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- ---
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- license: mit
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- ---
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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+ ---
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+ configs:
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+ - config_name: ncbi_summary
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+ data_files: "ncbi_summary.parquet"
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+ default: true
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+ - config_name: ncbi_uniprot_summary
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+ data_files: "ncbi_uniprot_summary.parquet"
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+ - config_name: gene_info
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+ data_files: "gene_info.parquet"
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+ - config_name: generated_descriptions_gpt4o_mini_combined
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+ data_files: "generated_descriptions_gpt4o_mini_combined.parquet"
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+ ---
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+
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+ ---
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+
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+ # Gene Description Dataset
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+
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+ This dataset reproduces and expands upon the GenePT project and paper, and makes it easier to reproce and access using standard tools.
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+ The goal is to allow users to compose embeddings across dimensions in order to specialize for specific tasks, and add to the existing
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+ base embeddings by generating new descriptions and embedding them in the same space.
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+
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+ ## Dataset Description
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+
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+ This dataset
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+ 1. reproduces the data from the GenePT project and paper in a more easy-to-use format. This paper itself aggregates data from multiple sources, so please refer to the paper and repository for detailed source information.
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+ Citation: Chen YT, Zou J. (2023+) GenePT: A Simple But Effective Foundation Model for Genes and Cells Built From ChatGPT. bioRxiv preprint: https://www.biorxiv.org/content/10.1101/2023.10.16.562533v2.
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+ GitHub: https://github.com/yiqunchen/GenePT
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+ 2. Adds descriptions of genes extracted from various LLMs, across multiple dimensions, such as regulatory pathways, drug interactions, etc. Currently we use GPT-4o-mini to generate descriptions, and only
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+ have a combined description that includes several factors. We will add composable dimensions soon
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+
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+ ## Dataset Structure
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+
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+ The dataset contains four main components:
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+
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+ 1. NCBI Summary
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+ - Contains gene descriptions from NCBI
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+ 2. NCBI-UniProt Summary
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+ - Contains combined gene descriptions from NCBI and UniProt
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+ 3. Gene Info Table
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+ - Contains contains a mapping between gene_id, ensmble_id and gene functional annotation
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+ 4. Generated Descriptions (Combined)
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+ - Contains AI-generated gene descriptions
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+ - Model: GPT-4o-mini
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+ - Factors:
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+ a. Associated genes
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+ b. Aging related information
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+ c. Drug interactions
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+ d. Pathways and biological processes
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+
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+ ## Dataset Creation
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+
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+ Source Data:
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+ - NCBI Gene Database
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+ - UniProt Database
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+