Update README.md

README.md

@@ -113,8 +113,11 @@ configs:
 Clinical diagnosis of the eye is performed over multifarious data modalities including scalar clinical labels, vectorized biomarkers, two-dimensional fundus images, and three-dimensional Optical Coherence Tomography (OCT) scans. While the clinical labels, fundus images and OCT scans are instrumental measurements, the vectorized biomarkers are interpreted attributes from the other measurements. Clinical practitioners use all these data modalities for diagnosing and treating eye diseases like Diabetic Retinopathy (DR) or Diabetic Macular Edema (DME). Enabling usage of machine learning algorithms within the ophthalmic medical domain requires research into the relationships and interactions between these relevant data modalities. Existing datasets are limited in that: ($i$) they view the problem as disease prediction without assessing biomarkers, and ($ii$) they do not consider the explicit relationship among all four data modalities over the treatment period. In this paper, we introduce the Ophthalmic Labels for Investigating Visual Eye Semantics (OLIVES) dataset that addresses the above limitations. This is the first OCT and fundus dataset that includes clinical labels, biomarker labels, and time-series patient treatment information from associated clinical trials. The dataset consists of $1268$ fundus eye images each with $49$ OCT scans, and $16$ biomarkers, along with $3$ clinical labels and a disease diagnosis of DR or DME. In total, there are 96 eyes' data averaged over a period of at least two years with each eye treated for an average of 66 weeks and 7 injections. OLIVES dataset has advantages in other fields of machine learning research including self-supervised learning as it provides alternate augmentation schemes that are medically grounded.
 
 ## Subsets
-There are 3 subsets included in this dataset:
+There are 2 subsets included in this dataset:
 - Disease Classification (`disease_classification`)
+- Biomarker Detection ('biomarker_detection')
+
+Disease classification provides the full dataset while the biomarker detection subset provides a curated train-test split.
 
 ### Disease Classification
 This subset contains information regarding 78,000+ OCT scans obtained from a series of visits patients performed. In terms of labels, there are:
@@ -146,6 +149,23 @@ This information can be used to classify the disease. In addition, the first and
 - `SHRM`: Subretinal Hyperreflective Material
 - `Eye_ID`: A value to help distinguish different eye scans
 
+### Biomarker Detection
+This subset was used to host the 2023 Video and Image Processing Cup (VIP) challenge hosted by IEEE Signal Processing Society. The goal is to detect 6 biomarkers given image and clinical label data. For additional information reagarding the challenge, the metrics, the train-test data splits, please visit: https://alregib.ece.gatech.edu/competitions/2023-vip-cup/ 
+The 6 biomarkers and their associated interpretations:
+
+- **B1 (Intraretinal Hyperreflective Foci (IRHRF)):** were indicated as present with the appearance of intraretinal, highly reflective spots, which correspond pathologically to microaneurysms or hard exudates, with or without shadowing of the more posterior retinal layers.
+
+- **B2 (A Partially Attached Vitreous Face (PAVF)):** was indicated as present with evidence of perifoveal detachment of the vitreous from the internal limiting membrane (ILM) with a macular attachment point within a 3-mm radius of the fovea.
+
+- **B3 (A Fully Attached Vitreous Face (FAVF)):** was indicated as present with no evidence of perifoveal or macular detachment from the ILM.
+
+- **B4 (Intraretinal Fluid (IRF)):** was indicated as present when intraretinal hyporeflective areas or cysts had a minimum fluid height of 20 µm
+
+- **B5 (Diffuse Retinal Thickening or Diabetic Macular Edema (DRT/ME)):** was indicated as present when there was increased retinal thickness of 50 µm above the otherwise flat retina surface with associated reduced reflectivity in the intraretinal tissues
+
+- **B6 (Vitreous Debris (VD)):** was indicated as present with evidence of hyperreflective foci in the vitreous or shadowing of the retinal layers in the absence of an intraretinal hemorrhage.
+
+The 6 biomarkers are chosen to have balanced train-test splits.
 
 ## Data Download
 Sample code to download the disease classification dataset:
@@ -177,11 +197,14 @@ print(olives[0]['VMT'])
 
 **Associated Website**: https://alregib.ece.gatech.edu/
 
-**Paper**: https://arxiv.org/pdf/2209.11195
+**Paper**: 
+
+1. OLIVES Dataset: https://arxiv.org/pdf/2209.11195
+2. VIP Cup Paper: https://arxiv.org/pdf/2408.11170
 
 ## Citations
 
-If you find the work useful, please include the following citation in your work:
+If you find the work useful, please include the following citations in your work:
 
 > @inproceedings{prabhushankarolives2022,\
 >     title={OLIVES Dataset: Ophthalmic Labels for Investigating Visual Eye Semantics},\
@@ -189,3 +212,14 @@ If you find the work useful, please include the following citation in your work:
 >     booktitle={Proceedings of the Neural Information Processing Systems Track on Datasets and Benchmarks 2 (NeurIPS Datasets and Benchmarks 2022)},\
 >     year={2022}\
 > }
+>
+> @article{alregib2024ophthalmic,
+  title={Ophthalmic Biomarker Detection: Highlights From the IEEE Video and Image Processing Cup 2023 Student Competition [SP Competitions]},
+  author={AlRegib, Ghassan and Prabhushankar, Mohit and Kokilepersaud, Kiran and Chowdhury, Prithwijit and Fowler, Zoe and Corona, Stephanie Trejo and Thomaz, Lucas A and Majumdar, Angshul},
+  journal={IEEE Signal Processing Magazine},
+  volume={41},
+  number={4},
+  pages={96--104},
+  year={2024},
+  publisher={IEEE}
+}