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<|newrecord|> nctId: NCT06371365 id: KMUHIRB-E(II)-20220204 briefTitle: Adverse Events for Free Flap Surgery in Head and Neck Cancer overallStatus: COMPLETED date: 2022-10-19 date: 2023-09-24 date: 2023-09-24 date: 2024-04-17 date: 2024-04-18 name: Kaohsiung Medical University class: OTHER name: Kaohsiung Medical Unive... |
<|newrecord|> nctId: NCT06371352 id: JagiellonianU73 briefTitle: Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Depression overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-12 date: 2027-05 date: 2024-04-17 date: 2024-04-17 name: Jakub Antczak class: ... |
<|newrecord|> nctId: NCT06371339 id: 23 VADS 03 briefTitle: Optimization With a Gamma Camera of the Individualized Patient Dosimetry in Radioiodine Therapy of Thyroid Diseases acronym: THIDOS overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-06 date: 2024-04-17 date: 2024-04-17 name: Institut Cla... |
Its aim is to assess the feasibility of using this ambulatory gamma camera (MoTI) in the clinic in this patient population. The camera will be used to measure the 131I uptake/fixation rates during the thyroid scintigraphy. |
20 patients will be included in the study. conditions: Hyperthyroidism studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DEVICE_FEASIBILITY masking: NONE count: 20 type: ESTIMATED name: Additional acquisitions with the investigational gamma-camera " MoTI ". measure: The... |
<|newrecord|> nctId: NCT06371326 id: BJQLZT002004 briefTitle: A Study of ZT002 Injection in Participants With Overweight or Obesity overallStatus: ENROLLING_BY_INVITATION date: 2023-11-21 date: 2024-08-30 date: 2024-09-30 date: 2024-04-17 date: 2024-04-17 name: Beijing QL Biopharmaceutical Co.,Ltd class: INDUSTRY brief... |
<|newrecord|> nctId: NCT06371313 id: GuangdongWCH-LiLi03 briefTitle: Endocrine, Metabolic and Inflammatory Characteristics of Offspring of Mothers With PCOS Hyperandrogenism overallStatus: COMPLETED date: 2023-05-01 date: 2024-03-05 date: 2024-03-05 date: 2024-04-17 date: 2024-04-17 name: Guangdong Women and Children H... |
<|newrecord|> nctId: NCT06371300 id: HLS21156 briefTitle: Photobiomodulation With REd vs BluE Light (REBEL) overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-08 date: 2025-12 date: 2024-04-17 date: 2024-04-23 name: Aston University class: OTHER briefSummary: The use of photobiomodulation or low-level light the... |
Participants with dry eye disease, oil gland disruption and blepharitis will receive 3 treatments with these LLLT, each separted by 1 week apart, and followed up to 1 month after the final treatment session. Participants will be randomised to either of 3 groups: Red light only group, Red + Blue light group, or a sham t... |
<|newrecord|> nctId: NCT06371287 id: 64696022.1.0000.5346 briefTitle: Effect of Musical Auditory Training on Subjects With Tinnitus Disorder overallStatus: RECRUITING date: 2023-02-20 date: 2024-08-10 date: 2025-02-10 date: 2024-04-17 date: 2024-04-24 name: Universidade Federal de Santa Maria class: OTHER briefSummary:... |
<|newrecord|> nctId: NCT06371274 id: ZYYY-IIT-TNBC-001 briefTitle: A Study on the Efficacy and Safety of Oral All-trans Retinoic Acid Combined With Toripalimab in TNBC. overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-04-30 date: 2026-04-30 date: 2024-04-17 date: 2024-04-17 name: First Affiliated Hospital ... |
<|newrecord|> nctId: NCT06371261 id: 2023/CHU/07 briefTitle: Pathogenicity of Species of the Achromobacter Genus in Patients From Reunion Island With Cystic Fibrosis acronym: ACHROMO-MUCO overallStatus: RECRUITING date: 2024-02-29 date: 2027-03 date: 2027-03 date: 2024-04-17 date: 2024-04-26 name: Centre Hospitalier Un... |
However, until now, the identification of Achromobacter species has involved the use of molecular biology techniques that are not routinely applicable in diagnostic laboratories, limiting studies and the collection of epidemiological data. Recently, a database using MALDI-TOF mass spectrometry has been built for rapid ... |
In view of the local epidemiology and the current lack of data, it would be necessary and interesting to use this tool to study a cohort of cystic fibrosis patients in Réunion island (North and South sites) to see whether one species has a greater clinical impact than another (pathogenicity), and/or is more responsible... |
<|newrecord|> nctId: NCT06371248 id: 2850 briefTitle: Steady Feet: Preventing Falls in the Community overallStatus: COMPLETED date: 2018-11-19 date: 2019-12-20 date: 2019-12-20 date: 2024-04-17 date: 2024-04-17 name: Changi General Hospital class: OTHER briefSummary: The purpose of this study is to examine the feasibil... |
<|newrecord|> nctId: NCT06371235 id: 2024-A00739-38 briefTitle: Study of the Transmission of Anti-interferon Type 1 Alpha Autoantibodies From Mother to Child Via the Placental Barrier acronym: Pregiferon overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2024-09 date: 2027-03 date: 2024-04-17 date: 2024-04-17 name: ... |
<|newrecord|> nctId: NCT06371222 id: BSMMU/2023/6502 briefTitle: Role of Ivabradine on Heart Rate and Quality of Life in Patients With Mitral Stenosis in Sinus Rhythm overallStatus: COMPLETED date: 2023-02-01 date: 2024-01-31 date: 2024-02-01 date: 2024-04-17 date: 2024-04-17 name: Bangabandhu Sheikh Mujib Medical Univ... |
One of the hallmark features of mitral stenosis is the development of sinus rhythm, which can be associated with elevated heart rates due to decreased diastolic filling time and compensatory mechanisms to maintain cardiac output. Persistent tachycardia in patients with mitral stenosis contributes to increased myocardia... |
In recent years, ivabradine, a selective inhibitor of the If current in the sinoatrial node, has emerged as a promising therapeutic option for controlling heart rate in various cardiovascular conditions, including chronic heart failure and ischemic heart disease \[3\]. By specifically targeting the cardiac pacemaker ce... |
However, the role of ivabradine in patients with mitral stenosis in sinus rhythm remains uncertain, and there is limited evidence regarding its efficacy and impact on QoL in this specific patient population. Therefore, the aim of this randomized controlled trial (RCT) is to investigate the effects of ivabradine on hear... |
<|newrecord|> nctId: NCT06371209 id: 2022P000619 briefTitle: Kinematics of Ewing Amputees overallStatus: ENROLLING_BY_INVITATION date: 2022-05-17 date: 2024-06-29 date: 2024-07-01 date: 2024-04-17 date: 2024-04-17 name: Brigham and Women's Hospital class: OTHER briefSummary: The agonist-antagonist myoneural interface (... |
The aim of this research protocol is to evaluate the electromyographic and kinematic patterns of participants who have undergone unilateral lower extremity Ewing Amputation in order to determine how similar their residual limb data is when compared to their intact limb data. A secondary aim of this research may include... |
The investigators hypothesize that the affected limb of patients with the Ewing procedure will demonstrate a pattern of electromyographic activation of their AMI constructs and kinematic data that recapitulates the pattern seen in their intact limb. The investigators secondarily hypothesize that the kinematic assessmen... |
<|newrecord|> nctId: NCT06371196 id: BBD-PBC 2024-03 briefTitle: Clinical Study on the Treatment of Elevated Total Bilirubin in Primary Biliary Cholangitis With Baobao Dan Capsule overallStatus: NOT_YET_RECRUITING date: 2024-04-25 date: 2025-07-25 date: 2025-12-31 date: 2024-04-17 date: 2024-04-17 name: Mei Han class: ... |
2. To observe the positive intervention effect of Babaodan Capsule on the clinical symptoms of primary biliary cholangitis patients with elevated total bilirubin. conditions: Primary Biliary Cholangitis studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT mas... |
<|newrecord|> nctId: NCT06371183 id: AOMSaidB briefTitle: A Comparative Study of Clinical, Endoscopic and Histopathological Features of Colitis in Children on June 2024 overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-05-30 date: 2027-05-30 date: 2024-04-17 date: 2024-04-17 name: Assiut University class: O... |
<|newrecord|> nctId: NCT06371170 id: CCPC- 001/22 briefTitle: Rivaroxaban for Intracardiac Thrombosis in the Pediatric Population overallStatus: RECRUITING date: 2023-01-01 date: 2025-01-01 date: 2027-01-01 date: 2024-04-17 date: 2024-04-19 name: Azienda Ospedaliero, Universitaria Ospedali Riuniti class: OTHER briefSum... |
Participants already taking rivaroxaban as part of their regular medical care for thrombosis resolution. They will undergo monthly visits to check that the treatment is progressing correctly and that no major bleeding has occurred. After 3 months of treatment, they will repeat the radiological imaging investigation to ... |
<|newrecord|> nctId: NCT06371157 id: AK104-308 briefTitle: A Study of AK104+Lenvatinib in Combination With Transarterial Chemoembolization (TACE) Versus TACE in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma overallStatus: NOT_YET_RECRUITING date: 2024-07-02 date: 2025-10-25 date: 2026-05-23 date: ... |
<|newrecord|> nctId: NCT06371144 id: NHREC/16/05/22/130 briefTitle: A Randomized Control Trial on Intravenous Paracetamol Versus Intramuscular Tramadol as Intra Partum Labor Analgesia overallStatus: COMPLETED date: 2022-06-03 date: 2022-09-10 date: 2022-09-10 date: 2024-04-17 date: 2024-04-17 name: Darlington-Peter Chi... |
OBJECTIVE: To compare intravenous paracetamol versus intramuscular tramadol as labour analgesia and to evaluate the incidence of side effects on mother and baby of both drugs. |
METHOD: This would be a hospital based randomized controlled trial comparing intravenous paracetamol to intramuscular tramadol as labour analgesia in pregnant women in active phase of labour in the department of obstetrics and gynecology at Alex-Ekwueme Federal University Teaching Hospital and St. Patrick Mile 4 hospit... |
10 ANALYSIS AND RESULTS: Data will be collated, tabulated and then statistically analyzed using Statistical Package for Social Science (IBM SPSS) software (version 24, Chicago II, USA). Continuous variables will be presented as mean and standard deviation (Mean ± 2SD) or median and range as appropriate, while categoric... |
<|newrecord|> nctId: NCT06371131 id: PONV of Thyroid Surgery briefTitle: Effect of Stellate Ganglion Block on Postoperative Nausea and Vomiting overallStatus: RECRUITING date: 2023-04-17 date: 2024-05-30 date: 2024-08-30 date: 2024-04-17 date: 2024-04-26 name: The Second Affiliated Hospital of Chongqing Medical Univers... |
<|newrecord|> nctId: NCT06371118 id: PI 20210032 briefTitle: HPV Self-sampling for Women Who do Not Attend Cervical Cancer Screening Programme acronym: HERSELF overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-09 date: 2024-11 date: 2024-04-17 date: 2024-04-17 name: Universidade do Porto class: OTHER name: Uni... |
An experimental and population-based study will be implemented at three primary healthcare centers located in the Western Porto region: Cedofeita, Garcia de Orta, and Prelada. Eligible women will be randomized into a control group or an intervention group. The control group will correspond to the standard of care (invi... |
Self-sampling samples will be subjected to HPV genotyping. In parallel, high-risk HPV positive women will be called in by their family doctors to undergo screening in a clinical setting so that they can continue their clinical follow-up in the conventional pathway. conditions: Papillomavirus Infections conditions: Earl... |
<|newrecord|> nctId: NCT06371105 id: 014_2018 briefTitle: Aquatic_Training in Obese Women overallStatus: COMPLETED date: 2019-01-02 date: 2019-03-30 date: 2019-03-30 date: 2024-04-17 date: 2024-04-17 name: University of Taipei class: OTHER briefSummary: This study aims to assess the effects of 10-week water-based aerob... |
<|newrecord|> nctId: NCT06371092 id: 2023/01 briefTitle: Efficacy of a Desensitizing Agent During At-home Bleaching overallStatus: COMPLETED date: 2023-01-31 date: 2023-02-22 date: 2023-03-01 date: 2024-04-17 date: 2024-04-17 name: University of Santiago de Compostela class: OTHER briefSummary: The main objective of th... |
<|newrecord|> nctId: NCT06371079 id: NO-OVD-ICL briefTitle: Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs overallStatus: RECRUITING date: 2024-03-01 date: 2024-05-30 date: 2024-06 date: 2024-04-17 date: 2024-04-17 name: Loay Abdulmutalib Almusawi class: OTHER brief... |
The main question it aims to answer is that is it safe to do the surgery without using them? to answer this question researchers will access recorded data of patients that underwent refractive surgeries in a private clinic since 2017 and compare them as two groups: those who underwent the traditional procedures and tho... |
<|newrecord|> nctId: NCT06371066 id: EAkyuz-2 briefTitle: The Effect of Video-based Training on the Knowledge Levels of Nursing Students overallStatus: COMPLETED date: 2021-02-01 date: 2021-04-01 date: 2021-06-10 date: 2024-04-17 date: 2024-04-17 name: Kırıkkale University class: OTHER briefSummary: Although face-to-fa... |
<|newrecord|> nctId: NCT06371053 id: community - dementia briefTitle: The Effect of Community Intervention on Different Degrees of Dementia overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-05 date: 2024-05 date: 2024-04-17 date: 2024-04-17 name: Babujinaya Cela class: OTHER_GOV briefSummary: The goal of this ... |
<|newrecord|> nctId: NCT06371040 id: V1.0, CART-20230619 briefTitle: Safety and Efficacy of CD19-BCMA Targeted CAR-T Therapy for Refractory Generalized Myasthenia Gravis overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-03-01 date: 2026-12-01 date: 2024-04-17 date: 2024-04-17 name: Ting Chang, MD class: OTH... |
CD19-BCMA Targeted CAR-T Dose 2 1.5 e6/ kg CD19-BCMA CAR-T positive T cells |
CD19-BCMA Targeted CAR-T Dose 2 5 e6/ kg CD19-BCMA CAR-T positive T cells primaryPurpose: TREATMENT masking: NONE count: 12 type: ESTIMATED name: CD19-BCMA Targeted CAR-T Dose 1 name: CD19-BCMA Targeted CAR-T Dose 2 name: CD19-BCMA Targeted CAR-T Dose 2 measure: Frequency, type, and severity of adverse events measure: ... |
<|newrecord|> nctId: NCT06371027 id: RECO6U/22-2022 briefTitle: Novel Silk Fibroin Nanofiber Membrane Using Minimally Invasive Surgery in Treatment of Periodontal Intrabony Defects: A Randomized Clinical Trial overallStatus: COMPLETED date: 2022-11-01 date: 2024-02-15 date: 2024-04-01 date: 2024-04-17 date: 2024-04-17 ... |
<|newrecord|> nctId: NCT06371014 id: Ondansetron mouth soluble film briefTitle: Comparative Study on the Efficacy and Safety of Ondansetron Oral Membrane for the Prevention of Vomiting During Moderate Hypoemetic Chemotherapy acronym: Ondansetron overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-12-30 date: ... |
<|newrecord|> nctId: NCT06371001 id: Helicobacter Pyloi and CKD briefTitle: Prevalance Of Helicobacter Pylori Infection In Chonic Kidney Diseased Patient Admitted To Luxor Medical Complex overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2025-07-01 date: 2024-04-17 date: 2024-04-17 name: Assiut ... |
<|newrecord|> nctId: NCT06370988 id: 4343 briefTitle: Theta-Burst Stimulation for Bipolar Depression acronym: TRIBE overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2029-05 date: 2029-05 date: 2024-04-17 date: 2024-04-22 name: Centre for Addiction and Mental Health class: OTHER name: University Health Network, Tor... |
<|newrecord|> nctId: NCT06370975 id: Fluid resuscitation in trauma briefTitle: Effect of Fluid Resuscitation on Lactate in Traumatic Injury Patients overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2025-08 date: 2025-09 date: 2024-04-17 date: 2024-04-17 name: Assiut University class: OTHER briefSummary: The stu... |
Also to provide insights into the optimal fluid resuscitation strategy for traumatic injury patients conditions: Fluid Resuscitation studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: C... |
<|newrecord|> nctId: NCT06370962 id: 69HCL24_0076 id: 2024-A00343-44 type: OTHER domain: ID-RCB briefTitle: Circadian Rhythm Disorders in Children With Cystic Fibrosis Under CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Modulators acronym: CHRONO-MUCO overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2... |
Several studies have reported the possibility of respiratory and non-respiratory sleep disorders (SD) in patients with CF. Respiratory disorders are reported to affect 30% of children with CF (Barbosa 2020). Among non-respiratory SD, sleep onset and maintenance insomnia are well known in these patients, while chronotyp... |
The existence of chronotype abnormalities has been suggested in CF patients, but no precise data are available (Louis 2022). The involvement of CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) protein dysfunction in the central nervous system (CNS) has been hypothesized as a contributory factor. In vivo, in a... |
In the era of highly effective modulator therapy (HEMT) for the treatment of CF, the impact of these new therapies on chronotype has been understudied. Assuming that chronotype abnormalities are a direct consequence of CFTR protein dysfunction in the retina and anterior hypothalamus, HEMT should improve sleep quality. ... |
Paradoxically, the perceived gain in respiratory quality of life is counterbalanced by the occurrence of these disorders. Some patients would effectively reverse their treatment in order to limit the phenomenon. A single polysomnographic study evaluated the effect of HEMT Kaftrio-Kalydeco on sleep in adults with CF (We... |
The aim of this study is to evaluate the chronotype of children with CF treated with HEMT. Chronotype abnormalities could have major consequences for quality of life, the immune system, cognitive functions and metabolism. Systematic detection of these disorders via anamnesis, followed by diagnosis by questionnaire, act... |
<|newrecord|> nctId: NCT06370949 id: 2024-01/17 briefTitle: The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block acronym: TAP overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-09-30 date: 2024-11-30 date: 2024-04-17 date: 2024-04-17 name: Dr Abdu... |
Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries. conditions: Colorectal Cancer conditions: Colorectal Neoplasms studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIV... |
<|newrecord|> nctId: NCT06370936 id: NL84824.091.23 id: NL84824.091.23 type: OTHER domain: CCMO / Toetsingonline briefTitle: The EXPLAIN Study: Exploring Plant-Based Meat Analogues for Their Impact on Health acronym: EXPLAIN overallStatus: RECRUITING date: 2024-04 date: 2025-03 date: 2025-03 date: 2024-04-17 date: 2024... |
The primary objective of this clinical trial is to evaluate if and to what extent replacing all meat products in an average Dutch diet with currently commercially available PBMAs affects the systolic blood pressure of middle-aged men and women in a 2x8 week fully dietary controlled crossover intervention study. The sec... |
114 men and women with a BMI of 23-40 kg/m2, aged 45-75 years will be included in the study. Participants will follow both an 8-week completely controlled diet in which all meats are of plant-based origin (PBMAs) and an 8-week diet in which all meats are of animal origin in randomized order with a 10-week wash-out peri... |
<|newrecord|> nctId: NCT06370923 id: 1R01MH133488-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R01MH133488-01 briefTitle: Harnessing Male Peer Networks to Enhance Engagement With HIV Prevention acronym: IMPERATIVE overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2026-07 date: 2028-12 date: 2024-04-17 d... |
The objective of this project is to use an implementation science approach to establish the impact of HIVST distribution through male social networks, with phone-based support and improved risk perception, on PrEP (Pre-Exposure Prophylaxis) uptake among men in Eastern Zimbabwe. The project will leverage infrastructure ... |
The study will utilise a cluster randomised design of 44 clusters (22 Intervention:22 control) comprising on average 81 men in each cluster (total N = 3591) followed for 6 months (giving \>80% power to detect a difference in PrEP initiation among men of 2% versus 8.5%). In intervention clusters the investigators will i... |
<|newrecord|> nctId: NCT06370910 id: CAAE 58569421.5.0000.5327 briefTitle: Comparison Low-Level Laser Therapy With Cryotherapy in Parturients With Laceration and/or Episiotomy on Pain Reduction acronym: CL overallStatus: COMPLETED date: 2023-08-01 date: 2024-01-05 date: 2024-01-10 date: 2024-04-17 date: 2024-04-17 name... |
Objective: To compare the use of photobiomodulation with cryotherapy in the immediate postpartum period of 2 hours in parturients who suffered 1st and 2nd-degree lacerations and/or episiotomies. |
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