---
Author: hy3074
Date: 25.11.24
Description: Synthetic DNA-to-AA ORF Translation Dataset
tags:
- dna
- protein
- bioinformatics
- synthetic-biology
- sequence-to-sequence
- translation
tasks:
- sequence-to-sequence
language:
- en
dataset_info:
  features:
  - name: src
    dtype: string
  - name: tgt
    dtype: string
  splits:
  - name: train
    num_bytes: 3332329
    num_examples: 4900
  - name: validation
    num_bytes: 476047
    num_examples: 700
  - name: test
    num_bytes: 952094
    num_examples: 1400
  download_size: 2371456
  dataset_size: 4760470
configs:
- config_name: default
  data_files:
  - split: train
    path: data/train-*
  - split: validation
    path: data/validation-*
  - split: test
    path: data/test-*
---

# Synthetic DNA → Amino Acid ORF Translation Dataset

## 🧬 Summary

This dataset contains **synthetic DNA sequences** (`src`) and their corresponding **amino acid sequences** (`tgt`), where the label is defined as the **first valid ORF** from the 5' end:

> From the **first `ATG`** (start codon) encountered in the sequence  
> to the **first in-frame stop codon** (`TAA`, `TAG`, or `TGA`) that follows it,  
> translated into amino acids (excluding the stop).

The dataset is designed for training and evaluating models that learn **DNA→protein translation rules** and **ORF detection** in a slightly non-trivial, noisy setting.

---

## 📁 Dataset Structure

### Data fields

Each example is a JSON object with the following fields:

- `src` (string):  
  A DNA sequence (characters `A`, `C`, `G`, `T` only).  
  - Length is **variable**, from a minimum (e.g. 6 nt) up to a specified maximum.
  - The sequence is mostly random, but guaranteed to contain at least one valid ORF.

- `tgt` (string):  
  The amino acid sequence translated from the ORF defined as:
  - The first `ATG` found when scanning from the 5' end.
  - The first **in-frame** stop codon (`TAA`, `TAG`, `TGA`) after that `ATG`.
  - Translation uses the **standard genetic code**.
  - The stop codon is **not included** in the amino acid string.

Example (conceptual):

```json
{
  "src": "ACGTTGATGAAAACCGGGTAGTTCG...",
  "tgt": "MKTVG"
}