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refresh the 4 clinical tables to the 11-trait build, evidence_as_of unchanged at 2026-07-24
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refresh 7 unmanifested atlas tables to the current development build (11 traits, macaque, current population vocabulary, pinned MDD study)
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refresh open_targets_genetics_trait_coverage to 11 traits (was missing fibromyalgia)
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mirror Open Targets 26.06 evidence_clinical_precedence for the weekly clinical refresh
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mirror Open Targets 26.06 drug_molecule for the weekly clinical refresh
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publish the fda atlas v2 release rebuilt on the unified scdrs recipe
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update browser scdrs scores to the unified sct + mean_var + donor covariate recipe
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remove legacy provenance-ambiguous samap artifacts
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remove legacy provenance-ambiguous samap artifacts
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rebuild correspondence on shipped atlas f4edb55a (22871x25037)
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rebuild correspondence on shipped atlas f4edb55a (22871x25037)
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Option B scDRS scores, 11 traits (adds fibromyalgia)
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scdrs: 11 traits on SCT corrected counts, pooled scoring, seed 42
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add sox6_nonanxa scdrs population effects (+20 rows) and refresh manifest
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color_ui: drop duplicate 'Integrated clusters' (integrated_leiden)
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hover: rename Consensus subtype -> Integrated subtype
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3d paga: paga-graph-seeded embeddings, bypass scanpy init rescaling (66023ed)
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add recorded correspondence and rhesus conservation
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refresh clinical concordance evidence
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publish clinical concordance tables
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publish validated fda atlas release
Elan Schonfeld
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publish corrected human browser atlas
Elan Schonfeld
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human brain-wide axis: all 11 DA donors vs shared DA-free WHB reference (matches mouse estimator; kamath no longer dropped)
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add slim cross-species conservation labels (511 genes incl 7 paralog-pooled)
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Add fda_atlas_v2 release (41 tables) for the FDA Drug Target Atlas tab
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document fda disease atlas release
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add comprehensive fda disease atlas release
Adds the 1,715-target human and mouse FDA x scDRS atlas, regulatory product and substance-target tables, manifest, and data dictionary.
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kamath PAGA-2D: distinct paga-init layout on LIGER reduction (default-2D stays canonical)
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restore Gad2 HMoE labels for Siletti (keep_gad2=True): 257 cells -> Gad2:Egfr/Gad2:Ebf2
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fix: preserve uns color_ui + method_switch in slim (restore finalized Color-by menu + scCRAFT/scVI/RPCA)
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refresh alra_factors.npz: rebuilt Kamath+Siletti atlas (22871x25037, slim)
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refresh human_da_browser.h5ad: rebuilt Kamath+Siletti atlas (22871x25037, slim)
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add 3d brain artifact (WiP): projection_brain.npz
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add 3d brain artifact (WiP): brain_shell_mesh.json
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add 3d brain artifact (WiP): vep_mesh.json
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add 3d brain artifact (WiP): nac_mesh.json
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add 3d brain artifact (WiP): putamen_mesh.json
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add 3d brain artifact (WiP): caudate_mesh.json
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add projection/FDA data (WiP): fda_occupancy.csv
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add projection/FDA data (WiP): fda_drugs.csv
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add projection/FDA data (WiP): fda_receptors.csv
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add projection/FDA data (WiP): projection_spatial_cells.parquet
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add projection/FDA data (WiP): projection_spatial_voxels.parquet
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add projection/FDA data (WiP): projection_broadregion_subtypes.tsv
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add projection/FDA data (WiP): projection_broadregion_families.tsv
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update human_da_browser.h5ad (scdrs scores + samap)
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update samap_links.csv (scdrs scores + samap)
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update samap_scores.csv (scdrs scores + samap)
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add canonical ALRA factors (rank 53)
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standardize subtype names (Family:Subtype, merge shared)
