File size: 7,645 Bytes
a44124f
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
#!/usr/bin/env python3
"""
V3Cell video generation (inference) script.

Loads a trained V3CellGenerator checkpoint and generates organoid development
videos unconditionally (noise → MotionRNN → R3GAN → frames).

Usage:
    python scripts/generate.py \\
        --checkpoint checkpoints/outputs/v3cell/checkpoint_002000.pt \\
        --r3gan_ckpt checkpoints/training-runs/00002-frames-256-gpus3-batch96/network-snapshot-000000580.pkl \\
        --n_videos 10 \\
        --n_frames 16 \\
        --output_dir outputs/generated
"""

import argparse
import sys
from pathlib import Path

project_root = Path(__file__).parent.parent
sys.path.insert(0, str(project_root))

import torch
from tqdm import tqdm

from models import V3CellGenerator
from utils import load_config, set_seed, save_video_as_gif


def parse_args():
    parser = argparse.ArgumentParser(description='Generate videos with V3Cell')

    # Required arguments
    parser.add_argument('--checkpoint', type=str, required=True,
                        help='Path to V3Cell checkpoint (.pt)')
    parser.add_argument('--r3gan_ckpt', type=str, required=True,
                        help='Path to R3GAN checkpoint (.pkl)')

    # Optional paths
    parser.add_argument('--config', type=str, default='configs/default.yaml',
                        help='Path to YAML config file')
    parser.add_argument('--output_dir', type=str, default='outputs/generated',
                        help='Output directory for generated videos')
    parser.add_argument('--r3gan_path', type=str, default=None,
                        help='Path to external R3GAN source (usually not needed)')

    # Generation parameters
    parser.add_argument('--n_videos', type=int, default=10,
                        help='Total number of videos to generate')
    parser.add_argument('--n_frames', type=int, default=16,
                        help='Number of frames per video')
    parser.add_argument('--class_idx', type=int, default=None,
                        help='Class index to generate (None = generate all classes)')
    parser.add_argument('--batch_size', type=int, default=4,
                        help='Batch size for generation')

    # Output format
    parser.add_argument('--format', type=str, default='gif',
                        choices=['gif', 'mp4', 'png'],
                        help='Output format: gif, mp4, or png (frame sequence)')
    parser.add_argument('--fps', type=int, default=10,
                        help='Frames per second for video output')

    parser.add_argument('--seed', type=int, default=42)
    parser.add_argument('--gpu', type=int, default=0)

    # Architecture flags — must match the settings used to train --checkpoint
    # (see scripts/train_conditional.py, which defaults to content-motion
    # separation with content_dim=32; inference.py hardcodes the same values).
    parser.add_argument('--use_content_motion', action='store_true', default=True,
                        help='Build the generator with MoCoGAN-style content/motion latent separation')
    parser.add_argument('--no_content_motion', action='store_true',
                        help='Disable content-motion separation (use a single shared z_dim)')
    parser.add_argument('--content_dim', type=int, default=32,
                        help='Content latent dimension (only used if content-motion separation is enabled)')

    return parser.parse_args()


def main():
    args = parse_args()

    device = torch.device(f'cuda:{args.gpu}' if torch.cuda.is_available() else 'cpu')
    print(f"Using device: {device}")

    set_seed(args.seed)

    # Load configuration.
    config_path = project_root / args.config
    if config_path.exists():
        config = load_config(config_path)
    else:
        print(f"Config not found at {config_path} — using built-in defaults.")
        config = {
            'model': {
                'z_dim': 64,
                'c_dim': 3,
                'img_resolution': 256,
                'motion_rnn': {
                    'hidden_dim': 384,
                    'num_layers': 2,
                    'dropout': 0.1,
                    'residual_weight': 0.2,
                },
            },
        }

    model_cfg = config['model']

    output_dir = Path(args.output_dir)
    output_dir.mkdir(parents=True, exist_ok=True)

    # Build and load model.
    use_content_motion = args.use_content_motion and not args.no_content_motion
    print("Loading V3Cell model...")
    print(f"  Content-motion separation: {use_content_motion} (content_dim={args.content_dim})")
    generator = V3CellGenerator(
        r3gan_checkpoint=args.r3gan_ckpt,
        z_dim=model_cfg['z_dim'],
        c_dim=model_cfg['c_dim'],
        motion_hidden_dim=model_cfg['motion_rnn']['hidden_dim'],
        motion_num_layers=model_cfg['motion_rnn']['num_layers'],
        motion_dropout=model_cfg['motion_rnn']['dropout'],
        residual_weight=model_cfg['motion_rnn']['residual_weight'],
        use_content_motion=use_content_motion,
        content_dim=args.content_dim,
        freeze_r3gan=True,
        r3gan_path=args.r3gan_path,
    )

    checkpoint = torch.load(args.checkpoint, map_location='cpu')
    generator.load_trainable_state_dict(checkpoint['generator'])
    generator = generator.to(device).eval()

    print(f"Loaded checkpoint: {args.checkpoint}")

    # Determine which classes to generate.
    class_indices = [args.class_idx] if args.class_idx is not None \
        else list(range(model_cfg['c_dim']))

    print(f"\nGenerating {args.n_videos} videos × {args.n_frames} frames "
          f"for classes {class_indices} ...")

    video_idx = 0
    with torch.no_grad():
        for class_idx in class_indices:
            # Distribute n_videos evenly across classes.
            n_class_videos = args.n_videos // len(class_indices)
            if class_idx < args.n_videos % len(class_indices):
                n_class_videos += 1

            print(f"\nClass {class_idx}: generating {n_class_videos} videos")

            for batch_start in tqdm(range(0, n_class_videos, args.batch_size)):
                batch_size = min(args.batch_size, n_class_videos - batch_start)

                z = generator.sample_z(batch_size, device)
                c = generator.sample_c(batch_size, device, class_idx=class_idx)

                # Generate and rescale from [-1, 1] to [0, 1].
                videos = generator(z, c, args.n_frames)
                videos = ((videos + 1) / 2).clamp(0, 1)

                for i, video in enumerate(videos):
                    if args.format == 'gif':
                        save_path = output_dir / f"video_{video_idx:04d}_class{class_idx}.gif"
                        save_video_as_gif(video, save_path, fps=args.fps)

                    elif args.format == 'mp4':
                        from utils.misc import save_video_as_mp4
                        save_path = output_dir / f"video_{video_idx:04d}_class{class_idx}.mp4"
                        save_video_as_mp4(video, save_path, fps=args.fps)

                    elif args.format == 'png':
                        # Save each frame as a separate PNG.
                        vid_dir = output_dir / f"video_{video_idx:04d}_class{class_idx}"
                        vid_dir.mkdir(exist_ok=True)
                        for t, frame in enumerate(video):
                            from torchvision.utils import save_image
                            save_image(frame, vid_dir / f"frame_{t:04d}.png")

                    video_idx += 1

    print(f"\nGenerated {video_idx} videos → {output_dir}")


if __name__ == '__main__':
    main()