### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-S-E-K-T-Y-P-M-T-L-A-E-K-E-Q-L-E-Q-E-L-E-E-L-K-L-V-R-R-P-E-V-I-E-R-I-K-I-A-R-S-Y-G-D-L-S-E-N-S-E-Y-E-A-A-K-D-E-Q-A-F-V-E-G-Q-I-S-S-I-E-T-K-I-R-Y-A-E-I-V-D-S-D-A-V-A-K-N-E-V-A-I-G-K-T-V-I-V-R-E-V-G-T-N-D-E-D-T-Y-S-I-V-G-A-A-G-A-D-V-F-A-G-K-I-S-N-E-S-P-I-A-Q-A-L-I-G-K-K-T-G-D-K-V-M-I-E-S-P-A-G-S-Y-Q-V-E-I-V-K-V-K-K-T-K


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-N-I-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-I-N-I-M-G-F-T-K-E-F-N-A-R-T-A-D-Q-A-G-M-I-I-P-V-V-I-S-V-Y-E-D-K-S-F-D-F-V-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-D-K-G-S-G-E-P-N-K-T-K-V-A-S-V-T-R-A-Q-V-Q-E-I-A-E-T-K-M-P-D-L-N-A-A-N-L-E-S-A-M-R-M-I-E-G-T-A-R-S-M-G-F-T-V-T-D


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-N-A-I-V-E-K-A-K-E-R-F-E-Q-S-H-Q-S-L-A-R-E-F-G-S-I-R-A-G-R-A-N-A-S-L-L-D-R-I-E-V-E-Y-Y-G-V-P-T-P-L-N-Q-L-A-S-I-T-V-P-E-A-R-V-L-L-V-S-P-F-D-K-S-S-L-K-D-I-E-H-A-I-N-A-S-D-I-G-I-N-P-A-N-D-G-S-V-I-R-L-V-I-P-A-L-T-E-E-T-R-K-E-L-A-K-E-V-K-K-V-G-E-N-A-K-V-A-I-R-N-I-R-R-D-A-M-D-E-A-K-K-Q-E-K-I-K-E-I-T-E-D-E-L-K-S-L-E-K-D-I-Q-K-V-T-D-E-A-V-K-H-I-D-S-M-T-A-N-K-E-K-E-L-L-E-V


### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-R-A-I-F-A-G-G-C-F-W-C-M-V-Q-P-F-E-E-Q-D-G-I-L-S-V-R-S-G-Y-T-G-G-H-V-V-N-P-T-Y-E-Q-V-C-S-K-M-T-G-H-T-E-A-V-E-I-I-F-D-E-S-K-I-S-Y-A-D-L-V-E-I-Y-W-R-Q-T-D-P-T-D-S-F-G-Q-F-E-D-R-G-D-N-Y-R-P-V-I-F-Y-F-D-E-Q-Q-R-K-I-A-E-Q-S-K-A-N-L-Q-A-S-G-H-F-N-R-P-I-V-T-T-I-E-A-A-Q-P-F-Y-E-A-E-K-D-H-Q-A-F-Y-R-K-N-P-E-R-Y-A-R-S-S-A-I-R-H-H-F-L-K-E-N-W-S


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-Y-I-E-M-I-D-E-T-N-Q-V-S-E-E-I-K-N-Q-T-L-D-I-L-E-F-A-A-Q-K-T-G-K-E-D-K-E-M-A-V-T-F-V-T-N-E-R-S-H-E-L-N-L-K-Y-R-D-T-N-R-P-T-D-V-I-S-L-E-Y-K-P-E-S-S-L-S-F-D-E-E-D-L-A-D-D-P-D-L-A-E-V-L-T-E-F-D-A-Y-I-G-E-L-F-I-S-V-D-K-A-R-E-Q-A-Q-E-Y-G-H-S-F-E-R-E-M-G-F-L-A-V-H-G-F-L-H-I-N-G-Y-D-H-Y-T-P-Q-E-E-K-E-M-F-S-L-Q-E-E-I-L-D-A-Y-G-L-K-R


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-V-K-A-Q-G-N-V-V-A-Q-N-K-K-A-R-H-D-Y-E-I-L-E-T-Y-E-A-G-I-V-L-T-G-T-E-I-K-S-V-R-A-A-R-I-T-L-K-D-G-F-A-Q-V-K-N-G-E-V-W-L-N-N-V-H-I-T-P-Y-E-Q-G-N-I-W-N-Q-D-P-D-R-T-R-K-L-L-L-K-K-R-E-I-A-K-L-D-N-E-L-K-G-T-G-M-T-L-V-P-L-K-V-Y-L-K-N-G-F-A-K-V-L-I-G-L-A-K-G-K-H-D-Y-D-K-R-E-S-I-K-R-R-E-Q-D-R-D-I-K-R-Q-M-K-Q-F-N-G-R


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-K-N-Y-I-A-T-I-E-D-Y-P-Q-E-G-V-T-F-R-D-I-S-P-L-M-A-N-G-N-A-Y-S-Y-A-I-R-E-I-V-Q-Y-A-T-D-K-K-I-D-M-I-V-G-P-E-A-R-G-F-I-V-G-C-P-V-A-Y-E-L-G-V-G-F-A-P-V-R-K-P-G-K-L-P-R-E-V-I-E-A-H-Y-E-K-E-Y-G-I-D-T-L-T-M-H-A-D-A-I-K-P-G-Q-R-V-L-I-V-D-D-L-L-A-T-G-G-T-V-K-A-T-I-E-M-I-E-R-L-G-G-I-V-A-G-C-A-F-L-I-E-L-D-G-L-D-G-R-Q-A-I-E-G-Y-D-T-K-V-L-M-N-F-P-G


### FUNCTION CRISPR  Functions as a ssRNA-specific endoribonuclease Involved in the integration of spacer DNA into the CRISPR cassette ### SEQUENCE -M-R-M-I-L-M-F-D-M-P-T-D-T-A-E-E-R-K-A-Y-R-K-F-R-K-F-L-L-S-E-G-F-I-M-H-Q-F-S-V-Y-S-K-L-L-L-N-N-S-A-N-T-A-M-I-A-R-L-K-E-N-N-P-K-K-G-N-I-T-L-L-T-V-T-E-K-Q-F-A-R-M-I-Y-L-N-G-E-R-D-T-S-I-A-N-S-D-S-R-L-V-F-L-G-E-A-F-P-D-E-T


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-E-E-F-T-I-Y-T-G-T-T-V-P-L-M-N-D-N-I-D-T-D-Q-I-L-P-K-Q-F-L-K-L-I-D-K-K-G-F-G-K-Y-L-M-Y-E-W-R-Y-L-D-N-N-Y-T-E-N-P-D-F-I-F-N-Q-P-E-Y-R-E-A-S-I-L-I-T-G-D-N-F-G-A-G-S-S-R-E-H-A-A-W-A-L-A-D-Y-G-F-K-V-I-V-A-G-S-F-G-D-I-H-Y-N-N-D-L-N-N-G-I-L-P-I-I-Q-P-K-E-V-R-D-K-L-A-K-L-K-P-T-D-E-V-T-V-N-L-F-E-Q-K-I-Y-S-P-V-G-D-F-S-F-D-I-D-G-E-W-K-H-K-L-L-N-G-L-D-D-I-G-I-T-L-Q-Y-E-D-L-I-A-Q-Y-E-Q-N-R-P-S-Y-W-H


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-P-L-I-Q-S-L-T-E-S-Q-L-R-T-D-I-P-N-F-R-P-G-D-T-V-R-V-H-A-K-V-V-E-G-N-R-E-R-V-Q-I-F-E-G-V-V-I-S-R-K-G-Q-G-I-S-E-M-Y-T-V-R-K-I-S-S-G-V-G-V-E-R-T-F-P-T-H-T-P-R-V-E-K-I-E-V-T-R-H-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-Q-G-K-A-A-R-I-K-E-V-R-Q


### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-V-T-L-F-L-S-P-S-C-T-S-C-R-K-A-R-A-W-L-N-R-H-D-V-V-F-Q-E-H-N-I-M-T-S-P-L-S-R-D-E-L-L-K-I-L-S-Y-T-E-N-G-T-E-D-I-I-S-T-R-S-K-V-F-Q-K-L-D-I-D-V-D-E-L-S-V-S-E-L-I-N-L-I-S-K-N-P-S-L-L-R-R-P-I-I-M-D-N-K-R-M-Q-I-G-F-N-E-D-E-I-R-A-F-L-P-R-D-Y-R-K-Q-E-L-R-Q-A-T-I-R-A-E-V-E-G-E-D-D


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-A-E-L-N-V-K-Q-N-N-R-N-S-A-Q-K-S-A-M-R-S-A-I-K-A-F-E-A-N-P-N-E-E-L-F-R-A-A-S-S-S-I-D-K-A-K-S-K-G-L-I-H-K-N-K-A-S-R-D-K-A-R-L-A-S-K-L-A-K


### FUNCTION Covalent carrier of the coenzyme of citrate lyase ### SEQUENCE -M-D-I-K-Q-T-A-V-A-G-S-L-E-S-S-D-I-M-V-T-V-N-P-S-D-V-Q-G-I-T-V-Q-L-E-S-S-V-E-K-Q-F-G-Q-Q-I-R-K-V-I-E-E-T-L-K-H-L-G-V-K-A-A-S-V-E-A-V-D-K-G-A-L-D-C-T-I-K-A-R-T-I-T-A-V-H-R-A-A-Q-V-E-V-Y-D-W-K-E-I-D-S-W-N-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-N-I-E-N-I-I-A-E-I-K-E-A-S-I-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-A-A-G-A-A-G-G-E-E-A-A-A-K-D-S-F-D-I-E-L-T-A-G-G-D-K-K-V-A-V-I-K-V-V-R-E-I-T-G-E-G-L-K-E-A-K-G-L-V-D-N-A-P-S-V-L-K-E-G-V-A-A-A-E-A-E-E-L-K-A-K-L-E-E-A-G-A-T-V-T-L-K


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-E-A-S-I-A-K-K-A-E-L-V-D-A-V-A-E-K-M-K-A-A-V-S-I-V-V-V-D-S-R-G-L-T-V-E-Q-D-T-V-L-R-R-N-L-R-E-S-A-V-E-F-K-V-I-K-N-S-I-L-R-R-A-A-E-K-A-G-L-E-G-F-D-D-I-F-T-G-P-S-A-V-A-F-S-N-E-D-V-V-A-P-A-K-I-I-N-D-F-A-K-D-A-E-A-L-E-I-K-G-G-A-I-E-G-A-V-S-T-K-E-E-I-Q-A-L-A-A-L-P-N-R-E-G-L-L-S-M-L-L-S-V-L-Q-A-P-V-R-N-V-A-Y-A-V-K-A-V-A-E-S-K-D-E-D-A-A


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-S-E-F-L-N-T-H-N-A-S-I-L-L-S-A-V-N-K-S-H-Y-P-Q-D-D-L-P-E-I-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-L-L-G-R-K-N-L-A-R-T-S-S-K-P-G-K-T-Q-S-L-N-F-Y-N-I-D-D-K-L-R-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-K-E-R-A-K-W-G-K-M-I-E-E-Y-L-T-S-R-E-N-L-R-A-V-V-S-L-V-D-F-R-H-D-P-S-S-D-D-V-Q-M-Y-D-F-L-K-Y-Y-E-I-P-V-I-L-V-A-T-K-A-D-K-V-P-R-G-K-W-N-K-Q-E-S-A-I-K-K-K-L-D-F-D-S-N-D-A-F-I-I-F-S-S-V-D-R-T-G-L-D-T-S-W-D-A-I-L-E-S-L


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-K-Y-F-N-V-G-K-I-V-N-T-Q-G-L-R-G-E-V-R-V-L-S-V-T-D-F-A-D-E-R-F-K-K-G-S-Q-L-A-L-F-D-K-K-D-H-F-A-M-T-V-E-I-A-S-H-R-K-H-K-N-F-D-I-V-K-F-K-G-L-Y-H-I-N-D-V-E-K-Y-R-D-F-T-L-K-V-T-E-D-H-L-A-D-L-E-D-G-E-F-Y-Y-H-E-I-I-G-L-D-V-Y-E-N-D-I-L-I-G-Q-V-K-E-I-L-Q-P-G-A-N-D-V-W-V-V-K-R-K-G-K-K-D-L-L-L-P-Y-I-P-S-V-I-L-K-V-D-V-P-N-G-R-I-D-V-T-V-L-E-G-L-D-D-E-N


### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide  operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-K-T-K-E-I-V-D-G-V-T-M-K-R-A-I-T-R-M-T-Y-E-I-I-E-R-N-K-N-L-D-N-I-V-L-A-G-I-K-T-R-G-V-F-I-A-R-R-I-Q-E-R-L-K-Q-I-E-G-L-D-V-P-L-G-E-L-D-T-K-S-F-R-D-D-V-K-V-E-E-N-T-T-E-M-P-V-D-I-T-N-R-D-V-I-L-V-D-D-V-L-Y-T-G-R-T-I-R-A-A-I-D-N-I-V-N-L-G-R-P-A-R-V-S-L-A-V-L-V-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-S-S-E-E-I-V-V-N-M-V-E-I-D-D-K-D-N-V-L-L-L-A-K-E-D-S-L


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-T-Y-A-I-I-K-T-G-G-K-Q-V-K-V-E-V-D-Q-A-I-Y-V-E-K-L-D-V-E-A-G-A-E-V-T-F-D-Q-V-V-L-V-G-G-D-K-T-V-V-G-T-P-I-V-Q-G-A-T-V-V-G-T-V-E-K-Q-G-K-Q-K-K-V-V-T-Y-K-Y-K-P-K-K-G-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-K-A-I-N-A


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-G-G-V-V-S-R-K-R-R-K-R-V-L-K-L-A-K-G-Y-Y-G-A-K-H-I-L-F-R-T-A-K-E-Q-V-M-N-S-Y-Y-Y-A-Y-R-D-R-R-Q-R-K-R-D-F-R-K-L-W-I-T-R-I-N-A-A-A-R-M-N-G-L-S-Y-S-Q-L-M-H-G-L-K-L-A-E-V-E-V-N-R-K-M-L-A-D-L-A-V-N-D-A-A-A-F-T-V-L-A-D-A-A-K-E-K-L-G-K


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-N-I-A-K-K-D-L-F-I-N-N-E-I-R-V-R-E-V-R-L-I-G-L-D-G-E-Q-L-G-I-K-P-L-A-Q-A-Q-A-I-A-D-D-A-N-V-D-L-V-L-I-Q-P-Q-A-T-P-P-V-A-R-I-M-D-Y-G-K-F-K-F-E-Y-Q-K-K-Q-K-E-Q-R-K-K-Q-S-V-V-T-I-K-E-V-R-L-S-P-V-I-D-K-G-D-F-E-T-K-L-R-N-G-R-K-F-L-E-K-G-N-K-V-K-V-S-I-R-F-K-G-R-M-I-T-H-K-E-I-G-A-K-V-L-A-D-F-A-E-A-T-Q-D-I-A-I-I-E-Q-R-A-K-M-D-G-R-Q-M-F-M-Q-L-A-P-I-P-D-K-K


### FUNCTION Folate-binding protein that interacts with the energy-coupling factor ### SEQUENCE -M-N-T-M-F-K-S-P-K-L-S-P-Q-R-L-V-T-L-A-M-L-I-A-L-A-F-A-I-G-K-L-S-I-P-I-I-P-Q-Q-L-I-I-S-P-T-F-I-V-N-V-M-I-G-M-I-G-G-P-I-W-A-F-I-S-L-A-I-L-D-I-V-D-N-L-S-S-G-A-G-N-F-I-I-W-W-T-L-L-E-A-V-Q-G-L-F-Y-G-L-F-F-Y-Q-K-S-L-S-W-T-N-K-K-D-W-L-H-V-T-I-A-T-A-I-I-M-L-I-G-S-F-I-F-T-P-L-L-V-Q-I-Y-Y-G-V-P-F-W-A-Q-F-A-A-G-R-W-L-K-I-F-E-I-P-I-R-I-L-V-T-M-A-I-M-P-Q-L-Q-R-I-P-E-L-R-K-L-A-N-F-K


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-L-Y-P-T-P-I-A-K-L-I-E-S-F-T-K-L-P-G-I-G-I-K-T-A-T-R-L-A-F-Y-T-I-G-M-S-D-E-D-V-N-N-F-A-K-N-L-L-A-A-K-R-E-L-T-Y-C-S-V-C-G-N-L-T-D-D-D-P-C-N-I-C-T-D-E-S-R-D-R-S-T-V-L-V-V-E-D-S-K-D-V-S-A-M-E-K-I-Q-E-Y-H-G-L-Y-H-V-L-H-G-L-I-S-P-M-N-G-I-G-P-D-D-I-N-L-K-S-L-L-T-R-L-R-D-N-S-D-I-H-E-V-I-I-A-T-N-A-T-A-D-G-E-A-T-A-M-Y-I-S-R-V-L-K-P-A-G-I-T-V-T-R-L-A-R-G-L-A-V-G-S-D-I-E-Y-A-D-E-V-T-L-L-R-A-I-E-N-R-T-E-L


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-S-N-K-K-K-T-F-E-E-N-L-Q-D-L-E-E-I-V-N-Q-L-E-T-G-E-I-P-L-E-E-A-I-T-Q-F-Q-K-G-M-A-L-S-K-D-L-Q-K-T-L-E-S-A-E-K-T-L-V-K-V-M-Q-A-D-G-S-E-A-E-M-D-E-L


### FUNCTION Cell division protein that is part of the divisome complex and is recruited early to the Z-ring Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments Its function overlaps with FtsA ### SEQUENCE -M-A-L-R-D-S-F-N-K-I-I-S-Y-F-D-T-D-E-V-S-E-V-E-E-P-A-V-A-S-V-K-R-Q-Q-D-A-A-Q-P-A-S-Q-Q-Q-K-A-Q-S-H-Q-Y-H-Q-S-A-S-R-P-S-Q-Q-Q-V-Q-S-G-Q-N-R-R-S-G-E-E-N-I-H-S-L-P-T-R-R-Q-S-H-N-Q-Q-P-A-Q-E-K-T-T-I-A-L-K-L-P-R-K-Y-E-D-A-E-E-I-V-D-L-L-I-R-N-E-C-V-L-I-D-F-Q-Y-M-L-E-A-Q-A-R-R-C-L-D-F-I-D-G-A-S-K-V-L-A-G-N-L-Q-K-V-G-A-S-M-Y-L-L-T-P-I-N-V-I-V-D-A-E-E-M-T-L-A-A-N-G-Q-D-V-S-F-N-Y-D-M-K-R-R


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-M-L-K-P-S-I-D-T-L-L-D-K-V-P-S-K-Y-S-L-V-I-L-Q-A-K-R-A-H-E-L-E-S-G-A-T-P-T-Q-A-F-T-S-V-K-P-T-L-Q-A-L-E-E-I-E-A-G-N-V-V-I-H-P-D-P-E-A-K-R-A-A-V-R-A-R-A-E-A-E-R-I-A-K-E-E-E-E-R-K-I-K-E-Q-I-A-K-E-K-E-E-E-G-E-K-I


### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-T-K-E-V-T-V-E-S-F-E-L-D-H-I-A-V-K-A-P-Y-V-R-L-I-S-E-E-F-G-P-K-G-D-L-I-T-N-F-D-I-R-L-V-Q-P-N-E-D-S-I-P-T-A-G-L-H-T-I-E-H-L-L-A-K-L-I-R-Q-R-I-D-G-M-I-D-C-S-P-F-G-C-R-T-G-F-H-L-I-M-W-G-K-H-T-T-T-Q-I-A-T-V-I-K-A-S-L-E-E-I-A-N-T-I-S-W-K-D-V-P-G-T-T-I-E-S-C-G-N-Y-K-D-H-S-L-F-S-A-K-E-W-A-K-L-I-L-K-Q-G-I-S-D-D-P-F-E-R-H-L-V


### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-A-S-I-M-Y-T-P-K-D-I-F-E-Q-E-F-K-S-S-M-R-G-Y-D-K-K-E-V-D-E-F-L-D-D-I-I-K-D-Y-E-T-Y-I-S-T-I-E-E-L-R-Q-E-N-T-R-L-K-E-E-V-K-Q-A-K-K-R-Q-E-A-A-Q-T-T-V-S-P-A-A-S-V-S-S-S-R-V-A-T-T-A-T-N-F-D-I-L-K-R-I-S-R-L-E-K-E-V-F-G-K-Q-I-T-E


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-S-N-H-R-I-E-R-V-G-M-E-I-K-R-E-V-N-E-I-L-Q-K-K-V-R-D-P-R-V-Q-G-V-T-I-T-D-V-Q-M-S-G-D-L-S-L-A-K-V-Y-Y-T-I-M-S-D-L-A-S-D-N-Q-K-V-Q-I-G-L-E-K-A-K-G-T-I-K-R-E-L-G-K-N-L-T-M-Y-K-I-P-D-L-T-F-I-K-D-E-S-I-E-Y-G-N-K-I-D-Q-M-L-R-D-L-E-K-R-N


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-C-K-E-G-N-T-I-A-T-L-V-D-I-V-R-P-V-V-A-P-V-I-P-K-P-F-E-L-V-D-I-E-Y-E-K-L-G-G-N-Y-V-L-S-I-L-V-D-K-P-E-G-I-T-V-E-D-T-A-D-L-T-D-I-I-S-P-L-L-D-T-I-K-P-D-P-F-P-E-Q-Y-M-L-E-I-S-S-P-G-L-E-R-P-L-K-T-A-Q-S-L-M-N-A-V-G-H-Y-I-N-V-S-L-Y-Q-A-I-D-K-V-K-V-F-E-G-D-L-T-A-F-D-G-E-T-L-K-M-T-Y-L-D-K-T-Q-Q-K-T-V-T-I-P-Y-K-M-V-A-K-A-R-L-A-V-K-L


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-M-N-M-Q-N-M-M-K-Q-A-Q-K-L-Q-K-Q-M-E-K-K-Q-S-E-L-A-S-M-T-F-V-G-K-S-A-Q-D-L-V-V-A-T-F-T-G-N-K-K-L-V-S-I-D-F-K-E-A-V-V-D-P-D-D-R-E-T-L-Q-D-M-T-V-Q-A-I-N-D-A-L-G-Q-I-E-D-A-T-Q-K-T-M-G-A-F-A-G-K-L-P-F


### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-F-Y-Q-E-T-K-D-S-S-P-R-R-E-Q-T-K-T-L-Y-L-D-I-D-A-Q-T-E-L-D-G-R-I-Q-A-R-Q-L-V-E-E-K-I-A-Y-N-I-E-L-I-E-L-L-S-D-K-H-L-E-Y-E-K-E-T-G-A-F-Q-L-T-E-F


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-N-R-A-P-K-R-E-V-L-P-D-P-L-Y-N-S-K-L-V-T-R-L-I-N-R-I-M-L-D-G-K-R-G-T-A-A-S-I-V-Y-G-A-F-E-Q-I-K-E-A-T-G-N-D-A-L-E-V-F-E-Q-A-M-E-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-S-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-T-A-S-R-T-R-G-E-H-T-M-K-D-R-L-A-K-E-I-L-D-A-S-N-N-T-G-A-S-V-K-K-R-E-D-T-H-R-M-A-E-A-N-R-A-F-A-H-F-R-W


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-A-Y-R-V-K-S-D-K-D-F-Q-A-I-F-T-E-G-R-S-V-A-N-R-K-F-V-V-Y-S-L-E-K-D-Q-S-H-Y-R-V-G-L-S-V-G-K-R-L-G-N-A-V-V-R-N-A-I-K-R-K-L-R-H-V-L-M-E-L-G-P-Y-L-G-T-Q-D-F-V-V-I-A-R-K-G-V-E-E-L-D-Y-S-T-M-K-K-N-L-V-H-V-L-K-L-A-K-L-Y-Q-E-G-S-I-R-E-K-E-I


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-N-E-I-I-K-Q-Y-A-R-H-D-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-W-E-I-N-H-L-N-E-H-I-K-Q-H-K-K-D-H-A-T-Y-R-G-L-M-K-K-I-G-H-R-R-N-L-L-A-Y-L-R-R-T-D-V-N-R-Y-R-D-L-I-S-S-L-G-L-R-R


### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-E-L-E-V-F-A-G-Q-E-K-S-E-L-S-M-I-E-V-A-R-A-I-L-E-E-R-G-R-D-K-E-M-Y-F-S-D-L-V-N-A-I-Q-V-Y-L-E-K-S-D-A-D-I-R-E-A-L-P-F-F-Y-S-D-L-N-T-D-G-S-F-I-P-L-G-E-N-K-W-G-L-R-S-W-Y-G-I-D-E-I-D-E-E-I-V-T-L-E-E-D-E-D-G-A-P-K-H-K-R-K-R-V-N-A-F-M-D-G-D-E-D-A-I-D-Y-S-D-D-D-P-E-D-E-S-F-N-T-A-E-E-D-T-E-Y-D-E-E-D-P-D-D-E-K-S-E-V-E-S-Y-D-S-E-I-N-E-I-I-P-D-E-D-L-D-E-N-V-D-L-D-E-E-D-D-D-Y-S-D-D-E-E-D-E-E-G-E


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-T-K-L-I-V-G-L-G-N-P-G-S-K-Y-H-E-T-K-H-N-V-G-F-M-A-L-D-R-I-V-K-P-L-N-V-Q-F-T-E-N-K-T-F-K-A-E-T-V-A-T-F-I-N-G-E-K-I-Y-F-I-K-P-T-T-F-M-N-A-S-G-L-A-V-R-A-F-L-A-Y-Y-N-L-T-V-E-D-L-I-V-I-Y-D-D-L-D-M-E-V-G-K-I-R-F-R-Q-K-G-S-A-G-G-H-N-G-I-K-S-I-I-K-E-I-G-T-Q-E-F-D-R-I-K-I-G-I-G-R-P-K-D-K-M-T-V-V-N-Y-V-L-G-K-F-D-K-K-D-E-I-T-I-F-N-T-L-D-K-V-D-K-A-V-N-Y-Y-L-Q-T-K-N-F-E-Q-T-M-Q-K-F-N-G


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-Q-D-V-K-G-K-G-K-K-G-E-V-K-E-V-P-T-G-Y-A-Q-N-F-L-L-K-K-N-L-A-K-E-A-T-T-Q-A-I-G-E-L-K-G-K-Q-K-S-E-E-K-A-Q-A-E-I-L-A-Q-A-K-E-L-K-T-Q-L-E-S-E-T-T-R-V-Q-F-I-E-K-V-G-P-D-G-R-T-F-G-S-I-T-A-K-K-I-A-E-E-L-Q-K-Q-Y-G-I-K-I-D-K-R-H-I-D-L-D-H-T-I-R-A-I-G-K-V-E-V-P-V-K-L-H-K-Q-V-S-S-Q-I-K-L-D-I-K-E-A


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-D-Y-I-K-G-K-L-S-K-I-T-A-K-F-I-V-V-E-T-A-G-L-G-Y-M-I-Y-V-A-N-P-Y-S-F-S-G-Y-V-N-Q-E-V-T-I-Y-L-H-Q-V-I-R-D-D-A-H-L-L-F-G-F-H-T-E-N-E-K-E-I-F-L-N-L-I-S-V-S-G-I-G-P-T-T-A-L-A-I-I-A-V-D-D-N-E-G-L-V-S-A-I-D-N-S-D-I-K-Y-L-T-K-F-P-K-I-G-K-K-T-A-Q-Q-M-I-L-D-L-S-G-K-F-V-E-A-S-G-E-S-A-T-S-R-K-V-S-S-E-Q-N-S-N-L-E-E-A-M-E-A-L-L-A-L-G-Y-K-A-T-E-L-K-K-V-K-A-F-F-E-G-T-N-E-T-V-E-Q-Y-I-K-S-S-L-K-M-L-M-K


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-N-V-V-L-I-G-R-L-T-R-D-V-E-L-R-Y-T-P-S-N-I-A-N-A-T-F-N-L-A-V-N-R-N-F-K-N-A-A-G-D-R-E-A-D-F-I-N-C-V-M-W-R-Q-Q-A-E-N-L-A-N-W-T-K-K-G-M-L-I-G-I-T-G-R-I-Q-T-R-S-Y-E-N-Q-Q-G-Q-R-I-Y-V-T-E-V-V-A-D-S-F-Q-I-L-E-K-R-D-N-S-T-N-Q-A-S-M-D-D-Q-L-P-P-S-F-G-N-S-Q-P-M-D-I-S-D-D-D-L-P-F


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-K-P-R-K-S-K-V-E-K-S-D-S-P-A-L-N-I-G-Y-N-S-H-R-K-V-H-T-K-L-S-A-P-Q-K-R-G-V-A-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-F-A-R-V-R-L-S-N-L-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-T-A-G-V-A-D-R-K-Q-G-R-S-K-Y-G-A-K-R-P-K-G


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-N-Q-A-P-K-R-E-V-L-P-D-P-L-Y-N-S-K-I-V-T-R-L-I-N-R-V-M-L-D-G-K-R-G-T-A-A-T-I-V-Y-D-A-F-E-A-I-K-E-A-T-G-T-D-A-L-E-V-F-E-T-A-M-E-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-S-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-N-A-S-R-A-R-G-E-H-T-M-K-D-R-L-A-K-E-I-M-D-A-A-N-N-T-G-A-S-V-K-K-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-F-R-W


### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-F-Y-Q-E-T-K-E-R-N-P-R-R-E-Q-T-K-T-L-Y-V-T-I-D-A-A-N-E-L-E-G-R-I-A-A-R-K-L-V-E-E-N-T-A-Y-N-I-E-F-I-E-L-L-S-D-K-H-L-E-Y-E-K-E-T-G-V-F-E-L-T-E-F


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-F-Q-K-Q-Q-K-L-V-E-Q-Y-A-E-L-R-R-E-L-K-E-K-G-D-Y-E-A-L-R-K-L-P-K-D-S-N-P-N-R-L-K-N-R-D-L-I-D-G-R-P-H-A-Y-M-R-K-F-G-M-S-R-I-N-F-R-N-L-A-Y-K-G-Q-I-P-G-I-K-K-A-S-W


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Q-Q-R-R-G-G-F-K-R-R-K-K-V-D-Y-I-A-A-N-K-I-E-Y-V-D-Y-K-D-T-E-L-L-S-R-F-V-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-N-Q-R-K-V-T-T-A-I-K-R-A-R-V-M-A-L-M-P-Y-V-N-E-D


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-K-I-S-E-E-E-V-R-H-V-A-N-L-S-K-L-R-F-S-D-Q-E-T-K-E-F-A-S-S-L-S-K-I-V-D-M-I-E-L-L-N-E-V-D-T-E-G-V-P-V-T-T-T-M-A-D-R-K-T-V-M-R-E-D-I-A-Q-P-G-H-N-R-D-D-L-F-K-N-V-P-Q-H-Q-D-Y-Y-I-K-V-P-A-I-L-E-D-G-G-D-A


### FUNCTION Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate  to yield ADP ### SEQUENCE -M-T-Y-K-D-Y-T-G-L-D-R-T-E-L-L-S-K-V-R-H-M-M-S-D-K-R-F-N-H-V-L-G-V-E-R-A-A-I-E-L-A-E-R-Y-G-Y-D-K-E-K-A-G-L-A-A-L-L-H-D-Y-A-K-E-L-S-D-D-E-F-L-R-L-I-D-K-Y-Q-P-D-P-D-L-K-K-W-G-N-N-I-W-H-G-L-V-G-I-Y-K-I-Q-E-D-L-A-I-K-D-Q-D-I-L-A-A-I-A-K-H-T-V-G-S-A-Q-M-S-T-L-D-K-I-V-Y-V-A-D-Y-I-E-H-N-R-D-F-P-G-V-E-E-A-R-E-L-A-K-V-D-L-N-K-A-V-A-Y-E-T-A-R-T-V-A-F-L-A-S-K-A-Q-P-I-Y-P-K-T-I-E-T-Y-N-A-Y-I-P-Y-L-D


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-K-C-G-Y-N-K-S-S-V-V-D-S-R-Q-A-E-E-G-T-T-I-R-R-R-R-E-C-E-K-C-G-N-R-F-T-T-F-E-R-L-E-E-L-P-L-L-V-I-K-K-D-G-T-R-E-Q-F-S-R-D-K-I-L-N-G-I-I-Q-S-A-Q-K-R-P-V-S-S-E-D-I-E-N-C-I-L-R-I-E-R-K-I-R-S-E-Y-E-D-E-V-S-S-I-T-I-G-N-L-V-M-D-E-L-A-E-L-D-E-I-T-Y-V-R-F-A-S-V-Y-K-S-F-K-D-V-D-E-I-E-E-L-L-Q-Q-I-T-K-R-V-R-S-K-K-S-G-S-V


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-E-K-T-Y-P-M-T-Q-V-E-K-D-Q-L-E-K-E-L-E-E-L-K-L-V-R-R-P-E-V-V-E-R-I-K-I-A-R-S-Y-G-D-L-S-E-N-S-E-Y-D-A-A-K-D-E-Q-A-F-V-E-G-Q-I-Q-I-L-E-T-K-I-R-Y-A-E-I-I-D-S-D-A-V-A-K-D-E-V-A-I-G-K-T-V-L-V-Q-E-V-G-T-N-D-K-D-T-Y-H-I-V-G-A-A-G-A-D-I-F-S-G-K-I-S-N-E-S-P-I-A-H-A-L-I-G-K-K-T-G-D-L-A-T-I-E-S-P-A-G-S-Y-Q-V-E-I-I-S-V-E-K-T-N


### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-S-F-L-I-F-L-V-R-F-Y-Q-K-N-I-S-P-A-F-P-A-S-C-R-Y-R-P-T-C-S-T-Y-M-I-E-A-I-Q-K-H-G-L-K-G-V-L-M-G-I-A-R-I-L-R-C-H-P-L-A-H-G-G-N-D-P-V-P-D-H-F-S-L-R-R-N-K-T-D-I-S-D


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-I-P-V-V-I-E-Q-T-S-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-T-G-Q-V-E-D-N-M-A-N-S-I-I-A-Q-L-L-F-L-D-A-Q-D-N-T-K-D-I-Y-L-Y-V-N-T-P-G-G-S-V-S-A-G-L-A-I-V-D-T-M-N-F-I-K-S-D-V-Q-T-I-V-M-G-M-A-A-S-M-G-T-I-I-A-S-S-G-A-K-G-K-R-F-M-L-P-N-A-E-Y-M-I-H-Q-P-M-G-G-T-G-G-G-T-Q-Q-S-D-M-A-I-A-A-E-H-L-L-K-T-R-H-T-L-E-K-I-L-A-D-N-S-G-Q-S-I-E-K-V-H-D-D-A-E-R-D-R-W-M-S-A-Q-E-T-L-D-Y-G-F-I-D-A-I-M-E-N-N-N-L-Q


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-K-L-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-I-N-I-M-G-F-T-K-E-F-N-A-R-T-A-D-Q-A-G-M-I-I-P-V-V-I-S-V-Y-E-D-K-S-F-D-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-E-K-G-S-G-E-P-N-K-T-K-V-A-T-I-T-R-A-Q-V-Q-E-I-A-E-T-K-M-P-D-L-N-A-A-N-L-E-S-A-M-R-M-I-E-G-T-A-R-S-M-G-F-T-V-T-D


### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-R-A-I-F-A-G-G-C-F-W-C-M-V-Q-P-F-E-E-L-D-G-I-E-S-V-L-S-G-Y-T-G-G-H-V-E-N-P-T-Y-K-E-V-C-S-K-T-T-G-H-T-E-A-V-E-I-I-F-N-P-E-K-I-S-Y-A-D-L-V-E-L-Y-W-A-Q-T-D-P-T-D-A-F-G-Q-F-E-D-R-G-D-N-Y-R-P-V-I-F-Y-E-N-E-E-Q-R-Q-I-A-Q-K-S-K-D-K-L-Q-A-S-G-R-F-D-R-P-I-V-T-S-I-E-P-A-D-T-F-Y-P-A-E-D-Y-H-Q-A-F-Y-R-T-N-P-A-R-Y-A-L-S-S-A-R-R-H-A-F-L-E-E-N-W-H


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-T-Y-A-I-I-K-T-G-G-K-Q-V-K-V-E-V-G-Q-A-I-Y-V-E-K-L-D-V-E-A-G-A-E-V-T-F-N-E-V-V-L-V-G-G-E-T-T-K-V-G-T-P-V-V-E-G-A-T-V-V-G-T-V-E-K-Q-G-K-Q-K-K-V-V-S-Y-K-Y-K-P-K-K-G-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-N-A-I-N-A


### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide  operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-K-R-K-E-I-I-D-D-V-T-M-K-R-A-I-T-R-I-T-Y-E-I-I-E-R-N-K-N-L-D-N-I-V-L-A-G-I-K-T-R-G-V-F-L-A-K-R-I-Q-E-R-L-K-Q-L-E-N-L-D-I-P-V-G-E-L-D-T-K-P-F-R-D-D-M-K-V-E-V-D-T-T-T-M-P-V-D-I-T-D-K-D-I-I-L-I-D-D-V-L-Y-T-G-R-T-I-R-A-A-I-D-N-L-V-S-L-G-R-P-S-R-V-S-L-A-V-L-I-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-Q-F-E-E-I-L-V-E-V-M-E-H-D-G-Y-D-R-V-S-I-I-D-P-S


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-Y-F-N-V-G-K-I-V-N-T-Q-G-L-Q-G-E-M-R-V-L-S-V-T-D-F-V-E-E-R-F-K-K-G-Q-V-L-A-L-F-D-E-K-N-Q-F-V-M-D-I-E-I-A-S-H-R-K-Q-K-N-F-D-I-I-K-F-K-G-M-Y-H-I-N-D-I-E-K-Y-K-G-F-T-L-K-V-A-E-D-Q-L-S-D-L-K-D-G-E-F-Y-Y-H-E-I-I-G-L-D-V-Y-E-G-E-E-L-I-G-K-I-K-E-I-L-Q-P-G-A-N-D-V-W-V-V-E-R-H-G-K-R-D-L-L-L-P-Y-I-P-P-V-V-L-E-V-D-L-S-N-Q-R-V-Q-V-E-L-M-E-G-L-D-D-E-D


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-A-E-E-F-L-N-T-H-N-A-S-I-L-L-S-A-A-N-K-S-H-Y-P-Q-D-D-L-P-E-V-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-L-L-G-R-K-N-L-A-R-T-S-S-K-P-G-K-T-Q-L-L-N-F-Y-N-I-D-D-K-L-R-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-T-E-R-A-K-W-G-K-M-I-E-E-Y-L-V-T-R-D-N-L-R-V-V-V-S-L-V-D-F-R-H-D-P-S-A-D-D-I-Q-M-Y-E-F-L-K-Y-Y-E-I-P-V-I-I-V-A-T-K-A-D-K-I-P-R-G-K-W-N-K-H-E-S-S-I-K-K-K-L-N-F-D-K-K-D-H-F-I-V-F-S-S-V-D-R-T-G-L-D-E-S-W-D-T-I-L-S-E-L


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-E-A-I-I-A-K-K-A-E-Q-V-E-L-I-A-E-K-M-K-A-A-A-S-I-V-V-V-D-S-R-G-L-T-V-E-Q-D-T-N-L-R-R-S-L-R-E-S-D-V-E-F-K-V-I-K-N-S-I-L-T-R-A-A-E-K-A-G-L-E-D-L-K-E-L-F-V-G-P-S-A-V-A-F-S-N-E-D-V-I-A-P-A-K-V-I-S-D-F-A-K-D-A-E-A-L-E-I-K-G-G-S-V-D-G-K-F-T-S-V-E-E-I-N-A-L-A-K-L-P-N-K-E-G-M-L-S-M-L-L-S-V-L-Q-A-P-V-R-N-V-A-Y-A-V-K-A-V-A-E-K-D-E-E-V-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-N-I-E-N-I-I-A-E-I-K-E-A-T-I-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-A-A-A-A-G-G-E-A-A-A-A-K-D-S-F-D-V-E-L-T-A-A-G-D-K-K-V-G-V-I-K-V-V-R-E-I-T-G-E-G-L-K-E-A-K-A-I-V-D-N-A-P-S-V-I-K-E-G-A-S-E-A-E-A-N-E-I-K-E-K-L-E-A-A-G-A-S-V-T-L-K


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-N-N-Y-I-A-S-I-E-N-Y-P-Q-E-G-I-T-F-R-D-I-S-P-L-M-A-D-G-K-A-Y-S-Y-A-V-R-E-I-V-Q-Y-A-A-D-K-D-I-D-M-I-V-G-P-E-A-R-G-F-I-V-G-C-P-V-A-Y-A-L-G-I-G-F-A-P-V-R-K-P-G-K-L-P-R-E-V-I-S-A-D-Y-E-K-E-Y-G-L-D-T-L-T-M-H-A-D-A-I-K-P-G-Q-R-V-L-I-V-D-D-L-L-A-T-G-G-T-V-K-A-T-I-E-M-I-E-K-L-G-G-V-V-A-G-C-A-F-L-V-E-L-D-G-L-N-G-R-K-A-I-E-G-Y-D-T-K-V-L-M-N-F-P-G


### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-I-T-L-F-L-S-P-S-C-T-S-C-R-K-A-R-A-W-L-S-K-H-E-V-A-F-E-E-H-N-I-I-T-S-P-L-N-K-E-E-L-L-Q-I-L-S-F-T-E-N-G-T-E-D-I-I-S-T-R-S-K-V-F-Q-K-L-A-I-D-V-D-E-L-S-T-S-S-L-M-E-L-I-S-E-N-P-S-L-L-R-R-P-I-I-L-D-K-K-R-M-Q-I-G-F-N-E-D-E-I-R-A-F-L-P-R-D-Y-R-K-Q-E-L-K-Q-A-T-I-R-A-E-I-E-G-K-H-D


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-E-V-K-T-L-A-N-I-K-S-A-I-K-R-A-E-L-N-V-K-Q-N-E-K-N-S-A-Q-K-S-A-M-R-T-A-I-K-A-F-E-A-N-P-S-E-E-L-Y-R-A-A-S-S-S-I-D-K-A-A-S-K-G-L-I-H-T-N-K-A-S-R-D-K-A-R-L-A-T-K-L-G


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-Q-L-T-V-Q-V-V-T-P-D-G-I-R-Y-D-H-H-A-S-L-I-T-V-R-T-P-D-G-E-M-G-I-L-P-G-H-I-N-L-I-A-P-L-N-V-H-Q-M-K-I-N-R-S-H-Q-E-G-V-D-W-V-A-V-N-G-G-I-I-E-V-N-E-D-Q-V-T-I-V-A-D-S-A-E-R-A-R-D-I-D-L-N-R-A-E-R-A-K-E-R-A-E-R-A-L-E-K-A-Q-T-T-Q-N-I-D-E-M-R-R-A-E-V-A-L-R-R-A-I-N-R-I-S-V-G-K-K


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-K-K-T-Q-A-L-I-E-Q-Y-S-K-S-L-V-E-V-A-I-E-H-K-I-V-E-K-I-Q-Q-E-V-A-A-L-I-D-I-F-E-T-S-E-L-E-G-V-L-S-S-L-A-V-S-H-D-E-K-Q-H-F-V-K-T-L-Q-T-S-C-S-T-Y-L-V-N-F-L-E-V-I-V-Q-N-E-R-E-A-L-L-Y-P-I-L-K-S-V-D-Q-E-L-I-K-V-N-G-Q-Y-P-I-Q-I-T-T-A-V-A-L-S-P-E-Q-K-E-R-L-F-D-I-A-K-T-K-L-A-L-P-N-G-Q-L-V-E-H-I-D-P-S-I-V-G-G-F-V-V-N-A-N-N-K-V-I-D-A-S-V-R-N-Q-L-H-Q-F-K-M-K-L-K


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-I-L-I-N-S-T-T-I-G-D-I-I-I-V-S-G-S-V-L-L-L-F-I-L-I-K-T-F-A-W-K-Q-I-T-G-I-F-E-A-R-E-Q-K-I-A-N-D-I-D-T-A-E-Q-A-R-Q-Q-A-E-A-F-A-T-K-R-E-E-E-L-S-N-A-K-T-E-A-N-Q-I-I-D-N-A-K-E-T-G-L-A-K-G-D-Q-I-I-S-E-A-K-T-E-A-D-R-L-K-E-K-A-H-Q-D-I-A-Q-N-K-A-E-A-L-A-D-V-K-G-E-V-A-D-L-T-V-L-L-A-E-K-I-M-V-S-N-L-D-K-E-A-Q-S-N-L-I-D-S-Y-I-K-K-L-G-D-A


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-L-Y-P-T-P-I-A-K-L-I-D-S-F-S-K-L-P-G-I-G-T-K-T-A-T-R-L-A-F-Y-T-I-G-M-S-D-E-D-V-N-E-F-A-K-N-L-L-A-A-K-R-E-L-T-Y-C-S-V-C-G-N-L-T-D-D-D-P-C-L-I-C-T-D-K-T-R-D-Q-S-V-I-L-V-V-E-D-S-K-D-V-S-A-M-E-K-I-Q-E-Y-N-G-L-Y-H-V-L-H-G-L-I-S-P-M-N-G-I-S-P-D-D-I-N-L-K-S-L-I-T-R-L-M-D-G-Q-V-T-E-V-I-V-A-T-N-A-T-A-D-G-E-A-T-S-M-Y-I-S-R-V-L-K-P-A-G-I-K-V-T-R-L-A-R-G-L-A-V-G-S-D-I-E-Y-A-D-E-V-T-L-L-R-A-I-E-N-R-T-E-L


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-I-I-E-G-Q-L-V-A-N-E-M-K-I-G-I-V-V-S-R-F-N-E-L-I-T-S-K-L-L-S-G-A-V-D-G-L-L-R-H-G-V-S-E-E-D-I-D-I-V-W-V-P-G-A-F-E-I-P-Y-M-A-R-K-M-A-L-Y-K-D-Y-D-A-I-I-C-L-G-V-V-I-K-G-S-T-D-H-Y-D-Y-V-C-N-E-V-T-K-G-I-G-H-L-N-S-Q-S-D-I-P-H-I-F-G-V-L-T-T-D-N-I-E-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-Y-D-C-A-L-S-A-I-E-M-V-N-L-D-K-K-L-R-E-R


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-I-N-N-I-V-L-V-G-R-M-T-K-D-A-E-L-R-Y-T-P-S-N-Q-A-V-A-T-F-S-L-A-V-N-R-N-F-K-N-Q-S-G-E-R-E-A-D-F-I-N-C-V-I-W-R-Q-Q-A-E-N-L-A-N-W-A-K-K-G-A-L-V-G-I-T-G-R-I-Q-T-R-N-Y-E-N-Q-Q-G-Q-R-I-Y-V-T-E-V-V-A-E-N-F-Q-L-L-E-S-R-N-S-Q-Q-Q-T-N-Q-S-G-N-S-S-N-S-Y-F-G-N-A-N-K-M-D-I-S-D-D-D-L-P-F


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-P-L-I-Q-S-L-T-E-G-Q-L-R-S-D-I-P-E-F-R-A-G-D-T-V-R-V-H-A-K-V-V-E-G-T-R-E-R-I-Q-I-F-E-G-V-V-I-S-R-K-G-Q-G-I-S-E-M-Y-T-V-R-K-I-S-G-G-I-G-V-E-R-T-F-P-I-H-T-P-R-V-D-K-I-E-V-V-R-Y-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-Q-G-K-A-A-R-I-K-E-I-R-R


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-T-Y-R-V-K-S-D-K-D-F-Q-M-I-F-S-R-G-K-N-V-A-N-R-K-F-V-I-Y-Y-L-E-K-E-Q-K-H-F-R-V-G-I-S-V-S-K-K-L-G-N-A-V-V-R-N-A-I-K-R-K-I-R-H-V-L-L-S-Q-K-T-A-L-Q-D-Y-D-F-V-V-I-A-R-K-G-V-E-E-L-D-Y-Q-A-L-E-K-N-L-I-H-V-L-K-I-A-G-L-I


### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-A-S-I-I-Y-S-P-K-D-I-F-E-Q-D-F-K-V-S-M-R-G-Y-D-K-K-E-V-D-V-F-L-D-D-V-I-K-D-Y-E-N-Y-L-E-Q-I-E-K-L-Q-M-E-N-R-R-L-Q-Q-A-L-D-K-K-E-S-E-A-S-N-V-R-N-S-G-T-A-M-Y-N-Q-K-P-I-A-Q-S-A-T-N-F-D-I-L-K-R-I-S-R-L-E-K-E-V-F-G-R-Q-I-R-E


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-N-E-I-I-A-Q-Y-A-R-H-E-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-W-E-I-N-H-L-N-D-H-I-K-Q-H-K-K-D-H-A-T-Y-R-G-L-M-K-K-I-G-H-R-R-N-L-L-A-Y-L-R-R-T-D-V-N-R-Y-R-E-L-I-Q-S-L-G-L-R-R


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-Y-N-K-V-I-M-I-G-R-L-T-A-K-P-E-M-V-K-T-P-T-D-K-S-V-T-R-A-T-V-A-V-N-R-R-F-K-G-S-N-G-E-R-E-A-D-F-I-N-V-V-M-W-G-R-L-A-E-T-L-A-S-Y-G-T-K-G-S-L-I-S-I-D-G-E-L-R-T-R-K-Y-E-K-D-G-Q-T-H-Y-I-T-E-V-L-A-S-S-F-Q-L-L-E-S-R-A-Q-R-A-M-R-E-N-N-V-S-G-D-L-S-D-L-V-L-E-E-E-E-L-P-F


### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-E-L-E-V-F-A-G-Q-E-K-S-E-L-S-M-I-E-V-A-R-A-I-L-E-Q-R-G-R-D-N-E-M-Y-F-S-D-L-V-N-D-I-Q-T-Y-L-G-K-S-D-S-A-I-R-E-S-L-P-F-F-Y-S-D-L-N-T-D-G-S-F-I-P-L-G-E-N-K-W-G-L-R-S-W-Y-A-I-D-E-I-D-E-E-I-I-T-L-E-E-D-E-D-G-A-P-K-R-K-K-K-R-V-N-A-F-M-D-G-D-E-D-A-I-D-Y-N-D-D-D-P-E-D-E-D-F-T-E-E-T-P-S-L-E-Y-D-E-E-N-P-D-D-E-K-S-E-V-E-S-Y-D-S-E-I-N-E-I-I-P-D-E-D-L-D-E-D-V-E-I-N-E-E-D-D-E-E-E-E-E-E-E-E-V


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-V-F-N-K-L-F-K-R-R-H-S-V-S-E-E-I-K-K-D-D-L-Q-E-E-V-E-A-T-E-T-E-E-T-V-E-E-V-I-E-E-I-P-E-K-S-E-L-E-L-A-N-E-R-A-D-E-F-E-N-K-Y-L-R-A-H-A-E-M-Q-N-I-Q-R-R-S-S-E-E-R-Q-Q-L-Q-R-Y-R-S-Q-D-L-A-K-A-I-L-P-S-L-D-N-L-E-R-A-L-A-V-E-G-L-T-D-D-V-K-K-G-L-E-M-T-R-D-S-L-I-Q-A-L-K-E-E-G-V-E-E-V-E-V-D-S-F-D-H-N-F-H-M-A-V-Q-T-L-P-A-D-D-E-H-P-A-D-S-I-A-E-V-F-Q-K-G-Y-K-L-H-E-R-L-L-R-P-A-M-V-V-V-Y-N


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-E-G-S-R-K-V-R-N-R-V-G-R-G-T-S-S-G-N-G-K-T-S-G-R-G-Q-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-M-P-K-R-G-F-S-N-I-N-A-K-E-Y-A-L-V-N-L-D-Q-L-N-V-F-E-D-G-T-E-V-T-P-V-V-L-K-E-A-G-I-V-R-A-E-K-S-G-V-K-I-L-G-N-G-E-L-T-K-K-L-S-V-K-A-A-K-F-S-K-S-A-E-A-A-I-T-A-K-G-G-S-I-E-V-I


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-F-K-D-N-A-V-E-L-E-E-R-V-V-A-I-N-R-V-T-K-V-V-K-G-G-R-R-L-R-F-A-A-L-V-V-V-G-D-R-N-G-R-V-G-F-G-T-G-K-A-Q-E-V-P-E-A-I-R-K-A-V-E-A-A-K-K-N-M-V-E-V-P-M-V-G-T-T-I-P-H-E-V-R-S-E-F-G-G-A-K-V-L-L-K-P-A-V-E-G-A-G-V-A-A-G-G-A-V-R-A-V-I-E-L-A-G-V-A-D-I-T-S-K-S-L-G-S-N-T-P-I-N-I-V-R-A-T-V-E-G-L-K-Q-L-K-R-A-E-E-V-A-A-L-R-G-I-S-V-S-D-L-A


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-I-R-Q-K-R-H-R-R-V-R-G-K-L-S-G-T-A-D-R-P-R-L-N-I-F-R-S-N-T-G-I-Y-A-Q-V-I-D-D-V-A-G-V-T-L-A-S-A-S-T-L-D-K-E-V-S-N-G-T-K-T-E-Q-A-V-V-V-G-K-L-V-A-E-R-A-V-A-K-G-I-S-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-D-S-A-R-E-N-G-L-K-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-V-I-T-L-P-A-G-V-E-I-I-N-K-D-N-V-V-T-V-K-G-P-K-G-Q-L-T-R-E-F-N-K-N-I-G-I-T-V-E-G-T-E-V-T-V-T-R-P-N-D-S-K-E-M-K-T-I-H-G-T-T-R-A-N-L-N-N-M-V-V-G-V-S-E-G-F-K-K-A-L-E-M-R-G-V-G-Y-R-A-Q-L-Q-G-S-K-L-V-L-S-V-G-K-S-H-Q-D-E-V-E-A-P-E-G-V-T-F-E-V-P-T-P-T-T-I-N-V-I-G-I-N-K-E-S-V-G-Q-T-A-A-Y-V-R-S-L-R-S-P-E-P-Y-K-G-K-G-I-R-Y-V-G-E-F-V-R-R-K-E-G-K-T-G-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-F-L-T-R-I-R-N-A-N-Q-A-K-H-E-V-L-E-V-P-A-S-N-I-K-K-G-I-A-D-I-L-K-R-E-G-F-V-K-N-V-E-V-I-E-D-D-K-Q-G-I-I-R-V-F-L-K-Y-G-Q-N-G-E-R-V-I-T-N-L-K-R-I-S-K-P-G-L-R-V-Y-T-K-H-E-D-M-P-K-V-L-N-G-L-G-I-A-I-V-S-T-S-E-G-L-L-T-D-K-E-A-R-Q-K-N-I-G-G-E-V-L-A-Y-I-W


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-N-K-R-P-A-K-F-S-T-Q-A-Y-T-R-C-E-K-C-G-R-P-H-S-V-Y-R-K-F-Q-L-C-R-V-C-F-R-D-L-A-Y-K-G-Q-V-P-G-V-T-K-A-S-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-N-R-L-K-E-K-Y-T-N-E-V-V-P-A-L-T-E-K-F-N-Y-S-S-V-M-A-V-P-K-V-E-K-I-V-L-N-M-G-V-G-D-A-V-S-N-A-K-N-L-E-K-A-A-A-E-L-A-L-I-S-G-Q-K-P-L-I-T-K-A-K-K-S-I-A-G-F-R-L-R-E-G-V-A-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-V-S-V-S-L-P-R-V-R-D-F-H-G-V-P-T-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-N-F-D-D-V-D-K-V-R-G-L-D-I-V-I-V-T-T-A-N-T-D-E-E-S-R-E-L-L-K-G-L-G-M-P-F-A-K


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-F-V-K-K-G-D-K-V-R-V-I-A-G-K-D-K-G-T-E-A-V-V-L-K-A-L-P-K-V-N-K-V-V-V-E-G-V-A-L-I-K-K-H-Q-K-P-N-N-E-N-P-Q-G-A-I-V-E-K-E-A-P-I-H-V-S-N-V-Q-V-L-D-K-N-G-V-A-G-R-V-G-Y-K-V-V-D-G-K-K-V-R-Y-N-K-K-S-G-E-V-L-D


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-K-V-A-D-N-S-G-A-R-E-I-L-T-I-K-V-L-G-G-S-G-R-K-F-A-N-I-G-D-V-I-V-A-S-V-K-Q-A-T-P-G-G-A-V-K-K-G-D-V-V-K-A-V-I-V-R-T-K-T-G-A-R-R-P-D-G-S-Y-I-K-F-D-D-N-A-A-V-I-I-R-D-D-K-T-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-G-Y-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-N-Q-R-K-T-L-Y-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-K-R-N-H-P-V-Y-G-K-R-I-N-Y-S-K-K-Y-K-A-H-D-E-N-N-V-A-K-E-G-D-I-V-R-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-V-V-E-K-A-V-I-I


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-H-R-R-E-F-R-G-K-M-R-G-E-A-K-G-G-K-E-V-S-F-G-E-Y-G-L-Q-A-T-T-S-H-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-A-K-A-I-G-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-P-V-K-R-G-K-V-M-F-E-I-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-C-K-F-V-K-R-E-A-E


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-E-I-T-S-A-K-A-M-A-R-T-V-R-V-S-P-R-K-T-R-L-V-L-D-L-I-R-G-K-N-V-A-D-A-I-A-I-L-K-F-T-P-N-K-A-A-R-V-I-E-K-T-L-N-S-A-I-A-N-A-E-N-N-F-G-L-E-K-A-N-L-V-V-S-E-T-F-A-N-E-G-P-T-M-K-R-F-R-P-R-A-K-G-S-A-S-P-I-N-K-R-T-T-H-V-T-V-V-V-S-E-K


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-K-M-I-V-G-L-G-N-P-G-S-K-Y-N-D-T-K-H-N-I-G-F-M-A-V-D-R-I-V-K-D-L-D-V-N-F-T-E-D-K-N-F-K-A-E-I-G-S-D-F-I-N-G-E-K-I-Y-F-I-K-P-T-T-F-M-N-N-S-G-I-A-V-K-A-L-L-T-Y-Y-N-I-S-I-K-D-M-I-I-I-Y-D-D-L-D-M-E-V-G-K-I-R-F-R-Q-K-G-S-A-G-G-H-N-G-I-K-S-I-I-A-H-L-G-T-Q-E-F-D-R-I-K-V-G-I-G-R-P-N-G-R-M-T-V-I-N-H-V-L-G-K-F-D-K-N-D-E-I-M-I-L-N-T-L-D-K-V-D-N-A-V-N-Y-Y-L-Q-T-N-D-F-Q-K-T-M-Q-K-Y-N-G-L-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-F-L-Q-D-V-K-G-K-G-K-K-G-E-V-K-E-V-P-T-G-Y-A-Q-N-F-L-L-K-K-N-L-A-K-E-A-T-T-Q-A-I-G-E-L-K-G-K-Q-K-S-E-E-K-A-Q-A-E-I-L-A-Q-A-K-E-L-K-T-Q-L-E-S-E-T-T-R-V-Q-F-I-E-K-V-G-P-D-G-R-T-F-G-S-I-T-A-K-K-I-A-E-E-L-Q-K-Q-Y-G-I-K-I-D-K-R-H-I-D-L-D-H-T-I-R-A-I-G-K-V-E-V-P-V-K-L-H-K-Q-V-S-S-Q-I-K-L-D-I-K-E-A


### FUNCTION The RuvA-RuvB-RuvC complex processes Holliday junction  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA ### SEQUENCE -M-Y-D-Y-I-K-G-K-L-S-K-I-T-A-K-F-I-V-V-E-T-A-G-L-G-Y-M-I-Y-V-A-N-P-Y-S-F-S-G-Y-V-N-Q-E-V-T-I-Y-L-H-Q-V-I-R-D-D-A-H-L-L-F-G-F-H-T-E-N-E-K-E-I-F-L-N-L-I-S-V-S-G-I-G-P-T-T-A-L-A-I-I-A-V-D-D-N-E-G-L-V-S-A-I-D-N-S-D-I-K-Y-L-T-K-F-P-K-I-G-K-K-T-A-Q-Q-M-I-L-D-L-S-G-K-F-V-E-A-S-G-E-S-A-T-S-R-K-V-S-S-E-Q-N-S-N-L-E-E-A-M-E-A-L-L-A-L-G-Y-K-A-T-E-L-K-K-V-K-A-F-F-E-G-T-N-E-T-V-E-Q-Y-I-K-S-S-L-K-M-L-M-K


### FUNCTION With S4 and S5 plays an important role in translational accuracy ### SEQUENCE -M-P-T-I-N-Q-L-V-R-K-P-R-K-S-K-V-E-K-S-D-S-P-A-L-N-I-G-Y-N-S-H-R-K-V-H-T-K-L-S-A-P-Q-K-R-G-V-A-T-R-V-G-T-M-T-P-K-K-P-N-S-A-L-R-K-F-A-R-V-R-L-S-N-L-I-E-V-T-A-Y-I-P-G-I-G-H-N-L-Q-E-H-S-V-V-L-I-R-G-G-R-V-K-D-L-P-G-V-R-Y-H-I-V-R-G-A-L-D-T-A-G-V-A-D-R-K-Q-G-R-S-K-Y-G-A-K-R-P-K-G


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA ### SEQUENCE -M-S-R-K-N-Q-A-P-K-R-E-V-L-P-D-P-L-Y-N-S-K-I-V-T-R-L-I-N-R-V-M-L-D-G-K-R-G-T-A-A-T-I-V-Y-D-A-F-E-A-I-K-E-A-T-G-T-D-A-L-E-V-F-E-T-A-M-E-N-I-M-P-V-L-E-V-R-A-R-R-V-G-G-S-N-Y-Q-V-P-V-E-V-R-P-E-R-R-T-T-L-G-L-R-W-L-V-N-A-S-R-A-R-G-E-H-T-M-K-D-R-L-A-K-E-I-M-D-A-A-N-N-T-G-A-S-V-K-K-R-E-D-T-H-K-M-A-E-A-N-R-A-F-A-H-F-R-W


### FUNCTION A non-essential component of RNA polymerase ### SEQUENCE -M-I-Y-K-V-F-Y-Q-E-T-K-E-R-N-P-R-R-E-Q-T-K-T-L-Y-V-T-I-D-A-A-N-E-L-E-G-R-I-A-A-R-K-L-V-E-E-N-T-A-Y-N-I-E-F-I-E-L-L-S-D-K-H-L-E-Y-E-K-E-T-G-V-F-E-L-T-E-F


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-F-Q-K-Q-Q-K-L-V-E-Q-Y-A-E-L-R-R-E-L-K-E-K-G-D-Y-E-A-L-R-K-L-P-K-D-S-N-P-N-R-L-K-N-R-D-L-I-D-G-R-P-H-A-Y-M-R-K-F-G-M-S-R-I-N-F-R-N-L-A-Y-K-G-Q-I-P-G-I-K-K-A-S-W


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Q-Q-R-R-G-G-F-K-R-R-K-K-V-D-Y-I-A-A-N-K-I-E-Y-V-D-Y-K-D-T-E-L-L-S-R-F-V-S-E-R-G-K-I-L-P-R-R-V-T-G-T-S-A-K-N-Q-R-K-V-T-T-A-I-K-R-A-R-V-M-A-L-M-P-Y-V-N-E-D


### FUNCTION Allows the formation of correctly charged Asn-tRNA ### SEQUENCE -M-K-I-S-E-E-E-V-R-H-V-A-N-L-S-K-L-R-F-S-D-Q-E-T-K-E-F-A-S-S-L-S-K-I-V-D-M-I-E-L-L-N-E-V-D-T-E-G-V-P-V-T-T-T-M-A-D-R-K-T-V-M-R-E-D-I-A-Q-P-G-N-N-R-D-D-L-F-K-N-V-P-Q-H-Q-D-Y-Y-I-K-V-P-A-I-L-E-D-G-G-D-A


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-R-C-P-K-C-G-Y-N-K-S-S-V-V-D-S-R-Q-A-E-E-G-T-T-I-R-R-R-R-E-C-E-K-C-G-N-R-F-T-T-F-E-R-L-E-E-L-P-L-L-V-I-K-K-D-G-T-R-E-Q-F-S-R-D-K-I-L-N-G-I-I-Q-S-A-Q-K-R-P-V-S-S-E-D-I-E-N-C-I-L-R-I-E-R-K-I-R-S-E-Y-E-D-E-V-S-S-I-T-I-G-N-L-V-M-D-E-L-A-E-L-D-E-I-T-Y-V-R-F-A-S-V-Y-K-S-F-K-D-V-D-E-I-E-E-L-L-Q-Q-I-T-K-R-V-R-S-K-K-S-G-S-V


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-A-E-K-T-Y-P-M-T-Q-V-E-K-D-Q-L-E-K-E-L-E-E-L-K-L-V-R-R-P-E-V-V-E-R-I-K-I-A-R-S-Y-G-D-L-S-E-N-S-E-Y-D-A-A-K-D-E-Q-A-F-V-E-G-Q-I-Q-I-L-E-T-K-I-R-Y-A-E-I-I-D-S-D-A-V-A-K-D-E-V-A-I-G-K-T-V-L-V-Q-E-V-G-T-N-D-K-D-T-Y-H-I-V-G-A-A-G-A-D-I-F-S-G-K-I-S-N-E-S-P-I-A-H-A-L-I-G-K-K-T-G-D-L-A-T-I-E-S-P-A-G-S-Y-Q-V-E-I-I-S-V-E-K-T-N


### FUNCTION Could be involved in insertion of integral membrane proteins into the membrane ### SEQUENCE -M-L-K-S-F-L-I-F-L-V-R-F-Y-Q-K-N-I-S-P-A-F-P-A-S-C-R-Y-C-P-T-C-S-T-Y-M-I-E-A-I-Q-K-H-G-L-K-G-V-L-M-G-I-A-R-I-L-R-C-H-P-L-A-H-G-G-N-D-P-V-P-D-H-F-S-L-R-R-N-K-T-D-I-S-D


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-I-P-V-V-I-E-Q-T-S-R-G-E-R-S-Y-D-I-Y-S-R-L-L-K-D-R-I-I-M-L-T-G-Q-V-E-D-N-M-A-N-S-I-I-A-Q-L-L-F-L-D-A-Q-D-N-T-K-D-I-Y-L-Y-V-N-T-P-G-G-S-V-S-A-G-L-A-I-V-D-T-M-N-F-I-K-S-D-V-Q-T-I-V-M-G-M-A-A-S-M-G-T-I-I-A-S-S-G-A-K-G-K-R-F-M-L-P-N-A-E-Y-M-I-H-Q-P-M-G-G-T-G-G-G-T-Q-Q-S-D-M-A-I-A-A-E-H-L-L-K-T-R-H-T-L-E-K-I-L-A-D-N-S-G-Q-S-I-E-K-V-H-D-D-A-E-R-D-R-W-M-S-A-Q-E-T-L-D-Y-G-F-I-D-A-I-M-E-N-N-N-L-Q


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-A-K-K-V-E-K-L-V-K-L-Q-I-P-A-G-K-A-T-P-A-P-P-V-G-P-A-L-G-Q-A-G-I-N-I-M-G-F-T-K-E-F-N-A-R-T-A-D-Q-A-G-M-I-I-P-V-V-I-S-V-Y-E-D-K-S-F-D-F-I-T-K-T-P-P-A-A-V-L-L-K-K-A-A-G-V-E-K-G-S-G-E-P-N-K-T-K-V-A-T-V-T-R-A-Q-V-Q-E-I-A-E-T-K-M-P-D-L-N-A-A-N-L-E-S-A-M-R-M-I-E-G-T-A-R-S-M-G-F-T-V-T-D


### FUNCTION Has an important function as a repair enzyme for proteins that have been inactivated by oxidation Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine ### SEQUENCE -M-E-R-A-I-F-A-G-G-C-F-W-C-M-V-Q-P-F-E-E-L-D-G-I-E-S-V-L-S-G-Y-T-G-G-H-V-E-N-P-T-Y-K-E-V-C-S-K-T-T-G-H-T-E-A-V-E-I-I-F-N-P-E-K-I-S-Y-A-N-L-V-E-L-Y-W-A-Q-T-D-P-T-D-A-F-G-Q-F-E-D-R-G-D-N-Y-R-P-V-I-F-Y-E-N-E-E-Q-R-Q-I-A-Q-K-S-K-D-K-L-Q-A-S-G-R-F-D-R-P-I-V-T-S-I-E-P-A-D-T-F-Y-P-A-E-D-Y-H-Q-A-F-Y-R-T-N-P-A-R-Y-A-L-S-S-A-R-R-H-A-F-L-E-E-N-W-H


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-S-T-Y-A-I-I-K-T-G-G-K-Q-V-K-V-E-V-G-Q-A-I-Y-V-E-K-L-D-V-E-A-G-A-E-V-T-F-N-E-V-V-L-V-G-G-E-T-T-K-V-G-T-P-V-V-E-G-A-T-V-V-G-T-V-E-K-Q-G-K-Q-K-K-V-V-S-Y-K-Y-K-P-K-K-G-S-H-R-K-Q-G-H-R-Q-P-Y-T-K-V-V-I-N-A-I-N-A


### FUNCTION Regulates transcriptional attenuation of the pyrimidine nucleotide  operon by binding in a uridine-dependent manner to specific sites on pyr mRNA This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes ### SEQUENCE -M-K-R-K-E-I-I-D-D-V-T-M-K-R-A-I-T-R-I-T-Y-E-I-I-E-R-N-K-N-L-D-N-I-V-L-A-G-I-K-T-R-G-V-F-L-A-K-R-I-Q-E-R-L-K-Q-L-E-N-L-D-I-P-V-G-E-L-D-T-K-P-F-R-D-D-M-K-V-E-V-D-T-T-T-M-P-V-D-I-T-D-K-D-I-I-L-I-D-D-V-L-Y-T-G-R-T-I-R-A-A-I-D-N-L-V-S-L-G-R-P-S-R-V-S-L-A-V-L-I-D-R-G-H-R-E-L-P-I-R-A-D-Y-V-G-K-N-I-P-T-S-Q-F-E-E-I-L-V-E-V-M-E-H-D-G-Y-D-R-V-S-I-I-D-P-S


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-E-Y-F-N-V-G-K-I-V-N-T-Q-G-L-Q-G-E-M-R-V-L-S-V-T-D-F-V-E-E-R-F-K-K-G-Q-V-L-A-L-F-D-E-K-N-Q-F-V-M-D-I-E-I-A-S-H-R-K-Q-K-N-F-D-I-I-K-F-K-G-M-Y-H-I-N-D-I-E-K-Y-K-G-F-T-L-K-V-A-E-D-Q-L-S-D-L-K-D-G-E-F-Y-Y-H-E-I-I-G-L-D-V-Y-E-G-E-E-L-I-G-K-I-K-E-I-L-Q-P-G-A-N-D-V-W-V-V-E-R-H-G-K-R-D-L-L-L-P-Y-I-P-P-V-V-L-E-V-D-L-S-N-Q-R-V-Q-V-E-L-M-E-G-L-D-D-E-D


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-A-E-E-F-L-N-T-H-N-A-S-I-L-L-S-A-A-N-K-S-H-Y-P-Q-D-D-L-P-E-V-A-L-A-G-R-S-N-V-G-K-S-S-F-I-N-T-L-L-G-R-K-N-L-A-R-T-S-S-K-P-G-K-T-Q-L-L-N-F-Y-N-I-D-D-K-L-R-F-V-D-V-P-G-Y-G-Y-A-K-V-S-K-T-E-R-A-K-W-G-K-M-I-E-E-Y-L-V-T-R-D-N-L-R-V-V-V-S-L-V-D-F-R-H-D-P-S-A-D-D-I-Q-I-Y-E-F-L-K-Y-Y-E-I-P-V-I-I-V-A-T-K-A-D-K-I-P-R-G-K-W-N-K-H-E-S-S-I-K-K-K-L-N-F-D-K-K-D-H-F-I-V-F-S-S-V-D-R-T-G-L-D-E-S-W-D-T-I-L-S-E-L


### FUNCTION Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors ### SEQUENCE -M-S-E-A-I-I-A-K-K-A-E-Q-V-E-L-I-A-E-K-M-K-A-A-A-S-I-V-V-V-D-S-R-G-L-T-V-E-Q-D-T-N-L-R-R-S-L-R-E-S-D-V-E-F-K-V-I-K-N-S-I-L-I-R-A-A-E-K-A-G-L-E-D-L-K-E-L-F-V-G-P-S-A-V-A-F-S-N-E-D-V-I-A-P-A-K-V-I-S-D-F-A-K-D-A-E-A-L-E-I-K-G-G-S-V-D-G-K-F-T-S-V-E-E-I-N-A-L-A-K-L-P-N-K-E-G-M-L-S-M-L-L-S-V-L-Q-A-P-V-R-N-V-A-Y-A-V-K-A-V-A-E-K-D-E-E-V-A


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors Is thus essential for accurate translation ### SEQUENCE -M-A-L-N-I-E-N-I-I-A-E-I-K-E-A-T-I-L-E-L-N-D-L-V-K-A-I-E-E-E-F-G-V-T-A-A-A-P-V-A-A-A-A-A-S-G-E-A-A-A-A-K-D-S-F-D-V-E-L-T-A-A-G-D-K-K-V-G-V-I-K-V-V-R-E-I-T-G-E-G-L-K-E-A-K-A-I-V-D-N-A-P-S-V-I-K-E-G-A-S-E-A-E-A-N-E-I-K-E-K-L-E-A-A-G-A-S-V-T-L-K


### FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis ### SEQUENCE -M-D-L-N-N-Y-I-A-S-I-E-N-Y-P-Q-E-G-I-T-F-R-D-I-S-P-L-M-A-D-G-K-A-Y-S-Y-A-V-R-E-I-V-Q-Y-A-A-D-K-D-I-D-M-I-V-G-P-E-A-R-G-F-I-V-G-C-P-V-A-Y-A-L-G-I-G-F-A-P-V-R-K-P-G-K-L-P-R-E-V-I-S-A-D-Y-E-K-E-Y-G-L-D-T-L-T-M-H-A-D-A-I-K-P-G-Q-R-V-L-I-V-D-D-L-L-A-T-G-G-T-V-K-A-T-I-E-M-I-E-K-L-G-G-V-V-A-G-C-A-F-L-V-E-L-D-G-L-N-G-R-K-A-I-E-G-Y-D-T-K-V-L-M-N-F-P-G


### FUNCTION Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator ### SEQUENCE -M-I-T-L-F-L-S-P-S-C-T-S-C-R-K-A-R-A-W-L-S-K-H-E-V-A-F-E-E-H-N-I-I-T-S-P-L-N-K-E-E-L-L-Q-I-L-S-F-T-E-N-G-T-E-D-I-I-S-T-R-S-K-V-F-Q-K-L-A-I-D-V-D-E-L-S-T-S-S-L-M-E-L-I-S-E-N-P-S-L-L-R-R-P-I-I-L-D-K-K-R-M-Q-I-G-F-N-E-D-E-I-R-A-F-L-P-R-D-Y-R-K-Q-E-L-K-Q-A-T-I-R-A-E-I-E-G-K-H-D


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-I-K-S-A-I-K-R-A-E-L-N-V-K-Q-N-E-K-N-S-A-Q-K-S-A-M-R-T-A-I-K-A-F-E-A-N-P-S-E-E-L-Y-R-A-A-S-S-S-I-D-K-A-A-S-K-G-L-I-H-T-N-K-A-S-R-D-K-A-R-L-A-T-K-L-G


### FUNCTION Produces ATP from ADP in the presence of a proton gradient across the membrane ### SEQUENCE -M-A-Q-L-T-V-Q-V-V-T-P-D-G-I-R-Y-D-H-H-A-S-L-I-T-V-R-T-P-D-G-E-M-G-I-L-P-G-H-I-N-L-I-A-P-L-I-V-H-Q-M-K-I-N-R-S-H-Q-E-G-V-D-W-V-A-V-N-G-G-I-I-E-V-N-E-D-Q-V-T-I-V-A-D-S-A-E-R-A-R-D-I-D-L-N-R-A-E-R-A-K-E-R-A-E-R-A-L-E-K-A-Q-T-T-Q-N-I-D-E-M-R-R-A-E-V-A-L-R-R-A-I-N-R-I-S-V-G-K-K


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-K-K-T-Q-A-L-I-E-Q-Y-S-K-S-L-V-E-V-A-I-E-H-K-I-V-E-K-I-Q-Q-E-V-A-A-L-I-D-I-F-E-T-S-E-L-E-G-V-L-S-S-L-A-V-S-H-D-E-K-Q-H-F-V-K-T-L-Q-T-S-C-S-T-Y-L-V-N-F-L-E-V-I-V-Q-N-E-R-E-A-L-L-Y-P-I-L-K-S-V-D-Q-E-L-I-K-V-N-G-Q-Y-P-I-Q-I-T-T-A-V-A-L-S-P-E-Q-K-E-R-L-F-D-I-A-K-T-K-L-A-L-P-N-G-Q-L-V-E-H-I-D-P-S-I-V-G-G-F-V-V-N-A-N-N-K-V-I-D-A-S-V-R-N-Q-L-H-Q-F-K-M-K-L-K


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-S-I-L-I-N-S-T-T-I-G-D-I-I-I-V-S-G-S-V-L-L-L-F-I-L-I-K-T-F-A-W-K-Q-I-T-G-I-F-E-A-R-E-Q-K-I-A-N-D-I-D-T-A-E-Q-A-R-Q-Q-A-E-A-F-A-T-K-R-E-E-E-L-S-N-A-K-T-E-A-N-Q-I-I-D-N-A-K-E-T-G-L-A-K-G-D-Q-I-I-S-E-A-K-T-E-A-D-R-L-K-E-K-A-H-Q-D-I-A-Q-N-K-A-E-A-L-A-D-V-K-G-E-V-A-D-L-T-V-L-L-A-E-K-I-M-V-S-N-L-D-K-E-A-Q-S-N-L-I-D-S-Y-I-K-K-L-G-D-A


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-L-Y-P-T-P-I-A-K-L-I-D-S-F-S-K-L-P-G-I-G-T-K-T-A-T-R-L-A-F-Y-T-I-G-M-S-D-E-D-V-N-E-F-A-K-N-L-L-A-A-K-R-E-L-T-Y-C-S-V-C-G-N-L-T-D-D-D-P-C-L-I-C-T-D-K-T-R-D-Q-S-V-I-L-V-V-E-D-S-K-D-V-S-A-M-E-K-I-Q-E-Y-N-G-L-Y-H-V-L-H-G-L-I-S-P-M-N-G-I-S-P-D-D-I-N-L-K-S-L-I-T-R-L-M-D-G-Q-V-T-E-V-I-V-A-T-N-A-T-A-D-G-E-A-T-S-M-Y-I-S-R-V-L-K-P-A-G-I-K-V-T-R-L-A-R-G-L-A-V-G-S-D-I-E-Y-A-D-E-V-T-L-L-R-A-I-E-N-R-T-E-L


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-T-I-I-E-G-Q-L-V-A-N-E-M-K-I-G-I-V-V-S-R-F-N-E-L-I-T-S-K-L-L-S-G-A-V-D-G-L-L-R-H-G-V-S-E-E-D-I-D-I-V-W-V-P-G-A-F-E-I-P-Y-M-A-R-K-M-A-L-Y-K-D-Y-D-A-I-I-C-L-G-V-V-I-K-G-S-T-D-H-Y-D-Y-V-C-N-E-V-T-K-G-I-G-H-L-N-S-Q-S-D-I-P-H-I-F-G-V-L-T-T-D-N-I-E-Q-A-I-E-R-A-G-T-K-A-G-N-K-G-Y-D-C-A-L-S-A-I-E-M-V-N-L-D-K-K-L-R-E-R


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-P-L-I-Q-S-L-T-E-G-Q-L-R-S-D-I-P-E-F-R-A-G-D-T-V-R-V-H-A-K-V-V-E-G-T-R-E-R-I-Q-I-F-E-G-V-V-I-S-R-K-G-Q-G-I-S-E-M-Y-T-V-R-K-I-S-G-G-I-G-V-E-R-T-F-P-I-H-T-P-R-V-D-K-I-E-V-V-R-Y-G-K-V-R-R-A-K-L-Y-Y-L-R-A-L-Q-G-K-A-A-R-I-K-E-I-R-R


### FUNCTION RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus It can also cleave other RNA substrates such as 45S RNA The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme ### SEQUENCE -M-K-K-T-Y-R-V-K-S-D-K-D-F-Q-M-I-F-S-R-G-K-N-V-A-N-R-K-F-V-I-Y-Y-L-E-K-E-Q-K-H-F-R-V-G-I-S-V-S-K-K-L-G-N-A-V-V-R-N-A-I-K-R-K-I-R-H-V-L-L-S-Q-K-T-A-L-Q-D-Y-D-F-V-V-I-A-R-K-G-V-E-E-L-N-Y-Q-A-L-E-K-N-L-I-H-V-L-K-I-A-G-L-I


### FUNCTION Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed Also contributes to the recruitment of PBP1 to the division complex Not essential for septum formation ### SEQUENCE -M-A-S-I-I-Y-S-P-K-D-I-F-E-Q-D-F-K-V-S-M-R-G-Y-D-K-K-E-V-D-V-F-L-D-D-V-I-K-D-Y-E-N-Y-L-E-Q-I-E-K-L-Q-M-E-N-R-R-L-Q-Q-A-L-D-K-K-E-S-E-A-S-N-V-R-N-S-G-T-A-M-Y-N-Q-K-P-I-A-Q-S-A-T-N-F-D-I-L-K-R-I-S-R-L-E-K-E-V-F-G-R-Q-I-R-E


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-A-I-S-K-E-K-K-N-E-I-I-A-Q-Y-A-R-H-E-G-D-T-G-S-V-E-V-Q-V-A-V-L-T-W-E-I-N-H-L-N-D-H-I-K-Q-H-K-K-D-H-A-T-Y-R-G-L-M-K-K-I-G-H-R-R-N-L-L-A-Y-L-R-R-T-D-V-N-R-Y-R-E-L-I-Q-S-L-G-L-R-R


### FUNCTION Plays an important role in DNA replication, recombination and repair Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ### SEQUENCE -M-Y-N-K-V-I-M-I-G-R-L-T-A-K-P-E-M-V-K-T-P-T-D-K-S-V-T-R-A-T-V-A-V-N-R-R-F-K-G-S-N-G-E-R-E-A-D-F-I-N-V-V-M-W-G-R-L-A-E-T-L-A-S-Y-G-T-K-G-S-L-I-S-V-D-G-E-L-R-T-R-K-Y-E-K-D-G-Q-T-H-Y-I-T-E-V-L-A-S-S-F-Q-L-L-E-S-R-S-Q-R-A-M-R-E-N-N-I-S-G-D-L-S-D-L-V-L-E-E-E-E-L-P-F


### FUNCTION Participates in both the initiation and recycling phases of transcription In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling ### SEQUENCE -M-E-L-E-V-F-A-G-Q-E-K-S-E-L-S-M-I-E-V-A-R-A-I-L-E-Q-R-G-R-D-N-E-M-Y-F-S-D-L-V-N-D-I-Q-T-Y-L-G-K-S-D-S-A-I-R-E-S-L-P-F-F-Y-S-D-L-N-T-D-G-S-F-I-P-L-G-E-N-K-W-G-L-R-S-W-Y-A-I-D-E-I-D-E-E-I-I-T-L-E-E-D-E-D-G-A-P-K-R-K-K-K-R-V-N-A-F-M-D-G-D-E-D-A-I-D-Y-N-D-D-D-P-E-D-E-D-F-T-E-E-T-P-S-L-E-Y-D-E-E-N-P-D-D-E-K-S-E-V-E-S-Y-D-S-E-I-N-E-I-I-P-D-E-D-L-D-E-D-V-E-I-N-E-E-D-D-E-E-E-E-E-E-E-E-V


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-A-V-F-N-K-L-F-K-R-R-H-S-V-S-E-E-I-K-K-D-D-L-Q-E-E-V-E-A-T-E-T-E-E-T-V-E-E-V-I-E-E-I-P-E-K-S-E-L-E-L-A-N-E-R-A-D-E-F-E-N-K-Y-L-R-A-H-A-E-M-Q-N-I-Q-R-R-S-S-E-E-R-Q-Q-L-Q-R-Y-R-S-Q-D-L-A-K-A-I-L-P-S-L-D-N-L-E-R-A-L-A-V-E-G-L-T-D-D-V-K-K-G-L-E-M-T-R-D-S-L-I-Q-A-L-K-E-E-G-V-E-E-V-E-V-D-S-F-D-H-N-F-H-M-A-V-Q-T-L-P-A-D-D-E-H-P-A-D-S-I-A-E-V-F-Q-K-G-Y-K-L-H-E-R-L-L-R-P-A-M-V-V-V-Y-N


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-L-H-E-L-K-P-A-E-G-S-R-K-V-R-N-R-V-G-R-G-T-S-S-G-N-G-K-T-S-G-R-G-Q-K-G-Q-K-A-R-S-G-G-G-V-R-L-G-F-E-G-G-Q-T-P-L-F-R-R-M-P-K-R-G-F-S-N-I-N-A-K-E-Y-A-L-V-N-L-D-Q-L-N-V-F-E-D-G-T-E-V-T-P-V-V-L-K-E-A-G-I-V-R-A-E-K-S-G-V-K-I-L-G-N-G-E-L-T-K-K-L-S-V-K-A-A-K-F-S-K-S-A-E-A-A-I-T-A-K-G-G-S-I-E-V-I


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-F-K-D-N-A-V-E-L-E-E-R-V-V-A-I-N-R-V-T-K-V-V-K-G-G-R-R-L-R-F-A-A-L-V-V-V-G-D-R-N-G-R-V-G-F-G-T-G-K-A-Q-E-V-P-E-A-I-R-K-A-V-E-A-A-K-K-N-M-V-E-V-P-M-V-G-T-T-I-P-H-E-V-R-S-E-F-G-G-A-K-V-L-L-K-P-A-V-E-G-A-G-V-A-A-G-G-A-V-R-A-V-I-E-L-A-G-V-A-D-I-T-S-K-S-L-G-S-N-T-P-I-N-I-V-R-A-T-V-E-G-L-K-Q-L-K-R-A-E-E-V-A-A-L-R-G-I-S-V-S-D-L-A


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-S-K-P-D-K-N-K-I-R-Q-K-R-H-R-R-V-R-G-K-L-S-G-T-A-D-R-P-R-L-N-I-F-R-S-N-T-G-I-Y-A-Q-V-I-D-D-V-A-G-V-T-L-A-S-A-S-T-L-D-K-E-V-S-N-G-T-K-T-E-Q-A-V-V-V-G-K-L-V-A-E-R-A-V-A-K-G-I-S-E-V-V-F-D-R-G-G-Y-L-Y-H-G-R-V-K-A-L-A-D-S-A-R-E-N-G-L-K-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-N-K-V-I-T-L-P-A-G-V-E-I-I-N-K-D-N-V-V-T-V-K-G-P-K-G-E-L-T-R-E-F-N-K-N-I-G-I-T-V-E-G-T-E-V-T-V-T-R-P-N-D-S-K-E-M-K-T-I-H-G-T-T-R-A-N-L-N-N-M-V-V-G-V-S-E-G-F-K-K-A-L-E-M-R-G-V-G-Y-R-A-Q-L-Q-G-S-K-L-V-L-S-V-G-K-S-H-Q-D-E-V-E-A-P-E-G-V-T-F-E-V-P-T-P-T-T-I-N-V-I-G-I-N-K-E-S-V-G-Q-T-A-A-Y-V-R-S-L-R-S-P-E-P-Y-K-G-K-G-I-R-Y-V-G-E-F-V-R-R-K-E-G-K-T-G-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-V-M-T-D-P-I-A-D-F-L-T-R-I-R-N-A-N-Q-A-K-H-E-V-L-E-V-P-A-S-N-I-K-K-G-I-A-D-I-L-K-R-E-G-F-V-K-N-V-E-V-I-E-D-D-K-Q-G-I-I-R-V-F-L-K-Y-G-Q-N-G-E-R-V-I-T-N-L-K-R-I-S-K-P-G-L-R-V-Y-T-K-H-E-D-M-P-K-V-L-N-G-L-G-I-A-I-V-S-T-S-E-G-L-L-T-D-K-E-A-R-Q-K-N-V-G-G-E-V-L-A-Y-I-W


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-M-I-A-K-N-K-R-P-A-K-F-S-T-Q-A-Y-T-R-C-E-K-C-G-R-P-H-S-V-Y-R-K-F-Q-L-C-R-V-C-F-R-D-L-A-Y-K-G-Q-V-P-G-V-T-K-A-S-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-N-R-L-K-E-K-Y-T-N-E-V-V-P-A-L-T-E-K-F-N-Y-S-S-V-M-A-V-P-K-V-E-K-I-V-L-N-M-G-V-G-D-A-V-S-N-A-K-N-L-E-K-A-A-A-E-L-A-L-I-S-G-Q-K-P-L-I-T-K-A-K-K-S-I-A-G-F-R-L-R-E-G-V-A-I-G-A-K-V-T-L-R-G-E-R-M-Y-E-F-L-D-K-L-V-S-V-S-L-P-R-V-R-D-F-H-G-V-P-T-K-S-F-D-G-R-G-N-Y-T-L-G-V-K-E-Q-L-I-F-P-E-I-N-F-D-D-V-D-K-V-R-G-L-D-I-V-I-V-T-T-A-N-T-D-E-E-S-R-E-L-L-K-G-L-G-M-P-F-A-K


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-F-V-K-K-G-D-K-V-R-V-I-A-G-K-D-K-G-T-E-A-V-V-L-K-A-L-P-K-V-N-K-V-V-V-E-G-V-A-L-I-K-K-H-Q-K-P-N-N-E-N-P-Q-G-A-I-V-E-K-E-A-P-I-H-V-S-N-V-Q-V-L-D-K-N-G-V-A-G-R-V-G-Y-K-V-V-D-G-K-K-V-R-Y-N-K-K-S-G-E-V-L-D


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-R-L-K-V-A-D-N-S-G-A-R-E-I-L-T-I-K-V-L-G-G-S-G-R-K-F-A-N-I-G-D-V-I-V-A-S-V-K-Q-A-T-P-G-G-A-V-K-K-G-D-V-V-K-A-V-I-V-R-T-K-T-G-A-R-R-P-D-G-S-Y-I-K-F-D-D-N-A-A-V-I-I-R-D-D-K-T-P-R-G-T-R-I-F-G-P-V-A-R-E-L-R-E-G-G-Y-M-K-I-V-S-L-A-P-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-E-R-N-Q-R-K-T-L-Y-G-R-V-V-S-D-K-M-D-K-T-I-T-V-V-V-E-T-K-R-N-H-P-V-Y-G-K-R-I-N-Y-S-K-K-Y-K-A-H-D-E-N-N-V-A-K-E-G-D-I-V-R-I-M-E-T-R-P-L-S-A-T-K-R-F-R-L-V-E-V-V-E-K-A-V-I-I


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-V-P-K-R-V-K-H-R-R-E-F-R-G-K-M-R-G-E-A-K-G-G-K-E-V-S-F-G-E-Y-G-L-Q-A-T-T-S-H-W-I-T-N-R-Q-I-E-A-A-R-I-A-M-T-R-Y-M-K-R-G-G-K-V-W-I-K-I-F-P-H-K-S-Y-T-A-K-A-I-G-V-R-M-G-S-G-K-G-A-P-E-G-W-V-A-P-V-K-R-G-K-V-M-F-E-I-A-G-V-S-E-E-V-A-R-E-A-L-R-L-A-S-H-K-L-P-V-K-C-K-F-V-K-R-E-A-E


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-A-E-I-T-S-A-K-A-M-A-R-T-V-R-V-S-P-R-K-T-R-L-V-L-D-L-I-R-G-K-N-V-A-D-A-I-A-I-L-K-F-T-P-N-K-A-A-R-V-I-E-K-T-L-N-S-A-I-A-N-A-E-N-N-F-G-L-E-K-A-N-L-V-V-S-E-T-F-A-N-E-G-P-T-M-K-R-F-R-P-R-A-K-G-S-A-S-P-I-N-K-R-T-T-H-V-T-V-V-V-S-E-K


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-K-M-I-V-G-L-G-N-P-G-S-K-Y-N-D-T-K-H-N-I-G-F-M-A-V-D-R-I-V-K-D-L-D-V-N-F-T-E-D-K-N-F-K-A-E-I-G-S-D-F-I-N-G-E-K-I-Y-F-I-K-P-T-T-F-M-N-N-S-G-I-A-V-K-A-L-L-T-Y-Y-N-I-S-I-K-D-M-I-I-I-Y-D-D-L-D-M-E-V-G-K-I-R-F-R-Q-K-G-S-A-G-G-H-N-G-I-K-S-I-I-A-H-L-G-T-Q-E-F-D-R-I-K-V-G-I-G-R-P-N-G-R-M-T-V-I-N-H-V-L-G-K-F-D-K-N-D-E-I-M-I-L-N-T-L-D-K-V-D-N-A-V-N-Y-Y-L-Q-T-N-D-F-Q-K-T-M-Q-K-Y-N-G-L-K


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-N-F-N-A-T-L-I-G-Q-T-V-A-F-I-I-F-V-W-F-C-M-K-F-V-W-P-P-L-M-N-A-I-E-A-R-Q-K-R-I-A-D-G-L-A-D-A-D-R-A-V-K-D-L-E-L-A-Q-A-K-A-T-D-Q-L-K-E-A-K-V-T-A-N-E-I-I-E-Q-A-N-K-R-K-A-Q-I-V-E-E-A-K-T-E-A-D-A-E-R-A-K-I-I-A-Q-G-K-A-E-I-E-A-E-R-N-R-V-K-E-D-L-R-K-Q-V-A-T-L-A-I-M-G-A-E-K-I-L-E-R-S-I-D-P-A-A-H-S-D-I-V-N-K-L-V-A-E-I


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-A-E-L-T-T-I-A-R-P-Y-A-K-A-A-F-D-I-A-V-E-H-N-A-V-D-N-W-A-E-M-L-T-F-A-A-L-V-S-E-N-E-T-M-K-P-L-L-T-G-S-L-A-S-T-K-L-A-A-L-F-I-S-V-C-G-E-Q-I-N-E-Q-G-Q-N-L-I-K-V-M-A-E-N-G-R-L-K-V-L-P-A-V-S-E-L-F-A-Q-Y-R-N-E-W-A-K-E-V-E-A-D-V-V-S-A-A-E-L-S-S-E-Q-Q-Q-Q-I-S-I-S-L-E-K-R-L-A-R-K-V-K-L-N-C-S-T-D-A-A-L-I-A-G-V-I-I-K-A-G-D-L-V-I-D-G-S-V-R-G-K-L-S-R-L-S-E-K-L-Q-S


### FUNCTION A GTPase-activating protein  that modifies Der/EngA GTPase function May play a role in ribosome biogenesis ### SEQUENCE -M-S-R-S-K-K-T-R-K-G-G-E-N-S-P-K-Q-Q-P-R-V-K-K-Q-D-R-A-E-V-T-G-K-R-A-E-K-G-N-K-S-G-S-R-H-N-E-A-L-I-Q-A-Q-A-P-Q-K-K-A-A-Q-K-K-D-P-R-H-G-S-K-K-P-V-A-L-A-L-P-T-T-T-E-K-S-A-T-P-K-V-K-Q-P-K-L-T-D-E-Q-K-L-L-K-L-E-E-D-P-R-L-N-Q-L-L-D-M-L-E-E-G-R-N-L-S-D-A-D-Q-K-W-L-D-Q-Q-L-N-K-I-E-A-L-M-I-K-L-G-I-S-D-E-L-E-D-E-A-P-A-K-S-K-A-D-S-D-D-D-L-F-D-R-F-E-S-G-A-E-L-L-K-D-Y-Q-D-K-F


### FUNCTION Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide ### SEQUENCE -M-S-S-F-K-H-L-S-V-N-Q-L-V-Q-M-T-E-A-K-S-V-Q-I-V-D-I-R-D-G-N-S-F-N-N-G-H-I-D-G-A-F-N-L-N-N-E-N-L-A-H-F-I-G-Q-A-D-M-D-R-P-L-V-V-V-C-Y-H-G-I-S-S-Q-N-A-A-Q-Y-L-C-E-Q-G-F-D-D-V-Y-S-L-D-G-G-F-S-A-W-H-E-A-N-A


### FUNCTION Involved in iron-sulfur cluster biogenesis Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins Could also act as a scaffold/chaperone for damaged Fe/S proteins ### SEQUENCE -M-I-T-I-S-D-A-A-Q-A-H-F-V-K-L-L-A-D-Q-P-E-G-T-H-I-R-V-F-V-I-S-P-G-T-A-Q-A-E-C-G-V-S-Y-C-P-P-D-A-V-E-S-D-D-I-E-L-A-F-N-G-F-S-A-M-V-D-E-K-S-A-P-F-L-E-E-A-S-I-D-F-V-T-D-Q-L-G-S-Q-L-T-L-K-A-P-N-A-K-M-R-K-V-A-G-D-A-P-L-V-E-R-I-E-Y-V-I-Q-S-E-I-N-P-Q-L-A-S-H-G-G-N-I-M-L-V-E-I-T-G-E-G-V-A-V-L-Q-F-G-G-G-C-N-G-C-S-Q-V-D-I-T-L-K-D-G-I-E-K-Q-L-L-D-M-F-P-G-E-L-T-G-V-R-D-V-T-D-H-Q-H-G-E-H-S-Y-A


### FUNCTION Involved in iron-sulfur  cluster assembly May act as a regulator of Fe-S biogenesis ### SEQUENCE -M-A-M-T-D-T-E-F-H-Q-L-A-D-D-M-F-Q-A-I-E-T-A-I-E-T-A-I-D-E-Q-D-A-D-V-D-I-D-A-S-G-N-V-L-Q-L-E-F-V-D-G-S-K-I-V-I-N-K-Q-E-P-L-H-E-I-W-V-A-T-R-F-G-G-Y-H-F-G-Y-V-E-G-K-W-L-D-G-R-N-G-G-E-F-M-P-F-V-Q-D-S-I-L-R-Q-S-G-I-E-L-S-L


### FUNCTION This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA ### SEQUENCE -M-K-T-P-I-E-L-K-I-L-D-S-R-I-G-S-E-F-P-L-P-A-Y-A-T-P-G-S-A-G-M-D-L-R-A-M-I-D-T-T-M-T-I-A-P-G-E-T-Q-L-V-P-T-G-I-A-I-H-V-A-D-P-G-L-A-A-L-I-L-P-R-S-G-L-G-H-K-H-G-I-V-L-G-N-L-V-G-L-V-D-S-D-Y-Q-G-P-L-M-V-S-C-W-N-R-S-D-T-P-F-T-L-E-I-G-D-R-L-A-Q-L-V-F-V-P-V-V-Q-A-Q-F-K-L-V-D-E-F-D-S-S-D-R-G-E-G-G-F-G-H-S-G-T-K


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-S-K-P-S-L-T-L-P-R-I-V-L-H-D-L-W-Q-H-K-W-I-L-L-L-A-L-L-V-L-S-N-A-V-A-V-V-Y-T-S-H-V-S-R-K-L-T-T-E-W-D-Q-L-L-Q-E-R-D-R-L-D-I-E-W-R-N-L-L-L-E-E-Q-S-Q-T-E-H-S-R-I-T-R-I-A-S-K-D-L-N-M-S-R-P-L-P-S-E-E-I-V-V-K-V-P


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation ### SEQUENCE -M-F-D-G-I-G-F-M-E-L-L-L-I-G-V-L-G-L-I-V-L-G-P-E-R-L-P-V-A-V-R-S-V-T-S-W-V-R-A-M-K-R-M-A-N-S-V-K-E-E-L-E-Q-E-L-K-I-E-Q-L-H-A-D-L-K-K-A-E-S-K-G-L-S-N-L-S-P-E-L-Q-E-S-I-E-Q-L-K-Q-A-A-Q-S-V-N-R-P-Y-Q-V-Q-D-T-P-S-A-Q-D-N-Q-I-H-N-P-A-S-Q-T-V-S-T-E-A-S-S-T-S-A-S-S-A-P-K-S-E-S-I-Q-G-E-D-P-R-S-N-T-K-A-N-G


### FUNCTION Part of the twin-arginine translocation  system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes TatA could form the protein-conducting channel of the Tat system ### SEQUENCE -M-G-G-I-S-I-W-Q-L-L-I-I-A-L-I-V-V-L-L-F-G-T-K-K-L-R-S-L-G-G-D-L-G-G-A-V-K-G-F-K-N-A-M-S-S-E-E-D-K-K-A-L-E-D-A-E-A-A-K-P-V-Q-T-A-Q-T-V-Q-S-A-Q-P-T-Q-Q-A-T-E-K-K-P-E-S-N-K-E-Q-A


### FUNCTION Globally modulates RNA abundance by binding to RNase E  and regulating its endonucleolytic activity Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome Modulates RNA-binding and helicase activities of the degradosome ### SEQUENCE -M-E-Y-N-T-S-E-L-C-D-M-Y-L-D-V-V-D-V-V-E-P-M-F-S-N-Y-G-G-C-S-S-F-G-G-S-I-S-T-I-K-C-F-E-D-N-G-L-I-T-D-V-L-Q-E-D-G-Q-G-K-V-L-L-V-D-G-G-G-S-L-R-R-A-L-I-D-G-T-I-A-E-L-A-V-S-N-N-W-E-G-I-I-V-Y-G-S-V-R-D-V-D-A-L-E-E-L-D-I-G-I-Q-A-L-A-S-I-P-V-G-A-D-G-N-S-V-G-E-V-D-I-P-V-N-F-G-G-V-T-F-L-P-G-D-H-I-Y-A-D-N-T-G-I-I-L-S-P-E-P-L-D-I-E


### FUNCTION Binds the 23S rRNA ### SEQUENCE -M-K-P-G-I-H-P-E-Y-A-E-I-T-A-N-C-T-C-G-N-V-I-K-V-N-S-T-V-G-K-D-L-H-L-D-V-C-G-A-C-H-P-F-Y-T-G-T-Q-K-V-V-D-T-G-G-R-I-D-K-F-N-K-R-F-G-M-L-G-K-K


### FUNCTION This regulatory protein, when combined with SAM  represses the expression of the methionine regulon and of enzymes involved in SAM synthesis ### SEQUENCE -M-T-E-W-N-G-E-Y-I-S-P-Y-A-E-H-G-K-K-N-E-Q-V-K-K-I-T-V-S-I-P-L-K-V-L-K-V-L-T-D-E-R-T-R-R-Q-V-N-N-L-R-H-A-T-N-S-E-L-L-C-E-A-F-L-H-A-Y-T-G-Q-P-L-P-D-D-A-D-L-S-K-E-C-P-D-S-I-P-A-E-A-K-R-L-M-D-E-M-G-I-E-W-E-D-M-E


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-K-T-F-T-A-T-P-E-T-V-T-R-D-W-F-V-V-D-A-D-G-K-T-L-G-R-I-A-T-E-I-A-L-R-L-R-G-K-H-K-P-E-Y-T-P-H-V-D-T-G-D-Y-I-I-V-I-N-A-E-K-V-T-V-T-G-N-K-A-Q-G-K-T-Y-Y-S-H-S-G-F-P-G-G-I-K-Q-I-S-F-E-K-L-Q-A-H-K-P-E-M-I-I-E-K-A-V-K-G-M-L-P-K-G-P-L-G-R-A-M-F-R-K-L-K-V-Y-A-G-A-E-H-N-H-A-A-Q-Q-P-Q-V-L-D-I


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-I-V-F-M-V-H-P-D-Q-S-E-Q-V-P-G-M-I-E-R-Y-T-G-A-I-T-E-A-N-G-K-I-H-R-L-E-D-W-G-R-R-Q-L-A-Y-P-I-Q-D-L-H-K-A-H-Y-V-L-M-N-V-E-A-P-A-E-T-I-E-E-L-E-T-A-F-R-F-N-D-A-V-L-R-N-M-V-M-R-T-K-G-A-I-T-E-A-S-P-M-A-K-A-K-D-E-R-D-S-R-R-G-P-A-G-D-R-S-Y-D-E-A-N-A-E-E-I-A-E


### FUNCTION Binds single-stranded DNA at the primosome assembly site ### SEQUENCE -M-T-T-N-N-L-V-L-S-G-T-I-T-R-S-R-R-F-K-S-P-A-G-I-A-H-S-V-I-M-L-E-H-K-S-Q-R-Y-E-A-D-M-L-R-N-V-Y-V-Q-I-Q-V-I-L-S-G-P-R-F-E-S-V-A-D-N-L-K-A-G-V-E-V-Q-V-Q-G-F-M-T-L-Q-Q-G-R-N-G-Q-N-R-L-V-I-H-A-E-N-V-E-L-K-T


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-R-Y-F-R-R-R-K-F-C-R-F-T-A-E-G-V-A-E-I-D-Y-K-D-I-V-T-L-K-N-Y-I-T-E-S-G-K-I-V-P-S-R-I-T-G-T-S-A-K-Y-Q-R-Q-L-A-R-A-I-K-R-A-R-Y-L-S-L-L-P-Y-T-D-L-H-Q


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-N-V-I-L-L-D-K-I-A-N-L-G-N-L-G-D-Q-V-A-V-K-A-G-Y-A-R-N-Y-L-L-P-Q-G-K-A-V-V-A-N-E-S-N-V-K-V-F-E-A-R-R-A-E-L-E-A-K-L-A-A-D-L-A-A-A-N-Q-R-A-E-K-I-A-A-L-E-A-V-V-I-A-S-K-A-G-D-E-G-K-L-F-G-S-V-G-N-R-D-I-A-D-A-V-T-A-A-G-V-E-L-A-K-S-E-V-R-L-P-L-G-A-L-R-T-T-G-D-F-E-V-E-V-Q-L-H-T-E-V-K-A-V-V-K-V-S-I-V-A-E-A


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-Y-A-V-F-Q-S-G-G-K-Q-H-R-V-A-P-G-H-T-V-R-L-E-K-L-E-V-A-T-G-S-T-V-E-F-D-Q-V-L-L-I-A-D-G-E-K-V-H-V-G-A-P-L-V-A-G-G-K-V-V-A-E-V-V-S-H-G-R-G-E-K-V-T-I-V-K-F-R-R-R-K-H-H-D-K-K-L-G-H-R-Q-W-F-T-E-V-K-I-T-A-I-N-A


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-A-N-S-K-S-A-K-K-R-A-L-Q-S-E-K-R-R-Q-H-N-A-S-R-R-S-M-L-R-T-Y-V-K-K-V-I-A-A-I-R-A-G-D-H-K-T-A-T-E-A-F-A-A-A-Q-P-I-V-D-R-M-A-T-K-G-L-I-H-K-N-K-A-A-R-H-K-A-R-L-N-A-K-I-K-A-L-V-A


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-H-C-P-F-C-S-A-T-D-T-K-V-I-D-S-R-L-V-A-E-G-H-Q-V-R-R-R-R-E-C-T-E-C-H-E-R-F-T-T-F-E-G-A-E-L-V-M-P-R-V-I-K-R-D-G-T-R-Q-P-F-D-E-E-K-L-Q-A-G-M-L-R-A-V-E-K-R-P-V-S-M-D-E-I-E-Q-A-L-S-K-I-K-S-T-L-R-A-T-G-E-R-E-V-P-S-E-M-I-G-N-L-M-M-E-Q-L-M-S-L-D-K-V-A-Y-I-R-F-A-S-V-Y-R-A-F-E-D-V-S-E-F-G-E-A-I-A-K-L-Q-K


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-K-P-S-E-R-R-K-A-R-R-L-A-V-Q-A-I-Y-S-W-Q-L-S-G-N-N-I-A-D-V-E-H-E-F-L-T-E-Q-S-L-D-G-V-D-V-A-Y-F-R-E-L-F-A-G-V-A-T-K-K-T-Q-L-D-E-L-I-I-P-H-L-D-R-P-I-D-E-V-S-P-V-E-K-A-I-V-R-L-A-A-Y-E-L-T-F-R-K-D-V-P-F-K-V-A-I-N-E-A-I-E-L-A-K-A-F-G-A-D-E-S-H-K-F-V-N-G-L-L-D-K-L-V-A-R-K


### FUNCTION Essential cell division protein May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ### SEQUENCE -M-K-F-F-V-I-T-L-I-V-L-L-G-L-L-Q-Y-R-L-W-S-G-D-N-S-L-P-E-Y-F-V-L-Q-K-Q-I-A-A-Q-Q-D-G-N-A-K-L-N-E-R-N-Q-V-L-K-E-E-I-I-D-L-K-S-G-T-E-A-I-E-E-R-A-R-N-E-L-G-M-V-K-E-G-E-T-F-Y-R-V-V-G-G-D-R-A-V-S-S-P-S-Q


### FUNCTION A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems Usually binds in the 5'-UTR ### SEQUENCE -M-L-I-L-T-R-R-V-G-E-T-L-M-I-G-D-E-V-T-V-T-V-L-G-V-K-G-N-Q-V-R-I-G-V-N-A-P-K-E-V-S-V-H-R-E-E-I-Y-Q-R-I-Q-S-E-K-S-G-T-P-S-E-G-G-N-F


### FUNCTION Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes ### SEQUENCE -M-A-R-T-V-N-C-V-H-L-N-K-E-A-D-G-L-D-F-Q-L-Y-P-G-D-L-G-K-R-I-F-D-N-I-S-K-E-A-W-G-L-W-Q-K-K-Q-T-M-L-I-N-E-K-K-L-N-M-M-N-V-D-D-R-K-F-L-E-A-Q-M-T-S-F-L-F-E-G-K-D-V-E-I-E-G-F-V-P-E-K-D-Q-D


### FUNCTION Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ### SEQUENCE -M-N-A-K-T-V-L-G-F-D-F-G-T-K-S-I-G-V-A-V-G-Q-Q-I-T-A-S-A-T-P-L-L-S-I-K-A-V-D-G-I-P-N-W-E-E-I-A-K-L-I-Q-E-W-Q-P-D-L-V-V-V-G-L-P-L-N-M-D-G-T-E-Q-E-M-T-H-R-A-R-K-F-A-N-R-L-N-A-K-F-G-V-K-I-F-T-Q-D-E-R-L-T-T-T-D-A-K-A-R-L-F-E-L-G-G-Y-K-A-L-T-K-G-Q-V-D-A-V-S-A-V-L-I-I-E-S-Y-F-E-N-H-F-G-D


### FUNCTION Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids ### SEQUENCE -M-M-T-P-Q-L-I-L-A-S-T-S-V-Y-R-Q-A-L-L-R-K-L-G-L-P-F-E-Y-C-D-P-N-I-D-E-T-P-I-A-N-E-S-A-Q-A-L-V-L-R-L-A-Q-A-K-A-E-A-G-A-K-Y-F-P-D-G-L-I-I-G-S-D-Q-V-A-V-I-D-S-K-I-I-G-K-P-L-N-R-D-N-A-I-Q-Q-L-S-Q-A-S-G-K-T-I-T-F-Y-T-G-L-A-L-Y-N-A-Q-T-G-E-I-N-A-Q-V-E-P-F-T-V-H-F-R-H-L-A-A-S-Q-I-S-A-Y-V-D-K-E-Q-P-F-Y-C-A-G-S-F-K-S-E-G-L-G-I-A-L-F-S-R-L-E-G-R-D-P-N-T-L-V-G-L-P-L-I-L-L-T-E-M-L-L-S-Q-G-I-D-V-L-A


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-S-N-I-E-E-R-V-K-K-I-I-V-E-Q-L-G-V-K-E-E-D-V-K-P-A-A-S-F-V-D-D-L-G-A-D-S-L-D-T-V-E-L-V-M-A-L-E-E-E-F-D-T-E-I-P-D-E-E-A-E-K-I-T-T-V-Q-A-A-I-D-Y-V-S-K-N-Q


### FUNCTION Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ### SEQUENCE -M-G-K-T-G-N-I-E-H-V-E-E-R-V-E-S-E-L-M-P-P-S-M-Y-K-V-I-L-N-N-D-D-Y-T-P-M-D-F-V-I-E-V-L-Q-I-F-F-R-K-N-E-Q-E-A-T-D-I-M-L-T-I-H-H-Q-G-K-G-I-C-G-I-F-P-F-G-I-A-E-T-K-V-I-Q-V-N-Q-F-A-R-Q-N-Q-H-P-L-L-C-S-L-E-K-A


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-D-N-I-E-M-Q-G-T-I-L-E-T-L-P-N-T-M-F-R-V-E-L-E-N-G-H-V-V-I-A-H-I-S-G-K-M-R-K-N-Y-I-R-I-L-T-G-D-K-V-T-V-Q-L-T-P-Y-D-L-T-K-G-R-I-V-F-R-A-R


### FUNCTION Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ ### SEQUENCE -M-L-L-L-P-Q-K-D-W-H-W-K-Y-N-D-S-Y-G-V-L-S-V-S-L-G-S-E-I-E-F-L-T-A-Y-K-A-K-S-L-I-P-D-A-L-S-S-M-E-F-N-I-S-H-A-K-F-Y-M-S-L-L-D-K-L-P-K-T-L-T-L-T-D-A-A-V-V-Q-I-A-L-N-A-T-A-A-H-F-M-L-T-P-Q-M-P-K-S-W-F-F-D-T-S-E-V-C-V-Y-S-D-V-G-K-V-F-E-L-K-C-Q-K-Q-R-A-L-V-L-V-V-E-N-T-L-Q-S-A-L-V-M-L-L-S-P-E-C-V-L-S-G-A-K-T-L-G-Q-F-E-T-I-K-V-M-H-N-R-L-H-P-L-R-A-Q-R-H-V-V-A-A


### FUNCTION Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell ### SEQUENCE -M-S-L-L-D-Y-F-K-S-K-K-K-P-S-T-A-V-M-A-K-E-R-L-Q-I-I-V-A-H-Q-R-G-Q-R-D-T-P-D-Y-F-P-Q-M-K-Q-E-I-I-A-V-I-R-K-Y-V-Q-I-S-D-D-Q-V-S-V-Q-L-D-Q-N-D-D-N-L-S-V-L-E-L-N-V-T-L-P-D-R


### FUNCTION Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane ### SEQUENCE -M-S-E-Y-L-L-L-L-I-S-T-V-L-V-N-N-F-V-L-V-K-F-L-G-L-C-P-F-M-G-V-S-S-K-L-E-S-A-I-G-M-S-M-A-T-T-F-V-L-T-L-A-S-I-L-S-Y-L-V-N-Q-Y-L-L-L-P-F-D-L-G-Y-L-R-T-M-S-F-I-L-V-I-A-V-V-V-Q-F-T-E-M-V-V-Q-K-T-S-A-A-L-H-R-A-L-G-I-Y-L-P-L-I-T-T-N-C-A-V-L-G-V-A-L-L-N-V-N-E-K-H-D-F-I-Q-S-A-I-Y-G-F-G-A-A-V-G-F-S-L-V-L-I-L-F-S-A-M-R-E-R-L-A-A-A-D-V-P-E-P-F-K-G-G-A-I-A-M-I-T-A-G-L-M-S-L-A-F-M-G-F-T-G-L-V-K


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-T-K-S-E-L-I-E-K-L-A-T-R-Q-S-Q-L-S-A-K-E-V-E-G-A-I-K-E-M-L-E-Q-M-A-T-T-L-E-S-G-D-R-I-E-I-R-G-F-G-S-F-S-L-H-Y-R-A-P-R-T-G-R-N-P-K-T-G-S-S-V-E-L-E-G-K-Y-V-P-H-F-K-P-G-K-E-L-R-E-R-V-D-A-V-N-V


### FUNCTION Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins Repression is relieved when the region becomes fully methylated ### SEQUENCE -M-K-Y-I-E-V-D-E-E-L-Y-R-H-I-A-S-K-T-E-R-I-G-E-S-A-S-D-I-L-R-R-L-L-G-L-S-V-D-T-V-E-Q-A-Q-P-Q-A-I-S-Q-P-S-L-E-A-A-T-P-E-P-Q-F-V-P-Q-V-E-T-F-V-A-A-A-D-F-H-Q-L-V-D-E-H-K-L-E-Q-Q-K-G-A-V-G-R-F-L-F-L-L-E-S-L-Y-Q-L-N-K-T-Q-F-A-Q-I-L-Q-I-Q-G-R-D-R-L-Y-F-A-R-S-R-E-E-L-L-K-A-S-A-T-A-N-P-K-E-I-G-Q-T-G-F-W-V-T-T-N-N-N-T-A-K-K-R-A-I-L-A-E-A-L-V-Q-F-G-C-D-A-E-I-A-N-G-I-A-E-R-V


### FUNCTION General inhibitor of family S1 serine proteases ### SEQUENCE -M-K-L-P-Q-L-C-H-L-A-A-V-P-L-A-F-T-L-L-S-F-N-A-S-A-V-S-P-P-H-P-T-G-L-D-A-P-M-I-S-V-S-S-M-N-A-N-N-Y-A-P-V-E-T-V-K-M-F-P-A-P-K-K-G-M-V-Q-H-I-L-T-L-P-K-L-E-N-E-T-D-Y-M-V-E-I-Q-I-G-Q-T-Q-L-V-D-C-N-K-H-G-L-N-G-Q-L-K-E-L-T-V-E-G-W-G-Y-N-Y-Y-Q-V-D-E-I-S-E-G-P-S-T-M-M-A-C-F-E-L-A-K-K-E-A-F-V-Q-I-P-D-E-L-T-L-R-Y-D-S-R-L-P-K-V-F-Y-L-P-E-G-A-E-L-R-F-R-T-W-K-A-D-S-T-Y-Q-Y-S-K


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-N-L-L-L-V-A-L-G-G-S-I-G-A-V-F-R-Y-L-I-S-I-F-M-I-Q-V-F-G-S-S-F-P-F-G-T-L-L-V-N-V-L-G-S-F-L-M-G-V-I-Y-A-L-G-Q-M-S-H-I-S-P-E-F-K-A-L-I-G-V-G-L-L-G-A-L-T-T-F-S-T-F-S-N-E-T-L-L-L-M-Q-E-G-D-W-L-K-A-A-L-N-V-V-L-N-L-S-L-C-L-F-M-V-Y-L-G-Q-Q-L-V-F-S-R-I


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-P-R-V-K-R-G-V-T-A-R-A-R-H-K-K-V-L-K-L-A-K-G-Y-Y-G-A-R-S-R-T-Y-R-V-A-V-Q-A-V-T-K-A-G-Q-Y-A-Y-R-D-R-R-Q-K-K-R-Q-F-R-Q-L-W-I-A-R-I-N-A-A-A-R-Q-N-G-L-S-Y-S-R-F-I-N-G-L-K-K-A-S-I-E-I-D-R-K-I-L-A-D-I-A-V-F-D-K-V-V-F-A-T-L-V-E-K-A-K-E-A-L-N


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-K-I-K-K-T-A-G-R-Q-L-A-P-N-R-I-N-E-E-I-T-G-V-P-E-V-R-L-T-G-I-D-G-E-A-I-G-V-V-S-I-R-D-A-Q-N-L-A-D-E-A-G-V-D-L-V-E-I-S-P-N-A-E-P-P-V-C-R-I-M-D-Y-G-K-F-L-F-D-K-A-K-S-A-K-E-Q-K-K-K-Q-K-Q-V-Q-V-K-E-I-K-F-R-P-G-T-D-E-N-D-Y-Q-V-K-L-R-N-L-I-R-F-L-E-D-G-D-K-A-K-I-T-L-R-F-R-G-R-E-M-A-H-Q-N-L-G-M-D-L-L-N-R-I-K-T-D-L-D-E-Y-A-V-V-E-S-F-P-K-M-E-G-R-Q-A-I-M-V-L-A-P-K-K-K


### FUNCTION Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins Seems to help targeting proteins to be folded toward HscA ### SEQUENCE -M-N-Y-F-E-L-F-K-F-P-P-T-F-D-I-D-T-A-V-L-A-D-R-Y-R-E-L-Q-R-A-V-H-P-D-K-F-A-N-D-T-E-Q-Q-R-L-L-S-V-Q-R-T-A-Q-V-N-D-G-Y-Q-T-L-K-D-P-I-R-R-A-E-H-M-L-S-L-R-G-I-D-L-S-H-E-T-T-T-V-K-D-T-A-F-L-M-Q-Q-M-E-W-R-E-A-L-E-D-I-R-E-S-I-D-H-Q-A-I-I-N-E-L-Y-D-S-F-A-A-Y-R-L-K-L-T-K-L-L-A-A-Q-L-S-S-G-S-D-E-D-A-L-L-A-A-D-Q-V-R-K-L-K-F-M-A-K-L-Q-D-E-L-T-R-I-E-D-A-L-L-D


### FUNCTION This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ### SEQUENCE -M-S-Y-T-I-T-A-Q-T-R-T-E-I-G-K-G-S-S-R-R-L-R-H-A-G-K-V-P-A-V-I-Y-G-A-G-K-E-P-V-S-I-V-F-D-H-K-D-I-I-N-A-Q-A-N-D-D-F-Y-T-S-V-V-T-I-V-L-D-G-K-E-V-G-V-R-A-Q-A-M-Q-R-H-A-F-K-P-I-I-E-H-V-D-F-V-Y-A


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-Y-S-I-V-S-A-L-I-E-Q-C-E-Q-Y-A-K-A-N-Q-A-T-K-V-T-R-V-E-I-K-L-G-V-M-S-G-V-E-P-A-L-L-Q-T-A-F-E-T-F-K-L-D-G-I-C-R-E-A-K-L-C-M-T-L-Q-P-L-V-I-K-C-A-D-C-Q-Q-E-S-V-L-D-E-R-S-I-V-C-P-A-C-N-S-Y-H-T-R-V-L-D-G-E-E-M-L-L-M-Q-L-E-M-E-Q-A-E-D-A


### FUNCTION This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control ### SEQUENCE -M-A-L-T-K-A-E-M-A-E-H-L-F-E-T-L-G-I-N-K-R-V-A-K-E-M-V-E-S-F-F-E-E-I-R-G-A-L-E-S-G-E-Q-V-K-L-S-G-F-G-N-F-D-L-R-D-K-N-Q-R-P-G-R-N-P-K-T-G-E-D-I-P-I-S-A-R-R-V-V-T-F-R-P-G-Q-K-L-K-T-R-V-E-A-A-N-T-G-K


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-K-F-S-P-L-L-D-E-L-I-Q-S-L-R-C-L-P-G-V-G-P-K-S-A-Q-R-M-A-F-Q-L-L-E-R-D-R-K-A-G-L-K-L-A-A-A-L-S-S-A-M-S-D-I-G-H-C-Q-S-C-R-T-Y-T-E-E-T-L-C-P-I-C-A-S-H-K-R-G-S-S-S-T-I-C-V-V-E-T-P-A-D-V-L-A-I-E-A-G-G-H-F-T-G-R-Y-F-V-L-L-G-H-L-S-P-L-D-G-V-G-P-E-E-L-G-L-A-L-L-E-R-H-L-A-S-G-D-V-A-E-L-I-L-A-T-N-P-T-V-E-G-E-A-T-A-H-F-I-A-D-M-A-R-R-H-K-V-L-I-S-R-I-A-H-G-V-P-V-G-G-E-L-E-Y-V-D-S-T-T-L-A-L-S-F-N-G-R-I-P-L


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-F-G-K-G-G-M-G-N-L-M-K-Q-A-Q-M-M-Q-E-R-M-A-K-M-Q-E-E-I-A-R-M-E-M-V-G-E-S-G-A-G-L-V-K-V-T-M-T-G-A-H-T-V-R-K-V-E-I-Y-P-S-L-M-E-D-D-K-E-M-L-E-D-L-I-A-A-A-C-N-D-A-A-R-I-I-E-E-N-Q-K-A-K-M-A-E-V-T-G-G-M-Q-L-P-P-G-M-K-M-P-F


### FUNCTION Catalyzes the hydrolysis of N ### SEQUENCE -M-L-T-E-I-T-F-F-E-R-F-E-H-D-I-L-M-G-K-K-T-I-T-L-R-N-E-A-E-S-H-V-I-P-G-Q-I-L-P-V-S-T-F-E-T-H-R-W-F-C-D-I-Q-V-L-E-V-T-P-I-T-L-S-G-L-T-T-L-H-A-Q-Q-E-N-M-T-L-A-E-L-R-L-V-I-A-E-I-Y-P-D-L-E-Q-L-Y-M-I-R-F-K-V-L-T-K


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-I-A-D-I-K-K-D-A-Q-E-R-M-G-K-C-V-D-A-T-K-N-Q-M-A-K-V-R-T-G-R-A-H-P-S-L-L-D-S-I-Q-V-S-Y-Y-G-T-M-T-P-L-N-Q-V-A-N-V-G-V-E-D-A-R-T-L-S-V-T-V-F-D-R-S-A-I-Q-A-V-E-K-A-I-M-S-S-D-L-G-L-N-P-M-S-A-G-A-T-L-R-I-P-L-P-A-L-T-E-E-R-R-K-D-F-I-K-V-V-R-A-E-A-E-G-G-R-V-A-I-R-N-V-R-R-D-A-I-S-D-V-K-K-L-E-K-A-K-E-C-T-E-D-D-V-R-R-F-E-D-E-V-Q-K-F-T-D-A-H-I-K-K-V-D-E-I-L-A-A-K-E-I-E-L-M-E-V


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-V-K-K-N-S-K-K-A-A-P-A-T-I-A-R-N-K-R-A-T-F-E-Y-R-F-E-E-K-M-E-A-G-L-S-L-M-G-W-E-V-K-S-I-R-M-G-K-V-N-L-S-D-C-Y-V-F-L-K-N-G-E-A-F-M-H-G-C-T-I-I-P-L-N-T-A-S-T-H-V-V-C-D-P-I-R-L-K-K-L-L-L-S-R-K-E-L-D-K-L-A-G-L-V-E-R-Q-G-Y-S-I-I-P-I-S-M-Y-W-R-K-G-A-W-V-K-V-E-I-G-L-G-K-G-K-K-D-H-D-K-R-E-D-T-K-A-R-E-W-E-V-E-K-A-R-V-M-K-K-E-K-T-R-G


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-N-N-I-I-K-M-L-N-D-E-Q-M-K-Q-D-V-P-A-F-G-A-G-D-T-V-V-V-Q-V-R-V-K-E-G-D-K-E-R-L-Q-A-F-E-G-V-V-I-A-K-R-N-R-G-L-H-S-A-F-T-V-R-K-I-S-N-G-E-G-V-E-R-A-F-Q-T-H-S-P-L-I-A-S-I-E-V-K-R-R-G-R-V-R-R-A-K-L-Y-Y-L-R-D-R-S-G-K-S-A-R-I-R-E-K-L-A-T-K


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-S-S-N-Q-Q-P-V-V-L-G-K-L-G-S-C-H-G-I-K-G-W-L-K-I-T-A-Y-T-D-S-V-E-G-I-F-D-Y-S-P-W-L-I-K-E-N-G-E-W-R-E-V-K-V-I-Q-W-R-Y-Q-G-K-A-V-V-A-E-L-E-G-V-T-T-R-E-R-A-Q-M-L-T-N-C-E-I-G-I-L-P-Q-Q-M-N-A-L-P-E-D-E-F-Y-W-R-D-L-I-G-C-E-V-I-N-T-T-G-Y-N-M-G-I-V-D-Q-I-V-E-T-G-S-N-D-V-L-L-V-K-A-N-A-K-D-S-F-G-K-V-E-R-M-V-P-F-V-P-G-Q-F-I-L-K-V-D-V-Q-G-K-Q-I-L-V-D-W-D-P-D-F


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-A-I-V-G-L-G-T-D-I-V-E-I-E-R-I-S-A-H-V-A-R-S-G-D-K-L-A-K-R-V-L-T-E-A-E-F-E-I-Y-Q-Q-H-S-Q-P-S-R-Y-L-A-K-R-F-A-A-K-E-A-A-A-K-A-L-G-T-G-I-G-R-G-V-S-F-Q-H-I-H-I-G-N-T-P-D-G-A-P-T-I-D-F-T-E-G-A-Q-Q-R-L-T-L-L-N-G-V-V-G-H-I-S-I-A-D-E-K-S-Y-A-I-A-T-V-I-L-E-S-R


### FUNCTION An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins Plays an essential role in the assembly of succinate dehydrogenase  of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well ### SEQUENCE -M-E-L-M-N-I-A-R-V-R-W-A-C-R-R-G-M-L-E-L-D-V-L-F-Q-P-F-V-D-N-V-Y-Q-D-L-S-D-E-D-K-V-L-F-I-R-L-L-E-C-E-D-P-E-L-F-A-W-F-M-G-H-E-V-C-P-D-P-E-L-A-R-M-V-V-Q-V-R-G-R-A-A-P


### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-S-D-G-F-R-A-N-V-G-I-I-I-C-N-R-Y-G-Q-V-M-W-A-R-R-F-G-Q-H-S-W-Q-F-P-Q-G-G-V-D-D-G-E-S-A-E-E-A-M-Y-R-E-L-Y-E-E-V-G-L-R-P-E-H-V-T-V-L-T-S-T-R-S-W-L-R-Y-R-L-P-K-R-L-V-R-Q-D-S-K-P-V-C-I-G-Q-K-Q-K-W-F-L-L-Q-L-K-S-Q-D-S-A-I-N-L-S-S-S-G-H-P-E-F-D-D-W-R-W-V-S-Y-W-Y-P-V-R-Q-V-V-S-F-K-R-D-V-Y-R-K-V-M-K-E-F-A-V-T-A-L-S-F-Q-T-Q-E-I-P-K-K-R-V-R-Q-K-T-T-G


### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-T-D-Q-A-D-A-T-M-P-I-K-F-T-D-A-A-A-A-K-V-K-G-L-L-E-E-E-Q-N-P-A-L-K-L-R-V-Y-V-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-E-K-V-N-E-G-D-F-T-V-E-K-Q-G-V-Q-L-V-V-D-P-M-S-L-Q-Y-L-V-G-G-E-V-D-Y-T-S-G-L-E-G-S-R-F-F-V-K-N-P-N-A-T-T-T-C-G-C-G-A-S-F-S-V


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-S-L-S-T-E-A-K-A-K-I-L-A-E-F-G-R-G-A-N-D-T-G-S-T-E-V-Q-V-A-L-L-T-A-Q-I-N-H-L-Q-D-H-F-K-E-H-I-H-D-H-H-S-R-R-G-L-L-R-M-V-S-A-R-R-K-L-L-A-Y-L-K-R-T-E-A-V-R-Y-N-E-L-I-Q-K-L-G-L-R-R


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-A-K-E-F-S-R-T-R-R-I-G-Q-Q-L-Q-Q-E-L-A-V-V-L-Q-R-D-M-K-D-P-R-I-G-F-V-T-V-N-D-V-D-V-S-R-D-L-S-Y-A-K-V-F-V-T-F-F-E-E-D-K-D-V-V-Q-E-K-L-N-A-L-I-A-A-A-P-Y-I-R-T-L-V-A-G-R-M-K-L-R-V-M-P-E-I-R-F-V-Y-D-S-S-L-V-E-G-M-R-M-S-N-L-V-S-Q-V-I-N-S-D-K-A-K-Q-Q-Q-F-G-S-V-D-D-D-V-I-E-N-D-I-E-E-S-D-D-T-E-G-K-V


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-A-T-L-E-S-R-L-A-D-M-L-K-V-P-V-E-A-L-G-F-Q-L-W-G-I-E-Y-V-Q-A-G-K-H-S-I-L-R-V-F-I-D-G-E-N-G-I-N-I-E-D-C-A-N-V-S-R-Q-V-S-A-V-L-D-V-E-D-P-I-S-T-E-Y-T-L-E-V-S-S-P-G-V-D-R-P-L-F-T-A-E-Q-Y-A-A-Y-V-G-E-D-V-K-L-Q-L-T-M-P-V-A-G-S-R-N-L-K-G-A-I-T-Q-V-D-G-Q-M-L-S-V-N-V-N-G-K-E-L-V-V-A-L-D-N-I-R-K-G-N-I-I-A-K-F


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-S-E-I-K-L-I-V-G-L-A-N-P-G-A-E-Y-V-Q-T-R-H-N-A-G-A-W-Y-V-E-E-L-A-R-I-C-G-V-S-L-V-A-D-S-K-Y-F-G-L-T-A-R-A-V-L-H-G-K-D-V-R-L-L-I-P-T-T-Y-M-N-L-S-G-K-A-V-G-A-L-A-N-F-F-R-I-T-P-E-E-I-L-V-A-H-D-E-L-D-M-P-P-G-V-A-K-F-K-L-G-G-G-H-G-G-H-N-G-L-K-D-I-I-A-K-L-A-N-D-K-N-F-Y-R-L-R-I-G-I-G-H-P-G-D-K-N-K-V-S-G-Y-V-L-G-K-A-P-A-K-E-Q-E-L-I-N-A-A-V-D-E-A-V-R-S-T-E-I-L-F-K-E-D-M-V-K-A-M-T-R-L-H-S-F-K-A-E


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-S-L-D-L-A-L-D-V-Q-Y-A-T-T-S-D-Y-L-P-S-E-E-Q-L-A-L-W-V-K-T-A-I-G-N-S-M-K-Q-A-E-L-T-I-R-I-V-D-A-R-E-S-Q-M-L-N-G-T-Y-R-G-K-D-K-P-T-N-V-L-S-F-P-F-E-A-P-P-E-I-E-L-P-L-L-G-D-L-V-I-C-A-S-V-V-E-N-E-A-R-E-Q-D-K-T-L-E-A-H-W-A-H-M-V-V-H-G-C-L-H-L-L-G-Y-D-H-I-E-D-E-E-A-E-E-M-E-S-L-E-T-Q-L-I-E-S-L-G-F-T-D-P-Y-K-E-Q


### FUNCTION Specifically methylates the pseudouridine at position 1915  in 23S rRNA ### SEQUENCE -M-K-L-Q-L-I-A-V-G-T-R-M-P-D-W-V-T-R-G-F-E-E-Y-Q-R-R-F-P-R-D-M-A-L-E-L-I-E-I-P-A-G-K-R-G-K-N-A-D-I-V-R-I-L-Q-K-E-G-E-Q-M-L-A-A-I-P-K-G-N-H-I-V-T-L-D-L-P-G-K-N-W-T-T-P-E-L-A-S-A-M-N-K-W-Q-L-D-G-R-D-V-S-L-L-V-G-G-P-E-G-L-A-P-A-C-K-E-A-A-H-Q-S-W-C-L-S-A-L-T-L-P-H-P-L-V-R-I-V-V-A-E-S-L-Y-R-A-W-S-V-N-T-N-H-P-Y-H-R-E


### FUNCTION Involved in the synthesis of autoinducer 2 ### SEQUENCE -M-P-L-L-D-S-F-T-V-D-H-T-R-M-N-A-P-A-V-R-V-A-K-H-M-T-T-P-K-G-D-A-I-T-V-F-D-L-R-F-C-A-P-N-K-D-I-L-S-E-R-G-I-H-T-L-E-H-L-F-A-G-F-M-R-D-H-L-N-G-D-D-V-E-I-I-D-I-S-P-M-G-C-R-T-G-F-Y-M-S-L-I-G-V-P-T-E-R-Q-V-A-D-A-W-L-A-S-M-E-D-V-L-K-V-V-E-Q-S-E-I-P-E-L-N-E-Y-Q-C-G-T-Y-E-M-H-S-L-E-Q-A-Q-D-I-A-R-N-I-I-A-A-G-V-S-V-N-R-N-D-D-L-K-L-S-D-E-I-L-G-K-L


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-S-N-I-P-T-E-L-K-Y-A-S-S-H-E-W-I-R-K-E-E-D-G-S-Y-T-V-G-I-T-E-H-A-Q-E-L-L-G-D-M-V-F-V-E-L-P-E-V-G-D-T-V-T-A-G-D-D-C-A-V-A-E-S-V-K-A-A-S-D-I-Y-A-P-I-S-G-E-V-I-A-V-N-E-A-L-E-D-S-P-E-L-V-N-S-D-A-Y-G-E-G-W-F-F-R-V-M-P-S-D-E-S-E-V-D-A-L-L-D-A-E-G-Y-Q-A-V-I-D-E-E


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-Q-T-T-K-N-Q-D-D-L-V-R-I-F-K-A-I-L-K-E-E-R-F-G-S-Q-S-E-I-V-T-A-L-Q-A-E-G-F-T-N-I-N-Q-S-K-V-S-R-M-L-S-K-F-G-A-V-R-T-R-N-A-K-Q-E-M-V-Y-C-L-P-A-E-L-G-V-P-T-A-G-S-P-L-K-N-L-V-L-D-V-D-H-N-Q-A-M-I-V-V-R-T-S-P-G-A-A-Q-L-I-A-R-L-L-D-S-I-G-K-P-E-G-I-L-G-T-I-A-G-D-D-T-I-F-I-C-P-S-S-I-Q-D-I-A-D-T-L-E-T-I-K-S-L-F-N-Y-A-E


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-K-G-Q-S-L-Q-D-P-F-L-N-A-L-R-R-E-R-V-P-V-S-I-Y-L-V-N-G-I-K-L-Q-G-Q-V-E-S-F-D-Q-F-V-I-L-L-K-N-T-V-S-Q-M-V-Y-K-H-A-I-S-T-V-V-P-A-R-P-F-N-V-A-G-H-Q-N-A-Q-G-G-Y-G-A-Q-D-D-M-P-S-G-E


### FUNCTION 3'-to-5' exoribonuclease specific for small oligoribonucleotides ### SEQUENCE -M-A-A-D-A-N-N-L-I-W-I-D-L-E-M-T-G-L-E-P-D-V-D-R-V-I-E-I-A-T-L-V-T-D-Q-E-L-N-I-I-G-Q-G-P-V-I-A-I-H-Q-S-D-E-V-L-A-A-M-D-D-W-N-Q-K-H-H-G-E-S-G-L-I-E-R-V-R-A-S-Q-V-N-E-A-E-A-V-A-Q-T-I-A-F-L-A-Q-Y-V-P-K-G-V-S-P-M-C-G-N-S-V-G-Q-D-R-R-F-L-N-R-Y-M-R-E-L-E-D-Y-F-H-Y-R-N-L-D-V-S-T-V-K-E-L-V-K-R-W-S-P-E-T-M-A-G-F-K-K-Q-N-T-H-Q-A-L-Q-D-I-Q-E-S-I-A-E-L-Q-Y-Y-R-S-K-V-F-K-I


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-S-L-I-Q-E-F-K-A-F-A-S-R-G-N-V-I-D-M-A-V-G-I-I-I-G-A-A-F-G-K-I-V-S-S-F-V-A-D-I-I-M-P-P-I-G-I-I-L-G-G-V-N-F-S-D-L-S-V-V-L-L-A-A-Q-G-D-A-P-A-V-V-I-A-Y-G-K-F-I-Q-T-V-I-D-F-T-I-I-A-F-A-I-F-M-G-L-K-A-I-N-S-L-K-R-K-Q-E-E-A-P-P-A-S-P-A-P-T-K-D-Q-E-L-L-S-E-I-R-D-L-L-K-A-Q-Q-E-K


### FUNCTION Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase ### SEQUENCE -M-P-L-T-V-S-C-P-I-C-K-T-P-V-E-W-G-P-Q-S-K-F-K-P-F-C-S-E-R-C-K-M-I-D-L-G-D-W-A-S-E-K-H-A-I-P-V-K-S-E-F-D-L-D-A-L-D-E-L-G-Y-D-E-D-S-F-F-K-E


### FUNCTION Activates ribosomal RNA transcription Plays a direct role in upstream activation of rRNA promoters ### SEQUENCE -M-F-D-Q-T-T-N-T-E-V-H-Q-L-T-V-G-K-I-E-T-A-N-G-T-I-K-P-Q-L-L-R-D-A-V-K-R-A-V-T-N-F-F-A-Q-L-D-G-Q-E-A-Q-E-V-Y-E-M-V-L-S-E-V-E-A-P-L-L-D-I-I-M-Q-H-T-R-G-N-Q-T-R-A-A-N-M-L-G-I-N-R-G-T-L-R-K-K-L-K-K-Y-G-M-N


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-A-R-V-T-V-E-D-A-V-E-Q-I-G-N-R-F-D-M-I-L-V-A-A-R-R-A-R-Q-I-A-V-Q-G-K-D-P-M-V-E-E-M-N-D-K-P-T-V-I-A-L-R-E-I-E-L-G-L-V-N-A-H-T-L-D-A-D-E-R-Q-T-V-R-E-R-E-A-A-E-I-A-A-V-A-A-I-A-E-G-R-S-L


### FUNCTION Non-essential, abundant cell division factor that is required for proper Z-ring formation It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle Its recruitment to the Z-ring requires functional FtsA or ZipA ### SEQUENCE -M-S-L-E-L-L-S-K-L-E-T-K-I-Q-A-T-L-E-T-I-E-L-L-K-M-E-L-E-E-E-K-Q-K-T-S-T-L-S-E-Q-N-N-Q-L-I-E-Q-N-Q-Q-L-Q-Q-E-L-T-S-W-N-E-K-V-T-G-L-V-G-L-L-N-S-E-I


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-N-I-P-D-Q-K-H-T-V-I-A-L-T-A-I-F-G-I-G-R-T-R-A-R-A-I-C-A-A-T-S-I-A-E-T-A-K-I-K-E-L-S-E-A-Q-I-D-T-L-R-E-E-V-A-K-Y-L-V-E-G-D-L-R-R-E-I-S-M-N-I-K-R-L-M-D-L-G-C-Y-R-G-L-R-H-R-R-S-L-P-L-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-R-K-P-I-K-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-N-T-L-S-P-A-A-G-A-K-H-A-P-K-R-V-G-R-G-M-G-S-G-L-G-K-T-A-G-R-G-H-K-G-Q-K-S-R-S-G-G-G-V-R-P-G-F-E-G-G-Q-M-P-L-K-I-R-L-P-K-F-G-F-T-S-R-R-A-M-V-T-A-E-V-R-V-L-E-L-A-K-V-N-G-D-V-I-D-L-N-A-L-K-D-A-N-V-I-T-R-N-I-Q-F-A-K-I-V-L-S-G-T-I-E-R-P-V-T-V-K-G-L-K-V-T-K-G-A-R-A-A-I-E-A-A-G-G-K-I-E-E


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-D-K-K-T-S-R-L-R-R-A-I-R-A-R-K-K-I-Q-E-L-G-V-N-R-L-V-V-H-R-T-P-R-H-I-Y-A-Q-V-I-N-P-E-A-Q-V-V-A-A-A-S-T-V-E-K-A-V-K-E-Q-L-K-S-T-G-N-V-D-A-A-K-A-V-G-K-F-V-A-E-R-A-I-E-K-G-V-T-N-V-A-F-D-R-S-G-F-K-Y-H-G-R-V-A-A-L-A-D-A-A-R-E-A-G-L-Q-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-V-A-K-A-P-V-S-I-P-A-G-V-E-V-T-L-N-E-Q-T-L-T-V-K-G-A-K-G-S-L-T-R-V-I-N-N-A-V-N-V-V-I-E-N-G-V-I-K-F-L-P-V-E-G-A-V-G-A-W-A-Q-A-G-T-T-R-A-L-V-N-N-M-V-V-G-V-S-Q-G-F-E-R-K-L-K-L-V-G-V-G-Y-R-A-K-L-V-G-A-D-I-D-L-T-L-G-F-S-H-P-L-V-H-K-L-P-A-G-V-T-A-E-C-P-S-Q-T-D-I-V-L-R-G-V-D-K-Q-L-I-G-Q-V-A-A-E-I-R-G-Y-R-P-P-E-P-Y-K-G-K-G-V-R-Y-D-D-E-E-V-R-R-K-E-A-K-K-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-Q-D-P-I-A-D-M-L-T-R-I-R-N-G-Q-A-A-N-K-V-S-V-K-M-P-S-A-K-L-K-V-A-I-A-K-L-L-K-E-E-G-Y-I-A-D-Y-A-V-A-D-E-A-K-P-E-L-E-I-T-L-K-Y-F-Q-G-Q-P-V-V-E-T-I-Q-R-V-S-R-P-G-L-R-I-Y-K-G-K-N-E-L-P-K-V-M-G-G-L-G-V-A-I-V-S-T-S-K-G-L-M-T-D-R-A-A-R-L-A-G-M-G-G-E-V-I-C-Y-V-A


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-S-M-K-A-R-E-A-K-R-A-Q-L-V-A-K-F-A-E-K-R-A-A-L-K-V-I-I-A-S-P-A-S-S-D-E-D-R-W-D-A-V-L-K-L-Q-A-L-P-R-D-S-S-A-S-R-Q-R-N-R-C-N-Q-T-G-R-P-H-G-F-L-R-K-F-G-L-S-R-I-K-L-R-E-A-T-M-R-G-E-V-P-G-L-R-K-A-S-W