### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-T-V-R-D-V-I-Q-K-I-E-P-R-M-K-K-T-I-E-A-F-Q-H-E-L-A-S-I-R-T-G-K-A-T-T-A-L-L-D-R-V-K-V-E-A-Y-G-S-Q-M-P-L-K-Q-V-G-N-V-G-V-L-D-A-H-T-L-T-V-Q-V-W-D-K-S-M-V-G-A-T-E-R-A-I-R-D-A-G-L-G-L-N-P-S-A-D-G-Q-N-I-R-I-S-I-P-P-L-T-E-E-R-R-K-E-F-V-K-L-T-K-K-F-G-E-D-S-K-V-S-L-R-N-H-R-R-D-L-I-H-E-V-E-K-L-E-K-E-K-L-I-S-E-D-E-L-K-R-G-K-K-D-A-D-D-L-L-H-K-Y-E-K-Q-I-T-E-L-I-A-Q-K-E-K-E-I-M-E-V


### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-P-E-I-H-P-K-Y-T-K-V-T-V-N-C-A-N-C-G-T-T-F-E-T-R-S-T-R-N-N-N-I-K-V-D-I-C-S-K-C-H-P-F-Y-T-G-K-Q-V-L-V-D-T-A-G-R-V-D-R-F-N-K-R-F-A-K-A-A-P-K-A-S-A-Q


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Q-A-L-I-E-I-S-D-K-Q-Y-L-V-K-A-G-D-K-I-F-V-P-K-Q-K-A-A-A-G-D-V-I-E-V-K-T-L-M-Q-V-N-Q-A-D-S-A-L-K-A-G-T-A-T-I-K-V-L-E-H-V-R-D-E-T-I-I-V-F-R-K-K-R-R-K-R-F-Q-K-R-N-G-H-R-Q-H-M-T-Q-V-E-V-L-S-L


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-R-K-H-H-K-E-Q-E-E-I-Q-E-Q-E-T-I-S-A-G-A-A-E-T-P-A-E-E-T-A-A-I-P-A-A-T-E-A-D-M-D-A-E-I-S-A-R-D-A-E-I-Q-K-L-R-E-E-V-M-R-R-A-A-E-F-E-N-F-R-K-Q-K-E-R-E-A-A-L-S-G-T-R-M-L-E-N-I-V-R-E-L-L-P-L-I-D-D-L-K-R-L-M-S-H-I-P-A-E-M-Q-A-M-A-E-A-K-P-F-I-E-G-V-E-L-I-H-K-N-F-M-S-L-L-E-R-K-G-V-K-E-I-E-A-K-G-K-M-L-D-V-N-F-H-E-A-I-T-Q-I-D-A-P-G-A-E-P-D-T-I-V-E-E-Y-Q-T-G-Y-T-L-G-D-R-V-I-R-H-A-K-V-I-V-A-K


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-I-L-P-I-N-T-Y-S-D-P-V-L-A-M-K-A-K-P-L-K-G-V-D-S-A-I-E-E-L-I-A-E-M-F-D-T-M-Y-K-A-P-G-I-G-L-A-A-P-Q-V-G-H-S-L-R-L-V-V-V-D-I-S-T-I-K-E-Y-A-D-F-K-P-M-V-V-I-N-P-R-I-V-A-V-R-G-R-S-L-M-E-E-G-C-L-S-V-P-G-I-A-G-N-V-V-R-P-S-A-I-T-L-H-Y-R-D-E-K-F-E-E-H-T-A-D-F-H-S-M-M-A-R-V-L-Q-H-E-I-D-H-L-D-G-T-L-F-V-D-R-M-D-K-R-D-R-R-K-I-Q-K-E-L-D-A-I-A-E-G-R-V-K-A-D-Y-P-L-A-R-D-V-N-R-V-E-A-E-A


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-D-R-I-Y-L-T-R-D-G-Y-N-R-L-K-E-E-L-H-L-L-M-T-E-T-R-K-E-V-L-E-K-I-A-E-A-R-S-H-G-D-L-S-E-N-A-E-Y-D-A-A-R-E-E-Q-S-Q-L-E-A-K-I-G-E-I-E-N-K-L-A-S-A-T-I-L-D-P-K-Q-I-K-T-D-R-V-Y-I-L-T-S-V-K-L-R-N-L-D-A-E-D-E-I-I-E-Y-T-L-V-S-S-E-E-A-D-S-D-L-G-K-I-S-V-R-S-P-V-G-R-S-L-I-G-K-S-V-G-D-K-V-T-I-S-V-P-K-G-E-L-H-Y-E-I-L-D-I-F-V-K


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-P-L-Q-I-F-N-T-T-K-R-T-I-D-E-T-L-L-A-E-V-I-R-L-V-I-G-E-E-G-G-A-V-G-S-I-E-A-I-Y-C-G-N-K-M-I-R-R-I-N-R-D-F-L-G-H-D-Y-V-T-D-T-I-T-F-G-Y-N-E-G-G-E-V-D-G-E-F-Y-I-S-L-D-V-I-E-S-N-A-R-R-F-G-V-S-F-E-D-E-L-L-R-V-T-I-H-S-A-L-H-L-M-G-Y-D-D-E-T-S-E-L-R-A-A-M-S-L-R-E-D-H-Y-L-Y-R-L-R-H


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-E-T-R-A-L-S-V-N-L-R-E-V-K-K-N-G-A-A-K-L-R-R-L-G-Q-V-P-A-V-V-Y-H-K-G-E-A-T-V-A-I-S-V-E-E-I-S-L-N-K-L-V-H-S-S-E-S-H-M-I-D-L-Q-Y-P-D-G-K-S-V-R-S-F-I-K-D-V-Q-F-D-P-V-T-D-R-V-I-H-A-D-F-Q-L-F-S-T-D-E-V-V-E-M-E-V-P-I-H-L-E-G-E-C-P-G-V-K-I-G-G-G-K-I-Q-I-N-V-H-T-L-P-L-K-G-K-P-E-A-M-P-E-H-F-T-I-D-V-S-A-L-E-L-G-Q-T-L-H-I-R-D-L-Q-A-I-A-P-E-G-V-Q-I-L-G-D-A-D-T-S-V-V-S-V-V-A-P-R-K-E-A-E-T-A-A-E-G-A-T-A-E-A


### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-A-L-Y-I-T-E-E-C-T-Y-C-G-A-C-E-P-E-C-P-T-N-A-I-S-A-G-S-E-I-Y-V-I-D-A-A-S-C-N-E-C-A-G-F-A-D-S-P-A-C-V-A-V-C-P-A-E-C-I-V-Q-G


### FUNCTION Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions ### SEQUENCE -M-A-H-R-I-T-D-E-C-T-Y-C-A-A-C-E-P-E-C-P-V-S-A-I-S-A-G-D-S-I-Y-V-I-D-E-N-V-C-V-D-C-I-G-Y-H-D-E-P-A-C-V-A-V-C-P-V-D-C-I-I-K-V


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-K-L-I-V-G-L-G-N-P-E-L-R-H-A-A-T-R-H-N-I-G-F-D-V-I-D-H-L-A-G-S-S-T-F-S-S-G-K-G-N-Y-R-F-T-K-I-T-A-P-G-G-P-L-I-L-V-K-P-M-T-Y-M-N-L-S-G-H-A-V-V-A-A-M-N-F-W-K-I-E-R-E-N-L-L-V-I-C-D-D-V-N-I-P-L-G-T-I-R-I-R-A-K-G-S-A-G-G-Q-N-G-L-K-H-I-I-Q-S-L-G-S-E-E-F-A-R-L-R-V-G-V-G-G-E-N-M-P-A-S-L-S-S-F-V-L-S-K-F-T-A-E-E-R-K-C-I-D-K-V-I-P-V-C-A-D-A-V-L-D-F-A-S-L-G-V-E-H-A-M-T-K-Y-N-G-Q-V-C


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-L-K-E-F-R-E-F-A-L-K-G-N-V-V-D-M-A-V-G-I-I-I-G-G-A-F-G-A-L-V-N-S-L-V-N-D-L-L-M-P-P-L-G-L-L-L-K-G-V-D-F-S-N-L-F-V-V-L-K-E-G-T-P-P-G-P-Y-I-A-L-A-D-A-K-T-A-G-A-V-T-L-N-Y-G-L-F-V-N-A-L-I-G-F-L-I-M-A-F-A-V-F-L-L-V-R-S-I-N-R-L-R-S-L-S-E-K-S-A-A-P-A-V-A-P-Q-T-K-E-C-P-F-C-F-S-I-I-P-L-K-A-V-R-C-P-N-C-T-S-Q-L


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-L-F-L-T-G-V-V-L-K-P-K-G-L-K-G-E-L-K-V-K-P-V-T-D-F-P-E-S-F-L-T-R-R-E-Y-Y-I-G-K-T-P-E-D-A-V-L-R-K-V-Q-S-A-R-F-H-Q-G-F-A-W-L-V-F-E-G-A-G-S-R-E-G-A-E-A-L-V-G-C-G-L-Y-V-T-R-D-A-L-V-A-M-P-D-D-R-A-Y-I-H-E-L-I-G-L-D-V-F-D-E-T-E-G-R-V-G-K-I-S-D-V-L-Q-M-P-A-H-D-V-Y-E-V-D-T-G-D-R-K-V-L-I-P-A-V-E-D-F-I-T-E-T-D-L-E-K-G-M-V-R-L-K-R-F-K-E-F-L


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-D-Q-L-I-Q-L-V-E-A-T-Q-Q-R-N-D-I-P-E-V-R-P-G-D-T-V-R-I-Q-L-K-V-I-E-G-E-K-E-R-L-Q-A-F-E-G-V-V-I-G-D-K-G-M-G-A-S-K-T-I-T-V-R-K-I-S-H-G-V-G-V-E-R-I-I-P-V-N-S-P-N-I-E-S-V-T-V-V-R-S-G-K-A-R-R-A-K-L-F-Y-L-R-K-R-T-G-K-A-A-L-K-V-K-E-R-K-S-A-S-A-E-A


### FUNCTION CRISPR  Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-L-V-L-V-T-Y-D-V-N-T-E-T-P-A-G-R-R-R-L-R-R-I-A-K-T-C-Q-N-Y-G-Q-R-V-Q-F-S-V-F-E-C-N-V-D-P-A-Q-W-V-K-L-R-S-K-L-L-N-E-M-D-P-K-L-D-S-L-R-F-Y-F-L-G-S-N-W-Q-G-R-V-E-H-E-G-A-K-E-P-R-D-L-E-G-T-L-I-L


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-N-K-A-S-R-Q-K-K-I-R-E-L-I-E-N-H-E-V-S-G-Q-Q-E-L-L-G-M-L-E-K-E-G-I-V-V-A-Q-A-T-L-S-R-D-F-A-E-M-G-V-V-R-N-R-T-S-D-G-G-Y-R-L-A-V-P-E-E-P-Q-V-D-I-I-K-G-L-V-G-M-E-V-L-S-V-A-S-N-E-T-S-I-I-I-R-T-L-P-G-R-A-H-G-V-G-S-F-L-D-R-L-T-N-D-N-I-L-G-T-I-A-G-D-D-T-V-L-V-I-P-S-T-V-R-K-I-S-S-V-K-S-Y-I-Q-K-I-L-S-Q-P


### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-S-G-K-Y-F-E-A-T-D-Q-N-F-Q-A-E-I-L-N-S-D-K-V-A-L-V-D-F-W-A-A-W-C-G-P-C-M-M-L-G-P-V-I-E-E-L-A-G-D-Y-E-G-K-A-I-I-A-K-L-N-V-D-E-N-P-N-T-A-G-Q-Y-G-I-R-S-I-P-T-M-L-I-I-K-G-G-K-V-V-D-Q-M-V-G-A-L-P-K-N-M-I-A-K-K-L-D-E-H-I-G


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-A-M-P-N-F-G-D-M-M-K-Q-L-Q-E-A-G-A-K-M-Q-D-L-Q-K-Q-L-E-K-L-V-S-E-G-E-A-G-G-G-M-V-R-A-K-V-N-G-R-Q-K-L-L-E-L-T-I-D-P-E-I-M-D-D-V-D-M-V-Q-D-L-V-V-A-A-V-N-K-A-L-E-A-S-A-Q-L-A-Q-S-E-I-Q-K-A-A-G-G-M-I-N-P-A-D-L-M-K-Q-F-G-G-Q-G


### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-A-Q-T-L-D-D-L-I-R-T-S-E-L-P-V-F-I-D-F-W-A-D-W-C-G-P-C-K-M-V-A-P-S-V-K-Q-L-A-S-E-F-K-G-R-L-I-V-V-K-V-N-V-D-Q-Q-P-D-A-A-A-R-F-Q-V-Q-G-I-P-A-L-M-L-F-V-G-G-Q-L-K-W-R-T-A-G-A-I-P-Y-Q-Q-M-R-Q-E-V-L-K-A-I-G


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-S-K-K-Q-G-K-P-E-Y-V-T-A-I-S-N-R-K-A-R-F-E-Y-E-I-L-D-T-I-E-A-G-I-E-L-L-G-S-E-V-K-S-V-R-L-G-K-A-S-L-S-E-S-Y-A-M-I-H-H-G-Q-V-W-L-E-N-M-Q-I-T-P-Y-E-H-N-T-L-D-T-L-E-P-K-R-S-R-R-L-L-L-H-K-A-E-I-M-R-L-Q-S-K-I-S-E-K-G-L-T-L-I-P-L-K-A-Y-F-N-K-R-G-V-L-K-I-E-L-G-L-A-R-G-K-K-L-Y-D-K-R-E-T-I-K-N-R-D-A-K-R-Q-L-Q-Q-L-R-K-Q-Y


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-N-L-K-P-L-A-D-R-V-I-V-K-P-A-P-A-E-E-K-T-K-G-G-L-Y-I-P-D-T-G-K-E-K-P-M-Y-G-E-V-V-A-V-G-P-G-K-V-S-D-A-G-Q-V-V-A-M-Q-V-K-A-G-D-K-V-L-Y-G-K-Y-S-G-T-E-V-H-V-E-G-E-D-Y-L-I-M-R-E-S-D-I-F-A-I-L-G


### FUNCTION Transcriptional regulator ### SEQUENCE -M-S-D-L-Y-R-F-G-I-S-L-E-R-K-L-I-E-S-F-D-R-H-I-K-A-Q-G-Y-Q-S-R-S-E-A-L-R-D-L-I-R-E-E-L-L-R-K-T-T-A-E-G-G-L-V-A-G-A-I-V-M-T-Y-D-H-H-K-R-D-L-V-N-R-L-I-D-I-Q-H-D-F-H-D-L-I-I-S-T-Q-H-V-H-L-D-H-E-N-C-L-E-V-I-A-V-K-G-N-A-P-E-I-E-K-L-S-S-A-L-K-V-L-V-G-V-K-H-L-D-L-S-L-S-S-A-D


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-P-I-K-S-R-I-R-T-V-P-D-Y-P-K-K-G-I-M-F-R-D-I-T-T-L-I-K-D-P-V-G-F-R-L-V-I-D-N-M-T-Q-H-Y-L-S-N-G-V-D-F-D-A-I-V-G-I-E-S-R-G-F-I-L-G-G-A-L-A-Y-T-L-G-K-G-F-V-P-V-R-K-P-G-K-L-P-A-D-V-V-Q-L-E-Y-E-L-E-Y-G-T-D-K-I-E-M-H-T-D-A-L-V-Q-G-Q-R-V-L-L-V-D-D-L-L-A-T-G-G-T-A-L-A-A-A-G-L-V-E-K-L-G-G-V-V-A-S-M-A-F-I-V-N-L-P-D-I-G-G-E-K-K-I-R-E-K-G-Y-N-I-Y-F-L-T-E-F-E-G-D


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-L-H-K-S-A-E-K-R-L-R-Q-A-A-R-R-N-E-R-N-R-A-R-K-K-E-L-K-G-V-L-K-N-M-Q-K-L-I-D-A-N-A-A-K-S-E-V-E-A-A-Y-K-A-A-V-Q-K-L-D-R-L-G-V-K-R-Y-I-H-P-N-K-A-S-R-K-K-A-Q-L-T-K-A-L-N-N-Y-T-P-T-A-S


### FUNCTION Essential for recycling GMP and indirectly, cGMP ### SEQUENCE -M-S-A-E-Q-V-L-D-Q-G-R-L-I-V-F-S-A-P-S-G-T-G-K-S-T-V-A-K-L-V-M-E-R-L-G-S-L-E-F-S-V-S-A-T-T-R-Q-M-R-A-G-E-R-D-G-V-D-Y-H-F-L-S-R-E-E-F-E-K-K-I-A-E-N-G-F-I-E-H-E-F-F-F-G-N-F-Y-G-T-L-L-D-K-T-I-D-A-I-K-A-G-H-N-L-L-F-D-L-D-V-K-G-A-L-N-L-K-R-I-F-G-D-Q-A-L-L-V-F-L-K-P-P-S-M-E-E-L-A-R-R-L-Q-A-R-D-S-E-S-A-E-A-L-K-S-R-L-E-R-A-E-M-E-L-S-H-A-G-E-F-D-F-V-V-V-N-D-D-L-G-R-T-V-D-A-V-A-T-R-I-A-E-F-L-P-Q-P


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-G-L-T-K-E-H-K-T-E-I-I-T-K-F-G-D-S-A-T-D-T-G-K-A-E-V-Q-V-A-L-F-T-R-R-I-T-D-L-T-G-H-L-Q-Q-H-P-K-D-K-H-S-R-R-G-L-L-M-L-V-G-K-R-K-R-V-L-N-Y-L-K-K-V-D-I-E-R-Y-R-K-V-L-A-D-L-D-L-R-K


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-I-R-T-D-K-V-S-S-L-L-Q-R-E-L-S-A-I-F-E-K-E-L-P-R-S-G-P-L-V-T-V-T-E-V-R-M-T-A-D-L-G-I-A-R-V-Y-V-S-V-I-G-S-E-A-Q-R-A-E-V-M-E-Y-L-D-A-E-N-K-M-I-R-K-T-L-S-A-K-I-R-H-Q-F-R-R-I-P-E-L-E-F-Y-E-D-R-L-F-E-Q-A-N-R-I-E-Q-L-L-K-S-V-K-P-A-R-D-E-E-Q-H


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-T-D-D-L-I-K-K-A-I-G-E-T-I-G-E-L-S-A-T-S-G-E-E-I-Y-V-V-E-A-A-I-R-A-G-G-R-K-I-E-L-T-V-D-T-D-K-G-V-S-I-D-Q-C-A-K-L-S-R-A-I-R-A-R-L-E-A-C-E-E-D-S-M-L-S-S-G-E-F-D-L-M-V-S-S-P-G-I-G-E-P-I-Q-V-Q-R-Q-Y-L-R-H-L-G-R-L-I-R-V-N-Y-L-D-E-E-E-Q-P-K-E-I-T-G-K-L-L-E-A-A-V-G-P-E-A-E-Q-P-S-I-T-I-E-A-V-K-E-G-R-K-K-R-T-A-G-E-P-P-V-T-I-R-L-A-D-V-V-R-A-V-V-Q-T-E-L


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-V-S-I-S-N-V-S-R-G-A-I-I-R-W-N-G-A-P-H-S-I-E-S-L-V-H-R-T-P-G-N-L-R-A-F-Y-Q-A-S-M-K-N-L-K-T-G-R-N-V-E-Y-R-F-S-A-T-E-Q-V-D-V-I-V-T-E-R-K-K-Y-Q-Y-L-Y-R-D-G-E-D-Y-V-M-M-D-T-E-T-F-D-Q-I-N-V-P-E-V-A-I-G-P-A-S-R-F-L-K-D-S-V-M-V-D-I-V-F-A-D-D-G-S-I-L-E-V-E-L-P-T-F-V-E-L-E-V-T-E-T-S-P-A-S-K-D-D-R-A-T-S-G-T-K-P-A-I-V-E-T-G-A-E-V-N-V-P-M-F-I-Q-T-G-S-I-I-R-I-D-T-R-S-G-E-Y-M-E-R-V-K-K


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-S-I-E-T-L-V-E-E-I-G-K-L-T-L-T-E-A-S-E-L-V-K-A-L-E-E-K-F-G-V-S-A-A-P-A-V-M-A-G-A-V-M-A-A-P-A-G-E-A-A-A-A-E-E-K-T-E-F-D-V-V-L-K-S-A-G-A-N-K-I-N-V-I-K-V-V-R-A-I-T-G-L-G-L-K-E-A-K-D-M-V-D-G-A-P-K-T-V-K-E-A-V-S-K-D-E-A-E-K-I-A-K-E-L-K-D-A-G-A-E-V-E-L-N


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-M-K-R-D-T-K-E-Q-I-A-Q-E-I-A-E-K-F-Q-K-S-Q-G-F-Y-F-T-E-F-Q-G-L-D-V-Q-K-M-S-Q-L-R-L-E-F-R-K-A-G-I-E-Y-R-V-V-K-N-T-L-I-K-K-A-L-K-D-A-A-D-V-D-K-L-A-A-G-L-K-N-T-T-A-V-A-F-A-Y-D-D-P-I-A-P-A-K-I-I-K-K-F-S-K-D-N-E-A-L-K-F-K-M-A-S-I-D-G-Q-V-F-G-S-D-S-L-P-Q-L-S-E-M-L-S-K-T-E-N-I-G-R-L-A-G-L-L-N-N-M-V-A-S-V-P-M-V-M-N-A-V-M-R-N-L-V-S-V-I-D-Q-V-G-K-L-E-K


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-I-T-G-F-I-K-L-Q-I-P-A-G-G-A-N-P-A-P-P-V-G-P-A-L-G-Q-K-G-V-N-I-M-E-F-C-K-Q-F-N-A-K-T-Q-S-E-A-G-M-I-I-P-V-V-I-T-V-Y-S-D-K-S-F-T-F-V-T-K-T-P-P-A-A-V-L-L-L-K-E-A-K-L-Q-K-G-S-G-E-P-N-R-N-K-V-G-T-V-T-M-D-Q-V-R-K-I-A-E-L-K-R-P-D-L-N-S-I-D-L-E-G-A-T-Q-M-V-I-G-T-A-R-S-M-G-I-V-V-E-G


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-S-S-S-S-H-K-R-I-I-G-I-D-F-G-T-K-R-I-G-V-A-L-S-D-P-L-R-M-F-A-Q-P-L-G-T-F-D-M-E-G-L-V-R-V-L-S-R-V-R-D-D-E-G-I-E-L-V-V-V-G-Y-P-M-S-D-K-G-E-E-N-R-M-T-G-V-I-D-R-F-V-A-E-L-R-E-S-F-P-G-T-L-I-E-T-F-D-E-H-R-S-S-R-T-A-M-K-I-L-A-A-S-G-S-S-R-K-K-R-N-E-K-G-R-L-D-T-A-A-A-C-L-I-L-Q-G-Y-L-D-S-H-S


### FUNCTION This basic c-type monoheme cytochrome has been found exclusively in the green photosynthetic bacteria, although its role in bacterial photosynthesis is not established It has an unusually low redox potential compared with mitochondrial cytochrome c It is reactive with cytochrome c oxidases but not with reductases ### SEQUENCE -M-S-R-F-V-S-A-A-L-V-G-A-A-L-L-V-S-G-N-A-F-A-Y-D-A-A-A-G-K-A-T-Y-D-A-S-C-A-T-C-H-K-T-G-M-M-G-A-P-K-V-G-D-K-A-A-W-A-P-R-I-A-Q-G-M-N-T-L-V-S-K-S-I-K-G-Y-K-G-T-K-G-M-M-P-A-K-G-G-N-A-K-L-T-D-A-Q-V-G-N-A-V-A-Y-M-V-G-Q-S-K


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-L-T-S-G-I-I-L-L-E-G-G-L-L-N-P-N-P-G-L-I-F-W-T-A-L-T-F-L-I-V-L-V-I-L-R-K-T-A-W-G-P-I-L-S-M-L-E-E-R-A-K-S-I-Q-S-A-I-D-R-A-H-T-A-K-D-E-A-E-A-I-L-K-K-N-R-D-L-L-A-K-A-D-A-E-A-D-K-I-I-R-E-A-K-E-V-A-D-K-L-R-A-D-L-T-E-K-A-H-D-E-S-R-K-I-I-A-S-A-K-E-E-I-E-Q-E-K-R-R-A-L-D-V-L-R-N-E-V-A-D-M-A-V-K-G-A-E-K-I-I-R-T-T-L-D-A-D-K-Q-K-A-V-V-N-D-M-I-K-E-M-A-A-S-R-N


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-S-A-I-A-S-R-R-Y-A-V-A-L-L-E-V-A-V-E-G-N-F-L-E-K-V-T-E-D-L-Q-K-I-Q-E-V-L-S-G-S-H-E-L-V-L-A-L-K-S-P-L-I-N-V-D-L-K-S-K-I-L-E-E-I-F-R-N-K-V-D-E-K-T-M-V-F-I-K-L-L-A-H-K-K-R-A-A-L-L-A-G-V-I-S-E-F-N-A-L-I-D-E-R-N-G-V-I-N-A-D-V-K-S-A-I-K-L-S-D-E-Q-A-K-E-L-V-N-S-L-S-V-R-T-G-K-K-I-R-A-K-M-R-L-D-E-N-L-I-G-G-V-T-V-K-I-G-D-T-I-I-D-G-S-I-S-H-Q-L-E-M-L-R-H-S-L-V-A-Q-P-A


### FUNCTION Catalyzes the reversible adenylation of nicotinate mononucleotide ### SEQUENCE -M-R-T-A-V-F-G-G-S-F-D-P-P-H-N-G-H-L-A-L-S-L-F-A-R-E-L-A-G-L-D-R-L-I-V-S-V-S-K-N-P-F-K-A-A-A-D-A-S-D-D-D-R-S-A-M-A-R-L-L-V-A-E-I-N-V-A-G-V-F-A-E-I-S-G-W-E-L-Q-Q-S-G-P-S-Y-T-I-D-L-L-R-H-V-E-E-R-C-P-G-D-E-L-V-L-L-V-G-E-D-S-Y-L-Q-M-P-Q-W-K-F-A-S-E-I-L-K-H-C-T-I-A-V-F-G-R-S-D-I-D-A-A-D-A-P-P-S-D-P-L-L-P-A-I-H-Y-D-F-D-M-P-V-S-A-T-K-I-R-R-L-A-A-A-G-Q-P-I-G-Q-F-V-P-S-S-I-A-Q-Y-I-A-E-H-K-L-Y-S-A


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-Y-P-G-M-L-S-E-K-R-T-N-A-L-P-R-G-E-I-A-R-G-K-S-A-V-S-R-L-F-S-Q-G-G-R-L-K-G-G-F-L-L-L-I-Y-S-A-S-R-P-V-E-Q-A-P-R-I-P-V-R-V-L-F-T-V-G-K-K-L-V-P-R-A-V-D-R-N-R-I-K-R-L-M-R-E-A-Y-R-L-E-K-N-I-L-T-R-A-L-A-F-D-A-G-K-G-D-H-Q-V-M-L-A-F-L-Y-R-A-R-A-D-A-I-P-S-L-E-R-F-R-A-E-I-R-H-M-L-K-N-L-L-S-N-R-L-P-Q-T-R-E-G-D-R-I-E


### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-F-K-E-Y-K-I-Y-K-F-F-E-Q-V-K-Q-E-T-Y-K-V-V-W-P-T-R-K-E-L-V-A-S-T-L-V-V-V-V-A-V-F-I-F-S-L-I-C-L-V-L-D-Y-S-I-H-N-I-M-Q-L-L-L-N-I-G-K


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-I-E-E-K-E-Q-T-V-G-G-F-V-L-A-G-S-A-Q-E-K-T-K-T-A-Q-V-V-A-T-G-Q-G-V-R-T-L-N-G-D-L-V-A-P-S-V-K-P-G-D-R-V-L-V-E-A-H-A-G-I-D-V-K-D-G-D-E-K-Y-I-I-V-G-E-A-N-I-L-A-I-I-E-E


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-L-K-P-L-G-D-R-I-V-V-H-F-E-E-T-E-E-K-T-A-S-G-F-V-L-A-G-A-S-H-E-A-T-K-T-A-E-V-L-A-V-G-E-G-I-R-T-L-T-G-E-L-I-A-L-S-V-A-A-G-D-K-V-L-V-E-N-G-A-G-V-N-V-K-D-G-D-D-S-V-S-I-I-R-E-A-D-I-L-A-V-L-A


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-E-V-E-E-K-E-Q-K-V-G-G-F-V-I-A-G-A-G-Q-D-A-T-K-T-A-K-V-V-A-V-G-E-G-I-R-T-L-N-G-E-L-V-A-P-S-V-K-A-G-D-T-V-L-V-E-S-H-V-G-T-E-V-K-D-G-E-E-K-Y-L-V-V-N-E-V-N-I-L-A-I-V-E


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-V-E-E-E-K-E-Q-T-V-G-G-F-V-L-A-G-A-S-K-E-R-T-Q-V-A-T-V-V-A-V-G-D-G-A-R-T-L-T-G-E-L-V-A-P-S-V-A-A-G-D-K-V-I-I-E-N-G-V-G-I-E-V-K-D-D-D-N-T-V-T-I-V-R-E-A-D-I-L-A-I-L-A


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-V-E-E-K-E-Q-K-V-G-G-F-V-I-A-G-N-G-Q-A-A-T-K-T-A-E-V-V-A-V-G-Q-G-I-R-T-L-N-G-E-L-V-S-L-S-V-K-E-G-E-K-V-L-V-E-N-H-A-G-V-E-V-K-D-G-D-E-A-Y-L-L-V-S-E-A-N-I-L-A-V-V-E


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-V-E-E-R-E-Q-K-V-G-G-F-V-I-A-G-A-G-Q-D-A-T-K-T-A-K-V-I-A-V-G-E-G-I-R-T-L-N-G-E-L-V-A-P-S-V-K-A-D-D-T-V-L-V-E-S-H-A-G-I-E-V-K-D-G-E-E-K-Y-L-V-V-N-E-T-N-I-L-A-I-V-E


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-L-K-P-L-G-D-R-V-V-L-K-V-E-E-K-E-Q-K-V-G-G-F-V-I-A-G-A-G-Q-D-A-T-K-T-A-K-V-V-A-A-G-D-G-I-R-T-L-N-G-E-L-V-A-P-S-V-K-A-G-D-T-V-L-V-E-S-H-A-G-I-E-V-K-D-G-E-E-K-Y-L-V-V-N-E-A-N-I-L-A-I-V-E


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-R-I-K-P-L-G-D-R-V-V-I-K-R-L-E-A-E-E-K-T-K-S-G-I-V-L-P-G-S-A-K-E-K-P-Q-E-A-E-I-V-A-V-G-P-G-G-L-V-D-G-K-E-V-N-M-E-V-K-V-G-D-R-V-L-F-S-Q-Y-A-G-N-E-V-K-I-D-G-E-E-Y-I-I-L-R-Q-N-D-I-L-A-I-V-E


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-I-V-A-V-P-N-S-G-A-S-R-I-N-Q-S-G-V-E-A-L-R-E-F-P-N-F-P-I-G-G-I-L-F-K-D-I-A-P-M-L-A-G-R-G-A-L-G-E-V-V-S-T-V-A-S-Q-V-S-G-T-E-I-D-A-I-L-A-V-D-A-R-G-F-I-L-G-A-S-L-A-D-R-L-G-C-G-F-I-M-V-R-K-P-G-K-L-P-G-D-V-L-S-F-E-Y-S-C-E-Y-C-S-G-T-L-E-V-T-A-G-L-I-G-D-G-L-R-C-L-I-A-D-D-L-L-A-T-G-G-T-A-R-A-T-G-N-F-V-K-S-Q-G-G-E-I-A-G-Y-A-F-I-L-E-I-E-V-L-K-G-R-R-Q-L-D-D-A-P-V-I-S-A-M-T-C


### FUNCTION May protect the nitrogenase Fe-Mo protein from oxidative damage ### SEQUENCE -M-C-R-C-S-A-D-S-S-P-V-D-V-K-D-I-L-N-R-L-K-S-L-S-A-A-E-E-F-F-E-A-L-G-V-P-Y-D-P-K-V-L-D-V-S-R-L-H-I-M-K-R-M-G-Q-Y-L-A-A-E-D-F-S-H-L-P-D-R-V-I-A-A-R-A-R-A-I-L-E-R-A-Y-C-D-F-A-T-S-A-P-L-S-H-R-V-F-K-V-L-K-D-H-N-P-N-R-P-V-T-P-G-R-T-V-V-P-L-D-S-F-L-K-P-F-E-K-K


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-K-D-T-I-R-T-E-G-V-V-T-E-A-L-P-N-A-T-F-R-V-K-L-D-S-G-P-E-I-L-A-Y-I-S-G-K-M-R-M-H-Y-I-R-I-L-P-G-D-R-V-V-V-E-I-T-P-Y-D-P-T-R-G-R-I-V-Y-R-K


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-T-E-L-A-N-I-P-E-L-L-A-S-R-I-R-D-V-A-D-Y-P-E-P-G-V-M-F-K-D-I-T-P-L-L-A-D-P-V-A-F-T-A-L-T-D-T-L-A-A-G-R-R-R-H-P-R-T-K-V-V-G-L-E-A-R-G-F-I-L-G-A-P-V-A-V-R-A-G-L-G-F-I-P-V-R-K-A-G-K-L-P-G-A-T-L-S-Q-A-Y-D-L-E-Y-G-S-A-E-I-E-V-H-A-E-D-L-A-A-G-D-R-V-L-I-V-D-D-V-L-A-T-G-G-T-A-E-A-A-I-Q-L-I-R-R-A-G-A-E-V-C-G-L-A-V-L-M-E-L-G-F-L-G-G-R-A-R-L-E-P-I-L-D-G-A-P-L-E-A-L-L-Q-V


### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-T-V-D-H-T-R-M-N-A-P-A-V-R-V-A-K-T-M-K-T-P-H-G-D-T-I-T-V-F-D-L-R-F-C-I-P-N-K-Q-V-M-P-E-K-G-I-H-T-L-E-H-L-F-A-G-F-M-R-N-H-L-N-G-E-G-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-E-P-A-E-V-R-V-A-D-A-W-K-A-A-M-A-D-V-L-K-V-K-D-Q-S-Q-I-P-E-L-N-I-Y-Q-C-G-T-Y-H-M-H-S-L-T-E-A-Q-D-I-A-H-H-I-L-D-S-D-V-L-V-N-K-N-D-E-L-A-L-P-E-E-K-L-T-E-L-K-V


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-K-I-R-P-L-H-D-R-I-V-V-R-R-K-E-E-E-T-A-T-A-G-G-I-I-L-P-G-A-A-A-E-K-P-N-Q-G-V-V-I-S-V-G-T-G-R-I-L-D-N-G-S-V-Q-A-L-A-V-N-E-G-D-V-V-V-F-G-K-Y-S-G-Q-N-T-I-D-I-D-G-E-E-L-L-I-L-N-E-S-D-I-Y-G-V-L-E-A


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-K-K-K-A-E-D-K-Q-P-I-I-K-D-E-A-V-E-E-P-K-S-D-S-K-V-N-A-L-S-A-K-I-A-E-L-Q-Q-Q-L-D-D-S-Q-N-D-Y-L-R-A-Q-A-E-I-Q-N-M-Q-K-R-S-Q-K-E-Q-S-A-L-A-K-Y-G-A-Q-R-L-A-K-E-V-V-P-V-M-D-D-L-K-R-A-L-Q-V-Q-V-D-N-D-S-G-Q-Q-L-K-T-G-I-E-M-V-Y-K-H-L-E-K-A-L-N-D-N-D-I-K-E-I-D-A-D-G-V-A-F-D-P-E-L-H-Q-A-V-Q-T-V-P-A-D-D-D-H-P-A-D-T-V-V-Q-V-L-Q-S-G-Y-K-L-A-D-R-V-L-R-P-A-M-V-V-V-A-Q


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-A-G-G-G-R-I-P-L-W-I-V-A-T-V-A-G-T-G-V-L-V-V-V-G-L-F-F-Y-G-A-Y-A-G-L-G-S-S-L


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-P-T-R-S-T-N-P-N-K-Q-P-V-E-L-N-R-T-S-L-F-L-G-L-L-L-V-F-V-L-G-I-L-F-S-S-Y-F-F-N


### FUNCTION Component of the type IV secretion system VirB/VirD4 which could be a major virulence determinant for subversion of human endothelial cell  function VirB2 seems to constitute the major pilus component ### SEQUENCE -M-T-E-T-I-S-R-N-I-I-F-I-V-I-V-L-L-L-T-A-L-V-V-S-N-P-S-Y-A-A-N-S-A-S-S-L-G-N-V-D-S-V-L-Q-N-I-V-T-M-M-T-G-T-T-A-K-L-I-A-I-I-C-V-A-A-V-G-I-G-W-M-S-G-F-I-D-L-R-K-A-A-Y-C-I-L-G-I-G-I-V-F-G-A-P-T-L-V-S-T-L-M-G-S-S


### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-S-K-E-V-I-V-E-S-F-E-L-D-H-T-I-V-K-A-P-Y-V-R-L-I-G-E-E-S-G-P-K-G-D-V-I-S-N-F-D-I-R-L-V-Q-P-N-E-D-S-I-P-T-A-G-L-H-T-I-E-H-L-L-A-M-L-I-R-K-R-I-D-G-M-I-D-C-S-P-F-G-C-R-T-G-F-H-M-I-M-W-G-R-H-T-P-S-E-I-A-Q-V-I-K-S-C-L-E-E-I-A-E-T-T-T-W-E-D-V-P-G-T-T-I-E-S-C-G-N-Y-K-D-H-S-L-F-S-A-K-E-W-A-K-L-I-L-K-Q-G-I-S-D-N-A-F-E-R-H-V-I


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-S-Q-L-V-R-K-G-R-E-K-L-V-V-K-G-K-S-P-A-L-K-E-S-P-Q-K-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-N-G-I-E-V-T-S-Y-I-P-G-V-G-H-N-L-Q-E-H-S-V-V-M-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-S-V-G-V-A-G-R-K-Q-S-R-S-K-Y-G-A-K-R-P-S


### FUNCTION One of the proteins required for the normal export of preproteins out of the cell cytoplasm It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state It specifically binds to its receptor SecA Also required for the secretion of HasA via an ABC transporter system ### SEQUENCE -M-S-E-Q-N-S-T-E-M-A-F-Q-I-Q-R-I-Y-T-K-D-I-S-F-E-A-P-N-A-P-Q-V-F-Q-Q-E-W-Q-P-E-V-K-L-D-L-D-T-A-S-S-Q-L-A-D-E-V-Y-E-V-V-L-R-V-T-V-T-A-T-L-G-E-E-T-A-F-L-C-E-V-Q-Q-A-G-I-F-S-V-A-G-I-E-G-T-Q-L-A-H-C-L-G-A-Y-C-P-N-I-L-F-P-Y-A-R-E-C-I-T-S-L-V-S-R-G-T-F-P-Q-L-N-L-A-P-V-N-F-D-A-L-F-M-N-Y-L-Q-Q-Q-A-E-G-E-G-A-A-P-H-Q-D-A


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-I-E-A-Q-V-G-K-R-Y-A-E-A-I-Y-G-I-A-E-A-N-N-K-V-K-E-L-Y-D-S-L-N-I-V-M-E-L-Y-K-G-D-K-E-F-K-N-L-V-D-H-P-L-V-K-K-E-E-K-K-E-F-I-N-K-V-F-S-E-F-E-K-F-S-L-D-I-L-C-Y-L-V-E-K-N-R-L-S-Y-I-R-G-V-V-A-E-Y-L-K-I-Y-Y-T-K-N-R-I-V-D-V-E-A-T-F-A-I-E-P-S-E-K-Q-K-A-K-L-I-E-K-L-E-K-K-T-G-K-K-V-N-L-V-I-K-I-N-K-A-I-I-A-G-G-I-I-K-I-G-D-E-I-I-D-G-S-V-R-R-Q-L-D-T-V-A-R-G


### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-F-K-E-Y-K-I-Y-K-F-F-E-Q-V-K-Q-E-A-Y-K-V-V-W-P-T-K-K-E-L-T-A-S-T-L-V-V-I-V-A-V-F-V-F-S-L-I-C-L-V-L-D-Y-G-I-H-N-I-I-Q-I-L-L-N-I-G-K


### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-F-K-E-Y-K-I-Y-K-F-F-E-Q-V-K-Q-E-T-Y-K-V-V-W-P-T-R-K-E-L-V-A-S-T-L-V-V-V-V-A-V-F-I-F-S-P-I-C-L-V-L-D-Y-S-I-H-N-I-M-Q-L-L-L-N-I-G-K


### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-F-K-E-Y-K-I-Y-K-F-F-E-Q-V-K-Q-E-T-Y-K-V-V-W-P-T-R-K-E-L-V-A-S-T-L-V-V-V-V-A-V-F-I-F-S-L-T-C-L-V-L-D-Y-S-I-H-N-I-M-Q-L-L-L-N-I-G-K


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-Q-K-K-H-P-Q-G-N-I-A-Q-N-K-K-A-L-H-D-Y-F-I-E-Q-K-F-E-A-G-L-A-L-S-G-W-E-V-K-S-L-R-A-G-K-A-Q-L-V-D-S-Y-V-L-L-K-D-G-E-A-W-L-M-G-S-H-I-T-P-L-K-T-A-S-T-H-V-I-A-D-P-T-R-T-R-K-L-L-L-H-K-R-E-L-G-R-L-F-G-S-V-Q-Q-K-G-Y-A-C-V-A-L-S-L-Y-W-K-K-H-L-I-K-C-E-I-A-L-A-K-G-K-K-E-Y-D-K-R-D-T-E-K-A-R-D-S-D-R-E-I-Q-R-A-I-R-S-K-G-K-E-D


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-S-N-D-D-I-V-S-R-I-A-S-M-T-A-L-E-L-S-D-L-V-G-L-L-E-Q-R-F-N-I-S-R-I-A-P-A-P-C-Q-P-G-S-N-A-V-E-A-E-Q-D-R-R-D-R-K-V-F-L-T-H-S-G-S-N-K-I-A-V-I-R-A-V-R-D-V-T-K-L-G-L-K-E-S-K-G-L-V-D-S-A-P-S-L-V-A-E-G-L-S-A-D-E-A-E-D-I-R-A-K-V-E-A-A-G-A-K-A-E-V-R


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-S-K-I-R-P-L-G-D-R-V-V-V-K-R-S-E-D-E-T-K-T-P-C-G-I-V-I-P-D-S-A-A-E-K-Q-D-Q-G-T-V-V-A-L-G-P-G-K-K-D-S-E-G-A-R-V-P-M-E-V-R-L-G-D-R-V-L-F-G-K-Y-A-G-Q-S-I-K-V-D-D-E-D-L-M-V-M-R-E-E-D-I-V-A-V-I-E


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-A-K-K-Q-M-A-M-I-E-K-Y-A-D-K-R-Q-E-L-K-A-A-G-D-R-T-A-L-A-K-L-P-R-D-S-N-P-N-R-L-R-L-R-D-Q-T-D-G-R-P-R-G-Y-M-R-K-F-G-M-S-R-I-K-F-R-E-L-A-H-Q-G-L-I-P-G-V-K-K-A-S-W


### FUNCTION Major structure protein of the hrp pilus, which is a component of the type III secretion system ### SEQUENCE -M-G-L-S-N-A-A-S-L-A-S-M-Q-T-L-D-K-A-M-A-S-A-T-A-M-T-T-A-A-Q-A-Q-K-V-Q-T-D-A-I-S-S-I-T-D-G-Q-M-D-S-A-S-K-A-M-N-S-G-Q-K-A-A-K-A-I-Q-F


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-V-A-I-M-T-E-T-V-A-I-A-N-A-A-A-E-R-Q-N-A-T-K-I-V-G-L-T-M-R-I-G-A-I-S-G-V-V-P-E-A-L-S-F-A-F-E-A-V-A-G-G-T-L-A-E-Q-A-Q-L-I-I-E-T-V-P-V-T-C-Y-C-A-Q-C-D-R-P-F-T-P-P-D-L-F-Y-E-C-P-L-C-S-S-L-S-Q-H-I-L-S-G-K-E-V-E-L-K-S-L-E-V-I


### FUNCTION Required for disulfide bond formation in some proteins ### SEQUENCE -M-T-I-I-R-K-Y-H-I-A-I-A-W-T-I-A-T-S-A-M-L-I-S-L-I-F-S-E-W-M-K-L-P-P-C-D-L-C-W-Y-Q-R-M-A-M-Y-P-L-V-L-I-L-G-I-G-M-Y-R-K-D-S-N-V-S-I-Y-A-F-P-F-A-C-I-G-L-I-I-S-V-Y-Q-I-T-I-Q-A-F-P-T-S-E-M-K-I-C-S-V-G-V-S-C-T-E-N-Y-L-N-L-F-G-F-I-S-I-P-M-L-S-F-V-G-F-L-A-I-I-I-L-L-Y-I-N-Q-I-K-R-Q-K-N-K


### FUNCTION May act as a membrane anchor for the tetrachloroethene reductive dehalogenase PceA ### SEQUENCE -M-N-I-Y-D-V-L-I-W-M-A-L-G-M-T-A-L-L-I-Q-Y-G-I-W-R-Y-L-K-G-K-G-K-D-T-I-P-L-Q-I-C-G-F-L-A-N-F-F-F-I-F-A-L-A-W-G-Y-S-S-F-S-E-R-E-Y-Q-A-I-G-M-G-F-I-F-F-G-G-T-A-L-I-P-A-I-I-T-Y-R-L-A-N-H-P-A-K-K-I-R-E-S-S-D-S-I-S-A


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-E-D-I-E-I-D-L-D-D-L-E-R-R-M-K-G-A-M-D-S-L-R-A-E-F-A-S-L-R-T-G-R-A-S-A-S-M-V-E-P-V-Q-V-E-A-Y-G-Q-M-T-P-I-N-Q-V-G-T-V-N-V-P-E-P-R-M-V-T-I-N-V-W-D-K-G-M-V-G-K-V-E-K-A-I-R-E-S-G-L-G-I-N-P-Q-T-N-G-T-I-I-M-L-P-I-P-E-L-N-E-E-R-R-R-E-L-T-K-V-A-A-Q-Y-A-E-H-A-R-V-A-I-R-N-V-R-R-D-G-M-D-Q-I-K-K-G-K-A-N-G-M-P-E-D-D-Q-K-F-W-E-T-A-V-Q-E-L-T-D-K-S-I-G-N-V-D-Q-A-L-E-A-K-Q-A-E-I-M-Q-V


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-S-D-I-Q-T-L-S-F-E-E-A-M-R-E-L-E-A-T-V-G-K-L-E-T-G-E-A-T-L-E-D-S-I-A-L-Y-E-R-G-A-A-L-R-A-H-C-E-T-R-L-R-E-A-E-E-R-V-E-K-I-T-L-A-A-N-G-Q-P-S-G-T-E-P-A-E-G-L


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-E-N-N-E-P-V-V-E-T-P-E-A-Q-N-D-L-P-E-V-E-R-L-K-G-E-V-E-F-L-K-A-E-L-E-A-S-K-N-K-F-L-R-L-Y-A-D-F-E-N-Y-K-K-R-M-V-Q-E-L-E-A-A-Q-R-N-G-K-F-D-A-V-R-A-L-L-G-T-L-D-D-L-E-R-A-L-G-F-A-S-V-K-P-E-D-L-I-P-G-V-R-S-V-L-E-N-F-T-R-S-L-K-S-L-G-V-E-A-V-P-G-V-G-A-E-F-D-P-R-Y-H-E-A-I-G-A-V-E-G-E-E-G-K-V-M-H-V-Y-Q-Q-G-F-K-Y-G-D-L-L-V-R-P-A-R-V-V-V-G-S-G-A-K-P-E-E-A-E-A


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-A-I-S-I-N-V-S-T-V-K-P-L-G-D-R-V-F-V-K-V-S-A-S-E-E-K-T-A-G-G-I-L-L-P-D-T-A-K-E-K-P-Q-I-G-E-I-V-T-V-G-P-G-K-R-N-D-D-G-S-R-S-E-P-E-V-K-V-G-D-K-V-L-Y-S-K-Y-A-G-T-D-I-K-L-G-G-E-D-Y-V-L-L-S-E-K-D-I-L-A-V-V-D


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-D-K-E-K-D-A-V-I-V-D-E-T-E-H-V-D-V-D-S-K-E-S-K-K-E-K-K-T-K-Q-Q-Q-K-I-E-F-L-E-A-E-V-K-E-L-N-D-K-Y-L-R-T-L-A-E-A-E-N-F-K-K-R-I-Q-A-E-K-I-M-D-R-K-Y-A-A-S-S-F-A-T-E-L-L-V-P-Y-E-Q-F-S-K-I-V-D-F-P-S-D-N-E-L-L-N-N-F-L-I-G-F-K-M-I-R-D-Q-F-K-S-V-L-E-N-E-G-V-V-E-I-K-A-L-G-E-V-F-D-A-K-V-H-H-A-I-E-K-E-S-N-K-D-K-P-N-G-T-V-L-E-V-L-Q-N-G-Y-L-F-K-D-R-I-L-R-P-A-M-V-K-I-N-E-W-S-E-D-N-G-E-D-K


### FUNCTION Binds to actin and affects the structure of the cytoskeleton At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations ### SEQUENCE -M-S-W-Q-A-Y-V-D-E-H-L-M-C-E-I-D-G-H-H-L-T-A-A-A-I-L-G-H-D-G-S-V-W-A-Q-S-S-S-F-P-Q-F-K-S-E-E-I-T-N-I-M-N-D-F-N-E-P-G-S-L-A-P-T-G-L-Y-L-G-S-T-K-Y-M-V-I-Q-G-E-P-G-A-V-I-R-G-K-K-G-S-G-G-V-T-V-K-K-T-N-Q-A-L-I-F-G-I-Y-E-E-P-M-T-P-G-Q-C-N-M-V-V-E-R-L-G-D-Y-L-I-E-Q-G-M


### FUNCTION Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites ### SEQUENCE -M-E-E-K-W-K-L-S-K-K-D-T-T-A-S-S-S-S-S-K-S-K-F-S-R-S-F-S-T-S-A-S-S-T-K-S-P-I-F-V-R-S-S-S-T-K-C-S-V-P-S-S-S-S-S-S-S-S-S-S-S-I-S-R-S-F-S-R-K-E-R-R-S-S-S-S-S-S-S-S-I-T-Q-K-Y-S-S-L-A-K-E-Q-K-A-R-F-Y-I-M-R-R-C-V-A-M-L-V-C-W-H-K-H-G-D-S


### FUNCTION Mediates the uptake of pyruvate into mitochondria ### SEQUENCE -M-A-T-S-K-L-Q-A-L-W-N-H-P-A-G-P-K-T-I-H-F-W-A-P-T-F-K-W-G-I-S-I-A-N-I-A-D-F-Q-K-P-P-E-N-I-S-Y-L-Q-Q-I-A-V-T-C-T-G-M-I-W-C-R-C-S-T-I-I-T-P-K-N-W-N-L-F-S-V-N-V-A-M-A-A-T-G-I-Y-Q-L-T-R-K-I-K-Y-D-Y-V-S-E-A-E-A-A-V-E-I-E-G


### FUNCTION Involved in the assembly of mitochondrial iron-sulfur proteins Probably involved in the binding of an intermediate of Fe/S cluster assembly ### SEQUENCE -M-R-K-Q-V-L-A-L-S-D-T-A-A-A-R-I-R-Q-L-L-Q-H-Q-Q-K-P-F-L-R-L-A-V-E-A-K-G-C-N-G-L-S-Y-V-L-N-Y-A-Q-E-K-G-K-F-D-E-V-V-E-E-K-G-V-K-I-L-V-D-P-K-A-V-M-H-V-I-G-T-E-M-D-F-V-D-D-K-L-R-S-E-F-V-F-V-N-P-N-A-T-K-C-G-C-G-E-S-F-T-T-T


### FUNCTION Subunit of the oligosaccharyl transferase  All subunits are required for a maximal enzyme activity ### SEQUENCE -M-F-D-D-Q-D-L-G-F-F-A-N-F-L-G-I-F-I-F-I-M-V-I-A-Y-H-F-V-V-A-E-P-K-F-E


### FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase Reduces low molecular weight disulfides and proteins ### SEQUENCE -M-M-Q-E-L-G-L-Q-R-F-S-N-D-V-V-R-L-D-L-T-P-P-S-Q-T-S-S-T-S-L-S-I-D-E-E-E-S-T-E-A-K-I-R-R-L-I-S-E-H-P-V-I-I-F-S-R-S-S-C-C-M-C-H-V-M-K-R-L-L-A-T-I-G-V-I-P-T-V-I-E-L-D-D-H-E-V-S-S-L-P-T-A-L-Q-D-E-Y-S-G-G-V-S-V-V-G-P-P-P-A-V-F-I-G-R-E-C-V-G-G-L-E-S-L-V-A-L-H-L-S-G-Q-L-V-P-K-L-V-Q-V-G-A-L-W-V


### FUNCTION Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane ### SEQUENCE -M-E-T-T-K-S-N-S-S-E-S-D-V-N-A-K-W-D-A-C-L-D-L-T-A-R-R-F-V-Y-S-S-L-G-G-A-F-A-G-L-L-F-F-R-S-P-V-T-R-W-A-S-I-A-F-G-A-G-I-G-I-G-S-A-Y-T-D-C-S-R-V-F-D-A-S-S-S-T-S-A-T-L-L-A-A-P-K-S-T-E-T-S-V-S-Q-A-A-E-E


### FUNCTION Elicitor of plant defense ### SEQUENCE -M-E-N-L-R-N-G-E-D-N-G-S-L-I-P-F-T-F-F-D-Q-S-S-V-T-I-P-L-L-K-C-S-G-L-E-S-S-S-S-S-S-S-S-C-D-L-S-S-S-H-S-E-E-D-E-S-I-D-I-K-E-E-E-E-E-E-E-E-D-G-M-T-I-E-I-K-A-R-G-K-N-K-T-K-P-T-P-S-S-G-K-G-G-K-H-N


### FUNCTION Variable subunit of the ferredoxin-thioredoxin reductase , which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin ### SEQUENCE -M-T-N-S-Y-A-L-S-P-A-I-I-A-A-V-R-P-P-A-S-Q-D-Y-L-V-A-A-S-L-S-G-R-K-S-I-N-S-S-S-S-S-I-F-V-P-I-S-L-S-T-S-Y-G-R-S-K-C-A-F-S-I-S-R-K-N-P-K-S-T-I-R-C-D-I-A-V-K-S-A-A-S-V-D-A-D-A-D-L-S-S-S-T-S-L-E-T-E-E-D-E-K-A-K-E-K-I-G-A-R-V-R-V-T-V-P-L-K-V-Y-H-V-V-R-V-P-E-V-E-L-M-G-M-E-G-F-I-K-D-Y-V-V-L-W-K-G-K-K-I-S-A-N-L-P-F-K-V-Q-F-V-K-E-I-E-G-R-G-P-V-K-F-F-T-H-L-K-E-D-E-F-E-L-I-D-P


### FUNCTION Probable thiol-disulfide oxidoreductase that may participate in various redox reactions ### SEQUENCE -M-R-K-Q-E-S-E-G-A-N-L-E-F-E-S-K-S-N-D-N-G-N-V-K-I-A-P-N-D-Q-S-F-L-T-I-L-D-D-I-K-S-S-K-S-P-A-V-I-N-Y-G-A-S-W-C-G-V-C-S-Q-I-L-P-A-F-R-K-L-S-N-S-F-S-K-L-K-F-V-Y-A-D-I-D-E-C-P-E-T-T-R-H-I-R-Y-T-P-T-F-Q-F-Y-R-D-G-E-K-V-D-E-M-F-G-A-G-E-Q-R-L-H-D-R-L-W-L-H-S


### FUNCTION May regulate transcription elongation by RNA polymerase II May enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex ### SEQUENCE -M-G-E-A-P-A-Q-I-P-T-S-F-G-H-E-L-R-A-C-L-R-C-R-L-V-K-T-Y-D-Q-F-R-D-S-G-C-E-N-C-P-F-F-K-I-E-D-D-H-E-R-I-V-D-V-T-T-P-N-F-N-G-I-I-S-M-M-D-P-R-R-S-W-A-A-R-W-L-R-I-G-K-F-A-P-G-C-Y-T-L-A-V-S-E-A-L-P-E-E-M-Q-F-I-C-Q-Q-A-R-V-Q-Y-V-P-P-K-R-I


### FUNCTION Elicitor of plant defense ### SEQUENCE -M-Q-Q-E-R-D-H-K-R-D-C-C-K-L-M-P-Q-T-V-K-A-F-F-K-C-L-R-F-R-R-S-S-S-S-S-S-D-M-V-K-A-R-A-R-N-E-E-K-E-E-P-S-S-I-E-T-S-T-R-S-L-N-V-M-R-K-G-I-R-K-Q-P-V-S-S-G-K-R-G-G-V-N-D-Y-D-M


### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase ### SEQUENCE -M-G-G-G-G-H-G-G-G-I-T-Y-K-G-V-T-V-H-T-P-K-T-W-H-T-V-T-G-K-G-L-C-A-V-M-W-F-W-I-L-Y-R-A-K-Q-D-G-P-V-V-M-G-W-R-H-P-W-D-G-H-G-D-H-G-H-G-D-H-H


### FUNCTION  Extracellular signal peptide that regulates cell fate ### SEQUENCE -M-R-R-H-D-I-I-I-K-L-L-L-L-M-C-L-L-L-S-R-F-V-T-R-E-C-Q-E-V-H-F-K-I-G-P-A-K-I-I-A-K-P-N-N-A-R-V-M-P-T-W-G-E-E-K-K-W-H-K-H-P-S-G-P-N-P-T-G-N-R-H-P-P-V-K-H


### FUNCTION Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites ### SEQUENCE -M-D-D-E-N-L-W-K-V-V-K-K-D-S-I-F-E-T-T-H-F-S-S-K-P-V-F-T-R-S-F-S-T-K-T-S-S-S-S-S-K-P-V-F-T-R-S-F-S-T-K-P-T-S-Y-S-S-S-E-P-I-F-R-R-S-F-S-A-K-P-T-S-S-K-S-P-F-L-S-R-S-G-S-T-K-C-P-V-D-T-S-S-T-S-K-C-S-I-S-R-S-L-S-Q-K-G-A-S-V-T-R-K-C-R-N-M-A-K-E-H-K-S-R-F-Y-I-M-K-R-C-V-L-M-L-V-C-W-H-K-H-A-C-D-S


### FUNCTION Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions ### SEQUENCE -M-G-K-R-K-S-R-A-K-P-A-P-T-K-R-M-D-K-L-D-T-I-F-S-C-P-F-C-N-H-G-S-S-V-E-C-I-I-D-M-K-H-L-I-G-K-A-A-C-R-I-C-E-E-S-F-S-T-T-I-T-A-L-T-E-A-I-D-I-Y-S-E-W-I-D-E-C-E-R-V-N-T-A-E-D-D-V-V-Q-E-E-E-E-E-V-E-E-E-E-E-E-E-E-E-E-D-D-E-D-D-H-V-S-V-K-R-K-Y-N-F


### FUNCTION Acts redundantly with SPR1 in maintaining the cortical microtubules organization essential for anisotropic cell growth ### SEQUENCE -M-S-R-G-G-S-F-G-G-G-Q-S-S-L-G-Y-L-F-G-S-D-N-E-I-P-K-T-P-A-P-P-V-A-P-K-P-A-P-P-Y-G-V-D-S-T-E-E-D-H-E-A-D-Q-K-P-K-I-S-N-N-N-Y-Q-R-V-Q-G-Q-N-S-G-N-F-V-T-D-R-P-T-T-K-V-K-S-V-P-G-G-G-S-S-L-G-Y-L-F-G-D-K


### FUNCTION Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions ### SEQUENCE -M-G-K-R-K-S-A-A-K-P-P-P-K-K-R-M-D-K-L-D-T-V-F-S-C-P-F-C-N-H-G-S-S-V-E-C-R-I-D-M-K-N-L-I-G-E-A-S-C-R-I-C-Q-E-N-F-S-T-T-V-N-A-L-T-E-P-I-D-I-Y-S-E-W-I-D-E-C-E-R-V-N-N-V-E-D-D-D-G-A


### FUNCTION Involved in calcium binding and microtubule stabilization ### SEQUENCE -M-L-V-Y-Q-D-K-L-S-G-D-E-L-L-S-D-S-F-P-Y-R-E-L-E-N-G-V-L-W-E-V-D-G-H-W-V-V-Q-G-A-V-D-V-D-I-G-A-N-P-S-A-E-G-G-G-D-D-E-G-V-D-D-Q-A-V-K-V-V-D-I-V-D-T-F-R-L-Q-E-Q-P-A-F-D-K-K-Q-F-I-S-H-M-K-R-Y-I-K-N-L-S-A-K-L-E-G-D-D-L-D-V-F-K-K-N-V-E-S-A-T-K-Y-L-L-S-K-L-K-D-L-Q-F-F-V-G-E-S-M-H-D-D-G-G-V-V-F-A-Y-Y-K-E-G-A-A-D-P-T-F-L-Y-F-A-H-G-L-K-E-V-K-C


### FUNCTION Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans Host outer membrane disruption is possibly due to local fusion between the inner and outer membrane performed by the spanin complex ### SEQUENCE -M-R-T-K-I-F-A-A-G-T-V-L-T-C-L-M-L-C-A-G-C-T-S-A-P-P-A-P-T-P-V-I-V-P-N-A-C-P-K-V-S-L-C-P-M-P-G-S-D-P-Q-T-N-G-D-L-S-A-D-I-R-Q-L-E-N-A-L-A-R-C-A-S-Q-V-K-M-I-K-H-C-Q-D-E-N-D-A-Q-T-R-Q-P-A-Q-G-A-D


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-T-R-S-L-K-K-N-P-F-V-A-N-H-L-L-R-K-I-N-K-L-N-T-K-A-E-K-D-I-I-L-T-W-S-R-A-S-T-I-I-P-T-M-I-G-H-T-I-A-I-H-N-G-K-E-H-L-P-I-Y-I-T-D-R-M-V-G-H-K-L-G-E-F-S-P-T-L-N-F-R-G-H-A-K-N-D-N-R-S-R-R


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-Q-S-N-P-N-E-Q-T-V-E-L-N-R-T-S-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N


### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-N-G-I-K-Y-A-V-F-T-D-K-S-I-R-L-L-G-K-N-Q-Y-T-F-N-V-E-S-G-S-T-R-T-E-I-K-H-W-V-E-L-F-F-D-V-K-V-I-A-M-N-S-H-R-L-P-V-K-G-R-R-V-R-P-I-M-G-H-T-M-H-Y-R-R-M-I-I-T-L-Q-P-G-Y-S-I-P-P-L-R-K-K-R-T


### FUNCTION This protein binds to 23S rRNA ### SEQUENCE -M-S-T-Y-A-I-I-D-L-G-G-K-Q-L-R-V-E-P-G-R-F-Y-D-A-H-L-F-S-S-F-K-S-L-L-S-E-S-N-T-K-I-I-I-F-R-V-L-M-I-S-H-G-T-E-V-Q-F-G-Y-P-W-L-K-N-A-S-V-K-A-R-I-L-H-K-K-Q-N-D-K-M-L-I-Y-K-M-R-S-K-K-K-T-R-K-K-F-G-H-R-Q-K-I-A-R-F-I-V-D-A-I-Q-Y-N-G-Q-T-F-T-T-N-L-K


### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-D-K-V-K-S-P-L-L-T-E-K-S-I-R-L-L-Q-K-N-Q-Y-T-F-Q-V-N-S-D-V-N-K-T-E-F-K-K-W-I-E-I-F-F-K-V-K-V-M-S-I-N-S-C-R-P-P-R-K-K-K-R-I-G-L-I-S-G-Y-T-V-R-Y-K-K-I-I-V-T-L-K-S-G-D-S-I-P-L-F-S-I


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-I-K-K-G-P-F-V-A-D-H-L-I-K-K-I-E-N-L-N-A-K-G-E-K-K-V-I-I-T-W-S-R-A-S-T-I-V-P-M-M-I-G-H-T-I-A-V-H-N-G-R-E-H-L-P-V-F-V-T-D-R-M-V-G-Q-K-L-G-E-F-S-P-T-R-T-F-R-G-H-V-K-S-D-K-K-S-R-R


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-I-N-N-T-N-S-N-I-S-I-K-A-V-G-K-K-I-R-I-S-P-H-K-M-R-K-V-I-D-Q-I-R-G-R-S-Y-E-Q-A-L-M-I-L-E-F-M-P-Y-K-A-C-N-Y-V-L-K-L-L-S-S-V-A-A-N-A-N-H-N-F-G-L-N-K-S-D-L-F-I-E-K-I-I-A-D-G-G-P-K-L-K-R-F-Q-P-R-A-Q-G-R-G-Y-P-I-L-K-P-T-C-N-L-M-I-V-V-K-V-K-S


### FUNCTION Binds to 23S rRNA ### SEQUENCE -M-I-Q-P-Q-S-Y-L-N-V-A-D-N-S-G-A-R-K-I-M-C-I-R-I-L-G-G-S-N-K-K-Y-G-H-I-G-D-T-I-I-G-V-V-K-E-A-I-P-N-M-T-L-K-K-S-E-V-V-R-A-V-I-V-R-T-C-K-E-L-K-R-K-N-G-T-I-L-R-F-D-E-N-A-A-V-I-I-N-Q-E-G-N-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-A-N-F-T-K-I-V-S-L-A-P-E-V-L


### FUNCTION Binds 5S rRNA, forms part of the central protuberance of the 50S subunit ### SEQUENCE -M-V-Q-R-L-K-S-I-Y-L-N-N-V-I-P-K-L-N-E-E-A-K-Y-K-N-V-H-Q-I-P-R-L-K-K-I-V-I-N-C-G-I-G-E-A-S-Q-N-A-K-T-L-E-Y-T-I-R-D-L-S-I-I-A-G-Q-R-P-L-V-K-R-A-K-K-A-I-A-S-F-Q-L-R-K-K-M-P-V-G-V-S-V-T-L-R-G-D-A-M-Y-A-F-L-D-R-L-I-N-L-A-L-P-R-I-R-D-F-Q-G-L-N-R-K-S-F-D-G-H-G-N-F-H-L-G-L-K-E-Q-L-M-F-P-E-I-D-Y-D-K-I-D-K-L-R-G-M-D-I-C-I-V-T-T-C-T-N-D-N-E-C-F-Q-F-L-S-A-L-G-M-P-F-Q-T-V-S-S-K-K-L


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-K-K-Q-N-L-I-E-M-E-G-I-V-T-E-S-L-P-N-A-M-F-R-V-S-L-D-N-G-C-Q-V-L-A-H-I-S-G-K-I-R-R-N-Y-I-R-I-L-P-G-D-K-V-K-V-E-L-S-P-Y-D-L-T-K-G-R-I-T-Y-R-L-R-M-K-T-T-N-G


### FUNCTION Essential for the assembly of the photosystem I  complex May act as a chaperone-like factor to guide the assembly of the PSI subunits ### SEQUENCE -M-P-R-S-Q-R-N-D-N-F-I-D-K-T-F-T-V-V-A-D-I-L-L-R-V-I-P-T-T-R-R-E-K-E-A-F-S-Y-Y-R-D-G-M-S-A-Q-S-E-G-E-Y-A-E-A-L-Q-N-Y-Y-E-A-M-R-L-E-I-D-P-Y-D-R-S-Y-I-L-Y-N-I-G-L-I-H-T-S-N-G-Q-H-T-K-A-L-E-Y-Y-L-Q-A-L-E-R-N-P-A-L-P-Q-A-F-N-N-M-A-V-I-C-H-Y-R-G-E-Q-A-I-Q-Q-G-D-P-E-N-A-E-A-W-F-D-Q-A-A-D-Y-W-K-Q-G-I-A-L-A-P-S-N-Y-I-E-A-Q-N-W-L-K-I-T-G-R-L-K-A


### FUNCTION Controls the interaction of photosystem II  cores with the light-harvesting antenna ### SEQUENCE -M-I-L-A-F-Q-L-S-V-F-A-L-V-A-I-S-F-L-L-V-V-G-V-P-V-V-L-A-S-P-D-G-W-S-T-S-K-N-A-V-F-S-G-A-S-L-W-I-A-L-V-F-L-V-G-V-L-N-S-F-I-S


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-T-P-N-P-N-K-Q-S-V-E-L-N-R-T-S-L-F-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-S-N-V-G-T-T-G-R-I-P-L-W-I-I-G-T-L-A-G-T-L-V-I-G-L-L-A-I-F-F-Y-G-S-Y-V-G-L-G-S-S-L


### FUNCTION Seems to be required for the assembly of the photosystem I complex ### SEQUENCE -M-N-I-K-S-E-F-F-R-V-D-F-I-I-G-A-R-R-L-S-N-Y-F-W-A-T-V-V-F-L-G-S-L-G-F-F-I-V-G-V-S-S-Y-L-Q-K-N-I-V-F-F-L-S-A-S-D-I-L-F-T-P-Q-G-I-V-M-C-F-Y-G-I-A-G-L-F-L-S-F-Y-L-W-F-T-I-F-L-D-I-G-S-G-Y-N-E-F-D-K-K-K-G-I-I-S-I-F-R-W-G-Y-P-G-Q-N-R-R-I-K-L-S-F-P-I-K-D-V-Q-A-I-K-L-E-V-K-E-V-L-P-A-R-R-M-I-Y-I-K-I-K-G-Q-Q-D-I-P-L-N-R-I-A-E-N-I-T-L-R-E-M-E-D-K-A-A-D-L-A-R-F-L-K-V-S-I-E-G-L


### FUNCTION May help in the organization of the PsaL subunit ### SEQUENCE -M-A-A-S-F-L-P-S-I-L-V-P-L-V-G-L-V-F-P-A-I-A-I-A-S-L-F-I-Y-I-E-Q-D-E-I-I


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-L-N-I-R-V-M-A-P-N-R-I-V-W-N-S-E-A-Q-E-I-I-L-S-T-N-S-G-Q-I-G-I-L-P-N-H-A-P-L-L-T-A-L-D-I-G-I-M-R-I-L-V-N-G-Q-W-T-S-M-A-L-M-G-G-F-A-L-V-D-N-N-Q-L-T-I-L-V-N-E-A-E-K-A-S-E-I-D-P-K-E-A-E-N-N-F-E-L-A-K-Q-N-L-A-A-A-E-G-R-K-Q-I-I-E-A-N-L-S-F-Q-R-A-K-A-R-L-D-A-V-N-A-S-S-R-L-G


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles ### SEQUENCE -M-A-K-K-S-I-I-H-R-D-K-K-R-E-N-L-V-K-K-Y-Q-E-I-R-N-S-I-K-E-N-I-K-Q-A-K-S-L-N-E-K-W-E-L-Q-K-Q-L-Q-A-L-P-R-N-S-S-P-T-R-I-H-R-R-C-F-V-T-G-R-P-R-A-V-Y-R-D-F-G-L-S-R-H-V-I-R-E-M-A-H-S-C-L-L-P-G-V-T-K-S-S-W


### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex ### SEQUENCE -M-I-S-I-L-T-Y-F-G-I-L-F-G-I-L-T-I-T-V-I-I-F-V-A-L-N-K-I-Q-L-I


### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions PetG is required for either the stability or assembly of the cytochrome b6-f complex ### SEQUENCE -M-V-E-P-L-L-S-G-I-V-L-G-L-I-P-I-T-L-A-G-L-F-V-T-A-Y-L-Q-Y-R-R-G-D-Q-L-D-F


### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-Q-Y-F-K-T-Y-L-S-T-A-P-V-I-A-T-I-W-F-G-F-L-A-G-L-L-I-E-I-N-R-F-F-P-D-A-L-V-L-P-Y-L


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-T-R-V-K-R-G-Y-V-A-R-R-R-R-K-K-I-L-H-L-T-S-G-F-Y-G-A-H-S-R-L-F-R-V-A-N-Q-K-A-I-R-A-L-A-Y-S-H-I-D-R-A-K-R-K-R-N-M-R-S-L-W-I-C-R-I-N-A-V-A-R-E-Q-N-I-S-Y-S-Y-L-I-K-S-L-K-E-K-K-I-L-L-N-R-K-M-L-A-Q-L-A-V-L-D-K-P-S-F-I-K-L-I-N-T-H-L-N


### FUNCTION Seems to play a role in the dimerization of PSII ### SEQUENCE -M-E-A-L-V-Y-T-F-L-L-V-G-T-L-G-I-I-F-F-A-I-F-F-R-E-P-P-R-V-P-V-K-D-K-K


### FUNCTION May play a role in photosystem I and II biogenesis ### SEQUENCE -M-E-T-G-I-L-V-V-I-F-I-S-C-L-L-V-S-F-T-G-Y-T-I-Y-T-A-F-G-Q-P-S-K-Q-L-R-D-P-F-E-E-H-E-D


### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-G-V-T-K-K-P-D-L-S-D-P-V-L-R-A-K-L-A-K-G-M-G-H-N-Y-Y-G-E-P-A-W-P-N-D-L-L-Y-I-F-P-V-C-I-F-G-T-I-A-C-T-V-G-L-S-V-L-E-P-V-I-V-G-E-P-A-N-P-F-A-T-P-L-E-I-L-P-E-W-Y-F-F-P-V-F-Q-I-L-R-T-V-P-N-K-L-L-G-V-L-L-M-A-G-V-P-V-G-L-L-T-V-P-F-I-E-N-V-N-K-F-Q-N-P-F-R-R-P-V-A-T-T-V-F-L-L-G-T-V-V-A-I-W-L-G-I-G-A-A-L-P-I-D-T-S-L-T-L-G-L-F


### FUNCTION A core subunit of photosystem II ### SEQUENCE -M-N-L-E-I-L-A-Q-L-T-A-L-A-F-I-V-V-S-G-P-L-V-I-A-L-L-A-F-R-K-G-N-L


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-T-L-K-I-F-V-Y-T-V-V-I-F-F-V-S-L-F-I-F-G-F-L-S-N-D-P-A-R-N-P-G-R-K-E-N


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation ### SEQUENCE -M-L-N-M-I-S-T-F-F-D-S-S-S-N-F-S-E-A-F-L-A-K-L-P-E-A-Y-A-I-F-D-P-I-V-D-V-M-P-I-I-P-V-F-F-L-L-L-A-F-V-W-Q-A-A-V-S-F-R


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-Y-I-Y-M-N-I-E-K-I-F-S-I-A-L-K-T-W-P-I-G-N-S-F-A-I-N-T-N-I-L-E-T-N-L-I-N-L-G-V-V-L-A-I-L-V-Y-F-G-K-G-I-L-S-N-L-L-E-N-R-K-Q-N-I-L-S-T-I-R-D-A-E-Q-C-Y-Q-E-A-A-A-K-L-K-Q-A-K-L-R-L-E-Q-A-K-L-K-A-D-E-I-R-I-Q-G-L-A-Q-L-E-R-E-K-L-E-L-I-K-A-A-D-E-D-S-K-R-L-E-E-S-K-N-V-T-I-R-F-E-Q-Q-R-A-I-E-Q-V-R-Q-Q-V-S-R-L-A-L-E-R-A-L-E-T-L-N-N-S-L-N-P-D-L-Q-A-R-I-I-D-N-H-I-G-L-L-R-T-I-E-G-V-T-E-S


### FUNCTION Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II , cyclic electron flow around PSI, and state transitions ### SEQUENCE -M-D-L-I-T-I-T-W-A-S-V-M-V-A-F-T-F-S-L-S-L-V-V-W-G-R-S-G-L


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface ### SEQUENCE -M-E-V-N-I-L-A-V-I-A-T-A-L-F-V-L-I-P-T-A-F-L-L-I-L-Y-V-K-T-E-S-A-G-S


### FUNCTION With S4 and S5 plays an important role in translational accuracy Located at the interface of the 30S and 50S subunits ### SEQUENCE -M-P-T-I-Q-Q-L-I-R-N-R-R-E-P-I-E-N-R-T-K-S-P-A-L-R-S-C-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-F-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-T-L-D-S-V-G-V-K-D-R-H-Q-G-R-S-K-Y-G-A-K-K-P-K


### FUNCTION One of the components of the core complex of photosystem II  and a proton gradient subsequently used for ATP formation It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization ### SEQUENCE -M-T-Q-Q-S-N-P-N-E-Q-T-V-E-L-N-R-T-I-L-Y-W-G-L-L-L-I-F-V-L-A-V-L-F-S-N-Y-F-F-N


### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-C-R-P-R-R-R-C-R-R-R-R-R-R-S-C-R-A-R-R-R-A-T-R-C-C-R-R-R-Y-R-L-S-R-R-Y


### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-R-C-R-S-Q-S-R-S-R-C-C-R-P-R-R-R-C-R-R-R-R-R-Q-S-C-R-A-R-R-R-A-T-R-C-C-R-R-R-Y-R-L-R-C-R-R-Y


### FUNCTION Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis They compact sperm DNA into a highly condensed, stable and inactive complex ### SEQUENCE -M-A-R-Y-R-C-C-R-S-Q-S-R-S-R-C-C-R-R-R-R-R-C-R-R-R-R-R-Q-R-C-R-A-R-R-T-A-M-R-C-C-R-R-R-Y-R-R-R-C-R-R-Y


### FUNCTION Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer  Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5 This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells ### SEQUENCE -M-Y-R-M-Q-L-L-S-C-I-A-L-S-L-A-L-I-T-N-S-A-P-T-S-S-S-T-K-K-T-Q-L-Q-L-E-H-L-L-L-D-L-Q-M-L-L-N-G-I-N-N-Y-K-N-P-K-L-T-R-M-L-T-F-K-F-Y-L-P-K-K-A-T-E-L-K-H-L-Q-C-L-E-E-E-L-K-P-L-E-E-V-L-N-L-A-Q-S-K-N-F-H-L-R-D-T-R-D-I-I-S-N-I-N-V-L-V-L-E-L-K-G-S-E-T-T-F-T-C-E-Y-D-D-D-T-A-T-I-I-E-F-L-N-G-W-I-T-F-C-Q-S-I-I-S-T-L-T


### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-F-I-Y-R-L-V-F-I-A-P-L-I-L-L-L-F-S-L-A-K-A-R-H-P-F-D-I-F-H-W-N-W-Q-D-F-Q-E-C-L-Q-V-N-N-I-T-I-G-E-Y-E-K-Y-A-R-H-E-T-L-D-Y-L-L-N-E-K-V-D-L-R-Y-K-C-N-I-K-C-Q-L-E-R-D-S-T-K-W-L-N-A-Q-G-R-M-D-L-D-L-M-N-T-T-D-K-A-S-K-S-I-T-K-C-M-E-K-A-P-E-E-L-C-A-Y-S-F-R-L-V-M-C-A-F-K-A-G-H-P-V-I-D-S-E


### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-F-N-T-R-L-A-I-F-L-L-L-I-V-V-S-L-S-Q-A-K-E-S-Q-P-F-D-F-F-E-G-T-Y-D-D-F-I-D-C-L-R-I-N-N-I-T-I-E-E-Y-E-K-F-D-D-T-D-N-L-D-N-V-L-K-E-N-V-E-L-K-H-K-C-N-I-K-C-Q-L-E-R-E-P-T-K-W-L-N-A-R-G-E-V-D-L-K-S-M-K-A-T-S-E-T-A-V-S-I-S-K-C-M-E-K-A-P-Q-E-T-C-A-Y-V-Y-K-L-V-I-C-A-F-K-S-G-H-S-V-I-K-F-D-S-Y-E-Q-I-Q-E-E-T-A-G-L-I-A-E-Q-Q-A-D-L-F-D-Y-D-T-I-D-L


### FUNCTION May be involved in cytochrome c oxidase biogenesis ### SEQUENCE -M-L-P-D-L-S-P-H-L-H-T-K-E-C-N-M-L-I-E-F-L-Q-R-C-H-S-E-K-P-I-G-K-M-I-G-K-C-S-Y-W-D-E-A-V-W-Q-C-T-K-K-E-R-I-W-R-R-D-N-N-P-A-Y-K-R-R-I-V-E-L-R-S-L-P-E-K-Y-W-T-P-A-L-H-K-L-K-E-D-G-V-L-I-G-G-A-D-Q-S-Q-G-C-K-I


### FUNCTION Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors ### SEQUENCE -M-Q-N-R-P-K-S-V-L-T-P-A-R-L-G-T-S-G-V-V-R-N-T-L-E-D-P-W-V-R-F-Q-I-E-L-E-F-V-Q-S-L-G-N-P-D-Y-L-T-F-L-A-Q-Q-G-C-F-D-K-P-E-F-I-N-Y-L-S-Y-L-Q-Y-W-K-S-P-S-Y-S-R-F-I-T-Y-P-F-C-L-H-M-L-D-L-L-Q-S-P-D-F-R-R-E-V-A-H-E-S-V-T-R-F-I-D-D-Q-M-L-L-H-W-K-N-Y-L-R-K-R-A-E-M-V-N-K-H-V-Q-S-L-D-A-M-A-T-P-G-P-G-P-S-S


### FUNCTION Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions ### SEQUENCE -M-G-R-R-K-S-K-R-K-P-P-P-K-R-K-N-I-E-P-L-D-Q-Q-F-N-C-P-F-C-N-H-E-K-S-C-E-V-K-M-D-K-S-R-N-T-A-K-I-T-C-R-V-C-L-E-D-F-Q-T-G-I-N-F-L-S-E-P-I-D-V-Y-N-D-W-V-D-A-C-E-T-A-N


### FUNCTION Involved in transport from the endoplasmic reticulum to the Golgi apparatus ### SEQUENCE -M-G-F-G-D-W-F-K-S-A-L-S-F-L-G-L-Y-K-K-K-A-T-I-V-F-V-G-L-D-N-A-G-K-S-T-L-L-A-M-L-K-N-S-A-T-T-T-V-A-P-T-Q-Q-P-T-S-Q-E-L-V-M-G-S-I-R-F-K-T-F-D-L-G-G-H-E-V-A-R-Q-L-W-E-Q-Y-V-T-N-S-D-G-I-V-F-L-V-D-S-A-D-P-S-R-F-E-E-S-R-R-T-L-Q-E-L-L-D-N-H-D-L-A-T-T-P-I-L-I-L-S-N-K-V-D-I-Q-T-A-V-S-M-E-T-M-V-Q-S-F-G-I-Q-H-L-L-T-G-K-G-G-S-N-L-R-S-D-Q-R-P-L-E-V-F-P-C-S-V-I-N-R-F-G-Y-T-D-G-F-K-W-L-S-K-Y-L


### FUNCTION Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria ### SEQUENCE -M-N-F-K-L-I-F-L-V-A-L-V-L-M-A-A-F-L-G-Q-T-E-G-R-R-F-K-K-F-L-K-K-V-E-G-A-G-R-R-V-A-N-A-A-Q-K-G-L-P-L-A-A-G-V-K-G-L-V-G


### FUNCTION Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria ### SEQUENCE -M-N-F-T-K-L-F-I-L-V-A-I-A-V-L-V-V-V-G-V-Q-P-V-D-G-A-P-R-W-K-F-G-K-R-L-E-K-L-G-R-N-V-F-R-A-A-K-K-A-L-P-V-I-A-G-Y-K-A-L-G


### FUNCTION Has antifungal activity against the entomopathogenic fungus Mnisopliae, but does not display any antifungal activity against Scerevisiae nor any antimicrobial activity against Mluteus, Bsubtilis, and Ecoli ### SEQUENCE -M-K-I-A-F-I-V-A-I-S-L-A-F-L-A-V-T-S-C-I-E-F-E-K-S-T-E-S-H-D-I-Q-K-R-G-V-T-I-T-V-K-P-P-F-P-G-C-V-F-Y-E-C-I-A-N-C-R-S-R-G-Y-K-N-G-G-Y-C-T-I-N-G-C-Q-C-L-R


### FUNCTION May be required for cytochrome c complex  assembly and function, COX being the terminal component of the mitochondrial respiratory chain ### SEQUENCE -M-S-S-I-S-S-S-S-S-N-V-R-M-D-R-R-F-D-W-V-G-P-P-D-N-L-S-K-I-R-K-I-M-L-R-R-V-D-N-E-S-E-L-E-R-Q-Y-R-L-A-R-E-E-L-N-Q-W-N-S-D-F-W-A-E-H-N-Q-L-F-D-R-Q-K-S-D-F-V-E-R-K-Q-Q-E-L-G-R-L-E-H-V-S-A-N-E-L-S-E-F-Y-R-D-F-L-N-D-R-H-V-A-M-M-A-Y-N-K-E-W-Y-R-R-N-L-Q-L-I-W-P-A-L-K-V-N-V-V-R-F-F-R-M-A-R-R


### FUNCTION Highly acidic peptide that may have antibacterial activity ### SEQUENCE -M-S-S-K-T-L-L-V-L-L-L-V-G-V-L-V-S-T-F-F-T-A-D-A-Y-P-A-S-M-D-N-Y-D-D-A-L-E-E-L-D-N-L-D-L-D-D-Y-F-D-L-E-P-A-D-F-V-L-L-D-M-W-A-N-M-L-E-S-S-D-F-D-D-M-E


### FUNCTION Microtubule inner protein  in cilia axoneme, which is required for motile cilia beating ### SEQUENCE -M-F-L-T-A-V-N-P-Q-P-L-S-T-P-S-W-Q-I-E-T-K-Y-S-T-K-V-L-T-G-N-W-M-E-E-R-R-K-F-T-R-D-T-D-K-T-P-Q-S-I-Y-R-K-E-Y-I-P-F-P-D-H-R-P-D-Q-I-S-R-W-Y-G-K-R-K-V-E-G-L-P-Y-K-H-L-I-T-H-H-Q-E-P-P-H-R-Y-L-I-S-T-Y-D-D-H-Y-N-R-H-G-Y-N-P-G-L-P-P-L-R-T-W-N-G-Q-K-L-L-W-L-P-E-K-S-D-F-P-L-L-A-P-P-T-N-Y-G-L-Y-E-Q-L-K-Q-R-Q-L-T-P-K-A-G-L-K-Q-S-T-Y-T-S-S-Y-P-R-P-P-L-C-A-M-S-W-R-E-H-A-V-P-V-P-P-H-R-L-H-P-L-P-H-F


### FUNCTION Substrate-recognition component of the SCF -type E3 ubiquitin ligase complex ### SEQUENCE -M-A-S-W-L-P-E-T-L-F-E-T-V-G-Q-G-P-P-P-S-K-D-Y-Y-Q-L-L-V-T-R-S-Q-V-I-F-R-W-W-K-I-S-L-R-S-E-Y-R-S-T-K-P-G-E-A-K-E-T-H-E-D-F-L-E-N-S-H-L-Q-G-Q-T-A-L-I-F-G-A-R-I-L-D-Y-V-I-N-L-C-K-G-K-F-D-F-L-E-R-L-S-D-D-L-L-L-T-I-I-S-Y-L-D-L-E-D-I-A-R-L-C-Q-T-S-H-R-F-A-K-L-C-M-S-D-K-L-W-E-Q-I-V-Q-S-T-C-D-T-I-T-P-D-V-R-A-L-A-E-D-T-G-W-R-Q-L-F-F-T-N-K-L-Q-L-Q-R-Q-L-R-K-R-K-Q-K-Y-G-N-L-R-E-K-Q-P


### FUNCTION Accessory component of the V0 complex of vacuolar ### SEQUENCE -M-K-P-L-V-S-P-G-L-A-K-A-C-T-G-L-S-L-I-G-I-V-F-L-L-V-L-S-Y-L-F-S-I-E-A-E-T-L-M-H-D-L-V-G-S-G-L-T-G-K-Q-V-A-K-T-C-L-G-A-V-V-I-Y-A-V-F-F-L-F-C-G-S-Q-V-I-V-S-R-Y-Q-K-P-V-R-I


### FUNCTION Facilitates protein transport into the nucleus Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import ### SEQUENCE -M-S-D-F-N-A-I-A-Q-Q-F-T-E-F-Y-Y-K-T-F-D-T-D-R-A-Q-L-A-P-L-Y-R-E-N-S-M-L-T-F-E-Q-S-P-F-L-G-T-A-N-I-V-G-K-L-Q-E-L-P-F-Q-R-I-E-H-Q-V-A-T-V-D-A-Q-P-S-N-E-S-G-G-I-L-V-V-V-S-G-A-L-L-V-E-E-E-R-R-P-M-S-Y-T-Q-T-F-Q-L-L-P-A-D-G-A-Y-Y-V-F-N-D-V-F-R-L-V-Y-P-A-A


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-V-N-L-P-A-Q-K-H-V-W-V-G-L-Q-S-I-Y-G-I-G-R-T-R-S-K-K-L-C-E-S-A-G-V-T-S-T-T-K-I-R-D-L-S-E-P-E-I-E-R-L-R-A-E-V-G-K-Y-V-V-E-G-D-L-R-R-E-I-G-I-A-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-G-L-P-L-R-G-Q-R-T-R-T-N-A-R-T-R-K-G-P-R-K-A-I-R-K


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-T-M-E-A-K-A-I-L-R-T-A-R-I-S-P-Q-K-A-R-L-V-A-D-Q-V-R-G-L-S-A-E-R-A-V-N-L-L-K-F-S-D-K-K-A-A-H-L-I-K-K-V-V-E-S-A-I-A-N-A-E-N-N-Q-G-A-D-V-D-E-L-K-V-K-T-I-M-V-D-E-G-P-S-L-K-R-F-M-A-R-A-K-G-R-G-T-R-I-L-K-R-T-S-H-I-T-V-V-V-G-A-A-K


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-M-Q-S-Y-L-D-V-A-D-N-S-G-A-K-E-V-M-C-I-K-V-L-G-G-S-K-R-R-Y-A-H-I-G-D-I-I-K-V-T-V-K-D-A-I-P-R-G-K-V-K-K-G-E-V-Y-D-A-V-V-V-R-T-R-K-G-V-R-R-P-D-G-S-L-I-R-F-D-G-N-A-A-V-L-L-N-N-K-Q-E-P-I-G-T-R-I-F-G-P-V-T-R-E-L-R-S-E-K-F-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-S-M-I-H-R-D-I-K-R-A-K-L-A-K-K-F-A-G-K-R-D-A-L-K-K-I-L-S-S-Q-D-A-S-Y-E-E-K-I-D-A-S-T-K-L-Q-K-L-P-R-D-S-S-P-S-R-H-R-N-R-C-E-L-S-G-R-P-R-G-V-Y-R-K-F-G-L-G-R-N-M-L-R-K-A-T-M-N-G-D-V-P-G-L-R-K-A-S-W


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-T-T-F-T-A-K-S-E-T-V-Q-R-D-W-Y-L-V-D-A-A-G-K-T-L-G-R-L-S-T-E-L-A-R-R-L-R-G-K-H-K-P-V-Y-T-P-H-V-D-T-G-D-Y-L-V-V-I-N-A-E-K-I-V-V-T-G-N-K-L-K-D-K-K-Y-H-R-F-T-G-Y-I-G-N-L-K-T-E-S-L-E-Q-A-L-Q-R-H-P-E-R-V-I-E-I-A-V-K-G-M-L-P-K-G-P-L-G-R-T-M-Y-R-K-L-K-V-Y-S-G-A-E-H-P-H-A-A-Q-Q-P-Q-V-L-D-I


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-L-P-A-Q-H-K-L-N-S-S-M-Q-F-R-T-V-M-R-K-G-R-R-A-G-S-K-T-V-V-V-H-L-W-D-S-A-E-S-L-D-G-T-E-K-Q-G-E-V-A-S-F-G-G-P-R-F-G-L-V-V-S-K-A-V-G-N-A-V-V-R-H-R-T-S-R-R-L-R-H-I-C-A-S-I-A-E-K-S-P-E-L-L-S-P-T-H-H-V-V-I-R-A-L-A-G-A-G-N-A-T-S-A-E-L-E-R-D-I-R-Y-G-L-G-K-A-S-R-V-R-T-N-K


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-Q-Y-E-L-M-I-I-L-D-P-S-Q-D-E-R-T-V-A-P-S-L-D-K-F-L-E-V-V-R-K-D-K-G-D-V-V-K-V-D-V-W-G-K-R-R-L-A-Y-P-I-D-K-K-E-E-G-V-Y-A-V-V-D-L-K-C-E-S-A-T-V-L-E-L-D-R-V-L-N-L-N-D-G-V-L-R-T-K-V-L-R-L-D-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-I-L-T-A-A-V-E-N-L-G-V-A-G-D-I-V-E-V-K-N-G-Y-G-R-N-L-L-L-P-R-G-L-A-I-V-A-T-P-G-A-E-K-Q-I-E-G-I-K-R-A-Q-E-A-R-E-I-R-D-L-D-H-A-R-E-V-K-V-A-L-E-A-L-E-G-V-T-I-A-V-R-T-S-E-S-G-K-L-F-G-S-V-K-T-D-D-I-V-D-A-V-K-A-A-G-G-P-N-L-D-K-R-A-I-V-L-P-K-N-L-V-K-T-T-G-K-Y-Q-V-E-A-K-L-T-D-G-I-V-S-R-V-K-F-E-V-V-A-A


### FUNCTION Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ### SEQUENCE -M-S-S-N-S-I-N-A-E-A-R-A-E-L-A-E-L-I-K-E-L-A-V-V-H-G-E-V-T-L-S-S-G-K-K-A-D-Y-Y-I-D-V-R-R-A-T-L-H-A-R-A-S-R-L-I-G-Q-L-L-R-E-A-T-A-D-W-D-Y-D-A-V-G-G-L-T-L-G-A-D-P-V-A-T-A-I-M-H-A-D-G-R-D-I-N-A-F-V-V-R-K-E-A-K-K-H-G-M-Q-R-R-I-E-G-P-D-L-T-G-K-K-V-L-V-V-E-D-T-T-T-T-G-N-S-P-L-T-A-V-A-A-L-R-E-A-G-I-E-V-V-G-V-A-T-V-V-D-R-A-T-G-A-D-E-V-I-A-A-E-G-L-P-Y-R-S-L-L-G-L-S-D-L-G-L-N


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-T-V-R-P-I-V-I-H-G-D-P-V-L-H-N-P-T-Q-L-V-T-E-D-V-S-E-L-Q-E-L-I-A-D-M-Y-E-T-M-D-V-A-N-G-V-G-L-A-A-N-Q-I-G-V-S-K-R-I-F-V-Y-D-C-P-D-D-E-G-V-M-H-K-G-C-F-I-N-P-V-L-E-T-S-E-I-P-E-T-M-P-A-D-D-G-S-D-E-E-G-C-L-S-V-P-G-E-G-F-P-T-G-R-A-H-W-A-K-V-T-G-L-N-E-K-G-E-E-V-S-V-E-A-E-G-F-L-A-R-C-F-Q-H-E-V-G-H-L-D-G-F-L-Y-T-D-V-L-I-G-R-W-K-R-M-A-K-K-A-I-K-A-N-G-W-T-E-P-G-L-T-W-M-P-G-E-D-E-D-P-F-G-H-D-A


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-F-L-Y-A-A-L-G-G-F-F-G-G-F-L-R-W-S-L-A-Q-L-F-P-G-K-R-A-T-L-A-A-N-T-L-A-C-L-A-G-G-F-F-V-S-L-D-L-P-H-L-Y-T-V-L-L-I-A-G-F-C-G-A-L-S-T-W-S-T-L-A-K-E-L-G-Q-L-L-N-E-K-K-W-W-P-M-L-G-Y-L-S-L-T-F-T-L-G-Y-S-A-V-F-L-G-M-R-L


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-Q-K-L-I-Q-G-L-G-V-G-A-G-A-A-L-G-V-C-V-R-L-A-L-T-L-W-L-G-D-S-A-W-P-I-L-T-I-N-V-L-G-A-F-L-M-G-W-L-R-P-N-A-F-W-G-T-G-F-L-G-G-F-T-T-F-S-A-M-M-L-N-D-V-S-F-Y-F-F-T-A-V-G-C-I-L-A-W-L-A-G-D-R-L-A-R


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-S-S-P-S-A-P-L-A-T-P-D-V-E-L-D-V-H-T-L-S-S-E-N-L-P-W-L-C-I-V-W-D-D-P-V-N-L-M-S-Y-V-T-Y-V-F-Q-T-V-L-G-F-S-K-K-R-A-T-E-L-M-M-Q-V-H-T-E-G-K-A-V-V-S-S-G-E-K-D-K-V-E-G-D-V-K-K-L-H-T-A-G-L-W-A-T-M-Q-Q-A-G


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-S-I-G-T-D-L-V-H-I-S-A-F-A-E-Q-L-A-Q-P-G-S-S-F-M-E-V-F-S-A-G-E-R-R-K-A-N-E-R-Q-A-S-R-Y-A-E-H-L-A-G-R-W-A-A-K-E-S-F-I-K-A-W-S-Q-A-I-Y-G-Q-P-P-V-I-A-E-E-A-V-V-W-R-D-I-E-V-R-A-D-A-W-G-R-V-A-I-E-L-A-P-E-L-A-A-V-V-R-E-S-I-G-E-F-S-S-S-L-S-I-S-H-D-G-D-Y-A-V-A-T-C-V-L-T-I-Q


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-I-V-K-T-G-G-K-Q-Y-K-V-A-E-G-D-L-V-K-V-E-K-I-E-G-E-P-G-A-S-V-A-L-T-P-V-L-L-V-D-G-A-D-V-T-T-A-A-D-K-L-A-S-V-S-V-N-T-E-I-V-E-H-T-K-G-P-K-I-K-I-L-K-Y-K-N-K-T-G-Y-K-K-R-Q-G-H-R-Q-P-L-T-V-L-K-V-T-G-I-K


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-Q-I-K-R-N-K-T-N-E-K-A-R-L-R-N-Q-A-V-R-S-A-V-R-T-E-I-R-K-F-N-A-A-I-E-A-G-D-K-D-A-A-Q-A-Q-L-R-T-A-S-R-A-L-D-K-A-V-T-K-G-V-F-H-I-N-N-A-A-N-K-K-S-N-M-A-T-A-F-N-K-L-G


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-I-E-V-F-N-E-S-G-Y-D-G-V-N-E-E-M-L-I-D-V-L-S-F-A-L-G-E-M-D-I-H-P-D-A-E-A-S-I-H-I-V-D-V-D-T-I-A-D-L-H-V-K-W-L-D-L-E-G-P-T-D-V-M-S-F-P-M-D-E-L-T-P-G-Y-S-R-P-D-G-A-T-P-G-P-A-M-L-G-D-I-V-L-C-P-E-F-A-A-K-Q-A-T-K-A-G-H-D-L-A-H-E-L-A-L-L-T-V-H-G-S-L-H-L-L-G-Y-D-H-V-D-P-A-E-E-R-E-M-F-A-L-Q-N-E-L-L-A-D-W-Y-D-N-V-E-A-R-G-V-T-Y-Q-P-K-P-S-G-A-G-A-F-P-T-A-A-D-R-L-E-L-D-E-K-M-E-A-D-D-S-G-F-G-G-V-E-S


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-T-E-Q-E-L-Q-I-G-K-V-V-K-S-H-G-I-R-G-E-V-V-V-E-L-S-T-D-D-P-D-I-R-F-A-I-G-E-V-L-N-G-K-Q-A-G-K-E-H-S-L-T-I-D-A-A-R-M-H-Q-G-R-L-L-V-K-F-A-E-V-P-D-R-T-A-A-D-S-L-R-G-T-R-F-F-A-A-P-L-E-D-E-D-D-E-D-G-F-Y-D-H-E-L-E-G-L-R-V-I-H-E-G-E-D-I-G-E-V-T-G-V-M-H-G-P-A-G-E-I-L-E-V-R-L-T-S-G-K-E-T-L-I-P-F-V-H-A-I-V-P-E-V-D-L-E-E-G-T-A-T-I-T-P-P-E-G-L-L-D-L


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-I-L-D-K-I-D-A-A-S-L-R-D-D-V-P-A-F-R-A-G-D-T-L-D-V-H-V-K-V-I-E-G-T-T-T-R-T-Q-L-F-K-G-V-V-I-R-R-Q-G-G-G-I-R-E-T-F-T-V-R-K-V-S-F-G-I-G-V-E-R-T-F-P-V-H-S-P-N-I-E-K-I-E-V-I-R-R-G-D-V-R-R-A-K-L-Y-Y-L-R-E-L-R-G-K-A-A-R-I-K-E-K-R


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-D-E-I-L-F-E-A-E-E-R-M-T-A-T-V-E-H-T-R-E-D-L-T-T-I-R-T-G-R-A-N-P-A-M-F-N-G-V-M-A-E-Y-Y-G-V-P-T-P-I-T-Q-M-S-G-I-T-V-P-E-P-R-M-L-L-I-K-P-Y-E-M-S-S-M-Q-V-I-E-N-A-I-R-N-S-D-L-G-V-N-P-T-N-D-G-Q-V-L-R-V-T-I-P-Q-L-T-E-E-R-R-K-D-M-V-K-L-A-K-G-K-G-E-D-G-K-I-A-I-R-N-I-R-R-K-G-M-D-Q-L-K-K-L-Q-K-D-G-D-A-G-E-D-E-V-Q-A-A-E-K-E-L-D-K-V-T-A-G-F-V-A-Q-V-D-E-V-V-A-R-K-E-K-E-L-M-E-V


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-F-P-T-T-E-I-L-S-A-L-I-E-P-L-A-A-S-H-K-F-D-L-E-G-L-K-V-T-K-A-G-P-K-S-A-V-A-I-K-V-D-S-D-S-R-P-D-L-D-Q-L-E-V-F-S-Q-E-I-G-E-L-F-D-A-A-E-Q-R-G-E-L-N-F-G-A-G-Y-T-L-E-V-S-T-P-G-V-D-N-P-L-T-L-P-R-H-W-R-R-N-R-G-R-L-V-A-L-D-Q-D-G-K-K-R-V-A-R-I-G-A-L-N-D-A-E-T-H-V-V-L-I-E-R-N-K-K-L-L-E-V-T-T-L-E-L-A-H-S-P-R-A-V-V-E-I-E-F-A-K-P-A-Q-D-E-T-A-L-A-E-S-T-F-D-E-A-T-A


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-D-N-A-R-A-A-R-M-A-K-R-I-Q-T-I-V-A-S-A-I-E-R-D-I-K-D-R-R-L-E-F-V-T-I-T-D-V-T-M-T-G-D-L-H-D-A-K-V-F-Y-T-V-R-G-A-S-I-E-E-E-P-D-L-E-A-A-A-E-A-L-H-R-A-R-G-Q-L-R-K-I-V-G-Q-Q-L-G-V-R-F-T-P-T-L-T-Y-S-I-D-T-V-P-E-A-S-A-H-M-E-A-L-L-D-R-A-R-K-R-D-E-E-L-A-K-L-R-E-G-A-A-P-A-G-D-A-D-P-Y-K-T-S-S-K-S-E-S-E-E


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-L-T-S-E-Q-K-K-S-I-L-S-E-F-G-L-H-E-T-D-T-G-S-P-E-A-Q-I-A-L-L-T-N-R-I-N-N-L-T-E-H-L-K-F-H-K-H-D-H-H-S-R-R-G-L-L-L-L-V-G-R-R-R-G-L-L-K-Y-L-A-D-N-N-V-D-R-Y-R-D-L-I-A-R-L-G-L-R-R


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-Y-C-P-F-C-Q-H-D-H-S-K-V-I-D-S-R-V-I-D-A-G-S-A-I-R-R-R-R-E-C-S-K-C-E-G-R-F-T-T-I-E-K-A-V-L-L-V-V-K-R-N-G-V-T-E-P-F-S-R-E-K-V-V-T-G-V-R-R-A-C-Q-G-R-D-V-S-D-D-A-L-K-R-L-A-Q-Q-V-E-E-T-V-R-S-N-G-S-S-Q-V-R-A-N-D-I-G-L-A-I-L-D-P-L-R-E-L-D-E-V-A-Y-L-R-F-A-S-V-Y-K-S-F-D-S-A-D-D-F-E-K-E-I-R-L-M-R-R-R-G-R-D


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-T-D-L-A-A-I-K-I-V-R-L-D-K-E-L-P-L-P-K-R-A-H-R-G-D-A-G-V-D-L-H-A-T-T-D-A-V-I-A-P-G-H-R-E-I-V-G-T-G-I-A-I-A-L-P-L-G-T-V-G-L-V-H-P-R-S-G-L-A-A-R-E-G-L-S-I-V-N-A-P-G-T-I-D-A-D-Y-R-G-E-I-K-V-C-L-I-N-L-D-P-E-K-P-I-M-I-T-R-G-D-R-I-A-Q-L-V-I-Q-K-V-E-L-V-D-F-E-E-V-E-E-L-D-D-T-V-R-G-D-Q-G-Y-G-S-T-G-K-T-A


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-K-V-S-A-D-T-P-G-H-D-D-P-G-P-G-R-R-L-G-L-D-V-G-T-V-R-I-G-V-A-A-S-D-R-D-A-K-L-A-M-P-V-E-T-V-P-R-E-T-G-F-K-G-P-D-L-A-D-I-D-R-L-V-A-I-V-E-E-Y-N-A-V-E-V-I-V-G-L-P-T-D-L-Q-G-N-G-S-A-S-V-K-H-A-K-E-I-A-F-R-V-R-R-R-L-T-N-A-G-K-N-I-P-V-R-L-G-D-E-R-L-T-T-V-V-A-T-Q-A-L-R-A-S-G-V-S-E-K-A-G-R-K-V-I-D-Q-A-A-A-V-E-I-L-Q-T-W-L-D-A-R-T-R-A-L-E-P-Q-S-T-D-T-Q-D-F-D-E-K-G-N-F-P-G


### FUNCTION Removes the formyl group from the N-terminal Met of newly synthesized proteins Requires at least a dipeptide for an efficient rate of reaction N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions ### SEQUENCE -M-A-V-R-E-V-R-L-F-G-D-P-V-L-V-S-R-A-D-E-V-V-D-F-D-E-S-L-S-T-L-I-D-D-M-F-D-T-M-E-D-A-G-G-V-G-L-A-A-N-Q-V-G-V-L-R-R-V-F-V-F-D-T-S-H-Q-E-G-G-L-R-G-H-V-I-N-P-V-W-E-P-L-T-E-D-T-Q-T-G-K-E-G-C-L-S-I-P-D-V-S-A-E-T-T-R-Y-E-T-V-R-L-S-G-Q-D-R-D-G-N-P-V-G-F-V-A-N-G-L-L-A-R-C-I-Q-H-E-T-D-H-L-D-G-V-L-F-L-K-R-L-D-P-A-E-R-K-A-A-M-G-V-I-R-A-S-A-W-F-N-K


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-A-K-E-G-L-P-A-V-E-L-P-D-A-S-G-L-K-V-A-V-V-T-A-R-W-N-A-E-I-C-D-R-L-H-K-H-A-V-D-A-G-R-A-A-G-A-T-V-S-E-Y-R-V-I-G-A-L-E-L-P-V-V-V-Q-E-L-A-R-T-H-D-A-V-V-A-L-G-C-V-V-R-G-G-T-P-H-F-D-Y-V-C-D-S-V-T-E-G-L-T-R-I-A-L-D-T-S-T-P-I-G-N-G-V-L-T-T-N-T-E-E-Q-A-V-E-R-S-G-G-E-G-S-V-E-D-K-G-A-E-A-M-V-A-A-L-D-T-A-L-V-L-S-Q-I-R-A-T-E-G


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-S-L-G-P-W-E-I-G-I-I-V-L-L-I-I-V-L-F-G-A-K-K-L-P-D-A-A-R-S-I-G-R-S-M-R-I-F-K-S-E-V-K-E-M-N-K-D-G-D-T-P-E-Q-Q-Q-Q-P-Q-Q-Q-I-A-P-N-Q-I-E-A-P-Q-P-N-F-E-Q-H-Y-Q-G-Q-Q-V-Q-Q-P-Q-N-P-Q-T-P-D-Y-R-Q-N-Y-E-D-P-N-R-T-S


### FUNCTION Probably functions as a manganese efflux pump ### SEQUENCE -M-P-F-L-Q-I-S-L-L-S-I-G-V-A-A-D-A-F-A-C-S-V-V-R-G-T-A-I-Q-V-N-L-F-K-R-A-L-V-L-A-G-I-F-G-V-F-Q-A-A-M-P-L-I-G-W-F-I-G-R-F-F-A-G-I-T-F-I-A-E-I-D-H-W-I-A-F-A-L-L-G-I-V-G-T-K-M-I-W-D-A-F-Q-P-E-D-D-E-T-I-V-D-D-G-R-V-Q-F-R-P-A-I-I-L-G-L-A-T-S-I-D-A-L-A-V-G-M-G-L-A-F-V-E-V-S-I-L-K-V-A-L-S-M-G-S-I-T-F-A-L-S-L-A-G-A-W-I-G-H-H-G-G-G-K-F-G-K-W-A-T-I-L-G-G-I-I-L-I-G-I-G-A-N-I-V-Y-E-H-L-S-A


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-S-V-N-A-K-K-K-R-R-E-I-L-K-S-A-K-G-Y-R-G-Q-R-S-R-L-Y-R-K-A-K-E-Q-W-L-H-S-M-T-Y-S-Y-R-D-R-R-A-R-K-S-E-F-R-K-L-W-I-Q-R-I-N-A-A-A-R-M-N-G-I-T-Y-N-R-L-I-Q-G-L-R-L-A-E-I-E-V-D-R-K-I-L-A-D-L-A-V-N-D-F-A-T-F-S-A-I-C-E-A-A-K-A-A-L-P-E-D-V-N-A-P-K-A-A


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-V-R-Y-V-K-F-S-R-T-A-N-R-G-V-H-I-S-A-E-A-R-I-N-E-R-I-R-V-P-E-V-R-L-V-G-P-N-G-E-Q-V-G-I-V-R-I-E-D-A-R-K-L-A-F-D-A-D-L-D-L-V-E-V-A-P-N-A-K-P-P-V-C-K-I-M-D-Y-G-K-F-K-Y-E-A-A-Q-K-A-R-E-S-R-K-N-Q-Q-Q-T-V-V-K-E-Q-K-L-R-P-K-I-D-D-H-D-Y-E-T-K-K-N-N-V-I-R-F-L-E-K-G-S-K-V-K-V-T-I-M-F-R-G-R-E-Q-A-R-P-E-L-G-Y-R-L-L-E-R-L-A-N-D-V-V-D-F-G-I-V-E-T-R-A-K-Q-D-G-R-N-M-T-M-V-L-G-P-V-R-K-G-K-K


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-P-E-I-S-R-D-Q-V-A-H-L-A-K-L-S-R-L-A-L-T-E-E-E-L-E-Q-F-A-G-Q-I-D-D-I-V-G-Y-V-S-A-V-Q-N-V-D-A-A-G-V-E-P-M-S-H-P-H-S-I-A-T-T-M-R-E-D-V-V-H-K-T-L-D-A-A-A-A-L-D-Q-A-P-A-V-E-D-G-R-F-M-V-P-Q-I-L-G-E-G-D


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-S-S-V-G-W-G-E-I-F-L-L-V-V-V-G-L-V-V-I-G-P-E-R-L-P-R-L-I-Q-D-A-R-A-A-L-L-A-A-R-T-A-I-D-N-A-K-Q-S-L-D-S-D-F-G-S-E-F-D-E-I-R-K-P-L-T-Q-V-A-Q-Y-S-R-M-S-P-K-T-A-I-T-K-A-L-F-D-N-D-S-S-F-L-D-D-F-D-P-K-K-I-M-A-E-G-T-E-G-E-A-Q-R-N-K-Q-A-A-D-N-N-A-N-V-V-E-R-P-A-D-G-S-T-A-R-P-T-Q-N-D-P-K-D-G-P-N-Y-S-G-G-V-S-W-T-D-I-I


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-A-K-Y-Q-T-I-E-A-A-V-R-S-E-F-G-K-G-S-A-R-R-A-R-V-A-G-Q-I-P-A-V-V-Y-G-A-D-V-E-S-N-L-H-V-T-I-D-H-R-T-F-A-A-L-V-R-Q-E-G-V-N-A-V-L-E-L-D-I-E-G-Q-K-Q-L-T-M-I-K-H-I-D-Q-N-V-L-T-F-H-I-D-H-L-D-L-L-A-I-K-R-G-E-K-V-E-V-D-V-P-V-I-V-E-G-E-P-A-P-G-T-M-W-V-Q-D-A-D-T-I-K-V-E-A-D-V-L-S-I-P-E-E-F-T-V-S-I-E-G-L-E-L-G-A-Q-I-T-A-A-D-I-K-L-E-G-D-T-T-L-V-E-D-P-E-T-L-I-V-N-I-V-L-P-A-V-E-E-E-D-T-E-E-D-E-A-A-E-E-A-A-T-E


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-N-N-S-P-L-L-V-V-G-L-G-N-P-G-P-K-Y-V-G-T-R-H-N-I-G-F-E-V-A-E-E-L-V-S-R-S-F-G-S-F-S-V-H-K-R-S-N-T-D-I-A-Q-L-P-G-L-I-V-A-K-P-R-S-F-M-N-L-S-G-T-P-I-R-A-L-C-D-F-F-K-I-S-P-A-N-V-I-V-V-H-D-E-L-E-L-D-F-G-S-V-K-L-R-Q-G-G-G-D-H-G-H-N-G-L-K-S-T-S-K-S-L-G-T-K-D-Y-W-K-L-S-M-G-I-G-R-P-P-G-R-M-D-P-A-S-F-V-L-K-P-F-G-K-Q-E-L-A-D-I-P-I-M-A-A-D-A-A-D-L-V-E-K-H-L-Q-Q-G


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-N-E-K-R-K-E-I-V-A-R-Y-A-E-R-R-A-E-L-K-A-I-I-S-N-P-N-T-S-D-E-D-R-L-D-A-Q-F-E-L-N-S-Q-P-R-D-A-A-A-V-R-V-R-N-R-D-S-H-D-G-R-P-R-G-Y-L-R-K-F-G-L-S-R-V-R-M-R-E-M-A-H-R-G-E-L-P-G-V-R-K-S-S-W


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-A-K-K-K-K-K-V-D-E-N-N-S-V-L-A-T-N-R-K-A-R-H-D-Y-H-I-I-D-T-W-E-A-G-V-V-L-L-G-T-E-I-K-S-L-R-E-G-K-V-S-L-V-D-S-F-A-T-I-D-N-G-E-I-W-L-Q-H-L-H-I-P-Q-Y-S-M-G-S-W-T-N-H-T-P-K-R-T-R-K-L-L-L-H-R-N-E-I-D-S-L-M-G-K-V-R-D-G-N-R-T-L-V-P-L-K-L-Y-L-K-N-G-R-V-K-L-E-L-G-L-A-Q-G-K-Q-D-Y-D-K-R-Q-D-I-K-R-R-T-E-E-R-E-V-T-R-E-L-G-R-R-I-K-G-I-N-A


### FUNCTION Nucleoside triphosphate pyrophosphatase May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-Q-I-V-L-A-S-Q-S-P-S-R-R-R-I-L-N-S-A-G-V-E-P-L-I-H-P-A-D-V-D-E-D-A-L-L-H-S-L-N-G-S-A-P-E-E-I-V-R-Q-L-A-L-A-K-A-Q-V-V-A-P-S-Y-P-G-D-V-V-I-G-G-D-S-M-L-L-I-D-A-T-L-Q-G-K-P-H-T-R-E-A-T-I-E-R-W-K-Q-Q-R-G-N-K-A-T-L-I-T-G-H-A-I-I-F-G-D-E-V-I-V-E-S-S-S-T-N-I-H-F-A-E-A-S-D-V-D-I-E-R-Y-A-D-S-G-E-P-L-E-C-A-G-A-F-T-L-E-A-L-G-G-W-F-I-D-S-I-E-G-D-P-S-S-V-I-G-L-S-L-P-V-V-R-R-A-L-Y-R-L-G-F-N-A-S-D-F-W-N-M


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-N-V-N-I-K-P-L-E-D-K-I-L-V-Q-I-N-E-A-E-T-T-T-A-S-G-L-V-I-P-D-S-A-K-E-K-P-Q-E-A-T-V-I-A-V-G-P-G-R-F-D-D-K-G-N-R-I-P-L-D-I-K-E-D-D-V-V-I-F-S-R-Y-G-G-T-E-I-K-F-G-G-V-E-Y-L-L-L-S-A-R-D-I-L-A-I-V-E-K


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-S-T-Y-H-P-K-S-G-D-I-T-R-K-W-Y-V-I-D-A-T-D-V-V-L-G-R-L-A-T-H-A-A-D-L-L-R-G-K-G-K-P-L-Y-A-P-N-V-D-C-G-D-H-V-I-V-I-N-A-D-K-V-A-V-T-S-N-K-R-E-R-E-M-R-Y-R-H-S-G-Y-P-G-G-L-K-S-M-T-L-G-R-S-L-D-L-H-P-E-R-T-I-E-D-S-I-V-G-M-M-P-H-N-K-L-T-A-A-S-A-K-K-L-H-V-F-S-G-S-E-H-P-Y-A-A-Q-K-P-E-A-Y-E-I-K-K-V-A-Q


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-P-P-K-A-R-T-N-A-R-R-T-G-R-R-V-V-K-K-N-V-A-N-G-N-A-Y-I-K-S-T-F-N-N-T-I-V-S-I-T-D-T-N-G-A-V-I-S-W-A-S-S-G-H-V-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-M-A-A-E-N-A-A-R-K-A-M-D-H-G-M-K-K-V-D-V-F-V-K-G-P-G-S-G-R-E-T-A-I-R-S-L-Q-A-A-G-L-E-I-G-S-I-S-D-V-T-P-Q-P-H-N-G-C-R-P-P-K-R-R-R-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-L-A-G-V-D-L-P-R-N-K-R-M-E-V-A-L-T-Y-I-Y-G-I-G-P-A-R-S-K-Q-L-L-E-E-T-G-I-S-P-D-L-R-T-D-N-L-T-D-E-Q-I-A-A-L-R-D-V-I-E-G-T-W-K-V-E-G-D-L-R-R-Q-V-Q-A-D-I-R-R-K-I-E-I-G-C-Y-Q-G-I-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-K-K-T-I-A-G-K-K-K


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-G-A-I-E-V-E-G-R-I-V-E-P-L-P-N-A-M-F-R-V-E-L-D-N-G-H-K-V-L-A-H-I-S-G-K-M-R-Q-H-Y-I-R-I-L-P-E-D-R-V-V-V-E-L-S-P-Y-D-L-T-R-G-R-I-V-Y-R-Y-K


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-S-N-T-E-N-K-Q-K-R-V-S-V-G-K-D-I-A-T-R-R-R-V-A-R-A-R-R-H-F-R-I-R-K-N-L-R-G-T-P-E-A-P-R-L-V-V-H-R-S-S-R-H-M-H-V-Q-I-I-D-D-V-A-G-H-T-L-A-A-A-S-S-I-E-A-E-V-R-A-T-E-G-D-K-K-A-K-G-A-K-V-G-Q-L-I-A-E-R-A-K-A-A-G-I-E-Q-V-V-F-D-R-A-G-Y-K-Y-H-G-R-V-A-A-L-A-D-A-A-R-E-G-G-L-K-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-E-P-I-T-I-P-S-G-V-E-T-K-I-D-G-Q-L-V-E-V-K-G-P-K-G-T-L-N-V-N-V-P-E-P-I-S-V-A-V-E-D-G-K-I-V-V-T-R-P-D-D-H-R-T-N-R-S-L-H-G-L-S-R-S-L-V-N-N-L-V-V-G-V-T-E-G-Y-T-I-K-M-E-I-F-G-V-G-Y-R-V-A-L-K-G-K-D-L-E-F-S-L-G-Y-S-H-P-V-L-I-E-A-S-E-G-I-T-F-A-V-D-G-N-T-K-L-S-V-S-G-I-D-K-Q-K-V-G-Q-V-A-A-V-I-R-R-L-R-K-D-D-P-Y-K-G-K-G-I-R-Y-E-G-E-Q-I-R-R-K-V-G-K-T-G-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-M-T-D-P-I-A-D-M-L-S-R-V-R-N-A-S-N-A-H-H-D-T-V-S-M-P-S-S-K-I-K-A-N-I-A-E-I-L-K-Q-E-G-Y-I-A-N-Y-T-V-E-D-A-K-V-G-K-T-L-S-L-E-L-K-Y-S-N-T-R-E-R-S-I-A-G-L-R-R-V-S-K-P-G-L-R-V-Y-A-K-S-T-N-L-P-Q-V-L-G-G-L-G-V-A-I-I-S-T-S-Q-G-L-L-T-D-R-Q-A-T-E-K-G-V-G-G-E-V-L-A-Y-V-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-T-E-N-Y-I-P-R-L-K-T-R-Y-Q-D-E-I-R-T-K-L-Q-G-E-F-E-F-E-N-V-M-Q-I-P-G-V-T-K-I-V-V-N-M-G-V-G-D-A-A-R-D-S-K-L-I-N-G-A-I-E-D-L-T-A-I-T-G-Q-K-P-Q-L-R-R-A-K-K-S-I-A-N-F-K-L-R-E-G-M-P-I-G-A-K-V-T-L-R-G-D-R-M-W-E-F-L-D-R-L-L-T-V-A-L-P-R-I-R-D-F-R-G-L-S-D-Q-Q-F-D-G-H-G-N-Y-T-F-G-L-T-E-Q-T-M-F-Y-E-I-D-V-D-K-I-D-R-P-R-G-M-D-I-T-V-V-T-T-A-V-T-D-D-E-G-R-S-L-L-R-E-L-G-F-P-F-K-G-E-D-G-N-R-Q-Q


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-K-V-H-K-G-D-M-V-L-V-I-S-G-P-D-K-G-A-K-G-Q-V-I-A-A-F-P-K-T-E-K-V-L-V-E-G-V-N-R-I-K-K-H-V-A-N-S-A-P-E-R-G-A-E-S-G-G-I-V-T-Q-E-A-P-I-H-V-S-N-V-M-V-I-D-S-D-G-N-P-T-R-V-G-Y-R-F-D-E-N-G-K-K-V-R-V-S-R-R-N-G-K-D-I


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-S-R-L-K-V-A-D-N-T-G-A-R-E-I-L-C-I-R-V-L-G-G-S-T-R-R-F-A-G-I-G-D-V-I-V-A-T-V-K-E-A-T-P-G-G-N-V-K-S-G-E-I-V-K-A-V-I-V-R-T-K-K-E-T-R-R-A-D-G-S-Y-I-S-F-D-E-N-A-A-V-I-I-K-N-D-N-E-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-K-K-F-M-K-I-V-S-L-A-P-E-V-I


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-A-N-V-N-N-Q-E-K-S-T-R-K-V-R-T-G-Y-V-V-S-D-K-M-Q-K-T-I-V-V-E-V-E-D-R-K-Q-H-A-L-Y-G-K-I-L-R-S-A-K-K-V-K-A-H-D-E-E-Q-I-A-G-I-G-D-L-V-R-I-E-E-T-R-P-L-S-K-D-K-N-Y-R-L-I-E-I-V-E-K-A-K


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-I-P-K-R-V-K-Y-R-R-Q-H-R-P-T-R-S-G-I-S-K-G-G-N-R-V-T-F-G-E-Y-G-I-Q-A-L-E-P-A-Y-I-T-N-R-Q-I-E-S-A-R-I-A-I-N-R-H-V-K-R-G-G-K-V-W-I-N-I-F-P-D-R-P-L-T-Q-K-P-L-G-V-R-M-G-S-G-K-G-P-V-E-K-W-V-A-N-I-K-P-G-R-I-L-F-E-M-S-Y-P-D-E-A-T-A-L-E-A-L-R-R-A-G-Q-K-L-P-C-K-V-R-I-V-K-R-E-D-Q-L


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-S-D-N-I-T-S-A-S-A-T-A-R-F-V-R-V-S-P-M-K-A-R-R-V-I-D-L-V-R-G-K-T-V-V-E-A-L-S-I-L-K-Y-A-P-Q-A-A-S-E-P-V-A-K-V-V-A-S-A-A-A-N-A-E-N-N-F-G-L-D-P-R-T-L-V-I-S-E-A-Y-A-N-E-G-P-T-M-K-R-F-Q-P-R-A-Q-G-R-A-F-Q-I-R-K-R-S-S-H-I-T-V-V-V-E-S-Q-K-E-G-A-N


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-A-T-I-A-N-P-R-D-I-I-I-A-P-V-V-S-E-K-S-Y-G-L-M-E-Q-N-V-Y-T-F-F-V-S-T-D-A-N-K-T-Q-I-K-I-A-I-E-E-I-F-G-V-K-V-A-S-V-N-T-V-N-R-A-G-K-R-K-R-S-R-T-G-F-G-T-R-K-A-T-K-R-A-Y-V-T-L-R-E-G-S-D-S-I-D-I-F-N-G-S-V-A


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-R-K-S-A-A-P-K-R-P-V-V-Q-D-P-V-Y-K-S-E-L-V-T-Q-L-V-N-K-I-L-I-G-G-K-K-S-T-A-E-R-I-V-Y-G-A-L-E-I-C-R-E-K-T-G-T-D-P-V-G-T-L-E-K-A-L-G-N-V-R-P-D-L-E-V-R-S-R-R-V-G-G-A-T-Y-Q-V-P-V-D-V-R-P-E-R-A-N-T-L-A-L-R-W-L-V-T-F-T-R-Q-R-R-E-N-T-M-I-E-R-L-A-N-E-L-L-D-A-A-N-G-L-G-A-S-V-K-R-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-Y-R-W


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-Q-Q-L-V-R-K-G-R-H-D-K-S-A-K-V-A-T-A-A-L-K-G-S-P-Q-R-R-G-V-C-T-R-V-Y-T-T-T-P-K-K-P-N-S-A-L-R-K-V-A-R-V-R-L-T-S-G-I-E-V-S-A-Y-I-P-G-E-G-H-N-L-Q-E-H-S-M-V-L-V-R-G-G-R-V-K-D-L-P-G-V-R-Y-K-I-V-R-G-A-L-D-T-Q-G-V-K-D-R-K-Q-A-R-S-R-Y-G-A-K-R-G


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-K-L-T-K-D-E-L-I-E-A-F-K-E-M-T-L-I-E-L-S-E-F-V-K-E-F-E-E-V-F-D-V-T-A-A-A-P-V-A-V-A-A-A-G-A-A-G-G-E-A-A-A-A-E-E-K-D-E-F-D-V-V-L-E-D-A-G-A-K-K-I-G-V-I-K-A-V-R-E-L-V-S-G-L-G-L-K-E-A-K-E-L-V-E-G-A-P-K-A-I-L-E-G-A-N-K-D-D-A-E-A-A-K-A-K-L-E-E-A-G-A-K-V-T-L-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-A-N-P-R-N-E-A-A-L-A-E-L-K-A-R-F-A-E-T-D-T-V-V-L-T-E-Y-R-G-L-T-V-A-Q-T-T-E-L-R-K-A-L-G-F-D-V-Q-Y-S-V-A-K-N-T-L-V-K-I-A-A-N-E-A-G-V-E-G-L-D-D-L-L-T-G-P-T-A-V-A-F-I-K-G-E-A-V-D-T-A-K-V-L-K-K-F-G-E-E-N-K-A-F-V-V-K-G-G-Y-M-D-G-N-A-L-T-A-E-Q-V-N-A-I-A-E-L-D-N-R-E-T-T-L-A-K-L-A-G-A-M-K-G-S-L-A-K-A-A-G-L-F-N-A-P-A-S-Q-V-A-R-L-A-V-A-L-Q-D-K-K-D-A


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-T-Q-P-D-M-S-Q-I-L-A-Q-A-Q-Q-M-Q-A-Q-L-Q-A-A-Q-Q-E-I-L-A-T-T-V-V-G-N-A-G-N-G-L-V-T-V-T-M-A-G-N-G-E-V-S-A-V-T-V-D-P-K-V-V-D-P-E-D-V-E-T-L-Q-D-L-L-L-G-A-F-K-D-A-H-N-K-V-A-N-V-A-E-E-K-M-G-P-L-S-Q-G-M-G-G-L-F


### FUNCTION Involved in cell division ### SEQUENCE -M-P-K-A-R-V-T-K-N-E-T-A-P-V-S-S-N-P-S-A-N-R-T-P-V-K-I-N-S-A-G-T-P-M-W-Y-K-V-I-M-F-A-F-M-I-V-G-L-A-W-L-I-I-N-Y-L-V-G-P-Q-I-P-F-M-A-D-L-G-A-W-N-Y-G-I-G-F-G-L-M-I-I-G-L-L-M-T-M-G-W-R


### FUNCTION Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, ie the esterification of glucose at the C6'' position with the carboxyl group of the C ### SEQUENCE -M-K-T-M-K-K-Y-I-K-T-A-F-F-C-S-M-Y-W-L-I-V-Q-L-N-I-A-N-L-G-T-R-I-P-D-K-Y-F-R-Q-K-Y-I-I-F-K-S-F-N-F-E-K-H-G-K-F-W-N-K-W-F-Y-V-R-K-W-K-H-K-I-L-D-G-H-Q-L-N-Q-N-I-Y-D-Q-R-H-L-M-T-I-N-T-D-E-I-E-K-M-I-I-E-T-K-R-A-E-L-I-H-W-I-S-I-L-P-V-I-I-F-N-K-G-P-R-L-V-K-Y-I-N-I-F-Y-A-M-I-A-N-V-P-I-I-I-V-Q-R-Y-N-R-P-R-L-T-Q-L-L-R-I-L-K-R-R-G-E-R-H-D


### FUNCTION Activates transcription of virulence factors alpha- and beta hemolysin genes ### SEQUENCE -M-Y-V-E-N-S-Y-L-S-K-Q-L-C-F-L-F-Y-V-S-S-K-E-I-I-K-K-Y-T-N-Y-L-K-E-Y-D-L-T-Y-T-G-Y-I-V-L-M-A-I-E-N-D-E-K-L-N-I-K-K-L-G-E-R-V-F-L-D-S-G-T-L-T-P-L-L-K-K-L-E-K-K-D-Y-V-V-R-T-R-E-E-K-D-E-R-N-L-Q-I-S-L-T-E-Q-G-K-A-I-K-S-P-L-A-E-I-S-V-K-V-F-N-E-F-N-I-S-E-R-E-A-S-D-I-I-N-N-L-R-N-F-V-S-K-N-F-D-Y-S-D-K-K


### FUNCTION May be involved in the biosynthesis of molybdopterin ### SEQUENCE -M-G-E-H-Q-N-V-K-L-N-R-T-V-K-A-A-V-L-T-V-S-D-T-R-D-F-D-T-D-K-G-G-Q-C-V-R-Q-L-L-Q-A-D-D-V-E-V-S-D-A-H-Y-T-I-V-K-D-E-K-V-A-I-T-T-Q-V-K-K-W-L-E-E-D-I-D-V-I-I-T-T-G-G-T-G-I-A-Q-R-D-V-T-I-E-A-V-K-P-L-L-T-K-E-I-E-G-F-G-E-L-F-R-Y-L-S-Y-V-E-D-V-G-T-R-A-L-L-S-R-A-V-A-G-T-V-N-N-K-L-I-F-S-I-P-G-S-T-G-A-V-K-L-A-L-E-K-L-I-K-P-E-L-N-H-L-I-H-E-L-T-K


### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-T-E-F-T-H-I-N-Q-Q-G-H-A-K-M-V-D-V-S-D-K-Q-I-T-K-R-T-A-V-A-H-S-S-I-T-V-N-K-T-I-F-K-Q-I-S-N-N-T-N-T-K-G-N-V-L-N-T-A-Q-I-A-G-I-M-A-A-K-N-T-S-T-I-I-P-M-C-H-P-L-P-L-T-G-I-D-V-H-F-S-W-D-E-T-N-A-P-L-Y-T-L-N-I-Q-T-T-V-S-T-T-G-K-T-G-V-E-M-E-A-L-T-A-A-S-A-T-A-L-T-I-Y-D-M-T-K-A-V-D-K-G-M-I-I-G-E-T-Y-L-E-S-K-S-G-G-K-S-G-D-F-Q-R-Q-S-N-Q


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-S-E-R-N-D-R-K-V-Y-V-G-K-V-V-S-D-K-M-D-K-T-I-T-V-L-V-E-T-Y-K-T-H-K-L-Y-G-K-R-V-K-Y-S-K-K-Y-K-T-H-D-E-N-N-S-A-K-L-G-D-I-V-K-I-Q-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-I-V-E-E-S-V-I-I


### FUNCTION Involved in multidrug efflux ### SEQUENCE -M-I-V-N-Y-L-K-H-K-F-Y-N-L-L-T-T-M-V-V-L-F-I-F-V-L-S-G-A-I-F-L-T-F-L-G-F-G-L-Y-G-L-S-R-I-L-I-Y-F-R-L-G-D-F-T-Y-N-R-S-M-Y-D-N-L-L-Y-Y-G-S-Y-I-I-F-G-Y-F-I-I-F-A-V-E-H-L-M-D-Y-F-R-K-M-L-P-E-N-A-Y-F-R-G-A-T-F-H-L-I-S-Y-T-V-A-T-T-L-F-Y-F-I-I-H-L-N-Y-V-Y-I-N-I-D-F-W-V-I-M-V-I-I-G-F-L-Y-V-C-K-L-Q-F-Y-P-E-S-K-N-L-N-N-R-K


### FUNCTION Part of the high-affinity ATP-driven potassium transport  system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex ### SEQUENCE -M-N-T-I-R-N-S-I-C-L-T-I-I-T-M-V-L-C-G-F-L-F-P-L-A-I-T-L-I-G-Q-I-F-F-Y-Q-Q-A-N-G-S-L-I-T-Y-D-N-R-I-V-G-S-K-L-I-G-Q-H-W-T-E-T-R-Y-F-H-G-R-P-S-A-V-D-Y-N-M-N-P-E-K-L-Y-K-N-G-V-S-S-G-G-S-N-E-S-N-G-N-T-E-L-I-A-R-M-K-H-H-V-K-F-G-N-S-N-V-T-I-D-A-A-T-S-S-G-S-G-L-D-P-H-I-T-V-E-N-A-L-K-Q-A-P-R-I-A-D-A-R-H-I-S-T-S-R-V-A-D-L-I-Q-H-R-K-Q-R-G-V-L-T-N-D-Y-V-N-V-L-E-L-N-I-A-L-D-K-M-K-D


### FUNCTION Negative regulator of sigma-B activity Phosphorylates and inactivates its specific antagonist protein, RsbV Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme ### SEQUENCE -M-Q-S-K-E-D-F-I-E-M-R-V-P-A-S-A-E-Y-V-S-L-I-R-L-T-L-S-G-V-F-S-R-A-G-A-T-Y-D-D-I-E-D-A-K-I-A-V-S-E-A-V-T-N-A-V-K-H-A-Y-K-E-N-N-N-V-G-I-I-N-I-Y-F-E-I-L-E-D-K-I-K-I-V-I-S-D-K-G-D-S-F-D-Y-E-T-T-K-S-K-I-G-P-Y-D-K-N-E-N-I-D-F-L-R-E-G-G-L-G-L-F-L-I-E-S-L-M-D-E-V-T-V-Y-K-E-S-G-V-T-I-S-M-T-K-Y-I-K-K-E-Q-V-R-N-N-G-E-R-V-E-I-S


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-A-A-I-K-P-I-T-T-Y-K-G-K-I-V-P-L-F-N-D-N-I-D-T-D-Q-I-I-P-K-V-H-L-K-R-I-S-K-S-G-F-G-P-F-A-F-D-E-W-R-Y-L-P-D-G-S-D-N-P-D-F-N-P-N-K-P-Q-Y-K-G-A-S-I-L-I-T-G-D-N-F-G-C-G-S-S-R-E-H-A-A-W-A-L-K-D-Y-G-F-H-I-I-I-A-G-S-F-S-D-I-F-Y-M-N-C-T-K-N-A-M-L-P-I-V-L-E-K-N-A-R-E-H-L-A-K-Y-V-E-I-E-V-D-L-P-N-Q-T-V-S-S-P-D-K-R-F-H-F-E-I-D-E-T-W-K-N-K-L-V-N-G-L-D-D-I-A-I-T-L-Q-Y-E-S-L-I-E-K-Y-E-K-S-L


### FUNCTION Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide  This quorum sensing system is responsible for the regulation of the expression of virulence factor genes Involved in the proteolytic processing of AgrD, the precursor of AIP ### SEQUENCE -M-N-Y-F-D-N-K-I-D-Q-F-A-T-Y-L-Q-K-R-N-N-L-D-H-I-Q-F-L-Q-V-R-L-G-M-Q-V-L-A-K-N-I-G-K-L-I-V-M-Y-T-I-A-Y-I-L-N-I-F-I-F-T-L-I-T-N-I-S-F-Y-L-I-R-R-Y-A-H-G-A-H-A-P-S-S-F-W-C-Y-I-E-S-I-T-L-F-I-V-L-P-L-L-V-L-H-F-H-I-N-E-T-L-M-M-F-L-A-L-I-S-V-G-V-V-I-K-Y-A-P-A-A-T-K-K-K-P-I-P-A-R-L-V-K-Q-K-R-Y-F-S-I-I-I-S-T-I-L-F-I-I-T-L-F-V-K-E-P-Y-T-Q-F-I-Q-L-G-I-I-I-Q-A-I-T-L-L-P-I-Y-Y-S-K-E-D


### FUNCTION Lyses erythrocytes and many other mammalian cells ### SEQUENCE -M-A-Q-D-I-I-S-T-I-S-D-L-V-K-W-I-I-D-T-V-N-K-F-T-K-K


### FUNCTION Potent plasminogen activator that converts plasminogen into plasmin It forms a 11 complex with plasmin, which in turn activates other plasminogen molecules ### SEQUENCE -M-L-K-R-S-L-L-F-L-T-V-L-L-L-L-F-S-F-S-S-I-T-N-E-V-S-A-S-S-S-F-D-K-G-K-Y-K-K-G-D-D-A-S-Y-F-E-P-T-G-P-Y-L-M-V-N-V-T-G-V-D-G-K-G-N-E-L-L-S-P-H-Y-V-E-F-P-I-K-P-G-T-T-L-T-K-E-K-I-E-Y-Y-V-E-W-A-L-D-A-T-A-Y-K-E-F-R-V-V-E-L-D-T-S-A-K-I-E-V-T-Y-Y-D-K-N-K-K-K-E-E-T-K-S-F-P-I-T-E-K-G-F-V-V-P-D-L-S-E-H-I-K-N-P-G-F-N-L-I-T-K-V-V-I-E-K-K


### FUNCTION Signal transduction protein, which is a major regulator of staphylococcal pathogenesis Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors Up-regulates the expression of most toxins and genes known to be necessary for biofilm formation ### SEQUENCE -M-K-K-L-Y-T-S-Y-G-T-Y-G-F-L-H-Q-I-K-I-N-N-P-T-H-Q-L-F-Q-F-S-A-S-D-T-S-V-I-F-E-E-T-D-G-E-T-V-L-K-S-P-T-K-Y-D-V-I-K-E-I-G-E-F-S-E-H-H-F-Y-C-A-I-F-I-P-S-T-E-D-H-A-Y-Q-L-E-K-K-L-I-S-V-D-D-N-F-R-N-F-G-G-F-K-S-Y-R-L-L-R-P-A-K-G-T-T-Y-K-I-Y-F-G-F-A-D-R-H-A-Y-E-D-F-K-Q-S-D-A-F-N-D-H-F-S-K-D-A-L-S-H-Y-F-G-S-S-G-Q-H-S-S-Y-F-E-R-Y-L-Y-P-I-K-E


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-S-I-I-L-V-M-I-G-G-G-F-G-A-I-T-R-S-A-I-T-D-Y-F-N-H-K-F-T-S-K-L-P-I-A-T-L-I-V-N-L-V-G-S-F-L-I-G-L-N-I-G-L-S-I-S-I-S-W-F-P-A-F-F-V-T-G-F-L-G-G-L-T-T-F-S-T-L-A-K-E-L-T-L-M-M-T-P-K-F-N-I-N-L-F-L-N-Y-S-L-L-Q-F-I-I-G-F-I-A-C-Y-I-G-Y-H-I


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-H-R-Q-F-L-S-S-R-C-Q-N-L-F-F-K-F-K-L-L-L-F-E-V-N-Q-M-Q-Y-V-Y-I-F-I-G-G-A-L-G-A-L-L-R-Y-L-I-S-F-L-N-T-D-G-G-F-P-I-G-T-L-I-A-N-L-T-G-A-F-V-M-G-L-L-T-A-L-T-I-A-F-F-S-N-H-P-T-L-K-K-A-I-T-T-G-F-L-G-A-L-T-T-F-S-T-F-Q-L-E-L-I-H-M-F-D-H-Q-Q-F-I-T-L-L-L-Y-A-V-T-S-Y-V-F-G-I-L-L-C-Y-V-G-I-K-L-G-G-G-L-S