Unnamed: 0,gene_name,annotation,top_50,top_100,top_150,Gene Symbol
0,ADGRV1,DE in astrocyte in reference dataset,1,1,1,ADGRV1
1,SLC1A3,astrocyte marker literature,1,1,1,SLC1A3
2,SLC1A2,astrocyte marker literature,1,1,1,SLC1A2
3,CDH20,"DE in Oligo, OPC, astrocyte in reference dataset",1,1,1,CDH20
4,PTPRZ1,DE in OPC and astrocytesin reference dataset,1,1,1,PTPRZ1
5,ST18,DE in Oligodendrocyte in reference dataset,1,1,1,ST18
6,MBP,Oligodendrocyte marker / gene linked with methylation,1,1,1,MBP
7,PTGDS,oligodendrocyte subtype marker in literature,1,1,1,PTGDS
8,SST,marker of sstGABAergic cortinal interneuron,1,1,1,SST
9,GAD1,GABAergin neuronal maker,1,1,1,GAD1
10,GAD2,GABAergin neuronal maker,1,1,1,GAD2
11,ADARB2,GABAergic neurons marker,1,1,1,ADARB2
12,SOX6,"DE in reference dataset: sstGABAnergic, pvalb GABAnergic neurons, OPC, astrocyte DE",1,1,1,SOX6
13,SATB2,glutaminergic neuronal marker + DE in dataset,1,1,1,SATB2
14,HS3ST4,glutaminergic neuronal marker + DE in dataset,1,1,1,HS3ST4
15,TSHZ2,cortical neuron marker,1,1,1,TSHZ2
16,RTN1,broad neuronal marker,1,1,1,RTN1
17,NFIB,marker of several GABAergic neurons,1,1,1,NFIB
18,MAP2,mature neuronal marker,1,1,1,MAP2
19,LHFPL3,DE in OPC in reference dataset,1,1,1,LHFPL3
20,DSCAM,DE in OPC and vip-GAB in referece,1,1,1,DSCAM
21,CTNNA3,DE in oligo in reference dataset,1,1,1,CTNNA3
22,EGFR,"GABAergic cortinal interneuron, literature + DE in reference dataset",1,1,1,EGFR
23,NXPH2,Marker of GABAergic + DE in GABAergic cortinal interneuron in reference,1,1,1,NXPH2
24,CUX2,DE expressed in neurons reference dataset,1,1,1,CUX2
25,RXFP1,glutaminergic neuronal marker + DE in dataset,1,1,1,RXFP1
26,KCNIP4,interneuron and OPC + DE in reference dataset,1,1,1,KCNIP4
27,MEF2C,Marker of glutamatergic neurons,1,1,1,MEF2C
28,CHL1,Marker of neuroplasticity/neurotropic,1,1,1,CHL1
29,GRIK4,gene involved in synaptic signaling,1,1,1,GRIK4
30,GRIN2B,gene involved in synaptic signaling,1,1,1,GRIN2B
31,PLP1,genes linked to myelination,1,1,1,PLP1
32,SYT1,genes linked to calcium/calmodulin pathways,1,1,1,SYT1
33,ATP2B2,gene linked to metabolic alteratsion,1,1,1,ATP2B2
34,ATP1B1,gene linked to metabolic alteratsion,1,1,1,ATP1B1
35,SYNDIG1,microglia marker gene in lit + DE in ref data,1,1,1,SYNDIG1
36,HSP90AA1,microglial subtype marker,1,1,1,HSP90AA1
37,ETV5,astrocyte suptype marker,1,1,1,ETV5
38,STMN2,broad neuronal markers,1,1,1,STMN2
39,KCNJ6,Dopaminergic neuron marker,1,1,1,KCNJ6
40,UNC13C,GABAergic neuron marker,1,1,1,UNC13C
41,ITM2B,gene linked to B-amyloid aggregation,1,1,1,ITM2B
42,GRIA1,gene linked to glutamate transport,1,1,1,GRIA1
43,GRIA2,gene linked to glutamate transport,1,1,1,GRIA2
44,CAMK2A,gene linked to neurotransmitter pathways,1,1,1,CAMK2A
45,CALM2,genes linked to calcium/calmodulin pathways,1,1,1,CALM2
46,CAMK4,genes linked to calcium/calmodulin pathways,1,1,1,CAMK4
47,FYN,genes linked to inflammation/immune response,1,1,1,FYN
48,CALM1,genes linked to calcium/calmodulin pathways,1,1,1,CALM1
49,ATP1A1,gene linked to metabolic alteratsion,1,1,1,ATP1A1
50,P2RY12,homeostatic microglial gene,0,1,1,P2RY12
51,P2RY12,activated microglial makers,0,1,1,P2RY12
52,FGFR3,astrocyte marker literature,0,1,1,FGFR3
53,PDGFRA,OPC maker + DE in reference dataset,0,1,1,PDGFRA
54,OPALIN,oligodendrocyte marker in literature + DE in reference dataset,0,1,1,OPALIN
55,MOG,mature oligodendrocyte marker,0,1,1,MOG
56,VIP,marker of vip GABAergic cortinal interneuron,0,1,1,VIP
57,PROX1,GABAergic cortinal interneuron marker + DE,0,1,1,PROX1
58,SULF1,subtypes of glutaminergic neuronal also DE in dataset,0,1,1,SULF1
59,GLUL,astrocyte marker literature,0,1,1,GLUL
60,MERTK,astrocyte suptype marker from lit,0,1,1,MERTK
61,SIRT2,cell cycle genes,0,1,1,SIRT2
62,RGS5,pericyte marker,0,1,1,RGS5
63,LHX6,"GABAergic cortinal interneuron, lit, DE",0,1,1,LHX6
64,SLC17A7,glutamatergic neuron,0,1,1,SLC17A7
65,ATP1A2,gene linked to metabolic alteratsion,0,1,1,ATP1A2
66,BIN1,microglia marker,0,1,1,BIN1
67,NFKB1,inflammatory microglial marker gene,0,1,1,NFKB1
68,HIF1A,microglial subtype marker,0,1,1,HIF1A
69,LAMP1,expressed in some microglia,0,1,1,LAMP1
70,ATP1B2,astrocyte marker literature,0,1,1,ATP1B2
71,HOPX,oligodendrocyte subtype marker in literature,0,1,1,HOPX
72,NEFL,neuronal marker,0,1,1,NEFL
73,APOE,linked to B-amyloid aggregation,0,1,1,APOE
74,CST3,linked to B-amyloid aggregation,0,1,1,CST3
75,SET,gene associated with neuroplasticity/neurotropic,0,1,1,SET
76,PCP4,gene associated with neuroplasticity/neurotropic,0,1,1,PCP4
77,PTPRN,gene associated with cell-cell signaling,0,1,1,PTPRN
78,PIK3CA,gene associated with cell migration,0,1,1,PIK3CA
79,CPLX2,gene associated with synaptic signaling,0,1,1,CPLX2
80,NDUFA4,gene linked to metabolic alteratsion,0,1,1,NDUFA4
81,ATP5F1D,gene linked to metabolic alteratsion,0,1,1,ATP5F1D
82,MDH1,gene linked to metabolic alteratsion,0,1,1,MDH1
83,COX4I1,gene linked to metabolic alteratsion,0,1,1,COX4I1
84,NCAN,gene associated with biosynthesis,0,1,1,NCAN
85,RPL15,gene associated with biosynthesis,0,1,1,RPL15
86,PSMC6,gene associated with proteosome,0,1,1,PSMC6
87,PSMA1,gene associated with proteosome,0,1,1,PSMA1
88,MAPT,mature neuronal marker,0,1,1,MAPT
89,ITM2C,linked to B-amyloid aggregation,0,1,1,ITM2C
90,APBB1,linked to B-amyloid aggregation,0,1,1,APBB1
91,WASL,gene associated with cell migration,0,1,1,WASL
92,ARPC3,gene associated with cell migration,0,1,1,ARPC3
93,SCN1B,gene associated with synaptic signaling,0,1,1,SCN1B
94,PRKCG,gene associated with neurotransmitter pathways,0,1,1,PRKCG
95,NDUFV3,gene linked to metabolic alteratsion,0,1,1,NDUFV3
96,ATP5F1B,gene linked to metabolic alteratsion,0,1,1,ATP5F1B
97,ATP5F1A,gene linked to metabolic alteratsion,0,1,1,ATP5F1A
98,MRPL57,gene associated with biosynthesis,0,1,1,MRPL57
99,EEF1A2,gene associated with biosynthesis,0,1,1,EEF1A2
100,FARSB,gene associated with biosynthesis,0,1,1,FARSB
101,BLNK,microglia DE preivous paper + DE in ref data,0,0,1,BLNK
102,MRC1,"activated microglial makers in literature, DE in reference dataset",0,0,1,MRC1
103,CD14,"microglia marked in literature, DE in reference dataset",0,0,1,CD14
104,CX3CR1,homeostatic microglial gene,0,0,1,CX3CR1
105,CD74,microglia marker,0,0,1,CD74
106,SPI1,microglia marker,0,0,1,SPI1
107,C1QB,microglia marker,0,0,1,C1QB
108,GFAP,"astrocyte marker in literature, DE in reference dataset",0,0,1,GFAP
109,AQP4,"astrocyte marker in literature, DE in reference dataset",0,0,1,AQP4
110,AGT,astrocyte marker literature,0,0,1,AGT
111,GJB6,astrocyte marker literature,0,0,1,GJB6
112,SOX10,oligodendrocyte marker in literature,0,0,1,SOX10
113,OLIG1,oligodendrocyte marker in literature,0,0,1,OLIG1
114,OLIG2,oligodendrocyte marker in literature,0,0,1,OLIG2
115,MAG,Myelinating Oligodendrocyte Markers,0,0,1,MAG
116,KLK6,oligodendrocyte subtype marker in literature,0,0,1,KLK6
117,ASPA,mature oligodendrocyte marker,0,0,1,ASPA
118,ITM2A,endothelial marker lit,0,0,1,ITM2A
119,PCNA,cell cycle genes,0,0,1,PCNA
120,MCM6,cell cycle genes,0,0,1,MCM6
121,ACTA2,pericyte marker,0,0,1,ACTA2
122,PVALB,marker of pvalb GABAergic cortinal interneuron,0,0,1,PVALB
123,LAMP5,marker of lamp5 GABAergic cortical interneuron,0,0,1,LAMP5
124,CALB2,"vip GABAergic cortinal interneuron, literature + DE in reference dataset",0,0,1,CALB2
125,SNCG,projecting glutaminergic cortical,0,0,1,SNCG
126,SYT6,DE in microglia in reference dataset,0,0,1,SYT6
127,SOX9,astrocyte marker literature,0,0,1,SOX9
128,SLC7A10,neural stem cells marker /astrocyte suptype marker from lit,0,0,1,SLC7A10
129,ID3,astrocyte suptype marker from lit,0,0,1,ID3
130,WFS1,astrocyte suptype marker from lit,0,0,1,WFS1
131,FAM107A,astrocyte suptype marker from lit,0,0,1,FAM107A
132,ZNF488,mature oligodendrocyte marker,0,0,1,ZNF488
133,CHRNA2,"vip GABAergic cortinal interneuron, literature + DE in reference dataset",0,0,1,CHRNA2
134,PTPRC,immune marker,0,0,1,PTPRC
135,CEBPB,senescent microglia marker,0,0,1,CEBPB
136,NLRP3,,0,0,1,NLRP3
137,CHODL,"oligodendrocyte marker in literature, DE in reference dataset",0,0,1,CHODL
138,ANXA5,oligodendrocyte subtype marker in literature,0,0,1,ANXA5
139,OTOF,"sstGABAergic cortinal interneuron, lit, DE",0,0,1,OTOF
140,MAL,genes linked to myelination,0,0,1,MAL
141,PRKX,genes linked to inflammation/immune response,0,0,1,PRKX
142,FRZB,astrocyte suptype marker from lit,0,0,1,FRZB
143,S100B,astrocyte marker literature,0,0,1,S100B
144,NPY,Cell-cell signaling,0,0,1,NPY
145,PCDH8,Cell-cell signaling,0,0,1,PCDH8
146,TSPAN2,genes linked to myelination,0,0,1,TSPAN2
147,COX8A,gene linked to metabolic alteratsion,0,0,1,COX8A
148,RPN1,Proteosome,0,0,1,RPN1
149,RELB,inflammatory microglial marker gene,0,0,1,RELB
150,NDUFS7,gene linked to metabolic alteratsion,0,0,1,NDUFS7