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tuberculosis_metadata.json

@@ -5,7 +5,7 @@
     "GPL9790_platform": "https://ftp.ncbi.nlm.nih.gov/geo/platforms/GPL9nnn/GPL9790/soft/GPL9790_family.soft.gz",
     "UniProt_H37Rv_proteome": "https://rest.uniprot.org/uniprotkb/stream?query=proteome:UP000001584&fields=accession,reviewed,gene_oln&format=tsv"
   },
-  "download_timestamp": "2026-06-30T11:57:18.314708",
+  "download_timestamp": "2026-10-27T00:52:07.626302",
   "statistics": {
     "num_samples": 561,
     "num_features": 3814,
@@ -25,5 +25,5 @@
       }
     }
   },
-  "preprocessing_notes": "GSE19433 M. tuberculosis full-proteome antibody microarray (platform GPL9790, log-transformed raw intensities without normalization). The classification target is the M. tuberculosis culture result (0=NEG, 1=POS); samples with culture \"not applicable\" are dropped. Microarray spot ids (block_row_column) are mapped to M. tuberculosis ORFs (Rv locus tags) via the GPL9790 platform table; array-specific segment/alt spots (\"-s1\", \"-alt\") are collapsed to the base locus tag by averaging. Rv locus tags are mapped to UniProt accessions via the H37Rv reference proteome (UP000001584); spots that do not resolve to a UniProt accession are discarded."
+  "preprocessing_notes": "GSE19433 M. tuberculosis full-proteome antibody microarray (platform GPL9790, log-transformed raw intensities without normalization). The classification target is the M. tuberculosis culture result (0=NEG, 1=POS); samples with culture \"not applicable\" are dropped. Microarray spot ids (block_row_column) are mapped to M. tuberculosis ORFs (Rv locus tags) via the GPL9790 platform table; array-specific segment/alt spots (\"-s1\", \"-alt\") are collapsed to the base locus tag by averaging. Rv locus tags are mapped to UniProt accessions via the H37Rv reference proteome (UP000001584); spots that do not resolve to a UniProt accession are discarded. tuberculosis_batches.parquet holds the country of serum collection per sample; culture positivity differs sharply by country, so k-fold splits keep countries unmixed."
 }