# Copyright (c) MONAI Consortium # Licensed under the Apache License, Version 2.0 (the "License"); # you may not use this file except in compliance with the License. # You may obtain a copy of the License at # http://www.apache.org/licenses/LICENSE-2.0 # Unless required by applicable law or agreed to in writing, software # distributed under the License is distributed on an "AS IS" BASIS, # WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. # See the License for the specific language governing permissions and # limitations under the License. """Transforms using a smooth spatial field generated by interpolating from smaller randomized fields.""" from __future__ import annotations from collections.abc import Sequence from typing import Any import numpy as np import torch from torch.nn.functional import grid_sample, interpolate from monai.config.type_definitions import NdarrayOrTensor from monai.data.meta_obj import get_track_meta from monai.networks.utils import meshgrid_ij from monai.transforms.transform import Randomizable, RandomizableTransform from monai.transforms.utils_pytorch_numpy_unification import moveaxis from monai.utils import GridSampleMode, GridSamplePadMode, InterpolateMode from monai.utils.enums import TransformBackends from monai.utils.module import look_up_option from monai.utils.type_conversion import convert_to_dst_type, convert_to_tensor __all__ = ["SmoothField", "RandSmoothFieldAdjustContrast", "RandSmoothFieldAdjustIntensity", "RandSmoothDeform"] class SmoothField(Randomizable): """ Generate a smooth field array by defining a smaller randomized field and then reinterpolating to the desired size. This exploits interpolation to create a smoothly varying field used for other applications. An initial randomized field is defined with `rand_size` dimensions with `pad` number of values padding it along each dimension using `pad_val` as the value. If `spatial_size` is given this is interpolated to that size, otherwise if None the random array is produced uninterpolated. The output is always a Pytorch tensor allocated on the specified device. Args: rand_size: size of the randomized field to start from pad: number of pixels/voxels along the edges of the field to pad with `pad_val` pad_val: value with which to pad field edges low: low value for randomized field high: high value for randomized field channels: number of channels of final output spatial_size: final output size of the array, None to produce original uninterpolated field mode: interpolation mode for resizing the field align_corners: if True align the corners when upsampling field device: Pytorch device to define field on """ backend = [TransformBackends.TORCH] def __init__( self, rand_size: Sequence[int], pad: int = 0, pad_val: float = 0, low: float = -1.0, high: float = 1.0, channels: int = 1, spatial_size: Sequence[int] | None = None, mode: str = InterpolateMode.AREA, align_corners: bool | None = None, device: torch.device | None = None, ): self.rand_size = tuple(rand_size) self.pad = pad self.low = low self.high = high self.channels = channels self.mode = mode self.align_corners = align_corners self.device = device self.spatial_size: Sequence[int] | None = None self.spatial_zoom: Sequence[float] | None = None if low >= high: raise ValueError("Value for `low` must be less than `high` otherwise field will be zeros") self.total_rand_size = tuple(rs + self.pad * 2 for rs in self.rand_size) self.field = torch.ones((1, self.channels) + self.total_rand_size, device=self.device) * pad_val self.crand_size = (self.channels,) + self.rand_size pad_slice = slice(None) if self.pad == 0 else slice(self.pad, -self.pad) self.rand_slices = (0, slice(None)) + (pad_slice,) * len(self.rand_size) self.set_spatial_size(spatial_size) def randomize(self, data: Any | None = None) -> None: self.field[self.rand_slices] = torch.from_numpy(self.R.uniform(self.low, self.high, self.crand_size)) # type: ignore[index] def set_spatial_size(self, spatial_size: Sequence[int] | None) -> None: """ Set the `spatial_size` and `spatial_zoom` attributes used for interpolating the field to the given dimension, or not interpolate at all if None. Args: spatial_size: new size to interpolate to, or None to not interpolate """ if spatial_size is None: self.spatial_size = None self.spatial_zoom = None else: self.spatial_size = tuple(spatial_size) self.spatial_zoom = tuple(s / f for s, f in zip(self.spatial_size, self.total_rand_size)) def set_mode(self, mode: str) -> None: self.mode = mode def __call__(self, randomize=False) -> torch.Tensor: if randomize: self.randomize() field = self.field.clone() if self.spatial_zoom is not None: resized_field = interpolate( input=field, scale_factor=self.spatial_zoom, mode=look_up_option(self.mode, InterpolateMode), align_corners=self.align_corners, recompute_scale_factor=False, ) mina = resized_field.min() maxa = resized_field.max() minv = self.field.min() maxv = self.field.max() # faster than rescale_array, this uses in-place operations and doesn't perform unneeded range checks norm_field = (resized_field.squeeze(0) - mina).div_(maxa - mina) field = norm_field.mul_(maxv - minv).add_(minv) return field class RandSmoothFieldAdjustContrast(RandomizableTransform): """ Randomly adjust the contrast of input images by calculating a randomized smooth field for each invocation. This uses SmoothField internally to define the adjustment over the image. If `pad` is greater than 0 the edges of the input volume of that width will be mostly unchanged. Contrast is changed by raising input values by the power of the smooth field so the range of values given by `gamma` should be chosen with this in mind. For example, a minimum value of 0 in `gamma` will produce white areas so this should be avoided. After the contrast is adjusted the values of the result are rescaled to the range of the original input. Args: spatial_size: size of input array's spatial dimensions rand_size: size of the randomized field to start from pad: number of pixels/voxels along the edges of the field to pad with 1 mode: interpolation mode to use when upsampling align_corners: if True align the corners when upsampling field prob: probability transform is applied gamma: (min, max) range for exponential field device: Pytorch device to define field on """ backend = [TransformBackends.TORCH] def __init__( self, spatial_size: Sequence[int], rand_size: Sequence[int], pad: int = 0, mode: str = InterpolateMode.AREA, align_corners: bool | None = None, prob: float = 0.1, gamma: Sequence[float] | float = (0.5, 4.5), device: torch.device | None = None, ): super().__init__(prob) if isinstance(gamma, (int, float)): self.gamma = (0.5, gamma) else: if len(gamma) != 2: raise ValueError("Argument `gamma` should be a number or pair of numbers.") self.gamma = (min(gamma), max(gamma)) self.sfield = SmoothField( rand_size=rand_size, pad=pad, pad_val=1, low=self.gamma[0], high=self.gamma[1], channels=1, spatial_size=spatial_size, mode=mode, align_corners=align_corners, device=device, ) def set_random_state( self, seed: int | None = None, state: np.random.RandomState | None = None ) -> RandSmoothFieldAdjustContrast: super().set_random_state(seed, state) self.sfield.set_random_state(seed, state) return self def randomize(self, data: Any | None = None) -> None: super().randomize(None) if self._do_transform: self.sfield.randomize() def set_mode(self, mode: str) -> None: self.sfield.set_mode(mode) def __call__(self, img: NdarrayOrTensor, randomize: bool = True) -> NdarrayOrTensor: """ Apply the transform to `img`, if `randomize` randomizing the smooth field otherwise reusing the previous. """ img = convert_to_tensor(img, track_meta=get_track_meta()) if randomize: self.randomize() if not self._do_transform: return img img_min = img.min() img_max = img.max() img_rng = img_max - img_min field = self.sfield() rfield, *_ = convert_to_dst_type(field, img) # everything below here is to be computed using the destination type (numpy, tensor, etc.) img = (img - img_min) / (img_rng + 1e-10) # rescale to unit values img = img**rfield # contrast is changed by raising image data to a power, in this case the field out = (img * img_rng) + img_min # rescale back to the original image value range return out class RandSmoothFieldAdjustIntensity(RandomizableTransform): """ Randomly adjust the intensity of input images by calculating a randomized smooth field for each invocation. This uses SmoothField internally to define the adjustment over the image. If `pad` is greater than 0 the edges of the input volume of that width will be mostly unchanged. Intensity is changed by multiplying the inputs by the smooth field, so the values of `gamma` should be chosen with this in mind. The default values of `(0.1, 1.0)` are sensible in that values will not be zeroed out by the field nor multiplied greater than the original value range. Args: spatial_size: size of input array rand_size: size of the randomized field to start from pad: number of pixels/voxels along the edges of the field to pad with 1 mode: interpolation mode to use when upsampling align_corners: if True align the corners when upsampling field prob: probability transform is applied gamma: (min, max) range of intensity multipliers device: Pytorch device to define field on """ backend = [TransformBackends.TORCH] def __init__( self, spatial_size: Sequence[int], rand_size: Sequence[int], pad: int = 0, mode: str = InterpolateMode.AREA, align_corners: bool | None = None, prob: float = 0.1, gamma: Sequence[float] | float = (0.1, 1.0), device: torch.device | None = None, ): super().__init__(prob) if isinstance(gamma, (int, float)): self.gamma = (0.5, gamma) else: if len(gamma) != 2: raise ValueError("Argument `gamma` should be a number or pair of numbers.") self.gamma = (min(gamma), max(gamma)) self.sfield = SmoothField( rand_size=rand_size, pad=pad, pad_val=1, low=self.gamma[0], high=self.gamma[1], channels=1, spatial_size=spatial_size, mode=mode, align_corners=align_corners, device=device, ) def set_random_state( self, seed: int | None = None, state: np.random.RandomState | None = None ) -> RandSmoothFieldAdjustIntensity: super().set_random_state(seed, state) self.sfield.set_random_state(seed, state) return self def randomize(self, data: Any | None = None) -> None: super().randomize(None) if self._do_transform: self.sfield.randomize() def set_mode(self, mode: str) -> None: self.sfield.set_mode(mode) def __call__(self, img: NdarrayOrTensor, randomize: bool = True) -> NdarrayOrTensor: """ Apply the transform to `img`, if `randomize` randomizing the smooth field otherwise reusing the previous. """ img = convert_to_tensor(img, track_meta=get_track_meta()) if randomize: self.randomize() if not self._do_transform: return img field = self.sfield() rfield, *_ = convert_to_dst_type(field, img) # everything below here is to be computed using the destination type (numpy, tensor, etc.) out = img * rfield return out class RandSmoothDeform(RandomizableTransform): """ Deform an image using a random smooth field and Pytorch's grid_sample. The amount of deformation is given by `def_range` in fractions of the size of the image. The size of each dimension of the input image is always defined as 2 regardless of actual image voxel dimensions, that is the coordinates in every dimension range from -1 to 1. A value of 0.1 means pixels/voxels can be moved by up to 5% of the image's size. Args: spatial_size: input array size to which deformation grid is interpolated rand_size: size of the randomized field to start from pad: number of pixels/voxels along the edges of the field to pad with 0 field_mode: interpolation mode to use when upsampling the deformation field align_corners: if True align the corners when upsampling field prob: probability transform is applied def_range: value of the deformation range in image size fractions, single min/max value or min/max pair grid_dtype: type for the deformation grid calculated from the field grid_mode: interpolation mode used for sampling input using deformation grid grid_padding_mode: padding mode used for sampling input using deformation grid grid_align_corners: if True align the corners when sampling the deformation grid device: Pytorch device to define field on """ backend = [TransformBackends.TORCH] def __init__( self, spatial_size: Sequence[int], rand_size: Sequence[int], pad: int = 0, field_mode: str = InterpolateMode.AREA, align_corners: bool | None = None, prob: float = 0.1, def_range: Sequence[float] | float = 1.0, grid_dtype=torch.float32, grid_mode: str = GridSampleMode.NEAREST, grid_padding_mode: str = GridSamplePadMode.BORDER, grid_align_corners: bool | None = False, device: torch.device | None = None, ): super().__init__(prob) self.grid_dtype = grid_dtype self.grid_mode = grid_mode self.def_range = def_range self.device = device self.grid_align_corners = grid_align_corners self.grid_padding_mode = grid_padding_mode if isinstance(def_range, (int, float)): self.def_range = (-def_range, def_range) else: if len(def_range) != 2: raise ValueError("Argument `def_range` should be a number or pair of numbers.") self.def_range = (min(def_range), max(def_range)) self.sfield = SmoothField( spatial_size=spatial_size, rand_size=rand_size, pad=pad, low=self.def_range[0], high=self.def_range[1], channels=len(rand_size), mode=field_mode, align_corners=align_corners, device=device, ) grid_space = tuple(spatial_size) if spatial_size is not None else self.sfield.field.shape[2:] grid_ranges = [torch.linspace(-1, 1, d) for d in grid_space] grid = meshgrid_ij(*grid_ranges) self.grid = torch.stack(grid).unsqueeze(0).to(self.device, self.grid_dtype) def set_random_state(self, seed: int | None = None, state: np.random.RandomState | None = None) -> Randomizable: super().set_random_state(seed, state) self.sfield.set_random_state(seed, state) return self def randomize(self, data: Any | None = None) -> None: super().randomize(None) if self._do_transform: self.sfield.randomize() def set_field_mode(self, mode: str) -> None: self.sfield.set_mode(mode) def set_grid_mode(self, mode: str) -> None: self.grid_mode = mode def __call__( self, img: NdarrayOrTensor, randomize: bool = True, device: torch.device | None = None ) -> NdarrayOrTensor: img = convert_to_tensor(img, track_meta=get_track_meta()) if randomize: self.randomize() if not self._do_transform: return img device = device if device is not None else self.device field = self.sfield() dgrid = self.grid + field.to(self.grid_dtype) dgrid = moveaxis(dgrid, 1, -1) # type: ignore dgrid = dgrid[..., list(range(dgrid.shape[-1] - 1, -1, -1))] # invert order of coordinates img_t = convert_to_tensor(img[None], torch.float32, device) out = grid_sample( input=img_t, grid=dgrid, mode=look_up_option(self.grid_mode, GridSampleMode), align_corners=self.grid_align_corners, padding_mode=look_up_option(self.grid_padding_mode, GridSamplePadMode), ) out_t, *_ = convert_to_dst_type(out.squeeze(0), img) return out_t