### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-R-D-I-L-K-M-G-D-E-R-L-L-R-I-A-P-P-V-P-E-H-M-L-G-S-A-E-L-Q-Q-L-I-D-D-M-F-E-T-M-R-H-V-G-G-V-G-L-A-A-P-Q-V-G-I-D-L-Q-L-V-I-F-G-F-E-R-S-E-R-Y-P-D-A-E-A-V-P-Q-T-I-L-L-N-P-V-I-T-P-T-S-S-E-V-E-D-G-W-E-G-C-L-S-V-P-G-L-R-G-V-V-P-R-F-K-H-I-C-Y-Q-G-I-D-P-Q-G-S-P-I-N-R-F-A-D-G-F-H-A-R-V-V-Q-H-E-C-D-H-L-I-G-R-L-Y-P-S-R-I-Q-D-F-A-K-F-G-Y-T-E-V-L-F-P-G-L-E-V-S-E-D


### FUNCTION Involved in tetrahydrobiopterin biosynthesis Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 May also have a positive regulatory role in the expression of phhA ### SEQUENCE -M-N-A-L-N-Q-A-H-C-E-A-C-R-A-D-A-P-K-V-T-D-E-E-L-A-E-L-I-R-E-I-P-D-W-N-I-E-V-R-D-G-H-M-E-L-E-R-V-F-L-F-K-N-F-K-H-A-L-A-F-T-N-A-V-G-E-I-A-E-A-E-G-H-H-P-G-L-L-T-E-W-G-K-V-T-V-T-W-W-S-H-S-I-K-G-L-H-R-N-D-F-I-M-C-A-R-T-D-K-V-A-E-T-A-E-G-R-K


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-K-G-G-M-A-G-L-M-K-Q-A-Q-Q-M-Q-E-K-M-Q-K-M-Q-E-E-L-A-N-A-E-V-T-G-Q-S-G-G-G-L-V-S-V-V-M-T-G-R-H-D-V-K-R-V-S-I-D-Q-S-L-M-S-T-D-E-D-D-K-E-V-L-E-D-L-I-A-A-A-L-N-D-A-V-R-K-V-E-Q-S-S-Q-E-K-M-G-G-M-T-A-G-M-Q-L-P-P-G-F-K-M-P-F


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-S-F-S-P-L-I-R-Q-L-I-D-G-L-R-I-L-P-G-V-G-Q-K-T-A-Q-R-M-A-L-Q-L-L-E-R-D-R-S-G-G-L-R-L-A-Q-A-L-T-Q-A-M-E-G-V-G-H-C-R-Q-C-R-T-L-T-E-Q-E-L-C-P-Q-C-A-D-P-R-R-D-D-T-Q-L-C-V-V-E-G-P-T-D-V-Y-A-V-E-Q-T-G-Y-R-G-R-Y-F-V-L-K-G-H-L-S-P-L-D-G-L-G-P-E-A-I-G-I-P-Q-L-M-A-R-I-E-E-Q-G-T-F-T-E-V-I-L-A-T-N-P-T-V-E-G-E-A-T-A-H-Y-I-A-Q-L-L-S-E-K-G-L-V-A-S-R-I-A-H-G-V-P-L-G-G-E-L-E-M-V-D-G-G-T-L-A-H-A-F-A-G-R-R-P-I-S-L


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-H-S-D-A-F-D-L-K-A-L-I-R-P-V-V-D-F-P-K-P-G-V-I-F-R-D-I-T-P-L-F-Q-S-P-R-G-L-R-Y-V-A-D-Q-F-I-E-R-Y-V-E-A-E-F-S-H-I-G-A-M-D-A-R-G-F-L-I-G-S-I-I-A-H-Q-L-N-K-P-L-I-L-F-R-K-Q-G-K-L-P-A-D-V-L-S-E-G-Y-Q-T-E-Y-G-E-A-F-L-E-V-H-A-D-S-L-C-E-G-D-S-V-L-I-F-D-D-L-I-A-T-G-G-T-L-L-A-A-A-N-L-V-R-R-T-G-A-Q-V-F-E-A-A-A-I-I-D-L-P-E-L-D-G-S-R-R-L-Q-A-A-G-V-P-T-F-C-L-T-E-F-S-L-S-E-Y


### FUNCTION Part of the high-affinity ATP-driven potassium transport  system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-T-A-Y-L-R-P-A-L-S-L-A-L-L-M-T-L-V-T-G-A-L-Y-P-L-A-V-T-G-I-A-Q-V-A-F-P-N-Q-A-N-G-S-L-V-R-D-A-Q-G-Q-V-R-G-S-A-L-I-A-Q-D-F-Q-G-D-G-W-F-H-S-R-P-S-A-G-A-Y-A-T-V-A-S-G-A-S-N-L-S-P-S-N-P-A-L-A-E-R-V-K-G-D-A-A-T-L-Y-Q-A-Q-Q-G-P-V-P-Q-A-L-L-T-T-S-G-S-G-L-D-P-H-L-P-P-E-A-L-A-Y-Q-I-P-R-V-A-A-A-R-Q-L-P-V-E-R-L-Q-A-L-L-E-Q-A-T-L-H-P-L-I-G-P-P-V-V-N-V-L-A-L-N-Q-A-L-E-K-L-A-I-V-R


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-H-A-P-S-E-I-R-L-T-F-N-Q-D-R-P-Q-S-N-E-D-D-G-S-G-L-A-V-Q-E-A-K-P-I-L-Q-A-P-P-M-Y-K-V-V-L-F-N-D-D-Y-T-P-M-D-F-V-V-E-V-L-E-T-F-F-S-L-N-R-E-L-A-T-K-I-M-L-T-V-H-T-E-G-R-A-V-C-G-L-F-T-R-D-I-A-E-T-K-A-M-Q-V-N-Q-Y-A-R-E-S-Q-H-P-L-L-C-E-I-E-K-D-G


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-A-L-I-A-A-V-S-A-G-G-I-A-G-T-L-L-R-F-A-T-T-N-W-V-A-A-H-W-P-R-H-F-Y-A-G-T-L-A-V-N-L-V-G-C-L-L-I-G-L-L-Y-G-L-F-L-H-K-P-L-A-P-V-E-L-R-A-G-L-I-V-G-F-L-G-G-L-T-T-F-S-S-F-S-L-D-T-V-R-L-M-E-S-G-Q-V-P-L-A-L-G-Y-T-S-I-S-V-V-G-G-L-L-A-T-W-A-G-L-S-L-T-R-F


### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-K-V-G-E-S-I-V-I-N-D-D-I-K-V-T-I-L-G-V-K-G-M-Q-V-R-I-G-I-D-A-P-K-D-V-Q-V-H-R-E-E-I-F-K-R-I-Q-A-G-S-P-A-P-E-K-H-E-D-T-H


### FUNCTION Transcriptional regulator ### SEQUENCE -M-Q-R-I-T-I-T-L-D-E-E-L-L-D-V-I-D-R-R-V-A-T-Q-G-Y-Q-G-R-S-E-A-I-R-D-L-L-R-A-G-M-R-E-S-E-A-L-P-D-D-A-A-C-V-A-V-V-S-Y-L-Y-D-H-S-T-R-E-L-P-R-R-L-N-Q-T-L-H-A-H-H-D-L-T-R-S-T-L-H-V-H-L-D-A-G-H-C-L-E-V-S-V-L-Q-G-E-S-G-R-I-G-E-L-S-R-Q-L-M-V-E-R-G-V-E-H-G-Q-V-Q-V-I-P-A-P-G-Q-P-K-V-R


### FUNCTION General inhibitor of family S1 serine proteases ### SEQUENCE -M-R-P-T-P-M-T-A-I-L-A-L-S-L-A-A-A-A-P-A-M-A-A-S-L-K-D-I-A-P-Y-P-E-A-E-K-G-F-T-R-Q-V-I-H-L-P-A-Q-A-D-E-S-A-Y-K-L-E-I-L-A-G-K-T-L-Q-V-D-C-N-R-Q-R-L-G-G-N-L-E-A-H-T-L-E-G-W-G-Y-N-Y-Y-R-L-D-N-V-S-G-P-A-S-T-L-M-A-C-P-D-G-K-K-T-E-A-F-V-P-V-V-G-D-G-F-L-L-R-Y-N-S-K-L-P-V-V-V-Y-V-P-K-D-V-E-V-R-Y-R-V-W-S-A-S-Q-D-V-Q-K-A-K-V-E


### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-I-V-L-S-R-R-I-S-E-P-G-T-R-V-V-S-G-T-V-T-L-D-V-D-S-R-I-K-S-R-L-R-V-T-L-D-D-G-R-E-A-G-L-M-L-E-R-G-H-L-L-R-G-G-E-L-L-A-D-A-E-G-T-Q-L-I-R-V-L-A-A-P-E-A-V-S-T-V-R-C-A-D-P-H-L-L-A-R-A-A-Y-H-L-G-N-R-H-V-P-L-Q-I-E-P-G-L-L-R-F-Q-H-D-H-V-L-D-D-M-L-R-G-L-G-L-T-V-E-A-E-Q-A-P-F-E-P-E-A-G-A-Y-Q-S-A-P-H-G-H-S-H-S-H-A-H-G-H-D-H-P-F-V-R-L-P-A-H-S


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-K-R-H-K-K-I-L-K-L-A-K-G-Y-Y-G-A-R-S-R-V-F-R-V-A-K-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-K-K-R-Q-F-R-A-L-W-I-A-R-I-N-A-G-A-R-T-N-G-L-S-Y-S-R-L-I-A-G-L-K-K-A-S-I-E-I-D-R-K-V-L-A-D-L-A-V-N-E-K-A-A-F-A-A-I-V-E-K-A-K-A-V-L-A


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-T-I-K-R-E-M-R-N-D-K-R-A-V-P-K-A-P-I-N-E-N-I-S-A-R-E-V-R-L-I-G-A-D-G-E-Q-V-G-I-V-S-I-D-E-A-L-R-I-A-D-E-A-K-L-D-L-V-E-I-S-A-D-A-V-P-P-V-C-K-V-M-D-Y-G-K-H-L-F-E-K-K-K-Q-A-N-E-A-K-K-N-Q-K-Q-I-Q-I-K-E-I-K-F-R-P-G-T-E-D-G-D-Y-Q-V-K-L-R-N-L-V-R-F-L-T-D-G-D-K-A-K-I-S-L-R-F-R-G-R-E-M-A-H-Q-E-L-G-M-E-L-L-K-R-V-E-A-D-L-A-E-Y-G-T-V-E-Q-H-P-K-M-E-G-R-Q-L-M-M-V-I-A-P-K-K-K-K


### FUNCTION Toxic component of a type II toxin-antitoxin  system Expression in Ecoli inhibits cell growth In vivo it is probably neutralized by cognate antitoxin Xre ### SEQUENCE -M-I-L-W-R-I-S-A-Y-A-D-L-S-G-T-G-G-L-R-V-S-G-R-W-H-Q-A-G-R-P-V-V-Y-A-A-T-S-P-P-G-A-M-L-E-V-L-V-H-L-E-I-D-P-E-D-F-P-T-T-M-R-L-L-R-I-E-L-P-D-T-V-S-Q-A-Q-L-P-A-L-Q-P-G-W-S-A-Q-P-E-L-T-R-T-L-G-N-R-F-L-D-D-C-S-A-L-L-L-P-V-P-S-A-I-M-P-S-T-T-N-Y-L-F-N-P-R-H-P-Q-A-Q-S-A-K-I-Q-V-E-D-F-T-P-D-S-R-L-F


### FUNCTION Probable antitoxin component of a type II toxin-antitoxin  system In vivo probably neutralizes the toxic effect of cognate toxin Res ### SEQUENCE -M-S-A-N-A-E-K-E-H-A-M-L-A-E-V-L-R-D-N-G-Y-H-E-Y-R-A-R-L-Q-A-L-L-D-I-P-E-L-A-S-D-F-E-I-H-T-R-I-T-D-G-F-A-A-T-W-L-V-K-L-T-E-R-G-V-L-T-P-V-E-R-D-Q-I-I-P-L-R-T-L-K-S-R-I-E-R-D-Q-P-L-T-V-D-E-S-D-R-L-F-R-S-A-H-I-T-A-M-A-E-A-V-F-G-E-A-G-K-A-K-R-W-L-S-K-P-K-E-R-F-S-G-L-T-P-M-Q-M-L-T-T-Q-Q-G-T-T-Q-V-E-E-M-L-L-Q-I-A-E-G-Y-G-L


### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-S-A-I-T-I-T-D-A-A-H-D-Y-L-A-D-L-L-S-K-Q-N-T-P-G-I-G-I-R-I-F-I-T-Q-P-G-T-Q-Y-A-E-T-C-I-A-Y-C-K-P-G-E-E-K-P-D-D-T-A-V-G-L-K-S-F-T-A-Y-L-D-A-V-S-V-P-F-L-E-D-A-L-V-D-Y-A-T-D-R-M-G-G-Q-L-T-I-K-A-P-N-A-K-V-P-M-V-N-E-D-S-P-I-N-E-R-I-N-Y-Y-L-Q-T-E-I-N-P-G-L-A-S-H-G-G-Q-V-S-L-V-D-V-V-D-D-G-I-A-V-L-Q-F-G-G-G-C-Q-G-C-G-Q-A-D-V-T-L-K-E-G-I-E-R-T-L-L-E-R-I-P-E-L-K-G-V-R-D-V-T-D-H-S-Q-K-E-N-A-Y-Y


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreB releases sequences of up to 9 nucleotides in length ### SEQUENCE -M-S-T-N-I-I-T-T-E-G-H-E-A-L-K-K-E-L-D-H-L-W-R-V-Y-R-P-E-I-T-Q-K-V-A-W-A-A-S-L-G-D-R-S-E-N-A-D-Y-Q-Y-N-K-K-L-L-R-E-I-D-R-R-V-R-Y-L-R-K-R-L-E-D-V-K-V-V-A-Y-S-P-E-Q-E-G-K-V-F-F-G-A-W-V-E-I-E-N-D-E-G-E-T-M-K-F-R-I-V-G-Y-D-E-I-Y-G-R-N-D-Y-I-S-I-D-S-P-M-A-R-A-L-L-K-K-E-E-G-D-E-V-V-V-H-T-P-T-G-E-A-T-W-Y-V-S-S-I-R-Y-G-Q-G-V-S-T-D


### FUNCTION Sulfur carrier protein which probably makes part of a sulfur-relay system ### SEQUENCE -M-T-D-F-T-P-D-A-I-L-D-A-T-G-L-N-C-P-E-P-V-M-M-L-H-Q-H-V-R-N-L-A-A-G-G-L-L-K-V-I-A-T-D-P-S-T-R-R-D-I-P-K-F-C-N-F-L-G-H-E-L-L-Q-Q-Q-E-D-A-G-T-F-L-Y-W-I-R-K-K-A-D


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-T-I-E-E-R-V-K-K-I-V-A-E-Q-L-G-V-K-E-E-E-V-T-V-E-K-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-E-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-A-A-I-D-Y-V-K-A-H-Q-A


### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-L-P-L-L-L-A-S-S-S-A-Y-R-R-E-L-L-A-R-L-H-L-P-F-T-W-A-S-P-D-I-D-E-Q-R-L-D-G-E-P-P-V-E-L-V-R-R-L-A-R-Q-K-A-E-A-L-A-G-S-H-P-R-H-L-I-I-G-S-D-Q-V-A-V-L-G-E-Q-V-L-G-K-P-H-T-F-E-R-A-C-E-Q-L-L-E-C-S-G-Q-Q-V-S-F-L-T-G-L-A-L-L-N-S-A-T-G-Q-C-Q-V-D-C-V-P-F-T-V-T-L-R-E-L-S-R-E-Q-V-E-R-Y-V-A-A-E-Q-P-L-D-C-A-G-S-F-K-A-E-G-L-G-V-S-L-F-Q-S-T-H-G-C-D-A-T-S-L-I-G-L-P-L-I-R-L-V-D-M-L-T-K-E-G-V-M-V-P


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-K-T-G-K-E-L-K-P-G-T-V-L-R-I-D-N-D-P-W-L-V-Q-K-A-E-F-T-K-S-G-R-N-S-A-I-M-K-T-K-L-K-N-L-L-T-G-Y-K-T-E-T-V-Y-G-A-D-D-K-L-D-D-V-I-L-D-R-K-E-A-T-L-S-F-I-N-G-D-E-Y-T-F-M-D-T-T-D-Y-T-M-Y-E-L-N-A-E-D-I-E-A-V-L-P-Y-I-E-E-G-M-E-D-V-C-E-A-V-F-F-E-G-R-L-V-S-V-E-L-P-T-T-I-S-R-K-V-V-Y-T-E-N-A-A-R-G-D-T-S-G-K-V-M-K-P-A-K-L-A-N-G-T-E-I-S-V-A-D-F-I-Q-I-D-E-W-I-D-I-D-T-R-D-N-S-F-K-G-R-S-K-K


### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-N-L-F-D-F-F-R-G-R-Q-K-Q-T-S-A-S-V-A-K-E-R-L-Q-I-I-V-A-H-E-R-G-Q-R-S-E-P-D-Y-L-P-A-L-Q-K-E-L-L-E-V-I-R-K-Y-V-N-I-G-N-D-D-V-H-I-E-L-E-N-Q-G-S-C-S-I-L-E-L-N-I-T-L-P-D-R


### FUNCTION Modulates RecA activity ### SEQUENCE -M-S-A-V-L-D-T-P-V-A-I-R-R-T-A-M-D-L-L-A-R-R-E-H-G-R-V-E-L-T-R-K-L-R-Q-R-G-A-S-D-E-L-I-E-P-E-L-D-R-L-A-E-E-G-L-L-S-E-A-R-Y-L-E-S-F-I-R-Y-R-S-G-S-G-Y-G-P-A-R-I-R-E-E-L-C-Q-R-G-L-A-R-A-D-I-D-Q-A-L-R-E-S-E-V-N-W-S-E-R-M-R-D-V-W-Q-R-K-F-A-G-Q-R-P-Q-D-P-R-S-R-A-Q-Q-T-R-F-L-A-Y-R-G-F-P-M-D-M-I-G-R-L-L-S-G-R-D-L-D-D-Y


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-N-D-I-K-K-D-A-Q-E-R-M-G-K-S-I-E-A-L-S-R-N-L-A-A-I-R-T-G-R-A-H-P-S-I-L-D-S-V-K-V-T-A-W-G-S-E-M-P-L-N-Q-V-A-A-I-T-V-E-D-A-R-T-L-K-I-V-A-H-D-K-N-L-S-A-A-I-E-K-A-I-L-T-S-D-L-G-L-N-P-S-S-A-G-T-T-I-R-V-P-M-P-A-L-T-E-E-T-R-K-G-Y-T-K-Q-A-S-G-V-A-E-D-A-K-V-A-V-R-N-V-R-R-D-A-L-A-D-L-K-K-L-T-K-D-K-E-I-S-E-D-E-E-R-R-A-A-D-E-I-Q-K-L-T-D-K-F-V-A-E-V-D-A-A-F-K-A-K-E-K-D-L-M-A-V


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-T-N-K-I-I-Q-Q-L-E-A-E-Q-M-S-K-E-I-P-T-F-A-P-G-D-T-V-V-V-Q-V-K-V-K-E-G-E-R-S-R-L-Q-A-F-E-G-V-V-I-A-K-R-N-R-G-L-N-S-A-F-T-V-R-K-I-S-S-G-V-G-V-E-R-T-F-Q-T-Y-S-P-Q-I-D-S-L-A-V-K-R-R-G-D-V-R-K-A-K-L-Y-Y-L-R-D-L-S-G-K-A-A-R-I-K-E-K-L-S


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-N-A-T-P-E-K-A-D-D-L-I-V-V-G-K-I-F-S-V-H-G-V-R-G-E-V-K-V-Y-S-F-T-D-P-I-E-N-L-L-D-Y-P-R-W-T-L-R-H-E-G-K-V-K-Q-V-E-L-V-S-G-R-G-S-Q-K-G-L-V-V-K-L-K-G-L-D-D-R-D-E-A-R-L-L-S-G-Y-E-I-C-I-P-R-S-L-L-P-N-L-A-A-D-E-Y-Y-W-Y-Q-L-V-G-L-K-V-I-N-Q-D-E-Q-L-F-G-K-V-D-H-L-L-E-T-G-A-N-D-V-M-V-V-K-P-C-A-G-S-L-D-D-R-E-R-L-L-P-Y-T-E-Q-C-V-L-A-I-D-L-E-A-G-V-M-R-V-E-W-D-A-D-F


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-L-R-P-L-H-D-R-V-V-I-R-R-S-E-E-E-S-K-T-A-G-G-I-V-L-P-G-S-A-A-E-K-P-N-R-G-E-V-V-A-V-G-T-G-R-V-L-D-N-G-E-V-R-A-L-A-V-K-V-G-D-K-V-V-F-G-P-Y-S-G-S-N-T-V-K-V-D-G-E-D-L-L-V-M-A-E-N-E-I-L-A-V-V-E-G


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-T-A-K-P-E-T-V-K-R-E-W-F-V-V-D-A-A-G-Q-T-L-G-R-L-A-T-E-I-A-T-R-L-R-G-K-H-K-P-E-Y-T-P-H-V-D-T-G-D-Y-I-V-V-I-N-A-E-Q-V-R-V-T-G-A-K-S-S-D-K-M-Y-Y-S-H-S-G-F-P-G-G-I-K-E-I-N-F-E-K-L-I-A-K-A-P-E-R-V-I-E-T-A-V-K-G-M-L-P-K-N-P-L-G-R-D-M-Y-R-K-L-K-V-Y-A-G-A-A-H-P-H-T-A-Q-Q-P-Q-E-L-K-I


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-E-L-R-F-T-E-D-H-E-W-L-R-V-E-A-D-G-S-V-T-V-G-I-T-A-Y-A-Q-N-A-L-G-D-V-V-F-V-Q-L-P-E-L-Q-Q-Y-E-K-G-N-E-A-S-T-V-E-S-V-K-A-A-S-G-V-Y-M-P-L-T-G-E-V-V-E-V-N-G-Q-L-E-D-S-P-E-L-V-N-E-D-P-M-G-E-G-W-F-F-R-F-I-P-A-D-A-E-A-V-T-A-L-L-D-Q-D-A-Y-D-R-L-L-K-A-N-D-D-A


### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-G-T-P-C-H-Y-A-L-F-D-L-Q-P-S-F-R-L-D-L-D-K-L-A-T-R-Y-R-E-L-A-R-E-V-H-P-D-R-F-A-D-A-S-E-R-E-Q-R-I-A-L-E-K-S-A-A-L-N-D-A-Y-Q-T-L-R-S-A-P-R-R-A-R-Y-L-L-A-I-S-G-H-E-V-P-Q-E-V-T-V-H-D-P-D-F-L-L-Q-Q-M-Q-W-R-E-E-L-E-E-L-Q-D-E-A-D-L-D-G-V-G-V-F-K-K-R-L-K-A-A-Q-D-T-L-N-E-D-F-A-G-C-W-D-A-P-G-E-R-D-K-A-E-R-L-M-R-R-M-Q-F-L-D-K-L-A-Q-E-V-R-Q-L-E-E-R-L-D-D


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-T-E-F-T-L-N-A-Q-A-R-T-D-L-G-K-G-A-S-R-R-L-R-H-S-A-N-I-P-A-V-V-Y-G-G-N-Q-D-A-Q-S-L-T-I-L-A-K-E-I-T-K-L-F-E-N-E-A-A-F-S-H-V-L-E-L-N-V-D-G-A-K-Q-N-V-V-V-K-A-L-Q-R-H-P-A-K-G-F-I-M-H-A-D-F-V-R-V-V-A-G-Q-K-L-T-A-K-V-P-V-H-F-I-N-E-E-A-P-V-K-K-G-G-E-I-S-H-V-E-S-E-I-E-V-S-C-E-A-K-D-L-P-E-F-I-E-V-D-L-A-N-A-E-I-G-T-I-I-H-L-S-D-L-K-A-P-K-G-V-E-F-V-A-L-A-H-G-D-D-K-A-V-A-N-V-H-A-P-R-V-A-P-E-A-E-G-A-A-E


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-A-I-Q-L-I-V-G-L-G-N-P-G-P-E-Y-E-Q-T-R-H-N-A-G-A-L-F-V-E-R-L-A-S-A-Q-R-V-S-L-T-A-D-K-K-Y-F-G-L-T-A-K-F-S-H-Q-G-N-D-V-R-L-L-I-P-T-T-Y-M-N-R-S-G-Q-S-V-A-A-L-A-N-F-F-R-I-K-P-E-A-I-L-V-A-H-D-E-L-D-L-P-P-G-V-A-K-L-K-R-G-G-G-H-G-G-H-N-G-L-R-D-I-I-A-Q-L-G-N-Q-N-D-F-H-R-L-R-L-G-I-G-H-P-G-D-A-K-L-V-S-N-F-V-L-G-R-A-P-R-A-E-Q-E-K-L-D-A-S-I-D-F-A-L-G-V-L-P-D-V-L-A-G-D-F-A-K-A-M-R-E-L-H-S-Q-K-A


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-Y-A-V-I-V-T-G-G-K-Q-Y-K-V-A-E-G-E-F-L-K-I-E-K-L-E-V-A-T-G-E-S-V-T-F-D-R-V-L-L-V-A-N-G-E-E-V-T-I-G-A-P-V-V-A-G-A-K-V-V-A-E-V-V-S-Q-G-R-H-D-K-V-R-I-I-K-F-R-R-R-K-H-H-M-K-R-M-G-H-R-Q-W-F-T-E-I-K-I-T-G-I-Q-A


### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-S-Q-P-L-T-V-D-C-P-T-C-G-A-P-V-E-W-S-E-K-N-A-F-R-P-F-C-S-D-R-C-K-L-I-D-L-G-A-W-A-A-E-E-H-K-I-A-G-S-E-E-S-E-D-E-L-Y-S-G-D-L-E-P-R-H


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-T-P-S-A-K-K-R-A-K-Q-A-E-K-R-R-S-H-N-A-S-L-R-S-M-V-R-T-Y-I-K-N-V-V-K-A-I-D-A-K-D-A-E-K-A-Q-A-A-Y-V-L-A-V-P-V-I-D-R-M-A-D-K-G-I-I-H-K-N-K-A-A-R-H-K-G-R-L-N-G-H-I-K-A-L-K-E-A-A-A-A


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-R-K-K-A-S-L-D-F-E-Q-S-L-A-D-L-Q-A-L-V-E-R-L-E-N-G-E-L-S-L-E-E-S-L-A-A-F-E-Q-G-I-A-L-T-R-D-C-Q-G-A-L-A-Q-A-E-Q-K-V-Q-I-L-L-E-R-D-G-E-L-A-A-Q-P-F-D-A-E-P-E-A


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-I-S-D-E-S-D-R-F-N-P-R-D-P-K-P-A-D-A-G-K-P-S-K-S-A-K-R-R-E-A-R-K-L-A-T-Q-A-L-Y-Q-W-H-M-A-Q-H-S-L-N-E-I-E-A-Q-F-R-V-D-N-D-F-T-D-V-D-G-A-Y-F-R-E-I-L-H-G-V-P-A-I-K-G-E-I-D-K-A-L-V-P-C-M-T-I-A-L-E-E-L-D-P-V-E-L-A-V-L-R-L-S-T-W-E-L-I-K-R-V-D-V-P-Y-R-V-V-I-N-E-G-V-E-L-A-K-V-F-G-A-T-D-G-H-K-F-V-N-G-V-L-D-K-L-A-P-A-L-R-E-A-E-V-K-A-N-K-R


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-G-A-N-D-T-K-V-I-D-S-R-L-V-A-E-G-E-Q-V-R-R-R-R-E-C-V-A-C-G-E-R-F-T-T-F-E-T-A-E-L-V-L-P-R-L-I-K-Q-D-G-T-R-Q-P-F-D-E-E-K-L-R-A-G-M-Q-R-A-L-E-K-R-P-V-S-V-E-R-L-E-A-A-L-A-H-I-K-S-R-L-R-A-T-G-E-R-E-V-K-S-L-V-V-G-E-M-V-M-A-E-L-R-K-L-D-E-V-A-Y-I-R-F-A-S-V-Y-R-R-F-Q-D-L-D-E-F-R-E-E-I-D-R-L-A-R-E-P-A-K-E


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-A-R-G-V-N-K-V-I-L-V-G-T-C-G-Q-D-P-E-V-R-Y-L-P-N-G-N-A-V-T-N-L-S-L-A-T-S-E-Q-W-T-D-K-Q-S-G-Q-K-V-E-R-T-E-W-H-R-V-S-L-F-G-K-V-A-E-I-A-G-E-Y-L-R-K-G-S-Q-C-Y-I-E-G-K-L-Q-T-R-E-W-E-K-D-G-I-K-R-Y-T-T-E-I-I-V-D-I-N-G-T-M-Q-L-L-G-G-R-P-Q-G-Q-Q-Q-G-G-D-P-Y-N-Q-G-G-G-N-Y-G-G-G-Q-Q-Q-Q-Y-N-Q-A-P-P-R-Q-Q-A-Q-R-P-Q-Q-A-P-Q-R-P-A-P-Q-Q-P-A-P-Q-P-A-A-D-F-D-S-F-D-D-D-I-P-F


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-I-P-D-N-K-H-T-V-I-S-L-T-Y-I-Y-G-V-G-R-T-T-A-Q-K-I-C-A-D-A-G-V-N-P-A-A-K-I-K-D-L-S-D-E-Q-I-E-T-L-R-G-E-V-A-K-F-T-T-E-G-D-L-R-R-D-I-N-M-K-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-K-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-R-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-N-D-L-S-P-A-P-G-S-R-R-E-K-H-R-P-G-R-G-I-G-S-G-L-G-K-T-G-G-R-G-H-K-G-Q-T-S-R-S-G-G-S-I-A-P-G-F-E-G-G-Q-Q-P-L-H-R-R-L-P-K-F-G-F-V-S-L-K-A-M-D-R-A-E-V-R-L-S-E-L-A-K-V-E-G-D-V-I-S-V-Q-S-L-K-D-A-N-V-I-N-Q-H-I-Q-R-V-K-I-M-L-S-G-E-V-T-R-A-V-T-I-K-G-I-A-A-T-K-G-A-R-A-A-I-E-A-A-G-G-K-F-E-E


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-N-N-D-Q-K-R-D-E-G-Y-I-E-K-L-V-Q-V-N-R-V-A-K-T-V-K-G-G-R-I-F-T-F-T-A-L-T-V-V-G-D-G-K-G-R-V-G-F-G-R-G-K-S-R-E-V-P-A-A-I-Q-K-A-M-E-A-A-R-R-N-M-I-Q-V-D-L-K-G-T-T-L-Q-Y-A-T-K-A-A-H-G-A-S-K-V-Y-M-Q-P-A-S-E-G-T-G-I-I-A-G-G-A-M-R-A-V-L-E-V-A-G-V-Q-N-V-L-A-K-C-Y-G-S-T-N-P-V-N-V-V-Y-A-T-F-K-G-L-K-A-M-Q-S-P-E-S-I-A-A-K-R-G-K-S-V-E-E-I-F


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-T-D-K-K-V-I-R-L-R-R-A-R-K-A-R-L-K-M-H-E-L-E-V-V-R-L-C-V-F-R-S-S-Q-H-I-Y-A-Q-V-I-S-A-D-G-S-K-V-L-A-S-A-S-T-L-D-K-D-L-R-D-G-A-T-G-N-I-D-A-A-T-K-V-G-K-L-V-A-E-R-A-K-A-A-G-V-S-Q-V-A-F-D-R-S-G-F-K-Y-H-G-R-V-K-A-L-A-D-A-A-R-E-G-G-L-E-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-N-P-V-K-L-P-S-G-V-E-V-K-F-A-G-Q-Q-L-S-V-K-G-A-K-G-T-L-E-L-N-V-H-S-S-V-E-V-T-E-E-S-G-E-L-R-F-V-A-R-N-G-D-Q-Q-A-R-A-M-A-G-T-T-R-A-L-V-N-N-M-V-Q-G-V-S-Q-G-F-E-R-K-L-Q-L-V-G-V-G-Y-K-A-Q-A-K-G-T-V-L-N-L-A-L-G-F-S-H-P-V-D-Y-E-L-P-A-G-I-T-A-E-T-P-S-Q-T-D-I-L-I-K-G-I-D-K-Q-L-V-G-Q-V-A-A-E-I-R-D-F-R-P-P-E-P-Y-K-G-K-G-V-R-Y-A-D-E-V-V-R-R-K-E-A-K-K-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-L-A-D-M-L-T-R-I-R-N-A-Q-M-A-E-K-S-V-V-S-M-P-S-S-T-L-K-V-A-V-A-K-V-L-K-D-E-G-Y-I-A-G-Y-Q-V-T-G-E-A-K-P-S-L-S-I-E-L-K-Y-F-E-G-R-P-V-I-E-E-L-K-R-S-S-R-P-G-L-R-Q-Y-K-A-V-T-D-L-P-K-V-R-G-G-L-G-V-S-I-V-S-T-N-K-G-V-M-T-D-R-A-A-R-A-A-G-V-G-G-E-V-L-C-T-V-F


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-K-N-R-E-L-K-R-Q-L-T-V-A-K-F-A-K-K-R-A-E-L-K-A-T-I-V-N-L-N-A-S-P-E-E-R-F-A-A-V-V-A-L-Q-K-Q-P-R-D-A-S-A-S-R-L-R-N-R-C-R-L-T-G-R-P-H-G-V-Y-R-K-F-G-L-G-R-N-M-L-R-Q-A-A-M-R-G-D-V-P-G-L-V-K-A-S-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-R-L-K-E-I-Y-R-N-E-I-A-P-K-L-K-E-E-L-K-L-S-N-V-M-E-V-P-R-V-T-K-I-T-L-N-M-G-L-G-E-A-I-G-D-K-K-V-I-E-H-A-V-A-D-L-E-K-I-T-G-Q-K-P-V-V-T-F-A-R-K-S-I-A-G-F-K-V-R-E-G-W-P-I-G-V-K-V-T-L-R-S-D-K-M-Y-E-F-L-D-R-L-L-A-I-S-L-P-R-V-R-D-F-R-G-L-N-A-K-S-F-D-G-R-G-N-Y-S-M-G-V-K-E-Q-I-I-F-P-E-I-D-Y-D-K-I-D-A-L-R-G-L-D-I-T-L-T-T-T-A-R-S-D-D-E-G-R-A-L-L-R-A-F-K-F-P-F-R-N


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-K-I-R-R-D-D-E-I-I-V-I-A-G-K-D-K-G-K-R-G-K-V-L-K-V-L-A-D-D-R-L-V-I-G-G-V-N-L-V-K-R-H-T-K-P-N-P-M-A-G-V-Q-G-G-I-V-E-K-E-A-P-L-H-A-S-N-V-A-I-F-N-G-E-T-N-K-A-D-R-V-G-F-K-V-E-D-G-K-K-I-R-V-F-K-S-T-Q-K-A-V-D-A


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-T-Q-S-M-L-D-V-A-D-N-S-G-A-R-R-V-M-C-I-K-V-L-G-G-S-H-R-R-Y-A-G-I-G-D-I-I-K-V-T-V-K-E-A-I-P-R-G-K-V-K-K-G-Q-V-M-T-A-V-V-V-R-T-R-H-G-V-R-R-A-D-G-S-I-I-R-F-D-G-N-A-A-V-L-L-N-N-K-Q-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-T-E-K-F-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-A-E-A-E-K-T-V-R-T-L-T-G-R-V-V-S-D-K-M-D-K-T-I-T-V-L-I-E-R-R-V-K-H-P-I-Y-G-K-Y-V-K-R-S-T-K-L-H-A-H-D-E-A-N-Q-C-K-I-G-D-K-V-S-I-R-E-T-R-P-L-A-K-T-K-S-W-A-L-V-E-V-L-E-R-A-V-E-V


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-Q-P-K-R-T-K-F-R-K-Q-M-T-G-H-N-R-G-L-A-L-R-G-S-K-V-S-F-G-E-F-A-L-K-A-V-A-R-G-R-L-T-A-R-Q-I-E-S-A-R-R-A-L-T-R-H-V-K-R-G-G-K-I-W-I-R-V-F-P-D-K-P-I-S-K-K-P-L-E-V-R-M-G-K-G-K-G-S-V-E-Y-W-V-A-Q-I-Q-P-G-K-V-L-Y-E-I-E-G-V-S-E-E-L-A-R-E-A-F-A-L-A-A-A-K-L-P-L-A-T-S-F-V-K-R-T-V-M


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-V-A-A-K-L-S-G-A-R-I-S-A-Q-K-A-R-L-V-A-D-Q-I-R-G-K-K-V-G-E-A-L-N-L-L-A-F-S-S-K-K-A-A-E-I-M-K-K-V-L-E-S-A-V-A-N-A-E-H-N-E-G-A-D-V-D-D-L-K-V-S-T-V-F-V-N-E-G-R-S-L-K-R-I-M-P-R-A-K-G-R-A-D-R-I-V-K-R-S-C-H-I-T-V-K-V-A-D-K


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-P-R-S-L-K-K-G-P-F-I-D-L-H-L-L-K-K-V-E-V-A-V-E-K-N-D-R-K-P-V-K-T-W-S-R-R-S-M-I-L-P-Q-M-V-G-L-T-I-A-V-H-N-G-R-Q-H-V-P-V-L-V-N-E-D-M-V-G-H-K-L-G-E-F-A-G-T-R-T-Y-R-G-H-V-A-D-K-K-A-K-R


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-Q-E-R-V-F-K-V-L-L-G-P-H-V-S-E-K-A-T-V-L-A-E-K-K-G-Q-F-V-F-K-V-A-T-D-A-T-K-L-E-I-K-K-A-V-E-G-L-F-N-V-K-V-E-N-V-S-T-V-N-V-L-G-K-T-K-R-T-A-R-G-L-G-K-R-N-D-W-K-K-A-I-V-S-L-Q-P-G-Q-D-L-D-F-S-S-S-A-E


### FUNCTION One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA It is important during the early stages of 50S assembly It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-Q-L-N-V-N-D-A-Q-A-I-E-V-S-E-L-T-F-G-G-E-F-N-E-T-L-V-H-Q-A-V-V-A-Y-M-A-G-G-R-Q-G-T-K-Q-Q-K-T-R-S-D-V-A-G-G-G-K-R-P-W-R-Q-K-G-T-G-R-A-R-A-G-T-T-R-G-P-I-W-R-G-G-G-V-T-F-A-A-R-P-Q-D-H-S-Q-K-L-N-K-K-M-Y-R-A-A-L-R-S-I-L-A-E-L-V-R-S-D-R-L-V-V-V-Q-D-F-A-V-E-A-P-K-T-K-D-L-L-N-K-L-N-G-M-G-L-S-D-V-L-I-V-S-D-A-V-D-Q-N-L-Y-L-A-A-R-N-L-P-H-V-D-V-R-D-V-Q-G-S-D-P-V-S-L-I-A-Y-E-K-V-L-I-T-V-S-A-V-K-K-F-E-E-L-L-G


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-N-Q-Q-I-R-I-R-L-K-A-F-D-H-R-L-I-D-Q-S-T-Q-E-I-V-E-T-A-K-R-T-G-A-Q-V-R-G-P-I-P-L-P-T-R-K-E-R-F-T-V-L-V-S-P-H-V-N-K-D-A-R-D-Q-Y-E-I-R-T-H-K-R-V-L-D-I-V-Q-P-T-D-K-T-V-D-A-L-M-K-L-D-L-A-A-G-V-E-V-Q-I-S-L-G


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-R-R-V-A-A-K-R-E-I-L-D-D-P-K-Y-G-S-Q-I-L-A-K-F-M-N-H-V-M-E-S-G-K-K-A-V-A-E-R-I-V-Y-G-A-L-D-T-V-K-A-R-K-N-S-D-P-L-E-I-F-E-K-A-L-D-A-I-A-P-L-V-E-V-K-S-R-R-V-G-G-A-T-Y-Q-V-P-V-E-V-R-P-S-R-R-N-A-L-A-M-R-W-L-V-D-Y-A-R-K-R-G-E-K-S-M-A-L-R-L-A-G-E-L-L-D-A-A-E-G-K-G-A-A-V-K-K-R-E-D-V-H-R-M-A-E-A-N-K-A-F-S-H-Y-R-F


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-A-T-I-N-Q-L-V-R-Q-P-R-K-R-S-V-E-K-S-D-V-P-A-L-Q-N-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-C-R-V-R-L-T-N-G-F-E-V-S-S-Y-I-G-G-E-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-T-V-R-G-S-L-D-T-S-G-V-K-G-R-N-Q-G-R-S-K-Y-G-T-K-R-P-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-I-K-L-E-D-K-K-A-I-V-A-E-V-N-E-A-A-K-V-A-L-S-A-V-V-A-D-A-R-G-V-T-V-S-A-M-T-G-L-R-K-E-A-R-E-A-G-V-Y-V-R-V-V-R-N-T-L-L-K-R-A-V-E-G-T-E-F-S-I-L-N-D-A-F-K-G-P-T-L-I-A-F-S-N-E-H-P-G-A-A-A-R-L-F-K-E-F-A-K-G-Q-D-K-F-E-I-K-A-A-A-F-D-G-N-F-I-A-A-N-Q-I-D-V-L-A-T-L-P-T-R-D-E-A-I-A-R-L-M-S-V-I-Q-G-A-T-S-K-L-A-R-T-L-A-A-I-R-D-Q-K-E-A-T-A-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-Q-A-Y-I-K-L-Q-V-K-A-G-Q-A-N-P-S-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-E-F-C-K-A-F-N-A-R-T-Q-G-Q-E-A-G-L-P-T-P-V-I-I-T-V-Y-S-D-R-S-F-T-F-E-T-K-S-T-P-A-S-V-L-L-K-K-A-A-G-L-T-S-G-S-A-R-P-N-T-V-K-V-G-T-V-T-R-A-Q-L-E-D-I-A-K-A-K-Q-A-D-L-T-A-A-D-L-D-A-A-V-R-T-I-A-G-S-A-R-S-M-G-L-N-V-E-G-V


### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-V-E-T-F-T-P-T-G-L-E-F-T-H-G-A-A-Q-K-V-K-N-L-V-N-E-E-G-N-E-R-L-K-L-R-V-F-V-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-D-V-A-E-D-D-T-I-V-E-R-E-G-V-S-L-V-V-D-P-M-S-F-Q-Y-L-A-G-A-E-V-D-Y-Q-E-G-L-E-G-S-R-F-V-I-K-N-P-N-A-A-T-T-C-G-C-G-S-S-F-S-I


### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-S-E-F-K-R-I-P-P-E-Q-A-L-E-L-R-K-K-E-G-A-V-V-V-D-I-R-D-P-Q-A-F-A-A-G-H-I-T-G-A-R-H-L-D-N-H-S-V-A-D-F-I-R-N-A-D-L-D-A-P-T-L-V-V-C-Y-H-G-N-S-S-Q-S-A-A-A-Y-L-V-G-Q-G-F-S-D-V-Y-S-V-D-G-G-F-E-L-W-R-A-T-Y-P-A-E-T-A-Q-G-N-A-E


### FUNCTION Required for coenzyme pyrroloquinoline quinone ### SEQUENCE -M-W-T-K-P-A-Y-T-D-L-R-I-G-F-E-V-T-M-Y-F-A-N-R


### FUNCTION Probably forms a two-component reduced flavin mononucleotide-dependent monooxygenase by binding to SsuD Required for growth on aliphatic sulfonates or methionine but not arylsulfonates ### SEQUENCE -M-L-V-V-S-I-G-G-S-P-S-L-R-S-R-S-G-V-L-L-E-R-S-R-Q-W-L-Q-D-R-G-V-E-V-V-T-F-Q-V-R-D-F-P-A-E-D-L-L-H-A-R-F-D-S-P-H-V-Q-H-F-Q-Q-L-V-A-Q-A-D-G-L-I-V-S-T-P-V-Y-K-A-S-F-S-G-A-L-K-T-L-L-D-L-L-P-E-R-A-L-A-H-K-I-V-L-P-I-A-T-G-G-S-I-A-H-M-L-A-V-D-Y-A-L-K-P-V-L-S-A-L-K-A-Q-E-T-L-Q-G-I-F-A-D-D-S-Q-V-A-Y-A-E-G-T-K-P-A-Q-L-V-Q-A-L-E-E-R-L-H-D-S-L-E-T-F-H-V-A-L-A-R-R-P-R-P-V-A-P-G-V-L-N-E-R-L-I-S-A-R-W-S-I


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-I-L-N-I-L-E-F-P-D-P-R-L-R-T-L-A-K-P-V-T-E-F-D-D-A-L-R-Q-L-I-D-D-M-F-E-T-M-Y-E-A-P-G-I-G-L-A-A-T-Q-V-N-V-H-K-Q-V-V-V-M-D-L-S-E-D-R-S-E-P-R-V-F-I-N-P-S-V-E-E-L-T-H-D-M-G-Q-Y-Q-E-G-C-L-S-V-P-G-F-Y-E-N-V-D-R-P-L-R-V-R-V-K-A-Q-D-R-D-G-K-P-F-E-L-E-C-E-G-L-L-A-V-C-V-Q-H-E-F-D-H-L-N-G-K-L-F-V-D-Y-L-S-Q-L-K-R-D-R-I-K-K-K-L-E-K-Q-H-R-Q-Q-A


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-R-K-S-Y-R-V-K-K-E-T-E-F-Q-Q-V-F-E-T-R-N-S-Y-A-N-R-Q-F-V-I-Y-V-L-E-K-P-G-Q-P-H-F-R-V-G-I-S-V-G-K-K-I-G-N-A-V-A-R-N-W-V-K-R-R-I-R-Q-S-I-T-E-L-K-P-Q-L-K-Q-D-A-D-F-L-V-I-A-R-P-T-V-A-G-K-S-Q-A-E-T-K-A-Y-L-S-H-A-L-K-L-A-H-L-L-D-N-D


### FUNCTION May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor ### SEQUENCE -M-E-K-P-E-Q-K-L-L-L-Y-K-L-S-D-R-L-F-A-A-I-Q-K-N-L-Q-L-E-R-R-Q-A-L-L-V-K-L-G-I-D-T-V-L-N-V-I-P-K-L-I-I-T-I-I-L-A-L-L-L-H-E-L-V-P-V-L-V-F-M-G-S-F-L-V-L-R-G-F-A-Y-G-R-H-L-E-S-D-L-L-C-T-I-L-T-A-V-T-F-V-G-V-P-Y-L-I-Q-F-T-D-G-I-P-E-L-F-R-F-I-L-C-L-L-L-T-V-P-I-G-M-F-S-P-A-V-T-R-K-N-P-I-K-S-Q-S-L-K-R-A-L-K-H-K-A-I-I-T-S-L-V-F-S-F-L-Q-F-L-V-S-N-N-L-G-T-I-I-V-V-S-L-L-L-V-F-T-L-I-V-P-L-K-G-G-K-S-D-E-A-E-N-V


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-L-D-N-L-T-I-A-S-R-Y-S-K-A-L-F-E-L-A-V-E-K-D-Q-T-E-A-F-L-A-E-L-K-Q-L-R-Q-V-F-V-D-N-P-Q-L-A-E-V-L-S-G-S-L-L-P-V-D-Q-K-Q-T-T-L-S-T-L-T-D-H-A-S-E-Y-I-K-N-F-I-Q-M-L-Y-D-Y-G-R-M-S-N-L-V-G-I-V-D-A-F-E-A-R-F-D-E-S-R-K-I-V-H-A-E-V-T-S-A-V-K-L-S-D-E-Q-A-D-A-I-A-K-A-F-A-K-R-V-G-A-N-Q-V-V-L-S-R-K-V-D-E-A-I-I-G-G-V-I-V-K-S-N-N-Q-T-F-D-G-S-V-A-L-Q-L-T-N-L-R-R-A-L-I-N-N


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-D-N-A-K-S-L-T-V-S-I-V-T-P-D-G-Q-V-Y-E-N-K-T-P-M-L-I-V-R-T-I-D-G-E-L-G-I-L-P-N-H-I-P-V-I-A-S-L-A-I-D-E-V-R-I-K-Q-L-E-S-D-Q-E-D-D-E-I-A-V-N-G-G-F-V-E-F-S-N-N-T-A-T-I-V-A-D-S-A-E-R-Q-N-D-I-D-V-A-R-A-E-N-A-R-K-R-A-E-T-R-I-Q-N-A-Q-Q-K-H-D-D-A-E-L-A-R-A-Q-V-A-L-R-R-A-M-N-R-L-N-V-A-R-H


### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-R-R-L-L-M-K-G-I-R-F-Y-Q-R-A-F-S-A-F-S-P-A-H-C-R-Y-Y-P-T-C-S-N-Y-T-L-E-A-I-N-R-F-G-A-V-K-G-V-L-M-G-V-A-R-I-L-R-C-Q-P-L-V-K-G-G-F-D-P-V-P-A-H-F-S-L-R-R-N-P-Q-Y-K-E-E-D-H-R-G-K-K-R


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-K-L-M-G-L-D-V-G-S-R-T-V-G-V-A-I-S-D-A-F-G-W-T-A-Q-G-V-E-I-I-R-I-N-E-D-A-E-E-F-G-I-D-R-V-A-E-L-V-E-E-L-D-A-G-G-F-V-L-G-L-P-K-N-M-N-N-T-L-G-P-R-A-E-A-A-Q-H-Y-G-E-L-L-T-A-R-F-H-L-P-V-D-F-E-D-E-R-L-T-T-V-E-A-E-R-M-L-V-E-E-A-N-T-S-R-K-K-R-K-K-V-I-D-K-L-A-A-S-L-I-L-Q-N-Y-L-D-R-H-G-K-L-T-Q-E


### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-I-L-Y-T-A-P-S-C-T-S-C-R-K-A-K-A-W-L-Q-T-H-D-I-D-F-Q-E-H-N-L-F-T-E-P-L-S-I-E-K-I-K-Q-I-L-Q-L-T-E-S-G-T-E-E-I-I-S-T-R-S-K-A-F-Q-Q-L-N-V-D-I-N-D-L-S-L-N-E-L-F-D-M-I-T-H-D-P-S-L-L-R-R-P-I-M-L-D-E-K-R-L-Q-V-G-Y-N-E-D-E-I-R-R-F-L-P-R-K-I-R-T-L-E-L-L-R-A-Q-Q-L-A-N-M


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-E-K-R-I-E-A-T-V-A-K-Y-A-E-R-R-Q-A-L-K-A-A-G-N-Y-T-E-L-A-K-L-P-R-N-A-S-P-V-R-I-H-R-R-D-S-L-D-G-R-P-H-A-Y-L-R-K-F-G-M-S-R-L-N-F-R-R-L-A-H-A-G-Q-I-P-G-V-K-K-A-S-W


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-G-F-I-S-N-F-F-G-V-G-D-S-D-S-Q-Y-E-E-P-T-E-A-S-Q-A-A-A-P-T-E-S-A-T-N-T-R-S-T-P-K-V-V-P-M-Q-G-G-K-S-V-N-S-K-I-A-L-F-E-P-K-I-Y-S-D-V-K-E-I-A-T-Q-L-L-K-N-Q-A-V-I-I-N-F-D-H-V-D-D-E-M-A-R-R-I-V-D-F-L-T-G-T-V-F-A-I-N-G-E-I-E-R-I-G-D-E-I-F-L-C-I-P-E-N-Y-E-V-S-G-S-T-T-S-Q-F-D-T-S-K-L


### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-Y-Y-Q-E-T-K-E-R-N-P-Q-R-E-T-T-Q-S-L-Y-L-E-A-E-T-E-V-A-A-R-T-L-V-E-D-N-T-D-H-N-I-E-F-I-E-P-L-E-G-N-F-L-D-Y-E-Q-K-N-P-E-Y-H-L-T-E-F-N-K


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-K-M-R-D-I-I-R-E-G-N-H-T-L-R-A-E-A-K-Q-V-K-F-P-L-S-E-A-D-Q-K-L-A-N-D-M-M-E-Y-L-E-N-S-Q-D-P-E-L-A-K-K-Y-G-L-R-A-G-V-G-L-A-A-P-Q-V-D-V-S-E-Q-M-A-A-V-L-V-P-S-E-N-E-D-D-E-P-V-F-K-D-V-I-I-N-P-V-I-I-S-H-S-V-Q-P-G-A-L-T-E-G-E-G-C-L-S-V-D-R-D-I-A-G-Y-V-I-R-H-D-R-I-T-L-R-Y-Y-N-M-A-G-E-E-K-K-I-R-L-K-N-Y-P-A-I-V-C-Q-H-E-I-D-H-L-H-G-I-L-F-Y-D-H-I-N-G-D-N-P-F-A-A-D-D-D-L-V-L-I-S


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-I-I-K-S-A-I-E-R-V-K-T-N-N-K-A-N-V-R-N-T-A-Q-M-S-A-M-R-T-A-V-K-K-F-E-A-A-K-T-A-G-A-D-N-V-D-D-L-Y-L-A-A-T-S-A-V-D-K-A-A-S-K-G-L-I-K-R-N-K-A-A-R-D-K-S-R-M-A-A-R-Y-A-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-R-E-K-K-T-E-L-I-N-K-Y-A-R-H-E-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-E-D-I-N-E-L-N-E-H-L-R-V-H-K-K-D-F-H-S-Q-R-G-L-M-K-K-I-G-H-R-R-N-L-L-A-Y-L-R-K-E-D-V-N-R-Y-R-D-L-I-Q-S-L-G-L-R-R


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-E-V-H-N-V-E-L-V-M-S-A-V-A-P-S-Q-Y-P-T-T-G-F-P-E-I-G-L-A-G-R-S-N-V-G-K-S-S-L-I-N-V-L-I-N-R-N-S-Y-A-R-T-S-S-Q-P-G-K-T-Q-T-L-N-F-Y-K-V-E-D-Q-L-Y-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-K-E-R-E-K-W-G-Q-M-I-E-T-Y-L-T-S-R-E-T-L-R-G-V-V-I-L-V-D-A-R-H-A-P-T-K-D-D-V-A-M-Y-E-W-M-R-Y-Y-E-M-P-L-L-V-V-A-T-K-S-D-K-I-P-R-G-K-W-N-K-Q-E-S-L-I-K-K-T-L-N-F-Q-A-E-D-D-F-I-A-F-S-A-K-T-K-E-G-K-D-A-V-W-Q-W-I-E-A-H-T-V-G-G-N


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-A-L-D-L-K-K-Y-V-A-S-I-P-D-Y-P-E-P-G-I-I-F-R-D-I-S-P-L-M-A-D-G-E-A-Y-R-E-A-T-D-Q-I-V-Q-F-A-R-D-K-H-V-D-M-I-V-G-P-E-A-R-G-F-I-V-G-C-P-V-A-Y-E-L-G-V-G-F-A-P-A-R-K-K-G-K-L-P-R-E-T-V-K-A-T-Y-D-L-E-Y-G-Q-S-A-L-Y-L-H-K-D-A-I-K-P-G-Q-N-V-L-V-T-D-D-L-L-A-T-G-G-T-I-S-A-T-I-Q-M-V-E-E-L-G-G-N-V-V-G-T-A-F-L-V-E-L-K-E-L-H-G-R-D-K-I-K-D-Y-D-M-L-S-L-M-Q-F


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-I-T-E-P-I-L-K-E-A-Q-E-R-M-K-K-A-E-A-A-L-Q-R-E-L-G-N-I-R-A-G-R-A-N-A-S-L-L-N-R-I-S-A-D-Y-Y-G-A-Q-T-P-L-N-Q-M-A-A-I-T-V-P-E-P-R-V-L-M-V-T-P-F-D-K-S-A-L-K-E-I-E-K-A-I-L-A-S-D-L-G-I-S-P-A-N-D-G-S-A-I-R-L-V-I-P-Q-L-T-E-E-R-R-K-E-L-A-K-D-V-K-A-E-G-E-R-A-K-V-A-V-R-N-V-R-R-D-A-M-E-A-L-K-K-G-H-K-D-G-Q-F-T-D-D-Q-L-H-Q-L-E-D-Q-A-Q-K-L-T-D-Q-A-G-K-D-V-D-A-I-V-A-D-K-E-K-E-I-L-E-G


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-S-S-N-V-V-E-T-I-Q-P-V-A-A-A-I-V-S-A-H-Q-F-E-L-V-D-L-E-F-V-R-E-G-Q-S-W-Y-L-R-L-Y-I-D-K-P-G-G-I-N-I-E-E-C-A-M-V-S-D-E-L-S-E-K-L-D-A-M-E-P-D-P-I-P-Q-A-Y-F-L-E-V-S-S-P-G-A-E-R-P-L-K-K-E-A-D-F-Q-N-A-I-G-K-Y-V-H-V-G-L-Y-Q-K-L-D-G-K-K-I-F-E-G-D-L-T-A-V-T-P-T-T-L-T-I-D-Y-L-D-K-T-R-H-K-T-V-T-I-N-R-E-Q-I-S-Q-A-R-L-A-V-K-F


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-Q-H-Y-R-V-G-R-L-E-Q-E-I-E-R-E-V-N-D-I-L-L-K-R-V-R-D-P-R-V-A-G-V-T-I-T-G-V-T-V-T-G-D-L-Q-Q-A-T-I-Y-Y-S-I-L-S-D-K-A-S-D-G-E-K-T-A-A-G-L-A-K-A-T-G-L-I-R-S-E-L-G-S-R-L-S-I-Y-K-T-P-E-L-T-F-E-R-D-N-S-V-Q-Y-G-S-R-I-D-E-L-I-N-N-L-K-R-Q-D


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-K-K-S-T-R-T-T-P-E-D-S-Q-A-S-T-T-D-S-A-A-T-S-T-A-S-E-A-T-Q-A-A-T-S-A-T-D-D-Q-A-E-Q-T-T-A-V-D-P-T-Q-Q-I-T-D-L-K-A-Q-L-D-A-K-D-D-Q-L-L-R-A-Q-A-E-I-V-N-M-Q-N-R-N-K-K-E-Q-A-A-L-L-K-Y-D-G-Q-A-L-A-K-D-V-L-P-V-L-D-N-L-E-R-A-L-A-T-P-A-D-D-E-A-A-Q-Q-L-K-K-G-V-E-M-V-Y-G-H-L-Q-D-A-L-K-K-H-G-V-T-E-V-A-A-A-G-E-K-F-D-P-N-I-H-Q-A-V-Q-T-V-P-V-D-D-D-H-P-A-D-T-V-V-Q-V-L-Q-R-G-Y-L-L-K-D-R-T-L-R-P-A-M-V-V-V-A-Q


### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid  by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-T-M-D-D-T-K-A-T-V-L-S-I-L-A-D-L-T-G-E-D-V-S-S-N-M-D-V-N-L-F-D-E-G-I-L-D-S-M-G-S-V-Q-L-L-L-E-L-Q-N-Q-L-G-I-E-V-P-V-S-E-F-Q-R-S-E-W-D-T-P-A-K-I-V-A-K-V-E-N-L-Q


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-D-L-E-L-Y-D-Q-T-T-T-G-A-Q-P-E-Q-L-Q-L-I-R-D-L-I-D-L-A-G-Q-T-L-K-L-R-D-D-T-E-V-S-V-T-L-M-N-N-D-A-I-Q-K-I-N-E-Q-Y-R-G-V-D-R-P-T-D-V-I-S-F-A-M-H-D-D-D-E-D-D-L-I-V-M-D-P-E-M-A-A-E-M-P-L-N-L-G-D-I-M-I-S-V-D-K-V-S-E-Q-A-A-F-L-N-H-S-E-A-R-E-L-G-Y-L-V-V-H-G-F-L-H-L-N-G-Y-D-H-L-Q-P-A-D-E-T-E-M-F-T-L-Q-R-Q-I-L-D-A-Y-G-L-E-K


### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-T-N-I-E-Q-I-E-G-L-L-F-V-A-G-D-E-G-I-T-V-A-E-I-E-H-A-T-G-F-A-K-P-A-I-T-T-M-L-T-Q-L-A-T-K-Y-Q-A-D-P-D-S-A-L-M-I-L-S-T-A-N-T-Y-R-L-A-T-K-A-A-V-A-P-V-L-K-R-Y-F-E-A-P-L-T-T-S-L-S-Q-A-S-L-E-V-L-A-I-I-A-Y-R-Q-P-L-T-R-I-E-I-D-E-I-R-G-V-H-S-G-S-T-I-Q-K-L-V-L-R-Q-L-V-T-E-T-G-R-L-S-E-P-G-R-P-I-L-Y-G-T-T-E-L-F-L-D-Y-F-G-L-K-S-L-D-D-L-P-A-I-D-L-A-A-L-S-D-A-E-H-P-A-P-E-T-D-L-F-L-N-A-F-Q-D-K-L-Q-A-E-R-E-D-E


### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-A-K-R-N-F-T-P-K-D-I-L-Q-K-E-F-K-P-K-M-R-G-Y-D-P-A-D-V-D-G-F-L-D-N-V-I-K-D-Y-E-S-F-T-K-D-N-Q-Q-L-S-D-E-N-E-R-L-R-A-K-V-D-E-L-T-K-Q-V-A-V-G-A-T-S-P-S-S-Q-P-T-S-T-V-T-N-M-D-I-L-K-R-L-S-N-L-E-R-H-V-F-G-A-Q-L-D-N-N-Q-N-E-S-H-R-L


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-R-Q-N-Q-L-I-E-K-I-T-N-E-Q-L-R-T-D-I-P-D-F-R-A-G-D-T-V-R-V-H-A-R-V-V-E-G-T-R-E-R-I-Q-L-F-E-G-V-V-I-K-R-H-G-S-G-I-S-E-T-Y-T-V-R-K-I-S-N-G-V-G-V-E-R-T-F-P-L-H-T-P-R-V-A-A-I-D-V-V-R-Q-G-R-V-R-R-A-K-L-Y-Y-L-R-N-L-H-G-K-A-A-R-I-P-E-R-R-R-G


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-D-Y-Y-R-V-G-T-L-V-N-T-H-G-I-R-G-E-V-K-V-V-V-V-T-D-F-P-E-E-R-F-K-V-G-Q-Q-L-S-L-F-K-T-P-D-E-T-T-G-G-I-T-V-K-I-A-K-A-R-E-Q-K-G-L-Y-F-L-T-F-E-G-L-D-N-I-N-D-V-E-R-Y-K-G-W-T-I-K-V-P-A-E-A-L-H-A-L-P-A-G-E-Y-Y-Y-H-Q-I-V-G-L-Q-V-V-T-T-A-D-E-P-L-G-T-I-K-E-I-L-S-P-G-A-N-D-V-W-V-V-K-R-D-H-G-Q-S-D-V-L-L-P-K-I-P-Q-V-I-K-D-V-D-L-D-A-G-V-V-T-V-E-L-M-E-G-L-I-D


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-I-L-Y-P-S-V-D-D-L-L-K-Q-V-N-S-R-Y-S-L-I-M-L-A-S-K-R-A-H-E-L-D-A-G-A-A-P-M-L-S-E-Y-K-S-V-K-T-I-G-R-A-M-E-E-I-A-A-G-D-L-M-I-D-P-D-E-T-D-K-D


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-A-E-Q-P-T-F-E-Q-N-L-S-Q-L-E-T-I-V-N-Q-L-E-Q-G-D-V-P-L-E-Q-A-L-D-Q-F-Q-K-G-V-A-L-S-K-Q-L-Q-A-T-L-E-G-A-E-K-T-L-T-K-M-M-N-E-N-G-D-E-V-P-F-E-Q-A-D-A-N-E


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-S-L-T-R-H-E-I-R-E-K-A-F-Q-A-L-F-A-L-N-A-N-P-D-A-D-E-N-Q-L-F-Q-Q-L-L-N-P-E-E-T-D-A-V-E-I-P-A-Y-L-S-T-L-V-T-G-V-R-E-H-Q-V-E-L-D-A-Q-I-Q-P-Y-L-S-Q-K-W-S-L-D-R-L-A-K-T-D-L-I-I-L-R-I-A-F-F-E-L-Q-F-V-D-D-V-P-T-K-V-A-V-N-E-A-I-E-L-T-K-A-F-S-D-D-R-S-R-K-F-V-S-G-V-L-G-K-V-V-K-N-Q-A-N


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-T-A-D-F-K-N-G-L-T-I-E-V-D-N-A-I-W-R-I-V-E-F-Q-H-V-K-P-G-K-G-G-A-F-V-R-S-K-L-K-N-L-R-T-G-A-V-Q-D-K-T-F-R-A-G-A-R-M-E-Q-A-P-I-E-K-S-T-M-Q-Y-L-Y-A-D-G-D-S-Y-V-F-M-N-T-E-T-Y-E-Q-I-E-I-P-G-D-H-I-Q-D-E-L-K-F-L-K-E-N-M-E-V-Q-V-T-L-Y-K-G-E-V-L-G-I-D-L-P-N-T-V-T-L-E-V-A-E-T-E-P-G-I-K-G-D-T-A-S-G-G-S-K-P-A-T-L-E-T-G-A-I-I-Q-V-P-F-F-V-K-A-G-D-K-L-I-V-N-T-V-D-S-T-Y-V-S-R-A


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-I-V-T-G-G-K-Q-Y-K-V-E-A-G-Q-A-I-Y-V-E-K-L-D-A-A-A-G-D-K-V-T-F-D-Q-V-V-F-V-G-G-D-T-T-K-V-G-T-P-T-V-D-G-A-T-V-E-G-T-V-E-K-Q-G-R-D-R-K-V-V-T-F-K-Y-K-A-K-K-G-Q-H-T-K-K-G-H-R-Q-P-Y-T-K-V-T-I-D-T-I-N-A


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-E-D-K-T-Y-P-M-T-E-E-G-K-V-K-L-E-K-E-L-E-D-L-R-I-N-Q-R-P-E-I-I-N-R-I-K-I-A-R-S-Y-G-D-L-S-E-N-S-E-Y-E-S-A-K-N-E-Q-S-L-L-E-N-R-I-K-T-V-E-H-M-L-Q-Y-A-E-I-I-D-S-D-K-I-D-E-T-E-V-S-V-G-K-I-V-T-F-K-E-L-P-D-E-E-P-E-S-Y-T-I-V-G-A-A-E-A-D-P-M-V-G-K-I-S-N-D-S-P-I-A-K-G-L-I-G-H-H-V-D-E-E-V-A-I-N-I-P-A-G-T-M-T-V-K-I-L-K-V-E-N-A


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-G-G-T-V-T-R-K-R-R-K-R-I-L-K-L-A-K-G-Y-R-G-A-K-H-I-Q-F-K-V-A-K-D-Q-V-M-K-S-Y-L-Y-A-F-R-D-R-R-R-R-K-S-D-F-R-R-L-W-I-A-R-I-N-A-A-A-R-I-N-D-I-S-Y-S-Q-L-M-H-G-L-K-L-A-N-V-D-V-N-R-K-M-L-A-D-L-A-V-N-D-A-D-A-F-K-A-L-V-D-T-A-K-K-A-L-A


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-T-I-A-K-D-S-M-V-N-D-G-I-R-A-R-E-V-R-L-I-A-S-D-G-E-Q-L-G-V-K-S-R-Q-E-A-M-Q-I-A-E-D-A-S-L-D-L-V-L-V-A-P-K-A-K-P-P-V-A-R-I-M-D-Y-G-K-Y-R-F-E-Q-Q-K-K-D-R-E-A-R-K-K-Q-K-V-V-S-I-K-E-V-R-L-S-P-A-I-D-T-N-D-F-N-T-K-L-K-H-A-E-K-F-L-S-K-G-D-K-V-R-V-S-I-R-F-K-G-R-A-I-T-H-K-D-I-G-R-Q-V-L-N-R-M-I-E-A-T-K-E-F-S-T-V-E-A-Y-P-K-M-D-G-R-S-M-F-L-V-L-A-P-K-T-D-K


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Q-C-P-H-C-H-H-N-G-S-R-V-V-D-S-R-P-T-D-D-G-R-V-I-R-R-R-R-E-C-E-N-C-G-F-R-F-T-T-F-E-R-V-E-A-T-P-L-L-V-I-K-K-N-G-A-R-E-E-F-N-R-E-K-V-L-R-G-I-I-R-S-A-E-K-R-P-V-S-M-E-T-M-T-G-V-V-D-D-V-E-N-K-V-R-S-L-G-E-N-E-I-S-S-Q-V-I-G-E-Y-V-M-E-Q-L-A-D-I-D-E-I-S-Y-I-R-F-A-S-V-Y-R-Q-F-K-D-M-H-V-F-L-N-E-L-Q-D-M-M-E-R-D-K-V-K-L-A-K-P-S-A-K-T-T-H-A-P-K-R-K-K-D


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-T-F-N-G-K-I-N-G-N-G-L-K-I-G-I-A-V-A-R-F-N-A-F-V-T-Q-Q-L-L-T-G-A-Q-E-S-L-V-Q-H-G-V-N-E-T-D-I-D-V-A-W-V-P-G-A-F-E-I-P-L-T-V-Q-K-M-I-T-T-K-R-Y-D-G-V-I-A-L-G-A-V-I-R-G-A-T-A-H-F-D-Y-V-C-S-G-V-T-T-G-I-A-T-V-S-L-A-T-D-T-P-I-M-F-G-V-L-T-T-D-T-I-E-Q-A-M-D-R-A-G-F-K-S-G-N-K-G-A-D-C-A-V-S-L-L-E-T-L-D-V-Q-R-A-I-L-K-A-D-L-A


### FUNCTION Regulates the transcription of the arc operon, involved in arginine catabolism ### SEQUENCE -M-K-K-S-E-R-Q-A-V-I-E-Q-L-I-S-E-Y-P-I-A-T-Q-E-E-L-M-A-K-L-K-A-E-G-I-A-A-T-Q-A-T-I-S-R-D-I-R-E-M-Q-I-V-K-T-P-D-E-H-G-Q-T-R-Y-A-I-F-K-T-T-N-K-N-E-Q-D-R-L-F-E-T-L-H-D-V-V-T-S-I-D-R-V-E-F-M-N-I-I-H-T-L-P-S-N-G-N-L-L-A-A-I-I-D-D-L-N-L-P-E-V-S-G-T-L-A-G-H-D-T-I-F-V-V-S-P-N-T-T-V-A-K-Q-L-Y-E-S-F-A-S-H-I-S-N-E-D


### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid  by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-I-M-D-D-V-K-A-T-V-L-S-I-L-Q-D-L-T-G-E-D-V-S-N-N-M-D-A-N-L-F-D-E-G-I-L-D-S-M-G-S-V-Q-L-L-L-E-L-Q-N-Q-L-G-I-E-V-P-V-S-E-F-E-R-S-E-W-E-T-P-A-K-I-V-A-K-V-A-S-L-Q


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-I-K-E-F-K-E-F-I-A-R-G-N-V-I-D-L-A-V-G-V-I-I-G-S-A-F-T-A-I-V-K-S-L-T-D-N-L-I-N-P-L-I-G-I-F-L-G-K-V-D-L-S-N-L-K-F-S-I-G-D-A-T-F-K-Y-G-S-F-L-N-A-I-I-N-F-F-I-V-A-I-V-V-F-I-L-V-K-I-I-N-K-V-V-K-N-E-P-E-E-P-E-E-E-E-V-D-V-S-A-Q-Y-L-E-E-I-R-D-L-L-K-E-Q-A-K-K


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-A-E-E-R-I-N-A-E-Q-V-Q-H-V-A-S-L-A-K-L-E-F-T-P-D-Q-L-A-M-F-T-P-Q-L-E-K-I-I-G-M-F-E-E-L-S-T-V-D-T-T-G-V-P-V-T-S-R-M-S-D-H-T-N-T-L-R-E-D-V-A-V-K-S-D-E-A-L-R-E-A-L-L-K-N-A-P-E-T-A-N-G-L-I-K-V-P-A-I-I-D-E-S-G-D-G-E


### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-E-I-K-T-T-A-V-A-G-T-L-E-S-S-D-I-Q-I-M-L-M-A-G-D-N-G-I-Q-I-D-L-E-S-D-V-I-K-Q-F-G-A-Q-I-K-H-V-I-T-T-T-L-Q-Q-L-N-I-D-N-V-K-V-R-A-V-D-K-G-A-L-D-C-V-I-K-A-R-T-I-T-A-A-Q-R-A-L-E-T-T-T-P-A-W-E-V-L


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-T-T-Y-M-A-K-P-G-E-I-D-R-K-W-Y-V-V-D-A-T-D-V-P-L-G-R-L-S-T-V-V-A-S-I-L-R-G-K-N-K-P-T-F-T-P-N-V-D-T-G-D-N-V-I-V-I-N-A-S-K-V-A-L-T-G-K-K-A-E-R-K-I-Y-Y-H-H-T-A-Y-A-G-G-L-K-E-R-T-A-G-D-F-L-A-K-E-P-T-K-L-I-E-T-S-V-K-G-M-L-P-H-N-S-L-G-H-K-M-G-L-K-L-H-V-Y-A-G-A-E-H-T-Q-Q-A-Q-K-P-E-V-L-D-I-T-N-L-I


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-T-R-K-T-T-R-R-R-R-V-K-K-N-I-E-S-G-V-A-H-I-H-S-T-F-N-N-T-L-V-M-I-T-D-M-Q-G-N-A-I-A-W-S-S-A-G-S-L-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-A-A-A-K-A-S-M-E-H-G-M-K-T-V-E-V-A-V-K-G-P-G-S-G-R-E-A-A-I-R-A-L-Q-A-T-G-L-E-V-S-A-I-R-D-V-T-P-V-P-H-N-G-S-R-P-P-K-R-R-R-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-E-G-I-D-L-P-R-D-K-R-I-V-I-G-L-T-Y-I-Y-G-I-G-N-T-S-A-Q-K-I-L-A-E-A-G-V-S-E-D-V-R-V-R-D-L-T-P-D-Q-E-D-K-I-R-A-V-V-D-G-Y-K-T-E-G-D-L-R-R-E-V-S-L-N-I-K-L-L-Q-E-I-G-S-Y-R-G-M-R-H-R-R-G-L-P-V-R-G-Q-H-T-K-N-N-A-R-T-R-K-G-K-K-V-S-I-A-G-R-K-K


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-D-V-I-E-I-Q-G-T-I-K-E-T-L-P-N-A-M-F-K-V-E-L-E-N-G-A-E-I-L-A-H-V-S-G-K-I-R-M-H-Y-I-R-I-L-P-G-D-K-V-T-V-E-M-S-P-Y-D-L-T-K-G-R-I-T-Y-R-F-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-T-P-S-E-G-S-R-F-S-R-R-R-I-G-R-G-D-S-S-G-Q-G-K-T-S-G-R-G-Q-K-G-Q-K-A-R-G-K-V-R-V-G-F-E-G-G-Q-M-P-L-Y-R-R-I-P-K-R-G-F-T-N-I-N-R-K-E-Y-A-V-V-N-L-D-G-L-N-R-F-D-D-G-A-E-V-T-P-E-S-L-K-E-A-G-L-V-K-K-S-S-A-V-K-V-L-G-N-G-K-L-N-K-K-L-T-V-K-A-S-K-F-S-A-T-A-V-A-A-I-E-A-A-G-G-K-T-E-V-I


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-T-F-I-D-P-S-K-L-D-L-D-D-N-V-V-A-I-N-R-I-T-K-V-V-K-G-G-R-R-L-R-F-A-A-L-V-I-V-G-D-H-K-G-H-V-G-F-G-T-G-K-A-Q-E-V-P-E-A-I-R-K-A-S-E-A-A-K-K-N-L-I-T-V-P-M-V-G-T-T-I-P-H-E-A-L-G-V-Y-G-G-G-R-I-M-L-K-P-A-V-E-G-S-G-V-A-A-G-G-A-V-R-A-V-M-E-L-A-G-V-D-D-V-T-S-K-R-L-G-S-N-T-P-V-N-V-V-R-A-T-F-E-G-L-K-S-L-K-T-A-E-Q-V-A-A-L-R-G-V-S-A-E-H-L-A-E


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-T-R-Q-R-R-H-A-R-V-R-G-K-I-S-G-T-A-E-R-P-R-L-N-V-Y-R-S-N-K-N-I-Y-A-Q-V-I-D-D-V-E-G-V-T-L-A-S-A-S-T-L-D-S-E-V-K-G-N-N-K-T-E-K-A-A-S-V-G-E-V-V-A-K-R-A-A-E-K-K-I-V-D-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-Q-A-L-A-E-A-A-R-E-N-G-L-K-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-Y-K-V-I-E-L-P-A-G-V-E-V-S-Q-A-G-E-V-V-T-V-K-G-P-K-G-T-L-T-R-N-I-A-S-D-I-T-M-T-V-E-G-N-E-V-K-F-T-R-P-S-D-D-Y-K-M-K-A-L-H-G-T-T-R-A-N-V-N-N-M-V-E-G-V-T-K-G-F-T-K-N-L-Q-L-V-G-V-G-Y-R-A-Q-L-Q-G-K-K-L-V-L-S-V-G-Y-S-H-P-V-E-F-A-T-P-E-N-L-T-V-E-V-P-D-N-T-H-I-N-I-S-G-I-G-K-Q-A-V-G-D-F-A-A-E-V-R-A-V-R-S-P-E-P-Y-K-G-K-G-I-R-Y-V-D-E-Y-V-R-R-K-E-G-K-T-G-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-M-T-D-P-I-A-D-F-L-T-R-I-R-N-A-N-M-V-R-H-D-S-L-E-V-P-A-S-K-I-K-R-N-I-A-E-I-L-K-N-E-G-F-V-R-D-V-E-Y-I-D-D-D-K-Q-G-I-I-R-V-F-L-K-Y-G-K-D-N-E-R-V-I-S-G-L-K-R-I-S-K-P-G-L-R-S-Y-V-K-A-D-A-V-P-K-V-L-N-G-L-G-I-A-I-I-S-T-S-E-G-V-I-T-D-K-E-A-R-A-K-K-L-G-G-E-V-L-A-Y-V-W


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-Q-I-A-K-Q-K-R-G-A-K-F-N-V-Q-N-Y-T-R-C-E-R-C-G-R-P-H-S-V-Y-R-K-F-H-L-C-R-I-C-L-R-D-L-A-H-K-G-Q-I-P-G-M-K-K-A-S-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-E-N-R-L-K-A-Q-Y-E-K-E-I-V-P-A-L-V-D-K-F-N-Y-T-S-V-M-Q-V-P-K-L-A-K-I-V-L-N-M-G-V-G-D-A-V-T-N-A-K-N-L-D-E-A-V-E-E-L-T-L-I-S-G-Q-K-P-L-V-T-R-A-K-K-S-I-A-G-F-R-L-R-E-G-M-A-I-G-A-K-V-D-L-R-G-E-R-M-Y-D-F-L-D-K-L-I-N-V-S-L-P-R-V-R-D-F-H-G-V-S-T-R-S-F-D-G-R-G-N-Y-T-L-G-V-R-E-Q-L-I-F-P-E-I-N-Y-D-N-V-N-R-V-R-G-L-D-I-V-I-V-T-T-A-D-S-D-E-E-S-R-E-L-L-T-Q-F-G-M-P-F-A-K


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-L-I-K-T-G-D-K-V-R-V-I-S-G-K-D-R-G-Q-E-G-T-V-K-K-V-I-S-A-K-N-R-I-V-V-E-G-V-N-K-I-K-K-H-Q-K-P-T-N-V-N-P-Q-G-G-I-V-D-I-E-A-P-I-D-A-S-N-V-M-Y-L-D-P-S-T-N-E-P-T-R-L-G-V-R-R-E-D-G-K-R-V-R-Y-A-K-K-S-G-K-D-L-E-N


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-S-G-A-R-E-I-L-T-I-K-V-L-G-G-S-G-R-K-T-A-N-I-G-D-V-I-V-A-T-V-K-Q-A-T-P-G-G-V-V-K-A-H-D-V-V-K-A-V-I-V-R-T-K-S-G-V-H-R-A-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-R-D-D-K-T-P-Q-G-T-R-I-F-G-P-V-A-R-E-L-R-D-K-D-F-M-R-I-V-S-L-A-P-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-D-T-R-N-S-R-K-V-I-Q-G-R-V-V-S-D-K-M-D-K-T-I-V-V-I-V-E-T-Y-K-N-H-P-V-Y-G-K-R-V-R-Y-S-K-K-F-K-A-H-D-E-K-N-E-A-K-T-G-D-I-V-K-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-I-E-V-V-Q-K-A-V-I-I


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-Y-R-R-V-H-R-G-K-M-R-G-E-A-K-G-G-K-T-V-A-F-G-D-Y-G-L-Q-T-L-E-S-H-W-I-S-N-R-Q-I-E-A-A-R-V-A-M-N-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-E-K-G-V-G-V-R-M-G-N-G-K-G-T-P-A-G-W-V-A-P-V-K-R-N-K-I-M-F-E-V-A-G-V-P-E-E-V-A-R-E-A-L-R-L-A-G-T-K-L-P-V-K-T-K-I-V-K-R-E-E-V-G-G-E-S-D-E-G


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-E-Q-V-T-S-A-R-A-T-A-K-T-V-R-I-A-A-R-K-V-R-L-V-V-D-L-I-R-G-K-S-V-A-E-A-L-A-I-L-K-F-T-P-R-G-A-S-P-V-V-E-K-V-L-L-S-A-V-A-N-A-E-N-N-F-D-L-D-R-E-D-L-V-V-S-E-A-F-V-N-E-G-P-T-L-K-R-F-R-P-R-A-K-G-S-A-S-P-I-N-K-R-T-S-H-I-T-I-T-V-T-E-K


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-G-R-S-L-K-K-G-P-F-A-D-A-H-L-L-K-K-I-D-A-Q-S-D-S-D-K-K-S-V-I-K-T-W-S-R-R-S-T-I-F-P-S-F-I-G-Y-T-I-A-V-Y-D-G-R-K-H-V-P-V-Y-I-Q-D-D-M-V-G-H-K-L-G-E-F-V-P-T-R-T-F-H-G-H-G-T-D-D-K-K-T-K


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-E-A-R-D-V-I-L-R-P-V-V-T-E-S-S-M-A-D-L-D-D-K-R-Y-T-F-D-V-N-V-Q-A-T-K-T-Q-V-K-K-A-I-E-E-I-F-D-V-K-V-V-K-V-N-V-M-N-V-K-G-K-L-K-R-Q-G-R-Y-A-G-Y-T-K-K-R-R-K-A-I-V-T-L-S-S-D-S-N-E-I-K-L-F-N-D-D-Q-Q


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-K-Q-K-I-R-I-R-L-K-A-Y-E-H-R-I-L-D-Q-S-A-D-K-I-V-E-T-A-K-R-T-G-A-T-I-S-G-P-I-P-L-P-T-E-R-T-I-Y-T-V-L-R-S-P-H-K-F-K-D-S-R-E-Q-F-E-M-R-T-H-K-R-L-I-D-I-V-N-P-T-P-K-T-V-D-S-L-M-K-L-D-L-P-S-G-V-D-I-E-I-K-L


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-A-P-A-K-R-E-V-L-A-D-P-M-Y-N-S-K-L-V-T-R-L-I-N-H-L-M-L-D-G-K-R-G-T-A-S-T-I-L-Y-D-A-F-D-Q-I-K-E-Q-T-G-N-D-P-L-E-V-F-E-E-A-M-K-N-V-M-P-V-L-E-V-K-A-R-R-V-G-G-S-N-Y-Q-V-P-I-E-V-R-P-D-R-K-T-T-L-G-L-R-W-I-V-Q-Y-A-R-S-R-G-E-H-T-M-S-D-R-L-A-R-E-I-M-D-A-A-N-N-T-G-A-S-V-K-K-R-E-D-T-H-R-M-A-E-A-N-R-A-F-A-H-Y-R-W


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-I-R-K-G-R-K-S-K-V-S-K-S-N-A-P-A-L-N-F-G-Y-N-S-Y-K-K-V-A-T-N-N-P-A-P-Q-K-R-G-V-A-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-Y-A-R-V-R-L-S-N-L-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-V-I-R-G-A-L-D-T-A-G-V-E-D-R-R-Q-S-R-S-K-Y-G-T-K-K-P-K-K


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-Q-H-G-K-H-P-D-T-A-L-A-Q-N-R-K-A-R-H-D-Y-A-V-E-E-T-Y-E-A-G-I-A-L-T-G-T-E-I-K-S-V-R-D-R-R-V-N-L-K-D-G-F-V-Q-V-R-N-G-E-A-W-M-Q-N-V-H-I-S-P-F-K-E-G-N-R-Y-N-V-D-P-L-R-S-R-K-L-L-L-H-K-K-E-I-S-K-L-G-A-A-T-M-T-K-G-V-T-I-I-P-L-K-M-Y-L-K-H-G-F-A-K-V-L-I-G-V-A-H-G-K-R-E-Y-D-K-R-Q-D-I-K-K-R-E-Q-Q-R-Q-I-D-R-V-M-K-H-Y


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-Y-P-V-P-T-V-I-E-Q-S-S-R-G-E-R-A-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-S-G-P-I-E-D-N-M-A-N-A-I-I-A-Q-L-L-F-L-D-A-Q-D-S-G-K-D-I-Y-L-Y-I-N-S-P-G-G-V-V-T-A-G-L-A-I-Y-D-T-M-N-F-I-K-S-D-V-Q-T-I-V-M-G-M-A-A-S-M-A-S-V-L-A-S-S-G-T-K-G-K-R-F-A-L-P-N-S-E-I-L-I-H-Q-P-S-G-G-A-Q-G-Q-Q-T-E-I-E-I-V-A-E-E-I-L-K-T-R-K-K-I-N-Q-I-L-A-D-N-S-G-Q-S-V-E-K-L-N-H-D-T-E-R-D-N-Y-L-S-A-Q-E-A-K-D-Y-G-L-I-D-D-I-M-E-N-N-K-L-K


### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-A-K-V-E-S-F-T-L-D-H-T-K-V-L-A-P-Y-V-R-K-I-T-V-E-N-G-P-K-G-D-A-I-T-N-F-D-L-R-L-V-Q-P-N-K-T-A-I-D-T-A-G-L-H-T-I-E-H-M-L-A-G-L-L-R-D-R-M-D-G-V-I-D-C-S-P-F-G-C-R-T-G-F-H-L-I-T-W-G-E-H-D-T-V-E-V-A-K-A-L-K-S-S-L-E-F-I-A-G-P-A-K-W-E-D-V-Q-G-T-T-I-D-S-C-G-N-Y-K-D-H-S-L-F-S-A-K-E-W-A-K-L-I-L-S-Q-G-I-S-S-D-P-F-V-R-K-V-V-E


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-I-L-Q-Q-Q-E-E-E-E-Q-T-I-G-G-I-V-I-A-N-N-A-K-E-K-P-Q-S-G-K-V-V-A-V-N-D-G-R-V-L-D-N-G-T-K-V-D-P-S-V-K-V-G-D-Q-V-L-F-D-K-Y-A-G-T-E-V-K-Y-Q-G-A-K-Y-L-V-L-H-E-K-D-I-V-A-I-E-D


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Q-Y-P-E-P-I-A-K-L-I-D-S-Y-M-K-L-P-G-I-G-G-K-T-A-T-R-L-A-F-Y-T-I-D-M-N-G-D-D-V-T-E-F-A-K-S-L-I-A-A-K-R-D-L-H-F-C-S-I-C-G-N-I-T-E-D-D-P-C-V-I-C-K-D-K-S-R-D-Q-S-T-V-L-V-V-E-E-A-K-D-V-M-A-M-E-K-I-K-E-Y-N-G-L-Y-H-V-L-H-G-V-L-S-P-I-D-G-K-G-P-E-D-I-N-I-A-S-L-L-K-R-L-Q-Q-N-E-A-I-K-E-V-I-I-A-T-N-A-T-P-E-G-E-A-T-A-M-Y-I-S-R-L-V-K-P-A-G-I-K-V-T-R-L-A-H-G-L-S-V-G-S-D-I-Q-Y-A-D-E-M-T-L-F-K-A-V-E-G-R-Q-E-M


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-R-G-M-G-N-M-Q-S-M-M-K-Q-M-K-K-M-Q-A-Q-M-T-A-E-Q-A-A-L-N-E-Q-T-F-T-G-A-A-P-D-D-M-V-K-V-T-F-T-G-D-K-K-M-K-D-I-T-I-N-P-D-A-V-D-P-D-D-V-D-M-L-Q-D-L-V-V-A-A-V-N-D-A-L-T-K-V-D-E-Q-T-Q-S-T-M-G-K-Y-T-K-G-L-Q


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-F-D-K-D-A-I-I-D-S-L-K-E-A-S-I-S-D-L-N-D-L-V-K-A-I-E-E-E-F-D-V-S-A-S-A-P-V-A-V-A-G-A-A-G-G-D-A-A-A-A-K-D-S-Y-D-V-E-L-T-E-S-G-D-Q-K-V-K-A-I-K-A-V-R-D-I-T-G-L-G-L-K-D-A-K-G-L-V-D-N-V-P-S-I-I-K-E-G-V-S-E-D-E-A-N-D-M-K-A-K-L-E-E-V-G-G-V-V-T-L-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-K-E-T-I-A-V-K-A-Q-E-V-E-E-V-A-E-Q-L-K-S-S-V-S-A-I-V-V-D-Y-R-G-L-T-V-E-Q-V-T-D-L-R-K-Q-L-R-E-A-G-V-K-M-R-V-I-K-N-K-I-M-V-R-A-A-D-K-A-G-F-E-D-L-K-P-V-F-A-G-P-T-A-V-A-F-S-E-E-D-P-V-A-P-A-K-I-L-A-N-F-A-K-T-A-D-A-L-Q-L-K-G-G-V-I-E-G-K-V-A-D-L-E-T-V-Q-E-Y-A-T-M-P-S-R-E-E-L-L-A-T-I-A-N-L-L-Q-A-P-V-R-N-V-A-Y-A-V-K-A-V-A-E-K-G-D-E-D-A-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-A-N-V-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-I-N-I-M-G-F-T-K-D-F-N-A-R-T-A-D-Q-A-G-M-I-I-P-V-V-I-T-V-Y-E-D-R-S-F-D-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-E-S-G-S-G-E-P-N-T-K-K-V-A-T-V-T-K-D-Q-V-K-Q-I-A-E-T-K-M-Q-D-L-N-A-A-D-V-E-A-A-M-R-M-I-E-G-T-A-R-S-M-G-F-T-V-E-G


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-M-I-V-G-L-G-N-I-G-R-Q-Y-A-Q-T-R-H-N-V-G-F-M-I-V-D-E-L-A-S-K-L-N-V-T-F-Q-T-S-K-F-E-A-Q-V-A-T-A-F-Q-D-G-E-K-I-L-L-V-K-P-A-T-Y-M-N-D-S-G-R-A-V-G-P-L-M-S-Y-Y-N-V-D-P-A-D-L-L-V-I-H-D-D-L-D-L-P-L-G-K-V-R-L-K-Q-K-G-S-A-G-G-H-N-G-I-K-S-I-I-S-H-V-G-D-Q-H-F-K-R-V-K-V-G-I-D-H-P-Q-K-M-S-V-V-D-Y-V-L-G-K-F-T-P-A-E-V-A-K-F-D-D-A-K-I-T-A-L-A-A-V-E-A-W-L-A-N-D-D-F-T-A-V-M-N-Q-Y-N


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-Y-G-T-G-I-D-L-T-E-L-S-R-I-E-A-I-L-A-K-G-L-R-L-P-E-K-I-L-T-P-A-E-L-A-V-F-S-R-Y-P-V-K-R-Q-I-E-F-M-A-G-R-F-S-A-K-E-A-Y-S-K-A-Y-G-T-G-I-G-A-A-V-G-F-Q-D-I-E-I-L-D-N-A-Q-G-K-P-E-V-T-R-H-P-F-D-G-P-A-W-I-S-I-S-H-T-D-T-L-V-M-T-Q-V-I-L-E-R-G-N-L


### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-E-L-K-Q-F-D-G-Q-K-K-S-E-L-S-L-I-E-V-A-H-A-I-L-S-Q-H-G-D-V-M-A-F-A-D-L-T-N-A-V-Q-S-Y-L-G-K-S-D-E-E-I-R-E-R-L-S-Q-F-Y-T-D-L-N-I-D-G-S-F-I-S-L-G-D-N-M-W-G-L-R-A-W-Y-P-F-E-S-I-D-E-A-V-I-H-T-D-D-D-E-D-E-D-R-P-K-R-K-K-V-N-A-F-L-A-D-A-G-D-D-D-D-V-I-D-Y-D-D-D-D-P-E-D-D-D-N-Y-D-D-D-D-D-Q-D-D-D-T-D-D-S-A-S-S-K-Y-D-E-L-A-G-V-D-D-T-D-D-D-V-A-D-E-T-L-P-D-G-I-E-G-Q-L-S-E-L-N-D-D-D-D-D-D-D-Y-D-D-E-D-D-E-S-K


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-E-P-T-F-N-K-M-T-A-A-G-Y-H-A-I-E-Q-E-I-E-D-L-K-Q-Q-R-P-E-R-I-R-I-L-A-A-A-A-A-L-G-D-R-S-E-N-A-E-Y-S-S-A-K-R-D-L-G-R-L-E-S-R-L-R-Y-L-N-K-Q-L-Q-Y-A-Q-I-V-Q-P-A-D-N-D-Q-L-D-I-G-K-F-V-T-I-E-F-L-D-D-H-D-Q-I-T-Y-Q-L-V-G-K-Q-E-A-N-L-E-Q-Q-K-I-S-F-T-S-P-I-G-Q-A-L-A-N-H-T-V-D-D-V-V-T-V-N-A-P-N-G-A-Y-Q-V-K-V-I-A-V-K-R-A


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-K-K-I-I-A-I-T-G-F-A-M-L-G-G-G-L-R-E-G-L-S-L-L-V-T-W-P-Q-H-F-W-I-T-C-L-I-N-I-V-G-A-F-V-L-S-L-I-T-N-L-L-P-A-R-L-P-V-S-E-D-I-V-I-G-M-S-V-G-F-V-G-S-F-T-T-F-S-T-F-T-F-E-T-L-Q-S-F-Q-S-G-H-S-V-L-A-L-S-Y-V-A-A-S-L-G-L-G-L-L-A-G-L-A-G-N-F-L-S-T-Y-W-L-P-K-E-E-F


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-L-V-L-V-G-L-A-G-A-G-A-A-V-G-A-L-S-R-Y-G-I-M-R-L-A-L-P-L-N-R-W-P-L-P-I-A-T-L-F-I-N-L-T-G-A-L-L-L-G-W-I-L-T-S-S-L-P-P-N-W-Q-I-F-L-G-T-G-I-M-G-G-Y-T-T-F-S-T-M-I-N-E-L-V-L-L-G-R-N-H-H-Q-R-V-A-W-E-Y-F-G-L-S-L-V-G-G-L-V-M-V-Y-L-G-T-L-I


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-N-I-K-I-I-C-V-G-K-L-K-E-K-Y-F-K-Q-G-I-A-E-Y-A-K-R-M-S-K-F-A-K-F-Q-I-V-E-V-P-D-E-K-A-P-E-S-L-S-N-A-E-M-E-N-V-K-A-K-E-G-Q-R-I-L-E-K-I-K-D-R-D-Y-V-Y-A-L-A-I-L-G-K-E-R-S-S-E-E-F-A-A-E-I-D-K-L-T-T-Y-G-H-S-D-I-D-F-V-I-G-G-S-L-G-L-S-P-E-V-L-K-R-A-D-T-Q-I-S-F-G-R-F-T-L-P-H-Q-L-M-R-L-V-L-S-E-Q-V-Y-R-A-F-M-I-N-V-G-S-P-Y-H-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-Q-V-I-F-L-N-D-V-R-G-K-G-K-R-G-Q-I-K-N-V-P-D-G-Y-A-Q-N-F-L-I-K-K-G-L-A-K-E-A-T-K-A-A-I-N-T-L-K-A-E-Q-K-S-E-A-A-R-A-A-E-E-L-A-E-A-K-Q-V-K-T-V-L-E-A-D-E-T-V-V-E-L-K-A-K-A-G-T-D-G-R-L-F-G-S-I-P-S-K-Q-I-A-T-A-L-A-D-Q-Y-Q-V-K-L-D-K-R-K-I-E-L-P-E-P-I-R-V-L-G-Y-T-N-V-P-V-K-L-H-P-E-V-T-A-K-I-R-V-H-V-V-E-K


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Q-Q-R-R-G-G-R-R-R-R-K-V-D-F-I-A-A-N-H-I-E-Y-I-D-Y-K-D-T-D-L-L-R-R-F-I-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-N-Q-R-S-L-T-I-A-I-K-R-A-R-I-M-G-L-L-A-F-V-S-E-D


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-R-T-I-L-V-G-R-L-T-R-D-P-E-L-R-Y-T-N-G-G-A-A-V-A-T-F-T-I-A-V-N-R-Q-F-T-N-Q-N-G-E-R-E-A-D-F-I-S-C-V-I-W-R-K-A-A-E-N-F-A-N-F-T-H-K-G-S-L-V-G-I-D-G-R-I-Q-T-R-N-Y-E-N-Q-Q-G-V-R-V-Y-V-T-E-V-V-V-E-N-F-S-L-L-E-S-R-A-E-S-E-R-H-Q-A-A-N-G-G-S-G-N-N-N-Y-N-N-G-N-S-N-Y-N-N-N-N-N-G-Y-S-N-Q-G-Q-N-A-A-P-Q-Q-S-S-A-N-N-N-N-P-F-G-N-G-N-T-G-N-A-S-S-A-A-P-S-S-S-A-N-N-N-N-Q-A-D-P-F-A-N-N-G-D-Q-I-D-I-S-D-D-D-L-P-F


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-S-E-S-K-K-Y-E-I-T-Y-I-V-R-P-D-I-D-D-A-A-K-T-A-L-V-D-R-F-D-K-I-L-T-D-N-G-A-Q-V-I-D-S-K-D-W-S-K-R-R-F-A-Y-E-I-G-G-F-N-E-G-T-Y-H-I-V-N-L-T-A-T-D-D-A-A-L-N-E-F-D-R-L-S-K-I-N-D-D-I-L-R-H-M-I-V-K-R-E-D


### FUNCTION Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 ### SEQUENCE -M-R-K-Y-F-L-G-E-E-F-T-K-Q-D-L-K-Q-M-N-P-L-V-L-A-Y-I-G-D-A-V-Y-E-I-F-I-R-T-Y-I-I-S-K-N-K-D-T-C-V-N-K-L-H-K-K-T-I-Q-F-V-K-A-D-A-Q-S-Y-F-I-R-E-I-Q-K-Y-L-N-E-E-E-I-K-V-F-K-R-G-R-N-T-K-S-N-T-S-A-K-N-A-S-I-Q-D-Y-R-M-A-T-G-F-E-T-V-I-G-Y-L-Y-L-L-N-E-D-E-R-L-E-E-I-M-K-L-V-I-N-L-Y-E-E-S-S-Q-N-E-G-E-N-H-G-S-K-S


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-T-G-M-I-K-L-Q-L-A-A-G-K-A-S-P-A-P-P-V-G-P-A-L-G-Q-H-G-V-N-I-M-A-F-C-K-E-F-N-E-K-T-A-K-Q-A-G-L-I-I-P-V-V-I-T-V-Y-Q-D-R-S-F-S-F-I-L-K-T-P-P-A-A-V-L-I-K-K-A-V-G-I-E-S-G-S-G-V-P-N-K-T-K-V-A-K-I-T-K-E-Q-L-K-E-I-A-E-M-K-M-P-D-L-N-A-G-S-V-E-A-A-M-R-M-V-A-G-T-A-R-S-M-G-V-T-V-E-E


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-R-R-W-H-T-V-S-K-N-R-Q-L-K-E-A-K-V-A-E-I-K-E-K-M-E-K-A-E-C-I-V-L-A-D-Y-Q-G-L-T-V-E-E-A-T-E-L-R-K-K-M-R-E-E-G-V-E-Y-K-V-F-K-N-T-L-S-I-L-A-A-K-E-L-G-Y-E-G-I-T-D-L-F-Q-G-P-I-S-I-A-F-G-Y-E-D-P-T-A-P-A-R-I-L-N-D-F-A-K-D-H-K-K-L-E-L-K-G-G-M-V-Q-G-E-V-Y-D-E-D-K-I-K-A-L-A-A-I-P-P-R-D-V-L-I-A-K-L-L-G-S-F-K-A-P-V-S-N-F-A-Y-L-I-N-A-I-K-E-K-K-E-S-E-E-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-P-R-K-G-Y-I-G-K-R-D-V-L-P-D-P-M-Y-N-S-K-V-L-T-K-L-I-N-S-L-M-Y-D-G-K-K-G-L-A-Q-K-I-C-Y-D-A-F-D-V-I-Q-N-K-T-G-K-E-P-M-E-V-F-E-E-A-M-N-N-V-M-P-L-L-E-V-K-A-R-R-I-G-G-A-T-Y-Q-V-P-L-E-V-R-P-E-R-R-Q-T-L-G-I-R-W-I-L-I-A-A-R-K-R-G-E-K-Y-M-S-E-R-L-A-G-E-L-M-D-A-A-N-N-L-G-A-A-V-K-K-R-E-E-T-H-K-M-A-E-A-N-K-A-F-A-H-Y-R-Y


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-I-A-K-Y-V-R-M-S-P-R-K-V-G-V-V-L-D-L-V-R-G-K-D-V-N-E-A-F-A-I-L-N-Y-T-P-R-E-A-A-V-V-I-N-K-V-L-K-S-A-V-A-N-A-E-N-N-L-E-L-D-P-S-R-L-Y-V-A-E-A-Y-A-C-Q-G-P-T-L-K-R-Y-Q-P-H-A-Q-G-R-A-F-R-I-N-K-R-T-S-H-V-T-L-V-V-K-E-R-E


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-M-P-K-R-V-K-H-R-K-V-Q-R-G-R-M-K-G-K-A-T-R-G-N-F-I-A-Y-G-D-Y-G-I-Q-A-T-E-C-G-W-I-T-S-N-Q-I-E-S-A-R-I-A-I-N-R-Y-I-R-R-G-G-K-L-W-I-K-I-F-P-D-K-P-V-T-Q-K-P-A-E-T-R-M-G-S-G-K-G-T-P-E-Y-W-V-A-V-V-K-P-G-R-V-L-F-E-L-T-G-V-D-E-E-T-A-R-E-A-M-R-L-A-A-H-K-L-P-V-K-T-K-F-V-K-K-S-D-F-E-E-V-G-G-E-I-N-E-G


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-Q-T-T-L-K-V-A-D-N-S-G-A-R-G-I-M-C-I-K-V-L-G-G-S-N-R-R-Y-A-N-I-G-D-I-I-V-A-S-V-K-S-A-T-P-G-G-V-V-K-K-G-E-V-V-K-A-V-V-V-R-S-K-K-G-V-R-R-A-D-G-S-Y-I-K-F-D-E-N-A-A-V-I-I-K-D-D-K-Q-P-K-G-T-R-I-F-G-P-V-A-R-E-L-R-D-K-E-F-N-K-I-L-S-L-A-P-E-V-L


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-Q-N-K-V-H-V-R-K-Q-D-T-V-M-V-I-S-G-K-D-K-G-K-I-G-E-V-L-R-V-L-P-K-S-G-K-V-V-V-K-D-V-N-V-V-T-K-H-Q-K-P-S-R-E-N-M-Q-G-G-I-I-H-V-E-A-P-I-Y-S-S-K-V-M-L-Y-C-T-K-C-K-S-V-T-R-I-N-H-K-I-L-D-D-G-T-K-V-R-V-C-K-K-C-G-E-T-F


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-V-P-R-L-Q-E-K-Y-E-K-E-V-I-P-A-L-I-E-K-F-G-Y-K-N-I-M-E-V-P-K-L-E-K-I-V-I-N-M-G-V-G-E-A-K-E-N-Q-K-M-L-E-S-A-V-S-D-L-S-I-I-A-G-Q-K-P-I-V-T-K-A-K-K-S-V-A-N-F-K-I-R-E-N-M-P-I-G-C-K-V-T-L-R-K-V-K-M-Y-E-F-A-D-K-L-M-N-V-A-L-P-R-V-R-D-F-R-G-V-S-S-K-S-F-D-G-R-G-N-Y-S-L-G-V-K-E-Q-L-M-F-P-E-I-E-Y-D-K-V-D-K-V-R-G-M-D-I-I-F-V-T-T-A-K-T-D-E-E-A-R-E-L-L-R-F-L-G-M-P-F-A-H


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-L-L-T-R-V-R-N-A-N-I-A-R-H-E-A-V-E-I-P-A-S-N-I-K-K-A-I-A-N-I-M-L-Q-E-G-Y-I-T-D-L-E-E-Y-N-D-G-A-V-P-M-L-K-I-T-M-K-Y-G-Q-N-K-E-R-V-I-T-G-L-K-R-I-S-K-P-G-L-R-V-Y-C-R-K-D-E-V-P-K-V-L-N-G-L-G-T-A-V-I-S-T-S-K-G-I-L-P-D-K-E-A-R-K-L-S-I-G-G-E-V-L-C-Y-I-W


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-R-L-P-I-A-I-P-N-G-V-T-V-T-V-S-P-E-N-V-V-T-V-K-G-P-K-G-E-L-T-K-T-M-H-P-N-I-D-I-A-I-E-E-N-S-V-I-V-T-R-K-N-D-E-K-Q-N-R-S-L-H-G-L-T-R-S-L-V-N-N-M-V-V-G-V-T-E-G-Y-E-K-K-L-E-L-V-G-V-G-Y-R-A-Q-L-Q-G-K-K-L-V-L-N-L-G-F-S-H-P-V-E-I-E-A-K-E-G-V-E-F-Q-L-D-G-T-N-K-I-T-V-K-G-I-D-K-E-L-V-G-A-V-A-S-D-I-R-S-W-R-K-P-E-P-Y-K-G-K-G-I-K-Y-E-N-E-A-I-R-R-K-E-G-K-T-G-K-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-F-K-K-Q-S-R-Q-K-G-R-E-K-R-H-L-R-I-R-K-N-I-F-G-T-P-E-M-P-R-L-S-V-Y-R-S-E-K-N-I-Y-A-Q-I-I-D-D-L-N-G-V-T-L-V-A-A-S-S-L-D-K-E-F-D-A-K-G-S-N-K-D-G-A-K-L-V-G-E-L-V-A-K-R-A-I-E-K-G-V-T-K-V-V-F-D-R-G-G-Y-I-Y-H-G-R-V-Q-E-L-A-E-G-A-R-E-A-G-L-Q-F


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-R-P-A-E-G-S-R-K-S-P-K-R-V-G-R-G-T-G-S-G-L-G-K-T-S-A-R-G-E-N-G-Q-N-S-R-S-G-G-G-V-R-P-G-F-E-G-G-Q-M-P-L-Y-R-R-L-P-K-R-G-F-T-N-I-F-A-K-K-Y-T-A-I-N-I-D-R-L-N-I-F-E-D-D-T-V-V-T-P-E-L-L-I-E-K-G-V-I-S-K-V-Y-D-G-V-K-I-L-G-N-G-E-L-D-K-K-L-I-V-K-A-T-K-F-S-K-A-A-A-E-K-I-E-A-A-G-G-K-V-E-V-I


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-D-L-P-R-E-K-R-V-E-V-G-L-T-Y-I-F-G-I-G-T-S-S-A-K-K-I-L-K-E-T-G-V-N-P-D-I-R-I-K-D-L-S-E-E-E-V-N-L-L-R-D-Y-I-N-Q-N-L-K-V-E-G-D-L-R-R-D-V-A-L-D-I-K-R-L-K-E-I-G-S-Y-R-G-I-R-H-R-R-G-L-P-V-R-G-Q-K-T-K-T-N-A-R-T-R-K-G-P-K-K-L-V-V-S-R-K-K-K


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-A-V-S-K-T-K-R-T-R-R-R-K-E-R-K-N-I-E-R-G-C-A-H-I-K-S-T-F-N-N-S-I-V-T-L-T-D-T-A-G-N-A-L-S-W-A-S-A-G-G-L-G-F-R-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-T-A-A-K-A-A-M-E-H-G-L-K-S-V-E-V-Y-V-K-G-P-G-S-G-R-E-A-A-I-R-S-L-Q-A-A-G-L-E-V-T-L-I-K-D-V-T-P-I-P-H-N-G-C-R-P-P-K-R-R-R-V


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-S-Y-I-A-K-P-E-E-V-Q-R-K-W-Y-V-V-D-A-E-G-K-P-L-G-R-V-A-S-Q-V-A-L-I-L-R-G-K-N-K-P-T-Y-T-P-H-V-D-T-G-D-Y-V-V-I-I-N-A-E-K-V-V-L-T-G-K-K-L-D-Q-K-M-L-R-H-H-S-L-Y-P-G-G-L-K-E-V-P-Y-K-E-A-L-A-K-K-P-E-F-V-F-E-E-A-V-R-R-M-L-P-K-G-P-L-G-R-K-M-L-K-K-L-K-V-Y-R-G-S-E-H-N-N-E-A-Q-N-P-E-V-L-E-L-R-Y


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-L-G-I-G-I-D-I-I-E-I-I-R-I-K-N-A-I-E-R-N-S-K-F-M-K-R-V-F-T-E-K-E-I-K-Y-F-E-K-I-N-F-R-H-E-S-I-A-G-R-F-A-A-K-E-A-I-V-K-A-L-G-T-G-F-R-N-M-K-I-T-D-I-E-V-I-N-D-K-V-G-K-P-L-V-E-L-K-G-G-A-L-E-K-I-K-V-Y-K-D-V-K-I-H-L-S-I-S-H-N-R-D-N-A-I-A-Y-S-I-I-E-G-E-C-I


### FUNCTION Involved in allosteric regulation of aspartate carbamoyltransferase ### SEQUENCE -M-L-T-I-T-S-I-K-D-G-I-V-I-D-H-I-K-S-G-Y-G-I-K-I-F-N-Y-L-N-L-K-N-V-E-Y-S-V-A-L-I-M-N-V-F-S-S-K-L-G-K-K-D-I-I-K-I-A-N-K-E-I-D-I-D-F-T-V-L-G-L-I-D-P-T-I-T-I-N-I-I-E-D-E-K-I-K-E-K-L-N-L-E-L-P-K-K-V-E-D-V-I-R-C-K-N-P-R-C-I-T-S-I-E-K-Y-I-P-H-V-F-Y-L-I-D-K-E-K-V-E-Y-K-C-K-Y-C-D-E-I-Y-K-V-V-E-E


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-V-T-I-E-D-K-I-N-L-F-S-K-I-I-Y-G-E-V-D-D-K-I-N-S-E-L-D-E-L-E-N-V-E-K-D-T-I-E-K-E-E-R-E-V-K-K-Y-R-N-K-N-M-Q-S-V-E-K-K-I-K-S-K-F-E-K-E-V-F-K-L-K-L-E-E-Q-Q-Q-L-L-N-L-K-E-N-M-I-N-E-T-L-E-S-L-K-E-R-I-I-D-F-T-K-S-D-E-Y-I-N-Y-I-K-S-H-L-D-N-T-L-K-D-I-E-N-K-E-G-I-I-I-Y-F-N-K-K-D-L-E-K-F-K-K-V-I-N-K-D-N-V-E-V-S-N-E-S-K-D-I-I-G-G-Y-I-I-Q-D-K-N-N-K-F-R-V-D-C-S-L-E-I-S-I-E-E-C-K-E-K-I-G-I-S-I-T-E-L-F-M


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-N-I-I-K-K-G-F-L-M-N-E-E-I-R-E-K-E-V-R-V-I-A-E-D-G-E-Q-L-G-V-I-P-T-S-E-A-L-K-R-A-E-E-K-E-L-D-L-V-M-I-A-P-T-G-K-P-P-V-C-K-I-M-N-Y-G-K-F-I-Y-E-Q-T-K-K-D-K-E-A-K-K-K-Q-K-V-I-N-V-K-E-I-R-L-S-A-T-I-E-E-H-D-I-G-I-K-A-N-N-A-R-K-F-L-K-A-E-D-K-V-K-V-T-V-R-F-R-G-R-E-M-E-H-S-N-V-V-G-N-K-I-L-K-T-F-L-S-K-V-E-D-V-C-V-V-E-K-P-A-R-L-E-G-K-N-M-T-M-V-L-A-P-R-K


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-A-M-N-A-R-K-K-H-K-K-I-L-K-L-S-K-G-Y-F-G-G-K-S-R-L-F-K-T-A-N-E-S-V-I-R-A-L-R-N-A-Y-T-G-R-K-L-K-K-R-D-Y-R-K-L-W-I-A-R-I-N-A-A-T-R-A-N-G-L-S-Y-S-R-F-M-N-G-L-K-L-A-G-I-D-M-N-R-K-M-L-S-E-I-A-I-N-D-P-K-A-F-S-E-L-V-E-A-A-K-K-Q-L-N-A


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-D-Y-I-K-G-I-Y-K-G-M-H-K-D-Y-I-T-V-E-N-N-G-I-G-Y-K-I-F-T-S-G-N-T-L-Y-E-T-P-E-K-D-E-E-I-K-L-Y-I-Q-Q-I-P-R-D-D-S-I-N-L-Y-G-F-F-T-E-E-E-R-D-M-F-N-L-L-M-T-I-S-G-V-G-A-K-S-S-L-S-L-L-S-V-T-S-I-N-K-L-K-Y-S-I-V-T-E-D-T-T-L-L-T-R-A-P-G-I-G-R-K-T-A-E-R-I-I-L-E-L-K-D-K-F-K-N-D-D-I-I-S-D-I-D-D-L-D-S-I-S-N-F-Q-L-H-S-A-E-A-L-E-A-L-M-S-L-G-Y-S-Q-K-E-S-E-K-A-L-K-N-V-D-K-E-N-S-L-E-D-I-I-K-A-C-L-K-Y-L-M-G


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-K-D-K-I-R-V-I-Q-G-F-P-K-E-G-I-S-F-K-D-V-T-T-I-L-Q-E-K-E-A-F-K-Y-T-I-D-T-L-V-E-E-L-K-D-K-N-V-D-V-V-V-G-P-E-A-R-G-F-L-F-G-A-P-L-A-Y-A-L-G-A-G-F-V-P-V-R-K-K-G-K-L-P-S-T-T-I-S-S-K-Y-E-L-E-Y-G-S-D-E-L-E-M-H-K-D-S-I-K-P-G-Q-R-V-V-I-A-D-D-L-L-A-T-G-G-T-I-C-S-V-I-E-M-I-E-S-L-G-G-E-I-V-S-I-N-F-L-I-E-L-T-D-L-K-G-R-E-K-L-G-K-Y-D-I-S-S-L-V-Q-Y-D-I


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-V-V-T-G-G-K-Q-Y-K-V-T-E-G-D-V-L-F-V-E-K-L-D-A-E-V-D-A-A-I-E-L-D-N-V-L-A-I-S-K-D-N-G-E-F-V-V-G-K-P-V-V-E-G-A-K-V-T-A-K-V-L-K-Q-G-K-A-K-K-V-V-V-F-K-Y-K-P-K-K-H-Y-R-K-K-Q-G-H-R-Q-P-Y-T-K-I-Q-I-E-K-I-N-A


### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-K-K-K-A-I-F-G-G-T-F-D-P-I-H-N-G-H-L-H-I-A-Y-K-A-L-N-R-L-K-L-D-K-I-I-F-I-P-S-G-N-P-P-H-K-H-K-E-C-I-T-D-K-N-I-R-Y-N-M-V-K-Y-A-I-E-Q-E-D-K-F-E-I-S-D-Y-E-V-K-K-K-G-K-S-Y-T-Y-E-T-I-E-H-F-R-K-Y-H-P-N-I-D-L-Y-F-I-A-G-A-D-C-L-M-D-I-H-K-W-K-N-I-D-S-M-M-E-K-A-K-L-V-V-F-S-R-P-G-F-S-M-D-T-I-L-F-Q-K-K-Q-V-E-E-K-F-K-K-D-I-I-F-L-D-I-P-L-L-D-V-S-S-T-E-I-R-E-K-I-K-K-G-E-D-I-K-D-L-I-P-E-K-T-Y-N-I-I-K-K-Y-G-L-Y-R


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-K-W-R-H-D-Y-M-A-E-K-K-V-E-D-L-E-M-D-L-N-E-E-E-L-E-E-S-E-V-N-E-D-K-E-F-E-E-L-D-K-S-E-E-E-N-E-V-E-E-L-I-S-T-L-K-D-E-N-E-K-L-N-N-E-M-E-A-L-K-D-R-L-L-R-T-T-G-E-Y-D-N-Y-R-K-R-T-D-R-E-K-E-G-L-Y-A-S-A-C-E-D-V-L-K-E-I-L-P-V-L-D-N-L-E-R-A-I-L-A-K-G-D-I-E-D-L-K-K-G-V-D-M-T-L-K-Q-F-K-D-S-F-K-N-L-G-V-E-E-I-S-T-E-N-G-F-D-P-N-L-H-D-A-V-M-H-V-E-D-S-Q-Y-G-E-K-E-V-V-E-V-F-L-K-G-Y-K-K-G-D-K-I-I-R-H-S-M-V-K-V-A-N


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-Y-I-D-N-R-Q-N-K-I-K-A-Q-E-D-L-D-K-L-I-N-E-I-I-D-Y-A-L-K-K-E-E-V-D-I-G-Y-E-I-S-V-I-Y-V-D-N-E-I-I-K-E-I-N-N-D-T-R-G-I-N-K-E-T-D-V-L-S-F-P-M-L-E-Y-P-K-G-R-V-F-S-E-S-Y-R-E-Y-S-F-G-V-E-Y-L-N-E-G-N-L-V-L-G-D-I-V-L-S-L-E-K-A-L-E-Q-S-K-E-Y-N-H-S-F-L-R-E-V-C-Y-L-V-V-H-S-V-L-H-L-L-G-Y-D-H-I-D-E-E-E-K-V-I-M-R-K-K-E-E-E-I-L-E-S-F-N-I-S-R-G


### FUNCTION Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors , playing an important role in chemotaxis ### SEQUENCE -M-H-T-M-E-V-K-E-Y-R-V-G-I-A-D-L-N-V-A-K-S-P-D-R-I-I-T-V-G-L-G-S-C-I-G-I-A-L-Y-D-R-I-N-G-V-G-G-L-L-H-I-M-L-P-D-S-T-Q-F-K-N-V-S-N-P-L-K-F-P-D-L-G-I-I-I-M-T-D-K-M-K-E-K-G-A-N-I-R-N-I-K-A-K-I-S-G-G-A-S-M-F-N-F-S-D-K-S-M-V-M-D-I-G-R-R-N-I-E-A-V-R-K-K-L-K-E-L-S-I-P-I-V-A-E-E-V-G-G-N-K-G-R-T-M-T-L-D-T-S-N-G-I-V-Q-I-K-T-V-G-V-G-M-K-E-I


### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-K-L-N-T-K-H-H-G-T-I-D-Y-E-E-K-D-I-I-N-F-K-R-G-L-P-G-F-E-H-L-K-K-F-I-V-Y-S-I-E-E-N-N-I-F-S-V-L-Q-S-L-E-E-E-N-I-G-I-P-V-L-S-P-F-T-I-C-S-D-Y-E-V-K-L-T-E-E-Q-I-K-N-L-K-I-K-S-E-E-E-V-W-V-L-N-T-V-T-I-N-S-D-Y-K-E-I-T-T-N-L-R-A-P-I-I-I-N-I-K-E-R-I-G-E-Q-I-I-L-K-N-E-E-Y-K-I-K-Y-P-I-F-Q-E-E-N-K-C


### FUNCTION Involved in the viral transport within, and between cells ### SEQUENCE -M-D-S-F-G-R-A-P-P-L-W-P-Q-S-A-L-P-R-V-P-G-A-A-P-S-S-S-G-L-P-W-S-R-V-G-E-I-A-I-F-T-F-V-A-V-L-A-L-Y-L-L-W-S-W-V-G-R-D-L-L-L-V-L-K-A-R-R-G-G-T-T-E-E-L-T-F-G-P-R-E-R-H-S-L-P-A-V-A-V-A-R-V-E-N-P-P-C-P-S-G-S-V-E-A-R-P-F-T-G


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-G-K-V-L-N-K-V-M-G-F-L-G-L-E-D-E-Y-E-Y-E-E-Y-Y-E-D-T-D-E-L-E-N-S-N-E-S-A-E-F-E-P-I-I-H-S-N-K-K-Q-G-K-V-V-S-I-H-S-T-S-T-P-K-V-S-I-V-K-P-K-T-Y-D-E-V-V-D-I-C-D-D-L-K-D-G-K-I-V-I-V-N-S-I-E-L-D-P-K-V-G-Q-R-L-V-D-F-V-S-G-A-T-Y-S-L-N-G-T-L-E-E-I-E-K-G-I-Y-I-L-S-P-S-N-V-E-V-D-S-E-L-K-N-Q-L-S-S-K-G-M-F-S-W-N-R


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-S-A-G-D-L-R-K-G-N-T-F-E-L-D-G-Q-V-Y-T-V-V-D-F-L-H-V-K-P-G-K-G-A-A-F-V-R-T-K-L-R-N-V-L-N-G-G-L-K-E-T-T-F-N-P-T-E-K-F-Q-E-A-V-I-E-R-K-E-M-Q-Y-L-Y-T-D-G-E-L-Y-Y-F-M-D-Q-Q-T-F-E-Q-I-P-L-N-F-E-Q-V-E-G-A-I-K-F-L-K-E-N-M-F-A-I-I-K-F-Y-K-G-E-A-F-S-V-E-A-P-N-F-V-E-L-Q-I-T-H-T-D-P-G-A-K-G-N-T-A-T-N-V-M-K-P-A-T-V-E-T-G-A-V-V-H-V-P-L-F-I-N-E-G-D-S-I-R-I-D-T-R-T-G-E-Y-M-E-R-V


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-K-R-K-K-S-R-E-M-T-M-Q-L-L-F-E-M-M-I-K-K-E-N-Y-V-E-I-I-N-T-L-K-E-A-L-T-E-E-E-D-I-N-S-I-L-G-E-K-K-E-M-D-E-E-R-I-D-L-D-E-V-D-L-E-Y-L-I-H-T-L-K-G-V-E-E-N-S-K-V-L-D-E-H-I-E-K-Y-L-K-N-W-T-L-N-R-L-A-K-V-D-L-A-I-L-R-L-C-S-Y-E-I-L-F-S-N-E-V-P-D-N-V-A-I-N-E-G-V-E-L-A-K-K-Y-G-D-D-K-S-P-A-F-I-N-A-V-L-D-K-I-A-K-Q-M


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-V-T-R-H-E-K-I-L-E-L-I-E-R-K-D-I-E-T-Q-E-E-L-A-E-E-L-R-K-S-G-I-E-I-T-Q-A-T-V-S-R-D-I-K-E-L-K-L-I-K-V-L-G-E-Q-G-K-Y-K-Y-A-A-I-V-K-N-E-N-D-L-S-D-K-L-A-N-I-F-S-H-S-V-V-S-V-E-N-I-N-N-F-V-V-V-K-T-L-S-G-S-G-N-A-A-A-E-A-I-D-S-L-N-F-K-E-I-A-G-T-I-A-G-D-N-T-I-F-I-M-A-R-T-S-E-Q-A-F-E-I-V-K-K-M-K-R-V-I-R-E-R-G-V


### FUNCTION Participates in chromosomal partition during cell division May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves ### SEQUENCE -M-K-Q-M-N-Y-I-I-N-E-E-N-E-L-R-F-F-S-I-I-E-S-L-L-F-A-S-G-E-P-L-G-L-K-D-I-S-E-I-I-E-L-N-T-L-D-T-K-E-I-L-Q-K-M-I-R-E-Y-E-I-E-K-R-G-I-K-L-I-E-I-E-K-K-Y-Q-L-V-T-K-E-E-N-S-C-F-I-E-Q-L-L-K-T-N-S-S-Q-S-L-S-Q-A-A-L-E-T-L-S-I-V-A-Y-K-Q-P-V-T-R-V-D-V-D-E-I-R-G-V-K-S-D-R-A-L-Q-T-L-L-Q-K-S-L-I-K-E-T-G-R-L-D-V-P-G-R-P-I-L-Y-S-T-T-E-E-F-L-K-H-F-G-L-E-S-I-K-E-L-P-S-L-E-E-L-L-E-E-F-Q-E-E-D-L


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-Y-R-A-G-R-I-N-E-E-V-K-K-E-I-S-S-I-I-R-M-D-L-K-D-P-R-I-S-A-M-V-S-V-T-K-V-D-V-T-K-D-Q-R-Y-A-K-V-Y-V-S-I-F-G-D-E-K-S-K-E-E-T-L-E-A-L-K-S-S-S-G-F-I-R-R-E-V-G-H-R-I-K-L-R-Y-T-P-E-I-I-I-Q-N-D-D-S-I-E-H-G-M-H-I-D-S-I-L-D-K-I-K-E-N-E-D-H-D-N-K


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-N-N-K-T-F-I-D-N-L-K-E-L-T-E-P-I-V-N-D-L-D-Y-E-L-Y-Y-L-E-F-V-N-E-N-K-E-N-Y-L-R-I-Y-I-D-S-E-S-G-I-G-L-E-D-C-E-K-V-S-R-A-V-S-A-M-L-D-E-K-D-P-I-D-T-S-Y-Y-L-E-V-S-S-P-G-L-E-R-Q-L-Y-D-D-K-H-I-E-D-N-I-G-K-T-A-C-V-R-L-E-S-L-F-N-G-G-R-K-F-E-G-K-L-K-S-F-D-N-E-N-L-T-L-E-I-N-A-E-D-F-K-I-P-R-K-K-I-K-R-I-N-L-I-Y-E-G


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-L-K-E-I-M-N-T-A-E-D-K-M-S-K-A-L-L-A-L-K-K-D-L-A-S-L-K-A-G-R-A-N-P-A-M-L-D-K-I-E-A-E-Y-Y-G-T-M-T-P-L-S-Q-L-A-N-I-S-V-P-E-A-R-I-L-Q-I-Q-P-W-D-K-S-S-L-K-A-I-E-K-A-I-L-V-S-D-L-G-L-N-P-N-N-D-G-T-I-I-R-L-I-I-P-E-L-T-E-E-T-R-R-N-I-V-K-T-V-K-K-Y-G-E-D-T-K-I-A-I-R-S-V-R-R-D-G-N-D-K-I-K-D-L-K-S-D-M-S-E-D-D-I-K-K-A-E-E-E-I-Q-K-I-T-D-N-Y-V-K-K-V-D-E-M-I-D-I-K-E-K-E-I-M-S-I


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-L-D-V-I-K-A-I-E-A-E-Q-I-R-T-D-L-P-A-F-K-V-G-D-T-V-K-V-H-V-K-I-K-E-G-T-R-E-R-I-Q-V-F-E-G-T-V-I-K-R-Q-N-G-G-L-R-E-T-F-T-V-R-R-L-A-Y-G-V-G-V-E-R-T-F-P-V-N-A-P-T-V-S-K-I-E-I-V-R-K-G-K-V-R-R-A-K-L-F-Y-L-R-D-R-V-G-K-A-A-K-V-K-E-R-R-Y


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-Q-F-L-K-I-G-L-I-I-N-T-H-G-L-K-G-E-L-K-V-N-P-Q-T-D-N-I-D-R-F-K-K-L-K-R-V-Y-I-A-G-E-E-K-Q-V-E-G-C-K-F-L-N-D-K-V-V-L-K-I-Q-G-I-D-G-I-E-I-A-N-K-Y-R-N-K-Y-I-E-V-K-R-E-D-A-V-E-L-P-E-G-R-Y-Y-V-A-D-I-I-G-C-K-V-L-D-E-D-G-N-Y-L-G-K-V-K-E-V-I-H-T-K-N-N-D-V-Y-W-V-E-G-K-K-E-L-L-I-P-V-L-K-T-I-V-V-K-I-D-I-E-N-E-E-I-I-I-K-P-V-K-T-W-L-L-E


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-I-R-N-L-R-F-L-G-D-E-L-L-R-K-K-S-R-R-V-E-K-I-D-D-R-I-Q-A-L-L-D-D-M-L-D-T-M-Y-E-N-N-G-V-G-L-A-A-P-Q-V-G-I-L-K-R-V-V-V-I-D-I-G-E-G-P-L-F-L-I-N-P-E-I-I-E-Q-E-G-S-Y-I-E-Q-E-G-C-L-S-V-P-G-R-Q-G-E-V-E-R-P-Y-R-V-K-V-K-A-Q-N-R-D-G-K-E-I-I-V-E-G-E-E-F-L-A-K-A-L-C-H-E-I-D-H-L-N-G-V-L-F-V-D-K-I-I-D-V-K-G-E


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-E-Y-T-L-K-I-K-L-L-K-E-D-A-K-L-P-Q-Y-A-H-D-N-D-A-G-M-D-L-F-S-T-E-D-K-I-I-N-P-G-K-H-A-L-I-L-T-G-I-S-I-E-L-P-E-N-T-E-A-Q-I-R-P-R-S-G-L-A-L-K-N-G-V-T-V-L-N-T-P-G-T-I-D-A-G-Y-R-G-E-I-G-I-I-L-I-N-H-G-E-K-N-F-Q-V-E-K-G-M-K-I-A-Q-M-V-I-K-P-I-V-K-V-N-I-E-E-V-K-M-L-S-E-S-Q-R-G-K-G-G-F-G-S-T-G-K


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-Y-C-S-Y-N-E-S-K-V-V-D-S-R-S-T-E-D-S-I-S-I-R-R-R-R-E-C-L-E-C-G-K-R-Y-T-T-Y-E-K-I-E-S-V-P-I-L-V-I-K-K-N-L-N-R-E-Y-F-D-R-D-K-I-V-N-G-M-I-K-A-C-Q-K-R-P-V-S-R-Q-Q-I-E-E-I-V-D-E-I-E-K-K-I-N-N-S-M-I-T-E-V-K-S-E-Y-I-G-E-L-I-M-E-K-L-K-D-I-D-E-V-S-Y-V-R-F-A-S-V-Y-R-Q-F-K-D-I-N-T-F-M-E-E-I-K-K-L-K-D-R-E-L


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-D-P-F-G-S-S-S-V-P-P-C-S-T-S-D-L-P-E-P-K-L-Y-F-V-R-L-S-P-H-A-V-P-P-V-R-A-T-H-G-A-A-G-Y-D-L-F-S-A-Y-D-I-K-V-P-A-R-G-R-A-L-V-P-T-D-L-V-F-Q-F-P-P-G-C-Y-G-R-I-A-P-R-S-G-L-A-A-K-F-F-I-D-V-G-A-G-V-I-D-P-D-Y-R-G-N-V-S-V-V-L-F-N-F-S-E-S-S-F-N-I-R-R-G-D-R-V-A-Q-L-I-L-E-R-I-M-V-P-E-L-S-E-L-T-Q-L-G-E-T-D-R-G-A-S-G-F-G-S-T-G-M-G-A-V-D-R-N-Q-R-S-V-L-E-W-L-T-P-G-S-R


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-R-I-L-G-L-D-V-G-D-R-T-I-G-V-A-I-S-D-P-L-G-W-T-A-Q-G-V-K-T-I-K-R-S-N-L-K-N-D-I-K-E-I-E-D-I-C-N-E-Y-K-V-D-K-I-V-S-G-L-P-K-N-M-N-G-T-L-G-P-Q-S-E-K-V-T-E-F-C-D-I-L-K-K-E-L-E-K-E-I-I-M-W-D-E-R-L-T-T-V-A-A-H-K-A-M-I-E-G-D-L-S-R-A-K-R-K-K-I-V-D-K-I-A-A-I-Y-I-L-Q-G-Y-L-D-S-V-Y-N-K


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-S-R-L-E-N-L-T-S-K-I-I-K-D-S-E-E-K-A-K-I-I-L-D-E-A-K-R-E-E-E-K-I-M-L-G-Q-K-Q-E-G-E-S-I-K-S-K-I-I-E-K-A-Y-L-E-S-K-N-R-K-E-R-I-I-S-N-S-H-L-F-V-R-N-R-K-L-E-A-K-Q-E-V-I-D-K-V-Y-K-E-A-L-N-K-L-A-K-L-N-K-E-E-Y-L-N-F-I-K-D-S-I-L-A-L-E-I-Y-G-D-E-E-I-I-L-S-Q-D-E-K-Y-I-N-K-E-T-I-E-E-I-N-K-E-L-K-S-K-G-K-K-G-E-I-K-I-S-D-K-K-R-D-F-R-G-G-F-I-L-N-K-D-G-I-E-I-N-N-T-F-E-A-L-I-L-S-L-K-D-D-L-E-P-V-I-I-D-T-L-F-S


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-A-E-I-L-I-A-T-E-R-N-E-K-G-K-T-A-R-K-K-G-F-I-P-G-I-I-Y-G-K-D-R-E-G-Q-S-I-N-F-E-R-G-K-L-I-A-F-L-K-E-K-G-E-K-S-K-M-N-F-Q-L-N-G-E-N-K-Q-G-I-I-K-E-V-G-R-D-A-V-T-S-S-I-I-H-I-D-I-Q-E-V-S-A-L-E-K-V-R-W-T-I-P-I-F-F-E-G-R-E-Q-L-K-K-K-E-L-Y-I-Q-V-Y-L-T-E-V-E-V-E-G-K-A-S-D-I-P-N-N-I-T-L-N-V-G-N-L-E-L-G-E-E-V-K-V-K-D-L-N-I-G-S-N-I-R-I-F-N-E-L-E-N-T-I-A-I-I-S-S-S-Q-N-T-N-K-N-I-E-E-E-D-P-S-E-V-E


### FUNCTION Plays a role in nuclear translocation of the viral pre-integration complex ### SEQUENCE -M-D-P-R-E-R-V-P-P-G-N-S-G-E-E-T-V-G-E-A-F-E-W-L-E-T-T-L-E-H-L-N-R-V-A-V-N-H-L-P-R-E-L-I-F-Q-V-W-Q-K-S-W-A-Y-W-R-E-E-Q-G-M-S-I-S-Y-T-K-Y-R-Y-L-C-L-M-Q-K-A-M-F-I-H-F-A-K-G-C-G-C-L-R-E-G-H-G-P-G-G-W-R-S-G-P-P-P-P-P-P-P-G-L-A


### FUNCTION Mediates the nuclear export of encapsidated genomic RNAs  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain This domain is believed to allow recognition of RNPs bound to the protein M1 Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane May down-regulate viral RNA synthesis when overproduced ### SEQUENCE -M-D-P-N-T-V-S-S-F-Q-D-I-L-M-R-M-S-K-M-Q-L-G-S-S-S-E-D-L-N-G-I-I-T-Q-F-E-S-L-K-L-Y-R-D-S-L-G-E-A-V-M-R-M-G-D-L-H-S-L-Q-N-R-N-G-K-W-R-E-Q-L-G-Q-K-F-E-E-I-R-W-L-I-E-E-V-R-H-R-L-K-I-T-E-N-S-F-E-Q-I-T-F-M-Q-A-L-Q-L-L-L-E-V-E-Q-E-I-R-T-F-S-F-Q-L-I


### FUNCTION Involved in host translation shutoff without degradating host RNA By suppressing host gene expression, facilitates the evasion from host type I interferon immune response ### SEQUENCE -M-N-N-S-K-D-N-P-F-R-G-A-I-A-R-K-A-R-I-Y-L-R-E-G-L-D-C-V-Y-F-L-N-K-A-G-Q-A-E-P-C-P-A-C-T-S-L-V-F-Q-G-K-T-C-E-E-H-I-H-N-N-N-L-L-S-W-Q-A-V-K-Q-L-E-K-Q-T-P-Q-R-Q-S-L-N


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-N-I-I-E-G-K-L-I-G-Q-S-L-K-F-G-I-T-I-G-R-F-N-E-F-I-G-G-K-L-L-D-G-A-V-D-A-L-I-R-H-G-V-D-E-K-D-I-E-I-A-W-V-P-G-A-F-E-I-P-L-I-A-K-K-M-A-K-S-K-K-Y-D-G-I-I-C-L-G-A-V-I-R-G-A-T-T-H-Y-D-Y-V-A-S-E-V-S-K-G-I-A-K-I-T-L-D-E-E-V-P-V-I-F-G-V-L-T-T-E-N-I-E-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-Y-E-A-A-C-T-A-I-E-M-A-N-I-I-N-I-I


### FUNCTION Cell-to-cell movement function ### SEQUENCE -M-A-C-C-R-C-D-S-S-P-G-D-Y-S-G-A-L-L-I-L-F-I-S-F-V-F-F-Y-I-T-S-L-S-P-Q-G-N-T-Y-V-H-H-F-D-S-S-S-V-K-T-Q-Y-V-G-I-S-T-N-G-D-G


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-D-F-Y-S-L-F-L-I-A-I-A-L-S-L-D-A-F-G-V-A-L-C-I-G-L-N-N-N-V-D-L-K-Y-K-S-S-C-A-I-Y-F-G-F-F-Q-F-L-F-A-I-I-G-G-Y-A-G-F-L-F-N-K-Y-I-A-T-M-P-Q-I-V-G-G-V-V-I-C-I-V-G-I-I-M-I-K-E-G-I-E-N-E-D-S-C-K-I-L-K-P-G-M-N-I-I-L-G-I-S-V-S-I-D-A-M-V-V-G-F-T-A-L-N-K-I-Q-S-G-L-L-I-L-R-D-T-L-F-I-G-I-V-T-L-F-V-S-I-L-A-F-I-T-S-K-Y-L-K-K-I-D-V-I-G-K-Y-A-D-Y-I-G-G-I-I-L-I-F-F-G-L-K-M-I-F-F


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-F-K-D-V-V-E-E-F-K-K-F-A-I-K-G-N-A-I-D-L-A-V-G-V-V-I-G-G-A-F-G-K-I-V-T-S-L-V-Q-D-I-I-M-P-A-V-G-L-L-L-G-K-V-N-F-K-T-L-S-L-T-V-T-S-I-D-G-S-E-I-V-L-K-Y-G-Q-F-I-Q-S-V-V-D-F-I-I-I-S-F-S-I-F-L-F-V-K-L-I-N-S-F-K-K-K-E-E-E-K-P-K-V-E-E-P-S-K-E-E-K-L-L-A-E-I-R-D-I-L-K-E-S-K


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-V-K-G-R-S-N-K-T-L-A-E-N-R-K-A-R-H-D-Y-F-V-E-E-A-Y-E-A-G-I-E-L-V-G-T-E-V-K-S-I-R-E-G-K-A-N-L-K-D-S-Y-A-E-I-R-N-G-E-V-F-L-R-N-M-H-V-S-P-Y-E-Q-G-N-I-F-N-K-D-P-L-R-D-R-K-L-L-L-H-K-M-Q-I-L-K-L-T-A-Y-T-T-Q-Q-G-Y-T-L-I-P-L-S-L-Y-L-K-N-G-R-V-K-V-N-L-A-V-A-K-G-K-K-N-Y-D-K-R-Q-D-L-I-E-K-A-A-K-R-D-I-E-R-E-L-K-D-R-S-R-Y


### FUNCTION Minor structural protein present in one or two copies per virion Does not seem to play a role in capsid assembly, but is essential for production of infectious virus ### SEQUENCE -M-A-F-L-M-S-E-F-I-G-L-G-L-A-G-A-S-V-L-S-N-A-L-L-R-R-Q-E-L-Q-L-Q-R-Q-A-L-E-N-G-L-V-L-K-A-D-Q-L-G-R-L-G-F-N-P-N-E-V-K-N-V-I-V-G-N-S-F-S-S-N-V-R-L-S-N-M-H-N-D-A-S-V-V-N-A-Y-N-V-Y-N-P-A-S-N-G-I-R-K-K-I-K-S-L-N-N-S-V-K-I-Y-N-T-T-G-E-S-S-V


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-F-L-L-V-G-L-G-N-P-G-K-E-Y-E-K-T-R-H-N-I-G-F-E-A-V-D-K-I-S-Y-E-Y-N-I-P-I-K-R-E-R-F-K-G-V-F-G-D-G-R-I-S-N-E-K-V-I-L-L-K-P-T-T-Y-M-N-L-S-G-E-S-L-R-E-I-I-E-Y-Y-N-I-P-I-T-N-V-I-V-I-Y-D-D-V-D-L-E-V-G-R-L-R-I-R-T-K-G-S-A-G-G-H-N-G-I-K-S-I-I-Y-N-L-N-S-E-D-F-I-R-L-R-I-G-V-G-K-P-Q-R-D-M-V-S-H-V-L-G-K-F-A-K-E-D-E-K-N-I-E-E-V-L-K-I-I-P-E-L-A-Y-T-I-I-N-Q-G-P-Q-E-A-M-N-K-Y-N-N-F-R-A-E


### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-K-G-V-K-F-M-K-E-I-I-L-A-G-G-C-F-W-G-V-E-E-Y-F-S-R-I-Y-G-V-V-D-T-K-V-G-Y-V-N-G-V-T-K-N-P-S-Y-E-E-V-C-N-G-N-T-G-Y-A-E-G-C-Y-I-K-F-D-E-S-I-I-G-L-K-R-I-L-D-K-F-W-D-I-I-D-P-T-I-L-N-R-Q-G-P-D-V-G-H-Q-Y-R-T-G-I-Y-Y-Y-D-K-E-D-L-D-D-I-L-K-S-K-D-E-I-S-K-K-Y-D-K-P-I-V-T-E-V-E-K-V-T-Y-F-Y-L-A-E-E-Y-H-Q-K-Y-L-K-K-N-P-N-G-Y-C-H-I-N-L-D-N


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-L-K-D-V-K-K-L-G-K-K-D-D-V-V-N-V-S-D-G-Y-A-R-N-F-L-F-P-R-K-L-A-L-E-A-K-E-S-N-L-N-L-L-N-N-K-K-E-A-E-R-K-Q-K-L-A-E-L-E-E-A-Q-K-L-A-E-E-L-K-N-Q-E-L-I-L-K-V-K-S-G-D-N-G-K-L-F-G-S-I-T-G-K-D-I-S-D-E-L-K-K-K-F-K-L-D-I-D-R-R-K-I-N-V-E-N-I-R-Q-L-G-V-Y-D-V-E-I-K-L-Y-P-E-V-S-T-K-I-K-V-K-I-E-D-I


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-R-G-G-V-P-N-F-G-G-G-N-I-N-N-L-M-K-Q-A-Q-K-F-Q-Q-Q-M-E-E-M-Q-G-Q-L-E-N-K-K-F-Q-A-S-V-G-G-G-A-V-T-A-I-A-N-G-K-K-E-I-V-D-I-R-I-K-P-E-V-V-D-P-D-D-V-E-M-L-E-D-L-I-L-S-A-C-N-E-A-L-K-K-A-E-H-E-T-A-N-E-M-K-K-L-T-G-G-M-N-L-P-G-M-F


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-E-F-Y-P-I-A-I-E-K-L-I-E-E-F-A-K-L-P-G-I-G-K-K-T-A-Q-R-L-T-L-Y-V-L-N-L-P-R-E-E-V-E-E-F-A-N-A-L-I-K-A-R-G-T-I-K-Y-C-S-V-C-G-N-F-T-D-K-D-P-C-A-I-C-S-N-P-N-R-D-K-N-T-I-C-V-V-E-H-P-K-D-I-M-T-M-E-K-V-R-E-Y-N-G-M-Y-H-V-L-H-G-T-I-S-P-M-A-G-R-G-P-N-D-I-K-L-K-E-L-I-S-R-I-N-G-E-I-K-E-V-I-V-A-T-N-P-N-V-E-G-E-A-T-A-M-Y-I-S-K-I-L-K-P-L-G-A-K-V-T-R-I-A-H-G-I-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-A-K-A-L-E-G-R-K-E-I


### FUNCTION May mediate protein transfer from the Sec translocon to the chaperone network via its extracellular C-terminal region ### SEQUENCE -M-I-K-N-S-Y-I-N-E-K-L-N-F-Y-Q-K-S-F-L-T-C-M-L-L-I-V-I-V-I-V-Y-F-F-S-K-N-Y-L-D-K-P-K-N-S-Y-V-H-T-K-M-M-T-F-L-T-N-S-N-E-L-N-I-S-K-N-L-I-W-T-K-K-T-I-S-G-N-L-M-S-L-K-L-A-K-V-Y-V-I-N-N-Q-L-E-K-A-L-K-I-L-E-K-S-K-N-N-S-V-D-L-N-F-F-N-L-I-S-F-K-I-A-Q-I-Y-F-Q-K-N-N-I-K-K-A-I-T-T-I-K-D-I-L-G-D-S-W-D-S-I-R-N-N-F-I-G-D-V-Y-F-K-L-D-N-Q-K-R-A-V-T-L-W-K-R-S-I-I-Q-N-K-K-I-E-F-E-K-I-I-Q-M-K-I-N-N-Y-N


### FUNCTION Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-P-K-L-I-I-L-P-H-K-I-L-L-P-K-G-G-V-F-N-A-M-K-G-E-S-I-L-N-V-A-L-R-N-N-V-E-I-E-H-A-C-E-K-S-C-V-C-T-T-C-H-C-Y-I-W-K-G-A-S-S-L-S-I-C-E-E-K-E-E-D-V-L-D-K-A-W-N-L-Q-F-N-S-R-L-S-C-Q-A-K-I-N-N-K-D-I-E-I-E-I-P-K-Y-T-I-N-Q


### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-Y-F-K-L-F-N-L-P-Q-K-F-E-L-D-V-N-N-L-T-S-Q-Y-Y-N-L-Q-K-K-F-H-P-D-S-Y-Q-D-K-N-I-Y-T-K-K-Y-L-E-K-S-M-L-L-N-Q-G-Y-Q-T-L-K-N-M-L-T-R-A-E-H-L-L-F-L-N-N-Y-K-V-D-K-K-K-K-I-V-F-N-A-K-F-L-E-M-Q-I-E-L-F-E-R-L-E-I-H-K-N-K-N-N-K-H-E-I-N-K-I-L-L-E-V-S-Q-I-E-K-N-Y-I-K-K-L-K-N-F-C-N-L-E-K-W-K-I-A-H-S-I-L-Y-K-L-L-F-L-T-K-F-I-K-K-T-K-K-I-Q-H-E-I-I-N