Unnamed: 0,Gene symbol,Ranking,Annotation & reasoning,Additional note,Gene Symbol 0,NeuN,1-50,Pan Neuron marker often used for ISH,,NeuN 1,SST,1-50,Defines SST+ Interneurons,,SST 2,PVALB,1-50,Identifies inhibitory interneurons,,PVALB 3,CLND5,1-50,Endothelial cells / Mural cells,,CLND5 4,HBA1,1-50,Endothelial cells / Mural cells,,HBA1 5,ASCA2,1-50,Astrocyte marker often used for Bead collection,,ASCA2 6,GFAP,1-50,Astrocyte marker ,,GFAP 7,CX3CR1 ,1-50,Microglia marker,,CX3CR1 8,TMEM119,1-50,Microglial marker,,TMEM119 9,AIF1,1-50,IBA1 is often used for in situ hybridzation to label microglial cells. ,,AIF1 10,OLIG2,1-50,"Expressed by OPCs, getting cells ready for differentiation into myelin-forming oligodendocytes. ",,OLIG2 11,CD22,1-50,Expressed by oligodendrocytes in huamns and binds to sialic acid-dependent ligands on microglia. ,,CD22 12,Th,1-50,Often used by ISH of dopaminergic neurons. ,,Th 13,Reln,1-50,"Genes that seperate layers of cortical region (Huuki-Myers, BioRxiv, 2023)",,Reln 14,Aqp4,1-50,"Genes that seperate layers of cortical region (Huuki-Myers, BioRxiv, 2023)",,Aqp4 15,SPARC,1-50,"Genes that seperate layers of cortical region (Huuki-Myers, BioRxiv, 2023)",,SPARC 16,HTRA1,1-50,"Genes that seperate layers of cortical region (Huuki-Myers, BioRxiv, 2023)",,HTRA1 17,VIP,1-50,Labels interneurons in PFC that signal and inhibits SST+ interneurons,,VIP 18,Fos,1-50,Activation-related genes from neurons. ,,Fos 19,Arc,1-50,Activation-related genes from neurons. ,,Arc 20,Egr1,1-50,Activation-related genes from neurons. ,,Egr1 21,BDNF,1-50,"For survival mechanisms of neuronal homeostasis, often associated with disease. ",,BDNF 22,ADORA1,1-50,Neurotransmitter receptors,,ADORA1 23,HTR1A,1-50,Neurotransmitter receptors,,HTR1A 24,HTR2A,1-50,Neurotransmitter receptors,,HTR2A 25,HTR3A,1-50,Neurotransmitter receptors,,HTR3A 26,HTR4,1-50,Neurotransmitter receptors,,HTR4 27,DRD1,1-50,Neurotransmitter receptors,,DRD1 28,DRD2,1-50,Neurotransmitter receptors,,DRD2 29,DRD4,1-50,Neurotransmitter receptors,,DRD4 30,NR3C1,1-50,Neurotransmitter receptors,,NR3C1 31,NPY1R,1-50,Neurotransmitter receptors,,NPY1R 32,OXTR,1-50,Expressed by SST+ neurons to respond to ,,OXTR 33,GRIN2B,1-50,Receptors common for neural plasticity,,GRIN2B 34,GABRA1,1-50,Receptors common for neural plasticity,,GABRA1 35,GRIA1,1-50,Receptors common for neural plasticity,,GRIA1 36,NEDD4,1-50,Marker for excitatory neurons,,NEDD4 37,FBXO2,1-50,Marker for excitatory neurons,,FBXO2 38,mTOR,1-50,Marker for excitatory neurons,,mTOR 39,DDIT4,1-50,Marker for excitatory neurons,,DDIT4 40,TH,1-50,Marker for excitatory neurons,,TH 41,PDGFRA,1-50,OPCs,,PDGFRA 42,GAD1,1-50,"Glutamate Decarboxylase 1, catalyzing production from L-glut. ",,GAD1 43,CHAT,1-50,Neuron enzyme for ACh,,CHAT 44,GRIN2A,1-50,NMDA receptors,,GRIN2A 45,GABRD,1-50,GABA receptors,,GABRD 46,GABRA1,1-50,GABA receptors,,GABRA1 47,TREM2,1-50,microglial marker,,TREM2 48,CSF1R,1-50,microglial marker,,CSF1R 49,IL10,1-50,Microglia function,,IL10 50,EFNA5,50-100,Important pathways for neural plasticity and synaptic homeostasis. ,,EFNA5 51,EPHA5,50-100,Important pathways for neural plasticity and synaptic homeostasis. ,,EPHA5 52,FYN,50-100,Important pathways for neural plasticity and synaptic homeostasis. ,,FYN 53,CARMN,50-100,Endothelial cells: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,CARMN 54,ITIH5,50-100,Endothelial cells: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,ITIH5 55,MECOM,50-100,Endothelial cells: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,MECOM 56,EBF1,50-100,Endothelial cells: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,EBF1 57,VWF,50-100,Endothelial cells: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,VWF 58,LINC02712,50-100,Microglia: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,LINC02712 59,ITGAX,50-100,Microglia: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,ITGAX 60,BLNK,50-100,Microglia: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,BLNK 61,CSF2RA,50-100,Microglia: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,CSF2RA 62,FOLH1,50-100,Oligodendrocytes: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,FOLH1 63,LINC01608,50-100,Oligodendrocytes: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,LINC01608 64,SLC5A11,50-100,Oligodendrocytes: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,SLC5A11 65,OPC,50-100,OPC: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,OPC 66,AC004852.2,50-100,OPC: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,AC004852.2 67,FERMT1,50-100,OPC: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,FERMT1 68,COL9A1,50-100,OPC: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,COL9A1 69,STK32A,50-100,OPC: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,STK32A 70,FGF13,50-100,Excitatory Layer 2 or 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,FGF13 71,SLC12A8,50-100,Excitatory Layer 2 or 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,SLC12A8 72,DCBLD2,50-100,Excitatory Layer 2 or 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,DCBLD2 73,MPC1,50-100,Excitatory Layer 2 or 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,MPC1 74,LINC02296,50-100,Excitatory Layer 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,LINC02296 75,AC008674.1,50-100,Excitatory Layer 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,AC008674.1 76,CLRA3,50-100,Excitatory Layer 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,CLRA3 77,CPHR1,50-100,Excitatory Layer 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,CPHR1 78,FBXL16,50-100,Excitatory Layer 3/4/5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,FBXL16 79,MAP1A,50-100,Excitatory Layer 3/4/5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,MAP1A 80,UBB,50-100,Excitatory Layer 3/4/5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,UBB 81,ENC1,50-100,Excitatory Layer 3/4/5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,ENC1 82,TSHZ2,50-100,Excitatory Layer 4 Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,TSHZ2 83,VGF,50-100,Excitatory Layer 4 Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,VGF 84,UBE2E3,50-100,Excitatory Layer 4 Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,UBE2E3 85,APP003066.1,50-100,Excitatory Layer 5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,APP003066.1 86,COL12A1,50-100,Excitatory Layer 5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,COL12A1 87,TRABD2A,50-100,Excitatory Layer 5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,TRABD2A 88,TLL1,50-100,Excitatory Layer 5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,TLL1 89,LINC00343,50-100,Excitatory L5/6,,LINC00343 90,THEMIS,50-100,Excitatory L5/6,,THEMIS 91,AC015943.1,50-100,Excitatory L5/6,,AC015943.1 92,LINC02718,50-100,Excitatory L6: Top genes from Huuki-Myers,,LINC02718 93,MCTP2,50-100,Excitatory L6: Top genes from Huuki-Myers,,MCTP2 94,AC006299.1,50-100,Excitatory L6: Top genes from Huuki-Myers,,AC006299.1 95,DPP4,50-100,Excitatory L6: Top genes from Huuki-Myers,,DPP4 96,MYO3B,50-100,Inhibitory neurons: Top genes from Huuki-Myers,,MYO3B 97,SLC27A6,50-100,Inhibitory neurons: Top genes from Huuki-Myers,,SLC27A6 98,MINAR1,50-100,Inhibitory neurons: Top genes from Huuki-Myers,,MINAR1 99,BTBD11,50-100,Inhibitory neurons: Top genes from Huuki-Myers,,BTBD11 100,FBN2,100-150,Inhibitory neurons: Top genes from Huuki-Myers,,FBN2 101,GRIP2,100-150,Inhibitory neurons: Top genes from Huuki-Myers,,GRIP2 102,COMT,100-150,Enzymes that degrade neurotransmitters,,COMT 103,SLC6A3,100-150,Dopamine transporter,,SLC6A3 104,MAOA,100-150,Breakdown of neurotransmitters,,MAOA 105,CREB1,100-150,Neural activation related genes,,CREB1 106,FOS,100-150,Neural activation related genes,,FOS 107,JUNB,100-150,Neural activation related genes,,JUNB 108,NFAT1,100-150,Neural activation related genes,,NFAT1 109,CRTC1,100-150,Neural activation related genes,,CRTC1 110,CAMK2A,100-150,Neural activation related genes,,CAMK2A 111,CAMK1D,100-150,Neural activation related genes,,CAMK1D 112,APOE4,100-150,"Alzhiemers, microglia. ",,APOE4 113,SHANK3,100-150,Genes altered in ASD,,SHANK3 114,RAC1,100-150,Genes altered in ASD,,RAC1 115,PAK,100-150,Genes altered in ASD,,PAK 116,COFILIN,100-150,Genes altered in ASD,,COFILIN 117,NR2A,100-150,Genes altered in Schizophernia,,NR2A 118,GAD67,100-150,Genes altered in Schizophernia,,GAD67 119,CALM2,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,CALM2 120,SYN1,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,SYN1 121,RAB3A,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,RAB3A 122,RAB4B,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,RAB4B 123,TUBB4,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,TUBB4 124,NR2B,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,NR2B 125,PSD96,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,PSD96 126,cpg15,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,cpg15 127,NTRK2,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,NTRK2 128,HLA-A,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,HLA-A 129,PLK2,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,PLK2 130,Homer1,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,Homer1 131,Arc,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,Arc 132,MIR134,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,MIR134 133,Mecp2,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,Mecp2 134,MEF22c,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,MEF22c 135,CARF,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,CARF 136,HLA-B,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,HLA-B 137,HLA-C,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,HLA-C 138,KIT,100-150,Inhibitory neurons: Top genes from Huuki-Myers,,KIT 139,PLXDC2,100-150,Top DEG from Jupyter of microglia,,PLXDC2 140,DOCK4,100-150,Top DEG from Jupyter of microglia,,DOCK4 141,DOCK8,100-150,Top DEG from Jupyter of microglia,,DOCK8 142,AdGRV1,100-150,Top DEG from jupyter of astrocytes,,AdGRV1 143,SLC1A2,100-150,Top DEG from jupyter of astrocytes,,SLC1A2 144,MSI2,100-150,Top DEG from jupyter of astrocytes,,MSI2 145,GPC5,100-150,Top DEG from jupyter of astrocytes,,GPC5 146,SORCS3,100-150,Caudal Ganglionic derived GABAergic cortical interneurons from Top DEG from Jupyter,,SORCS3 147,ADARB2,100-150,Caudal Ganglionic derived GABAergic cortical interneurons from Top DEG from Jupyter,,ADARB2 148,CXCL14,100-150,Caudal Ganglionic derived GABAergic cortical interneurons from Top DEG from Jupyter,,CXCL14 149,SLC35F4,100-150,Caudal Ganglionic derived GABAergic cortical interneurons from Top DEG from Jupyter,,SLC35F4