Upload README.md with huggingface_hub
Browse files
README.md
CHANGED
|
@@ -1,3 +1,55 @@
|
|
| 1 |
-
---
|
| 2 |
-
|
| 3 |
-
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
---
|
| 2 |
+
configs:
|
| 3 |
+
- config_name: ncbi_summary
|
| 4 |
+
data_files: "ncbi_summary.parquet"
|
| 5 |
+
default: true
|
| 6 |
+
- config_name: ncbi_uniprot_summary
|
| 7 |
+
data_files: "ncbi_uniprot_summary.parquet"
|
| 8 |
+
- config_name: gene_info
|
| 9 |
+
data_files: "gene_info.parquet"
|
| 10 |
+
- config_name: generated_descriptions_gpt4o_mini_combined
|
| 11 |
+
data_files: "generated_descriptions_gpt4o_mini_combined.parquet"
|
| 12 |
+
---
|
| 13 |
+
|
| 14 |
+
---
|
| 15 |
+
|
| 16 |
+
# Gene Description Dataset
|
| 17 |
+
|
| 18 |
+
This dataset reproduces and expands upon the GenePT project and paper, and makes it easier to reproce and access using standard tools.
|
| 19 |
+
The goal is to allow users to compose embeddings across dimensions in order to specialize for specific tasks, and add to the existing
|
| 20 |
+
base embeddings by generating new descriptions and embedding them in the same space.
|
| 21 |
+
|
| 22 |
+
## Dataset Description
|
| 23 |
+
|
| 24 |
+
This dataset
|
| 25 |
+
1. reproduces the data from the GenePT project and paper in a more easy-to-use format. This paper itself aggregates data from multiple sources, so please refer to the paper and repository for detailed source information.
|
| 26 |
+
Citation: Chen YT, Zou J. (2023+) GenePT: A Simple But Effective Foundation Model for Genes and Cells Built From ChatGPT. bioRxiv preprint: https://www.biorxiv.org/content/10.1101/2023.10.16.562533v2.
|
| 27 |
+
GitHub: https://github.com/yiqunchen/GenePT
|
| 28 |
+
2. Adds descriptions of genes extracted from various LLMs, across multiple dimensions, such as regulatory pathways, drug interactions, etc. Currently we use GPT-4o-mini to generate descriptions, and only
|
| 29 |
+
have a combined description that includes several factors. We will add composable dimensions soon
|
| 30 |
+
|
| 31 |
+
## Dataset Structure
|
| 32 |
+
|
| 33 |
+
The dataset contains four main components:
|
| 34 |
+
|
| 35 |
+
1. NCBI Summary
|
| 36 |
+
- Contains gene descriptions from NCBI
|
| 37 |
+
2. NCBI-UniProt Summary
|
| 38 |
+
- Contains combined gene descriptions from NCBI and UniProt
|
| 39 |
+
3. Gene Info Table
|
| 40 |
+
- Contains contains a mapping between gene_id, ensmble_id and gene functional annotation
|
| 41 |
+
4. Generated Descriptions (Combined)
|
| 42 |
+
- Contains AI-generated gene descriptions
|
| 43 |
+
- Model: GPT-4o-mini
|
| 44 |
+
- Factors:
|
| 45 |
+
a. Associated genes
|
| 46 |
+
b. Aging related information
|
| 47 |
+
c. Drug interactions
|
| 48 |
+
d. Pathways and biological processes
|
| 49 |
+
|
| 50 |
+
## Dataset Creation
|
| 51 |
+
|
| 52 |
+
Source Data:
|
| 53 |
+
- NCBI Gene Database
|
| 54 |
+
- UniProt Database
|
| 55 |
+
|