### FUNCTION Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein  and RNA polymerase recruitment Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes ### SEQUENCE -M-S-R-K-N-K-A-L-L-E-I-A-K-D-I-G-G-D-E-A-V-E-I-V-K-A-L-E-K-K-G-E-A-T-D-E-E-L-A-E-I-T-G-I-R-V-N-T-V-R-K-I-L-Y-A-L-Y-D-E-K-L-A-D-F-K-R-I-K-D-E-E-T-G-W-Y-Y-Y-Y-W-H-L-E-T-K-R-L-P-E-I-I-R-A-R-K-L-R-E-L-E-R-L-K-K-M-L-Q-E-E-T-S-E-V-Y-Y-H-C-G-N-P-E-H-P-K-L-T-F-D-E-A-F-E-Y-G-F-T-C-P-I-C-G-E-I-L-Q-E-Y-D-N-S-A-V-I-E-E-L-K-K-R-I-E-E-L-E-I-E-L-G-L-R-P-S-P-K-K-E-K-K-K-T-R-A-K-A-K-R-K-T-R-K-K


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-R-V-R-G-R-A-W-K-Y-G-D-N-I-D-T-D-V-I-I-P-A-R-Y-L-N-T-S-D-P-K-E-L-A-K-H-V-L-E-D-L-D-P-E-F-R-S-K-M-K-P-G-D-I-I-V-A-G-E-N-F-G-C-G-S-S-R-E-H-A-P-L-A-I-K-A-A-G-V-S-C-V-I-A-K-S-F-A-R-I-F-Y-R-N-A-I-N-I-G-L-P-I-L-E-A-P-Q-A-V-D-R-I-E-T-G-D-E-L-E-V-D-F-S-S-G-E-I-R-N-L-T-K-G-E-V-Y-R-A-N-P-F-P-D-F-I-M-E-I-I-K-A-G-G-L-V-E-W-A-K-R-R-L-K-G


### FUNCTION Putative transcriptional regulator ### SEQUENCE -M-K-T-F-L-T-E-Q-Q-I-K-V-L-V-L-R-A-K-G-L-K-Q-S-E-I-A-R-I-L-K-T-T-R-A-N-V-S-I-L-E-K-R-A-L-E-K-I-E-K-A-R-N-T-L-L-L-W-E-Q-I-N-S-K-V-S-V-S-V-K-A-G-E-D-I-F-T-I-P-D-R-L-F-K-E-A-D-K-A-G-V-K-V-P-Y-S-T-A-E-I-I-A-F-L-V-E-H-A-P-I-E-D-R-L-A-K-R-D-F-V-I-F-L-D-S-K-N-R-L-R-I-S-E-C-L-I-N-F-V-E-E-G-I-G-N-D


### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-R-F-F-V-S-G-M-P-G-V-G-K-T-T-L-A-K-R-I-A-D-E-I-R-R-E-G-Y-K-V-G-G-I-I-T-Q-E-I-R-T-G-P-K-R-S-G-F-R-V-I-A-L-D-T-G-E-I-G-R-L-A-Y-V-G-Q-G-Y-P-R-V-G-R-Y-V-V-D-I-E-G-F-D-R-V-A-I-P-A-I-S-R-A-L-R-D-A-D-I-I-I-I-D-E-I-G-P-M-E-F-K-S-N-E-F-L-K-A-L-G-L-V-L-K-S-E-K-P-L-L-A-T-V-H-R-K-L-V-D-R-Y-R-P-L-G-R-Y-Y-W-L-T-P-E-N-R-N-E-V-F-A-E-I-L-M-E-I-R-K-V-L-G-R-N-E-N-A-G-N-K-A


### FUNCTION Broad-specificity nucleoside monophosphate  kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates ### SEQUENCE -M-L-I-A-I-T-G-T-P-G-V-G-K-T-T-I-A-K-L-L-A-E-K-L-G-Y-E-Y-V-N-L-R-D-F-A-L-E-K-G-C-G-R-E-V-D-G-E-V-E-V-E-I-D-E-L-A-Y-F-V-E-K-E-L-K-D-R-N-V-V-L-D-G-H-L-S-H-L-M-P-V-D-L-V-V-V-L-R-A-H-P-R-I-I-G-E-R-L-R-E-R-G-Y-S-K-E-K-I-G-E-N-V-E-A-E-L-V-D-A-I-L-I-E-A-I-D-E-H-E-N-V-I-E-V-D-T-T-N-K-T-P-E-E-I-V-E-E-I-I-G-L-I-K-S-G-V-K-R-R-V-G-I-V-D-W-S-E-V-Y-D-E-I-I-P-Y-L-R-L-G-G-E


### FUNCTION General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation ### SEQUENCE -M-V-D-T-N-N-V-K-L-R-I-E-N-I-V-A-S-V-D-L-F-A-Q-L-D-L-E-K-V-L-D-I-C-P-N-S-K-Y-N-P-E-E-F-P-G-I-I-C-R-F-D-D-P-K-V-A-L-L-I-F-S-S-G-K-L-V-V-T-G-A-K-S-I-H-D-I-E-R-A-V-A-K-L-I-E-K-L-K-G-I-G-V-K-F-K-R-A-P-L-I-D-I-Q-N-M-V-F-S-G-D-I-G-R-E-F-N-L-D-N-V-A-L-T-L-P-N-C-E-Y-E-P-E-Q-F-P-G-V-I-Y-R-V-K-D-P-R-A-V-I-L-L-F-S-S-G-K-I-V-C-S-G-A-K-S-E-A-D-A-W-E-A-V-R-K-L-L-R-E-L-E-K-Y-G-L-I-E-E-E-E-E-E-L


### FUNCTION Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor  to the flavin N5 and C6 atoms of FMN ### SEQUENCE -M-R-V-V-V-A-I-T-G-A-S-G-T-I-Y-G-I-K-L-Y-E-T-L-R-D-L-G-H-E-V-I-L-L-A-S-K-T-G-I-K-V-A-K-Y-E-T-G-I-E-V-K-P-D-F-S-E-D-E-L-F-A-P-I-A-S-G-S-Y-P-F-D-A-M-V-I-A-P-C-S-M-K-T-L-S-A-I-A-N-G-F-S-N-N-L-I-T-R-A-A-D-V-A-L-K-E-R-R-K-L-V-L-L-I-R-E-T-P-L-N-L-I-H-I-Q-N-M-L-K-I-T-Q-A-G-G-I-I-M-P-A-S-P-A-F-Y-H-K-P-G-T-I-D-D-M-I-K-F-I-I-G-K-I-L-D-V-L-G-I-N-H-N-L-Y-K-R-W-G-M-D-Y-N-D


### FUNCTION S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 ### SEQUENCE -M-R-F-T-E-N-F-E-R-A-K-K-E-A-L-I-S-L-E-I-A-L-R-R-G-E-V-D-E-D-I-I-P-L-L-K-K-I-N-E-K-P-N-Y-F-T-T-S-S-C-S-G-R-I-S-I-M-E-M-P-D-F-G-D-K-V-N-A-K-W-L-G-K-W-H-R-E-V-S-L-D-E-V-L-E-A-I-R-K-H-R-E-G-Q-L-W-L-L-V-R-S-P-I-L-H-V-G-A-R-T-L-E-D-G-I-K-L-L-N-L-G-V-S-C-G-F-K-Y-S-N-I-K-S-I-S-D-R-K-L-I-V-E-I-R-S-T-E-R-L-D-A-L-L-G-E-N-G-E-I-L-V-S-D-D-Y-M-R-K-L-V-E-I-A-N-A-Q-V-R-R-F-K-R-K-L-K-R-F-E-E-R-I-E-E-L


### FUNCTION Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide ### SEQUENCE -M-L-K-D-T-I-K-S-G-D-W-K-G-E-K-H-V-P-V-I-E-Y-E-K-E-G-D-L-V-K-V-E-V-S-V-G-K-E-I-P-H-P-N-T-P-E-H-H-I-A-W-I-E-L-Y-F-H-P-E-D-G-Q-F-P-I-L-V-G-R-V-A-F-T-S-H-D-D-P-L-T-E-P-R-A-V-F-F-F-K-T-K-K-K-G-K-L-Y-A-L-S-Y-C-N-I-H-G-L-W-E-N-E-V-Q-L-E


### FUNCTION Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule ### SEQUENCE -M-A-K-W-R-C-K-I-C-G-Y-I-Y-D-E-D-E-G-D-P-D-N-G-I-S-P-G-T-K-F-E-D-L-P-D-D-W-V-C-P-L-C-G-A-P-K-S-E-F-E-R-I-E


### FUNCTION Involved in ribosome biogenesis ### SEQUENCE -M-R-F-R-I-R-K-C-P-K-C-G-R-Y-T-L-K-E-T-C-P-V-C-G-E-K-T-K-V-A-H-P-P-R-F-S-P-E-D-P-Y-G-E-Y-R-R-R-L-K-R-E-L-L-G-I-G-R-K-E-K


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-I-E-V-G-E-Y-K-V-K-E-G-L-Y-Y-T-K-E-H-E-W-A-Q-V-L-E-D-G-T-V-L-V-G-I-T-D-Y-A-Q-K-E-L-G-D-I-A-Y-V-E-L-P-E-V-G-K-E-V-K-K-G-E-V-L-C-E-V-E-S-V-K-A-V-S-E-V-Y-A-P-V-S-G-E-V-I-E-V-N-E-E-L-S-D-S-P-E-K-I-N-E-D-P-Y-G-A-W-I-A-K-I-K-P-N-N-L-E-E-E-L-K-E-L-M-D-A-E-K-Y-A-E-F-L-K-S-L


### FUNCTION May be involved in maturation of the 30S ribosomal subunit ### SEQUENCE -M-A-T-V-Y-D-V-P-G-D-L-L-V-E-R-V-A-Q-R-L-K-E-I-P-E-I-K-P-P-E-W-A-P-F-V-K-T-G-R-H-K-E-R-L-P-E-Q-E-D-W-W-Y-Y-R-V-A-S-I-L-R-R-V-Y-L-D-G-P-V-G-I-E-R-L-R-T-Y-Y-G-G-R-K-N-R-G-H-A-P-E-R-F-Y-K-A-G-G-S-I-I-R-K-A-L-Q-Q-L-E-A-A-G-F-V-E-K-V-P-G-K-G-R-V-I-T-P-K-G-R-S-F-L-D-K-I-A-T-E-L-K-K-E-L-E-E-I-I-P-E-L-K-K-Y


### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-K-L-K-T-L-P-P-T-L-R-D-K-N-R-Y-I-A-F-E-I-I-S-D-D-E-F-T-K-D-E-V-K-S-L-I-W-E-A-S-L-R-V-L-G-E-L-G-T-A-L-A-K-P-W-F-I-K-Y-D-P-K-T-K-T-G-I-V-R-C-D-R-E-Y-V-E-H-L-R-F-A-L-M-L-A-T-D-F-N-G-K-R-L-I-I-R-T-L-G-V-S-G-T-I-K-R-L-K-K-K-F-L-S-Q-Y-G-W-K


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-Q-K-A-R-I-K-L-A-S-T-N-V-R-S-L-E-E-V-A-N-Q-I-K-Q-I-A-E-R-T-G-V-R-M-S-G-P-I-P-L-P-T-K-R-I-R-I-V-T-R-K-S-P-D-G-E-G-S-A-T-F-D-R-W-E-L-R-I-H-K-R-L-I-D-I-E-A-D-E-R-A-M-R-Q-I-M-R-I-R-V-P-E-D-V-T-I-E-I-E-L-I-S


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-N-L-K-T-T-L-L-L-I-I-G-G-G-L-G-A-L-A-R-Y-Y-I-S-G-I-L-P-V-Y-K-D-F-P-L-G-T-L-L-V-N-S-I-A-S-F-I-L-G-Y-L-Y-G-L-L-F-F-G-F-E-V-S-S-E-W-R-I-F-L-G-T-G-F-C-G-G-L-S-T-F-S-T-F-S-Y-E-T-F-S-L-L-R-E-G-E-Y-L-L-A-F-M-N-V-V-A-N-V-L-V-T-I-T-L-V-F-L-G-F-I-L-A-R-R


### FUNCTION DNA-binding protein involved in the repression of transcription of a large number of genes, thereby arresting growth, in response to environmental changes ### SEQUENCE -M-R-V-S-L-D-E-I-D-R-R-I-I-K-I-L-Q-K-D-G-K-A-P-L-R-E-I-S-K-I-T-G-L-A-E-S-T-I-H-E-R-I-K-K-L-R-E-S-G-V-I-R-K-F-T-A-I-V-N-P-E-A-L-G-Y-S-M-L-A-F-I-L-I-K-V-K-A-G-K-Y-A-E-V-A-S-N-L-V-K-Y-E-E-I-M-E-V-Y-E-T-T-G-D-Y-D-M-V-V-K-I-R-T-K-N-S-E-E-L-N-S-F-L-D-V-I-G-S-I-P-G-V-E-G-T-H-T-M-I-V-L-K-T-H-K-E-T-T-E-L-P-I-K


### FUNCTION Contacts the emerging nascent chain on the ribosome ### SEQUENCE -M-M-P-M-N-P-K-Q-L-K-K-L-M-K-Q-L-D-M-K-Q-L-D-G-V-K-E-V-I-I-K-L-E-N-K-E-I-V-I-K-E-P-V-V-T-V-I-R-A-M-G-E-K-M-Y-Q-I-A-G-G-T-E-E-E-R-V-V-L-K-I-S-E-E-D-I-K-L-V-M-E-Q-A-G-V-D-Y-E-T-A-K-K-A-L-E-E-A-G-G-D-L-A-E-A-I-L-R-L-T-D-Q


### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently -methyltransferase PAB1947 against aggregation and increases its specificity ### SEQUENCE -M-K-R-W-E-H-Y-E-H-T-A-D-I-G-I-R-G-Y-G-D-S-L-E-E-A-F-E-A-V-A-I-A-L-F-D-V-I-V-N-V-N-K-V-E-K-K-E-V-R-E-V-E-V-E-G-E-D-L-E-S-L-L-Y-N-F-L-E-E-L-L-V-I-H-D-I-E-G-L-V-F-R-D-F-E-V-K-I-E-K-T-E-K-G-Y-K-L-K-A-K-A-Y-G-E-K-L-D-P-E-K-H-E-P-K-E-E-V-K-A-I-T-Y-H-D-M-K-I-E-K-L-P-D-G-R-W-M-A-Q-L-V-P-D-I


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-F-K-F-K-Q-V-I-V-V-R-K-D-L-K-L-S-K-G-K-L-A-V-Q-V-A-H-G-A-V-T-A-A-F-K-A-Y-K-E-K-R-E-W-F-E-K-W-F-H-E-G-Q-K-K-V-V-V-K-V-E-S-L-D-E-L-F-K-L-K-A-E-A-E-K-L-N-L-P-T-A-L-I-Q-D-A-G-L-T-E-I-P-P-G-T-I-T-V-L-A-I-G-P-G-P-S-E-I-I-D-K-V-T-G-H-L-K-L-L


### FUNCTION Seems to be required for maximal rate of protein biosynthesis Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA ### SEQUENCE -M-P-K-K-E-R-K-V-E-G-D-E-V-I-R-V-P-L-P-E-G-N-Q-L-F-G-V-V-E-Q-A-L-G-A-G-W-M-D-V-R-C-E-D-G-K-I-R-R-C-R-I-P-G-K-L-R-R-R-V-W-I-R-V-G-D-L-V-I-V-Q-P-W-P-V-Q-S-D-K-R-G-D-I-V-Y-R-Y-T-Q-T-Q-V-D-W-L-L-R-K-G-K-I-T-Q-E-F-L-T-G-G-S-L-L-V-E


### FUNCTION Involved in the maturation of  hydrogenases Required for nickel insertion into the metal center of the hydrogenase ### SEQUENCE -M-H-E-W-A-L-A-D-A-I-V-R-T-A-L-D-Y-A-Q-K-E-N-A-S-K-I-L-A-I-K-V-V-L-G-E-L-Q-D-V-N-A-E-V-V-E-F-A-M-K-E-L-L-R-G-T-I-G-E-G-A-E-I-I-F-E-E-E-E-A-V-F-R-C-R-N-C-G-H-E-W-K-L-K-E-V-K-D-K-L-D-E-R-I-R-E-D-I-H-F-I-P-E-V-V-H-A-F-I-S-C-P-N-C-G-S-H-D-F-E-V-V-K-G-R-G-V-Y-I-A-G-I-K-I-E-K-E-E-G-E


### FUNCTION DNA-binding protein that negatively regulates its own transcription Interferes with RNA polymerase  recruitment by inhibiting the association of RNAP with the TBP-TFB promoter complex ### SEQUENCE -M-V-D-E-R-D-K-I-I-L-D-I-L-S-K-D-A-R-T-P-F-T-E-I-A-K-I-L-G-I-S-E-T-A-V-R-K-R-V-K-A-L-E-E-K-G-I-I-E-G-Y-T-I-K-I-N-P-K-K-L-G-Y-S-L-V-T-I-T-G-V-D-T-R-P-E-K-L-F-E-V-A-E-K-L-K-E-F-E-F-V-R-E-L-Y-L-S-S-G-D-H-M-I-M-A-V-I-W-A-K-D-G-E-D-L-A-D-I-I-S-N-K-I-G-K-I-D-G-V-T-K-V-C-P-A-I-I-L-E-R-L-K


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-R-I-I-N-A-E-G-L-I-L-G-R-L-A-S-R-V-A-K-M-L-L-E-G-E-E-V-V-I-V-N-A-E-K-A-V-I-T-G-N-R-E-V-I-F-S-K-Y-K-Q-R-T-G-L-R-T-L-T-N-P-R-R-G-P-F-Y-P-K-R-S-D-E-I-V-R-R-T-I-R-G-M-L-P-W-K-T-D-R-G-R-K-A-F-K-R-L-K-V-Y-V-G-I-P-K-E-F-K-D-K-Q-L-E-T-I-V-E-A-H-V-S-R-L-S-R-P-K-Y-V-T-V-G-E-V-A-K-F-L-G-G-K-F


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-D-F-R-H-I-V-R-V-A-G-V-D-L-D-G-N-K-Q-L-R-W-A-L-T-A-I-K-G-V-G-I-N-F-A-T-M-V-C-R-V-A-G-L-D-P-F-M-K-A-G-Y-L-T-D-E-Q-V-K-K-I-E-E-I-L-Q-D-P-V-A-H-G-I-P-R-W-A-V-N-R-P-K-D-Y-E-T-G-R-D-L-H-L-I-T-A-K-L-D-M-A-I-R-E-D-I-M-R-L-R-R-I-R-A-Y-R-G-I-R-H-E-L-G-L-P-V-R-G-Q-R-T-R-S-N-F-R-R-G-Q-T-V-G-V-S-R-K-K-K


### FUNCTION Binds and compact DNA ### SEQUENCE -M-A-E-L-P-I-A-P-V-D-R-L-I-R-K-A-G-A-Q-R-V-S-E-K-A-A-K-L-L-A-E-H-L-E-E-K-A-L-E-I-A-K-K-A-V-D-L-A-K-H-A-G-R-K-T-V-K-V-E-D-I-K-L-A-I-R-S


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-I-T-T-G-R-V-W-K-F-W-D-N-V-S-T-D-E-I-T-P-G-R-Y-N-L-T-K-D-P-Q-E-L-A-R-I-A-F-I-E-V-R-P-E-F-A-E-K-V-R-R-G-D-V-V-V-G-G-K-N-F-G-I-G-S-S-R-E-S-A-A-L-A-L-K-A-A-G-V-S-G-I-I-A-K-S-F-G-R-I-F-Y-R-N-A-V-N-L-G-I-P-L-L-I-G-D-T-D-E-L-E-D-G-D-V-I-T-V-N-W-E-T-G-E-V-R-K-N-G-Q-T-L-Q-F-E-P-L-P-G-F-L-L-E-I-V-R-E-G-G-I-L-E-F-I-R-R-R-G-D-L-C-I-G


### FUNCTION Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP ### SEQUENCE -M-S-K-F-V-I-W-T-S-E-L-D-S-R-L-S-K-K-Y-G-R-V-V-P-R-N-L-A-V-E-R-P-S-I-E-E-I-E-E-A-A-K-S-L-G-F-K-V-L-Q-V-E-R-E-K-L-N-P-K-L-S-G-I-D-E-D-L-R-T-Y-G-R-I-I-I-E-S-P-Y-G-K-A-K-T-L-K-I-I-A-Q-K-I-R-E-L-R-R-R-R


### FUNCTION Binds double-stranded DNA tightly but without sequence specificity It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture However, it does not significantly compact DNA Binds rRNA and mRNA in vivo May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes ### SEQUENCE -M-T-E-E-H-V-V-Y-I-G-K-K-P-V-M-N-Y-V-L-A-V-I-T-Q-F-H-E-G-A-K-E-V-S-I-K-A-R-G-R-A-I-S-R-A-V-D-V-A-E-I-V-R-N-R-F-L-K-D-D-V-D-V-K-E-I-K-I-G-T-E-E-L-P-T-A-D-G-R-T-T-N-T-S-T-I-E-I-V-L-A-R-K-A


### FUNCTION Probable zinc metalloprotease whose natural substrate is unknown ### SEQUENCE -M-M-G-M-I-I-I-V-P-I-G-E-V-P-G-D-V-L-A-F-L-Q-N-S-L-S-G-F-Y-A-K-Y-G-I-E-V-R-L-V-G-G-L-S-L-S-K-F-Q-H-A-F-D-F-E-R-R-Q-F-L-A-R-Y-F-L-P-V-L-S-Y-I-R-K-D-F-N-A-K-A-A-L-G-V-V-N-V-D-I-Y-E-L-G-L-N-F-I-F-G-L-A-H-P-G-L-R-V-A-I-I-S-L-Y-R-L-Y-P-E-F-Y-G-N-P-P-D-R-K-L-L-K-E-R-A-L-K-E-A-M-H-E-L-G-H-V-F-G-L-E-H-C-P-N-P-K-C-V-M-H-F-S-N-S-I-I-D-T-D-I-K-S-W-M-Y-C-E-K-C-L-R-K-L-E-K-N-L-T-R-S-Y-V


### FUNCTION Binds to 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome ### SEQUENCE -M-D-P-Y-K-V-I-I-R-P-V-I-T-D-K-A-I-S-L-I-E-K-E-N-K-L-T-F-I-V-D-R-R-A-T-K-Q-D-I-K-R-A-I-E-E-I-F-N-V-K-V-E-K-V-N-T-L-I-T-P-K-G-E-K-K-A-Y-V-K-L-K-P-E-Y-S-A-S-E-I-A-A-R-L-G-L-F


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-K-E-F-R-Y-R-G-Y-T-L-E-Q-L-M-N-M-S-L-E-E-L-A-K-L-L-P-A-R-Q-R-R-S-L-K-R-G-L-T-P-E-Q-K-K-L-L-R-K-I-R-L-A-K-K-G-K-Y-N-K-P-I-R-T-H-C-R-D-M-I-V-L-P-E-M-V-G-L-T-I-Y-V-H-N-G-K-E-F-V-P-V-E-I-K-P-E-M-I-G-H-Y-L-G-E-F-A-P-T-R-K-R-V-Q-H-G-A-P-G-I-G-A-T-R-S-S-M-F-V-A-V-K


### FUNCTION This protein binds specifically to 23S rRNA It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome ### SEQUENCE -M-G-R-R-F-D-Y-S-F-Q-N-F-D-P-E-R-M-A-R-A-S-G-R-D-L-R-I-S-P-K-L-A-V-E-V-C-R-E-L-R-G-M-M-L-N-D-A-L-R-Y-L-D-D-V-I-A-L-R-R-P-V-P-L-K-R-Y-N-D-S-Q-G-H-K-P-G-K-G-F-G-P-G-R-Y-P-V-K-V-A-K-A-I-K-K-V-L-L-N-A-Q-N-N-A-K-Q-K-G-L-D-P-D-K-L-R-I-I-H-I-A-A-H-R-G-P-V-L-R-G-W-Y-P-R-A-F-G-R-P-T-P-F-N-E-Q-T-T-H-I-E-V-V-V-E-E-V-R-R


### FUNCTION Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends ### SEQUENCE -M-R-R-N-G-K-E-R-K-D-R-T-S-G-G-S-Q-R-P-Y-Q-E-I-V-G-R-T-W-I-F-R-G-S-H-R-G-R-V-T-K-R-N-I-I-W-H-E-L-I-G-L-K-V-R-V-V-N-S-M-H-P-G-F-V-G-I-E-G-Y-V-V-D-E-T-R-N-M-L-V-I-V-G-D-K-V-W-K-V-P-K-D-V-C-I-F-E-F-E-T-E-D-G-A-K-I-K-I-P-G-E-R-L-V-G-R-P-E-M-R-L-K-K-R-W-R-K-W


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-V-R-D-I-G-L-R-I-Q-P-P-A-E-K-C-D-D-P-K-C-P-W-H-G-H-L-K-I-H-G-R-V-F-E-G-I-V-V-S-D-K-P-R-K-T-V-T-V-E-R-Q-Y-Y-H-Y-L-K-K-Y-E-R-Y-E-L-R-R-S-R-I-H-A-H-N-P-P-C-I-N-A-K-V-G-D-R-V-L-I-A-E-T-R-P-L-S-K-T-K-H-F-V-V-V-A-V-L-E-R-A-E-E-R-R


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-A-K-K-G-A-G-A-T-R-G-I-T-P-V-R-P-T-R-A-I-P-V-G-A-Y-L-T-V-A-D-N-S-G-A-K-V-I-Q-V-I-G-V-V-E-Y-H-G-T-R-R-R-L-A-S-A-G-V-G-D-M-V-V-A-T-V-K-K-G-R-P-D-M-R-H-Q-V-V-R-A-V-I-I-R-Q-R-K-E-Y-R-R-L-D-G-M-R-I-K-F-E-D-N-A-A-V-I-V-T-P-E-G-V-P-R-G-T-E-I-R-G-P-V-A-R-E-A-A-E-R-W-V-R-I-G-S-I-A-S-I-I-V


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-R-L-N-S-K-Q-P-R-K-Q-R-K-F-L-Y-N-A-P-L-H-L-R-Q-K-M-M-A-A-P-L-S-K-E-L-R-E-K-Y-K-I-R-N-L-P-V-R-V-G-D-K-V-R-I-M-R-G-D-F-K-G-H-E-G-K-V-V-E-V-D-L-K-R-Y-R-I-Y-V-E-G-A-T-L-R-K-T-N-G-T-E-V-F-Y-P-I-H-P-S-N-V-M-I-I-E-L-N-L-D-D-E-R-R-K-K-I-I-E-R-R-A-G


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-I-T-I-P-N-R-E-E-I-L-A-D-W-E-A-H-P-M-R-K-P-R-I-E-K-V-T-I-N-I-G-V-G-E-S-G-E-R-L-T-K-A-E-I-M-L-E-R-L-T-G-Q-K-P-I-R-R-K-A-K-K-T-N-R-D-F-G-I-R-R-G-E-P-I-A-V-K-V-T-L-R-G-P-K-A-Y-E-M-L-K-R-L-L-A-A-V-D-N-R-L-K-A-S-S-F-D-E-H-G-N-V-C-F-G-I-D-E-H-I-N-I-P-G-V-E-Y-D-P-E-I-G-I-F-G-M-D-V-C-V-T-L-E-R-P-G-F-R-V-A-R-R-K-R-K-R-A-K-I-P-T-R-H-K-L-T-K-E-E-G-M-V-Y-M-M-E-E-F-G-V-E-I-V-E-E-E-G


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-T-L-L-D-P-L-A-N-A-L-S-H-I-T-N-S-E-R-V-G-K-R-E-V-Y-I-K-P-A-S-K-L-I-G-E-V-L-R-V-M-Q-K-Y-G-Y-I-G-E-F-E-F-I-D-D-G-R-A-G-V-Y-R-V-Q-L-L-G-K-I-N-K-A-G-A-I-K-P-R-F-P-V-K-A-R-D-Y-E-R-W-E-K-R-F-L-P-A-F-E-F-G-I-L-I-V-S-T-S-Q-G-V-M-S-H-K-E-A-R-E-K-G-I-G-G-R-L-I-A-Y-V-Y


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-P-V-D-A-W-V-R-E-E-I-E-I-P-E-G-V-E-V-S-V-Q-G-N-T-V-K-V-K-G-P-K-G-E-V-E-R-E-L-F-W-P-G-V-K-I-F-V-E-G-G-K-V-V-I-Y-K-D-F-P-R-R-K-D-V-A-I-V-R-T-F-K-A-H-I-N-N-M-I-K-G-V-T-E-G-F-T-Y-K-L-K-V-V-Y-S-H-F-P-I-T-V-K-V-Q-G-D-E-V-I-I-E-N-F-L-G-E-K-A-P-R-R-A-K-I-L-P-G-V-T-V-K-V-K-G-Q-E-I-I-V-E-G-I-D-K-E-A-V-G-Q-T-A-A-N-I-E-Q-A-T-R-I-T-K-W-D-R-R-V-F-Q-D-G-I-Y-I-V-E-K-A-G-K-P-I-T-F


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-T-L-K-M-Q-R-R-V-A-A-E-L-L-K-C-G-E-N-R-I-W-I-D-P-E-R-V-D-D-V-A-S-A-I-T-R-E-D-I-R-R-L-I-K-E-G-V-I-K-K-K-P-V-K-G-Q-S-R-Y-R-A-R-I-R-H-E-Q-K-K-K-G-R-H-R-G-P-G-S-R-K-G-K-K-T-A-R-M-G-K-K-E-L-W-I-K-T-I-R-A-L-R-K-E-L-R-K-L-K-E-Q-K-K-I-D-R-R-T-Y-R-M-L-Y-I-R-A-K-G-G-Q-F-K-S-K-H-Q-L-Y-M-F-L-E-E-H-N-L-L-K-K-R


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-I-R-R-R-K-K-V-R-K-L-R-G-S-H-T-H-G-W-G-C-K-K-K-H-R-G-G-G-S-K-G-G-R-G-M-A-G-T-G-K-R-N-K-S-K-W-T-W-T-I-K-Y-A-P-D-H-L-G-K-R-G-F-S-R-P-P-E-V-Q-R-E-V-R-T-V-T-L-K-S-I-D-E-N-L-D-E-L-L-Q-K-G-I-A-Y-E-E-E-G-K-I-I-V-D-T-T-Q-F-A-D-K-V-L-G-T-G-K-I-T-K-P-L-V-I-K-A-R-A-F-S-S-K-A-E-E-K-I-K-A-A-G-G-E-A-V-L-V


### FUNCTION Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate ### SEQUENCE -M-G-K-A-Q-S-V-R-F-K-V-S-K-L-M-A-Y-I-L-R-H-D-P-W-S-F-N-L-Q-P-D-E-E-G-F-V-D-L-E-E-F-V-N-A-I-R-R-V-Y-P-W-V-T-K-E-F-I-L-D-I-V-E-R-D-E-K-E-R-Y-E-V-K-E-G-K-I-R-A-R-Y-G-H-S-Y-P-V-I-L-D-H-K-E-D-K-E-S-K-T-L-Y-H-G-T-I-R-E-N-L-E-G-I-M-R-E-G-I-K-P-M-K-R-Q-F-V-H-L-S-L-N-Y-E-D-A-Y-N-T-G-R-R-H-G-S-N-V-V-V-L-M-I-D-A-D-C-L-R-K-K-G-F-K-I-L-K-A-G-K-K-V-R-I-V-K-Y-V-P-V-D-C-I-V-G-E-L


### FUNCTION Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA ### SEQUENCE -M-S-D-F-N-I-V-G-V-I-K-V-M-P-S-D-P-E-V-N-L-D-E-L-E-E-K-L-K-A-V-I-P-E-K-Y-G-L-A-K-V-E-R-E-P-I-A-F-G-L-V-A-L-K-F-Y-V-L-G-K-D-E-E-G-Y-S-F-D-E-V-A-E-K-F-K-E-V-E-N-V-E-S-A-E-V-E-T-V-S-R-I


### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-P-E-L-Q-E-R-I-R-N-F-L-K-E-S-K-R-V-F-L-V-T-R-K-P-G-W-E-E-Y-K-K-A-A-K-I-T-G-L-G-I-I-L-I-G-L-I-G-M-L-I-R-I-M-G-I-L-V-L-G-G


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -M-K-K-Q-V-V-E-V-L-V-E-G-G-K-A-T-P-G-P-P-L-G-P-A-I-G-P-L-G-L-N-V-K-Q-V-V-D-K-I-N-E-A-T-K-E-F-A-G-M-Q-V-P-V-K-I-I-V-D-P-V-T-K-Q-F-E-I-E-V-G-V-P-P-T-S-Q-L-I-K-K-E-L-G-L-E-K-G-S-G-E-P-K-H-N-I-V-G-N-L-T-M-E-Q-V-I-K-I-A-K-M-K-R-N-Q-M-L-A-L-T-L-K-A-A-A-K-E-V-I-G-T-A-L-S-M-G-V-T-V-E-G-K-D-P-R-E-V-Q-R-E-I-D-E-G-V-Y-D-E-L-F-E-K-A-E-K-E


### FUNCTION Essential subunit of the Sec protein translocation channel SecYEG Clamps together the 2 halves of SecY May contact the channel plug during translocation ### SEQUENCE -M-D-V-K-Y-D-L-N-S-Y-V-R-V-L-K-L-A-S-T-P-S-W-Q-E-F-S-Q-I-S-K-I-A-G-A-G-I-F-L-V-G-L-L-G-F-I-I-F-A-V-M-S-F-L-P-G-G-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-S-S-E-E-Q-E-D-V-D-E-D-I-Q-Y-F-V-R-I-G-Q-T-D-L-D-G-T-K-T-V-E-R-A-L-A-E-L-G-G-V-G-R-R-V-A-R-I-V-A-D-E-A-G-V-D-R-T-A-T-M-G-G-L-E-D-D-A-I-E-S-V-T-D-A-V-D-S-F-T-E-H-A-P-A-W-L-A-N-R-Q-N-D-F-Y-T-G-E-N-Q-H-I-T-G-T-D-V-E-L-T-R-D-Q-D-I-N-R-M-R-M-I-R-S-Y-K-G-I-R-H-E-R-G-Q-K-V-R-G-Q-R-T-K-S-T-G-R-T-E-G-T-I-G-V-N-V-E-A-I-K-E-E-Q-A-E-D-D-A-A-D-G-G-E-E


### FUNCTION Molecular chaperone Seems to fulfill an ATP-independent, HSP70-like function in protein folding May protect essential factors of cell proliferation during heat shock No role in calpain activation ### SEQUENCE -M-S-T-I-V-R-K-L-I-S-T-A-N-A-A-K-P-V-A-P-Y-N-Q-A-V-V-A-D-R-T-V-Y-V-S-G-C-L-G-L-D-K-D-T-M-K-L-V-P-G-G-P-T-E-Q-A-Q-K-A-L-E-N-L-E-A-V-L-K-A-A-D-S-G-V-D-K-V-I-K-N-T-V-F-L-K-D-L-N-D-F-G-A-V-N-E-V-Y-K-R-V-F-N-K-D-F-P-A-R-S-C-F-Q-V-A-K-L-P-M-D-A-L-V-E-I-E-C-I-A-L-T-G-S-V-E-T-K-T-V-Q


### FUNCTION Involved in mitochondria homeostasis ### SEQUENCE -M-K-R-L-K-A-Y-L-K-D-G-I-N-V-A-A-V-M-C-L-G-D-T-I-S-Q-F-F-F-D-K-K-S-L-D-E-W-D-A-G-R-T-L-R-F-G-I-V-G-L-V-F-V-G-P-T-L-R-R-W-Y-H-F-L-E-S-R-V-P-K-T-Y-S-P-M-R-R-G-V-T-K-M-L-V-D-Q-T-L-F-A-P-P-F-T-M-A-M-S-F-L-V-P-L-S-N-G-E-P-I-D-R-I-R-Q-R-I-L-D-S-Y-L-S-I-L-V-R-N-Y-M-L-W-P-A-A-Q-M-L-N-F-R-F-V-P-L-G-Y-Q-V-L-Y-A-Q-F-I-A-L-V-W-N-C-Y-L-S-M-I-L-N-S


### FUNCTION Required for ribosome biogenesis Part of a complex which catalyzes pseudouridylation of rRNA This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 Pseudouridine ### SEQUENCE -M-Y-L-M-Y-T-I-N-E-N-G-D-R-V-Y-T-L-K-K-R-T-E-D-G-R-P-T-L-S-A-H-P-A-R-F-S-P-E-D-K-Y-S-R-Q-R-L-T-I-K-K-R-F-G-L-L-L-T-Q-K-P-E-P-I-Y


### FUNCTION Necessary for protein translocation in the endoplasmic reticulum ### SEQUENCE -M-D-K-V-V-K-F-A-E-P-G-R-A-F-A-K-D-S-I-R-L-V-K-R-C-T-K-P-D-R-K-E-F-Q-K-I-A-I-A-T-A-V-G-F-A-I-M-G-F-I-G-F-F-V-K-L-I-H-I-P-I-N-N-I-I-V-G-S


### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-L-K-L-W-L-I-C-I-L-T-V-S-V-V-S-I-Q-S-L-S-L-L-E-E-T-N-Y-V-S-D-C-L-A-S-N-N-I-S-Q-A-E-F-Q-E-L-I-D-R-N-S-S-E-E-D-D-L-E-N-T-D-R-R-Y-K-C-F-I-H-C-L-A-E-K-G-N-L-L-D-T-N-G-Y-L-D-V-D-K-I-D-Q-I-E-P-V-S-D-E-L-R-E-I-L-Y-D-C-K-K-I-Y-D-E-E-E-D-H-C-E-Y-A-F-K-M-V-T-C-L-T-E-S-F-E-Q-S-D-E-V-T-E-A-G-K-N-T-N-K-L-N-E


### FUNCTION Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid ### SEQUENCE -M-L-D-Q-L-T-L-C-L-L-L-N-F-L-C-A-N-V-L-A-N-T-S-V-F-N-P-C-V-S-Q-N-E-L-S-E-Y-E-A-H-Q-V-M-E-N-W-P-V-P-P-I-D-R-A-Y-K-C-F-L-T-C-V-L-L-D-L-G-L-I-D-E-R-G-N-V-Q-I-D-K-Y-M-K-S-G-V-V-D-W-Q-W-V-A-I-E-L-V-T-C-R-I-E-F-S-D-E-R-D-L-C-E-L-S-Y-G-I-F-N-C-F-K-D-V-K-L-A-A-E-K-Y-V-S-I-S-N-A-K


### FUNCTION Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB ### SEQUENCE -M-E-V-E-F-S-R-E-N-F-L-L-P-E-M-K-Y-E-Y-L-D-H-T-A-D-V-Q-I-H-G-W-G-S-S-L-K-E-A-F-E-Q-C-G-V-A-M-F-G-Y-M-T-E-L-D-Y-V-S-V-E-Q-C-F-E-I-E-A-H-G-D-D-L-E-S-L-L-F-H-F-L-D-E-L-L-F-L-F-S-A-E-P-Y-L-V-C-K-K-L-E-I-T-K-F-D-V-E-N-F-E-I-S-C-H-C-Y-G-E-P-F-E-L-G-K-H-P-Q-G-T-E-V-K-A-I-T-Y-S-A-M-Q-I-I-Q-D-V-E-A-S-N-Y-E-V-F-V-I-I-D-I


### FUNCTION This protein binds cations of several transition elements Thought to be involved in metal ion homeostasis ### SEQUENCE -M-V-C-K-G-C-G-T-N-C-K-C-Q-D-T-K-C-G-D-N-C-A-C-N-Q-D-C-K-C-V-C-K-N-G-P-K-D-Q-C-C-K-S-K


### FUNCTION Antiviral effector protein expressed downstream of Sting and Rel  signaling in response to viral infection ### SEQUENCE -M-D-S-A-I-S-E-I-I-N-A-L-A-I-L-A-D-D-K-N-I-Q-L-T-I-K-E-A-G-K-G-A-A-I-C-A-G-A-A-L-I-G-G-L-L-L-G-P-R-G-L-A-L-G-G-A-I-G-G-L-T-A-Y-G-L-T-E-G-N-F-K-S-L-S-E-V-I-L-N-D-L-T-E-S-Q-R-R-E-L-E-Q-H-V-I-R-A-I-S-E-V-R-N-V-R-V-R-D-V-A-R-L-I-L-N-N-R-H-V-Q-E-V-A-L-E-A-V-K-S-Y-I-T-D-R-M-G-M-T-I-V-D


### FUNCTION DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs Pol II is the central component of the basal RNA polymerase II transcription machinery It is composed of mobile elements that move relative to each other RPB11 is part of the core element with the central large cleft ### SEQUENCE -M-N-A-P-P-T-F-E-S-F-L-L-Y-E-G-E-K-K-I-I-K-E-L-D-T-K-V-T-N-A-A-I-F-T-I-N-K-E-D-H-T-L-G-N-M-I-R-N-Q-L-L-K-D-P-N-V-L-F-A-G-Y-K-V-P-H-P-L-E-H-K-F-V-I-R-I-Q-T-T-A-D-Y-S-P-Q-E-A-F-M-N-A-I-T-D-L-L-A-E-L-S-L-F-E-E-R-F-K-D-A-I-K-E-K-K-E-G-G-D


### FUNCTION Probably has thioredoxin reductase-like oxidoreductase activity ### SEQUENCE -M-E-R-L-T-G-R-N-V-A-L-L-V-L-C-L-C-A-G-Y-A-L-V-F-A-E-G-E-K-E-I-P-V-T-K-F-G-Q-N-I-A-P-T-M-T-F-L-Y-C-Y-S-C-G-Y-R-K-A-F-E-D-Y-V-G-L-L-G-E-K-Y-P-Q-I-Q-V-N-G-G-N-Y-D-P-P-G-L-N-Y-Y-L-S-K-M-I-F-A-L-K-I-I-I-I-V-S-V-V-S-A-V-S-P-F-T-F-L-G-L-N-T-P-S-W-W-S-H-M-Q-A-N-K-I-Y-A-C-M-M-I-F-F-L-G-N-M-L-E-A-Q-L-I-S-S-G-A-F-E-I-T-L-N-D-V-P-V-W-S-K-L-Q-T-G-R-F-P-S-P-E-V-L-F-Q-I-I-D-N-H-L-Q-F-T-E-K-V-Q-E-N-P-D-F-V-K


### FUNCTION Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane ### SEQUENCE -M-A-E-Y-G-R-E-P-C-P-F-R-I-V-E-D-C-G-G-A-F-A-M-G-A-L-G-G-G-A-F-Q-A-I-K-G-F-R-N-A-P-S-G-L-G-Y-R-L-S-G-G-L-A-A-V-R-A-R-S-G-L-V-G-G-N-F-A-V-W-G-A-T-F-S-A-I-D-C-S-L-V-Y-F-R-K-K-E-D-P-W-N-A-I-I-S-G-A-T-T-G-G-I-L-A-A-R-T-G-L-T-S-M-L-S-S-A-L-V-G-G-A-L-L-A-L-I-E-G-V-G-I-V-V-S-H-Y-S-A-D-S-Y-R-Q-V-S-P-V-E-R-Q-Q-R-Y-K-Q-E-L-L-R-Q-Q-K-G-V-S-P-L-A-A-T-Y-G-E-I-D-S-S-A-L


### FUNCTION Subunit of the V1 complex of vacuolar ### SEQUENCE -M-S-T-P-T-H-N-L-P-R-T-R-V-S-A-F-C-W-V-A-L-E-R-S-T-R-I-E-R-P-T-S-W-S-W-K-E-L-S-H-Y-S-L-I-V-F-H-C-I-P-D-T-T-P-K-Q-I-E-E-C-F-K-K-F-L-R-R-P-D-I-V-I-I-L-I-N-Q-V-Y-A-D-M-I-R-P-T-V-D-A-H-N-L-A-V-P-T-V-L-E-I-P-S-K-Q-H-P-Y-D-S-S-R-D-S-I-L-K-R-A-Q-R-V-I-T-P-P-E-R-H-Y


### FUNCTION Required for the assembly of the V0 complex of the vacuolar ATPase  in the endoplasmic reticulum ### SEQUENCE -M-S-T-K-N-K-K-A-A-G-G-N-G-V-A-P-K-Q-T-R-Q-Q-S-H-D-S-Q-D-Y-S-S-F-K-T-V-L-F-Y-C-M-L-I-V-F-L-P-V-L-T-F-F-V-L-K-G-F-V-L-D-Q-F-L-D-I-S-E-V-K-V-N-I-A-S-A-V-G-A-V-V-A-L-H-I-A-L-G-L-Y-I-Y-R-A-Y-F-G-A-P-G-S-K-G-S-K-T-D


### FUNCTION Subunit of the oligosaccharyl transferase  All subunits are required for a maximal enzyme activity ### SEQUENCE -M-I-E-T-L-Y-N-L-P-F-H-I-L-V-P-P-N-I-K-V-R-R-F-S-I-P-M-P-S-P-M-A-V-F-S-V-I-L-F-S-Y-F-L-V-T-G-G-I-I-Y-D-V-I-V-E-P-P-S-L-G-A-T-V-D-E-H-G-H-S-R-P-V-A-F-M-P-Y-R-V-N-G-Q-Y-I-M-E-G-L-A-S-S-F-L-F-T-V-G-G-L-G-F-I-I-M-D-Q-T-H-T-P-G-K-T-N-L-N-R-L-L-L-T-A-M-G-F-I-F-I-L-V-S-F-F-T-T-W-L-F-M-R-M-K-L-P-S-Y-L-Q-P


### FUNCTION Mitochondrial membrane ATP synthase  is coupled via a rotary mechanism of the central stalk subunits to proton translocation ATP5MK is a minor subunit of the mitochondrial membrane ATP synthase required for dimerization of the ATP synthase complex and as such regulates ATP synthesis in the mitochondria ### SEQUENCE -M-S-D-H-F-N-F-N-E-A-F-N-S-Q-T-M-R-G-R-A-N-V-A-K-A-T-W-A-S-L-G-L-V-Y-V-L-V-K-M-H-R-R-N-T-K-R-R-E-T-K-L-Y-C-K-G-C-Q-Q-A-M-L-H-G


### FUNCTION Binds specifically to cytosolic chaperonin ### SEQUENCE -M-A-A-K-V-A-S-G-T-N-K-V-F-Q-N-H-D-D-V-H-I-S-F-E-D-Q-Q-R-I-N-R-F-A-K-H-N-A-R-M-D-D-F-K-A-E-L-E-T-K-R-N-E-L-K-S-L-E-E-A-L-E-E-I-E-L-F-D-E-D-E-D-I-P-F-L-V-G-E-V-F-L-S-H-K-L-E-K-T-Q-D-M-L-K-E-T-K-E-Q-V-L-K-E-I-A-G-V-E-A-K-A-K-V-I-K-A-E-M-D-E-L-K-A-H-L-Y-Q-R-F-G-S-N-I-S-L-E-A-E-D


### FUNCTION Component of the signal recognition particle ### SEQUENCE -M-V-F-V-K-N-W-D-D-F-E-I-A-V-E-N-M-Y-L-A-N-P-Q-N-C-R-L-T-M-K-Y-A-H-S-K-G-H-I-L-L-K-M-T-D-N-V-K-C-V-Q-Y-K-A-E-N-M-P-D-L-R-K-I-E-K-I-T-S-N-L-V-G-H-M-A-S-K-E


### FUNCTION Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner May act as a co-chaperone that stimulate the ATP-dependent activity ### SEQUENCE -M-A-S-S-V-I-L-A-G-L-S-V-A-A-V-G-F-A-G-K-H-L-M-R-R-M-P-Q-M-T-T-K-F-N-E-A-L-K-N-L-P-K-Y-D-A-E-S-M-A-A-S-K-Y-Y-K-G-G-F-D-P-K-M-N-K-R-E-A-S-L-I-L-G-V-S-P-S-A-S-K-I-K-I-K-D-A-H-K-K-I-M-L-L-N-H-P-D-R-G-G-S-P-Y-L-A-A-K-I-N-E-A-K-D-F-L-D-K-A-K


### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-A-A-A-N-M-E-K-G-E-L-M-N-Q-V-K-Q-Q-I-A-L-A-N-A-Q-E-M-L-S-K-M-T-E-K-C-F-K-K-C-I-Q-K-P-G-K-S-L-D-S-T-E-Q-R-C-I-S-Q-C-M-D-R-F-M-D-A-W-N-L-V-S-R-T-Y-G-N-R-L-Q-R-E-Q-Y-R-T-M-E-S-L-E-M-T-S


### FUNCTION Binds specifically to cytosolic chaperonin ### SEQUENCE -M-D-K-K-S-A-A-L-Y-K-K-M-Q-A-E-I-E-S-Y-Q-N-L-Q-K-S-C-L-K-M-V-K-Q-R-A-V-L-E-S-Q-L-N-E-N-K-C-V-L-D-E-L-N-L-L-G-P-D-N-K-V-Y-K-L-F-G-P-V-L-V-K-Q-E-L-E-E-S-R-Q-N-V-G-K-R-I-E-Y-I-S-K-E-L-K-S-S-T-D-A-L-E-N-M-E-K-D-M-L-K-H-R-E-S-V-A-K-Y-Q-Q-Q-C-Q-V-A-A-A-M-Q


### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-A-K-T-P-E-N-I-A-I-D-Q-L-D-K-D-Q-I-K-T-F-S-D-F-L-M-S-Y-N-K-L-S-E-T-C-F-T-D-C-I-R-D-F-T-T-R-D-V-K-D-S-E-E-K-C-S-L-N-C-M-E-K-Y-L-K-M-N-Q-R-V-S-Q-R-F-Q-E-F-Q-V-I-A-H-E-N-A-L-A-M-A-Q-K-T-G-K-L


### FUNCTION Component of the signal peptidase complex ### SEQUENCE -M-G-K-K-D-E-K-S-Q-Q-G-E-E-L-V-K-V-N-K-W-D-G-S-A-V-K-H-A-L-D-D-A-V-K-T-C-L-L-G-D-R-P-Q-L-K-E-Q-F-G-L-V-N-T-R-L-A-L-C-A-L-A-V-S-V-A-I-M-A-H-A-W-D-F-T-H-P-F-P-E-S-R-P-V-L-L-F-S-V-L-A-Y-F-A-L-L-G-I-L-T-L-H-S-S-F-R-E-K-G-T-F-A-V-A-L-Q-K-D-K-E-R-E-R-L-W-E-A-S-S-D-M-R-K-Y-D-D-K-Y-L-L-T-L-S-V-R-D-T-K-N-G-K-R-R-E-Q-S-S-N-K-S-C-A-A-F-I-D-Q-N-G-I-V-L-D-N-L-V-A-N-E-V-N-R-L-F-N-A-L-A-A-D-K-K-N-A-S-S-L-S-S-N


### FUNCTION May be involved in iversification of muscle cell fates ### SEQUENCE -M-L-I-A-W-L-V-L-A-A-T-L-S-R-S-I-R-A-S-T-T-I-S-I-P-I-T-T-Q-D-I-I-A-G-D-V-F-F-E-I-L-S-P-S-E-L-E-Y-T-Y-R-L-R-P-A-K-D-F-G-S-A-F-S-E-R-L-E-G-V-P-L-V-I-T-D-P-P-G-A-C-Q-E-I-R-N-A-R-D-L-N-G-G-V-A-L-I-D-R-G-E-C-S-F-L-T-K-T-L-R-A-E-A-A-G-A-L-A-A-I-I-T-E-Y-N-P-S-S-P-E-F-E-H-Y-I-E-M-I-H-D-N-S-Q-Q-D-A-N-I-P-A-G-F-L-L-G-K-N-G-V-I-I-R-S-T-L-Q-R-L-K-R-V-H-A-L-I-N-I-P-V-N-L-T-F-T-P-P-S-K-I-N-H-P-P-W-L-G-W


### FUNCTION Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome ### SEQUENCE -M-G-M-V-S-K-R-K-K-M-H-Y-G-D-T-H-L-Q-R-R-W-R-V-R-N-R-R-R-D-L-D-Q-I-D-D-D-L-Q-T-R-S-G-E-L-I-N-Q-N-V-D-L-D-K-P-G-F-A-Q-F-Y-C-V-H-C-A-K-Y-F-I-D-D-T-A-M-Q-A-H-F-R-T-K-V-H-K-R-R-L-K-A-L-E-I-E-P-Y-S-I-E-E-A-E-R-A-A-G-R-G-S-F-V-K-P-K-K-R-A-M-E-T-Q-P-S-K-E-D-V-V-A-G-K-R-I-R-V-E-V-V-P-E-D-T-D-A-T-D-S-P-S-T-S-K-T-K-R-K-K-V-E-K-M-E-T


### FUNCTION TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation TFIIA in a complex with TBP mediates transcriptional activity ### SEQUENCE -M-N-Y-Q-H-Y-R-A-T-T-L-G-R-T-L-Q-D-T-L-D-E-M-M-E-R-G-D-I-T-K-K-I-A-N-L-V-L-L-R-Y-D-K-S-I-S-T-A-L-K-D-H-G-T-S-N-M-S-F-T-A-E-R-L-E-T-F-R-C-C-D-N-V-W-T-L-I-L-K-D-A-E-F-R-E-D-Q-H-S-L-K-V-D-V-V-K-I-V-A-C-L-G-T-D-N-G-N-E


### FUNCTION Required for the assembly of the ubiquinol-cytochrome c reductase complex  May be involved in cytochrome b translation and/or stability ### SEQUENCE -M-G-F-T-G-P-L-K-Y-N-K-W-K-I-K-I-A-A-L-R-M-Y-T-C-C-V-E-R-I-D-Y-D-E-F-F-E-K-C-S-L-P-D-T-L-N-S-W-F-L-V-T-Q-L-H-V-W-M-C-L-V-R-M-K-Q-E-G-R-A-G-K-Y-M-C-R-Y-I-V-H-S-M-W-E-D-V-E-Q-R-G-K-V-M-G-I-D-S-V-T-L-K-N-S-M-R-S-M-T-E-I-F-Y-A-A-I-F-G-Y-D-E-G-I-I-S-D-D-R-I-L-A-A-A-L-W-R-N-L-L-N-K-Q-C-D-D-P-R-K-L-E-L-L-V-E-Y-V-R-K-Q-V-Q-F-L-D-T-L-D-G-E-D-L-L-L-T-G-E-V-V-W-R-P-L-V-E-K-D-A-Q-S-I-L-K-P-S-T-P-T-Y-N-D-E-G-L


### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1  with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-N-Q-H-I-P-P-F-Y-K-T-C-A-A-G-K-N-L-C-Y-K-I-F-M-V-A-A-P-K-V-P-V-K-R-G-C-I-D-V-C-P-K-S-S-D-L-V-K-Y-V-C-C-N-T-D-R-C-N


### FUNCTION Shows cytolytic activity on many different cells by forming pore in lipid membranes In vivo, increases heart rate or kills the animal by cardiac arrest In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1  with moderate affinity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-K-C-N-K-L-V-P-L-F-Y-K-T-C-P-A-G-K-N-L-C-Y-K-M-F-M-V-S-N-L-T-V-P-V-K-R-G-C-I-D-V-C-P-K-S-S-L-L-V-K-Y-V-C-C-N-T-D-R-C-N


### FUNCTION Component of the small ribosomal subunit The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell Required for processing of pre-rRNA and maturation of 40S ribosomal subunits ### SEQUENCE -M-N-D-T-V-T-I-R-T-R-K-F-M-T-N-R-L-L-Q-R-K-Q-M-V-V-D-V-L-H-P-G-K-A-T-V-P-K-T-E-I-R-E-K-L-A-K-M-Y-K-T-T-P-D-V-V-F-V-F-G-F-R-T-Q-F-G-G-G-K-T-T-G-F-A-M-V-Y-D-S-L-D-Y-A-K-K-N-E-P-K-H-R-L-A-T-H-G-L-Y-E-K-K-K-T-S-R-K-Q-R-T-E-R-Q-N-R-M-K-K-V-R-S-I-K-K-A-S-V-G-A-A-G-K-K-N


### FUNCTION Has low cytotoxic activity ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-K-C-H-N-T-Q-L-P-F-I-Y-K-T-C-P-E-G-K-N-L-C-F-K-A-T-L-R-K-F-P-L-K-F-P-V-K-R-G-C-A-D-N-C-P-K-N-S-A-L-L-K-Y-V-C-C-S-T-D-K-C-N


### FUNCTION Antagonist of muscle and neuronal nicotinic acetylcholine receptors  with highest affinity for neuronal alpha-7/CHRNA7 nAChRs ### SEQUENCE -M-K-T-L-L-L-T-L-A-V-V-T-M-V-C-M-D-L-G-Y-T-T-I-C-Y-N-H-L-S-R-T-P-E-T-T-E-I-C-P-D-S-W-Y-F-C-Y-K-I-S-L-A-D-G-N-D-V-R-I-K-R-G-C-T-F-T-C-P-E-L-R-P-T-G-K-Y-V-Y-C-C-R-R-D-K-C-N-Q


### FUNCTION Postsynaptic neurotoxin that binds and inhibits neuronal nicotinic acetylcholine receptors  Is a selective, and slowly reversible antagonist of alpha-3/CHRNA3-containing and some alpha-4/CHRNA4-containing AChRs ### SEQUENCE -M-K-T-L-L-L-S-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-R-T-C-H-I-S-T-S-S-T-P-Q-T-C-P-K-G-Q-D-I-C-F-R-K-T-Q-C-D-K-F-C-S-I-R-G-A-V-I-E-Q-G-C-V-A-T-C-P-E-F-R-S-N-Y-R-S-L-L-C-C-R-T-D-N-C-N-P


### FUNCTION Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery ### SEQUENCE -M-A-A-Q-V-T-E-S-D-Q-I-K-Q-F-K-E-F-L-G-T-Y-N-K-L-T-E-N-C-F-M-D-C-V-K-D-F-T-T-R-E-V-K-P-E-E-T-T-C-S-E-S-C-L-Q-K-Y-L-K-M-T-Q-R-I-S-M-R-F-Q-E-Y-H-I-Q-Q-N-E-R-W-P-Q-K-P-D-Y


### FUNCTION Binds with low affinity to muscular ### SEQUENCE -M-K-T-L-L-L-T-L-V-V-V-T-I-V-C-L-D-L-G-Y-T-L-T-C-L-N-C-P-E-M-F-C-G-K-F-Q-T-C-R-N-G-E-K-I-C-F-K-M-L-Q-Q-R-R-P-F-S-L-R-Y-I-R-G-C-A-A-T-C-P-G-T-K-P-R-D-M-V-E-C-C-N-T-D-R-C-N-R


### FUNCTION Binds with high affinity to muscle nicotinic acetylcholine receptor  and hinders acetylcholine binding to the receptor, thereby impairing neuromuscular transmission Causes muscle paralysis, spasms and increased respiration ### SEQUENCE -M-K-T-L-L-L-T-L-V-M-V-T-I-M-C-L-D-L-G-Y-T-L-T-C-Y-K-G-Y-H-D-T-V-V-C-K-P-H-E-T-I-C-Y-E-Y-F-I-P-A-T-H-G-N-A-I-L-A-R-G-C-G-T-S-C-P-G-G-I-R-P-V-C-C-R-T-D-L-S-N-K


### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-A-Y-T-V-S-S-A-N-Q-L-V-Y-L-G-S-V-W-A-D-P-L-E-L-Q-N-L-C-T-S-A-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-S-D-V-W-K-T-I-P-T-A-T-V-R-F-P-A-T-G-F-K-V-F-R-Y-N-A-V-L-D-S-L-V-S-A-L-L-G-A-F-D-T-R-N-R-I-I-E-V-E-N-P-Q-N-P-T-T-A-E-T-L-D-A-T-K-R-V-D-D-A-T-V-A-I-R-A-S-I-S-N-L-M-N-E-L-I-R-G-T-G-M-Y-N-Q-A-L-F-E-M-A-S-G-F-T-W-A-T-I-P-Y-T


### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-S-I-T-S-P-S-Q-F-V-F-L-S-S-V-W-A-D-P-I-E-L-L-N-F-G-T-N-S-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-S-E-V-W-K-P-F-P-Q-S-T-V-R-F-P-G-D-V-Y-K-V-Y-R-Y-N-A-V-L-D-P-L-I-T-A-L-L-G-S-F-D-T-R-N-R-I-I-E-V-E-N-Q-Q-N-P-T-T-A-E-T-L-D-A-T-R-R-V-D-D-A-T-V-A-I-R-S-A-I-N-N-L-V-N-E-L-V-R-G-T-G-L-Y-N-Q-N-T-F-E-S-M-S-G-L-V-W-T-S-A-P-A-S


### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-A-Y-T-V-S-S-A-N-Q-L-V-Y-L-G-S-V-W-A-D-P-L-E-L-Q-N-L-C-T-S-A-L-G-N-Q-F-Q-T-Q-Q-A-R-T-T-V-Q-Q-Q-F-S-D-V-W-K-T-I-P-T-A-T-V-R-F-P-A-T-G-F-K-R-F-R-Y-N-A-V-L-D-S-L-V-S-A-L-L-G-A-F-D-T-R-N-R-I-I-E-V-E-N-P-Q-N-P-T-T-A-E-T-L-D-A-T-M-R-V-D-D-A-T-V-A-I-R-A-S-I-S-P-I-M-N-E-L-V-R-G-T-G-M-Y-N-Q-A-L-F-E-S-A-S-G-L-T-W-A-T-T-P


### FUNCTION Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA ### SEQUENCE -M-S-Y-N-I-T-S-S-N-Q-Y-Q-Y-F-A-A-M-W-A-E-P-Q-A-M-L-N-Q-C-V-S-A-L-S-Q-S-Y-Q-T-Q-A-A-R-D-T-V-R-Q-Q-F-S-N-L-L-S-A-I-V-T-P-N-Q-R-F-P-E-S-G-Y-R-V-Y-I-N-S-A-V-L-K-P-L-Y-E-A-L-M-K-S-F-D-T-R-N-R-I-I-E-T-E-E-E-S-R-P-S-A-S-E-V-A-N-A-T-Q-R-V-D-D-A-T-V-A-I-R-S-Q-I-Q-L-L-L-N-E-L-S-N-G-H-G-L-M-N-R-A-E-F-E-V-L-L-P-W-T-T-A-P-A-T


### FUNCTION May transport viral genome to neighboring plant cells directly through plasmosdesmata, without any budding The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier ### SEQUENCE -M-A-D-T-G-Y-Y-A-G-Y-Q-D-D-V-D-V-D-E-Q-K-R-H-Q-A-L-Y-L-I-G-I-I-L-L-V-T-V-C-L-T-V-L-W-V-C-I-M-L-A-C-Y-V-P-G-F-L-K-K-T-L-E-A-W-L-N-S-S-S-L-M-K-R-R-V-A-S-T-L-T-R-T-P-F-E-A-T-G-P-E-R-E-R-N-W-E-A-R-R-Q-S-T-T-V-N-P-A-S-Q-P-N-T-G-S-V-F


### FUNCTION Putative nuclear shuttle protein ### SEQUENCE -M-A-D-W-F-S-S-P-L-K-T-C-T-H-V-C-D-F-P-S-L-A-G-D-P-Q-Q-E-I-M-C-C-D-S-M-K-N-K-L-Q-D-S-R-K-V-L-L-V-S-C-S-V-S-F-N-G-S-F-Y-G-G-N-R-N-V-R-G-Q-L-Q-I-S-M-V-E-D-D-G-V-C-R-P-I-G-Y-V-P-I-G-G-Y-L-Y-H-N-D-Y-G-Y-Y-E-G-A-R-T-F-N-L-D-L-E-S-Q-Y-L-K-K-D-E-D-Y-N-R-K-F-L-V-S-V-F-N-E-N-G-L-D-S-Q-C-D-L-K-V-F-I-V-H-S-I-R-I-K-V


### FUNCTION Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly ### SEQUENCE -M-T-T-I-R-G-D-D-L-S-N-Q-I-T-Q-I-S-G-S-S-S-K-K-E-E-E-K-K-K-Q-Q-M-L-T-G-V-L-G-L-Q-P-T-M-A-N-H-P-V-L-G-V-F-L-P-K-Y-A-K-Q-N-G-G-N-V-D-K-T-A-F-R-L-D-L-I-R-M-L-A-L-H-R-L-N-T-K-T-G-S-D


### FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase , that is believed not to be involved in catalysis Complex I functions in the transfer of electrons from NADH to the respiratory chain The immediate electron acceptor for the enzyme is believed to be ubiquinone ### SEQUENCE -M-W-F-E-I-L-P-G-L-A-V-M-G-V-C-L-V-I-P-G-V-A-T-A-Y-I-H-K-Y-T-N-G-G-K-E-K-R-V-G-R-L-R-Y-Q-W-Y-L-M-E-R-D-R-R-V-S-G-V-N-R-Y-Y-V-S-R-G-L-E-N-I-D


### FUNCTION Regulates arginine biosynthesis genes ### SEQUENCE -M-K-I-S-K-K-R-R-Q-E-L-I-R-K-I-I-H-E-K-K-I-S-N-Q-F-Q-I-V-E-E-L-K-K-Y-G-I-K-A-V-Q-P-T-V-A-R-D-L-K-E-I-G-A-V-K-I-M-D-E-S-G-N-Y-V-Y-K-L-L-D-E-T-P-V-I-D-P-W-K-E-L-K-R-N-F-K-S-F-V-E-S-I-D-R-A-G-N-L-I-V-I-K-T-I-P-G-T-A-S-G-I-A-R-V-I-D-R-L-D-I-D-E-I-V-G-T-L-A-G-D-D-T-I-F-V-A-V-R-D-P-E-S-C-E-K-I-V-E-K-L-S-S-I-L


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-S-I-R-P-L-Y-D-K-V-V-V-K-R-I-E-A-Q-R-T-T-A-S-G-I-V-I-P-D-T-A-S-E-K-P-E-Q-G-E-V-I-A-T-G-N-G-R-R-L-Q-D-G-T-Q-V-P-L-E-V-K-V-G-D-Q-V-L-F-G-K-Y-A-G-Q-T-V-K-L-H-G-E-E-L-L-V-L-R-E-E-D-I-L-G-V-V-E-A-S-D-A-K-L-K-K-V-A


### FUNCTION Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule Could be involved in hydrogenase-linked redox processes ### SEQUENCE -M-S-E-Q-A-V-E-N-T-V-L-D-R-F-E-C-R-S-C-G-Y-V-Y-E-P-E-K-G-D-N-K-H-D-I-A-P-E-T-P-F-A-E-L-P-I-N-W-R-C-P-V-C-T-A-K-K-A-A-F-T-N-I-G-P-A-G-T-A-S-G-F-R-E-N-L-G-Y-G-L-G-V-N-K-L-T-P-A-Q-K-N-I-L-I-F-G-A-L-A-L-G-F-L-F-F-I-S-L-Y-G-L-Q


### FUNCTION Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase ### SEQUENCE -M-V-Q-R-G-S-K-V-R-I-L-R-P-E-S-Y-W-F-Q-D-V-G-T-V-A-S-V-D-Q-S-G-I-K-Y-P-V-I-V-R-F-E-K-V-N-Y-S-G-I-N-T-N-N-F-A-E-D-E-L-V-E-V-E-A-P-K-A-K-P-K-K


### FUNCTION Cytochrome bo ### SEQUENCE -M-A-N-A-H-D-T-H-H-E-G-N-H-G-S-V-K-S-Y-M-I-G-F-I-L-S-I-I-L-T-A-I-P-F-G-L-A-M-S-P-S-L-P-K-N-L-T-V-L-I-I-V-A-M-A-V-I-Q-V-V-V-H-L-V-Y-F-L-H-M-D-R-S-K-E-Q-R-N-N-V-W-T-F-L-F-T-T-L-V-I-A-L-L-V-G-L-S-L-W-I-M-F-S-I-H-F-E-M-L-A-K


### FUNCTION Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase ### SEQUENCE -M-A-R-Y-Q-C-P-D-C-Q-Y-V-Y-D-E-S-K-G-E-E-H-E-G-F-A-P-N-T-P-W-I-V-I-P-E-D-W-C-C-P-D-C-A-V-R-D-K-L-D-F-V-L-I-E-G-S-T-G-E-K-N-I-S-S-N-N-T-L-S-V-S-A-K-V-S-S-S-D-V-N-T-E-I-S-N-T-T-M-S-A-E-I-A-L-D-V-A-T-E-G-Q-H-L-N-G-R-K-P-R-V-T-N-L-Q-S-G-A-A-F-L-K-W-I-C-I-T-C-G-H-I-Y-D-E-A-L-G-D-E-V-E-G-F-A-P-G-T-R-F-E-D-I-P-N-D-W-C-C-P-D-C-G-A-T-K-E-D-Y-V-L-Y-Q-E-K-L-G


### FUNCTION Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase ### SEQUENCE -M-A-K-Y-Q-C-P-D-C-Q-Y-I-Y-D-E-C-K-G-E-P-H-E-G-F-Q-P-N-T-N-W-G-E-I-P-E-E-W-A-C-P-D-C-A-V-R-D-K-I-D-F-K-M-L-A-D-P-R-C-E-I-T-Q-L-K-Q-N-D-P-V-I-K-Q-D-N-N-I-I-E-D-T-L-S-E-P-S-I-L-S-A-E-L-E-F-T-A-E-K-I-S-I-T-D-E-R-E-N-T-P-D-N-K-V-E-R-R-S-Q-S-Q-A-V-R-R-S-S-V-K-K-I-K-N-N-K-R


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-T-L-K-E-L-Y-A-E-T-R-S-H-M-Q-K-S-L-E-V-L-E-H-N-L-A-G-L-R-T-G-R-A-N-P-A-L-L-L-H-L-K-V-E-Y-Y-G-A-H-V-P-L-N-Q-I-A-T-V-T-A-P-D-P-R-T-L-V-V-Q-S-W-D-Q-N-A-L-K-A-I-E-K-A-I-R-D-S-D-L-G-L-N-P-S-N-K-G-D-A-L-Y-I-N-I-P-P-L-T-E-E-R-R-K-D-L-V-R-A-V-R-Q-Y-A-E-E-G-R-V-A-I-R-N-I-R-R-E-A-L-D-K-L-K-K-L-A-K-E-L-H-L-S-E-D-E-T-K-R-A-E-A-E-I-Q-K-I-T-D-E-F-I-A-K-A-D-Q-L-A-E-K-K-E-Q-E-I-L-G


### FUNCTION Required for bacteriochlorophyll biosynthesis Directly involved in the assembly of both the B875 and B800-850 pigment-protein complexes ### SEQUENCE -M-T-D-Q-T-S-D-V-H-M-V-R-G-H-R-P-P-K-A-E-F-M-V-Y-F-T-I-I-F-I-A-A-L-P-L-A-F-I-A-S-F-L-A-M-V-R-Q-G-D-L-K-T-K-G-P-I-A-R-A-W-S-Q-A-R-I-I-T-P-M-I-F-S-A


### FUNCTION General  is transferred to the phosphoryl carrier protein HPr by enzyme I Phospho-HPr then transfers it to the PTS EIIA domain ### SEQUENCE -M-F-Q-N-Q-V-K-I-T-A-P-H-G-L-H-T-R-P-A-A-Q-F-V-K-E-A-K-K-F-T-S-E-I-S-I-I-Y-N-G-K-S-V-N-A-K-S-L-F-K-I-Q-T-L-G-L-I-Q-G-S-L-I-T-L-S-A-E-G-E-D-E-K-K-A-I-E-H-L-S-L-I-M-T-E-L-E


### FUNCTION Fluoride-specific ion channel Important for reducing fluoride concentration in the cell, thus reducing its toxicity ### SEQUENCE -M-I-E-L-D-Y-L-T-I-A-F-G-G-A-I-G-A-V-L-R-Y-L-V-S-R-T-I-N-S-L-L-P-F-S-Y-I-P-L-G-T-I-I-V-N-S-V-G-S-F-F-L-S-F-L-M-F-A-A-I-E-K-V-P-L-S-K-E-A-I-L-F-F-G-T-G-L-L-G-A-F-T-T-F-S-T-F-T-Y-E-T-L-S-L-I-E-E-S-P-A-R-G-V-A-Y-A-L-A-N-L-L-F-A-F-T-C-A-Y-F-G-M-I-L-G-R-G-K-V


### FUNCTION Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP May hydrolyze nucleoside diphosphates with lower efficiency ### SEQUENCE -M-K-I-L-I-T-G-R-P-G-V-G-K-T-T-L-I-K-K-L-S-R-L-L-Q-N-A-G-G-F-Y-T-E-E-M-R-E-G-E-K-R-I-G-F-K-I-I-T-L-D-G-E-E-G-I-L-A-R-T-D-L-P-S-P-Y-R-V-G-K-Y-Y-V-N-L-K-D-L-E-E-I-G-V-R-S-L-E-R-A-F-Q-E-K-D-L-I-I-V-D-E-I-G-K-M-E-L-L-S-R-K-F-R-E-V-V-E-K-I-F-D-S-E-K-D-V-I-A-T-I-K-K-S-S-D-P-F-V-E-K-I-K-N-R-N-D-V-V-I-F-E-L-N-E-K-N-R-N-S-L-L-N-E-I-L-S-V-L-K-F-N-R-G-E-K-Q


### FUNCTION Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin Binds to flagellin and participates in the assembly of the flagellum ### SEQUENCE -M-V-Y-K-T-K-L-G-E-I-E-I-S-D-E-S-I-F-T-F-E-K-G-I-P-G-F-E-H-L-R-K-F-A-L-V-F-P-Q-E-T-F-P-I-G-W-L-L-S-L-E-D-S-E-V-G-L-P-V-V-D-P-K-L-V-R-A-D-Y-D-P-A-V-P-S-E-D-L-E-E-I-E-A-E-N-Q-E-A-L-L-F-F-C-V-L-T-I-P-P-G-K-P-E-K-T-T-I-N-L-R-A-P-I-I-L-N-Q-K-K-K-K-G-I-Q-T-I-L-E-N-E-D-Y-Q-L-R-H-L-L-S-E-E-I-E-R-S-K-T-V-V


### FUNCTION The glycine cleavage system catalyzes the degradation of glycine The H protein shuttles the methylamine group of glycine from the P protein to the T protein ### SEQUENCE -M-K-M-K-K-Y-T-K-T-H-E-W-V-S-I-E-D-K-V-A-T-V-G-I-T-N-H-A-Q-E-Q-L-G-D-V-V-Y-V-D-L-P-E-V-G-R-E-V-K-K-G-E-V-V-A-S-I-E-S-V-K-A-A-A-D-V-Y-A-P-L-S-G-K-I-V-E-V-N-E-K-L-D-T-E-P-E-L-I-N-K-D-P-E-G-E-G-W-L-F-K-M-E-I-S-D-E-G-E-L-E-D-L-L-D-E-Q-A-Y-Q-E-F-C-A-Q-E


### FUNCTION A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW ### SEQUENCE -M-L-V-L-T-R-R-V-G-E-K-I-V-I-G-E-D-I-V-I-T-V-L-K-I-E-G-N-S-V-K-I-G-I-E-A-P-K-H-V-K-I-L-R-E-E-L-Y-E-E-L-K-S-E-N-I-K-A-S-E-V-S-K-D-D-L-K-G-V-L-R-N-D-K-G-Y-K-G-P-S-A-S-S


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-I-R-G-R-V-W-K-F-G-D-N-I-S-T-D-H-I-A-P-G-R-Y-F-H-L-R-N-N-L-E-E-L-A-K-H-V-L-E-D-A-M-E-D-F-A-K-K-V-Q-K-G-D-I-I-V-A-G-K-N-F-G-L-G-S-S-R-E-H-A-A-R-I-I-K-I-A-G-V-S-C-I-V-A-K-S-F-A-R-I-F-Y-R-N-A-I-N-V-G-L-P-V-I-E-L-K-E-V-D-E-I-N-Q-G-D-E-L-E-I-D-L-E-N-G-V-L-K-N-L-T-T-G-K-E-Y-R-F-T-P-I-P-K-F-L-L-E-I-L-K-E-D-G-I-V-N-Y-L-K-K-H-G-S-F-P-K-V


### FUNCTION Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide ### SEQUENCE -M-P-R-V-G-I-I-M-G-S-D-S-D-L-P-V-M-K-Q-A-A-E-I-L-E-E-F-G-I-D-Y-E-I-T-I-V-S-A-H-R-T-P-D-R-M-F-E-Y-A-K-N-A-E-E-R-G-I-E-V-I-I-A-G-A-G-G-A-A-H-L-P-G-M-V-A-S-I-T-H-L-P-V-I-G-V-P-V-K-T-S-T-L-N-G-L-D-S-L-F-S-I-V-Q-M-P-G-G-V-P-V-A-T-V-A-I-N-N-A-K-N-A-G-I-L-A-A-S-I-L-G-I-K-Y-P-E-I-A-R-K-V-K-E-Y-K-E-R-M-K-R-E-V-L-E-K-A-Q-R-L-E-Q-I-G-Y-K-E-Y-L-N-Q-K-E


### FUNCTION RNA chaperone that binds small regulatory RNA  and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations Also binds with high specificity to tRNAs ### SEQUENCE -M-A-L-A-E-K-F-N-L-Q-D-R-F-L-N-H-L-R-V-N-K-I-E-V-K-V-Y-L-V-N-G-F-Q-T-K-G-F-I-R-S-F-D-S-Y-T-V-L-L-E-S-G-N-Q-Q-S-L-I-Y-K-H-A-I-S-T-I-I-P-S-S-Y-V-M-L-M-P-K-K-Q-E-T-A-Q-E-A-E-T-S-E-N-E-G-S


### FUNCTION Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate ### SEQUENCE -M-V-V-K-I-K-G-K-V-F-V-F-G-D-N-V-N-T-D-E-I-I-P-A-R-Y-L-N-T-S-D-P-Q-E-L-A-K-Y-C-M-E-D-A-R-P-G-F-G-R-R-D-D-I-K-G-S-I-I-V-A-G-E-N-F-G-C-G-S-S-R-E-H-A-P-V-A-I-K-A-A-G-I-S-C-V-I-A-K-S-F-A-R-I-F-F-R-N-A-I-N-I-G-L-P-I-V-E-L-K-E-A-D-E-F-E-E-G-D-I-A-E-V-D-L-E-N-G-V-V-R-N-L-T-K-G-K-E-Y-R-I-R-P-Y-P-E-F-L-M-K-I-M-E-A-G-G-W-L-E-Y-C-L-K-E-V-G-E


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-A-Y-V-K-E-R-I-Y-E-S-M-F-I-I-A-P-N-V-P-E-E-E-R-E-N-L-V-E-R-V-K-K-I-I-E-E-R-V-K-G-K-I-D-K-V-E-R-M-G-M-R-K-F-A-Y-E-I-K-K-F-N-E-G-D-Y-T-V-I-Y-F-R-C-D-G-Q-N-L-Q-E-L-E-N-F-Y-R-V-T-P-E-I-I-R-W-Q-T-F-R-R-F-D-L-E-K-K-E-R-K-A-Q-R-E-K-A-A-A-E-A-T-E-S-S-E-G-G-S-E-D


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-A-Y-R-R-R-K-K-K-I-K-K-C-R-L-C-E-M-K-L-D-Y-V-D-Y-K-D-T-R-L-L-S-E-F-L-T-D-K-G-K-I-I-P-K-R-L-T-G-N-C-S-K-H-Q-R-M-V-K-V-A-I-K-R-A-R-Q-M-G-L-L-P-Y-L-K-I


### FUNCTION Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide ### SEQUENCE -M-K-L-S-D-F-I-K-T-E-D-F-K-K-E-K-H-V-P-V-I-E-A-P-E-K-V-K-K-D-E-K-V-Q-I-V-V-T-V-G-K-E-I-P-H-P-N-T-T-E-H-H-I-R-W-I-K-V-F-F-Q-P-D-G-D-P-Y-V-Y-E-V-G-R-Y-E-F-N-A-H-G-E-S-V-Q-G-P-N-I-G-A-V-Y-T-E-P-T-V-T-T-V-V-K-L-N-R-S-G-T-I-I-A-L-S-Y-C-N-I-H-G-L-W-E-S-S-Q-K-I-T-V-E-E


### FUNCTION Carrier of the growing fatty acid chain in fatty acid biosynthesis ### SEQUENCE -M-A-S-R-E-E-I-F-S-K-V-K-S-I-I-S-E-K-L-G-V-D-E-S-Q-V-T-E-E-A-K-L-I-D-D-L-G-A-D-S-L-D-L-V-D-L-V-M-D-F-E-S-E-F-G-V-K-V-D-D-A-D-L-E-K-I-S-T-V-G-D-I-V-S-Y-I-E-K-K-L-G


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-K-K-I-K-S-F-G-G-K-S-L-G-G-G-K-Q-E-K-I-L-K-D-F-A-R-M-Q-E-E-L-Q-K-K-I-Q-E-L-E-E-S-F-S-Q-I-E-V-E-A-S-V-G-G-G-A-V-R-I-V-A-T-C-D-R-R-V-K-D-I-E-I-D-E-D-L-K-E-D-F-D-T-L-K-D-L-L-I-A-G-M-N-E-V-M-E-K-I-E-K-R-R-E-E-E-M-S-K-I-T-Q-Q-F-G-I-P-G-L-M


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-I-V-G-V-G-I-D-V-L-E-V-E-R-V-P-E-K-F-A-E-R-I-L-G-E-S-E-K-R-L-F-L-T-R-K-R-R-R-E-F-I-A-G-R-F-A-L-K-E-A-F-F-K-A-L-G-T-G-L-N-G-H-S-F-T-D-V-E-F-L-E-S-N-G-K-P-V-L-C-V-H-K-D-F-G-F-F-N-Y-A-H-V-S-L-S-H-D-R-F-A-V-A-L-V-V-L-E-K-R-K-G-D-I-I-V-E-G-D-E-S-F-L-R-K-R-F-E-V-L-E-R-S-V-E-G-W-E-I-E-T-S-L-P-P-F-T-L-K-K-L-L-E-S-S-G-C-R-L-V-R-Y-G-N-I-L-I-G-E


### FUNCTION Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE It is the nucleotide exchange factor for DnaK and may function as a thermosensor Unfolded proteins bind initially to DnaJ ### SEQUENCE -M-S-E-K-E-K-K-E-L-T-Q-E-C-E-E-L-K-E-K-Y-K-E-L-E-E-Y-A-K-R-L-K-A-E-Y-E-N-Y-R-E-E-V-A-R-E-K-R-E-L-I-K-N-A-N-E-Y-L-I-S-K-L-I-P-V-L-D-D-F-E-R-A-L-N-Q-G-E-K-G-D-A-F-Y-E-G-V-K-M-I-Y-K-K-L-L-N-V-L-E-K-E-G-L-T-K-I-H-V-G-E-K-F-D-P-F-E-H-E-A-V-E-R-V-E-T-E-D-V-E-E-Y-T-I-L-E-V-V-E-S-G-Y-K-F-H-G-K-V-L-K-P-A-K-V-K-V-A-V-K-P-R-K-K-E-E-R-K-V-E-E-P-S-D-K-K-E


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-N-P-A-Y-R-K-A-M-L-E-S-E-I-Q-K-L-L-M-E-A-L-Q-Q-L-R-D-P-R-L-K-K-D-F-V-T-F-S-R-V-E-L-S-K-D-K-R-Y-A-D-V-Y-V-S-F-L-G-T-P-E-E-R-K-E-T-V-E-I-L-N-R-A-K-G-F-F-R-T-F-I-A-K-N-L-R-L-Y-V-A-P-E-I-R-F-Y-E-D-K-G-I-E-A-S-V-K-V-H-Q-L-L-V-Q-L-G-Y-D-P-L-K-D-K-E-K-K-E-E-D-K-E-E-E


### FUNCTION The SecYEG-SecDF-YajC-YidC holo-translocon  protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions ### SEQUENCE -M-P-E-I-I-Y-A-A-A-P-G-A-S-N-G-T-T-T-T-A-T-G-G-G-W-G-S-L-L-F-M-L-I-F-F-I-A-I-F-Y-F-M-I-I-L-P-Q-R-R-R-E-K-Q-F-Q-Q-M-I-S-Q-M-K-R-G-D-T-V-V-T-I-G-G-I-V-G-K-V-I-D-I-K-K-D-T-V-K-I-K-T-A-N-S-T-E-L-E-I-T-K-R-A-I-S-T-V-I-K-E-R-S-Q-E-N-Q-E-G


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-V-I-L-L-R-D-V-P-K-I-G-K-K-G-E-I-K-E-V-S-D-G-Y-A-R-N-Y-L-I-P-R-G-F-A-K-E-Y-T-E-G-L-E-R-A-I-K-H-E-K-E-I-E-K-R-K-K-E-R-E-R-E-E-S-E-K-I-L-K-E-L-K-K-R-T-H-V-V-K-V-K-A-G-E-G-G-K-I-F-G-A-V-T-A-A-T-V-A-E-E-I-S-K-T-T-G-L-K-L-D-K-R-W-F-K-L-D-K-P-I-K-E-L-G-E-Y-S-L-E-V-S-L-P-G-G-V-K-D-T-I-K-I-R-V-E-R-E-E


### FUNCTION Involved in resistance toward heavy metals ### SEQUENCE -M-I-L-V-Y-S-T-F-P-N-E-E-K-A-L-E-I-G-R-K-L-L-E-K-R-L-I-A-C-F-N-A-F-E-I-R-S-G-Y-W-W-K-G-E-I-V-Q-D-K-E-W-A-A-I-F-K-T-T-E-E-K-E-K-E-L-Y-E-E-L-R-K-L-H-P-Y-E-T-P-A-I-F-T-L-K-V-E-N-V-L-T-E-Y-M-N-W-L-R-E-S-V-L


### FUNCTION In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts an anti-sigma factor and thus releases a sigma factor from inhibition ### SEQUENCE -M-F-P-Y-K-I-V-D-D-V-V-I-L-M-P-N-K-E-L-N-I-E-N-A-H-L-F-K-K-W-V-F-D-E-F-L-N-K-G-Y-N-K-I-F-L-V-L-S-D-V-E-S-I-D-S-F-S-L-G-V-I-V-N-I-L-K-S-I-S-S-S-G-G-F-F-A-L-V-S-P-N-E-K-V-E-R-V-L-S-L-T-N-L-D-R-I-V-K-I-Y-D-T-I-S-E-A-M-E-E-V-R-R-K


### FUNCTION Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently  May also act as a chaperone or modulator of proteins involved in DNA or RNA processing ### SEQUENCE -M-R-K-P-I-E-H-T-A-D-I-A-Y-E-I-S-G-N-S-Y-E-E-L-L-E-E-A-R-N-I-L-L-E-E-E-G-I-V-L-D-T-E-E-K-E-K-M-Y-P-L-E-E-T-E-D-A-F-F-D-T-V-N-D-W-I-L-E-I-S-K-G-W-A-P-W-R-I-K-R-E-G-N-E-L-K-V-T-F-R-K-I-R-K-K-E-G-T-E-I-K-A-L-T-Y-H-L-L-K-F-E-R-D-G-D-V-L-K-T-K-V-V-F-D-T


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA ### SEQUENCE -M-V-S-L-D-P-E-K-K-N-E-I-I-K-E-F-Q-I-H-E-N-D-T-G-S-V-E-V-Q-I-A-L-L-T-A-R-I-K-H-L-T-E-H-L-R-K-H-P-K-D-F-H-S-R-R-G-L-M-K-M-I-G-R-R-R-K-M-L-K-Y-L-R-H-K-K-P-E-V-Y-R-E-L-I-A-K-L-G-I-R-K


### FUNCTION A scaffold on which IscS assembles Fe-S clusters Subsequently gives the nascent cluster to other proteins It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters ### SEQUENCE -M-V-F-K-M-M-Y-S-E-A-I-L-D-Y-A-N-S-K-K-F-R-G-K-L-D-D-A-T-V-I-E-E-G-K-N-I-S-C-G-D-E-I-T-L-Y-L-K-V-E-D-G-V-V-K-D-A-K-F-E-G-M-G-C-V-I-S-Q-A-S-A-S-L-M-L-E-R-I-I-G-E-R-V-E-E-I-F-S-L-I-E-E-A-E-K-M-S-R-G-E-N-F-D-E-G-K-L-K-N-V-T-L-M-S-D-I-K-N-Y-P-A-R-V-K-C-F-I-L-A-W-K-T-L-K-E-A-L-K-K-I-S-R-P


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-V-N-P-F-I-K-E-A-K-E-K-M-K-R-T-L-E-K-I-E-D-E-L-R-K-M-R-T-G-K-P-S-P-A-I-L-E-E-I-K-V-D-Y-Y-G-V-P-T-P-V-N-Q-L-A-T-I-S-I-S-E-E-R-T-L-V-I-K-P-W-D-K-S-V-L-S-L-I-E-K-A-I-N-A-S-D-L-G-L-N-P-I-N-D-G-N-V-I-R-L-V-F-P-S-P-T-T-E-Q-R-E-K-W-V-K-K-A-K-E-I-V-E-E-G-K-I-A-I-R-N-I-R-R-E-I-L-K-K-I-K-E-D-Q-K-E-G-L-I-P-E-D-D-A-K-R-L-E-N-E-I-Q-K-L-T-D-E-F-I-E-K-L-D-E-V-F-E-I-K-K-E-E-I-M-E-F


### FUNCTION In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts an anti-sigma factor and thus releases a sigma factor from inhibition ### SEQUENCE -M-N-N-L-K-L-D-I-V-E-Q-D-D-K-A-I-V-R-V-Q-G-D-I-D-A-Y-N-S-S-E-L-K-E-Q-L-R-N-F-I-S-T-T-S-K-K-K-I-V-L-D-L-S-S-V-S-Y-M-D-S-A-G-L-G-T-L-V-V-I-L-K-D-A-K-I-N-G-K-E-F-I-L-S-S-L-K-E-S-I-S-R-I-L-K-L-T-H-L-D-K-I-F-K-I-T-D-T-V-E-E-A


### FUNCTION This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself It is important during the early stages of 50S assembly ### SEQUENCE -M-A-R-Y-F-P-V-Q-K-T-T-M-I-K-P-E-E-V-E-R-K-W-Y-V-V-D-A-S-G-K-V-L-G-R-L-A-T-R-I-A-K-I-L-M-G-K-H-K-P-N-Y-T-P-H-V-D-T-G-D-Y-V-I-V-V-N-A-D-K-V-V-L-T-G-K-K-L-D-Q-K-V-Y-Y-W-H-S-G-Y-P-G-G-L-K-S-L-T-A-R-Q-M-L-E-K-H-P-E-R-L-I-W-L-A-V-K-R-M-L-P-K-N-R-K-G-R-K-M-L-K-R-L-K-V-Y-A-S-P-E-H-P-H-Q-A-Q-K-P-E-P-I-E-L


### FUNCTION This protein binds to 23S rRNA in the presence of protein L20 ### SEQUENCE -M-L-Y-A-I-V-E-T-A-G-R-Q-Y-R-V-E-E-G-K-I-L-Y-T-E-K-Q-K-D-Y-S-P-G-D-E-I-V-F-D-R-V-V-F-V-R-K-D-G-E-V-L-V-G-K-P-Y-V-E-G-A-K-V-V-G-K-V-L-E-H-A-K-A-R-K-V-K-T-V-K-Y-R-P-R-K-N-S-K-V-E-K-G-H-R-Q-W-Y-T-A-I-K-I-E-K-I-E-L


### FUNCTION Necessary for normal cell division and for the maintenance of normal septation ### SEQUENCE -M-I-I-R-D-V-E-L-V-K-V-A-R-T-P-G-D-Y-P-P-P-L-K-G-E-V-A-F-V-G-R-S-N-V-G-K-S-S-L-L-N-A-L-F-N-R-K-I-A-F-V-S-K-T-P-G-K-T-R-S-I-N-F-Y-L-V-N-S-K-Y-Y-F-V-D-L-P-G-Y-G-Y-A-K-V-S-K-K-E-R-M-L-W-K-R-L-V-E-D-Y-F-K-N-R-W-S-L-Q-M-V-F-L-L-V-D-G-R-I-P-P-Q-D-S-D-L-M-M-V-E-W-M-K-S-L-N-I-P-F-T-I-V-L-T-K-M-D-K-V-K-M-S-E-R-A-K-K-L-E-E-H-R-K-V-F-S-K-Y-G-E-Y-T-I-I-P-T-S-S-V-T-G-E-G-I-S-E-L-L-D-L-I-S-T-L-L-K-E-N


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-R-K-R-G-G-S-S-K-K-Q-K-K-V-S-F-D-Y-G-V-V-H-I-K-S-T-F-N-N-T-I-I-T-L-T-D-K-D-G-N-T-L-T-W-A-S-G-G-T-V-G-F-E-G-T-R-K-G-T-P-Y-A-A-Q-L-A-A-D-K-V-A-R-E-A-L-R-M-G-I-K-K-V-D-V-L-V-K-G-P-G-P-G-R-E-P-A-I-R-T-L-Q-G-A-G-L-E-I-N-Q-I-K-D-V-T-P-I-P-F-N-G-C-R-P-K-K-R-R-R-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-V-G-V-E-L-P-N-N-K-K-V-W-V-A-L-T-Y-I-Y-G-I-G-R-S-R-S-F-E-I-L-K-N-T-G-I-D-P-E-K-R-V-G-D-L-T-D-E-E-I-S-K-I-T-K-Y-I-Q-D-H-F-K-V-E-G-E-L-R-S-E-V-E-R-N-I-R-R-L-I-E-I-G-C-Y-R-G-I-R-H-K-L-G-L-P-V-R-G-Q-K-T-R-S-N-A-R-T-R-K-G-P-R-P-S-R-I-K-T-K-K-K-S-S


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-R-L-E-D-L-R-P-T-P-G-A-M-K-K-R-K-R-V-G-R-G-P-G-S-G-H-G-K-T-S-G-R-G-H-K-G-Q-K-A-R-G-S-G-K-V-H-I-W-F-E-G-G-Q-T-P-L-Q-R-R-L-P-K-R-G-F-K-N-I-N-K-K-V-Y-A-V-V-N-V-K-V-L-E-E-R-F-E-A-N-E-E-V-T-P-E-K-L-I-E-R-K-I-I-K-D-L-K-D-G-V-K-I-L-G-D-G-E-L-T-K-P-L-V-V-K-A-H-A-F-S-K-S-A-V-E-K-I-E-S-A-G-G-K-A-E-V-I


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-E-T-Q-G-V-M-K-E-I-Q-Y-E-E-F-E-E-K-I-I-E-I-R-R-T-S-K-V-T-K-G-G-K-N-L-S-F-R-V-V-A-I-V-G-N-K-N-G-K-V-G-L-G-I-G-K-A-R-E-V-P-E-A-I-R-K-A-I-S-A-A-K-R-N-I-V-E-V-P-V-I-N-G-T-I-P-H-E-V-I-G-R-Q-D-A-S-K-V-L-L-K-P-A-A-P-G-T-G-I-I-A-G-G-T-V-R-A-V-V-E-L-A-G-I-Q-N-I-L-T-K-S-L-G-S-T-N-P-L-N-L-A-L-A-T-M-N-G-L-K-N-L-L-D-P-R-K-V-A-K-L-R-D-I-S-V-E-E-V-F-K-G-V-R-R-E-N-N-A


### FUNCTION Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ### SEQUENCE -M-I-R-I-L-G-E-G-K-G-S-K-L-L-E-N-L-K-E-K-L-E-E-I-V-K-K-E-I-G-D-V-H-V-N-V-I-L-V-S-E-D-E-I-K-E-L-N-Q-Q-F-R-G-Q-D-R-P-T-D-V-L-T-F-P-L-M-E-E-D-V-Y-G-E-I-Y-V-C-P-L-I-V-E-E-N-A-R-E-F-N-N-T-F-E-K-E-L-L-E-V-V-I-H-G-I-L-H-L-A-G-Y-D-H-E-F-E-D-K-N-S-K-E-M-F-E-K-Q-K-K-Y-V-E-E-V-W-G-E-W-R-S-N-P-S-E-D-S-D-P-G-K-R


### FUNCTION Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation ### SEQUENCE -M-R-R-I-S-I-V-L-L-I-V-F-A-T-S-I-F-P-F-S-I-W-N-S-A-G-E-S-E-Y-K-N-L-L-S-I-K-K-A-S-K-V-G-D-I-L-T-I-V-I-R-E-S-N-N-V-S-S-E-R-E-S-L-E-I-Q-K-T-L-L-N-I-L-G-N-V-V-N-A-A-A-G-V-N-L-N-N-F-I-P-I-N-N-N-S-P-E-R-Q-R-G-G-K-V-Q-S-S-V-V-A-K-I-S-A-V-V-V-D-I-D-P-Y-G-N-L-V-V-E-G-R-K-T-I-K-V-D-K-D-Y-Q-E-I-I-V-K-G-K-V-R-P-D-D-I-E-I-G-N-E-V-D-S-S-K-L-A-D-S-E-I-W-V-N-G-K-L-V-F-S-E-E-P-G-K-E-S-F-F-D-K-I-L-A-F-L-A-G-L-F-T


### FUNCTION A probable RNA chaperone Forms a complex with KhpB which binds to cellular RNA and controls its expression Plays a role in peptidoglycan  homeostasis and cell length regulation ### SEQUENCE -M-K-E-L-L-E-K-I-L-R-G-I-V-K-H-P-E-E-V-V-V-M-E-F-D-E-E-G-K-K-V-Y-E-I-V-V-N-E-E-D-V-G-Q-V-I-G-K-D-G-R-T-I-K-S-L-K-I-L-L-S-A-L-M-G-D-S-K-E-I-T-I-K-V-V-R


### FUNCTION An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region Essential for efficient processing of 16S rRNA May be needed both before and after RbfA during the maturation of 16S rRNA It has affinity for free ribosomal 30S subunits but not for 70S ribosomes ### SEQUENCE -M-I-R-T-I-Q-D-L-L-N-E-R-V-A-I-G-K-I-V-N-T-H-G-L-K-G-E-V-K-F-F-P-Y-T-N-S-E-E-I-V-K-N-L-S-S-V-V-L-Y-N-S-E-K-K-A-F-Y-N-L-T-V-E-S-V-R-R-M-N-K-L-F-L-I-R-F-K-S-I-D-T-I-E-A-A-E-R-I-K-G-C-E-V-F-I-K-Y-E-E-L-P-K-L-S-E-D-E-Y-Y-F-Y-E-I-L-D-C-D-V-F-Y-E-S-G-E-N-V-G-K-V-V-D-I-I-E-T-G-S-N-D-V-L-V-V-R-K-K-K-K-E-T-L-I-P-M-T-K-D-C-I-V-E-I-D-K-G-A-K-K-I-I-A-K-E-M-E-W-I


### FUNCTION This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site ### SEQUENCE -M-D-H-L-V-K-I-I-E-K-K-Y-E-K-K-E-I-P-D-F-R-P-G-D-T-V-R-V-H-V-K-V-I-E-G-D-R-E-R-T-Q-V-F-E-G-I-V-I-A-K-R-G-S-G-I-N-K-T-F-T-V-R-R-I-G-S-H-G-V-G-V-E-R-I-F-P-V-H-S-P-V-V-E-K-I-E-V-V-R-K-G-K-V-R-R-A-K-L-Y-Y-L-R-N-V-R-G-K-I-R-I-K-E-R-R-D


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-G-I-G-V-N-T-D-L-P-R-N-E-Q-I-K-A-P-K-V-R-V-V-D-E-N-G-K-M-I-G-V-M-P-T-R-K-A-L-E-L-A-R-E-K-G-L-D-L-V-L-V-A-P-N-E-N-P-P-V-A-R-I-M-D-Y-G-K-Y-K-Y-Q-L-T-K-K-Q-K-E-N-K-K-K-P-V-Q-M-K-Q-M-K-F-R-L-K-I-D-E-H-D-Y-Q-T-K-V-K-H-I-R-R-F-L-E-D-G-H-K-V-R-V-V-V-M-F-I-G-R-E-M-M-F-A-E-K-G-K-E-I-L-E-R-V-I-K-D-T-E-D-L-A-T-V-E-S-P-P-K-M-E-G-R-D-M-W-M-V-L-K-P-K-N-S


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-R-V-K-R-A-V-H-A-K-K-K-R-K-K-Y-L-K-A-A-K-G-Y-R-G-A-L-S-R-R-Y-K-L-A-K-Q-M-Y-V-R-S-K-W-Y-S-Y-V-G-R-K-Q-K-K-R-D-M-R-K-L-W-I-T-R-I-N-I-A-A-R-N-E-G-L-K-Y-S-E-L-I-H-G-L-K-L-A-G-V-S-I-N-R-K-M-L-S-E-L-A-V-N-D-P-E-A-F-K-E-Y-V-K-I-A-K-E-A-L-A-S


### FUNCTION Associates with the EF-TuGDP complex and induces the exchange of GDP to GTP It remains bound to the aminoacyl-tRNAEF-TuGTP complex up to the GTP hydrolysis stage on the ribosome ### SEQUENCE -M-E-I-S-M-D-L-I-K-K-L-R-E-M-T-G-A-G-I-L-D-C-K-K-A-L-E-E-A-N-G-D-M-E-K-A-V-E-I-L-R-K-K-G-A-A-T-A-E-K-K-A-G-R-T-T-K-E-G-I-I-V-A-Y-V-H-F-N-G-R-I-G-V-L-L-E-M-N-C-E-T-D-F-V-A-R-T-D-E-F-K-E-L-A-Y-N-L-A-K-Q-V-A-A-M-K-P-L-Y-V-R-R-E-D-V-P-A-E-V-I-E-K-E-K-E-I-Y-R-A-Q-I-K-D-K-P-E-N-I-V-E-K-I-V-E-G-K-L-E-K-F-F-E-Q-A-C-L-Y-E-Q-T-Y-I-F-D-D-T-K-K-V-K-D-L-I-N-E-L-I-A-K-T-G-E-N-I-R-V-S-R-F-T-R-Y-E-I-G-E-G-Y-E-D


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-R-F-S-A-V-A-G-R-Y-A-R-A-L-L-N-V-A-I-E-K-E-K-E-E-E-Y-L-R-F-L-D-L-V-C-Q-I-Y-E-S-S-R-E-L-F-D-N-P-I-L-K-P-E-K-K-I-S-L-I-K-E-I-M-K-S-F-G-Q-E-M-D-E-F-Q-E-R-F-L-T-L-V-F-E-R-K-R-Q-K-L-L-R-N-I-R-D-L-F-E-Y-E-K-I-L-S-E-Q-K-V-P-A-N-L-S-I-A-H-S-P-E-D-E-E-L-S-L-L-R-K-F-V-R-K-Y-A-L-K-D-P-V-F-D-I-S-I-D-E-S-L-I-A-G-A-L-V-E-F-E-G-F-R-L-D-T-T-V-Q-G-R-L-K-R-I-A-R-E-A-L-K-R-G-E-M-S


### FUNCTION F is coupled via a rotary mechanism of the central stalk subunits to proton translocation ### SEQUENCE -M-G-F-L-E-I-N-W-T-S-A-A-M-L-M-L-F-V-L-M-V-Y-F-L-N-K-F-L-Y-T-P-F-I-E-M-A-E-K-R-R-K-K-V-E-E-D-L-K-S-A-E-Q-L-K-E-E-A-E-K-M-R-S-E-A-E-R-F-L-S-E-A-R-Q-R-A-D-E-I-V-E-S-A-R-K-E-A-E-A-I-V-E-E-A-R-E-K-A-K-K-E-A-Q-N-I-V-E-S-A-K-T-Q-I-E-V-E-Y-K-K-A-L-E-Q-V-Q-E-R-A-A-E-L-S-V-I-L-A-T-K-L-L-Q-K-V-F-Q-D-E-R-A-R-R-E-Y-L-V-K-I-L-K-E-E-I-E-K-S


### FUNCTION Involved in restoring normal CheY-P levels by dephosphorylating CheY-P It has a greater activity than CheC ### SEQUENCE -M-D-A-R-I-V-N-A-L-I-G-S-V-Y-E-T-I-R-D-V-L-G-I-E-P-K-T-G-K-P-S-T-V-S-H-I-E-I-P-H-S-L-V-T-V-I-G-I-T-G-G-I-E-G-S-L-I-Y-S-F-S-S-E-T-A-L-K-V-V-S-A-M-M-G-G-M-E-Y-N-Q-L-D-E-L-A-L-S-A-I-G-E-L-G-N-M-T-A-G-K-L-A-M-K-L-E-H-L-G-K-H-V-D-I-T-P-P-T-V-V-S-G-R-D-L-K-I-K-S-F-G-V-I-L-K-L-P-I-S-V-F-S-E-E-D-F-D-L-H-L-S-V-K-S-G-G


### FUNCTION The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis ### SEQUENCE -M-V-V-V-G-L-G-N-P-G-P-R-Y-A-F-T-R-H-N-V-G-F-L-F-L-D-F-L-K-N-K-D-W-K-T-E-K-Y-F-A-W-N-K-I-N-L-A-G-N-E-V-A-L-V-K-P-L-T-Y-M-N-L-S-G-L-A-M-P-H-V-L-K-F-F-S-A-S-L-D-D-I-I-V-V-Y-D-D-V-S-L-K-L-G-K-I-R-I-R-K-K-G-S-D-G-G-H-N-G-M-K-S-I-I-Q-A-L-G-T-Q-E-I-K-R-I-R-V-G-I-G-D-K-P-E-G-M-D-L-V-N-F-V-L-G-E-F-S-D-E-E-W-I-I-L-N-K-V-F-E-V-M-K-E-A-L-E-V-I-L-V-E-G-I-E-K-A-M-S-I-Y-N-S-L-E-V-R-A


### FUNCTION Binds directly to 16S ribosomal RNA ### SEQUENCE -M-P-N-I-K-S-A-K-K-R-V-R-V-S-E-K-R-R-L-R-N-K-A-Y-K-T-F-F-K-N-R-I-K-E-V-L-K-A-I-E-N-K-E-P-K-E-V-V-L-E-L-T-R-K-A-Q-A-A-I-D-K-A-V-S-K-G-V-I-H-K-N-Q-G-A-R-R-K-A-R-L-F-E-K-V-N-E-Y-L-R-T-L-E-T-T-Q-E


### FUNCTION Promotes RNA polymerase assembly Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits ### SEQUENCE -M-E-K-I-V-K-F-D-L-K-Y-D-E-L-L-K-K-I-P-Y-K-Y-A-I-P-V-V-V-A-K-R-A-E-A-I-R-E-Y-A-R-P-F-V-I-T-D-D-E-N-Y-V-S-I-A-F-M-E-L-S-L-N-Y-I-R-I-K-N-E-E-I-L-K-A-L-I-P-K-V-K


### FUNCTION Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus GreA releases sequences of 2 to 3 nucleotides ### SEQUENCE -M-K-K-V-R-L-T-R-E-G-Y-E-K-L-K-K-E-L-E-D-L-K-R-K-F-M-Y-E-I-S-E-R-I-K-E-A-R-E-L-G-D-L-S-E-N-S-E-Y-E-A-A-K-N-E-Q-G-R-V-G-S-R-I-M-E-I-E-Q-I-L-S-N-A-E-I-I-E-D-S-E-E-S-D-E-V-T-L-G-K-W-V-V-I-K-N-L-D-T-G-E-E-H-K-F-R-I-V-T-P-Q-E-A-D-F-F-A-Q-K-L-S-S-D-S-P-L-G-K-S-L-L-G-R-K-V-G-D-V-V-K-V-K-A-P-S-G-V-Q-R-Y-Q-V-I-A-V-M-N-K


### FUNCTION Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes ### SEQUENCE -M-K-C-P-F-C-G-S-M-D-T-R-V-L-D-S-R-P-T-L-D-G-T-A-I-R-R-R-R-E-C-S-S-C-G-K-R-F-T-T-Y-E-R-Y-E-E-A-P-V-L-V-V-K-K-D-G-R-R-E-K-F-D-R-E-K-I-K-N-G-M-I-K-A-C-E-K-R-P-V-T-Y-E-Q-I-E-E-A-V-N-R-I-C-L-K-L-R-E-E-G-S-F-E-V-E-T-K-R-I-G-E-L-V-M-E-E-L-K-K-L-D-Q-V-A-Y-V-R-L-A-S-V-Y-R-D-F-R-E-V-D-Q-F-L-E-I-V-K-E-L-K-R-E-K-E-G-E-E-Q


### FUNCTION Involved in peptide bond synthesis Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase ### SEQUENCE -M-I-E-V-G-D-L-K-K-G-M-F-I-I-Y-D-G-E-I-Y-R-V-L-E-A-S-K-H-F-M-G-R-G-S-G-L-I-R-T-K-L-K-N-V-K-T-G-F-V-R-E-V-N-F-P-S-G-E-K-V-Q-E-A-E-L-S-F-R-K-A-Q-Y-L-Y-R-D-G-D-H-Y-Y-F-M-T-L-D-D-Y-E-Q-Y-A-L-S-E-E-E-I-G-D-A-K-Y-Y-L-V-E-N-M-E-V-D-L-V-F-H-E-G-T-P-I-G-I-E-L-P-T-T-V-E-L-T-V-V-E-T-E-P-S-F-K-G-D-T-V-S-G-G-G-K-P-A-V-L-E-T-G-L-K-I-T-V-P-Y-F-I-E-V-G-D-K-I-K-V-D-T-R-T-G-E-Y-V-G-R-A


### FUNCTION Involved in transcription antitermination Required for transcription of ribosomal RNA  operons ### SEQUENCE -M-K-T-P-R-R-R-M-R-L-A-V-F-K-A-L-F-Q-H-E-F-R-R-D-E-D-L-E-Q-I-L-E-E-I-L-D-E-T-Y-D-K-K-A-K-E-D-A-R-R-Y-I-R-G-I-K-E-N-L-S-M-I-D-D-L-I-S-R-Y-L-E-K-W-S-L-N-R-L-S-V-V-D-R-N-V-L-R-L-A-T-Y-E-L-L-F-E-K-D-I-P-I-E-V-T-I-D-E-A-I-E-I-A-K-R-Y-G-T-E-N-S-G-K-F-V-N-G-I-L-D-R-I-A-K-E-H-A-P-K-E-K-F-E-L


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-N-F-E-E-M-M-K-E-L-E-E-I-V-N-R-L-E-N-E-D-L-P-L-E-E-S-I-K-L-F-E-R-G-V-E-L-Y-R-K-C-K-E-I-L-Q-Q-N-R-L-K-I-I-D-V-M-K-E-L-E-G-E-I-D-A-S-G-R-D-Q-E-N-E-L-R


### FUNCTION Required for maturation of 30S ribosomal subunits ### SEQUENCE -M-F-E-E-M-I-L-E-K-V-R-K-E-A-E-R-I-A-E-E-Q-G-L-E-I-F-D-V-Q-Y-R-R-E-S-R-G-W-V-L-R-I-I-I-D-N-P-V-G-Y-V-S-V-R-D-C-E-L-F-S-R-E-M-E-R-F-L-D-R-E-D-F-I-E-H-S-Y-T-L-E-V-S-S-P-G-L-D-R-P-L-R-G-P-R-D-Y-V-R-F-T-G-K-L-A-K-I-V-T-K-D-G-K-T-F-I-G-R-I-E-S-F-V-D-G-T-I-T-I-S-D-E-K-R-K-Y-E-I-N-I-D-D-V-K-R-A-N-L-E-V-E-F


### FUNCTION Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-uracil with 3,4-dihydroxy-2-butanone 4-phosphate This is the penultimate step in the biosynthesis of riboflavin ### SEQUENCE -M-K-V-V-Q-G-D-Y-R-G-E-G-L-K-I-A-V-V-V-P-R-F-N-D-L-V-T-S-K-L-L-E-G-A-L-D-G-L-K-R-H-G-V-S-D-E-N-I-T-V-V-R-I-P-G-S-M-E-A-I-Y-T-L-K-R-L-L-D-L-G-V-H-D-A-I-I-V-L-G-A-V-I-R-G-E-T-Y-H-F-N-V-V-A-N-E-I-G-K-A-V-A-Q-F-N-M-T-S-D-I-P-I-V-F-G-V-L-T-T-D-T-L-E-Q-A-L-N-R-A-G-A-K-S-G-N-K-G-F-E-A-A-M-V-A-I-E-M-A-N-L-R-K-R-L-R-R-D-V-F-E-S-D-S-N-G-R


### FUNCTION Modulates RecA activity ### SEQUENCE -M-D-Y-Y-Q-W-R-K-K-N-R-G-K-K-R-N-L-Q-A-K-K-P-L-N-Y-A-L-R-L-L-K-Y-R-V-R-F-E-D-E-L-R-E-R-L-K-K-Q-G-F-A-D-E-E-V-E-S-T-I-T-T-L-K-K-Q-G-Y-L-D-D-E-K-A-A-Y-L-F-A-L-D-E-M-R-L-K-L-F-G-P-R-V-V-K-M-K-L-K-S-L-G-V-D-E-E-I-I-E-R-A-I-E-K-A-L-E-E-I-D-F-H-E-E-L-K-R-L-K-G-R-F-K-D-R-W-E-L-R-D-Y-L-Y-R-R-G-F-D-S-S-L-I-E-E-I-L-N-K-I-D-G-G-E-E


### FUNCTION Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester ### SEQUENCE -M-R-T-F-I-A-I-D-V-N-E-E-V-K-K-Q-A-S-E-I-I-E-K-L-M-K-R-G-F-G-A-T-W-V-S-E-E-N-M-H-L-T-L-F-F-L-G-E-V-D-E-Q-K-I-S-E-I-A-E-H-L-C-R-R-V-R-G-F-P-S-F-S-F-T-V-K-G-F-G-Y-F-K-R-K-M-S-P-R-V-F-W-L-G-V-E-N-T-D-R-L-M-K-L-Y-E-E-L-R-N-E-L-S-H-H-G-F-S-F-E-E-K-F-V-P-H-I-T-I-G-R-V-K-Y-Y-P-D-K-W-E-K-L-I-E-D-I-D-F-P-P-I-E-V-A-V-D-R-F-K-I-Y-S-S-T-L-T-P-T-G-P-I-Y-K-V-L-Y-E-C-Q-F-E-G-G-L-I-R-Y-A


### FUNCTION Carrier protein involved in the D-alanylation of lipoteichoic acid  by forming an ester bond, probably catalyzed by DltD D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall ### SEQUENCE -M-E-F-R-E-Q-V-L-D-L-L-T-E-V-A-E-N-N-V-I-K-E-N-P-D-V-E-L-F-E-E-G-I-F-D-S-F-Q-T-V-G-L-L-L-E-I-Q-N-K-L-D-I-E-V-S-I-M-D-F-D-R-D-E-W-A-T-P-N-K-I-V-E-V-L-E-E-L-R


### FUNCTION Multidrug exporter Is implicated for the resistance to bacteriocidal quaternary ammonium compounds ### SEQUENCE -M-K-N-W-I-F-L-A-V-S-I-F-G-E-V-I-A-T-S-A-L-K-S-S-H-G-F-T-R-L-V-P-S-V-V-V-V-A-G-Y-G-L-A-F-Y-F-L-S-L-A-L-K-S-I-P-V-G-I-A-Y-A-V-W-A-G-L-G-I-V-L-V-A-A-I-A-W-I-F-H-G-Q-K-L-D-F-W-A-F-I-G-M-G-L-I-V-S-G-V-A-V-L-N-L-L-S-K-V-S-A-H


### FUNCTION Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions ### SEQUENCE -M-S-E-H-I-V-N-V-T-D-A-S-F-E-Q-D-V-L-K-A-D-G-P-V-L-V-D-Y-W-A-E-W-C-G-P-C-K-M-I-A-P-V-L-D-E-V-A-R-D-Y-Q-G-K-L-K-V-C-K-L-N-I-D-E-N-Q-D-T-P-P-K-Y-G-V-R-G-I-P-T-L-M-L-F-K-D-G-N-V-E-A-T-K-V-G-A-L-S-K-S-Q-L-A-A-F-L-D-A-N-I


### FUNCTION Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein ### SEQUENCE -M-S-I-P-T-V-K-A-K-L-L-Q-G-R-K-G-L-I-V-G-I-A-N-D-R-S-I-A-W-G-R-A-R-A-F-R-A-L-G-A-E-I-A-V-T-Y-L-N-D-K-A-L-P-L-V


### FUNCTION Required for rescue of stalled ribosomes mediated by trans-translation Binds to transfer-messenger RNA , required for stable association of tmRNA with ribosomes tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB tmRNA is encoded by the ssrA gene ### SEQUENCE -M-K-I-I-S-D-N-K-R-G-M-H-N-Y-K-V-I-D-K-Y-E-A-G-I-S-L-M-G-W-E-V-K-S-A-R-A-N-T-V-S-L-L-N-S-Y-C-F-F-R-K-G-E-I-F-L-C-N-A-Q-F-K-Q-Y-M-L-V-K-C-D-E-T-R-D-R-K-L-L-M-H-K-N-E-I-V-R-L-Q-S-K-L-H-K-L-G-H-A-T-I-I-P-S-K-I-Y-F-D-N-R-S-R-I-K-I-E-I-A-L-V-Q-G-M-K-K-T-D-K-R-E-E-I-K-K-R-D-N-E-R-Y-I-K-K-V-L-K-N-V-Y


### FUNCTION Required for insertion of 4Fe-4S clusters for at least IspG ### SEQUENCE -M-S-D-I-D-Q-I-P-L-T-F-T-D-A-A-A-K-K-V-K-S-L-I-E-G-E-D-N-P-N-L-R-L-R-V-Y-I-T-G-G-G-C-S-G-F-Q-Y-G-F-T-F-D-D-K-I-N-E-G-D-L-T-I-E-N-Q-N-V-G-L-I-V-D-P-M-S-L-Q-Y-L-I-G-G-S-V-D-Y-T-E-G-L-D-G-S-R-F-V-V-Q-N-P-N-A-S-S-T-C-G-C-G-S-S-F-S-I


### FUNCTION Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage ### SEQUENCE -M-I-D-S-D-G-F-R-P-N-V-G-I-I-L-A-N-E-A-G-Q-V-L-W-A-R-R-I-N-Q-E-A-W-Q-F-P-Q-G-G-I-N-D-R-E-T-P-E-E-A-L-Y-R-E-L-N-E-E-V-G-L-E-A-G-D-V-R-I-L-A-C-T-R-G-W-L-R-Y-R-L-P-Q-R-L-V-R-T-H-S-Q-P-L-C-I-G-Q-K-Q-K-W-F-L-L-R-L-M-S-D-E-A-R-V-R-M-D-I-T-S-K-P-E-F-D-G-W-R-W-V-S-Y-W-Y-P-L-G-Q-V-V-T-F-K-R-E-V-Y-R-R-A-L-K-E-L-A-P-R-L-L-A-R-D


### FUNCTION Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors ### SEQUENCE -I-I-A-G-T-A-R-S-M-G-I-T-V-E-G


### FUNCTION Involved in urease metallocenter assembly Binds nickel Probably functions as a nickel donor during metallocenter assembly ### SEQUENCE -M-V-L-T-E-V-Y-R-N-V-D-D-I-P-N-I-G-S-Y-H-I-E-T-A-M-V-K-S-D-D-L-M-K-N-I-L-R-V-K-T-D-H-G-N-E-Y-G-I-R-L-D-N-E-D-Q-I-L-E-N-G-S-A-F-K-L-G-D-K-Q-L-L-V-L-S-V-I-A-D-E-M-I-E-I-T-P-R-D-I-N-E-M-G-L-V-A-H-F-L-G-N-L-H-K-P-V-Q-I-K-D-G-K-I-S-L-L-L-D-K-V-V-I-K-M-L-D-K-H-D-I-N-Y-E-L-K-K-V-Q-L-D-Q-P-L-E-Y-L-D-L-T-K


### FUNCTION Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis May increase the efficiency of translation by recycling ribosomes from one round of translation to another ### SEQUENCE -M-A-A-Y-N-K-A-D-L-E-R-R-M-K-G-A-V-E-S-L-K-S-D-F-S-G-L-R-T-G-R-A-S-T-S-L-L-D-P-V-T-V-D-V-Y-G-A-N-M-P-L-N-Q-V-A-T-V-S-V-P-E-P-R-M-I-T-V-Q-V-W-D-K-S-N-V-T-P-V-D-K-A-I-R-S-A-G-L-G-L-N-P-V-V-D-G-Q-M-L-R-L-P-I-P-D-L-T-E-E-R-R-K-E-L-A-K-L-V-G-Q-Y-S-E-K-A-R-I-A-V-R-N-V-R-R-D-G-N-D-Q-I-K-Q-D-E-K-K-N-E-I-S-E-D-E-K-K-R-F-E-N-E-V-Q-K-L-T-D-K-T-I-A-D-I-D-A-L-A-V-H-K-E-K-E-I-L-G-K


### FUNCTION Catalyzes the conversion of ### SEQUENCE -M-V-D-V-S-D-K-V-E-T-K-R-T-A-V-A-E-G-R-V-V-M-R-P-E-T-L-A-L-V-I-A-G-R-A-G-K-G-D-V-L-G-I-A-R-V-A-G-I-M-A-A-K-R-T-A-D-P-K-N-S-K-S-F-S-R-V-L-L-E-R-P-R-A-H-S-I


### FUNCTION Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-G-N-M-G-T-S-E-L-L-K-H-I-Y-D-I-N-L-S-Y-L-L-L-A-Q-R-L-I-N-D-E-K-A-F-C-K-V-F-V-G-G-I-Q-G-K-G-G-A-G-Y-L-D-A-T-G-L-L-P-Q-M-V-K-L-A-E-T-N-Q-L-I-C-H-F-R-F-R-R-I-T-I-T-I-Q-S-L-D-S-G-N-Q-R-V-D-D-L-Q-Q-I-H-T-G-I-L-L-S-S-N-L-L-Q-Q-L-T-S-K-E-E-N-L-P-K-K-R-A


### FUNCTION Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-A-E-K-S-I-V-Q-E-A-K-D-I-Q-L-A-M-E-L-I-S-L-G-A-R-L-Q-M-L-E-S-E-T-Q-L-S-R-G-R-L-I-K-L-Y-K-E-L-R-G-S-P-P-P-K-G-M-L-P-F-S-T-D-W-F-M-T-W-E-Q-N-I-H-S-S-M-F-Y-N-A-Y-S-F-L-I-K-N-G-Q-C-S-G-V-K-A-V-I-K-S-Y-R-L-Y-L-E-Q-C-A-P-Q-S-D-S-P-L-L-A-L-T-R-A-W-T-L-V-R-F-V-D-S-G-M-L-Q-L-S-S-C-N-C-C-K-G-M-F-I-Y-P-R-L-H-Q-P-K-N-S-F-V-C-S-L-C-Q-P-P-S-R-A-V-K-R-L-K-L-S-Q-N-L-A-D-I-I-P-R-L-L-D-E-Q-V-K-H-A-V


### FUNCTION Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions, however the precise biochemical function of VdcD in metabolism of phenolic acid is unknown ### SEQUENCE -M-N-H-L-P-V-E-C-P-R-C-A-F-E-D-I-S-L-L-A-T-S-P-V-P-G-V-W-D-V-V-Q-C-G-R-C-L-Y-T-W-R-T-I-E-P-A-R-R-T-R-R-D-A-Y-P-D-S-F-K-L-T-A-E-D-I-E-N-A-I-E-V-P-A-V-P-P-L-L-K


### FUNCTION Electron-transport protein of unknown function ### SEQUENCE -M-R-K-I-P-I-I-A-G-V-F-S-L-L-I-T-S-C-T-F-A-A-S-L-Q-D-D-M-N-I-L-I-A-N-L-G-I-V-S-S-S-T-D-T-K-V-I-T-S-S-L-E-K-M-R-N-A-A-L-D-A-Q-K-A-I-P-P-K-L-E-G-K-A-E-D-S-P-E-I-K-D-Y-R-H-G-F-D-L-L-I-E-Q-I-D-K-T-K-Q-W-A-E-E-G-N-I-Q-E-V-K-K-S-V-G-E-V-I-N-I-R-N-T-Y-H-S-R-Y-R


### FUNCTION IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins ### SEQUENCE -M-I-I-K-R-D-M-R-Q-D-K-R-A-A-P-K-A-P-I-N-E-N-I-S-A-R-E-V-R-L-I-G-A-D-G-E-Q-I-G-I-V-S-I-D-E-A-L-R-I-A-E-E-A-K-L-D-L-V-E-I-S-A-D-A-V-P-P-V-C-R-V-M-D-Y-G-K-S-I-F-E-K-K-K-Q-I-A-A-A-K-K-N-Q-K-Q-I-Q-V-K-E-I-K-F-R-P-G-T-E-E-G-D-Y-Q-V-K-L-R-N-L-V-R-F-L-S-D-G-D-R-A-K-V-S-L-R-F-R-G-R-E-M-A-H-Q-E-L-G-M-E-L-L-K-R-V-E-A-D-L-Q-E-Y-G-S-V-E-Q-H-P-K-M-E-G-R-Q-L-I-M-V-I-A-P-K-K-K-K


### FUNCTION Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit It is not involved in the protein synthesizing functions of that subunit ### SEQUENCE -M-A-R-V-K-R-G-V-I-A-R-K-R-H-K-K-I-L-K-L-A-K-G-Y-Y-G-A-R-S-R-V-F-R-V-A-K-Q-A-V-I-K-A-G-Q-Y-A-Y-R-D-R-R-Q-K-K-R-Q-F-R-A-L-W-I-A-R-I-N-A-G-A-R-N-N-G-L-S-Y-S-R-L-I-A-G-L-K-K-A-S-I-E-I-D-R-K-V-L-A-D-L-A-V-N-E-K-A-A-F-A-A-I-V-E-K-A-K-A-T-L-A


### FUNCTION Regulates the transcription of the pyrimidine nucleotide  operon in response to exogenous pyrimidines ### SEQUENCE -M-S-L-P-N-P-A-E-L-L-P-R-M-A-S-D-L-R-A-H-L-A-E-R-G-I-E-R-P-R-F-V-G-I-H-T-G-G-I-W-V-A-E-A-L-L-R-E-L-G-N-Q-E-P-L-G-T-L-D-V-S-F-Y-R-D-D-F-T-Q-N-G-L-H-P-Q-V-R-P-S-A-L-P-F-E-I-D-G-Q-H-L-V-L-V-D-D-V-L-M-S-G-R-T-I-R-A-A-L-N-E-L-F-D-Y-G-R-P-A-S-V-T-L-V-C-L-L-D-L-N-A-R-E-L-P-I-R-P-D-V-V-G-Q-T-L-S-L-G-R-D-E-R-V-K-L-V-G-P-A-P-L-A-L-E-R-K-V-L-S-S-A-S


### FUNCTION Channel that opens in response to stretch forces in the membrane lipid bilayer May participate in the regulation of osmotic pressure changes within the cell ### SEQUENCE -M-W-K-D-F-K-E-F-A-M-K-G-N-V-V-D-L-A-V-G-V-I-I-G-G-A-F-G-K-I-V-T-S-L-V-N-D-V-I-M-P-I-L-G-L-I-L-G-G-I-N-F-T-S-A-K-L-T-L-H-G-L-N-S-E-K-P-L-T-L-N-Y-G-Q-F-I-Q-N-I-L-D-F-L-I-I-S-F-S-I-F-L-F-I-R-L-I-N-R-F-K-R-K-E-E-A-V-E-E-A-K-I-P-E-I-S-R-E-E-E-L-L-G-E-I-R-D-L-L-K-E-K-N-K


### FUNCTION One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit Associates with free 30S ribosomal subunits  Required for efficient processing of 16S rRNA May interact with the 5'-terminal helix region of 16S rRNA ### SEQUENCE -M-G-N-S-F-R-S-D-R-V-A-V-E-I-Q-R-E-I-N-D-I-L-R-N-K-V-R-D-P-R-V-Q-D-V-N-I-T-D-V-Q-L-T-G-D-L-S-Q-A-T-V-Y-Y-S-L-L-S-N-L-A-S-D-N-E-K-A-A-T-A-L-K-K-A-T-G-L-F-K-S-E-L-A-K-R-M-T-I-F-K-I-P-D-L-T-F-A-K-D-E-S-V-E-Y-G-S-K-I-D-E-I-L-T-W-A


### FUNCTION Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides ### SEQUENCE -M-R-S-T-T-P-I-N-T-T-P-I-N-Q-L-G-Y-E-A-C-R-D-E-L-I-E-V-V-R-L-L-E-Q-G-G-L-N-L-D-M-S-L-K-L-W-E-R-G-E-Q-L-A-K-R-C-E-E-H-L-D-G-A-R-Q-R-V-A-D-V-L-S-A-R-Q-V-E-E-A


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-P-P-K-K-A-N-A-A-G-P-K-K-G-Q-K-T-R-K-R-E-K-K-N-I-P-Y-G-A-A-H-I-K-S-T-F-N-N-T-I-V-T-I-T-D-Q-Q-G-N-V-I-A-W-A-S-S-G-H-V-G-F-K-G-S-R-K-S-T-P-F-A-A-Q-L-A-A-E-N-A-A-R-K-A-Q-E-H-G-V-R-K-V-D-V-F-V-M-G-P-G-S-G-R-E-T-A-I-R-S-L-Q-A-A-G-L-E-V-G-A-I-S-D-V-T-P-Q-P-H-N-G-C-R-P-P-K-R-R-R-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-L-V-G-V-D-L-P-R-D-K-R-M-E-V-A-L-T-Y-I-Y-G-I-G-R-T-R-A-N-E-I-L-E-A-T-G-I-E-R-D-L-R-T-R-D-L-T-D-D-Q-L-T-H-L-R-D-Y-I-E-A-N-L-K-V-E-G-D-L-R-R-E-V-Q-A-D-I-R-R-K-M-E-I-G-C-Y-Q-G-L-R-H-R-R-G-L-P-V-R-G-Q-R-T-K-T-N-A-R-T-R-K-G-P-K-R-T-I-A-G-K-K-K-A-R


### FUNCTION Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein ### SEQUENCE -M-G-I-V-G-V-G-I-D-L-V-S-I-P-D-F-A-E-Q-V-S-Q-P-G-T-V-F-M-T-I-F-T-P-G-E-R-R-D-A-S-V-K-S-S-S-A-V-C-H-L-A-A-R-W-A-V-K-E-A-V-I-K-A-W-S-G-S-R-F-A-Q-R-P-M-L-P-E-N-I-H-R-D-I-E-V-V-N-D-M-W-G-R-P-R-V-R-L-T-G-A-I-A-K-H-L-T-D-V-T-I-H-V-S-L-T-H-E-G-D-I-A-A-A-V-V-I-L-E-V-L


### FUNCTION May help in the organization of the PsaE and PsaF subunits ### SEQUENCE -M-F-K-I-F-S-T-K-W-F-R-S-A-P-V-V-A-T-I-W-I-V-I-T-A-G-I-L-V-E-W-N-R-F-V-P-D-L-L-F-H-P-G-L


### FUNCTION Cleaves peptides in various proteins in a process that requires ATP hydrolysis Has a chymotrypsin-like activity Plays a major role in the degradation of misfolded proteins ### SEQUENCE -M-R-N-D-D-D-Q-E-E-K-K-T-E-L-P-L-G-K-E-T-E-A-N-L-F-K-S-R-S-I-F-I-Y-G-T-I-T-Q-E-L-A-Q-K-V-C-S-Q-L-V-A-L-A-A-A-S-D-D-D-I-R-L-F-V-N-S-P-G-G-H-V-E-S-G-D-S-I-H-D-M-I-K-F-V-K-P-K-V-W-T-I-G-T-G-W-V-A-S-A-G-A-L-I-Y-V-A-A-P-K-E-Q-R-L-C-L-P-N-T-R-F-L-L-H-Q-P-S-G-G-T-R-G-M-A-S-D-I-E-I-Q-A-R-E-I-I-K-M-N-E-R-L-N-R-I-F-S-E-A-T-G-Q-P-V-D-K-I-A-K-D-T-D-R-D-Y-W-L-G-A-E-E-A-K-A-Y-G-L-V-S-R-I-V-T-S-I-A-E-I


### FUNCTION Toxic component of a type II toxin-antitoxin  system An RNase ### SEQUENCE -M-S-F-V-D-G-S-V-I-V-A-I-L-N-E-E-P-G-F-E-E-L-E-K-R-L-S-D-A-D-G-K-L-C-V-S-P-L-V-R-F-E-A-V-A-A-L-T-R-L-R-I-I-A-T-K-G-K-A-D-R-S-D-L-I-G-E-A-R-E-L-V-D-S-F-I-Q-A-L-S-A-S-E-V-T-I-D-S-H-T-G-V-R-A-L-D-A-M-A-R-Y-G-K-V-A-G-H-P-A-A-L-N-L-G-D-C-F-A-Y-A-A-A-K-E-S-G-L-T-L-I-Y-K-G-N-D-F-S-Q-T-D-L-G


### FUNCTION Has lost one of the conserved residue  proposed to be part of the active site Therefore it could be inactive ### SEQUENCE -M-G-S-Y-T-I-P-N-V-V-E-R-T-P-Q-G-E-R-S-Y-D-V-F-S-R-L-L-S-E-R-I-I-F-L-G-T-E-I-D-D-G-V-A-N-V-V-I-A-Q-L-L-H-L-E-S-S-A-P-E-S-E-I-A-V-Y-I-N-S-P-G-G-S-F-T-S-L-M-A-I-Y-D-T-M-T-F-V-Q-A-P-I-S-T-F-C-V-G-Q-A-A-S-T-A-A-V-L-L-A-G-G-D-P-G-R-R-F-V-L-E-H-A-R-V-L-L-G-Q-P-A-S-G-G-R-Q-G-T-V-S-D-L-A-L-Q-A-K-E-M-V-R-I-R-S-Q-V-E-E-V-L-A-R-H-T-H-H-D-V-A-T-L-R-A-D-M-D-R-D-K-V-F-T-A-Q-E-A-V-A-Y-G-L-A-D-E-V-L-A-R-R-L-T-R-V


### FUNCTION Part of cytochrome c oxidase, its function is unknown ### SEQUENCE -M-K-I-Q-G-K-M-F-I-W-L-S-V-F-I-L-A-V-A-V-V-Y-G-Y-W-S-K-E-P-A-G-T-T-A-L-F-L-A-F-G-L-A-I-M-I-G-F-Y-L-A-F-T-A-R-R-V-D-A-G-A-Q-D-D-M-E-A-D-V-A-D-E-A-G-E-V-G-F-F-S-P-H-S-W-Q-P-L-S-L-A-V-G-G-A-L-A-F-L-G-I-A-V-G-W-W-V-M-Y-F-S-A-P-I-L-M-V-G-L-F-G-W-V-F-E-Y-Y-R-G-E-N-R-T-Q


### FUNCTION Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit ### SEQUENCE -M-P-R-P-R-K-A-D-R-T-P-A-R-Q-R-P-N-P-L-D-R-D-G-V-T-Y-V-D-Y-K-D-T-E-L-L-R-K-F-V-S-D-R-G-K-I-R-S-R-R-V-T-R-V-T-S-Q-Q-Q-R-Q-L-A-R-A-I-K-N-A-R-E-M-A-L-L-P-Y-G-T-R


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-K-S-K-I-A-K-N-E-Q-R-R-E-I-V-A-R-Y-A-A-R-R-A-E-L-K-E-V-L-R-R-P-S-S-T-E-A-E-R-L-A-A-Q-R-E-L-R-R-Q-P-R-D-A-S-P-T-R-V-R-N-R-D-Q-I-D-G-R-P-R-G-Y-L-R-V-F-G-L-S-R-V-N-L-R-E-Q-A-H-A-G-H-L-P-G-V-R-K-S-S-W


### FUNCTION Binds together with bS18 to 16S ribosomal RNA ### SEQUENCE -M-R-H-Y-E-V-M-V-I-L-D-P-D-L-E-E-R-S-V-S-P-L-I-E-N-F-L-S-V-V-R-D-G-G-G-K-V-E-K-V-D-T-W-G-R-R-R-L-S-Y-E-I-K-K-K-P-E-G-I-Y-S-V-I-D-L-Q-A-E-P-A-V-V-K-E-L-D-R-Q-M-N-L-N-E-S-V-L-R-T-K-V-L-R-P-E-M-H


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-I-I-L-T-H-E-V-S-G-L-G-A-A-G-D-V-V-D-V-K-D-G-Y-A-R-N-Y-L-I-P-R-K-F-A-I-R-W-T-K-G-G-E-K-D-V-E-Q-I-R-R-A-R-K-I-H-E-I-Q-T-I-E-Q-A-N-Q-V-K-A-Q-L-E-G-V-K-V-R-L-A-V-R-S-G-D-A-G-R-L-F-G-S-V-T-P-A-D-V-A-S-A-I-K-A-A-G-G-P-E-V-D-K-R-R-I-E-L-G-S-P-I-K-T-L-G-A-H-E-T-S-V-R-L-H-P-E-V-D-A-K-V-S-I-E-V-V-A-A


### FUNCTION Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-S-T-V-E-L-L-K-H-I-Y-D-I-N-L-S-Y-L-L-L-A-Q-R-L-I-N-H-E-K-A-S-A-M-F-R-L-G-I-S-E-S-M-A-D-T-L-A-E-L-T-L-P-Q-L-V-K-L-A-E-T-N-Q-L-I-C-H-F-R-F-E-D-H-E-T-V-Q-Q-L-T-K-E-S-R-V-D-D-L-Q-Q-I-H-T-G-I-L-L-S-T-H-L-F-Q-Q-L-S-A-Q-D-D-T-S-I-K-K-R-A


### FUNCTION Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes Also regulates genes whose products function in a variety of physiological pathways ### SEQUENCE -M-V-E-K-S-I-V-Q-E-A-K-D-I-Q-L-A-M-E-L-I-T-L-G-A-R-L-Q-M-L-E-S-E-T-Q-L-S-R-G-R-L-I-R-L-Y-K-E-L-R-G-S-P-P-P-K-G-M-L-P-F-S-T-D-W-F-M-T-W-E-Q-N-I-H-S-S-M-F-Y-N-A-Y-R-F-L-L-K-S-G-H-C-E-G-V-E-V-V-V-K-A-Y-R-L-Y-L-E-Q-C-P-P-G-N-N-G-D-A-P-I-L-A-L-T-R-A-W-T-L-V-R-F-V-D-S-G-M-L-Q-P-T-E-C-R-C-C-G-G-T-F-I-T-H-A-H-Q-P-V-N-S-F-V-C-S-L-C-Q-P-P-S-R-A-V-K-K-R-K-L-S-P-Q-P-A-D-T-N-S-Q-L-L-D-G-F-A-Q-K-A-M


### FUNCTION Binds to DNA and alters its conformation May be involved in regulation of gene expression, nucleoid organization and DNA protection ### SEQUENCE -M-I-P-G-G-G-Q-P-N-M-Q-Q-L-L-Q-Q-A-Q-K-M-Q-Q-D-L-A-K-A-Q-E-E-L-A-R-T-E-V-D-G-Q-A-G-G-G-L-V-K-A-T-V-T-G-S-G-E-L-R-G-L-V-I-D-P-K-A-V-D-P-E-D-T-E-T-L-A-D-L-V-V-A-A-V-Q-A-A-N-E-N-A-Q-N-L-Q-Q-Q-K-L-G-P-L-A-Q-G-M-G-G-G-G-S-G-I-P-G-L-P-F


### FUNCTION May play a role in DNA repair It seems to be involved in an RecBC-independent recombinational process of DNA repair It may act with RecF and RecO ### SEQUENCE -M-Y-E-G-V-V-Q-D-L-I-D-E-L-G-R-L-P-G-V-G-P-K-S-A-Q-R-I-A-F-H-I-L-Q-A-E-P-V-D-V-R-R-L-A-Q-A-L-M-E-V-K-A-K-V-R-F-C-A-T-C-G-N-V-A-Q-E-E-Q-C-N-I-C-R-D-T-R-R-D-P-S-V-I-C-V-V-E-E-P-K-D-V-V-A-I-E-R-T-R-E-F-R-G-R-Y-H-V-L-G-G-A-I-S-P-I-D-G-V-G-P-D-D-L-R-I-R-E-L-L-A-R-L-A-D-G-S-V-T-E-L-I-L-A-T-D-P-N-L-E-G-E-A-T-A-T-Y-L-A-R-M-I-K-P-M-G-L-K-V-T-R-L-A-S-G-L-P-V-G-G-D-L-E-Y-A-D-E-V-T-L-G-R-A-F-E-G-R-R-L-L-D-V


### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation ### SEQUENCE -M-A-N-K-Q-D-L-I-A-K-V-A-A-A-T-E-L-T-K-K-D-S-A-A-A-V-D-A-V-F-A-A-V-T-E-Y-L-S-K-G-E-K-V-Q-L-I-G-F-G-N-F-E-V-R-E-R-A-A-R-K-G-R-N-P-Q-T-G-K-E-T-K-I-A-A-S-K-V-P-A-F-K-A-G-K-A-L-K-D-A-V-K


### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation ### SEQUENCE -M-A-N-K-Q-D-L-I-A-K-V-A-E-A-T-E-L-T-K-K-D-S-A-A-A-V-D-A-V-F-S-A-V-S-S-Y-L-A-K-G-E-K-V-Q-L-I-G-F-G-N-F-E-V-R-E-R-A-A-R-K-G-R-N-P-Q-T-G-E-E-I-K-I-K-A-S-K-V-P-A-F-K-A-G-K-A-L-K-D-A-V-K


### FUNCTION Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation ### SEQUENCE -M-A-N-K-Q-D-L-I-A-K-V-A-E-A-T-E-L-T-K-K-D-S-A-A-A-V-D-T-V-F-S-S-I-E-G-F-L-S-K-G-E-K-V-Q-L-I-G-F-G-N-F-E-V-R-E-R-A-A-R-K-G-R-N-P-Q-T-G-A-E-I-K-I-A-A-S-K-V-P-A-F-K-A-G-K-A-L-K-D-A-V-K


### FUNCTION Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule Could be involved in hydrogenase-linked redox processes ### SEQUENCE -M-S-E-Q-A-V-E-N-T-V-L-D-R-F-E-C-R-S-C-G-Y-V-Y-E-P-E-K-G-D-S-K-H-D-I-A-P-E-T-P-F-A-E-L-P-I-N-W-R-C-P-V-C-T-A-K-K-A-A-F-S-N-I-G-P-A-G-T-A-S-G-F-R-E-N-L-G-Y-G-L-G-V-N-K-L-T-P-A-Q-K-N-I-L-I-F-G-A-L-A-L-G-F-L-F-F-I-S-L-Y-G-L-Q


### FUNCTION Together with the chaperonin GroEL, plays an essential role in assisting protein folding The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel ### SEQUENCE -M-A-K-V-K-I-K-P-L-S-D-R-V-V-I-K-P-E-P-P-E-E-K-T-E-S-G-L-Y-I-P-D-T-A-K-E-K-P-Q-R-G-T-V-I-A-V-G-P-G-R-V-E-N-G-T-K-I-E-M-S-V-K-E-G-D-K-V-L-Y-G-K-Y-A-G-T-E-I-T-I-D-G-E-E-Y-L-I-M-R-E-T-D-I-L-G-I-I-E-E-E-K


### FUNCTION Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate ### SEQUENCE -M-V-N-L-N-I-A-L-I-A-H-D-M-K-K-S-L-M-I-D-F-A-I-A-Y-K-D-I-L-E-K-C-N-I-Y-A-T-G-A-T-G-Q-L-V-E-E-A-T-G-I-K-V-N-K-F-L-P-G-P-M-G-G-D-Q-Q-I-G-A-M-I-A-E-D-K-M-D-L-V-I-F-L-R-D-P-L-T-A-Q-P-H-E-P-D-I-L-A-L-L-R-V-C-D-V-H-S-I-P-L-A-T-N-L-A-T-A-E-V-L-I-K-G-L-D-A-G-L-L-E-W-R-N-A-V-K


### FUNCTION Catalyzes the conversion of dTDP-4-amino-4,6-dideoxy-D-glucose ### SEQUENCE -M-A-Y-L-D-E-I-Q-L-K-E-M-G-F-K-S-V-G-E-N-V-K-I-S-D-K-A-S-F-Y-G-C-D-N-I-S-I-G-N-N-V-R-I-D-D-F-C-V-F-S-A-G-E-G-G-I-D-I-H-D-Y-I-H-I-A-V-Y-S-S-I-I-G-K-G-K-V-T-I-S-D-Y-A-N-I-S-S-R-V-S-I-Y-S-S-N-E-Y-Y-S-G-N-Y-M-S-N-P-V-V-P-S-E-Y-T-N-I-H-S-G-T-V-F-I-G-K-H-V-I-I-G-C-G-S-I-V-L-P-D-V-I-L-H-E-G-A-A-I-G-A-L-S-V-V-K-E-D-C-E-A-F-T-V-N-V-G-I-P-A-K-P-I-S-E-R-S-K-K-L-L-E-L-E-S-V-F-K-P-S-A-I-G-D-N-L


### FUNCTION Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA Forms part of the Shine-Dalgarno cleft in the 70S ribosome ### SEQUENCE -M-A-D-D-K-K-S-V-K-K-E-K-K-V-K-K-K-E-K-K-I-V-P-R-G-K-V-Y-I-T-A-S-F-N-N-T-I-V-T-I-T-D-M-A-G-N-T-I-S-W-S-T-S-G-A-M-G-F-R-G-S-K-K-S-T-P-Y-A-A-Q-I-A-A-G-N-A-A-E-K-A-M-D-S-A-G-L-Q-E-V-D-V-M-V-S-G-P-G-I-G-R-E-S-A-I-R-S-L-V-A-R-G-L-N-I-K-M-I-K-D-V-T-P-L-P-H-N-G-C-R-P-R-K-R-R-R-V


### FUNCTION Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA In the 70S ribosome it contacts the 23S rRNA , connecting the 2 subunits ### SEQUENCE -M-A-R-I-A-G-I-D-L-P-R-E-K-R-I-V-V-G-L-T-Y-I-F-G-I-G-N-S-L-S-K-L-I-L-K-K-A-G-I-D-E-S-I-R-V-K-D-L-N-E-S-Q-E-A-A-I-R-K-T-L-E-E-T-A-K-V-E-G-D-L-R-S-E-I-Q-L-N-I-K-R-L-M-D-I-G-C-Y-R-G-L-R-H-R-R-G-L-P-V-N-G-Q-R-T-R-T-N-A-R-T-R-K-G-G-K-K-T-V-A-N-K-K-K-V-T-K


### FUNCTION One of the essential components for the initiation of protein synthesis Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex ### SEQUENCE -M-A-K-E-E-A-I-T-V-D-G-T-V-L-E-P-L-P-N-A-M-F-R-V-E-L-E-N-G-H-K-V-L-A-H-I-S-G-K-M-R-M-H-Y-I-R-I-L-P-G-D-K-V-T-V-E-L-S-P-Y-D-L-S-K-G-R-I-T-Y-R-K-K


### FUNCTION Binds to the 23S rRNA ### SEQUENCE -M-K-K-E-R-L-E-Q-A-S-A-F-G-K-D-R-V-K-K-K-K-N-T-D-T-S-S-N-L-I-P-V-P-K-G-A-T-K-E-K-K-R-V-G-R-G-P-G-S-K-V-G-K-T-A-G-R-G-S-K-G-Q-Y-A-R-N-T-V-R-R-G-F-E-G-G-Q-M-P-I-H-R-R-L-P-K-R-G-F-T-S-K-F-H-K-E-F-Y-P-V-N-L-R-D-I-E-K-S-G-L-T-G-N-I-D-A-K-I-M-V-Q-S-K-I-L-D-K-E-T-T-L-F-K-I-L-G-T-G-E-I-K-K-A-I-H-V-I-A-D-G-F-S-Q-S-A-K-E-K-I-E-K-A-G-G-S-I-K-L-R-A-E-L-K-L-A-T-S-E-T-K-K


### FUNCTION With S4 and S12 plays an important role in translational accuracy ### SEQUENCE -M-A-Y-Q-D-E-E-S-K-E-Y-S-E-K-V-V-K-I-D-R-V-A-K-V-V-K-G-G-R-R-F-S-F-N-A-L-S-V-V-G-D-Q-R-G-K-V-G-I-G-F-G-K-A-N-E-V-P-D-A-I-R-K-S-I-E-S-A-K-K-H-L-V-K-I-N-F-K-G-H-T-I-P-H-E-V-I-G-K-F-K-S-A-R-V-I-L-K-P-S-T-A-G-T-G-I-I-A-G-A-S-V-R-S-I-V-E-K-A-G-I-Q-D-V-L-T-K-S-W-G-S-S-N-P-V-N-I-V-K-A-T-L-D-A-L-E-Q-L-E-T-P-I-L-A-A-K-K-R-G-I-S-L-N-K-L-F-G-K-D


### FUNCTION This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance ### SEQUENCE -M-I-D-R-L-K-K-S-I-S-K-T-K-R-A-E-R-S-R-F-K-L-K-K-L-G-S-R-P-R-L-V-F-I-K-S-N-Q-Y-L-S-C-Q-I-I-D-D-I-Q-G-V-T-L-A-Y-A-T-T-S-E-K-T-F-T-G-E-G-K-S-K-K-D-K-G-A-A-K-V-L-G-K-L-I-A-E-R-G-S-Q-K-G-V-K-Q-V-M-L-D-R-S-G-M-I-F-H-G-R-I-A-A-F-A-E-G-A-R-E-A-G-L-E-F


### FUNCTION This protein binds to the 23S rRNA, and is important in its secondary structure It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center ### SEQUENCE -M-S-R-I-G-K-A-E-I-K-L-P-D-K-V-E-V-K-Q-E-N-A-N-I-K-V-K-G-P-L-G-E-L-F-T-P-I-F-E-G-I-S-V-K-T-E-N-G-I-V-K-L-E-R-S-N-E-D-Q-K-V-V-A-L-H-G-L-T-R-A-L-L-M-N-C-V-K-G-V-S-Q-G-W-E-K-N-L-E-I-T-G-V-G-Y-R-A-Q-K-R-G-E-D-L-V-M-S-L-G-F-S-H-E-V-V-Y-K-A-P-K-G-I-K-I-D-V-Q-E-Q-L-K-I-K-V-S-G-I-D-K-Q-L-V-G-Q-V-A-A-D-I-R-S-K-R-P-P-E-P-Y-K-G-K-G-I-K-Y-A-E-E-F-I-K-K-K-A-G-K-T-G-K-K


### FUNCTION One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit ### SEQUENCE -M-S-M-S-D-P-I-G-D-M-L-T-R-I-R-N-A-G-R-A-K-H-E-T-C-L-V-P-G-S-K-I-K-K-S-I-L-D-L-M-K-E-E-G-F-I-K-D-Y-E-S-V-K-V-N-E-T-F-E-D-Y-K-V-F-L-K-Y-D-H-T-K-R-P-I-I-R-E-L-V-R-V-S-T-P-G-R-R-V-Y-I-K-S-A-E-I-R-P-Y-K-N-N-I-G-T-L-I-V-S-T-S-K-G-I-M-T-G-K-N-A-R-K-L-K-L-G-G-E-V-I-L-K-M-S


### FUNCTION Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site ### SEQUENCE -M-A-K-T-S-I-T-V-R-H-Q-R-K-K-K-F-E-V-R-E-Y-N-R-C-P-I-C-G-R-S-R-G-Y-L-R-R-F-D-M-C-R-I-C-F-R-K-L-A-S-G-A-Q-I-P-G-V-V-K-S-S-W


### FUNCTION This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance In the 70S ribosome it contacts protein S13 of the 30S subunit , connecting the 2 subunits ### SEQUENCE -M-A-A-R-L-R-T-K-Y-K-K-E-I-V-P-E-L-N-K-K-F-K-F-S-S-I-M-Q-V-P-R-L-E-K-I-V-L-N-V-G-M-G-E-A-H-T-N-P-K-A-L-E-A-A-V-E-E-L-A-L-I-T-G-Q-R-P-V-K-T-K-A-K-K-S-I-A-G-F-K-I-R-E-G-M-S-L-G-C-M-V-T-L-R-G-D-Y-M-Y-E-F-L-D-R-L-V-N-V-A-L-P-R-V-R-D-F-K-G-V-S-E-K-G-F-D-G-R-G-N-Y-N-M-S-I-K-E-Q-I-I-F-P-E-I-K-V-D-K-I-N-T-L-Y-G-I-N-M-T-F-V-T-N-S-K-S-N-E-E-A-Y-S-L-L-A-A-F-G-M-P-Y-R-N-Q-K


### FUNCTION One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit ### SEQUENCE -M-A-K-L-T-Y-R-G-S-E-Y-T-K-F-K-K-F-R-I-K-K-N-D-E-V-I-C-I-T-G-K-H-K-G-K-R-G-K-V-L-S-I-D-K-K-R-D-R-V-I-V-E-G-L-N-K-R-K-R-F-M-R-P-T-Q-E-N-P-Q-G-G-V-I-E-V-E-A-P-I-H-I-S-N-V-M-F-Y-D-P-K-K-K-K-K-A-G-V-R-V-G-F-E-T-V-K-G-K-K-V-R-V-S-R-P-D-K-K-E-L


### FUNCTION Binds to 23S rRNA Forms part of two intersubunit bridges in the 70S ribosome ### SEQUENCE -M-I-Q-Q-E-T-L-L-Q-V-A-D-N-S-G-I-K-K-V-M-C-I-K-V-L-G-G-S-K-K-R-Y-A-S-V-G-D-E-I-I-V-A-V-K-D-A-Q-P-A-F-G-L-K-D-S-T-G-K-K-V-H-N-K-A-V-Q-R-A-V-V-V-R-T-T-K-E-I-R-R-P-D-G-S-Y-I-R-F-D-D-N-A-C-A-I-I-D-D-K-G-N-P-K-G-T-R-I-F-G-P-V-A-R-E-L-R-D-K-K-Y-A-K-I-I-S-L-A-P-E-V-L


### FUNCTION One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA ### SEQUENCE -M-T-A-G-K-Q-H-I-N-K-S-L-L-Y-E-G-R-V-V-S-N-S-M-N-K-T-V-V-I-L-V-E-T-R-K-T-H-P-K-F-K-K-I-V-R-R-S-V-R-L-K-V-H-D-E-K-N-E-C-V-V-G-D-K-I-L-A-I-E-T-R-P-L-S-K-E-K-R-H-R-L-Y-K-I-V-E-K-A-K


### FUNCTION Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs ### SEQUENCE -M-L-S-P-K-R-V-K-F-R-K-R-Q-R-G-R-L-K-G-T-D-E-R-G-S-S-V-S-F-G-E-F-G-L-K-A-V-T-S-G-R-L-T-A-R-Q-I-E-A-A-R-I-T-I-N-R-Q-V-K-R-G-G-K-L-W-I-R-I-F-P-H-T-P-I-T-K-K-P-A-E-T-R-M-G-K-G-K-G-N-P-E-F-W-I-A-E-I-R-P-G-R-I-L-F-E-M-S-G-I-D-E-E-T-A-K-K-A-L-S-L-A-S-Y-K-L-P-I-H-T-E-F-V-K-R-S-A-L


### FUNCTION This protein binds specifically to 23S rRNA ### SEQUENCE -M-E-A-K-A-V-S-R-F-V-R-M-S-P-R-K-V-R-L-V-A-D-E-I-R-G-Y-A-V-N-E-A-L-D-I-L-K-F-T-N-K-R-A-I-E-P-L-T-K-V-I-L-S-A-S-A-N-A-S-V-L-N-N-K-V-D-F-N-Q-L-F-I-K-K-I-Y-V-D-E-G-P-I-M-K-R-F-R-P-R-A-R-G-R-A-A-R-I-R-K-R-L-S-H-I-T-V-V-L-S-D


### FUNCTION Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA ### SEQUENCE -M-A-R-S-V-K-K-G-P-F-I-D-D-H-L-M-K-K-I-T-K-L-N-S-E-N-Q-K-K-P-F-K-T-W-S-R-R-S-T-I-F-P-D-M-V-G-H-T-V-M-V-H-N-G-K-Q-F-T-P-V-Y-I-N-E-N-M-I-G-H-K-L-G-E-F-S-P-T-R-T-F-R-G-H-V-A-G-D-K-K-A-A-K-K


### FUNCTION One of the early assembly proteins it binds 23S rRNA One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome Forms the main docking site for trigger factor binding to the ribosome ### SEQUENCE -M-N-L-Q-D-V-I-L-T-P-I-V-T-E-K-S-Q-D-L-E-T-I-G-A-N-S-K-K-G-T-R-M-V-K-Y-T-V-K-V-H-I-D-A-N-K-T-L-I-K-E-A-F-K-K-I-F-K-V-T-P-S-S-V-N-V-Q-V-Y-R-G-K-I-K-R-F-R-N-M-P-A-A-R-P-H-W-K-K-A-I-V-T-F-R-D-G-A-S-I-D-F-A-K-E-A


### FUNCTION Involved in the binding of tRNA to the ribosomes ### SEQUENCE -M-A-G-Q-K-I-R-V-K-L-K-A-F-D-H-R-L-I-D-Q-S-T-Y-E-I-V-A-T-A-K-R-T-G-A-T-V-S-G-P-I-P-L-P-T-K-K-E-I-Y-T-V-L-R-S-P-H-V-N-K-K-S-R-E-Q-F-E-L-K-T-H-K-R-L-I-D-I-L-D-T-N-E-D-T-V-E-A-L-M-K-L-Q-L-P-A-G-V-S-V-D-I-K-S


### FUNCTION Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis ### SEQUENCE -M-N-A-K-T-L-D-A-I-K-P-F-L-D-W-I-P-L-I-V-F-F-Y-I-Y-K-T-T-E-G-E-G-S-E-H-I-I-A-A-T-T-G-L-L-I-A-T-L-I-V-Y-G-L-M-F-V-L-Q-K-F-T-L-E-K-R-Q-W-L-V-V-V-L-T-V-V-F-G-G-L-T-M-A-F-Q-D-D-F-Y-I-R-L-K-A-P-I-I-N-A-V-F-A-F-G-L-A-M-S-P-L-F-L-G-G-T-P-G-I-Q-K-M-L-G-P-I-F-E-M-T-P-K-Q-W-M-K-L-N-W-V-W-V-G-F-F-T-L-M-A-V-L-Q-A-L-F-A-F-V-W-V-E-Y-W-A-M-F-T-A-F-G-D-M-I-V-M-V-V-F-M-V-A-Q-F-W-F-L-R-G-F-M-R-K-D-I-K


### FUNCTION Probably involved in ribonucleotide reductase function ### SEQUENCE -M-L-I-V-Y-F-S-S-A-T-D-N-T-H-R-F-V-Q-K-L-D-L-P-N-V-R-I-P-L-T-R-V-E-E-P-L-K-I-N-E-P-Y-V-L-I-T-P-T-Y-G-G-G-V-S-M-T-G-E-N-S-R-P-V-P-P-Q-V-I-R-F-L-N-D-E-H-N-R-S-F-I-R-A-V-V-A-G-G-N-S-N-F-G-S-D-F-G-L-A-G-E-I-I-S-K-K-C-K-V-P-Y-V-Y-R-F-E-L-M-G-N-E-E-D-V-S-I-L-R-G-G-L-T-Q-N-A-Q-A-L-G-L-E-P-Q-E-P-V-T-S-R