Archaeological Subsurface Survey of Lighthouse Archaeological Subsurface Survey of Lighthouse Archaeological Subsurface Survey of Lighthouse P i t S th El th B h Point South Eleuthera Bahamas Point, South Eleuthera, Bahamas T cker Beckett Brigid Carr Charlie Fichtner Tucker Beckett, Brigid Carr, Charlie Fichtner, Rachael Pridmore, Sarah Sasek, and Daisy Spencer Rachael Pridmore, Sarah Sasek, and Daisy Spencer Advisors: Justin Symington Gabe Wofford Taylor Fargo and Francesca Perkins Advisors: Justin Symington, Gabe Wofford, Taylor Fargo, and Francesca Perkins Introduction Methods Introduction Methods An X and Y axis was created (see The Lucayans were a group of An X and Y axis was created (see figure 2) in order to establish waypoints people who migrated from Venezuela to figure 2) in order to establish waypoints where test pits would be dug for a sub- the Bahamas from the years of 2100 where test pits would be dug for a sub surface survey BCE to 500 CE. (see Figure 1) They surface survey. maintained residence there for about 1000 1000 years, until they came into contact i h C l b d hi i 1492 with Columbus and his men in 1492. Th i l ti k d t 40 000 di d Their population peaked at 40,000 died t ithi 20 Si th L out within 20 years. Since the Lucayans h d itt d th i littl Li hth had no written records, there is very little k b t th i lt Th h Lighthouse known about their culture. There has b h l i l k d i Lighthouse Bay g Road been some archaeological work done in th B h hi h h b f d Lighthouse Bay Road the Bahamas which has been focused i l i th i l d N mainly in the islands New P id S S l d d T k Providence, San Salvador, and Turks d C i t th i till h t and Caicos; yet, there is still much to learn. Th f thi t d t The purpose of this study was to t i th t f th P ascertain the nature of the Pre- C l bi t Li hth P i t Lighthouse Fi 2 Colombian usage at Lighthouse Point. Thi it h ff h d Lighthouse Figure 2 This site has offshore cays and ca es hich are closel associated ith Point caves, which are closely associated with Lucayan religious and ceremonial Steps to a Sub Surface Survey Lucayan religious and ceremonial traditions In addition there are reefs Steps to a Sub-Surface Survey traditions. In addition, there are reefs nearby to provide food and sandy nearby to provide food, and sandy beaches which would have made a good Excavate: beaches which would have made a good area to land canoes This information led Each test pit was a Soil Profile from Soil Profile from area to land canoes. This information led the archaeology team to hypothesize Artifacts by Areas Each test pit was a circle with a 50 Soil Profile from Li hth R d Soil Profile from the archaeology team to hypothesize that the Lucayans used Lighthouse Point 0 10 y circle with a 50 centimeter diameter Lighthouse Road Lighthouse Point that the Lucayans used Lighthouse Point for religious and ceremonial purposes 0-10 centimeter diameter and averaged 80 g for religious and ceremonial purposes. 10-20 a d a e aged 80 centimeters deep. 20-30 p Every 10 30-40 M y centimeters, dirt is 40 50 30 40 n C , removed from the 40-50 h in Lighthouse Road pit. 50-60 pth Lighthouse Road Li hth B p 60-70 Dep Lighthouse Bay 70-80 D Lighthouse Point Sift 80 90 70-80 Sift: 80-90 The dirt and 90-100 materials were 0 10 20 sifted through a 0 10 20 one quarter inch Number of Artifacts screen. Figure 3 Figure 4 Fi 5 Fi 6 Figure 3 Figure 4 Figure 5 Figure 6 Fi 1 Figure 1 Results Discussion Record: Results The majority of the materials found at Discussion We found no conclusive evidence of Lucayan Finally, our findings Literature Cited The majority of the materials found at Lighthouse Point were ecofacts and fire affected We found no conclusive evidence of Lucayan habitation or activity at Lighthouse Point However the y, g were recorded. Carr, Robert et Al. An Archaeological and Historical Assessment of Preacher's Cave Eleuthera Bahamas AHC Bahamas Technical Report Lighthouse Point were ecofacts and


An International Plant Sentinel Network as an early-warning system; research on future pest threats (IPSN II) Funding Mixed funding mechanism: Non-competitive and virtual pot. Each funder only pays for the participation of their own national researchers, in certain cases after national selection. Total funding € 440 000 ca. Picture 1 Picture 1 Picture 1 Goals The IPSN’s overall goal is to act as an early warning system for new and emerging plant pests and diseases; providing information that can help mitigate the impacts of such organisms or prevent their introductions altogether. In order to do this, the IPSN will utilise its already established network of botanic gardens, arboreta, plant protection scientists and National Plant Protection Organisations (NPPOs) as well as the tools and resources developed in the previous project. Research consortium DEFRA (GB), BMLFUW (AT), FPS (BE), CISTA (CZ), BMEL (DE), CREA (IT), SASA (GB), APHIS (USA), UNITUS (IT), UdL (ES), PHA (AU), UCPH (DK), CABI (GB), BBB (NZ), SLU(SE), CABI (CH), SDU (TR) Contact information Project coordinator: Katherine O’Donnel katherine.odonnell@bgci.org Key outputs and results • Key training and standardised surveying materials aimed at supporting garden staff with the opportunity to explore utilisation by a wider range of stakeholders. • European and international workshops in Euphresco partner countries and prioritised areas around the world. • Best practice and general support for botanic gardens and arboreta wishing to run citizen science projects or education programmes. • An electronic reporting system and front-facing database to track changes in plant health and gather information to enhance early detection and/or risk assessments. • Maps illustrating the distribution of gardens, host species and pest species. • Sentinel research projects for priority organisms and priority host species. Objectives • Enhanced early detection of new and emerging pests and diseases; including known and unknown organisms. • The project will support Pest Risk Analysis (PRAs) through research coordination and evidence gathering to address knowledge gaps to support PRA activities. • The establishment of a self-sustainable network. 01/2017-12/2019


Renewable Energy Generation Expansion Pathways for Cameroon Yvan Ayuketah, Marilyn Bongmo 1 Regional Center for Energy and Environmental Sustainability (RECEES), Ghana. 2 Ministry of Water Resources and Energy, Cameroon 1. Context Contact: Yvan Ayuketah: yvanayuketah@gmail.com ; Marilyn Bongmo:bimewoman1gmail.com 5. Policy insights, conclusions and future work 3. Methods & Scenarios 2. Aim • Cameroon has a population of 25.88 million and GDP of $39.50 billion in 2020 [1]. • The nation aims to reduce its dependence on hydropower and diversify its energy mix. • its Nationally Determined Contributions (NDCs) aim to reduce emissions by 32% in 2035 [3]. • With developmental goals greatly hindered by inadequate power generation, the nation seeks increase thermal generation and renewables to increase its 70% access rate [4]. • Cameroon aim to ensure a 25% share of renewables in the generation mix by 2035. This would also increase energy its security [5]. • The OSeMOSYS, an open-source integrated least-costs energy model was used with clicSAND as the modelling interface. • The key assumptions and data sources were gotten from [4] • Modelling period was from 2020 to 2050 • Three scenarios were developed for Cameroon: (i) The business-as-usual (BAU) • No obligation to meet the energy diversity, RE and other energy sector targets in masterplans such as Vision 2035, the Development Project of the Energy Sector (PDSEN) and the Rural Electrification Master Plan (REMP) [4]. • No constraints on generation system emissions. (ii) NDC scenario • 25% and 45% RE target by 2035 and 2045 respectively • Reduced dependence on hydropower • No constraints on emissions (ii) Net-zero scenario • Zero electricity sector emissions by 2050. • Reduced dependence on hydropower. 4. Results 6. References • To evaluate the least-cost optimal generation expansion pathway up to 2050 for Cameroon under current trends and no policy intervention. • To determine the optimal generation expansion pathway that attains a 25% and 45% renewable energy share by 2035 and 2050 respectively. • To evaluate the optimal generation expansion pathway for Cameroon that achieves net-zero emissions by 2050. Conclusions: • Continuous reliance on Hydropower for over 75% of generation mix in the BAU scenario, • The 25% RE target in the NDC is not enough to reduce dependence on hydropower. However, attaining a 45% target by 2050 significantly reduces this dependence. • Its possible to transition to net-zero in Cameroon due to the small contribution of fossil fuels Policy insights • An intervention is needed to reduce Cameroon’s dependence on hydropower for increased energy security. • Priority and incentives should be allocated to renewables. This would enable them phase out fossil fuels in the generation mix. Future work • Asses the flexibility of power system under higher penetrations of RE. • Investigate the impact on increased RE penetration on the stability an reliability of the power system. • Investigate the impact of carbon pricing and emission trading in the power system. JOINT SUMMER SCHOOL ON MODELLING TOOLS FOR SUSTAINABLE DEVELOPMENT | 2022 Figure: The map of Cameroon. Source [4] A Cost-benefit analysis of Policy, Programs and Projects (C3PO) that is Retrievable, Reusable, Repeatable, Reconstructible, Interoperable and Auditable (u4RIA) [1] World Bank, "Cameroon Development Indicators," The World Bank Group, 2022. [Online]. Available: https://data.worldbank.org/country/cameroon. [Accessed 9 June 2022]. [2] MINEPDD, "Intended Nationally Determined Contribution (INDC)," 29 July 2016. [3] IEA, "World Energy Outlook 2020," International Energy Agency, Paris , 2020. [4] KEEI, "A Study for Establishment of the Master Plan of Renewable Energy in Cameroon" Korea Energy Economics Institute, Ulsan, 2017. [5] Allington, et al, "Selected ‘Starter Kit’ - Energy system modelling data for Cameroon (#CCG)," Research Square, pp. 1-15, 2021 0 50 100 150 200 250 2015 2016 2017 2018 2019 2020 2021


Research data services in academic libraries: the essential list Ana Doñate-Cifuentes1, Fernanda Peset2, Antonia Ferrer-Sapena2, Consol García3 1Universidad CEU Cardenal Herrera, València, Spain; 2Universitat Politécnica de València, Spain; 3Universitat Politécnica de Catalunya-Barcelona Tech, Spain; consol.garcia@upc.edu Our objective: study about research data services in this type of library settings (America and Europe). Previously, the Carol Tenopir’s team reviews the situation in North America and Canada. The aim of our work is to build a list with the essential data services for the small libraries with a little budget, and describe the European situation. Acknowledgements: Wolfram Horstmann, Carol Tenopir, Imma Subirats and Eulàlia Serveto. Conclusion: The three essential services that all the academic libraries must offer as default are: consulting with faculty, staff or students on data management plans and metadata standards, and preparing data sets for deposit into a repository. Method: select the best institutions by bibliography and expert opinion, and the medium by regional criterion and DOAR review; check their web sites looking for the RDS; classify them by Tenopir’s team work. Consulting with faculty, staff or students on data management plans (costs, standards, storage...) Consulting with faculty, staff or students on data and metadata standards. Preparing data / data sets for deposit into a repository (formats, organizing, documentation, legal aspects, integrity,...) Providing technical support for research data services (RDS) systems (e.g., a repository, access and discovery systems) where can I release my data? Providing reference support for finding and citing data / data sets. Creating web guides and finding aids for data / data sets / data repositories. Identifying data / data sets that could be candidates for repositories on or off campus Creating data or transforming metadata for data or data sets. Discussing research data services (RDS) with other librarians, or other people on campus, or RDS professionals on a semiregular frequency. Deaccessioning / deselection of data / data sets for removal from repository Outreach and collaboration with other research data services (RDS) providers either on or off campus. Directly participating with researchers on a project (as a team member). Training coworkers in your library, or across campus, on research data services (RDS). 0000-0001-5708-8902 0000-0001-6432-917X 0000-0003-3706-6532 0000-0001-8085-0088 10 services 8 services 8 services 8 services 7 services 6 services 6 services 6 services 6 services 2 services Expert criterion: DOAR criterion: 6 services 5 services 4 services 3 services


Eleanor J. Junkins1, Katharine M. N. Lee2, & Kathryn B. H. Clancy3,4 1 Department of Psychology, College of LAS, UIUC; 2 Division of Public Health Sciences, Washington University in St. Louis; 3 Department of Anthropology, UIUC; 4 Beckman Institute, UIUC Enhancing Knowledge through Engagement: Participation in an Unpaid Survey-Based Health Research Acknowledgments This research was supported in part by the University of Illinois Beckman Institute for Advanced Science and Technology, the University of Illinois Interdisciplinary Health Sciences Institute and the University of Illinois Center for Social & Behavioral Science Small Grant Program. Contact Me junkins2@illinois.edu References 1. Borno, H., Siegel, A., & Ryan, C. (2016). The problem of representativeness of clinical trial participants: Understanding the role of hidden costs. Journal of Health Services Research & Policy, 21(3), 145–146. 2. Kennedy-Martin, T., Curtis, S., Faries, D., Robinson, S., & Johnston, J. (2015). A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results. Trials, 16(1), 495. 3. Gobat, N. H., Gal, M., Butler, C. C., … & Nichol, A. (2018). Talking to the people that really matter about their participation in pandemic clinical research: A qualitative study in four European countries. Health Expectations, 21(1), 387–395. 4. Chin, L. J., Berenson, J. A., & Klitzman, R. L. (2016). Typologies of Altruistic and Financial Motivations for Research Participation: A Qualitative Study of MSM in HIV Vaccine Trials. Journal of Empirical Research on Human Research Ethics, 11(4), 299–310. 5. Sober, E. (1988). What Is Evolutionary Altruism? Canadian Journal of Philosophy Supplementary Volume, 14, 75–99. https://doi.org/10.1080/00455091.1988.10715945 6. Lee, K. M., Junkins, E. J., Fatima, U. A., Cox, M. L., & Clancy, K. B. (2021). Characterizing menstrual bleeding changes occurring after SARS-CoV-2 vaccination [Preprint]. Obstetrics and Gynecology. 7. R Core Team. (2022). R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing. 8. Silge, J., & Robinson, D. (2016). tidytext: Text Mining and Analysis Using Tidy Data Principles in R. JOSS, 1(3). 9. Hvitfeldt, E. (2020). textdata: Download and Load Various Text Datasets. 10. Grün, B., & Hornik, K. (2011). topicmodels: An R Package for Fitting Topic Models. Journal of Statistical Software, 40(13), 1–30 Conclusions It is evident that people found the survey through a variety of means and trusted sources. Many described googling for their symptoms and found our study. Altruistic motives, including existential, vernacular, and political, were apparent from this analysis. The implication of this work is that responsive, flexible post-clinical trial survey research with lower barriers of participation may be possible and may be able to reach people more widely. It may also serve to create active communication between scientists and the public to keep everyone informed of post-vaccine experiences. Future clinical trial research can be informed by attention to the large range of symptoms experienced by people. Aims 1) How did people hear about the study? 2) What were people’s interest in the study? 3) How do these interests relate to altruistic motivations of participation? Data Survey Instrument Demographics include age, country of birth, gender, race, and ethnicity. Open-ended text responses: • How did you hear about this project? • What is your interest in this project? Sample Data was derived from a large, online mixed-methods survey on menstruation and vaccine side-effects following COVID-19 vaccination6 (N~102,000). The current sample was limited to people in the USA who responded to both these questions in English. • N= 22,737 • Age M=33.7 years (SD=9.8) • 90.4% cisgender women; 83.4% white; 81.6% non- Hispanic Introduction Health research—and more specifically clinical trials for vaccines—is oft


Most biological models are composed of single-compartment neurons. Despite recent ﬁndings on dendritic computational properties, these features have been only rarely exploited [1]. We introduce a multi-compartment model for pyramidal neurons [2], in which bursts and dendritic input segregation allow for biologically plausible target-based learning [3]. The solution of a problem is represented as a spatio-temporal pattern of bursts, suggested to apical tufts of neurons. A store-and-recall and a nontrivial navigation tasks are learned, the latter by introducing a hierarchical architecture of layers enabling the decomposition into simpler subtasks (hierarchical imitation learning) [2]. Acknowledgements This work has been supported by the European Union Horizon 2020 Research and Innovation program under the FET Flagship Human Brain Project (grant agreement SGA3 n. 945539) and by the INFN APE Parallel and Distributed Computing Laboratory. References [1] Payeur, Guerguiev, Zenke, Richards, Naud. Nature neurosci. (2021) 24, 1010. [2] Capone, Lupo, Muratore, Paolucci. arXiv (2022) 2201.11717. [3] Muratore, Capone, Paolucci. PloS one (2021) 16(2), e0247014. Cosimo Lupo*,1, Cristiano Capone*,1, Paolo Muratore2, Pier Stanislao Paolucci1 1 INFN, Sezione di Roma, Rome, Italy — 2 SISSA, Trieste, Italy. * These authors contributed equally to the work. Burst-dependent plasticity and dendritic ampliﬁcation support target-based learning and hierarchical imitation learning Coincidence mechanism • Somatic spikes open a window • Apical spikes within the window create the coincidence • Result is a burst activity Store-and-recall task • Learn a target 3D trajectory • After many presentations: - Internal bursting activity spontaneously reproduced - Accurate output (mse ~10-2) Target-based learning Soma+distal internal bursting activity is the target, soma+proximal bursts have to reproduce it: Multi-compartment pyramidal neuron • Dendritic segregation • Apical proximal compartment for recurrent synapses from other neurons • Apical distal compartment for target and context signals Apical context as target selector • Desired target is selected by the context • Successful target recover even after apical context switch-off or corruption through noise • Basal context has no such robustness Hierarchical architecture • High network: - task-selecting output as context for low network • Low network: - task-actuation output, selected by injected context Hierarchical imitation learning • Manager/worker architecture is able to solve the task • High network learns which task to solve • Low network learns how to reach the target (button or food) • Learning on ~100 button/food examples Performances • Test is done in closed loop • Button reaching rate ~100% • Apical context crucial for hierarchical decomposition (basal context not able to properly assign the task) Button-and-food task • First reach the button and unlock it; then reach the food • Reaching food in ﬁrst place gives no reward • Button/food positions are random Contacts Email: cosimo.lupo89@gmail.com Conclusions • Target-based learning is an alternative to error-based approaches, offering several advantages • Bursts and dendritic segregation naturally support it • Target-based learning also allows to successfully implement hierarchical policies boosting Hierarchical Imitation Learning Future outlooks • Effects of sleep (replay of burst patterns and performance improvement) arXiv preprint Accepted in ICML 2022


@M4ESTRO_Project M4ESTRO EU Project www.m4estro-project.eu Technology Transfer Syst Resilient, transparent and flexible manufacturing processes in value chains A holistic framework based on 4 pillars Resilient equipment, AI and trusted data for adaptive manufacturing Resilient Simulations to the Industrial Metaverse for responsive manufacturing Human centered Manufacturing Resilience and Sustainability 17 Partners - 8 Countries - 42 Months – 6 Million Euros in funding Strategies and models for flexible, resilient, and reconfigurable value networks through Trusted and Transparent Operations Industrial Manufacturing As a Service


Participación e involucramiento de madres de preescolares cuando usan conjuntamente dispositivos móviles. PhD(c) Rodrigo Arroyo (rarroyob@udd.cl) Doctorado en Ciencias del Desarrollo y Psicopatología Estudio Dos Situación experimental Introducción N=30 díadas EG Lúdico Contexto inducido El uso conjunto (Joint media engagement, JME10) refiere a los momentos cuando 2 o más personas (la madre e hijo/a) se acompañan y comparten mientras alguno de los dos (o ambos) ve, reproduce, busca, lee, juega o crea en el dispositivo. La evidencia sugiere que JME es una forma de aumentar el impacto positivo derivado de dicho uso, tanto para el desarrollo de los niños como para la relación entre madres e hijos. 11,12,13,14 Reportes internacionales muestran que las instancias JME se desarrollan principalmente en medios tradicionales (TV, libros), con un 63% de padres que refieren JME-DM15. Al explorar los predictores de JME-DM, se han analizado las características sociodemográficas (edad, educación), uso y experiencia de uso materna de DM5, junto con el sistema de creencias que enmarca y se traduce en las prácticas parentales16,18,19. La evidencia muestra una fuerte relación con el contexto cultural18, así como el peso de otras influencias marco, tal como la relacionadas al juego digital y la participación materna19. Los dispositivos móviles (DM) como los teléfonos inteligentes y las tabletas se han vuelto una parte integral en nuestro día a día. La adopción de estos dispositivos en nuestro país muestra que el 92% de los hogares con niños entre los 9 y 17 años cuenta con télefono inteligente y el 50% con una tableta1, aunque no contamos con datos que visualicen el uso por población preescolar. La experiencia internacional apunta que los niños acceden a tecnologías a menor edad y con mayor frecuencia que las generaciones anteriores2. Estos dispositivos son atractivos, fáciles de usar por niños preescolares3, sensibles al tacto4, portátiles5 y proveen una respuesta contingente e interactiva 6,7. Junto con la abundante oferta de contenidos y actividades disponibles a través de las aplicaciones (apps)6, explican parcialmente que los padres usen esta tecnología para que sus hijos aprendan y se entretengan. Si bien ha sido establecido que las conductas parentales y la cualidad de la interacción padres e hijos moldean de manera crítica el desarrollo infantil8,9, existe poca investigación que investigue como cambia el rol de los padres cuando interactúan con sus hijos durante el uso conjunto de DM5. 1. ¿Cuál es la frecuencia de JME-DM en Chile? 2. ¿Cuál es la relación entre los factores sociodemográficos, las creencias y la frecuencia de JME-DM? 3. ¿Difiere la interaccion madre-hijo/a en sesiones JME- DM dependiendo del contexto inducido por el investigador? Preguntas de Investigación Estudio Uno Encuestas Metodología Referencias Madres >18a con hij@ 4a Al menos un DM en casa N=359 Tamaño Criterio de exclusión Datos socio demográficos Cuestionario uso de TD y creencias relacionadas Patient Health Questionnaire (PHQ-9) Escala de involucramiento Temperamento niño (surgencia, CBQ-vsf) N=60 díadas N=30 díadas EG Educativo 10’ minutos video grabados JME-DM “usen el DM tal como típicamente lo harían en su hogar cuando quieres que tu hijo/a [juegue/ aprenda] con la tableta.” Fidelidad Interacciones madre e hijo: Contenido Positivo (andamiaje) y Negativo (intrusión) Afecto Positivo y Negativo Responsividad al niño Compromiso en la tarea Verbalizaciones Playfullness madre Interacciones hijo a madre: Afecto Positivo y Negativo Responsividad a la madre Compromiso en la tarea Verbalizaciones • Madres de mayor edad • Con mayor años de educación • Con más uso de DM • Más involucradas en la vida del niño • Creencias positivas relativas al uso de DM Frecuencia JME-DM (+) (+) (+) (-) • Madres que creen que su hijo es “nativo digital” Participación de las madres en JME-DM 1 Cabello, P., Claro, M., Lazcano, D., Cabello-Hutt, T., Antezana, L., & Ochoa, J. M. (2017). Implem


Context Questions Methods Step 1. We used modeling and simulation to predict the crop phenotypic plasticity resulting from the interaction of plant traits, climatic variability and management actions. e SUNFLO crop model [1,2] was parameterized for 35 recent oleic and linoleic sunﬂower cultivars. e values of the genotype-dependent parameters were obtained by measuring 10 phenotypic traits in dedicated ﬁeld platforms (2 locations per year) or controlled conditions [3,4]. Variety assessment is a key component of crop performance improvement (e.g. potential yield, quality, disease resistance, abiotic stress tolerance, environmental beneﬁts) and this process is still largely based on experimental approaches in ﬁeld. Plant phenotyping and crop modeling open the possibility to predict crop performance in agricultural conditions that are not tested in the variety assessment chain, yet which can occur in the target population of environments. Our objective is to present an integrated framework for variety assessment based on crop modeling in order to widen and complete the current informations on varieties provided by national advisory services or extension services for a large range of environmental and agronomic conditions. e potential use of this framework will be illustrated on sunﬂower crop as a proof of concept. Results Figure 1. Design of the MET used for model evaluation. First, we phenotyped newly released hybrids varieties in independent trials in ﬁeld and controlled conditions to set up the genotype-dependant parameterization of the crop model. en, we evaluated SUNFLO prediction capacity on the MET (relative RMSE for oil yield: 15.8%) and its capacity to rank those commercial hybrids (Kendall’s tau = 0.39, p < 0.01) for oil yield. We also tested the model capacity to simulate GxE interactions in the numerical experiment (step 3) by comparing two nested linear mixed models diﬀering by the interaction term (LRT: χ2(482) = 3561, p < 0.001, interaction model was a better ﬁt). Additionally, we showed that the SUNFLO crop model could provides indicators of the crop exposition to abiotic stress, which could be used to explain yield variance (Figure 3). ‣ How to leverage crop modeling to improve the assessment and recommendations for new varieties ? ‣ Can we recommend varieties to reduce phenotype-environment mismatch in the targeted cropping area ? Figure 2. A four step approach to include crop modeling in the variety recommendation process. e representation of the variety assessment chain (upper part in the diagram) is based on the current French system, with two years on trials before variety release (variety evaluation MET), and two year aer (agricultural extension MET). e presented approach leverage existing trials to get informations on tested varieties and to evaluate the crop model (steps 1-2). Aer designing numerical experiments, simulation would then provides recommendation for variety choice, accounting for growing conditions and climatic uncertainty (steps 3-4). e simulation of phenotypic plasticity makes possible a set of applications in variety assessment for breeders and advisers [5]: ‣ e characterization of abiotic stress as perceived by plants in each trial environment, providing that few control genotypes are included. ‣ e benchmarking of performance for material registered in diﬀerent years, i.e. having experienced distinct climatic conditions. ‣ e determination of agronomic suitability of released varieties, and especially their suitability to drought-prone areas and the optimal management for each variety type. Conclusions and perspectives References and contact 1. Casadebaig P, Guilioni L, Lecoeur J, Christophe A, Champolivier L, Debaeke P. SUNFLO, a model to simulate genotype-speciﬁc performance of the sunﬂower crop in contrasting environments. Agricultural and Forest Meteorology. Elsevier; 2011;151: 163–178. doi:10.1016/j.agrformet.2010.09.012 2. Lecoeur J, Poiré-Lassus R, Christophe A, Pallas B,


Faculty of Polymer Techology • Ozare 19, SI-2380 Slovenj Gradec • M: +386 31 339 985 • W: www.ftpo.eu Understanding the bonding strength of hybrid-produced thermoplastic composites to enable homogenous recycling T. Stiller a, J. Slapnik b, B. Zink c, C. Wick d, J. Vidal e, R.C. Kerschbaumer a a Polymer Competence Center Leoben GmbH, Leoben, Austria | roman.kerschbaumer@pccl.at INTRODUCTION Nowadays the development of technologies leads to more possibilities regarding applications and properties. Especially the progress of existing technologies enables the production of high-performance composite structures with recyclable thermoplastic matrices. By combining different processing technologies, a hybrid-produced part joins their advantages. Nevertheless, by combining materials and technologies the path at end of life usually ends in thermal recycling. Without doubt this is a waste of resources, since thermoplastic components can be easily recycled if separated correctly. RESULTS REFERENCES 1 A. Szuchács et al. (2022) Bonding strength calculation in multicomponent plastic processing technologies, Mater. Manuf., 37:2, 151-159, DOI: 10.1080/10426914.2021.1948052 2 Gašper Tič, Influence of processing parameters and surface roughness on the adhesion between overprinted thermoplastic polyurethane components and injection molded polyamide plates, Master thesis (2023) IPPT_TWINN | July 2023 www.ippt-twinn.eu IPPT_TWINN - Reinforcing the scientific excellence and innovation capacity in polymer processing technologies of the Faculty of Polymer Technology ACKNOWLEDGEMENT: This research was funded by the Horizon Europe Framework Program and the call HORIZON-WIDERA-2021-ACCESS-03, under the grant agreement for project 101079051 – IPPT_TWINN. b Faculty of Polymer Technology, Slovenj Gradec, Slovenia c Budapest University of Technology and Economics, Budapest, Hungary d Eastern Switzerland University of Applied Sciences, Rapperswil, Switzerland e AITIIP Technology Center, Zaragoza, Spain METHODOLOGY Within the IPPT_TWINN project it is the goal to manufacture thermoplastic composites via hybrid technologies as thermoplastic resin transfer molding (T-RTM) [1], injection molding (IM), and additive manufacturing (AM). Not only technologies are combined, but also materials such as polyamide and thermoplastic elastomers, to adapt properties locally, e.g., the bonding strength. Especially AM enables the individualization of parts. Therefore, AM will be applied to print structures or geometries on test specimens manufactured via the T-RTM and IM technology . To study the correlations between printing parameters and bonding strength, a mathematical model is developed [2]. Finally, the bonding strength is tested by fracture mechanical approaches. These tests provide information of the maximum bonding strength and, hence, the required energy to separate the materials from each other. By this, the separated materials can be recycled in a homogenous material stream to raw material and, thus, reused. Manufacturing Testing (A) Production of parts with hybrid technologies and different material combination (B) Investigation of dominant parameters for bonding strength with different testing methods (C) Successful separation of material combinations can be introduced to recycling cycle (A) (B) (C) 𝑴𝑝𝑟𝑜𝑐𝑒𝑠𝑠, 𝑚𝑎𝑡𝑒𝑟𝑖𝑎𝑙, 𝑐𝑜𝑚𝑏𝑖𝑛𝑎𝑡𝑖𝑜𝑛+ 𝑻𝐴(𝑣, 𝑇, 𝑝, … ), 𝐵𝑣, 𝑡, 𝐹, 𝑇, . . . , 𝐶 = 𝑄(ℎ𝑦𝑏𝑟𝑖𝑑𝑝𝑎𝑟𝑡) CONCLUSION The correlation between bonding strength and the single parameters, follows a polynomial function, with an optimum in bonding strength for a special parameter setting. This correlation defines the hybrid part quality. By combining different settings optimums at a similar level can be achieved. Further tests are planned to include more processing parameters. Considering this information, composite parts can be optimized in the bonding but furthermore separated to ensure a homogenous recycling stream which is necessary to keep the quality of recycled material. Thermoplast


In July 2013, the Becker Medical Library at Washington University in St. Louis held a workshop for librarians on the Becker Model, a framework developed by research assessment librarians for quantifying medical researchers' individual and group outputs. Following the workshop, the Becker Model was analyzed for content to adapt it to the physical sciences. This poster presents the process and results of applying their model to the curriculum vitae of a Yale University astronomy professor. ABSTRACT • Examine commonalities and differences between medical and physical sciences fields regarding research impact. • Review literature on scholarly assessment in astronomy to determine the types of assessment that matter. • Apply the Becker Model to citation data and ancillary CV data of an astronomy faculty member at the institution as a proof-of-concept for adapting the Model. • Create a program for research impact workshops to address a diverse physical, life, and social sciences clientele. OBJECTIVES Borne, K. (2001). Data mining in astronomical databases. Mining the Sky, 671–673. doi: 10.1007/10849171_88 Bornmann, L., & Daniel, H. (2009). The state of h index research: Is the h index an ideal way to measure research performance? EMBO Reports, 10(1). doi:10.1038/embor.2008.233 Fortson, L., Masters, K., Nichol, R., Edmondson, E. M., Lintott, C., Raddick, J., Schawinski, K., & Wallin, J. (2012). Galaxy Zoo. In M. J. Way, J. D. Scargle, K. M. Ali, & A. N. Srivastava (Eds.), Advances in Machine Learning and Data Mining for Astronomy (pp. 213–236). Boca Raton, FL: CRC Press. doi:10.1201/b11822-16 Garfield, E. (1979). Is citation analysis a legitimate evaluation tool? Scientometrics, 1(4), 359–375. doi:10.1007/BF02019306 Ginsparg, P. (2011). ArXiv at 20. Nature, 476(7359), 145–7. doi10.1038/476145a Harley, D., Acord, S. K., Earl-Novell, S., Lawrence, S., & King, C. J. (2010). Assessing the future landscape of scholarly communication: An exploration of faculty values and needs in seven disciplines. Berkeley, CA. Retrieved from https://escholarship.org/uc/item/15x7385g.pdf Havemann, F., & Larsen, B. (2014). Bibliometric Indicators of Young Authors in Astrophysics: Can Later Stars be Predicted? arXiv Preprint, 1–14. arXiv:1404.3084 Hourclé, J. A. (2012). Advancing the practice of data citation : A to-do list. Bulletin of the American Society for Information Science and Technology, 38(5), 20–22. Retrieved from http://www.asis.org/Bulletin/Jun-12/ JunJul12_Hourcle.pdf Jamali, H. R., & Nicholas, D. (2009). E-print depositing behavior of physicists and astronomers: An intradisciplinary study. The Journal of Academic Librarianship, 35(2), 117–125. doi:10.1016/j.acalib.2009.01.005 Kousha, K., Thelwall, M., & Rezaie, S. (2010). Can the impact of scholarly images be assessed online? An exploratory study using image identification technology. Journal of the American Society for Information Science and Technology, 61(9), 1734–1744. doi:10.1002/asi.21370 Larivière, V., Sugimoto, C. R., Macaluso, B., Milojević, S., Cronin, B., & Thelwall, M. (2014). arXiv E-prints and the journal of record: An analysis of roles and relationships. Journal of the Association for Information Science and Technology, 65(6), 1157–1169. doi:10.1002/asi.23044 Lawrence, B., Jones, C., Matthews, B., Pepler, S., & Callaghan, S. (2011). Citation and peer review of data: moving towards formal data publication. The International Journal of Digital Curation, 6(2), 4–37. Lozano, G., Larivière, V., & Gingras, Y. (2012). The weakening relationship between the Impact Factor and papers’ citations in the digital age. arXiv Preprint, 2140–2145. doi:10.1002/asi Penfield, T., Baker, M. J., Scoble, R., & Wykes, M. C. (2013). Assessment, evaluations, and definitions of research impact: A review. Research Evaluation, 23(October 2013), 21–32. doi:10.1093/reseval/rvt021 Pepe, A., & Kurtz, M. J. (2012). A measure of total research impact independent of time and discipline. PloS One, 7(11), e46428. do


METHODS Three different protocols were tested: ▪Horse constitutes an important veterinary patient and a relevant animal model owed to their physiopathological analogies with human. ▪MSCs are promising therapy for several diseases, including musculoskeletal disorders. ▪However, MSCs present several drawbacks → senescence in culture and require repeated tissue harvesting: more heterogeneity and invasive procedures. ▪To increase MSC availability and reduce invasive procedures, it is possible to derive MSCs from iPSCs → iMSCs. ▪While human iMSCs are being intensively studied, only two equine studies have reported the generation of eiMSCs to date (Lepage et al., 2016 and Chung et al., 2019). INTRODUCTION Derivation of equine induced Mesenchymal Stem Cells (eiMSCs) from equine induced Pluripotent Stem Cells (eiPSCs): a promising step for veterinary and translational regenerative medicine María Belén Serrano1, Elvira Bernad1, Alina Cequier1,2, Francisco José Vázquez1,2, Antonio Romero1,2, Arantza Vitoria1,2, Pilar Zaragoza1, Clementina Rodellar1, Laura Barrachina1,2 (1) Laboratorio de Genética Bioquímica LAGENBIO – Instituto Agroalimentario de Aragón – IA2 (Universidad de Zaragoza – CITA) – Instituto de Investigación Sanitaria de Aragón (IIS), Zaragoza, Spain (2) Servicio de Cirugía y Medicina Equina, Hospital Veterinario, Universidad de Zaragoza, Zaragoza, Spain Contact: lbarrach@unizar.es RESULTS ➢Deriving eiMSCs from eiPSCs is feasible and these could be established as an interesting alternative to eMSCs. ➢We have detected some differences in eiMSCs among lines and compared to eMSCs, such as immunophenotype and their differentiation potential, mainly for chondrogenesis. However, variability of eMSCs has also been noted among tissue sources and between individuals. ➢Further studies are needed to analyse eiMSCs properties and immune function to improve cell therapies under One Medicine perspective. CONCLUSIONS Cell culture Spontaneous differentiation Directed differentiation ABBREVIATIONS: DMEM LG = Dulbecco`s Modified Eagle`s Medium Low Glucose; FBS = Fetal Bovine Serum; L-glut = L-glutamine; S = Streptomycin; P = Penicillin; VTN = Vitronectin; SB431542 = TGF-β receptor kinase inhibitor; bFGF = basic Fibroblast Growth Factor; eiNCCs = equine induced Neuro Crestal Cells; CDM = Chemically Defined Medium; CHIR99021 = GSK-3α/β inhibitor; AF = Attachment Factor; MEFs = Mouse Embryonic Fibroblasts; EGF = Epidermal Growth Factor. To obtain eiMSCs and compare their main characterization criteria over primary equine MSCs (eMSCs). OBJECTIVE PROTOCOL 3. Differentiation via neural crest pathway →3 stages PROTOCOL 1. Switch to MSC media Chung et al., 2019 PROTOCOL 2. Switch to specific differentiation media Lepage et al., 2016 Immunophenotype (flow cytometry) Trilineage differentiation Gene expression (qPCR) PID2020-116352GB-I00 The first 2 passages →VTN; next passages →tissue-treated culture plate DMEM LG 10% FBS 2mM L-glut 0.1 mg/mL S 100 U/mL P 10 µM SB431542 5 ng/mL bFGF The first 2 passages →VTN; next passages →tissue-treated culture plate The first 10 days of culture DMEM LG 10% FBS 2mM L-glut 0.1 mg/mL S 100 U/mL P 20 ng/mL bFGF The first 2 passages →VTN; next passages →tissue-treated culture plate CDM 10 µM SB431542 1 µM CHIR99021 VTN; 4 passages AF + MEFs; 10 days CDM 10 µM SB431542 20 ng/mL bFGF 20 ng/mL EGF 1. eiNCCs induction 2. eiNCCs expansion 3. eiMSCs induction Ctrl C A O Ctrl = control culture A = Adipogenic differentiation C = Chondrogenic differentiation O = Osteogenic differentiation Ctrl C A O eiMSCs line 1 eiMSCs line 3 eiMSCs line 2 Ctrl C A O Reference sample →each eiPSCs line PROTOCOL 1 eiPSCs eiPSCs PROTOCOL 2 1. eiNCCs induction 2. eiNCCs expansion 3. eiMSCs induction PROTOCOL 3 eiPSCs line 1 eiPSCs line 2 eiPSCs line 3 eiMSCs line 1 eiMSCs line 2 eiMSCs line 3 Fukuta et al., 2014; Chijimatsu et al., 2017; Nakamura et al., 2021; Kamiya et al., 2022 Bone marrow eMSCs DMEM LG 10% FBS 2mM L-glut 0.1 mg/mL S 100 U/mL P C


Our Advisory Board, collaborators and adopters include: BioSharing is a web-based, searchable portal of 3 interlinked registries, containing both in-house and crowd-sourced curated descrip?ons of standards, databases and data policies. Indicators of readiness and use highlight mature standards and databases endorsed by data policies from journals and funders. It’s so simple and quick to register your resource. Go to biosharing.org/new to get started.


NOAA STAR SOCD OceanView: The Level-4 thermal fronts module Prasanjit Dash1,2, Marouan Bouali3, Jorge Vazquez4, Paul DiGiacomo1 1NOAA STAR SOCD, College Park, MD, USA; 2CSU CIRA, Fort Collins, CO, USA; 3IOUSP, São Paulo, Brazil; 4JPL/Caltech, Pasadena, CA, USA Preamble: The NOAA STAR SOCD OceanView (OV) v1.0 was publicly released in May-2021 at https://www.star.nesdis.noaa.gov/socd/ov/. The OceanView is a web-based application delivering an integrated display of remote sensing, in situ, and model data over oceans, polar areas, and coastal and inland waterways [1]. It incorporates products primarily from NOAA and some from NASA and other sources. The application comprises several modules, including an experimental thermal fronts component capable of deriving and interactively visualizing level-4 SST fronts. This L4 fronts module will potentially contribute to the GHRSST Climatology and L4 Inter-comparison Task Team (IC-TT) in discussion with its participants and other enthusiasts. Here, we demonstrate the existing capability with only one L4 SST and aim to gauge features of interest and potential extension to meet GHRSST TT objectives. S3. Calibration, validation and product assessment Abstract ID 42; virtual The Satellite Oceanography and Climate Division (SOCD) of NOAA STAR released the OceanView v1.0 in 2021. The L4 fronts module of OceanView currently has only one L4 SST front (NOAA GOES-POES blended). However, the system is scalable and will be expanded depending on identified needs and the path forward. This preliminary illustration aims to gauge features of interest and potential extension to meet GHRSST IC-TT objectives. The work is experimental and will likely undergo improvements in both algorithm and validation approaches. References [1] Dash, P. and DiGiacomo, P, 2021: The NOAA STAR SOCD OceanView (OV): an application for integrated visualization of satellite, in situ, and model data & ocean events – the debut release.; GHRSST XXII Proc. Virtual meeting, 7-11 June 2021. https://doi.org/10.5281/zenodo.5750123 [2] Maturi, E., and Coauthors, 2017: A New High-Resolution Sea Surface Temperature Blended Analysis. BAMS, 77–80, 21–30, https://doi.org/10.1175/BAMS-D-15-00002.1 [3] Martin, M., and Coauthors, 2012: Group for High Resolution Sea Surface temperature (GHRSST) analysis fields inter-comparisons. Part 1: A GHRSST multi-product ensemble (GMPE). DSR. II, 77–80, 21–30, https://doi.org/10.1016/j.dsr2.2012.04.013 [4] Dash, P., and Coauthors, 2012: Group for High Resolution Sea Surface Temperature (GHRSST) analysis fields inter-comparisons. Part 2: Near real time web-based level 4 SST Quality Monitor. DSR. II, 77–80, 31–43, https://doi.org/10.1016/j.dsr2.2012.04.002 Acknowledgment JPSS program, Ocean Remote Sensing (funding); GHRSST IC-TT members for discussions. 23rd International Science Team Meeting (GHRSST XXIII), Barcelona 27 June – 1 July 2022 and virtual; contact: prasanjit.dash@noaa.gov (https://orcid.org/0000-0002-8789-0506) Simplified overview of: Science Technology Example Summary Experimental L4 front module • interactive profiler for individual fronts • filters for avg length, gradient & avg. SST 1. Calculate gradient values per pixel using finite difference, with central differences in the interior and first differences at the boundaries. 2. Use Sobel operator to detect edges. Canny was also tested (Marouan B.) but did not seem to provide significant improvement. Numerical operations 3. Adaptive threshold for Sobel filter using cumulative distribution function 4. Binarize to 1 or 0 using the above threshold 5. Skeletonize to make it thinner (1-pixel) 6. Contourize the detected edges (computer vision) Morphological operations 7. Store gradient values & location info for each point on the contours (for web interactivity) 8. Store average SST and length for each contour as attributes (for web interactivity) 9. Save all features in a GeoJSON file for web-display *These steps enable web-visualization & provide in


Одним из аспектов исследования режимов использования участков ЛПХ является оценка степени распаханности, базирующаяся на детектировании наличия и площади пашни, показывающая долю культивируемой пашни от общей площади участка. На участках ЛПХ выделены полигоны трёх классов: пашня, здания и сооружения, прочие объекты. По данным спутниковых снимков Sentinel-2 вычислены временные ряды индексов GNDVI, MCARI, MSI и NDMI, и их статистики за вегетационный период. Были обучены 4 модели машинного обучения – градиентный бустинг, деревья решений, случайный лес и метод опорных векторов. Классификация выполнена на уровне пикселей. Выбор классификационной модели на основе оценок точности по тестовой выборке. Итоговая предиктивная классификация всех участков территории выполнена методом градиентного бустинга который показал точность классификации выше остальных рассматривавшихся методов. Номер класса Метрики точности Градиентный бустинг (Gradient Boosting) Случайный лес (Random Forest) Дерево решений (Decision Tree) Метод опорных векторов (Support Vector Machines) Overall Accuracy 0.973 / 0.877 0.986 / 0.870 0.891 / 0.856 0.924 / 0.853 1 Producer’s Accuracy 0.984 / 0.984 0.959 / 0.973 0.928 / 0.963 0.981 / 0.992 User’s Accuracy 0.977 / 0.857 0.987 / 0.856 0.924 / 0.848 0.981 / 0.825 2 Producer’s Accuracy 0.954 / 0.656 0.976 / 0.664 0.864 / 0.634 0.840 / 0.584 User’s Accuracy 0.956 / 0.945 0.988 / 0.919 0.846 / 0.892 0.948 / 0.967 3 Producer’s Accuracy 0.934 / 0.712 0.935 / 0.680 0.584 / 0.696 0.677 / 0.560 User’s Accuracy 0.968 / 0.918 0.975 / 0.904 0.694 / 0.837 0.916 / 0.946 Распаханность 0.0 – 0.1 0.1 – 0.2 0.2 – 0.3 0.3 – 0.4 0.4 – 0.5 0.5 – 0.6 0.6 – 0.7 0.7 – 0.8 0.8 – 0.9 0.9 – 1.0 0.00 0-0.1 0.1-0.2 0.2-0.3 0.3-0.4 0.4-0.5 0.5-0.6 0.6-0.7 0.7-0.8 0.8-0.9 0.9-1 0.05 Доля участков Распаханность 0.10 0.15 Класс 1 – пашня (524 объекта) Класс 2 – иные земли (116 объектов) Класс 3 – здания и сооружения (177 объектов) а) Градиентный бустинг (Gradient Boosting) б) Дерево решений (Decision Tree) в) Случайный лес (Random Forest) г) Метод опорных векторов (Support Vector Machines) Распахиваемые земли Здания и сооружения Иные земли Степень распаханности: N – общее количество пикселей участка N1 – количество пикселей класса 1 (распахиваемые земли) R= N 1 N Оценка степени распаханности участка выполнена на основе попиксельной классификации как отношение количества пикселов, классифицированных как класс «пашня» к общему количеству пикселов участка, попадающего в полигон, выраженной в процентах. Результаты классификации были картированы с использованием цветовой шкалы степени распаханности от 0 до > 100%. На территории исследования по состоянию на 2022 год около 18% всех участков имеет распаханность менее 10%, низкий уровень распашки (от 0 до 20%) имеет около 30% участков, средний уровень (от 20 до 50%) – около 50% участков, около 20% участков имеет высокий уровень распашки (более 50%). Введение Методы Результат I Алгоритм обработки данных Выборка объектов Классификация Расчёт степени распаханности Оценка распаханности участков личных подсобных хозяйств с использованием методов машинного обучения по данным Sentinel-2 Артем Александрович Сабаев (artsab@yahoo.com), Елена Владимировна Понькина (ponkinaelena77@mail.ru) Алтайский государственный университет, Барнаул Территория — с. Кытманово, пос. Тягун, Кытманушка, Алтайский край Результат II Точность классификации, объекты тренинговой выборки/объекты тестовой выборки Разработанный инструментарий представляется перспективным для внедрения в систему мониторинга режимов использования участков ЛПХ на уровне сельских населенных пунктов, в частности детектирования пашни и забрасываемости участков. Анализ пространственных паттернов как и поиск факторов культивации пашни на участках ЛПХ в населенных пунктах представляет интерес для дальнейшего исследования. Заключение DOI: 10.5281/zenodo.14048405


AN INTERNATIONAL CENSUS OF RESEARCH SOFTWARE IN INSTITUTIONAL ACADEMIC REPOSITORIES. This work expands on previous research, which examined 182 academic IRs from 157 universities in the UK¹. Few records of research software were found in IRs and the majority of IRs could not contain software as independent records of research output due to the underlying Research Information System (RIS) platform. Expanding on this work, similar analyses were performed on international IRs in what we believe is the first such census of its kind. 4,970 repositories from 125 countries were examined for the presence of software, along with repository-based metadata for potentially correlating factors. This will add evidence to the movement to recognise software as distinct and recordable research output in its own right. KEY RESULTS INTRODUCTION References [1] Carlin D, Rainer A, Wilson D. 2023. Where is all the research software? An analysis of software in UK academic repositories. PeerJ Comput. Sci. 9:e1546 http://doi.org/10.7717/peerj-cs.1546 [in press] [2] OpenDOAR. Online: https://v2.sherpa.ac.uk/opendoar/ CONCLUSIONS Dr. Domhnall Carlin | Centre for Secure Information Technologies, Queen’s University Belfast, N. Ireland. | d.carlin@qub.ac.uk No software search 50% Does not contain software 22.5% Error 19.9% Contains software 7.6% Analysis of repositories METHODOLOGY Source data were compiled from OpenDOAR², the directory of global Open Access Repositories. A list of institutional academic repositories was derived, providing URLs, country code and RIS platform. Each URL from 4,970 repositories across 125 countries was visited manually to search for research software. Each repository was categorised as one of: Contains software: software is a searchable item and the repository contains such records Does not contain software: software is a searchable item but the repository contains no such records No software search: software is not recognised as a specific item of output Europe 1856 America 1439 Asia 1364 Africa 214 Repositories per continent 0 500 1,000 1,500 2,000 2,500 dspace eprints weko digital commons Unknown islandora opus contentdm hal pure Top 10 RIS platforms Only 7.6% of IRs sampled globally contained software Around 30% could contain software Half did not recognise software as a discrete type of output Dspace accounts for nearly 40% of repositories Default config includes software as a type¹ However, 64.4% had no search item for software Defaults may have been removed A single word in a config file can allow software types (e.g. EPrints) Many IRs adopt Dublin Core Metadata format, but do not use defined vocab for types 1. Software is scarcely indexed in IRs 2. RIS platforms appear to have defaults altered 3. This may often be a policy issue, not a technical one FUTURE WORK Create a dedicated dashboard to monitor the change over time of software in IRs Automate the detection of software artefacts through lightweight and ethical harvesting Increase the coverage of the source data, particularly in underrepresented regions and countries Systematically clean the data using source code from repositories to provide metadata Use this evidence to inform policy lobbying initiatives Acknowledgements This work was supported as part of Dr Carlin’s UKRI EPSRC Research Software Engineering Fellowship (EP/V052284/1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


88 09-10 | 05 | 2019 Αθήνα | Ελλάδα 2019 ΕΛΕΒΙΤ - Ελληνική Εταιρεία Βιοϊατρικής Τεχνολογίας 2019 ELEVIT- Hellenic Society for Biomedical Technology c c PRELIMINARY RESULTS ON COMPUTERIZED ANALYSIS OF BOWEL SOUNDS CAPTURED FROM A NOVEL WEARABLE DEVICE V. Charisis*, S. Hadjidimitriou*, D. Iakovakis*, H. Placido da Silva**, S. Bostantzopoulou***, Z. Katsarou****, and L. Hadjileontiadis***** *Department of Electrical and Computer Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece, **PLUX Wireless Biosignals, Lisbon, Portugal, ***Third Neurological Clinic, G. Papanikolaou Hospital, Thessaloniki, Greece, ****Department of Neurology, Hippokration Hospital, Thessaloniki, Greece, *****Department of Electrical and Computer Engineering, Khalifa University of Science and Technology, Abu Dhabi, UAE vcharisis@ee.auth.gr, stellios22@gmail.com, dimiiako12@gmail.com, hsilva@plux.info, bostkamb@otenet.gr, katsarouzoe@gmail.com, leontios.h@kustar.ac.ae Abstract Bowel sounds (BS), the noises produced by the movement of ﬂuids and gas during the peristaltic movement of intestines, are useful in clinical practice as their auscultation constitutes a traditional technique for identifying gastrointestinal (GI) health status. Assessing patients with GI disturbances presents many challenges for a health professional. In this direction, there are research eﬀorts that focus on computerized BS analysis systems in order to detect GI motility problems. The aim of this work is to present an alternative technique to process BS, captured by a novel comfortable wearable device, namely smart belt, that captures 3-channel BS recordings at up to 3KHz sampling frequency, during a soda tolerance test (STT). The processing pipeline is applied separately on each sound channel and consists of two steps. At Step 1, the BS recordings are adaptively denoised via a wavelet transform-based stationary non-stationary ﬁlter (WTST-NST) [1] that separates sound events of interest (SEOI) from background noise. By applying the WTST-NST ﬁlter, the coherent structure of bowel sounds or other similar sound events (non-stationary) is revealed and separated from the superimposed interfering background noise (stationary). The output of Step 1 is subjected to time-frequency analysis based on the Continuous Wavelet Transform using the Morlet wavelet. The target is to identify the frequency content of each candidate bowel sound event and characterize it as bowel sound or artefact [2]. In this context, the output of this process is a bowel sound mask signal per channel with non-zero values that correspond to the positions of bowel sound events. Finally, three GI mobility indices are calculated, i.e., BS per minute (BSPM), sound-to-sound interval (SSI) and mean BS duration (BSD). The above analysis pipeline was evaluated on a dataset consisting of BS recordings from 7 adult subjects during an STT, along with expert-based BS annotations as the ground truth. The performance is evaluated via the measures of the true positive rate (TPR) and sensitivity. In overall, the TPR is 40-80%, implying that in many cases there are a lot of false positive events, whereas the highest TPR of each subject, produced by a single channel, ranges between 60-80%. The relatively high number of false positives may be caused by the way the expert evaluated the abdominal sound recordings, i.e., by listening to a single three-channel audio ﬁle rather than three separate single audio ﬁles. In this way, the expert may have missed or misinterpreted bowel sounds that appear on a single channel and are suppressed by the superposition of the other two. Sensitivity, in overall, ranges from 50% to 98% while the best performance by a single channel for each subject is higher than 70% in most cases. The results of the motility indices calculation validate the expected behaviour, i.e., BSPM increase and SSI decrease during the SST. However, this was not the case for BSD that slightly decreased instead of the op


Implications of the mid-IR for ALMA flare observations Hugh Hudson1,2, Sam Krucker2,3, Matt Penn4, and Paulo Simões1 1U. of Glasgow, UK; 2UC Berkeley, USA; 3FHNWS, Windisch, Switzerland; 4NSO Tucson, AZ USA Synopsis: Mid-IR observations (the 10µ band) of solar flares have now become possible (Kaufmann et al. 2015; Trottet et al. 2015; Penn et al. 2016). This poster reviews the new data in the ALMA context. Right: Schematic global spectra of a solar flare as it appeared to Ohki & Hudson (1975), for the impulsive phase (;eft) and the gradual phase (right) of a solar flare. The new IR observations: Several flares have now been observed in the 10µ band (Kaufmann et al. 2015). The most detailed results come from observations at the McMath-Pierce telescope of SOL2014-09-24 (Penn et al. 2016). Figures 1-4 (map, timeseries, overlays, spectrum) show these observations, made with independent QWIP array detectors in broad passbands at 5.2 µm and 8.2 µm. Above: There really is a gap in our observational parameter space, being fiilled in now via ground-based IR observations from above, and ALMA from below. pre-flare (5 μm) pre-flare (8 μm) flare peak (5 μm) flare peak (8 μm) 10 100 1000 frequency [THz] 102 103 104 105 differential radiative energy flux [sfu] 100 x hot coronal free-free pre-flare black body from IR source 10 1 wavelength [micron] 8.6 micron: 24-Sep-2014 17:49:24.483 -385 -380 -375 -370 -365 -360 -355 X (arcsecs) -330 -325 -320 -315 -310 -305 Y (arcsecs) 20-100 keV 8.6 micron HMI 617 nm: 24-Sep-2014 17:49:18.900 -385 -380 -375 -370 -365 -360 -355 X (arcsecs) -330 -325 -320 -315 -310 -305 Y (arcsecs) 20-100 keV 617 nm AIA 94 A: 24-Sep-2014 17:49:13.120 -385 -380 -375 -370 -365 -360 -355 X (arcsecs) -330 -325 -320 -315 -310 -305 Y (arcsecs) 20-100 keV 94 A Fig. 1: Peflare (upper) and flare (lower) images in the two mid-IR passbands. Note the well-resolved sunspots and faculae, and the excellent signal-to-noise ratio for the flare emissions. The flare footpoint sources are not resolved spatially. Fig. 2: Light curves of the two mid- IR bands and hard X-rays observed by RHESSI. The background gray figure shows GOES 1-8Å. The IR time variability is not well resolved at 1 s. Fig. 3: Images at 8.2µ, HMI white light, and AIA 94Å, overlaid with RHESSI hard X-ray contours. Fig. 4: Spectrum at the peak of the flare, combining the two mid-IR points with the HMI observation in “white light.” The infrared spectrum matches that expected from optically-thin thermal bremsstrahlung. Significance: The excellent signal-to-noise ratio in the observations of SOL2014-09-24 leads to great optimism about future observations, since it was a minor event (GOES class C7.4). We were surprised to see the clear identification of the mid-IR sources with the impulsive-phase signatures in the deep atmosphere. These data therefore will contribute enormously to our knowledge of the main flare energy release. Other new IR observations: The observations described above add to the remarkable progress of the group of Pierre Kaufmann (São Paulo) in several directions, including the observation of several other flares at 30 THz (the 10µ band). They have also successfully observed solar flares in the “sub- THz” range at 212 GHz and 405 GHz. These systematic observations come from a dedicated facility at the El Leoncito site in the Andes. Most recently, this group has recently completed a successful balloon flight pioneering solar observations in the far IR at 3 THz and 7 THz. All of this contributes to filling in the great spectral gap that has heretofore existed. Implications for ALMA: Between the new mid- and far-IR observations now appearing, and the forthcoming ALMA flare observations, we will be able to characterize the flaring atmosphere directly, using the easy-to-characterize continuum rather than having to rely on the complexities of radiative transfer in spectral lines. The figure below (Wedemeyer et al. 2016) shows quiet-Sun contribution functions for the A


MetaSearch: Phenotypic Search across public MRI data Satrajit Ghosh1, B. Nolan Nichols2, Katja Heuer3, Amy Robinson Sterling4, Roberto Toro5 1Massachusetts Institute of Technology, Cambridge, MA, 2Genentech, Menlo Park, CA, 3Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 4Princeton University, Princeton, NJ, 5Institut Pasteur, Paris, France Acknowledgements We acknowledge all who have made data available publicly and the support of Phase I funds for the Open Science Prize challenge. References [1] http://openneu.ro/ [2] https://github.com/OpenNeuroLab/metasearch [3] https://zenodo.org/ [4] https://osf.io/ Introduction Growing number of human brain imaging datasets shared online that have related metadata, such as disease diagnostics, age, sex and other phenotypic, demographic or imaging information. The 1000 Functional Connectomes Project (FCP) and International Neuroimaging Data-sharing Initiative (INDI) are great examples of openly available brain imaging datasets with corresponding metadata. However, these data have diverse directory structures and file formats that make cross-dataset queries a time intensive project. With MetaSearch, we propose a Web platform that allows finding resources, filtering information by a user's needs, and enables social, distributed curation of scientific data. It is provided by the Open Neuroimaging Laboratory as a companion to BrainBox, a brain MRI curation and annotation tool. Methods MetaSearch provides an integrated view of projects organized under the FCP efforts, but also data from Open Science Framework, Zenodo, Dropbox and others. It accomplishes this by extracting metadata for these projects from the AWS cloud, transforming it into a common data model, and then loading the integrated dataset into the MetaSearch app. MetaSearch uses an implementation of parallel coordinate charts written in D3.js that allows for selecting subsets of multidimensional datasets that are also rendered in a tabular format using SlickGrid. By using this app you can perform queries visually to select a cohort of participants with brain imaging data based on their demographics and phenotypic information and then link out to imaging measures. Using GitHub, we provide a common platform for other developers to contribute additional datasets to the search engine. Faceted search Brainbox Integration Map your data


Introduction Method Results Results Discussion Future Prospects Abstract Stuart Hall's communication model shows that media and other cultural contexts are molded by dominant discourses and power systems. Hence, this study uses Hall's model to analyze viral and harmful media stereotypes, their toxic effects on individuals and society, and media's role in shaping cultural perceptions. This study examines three levels of stereotypes— masculine power, gender stereotypes and social stigmas. Evidence synthesis is employed to evaluate several studies on damaging media stereotypes that match with Hall's postulations to extract and frame these biases for critical discourses. This study adds to the body of research on media representations by revealing how media stereotypes impair historical, cultural, and sexual identities. In the field of media and cultural studies, Stuart Hall’s (1973) communication model provides a useful framework for analyzing the interplay between discourse, power structures, and media. *Figure 2. Circle size is related to the number of studies mentioning the word. Circle color is related to the stereotype category. The lines connecting the nodes indicate semantic relationships or associations. The network reveals clusters of related terms. The semantic variability of this text network analysis is focused because it centers around specific themes and interconnected terms Text Network Analysis showing nodes extracted from titles, abstracts and/or Intros of the 61 studies Semantic Variability Scale of Nodes *Figure 5 . The United States made a complete contribution to all the selected research, accounting for 100% (61). These studies were sourced from 18 different states within the country. The research institutions in the Northeast region of the country accounted for 56% of the selected studies. New York State provided 33% of the entire papers, closely followed by California State in the Southwest, which accounted for 20%. Spatial Analysis showing the %-distribution of the selected studies (n = 61) within the US L - R The current analysis incorporates a range of trends shown in reviewed studies. The first chart shows 63% of respondents saying that the different forms of stereotypes are either perpetuated or reinforced by the media. The second chart shows 57% of respondents admit that the media perpetuates and reinforces human- related stereotypes by selectively covering specific pieces of information rather than the entirety. According to the third chart, most respondents (58%) believe that television is the primary medium through which media-driven stereotypes are spread (for example, in the form of films or broadcasts from news outlets.) Media in all its forms has long shaped society's values, norms, and beliefs (Tankard & Paluck, 2016). The fact that media signals are encoded with unique meanings by content providers is an endorsement of Hall's communication model. According to Hall (2000), these interpretations are impacted by many social, cultural, and political factors. Castleberry (2016) argues that ideological frameworks frequently impact the media's ability to encode messages that become stereotypes by giving more weight to some narratives and viewpoints and less weight to others. Take gender stereotypes as an example. Media portrayals frequently uphold damaging and restricting perceptions of masculinity and femininity by adhering to established gender norms and roles. Women are typically shown as nurturing figures or romantic interests, whereas males are typically portrayed as strong and dominating. These stereotypes normalize and legitimize uneven gender interactions, which in turn helps to perpetuate preexisting power systems. Bødker (2018) notes that audiences have a crucial role in understanding media messages and creating meaning by drawing on their personal experiences, beliefs, and cultural backgrounds, as emphasized by Hall's model. On the other hand, viewers may infer stereotypes from media por


ZeroPM - Policy The main objective of WP3-Policy is to stimulate and support policy changes to more effectively tackle persistent and mobile substances through regulatory measures. With this approach WP3 feeds into the “prevention”-objective of the toxic- free hierarchy. This will be achieved through the following sub-objectives: ▼To describe relevant European and international policy objectives and actions as well as needs and challenges for realising them. ▼To analyse opportunities and gaps in existing policy frameworks for preventing persistent and mobile substances from entering the environment. ▼To develop policy actions tailored to groups of persistent and mobile substances, uses or sectors and assess their impacts on different actors and sectors as well as their feasibility of facilitating a transition towards zero pollution from persistent and mobile substances (with WP4 Market transition) ▼To design roadmaps for groups of persistent and mobile substances, uses or sectors as well as to develop and disseminate concise policy messages by engaging with all relevant stakeholders throughout the project. Hans Peter Arp Deputy Coordinator hans.peter.arp@ngi.no Norwegian Geotechnical Institute & Norwegian University of Science and Technology Alicia McNeill Associate Advisor Alicia.McNeill@milieu.be Milieu Law & Policy Consulting Jona Schulze Associate Advisor Jona Schulze@uba.de German Environment Agency (UBA) Introduction ▼Analysis of the EU-level zero-pollution policy ambitions: actions, needs and challenges with respect to selected persistent and mobile substances ▼Suggested policy actions and roadmaps for meeting the zero-pollution ambitions ▼Policy briefs presenting key findings and recommendations for policy actions for meeting the zero-pollution ambitions Results ▼‘Regulatory watch’ to identify opportunities to feed findings into the EU regulatory process, e.g., upcoming reviews of the Urban Wastewater Treatment Directive, the Sewage Sludge Directive, and other relevant regulatory frameworks including REACH, CLP, and product legislation ▼Analysis of survey data and stakeholder feedback for new and recent legislative initiatives, including the Chemicals Strategy for Sustainability ▼Mapping of existing EU regulatory frameworks on chemicals including substances used in specific products as well as water, waste and soil policy ▼Development and assessment of policy options Example tasks Acknowledgements Mariya Gancheva, Melanie Muro, Tugce Tugran, Lucille Labayle, Milieu Law & Policy Consulting Alexander Badry, Tobias Mohr, UBA This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101036756. Sarah Hale Project Coordinator sarah.hale@ngi.no Norwegian Geotechnical Institute Partners Ivo Schliebner Advisor Ivo.Schliebner@uba.de German Environment Agency (UBA) Michael Neumann Advisor Michael.Neumann@uba.de German Environment Agency (UBA) Gretta Goldenman Advisor G.Goldenman@milieu.be Milieu Law & Policy Consulting Lise Oules WP3 leader Lise.Oules@mileu.be Milieu Law & Policy Consulting The first PMT/vPvM substances to be listed as SVHCs or to be proposed for restrictions under REACH zeropm.eu ▼Stakeholder interviews and workshops to explore the feasibility of policy measures ▼Synthesis and development of policy messages HFPO-DA (GenX) 1,4-dioxane PFHexA PFBS


The Effects of Ocean Acidification on the Metabolic Rate and Swimming Performance of Bonefish (Albula vulpes) Jake Valente, Makayla Barton, Kearney McDonnell, Sean McGurl, Olivia Millspaugh, Mickey Mittermeier, and Rennie Meyers Advisors: Aaron Shultz and Kit Hayward Methods Bonefish were collected with a seine net from Starved Creek in the spring of 2010, in Southern Eleuthera. They were transported back to the Cape Eleuthera Institute wet laboratory, where they were transferred to holding tanks. Bonefish remained in the holding tanks for a minimum of 48 hours before being transferred to their acclimation tanks. Tank pH was adjusted over a 24-hour period to predicted ocean acidification levels in 100 years made by the Intergovernmental Panel on Climate Change. The pH levels in the acclamation tanks were 7.8, 7.6, and 7.4. The bonefish were acclimated for a minimum of 7 days to the following pH treatment: 7.8, 7.6, and 7.4. Fish were not fed 48 hours prior to testing. The volume and weight of each fish was recorded before they were loaded into respirometry chambers, and this process is exemplified in figure 2. AutoResp4 software recorded oxygen consumption overnight during alternating recirculation and flush periods (Figure 3). During the recirculation period, water flows past a dissolved oxygen probe in a closed system. The six lowest oxygen consumption values collected during the recirculation period with r² >0.95 were averaged. Water from the surrounding tank is pumped through the chamber during the flush period in order to refresh the water. The following day, fish were transferred to a saltwater pool, with 3 parallel lines each 37 cm apart, and were exercised by pinching their caudal fins. The number of times a fish crossed a line and time until exhaustion was recorded. Fish were considered exhausted when they did not burst swim after 2 consecutive caudal pinches. Total and fork length of the bonefish was recorded, after which fish were recovered and released. Introduction Global Climate Change can be defined as any change in climate over time. Before the Industrial Revolution, CO2 concentrations were at a value of 280 parts per million (ppm), driving that level up to 385 ppm in 2008. Temperatures are rising at the fastest rate they ever have in the past 1,000 years. Coastal flats are classified as shallow marine environments including tidal creeks, lagoons and mangrove swamps. These environments are vital to the entire marine ecosystem because of their roles as nurseries for juvenile reef fish. Ocean acidity resulting from increased CO2 in the atmosphere may have negative impacts on fish. The average pH of the oceans has dropped by 0.1 and there has been a 30% increase in hydrogen ion concentration. When fish ventilate their gills, these ions diffuse through their gills and into their blood stream, creating and imbalance in their acid-base chemistry. This may increase the stress levels of fish, causing them to consume more oxygen, which in turn makes it difficult for the fish to carry out life processes. A species of fish that may be affected by these three factors is the bonefish. Bonefish also play a key role in local economies of the Bahamian Archipelago. Because of their strength and difficulty to catch, anglers travel to the Bahamas for recreational fishing. The purpose of this study was to test the effects of global climate change caused by anthropogenically produced CO2 on Bonefish. The test will measure both the oxygen consumption and the swimming performance of bonefish when they are exposed to incremental decreases in pH, which are the values predicted by the IPCC for the next 100 years. It was hypothesized that as pH decreased the swimming performance of Bonefish would decrease while their metabolic rate increased. Literature Cited Brierly, Andrew S and Kingsford, Micheal J. 2009. “Impacts of Climate Change on Marine Organisms and Ecosystems.” Current Biology. 19: 602-614. A.J. Danylchuk, S.E. Danylchuk, S.J.


Elevation Control on Vegetation Organization in a Semiarid Ecosystem in Central New Mexico Sai Siddhartha Nudurupati1, Erkan Istanbulluoglu1, Jordan M. Adams2, Daniel Hobley3, Nicole M. Gasparini2, Gregory E. Tucker3 and Eric W. H. Hutton4 1 Department of Civil and Environmental Engineering, University of Washington, Seattle, WA, USA 2 Department of Earth and Environmental Sciences, Tulane University, New Orleans, LA, USA 3 CIRES and Department of Geological Sciences, University of Colorado, Boulder, CO, USA 4 Community Surface Dynamics Modeling System (CSDMS), University of Colorado, CO, USA INTRODUCTION Semiarid and desert ecosystems are characterized by patchy and dynamic vegetation Topography has been observed to play a commanding role on vegetation patterns In this study, we investigate the role of elevation dependent climatology on vegetation organization in a semiarid catchment in New Mexico, USA We develop a ecohydrologic cellular automaton model within Landlab, a component based modeling framework for earth surface (http://landlab.readthedocs.org). The model couples local vegetation dynamics model with cellular automata plant establishment and mortality model based on Zhou et al. (2013). The model is driven by elevation dependent rainfall, temperature and radiation Model results reproduce elevation and aspect controls on observed vegetation patterns LANDLAB: ECOHYDROLOGY VEGETATION ORGANIZATION: ASPECT VEGETATION ORGANIZATION: ELEVATION MODELING ELEVATION DEPENDENCEKnow More About The Landlab here: http://Landlab.github.ioContact: saisiddu@uw.edu & erkani@u.washington.edu Landlab Ecohydrology Components: Storm Generator: generates rectangular Poisson distributed storms Radiation: calculates daily spatially distributed solar radiation (Radiation Factor) Potential Evapotranspiration (PET): uses solar radiation fields and weather variables to calculate PET at each model element Soil Moisture: solves root zone water balance between two storms given PET and rainfall fields ; returns actual evapotranspiration and soil moisture at inter storm durations Vegetation: computes net primary productivity based on actual evapotranspiration and calculates leaf area index and biomass Cellular Automata Competition: models competition by keeping track of probabilistically calculated mortality and establishment of plants driven by water stress and plant age Fig. 1: Point Model Validation of Leaf Area Index at Nebraska Sand Hills Fig. 2: Simulation on flat topography Fig. 3: Simulation on actual topography in Sevilleta, Central New Mexico Fig. 5: Observed elevation dependent land cover in a catchment in central New Mexico Fig. 4: Elevation dependence on Potential Evapotranspiration and Precipitation [1]References: 1. Caylor, Kelly K., Salvatore Manfreda, and Ignacio Rodriguez-Iturbe. "On the coupled geomorphological and ecohydrologicalorganization of river basins." Advances in Water Resources 28.1 (2005): 69-86.2. Zhou, Xiaochi, Erkan Istanbulluoglu, and Enrique R. Vivoni. "Modeling the ecohydrologicalrole of aspect‐controlled radiation on tree‐grass‐shrub coexistence in a semiarid climate." Water Resources Research 49, no. 5 (2013): 2872-2895. CONCLUSIONS To increase computational efficiency ecohydro- logically similar grids are developed into bins for soil moisture and water stress simulations. 10 slope bins X 12 aspect bins X 5 elevation bins X 4 vegetation type bins are used. Water stress is mapped from representative grid to actual (topography) grid annually. CA plant competition is driven by water stress Sample Area for Analysis PET & Precip Gradient: Year 2000 Precip Gradient: Year 2000 PET Gradient: Year 2000 Landlab Driver for this Analysis Fig. 6: Modeled elevation dependent vegetation organization in a catchment in central New Mexico This study demonstrates a preliminary evaluation of Landlab: Ecohydrology in Central New Mexico. The model shows general agreement with observed aspect-dependent and elevation-dependent


Transferencia de energía en NP de polímeros conjugados: modelado y contraste con datos experimentales. Rodrigo A. Ponzio1.2.*, Franco N. Bellomo1.†, Lucas E. Bellomo1.‡, Daniel A. Bellomo3, Rodrigo E. Palacios2 1. Dpto. de Física, FCEFQyN, UNRC 2. Dpto. de Química, FCEFQyN, UNRC 3. UTI, UNRC *rponzio@exa.unrc.edu.ar †fnbellomo@protonmail.com ‡lbellomo@protonmail.com 1. Introducción 3. Propiedades de la NP 4. Eficiencia de Desactivación Agradecimientos y Ref. • A la organización de la Escuela Giambiagi por otorgarnos las ayudas económicas. • Rodrigo A. Ponzio posee una beca interna doctoral de CONICET. • Rodrigo E. Palacios es miembro de la carrera de investigador científico (CIC) del CONICET. • Este trabajo fue financiado por: ANPCyT (PRH23 PICT 140/08, PME), ANPCyT-CONICyT (PICT 2691/11), SECyT UNRC (PPI/10) MINCyT Córdoba (PID 033/2010) • Al Unidad de Tecnología de la Información (UTI) UNRC y al Centro de Cómputos de Alto Rendimiento - CONICET Rosario. • Al Dr. Federico Agazzi. 2. Algoritmo de generación de puntos en una esfera Fig. 2 Puntos distribuidos en la superficie. Siendo R el radio de la NP y U una variable aleatoria (v.a.) uniforme en (0, 1) para la generación volumétrica o 1 para el caso superficial. X1, X2, X3 son v.a.i. normales. Fig. 1 Puntos distribuidos en todo el volumen. 3. Modelado de Transferencia de Energía • Los resultados de las simulaciones reproducen satisfactoriamente los resultados experimentales utilizando valores de y iguales para tres sistemas con distintos dopantes. • Se contrastará con datos experimentales simulaciones de NPs dopadas superficialmente. El grupo de Fotoquímica de la UNRC posee experiencia en la síntesis de NPs dopadas superficialmente y ya se dispone de los resultados experimentales necesarios para realizar esta comparación con la simulación. • Se ampliará el algoritmo de TEN para tener en cuenta la distribución real de tamaños de NP, y no sólo su tamaño medio. Dicha distribución ya ha sido medida por nuestro grupo utilizando un Microscopio de Fuerza Atómica. 6. Conclusiones y Proyecciones 5.Resultados 1- Se generan X dopantes en la NP, donde X viene dado por la densidad de dopaje de la NP. El excitón se genera con la misma probabilidad en cualquier punto de la NP debido a que la longitud de penetración de la luz de excitación es mucho más grande que el diámetro de la NP, por lo que la intensidad del haz de luz se puede asumir constante en todo su volumen (Fig. 3). 2- Se calcula la probabilidad de transferencia del excitón a cualquier dopante (Eq. 2) asumiendo un mecanismo de TE de tipo Förster (Eq. 3) que depende de la distancia a cada uno de estos (Fig. 4) de la forma: Fig. 3 Generación de dopantes y excitón en la NP Los polímeros conjugados son macromoléculas compuestas por monómeros que presentan enlaces simples y múltiples alternados. Dentro de la cadena existen segmentos (cromóforos) de longitud variable en donde los electrones π se encuentran deslocalizados. Debido a la heterogeneidad estructural de estos materiales, los procesos de transferencia de energía (TE) entre cromóforos y dopantes son altamente complejos. El mejor entendimiento de estos procesos es de importancia para el desarrollo de dispositivos orgánicos-electrónicos1. En este trabajo se presentan simulaciones de Monte Carlo realizadas con TEN (Trasnferencia de Energía en NanoParticulas) y su validación con datos experimentales2. TEN es sofware libre disponible en github3 implementado en python, desarollado por el Laboratorio de Microscopia Óptica Avanzada de la UNRC. Las librerías utilizadas son Numpy4, Matplotlib5 y MPI4py6, con este última paralelizandolo para poder correr en el cluster. Poster Nº24 Fig. 4 Distancia del excitón a los dopantes. Fig. 5 Paso aleatorio del excitón. 3- Se generan números aleatorios que se comparan con las probabilidades de los dos procesos para determinar si el excitón ha experimentado un decaimiento o se a transferido a un dopante, terminando la trayectoria. De no ser así, el ex


Customized workflow development and data integration concepts in Systems Medicine Markus Wolfien markus.wolfien@uni-rostock.de Gustav Steinhoff gustav.steinhoff@med.uni-rostock.de Olaf Wolkenhauer olaf.wolkenhauer@uni-rostock.de www.sbi.uni-rostock.de References [1] Lott SC, Wolfien M, Riege K, Bagnacani A, Wolkenhauer O, Hoffmann S, Hess WR. Customized workflow development and data modularization concepts for RNA-Sequencing and metatranscriptome experiments. Journal of Biotechnology. 2017 doi.org/10.1016/j.jbiotec.2017.06.1203 [2] Wolfien M, Rimmbach R, Schmitz U, Jung JJ, Krebs S, Steinhoff G, David R, Wolkenhauer O. TRAPLINE: A standardized and automated pipeline for RNA sequencing data analysis, evaluation and annotation. BMC Bioinformatics. 2016. doi: 10.1186/s12859-015-0873-9. [3] Steinhoff G, Nesteruk J, Wolfien M, Kundt G, The PERFECT Trial Investigators. Cardiac Function Improvement and Bone Marrow Response Outcome Analysis of the Randomized Perfect Phase III Clinical Trial of Intramyocardial CD133 + Application After Myocardial Infarction. EBioMedicine. 2017. doi.org/10.1016/j.ebiom.2017.07.022 Workflows: Symbiosis of research and tool integration for clinical application What is TRAPLINE? bit.ly/TRAPLINE_RNAseq 0 Integrating data using a Systems Medicine approach Systems Biology Data integration (DisGeNet, miRCancer, TriplexRNA, …) ATCATG101000111 TAGTG101010101111 TTCATAA00011011 AAGCA1010011 Statistics Evaluation of omics data (RPKM, FDR, Bayes, …) Bioinformatics Automated and scalable data processing, e.g. TRAPLINE [2] Med. Informatics Data management Clinic Improved diagnosis, prognosis and therapy Unexplained symptoms New insights mRNA1 miRNA1 mRNA2 miRNA2 mRNA3 Up regulated Down regulated Disease associated GO term 101000111ATCATG 101010101111TTCATAA 00011011AAGCA 1010011TAGTG 0 -10 10 log2(fold change) significant yes no 0 1 2 3 4 -log10(p value) Disease Biomarkers miRNA 2 mRNA 1 miRNA 1 mRNA 2 mRNA 3 Machine learning Data classification and prediction Application of the integrative workflow: The Phase III clinical trial PERFECT Workflow management frameworks and cloud computing services are bridging the gap between tool developers and end users, aiming towards an easy applicable and up-scalable computational data analysis. This in turn allows for an improved data reproducibility, process documentation, and monitoring of submitted jobs. Finally, workflows facilitate the use of state-of-the-art computational tools which would be hard to access for non-experts without graphical user interface frameworks. However, the use of workflows could be even more simplified for experimental and clinical researchers by strengthening the specific focus on the addressed research hypothesis and lessening the effort for the selection of the most appropriate tool [1]. Regenerative therapies using stem cells for the repair of heart tissue have been at the forefront of preclinical and clinical development during the past 16 years. To build upon this progress, the Phase III clinical trial PERFECT was designed to assess clinical safety and efficacy of intramyocardial CD133+ bone marrow stem cell treatment combined with coronary artery bypass graft (CABG) for induction of cardiac repair. The primary endpoint was delta left ventricular ejection fraction (∆LVEF) at 180 days compared to baseline measured with magnet resonance imaging (MRI). Responders (R) classified by ∆LVEF ≥5% after 180 d were 60% of the patients (35/58) in both treatment groups (+17.1% in R vs. non-responders (NR). The PERFECT trial shows that cardiac tissue repair and restitution of left ventricular function can be successfully installed in ischemic heart disease by CABG surgery associated with presence of enhanced circulating CD133+ and CD34+ EPC level. Using this new computer-aided diagnostic technology, responsive patient characteristics can be accurately identified prior to treatment with bypass surgery and stem cells [3]. Outcome results of the PERFECT trial.


Research goals The main goal will be a detailed analysis of the communication between Emperor Sigismund of Luxembourg and Nuremberg based on diplomatic materials. It will provide a diplomatic analysis of Sigismund‘s charters for Nuremberg combined with the question of how Nuremberg used its contacts to the emperor's court to win the ruler's favor. Combining the approaches from political communication and diplomatics with digital humanities, the project aims to discuss “new uses for an old science” (Duranti). Diplomatic analysis Includes the classic approach of studying the analytic dimension of charters (style, forms, chancery notes, etc.) and the genetic dimension, focusing on the phases of creation of the charters and persons involved. Digital Humanities Application of computer-based methods (primarily HTC and NLP) on an enhanced source corpus (including charters for burghers, Jews, burggrave of Nuremberg, etc.) for a comparison of the diplomatic material About this project Previous research verified close diplomatic and financial ties between Nuremberg and emperor Sigismund of Luxembourg. However, a study on political communication between both remains a desideratum. The many privileges issued by Sigismund for promise a valuable insight into the relationship between the emperor and one of his closest allies. They form the main subject of the following research- project, for which we applied to the Czech Science Foundation (GAČR) for three-year funding. The Communication between Sigismund of Luxembourg and the imperial city of Nuremberg Project Schedule 2025 Joint-organizing of a section at the Summer School Scriptorium Brunense in Brno focusing on Digital Humanities (summer) and an international Workshop on royal and imperial diplomatics concerning medieval towns (autumn/winter) 2026 Publication of two case studies 2027 Completion of a monograph by Stanislav Bárta and Tobias Heil Project details Project leader: Stanislav Bárta, PhD. (Brno) Co-researcher: Tobias Heil (Brno) Collaberative Partners: Regesta Imperii Branch Office Brno / Vienna States archive Nürnberg Dr. Daniel Luger (Graz, DiDip) as consultant Duration: 2025 – 2028 Funding (planned): Czech Science Foundation (GAČR) Contact: Tobias.Heil@mail.muni.cz Political communication Involves the reconstruction of the council’s network of contacts at the royal court and chancery with the help of accounting books and correspondence. This sheds light on the council’s active role during negotiations of privileges. Picture credits: Hidden Cat, miniature from Conrad of Megenberg, ‘Das Buch der Natur’, Germany ca. 1434. Strasbourg, Bibliothèque nationale et universitaire, Ms.2.264, fol. 85r (https://www.openculture.com/2022/10/cats-in- medieval-manuscripts-paintings.html); Sigismund of Luxembourg, miniature from Eberhard Windeck: Das Buch von Kaiser Sigismund, folio 212r (commons.wikimedia.org); Emperor Sigismunds charter for the city of Nuremberg (1433, May 31), StA Nürnberg, LosungA, Kaiserprivilegien, Nr. 337 (Digitalisat, Staatsarchiv Nürnberg); Nürnberg: miniature from Braun, Georg; Hogenberg, Franz; Novellanus, Simon: Beschreibung vnd Contrafactur der vornembster Stät der Welt, 1572, Köln 1582 (Digitalisat der Universitätsbibliothek Heidelberg) Tobias Heil, MA Institut of Auxilary Historical Science, and Archival Studies, Masaryk University, Brno Poster-presentation at the Summer School “Computational Language Technologies for Medievalists” Graz 8th – 12th of July 2024)


. . . . DasLabelingSystem–einfreierBaukasten fürkontrollierteVokabulare Michael Piotrowski, Florian Thiery, Kai-Christian Bruhn . . Problem . • Maschinenlesbare Annotationen sind Voraussetzung für semantische Verarbeitung von Daten. • Kontrollierte Vokabulare sind notwendig, um Annotationen maschinell verarbeitbar zu machen. • Kontrollierte Vokabulare abstrahieren von natürlichsprachlichen Ambiguitäten und Konnotationen: entscheidend für die semantische Verarbeitung von Forschungsdaten. • Für projektübergreifende Zusammenarbeit und semantischen Datenaustausch müssen Vokabulare nicht nur kontrolliert, sondern auch formell oder informell standardisiert sein. • Standardisierte kontrollierte Vokabulare ermöglichen Austausch, Kombination und gemeinsame Analyse annotierter Daten aus verschiedenen Quellen sowie Implementierung generischer Werkzeuge. • Erstellung und Wartung standardisierter kontrollierter Vokabulare sind jedoch teuer. • Alle beteiligten Parteien müssen zu gemeinsamem Verständnis der Begriffe kommen und Balance zwischen möglichst breiter Anwendbarkeit und möglichst präziser Analyse andereseits ﬁnden. • Ziele insbesondere in den Geisteswissenschaften schwierig zu erreichen: Potentielle Forschungsfragen extrem weit gefächert, Kategorisierung der Daten ist häuﬁg ein essenzieller Teil des Forschungsprozesses selbst. ➜Eklatanter Mangel an standardisierten kontrollierten Vokabularen in den Geisteswissenschaften. Digital-Humanities-Projekte sind gezwungen, eigene, projektspeziﬁsche Vokabulare zu deﬁnieren. Projektspeziﬁsche Vokabulare können internen Bedarf kurzfristig befriedigen, sind aber nicht interoperabel und verhindern zukünftigen Austausch und Nachnutzung annotierter Daten. . . Ansatz . Concept Concept Concept Concept Concept Concept Term Label Label ... Vocabulary Reference thesaurus Da es in der geisteswissenschaftlichen Forschung praktisch unmöglich ist, kontrollierte Vokabulare zu deﬁnieren, die alle denkbaren Anwendungen abdecken und generell akzeptiert sind, schlagen wir ein anderes Vorgehen vor. Bei unserem Ansatz deﬁnieren Projekte ihre eigenen Vokabulare, aber anstelle natürlichsprachlicher Deﬁnitionen werden die Terme mit einem oder mehreren Konzepten in einem Referenzthesaurus verknüpft. Der projektspeziﬁsche Term dient also quasi als »Label« für eine Menge gemeinsamer Konzepte. Dieser Ansatz ermöglicht es Projekten, Vokabulare entsprechend ihrer Bedürfnisse und unter Verwendung der im jeweiligen Forschungsgebiet üblichen Bezeichnun- gen benutzen, während gleichzeitig die Interoperabilität mit anderen Projekten über den Referenzthesaurus gewährleistet ist. . . Implementierung: Das Labeling System . Webanwendung, die es Benutzern ermög- licht, SKOS-Vokabulare zu erstellen und auf einfache Weise deren Terme mit einem oder mehreren Konzepten in einem oder mehreren Referenzthesauri zu verknüp- fen (broadMatch, narrowMatch, close- Match, exactMatch, relatedMatch, see- Also, sameAs und isDefinedBy). Die Benutzeroberﬂäche ermöglicht die Vi- sualisierung der deﬁnierten Vokabulare in einer Baumstruktur. Mit der CSV-Upload- Funktion kann ein CSV-Dokument hochge- laden werden, das mehrere prefLabels, altLabels, notes und definitions ei- nes Labels enthält und zudem Relatio- nen broader/narrower/related inner- halb von Vokabularen sowie die Links zu externen Ressourcen beschreibt. Externer Zugriff auf Vokabulare über SPARQL-Schnittstelle. Das Labeling System basiert auf ausgereif- ten Open-Source-Komponenten und ist selbst ebenfalls frei verfügbar. place types winery monastery inn church http://vocab.getty.edu/aat/300056005 - worship http://vocab.getty.edu/aat/300379053 – meal http://vocab.getty.edu/aat/300379053 – meal http://vocab.getty.edu/aat/300265204 – wine making http://vocab.getty.edu/aat/300056005 – worship http://vocab.getty.edu/aat/300265204 – wine making . . Institut für Raumbezogene Informations- und Messtechnik Hochschule Mainz University of Applied Sciences http://labeling.i3mainz.hs-mainz.de/ Michael P


Heavy neutral lepton (HNL) Heavy neutral lepton (HNL) production searches at NA62 production searches at NA62 XXVIII International Conference on Neutrino Physics and Astrophysics, Heidelberg, June 2018 Lorenza Iacobuzio, University of Birmingham - lorenza.iacobuzio@cern.ch Neutrino Minimal Standard Model Previous measurements HNL production searches at NA62 Event selection Data-MonteCarlo comparison SM extension accounting for baryon asymmetry of universe (BAU), dark matter (DM), neutrino masses and oscillations 3 additional right-handed, singlet, Majorana HNLs (not observed yet) N1 mass O(10 keV/c2), good DM candidate N2,3 mass O(1 GeV/c) [2] B(K+ → l+N) depends on BSM(K+ → l+ν), HNL-lepton coupling U 2 l4, and kinematic factor [2] Fixed-target experiment at CERN SPS: SPS 400 GeV/c p beam onto Be target → 75 GeV/c K+ In-flight K+ decays in 60 m long fiducial volume (FV) Data taking (2015-2018) with possibility to extend beyond 2021 Measure B(K+ → π+νν) with 20% precision to study CKM matrix element Vtd Perform hidden sector searches in presence of K+ beam (axions, dark photons, HNLs) Minimum bias run (2015) [1]: Data collected during 1.2·104 SPS spills (about 3 s effective spill) 0.4% - 1.3% of nominal beam intensity (3.3·1012 protons on target per spill) HNL production searches in kaon decays [1]: Kaons tagged with upstream Cherenkov detector (70 ps time resolution) Lepton tracks reconstructed in downstream spectrometer (130 μm spatial resolution) Particle ID with downstream Cherenkov detector, spectrometer and calorimeters One positive track with momentum in (5, 70) GeV/c, in time with kaon No extra activity in photon veto systems Positrons and muons identified through energy-momentum ratio [1] Squared missing mass: m2 miss = (PK - Pl)2 (SM K+ → l+ν peak at m2 miss = 0) HNL signal regions: 170 < mmiss < 448 MeV/c2 for K+ → e+N and 250 < mmiss < 373 MeV/c2 for K+ → μ+N [1] [2] JHEP0710:015 (2007) [3] Physical Review D 91, 052001 (2015) [4] Physical Review Letters 49, 18 (1982) [5] Physics Letters B 772, 712–718 (2017) ν M S M p a r t i c l e z o o l o g y NA62 schematic layout. HNL signal topology is visible ● PMNS mixing matrix between ● HNL flavour and mass eigenstates ● Expected and observed UL (at 90% CL) from NA62 2007 data-taking [4] Production searches: Look for peaks in missing mass distribution Decay-model independent Sensitive to long-lived HNLs Previous measurements in K + → μ+N 90% CL upper limits (UL) on HNL-muon coupling U 2 μ: KEK E089 (1982) [3]: (10 6 −, 10 4 −) for mN in (70, 300) MeV/c2 BNL E949 (2015) [4]: (10 9 −, 10 7 −) for mN in (175, 300) MeV/c2 NA62 (2017) [5]: (2·10 6 −, 10 5 −) for mN in (300, 375) MeV/c2 ● Expected and observed number of events: K+ → e+N (left) and K+ → μ+N (right) [2] ● Squared missing mass distributions for data and simulated events passing the e+ (left) and μ+ (right) selections [2] Technique, results and future prospects ● Squared missing mass distributions for data and simulated events passing the e+ (left) and μ+ (right) selections [2] Mass scans performed in HNL signal regions with step size of 1 MeV/c2 For each HNL mass hypothesis, background evaluated from sidebands of data mmiss distribution No statistically significant HNL production signal observed UL on B(K+ → l+N) established for each HNL mass hypothesis UL on coupling computed from UL on BR UL on |U2 e| in (10 7 −, 10 6 −) for mN in (170, 448) MeV/c2 and on |U2 μ| in (10 7 −, 10 6 −) for mN in (250, 373) MeV/c2 [1] Results improve world existing limits on HNL production searches on |U2 e| (over whole mass range) and on |U2 μ| (for masses above 300 MeV/c2) 2016-2018 data collected by NA62 much larger than 2015 sample Opportunity to further improve existing limits on |U2 e| and |U2 μ| Published in Physics Letters B 778, 137–145 (2018) [1]


PROVISIONAL FINDINGS - Emergency Laws are Political Legal Regimes They are not temporary but permanently incorporated into the legal system 1. 2. They are performative, to declare them is also to create the emergency 3. They are under- performing War - First World War Insurgency - Algerian War Terrorist Threat - 2015-2016 Dictatorship - Vichy’s Government Riots & Violences - 1985 New Caledonia - Kanaky Disaster - COVID-19 How to react when the state security, when the public order is threatened? When the legal frame appears insuficient to properly answer to an unexpected crisis so important that it could lead to the political and social unstability of the nation? In these situation , the State often end up relying on Emergency measures taking the form of regimes of exception. Through Legal History, and with fundamental interdisciplinary elements from sociology and from political sciences, the goal of this research is to analyse these exceptionnal regimes through their applications in France in the last century. It analyses, by observing ke y periods of the application of emergency laws, how did they impact the legal frame of normalcy, the Fundamental Rights and Legal a nd Political Thought in general ? Louis Bremond louis.bremond@UGent.be WHAT ? - Case Study of applied Emergency Laws WHEN ? - 1914-2024 WHERE ? - France, its territories and its former colonies Taming the Black Swans A Century of Law and Emergency in France 4. They are “field regime” and variates greatly depending on the context