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+ ---
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+ license: cc-by-4.0
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+ tags:
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+ - biology
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+ - genomics
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+ - proteomics
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+ - graph-neural-networks
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+ - benchmarking
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+ - omics
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+ pretty_name: OgBench — Omics Graph Benchmark
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+ task_categories:
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+ - tabular-classification
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+ size_categories:
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+ - n<1K
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+ ---
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+
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+ # OgBench: Benchmarking Graph Neural Networks on Omics Data
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+
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+ OgBench is the first benchmark suite for graph-level prediction in the
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+ **n ≪ p regime** characteristic of omics data, where the number of
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+ patient samples n is much smaller than the number of nodes (genes or
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+ proteins) p per graph.
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+
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+ ## Datasets
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+
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+ This repository contains four preprocessed omics graph classification
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+ datasets:
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+
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+ | Dataset | Modality | n | p | Task |
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+ |---|---|---|---|---|
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+ | HERITAGE | Proteomics | 654 | 4,977 | Exercise responder (binary) |
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+ | Parkinson's | Transcriptomics | 535 | 21,755 | Cognitive status (binary) |
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+ | AddNeuroMed | Transcriptomics | 711 | 17,198 | Clinical diagnosis (3-class) |
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+ | BRCA | Epigenomics | 640 | 19,049 | Cancer subtype (4-class) |
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+
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+ ## Source Data
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+
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+ - **HERITAGE**: Robbins et al. (2021), *Nature Metabolism*. Available
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+ via MoTrPAC Data Hub (motrpac-data.org) under CC-BY 4.0.
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+ - **Parkinson's**: Shamir et al. (2017), *Neurology*. Available via
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+ NCBI GEO (GSE99039) under GEO public data access policy.
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+ - **AddNeuroMed**: Lovestone et al. (2009). Available via NCBI GEO
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+ (GSE63063) under GEO public data access policy.
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+ - **BRCA**: Yang et al. (2025), MLOmics, *Scientific Data*. Available
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+ on Figshare/Hugging Face under CC-BY 4.0.
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+
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+ ## Preprocessing
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+
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+ All datasets are preprocessed with a consistent pipeline including
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+ probe-to-gene aggregation, normalization, and covariate adjustment.
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+ Full preprocessing details are provided in Appendix B of the
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+ accompanying paper. Graphs are split 70/15/15 (train/val/test) with
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+ a fixed random seed.