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README.md
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# ClinVar Variant Effect Prediction Benchmark
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## Dataset Description
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### Model Scores
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The remaining columns contain precomputed variant effect scores, one per model. These span genomic, RNA, and protein foundation models — including Evo 2 (7B and 40B), Evo, Nucleotide Transformer, CodonBERT, EnCodon, CaLM, ESM-2, ESM-1b, and RNA-FM as well as splice effect predictors (SpliceAI, Pangolin) and other baselines such as AlphaMissense, GPN-MSA, CADD, and phyloP conservation scores (100/241/447/470-way alignments).
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---
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task_categories:
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- zero-shot-classification
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pretty_name: ClinVar
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size_categories:
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- 100K<n<1M
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---
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# ClinVar Variant Effect Prediction Benchmark
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## Dataset Description
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### Model Scores
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The remaining columns contain precomputed variant effect scores, one per model. These span genomic, RNA, and protein foundation models — including Evo 2 (7B and 40B), Evo, Nucleotide Transformer, CodonBERT, EnCodon, CaLM, ESM-2, ESM-1b, and RNA-FM as well as splice effect predictors (SpliceAI, Pangolin) and other baselines such as AlphaMissense, GPN-MSA, CADD, and phyloP conservation scores (100/241/447/470-way alignments).
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