### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-T-Q-S-I-V-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-N-I-G-D-V-I-K-V-S-I-K-E-A-I-P-R-G-K-V-K-K-G-D-V-M-H-A-V-V-V-R-T-R-K-G-V-R-R-N-D-G-S-L-I-R-F-D-N-N-A-V-V-L-L-N-N-Q-L-Q-L-V-G-T-R-V-F-G-P-V-V-R-E-L-R-T-D-K-F-M-K-I-I-S-L-A-L-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-N-K-N-E-K-M-V-R-S-L-M-G-T-V-V-S-N-K-M-N-D-T-V-V-V-R-V-E-R-R-V-K-H-P-K-Y-G-K-F-I-K-R-S-T-K-I-H-A-H-D-K-G-N-E-G-Q-I-G-D-I-V-T-I-R-E-C-R-P-I-S-K-T-K-S-W-T-L-V-K-I-N-E-R-A-E-K-V-E


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-S-N-R-K-Y-R-K-D-F-K-G-R-N-R-G-V-A-S-R-G-N-R-V-S-F-G-E-F-G-L-K-A-T-E-C-A-R-I-T-A-R-Q-L-E-A-A-R-R-T-I-A-R-H-I-K-R-G-G-K-I-T-I-R-I-F-P-D-K-P-I-T-K-K-P-L-E-V-R-Q-G-K-G-K-G-S-V-E-Y-W-V-A-L-V-Q-P-G-R-M-I-F-E-I-E-G-V-D-E-A-L-A-R-E-A-F-S-R-A-A-A-K-L-P-L-K-C-L-F-V-K-R-T-V-M


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-T-N-K-G-P-F-V-D-H-H-L-M-K-K-V-D-Q-A-Q-K-E-G-S-K-R-P-I-K-T-W-S-R-R-S-M-V-V-P-E-M-V-G-L-T-I-A-I-H-N-G-R-Q-H-V-P-V-Y-I-S-E-N-M-V-G-H-K-L-G-E-F-A-I-T-R-T-F-R-A-H-S-G-D-R-K-A-K-K-E-G-E-K


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-E-E-R-L-F-E-I-L-L-A-P-H-I-S-E-K-G-A-L-T-T-G-Q-Y-V-F-E-V-M-P-D-A-T-K-P-E-I-K-R-A-V-E-K-Q-F-N-V-T-V-K-S-V-R-T-C-N-V-K-G-K-T-T-R-F-R-Q-V-R-G-R-R-K-N-W-K-K-A-Y-V-M-L-A-P-G-S-E-I-D-I-A-A-G-E


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-D-N-Q-R-I-R-I-R-L-K-A-F-D-H-R-L-I-D-R-S-T-R-E-I-V-E-T-A-R-R-T-G-A-I-I-R-G-P-I-L-L-P-T-K-I-E-R-Y-T-V-L-I-S-P-N-I-D-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-L-V-D-I-S-E-P-T-D-K-T-V-D-A-L-M-K-L-D-L-A-A-G-V-D-V-Q-I-E-L-L-N-K-K-S-G-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-A-R-R-K-A-A-P-K-R-E-T-L-P-D-P-L-F-H-S-E-L-L-A-K-F-I-N-A-V-M-R-N-G-K-K-S-V-A-E-K-I-V-Y-G-A-L-D-V-V-A-K-R-V-Q-N-K-S-G-E-Q-G-D-G-D-G-E-S-G-G-K-A-G-G-I-K-K-R-S-L-G-D-I-R-T-D-E-N-A-R-A-L-A-L-E-T-F-K-G-A-L-D-K-V-M-P-N-V-E-V-K-S-R-R-V-G-G-S-T-Y-Q-V-P-V-E-I-R-M-A-R-R-Q-A-L-A-R-R-W-L-V-E-Y-A-N-K-R-N-E-K-T-M-V-L-R-L-A-H-E-I-L-D-A-V-E-G-R-G-G-A-I-K-K-R-E-D-V-H-R-M-A-K-A-N-Q-A-F-A-H-Y-K-W


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-L-N-L-E-Q-K-K-A-M-V-A-E-I-T-D-I-A-N-Q-A-V-S-A-V-A-A-D-Y-R-G-L-T-V-S-E-M-S-D-L-R-K-S-A-R-E-A-R-V-H-M-R-V-Y-R-N-T-L-A-R-R-A-F-K-E-T-T-Y-A-C-L-E-E-V-L-T-G-P-I-V-L-F-F-S-Q-E-E-P-G-A-A-A-R-L-I-E-K-F-I-K-E-H-E-R-L-E-V-K-G-L-A-L-G-G-E-L-L-P-A-E-K-L-K-A-V-A-R-L-P-S-R-E-E-A-L-S-Q-L-A-A-V-L-L-A-P-V-T-K-L-V-R-T-L-N-E-P-I-A-Q-V-A-R-V-M-A-A-V-R-D-Q-K-A-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-T-G-Y-I-R-L-Q-I-K-A-G-E-A-N-P-S-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-R-E-F-C-E-S-F-N-T-A-T-K-N-I-E-K-G-L-P-T-P-V-I-I-T-V-Y-A-D-R-T-F-S-F-I-T-K-T-P-P-A-S-V-L-L-K-K-F-V-L-K-G-K-S-G-S-A-R-P-N-T-E-K-V-G-K-A-T-R-Q-Q-L-E-E-I-A-K-M-K-T-P-D-L-T-A-A-D-L-E-A-A-I-R-T-I-A-G-T-A-R-S-M-G-I-D-V-E-G-V-E


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-N-T-A-T-R-V-I-V-A-Q-N-V-R-T-R-N-R-T-F-Q-I-T-K-Q-G-V-V-I-V-A-L-V-I-A-L-L-C-S-A-F-G-V-V-Y-F-K-D-L-N-R-R-L-F-I-Q-Y-Q-T-L-Q-R-E-K-A-E-E-L-I-Q-W-G-K-L-L-L-E-Q-T-T-W-S-T-Q-S-R-V-Q-R-I-A-E-Q-Q-L-G-M-Q-L-P-S-A-K-E-V-I-L-V-N-A-D-A-M-I-E


### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate  for the ubiquinone pathway ### SEQUENCE -M-K-K-Q-L-F-W-A-P-Q-N-E-I-P-S-T-L-W-T-A-N-E-R-S-W-L-T-H-P-G-S-L-T-Q-R-L-R-K-T-T-D-G-Q-I-Q-H-H-L-L-R-E-V-F-D-A-P-V-D-E-E-T-Q-L-L-G-I-S-Q-P-E-L-A-L-I-R-E-I-E-W-R-Y-F-E-S-L-W-V-A-G-R-V-V-I-P-K-K-T-L-E-R-E-G-S-P-L-N-H-I-G-E-R-S-L-G-D-I-L-F-A-N-A-K-F-T-R-G-D-L-E-F-R-Q-I-T-A-D-H-P-Y-Y-F-Y-V-K-E-I-A-N-G-S-C-I-W-A-R-R-S-L-F-Y-F-E-R-D-P-L-L-V-S-E-I-F-S-P-A-L-F-L-E-S-S-V-S-N-D


### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-V-L-T-R-T-N-G-Q-A-I-K-I-G-N-E-G-E-I-T-V-T-V-L-E-V-R-G-N-Q-V-R-M-G-I-D-A-P-K-H-I-A-V-H-R-E-E-I-Y-Q-R-I-Q-E-E-K-P-K-A-P-P-I-L-E-E-V-E


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-D-K-K-V-V-G-V-I-K-L-Q-I-Q-A-G-A-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-Y-N-A-A-T-E-S-Q-K-G-N-V-I-P-V-E-I-S-V-Y-E-D-R-S-F-T-F-V-L-K-T-P-P-V-V-E-L-I-K-K-A-A-R-I-S-K-G-S-P-T-P-H-N-L-K-V-A-Q-I-T-P-E-Q-V-K-S-I-A-E-A-K-M-V-D-L-N-A-N-D-I-D-A-A-S-K-I-V-R-G-T-A-R-S-M-G-V-T-V-A


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-T-K-Q-E-T-V-K-H-L-V-G-V-L-S-D-A-Q-A-I-V-F-T-E-Y-R-G-L-S-A-A-Q-L-R-A-L-R-I-L-L-R-G-D-A-S-Y-L-I-A-K-N-T-L-A-R-I-A-A-Q-Q-V-G-F-N-D-F-A-E-F-L-R-G-P-T-A-I-V-A-V-D-G-D-I-V-S-V-A-K-S-L-R-K-F-A-E-T-D-G-L-L-K-I-K-G-C-F-V-D-G-Q-V-F-G-S-E-H-V-K-R-L-A-E-L-E-S-R-E-V-I-L-A-K-I-A-S-V-T-K-G-A-L-S-S-A-L-G-L-V-S-A-P-L-S-S-A-A-R-V-F-V-A-M-K-N-T-F


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-K-E-D-G-M-A-K-I-T-T-D-E-L-I-E-S-F-K-E-M-T-L-I-E-L-S-E-F-V-S-K-F-E-E-V-F-K-V-T-A-A-A-P-V-A-A-A-A-A-P-V-E-P-A-A-E-A-A-P-E-K-T-T-F-D-V-I-L-E-A-A-G-D-K-K-I-Q-V-I-K-E-V-R-T-I-T-G-L-G-L-G-E-A-K-A-L-V-D-G-V-P-S-K-V-L-E-G-A-N-K-D-A-A-D-A-A-K-A-Q-L-E-A-A-G-A-Q-V-S-V-K


### FUNCTION Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis ### SEQUENCE -M-F-V-T-F-E-G-I-D-G-S-G-K-T-A-Q-L-T-A-A-G-E-F-L-K-A-S-G-K-Q-V-V-L-T-R-E-P-G-T-I-S-C-I-R-D-Y-V-L-A-S-D-M-D-I-R-T-E-A-L-L-Y-S-A-D-R-A-E-N-I-A-K-N-V-I-P-A-L-N-A-G-K-V-V-L-Q-D-R-Y-L-D-S-F-L-A-Y-Q-L-A-D-N-K-L-V-E-T-D-I-M-R-L-F-E-F-S-S-Q-G-L-R-P-D-L-T-L-L-F-D-L-T-P-A-C-A-Q-E-R-L-E-N-R-D-R-I-E-R-K-P-I-D-F-H-S-K-V-R-N-I-Y-L-K-L-S-A-D-N-T-D-R-I-R-V-I-D-A-S-Q-S-F-S-K-I-H-Q-Q-V-I-Y-H-I-E-R-K-L-G-G-T-H-S-A


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-G-K-D-R-N-L-S-L-N-S-P-E-S-I-Q-S-V-I-G-D-T-D-I-K-I-A-V-I-A-A-M-W-H-E-K-I-V-R-G-L-I-D-G-A-T-R-E-I-V-S-S-G-S-H-A-E-L-F-R-V-P-G-S-V-E-L-V-L-A-C-K-K-L-L-K-T-F-D-A-A-V-A-L-G-V-I-L-R-G-E-T-D-H-N-T-H-I-A-R-L-V-L-S-G-I-T-D-V-M-L-A-L-E-K-P-I-G-I-G-V-L-T-I-D-T-E-Q-Q-G-L-D-R-S-S-G-D-Y-N-A-G-V-N-A-A-R-A-V-I-R-M-V-R-L-F-R


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-V-R-R-E-I-P-E-D-P-V-Y-S-S-R-V-V-S-Q-L-I-G-R-V-L-L-S-G-K-K-S-L-A-Q-R-I-V-Y-S-A-L-D-K-V-S-M-K-A-S-E-D-P-V-S-V-L-R-K-A-L-D-N-V-R-P-S-L-E-V-R-S-R-R-V-G-G-S-T-Y-Q-V-P-V-P-V-R-S-H-R-A-D-A-L-A-I-R-W-L-T-V-Y-S-R-A-R-R-E-K-S-M-V-D-R-L-A-S-E-I-L-D-A-S-N-G-V-G-A-T-V-K-C-K-E-D-T-H-R-M-A-E-S-N-R-A-F-A-H-Y-R-W


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-V-Y-P-V-V-E-A-E-S-R-V-G-F-G-K-G-F-A-R-R-A-R-A-A-G-K-I-P-A-V-A-Y-G-L-K-R-A-P-E-H-V-L-L-P-A-A-Q-M-S-L-I-M-R-R-A-N-A-L-L-Q-L-K-I-D-A-R-E-S-L-V-L-I-K-Q-V-Q-R-D-R-I-R-N-I-I-E-H-L-D-M-L-F-V-N-E-D-D-A-V-T-I-R-V-P-L-R-F-V-G-Q-S-Y-A-G-T-V-T-S-V-E-N-Y-S-V-A-V-T-L-Q-V-S-Q-I-P-E-A-L-V-V-D-V-S-G-L-Q-A-G-R-R-I-F-A-S-D-I-A-L-P-D-G-A-L-L-V-S-P-P-R-L-L-I-A-K-V-D-P-V-R-R-A-T-Q-E-S-P-P-D


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-C-V-Y-I-V-A-G-L-G-N-P-G-P-S-Y-D-K-T-R-H-N-V-G-Q-M-V-L-D-I-L-S-G-G-A-R-F-R-R-H-K-T-N-N-F-Y-L-S-L-G-D-I-L-L-V-K-P-D-A-Y-M-N-L-S-G-P-V-I-A-S-L-M-K-F-H-S-V-S-D-L-L-V-L-H-D-D-I-D-L-P-L-G-T-L-R-F-K-Q-G-G-G-T-A-G-H-R-G-L-R-S-I-S-D-C-L-G-S-D-Y-A-R-L-R-V-G-I-G-R-P-E-N-N-Q-S-I-E-D-F-V-L-S-N-F-S-P-V-Q-T-D-I-I-S-R-T-I-Q-L-A-A-E-A-V-L-H-L-R-D-N-G-F-V-G-V-K-Q-F-I-A-Q-T-K-L-P-S-R-T


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-E-E-Q-K-I-R-I-R-L-K-S-Y-S-H-E-I-I-D-V-S-A-K-K-I-V-D-T-V-T-R-A-G-A-T-I-V-G-P-V-P-L-P-T-K-K-S-V-V-C-V-I-R-S-P-H-R-H-K-D-S-R-E-H-F-E-M-R-T-H-K-R-L-I-N-V-V-D-L-T-P-R-A-V-D-A-L-M-R-L-D-L-S-S-E-V-N-V-E-I-K-L


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-V-D-M-H-L-L-K-K-V-R-A-G-N-E-S-K-D-R-N-M-I-K-T-W-S-R-R-S-M-I-I-P-E-M-L-G-H-T-I-A-V-H-D-G-R-R-H-I-P-V-F-I-T-E-S-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-V-K-D-D-R-K-A-R-R-R


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-E-E-K-D-T-P-L-E-A-F-A-S-L-K-H-S-G-V-T-P-Q-K-V-R-R-I-V-D-L-I-R-G-R-S-V-D-E-A-L-A-I-L-R-F-S-P-H-S-A-S-G-I-L-Y-K-L-I-V-S-A-Q-A-N-Y-A-N-L-L-G-R-D-D-D-L-F-V-S-S-V-Y-V-D-E-G-K-T-Y-K-R-G-R-P-R-A-R-G-S-S-S-R-I-L-K-R-G-S-H-V-T-V-T-L-S-K-E-V-R


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-M-L-I-P-K-K-V-K-F-R-K-Q-H-R-P-N-R-K-G-M-S-G-C-G-T-R-I-V-F-G-D-Y-G-I-Q-A-L-S-R-A-Y-V-T-N-R-Q-V-E-S-A-R-I-A-M-T-R-H-I-R-R-G-G-R-V-W-I-N-I-Y-P-D-R-P-L-T-K-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-Y-W-V-A-N-I-R-P-G-R-I-M-F-E-V-S-G-V-S-E-S-L-A-K-E-A-L-M-R-A-I-H-K-L-P-L-R-A-R-I-V-E-R-Q-E-F-D-D-A-G-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-Q-Q-R-G-Y-R-K-S-R-R-G-Y-V-T-S-N-S-M-D-K-T-I-V-V-K-I-E-D-R-V-K-H-A-L-Y-G-K-V-I-R-K-T-S-K-V-K-A-H-D-Q-G-S-I-A-G-V-G-D-L-V-L-I-S-E-T-R-P-I-S-A-T-K-R-W-R-L-V-Q-I-L-E-K-A-K


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-T-G-A-K-S-L-S-V-I-R-V-L-G-G-S-N-R-R-F-G-S-L-G-D-V-V-V-A-S-V-K-D-A-V-P-G-S-S-A-V-K-K-G-D-V-V-K-A-V-I-V-R-S-T-K-E-V-R-R-T-D-G-S-Y-I-R-F-D-D-N-A-A-V-I-L-R-P-D-N-D-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-R-K-F-T-R-I-I-S-L-A-P-E-V-V


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-V-K-I-R-K-G-D-L-V-Q-V-I-T-G-S-K-T-G-G-K-K-G-K-Q-G-R-V-L-A-V-S-G-D-R-V-W-V-E-G-V-N-L-T-T-R-H-R-K-R-V-T-N-D-K-G-T-S-S-G-G-L-E-K-R-E-S-P-M-H-I-S-N-V-A-L-V-D-P-E-T-G-A-P-T-K-V-G-F-L-V-K-T-S-G-D-K-T-V-R-V-R-F-A-K-K-S-G-K-E-L-T


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-C-Y-T-P-R-L-L-T-R-Y-R-E-E-I-V-P-V-L-M-S-R-F-D-I-N-N-V-H-Q-V-P-S-I-T-K-I-V-V-N-S-G-V-G-D-A-A-R-D-S-K-I-I-E-G-A-V-S-D-I-T-L-I-T-G-Q-K-P-R-I-N-R-A-K-Q-S-I-A-K-F-K-L-R-E-G-Q-A-V-G-V-T-A-T-L-R-G-R-R-M-W-E-F-L-D-R-L-L-T-L-A-L-P-R-I-R-D-F-R-G-I-S-D-K-Q-F-D-G-H-G-N-Y-T-F-G-L-S-E-Q-G-I-F-H-E-I-D-Q-D-K-I-D-R-V-R-G-M-D-I-T-V-V-T-T-S-S-S-D-D-M-A-R-A-L-L-G-E-L-G-F-P-F-K-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-L-S-D-M-F-S-R-I-R-N-A-N-Q-V-L-H-K-K-V-T-V-P-S-S-R-L-K-V-S-I-A-D-L-L-K-R-E-G-Y-I-L-D-Y-S-V-I-D-E-H-P-G-Q-L-L-V-I-E-L-K-Y-G-P-D-K-S-R-A-L-V-G-L-K-R-V-S-K-P-G-L-R-V-Y-A-K-S-S-N-L-P-E-V-F-G-G-L-G-I-A-I-L-S-T-S-S-G-L-L-T-C-S-Q-A-R-K-K-G-V-G-G-E-V-L-A-Y-A-W


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-L-P-I-E-I-P-V-G-V-E-V-C-V-N-G-R-T-V-S-I-T-G-P-K-G-S-L-Y-L-D-I-A-E-Q-I-G-V-S-V-S-D-G-K-V-L-V-S-R-S-D-D-S-R-T-A-R-A-L-H-G-L-T-R-A-L-I-A-N-N-V-H-G-V-L-H-G-Y-T-K-T-L-E-I-V-G-T-G-Y-R-V-S-K-K-G-E-N-L-E-L-A-L-G-F-S-H-P-V-F-V-D-P-V-P-G-V-S-F-G-V-E-G-N-S-K-I-I-V-S-G-I-D-K-Q-A-V-G-E-A-A-A-S-I-R-K-L-S-K-P-E-P-Y-K-G-K-G-I-R-Y-S-D-E-I-V-R-R-K-V-G-K-A-G-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-L-T-S-R-A-S-A-R-K-R-R-H-V-R-L-R-K-K-I-S-G-T-C-D-R-P-R-L-S-V-T-R-S-N-R-H-V-F-V-Q-A-V-D-D-I-S-G-K-T-L-V-S-A-S-T-M-E-K-D-I-R-A-L-E-L-G-K-T-E-R-A-L-A-V-G-K-L-V-A-Q-R-A-L-A-V-G-V-K-S-A-V-F-D-R-G-G-C-K-Y-T-G-R-V-A-A-V-A-E-G-A-R-E-A-G-L-Q-T


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-I-K-L-H-H-L-R-P-A-P-G-S-R-R-A-R-V-R-V-G-R-G-E-G-S-K-G-K-T-A-G-R-G-T-K-G-T-K-A-R-A-P-V-R-P-G-F-A-G-G-Q-I-P-L-H-M-S-I-P-K-L-K-G-F-K-N-H-K-K-V-E-Y-S-V-I-S-I-K-R-L-C-E-A-Y-P-S-G-G-V-V-T-R-D-N-V-M-S-V-I-G-K-K-R-G-F-V-K-L-L-S-D-G-E-V-T-V-K-F-D-I-T-V-D-K-A-S-A-A-A-V-E-K-I-T-S-A-A-G-T-V-T-Q-A-R


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-K-D-G-V-I-E-L-E-G-S-V-L-E-A-L-P-N-A-T-F-R-V-E-L-S-N-G-H-K-V-L-A-H-I-S-G-R-M-R-Q-H-Y-I-R-I-L-P-E-D-R-V-V-V-E-L-S-P-Y-D-L-A-R-G-R-I-V-Y-R-Y-K


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-G-G-L-K-K-A-M-V-Y-L-G-L-A-E-D-N-Q-E-L-H-S-A-P-S-G-M-S-H-L-R-R-V-P-H-P-K-Q-Q-M-S-E-I-F-T-F-H-P-K-K-Y-S-E-V-S-G-I-V-E-R-F-R-Q-N-I-P-V-I-I-D-M-S-Q-L-S-D-T-D-A-R-R-M-I-D-F-A-S-G-L-S-Q-G-L-V-G-K-I-E-R-V-V-G-K-V-F-L-L-S-P-E-H-I-S-I-S-T-E-S-K-K-E-E


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-V-E-V-L-F-K-G-G-Y-T-P-Q-R-A-F-D-G-D-A-G-F-D-L-Q-S-S-H-T-A-V-I-Q-P-R-C-R-Q-V-V-K-T-G-I-A-I-A-L-P-D-G-Y-A-G-F-I-M-P-R-S-G-L-A-S-E-N-G-I-T-L-V-N-S-P-G-V-I-D-A-G-Y-R-G-E-I-S-V-V-L-I-N-T-D-L-H-Q-A-F-H-I-S-Q-G-D-R-I-A-Q-L-V-I-M-P-V-C-H-A-S-F-I-E-V-D-T-L-P-G-S-A-R-G-I-S-A-F-G-S-S-G-R-H-D-T-R-G


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-E-T-K-Q-T-V-F-D-R-L-L-Q-E-R-I-V-W-L-G-E-A-I-D-D-K-L-A-N-E-I-C-A-K-I-L-L-L-N-A-D-D-P-K-E-D-I-F-L-Y-I-N-S-P-G-G-S-I-T-A-G-M-A-I-Y-D-T-M-Q-F-V-S-N-D-I-V-T-V-G-I-G-M-A-A-S-M-G-Q-V-L-L-T-S-G-T-Q-N-K-R-Y-I-M-P-N-A-R-V-L-L-H-Q-P-L-A-G-F-G-G-T-A-S-D-I-Q-T-Q-A-K-L-I-L-D-M-K-Y-R-L-S-Q-I-T-A-S-R-T-G-K-T-V-E-Q-I-M-E-D-G-D-R-D-H-W-F-T-A-E-E-A-L-E-Y-G-F-V-D-H-I-R-T-E


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-V-K-A-S-G-F-Q-R-L-V-E-V-G-S-V-I-S-I-D-P-T-N-V-D-S-G-G-F-V-H-F-P-V-L-L-L-V-D-G-A-E-V-V-S-D-P-D-K-L-R-L-A-R-V-S-A-K-F-L-R-K-L-R-G-P-K-V-R-I-H-K-F-K-N-K-T-G-Y-H-K-R-Q-G-H-R-Q-G-V-Y-V-F-S-V-T-S-I-E-R-G-D


### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-G-G-T-F-D-P-I-H-H-G-H-L-V-V-A-S-E-V-A-S-R-F-C-L-D-E-V-I-F-V-P-T-G-R-P-P-H-K-K-E-V-S-D-P-W-H-R-Y-L-M-A-V-I-A-T-A-S-N-Q-R-F-S-V-S-K-I-D-I-E-R-T-G-P-T-F-T-V-D-T-L-R-E-L-R-E-Q-L-P-S-S-D-L-F-F-I-T-G-T-D-A-L-A-R-I-F-S-W-K-D-A-D-T-L-W-S-L-A-H-F-V-A-V-S-R-P-G-H-E-V-V-D-I-P-N-D-R-I-S-F-L-E-V-P-A-M-A-I-S-S-S-N-C-R-E-R-V-R-S-G-L-P-I-W-Y-L-V-P-E-G-V-V-Q-Y-I-A-K-H-G-L-Y-R-S-L-Y-G


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-H-A-L-D-A-L-D-A-L-S-I-K-A-D-I-P-D-F-S-P-G-D-T-V-R-V-Y-V-N-I-T-E-G-D-R-S-R-V-Q-V-F-Q-G-V-V-I-A-R-R-G-F-G-V-R-Q-T-F-T-V-R-K-I-S-F-Q-V-G-V-E-R-I-F-P-L-H-S-P-S-I-N-R-I-E-V-V-T-K-G-S-V-R-R-A-K-L-Y-Y-I-R-K-L-R-G-K-K-A-K-V-K-Q-K-R-E-L


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-G-I-M-C-S-G-D-V-S-E-R-M-N-K-T-I-E-L-L-K-E-Q-F-L-S-I-H-S-G-R-V-N-S-G-Q-F-E-K-V-M-V-D-C-E-G-A-S-V-P-L-V-S-L-A-S-I-R-V-L-N-A-N-T-I-V-V-T-P-Y-D-S-A-L-L-S-Q-I-D-R-A-L-R-N-V-P-N-I-G-T-P-G-N-D-G-E-C-I-K-I-V-M-P-Q-L-T-E-A-R-R-H-E-Y-V-K-Q-A-R-V-K-A-E-E-A-R-V-S-A-R-N-I-R-R-K-A-R-A-S-L-D-A-M-G-L-A-K-D-E-I-V-R-R-E-K-E-L-D-K-L-T-K-D-V-I-S-V-V-D-D-L-L-R-H-K-E-S-E-L-L-R-L


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-F-A-Q-P-H-N-P-L-L-P-S-V-P-D-I-V-F-S-A-I-V-L-A-I-V-L-P-F-F-W-W-F-V-I-P-R-I-S-K-L-L-S-D-R-S-S-L-I-E-G-K-I-S-E-A-A-S-A-H-A-R-A-L-E-T-L-E-L-R-K-Q-Q-L-D-E-A-K-S-E-A-S-Q-I-R-Q-E-A-R-D-D-A-Q-L-I-L-Q-Q-A-R-E-T-A-D-E-T-A-E-R-V-M-L-H-A-R-E-Q-I-Q-A-E-K-A-A-A-L-L-S-L-R-S-E-I-A-T-L-A-L-A-A-A-G-K-A-V-S-E-K-L-D-D-D-K-K-S-R-E-L-V-S-A-S-I-A-K-M-A-E-D-A-G


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-R-K-L-D-M-D-K-G-A-I-I-S-E-Y-G-L-S-K-G-D-T-G-S-P-E-V-Q-I-A-L-L-T-A-R-I-A-R-L-T-Q-H-L-K-E-H-S-F-D-H-H-S-R-R-G-L-M-L-M-V-G-R-R-R-R-L-L-S-Y-L-H-G-V-D-V-S-R-Y-R-A-I-L-S-N-L-G-L-R-R


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-C-V-A-P-T-P-S-H-L-V-W-V-D-C-E-M-T-G-L-N-P-E-R-D-E-L-L-E-V-A-V-V-V-T-D-K-D-L-L-P-L-D-E-G-V-N-V-V-V-S-P-S-S-E-A-L-G-A-M-D-N-Y-V-A-R-M-H-R-V-S-G-L-L-D-E-L-S-N-G-V-P-V-S-E-A-Q-A-M-V-K-E-Y-I-T-K-H-V-K-T-G-G-I-M-S-G-N-S-I-A-T-D-R-L-F-I-T-R-Y-M-P-D-V-H-A-I-L-H-Y-R-M-I-D-V-S-S-I-K-E-L-A-V-R-W-A-P-E-I-Y-S-G-A-P-N-K-K-G-G-H-R-A-M-A-D-V-L-E-S-I-A-E-L-A-Y-Y-R-E-H-F-L-T-G-T-A


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-V-K-S-V-A-D-R-F-F-L-G-L-D-F-G-S-T-R-I-G-V-A-R-N-C-G-S-L-A-V-P-V-G-V-L-P-R-A-S-C-A-E-I-L-G-Y-I-S-R-Y-S-I-D-E-V-V-I-G-L-P-L-T-L-A-G-K-E-K-Q-S-A-R-L-A-K-E-F-S-R-F-L-V-S-S-G-V-Q-V-R-F-F-D-E-R-F-T-T-V-I-A-T-Q-K-F-Y-S-L-G-K-G-V-K-Q-I-R-K-C-V-D-A-A-A-A-T-V-M-L-Q-L-F-L-D-M-E-V-K-V-D-P-L-E-R-K-P


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-G-L-L-Y-L-Q-N-S-S-G-Y-N-D-C-Y-F-K-T-E-S-L-V-D-F-L-Y-R-T-L-F-I-D-K-G-S-Y-L-G-V-S-F-I-T-A-A-E-M-R-D-L-K-I-K-H-F-G-V-N-E-D-S-D-V-L-S-F-P-I-D-E-I-A-P-G-S-E-N-S-L-V-Y-G-V-L-G-D-I-V-V-C-P-E-T-V-M-R-Q-A-V-R-H-P-F-E-H-E-I-Y-L-L-V-V-H-G-F-L-H-L-L-G-F-D-H-S-D-A-P-S-K-K-E-M-F-S-L-Q-A-K-L-I-E-D-F-F-A-L-E-N-L-G-T-P-S-E-E-I-T-I-T-P-D-L-R-P-S-L-G-R-I


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-I-K-R-N-R-T-N-E-N-N-R-L-R-N-K-A-V-K-S-E-L-K-T-L-I-R-L-V-K-R-A-A-R-D-N-D-L-P-R-A-E-D-A-L-R-R-A-S-L-K-L-D-R-A-V-S-K-G-V-I-H-P-N-Q-A-A-N-R-K-S-G-I-A-K-L-V-V-A-T-R-L-R-N-S-T-A-G-E


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-V-A-R-S-V-N-A-R-K-K-R-R-S-I-L-A-A-A-K-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-V-L-R-S-L-V-Y-A-Y-R-D-R-R-K-R-K-S-N-F-R-K-L-W-I-I-R-I-N-A-A-A-R-M-E-G-V-T-Y-N-R-F-L-Q-G-L-K-L-A-N-I-E-L-D-R-R-S-L-A-H-L-A-V-H-N-P-D-T-F-S-A-L-V-G-V-A-K-D-S-L-K-N-A-P-D-P-V-A-A-A-R-L-R-G-T-S-S-R-T


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-G-E-S-I-T-A-P-E-V-R-L-I-N-S-D-G-G-P-L-G-V-V-S-R-S-V-A-L-R-L-A-G-E-V-G-L-D-L-V-E-V-S-P-F-S-K-P-P-V-V-K-I-M-D-Y-G-K-F-R-Y-E-A-S-Q-K-A-K-E-A-R-R-R-Q-S-G-V-S-V-K-E-V-R-F-R-L-K-I-C-D-N-D-Y-D-V-K-L-R-K-A-I-S-F-L-Q-A-G-D-K-V-K-V-M-I-L-F-R-G-R-E-Q-S-R-P-E-L-G-V-K-L-L-K-K-F-A-D-D-I-S-E-F-G-S-A-D-S-L-S-R-T-D-G-R-G-M-A-I-M-V-S-P-I-K-S-K-T-I-V-R-E-K-S-S-H-A-Q-K-G-D-K-Q-P


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-S-K-L-S-K-I-V-K-N-E-K-R-K-V-I-V-A-R-Y-A-A-R-R-Q-E-L-K-R-I-I-A-A-P-G-T-A-P-E-R-R-D-E-A-Q-A-A-L-Q-K-L-P-R-D-A-S-P-V-R-V-R-S-R-D-V-V-D-G-R-P-R-G-I-L-S-R-F-G-V-S-R-I-R-F-R-E-M-A-H-R-G-E-L-P-G-I-T-K-S-S-W


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-L-G-S-P-L-R-E-Y-E-L-L-V-S-L-G-S-E-F-E-P-E-A-E-S-R-V-R-S-L-F-T-P-V-E-P-E-G-V-T-V-K-H-L-D-V-L-G-I-R-K-F-A-Y-E-I-K-G-R-N-D-G-V-C-V-V-V-R-F-L-A-N-A-G-S-I-A-E-I-G-R-Q-M-R-L-T-E-D-V-I-R-T-K-L-L-R-V-G-R-K


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-G-Y-R-A-K-G-R-R-Q-P-K-A-D-S-V-V-A-P-P-K-R-V-S-I-K-G-L-D-Y-K-D-L-A-S-L-K-R-F-L-S-D-R-G-K-I-R-A-R-R-V-T-G-A-S-I-Q-Q-Q-R-Q-I-A-K-A-I-K-N-A-R-E-M-G-V-I-P-F-K-S-G-V-S-R


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-R-V-I-L-V-Q-D-V-N-G-L-G-S-V-G-D-V-V-E-V-K-A-G-Y-S-R-N-Y-L-V-P-K-G-M-A-V-R-W-T-E-G-A-Q-K-H-I-G-D-I-S-A-A-R-R-A-R-E-A-A-A-L-Q-E-A-R-D-I-A-N-T-L-A-K-E-A-V-T-R-E-L-R-L-A-A-N-A-G-E-D-G-R-L-F-G-S-V-T-A-A-N-I-A-K-V-L-S-S-A-S-G-H-K-I-D-R-G-K-I-E-I-D-S-P-I-K-T-L-G-E-H-T-V-K-V-K-L-H-P-N-V-K-V-D-I-N-V-V-V-Y-A-E


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-D-K-K-V-V-G-V-I-K-L-Q-I-Q-A-G-A-A-N-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-Y-N-A-A-T-E-S-Q-K-G-N-V-I-P-V-E-I-S-V-Y-E-D-R-S-F-T-F-V-L-K-T-P-P-V-V-E-L-I-K-K-A-A-R-I-S-K-G-S-P-T-P-H-N-L-K-V-A-Q-I-T-P-E-Q-V-K-S-I-A-E-A-K-M-V-D-L-N-A-N-D-I-D-A-A-S-K-I-V-R-G-T-A-R-S-M-G-V-T-V-A


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-T-K-Q-E-T-V-K-H-L-V-G-V-L-S-D-A-Q-A-I-V-F-T-E-Y-R-G-L-S-A-A-Q-L-R-A-L-R-I-L-L-R-G-D-A-S-Y-L-I-A-K-N-T-L-A-R-I-A-A-Q-Q-V-G-F-N-D-F-A-E-F-L-R-G-P-T-A-I-V-A-V-D-G-D-I-V-S-V-A-K-S-L-R-K-F-A-E-T-D-G-L-L-K-I-K-G-C-F-V-D-G-Q-V-F-G-S-E-H-V-K-R-L-A-E-L-E-S-R-E-V-I-L-A-K-I-A-S-V-T-K-G-A-L-S-S-A-L-G-L-V-S-A-P-L-S-S-A-A-R-V-F-V-A-M-K-N-T-F


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-I-T-T-D-E-L-I-E-S-F-K-E-M-T-L-I-E-L-S-E-F-V-S-K-F-E-E-V-F-K-V-T-A-A-A-P-V-A-A-A-A-A-P-I-E-P-A-A-E-A-A-P-E-K-T-T-F-D-V-I-L-E-A-A-G-D-K-K-I-Q-V-I-K-E-V-R-T-I-T-G-L-G-L-G-E-A-K-A-L-V-D-G-V-P-S-K-V-L-E-G-A-N-K-D-A-A-D-A-A-K-A-Q-L-E-A-A-G-A-Q-V-S-V-K


### FUNCTION Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis ### SEQUENCE -M-F-V-T-F-E-G-I-D-G-S-G-K-T-A-Q-L-T-A-A-G-E-F-L-K-A-S-G-K-Q-V-V-L-T-R-E-P-G-T-I-S-C-I-R-D-Y-V-L-A-S-D-M-D-I-R-T-E-A-L-L-Y-S-A-D-R-A-E-N-I-A-K-N-V-I-P-A-L-N-A-G-K-V-V-L-Q-D-R-Y-L-D-S-F-L-A-Y-Q-L-A-D-N-K-L-V-E-T-D-I-M-R-L-F-E-F-S-S-Q-G-L-R-P-D-L-T-L-L-F-D-L-T-P-A-C-A-Q-E-R-L-E-N-R-D-R-I-E-R-K-P-I-D-F-H-S-K-V-R-N-I-Y-L-K-L-S-A-D-N-T-D-R-I-R-V-I-D-A-S-Q-S-F-S-K-I-H-Q-Q-V-I-Y-H-I-E-R-K-L-G-G-T-H-S-A


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-G-K-D-R-N-L-S-L-N-S-P-E-S-I-Q-S-V-I-G-D-T-D-I-K-I-A-V-I-A-A-M-W-H-E-K-I-V-R-G-L-I-D-G-A-T-R-E-I-V-S-S-G-S-H-A-E-L-F-R-V-P-G-S-V-E-L-V-L-A-C-K-K-L-L-K-T-F-D-A-A-V-A-L-G-V-I-L-R-G-E-T-D-H-N-T-H-I-A-R-L-V-L-S-G-I-T-D-V-M-L-A-L-E-K-P-I-G-I-G-V-L-T-I-D-T-E-Q-Q-G-L-D-R-S-S-G-D-Y-N-A-G-V-N-A-A-R-A-V-I-R-M-V-R-L-F-R


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-P-V-V-R-R-E-I-P-E-D-P-V-Y-S-S-R-V-V-S-Q-L-I-G-R-V-L-L-S-G-K-K-S-L-A-Q-R-I-V-Y-S-A-L-D-K-V-S-M-K-A-S-E-D-P-V-S-V-L-R-K-A-L-D-N-V-R-P-S-L-E-V-R-S-R-R-V-G-G-S-T-Y-Q-V-P-V-P-V-R-S-H-R-A-D-A-L-A-I-R-W-L-T-V-Y-S-R-A-R-R-E-K-S-M-V-D-R-L-A-S-E-I-L-D-A-S-N-G-V-G-A-T-V-K-C-K-E-D-T-H-R-M-A-E-S-N-R-A-F-A-H-Y-R-W


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-V-Y-P-V-V-E-A-E-S-R-V-G-F-G-K-G-F-A-R-R-A-R-A-A-G-K-I-P-A-V-A-Y-G-L-K-R-A-P-E-H-V-L-L-P-A-A-Q-M-S-L-I-M-R-R-A-N-A-L-L-Q-L-K-I-D-A-R-E-S-L-V-L-I-K-Q-V-Q-R-D-R-I-R-N-I-I-E-H-L-D-M-L-F-V-N-E-D-D-A-V-T-I-R-V-P-L-R-F-V-G-Q-S-Y-A-G-T-V-T-S-V-E-N-Y-S-V-A-V-T-L-Q-V-S-Q-I-P-E-A-L-V-V-D-V-S-G-L-Q-A-G-R-R-I-F-A-S-D-I-A-L-P-D-G-A-L-L-V-S-P-P-R-L-L-I-A-K-V-D-P-V-R-R-A-T-Q-E-P-P-P-D


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-C-V-Y-I-V-A-G-L-G-N-P-G-P-S-Y-D-K-T-R-H-N-V-G-Q-M-V-L-D-I-L-S-G-G-A-R-F-R-R-H-K-T-N-N-F-Y-L-S-L-G-D-I-L-L-V-K-P-D-A-Y-M-N-L-S-G-P-V-I-A-S-L-M-K-F-H-S-V-S-D-L-L-V-L-H-D-D-I-D-L-P-L-G-T-L-R-F-K-Q-G-G-G-T-A-G-H-R-G-L-R-S-I-S-D-C-L-G-S-D-Y-A-R-L-R-V-G-I-G-R-P-E-N-N-Q-S-I-E-D-F-V-L-S-N-F-S-P-V-Q-T-D-I-I-S-R-T-I-Q-L-A-A-E-A-V-L-H-L-R-D-N-G-F-V-G-V-K-Q-F-I-A-Q-T-K-S-P-S-R-T


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-V-R-V-A-R-S-V-N-A-R-K-K-R-R-S-I-L-A-A-A-K-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-V-L-R-S-L-V-Y-A-Y-R-D-R-R-K-R-K-S-S-F-R-K-L-W-I-I-R-I-N-A-A-A-R-M-E-G-V-T-Y-N-R-F-L-Q-G-L-K-L-A-N-I-E-L-D-R-R-S-L-A-H-L-A-V-H-N-P-D-T-F-S-A-L-V-G-V-A-K-D-S-L-K-N-A-P-D-P-V-A-A-P-R-L-R-G-T-S-S-R-T


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-G-L-L-Y-L-Q-N-S-S-G-Y-N-D-C-Y-F-K-T-E-S-L-V-D-F-L-Y-R-T-L-F-I-D-K-G-S-Y-L-G-V-S-F-I-T-A-A-E-M-R-D-L-K-I-K-H-F-G-V-N-E-D-S-D-V-L-S-F-P-I-D-E-I-A-P-G-S-E-N-S-L-V-Y-G-V-L-G-D-I-V-V-C-P-E-T-V-M-R-Q-A-V-R-H-P-F-E-H-E-I-Y-L-L-V-V-H-G-F-L-H-L-L-G-F-D-H-S-D-A-P-S-K-K-E-M-F-S-L-Q-A-K-L-I-E-D-F-F-A-L-E-N-L-G-T-P-S-E-E-I-T-I-T-P-D-L-R-P-S-L-G-R-I


### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-Q-L-F-D-L-W-T-D-L-L-D-L-L-T-I-V-A-G-P-T-A-V-G-K-G-T-V-I-S-H-L-R-K-C-H-P-Q-V-K-V-S-I-S-A-T-T-R-E-P-R-D-S-E-R-D-G-I-D-Y-Y-F-V-T-D-E-V-F-D-C-M-V-R-S-G-Q-M-L-E-W-A-T-V-H-G-L-H-K-Y-G-T-P-K-E-E-V-E-R-L-L-H-T-G-Q-P-V-I-L-E-I-D-L-Q-G-M-R-K-V-R-K-I-L-P-A-V-R-T-V-I-L-L-P-P-A-W-D-D-L-I-C-R-I-K-R-R-G-S-E-S-Q-D-E-I-D-A-R-L-A-T-A-K-K-E-L-E-A-I-G-E-F-D-Y-K-I-V-N-A-D-V-E-I-A-A-N-E-L-W-L-A-M-N-R-V


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-V-K-S-V-A-D-R-F-F-L-G-L-D-F-G-S-T-R-I-G-V-A-R-N-C-G-S-L-A-V-P-V-G-V-L-P-R-A-S-C-A-E-I-L-G-Y-I-S-R-Y-S-I-D-E-V-V-I-G-L-P-L-T-L-A-G-K-E-K-Q-S-A-R-L-A-K-E-F-S-R-F-L-V-S-S-G-V-Q-V-R-F-F-D-E-R-F-T-T-V-I-A-T-Q-K-F-Y-S-L-G-K-G-V-K-Q-I-R-K-C-V-D-A-A-A-A-T-V-M-L-Q-L-F-L-D-M-E-V-K-V-D-P-L-E-R-K-P


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-C-V-A-P-T-P-S-H-L-V-W-V-D-C-E-M-T-G-L-N-P-E-R-D-E-L-L-E-V-A-V-I-V-T-D-K-D-L-L-P-L-D-E-G-V-N-V-V-V-S-P-S-S-E-A-L-G-A-M-D-N-Y-V-A-R-M-H-R-V-S-G-L-L-D-E-L-S-N-G-V-P-V-S-E-A-Q-A-M-V-K-E-Y-I-T-K-H-I-K-T-G-G-I-M-S-G-N-S-I-A-T-D-R-L-F-I-T-R-Y-M-P-D-V-H-A-I-L-H-Y-R-M-I-D-V-S-S-I-K-E-L-A-V-R-W-A-P-E-I-Y-S-G-A-P-N-K-K-G-G-H-R-A-M-A-D-V-L-E-S-I-A-E-L-A-Y-Y-R-E-H-F-L-T-G-T-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-R-K-L-D-M-D-K-G-A-I-I-S-E-Y-G-L-S-K-G-D-T-G-S-P-E-V-Q-I-A-L-L-T-A-R-I-A-R-L-T-Q-H-L-K-E-H-S-F-D-H-H-S-R-R-G-L-M-L-M-V-G-R-R-R-R-L-L-S-Y-L-H-G-V-D-V-S-R-Y-R-A-I-L-S-N-L-G-L-R-R


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-K-F-A-Q-P-H-N-P-L-L-P-S-V-P-D-I-V-F-S-A-I-V-L-A-I-V-L-P-F-F-W-W-F-V-I-P-R-I-S-K-L-L-S-D-R-S-S-L-I-E-G-K-I-S-E-A-A-S-A-H-A-R-A-L-E-T-L-E-L-R-K-Q-Q-L-D-E-A-K-S-E-A-S-Q-I-R-Q-E-A-R-D-D-A-Q-L-I-L-Q-Q-A-R-E-T-A-D-E-T-A-E-R-V-M-L-H-A-R-E-Q-I-Q-A-E-K-A-A-A-L-L-S-L-R-S-E-I-A-T-L-A-L-A-A-A-G-K-A-V-S-E-K-L-D-D-D-K-K-S-R-E-L-V-S-A-S-I-A-K-M-A-E-D-A-G


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-G-I-M-C-S-G-D-V-S-E-R-M-N-K-T-I-E-L-L-K-E-Q-F-L-S-I-H-S-G-R-V-N-S-G-Q-F-E-K-V-M-V-D-C-E-G-A-S-V-P-L-V-S-L-A-S-I-R-V-L-N-A-N-T-I-V-V-T-P-Y-D-S-A-L-L-S-Q-I-D-R-A-L-R-N-V-P-N-I-G-T-P-G-N-D-G-E-C-I-K-I-V-M-P-Q-L-T-E-A-R-R-H-E-Y-V-K-Q-A-R-V-K-A-E-E-A-R-V-S-A-R-N-I-R-R-K-A-R-A-S-L-D-A-M-G-L-A-K-D-E-I-V-R-R-E-K-E-L-D-K-L-T-K-D-V-I-S-V-V-D-D-L-L-R-H-K-E-S-E-L-L-R-L


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-H-A-L-D-A-L-D-A-L-S-I-K-A-D-I-P-D-F-S-P-G-D-T-V-R-V-Y-V-N-I-T-E-G-D-R-S-R-V-Q-V-F-Q-G-V-V-I-A-R-R-G-F-G-V-R-Q-T-F-T-V-R-K-I-S-F-Q-V-G-V-E-R-I-F-P-L-H-S-P-S-I-N-R-I-E-V-V-T-K-G-S-V-R-R-A-K-L-Y-Y-I-R-K-L-R-G-K-K-A-K-V-K-Q-K-R-E-L


### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-G-G-T-F-D-P-I-H-H-G-H-L-V-V-A-S-E-V-A-S-R-F-C-L-D-E-V-I-F-V-P-T-G-R-P-P-H-K-K-E-V-S-D-P-W-H-R-Y-L-M-A-V-I-A-T-A-S-N-Q-R-F-S-V-S-K-I-D-I-E-R-T-G-P-T-F-T-V-D-T-L-R-E-L-R-E-Q-L-Q-S-S-D-L-F-F-I-T-G-T-D-A-L-A-R-I-F-S-W-K-D-A-D-T-L-W-S-L-A-H-F-V-A-V-S-R-P-G-H-E-V-V-D-I-P-N-D-R-I-S-F-L-E-V-P-A-M-A-I-S-S-S-N-C-R-E-R-V-R-S-G-L-P-I-W-Y-L-V-P-E-G-V-V-Q-Y-I-A-K-H-G-L-Y-R-S-L-Y-G


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-V-K-A-S-G-F-Q-R-L-V-E-V-G-S-V-I-S-I-D-P-T-N-V-D-S-G-G-F-V-H-L-P-V-L-L-L-V-D-G-A-E-V-V-S-D-P-D-K-L-R-L-A-R-V-S-A-K-F-L-R-K-L-R-G-P-K-V-R-I-H-K-F-K-N-K-T-G-Y-H-K-R-Q-G-H-R-Q-G-V-Y-V-F-S-V-T-S-I-E-R-G-D


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-S-E-T-K-Q-T-V-F-D-R-L-L-Q-E-R-I-V-W-L-G-E-A-I-D-D-K-L-A-N-E-I-C-A-K-I-L-L-L-N-A-D-D-P-K-E-D-I-F-L-Y-I-N-S-P-G-G-S-I-T-A-G-M-A-I-Y-D-T-M-Q-F-V-S-N-D-I-V-T-V-G-I-G-M-A-A-S-M-G-Q-V-L-L-T-S-G-T-Q-N-K-R-Y-I-M-P-N-A-R-V-L-L-H-Q-P-L-A-G-F-G-G-T-A-S-D-I-Q-T-Q-A-K-L-I-L-D-M-K-Y-R-L-S-Q-I-T-A-S-R-T-G-K-T-V-E-Q-I-M-E-D-G-D-R-D-H-W-F-T-A-E-E-A-L-E-Y-G-F-V-D-H-I-R-T-E


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-V-E-V-L-F-K-G-G-Y-T-P-Q-R-A-F-D-G-D-A-G-F-D-L-Q-S-S-H-T-A-V-I-Q-P-R-C-R-Q-V-V-K-T-G-I-A-I-A-L-P-D-G-Y-A-G-F-I-M-P-R-S-G-L-A-S-E-N-G-I-T-L-V-N-S-P-G-V-I-D-A-G-Y-R-G-E-I-S-V-V-L-I-N-T-D-L-H-Q-A-F-H-I-S-Q-G-D-R-I-A-Q-L-V-I-M-P-V-C-H-A-S-F-I-E-V-D-T-L-P-G-S-A-R-G-I-S-A-F-G-S-S-G-R-H-D-T-R-G


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-G-G-L-K-K-A-M-V-Y-L-G-L-A-E-D-N-Q-E-L-H-S-A-P-S-G-M-S-H-L-R-R-V-P-H-P-K-Q-Q-M-S-E-I-F-T-F-H-P-K-K-Y-S-E-V-S-G-I-V-E-R-F-R-Q-N-I-P-V-I-I-D-M-S-Q-L-S-D-T-D-A-R-R-M-I-D-F-A-S-G-L-S-Q-G-L-V-G-K-I-E-R-V-V-G-K-V-F-L-L-S-P-E-H-I-S-I-S-T-E-S-K-K-E-E


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-K-D-G-V-I-E-L-E-G-S-V-L-E-A-L-P-N-A-T-F-R-V-E-L-S-N-G-H-K-V-L-A-H-I-S-G-R-M-R-Q-H-Y-I-R-I-L-P-E-D-R-V-V-V-E-L-S-P-Y-D-L-A-R-G-R-I-V-Y-R-Y-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-I-K-L-H-H-L-R-P-A-P-G-S-R-R-A-R-I-R-V-G-R-G-E-G-S-K-G-K-T-A-G-R-G-T-K-G-T-K-A-R-A-P-V-R-P-G-F-A-G-G-Q-I-P-L-H-M-S-I-P-K-L-K-G-F-K-N-H-K-K-V-E-Y-S-V-I-S-I-K-R-L-C-E-A-Y-P-S-G-G-V-V-T-R-D-N-V-M-S-V-I-G-K-K-R-G-F-V-K-L-L-S-D-G-E-V-T-V-K-F-D-I-T-V-D-K-A-S-A-A-A-V-E-K-I-T-S-A-A-G-T-V-T-Q-A-R


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-L-T-S-R-A-S-A-R-K-R-R-H-V-R-L-R-K-K-I-S-G-T-C-D-R-P-R-L-S-V-T-R-S-N-R-H-V-F-V-Q-A-V-D-D-I-S-G-K-T-L-V-S-A-S-T-M-E-K-D-I-R-A-L-E-L-G-K-T-E-R-A-L-A-V-G-K-L-V-A-Q-R-A-L-A-V-G-V-K-S-A-V-F-D-R-G-G-C-K-Y-T-G-R-V-A-A-V-A-E-G-A-R-E-A-G-L-Q-T


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-L-P-I-E-I-P-V-G-V-E-V-C-V-N-G-R-T-V-S-I-T-G-P-K-G-S-L-Y-L-D-I-A-E-Q-I-G-V-S-V-S-D-G-K-V-L-V-S-R-S-D-D-S-R-T-A-R-A-L-H-G-L-T-R-A-L-I-A-N-N-V-H-G-V-L-H-G-Y-T-K-T-L-E-I-V-G-T-G-Y-R-V-S-K-K-G-E-N-L-E-L-A-L-G-F-S-H-P-V-F-V-D-P-V-P-G-V-S-F-G-V-E-G-N-S-K-I-I-V-S-G-I-D-K-Q-A-V-G-E-A-A-A-S-I-R-K-L-S-K-P-E-P-Y-K-G-K-G-I-R-Y-S-D-E-I-V-R-R-K-V-G-K-A-G-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-L-S-D-M-F-S-R-I-R-N-A-N-Q-V-L-H-K-K-V-T-V-P-S-S-R-L-K-V-S-I-A-D-L-L-K-R-E-G-Y-I-L-D-Y-S-V-I-D-E-H-P-G-Q-L-L-V-I-E-L-K-Y-G-P-D-K-S-R-A-L-V-G-L-K-R-V-S-K-P-G-L-R-V-Y-A-K-S-S-N-L-P-E-V-F-G-G-L-G-I-A-I-L-S-T-S-S-G-L-L-T-C-S-Q-A-R-K-K-G-V-G-G-E-V-L-A-Y-A-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-C-Y-T-P-R-L-L-T-R-Y-R-E-E-I-V-P-V-L-M-S-R-F-D-I-N-N-V-H-Q-V-P-S-I-T-K-I-V-V-N-S-G-V-G-D-A-A-R-D-S-K-I-I-E-G-A-V-S-D-I-T-L-I-T-G-Q-K-P-R-I-N-R-A-K-Q-S-I-A-K-F-K-L-R-E-G-Q-A-V-G-V-T-A-T-L-R-G-R-R-M-W-E-F-L-D-R-L-L-T-L-A-L-P-R-I-R-D-F-R-G-I-S-D-K-Q-F-D-G-H-G-N-Y-T-F-G-L-S-E-Q-G-I-F-H-E-I-D-Q-D-K-I-D-R-V-R-G-M-D-I-T-V-V-T-T-S-S-S-D-D-M-A-R-A-L-L-G-E-L-G-F-P-F-K-K


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-S-V-K-I-R-K-G-D-L-V-Q-V-I-T-G-S-K-T-G-G-K-K-G-K-Q-G-R-V-L-A-V-S-G-D-R-V-W-V-E-G-V-N-L-T-T-R-H-R-K-R-V-T-N-D-K-G-T-S-S-G-G-L-E-K-R-E-S-P-M-H-I-S-N-V-A-L-V-D-P-E-T-G-A-P-T-K-V-G-F-L-V-K-T-S-G-D-K-T-V-R-V-R-F-A-K-K-S-G-K-E-L-T


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-T-G-A-K-S-L-S-V-I-R-V-L-G-G-S-N-R-R-F-G-S-L-G-D-V-V-V-A-S-V-K-D-A-V-P-G-S-S-A-V-K-K-G-D-V-V-K-A-V-I-V-R-S-T-K-E-V-R-R-T-D-G-S-Y-I-R-F-D-D-N-A-A-V-I-L-R-P-D-N-D-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-D-R-K-F-T-R-I-I-S-L-A-P-E-V-V


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-Q-Q-R-G-Y-R-K-S-R-R-G-Y-V-T-S-N-S-M-D-K-T-I-V-V-K-I-E-D-R-V-K-H-A-L-Y-G-K-V-I-R-K-T-S-K-V-K-A-H-D-Q-G-S-I-A-G-V-G-D-L-V-L-I-S-E-T-R-P-I-S-A-T-K-R-W-R-L-V-Q-I-L-E-K-A-K


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-M-L-I-P-K-K-V-K-F-R-K-Q-H-R-P-N-R-K-G-M-S-G-C-G-T-R-I-V-F-G-D-Y-G-I-Q-A-L-S-R-A-Y-V-T-N-R-Q-V-E-S-A-R-I-A-M-T-R-H-I-R-R-G-G-R-V-W-I-N-I-Y-P-D-R-P-L-T-K-K-P-A-E-T-R-M-G-S-G-K-G-S-P-E-Y-W-V-A-N-I-R-P-G-R-I-M-F-E-V-S-G-V-S-E-S-L-A-K-E-A-L-M-R-A-I-H-K-L-P-L-R-A-R-I-V-E-R-Q-E-F-D-D-A-G-L


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-E-E-K-D-T-P-L-E-A-F-A-S-L-K-H-S-G-V-T-P-Q-K-V-R-R-I-V-D-L-I-R-G-R-S-V-D-E-A-L-A-I-L-R-F-S-P-H-S-A-S-G-I-L-Y-K-L-I-V-S-A-Q-A-N-Y-A-N-L-L-G-R-D-D-D-L-F-V-S-S-V-Y-V-D-E-G-K-T-Y-K-R-G-R-P-R-A-R-G-S-S-S-R-I-L-K-R-G-S-H-V-T-V-T-L-S-K-E-V-R


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-V-D-M-H-L-L-K-K-V-R-A-G-N-E-S-K-D-R-N-M-I-K-T-W-S-R-R-S-M-I-I-P-E-M-L-G-H-T-I-A-V-H-D-G-R-R-H-I-P-V-F-I-T-E-S-M-V-G-H-K-L-G-E-F-A-P-T-R-T-Y-R-G-H-V-K-D-D-R-K-A-R-R-R


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-E-E-Q-K-I-R-I-R-L-K-S-Y-S-H-E-I-I-D-V-S-A-K-K-I-V-D-T-V-T-R-A-G-A-T-I-V-G-P-V-P-L-P-T-K-K-S-V-V-C-V-I-R-S-P-H-R-H-K-D-S-R-E-H-F-E-M-R-T-H-K-R-L-I-N-V-V-D-L-T-P-R-A-V-D-A-L-M-R-L-D-L-S-S-E-V-N-V-E-I-K-L


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-S-K-L-S-K-I-V-K-N-E-K-R-K-V-I-V-A-R-Y-A-A-R-R-Q-E-L-K-R-I-I-A-A-P-G-T-A-P-E-R-R-D-E-A-Q-A-A-L-Q-K-L-P-R-D-A-S-P-V-R-V-R-S-R-D-V-V-D-G-R-P-R-G-I-L-S-R-F-G-V-S-R-I-R-F-R-E-M-A-H-R-G-E-L-P-G-I-T-K-S-S-W


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-L-G-S-P-L-R-E-Y-E-L-L-V-S-L-G-S-E-F-E-P-E-A-E-S-R-V-R-S-L-F-T-P-V-E-P-E-G-V-T-V-K-H-L-D-V-L-G-V-R-K-F-A-Y-E-I-K-G-R-N-D-G-V-C-V-V-V-R-L-L-A-N-A-G-S-I-A-E-I-G-R-Q-M-R-L-T-E-D-V-I-R-T-K-L-L-R-V-G-R-K


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-G-Y-R-A-K-G-R-R-Q-P-K-A-D-S-V-V-A-P-P-K-R-V-S-I-K-G-L-D-Y-K-D-L-A-S-L-K-R-F-L-S-D-R-G-K-I-R-A-R-R-V-T-G-A-S-I-Q-Q-Q-R-Q-I-A-K-A-I-K-N-A-R-E-M-G-V-I-P-F-K-S-G-V-S-R


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-T-R-V-I-L-V-Q-D-V-N-G-L-G-S-V-G-D-V-V-E-V-K-A-G-Y-S-R-N-Y-L-V-P-K-G-M-A-V-R-W-T-E-G-A-Q-K-H-I-G-D-I-S-A-A-R-R-A-R-E-A-A-A-L-Q-E-A-R-D-I-A-N-T-L-T-K-E-A-V-T-R-E-L-R-L-A-A-N-A-G-E-D-G-R-L-F-G-S-V-T-A-A-N-I-A-K-V-L-S-S-A-S-G-H-K-I-D-R-G-K-I-E-I-D-S-P-I-K-T-L-G-E-H-T-V-K-V-K-L-H-P-N-V-K-V-D-I-N-V-V-V-Y-A-E


### FUNCTION Involved in the degradation and recycling of damaged RNA It is itself a target for degradation by the ATP-dependent protease Lon ### SEQUENCE -M-T-D-T-H-S-I-A-Q-P-L-E-A-E-V-S-P-A-N-N-R-Q-L-T-V-S-Y-A-S-R-Y-P-D-Y-S-R-I-P-A-I-T-L-K-G-Q-W-L-E-A-A-G-F-A-T-G-T-A-V-D-V-K-V-M-E-G-C-I-V-L-T-A-Q-P-A-A-A-E-E-S-E-L-M-Q-S-L-R-K-V-C-K-L-S-A-R-K-Q-R-Q-V-Q-E-F-I-G-V-I-T-G-K-Q-K-V-A


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-S-A-N-E-N-N-L-I-W-I-D-L-E-M-T-G-L-D-P-E-R-D-R-I-I-E-I-A-T-L-V-T-D-A-N-L-N-I-L-A-E-G-P-T-I-A-V-H-Q-S-D-E-Q-L-A-L-M-D-D-W-N-V-R-T-H-T-A-S-G-L-V-E-R-V-K-A-S-T-M-G-D-R-E-A-E-L-A-T-L-E-F-L-K-Q-W-V-P-A-G-K-S-P-I-C-G-N-S-I-G-Q-D-R-R-F-L-F-K-Y-M-P-E-L-E-V-Y-F-H-Y-R-Y-L-D-V-S-T-L-K-E-L-A-R-R-W-K-P-E-I-L-D-G-F-T-K-Q-G-T-H-Q-A-M-D-D-I-R-E-S-V-A-E-L-A-Y-Y-R-E-H-F-I-K-L


### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-T-H-D-N-K-L-Q-V-E-A-I-K-R-G-T-V-I-D-H-I-P-A-Q-I-G-F-K-L-L-S-L-F-K-L-T-E-T-D-Q-R-I-T-I-G-L-N-L-P-S-G-E-M-G-R-K-D-L-I-K-I-E-N-T-F-L-S-E-E-Q-V-D-Q-L-A-L-Y-A-P-Q-A-T-V-N-R-I-D-N-Y-E-V-V-G-K-S-R-P-S-L-P-E-R-I-D-N-V-L-V-C-P-N-S-N-C-I-S-H-A-E-P-V-S-S-S-F-A-V-R-K-R-A-N-D-I-A-L-K-C-K-Y-C-E-K-E-F-S-H-N-V-V-L-A-N


### FUNCTION Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate  for the ubiquinone pathway ### SEQUENCE -M-S-H-P-A-L-T-Q-L-R-A-L-R-Y-F-K-E-I-P-A-L-D-P-Q-L-L-D-W-L-L-L-E-D-S-M-T-K-R-F-E-Q-Q-G-K-T-V-S-V-T-M-I-R-E-G-F-V-E-Q-N-E-I-P-E-E-L-P-L-L-P-K-E-S-R-Y-W-L-R-E-I-L-L-C-A-D-G-E-P-W-L-A-G-R-T-V-V-P-V-S-T-L-S-G-P-E-L-A-L-Q-K-L-G-K-T-P-L-G-R-Y-L-F-T-S-S-T-L-T-R-D-F-I-E-I-G-R-D-A-G-L-W-G-R-R-S-R-L-R-L-S-G-K-P-L-L-L-T-E-L-F-L-P-A-S-P-L-Y


### FUNCTION Involved in iron-sulfur  cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-N-D-S-E-F-H-R-L-A-D-Q-L-W-L-T-I-E-E-R-L-D-D-R-D-G-D-S-D-I-D-C-E-I-N-G-G-V-L-T-I-T-F-E-N-G-S-K-I-I-I-N-R-Q-E-P-L-H-Q-V-W-L-A-T-K-Q-G-G-Y-H-F-D-L-K-G-D-E-W-I-C-D-R-S-G-E-T-F-W-D-L-L-E-Q-A-A-T-Q-Q-A-G-E-T-V-S-F-R


### FUNCTION May act as a transcriptional regulator of dctA ### SEQUENCE -M-F-L-I-I-T-R-D-T-M-F-F-T-A-M-K-N-I-L-S-K-G-N-V-V-H-I-Q-N-E-E-E-I-D-V-M-L-H-Q-N-A-F-V-I-I-D-T-L-M-N-N-V-F-H-S-N-F-L-T-Q-I-E-R-L-K-P-V-H-V-I-V-F-S-P-F-N-I-K-R-C-L-G-K-V-P-V-T-F-V-P-R-T-I-T-I-I-D-F-V-A-L-I-N-G-S-Y-C-S-V-P-E-A-N-V-S-L-S-R-K-Q-H-Q-V-L-S-C-I-A-N-Q-M-T-T-E-D-I-L-E-K-L-K-I-S-L-K-T-F-Y-C-H-K-H-N-I-M-M-I-L-N-L-K-R-I-N-E-L-V-R-H-Q-H-I-D-Y-L-V


### FUNCTION May function as a transcriptional regulator that controls feoABC expression ### SEQUENCE -M-A-S-L-I-Q-V-R-D-L-L-A-L-R-G-R-M-E-A-T-Q-I-S-Q-T-L-N-T-P-Q-P-M-I-N-A-M-L-Q-Q-L-E-S-M-G-K-A-V-R-I-Q-E-E-P-D-G-C-L-S-G-S-C-K-S-C-P-E-G-K-A-C-L-R-E-W-W-A-L-R


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine  at tRNA wobble positions Accepts sulfur from TusA and transfers it in turn to TusE ### SEQUENCE -M-R-F-A-I-V-V-T-G-P-A-Y-G-T-Q-Q-A-S-S-A-F-Q-F-A-Q-A-L-I-A-E-G-H-K-L-S-S-V-F-F-Y-R-E-G-V-Y-N-A-N-Q-L-T-S-P-A-S-D-E-F-D-L-V-R-G-W-Q-Q-L-N-A-Q-H-G-V-A-L-N-I-C-V-A-A-A-L-R-R-G-I-V-D-E-T-E-A-G-R-L-G-L-A-S-S-N-L-Q-P-G-F-T-L-S-G-L-G-A-L-A-E-A-S-L-T-C-D-R-V-V-Q-F


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine  at tRNA wobble positions ### SEQUENCE -M-K-R-I-A-F-V-F-S-T-A-P-H-G-T-A-A-G-R-E-G-L-D-A-L-L-A-T-S-A-L-T-D-D-L-A-V-F-F-I-A-D-G-V-F-Q-L-L-S-G-Q-K-P-D-A-V-L-A-R-D-Y-I-A-T-F-K-L-L-S-L-Y-D-I-E-Q-C-W-V-C-A-A-S-L-R-E-R-G-L-D-P-Q-T-P-F-V-V-E-A-T-P-L-E-A-D-A-L-R-R-E-L-A-N-Y-D-V-I-L-R-F


### FUNCTION Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine  at tRNA wobble positions ### SEQUENCE -M-L-H-T-L-H-R-S-P-W-L-T-D-F-A-A-L-L-R-L-L-S-E-G-D-E-L-L-L-L-Q-D-G-V-T-A-A-V-D-G-N-R-Y-L-E-S-L-R-N-A-P-I-K-V-Y-A-L-N-E-D-L-I-A-R-G-L-T-G-Q-I-L-N-D-I-I-P-I-D-Y-T-D-F-V-R-L-T-V-K-H-S-S-Q-M-A-W


### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-T-S-L-Y-L-A-S-G-S-P-R-R-Q-E-L-L-A-Q-L-G-V-T-F-E-R-I-V-T-G-I-E-E-Q-R-Q-P-Q-E-S-A-Q-Q-Y-V-V-R-L-A-R-E-K-A-Q-A-G-V-A-Q-T-A-Q-D-L-P-V-L-G-A-D-I-I-V-I-L-N-G-E-V-L-E-K-P-R-D-A-E-H-A-A-Q-M-L-R-K-L-S-G-Q-T-H-Q-V-M-T-A-V-A-L-A-D-S-Q-H-I-L-D-C-L-V-V-T-D-V-T-F-R-T-L-T-D-E-D-I-A-G-Y-V-A-S-G-E-P-L-D-K-A-G-A-Y-G-I-Q-G-L-G-G-C-F-V-R-K-I-N-G-S-Y-H-A-V-V-G-L-P-L-V-E-T-Y-E-L-L-S-N-F-N-A-L-R-E-K-R-D-K-H-D-G


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-G-T-L-L-A-F-D-F-G-T-K-S-I-G-V-A-V-G-Q-R-I-T-G-T-A-R-P-L-P-A-I-K-A-Q-D-G-T-P-D-W-N-L-I-E-R-L-L-K-E-W-Q-P-D-E-I-I-V-G-L-P-L-N-M-D-G-T-E-Q-P-L-T-A-R-A-R-K-F-A-N-R-I-H-G-R-F-G-V-E-V-K-L-H-D-E-R-L-S-T-V-E-A-R-S-G-L-F-E-Q-G-G-Y-R-A-L-N-K-G-K-V-D-S-A-S-A-V-I-I-L-E-S-Y-F-E-Q-G-Y


### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase  of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-D-I-N-N-K-A-R-I-H-W-A-C-R-R-G-M-R-E-L-D-I-S-I-M-P-F-F-E-H-E-Y-D-S-L-S-D-D-E-K-R-I-F-I-R-L-L-E-C-D-D-P-D-L-F-N-W-L-M-N-H-G-K-P-A-D-A-E-L-E-I-M-V-R-L-I-Q-T-R-N-R-E-R-G-P-V-A-I


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-G-K-L-T-L-L-L-L-A-I-L-V-W-L-Q-Y-S-L-W-F-G-K-N-G-I-H-D-Y-T-R-V-N-D-D-V-A-A-L-Q-A-T-N-A-K-L-K-A-R-N-D-Q-L-F-A-E-I-D-D-L-N-G-G-Q-E-A-L-E-E-R-A-R-N-E-L-S-M-T-R-P-G-E-T-F-Y-R-L-V-P-D-A-S-K-R-A-Q-S-A-G-Q-N-N-R


### FUNCTION Has NMN aminohydrolase activity, not active on other substrates ### SEQUENCE -M-T-D-S-E-L-M-Q-L-S-E-Q-V-G-Q-A-L-K-A-R-G-A-T-V-T-T-A-E-S-C-T-G-G-W-V-A-K-V-I-T-D-I-A-G-S-S-A-W-F-E-R-G-F-V-T-Y-S-N-E-A-K-A-Q-M-I-G-V-R-E-E-T-L-A-Q-H-G-A-V-S-E-P-V-V-V-E-M-A-I-G-A-L-K-A-A-R-A-D-Y-A-V-S-I-S-G-I-A-G-P-D-G-G-S-E-E-K-P-V-G-T-V-W-F-A-F-A-T-A-R-G-E-G-I-T-W-R-E-C-F-S-G-D-R-D-A-V-R-R-Q-A-T-A-Y-A-L-Q-T-L-W-Q-Q-F-L-Q-N-T


### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-T-V-D-H-T-R-M-E-A-P-A-V-R-V-A-K-T-M-N-T-P-H-G-D-A-I-T-V-F-D-L-R-F-C-V-P-N-K-E-V-M-P-E-R-G-I-H-T-L-E-H-L-F-A-G-F-M-R-N-H-L-N-G-N-G-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-T-P-D-E-Q-R-V-A-D-A-W-K-A-A-M-E-D-V-L-K-V-Q-D-Q-N-Q-I-P-E-L-N-V-Y-Q-C-G-T-Y-Q-M-H-S-L-Q-E-A-Q-D-I-A-R-S-I-L-E-R-E-V-R-I-N-S-N-E-E-L-A-L-P-K-E-K-L-Q-E-L-H-I


### FUNCTION Acts as a radical domain for damaged PFL and possibly other radical proteins ### SEQUENCE -M-I-T-G-I-Q-I-T-K-A-A-N-A-D-L-L-N-S-F-W-L-L-D-S-E-K-G-E-A-R-C-I-V-A-K-A-G-Y-A-E-D-E-V-V-A-V-S-K-L-G-D-I-E-Y-R-E-V-P-V-E-V-K-P-E-V-R-V-E-G-G-Q-H-L-N-V-N-V-L-R-R-E-T-L-E-D-A-V-K-H-P-E-K-Y-P-Q-L-T-I-R-V-S-G-Y-A-V-R-F-N-S-L-T-P-E-Q-Q-R-D-V-I-A-R-T-F-T-E-S-L


### FUNCTION Exporter of O-acetylserine  and cysteine ### SEQUENCE -M-T-P-I-L-L-S-A-F-W-T-Y-T-L-I-T-A-M-T-P-G-P-N-N-I-L-A-L-S-S-A-T-S-H-G-F-R-Q-S-T-R-V-L-A-G-M-S-L-G-F-L-I-V-M-L-L-C-A-G-I-S-F-S-L-A-V-I-D-P-A-A-V-H-L-L-S-W-A-G-A-A-Y-I-V-W-L-A-W-K-I-A-T-S-P-T-K-E-D-G-L-Q-A-K-P-I-S-F-W-A-S-F-A-L-Q-F-V-N-V-K-I-I-L-Y-G-V-T-A-L-S-T-F-V-L-P-Q-T-Q-A-L-S-W-V-V-G-V-S-V-L-L-A-M-I-G-T-F-G-N-V-C-W-A-L-A-G-H-L-F-Q-R-L-F-R-Q-Y-G-R-Q-L-N-I-V-L-A-L-L-L-V-Y-C-A-V-R-I-F-Y


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-L-G-L-G-T-D-I-V-E-I-A-R-I-E-A-V-I-A-R-S-G-E-R-L-A-R-R-V-L-S-D-N-E-W-A-I-W-K-T-H-H-Q-P-V-R-F-L-A-K-R-F-A-V-K-E-A-A-A-K-A-F-G-T-G-I-R-N-G-L-A-F-N-Q-F-E-V-F-N-D-E-L-G-K-P-R-L-R-L-W-G-E-A-L-K-L-A-E-K-L-G-V-V-N-M-H-V-T-L-A-D-E-R-H-Y-A-C-A-T-V-I-I-E-S


### FUNCTION Part of the multicomponent 3-phenylpropionate dioxygenase Converts 3-phenylpropionic acid , respectively ### SEQUENCE -M-S-A-Q-V-S-L-E-L-H-H-R-I-S-Q-F-L-F-H-E-A-S-L-L-D-D-W-K-F-R-D-W-L-A-Q-L-D-E-E-I-R-Y-T-M-R-T-T-V-N-A-Q-T-R-D-R-R-K-G-V-Q-P-P-T-T-W-I-F-N-D-T-K-D-Q-L-E-R-R-I-A-R-L-E-T-G-M-A-W-A-E-E-P-P-S-R-T-R-H-L-I-S-N-C-Q-V-S-E-T-D-I-P-N-V-F-A-V-R-V-N-Y-L-L-Y-R-A-Q-K-E-R-D-E-T-F-Y-V-G-T-R-F-D-K-V-R-R-L-E-D-D-N-W-R-L-L-E-R-D-I-V-L-D-Q-A-V-I-T-S-H-N-L-S-V-L-F


### FUNCTION Antitoxin component of a type II toxin-antitoxin ### SEQUENCE -M-R-T-I-S-Y-S-E-A-R-Q-N-L-S-A-T-M-M-K-A-V-E-D-H-A-P-I-L-I-T-R-Q-N-G-E-A-C-V-L-M-S-L-E-E-Y-N-S-L-E-E-T-A-Y-L-L-R-S-P-A-N-A-R-R-L-M-D-S-I-D-S-L-K-S-G-K-G-T-E-K-D-I-I-E-W-V-M-L-P-T-Y


### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane Required to maintain the reduced state of SoxR ### SEQUENCE -M-T-D-Y-L-L-L-F-V-G-T-V-L-V-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-K-K-L-E-T-A-M-G-M-G-L-A-T-T-F-V-M-T-L-T-S-I-C-A-W-L-I-D-T-W-I-L-I-P-L-N-L-I-Y-L-R-T-L-A-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-V-V-R-K-T-S-P-V-L-Y-R-L-L-G-I-F-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-I-N-L-G-H-N-F-L-Q-S-A-L-Y-G-F-S-A-A-V-G-F-S-L-V-M-V-L-F-A-A-I-R-E-R-L-A-V-A-D-V-P-A-P-F-R-G-N-A-I-A-L-I-T-A-G-L-M-S-L-A-F-M-G-F-S-G-L-V-K-L


### FUNCTION Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle Catalyzes the conversion of ### SEQUENCE -M-H-V-T-L-V-E-I-N-V-H-E-D-K-V-D-E-F-I-E-V-F-R-Q-N-H-L-G-S-V-Q-E-E-G-N-L-R-F-D-V-L-Q-D-P-E-V-N-S-R-F-Y-I-Y-E-A-Y-K-D-E-D-T-V-A-F-H-K-T-T-P-H-Y-K-T-C-V-A-K-L-E-S-L-M-T-G-P-R-K-K-R-L-F-N-G-L-M-P


### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation ### SEQUENCE -M-K-W-I-V-I-D-T-V-I-Q-P-S-C-G-I-S-F-S-V-I-W-S-K-I-K-L-I-I-W-Y-Q-S-D-A-F-L-P-P-E-S-I-F-T-L-T-H-T-G-I-M-L-N-N-K-V-L-P-V-T-I-Y-N-V-V-P-F-N-K-T-F-W-N-L-I-K-N-S-Q-E-C-P-T-N-T-D-N-V-L-N-E-C-F-N-N-R-C-T-L-Q-I-C-P-Y-G-L-K-Q-Q-S-P


### FUNCTION Probably mediates the hydrolysis of some nucleoside diphosphate derivatives ### SEQUENCE -M-E-Y-R-S-L-T-L-D-D-F-L-S-R-F-Q-L-L-R-P-Q-I-N-R-E-P-L-N-H-R-Q-A-A-V-L-I-P-I-V-R-R-P-Q-P-G-L-L-L-T-Q-R-S-I-H-L-R-K-H-A-G-Q-V-A-F-P-G-G-A-V-D-D-T-D-A-S-V-I-A-A-A-L-R-E-A-E-E-E-V-A-I-P-P-S-A-V-E-V-I-G-V-L-P-P-V-D-S-V-T-G-Y-Q-V-T-P-V-V-G-I-I-P-P-D-L-P-Y-R-A-S-E-D-E-V-S-A-V-F-E-M-P-L-A-Q-A-L-H-L-G-R-Y-H-P-L-D-I-Y-R-R-G-D-S-H-R-V-W-L-S-W-Y-E-Q-Y-F-V-W-G-M-T-A-G-I-I-R-E-L-A-L-Q-I-G-V-T-P


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-I-K-L-I-V-G-L-A-N-P-G-A-E-Y-A-A-T-R-H-N-A-G-A-W-F-V-D-L-L-A-E-R-L-R-A-P-L-R-E-E-A-K-F-F-G-Y-T-S-R-V-T-L-G-S-E-D-V-R-L-L-V-P-T-T-F-M-N-L-S-G-K-A-V-A-A-M-A-S-F-F-R-I-N-P-D-E-I-L-V-A-H-D-E-L-D-L-P-P-G-V-A-K-F-K-L-G-G-G-H-G-G-H-N-G-L-K-D-I-I-S-K-L-G-N-N-P-N-F-H-R-L-R-I-G-I-G-H-P-G-D-K-N-K-V-V-G-F-V-L-G-K-P-P-V-S-E-Q-K-L-I-D-E-A-I-D-E-A-A-R-C-T-E-M-W-F-T-D-G-L-T-K-A-T-N-R-L-H-A-F-K-A-Q


### FUNCTION Involved in pyrimidine catabolism Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions ### SEQUENCE -M-P-K-S-V-I-I-P-A-G-S-S-A-P-L-A-P-F-V-P-G-T-L-A-D-G-V-V-Y-V-S-G-T-L-A-F-D-Q-H-N-N-V-L-F-A-D-D-P-K-A-Q-T-R-H-V-L-E-T-I-R-K-V-I-E-T-A-G-G-T-M-A-D-V-T-F-N-S-I-F-I-T-D-W-K-N-Y-A-A-I-N-E-I-Y-A-E-F-F-P-G-D-K-P-A-R-F-Y-I-Q-C-G-L-V-K-P-D-A-L-V-E-I-A-T-I-A-H-I-A-K


### FUNCTION Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products Thus, can divert a surplus of harmful intermediates into relatively harmless products and pre-empt the damage these intermediates would otherwise do Helps maintain flavin levels May act on other substrates in vivo Has no activity against GTP, nucleoside monophosphates or ADP-ribose Is Required for swarming motility ### SEQUENCE -M-P-V-R-A-Q-R-I-Q-H-V-M-Q-D-T-I-I-N-F-Y-S-T-S-D-D-Y-G-D-F-S-N-F-A-A-R-P-I-K-V-D-G-N-T-W-P-T-S-E-H-Y-F-Q-A-Q-K-F-L-D-E-K-Y-R-E-E-I-R-R-V-S-S-P-M-V-A-A-R-M-G-R-N-R-S-K-P-L-R-K-N-W-E-S-V-K-E-Q-V-M-R-K-A-L-R-A-K-F-E-Q-H-A-E-L-R-V-L-L-L-A-T-A-P-A-K-L-V-E-H-T-E-N-D-A-Y-W-G-D-G-G-N-G-K-G-K-N-R-L-G-Y-L-L-M-E-L-R-E-Q-L-A-I-E-K


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-Q-L-L-L-A-V-F-I-G-G-G-T-G-S-V-A-R-W-L-L-S-M-R-F-N-P-L-H-Q-A-I-P-L-G-T-L-A-A-N-L-I-G-A-F-I-I-G-M-G-F-A-W-F-S-R-M-T-N-I-D-P-V-W-K-V-L-I-T-T-G-F-C-G-G-L-T-T-F-S-T-F-S-A-E-V-V-F-L-L-Q-E-G-R-F-G-W-A-L-L-N-V-F-V-N-L-L-G-S-F-A-M-T-A-L-A-F-W-L-F-S-A-S-T-V-H


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-A-T-A-Q-Q-L-E-Y-L-K-N-S-I-K-S-I-Q-D-Y-P-K-P-G-I-L-F-R-D-V-T-S-L-L-E-D-P-K-A-Y-A-L-S-I-D-L-L-V-E-R-Y-K-N-A-G-I-T-K-V-V-G-T-E-A-R-G-F-L-F-G-A-P-V-A-L-G-L-G-V-G-F-V-P-V-R-K-P-G-K-L-P-R-E-T-I-S-E-N-Y-D-L-E-Y-G-T-D-Q-L-E-I-H-V-D-A-I-K-P-G-D-K-V-L-V-V-D-D-L-L-A-T-G-G-T-I-E-A-T-V-K-L-I-R-R-L-G-G-E-V-A-D-A-A-F-I-I-N-L-F-D-L-G-G-E-Q-R-L-E-K-Q-G-I-T-S-Y-S-L-V-P-F-P-G-H


### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway ### SEQUENCE -M-K-N-L-I-A-E-L-L-F-K-L-A-Q-K-E-E-E-S-K-E-L-C-A-Q-V-E-A-L-E-I-I-V-T-A-M-L-R-N-M-A-Q-N-D-Q-Q-R-L-I-D-Q-V-E-G-A-L-Y-E-V-K-P-D-A-S-I-P-D-D-D-T-E-L-L-R-D-Y-V-K-K-L-L-K-H-P-C-Q


### FUNCTION Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall  gene cluster Acts by binding directly to DNA May also regulate the expression of genes outside the dcw cluster ### SEQUENCE -M-F-R-G-A-T-L-V-N-L-D-S-K-G-R-L-S-V-P-T-R-Y-R-E-Q-L-L-E-N-A-A-G-Q-M-V-C-T-I-D-I-H-H-P-C-L-L-L-Y-P-L-P-E-W-E-I-I-E-Q-K-L-S-R-L-L-S-M-N-P-V-E-R-R-V-Q-R-L-L-L-G-H-A-S-E-C-Q-M-D-G-A-G-R-L-L-I-A-P-V-L-R-Q-H-A-G-L-T-K-E-V-M-L-V-G-Q-F-N-K-F-E-L-W-D-E-T-T-W-H-Q-Q-V-K-E-D-I-D-A-E-Q-L-A-T-G-D-L-S-E-R-L-Q-D-L-S-L


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-K-S-N-E-T-E-R-M-E-E-S-E-E-T-H-S-S-D-I-R-S-A-S-E-S-D-H-A-S-G-S-D-H-T-E-S-A-D-E-I-P-T-A-D-A-E-Q-G-E-L-E-Q-L-E-K-L-K-D-D-L-A-R-E-R-A-A-F-H-N-F-R-M-A-R-A-K-Q-A-E-I-E-R-D-R-T-R-S-E-V-I-R-V-I-L-P-V-L-D-D-F-A-R-I-E-K-H-S-T-L-D-D-P-F-K-A-V-V-T-K-L-R-S-A-M-E-K-I-G-L-T-A-F-G-N-P-G-D-P-F-N-P-E-L-H-E-A-L-F-Q-N-P-S-P-D-V-Q-T-E-T-V-Q-D-V-I-E-A-G-Y-C-L-G-E-T-V-I-R-A-A-K-V-V-V-Q-V-P-N-G


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Y-V-R-I-V-Q-D-L-I-R-E-L-G-K-L-P-G-I-G-P-K-S-A-Q-R-I-T-F-F-I-L-Q-N-P-S-F-D-I-D-R-L-S-E-T-L-Q-S-V-R-K-Q-V-Q-F-C-K-V-C-G-N-F-S-E-E-D-E-C-V-I-C-S-D-P-R-R-D-R-G-V-I-C-V-V-E-E-P-K-D-V-V-A-I-E-K-T-R-E-F-S-G-L-Y-H-V-L-G-G-A-I-S-P-I-D-G-V-G-P-D-D-L-N-I-R-Q-L-L-Q-R-L-A-D-G-T-I-T-E-V-V-L-A-T-D-P-N-M-E-G-E-A-T-A-S-Y-I-A-R-V-I-S-A-M-R-I-R-V-S-K-L-A-S-G-L-P-V-G-S-D-L-E-Y-A-D-E-I-T-L-G-R-A-L-E-G-R-Q-Y-I-N


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-A-S-T-S-D-I-R-N-G-V-V-L-N-I-N-G-Q-L-N-T-V-I-E-F-Q-H-V-K-P-G-K-G-G-A-F-V-R-T-K-L-K-N-I-L-T-G-K-V-V-D-K-T-F-N-A-G-A-S-V-V-L-E-N-V-D-R-R-D-C-T-Y-L-Y-R-D-A-D-S-F-V-F-M-D-L-A-D-Y-D-Q-I-R-L-T-A-S-Q-V-A-S-A-A-N-Y-L-S-D-N-Q-K-V-V-I-A-T-H-N-N-A-P-L-Y-V-D-L-P-P-S-V-V-L-A-V-T-H-T-E-P-G-V-Q-A-D-R-S-T-G-G-T-K-P-A-T-L-E-T-G-Y-Q-I-Q-V-P-L-F-I-T-V-G-T-R-I-R-V-D-T-R-T-G-A-Y-I-G-K-A


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-L-S-R-E-K-V-L-E-S-I-A-Q-I-V-H-D-E-T-G-I-D-K-G-S-V-Q-L-D-K-A-F-V-D-D-L-D-I-D-S-I-S-M-M-T-I-V-V-N-A-E-E-K-Y-G-I-E-I-P-D-D-K-V-R-E-L-R-T-V-G-D-A-V-D-F-I-I-A-A-K-A


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-D-R-V-K-E-F-A-M-K-D-Q-I-R-A-H-R-M-A-G-R-I-R-H-L-I-S-R-Q-I-E-T-K-L-R-D-Q-L-G-L-V-T-I-T-E-V-Q-V-T-G-D-L-H-H-A-K-V-F-V-T-V-Y-G-T-K-D-E-A-Q-T-A-L-K-I-L-E-D-N-R-A-N-F-R-R-S-L-G-V-L-K-V-R-F-V-P-T-V-E-F-E-L-D-R-L-F-E-D-A-G-I-M-D-E-L-I-Q-R-A-R-E-S-D-K-R-I-A-A-G-A-S-G-P-I-D-N-D-A-T-A-L-M-D-K-V-V-D-Q-E-A-R-N-P-D-S-W-H-T-A-P-T-S-S-S-H-T-A-G-L-C-L-V-R-A-S-S-P-I-A-C-N-I-D-S-T-T-L-C-K-P-R-T-P-G-P-G-L


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-T-K-S-N-E-T-E-R-M-E-E-S-E-E-T-H-S-S-D-I-R-S-A-S-E-S-D-H-A-S-G-S-D-H-T-E-S-A-D-E-I-P-T-A-D-A-E-Q-G-E-L-E-Q-L-E-K-L-K-D-D-L-A-R-E-R-A-A-F-H-N-F-R-M-A-R-A-K-Q-A-E-I-E-R-D-R-T-R-S-E-V-I-R-V-I-L-P-V-L-D-D-F-A-R-I-E-K-H-S-T-L-D-D-P-F-K-A-V-I-T-K-L-R-S-A-M-E-K-I-G-L-T-A-F-G-N-P-G-D-P-F-N-P-E-L-H-E-A-L-F-Q-N-P-S-P-D-V-Q-T-E-T-V-Q-D-V-I-E-A-G-Y-C-L-G-E-T-V-I-R-A-A-K-V-V-V-Q-V-P-N-G


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Y-V-R-I-V-Q-D-L-I-R-E-L-G-K-L-P-G-I-G-P-K-S-A-Q-R-I-A-F-F-I-L-Q-N-P-S-F-D-I-D-R-L-S-E-T-L-Q-S-V-R-K-Q-V-Q-F-C-K-V-C-G-N-F-S-E-E-D-E-C-V-I-C-S-D-P-R-R-D-R-G-V-I-C-V-V-E-E-P-K-D-V-V-A-I-E-K-T-R-E-F-S-G-L-Y-H-V-L-G-G-A-I-S-P-I-D-G-V-G-P-D-D-L-N-I-R-Q-L-L-Q-R-L-A-D-G-T-I-T-E-V-V-L-A-T-D-P-N-M-E-G-E-A-T-A-S-Y-I-A-R-V-I-S-A-M-R-I-R-V-S-K-L-A-S-G-L-P-V-G-S-D-L-E-Y-A-D-E-I-T-L-G-R-A-L-E-G-R-Q-Y-I-N


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-N-V-F-S-G-W-H-L-L-V-I-L-L-V-I-V-L-L-F-G-T-S-R-L-P-K-L-S-K-S-V-V-E-A-L-K-I-F-R-R-S-F-N-E-A-S-D-I-T-R-S-Q-D-G-H-P-D-S-Q-G-N-F-A-E-S-A-S-S-V-P-F-V-K-S-E-K-Q-S-E-K-R-A-S-V-T-E-A-K-K-S-K


### FUNCTION The phosphoenolpyruvate-dependent sugar phosphotransferase system , a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane The enzyme II UlaABC PTS system is involved in ascorbate transport ### SEQUENCE -M-K-L-H-D-S-L-A-E-N-K-S-I-R-L-Q-A-E-A-E-T-W-Q-D-A-V-K-I-G-V-D-L-L-V-A-A-D-V-V-E-P-R-Y-Y-Q-A-I-L-D-A-V-E-Q-H-G-P-Y-F-V-L-A-P-G-L-A-M-P-H-G-R-P-E-E-G-V-K-K-T-G-F-A-L-V-T-L-K-K-P-L-E-F-N-H-E-D-N-D-P-V-D-I-L-I-T-M-A-A-V-D-A-N-T-H-Q-E-V-G-I-M-Q-I-V-N-L-F-E-D-E-E-N-F-D-R-L-R-A-C-R-T-E-Q-E-V-L-D-L-I-D-R-T-N-A-A-A


### FUNCTION Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion ### SEQUENCE -M-T-T-K-R-K-P-Y-V-R-P-M-T-S-T-W-W-K-K-L-P-F-Y-R-F-Y-M-L-R-E-G-T-A-V-P-A-V-W-F-S-I-E-L-I-F-A-L-F-A-L-K-N-G-P-E-A-W-A-G-F-V-D-F-L-Q-N-P-V-I-V-I-I-N-L-I-T-L-T-A-A-L-L-H-T-K-T-W-F-E-L-A-P-K-A-A-N-I-I-V-K-D-E-K-M-G-P-E-P-I-I-K-S-L-W-A-V-T-V-V-A-T-I-V-I-L-F-V-A-L-Y-W


### FUNCTION Involved in resistance toward heavy metals ### SEQUENCE -M-L-D-E-K-S-S-N-T-T-S-V-V-V-L-C-T-A-P-D-E-A-T-A-Q-D-L-A-A-K-V-L-A-E-K-L-A-A-C-A-T-L-I-P-G-A-T-S-L-Y-Y-W-E-G-K-L-E-Q-E-Y-E-V-Q-M-I-L-K-T-T-V-S-H-Q-Q-A-L-L-E-C-L-K-S-H-H-P-Y-Q-T-P-E-L-L-V-L-P-V-T-H-G-D-T-D-Y-L-S-W-L-N-A-S-L-R


### FUNCTION Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway ### SEQUENCE -M-M-R-Q-S-L-Q-A-V-L-P-E-I-S-G-N-K-T-S-L-L-R-K-S-V-C-S-D-L-L-T-L-F-N-S-P-H-S-A-L-P-S-L-L-V-S-G-M-P-E-W-Q-V-H-N-P-S-D-K-H-L-Q-S-W-Y-C-R-Q-L-R-S-A-L-L-F-H-E-P-R-I-A-A-L-Q-V-N-L-K-E-A-Y-C-H-T-L-A-I-S-L-E-I-M-L-Y-H-D-D-E-P-L-T-F-D-L-V-W-D-N-G-G-W-R-S-A-T-L-E-N-V-S


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-Q-A-Y-V-K-L-Q-V-A-A-G-M-A-N-P-S-P-P-V-G-P-A-L-G-Q-Q-G-V-N-I-M-E-F-C-K-A-F-N-A-K-T-D-S-I-E-K-G-L-P-I-P-V-V-I-T-V-Y-A-D-R-S-F-T-F-V-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-I-K-S-G-S-G-K-P-N-K-D-K-V-G-K-I-S-R-A-Q-L-Q-Q-I-A-Q-T-K-A-A-D-M-T-G-A-D-I-E-A-M-T-R-S-I-E-G-T-A-R-S-M-G-L-V-V-E-D


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-E-F-I-T-V-A-R-P-Y-A-K-A-A-F-D-F-A-V-E-H-Q-S-V-E-R-W-Q-D-M-L-T-F-A-A-E-V-T-K-N-E-Q-M-A-E-L-L-S-G-A-L-A-P-E-T-L-A-E-S-F-I-A-V-C-G-E-Q-L-D-E-N-G-Q-N-L-I-R-V-M-A-E-N-G-R-L-N-A-L-P-D-V-L-E-Q-F-I-H-L-R-A-V-S-E-A-T-A-E-V-D-V-I-S-A-A-A-L-S-E-Q-Q-L-A-K-I-S-A-A-M-E-K-R-L-S-R-K-V-K-L-N-C-K-I-D-K-S-V-M-A-G-V-I-I-R-S-G-D-M-V-I-D-G-S-V-R-G-R-L-E-R-L-A-D-V-L-Q-S


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-Q-D-A-V-E-K-I-G-N-R-F-D-L-V-L-V-A-A-R-R-A-R-Q-M-Q-V-G-G-K-D-P-L-V-P-E-E-N-D-K-T-T-V-I-A-L-R-E-I-E-E-G-L-I-N-N-Q-I-L-D-V-R-E-R-Q-E-Q-Q-E-L-E-A-A-E-L-Q-A-V-T-A-I-A-E-G-R-R


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-M-K-K-I-D-V-K-I-L-D-P-R-V-R-K-E-F-P-L-P-T-Y-A-T-S-G-S-A-G-L-D-L-R-A-C-L-D-D-A-V-E-L-A-P-G-D-T-T-L-V-P-T-G-L-A-I-H-I-A-D-P-S-L-A-A-M-M-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-I-D-S-D-Y-Q-G-Q-L-M-I-S-V-W-N-R-G-Q-D-S-F-T-I-Q-P-G-E-R-I-A-Q-M-I-F-V-P-V-V-Q-A-E-F-N-L-V-E-D-F-D-A-T-D-R-G-E-G-G-F-G-H-S-G-R-Q


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-T-I-A-K-H-R-H-A-R-S-S-A-Q-K-V-R-L-V-A-D-L-I-R-G-K-K-V-S-Q-A-L-D-I-L-T-Y-T-N-K-K-A-A-V-Q-V-K-K-V-L-E-S-A-I-A-N-A-E-H-N-D-G-A-D-I-D-D-L-K-V-T-K-I-F-V-D-E-G-P-S-M-K-R-I-M-P-R-A-K-G-R-A-D-R-I-L-K-R-T-S-H-I-T-V-V-V-S-D-R


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-M-H-K-G-R-N-R-G-L-A-Q-G-T-D-V-S-F-G-S-F-G-L-K-A-V-G-R-G-R-L-T-A-R-Q-I-E-A-A-R-R-A-M-T-R-A-V-K-R-Q-G-K-I-W-I-R-V-F-P-D-K-P-I-T-E-K-P-L-A-V-R-M-G-K-G-K-G-N-V-E-Y-W-V-A-L-I-Q-P-G-K-V-L-Y-E-M-G-G-V-P-E-E-L-A-R-E-A-F-K-L-A-A-A-K-L-P-I-K-T-T-F-V-T-K-T-V-M


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-A-K-I-R-R-D-D-E-V-I-V-L-T-G-K-D-K-G-K-R-G-K-V-K-N-V-L-S-S-G-K-V-I-I-E-G-I-N-L-V-K-K-H-Q-K-P-V-P-A-L-N-Q-P-G-G-I-V-E-K-E-A-A-I-Q-V-S-N-V-A-I-F-N-A-A-T-G-K-A-D-R-V-G-F-R-F-E-D-G-K-K-V-R-F-F-K-S-N-S-E-T-I-K


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-K-L-H-D-Y-Y-K-D-E-V-V-K-K-L-M-T-E-F-N-Y-N-S-V-M-Q-V-P-R-V-E-K-I-T-L-N-M-G-V-G-E-A-I-A-D-K-K-L-L-D-N-A-A-A-D-L-A-A-F-S-R-Q-K-P-L-S-T-K-A-R-K-F-V-A-C-F-K-I-R-Q-G-Y-P-I-G-C-K-V-T-L-R-G-E-R-M-W-E-F-F-E-R-L-I-T-I-A-V-P-R-I-R-D-F-R-G-L-S-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-R-E-Q-I-I-F-P-E-I-D-Y-D-K-V-D-R-V-R-G-L-D-I-T-I-T-T-T-A-K-S-D-E-E-G-R-A-L-L-A-A-F-D-F-P-F-R-K


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-S-V-L-Q-V-L-H-I-P-D-E-R-L-R-K-V-A-K-P-V-E-E-V-N-A-E-I-Q-R-I-V-D-D-M-F-E-T-M-Y-A-E-E-G-I-G-L-A-A-T-Q-V-D-I-H-Q-R-I-I-V-I-D-V-S-E-N-R-D-E-R-L-V-L-I-N-P-E-L-L-E-K-S-G-E-T-G-I-E-E-G-C-L-S-I-P-E-Q-R-A-L-V-P-R-A-E-K-V-K-I-R-A-L-D-R-D-G-K-P-F-E-L-E-A-E-G-L-L-A-I-C-I-Q-H-E-M-D-H-L-V-G-K-L-F-M-D-Y-L-S-P-L-K-Q-Q-R-I-R-Q-K-V-E-K-L-D-R-L-K-A-R-A


### FUNCTION Enhances recognition of ssrA-tagged proteins by the ClpX-ClpP protease ### SEQUENCE -M-D-L-S-Q-L-T-P-R-R-P-Y-L-L-R-A-F-Y-E-W-L-L-D-N-Q-L-T-P-L-L-V-V-D-V-T-L-P-G-V-Q-V-P-M-E-Y-A-R-D-G-Q-I-V-L-N-I-A-P-R-A-V-G-N-L-E-L-A-N-D-E-V-R-F-N-A-R-F-G-G-I-P-R-Q-V-S-V-P-L-A-A-V-L-A-I-Y-A-R-E-N-G-A-G-T-M-F-E-P-E-A-A-Y-D-E-D-T-S-I-M-N-D-E-E-A-S-A-D-N-E-T-V-M-S-V-I-D-G-D-K-P-D-H-D-D-D-T-H-P-D-D-E-P-P-Q-P-P-R-G-G-R-P-A-L-R-V-V-K


### FUNCTION In vitro catalyzes the addition of water to fumarate, forming malate Cannot catalyze the reverse reaction Cannot use the cis-isomer maleate as substrate ### SEQUENCE -M-A-T-L-T-E-D-D-V-L-E-Q-L-D-A-Q-D-N-L-F-S-F-M-K-T-A-H-S-I-L-L-Q-G-I-R-Q-F-L-P-S-L-F-V-D-N-D-E-E-I-V-E-Y-A-V-K-P-L-L-A-Q-S-G-P-L-D-D-I-D-V-A-L-R-L-I-Y-A-L-G-K-M-D-K-W-L-Y-A-D-I-T-H-F-S-Q-Y-W-H-Y-L-N-E-Q-D-E-T-P-G-F-A-D-D-I-T-W-D-F-I-S-N-V-N-S-I-T-R-N-A-T-L-Y-D-A-L-K-A-M-K-F-A-D-F-A-V-W-S-E-A-R-F-S-G-M-V-K-T-A-L-T-L-A-V-T-T-T-L-K-E-L-T-P


### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-D-Y-F-T-L-F-G-L-P-A-R-Y-Q-L-D-T-Q-A-L-S-L-R-F-Q-D-L-Q-R-Q-Y-H-P-D-K-F-A-S-G-S-L-A-E-Q-L-A-A-V-Q-Q-S-A-T-I-N-Q-A-W-Q-T-L-R-H-P-L-M-R-A-E-Y-L-L-S-L-H-G-F-D-L-A-S-E-Q-H-T-V-R-D-T-A-F-L-M-E-Q-L-E-L-R-E-E-L-D-E-I-E-Q-A-K-D-E-A-R-L-E-S-F-I-K-R-V-K-K-M-F-D-T-R-H-Q-L-M-V-E-Q-L-D-N-E-A-W-D-A-A-A-D-T-V-R-K-L-R-F-L-D-K-L-R-S-S-A-E-Q-L-E-E-K-L-L-D-F


### FUNCTION Catalyzes the dephosphorylation of heptose of the outer membrane lipopolysaccharide core ### SEQUENCE -M-L-A-F-C-R-S-S-L-K-S-K-K-Y-F-I-I-L-L-A-L-A-A-I-A-G-L-G-T-H-A-A-W-S-S-N-G-L-P-R-I-D-N-K-T-L-A-R-L-A-Q-Q-H-P-V-V-V-L-F-R-H-A-E-R-C-D-R-S-T-N-Q-C-L-S-D-K-T-G-I-T-V-K-G-T-Q-D-A-R-E-L-G-N-A-F-S-A-D-I-S-D-F-D-L-Y-S-S-N-T-V-R-T-I-Q-S-A-T-W-F-S-A-G-K-K-L-T-V-D-K-R-L-L-Q-C-G-N-E-I-Y-S-A-I-K-D-L-Q-S-K-A-P-D-K-N-I-V-I-F-T-H-N-H-C-L-T-Y-I-A-K-N-K-R-D-A-I-F-K-P-D-Y-L-D-G-L-V-M-H-V-E-K-G-K-V-Y-L-D-G-E-F-V-N-H


### FUNCTION Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD As a transcriptional regulator, acts as an anti-FlhDC factor ### SEQUENCE -M-N-N-A-P-H-L-Y-F-A-W-Q-Q-L-V-E-K-S-Q-L-M-L-R-L-A-T-E-E-Q-W-D-E-L-I-A-S-E-M-A-Y-V-N-A-V-Q-E-I-A-H-L-T-E-E-V-A-P-S-T-T-M-Q-E-Q-L-R-P-M-L-H-L-I-L-D-N-E-S-K-V-K-Q-L-L-Q-I-R-M-D-E-L-A-K-L-V-G-Q-S-S-V-Q-K-S-V-L-S-A-Y-G-D-Q-G-G-F-V-L-A-P-Q-D-N-L-F


### FUNCTION Catalyzes the excretion of spermidine ### SEQUENCE -M-A-Q-F-E-W-V-H-A-A-W-L-A-L-A-I-V-L-E-I-V-A-N-V-F-L-K-F-S-D-G-F-R-R-K-I-F-G-L-L-S-L-A-A-V-L-A-A-F-S-A-L-S-Q-A-V-K-G-I-D-L-S-V-V-Y-A-L-W-G-G-F-G-I-A-A-T-L-A-A-G-W-I-L-F-G-Q-R-L-N-R-K-G-W-I-G-L-V-L-L-L-A-G-M-I-M-V-K-L-A


### FUNCTION Required for growth and/or survival at acidic conditions ### SEQUENCE -M-K-K-V-L-A-L-V-V-A-A-A-M-G-L-S-S-A-A-F-A-A-E-T-A-T-T-P-A-P-T-A-T-T-T-K-A-A-P-A-K-T-T-H-H-K-K-Q-H-K-A-A-P-A-Q-K-A-Q-A-A-K-K-H-H-K-N-T-K-A-E-Q-K-A-P-E-Q-K-A-Q-A-A-K-K-H-A-G-K-H-G-H-Q-Q-P-A-K-P-A-A-Q-P-A-A


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-A-R-H-K-K-I-L-K-Q-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-R-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-A-R-Q-N-G-I-S-Y-S-K-F-I-N-G-L-K-K-A-S-V-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-V-A-F-T-T-L-V-E-K-A-K-A-A-L-A


### FUNCTION May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted ### SEQUENCE -M-N-E-A-V-S-P-G-A-L-S-T-L-F-T-D-A-R-T-H-N-G-W-R-E-T-P-V-S-D-E-T-L-Q-E-L-Y-A-L-M-K-W-G-P-T-S-A-N-C-S-P-A-R-I-V-F-I-R-T-A-E-G-K-E-R-L-R-P-A-L-S-S-G-N-L-Q-K-T-L-T-A-P-V-T-A-I-V-A-W-D-S-E-F-Y-E-R-L-P-L-L-F-P-H-G-D-A-R-S-W-F-T-S-S-P-Q-L-A-E-E-T-A-F-R-N-S-S-M-Q-A-A-Y-L-I-V-A-C-R-A-L-G-L-D-T-G-P-M-S-G-F-D-R-Q-H-V-D-D-A-F-F-A-G-S-T-L-K-S-N-L-L-I-N-I-G-Y-G-D-S-S-K-L-F-A-R-L-P-R-L-S-F-E-E-A-C-G-L-L


### FUNCTION Component of the SOS system and an inhibitor of cell division Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments In the presence of GTP, binds a polymerization-competent form of FtsZ in a 11 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division ### SEQUENCE -M-Y-T-S-G-Y-A-H-R-S-S-S-F-S-S-A-A-S-K-I-A-R-V-S-T-E-N-T-T-A-G-L-I-S-E-V-V-Y-R-E-D-Q-P-M-M-T-Q-L-L-L-L-P-L-L-Q-Q-L-G-Q-Q-S-R-W-Q-L-W-L-T-P-Q-Q-K-L-S-R-E-W-V-Q-A-S-G-L-P-L-T-K-V-M-Q-I-S-Q-L-S-P-C-H-T-V-E-S-M-V-R-A-L-R-T-G-N-Y-S-V-V-I-G-W-L-T-D-D-L-T-E-E-E-H-A-E-L-V-D-A-A-N-E-G-N-A-M-G-F-I-M-R-P-V-S-A-S-S-H-T-T-R-Q-L-S-G-L-K-I-H-S-N-L-Y-H


### FUNCTION Acts as a global negative controlling element, employing Fe ### SEQUENCE -M-T-D-N-N-T-A-L-K-K-A-G-L-R-V-T-L-P-R-L-K-I-L-E-V-L-Q-E-P-D-N-H-H-V-S-A-E-D-L-Y-K-R-L-I-D-M-G-E-E-I-G-L-A-T-V-Y-R-V-L-N-Q-F-D-D-A-G-I-V-T-R-H-N-F-E-G-G-K-S-V-F-E-L-T-Q-Q-H-H-H-D-H-L-I-C-L-D-C-G-K-V-I-E-F-S-D-D-S-I-E-A-R-Q-G-E-I-A-A-K-H-G-I-R-L-T-N-H-S-L-Y-L-Y-G-H-C-A-E-G-D-C-R-E-D-E-H-A-H-E-G-K


### FUNCTION Low-potential electron donor to a number of redox enzymes ### SEQUENCE -M-A-I-H-G-I-F-F-G-S-D-T-G-N-T-E-N-I-A-K-M-I-Q-K-Q-L-G-K-D-V-A-D-V-H-D-I-A-K-S-S-K-E-D-L-E-A-Y-D-I-L-L-L-G-I-P-T-W-Y-Y-G-E-A-Q-C-D-W-D-D-F-F-P-T-L-E-E-I-D-F-N-G-K-L-V-A-L-F-G-C-G-D-Q-E-D-Y-A-E-Y-F-C-D-A-L-G-T-I-R-D-I-I-E-P-R-G-A-T-I-D-A-D-W-P-T-A-G-Y-H-F-Q-A-S-K-G-L-A-D-D-D-H-F-V-G-L-A-I-D-E-D-R-H-P-E-L-T-A-D-R-V-E-K-W-V-K-Q-I-S-E-E-L-H-L-D-E-I-L-N-A


### FUNCTION Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP ### SEQUENCE -M-T-D-N-L-P-E-V-R-E-A-Q-E-W-F-R-S-E-T-R-R-V-A-P-I-T-L-D-V-M-W-D-H-F-L-S-R-H-W-S-Q-L-S-P-D-F-P-L-Q-E-F-V-C-Y-A-R-E-Q-V-M-T-I-L-P-D-S-P-P-R-F-I-N-L-N-N-Y-L-W-S-E-Q-W-L-V-R-Y-R-D-M-D-F-I-Q-N-V-L-N-G-M-A-S-R-R-P-R-L-D-A-L-R-D-S-W-Y-D-L-D-A-H-Y-D-A-L-E-T-R-F-W-Q-F-Y-P-R-M-M-A-Q-A-S-H-K-A-L


### FUNCTION Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 ### SEQUENCE -M-T-L-P-S-G-H-P-K-S-R-L-I-K-K-F-T-A-L-G-P-Y-I-R-E-G-K-C-E-D-N-R-F-F-F-D-C-L-A-V-C-V-N-V-K-P-A-P-E-V-R-E-F-W-G-W-W-M-E-L-E-A-Q-E-S-R-F-T-Y-S-Y-Q-F-G-L-F-D-K-A-G-D-W-K-S-V-P-V-K-D-T-E-V-V-E-R-L-E-H-T-L-R-E-F-H-E-K-L-R-E-L-L-T-T-L-N-L-K-L-E-P-A-N-D-F-R-D-E-P-V-K-L-T-A


### FUNCTION Overproduction of CaiE stimulates the activity of CaiB and CaiD ### SEQUENCE -M-S-Y-Y-A-F-E-G-L-I-P-V-V-H-P-T-A-F-V-H-P-S-A-V-L-I-G-D-V-I-V-G-A-G-V-Y-I-G-P-L-A-S-L-R-G-D-Y-G-R-L-I-V-Q-A-G-A-N-I-Q-D-G-C-I-M-H-G-Y-C-D-T-D-T-I-V-G-E-N-G-H-I-G-H-G-A-I-L-H-G-C-V-I-G-R-D-A-L-V-G-M-N-S-V-I-M-D-G-A-V-I-G-E-E-S-I-V-A-A-M-S-F-V-K-A-G-F-S-G-E-K-R-Q-L-L-M-G-T-P-A-R-A-V-R-S-V-S-D-D-E-L-H-W-K-R-L-N-T-K-E-Y-Q-D-L-V-G-R-C-H-A-S-L-H-E-T-Q-P-L-R-Q-M-E-E-N-R-P-R-L-Q-G-T-T-D-V-T-P-K-R


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-K-K-R-A-I-Q-S-E-K-A-R-K-I-I-A-S-R-R-S-M-M-R-P-F-I-K-K-G-D-A-A-I-E-A-G-D-K-A-A-A-Q-K-A-F-N-E-M-Q-P-I-V-D-R-Q-A-A-K-G-L-I-H-K-N-K-A-A-R-H-K-A-N-L-T-A-Q-I-N-K-L-A


### FUNCTION Specific electron transport protein capable of effectively supporting cytochrome P450 MycCI activity in the biosynthesis of mycinamicin, a 16-membered macrolide antibiotic ### SEQUENCE -M-R-I-V-L-D-A-E-R-C-V-G-A-G-Q-C-E-A-T-A-P-E-L-F-T-Q-G-D-D-G-L-G-L-V-R-D-R-P-V-T-P-E-L-L-G-P-A-R-E-A-V-D-R-C-P-V-R-A-I-R-I-E-S-S-V-R-T-G-W-A-R-G-A-G


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-I-R-P-L-H-D-R-V-I-V-E-R-K-E-V-E-S-K-S-A-G-G-I-V-L-T-G-S-A-A-E-K-S-T-R-G-V-V-L-A-V-G-K-G-R-I-L-E-N-G-T-V-L-P-L-D-V-K-V-G-D-T-V-I-F-A-E-G-Y-G-T-K-T-E-K-I-D-G-K-E-V-L-V-M-S-E-N-D-I-M-A-I-V-D-L-I-A-I-V-E


### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-T-I-T-D-P-S-K-L-A-Y-L-S-S-A-W-A-D-P-N-S-L-I-N-L-C-T-N-S-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-A-D-V-W-Q-P-V-P-T-L-T-S-R-F-P-A-G-A-G-H-F-R-V-Y-R-Y-E-P-I-L-E-P-L-I-T-F-L-M-G-T-F-D-T-R-N-R-I-I-E-V-R-N-P-Q-N-P-T-T-T-E-T-L-D-A-T-R-R-V-D-D-A-T-V-A-I-R-S-A-I-N-N-L-L-N-E-L-V-R-G-N-G-M-Y-N-Q-V-S-F-E-T-M-S-G-L-T-W-T-S-S


### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-T-I-T-D-P-S-K-L-A-Y-L-S-S-A-W-A-D-P-N-S-L-I-N-L-C-T-N-S-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-A-D-V-W-Q-P-V-P-T-L-T-S-R-F-P-A-G-A-G-Y-F-R-V-Y-R-Y-D-P-I-L-D-P-L-I-T-F-L-M-G-T-F-D-T-R-N-R-I-I-E-V-E-N-P-Q-N-P-T-T-T-E-T-L-D-A-T-R-R-V-D-D-A-T-V-A-I-R-S-A-I-N-N-L-L-N-E-L-V-R-G-T-G-M-Y-N-Q-V-S-F-E-T-M-S-G-L-T-W-T-S-S


### FUNCTION Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine  proteins that have critical roles in mRNA metabolism Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions ### SEQUENCE -M-A-D-D-S-A-L-H-K-K-Y-P-F-L-N-L-L-H-T-P-P-H-R-P-P-P-L-C-P-Q-A-P-R-K-T-Q-C-K-R-R-L-E-N-E-H-E-E-S-N-S-H-L-A-T-P-C-V-W-P-T-L-D-P-W-T-V-E-T-T-T-S-S-L-T-I-T-T-S-T-K-E-G-T-T-V-T-V-Q-L-R-L


### FUNCTION Plays a role in viral DNA replication ### SEQUENCE -M-A-Q-A-Q-I-D-E-Q-R-R-L-Q-D-L-Y-V-Q-L-K-K-E-I-N-D-G-E-G-V-A-W-L-F-Q-Q-K-T-Y-T-D-K-D-N-K-P-T-K-A-T-P-P-L-R-T-T-S-S-D-L-R-D-Y-W-T-K-L-E-C-H-N-C-H-E-E-Y-W-Q-L-T-T-Y-Y-C-K-E-C-R-K-C-E-H-G-K-L-R-H-T-K-K-E-C-E-Q-C-A-C-K-A-A-Q-E-T-S-A


### FUNCTION Plays a role in viral DNA replication ### SEQUENCE -M-A-Q-A-Q-I-D-E-Q-R-R-L-Q-D-L-Y-V-Q-L-K-K-E-I-N-D-G-E-G-V-A-W-L-F-Q-Q-K-T-Y-T-D-K-D-N-K-P-T-K-A-T-P-P-L-R-T-T-S-S-D-L-R-L-C-D-C-N-K-Q-H-Q-H-N-Q-S-N-C-W-M-C-G-N-K-R-S-R-R-A-T


### FUNCTION Potassium-selective channel essential in the virus replication cycle May be involved in preventing multiple infections ### SEQUENCE -M-L-V-F-S-K-F-L-T-R-T-E-P-F-M-I-H-L-F-I-L-A-M-F-V-M-I-Y-K-F-F-P-G-G-F-E-N-N-F-S-V-A-N-P-D-K-K-A-S-W-I-D-C-I-Y-F-G-V-T-T-H-S-T-V-G-F-G-D-I-L-P-K-T-T-G-A-K-L-C-T-I-A-H-I-V-T-V-F-F-I-V-L-T-L


### FUNCTION Involved in the dimethyl sulfide degradation pathway ### SEQUENCE -M-S-T-P-L-N-V-V-A-L-S-G-G-T-S-R-P-S-R-T-L-A-L-T-E-A-I-L-A-E-L-A-E-H-L-H-I-K-P-H-L-I-E-L-G-E-I-A-R-P-L-G-S-A-L-W-R-S-E-L-P-E-A-V-E-Q-Q-L-R-L-V-E-K-A-D-L-L-V-V-T-T-P-V-Y-R-G-S-F-T-G-H-F-K-H-L-F-D-L-I-G-Q-D-A-L-V-D-T-P-V-L-L-A-A-T-G-G-S-E-R-H-A-L-V-L-D-H-Q-L-R-P-L-F-S-F-L-Q-A-L-T-L-P-I-G-V-F-A-S-Q-A-E-M-A-D-Y-R-V-S-S-A-A-L-A-A-R-I-R-L-A-A-E-R-A-V-P-L-F-G-A-H-H-A-L-R-K-S-A


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-K-K-K-Y-T-I-R-K-K-I-F-G-F-L-E-K-P-R-V-S-I-F-R-S-N-K-H-I-Y-A-Q-V-I-D-D-Y-K-G-N-T-L-I-S-A-S-S-K-K-L-L-K-F-Y-K-K-R-R-E-K-K-I-T-K-K-E-L-S-Y-K-I-G-N-L-L-G-K-I-I-K-S-Y-G-I-S-K-I-L-F-D-R-N-G-Y-I-Y-H-G-R-V-K-A-L-A-K-G-L-R-N-V-G-L-Q-F


### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-P-Y-T-V-S-S-P-N-Q-L-V-Y-F-G-S-V-W-A-D-P-I-A-L-I-D-L-C-T-V-S-L-G-N-Q-F-Q-T-Q-N-A-R-T-T-V-Q-Q-Q-F-S-D-L-F-K-T-V-P-T-R-T-I-R-F-S-D-G-E-N-G-F-R-V-F-R-Y-N-S-T-L-D-P-L-I-T-A-L-L-N-S-F-D-T-R-N-R-I-I-E-T-E-N-P-A-N-P-N-T-A-E-I-A-S-A-T-Q-R-V-D-D-A-T-V-S-I-R-A-C-I-N-N-L-M-N-E-L-A-R-G-T-G-M-L-N-T-V-S-F-E-T-I-S-N-L-T-W-T-T-A-A-T-T


### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-A-Y-T-V-T-S-A-N-Q-L-V-Y-L-G-S-V-W-A-D-P-L-E-L-Q-N-L-C-T-S-A-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-S-D-V-W-K-T-I-P-T-A-T-V-R-F-P-A-T-G-F-K-V-F-R-Y-N-A-V-L-D-S-L-V-S-A-L-L-G-A-F-D-T-R-N-R-I-I-E-V-E-N-P-Q-N-P-T-T-A-E-T-L-D-A-T-R-R-V-D-D-A-T-V-A-I-R-A-S-I-S-N-L-M-N-E-L-V-R-G-T-G-N-Y-N-Q-A-L-F-E-S-V-S-G-L-T-W-A-T-T-P


### FUNCTION May act as a membrane anchor for the tetrachloroethene reductive dehalogenase PceA ### SEQUENCE -M-N-I-Y-D-V-L-I-W-M-A-L-G-M-I-A-L-L-I-Q-Y-G-I-W-R-Y-L-K-G-K-G-K-D-P-I-P-L-Q-I-C-G-F-L-A-N-F-F-F-I-F-A-L-A-W-G-Y-S-S-F-S-E-R-E-Y-Q-A-I-G-M-G-F-I-F-F-G-G-T-A-L-I-P-A-I-I-T-Y-R-L-A-N-H-P-A-K-K-I-R-E-S-S-D-S-I-S-A


### FUNCTION A DNA-binding protein that is part of the type III plasmid partition system used to ensure correct segregation of the pBM400 plasmid Binds the plasmid origin of replication, probably cooperatively, forming a ring or short helix with external DNA ### SEQUENCE -M-S-D-Y-F-E-E-V-M-R-K-L-T-I-E-D-V-S-I-L-G-W-L-F-Q-N-E-A-N-A-V-F-K-A-I-K-K-S-S-I-A-D-E-L-E-Y-S-T-A-N-F-R-K-T-L-N-K-L-E-A-I-H-F-I-G-T-V-T-G-G-K-E-H-K-L-Y-L-T-E-Y-G-Q-Q-A-V-Q-Q-A-I-H-H-G-E-E-N-E-E-V-E-E-I


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-Q-A-R-A-R-H-K-K-V-L-K-Q-A-K-G-Y-Y-G-A-R-S-R-V-Y-R-V-A-F-Q-A-V-T-K-A-G-Q-Y-A-Y-R-A-R-R-T-K-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-S-R-Q-N-G-L-S-Y-S-R-F-I-N-G-L-K-K-A-S-I-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-A-A-F-A-V-L-V-E-K-A-K-T-A-L


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-K-E-E-F-P-S-E-K-N-L-D-K-E-E-N-T-S-K-P-K-K-A-V-K-K-E-A-A-K-G-E-E-T-K-K-N-N-E-N-Q-K-L-A-K-E-I-A-D-L-K-E-K-N-K-D-L-E-D-K-Y-L-R-S-E-A-E-I-Q-N-M-Q-N-R-Y-T-K-E-R-A-Q-L-I-K-Y-E-S-Q-S-L-A-K-D-V-L-P-A-M-D-N-L-E-R-A-L-S-V-E-A-D-D-D-V-S-K-Q-L-K-K-G-V-Q-M-T-L-D-A-L-V-K-A-M-K-D-H-G-V-V-E-I-E-A-D-G-V-K-F-D-P-T-L-H-Q-A-V-Q-T-V-A-A-E-N-D-D-Q-K-D-H-V-V-Q-V-L-Q-K-G-Y-Q-Y-K-D-R-T-L-R-P-A-M-V-V-V-A-Q


### FUNCTION Inhibitor of the alkaline protease ### SEQUENCE -M-V-F-A-A-W-Y-L-K-F-A-F-F-V-A-L-A-F-S-I-I-G-G-S-M-A-S-S-L-V-L-P-H-A-S-E-L-K-G-V-W-Q-L-S-D-K-H-Q-Q-C-D-V-S-L-T-D-Q-P-L-P-E-G-S-I-W-S-L-N-G-D-N-D-C-L-A-Y-M-F-G-E-V-P-A-G-W-R-P-T-P-D-G-L-T-I-T-D-E-Q-G-S-G-L-A-F-F-A-N-E-P-D-G-W-F-A-R-F-A-D-G-R-E-L-M-M-K-P-N-K-T-N-K-K-N-E


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-S-K-I-V-K-L-Q-V-V-A-G-K-A-N-P-A-P-P-V-G-P-A-L-G-Q-A-G-V-N-I-M-G-F-C-K-E-F-N-E-R-T-K-D-K-A-G-L-I-I-P-V-E-I-T-V-F-E-D-R-S-F-T-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-K-I-E-K-A-S-G-E-P-N-K-N-K-V-A-K-L-P-R-A-E-A-M-K-I-A-E-S-K-M-E-D-L-N-A-A-D-I-E-A-A-T-R-M-I-E-G-T-A-R-S-M-G-I-E-I-V-D


### FUNCTION Heavy-metal-binding protein ### SEQUENCE -M-S-M-T-V-E-I-R-V-P-N-L-D-C-E-G-C-A-S-K-L-R-K-T-L-L-K-L-K-G-V-E-E-V-E-V-E-M-E-T-Q-K-V-T-A-R-G-Y-R-L-E-E-K-K-V-L-K-A-V-R-R-A-G-K-A-A-E-L-W-P-Y-R-L-G-N-S-H-F-A-S-F-Y-K-Y-P-S-Y-V-T-N-H-Y-Y-S-D-A-H-R-T-D-P-T-G-G-V-H-T-F-F-H-T-P-A-D-Y-S-V-A-V-A-G-D-E-I-A-A-S-M-F-S-D-D-N-P-H-A-C-T-I-M


### FUNCTION Potential calcium sensor ### SEQUENCE -M-E-G-L-T-S-E-Q-M-V-A-F-Q-E-A-F-L-L-F-D-K-N-G-D-G-C-I-T-L-E-E-L-A-A-V-T-R-S-L-G-L-E-P-T-D-Q-E-L-N-D-M-M-R-E-V-D-T-D-G-N-G-I-I-D-F-Q-E-F-L-S-L-I-A-R-K-M-K-D-G-D-G-D-E-E-L-K-E-A-F-E-V-L-D-K-D-Q-N-G-F-I-S-P-T-E-L-R-T-V-M-T-N-L-G-E-K-M-T-D-E-E-V-E-Q-M-I-R-E-A-D-T-D-G-D-G-Q-V-N-Y-D-E-F-V-I-M-M-K-N-A-E-R-K-I-S-G


### FUNCTION Variant histones H2A are synthesized throughout the cell cycle and are very different from classical S-phase regulated H2A May replace conventional H2A in a subset of nucleosomes Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling ### SEQUENCE -M-A-G-K-G-G-K-G-L-L-A-A-K-T-T-A-A-K-S-A-E-K-D-K-G-K-K-A-P-V-S-R-S-S-R-A-G-L-Q-F-P-V-G-R-I-H-R-Q-L-K-Q-R-T-Q-A-N-G-R-V-G-A-T-A-A-V-Y-S-A-A-I-L-E-Y-L-T-A-E-V-L-E-L-A-G-N-A-S-K-D-L-K-V-K-R-I-T-P-R-H-L-Q-L-A-I-R-G-D-E-E-L-D-T-L-I-K-G-T-I-A-G-G-G-V-I-P-H-I-H-K-S-L-I-N-K-S-S-K-E


### FUNCTION Probable transcription factor ### SEQUENCE -M-G-R-G-R-V-E-L-K-K-I-E-N-P-T-N-R-Q-V-T-F-S-K-R-R-M-G-L-L-K-K-A-N-E-L-A-I-L-C-D-A-Q-I-G-V-I-V-F-S-G-T-G-K-M-Y-E-Y-S-S-P-P-W-R-I-A-N-I-F-D-R-Y-L-K-A-P-S-T-R-F-E-E-M-D-V-Q-Q-R-I-I-Q-E-M-T-R-M-K-D-E-N-N-R-L-R-I-I-M-R-Q-Y-M-G-D-D-L-A-S-L-T-L-Q-D-V-S-N-L-E-Q-Q-I-E-F-S-L-Y-K-V-R-L-R-K-Q-Q-L-L-D-Q-Q-L-L-E-M-H-S-R-V-C-N-K-R-I-Y-R-F-S-I-L-P-Y-L-I-H-Y-I-E-I-I-K-F


### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-A-Q-R-E-K-K-V-E-E-P-T-E-L-R-A-P-E-M-T-L-C-A-N-S-C-G-F-P-G-N-P-A-T-N-N-L-C-Q-N-C-F-L-A-A-S-A-S-S-S-S-S-S-A-A-A-S-P-S-T-T-S-L-P-V-F-P-V-V-E-K-P-R-Q-A-V-Q-S-S-A-A-A-A-V-A-L-V-V-E-R-P-T-A-G-P-V-E-S-S-S-K-A-S-R-S-S-S-V-N-R-C-H-S-C-R-R-R-V-G-L-T-G-F-R-C-R-C-G-E-L-Y-C-G-A-H-R-Y-S-D-R-H-D-C-S-F-D-Y-K-S-A-A-R-D-A-I-A-R-E-N-P-V-V-R-A-A-K-I-V-R-F


### FUNCTION Probably acts as a transcriptional activator Binds to the GCC-box pathogenesis-related promoter element May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways ### SEQUENCE -M-E-G-S-S-S-S-M-Q-S-K-Y-K-G-V-R-K-R-K-W-G-K-W-V-S-E-I-R-L-P-N-S-R-E-R-I-W-L-G-S-Y-D-T-P-E-K-A-A-R-A-F-D-A-A-L-Y-C-L-R-G-N-N-A-K-F-N-F-P-D-N-P-P-V-I-S-G-G-R-N-L-S-R-S-E-I-R-E-A-A-A-R-F-A-N-S-A-E-D-D-S-S-G-G-A-G-Y-E-I-R-Q-E-S-A-S-T-S-M-D-V-D-S-E-F-L-S-M-L-P-T-V-G-S-G-N-F-A-S-E-F-G-L-F-P-G-F-D-D-F-S-D-E-Y-S-G-D-R-F-R-E-Q-L-S-P-T-Q-D-Y-Y-Q-L-G-E-E-T-Y-A-D-G-S-M-F-L-W-N-F


### FUNCTION Transcriptional repressor that may regulate multiple aspects of plant growth and development through the regulation of BEL1-LIKE  homeodomain transcription factors ### SEQUENCE -M-R-V-K-A-T-L-I-N-F-K-S-K-L-S-K-S-C-N-R-F-V-S-L-F-R-F-R-V-K-R-P-V-F-I-R-P-L-R-A-R-H-G-N-V-K-P-R-H-Q-H-H-H-S-K-K-P-I-C-S-C-L-C-F-L-N-S-S-K-N-H-K-M-S-N-A-K-H-R-S-S-S-F-S-V-N-D-D-D-Y-S-K-F-M-Q-S-P-L-T-P-A-T-A-K-K-L-F-T-S-P-I-T-T-P-Y-S-S-R-T-R-K-S-L-N-A-R-D-T-F-E-D-N-A-V-E-D-A-C-R-S-F-E-N-Y-L-I-H-L-I-V-E-E-G-K-I-D-D-L-M-D-I-E-E-L-L-F-C-W-K-N-L-K-S-P-V-F-I-E-L-V-S-R-F-Y-G-E-L-C-R-D-L-F-S-G-E


### FUNCTION Actin-depolymerizing protein Severs actin filaments ### SEQUENCE -M-A-N-A-T-S-G-V-A-V-S-E-E-C-K-A-R-F-Q-E-L-R-A-G-R-A-H-R-F-V-V-F-K-I-D-D-A-M-R-Q-V-V-V-D-R-V-G-P-R-D-A-G-F-D-E-L-T-A-S-L-P-A-D-G-C-R-Y-A-V-Y-D-H-D-F-T-V-S-D-A-T-A-T-A-A-A-G-E-G-G-E-A-P-R-S-K-I-F-F-V-S-W-S-P-A-A-A-D-V-R-S-K-M-V-Y-A-S-S-N-E-G-F-K-K-E-L-D-G-V-Q-I-D-L-Q-A-T-D-P-S-E-L-T-L-D-V-L-K-D-H-T-S


### FUNCTION Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism ### SEQUENCE -M-A-K-E-E-Y-V-S-R-M-L-V-M-L-I-M-I-M-P-L-V-A-Q-G-S-R-L-H-S-W-A-N-R-L-E-E-T-G-K-D-K-V-T-N-L-Q-F-Y-F-H-D-T-L-S-G-K-N-P-T-A-V-K-V-A-Q-G-T-D-T-E-K-S-P-T-L-F-G-A-V-F-M-V-D-D-A-L-T-E-T-A-D-P-K-S-K-L-V-G-R-A-Q-G-L-Y-G-S-S-C-K-E-E-V-G-L-I-M-A-M-S-F-C-F-E-D-G-P-Y-K-D-S-T-I-S-M-I-G-K-N-S-A-M-N-P-I-R-E-M-P-I-V-G-G-T-G-M-F-R-M-A-R-G-Y-A-I-A-R-T-N-W-F-D-P-K-T-G-D-A-I-V-G-Y-N-V-T-I-M-H


### FUNCTION Putative zinc finger that may be involved in programmed cell death and defense response ### SEQUENCE -M-Q-D-Q-L-I-C-S-G-C-R-R-V-V-Q-Y-R-R-G-V-A-G-V-C-C-P-G-C-N-T-L-T-A-V-N-P-S-A-V-A-D-M-S-E-L-I-C-S-G-C-P-T-L-L-F-Y-N-R-G-A-S-N-I-R-C-P-S-C-N-R-L-N-S-T-R-S-A-N-Q-I-A-H-L-T-C-G-Q-C-R-T-T-L-M-H-P-P-G-A-S-T-V-Q-C-A-T-C-R-Y-V-N-H-V-R-D-A-R-P-Q-T-V-L-V-E-N-P-K-T-L-D-D-K-G-K-L-V-S-N-V-V-V-G-V-T-S-W-K-R


### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations By binding to PIP2, it inhibits the formation of IP3 and DG ### SEQUENCE -M-S-W-Q-T-Y-V-D-D-H-L-M-C-D-I-E-G-N-H-L-S-S-A-A-I-L-G-H-D-G-T-V-W-A-Q-S-P-S-F-P-Q-L-K-P-E-E-V-S-A-I-M-K-D-F-N-E-P-G-S-L-A-P-T-G-L-H-L-G-G-T-K-Y-M-V-I-Q-G-E-P-G-D-V-I-R-G-K-K-G-P-G-G-V-T-I-K-K-T-N-Q-A-L-I-I-G-I-Y-G-E-P-M-T-P-G-Q-C-N-M-V-V-E-R-I-G-D-Y-L-V-E-Q-G-M


### FUNCTION Involved in regulation of actin and microtubule organization Part of a WAVE complex that activates the Arp2/3 complex ### SEQUENCE -M-A-R-A-G-G-H-G-M-G-N-P-V-N-V-G-I-A-V-Q-A-D-W-E-N-R-E-F-I-S-N-I-S-L-N-V-R-R-L-F-D-F-L-L-R-F-E-A-T-T-K-S-K-L-A-S-L-N-E-K-L-D-I-L-E-R-K-L-E-V-L-E-V-Q-V-S-S-A-T-T-N-P-S-V-F-N


### FUNCTION Potential calcium sensor ### SEQUENCE -M-G-G-K-E-L-S-E-E-Q-V-A-S-M-R-E-A-F-S-L-F-D-T-D-G-D-G-R-I-A-P-S-E-L-G-V-L-M-R-S-L-G-G-N-P-T-Q-A-Q-L-R-D-I-A-A-Q-E-K-L-T-A-P-F-D-F-P-R-F-L-D-L-M-R-A-H-L-R-P-E-P-F-D-R-P-L-R-D-A-F-R-V-L-D-K-D-A-S-G-T-V-S-V-A-D-L-R-H-V-L-T-S-I-G-E-K-L-E-P-H-E-F-D-E-W-I-R-E-V-D-V-A-P-D-G-T-I-R-Y-D-D-F-I-R-R-I-V-A-K


### FUNCTION May only reduce GSH-thiol disulfides, but not protein disulfides ### SEQUENCE -M-A-A-T-A-A-A-S-V-A-A-I-S-P-L-P-G-A-S-L-P-R-P-V-S-A-R-V-P-L-L-P-R-A-S-P-P-T-W-R-L-S-V-G-S-A-R-A-R-S-T-R-C-L-A-A-A-G-G-G-G-L-A-P-E-M-R-A-T-L-D-K-V-V-G-S-H-K-V-V-L-F-M-K-G-T-K-D-F-P-Q-C-G-F-S-H-T-V-V-Q-I-L-R-S-L-D-V-P-F-E-T-L-D-V-L-A-N-E-A-L-R-Q-G-L-K-E-Y-S-S-W-P-T-F-P-Q-L-Y-I-D-G-E-F-F-G-G-C-D-I-T-V-D-A-Y-K-S-G-E-L-Q-E-T-L-E-K-A-M-L-S


### FUNCTION Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates Responsible for the transcription of early, intermediate and late genes DNA-dependent RNA polymerase associates with the early transcription factor , itself composed of OPG118 and OPG133, thereby allowing the early genes transcription Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase ### SEQUENCE -M-M-N-Q-Y-N-V-T-Y-L-S-K-I-L-C-L-K-T-E-I-L-Y-K-P-F-S-I-I-N-R-S-I-V-N-Q-Y-N-I-D-V-K-Y-D-D-I-T-S-I-V-K-I-R-H-K-T-E-N-T-I-L-V-F-Q-I-F-N-E-S-N-V-K-Y-S-P-I-E-Y-D-Y-G-D-P-I-I-I-T-S-N-L-Q-H-G-H-N-R-I-P-I-N-M-L-Y-I-D-V-V-E-S-D-M-F-P-T-F-S-R-L-D-S-E-T-I-K-I-I-T-S-I-L-Q-S-D-N-K-K-E-Q-S-I-K-L-P-K-V-S-E-N-E-L-S-V-K-I-L-Y-H-K-D-Y-P-L-K-Y-V-R-Y-Y-K-N-N-M-V-T-G-I-E-V-I-D-R-S-V-A-I-T-S


### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-A-Q-E-S-W-K-K-E-A-E-E-T-G-V-H-T-P-E-A-P-I-L-C-V-N-N-C-G-F-F-G-S-R-M-T-E-N-M-C-S-K-C-Y-R-D-T-V-K-A-K-T-V-A-T-V-V-E-K-K-P-L-A-S-L-S-S-T-P-L-V-T-E-V-T-D-G-G-S-G-S-V-A-D-G-K-Q-V-M-E-E-D-T-P-K-P-P-S-N-R-C-L-S-C-R-K-K-V-G-L-T-G-F-K-C-R-C-G-G-T-F-C-S-M-H-R-Y-A-D-S-H-K-C-T-F-D-Y-K-Q-V-G-R-E-Q-I-A-K-Q-N-P-L-V-K-A-D-K-I-T-K-I


### FUNCTION May be involved in environmental stress response ### SEQUENCE -M-A-S-M-K-R-K-C-P-D-D-E-T-A-C-G-S-G-A-G-A-A-M-C-V-T-G-C-G-F-F-G-S-E-A-T-N-N-M-C-S-R-C-Y-R-E-H-S-A-D-N-D-A-V-E-E-A-A-A-A-N-S-D-L-E-L-V-G-V-A-E-T-T-T-K-K-A-R-M-S-A-V-V-P-V-A-V-A-S-S-S-S-A-A-A-E-Q-P-A-A-K-A-A-T-A-P-N-R-C-A-A-C-R-K-K-V-G-L-T-G-F-K-C-R-C-G-G-N-F-C-G-G-H-R-H-A-D-A-H-G-C-G-F-D-Y-K-S-A-G-K-E-Q-I-A-K-Q-N-P-L-V-V-A-D-K-L-A-T-R-I


### FUNCTION Constituent of viral factories Binds to ssRNA and dsRNA ### SEQUENCE -M-S-G-T-L-P-L-A-M-T-A-S-E-S-F-V-G-M-Q-V-L-A-Q-D-K-E-V-K-A-T-F-I-A-L-D-R-K-L-P-A-N-L-K-V-P-Y-M-K-N-A-K-Y-R-T-C-I-C-P-S-S-N-H-L-V-D-D-C-V-C-E-D-V-I-I-A-Y-T-A-H-R-N-N-A-V-A-A-L-L-Y-S-D-G-N-V-I-H-R-S-G-T-L-K-P-K-S-Q-N-R-F-D-L-R-G-F-L-T-S-V-N-P-G-E-S-S-K-A-E-A-G-T-S-K-S-T-Q-K-A-Y-D-R-K-D-K-S-P-S-K-G-K-N-S-K-K-G-G-K-K-S-S-S-E-R-K-R-K-E-Y-S-S-N-S-E-T-D-L-S-S-D-S-D-A-N-T-R-K-S-K-R-K


### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-Q-D-V-K-T-Y-L-S-T-A-P-V-L-A-T-L-W-F-G-F-L-A-G-L-L-I-E-I-N-R-S-F-S-D-A-L-V-L-P-F-F


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-A-Q-P-N-P-N-K-Q-S-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N


### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-I-V-N-I-A-W-A-A-L-M-V-V-S-T-S-S-L-S-P-V-A-W-G-R-S-G-L


### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-L-E-I-I-A-Q-L-T-V-L-A-L-I-I-A-S-G-P-L-V-I-A-L-L-A-A-R-K-G-N-L


### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-A-T-L-V-A-I-F-I-S-C-L-L-V-S-F-T-G-Y-A-P-Y-T-A-S-G-Q-P-S-N-E-L-R-D-L-F-E-E-H-E-D


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-G-T-L-G-I-I-F-F-A-I-F-F-R-D-P-P-K-V-P-S-K-G-V-P-S-K-G-K-K


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-I-A-T-A-L-F-I-L-I-P-T-A-F-L-L-I-L-Y-V-Q-T-A-S-Q-G-S


### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-N-W-E-S-E-W-F-R-I-E-L-I-R-G-S-R-R-I-S-N-F-F-W-A-F-I-L-L-S-G-A-L-G-F-L-S-V-G-L-S-S-Y-F-G-K-D-L-I-S-F-L-S-Y-E-Q-I-V-F-I-P-Q-G-I-V-M-C-F-Y-G-I-A-G-S-A-F-S-L-Y-L-W-G-T-I-F-W-N-I-G-S-G-Y-N-K-F-D-K-G-K-G-I-V-C-I-Y-R-W-G-F-P-G-K-N-R-R-I-R-I-E-F-S-M-K-D-I-E-A-I-G-M-E-V-Q-E-G-F-Y-P-R-R-T-L-R-L-K-I-K-G-Q-Q-D-V-P-L-T-Y-I-G-E-N-L-T-L-R-E-I-E-E-E-A-A-E-L-A-R-F-L-Q-I-S-I-E-G-F


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-L-L-K-K-G-P-F-V-A-Y-H-L-L-E-K-I-E-D-L-N-I-K-R-E-K-K-I-I-V-T-W-S-R-A-S-T-I-V-P-T-M-I-G-H-T-I-A-V-Y-N-G-Q-E-H-L-P-I-Y-I-T-D-R-M-V-G-H-K-L-G-E-F-A-L-T-R-V-F-K-G-H-A-K-S-D-K-K-S-R-R


### FUNCTION Essential for the assembly of the photosystem I  complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-Q-K-N-D-N-F-I-D-K-T-F-T-I-I-A-D-I-L-L-Q-I-I-P-T-T-Q-R-E-K-E-A-F-T-H-Y-R-D-G-M-S-A-Q-S-E-G-E-Y-A-E-A-L-Q-N-Y-Y-E-A-M-R-L-E-I-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-E-H-A-K-A-L-E-Y-Y-F-Q-A-L-E-R-N-S-S-L-P-Q-A-L-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-E-E-G-D-P-E-T-C-E-V-W-F-D-Q-A-A-D-Y-W-K-K-A-I-S-L-A-P-S-N-Y-I-E-A-Q-N-W-L-R-I-T-G-R-S-K-I-K


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-E-K-Q-N-L-I-D-M-E-G-V-V-T-E-S-L-P-N-A-M-F-R-V-C-L-D-N-G-C-Q-V-L-T-H-I-S-G-K-I-R-R-N-Y-I-R-I-L-P-G-D-R-V-K-V-E-L-S-P-Y-D-L-T-K-G-R-I-T-Y-R-L-R-T-K-S-S-N-P


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-N-T-T-G-R-I-P-L-W-L-I-G-T-I-A-G-I-L-V-I-G-L-V-G-I-F-F-Y-G-S-Y-S-G-L-G-S-S-L


### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-T-A-S-Y-L-P-S-I-L-V-P-L-V-G-L-V-F-P-A-I-T-L-A-S-L-F-I-Y-I-E-Q-D-E-I-V


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-L-F-V-Y-T-V-V-I-F-F-V-S-L-F-V-F-G-F-L-S-N-D-P-K-R-N-P-G-R-K-E


### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-N-Q-Q-L-I-R-K-A-R-Q-R-L-E-S-G-T-K-S-P-A-L-R-G-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-K-F-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-A-V-G-V-K-D-R-K-K-G-R-S-S-A-L-Q-S-I-V-A-T-R-I-I-A-T-I-P-Y-Q-L-F


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-S-K-R-G-P-F-V-A-N-H-L-I-R-E-I-R-N-L-N-I-Q-K-K-R-K-L-I-T-T-W-S-R-A-S-A-I-V-P-I-M-I-G-H-T-I-A-V-H-N-G-R-E-H-L-P-I-Y-V-T-D-R-M-V-G-H-K-L-G-E-F-V-P-T-R-N-F-R-G-H-A-K-S-D-K-G-S-R-R


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-K-Q-N-L-I-D-M-E-G-T-V-T-E-S-L-P-N-A-T-F-R-A-C-L-D-N-G-C-Q-V-L-T-H-I-S-G-R-M-R-R-S-Y-I-R-I-L-P-G-D-R-V-R-V-E-L-S-P-Y-D-L-T-K-G-R-I-I-Y-R-L-R-S-R-H-T-N-N-S-Q


### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-A-T-E-T-A-T-L-V-T-T-F-L-S-R-S-L-V-S-F-T-G-Y-A-L-Y-T-A-F-G-K-P-S-K-E-L-R-D-P-F-E-E-H-E-D


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-A-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-K-V-P-N-R-G-K


### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-Q-H-V-K-I-Y-L-S-T-A-P-V-V-A-T-I-W-F-G-L-L-A-G-L-L-I-E-I-N-R-F-F-P-D-A-L-L-F-P-F-P


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-P-N-P-N-K-Q-S-V-E-P-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-T-N-T-T-G-R-V-P-L-W-L-V-G-T-V-A-G-T-L-V-I-G-L-L-G-V-F-F-Y-G-A-Y-S-G-L-G-S-S-L


### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-N-S-R-P-T-W-I-Q-V-E-F-I-R-G-S-R-T-F-V-N-L-C-W-A-C-I-L-V-C-G-A-T-G-F-L-L-V-G-F-S-S-C-I-G-K-D-L-I-P-I-L-S-S-K-Q-I-A-F-I-P-Q-G-L-V-M-C-F-Y-G-I-A-G-L-F-L-G-L-Y-L-C-C-T-V-F-W-N-V-G-S-G-Y-N-Y-F-D-K-R-E-G-I-S-S-I-F-R-W-G-F-P-G-K-N-R-R-I-H-I-R-L-I-L-G-D-I-E-A-V-G-L-R-S-Q-E-G-L-F-P-S-R-I-L-Y-L-K-V-R-G-R-Q-S-I-P-L-T-R-I-G-E-N-S-T-P-E-Y-M-E-E-K-A-A-E-L-A-R-F-L-R-I-S-I-E-G-F


### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-T-A-S-Y-L-P-S-I-L-V-P-L-V-G-I-L-L-P-A-V-T-M-A-S-L-F-L-Y-I-E-R-D-E-I-L


### FUNCTION Essential for the assembly of the photosystem I  complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-Q-R-N-D-N-F-I-D-K-T-F-T-I-L-A-D-I-L-I-R-I-L-P-T-T-K-R-E-R-E-A-F-I-Y-Y-R-D-G-M-S-A-Q-S-E-G-E-Y-A-E-A-L-G-S-Y-Y-K-A-M-R-L-E-I-D-S-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-N-H-A-K-A-L-E-Y-Y-F-Q-A-L-E-R-N-S-F-L-P-Q-A-F-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-Y-Q-G-D-L-E-I-S-E-A-W-F-D-Q-A-A-E-Y-W-R-R-A-I-A-L-S-P-D-N-Y-A-E-A-Q-N-W-L-K-I-T-G-R-F-S-P-S-H-R-W-E-S-W-N-N-S-T-R-V-A


### FUNCTION Controls the interaction of photosystem II  cores with the light-harvesting antenna ### SEQUENCE -M-T-T-A-F-Q-F-A-L-F-A-L-I-A-T-S-F-L-L-V-V-G-V-P-V-A-F-A-S-P-G-G-W-S-D-N-K-N-I-V-F-S-G-A-S-L-W-I-G-L-V-F-L-V-G-I-P-N-S-F-I-S


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-F-V-A-T-A-L-F-I-L-I-P-T-A-F-L-L-I-L-Y-I-Q-T-A-A-Q-N-N-G


### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-L-E-I-I-T-Q-L-V-V-L-T-L-V-A-A-S-G-P-L-V-I-A-L-L-A-I-R-K-G-N-L


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-L-F-V-Y-A-V-V-I-F-F-V-S-L-F-V-F-G-F-L-S-N-D-P-G-R-N-P-G-R-K-D


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-T-V-S-Y-S-I-Y-L-E-N-S-L-H-F-G-D-A-L-L-A-K-L-P-E-A-Y-A-I-F-D-P-I-V-D-V-M-P-V-I-P-V-F-F-L-L-L-A-F-V-W-Q-A-A-V-S-F-R