-R-D-S-K-L-I-D-G-A-I-R-D-L-T-T-I-T-G-Q-K-P-A-V-T-K-A-R-K-S-I-A-Q-F-K-L-R-E-G-Q-P-I-G-A-H-V-T-L-R-G-D-R-M-W-E-F-L-D-R-T-L-S-L-A-L-P-R-I-R-D-F-R-G-L-S-P-K-Q-F-D-G-R-G-N-Y-T-F-G-L-T-E-Q-V-M-F-H-E-I-D-Q-D-K-I-D-R-V-R-G-M-D-I-T-V-V-T-T-A-T-N-D-A-E-G-R-A-L-L-R-H-L-G-F-P-F-K-E-A


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-I-K-K-G-D-T-V-Q-V-I-T-G-K-D-K-G-K-Q-G-K-V-I-A-A-Y-P-R-D-E-R-V-L-V-E-G-V-N-R-V-K-K-H-T-K-A-G-P-T-A-G-G-S-Q-A-G-G-I-V-T-T-E-A-P-I-H-V-S-N-V-Q-L-V-V-E-K-D-G-N-K-V-V-T-R-V-G-Y-R-F-D-D-E-G-N-K-I-R-V-A-K-R-T-G-E-D-I


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-R-V-A-D-N-T-G-A-K-E-I-L-C-I-R-V-L-G-G-S-G-R-R-Y-A-G-I-G-D-V-I-V-A-T-V-K-D-A-I-P-G-G-N-V-K-K-G-D-V-V-K-A-V-I-V-R-T-V-K-E-R-R-R-P-D-G-S-Y-I-R-F-D-E-N-A-A-V-I-L-K-N-D-G-D-P-R-G-T-R-I-F-G-P-V-G-R-E-L-R-E-K-K-F-M-K-I-I-S-L-A-P-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-S-N-V-T-E-T-N-E-Q-R-G-F-R-K-T-R-E-G-L-V-V-S-D-K-M-D-K-T-V-V-V-A-V-E-D-R-V-K-H-A-L-Y-G-K-V-I-R-R-T-N-K-L-K-A-H-D-E-Q-N-A-A-G-V-G-D-R-V-L-L-M-E-T-R-P-L-S-A-T-K-R-W-R-V-V-E-I-L-E-K-A-K


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-I-P-R-R-V-K-H-R-K-Q-H-H-P-K-R-R-G-Q-A-K-G-G-T-Q-V-S-F-G-E-Y-G-I-Q-A-L-T-P-A-Y-V-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-H-I-K-R-G-G-K-V-W-I-N-I-Y-P-D-R-P-L-T-K-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-W-W-I-A-N-V-H-P-G-R-V-M-F-E-L-S-Y-P-N-E-K-I-A-R-E-A-L-T-R-A-A-H-K-L-P-M-K-C-R-I-V-K-R-E-A-G-E-A


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-R-A-Q-A-R-Y-I-R-V-T-P-M-K-A-R-R-V-V-D-L-I-R-G-M-D-A-T-E-A-Q-A-V-L-R-F-A-P-Q-A-A-S-V-P-V-G-K-V-L-D-S-A-I-A-N-A-A-H-N-Y-D-H-T-D-A-D-S-L-F-I-S-E-A-Y-V-D-E-G-P-T-L-K-R-F-R-P-R-A-Q-G-R-A-Y-R-I-R-K-R-T-S-H-I-T-V-V-V-S-S-K-E-G-T-R


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-V-D-D-H-L-I-K-K-V-D-A-Q-N-E-A-G-S-K-N-V-I-K-T-W-S-R-R-S-M-I-I-P-A-M-L-G-H-T-I-A-V-H-N-G-K-T-H-I-P-V-F-V-T-E-S-M-V-G-H-K-L-G-E-F-S-P-T-R-T-F-R-G-H-V-K-D-D-R-K-S-K-R-R


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-A-P-K-R-P-V-I-I-D-P-V-Y-G-S-P-L-V-T-S-L-I-N-K-V-L-L-N-G-K-R-S-T-A-E-R-I-V-Y-G-A-M-E-G-L-R-E-K-T-G-N-D-P-I-I-T-L-K-R-A-L-E-N-I-K-P-T-L-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-I-E-V-K-P-G-R-A-N-T-L-A-L-R-W-L-V-G-Y-S-R-A-R-R-E-K-T-M-T-E-R-L-L-N-E-L-L-D-A-S-N-G-L-G-A-A-V-K-K-R-E-D-T-H-K-M-A-E-S-N-K-A-F-A-H-Y-R-W


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-T-K-L-S-Q-E-E-L-L-E-Q-F-E-S-L-T-L-I-E-L-A-E-F-V-K-A-F-E-E-K-F-D-V-T-A-A-A-A-V-A-A-A-P-A-G-P-V-A-A-A-E-A-A-E-E-Q-D-E-F-D-V-I-L-T-G-A-G-D-K-K-I-Q-V-I-K-V-V-R-E-L-T-S-L-G-L-K-E-A-K-D-L-V-D-G-A-P-K-P-V-L-E-K-V-A-K-E-A-A-E-K-A-A-E-S-L-K-G-A-G-A-S-V-E-V-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-R-P-D-K-A-A-A-V-A-E-L-A-D-Q-F-R-S-S-N-A-A-V-L-T-E-Y-R-G-L-T-V-A-Q-L-K-T-L-R-R-S-L-G-E-D-A-Q-Y-A-V-V-K-N-T-L-T-K-I-A-A-N-E-A-G-I-N-T-L-D-D-L-F-N-G-P-T-A-V-A-F-I-T-G-D-P-V-V-S-A-K-G-L-R-D-F-A-K-D-N-P-N-L-V-I-K-G-G-V-L-D-G-K-A-L-S-A-D-E-I-K-K-L-A-D-L-E-S-R-E-V-L-L-A-K-L-A-G-A-F-K-G-K-Q-S-Q-A-A-S-L-F-Q-A-L-P-S-K-F-V-R-T-A-E-A-L-R-A-K-K-A-E-Q-G-G-A-E