| { |
| "PICO": { |
| "P": "(\"Neonate\" OR \"Infant\") AND \"Endotracheal intubation\"", |
| "I": "(\"Video Imaging\" OR \"Videolaryngoscope\") AND \"Endotracheal intubation\"", |
| "C": "\"Endotracheal Intubation With Standard Laryngoscopic Guidance\"", |
| "O": "\"Intubation\" OR \"Airway Trauma\" OR \"Oxygen Saturation\" OR \"Adverse Event\"", |
| "S": "Randomized controlled trials (RCTs)", |
| "Details": { |
| "P Details": "INCLUSION: Neonates aged 0 to 28 days AND requiring endotracheal intubation AND intubated in hospital settings (delivery room OR neonatal intensive care unit OR operating room) AND randomized in trials comparing videolaryngoscopy with direct laryngoscopy; studies including older infants/children were eligible only if neonatal data were separately extractable.; EXCLUSION: Non-neonates OR mixed-age studies without separately extractable neonatal data OR studies with fewer than five neonates OR manikin/non-human studies; some included-study populations also excluded infants with facial OR airway anomalies, but this was not a review-level universal exclusion.", |
| "I Details": "INCLUSION: Randomized/quasi-randomized/cluster/cross-over studies AND neonates aged 0-28 days requiring endotracheal intubation in the delivery room OR NICU OR operating room AND comparison of videolaryngoscopy with any neonatal intubation device (e.g., C-MAC OR AirTraq OR GlideScope OR Truview OR modified videolaryngoscope used for shared-view coaching) versus direct laryngoscopy AND neonatal data separately extractable if mixed-age studies; EXCLUSION: Studies with no neonates OR fewer than five neonates OR neonatal data not separately extractable from older participants OR manikin/non-human studies", |
| "O Details": "INCLUSION: Outcomes assessed during AND/or immediately after neonatal endotracheal intubation attempts comparing videolaryngoscopy versus direct laryngoscopy, including at least one of: time to successful intubation (seconds) OR number of attempts OR first-attempt success OR desaturation/bradycardia during intubation OR lowest oxygen saturation during intubation OR airway trauma. Neonatal data had to be separately extractable when mixed-age studies were included.; EXCLUSION: Studies were excluded if neonatal outcome data were not separately extractable OR fewer than five neonates were included OR no human neonates were studied (e.g. manikin studies) OR there were no neonates in the sample. The review did not exclude studies solely for non-reporting of outcomes of interest." |
| } |
| }, |
| "trials": [ |
| { |
| "relation_type": "include", |
| "pmid": "26908701", |
| "has_rob": "True", |
| "study name": "Moussa 2016" |
| }, |
| { |
| "relation_type": "include", |
| "pmid": "26482669", |
| "has_rob": "True", |
| "study name": "O'Shea 2015" |
| }, |
| { |
| "relation_type": "include", |
| "pmid": "30692885", |
| "has_rob": "True", |
| "study name": "Salama 2019" |
| }, |
| { |
| "relation_type": "include", |
| "pmid": "19335346", |
| "has_rob": "True", |
| "study name": "Singh 2009" |
| }, |
| { |
| "relation_type": "include", |
| "pmid": "29985811", |
| "has_rob": "True", |
| "study name": "Tao 2019" |
| }, |
| { |
| "relation_type": "include", |
| "pmid": "29795452", |
| "has_rob": "True", |
| "study name": "Volz 2018" |
| } |
| ], |
| "study group": [ |
| { |
| "group num": "1.1", |
| "outcome": "Time required for successful intubation (seconds). Details: Total time in seconds from first insertion of the laryngoscope blade into the mouth until final confirmation of endotracheal tube placement by clinical examination and/or SpO2 increase and/or end-tidal CO2 and/or chest radiograph.", |
| "study arm": "Videolaryngoscopy (VDL) versus conventional direct laryngoscopy (CDL). Details: Intervention: videolaryngoscopy for neonatal endotracheal intubation using any neonatal video device (e.g., C-MAC, AirTraq, GlideScope/GlideScope cobalt, Truview, or modified Miller videolaryngoscope; including video-assisted teaching/coaching approaches where the instructor can share the airway view). Control: conventional direct laryngoscopy with a standard direct laryngoscope (e.g., Miller/standard neonatal laryngoscope, or video device screen covered so intubation proceeds as direct laryngoscopy).", |
| "Subgroup": "", |
| "Data type": "Continuous", |
| "Effect measure": "Mean Difference", |
| "data_studies": "Moussa 2016,O'Shea 2015,Singh 2009,Tao 2019", |
| "gt conclusion": "not significant" |
| }, |
| { |
| "group num": "1.2", |
| "outcome": "Number of intubation attempts. Details: Number of laryngoscope blade insertion-and-removal cycles required for intubation; each insertion/removal counts as one attempt, regardless of success.", |
| "study arm": "Videolaryngoscopy (VDL) versus conventional direct laryngoscopy (CDL). Details: Intervention: videolaryngoscopy for neonatal endotracheal intubation using any neonatal video device (e.g., C-MAC, AirTraq, GlideScope/GlideScope cobalt, Truview, or modified Miller videolaryngoscope; including video-assisted teaching/coaching approaches where the instructor can share the airway view). Control: conventional direct laryngoscopy with a standard direct laryngoscope (e.g., Miller/standard neonatal laryngoscope, or video device screen covered so intubation proceeds as direct laryngoscopy).", |
| "Subgroup": "", |
| "Data type": "Continuous", |
| "Effect measure": "Mean Difference", |
| "data_studies": "Moussa 2016,O'Shea 2015,Salama 2019,Tao 2019", |
| "gt conclusion": "not significant" |
| }, |
| { |
| "group num": "1.3", |
| "outcome": "Success rate at first attempt. Details: Proportion of intubations successfully completed on the first intubation attempt.", |
| "study arm": "Videolaryngoscopy (VDL) versus conventional direct laryngoscopy (CDL). Details: Intervention: videolaryngoscopy for neonatal endotracheal intubation using any neonatal video device (e.g., C-MAC, AirTraq, GlideScope/GlideScope cobalt, Truview, or modified Miller videolaryngoscope; including video-assisted teaching/coaching approaches where the instructor can share the airway view). Control: conventional direct laryngoscopy with a standard direct laryngoscope (e.g., Miller/standard neonatal laryngoscope, or video device screen covered so intubation proceeds as direct laryngoscopy).", |
| "Subgroup": "", |
| "Data type": "Dichotomous", |
| "Effect measure": "Risk Ratio", |
| "data_studies": "Moussa 2016,O'Shea 2015,Salama 2019,Singh 2009,Tao 2019,Volz 2018", |
| "gt conclusion": "favor Intervention" |
| }, |
| { |
| "group num": "1.4", |
| "outcome": "Non-airway-related adverse effects: desaturation or bradycardia episodes, or both. Details: Incidence of desaturation episodes (oxygen saturation <95%) OR bradycardia episodes (heart rate <100 beats/min), or both, during intubation.", |
| "study arm": "Videolaryngoscopy (VDL) versus conventional direct laryngoscopy (CDL). Details: Intervention: videolaryngoscopy for neonatal endotracheal intubation using any neonatal video device (e.g., C-MAC, AirTraq, GlideScope/GlideScope cobalt, Truview, or modified Miller videolaryngoscope; including video-assisted teaching/coaching approaches where the instructor can share the airway view). Control: conventional direct laryngoscopy with a standard direct laryngoscope (e.g., Miller/standard neonatal laryngoscope, or video device screen covered so intubation proceeds as direct laryngoscopy).", |
| "Subgroup": "", |
| "Data type": "Dichotomous", |
| "Effect measure": "Risk Ratio", |
| "data_studies": "Moussa 2016,Salama 2019,Tao 2019", |
| "gt conclusion": "not significant" |
| }, |
| { |
| "group num": "1.5", |
| "outcome": "Non-airway-related adverse effects: lowest saturations during intubation. Details: Lowest recorded oxygen saturation (%) from the start of tracheal intubation until normalization of saturation (oxygen saturation >95%).", |
| "study arm": "Videolaryngoscopy (VDL) versus conventional direct laryngoscopy (CDL). Details: Intervention: videolaryngoscopy for neonatal endotracheal intubation using any neonatal video device (e.g., C-MAC, AirTraq, GlideScope/GlideScope cobalt, Truview, or modified Miller videolaryngoscope; including video-assisted teaching/coaching approaches where the instructor can share the airway view). Control: conventional direct laryngoscopy with a standard direct laryngoscope (e.g., Miller/standard neonatal laryngoscope, or video device screen covered so intubation proceeds as direct laryngoscopy).", |
| "Subgroup": "", |
| "Data type": "Continuous", |
| "Effect measure": "Mean Difference", |
| "data_studies": "Moussa 2016,O'Shea 2015", |
| "gt conclusion": "not significant" |
| }, |
| { |
| "group num": "1.6", |
| "outcome": "Airway-related adverse effects: airway trauma. Details: Incidence of airway trauma to oral, pharyngeal, or laryngeal structures, including lacerations or perforations, assessed visually or by laryngoscopic examination.", |
| "study arm": "Videolaryngoscopy (VDL) versus conventional direct laryngoscopy (CDL). Details: Intervention: videolaryngoscopy for neonatal endotracheal intubation using any neonatal video device (e.g., C-MAC, AirTraq, GlideScope/GlideScope cobalt, Truview, or modified Miller videolaryngoscope; including video-assisted teaching/coaching approaches where the instructor can share the airway view). Control: conventional direct laryngoscopy with a standard direct laryngoscope (e.g., Miller/standard neonatal laryngoscope, or video device screen covered so intubation proceeds as direct laryngoscopy).", |
| "Subgroup": "", |
| "Data type": "Dichotomous", |
| "Effect measure": "Risk Ratio", |
| "data_studies": "Moussa 2016,Salama 2019,Singh 2009", |
| "gt conclusion": "favor comparison" |
| } |
| ], |
| "Moussa 2016": [ |
| { |
| "group num": "1.1", |
| "Analysis group": "1", |
| "Analysis number": "1", |
| "Subgroup": "", |
| "Experimental mean": "67.85", |
| "Experimental SD": "35.59", |
| "Experimental cases": "", |
| "Experimental N": "60", |
| "Control mean": "55.04", |
| "Control SD": "45.63", |
| "Control cases": "", |
| "Control N": "47", |
| "Mean": "12.81", |
| "CI start": "-3.041582", |
| "CI end": "28.661582" |
| }, |
| { |
| "group num": "1.2", |
| "Analysis group": "1", |
| "Analysis number": "2", |
| "Subgroup": "", |
| "Experimental mean": "1.38", |
| "Experimental SD": "0.55", |
| "Experimental cases": "", |
| "Experimental N": "109", |
| "Control mean": "1.33", |
| "Control SD": "0.53", |
| "Control cases": "", |
| "Control N": "112", |
| "Mean": "0.05", |
| "CI start": "-0.092462", |
| "CI end": "0.192462" |
| }, |
| { |
| "group num": "1.3", |
| "Analysis group": "1", |
| "Analysis number": "3", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "57", |
| "Experimental N": "101", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "51", |
| "Control N": "112", |
| "Mean": "1.239371", |
| "CI start": "0.950568", |
| "CI end": "1.615918" |
| }, |
| { |
| "group num": "1.4", |
| "Analysis group": "1", |
| "Analysis number": "4", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "6", |
| "Experimental N": "101", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "2", |
| "Control N": "112", |
| "Mean": "3.326733", |
| "CI start": "0.68691", |
| "CI end": "16.111493" |
| }, |
| { |
| "group num": "1.5", |
| "Analysis group": "1", |
| "Analysis number": "5", |
| "Subgroup": "", |
| "Experimental mean": "45.0", |
| "Experimental SD": "25.0", |
| "Experimental cases": "", |
| "Experimental N": "71", |
| "Control mean": "48.0", |
| "Control SD": "25.0", |
| "Control cases": "", |
| "Control N": "82", |
| "Mean": "-3.0", |
| "CI start": "-10.943241", |
| "CI end": "4.943241" |
| }, |
| { |
| "group num": "1.6", |
| "Analysis group": "1", |
| "Analysis number": "6", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "0", |
| "Experimental N": "101", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "5", |
| "Control N": "112", |
| "Mean": "0.100713", |
| "CI start": "0.005639", |
| "CI end": "1.798901" |
| }, |
| { |
| "RoB": "1.0", |
| "Domain1：Random sequence generation (selection bias)": "Low", |
| "Domain2：Allocation concealment (selection bias)": "Low", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes": "High", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes": "Low", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes": "Low", |
| "Domain6：Selective reporting (reporting bias)": "Low", |
| "Domain1：Random sequence generation (selection bias) Support for judgement": "Table of random numbers stratified by year of residency training", |
| "Domain2：Allocation concealment (selection bias) Support for judgement": "Sealed envelopes with the allocation group", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes Support for judgement": "Study could not be blinded.", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes Support for judgement": "Change in color of the carbon dioxide detector, vapor mist in the endotracheal tube, thoracic expansion, assessment of bilateral lung air entry, absence of air entry in the stomach by auscultation, and improvement of clinical parameters were used as objective criteria to assess intubation success.", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes Support for judgement": "34 out of 37 enrolled residents completed the study; outcomes were reported for 34 residents.", |
| "Domain6：Selective reporting (reporting bias) Support for judgement": "Investigators reported all outcomes that were specified in the protocol." |
| } |
| ], |
| "O'Shea 2015": [ |
| { |
| "group num": "1.1", |
| "Analysis group": "1", |
| "Analysis number": "1", |
| "Subgroup": "", |
| "Experimental mean": "54.78", |
| "Experimental SD": "25.04", |
| "Experimental cases": "", |
| "Experimental N": "104", |
| "Control mean": "57.54", |
| "Control SD": "20.98", |
| "Control cases": "", |
| "Control N": "100", |
| "Mean": "-2.76", |
| "CI start": "-9.089945", |
| "CI end": "3.569945" |
| }, |
| { |
| "group num": "1.2", |
| "Analysis group": "1", |
| "Analysis number": "2", |
| "Subgroup": "", |
| "Experimental mean": "1.53", |
| "Experimental SD": "0.84", |
| "Experimental cases": "", |
| "Experimental N": "105", |
| "Control mean": "1.93", |
| "Control SD": "1.04", |
| "Control cases": "", |
| "Control N": "101", |
| "Mean": "-0.4", |
| "CI start": "-0.658752", |
| "CI end": "-0.141248" |
| }, |
| { |
| "group num": "1.3", |
| "Analysis group": "1", |
| "Analysis number": "3", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "69", |
| "Experimental N": "104", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "42", |
| "Control N": "102", |
| "Mean": "1.611264", |
| "CI start": "1.230831", |
| "CI end": "2.109283" |
| }, |
| { |
| "group num": "1.5", |
| "Analysis group": "1", |
| "Analysis number": "5", |
| "Subgroup": "", |
| "Experimental mean": "65.12", |
| "Experimental SD": "23.4", |
| "Experimental cases": "", |
| "Experimental N": "105", |
| "Control mean": "64.42", |
| "Control SD": "23.47", |
| "Control cases": "", |
| "Control N": "101", |
| "Mean": "0.7", |
| "CI start": "-5.701834", |
| "CI end": "7.101834" |
| }, |
| { |
| "RoB": "1.0", |
| "Domain1：Random sequence generation (selection bias)": "Low", |
| "Domain2：Allocation concealment (selection bias)": "Low", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes": "High", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes": "Low", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes": "Low", |
| "Domain6：Selective reporting (reporting bias)": "Low", |
| "Domain1：Random sequence generation (selection bias) Support for judgement": "Computer‐generated, variable‐sized, block randomization sequence used", |
| "Domain2：Allocation concealment (selection bias) Support for judgement": "Sequentially numbered, opaque envelopes with randomization cards", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes Support for judgement": "Participant could potentially know if the supervisor had access to the videolaryngoscope screen during their attempt, which could impact their performance.", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes Support for judgement": "Primary outcome was success at the intubation attempt. Endotracheal tube placement was confirmed by a colorimetric exhaled carbon dioxide detector, which is an objective criterion to assess intubation success.", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes Support for judgement": "After randomization, only 7 neonates were excluded (3 in the intervention group and 4 in the control group); analysis on an intention‐to‐treat basis", |
| "Domain6：Selective reporting (reporting bias) Support for judgement": "Investigators reported all outcomes that were specified in the protocol." |
| } |
| ], |
| "Salama 2019": [ |
| { |
| "group num": "1.2", |
| "Analysis group": "1", |
| "Analysis number": "2", |
| "Subgroup": "", |
| "Experimental mean": "1.1", |
| "Experimental SD": "0.3051286", |
| "Experimental cases": "", |
| "Experimental N": "30", |
| "Control mean": "1.233333", |
| "Control SD": "0.5040069", |
| "Control cases": "", |
| "Control N": "30", |
| "Mean": "-0.133333", |
| "CI start": "-0.344162", |
| "CI end": "0.077496" |
| }, |
| { |
| "group num": "1.3", |
| "Analysis group": "1", |
| "Analysis number": "3", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "27", |
| "Experimental N": "30", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "24", |
| "Control N": "30", |
| "Mean": "1.125", |
| "CI start": "0.907328", |
| "CI end": "1.394893" |
| }, |
| { |
| "group num": "1.4", |
| "Analysis group": "1", |
| "Analysis number": "4", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "2", |
| "Experimental N": "30", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "2", |
| "Control N": "30", |
| "Mean": "1.0", |
| "CI start": "0.150543", |
| "CI end": "6.642611" |
| }, |
| { |
| "group num": "1.6", |
| "Analysis group": "1", |
| "Analysis number": "6", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "1", |
| "Experimental N": "30", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "4", |
| "Control N": "30", |
| "Mean": "0.25", |
| "CI start": "0.029648", |
| "CI end": "2.108078" |
| }, |
| { |
| "RoB": "1.0", |
| "Domain1：Random sequence generation (selection bias)": "Low", |
| "Domain2：Allocation concealment (selection bias)": "Low", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes": "High", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes": "Low", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes": "Low", |
| "Domain6：Selective reporting (reporting bias)": "Low", |
| "Domain1：Random sequence generation (selection bias) Support for judgement": "Randomization was performed by an independent statistician in a 1:1 ratio.", |
| "Domain2：Allocation concealment (selection bias) Support for judgement": "Allocation concealment was done by sequentially numbered, sealed, opaque envelopes.", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes Support for judgement": "Participants could not be blinded.", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes Support for judgement": "Except for the percentage of glottic opening score, all data were recorded by an independent observer not involved in the study.", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes Support for judgement": "All participants randomised to each group were included in the outcomes.", |
| "Domain6：Selective reporting (reporting bias) Support for judgement": "Investigators reported all outcomes that were specified in the protocol." |
| } |
| ], |
| "Singh 2009": [ |
| { |
| "group num": "1.1", |
| "Analysis group": "1", |
| "Analysis number": "1", |
| "Subgroup": "", |
| "Experimental mean": "18.18", |
| "Experimental SD": "2.72", |
| "Experimental cases": "", |
| "Experimental N": "30", |
| "Control mean": "16.3", |
| "Control SD": "1.43", |
| "Control cases": "", |
| "Control N": "30", |
| "Mean": "1.88", |
| "CI start": "0.780363", |
| "CI end": "2.979637" |
| }, |
| { |
| "group num": "1.3", |
| "Analysis group": "1", |
| "Analysis number": "3", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "28", |
| "Experimental N": "30", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "27", |
| "Control N": "30", |
| "Mean": "1.037037", |
| "CI start": "0.890014", |
| "CI end": "1.208347" |
| }, |
| { |
| "group num": "1.6", |
| "Analysis group": "1", |
| "Analysis number": "6", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "0", |
| "Experimental N": "30", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "1", |
| "Control N": "30", |
| "Mean": "0.333333", |
| "CI start": "0.014119", |
| "CI end": "7.869869" |
| }, |
| { |
| "RoB": "1.0", |
| "Domain1：Random sequence generation (selection bias)": "Low", |
| "Domain2：Allocation concealment (selection bias)": "Unclear", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes": "High", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes": "Low", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes": "Low", |
| "Domain6：Selective reporting (reporting bias)": "Low", |
| "Domain1：Random sequence generation (selection bias) Support for judgement": "Randomization done by chit in a box technique.", |
| "Domain2：Allocation concealment (selection bias) Support for judgement": "No details given.", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes Support for judgement": "Participants could not be blinded.", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes Support for judgement": "Time to intubation and intubation attempts were measured using objective criteria.", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes Support for judgement": "All participants randomised to each group were included in the outcomes.", |
| "Domain6：Selective reporting (reporting bias) Support for judgement": "Investigators reported all outcomes that were specified in the protocol." |
| } |
| ], |
| "Tao 2019": [ |
| { |
| "group num": "1.1", |
| "Analysis group": "1", |
| "Analysis number": "1", |
| "Subgroup": "", |
| "Experimental mean": "33.09", |
| "Experimental SD": "16.53", |
| "Experimental cases": "", |
| "Experimental N": "35", |
| "Control mean": "31.63", |
| "Control SD": "5.71", |
| "Control cases": "", |
| "Control N": "35", |
| "Mean": "1.46", |
| "CI start": "-4.333817", |
| "CI end": "7.253817" |
| }, |
| { |
| "group num": "1.2", |
| "Analysis group": "1", |
| "Analysis number": "2", |
| "Subgroup": "", |
| "Experimental mean": "1.028571", |
| "Experimental SD": "0.1690309", |
| "Experimental cases": "", |
| "Experimental N": "35", |
| "Control mean": "1.171429", |
| "Control SD": "0.4528157", |
| "Control cases": "", |
| "Control N": "35", |
| "Mean": "-0.142858", |
| "CI start": "-0.302984", |
| "CI end": "0.017268" |
| }, |
| { |
| "group num": "1.3", |
| "Analysis group": "1", |
| "Analysis number": "3", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "34", |
| "Experimental N": "35", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "30", |
| "Control N": "35", |
| "Mean": "1.133333", |
| "CI start": "0.978694", |
| "CI end": "1.312407" |
| }, |
| { |
| "group num": "1.4", |
| "Analysis group": "1", |
| "Analysis number": "4", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "0", |
| "Experimental N": "35", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "5", |
| "Control N": "35", |
| "Mean": "0.090909", |
| "CI start": "0.005217", |
| "CI end": "1.584181" |
| }, |
| { |
| "RoB": "1.0", |
| "Domain1：Random sequence generation (selection bias)": "Low", |
| "Domain2：Allocation concealment (selection bias)": "Low", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes": "High", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes": "Low", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes": "Low", |
| "Domain6：Selective reporting (reporting bias)": "Low", |
| "Domain1：Random sequence generation (selection bias) Support for judgement": "Stratified blocked randomization", |
| "Domain2：Allocation concealment (selection bias) Support for judgement": "An envelope containing the allocation information was given to the anesthesiologist who performed the intubation, and the anesthesiologist opened the envelope immediately before induction of anesthesia.", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes Support for judgement": "Participants could not be blinded.", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes Support for judgement": "An observer, who was blinded to neonate group assignment, was responsible for recording the time to intubation.", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes Support for judgement": "All participants randomised to each group were included in the outcomes.", |
| "Domain6：Selective reporting (reporting bias) Support for judgement": "Investigators reported all outcomes that were specified in the protocol." |
| } |
| ], |
| "Volz 2018": [ |
| { |
| "group num": "1.3", |
| "Analysis group": "1", |
| "Analysis number": "3", |
| "Subgroup": "", |
| "Experimental mean": "", |
| "Experimental SD": "", |
| "Experimental cases": "14", |
| "Experimental N": "24", |
| "Control mean": "", |
| "Control SD": "", |
| "Control cases": "8", |
| "Control N": "24", |
| "Mean": "1.75", |
| "CI start": "0.905278", |
| "CI end": "3.382938" |
| }, |
| { |
| "RoB": "1.0", |
| "Domain1：Random sequence generation (selection bias)": "Low", |
| "Domain2：Allocation concealment (selection bias)": "Unclear", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes": "High", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes": "Low", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes": "Low", |
| "Domain6：Selective reporting (reporting bias)": "Low", |
| "Domain1：Random sequence generation (selection bias) Support for judgement": "Residents were randomised by pulling concealed names out of a box using a 1:1 randomization scheme.", |
| "Domain2：Allocation concealment (selection bias) Support for judgement": "No details given", |
| "Domain3：Blinding of participants and personnel (performance bias) All outcomes Support for judgement": "Participants were not blinded to their assigned groups.", |
| "Domain4：Blinding of outcome assessment (detection bias) All outcomes Support for judgement": "Investigators who performed data analysis were blinded to the participants’ assigned study groups.", |
| "Domain5：Incomplete outcome data (attrition bias) All outcomes Support for judgement": "No participants were excluded.", |
| "Domain6：Selective reporting (reporting bias) Support for judgement": "Investigators reported all outcomes that were specified in the protocol." |
| } |
| ], |
| "date": "2022/12" |
| } |
|
|
