### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-S-Q-E-I-R-A-I-V-R-I-G-D-T-D-L-D-G-N-K-Q-V-A-Y-A-L-A-K-I-R-G-I-G-I-A-S-A-Y-A-I-C-W-K-L-G-I-D-P-H-A-I-L-G-A-L-P-E-D-Q-I-N-K-L-D-W-A-V-R-N-L-H-E-L-A-P-A-W-F-L-N-R-R-K-D-P-E-T-G-R-D-L-H-L-I-G-S-E-L-V-L-A-A-K-R-D-V-D-L-M-K-K-L-K-S-W-K-G-V-R-H-S-L-G-L-K-V-R-G-Q-R-T-V-T-T-G-R-F-G-A-T-A-G-V-T-K-K-K-A-A-A-G-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-G-G-L-K-K-P-K-K-K-Y-L-A-G-K-P-K-K-I-W-N-K-Q-L-L-L-E-E-L-Q-L-M-G-E-Y-G-L-R-N-K-K-E-L-W-L-A-R-A-R-L-K-W-I-T-R-R-A-R-S-L-L-S-M-T-A-E-E-R-A-P-L-E-M-P-F-K-E-K-L-Y-K-M-G-F-I-E-D-P-N-V-Q-L-D-R-I-L-S-L-D-V-R-A-I-L-E-R-R-L-Q-T-I-V-Y-R-M-G-L-A-K-S-I-H-H-A-R-Q-L-I-V-H-G-H-V-A-V-A-G-R-R-V-T-S-P-G-F-L-V-P-R-E-L-E-D-K-I-S-L-I-Q


### FUNCTION Involved in ribosome biogenesis ### SEQUENCE -M-K-S-L-L-R-R-C-V-N-C-G-E-Y-T-L-S-K-D-K-C-P-R-C-G-G-A-V-R-V-P-H-P-P-K-F-S-P-E-D-K-Y-Q-K-Y-R-I-L-Q-K-L-L-M-G-K-L-P-I-R-D-E-T-K-E-R-L-L-R-D-L-T-S


### FUNCTION Broad-specificity nucleoside monophosphate  kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-F-D-A-R-R-P-K-A-L-I-T-G-T-P-G-V-G-K-T-T-H-C-R-K-L-A-A-F-L-N-T-K-C-I-S-V-G-E-L-L-A-G-T-P-Y-V-T-Y-I-P-E-L-D-T-Y-E-I-V-D-L-D-G-A-V-K-R-V-H-S-V-V-E-P-G-H-I-I-D-T-H-V-V-E-L-V-P-D-P-E-V-V-I-V-L-R-K-A-P-D-V-L-F-A-E-L-K-R-R-G-W-P-L-K-K-I-L-D-N-V-W-A-E-I-L-D-V-V-L-I-K-A-R-E-R-W-G-E-V-A-Q-I-D-V-T-R-R-R-P-E-E-T-F-E-L-L-K-K-C-V-A-G-G-R-C-H-S-D-V-V-D-W-L-G-Y-S-E-E-S-G-F-L-E-F-I-E-R-L-S-R-S-E-S-F


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-S-L-A-S-R-R-K-V-R-I-R-L-Y-G-T-N-P-A-D-V-E-Q-V-A-R-E-I-V-D-L-A-K-K-M-G-V-Q-V-R-G-P-I-P-L-P-T-R-R-L-I-V-T-V-R-R-A-P-S-G-Q-G-Y-H-T-F-D-H-W-E-M-R-I-S-K-R-L-I-D-I-E-A-S-E-R-V-L-R-R-L-M-T-I-R-V-P-D-T-V-K-I-E-L-Q-L-I


### FUNCTION Involved in protein export The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex ### SEQUENCE -M-A-R-R-R-K-Y-E-G-L-N-P-F-V-A-A-G-L-I-K-F-S-E-E-G-E-L-E-K-I-K-L-T-P-R-A-A-V-V-I-S-L-A-I-I-G-L-L-I-A-I-N-L-L-L-P-P-L


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-R-V-V-Y-S-V-E-E-V-E-I-P-K-G-V-S-V-S-I-E-R-T-G-P-F-D-Y-I-V-K-V-K-G-P-L-G-E-V-T-K-E-F-K-N-T-P-V-V-M-S-L-Q-D-G-K-I-V-M-E-V-F-K-A-R-K-R-E-Y-A-I-L-G-T-Y-K-G-I-L-K-N-M-F-L-G-V-T-R-G-W-R-Y-K-L-K-V-I-Y-T-H-F-P-M-L-V-K-V-Q-G-N-Q-L-V-I-E-N-F-L-G-R-K-S-K-I-T-L-N-I-P-K-G-V-K-V-E-V-K-G-K-E-D-I-V-I-E-G-I-D-R-E-L-V-S-T-F-A-A-A-V-Q-A-A-T-E-L-H-G-D-E-R-P-S-P-H-G-R-E-G-G-L-G-V-V-D-G-I-Y-V-V-G-Y-E-H-I-K-S


### FUNCTION Endonuclease that removes tRNA introns Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp ### SEQUENCE -M-I-G-Y-L-R-G-L-A-V-I-V-E-D-V-E-F-A-R-R-L-Y-K-E-G-F-Y-G-R-F-L-G-Y-D-K-V-K-R-D-E-V-E-K-I-N-A-P-L-I-L-G-L-Y-E-A-L-Y-L-A-E-K-G-R-L-K-V-M-G-E-D-G-R-E-V-A-P-E-E-L-A-A-L-G-R-E-R-M-R-N-F-D-E-I-Y-K-I-Y-K-Y-F-R-D-L-G-Y-V-V-K-S-G-L-K-F-G-A-L-F-S-V-Y-E-K-G-P-G-I-D-H-A-P-M-V-V-V-F-L-E-P-D-K-G-I-S-A-T-D-I-T-R-G-G-R-L-S-H-S-V-R-K-T-W-T-L-A-T-V-L-R-Q-T-G-E-V-V-L-L-G-F-G-W-A-R-L


### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-A-T-E-Q-T-I-L-V-G-K-K-P-T-T-N-Y-V-I-A-T-V-M-A-F-N-A-G-V-K-K-V-V-L-K-A-R-G-A-A-I-S-K-A-V-S-T-A-V-M-V-R-D-R-F-L-P-G-K-V-Q-I-K-D-I-K-L-L-S-D-K-V-Q-G-Q-G-G-R-E-R-T-V-A-A-I-E-V-V-L-E-M-A


### FUNCTION Molecular chaperone capable of stabilizing a range of proteins Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding ### SEQUENCE -M-A-Q-I-P-P-S-L-Q-D-L-V-N-R-F-N-Q-A-Q-A-Q-L-Q-N-V-L-L-R-K-Q-Q-Y-E-A-E-L-K-E-V-E-K-A-I-S-E-I-E-R-L-P-Q-D-A-K-I-F-K-N-V-G-N-F-L-V-P-Q-S-R-D-V-A-L-Q-E-L-R-D-R-K-E-L-L-E-L-H-V-K-T-L-T-R-Q-E-S-M-L-R-E-Q-L-D-K-L-R-E-E-I-N-K-E-L-A-K-L-K-G-G-A-T-E-A-A-K-G-G-G


### FUNCTION Specifically catalyzes the N1-methylation of pseudouridine at position 54  in tRNAs ### SEQUENCE -M-K-N-R-F-D-V-L-V-D-F-V-I-E-S-I-T-G-G-V-R-E-V-Y-V-M-L-C-D-G-S-T-Y-L-I-T-S-L-P-S-Q-R-A-R-A-V-A-R-W-L-L-S-R-Q-P-F-K-T-S-L-Q-A-I-I-A-K-Y-R-S-V-Y-Y-L-H-E-R-G-R-D-I-S-E-A-R-L-D-G-N-G-L-Y-I-F-G-D-H-D-G-L-S-R-E-D-E-E-L-L-A-K-H-A-E-W-I-S-L-G-S-T-P-Y-M-S-W-H-A-A-A-Y-L-A-Y-L-L-K-R-Q-V


### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-S-S-K-G-P-S-Y-R-I-E-N-I-V-A-T-V-N-L-G-V-E-L-D-L-E-Q-L-A-E-R-L-T-M-A-E-Y-N-P-D-Q-F-P-G-L-I-L-R-L-T-K-P-R-I-S-A-L-I-F-R-T-G-K-M-V-C-T-G-A-K-N-E-E-D-L-K-N-A-V-R-A-L-V-K-L-L-K-D-H-G-A-D-V-P-F-D-P-E-V-Q-I-Q-N-I-V-A-S-G-N-L-H-A-E-V-D-L-E-Q-A-V-L-M-L-E-N-A-M-Y-E-P-E-Q-F-P-G-L-I-Y-R-M-S-S-P-R-V-V-I-L-I-F-G-S-G-K-I-V-C-T-G-A-K-S-E-K-D-V-A-T-A-V-Q-K-L-Y-N-Q-L-K-E-L-G-V-L-Y-V-E-E-G-G-E-E-L-E-E-F-E-E-E-L


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-L-D-I-L-S-N-A-L-I-Q-I-K-N-A-E-I-V-G-K-K-Q-A-V-I-W-P-V-N-K-L-T-Y-Y-T-L-R-V-L-Q-R-Y-G-Y-V-G-E-I-E-Y-I-D-D-G-K-G-G-K-Y-I-V-Q-L-L-G-K-I-N-D-I-G-P-I-R-P-R-Y-P-V-K-Y-R-E-I-V-Q-W-E-Q-K-F-L-P-A-R-Q-I-G-I-L-I-I-S-T-S-Q-G-V-M-S-H-I-E-A-K-E-R-K-I-G-G-V-L-L-A-Y-V-Y


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-P-S-T-K-P-P-K-E-R-P-Y-G-K-S-K-I-R-C-L-R-C-G-T-R-E-A-V-I-R-K-Y-G-L-Y-L-C-R-R-C-F-R-E-V-A-P-Q-L-G-F-K-K-Y-Y


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-K-I-R-G-R-A-L-V-Y-G-D-K-I-D-T-D-V-I-I-P-A-K-Y-L-V-Y-T-D-P-A-L-L-G-Q-H-A-M-E-P-L-D-P-E-F-P-K-K-A-K-G-A-V-L-V-A-G-R-A-F-G-M-G-S-S-R-E-Q-A-A-L-A-L-K-G-A-G-V-L-A-V-V-A-E-S-F-A-R-I-F-F-R-N-A-I-N-V-G-L-P-V-L-Q-A-P-G-I-R-E-K-V-K-D-G-D-E-V-E-L-D-V-E-G-G-I-V-R-N-I-T-T-G-E-V-I-V-G-K-P-L-R-G-L-P-L-E-I-L-K-A-G-G-L-L-N-Y-L-K-N-S-R


### FUNCTION Probable zinc metalloprotease whose natural substrate is unknown ### SEQUENCE -M-R-P-R-I-T-V-V-A-P-S-R-I-K-P-L-E-I-P-E-F-T-T-I-W-Q-F-K-D-I-D-I-S-H-F-L-D-L-A-R-G-Q-C-R-A-D-K-V-V-E-A-L-S-N-G-V-K-S-P-T-V-Y-V-L-D-C-D-G-Y-Y-P-G-L-N-F-V-F-G-L-A-V-P-V-L-K-T-A-V-V-F-T-A-R-L-V-G-P-R-F-E-E-R-L-V-K-E-I-T-H-E-A-G-H-L-Y-G-L-A-H-C-A-N-P-S-C-V-M-Y-F-S-N-S-L-L-D-T-D-R-K-S-P-Y-F-C-P-K-C-R-E-N-L-A-R-I-L


### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-I-K-R-I-V-V-T-E-K-A-L-R-L-A-E-K-E-N-K-I-T-L-I-V-D-R-G-A-T-K-K-Q-I-A-E-E-V-E-R-L-Y-N-V-K-V-E-K-V-N-T-L-I-T-P-R-G-E-K-K-A-Y-V-K-L-T-K-E-H-N-A-M-D-L-L-S-K-L-G-V-L


### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-P-R-H-Q-S-Y-S-L-S-D-E-D-I-I-E-L-V-F-R-N-Y-G-V-K-I-T-P-E-Q-I-A-R-A-Y-A-P-E-Q-R-M-S-W-K-K-S-V-E-V-A-R-F-I-K-G-M-T-L-K-Q-A-K-T-W-L-E-D-V-V-K-L-K-R-P-V-P-I-K-T-F-K-K-K-Q-A-H-H-A-T-P-W-E-G-W-P-V-A-K-W-P-V-K-V-A-R-R-F-L-Q-V-L-E-N-L-E-N-N-A-R-F-R-G-L-D-V-D-R-V-V-I-V-H-A-A-A-H-K-G-F-K-I-P-N-I-M-P-R-A-F-G-R-A-T-R-F-D-E-Q-T-V-N-V-E-L-V-A-V-E-L-P-K-E-V-L-P-K-R-Y-K-L-N-L-V-K-R


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-V-K-N-I-G-I-P-H-V-L-P-P-A-S-V-C-D-D-P-L-C-P-W-H-G-H-L-K-V-R-L-K-L-L-E-V-T-V-E-K-V-R-M-H-K-A-A-V-V-I-H-E-W-L-H-Y-I-R-K-Y-N-R-Y-E-R-R-R-K-R-M-R-V-R-V-P-E-C-I-E-V-K-P-G-D-K-V-I-I-A-E-T-R-P-L-S-K-T-I-A-W-V-V-I-G-K-K-E-D-V-V-E-W-K-A-K-H-E-T-L-Q-A


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-S-S-K-E-Q-E-A-Q-K-G-K-Q-G-W-I-T-P-T-V-I-P-P-E-E-W-A-T-F-R-Y-R-G-K-T-L-E-E-L-L-N-M-S-M-D-E-F-I-K-L-L-P-A-R-Q-R-R-S-L-K-R-G-L-K-P-E-H-R-K-L-L-E-K-I-R-K-A-K-R-L-A-A-Q-G-K-K-V-V-I-R-T-H-C-R-D-M-I-I-L-P-E-M-V-G-L-T-I-H-V-Y-N-G-I-T-Y-I-P-V-F-I-S-P-W-H-I-G-H-Y-L-G-E-F-A-L-T-T-K-I-V-Q-H-G-E-P-G-L-K-A-T-R-S-S-L-H-I-A-A-K


### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently ### SEQUENCE -M-P-C-G-K-P-G-D-Y-K-Y-G-E-H-T-A-D-V-L-I-Q-A-Y-G-C-T-L-E-E-A-F-K-N-A-A-L-A-L-A-D-L-T-Y-Y-S-S-R-V-E-P-K-E-S-R-E-V-A-V-E-Y-E-D-L-E-G-L-L-F-R-W-I-D-E-L-L-Y-L-F-D-A-E-K-F-A-L-S-R-R-I-E-V-K-L-E-K-G-N-G-Y-A-I-R-A-L-L-Y-G-E-K-Y-D-I-N-K-H-G-F-T-G-L-I-V-K-A-M-T-Y-H-M-M-E-I-K-K-V-E-D-Y-W-L-V-Q-Y-V-V-D-I


### FUNCTION A probable chromatin protein, binds double-strand DNA without sequence specificity Constrains negative DNA supercoils ### SEQUENCE -M-A-E-E-I-L-N-R-E-Y-E-V-E-Y-E-G-R-K-Y-F-L-R-P-V-K-A-W-V-L-Q-P-P-G-K-P-G-V-V-V-A-L-F-K-L-P-N-G-K-S-I-R-K-V-I-M-R-L-P-P


### FUNCTION eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA ### SEQUENCE -M-D-S-E-Y-A-A-L-L-E-R-A-Y-K-L-V-A-P-K-A-Q-R-R-A-E-I-P-K-I-E-V-E-N-M-P-R-K-T-I-I-P-N-F-G-Q-I-A-K-R-L-N-R-D-V-Y-F-M-A-K-F-F-Q-K-E-L-A-V-P-G-T-L-E-G-D-V-F-T-L-H-G-E-K-S-P-K-V-V-E-A-V-Y-D-R-F-I-R-Y-Y-V-V-C-P-V-C-N-S-I-D-T-E-L-R-K-E-G-R-I-F-I-M-R-C-L-A-C-G-A-S-T-P-V-R-P-L


### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-A-R-L-R-I-I-N-F-Y-R-S-A-Y-C-S-A-M-S-E-F-R-L-P-G-E-G-E-I-L-G-K-V-I-E-M-L-G-D-G-R-F-K-V-I-C-A-D-G-Q-I-R-V-A-R-L-P-G-R-L-R-R-R-L-W-L-K-A-G-D-Y-V-I-V-A-L-W-D-F-D-R-E-K-G-D-I-V-H-K-Y-E-K-R-D-V-E-E-L-K-R-R-G-F-A-E-A-I-E-A-L-D-S-Y-A


### FUNCTION Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein  and RNA polymerase recruitment Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes ### SEQUENCE -M-K-D-V-Y-L-Y-I-V-E-K-S-V-A-W-E-F-D-S-P-E-Y-G-R-L-A-R-K-V-A-E-M-L-Y-E-R-K-E-D-L-T-D-D-R-I-A-I-L-L-N-I-S-T-A-E-T-R-R-I-L-Q-Y-L-M-R-L-N-L-V-G-V-K-K-R-T-T-E-D-Y-R-I-E-Y-T-W-Y-V-D-D-E-I-I-K-Q-A-I-G-G-R-A-R-T-A-R-E-K-I-S-M-L-I-R-A-L-T-E-G-S-Y-Y-I-C-P-N-C-H-M-R-Y-S-L-D-E-A-V-N-K-G-G-V-C-P-V-C-G-A-E-L-E-Y-V-E-S-L-E-E-I-N-K-L-T-K-V-L-Q-K-L-E-K-L


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-D-V-K-M-T-I-A-I-R-G-D-L-K-I-S-C-G-K-A-A-A-Q-A-G-H-A-A-V-E-C-V-L-A-A-M-G-D-A-K-W-R-K-W-L-D-Q-W-L-E-E-G-Q-K-K-I-V-L-T-A-D-D-A-A-H-L-Y-Q-L-H-E-R-A-K-S-L-G-L-P-T-A-V-V-I-D-A-G-L-T-E-L-P-P-G-T-P-T-A-I-C-V-G-P-A-P-D-E-L-V-D-K-V-T-G-S-L-K-L-Y-K


### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-S-A-E-V-A-L-V-Y-R-V-L-P-D-S-A-E-V-N-I-E-K-L-K-N-D-V-I-N-K-L-A-P-K-Y-K-V-D-K-V-E-V-E-E-I-G-F-G-I-K-A-L-R-L-Y-I-R-M-P-E-S-D-E-Y-S-S-D-E-I-E-E-L-L-R-S-V-E-G-V-G-G-Y-E-L-E-Y-F-S-R-L-S-F


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-N-V-V-K-R-P-L-D-I-S-Q-L-P-D-A-G-E-V-I-V-D-A-E-G-H-V-A-G-R-L-A-T-Y-I-A-K-A-L-L-E-R-P-N-L-R-I-V-V-V-N-A-E-K-L-V-I-T-G-D-E-K-M-V-I-E-W-F-K-R-K-I-S-E-W-R-T-H-Y-N-P-E-K-A-G-P-K-V-P-R-R-P-D-R-V-F-K-R-I-V-R-G-M-L-P-K-K-S-E-T-G-R-S-A-L-K-R-L-R-V-Y-M-S-I-P-I-E-I-M-Q-R-K-R-L-V-L-Y-E-V-P-E-A-K-L-R-L-R-P-L-L-Q-Y-T-T-L-E-E-V-W-R-S-I-D-P-E-A-W-E-K-W-R-R-A-V-E-V-W-G-K-K-L-K-Q-V-A-S-G


### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-G-K-K-S-P-Y-G-L-F-A-G-G-K-L-K-R-K-R-Q-K-F-R-W-N-D-V-T-Y-K-R-K-M-L-G-L-V-E-K-Y-D-P-L-E-G-A-P-M-A-R-G-I-V-L-E-K-V-G-V-E-A-R-K-P-N-A-A-V-R-K-C-V-R-V-Q-L-V-K-N-G-K-V-V-T-A-F-V-P-L-D-G-S-L-N-Y-I-N-E-H-D-E-V-V-I-E-R-I-G-G-P-E-G-R-S-L-G-D-I-P-G-V-R-F-K-V-I-K-V-N-G-V-S-L-W-A-I-W-R-G-K-K-Q-K-P-T-R


### FUNCTION DNA-dependent RNA polymerase  catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates ### SEQUENCE -M-S-R-I-S-L-G-V-K-E-V-T-V-I-P-R-E-E-A-K-E-L-L-K-R-M-K-L-R-P-W-Q-L-P-W-I-R-A-S-D-P-L-A-Q-K-A-G-A-K-P-G-D-V-L-K-I-V-R-E-S-P-T-A-G-E-A-V-V-Y-R-L-V-V-P-G


### FUNCTION Catalyzes the formation of CDP-2,3-bis- and CTP This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids ### SEQUENCE -M-D-L-T-V-F-F-L-L-I-W-P-P-Y-V-A-N-G-S-A-V-F-A-S-R-L-K-W-R-H-P-V-D-F-G-R-N-F-I-D-G-R-R-I-F-G-D-G-K-T-Y-E-G-V-A-I-G-I-A-T-G-T-V-L-G-Y-F-P-N-L-V-Y-H-V-I-G-V-F-D-A-F-V-L-S-A-S-A-V-L-G-D-L-I-G-A-F-I-K-R-R-L-C-M-P-R-G-H-P-A-F-P-L-D-Q-L-D-F-L-L-T-A-F-L-V-Y-S-L-F-R-E-I-P-V-V-Y-V-L-A-A-V-V-I-T-P-V-I-H-R-A-T-N-Y-V-A-Y-L-L-K-L-K-K-E-P-W


### FUNCTION Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7 ### SEQUENCE -M-S-W-P-Y-A-T-P-G-I-P-D-E-E-F-I-R-A-E-G-V-P-M-T-K-A-E-I-R-A-L-A-L-S-K-L-R-L-I-K-G-G-T-L-V-D-V-G-C-G-T-G-T-I-S-V-E-A-A-L-I-M-G-E-G-S-K-V-Y-A-I-D-K-D-P-L-A-V-E-I-T-K-K-N-A-A-K-F-G-V-G-D-R-L-I-V-A-E-G-D-A-L-E-L-L-P-K-L-P-R-S-N-R-Y-F-L-G-G-G-G-R-E-L-P-M-L-F-Q-T-A-L-E-L-A-G-T-G-G-V-I-V-A-D-V-I-T-L-E-S-L-R-L-A-L-D-F-L-E-N-A-G-V-K-Y-E-I-A-Q-V-Y-I-A-R-G-R-R-L-G-G-Y-T-I-L-S-P-L-N-P-V-Y-I-I-T-A-Y-A


### FUNCTION CRISPR  Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-Y-V-V-V-A-Y-D-I-T-E-D-E-V-R-N-K-V-A-D-A-L-K-A-Y-G-L-E-R-I-Q-R-S-V-F-V-G-R-I-N-P-A-L-L-K-D-L-V-E-R-L-K-R-I-T-K-G-A-N-A-D-I-T-I-F-K-V-D-R-R-A-I-D-T-A-I-R-I-G-P-P-P-P-A-R-K-N-V-D-L-Y


### FUNCTION Antitoxin component of a type II toxin-antitoxin  system ### SEQUENCE -M-S-E-V-I-S-I-R-V-R-R-G-L-K-K-E-L-E-E-L-G-I-N-Y-A-E-A-V-R-K-F-L-E-E-L-V-A-R-E-R-R-R-R-A-L-E-R-A-R-A-L-R-E-E-L-R-K-K-G-A-F-P-P-S-A-E-L-I-R-E-D-R-D-E-A-S-R


### FUNCTION CRISPR  Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-I-W-L-A-V-Y-D-I-E-D-D-G-E-R-A-K-A-S-A-I-L-Q-A-W-G-F-V-R-V-Q-R-S-F-Y-V-G-R-M-P-R-G-K-A-A-D-L-L-K-I-L-Q-R-H-V-K-S-G-H-I-A-L-I-P-I-T-D-E-L-L-A-K-A-L-E-L-G-R-P-P-Y-A-P-L-K-P-P-K-Y-A-Q-I-Y-V-V


### FUNCTION FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters ### SEQUENCE -M-A-F-N-G-T-W-Q-V-Y-S-Q-E-N-Y-E-D-F-L-K-A-I-A-L-P-D-D-I-I-K-A-A-K-D-V-K-P-V-T-E-I-R-Q-T-G-N-T-F-V-V-T-S-K-T-P-N-K-S-V-T-N-S-F-T-L-G-K-E-A-D-M-T-T-M-D-G-K-K-V-K-C-T-V-N-L-V-D-G-K-L-V-A-K-S-D-K-F-I-H-E-Q-E-I-V-G-N-E-M-V-E-T-I-T-S-G-S-A-T-F-T-R-R-S-K-K-I


### FUNCTION Contributes to the transparency and refractive index of the lens May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions ### SEQUENCE -R-A-L-G-P-L-I-P-S-R-L-F-D-Q-F-F-G-E-G-L-L-E-Y-D-L-L-P-L-F-S-S-T-I-S-P-Y-Y-R-Q-S-L-F-R-S-V-L-E-S-G-I-S-E-V-R-S-D-R-E-K-F-T-I-M-L-D-V-K-H-F-S-P-E-D-L-S-V-K-I-I-D-D-F-V-E-I-H-G-K-H-S-E-R-Q-D-D-H-G-Y-I-S-R-E-F-H-R-R-Y-R-L-P-S-N-V-D-Q-S-A-I-T-C-S-L-S-S-D-G-M-L-T-F-S-G-P-K-V-Q-A-N-M-D-P-S-H-S-E-R-P-I-P


### FUNCTION Has no ubiquitin ligase activity on its own The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63' This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome Plays a role in the activation of NF-kappa-B Mediates transcriptional activation of target genes Plays a role in the control of progress through the cell cycle and differentiation Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage ### SEQUENCE -M-A-A-T-T-G-V-K-V-P-R-N-F-R-L-L-E-E-L-E-E-G-Q-K-G-V-G-D-G-T-V-S-W-G-L-E-D-D-E-D-M-T-L-T-R-W-T-G-M-I-I-G-P-P-R-T-I-Y-E-N-R-I-Y-S-L-K-I-E-C-G-P-K-Y-P-E-A-P-P-F-V-R-F-V-T-K-I-N-M-N-G-V-N-S-S-N-G-V-V-D-P-R-A-I-S-V-L-A-K-W-Q-N-S-F-S-I-K-V-V-L-Q-E-L-R-R-L-M-M-S-K-E-N-M-K-L-P-Q-P-P-E-G-Q-C-Y-S-N


### FUNCTION Antimicrobial peptide ### SEQUENCE -M-K-F-T-A-T-F-L-V-L-S-L-V-V-L-M-A-E-P-G-E-C-F-L-G-A-L-I-K-G-A-I-H-G-G-R-F-I-H-G-M-I-Q-N-H-H-G-Y-D-E-Q-Q-E-L-N-K-R-A-V-D-E


### FUNCTION Serine protease inhibitor  Does not inhibit plasmin, and does not reduce blood loss in the mouse tail vein blood loss model ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-W-E-V-L-T-P-V-S-S-K-D-R-P-K-F-C-E-L-P-A-D-I-G-P-C-D-D-F-T-G-A-F-H-Y-S-P-R-E-H-E-C-I-E-F-I-Y-G-G-C-K-G-N-A-N-N-F-N-T-Q-E-E-C-E-S-T-C-A-A


### FUNCTION Serine protease inhibitor  Does not inhibit plasmin, and does not reduce blood loss in the mouse tail vein blood loss model ### SEQUENCE -M-S-S-G-G-L-L-L-L-L-G-L-L-T-L-W-E-V-L-T-P-V-S-S-K-D-R-P-K-F-C-E-L-L-P-D-T-G-S-C-E-D-F-T-G-A-F-H-Y-S-T-R-D-R-E-C-I-E-F-I-Y-G-G-C-G-G-N-A-N-N-F-I-T-K-E-E-C-E-S-T-C-A-A


### FUNCTION NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone ### SEQUENCE -M-H-P-N-L-V-S-W-L-G-T-L-G-L-L-L-W-A-L-L-C-L-S-A-L-T-E-G-Y-P-V-K-P-E-N-P-G-D-D-A-P-A-E-E-L-A-K-Y-Y-S-A-L-R-H-Y-I-N-L-I-T-R-Q-R-Y-G-K-R-S-S-P-E-I-L-D-T-L-V-S-E-L-L-L-K-E-S-T-D-T-L-P-Q-S-R-Y-D-P-S-L-W


### FUNCTION TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation TFIIA in a complex with TBP mediates transcriptional activity ### SEQUENCE -M-A-Y-Q-L-Y-R-N-T-T-L-G-N-S-L-Q-E-S-L-D-E-L-I-Q-T-Q-Q-I-T-P-Q-L-A-L-Q-V-L-L-Q-F-D-K-A-I-N-T-A-L-A-N-R-V-R-N-R-V-N-F-K-G-S-L-N-T-Y-R-F-C-D-N-V-W-T-F-V-L-N-D-V-E-F-R-E-V-T-D-L-V-K-V-D-K-V-K-I-V-A-C-D-G-K-N-T-G-N-A-A-E


### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-N-G-Q-G-A-S-A-D-P-Q-L-Q-Q-F-I-E-I-E-S-Q-K-Q-R-F-Q-Q-L-V-H-H-M-T-E-V-C-W-D-K-C-M-D-K-P-G-P-K-L-D-S-R-A-E-M-C-F-V-N-C-V-E-R-F-I-D-T-S-Q-F-I-L-N-R-L-E-Q-T-Q-R-S-K-G-S-F-S-E-T-M-T-D


### FUNCTION In muscle, parvalbumin is thought to be involved in relaxation after contraction It binds two calcium ions ### SEQUENCE -M-A-F-A-G-I-L-K-D-A-E-V-A-A-A-L-E-A-C-K-S-A-G-S-F-D-H-T-K-F-F-K-S-C-G-L-A-G-K-S-S-D-D-V-K-K-A-F-G-I-I-D-Q-D-Q-S-D-F-I-E-E-E-E-L-K-L-F-L-Q-N-F-S-A-S-A-R-A-L-S-D-A-E-T-K-A-F-L-K-A-G-D-S-D-G-D-G-K-I-G-V-D-E-F-A-A-M-V-K-A


### FUNCTION In muscle, parvalbumin is thought to be involved in relaxation after contraction It binds two calcium ions ### SEQUENCE -M-S-F-A-G-V-L-A-D-A-D-V-K-A-A-L-A-G-C-A-A-A-D-S-F-N-Y-K-T-F-F-K-A-C-G-L-A-A-K-S-H-E-E-V-K-K-A-F-F-V-I-D-Q-D-Q-S-G-F-I-E-E-D-E-L-K-L-F-L-Q-T-F-G-A-G-A-R-E-L-T-A-A-E-T-K-A-F-L-A-A-G-D-E-D-G-D-G-M-I-G-V-D-E-F-V-T-L-V-K-A


### FUNCTION In muscle, parvalbumin is thought to be involved in relaxation after contraction It binds two calcium ions ### SEQUENCE -M-A-F-A-G-I-L-N-D-A-D-I-T-A-A-L-A-A-C-K-A-E-G-S-F-D-H-K-A-F-F-T-K-V-G-L-A-A-K-S-P-A-D-I-K-K-V-F-E-I-I-D-Q-D-K-S-D-F-V-E-E-D-E-L-K-L-F-L-Q-N-F-S-A-G-A-R-A-L-S-D-A-E-T-K-V-F-L-K-A-G-D-S-D-G-D-G-K-I-G-V-D-E-F-G-A-M-I-K-A


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-G-H-Q-Q-L-Y-W-S-H-P-R-K-F-G-Q-G-S-R-S-C-R-V-C-S-N-R-H-G-L-I-R-K-Y-G-L-N-M-C-R-Q-C-F-R-Q-Y-A-K-D-I-G-F-V-K-L-D


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-D-A-S-R-V-Q-P-I-K-L-A-R-V-T-K-V-L-G-R-T-G-S-Q-G-Q-C-T-Q-V-R-V-E-F-M-D-D-S-N-R-S-I-I-R-N-V-K-G-P-V-R-E-G-D-V-L-T-L-L-E-S-E-R-E-A-R-R-L-R


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-P-P-K-D-S-K-Q-K-K-D-T-S-K-A-K-K-D-K-D-P-V-N-K-S-G-G-K-A-K-K-K-K-W-S-K-G-K-V-R-D-K-L-N-N-L-V-L-F-D-K-A-T-Y-D-K-L-Y-K-E-V-P-N-Y-K-L-I-T-P-A-V-V-S-E-R-L-K-I-R-G-S-L-A-R-A-A-L-L-E-L-L-S-K-G-M-I-K-L-V-S-K-H-R-A-Q-V-I-Y-T-R-N-T-K-G-T-D-E-G-A-P-E-K-E-A


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-Q-N-D-A-G-E-F-V-D-L-Y-V-P-R-K-C-S-A-S-N-R-I-I-G-A-K-D-H-A-S-I-Q-I-N-I-A-E-V-D-K-V-T-G-R-F-N-G-Q-F-K-T-Y-A-I-C-G-A-I-R-R-M-G-E-A-D-D-S-L-L-R-L-A-K-N-D-S-I-V-S-K-N-I


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-S-L-V-I-P-E-K-F-Q-H-I-L-R-V-L-N-T-N-I-D-G-R-R-K-I-A-F-A-I-T-A-I-K-G-V-G-R-R-Y-A-H-V-V-L-R-K-A-D-I-D-L-S-K-R-A-G-E-L-T-E-D-E-V-E-R-V-V-T-I-M-Q-N-P-R-Q-Y-K-I-P-D-W-F-L-N-R-Q-K-D-V-K-D-G-K-Y-S-Q-V-L-A-N-G-L-D-N-K-L-R-E-D-L-E-R-L-K-K-I-R-A-H-R-G-L-R-H-F-W-G-L-R-V-R-G-Q-H-T-K-T-T-G-R-R-G-R-T-V-G-V-S-K-K-K


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-G-R-V-R-T-K-T-V-K-K-A-A-R-V-I-I-E-K-Y-Y-T-R-L-G-N-D-F-H-T-N-K-R-V-C-E-E-I-A-I-I-P-S-K-K-L-R-N-K-I-A-G-Y-V-T-H-L-M-K-R-I-Q-R-G-P-V-R-G-I-S-I-K-L-Q-E-E-E-R-E-R-R-D-N-Y-V-P-E-V-S-A-L-D-Q-E-I-I-E-V-D-P-D-T-K-E-M-L-K-L-L-D-F-G-S-L-S-N-L-Q-V-T-Q-P-T-V-G-M-N-F-K-T-P-R-G-V


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-P-A-K-G-P-L-Q-S-V-Q-V-F-G-R-K-K-T-A-T-A-V-A-H-C-K-R-G-N-G-L-I-K-V-N-G-R-P-L-E-T-I-E-P-A-T-L-Q-Y-K-L-L-E-P-V-L-L-L-G-K-E-R-F-A-G-V-D-I-R-V-R-V-K-G-G-G-H-V-A-Q-V-Y-A-I-R-Q-S-I-S-K-A-L-V-A-Y-Y-Q-K-Y-V-D-E-A-S-K-K-E-I-K-D-I-L-I-Q-Y-D-R-T-L-L-V-A-D-P-R-R-C-E-S-K-K-F-G-G-P-G-A-R-A-R-Y-Q-K-S-Y-R


### FUNCTION Component of the 40S ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-L-M-P-K-K-N-R-I-A-I-Y-E-L-L-F-K-E-G-V-M-V-A-K-K-D-V-H-L-A-K-H-P-E-L-A-D-K-N-V-P-N-L-H-V-M-K-A-M-Q-S-L-K-S-C-G-Y-V-K-E-Q-F-A-W-R-H-F-Y-W-Y-L-T-N-E-G-I-Q-Y-L-R-D-F-L-H-L-P-P-E-I-V-P-A-T-L-R-R-Q-T-R-P-E-T-A-R-P-R-P-K-G-L-E-G-E-R-P-A-R-L-A-R-G-E-G-D-R-D-A-Y-R-R-S-A-A-P-P-G-A-D-K-K-A-E-A-G-A-G-A-A-T-E-F-Q-F-R-G-G-F-G-R-G-R-G-Q-Q-P-Q


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-R-A-K-W-R-K-K-R-M-R-G-L-K-R-K-R-R-K-M-R-Q-R-S-K


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-K-R-T-K-K-V-G-I-V-G-K-Y-G-T-R-Y-G-A-S-L-R-K-M-V-K-K-I-E-I-S-Q-H-A-K-Y-T-C-S-F-C-G-K-T-K-M-K-R-R-A-V-G-I-W-H-C-G-S-C-M-K-T-V-A-G-G-A-W-T-Y-N-T-T-S-A-V-T-V-K-S-A-I-K-R-L-K-E-M-K-D-Q


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-T-K-G-T-S-S-F-G-K-R-R-N-K-T-H-T-L-C-R-R-C-G-S-K-A-Y-H-L-Q-K-S-T-C-G-K-C-G-Y-P-A-K-R-K-R-K-Y-N-W-S-A-K-A-K-R-R-S-T-T-G-T-G-R-M-R-H-M-K-V-V-F-R-R-F-R-N-G-F-R-E-G-T-V-P-K-P-R-R-A-A-V-A-A-S-S-S-S


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-I-R-Y-P-M-A-V-G-L-K-K-G-H-P-V-T-K-N-V-T-K-P-K-H-S-R-R-G-G-R-L-T-K-H-S-K-F-V-R-D-M-I-R-E-V-C-G-F-A-P-Y-E-R-R-A-M-E-L-L-K-V-S-K-D-K-R-A-L-K-F-I-K-K-R-V-G-T-H-I-R-A-K-R-K-R-E-E-L-S-N-I-L-A-A-M-R-K-A-A-A-K-K-E


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-P-G-R-L-W-C-K-A-I-F-A-G-Y-K-R-G-L-R-N-Q-R-E-H-T-A-L-L-K-V-E-G-V-Y-S-R-N-E-V-D-F-Y-L-G-K-R-C-A-Y-V-Y-K-A-K-K-T-T-V-T-P-G-G-K-P-N-K-T-R-V-I-W-G-K-V-T-R-A-H-G-N-S-G-M-V-R-A-K-F-T-S-N-L-P-P-K-A-I-G-H-R-I-R-V-M-L-Y-P-S-R-V


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-K-I-K-A-R-D-L-R-G-K-K-K-E-E-L-L-K-H-V-D-D-L-K-V-E-L-S-Q-L-R-V-A-K-V-T-G-G-A-A-S-K-L-S-K-I-R-V-V-R-K-S-I-A-R-V-L-T-V-I-N-Q-T-Q-K-E-N-L-R-K-F-Y-K-G-K-K-Y-K-P-L-D-L-R-P-R-K-T-R-A-I-R-R-Q-L-T-K-H-E-Q-G-L-M-T-K-K-M-Q-R-R-S-R-L-Y-S-M-R-K-F-A-V-K-A


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-V-Q-R-L-T-Y-R-R-T-V-S-Y-N-T-T-S-N-K-T-R-L-S-R-T-P-G-N-R-I-V-Y-L-Y-T-K-K-T-G-K-A-P-K-S-A-C-G-I-C-P-G-R-L-R-G-I-R-A-V-R-P-Q-V-L-M-R-L-S-K-T-K-K-H-V-S-R-A-Y-G-G-S-M-C-A-K-C-V-R-D-R-I-K-R-A-F-L-I-E-E-Q-K-I-V-V-K-V-L-K-A-Q-A-Q-S-Q-K-A-K


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-A-L-R-P-L-T-K-P-K-I-V-K-K-R-T-K-K-F-I-R-H-Q-S-D-R-Y-V-K-I-R-R-N-W-R-K-P-R-G-I-D-N-R-V-R-S-G-F-K-G-Q-M-L-M-P-N-I-G-Y-G-S-N-K-K-T-K-H-M-L-P-S-G-F-K-K-F-L-V-H-N-V-K-E-L-E-V-L-L-M-S-N-K-S-Y-C-A-E-I-A-H-N-V-S-S-K-N-R-K-V-I-V-E-R-A-A-Q-L-A-I-K-V-T-N-P-N-A-R-L-R-S-E-E-N-E


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-P-L-K-K-G-G-E-K-K-K-G-R-S-A-I-N-E-V-V-T-R-E-Y-T-I-N-V-H-K-R-I-H-G-I-S-F-K-K-R-A-P-R-A-I-K-E-I-R-K-F-A-M-K-E-M-G-T-P-D-V-R-I-D-T-R-L-N-K-A-V-W-A-K-G-V-R-N-V-P-Y-R-M-R-V-R-L-S-R-K-R-N-E-D-E-D-S-P-N-K-L-Y-T-L-V-T-Y-V-P-V-T-T-Y-K-G-L-Q-T-V-N-V-D-E-N


### FUNCTION Component of the large ribosomal subunit ### SEQUENCE -M-G-K-F-M-K-P-G-K-V-V-M-V-L-A-G-R-Y-A-G-R-K-A-V-I-V-K-N-I-D-D-G-T-A-D-R-P-Y-S-H-A-L-V-S-G-I-D-R-Y-P-R-K-V-T-A-T-M-G-K-K-K-V-A-K-R-S-K-I-K-A-F-V-K-V-F-N-Y-N-H-L-M-P-T-R-Y-S-V-D-I-P-L-D-K-T-I-V-N-K-D-V-F-R-D-P-A-L-K-R-K-A-R-R-E-A-K-V-K-F-E-E-R-Y-K-T-G-K-N-K-W-F-F-Q-K-L-R-F


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-K-V-E-L-C-S-F-S-G-Y-K-I-Y-P-G-H-G-P-V-Y-A-R-I-D-G-K-V-F-Q-F-L-N-A-K-C-E-S-A-F-L-T-K-R-N-P-R-Q-I-N-W-T-V-L-Y-R-R-K-H-K-K-G-Q-S-E-E-V-T-K-K-R-T-R-R-A-V-K-F-Q-R-A-I-T-G-A-S-L-A-E-I-L-A-K-R-N-Q-K-P-E-V-R-K-A-Q-R-E-Q-A-I-R-A-A-K-E-A-K-K-A-K-Q-A-T-K-K-V-S-T-Q-S-T-K-A-P-A-K-A-A-P-K-Q-K-I-A-K-P-M-K-V-S-A-P-R-V-G-G-K-R


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-S-K-R-G-R-G-G-S-S-G-A-K-F-R-I-S-L-G-L-P-V-G-A-V-I-N-C-A-D-N-T-G-A-K-N-L-Y-I-I-S-V-K-G-I-K-G-R-L-N-R-L-P-A-A-G-V-G-D-M-V-M-A-T-V-K-K-G-K-P-E-L-R-K-K-V-H-P-A-V-V-I-R-Q-R-K-S-Y-R-R-K-D-G-V-F-L-Y-F-E-D-N-A-G-V-I-V-N-N-K-G-E-M-K-G-S-A-I-T-G-P-V-A-K-E-C-A-D-L-W-P-R-I-A-S-N-A-G-S-I-A


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-A-P-L-K-K-P-A-V-K-G-G-K-K-K-K-Q-V-L-K-F-T-L-D-C-T-H-P-V-E-D-G-I-M-D-A-A-N-F-E-Q-F-L-Q-E-R-I-K-V-N-G-K-A-G-N-L-G-G-G-V-V-S-I-E-R-S-K-S-K-I-T-V-T-S-D-I-P-F-S-K-R-Y-L-K-Y-L-T-K-K-Y-L-K-K-N-N-L-R-D-W-L-R-V-V-A-N-T-K-E-S-Y-E-L-R-Y-F-Q-I-N-Q-D-E-E-E-E-E-D-E-D


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-S-M-L-R-L-Q-K-R-L-A-S-S-V-L-R-C-G-K-K-K-V-W-L-D-P-N-E-T-N-E-I-A-N-A-N-S-R-Q-A-I-R-K-L-V-K-D-G-L-I-I-K-K-P-V-T-V-H-S-R-A-R-C-R-K-N-T-L-A-R-R-K-G-R-H-M-G-I-G-K-R-K-G-T-A-N-A-R-M-P-E-K-L-C-W-M-R-R-M-R-I-L-R-R-L-L-R-R-Y-R-E-S-K-K-I-D-R-H-M-Y-H-S-L-Y-L-R-A-K-G-N-V-F-K-N-K-R-I-L-M-E-H-I-H-K-L-K-A-D-R-A-R-K-K-L-L-S-D-Q-A-E-A-R-R-S-K-T-R-E-A-R-K-R-R-E-E-R-L-Q-A-K-K-E-E-I-I-K-N-L-S-K-E-E-E-G-K-K


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-K-A-S-G-T-L-R-E-Y-K-V-V-G-R-L-L-P-S-A-K-N-P-T-P-P-L-Y-R-M-R-I-F-A-P-N-H-V-V-A-K-S-R-F-W-Y-F-V-S-Q-L-R-K-M-K-K-A-N-G-E-T-V-Y-C-G-L-V-H-E-Q-S-P-L-K-V-K-N-F-G-I-W-L-R-Y-D-S-R-S-G-T-H-N-M-Y-R-E-Y-R-D-L-T-T-S-G-A-V-T-Q-C-Y-R-D-M-G-A-R-H-R-A-R-A-H-A-I-Q-I-M-K-V-Q-V-I-A-A-N-K-C-R-R-A-A-I-K-Q-F-H-D-S-K-I-K-F-P-L-P-H-R-V-L-R-R-Q-H-K-P-R-F-T-T-R-R-P-Q-T-F-F


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-G-V-D-I-R-H-N-K-D-R-K-V-H-R-T-E-P-K-S-Q-D-I-Y-L-R-L-L-V-K-L-Y-R-F-L-A-R-R-S-D-A-P-F-N-K-V-V-L-K-R-L-F-M-S-K-T-N-R-P-P-L-A-L-S-R-L-I-R-K-M-K-L-Q-G-R-E-N-K-I-A-V-V-V-G-T-I-T-D-D-V-R-I-L-N-I-P-K-L-K-V-C-A-L-R-V-T-A-G-A-R-R-R-I-L-K-A-G-G-Q-V-M-T-F-D-Q-L-A-V-T-T-P-K-G-Q-G-T-V-L-L-S-G-P-R-K-A-R-E-V-Y-R-H-F-G-K-A-P-G-T-P-H-S-H-T-K-P-Y-I-R-S-K-G-R-K-F-E-R-A-R-G-R-R-A-S-R-G-Y-K-N


### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-A-D-Q-G-E-K-K-E-N-P-M-R-E-L-R-I-R-K-L-C-L-N-I-C-V-G-E-S-G-D-R-L-T-R-A-A-K-V-L-E-Q-L-T-G-Q-T-P-V-F-S-K-A-R-Y-T-V-R-S-F-G-I-R-R-N-E-K-I-A-V-H-C-T-V-R-G-A-K-A-E-E-I-L-E-K-G-L-K-V-R-E-Y-E-L-R-K-N-N-F-S-D-S-G-N-F-G-F-G-I-Q-E-H-I-D-L-G-I-K-Y-D-P-S-I-G-I-Y-G-L-D-F-Y-V-V-L-G-R-P-G-F-S-I-A-D-K-K-R-K-R-G-R-I-G-F-K-H-R-I-R-K-R-E-A-M-R-W-F-Q-Q-K-Y-D-G-V-I-L-P-G-K


### FUNCTION Component of the large ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ### SEQUENCE -M-K-T-I-L-S-T-Q-T-V-D-I-P-D-N-V-D-V-T-L-K-G-R-T-V-S-V-K-G-P-R-G-V-L-R-R-E-F-N-H-I-N-L-E-L-R-L-L-G-K-K-Q-K-K-L-R-V-D-K-W-W-G-N-R-K-E-L-A-T-V-R-T-I-C-S-H-V-Q-N-M-I-K-G-V-T-L-G-F-R-Y-K-M-R-S-V-Y-A-H-F-P-I-N-V-V-I-Q-E-T-G-S-L-V-E-I-R-N-F-L-G-E-K-Y-I-R-R-V-R-M-R-P-G-V-N-C-A-L-S-A-A-Q-K-D-E-L-V-L-E-G-N-D-I-E-L-V-S-N-S-A-A-L-I-Q-Q-A-T-T-V-K-N-K-D-I-R-K-F-L-D-G-I-Y-V-S-E-K-G-T-V-V-E-P-E-S


### FUNCTION May have role in testicular activity ### SEQUENCE -M-S-D-T-S-V-D-A-S-V-E-K-T-T-K-D-L-K-S-K-D-K-E-L-V-E-E-T-E-N-G-K-D-K-P-A-N-G-N-A-E-N-E-E-N-G-E-D-G-A-D-N-E-E-E-E-E-V-D-E-E-D-E-E-D-E-G-E-G-D-D-D-E-G-D-E-D-D-E-A-D-G-A-T-G-K-R-A-A-E-D-D-D-E-D-D-D-V-D-A-K-K-Q-K-T-D-D-D-D


### FUNCTION Has antimicrobial activity ### SEQUENCE -M-A-S-L-K-K-S-L-F-L-V-L-F-L-G-L-V-S-L-S-I-C-E-E-E-K-R-E-N-E-D-E-E-E-Q-E-D-D-E-Q-S-E-M-K-R-G-L-W-S-N-I-K-T-A-G-K-E-A-A-K-A-A-L-K-A-A-G-K-A-A-L-G-A-V-T-D-A-V-G-E-Q


### FUNCTION Has antimicrobial activity ### SEQUENCE -M-A-F-L-K-K-S-L-F-L-V-L-F-L-G-L-V-S-L-S-I-C-E-E-E-K-R-E-N-E-D-E-E-E-Q-E-D-D-E-Q-S-E-M-K-R-G-L-W-S-K-I-K-E-A-G-K-A-A-L-T-A-A-G-K-A-A-L-G-A-V-S-D-A-V-G-E-Q


### FUNCTION Antimicrobial peptide ### SEQUENCE -M-K-F-T-A-T-F-L-M-M-F-I-F-V-L-M-V-E-P-G-E-C-G-W-G-S-I-F-K-H-G-R-H-A-A-K-H-I-G-H-A-A-V-N-H-Y-L-G-E-Q-Q-D-L-D-K-R-A-V-D-E-D-P-N-V-I-V-F-E


### FUNCTION Plays an important role in catfish calcium homeostasis ### SEQUENCE -M-S-D-L-Q-K-G-M-A-L-L-I-S-T-F-H-K-Y-S-G-K-E-G-D-K-C-T-L-T-K-G-E-L-K-D-L-L-T-K-E-L-G-G-A-F-G-N-C-S-D-Q-A-T-L-D-K-I-F-K-D-L-D-T-N-A-D-G-V-V-D-F-Q-E-Y-A-T-M-V-A-C-T-T-M-L-C-N-K-S-L-S-K-K


### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-D-S-N-T-V-S-S-F-Q-D-I-L-L-R-M-S-K-M-Q-L-G-S-S-S-E-D-L-N-G-M-I-T-Q-F-E-S-L-K-L-Y-R-D-S-L-G-E-A-V-M-R-M-G-D-L-H-S-L-Q-N-R-N-G-K-W-R-E-Q-L-G-Q-K-F-E-E-I-R-W-L-I-E-E-V-R-H-R-L-K-T-T-E-N-S-F-E-Q-I-T-F-M-Q-A-L-Q-L-L-F-E-V-E-Q-E-I-R-T-F-S-F-Q-L-I


### FUNCTION Has low cytotoxic activity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-H-N-T-Q-L-P-F-I-Y-K-T-C-P-E-G-K-N-L-C-F-K-A-T-L-K-K-F-P-L-K-F-P-V-K-R-G-C-A-D-N-C-P-K-N-S-A-L-L-K-Y-V-C-C-S-T-E-K-C-N


### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1  with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-A-A-A-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-K-L-I-P-I-A-S-K-T-C-P-A-G-M-N-L-C-Y-K-M-F-M-M-S-D-L-T-I-P-V-K-R-G-C-I-D-V-C-P-K-N-S-L-L-V-K-Y-V-C-C-N-T-D-R-C-N


### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1  with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-K-L-I-P-I-A-S-K-T-C-T-A-G-K-N-L-C-Y-K-M-F-M-M-S-D-L-T-I-P-V-K-R-G-C-I-D-V-C-P-K-N-S-L-L-V-K-Y-V-C-C-N-T-D-R-C-N


### FUNCTION Has low cytotoxic activity ### SEQUENCE -M-K-T-L-L-L-T-M-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-H-N-T-Q-L-P-F-I-Y-K-T-C-P-E-G-K-N-L-C-F-K-A-T-L-K-K-F-P-L-K-F-P-V-K-R-G-C-A-D-N-C-P-K-N-S-A-L-L-K-Y-V-C-C-S-S-D-K-C-N


### FUNCTION Isotocin causes contraction of smooth muscles ### SEQUENCE -M-T-G-A-A-V-S-V-C-L-L-Y-A-L-S-V-C-S-A-C-Y-I-S-N-C-P-I-G-G-K-R-S-I-M-D-A-P-Q-R-K-C-M-S-C-G-P-G-E-Q-G-R-C-F-G-P-S-I-C-C-G-K-D-V-G-C-W-M-G-S-P-E-T-A-H-C-M-E-E-N-Y-L-P-T-P-C-Q-V-G-G-R-P-C-G-S-D-T-V-R-C-A-S-P-G-V-C-C-D-S-E-G-C-S-A-D-Q-S-C-F-A-E-E-E-G-D-N-Q-I-G-Q-S-E-G-S-N-S-A-D-V-I-L-R-L-L-H-L-A-D-H-T-P-P-H-R-V-H-Q


### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-R-R-Q-A-S-L-P-A-R-R-R-R-R-V-R-R-T-R-V-V-R-R-R-R-R-V-G-R-R-R-H


### FUNCTION Contributes to the transparency and refractive index of the lens May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions ### SEQUENCE -M-D-I-A-I-Q-H-P-W-F-K-R-A-L-G-P-F-Y-P-N-R-L-F-D-Q-V-F-G-E-G-M-F-D-Y-D-L-F-P-F-L-S-S-T-V-S-P-Y-Y-R-H-S-L-F-R-G-F-M-D-S-G-I-S-E-V-R-S-D-R-D-R-F-T-I-N-L-D-V-K-H-F-S-P-D-D-L-T-V-K-I-L-D-D-F-V-E-I-H-G-K-H-S-E-R-Q-D-D-H-G-Y-I-S-R-E-F-H-R-R-Y-R-L-P-S-N-L-D-Q-S-S-I-S-C-S-L-S-A-D-G-I-L-T-F-S-G-P-K-M-M-S-G-L-D-S-S-H-S-E-R-P-I-P-V-S-R-E-E-K-P-T-S-A-P-S-S


### FUNCTION Crystallins are the dominant structural components of the vertebrate eye lens ### SEQUENCE -M-G-K-I-I-F-Y-E-D-R-N-F-Q-G-R-S-Y-E-C-S-N-D-N-P-D-L-Q-P-N-F-N-A-C-N-S-V-R-V-E-N-G-C-W-M-I-Y-E-R-P-N-Y-M-G-H-P-Y-F-L-K-R-G-E-Y-P-D-Y-Q-Q-C-Q-G-L-N-D-S-I-R-S-S-R-L-L-S-Q-N-L-G-I-G-T-N-K-L-R-V-Y-E-R-G-D-S-K-G-E-M-M-E-F-L-E-D-C-P-N-V-Y-D-R-F-C-S-H-E-I-H-S-C-N-V-L-D-G-Y-W-I-F-Y-E-L-P-N-Y-K-G-K-Q-Y-L-L-R-P-G-E-Y-K-R-F-T-D-W-G-S-Q-T-A-K-V-G-S-F-R-R-V-I-D-I-C


### FUNCTION Crystallins are the dominant structural components of the vertebrate eye lens ### SEQUENCE -M-G-K-I-I-F-Y-E-D-R-N-F-Q-G-R-S-Y-E-C-S-N-D-N-P-D-L-Q-P-N-F-N-A-C-N-S-V-R-V-E-N-G-C-W-M-I-Y-E-R-P-N-Y-M-G-H-Q-Y-F-L-K-R-G-E-Y-P-D-Y-Q-Q-C-Q-G-L-N-D-S-P-Q-S-S-R-L-L-S-Q-N-L-G-I-G-T-N-K-L-R-V-Y-E-R-G-D-S-K-G-E-M-M-E-F-L-E-D-C-P-N-V-Y-D-R-F-C-S-H-E-I-H-S-C-N-V-L-D-G-Y-W-I-F-Y-E-L-P-N-Y-K-G-K-Q-Y-L-L-R-P-G-E-Y-K-R-F-T-D-W-G-S-Q-T-A-K-V-G-S-F-R-R-V-I-G-I-C


### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-V-H-I-C-R-L-L-V-L-M-G-M-L-L-C-L-S-A-Q-F-A-S-S-Q-H-W-S-H-G-W-Y-P-G-G-K-R-E-I-D-I-Y-D-T-S-E-V-S-G-E-I-K-L-C-E-A-G-K-C-S-Y-L-R-P-Q-G-R-N-I-L-K-T-I-L-L-D-A-L-I-R-D-F-Q-K-R-K


### FUNCTION Small multifunctional phosphoprotein involved in virion morphogenesis, egress and counteracting host innate immunity ### SEQUENCE -M-C-L-S-C-Q-F-W-C-L-E-C-Q-E-S-G-V-G-C-R-C-V-D-C-C-S-C-L-Q-C-A-A-G-C-Q-G-A-P-K-R-S-Q-P-E-A-G-V-A-S-A-A-V-T-I-Q-P-S-G-A-L-N-N-A-P-R-E-P-S-A-P-P-L-S-Q-T-L-S-P-R-Q-V-L-A-R-Y-Q-M


### FUNCTION In muscle, parvalbumin is thought to be involved in relaxation after contraction It binds two calcium ions ### SEQUENCE -M-A-C-A-H-L-C-K-E-A-D-I-K-T-A-L-E-A-C-K-A-A-D-T-F-S-F-K-T-F-F-H-T-I-G-F-A-S-K-S-A-D-D-V-K-K-A-F-K-V-I-D-Q-D-A-S-G-F-I-E-V-E-E-L-K-L-F-L-Q-N-F-C-P-K-A-R-E-L-T-D-A-E-T-K-A-F-L-K-A-G-D-A-D-G-D-G-M-I-G-I-D-E-F-A-V-L-V-K-Q


### FUNCTION Contributes to the transparency and refractive index of the lens May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions ### SEQUENCE -R-A-L-G-P-L-F-P-S-R-L-F-D-Q-Y-L-G-E-G-L-F-D-Y-D-L-L-P-F-F-S-S-T-I-S-P-Y-Y-R-H-S-L-F-R-T-V-L-E-S-G-I-S-E-V-R-S-D-R-D-K-F-T-I-L-L-D-V-K-H-F-S-P-E-D-L-S-V-K-I-M-D-D-F-V-E-I-H-G-K-H-N-E-R-Q-D-D-H-G-Y-I-S-R-E-F-H-R-R-Y-R-L-P-S-N-V-D-Q-S-A-I-T-C-S-L-S-A-D-G-M-L-T-F-S-G-P-K-V-Q-S-N-M-D-T-S-Y-S-E-R-P-I-P


### FUNCTION May contribute to the transparency and refractive index of the lens ### SEQUENCE -L-I-R-R-P-L-F-S-F-L-T-P-T-R-I-F-D-Q-S-F-G-E-H-L-S-E-S-E-L-F-P-T-S-G-A-L-S-P-F-L-L-R-S-P-F-L-R-T-P-S-W-L


### FUNCTION Transcriptional regulator Involved in the initiation of neuronal differentiation Activates transcription by binding to the E box-containing promoter ### SEQUENCE -R-D-D-F-S-S-D-D-M-K-S-D-D-E-S-S-Q-K-E-M-K-S-S-R-G-R-T-S-S-I-N-E-D-E-D-L-N-P-E-Q-K-V-E-R-E-K-E-R-R-M-A-N-N-A-R-E-R-L-R-V-R-D-I-N-E-A-F-K-E-L-G-R-M-C-Q-L-H-L-K-S-E-K-P-Q-T-K-L-L-I-L-H-Q-A-V-A-V-I-L-N-L-E-Q-Q-V-R-E-R-N-L-N-P-K-A-A-C-L-K-R-R-E-E-E-K-V-S-A-V-S-A-E-P-P-N-T-H-P-G-V-H-P-G-L-T-D-T-T-N-P-M-G-H-M


### FUNCTION Transcriptional activator ### SEQUENCE -M-S-V-F-Y-P-I-H-C-T-D-Y-L-R-S-A-E-M-T-E-V-I-M-N-T-Q-S-M-D-E-I-G-L-S-P-R-K-D-S-Y-Q-I-F-P-D-P-S-D-F-E-R-C-C-K-L-K-D-R-L-P-S-I-V-V-E-P-T-E-G-D-V-E-S-G-E-L-R-W-P-P-E-E-F-V-V-D-E-D-K-E-G-T-C-D-Q-T-K-K-E-N-E-Q


### FUNCTION Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function ### SEQUENCE -M-S-Y-K-N-I-Y-Y-S-D-K-Y-T-D-E-H-F-E-Y-R-H-V-M-L-P-K-E-L-A-K-Q-V-P-K-T-H-L-M-S-E-E-E-W-R-R-L-G-V-Q-Q-S-L-G-W-V-H-Y-M-I-H-E-P-E-P-H-I-L-L-F-R-R-P-L-P-K-D-Q-Q-K


### FUNCTION Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments ### SEQUENCE -M-H-Y-I-D-W-V-I-L-L-T-F-A-A-A-L-I-V-C-L-T-P-K-P-E-P-C-I-I-T-V-S-G-A-S-A-T-V-S-N-C-P-N-P-E-L-L-T-D-L-V-K-A-L-K-P-A-K-P-V


### FUNCTION Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata, ### SEQUENCE -M-P-L-Q-P-P-P-D-H-T-W-A-V-R-I-I-A-L-G-L-A-V-T-A-L-I-F-T-S-T-R-D-T-S-R-H-V-G-D-P-S-H-S-L-P-F-G-G-H-Y-R-D-G-S-K-V-I-H-Y-N-S-P-R-S-S-K-P-S-N-H-T-P-Y-L-L-F-A-P-I-G-I-I-L-L-I-H-A-L-H-R-L-G-N-S-A-H-I-C-R-C-T-H-C-M-P-H-S-Q-T


### FUNCTION Has low cytotoxic activity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-H-N-T-Q-L-P-F-I-Y-K-T-C-P-E-G-K-N-L-C-F-K-A-T-L-K-K-F-P-L-K-F-P-V-K-R-G-C-A-D-N-C-P-K-N-S-A-L-L-K-Y-V-C-C-S-T-D-K-C-N


### FUNCTION Component of the DNA-dependent RNA polymerase that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates ### SEQUENCE -M-F-S-K-S-Y-Q-I-T-K-E-M-Y-E-A-R-G-W-Q-I-I-K-E-D-E-L-T-I-L-A-K-V-N-S-R-E-N-T-N-P-E-F-A-I-A-K-F-I-K-T-T-Q-E-I-K-S-P-P-L-S-Q-I-I-D-F-S-S-N-E-Y-V-C-V-T-I-I-C-D-G-S-I-T-T-N-V-K-K-I-E-Q-T-T-K-G-K-V-E-I-F-H-N-K-D-L-Q-M-N-I-T-K-Y-H-L-Q-P-L-F-N-K-L-L-D-E-E-A-K-D-F-K-K-K-Y-I-K-C-K-I-E-N-G-K-K-I-I-L-Q-S-F-P-S-M-S-K-S-D-P-I-A-R-F-F-K-Y-Q-S-G-D-V-I-K-I-T-N-K-D-G-F-V-S-Y-R-I-V-K


### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-Y-Q-Q-K-Y-F-E-K-P-V-Y-Y-L-Q-R-N-D-F-D-D-N-G-N-L-I-V-P-E-L-R-N-K-K-V-I-I-M-I-Q-A-N-Y-C-G-H-C-T-N-A-K-G-D-Y-Y-K-A-A-K-Y-I-K-E-L-E-K-N-G-G-T-S-Y-K-N-K-V-V-F-A-T-I-Q-A-D-G-D-E-E-G-E-K-E-L-N-Q-I-L-D-K-I-K-P-T-F-V-G-F-P-D-Y-V-L-Y-V-N-G-K-R-I-E-D-D-G-P-P-G-R-N-F-N-N-I-V-N-Y-V-M-G


### FUNCTION May function as a phosphatase ### SEQUENCE -M-K-N-I-F-L-D-L-D-N-T-L-I-C-A-E-P-F-E-D-I-T-D-L-G-R-F-K-E-R-A-S-H-F-D-F-K-N-M-E-D-Y-Y-L-I-C-G-R-P-Y-L-Q-P-F-L-D-Y-L-F-K-N-F-N-V-H-I-W-T-A-A-S-K-G-Y-A-S-F-I-I-E-E-F-I-L-K-K-D-P-S-R-K-I-N-L-V-L-F-D-H-H-C-R-V-S-K-R-V-Y-K-K-E-K-A-S-K-K-L-E-M-L-W-T-I-W-K-L-Q-E-F-D-K-E-N-T-F-I-I-D-D-L-E-E-V-K-E-S-Q-V-K-N-C-F-S-V-K-P-F-F-F-M-E-N-D-S-E-Y-D-Q-E-L-M-R-L-K-D-V-L-N-R-H-L-N


### FUNCTION FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation ### SEQUENCE -M-T-D-I-D-P-H-I-W-G-P-S-F-W-S-T-Y-H-L-Y-A-S-S-Y-P-I-H-P-T-P-I-I-M-D-A-A-R-S-F-V-K-T-I-P-F-T-L-P-C-S-S-C-T-D-H-A-F-A-Y-I-K-N-I-Q-K-Q-D-P-D-L-I-S-I-V-S-S-K-M-L-F-E-K-F-F-I-D-F-H-N-S-V-N-Y-R-L-G-K-P-L-L-P-E-S-V-A-R-K-K-W-R-F


### FUNCTION Probably involved in the viral transport within, and between cells ### SEQUENCE -M-M-V-C-L-P-D-W-L-F-L-L-F-I-F-S-I-L-L-Q-S-G-T-N-F-Y-G-T-F-Q-S-G-S-I-S-R-Q-L-S-S-L-S-S-S-I-D-Q-L-F-L-K-V-Q-Q-V-V-Y-T-R-Y-P-S-R-D-R-V-S-D-P-R-R-R-R-G-L-S-S-I-P-E-G-S-E-E-A-T-E-V


### FUNCTION Superoxide dismutase-like protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-G-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-R-G-C-E-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-F-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V


### FUNCTION Superoxide dismutase-like protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-R-G-C-D-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-Y-I-N-E-K-N-N-T-F-S-Y-N


### FUNCTION Superoxide dismutase-like protein with no enzymatic activity ### SEQUENCE -M-A-V-C-I-I-D-H-D-N-I-R-G-V-I-Y-F-E-P-V-H-G-K-D-K-V-L-G-S-V-I-G-L-K-S-G-T-Y-S-L-I-I-H-R-Y-G-D-I-S-R-G-C-D-S-I-G-S-P-E-I-F-I-G-N-I-F-V-N-R-Y-G-V-A-Y-V-Y-L-D-T-D-V-N-I-S-T-I-I-G-K-A-L-S-I-S-K-N-D-Q-R-L-A-C-G-V-I-G-I-S-Y-I-N-E-K-I-I-H-F-L-T-I-N-E-N-G-V


### FUNCTION Involved in the viral transport within, and between cells ### SEQUENCE -M-D-P-Q-S-A-I-Y-T-L-P-R-V-P-T-A-A-P-T-T-G-G-V-S-W-S-H-V-G-E-V-A-I-L-S-F-V-A-L-I-C-I-Y-L-L-Y-L-W-V-L-R-D-L-I-L-V-L-K-A-R-R-G-R-S-T-E-E-L-I-F-G-S-E-A-V-D-R-R-H-P-I-P-N-T-L-V-P-T-A-P-V-H-P-G-P-F-V-P-G-Q-G


### FUNCTION Involved in the viral transport within, and between cells ### SEQUENCE -M-D-P-Q-S-A-V-Y-S-L-P-R-V-P-T-A-A-P-P-N-A-G-V-P-W-S-H-V-G-E-V-A-V-L-S-F-V-A-L-I-C-I-Y-L-L-Y-L-W-V-L-R-D-L-I-L-V-L-K-A-R-R-G-R-S-T-E-E-L-I-F-G-S-E-A-V-D-R-R-S-P-I-P-N-T-L-E-P-T-A-P-V-H-P-G-P-F-V-P-G-S-G


### FUNCTION Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme ### SEQUENCE -M-A-N-S-L-R-G-E-V-L-T-L-Y-K-N-L-L-Y-L-G-R-D-Y-P-K-G-A-D-Y-F-K-R-R-L-K-N-V-F-L-K-N-K-D-V-E-D-P-E-K-I-K-E-L-I-A-R-G-E-F-V-M-K-E-L-E-A-L-Y-F-L-R-K-Y-R-A-M-K-Q-R-Y-Y-S-D-T-K-V


### FUNCTION May activate the NF-kappa-B signaling pathway ### SEQUENCE -M-V-C-I-P-C-I-V-I-P-V-L-L-W-I-F-K-K-F-L-E-P-Y-I-Y-P-V-V-S-R-I-W-P-K-K-A-V-Q-Q-S-G-D-K-N-M-S-K-V-D-C-K-G-A-G-T-N-G-L-P-T-K-G-P-T-E-V-S-D-K-K-K-D


### FUNCTION Has an antimicrobial activity ### SEQUENCE -S-V-V-L-L-I-C-L-L-L-L-G-Q-V-D-G-S-P-V-P-E-K-S-S-V-K-K-R-L-R-R-M-T-P-F-W-R-G-V-S-L-R-P-I-G-A-S-C-R-D-D-S-E-C-I-T-R-L-C-K-K-R-R-C-S-L-S-V-A-Q-E


### FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals ### SEQUENCE -M-D-P-C-E-C-S-K-T-G-K-C-N-C-G-T-S-C-T-C-T-N-C-S-C-K-C-C-K-K-S-C-C-S-C-C-P-S-G-C-S-K-C-A-S-G-C-V-C-K-G-N-S-C-D-K-S-C-C-Q


### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -V-R-V-V-V-L-A-L-V-A-Q-V-T-L-S-Q-H-W-S-Y-G-W-L-P-G-G-K-R-S-V-G-E-L-E-A-T-I-K-M-M-D-T-G-G-V-V-A-L-P-E-E-T-S-A-H-V-S-E-R-L-R-P-Y-D-V-I-L-K-K-W-M-P-H-K


### FUNCTION Stimulates the secretion of gonadotropins ### SEQUENCE -M-E-W-K-G-R-V-L-V-Q-L-L-M-L-V-C-V-L-E-V-S-L-C-Q-H-W-S-Y-G-W-L-P-G-G-K-R-S-V-G-E-V-E-A-T-I-R-M-M-D-G-G-D-T-L-L-S-I-P-A-D-T-P-M-E-Q-L-S-P-I-H-I-M-N-E-V-D-A-E-G-F-P-L-K-E-Q-R-F-P-N-R-R-G-R-M


### FUNCTION May be involved in transcriptional regulation Modulates various viral and cellular promoters in a promoter context-dependent manner Does not bind DNA directly ### SEQUENCE -M-E-N-T-R-S-E-N-E-E-Q-P-E-S-T-L-K-I-D-E-E-Q-P-A-V-E-Q-S-P-E-N-Q-C-S-E-E-D-Q-S-S-E-D-L-S-S-E-E-Q-S-S-E-E-E-F-F-P-E-E-L-L-P-E-L-L-P-E-M-L-L-S-E-D-R-P-P-Q-E-C-L-S-Q-K-N-Q-F-E-D-R-I-P-M-E-Q-P-P-C-G-V-G-K-H-K-L-E-E-G-S-F-K-E-R-L-A-R-I-R-P-Q-F-I-G-D-I-H-G-R-N-L-S-N-E-E-M-I-Q-A-A-D-E-L-E-E-M-K-R-V-R-N-K-L-M-I-M-H-W-K-A-K-R-S-R-P-Y-P-I


### FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell The small ribosomal subunit , which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel ### SEQUENCE -M-A-P-G-L-V-V-G-L-N-K-G-K-V-L-T-K-R-Q-L-P-E-R-P-S-R-R-K-G-Q-L-S-K-R-T-S-F-V-R-S-I-V-R-E-V-A-G-F-A-P-Y-E-R-R-V-M-E-L-I-R-N-S-Q-D-K-R-A-R-K-L-A-K-K-R-L-G-T-L-K-R-A-K-G-K-I-E-E-L-T-S-V-I-Q-S-S-R-L-A-H


### FUNCTION Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems ### SEQUENCE -M-A-H-V-L-P-D-L-P-Y-A-Y-N-A-L-E-P-F-I-S-Q-Q-I-M-E-L-H-H-K-K-H-H-Q-T-Y-V-N-S-L-N-A-A-E-Q-A-Y-A-K-A-S-T-P-K-E-R-I-A-L-Q-S-A-L-K-F-N-G-G-G-H-I-N-H-S-L-F-W-K-N-L-A-P-A-K-S-E-G-K-G-N-G-G-A-L-A-D-G-P-L-K-S-A-I-E-Q-N-W-G-S-V-D-N-F-I-K-E-F-N-A-T-T-A-A-I-Q-G-S-G-W-G-W-L-G-L-N-P-A-T-K-R-L-E-I-T-T-T-A-N-Q-D-P-L-L-S-H-V-P-I-I-G-V-D-I-W-E-H-A-F-Y-L-Q-Y-L-N-V-K-A-D-Y-L-A-A-I-W-I-V-I-N-F-K-E-A-E-R-R-L-I-E-A-T-K


### FUNCTION Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair ### SEQUENCE -M-S-K-Q-P-I-S-N-V-R-S-I-Q-A-N-I-N-I-P-M-G-A-F-R-P-G-A-G-Q-P-P-R-R-K-E-S-T-P-G-T-A-E-G-A-P-A-T-P-E-E-K-K-P-V-P-G-M-K-K-F-P-G-P-V-V-N-L-S-E-I-Q-N-V-K-S-E-L-K-Y-V-P-K-G-E-Q


### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-Y-Y-S-G-Y-S-G-G-L-G-Y-G-Y-G-S-S-F-G-G-P-G-C-G-C-N-S-I-R-R-L-G-C-G-S-G-Y-G-G-F-G-Y-G-S-G-Y-G-G-Y-G-Y-G-S-D-Y-G-G-Y-G-Y-G-S-S-Y-G-G-Y-G-C-G-C-R-R-P-S-C-C-G-R-Y-G-F-S-N-F-Y


### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-C-G-Y-Y-G-N-Y-Y-G-G-R-G-Y-G-C-C-G-C-G-G-L-G-Y-G-Y-G-G-L-G-C-G-Y-G-S-Y-Y-G-C-G-Y-R-G-L-G-C-G-Y-G-Y-G-C-G-Y-G-S-R-S-L-Y-G-C-G-Y-G-C-G-S-G-Y-G-S-G-F-G-Y-Y-Y


### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-H-Y-S-S-Y-Y-G-G-L-G-Y-G-Y-G-S-F-G-G-P-G-C-G-C-N-S-I-R-R-L-V-G-F-G-S-G-Y-G-G-F-G-Y-G-S-G-F-G-G-F-G-Y-G-S-G-Y-G-G-Y-G-Y-G-S-G-F-R-G-Y-G-C-G-C-R-R-P-S-C-C-G-G-Y-G-F-S-S-F-Y


### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-Y-Y-N-S-Y-Y-G-G-L-G-Y-G-S-G-G-Y-G-G-L-G-Y-G-Y-G-C-G-C-G-S-F-R-R-L-G-Y-G-C-G-F-G-G-Y-G-G-F-G-Y-G-S-G-Y-G-G-F-S-S-G-S-G-Y-G-G-F-G-Y-G-Y-R-R-P-L-S-Y-G-G-Y-G-F-S-T-F-Y


### FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins , which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins ### SEQUENCE -M-S-Y-Y-S-G-Y-S-G-G-L-G-Y-G-Y-G-S-S-F-G-G-L-G-C-G-C-N-S-I-R-R-L-G-C-G-S-G-Y-G-G-F-G-Y-G-S-G-Y-G-G-F-G-G-F-G-Y-G-S-G-Y-G-G-Y-G-Y-G-S-G-Y-G-G-F-G-G-F-G-Y-G-S-G-Y-G-G-F-G-Y-G-S-G-Y-G-G-F-G-G-F-G-Y-G-S-G-Y-G-G-Y-G-Y-G-S-G-F-G-G-Y-G-Y-G-S-G-F-R-G-Y-G-C-G-C-R-R-S-S-C-C-G-G-Y-G-F-S-S-F-Y


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-K-E-A-T-R-V-R-R-R-E-R-K-N-I-T-S-G-V-A-H-V-N-S-S-F-N-N-T-M-I-T-I-T-D-A-Q-G-N-A-I-A-W-S-S-A-G-A-K-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-I-A-A-E-D-C-A-K-K-A-Q-E-H-G-M-K-S-L-E-V-E-V-C-G-P-G-S-G-R-E-S-A-L-R-A-L-Q-A-A-G-F-M-I-T-S-I-R-D-V-T-P-I-P-H-N-G-C-R-P-R-K-K-R-R-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-T-A-K-R-V-V-I-A-L-T-Y-I-H-G-I-G-T-K-F-A-Q-E-I-I-E-K-V-G-I-P-A-E-R-R-V-H-Q-L-T-D-A-E-V-L-Q-I-R-E-T-I-D-R-D-Y-Q-V-E-G-D-L-R-R-E-T-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-H-T-N-A-R-T-R-K-G-P-A-K-A-I-A-G-K-K-K


### FUNCTION Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity ### SEQUENCE -M-S-R-I-D-T-P-A-A-S-R-M-Q-T-I-A-R-N-P-V-M-I-A-L-V-M-T-L-A-L-A-G-C-A-S-K-K-N-L-P-N-D-A-A-G-L-G-L-G-A-G-A-A-T-P-G-S-Q-Q-D-F-T-V-N-V-G-D-R-I-F-F-D-T-D-S-T-S-I-R-A-D-A-Q-A-T-L-D-R-Q-A-Q-W-L-A-K-Y-P-N-Y-G-I-T-I-E-G-H-A-D-E-R-G-T-R-E-Y-N-L-A-L-G-A-R-R-A-A-A-T-R-D-Y-L-V-S-R-G-V-P-G-N-R-M-R-T-I-S-Y-G-K-E-K-P-V-A-V-C-D-D-I-S-C-W-S-Q-N-R-R-A-V-T-V-L-G-G-A-G-S


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-K-Y-R-I-K-K-N-D-D-F-Q-K-V-F-R-R-G-K-S-F-A-N-R-Q-F-V-V-Y-T-L-K-Q-E-E-A-S-H-F-R-I-G-L-S-V-S-K-K-I-G-N-A-V-C-R-N-R-I-K-R-Y-I-R-Q-S-F-H-E-L-E-S-Q-I-N-P-E-N-E-Y-I-I-I-A-R-K-P-A-A-N-M-D-F-H-E-V-K-K-S-L-I-H-V-L-K-V-G-R-V-L-K-Q-K-P-N-N-S-K


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-R-G-M-G-N-M-Q-G-M-M-K-Q-M-Q-K-M-Q-K-E-M-A-K-A-Q-A-D-L-E-A-Q-E-F-T-G-T-A-G-G-G-M-V-T-V-K-A-I-G-K-R-V-I-T-D-V-V-I-N-E-E-V-V-D-P-E-D-I-E-M-L-Q-D-L-V-L-A-A-T-N-D-V-L-K-Q-I-E-D-T-T-S-Q-T-M-G-K-F-T-Q-G-L-N-L-P-G-M


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-H-Y-P-E-P-I-T-K-L-M-D-S-F-M-K-L-P-G-I-G-P-K-S-A-A-R-L-A-F-Y-V-L-D-M-K-E-D-D-V-L-D-F-A-K-A-L-V-D-A-K-R-N-L-S-F-C-S-V-C-G-H-I-T-D-K-D-P-C-Y-I-C-S-D-T-S-R-D-R-S-V-L-C-V-V-Q-E-S-K-D-V-I-A-M-E-K-M-R-D-F-H-G-L-Y-H-V-L-H-G-T-I-S-P-M-D-G-I-G-P-E-D-I-N-I-P-D-L-L-K-R-L-Q-D-D-T-I-E-E-V-I-L-A-T-N-P-N-V-E-G-E-A-T-A-M-Y-I-S-R-L-L-R-P-S-G-I-K-V-T-R-I-A-H-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-S-K-A-M-E-G-R-R-E-V


### FUNCTION Part of the high-affinity ATP-driven potassium transport  system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-K-R-F-M-Q-I-W-K-P-A-V-V-G-F-L-L-L-T-L-V-C-G-V-I-Y-P-G-V-V-T-I-I-A-G-A-A-F-Q-D-K-A-N-G-S-I-I-E-G-K-L-A-D-G-E-T-G-K-Y-G-S-T-E-I-G-Q-T-F-T-Q-P-E-Y-L-I-G-R-A-A-S-D-G-A-A-T-N-L-N-P-T-S-E-E-Q-K-Q-L-V-E-K-R-I-T-W-W-H-K-L-D-P-A-N-N-R-V-I-P-M-D-L-V-T-A-S-A-S-G-V-D-P-D-I-S-E-A-A-A-A-Y-Q-V-D-R-I-S-R-E-R-G-I-S-T-K-V-V-K-E-I-I-A-E-N-T-S-K-R-L-L-G-F-W-G-E-P-T-V-N-V-L-Q-V-N-V-A-L-D-S-L-K-M


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-D-A-R-D-I-I-K-R-P-V-V-T-E-E-S-T-S-I-L-D-D-K-K-Y-T-F-E-V-D-T-R-A-T-K-T-Q-V-K-Y-A-I-E-E-I-F-D-V-K-V-A-K-V-N-V-M-N-Y-K-G-K-L-K-R-M-G-R-Y-A-G-Y-T-N-K-R-R-K-A-I-V-T-V-T-A-D-S-K-E-I-Q-F-F-E-V


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-S-E-V-T-S-A-K-A-V-A-K-T-V-R-I-A-P-R-K-A-R-I-V-I-D-L-I-R-G-K-Q-V-G-E-A-I-A-I-L-K-Y-T-P-R-S-A-S-P-I-I-E-K-V-L-K-S-A-I-A-N-A-E-H-N-Y-D-L-D-I-N-N-L-V-V-E-E-A-F-V-D-E-G-P-T-L-K-R-F-R-P-R-A-Q-G-R-A-S-A-I-N-K-R-T-S-H-I-T-V-V-V-S-E-V-K-E-G


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-Y-R-R-E-F-R-G-N-M-R-G-R-A-K-G-G-T-E-V-A-F-G-E-Y-G-L-Q-A-V-E-A-S-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-S-K-P-I-G-V-R-M-G-K-G-K-G-A-P-E-G-W-V-S-P-V-K-R-G-K-I-M-F-E-I-A-G-V-P-E-D-V-A-R-E-A-L-R-L-A-A-H-K-L-P-V-K-T-K-I-V-K-R-E-E-I-G-G-E-A-N-E-S


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-D-R-N-Q-R-K-V-Y-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-Y-K-K-H-G-L-Y-G-K-R-V-K-Y-S-K-K-F-K-A-H-D-E-N-N-I-A-K-T-G-D-V-V-R-I-S-E-T-R-P-L-S-A-T-K-H-F-R-L-L-E-V-V-E-E-A-V-I-I


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-M-K-V-A-D-N-S-G-A-R-E-V-L-T-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-V-V-V-C-T-V-K-Q-A-T-P-G-G-V-V-K-K-G-E-V-V-K-A-V-I-V-R-T-K-S-G-A-R-R-Q-D-G-S-Y-I-K-F-D-E-N-A-C-V-I-I-R-D-D-K-S-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-N-N-F-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-H-V-K-K-G-D-K-V-K-V-I-T-G-K-D-K-G-K-S-G-K-V-L-A-A-F-P-K-K-D-R-V-L-I-E-G-I-N-M-V-K-K-H-T-K-P-S-N-I-N-P-Q-G-G-I-L-N-V-E-A-P-I-H-V-S-N-V-M-L-I-D-P-K-T-G-E-P-T-R-V-G-Y-E-V-K-G-D-K-K-V-R-V-A-K-K-S-G-E-V-I-D-K


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-N-R-L-K-D-Q-Y-L-K-E-I-V-P-A-L-M-S-K-F-N-Y-D-S-V-M-E-V-P-K-I-D-K-I-V-I-N-T-G-V-G-D-A-T-A-N-A-K-V-L-D-S-A-V-E-E-L-A-L-I-T-G-Q-K-P-V-I-T-K-A-K-N-S-I-A-G-F-R-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-E-R-M-Y-D-F-L-D-K-L-V-T-V-S-L-P-R-V-R-D-F-R-G-V-S-K-K-A-F-D-G-R-G-N-Y-T-L-G-V-R-E-Q-L-I-F-P-E-I-D-Y-D-Q-V-S-K-V-R-G-M-D-V-V-I-V-T-T-A-K-S-D-E-E-S-H-E-L-L-T-Q-L-G-M-P-F-Q-K


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-K-T-I-V-I-P-A-G-V-T-V-T-L-N-G-S-T-A-T-V-K-G-P-K-G-E-L-V-K-E-F-N-P-E-I-T-I-N-I-E-G-N-E-I-N-V-S-R-P-T-D-N-K-N-H-R-A-L-H-G-T-T-R-A-I-L-N-N-M-V-V-G-V-S-E-G-Y-E-K-K-L-E-L-I-G-V-G-Y-R-A-Q-K-Q-G-D-K-L-V-L-N-V-G-Y-S-H-P-V-E-F-V-A-P-K-G-V-E-I-E-V-P-A-N-T-Q-V-I-V-K-G-Y-N-K-E-H-V-G-E-L-A-A-N-I-R-A-V-R-P-P-E-P-Y-K-G-K-G-I-R-Y-E-G-E-H-V-R-R-K-E-G-K-T-G-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-T-K-I-D-K-N-K-V-R-K-K-R-H-A-R-V-R-S-K-I-S-G-T-E-S-R-P-R-L-N-V-F-R-S-N-K-N-I-Y-A-Q-V-I-D-D-V-N-G-V-T-L-A-S-A-S-N-L-D-K-D-F-G-S-A-E-S-K-V-D-A-A-S-K-V-G-E-L-V-A-K-R-A-S-E-K-G-I-T-S-V-T-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-E-A-A-R-E-N-G-L-E-F


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-P-E-Q-I-D-G-N-K-L-D-L-E-E-R-V-V-T-I-N-R-V-A-K-V-V-K-G-G-R-R-F-R-F-T-A-L-V-V-V-G-D-K-N-G-H-V-G-F-G-T-G-K-A-Q-E-V-P-D-A-I-R-K-A-V-E-D-A-K-K-N-M-V-F-V-P-T-V-D-T-T-I-P-H-T-V-V-G-H-F-G-G-G-E-I-L-L-K-P-A-S-A-G-S-G-V-T-A-G-G-P-V-R-A-V-L-E-L-A-G-V-A-D-V-S-S-K-S-L-G-S-N-T-P-I-N-M-V-R-A-T-I-D-G-I-K-Q-L-K-N-A-E-D-V-A-K-L-R-G-K-T-V-E-E-L-L-G


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-S-E-G-S-R-K-E-R-N-R-V-G-R-G-T-G-S-G-N-G-K-T-S-G-R-G-H-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-L-P-L-F-R-R-I-P-K-R-G-F-T-N-I-N-R-K-E-F-A-I-V-N-L-D-V-L-N-R-F-E-D-G-T-E-V-T-P-E-L-L-I-E-T-G-I-I-R-N-E-K-S-G-I-K-I-L-S-D-G-N-I-E-K-K-L-T-V-K-A-N-K-F-S-A-A-A-K-E-A-I-E-A-A-G-G-K-T-E-V-I


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-Y-M-A-K-P-G-E-V-E-R-K-W-Y-V-I-D-A-T-G-V-S-L-G-R-L-S-S-E-V-A-S-I-L-R-G-K-N-K-P-Q-F-T-P-H-I-D-T-G-D-F-V-I-I-I-N-A-G-K-I-G-L-T-G-K-K-A-T-D-K-I-Y-Y-R-H-S-Q-Y-P-G-G-L-K-S-R-T-A-G-E-M-R-T-N-N-P-E-K-L-L-E-L-S-I-K-G-M-L-P-K-N-S-L-G-R-Q-L-F-K-K-L-H-V-Y-G-G-S-E-H-E-H-A-A-Q-K-P-E-V-Y-E-L-R-G


### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-D-L-K-N-L-T-Q-E-E-R-S-E-L-S-L-I-D-V-A-H-F-I-L-E-Q-R-K-E-T-I-L-F-P-E-L-V-K-E-I-Q-A-F-L-G-L-K-D-A-E-I-R-E-R-L-V-Q-F-Y-T-D-M-N-I-D-G-N-F-I-S-L-G-N-N-T-W-G-L-R-A-W-Y-P-M-D-A-I-D-E-E-V-Q-T-Q-T-T-P-K-K-K-R-K-S-D-D-D-D-D-E-D-E-E-I-L-D-D-D-V-D-Y-D-D-E-E-I-V-E-E-L-G-E-E-E-I-S-L-A-D-V-L-L-D-E-D-E-D-D-D-D-H-L-P-D-G-I-E-G-D-L-A-T-V-E-D-D-Y-T-D-G-D-Y-T-E-D-P-E-D-K


### FUNCTION Involved in the decoration of cell wall teichoic acid with galactose and glucose ### SEQUENCE -M-S-R-V-R-Q-L-L-D-K-L-P-W-Y-T-D-N-I-H-S-I-L-M-Y-L-I-M-G-G-F-T-T-L-I-N-I-V-T-F-W-L-C-T-D-V-L-N-W-D-Y-R-I-A-N-T-I-A-W-V-A-S-V-L-F-A-Y-F-S-N-K-K-Y-V-F-E-S-Y-T-P-T-W-K-E-K-A-R-E-V-S-S-F-F-G-F-R-F-L-T-Y-I-V-D-F-L-V-M-I-L-L-I-S-G-L-G-I-N-E-L-W-A-K-I-W-T-N-V-I-V-L-I-L-N-Y-V-F-S-K-W-I-I-F-K-V-R-K


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-L-Q-P-H-L-V-I-G-S-A-F-T-F-G-D-A-F-F-T-L-F-A-F-A-I-L-L-V-L-I-R-I-Y-A-W-K-P-L-M-G-V-M-K-E-R-E-E-H-I-G-S-E-I-D-A-A-E-E-S-R-A-Q-A-E-Q-L-L-A-E-Q-K-S-V-L-Q-Q-A-R-V-E-S-Q-T-M-I-E-N-A-K-Q-L-G-E-K-E-R-E-E-I-V-K-T-A-R-R-E-S-E-R-I-K-E-E-A-K-A-D-I-A-R-E-K-E-D-A-I-S-A-L-R-E-Q-V-G-S-L-S-V-L-I-A-S-K-V-I-E-K-N-L-D-E-K-E-Q-S-N-L-I-Q-D-Y-I-E-R-L-G-D-D-K


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-K-D-L-E-V-A-G-R-Y-A-N-A-L-F-Q-V-A-Q-D-K-D-L-V-D-V-F-S-E-E-L-T-E-L-K-A-A-L-N-A-N-K-D-F-V-K-L-L-E-N-P-T-F-T-T-E-Q-K-K-N-L-A-S-A-V-F-E-K-I-N-P-T-L-R-D-F-I-Y-L-L-I-D-R-S-R-E-D-Y-L-S-V-I-A-D-V-Y-Q-K-R-V-N-D-L-R-G-V-A-D-A-D-V-Y-S-V-V-P-L-S-E-Q-E-L-T-A-L-S-R-V-F-A-A-K-M-N-K-T-K-L-N-I-Q-N-H-I-D-K-S-L-L-G-G-V-K-V-V-I-G-T-R-I-Y-D-D-S-L-K-T-K-L-K-D-M-E-R-Q-I-K-A


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-G-S-L-N-V-S-I-V-T-P-D-G-P-V-Y-E-G-V-A-Q-M-V-I-A-R-T-K-A-G-E-L-G-I-L-P-G-H-V-P-L-V-A-P-L-K-I-D-I-V-R-L-K-V-E-S-G-E-E-W-V-A-V-N-G-G-F-M-E-V-N-G-E-E-V-N-I-L-A-D-T-A-E-R-E-Q-D-I-D-I-D-R-A-E-K-A-K-Q-R-A-E-E-E-L-S-R-A-K-E-Q-K-V-D-E-V-M-A-R-L-A-L-Q-R-A-I-N-R-I-H-A-K-E-H-N


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-N-L-I-P-T-V-I-E-Q-T-S-R-G-E-R-A-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-G-S-A-I-D-D-N-V-A-N-S-I-V-S-Q-L-L-F-L-D-A-Q-D-P-E-K-D-I-F-L-Y-I-N-S-P-G-G-S-I-S-A-G-M-A-I-Y-D-T-M-N-F-V-K-A-D-V-Q-T-I-G-M-G-M-A-A-S-M-G-S-F-L-L-T-A-G-A-N-G-K-R-F-A-L-P-N-A-E-I-M-I-H-Q-P-L-G-G-A-Q-G-Q-A-T-E-I-E-I-A-A-R-H-I-L-K-I-K-E-R-M-N-T-I-M-A-E-K-T-G-Q-P-Y-E-V-I-A-R-D-T-D-R-D-N-F-M-T-A-Q-E-A-K-D-Y-G-L-I-D-D-I-I-V-N-K-S-G-L-K-G


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-L-P-K-D-L-L-Y-T-E-E-H-E-W-V-K-A-E-D-G-S-Y-I-I-G-I-T-D-F-A-Q-D-Q-L-G-D-I-V-F-V-E-L-P-E-V-G-D-T-V-T-K-G-D-S-I-G-S-I-E-S-V-K-T-V-S-D-F-Y-A-P-V-T-G-K-V-V-A-V-N-E-T-L-E-D-E-P-E-L-I-N-S-N-P-Y-D-T-G-W-I-L-K-L-T-E-V-E-E-A-D-V-T-A-L-L-S-S-D-D-Y-E-K-G-L-D


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Y-F-L-Y-V-G-I-F-G-A-L-G-G-M-C-R-Y-A-M-N-L-W-L-G-G-G-D-F-P-S-A-T-L-A-V-N-L-I-G-C-F-L-L-A-F-I-M-P-F-L-A-E-K-S-R-I-S-L-V-L-L-N-G-I-G-T-G-F-I-G-A-F-T-T-F-S-A-F-S-V-D-T-I-E-L-L-Q-Q-G-E-V-V-L-A-I-S-Y-I-L-V-S-L-I-G-G-L-V-M-V-K-F-G-R-R-F-S-N-K-L-L-R-R-G-A-H-H-V-D


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-I-N-F-L-L-V-G-F-G-A-S-L-G-A-M-L-R-Y-G-I-S-I-F-V-K-S-K-W-K-T-D-F-P-Y-A-T-F-F-I-N-I-T-G-S-F-L-L-G-F-L-V-S-T-A-L-G-P-M-W-Q-L-F-L-G-T-G-F-M-G-G-Y-T-T-F-S-T-F-K-V-E-S-M-E-L-K-W-K-A-N-F-Q-V-L-F-S-Y-V-G-L-T-Y-L-C-G-L-I-A-A-F-I-G-I-M-L-G-V


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-I-E-V-L-E-A-E-E-K-T-A-S-G-I-V-L-P-D-S-A-K-E-K-P-Q-S-G-K-I-V-A-V-G-S-G-R-V-L-D-N-G-T-K-E-P-L-E-V-A-E-G-D-T-V-I-F-A-K-Y-S-G-T-E-V-T-Y-E-G-T-D-Y-L-I-L-R-E-S-D-I-L-A-I-S-K


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-K-K-M-L-V-E-F-R-D-F-A-L-K-G-N-V-L-D-L-A-V-A-V-V-I-G-A-A-F-G-K-I-V-S-S-L-V-N-N-I-I-M-P-F-V-G-V-L-L-G-G-L-D-F-S-D-L-S-F-K-V-G-K-S-V-I-Q-Y-G-A-F-I-Q-S-I-V-D-F-V-I-I-A-F-A-I-F-I-F-V-K-V-L-T-S-F-I-K-K-K-E-Q-P-T-E-E-T-P-V-P-P-T-E-E-Y-L-K-E-I-R-D-L-L-K-E-Q-Q-K


### FUNCTION Essential cell division protein ### SEQUENCE -M-S-N-V-A-Y-K-S-N-L-E-P-N-R-V-H-R-E-A-E-Q-P-K-K-Q-I-L-K-R-G-Q-M-T-L-G-E-K-V-I-I-T-I-A-L-A-I-V-L-V-V-A-F-R-I-I-S-V-Q-A-Q-I-Y-T-V-N-Q-E-I-Q-T-K-E-T-K-I-L-E-Q-Q-K-S-N-E-D-L-K-V-E-V-K-D-L-G-R-Y-E-R-I-L-K-I-A-K-E-K-G-L-K-L-D-G-D-N-V-K-V-V-D-G-Q


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-G-L-S-N-K-F-K-S-F-F-F-L-D-E-E-E-E-Y-Y-E-E-E-V-A-R-E-P-E-P-M-Q-K-K-T-K-K-E-K-P-S-K-N-R-F-Y-A-V-E-E-E-D-A-K-V-V-S-M-Q-G-A-Q-F-S-S-R-M-V-L-A-E-P-R-V-Y-A-E-A-Q-E-L-A-D-Y-L-K-D-Y-K-T-V-V-V-N-L-Q-R-I-S-H-D-Q-A-T-R-I-V-D-F-L-S-G-T-V-Y-A-L-G-G-D-I-Q-R-V-G-N-N-I-F-L-C-T-P-D-N-V-E-V-N-G-S-I-S-E-M-L-D-E-Q-N-F-M


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-A-I-K-V-H-I-G-K-T-V-A-L-M-N-D-N-I-D-T-D-Q-I-I-P-K-S-F-L-K-R-I-E-R-T-G-F-G-E-F-L-F-D-S-W-R-Y-L-P-N-R-K-P-N-P-D-F-P-L-N-A-P-D-R-Q-E-A-T-I-L-I-T-G-D-N-F-G-C-G-S-S-R-E-H-A-A-W-A-L-L-D-Y-R-F-R-V-I-I-A-G-S-Y-S-D-I-F-Y-M-N-C-T-K-N-G-V-L-P-I-V-L-P-R-E-A-R-E-K-L-A-K-I-T-A-E-E-K-V-T-I-D-L-P-K-Q-Q-V-I-S-S-V-G-T-Y-P-F-E-I-D-A-T-W-K-N-K-F-I-N-G-L-D-D-I-A-I-T-F-E-H-I-D-A-I-K-A-Y-E-Q-K-V-D-S-I


### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-N-R-E-E-Q-L-G-V-L-E-S-L-L-F-A-A-G-D-A-G-L-S-T-E-Q-L-T-E-V-M-E-I-T-H-I-E-A-L-N-L-L-E-L-L-S-E-R-Y-N-G-N-E-D-R-G-L-I-L-L-E-L-A-G-T-F-Q-L-A-T-K-K-A-H-A-E-F-L-R-K-L-V-E-V-P-S-N-T-V-L-S-Q-A-S-L-E-T-L-A-I-I-A-Y-R-Q-P-V-T-R-M-E-V-D-E-V-R-G-V-Q-T-D-G-P-I-R-T-L-V-A-K-G-L-V-T-D-K-G-R-V-D-G-A-G-R-A-K-L-Y-V-T-T-S-E-F-L-D-A-F-G-L-N-S-L-D-D-L-P-K-L-A-D-P-E-A-E-D-P-D-Q-S-E-M-D-L-F-F-D-R-F-N-Q-S-K-E-Q-E-E-E


### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-H-I-A-L-I-A-H-D-E-K-K-D-L-M-V-G-F-A-T-A-Y-K-H-L-L-E-P-H-Q-L-Y-A-T-G-T-T-G-L-R-I-I-E-A-T-G-L-T-V-H-R-F-K-S-G-P-L-G-G-D-Q-Q-I-G-A-R-I-S-E-N-K-M-D-L-V-I-F-L-R-D-P-L-T-A-Q-P-H-E-P-D-V-S-A-L-I-R-L-C-D-V-Y-E-I-P-L-A-T-N-I-G-T-A-E-I-L-I-R-G-L-G-A-G-F-L-D-W-R-D-L-R-R-N-D-E


### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-T-S-E-Q-F-E-Y-H-L-T-G-K-E-I-L-E-K-E-F-K-T-G-L-R-G-Y-N-P-E-D-V-D-E-F-L-D-M-V-I-K-D-Y-S-T-F-T-Q-E-I-E-A-L-Q-A-E-N-I-R-L-V-Q-E-L-D-N-A-P-V-R-T-T-T-Q-P-A-P-T-F-Q-A-A-A-Q-P-A-G-T-T-N-F-D-I-L-K-R-L-S-N-L-E-K-H-V-F-G-N-K-L-D-D-N-E


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-V-A-K-H-E-H-Q-Q-A-L-V-E-Q-Y-A-E-L-R-R-T-L-K-A-E-G-R-F-D-E-L-R-K-L-P-R-D-S-S-P-T-R-L-H-N-R-C-E-L-T-G-R-P-H-G-Y-M-R-K-F-G-M-S-R-I-R-F-R-E-L-A-H-Q-G-Q-L-P-G-V-K-K-A-S-W


### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-T-K-E-S-L-E-K-A-T-F-A-G-G-C-F-W-C-M-V-K-P-F-D-T-Q-P-G-I-E-K-V-V-S-G-Y-T-G-G-H-T-V-N-P-T-Y-K-E-V-C-S-G-T-T-G-H-T-E-A-V-E-I-T-F-D-P-A-V-F-P-Y-E-K-L-V-E-V-Y-W-Q-Q-T-D-P-T-D-A-A-G-Q-F-V-D-R-G-D-S-Y-R-P-V-I-F-Y-H-N-E-E-Q-R-Q-I-A-E-K-S-K-A-A-L-D-A-S-G-R-F-K-K-P-V-V-T-E-I-A-K-A-E-T-F-Y-P-A-E-E-Y-H-Q-D-F-Y-K-K-E-K-A-H-Y-E-G-Y-Q-V-A-S-G-R-A-A-F-I-D-A-N-W-K-G


### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide  operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-Q-K-Q-V-V-V-M-D-E-A-A-I-K-R-A-L-T-R-V-S-Y-E-I-I-E-R-N-K-G-T-K-N-L-A-L-V-G-I-K-T-R-G-I-Y-L-A-E-R-L-H-K-R-I-L-E-I-E-G-I-D-V-P-V-G-D-I-D-I-T-L-Y-R-D-D-L-S-F-K-D-D-K-T-R-E-P-A-V-H-G-T-N-I-P-F-D-I-N-G-K-K-V-V-L-V-D-D-V-L-Y-T-G-R-T-V-R-A-A-M-D-A-L-M-D-V-G-R-P-A-Q-I-H-L-A-V-L-A-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-G-N-E-R-V-E-V-R-L-T-D-V-D-H-S-E-D-A-V-I-I-N-K-N-E


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-L-Y-P-S-I-D-N-L-L-L-K-I-D-S-K-Y-S-L-V-T-V-A-A-K-R-A-R-Y-M-Q-L-E-N-D-K-G-V-L-P-S-Y-Q-S-D-K-F-V-G-K-A-L-E-E-I-H-A-G-K-L-V-L-Q-N-D-E-K


### FUNCTION Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism ### SEQUENCE -M-K-K-Y-S-K-K-D-R-Q-M-K-L-Q-V-A-I-E-E-N-P-F-I-T-D-E-Q-L-A-E-K-F-G-V-I-V-Q-T-I-R-L-D-R-V-A-L-S-I-P-E-L-R-E-R-I-K-H-V-A-S-V-N-Y-A-D-A-V-K-S-L-P-I-D-E-V-I-G-E-I-I-D-I-Q-L-S-K-S-A-I-S-I-F-D-V-R-S-E-H-V-F-K-R-N-K-I-A-R-G-H-H-L-F-A-Q-A-N-S-L-A-T-A-V-I-P-N-E-L-A-L-T-T-Q-A-T-V-R-F-V-R-S-V-Y-E-G-E-R-I-I-A-K-A-K-V-R-P-A-T-D-N-R-A-I-T-I-V-D-V-K-S-Y-V-G-D-E-I-V-L-K-G-K-F-E-M-Y-H-A-T-Q-K


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-K-M-Y-N-V-G-K-I-V-N-T-H-G-L-I-G-E-I-R-V-I-A-T-T-D-F-P-E-E-R-F-Q-V-G-N-T-V-Y-L-F-E-K-N-S-K-K-P-E-K-L-I-I-R-S-H-R-K-H-K-N-F-D-L-L-M-F-E-G-L-T-G-I-H-Q-V-E-R-M-K-E-G-V-L-K-I-K-E-A-Q-L-T-D-L-E-E-N-E-F-Y-F-H-E-I-I-G-C-T-V-V-T-T-D-G-E-E-L-G-E-I-T-E-I-L-T-P-G-A-N-D-V-W-V-V-K-G-A-D-K-K-E-K-L-I-P-Y-I-A-D-V-V-K-D-I-N-T-N-D-K-K-I-T-I-E-V-M-E-G-L-L-D


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-K-L-I-D-E-I-T-K-S-Q-L-N-P-D-V-P-S-F-R-P-G-D-T-V-R-V-H-A-K-V-V-E-G-T-R-E-R-I-Q-L-F-E-G-V-V-I-K-R-R-G-A-G-I-S-E-T-F-T-V-R-K-I-S-N-G-V-G-V-E-R-T-F-P-V-H-T-P-R-I-A-K-L-E-V-I-R-R-G-K-V-R-R-A-K-L-Y-Y-L-R-N-L-R-G-K-A-A-R-I-K-E-I-R


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-S-N-I-S-K-E-T-V-E-K-V-A-N-L-A-K-L-E-V-S-E-T-E-A-T-A-F-A-G-Q-L-G-K-I-I-E-L-V-E-Q-L-N-T-L-D-T-N-N-V-E-P-T-S-H-A-I-D-V-S-N-V-L-R-E-D-V-A-T-K-G-L-D-R-K-E-V-L-K-N-A-P-D-Q-Q-D-G-M-F-K-V-P-T-I-M-E-Q


### FUNCTION Catalyzes the hydration of fosfomycin ### SEQUENCE -M-I-S-G-L-S-H-I-T-L-I-V-K-D-L-N-K-T-T-T-F-L-E-E-I-F-D-A-E-E-I-Y-S-S-G-D-D-T-F-S-L-S-K-E-K-F-F-L-I-A-G-L-W-I-C-I-M-E-G-E-S-L-Q-E-R-T-Y-N-H-I-A-F-Q-I-Q-A-E-E-M-D-E-Y-I-E-R-I-K-S-L-G-M-E-I-K-P-E-R-S-R-V-K-G-E-G-R-S-V-Y-F-Y-D-Y-D-N-H-L-F-E-L-H-A-G-T-L-E-E-R-L-K-R-Y-H-K


### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-K-K-M-L-I-G-G-I-R-L-Y-Q-K-Y-I-S-R-F-T-P-A-T-C-R-F-Y-P-T-C-S-A-Y-G-I-E-A-I-E-T-H-G-A-L-K-G-S-Y-L-A-I-R-R-I-S-K-C-H-P-F-H-K-G-G-L-D-F-V-P-P-K-K-D-K-N-D-D-S-G-H-T-C-K-A-H-H-H-H


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit ### SEQUENCE -M-A-R-Y-T-G-P-S-W-K-V-S-R-R-L-G-I-S-L-S-G-T-G-K-E-L-E-R-R-P-Y-A-P-G-Q-H-G-P-T-Q-R-K-K-I-S-E-Y-G-L-Q-Q-A-E-K-Q-K-L-R-H-M-Y-G-L-T-E-R-Q-F-K-N-T-F-N-K-A-G-K-L-Q-G-K-H-G-E-N-F-M-I-L-L-E-Q-R-L-D-N-I-V-Y-R-L-G-L-A-R-T-R-R-A-A-R-Q-L-V-N-H-G-H-I-T-V-D-G-K-R-V-D-I-P-S-Y-Q-V-S-V-G-Q-V-I-S-V-R-E-K-S-A-K-N-S-A-I-A-E-S-L-E-V-S-S-F-V-P-E-Y-V-T-F-D-A-E-T-L-T-G-S-L-N-R-L-P-E-R-S-E-L-A-A-E-I-N-E-A-F-I-V-E-F-Y-S-R


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-T-C-K-Y-N-G-T-R-V-V-D-S-R-P-A-D-D-G-N-S-I-R-R-R-R-E-C-E-K-C-G-F-R-F-T-T-F-E-K-V-E-E-S-P-L-I-V-V-K-K-D-G-A-R-E-E-F-A-R-E-K-V-R-R-G-L-I-R-A-C-E-K-R-P-V-S-A-E-Q-I-E-E-I-V-N-E-V-E-R-E-L-R-N-I-G-D-S-E-I-A-S-D-L-I-G-E-K-V-M-N-K-L-A-S-L-D-E-V-A-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-I-S-V-F-V-E-E-L-K-D-L-M-E-K-N-K-D-R


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-D-V-N-N-V-E-L-V-I-S-A-V-R-P-E-Q-Y-P-E-T-D-L-P-E-Y-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-M-I-R-R-K-S-M-A-R-I-S-Q-K-P-G-K-T-Q-T-L-N-F-Y-K-I-E-E-A-L-F-F-V-D-V-P-G-Y-G-F-A-K-V-S-K-T-E-R-E-K-W-G-V-M-I-E-T-Y-I-T-S-R-E-Q-L-R-G-V-I-Q-I-V-D-L-R-H-K-P-T-E-D-D-R-M-M-Y-E-F-L-K-Y-Y-D-I-P-V-I-V-V-A-T-K-A-D-K-I-P-R-S-K-W-Q-K-N-A-K-I-V-R-E-T-L-D-F-D-P-D-D-K-F-V-L-F-S-S-E-T-K-M-G-K-D-E-A-W-Q-F-I-K-E-G-M-E


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-E-T-G-G-K-Q-I-K-V-E-A-G-Q-E-I-Y-V-E-K-L-A-G-E-V-G-D-V-V-T-F-D-K-V-L-F-V-G-G-D-S-A-K-V-G-V-P-F-V-D-G-A-T-V-T-A-K-V-E-K-Q-G-R-A-K-K-L-T-V-Y-K-Y-K-P-K-K-N-Y-H-K-K-Q-G-H-R-Q-P-Y-T-K-L-T-I-D-A-I-N-A


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-M-G-L-D-V-G-S-K-T-V-G-V-A-I-S-D-P-L-G-W-T-A-Q-G-V-E-T-I-Q-I-D-E-S-R-K-Q-F-G-Y-D-R-V-K-E-L-V-L-E-Y-E-V-E-K-V-V-V-G-L-P-K-N-M-N-N-T-I-G-P-R-A-E-S-S-K-I-Y-A-E-V-L-E-S-R-I-G-L-P-V-V-L-W-D-E-R-L-T-T-S-A-A-E-R-T-L-I-E-A-D-V-S-R-K-K-R-K-E-V-I-D-K-L-A-A-V-M-I-L-Q-S-Y-L-D-T-T-N


### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-K-H-K-V-G-I-L-G-G-T-F-D-P-P-H-L-A-H-L-H-M-A-E-E-A-K-A-Q-L-G-L-E-K-I-L-F-L-P-N-K-V-P-P-H-K-Q-I-S-G-M-A-S-N-E-E-R-V-E-M-L-Q-L-M-I-E-D-R-D-S-F-E-I-D-T-R-E-L-M-R-T-G-K-S-Y-T-Y-D-T-M-R-D-M-I-S-E-Q-P-N-T-D-F-Y-F-I-I-G-G-D-M-V-E-Y-L-P-K-W-Y-H-I-D-D-L-V-K-M-V-T-F-V-G-V-N-R-P-L-Y-Q-K-E-V-P-Y-D-I-V-K-I-N-M-P-E-T-A-I-S-S-T-E-I-R-N-D-I-E-H-A-E-A-F-L-P-E-K-V-W-S-Y-I-K-E-H-Q-L-Y-G-K-K


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-E-K-K-N-K-K-E-K-L-A-E-E-I-E-Q-E-E-L-N-S-L-D-E-S-V-E-T-V-E-E-E-A-T-E-E-T-L-T-E-E-Q-A-K-I-L-E-L-E-N-K-L-D-E-V-E-N-R-Y-L-R-M-Q-A-D-F-E-N-V-K-K-R-H-I-A-D-R-D-A-S-Q-K-Y-R-S-Q-S-L-A-Q-D-L-L-P-A-L-D-S-F-E-K-A-L-A-T-T-S-D-Q-E-E-V-K-Q-I-L-K-G-M-E-M-V-Y-N-Q-I-L-V-A-F-E-K-E-G-I-E-V-I-P-A-V-G-E-Q-F-D-P-N-F-H-Q-A-V-M-Q-D-S-D-E-N-A-G-S-N-E-I-T-A-E-L-Q-K-G-Y-K-L-K-D-R-V-I-R-P-S-M-V-K-V-N-Q


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-T-V-L-E-I-D-L-L-D-E-T-N-N-L-P-D-E-D-K-Q-L-V-E-N-I-L-Q-F-A-A-G-Y-L-K-I-E-E-G-T-E-L-S-L-T-F-T-T-N-E-G-I-Q-E-I-N-R-E-Y-R-N-K-D-Q-A-T-D-V-I-S-F-A-L-E-E-M-G-D-G-E-T-E-I-D-W-G-D-F-D-L-E-T-P-R-M-L-G-D-I-I-I-S-T-E-K-A-E-E-Q-A-K-D-Y-G-H-T-K-A-R-E-L-G-F-L-A-V-H-G-L-L-H-L-L-G-Y-D-H-M-E-P-D-E-E-K-V-M-F-G-L-Q-K-E-V-L-D-A-Y-G-L-E-R


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-G-H-R-H-I-I-I-R-E-L-I-T-S-N-E-I-D-T-Q-E-D-L-V-E-L-L-L-E-R-D-V-K-V-T-Q-A-T-V-S-R-D-I-K-E-L-H-L-V-K-V-P-T-Q-T-G-G-Y-K-Y-S-L-P-A-D-N-S-F-N-P-H-Q-K-L-K-R-A-L-I-D-C-F-I-C-I-D-T-V-Q-F-M-I-I-L-K-V-M-P-G-N-G-N-S-V-G-A-L-I-D-N-L-D-W-P-E-K-A-G-T-L-C-G-D-D-T-C-L-I-I-C-R-S-E-E-N-A-K-T-L-T-D-R-F-I-D-M-L


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-T-K-K-K-T-F-E-E-A-I-A-E-L-E-T-I-V-E-A-L-E-N-G-S-A-S-L-E-D-S-L-D-M-Y-Q-K-G-I-E-L-T-K-L-C-Q-D-K-L-Q-S-A-E-Q-R-M-A-K-V-V-T-E-A-G-E-E-I-P-F-E-A-D-G-E


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-K-R-R-E-A-R-E-K-A-L-Q-A-L-F-Q-I-E-L-N-E-M-S-L-D-Q-A-I-K-N-I-M-E-D-E-Q-D-D-Y-M-E-Q-L-V-E-G-V-M-A-N-K-A-E-I-D-A-I-I-E-P-N-L-D-N-W-R-I-D-R-L-N-K-V-D-L-S-L-L-R-L-S-V-Y-E-I-K-Y-L-D-D-V-P-N-R-V-S-L-N-E-S-I-E-I-A-K-I-Y-S-D-E-K-S-S-K-F-I-N-G-V-L-A-N-I-A-P-E-D-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-Q-E-R-K-N-E-I-I-A-E-Y-R-V-H-D-T-D-T-G-S-P-E-V-Q-I-A-V-L-T-A-E-I-N-S-L-N-E-H-V-R-V-H-K-K-D-H-H-S-Y-R-G-L-M-K-M-V-G-H-R-R-N-L-L-T-Y-L-R-K-K-D-V-Q-R-Y-R-E-L-I-K-R-L-G-L-R-R


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-N-V-R-A-N-R-V-S-E-Q-M-K-K-E-L-G-D-I-L-N-R-K-I-K-D-P-R-L-G-F-V-T-V-T-G-V-D-V-T-G-D-L-Q-E-A-K-V-F-I-S-I-L-G-T-D-K-E-K-E-N-T-L-L-A-L-E-K-A-H-G-F-I-R-S-E-I-G-R-R-I-R-L-R-K-V-P-E-M-S-F-E-I-D-N-S-I-A-Y-G-N-R-I-D-E-L-L-R-D-L-N-N-D-Q


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-K-V-L-E-Q-V-E-A-I-V-A-P-I-T-D-E-L-Q-L-E-L-V-D-I-A-F-E-K-E-G-P-N-W-F-L-R-I-F-I-D-K-D-G-G-V-D-I-D-E-C-A-A-V-S-E-K-V-S-E-K-M-D-E-S-D-P-I-T-Q-N-Y-F-L-E-V-S-S-P-G-A-E-R-P-L-K-K-E-Q-D-F-E-N-A-V-G-K-Y-V-H-V-T-S-Y-E-P-I-D-G-R-K-M-W-E-G-T-L-V-S-Y-D-G-T-T-L-V-I-T-I-T-D-K-T-R-K-I-T-C-E-I-P-K-D-K-V-A-K-A-R-L-A-I-Q-F


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-S-K-E-V-L-S-K-S-K-E-K-M-E-K-A-E-Q-A-L-T-R-Q-L-G-T-I-R-A-G-R-A-N-A-S-L-L-D-R-L-T-V-D-Y-Y-G-A-A-T-P-V-N-Q-M-A-S-I-S-V-P-E-A-R-M-L-L-I-T-P-Y-D-K-T-I-L-G-E-I-E-K-A-I-L-K-S-D-L-G-L-T-P-N-N-D-G-S-V-L-R-L-S-I-P-Q-L-T-E-E-R-R-K-E-L-V-K-E-V-K-K-E-A-E-E-A-K-V-A-V-R-N-I-R-R-E-A-N-E-D-L-K-K-L-E-K-N-G-D-I-T-E-D-D-L-R-S-Y-G-E-D-V-Q-K-L-T-D-E-S-I-K-N-I-D-S-I-T-K-D-K-E-A-E-I-L-E-V


### FUNCTION Inhibits cell division during the SOS response Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and/or DivIC to the division machinery ### SEQUENCE -M-T-L-K-L-I-W-D-K-F-Y-V-S-I-I-F-V-I-T-C-L-V-L-G-I-I-L-M-C-T-V-I-G-S-G-S-E-Y-S-E-V-D-V-N-E-G-D-S-I-W-A-L-A-D-Q-Y-A-A-K-S-D-M-A-K-A-D-F-V-S-W-V-E-K-E-N-N-L-T-D-G-H-V-K-A-G-D-Y-V-V-I-P-V-H-E-T-K-L-Q-R-S-D-S-T-I-Q-L-A-N-Q


### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-A-E-K-M-N-V-E-S-F-N-L-D-H-T-K-V-K-A-P-F-V-R-L-A-G-T-K-V-G-V-H-G-D-E-I-Y-K-Y-D-V-R-F-K-Q-P-N-K-E-H-M-E-M-P-A-L-H-S-L-E-H-L-M-A-E-L-A-R-N-H-T-D-K-L-V-D-I-S-P-M-G-C-Q-T-G-F-Y-M-S-F-I-N-H-N-D-Y-D-D-A-L-E-I-L-A-T-T-L-T-D-V-L-A-A-D-S-V-P-A-C-N-E-V-Q-C-G-W-A-A-S-H-S-L-E-G-A-K-E-L-A-E-E-F-L-A-K-R-S-E-W-K-N-V-F-G-E


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-L-T-M-D-D-I-V-R-E-G-H-P-A-L-R-E-V-A-T-E-V-T-F-P-L-S-D-E-E-K-K-L-G-H-D-M-L-E-F-L-I-N-S-Q-D-E-E-L-A-E-K-Y-G-L-R-G-G-V-G-I-A-A-P-Q-L-A-V-T-K-R-F-L-A-I-H-V-H-D-E-K-D-R-L-Y-S-Y-V-L-Y-N-P-K-I-R-S-H-S-V-Q-Q-A-C-L-S-G-G-E-G-C-L-S-V-D-R-E-V-P-G-Y-V-V-R-S-E-R-V-T-I-D-A-F-D-E-N-G-T-P-L-K-L-R-F-K-G-Y-P-A-I-V-V-Q-H-E-I-D-H-L-N-G-V-M-F-Y-D-H-I-N-K-E-N-P-S-Y-L-P-P-D-V-D-V-F-G


### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-F-K-V-F-Y-Q-E-T-L-T-E-T-P-V-R-E-K-T-Q-S-L-Y-V-E-A-E-S-E-V-K-V-R-Q-L-L-K-D-E-P-F-H-I-E-F-V-E-K-I-S-D-A-H-L-A-Y-E-K-E-N-P-D-F-A-L-W-E-K


### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid  by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-A-F-R-E-N-V-L-E-I-L-E-E-I-T-E-T-D-E-V-V-Q-N-T-N-I-K-L-F-D-E-G-L-L-D-S-M-A-T-V-Q-L-L-I-E-I-E-S-R-L-D-I-T-V-P-V-S-E-F-D-R-D-E-W-A-T-P-E-M-I-I-T-Q-L-E-A-L-K


### FUNCTION Negative regulator of sigma-B activity Phosphorylates and inactivates its specific antagonist protein, RsbV Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme ### SEQUENCE -M-A-T-M-H-D-K-I-T-L-Q-L-P-A-K-P-E-Y-V-S-L-G-R-L-S-L-S-G-I-A-S-R-A-G-F-S-Y-E-A-I-E-D-L-K-I-A-V-S-E-A-I-T-N-S-V-K-H-A-F-K-G-E-E-D-G-E-I-T-V-E-Y-H-I-Y-E-D-K-L-E-V-R-V-S-D-N-G-T-S-F-D-L-E-T-R-K-Q-E-I-G-P-Y-E-V-G-E-D-A-E-M-M-R-I-G-G-L-G-L-F-L-I-E-T-L-M-D-D-V-K-L-Y-Y-D-E-G-V-S-V-V-M-T-K-Y-I-N-E-K-Q-V-E-E-N-A-K-S-I-S-T


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-K-G-I-G-L-D-M-I-D-L-D-R-V-K-Q-A-V-E-K-N-P-R-F-I-E-R-I-L-T-E-K-E-T-K-Q-Y-E-K-Y-E-G-S-R-K-I-E-F-L-A-G-R-F-A-A-K-E-A-Y-A-K-A-N-G-T-G-F-G-K-H-L-S-F-T-D-V-E-I-L-Q-V-E-D-G-R-P-H-V-T-M-P-I-K-Q-G-E-T-V-F-V-S-I-T-H-T-A-R-S-A-A-A-Q-V-I-I-E-Q


### FUNCTION Could be involved in the glycerol uptake either via facilitated diffusion or active transport ### SEQUENCE -M-K-F-F-R-G-M-I-G-F-C-I-A-G-M-I-V-M-S-V-W-T-P-L-A-E-N-Y-G-I-F-G-G-Y-L-A-A-F-I-I-I-G-P-M-W-F-M-N-H-H-V-G-L-I-E-N-D-E-D-A-A-F-V-D-M-A-V-G-I-G-I-C-G-I-M-R-D-V-F-M-R-G-G-G-E-L-V-S-S-L-P-T-I-G-L-V-A-I-G-A-V-L-A-G-I-V-A-A-A-I-E-K-D-M-A-R-K-H-E-A-K-Q-E-K-T-E-P-G-M-N-I-K-E-E-E-R-L-N-E-N-Q-L-V


### FUNCTION Could be involved in the glycerol uptake either via facilitated diffusion or active transport ### SEQUENCE -M-S-I-G-I-A-L-A-T-I-A-G-G-F-L-F-P-F-A-I-R-M-M-W-G-K-M-V-D-E-W-G-A-I-G-G-W-M-A-A-A-F-I-V-G-T-V-W-T-I-N-H-G-I-P-K-S-M-I-Y-Q-S-G-T-V-W-V-D-M-A-V-A-A-G-I-G-V-F-T-A-S-L-L-T-G-G-K-F-S-K-S-V-V-N-L-A-A-A-V-V-G-G-V-L-G-G-F-L-L-S-L-F-L


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-N-I-Q-I-V-T-V-G-K-L-K-E-K-Y-L-V-Q-G-I-A-E-Y-L-K-R-L-S-A-Y-A-K-V-S-I-V-E-V-P-D-E-K-A-P-E-V-L-S-D-A-E-M-K-Q-V-K-D-K-E-G-V-R-I-L-A-K-I-P-D-D-A-H-V-I-A-L-A-I-D-G-K-M-K-S-S-E-E-F-A-A-D-L-D-K-L-A-T-Y-G-K-S-K-V-A-F-V-I-G-G-S-L-G-L-S-E-A-V-L-K-R-S-N-E-Q-I-S-F-G-R-L-T-L-P-H-Q-L-M-R-L-V-L-V-E-Q-V-Y-R-A-F-R-I-V-R-G-E-P-Y-H-K


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-N-I-E-E-I-I-A-S-V-K-E-A-S-V-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-V-A-A-A-G-G-G-A-A-E-Q-T-E-F-T-V-E-L-A-S-A-G-D-S-K-I-K-V-I-K-V-V-R-E-I-T-G-L-G-L-K-E-A-K-E-L-V-D-N-A-P-K-A-L-K-E-G-V-A-K-D-E-A-E-E-I-K-A-K-L-E-E-V-G-A-N-V-E-V-K


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-A-G-L-G-N-P-G-K-K-Y-E-R-T-R-H-N-V-G-F-M-V-V-D-E-L-S-F-R-H-Q-T-P-W-K-K-S-K-F-N-G-M-V-S-E-I-N-V-G-G-E-K-M-I-L-V-K-P-L-T-F-M-N-A-S-G-E-C-I-R-P-L-M-D-Y-Y-N-I-Q-I-E-D-V-L-I-V-Y-D-D-L-D-L-P-V-G-K-I-R-L-R-Q-K-G-S-A-G-G-H-N-G-M-K-S-I-I-Q-H-V-K-T-Q-E-F-N-R-I-R-V-G-V-S-R-P-L-K-G-E-V-I-H-Y-V-L-G-D-F-P-K-A-E-Q-P-D-I-I-A-A-I-Q-K-S-A-D-A-I-E-D-F-A-Q-T-P-F-I-E-V-M-N-K-Y-N


### FUNCTION Could be involved in septation ### SEQUENCE -M-Q-V-T-D-V-R-L-R-R-V-E-T-D-G-R-M-R-A-I-A-S-I-T-L-D-E-E-F-V-V-H-D-I-R-V-I-D-G-N-N-G-L-F-V-A-M-P-S-K-R-G-V-D-G-E-F-R-D-I-A-H-P-I-N-S-D-T-R-A-K-I-Q-E-V-V-L-A-E-Y-E-R-V-G-E-E-E-A-T-A-V-T-E-E-E-S-E-S-V-S-A-E


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-K-D-V-K-G-K-G-K-K-G-E-T-K-N-V-A-D-G-Y-A-N-N-F-L-I-K-N-G-Y-A-V-E-A-S-N-A-A-L-S-T-L-S-A-Q-K-K-K-E-D-K-L-A-A-E-E-L-A-E-A-K-A-L-K-E-K-M-E-K-L-T-V-E-L-K-A-K-S-G-E-G-G-R-L-F-G-S-I-T-S-K-Q-I-A-Q-T-L-E-K-T-H-G-I-K-V-D-K-R-K-M-D-L-P-E-A-I-R-A-L-G-H-T-K-V-P-V-K-L-H-H-E-V-T-A-T-L-D-V-H-V-S-E-E


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-M-N-R-V-V-L-V-G-R-L-T-K-D-P-E-L-R-Y-T-P-A-G-V-A-V-A-T-F-T-L-A-V-N-R-T-F-T-N-Q-Q-G-E-R-E-A-D-F-I-N-C-V-V-W-R-K-P-A-E-N-V-A-N-F-L-K-K-G-S-M-A-G-V-D-G-R-V-Q-T-R-N-Y-E-G-N-D-G-K-R-V-Y-V-T-E-I-V-A-E-S-V-Q-F-L-E-P-R-N-S-N-G-G-G-G-N-N-N-Y-Q-G-G-N-N-N-N-N-Y-N-N-G-G-N-N-F-G-Q-A-P-T-N-N-G-G-F-G-Q-D-Q-Q-Q-S-Q-N-Q-N-Y-Q-S-T-N-N-D-P-F-A-S-D-G-K-P-I-D-I-S-D-D-D-L-P-F


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-R-K-Y-E-I-M-Y-I-I-R-P-N-I-E-E-D-E-K-K-A-V-V-E-R-F-D-G-I-L-T-E-N-G-A-E-I-I-E-S-K-E-W-G-K-R-R-L-A-Y-E-I-N-D-Y-R-D-G-F-Y-H-I-V-K-L-N-A-D-K-A-D-S-I-N-E-F-D-R-L-A-K-I-S-D-D-I-V-R-H-M-V-I-K-E-E-A


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-V-N-F-N-Q-F-L-K-Q-A-Q-S-M-Q-K-K-M-Q-E-A-Q-E-Q-M-A-N-A-R-Y-T-G-K-A-G-G-G-L-V-E-V-I-A-T-G-K-G-E-V-E-K-I-S-I-D-E-S-L-L-K-A-E-E-K-E-M-L-E-D-L-I-K-V-A-F-N-D-A-Q-Q-K-C-D-E-D-S-Q-N-S-L-S-G-A-L-N-G-M-R-L-P-P-G-F-K-M-P-F


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-N-T-K-F-P-I-T-A-K-G-F-E-K-L-E-H-E-L-K-H-L-K-H-V-E-R-K-K-I-S-A-D-I-A-E-A-R-E-H-G-D-L-S-E-N-A-E-Y-E-A-A-R-E-K-Q-A-F-I-E-G-R-I-K-E-L-E-D-M-T-A-R-A-E-I-I-D-I-G-K-L-S-G-D-N-I-K-F-G-A-T-V-T-L-I-D-D-D-T-E-E-E-V-T-Y-I-I-V-G-E-Y-E-A-D-I-T-R-K-R-V-S-I-A-S-P-I-A-K-A-L-I-G-K-S-V-G-D-F-V-E-V-T-T-P-K-G-S-K-S-Y-E-V-V-T-V-E-Y-K-E-L-E-L


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-G-S-L-N-K-V-I-L-I-G-N-V-G-R-D-P-E-M-R-T-T-G-E-G-K-K-I-I-N-L-S-L-A-T-T-E-T-W-K-D-R-I-T-S-E-R-K-E-R-T-E-W-H-R-V-V-I-F-S-E-G-L-V-S-V-V-E-R-Y-V-T-K-G-S-K-L-Y-I-E-G-S-L-Q-T-R-K-W-N-D-N-S-G-Q-E-K-Y-T-T-E-V-V-L-Q-N-F-N-S-Q-L-I-L-L-D-S-K-N-S-N-N-H-N-Q-D-S-G-H-S-E-Y-K-H-P-E-T-K-N-H-S-F-D-H-S-D-L-D-D-E-I-P-F


### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-T-Y-V-V-T-D-E-C-V-K-C-K-Y-T-D-C-V-E-V-C-P-V-D-C-F-Y-E-G-E-R-E-D-D-F-M-L-V-I-N-P-D-E-C-I-D-C-G-V-C-V-P-D-C-P-I-G-A-I-K-P-E-S-P-G-L-I-E-W-V-E-R-A-K-D-F-I-E-N-K-G-W-K-N-I-T-K-K-K-T-A-L-P-D-A-D-K-F-K-D-E-K-D-K-F-N-K-Y-I-G-S-V-K-I-A-N


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-S-K-D-D-L-I-Q-F-T-G-T-V-L-E-L-L-P-N-A-T-F-R-V-K-L-E-N-D-H-V-I-I-A-H-T-S-G-R-M-R-K-N-R-I-R-I-L-L-G-D-K-V-M-V-E-M-T-P-Y-D-L-T-K-G-R-V-I-H-R-H


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-K-G-N-L-I-K-N-Y-A-V-A-L-L-N-N-A-M-V-D-N-I-Q-D-K-I-F-E-E-I-T-S-I-N-R-I-I-T-D-N-F-D-I-R-E-F-L-F-S-P-I-V-N-K-N-D-K-I-N-A-V-N-S-L-A-K-N-I-K-I-S-T-I-V-Q-N-F-L-L-L-L-V-K-N-S-R-T-A-I-L-S-N-I-V-D-A-Y-N-T-L-L-Y-E-S-K-N-I-K-I-V-Q-V-I-S-A-N-K-L-Q-P-K-E-Q-E-W-I-K-S-R-I-E-K-E-L-N-Q-T-T-E-I-L-F-D-I-D-N-T-I-I-G-G-I-I-I-K-Y-D-S-M-L-Q-D-Y-S-I-K-G-S-L-E-K-I-K-K-A-L-K-I-V-N-I-A-V


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-N-A-T-I-L-V-K-I-I-T-P-L-S-I-A-L-E-K-Q-A-K-M-V-T-M-S-G-E-E-G-M-F-G-V-L-P-S-H-V-P-M-I-V-S-L-K-A-G-L-V-Q-V-Y-I-D-D-M-H-K-S-E-N-T-Y-L-I-S-G-G-V-T-E-V-T-A-N-Y-I-N-I-A-T-E-T-A-I-N-V-T-N-L-S-E-V-E-I-A-T-K-L-L-D-L-Q-K-T-L-S-D-Q-H


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-E-F-K-I-M-S-T-T-D-K-I-E-Q-K-V-I-E-M-V-A-E-K-L-N-K-D-K-S-I-I-T-T-D-S-R-F-I-E-D-L-K-A-D-S-L-D-T-V-E-L-M-M-A-I-E-V-E-Y-G-I-D-I-P-D-D-E-A-T-K-I-K-T-V-S-D-V-I-K-Y-I-K-E-R-Q-S


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-F-A-V-I-K-A-G-G-K-Q-Y-K-V-D-R-N-S-I-I-K-V-E-K-I-D-G-E-L-G-S-K-I-Q-F-D-Q-I-L-M-I-G-E-Y-S-K-P-S-F-I-G-T-P-I-V-K-G-A-V-V-T-A-E-I-T-N-Q-L-K-D-N-K-I-I-V-F-K-K-K-R-R-K-N-Y-R-R-K-A-G-H-R-Q-E-L-T-E-L-K-I-L-D-I-T-K-Q


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-M-S-L-S-H-L-L-I-V-L-L-I-I-F-V-L-F-G-A-G-K-L-P-Q-V-M-S-D-L-A-K-G-L-K-A-F-K-D-G-M-K-D-D-G-S-D-N-D-K-N-K


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-N-V-E-I-V-R-N-Y-N-K-W-R-E-H-K-Q-I-N-K-S-L-I-K-K-I-T-Q-N-I-L-L-R-F-D-N-F-S-K-I-K-Q-F-E-L-S-I-L-L-T-N-A-A-E-I-L-T-L-N-K-Q-F-R-N-I-E-K-A-T-N-V-L-S-F-P-S-N-E-L-N-W-Q-D-L-Y-S-K-L-E-F-L-G-D-S-D-Y-M-H-L-G-D-I-A-F-C-Y-E-V-I-Y-N-E-S-C-E-Q-H-K-T-F-E-N-H-F-I-H-L-L-I-H-S-I-L-H-L-I-G-F-D-H-Q-N-D-T-E-A-N-I-M-E-N-L-E-I-E-I-L-S-Y-F-G-I-F-P-P-Y


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-K-N-K-I-K-I-R-L-K-S-F-D-H-R-S-L-D-Q-A-T-K-E-I-V-S-A-V-K-R-T-F-A-N-I-N-G-P-I-P-L-P-K-K-I-G-R-F-T-V-N-R-S-P-H-V-H-K-K-S-R-E-Q-F-E-I-R-K-H-K-R-L-L-V-I-G-D-P-N-P-A-V-V-D-A-L-S-K-V-D-L-A-A-G-V-D-V-V-I-E-L-E-S-G-E


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-S-S-Y-K-Y-Y-D-L-I-R-K-P-I-I-T-E-K-T-T-T-L-S-E-Q-N-K-Y-A-F-Y-V-D-K-F-A-K-K-L-T-L-K-K-A-I-E-E-I-F-K-V-K-V-K-K-V-N-I-L-N-V-K-G-K-K-K-R-F-K-G-I-I-G-T-Q-I-N-R-K-K-A-I-V-T-L-E-K-D-H-N-I-D-F-A-G-G-I-K


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-I-W-K-G-P-F-V-D-G-Y-L-I-K-K-V-Q-K-L-M-E-S-G-K-S-E-M-I-K-T-W-S-R-R-S-T-I-L-P-I-F-V-G-F-T-F-S-V-H-N-G-N-K-F-I-P-V-S-V-N-E-E-M-V-G-R-K-L-G-E-F-A-P-T-R-T-F-H-G-H-G-A-D-K-K-I-K-R-K


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-V-Q-E-N-K-N-F-A-T-A-Q-A-K-S-I-R-V-S-S-R-K-L-N-L-V-A-A-F-I-R-N-M-K-V-S-E-A-L-V-Q-L-T-F-S-P-K-R-I-A-K-V-V-K-D-C-L-Q-S-A-V-A-N-A-E-N-N-L-G-L-D-I-D-R-L-V-V-T-K-A-T-V-G-K-A-L-V-M-K-R-V-M-P-R-A-K-G-R-A-T-R-I-N-K-F-F-S-N-L-Y-I-T-V-T-E-K-E-D-N


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-A-P-K-K-Q-K-F-R-K-A-H-K-G-R-V-A-S-T-A-K-A-G-T-T-L-A-F-G-S-F-G-L-K-S-I-D-G-W-R-V-T-A-R-Q-I-E-A-G-R-K-A-A-T-R-C-M-K-R-Q-G-R-L-W-I-R-I-F-P-D-V-P-V-S-K-K-P-A-E-V-R-M-G-K-G-K-G-S-P-E-F-F-A-V-R-V-S-P-G-R-I-M-F-E-I-E-G-V-E-E-N-V-A-L-R-A-L-E-L-A-S-A-K-L-P-V-R-T-R-I-V-R-R-Y-E


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-P-K-R-V-L-Q-G-V-V-I-S-S-K-A-D-K-T-V-T-V-K-V-E-R-K-F-K-H-P-I-Y-K-K-F-V-K-V-S-K-K-Y-A-A-H-D-S-E-N-K-Y-Q-E-G-D-K-V-S-I-I-E-S-R-P-I-S-K-T-K-T-W-V-V-V-N-G-E


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-I-L-E-V-A-D-N-S-G-A-K-K-V-M-C-I-K-V-L-G-G-S-H-H-M-V-A-K-L-G-D-V-I-V-V-S-V-K-D-A-I-P-G-G-K-V-K-K-G-D-V-Y-K-G-V-I-V-R-T-K-T-G-V-V-R-P-D-G-S-T-I-K-F-D-Q-N-A-L-V-L-L-N-K-Q-D-E-P-I-G-T-R-V-F-G-P-V-T-R-E-L-R-A-K-K-Y-V-R-I-M-S-L-A-E-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-I-K-L-K-V-K-K-G-D-E-V-V-V-I-T-G-K-H-K-G-K-K-G-K-I-L-K-V-F-P-E-D-S-K-V-I-V-S-G-V-N-V-V-K-K-H-T-K-S-N-Q-M-S-E-G-G-I-I-T-K-E-L-P-I-H-I-S-N-I-A-H-I-D-P-K-T-G-N-P-T-K-V-A-F-K-F-L-E-D-G-S-K-V-R-V-A-K-K-S-G-E-I-I-G-K-E-G-K


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-L-R-F-K-E-L-Y-Q-Q-K-I-I-E-N-L-Q-K-K-F-S-Y-K-N-K-H-E-I-P-Q-I-K-K-I-V-I-N-M-G-V-G-E-A-T-A-D-S-K-V-I-N-N-A-V-N-D-L-T-L-I-S-G-Q-K-P-V-V-T-L-A-R-K-S-I-A-T-F-K-L-R-E-N-M-K-I-G-C-K-V-T-L-R-K-D-R-M-Y-D-F-L-E-R-L-V-I-V-A-L-P-R-V-K-E-F-R-G-F-S-Y-K-S-F-D-G-K-G-N-F-T-F-G-L-K-E-Q-I-V-F-P-E-I-N-Y-D-K-I-D-T-I-R-G-M-D-I-T-I-V-T-S-A-K-T-D-Q-E-S-K-F-L-L-S-G-F-N-L-P-F-Y-N


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-V-S-S-I-K-K-N-E-S-R-K-K-K-S-Q-S-L-H-N-K-R-L-A-L-K-S-K-I-Y-D-K-N-I-S-L-E-E-R-F-S-L-V-M-S-L-A-Q-L-P-R-N-S-S-S-T-R-I-R-N-R-C-E-L-T-G-R-P-R-G-V-T-R-K-F-G-I-S-R-N-K-L-R-E-L-I-G-R-G-L-V-P-G-V-V-K-S-S-W


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-T-D-N-V-A-D-M-L-T-R-I-R-N-A-Y-K-S-K-L-I-N-V-S-F-P-S-S-K-I-K-T-S-I-L-D-V-L-Q-K-E-G-Y-I-K-D-Y-I-T-T-Q-K-N-N-I-S-Y-T-E-V-A-L-K-Y-S-V-N-G-D-A-S-I-C-E-I-H-R-V-S-K-P-G-K-R-V-Y-S-A-I-K-D-L-K-G-Y-Y-N-N-M-G-I-Y-I-L-S-T-P-Y-G-V-M-S-D-R-E-A-H-I-K-N-V-G-G-E-V-I-C-K-V-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-G-K-L-P-I-T-I-P-E-G-V-K-I-G-L-N-D-L-E-V-K-I-S-G-P-K-G-E-L-S-K-T-F-K-G-N-I-A-I-S-L-A-E-N-K-L-L-V-K-P-L-A-A-N-K-N-A-R-A-M-W-G-T-A-R-S-I-I-S-N-M-V-T-G-V-K-E-G-F-K-L-K-L-E-I-N-G-V-G-Y-R-A-M-V-K-G-K-Y-L-N-L-M-L-A-K-S-H-N-T-K-I-E-I-P-S-D-I-K-I-E-M-P-K-Q-N-I-I-I-L-E-G-T-D-K-E-K-L-G-Q-F-A-S-I-I-I-K-Q-R-P-P-E-P-Y-K-G-K-G-I-K-F-E-N-Q-C-I-P-R-K-E-G-K-K-N


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-R-S-A-K-L-K-F-E-K-R-R-S-R-I-R-H-K-I-S-K-T-S-N-R-V-R-L-S-I-F-K-S-G-R-H-I-Y-A-Q-I-I-D-D-S-K-S-I-T-I-A-A-A-S-T-L-D-E-K-I-K-K-L-K-K-S-H-C-N-I-E-N-A-I-K-V-G-E-E-I-A-K-K-A-D-S-A-G-I-K-D-V-V-F-D-R-G-G-Y-K-Y-H-G-V-V-K-A-L-A-D-A-A-R-E-K-I-K-F


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-S-K-V-K-K-N-D-E-T-L-S-E-V-L-V-D-V-N-R-V-T-K-V-V-K-G-G-R-S-F-A-F-S-A-Y-V-V-V-G-D-K-A-G-R-V-G-A-G-H-G-K-A-K-E-V-N-E-A-R-G-K-A-K-Q-A-A-K-K-R-M-M-K-V-P-L-Y-Q-N-R-T-I-H-H-D-V-V-G-K-S-G-A-A-K-V-I-L-R-R-A-K-A-G-T-G-I-I-A-G-G-S-M-R-A-I-F-D-S-L-G-V-H-D-I-V-A-K-S-I-G-S-T-N-V-Y-A-M-I-S-A-T-F-D-A-L-N-K-L-A-S-P-K-S-I-A-M-R-R-D-K-K-V-N-E-I-S-V-K-S-A-E-I-Q-V-N-E


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-E-L-Y-N-N-I-G-A-K-K-N-K-K-R-I-A-R-G-I-G-S-G-K-G-K-T-G-G-R-G-I-K-G-Q-K-S-R-S-G-V-A-I-K-G-F-E-G-G-Q-T-P-I-I-K-R-L-P-K-R-G-F-N-C-I-S-T-K-K-Y-N-I-I-N-I-Y-N-I-E-E-A-L-A-D-G-R-L-S-A-D-D-N-I-T-K-E-K-L-V-E-A-R-V-V-N-N-K-N-N-K-K-L-V-K-L-L-S-I-C-S-D-D-F-A-A-P-L-S-L-K-L-D-A-Y-S-S-K-A-K-D-L-I-E-K-A-G-G-K-L-L


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-S-V-N-I-P-D-N-K-R-L-V-V-S-L-T-Y-I-Y-G-L-G-P-A-M-A-A-E-I-C-N-K-A-K-I-S-K-D-K-K-V-K-E-L-T-D-Q-E-L-I-G-L-R-N-I-I-E-S-E-Y-K-V-E-G-D-L-R-R-E-V-T-L-N-I-K-K-K-K-D-I-R-C-Y-Q-G-L-R-H-I-R-K-L-P-V-R-G-Q-N-T-H-S-N-A-R-T-R-K-G-K-A-I-A-I-A-G-K-K-K-A-V-K


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-N-Q-T-V-K-V-K-K-K-K-K-T-I-T-L-G-V-V-H-I-R-A-S-F-N-N-T-I-V-T-F-T-D-I-Q-G-N-T-I-A-S-A-S-A-G-G-N-G-F-K-G-A-R-K-A-T-P-Y-A-A-Q-V-T-I-D-R-A-S-E-K-A-K-E-Y-G-L-K-T-I-S-I-R-I-G-G-P-G-A-Q-R-E-S-A-M-R-A-L-F-G-Q-N-F-V-V-T-S-I-L-D-V-S-S-I-A-H-N-G-V-R-P-P-K-R-R-R-V


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-H-S-S-A-K-K-A-A-R-Q-T-V-K-R-T-L-I-N-K-K-R-S-S-A-I-K-T-F-I-K-K-V-V-H-E-I-S-I-G-N-K-E-N-A-N-I-A-L-S-V-A-Q-S-K-I-M-Q-G-V-K-K-N-I-I-K-L-N-T-A-S-R-K-I-S-R-L-S-R-Q-I-K-S-L-K-V-N-N-T-L


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-I-D-D-N-I-E-N-N-E-Q-T-I-N-D-I-A-E-E-I-V-E-T-A-N-P-E-V-T-A-L-K-A-E-I-E-E-L-K-D-K-L-I-R-T-T-A-E-I-D-N-T-R-K-R-L-E-K-A-R-D-E-A-K-D-Y-A-I-A-T-F-A-K-E-L-L-N-V-S-D-N-L-S-R-A-L-A-H-K-P-A-N-S-D-V-E-V-T-N-I-I-A-G-V-Q-M-T-K-D-E-L-D-K-V-F-H-K-H-H-I-E-E-I-K-P-E-I-G-S-M-F-D-Y-N-L-H-N-A-I-A-Q-I-E-H-P-D-H-A-P-N-S-I-I-T-L-M-Q-S-G-Y-K-I-R-D-R-L-L-R-P-A-T-V-Q-V-V-K-K-P