### FUNCTION Probable methyltransferase ### SEQUENCE -M-N-L-V-Q-L-G-K-L-H-E-N-V-L-D-A-G-C-E-P-N-R-N-A-R-Y-L-A-S-L-G-Y-K-V-V-G-I-D-I-S-E-R-A-I-S-K-A-I-D-K-T-S-S-E-K-S-N-V-N-F-N-Q-R-D-F-S-R-L-N-E-F-K-G-H-F-D-T-V-I-D-I-G-C-F-H-S-I-L-N-S-D-H-E-P-H-T-A-S-L-S-H-I-C-H-S-D-S-S-V-F-L-R-A-F-S-E-T-N-K-S-R-Y-R-R-W-Q-G-H-K-R-Y-S-L-A-L-K-R-N-N-V-K-K-L-S-L


### FUNCTION Plays an essential role in the assembly of succinate dehydrogenase  to ubiquinol Promotes maturation of the iron-sulfur protein subunit sdh2 of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants May act together with SDHAF1 ### SEQUENCE -M-N-N-I-T-K-L-M-K-Q-K-N-I-L-T-P-P-L-P-L-Y-R-R-V-L-R-A-H-R-Y-H-L-G-A-E-E-R-A-L-G-D-E-Y-V-K-A-E-F-R-R-H-R-N-V-T-N-P-L-H-L-V-G-F-L-S-S-W-E-R-Y-A-D-A-L-E-N-E-S-W-K-Q-E-K-Y-S-N-T-D-L-L-E-S-L-N-D-Q-Q-I-G-Q-L-Y-E-L-S-K-A-L-Q-E-Q-K-K-S-E


### FUNCTION Functions together with the other V-type ATPase assembly factors in the endoplasmic reticulum to efficiently assemble the V-type ATPase membrane sector V ### SEQUENCE -M-S-Y-W-V-E-L-W-E-S-I-F-T-P-G-V-T-P-V-L-A-K-S-A-H-V-A-C-G-A-L-V-A-V-F-L-G-L-Y-I-G-T-K-S-I-H-C-L-I-L-F-F-L-A-I-C-L-W-L-S-L-T-W-F-L-V-E-L-A-H-A-R-V-N-N-D-L-Q-M-S-S-Q-S-A-N-K-N-D-D-N-S-N-N-Q-N-P-S-N-N-K-E-M-S-D-K-E-S-D-S-A-T-T-T-Q-T-F-S-V-P-E-E-L-L-R-A-R-T-T-A-N-N-S


### FUNCTION Component of the mitochondrial ribosome , a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane ### SEQUENCE -M-S-I-M-K-P-T-T-R-F-F-R-F-N-S-L-E-L-A-V-S-P-F-Q-R-I-Y-G-Q-L-R-F-L-R-K-Q-P-K-P-F-L-V-K-L-L-N-N-E-V-S-K-L-G-R-Q-G-D-V-V-S-V-T-R-G-Y-Y-R-N-T-L-F-P-K-K-Q-A-I-A-V-D-A-L-K-S-M-K-A-H-L-L-Q-G-S-E-F-S-T-K-T-K-E


### FUNCTION Plays a role in the regulation of membrane potential ### SEQUENCE -M-N-S-E-K-I-I-E-V-I-I-A-I-F-L-P-P-V-A-V-F-M-K-C-G-A-T-T-P-L-W-I-N-L-V-L-C-I-F-I-W-F-P-A-I-L-H-A-L-Y-V-V-L-K-D


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -E-G-T-P-S-L-G-K-R-H-N-K-S-H-T-L-C-N-R-C-G-R-R-S-F-H-V-Q-K-K-T-C-S-S-C-G-Y-P-A-A-K-M-R-S-H-N-W-A-L-K-A-K-R-R-R-T-T-G-T-G-R-M-A-Y-L-K-H-V-T-R-R-F-K-N-G-F-Q-T-G-V-A-K-A-Q-T-P-S-A


### FUNCTION Subunit of the oligosaccharyl transferase  All subunits are required for a maximal enzyme activity ### SEQUENCE -M-I-T-D-E-Q-L-N-T-I-A-L-T-F-G-F-A-S-I-I-L-I-I-I-Y-H-A-I-S-T-N-V-H-K-L-E-D-E-T-P-S-S-S-F-T-R-T-N-T-T-E-T-T-V-A-S-K-K-K-K


### FUNCTION The complex LTO1YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly  complex machinery May be required for biogenesis of the large ribosomal subunit and initiation of translation ### SEQUENCE -M-T-C-Q-E-D-C-S-C-K-N-N-E-A-P-T-T-K-T-T-A-T-T-T-N-V-G-D-G-P-G-P-G-P-I-P-G-N-N-D-D-D-D-D-D-I-W-S-D-D-D-T-K-L-I-P-E-N-D-I-I-R-S-H-Y-K-K-G-Y-V-D-G-I-T-Q-A-K-E-S-S-L-Q-Q-G-F-D-D-G-Y-P-E-G-A-K-L-G-I-K-V-G-E-I-L-A-N-L-I-N-Q-C-K-D-R-N-R-Q-G-D-D-D-D-D-D-D-D-E-Q-S-V-R-F-N-E-A-K-K-E-L-N-I-V-N-V-L-K-K-S-Y-F-D-E-D-L-N-L-K-K-S-N-D-N-K-E-T-D-E-S-Y-H-E-L-I-N-K-W-E-N-E-M-K


### FUNCTION Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits Has a physiological role leading to 18S rRNA stability ### SEQUENCE -M-E-N-D-K-G-Q-L-V-E-L-Y-V-P-R-K-C-S-A-T-N-R-I-I-K-A-K-D-H-A-S-V-Q-I-S-I-A-K-V-D-E-D-G-R-A-I-A-G-E-N-I-T-Y-A-L-S-G-Y-V-R-G-R-G-E-A-D-D-S-L-N-R-L-A-Q-Q-D-G-L-L-K-N-V-W-S-Y-S-R


### FUNCTION Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH At alkaline ambient pH, activates transcription of alkaline-expressed genes ### SEQUENCE -V-C-E-R-H-V-G-R-K-S-T-N-N-L-N-L-T-C-Q-W-G-S-C-R-T-T-T-V-K-R-D-H-I-T-S-H-I-R-V-H-V-P-L-K-P-H-K-C-D-F-C-G-K-A-F-K-R-P-Q-D-L-K-K-H-V-K-T-H-A-D-D


### FUNCTION Facilitates protein transport into the nucleus Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import ### SEQUENCE -M-S-V-D-F-N-A-V-A-T-E-F-C-N-F-Y-Y-N-Q-F-D-S-D-R-S-Q-L-G-N-L-Y-R-N-E-S-M-L-T-F-E-T-S-Q-L-Q-G-A-R-D-I-V-E-K-L-A-S-L-P-F-Q-K-V-A-H-R-I-S-T-L-D-A-Q-P-A-S-A-N-G-D-I-L-V-M-V-T-G-E-L-L-I-D-E-E-Q-N-A-Q-R-Y-S-Q-V-F-H-L-I-P-D-N-G-S-Y-Y-V-F-N-D-I-F-R-L-N-Y-S


### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-E-P-E-I-K-I-V-N-V-V-V-S-T-Q-I-G-T-D-I-D-L-E-Y-A-A-D-I-L-D-N-A-E-Y-E-P-E-Q-F-P-G-L-V-C-R-L-S-D-P-K-V-A-L-L-I-F-R-S-G-K-L-N-C-T-G-A-K-S-K-E-D-A-E-I-A-I-K-K-I-I-K-E-L-K-D-A-G-M-D-I-I-D-N-P-E-V-N-V-Q-N-M-V-A-T-A-D-L-G-I-E-P-N-L-D-D-I-S-T-L-E-G-T-E-Y-E-P-E-Q-F-P-G-L-V-Y-R-L-S-D-P-K-V-V-V-L-I-F-G-S-G-K-V-V-I-T-G-L-K-K-K-D-D-A-Y-L-A-L-D-K-I-L-S-T-L-K-E-L-E-E-E-Y-Y


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-N-S-C-K-R-F-P-R-S-A-R-I-C-L-R-S-E-Y-Y-V-A-F-E-Q-G-R-R-Y-S-S-V-L-L-R-L-H-H-L-P-T-S-G-P-V-R-L-G-L-V-V-S-R-R-V-D-I-R-A-V-N-R-N-R-I-K-R-A-L-R-E-V-M-R-Q-I-A-Y-K-L-V-P-G-D-Y-V-V-V-V-R-Q-T-A-K-D-V-S-N-A-E-L-S-V-A-L-L-S-L-L-R-R-I-G-A-L-P-L-A-P-I-D-N-A-M-L-P-F-F-E-R-N-C-S-R-K


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-L-G-L-R-L-I-V-G-L-G-N-P-G-S-E-H-T-K-T-R-H-N-A-G-F-R-F-V-D-G-L-V-Q-R-E-G-Q-R-W-M-L-E-S-K-L-F-A-H-V-A-R-V-F-I-A-G-Q-W-V-W-L-L-R-P-V-T-F-M-N-L-S-G-K-S-I-C-A-G-L-S-F-W-K-I-K-P-E-Q-M-L-V-A-H-D-E-L-D-F-P-P-G-A-V-R-L-K-F-D-G-G-H-G-G-Q-N-G-L-R-D-I-T-K-L-L-G-H-G-R-F-H-R-L-R-V-G-I-G-H-P-G-H-K-D-R-V-V-N-W-V-L-G-C-P-T-C-E-E-N-I-A-I-D-A-A-L-E-R-A-S-A-V-L-P-L-V-V-A-G-D-F-D-E-A-M-K-K-L-H-T-V-V


### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-K-R-W-Y-V-V-H-A-Y-S-G-F-E-K-S-V-A-Q-A-L-R-D-R-I-S-R-I-E-I-Q-D-R-F-G-D-V-L-V-P-A-E-E-V-V-E-M-R-S-G-Q-K-R-R-S-E-H-K-F-F-P-G-Y-V-L-I-Q-I-E-T-Y-Y-E-G-G-V-P-R-I-D-N-E-C-W-H-L-V-K-E-T-P-K-V-M-G-F-I-G-G-T-A-D-R-P-L-P-I-S-S-D-E-A-D-A-I-L-R-R-V-Q-D-G-A-E-K-P-R-P-K-V-L-F-E-P-G-Q-M-V-R-V-I-D-G-P-F-N-D-F-D-G-L-V-E-E-V-N-Y-E-K-N-R-L-R-V-A-V-L-I-F-G-R-P-T-P-V-D-L-E-F-G-Q-V-Q-K-S


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-I-A-Y-I-K-L-Q-V-K-A-G-Q-A-S-P-S-P-P-V-G-P-A-L-G-Q-R-G-L-N-I-M-D-F-C-K-A-F-N-A-A-T-Q-K-V-E-Q-G-L-P-I-P-V-V-I-T-A-Y-S-D-R-T-F-T-F-I-T-K-T-P-P-A-S-I-L-L-K-K-I-V-G-I-Q-S-G-S-K-R-P-N-T-E-K-V-G-K-V-T-R-K-Q-L-E-D-I-A-K-T-K-E-L-D-M-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-V-V-E-G


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-I-F-Q-K-Q-E-V-V-E-E-L-A-G-V-A-T-K-A-H-S-L-I-V-A-E-Y-A-G-I-T-V-S-Q-M-T-A-M-R-K-Q-A-R-E-S-G-V-Y-L-K-V-V-K-N-K-L-A-A-R-A-L-G-D-T-E-Y-A-V-I-K-E-K-L-I-G-P-L-L-Y-A-F-S-L-E-D-P-G-A-A-G-R-L-I-K-E-F-S-K-K-H-D-K-L-K-S-K-T-V-S-L-G-G-V-L-Y-P-A-G-H-V-D-V-L-A-S-L-P-T-R-L-Q-A-L-A-M-L-A-R-V-L-S-E-P-V-T-L-F-A-R-A-I-K-A-V-A-D-D-K-S-E-T-V-A-V-S-A-P-E-A-S-Q-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-L-T-N-E-K-I-V-E-A-I-A-E-K-S-I-M-E-V-M-E-L-V-K-A-I-E-D-K-F-G-V-S-A-A-A-P-V-M-V-S-G-S-A-A-A-A-A-P-V-E-E-Q-T-E-F-T-V-T-L-K-E-A-G-A-K-K-V-E-V-I-K-A-V-R-A-V-T-G-L-G-L-K-E-A-K-D-L-T-E-A-G-G-I-L-K-E-A-V-S-K-E-E-A-E-K-V-K-K-E-L-E-A-A-G-A-T-V-E-V-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-G-S-T-P-Q-R-N-V-L-P-D-P-K-Y-G-S-E-T-I-A-R-F-I-N-M-V-M-K-S-G-K-K-S-V-A-E-K-I-V-Y-G-A-M-N-V-I-G-E-K-N-S-N-A-I-E-L-L-Q-K-A-L-D-N-V-S-P-A-V-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-A-S-R-R-M-A-L-A-M-R-W-L-I-D-S-S-R-K-R-G-E-N-S-M-P-H-K-L-A-A-E-L-L-D-A-S-E-S-R-G-G-A-I-K-K-R-E-E-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-R-W


### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-Q-I-S-D-R-A-K-A-H-F-L-R-L-I-Q-R-E-G-V-P-G-M-G-V-R-L-S-A-V-D-P-G-T-A-R-A-D-A-R-L-E-F-A-E-P-S-E-L-V-G-D-E-W-L-I-D-C-G-D-F-T-L-Y-V-A-S-A-S-V-A-W-L-D-S-A-E-I-D-Y-V-T-Q-A-T-G-S-Q-Q-L-I-I-K-A-P-K-I-K-G-Q-E-L-S-Q-V-A-S-L-V-E-R-V-C-W-V-V-E-N-E-I-N-P-Q-L-A-S-H-G-G-R-V-E-V-Q-E-V-S-A-E-G-V-V-L-L-R-F-G-G-G-C-H-G-C-G-M-V-D-V-T-L-K-Q-G-V-E-K-T-L-M-E-R-V-H-G-V-I-A-V-R-D-A-T-D-H-S-T-G-A-A-P-Y-I-S-R-N-F-A-S


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-K-F-F-R-R-R-K-F-C-K-F-T-A-E-G-I-K-E-I-D-Y-K-D-L-N-T-L-R-Q-Y-L-T-E-N-G-K-I-V-P-S-R-V-T-G-T-K-S-K-Y-Q-R-Q-L-T-T-A-V-K-R-A-R-F-L-A-L-I-P-Y-T-D-N-H-D-I


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-L-I-L-L-Q-K-V-A-N-L-G-A-L-G-D-K-V-T-V-K-P-G-Y-G-R-N-F-L-L-P-K-G-V-A-V-P-A-T-E-A-N-L-A-A-F-Q-A-K-R-A-E-Y-E-A-K-A-K-S-E-L-D-Q-A-Q-A-R-A-A-K-F-E-G-A-S-V-T-V-S-A-H-A-S-T-E-G-K-L-Y-G-S-V-G-A-R-D-I-A-E-A-F-T-A-V-G-L-P-L-E-K-K-E-V-I-L-G-E-G-P-F-R-L-I-G-E-Y-D-V-L-L-H-L-H-A-D-V-E-S-T-V-K-V-I-V-Q-G-V-P


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-I-L-T-K-R-Q-A-H-L-K-S-D-D-V-D-L-A-V-K-S-L-L-E-M-M-G-G-A-L-S-E-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-P-P-R-C-G-R-N-P-K-T-G-E-S-V-A-L-P-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-E-R-V-A-S-V-V-P-L-A-E-C-G-D-I-T-E


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-L-V-T-G-G-K-Q-Y-R-V-V-Q-G-E-T-L-R-V-E-K-L-D-V-E-T-G-S-D-V-T-F-N-S-V-L-L-M-G-S-S-D-G-I-H-V-G-E-A-L-K-D-A-S-V-T-A-K-V-V-A-H-G-R-A-R-K-V-R-I-I-K-F-R-R-R-K-H-H-M-K-H-Q-G-H-R-Q-Y-Y-T-E-I-Q-I-T-G-I-S-G-P-A-K-Q


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-N-N-K-H-P-E-N-K-A-K-S-T-T-T-P-K-T-I-A-L-N-K-R-A-R-H-E-Y-H-L-I-E-R-H-E-A-G-L-E-L-Q-G-W-E-V-K-A-I-R-A-G-R-A-N-L-A-D-G-Y-A-Y-V-R-D-G-E-I-F-L-I-G-A-Q-I-T-P-L-I-Q-A-S-T-H-V-V-A-N-D-R-R-T-R-K-L-L-L-H-R-R-Q-I-D-T-L-I-G-R-V-Q-R-E-G-F-T-L-V-P-T-A-M-Y-W-S-K-N-R-V-K-M-E-I-A-L-A-K-G-K-Q-A-H-D-K-R-H-A-E-K-E-R-E-W-Q-R-D-K-Q-R-I-M-R-A-H-N-R-N-A


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-N-Q-D-H-P-E-C-D-S-E-E-L-T-Q-N-S-P-E-T-D-P-L-K-V-E-V-E-T-L-R-G-E-I-A-S-I-K-A-D-V-L-R-E-R-A-E-L-E-N-Q-R-K-R-L-I-R-D-V-E-Q-A-R-K-F-A-N-E-K-L-L-G-E-L-L-P-V-F-D-S-L-D-A-G-L-T-A-S-G-S-E-P-S-P-L-R-D-G-L-E-L-T-Y-K-Q-L-L-K-V-A-T-D-N-G-L-M-L-L-D-P-V-G-Q-L-F-N-P-E-H-H-Q-A-I-S-Q-T-E-V-T-D-V-E-P-G-Y-V-I-Q-V-F-Q-K-G-Y-L-L-N-E-R-L-L-R-P-A-L-V-V-V-A-K-Q-D


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-S-P-I-T-I-L-L-I-G-I-A-M-S-T-D-A-F-A-A-A-I-G-K-G-A-A-I-G-K-P-R-L-R-D-A-L-Y-V-A-V-I-F-G-V-I-E-T-A-T-P-I-A-G-W-L-L-G-Q-I-A-S-H-Y-I-A-T-F-D-H-W-I-A-F-G-L-L-S-G-L-G-I-H-M-I-V-N-G-L-K-N-N-G-N-T-C-K-D-N-A-D-T-H-N-R-N-S-R-W-L-P-L-A-A-T-A-L-A-T-S-I-D-A-A-A-I-G-I-S-L-A-F-L-D-I-H-I-S-I-V-A-A-V-I-G-L-C-T-F-T-M-V-I-F-G-V-M-L-G-R-V-L-G-T-F-V-G-N-R-A-E-I-V-G-G-I-I-L-I-I-V-G-S-T-I-L-Y-E-H-L-S-N-N-G


### FUNCTION This protein is an aporepressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription ### SEQUENCE -M-S-R-E-Q-A-F-E-M-L-I-K-I-L-C-K-T-D-S-T-D-D-M-K-L-I-L-E-C-I-L-T-R-S-E-M-E-D-L-I-D-R-I-R-I-Y-N-E-L-L-N-T-N-N-S-Q-R-E-V-A-S-K-L-G-V-S-I-T-K-I-T-R-G-A-A-N-L-Q-D-N-N-I-K-D-F-L-R-K-K-I-S-Y


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-I-G-R-L-R-G-V-L-T-S-K-T-P-P-W-L-V-V-D-V-C-G-V-G-Y-E-L-E-V-P-M-S-T-F-Y-E-L-P-N-V-G-Y-E-V-N-L-F-T-H-Y-T-Q-K-D-D-S-A-A-L-Y-G-F-L-S-E-S-E-R-R-L-F-R-H-L-Q-R-V-S-G-I-G-T-K-I-A-L-A-V-L-S-S-V-S-V-D-T-F-A-G-L-I-Q-A-G-D-V-N-A-L-T-V-I-P-G-I-G-K-K-T-A-E-R-M-L-V-E-L-R-D-R-A-A-D-F-N-N-G-I-S-T-S-G-K-L-N-L-D-T-V-S-E-A-A-L-A-L-Q-Q-L-G-Y-K-P-A-E-A-A-R-M-A-R-D-A-G-T-E-S-D-D-V-A-S-V-I-K-K-A-L-Q-A-A-L-R


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-T-H-L-L-E-Q-L-I-D-A-F-R-I-L-P-G-V-G-Q-K-T-A-Q-R-M-A-Y-H-V-L-E-R-E-R-E-G-G-Q-R-L-A-D-V-L-S-R-A-I-E-K-I-G-H-C-T-E-C-R-D-F-S-E-T-K-I-C-A-I-C-A-N-Y-S-R-D-R-H-Q-L-C-V-V-E-S-P-P-D-R-L-A-I-E-Q-A-T-G-Y-R-G-L-Y-F-I-L-Q-G-R-L-S-P-L-D-G-I-G-P-H-E-L-G-L-D-H-L-G-Q-R-L-A-A-G-E-V-T-E-L-I-I-A-T-N-A-T-V-E-G-E-T-T-A-H-Y-L-A-L-L-A-R-Q-H-G-I-R-P-S-R-L-A-Q-G-L-P-L-G-G-E-L-E-Y-L-D-R-G-T-L-S-H-A-F-G-T-R-T-E-V-V


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-R-G-N-I-A-Q-L-M-Q-Q-A-Q-K-M-Q-E-N-L-Q-R-A-Q-E-E-L-A-K-L-E-V-T-G-S-A-G-G-G-M-V-S-V-I-L-S-G-T-K-E-C-R-K-V-R-I-D-P-S-I-L-N-D-Q-E-M-I-E-D-L-I-A-A-A-F-N-D-A-S-N-K-V-D-T-E-S-K-E-R-M-G-S-A-T-L-G-M-S-L-P-P-G-F-K-L-P-F


### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-D-E-I-T-N-G-A-A-K-P-T-E-A-I-S-G-P-T-F-T-I-E-K-I-Y-I-K-D-V-S-F-E-A-P-N-S-P-A-V-F-N-E-A-G-Q-P-E-L-Q-L-N-L-N-Q-R-V-Q-R-L-N-E-N-A-F-E-L-V-L-H-V-T-L-T-C-T-A-A-G-K-T-A-Y-V-V-E-V-Q-Q-A-G-V-F-G-L-F-G-L-D-Q-H-A-I-G-V-L-L-G-T-Q-C-P-N-I-L-F-P-Y-V-R-S-L-V-S-D-L-I-Q-I-G-G-F-P-P-F-Y-L-Q-P-I-N-F-D-A-L-Y-A-E-T-L-R-Q-R-A-Q-N-E-K-E-G-S-Q-I-S-S-H-P-A-G-N-A


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-T-T-F-T-A-K-N-E-T-V-Q-R-D-W-Y-L-V-D-A-E-G-K-T-L-G-R-L-A-T-E-L-A-R-R-L-L-G-K-T-K-P-V-Y-T-T-H-V-D-T-G-D-Y-L-V-V-I-N-A-E-K-V-V-V-T-G-K-K-L-T-D-K-Y-Y-H-R-F-T-G-Y-V-G-N-L-K-S-E-S-L-G-Q-A-L-Q-R-H-P-E-R-V-L-E-I-A-V-K-G-M-L-P-K-G-P-L-G-R-A-M-Y-R-K-L-K-V-Y-T-G-S-K-H-P-H-A-A-Q-Q-P-Q-V-L-D-I


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-I-T-V-E-D-C-L-E-V-V-N-N-R-F-E-L-V-M-M-A-S-K-R-A-R-Q-L-A-N-G-V-P-P-L-I-E-N-T-N-S-E-D-K-P-T-V-L-A-L-R-E-I-A-A-R-K-I-D-S-K-M-I-D-E-I-E-K-A-E-R-E-R-T-E-R-E-A-M-E-W-A-A-A-E-V-V-A-D-E-D-M-S-K-S-D-D


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-A-V-V-W-W-Q-S-L-L-L-V-M-L-G-G-A-F-G-S-G-L-R-F-V-I-G-S-C-L-L-Q-R-F-G-A-G-F-P-W-G-T-L-A-V-N-L-I-G-S-F-V-A-G-F-L-L-I-W-L-D-K-R-G-S-A-G-W-S-W-R-M-L-L-I-V-G-L-I-G-G-L-T-T-F-S-S-L-M-M-E-C-L-V-F-V-R-S-D-R-S-L-M-V-G-L-Y-L-C-I-T-L-L-F-G-L-L-F-V-F-L-G-A-R-L-G-A-F-V-C-D-D-Q-R-V-L-E-I-D-R-T-A


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-C-I-E-F-E-G-T-V-S-E-T-L-P-N-T-T-F-R-I-K-L-E-N-G-H-E-V-T-A-H-I-S-G-R-M-R-K-N-Y-I-R-I-L-T-G-D-R-V-K-I-E-M-T-A-Y-D-L-T-K-G-R-I-I-Y-R-M-K


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-Q-K-T-V-H-D-Q-D-N-A-L-L-L-E-T-G-N-T-K-V-A-P-P-P-R-Y-Q-V-L-L-L-N-D-D-Y-T-P-M-D-F-V-I-V-V-L-Q-Q-F-F-A-M-D-L-K-K-A-T-Q-V-M-L-H-V-H-T-R-G-C-G-V-C-G-F-Y-T-R-E-V-A-E-S-K-V-A-Q-V-N-E-F-S-R-I-H-Q-H-P-L-L-C-T-M-K-Q-A


### FUNCTION General  is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-L-E-H-E-L-I-V-T-N-K-L-G-L-H-A-R-A-T-A-K-L-V-Q-T-M-S-K-F-Q-S-N-T-T-L-S-T-K-G-R-E-V-N-A-K-S-I-M-G-V-M-L-L-A-A-S-Q-G-T-V-I-R-V-R-I-D-G-E-D-E-H-T-A-M-Q-A-L-S-E-L-F-E-N-R-F-N-E-D-T


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-R-G-I-N-K-V-I-L-V-G-N-L-G-N-D-P-D-I-K-Y-T-Q-G-G-M-T-I-T-T-I-S-L-A-T-T-S-V-R-K-D-K-E-G-N-T-Q-E-R-T-E-W-H-R-V-K-F-F-G-K-L-G-E-I-A-G-E-Y-L-R-K-G-S-Q-C-Y-I-E-G-S-I-R-Y-D-K-F-T-G-Q-D-G-Q-E-R-Y-V-T-E-I-V-A-D-E-M-Q-M-L-G-G-R-S-D-G-G-G-M-G-G-G-G-E-R-P-Q-R-Q-T-S-Q-R-Q-D-Y-A-P-R-R-Q-A-R-Q-P-S-Q-S-P-Q-S-S-P-P-P-M-D-D-F-A-D-D-D-I-P-F


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-R-N-W-R-W-L-L-L-V-L-A-A-L-L-S-W-L-Q-H-R-F-W-F-G-P-G-N-S-G-E-V-R-M-L-Q-V-Q-I-V-Q-Q-H-Q-E-N-E-R-L-R-Q-R-N-A-S-L-A-A-E-V-K-N-L-K-D-G-D-A-A-I-E-E-R-A-R-S-E-L-G-M-I-K-P-G-E-I-F-Y-R-V-V-E-D-I-P-T-P-L-P-N-D-T-S-A-D-H-G-V-D-L-A-Q-P-R-R-E-K-R


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-S-E-L-P-V-V-E-S-D-R-R-L-I-W-I-D-L-E-M-T-G-L-D-T-H-R-D-S-I-I-E-I-A-T-V-V-T-D-A-Q-L-N-V-L-A-E-G-P-E-F-A-I-S-H-P-L-Q-M-L-E-A-M-D-E-W-N-R-N-Q-H-R-H-S-G-L-W-Q-R-V-L-N-S-E-I-Q-H-A-Q-A-E-A-S-T-I-A-F-L-Q-Q-W-V-K-T-G-A-S-P-M-C-G-N-S-I-C-Q-D-R-R-F-L-H-R-Q-M-P-C-L-E-R-Y-F-H-Y-R-N-L-D-V-S-T-L-K-E-L-A-G-C-W-A-P-S-I-L-D-G-V-V-K-T-S-S-H-T-A-L-S-D-I-Y-D-S-I-A-E-L-R-H-Y-R-K-S-M-G-T-F-A-G-L-P-V-V


### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions ### SEQUENCE -M-N-K-T-E-L-I-D-G-V-A-A-A-A-N-L-S-K-V-E-A-G-R-A-I-D-A-V-V-N-E-I-T-E-A-L-K-K-G-D-S-V-T-L-V-G-F-G-T-F-Q-V-R-P-R-A-E-R-P-G-R-N-P-K-S-G-E-L-I-M-I-A-A-S-N-N-P-S-F-K-P-G-K-A-L-K-D-A-V-K-C-S-A-G


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-Q-S-V-V-K-I-K-K-K-V-K-R-V-I-T-D-G-V-A-H-I-S-A-S-F-N-N-T-I-V-T-I-T-D-R-Q-G-N-S-L-F-W-C-T-S-G-A-S-G-F-R-G-S-R-K-C-T-P-F-A-A-Q-V-A-A-E-K-A-G-R-A-V-L-D-Y-G-M-K-S-L-E-V-R-I-N-G-P-G-P-G-R-E-S-A-V-R-S-L-N-N-V-G-Y-K-I-T-N-I-I-D-V-T-P-I-P-H-N-G-C-R-P-P-K-K-R-R-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-L-A-I-Q-K-H-V-W-I-G-L-Q-S-I-Y-G-I-G-R-T-R-S-R-K-V-C-D-A-A-N-V-A-I-Y-T-K-I-R-D-L-S-E-P-E-I-E-R-L-R-V-E-V-G-K-Y-V-I-E-G-D-L-R-R-E-V-G-M-A-I-K-R-L-M-D-L-N-C-Y-R-G-L-R-H-R-R-G-L-P-L-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-K-A-I-K-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-I-M-S-L-R-L-N-D-L-K-P-A-L-G-A-S-S-C-R-A-R-V-G-R-G-I-G-S-G-L-G-K-T-A-G-R-G-H-K-G-S-F-A-R-K-G-G-G-K-I-K-P-G-F-E-G-G-Q-T-P-M-Q-R-R-L-P-K-I-G-F-R-S-R-S-V-A-N-T-A-E-V-L-S-Y-K-L-D-N-L-E-P-G-E-I-D-F-A-S-L-R-L-A-K-L-V-P-S-T-A-K-K-A-K-I-V-K-K-G-R-L-T-K-V-F-V-L-K-G-I-E-S-T-A-G-A-R-A-M-I-E-T-T-G-G-S-F-Q-E


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-E-E-R-S-Q-R-N-R-D-R-S-R-E-E-K-I-D-D-G-M-I-E-K-L-V-A-V-N-R-V-S-K-T-V-K-G-G-R-Q-F-T-F-T-A-L-T-I-V-G-N-G-E-G-S-V-G-F-G-Y-G-K-A-R-E-V-P-V-A-I-Q-K-S-M-E-Y-A-R-K-T-M-A-N-V-S-L-N-N-G-T-L-W-H-P-V-K-A-N-H-G-A-A-C-V-F-M-K-P-A-S-E-G-T-G-V-I-A-G-G-A-M-R-A-V-L-E-A-V-G-V-K-D-V-L-A-K-A-I-G-S-R-N-P-I-N-L-V-R-A-T-L-K-G-L-E-D-M-Q-S-P-T-H-I-A-L-K-R-G-K-N-V-R-G-F-S-H-G-S


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-I-G-K-N-V-A-R-L-R-R-A-K-S-T-R-V-H-I-R-K-L-G-V-P-R-L-S-V-L-R-T-G-R-H-L-Y-A-Q-I-F-T-A-D-G-S-K-V-I-A-A-A-N-T-L-Q-S-Q-V-K-D-G-L-K-N-G-K-N-S-L-A-A-T-K-V-G-K-L-I-A-E-R-A-K-A-V-G-V-D-R-I-A-F-D-R-S-G-Y-L-Y-H-G-R-I-K-I-L-A-D-A-A-R-D-A-G-L-K-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-K-P-I-S-V-P-K-G-V-E-V-S-V-R-S-D-M-L-T-V-K-G-V-K-G-V-L-T-F-P-K-S-D-N-V-N-V-V-V-D-G-D-I-L-T-L-S-A-N-D-P-S-H-V-S-L-A-G-T-V-R-A-I-L-S-N-M-I-K-G-V-S-I-G-F-E-R-K-L-E-L-V-G-V-G-Y-R-A-S-M-Q-G-E-N-L-N-L-S-L-G-F-S-H-P-L-V-F-V-P-P-E-G-I-T-L-L-T-P-S-Q-T-E-V-V-V-Q-G-I-D-K-Q-R-V-G-E-V-A-A-K-I-R-S-F-R-P-P-E-P-Y-K-G-K-G-L-K-Y-A-A-E-A-I-M-R-K-E-A-K-K-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-T-D-P-I-A-D-M-L-V-R-I-N-N-A-A-S-V-G-K-P-N-V-R-F-P-F-S-R-V-K-L-A-I-A-L-V-L-K-H-E-G-Y-I-F-D-A-K-V-I-Q-G-D-N-S-K-S-D-I-E-I-V-L-K-Y-F-E-G-R-P-V-I-R-I-L-K-R-V-S-R-S-G-L-R-K-Y-C-G-K-A-E-L-P-K-V-L-G-G-L-G-I-S-I-I-S-T-S-K-G-I-M-I-D-S-K-A-R-E-S-G-V-G-G-E-V-L-C-F-V-A


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-I-S-M-I-N-R-D-L-K-R-K-R-L-A-K-K-F-A-D-K-R-L-S-L-K-K-V-I-S-S-D-A-S-S-Y-E-E-K-I-E-A-S-C-K-L-Q-K-L-P-R-D-S-S-P-T-R-L-R-N-R-C-E-I-S-G-R-P-R-G-V-Y-C-K-F-G-L-G-R-N-K-L-R-E-A-A-M-R-G-D-V-P-G-L-R-K-A-S-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-R-L-E-N-M-Y-K-K-E-V-V-P-A-L-I-K-R-F-G-Y-S-N-P-M-A-V-P-R-L-V-K-I-T-L-N-M-G-V-G-E-A-A-T-N-K-K-V-L-E-N-A-V-A-D-M-A-K-I-S-G-Q-R-P-I-V-T-K-S-R-I-S-V-A-S-F-K-I-R-N-G-W-P-I-G-C-K-T-T-L-R-R-S-K-M-Y-E-F-L-D-R-L-I-N-I-S-L-P-C-V-R-D-F-R-G-I-P-P-R-S-F-D-G-R-G-N-F-N-M-G-V-K-E-Q-V-V-F-P-E-I-D-F-D-A-V-D-A-I-R-G-M-D-I-A-I-T-T-T-A-N-S-D-A-E-A-K-A-L-L-D-A-F-N-F-P-F-R-N


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-S-R-I-K-K-G-D-Q-V-I-V-I-A-G-K-D-K-G-K-Q-G-E-I-I-R-I-D-G-H-R-V-V-V-S-N-V-N-I-V-K-R-H-T-K-P-N-P-Q-R-S-I-S-G-G-L-I-D-R-E-A-P-I-H-V-S-N-I-Q-V-L-N-P-M-T-G-K-G-D-R-V-G-F-K-I-L-D-D-G-C-K-L-R-I-F-R-S-T-G-E-V-I-G-A


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-Y-L-G-V-A-D-N-S-G-A-K-E-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-S-I-G-D-I-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-E-V-Y-D-A-V-V-V-R-T-R-S-G-V-R-R-P-D-G-S-L-I-R-F-D-G-N-A-A-V-L-L-N-N-K-Q-E-P-I-G-T-R-V-F-G-P-V-T-R-E-L-R-S-E-K-L-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-M-N-D-H-N-E-R-K-P-L-R-T-I-K-G-R-V-I-S-N-K-M-Q-K-T-V-T-V-L-V-E-R-Q-I-K-H-A-L-Y-G-K-Y-I-K-R-S-T-K-L-H-A-H-D-A-D-D-L-C-N-E-G-D-V-V-L-M-T-E-V-A-P-I-S-K-T-K-N-W-R-V-V-E-I-V-A-R-S-D


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-Y-R-K-M-H-K-G-R-N-C-G-L-S-W-N-A-N-V-V-S-F-G-Q-Y-G-L-R-A-T-A-H-G-Q-L-T-A-R-Q-I-E-A-A-R-R-S-I-S-R-Y-V-K-R-G-G-K-L-L-I-R-V-F-P-D-K-P-I-T-K-K-P-I-E-V-R-M-G-S-G-K-G-N-V-E-Y-W-V-A-Q-I-Q-P-G-R-M-I-Y-E-I-E-G-V-S-E-D-V-A-R-E-A-F-R-L-A-A-S-K-L-S-V-T-T-A-F-V-V-R-T-V-R


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-T-A-I-L-R-G-A-R-I-S-P-Q-K-A-R-L-V-A-A-Q-V-R-G-L-S-A-E-S-A-V-N-I-L-R-F-S-S-K-K-A-A-C-L-I-K-K-V-V-E-S-A-I-A-N-A-E-N-N-H-G-S-N-I-D-A-L-K-I-N-T-I-I-V-D-E-G-R-M-L-K-R-F-M-A-R-A-K-G-R-S-S-R-I-V-K-R-S-S-H-I-T-V-V-V-G-P-A-K


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-T-K-K-G-P-F-F-D-H-H-L-I-K-K-V-E-S-A-A-G-S-K-R-P-I-K-T-C-S-R-R-S-V-I-L-P-Q-M-V-G-H-T-I-A-I-H-N-G-K-N-Y-Y-P-V-V-I-N-E-N-M-V-G-H-K-L-G-E-F-S-I-T-R-V-F-K-G-H-G-G-D-K-K-S-G-K


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-S-S-C-E-K-I-F-G-V-L-R-S-P-R-V-S-E-K-S-S-R-L-Q-E-I-S-N-V-Y-V-F-E-V-S-S-D-A-T-K-V-D-V-K-N-A-V-E-R-L-F-D-V-K-V-G-V-V-R-V-L-N-V-K-G-K-S-K-S-F-R-N-R-G-G-S-R-S-G-W-R-K-A-Y-V-R-L-I-D-G-Q-S-I-D-V-A-A-N-V


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-I-T-F-T-I-F-A-Q-S-L-A-F-A-A-L-I-W-I-V-A-T-K-I-W-P-P-L-I-K-V-I-E-E-R-Q-Q-K-I-A-E-G-L-A-A-A-D-L-G-Q-K-E-L-A-Q-A-Q-E-E-I-K-K-T-L-K-N-A-R-E-K-A-N-E-I-I-E-Q-A-H-A-R-A-H-Q-I-I-E-A-A-K-A-E-A-I-T-E-T-N-R-Q-Q-N-L-A-Q-V-E-I-E-A-A-A-K-R-A-R-E-E-L-R-K-H-V-S-I-L-A-V-N-G-A-E-K-L-L-K-R-E-I-D-V-N-T-H-K-M-L-L-D-E-L-A-A-E-I


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-Q-A-L-T-L-A-R-P-Y-A-R-A-A-F-A-I-A-C-E-K-G-K-C-M-Q-W-S-Q-A-L-T-F-S-A-Q-V-A-N-N-P-I-A-A-A-L-L-C-H-P-Q-I-D-H-E-Q-A-A-A-L-L-S-P-E-G-A-D-P-A-Y-V-R-F-L-E-V-I-A-E-A-H-R-L-D-V-L-L-Q-V-A-G-L-Y-E-K-L-R-A-E-A-E-H-V-I-K-A-K-I-T-S-A-I-E-L-A-P-N-E-L-N-N-I-V-T-A-L-K-K-R-F-D-C-E-I-E-V-T-T-G-V-D-H-S-L-I-G-G-A-V-I-D-T-G-N-V-V-I-D-G-S-I-K-S-K-L-T-R-L-Q-A-S-L-T-H


### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-L-Y-L-A-S-R-S-L-C-R-R-Q-L-L-Q-R-L-D-I-P-F-Q-V-I-D-L-E-I-P-E-V-R-R-E-D-E-L-P-Q-D-Y-V-R-R-V-A-Q-E-K-A-Q-V-G-L-A-R-V-R-D-A-F-A-P-K-V-L-G-A-D-T-E-V-V-L-D-G-R-V-F-G-K-P-A-D-L-V-E-A-A-A-M-L-A-A-L-S-G-R-T-H-Q-V-M-T-A-V-S-L-V-A-A-G-G-V-A-A-Q-V-L-V-V-S-E-V-S-F-A-L-L-S-Q-G-Q-I-A-R-Y-V-D-S-G-E-P-M-G-K-A-G-A-Y-A-I-Q-G-R-G-E-C-F-V-S-R-L-V-G-S-Y-S-G-V-M-G-L-P-L-Q-Q-T-A-Q-L-L-T-T-F-E-E-S


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-R-A-P-M-T-L-K-G-V-R-R-L-R-D-E-L-E-H-L-K-S-V-K-R-P-E-I-I-N-A-I-A-E-A-R-A-H-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-Q-Q-S-F-I-E-G-R-I-K-Q-L-E-G-E-L-S-H-A-E-V-I-D-V-A-K-L-N-A-G-T-K-I-V-F-G-A-T-V-T-L-V-D-L-E-T-D-E-E-S-R-Y-Q-I-V-G-D-L-E-A-D-I-K-Q-G-L-V-A-I-S-S-P-V-A-R-A-L-I-G-K-Q-E-G-D-T-I-V-I-E-A-P-A-G-R-R-E-Y-E-V-V-A-V-E-Y-I-S


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-N-Q-I-K-Q-D-A-Q-D-R-M-T-K-S-I-D-A-L-R-N-S-L-A-S-V-R-T-G-R-A-S-P-S-L-L-D-G-I-K-I-K-A-Y-G-T-D-T-P-L-N-Q-V-A-S-I-S-V-S-E-G-R-S-L-V-I-T-V-F-D-K-N-M-S-K-D-V-E-K-A-I-Y-A-S-D-L-G-L-T-P-T-V-V-G-T-L-I-R-L-N-L-P-P-L-T-E-E-R-R-K-E-L-T-K-V-V-H-S-E-G-E-D-T-K-V-A-I-R-N-I-R-R-D-A-N-Q-Q-I-K-D-M-L-K-S-K-E-I-T-E-D-E-V-R-Q-G-E-E-D-I-Q-K-L-T-D-K-A-I-K-S-V-D-E-V-V-K-S-K-E-Q-E-L-M-T-V


### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-H-K-A-I-M-H-P-L-I-L-L-L-K-I-Y-K-R-L-I-S-P-L-L-G-P-H-C-R-F-E-P-S-C-S-E-Y-A-M-G-A-I-A-R-F-G-T-L-R-G-I-W-L-A-A-R-R-L-A-R-C-Q-P-L-Q-P-G-G-Y-D-P-V-P-D-N-I-S-T-Q-V-N-P-P-S-H-R-C-T-G-H-H-Q


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-S-N-A-S-G-G-G-P-R-P-R-R-R-D-G-V-D-P-A-L-R-S-R-A-R-R-R-A-L-Q-A-V-Y-A-W-Q-I-S-G-G-V-A-K-Q-V-I-A-H-F-A-H-E-Q-A-Y-E-V-A-D-L-A-Y-F-E-D-L-V-E-G-V-L-T-H-C-A-E-L-D-E-K-L-T-P-Y-L-D-R-T-I-E-E-V-D-A-I-E-R-A-V-L-R-L-G-A-Y-E-L-L-Y-R-Q-D-V-P-Y-R-V-V-I-N-E-A-I-M-T-A-K-R-F-G-S-K-Y-G-H-T-Y-V-N-G-V-L-D-R-A-A-L-A-L-R-K-V-E-V-L-G


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Y-C-L-F-C-Q-H-T-Y-T-R-V-I-D-S-R-V-S-E-D-G-A-T-I-R-R-R-R-E-C-E-A-C-G-E-R-F-S-T-L-E-T-I-E-L-K-L-P-V-I-I-K-K-D-G-G-R-E-A-F-D-G-R-K-L-R-T-S-F-D-R-A-L-Q-K-R-P-V-A-E-E-C-I-E-M-A-L-R-A-V-I-H-R-L-R-M-A-G-E-R-E-V-P-S-I-V-V-G-E-Y-V-M-A-E-L-R-K-L-D-H-V-G-Y-V-R-F-A-S-V-Y-R-S-F-Q-D-V-A-D-F-R-E-E-I-E-K-L-E-S-E-L-L-V-S-R-E-Q-L-P-L-L-E-A-A-M-E-S-M-G-H-P-S-V-D-Q-G-G-K-H-G-V


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-R-G-P-I-F-L-N-V-G-I-S-Y-G-L-P-R-T-K-L-P-A-A-V-S-F-R-K-W-V-A-A-T-L-Q-G-R-I-R-K-A-D-L-A-I-R-I-V-D-E-K-E-G-R-A-L-N-Y-H-Y-R-N-K-D-Y-A-T-N-V-L-S-F-P-A-Q-L-P-E-P-L-P-K-A-L-K-I-P-L-L-G-D-I-V-M-C-A-P-V-I-A-R-E-A-A-E-Q-G-K-S-L-S-A-H-Y-A-H-L-T-V-H-G-T-L-H-L-L-G-W-N-H-E-D-H-Q-E-A-D-A-M-E-Q-L-E-R-E-I-L-A-N-L-G-I-S-D-P-Y-L-E-E-Y


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-E-M-V-E-R-L-F-D-E-V-G-L-N-K-R-E-A-K-E-F-V-D-T-F-F-D-L-L-R-D-A-L-E-Q-G-R-Q-I-K-L-S-G-F-G-N-F-E-L-R-C-K-N-Q-R-P-G-R-N-P-K-T-G-E-E-I-P-I-S-A-R-T-V-V-T-F-R-S-G-Q-K-L-K-E-R-V-D-A-Y-V-G-S-R-Q


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-Q-A-R-R-R-H-K-K-I-L-S-L-A-K-G-Y-Y-N-A-R-R-K-V-F-R-V-A-K-Q-A-V-I-K-A-Q-Q-Y-A-Y-I-G-R-K-Q-K-K-R-N-F-R-S-L-W-I-V-R-I-N-A-A-A-R-I-N-G-L-S-Y-S-R-F-M-N-G-L-L-K-C-G-I-T-L-D-R-K-V-L-A-D-I-A-V-H-D-P-A-G-F-T-A-L-A-E-K-A-K-S-I-L-A-A


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-G-D-C-N-I-S-T-S-D-N-K-Q-N-R-K-N-H-E-I-R-V-P-R-V-R-V-I-G-S-D-G-E-M-V-G-V-L-S-R-D-E-A-L-A-M-A-E-K-E-G-L-D-L-V-E-I-Q-P-Q-A-D-P-P-V-C-K-V-M-N-F-G-K-F-K-F-E-Q-Q-K-K-A-N-E-A-K-K-K-T-K-Q-V-E-I-K-E-L-K-F-R-P-V-T-D-E-G-D-Y-Q-I-K-L-R-N-M-R-R-F-L-E-E-G-D-K-V-K-I-N-I-R-F-R-G-R-E-M-S-H-Q-E-L-G-R-Q-M-A-T-R-I-E-M-D-L-G-D-D-V-V-I-E-S-R-P-R-L-E-G-R-Q-M-V-M-M-V-A-P-R-K-K-S


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-P-K-H-S-P-P-D-T-S-P-V-A-R-F-E-Q-S-L-Q-E-L-E-Q-L-V-Q-N-M-E-T-G-A-L-S-L-E-Q-S-L-G-A-Y-E-R-G-I-A-L-Y-R-E-C-H-Q-A-L-E-Q-A-Q-L-R-V-R-L-L-S-D-P-M-H-P-D-D-G-E-P-F-D-P-S-L-V-S-T-S-Q


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-S-F-S-L-L-H-W-L-V-V-L-V-I-V-L-L-V-F-G-T-K-R-L-A-N-G-A-K-D-I-G-S-A-I-K-E-F-K-K-S-L-R-E-D-D-K-P-T-D-Q-L-G-S-T-S-Q-S-T-A-S-G-P-Q-Q-D-H-G-K-H


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-I-G-F-S-E-L-L-L-I-A-V-V-A-L-V-V-L-G-P-E-R-L-P-K-A-A-R-F-A-G-L-L-V-R-R-A-R-T-Q-W-E-S-I-K-Q-E-L-E-R-E-L-E-A-E-A-L-K-R-N-L-E-N-A-Q-Q-V-I-H-D-A-Q-A-Q-L-Q-S-N-Q-Q-D-M-N-I-Q-N-S-I-S-I-L-H-E-Q-T-K-R-D-I-H-P-D-R-N-T-N-T-L-E-L-G-T-A-V-H-H-V-H-V-T-S-P-P-P-S-T-S-T-H-G-N-N-G-Q-E-K-S-Q


### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-P-D-G-Y-R-P-N-V-G-I-V-L-M-C-R-D-G-Q-V-F-W-G-R-R-V-R-L-D-G-W-Q-F-P-Q-G-G-M-H-S-D-E-T-P-V-E-A-M-Y-R-E-L-N-E-E-T-G-L-L-P-E-H-V-Q-L-L-G-A-T-P-G-W-L-R-Y-R-L-P-S-Q-A-V-R-C-N-R-S-Q-M-C-I-G-Q-K-Q-V-W-F-L-L-Q-L-I-G-D-E-S-H-V-Q-L-D-Q-S-E-N-P-E-F-D-H-W-R-W-V-S-F-W-Y-P-I-E-H-V-V-M-F-K-R-G-V-Y-A-R-A-L-C-Q-L-A-S-L-A-Q-Q-V-V-G-L-E-V-G-T-M-P-Q-Y-V-Q-D-I-C-L-L-N-V-G-Y-K-H-L-P-N-W-V-S-R-Y


### FUNCTION Required for disulfide bond formation in some periplasmic proteins Acts by oxidizing the DsbA protein ### SEQUENCE -M-N-A-L-Q-W-S-F-R-A-Q-C-L-T-G-F-L-F-C-T-G-L-L-A-Y-A-I-F-L-Q-L-H-Q-G-L-E-P-C-P-L-C-I-F-Q-R-I-A-F-A-V-L-G-I-L-F-L-I-A-G-L-Y-N-S-S-N-V-Y-T-R-K-A-Y-G-L-L-I-F-L-T-A-A-I-G-T-G-I-A-G-R-H-V-W-V-Q-L-M-P-H-N-T-I-S-S-C-G-S-P-L-S-F-L-S-E-T-M-G-P-F-E-V-F-R-T-V-L-T-G-T-S-D-C-G-N-I-D-W-R-F-L-G-L-S-M-P-M-W-S-M-F-W-F-V-A-L-A-L-L-G-L-L-V-G-F-K-A-E-R-R-K-P-L-F-S


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-M-K-C-L-L-I-A-T-G-E-R-V-P-T-W-V-A-Q-G-F-A-E-Y-H-K-R-L-S-Y-W-L-P-L-E-L-V-E-I-E-P-S-L-R-G-K-N-H-D-P-Q-Q-A-I-E-D-E-G-R-R-V-M-A-A-L-P-K-Q-P-Y-A-V-T-L-D-V-K-G-K-S-L-N-S-E-Q-L-A-K-R-M-E-H-W-R-G-L-G-R-N-L-V-F-L-I-G-G-P-E-G-H-S-Q-E-V-L-N-I-S-N-E-R-W-S-L-G-P-L-T-L-P-H-M-L-V-R-L-I-V-V-E-Q-L-Y-R-A-A-T-I-L-T-N-H-P-Y-H-R-G-K


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-P-K-K-S-F-Q-R-A-E-R-I-S-V-Q-I-H-R-D-L-G-A-L-V-Q-A-A-V-R-D-H-G-L-P-S-M-S-V-S-D-V-E-V-T-R-D-M-A-H-A-K-V-F-V-T-A-L-Q-A-E-R-S-F-E-A-V-A-G-L-K-A-L-A-R-E-L-R-M-Q-L-A-H-T-M-R-L-R-F-V-P-E-L-H-F-H-Y-D-D-S-L-D-R-G-E-R-I-N-T-L-L-R-D-L-I-P-P-A-D-A-E-K-D-E-C-G


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-D-K-G-I-E-I-V-N-L-L-A-P-K-V-E-T-L-G-F-E-L-L-G-A-E-Y-L-L-V-P-S-G-A-I-L-R-L-Y-I-D-T-P-F-A-M-Q-P-E-C-M-V-S-I-D-D-C-E-R-V-S-R-E-V-S-A-Y-L-D-V-E-E-P-I-S-G-N-Y-T-L-E-V-S-S-P-G-L-D-R-R-L-F-T-L-E-Q-F-A-R-H-Y-N-Q-F-V-K-V-G-L-K-L-P-Q-H-G-S-R-R-L-Q-G-K-I-V-R-V-E-Q-V-D-G-F-V-V-L-L-V-N-G-V-E-L-A-V-D-F-N-N-I-D-K-A-R-I-V-P-D-W-S-A-L-G-L-A-P-L-E-K-S-K-P-D-T-K-K-T-S-Q-G-N-K-K-P-S-N-E-S-A-A-R-Q-A-V-R-G-V-I-R


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-D-I-P-G-D-L-K-F-L-K-S-H-E-W-V-R-I-E-D-N-N-R-A-I-V-G-I-S-D-H-A-Q-N-L-L-G-D-L-V-Y-V-E-L-P-N-I-G-D-H-L-D-A-G-T-T-A-A-V-I-E-S-V-K-A-A-S-D-I-Y-S-P-V-T-G-K-V-I-E-V-N-T-T-L-S-D-K-P-E-T-I-N-E-D-P-Y-G-E-G-W-I-M-V-I-E-M-Q-A-P-E-E-I-S-D-L-L-S-P-D-D-Y-T-K-V-L-E-S-D-E-H


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-S-A-A-V-Q-P-L-Q-I-K-I-L-D-P-R-L-G-T-V-W-L-L-P-T-Y-A-T-E-A-S-A-G-L-D-L-R-A-A-L-D-A-P-M-T-L-V-P-G-D-A-E-L-L-S-T-G-V-A-I-H-L-V-D-P-S-L-C-A-V-V-L-P-R-S-G-L-G-H-R-H-G-I-V-L-G-N-G-T-G-L-I-D-S-D-Y-Q-G-P-L-L-V-S-V-W-N-R-G-R-E-A-F-T-I-E-P-G-D-R-I-A-Q-L-V-V-L-P-I-V-R-V-V-L-Q-V-V-D-T-F-V-E-S-G-R-G-A-G-G-F-G-H-T-G-V-R


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-S-K-L-N-K-S-I-I-A-E-F-E-S-A-Q-I-T-R-Q-V-P-Q-F-S-Q-G-D-T-I-V-V-N-V-K-V-K-E-G-N-R-E-R-L-Q-A-Y-E-G-V-V-I-A-T-K-N-A-G-L-N-S-A-F-T-V-R-K-I-S-H-G-Y-G-V-E-R-V-F-Q-T-H-S-P-I-I-E-S-I-E-I-K-R-R-G-K-V-R-A-A-K-L-Y-Y-L-R-G-L-E-G-K-A-A-R-I-K-E-D-L-A-A-T-A-Q-E-K-L-A-R-K-T-V-T-A-K-A-G


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-D-N-E-R-R-I-L-L-G-R-V-V-G-G-F-G-L-R-G-E-I-K-I-E-S-W-T-E-P-R-D-A-I-F-R-Y-Q-P-W-L-L-R-S-P-T-G-T-E-S-M-L-N-G-A-R-G-Y-E-T-G-K-R-L-I-A-T-F-P-G-I-N-D-R-N-A-V-E-A-I-C-G-T-E-I-Y-V-P-R-S-A-L-P-P-P-H-P-D-E-Y-Y-W-V-D-L-E-G-L-Q-V-H-T-L-E-G-V-V-L-G-S-V-S-H-L-F-S-N-G-A-N-D-V-I-V-I-H-G-E-R-E-R-L-I-P-F-V-Q-P-D-Y-V-K-S-V-D-F-E-A-E-R-I-V-V-D-W-D-P-E-F


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-T-I-E-S-F-D-Q-F-V-V-L-L-R-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-N-V-R-V-G-P-G-G-G-Y-V-Q-S-G-S-D-T-L-Q-I-N-D-D-E-V-E


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-F-I-R-E-F-K-E-F-V-M-R-G-N-V-I-D-L-A-V-A-V-V-I-G-A-A-F-G-K-I-V-T-A-L-V-D-K-I-I-S-P-L-I-G-V-M-V-G-G-I-D-F-S-K-L-S-L-T-L-K-A-A-T-V-D-A-A-G-K-E-V-P-A-V-V-I-G-Y-G-D-F-L-N-T-I-L-Q-F-I-I-I-A-F-A-I-F-I-I-V-K-M-I-N-K-V-I-N-K-Q-P-L-P-P-E-T-P-S-E-D-V-L-L-L-R-E-I-R-D-S-L-K-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-L-L-I-K-D-V-K-A-L-G-K-A-G-E-I-K-E-V-K-D-G-Y-G-Q-N-F-L-I-A-K-G-F-A-K-A-A-T-N-E-V-L-R-K-Y-E-S-D-K-K-K-E-A-E-N-L-R-F-E-I-A-N-L-E-K-L-K-E-E-L-S-K-I-T-L-E-I-S-K-P-V-G-A-N-G-S-L-F-G-G-V-T-K-D-E-I-A-H-A-L-K-E-Q-S-H-I-E-I-D-K-K-S-L-E-C-D-T-L-K-S-L-G-I-H-E-V-S-V-K-L-G-H-A-I-H-A-K-F-N-I-N-I-K-A-E


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-I-I-S-A-K-F-I-T-S-L-V-K-F-D-E-N-L-S-S-N-F-S-E-V-A-F-L-G-R-S-N-V-G-K-S-S-L-I-N-S-L-C-K-Q-K-N-L-A-K-S-S-A-T-P-G-K-T-Q-L-I-N-F-F-E-V-I-C-R-R-N-E-E-K-F-N-I-N-F-I-D-L-P-G-F-G-Y-A-K-V-S-K-N-L-K-E-I-W-N-Q-N-L-D-E-F-L-K-L-R-T-S-I-K-L-F-I-H-L-I-D-S-R-H-T-H-L-E-I-D-V-N-L-N-D-Y-L-K-R-F-L-R-P-D-Q-K-I-L-K-V-F-T-K-C-D-K-L-N-Q-S-E-K-A-K-L-K-N-E-F-K-D-S-I-L-V-S-N-L-N-K-F-G-L-D-S-L-E-D-I-I-I-N-Q-T-L-G-L-D-K


### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-K-N-I-V-L-G-G-G-C-F-W-C-V-E-A-V-F-E-R-L-K-G-V-I-N-T-E-V-G-Y-S-G-G-K-P-N-P-S-Y-E-S-V-C-N-G-D-G-N-I-E-V-V-K-I-N-Y-D-E-K-Q-I-S-L-L-E-I-L-T-L-F-F-K-I-H-D-P-T-S-I-D-K-Q-G-G-D-I-G-I-Q-Y-R-S-I-I-F-Y-E-N-E-E-D-K-I-L-A-Q-N-F-I-E-E-Q-Q-K-I-F-S-K-K-I-V-T-K-I-S-R-L-Q-T-Y-Y-K-A-E-N-Y-H-Q-H-Y-F-I-N-N-P-D-Q-G-Y-C-Q-A-V-I-A-P-K-L-Q-K-I-Q-S-D


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-A-L-A-L-D-V-G-L-K-R-I-G-V-A-L-C-I-D-K-K-I-A-L-P-L-D-A-V-L-R-K-N-R-N-Q-A-A-N-E-I-K-N-L-L-K-I-H-E-I-S-L-L-I-V-G-I-P-K-G-G-S-S-E-E-E-M-T-R-R-I-K-H-F-V-S-L-L-E-F-D-K-E-I-C-F-V-D-E-S-G-T-S-K-E-A-L-G-Y-G-V-A-N-T-R-K-K-D-G-K-L-D-S-L-S-A-F-I-M-I-K-D-Y-F-A-L


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-I-V-E-S-L-I-E-L-C-E-E-N-A-L-N-N-K-A-Y-N-V-Q-E-I-Y-V-K-I-G-R-L-S-G-I-E-V-D-L-F-K-R-C-F-E-T-F-K-E-N-S-N-I-C-K-N-A-K-L-F-I-E-L-A-P-L-E-I-L-C-L-K-C-D-Q-T-S-I-L-E-E-N-V-F-K-C-P-K-C-Q-S-I-E-Y-K-I-I-Q-G-E-D-L-H-L-M-R-L-V-M-K


### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-E-N-E-K-N-Y-R-P-N-V-A-A-I-V-L-S-S-S-Y-P-F-E-C-K-I-F-I-A-R-R-S-D-M-D-N-I-W-Q-F-P-Q-G-G-I-D-K-G-E-S-V-K-N-A-L-F-R-E-L-K-E-E-I-G-T-D-E-V-E-I-I-A-E-Y-P-E-W-L-S-Y-D-F-P-S-K-I-V-K-K-M-Y-P-Y-D-G-Q-I-Q-K-Y-F-L-V-R-L-K-H-G-A-T-I-N-I-N-T-K-H-P-E-F-D-D-Y-Q-F-V-S-V-K-Q-I-F-E-M-I-N-H-F-K-K-N-I-Y-V-R-V-I-K-Y-F-E-E-K-G-Y-I


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-S-F-G-E-I-I-V-I-L-V-V-A-I-L-V-L-G-P-D-K-L-P-E-A-I-V-Q-I-A-K-I-L-K-A-V-K-R-N-I-D-D-A-K-S-S-I-E-K-E-I-R-I-N-D-L-K-E-E-A-K-K-Y-K-D-E-F-S-S-T-N-E-N-I-R-K-K-L-S-F-E-E-F-D-D-L-K-R-D-I-L-D-K-T-K-V-D-L-T-F-D-S-R-D-D-K-V-K-N-N-L-S-G-Q-N-L-N-T-E-E-K-P-N-L-S-K-L-E-T-Q-D-K-N-G-K-I-N-V


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-Y-S-M-G-D-L-K-K-G-L-K-I-E-I-D-G-I-P-F-K-I-V-E-Y-Q-H-V-K-P-G-K-G-P-A-F-V-R-I-K-I-K-S-F-I-D-G-K-V-L-E-K-T-F-H-A-G-D-K-C-E-A-P-N-L-E-D-K-T-M-Q-Y-L-Y-D-D-G-E-N-C-Q-F-M-D-T-Q-T-Y-E-Q-V-A-I-S-D-D-D-V-G-E-A-K-K-W-M-L-D-G-M-M-V-D-V-L-F-H-N-G-K-A-I-G-V-E-V-P-Q-V-V-E-L-K-I-I-E-T-A-P-N-F-K-G-D-T-Q-G-S-N-K-K-P-A-T-L-E-T-G-A-V-V-Q-I-P-F-H-V-L-E-G-E-V-I-R-V-D-T-V-R-G-E-Y-I-E-R-A-N-K


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-N-T-L-L-V-V-G-F-G-G-F-I-G-A-I-L-R-M-L-S-I-N-L-V-N-K-F-F-P-Y-S-I-S-F-G-T-L-F-V-N-V-L-G-S-F-I-I-G-L-L-F-S-Y-A-Q-N-K-G-L-S-P-L-L-K-S-F-I-S-T-G-F-L-G-A-F-T-T-F-S-T-F-S-Y-Q-N-L-L-L-L-Q-S-G-N-Y-L-H-F-A-L-N-I-I-L-N-V-F-L-C-L-F-A-A-W-L-G-F-L-I-F-K


### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-L-I-L-A-S-S-S-I-S-R-A-N-L-L-K-T-A-K-I-D-F-R-Q-V-S-F-D-Y-D-E-N-L-N-K-N-I-S-P-F-L-Y-V-Q-K-I-V-L-E-K-E-R-Q-F-L-S-T-L-G-K-D-F-Q-N-Q-N-L-L-F-A-D-S-I-V-C-I-D-E-K-I-L-T-K-A-K-D-K-K-E-A-Y-E-M-L-A-L-Q-N-G-K-Y-A-S-I-L-S-A-F-L-L-V-K-P-E-K-R-V-F-S-L-S-K-T-T-L-Y-F-K-N-F-D-E-N-A-L-R-D-Y-V-E-N-D-L-Y-K-G-K-A-G-C-I-M-C-E-G-F-H-Q-N-F-I-T-Q-Q-V-G-N-L-S-T-A-L-G-L-D-I-Q-T-L-K-A-Y-L


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-R-R-K-A-P-V-R-E-V-L-P-D-P-I-Y-G-N-K-V-I-T-K-F-I-N-S-L-M-Y-D-G-K-K-S-T-A-T-T-I-M-Y-G-A-L-E-A-I-D-K-K-G-G-E-K-K-G-I-D-I-F-N-D-A-I-E-N-I-K-P-L-L-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-P-A-R-Q-Q-A-L-A-I-R-W-I-I-S-F-A-R-K-R-S-E-R-T-M-I-D-K-L-A-A-E-L-L-D-A-A-N-S-K-G-A-S-F-K-K-K-E-D-T-Y-K-M-A-E-A-N-K-A-F-A-H-Y-R-W


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-K-E-R-K-K-V-L-E-K-S-K-S-P-A-L-K-N-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-K-V-R-L-T-S-G-F-E-V-I-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-I-V-L-V-R-G-G-R-V-K-D-L-P-G-V-K-Y-H-I-V-R-G-A-L-D-T-A-G-V-A-K-R-T-V-S-R-S-K-Y-G-A-K-R-P-K-A-G-A-A-K


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-I-S-K-E-D-V-L-E-Y-I-S-N-L-S-V-L-E-L-S-E-L-V-K-E-F-E-E-K-F-G-V-S-A-A-P-V-M-V-A-G-G-A-V-A-G-G-A-V-A-A-A-E-E-K-T-E-F-D-I-V-L-T-D-G-G-A-K-K-I-E-V-I-K-I-V-R-A-L-T-G-L-G-L-K-E-A-K-D-A-V-E-Q-T-P-S-T-L-K-E-G-V-A-K-A-E-A-E-E-A-K-K-Q-L-E-E-A-G-A-K-V-E-L-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-T-R-S-E-K-V-E-I-I-A-K-L-E-E-G-F-K-A-S-E-A-I-V-V-C-N-Y-R-G-L-S-T-K-K-L-E-E-L-R-N-N-A-R-E-N-N-V-K-V-Q-I-V-K-N-T-L-A-N-I-A-L-N-N-S-G-K-T-G-L-V-L-K-D-T-N-I-Y-L-W-G-E-D-Q-L-S-V-S-K-V-A-A-K-F-E-E-N-N-D-K-F-E-I-K-T-A-H-I-E-G-E-V-A-D-V-A-K-V-K-A-L-A-K-M-P-S-R-N-E-L-L-A-M-L-L-Q-V-W-N-A-P-I-T-N-F-T-I-G-L-N-A-L-K-N-K-K-E-S-E


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-V-G-E-I-K-L-Q-I-A-A-T-K-A-N-P-S-P-P-V-G-P-A-L-G-Q-Q-G-V-N-I-M-E-F-C-K-A-F-N-E-R-T-K-D-M-A-G-F-N-I-P-V-V-I-T-V-Y-A-D-K-S-F-T-F-I-T-K-Q-P-P-A-T-D-L-I-K-K-A-A-G-I-S-K-G-T-D-N-P-L-K-N-K-V-G-K-L-T-R-A-Q-V-L-E-I-V-D-K-K-I-A-D-L-N-T-K-D-R-D-Q-A-A-K-I-I-A-G-S-A-R-S-M-G-V-E-I-V-D


### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-S-T-H-K-W-Y-A-I-Q-T-Y-A-G-S-E-M-A-V-K-R-A-I-E-N-L-V-K-D-N-G-I-E-E-Q-L-K-E-I-V-V-P-T-E-D-V-I-E-F-K-N-G-K-E-K-I-S-E-R-S-L-Y-S-G-Y-V-F-A-L-L-D-L-N-T-E-L-W-H-R-I-Q-S-L-P-K-V-G-R-F-I-G-E-S-K-K-P-T-P-L-T-E-K-D-I-N-L-I-L-E-K-V-H-N-R-A-A-P-K-P-K-I-S-F-E-E-G-E-N-V-R-I-T-E-G-P-F-A-N-F-T-A-I-V-E-E-Y-D-M-V-R-G-L-L-K-L-N-V-S-I-F-G-R-S-T-P-V-E-I-L-Y-S-Q-V-E-K-I-I


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-T-F-D-D-V-K-A-V-V-V-E-Q-L-S-I-D-A-D-A-V-K-M-E-S-K-I-I-E-D-L-G-A-D-S-L-D-V-V-E-L-I-M-A-L-E-E-K-F-E-V-E-I-P-D-S-D-A-E-K-L-I-K-I-E-D-V-V-N-Y-I-D-N-L-K-K


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-Q-I-D-E-K-L-L-S-K-L-E-K-L-S-A-L-Q-I-T-K-N-R-N-E-T-I-A-Q-L-S-E-I-V-N-F-V-E-K-L-N-E-L-D-L-D-S-Q-E-I-T-V-S-T-I-K-G-G-A-P-L-R-I-D-E-I-R-N-S-N-V-I-D-E-V-L-D-C-A-P-K-K-Q-E-H-F-F-V-V-P-K-I-I-E


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-N-I-I-E-G-K-L-N-L-D-S-N-T-K-I-A-I-I-N-A-R-F-N-H-I-I-T-D-R-L-V-E-G-A-K-D-A-F-L-R-H-G-G-K-E-E-N-L-S-L-I-L-V-P-G-A-F-E-L-P-Y-A-L-K-K-A-I-E-S-K-K-F-D-A-I-C-C-V-G-A-V-I-R-G-S-T-P-H-F-D-Y-V-S-A-E-T-T-K-G-I-A-N-V-S-L-N-H-N-I-P-V-S-F-G-V-L-T-T-D-T-I-E-Q-A-I-E-R-A-G-S-K-A-G-N-K-G-F-E-A-M-T-T-V-I-E-M-L-N-L-S-K-E-L


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-A-T-R-H-Q-V-R-Q-S-V-I-S-L-L-Y-A-F-E-L-N-S-Q-N-N-V-F-V-D-E-I-L-D-E-K-K-I-R-N-E-Q-K-N-F-T-L-N-L-Y-N-G-I-L-D-N-L-N-N-I-D-E-T-L-N-S-F-L-N-D-N-Q-I-T-A-L-G-H-V-E-R-A-I-L-R-L-G-A-Y-E-L-L-F-T-D-T-P-S-A-I-V-I-N-E-A-I-E-L-A-K-E-L-A-N-D-N-S-P-K-F-I-N-G-V-L-D-A-L-I-K-A-K-K


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-I-L-V-V-G-L-G-N-I-G-V-E-Y-E-N-T-R-H-N-V-G-F-M-L-I-D-L-L-L-K-E-S-N-F-T-N-L-T-N-S-K-F-K-G-E-L-F-K-I-G-S-S-L-L-L-L-K-P-S-T-Y-M-N-N-S-G-L-S-V-K-A-V-N-D-F-Y-K-C-E-R-M-I-V-I-H-D-D-I-D-I-N-L-G-A-L-R-F-K-K-G-G-S-S-G-G-H-N-G-L-K-S-I-D-T-L-C-G-N-D-Y-E-R-V-R-I-G-V-G-K-G-E-N-V-I-S-H-V-L-G-K-F-K-S-E-E-E-I-T-L-S-K-V-L-E-H-A-K-K-A-L-L-E-L-I-E-N-D-D-L-S-A-I-S-S-K-Y-S-L-K-A


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-L-E-G-I-V-R-E-S-I-G-R-K-A-A-K-A-L-K-R-D-G-Y-L-I-A-N-I-Y-G-K-G-L-E-N-I-N-A-A-F-K-V-N-E-F-I-K-E-V-R-K-K-T-T-L-I-F-D-V-K-V-G-S-Q-T-L-S-V-V-V-V-D-Y-Q-K-D-P-V-T-A-E-L-K-H-V-D-L-K-V-A-Q-K-G-V-I-S-K-Y-M-V-P-V-K-I-T-G-T-A-I-G-L-K-N-K-G-V-L-I-Q-S-K-R-R-L-K-V-K-C-A-A-E-N-L-P-N-F-F-E-L-D-V-S-K-L-D-V-G-D-A-L-L-V-R-D-I-V-V-P-A-G-V-T-M-I-D-A-D-R-V-A-V-V-G-V-E-K-A-R


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-Q-K-E-P-M-S-Q-F-G-Y-D-K-L-A-A-E-L-K-D-L-K-D-N-Q-R-P-A-V-V-I-E-I-D-T-A-R-S-H-G-D-L-K-E-N-A-E-Y-H-A-A-R-E-K-Q-A-L-I-E-S-R-I-A-E-L-S-D-L-L-A-R-A-Q-V-I-D-P-S-S-Y-E-H-D-S-V-K-F-G-S-S-V-V-I-M-D-L-D-T-E-K-E-S-K-Y-T-L-V-G-I-C-E-G-N-L-D-K-G-Y-I-S-I-A-S-P-I-A-K-A-M-L-G-K-K-E-G-D-D-F-K-V-R-L-P-K-G-E-S-E-F-E-I-L-S-I-N-Y-E-P-L-K-F


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-T-G-V-V-R-R-R-R-H-K-K-V-L-K-L-A-R-G-F-Y-S-G-R-R-K-H-F-R-K-A-K-E-Q-L-E-R-S-L-V-Y-A-Y-R-D-R-R-R-K-K-R-D-F-R-R-L-W-I-V-R-I-N-A-A-C-R-L-N-D-L-S-Y-S-R-F-I-N-G-L-K-K-A-G-I-E-L-D-R-K-I-L-A-D-L-A-M-N-D-A-A-A-F-A-K-I-A-E-A-A-K-K-A-L


### FUNCTION Oxygen-binding protein May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes The oxygen-binding site contains two iron atoms ### SEQUENCE -M-T-Y-N-E-K-I-I-S-M-N-N-D-L-L-D-H-Q-H-K-E-L-F-E-I-S-K-K-L-S-L-M-N-Q-R-H-V-G-T-K-E-L-K-I-V-L-R-E-L-L-I-M-I-N-R-H-F-S-D-E-E-A-F-M-R-E-I-E-Y-P-Y-I-N-H-H-T-R-I-H-R-K-I-I-L-E-I-E-E-I-I-I-S-E-A-K-F-V-N-I-M-T-E-K-L-N-L-V-V-Q-D-F-I-F-K-H-T-A-K-E-D-S-K-I-V-K-Y-Y-E-E-K-F-K-K


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-N-E-I-F-N-K-Q-K-T-Q-S-E-K-S-L-E-A-L-K-K-D-F-T-T-L-R-T-G-K-V-N-I-H-I-L-D-H-I-T-V-D-Y-Y-G-T-Q-T-P-L-N-Q-V-A-T-V-L-A-S-D-A-S-T-I-S-I-T-P-W-E-K-P-L-L-K-T-I-E-S-A-I-A-A-A-N-I-G-V-N-P-N-N-D-G-E-S-V-K-L-F-F-P-P-M-T-R-E-Q-R-E-E-N-V-K-Q-A-K-A-M-G-E-K-A-K-V-S-I-R-N-I-R-K-D-A-N-D-A-V-K-K-L-E-K-D-K-A-I-S-E-D-E-A-K-K-A-Y-D-E-V-Q-K-L-T-D-T-Y-T-T-K-I-D-E-G-V-K-S-K-E-S-E-L-L-K-V


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-S-K-E-K-E-V-L-L-N-E-E-I-R-A-D-E-I-R-C-V-G-D-D-G-K-V-Y-G-I-I-S-S-D-E-A-L-E-I-A-N-R-L-G-L-D-L-V-M-I-A-A-D-A-K-P-P-V-C-K-I-M-D-Y-G-K-F-R-Y-Q-Q-E-K-K-Q-K-E-A-K-K-K-Q-K-V-I-D-I-K-E-I-K-L-S-V-K-I-A-Q-N-D-I-N-Y-K-V-K-H-A-L-E-F-L-E-Q-G-K-H-V-R-F-R-V-F-L-K-G-R-E-M-A-T-P-E-A-G-V-A-L-L-E-K-I-W-T-M-I-E-N-E-A-N-R-D-K-E-P-N-F-E-G-R-Y-V-N-M-L-V-T-P-K-K-A


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-V-R-K-I-I-T-Y-P-N-P-R-L-F-L-N-S-E-I-V-N-K-F-D-T-E-L-H-T-L-L-D-D-M-Y-E-T-M-I-A-S-N-G-V-G-L-A-A-I-Q-V-D-I-P-L-R-V-L-L-V-N-I-F-D-E-N-D-E-Q-K-K-E-D-L-L-E-I-I-N-P-E-I-I-P-L-D-E-E-M-I-T-C-T-E-G-C-L-S-V-P-D-F-F-E-E-V-K-R-Y-N-H-I-L-L-K-Y-Q-D-R-F-G-E-F-K-E-L-E-A-K-G-F-L-A-V-A-I-Q-H-E-N-D-H-L-N-G-H-L-F-I-E-K-I-S-F-A-K-R-Q-K-F-D-K-E-F-K-K-K-K-K-N-H-K-K-E-K


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-D-F-Y-S-L-I-F-L-S-C-A-L-G-M-D-A-F-A-V-S-L-C-K-G-F-S-V-K-K-L-H-L-K-H-Y-L-I-V-G-I-Y-F-G-G-F-Q-A-L-M-P-T-I-G-Y-F-I-G-I-T-F-A-S-F-I-A-S-I-D-H-W-I-A-F-I-L-L-S-L-I-G-L-K-M-I-K-E-S-L-E-N-E-N-C-D-S-N-A-N-Q-F-G-F-K-T-M-L-A-L-A-I-A-T-S-I-D-A-L-A-V-G-V-S-F-A-F-L-N-V-N-L-L-L-A-I-F-L-I-G-I-I-T-F-I-L-C-I-I-A-L-K-I-G-N-K-F-G-I-Y-L-K-N-K-A-E-L-L-G-G-L-V-L-I-I-L-G-V-K-I-L-I-E-H-L-F-F-D


### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-K-E-I-H-P-E-Y-V-E-C-K-V-S-C-A-C-G-N-T-F-T-T-K-S-N-K-A-E-L-R-V-D-I-C-S-N-C-H-P-F-F-T-G-S-E-K-I-V-D-A-A-G-R-V-E-K-F-K-K-K-Y-A-M-Q


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-N-L-E-A-L-C-K-E-A-G-L-S-F-Y-D-D-E-L-V-S-E-N-G-R-K-I-Y-R-I-Y-V-Q-K-E-G-G-V-N-L-D-D-C-A-R-L-S-E-I-L-S-P-I-F-D-V-E-S-P-V-N-G-E-Y-F-L-E-V-S-S-P-G-L-E-R-K-L-S-K-I-E-H-F-A-K-S-I-G-E-L-V-K-I-T-T-N-E-K-E-K-F-E-A-K-I-I-A-V-D-D-E-N-I-T-L-E-N-L-E-N-K-E-K-T-T-I-N-F-N-D-I-K-K-A-R-T-F-V-E-W


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-N-P-S-E-I-K-K-L-R-T-E-S-I-L-K-E-L-I-P-E-A-L-A-N-L-D-D-E-N-L-K-N-L-C-V-V-D-V-E-C-K-K-G-R-Y-D-A-F-V-Y-L-D-K-M-F-F-N-V-H-E-Q-E-K-I-L-S-S-L-K-K-A-S-R-A-L-Q-N-Y-C-M-S-E-Q-G-W-Y-R-C-P-N-F-H-F-K-F-D-D-R-L-E-Y-Q-N-H-M-D-A-L-F-E-K-I-K-K-D-K-N-E-S


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-E-N-N-L-Q-V-N-I-F-C-I-Q-K-S-D-E-F-K-T-C-S-E-K-Y-S-K-L-I-S-K-Y-A-T-L-K-E-I-N-V-F-N-K-K-I-A-L-A-Q-N-L-N-A-I-E-A-K-K-S-Y-E-E-A-F-M-P-Y-K-K-G-Y-C-I-A-L-D-E-K-G-K-D-L-T-S-I-E-F-A-K-L-I-Q-D-K-N-E-L-S-F-F-I-G-G-A-Y-G-L-R-E-E-F-N-Q-S-L-D-F-R-L-S-L-S-K-L-T-L-A-H-Q-F-V-K-T-L-L-L-E-Q-I-Y-R-A-F-C-I-N-N-N-H-P-Y-H-K


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-L-S-D-E-K-C-D-F-L-E-S-I-A-S-F-L-S-P-K-D-V-E-L-V-F-V-D-S-K-E-M-Q-E-I-N-L-E-Q-R-K-Q-D-K-T-T-D-V-L-S-F-P-L-E-N-I-D-E-S-L-P-L-G-S-V-V-I-N-V-D-L-A-K-E-K-A-K-E-L-G-H-S-Y-E-E-E-I-S-L-L-F-I-H-A-M-L-H-L-L-G-F-D-H-E-N-D-N-G-E-M-R-E-K-E-K-E-L-I-E-H-F-N-L-P-K-S-L-I-V-R-T-L-E-D


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-N-D-L-I-N-F-E-I-V-T-P-L-G-V-I-Y-Q-G-E-V-K-S-V-T-L-P-G-S-E-G-E-F-G-V-L-K-G-H-A-A-L-V-S-S-L-K-S-G-V-I-D-I-E-K-A-D-L-N-H-E-L-I-A-I-D-A-G-H-A-K-V-D-E-D-K-I-C-V-L-A-K-G-A-V-W-V-C-G-S-D-E-S-E-I-E-K-N-L-A-Q-A-K-D-L-I-K-S-M-S-S-D-N-A-A-L-A-A-T-F-S-K-L-D-N-A-R-M-H


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-P-R-K-P-S-K-K-V-G-P-Q-K-R-P-S-A-E-K-R-V-I-T-S-K-K-K-Q-L-R-N-Q-S-F-K-S-R-V-K-T-T-L-K-K-F-E-L-A-V-Q-S-G-D-V-A-S-I-S-A-G-L-S-S-V-Y-S-I-A-D-K-A-V-K-R-G-I-F-K-K-G-K-A-D-R-V-K-A-R-A-S-G-R-A-C-P-T-A


### FUNCTION Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin ### SEQUENCE -M-Y-R-L-D-V-T-N-F-R-V-W-V-S-I-G-V-S-E-Q-E-R-Y-H-K-Q-P-I-L-V-S-V-S-L-V-F-R-E-E-P-K-V-C-S-T-D-E-I-S-D-G-I-C-Y-A-A-L-V-S-L-I-E-Q-T-A-A-N-H-P-C-A-L-L-E-R-L-A-K-V-L-L-E-K-L-E-E-S-L-A-Q-F-V-C-K-I-D-L-R-V-S-K-E-R-P-P-I-P-N-L-L-S-P-V-S-F-S-I-S-K-E-V-P


### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-V-Q-I-V-S-Q-D-N-F-A-D-S-I-A-S-G-L-V-L-V-D-F-F-A-E-W-C-G-P-C-K-M-L-T-P-V-L-E-A-L-A-A-E-L-P-Y-V-T-I-L-K-L-D-I-D-A-S-P-R-P-A-E-Q-F-G-V-S-S-I-P-T-L-I-L-F-K-D-G-K-E-V-E-R-S-V-G-L-K-D-K-D-S-L-V-K-L-I-S-K-H-Q


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-K-D-P-Y-D-V-V-K-R-H-Y-V-T-E-K-A-K-M-L-E-G-L-S-L-G-G-G-E-G-K-K-K-G-S-F-C-K-D-P-K-Y-T-F-V-V-A-G-D-A-T-K-P-M-I-A-E-A-I-E-A-I-Y-S-N-K-G-V-K-V-K-K-V-N-T-V-C-V-K-P-Q-P-T-R-I-F-R-G-K-R-K-G-R-T-A-G-F-K-K-A-I-V-T-F-V-D-G-H-S-I-G


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-F-K-A-T-A-R-Y-I-R-V-Q-P-R-K-A-R-L-A-A-G-L-M-R-N-R-S-V-V-E-A-Q-Q-Q-L-S-F-S-Q-M-K-A-G-R-C-L-K-K-V-L-D-S-A-V-A-N-A-E-S-N-E-N-V-K-R-E-N-L-C-V-V-E-V-R-V-D-A-G-P-M-F-K-R-V-K-S-K-S-R-G-G-R-A-P-V-L-K-R-T-S-H-L-T-V-I-V-G-E-R-G-Q


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-F-R-K-Q-Q-K-G-Q-F-A-G-L-S-K-G-A-T-F-V-D-F-G-E-F-G-M-Q-T-L-E-R-G-W-I-T-S-R-Q-I-E-A-C-R-V-A-I-N-R-Y-L-K-R-K-G-K-V-W-I-R-V-F-P-D-K-S-V-T-K-K-P-A-E-T-R-M-G-K-G-K-G-A-P-D-H-W-V-A-V-V-R-P-G-R-I-L-F-E-V-A-N-V-S-K-E-D-A-Q-D-A-L-R-R-A-A-A-K-L-G-I-R-T-R-F-V-K-R-V-E-R-V


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-S-D-V-R-G-R-R-K-T-K-I-G-V-V-V-S-S-K-M-E-K-T-V-V-V-R-V-E-R-V-Y-S-H-P-Q-Y-A-K-V-V-R-D-S-S-K-Y-Y-A-H-N-E-L-D-V-K-E-G-D-T-V-R-I-Q-E-T-R-P-L-S-K-T-K-R-W-R-V-V-D-R-V-N


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-Q-L-K-V-A-D-N-T-G-A-K-K-V-K-C-F-K-V-L-G-G-S-R-R-R-Y-A-T-V-G-D-V-I-V-C-S-V-R-D-V-E-P-D-S-S-V-K-K-G-D-V-V-K-A-V-I-V-R-T-R-N-D-I-R-R-K-D-G-S-T-L-R-F-D-T-N-S-C-V-I-I-D-D-K-G-N-P-K-G-T-R-I-F-G-P-V-A-R-E-I-R-D-R-G-F-I-K-I-S-S-L-A-P-E-V-I


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-R-R-S-V-C-V-G-D-T-V-Y-V-L-A-G-N-D-K-G-K-Q-G-K-V-L-R-C-L-K-D-K-V-V-V-E-G-I-N-V-R-V-K-N-I-K-R-S-Q-E-N-P-K-G-K-R-I-N-I-E-A-P-L-H-I-S-N-V-R-L-S-I-D-N-Q-P-A-R-L-F-V-K-V-T-E-K-G-R-E-L-W-N-K-H-S-D-G-S-S-S-L-Y-R-L-V-R-E-R-K-G


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-S-R-L-K-K-L-Y-T-E-E-I-R-K-T-L-Q-D-K-F-Q-Y-E-N-V-M-Q-I-P-V-L-K-K-I-V-I-S-M-G-L-A-E-A-A-K-D-K-N-L-F-Q-S-H-L-E-E-L-A-V-I-S-G-Q-K-P-L-V-T-R-A-K-N-S-I-A-G-F-K-L-R-E-G-Q-G-I-G-A-K-V-T-L-R-G-I-R-M-Y-D-F-M-D-R-F-C-N-I-V-S-P-R-I-R-D-F-R-G-F-S-C-K-G-D-G-R-G-C-Y-S-L-G-L-D-D-Q-Q-I-F-P-E-V-D-L-D-R-V-K-R-S-Q-G-M-N-I-T-W-V-T-T-A-Q-T-D-A-E-C-L-T-L-L-E-C-M-G-L-R-F-K-K-A-Q


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-I-T-S-D-S-I-A-N-L-L-T-R-I-R-N-A-L-M-A-E-H-L-Y-I-D-I-E-H-S-K-M-L-E-A-I-V-R-I-L-K-Q-H-G-F-V-A-H-F-L-V-K-E-E-N-R-K-R-L-M-R-V-F-L-R-Y-G-E-D-R-R-P-V-I-H-A-L-K-R-V-S-K-P-S-R-R-V-Y-V-S-A-A-K-I-P-Y-V-F-G-N-M-G-I-A-V-L-S-T-P-Q-G-V-L-E-G-S-E-A-R-A-K-N-V-G-G-E-L-L-C-L-V-W


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-K-A-R-D-P-I-V-L-P-Q-G-V-E-V-S-I-Q-N-D-E-I-S-V-K-G-P-K-G-S-L-T-Q-V-L-A-K-E-V-E-I-A-V-K-G-N-E-V-F-V-S-P-A-A-H-I-I-D-R-P-G-R-M-Q-G-L-Y-W-A-L-I-A-N-M-V-K-G-V-H-L-G-F-E-K-R-L-E-M-I-G-V-G-F-R-A-S-V-Q-G-S-F-L-D-L-S-I-G-V-S-H-P-T-K-M-P-I-P-T-G-L-E-V-S-V-E-K-N-T-L-I-S-I-K-G-I-N-K-Q-L-V-G-E-F-A-A-C-V-R-A-K-R-P-P-E-P-Y-K-G-K-G-I-R-Y-E-N-E-Y-V-R-R-K-A-G-K-A-A-K-T-G-K-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-E-S-S-L-Y-K-K-T-S-G-K-A-R-R-A-L-R-V-R-K-A-L-K-G-S-S-L-K-P-R-L-S-V-V-K-T-N-K-H-I-Y-V-Q-L-I-D-D-V-E-G-K-T-L-A-S-I-S-T-L-A-K-I-S-K-T-S-G-L-T-K-K-N-Q-D-N-A-K-A-L-G-V-K-I-A-E-L-G-K-S-L-Q-V-D-R-I-V-F-D-R-G-A-H-K-Y-H-G-V-V-A-M-V-A-D-G-A-R-E-G-G-L-Q-F


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-I-K-L-E-Y-L-Q-D-P-S-P-R-K-R-R-T-K-L-L-G-R-G-P-S-S-G-H-G-K-T-S-G-R-G-H-K-G-D-G-S-R-S-G-Y-K-R-R-F-G-Y-E-G-G-G-V-P-L-Y-R-R-V-P-T-R-G-F-S-H-K-R-F-D-K-C-V-E-E-I-T-T-Q-R-L-N-G-I-F-E-N-G-E-E-V-S-L-E-T-L-K-Q-R-K-V-I-H-R-E-T-S-R-V-K-V-I-L-K-G-A-L-D-K-K-L-V-W-K-D-A-A-I-V-L-S-E-G-V-K-S-L-I-E-T-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-P-R-I-I-G-I-D-I-P-A-K-K-K-L-K-I-S-L-T-Y-I-Y-G-I-G-P-A-L-S-E-E-I-I-A-R-L-Q-L-N-P-E-A-R-A-A-E-L-T-E-E-E-V-G-R-L-N-A-L-L-Q-S-D-Y-V-V-E-G-D-L-R-R-R-V-Q-S-D-I-K-R-L-I-T-I-H-A-Y-R-G-Q-R-H-R-L-S-L-P-V-R-G-Q-R-T-K-T-N-S-R-T-R-K-G-K-R-K-T-V-A-G-K-K-K


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-V-K-N-Q-T-Q-K-K-G-V-K-R-K-Q-V-K-N-I-P-S-G-V-V-H-V-K-A-T-F-N-N-T-I-V-T-I-T-D-P-A-G-N-V-I-S-W-A-S-A-G-K-V-G-Y-S-G-S-R-K-S-S-A-F-A-A-T-V-A-A-Q-D-A-A-K-T-A-M-S-S-G-L-K-E-V-E-V-S-L-K-G-T-G-A-G-R-E-S-A-V-R-A-L-I-S-S-G-L-I-V-S-V-I-R-D-E-T-P-V-P-H-N-G-C-R-P-R-K-R-R-R-V


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-E-Y-I-K-G-K-L-T-H-T-D-E-A-Y-V-V-I-E-S-F-G-I-G-Y-S-I-M-L-S-E-R-F-L-V-D-L-R-E-L-M-H-Q-E-V-L-I-Y-V-H-S-V-I-R-E-T-E-H-S-L-Y-G-F-S-S-R-A-E-R-E-C-F-R-L-L-I-S-F-S-G-I-G-P-K-T-G-L-A-I-L-N-M-F-P-L-Q-E-L-C-S-V-A-R-L-E-N-V-K-A-I-A-S-V-P-G-I-G-K-K-T-A-E-K-L-M-V-D-L-K-Q-K-L-P-A-L-M-P-L-Y-L-E-E-P-V-V-A-S-S-S-T-T-T-S-F-K-E-G-I-G-A-L-M-N-L-G-F-S-R-L-A-A-D-R-M-M-T-E-A-V-K-E-L-S-E-D-A-S-V-A-E-L-L-P-V-A-L-R-K-G


### FUNCTION In elementary bodies ### SEQUENCE -M-K-K-T-A-L-L-A-A-L-C-S-V-V-S-L-S-S-C-C-R-I-V-D-C-C-F-E-D-P-C-A-P-I-K-C-S-P-C-E-S-K-K-R-E-V-N-G-G-C-N-S-C-N-G-Y-V-P-S-C-K-P-C-G-G-E-L-D-H-E-T-K-Q-G-P-Q-A-R-G-I-Q-A-D-G-R-C-R-Q


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-A-A-E-K-K-V-I-P-G-D-P-V-Y-G-S-V-V-L-E-R-F-I-N-K-V-M-L-H-G-K-K-S-I-A-R-K-I-V-Y-G-A-L-E-R-F-A-K-R-L-G-L-E-N-P-L-E-G-F-E-E-A-L-E-N-A-K-P-I-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-A-P-D-R-R-S-C-L-A-M-Q-W-I-I-K-H-A-R-S-K-P-G-K-C-M-E-I-G-L-A-N-E-L-I-D-C-F-N-K-Q-G-A-T-I-K-K-R-E-D-T-H-R-M-A-E-A-N-K-A-F-A-H-Y-K-W


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-L-I-L-D-R-S-S-P-Q-I-F-I-S-N-E-Q-Q-D-V-D-I-D-L-Q-S-V-Q-R-L-V-I-L-F-L-E-L-Q-K-V-S-T-D-Q-V-Y-I-Y-F-L-S-D-A-A-L-A-Q-L-H-D-E-Q-F-S-D-P-S-L-T-D-T-I-T-L-P-I-D-R-P-G-I-Q-S-F-P-H-V-L-G-E-A-F-V-S-P-R-A-A-M-R-F-L-G-Q-Y-T-E-A-Q-L-Y-H-E-I-S-R-Y-V-V-H-S-L-L-H-M-L-G-Y-D-D-Q-T-D-E-D-K-R-I-M-R-E-Q-E-D-S-S-L-T-F-L-A-Q-N-Q-A-L-L-H-P-T-V


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-E-P-Y-A-V-V-Q-T-G-N-K-Q-Y-Q-V-R-K-G-D-V-I-D-V-E-L-L-D-G-I-S-E-E-N-K-E-V-L-F-Q-E-V-L-F-V-F-D-G-E-K-A-S-V-G-S-P-T-V-G-N-A-V-V-K-G-E-L-I-S-F-V-R-G-E-K-V-V-A-Y-K-Y-K-K-R-K-N-Y-H-K-K-I-G-H-R-Q-N-Y-L-R-V-K-I-C-D-L-V-M


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-L-C-P-F-C-N-H-G-E-L-K-V-I-D-S-R-N-S-P-E-A-N-A-I-K-R-R-R-E-C-L-R-C-S-Q-R-F-T-T-F-E-T-V-E-L-T-I-Q-V-L-K-R-D-G-R-Y-E-N-F-Q-E-A-K-L-I-N-G-L-K-A-A-S-S-H-T-R-I-G-Q-E-Q-V-Q-A-I-A-S-N-I-K-Q-D-L-L-G-K-Q-N-R-E-I-S-T-K-E-I-G-E-L-V-M-K-Y-L-K-K-A-D-M-I-A-Y-I-R-F-A-C-V-Y-R-R-F-R-D-V-G-E-L-M-E-V-L-L-S-A-T-P-D-G-E-K


### FUNCTION Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-uracil ### SEQUENCE -M-F-S-G-I-I-Q-E-V-A-R-V-D-L-I-H-H-Y-G-D-S-M-E-I-G-I-F-A-R-N-L-V-D-G-V-P-G-S-S-I-A-V-D-G-I-C-L-T-L-V-K-R-E-F-E-L-L-F-F-D-V-T-E-E-T-M-A-C-T-T-I-K-N-Y-T-V-G-S-M-V-N-L-E-R-S-V-R-L-G-D-E-I-G-G-H-F-V-S-G-H-V-C-G-V-G-T-I-I-A-V-E-K-S-Y-M-F-F-K-A-P-T-N-L-V-P-Y-V-L-E-K-G-F-I-A-I-D-G-I-S-L-T-I-A-Q-V-R-G-D-I-F-S-V-S-V-I-P-E-T-R-A-R-T-S-L-G-Y-K-Q-V-G-S-H-V-N-M-E-P-D-M-M-T-K-M-Q-V-D-T-V-M-R-F-Q-A-E-K-I-G-K


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-R-D-L-E-Y-Y-D-S-P-I-L-R-K-V-A-A-P-I-D-E-I-T-D-E-L-R-Q-L-V-L-D-M-S-E-T-M-T-F-Y-K-G-V-G-L-A-A-P-Q-V-G-H-S-V-A-L-F-I-M-G-V-E-K-E-L-D-D-G-E-L-I-F-C-D-F-P-K-V-F-I-N-P-V-I-T-Q-K-S-E-Q-L-V-Y-G-N-E-G-C-L-S-I-P-G-L-R-G-E-V-A-R-P-D-K-I-T-V-T-A-K-N-L-D-G-Q-P-F-S-M-T-L-E-G-F-L-A-R-I-V-M-H-E-T-D-H-L-H-G-V-L-Y-I-D-R-M-S-D-K-D-K-T-K-Q-F-K-N-N-L-E-K-I-R-R-K-Y-S-I-L-R-G-L


### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-G-T-Q-L-V-L-G-S-S-S-K-I-R-K-A-V-L-E-A-F-R-I-P-F-I-C-V-S-S-D-F-D-E-R-S-I-T-Y-S-G-D-P-F-E-Y-T-R-E-L-A-W-N-K-A-N-A-V-R-S-Q-G-F-S-D-S-L-I-I-T-A-D-T-V-V-V-Y-E-G-E-V-F-N-K-P-E-S-E-E-H-A-V-E-M-L-R-T-L-S-G-T-S-H-S-V-I-T-S-L-V-L-M-Q-N-E-K-V-A-S-A-S-E-T-T-Q-V-S-F-I-D-I-P-P-Q-H-L-K-T-Y-V-Q-A-F-S-S-L-K-R-C-G-G-Y-C-V-Q-D-G-G-G-L-I-I-K-Q-I-E-G-C-V-Y-N-I-Q-G-L-P-I-K-T-L-N-Q-L-L-M-E-F-N-I-S-L-W-D-Y-L-A


### FUNCTION General  is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-S-G-G-D-D-L-V-L-H-N-P-V-E-D-G-E-L-S-A-I-F-M-I-R-N-P-S-G-I-H-V-R-P-A-G-T-I-V-K-L-F-D-G-E-D-C-E-A-T-F-T-Y-L-G-K-T-V-N-A-R-S-V-M-S-I-L-M-L-G-A-S-Y-N-G-E-I-T-V-R-I-K-G-P-S-A-S-R-V-M-Q-K-L-A-E-V-F-N-S-G-F-G-E-L


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-G-S-G-Y-A-K-K-K-K-E-A-K-L-M-E-R-Q-F-M-E-M-E-A-S-L-E-Q-K-R-F-S-G-E-A-G-N-G-L-V-S-V-T-I-N-G-K-C-N-L-V-D-V-K-I-K-P-D-C-L-D-P-E-D-P-E-V-V-A-D-L-F-R-A-A-F-K-A-A-K-A-A-L-D-S-E-M-S-A-M-H-M-G-M-P-F


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-T-K-K-A-K-N-V-E-K-V-P-F-E-D-A-M-K-R-L-E-E-I-I-D-L-M-N-Q-P-T-T-A-L-E-A-S-L-A-L-Y-E-E-A-D-Q-L-M-R-I-C-E-S-R-I-Q-E-V-E-A-R-I-K-Q-L-S-D-Q-R-S-E-S


### FUNCTION Participates in transcription elongation, termination and antitermination ### SEQUENCE -M-F-K-W-Y-V-V-Q-V-F-T-A-Q-E-K-K-V-K-K-S-L-E-D-F-K-E-A-S-G-M-S-D-F-I-Q-Q-I-I-L-P-S-E-N-V-M-E-V-K-K-G-E-H-K-I-V-E-K-Y-I-W-P-G-Y-L-L-V-K-M-H-L-T-D-E-S-W-S-Y-V-K-K-T-Q-G-V-V-E-F-L-G-G-G-A-P-V-A-L-S-E-E-E-V-K-N-I-L-A-D-L-E-E-K-K-S-G-V-V-Q-K-H-K-F-E-V-G-S-Q-V-K-I-N-D-G-V-F-V-N-F-V-G-V-V-S-E-V-F-H-D-K-G-R-L-S-V-M-V-S-I-F-G-R-E-T-R-V-D-D-L-E-F-W-Q-V-E-E-V-A-P-G-Q-E-S-E


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-S-N-K-K-I-I-K-I-I-K-L-Q-I-P-G-G-K-A-N-P-A-P-P-I-G-P-A-L-G-A-A-G-V-N-I-M-G-F-C-K-E-F-N-A-A-T-Q-D-R-P-G-D-L-L-P-V-V-I-T-V-Y-S-D-K-T-F-S-F-V-M-K-Q-P-P-V-S-S-L-I-K-K-A-L-G-L-E-S-G-S-K-I-P-N-R-N-K-V-G-K-L-A-R-A-Q-I-T-A-I-A-E-Q-K-M-K-D-M-D-V-V-L-L-E-S-A-E-R-M-V-E-G-T-A-R-S-M-G-V-D-V-E


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-K-E-E-K-K-L-L-L-R-E-V-E-E-K-I-T-A-S-Q-G-F-I-L-L-R-Y-L-G-F-T-A-A-H-S-R-S-F-R-N-N-L-S-G-V-S-A-E-F-E-V-L-K-K-K-I-F-F-K-A-L-E-S-S-G-V-E-M-D-P-E-D-S-E-G-H-L-G-V-V-F-A-Y-G-D-P-V-S-A-A-K-Q-V-L-D-F-N-K-Q-H-N-D-S-L-V-F-L-A-G-R-I-D-N-A-S-L-S-G-K-E-V-E-A-V-A-K-L-P-S-M-K-E-L-R-Q-Q-V-V-G-L-I-A-A-P-M-S-Q-V-V-G-I-M-N-S-V-L-S-G-V-I-S-C-V-D-Q-K-A-E-K-T-Q-E


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-L-K-Y-P-D-Y-I-S-K-L-I-S-F-L-K-K-L-P-G-I-G-F-K-S-A-E-K-I-A-F-E-L-L-E-W-D-P-S-Q-V-E-A-M-G-L-A-M-Q-E-F-S-A-S-H-A-T-C-P-D-C-F-C-L-K-T-S-K-T-S-S-C-D-F-C-S-E-S-R-D-S-S-F-L-C-I-V-A-T-P-K-D-V-F-S-F-E-K-S-K-I-F-K-G-R-Y-F-V-L-G-N-L-L-S-P-I-T-G-K-H-L-S-L-E-K-L-N-I-L-K-Q-R-I-E-D-F-A-P-K-E-M-I-I-A-L-D-A-T-L-E-G-D-A-T-A-L-F-L-K-Q-E-F-S-H-L-P-I-K-I-S-R-L-A-L-G-M-P-V-G-L-S-F-D-F-I-D-S-N-T-L-A-R-A-F-S-G-R-N-C-F


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-L-E-D-D-V-K-A-I-I-V-D-Q-L-G-V-S-P-E-D-V-K-E-S-S-S-F-I-E-D-L-N-A-D-S-L-D-L-T-E-L-I-M-T-L-E-E-K-F-A-F-E-I-S-E-N-D-A-E-Q-L-R-T-V-G-D-V-I-K-Y-I-Q-E-R-Q-N


### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor  to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-K-R-Y-I-V-G-I-S-G-A-S-G-A-I-L-A-V-T-L-V-S-E-L-A-R-L-G-H-H-V-D-V-I-I-S-P-A-A-Q-K-T-L-Y-Y-E-L-E-T-K-S-F-L-A-T-I-P-S-N-L-H-K-N-I-L-I-H-R-I-T-S-I-E-S-S-L-S-S-G-S-T-L-V-D-A-T-I-I-V-P-C-S-V-A-T-I-A-A-I-S-C-G-L-S-D-N-L-L-R-R-V-A-D-V-A-L-K-E-K-R-P-L-I-L-V-P-R-E-T-P-L-S-A-I-H-L-E-N-L-L-K-L-A-Q-N-G-A-V-I-L-P-P-M-P-T-W-Y-F-R-P-E-T-A-N-D-I-A-N-D-I-V-G-K-I-L-A-I-L-Q-L-D-S-P-L-I-K-R-W-E-N-P-H


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-N-S-M-K-Q-K-E-A-F-L-G-V-D-Y-G-K-K-R-I-G-L-A-F-A-S-A-P-L-L-I-T-L-P-I-G-S-I-N-T-C-S-S-L-A-L-T-A-Q-A-L-I-T-I-I-K-E-R-A-V-T-T-V-V-F-G-N-P-L-P-M-Q-K-S-Y-A-S-S-V-Q-S-E-I-Q-E-L-A-A-L-V-R-D-M-T-S-L-E-V-I-L-W-D-E-R-L-S-S-A-Q-A-E-R-M-L-K-N-D-C-G-L-S-R-K-Q-R-K-N-S-S-D-S-L-A-A-T-L-I-L-S-S-F-L-D-S-R-K-L-Y


### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-I-K-L-L-R-S-Y-C-L-Y-F-A-W-L-V-S-C-I-G-T-L-M-S-V-Y-Y-S-Y-L-L-N-V-E-P-C-V-L-C-Y-Y-Q-R-I-C-L-F-P-L-V-V-I-L-G-I-S-A-Y-L-D-D-L-S-V-K-I-Y-A-L-P-L-A-L-I-G-F-C-I-A-I-Y-Q-V-C-L-Q-E-I-P-G-M-T-L-D-I-C-G-K-V-S-C-S-T-K-L-F-L-L-G-F-I-T-M-P-M-A-S-A-L-A-F-F-A-I-A-N-L-L-I-F-A-T-K-S-E


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-E-K-R-K-D-T-K-T-T-L-A-K-A-S-D-D-Q-N-K-A-W-Y-V-I-N-A-E-G-K-T-L-G-R-L-S-S-E-V-A-K-I-L-R-G-K-H-K-V-T-F-T-P-H-V-A-M-G-D-G-V-I-V-I-N-A-E-K-V-R-L-T-G-A-K-R-A-Q-K-V-Y-H-Y-Y-T-G-F-I-S-G-M-R-E-V-P-F-E-N-M-I-A-R-K-P-A-Y-V-I-E-H-A-V-K-G-M-L-P-K-T-K-L-G-R-R-Q-M-K-S-L-R-V-V-K-G-S-S-Y-A-Q-Y-E-A-I-K-P-I-V-L-D-A


### FUNCTION This protein is a component of the acetyl coenzyme A carboxylase complex ### SEQUENCE -M-D-L-K-Q-I-E-K-L-M-I-A-M-G-R-N-K-M-K-R-I-A-I-K-R-D-G-F-E-L-E-L-E-R-D-T-G-P-N-I-Q-E-P-V-F-Y-D-N-R-L-F-A-G-F-T-Q-E-R-P-I-P-S-D-Q-N-L-G-N-P-I-V-K-E-V-G-E-K-K-E-D-K-P-V-E-G-D-F-I-V-S-P-L-V-G-T-F-Y-G-A-P-S-P-E-S-P-A-F-V-K-P-G-D-I-V-S-E-D-T-V-V-C-I-V-E-A-M-K-V-M-N-E-V-K-A-G-M-A-G-R-V-E-E-V-L-I-T-N-G-D-P-V-Q-F-G-S-K-L-F-R-I-V-K-A


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-L-S-S-Q-L-S-V-G-M-F-I-S-T-K-D-G-L-Y-K-V-V-S-V-S-K-V-S-G-S-K-G-D-T-F-I-K-V-A-L-Q-A-A-G-S-D-V-V-V-E-R-N-F-K-A-G-Q-E-V-K-E-A-Q-F-E-P-R-N-L-E-Y-L-Y-L-E-E-D-N-Y-L-F-L-D-L-G-N-Y-E-K-I-Y-I-P-K-E-I-M-K-E-N-A-M-F-L-K-A-G-V-T-I-S-A-L-V-H-E-G-I-V-F-S-M-E-L-P-H-F-L-E-L-M-V-S-K-T-D-F-P-G-D-S-L-S-L-S-G-G-A-K-K-A-L-L-E-T-G-V-E-V-L-V-P-P-F-V-E-I-G-D-V-I-K-V-D-T-R-T-C-E-Y-I-Q-R-V


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-F-G-I-G-T-D-I-I-E-I-D-R-I-R-R-A-Y-H-T-Y-G-D-R-F-L-N-K-I-F-T-K-G-E-Q-A-Y-C-F-S-K-S-D-P-Y-A-S-L-A-V-R-F-A-A-K-E-A-V-S-K-A-L-G-T-G-I-G-K-S-L-K-W-K-E-I-E-I-S-R-G-T-Q-H-P-Q-V-S-V-P-E-S-L-L-A-L-L-E-V-K-R-I-L-L-S-M-S-H-C-R-E-Y-A-T-A-V-A-I-A-E-V-T-N-S-S-K


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-T-E-N-R-R-M-K-K-V-N-A-M-L-R-E-S-I-A-K-V-I-L-K-D-V-K-H-P-K-I-S-N-R-W-I-T-I-T-R-V-S-L-S-R-D-L-Q-S-A-R-V-Y-V-S-I-M-P-H-E-N-S-Q-E-E-T-L-A-A-L-K-A-S-A-G-F-I-A-C-Q-A-S-K-D-V-V-L-K-Y-F-P-D-L-N-F-Y-M-E-D-I-F-S-P-Q-D-H-I-E-S-L-L-L-K-I-A-E-Q-D-K-K-L-T-H-N-N-N-N-S-S-E-L-H-D


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-V-K-E-I-V-S-N-R-K-A-F-H-N-Y-E-V-L-E-T-F-D-A-G-I-V-L-T-G-T-E-I-K-S-L-R-D-H-G-G-N-L-G-D-A-Y-V-T-I-S-K-G-E-A-W-L-L-Q-S-S-I-A-P-Y-R-F-G-N-I-N-N-H-E-E-R-R-K-R-K-L-L-L-H-K-Y-E-L-Q-K-L-D-S-R-V-S-Q-K-G-L-T-I-I-P-L-S-F-F-F-S-K-G-F-V-K-V-R-I-G-C-C-R-G-K-K-S-H-D-K-R-Q-A-L-I-E-R-E-K-N-R-E-L-A-A-A-M-K-R-S-Y-R


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-G-N-L-I-K-E-L-Q-D-E-Q-C-R-T-D-L-V-D-F-C-V-G-D-T-I-R-V-A-T-N-I-S-E-G-G-K-E-R-V-Q-V-F-Q-G-T-V-M-A-R-K-G-G-G-A-G-E-T-V-S-L-H-R-V-A-Y-G-E-G-M-E-K-S-F-L-L-N-S-P-K-V-V-S-I-E-V-V-K-R-G-K-V-S-R-A-R-L-F-Y-L-R-G-K-T-G-K-A-A-K-V-K-E-L-I-G-P-R-A-A-K-K


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-T-Q-S-Y-V-N-K-E-E-I-I-S-L-A-K-N-A-A-L-E-L-E-E-A-H-V-E-E-F-V-T-S-M-N-N-V-I-A-L-M-Q-E-V-V-A-I-D-I-S-D-I-I-L-E-A-T-V-H-H-F-V-G-P-E-D-L-R-E-D-M-V-T-S-D-F-T-R-E-E-F-L-A-N-V-P-V-S-L-G-G-L-V-K-V-P-T-V-I-K


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-A-T-G-S-V-A-S-R-A-R-R-K-R-I-L-K-Q-A-K-G-F-W-G-D-R-K-G-H-F-R-Q-S-R-S-S-V-M-R-A-M-A-F-N-Y-M-H-R-K-D-R-K-G-D-F-R-S-L-W-I-S-R-L-N-V-A-S-R-I-H-G-L-S-Y-S-R-L-I-N-G-L-K-Q-A-G-I-N-L-N-R-K-M-L-S-E-M-A-I-H-D-P-Q-G-F-A-L-V-A-A-Q-A-K-L-A-L-E-A-S-I-Q-G


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-A-L-N-L-K-I-N-R-Q-I-R-A-P-R-V-R-V-I-G-S-S-G-E-Q-L-G-I-L-S-I-K-E-A-L-D-L-A-R-E-A-D-L-D-L-V-E-V-A-S-N-S-E-P-P-V-C-K-I-M-D-Y-G-K-Y-R-Y-D-V-T-K-K-E-K-D-S-K-K-A-Q-H-Q-V-R-V-K-E-V-K-L-K-P-N-I-D-D-N-D-F-L-T-K-V-K-Q-A-R-A-F-I-E-K-G-N-K-V-K-V-S-C-M-F-R-G-R-E-L-A-Y-P-E-H-G-H-K-V-V-Q-R-M-C-Q-G-L-E-D-V-G-F-V-E-S-E-P-K-L-N-G-R-S-L-I-C-V-I-A-P-G-T-L-K-T-K-K-K-Q-E-K-V-H-A-Q-D-E-K-Q


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-I-M-S-V-M-A-S-D-S-A-R-A-V-V-C-T-S-R-P-F-P-K-Q-K-L-R-E-L-V-L-Q-A-L-Y-A-L-E-M-A-P-K-G-E-D-S-L-V-S-L-L-M-T-E-A-S-V-S-K-K-N-V-L-Y-A-L-M-F-C-K-A-I-R-A-N-Q-S-E-L-D-A-L-L-N-A-T-I-R-T-T-T-L-A-N-L-T-I-I-E-R-N-I-L-R-M-M-L-F-E-H-Q-Q-N-Q-E-S-S-P-I-P-T-A-V-L-I-A-E-T-T-R-L-I-K-K-F-S-Y-V-E-G-S-S-L-I-L-A-V-L-G-S-I-F-D-Q-V-A-Q-E-P-A-S-M-C-G


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-K-K-K-T-G-Q-L-Y-E-G-A-Y-V-F-S-V-T-L-S-E-D-A-R-R-K-A-L-E-K-V-T-S-G-I-T-N-Y-G-G-E-V-L-K-I-H-D-Q-G-R-K-K-L-A-Y-T-I-R-G-A-R-E-G-Y-Y-Y-F-I-Y-F-T-V-A-P-E-A-I-S-E-L-W-R-E-Y-H-L-N-E-D-L-L-R-F-M-T-L-K-A-S-A-V-K-E-V-L-E-F-A-T-L-P-E


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-E-L-V-V-Q-S-R-E-T-D-K-K-S-V-I-K-K-I-R-Q-Q-G-G-I-P-A-V-L-Y-S-G-G-K-S-L-A-N-V-V-I-D-A-R-V-F-N-K-F-L-S-T-L-E-S-G-A-L-A-S-T-V-F-T-L-S-Y-E-G-R-E-I-K-A-L-V-K-D-I-Q-Y-H-V-T-T-Y-D-V-I-H-L-D-F-E-E-L-V-E-D-R-E-V-R-L-N-I-P-I-R-C-I-N-T-V-D-C-V-G-V-K-L-G-G-S-L-R-Q-V-I-R-Y-M-R-V-V-C-K-P-K-D-I-V-P-F-L-E-L-D-V-Q-S-L-G-L-S-Q-T-L-K-L-S-D-I-R-I-P-E-G-I-K-P-V-T-P-L-K-E-V-A-V-T-V-A-R-R


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-A-V-A-R-E-V-K-R-R-K-L-V-E-A-N-F-Q-K-R-A-E-L-R-K-L-A-K-S-L-S-V-S-E-E-E-R-E-R-A-R-E-A-L-N-K-M-K-R-D-T-S-P-S-R-L-H-N-R-C-L-L-T-G-R-P-R-G-Y-L-R-K-F-A-I-S-R-I-C-F-R-Q-M-A-S-M-G-D-I-P-G-V-I-K-A-S-W


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-H-R-L-T-L-P-K-S-A-R-L-L-K-R-K-Q-F-V-Y-V-Q-R-C-G-Q-Y-C-R-T-D-Q-A-T-L-R-I-V-P-S-R-H-S-N-I-R-K-V-G-V-T-V-S-K-K-F-G-K-A-H-Q-R-N-R-F-K-R-I-V-R-E-A-F-R-H-V-R-P-N-L-P-A-C-Q-V-V-V-S-P-K-G-G-T-L-P-N-F-G-K-L-S-A-D-L-L-K-H-I-P-E-A-L-P-L-V-T-S-S-K


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-R-V-S-T-S-E-F-R-V-G-L-R-V-E-I-D-G-Q-P-Y-V-I-L-Q-N-D-F-V-K-P-G-K-G-Q-A-F-N-R-I-K-V-K-N-F-L-T-G-R-V-I-E-K-T-F-K-S-G-E-S-I-E-T-A-D-V-R-E-Q-Q-M-R-L-L-Y-T-D-Q-E-G-A-T-F-M-D-D-E-T-F-E-Q-E-L-I-F-W-D-K-L-E-N-I-R-Q-W-L-L-E-D-T-V-Y-T-L-V-R-Y-N-G-D-V-I-S-V-E-P-P-I-F-M-E-L-S-I-A-E-T-A-P-G-V-R-G-D-T-A-S-G-R-V-L-K-P-A-T-T-N-T-G-A-K-I-M-V-P-I-F-I-E-E-G-E-V-V-K-V-D-T-R-T-G-S-Y-E-S-R-V-S-K


### FUNCTION Might have a role analogous to that of eukaryotic histone proteins ### SEQUENCE -M-A-L-K-D-T-A-K-K-M-T-D-L-L-E-S-I-Q-Q-N-L-L-K-A-E-K-G-N-K-A-A-A-Q-R-V-R-T-E-S-I-K-L-E-K-I-A-K-V-Y-R-K-E-S-I-K-A-E-K-M-G-L-M-K-R-S-K-V-A-A-K-K-A-K-A-A-A-K-K-P-A-K-A-T-K-V-V-T-K-K-A-C-T-K-K-T-C-A-T-K-A-K-A-K-P-V-K-K-A-A-T-K-T-K-A-K-V-T-K-K-V-R-S-T-K-K


### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon  protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-F-S-R-V-L-F-S-I-L-F-F-L-G-C-C-P-S-L-F-A-D-V-D-S-P-Q-R-A-T-F-G-Q-P-A-V-M-L-G-I-A-I-V-F-F-Y-F-I-L-W-R-P-E-Q-K-R-R-Q-A-M-E-K-R-K-S-E-L-A-V-G-D-K-V-T-A-M-G-I-V-G-T-I-A-E-I-R-E-H-T-V-V-L-N-I-A-S-G-K-I-E-I-L-K-A-A-I-S-E-I-F-K-A-E-K


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-L-L-K-G-L-P-V-A-K-D-V-R-V-A-I-V-G-A-C-F-N-A-P-I-A-D-R-L-V-S-G-A-R-E-T-F-F-E-S-G-G-S-P-D-S-L-T-V-V-R-V-P-G-A-F-E-I-P-C-A-I-K-K-M-L-S-K-G-N-L-F-Q-A-I-V-A-C-G-V-L-I-Q-G-E-T-S-H-Y-E-H-I-A-D-N-V-A-A-G-I-A-R-L-S-V-E-F-C-L-P-I-T-F-S-V-I-T-A-P-N-V-E-A-A-W-E-R-A-G-I-K-G-P-N-L-G-A-S-G-M-R-T-A-L-E-M-A-S-L-F-S-L-I-E-K-E


### FUNCTION A probable RNA-binding protein ### SEQUENCE -M-K-E-F-L-A-Y-I-V-K-N-L-V-D-R-P-E-E-V-H-L-K-E-V-Q-G-T-N-T-I-I-Y-E-L-T-V-A-K-G-D-I-G-K-I-I-G-K-E-G-R-T-I-K-A-I-R-T-L-L-V-S-V-A-S-R-D-N-V-K-V-S-L-E-I-M-E-E-R


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-Q-K-F-I-I-H-K-G-I-A-C-P-L-E-Y-A-N-I-D-T-D-Q-I-I-P-K-Q-F-L-L-A-V-S-K-Q-G-F-G-K-H-L-F-H-D-L-R-Y-L-D-D-K-E-S-V-L-N-M-D-F-N-L-N-K-K-E-Y-Q-N-S-S-I-L-V-S-F-E-N-F-G-S-G-S-S-R-E-H-A-P-W-A-L-V-D-Y-G-I-R-A-I-I-A-P-S-F-A-D-I-F-K-N-N-A-L-G-N-G-L-L-T-I-E-L-A-K-D-E-V-L-E-I-V-D-E-L-K-K-S-Q-D-K-N-I-E-I-S-L-L-E-K-R-V-F-F-K-D-K-I-F-S-F-D-L-D-D-F-H-R-I-C-L-L-E-G-L-D-N-I-A-L-T-L-K-H-E-A-Q-I-K-A-Y-E-K-N-S-K-S-F-L-V


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-E-R-I-R-L-K-L-K-A-Y-D-H-R-V-L-D-R-T-V-A-A-I-V-E-A-V-K-R-T-G-A-D-I-R-G-P-I-P-M-P-T-K-I-K-R-Y-T-V-L-K-S-P-H-I-N-K-D-S-R-E-Q-F-E-I-R-I-H-A-R-M-L-D-I-V-A-A-T-P-D-T-V-D-S-L-T-K-L-D-L-A-P-E-V-S-V-E-V-R-A-M-G-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-E-Y-I-V-E-K-I-G-M-S-R-T-I-T-N-P-S-I-A-V-T-L-L-R-V-V-N-A-K-V-C-E-V-E-G-G-K-A-L-V-A-Y-P-K-G-K-A-S-N-K-C-V-A-G-Q-Q-K-K-Y-N-L-S-A-E-Y-N-R-F-A-T-L-E-V-A-N-T-E-A-G-D-L-D-E-T-P-L-N-E-A-K-I-L-K-V-S-F-N-T-K-G-R-G-Y-S-G-V-M-K-R-H-N-F-A-G-G-P-A-S-H-G-S-R-F-H-R-R-H-G-S-I-G-N-R-E-W-P-G-R-V-Q-P-G-M-K-M-A-G-H-Y-G-N-T-K-V-T-I-K-N-E-V-V-S-Y-D-A-E-N-K-I-L-V-V-K-G-A-V-P-G-Y-N-G-A-M-G-K-I-R-I-A-K


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-V-D-D-H-V-M-K-K-V-I-A-A-K-K-A-N-D-N-K-P-I-K-T-W-S-R-R-S-T-I-T-P-D-M-I-G-L-T-F-N-V-H-N-G-K-S-F-I-P-V-Y-I-T-E-N-H-I-G-Y-K-L-G-E-F-A-P-T-R-T-F-K-G-H-K-G-S-V-Q-K-K-I-G-K


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-K-A-L-I-K-F-I-R-L-S-P-T-K-A-R-L-I-A-R-E-V-Q-G-M-N-A-E-L-A-M-A-S-L-K-F-M-P-N-K-G-A-K-Y-I-A-N-A-I-S-S-A-V-A-N-G-G-F-E-A-N-E-V-I-V-K-S-C-R-V-D-A-A-A-V-L-K-R-F-R-P-R-A-R-G-S-A-S-R-I-R-K-P-T-S-H-I-L-V-E-V-A-K-A-E-V-K-S-E-E-K-K-T-V-A-K-K-T-T-T-T-K-A-P-A-K-K-T-T-S-T-K-K-A-T-V-K-K-E-S


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-T-K-Y-R-K-M-M-K-G-R-N-R-G-Y-A-N-R-G-T-E-F-T-F-G-E-F-A-L-K-A-T-E-A-G-R-I-N-S-R-Q-I-E-A-A-R-I-A-L-T-R-F-V-K-R-Q-G-K-T-W-I-R-V-F-P-D-K-P-L-T-K-K-P-L-E-T-R-M-G-K-G-K-G-A-V-E-E-W-V-M-N-I-K-P-G-R-I-I-Y-E-M-A-G-V-S-E-E-M-A-R-E-A-L-T-L-A-M-H-K-L-P-F-K-T-K-F-V-T-R-E-S-Q-N-E-I-Y


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-F-K-R-E-I-Q-G-V-V-V-K-I-A-G-E-K-T-A-S-V-L-V-E-R-K-V-V-H-P-R-Y-R-K-I-V-K-R-F-K-K-Y-L-I-H-D-E-R-N-E-V-K-V-G-D-T-V-V-A-V-E-C-R-P-L-S-K-R-K-S-F-R-L-K-S-V-L-A-T-G-V-E


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-V-K-L-K-I-K-K-G-D-S-V-K-V-I-T-G-D-D-K-G-K-T-G-K-V-L-A-V-Y-P-K-T-L-K-V-V-V-E-G-C-K-I-A-K-K-A-I-K-P-S-E-K-N-P-N-G-G-F-I-N-K-E-M-P-M-D-I-S-N-V-A-K-V-Q-E


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-M-R-L-K-E-K-Y-N-Q-S-I-K-P-A-L-V-K-E-F-D-I-K-N-P-M-L-I-P-V-I-E-K-V-V-I-S-V-G-A-G-E-L-A-K-D-Q-K-V-L-Q-N-V-A-D-T-I-S-L-I-A-G-Q-K-A-V-I-T-K-A-K-K-S-V-A-G-F-K-V-R-E-G-F-P-V-G-V-M-V-T-L-R-K-E-N-M-Y-A-F-L-D-K-L-I-S-I-A-L-P-R-V-K-D-F-R-G-L-S-R-D-G-F-D-G-R-G-N-Y-N-F-G-L-D-E-Q-L-M-F-P-E-V-E-Y-D-K-I-L-R-T-H-G-M-N-I-S-I-V-T-T-A-Q-N-D-K-Q-A-Q-K-L-L-E-L-I-G-V-P-F-T-K-G-K


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-A-A-R-K-P-K-F-K-V-R-A-Y-T-R-C-Q-I-C-G-R-P-H-S-V-Y-R-D-F-G-I-C-R-V-C-L-R-K-M-G-N-E-G-L-I-P-G-L-K-K-A-S-W


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-I-N-D-I-I-S-D-S-L-T-R-I-R-N-A-G-M-R-K-L-E-T-T-K-L-L-H-S-K-V-V-E-A-L-V-G-I-F-Q-A-K-G-Y-I-E-S-F-N-V-I-E-E-D-K-K-K-F-I-N-V-V-L-K-Y-D-E-K-G-K-S-V-I-N-E-L-K-R-I-S-K-P-G-R-R-V-Y-K-G-K-D-E-I-K-R-F-K-N-G-Y-G-T-I-V-V-S-T-S-H-G-V-L-A-N-D-E-A-Y-K-A-G-V-G-G-E-I-L-C-T-I-W


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-R-A-N-V-L-K-R-K-L-T-L-R-I-K-R-K-K-R-I-R-A-K-I-S-G-C-E-N-F-P-R-I-S-V-F-K-S-N-R-T-L-Y-I-Q-A-I-D-D-V-K-A-V-T-L-A-A-V-D-G-R-K-L-G-V-K-A-N-K-E-G-A-K-K-I-A-A-E-F-A-K-T-L-K-V-K-K-I-E-Q-A-V-F-D-R-N-G-Y-V-Y-H-G-V-I-A-A-L-A-E-S-L-R-E-N-G-I-R-L


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-E-K-Y-N-R-E-E-F-E-E-V-I-V-D-I-G-R-V-T-K-V-V-K-G-G-R-R-F-R-F-T-A-L-V-I-V-G-N-R-K-G-L-V-G-V-G-Y-G-K-A-K-E-V-P-D-A-I-R-K-A-V-D-D-A-F-K-N-I-V-E-V-K-T-K-G-S-T-I-A-H-D-V-E-V-K-Y-N-A-S-R-I-L-L-K-P-A-S-E-G-T-G-V-I-A-G-G-S-T-R-P-I-V-E-L-A-G-I-K-D-I-L-T-K-S-L-G-S-N-N-S-A-N-V-V-R-A-T-I-K-A-L-T-M-L-K-G


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-D-F-S-K-M-G-E-L-L-N-Q-V-Q-E-K-A-K-N-I-E-L-E-L-A-N-R-E-F-S-A-K-S-G-A-G-L-V-K-V-S-A-N-G-K-G-E-I-I-D-V-S-I-D-D-S-L-L-E-D-K-E-S-L-Q-I-L-L-I-S-A-I-N-D-V-L-A-M-V-A-Q-N-R-S-S-M-A-N-D-V-L-G-G-F-G-G-M-K-L


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-K-S-A-E-K-R-A-R-Q-T-I-K-K-T-E-R-N-R-F-Y-R-T-R-L-K-N-I-T-K-A-V-R-E-A-A-A-N-G-N-K-N-A-A-N-E-A-L-K-V-A-N-K-S-I-H-A-M-V-S-R-G-F-I-K-K-Q-T-A-S-R-R-V-S-R-L-A-L-L-V-N-K-I-A


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-R-K-I-V-K-K-K-V-V-K-K-N-I-A-K-G-I-V-Y-I-S-A-T-F-N-N-T-M-V-T-V-T-D-E-M-G-N-A-I-A-W-S-S-A-G-G-L-G-F-K-G-S-K-K-S-T-P-Y-A-A-Q-Q-A-V-E-D-A-L-N-K-A-K-E-H-G-I-K-E-V-G-I-K-V-Q-G-P-G-S-G-R-E-T-A-V-K-S-V-G-A-M-E-G-I-K-V-T-F-L-K-D-I-T-P-L-A-H-N-G-C-R-P-P-K-R-R-R-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-D-L-P-K-K-K-R-I-E-Y-G-L-T-Y-I-Y-G-I-G-L-F-T-S-R-K-I-L-D-K-V-G-I-S-Y-D-K-R-V-H-E-L-S-E-D-E-A-A-A-I-R-K-E-I-Q-E-N-Y-M-V-E-G-D-L-R-K-Q-V-A-M-D-I-K-A-L-M-D-L-G-S-F-R-G-L-R-H-R-K-G-L-P-V-R-G-Q-K-T-K-T-N-A-R-T-R-K-G-K-R-K-T-V-G-A-K-S


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-E-I-D-G-T-V-L-E-A-L-P-N-A-N-F-K-V-E-L-D-N-K-H-V-I-L-C-H-I-A-G-K-M-R-M-H-Y-I-R-I-M-P-G-D-K-V-K-V-E-L-T-P-Y-S-L-D-K-G-R-I-T-F-R-Y-K


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-R-V-G-C-D-I-I-A-I-S-R-I-E-K-I-H-S-R-H-G-K-N-F-L-D-K-F-L-N-P-K-E-Q-I-L-I-K-N-P-A-T-L-A-G-L-W-A-A-K-E-A-A-S-K-A-L-G-V-G-I-C-E-L-C-S-F-F-D-I-E-I-S-K-D-E-K-N-A-P-K-L-K-Y-S-Q-K-I-T-K-D-F-N-I-T-Q-T-S-L-S-I-S-H-D-N-G-F-A-I-A-I-V-A-V-V


### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-K-I-A-L-F-G-G-S-F-D-P-P-H-N-G-H-N-S-V-V-L-E-A-L-E-K-L-D-I-D-K-L-I-I-M-P-T-Y-I-N-P-F-K-Q-S-F-S-A-D-E-K-Q-R-F-L-W-V-K-K-L-W-G-H-L-P-K-V-E-I-C-D-F-E-I-R-Q-K-R-P-V-P-S-I-E-S-V-K-Y-L-Y-K-L-Y-N-P-S-K-F-Y-L-L-I-G-A-D-H-L-E-K-L-H-L-W-H-D-F-E-K-L-N-S-L-V-E-F-V-I-A-N-R-N-D-I-G-I-P-K-N-F-K-D-L-K-T-N-K-K-I-A-S-S-F-I-R-D-T-L-N-T-N-E-V-C-E-E-I-K-D-E-V-K-K-Y-Y-E-K-L-Q-K-N


### FUNCTION Might be involved in Fe ### SEQUENCE -M-T-L-N-E-L-K-D-G-Q-K-A-I-I-V-N-L-N-A-H-K-E-L-K-N-R-L-L-S-F-G-F-I-K-N-K-N-L-K-K-I-H-S-S-L-K-N-A-T-I-M-V-E-L-D-T-S-C-V-I-L-R-S-D-E-A-K-T-I-E-V-N-L-I


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-D-K-R-I-E-E-V-A-A-K-A-L-E-K-M-G-N-D-R-Y-R-L-S-L-V-V-A-K-R-A-E-Q-L-A-N-G-A-T-P-L-V-D-F-D-K-N-K-N-K-L-A-D-I-A-L-Y-E-I-A-E-N-K-I-T-L-E-G-L-V-E-T-N-R


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-V-K-G-L-E-K-F-N-E-L-V-E-S-F-A-N-L-P-T-I-G-K-K-T-A-I-R-L-A-Y-H-L-C-I-N-N-Q-I-D-G-M-K-L-A-H-N-I-E-N-A-I-R-F-I-K-P-C-E-Q-C-G-A-L-S-E-N-E-L-C-E-I-C-S-D-K-E-R-N-K-N-I-L-C-I-V-E-S-P-K-D-I-L-T-L-E-E-S-Q-S-Y-N-G-L-Y-F-V-L-D-E-L-N-E-E-K-L-E-K-L-K-Q-I-I-L-K-L-N-I-S-E-L-I-F-A-L-T-H-S-I-N-S-D-A-T-I-F-F-I-E-D-K-F-K-G-L-N-L-T-F-S-K-I-A-Q-G-I-P-S-G-V-N-L-E-N-V-D-L-I-S-L-N-K-A-M-N-F-R-T-K-I


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-W-S-S-P-S-H-W-L-I-I-L-L-I-V-V-L-L-F-G-A-K-K-I-P-E-L-A-K-G-L-G-K-G-I-K-T-F-K-D-E-M-N-N-D-D-E-V-A-K-N-T-Q-K-I-E-E-N-K-N-T-T-N-N-T-N-A-D-A-S-I-D-E-T-K-K-A


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-P-K-T-Q-T-L-E-Q-T-K-L-S-E-P-K-M-Y-K-V-I-L-L-N-D-D-V-T-T-M-D-F-V-I-E-I-L-M-N-I-F-H-Q-N-L-E-K-A-S-Q-T-M-L-E-I-H-H-N-G-S-G-I-C-G-I-Y-T-Q-E-I-A-L-S-K-Q-K-K-V-M-D-A-A-K-L-A-N-F-P-L-Q-A-K-V-E-E-E


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-I-I-A-R-N-K-K-A-L-F-D-Y-S-I-I-E-R-F-E-A-G-I-V-L-K-G-S-E-V-V-A-L-R-A-G-R-A-N-L-K-D-S-F-V-R-I-I-K-N-E-I-F-L-L-N-S-H-I-S-L-L-H-T-T-H-S-F-Y-K-H-E-E-R-G-A-R-K-L-L-M-H-R-K-Q-I-D-K-L-L-G-K-V-S-I-E-G-Y-T-I-V-A-L-D-L-Y-F-N-T-K-N-K-V-K-A-T-L-A-L-A-K-G-K-N-L-H-D-K-R-E-T-L-K-K-K-Q-A-D-L-E-A-R-A-A-M-K-N-Y-K


### FUNCTION Specifically methylates the N7 position of guanine in position 527 of 16S rRNA ### SEQUENCE -M-I-F-K-D-Y-D-F-L-Q-N-Y-D-L-K-N-F-E-E-K-V-K-I-Y-K-E-L-L-S-K-F-N-R-I-H-N-L-T-H-L-K-N-I-D-E-N-I-F-D-S-I-K-I-L-D-F-Y-D-F-S-K-A-K-N-I-A-D-I-G-S-G-A-G-F-P-V-V-F-L-A-F-L-L-Q-S-N-F-H-L-F-E-P-N-P-K-K-A-A-F-L-R-T-L-K-I-E-C-E-L-P-N-L-H-I-Y-K-E-K-V-Q-E-Y-K-N-T-F-K-A-D-I-I-T-S-R-A-L-M-D-V-K-P-L-L-E-I-C-K-N-L-K-D-E-N-T-V-F-I-L-W-K-G-S-E-I-Y-Q-E-L-E-N-I-K-D-Y-E-I-F-E-N-N-L-R-R-Y-C-I-L-K


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-N-F-D-K-F-S-T-N-E-E-F-S-S-V-Y-K-V-G-K-K-W-H-C-E-G-V-I-I-F-Y-L-N-S-Y-E-K-K-I-A-V-V-A-S-K-K-V-G-K-A-V-V-R-N-R-S-K-R-I-L-R-A-L-F-A-K-F-E-R-Y-L-Q-D-G-K-Y-I-F-V-A-K-N-E-I-T-E-L-S-F-S-R-L-E-K-N-L-K-W-G-L-K-K-L-E-C-F-K


### FUNCTION Participates in the translocation of lipoproteins from the inner membrane to the outer membrane Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate ### SEQUENCE -M-K-K-T-F-L-I-F-F-I-F-I-G-Q-L-F-A-L-D-L-N-F-N-T-F-S-S-N-F-T-Q-I-V-K-S-K-N-S-T-L-S-Y-S-G-H-F-I-L-S-K-D-Q-A-Y-W-S-Y-D-T-P-S-K-K-E-I-Y-I-N-K-N-Q-V-T-I-V-E-H-D-L-E-Q-V-I-F-S-H-L-D-N-I-P-N-L-N-E-I-F-K-K-A-S-L-I-D-K-D-K-L-V-A-K-Y-D-N-I-N-Y-T-I-K-L-N-Q-E-Q-I-Q-S-I-S-Y-K-D-E-F-E-N-D-V-I-I-N-L-N-N-Q-I-K-N-P-K-I-N-S-D-V-F-K-A-K-I-P-Q-N-Y-D-I-V-R


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-I-K-L-T-Q-E-E-Q-K-Y-L-L-D-S-I-R-I-I-P-D-F-P-K-K-G-I-I-F-R-D-I-T-T-L-L-N-N-K-E-A-L-N-F-L-L-K-H-L-K-E-R-Y-K-D-Y-N-L-D-F-I-A-G-T-E-S-R-G-F-I-F-A-S-M-I-C-A-K-L-N-L-P-F-V-P-I-R-K-P-G-K-L-P-F-E-T-F-S-C-E-Y-D-L-E-Y-G-S-D-K-V-E-L-H-K-D-A-F-K-N-I-Q-N-A-R-V-L-L-V-D-D-L-I-A-T-G-G-T-A-I-A-S-Y-E-L-I-Q-K-A-G-A-K-C-V-E-A-C-F-L-I-N-L-K-D-L-N-G-A-N-K-L-E-K-L-T-S-V-Y-S-V-L-E-I


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-V-V-G-I-E-G-I-I-T-K-K-E-P-T-F-I-I-V-K-C-A-S-G-L-S-Y-G-I-F-I-S-L-F-C-S-A-K-I-Q-T-Q-E-K-H-E-F-F-I-T-Q-I-I-K-E-D-S-N-K-F-Y-G-F-L-D-K-D-E-Q-K-M-F-E-M-L-L-K-V-N-G-V-G-A-N-T-A-M-A-V-C-S-S-L-D-V-N-S-F-Y-K-A-L-S-L-G-D-E-S-V-L-K-K-V-P-G-I-G-P-K-S-A-K-R-I-I-V-E-L-S-D-T-K-T-K-L-E-N-V-S-D-D-K-S-E-A-L-A-A-L-L-T-L-G-F-K-Q-E-K-I-I-S-V-L-V-S-A-Q-A-T-G-T-S-E-L-I-K-E-A-L-K-K-L-G


### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor  to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-K-V-L-L-G-I-S-G-S-S-S-V-N-L-G-L-K-L-L-K-N-L-E-N-Q-C-E-L-Y-C-I-L-T-Q-G-A-K-L-N-F-K-T-E-N-Q-A-N-L-E-E-I-C-Q-E-N-F-K-Y-T-H-F-L-D-D-K-N-L-S-L-S-V-A-S-G-S-F-G-I-E-K-T-I-I-A-P-C-S-I-S-S-L-A-K-I-H-A-G-F-A-D-T-L-L-M-R-A-A-A-V-A-L-K-E-R-K-K-L-I-L-G-V-R-E-M-P-F-S-T-L-N-L-E-H-M-L-K-L-S-Q-M-G-V-I-I-A-P-P-I-I-A-S-Y-S-K-A-N-N-L-E-Q-M-E-N-F-I-A-G-K-W-L-D-L-L-E-I-K-H-N-L-Y-E-K-W-Q-N-F


### FUNCTION Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis ### SEQUENCE -M-Y-V-V-F-E-G-I-D-C-V-G-K-S-T-Q-I-S-L-L-K-E-I-Y-K-D-A-I-F-T-L-E-P-G-G-T-E-L-G-K-H-L-R-E-I-L-L-N-K-T-H-P-I-N-K-R-A-E-L-L-L-F-L-A-D-R-A-Q-H-F-E-E-I-L-K-T-N-Q-N-K-L-I-I-S-D-R-S-F-I-S-G-M-A-Y-A-K-D-F-E-N-D-L-L-F-A-L-N-S-F-A-L-E-N-F-F-P-Q-K-I-I-F-L-K-G-D-A-N-L-I-Q-E-R-L-S-Q-K-E-L-D-S-I-E-K-R-G-I-E-Y-F-L-S-V-Q-D-K-L-E-K-V-L-H-F-L-K-E-K-I-S-V-E-I-L-T-L-D-A-K-E-S-K-E-K-L-H-Q-Q-I-K-E-F-L-Q


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-K-N-K-Y-I-E-Q-F-E-A-K-Q-I-E-G-K-N-V-P-D-F-R-A-G-D-T-L-K-L-A-I-R-I-K-E-G-D-K-T-R-I-Q-N-F-E-G-I-C-I-A-R-R-G-N-G-V-S-E-T-F-I-V-R-K-I-G-A-N-N-V-G-V-E-R-I-F-P-I-Y-S-E-S-L-E-S-I-T-V-L-R-R-G-R-V-R-R-A-R-L-F-Y-L-R-D-R-R-G-K-A-A-R-I-K-E-L-K-K


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-E-K-D-F-V-Q-V-A-K-L-G-K-T-V-G-L-K-G-Y-V-K-L-H-N-L-S-D-F-S-S-Q-F-K-K-D-A-T-F-F-I-K-N-T-K-E-M-L-K-I-K-H-Y-N-A-N-N-S-T-V-L-F-E-N-Y-E-D-I-E-K-A-K-E-L-T-N-L-I-L-F-Q-S-I-E-K-S-R-Q-T-C-K-L-K-K-D-E-F-F-Y-F-D-I-L-E-C-E-V-F-E-E-D-K-R-L-G-K-V-V-D-I-L-E-T-G-A-S-Y-L-F-E-I-Q-S-D-E-K-W-V-E-K-K-Y-P-K-I-F-F-I-P-Y-L-D-K-F-V-K-N-I-D-I-E-K-R-Q-I-F-C-T-Q-D-A-F-L-I-L-E-N-S


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-A-N-F-I-S-L-K-K-N-E-D-I-L-D-T-I-K-K-Q-Q-K-I-H-S-N-Q-I-V-V-Y-F-R-K-T-N-L-K-N-V-R-L-A-I-S-I-S-K-K-K-F-K-L-A-T-Q-R-N-R-I-R-R-L-I-K-A-W-F-I-A-A-D-I-P-I-K-S-Y-D-I-V-V-L-V-K-P-S-F-I-D-G-S-F-V-L-N-C-N-N-L-K-I-I-L-Q-R-I-I-N-K-E-K-R


### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-S-R-Q-L-V-D-I-A-Y-N-A-I-K-N-N-K-I-Y-N-K-K-P-F-T-F-D-D-I-I-N-E-I-V-K-N-S-N-V-N-L-V-E-V-N-S-Q-L-G-V-L-Y-T-T-L-I-Q-D-T-R-F-I-S-I-G-D-L-E-W-N-L-R-E-R-L-S-L-D-E-I-T-K-I-N-N-A-M-Y-E-V-G-L-Y-K-D-S-D-R-E-E-D-E-H-E-I-V-K-N-D-K-L-T-Q-S-K-E-Q-E-E-S-D-E-V-S-S-L-S-D-F-V-G-Y-E-D-E-D-E-E-F-K-N-N-N-T-S-N-K-D-E-I-E-D-E-E-E-L-E-E-E-E


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-Q-K-S-S-M-L-K-K-E-V-A-I-A-R-R-Q-W-Y-L-V-D-A-T-D-L-V-L-G-R-L-S-V-K-V-A-D-I-L-R-G-K-N-K-V-D-Y-T-P-N-V-D-A-G-D-Y-V-V-V-I-N-S-D-K-V-V-L-T-G-Q-K-A-L-R-E-N-W-Y-N-H-S-H-Y-I-G-G-L-R-T-R-S-G-E-E-M-I-S-K-Y-S-D-E-L-I-R-R-S-V-K-G-M-L-P-K-N-K-L-A-K-Q-I-L-N-K-L-F-I-Y-K-N-D-K-H-P-H-E-A-Q-Q-P-T-I-L-E-L-K-L-K


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-A-L-F-K-I-N-K-G-E-I-M-N-F-V-N-S-T-Q-L-K-T-D-I-P-N-F-D-S-G-D-T-I-I-V-H-N-R-I-V-E-G-K-K-S-R-I-Q-K-F-E-G-V-V-L-R-R-R-G-S-G-S-S-E-T-V-I-V-R-K-E-S-S-G-I-G-V-E-Q-S-F-N-I-H-S-P-L-V-E-K-I-E-V-I-K-Y-G-K-V-R-R-A-Y-I-S-Y-M-R-N-R-S-G-K-S-A-R-I-K-E-L-N-K-Q


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-K-Y-E-I-M-L-V-V-R-G-D-L-D-Q-E-Q-A-N-K-V-A-N-E-L-K-A-T-L-K-N-T-E-V-K-E-N-N-Y-D-G-V-Q-Q-L-A-Y-E-I-N-K-L-K-T-A-Y-R-Y-V-Y-N-F-E-T-T-D-V-S-L-I-N-E-F-R-R-L-A-I-I-N-K-N-V-L-R-H-I-I-I-N-L-E-K-D-Y-G-Y-K-A-T-V-N-T-K-K-V-Q-R-N-E-K-R-A-E-V-Y-A-R-Q-K-E-E-A-E-R-R-A-V-E-R-Q-A-A-Y-E-A-M-K-A-E-R-E-A-A-G-L-P-V-K-E-F-V-K-N-T-N-S-K-R


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-K-V-T-N-N-R-N-R-K-P-R-K-K-V-C-I-L-S-A-K-G-I-E-H-V-D-Y-K-D-V-E-L-L-Q-R-F-I-N-N-N-N-K-I-A-S-R-R-V-T-G-A-S-A-R-M-Q-R-R-I-A-N-A-I-K-R-A-R-F-V-G-L-L-P-Y-V-K-E