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eval_wt_vs_kd_edit_tight_7cell_20260505/wt_vs_kd_summary.md
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# WT vs KD eval — n=700
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## Aggregate (all rows)
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- mean WT → KD : 0.303 → 0.266
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- KD/WT ratio : 0.877 (lower = stronger response)
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- KD<WT (depleted) : 68/700 (9.7%)
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- KD=WT (no change) : 589/700 (84.1%)
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- KD>WT (counter) : 43/700 (6.1%)
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## Conditional on rows with WT motif count > 0 (informative subset)
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- n informative : 169/700 (24.1%)
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- mean WT → KD : 1.254 → 0.876
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- conditional KD/WT : 0.698
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- KD<WT (depleted) : 68/169 (40.2%)
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## Per cell type
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| Cell | n | WT → KD | KD/WT | n_inf | inf KD/WT | inf depl. |
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|---|---:|---:|---:|---:|---:|---:|
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| Ast | 100 | 0.350 → 0.250 | 0.714 | 26 | 0.571 | 58% |
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| End | 100 | 0.170 → 0.170 | 1.000 | 14 | 0.765 | 29% |
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| Ex | 100 | 0.250 → 0.210 | 0.840 | 23 | 0.720 | 26% |
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| In | 100 | 0.480 → 0.420 | 0.875 | 35 | 0.750 | 37% |
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| Mic | 100 | 0.440 → 0.430 | 0.977 | 33 | 0.750 | 42% |
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| OPC | 100 | 0.240 → 0.160 | 0.667 | 21 | 0.583 | 48% |
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| Oli | 100 | 0.190 → 0.220 | 1.158 | 17 | 0.737 | 35% |
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