DeepStream: Autoencoder-Based Stream Temporal Clustering Shimon Harush, Yair Meidan, Asaf Shabtai Department of Software and Information Systems Engineering Ben-Gurion University of the Negev hshimo@post.bgu.ac.il,yairme@post.bgu.ac.il,shabtaia@bgu.ac.il ABSTRACT This paper presents DeepStream, a novel data stream temporal clustering algorithm that dynamically detects sequential and over- lapping clusters. DeepStream is tuned to classify contextual infor- mation in real time and is capable of coping with a high-dimensional feature space. DeepStream utilizes stacked autoencoders to reduce the dimensionality of unbounded data streams and for cluster rep- resentation. This method detects contextual behavior and captures nonlinear relations of the input data, giving it an advantage over existing methods that rely on PCA. We evaluated DeepStream em- pirically using four sensor and IoT datasets and compared it to five state-of-the-art stream clustering algorithms. Our evaluation shows that DeepStream outperforms all of these algorithms. CCS CONCEPTS • Computing methodologies →Machine learning algorithms; KEYWORDS Stream clustering; Autoencoder; Dimensionality reduction; Anom- aly detection ACM Reference Format: Shimon Harush, Yair Meidan, Asaf Shabtai. 2021. DeepStream: Autoencoder- Based Stream Temporal Clustering. In The 36th ACM/SIGAPP Symposium on Applied Computing (SAC ’21), March 22–26, 2021, Virtual Event, Republic of Korea. ACM, New York, NY, USA, Article 4, 4 pages. https://doi.org/10. 1145/3412841.3442083 1 INTRODUCTION Data stream clustering is a special type of clustering that has re- cently received increased attention from researchers motivated by the challenges posed by applications involving large datasets and streams of data, and the need to learn tasks in real time [1]. Several stream clustering algorithms have been proposed, most of which have two phases: an online phase, which summarizes the data into many micro-clusters, and an offline phase, in which these micro-clusters are re-clustered into a smaller number of final clus- ters [3]. However, none of these algorithms is suitable for clustering contextual sensor streams since these algorithms are designed to produce clusters that are agnostic to the order of arriving records. In contrast, the pcStream algorithm [19] is capable of capturing the temporal importance of the incoming data. Permission to make digital or hard copies of part or all of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for third-party components of this work must be honored. For all other uses, contact the owner/author(s). SAC ’21, March 22–26, 2021, Virtual Event, Republic of Korea © 2021 Copyright held by the owner/author(s). ACM ISBN 978-1-4503-8104-8/21/03. https://doi.org/10.1145/3412841.3442083 We propose a stream clustering method called DeepStream, which is designed to address the above mentioned limitations of existing stream clustering algorithms. DeepStream leverages deep learning techniques to capture the nonlinear relations of input data by using the embedded representation output of a pretrained stacked autoencoder (SAE). By integrating an SAE into the tempo- ral stream clustering algorithm, our method aims to improve the ability to cluster such data streams, thereby improving the quality of the clusters and is able to deal better with high-dimensional data streams. We evaluated our proposed method using four different datasets and compared its performance with that of five existing stream clustering algorithms. The results show a significant im- provement in clustering capabilities. Summary of contributions. a) We propose a stream cluster- ing algorithm which is capable of capturing temporal contexts. As a result of integrating SAEs, our method is able to (1) capture non- linear relations betwee


The OABN is a free, open network for anyone interested in OA books Sharing knowledge about OA books and building a community https://openaccessbooksnetwork.hcommons.org/ From Zero to One Hundred: Open Access Books Network (OABN) and community-based learning


High-throughput phenotypic profiling to inform putative mode of action for environmental chemicals Johanna Nyffeler1,2, Clinton Willis1, Grace Patlewicz1, Imran Shah1, Joshua Harrill1 1 Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Durham, NC 27711, United States. 2 Oak Ridge Institute for Science and Education (ORISE) Postdoctoral Fellow, Oak Ridge, TN, 37831, United States. INTRODUCTION & OBJECTIVE • US EPA has a tiered testing strategy for chemical hazard evaluation • High-throughput phenotypic profiling (HTPP) is an imaging based, untargeted screening approach • Can HTPP provide information about putative modes of action (MoA) as part of US EPA’s tiered testing strategy? APPROACH 1. Test 120 chemicals with annotated MoA and 441 environmental chemicals 2. Compute biological similarities of the phenotypic profiles and compare among chemicals MAIN RESULTS • Different phenotypic profiles are observed • Structurally similar chemicals often induce similar profiles • Structurally diverse chemicals with shared MoA often induce similar profiles IMPACT HTPP can be used to derive putative MoA information – both for structurally similar and structurally diverse chemicals - that could be used in the context of a tiered testing strategy for chemical hazard evaluation Abstract #320 Nyffeler.Johanna@epa.gov ORCiD 0000-0002-6155-9743 This work does not reflect US EPA policy. Mention of tradenames or products does not represent endorsement for use.


AMERICAN JOURNAL OF EDUCATION AND LEARNING ISSN: 2996-5128 (online) | ResearchBib (IF) = 9.918 IMPACT FACTOR Volume-2| Issue-5| 2024 Published: |30-12-2024| 781 BOSHLANG‘ICH SINF DARSLARINI INTEGRATSIYALASHGAN HOLDA TASHKIL ETISHNING AHAMIYATI. https://doi.org/10.5281/zenodo.14516261 Davlatova Sevara Normamat qizi Termiz iqtisodiyot va servis universiteti ta’lim tarbiya nazariyasi va metodikasi (boshlang‘ich ta’lim) 1- bosqich magistranti Annotatsiya Ushbu maqolada boshlang„ich sinf darslarini integratsiyalashgan holda tashkil etishning ahamiyati, ayrim talab va shartlari yoritilgan, integratsion darslarning umumiy xususiyatlari atroflicha bayon etilgan. Shuningdek, integratsion darslarning umumiy mundarijasidan kelib chiqqan holda, bu turdagi dars loyihasiga doir mashg„ulotlar strukturasi hamda integratsion texnologiyani tasniflangan. Kalit So‘Zlar integratsion, kompetentlik, klassifikatsiya, xarakterli, texnokratik, noan‟anaviy, ko„rgazma, faktor. Аннотатция В данной статье подчеркивается важность организации элементарных занятий интегрированным способом, выделяются некоторые требования и условия, подробно описываются общие особенности интегрированных занятий. Также на основе общего содержания интегрированных уроков классифицируются структура обучения и интегрированная технология данного типа урок-проекта. Ключевые Слова интегративный, компетентность, классификация, характеристика, технократический, нетрадиционный, выставочный, фактор. Abstract This article emphasizes the importance of organizing elementary classes in an integrated way, identifies some requirements and conditions, and describes in detail the general features of integrated classes. Also, based on the general content of integrated lessons, the structure of training and integrated technology of this type of lesson project are classified. Keywords


This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Grant Agreement No 101000794. Newsletter Magazine 4th Issue May 2023 In this Issue 1. SECRETed at a glance 2. Achievements 3. Get connected 4. Dissemination activities To gain access to our forthcoming Newsletters subscribe through our website. Check the previous issues of Newsletter HERE COPYRIGHT©


A Pilot Characterization Study Assessing Health Equity in Mental Healthcare Delivery within the State of Georgia Jacob Zelko, Malina Hy, Varshini Chinta, Emily Liau, Morgan Knowlton Background Mental health research is of particular to many in different communities across the globe. In the US specifically, the recent unprecedented spike in mental health disorders and surge in adverse outcomes stemming from mental illness (1) underscore the need for better understanding of mental illness. Based on literature about the social determinants of health and health disparities (2), it is known that the health landscape in the US is not equitable; mental healthcare is no exception to that. For this pilot investigation into mental healthcare delivery, we created a characterization study that characterized patients having conditions of bipolar disorder, depression, and suicidality in the state of Georgia using claims data. We investigated these three conditions because they are some of the more relatively understudied conditions in mental health research (3–5), are costly for both patients (6) and providers, and have high morbidity rates associated with them (1,7). The Georgia patient populations were characterized to determine baseline crude prevalence rates and initial work was done to investigate patients' loss to follow up of care after condition diagnosis. Methods For this pilot investigation, CMS claims data from 1999 - 2014 were utilized and went through the OMOP CDM ETL process to create a database adhering to OMOP CDM version 5.4. This database consisted of only patient information from the state of Georgia and totaled to approximately 2.2 million patients. Filtering algorithms were developed in this study's network package to stratify patient populations and subpopulations by strata such as condition, race, sex assigned at birth, and age groups. Crude prevalence rates of these subpopulations were calculated and used to characterize a baseline of these patients and to characterize early investigative questions around patients' loss to follow-up of care. Results From this pilot study, three things were demonstrated: 1) There exist large disparities in prevalence rates for Georgia CMS populations that exist acutely within a given general population's subpopulation groups. 2) Characterizations conducted at this fine level of control is not only feasible but flexible enough to motivate further in-depth strata-based analyses of depression, bipolar disorder, and suicidality. 3) Currently existing data collection practices by CMS are insufficient to properly represent the complexity of US minority population groups and future study will need complementary data sources to address this gap (8).


UM ESTUDO SOBRE AVALIAÇÃO DE APRENDIZAGEM EM TEMPO COVIDE19: SENTIDOS PRODUZIDOS PELAS DOCENTES DO ENSINO FUNDAMENTAL II Resumo Este trabalho surgiu a partir da pesquisa de mestrado, em desenvolvimento, com o objetivo de compreender os sentidos produzidos pelas docentes, a partir de um ateliê virtual com narrativas escritas e/ou orais, as práticas avaliativas realizadas frente ao tempo de pandemia Covid 19. Trata-se de um estudo de abordagem qualitativa, pesquisa e formação de perspectiva fenomenológica, realizada com seis professoras de uma determinada escola da rede pública do município de Cordeiros /BA. Nas conclusões iniciais deste estudo defende-se que é importante viabilizar uma formação pedagógica ao docente para que se possa refletir acerca de um elenco de alternativas que possibilitem uma avaliação mais prazerosa para ambos (docente e discente) com resultados mais efetivos. Palavras-chave: Avaliação da aprendizagem. Ateliê formativo; Aprendizagens narrativas. Introdução A pandemia causada pelo novo coronavírus (Sars-CoV-2), também chamado Covid 19, no início de 2020, atingiu a população em escala mundial. No Brasil, com a entrada do vírus em 11 de março 2020, foram tomadas as medidas da suspensão de atividades educacionais em território nacional, e o ensino remoto passou ser regulamentado como continuidade da implementação do calendário escolar de 2020-2021, conforme a Portaria nº 343/2020 do Ministério da Educação (MEC). Já se passou um ano e a crise do Covid 19 não passou, e a cada novo dia a situação vai ficando mais complexa. Pois, além dos desafios da luta pela vida, por causa da falta de vacina e devido ao negacionismos do atual governo, escolas e famílias que não raro ainda resistiam às tecnologias, tiveram que se adaptarem rapidamente às plataformas e conteúdos digitais para professores e estudantes, da educação básica ao ensino superior. Lembramos que o ensino remoto são “práticas pedagógicas mediadas por plataformas digitais, como aplicativos com os conteúdos, tarefas, notificações e/ou plataformas síncronas e assíncronas como o Teams (Microsoft), Google Classroom, Google Meet, Zoom [...]” (ALVES, 2020, p. 352). Nossa compreensão para educação remota é que a forma de ensinar precisa ser adequada às singularidades de cada contexto educacional, bem como, os procedimentos avaliativos, precisam estar voltados à compreensão dos processos de apropriação e construção de saberes. Como será que os professores da educação básicas estão utilizando as interfaces que estão disponíveis nas diversas plataformas, para planejar suas atividades avaliativas? Além da questão da pandemia, a problemática da avaliação já apontava que precisamos rever nossas concepções práticas de avaliação, pois muitas práticas estão voltadas apenas para seguir currículos, que não é uma “prática viável apenas transpor conteúdo dos documentos curriculares, prescindindo dos pilares do que constitui o fazer docente: o planejamento, a seleção de conceitos e objetos de conhecimento, a reflexão acerca do que, a quem e para que queremos ensinar” (VIEIRA E RICCI, 2020, P.2). São essas demandas pelas quais a educação vem passando ao longo do tempo, e que nos permite discutir e rever e pensar em ideias sobre a avaliação da aprendizagem. As novas discussões teóricas o papel desempenhado pelo professor e pelo aluno, redefine a escola com uma função social e nos 1/3


Water Governance: An Effective Model for Sub-Saharan Africa. Rafael Quijada Landaverde; Dr. Mary T. Rodriguez; Dr. Amanda Robinson; Rebecca Giannotti, Ph.D. Department of Agricultural Communication, Education, and Leadership Research Purpose This study aimed to examine the body of scholarly knowledge, research, and practice related to water governance systems. The objective was to identify the components of an adequate water governance system for the Sub-Saharan Africa region. Methodology For this theoretical study, researchers conducted a desktop review using multiple primary and secondary data sources, including international cooperation organization documents, journal articles, government reports, and websites. This research study is part of the Water for Governance Research project (GROWS) funded by USAID. The goal of GROWS is to identify and disseminate learnings around innovative governance models and tools that will help improve rural water service delivery in sub-Saharan Africa. Implications and Recommendations • Central and local governments should guarantee safe drinking water to all its inhabitants. However, it is most often the communities themselves that organize and ensure the distribution of water in sub-Saharan African countries. • The inadequate supply of water by government entities and the increasing demand for water resources has forced new policies to encourage private sector water supply (Foster, 2010). We recommend that future studies examine more closely the relationship between each of the governance elements identified; and use this model to evaluate governance in other water supply systems. • The implementation of water governance models capable of achieving transparency, accountability, equity, and trust could significantly reduce the private sector’s hesitance in investing in community water distribution systems. A water governance model only makes sense when it incorporates all actors in the system, including users, service providers, and government (Gianotti et al., 2018). • It is recommended to include and disseminate this model of water governance in those initiatives that seek to improve the conditions of water resources in Sub-Saharan Africa. Results Trust Accountability Transparency Equity The OECD explains that “trust is important for the success of a wide range of public policies that depend on behavioral responses from the public. Trust is necessary to increase the confidence of investors and consumers. Trust is essential for key economic activities, most notably finance. Trust in institutions is important for the success of many government policies, programs, and regulations that depend on cooperation and compliance of citizens” (OECD 2018). In a water system’s operations, trust is built in a bi-directional relationship between the service provider entity and the users. Those in charge of supplying water must ensure the quality and quantity of the service while respecting the operating conditions that govern the system. Users must adopt responsible consumption patterns and comply with the water system's obligations of payment and care (Gianotti et al., 2018) In a water system’s governance, the benefit must be equal and equitable among the users. This includes access and availability of water to all marginalized groups within a community. Finally, decision-making must be brokered between stakeholders or through an organizational structure that ensures the same opportunity for participation, especially for women and young people, in water governance. The USAID defines accountability as “the systems, procedures, and mechanisms that ensure that public officials and institutions perform their stated duties and uphold their responsibilities to the public while imposing restraints on their power and authority and providing for redress or sanction when these duties and responsibilities are not met” (USAID, 2013). In water governance, both the scheme and the users must be hold accountable for the


Voice Control in a Real Flight Deck Environment Michal Trzos1, Martin Dostal1, Petra Machackova1, and Jana Eitlerova1 1 Honeywell International, Aerospace Advanced Technology Europe, Turanka 1387/100, Brno, Czech Republic {michal.trzos,martin.dostal2,petra.machackova2,jana.eitlerova} @honeywell.com Abstract. In this paper, we present a methodology on how to implement multi- modal voice controlled systems by means of automatic speech recognition. The real flight deck environment brings many challenges such as high accuracy requirements, high noise conditions, non-native English-speaking users or limited hardware and software resources. We present the design of an automatic speech recognition system based on a freely available AMI Meeting Corpus and a proprietary corpus provided by Airbus. Then we describe how we trained and evaluated the speech recognition models in a simulated environment using the anechoic chamber laboratory. The tuned speech recognition models were tested in real flight environment on two Honeywell experimental airplanes: Dassault Falcon 900 and Boeing 757. Keywords: automatic speech recognition, multi-modal interaction, navigation display. 1 Introduction The modern flight decks in business and air transport aircraft are equipped with digi- tal flight instrument displays rather than analog dials and gauges. Such flight decks are termed as glass cockpits. Glass cockpits typically have a Primary Flight Display (PFD), shown on Fig. 1, providing flight information and Navigation Display (ND) (or multi-function display) providing the pilots with navigation route, moving map, flight planning or weather radar to name a few navigation display functions. Naviga- tion displays interaction is based on the graphical user interfaces and point-and-click paradigm. A keyboard and a cursor control devices (CCD) are used as primary inter- action means. The current interaction means brings couple of limitations; navigation displays are equipped with a huge number of functionalities, which together with graphical user interfaces and cursor control devices impacts efficiency. Many func- tions are accessible through time consuming visual navigation and pointing using cursor control device, which are kind of accurate but slow input devices. All the pointing on a graphical user interface requires pilot gaze on the display (head-down interaction) instead of providing the pilot the maximum time to look out the windows (head-up) which is important for the pilot, especially during taxi, take-off, approach and landing phase of flight. Acknowledgement This project has received funding from the Clean Sky 2 Joint Undertaking (JU) under grant agreement No 807097. The JU receives support from the European Union’s Horizon 2020 research and innovation programme and the Clean Sky 2 JU members other than the Union. Disclaimer The results, opinions, conclusions, etc. presented in this work are those of the author(s) only and do not necessarily represent the position of the JU; the JU is not responsible for any use made of the information contained herein.


Colección de ESMOS 1 ¿Sabías esto sobre la renina? María Esther Hernández-Huerta* iD Licenciatura en Biotecnología, Facultad de Ciencias Biológicas, Benemérita Universidad Autónoma de Puebla, Puebla, México. *Email: maria.hernandezhuer@alumno.buap.mx 08 de Noviembre de 2022 DOI: http://doi.org/10.5281/zenodo.7302634 URI: Editado por: Jesús Muñoz-Rojas (Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla). Revisado por: Lilia Isela López-Lara (Miembro de la Asociación Poblana de Ciencias Microbiológicas). Colección de ESMOS Resumen El trabajo de científicos como Richard Bright, Starling, y Claude Bernard, demostraron que en el hígado existe una secreción interna desconocida a parte de la externa, lo que resultaría en el descubrimiento de la renina en 1898 por Tigerstedt; este último la descubrió gracias a experimentos realizados en animales, donde comprobó que al inyectarla causaba hipertensión. La renina se trata de una enzima que es una glucoproteína de cadena simple, carboxipeptidasa de la familia de las proteinasas aspárticas que se activa a pH neutro [1].


2nd International Conference on Advanced Production and Processing 20th-22nd October 2022 Novi Sad, Serbia BOOK of ABSTRACTS


W W W . C E D A . A C . U K The Big 5 Live car free Fly less Switching to public transport, walking, cycling where possible. Consider switching to a more fuel-efficien t vehicle (i.e. electric or hydrid) Consider using trains/coaches to travel around Europe, or choose a holiday destination within the UK! Buy green energy Choose green energy suppliers or even better install your own solar panels Eat more plants Switching to a more plant-based diet is better for you and will cut down your green house gas emissions. Try t o challenge yourself and go meatless once or twice a week. Divest from fossil fuels Choose ethical banks that do not invest in fossil fuels. Here are some of the highest impact lifestyle changes we can make to cut down our green house gas emissions. CLIMATE PLEDGES CLIMATE PLEDGES


Exact Confidence Interval of Observed Proportion with Weighted Stratification factors and its Applications Ruji Yao, Amarjot Kaur, Qing Li Merck & Co., Inc., Rahway, NJ, USA It is common in clinical trials to construct exact confidence interval (CI) for observed proportions, which can be done without normality assumption for a wide range of proportions. A stratified randomization is often used to control for treatment confounding. We have proposed a method to define a distribution on an observed proportion with formula of Exact (Clopper-Pearson) Confidence Limits. In this presentation, we further extend the idea to define the distribution on an observed proportion with stratified factors, using independence among strata. We will show how to get the exact CI for an observed proportion with strata and the difference of such two proportions by these distributions. In general, we can expect a relatively narrower width of confidence intervals with strata information. 1. Define distribution on observed proportion by formula of Exact (Clopper- Pearson) Confidence Limits For binary data with probability of success 𝑝𝑝, let us consider using the observed proportion 𝑝𝑝̂ to get an estimated distribution of 𝑝𝑝. With distributions from both active 𝑝𝑝𝑎𝑎 and placebo 𝑝𝑝𝑝𝑝 group, we can obtain the estimated distribution of differences (𝑝𝑝𝑎𝑎− 𝑝𝑝𝑎𝑎) of two proportions and construct a confidence interval without making a normality assumption. The proposed method allows to get a distribution without having to select a prior parameters (α,β) for the Beta prior, which is typically used in the Bayesian method to derive a posterior distribution on an observe proportion 𝑝𝑝̂ = 𝑛𝑛1/𝑛𝑛. We propose using the method of exact Clopper-Pearson confidence limits to define a distribution directly on the observed proportion 𝑝𝑝̂ . As a background, the method attributed to Clopper and Pearson (1934) to get exact confidence confident limits is explained as follows: Exact (Clopper-Pearson) Confidence Limits for the binomial proportion are constructed by inverting the equal-tailed test based on the binomial distribution. The exact confidence limits pL and pU satisfy the following equations, for 𝑚𝑚= 1, 2, … 𝑛𝑛−1: ෍𝐵𝐵𝐵𝐵𝐵𝐵(𝑥𝑥, 𝑛𝑛 𝑥𝑥=𝑚𝑚 𝑝𝑝𝑝𝑝, 𝑛𝑛) = 𝛼𝛼/2 ෍𝐵𝐵𝐵𝐵𝐵𝐵(𝑥𝑥, 𝑚𝑚 𝑥𝑥=0 𝑝𝑝𝑝𝑝, 𝑛𝑛) = 𝛼𝛼/2 where 𝑝𝑝𝑝𝑝= (1 + 𝑛𝑛−𝑚𝑚+ 1 𝑚𝑚 𝐹𝐹(𝛼𝛼/2, 2(𝑚𝑚1 + 1),2(𝑛𝑛−𝑚𝑚+ 1))−1


LA-UR-23-20340 Approved for public release; distribution is unlimited. Title: Neutron Interferometry and Entanglement Author(s): Wang, Zhehui Intended for: The 53rd Winter Colloquium on the Physics of Quantum Electronics (PQE'23), 2023-01-09 (Snowbird, Utah, United States) Web Issued: 2023-01-13 (Draft)


Broth media cultivation of xylem microbiome from cultivated olive trees Anguita-Maeso, M1; Olivares-García, C1; Rivas, JC1; Navas-Cortés, JA1; Landa, BB1 1Institute for Sustainable Agriculture (IAS), Spanish National Research Council (CSIC), Córdoba, Spain.


Antagonism capacity of endophytes isolated from olive cvs in Apulia region Arafat Hanani1,2*, Franco Valentini1, Anna Maria D'Onghia1, Salvatore Walter Davino2 1 CIHEAM - Mediterranean Agronomic Institute of Bari, Via Ceglie, 9, I-70010, Valenzano (BA), Italy 2 Department of Agricultural, Food and Forest Science, University of Palermo, Palermo, Italy. *Corresponding Author: PhD. Arafat Hanani [Arafat.Hanani@unipa.it]


Students’ International Network for Astronomy SINA *Mahdi Rokni Manager of SINA *Akihiko Tomita, *Saba Izadi, Melika Gonbadi *Commission C1 WG Astronomy Education Research & Methods members


1 | P a g e T I T A N I C I N V E S T I G A T I O N What is the session about? Research questions This session aims to support children and teachers in using the scientific language of ‘observe’ and ‘observations’ to help children to work scientifically. Compare science with history to appreciate that science is only one way to answer questions. • I have learnt that science and history are disciplines • Some questions can be answered by science and history together • I can explain how science and history are similar and how they are different National curriculum content Science: Forces – water resistance History: A study of an aspect in British history that extends pupils’ chronological knowledge beyond 1066 Support & Free Materials 2 Investigation cards, experiment materials, Teacher notes, Student worksheets plus CPD webinars


ABSTRACT 49th ESCP virtual symposium on clinical pharmacy 19.10.2021–21.10.2021 Clinical pharmacy, working collaboratively in mental health care Published online: 29 November 2021  Springer Nature Switzerland AG 2021 Oral communications and Posters ORAL COMMUNICATION I OR01.1 Developing and validating a prediction model for in-hospital mortality associated with anticholinergic drug burden among older hospitalised patients with dementia Angela E. Lisibach1, 2, 3, 4, Nora Haltinner* 4, 5, Patrick E. Beeler6, Andrea Burden5, Chantal Csajka1, 2, 3, Monika Lutters4, 5 1Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, University of Lausanne, 2School of Pharmaceutical Sciences, University of Geneva, Geneva, 3Center for Research and Innovation in Clinical Pharmaceutical Sciences, University Hospital and University of Lausanne, Lausanne, 4Departement of Medical Services, Clinical Pharmacy, Cantonal Hospital of Baden, Baden, 5Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, 6Division of Occupational and Environmental Medicine, Epidemiology, Biostatistics and Prevention Institute, University of Zurich and University Hospital Zurich, Zu¨rich, Switzerland Background and Objective: After cardiovascular diseases and can- cer, dementia is the third most frequent cause of death in Switzerland among patients aged 65 years and older. A recent cohort study con- ducted in a regional hospital in Switzerland showed that a high anticholinergic drug burden in older patients is signiﬁcantly associ- ated with increased in-hospital mortality. We aimed to develop and validate a risk prediction model for in-hospital mortality in older patients with dementia and consider their exposure to anticholinergic drugs as a predeﬁned predictor. Design: Electronic health record data within the ﬁrst 24h of admis- sion was collected from 2015-2018. Included were inpatients C65 years old, hospitalised C48h, diagnosed with dementia according to ICD-10 codes. Outpatients and patients with stays [24h in the intensive care unit were excluded. The outcome was in-hospital mortality. The developed model was based on Naı¨ve Bayes using data from 2015–2016 as training set, the years 2017–2018 served as val- idation set. The candidate variables were obtained with the Minimum Redundancy Maximum Relevance (MRMR) variable selection algo- rithm and backward selection. Synthetic Minority Oversampling Technique (SMOTE) was applied within the training-set. Perfor- mance measures of interest were AUC, sensitivity and speciﬁcity. Results: In total, 2,595 patients were included. The training set contained 1266 patients (mean age 83.2±6.54 years, 60% female) of which 63 (5.0%) died during hospitalisation. Variables selected for prediction were: self-care index, delirium observation screening score, sodium, CRP, creatinine, GFR, chronic heart failure, hemi-/paraplegia, COPD, cancer, diabetes and the anticholinergic burden scales Cancelli, ACL, ADS and SCDL. Further, blood pres- sure, polypharmacy, age, BMI, and temperature were included. A ﬁrst validation for the ﬁnal model using the training set showed an AUC of 0.872, a sensitivity of 90.44% and a speciﬁcity of 68.50%. Using the validation set, we obtained an AUC of 0.771, a sensitivity of 63.01% and a speciﬁcity of 73.65%. Conclusion: The developed prediction model for in-hospital mor- tality showed an acceptable performance. It might be a useful tool to identify patients with dementia with a high risk for in-hospital mor- tality in order to implement interventions and management strategies during hospitalisation to improve patient outcome, however, further validation is required. OR01.2 Undergraduate students and educators’ views on interprofessional behaviour change support education in chronic disease Isa B. Fe´lix1, Carla Nascimento1, Patrı´cia Pereira1, Katja Braam2, Cathal Cadogan3, Judith Strawbridge4, Leona Cilar5, Lucija Gosak5, Nuno Pime


A New Introductory Book on Stellar Magnetic Activity Gibor Basri, UC Berkeley (basri@berkeley.edu) ★Comprehensive and Introductory ★ Concise summary of current knowledge ★ Written for advanced undergrad or above ★ Physics, observations, and history ★ Pointers to other reviews and details ★ 77 illustrative figures from papers (170 pages) ★ Atmospheric/active structures on stars ★ Variability, flares, and stellar outflows ★ Multi-wavelength spectral diagnostics ★ Multi-wavelength photometric diagnostics ★ Rotation-activity-age-mass relations ★ Direct detection of magnetic fields ★ Dynamo theory and magnetic cycles ★ Stars of all masses and ages ★ Pre- and post-main sequence stars ★ Appendix on LTE/NLTE radiative transfer


Poster STI 2022 Conference Proceedings Proceedings of the 26th International Conference on Science and Technology Indicators All papers published in this conference proceedings have been peer reviewed through a peer review process administered by the proceedings Editors. Reviews were conducted by expert referees to the professional and scientific standards expected of a conference proceedings. Proceeding Editors Nicolas Robinson-Garcia Daniel Torres-Salinas Wenceslao Arroyo-Machado Citation: Confraria, H., & Pereira, T. S. (2022). Research funding in Portuguese-speaking African countries: Patterns and alignment with health needs. In N. Robinson-Garcia, D. Torres-Salinas, & W. Arroyo-Machado (Eds.), 26th International Conference on Science and Technology Indicators, STI 2022 (sti22133). https://doi.org/10.5281/zenodo.6975512 Copyright: © 2022 the authors, © 2022 Faculty of Communication and Documentation, University of Granada, Spain. This is an open access article distributed under the terms of the Creative Commons Attribution License. Collection: https://zenodo.org/communities/sti2022grx/


Multi-purpose neutrino detector 2 km underground at SNOLAB o Extensive physics programme in all phases o Main goal: search for 0νββ of 130Te! The SNO+ Journey to 0𝝼ββ Ana Sofia Inácio, William Parker, Benjamin Tam on behalf of the SNO+ Collaboration; NuPhys2023: Prospects in Neutrino Physics, London, Dec 18-20, 2023 The SNO+ Experiment Acrylic vessel 9362 PMTs 6 m


Target Identification Identifying potential and druggable targets for developing new drugs is the first major step for curing a disease, which includes the understanding of the cellular, molecular, biochemical complexities associated with a specific disease. The classical hypothesis of ‘one gene, one drug, one disease’ in the drug discovery paradigm may have contributed to the low success rate in drug development. Using AI and related technologies in the target identification process allows scientists and pharmaceutical companies to really explore all the available evidence to better understand a disease and its underlying biology. Our team has focused on target identification, with growing amounts of data supporting early decision making. Regular methods are based on high throughput omics-datasets, such as genome- wide association scans, gene expression analysis from tissue to a single cell, miRNA analysis, proteomics, metabolomics, post-translational modifications, cellular imaging, etc. Target-based and phenotypic screening are most commonly used approaches for finding and validating drug targets. Computational approaches offer novel testable hypotheses for systematic, unbiased identification of molecular targets of known drugs. With the rapid development of AI and machine learning technologies, unstructured information from omics, text and image analytics, public databases, systems biology can be integrated. Our expert team can help clients extracting knowledge from a multitude of resources and thus enabling science-based decisions. Network-based methodologies for drug–target interactions (DTI) predictionin silico:


SÉMINAIRES PUPPETPLAYS [Online] 1 | 2020 Qu’est-ce qu’un répertoire pour marionnettes ? What is a repertoire for puppets? PUPPETPLAYS-Reappraising Western European Prof. Dr. Didier Plassard European Research Council (GA 835193) Université Paul-Valéry Montpellier 3 (France) __________________________________________________________ Pulcinella, Punch, Polichinelle… Continuités et discontinuités dans le répertoire des marionnettes à gaine (17e-19e siècles) Didier Plassard (Université Paul-Valéry Montpellier 3) __________________________________________________________ Electronic version Publisher: PuppetPlays Electronic reference Didier Plassard, Pulcinella, Punch, Polichinelle… Continuités et discontinuités dans le répertoire des ã PuppetPlays huma-num.fr Huma-Num la TGIR des humanités numériques Pulcinella, Punch, Polichinelle… Séminaires PuppetPlays [On line] 1 I 2020 1 URL: https://nakala.fr/10.34847/nkl.c661590g DOI: 10.34847/nkl.c661590g marionnettes à gaine (17e-19e siècles), Séminaires PuppetPlays [Online] 1 2020, Online since 14/01/2021 December, connection on ...................... URL : https://nakala.fr/collection/10.34847/nkl.b64d9he8 DOI : 10.34847/nkl.b64d9he8 Repertoires for Puppet and Marionette Theatres


PC-SAFT parametrization of pharmaceuticals based on more than experimental solubility data Martin Klajmon Computational Thermodynamics Research Group, UCT Prague #105 martin.klajmon@vscht.cz @CervinkaGroup sites.google.com/view/cervinkagroup


A semi-empirical model for the structure of massive galaxies: size evolution, progenitor bias and the galaxy-halo connection Lorenzo Zanisi, Francesco Shankar & A Rodriguez-Puebla, V. Avila-Reese, H. Fu, A. Lapi, P. Saracco, M. Giavalisco, E. Daddi, A. Dekel, A. Faisst, F. Buitrago, M. Huertas-Company


Antecedentes Internacionales 3 . 3 . 4 . 4 . Objetivo: Describir la prevalencia de Trastorno por Estrés Postraumático (TEPT) en militares de una institución del Ejército del Perú (Ccosi, 2019). Este estudio tiene un enfoque cuantitativo, con un diseño no experimental, de corte transversal y de tipo descriptivo. Se aplicó 1 instrumento. Los resultados muestran que existe en general un 22% que presenta sintomatología de estrés postraumático. Referencias Síntomas del Trastorno por Estrés Postraumático en soldados profesionales del Batallón de Infantería N° 7 General José Hilario López a partir de su experiencia en combates terrestres. Los resultados muestran que los voluntarios tienen una prevalencia del 2,8 al 7,8% de TEPT, a diferencia de los soldados de Naciones Unidas, la prevalencia es de 5,6% al 20,8% (mayor). Ccosi, A. (2019). Trastorno por estrés postraumático en militares de una institución del Ejército del Perú (Tesis de pregrado). Universidad Peruana Unión, Lima. Dolores, B., Vesna, A., Kaliterna, M., Lisec, L., Beg, A., Igna, B., Kudric, M., Zeljana, S., Vikica, K y Nela, P. (2014). Comorbilidades con el trastorno de estrés postraumático (TEPT) entre los veteranos de combate: 15 años después del análisis. International Journal of Clinical and Health Psychology, vol. 15, p. 81-92. Kaspersen. M. y Stig, M. (2003). Síntomas de Estrés Postraumático entre los soldados de Naciones Unidas y el personal perteneciente al voluntariado. Eur. J. Psychiat, vol. 17(2), p. 69-77. Rodríguez, F. (2018). Percepción del Estrés, afrontamiento y ajuste psicológico en despliegues militares (Tesis de doctorado). Universidad de Santiago de Compostela, Madrid. 1 .1 . Síntomas de Estrés Postraumático entre los soldados de Naciones Unidas y el personal perteneciente al voluntariado Objetivo: Describir las reacciones postraumáticas entre dos grupos de personas expuestas a la guerra (Kaspersen & Berge, 2003). Este estudio tiene un enfoque mixto, de tipo comparativo. Se aplicaron 4 instrumentos. Comorbilidades con el trastorno de estrés postraumático (TEPT) entre los veteranos de combate: 15 años después del análisis 2 . 2 . Objetivos: Comparar la frecuencia de trastornos somáticos en un grupo de militares víctimas de guerra y un grupo no víctima. Determinar la influencia de los factores sociodemográficos en trastornos somáticos en momentos de guerra (Dolores et al., 2014). Este estudio tiene un enfoque cuantitativo, de tipo descriptivo. Los resultados muestran que el 62% de los sujetos presentaron TEPT, en más de la mitad de los sujetos se presentan cambios de personalidad después del evento traumático, y el 38% presentó el trastorno depresivo. Percepción del estrés, afrontamiento y ajuste psicológico en despliegues militares Objetivo: Analizar el desarrollo del estrés percibido y la sintomatología asociada a la salud mental (Rodríguez, 2018). Este estudio tiene un enfoque mixto, con un diseño prospectivo. Se aplicaron 2 instrumentos Los resultados muestran un incremento de estrés percibido, cuando los militares se encuentran en un despliegue militar, porque son experiencias exigentes que inciden entre un 25 y 30 % en el surgimiento del TEPT. Trastorno por estrés postraumático en militares de una institución del Ejército del Perú Presentado por: Angie Daniela Toro Lopez Anghie Xilena Muñoz Burbano


La Matrice de Pi est un outil génératif utilisé en idéation, techniques de créativité et accomplissement de projet. Il a été conçu par Thomas Pieds en 2017, et abouti dans sa forme définitive en 2019. Le mot « Pi » est sans rapport avec le chiffre grec (π), il est tiré des premières lettres du nom de son inventeur. La Matrice de Pi se présente comme un algorigramme à plusieurs entrées (4, 8, et 16), impliquant une exécution algorithmique en trois étapes séquentielles. Elle permet de générer une solution créative en fonction d’un contexte multi-tendanciel délibérément hétérogène et contradictoire. Son optimisation est liée à la pertinence attributionnelle des pôles tendanciels au départ, puis à leur logique à converger de manière réflexive et connexe vers un noyau central tout au long de sa résolution. C’est par influence mutuelle des agrégats multi-tendanciels et implication combinatoire des processus transversaux, que la solution créative en cours de potentialisation tend vers une validité fonctionnelle et un résultat unifié. Lorsque chacune des variables se trouve en interdépendance et réciprocité au sein de l’algorigramme, on considère que le produit idéel et son écosystème sont harmonisés en cohérence. On parle alors de schéma d’attribution de valeurs fini et de positionnement sémantique viable. S’inscrivant dans un procédé heuristique ou itératif, les mécanismes d’émergence de la Matrice de Pi sont favorisés par le caractère dynamique et rétroactif de son modèle organisationnel. Une large place est laissée à l’erreur et à l’ajustement créateur tant l’élaboration cognitive, la flexibilité psychologique d’apprentissage et la transformation des connaissances sont au cœur de son approche. Investigations empirico et hypothético-déductives, circularité exploratoire et stimulations pseudo- aléatoires, y sont donc conviées jusqu’à l’obtention d’un résultat significatif. Malgré ses propriétés objectivantes, le résultat vaut pour une situation donnée dans un cadre expérienciel fini, sans exonération d’être réévalué ultérieurement, en cas de mutation sémantique de l’une de ses variables par exemple, ou réajustement attributionnel de l’un de ses pôles, consécutivement à un nouveau balisage contextuel. Étant précisé que, de par sa nature autopoïétique, l’actualisation d’une repolarisation partielle n’engage pas forcément le résultat final ni l’équilibre structurel de l’organisation matricielle. L’utilisation de la Matrice de Pi en milieux éducatifs, professionnels ou de formation, se révèle être un accélérateur de créativité, aussi bien qu’un instrument d’orientation et repère structurel à des fins opérationnelles et stratégiques. Elle fait partie des « aides à la décision » dans sa façon de visualiser un contexte, synthétiser, classifier et réidentifier des problématiques, évaluer les enjeux et rationnaliser les marges d’actions avant d’établir un objectif, obtenir des solutions originales en lien avec les réalités socio-économiques et macro-environnementales d’une situation.


World Awareness for Children in Trauma programme (WACIT: www.wacit.org): The Story so far The WACIT programme was designed to address the UN’s Sustainable Development Goals for Poverty, promoting health and wellbeing, and reducing inequalities, in addition to the overarching commitment to ‘leave no-one behind’. WACIT contributes to organisational capacity-building, supporting in-country community partners to develop culturally appropriate, research-informed frameworks for service delivery that ensures traumatised children continue to benefit longer term. The programme has the dual objective of enhancing practice, by integrating psychosocial skills in relation to professionals, community volunteers and agency roles; and to improve service delivery by re-focusing provision, and connecting agencies and communities to maximize their strengths and resources. These components were chosen to reflect international policy and direction, and following consultation with local stakeholders (see evidence below). Local co-production was ensured throughout the programme by a lead local agency engaging services, community and religious groups. Since 2015, the programme has potentially benefitted over 44,000 children and young people in 14 countries who have experienced trauma—in refugee camps; care facilities; settlements; or through homelessness - by training approximately 1,200 professionals (from health, social care, education and non-statutory agencies) and community volunteers (paraprofessionals) with the skills to identify trauma and support them. To date, we have completed the following sequential phases: Phase 1 Established readiness and barriers of child and adolescent mental health service provision among drivers in LMIC disadvantaged communities (Getanda et al., 2017; Tamburrino et al., 2018). Phase 2 Developed and implemented practice-focused capacity building. Stakeholders from six LMIC welcomed WACIT’s interdisciplinary and scaled approach (Vostanis et al., 2019b). Phase 3 Developed the WACIT service transformation framework, supporting training manual (Smit & Vostanis, 2018) and digital tools. This framework aims to improve services on six domains: safety, parent support, school and community, primary care, counselling, and mental health provision.


Open Schools Journal for Open Science Vol. 3, 2020 Nano-chip for cancer diagnostics Manaj L. BG Vocklabruck Manaj L. BRG Schloss Wagrain Joubert I.A. Dept. Biosciences, University of Salzburg Geppert M. Dept. Biosciences, University of Salzburg Himly M. Dept. Biosciences, University of Salzburg https://doi.org/10.12681/osj.22593 Copyright © 2020 L. Manaj, L. Manaj, I.A. Joubert, M. Geppert, M. Himly To cite this article: Manaj, L., Manaj, L., Joubert, I., Geppert, M., & Himly, M. (2020). Nano-chip for cancer diagnostics. Open Schools Journal for Open Science, 3(2). doi:https://doi.org/10.12681/osj.22593 http://epublishing.ekt.gr | e-Publisher: EKT | Downloaded at 02/03/2021 01:55:40 |


Laboratory of Plasma Physics, École Polytechnique/CNRS, Palaiseau, France Lina.hadid@lpp.polytechnique.fr 05/04/2021 Laboratoire de Physique des Plasmas Solar Orbiter’s first Venus flyby: observations from the Radio and Plasma Wave instrument L. Z. Hadid, N. J. T. Edberg, T. Chust, D. Píša, A. P. Dimmock, M. W. Morooka, M. Maksimovic, Yu. V. Khotyaintsev, J. Souček, M. Kretzschmar, A. Vecchio, O. Le Contel, A. Retino, R. C. Allen, M. Volwerk, C., M. Fowler, L. Sorriso-Valvo, T. Karlsson, O. Santolík, I. Kolmašová, F. Sahraoui, K. Stergiopoulou, X. Moussas, K. Issautier, R. M. Dewey, M. Klein Wolt, O. E. Malandraki, E. P. Kontar, G. G. Howes, S. D. Bale, T. S. Horbury, M. Martinović, A. Vaivads, V. Krasnoselskikh, E. Lorfèvre, D. Plettemeier, M. Steller, Š. Štverák, P. Trávníček , H. O’Brien, V. Evans, V. Angelini, M. C. Velli, and I. Zouganelis


Alpha spectrometry measurements for low-background experiments M. Czubak, G. Zuzel M. Smoluchowski Institute of Physics, Jagiellonian University in Cracow NuPhys2023: Prospects of Neutrino Physics 18th December 2023


The Nature of the Fornax 6 Globular Cluster with Magellan/M2FS Spectroscopy Fornax dSph is one of the brightest dSph satellite galaxies of the MW. It is one of the only dwarf galaxies to have globular clusters at its stellar mass (~5x10^ Msolar). Fornax has 6 globular clusters and the 6th has recently been rediscovered with DECam imaging (Wang et al. 2019). We obtained Magellan/M2FS spectroscopy of individual red-giant branch stars to conﬁrm the Fornax 6 cluster and to determine its properties. Cutout centered on the F6 cluster. From Wang et al 2019 Andrew Pace (Carnegie Mellon University) Rediscovery of Fornax 6 Globular Cluster From Wang et al 2019 Based on Pace et al 2021 (arXiv:2105.00064)


Importance and particularities of Astronomy Education: what the Research says 3rd Shaw-IAU Workshop on Astronomy for Education (2021) Astronomy Education Research 101 Rodolfo Langhi Professor at the Department of Physics and Graduate Program in Education for Science, coordinator of Astronomy Observatory, at the São Paulo State University, School of Sciences (Brazil)


09/2021 15 → 25 MIDA Networkwide Activity


Heterogeneous changes of soil microclimate in high mountains and glacier forelands S. Marta, A. Zimmer, M. Caccianiga, M. Gobbi, R. Ambrosini, R.S. Azzoni, F. Gili, F. Pittino, W. Thuiller, A. Provenzale & G.F. Ficetola


AN´ALISIS DE RIESGOS DE CIBERSEGURIDAD EN ARQUITECTURA DE VEHICULOS AUTOMATIZADOS 1,2Leonardo Gonz´alez, 2Myriam Vaca, 2Ray Lattarulo, 1Isidro Calvo, 2Joshue P´erez, 2Alejandra Ruiz {leonardo.gonzalez , myriam.vaca, ray.lattarulo, joshue.perez, alejandra.ruiz}@tecnalia.com, isidro.calvo@ehu.eus 1Universidad del Pa´ıs Vasco 2Tecnalia Research and Innovation Resumen Los veh´ıculos conectados y automatizados han sido recientemente concebidos como entes ci- berf´ısicos, estrechamente relacionados con la red del Internet de las cosas (IoT). Este hecho supone un incremento en la superﬁcie de ataque del veh´ıculo, que junto a la creciente tendencia hacia veh´ıculos automatizados, hacen que estos riesgos de ciberseguridad puedan tener conse- cuencias catastr´oﬁcas en seguridad vial. En el presente trabajo se expone un an´alisis de riesgos de ciberseguridad en el marco de una arquitectura de veh´ıculos automatizados. Este an´alisis previo se realiza en el contexto de dos escenarios de estudio en maniobras cooperativas. Inicialmente se presenta un estado del arte de la ciberseguridad en automoci´on, as´ı como tambi´en su repercusi´on en entornos automatizados, haciendo especial ´enfasis en las comunicaciones entre veh´ıculos y con infraestructura. Adem´as, se analizan dos maniobras cooperativas, y se ilustran una serie de posibles ataques en la plataforma. Palabras clave: ciberseguridad, veh´ıculos automatizados, seguridad, maniobras cooperati- vas. 1. Introducci´on Las tecnolog´ıas de informaci´on y comunicaci´on li- deran el avance en la era digital, as´ı mismo for- man parte importante del desarrollo de sistemas inteligentes de transporte (SIT). Los SIT ofrecen la oportunidad de mejorar la seguridad de trans- porte, reducir el impacto ambiental y favorecer la productividad y eﬁciencia a trav´es de la integra- ci´on de sistemas de comunicaci´on y percepci´on en veh´ıculos inteligentes. El desarrollo de sistemas de comunicaciones en veh´ıculos para la mejora de la eﬁciencia y la mo- dernizaci´on de la infraestructura de transporte ha sido un foco importante en el ´area automotriz. Sin embargo, recientemente con el auge del veh´ıculo automatizado, la comunicaci´on vehicular supone tambi´en un agregado de seguridad a estos siste- mas, previendo obst´aculos no visibles para un co- che, o previniendo de eventualidades en la v´ıa, invisibles al rango de visi´on de la sens´orica del veh´ıculo. En la actualidad la mayor´ıa de los fabricantes ya ofrecen alg´un nivel de automatizaci´on a trav´es de una serie de sistemas ADAS (Advanced Driver- assistance Systems). Estos disminuyen los riesgos en la v´ıa mediante la automatizaci´on de algunas tareas de conducci´on y prevenci´on de colisiones, y pueden ser considerados sistemas nivel 2, de acuer- do al est´andar SAE J3016. Los veh´ıculos conectados son un ente ciberf´ısico; una red de elementos interconectados, con m´ulti- ples unidades de control electr´onico (ECU) con co- municaci´on intra-vehicular, comunicaciones exter- nas con infraestructura inteligente, otros veh´ıculos e inclusive Internet. Esta expansi´on en las capa- cidades de comunicaci´on del veh´ıculo genera un incremento en la superﬁcie de ataque, en cuanto a riesgos de seguridad inform´atica se reﬁere. En este trabajo se presenta un estudio breve so- bre ciberseguridad en los veh´ıculos automatizados y conectados, y su repercusi´on en el riesgo vial. Adem´as, se realiza un an´alisis m´as detallado de estos riesgos sobre la arquitectura de veh´ıculos automatizados propuesta en [1]. Adicionalmente se proponen dos casos de estudio de maniobras cooperativas. El resto del art´ıculo esta distribuido de la siguien- te forma: en la secci´on 2 se realiza un resumen del estado del arte en la ciberseguridad y la rela- ci´on con riesgos en veh´ıculos automatizados. En la secci´on 3 se presenta la arquitectura mencionada antes junto a su respectivo an´alisis en el entorno de ciberseguridad y se describe la plataforma de pruebas. En la secci´on


PREVENTIVE CONSERVATION PROJECTS ON LAM MATERIALS PROJECTS ON LAM MATERIALSAT THE INAF AT THE INAF --ASTRONOMICAL ASTRONOMICALOBSERVATORY "G. S. VAIANA" OBSERVATORY "G. S. VAIANA" OFOFPALERMO PALERMOMaria Maria Rosalia Rosalia Carotenuto, Donatella Randazzo, Carotenuto, Donatella Randazzo, Ileana Ileana Chinnici Chinnici --INAF INAFGiada Giada GenuaGenua- -University Universityof Palermo of Palermo LISA IX: Multidimensional Astronomy Librarianship. From Open Science to the Preservation LISA IX: Multidimensional Astronomy Librarianship. From Open Science to the Preservation of Astronomical Heritage of Astronomical Heritage


“Sedimentology to face societal challenges on risk, resources and record of the past” Abstract Book ISBN 978-88-944576-2-9


The aim of the eMT cluster: The development of a unique ecosystem of technologies that will accelerate (fast digital o n boarding) and at the same time reduce the cost of adaptati on of business es of a ll siz es to Digi tal Transformation. The eMT Metaplatform technology module is a combination of technological applications aimed a t serving the needs of businesses from various sectors in the context of their digital transformation. Composing Industry4.0 in the eMT cluster, advanced IoT technologies, specialized sensors, data warehouses , Busines s Intelligence , forecastin g methods , Artifici al Intelligenc e, Machi ne Learni ng & De ep Learni ng, resou rce and mater ial managem ent syst ems ( ERP, MRP, PMS, et c.), sys tems for integra ting the ord ering pr ocess wit h its cos ting, mecha nism s fo r easy development of special-purpose websites and methods for easy cloud management are used. eMT MetaPlatform


La Red de Nodos de Igualdad de Género de la UCM es una red colaborativa de trabajo integrada por personas referentes en cada facultad para temas relacionados con la Igualdad de Género en la UCM. En funcionamiento desde 2018, integra a personas de todas las disciplinas y su objetivo principal es la realización de actividades de diagnóstico de género, de sensibilización y formación y de diseño participativo de medidas de igualdad, tanto para el Plan de Igualdad de la UCM como para implementarse a nivel de facultades y departamentos. Este material es el resultado de un trabajo de consulta de la red de Nodos sobre las prácticas y experiencias en la incorporación de la perspectiva de género en la docencia en la UCM. Se han identificado necesidades y elaborado recomendaciones muy prácticas que podemos incorporar en nuestro día a día. Si quieres saber más sobre la Red de Nodos puedes consultar www.ucm.es/supera/ Material realizado por la Red de Nodos de Igualdad de Género Constituida en el marco del proyecto SUPERA (Supporting the promotion of Equality in Research and Academia), financiado por el programa H2020 de la Unión Europea para apoyar el diseño y aprobación de Planes de Igualdad de Género. Textos: Paula de Dios Ruiz Lorena Pajares Sanchez Diseño: Irene Lizundia Benedicto


1 Pompeu Fabra University, Barcelona, January 25, 2018 This work is licensed under Creative Commons Attribution 4.0 International Lars Holm Nielsen CERN, IT Department


Legislative regulatory mechanisms for reducing the negative effects of pesticides on public health Gergana Nikolova1, Iliyan Kostov2, Stefan Baliev3 1 Faculty of Veterinary Medicine, Trakia University, Stara Zagora, e-mail: gnikolova.vet@gmail.com 2 Risk Assessment Centre, Sofia 3 Student, Faculty of Plant Protection and Agroecology, University of Agriculture, Plovdiv Abstract The wide use of pesticides to control pests on crops had driven the public attention in the recent years towards the potential risks, arising from their application. The various groups of plant protection products, depending on their main activity, have been constantly improved in order to ensure they are inexpensive, highly effective and with limited risk to the environment and public health. In Europe, like in the other countries worldwide (for example in North America) there have been implemented certain legislative basis and control measures for the purpose of regulation the use of pesticides and the hazards on humans and natural resources. With the present work we tried to analyze the existing legal framework in EU, concerning the evaluation, authorization, placing on the market and the communication on PPPs (Plant Protection Products). We also tried to point out the effects of implementation of the coordinated multi-national programme for control of pesticides. Key words: pesticides/plant protection products; EU legal framework; public health; risk; maximum residue levels. Законови регулаторни механизми за намаляване неблагоприятните ефекти от употребата на пестициди върху общественото здраве Гергана Николова1, Илиян Костов2, Стефан Балиев3 1 „Ветеринарно законодателство и мениджмънт”, Ветеринарномедицински факултет, Тракийски университет, Стара Загора; e-mail: gnikolova.vet@gmail.com 2 Дирекция „Оценка на риска”, Център за оценка на риска, София 3 Студент, Факултет „Растителна защита и агроекология”, Аграрен университет, Пловдив Резюме Широката употреба на пестициди за контрол на вредителите по земеделските култури насочи през последните години публичното внимание към потенциалните рискове от приложението им. Продуктите за растителна защита от различни групи, съобразно тяхната активност, са постоянно обект на усъвършенстване за постигане на гаранции за ниска себестойност, висока ефективност и намален риск за околната среда и общественото здраве. В Европа, подобно на други страни по света (напр. държавите от Северна Америка), са въведени конкретни законови разпоредби и контролни мерки за регулиране употребата на пестициди и рисковете за хората и природните ресурси, произтичащи от тях. С настоящата разработка направихме опит да анализираме съществуващата законова рамка на ЕС относно оценката, регистрацията, пускането на пазара и комуникацията на ПРЗ (продукти за растителна защита). Същевременно разгледахме и ефектите от приложението на координираната мултинационална програма за контрол на пестицидите. Ключови думи: пестициди/продукти за растителна защита; европейска законова рамка; обществено здраве; риск; максимално допустими граници на остатъчни вещества.


issn 1468-1331 volume 31 | supplement 1 June 2024


LOGO2ndAnnual Conference On Health And Food Science TechnologyPREPARATION AND EVALUATION OF PLANTEXTRACT MICROCAPSULES USING CHITOSAN Buanasari, Warlan Sugiyo, Heri R Nusaputera College of Pharmacy CHITOSAN EXTRACT


Poster STI 2022 Conference Proceedings Proceedings of the 26th International Conference on Science and Technology Indicators All papers published in this conference proceedings have been peer reviewed through a peer review process administered by the proceedings Editors. Reviews were conducted by expert referees to the professional and scientific standards expected of a conference proceedings. Proceeding Editors Nicolas Robinson-Garcia Daniel Torres-Salinas Wenceslao Arroyo-Machado Citation: Strotmann, A., & Zhao, D. (2022). Mapping controversial content on Wikipedia. In N. Robinson-Garcia, D. Torres-Salinas, & W. Arroyo- Machado (Eds.), 26th International Conference on Science and Technology Indicators, STI 2022 (sti2214). https://doi.org/10.5281/zenodo.6979667 Copyright: © 2022 the authors, © 2022 Faculty of Communication and Documentation, University of Granada, Spain. This is an open access article distributed under the terms of the Creative Commons Attribution License. Collection: https://zenodo.org/communities/sti2022grx/


Image-1 image1 Large scale view of Hubble Deep Field with some special picture of galaxies and supernova Somnath Chakraborty Khano High School(galsi, burpa burdwan, india) The Hubble Deep Field is an image of a small region on the north sky near to the ursa major star cluster. This H.D.F region is populated by galaxies, Black hole. This region is very important to study of early universe.


https://doi.org/10.53692/Anais2022COEMCO 1 Congresso Brasileiro de Educação Médica | 2020 | Virtual ANAIS DOS CONGRESSOS REGIONAIS DA ABEM 8° COEMCO “Tecnologia de Inovação no Ensino Médico em tempos atuais” Virtual, 08 de abril a 10 de abril de 2022


By Polytechnic University of Valencia (UPV) Methodology to estimate Decarbonisation potential RES4CITY CASE STUDY #3 at the neighborhood level


In silico and cheminformatics enrichment analysis to increase confidence in in vitro high-throughput screening (HTS) results: Application to Tox21 thyrotropin-releasing hormone receptor (TRHR) assay Mahmoud Shobair1*, Dan Chang1, Ryan Lougee3, Katie Paul Friedman1, Chris Grulke1, Jinghua Zhao3, Ruili Huang3, Menghang Xia3, Ann Richard1 1Ctr. for Comput. Toxicol. & Exposure, ORD, U.S. EPA; 2ORISE, Oak Ridge, TN, 3Nat. Ctr. Adv. Translational Sciences, NIH, Bethesda, MD, *Currently P&G, Cincinnati, OH Abstract #252 • Relating biochemical outputs to molecular initiating events (MIEs) and adverse outcome pathways (AOPs) is challenging, particularly when the relationship between the biochemical output and MIE is indirect, as is the case here • Tox21 thyrotropin-releasing hormone receptor (TRHR) is a potential target in the thyroid hormone AOP, but is lacking confirmatory or orthogonal assays (K. Paul Friedman, 2019) Objectives Develop and apply a structure-based data enrichment and knowledge contextualization workflow to identify likely TRHR false positives and discriminate true receptor binders identify structure-activity patterns using chemotype-enrichment analysis (Wang et al., 2019) filter noise from cytotoxicity or assay interference (Borrel et al., 2020) use 3D pharmacophore modeling to prioritize chemicals capable of binding to TRHR as well as modulators likely to interfere with binding (Kaur et al 2005) Background o TRHR is a GPCR (G protein- coupled receptor) with few known agonists or antagonists. o Assay measures agonism or antagonism for TRHR through the Gq-Ca2+ pathway. Challenge: prioritize Tox21_TRHR assay actives for hazard evaluation based on likelihood of binding to the receptor


1 Stephanie Brandt – Lecturer, MA Creative Practice for Narrative Environments, Central Saint Martins, College of Art and Design, University of the Arts, London, GB stephanie@spacepilots.net Conversation Pieces [Case Study B] Abstract The proposed project draws on habit, format, literature and space in order to construct an experimental representational system engaging with design and emotions. Photography and text are utilised to provide descriptive accounts of actions through space and time, exposing the tenuous boundaries between somebody’s life and the lived through environment. Devised through a series of dialogues the study explores the material and contextual structure of issues of habit and architecture. Trying to pervade and redefine each individual’s own daily routines and common perceptions the conversations are aiming towards both, an emotional and explanatory experience of our environment. How is space structured? By physical architectural elements such as walls or by words that describe the quality and matter of space? While both methods are understood as equally valid, this work chooses especially to explore how the re-contextualisation of words can lead to the development of new spatial qualities and emotional responses. How does this new identity make the design different from how it is historically conceived, traditionally understood and most important, conventionally used? - The aim is to structure a new imaginary scene, transforming an ordinary urban space into a sensory narrative environment, and as such conveying the [e]motions of the human subjects of the place.


Design and Integration of JUNO-OSIRIS Narongkiat Rodphai and Zhimin Wang on behalf of JUNO Collaboration Institute of High Energy Physics, Beijing, 100049, China University of Chinese Academy of Sciences, Beijing, 100049, China The Jiangmen Underground Neutrino Observatory (JUNO) is a neutrino detection experiment characterized by an acrylic sphere, measuring 35.4 me- ters in diameter, containing 20,000 tons of liquid scintillator. This sphere is encompassed by as many as 17,600 photomultiplier tubes (PMTs) with a 20- inch diameter, achieving an overall coverage of 77.9%. With these impressive capabilities, the JUNO experiment aims to achieve an exceptional effective energy resolution of 3% at 1 MeV. The Online Scintillator Internal Radioactivity Investigation System of JUNO (OSIRIS) serves as a precursor detector, around 100 meters aside in horizontal of the site of the JUNO detector underground, tasked with monitoring and examining the purity of the liquid scintillator prior to its transfer to the JUNO central detector. The OSIRIS, also as a pre-detector of JUNO, is constructed with a cylindrical acrylic vessel designed to hold 18 tons of liquid scintillator. It is situated within a 9-meter height cylindrical tank filled with 550 tons of pure water. This detector was specifically engineered to search for the fast coincidence decays of 214Bi -214Po and 212Bi -212Po in the decay chains of 238U and 232Th, respectively. OSIRIS has been designed to reach a sensitivity of 10−16 g/g for U/Th to test scintillator radiopurity to the level required for the detection of solar neutrinos. Additionally, 64 20-inch microchannel plate PMTs (MCP PMTs) were positioned around the liquid scintillator vessel to observe incoming interactions, along with an additional 12 20-inch MCP PMTs for the water Cherenkov muon veto system. The OSIRIS pre-detector has been fully constructed and integrated, pro- viding a plenty of preliminary results from the air runs. The next step in the process involves commencing the filling soon, aiming to involve an in-depth examination of the impurities within the liquid scintillator. PRESENTED AT NuPhys2023, Prospects in Neutrino Physics King’s College, London, UK, December 18–20, 2023


Super-resolution in astronomical images: enhancing object detection Irene Pintos Castro USC / CEFCA ipintoscastro@gmail.com Manuel Fern´andez Delgado USC (Supervisor) Andr´es del Pino CEFCA (Supervisor) Abstract—Using paired images of JAST/T80 Telescope in OAJ and of Hubble Space Telescope we aim at increasing the resolution of JAST/T80 images with the objective of enhancing object detection. Higher resolution versions of JAST/T80 images in crowded areas of the sky will significantly increase the number of stars and/or galaxies detected, enabling a better measurement of their photometry. We pre-processed both low-resolution and high-resolution images to build a dataset of paired crops, which is used to train the Real-ESRGAN neural network. We are able to get super-resolved images with a 4× scale and a FSIM=0.8903, showing an improvement in the source detection in crowded areas. However, visual inspection of bright stars and nearby galaxies reveals that there is room for learning a better model that can reproduce the PSF and the details of the extended objects. I. INTRODUCTION Telescopes are the instruments we use to observe our Universe. The cameras installed on them provide us with the data needed for its study: images and spectra. Astronomical observations from Earth are always limited by the presence of the atmosphere. While space telescopes avoid atmospheric aberrations, they are an expensive solution and will still have technical limitations, as the point spread function (PSF) consequence of the finite aperture and light dispersion within the telescope. An image shows the brightness of an object in the spatial domain, i.e., how many photons are coming from a specific location in space. Three properties of an image – size, bright- ness, and resolution – are the most important from a scientific point of view. From size, we learn about astronomical scales. From brightness, we learn the amount of energy that an object is producing, in order to investigate how it is producing that energy. The ability to distinguish one location from a nearby location is called spatial resolution. Higher resolution lets us know things like whether or not two galaxies are merging or if there are two stars close to each other instead of one star by itself. Astronomers aim at having the largest possible images with the highest possible resolution. In addition to their large size, astronomical images have special characteristics: they are commonly stored in Flexible Image Transport System (FITS) digital file format; they have high range of grey values (32-bit float); and they are usually quite noisy. Though images are grey-scale, they contain some colour information because they are taken through a colour filter. Telescopes, instruments and detectors have different sensitivities to different wavelengths and usually work with a well-defined set of filters. These filters can have a variety of widths, from broad-band to narrow-band (∼1000 ˚A to few 10 ˚A). Finally, one particularly important aspect of astronomi- cal image processing is the choice of the stretch function. The representation of the pixel values that one selects has a high impact on the number and shape of the objects that we see in the image. For instance, a logarithmic representation tends to suppress the bright parts of the image and to enhance the fainter ones. This can be desirable though it will reduce the contrast, producing a lower dynamic range. Super-resolution describes a class of methods that can upscale video or images from lower resolutions to higher ones. Such methods have been successfully demonstrated on as- tronomical imaging (e.g. [1]–[4]). Traditionally, interpolation methods such as bilinear and nearest neighbour interpolation are used for upscaling. However, these methods often intro- duce side effects such as noise amplification and blurring. If the PSF can be well determined, deconvolution techniques can be applied to removing the effect of the instrumentation and


CD Bioparticles Provide one-stop customization service of gene therapy for academic and industrial customers.


Vectors of Xylella fastidiosa show pronounced habitat preferences in Corsican agricultural landscapes Mesmin X.; Chartois M.; Rossi J.-P.; Rasplus J.-Y; Cruaud A. CBGP, INRAE, CIRAD, IRD, Montpellier SupAgro, Univ Montpellier, Montpellier, France


НАЦІОНАЛЬНА АКАДЕМІЯ НАУК УКРАЇНИ Інститут енциклопедичних досліджень МЕТОДИЧНІ ЗАСАДИ СТВОРЕННЯ ПАПЕРОВИХ І ЕЛЕКТРОННИХ ЕНЦИКЛОПЕДИЧНИХ ВИДАНЬ Київ 2015


CD ComputaBio is a leading global company providing compelling and novel solutions in computer-aided drug design. We prioritize the integration of our advanced computational capabilities with our extensive expertise in antibody drug design to offer a range of services. These services aim to accelerate drug discovery and development processes by providing our clients with meticulously tailored, reliable, accurate projections while ensuring time and cost-effectiveness. Antibody drug design is an intricate process, entailing the creation of highly specific drugs that target antigens. These drugs are crucial in treating diseases such as cancer, autoimmune disorders, and infectious diseases. CD ComputaBio's antibody drug design services incorporate innovative technologies and advanced computational methodologies, providing our clients with high-accuracy design algorithms to facilitate the discovery and design of the most potent, selective, and safe therapeutic antibodies. Figure 1. Antibody Drug Design.( Muhammed Y, Pius M, Sani B, et al.2021) Antibody Drug Design Services Introduction of Antibody Drug Design Antibody Drug Design & Optimization Our Service


T a r t a r u g a - d e - c o u r o Identificando as 7 espécies de tartarugas marinhas T a r t a r u g a - c a b e ç u d o 5 Placas ao longo da borda do casco 2 garras nas nadadeiras dianteiras cabeça larga cor marrom avermel hada T a r t a r u g a - d e - k e m p 5 Placas ao longo da borda do casco 1 garra nas nadadeiras dianteiras 1-2 garras nas traseiras mandíbula estreita e bico curvo 2 garras nas nadadeiras dianteiras 4 pares de placas sobrepostas no casco T a r t a r u g a - o l i v a cor verde oliva 6-9 placas ao longo da borda do casco casco quase circular 1-2 garras em todas as nadadeiras rem T a r t a r u g a - a u s t r a li a n a casco redondo e achatado borda do casco fina, coberta por cutícula de cera 1 garra em cada nadadeira 4 placas na borda d casco 4 placas ao longo da borda do casco (sem sobreposição) 1 garra nas nadadeiras dianteiras par de estamas na parte dianteira da cabeça 5 cristas ao longo das costas (sem escamas) sem garras couro liso como pele entalhe em forma de dente na mandíbula superior cor preta a azul escuro cor cinza a verde oliva claro Ta rt ar ug a -d e -p en te cor marrom esverdeada escura cor cinza oliva T a r t a r u g a - v e r d e cor marrom (verde no nome se refere à gordura verde) by paige Strudwick for ICrs reefbites ref: fisheries.noaa.gov


Thermodynamic and conformational analysis of the binding of FeIIIZnII - pyrene complexes to DNA Norberto D.R.1; Bortolotto, T.1; Camargo, T.P. 1; Neves, A.2; Terenzi, H.1 1 Centro de Biologia Molecular Estrutural, Departamento de Bioquímica, Universidade Federal de Santa Catarina, 88040-970, Florianópolis - SC,Brazil 2 Laboratório de Bioinorgânica e Cristalograﬁa, Departamento de Química, Universidade Federal de Santa Catarina, 88040-900 Florianópolis - SC, Brazil Metallonucleases have a natural ability for interacting with DNA. Since binding and cleavage of DNA are at the central of action of the cellular transcription and translation, it represents an important target for therapeutic intervention and the development of diagnostic structural probes. In general, metallonucleases bind DNA in a non-covalent interaction fashion, including electrostatic or groove binding, intercalation between base-pairs, and catalysis of DNA cleavage through hydrolytic or oxidative mechanisms. Despite of the progress of recent years in this field, there are many aspects that remain unexplored. This work reports an investigation into the thermodynamic behavior of FeIIIZnII - pyrene complexes interacting with calf thymus DNA (CT-DNA) and a tentative model that aim to explain the properties used in certain families of antitumor agents was developed. The complexes FeZnLAld devoid of pyrene ligands, and FeZnLP1 and FeZnLP2, which are functionalized with one or two pyrene moieties, respectively, were examined by isothermal titration calorimetry (ITC), and compared to UV-Vis and ﬂuorescence spectroscopies. The parameters Kb, ∆Hb and n were determined using a single set of site fittings and indicate that the binding has a positive enthalpy change associated to the substitutions of pyrene, with affinity values from 4.8 x104 M-1 to 1.8x106 M-1. The results show some aspects of intercalation of a planar ligand of the complex in the DNA base pairs stack, with drastic increasing in entropic contribution. The binding free energy ∆Gb was calculated according to different representations and they are in agreement with studies of other heterovalent dinuclear complexes. Our data demonstrate that FeIIIZnII complexes modified with pyrene strongly bind to DNA, and would be important in the development of novel chemical hydrolases capable of DNA targeting and cleavage. Keywords: DNA cleavage, binding affinity, calorimetry, thermodynamics, pyrene Supported by CNPq and CAPES


Search for crop species immune to Xylella fastidiosa subsp. pauca, ST53 Montilon V.1, Cavalieri V.2, Altamura G.2, Zicca S.2, Savino V.1,3, Potere O.1, Susca L.1 1Dipartimento di Scienze del Suolo, della Pianta e degli Alimenti, Università degli Studi di Bari Aldo Moro, Bari, Italy 2CNR, Istituto per la Protezione Sostenibile delle Piante, Bari, Italy 3Centro di Ricerca, Sperimentazione e Formazione in Agricoltura “Basile Caramia”, Locorotondo (Bari), Italy


The 19th Cambridge Workshop on Cool Stars, Stellar Systems, and the Sun Edited by G. A. Feiden Superflare G and K Stars and the Lithium abundance Maria M. Katsova,1 Moisey A. Livshits,2 Tamara V. Mishenina,3 Bulat A. Nizamov4 1 Sternberg State Astronomical Institute, Lomonosov Moscow State University, Moscow, Russia 2 Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of Russian Academy of Sciences, Troitsk, Russia 3 Astronomical Observatory, Odessa National University, Odessa, Ukraine 4 Department of Physics, Lomonosov Moscow State University, Moscow, Russia Abstract We analyzed here the connection of superflares and the lithium abundance in G and K stars based on Li abundance determi- nations conducted with the echelle spectra of a full set of 280 stars obtained with the ELODIE spectrograph. For high-active stars we show a definite correlation between log A(Li) and the chromosphere activity. We show that sets of stars with high Li abundance and having superflares possess common properties. It relates, firstly, to stars with activity saturation. We consider the X-ray data for G, K, and M stars separately, and show that transition from a saturation mode to solar-type activity takes place at values of rotation periods 1.1, 3.3, and 7.2 days for G2, K4 and M3 spectral types, respectively. We discuss bimodal distribution of a number of G and K main-sequence stars versus an axial rotation and location of superflare stars with respect to other Kepler stars. We conclude that superflare G and K stars are mainly fast rotating young objects, but some of them belong to stars with solar-type activity. At the same time, we found a group of G stars with high Li content (log A(Li) = 1.5 −3), but being slower rotators with rotation periods > 10 days, which are characterized by low chromospheric activity. This agrees with a large spread in Li abundances in superflare stars. A mechanism leading to this effect is discussed. Keywords: Stars: activity – Stars: coronae – Stars: rotation – Stars: flares – Stars: abundances 1 Introduction One of the most important results of study of activity of low-mass stars is a detection with the Kepler mission of su- perflares whose total energy in optics and near IR-range is 1033 −1035 ergs, that is by 2–4 orders of magnitudes more than the total energy of the largest flares on the Sun. What distinguishes the stars where such cataclisms can occur? This problem is solved in two ways; first is determination of fundamental parameters and flare occurrence frequencies. This was fulfilled by Maehara et al. (2012) and Notsu et al. (2015a, b) where they found that these events are typical for G and partly K stars, which rotate faster than field stars and are more magnetically active. Another way is comparison of general properties of superflare stars with distinctive fea- tures of other kinds of active late-type stars. This is com- parison of activity at different layers of stellar atmospheres. Messina et al. (2003) were the first who have analyzed rota- tional modulation of the optical continuum caused by spots and the X-ray fluxes of stars of different spectral types. Lately new X-ray data and observations of optical variability of many late-type stars with the Kepler misson have appeared. Recently we considered a possibility of occurrence of very powerful events on late-type stars in the frameworks of cur- rent ideas on solar flares (Katsova and Livshits, 2015). Wich- mann et al. (2014) Şstarted a programme to study the nature of the stars on which these super flares have been observed.Ť Here we are trying to analyze features of those stars, where such extremal phenomena occur, on the base of new results of multiwavelength observations of late-type stars. 2 Where do Superflares Occur? As an example, let us consider a restricted set of Kepler’s stars where superflare light curves were registered with the higher temporal resolution (1 min). We use data for 83 active late-type dwarfs fro


The ASTAROTH project An innovative light detector based on Silicon PhotoMultipliers for rare event physics and its applications in dark matter direct detection experiments Valerio Toso1,2, for the ASTAROTH collaboration NuPhys2023: Prospects in Neutrino Physics 18–20 December 2023 King's College London 1Università degli Studi di Milano; 2INFN Milano


Reseña y meditación de la primera Novela Moderna: El Ingenioso Hidalgo Don Quijote de la Mancha Un dramaturgo, poeta y novelista español, autor de la novela El ingenioso hidalgo don Quijote de la Mancha, considerada como la primera novela moderna de la literatura universal, Miguel de Cervantes Saavedra fue dramaturgo, poeta y novelista español. Tuvo una vida azarosa de la que poco se sabe con seguridad. La fecha exacta de su nacimiento no se ha podido averiguar, de igual modo su fecha exacta de su fallecimiento; por el contrario, se sabe que este fue bautizado el 9 de octubre de 1547. De su muerte tan solo se supone que podría haber sido el 29 de septiembre. En 1606, la familia se mudó a Madrid. Miguel de cervantes, ya prestigioso novelista y escritor, fue redactando entonces gran parte de su producción literaria, aprovechando títulos y proyectos viejos. Tras ocho años de silencio editorial desde la publicación de la novela que lo inmortalizaría, publicó numerosas obras, una verdadera avalancha literaria. En su obra El ingenioso Hidalgo Don Quijote De La Mancha, que fue publicada en 1605 se ilustra el conflicto entre la justica idealizada de Don


Fostering open science practices through OpenUP: the role of project work in open science policy implementation Vilte Banelytė, Vilius Stančiauskas, Edit Görögh LIBER 2019, poster presentation


! ! ! For Participatory Enquiry and Action Activities • In this 10 credit undergraduate course, students evaluate how consumer brands can be profitable and sustainable. Students work in consultancy teams on live client projects for Fast Moving Consumer Goods (FMCG) brands in luxury, beverage, and fashion markets to analyse the marketplace challenges and produce creative recommendations on how to increase sustainability whilst balancing profitability. • This course is delivered through blended learning with a combination of online active learning sessions, practitioner workshops, online activities and on campus small group tutorials. Students produce a group project for one client and compete to pitch their recommendations to the clients at a Dragons Den event. • This course provides students with the opportunity to work on a real-life sustainability challenge for an external organisation by playing the role of a marketing consultant. It tasks students to analyse and overcome the main barriers of embedding sustainability goals across their business to envision sustainable opportunities. CoDesignS ESD - is licensed under a CC BY-NC 4.0 - http://codesignsesd.org/ How the SDGs targeted were embedded The learner understands how complex supply chains create barriers and opportunities to sustainable marketing practice. The learner analyses the role businesses play in creating sustainable cities and communities. The learner produces recommendations for responsible consumption and production informed by research and evidence. How were the activities designed and delivered? Participatory enquiry and action activities Practitioner-led workshops that brief students on the client projects in preparation for the group report. Small group tutorials Students work in small group tutorials on tasks and present findings for the group project and receive formative feedback on their work from tutors. Presentation skills Students undertake an asynchronous week-long training course on presentation skills and receive formative feedback with presentation coaches. Marketing Sustainably Dr Stephanie Anderson, Dr Nilay Balkan & Dr Thomas Anker Adam Smith Business School UKPSF: A1-A4; K1-K4 Photo by Campaign Creators on Unsplash How the specific learning objectives were targeted By the end of the module the students were able to: • Analyse the levels of the marketing environment and their impact on decision- making for sustainable business practice • Produce creative and persuasive marketing communications strategy and tactics that communicate brand sustainability • Work effectively in groups to deliver a marketing project that responds to current sustainability trends in marketing practice How the specific learning objectives were assessed • A group report in which students were tasked to analyse brand propositions and produce recommendations how to enhance sustainability for their client brand. • A formative verbal group presentation that communicates the main findings and recommendations of group report. • An individual poster that tasks students to produce a set of creative recommendations to reposition the client’s brand in response to changing consumer behaviours.


Colección de ESMOS 1 Termozimas proteasas como fuente de interés industrial Olíblish Mariel Laguna Morales* iD Licenciatura en Biotecnología, Facultad de Ciencias Biológicas, Benemérita Universidad Autónoma de Puebla, Puebla, México. *Email: oliblishlaguna@gmail.com 21 de Noviembre de 2022 DOI: http://doi.org/10.5281/zenodo.7340677 Editado por: Jesús Muñoz-Rojas (Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla). Revisado por: Ligia Catalina Muñoz-Arenas (Facultad de Ingeniería Ambiental, UPAEP Universidad, Puebla, Puebla, México). Colección de ESMOS Resumen Gracias a la ciencia, poco antes de iniciar el siglo XXI, empezaron a descubrir microorganismos que viven en lugares en los cuáles no se imaginaba posible, organismos que han colonizado lugares donde se marcan los límites para otros. rompiendo y cambiando los parámetros previamente establecidos para asegurar que había vida como la


VARFISH: COMPREHENSIVE DNA VARIANT ANALYSIS FOR DIAGNOSTICS AND RESEARCH Manuel Holtgrewe, Oliver Stolpe, Mikko Nieminen, Stefan Mundlos, Alexej Knaus, Uwe Kornak, Dominik Seelow, Lara Segebrecht, Malte Spielmann, Björn Fischer-Zirnsak, Felix Boschann, Ute Scholl, Nadja Ehmke, Dieter Beule recently published as Holtgrewe, Manuel, et al. "VarFish: comprehensive DNA variant analysis for diagnostics and research." Nucleic Acids Research (2020): gkaa241.


A Toolkit for Reproducible Big Data Analytics in the Cloud 2022 ESIP January Meeting Xin Wang (xinwang11@umbc.edu), Jianwu Wang (jianwu@umbc.edu) University of Maryland, Baltimore County


SLOVAK and CZECH GLASS CONFERENCE & seminar on DEFECTS in GLASS Trenčianske Teplice June 28 – 30, 2017 BOOK of ABSTRACTS


MqsR-dependent regulon of Xylella fastidiosa modulates stress tolerance and persister cell formation Carvalho, I.G.B.1, Merfa, M.V. 2, Teixeira-Silva, N.S.1, Martins, P.M.M.1, Takita, M.A.1, and De Souza, A. S.1 1 Centro de Citricultura Sylvio Moreira Agronomic Institute (IAC), Cordeirópolis, SP, Brazil. 2 Department of Entomology and Plant Pathology, Auburn University, Auburn, AL, United States.


AMERICAN JOURNAL OF EDUCATION AND LEARNING ISSN: 2996-5128 (online) | ResearchBib (IF) = 9.918 IMPACT FACTOR Volume-2| Issue-5| 2024 Published: |30-12-2024| 1008 THE EFFECTIVENESS IN IMPLEMENTATION OF MNEMONICS TECHNIQUES IN TEACHING ENGLISH VOCABULARY https://doi.org/10.5281/zenodo.14544157 Alikberova Kamila Adkhamovna The Uzbek State World languages University, teacher Abstract The teaching and acquisition of English vocabulary remain critical components of language learning. Mnemonic techniques, which utilize associations, imagery, and structured recall, offer innovative methods to improve vocabulary retention and recall. This article examines the effectiveness of mnemonic strategies in teaching English vocabulary, focusing on their impact on learners' performance, memory retention, and engagement. By analyzing various techniques such as keyword methods, imagery associations, and acronym-based learning, the study explores the benefits and challenges of integrating mnemonics into educational settings. Key Words mnemonics, English vocabulary, teaching methods, memory techniques, language acquisition. INTRODUCTION: Vocabulary is the foundation of language learning, facilitating communication and comprehension. However, vocabulary acquisition often poses challenges for learners due to the vast number of words and their contextual nuances. Traditional rote memorization methods, though widely used, frequently fail to yield long-term retention, leading educators to explore innovative strategies. Mnemonic techniques, which rely on mental associations and cognitive linking, offer promising alternatives. By transforming abstract words into meaningful, memorable patterns, mnemonics can significantly enhance vocabulary retention and recall. This article investigates the implementation of mnemonic methods in teaching English vocabulary, focusing on their practical applications, effectiveness, and potential challenges. Objectives of the study include: 1. Evaluating the impact of mnemonic strategies on vocabulary retention. 2. Exploring different mnemonic techniques used in teaching English vocabulary.


A Magnetised High-Pressure Gaseous Argon TPC for the DUNE Near Detector NuPhys 2023 King’s College London 18.12.2023 Francisco Martínez López for the DUNE collaboration f.martinezlopez@qmul.ac.uk


TÚ Y YO, ¿QUÉ PODEMOS HACER? LUCÍA FERNÁNDEZ CELORIO ÁLVARO MORAIS BERNARDO KORI CORUJO ÁLVAREZ VANESA ROMÁN DÍAZ DANIELA GARCÍA ÁLVAREZ


December 12-16, 2021 Jeju Island UNESCO Global Geopark, Republic of Korea 2021.12.12.-16, 제주도 유네스코 세계지질공원 " # 4 5 3 " $ 5  # 0 0 , 제9차 유네스코 세계지질공원 제주 총회


See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/320058238 Public perception foresters of invasive ash dieback pathogen arrival in Serbia Conference Paper · September 2017 CITATIONS 0 READ 1 1 author: Some of the authors of this publication are also working on these related projects: PONTE Project H2020 View project Ljiljana Keca University of Belgrade, Faculty of Forestry, Belgrade, Serbia 123 PUBLICATIONS 101 CITATIONS SEE PROFILE All content following this page was uploaded by Ljiljana Keca on 27 September 2017. The user has requested enhancement of the downloaded file.


https://chaire-bea.vetagro-sup.fr/en/ June 2023 Species sheet – All about dogs! Author: Chaire BEA Contributing authors: Caroline Gilbert, Claire Diederich, Luc Mounier, Estelle Mollaret Graphics: Marion Weisslinger DOI : 10.5281/zenodo.12912873 You love dogs and want to know more about them, their communication signals, cognitive abilities and the way they perceive the world? Find out more in this new species sheet! This species sheet was produced with the support and proofreading of Caroline Gilbert, veterinarian, ethologist and professor at the Ecole Nationale Vétérinaire d’Alfort and Claire Diederich, veterinarian, ethologist and professor at the University of Namur.


By Sarah Howell 7th International Conference on Women in Physics 11th-16th July 2021 https://wp.csiro.au/icwip2020/ Hold online as a virtual conference at Whova.com/web/icwip_202109 Hosted by the Australian Institute of Physics


Abstract Type: Poster Abstracts Abstract Status: Complete Abstract ID: 826054 Abstract Title: Global Search Trends: Geographic and Temporal Disparities in the Relative Search Volume for Orofacial Pain Types Authors: Junhel Dalanon, DMD, MAT, EdD; Arief Waskitho, Drdrg, SpProsK; Parimal Chavan, BDS; Swarna Lakshmi, BDS, MDS; Yoshizo Matsuka, DDS, PhD Background and Aims In the information era, seeking health information from search engines is not uncommon. These search trends or relative search volumes (RSV) have been used in the past to evaluate and forecast epidemics. This study aimed to evaluate the variations of the searches for orofacial pain types from 197 countries in a decade using Google Trends (GT). Methods A search query was done with the parameters Worldwide as location, January 1, 2010- December 31, 2019 as time range, Health as category, Web Search as database, and the search terms tooth pain (TP), jaw pain (JP), face pain (FP), head pain (HP), and mouth pain (MP) were used. Comma-separated value files were downloaded from the internet and analyzed. Search trends were expressed as RSV or the maximum popularity rate in a given search term, place, and time. Results The results of a two-way ANOVA found substantial differences on the RSV for types of pain, F (26, 1215) = 39.47, p< 0.001. Out of the 27 countries that elicited a response, HP was found to be significantly higher than any other orofacial pain type in India, Ireland, Kenya, Pakistan and South Africa. A Brown-Forsythe and Welch ANOVA found considerable disparities in search trends for various types of pain, F (4, 21) = 40.86, p< 0.001. A Dunnett’s T3 multiple comparisons test revealed that the RSV for JP (29.2±2.1, p< 0.001), FP


Student Festival of “Kavoshgarane Aseman” (explorers of the sky) Mehr observatory-IRAN Hassan Baghbani Fatemeh Hasheminasab, Mahdi Rokni, Elham Rajaei, Fatemeh Baghbani, Mina Someilipour, Ayda Rajaei, Ameneh Jamali www.skylian.org Hasan.baghbani1971@gmail.com


Looking for evidence of independent researchers in bibliographic records: an exploration Eline Vandewalle* and Camilla Lindelöw** *Eline.Vandewalle@uantwerpen.be https://orcid.org/0000-0002-9852-3373 Centre for Research and Development Monitoring (ECOOM), University of Antwerp, Belgium ** camilla.lindelow@hb.se https://orcid.org/0000-0002-3331-0940 Swedish School of Library and Information Science, University of Borås, Sweden Abstract Independent researchers or scholars have always (co-)existed with academic professionals. The term independent researcher has been used to refer to various phenomena at different times - from the historical researchers pursuing their research interests independently to today's researchers struggling to find permanent positions or funding. Bibliographical data sources offer a possibility to learn more about these researchers, but they do not provide a full picture. In this exploratory study, we compare three different data sources: Web of Science, Scopus and OpenAlex. All three sources show an increase in records associated with independent researchers, and the amount of records varies. We use OpenAlex to further explore publications by independent researchers active in the Social Sciences and Humanities (SSH). We provide an overview of the topics and the forms of open access publishing. We also explore different career trajectories based on the full publication history of independent researchers. 1. Introduction While most scholarly publications today are authored by people affiliated with research organisations, some are (co-)authored by ‘independent’ or ‘unaffiliated’ researchers. These authors are active in research but are not employed by an organisation to do research. There may be many reasons for this. The history of research has been marked by a move towards professionalisation, whereby research has been increasingly pursued within the confines of academic organisations and controlled by scientific societies. At the same time, we can still find examples of independent researchers publishing their work outside of the academic system. Independent researchers are certainly a very diverse group, from the historical cliché of the gentleman scientist, to women excluded from the academy, to people trying to continue research in an academic world of high competition and few stable job opportunities, to the professor emeritus continuing to work in retirement. Independent researchers have been described as a ‘hidden intelligentsia’ in society (Flesch, 1997). Orlans (2002, p. 12) defines ‘Independent Scholars’ as follows: ‘In various definitions, independent scholars are those unaffiliated with an academic, or with any, institution, or whose work duties do not include research and scholarship. Typically, they are Ph.D.s in the humanities, often women, who, unable to find scholarly employment ("independent," a wit says, is a euphemism for "unemployed"), pursue


Nat J EU SAL The Role of National Judges in the Enforcement of EU State Aid Law First Residential Seminar University of Murcia May 30th – 31st 2019 NatJEUSAL is an action co-funded by the European Commission, Directorate General for Competition, and the University of Padova, Department for Public Law, International and EU Law - DiPIC Main scientific partners are the Faculties of Law of the Universities of Murcia and Würzburg Further scientific partners are National University of Ireland Maynooth Department of Law, Riga Graduate School of Law, University of Zagreb Faculty of Law Session I DATE TOPIC TIME PROFESSOR 30 May Introduction 16:00 – 16:10 Juan Jorge Piernas López and Bernardo Cortese Universidad de Murcia/University of Padova 30 May Article 107(1) TFEU The notion of State aid 16.10 – 16.50 Aindrias Ó Caoimh Former Judge of the Court of Justice of the European Union 30 May Article 107(2) and (3) authorized aid 16.50 – 17:30 Delia Ferri Maynooth University BREAK 17:30 – 18:00 30 May The State Aid Tax Cases: A Practical and a Philosophical Perspective 18.00- 18.40 Vincent Power A&L Goodbody 30 May Discussion /sharing experiences 18:40 – 19:20 Marie Baker Court of Appeal, Ireland