### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine  at tRNA wobble positions ### SEQUENCE -M-K-R-I-A-F-V-F-S-T-V-P-H-G-T-A-A-G-R-E-G-L-D-A-L-L-A-T-S-A-L-T-D-D-L-A-V-F-F-I-A-D-G-V-F-Q-L-L-P-G-Q-K-P-D-A-V-L-A-R-D-Y-I-A-T-F-K-L-L-G-L-Y-D-I-E-Q-C-W-V-C-A-A-S-L-R-E-R-G-L-D-P-Q-T-P-F-V-V-E-A-T-P-L-E-A-D-A-L-R-R-E-L-A-N-Y-D-V-I-L-R-F


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine  at tRNA wobble positions ### SEQUENCE -M-L-H-T-L-H-R-S-P-W-L-T-D-F-A-A-L-L-R-L-L-S-E-G-D-E-L-L-L-L-Q-D-G-V-T-A-A-V-D-G-N-R-Y-L-E-S-L-R-N-A-P-I-K-V-Y-A-L-N-E-D-L-I-A-R-G-L-T-G-R-I-S-N-D-I-I-P-I-D-Y-T-D-F-V-R-L-T-V-K-H-S-S-Q-M-A-W


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-D-D-E-V-I-V-L-T-G-K-D-K-G-K-R-G-K-V-K-N-V-L-S-S-G-K-V-I-V-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-L-N-Q-P-G-G-I-V-E-K-E-A-A-I-Q-V-S-N-V-A-I-F-N-A-T-T-G-K-A-D-R-V-G-F-R-F-E-D-G-K-K-V-R-F-F-K-S-N-S-E-T-I-K


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-I-I-K-E-F-R-E-F-A-M-R-G-N-V-V-D-L-A-V-G-V-I-I-G-A-A-F-G-K-I-V-S-S-L-V-A-D-I-I-M-P-P-L-G-L-L-I-G-G-I-D-F-K-Q-F-A-V-T-L-R-E-A-Q-G-D-I-P-A-V-V-M-H-Y-G-V-F-I-Q-N-V-F-D-F-L-I-V-A-F-A-I-F-M-A-I-K-L-I-N-K-L-N-R-K-K-E-E-P-A-A-A-T-P-A-P-T-K-E-E-V-L-L-T-E-I-R-D-L-L-K-E-Q-N-N-R-S


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-R-S-S-A-K-Q-E-E-L-V-K-A-F-K-A-L-L-K-E-E-K-F-S-S-Q-G-E-I-V-A-A-L-Q-E-Q-G-F-D-N-I-N-Q-S-K-V-S-R-M-L-T-K-F-G-A-V-R-T-R-N-A-K-M-E-M-V-Y-C-L-P-A-E-L-G-V-P-T-T-S-S-P-L-K-N-L-V-L-D-I-D-Y-N-D-A-V-V-V-I-H-T-S-P-G-A-A-Q-L-I-A-R-L-L-D-S-L-G-K-A-E-G-I-L-G-T-I-A-G-D-D-T-I-F-T-T-P-A-N-G-F-T-V-K-E-L-Y-E-A-I-L-E-L-F-D-Q-E-L


### FUNCTION Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein ### SEQUENCE -M-Q-E-R-I-K-A-C-F-T-E-S-I-Q-T-Q-I-A-A-A-E-A-L-P-D-A-I-S-R-A-A-M-T-L-V-Q-S-L-L-N-G-N-K-I-L-C-C-G-N-G-T-S-A-A-N-A-Q-H-F-A-A-S-M-I-N-R-F-E-T-E-R-P-S-L-P-A-I-A-L-N-T-D-N-V-V-L-T-A-I-A-N-D-R-L-H-D-E-V-Y-A-K-Q-V-R-A-L-G-H-A-G-D-V-L-L-A-I-S-T-R-G-N-S-R-D-I-V-K-A-V-E-A-A-V-T-R-D-M-T-I-V-A-L-T-G-Y-D-G-G-E-L-A-G-L-L-G-P-Q-D-V-E-I-R-I-P-S-H-R-S-A-R-I-Q-E-M-H-M-L-T-V-N-C-L-C-D-L-I-D-N-T-L-F-P-H-Q-D-V


### FUNCTION Toxic component of a type II toxin-antitoxin ### SEQUENCE -M-D-F-P-Q-R-V-N-G-W-A-L-Y-A-H-P-C-F-Q-E-T-Y-D-A-L-V-A-E-V-E-A-L-K-G-K-D-P-E-N-Y-Q-R-K-A-A-T-K-L-L-A-V-V-H-K-V-I-E-E-H-I-T-V-N-P-S-S-P-A-F-R-H-G-K-S-L-G-S-G-K-N-K-D-W-S-R-V-K-F-G-A-G-R-Y-R-L-F-F-R-Y-S-E-K-E-K-V-I-I-L-G-W-M-N-D-E-N-T-L-R-T-Y-G-K-K-T-D-A-Y-T-V-F-S-K-M-L-K-R-G-H-P-P-A-D-W-E-S-L-T-Q-E-T-E-E-S-H


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-L-S-L-C-Q-S-A-V-E-I-I-Q-R-Q-A-E-Q-H-D-V-K-R-V-T-A-V-W-L-E-I-G-A-L-S-C-V-E-E-S-A-V-R-F-S-F-E-I-V-C-H-G-T-V-A-Q-G-C-D-L-H-I-V-Y-K-P-A-Q-A-W-C-W-D-C-S-Q-V-V-E-I-H-Q-H-D-A-Q-C-P-I-C-H-G-E-R-L-R-V-D-T-G-D-S-L-I-V-K-S-I-E-V-E


### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-S-R-T-I-F-C-T-F-L-Q-R-E-A-E-G-Q-D-F-Q-L-Y-P-G-E-L-G-K-R-I-Y-N-E-I-S-K-E-A-W-A-Q-W-Q-H-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-A-E-H-R-K-L-L-E-Q-E-M-V-N-F-L-F-E-G-K-E-V-H-I-E-G-F-T-P-E-D-K-K


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-I-P-A-E-L-K-Y-S-K-E-H-E-W-L-R-K-E-A-D-G-T-Y-T-V-G-I-T-E-H-A-Q-E-L-L-G-D-M-V-F-V-D-L-P-E-V-G-A-T-V-S-A-G-D-D-C-A-V-A-E-S-V-K-A-A-S-D-I-Y-A-P-V-S-G-E-I-V-A-V-N-D-A-L-S-D-S-P-E-L-V-N-S-E-P-Y-A-G-G-W-I-F-K-I-K-A-S-D-E-S-E-L-E-S-L-L-D-A-T-A-Y-E-A-L-L-E-D-E


### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-Q-P-N-D-I-T-F-F-Q-R-F-Q-D-D-I-L-A-G-R-K-T-I-T-I-R-D-E-S-E-S-H-F-K-T-G-D-V-L-R-V-G-R-F-E-D-D-G-Y-F-C-T-I-E-V-T-A-T-S-T-V-T-L-D-T-L-T-E-K-H-A-E-Q-E-N-M-T-L-T-E-L-K-K-V-I-A-D-I-Y-P-D-Q-T-Q-F-Y-V-I-E-F-K-C-L


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-G-K-L-T-L-L-L-L-A-I-L-V-W-L-Q-Y-S-L-W-F-G-K-N-G-I-H-D-Y-T-R-V-N-N-D-V-A-A-Q-Q-A-T-N-A-K-L-K-A-R-N-D-Q-L-F-A-E-I-D-D-L-N-G-G-Q-E-A-L-E-E-R-A-R-N-E-L-S-M-T-R-P-G-E-T-F-Y-R-L-V-P-D-A-S-K-R-A-Q-S-A-G-Q-N-N-R


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-I-T-L-C-Q-R-A-L-E-L-I-E-Q-Q-A-A-K-H-G-A-K-R-V-T-G-V-W-L-K-I-G-A-F-S-C-V-E-T-S-S-L-A-F-C-F-D-L-V-C-R-G-S-V-A-E-G-C-K-L-H-L-E-E-Q-E-A-E-C-W-C-E-T-C-Q-Q-Y-V-T-L-L-T-Q-R-V-R-R-C-P-L-C-H-G-D-M-L-Q-I-V-A-D-D-G-L-Q-I-R-R-I-E-I-D-Q-E


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-S-K-E-Q-K-T-P-E-G-Q-A-P-E-E-I-I-M-D-Q-H-E-E-I-E-A-V-E-P-E-A-S-A-E-Q-V-D-P-R-D-E-K-I-A-N-L-E-A-Q-L-A-E-A-Q-T-R-E-R-D-G-I-L-R-V-K-A-E-M-E-N-L-R-R-R-T-E-L-D-I-E-K-A-H-K-F-A-L-E-K-F-I-N-E-L-L-P-V-I-D-S-L-D-R-A-L-E-V-A-D-K-A-N-P-D-M-S-A-M-V-E-G-I-E-L-T-L-K-S-M-L-D-V-V-R-K-F-G-V-E-V-I-A-E-T-N-V-P-L-D-P-N-V-H-Q-A-I-A-M-V-E-S-D-D-V-A-P-G-N-V-L-G-I-M-Q-K-G-Y-T-L-N-G-R-T-I-R-A-A-M-V-T-V-A-K-A-K-A


### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-T-G-I-Q-I-T-K-A-A-N-D-D-L-L-N-S-F-W-L-L-D-S-E-K-G-E-A-R-C-I-V-A-K-A-G-F-A-E-D-E-V-V-A-V-S-K-L-G-D-I-E-Y-R-E-V-P-V-E-V-K-P-E-V-R-V-E-G-G-Q-H-L-N-V-N-V-L-R-R-E-T-L-E-D-A-V-K-H-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-A-R-T-F-T-E-S-L


### FUNCTION Exporter of O-acetylserine  and cysteine ### SEQUENCE -M-T-P-T-L-L-S-A-F-W-T-Y-T-L-I-T-A-M-T-P-G-P-N-N-I-L-A-L-S-S-A-T-S-H-G-F-R-Q-S-T-R-V-L-A-G-M-S-L-G-F-L-I-V-M-L-L-C-A-G-I-S-F-S-L-A-V-I-D-P-A-A-V-H-L-L-S-W-A-G-A-A-Y-I-V-W-L-A-W-K-I-A-T-S-P-T-K-E-D-G-L-Q-T-K-P-I-S-F-W-A-S-F-A-L-Q-F-V-N-V-K-I-I-L-Y-G-V-T-A-L-S-T-F-V-L-P-Q-T-Q-A-L-S-W-V-V-G-V-S-V-L-L-A-M-I-G-T-F-G-N-V-C-W-A-L-A-G-H-L-F-Q-R-L-F-R-Q-Y-G-R-Q-L-N-I-V-L-A-L-L-L-V-Y-C-A-V-R-I-F-Y


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-L-G-L-G-T-D-I-V-E-I-A-R-I-E-A-V-I-A-R-S-G-E-R-L-A-R-R-V-L-S-D-N-E-W-E-I-W-K-T-H-H-Q-P-V-R-F-L-A-K-R-F-A-V-K-E-A-A-A-K-A-F-G-T-G-I-R-N-G-L-A-F-N-Q-F-E-V-F-N-D-E-L-G-K-P-R-L-R-L-W-G-E-A-L-K-L-A-E-K-L-G-V-V-N-M-H-V-T-L-A-D-E-R-H-Y-A-C-A-T-V-I-I-E-S


### FUNCTION May function as iron donor in the assembly of iron-sulfur clusters ### SEQUENCE -M-G-L-K-W-T-D-S-R-E-I-G-E-A-L-Y-D-A-Y-P-D-I-D-P-K-T-V-R-F-T-D-M-H-Q-W-I-C-A-L-E-D-F-D-D-D-P-Q-A-S-N-E-K-I-L-E-A-I-L-L-V-W-L-D-E-A-E


### FUNCTION Catalyzes the dephosphorylation of heptose of the outer membrane lipopolysaccharide core ### SEQUENCE -M-L-A-F-C-R-S-S-L-K-S-K-K-Y-F-I-I-L-L-A-L-A-A-I-A-G-L-G-T-H-A-A-W-S-S-N-G-L-P-R-I-D-N-K-T-L-A-R-L-A-Q-Q-H-P-V-V-V-L-F-R-H-A-E-R-C-D-R-S-T-N-Q-C-L-S-D-K-T-G-I-T-V-K-G-T-Q-D-A-R-E-L-G-N-A-F-S-A-D-I-P-D-F-D-L-Y-S-S-N-T-V-R-T-I-Q-S-A-T-W-F-S-A-G-K-K-L-T-V-D-K-R-F-L-Q-C-G-N-E-I-Y-S-A-I-K-D-L-Q-R-K-A-P-D-K-N-I-V-I-F-T-H-N-H-C-L-T-Y-I-A-K-D-K-R-D-A-T-F-K-P-D-Y-L-D-G-L-V-M-H-V-E-K-G-K-V-Y-L-D-G-E-F-V-N-H


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-F-T-I-N-A-E-V-R-K-E-Q-G-K-G-A-S-R-R-L-R-A-A-N-K-F-P-A-I-I-Y-G-G-K-E-A-P-L-A-V-E-L-D-H-D-K-V-M-N-M-Q-V-K-A-E-F-Y-S-E-V-L-T-I-V-V-D-G-K-E-I-K-V-K-A-Q-D-V-Q-R-H-P-Y-K-P-K-L-L-H-I-D-F-V-R-A


### FUNCTION Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD As a transcriptional regulator, acts as an anti-FlhDC factor ### SEQUENCE -M-N-N-A-P-H-L-Y-F-A-W-Q-Q-L-V-E-K-S-Q-L-M-L-R-L-A-T-E-E-Q-W-D-E-L-I-A-S-E-M-A-Y-V-N-A-V-Q-E-I-A-H-L-T-E-E-V-A-P-S-T-T-M-Q-E-Q-L-R-P-M-L-H-L-I-L-D-N-E-S-K-V-K-Q-L-L-Q-I-R-M-D-E-L-A-K-L-V-G-Q-S-S-V-Q-K-S-V-L-S-A-Y-G-D-Q-G-G-F-V-L-A-P-Q-D-N-L-F


### FUNCTION Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors In its active ### SEQUENCE -M-A-D-K-E-L-K-F-L-V-V-D-D-F-S-T-M-R-R-I-V-R-N-L-L-K-E-L-G-F-N-N-V-E-E-A-E-D-G-L-D-A-L-N-K-L-Q-A-G-G-Y-G-F-V-I-S-D-W-N-M-P-N-M-D-G-L-E-L-L-K-T-I-R-A-D-G-A-M-S-A-L-P-V-L-M-V-T-A-E-A-K-K-E-N-I-I-A-A-A-Q-A-G-A-S-G-Y-V-V-K-P-F-T-A-A-T-L-E-E-K-L-N-K-I-F-E-K-L-G-M


### FUNCTION PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP ### SEQUENCE -M-K-K-F-R-W-V-A-L-V-V-V-V-L-A-C-L-L-L-W-A-Q-V-F-N-M-M-C-D-Q-D-V-Q-F-F-S-G-I-C-A-I-N-Q-F-I-P-W


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-N-I-T-A-T-V-L-L-A-F-G-M-S-M-D-A-F-A-A-S-I-G-K-G-A-T-L-H-K-P-K-F-S-E-A-L-R-T-G-L-I-F-G-A-V-E-T-L-T-P-L-I-G-W-G-M-G-M-L-A-S-R-F-V-L-E-W-N-H-W-I-A-F-V-L-L-I-F-L-G-G-R-M-I-I-E-G-F-R-G-A-D-D-E-D-E-E-P-R-R-R-H-G-F-W-L-L-V-T-T-A-I-A-T-S-L-D-A-M-A-V-G-V-G-L-A-F-L-Q-V-N-I-I-A-T-A-L-A-I-G-C-A-T-L-I-M-S-T-L-G-M-M-V-G-R-F-I-G-S-I-I-G-K-K-A-E-I-L-G-G-L-V-L-I-G-I-G-V-Q-I-L-W-T-H-F-H-G


### FUNCTION Probably mediates the hydrolysis of some nucleoside diphosphate derivatives ### SEQUENCE -M-E-Y-R-S-L-T-L-D-D-F-L-S-R-F-Q-L-L-R-P-Q-I-N-R-E-T-L-N-H-R-Q-A-A-V-L-I-P-I-V-R-R-P-Q-P-G-L-L-L-T-Q-R-S-I-H-L-R-K-H-A-G-Q-V-A-F-P-G-G-A-V-D-D-T-D-T-S-V-I-A-A-A-L-R-E-A-E-E-E-V-A-I-P-P-S-A-V-E-V-I-G-V-L-P-P-V-D-S-V-T-G-Y-Q-V-T-P-V-V-G-I-I-P-P-D-L-P-Y-R-A-S-E-D-E-V-S-A-V-F-E-M-P-L-A-Q-A-L-H-L-G-R-Y-H-P-L-D-I-Y-R-R-G-D-S-H-R-V-W-L-S-W-Y-E-Q-Y-F-V-W-G-M-T-A-G-I-I-R-E-L-A-L-Q-I-G-V-K-P


### FUNCTION Activates the cell division inhibited by chromosomal DNA over-replication ### SEQUENCE -M-K-K-P-L-R-Q-Q-N-R-Q-I-I-S-Y-V-P-R-T-E-P-A-P-P-E-H-A-I-K-M-D-S-F-R-D-V-W-M-L-R-G-K-Y-V-A-F-V-L-M-G-E-S-F-L-R-S-P-A-F-T-V-P-E-S-A-Q-R-W-A-N-Q-I-R-Q-E-N-E-V-E-E


### FUNCTION Participates in cysteine desulfuration mediated by SufS Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process ### SEQUENCE -M-A-L-L-P-D-K-E-K-L-L-R-N-F-L-R-C-A-N-W-E-E-K-Y-L-Y-I-I-E-L-G-Q-R-L-P-E-L-R-D-E-D-K-S-P-Q-N-S-I-Q-G-C-Q-S-Q-V-W-I-V-M-R-Q-N-A-Q-G-I-I-E-L-Q-G-D-S-D-A-A-I-V-K-G-L-I-A-V-V-F-I-L-Y-D-Q-M-T-P-Q-D-I-V-N-F-D-V-R-P-W-F-E-K-M-A-L-T-Q-H-L-T-P-S-R-S-Q-G-L-E-A-M-I-R-A-I-R-A-K-A-A-A-L-S


### FUNCTION Catalyzes the excretion of spermidine ### SEQUENCE -M-Y-I-Y-W-I-L-L-G-L-A-V-A-T-E-I-T-G-T-L-S-M-K-W-A-S-V-S-E-G-N-G-G-F-I-L-M-L-V-M-I-S-L-S-Y-I-F-L-S-F-A-V-K-K-I-A-L-G-V-A-Y-A-L-W-E-G-I-G-I-L-F-I-T-L-F-S-V-L-L-F-D-E-S-L-S-L-M-K-I-A-G-L-T-T-L-V-A-G-I-V-L-I-K-S-G-T-R-K-A-R-K-P-E-L-E-V-N-H-G-A-V


### FUNCTION Catalyzes the excretion of spermidine ### SEQUENCE -M-A-Q-F-E-W-V-H-A-A-W-L-A-L-A-I-V-L-E-I-I-A-N-V-F-L-K-F-S-D-G-F-R-R-K-I-F-G-L-L-S-L-A-A-V-L-A-A-F-S-A-L-S-Q-A-V-K-G-I-D-L-S-V-A-Y-A-L-W-G-G-F-G-I-A-A-T-L-A-A-G-W-I-L-F-G-Q-R-L-N-R-K-G-W-I-G-L-V-L-L-L-A-G-M-I-M-V-K-L-A


### FUNCTION Antitoxin component of a type II type II toxin-antitoxin ### SEQUENCE -M-L-W-T-Y-D-M-M-S-F-Q-K-I-Y-S-P-T-Q-L-A-N-A-M-K-L-V-R-Q-Q-N-G-W-T-Q-S-E-L-A-K-K-I-G-I-K-Q-A-T-I-S-N-F-E-N-N-P-D-N-T-S-L-T-T-F-F-K-I-L-Q-S-L-E-L-S-M-T-L-C-D-A-K-N-A-S-P-E-A-A-E-Q-Q-D-L-E-W


### FUNCTION Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions ### SEQUENCE -M-H-A-T-T-V-K-N-K-I-T-Q-R-D-N-Y-K-E-I-M-S-V-I-V-V-V-L-L-L-T-L-T-L-I-A-I-F-S-A-I-D-Q-L-G-I-S-E-M-G-R-I-A-R-D-L-T-H-F-I-I-N-S-L-Q-D


### FUNCTION Regulates expression of genes involved in acid-resistance and biofilm formation May be a non-specific DNA-binding protein that binds genes and/or intergenic regions via a geometric recognition ### SEQUENCE -M-L-E-D-T-T-I-H-N-A-I-S-D-K-A-L-S-S-Y-F-R-S-S-G-N-L-L-E-E-E-S-A-V-L-G-Q-A-V-T-N-L-M-L-S-G-D-N-V-N-N-K-N-I-I-L-S-L-I-H-S-L-E-T-T-S-D-I-L-K-A-D-V-I-R-K-T-L-E-I-V-L-R-Y-T-A-D-D-M


### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation ### SEQUENCE -M-K-W-I-V-I-D-T-V-I-Q-P-S-C-G-I-S-F-S-V-I-W-S-K-I-K-L-I-I-W-Y-Q-S-D-A-F-L-P-P-E-S-I-F-T-L-T-H-T-G-I-M-L-N-N-K-V-L-P-V-T-I-Y-N-V-V-P-F-N-K-T-F-W-N-L-I-K-N-S-Q-E-C-P-T-N-T-D-N-V-L-N-E-C-F-N-N-R-C-T-L-Q-I-C-P-Y-G-L-K-Q-Q-S-P


### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-P-K-L-I-L-A-S-T-S-P-W-R-R-A-L-L-E-K-L-Q-I-S-F-E-C-A-A-P-E-V-D-E-T-P-R-S-D-E-S-P-R-Q-L-V-L-R-L-A-Q-E-K-A-Q-S-L-A-S-C-Y-P-D-H-L-I-I-G-S-D-Q-V-C-V-L-D-G-E-I-T-G-K-P-L-T-E-E-N-A-R-L-Q-L-R-K-A-S-G-N-I-V-T-F-Y-T-G-L-A-L-F-N-S-A-N-G-H-L-Q-T-E-V-E-P-F-D-V-H-F-R-H-L-S-E-A-E-I-D-N-Y-V-R-K-E-H-P-L-H-C-A-G-S-F-K-S-E-G-F-G-I-T-L-F-E-R-L-E-G-R-D-P-N-T-L-V-G-L-P-L-I-A-L-C-Q-M-L-R-R-E-G-K-N-P-L-M-G


### FUNCTION May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted ### SEQUENCE -M-N-E-A-V-S-P-G-A-L-S-T-L-F-T-D-A-R-T-H-N-G-W-R-E-T-P-V-S-D-E-T-L-R-E-I-Y-A-L-M-K-W-G-P-T-S-A-N-C-S-P-T-R-I-V-F-I-R-T-A-E-G-K-E-R-L-R-P-A-L-S-S-G-N-L-Q-K-T-L-T-A-P-V-T-A-I-V-A-W-D-S-E-F-Y-E-R-L-P-Q-L-F-P-H-G-D-A-R-S-W-F-T-S-S-P-Q-L-A-E-E-T-A-F-R-N-S-S-M-Q-A-A-Y-L-I-V-A-C-R-A-L-G-L-D-T-G-P-M-S-G-F-D-R-Q-Y-V-D-D-A-F-F-A-G-S-T-L-K-S-N-L-L-I-N-I-G-Y-G-D-S-S-K-L-F-A-R-L-P-R-L-S-F-E-E-A-C-G-L-L


### FUNCTION Involved in the biogenesis of TorA Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor ### SEQUENCE -M-T-T-L-T-A-Q-Q-I-A-C-V-Y-A-W-L-A-Q-L-F-S-R-E-L-D-D-E-Q-L-T-Q-I-A-S-A-Q-M-A-E-W-F-S-L-L-K-S-E-P-P-L-T-A-A-V-N-G-L-E-N-S-I-A-T-L-T-V-R-D-D-A-R-L-E-L-A-A-D-F-C-G-L-F-L-M-T-D-K-Q-A-A-L-P-Y-A-S-A-Y-K-Q-D-E-Q-E-I-K-R-L-L-V-E-A-G-M-E-T-S-G-N-F-N-E-P-A-D-H-L-A-I-Y-P-E-L-L-S-H-L-H-F-S-L-G-E-G-T-V-P-A-R-R-I-D-G-L-R-Q-K-T-L-T-A-L-R-E-W-L-P-E-F-A-A-R-C-R-Q-Y-D-R-F-G-F-Y-A-A-L-S-Q-L-L-L-V-L-V-E-C-D-Y-Q-K-R


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine ### SEQUENCE -M-L-I-F-E-G-K-E-I-E-T-D-T-E-G-Y-L-K-E-S-S-Q-W-S-E-P-L-A-V-V-I-A-E-N-E-G-I-A-L-S-P-E-H-W-E-V-V-R-F-V-R-D-F-Y-L-E-F-N-T-S-P-A-I-R-M-L-V-K-A-M-A-N-K-F-G-E-E-K-G-N-S-R-Y-L-Y-R-L-F-P-K-G-P-A-K-Q-A-T-K-I-A-G-L-P-K-P-V-K-C-I


### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-E-L-T-T-R-T-L-P-S-R-K-H-I-A-L-V-A-H-D-H-C-K-Q-M-L-M-S-W-V-E-R-H-Q-P-L-L-E-Q-H-V-L-Y-A-T-G-T-T-G-N-L-I-S-R-A-T-G-M-N-V-N-A-M-L-S-G-P-M-G-G-D-Q-Q-V-G-A-L-I-S-E-G-K-I-D-V-L-I-F-F-W-D-P-L-N-A-V-P-H-D-P-D-V-K-A-L-L-R-L-A-T-V-W-N-I-P-V-A-T-N-V-A-T-A-D-F-I-I-Q-S-P-H-F-N-D-A-V-D-I-L-I-P-D-Y-Q-R-Y-L-A-D-R-L-K


### FUNCTION Component of the SOS system and an inhibitor of cell division Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments In the presence of GTP, binds a polymerization-competent form of FtsZ in a 11 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division ### SEQUENCE -M-Y-T-S-G-Y-A-H-R-S-S-S-F-S-S-A-A-S-K-I-A-R-V-S-T-E-N-T-T-A-G-L-I-S-E-V-V-Y-R-E-D-Q-P-M-M-T-Q-L-L-L-L-P-L-L-Q-Q-L-G-Q-Q-S-R-W-Q-L-W-L-T-P-Q-Q-K-L-S-R-E-W-V-Q-A-S-G-L-P-L-T-K-V-M-Q-I-S-Q-L-S-P-C-H-T-V-E-S-M-V-R-A-L-R-T-G-N-Y-S-V-V-I-G-W-L-A-D-D-L-T-A-E-E-H-A-E-L-V-D-A-A-N-E-G-N-A-M-G-F-I-M-R-P-V-S-A-S-S-H-A-T-R-Q-L-S-G-L-K-I-H-S-N-L-Y-H


### FUNCTION Required for spatial organization of the terminus region of the chromosome  during the cell cycle Prevents early segregation of duplicated Ter macrodomains during cell division Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain ### SEQUENCE -M-K-Y-Q-Q-L-E-N-L-E-S-G-W-K-W-K-Y-L-V-K-K-H-R-E-G-E-L-I-T-R-Y-I-E-A-S-A-A-Q-E-A-V-D-E-L-L-S-L-E-N-E-P-V-L-V-N-G-W-I-D-K-H-M-N-P-E-L-V-N-R-M-K-Q-T-I-R-A-R-R-K-R-H-F-N-A-E-H-Q-H-T-R-K-K-S-I-D-L-E-F-I-V-W-Q-R-L-A-G-L-A-Q-R-R-G-K-T-L-S-E-T-I-V-Q-L-I-E-D-A-E-N-K-E-K-Y-A-N-K-M-S-S-L-K-Q-D-L-Q-A-L-L-G-K-E


### FUNCTION Part of the high-affinity ATP-driven potassium transport  system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-R-G-L-R-P-A-L-S-T-F-L-F-L-L-L-I-T-G-G-V-Y-P-L-L-T-T-A-L-G-Q-W-W-F-P-W-Q-A-N-G-S-L-I-R-E-G-D-T-V-R-G-S-A-L-I-G-Q-N-F-T-G-N-G-Y-F-H-G-R-P-S-A-T-A-E-M-P-Y-N-P-Q-A-S-G-G-S-N-L-A-V-S-N-P-E-L-D-K-Q-I-A-A-R-V-A-A-L-R-A-A-N-P-D-A-S-T-N-V-P-V-E-L-V-T-A-S-A-S-G-L-D-N-N-I-T-P-Q-A-A-A-W-Q-I-P-R-V-A-K-A-R-N-L-S-V-E-Q-L-T-Q-L-I-A-K-Y-S-Q-Q-P-L-V-K-Y-I-G-Q-P-V-V-N-I-V-E-L-N-L-A-L-D-K-L-D-E


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-Q-V-I-L-D-L-Q-L-A-C-E-D-N-S-G-L-P-E-E-S-Q-F-Q-T-W-L-N-A-V-I-P-Q-F-Q-E-E-S-E-V-T-I-R-V-V-D-T-A-E-S-H-S-L-N-L-T-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-V-P-P-G-M-E-M-S-L-L-G-D-L-V-I-C-R-Q-V-V-E-K-E-A-Q-E-Q-G-K-P-L-E-A-H-W-A-H-M-V-V-H-G-S-L-H-L-L-G-Y-D-H-I-E-D-D-E-A-E-E-M-E-A-I-E-T-E-I-M-L-A-L-G-Y-E-D-P-Y-I-A-E-K-E


### FUNCTION Transfers 2- of the citrate lyase to yield holo-acyl carrier protein ### SEQUENCE -M-H-L-L-P-E-L-A-S-H-H-A-V-S-I-P-E-L-L-V-S-R-D-E-R-Q-A-R-Q-H-A-W-L-K-R-H-P-V-P-L-V-S-F-T-V-V-A-P-G-P-I-K-D-S-E-V-T-R-R-I-F-N-H-G-V-T-A-L-R-A-L-A-A-K-Q-G-W-Q-I-Q-E-Q-A-A-L-V-S-A-S-G-P-E-G-M-L-S-I-A-A-P-A-R-D-L-K-L-A-T-I-E-L-E-H-S-H-P-L-G-R-L-W-D-I-D-V-L-T-P-E-G-D-I-L-S-R-R-D-Y-S-L-P-P-R-R-C-L-L-C-E-Q-S-A-A-V-C-A-R-G-K-T-H-Q-L-T-D-L-L-N-R-M-E-A-L-L-N-D-V-D-A-C-N-V-N


### FUNCTION Catalyzes the catabolism of the allantoin degradation intermediate -ureidoglycolate, generating urea and glyoxylate Involved in the anaerobic utilization of allantoin as sole nitrogen source Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate ### SEQUENCE -M-K-L-Q-V-L-P-L-S-Q-E-A-F-C-A-Y-G-D-V-I-E-T-Q-K-R-D-F-F-H-I-N-N-G-L-V-E-R-Y-H-D-L-A-L-V-E-I-L-E-Q-D-R-T-L-I-S-I-N-R-A-Q-P-A-N-L-P-L-T-I-H-E-L-E-R-H-P-L-G-T-Q-A-F-I-P-M-K-G-E-V-F-V-V-V-V-A-L-G-D-D-K-P-D-L-S-T-L-R-A-F-I-T-N-G-E-Q-G-V-N-Y-H-R-N-V-W-H-H-P-L-F-A-W-Q-R-V-T-D-F-L-T-I-D-R-G-G-S-D-N-C-D-V-E-S-I-P-E-Q-E-L-C-F-A


### FUNCTION Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP ### SEQUENCE -M-N-F-L-A-H-L-H-L-A-H-L-A-E-S-S-L-S-G-N-L-L-A-D-F-V-R-G-N-P-E-E-S-F-P-P-D-V-V-A-G-I-H-M-H-R-R-I-D-V-L-T-D-N-L-P-E-V-R-E-A-R-E-W-F-R-N-E-T-R-R-V-A-P-I-T-L-D-V-M-W-D-H-F-L-S-R-H-W-S-Q-L-S-P-D-F-P-L-Q-E-F-T-C-Y-A-R-E-Q-V-M-T-I-L-P-D-S-P-Q-R-F-I-N-L-N-N-Y-L-W-S-E-Q-W-L-V-R-Y-R-D-M-D-F-I-Q-S-V-L-N-G-M-A-S-R-R-P-R-L-D-A-L-R-D-S-W-Y-D-L-D-A-H-Y-D-A-L-E-T-R-F-W-Q-F-Y-P-R-M-M-E-Q-A-S-R-K-A-L


### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway ### SEQUENCE -M-K-N-L-I-A-E-L-L-F-K-L-A-Q-K-E-E-E-S-K-E-L-C-A-Q-V-E-A-L-E-I-I-V-T-A-M-L-R-N-M-A-Q-N-D-Q-Q-R-L-I-D-Q-V-E-G-A-L-Y-E-V-K-P-D-A-S-I-P-D-D-D-T-E-L-L-R-D-Y-V-K-K-L-L-R-H-P-R-Q


### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-L-G-M-Q-S-I-R-R-R-Q-L-I-D-A-T-L-E-A-I-N-E-V-G-M-H-D-A-T-I-A-Q-I-A-R-R-A-G-V-S-T-G-I-I-S-H-Y-F-R-D-K-N-G-L-L-E-A-T-M-R-D-I-T-S-Q-L-R-D-A-V-L-N-R-L-H-A-L-P-Q-G-S-A-E-R-R-L-Q-A-I-V-G-G-N-F-D-E-T-Q-V-S-S-A-A-M-K-A-W-L-A-F-W-A-S-S-M-H-Q-P-M-L-Y-R-L-Q-Q-V-S-S-R-R-L-L-S-N-L-V-S-E-F-R-R-E-L-P-R-Q-Q-A-Q-E-A-G-Y-G-L-A-A-L-I-D-G-L-W-L-R-A-A-L-S-G-K-P-L-D-K-P-L-A-H-S-L-T-R-H-F-I-T-Q-H-L-P-T-D


### FUNCTION Part of the ecpRABCDE operon, which encodes the Ecoli common pilus ### SEQUENCE -M-T-W-Q-N-D-Y-S-R-D-Y-E-V-K-N-H-M-E-C-Q-N-R-S-D-K-Y-I-W-S-P-H-D-A-Y-F-Y-K-G-L-S-E-L-I-V-D-I-D-R-L-I-Y-L-S-L-E-K-I-R-K-D-F-V-F-I-N-L-N-T-D-S-L-T-E-F-I-N-R-D-N-E-W-L-S-A-V-K-G-K-Q-V-V-L-I-A-A-R-K-S-E-A-L-A-N-Y-W-Y-Y-N-S-N-I-R-G-V-V-Y-A-G-L-S-R-D-I-R-K-E-L-A-Y-V-I-N-G-R-F-L-R-K-D-I-K-K-D-K-I-T-D-R-E-M-E-I-I-R-M-T-A-Q-G-M-L-P-K-S-I-A-R-I-E-N-C-S-V-K-T-V-Y-T-H-R-R-N-A-E-A-K-L-Y-S-K-L-Y-K-L-V-Q


### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-T-L-P-S-G-H-P-K-S-R-L-I-K-K-F-T-A-L-G-P-Y-I-R-E-G-K-C-E-D-N-R-F-F-F-D-C-L-A-V-C-V-N-V-K-P-A-P-E-V-R-E-F-W-G-W-W-M-E-L-E-A-Q-E-S-R-F-T-Y-S-Y-Q-F-G-L-F-D-K-A-G-D-W-T-S-V-R-I-K-D-A-E-V-V-E-R-L-E-H-T-L-R-E-F-H-E-K-L-R-E-L-L-A-T-L-N-L-K-L-E-P-A-D-D-F-R-D-E-P-V-K-L-T-A


### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-S-E-T-I-T-V-N-C-P-T-C-G-K-T-V-V-W-G-E-I-S-P-F-R-P-F-C-S-K-R-C-Q-L-I-D-L-G-E-W-A-A-E-E-K-R-I-P-S-S-S-D-L-S-E-S-D-D-W-S-E-E-P-K-Q


### FUNCTION Overproduction of CaiE stimulates the activity of CaiB and CaiD ### SEQUENCE -M-S-Y-Y-A-F-E-G-L-I-P-V-V-H-P-T-A-F-V-H-P-S-A-V-L-I-G-D-V-I-V-G-A-G-V-Y-I-G-P-L-A-S-L-R-G-D-Y-G-R-L-I-V-Q-A-G-A-N-I-Q-D-G-C-I-M-H-G-Y-C-D-T-D-T-I-V-G-E-N-G-H-I-G-H-G-A-I-L-H-G-C-V-I-G-R-D-A-L-V-G-M-N-S-V-I-M-D-G-A-V-I-G-E-E-S-I-V-A-A-M-S-F-V-K-A-G-F-R-G-E-K-R-Q-L-L-M-G-T-P-A-R-A-V-R-S-V-S-D-D-E-L-H-W-K-R-L-N-T-K-E-Y-Q-D-L-V-G-R-C-H-A-A-L-H-E-T-Q-P-L-R-Q-M-E-E-N-R-P-R-L-Q-G-T-T-D-V-T-P-K-R


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-Q-Y-E-L-M-I-I-L-D-P-S-Q-D-E-R-T-V-A-P-S-L-D-K-F-L-E-V-V-R-K-D-K-G-D-V-V-K-V-D-V-W-G-K-R-R-L-A-Y-P-I-N-K-K-E-E-G-I-Y-A-V-I-D-L-K-C-E-S-A-T-V-L-E-L-D-R-V-L-N-L-N-D-G-V-L-R-T-K-V-L-R-L-D-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-I-L-T-A-A-V-E-N-L-G-V-A-G-D-I-V-E-V-K-D-G-Y-G-R-N-L-L-L-P-R-G-L-A-I-P-A-T-P-G-A-E-K-Q-I-E-G-I-K-R-A-Q-E-A-R-A-I-R-D-L-D-H-A-R-E-V-K-A-Q-L-E-A-L-E-G-V-K-V-A-V-R-T-S-E-S-G-K-L-F-G-S-V-K-A-D-D-I-V-D-A-V-K-A-A-G-G-P-N-L-D-K-R-A-I-V-L-P-K-N-L-V-K-T-T-G-K-Y-Q-V-E-A-K-I-H-E-G-I-V-S-R-V-K-F-E-V-V-A-A


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-T-V-R-P-I-V-I-H-G-D-P-V-L-H-N-P-T-R-E-V-T-E-P-I-S-E-L-Q-E-L-I-A-D-M-Y-E-T-M-E-V-A-N-G-V-G-L-A-A-N-Q-I-G-V-S-K-R-I-F-V-F-N-C-P-D-D-E-G-T-M-H-R-G-C-F-I-N-P-V-L-E-T-S-E-I-P-E-T-M-P-A-D-D-G-S-D-E-E-G-C-L-S-V-P-G-E-G-F-P-T-G-R-A-D-W-A-K-V-T-G-L-N-E-D-G-E-E-W-S-M-E-G-T-G-F-L-A-R-C-F-Q-H-E-V-G-H-L-D-G-V-V-Y-T-D-T-L-I-G-R-W-K-R-L-A-K-K-T-I-K-A-N-G-W-T-E-P-G-L-T-W-T-P-G-V-D-E-D-P-F-G-H-D-V


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Q-V-S-I-P-V-C-Y-P-C-P-S-F-P-Q-T-R-P-F-A-G-D-G-R-K-F-G-R-V-D-S-G-F-M-P-K-L-W-E-G-L-S-V-G-A-G-A-A-V-G-A-C-A-R-L-A-L-T-M-Q-F-G-E-G-L-W-P-I-L-A-I-N-M-L-G-S-F-L-M-G-R-Y-R-P-G-P-F-W-G-T-G-V-L-G-G-F-T-T-F-S-A-F-A-V-V-L-V-D-V-P-L-P-H-A-V-A-Y-L-T-V-T-V-V-S-C-V-A-A-W-L-M-G-N-R-W-S-A


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-C-S-S-P-S-A-P-T-A-E-P-D-V-E-M-D-V-H-T-V-S-S-E-N-L-P-W-L-C-I-V-W-D-D-P-V-N-L-M-S-Y-V-T-Y-V-F-Q-T-V-L-G-Y-S-R-K-R-A-N-E-L-M-M-Q-V-H-T-E-G-K-A-V-V-S-S-G-E-K-D-K-V-E-G-D-V-K-K-L-H-V-A-G-L-W-A-T-M-Q-Q-A-G


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-S-I-G-T-D-L-V-H-I-P-A-F-A-D-Q-L-A-Q-P-G-S-S-F-M-D-V-F-G-A-G-E-R-R-L-A-S-R-R-A-G-N-R-N-A-E-H-L-A-G-R-W-A-A-K-E-A-F-I-K-A-W-S-Q-A-I-Y-G-Q-P-P-V-I-P-E-E-D-V-Q-W-A-L-I-E-V-R-A-D-R-W-G-R-V-A-L-D-I-A-P-S-L-D-T-Q-V-R-E-S-I-G-D-Y-T-T-S-L-S-I-S-H-D-G-D-Y-A-T-A-V-C-V-L-S-Y-A-V-A-T-E-N-R


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-D-N-L-N-M-T-A-P-G-A-G-T-G-Y-S-G-D-I-F-D-R-L-L-R-E-R-I-I-F-L-G-S-Q-V-D-D-E-I-A-N-K-L-C-A-Q-I-L-L-L-S-A-E-D-P-T-R-D-I-S-L-Y-I-N-S-P-G-G-S-V-T-A-G-M-A-I-Y-D-T-M-K-Y-S-P-C-D-I-A-T-Y-G-M-G-L-A-A-S-M-G-Q-F-L-L-S-G-G-T-P-G-K-R-Y-A-L-P-H-A-R-I-M-M-H-Q-P-S-A-G-V-G-G-T-A-A-D-I-A-I-Q-A-E-Q-F-A-Q-T-K-R-E-M-A-K-L-I-A-E-H-T-G-Q-T-F-E-Q-V-T-K-D-S-D-R-D-R-W-F-T-A-E-Q-A-K-E-Y-G-L-V-D-H-V-I-T-L-A-E-G-P-I-S-N


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-K-T-G-G-K-Q-Y-K-V-A-E-G-D-L-V-K-V-E-K-I-E-G-E-P-G-A-S-V-A-L-T-P-V-L-L-V-D-G-A-D-V-T-T-A-A-D-K-L-A-S-V-S-V-N-T-E-I-V-E-H-T-K-G-P-K-I-K-I-L-K-Y-K-N-K-T-G-Y-K-K-R-Q-G-H-R-Q-K-L-T-V-L-K-V-T-G-I-K


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-I-K-R-N-K-T-N-E-K-A-R-L-R-N-Q-A-I-R-S-A-V-R-T-E-I-R-K-F-H-A-A-I-D-G-G-D-K-A-A-A-E-S-Q-L-R-V-A-S-R-A-L-D-K-A-V-T-K-G-V-F-H-R-N-N-A-A-N-K-K-S-S-L-A-R-A-F-N-K-L-G


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-I-E-V-F-N-E-S-G-Y-D-G-V-N-E-E-M-L-I-D-V-L-S-F-A-L-G-E-M-D-I-H-P-D-A-E-A-S-I-H-I-V-D-S-D-T-I-A-E-L-H-V-K-W-L-D-L-E-G-P-T-D-V-M-S-F-P-M-D-E-L-T-P-G-Y-S-R-P-D-G-G-A-P-G-P-A-M-L-G-D-I-V-L-C-P-E-F-A-E-K-Q-A-T-K-A-G-H-D-L-S-H-E-L-A-L-L-T-V-H-G-C-L-H-L-L-G-Y-D-H-V-E-P-A-Q-E-R-E-M-F-A-L-Q-N-E-L-L-A-D-W-Y-D-D-V-D-R-R-G-V-V-Y-Q-P-K-P-T-G-P-G-A-F-P-T-A-A-D-R-L-E-L-D-Q-T-M-I-A-E-E-Q-G-E-P-G-E-S-G-A-S-A-R


### FUNCTION Part of cytochrome c oxidase, its function is unknown ### SEQUENCE -M-K-S-S-S-K-I-M-Y-G-L-T-V-F-L-A-A-M-A-V-I-Y-I-F-G-T-M-Y-V-D-D-R-G-S-V-M-G-L-E-W-V-G-A-T-A-L-V-L-S-T-A-L-T-L-M-L-G-V-Y-I-H-I-T-E-R-R-T-D-V-L-P-E-D-W-E-E-A-E-V-A-D-K-A-G-T-L-G-F-F-S-P-G-S-I-W-P-A-A-M-S-G-A-V-G-L-L-G-F-G-I-I-F-M-H-Y-W-L-I-L-V-G-A-L-A-L-T-Y-T-I-A-K-L-N-F-Q-Y-G-V-P-R-E-K-H


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-T-E-L-Q-I-G-R-V-I-K-S-H-G-I-R-G-E-V-V-V-E-V-T-T-D-D-P-D-I-R-Y-A-P-G-E-V-L-H-G-R-Q-T-G-R-E-H-T-L-T-I-D-T-A-R-A-H-Q-G-R-L-L-I-K-F-E-E-I-P-D-R-T-A-A-D-S-L-R-G-T-R-F-F-A-P-P-L-E-R-E-D-D-E-E-G-F-Y-D-H-E-L-E-G-L-R-I-I-H-D-G-A-D-I-G-V-V-T-G-V-M-H-G-P-A-G-E-I-L-E-V-E-L-T-S-G-K-E-V-L-I-P-F-V-H-A-I-V-P-E-V-D-L-E-A-G-T-A-T-I-T-P-P-D-G-L-L-D-L


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-I-L-D-K-V-D-S-A-Y-L-R-D-D-V-P-A-F-R-P-G-D-T-L-D-V-H-V-K-V-I-E-G-T-N-T-R-T-Q-L-F-K-G-V-V-I-R-R-Q-G-S-G-I-R-E-T-F-T-V-R-K-V-S-F-G-I-G-V-E-R-T-F-P-V-H-S-P-N-L-E-K-I-E-V-V-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-E-L-R-G-K-A-A-R-I-K-E-K-R


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-D-E-I-L-F-D-S-E-E-R-M-S-N-T-V-E-H-T-R-E-D-L-I-T-I-R-T-G-R-A-N-P-A-M-F-N-G-V-L-A-E-Y-Y-G-V-P-T-P-I-T-Q-M-S-S-I-S-V-P-E-P-R-M-L-I-I-K-P-Y-E-M-S-S-M-G-V-I-E-N-A-I-R-N-S-D-L-G-V-N-P-T-N-D-G-Q-V-L-R-V-T-I-P-Q-L-T-E-E-R-R-R-D-M-V-K-I-A-K-G-K-G-E-D-G-K-I-A-I-R-N-V-R-R-K-G-M-E-Q-L-K-K-L-Q-K-D-G-E-F-G-E-D-E-V-A-A-A-E-K-E-L-D-K-I-T-A-H-Y-V-E-Q-V-D-E-I-V-A-R-K-E-A-E-L-M-E-V


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-F-P-T-A-E-E-L-T-A-L-I-A-P-V-V-A-T-R-H-L-D-V-E-G-L-R-V-T-K-A-G-P-K-S-T-V-A-I-K-L-D-S-D-S-R-P-D-L-D-L-L-E-V-V-S-Q-E-I-G-E-L-F-D-A-A-E-A-R-G-E-L-S-F-G-A-G-Y-L-L-E-V-S-T-P-G-V-D-M-P-L-T-Q-P-R-H-W-R-R-N-R-T-R-L-V-S-L-D-V-D-G-K-K-R-I-A-R-I-G-A-L-N-A-E-E-T-A-V-I-L-I-E-R-N-K-K-A-L-S-V-T-V-L-E-L-A-N-S-P-R-A-V-V-E-I-E-F-A-K-P-A-Q-D-E-L-D-L-A-G-R-T-F-D-E-A-V-E-E-T-D-H


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-V-D-N-A-R-A-A-R-M-A-K-R-I-Q-T-I-V-A-S-A-I-E-R-E-I-K-D-R-R-L-E-Y-I-T-I-T-D-V-T-M-T-G-D-L-H-D-A-T-V-F-Y-T-V-R-G-E-N-V-G-D-E-P-D-L-E-A-A-A-E-A-L-H-R-A-R-G-Q-L-R-K-I-V-G-E-Q-L-G-V-R-F-T-P-T-L-T-Y-R-V-D-T-V-P-E-A-S-A-H-M-E-A-L-L-E-R-A-R-Q-R-D-A-E-L-A-K-L-K-E-N-A-V-P-A-G-D-P-N-P-Y-K-S-D-T-R-E-E-D-E-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-S-E-Q-K-K-S-I-L-A-E-Y-G-L-H-E-T-D-T-G-S-P-E-A-Q-I-A-M-L-T-N-R-I-N-T-L-T-E-H-L-K-F-H-K-H-D-H-H-S-R-R-G-L-L-L-L-V-G-R-R-R-G-L-L-K-Y-L-A-D-N-N-V-D-R-Y-R-D-L-I-A-R-L-G-L-R-R


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Y-C-P-F-C-Q-H-G-H-S-R-V-I-D-S-R-V-I-E-A-G-S-A-I-R-R-R-R-E-C-S-Q-C-Q-G-R-F-T-T-I-E-K-A-V-L-L-V-L-K-R-N-G-V-T-E-P-F-S-R-E-K-V-V-T-G-V-R-R-A-C-Q-G-R-D-V-S-D-D-S-L-K-R-L-A-Q-Q-V-E-E-T-V-R-S-S-G-S-S-Q-V-R-A-N-D-I-G-L-A-I-L-D-P-L-R-E-L-D-E-V-A-Y-L-R-F-A-S-V-Y-K-S-F-E-S-A-D-D-F-E-K-E-I-R-L-M-R-R-Q-S-R-E-K-Q-V-Q-Q-G


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-I-L-S-H-R-W-Q-C-T-I-V-P-V-D-S-G-R-Q-R-R-A-Y-P-E-G-V-T-E-N-L-N-T-I-D-S-I-R-L-L-R-L-D-P-G-L-P-M-P-R-R-A-H-R-G-D-A-G-V-D-L-H-S-T-T-D-V-V-I-A-P-G-H-R-E-L-V-G-T-G-V-A-I-A-L-P-L-G-T-V-G-L-I-H-P-R-S-G-L-A-A-R-E-G-L-S-I-V-N-A-P-G-T-V-D-A-D-Y-R-G-E-I-K-V-C-L-I-N-L-D-P-S-T-P-I-T-I-T-R-G-D-R-I-A-Q-L-I-I-Q-R-V-E-L-V-D-F-V-E-V-D-E-L-D-E-T-T-R-G-D-Q-G-H-G-S-T-G-R-G-S-T-A


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-K-F-I-K-H-T-G-V-G-V-P-L-Q-R-S-N-V-D-T-D-Q-I-I-P-A-V-Y-L-K-R-V-T-R-T-G-F-E-D-G-L-F-S-N-W-R-K-N-D-P-D-F-V-L-N-Q-D-T-Y-K-N-G-S-V-L-I-A-G-P-D-F-G-T-G-S-S-R-E-H-A-V-W-A-L-M-D-Y-G-F-R-A-V-F-S-S-R-F-A-D-I-F-R-G-N-S-G-K-A-G-L-L-T-G-I-M-E-Q-S-D-I-E-L-L-W-K-L-M-E-Q-T-P-G-L-E-M-T-V-D-L-E-N-Q-T-V-V-A-G-D-T-V-I-S-F-E-V-D-P-Y-I-R-W-R-L-M-E-G-L-D-D-V-G-L-T-L-R-K-V-D-E-I-E-A-Y-E-A-K-R-P-A-F-K-P-S-A-L


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-P-E-I-S-R-D-Q-V-A-H-L-A-K-L-A-R-L-A-L-S-E-E-E-L-Q-Q-F-A-G-Q-I-D-D-I-V-G-H-V-S-A-V-Q-N-V-D-A-E-G-V-E-P-M-S-H-P-H-S-I-M-T-T-M-R-D-D-V-V-V-K-T-L-T-P-E-Q-A-L-D-Q-A-P-A-V-E-D-G-R-F-M-V-P-Q-I-L-G-E-G-D


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-E-I-T-V-E-L-V-S-V-E-R-M-L-W-S-G-Q-A-S-I-V-T-A-Q-T-T-E-G-E-I-G-V-L-P-D-H-E-P-M-L-G-Q-L-V-E-N-G-V-V-T-I-Q-P-T-D-G-D-R-L-V-A-G-V-Q-G-G-F-L-S-V-S-K-E-K-V-T-I-L-A-D-F-A-V-W-A-H-E-V-D-S-A-S-A-E-A-D-L-N-S-D-D-E-L-A-K-A-R-A-E-A-G-L-R-A-V-R-R-S-S-E-G-L


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-N-P-I-Y-I-L-A-H-A-N-A-E-Y-L-P-L-E-S-G-N-S-I-L-L-P-K-A-Y-D-I-V-W-S-L-I-P-F-L-I-I-L-F-V-F-W-K-F-V-L-P-K-F-Q-E-V-L-T-E-R-E-D-R-I-K-G-G-I-Q-R-A-E-A-A-Q-A-E-A-K-A-A-L-E-K-Y-N-A-Q-L-A-E-A-R-T-E-A-A-E-I-R-E-Q-A-R-E-R-G-K-Q-I-E-V-E-M-K-A-K-A-E-E-E-S-N-R-I-I-E-A-G-T-K-Q-L-M-A-Q-R-E-Q-V-V-N-E-L-R-R-E-M-G-Q-N-S-I-N-L-A-E-H-L-L-G-D-Q-L-S-D-D-V-K-R-S-G-T-I-D-R-F-L-A-D-L-D-T-V-A-P-N-G-K


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-S-N-V-G-W-G-E-I-L-L-L-F-I-V-G-L-I-V-I-G-P-E-R-L-P-R-L-M-E-D-L-K-A-A-I-V-A-A-R-T-A-I-N-N-A-K-Q-N-L-D-T-D-F-G-E-E-F-D-E-I-R-K-P-M-A-Q-I-A-Q-I-R-S-M-S-P-K-T-A-I-T-R-A-L-F-D-G-D-D-S-F-L-D-S-F-D-P-K-K-I-M-A-D-D-T-A-G-Q-A-H-R-Q-Q-V-A-K-T-G-T-T-P-E-H-A-E-V-V-E-R-P-A-D-R-I-D-P-T-Q-S-P-N-T-P-G-K-N-N-D-G-G-K-P-P-A-G-G-G-Y-T-W-T-D-L-I


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-N-D-S-P-V-L-V-V-G-L-G-N-P-G-P-K-Y-V-G-T-R-H-N-I-G-F-E-V-V-E-E-L-V-G-R-N-Y-A-N-F-S-V-H-K-R-S-N-T-E-I-A-Q-L-P-G-L-I-V-A-K-P-R-S-F-M-N-L-S-G-T-P-I-R-A-L-C-D-F-F-K-I-S-P-A-N-V-L-V-V-H-D-E-L-D-L-D-F-G-Q-V-K-L-R-Q-G-G-G-D-H-G-H-N-G-L-K-S-T-S-R-S-L-G-T-K-D-Y-W-K-L-S-V-G-I-G-R-P-P-G-R-M-D-P-A-T-F-V-L-K-P-F-S-K-Q-E-Q-D-S-V-P-I-M-A-A-D-A-A-D-L-I-E-E-H-I-R-T-L


### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-I-T-E-I-I-G-N-I-H-E-Q-P-E-L-R-T-H-H-A-E-T-I-T-L-V-D-D-A-L-T-K-R-I-Q-R-L-V-S-D-H-G-S-E-L-G-L-R-L-P-S-G-H-P-P-L-R-D-G-D-V-L-H-S-D-G-E-N-S-I-L-I-A-V-A-P-T-D-V-L-M-I-R-P-G-T-L-R-D-M-A-F-V-A-H-S-L-G-N-R-H-L-P-A-Q-F-D-G-D-V-M-I-V-R-Y-D-N-T-V-V-D-F-L-E-H-Y-G-V-R-Y-E-R-R-S-T-V-M-P-T-P-F-R-H-S-E-H-T-H


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-N-E-Q-R-K-A-I-V-A-R-Y-A-E-R-R-A-E-L-K-A-I-I-R-N-P-N-T-S-D-E-D-R-L-D-A-Q-F-E-L-N-R-Q-P-R-D-A-A-Q-V-R-V-R-N-R-D-A-H-D-G-R-P-R-G-Y-L-R-K-F-G-L-S-R-V-R-M-R-E-M-A-H-R-G-E-L-P-G-V-R-K-S-S-W


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-K-K-K-V-D-E-N-N-Q-V-L-A-T-N-R-K-A-R-H-D-Y-Q-I-L-D-T-W-E-A-G-V-V-L-L-G-T-E-I-K-S-L-R-E-G-K-A-S-L-V-D-A-F-A-V-I-D-N-G-E-V-W-L-H-N-L-H-I-P-T-Y-S-M-G-S-W-T-N-H-S-P-K-R-T-R-K-L-L-L-H-R-R-E-I-D-S-L-M-G-K-V-R-D-G-N-R-T-L-V-P-L-K-L-Y-L-V-N-G-R-V-K-L-E-L-G-L-A-Q-G-K-Q-D-Y-D-K-R-Q-D-I-K-R-R-T-E-E-R-E-V-T-R-E-L-G-R-R-I-K-G-I-N-A


### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-Q-I-V-L-A-S-Q-S-P-S-R-L-M-I-L-R-Q-A-G-V-E-P-V-I-H-P-A-H-V-D-E-D-A-I-I-A-Q-L-A-G-A-E-P-D-E-I-V-T-R-L-A-L-A-K-A-Q-A-I-A-P-E-H-P-G-D-V-V-I-G-G-D-S-M-L-L-L-D-G-Q-L-Q-G-K-P-H-T-P-E-A-T-I-E-R-W-R-Q-Q-R-G-R-T-A-H-L-I-T-G-H-A-I-C-L-G-E-R-R-V-V-E-A-S-R-T-T-I-H-F-A-D-A-S-D-T-D-I-E-A-Y-A-R-S-G-E-P-L-Q-C-A-G-A-F-T-L-E-A-L-G-G-W-F-I-D-A-I-E-G-D-P-S-S-V-I-G-L-S-L-P-V-V-R-R-A-L-Y-S-F-G-L-N-A-S-D-F-W-T-K


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-S-T-Y-H-P-K-S-G-D-I-T-R-K-W-Y-V-I-D-A-T-D-V-V-L-G-R-L-A-T-H-A-A-D-L-L-R-G-K-G-K-P-L-F-A-P-N-V-D-C-G-D-H-V-I-I-I-N-A-D-K-V-A-I-T-S-N-K-R-D-R-E-M-R-Y-R-H-S-G-Y-P-G-G-L-K-S-M-T-L-G-R-S-L-E-L-H-P-E-R-V-L-E-E-S-I-T-G-M-M-P-H-N-K-L-T-A-A-S-V-K-K-L-H-V-F-A-G-S-E-H-P-Y-A-A-Q-K-P-E-T-Y-E-I-K-K-V-A-Q


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-G-A-I-E-V-E-G-R-V-V-E-P-L-P-N-A-M-F-R-V-E-L-D-N-G-H-K-V-L-A-H-I-S-G-K-M-R-Q-H-Y-I-R-I-L-P-E-D-R-V-V-V-E-L-S-P-Y-D-L-T-R-G-R-I-V-Y-R-Y-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-N-T-E-N-K-Q-K-R-V-S-V-G-K-D-I-A-T-R-R-R-V-A-R-A-R-R-H-F-R-I-R-K-T-L-R-G-T-P-E-A-P-R-L-V-V-H-R-S-S-R-H-M-H-V-Q-I-I-D-D-L-A-G-H-T-L-A-A-A-S-S-I-E-P-E-V-R-A-V-E-G-D-K-K-A-K-G-A-K-V-G-Q-L-I-A-E-R-A-K-A-A-G-I-E-Q-V-V-F-D-R-A-G-Y-K-Y-H-G-R-V-A-A-L-A-D-A-A-R-E-G-G-L-K-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-N-P-I-A-I-P-S-G-V-E-V-K-I-D-G-R-L-V-D-V-K-G-P-K-G-N-L-N-V-T-L-P-E-P-I-T-A-S-I-E-N-N-E-I-L-V-T-R-P-D-D-H-R-N-S-R-S-M-H-G-L-S-R-S-L-V-N-N-L-V-V-G-V-T-E-G-Y-T-I-K-M-E-I-F-G-V-G-Y-R-V-A-L-K-G-K-N-L-E-F-S-L-G-Y-S-H-P-V-L-I-E-A-P-E-G-I-T-F-A-V-D-G-T-T-K-L-S-I-S-G-I-D-K-Q-K-V-G-Q-V-A-A-V-I-R-R-L-R-K-D-D-P-Y-K-G-K-G-I-R-Y-E-G-E-Q-I-R-R-K-V-G-K-T-G-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-I-A-D-M-L-S-R-V-R-N-A-N-N-A-H-H-D-T-V-S-M-P-S-S-K-L-K-A-N-I-A-E-I-L-K-Q-E-G-Y-I-E-S-Y-T-V-E-D-A-K-V-G-K-T-L-T-L-E-L-K-Y-T-G-N-R-V-R-S-I-A-G-L-R-R-V-S-K-P-G-L-R-V-Y-A-K-S-T-N-L-P-Q-V-L-G-G-L-G-V-A-I-I-S-T-S-Q-G-L-L-T-D-R-Q-A-T-E-K-G-V-G-G-E-V-L-A-Y-V-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-E-N-Y-T-P-R-L-K-S-R-Y-Q-D-E-I-R-P-N-L-Q-T-Q-F-E-F-S-N-V-M-Q-I-P-G-V-T-K-V-V-V-N-M-G-V-G-D-A-A-R-D-S-K-M-I-N-G-A-L-E-D-L-T-A-I-T-G-Q-K-P-Q-L-R-R-A-K-K-S-I-A-N-F-K-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-D-R-M-W-E-F-L-D-R-L-L-T-V-A-L-P-R-I-R-D-F-R-G-L-S-D-Q-Q-F-D-G-H-G-N-Y-T-F-G-L-T-E-Q-T-M-F-Y-E-I-D-V-D-K-I-D-R-P-R-G-M-D-I-T-V-V-T-T-A-V-T-D-D-E-G-R-A-L-L-R-E-L-G-F-P-F-K-G-E-D-G-K-K-Q


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-V-H-K-G-D-M-V-L-V-I-S-G-P-D-K-G-A-K-G-K-V-I-A-A-F-P-K-T-E-K-V-L-V-E-G-V-N-R-I-K-K-H-V-A-N-S-A-P-E-R-G-A-E-S-G-G-I-V-T-Q-E-A-P-I-H-V-S-N-V-M-V-I-D-A-D-G-N-P-T-R-V-G-F-R-V-D-E-N-G-K-K-V-R-V-S-R-R-S-G-K-D-I


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-I-A-D-N-T-G-A-R-E-I-L-C-I-R-V-L-G-G-S-T-R-R-F-A-G-I-G-D-V-I-V-A-T-V-K-E-A-A-P-G-G-N-V-K-S-G-E-I-V-K-A-V-I-V-R-T-K-K-E-T-R-R-A-D-G-S-Y-I-S-F-D-E-N-A-A-V-I-I-K-N-D-N-E-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-K-K-F-M-K-I-V-S-L-A-P-E-V-I


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-A-N-V-S-N-K-E-K-G-A-R-K-V-R-T-G-Y-V-V-S-D-K-M-Q-K-T-I-V-V-E-L-E-D-R-K-Q-H-A-L-Y-S-K-I-L-R-T-N-K-K-V-K-A-H-D-E-E-N-I-A-G-I-G-D-L-V-R-I-E-E-T-R-P-L-S-K-D-K-N-Y-R-L-I-E-I-I-E-K-A-K


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-I-P-K-R-V-K-Y-R-R-Q-H-R-P-T-R-S-G-I-S-K-G-G-N-R-V-T-F-G-E-Y-G-I-Q-A-L-E-P-A-Y-I-T-N-R-Q-I-E-S-A-R-I-A-I-N-R-H-V-K-R-G-G-K-V-W-I-N-I-F-P-D-R-P-L-T-Q-K-P-L-G-V-R-M-G-S-G-K-G-P-V-E-K-W-V-A-N-V-K-P-G-R-I-L-F-E-M-S-Y-P-D-E-A-M-A-L-E-A-L-R-R-A-G-Q-K-L-P-C-K-V-R-I-V-K-R-E-D-Q-L


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-D-N-I-T-S-A-R-A-T-A-R-F-V-R-V-S-P-M-K-A-R-R-V-I-D-L-V-R-G-K-T-V-V-E-A-L-S-I-L-K-Y-A-P-Q-A-A-S-E-P-V-A-K-V-V-A-S-A-A-A-N-A-E-N-N-F-G-L-D-P-R-T-L-V-I-S-E-A-Y-A-D-E-G-P-T-M-R-R-F-Q-P-R-A-Q-G-R-A-F-Q-I-R-K-R-S-S-H-I-T-V-V-V-E-S-Q-K-E-G-A-N


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-A-T-I-A-N-P-R-D-I-I-L-A-P-V-V-S-E-K-S-Y-G-L-M-E-Q-N-V-Y-T-F-F-V-A-R-D-A-N-K-T-Q-I-K-I-A-V-E-E-I-F-G-V-K-V-A-S-V-N-T-V-N-R-E-G-K-R-K-R-S-R-S-G-F-G-V-R-K-A-T-K-R-A-Y-V-T-L-R-E-G-S-D-S-I-D-I-F-N-G-S-V-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-S-A-A-P-K-R-P-V-V-K-D-P-V-Y-D-S-E-L-V-T-Q-L-V-N-K-I-L-L-D-G-K-K-S-T-A-E-R-I-V-Y-G-A-L-E-I-C-R-E-K-T-G-L-E-P-V-G-T-L-E-K-A-L-G-N-V-R-P-D-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-P-A-R-A-T-T-L-A-L-R-W-L-V-T-F-T-R-Q-R-R-E-N-T-M-V-E-R-L-A-N-E-I-M-D-A-A-N-G-L-G-A-S-V-K-R-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-Y-R-W


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-L-T-K-D-E-L-I-E-A-F-K-E-M-T-L-I-E-L-S-E-F-V-K-E-F-E-E-V-F-E-V-T-A-A-A-P-V-A-V-A-A-A-G-A-A-G-G-E-A-A-A-A-E-E-K-D-E-F-D-V-V-L-E-D-A-G-A-K-K-I-G-V-I-K-V-V-R-E-L-V-S-G-L-G-L-K-E-A-K-E-L-V-E-G-A-P-K-A-I-L-E-G-A-N-K-D-D-A-E-A-A-K-A-K-L-E-E-A-G-A-K-V-T-L-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-N-P-K-N-E-A-A-L-A-E-L-K-A-Q-F-A-E-T-D-S-I-V-L-T-E-Y-R-G-L-T-V-A-Q-T-T-E-L-R-R-A-L-G-D-D-V-Q-Y-S-V-A-K-N-T-L-V-K-I-A-A-Q-E-A-G-V-E-G-L-D-D-L-L-T-G-P-T-A-V-A-F-I-K-G-E-A-V-D-T-A-K-V-L-K-K-F-G-D-D-N-K-A-F-V-V-K-G-G-Y-M-D-G-N-A-L-T-A-D-Q-V-K-A-I-A-E-L-D-N-R-E-T-T-L-A-K-L-A-G-A-M-K-G-N-L-A-K-A-A-G-L-F-N-A-P-A-S-Q-V-A-R-L-A-A-A-L-Q-E-K-K-D-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-P-K-K-K-K-V-T-G-L-I-K-L-Q-I-Q-A-G-Q-A-N-P-A-P-P-V-G-P-A-L-G-A-H-G-V-N-I-M-E-F-C-K-A-Y-N-A-A-T-E-N-Q-R-G-N-V-V-P-V-E-I-T-V-Y-E-D-R-S-F-D-F-K-L-K-T-P-P-A-A-K-L-L-L-K-A-A-G-L-Q-K-G-S-G-V-P-H-T-N-K-V-G-K-V-T-M-D-Q-I-R-E-I-A-E-T-K-K-E-D-L-N-A-R-D-I-D-A-A-A-K-I-I-A-G-T-A-R-S-M-G-I-T-V-E-G


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-L-P-A-Q-N-K-L-T-S-S-V-Q-F-R-T-T-M-R-K-G-R-R-A-G-S-S-T-V-V-V-H-L-W-D-S-A-E-S-L-D-G-T-G-E-K-G-E-V-A-S-F-G-G-P-R-F-G-L-I-V-S-K-A-V-G-N-A-V-I-R-H-R-T-S-R-R-L-R-H-V-C-A-R-I-A-A-D-S-P-E-L-L-T-P-T-H-H-V-V-I-R-A-L-A-G-S-G-Q-A-S-S-Q-D-L-E-R-D-I-R-H-G-L-R-K-A-G-R-V-R-T-D-K


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-K-V-T-P-D-T-P-G-R-D-D-P-G-P-G-R-R-I-G-L-D-V-G-T-V-R-I-G-V-A-A-S-D-R-D-A-R-L-A-M-P-V-E-T-V-P-R-E-T-G-M-K-G-P-D-R-G-D-I-D-R-L-I-D-I-I-T-E-Y-D-A-V-E-V-V-V-G-L-P-R-D-L-Q-G-N-G-S-A-S-V-K-Q-A-R-E-I-A-F-R-I-R-R-R-L-T-A-T-G-R-E-I-P-V-R-L-G-D-E-R-L-T-T-V-V-A-T-Q-A-L-R-A-S-G-I-N-E-R-D-G-R-K-V-I-D-Q-A-A-A-V-E-I-L-Q-T-W-L-D-G-R-A-T-A-L-N-T-L-P-E-T-P-H-T-D-E-K-G-N-F-P-R


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-T-A-D-F-K-N-G-L-V-L-K-V-D-G-K-L-Q-Q-I-V-E-F-Q-H-V-K-P-G-K-G-P-A-F-V-R-T-K-L-K-D-V-V-T-G-K-T-V-D-K-T-W-N-A-G-V-K-V-E-T-A-T-V-D-R-R-D-M-T-Y-L-Y-N-D-G-S-S-Y-I-L-M-D-D-K-T-F-E-Q-F-E-L-P-L-D-A-F-G-D-A-G-R-F-L-L-E-N-M-R-V-Q-V-S-F-H-D-G-E-A-L-F-G-E-L-P-V-S-V-D-L-R-V-E-H-T-D-P-G-L-Q-G-D-R-S-T-G-G-T-K-P-A-T-L-E-T-G-A-E-I-Q-V-P-L-F-I-E-T-G-N-V-L-K-V-D-T-R-D-G-S-Y-L-S-R-V-N-N


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-S-E-S-R-Q-G-Y-K-R-H-G-A-R-Y-K-A-R-R-R-A-V-D-I-L-F-E-A-E-S-R-D-V-D-P-V-A-I-I-D-D-R-K-T-L-S-N-A-V-D-P-V-V-A-P-V-A-E-Y-T-E-A-I-I-N-G-V-A-V-E-L-D-T-I-D-D-L-L-S-E-H-I-A-D-T-W-L-L-E-R-L-P-S-V-D-R-A-V-L-R-V-A-C-W-E-M-L-Y-N-P-D-V-P-V-T-T-A-V-V-E-A-V-E-I-A-S-Q-Y-S-T-D-K-A-G-A-Y-I-N-A-T-L-D-N-M-A-S-K-V-D-E-L-R-E-R-A-A-N-P-G-A-V-S-G-S-D-A-P-V-A-P-W-D-D-S-E-E-L-P-A-E-D-E-A-E-D-S-R-P


### FUNCTION Regulates the transcription of the pyrimidine nucleotide  operon in response to exogenous pyrimidines ### SEQUENCE -M-S-E-R-R-N-T-V-V-E-L-L-G-E-N-D-V-S-R-T-V-A-R-I-A-H-Q-I-I-E-K-T-A-L-D-S-E-G-A-D-R-V-M-L-L-G-I-P-S-G-G-V-P-L-A-E-R-L-A-A-K-I-E-E-F-S-G-V-R-V-D-T-G-A-I-D-I-T-L-Y-R-D-D-L-R-N-K-P-H-R-A-L-Q-P-T-S-I-P-S-G-G-I-D-K-T-T-V-V-L-V-D-D-V-L-F-S-G-R-T-V-R-A-A-L-D-A-L-R-D-L-G-R-P-N-Y-I-Q-L-A-V-L-V-D-R-G-H-R-Q-L-P-I-R-A-D-Y-V-G-K-N-L-P-T-A-R-A-E-D-V-T-V-M-L-R-E-I-D-G-R-D-A-V-T-L-T-R-E-E-G-E-G-D-N


### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-S-G-D-K-P-H-G-R-L-V-I-L-A-G-P-S-A-V-G-K-S-T-V-V-D-R-L-R-S-D-V-P-N-L-Y-F-S-V-S-M-T-T-R-D-P-R-P-G-E-V-D-G-R-D-Y-F-Y-V-T-A-Q-E-F-Q-E-K-I-D-R-G-E-M-L-E-W-A-D-I-H-G-G-L-Q-R-S-G-T-P-A-E-P-V-R-Q-A-R-E-E-G-R-P-V-L-V-E-V-D-L-V-G-A-R-N-I-A-R-L-I-P-E-A-E-T-I-F-L-A-P-P-S-W-E-V-L-V-E-R-L-T-G-R-G-T-E-S-Q-D-V-I-N-R-R-L-E-T-A-R-E-E-L-A-A-Q-S-E-F-K-H-V-I-I-N-D-D-V-D-T-A-V-S-A-I-K-A-V-L-L-G-T


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-S-V-T-N-V-S-N-E-T-N-A-T-K-A-V-F-D-P-P-M-G-I-T-A-P-P-I-D-E-L-L-D-K-V-T-S-K-Y-A-L-V-I-F-A-A-K-R-A-R-Q-I-N-S-Y-Y-Q-Q-A-D-E-G-V-F-E-F-I-G-P-L-V-T-P-Q-P-G-E-K-P-L-S-I-A-L-R-E-I-N-V-G-L-L-D-H-E-E-G


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-T-V-R-D-V-R-I-F-G-D-P-V-L-T-S-R-A-D-E-V-V-D-F-D-E-S-L-A-T-L-I-D-D-M-F-D-T-M-E-D-A-G-G-V-G-L-A-A-N-Q-V-G-V-L-R-R-V-F-V-F-D-C-S-H-V-D-G-G-L-R-G-H-V-V-N-P-V-W-E-P-I-G-E-E-T-Q-T-G-K-E-G-C-L-S-I-P-D-V-S-A-E-T-T-R-Y-E-T-V-K-L-S-G-Q-D-R-D-G-N-P-I-G-L-V-A-S-G-L-L-S-R-C-I-Q-H-E-T-D-H-L-D-G-V-L-F-L-K-R-L-D-P-A-E-R-K-A-A-M-G-V-I-R-A-S-D-W-F-N-K


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-A-K-E-G-L-P-E-I-T-L-P-D-A-T-G-L-R-V-A-V-V-T-A-R-W-N-A-E-I-C-D-R-L-H-D-H-A-V-T-A-G-R-A-A-G-A-E-V-S-E-Y-R-V-V-G-A-L-E-L-P-V-V-V-Q-E-L-A-R-T-H-D-A-V-V-A-L-G-C-V-I-R-G-G-T-P-H-F-D-Y-V-C-D-S-V-T-E-G-L-T-R-I-A-L-D-T-S-T-P-I-G-N-G-V-L-T-T-N-T-E-E-Q-A-I-E-R-S-G-A-E-G-S-V-E-D-K-G-A-E-A-M-V-A-A-L-D-T-A-L-V-L-S-R-I-R-A-D-R-G


### FUNCTION AcnR negatively controls the expression of the aconitase gene acn ### SEQUENCE -M-S-V-A-T-G-D-K-P-V-N-S-R-Q-E-I-L-E-G-A-R-R-C-F-A-E-H-G-Y-E-G-A-T-V-R-R-L-E-E-A-T-G-K-S-R-G-A-I-F-H-H-F-G-D-K-E-K-L-F-L-A-L-A-R-E-D-A-A-R-M-A-E-T-V-S-E-N-G-L-V-E-V-M-R-G-M-L-E-D-P-E-R-Y-D-W-L-S-I-R-L-E-I-S-K-Q-L-R-T-D-P-E-F-R-A-K-W-T-D-H-Q-S-V-L-D-E-A-V-R-V-R-L-A-R-N-A-D-K-G-R-M-R-T-D-V-P-I-E-V-L-H-L-Y-L-E-T-V-M-D-G-F-I-S-R-L-A-T-G-A-S-T-E-G-L-S-E-V-L-D-L-V-E-T-S-V-R-R-P-D


### FUNCTION Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation The tagging system is termed pupylation ### SEQUENCE -M-S-D-R-Q-T-Q-I-P-A-G-G-G-R-E-D-D-H-D-D-Q-V-Q-S-A-G-Q-V-Q-V-N-T-E-G-V-D-D-L-L-D-E-I-D-G-L-L-E-N-N-A-E-E-F-V-R-S-Y-V-Q-K-G-G-E


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-S-L-G-P-W-E-I-A-I-I-V-L-L-I-I-V-L-F-G-A-K-K-L-P-D-A-A-R-S-I-G-R-S-M-R-I-F-K-S-E-V-K-E-M-Q-K-D-D-E-T-P-A-Q-P-E-Q-Q-P-Q-G-Y-Q-H-P-Q-Q-I-E-A-P-Q-N-L-Q-Q-P-N-F-Q-Q-H-Y-Q-N-Q-P-Q-Q-P-D-Y-R-Q-N-Y-E-D-P-N-R-T-P


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-P-L-V-H-V-M-L-L-S-C-G-V-A-A-D-A-F-A-C-S-I-A-R-G-T-A-I-R-V-N-I-I-K-R-S-L-I-L-A-G-I-F-G-V-F-Q-A-L-M-P-V-I-G-W-G-I-G-Y-F-F-A-E-L-S-F-I-R-A-I-D-H-W-V-A-F-L-L-L-A-G-V-G-A-K-M-I-W-D-A-F-H-Q-D-A-D-V-D-V-I-D-T-G-A-V-Q-L-R-P-A-L-I-L-G-L-A-T-S-I-D-A-L-A-V-G-M-G-M-A-F-V-H-A-P-I-I-T-L-A-L-A-M-G-L-T-T-F-V-L-S-L-V-G-A-W-M-G-H-H-G-G-G-R-F-G-G-W-A-T-V-I-G-G-L-V-L-I-G-L-G-G-N-I-L-F-D-H-M-L-G


### FUNCTION An essential component of the PknG signaling pathway When unphosphorylated, it inhibits the activity of 2-oxoglutarate dehydrogenase When phosphorylated it does not inhibit 2-oxoglutarate dehydrogenase ### SEQUENCE -M-S-D-N-T-G-T-P-E-P-Q-V-E-T-T-S-V-F-R-A-D-L-L-K-E-M-S-G-A-G-S-A-P-A-A-T-G-A-D-N-L-P-A-G-S-A-L-L-V-V-K-R-G-P-N-A-G-A-R-F-L-L-D-Q-P-T-T-T-A-G-R-H-P-E-S-D-I-F-L-D-D-V-T-V-S-R-R-H-A-E-F-R-I-N-E-G-E-F-E-V-V-D-V-G-S-L-N-G-T-Y-V-N-R-E-P-R-N-S-Q-V-L-Q-T-G-D-E-I-Q-I-G-K-F-R-L-V-F-L-A-G-P-A-A


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-T-M-D-D-G-R-A-S-T-S-T-P-V-T-R-T-A-R-Q-A-L-I-V-Q-I-L-N-R-Q-R-V-T-S-Q-V-Q-L-S-E-L-L-L-D-E-G-I-D-I-T-Q-A-T-L-S-R-D-L-D-E-L-G-A-R-K-V-R-P-D-R-G-R-A-F-Y-A-I-G-P-V-D-T-T-I-G-E-D-L-R-G-P-Q-E-K-L-R-R-M-L-D-E-L-L-V-S-T-D-H-S-G-N-I-A-M-L-R-T-P-P-G-A-A-Q-Y-L-A-S-F-I-D-R-V-G-L-K-E-V-V-G-T-I-A-G-D-D-T-V-F-V-L-A-R-E-P-L-T-G-R-D-L-G-E-L-L-G-G-R-A-G-A-R-G-P-E-G-K-V


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-S-V-N-A-K-K-K-R-R-E-I-L-K-S-A-K-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-W-L-H-S-M-T-Y-A-Y-R-D-R-R-A-R-K-G-E-F-R-K-L-W-I-Q-R-I-N-A-A-A-R-M-N-G-I-T-Y-N-R-L-I-Q-G-L-R-L-A-E-I-E-V-D-R-K-I-L-A-D-L-A-V-N-D-F-A-A-F-S-A-I-C-E-A-A-K-A-A-L-P-E-D-V-N-A-P-K-A-A-A


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-T-Q-P-D-M-S-Q-I-L-A-Q-A-Q-Q-M-Q-A-Q-L-Q-A-A-Q-Q-E-I-L-A-S-S-V-V-G-D-A-A-N-G-L-V-T-V-T-M-S-G-S-G-E-V-T-A-V-N-I-D-P-K-V-V-D-P-E-D-V-E-T-L-Q-D-L-V-Q-G-A-F-L-D-A-H-K-K-V-A-D-L-A-Q-E-K-M-G-P-L-S-Q-G-F-G-G-D-M-G-S-L-F


### FUNCTION Involved in cell division ### SEQUENCE -M-P-K-A-K-V-T-K-N-S-I-A-P-V-S-S-N-P-S-A-N-R-T-P-V-K-I-N-S-T-G-T-P-M-W-Y-K-V-I-M-F-A-F-M-L-V-G-L-L-W-L-V-A-N-Y-L-V-G-P-Q-I-P-F-M-N-E-L-D-A-W-N-Y-G-I-G-F-G-L-L-I-I-G-L-L-M-T-M-G-W-R


### FUNCTION Has a post-transcriptional repressor function in flagellum biogenesis Associates with the 5'-UTR of fljK mRNA and promotes its degradation ### SEQUENCE -M-A-A-N-S-K-T-A-I-R-L-S-L-R-A-G-E-R-I-F-I-N-G-A-V-L-R-A-D-R-K-V-S-L-E-L-L-N-D-A-T-F-L-L-E-N-H-V-L-Q-P-E-D-T-T-T-P-L-R-Q-L-Y-F-A-A-Q-M-M-L-I-E-P-A-M-R-E-Q-A-G-A-T-F-A-Q-M-L-K-G-M-F-A-T-F-K-D-A-E-I-L-N-A-L-K-L-V-D-E-L-V-H-N-G-R-V-F-E-A-L-K-T-I-R-A-Q-Y-P-R-E-A-E-L-M-G-A-Q-P-V-V-W-P-V-T-K-S-G-K-S-A-G-A-N-P


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-S-K-K-Q-I-L-R-L-R-K-R-A-E-F-L-T-V-R-N-G-E-K-R-R-G-P-L-F-L-M-E-V-R-E-R-T-E-E-E-S-N-A-A-K-T-G-D-N-P-R-V-G-F-T-V-T-K-K-N-G-N-A-V-I-R-N-R-I-R-R-R-L-K-E-A-I-R-C-H-A-G-R-D-M-A-P-S-T-D-Y-V-I-V-A-R-E-Q-A-L-N-A-P-F-S-Q-L-T-E-E-L-S-R-R-I-T-A-K-G-E-R-R-S-G-R-K-R-R-T-E-R-P-E-P-G-P-V-N-G-K


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-R-N-W-R-Q-A-E-N-I-R-L-Y-I-A-V-G-C-G-A-A-I-G-A-L-L-R-F-L-S-G-W-V-I-V-A-I-L-G-A-N-P-L-W-G-T-S-F-V-N-I-V-G-S-F-I-I-M-F-F-A-T-L-T-G-P-E-G-R-W-L-V-S-P-A-W-R-Q-F-V-M-G-G-L-C-G-G-L-T-T-F-S-S-M-S-L-D-T-F-L-L-V-L-H-G-N-A-A-F-A-L-A-Y-L-C-G-L-V-F-L-S-L-S-A-A-M-L-G-L-I-A-A-Q-R-I-N-R


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-S-V-E-A-S-I-L-V-L-V-G-G-F-I-G-G-V-M-R-F-F-L-S-G-Y-V-G-R-R-I-G-E-T-F-P-W-G-T-F-V-V-N-V-S-G-A-F-V-I-G-T-A-A-G-L-G-A-R-L-G-A-I-F-S-T-T-I-F-H-E-F-I-M-V-G-L-L-G-G-Y-T-T-V-S-S-F-C-L-Q-S-V-N-L-M-L-D-G-E-Q-R-Q-A-L-F-N-I-V-A-S-A-L-L-C-V-L-A-V-A-A-G-Y-G-G-I-M-W-I-M-E-W-P-G


### FUNCTION Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose Essential for virulence May be involved in LPS biosynthesis or polysaccharide transport ### SEQUENCE -M-N-S-F-R-K-T-C-A-G-A-L-A-L-I-F-G-A-T-S-I-V-P-T-V-A-A-P-M-N-M-D-R-P-A-I-N-Q-N-V-I-Q-A-R-A-H-Y-R-P-Q-N-Y-N-R-G-H-R-P-G-Y-W-H-G-H-R-G-Y-R-H-Y-R-H-G-Y-R-R-H-N-D-G-W-W-Y-P-L-A-A-F-G-A-G-A-I-I-G-G-A-I-S-Q-P-R-P-V-Y-R-A-P-A-G-S-P-H-V-Q-W-C-Y-S-R-Y-K-S-Y-R-A-S-D-N-T-F-Q-P-Y-N-G-P-R-K-Q-C-R-S-P-Y-S-R


### FUNCTION Antioxidant protein with alkyl hydroperoxidase activity Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity ### SEQUENCE -M-S-I-D-D-L-K-S-K-I-P-D-F-A-K-D-V-R-L-N-L-S-S-M-A-S-N-E-T-L-T-P-Q-Q-K-Y-G-L-F-V-A-C-G-I-A-S-R-N-A-D-V-R-K-A-L-V-A-E-A-A-G-K-V-D-A-S-V-I-Q-A-A-K-A-A-A-S-I-M-G-M-N-N-V-Y-Y-R-F-V-H-L-A-S-N-K-D-Y-R-T-M-P-A-R-L-R-M-N-V-I-S-N-P-G-V-D-K-V-D-F-E-L-W-S-L-A-V-S-A-I-N-G-C-G-M-C-I-D-A-H-E-D-V-L-R-K-A-N-V-T-A-E-A-I-Q-A-A-V-R-F-A-S-I-I-Q-S-A-A-I-A-L-E-A-A-D-T-E


### FUNCTION Essential protein that is involved in the control of cell division, probably through the regulation of ctrA Its phosphorylation status is regulated by PdhS ### SEQUENCE -M-T-K-S-V-M-I-V-E-D-N-E-L-N-M-K-L-F-R-D-L-I-E-A-S-G-Y-E-T-I-R-T-R-S-G-L-E-A-L-D-L-A-R-E-H-H-P-D-L-I-L-M-D-I-Q-L-P-E-V-S-G-L-E-V-T-K-W-L-K-D-D-E-E-L-R-H-I-P-V-I-A-V-T-A-F-A-M-K-G-D-E-E-R-I-R-Q-G-G-C-E-A-Y-I-S-K-P-I-S-V-P-R-F-I-E-T-I-K-S-Y-L-G-D-A


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-A-T-A-E-I-E-E-I-P-A-L-L-K-P-G-Q-T-V-A-G-L-D-L-G-T-K-T-I-G-L-A-V-S-D-L-G-L-S-F-A-H-P-R-P-V-I-K-R-V-K-F-T-I-D-A-Q-V-L-L-K-A-L-E-T-D-K-V-G-V-I-V-I-G-L-P-M-N-M-D-G-T-A-G-P-R-V-Q-A-T-R-A-F-V-R-T-M-Q-P-L-T-D-L-P-F-V-F-W-D-E-R-L-S-T-V-A-A-E-R-A-L-I-G-M-D-V-S-R-G-K-R-A-D-R-I-D-S-A-A-A-A-F-I-L-Q-G-A-L-D-R-L-H-M-M-R-R-N-D-Y-D-A-G


### FUNCTION Required for optimal acid stress protection Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins ### SEQUENCE -M-I-K-A-L-F-N-K-N-T-A-L-A-A-V-T-I-L-A-L-S-G-G-A-M-A-E-S-A-K-T-H-K-T-D-M-A-K-K-K-V-S-E-L-T-C-E-D-F-N-G-L-E-E-S-F-K-P-T-V-V-G-W-V-V-G-F-N-K-K-G-K-E-E-D-A-V-I-D-V-D-G-I-E-T-V-T-P-A-I-I-E-A-C-K-Q-E-P-K-A-S-F-W-K-K-A-E-A-E-L-K-K-V-F


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-I-T-A-E-R-K-Q-A-L-I-K-E-Y-A-T-K-E-G-D-T-G-S-P-E-V-Q-V-A-V-L-S-E-R-I-A-N-L-T-E-H-F-K-G-H-K-N-D-N-H-S-R-R-G-L-L-K-L-V-S-Q-R-R-R-L-L-D-Y-V-K-G-V-D-H-A-R-Y-Q-A-L-I-T-R-L-G-L-R-R


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-R-S-H-D-T-K-G-S-G-G-L-S-Q-R-Q-L-R-V-G-E-Q-V-R-H-A-L-A-Q-V-L-Q-R-G-E-I-R-D-D-L-I-E-R-T-V-I-S-V-S-E-V-R-M-S-P-D-L-K-I-A-T-C-F-I-T-P-L-G-S-A-D-P-Q-A-V-I-K-A-L-A-S-H-A-K-F-I-R-G-R-V-A-P-S-L-A-Q-M-K-Y-M-P-E-F-R-F-R-P-D-T-S-F-D-N-F-S-K-I-D-A-L-L-R-S-P-E-V-A-R-D-L-S-H-D-D-D-E-D-G-G-A-D-E-A-P-R-N-G-D-E


### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It also specifically binds to its receptor SecA ### SEQUENCE -M-S-D-K-A-A-G-E-T-K-N-G-N-G-A-T-T-E-P-S-L-N-I-L-A-Q-Y-V-K-D-L-S-F-E-S-P-G-A-P-L-S-L-R-P-R-E-K-A-P-S-I-N-I-N-V-N-V-N-A-N-P-L-S-E-T-D-F-D-V-V-L-T-L-E-A-K-A-V-D-G-K-D-I-L-F-N-T-E-L-V-Y-G-G-V-F-R-I-Q-G-I-P-Q-E-H-M-L-P-L-L-F-I-E-C-P-R-L-L-F-P-F-A-R-Q-I-I-A-D-A-T-R-N-G-G-Y-P-P-L-M-I-D-P-I-D-F-A-Q-M-F-Q-Q-R-M-A-E-E-Q-A-K-S-A-V-K-S


### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-T-V-K-L-V-L-A-S-K-S-P-F-R-S-A-L-L-K-N-A-G-I-E-F-S-T-A-S-A-D-I-D-E-R-A-V-E-A-P-L-Y-E-S-G-A-T-P-E-D-V-A-Q-I-L-A-E-A-K-A-I-D-V-S-E-K-N-P-G-A-V-V-I-G-C-D-Q-T-L-S-L-G-D-E-I-F-H-K-P-H-D-M-E-A-A-R-R-Q-L-Q-K-F-S-G-K-T-H-Q-L-N-S-A-V-V-L-A-R-D-G-K-T-L-W-R-H-V-S-I-A-H-M-T-M-R-D-L-D-A-G-F-I-G-R-Y-L-G-R-V-G-D-I-A-L-S-S-V-G-A-Y-Q-V-E-G-P-G-I-Q-L-F-E-K-I-D-G-D-Y-F-T-I-V-G-L-P-L-L-P-L-L-A-E-L-R-R-E-K-C-I-D-G


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-I-K-T-G-G-K-Q-Y-R-V-A-A-N-D-L-I-K-V-E-K-V-A-G-E-A-G-D-I-V-E-F-A-E-V-L-M-V-G-S-T-I-G-A-P-T-V-A-G-A-L-V-T-A-E-V-V-E-Q-G-R-G-R-K-V-I-A-F-K-K-R-R-R-Q-N-S-K-R-T-R-G-H-R-Q-E-L-T-T-I-R-I-S-E-I-L-T-D-G-A-K-P-S-K-K-A-A-E-K-K-A-P-K-A-D-A-A-E-G-E-A-A-K-P-K-K-A-A-P-K-K-A-A-A-K-A-E-S-A-E


### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-S-K-H-K-G-P-T-G-A-M-V-D-P-E-S-L-P-Y-R-P-C-V-G-L-M-V-L-N-K-A-G-L-V-W-A-G-R-R-I-V-I-P-G-D-E-M-D-G-A-T-Q-L-W-Q-M-P-Q-G-G-I-D-K-G-E-D-P-A-Q-A-A-L-R-E-L-Y-E-E-T-G-M-T-S-V-S-L-L-E-E-A-S-D-W-I-N-Y-D-L-P-P-H-L-V-G-L-A-L-K-G-K-Y-R-G-Q-T-Q-K-W-F-A-Y-R-F-E-G-D-E-S-E-I-A-I-N-P-P-P-G-G-H-T-A-E-F-D-C-W-E-W-K-P-M-A-D-L-P-N-L-I-V-P-F-K-R-K-V-Y-E-Q-V-V-A-T-F-R-H-L-A-A


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-T-S-S-L-I-S-G-V-A-Q-R-Y-A-G-S-L-F-E-L-A-L-D-A-N-S-V-A-S-V-E-K-D-L-G-R-F-E-A-L-L-S-G-S-K-D-L-R-R-L-I-S-S-P-V-F-S-S-E-D-Q-L-H-A-I-G-A-I-A-D-K-A-G-I-K-G-L-V-G-N-F-L-R-V-V-A-Q-N-R-R-L-F-A-L-P-G-I-I-A-A-F-R-Q-I-A-A-E-H-R-G-E-I-S-A-D-V-V-S-A-H-E-L-T-S-A-Q-Q-N-E-L-K-A-T-L-K-G-V-A-G-K-D-V-T-I-N-V-T-V-D-P-S-I-L-G-G-L-I-V-K-M-G-S-R-Q-I-D-T-S-L-R-T-K-L-S-S-L-K-L-A-L-K-E-V-G


### FUNCTION Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide ### SEQUENCE -M-S-V-D-V-A-I-I-M-G-S-Q-S-D-W-E-T-M-R-H-A-A-H-T-L-E-A-L-G-I-S-F-D-A-R-I-V-S-A-H-R-T-P-D-R-L-V-A-F-A-K-G-A-K-A-E-G-F-K-V-I-I-A-G-A-G-G-A-A-H-L-P-G-M-A-A-A-M-T-P-L-P-V-F-G-V-P-V-Q-S-K-A-L-S-G-Q-D-S-L-L-S-I-V-Q-M-P-A-G-I-P-V-G-T-L-A-I-G-R-A-G-A-V-N-A-A-L-L-A-A-A-V-L-A-L-Y-D-E-A-L-A-A-R-L-D-E-W-R-K-A-Q-T-E-S-V-A-E-R-P-S-N-E-A


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-I-N-G-N-E-I-R-P-G-N-V-I-E-H-E-G-G-L-W-V-A-V-K-T-N-A-V-K-P-G-K-G-G-A-Y-N-Q-V-E-L-K-N-L-I-N-G-T-K-L-N-E-R-F-R-A-A-E-T-V-E-R-V-R-L-E-Q-K-D-F-S-F-L-Y-E-Q-G-E-A-L-I-F-M-D-T-E-T-Y-E-Q-L-E-L-Q-K-D-F-V-G-D-R-A-A-F-L-Q-D-G-M-M-V-T-V-E-L-Y-E-E-K-P-I-G-I-R-L-P-D-Q-V-T-L-A-I-T-E-A-D-P-V-V-K-G-Q-T-A-A-S-S-Y-K-P-A-V-L-E-N-G-I-R-I-L-V-P-P-F-I-A-S-G-E-R-V-I-V-D-T-N-E-L-T-Y-I-S-R-A


### FUNCTION Acts as a global negative controlling element, employing Fe as a cofactor to bind the operator of the repressed genes ### SEQUENCE -M-N-K-P-Y-T-K-P-D-Y-E-Q-E-L-R-R-A-G-V-R-I-T-R-P-R-R-I-I-L-N-I-L-N-E-T-E-D-H-P-D-A-L-E-I-F-R-R-A-V-E-E-D-D-S-I-S-L-S-T-V-Y-R-T-I-K-L-L-E-E-R-G-A-I-H-R-H-A-F-A-G-G-P-S-R-F-E-Q-A-S-G-A-H-H-D-H-I-I-D-M-D-S-G-D-V-V-E-F-H-S-D-K-I-E-K-L-Q-E-E-I-A-R-S-L-G-F-E-I-V-H-H-R-L-E-L-Y-C-K-K-L-K-S


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-T-P-L-D-V-M-W-V-G-L-G-G-G-V-G-S-L-G-R-W-W-I-G-R-I-V-G-E-Y-H-H-G-A-F-P-L-G-T-F-L-I-N-I-S-G-A-F-V-I-G-Y-L-S-V-L-F-G-V-D-W-H-D-R-Y-G-T-M-L-N-A-G-V-L-T-G-I-L-G-G-Y-T-T-F-S-S-M-Q-L-D-A-V-K-L-S-H-K-G-Q-G-G-L-A-V-F-Y-L-V-A-S-V-L-S-G-L-F-A-A-W-L-D-A-M-L-A-H-L-Q-G


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-A-G-Q-L-K-L-Q-V-P-A-G-A-A-N-P-S-P-P-I-G-P-A-L-G-Q-R-G-I-N-I-M-E-F-C-K-A-F-N-A-A-S-Q-E-M-E-K-G-S-P-I-P-V-L-I-T-Y-Y-Q-D-K-S-F-T-F-V-M-K-T-P-P-V-T-Y-F-L-K-K-A-A-N-L-K-S-G-S-K-T-P-G-K-A-S-A-G-T-I-T-R-D-K-V-R-A-I-A-E-A-K-M-K-D-L-N-A-A-D-V-E-A-A-M-R-M-I-E-G-S-A-R-S-M-G-L-E-V-V-G


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-D-R-A-E-K-R-E-F-V-A-W-L-N-G-A-F-K-E-S-G-S-V-V-V-A-H-Y-T-G-L-T-V-A-Q-M-S-D-L-R-S-K-M-R-D-A-G-G-S-V-K-V-A-K-N-R-L-A-K-I-A-L-Q-G-T-E-S-E-G-I-A-D-L-F-T-G-Q-T-V-V-A-Y-A-N-D-P-I-T-A-P-K-V-A-V-E-F-A-K-A-N-D-K-L-V-I-L-G-G-A-M-G-A-T-T-L-N-A-D-G-V-K-S-L-A-S-L-P-S-L-D-E-L-R-A-K-L-V-G-M-I-Q-T-P-A-Q-R-L-A-V-L-T-S-A-P-A-S-Q-I-A-R-V-I-G-A-H-A-R-K-N-E-A-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-R-H-K-A-E-K-R-E-I-N-P-D-P-K-F-G-D-L-V-I-T-K-F-M-N-A-V-M-L-H-G-K-K-S-V-A-E-S-I-V-Y-G-A-L-D-A-I-E-A-K-A-K-S-E-P-V-A-L-F-H-Q-A-L-D-N-V-A-P-H-I-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-D-V-R-P-E-R-R-Q-A-L-A-I-R-W-L-I-N-A-A-R-G-R-N-E-T-T-M-V-D-R-L-S-G-E-L-L-D-A-A-N-N-R-G-S-A-V-K-K-R-E-D-T-H-R-M-A-E-A-N-R-A-F-S-H-Y-R-W


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-T-D-L-R-H-Y-D-V-I-V-S-P-V-I-T-E-K-S-T-M-V-S-E-H-N-Q-V-V-F-N-V-A-R-K-A-T-K-P-E-I-K-A-A-V-E-A-L-F-G-V-K-V-T-A-V-N-T-A-V-R-K-G-K-V-K-R-F-R-G-L-V-G-R-Q-S-D-V-K-K-A-I-V-T-L-A-E-G-Q-S-I-D-V-S-T-G-L


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-G-K-A-K-A-P-R-Q-L-K-D-N-E-A-K-A-V-A-R-T-L-R-V-S-P-Q-K-L-N-L-V-A-S-M-I-R-G-K-K-V-N-A-A-L-A-D-L-T-F-S-R-K-R-I-A-G-T-V-K-K-T-L-E-S-A-I-A-N-A-E-N-N-H-D-L-D-V-D-A-L-I-V-A-E-A-Y-V-G-K-S-I-V-M-K-R-F-H-V-R-G-R-G-R-A-S-R-I-E-K-P-F-S-H-L-T-I-V-V-R-E-V-A-E-K-G-E-A-A


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-M-Q-P-K-R-T-K-F-R-K-Q-F-K-G-R-I-H-G-N-S-K-G-G-T-D-L-N-F-G-A-F-G-L-K-A-L-E-P-E-R-V-T-A-R-Q-I-E-A-A-R-R-A-I-T-R-H-M-K-R-A-G-R-V-W-I-R-I-F-P-D-L-P-V-T-S-K-P-T-E-V-R-M-G-K-G-K-G-S-V-D-Y-W-A-C-R-V-A-P-G-R-V-M-F-E-L-D-G-V-P-E-D-V-A-R-E-A-L-R-L-G-A-A-K-L-P-I-K-T-R-F-I-Q-R-I-A-E


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-V-L-Q-G-V-V-V-S-D-K-N-D-K-T-V-V-V-K-V-E-R-R-Y-S-H-P-L-L-Q-K-T-V-R-Q-S-K-K-Y-K-A-H-D-E-N-N-Q-F-K-V-G-D-F-V-S-I-Q-E-S-A-P-I-S-K-D-K-R-W-V-V-L-T-S-E-A-A-G


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-T-N-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-S-V-G-D-I-I-V-V-S-I-K-E-A-I-P-R-G-R-V-K-K-G-D-V-M-K-A-V-V-V-R-T-A-K-D-I-R-R-P-D-G-S-V-I-R-F-D-N-N-A-A-V-L-I-D-N-K-K-E-P-I-G-T-R-I-F-G-P-V-P-R-E-L-R-A-K-N-H-M-K-I-I-S-L-A-P-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-K-I-R-K-G-D-S-V-V-V-L-S-G-K-D-K-G-R-K-G-E-V-L-K-V-M-P-K-D-E-Q-A-L-V-S-G-I-N-I-V-K-R-H-Q-R-Q-T-Q-T-Q-E-A-G-I-I-S-K-E-A-P-I-H-L-S-N-L-A-I-A-D-P-K-D-G-K-P-T-R-V-G-F-R-V-E-D-G-K-K-V-R-V-A-K-R-S-G-A-L-I-D-G


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-E-A-K-A-L-P-R-F-K-K-L-Y-Q-D-N-I-R-K-A-L-L-E-E-F-K-Y-D-N-E-M-Q-I-P-R-I-T-K-V-V-L-N-M-G-V-G-E-A-T-G-D-S-K-K-P-A-V-A-A-E-D-L-A-M-I-A-G-Q-K-A-V-V-T-R-A-R-N-S-I-A-T-F-K-L-R-E-G-M-P-I-G-A-K-V-T-L-R-Q-D-R-M-Y-E-F-L-D-R-L-I-T-I-A-L-P-R-V-R-D-F-R-G-L-N-P-K-S-F-D-G-R-G-N-Y-A-M-G-I-K-E-H-I-V-F-P-E-I-N-Y-D-K-V-D-Q-I-W-G-M-D-I-I-V-C-T-T-A-K-T-D-D-E-A-R-S-L-L-R-A-F-N-F-P-F-R-Q


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-V-S-D-P-L-G-D-M-L-T-R-I-R-N-A-V-G-R-K-K-T-K-V-S-T-P-A-S-K-L-R-A-R-V-L-D-V-L-Q-A-E-G-Y-I-R-G-Y-T-Q-S-E-F-E-N-G-K-A-E-I-E-I-E-L-K-Y-Y-E-G-V-P-V-I-R-E-I-T-R-V-S-K-P-G-R-R-V-Y-V-S-V-K-S-I-P-Q-V-A-N-G-L-G-I-S-I-L-S-T-P-K-G-V-M-A-D-H-E-A-R-E-Q-N-V-G-G-E-L-L-C-R-I-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-P-V-P-V-P-A-G-V-T-A-S-V-E-G-Q-T-V-K-A-K-G-A-K-G-E-L-S-F-V-V-H-D-E-V-L-V-K-M-E-D-G-A-V-R-V-D-P-R-D-Q-S-K-E-A-R-S-K-W-G-M-S-R-T-M-I-S-N-I-F-V-G-V-K-D-G-F-E-K-K-L-E-I-S-G-V-G-Y-R-A-A-M-Q-G-K-N-L-Q-L-S-L-G-F-S-H-E-V-V-Y-D-V-P-A-G-I-T-V-A-V-P-K-P-T-E-I-V-V-T-G-I-D-K-Q-Q-V-G-Q-V-A-A-E-I-R-E-Y-R-G-P-E-P-Y-K-G-K-G-V-K-Y-A-G-E-K-I-V-R-K-E-G-K-K-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-A-S-P-K-E-T-L-Q-R-R-A-A-R-V-R-R-Q-V-K-A-V-A-N-G-R-P-R-L-S-V-H-R-S-S-K-N-I-Y-A-Q-I-I-D-D-V-R-G-V-T-L-A-A-A-S-T-L-D-G-D-L-K-G-K-L-K-T-G-A-D-S-A-A-A-A-A-V-G-K-L-V-A-E-R-A-V-K-A-G-V-K-D-V-V-F-D-R-S-A-F-I-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-G-G-L-S-F


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-D-L-R-D-K-P-G-S-V-K-A-R-K-R-V-G-R-G-I-G-S-G-T-G-K-T-G-G-R-G-V-K-G-Q-K-S-R-S-G-V-S-I-N-G-F-E-G-G-Q-M-P-I-Y-R-R-L-P-K-R-G-F-T-N-I-F-A-K-S-F-N-V-V-S-L-G-R-I-Q-A-A-I-D-A-G-K-L-D-A-K-A-V-V-N-L-D-S-L-K-A-A-G-V-I-R-R-A-K-D-G-V-R-I-L-S-D-G-E-L-K-A-K-V-A-F-E-V-A-G-A-S-K-A-A-V-E-K-I-E-K-A-G-G-S-I-K-L-P-E-A-A-A-E


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-R-R-I-N-T-I-M-Q-G-K-T-N-G-G-N-G-P-E-S-G-T-V-V-V-T-R-T-Q-P-K-T-R-K-P-S-L-Y-R-V-L-L-L-N-D-D-Y-T-P-M-E-F-V-V-H-V-L-Q-R-F-F-Q-K-N-L-D-D-A-T-R-I-M-L-H-V-H-N-H-G-V-G-E-C-G-V-F-T-Y-E-V-A-E-T-K-V-S-Q-V-M-D-F-A-R-Q-N-Q-H-P-L-Q-C-V-M-E-K-K


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-D-A-F-D-I-N-D-L-K-R-R-M-E-G-A-V-N-A-L-K-H-D-L-G-G-L-R-T-G-R-A-S-A-S-L-L-E-P-I-T-I-E-A-Y-G-S-T-M-P-I-N-Q-V-A-N-I-S-V-P-E-S-R-M-L-S-V-S-V-W-D-K-S-M-V-G-A-V-E-R-A-I-R-D-S-G-L-G-L-N-P-I-T-D-G-M-T-L-R-I-P-L-P-E-L-N-E-Q-R-R-K-E-L-V-K-I-A-H-Q-Y-A-E-Q-G-R-I-A-A-R-H-V-R-R-D-G-M-D-Q-L-K-K-L-E-K-D-S-V-I-S-Q-D-E-S-R-V-L-S-E-K-V-Q-K-L-T-D-D-T-I-A-E-M-D-K-I-V-A-V-K-E-G-E-I-M-Q-V


### FUNCTION Involved in unsaturated fatty acids biosynthesis Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs ### SEQUENCE -M-S-D-D-N-Q-T-K-L-E-A-A-D-I-Q-A-L-L-A-V-L-P-H-R-Y-P-F-L-L-I-D-R-I-V-D-I-D-G-D-V-S-A-T-G-I-K-N-V-T-I-N-E-P-H-F-T-G-H-F-P-E-N-P-I-M-P-G-V-L-I-V-E-A-M-A-Q-T-A-G-A-I-S-L-L-Q-R-K-T-G-R-P-G-V-V-Y-F-M-T-I-D-N-A-K-F-R-R-P-V-V-P-G-D-R-L-L-L-H-V-K-K-I-K-Q-R-A-N-I-S-K-Y-E-C-V-A-E-V-D-G-V-K-V-A-E-A-E-V-A-A-M-I-S-V-A-D-E-N-L


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-V-N-K-V-I-L-V-G-N-L-G-A-D-P-E-I-R-R-L-N-S-G-D-M-V-A-N-L-R-I-A-T-S-E-S-W-R-D-R-Q-T-G-E-R-K-D-R-T-E-W-H-S-V-V-I-F-N-E-N-L-A-K-V-A-E-Q-Y-L-K-K-G-A-K-V-Y-I-E-G-A-L-Q-T-R-K-W-Q-D-Q-N-G-N-D-R-Y-S-T-E-I-V-L-Q-K-F-R-G-E-L-Q-M-L-D-S-R-S-E-G-G-E-G-R-S-F-G-G-G-G-N-R-N-Q-M-S-D-Y-S-G-G-G-G-D-F-G-S-S-G-P-S-S-G-S-S-G-G-F-S-R-D-L-D-D-E-I-P-F


### FUNCTION PPIases accelerate the folding of proteins It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ### SEQUENCE -M-S-F-I-R-S-A-L-A-A-A-A-F-V-A-L-S-I-G-A-V-Q-T-A-S-A-A-D-P-E-N-T-V-I-L-K-L-K-D-G-D-V-A-L-E-L-R-P-D-L-A-P-K-H-V-A-Q-I-K-K-L-V-R-E-G-A-Y-N-G-V-A-F-H-R-V-I-P-G-F-M-A-Q-T-G-D-V-K-F-G-N-M-D-K-G-F-D-A-A-R-V-G-T-G-G-S-N-Y-P-D-L-P-A-E-F-S-K-E-P-F-V-R-G-T-V-G-M-A-R-S-Q-N-P-N-S-A-N-S-Q-F-F-I-M-F-D-D-G-P-F-L-N-G-Q-Y-T-V-V-G-K-V-V-S-G-M-D-A-V-D-K-I-K-K-G-S-E-A-E-N-G-A-V-K-N-P-D-K-I-I-K-A-T-I-E-A-D-T-K


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-A-T-F-S-Q-K-P-A-E-V-V-K-K-W-V-L-I-D-A-E-G-L-V-V-G-R-L-A-S-L-V-A-N-R-L-R-G-K-H-K-A-T-F-T-P-H-V-D-D-G-D-N-V-I-I-I-N-A-D-K-V-V-L-T-G-K-K-Y-T-D-K-K-Y-Y-W-H-T-G-H-P-G-G-I-K-E-R-T-A-R-Q-I-L-E-G-R-F-P-E-R-V-L-E-K-A-I-E-R-M-I-P-R-G-P-L-G-R-R-Q-M-K-N-L-R-V-Y-A-G-P-N-H-Q-H-E-A-Q-Q-P-E-V-L-D-V-A-A-L-N-R-K-N-K-G-N-A


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-N-S-I-P-E-G-R-P-T-P-N-L-P-R-T-A-N-K-R-G-V-A-R-L-A-A-V-Q-A-L-Y-Q-M-D-V-A-G-T-G-V-M-E-V-V-A-E-Y-E-A-F-R-L-G-K-E-V-D-G-T-Q-Y-L-D-A-D-P-Q-W-F-R-A-I-V-A-G-V-V-E-D-Q-L-K-L-D-P-M-I-H-Q-A-L-T-E-D-W-P-L-S-R-L-D-S-T-L-R-A-I-L-R-A-G-A-W-E-L-K-A-R-K-D-V-P-T-A-V-I-V-S-E-Y-V-D-I-A-K-A-F-Y-T-E-D-E-P-K-L-V-N-A-V-L-D-R-L-A-L-V-I-R-G-E-S-R-G-A-K-P-R-H-K-S


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-C-V-D-K-V-E-N-R-F-E-L-V-L-L-A-G-H-R-A-R-Q-I-S-Q-G-V-P-I-T-V-D-R-D-N-D-K-N-P-V-V-A-L-R-E-I-A-D-E-T-L-S-P-D-D-L-K-E-D-L-I-H-S-L-Q-K-H-V-E-V-D-E-P-E-A-A-P-A-Q-I-A-N-A-A-E-E-I-A-E-G-I-A-E-A-G-E-E-D-V-V-T-F-D-R-M-S-E-E-E-L-L-A-G-I-E-G-L-V-A-P-E-K-N-D-G-F


### FUNCTION Repressor involved in the biosynthesis of the osmoprotectant glycine betaine It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine ### SEQUENCE -M-P-K-I-G-M-E-P-L-R-R-R-E-L-I-D-A-A-I-R-T-I-G-Q-R-G-S-L-D-V-T-V-A-Q-I-A-H-E-A-G-V-S-P-A-L-A-H-H-Y-F-G-G-K-D-K-L-I-L-A-T-M-R-H-L-L-R-E-L-G-R-D-L-N-A-A-I-K-Q-A-N-A-P-H-E-R-I-A-A-I-I-A-V-N-F-S-A-A-Q-F-A-Q-E-T-I-A-A-W-L-T-F-Y-V-H-A-Q-Q-S-D-D-I-K-R-L-L-R-I-Y-A-R-R-L-H-S-N-L-V-F-A-L-E-Q-L-T-S-R-A-R-A-N-R-I-A-E-G-A-G-A-M-I-D-G-L-Y-I-R-H-A-L-G-A-D-A-P-D-A-A-S-A-I-A-L-V-E-D-Y-I-A-I-Q-L-S-G-Q-P-S-A-E-N


### FUNCTION Catalyzes the hydrolysis of 5-hydroxyisourate ### SEQUENCE -M-G-K-L-S-T-H-V-L-D-T-A-H-G-T-P-A-A-A-M-R-V-E-L-Y-R-I-A-A-S-G-T-P-E-L-L-K-R-V-V-T-N-L-D-G-R-T-D-A-P-L-L-S-G-D-K-M-R-T-G-I-Y-E-L-Q-F-H-V-A-E-Y-F-E-G-R-G-A-E-L-A-H-E-P-F-L-D-L-I-P-I-R-F-G-I-A-D-E-D-G-N-Y-H-V-P-L-L-V-S-P-W-S-Y-S-T-Y-R-G-S


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-L-Y-E-H-V-L-L-A-R-Q-D-I-S-Q-Q-Q-V-D-A-L-V-E-Q-F-K-G-V-L-E-A-N-G-G-K-F-G-K-V-E-N-W-G-L-R-P-L-T-Y-R-I-K-K-N-R-K-A-Y-Y-T-L-V-N-I-D-A-P-A-A-A-V-A-E-M-E-R-Q-M-R-I-N-E-D-V-L-R-F-L-T-V-R-V-E-E-H-E-E-G-Q-S-A-M-L-T-R-R-D-D-R-R-E-R-D-G-D-D-R-P-R-R-R-E-G-G-F-D-R-G-D-R-G-D-R-G-P-R-R-P-R-D-T-E-A-G-E-G-A


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-E-V-I-L-L-E-R-I-G-R-L-G-Q-M-G-D-T-V-K-V-K-D-G-Y-A-R-N-F-L-L-P-Q-G-K-A-L-R-A-N-E-A-N-K-K-K-F-E-G-Q-R-A-Q-L-E-A-Q-N-L-E-R-K-N-E-A-Q-A-V-A-D-K-L-N-G-E-S-F-I-V-V-R-S-A-G-E-T-G-Q-L-Y-G-S-V-S-T-R-D-I-A-E-I-I-T-A-D-G-F-T-L-H-R-N-Q-V-E-L-N-H-P-I-K-T-I-G-L-H-E-V-S-V-S-L-H-P-E-V-Q-V-K-V-M-V-N-I-A-R-S-T-E-E-A-E-R-Q-A-K-G-E-D-L-T-S-I-E-A-I-Y-G-I-E-E-Q-P-L-S-E-E-V-F-D-D-E-D-E-A-E-D-Q-A


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-D-A-T-F-W-A-F-I-A-L-V-I-F-V-V-I-V-V-Y-M-K-V-P-G-M-I-G-R-T-L-D-E-R-A-D-R-I-K-K-E-L-E-E-A-R-T-L-R-E-E-A-Q-Q-L-L-A-E-Y-H-R-K-R-K-E-A-E-K-E-A-G-D-I-V-A-S-A-E-R-E-A-K-A-L-L-E-E-A-K-R-A-T-E-E-Y-V-A-R-R-N-K-L-A-E-Q-K-I-A-T-A-E-T-D-A-I-N-A-V-R-A-S-A-V-D-L-A-V-A-A-A-G-S-I-L-A-E-K-V-D-A-K-A-A-G-N-L-F-N-D-A-L-A-Q-V-K-S-H-L-N


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-Q-E-F-A-L-K-G-N-M-V-D-L-A-I-G-V-I-I-G-G-A-F-G-G-L-V-N-S-I-V-N-D-I-I-M-P-I-I-G-L-I-T-G-G-I-D-F-S-N-M-F-I-Q-L-A-G-D-P-K-T-T-L-A-A-A-R-E-A-G-A-T-I-A-Y-G-N-F-I-T-L-L-I-N-F-L-I-I-A-W-V-L-F-L-V-V-K-L-M-N-R-L-K-K-R-E-E-A-K-P-A-P-A-A-P-S-E-E-V-L-L-T-E-I-R-D-I-L-A-K-Q-Q-K-A


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-V-L-E-F-P-G-V-V-T-E-L-L-P-N-A-M-F-R-V-K-L-E-N-E-H-E-I-I-A-H-T-A-G-R-M-R-K-N-R-I-R-V-L-A-G-D-K-V-L-V-E-M-T-P-Y-D-L-T-K-G-R-I-T-Y-R-L-K


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-I-K-S-E-L-V-Q-I-I-A-S-R-N-P-H-L-F-Q-R-D-V-E-N-I-V-G-A-V-F-D-E-I-T-N-A-L-A-E-G-N-R-V-E-L-R-G-F-G-A-F-S-V-K-N-R-P-A-R-S-G-R-N-P-R-T-G-E-T-V-D-V-E-E-K-W-V-P-F-F-K-T-G-K-E-L-R-D-R-L-N-G-A-V


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-F-G-T-D-P-T-P-D-G-L-A-N-P-P-I-D-D-L-M-K-H-A-D-S-K-Y-A-L-A-I-F-A-A-K-R-A-R-Q-I-N-S-Y-F-T-Q-L-N-E-G-L-L-Q-N-I-G-P-L-V-E-Y-Q-N-N-E-K-P-L-S-I-A-F-R-E-I-D-E-G-L-L-E-E-T-L-G-E-D-D-A-N-E-G-N


### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-Q-Q-G-I-H-P-D-Y-H-P-V-E-V-T-C-S-C-G-N-T-F-V-T-R-T-A-G-K-E-D-H-M-F-V-D-V-C-S-Q-C-H-P-F-Y-T-G-K-Q-K-I-L-D-T-G-G-R-V-A-R-F-E-K-R-Y-G-K-K-S-K


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-G-T-N-P-R-A-A-R-I-A-A-L-I-Q-R-V-V-A-S-S-I-E-R-E-L-H-D-K-R-L-A-S-I-T-V-T-E-V-R-V-T-N-D-L-Q-I-A-K-V-Y-W-T-Q-L-G-H-E-G-H-E-E-G-E-R-K-R-A-Q-Q-A-L-D-Q-A-K-G-H-L-R-S-L-V-G-H-K-A-G-L-R-L-T-P-Q-L-Q-F-V-F-D-E-V-P-G-E-A-H-E-I-E-D-I-L-A-V-A-K-K-R-D-E-E-L-A-R-A-R-A-T-A-Q-Y-A-G-D-A-D-P-Y-K-H-D-D-E-P-S-D-D-F-E-D-D-S-D-E-E


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-L-A-G-V-D-I-P-N-E-K-R-I-E-I-A-L-T-Y-I-F-G-V-G-R-T-R-A-K-E-T-L-A-A-T-G-I-S-P-D-I-R-V-K-D-L-T-D-E-Q-L-I-T-L-R-D-Y-L-E-A-N-Y-K-I-E-G-D-L-R-R-E-V-D-A-D-I-R-R-K-I-Q-I-N-C-Y-Q-G-Q-R-H-R-K-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-K-R-T-V-A-G-K-K-K-A-T-K


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-G-V-I-E-V-E-G-Q-V-V-E-A-L-P-N-A-M-F-R-V-E-L-E-N-K-H-I-V-L-A-T-I-S-G-K-M-R-K-N-Y-I-R-I-L-P-Q-D-R-V-V-L-E-M-S-P-Y-D-L-N-R-G-R-I-T-Y-R-Y-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-D-N-E-I-L-Q-M-H-D-L-K-P-A-P-G-A-K-K-D-R-T-R-V-G-R-G-E-G-S-K-G-K-T-S-G-R-G-A-K-G-Q-T-K-R-N-H-V-R-P-G-F-E-G-G-Q-L-P-L-Y-M-R-L-P-K-L-R-G-F-K-N-P-F-K-V-E-F-Q-V-I-N-I-A-R-L-V-E-L-F-P-E-G-G-E-V-A-V-A-D-L-I-A-K-G-A-V-R-D-N-A-P-V-K-V-L-G-D-G-E-T-T-V-A-F-T-L-K-G-V-K-A-S-A-S-A-K-S-K-I-E-A-A-G-G-S-V-S-E-D


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-V-A-I-L-G-K-G-K-K-V-A-L-K-R-R-H-A-R-I-R-K-R-I-S-G-T-P-E-R-P-R-L-V-V-T-R-S-N-R-H-M-V-A-Q-V-V-D-D-T-K-G-I-T-L-V-S-A-S-T-L-Q-A-D-F-A-G-F-E-G-T-K-T-E-A-A-K-K-V-G-E-L-I-A-E-K-A-K-A-A-G-I-T-A-V-V-F-D-R-G-G-N-K-Y-T-G-R-V-A-A-V-A-D-G-A-R-E-G-G-L-A-L


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-A-S-H-I-G-K-L-P-I-A-I-P-A-G-V-E-V-K-I-E-G-Q-N-F-S-A-K-G-A-K-G-S-D-S-Y-V-V-P-E-G-I-T-A-A-V-E-G-N-E-I-V-L-T-A-A-D-D-L-R-P-T-R-A-K-H-G-L-A-R-S-I-M-A-G-M-V-K-G-V-H-D-G-Y-S-K-T-L-E-I-V-G-T-G-Y-R-A-V-A-K-G-Q-G-I-E-F-F-L-G-Y-S-H-T-I-T-V-N-P-P-E-G-I-T-L-K-V-T-D-A-N-H-V-V-V-E-G-T-D-K-Q-V-V-G-Q-V-A-A-N-I-R-K-L-R-A-P-E-P-Y-K-G-K-G-I-K-Y-S-D-E-R-I-L-R-K-A-G-K-A-G-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-I-A-D-M-L-T-R-L-R-N-A-S-A-A-K-H-E-T-V-D-M-P-Y-S-K-F-K-A-N-I-A-E-I-L-K-R-E-G-Y-I-K-D-F-T-A-K-E-A-K-V-G-Q-T-L-E-V-T-L-K-Y-G-P-N-G-E-R-S-I-Q-G-I-K-R-I-S-K-P-G-L-R-R-Y-A-K-S-D-S-L-P-M-P-L-G-G-L-G-I-A-I-I-S-T-S-S-G-L-L-T-Q-K-E-C-L-D-R-G-I-G-G-E-I-V-A-F-V-W


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-A-L-K-N-K-A-A-G-K-P-K-F-K-V-R-A-Y-T-R-C-Q-V-C-G-R-P-H-S-V-Y-R-K-F-G-L-C-R-I-C-L-R-E-K-A-H-R-G-E-L-P-G-V-T-K-S-S-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-D-T-T-V-E-A-P-A-T-P-R-L-K-V-K-Y-N-E-Q-I-I-P-E-L-E-K-E-F-K-Y-S-N-P-M-Q-V-A-R-V-Q-K-V-V-V-S-M-G-V-G-A-A-A-R-D-S-K-L-I-E-G-A-V-K-D-L-T-L-I-T-G-Q-K-P-K-I-T-K-A-K-K-S-V-A-Q-F-H-L-R-E-G-Q-A-I-G-A-Y-V-T-L-R-G-D-R-M-W-E-F-L-D-R-L-L-T-L-A-L-P-R-I-R-D-F-R-G-I-N-G-H-Q-F-D-G-Q-G-N-Y-N-F-G-L-T-E-Q-S-M-F-H-E-I-D-P-D-S-I-D-H-V-R-G-M-D-I-T-V-V-T-S-T-K-D-D-K-E-A-Y-A-L-L-K-H-L-G-F-P-F-K-E-N


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-K-S-G-D-L-V-K-V-I-R-G-K-D-R-G-K-E-G-T-V-K-Q-V-L-S-N-D-R-L-I-V-E-G-V-Q-I-V-K-K-H-V-R-A-T-Q-Q-G-Q-Q-A-G-I-V-S-T-E-A-P-I-H-R-S-N-V-M-V-I-D-P-E-T-K-Q-P-T-R-V-G-I-T-V-K-E-E-A-R-D-G-K-V-K-T-V-R-V-R-V-A-K-K-S-G-K-E-L-A


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-H-V-A-D-N-T-G-A-K-E-L-L-A-I-R-V-L-G-G-S-K-R-R-Y-A-G-I-G-D-V-I-V-A-S-V-K-D-A-I-P-G-G-S-V-K-K-G-D-V-V-K-A-V-V-V-R-T-V-K-E-S-R-R-A-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-L-G-S-G-R-E-P-K-G-T-R-I-F-G-P-V-G-R-E-L-R-E-H-K-F-M-K-I-V-S-L-A-P-E-V-I


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-E-E-R-N-F-R-K-V-R-R-G-Y-V-V-S-D-K-M-D-K-T-I-T-V-E-L-E-Q-R-S-T-H-P-L-Y-G-K-V-V-R-S-T-S-K-V-K-A-H-D-E-H-N-D-A-H-I-G-D-L-V-S-I-M-E-T-R-P-L-S-K-T-K-R-W-R-L-E-S-I-I-E-R-A-K


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-I-P-K-R-T-K-Y-R-K-Q-H-R-P-V-R-S-G-M-S-K-G-G-N-E-I-N-F-G-D-F-A-I-Q-S-L-A-P-A-Y-V-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-I-K-R-G-G-R-V-W-I-T-I-F-P-D-R-P-L-T-K-H-P-L-G-A-R-M-G-S-G-K-G-A-P-E-F-W-I-A-N-V-R-P-G-R-V-M-F-E-I-G-G-V-S-E-D-I-A-K-E-A-L-R-R-A-I-D-K-L-P-M-K-C-R-I-I-A-R-E-G-G-D-I


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-I-A-R-H-V-R-V-T-P-R-K-A-R-R-M-V-D-L-I-R-G-K-K-A-T-E-A-V-T-I-L-K-F-A-P-Q-A-A-A-L-P-V-R-K-T-L-E-S-A-I-A-N-A-R-V-K-A-D-K-A-G-E-P-F-R-E-N-D-L-Y-I-K-E-T-Y-V-D-E-G-V-T-L-K-R-F-R-A-R-A-Q-G-R-A-A-R-I-N-K-R-T-S-H-I-T-V-V-V-A-N-K-E-G-A-R


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-I-K-K-G-P-F-V-D-A-H-L-Q-K-K-V-D-E-Q-N-E-K-G-T-K-N-V-I-K-T-W-S-R-R-S-M-I-T-P-D-F-I-G-H-T-F-A-V-H-D-G-R-K-H-V-P-V-F-V-T-E-A-M-V-G-H-K-L-G-E-F-A-P-T-K-T-F-K-G-H-V-K-D-D-K-K-A-R-R


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-V-A-I-H-K-P-A-H-D-V-I-L-K-P-V-V-S-E-K-S-Y-A-A-S-D-R-G-Q-Y-T-F-V-V-A-P-D-A-N-K-V-Q-I-K-Q-A-I-E-E-I-F-K-V-K-V-T-N-V-N-T-L-N-R-A-G-K-K-Q-R-T-R-T-G-F-G-Q-R-A-S-Q-K-R-A-I-V-T-V-A-E-G-Q-T-I-D-I-F-G-N


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-G-Q-K-I-R-I-R-L-K-S-Y-D-H-E-V-I-D-Q-S-A-K-K-I-V-E-T-V-T-N-A-G-A-T-V-V-G-P-V-P-L-P-T-E-K-N-V-F-C-V-I-R-S-P-H-K-Y-K-D-S-R-E-H-F-E-M-R-T-H-K-R-L-I-D-I-V-D-P-T-P-K-A-V-D-S-L-M-H-I-D-L-P-A-D-V-N-I-E-I-K-L


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-T-P-K-P-A-D-L-T-H-D-W-Y-V-I-D-A-T-D-V-V-L-G-R-L-A-T-Q-A-A-I-L-L-R-G-K-N-K-P-T-Y-A-P-H-A-D-S-G-N-H-V-I-I-I-N-A-D-K-I-A-L-T-G-N-K-M-G-K-E-L-Y-S-H-S-G-R-P-G-G-L-R-R-D-S-Y-A-E-L-L-E-K-N-P-E-R-I-I-K-N-A-V-K-G-M-L-P-K-N-R-L-A-K-V-Q-L-D-R-L-R-I-F-R-G-A-E-H-P-H-T-P-Q-K-P-Q-V-F-E-I-A-Q-V-S-Q-Q-A-K


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-Y-T-N-D-E-L-L-E-A-F-G-E-M-T-L-V-E-L-S-E-F-V-K-A-F-E-E-K-F-D-V-E-A-A-A-P-V-A-A-V-A-A-V-A-G-A-A-A-P-A-E-E-E-K-D-E-F-D-V-I-L-S-A-V-G-D-K-K-I-Q-V-I-K-A-V-R-A-I-T-N-L-G-L-A-E-A-K-A-L-V-D-G-A-P-K-A-V-L-E-K-A-K-K-E-D-A-E-K-A-K-A-Q-L-E-E-A-G-A-S-V-E-L-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-K-R-P-E-K-E-A-V-V-A-Q-L-T-E-E-F-R-N-A-D-A-V-Y-L-T-E-Y-R-G-L-T-V-P-Q-I-S-D-L-R-E-K-L-G-R-D-T-S-Y-T-V-A-K-N-T-L-A-R-I-A-A-K-E-A-G-I-E-G-L-D-E-I-L-S-G-P-T-A-I-T-F-V-K-G-D-F-I-E-A-A-K-V-I-R-D-F-A-K-D-N-K-A-L-V-I-K-G-A-A-A-D-G-T-V-Y-D-A-E-G-A-K-K-L-A-D-L-K-S-R-P-Q-L-L-A-E-F-A-G-D-I-K-A-S-M-A-K-A-A-Y-L-F-N-A-L-P-T-K-A-V-R-T-I-D-A-L-R-E-K-Q-E-K-A-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-A-E-E-K-Q-E-I-I-A-K-Y-A-T-H-E-G-D-T-G-S-P-E-V-Q-V-A-L-L-S-K-R-I-A-D-L-T-E-H-L-K-E-H-K-H-D-H-H-S-R-R-G-M-Q-L-M-I-G-D-R-R-R-L-L-D-Y-L-K-R-V-D-I-N-R-Y-R-S-L-I-E-R-L-G-L-R-R


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-L-I-D-Q-A-K-E-Q-M-A-K-T-V-E-N-T-K-E-N-F-S-G-I-R-T-G-R-A-N-P-A-L-L-N-G-I-T-V-D-Y-Y-G-A-P-T-P-I-K-A-V-A-S-I-G-V-P-E-P-R-T-L-S-V-T-P-F-D-A-S-Q-A-G-A-V-E-K-A-L-R-N-S-D-L-G-I-S-P-N-R-D-G-N-V-I-R-L-T-M-P-E-L-T-E-D-R-R-K-E-Y-V-K-L-A-K-G-K-A-E-D-G-K-V-A-V-R-N-I-R-R-K-T-K-E-T-I-D-K-A-V-K-D-G-E-M-G-E-D-E-G-D-R-L-L-K-D-L-D-K-V-T-K-S-V-T-D-E-I-D-T-L-L-E-T-K-Q-K-E-I-M-E-V


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-I-R-E-I-R-V-V-P-D-P-V-L-R-T-P-C-D-E-I-K-E-I-T-P-A-V-R-R-L-V-D-D-L-L-E-T-V-D-D-P-G-R-A-G-L-S-A-N-Q-I-G-V-S-L-R-A-F-S-Y-N-I-D-G-K-V-G-Y-V-L-N-P-V-L-E-E-K-S-G-E-Q-Y-G-D-E-G-C-L-S-V-P-G-L-W-Y-K-T-R-R-A-D-Y-A-R-V-R-G-I-D-L-D-G-N-E-V-V-L-E-G-S-G-L-M-G-R-M-L-Q-H-E-C-D-H-L-D-G-H-V-Y-L-D-R-L-E-K-E-E-R-R-E-A-L-R-Y-M-R-N-R-Q-A-K


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-A-F-D-E-T-Y-N-E-P-E-S-T-E-V-L-V-K-S-L-D-P-E-H-P-A-Q-L-H-Y-A-H-A-G-D-A-G-A-D-L-I-T-T-V-D-V-T-L-K-P-F-E-R-A-L-V-P-T-G-V-A-I-A-L-P-A-G-Y-V-A-L-V-H-P-R-S-G-L-A-A-K-Q-G-V-T-V-L-N-A-P-G-T-V-D-A-G-Y-R-G-E-I-K-V-P-L-I-N-L-D-P-K-H-T-A-V-F-H-P-G-D-R-I-A-Q-L-V-I-Q-R-Y-V-E-A-R-F-I-P-A-E-T-L-P-G-S-D-R-A-E-R-G-F-G-S-T-G-V-A-S


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-A-V-N-A-H-K-K-R-R-V-V-L-E-R-A-S-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-L-L-H-S-F-N-Y-N-F-R-D-R-K-A-R-K-G-D-F-R-K-L-W-I-Q-R-I-N-A-A-V-R-A-E-G-I-T-Y-N-R-F-I-Q-G-L-R-L-A-G-I-E-L-D-R-R-A-L-A-E-I-A-V-S-D-P-N-T-F-K-T-I-V-D-A-A-K-A-A-L-P-E-D-V-N-A-P-V-E-A


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-Q-N-P-D-T-K-V-I-D-T-R-I-S-D-D-G-H-S-I-R-R-R-R-V-C-P-K-C-S-K-R-F-T-T-V-E-T-S-M-L-L-V-T-K-R-S-G-G-V-E-P-F-S-R-D-K-V-I-S-G-V-R-K-A-C-Q-G-R-P-V-R-E-E-D-L-K-L-L-G-Q-K-V-E-E-D-L-R-S-R-G-L-A-E-V-T-S-D-E-V-G-K-A-I-L-K-P-L-R-D-L-D-V-V-A-Y-L-R-F-A-S-V-Y-Q-N-F-A-G-L-E-D-F-Q-S-A-I-D-G-L-R-E


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-P-K-K-K-V-S-A-L-I-K-L-Q-I-Q-A-G-K-A-N-P-A-P-P-L-G-P-A-L-G-S-H-G-V-N-I-M-D-F-C-K-A-Y-N-A-Q-T-Q-D-K-M-G-Q-V-I-P-V-E-I-T-V-Y-E-D-R-S-F-T-F-V-L-K-T-P-P-A-A-A-L-L-K-K-A-A-G-V-E-K-G-T-E-N-P-L-T-H-K-V-G-S-V-T-K-A-Q-V-R-E-I-A-E-I-K-M-E-D-L-S-A-R-D-I-E-A-G-M-K-I-I-E-G-T-A-R-S-M-G-I-T-V-T-D


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-K-A-G-G-H-Q-E-K-V-E-V-G-D-V-I-L-V-N-R-L-D-A-K-K-G-D-T-V-E-F-P-V-S-L-V-V-D-G-D-K-V-T-L-A-A-A-D-L-A-K-V-S-V-K-A-E-V-V-N-D-E-A-K-G-P-K-I-S-I-Q-K-Y-K-N-K-T-G-V-A-R-R-K-G-H-R-Q-K-L-T-I-V-K-I-T-A-I-A


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-Q-I-D-I-I-A-P-G-R-V-K-E-R-Y-L-R-D-A-I-D-E-Y-S-K-R-L-S-R-Y-C-K-L-N-I-I-E-V-A-D-E-K-T-P-D-H-A-S-E-G-V-D-R-Q-I-K-A-R-E-G-E-R-I-A-K-H-L-K-D-G-A-F-V-I-A-L-A-I-N-G-K-Q-L-S-S-E-E-L-A-A-K-I-N-D-L-G-L-R-G-T-S-H-I-Q-L-V-I-G-G-S-I-G-L-D-D-A-I-L-R-R-A-D-F-L-L-S-F-S-K-M-T-F-P-H-Q-L-M-R-V-I-L-L-E-Q-I-Y-R-A-Y-K-I-N-A-G-E-P-Y-H-K


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-T-M-S-D-D-N-E-N-E-Q-P-L-N-L-D-I-P-D-H-L-E-Y-S-E-E-H-A-W-V-D-R-S-V-D-P-A-I-I-G-I-T-E-Y-A-A-D-Q-L-G-E-L-V-F-V-D-L-P-E-P-G-A-R-V-E-A-G-D-E-I-V-E-L-E-S-S-K-A-V-Q-P-L-I-S-P-V-A-G-T-V-K-Y-V-N-R-D-V-A-D-D-P-S-V-V-N-G-D-P-Y-G-E-G-W-L-L-K-V-E-L-D-D-D-E-P-E-L-L-S-A-D-E-Y-A-K-V-V-R


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-P-K-E-T-G-E-K-L-I-V-Q-N-K-K-A-R-H-D-Y-A-I-E-D-K-Y-E-A-G-L-A-L-T-G-T-E-V-K-S-L-R-E-G-R-A-S-L-S-E-A-F-I-S-I-D-R-R-G-E-M-W-L-E-G-A-N-I-P-E-Y-L-N-G-T-W-N-N-H-A-P-K-R-K-R-K-L-L-L-H-R-L-Q-I-T-K-L-A-R-G-I-E-A-K-G-Y-T-I-V-P-L-S-L-Y-F-K-D-G-R-V-K-A-E-I-A-L-A-R-G-K-K-E-F-D-K-R-Q-A-L-R-E-E-Q-D-K-R-E-A-L-R-A-M-R-Y-A-N-M-R-H


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-G-P-S-K-K-H-V-V-L-P-D-P-I-Y-G-S-T-V-V-A-Q-L-I-N-K-I-L-L-D-G-K-K-S-I-A-E-D-I-V-Y-S-A-L-D-M-V-K-E-K-S-D-Q-E-P-V-A-V-L-K-R-A-L-D-N-I-R-P-S-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-K-P-N-R-A-N-T-L-S-L-R-W-L-T-D-F-S-R-A-R-R-E-K-T-M-A-E-R-L-A-N-E-I-L-D-A-S-N-G-L-G-A-S-V-K-R-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-T-V-F-L-P-I-L-V-C-L-C-G-G-V-G-A-S-C-R-Y-L-L-D-V-T-I-K-T-Y-W-Q-R-A-F-P-L-S-T-F-T-I-N-L-I-A-G-F-L-A-G-L-V-A-A-L-A-L-G-G-T-L-D-E-P-W-R-L-V-L-A-T-G-F-L-G-G-F-S-T-F-S-T-A-I-N-E-M-V-T-L-F-R-K-H-R-Y-P-T-A-A-A-Y-L-V-L-S-L-G-V-P-V-V-A-A-A-C-G-F-L-V


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-D-S-Q-S-P-S-A-G-A-R-P-I-T-H-T-T-T-P-P-A-R-K-L-P-D-I-H-L-D-I-V-L-V-V-F-C-G-G-A-I-G-T-A-I-R-Y-A-F-A-Q-I-P-A-A-G-S-F-H-T-G-T-F-V-A-N-M-L-A-C-F-C-Y-A-G-L-T-A-Y-L-A-G-A-S-R-F-G-A-R-S-K-E-L-A-S-R-G-L-G-M-G-V-C-G-G-L-S-T-M-S-T-L-A-L-E-G-F-T-A-I-R-D-G-Q-V-A-A-G-I-A-Y-L-L-V-T-F-A-L-G-L-V-C-A-S-A-G-V-W-A-G-T-H-L-A-G-S-S-N-V-S-A-E-A-S-A-D-T-N-A-A-T-T-S-K-G-G-K-A


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-S-E-T-G-P-S-L-Q-R-P-A-T-R-A-A-R-L-S-A-I-E-Q-A-L-A-T-H-I-I-T-S-Q-S-Q-L-S-K-I-L-I-D-E-G-I-A-V-T-Q-A-T-L-S-R-D-L-D-E-M-H-A-V-K-T-R-L-K-D-G-T-V-A-Y-T-V-G-R-S-V-V-A-S-E-G-E-D-V-G-E-R-G-E-A-Q-M-S-R-V-L-N-G-L-V-T-S-V-A-A-A-G-N-L-V-V-V-H-T-P-S-G-A-A-Q-Y-V-A-S-V-I-D-K-Q-P-I-E-G-V-L-G-T-I-A-G-D-D-T-V-M-V-I-C-T-N-D-D-T-A-V-F-R-S-D-W-L-L-S-L-A-S-K


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-A-S-D-F-W-L-I-A-G-L-G-N-P-G-K-K-Y-E-D-T-R-H-N-M-G-F-M-T-A-D-V-L-A-E-R-W-T-V-N-F-A-D-H-K-G-L-A-M-L-G-K-S-V-M-N-L-D-G-R-T-V-K-F-F-L-A-K-P-L-T-Y-M-N-D-S-G-N-A-V-A-S-I-S-A-Y-Y-Q-I-E-P-D-H-I-V-V-I-H-D-D-M-D-L-E-F-G-R-I-K-V-K-A-G-G-S-A-G-G-H-N-G-I-K-S-I-D-R-S-L-G-T-P-K-Y-A-R-V-R-M-G-V-G-H-S-K-R-G-A-N-A-H-D-N-T-V-N-W-V-L-G-G-F-G-P-D-Q-R-K-Q-L-P-E-F-L-A-D-G-A-D-A-A-E-D-I-I-F-H-G-L-A-K-T-Q-E-K-F-N-G-R


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-V-W-L-G-V-D-L-G-N-A-R-V-G-L-A-L-S-D-P-E-L-T-F-A-H-P-A-G-N-I-H-V-A-G-D-Y-F-F-A-I-D-E-V-L-N-V-I-E-D-E-H-V-D-H-V-I-V-G-L-P-L-Q-M-D-G-T-E-G-K-S-A-K-K-A-R-R-W-A-A-N-L-E-K-R-L-Q-A-E-S-E-D-S-D-S-T-E-Y-Q-I-P-Q-V-S-L-I-D-E-R-L-T-T-V-S-A-H-R-Q-L-F-E-A-H-K-A-S-N-K-H-R-P-V-V-D-Q-Q-S-A-V-V-I-L-Q-T-A-L-D-R-T-R-E-Q


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-V-D-V-T-N-E-T-Q-W-V-I-D-P-K-V-F-S-D-L-G-I-W-V-L-D-Q-M-R-V-S-T-Q-S-D-L-T-I-M-F-V-D-P-D-P-I-A-E-L-H-M-R-W-M-N-L-E-G-P-T-D-V-M-S-F-P-M-D-E-L-R-P-G-D-G-K-T-V-M-E-G-V-L-G-D-I-V-I-C-P-W-V-A-A-Q-Q-A-A-A-A-G-H-S-T-M-Q-E-M-L-L-L-T-I-H-G-I-L-H-L-L-G-Y-D-H-V-T-P-E-Q-E-R-Q-M-F-G-L-Q-R-Q-L-L-L-T-F-F-A-L-R-H-D-A-N-V-Q-A-T-L-P-A-G-T-P-D-A-L-A-L-Y-D-A-A-H-G-A-G-R-D-L-D-S-K


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-K-K-R-V-L-T-N-E-K-A-H-L-R-N-V-A-V-K-S-G-L-K-T-A-I-R-A-T-R-E-A-I-A-A-G-D-K-A-A-A-E-A-A-Y-K-V-A-A-Q-K-L-D-K-A-A-G-A-G-V-I-H-K-N-Q-A-A-N-R-K-S-G-L-A-V-A-I-N-A-L


### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-E-V-T-S-I-Q-N-G-I-I-I-D-H-V-P-A-G-T-S-L-K-V-L-E-Y-L-K-I-D-P-A-K-T-K-L-A-L-I-M-N-A-D-S-K-R-Y-G-S-K-D-I-I-K-I-E-D-D-K-D-I-D-L-D-V-L-G-F-V-A-R-Q-A-T-V-D-V-V-R-G-G-K-I-V-E-K-K-Q-P-N-L-P-E-H-I-V-G-V-I-S-C-V-N-P-R-C-V-T-T-A-E-P-G-I-K-Q-M-F-H-L-V-H-S-E-R-L-E-Y-R-C-D-Y-C-D-E-E-A-K-L


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-A-Q-S-D-I-T-I-D-A-L-S-K-V-G-Q-Q-D-A-E-Y-L-V-S-L-V-R-S-V-P-G-F-P-K-E-G-I-I-F-R-D-F-M-P-V-L-A-D-P-K-G-L-K-I-L-L-K-A-L-E-E-A-L-P-V-S-P-S-E-F-D-S-I-A-G-L-E-S-R-G-F-L-F-G-P-V-M-A-A-H-L-G-K-G-F-I-A-V-R-K-A-G-K-L-P-P-E-T-I-G-E-S-Y-D-L-E-Y-G-T-A-S-V-E-I-E-T-D-A-V-Q-A-G-K-R-V-L-I-V-D-D-L-I-A-T-G-G-T-A-K-A-A-T-D-L-I-E-K-A-G-G-T-V-V-G-F-S-F-V-M-R-L-D-G-L-D-G-L-D-K-L-D-G-K-P-S-S-S-L-I-A-M-P-A


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-E-R-L-Q-S-H-R-D-F-V-T-V-L-K-R-R-R-K-A-G-G-K-D-I-V-V-H-Y-L-V-P-D-D-H-H-D-D-D-D-R-T-V-H-R-R-L-G-L-A-V-S-K-S-V-G-H-A-V-T-R-N-T-V-K-R-R-F-R-V-L-A-R-A-H-E-D-L-L-P-A-H-C-D-I-V-L-R-A-K-P-S-A-A-T-A-S-F-A-S-L-D-Q-Q-I-A-K-A-F-A-T-V-A-H-K-V-A-E-A


### FUNCTION Involved in cell division ### SEQUENCE -M-E-Q-V-Q-A-A-L-N-A-T-A-D-K-A-T-L-T-P-Q-M-Q-R-M-M-N-R-Q-A-E-N-T-K-R-V-E-E-T-I-K-G-T-K-S-N-P-R-W-F-V-P-L-F-C-A-L-M-I-I-G-L-I-W-C-V-V-Y-Y-L-S-P-S-G-S-W-P-I-P-N-I-G-A-W-N-L-G-I-G-F-A-L-I-M-I-G-F-L-M-T-M-G-W-R


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-M-W-M-I-C-L-F-G-G-L-G-A-M-A-R-Y-V-L-D-V-S-I-Q-R-G-W-N-R-E-N-R-R-T-N-R-N-F-P-L-S-T-L-V-I-N-G-V-A-S-L-C-A-G-I-A-M-M-S-Y-Y-S-Q-S-V-D-M-D-T-V-M-M-F-V-V-G-F-L-G-G-F-S-T-F-S-T-A-L-N-E-V-V-S-L-I-R-Q-R-R-F-T-L-A-L-G-Y-G-I-A-T-V-A-V-P-L-I-C-V-A-A-G-F-G-I-A-L-L-A-N-P-A


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-A-L-A-Y-D-G-A-I-Q-R-L-I-D-A-F-G-R-L-P-G-I-G-P-K-G-A-Q-R-I-A-F-Y-M-L-S-A-P-E-D-E-A-R-D-L-A-E-A-I-E-E-V-K-A-K-I-R-F-C-D-I-C-G-N-V-C-E-S-S-P-C-P-V-C-A-D-P-R-R-D-R-S-V-I-C-V-V-E-E-P-K-D-V-M-S-I-E-R-T-R-E-Y-H-G-L-Y-H-V-L-G-G-A-I-N-P-M-A-N-V-G-P-A-D-L-R-I-P-G-L-L-K-R-L-E-G-D-E-V-K-E-V-I-M-A-L-D-P-N-I-E-G-E-A-T-T-S-Y-L-T-Q-L-L-R-P-V-G-V-K-V-T-R-L-A-S-G-L-P-V-G-S-D-L-E-Y-A-D-E-I-T-L-G-R-A-L-A-G-R-R-E-A


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-M-S-A-H-K-Y-E-L-M-F-I-A-D-P-E-L-D-E-R-G-L-K-K-L-T-E-Q-Y-L-E-L-V-T-K-E-G-G-S-F-D-E-P-D-Y-W-G-R-R-K-L-A-Y-E-I-A-G-K-T-E-G-N-Y-V-V-V-K-Y-T-A-E-P-A-T-S-D-E-L-D-R-V-L-N-L-N-E-S-V-I-R-T-K-I-L-R-K-G


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-S-R-K-R-P-Q-P-P-V-K-P-F-K-K-K-P-N-P-L-K-A-A-K-V-T-E-I-D-Y-K-D-V-A-L-L-R-K-F-I-S-D-R-G-K-I-R-S-R-R-I-T-G-V-T-V-Q-E-Q-R-E-L-S-K-A-I-K-N-A-R-E-M-A-L-L-P-Y-A-T-S-G-R


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-A-E-T-K-V-I-L-T-K-T-V-S-N-L-G-H-S-G-D-V-V-D-V-K-S-G-Y-A-R-N-Y-L-F-P-Q-G-L-A-F-A-W-T-K-G-A-E-A-Q-I-V-A-M-K-R-A-R-L-A-K-A-V-A-T-R-E-D-A-V-A-A-K-A-A-I-E-G-T-T-V-E-I-A-A-K-V-S-E-S-G-K-L-F-G-G-I-S-N-E-A-I-A-V-A-L-S-D-K-A-A-V-N-P-K-A-I-E-V-E-T-I-K-T-T-G-D-F-P-A-K-V-A-L-H-P-E-I-T-A-S-F-F-V-K-V-V-A-E


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-I-S-I-I-I-Q-I-L-L-I-S-V-S-V-A-M-D-A-F-A-V-S-I-G-K-G-L-T-V-S-R-V-R-V-Q-D-A-V-K-S-T-L-W-F-G-G-F-Q-M-L-F-P-I-L-G-Y-F-A-A-S-T-F-S-K-Y-V-T-Q-F-D-H-W-I-I-F-A-L-L-V-F-I-G-G-N-M-V-H-E-A-F-E-E-D-E-E-N-S-K-E-T-A-Q-F-D-W-K-H-M-L-P-L-A-V-A-C-S-I-D-A-F-A-V-G-V-S-L-A-F-M-F-T-K-A-H-M-A-F-A-I-L-S-I-G-V-V-T-G-L-F-S-A-A-G-L-H-I-G-R-A-F-G-S-R-W-Q-K-P-A-Q-I-A-G-G-V-V-L-I-L-L-G-I-K-V-L-L-E-H-L-G-V-I-A-F


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-M-T-Q-A-A-S-G-I-D-L-F-I-P-E-V-Y-D-I-V-W-S-L-I-I-L-V-I-V-A-V-F-F-Y-K-F-F-M-P-K-F-N-A-I-F-D-E-R-A-A-K-I-Q-G-N-I-A-K-A-E-Q-A-R-K-D-A-D-E-A-K-A-K-Y-E-A-Q-L-S-T-A-R-V-D-A-A-K-I-R-D-D-A-R-A-E-A-S-H-I-I-A-D-A-R-S-R-A-E-S-D-A-A-Q-I-T-A-S-A-Q-R-S-I-E-S-Q-H-Q-Q-A-I-V-S-L-K-G-E-V-G-A-L-A-T-A-L-A-G-K-I-L-G-A-K-L-E-D-N-D-V-Q-S-S-M-I-D-S-M-I-D-D-L-G-A-K-K


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-G-F-M-K-N-A-M-S-Y-L-G-M-S-D-V-V-D-D-E-D-D-Y-I-E-E-D-E-E-Q-K-P-A-S-K-S-A-F-D-S-D-H-T-V-T-P-L-A-S-T-T-A-P-A-A-S-S-T-T-K-P-F-P-G-G-R-V-N-R-I-T-T-I-H-P-K-S-Y-E-D-A-Q-L-V-G-R-A-L-R-D-G-V-P-V-V-L-N-L-T-G-V-A-E-A-V-A-Y-R-I-V-D-F-S-A-G-V-V-F-G-V-R-G-S-L-E-R-V-T-P-R-V-F-L-L-S-P-A-Q-V-N-I-K-V-E-E-P-T-K-P-A-S-A-H-D-L-F-A-D