Unnamed: 0,Gene symbol,Ranking,Annotation & reasoning,Additional note,Data Source,Gene Symbol
0,TCL1A,1-50,B cell,,"""Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn’s disease"", CD samples collected from terminal ileum (TI) and ascending colon (AC) through endoscopy and surgical",TCL1A
1,MS4A1,1-50,B cell,,,MS4A1
2,CD79A,1-50,B cell,,,CD79A
3,BLK,50-100,B cell,,,BLK
4,FCRL1,50-100,B cell,,,FCRL1
5,PAX5,50-100,B cell,,,PAX5
6,TNFRSF13C,50-100,B cell,,,TNFRSF13C
7,CNR2,50-100,B cell,,,CNR2
8,CD22,50-100,B cell,Mast,,CD22
11,BEST4,1-50,BEST4,Canonical marker,,BEST4
12,CA7,1-50,BEST4,Canonical marker,,CA7
13,OTOP2,1-50,BEST4,Canonical marker,,OTOP2
14,CA4,50-100,BEST4,Co-exp with CA7,,CA4
15,NBPF19,50-100,BEST4,,,NBPF19
16,NBPF14,50-100,BEST4,,,NBPF14
20,AQP8,1-50,Clonocyte,,,AQP8
21,CEACAM1,1-50,Clonocyte,,,CEACAM1
22,AQP8,1-50,Colonocyte,,,AQP8
23,CA2,50-100,Colonocyte,Multiple cell types,,CA2
24,CA1,50-100,Colonocyte,,,CA1
25,HMGCS2,50-100,Colonocyte,Multiple cell types,,HMGCS2
26,CD24,50-100,Colonocyte,Multiple cell types,,CD24
31,TOP2A,1-50,Cycling,,,TOP2A
32,MKI67,1-50,Cycling,,,MKI67
33,HMGB2,50-100,Cycling,,,HMGB2
34,OLFM4,1-50,Cycling/Stem,,,OLFM4
35,CENPF,50-100,Cycling/Stem,,,CENPF
36,PRC1,50-100,Cycling/Stem,,,PRC1
37,CCNB2,50-100,Cycling/Stem,,,CCNB2
41,CHGB,1-50,EEC,,,CHGB
42,CHGA,1-50,EEC,,,CHGA
43,PCSK1N,50-100,EEC,,,PCSK1N
44,KCNB2,50-100,EEC,,,KCNB2
45,NEUROD1,50-100,EEC,,,NEUROD1
49,ACKR1,1-50,Endo,Vein,,ACKR1
50,VWF,1-50,Endo,Cannonical endo marker,,VWF
51,PECAM1,1-50,Endo,Canonical marker,,PECAM1
52,CLDN5,50-100,Endo,,,CLDN5
53,SOX18,50-100,Endo,,,SOX18
54,RAMP3,50-100,Endo,,,RAMP3
55,RAMP2,50-100,Endo,,,RAMP2
58,APOB,1-50,Enterocyte,Multiple cell types,,APOB
59,APOA4,1-50,Enterocyte,Multiple cell types,,APOA4
60,APOA1,1-50,Enterocyte,,,APOA1
61,SLC15A1,50-100,Enterocyte,,,SLC15A1
62,SLC6A19,50-100,Enterocyte,,,SLC6A19
68,FABP1,1-50,Epi,Multiple cell types,,FABP1
69,COL1A2,1-50,Fibro,"Canonical marker, high expression",,COL1A2
70,COL1A1,1-50,Fibro,"Canonical marker, high expression",,COL1A1
71,DCN,1-50,Fibro,"Canonical marker, high expression",,DCN
72,COL3A1,50-100,Fibro,,,COL3A1
73,PDGFRA,50-100,Fibro,,,PDGFRA
74,MFAP4,50-100,Fibro,,,MFAP4
75,SFRP2,50-100,Fibro,,,SFRP2
77,TFF3,1-50,Goblet,"Canonical marker, high expression",,TFF3
78,MUC2,1-50,Goblet,"Canonical marker, high expression",,MUC2
79,SPINK4,1-50,Goblet,,,SPINK4
80,ITLN1,50-100,Goblet,,,ITLN1
81,CLCA1,50-100,Goblet,,,CLCA1
82,FCGBP,50-100,Goblet,,,FCGBP
84,DUOX2,1-50,LND,Important cell state in disease,,DUOX2
85,LCN2,1-50,LND,Important cell state in disease,,LCN2
86,DMBT1,1-50,LND,Important cell state in disease,,DMBT1
87,REG1A,1-50,LND,Important cell state in disease,,REG1A
88,SAA1,50-100,LND,,,SAA1
89,NOS2,50-100,LND,,,NOS2
93,CPA3,1-50,Mast,,,CPA3
94,KIT,1-50,Mast,,,KIT
95,CTSG,50-100,Mast,,,CTSG
96,GATA2,50-100,Mast,,,GATA2
97,TPSAB1,50-100,Mast,,,TPSAB1
98,TPSB2,50-100,Mast,,,TPSB2
101,C1QA,1-50,Myel,"Canonical myeloid marker, too high expression",,C1QA
102,C1QB,1-50,Myel,Canonical myeloid marker,,C1QB
103,C1QC,50-100,Myel,Canonical myeloid marker; co-express with C1QA and C1QB,,C1QC
104,CSF3R,50-100,Myel,,,CSF3R
111,S100A8,1-50,Neutrophils,,,S100A8
112,S100A9,1-50,Neutrophils,,,S100A9
113,NKG7,1-50,NK,,,NKG7
114,DEFA6,1-50,Paneth,,,DEFA6
115,DEFA5,50-100,Paneth,,,DEFA5
119,IGHA1,1-50,PCs,,,IGHA1
120,JCHAIN,1-50,PCs,,,JCHAIN
121,IGHA2,1-50,PCs,,,IGHA2
122,IGKC,50-100,PCs,"Canonical marker, multiple cell types, too high expression",,IGKC
123,CCR10,50-100,PCs,,,CCR10
124,MZB1,50-100,PCs,,,MZB1
129,LGR5,1-50,Stem,,,LGR5
130,CD3D,1-50,T,,,CD3D
131,CD8A,1-50,T,,,CD8A
132,TRAC,1-50,T,,,TRAC
133,FOXP3,1-50,T,Tregs,,FOXP3
134,CTLA4,1-50,T,,,CTLA4
135,GZMB,1-50,T,T-cyto,,GZMB
136,CD4,50-100,T,,,CD4
137,CCL5,50-100,T,,,CCL5
138,CD3E,50-100,T,,,CD3E
143,LRMP,1-50,Tuft,,,LRMP
144,POU2F3,50-100,Tuft,,,POU2F3
145,HPGDS,50-100,Tuft,,,HPGDS