A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.


A deficiency of folate decreases blood levels of homocysteine.


Adult tissue-resident macrophages are maintained independent of circulating monocytes.


Amitriptyline ineffective as a treatment for chronic tension-type headaches.


Antibiotic induced alterations in the gut microbiome increase resistance against Clostridium difficile


Autophagy increases in aged organisms.


BRCA 1 mutation carriers' risk of breast and ovarian cancer  is not influence by the location of the mutation.


Bariatric surgery has a deleterious impact on mental health.


Bariatric surgery reduces resolution of diabetes.


CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving cancer metastasis.


CHEK2 has a significant role in breast cancer


CRY proteins mediate light signal transduction.


Chronic aerobic exercise alters endothelial function, impairing vasodilating mechanisms mediated by NO.


Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is ineffective at treating KRAS mutant tumors.


Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.


Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.


Gene expression can be highly variable across genetically identical cells.


High cardiopulmonary fitness causes decreased mortality rate.


Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.


IL-10 production by monocytes encourages CD4 + T cell response.


Incidence rates of cervical cancer have increased over time.


MEK inhibitors are not effective in RAS-driven mouse models of cancer.


Metastases have genomic aberrations different than those of the primary tumor.


Mitochondria are uninvolved in processes related to cell signaling.


Mitochondria play a major role in calcium homeostasis.


Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.


Myelin sheaths play an important role in trophic support.


Obesity decreases life expectancy.


Obesity is determined in part by genetic factors.


Obesity prolongs life expectancy.


Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.


Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.


Risedronate reduces risk of vertebral and non-vertebral fractures.


Satellite cell dysfunction is not a key factor in sarcopenia development.


Serotonin receptors have no effect on depression


Serotonin receptors play a role in depression


Sustained transmission of Avian influenza A between humans is not observed.


Teaching hospitals provide better care than non-teaching hospitals.


The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.


The risk of cancer is lower in individuals with a history of heavy alcohol consumption.


There is no relation between lupus erythematosus and cardiovascular disease


Whole brain radiotherapy reduces the occurrence of new brain metastases.


c-MYC is important for maintaining pluripotent state of pluripotent stem cells.