### FUNCTION Involved in the transport of copper ### SEQUENCE -M-R-G-M-G-D-D-G-M-G-P-M-A-M-A-P-P-R-S-G-H-A-T-A-A-A-P-P-P-P-Q-H-K-M-A-M-M-M-H-M-T-F-F-W-S-D-R-A-V-V-L-I-R-G-W-P-G-E-R-G-A-G-M-Y-A-L-C-L-L-F-V-L-A-L-A-A-L-T-E-G-L-S-V-L-S-R-R-L-A-R-R-G-G-G-A-A-S-S-D-G-G-R-P-A-P-A-P-A-S-S-A-A-L-L-T-A-V-H-A-A-R-M-G-M-A-Y-L-V-M-L-A-V-M-S-F-N-V-G-V-L-L-A-A-V-A-G-H-A-L-G-F-L-L-A-R-S-R-V-R-P-A-A-R-D-G-G-G-G-V-A-C-E-H-G-G-L-P-P-A-D-G-S-K-T


### FUNCTION Regulates membrane-cell wall junctions and localized cell wall deposition Required for establishment of the Casparian strip membrane domain ### SEQUENCE -M-E-H-G-E-I-S-S-K-A-P-L-V-A-P-V-A-A-G-V-N-R-A-V-A-V-V-D-T-F-L-R-F-I-A-I-I-G-T-I-G-S-A-I-A-M-G-T-T-N-E-T-L-P-F-F-T-Q-F-I-Q-F-E-A-K-Y-S-D-L-P-S-F-T-F-F-V-A-A-N-A-V-V-C-T-Y-L-V-L-S-I-P-L-S-I-V-H-I-L-R-P-R-A-R-Y-S-R-L-F-L-V-F-F-D-T-A-M-L-A-L-L-T-A-G-A-S-A-A-A-A-I-V-Y-L-A-H-K-G-N-V-R-A-N-W-F-S-I-C-Q-Q-F-D-S-F-C-E-R-I-S-G-S-L-I-G-S-F-A-A-M-V-L-L-V-V-L-I-T-L-S-A-F-A-L-A-R-R-H


### FUNCTION Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca complex are a number of protein kinases and phosphatases ### SEQUENCE -M-A-D-Q-L-T-D-D-Q-I-S-E-F-K-E-A-F-S-L-F-D-K-D-G-D-G-C-I-T-T-K-E-L-G-T-V-M-R-S-L-G-Q-N-P-T-E-A-E-L-Q-D-M-I-N-E-V-D-A-D-G-N-G-T-I-D-F-P-E-F-L-N-L-M-A-R-K-M-K-D-T-D-S-E-E-E-L-K-E-A-F-R-V-F-D-K-D-Q-N-G-F-I-S-A-A-E-L-R-H-V-M-T-N-L-G-E-K-L-T-D-E-E-V-D-E-M-I-R-E-A-D-V-D-G-D-G-Q-I-N-Y-E-E-F-V-K-V-M-M-A-K


### FUNCTION Acts in maintaining the cortical microtubules organization essential for anisotropic cell growth ### SEQUENCE -M-S-R-G-G-S-A-G-G-G-Q-S-S-L-G-Y-L-F-G-G-N-E-A-P-K-P-A-A-K-P-A-P-A-A-A-P-A-P-A-P-A-P-A-P-A-A-A-V-A-A-P-A-E-K-P-S-P-A-K-A-D-A-T-K-Q-I-P-A-G-I-Q-G-S-R-S-N-N-N-Y-H-R-A-D-G-Q-N-T-G-N-F-L-T-D-R-P-S-T-K-V-H-A-A-P-G-G-G-S-S-L-G-Y-L-F-G-G-N


### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-A-Q-E-S-W-K-N-E-S-E-E-T-V-H-T-P-E-A-P-I-L-C-V-N-N-C-G-F-F-G-S-S-M-T-N-N-M-C-S-K-C-Y-R-D-F-V-K-V-T-T-M-A-A-P-V-V-E-K-K-A-F-T-P-A-S-S-S-K-T-P-L-E-P-A-K-P-D-E-V-P-A-A-A-V-E-D-K-Q-A-A-Q-E-P-P-K-P-P-S-N-R-C-L-S-C-R-K-K-V-G-L-T-G-F-Q-C-R-C-G-G-T-F-C-S-T-H-R-Y-T-E-A-H-D-C-T-F-D-Y-K-K-A-G-R-D-Q-I-A-K-Q-N-P-V-V-I-A-E-K-I-N-K-I


### FUNCTION Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans Host outer membrane disruption is possibly due to local fusion between the inner and outer membrane performed by the spanin complex ### SEQUENCE -M-P-R-T-I-V-A-I-L-V-L-A-V-V-A-L-G-A-S-Y-G-F-V-Q-S-Y-R-A-L-G-I-A-Q-G-E-I-K-R-Q-T-A-R-A-E-A-L-E-V-R-Y-A-T-L-Q-R-H-V-K-E-V-A-A-R-T-N-T-Q-R-Q-E-V-D-R-A-L-D-Q-N-R-P-W-A-D-R-P-V-P-A-A-V-V-D-S-L-C-N-R-P-G-A-R-C-A-V-R-T-P-T-D


### FUNCTION Capsid decoration protein which helps to stabilize the capsid against extremes of pH and temperature Once maturation and expansion of the capsid has occured, trimers of soc attach the interfaces between the hexamer of the major capsid protein Acts as a 'glue' between neighboring hexameric capsomers Dispensable for the head morphogenesis and phage infection ### SEQUENCE -M-G-G-Y-V-N-I-K-T-F-T-H-P-A-G-E-G-K-E-V-K-G-M-E-V-S-V-P-F-E-I-Y-S-N-E-H-R-I-A-D-A-H-Y-Q-T-F-P-S-E-K-A-A-Y-T-T-V-V-T-D-A-A-D-W-R-T-K-N-A-A-M-F-T-P-T-P-V-S-G


### FUNCTION Forms the collar, into which the side tail fiber protein pb1 is anchored ### SEQUENCE -M-S-T-E-N-R-V-I-D-L-V-V-D-E-N-V-P-Y-G-L-L-M-Q-F-M-D-V-D-D-S-V-Y-P-S-T-S-K-P-V-D-L-T-D-F-S-L-R-G-S-I-K-S-S-L-E-D-G-A-E-T-V-A-S-F-T-T-A-I-V-D-A-A-Q-G-V-A-S-I-S-L-P-V-S-A-V-T-T-I-A-S-K-A-S-K-E-R-D-R-Y-N-P-R-Q-R-L-A-G-Y-Y-D-V-I-I-T-R-T-A-V-G-S-A-A-S-S-F-R-I-M-E-G-K-V-Y-I-S-D-G-V-T-Q


### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-I-K-Q-L-I-R-N-T-R-Q-P-I-R-N-V-T-K-S-P-A-L-R-G-C-P-Q-R-R-G-T-C-T-R-V-Y-T-I-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-I-T-A-Y-I-P-G-I-G-H-N-S-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-A-V-G-V-K-D-R-Q-Q-G-R-S-K-Y-G-V-K-K-P-K


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-V-P-T-A-F-L-L-I-I-Y-V-K-T-E-S-Q-N-K-K


### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-D-G-I-K-Y-A-V-F-T-E-K-S-I-R-L-L-G-N-N-Q-Y-T-S-N-V-E-S-G-S-T-R-T-E-I-K-H-W-V-E-L-F-F-G-V-K-V-I-A-M-N-S-H-R-L-P-G-K-G-R-R-M-G-H-T-M-H-Y-R-R-M-I-I-T-L-Q-P-G-Y-S-I-P-P-L-I-E-K-R-T


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-L-K-K-N-P-F-V-A-N-H-L-L-A-K-I-E-K-L-N-M-R-E-E-K-E-T-I-V-T-W-S-R-A-S-T-I-I-P-T-M-I-G-H-T-I-A-I-H-N-G-K-E-H-L-P-I-F-I-T-D-R-M-V-G-H-K-L-G-E-F-A-P-T-L-T-F-R-G-H-A-R-T-D-T-R-S-R-R


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-S-K-K-K-Q-K-M-K-R-S-S-S-T-Q-V-Q-A-L-A-Q-H-I-S-M-S-A-H-K-A-R-R-V-V-D-Q-I-R-G-R-S-Y-A-E-T-L-M-L-L-E-L-M-P-Y-R-A-S-Y-P-I-F-K-L-V-Y-S-A-A-A-N-A-S-H-N-K-S-F-N-E-A-D-S-F-I-S-K-A-E-V-N-G-G-T-I-V-K-K-F-K-P-R-A-K-G-R-S-Y-P-I-K-R-P-T-C-H-I-T-I-V-L-K-D-R-S-K-K-K-T-D-Q-D-M-F-L-G-T-K-N-V


### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-P-Q-T-H-L-N-V-A-D-N-S-G-A-R-E-L-M-C-I-R-I-I-G-A-S-N-R-R-Y-A-H-I-G-D-V-I-V-A-V-I-K-E-A-V-P-N-M-P-L-E-R-S-E-V-I-R-A-V-I-V-R-T-C-K-E-L-K-R-D-N-G-M-I-I-R-Y-D-D-N-A-A-V-V-I-D-Q-E-G-N-P-K-G-T-R-V-F-G-A-I-A-R-E-L-R-K-L-N-F-T-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-G-R-D-T-I-A-D-I-L-T-S-I-R-N-A-N-M-D-K-K-G-T-V-R-I-A-S-T-N-I-T-E-N-I-V-K-I-L-L-R-E-G-F-I-E-N-V-R-K-H-Q-E-N-N-K-Y-F-L-V-S-T-L-Q-H-R-R-N-R-K-G-R-Y-R-T-I-L-K-R-I-S-R-P-G-L-R-I-Y-S-N-Y-Q-R-I-P-R-I-L-G-G-M-G-I-V-I-L-S-T-S-Q-G-I-M-T-D-R-E-A-R-L-E-G-I-G-G-E-I-L-C-Y-I-W


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-E-Q-K-L-I-H-E-G-L-I-T-E-S-L-P-N-G-M-F-R-V-R-L-D-N-E-D-L-I-L-G-Y-V-S-G-R-I-R-R-S-F-I-R-I-L-P-G-D-R-V-K-I-E-V-S-S-Y-D-S-T-R-G-R-I-I-Y-R-L-R-N-K-D-S-N-D


### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-G-V-T-K-K-P-D-L-N-D-P-V-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-S-P-V-V-I-L-G-T-I-A-C-N-V-G-L-A-V-L-E-P-S-M-I-G-E-P-A-D-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-F-P-V-F-Q-I-L-R-T-V-P-N-K-L-L-G-V-L-L-M-V-L-V-P-T-G-L-L-T-V-P-F-L-E-N-V-N-K-F-Q-N-P-F-R-R-P-V-A-T-T-V-F-L-I-G-T-A-V-A-L-W-L-G-I-G-A-T-L-P-I-D-K-S-L-T-L-G-L-F-Q-V-D-L-T-V-K


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-T-K-K-M-K


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-I-R-R-G-Y-I-A-R-R-R-R-T-K-I-R-L-F-A-S-T-F-R-G-A-H-S-R-L-T-R-T-I-T-Q-Q-K-M-R-A-L-V-S-T-Q-R-D-R-G-R-R-K-R-D-F-R-R-L-W-I-T-R-I-N-A-V-T-R-E-N-R-V-S-Y-S-Y-S-R-L-I-H-D-L-Y-K-K-R-L-L-L-N-R-K-I-L-A-Q-I-A-I-S-N-R-N-C-L-D-T-I-S-N-E-I-L-K


### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-R-D-I-K-T-Y-L-S-T-A-P-V-L-A-T-L-W-F-G-S-L-A-G-L-L-I-E-I-N-R-L-F-P-D-A-L-T-F-P-F-F-S-F


### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex ### SEQUENCE -M-P-T-I-T-S-Y-F-G-F-L-L-A-A-S-T-I-T-P-A-L-L-I-G-L-N-K-I-R-L-I


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-D-T-T-G-R-I-P-L-W-L-I-G-T-V-T-G-I-P-V-I-G-S-I-G-I-F-F-Y-G-S-Y-S-G-L-G-S-S-L


### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-N-W-R-S-E-R-I-W-I-E-L-I-T-G-S-R-K-T-S-N-F-C-W-A-C-I-L-F-L-G-S-L-G-F-L-L-V-G-T-S-S-Y-L-G-R-N-L-I-S-L-F-P-S-Q-Q-I-I-F-F-P-Q-G-I-V-M-S-F-Y-G-I-A-G-L-F-I-S-S-Y-L-W-C-T-I-S-W-N-V-G-S-G-Y-D-R-F-D-R-K-E-G-I-V-C-I-F-R-W-G-F-P-G-I-N-R-R-I-F-L-R-F-L-M-R-D-I-Q-S-I-R-M-E-V-K-G-G-L-Y-S-R-R-V-L-Y-M-E-I-R-G-Q-G-A-I-P-L-T-R-T-D-E-N-F-T-P-R-E-I-E-Q-K-A-A-E-L-A-Y-F-L-R-V-P-I-E-L-K


### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-T-D-L-N-L-P-S-I-F-V-P-L-V-G-L-M-F-P-A-I-A-M-A-S-L-S-L-H-I-Q-K-N-K-I-I


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-T-L-N-L-C-V-L-T-P-N-R-I-I-W-D-S-E-V-K-E-I-I-L-S-T-N-S-G-Q-I-G-V-L-P-N-H-A-P-I-A-T-A-V-D-I-G-I-L-R-I-R-L-N-G-Q-W-L-M-M-A-V-M-G-G-F-A-R-I-G-N-N-E-I-T-I-L-V-N-D-A-E-K-G-S-D-I-D-P-Q-E-A-Q-R-T-L-E-I-A-E-A-N-L-S-K-A-E-G-K-R-Q-V-I-E-A-N-L-A-L-R-R-A-R-T-R-V-E-A-I-N-V-I


### FUNCTION Essential for the assembly of the photosystem I  complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-R-I-N-G-N-F-I-D-K-T-S-S-I-V-A-N-I-L-L-R-I-I-P-T-T-S-G-E-K-E-A-F-T-Y-Y-R-D-G-M-S-A-Q-S-E-G-N-Y-A-E-A-L-Q-N-Y-Y-E-A-T-R-L-E-I-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-E-H-T-K-A-L-E-Y-Y-F-R-A-I-E-R-N-P-F-L-P-Q-A-F-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-R-Q-G-D-S-E-I-A-E-A-W-S-D-Q-A-A-E-Y-W-K-Q-A-I-A-L-T-P-G-N-Y-I-E-A-H-N-W-L-K-I-A-R-R-F-E


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-R-K-G-L-I-Q-R-E-R-K-R-Q-K-L-E-Q-K-Y-H-L-I-R-R-S-P-K-K-E-I-G-K-V-S-S-L-S-D-K-W-K-I-H-G-K-L-Q-S-P-P-R-N-S-A-P-T-R-L-H-R-R-C-F-L-T-G-R-P-R-A-N-Y-R-D-F-G-L-S-G-H-I-L-R-E-K-V-H-A-C-L-L-P-G-A-T-R-S-S-W


### FUNCTION Controls the interaction of photosystem II  cores with the light-harvesting antenna ### SEQUENCE -M-I-I-A-F-Q-L-A-V-F-A-L-I-A-T-S-S-I-L-L-I-S-V-P-V-V-F-A-S-P-D-G-W-S-N-N-K-N-V-V-F-S-G-T-S-L-W-I-G-L-V-F-L-V-A-I-L-N-S-L-I-S


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-N-V-T-D-S-F-V-S-L-G-H-W-P-F-A-G-S-F-G-F-N-T-D-I-L-A-T-N-L-I-N-L-S-V-V-L-G-V-L-I-F-F-G-K-G-V-L-S-D-L-L-D-N-R-K-Q-R-I-W-S-T-I-R-N-S-D-E-L-R-E-V-A-I-E-Q-L-E-K-A-R-A-R-L-R-K-V-E-R-E-A-D-E-F-R-V-N-G-Y-S-E-I-E-R-E-K-W-N-L-I-N-A-T-Y-E-N-L-E-R-L-E-N-Y-K-N-E-T-I-H-F-E-Q-Q-R-A-I-N-Q-V-R-Q-R-V-F-Q-Q-A-L-Q-G-A-L-G-T-L-N-S-R-S-N-S-E-L-H-L-R-T-I-S-A-N-I-G-M-L-G-A-M-K-E-I-T-D


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-N-I-F-S-L-I-C-L-N-S-A-L-H-S-S-S-F-F-F-A-K-L-P-E-A-Y-A-F-F-N-P-I-V-D-V-M-P-V-I-P-V-L-F-F-L-L-A-L-V-W-Q-A-A-V-S-F-R


### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-C-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-K-E-L-R-D-P-F-E-E-H-E-D


### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-I-A-I-F-I-S-C-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-K-E-L-R-D-P-F-E-E-H-E-D


### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-L-T-F-N-Q-L-I-K-N-S-R-K-K-K-N-K-F-K-N-S-I-L-N-R-C-P-Q-K-K-G-I-C-L-K-V-F-T-K-S-P-K-K-P-N-S-A-L-R-K-V-V-K-I-R-L-S-N-N-K-E-I-I-A-Y-I-P-G-E-G-Y-A-I-Q-E-H-N-Y-A-L-I-K-G-G-K-V-Q-D-L-P-G-I-R-Y-K-I-I-R-G-A-L-N-V-S-G-V-K-N-R-K-S-S-R-S-K-Y-G-T-K-K


### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-T-Q-I-N-T-Y-F-N-I-A-D-N-S-G-V-K-K-I-L-C-I-Q-N-L-T-K-K-T-K-K-I-E-I-G-D-L-I-V-G-V-I-K-K-I-N-N-T-S-K-L-I-Y-S-N-I-V-Y-G-I-V-I-R-L-K-K-N-I-N-L-Y-K-K-Y-N-I-S-F-N-D-N-S-A-V-L-V-D-K-N-L-N-P-I-G-S-R-I-F-G-T-I-P-K-F-L-K-K-K-N-Y-L-K-L-Y-S-L-T-V-D-F-I


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-L-R-Y-L-G-P-K-L-K-K-L-K-R-L-N-I-H-M-Q-P-E-F-S-T-K-Y-F-I-L-N-T-N-K-Y-N-N-K-M-I-L-S-F-Y-L-L-E-L-F-E-K-Q-K-L-K-F-T-F-S-L-S-E-K-I-I-K-K-Y-I-L-F-M-H-K-Y-N-Y-K-K-F-N-L-I-N-I-I-E-I-R-L-D-N-T-I-F-N-L-G-Y-S-I-T-I-A-Q-A-K-Q-L-I-I-H-G-Y-F-F-V-N-F-K-L-I-K-I-P-S-F-L-L-K-K-G-D-I-I-T-L-S-P-K-S-Y-Y-I-F-K-L-C-K-K-N-L-Y-K-K-Y-I-K-N-S-N-I-Y-D-T-I-Y-I-C-K-N-T-L-I-S-I-I-Y-S-I-L-N-I-Y-N-N-N-N-Y-N-N-I-L-I-M-K-Y-Y-S-Y


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-I-Q-T-K-K-I-K


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-S-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-I-Q-T-K-K-M-K


### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-I-A-I-F-I-S-G-L-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-Q-P-S-Q-Q-L-R-D-P-F-E-E-H-G-D


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-V-P-T-A-F-L-L-I-I-Y-V-K-T-E-S-Q-N-K-K


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-V-P-T-A-F-L-L-I-I-Y-V-K-T-E-S-Q-N-K-K-N


### FUNCTION Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains ### SEQUENCE -M-M-E-V-E-S-S-Y-S-D-F-I-S-C-D-R-S-G-R-R-N-A-V-P-D-I-Q-G-D-S-E-A-V-S-V-R-K-L-A-G-D-M-G-E-L-A-L-E-G-A-E-G-Q-A-E-V-G-T-S-D-K-E-A-S-S-Q-P-E-S-S-D-G-T-T-S-S


### FUNCTION Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains ### SEQUENCE -M-M-E-V-E-S-S-Y-S-D-F-I-S-C-D-R-T-G-R-R-N-A-V-P-D-I-Q-G-D-S-E-A-V-S-V-R-K-L-A-G-D-M-G-E-L-A-L-E-G-A-E-G-Q-A-E-G-G-T-P-D-K-E-A-S-N-Q-P-Q-S-S-D-G-T-T-S-S


### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-S-S-A-L-A-K-P-Q-M-R-G-L-L-A-R-R-L-R-I-H-I-V-G-A-F-V-V-S-L-G-V-A-A-F-Y-K-Y-A-V-A-E-P-R-K-K-A-Y-A-D-F-Y-R-N-Y-D-S-V-K-Y-F-E-E-M-R-K-A-G-V-F-Q-S-V-K


### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-S-E-V-L-A-K-P-Q-M-R-G-L-L-A-R-R-L-R-I-H-M-V-G-A-F-L-I-S-L-G-V-A-A-L-Y-K-F-G-V-A-E-P-R-K-K-A-Y-A-D-F-Y-K-N-Y-S-P-E-K-D-F-E-E-M-K-K-A-G-V-F-R-S-I-K


### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-S-E-V-L-V-K-P-Q-M-R-G-L-L-A-R-R-L-R-I-H-M-V-G-A-F-L-V-S-L-G-V-A-A-L-Y-K-F-G-V-A-E-P-R-K-K-A-Y-A-D-F-Y-K-N-Y-S-A-E-K-D-F-E-E-M-K-K-A-G-L-F-R-S-I-K


### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-P-E-V-L-P-K-P-Q-M-R-G-L-L-A-K-R-L-R-F-H-M-V-T-A-F-V-L-S-L-G-V-A-A-L-Y-K-F-R-V-A-D-K-R-K-K-A-Y-A-D-F-Y-R-N-Y-D-A-M-K-D-F-E-E-M-R-K-A-G-I-F-Q-S-V-K


### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-P-E-V-L-P-K-P-Q-M-R-G-L-L-A-R-R-L-R-F-H-M-V-T-G-F-V-L-S-L-G-V-A-A-L-Y-K-V-G-V-A-D-K-R-K-K-A-Y-A-D-F-Y-R-N-Y-D-A-M-K-D-F-E-E-M-R-K-A-G-I-F-Q-S-V-K


### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-A-P-E-V-L-P-K-P-R-M-R-G-L-L-A-R-R-L-R-N-H-M-A-V-A-F-V-L-S-L-G-V-A-A-L-Y-K-F-R-V-A-D-R-R-K-K-A-Y-A-D-F-Y-R-N-Y-D-V-M-K-D-F-E-E-M-R-K-A-G-I-F-Q-S-V-K


### FUNCTION Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix ### SEQUENCE -M-S-S-G-A-L-T-K-P-Q-M-R-G-L-L-A-K-R-L-R-F-H-I-V-G-A-F-A-V-S-L-G-V-A-A-F-Y-K-F-A-V-A-E-P-R-K-K-A-Y-A-D-F-Y-R-N-Y-D-S-M-K-D-F-E-E-M-R-K-A-G-I-F-Q-S-A-K


### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels  and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-M-I-T-A-C-L-V-L-F-G-T-V-W-A-K-E-G-Y-L-V-N-K-S-T-G-C-K-Y-G-C-F-W-L-G-K-N-E-N-C-D-M-E-C-K-A-K-N-Q-G-G-S-Y-G-Y-C-Y-S-F-A-C-W-C-E-G-L-P-D-S-T-P-T-Y-P-L-P-N-K-S-C-S-K-K


### FUNCTION Nontoxic peptide ### SEQUENCE -M-K-N-Y-S-K-N-A-T-H-L-I-T-V-L-L-F-S-F-V-V-I-L-L-I-I-P-S-K-C-E-A-V-S-N-N-M-Q-P-L-E-A-R-S-A-D-L-V-Q-E-P-R-Y-I-I-N-V-P-P-R-C-P-P-G-S-K-F-I-K-N-R-C-R-V-I-V-P


### FUNCTION Nontoxic peptide ### SEQUENCE -M-K-N-Y-S-K-N-A-T-Y-L-I-T-V-L-L-F-S-F-V-A-M-L-L-I-I-P-S-K-C-E-A-V-S-N-D-M-Q-P-L-E-A-R-S-A-D-L-V-P-E-P-R-Y-I-I-D-V-P-P-R-C-P-P-G-S-K-F-I-K-N-R-C-R-V-I-V-P


### FUNCTION Nontoxic peptide ### SEQUENCE -M-K-N-Y-S-K-N-A-T-H-L-I-T-V-L-L-F-S-F-V-V-I-L-L-I-I-P-S-K-C-E-A-V-S-N-D-M-Q-P-L-E-A-R-S-A-D-L-I-P-E-P-R-Y-I-I-D-V-P-P-R-C-P-P-G-S-K-F-I-K-N-R-C-R-V-I-V-P


### FUNCTION Nontoxic peptide ### SEQUENCE -M-K-N-Y-S-K-N-A-T-Y-L-I-T-V-L-L-F-S-F-V-T-M-L-L-I-I-P-S-K-C-E-A-V-S-N-D-M-Q-P-L-E-A-R-T-A-D-L-V-Q-Q-P-R-Y-I-I-D-V-P-P-R-C-P-P-G-S-K-F-V-H-K-R-C-R-V-I-V-P


### FUNCTION Nontoxic peptide ### SEQUENCE -M-K-N-Y-S-K-N-A-T-Y-L-I-T-V-L-L-F-S-F-V-A-M-L-L-I-I-P-S-K-C-E-A-V-S-N-D-M-Q-P-L-E-A-R-T-A-D-L-V-Q-Q-P-R-Y-I-I-D-V-P-P-R-C-P-P-G-S-K-F-V-H-K-R-C-R-V-I-V-P


### FUNCTION Functions downstream of migratory protein mig-13 and may play a role in the control of Q neuroblast migration during larval development ### SEQUENCE -M-M-M-T-M-A-A-D-Y-G-S-S-E-G-H-Y-D-T-P-W-E-F-L-A-R-P-N-S-V-R-F-S-T-A-D-V-R-L-S-T-S-A-A-G-D-A-K-V-S-P-H-G-S-P-S-L-C-S-S-S-S-F-V-N-Q-L-V-Q-I-G-N-S-A-V-D-A-R-R-K-V-P-R-D-E-S-K-R-R-R-P-S-D-S-E-I-Y-M-E-Q-N-M-N-R-V-E-A-E-K-R-L-E-N-R-N-L-G-D-Y-L-L-R-S-R-G-E-G-S-A-A-L-S-L-R-A-T-K-G-V-V-H-I-K-I-E-W-N-G-E-K-W-V-I-G-E-G-P-L-F-R-S-I-S-S-A-I-S-F-Y-R-R-H-P-L-P-I-R-G-A-D-H-L-V-L-K-N-Q-L-K-P-V


### FUNCTION Involved in mitochondria homeostasis ### SEQUENCE -M-V-I-I-L-F-I-R-R-R-L-A-T-N-P-L-S-T-Q-M-C-I-A-G-T-I-S-G-S-G-D-C-L-A-Q-Y-L-S-H-N-Q-E-W-D-R-W-R-T-A-R-F-S-F-L-S-S-C-F-M-A-P-S-L-F-I-W-F-R-L-L-E-K-V-K-G-N-N-K-S-L-L-L-V-K-K-L-C-I-D-Q-L-C-F-S-P-C-F-N-A-A-I-L-F-N-L-R-L-L-Q-H-Q-S-A-E-K-S-W-D-L-L-K-E-D-W-F-N-I-Y-A-T-S-L-K-V-W-P-F-V-Q-V-V-N-L-C-F-V-P-L-N-Y-R-V-I-L-N-Q-V-V-A-F-F-W-N-C-Y-L-S-Y-I-T-Q-K-P-I-D-H-I-E-Q-F-Y


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -M-K-L-C-L-T-F-L-L-V-L-M-I-L-A-S-V-T-G-E-K-L-S-E-Q-T-L-R-R-A-A-R-K-N-K-G-P-R-C-W-V-G-R-V-H-C-T-Y-H-K-D-C-C-P-S-V-C-C-F-K-G-R-C-K-P-Q-S-W-G-C-W-S-G-P-T


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-P-S-F-C-K-A-N-G-K-P-C-S-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-A-P-S-T-N-W-I-L-P-G-C-S-T-S-S-F-F-K-I


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-P-S-F-C-K-A-D-E-K-P-C-E-Y-H-S-D-C-C-N-C-C-L-S-G-I-C-A-P-S-T-N-W-I-L-P-G-C-S-T-S-S-F-F-K-I


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-A-V-P-C-G-K-D-G-R-Q-C-R-N-H-A-D-C-C-N-C-C-P-F-G-T-C-A-P-S-T-N-R-I-L-P-G-C-S-T-G-M-F-L-T-R


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-A-V-P-C-G-K-D-G-R-Q-C-R-N-H-A-D-C-C-N-C-C-P-I-G-T-C-A-P-S-T-N-W-I-L-P-G-C-S-T-G-Q-F-M-T-R


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-A-V-P-C-G-K-D-G-R-Q-C-R-N-H-A-D-C-C-N-C-C-P-I-G-T-C-A-P-S-T-N-W-I-L-P-G-C-S-T-G-P-F-M-T-R


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-S-C-G-K-D-G-R-A-C-D-Y-H-A-D-C-C-N-C-C-L-G-G-I-C-K-P-S-T-S-W-I-G-C-S-T-N-V-F-L-T-R


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-G-R-K-C-G-Y-H-T-H-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-L-I-G-C-S-T-S-S-F-T


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-G-R-K-C-G-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-W-T-G-C-S-T-S-T-F-N


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-G-R-K-C-G-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-W-T-G-C-S-T-S-T-F-L-L-T-R


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-R-R-K-C-G-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-W-T-G-C-S-T-S-T-F-L-L-T-R


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-G-R-K-C-G-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-W-T-G-C-S-T-S-T-V-Q-L-T-R


### FUNCTION Iota-conotoxins bind to voltage-gated sodium channels ### SEQUENCE -G-H-V-P-C-G-K-D-G-R-K-C-G-Y-H-A-D-C-C-N-C-C-L-S-G-I-C-K-P-S-T-S-W-T-G-C-S-T-S-T-F-D


### FUNCTION Necessary for protein translocation in the endoplasmic reticulum ### SEQUENCE -M-D-Q-V-T-K-F-I-E-P-G-R-Q-F-A-K-D-S-I-R-L-V-K-R-C-T-K-P-D-R-K-E-F-Q-K-I-A-V-A-T-A-I-G-F-C-I-M-G-F-I-G-F-F-V-K-L-I-H-I-P-I-N-N-I-I-V-G-S


### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels  and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -T-V-S-A-K-E-G-Y-L-V-K-K-S-N-G-C-K-Y-E-C-F-K-L-G-E-N-E-H-C-D-T-E-C-K-A-P-N-Q-G-G-S-Y-G-Y-C-D-T-F-E-C-W-C-E-G-L-P-E-S-T-P-T-W-P-L-P-N-K-S-C-G-K-K


### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels  and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-M-I-I-G-C-L-V-L-I-G-T-V-W-T-K-E-G-Y-L-V-N-M-K-T-G-C-K-Y-G-C-Y-E-L-G-D-N-G-Y-C-D-R-K-C-K-A-E-S-G-N-Y-G-Y-C-Y-T-V-G-C-W-C-E-G-L-P-N-S-K-P-T-W-P-L-P-G-K-S-C-S-G-K


### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels  and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-I-I-T-A-C-L-V-L-F-V-W-A-K-E-G-Y-L-V-N-K-S-T-G-C-K-Y-G-C-F-W-L-G-K-N-E-N-C-D-M-E-C-K-A-K-N-Q-G-G-S-Y-G-Y-C-Y-S-F-A-C-W-C-E-G-L-P-D-S-T-P-T-Y-P-L-P-N-K-S-C-S-K-K


### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels  and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-M-I-T-A-C-L-A-E-I-G-T-V-W-A-K-E-G-Y-L-V-N-K-S-T-G-C-K-Y-G-C-F-W-L-G-K-N-E-N-C-D-K-E-C-K-A-K-N-Q-G-G-S-Y-G-Y-C-Y-S-F-A-C-W-C-E-G-L-P-D-S-T-P-T-Y-P-L-P-N-K-S-C-S-K-K


### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels  and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-M-I-T-A-C-L-A-L-I-G-T-V-W-A-K-E-G-Y-I-V-N-Y-H-D-G-C-K-Y-E-C-Y-K-L-G-D-N-D-Y-C-L-R-E-C-K-L-R-Y-G-K-G-A-G-G-Y-C-Y-A-F-G-C-W-C-T-H-L-Y-E-Q-A-V-V-W-P-L-P-K-K-R-C-N-G-K


### FUNCTION Beta toxins bind voltage-independently at site-4 of sodium channels  and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ### SEQUENCE -M-N-S-L-L-M-I-T-A-C-L-A-V-I-G-T-V-W-A-K-E-G-Y-I-V-N-Y-Y-D-G-C-K-Y-A-C-L-K-L-G-E-N-D-Y-C-L-R-E-C-K-A-R-Y-Y-K-S-A-G-G-Y-C-Y-A-F-A-C-W-C-T-H-L-Y-E-Q-A-V-V-W-P-L-P-N-K-T-C-Y-G-K


### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-D-N-I-A-I-L-E-A-L-L-Y-T-S-G-D-E-G-L-E-Q-K-Q-I-I-D-I-L-D-I-N-L-N-Q-L-E-D-L-V-S-K-Y-H-S-H-G-L-T-I-Q-R-Y-G-S-T-Y-V-L-T-T-K-K-E-T-S-T-Y-I-E-Q-L-V-K-E-K-S-K-M-K-L-S-Q-A-A-M-E-T-L-S-I-I-A-Y-N-Q-P-L-T-R-G-D-I-E-M-I-R-G-I-N-S-D-G-A-V-K-T-L-I-A-R-G-L-V-E-A-K-D-V-D-H-S-R-S-H-H-L-I-T-T-D-L-F-L-N-V-F-G-I-E-N-L-D-A-L-P-T-T-E-E-D-E-A-E-M-D-E-F-F-S-N-L-V-N-Q-K-G-E-S-N-E


### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-T-P-L-S-K-I-E-A-L-L-F-V-A-G-E-D-G-L-S-L-R-Q-L-A-T-L-L-D-I-P-V-T-A-L-L-Q-Q-L-E-K-M-A-Q-K-Y-E-R-D-D-N-S-A-L-S-L-L-E-S-S-K-T-Y-K-L-V-T-K-K-D-Y-A-D-L-L-R-Q-Y-S-K-T-P-I-N-Q-S-L-S-R-A-S-L-E-V-L-S-I-I-A-Y-K-Q-P-I-T-R-I-E-V-D-N-I-R-G-V-N-S-S-S-A-I-S-K-L-Q-A-F-D-L-I-Q-E-A-G-K-K-E-V-L-G-R-P-N-L-Y-V-T-S-D-Y-F-L-D-Y-M-G-I-N-S-L-E-E-L-P-D-A-S-S-I-E-L-K-D-E-E-F-T-L-F-D-N-K-E-N-E-E-Q-I-S-E-N-V-K-E-E-N-E-N


### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-T-Y-L-G-S-I-E-A-L-L-F-V-A-G-E-D-G-L-S-L-R-Q-M-A-E-L-L-S-L-T-P-S-A-L-I-Q-Q-L-E-K-L-A-K-R-Y-E-E-D-D-D-S-S-L-L-L-L-E-T-A-Q-T-Y-K-L-V-T-K-D-S-Y-M-T-L-L-R-D-Y-A-K-A-P-I-N-Q-S-L-S-R-A-S-L-E-V-L-S-I-I-A-Y-K-Q-P-I-T-R-I-E-I-D-D-I-R-G-V-N-S-S-G-A-I-T-R-L-I-A-F-G-L-I-K-E-A-G-K-K-E-V-L-G-R-P-N-L-Y-E-T-T-N-Y-F-L-D-Y-M-G-I-N-Q-L-D-D-L-I-D-A-S-S-I-E-L-V-D-E-E-V-S-L-F-S-M-D-S-I-N-T-E-D-K-E-N-N-E-N


### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-A-D-R-L-T-Q-L-Q-D-A-V-N-S-L-A-D-Q-F-C-N-A-I-G-V-L-Q-Q-C-A-P-P-A-S-F-S-N-I-Q-T-A-I-N-K-D-Q-P-S-N-P-T-E-E-Y-A-Q-L-F-A-A-L-I-A-R-T-A-K-D-V-D-V-L-I-D-S-L-P-S-E-E-S-T-A-A-L-Q-A-A-S-L-R-Q-L-E-E-E-N-Q-E-A-A-A-R-L-E-E-V-V-Y-R-G-D-A-L-L-E-K-I-Q-T-A-L-A-D-I-A-Q-S-Q-L-R-T-R-S-G-A-P-S-Q-Q-T-P-P-E-S


### FUNCTION Involved in the biogenesis of the 60S ribosomal subunit Ensures the docking of GTPBP4/NOG1 to pre-60S particles ### SEQUENCE -M-R-I-E-K-C-Y-F-C-S-A-P-V-Y-P-G-H-G-M-M-F-V-R-N-D-C-K-V-F-R-F-C-R-S-K-C-H-K-N-F-K-K-K-R-N-P-R-K-T-R-W-T-K-A-F-R-K-S-A-G-K-E-L-T-V-D-N-S-L-E-F-E-K-R-R-N-T-P-V-K-Y-N-R-E-L-W-S-K-T-V-E-A-M-R-K-V-E-S-I-K-H-K-R-Q-A-R-F-I-M-N-R-L-K-K-G-K-E-L-E-K-A-A-D-I-S-E-V-K-K-N-I-H-L-I-K-A-P-H-A-G-Q-A-K-Q-L-E-D-K-M-V-Q-K-L-A-E-D-V-E-M-D-E


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-G-R-V-R-T-K-T-V-K-K-A-A-R-V-I-I-E-K-Y-Y-T-R-L-G-N-D-F-H-T-N-K-R-V-C-E-E-I-A-I-I-P-S-K-K-L-R-N-K-I-A-G-Y-V-T-H-L-M-K-R-I-Q-R-G-P-V-R-G-I-S-I-K-L-Q-E-E-E-R-E-R-R-D-N-Y-V-P-E-V-S-A-L-D-Q-E-I-I-E-V-D-P-D-T-K-E-M-L-K-L-L-D-F-G-S-L-S-N-L-Q-V-T-Q-P-T-V-G-M-N-F-K-T-P-R-G-A-L


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-Q-N-D-A-G-E-F-V-D-L-Y-V-P-R-K-C-S-A-S-N-R-I-I-G-A-K-D-H-A-S-I-Q-I-N-I-A-E-V-D-R-V-T-G-R-F-N-G-Q-F-K-T-Y-A-I-C-G-A-I-R-R-M-G-E-A-D-D-S-L-L-R-L-A-K-T-D-S-I-V-A-K


### FUNCTION May form part of 2 intersubunit bridges in the assembled ribosome Upon binding to MALSU1, intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation ### SEQUENCE -M-A-L-S-L-S-G-L-I-L-P-K-L-M-Q-Q-R-A-F-S-V-S-S-A-V-S-A-I-Q-K-L-T-R-V-R-V-V-D-N-S-T-L-G-N-A-H-H-H-R-P-P-K-V-I-H-V-Y-N-K-N-G-V-G-K-V-G-D-R-V-L-L-A-I-K-G-Q-K-K-K-A-I-I-V-G-H-K-M-P-G-A-R-M-T-P-R-F-D-S-N-N-V-V-L-I-E-D-N-G-N-P-T-G-T-R-I-K-A-P-L-P-T-H-L-R-K-L-E-G-E-Y-S-K-L-L-A-I-A-Q-R-F-V


### FUNCTION Component of the COP9 signalosome complex ### SEQUENCE -M-P-V-C-V-M-M-A-E-L-D-E-K-L-L-L-Q-F-E-T-Q-E-L-E-A-P-G-G-I-A-T-P-Q-V-Y-S-Q-L-L-V-L-Y-L-L-H-N-D-M-N-N-A-R-Y-L-W-K-R-I-P-Q-A-I-K-T-A-N-P-E-M-A-A-I-W-A-V-G-Q-R-I-W-Q-R-D-F-P-G-I-Y-S-A-I-A-A-Y-Q-W-S-E-S-I-L-P-V-M-E-A-L-R-E-S-T-R-R-R-A-Y-G-L-V-A-Q-A-Y-T-S-I-S-A-E-D-F-A-A-F-V-G-Y-S-V-E-E-A-V-K-G-V-V-S-H-G-W-Q-A-D-P-N-T-R-M-I-M-P-Q-K-P-D-P-P-P-V-S-L-V-P-N-E-Q-Q-L-A-R-L-T-D-Y-V-A-F-L-E-N


### FUNCTION Plays a role as translation enhancer and involved in cell cycle regulation ### SEQUENCE -M-F-K-K-F-D-E-K-E-N-V-S-N-C-I-Q-L-K-T-S-V-I-K-G-I-K-N-Q-L-L-D-Q-F-P-N-I-D-D-W-L-N-Q-I-M-P-K-K-D-P-V-K-I-V-R-C-H-E-H-I-E-I-L-T-V-N-G-E-L-L-F-F-R-Q-R-E-G-P-F-Y-P-T-L-R-L-L-H-K-Y-P-F-I-L-P-H-Q-Q-V-D-K-G-A-I-K-F-V-L-S-G-A-N-I-M-C-P-G-L-T-S-P-G-A-K-L-Y-P-A-E-S-D-T-V-V-A-I-M-A-E-G-K-Q-H-A-L-C-V-G-V-M-K-M-S-A-D-D-I-E-K-V-N-M-G-I-G-I-E-N-V-H-Y-L-N-D-G-L-W-H-M-K-T-Y-K


### FUNCTION As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane Similarly, the bag6/bat3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum The bag6/bat3 complex also plays a role in the endoplasmic reticulum-associated degradation , a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome ### SEQUENCE -M-I-L-T-V-K-P-L-Q-G-K-E-C-N-V-Q-V-T-E-N-E-K-V-S-T-V-K-E-L-V-S-E-R-L-N-I-P-A-S-Q-Q-R-L-L-Y-K-G-K-A-L-A-D-E-H-R-L-S-D-Y-S-I-G-P-E-A-K-L-N-L-V-V-R-P-A-G-E-R-S-S-G-A-V-G-T-S-S-A-N-N-D-K-G-G-S-G-V-W-Q-L-L-S-T-V-L-A-K-H-F-S-P-A-D-A-A-K-V-Q-E-Q-L-I-K-D-Y-E-R-S-L-R-Q-L-S-L-D-D-I-E-R-L-A-S-R-L-L-H-P-E-T-E-V-M-D-T-S-Y-M-D


### FUNCTION Specific component of the STT3A-containing form of the oligosaccharyl transferase  All subunits are required for a maximal enzyme activity ### SEQUENCE -M-E-T-L-F-S-L-P-F-T-V-L-E-C-P-N-V-K-L-K-K-P-S-W-L-H-M-P-S-A-M-T-V-Y-A-V-V-I-V-S-Y-F-L-I-T-G-G-I-I-Y-D-V-I-V-E-P-P-S-V-G-S-M-T-D-E-H-G-H-Q-R-P-V-A-F-L-A-Y-R-V-N-G-Q-Y-I-M-E-G-L-A-S-S-F-L-F-T-M-G-G-L-G-F-I-I-L-D-R-S-N-A-P-N-I-P-K-L-N-R-F-L-L-L-F-I-G-F-V-S-V-L-L-S-F-F-M-A-R-V-F-M-R-M-K-L-P-G-Y-L-M-G


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-K-A-S-G-T-L-R-E-Y-K-V-V-G-R-L-L-P-S-V-K-N-P-A-P-P-L-Y-R-M-R-I-F-A-P-N-H-V-V-A-K-S-R-F-W-Y-F-V-S-Q-L-R-K-M-K-K-A-S-G-E-I-V-Y-C-G-L-V-F-E-K-S-P-L-K-V-K-N-F-G-I-W-L-R-Y-D-S-R-S-G-T-H-N-M-Y-R-E-Y-R-D-L-T-T-S-G-A-V-T-Q-C-Y-R-D-M-G-A-R-H-R-A-R-A-H-A-I-Q-I-M-K-V-Q-V-I-A-A-N-K-C-R-R-P-A-I-K-Q-F-H-D-S-K-I-K-F-P-L-P-H-R-V-L-R-R-Q-H-K-P-R-F-T-T-K-R-P-N-T-F-F


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-V-Q-R-L-T-Y-R-R-R-L-S-Y-N-T-A-S-N-K-T-R-L-S-R-T-P-G-N-R-I-V-Y-L-Y-T-K-K-T-G-K-S-P-K-S-A-C-G-I-C-P-G-R-L-R-G-I-R-A-V-R-P-Q-V-L-M-R-L-S-K-T-K-K-H-V-S-R-A-Y-G-G-S-M-C-A-K-C-V-R-D-R-I-K-R-A-F-L-I-E-E-Q-K-I-V-V-K-V-L-K-A-Q-A-Q-T-Q-K-S-K


### FUNCTION Probable hormone that may attenuate cell proliferation and induce senescence in the central nervous system ### SEQUENCE -M-V-V-L-L-F-L-L-V-I-L-L-C-P-D-S-T-N-G-N-K-L-R-K-M-L-Q-K-R-E-A-V-E-P-S-K-P-I-V-S-V-K-E-S-K-A-N-E-F-L-N-S-L-K-R-P-K-R-Q-L-W-D-R-T-R-P-E-V-Q-Q-W-Y-Q-Q-F-L-Y-M-G-F-D-E-A-K-Y-E-D-D-M-S-Y-W-K-N-Q-G-R-G-G-S-E-Y-Y-G-G-F-H-Q-H-H-Y-D-E-D-A-A-I-G-P-R-N-P-Y-T-Y-R-H-G-A-G-V-N-Y-D-D-Y


### FUNCTION Regulates dendritic and spine growth and synaptic transmission ### SEQUENCE -M-A-K-S-L-R-S-K-W-K-R-K-M-R-A-E-K-R-K-K-N-A-P-K-E-L-A-R-L-K-T-V-L-A-K-G-S-N-V-L-M-D-D-V-K-E-I-A-T-V-V-P-A-K-K-I-N-E-K-M-D-L-D-V-D-A-P-E-G-E-S-S-K-M-D-T-E-L-K-R-N-K-K-N-L-R-D-Q-H-G-Q-Y-P-V-W-F-N-Q-R-Q-Q-K-K-L-K-S-Q-C-G-K-K-K-G-K-S-K-Q-A-K-K-L-A-W


### FUNCTION Molecular adapter that acts as a bridge between proteins, and which is involved skeletal muscle development Functions as signal transducer for MSTN during skeletal muscle regeneration and myogenesis ### SEQUENCE -M-A-C-G-A-T-L-K-R-S-M-E-F-E-A-L-M-S-P-Q-S-P-K-R-R-R-C-A-P-L-P-G-S-P-A-T-P-S-P-Q-R-C-G-I-R-P-E-I-Q-Q-G-Q-Q-Q-P-L-G-G-D-L-R-L-T-P-E-Q-I-L-Q-N-I-K-Q-E-Y-T-R-Y-Q-R-R-R-Q-L-E-G-A-F-N-Q-G-E-A-G-V-S-N-E-V-Q-A-S-C-S-S-L-T-A-P-S-S-P-G-S-L-V-K-K-D-Q-P-T-F-S-L-R-Q-V-G-I-L-C-E-R-L-L-K-D-H-E-D-K-I-R-E-E-Y-E-Q-I-L-N-I-K-L-A-E-Q-Y-E-S-F-V-K-F-T-H-D-Q-I-M-R-R-Y-G-A-R-P-T-S-Y-V-S


### FUNCTION May form with the serine/threonine protein phosphatase ctdnep1 an active complex dephosphorylating and activating lipins Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics May also indirectly regulate the production of lipid droplets and triacylglycerol ### SEQUENCE -M-N-S-L-E-Q-A-E-D-L-K-A-F-E-R-R-L-T-E-Y-V-S-C-L-Q-P-T-T-G-R-W-R-M-L-L-I-V-V-S-V-C-T-A-T-G-A-W-N-W-L-I-D-P-E-T-Q-K-V-S-F-F-T-S-L-W-N-H-P-F-F-T-I-S-C-I-T-L-I-G-L-F-F-A-G-I-H-K-R-V-V-A-P-S-I-I-A-A-R-C-R-T-V-L-A-E-Y-N-M-S-C-D-D-T-G-K-L-I-L-K-P-R-P-H-V-Q


### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-I-I-Y-K-D-C-I-T-E-D-E-M-F-S-D-I-Y-K-I-I-E-T-P-D-G-M-C-L-E-V-E-G-K-V-I-Q-R-E-E-G-A-I-D-D-A-L-I-G-G-N-A-S-A-E-F-Q-E-D-D-V-G-G-S-S-L-T-S-G-V-D-I-V-M-N-H-K-L-Q-E-T-G-F-T-K-D-S-Y-K-N-Y-I-K-D-Y-V-K-Q-L-K-A-H-L-E-K-T-N-P-E-R-V-N-T-F-M-K-G-A-Q-E-T-V-K-K-I-L-G-N-F-K-N-Y-Q-F-Y-T-G-E-R-M-N-P-D-G-M-V-G-L-L-D-Y-R-E-D-G-I-T-P-F-M-I-F-F-K-D-G-L-I-I-E-K-C


### FUNCTION Has no ubiquitin ligase activity on its own The ube2v2/ube2n heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63' This type of poly-ubiquitination does not lead to protein degradation by the proteasome Mediates transcriptional activation of target genes Plays a role in the control of progress through the cell cycle and differentiation Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage ### SEQUENCE -M-A-V-C-A-G-I-K-V-P-R-N-F-R-L-L-E-E-L-E-E-G-Q-K-G-V-G-D-G-T-V-S-W-G-L-E-D-D-E-D-M-T-L-T-R-W-T-G-M-I-I-G-P-P-R-T-N-Y-E-N-R-I-Y-S-L-R-L-E-C-G-P-K-Y-P-E-A-P-P-T-V-R-F-V-T-K-M-N-M-N-G-I-N-N-S-N-G-T-V-D-Y-R-S-I-P-V-L-A-K-W-Q-N-S-F-S-I-K-V-L-L-Q-E-L-R-R-L-M-M-S-K-E-N-M-K-L-P-Q-P-P-E-G-Q-T-Y-N-N


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-S-M-L-R-L-Q-K-R-L-A-S-S-V-L-R-C-G-K-K-K-V-W-L-D-P-N-E-T-N-E-I-A-N-A-N-S-R-Q-Q-I-R-K-L-V-K-D-G-L-I-I-R-K-P-V-T-V-H-S-R-A-R-C-R-K-N-T-L-A-R-R-K-G-R-H-M-G-I-G-K-R-K-G-T-A-N-A-R-M-P-E-K-L-S-W-M-R-R-M-R-I-L-R-R-L-L-R-R-Y-R-E-S-K-K-I-D-R-H-M-Y-H-S-L-Y-L-K-V-K-G-N-V-F-K-N-K-R-I-L-M-E-H-I-H-K-L-K-A-D-K-A-R-K-K-L-L-A-D-Q-A-E-A-R-R-S-K-T-K-E-A-R-K-R-R-E-E-R-L-Q-A-K-K-E-E-I-I-K-S-L-S-K-E-E-E-S-G-K-K


### FUNCTION Involved in the interconversion between alpha- and beta-L-fucoses ### SEQUENCE -M-V-I-L-K-G-I-P-S-V-L-T-P-E-L-L-Y-V-L-A-Q-M-G-H-G-D-E-L-V-L-A-D-A-N-F-P-T-S-S-V-C-K-C-G-P-V-E-I-R-A-D-G-V-R-I-P-E-L-L-K-A-I-L-K-L-F-P-L-D-T-Y-D-E-S-A-A-V-M-D-L-V-P-S-D-L-L-K-G-L-K-V-P-I-W-D-Q-Y-S-E-L-L-K-Q-A-G-S-D-G-N-M-K-P-V-E-R-F-A-F-Y-E-R-A-K-K-A-F-A-V-V-A-T-G-E-T-A-L-Y-G-N-L-I-I-K-K-G-V-I-P-P-E-E-Q-C


### FUNCTION Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation ### SEQUENCE -M-A-L-L-S-P-Y-S-K-V-P-E-L-N-T-A-T-V-L-L-V-E-N-E-E-E-L-Q-N-K-L-A-N-A-I-V-Q-H-E-K-D-F-N-V-N-V-R-L-A-K-K-L-P-L-P-V-E-N-K-E-A-R-P-R-I-D-L-I-V-F-I-V-S-L-L-S-E-R-S-L-Q-S-A-E-S-S-L-S-H-L-H-S-D-C-F-L-G-K-V-C-F-L-V-T-D-A-R-C-G-S-H-T-Q-E-R-L-V-S-V-R-K-L-A-A-S-H-H-C-P-V-I-C-A-E-H-R-T-A-D-G-V-S-A-A-A-L-R-L-L-N-I-L-Q-V-S-A-G-M-T-P-M-S-T-T-A-L-Y-L-S-T-L-T-R-C-S-L-T-S-D-L-Q-E-D-Y-L-Q


### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-E-C-A-K-T-G-T-C-N-C-G-G-S-C-T-C-T-K-C-S-C-K-S-C-K-K-S-C-C-D-C-C-P-S-G-C-S-K-C-A-S-G-C-V-C-K-G-K-T-C-D-T-S-C-C-Q


### FUNCTION Indispensable for the control of thyroid structure and metabolism May play some role in the biological processes of the immature fishes ### SEQUENCE -M-R-V-V-L-L-A-S-G-V-L-C-L-L-A-G-Q-V-L-S-I-C-S-P-V-D-Y-T-L-Y-V-E-K-P-E-C-D-F-C-V-A-I-N-T-T-I-C-M-G-F-C-Y-S-L-D-P-N-V-V-G-P-A-V-K-R-L-A-V-Q-R-G-C-T-Y-Q-A-V-E-Y-R-T-A-E-L-P-G-C-P-P-H-V-D-P-R-F-S-Y-P-V-A-L-H-C-T-C-R-A-C-D-P-A-R-D-E-C-T-H-R-A-S-A-D-G-D-R-C-S-K-P-L-L-L-H-M-H-A-Y-P-G-Q-S-N-H-I-Q-T-L


### FUNCTION Urotensin is found in the teleost caudal neurosecretory system It has a suggested role in osmoregulation and as a corticotropin-releasing factor ### SEQUENCE -M-M-W-K-L-L-L-L-F-A-L-L-L-T-V-L-E-P-L-L-G-H-P-V-V-Q-S-A-E-M-S-F-G-R-P-V-V-V-E-E-E-Q-A-L-N-P-E-E-L-S-F-S-E-Q-A-Y-L-S-H-D-A-A-G-F-G-Y-P-S-L-I-S-G-D-I-S-S-D-G-L-R-T-A-G-F-V-P-S-Q-A-V-K-E-A-L-L-E-K-P-L-W-S-R-F-L-G-S-R-K-Q-Y-H-K-R-G-S-N-T-E-C-F-W-K-Y-C-V


### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-E-C-S-K-T-G-N-C-T-C-G-G-S-C-T-C-K-N-C-S-C-T-S-C-K-K-S-C-C-S-C-C-P-S-G-C-S-K-C-A-S-G-C-V-C-K-G-K-T-C-D-T-S-C-C-Q


### FUNCTION Acts as a positive cofactor of GATA transcription factors to establish the identity of the ventral mesoderm during gastrulation Down-regulation in the dorsal mesoderm is necessary for the proper formation of this territory since, when present, lmo4 may bind ldb1 and restrict the availability of this cofactor for Spemman organizer transcription factors At neurula stages, suppresses primary neuron differentiation and modulates gene expression at the Isthmic Organizer of the midbrain-hindbrain boundary ### SEQUENCE -M-V-N-N-R-I-S-E-S-T-T-T-A-V-S-N-N-G-S-P-P-K-A-C-A-G-C-G-G-K-I-A-D-R-F-L-L-Y-S-M-D-R-Y-W-H-T-R-C-L-K-C-S-C-C-Q-A-Q-L-G-E-I-G-T-S-C-Y-T-K-S-G-M-I-L-C-R-N-D-Y-I-R-L-F-G-N-S-G-A-C-N-A-C-G-Q-S-I-P-A-S-E-M-V-M-R-A-Q-G-S-V-Y-H-L-K-C-F-T-C-A-T-C-R-N-R-L-V-P-G-D-R-F-H-Y-V-N-G-T-I-F-C-E-H-D-R-P-T-G-L-L-N-G-H-L-N-P-L-Q-S-N-P-L-Q-G-S-P-M-L-P-D-Q-K-V-C


### FUNCTION Seems to act as a signaling molecule involved in the maintenance of iron homeostasis Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages May also have antimicrobial activity ### SEQUENCE -M-K-A-F-S-V-A-V-V-L-V-I-A-C-M-F-I-L-E-S-T-A-V-P-F-S-E-V-R-T-E-E-V-G-S-F-D-S-P-V-G-E-H-Q-Q-P-G-G-E-S-M-H-L-P-E-P-F-R-F-K-R-Q-I-H-L-S-L-C-G-L-C-C-N-C-C-H-N-I-G-C-G-F-C-C-K-F


### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-T-C-L-N-C-P-E-V-F-C-K-K-F-Q-T-C-R-N-G-E-K-I-C-F-K-K-F-D-E-R-K-L-F-G-K-R-Y-R-R-G-C-A-A-T-C-P-E-A-K-P-R-E-I-V-Q-C-C-S-T-D-R-C-N-R


### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-T-C-L-N-C-P-E-M-F-C-G-K-F-Q-T-C-R-N-G-E-K-I-C-F-K-M-L-Q-Q-R-R-P-F-S-L-R-Y-I-R-G-C-A-A-T-C-P-G-T-K-P-R-D-M-V-E-C-C-S-T-D-R-C-N-R


### FUNCTION May be involved in redox reactions associated with the formation of disulfide bonds May contribute to the quality control of protein folding in the endoplasmic reticulum ### SEQUENCE -M-A-G-E-V-Y-L-L-W-L-L-P-L-L-Q-G-L-A-S-Y-G-A-E-L-S-S-E-A-C-R-E-L-G-F-S-S-N-L-L-C-S-S-C-E-L-L-G-Q-F-S-L-N-Q-L-D-L-P-C-R-Q-C-C-Q-E-E-A-Q-L-E-N-R-K-L-Y-P-G-A-I-L-E-V-C-G-U-K-L-G-R-F-P-Q-V-Q-A-F-V-R-S-D-K-P-K-L-F-R-G-L-Q-I-K-Y-V-R-G-S-D-P-V-L-K-L-L-D-D-N-G-N-I-A-E-E-L-S-I-L-K-W-N-T-D-S-V-E-E-F-L-S-E-K-L-E-R-I


### FUNCTION Exhibits natriuretic and vasodepressant activity Has cGMP-stimulating activity May help to regulate body fluid homeostasis in a variety of aquatic environments ### SEQUENCE -M-N-L-S-Y-L-V-A-C-G-L-M-I-T-L-L-S-V-R-M-G-A-K-P-L-S-Q-A-Q-Q-K-S-F-R-S-L-L-G-E-E-L-A-E-F-L-E-S-E-E-K-E-R-R-L-D-A-V-R-S-R-L-R-L-L-R-D-L-R-M-D-T-R-A-R-G-V-W-A-R-L-L-N-D-Q-P-V-P-R-R-H-K-T-G-I-K-K-G-G-S-S-R-S-G-C-F-G-H-K-M-D-R-I-G-T-I-S-G-M-G-C


### FUNCTION Exhibits natriuretic and vasodepressant activity Has cGMP-stimulating activity May help to regulate body fluid homeostasis in a variety of aquatic environments ### SEQUENCE -M-S-L-N-L-P-G-Y-A-L-F-F-I-L-L-V-A-S-S-G-A-K-P-A-P-D-L-Q-I-L-E-P-P-L-S-S-L-E-E-Q-E-E-M-Q-E-E-V-Q-E-K-V-Q-E-Q-Q-E-E-V-Q-E-K-V-Q-E-Q-Q-E-E-V-Q-E-Q-Q-E-E-V-Q-E-Q-Q-E-E-Q-Q-E-E-V-Q-E-R-G-R-G-T-G-D-V-L-L-R-A-Q-L-D-S-S-T-W-A-L-Q-K-D-D-V-L-M-R-L-F-K-D-L-L-R-T-S-K-R-S-R-S-R-Y-K-K-G-G-L-R-S-C-F-G-V-R-L-A-R-I-G-S-F-S-G-L-G-C


### FUNCTION Exhibits natriuretic and vasodepressant activity Has cGMP-stimulating activity May help to regulate body fluid homeostasis in a variety of aquatic environments ### SEQUENCE -M-A-A-S-S-S-S-F-V-P-L-V-L-L-F-L-A-I-P-V-E-P-R-P-S-M-T-R-D-E-A-Q-V-L-R-A-L-F-G-A-R-L-S-S-I-I-S-T-P-V-N-T-D-D-I-A-E-L-L-P-R-R-P-G-P-P-R-S-F-G-A-S-P-G-A-L-R-G-L-T-R-G-S-E-G-G-S-R-F-L-L-D-F-L-Q-Q-Q-S-K-T-T-R-R-G-R-S-S-M-V-G-G-R-G-C-F-G-M-K-I-D-R-I-G-S-I-S-G-L-G-C


### FUNCTION Exhibits natriuretic and vasodepressant activity Has cGMP-stimulating activity May help to regulate body fluid homeostasis in a variety of aquatic environments ### SEQUENCE -M-L-C-P-A-L-L-C-A-A-L-L-L-L-T-P-V-E-I-T-D-A-R-A-L-Q-Q-P-S-D-A-A-Q-F-M-E-Q-F-L-E-S-Y-N-D-L-L-T-L-D-D-L-E-N-M-L-N-S-H-P-E-D-Q-S-N-L-S-S-S-K-A-D-E-Y-P-K-W-A-E-A-D-T-P-W-L-R-L-L-R-G-A-L-A-N-Q-K-R-A-E-P-D-R-S-R-R-G-W-N-R-G-C-F-G-L-K-L-D-R-I-G-S-M-S-G-L-G-C


### FUNCTION Virion protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-R-G-C-D-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-Y-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V


### FUNCTION Envelope protein required for virus entry into host cell and for cell-cell fusion ### SEQUENCE -M-N-S-L-S-I-F-F-I-V-V-A-T-A-A-V-C-L-L-F-I-Q-G-Y-S-I-Y-E-N-Y-G-N-I-K-E-F-N-A-T-H-A-A-F-E-Y-S-K-S-I-G-G-T-P-A-L-D-R-R-V-Q-D-V-N-D-T-I-S-D-V-K-Q-K-W-R-C-V-V-Y-P-G-N-G-F-V-S-A-S-I-F-G-F-Q-A-E-V-G-P-N-N-T-R-S-I-R-K-F-N-T-M-Q-Q-C-I-D-F-T-F-S-D-V-I-N-I-D-I-Y-N-P-C-V-A-P-N-I-N-N-A-E-C-Q-F-L-K-S-V-L


### FUNCTION Has thioltransferase and dehydroascorbate reductase activities ### SEQUENCE -M-A-E-E-F-V-Q-Q-R-L-A-N-N-K-V-T-I-F-V-K-F-T-C-P-F-C-R-N-A-L-D-I-L-N-K-F-S-F-K-R-G-A-Y-E-I-V-D-I-K-E-F-K-P-E-N-E-L-R-D-Y-F-E-Q-I-T-G-G-R-T-V-P-R-I-F-F-G-K-T-S-I-G-G-Y-S-D-L-L-E-I-D-N-M-D-A-L-G-D-I-L-S-S-I-G-V-L-R-T-C


### FUNCTION Contributes to vaccinia virus virulence in mice but not to replication in cell culture ### SEQUENCE -M-D-P-V-N-F-I-K-T-Y-A-P-R-G-S-I-I-F-I-N-Y-T-M-S-L-T-S-H-L-N-P-S-I-E-K-H-V-G-I-Y-Y-G-T-L-L-S-E-H-L-V-V-E-S-T-Y-R-K-G-V-R-I-V-P-L-D-S-F-F-E-G-Y-L-S-A-K-V-Y-M-L-E-N-I-Q-V-M-K-I-A-A-D-T-S-L-T-L-L-G-I-P-Y-G-F-G-H-D-R-M-Y-C-F-K-L-V-A-D-C-Y-K-N-A-G-I-D-T-S-S-K-R-I-L-G-K-D-I-F-L-S-Q-N-F-T-D-D-N-R-W-I-K-I-Y-D-S-N-N-L-T-F-W-Q-I-D-Y-L-K-G


### FUNCTION Involved in host translation shutoff without degradating host RNA By suppressing host gene expression, facilitates the evasion from host type I interferon immune response ### SEQUENCE -M-N-N-S-K-D-N-P-F-C-G-A-I-A-R-K-A-R-I-Y-L-R-E-G-L-D-C-V-Y-F-L-N-K-A-G-Q-A-E-S-C-P-A-C-T-S-L-V-F-Q-G-K-T-C-E-E-H-K-Y-N-N-N-L-L-S-W-Q-A-V-R-Q-L-E-R-Q-M-P-Q-L-Q-S-S-N


### FUNCTION Regulates HCFC1 activity by modulating its subcellular localization Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus ### SEQUENCE -M-I-L-Q-Q-P-L-E-R-G-P-P-G-R-D-P-R-A-T-T-G-V-T-L-G-L-D-T-R-E-P-L-H-K-H-F-L-S-E-E-N-M-A-T-H-F-S-R-L-S-L-H-N-D-H-P-Y-C-S-P-P-V-T-F-P-E-A-L-P-P-L-R-S-P-C-P-E-L-L-L-W-R-Y-P-G-S-L-I-P-E-A-L-R-L-L-R-L-G-D-N-P-S-P-Y-Y-S-A-S-P-A-G-E-I-M-E-L


### FUNCTION Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation ### SEQUENCE -M-S-S-S-T-S-C-P-I-P-G-C-R-D-Q-L-P-D-G-Y-S-T-T-P-G-G-T-L-Y-A-T-T-P-G-G-T-R-I-I-Y-D-R-K-F-L-L-E-C-K-N-S-P-I-A-R-T-P-P-C-C-L-P-Q-I-P-G-V-T-T-L-P-A-V-P-P-S-K-L-E-L-L-K-E-Q-K-Q-T-E-V-E-I-T-D-D-E-Q-F-E-M-D-M


### FUNCTION Involved in the early part of the secretory pathway ### SEQUENCE -M-T-N-V-Y-S-L-D-G-I-L-V-F-G-L-L-F-V-C-T-C-A-Y-F-K-K-V-P-R-L-K-T-W-L-L-S-E-K-K-G-V-W-G-V-F-Y-K-A-A-V-I-G-T-R-L-H-A-A-V-A-I-A-C-I-V-M-A-F-Y-V-L-F-I-K


### FUNCTION Cytokine with immunoregulatory activity May promote the transition between innate and adaptive immunity Induces the production of IgG ### SEQUENCE -V-V-I-F-L-G-T-V-A-H-K-T-S-P-Q-R-P-D-R-L-L-I-R-L-R-H-L-V-D-N-V-E-Q-L-K-I-Y-V-N-D-L-D-P-E-L-L-P-A-P-Q-D-V-K-E-H-C-A-H-S-A-F-A-C-F-Q-K-A-K-L-K-P-A-N-T-G-S-N-K-T-I-I-S-D-L-V-T-Q-L-R-R-R-L-P-A-T-K-A-E-K-K-Q-Q-S-L-V-K-C-P-S-C-D-S-Y-E-K-K-T-P-K-E-F-L-E


### FUNCTION Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine  proteins that have critical roles in mRNA metabolism Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions ### SEQUENCE -M-A-D-N-Q-V-P-K-R-H-C-Q-Y-P-L-L-A-L-L-N-T-P-D-Q-P-I-P-H-H-V-P-T-T-P-Q-K-Q-S-R-A-R-R-R-L-E-N-E-L-E-S-T-A-Q-T-S-N-H-T-A-P-Q-T-P-W-A-V-T-T-T-G-T-S-V-T-I-T-T-R-T-K-D-G-T-Q-V-V-V-T-L-H-L


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-L-K-V-V-K-I-Q-L-P-A-G-K-A-N-P-A-P-P-V-G-T-V-L-G-P-T-G-V-N-I-M-M-V-C-K-E-Y-N-A-L-T-Q-G-Q-A-G-M-I-I-P-A-E-I-T-I-Y-E-D-R-S-F-S-M-K-I-K-T-A-P-V-A-E-L-L-K-R-E-A-G-I-S-K-G-S-G-E-P-N-K-S-K-I-G-S-I-T-E-E-K-L-R-E-I-A-E-Y-K-F-P-D-M-N-A-A-S-V-E-A-A-M-R-T-I-E-G-T-A-R-S-M-G-I-T-V-Q-K


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-M-I-N-E-Q-I-R-A-R-E-V-R-L-V-G-A-N-G-D-Q-L-G-I-K-S-R-N-D-A-L-D-L-A-A-N-L-N-L-D-L-V-L-V-A-P-N-A-K-P-P-V-C-R-I-M-D-Y-G-K-F-R-F-E-Q-Q-K-K-E-K-E-Q-R-K-N-Q-K-V-I-S-M-K-E-V-R-L-S-P-T-I-D-E-H-D-F-N-T-K-L-R-N-A-I-K-F-L-E-K-G-D-K-V-K-A-S-I-R-F-K-G-R-A-I-T-H-K-E-I-G-Q-R-V-L-D-R-F-S-E-A-C-A-E-V-S-T-V-E-S-K-P-K-M-E-G-R-S-M-F-L-V-L-A-P-K-N-D-K


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-L-G-L-D-V-G-T-K-T-V-G-V-A-I-S-D-E-M-G-W-T-A-Q-G-L-E-T-I-K-I-N-E-E-R-G-H-F-G-F-D-R-I-S-E-L-V-K-Q-Y-N-V-D-K-I-V-V-G-L-P-K-N-M-N-G-T-I-G-P-R-G-E-A-C-Q-Q-F-A-E-N-L-R-E-L-L-Q-L-D-V-V-M-W-D-E-R-L-S-T-M-A-A-E-R-L-L-I-S-A-D-V-S-R-K-K-R-K-Q-V-I-D-K-M-A-A-V-V-I-L-Q-G-F-L-D-R-K


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-L-L-I-D-F-I-D-E-T-E-E-V-K-E-E-Y-M-S-L-I-R-E-V-L-E-K-A-A-Q-M-E-N-I-E-D-G-A-E-V-S-V-T-F-V-D-N-E-R-I-R-E-I-N-R-D-Y-R-D-K-D-Q-P-T-D-V-I-S-F-A-M-E-E-M-G-E-G-E-M-E-I-V-G-A-E-M-P-R-M-L-G-D-L-I-I-S-I-P-R-A-K-E-Q-A-E-E-Y-G-H-S-F-D-R-E-L-G-F-L-A-L-H-G-F-L-H-L-L-G-Y-D-H-M-T-E-E-D-E-K-E-M-F-G-R-Q-K-E-I-L-E-A-F-G-L-G-R


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-V-N-D-F-R-T-G-L-T-I-S-V-D-N-A-L-W-Q-V-L-D-F-Q-H-V-K-P-G-K-G-A-A-F-V-R-S-K-L-R-N-L-R-T-G-S-V-Q-E-K-T-F-R-A-G-E-K-V-E-K-A-H-I-E-N-R-R-M-Q-Y-L-Y-A-S-G-E-A-H-V-F-M-D-N-G-T-Y-E-Q-I-E-L-G-E-K-Q-I-E-R-E-L-K-F-L-K-E-N-M-E-V-A-I-M-T-Y-Q-G-E-V-L-G-V-E-L-P-N-T-V-E-L-Q-V-T-E-T-E-P-G-I-K-G-D-T-A-S-N-V-T-K-P-A-T-L-E-T-G-L-V-V-Q-V-P-I-F-I-N-E-G-E-M-L-I-I-N-T-G-E-G-K-Y-V-S-R-A


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-S-W-S-K-V-K-Y-F-F-F-D-T-P-E-E-K-E-A-A-Q-Y-G-Y-E-K-E-Q-T-D-M-K-K-Q-Q-D-P-P-E-Q-Q-D-V-T-F-P-K-A-Q-P-K-Q-N-V-V-S-I-E-T-A-K-Q-S-S-K-V-V-L-L-E-P-R-T-Y-S-E-A-Q-G-I-A-D-H-L-K-G-R-R-A-V-V-I-N-L-Q-R-M-S-T-D-Q-A-V-R-I-V-D-F-L-S-G-T-V-Y-A-I-G-G-D-I-Q-K-I-G-P-K-T-F-M-C-T-P-E-N-V-D-I-V-G-A-I-S-E-L-F-G-E-E-E-E-T-N-I-K-R-W


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-G-Q-Q-V-L-K-S-S-N-E-K-M-E-K-A-V-A-A-Y-S-R-E-L-A-T-V-R-A-G-R-A-N-A-S-V-L-D-K-V-Q-V-D-Y-Y-G-A-P-T-P-V-V-Q-L-A-N-I-T-V-P-E-A-R-L-L-V-I-Q-P-Y-D-K-T-S-I-G-D-I-E-K-A-I-L-K-A-D-L-G-L-N-P-S-N-D-G-T-V-I-R-I-A-F-P-A-L-T-E-E-R-R-R-D-L-V-K-V-V-K-K-Y-A-E-E-A-K-V-A-V-R-N-V-R-R-D-G-N-D-D-L-K-K-L-E-K-A-G-E-I-T-E-D-D-L-R-G-Y-T-E-D-I-Q-K-E-T-D-K-Y-I-A-K-V-D-E-I-A-K-N-K-E-K-E-I-M-E-V


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-D-K-K-V-T-E-V-V-E-A-F-A-Q-P-I-V-E-E-L-N-L-E-L-V-D-V-E-Y-V-K-E-G-Q-D-W-F-L-R-V-F-I-D-S-E-K-G-V-D-I-E-E-C-G-A-V-S-E-R-L-S-E-A-L-D-K-E-D-P-I-P-H-L-Y-F-L-D-V-S-S-P-G-A-E-R-P-L-K-K-E-K-D-F-Q-Q-A-V-G-K-Q-V-A-I-K-T-Y-E-P-I-D-G-E-K-M-F-E-G-K-L-L-S-Y-D-G-T-T-I-T-L-L-L-T-I-K-T-R-K-K-E-I-Q-I-S-M-D-K-V-A-N-A-R-L-A-V-T-F


### FUNCTION Possible metal-dependent hydrolase ### SEQUENCE -M-N-D-L-R-Y-P-I-G-Q-F-T-Y-K-R-P-I-T-E-E-M-I-D-T-W-I-Q-E-I-E-D-L-P-N-E-L-T-K-A-I-K-D-L-D-Q-K-Q-L-D-T-P-Y-R-V-G-G-W-T-V-R-Q-V-V-H-H-V-V-D-S-H-M-N-S-Y-I-R-F-K-L-A-L-T-E-K-N-P-T-I-K-P-Y-K-E-E-K-W-A-E-L-P-D-S-K-L-P-V-D-V-S-L-V-M-L-D-S-L-H-K-R-W-V-N-L-L-Y-S-L-E-I-E-D-L-E-K-T-F-N-H-P-E-T-G-E-T-K-L-A-V-A-I-G-L-Y-A-W-H-G-R-H-H-T-A-H-I-T-S-L-R-K-R-L-N-W


### FUNCTION Negative regulator of protease production and sporulation ### SEQUENCE -M-K-S-G-E-K-D-Y-S-V-K-E-A-M-I-F-S-Q-R-I-A-Q-L-S-K-A-L-W-K-C-V-E-K-D-W-Q-Q-W-I-K-P-Y-D-L-N-I-N-E-H-H-I-L-T-I-A-Y-H-L-K-G-A-S-I-S-E-I-A-K-F-G-V-M-H-V-S-T-A-F-N-F-S-K-K-L-E-E-R-G-Y-L-V-F-S-K-K-E-D-D-K-R-N-T-Y-I-E-I-T-D-K-G-E-E-L-L-L-R-L-M-E-E-Y-D-P-E-N-N-S-V-F-N-G-A-L-A-L-R-N-F-Y-G-K-F-P-E-N-I-E-L-I-A-I-L-R-N-I-Y-G-Q-D-F-I-D-I-F-E-K-S-L-E-D-I-E-E-N-F-T-E-S-D-Q-K-L-V-K-K


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-D-D-V-I-E-V-E-G-T-V-L-E-T-L-P-N-A-M-F-K-V-E-L-E-N-G-H-V-V-L-A-H-V-S-G-K-I-R-M-N-F-I-R-I-L-P-G-D-K-V-T-V-E-L-S-P-Y-D-L-N-R-G-R-I-T-Y-R-F-K


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-R-G-G-M-G-N-M-N-N-M-M-K-Q-M-Q-K-M-Q-K-D-M-A-K-A-Q-E-E-L-G-E-K-T-V-E-G-T-A-G-G-G-M-I-T-V-I-A-N-G-H-K-Q-I-L-E-V-K-I-K-E-E-V-V-D-P-E-D-I-E-M-L-Q-D-L-V-L-A-A-T-N-D-A-L-K-K-A-D-E-L-S-N-S-T-M-G-K-F-T-K-G-L-N-L-P-G-G-M-F


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-S-I-D-M-K-K-K-H-R-I-K-K-N-D-E-F-Q-A-V-F-Q-K-G-K-S-N-A-N-R-Q-F-V-V-Y-Q-L-D-K-E-E-Q-P-N-F-R-I-G-L-S-V-S-K-K-I-G-N-A-V-V-R-N-R-I-K-R-M-V-R-Q-A-I-T-E-L-K-D-E-I-A-S-G-K-D-F-V-I-I-A-R-K-P-C-A-E-M-T-Y-E-E-V-K-K-S-L-I-H-V-F-K-R-S-G-M-K-R-I-K-K


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-K-Y-E-I-M-Y-I-I-R-P-G-V-E-E-E-A-Q-K-A-L-V-E-R-F-A-G-V-L-T-N-N-G-A-E-I-I-N-T-K-E-W-G-K-R-R-L-A-Y-E-I-N-D-L-R-E-G-F-Y-M-I-L-N-V-K-S-N-A-E-A-I-N-E-F-D-R-L-A-K-I-N-E-D-I-L-R-H-I-V-V-K-E-E-E-K


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-M-N-R-V-I-L-V-G-R-L-T-K-D-P-D-L-R-Y-T-P-N-G-V-A-V-A-T-F-T-L-A-V-N-R-A-F-A-N-Q-Q-G-E-R-E-A-D-F-I-N-C-V-I-W-R-K-Q-A-E-N-V-A-N-Y-L-K-K-G-S-L-A-G-V-D-G-R-L-Q-T-R-N-Y-E-G-Q-D-G-K-R-V-Y-V-T-E-V-L-A-E-S-V-Q-F-L-E-P-R-N-G-G-G-E-Q-R-G-S-F-N-Q-Q-P-S-G-A-G-F-G-N-Q-G-S-N-P-F-G-Q-S-S-N-S-G-N-Q-G-N-S-G-F-T-K-N-D-D-P-F-S-N-V-G-Q-P-I-D-I-S-D-D-D-L-P-F


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-G-R-K-G-G-R-A-K-R-R-K-V-C-F-F-T-A-N-G-I-T-R-I-D-Y-K-D-V-D-L-L-K-R-F-V-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-Y-Q-R-K-L-T-V-A-I-K-R-A-R-Q-M-A-L-L-P-Y-V-G-E


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-K-D-V-K-G-K-G-K-K-G-E-V-K-N-V-P-D-G-Y-A-N-N-F-L-L-K-Q-G-L-A-A-E-A-T-N-S-S-M-K-T-L-E-A-Q-K-R-K-E-E-K-D-A-A-A-E-L-E-N-A-K-E-L-K-E-T-L-E-K-L-T-V-E-L-K-A-K-S-G-E-G-G-R-L-F-G-S-I-T-S-K-Q-I-V-D-A-M-Q-K-S-H-K-I-K-L-D-K-R-K-F-E-M-D-D-A-I-R-A-L-G-Y-T-N-V-T-V-K-L-H-P-Q-V-T-A-T-V-K-V-H-V-S-E-Q


### FUNCTION Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA The LrgAB and CidA proteins may affect the proton motive force of the membrane May be involved in programmed cell death , possibly triggering PCD in response to antibiotics and environmental stresses ### SEQUENCE -M-A-K-M-S-T-K-K-V-Y-S-F-L-L-Q-A-F-I-F-S-A-I-M-L-I-S-N-I-I-A-T-H-L-P-I-P-M-P-S-S-V-I-G-L-V-I-L-F-S-L-L-C-L-K-V-I-K-L-E-Q-V-E-S-L-G-T-A-L-T-G-I-I-G-F-L-F-V-P-S-G-I-S-V-I-N-S-L-G-V-M-G-Q-Y-F-V-Q-I-L-T-V-I-V-V-A-T-V-I-L-L-A-V-T-G-L-F-A-Q-F-I-L-G-K-D-E-K-E-T-E-D-I-K-E-L-K-V-V-N-K-G-R-K-H-G-K-V-A


### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-D-F-K-Q-Y-S-P-E-E-L-K-E-C-S-M-I-E-V-V-H-S-V-L-G-D-K-K-Q-A-T-T-F-N-E-L-V-Q-E-I-A-Q-V-L-G-L-S-Q-E-Q-V-N-A-K-I-A-Q-F-Y-T-D-L-N-I-D-G-R-F-I-N-L-G-E-N-R-W-G-L-R-S-W-Y-P-Y-E-Q-I-D-E-E-I-L-P-Q-P-K-P-K-K-K-R-K-V-E-E-D-G-F-D-D-Y-I-E-E-D-E-D-D-F-D-D-A-D-V-N-E-D-E-D-D-D-V-E-D-L-D-K-V-L-E-E-E-D-G-D-D-D-D-L-D-D-L-D-E-D-D-D-D-F-A-E-E-E-L-E-Y-D-E-T-E-E-E-E-E-E-E-L


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-T-F-E-Q-L-I-P-L-I-I-M-A-F-A-L-G-M-D-A-F-S-V-S-L-G-M-G-M-M-P-L-K-L-R-Q-I-L-Y-I-G-M-T-I-G-I-F-H-I-I-M-P-F-I-G-M-V-L-G-R-F-L-S-E-K-Y-G-D-I-A-H-F-A-G-A-I-L-L-I-G-L-G-F-Y-I-V-Y-S-T-I-L-Q-N-E-E-T-R-T-A-P-I-G-I-S-L-F-V-F-A-F-G-V-S-I-D-S-F-S-V-G-L-S-L-G-I-Y-G-A-Q-T-I-I-T-I-L-L-F-G-F-V-S-M-L-L-A-W-I-G-L-L-I-G-R-H-A-K-D-M-L-G-T-Y-G-E-I-V-G-G-I-I-L-V-G-F-G-L-Y-I-L-F-P-I


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-P-T-L-L-L-G-A-S-I-P-F-G-T-I-A-Y-T-L-F-I-F-L-L-L-L-V-M-L-R-K-F-A-W-G-P-L-M-G-I-M-K-E-R-E-E-H-V-A-N-E-I-D-A-A-E-R-N-N-A-E-A-K-K-L-V-E-E-Q-R-E-M-L-K-Q-S-R-V-E-A-Q-E-L-I-E-R-A-K-K-Q-A-V-D-Q-K-D-V-I-V-A-A-A-K-E-E-A-E-S-I-K-A-S-A-V-Q-E-I-Q-R-E-K-E-Q-A-I-A-A-L-Q-E-Q-V-A-S-L-S-V-Q-I-A-S-K-V-I-E-K-E-L-K-E-E-D-Q-V-K-L-I-R-D-Y-I-K-E-V-G-E-A-R


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-N-G-I-V-A-K-R-Y-A-V-A-L-F-K-I-A-K-E-K-H-V-L-E-M-F-E-E-E-L-R-L-V-Q-N-V-Y-V-K-N-G-E-L-H-S-F-L-T-Q-P-N-I-S-K-E-Q-K-K-T-F-L-A-N-V-F-G-S-V-S-E-S-I-L-N-T-L-Y-I-L-I-D-N-K-R-I-D-I-L-P-E-I-A-D-E-Y-V-V-L-A-N-E-E-R-N-V-A-D-A-T-V-Y-S-T-R-L-L-S-E-E-E-K-L-N-I-A-E-A-F-A-K-R-T-G-K-D-A-I-R-V-K-N-V-V-D-E-D-L-L-G-G-I-K-V-R-I-G-N-R-I-Y-D-G-S-L-Q-G-K-L-A-R-I-Q-R-E-L-M-K-N-R


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-P-K-G-T-G-K-V-I-A-Q-N-K-K-A-F-H-D-Y-F-I-E-E-T-Y-E-A-G-L-V-L-Q-G-T-E-I-K-S-I-R-A-G-R-V-N-L-K-D-A-F-A-R-V-H-N-G-E-V-W-V-H-N-M-H-I-N-T-Y-E-Q-G-N-R-F-N-H-D-P-L-R-T-R-K-L-L-L-H-K-K-E-I-D-K-L-A-G-A-A-K-E-T-G-Y-A-L-V-P-L-R-I-Y-L-K-N-G-F-A-K-M-A-L-G-L-A-K-G-K-K-Q-Y-D-K-R-H-D-L-K-E-K-E-A-K-R-E-I-A-R-A-F-R-D-R-Q-K-M


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-E-A-L-L-V-A-T-G-G-F-F-G-A-I-T-R-F-A-I-S-N-W-F-K-K-R-N-K-T-Q-F-P-L-A-T-F-L-I-N-I-T-G-A-F-L-L-G-Y-I-I-G-N-G-V-T-T-G-W-Q-L-L-L-G-T-G-F-M-G-A-F-T-T-F-S-T-F-K-L-E-A-V-Q-L-L-N-R-K-N-I-S-T-F-L-L-Y-L-S-A-T-Y-I-I-G-I-L-F-A-F-L-G-M-K-L-G-G-I


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-S-N-L-F-K-E-V-R-K-L-I-Y-I-I-V-G-I-A-G-I-L-G-A-L-S-R-Y-Y-L-G-L-N-I-T-T-F-W-H-H-S-F-P-L-A-T-L-L-I-N-L-I-G-C-F-F-L-A-W-L-T-T-Y-I-A-R-L-N-I-L-P-S-E-V-I-T-G-I-G-T-G-F-I-G-S-F-T-T-F-S-T-F-S-V-E-T-V-Q-L-I-N-H-S-E-W-S-I-A-F-L-Y-V-S-C-S-I-L-G-G-L-I-M-S-G-L-G-Y-T-L-G-D-F-L-I-K-K-S-L-T-E-G-D-Y-S


### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-S-V-E-S-F-E-L-D-H-T-I-V-K-A-P-Y-V-R-H-C-G-V-H-N-V-G-S-D-G-I-V-N-K-F-D-I-R-F-C-Q-P-N-K-Q-A-M-K-P-D-V-I-H-T-L-E-H-L-L-A-F-N-L-R-K-Y-I-D-R-Y-P-H-F-D-I-I-D-I-S-P-M-G-C-Q-T-G-Y-Y-L-V-V-S-G-T-P-T-V-R-E-I-I-D-L-L-E-L-T-L-K-D-A-V-Q-I-T-E-I-P-A-A-N-E-T-Q-C-G-Q-A-K-L-H-D-L-E-G-A-Q-R-L-M-N-F-W-L-S-Q-D-K-D-E-L-E-K-V-F-G


### FUNCTION May be involved in the biosynthesis of molybdopterin ### SEQUENCE -M-S-V-T-E-H-K-K-Q-A-P-K-E-V-R-C-K-I-V-T-I-S-D-T-R-T-E-E-T-D-K-S-G-Q-L-L-H-E-L-L-K-E-A-G-H-K-V-T-S-Y-E-I-V-K-D-D-K-E-S-I-Q-Q-A-V-L-A-G-Y-H-K-E-D-V-D-V-V-L-T-N-G-G-T-G-I-T-K-R-D-V-T-I-E-A-V-S-A-L-L-D-K-E-I-V-G-F-G-E-L-F-R-M-I-S-Y-L-E-D-I-G-S-S-A-M-L-S-R-A-I-G-G-T-I-G-R-K-V-V-F-S-M-P-G-S-S-G-A-V-R-L-A-M-N-K-L-I-L-P-E-L-G-H-I-T-F-E-L-H-R-Q


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-W-N-E-F-K-K-F-A-F-K-G-N-V-V-D-L-A-V-G-V-V-I-G-A-A-F-G-K-I-V-S-S-L-V-K-D-I-I-T-P-L-L-G-M-V-L-G-G-V-D-F-T-S-L-H-F-G-Y-G-K-S-A-V-M-Y-G-N-F-I-Q-T-I-F-D-F-L-I-I-A-A-S-I-F-M-F-V-K-V-F-N-K-L-T-S-K-K-E-E-E-K-E-E-E-I-P-E-P-T-K-E-E-E-L-L-G-E-I-R-D-L-L-K-Q-Q-N-S-S-K-D-R-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-R-Y-T-G-P-A-W-K-L-S-R-R-L-G-I-S-L-S-G-T-G-K-E-L-E-K-R-P-Y-A-P-G-P-H-G-P-N-Q-R-K-K-L-S-E-Y-G-L-Q-L-Q-E-K-Q-K-L-R-H-M-Y-G-M-T-E-R-Q-F-R-R-T-F-D-Q-A-G-K-M-P-G-K-H-G-E-N-F-M-I-L-L-E-A-R-L-D-N-L-V-Y-R-M-G-L-A-R-T-R-R-A-A-R-Q-L-V-N-H-G-H-I-M-V-D-G-A-R-V-D-I-P-S-Y-R-V-K-P-G-Q-T-I-S-V-R-E-K-S-N-S-L-V-V-V-K-E-A-I-E-V-N-N-F-V-P-E-Y-L-T-F-D-A-D-K-L-E-A-T-Y-T-R-H-A-E-R-S-E-L-P-A-E-I-N-E-A-L-I-V-E-F-Y-S-R


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-S-C-S-H-N-G-T-R-V-L-D-S-R-P-V-D-E-G-R-S-I-R-R-R-R-E-C-E-S-C-L-S-R-F-T-T-F-E-R-V-E-E-S-P-L-I-V-V-K-K-E-G-T-R-E-E-F-N-K-E-K-I-L-R-G-L-I-K-A-C-E-K-R-P-V-S-L-R-Q-L-E-E-V-T-Q-S-V-E-R-E-L-R-N-L-G-I-S-E-V-K-S-D-M-I-G-E-I-V-M-E-E-L-R-D-I-D-D-V-A-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-L-N-V-F-I-E-E-L-K-D-I-L-Q-K-E-R-E


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-G-G-T-V-T-R-Q-R-R-K-K-V-I-K-L-A-K-G-Y-Y-G-S-K-N-T-L-F-K-V-A-N-Q-Q-V-M-K-S-L-M-Y-A-F-R-D-R-R-Q-K-K-R-D-F-R-K-L-W-I-T-R-I-N-A-A-A-R-M-N-G-L-S-Y-S-R-L-M-H-G-L-K-N-A-G-I-E-V-N-R-K-M-L-A-D-L-A-V-H-D-E-K-A-F-A-E-L-A-T-V-A-K-N-N-I-N


### FUNCTION Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring It is recruited early at mid-cell but it is not essential for cell division ### SEQUENCE -M-S-Q-Q-K-G-K-K-S-R-I-N-V-E-I-Y-G-Q-Q-Y-S-V-V-G-D-E-S-T-S-H-I-R-M-V-A-A-I-V-D-D-K-M-R-E-L-N-A-K-N-P-S-L-D-T-S-R-L-A-V-L-T-A-V-N-V-I-H-D-Y-I-K-L-K-E-E-H-E-K-L-K-E-S-M-T-K-K-G-M-E


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-K-V-T-K-A-D-I-V-I-S-A-V-K-P-E-Q-Y-P-D-S-D-L-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-K-I-L-N-R-K-K-L-V-R-I-S-S-K-P-G-K-T-Q-T-L-N-F-F-L-I-N-E-M-M-H-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-S-E-R-A-A-W-G-K-M-I-E-T-Y-F-T-T-R-E-Q-L-D-A-A-V-L-V-V-D-L-R-H-Q-P-T-S-D-D-V-M-M-Y-D-F-L-K-H-Y-E-I-P-T-I-I-I-A-T-K-A-D-K-I-P-K-G-K-W-Q-K-H-L-K-V-V-K-E-T-L-A-V-E-I-G-D-E-I-V-L-F-S-S-E-T-G-L-G-K-E-E-A-W-K-A-I-H-K-F-T-K-T-K-N-A


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-E-T-G-G-K-Q-I-K-V-E-A-G-Q-A-I-Y-I-E-K-L-D-V-E-A-G-E-T-V-T-F-D-K-V-L-F-V-G-G-E-N-V-K-V-G-S-P-V-V-E-G-A-T-V-T-A-K-V-E-K-Q-G-R-A-K-K-I-I-V-F-K-Y-K-A-K-K-N-N-R-K-K-Q-G-H-R-Q-P-Y-T-K-L-V-V-E-A-I-N-A


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-F-K-Q-H-I-A-I-V-P-D-Y-P-K-E-G-I-V-F-K-D-I-T-P-L-M-N-D-G-K-A-Y-K-A-A-T-D-A-I-V-E-Y-A-K-E-R-D-I-D-V-V-V-G-P-E-A-R-G-F-I-I-G-C-P-V-S-Y-A-L-E-V-G-F-A-P-V-R-K-L-G-K-L-P-R-E-V-I-T-V-D-Y-G-K-E-Y-G-K-D-V-L-T-I-H-K-D-A-I-K-P-G-Q-R-V-L-I-T-D-D-L-L-A-T-G-G-T-I-E-A-T-I-K-L-V-E-E-L-G-G-V-V-A-G-I-A-F-L-V-E-L-T-Y-L-D-G-R-K-M-L-D-G-Y-D-V-L-V-L-E-K-Y


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-T-E-K-T-Y-P-M-T-Q-E-G-K-Q-K-L-E-N-E-L-E-Q-L-K-T-V-R-R-K-E-V-V-E-R-I-K-I-A-R-S-F-G-D-L-S-E-N-S-E-Y-D-A-A-K-D-E-Q-A-F-V-E-G-R-I-T-Q-L-E-N-M-I-R-N-A-V-I-I-K-D-T-G-E-V-S-T-V-V-T-L-G-K-T-V-T-F-K-E-L-P-N-G-D-E-E-A-Y-T-I-V-G-S-A-E-A-D-P-F-E-G-R-I-S-N-D-S-P-I-A-K-S-L-L-G-K-Q-I-G-E-K-V-T-I-Q-T-P-G-G-E-M-Q-V-E-I-V-S-V-K


### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-R-K-I-G-I-I-G-G-T-F-D-P-P-H-Y-G-H-L-L-I-A-N-E-V-Y-H-A-L-N-L-E-E-V-W-F-L-P-N-Q-I-P-P-H-K-Q-G-R-N-I-T-S-V-E-S-R-L-H-M-L-E-L-A-T-E-A-E-E-H-F-S-I-C-L-E-E-L-S-R-K-G-P-S-Y-T-Y-D-T-M-L-Q-L-T-K-K-Y-P-D-V-Q-F-H-F-I-I-G-G-D-M-V-E-Y-L-P-K-W-Y-N-I-E-A-L-L-N-L-V-T-F-V-G-V-A-R-P-G-Y-T-L-H-T-P-Y-K-I-T-T-V-E-I-P-E-F-A-V-S-S-S-L-L-R-E-R-Y-K-E-K-K-T-C-K-Y-L-L-P-E-K-V-Q-V-Y-I-E-R-N-G-L-Y-E-S


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-A-K-L-S-E-E-R-R-A-H-N-A-S-I-K-S-D-M-R-S-A-V-K-T-V-E-A-L-V-T-N-N-D-L-E-N-A-K-E-A-F-K-T-A-S-K-K-L-D-K-A-A-R-K-G-L-I-H-Q-N-A-A-A-R-Q-K-S-R-L-A-K-Q-V-N-A


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-E-E-R-N-E-Q-V-V-E-E-V-K-E-A-Q-V-E-E-A-V-T-P-E-N-S-E-E-T-V-E-E-K-S-E-A-A-L-L-Q-E-K-V-D-E-L-Q-A-K-L-T-E-T-E-G-R-T-L-R-L-Q-A-D-F-E-N-Y-K-R-R-V-Q-M-D-K-Q-A-A-E-K-Y-R-A-Q-S-L-V-S-D-I-L-P-A-L-D-N-F-E-R-A-M-Q-V-E-A-T-D-E-Q-T-K-S-L-L-Q-G-M-E-M-V-H-R-Q-L-L-E-A-L-T-K-E-G-V-E-V-I-E-A-V-G-K-Q-F-D-P-N-E-H-Q-A-I-M-Q-V-E-D-S-E-F-E-S-N-A-V-V-E-E-F-Q-K-G-Y-K-L-K-D-R-V-I-R-P-S-M-V-K-V-N-Q


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-K-R-R-T-A-R-E-R-A-M-Q-A-L-Y-Q-M-D-I-T-G-E-L-E-P-K-V-A-V-E-N-T-L-D-E-G-E-E-T-N-E-F-L-E-S-L-V-V-G-F-V-E-N-K-E-A-I-D-E-A-I-R-Q-N-L-K-K-W-K-L-E-R-I-S-I-V-D-R-S-I-L-R-V-A-V-Y-E-M-K-Y-M-E-E-I-P-H-N-V-T-I-N-E-A-I-E-I-A-K-T-F-G-D-E-E-S-R-R-F-I-N-G-V-L-S-N-I-K-D-T-L


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-E-N-K-L-S-F-E-E-A-I-S-Q-L-E-H-L-V-S-K-L-E-Q-G-D-V-P-L-E-E-A-I-S-Y-F-K-E-G-M-E-L-S-K-L-C-D-E-K-L-K-N-V-Q-E-Q-M-A-V-I-L-G-E-D-G-E-L-E-P-F-T-A-L-G-D-E-A


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-G-Q-R-H-I-K-I-R-E-I-I-A-N-K-E-I-E-T-Q-D-E-L-V-D-I-L-R-N-E-G-F-N-V-T-Q-A-T-V-S-R-D-I-K-E-L-H-L-V-K-V-P-L-H-D-G-R-Y-K-Y-S-L-P-A-D-Q-R-F-N-P-L-Q-K-L-K-R-N-L-V-D-S-F-V-K-L-D-T-A-G-H-M-L-V-L-K-T-L-P-G-N-A-H-S-L-G-A-L-I-D-H-L-E-W-D-E-I-I-G-T-I-C-G-D-D-T-C-L-I-I-C-R-T-P-D-D-T-G-V-V-S-D-R-F-L-N-M-L


### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-D-R-K-E-Q-K-S-I-I-E-G-L-L-F-V-S-G-D-E-G-I-Y-P-E-Q-I-A-K-V-L-E-I-E-M-N-E-A-I-N-I-L-E-E-M-Q-Q-E-C-E-G-A-N-R-G-L-Q-I-V-Q-Y-A-K-V-Y-R-F-A-T-K-K-E-H-A-S-Y-Y-Q-K-L-I-D-T-P-T-A-A-S-L-S-Q-A-A-L-E-T-L-A-I-V-A-Y-R-Q-P-I-T-R-T-E-M-E-E-I-R-G-V-K-T-D-K-A-L-Q-T-L-V-S-H-L-L-I-K-E-M-G-R-A-E-G-P-G-R-P-I-L-Y-G-T-T-K-E-F-L-D-T-F-G-L-K-T-L-D-D-L-P-P-L-S-E-E-N-E-Q-M-N-E-A-D-L-F-F-G-C-L-Q-E-I-W-K


### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-F-K-V-F-Y-Q-E-K-L-T-E-V-P-V-R-E-N-T-K-V-L-Y-L-E-A-T-S-E-K-D-V-R-T-K-L-N-K-F-A-Y-N-I-E-F-V-Q-S-V-T-G-A-H-L-E-Y-E-K-E-N-A-D-L-T-L-A-E-I-V


### FUNCTION Essential cell division protein ### SEQUENCE -M-T-N-L-A-V-K-Y-K-Q-Q-A-Q-E-E-V-Q-I-Q-T-P-P-Q-Q-M-A-K-P-K-V-K-A-K-I-T-R-I-E-K-L-L-Y-V-A-F-I-G-F-L-L-Y-A-C-V-A-F-I-G-N-K-A-G-L-Y-Q-V-N-V-E-A-A-T-I-E-E-K-I-V-Q-Q-Q-K-E-N-Q-E-L-Q-A-E-V-E-K-L-S-R-Y-E-R-I-A-E-V-A-K-K-H-G-L-E-I-N-A-N-N-V-K-G-L-K


### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide  operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-Q-E-K-A-V-V-L-D-D-Q-M-I-R-R-A-L-T-R-I-S-H-E-I-V-E-R-N-K-G-V-D-N-C-V-L-V-G-I-K-T-R-G-I-F-I-A-Q-R-L-A-E-R-I-G-Q-I-E-G-K-E-M-E-V-G-E-L-D-I-T-L-Y-R-D-D-L-T-L-Q-S-K-N-K-E-P-L-V-K-G-S-D-I-P-V-D-I-T-K-K-K-V-I-L-V-D-D-V-L-Y-T-G-R-T-V-R-A-A-M-D-A-L-M-D-L-G-R-P-S-Q-I-Q-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-S-E-E-R-I-E-V-D-L-Q-E-T-D-Q-Q-D-R-V-S-I-Y-D-K


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-L-N-P-S-I-D-S-L-L-Q-K-I-D-S-K-Y-T-L-V-T-V-A-A-K-R-A-R-E-M-Q-L-A-N-N-C-V-V-E-K-P-V-S-H-K-C-V-G-K-A-L-E-E-I-D-A-E-A-L-S-Y-V-P-S-E-D-K-V-A-E


### FUNCTION Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism ### SEQUENCE -M-K-K-R-R-S-K-K-E-R-Q-E-L-L-Q-Q-T-I-E-S-N-P-F-I-T-D-E-D-L-A-E-K-F-Q-V-S-I-Q-T-V-R-L-D-R-M-E-L-S-I-P-E-L-R-E-R-I-K-H-V-A-T-K-Q-H-E-E-D-V-K-S-L-P-L-E-E-V-V-G-E-I-I-D-I-E-L-D-R-H-A-I-S-I-F-E-V-K-I-E-H-V-F-K-R-N-Q-I-A-R-G-H-H-L-F-A-Q-A-N-S-L-A-V-A-V-I-D-E-E-L-A-L-T-A-K-S-T-I-R-Y-I-R-P-V-K-L-G-E-R-V-V-A-K-A-R-V-E-D-V-E-N-D-K-G-R-T-V-V-K-V-R-S-F-V-G-E-E-L-V-F-T-G-T-F-E-M-Y-R-S-S-N-Y-S-E-E-G-N-N-L


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-D-V-L-E-R-V-T-K-I-I-V-D-R-L-G-V-E-E-T-E-V-V-P-A-A-S-F-K-E-D-L-G-A-D-S-L-D-V-V-E-L-V-M-Q-L-E-D-E-F-E-M-E-I-S-D-E-D-A-E-K-I-A-T-V-G-D-A-V-T-Y-I-E-S-H-L


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-T-K-W-F-N-V-G-K-I-V-N-T-H-G-V-R-G-E-I-R-V-I-S-R-T-D-F-P-E-E-R-Y-K-V-G-N-T-L-Y-I-S-N-E-K-G-T-D-Y-L-P-V-K-V-T-S-H-R-Q-H-K-T-F-D-L-L-T-F-E-G-Y-N-N-V-D-E-V-E-K-F-K-G-S-L-I-K-V-P-E-E-Q-L-G-E-L-A-E-G-E-Y-Y-Y-H-E-I-I-G-C-S-V-V-T-E-E-G-E-A-L-G-T-I-K-E-I-L-S-P-G-A-N-D-V-W-V-I-K-R-P-K-G-Q-D-L-L-I-P-Y-I-D-D-V-V-L-Q-V-N-I-E-N-K-L-V-T-I-H-V-M-E-G-L-L


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-Q-Q-L-I-A-E-I-T-K-G-Q-L-K-T-D-L-P-S-F-R-P-G-D-T-L-R-V-H-V-K-V-V-E-G-T-R-E-R-I-Q-L-F-E-G-V-V-I-K-R-R-G-G-G-I-S-E-T-F-T-V-R-K-I-S-Y-G-V-G-V-E-R-T-F-P-V-H-T-P-R-I-A-K-I-E-V-L-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-N-L-R-G-K-K-A-R-I-K-E-I-R


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-K-L-R-A-N-R-V-G-E-Q-M-K-K-E-L-G-D-I-I-S-R-K-I-K-D-P-R-I-G-F-V-T-V-T-D-V-Q-V-S-G-D-L-Q-I-A-K-V-Y-I-S-V-L-G-D-E-E-Q-K-E-N-T-L-K-G-L-A-K-A-K-G-F-I-R-S-E-I-G-Q-R-I-R-L-R-K-T-P-E-I-T-F-E-F-D-E-S-I-G-Y-G-H-R-I-D-T-L-L-H-E-I-N-K-D-G-K-R-E-E


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-Q-E-R-K-N-E-I-I-A-Q-F-R-T-H-E-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-E-Q-I-N-T-L-N-E-H-L-R-T-H-K-K-D-H-H-S-R-R-G-L-L-K-M-V-G-K-R-R-N-L-L-T-Y-L-R-N-S-D-I-T-R-Y-R-E-L-I-T-K-L-G-L-R-R


### FUNCTION Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation Inhibited by the antiholin-like proteins LrgAB In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential ### SEQUENCE -M-K-Y-V-T-L-L-L-Q-V-G-V-L-Y-V-F-S-L-V-G-T-W-I-Q-G-V-F-H-L-S-M-P-G-S-L-I-G-M-L-I-L-F-L-L-L-S-T-R-V-L-P-L-K-W-F-E-L-G-A-E-K-L-I-V-F-L-P-L-F-L-I-P-S-T-T-G-L-M-E-Y-G-S-F-L-F-S-K-E-S-I-I-F-L-L-V-V-A-S-T-V-V-T-L-I-V-S-G-Y-I-S-Q-L-L-I-T-T-K-K


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-K-Q-S-I-N-I-Q-D-Q-F-L-N-Q-L-R-K-E-N-T-F-V-T-L-Y-L-L-N-G-F-Q-L-R-G-L-I-K-G-F-D-N-F-T-V-L-L-E-T-E-G-K-Q-Q-L-I-Y-K-H-A-I-S-T-F-V-P-Q-K-N-V-S-I-E-L-E


### FUNCTION Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation Inhibited by the antiholin-like proteins LrgAB In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential ### SEQUENCE -M-K-W-W-K-L-S-G-Q-I-L-L-L-F-C-F-A-W-T-G-E-W-I-A-K-Q-A-H-L-P-V-P-G-S-I-I-G-I-F-L-L-L-I-S-L-K-F-N-L-V-K-K-E-W-I-Q-D-G-A-D-F-L-L-K-E-L-I-L-F-F-I-P-S-A-V-A-V-I-R-Y-R-D-T-L-T-Q-Y-G-I-D-L-I-L-I-I-M-I-S-T-L-C-V-T-L-V-T-G-L-L-T-E-L-L-L-K-R-K-G-S-T-Q


### FUNCTION Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization ### SEQUENCE -M-L-L-Q-G-T-H-R-I-G-R-M-A-M-L-L-A-L-A-D-E-N-E-S-P-V-L-S-I-P-K-G-W-K-Y-C-T-G-K-V-G-S-M-N-S-Q-K-V-V-A-A-M-E-T-A-A-K-S-N-Q-V-I-E-T-D-V-Y-R-E-T-H-A-L-Y-H-A-I-M-E-A-L-Y-G-V-T-R-G-Q-I-Q-L-A-D-V-L-R-T-V-G-L-R-F-A-I-V-R-G-T-P-Y-D-G-K-K-E-G-E-W-V-A-V-A-L-Y-G-T-I-G-A-P-V-K-G-S-E-H-E-A-I-G-L-G-I-N-H-I


### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-I-L-Y-T-T-A-S-C-A-S-C-R-K-A-K-A-W-L-E-E-H-Q-I-D-Y-I-E-K-N-I-V-S-N-S-M-T-V-D-E-L-K-S-I-L-R-L-T-E-E-G-A-T-E-I-I-S-T-R-S-K-T-F-Q-D-L-N-I-N-I-D-E-L-S-L-N-E-F-Y-T-L-I-I-E-H-P-L-M-L-R-R-P-I-M-L-D-E-K-R-L-Q-I-G-F-N-E-E-E-I-R-K-F-L-P-R-S-V-R-T-F-L-N-I-E-L-Q-K-L-A-N


### FUNCTION Catalyzes the reduction of arsenate ### SEQUENCE -M-E-N-K-K-T-I-Y-F-L-C-T-G-N-S-C-R-S-Q-M-A-E-A-W-G-K-Q-Y-L-G-D-K-W-N-V-Y-S-A-G-M-E-A-H-G-V-N-P-N-A-I-K-A-M-N-E-V-N-I-D-I-T-N-Q-T-S-D-I-I-D-A-N-I-L-N-S-A-D-L-V-V-T-L-C-S-H-A-D-S-V-C-P-S-T-P-P-H-V-N-R-V-H-W-G-F-D-D-P-A-G-K-E-W-S-E-F-Q-R-V-R-D-E-I-G-E-R-I-K-R-F-S-K-T-G-E


### FUNCTION Antitoxin component of a type II toxin-antitoxin  system Antitoxin that binds toxin SpoIISA and neutralizes its toxic activity Upon coexpression with SpoIISA in Ecoli normal growth is restored ### SEQUENCE -M-A-E-V-N-V-Q-K-S-S-F-F-K-E-K-K-E-E-S-N-T-D-F-S-L-V-K-G-A-L-T-E-N-I-N-R-L-E-K-L-M-N-N-S-S-S-K-Y-I-Q-V-K-R-T-K-E-N-A


### FUNCTION Can bind to ATTGG and CCAAT motifs  of single-stranded oligonucleotides ### SEQUENCE -M-T-L-T-G-K-V-K-W-F-N-S-E-K-G-F-G-F-I-E-V-A-D-G-N-D-V-F-V-H-F-S-A-I-T-G-D-G-F-K-S-L-D-E-G-Q-E-V-S-F-E-V-E-E-G-N-R-G-P-Q-A-K-N-V-V-K-L


### FUNCTION Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure ### SEQUENCE -M-E-Y-K-T-P-F-I-A-K-K-L-G-V-S-P-K-A-V-V-R-I-A-Q-Q-L-N-L-T-I-E-K-N-K-Y-G-H-F-I-F-T-Q-E-D-V-D-Q-M-L-E-H-H-R-F-Q-I-E-Q-S-Q-N-S-Q-S-T-Q-K-A-S-S-N-E-V-E-E-L-K-T-Q-V-N-T-I-V-Q-N-I-S-S-N-D-F-E-Q-L-A-N-Q-L-N-T-I-T-R-R-L-D-R-M-E-E-Q-M-Q-D-K-A-N-D-V-V-T-Y-Q-L-L-Q-H-R-R-E-M-E-E-M-L-E-R-I-Q-K-L-E-A-A-L-T-K-E-E-P-I-Y-I-T-P-D-S-K-P-T-Y-E-R-E-K-K-P-K-R-R-K-M-I-F-S-I-F-G-L


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-F-S-N-I-G-F-P-G-L-I-L-I-L-V-A-V-L-I-L-F-G-P-K-K-L-P-E-I-G-K-A-L-G-E-T-L-K-E-F-K-K-S-T-K-E-L-T-D-D-A-F-Q-E-K-E-K-K-E-K-M


### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-I-S-D-K-I-K-L-T-A-K-D-I-L-E-K-E-F-K-T-G-M-R-G-Y-Q-Q-E-E-V-D-K-F-L-D-M-I-I-K-D-Y-E-A-F-H-K-E-F-E-Q-L-K-Q-Q-N-A-R-L-K-R-E-L-E-E-Q-K-L-A-V-T-Q-V-P-Q-Q-P-V-Q-T-P-V-A-Q-P-V-Y-N-N-T-N-T-D-I-L-K-R-L-S-N-L-E-K-A-V-F-G-S-K-L-Y-E


### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-K-I-A-L-I-A-H-D-K-K-K-N-D-M-V-S-F-A-Y-A-Y-K-P-I-F-E-Q-H-E-L-F-A-T-G-T-T-G-L-R-I-M-E-A-T-G-L-V-I-T-R-Y-Q-S-G-P-L-G-G-D-Q-E-I-G-A-M-I-A-K-N-D-L-D-M-V-I-F-F-R-D-P-L-T-A-Q-P-H-E-P-D-V-N-A-L-L-R-L-C-D-V-Y-A-I-P-L-A-T-N-M-A-S-A-E-M-L-M-H-A-L-E-R-G-D-L-D-Y-R-K-L-R-K


### FUNCTION Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c ### SEQUENCE -M-K-K-N-R-L-L-F-R-V-I-I-L-L-I-L-C-G-A-V-G-F-T-L-Y-Q-G-F-F-A-N-K-E-K-M-Q-I-G-K-E-A-P-N-F-I-V-T-D-L-E-G-K-K-I-E-L-K-D-L-K-G-K-G-V-F-L-N-F-W-G-T-W-C-K-P-C-E-K-E-M-P-Y-M-N-E-L-Y-P-K-Y-K-E-K-G-V-E-I-I-A-L-D-A-D-E-T-D-I-A-V-K-N-F-V-N-Q-Y-G-L-K-F-P-V-A-I-D-K-G-Q-K-I-I-G-T-Y-G-V-G-P-L-P-T-S-F-L-I-D-K-D-G-K-V-V-E-Q-I-I-G-E-Q-T-K-E-Q-L-E-G-Y-L-K-K-I-T-P


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-M-E-P-F-R-I-H-K-G-T-A-A-V-L-M-N-D-N-I-D-T-D-Q-I-I-P-K-Q-Y-L-K-R-I-E-R-T-G-F-G-K-F-L-F-D-E-W-R-Y-D-N-N-R-Q-E-N-P-N-F-P-L-N-A-Q-E-R-K-G-A-S-I-L-I-T-G-D-N-F-G-C-G-S-S-R-E-H-A-P-W-A-L-A-D-Y-G-F-R-V-I-I-A-G-G-F-A-D-I-F-Y-M-N-C-M-K-N-G-M-L-P-I-V-M-D-K-D-M-R-E-Q-L-A-K-T-D-A-R-E-Q-I-T-V-D-L-E-N-E-I-M-T-T-N-T-H-R-F-H-F-T-I-E-K-M-W-K-E-K-L-L-N-G-L-D-E-I-S-I-T-M-Q-Y-E-Q-E-I-K-E-Y-E-R-K-V-A-L-H


### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid  by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-A-E-F-K-E-Q-V-L-D-I-L-E-E-V-C-E-N-D-I-V-K-E-N-L-D-V-Q-L-F-E-E-G-I-L-D-S-F-A-V-V-S-L-L-V-E-F-Q-E-R-L-D-I-E-V-S-I-S-D-F-D-R-D-E-W-A-T-P-N-M-V-I-K-K-L-E-E-I-R


### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-T-L-Y-S-S-P-S-C-T-S-C-R-K-A-K-L-W-L-E-E-N-H-I-P-Y-T-E-R-N-I-F-S-D-P-L-T-I-E-E-I-K-E-I-L-R-M-T-E-S-G-T-D-E-I-I-S-T-R-S-K-V-F-Q-E-L-N-V-N-L-E-S-L-P-L-Q-D-L-Y-K-M-I-R-D-Y-P-G-I-L-R-R-P-I-M-I-D-E-K-R-L-Q-V-G-Y-N-E-D-E-I-R-R-F-L-P-R-T-V-R-T-F-Q-L-R-E-A-Q-R-L-V-N


### FUNCTION Can bind to ATTGG and CCAAT motifs  of single-stranded oligonucleotides ### SEQUENCE -M-A-V-T-G-Q-V-K-W-F-N-N-E-K-G-F-G-F-I-E-V-P-G-E-N-D-V-F-V-H-F-S-A-I-E-T-D-G-F-K-S-L-E-E-G-Q-K-V-S-F-E-I-E-E-G-N-R-G-P-Q-A-K-N-V-I-K-L


### FUNCTION Negative regulator of sigma-B activity Phosphorylates and inactivates its specific antagonist protein, RsbV Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme ### SEQUENCE -M-M-E-R-F-E-K-I-E-M-K-I-P-A-K-A-E-Y-V-A-I-I-R-L-T-M-A-G-V-A-N-R-M-G-F-A-Y-D-D-I-E-D-M-K-I-A-I-S-E-A-C-T-N-I-V-Q-H-A-Y-K-E-D-V-G-E-I-A-I-V-F-G-L-Y-E-N-R-L-E-I-M-V-A-D-N-G-V-S-F-D-F-N-N-L-K-R-K-V-G-P-Y-D-I-S-K-P-V-E-H-L-P-E-N-G-L-G-L-Y-L-I-N-T-L-M-D-D-I-Q-I-M-H-D-E-G-M-T-V-L-M-T-K-Y-I-Q-R-E-Q-V-E-N-D-G-N-P-I-S-T-Y-E-S-Y


### FUNCTION Immunity component of an LXG toxin-immunity module Neutralizes the RNase activity of cognate toxin BC_0920 Probably does not have immunity protein activity on other toxins with the LXG domain ### SEQUENCE -M-K-Y-P-Y-S-F-E-V-L-T-N-G-K-L-V-M-R-L-P-Q-E-I-K-L-M-E-T-F-L-G-V-E-V-S-A-F-G-D-W-I-L-E-E-I-H-S-V-L-N-G-K-E-N-Y-V-V-V-N-G-N-I-C-G-L-E-I-R-K-D-T-T-T-V-L-D-N-L-A-E-D-G-K-G-D-F-C-E-I-E-T-I-E-L-V-D-L-I-H-I-W-Q-D-K-Q-K-E-F-K-K-G-K-N-K-E-L-K


### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-G-R-E-K-K-Q-E-Y-A-L-L-T-A-W-G-A-S-F-I-A-T-L-G-S-L-Y-F-S-E-I-M-K-F-E-P-C-V-L-C-W-Y-Q-R-I-F-M-Y-P-F-V-L-W-L-G-I-A-V-A-K-K-D-Y-R-I-A-S-Y-S-L-P-I-A-S-I-G-A-C-I-S-L-Y-H-Y-A-I-Q-K-V-A-A-F-S-A-A-G-A-A-C-G-R-V-P-C-T-G-E-Y-I-N-W-F-G-F-V-T-I-P-F-L-A-L-I-G-F-I-T-I-A-V-C-S-F-I-V-I-K-N-K


### FUNCTION Part of the high-affinity ATP-driven potassium transport  system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-E-K-K-Q-S-I-L-S-P-I-I-R-I-T-F-T-F-L-V-L-C-G-L-V-Y-P-L-I-V-T-G-I-A-Q-A-V-M-K-D-N-A-D-G-S-L-I-Y-N-D-K-N-E-V-I-G-S-K-L-I-G-Q-N-F-T-D-P-R-Y-F-Q-G-R-V-S-S-I-E-Y-K-A-E-A-S-G-S-N-N-Y-A-P-S-N-P-D-L-E-K-R-V-E-K-S-I-E-E-W-K-K-Q-N-P-S-V-P-V-T-E-V-P-I-D-L-V-T-N-S-G-S-G-L-D-P-D-I-S-P-K-A-A-S-V-Q-V-D-R-I-S-K-L-T-D-I-P-K-E-K-L-N-Q-L-I-K-D-Q-T-E-G-A-A-L-G-L-F-G-E-T-R-V-N-V-L-K-L-N-L-A-L-Q-E-L-M-K


### FUNCTION Regulates the transcription of the arc operon, involved in arginine catabolism ### SEQUENCE -M-K-K-E-K-R-Q-R-L-I-K-Q-F-V-K-E-Y-E-I-D-K-Q-E-R-L-V-E-L-L-A-K-K-D-V-L-V-T-Q-A-T-V-S-R-D-I-R-E-L-N-L-T-K-V-P-S-Q-E-G-L-M-I-Y-K-V-F-S-E-E-H-L-Q-T-D-I-K-L-K-K-K-L-R-E-V-V-V-K-I-D-C-V-D-Q-L-M-V-I-K-T-L-P-G-N-A-H-V-I-G-V-L-F-D-E-L-D-W-K-E-K-I-G-C-I-C-G-N-D-T-C-L-I-I-S-Q-S-K-S-D-R-E-I-I-E-E-R-L-N-L-I-I


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-I-G-I-G-I-D-I-I-E-L-N-R-I-E-K-M-L-D-G-K-L-K-F-M-E-R-I-L-T-E-N-E-R-N-V-A-M-E-L-K-G-S-R-L-T-E-F-V-A-G-R-F-A-A-K-E-A-Y-S-K-A-V-G-T-G-I-G-K-E-V-S-F-L-D-I-E-V-K-N-D-E-R-G-K-P-I-L-I-T-S-T-E-Y-I-V-H-L-S-I-S-H-S-K-E-F-A-V-A-Q-V-V-L-E-S-L-S-R


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-F-M-A-K-A-N-E-V-E-R-K-W-Y-V-V-D-A-E-G-Q-T-L-G-R-L-A-S-E-V-A-S-I-L-R-G-K-N-K-P-T-F-T-P-H-V-D-T-G-D-H-V-I-I-I-N-A-E-K-I-H-L-T-G-N-K-L-N-D-K-I-Y-Y-R-H-T-N-H-P-G-G-L-K-Q-R-T-A-L-E-M-R-T-N-Y-P-V-Q-M-L-E-L-A-I-K-G-M-L-P-K-G-R-L-G-R-Q-V-S-K-K-L-N-V-Y-A-G-A-E-H-P-H-Q-A-Q-K-P-E-V-Y-E-L-R-G


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-R-K-T-N-T-R-K-K-R-V-K-K-N-I-E-A-G-I-A-H-I-R-S-T-F-N-N-T-I-V-T-L-T-D-T-H-G-N-A-L-S-W-S-S-A-G-A-L-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-T-A-A-K-A-A-M-E-H-G-L-K-T-L-E-V-T-V-K-G-P-G-A-G-R-E-A-A-I-R-A-L-Q-A-A-G-L-E-V-T-A-I-R-D-V-T-P-V-P-H-N-G-C-R-P-P-K-R-R-R-V


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-E-G-S-R-K-V-R-N-R-V-G-R-G-I-G-S-G-N-G-K-T-A-G-K-G-H-K-G-Q-N-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-L-P-K-R-G-F-T-N-I-N-R-K-E-F-A-I-V-N-L-S-T-L-N-R-F-E-D-G-T-E-V-T-P-E-L-L-L-E-T-G-V-I-S-K-L-N-D-G-V-K-V-L-A-S-G-A-V-E-K-K-L-T-V-K-A-H-K-F-S-S-S-A-K-E-A-I-E-A-A-G-G-S-V-E-V-I


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-M-H-R-I-D-P-S-K-L-E-L-E-E-R-V-V-T-I-N-R-V-A-K-V-V-K-G-G-R-R-F-R-F-A-A-L-V-V-V-G-D-K-N-G-H-V-G-F-G-T-G-K-A-Q-E-V-P-D-A-I-R-K-A-I-E-D-A-K-K-N-L-I-A-V-P-L-V-G-T-T-I-P-H-T-I-N-G-H-F-G-A-G-E-V-F-L-K-P-A-A-E-G-T-G-V-I-A-G-G-P-V-R-A-V-L-E-L-A-G-V-Q-D-I-L-S-K-S-L-G-S-N-T-P-I-N-M-I-R-A-T-V-N-G-L-S-E-L-K-R-A-E-D-V-A-K-L-R-G-K-S-V-E-E-L-L-G


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-T-K-A-D-K-N-A-T-R-K-K-R-H-A-R-V-R-A-K-L-T-G-T-A-E-R-P-R-L-N-V-F-R-S-N-Q-H-I-Y-A-Q-V-I-D-D-V-N-G-V-T-L-V-S-A-S-T-L-D-K-D-L-A-L-N-G-T-S-N-I-E-A-A-T-K-V-G-E-S-V-A-K-R-A-V-E-K-G-V-K-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-A-G-L-Q-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-I-L-E-I-P-A-G-V-T-I-T-V-A-E-D-N-T-V-T-V-K-G-P-K-G-E-L-T-R-T-F-N-A-D-M-L-I-K-I-E-E-N-T-L-T-V-E-R-P-S-E-Q-K-E-H-R-A-L-H-G-T-T-R-A-L-I-G-N-M-V-E-G-V-T-E-G-F-A-R-G-L-E-L-V-G-V-G-Y-R-A-Q-K-Q-G-D-K-L-V-L-S-V-G-Y-S-H-P-V-E-M-T-P-E-A-G-L-E-V-E-V-P-A-P-T-K-I-V-I-K-G-I-D-K-Q-R-V-G-E-F-A-A-N-I-R-A-V-R-A-P-E-P-Y-K-G-K-G-I-R-Y-E-G-E-V-V-R-R-K-E-G-K-T-A-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-M-L-T-R-I-R-N-A-N-M-V-R-H-E-K-L-E-V-P-A-S-K-I-K-K-E-I-A-E-L-L-K-R-E-G-F-I-R-D-V-E-Y-I-E-D-N-K-Q-G-I-L-R-I-F-L-K-Y-G-A-N-N-E-R-V-I-T-G-L-K-R-I-S-K-P-G-L-R-V-Y-A-K-A-D-E-V-P-R-V-L-N-G-L-G-I-A-L-V-S-T-S-K-G-V-M-T-D-K-D-A-R-Q-L-Q-T-G-G-E-V-V-A-Y-V-W


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-Q-K-R-T-P-K-F-K-V-Q-E-Y-T-R-C-E-R-C-G-R-P-H-S-V-Y-R-K-F-K-L-C-R-I-C-F-R-E-L-A-Y-K-G-Q-I-P-G-V-K-K-A-S-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-E-K-F-Q-K-E-I-T-P-A-L-V-S-K-F-N-Y-K-S-V-M-Q-V-P-K-I-E-K-I-V-I-N-T-G-V-G-D-A-V-S-N-S-K-A-L-D-N-A-V-E-E-L-T-Q-I-T-G-Q-K-P-V-V-T-R-A-K-K-S-I-A-G-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-Q-M-Y-E-F-F-D-K-L-V-S-V-S-L-P-R-V-R-D-F-R-G-V-S-K-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-D-Y-D-K-V-S-K-V-R-G-M-D-I-V-I-V-T-T-A-K-T-D-E-E-A-R-E-L-L-T-Q-F-G-M-P-F-Q-K


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-H-V-K-K-G-D-K-V-Q-V-I-T-G-K-D-K-G-K-Q-G-V-I-L-V-A-F-P-K-Q-N-R-V-I-V-E-G-V-N-I-V-K-K-H-S-K-P-S-Q-L-N-P-Q-G-G-I-I-T-K-E-A-P-I-H-V-S-N-V-M-I-L-D-P-K-T-G-E-P-T-R-V-G-F-K-V-E-D-G-K-K-V-R-I-A-K-K-S-G-E-L-L-D-K


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-S-G-A-R-E-L-L-T-I-K-V-L-G-G-S-G-R-K-Y-A-N-I-G-D-I-I-V-A-T-V-K-Q-A-T-P-G-G-V-V-K-K-G-D-V-V-K-A-V-V-V-R-T-K-S-G-A-R-R-P-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-K-D-D-K-S-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-S-N-F-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-R-N-Q-R-K-V-Y-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-L-V-E-T-Y-K-T-H-S-L-Y-G-K-R-V-K-Y-S-K-K-Y-K-A-H-D-E-Q-N-Q-A-K-L-G-D-I-V-K-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-D-E-I-V-E-E-A-V-I-I


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-Y-R-R-E-H-R-G-K-M-R-G-R-A-K-G-G-T-E-I-A-F-G-E-F-G-L-Q-A-Q-A-A-S-W-I-T-N-R-Q-I-E-A-A-R-R-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-S-K-P-Y-T-A-K-P-L-E-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-V-V-K-P-G-K-I-M-F-E-I-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-A-H-K-L-P-V-K-C-K-F-V-K-R-E-E-N-G-G-E-S-N-E-N


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-Q-A-K-A-V-A-R-T-V-R-I-A-P-R-K-V-R-L-V-V-D-L-I-R-G-K-Q-V-G-E-A-I-A-I-L-N-H-T-P-K-T-A-S-P-V-V-E-K-V-L-K-S-A-I-A-N-A-E-H-N-Y-E-M-D-I-N-N-L-V-V-E-K-V-F-V-D-E-G-P-T-L-K-R-F-R-P-R-A-M-G-R-A-S-Q-I-N-K-R-T-S-H-I-T-V-V-V-S-E-K-K-E-G


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-L-K-K-G-P-F-V-D-D-H-L-M-S-K-M-E-K-L-V-A-S-E-Q-K-Q-V-V-K-T-W-S-R-R-S-T-I-F-P-Q-F-I-G-H-T-I-A-V-Y-D-G-R-K-H-V-P-V-Y-I-T-E-D-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-K-G-H-L-A-D-D-K-K-T-R-R


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-R-D-P-R-D-I-I-K-R-P-V-I-T-E-R-S-M-E-M-M-A-E-K-K-Y-T-F-D-V-D-V-K-S-N-K-T-E-V-K-D-A-L-E-A-I-F-G-V-K-V-E-K-V-N-I-M-N-Y-K-P-K-A-K-R-V-G-R-H-A-G-F-T-S-R-R-R-K-A-I-V-K-L-T-A-D-S-K-E-I-E-I-F-Q-G-V


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-K-E-K-I-R-I-R-L-K-A-Y-D-H-R-I-L-D-Q-S-A-E-K-I-V-E-T-A-K-R-S-G-A-T-V-S-G-P-I-P-L-P-T-E-K-T-V-Y-T-I-L-R-A-V-H-K-Y-K-D-S-R-E-Q-F-E-M-R-T-H-K-R-L-I-D-I-V-S-P-T-P-Q-T-V-D-S-L-M-R-L-D-L-P-S-G-V-D-I-E-I-K-L


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-A-K-R-D-V-L-P-D-P-M-Y-N-S-K-L-V-T-R-L-I-N-K-M-M-V-D-G-K-K-G-K-S-Q-T-I-L-Y-N-A-F-D-I-V-N-E-R-T-G-K-E-P-M-E-V-F-E-Q-A-L-K-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-A-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-N-Y-A-R-L-R-G-E-K-T-M-E-E-R-L-A-N-E-I-L-D-A-A-N-N-A-G-A-S-V-K-K-R-E-D-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-W


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-N-G-R-T-D-K-V-W-K-S-K-S-P-A-L-N-K-G-F-N-S-L-K-K-K-S-T-D-I-S-A-P-Q-K-R-G-V-C-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-Y-A-R-V-R-L-T-N-G-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-T-A-G-V-D-K-R-M-Q-G-R-S-K-Y-G-T-K-R-P-K-P-A-K-K


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-T-K-E-Q-I-I-E-A-V-K-S-M-T-V-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-V-A-G-G-A-G-E-A-A-A-E-K-T-E-F-D-V-E-L-T-S-A-G-A-Q-K-I-K-V-I-K-V-V-R-E-I-T-G-L-G-L-K-E-A-K-E-L-V-D-N-T-P-K-V-I-K-E-A-A-A-K-E-E-A-E-E-I-K-A-K-L-E-E-V-G-A-A-V-E-V-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-K-V-M-E-T-K-Q-Q-V-V-T-E-I-A-D-K-L-R-A-S-K-S-T-I-V-V-D-Y-R-G-L-T-V-S-E-A-T-E-L-R-K-Q-L-R-E-A-G-V-E-F-K-V-Y-K-N-S-L-T-R-R-A-A-E-S-A-E-M-A-E-L-N-E-F-L-T-G-P-N-A-I-A-F-S-N-E-D-V-V-A-P-A-K-V-L-N-D-F-A-K-D-H-E-A-L-E-I-K-A-G-V-I-E-G-K-L-V-T-L-D-E-V-K-A-I-A-T-L-P-S-R-E-G-L-L-S-M-L-L-S-V-L-Q-A-P-I-R-N-L-A-L-A-T-K-A-V-A-D-Q-K-E-E-Q-G-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-I-K-M-V-K-L-Q-I-P-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-A-G-V-N-I-M-G-F-C-K-E-F-N-A-R-T-A-D-Q-A-G-L-I-I-P-V-E-I-T-V-F-E-D-R-S-F-T-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-I-E-S-G-S-G-E-P-N-R-N-K-V-A-T-V-K-R-D-K-V-R-E-I-A-E-T-K-M-P-D-L-N-A-A-S-V-E-A-A-M-R-M-V-E-G-A-A-R-S-M-G-I-V-I-E-D


### FUNCTION Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 ### SEQUENCE -M-I-D-A-K-Q-L-N-S-L-A-L-A-Y-M-G-D-A-V-Y-E-Q-Y-I-R-Y-H-L-L-Q-K-G-K-V-R-P-N-Q-L-H-R-L-G-T-S-F-V-S-A-K-A-Q-A-K-V-V-Y-H-L-L-E-T-A-F-L-T-E-E-E-E-A-V-L-R-R-G-R-N-A-N-S-G-T-V-P-K-N-T-D-V-Q-T-Y-R-H-S-T-A-F-E-A-L-I-G-Y-H-H-L-L-N-N-R-E-R-L-D-E-I-V-Y-K-A-I-A-V-L-E-E-Q-E-G-G-T-S-S


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-V-G-L-G-N-P-G-R-E-Y-E-L-T-R-H-N-I-G-F-M-A-I-D-E-L-A-K-R-W-N-I-S-L-N-E-Q-K-F-K-G-V-F-G-A-G-F-V-N-G-E-K-V-I-L-L-K-P-L-T-Y-M-N-L-S-G-E-S-I-R-P-L-M-D-Y-Y-K-I-D-V-E-D-F-V-V-M-Y-D-D-L-D-I-P-V-G-K-L-R-L-R-M-K-G-S-A-G-G-H-N-G-V-K-S-T-I-S-H-L-G-T-Q-E-F-Q-R-I-R-M-G-I-D-R-P-K-N-G-M-K-V-V-D-Y-V-L-G-R-F-T-S-E-E-I-P-D-V-N-H-S-I-E-K-A-A-D-A-C-E-E-W-L-N-K-P-F-L-Q-I-M-N-T-F-N-S


### FUNCTION Essential for sporulation Interferes with or is a negative regulator of the pathway leading to asymmetric septation ### SEQUENCE -M-E-V-T-D-V-R-L-R-R-V-N-T-E-G-R-M-R-A-I-A-S-I-T-L-D-H-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-T-P-D-G-E-F-R-D-I-A-H-P-I-N-S-G-T-R-S-K-I-Q-D-A-V-L-T-E-Y-H-R-L-G-E-L-E-E-V-E-F-E-E-A-G-A-S


### FUNCTION Involved in initiation control of chromosome replication ### SEQUENCE -M-E-K-K-D-I-F-E-S-V-S-S-M-E-E-Q-I-G-H-L-Y-K-Q-L-G-E-L-K-Q-H-L-A-E-L-L-E-E-N-Q-H-I-K-M-E-N-N-N-L-R-H-R-F-E-E-V-Q-N-K-E-K-Q-K-T-Q-K-R-K-E-V-K-P-K-T-D-I-G-E-G-Y-D-N-L-A-R-L-Y-Q-E-G-F-H-I-C-N-L-H-Y-G-S-V-R-K-E-G-D-C-L-F-C-L-S-F-L-N-K-K


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-S-K-L-I-D-S-F-M-K-L-P-G-I-G-P-K-T-A-V-R-L-A-F-F-V-L-D-M-K-E-D-D-V-L-G-F-A-K-A-L-V-N-A-K-R-D-L-A-Y-C-S-V-C-G-H-I-T-D-R-D-P-C-Y-I-C-N-D-S-H-R-D-Q-S-V-V-C-V-V-Q-E-P-K-D-V-I-A-M-E-K-M-K-E-Y-Q-G-V-Y-H-V-L-R-G-A-I-S-P-M-E-G-I-G-P-E-D-I-N-I-P-Q-L-L-K-R-L-H-D-E-T-V-Q-E-V-I-L-A-T-N-P-N-I-E-G-E-A-T-A-M-Y-I-S-R-L-L-K-P-T-G-I-K-V-T-R-I-A-H-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-L-E-G-R-R-E-V


### FUNCTION Negative regulator of protease production and sporulation ### SEQUENCE -M-K-S-G-E-K-D-Y-S-V-K-E-A-M-I-F-S-Q-R-I-A-Q-L-S-K-A-L-W-K-C-V-E-K-D-W-Q-M-W-I-K-P-Y-D-L-N-I-N-E-H-H-I-L-T-I-A-Y-H-L-K-G-A-S-I-S-E-I-A-K-F-G-V-M-H-V-S-T-A-F-N-F-S-K-K-L-E-E-R-G-Y-L-V-F-S-K-K-E-D-D-K-R-N-T-Y-I-E-I-T-D-K-G-E-E-L-L-L-R-L-M-E-E-Y-D-P-E-N-N-S-V-F-N-G-A-L-A-L-R-N-F-Y-G-K-F-P-E-N-I-E-L-I-A-I-L-R-N-I-Y-G-Q-D-F-I-D-I-F-E-K-S-L-E-D-I-E-E-N-F-T-E-S-D-Q-K-L-V-K-K


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-V-G-I-G-I-D-I-I-E-L-N-R-I-E-K-M-L-D-G-K-L-K-F-M-E-R-I-L-T-E-N-E-R-N-V-A-K-G-L-K-G-S-R-L-T-E-F-V-A-G-R-F-A-A-K-E-A-Y-S-K-A-V-G-T-G-I-G-K-E-V-S-F-L-D-I-E-V-R-N-D-D-R-G-K-P-I-L-I-T-S-T-E-H-I-V-H-L-S-I-S-H-S-K-E-F-A-V-A-Q-V-V-L-E-S-S-S-S