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tuberculosis_metadata.json

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+{
+  "dataset_name": "tuberculosis",
+  "download_urls": {
+    "GSE19433": "https://ftp.ncbi.nlm.nih.gov/geo/series/GSE19nnn/GSE19433/matrix/GSE19433_series_matrix.txt.gz",
+    "GPL9790_platform": "https://ftp.ncbi.nlm.nih.gov/geo/platforms/GPL9nnn/GPL9790/soft/GPL9790_family.soft.gz",
+    "UniProt_H37Rv_proteome": "https://rest.uniprot.org/uniprotkb/stream?query=proteome:UP000001584&fields=accession,reviewed,gene_oln&format=tsv"
+  },
+  "download_timestamp": "2026-06-25T13:26:30.281407",
+  "statistics": {
+    "num_samples": 508,
+    "num_features": 3814,
+    "target_stats": {
+      "class_mapping": {
+        "NORMAL": 0,
+        "ABNORMAL": 1
+      },
+      "num_classes": 2,
+      "class_names": [
+        "NORMAL",
+        "ABNORMAL"
+      ],
+      "samples_per_class": {
+        "NORMAL": 159,
+        "ABNORMAL": 349
+      }
+    }
+  },
+  "preprocessing_notes": "GSE19433 M. tuberculosis full-proteome antibody microarray (platform GPL9790, log-transformed median spot intensities). The classification target is the patient chest x-ray result (0=NORMAL, 1=ABNORMAL); samples with chest x-ray \"not applicable\" or \"UNKNOWN\" are dropped. Microarray spot ids (block_row_column) are mapped to M. tuberculosis ORFs (Rv locus tags) via the GPL9790 platform table; array-specific segment/alt spots (\"-s1\", \"-alt\") are collapsed to the base locus tag by averaging. Rv locus tags are mapped to UniProt accessions via the H37Rv reference proteome (UP000001584); spots that do not resolve to a UniProt accession are discarded."
+}