Datasets:
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README.md
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---
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license: cc-by-4.0
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tags:
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- biology
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- genomics
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- proteomics
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- graph-neural-networks
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- benchmarking
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- omics
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pretty_name: OgBench — Omics Graph Benchmark
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task_categories:
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- tabular-classification
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size_categories:
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- n<1K
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---
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# OgBench: Benchmarking Graph Neural Networks on Omics Data
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OgBench is the first benchmark suite for graph-level prediction in the
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**n ≪ p regime** characteristic of omics data, where the number of
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patient samples n is much smaller than the number of nodes (genes or
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proteins) p per graph.
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## Datasets
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This repository contains four preprocessed omics graph classification
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datasets:
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| Dataset | Modality | n | p | Task |
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|---|---|---|---|---|
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| HERITAGE | Proteomics | 654 | 4,977 | Exercise responder (binary) |
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| Parkinson's | Transcriptomics | 535 | 21,755 | Cognitive status (binary) |
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| AddNeuroMed | Transcriptomics | 711 | 17,198 | Clinical diagnosis (3-class) |
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| BRCA | Epigenomics | 640 | 19,049 | Cancer subtype (4-class) |
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## Source Data
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- **HERITAGE**: Robbins et al. (2021), *Nature Metabolism*. Available
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via MoTrPAC Data Hub (motrpac-data.org) under CC-BY 4.0.
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- **Parkinson's**: Shamir et al. (2017), *Neurology*. Available via
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NCBI GEO (GSE99039) under GEO public data access policy.
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- **AddNeuroMed**: Lovestone et al. (2009). Available via NCBI GEO
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(GSE63063) under GEO public data access policy.
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- **BRCA**: Yang et al. (2025), MLOmics, *Scientific Data*. Available
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on Figshare/Hugging Face under CC-BY 4.0.
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## Preprocessing
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All datasets are preprocessed with a consistent pipeline including
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probe-to-gene aggregation, normalization, and covariate adjustment.
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Full preprocessing details are provided in Appendix B of the
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accompanying paper. Graphs are split 70/15/15 (train/val/test) with
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a fixed random seed.
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