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%% Classify Scalars
clear all; clc

% Set the random seed
RandStream.setGlobalStream(RandStream('mt19937ar','seed',sum(100*clock)));

% Data are here
cd('Y:\EEG_Data\CLASSIFY\Classify for Arun\');



% Load up IDs, match with CTL IDs, get correlates

[EEG_IDs,~,~]=xlsread('All_POWER_ROI_INFO.xlsx','Subjects_IDs'); % Col 1 = Pd, Col 2 = CTL

[VAR_DATA,VAR_HDR,VAR_BOTH]=xlsread('PD_CONFLICT_VARS.xlsx');

% Match up

PD_ID=VAR_DATA(:,1);

MATCH_ID=VAR_DATA(:,5);

YrsDx=VAR_DATA(:,9);

if sum( EEG_IDs(:,1)==PD_ID )==28  % If PD are numerically aligned in both data sets

    for matchi=1:28

        MATCHTOEEG(matchi)=find( EEG_IDs(:,2)==MATCH_ID(matchi) ); % Find the ctl subj that matches with this patient

    end

end



% Load EEG Data

SHEET={'Cue_locked_Conf','Response_locked_Conf','Response-locked_CorrectError','PostCorrectError','Alpha','RelativeAlpha'};

for sheeti=1:6

    [DATA{sheeti},HDR{sheeti},BOTH{sheeti}]=xlsread('All_POWER_ROI_INFO.xlsx',SHEET{sheeti});

end



% ********* Setup Data *********   Do you want control only, or control-benign condi diffs?

for sheeti=1:4

    CTL(:,sheeti)=DATA{sheeti}(:,3) % -DATA{sheeti}(:,2);

    ON(:,sheeti)=DATA{sheeti}(:,5) % -DATA{sheeti}(:,4);

    OFF(:,sheeti)=DATA{sheeti}(:,7) % -DATA{sheeti}(:,6);

end

% Alpha

for sheeti=5:6

    CTL(:,sheeti)=DATA{sheeti}(:,1)  ;

    ON(:,sheeti)=DATA{sheeti}(:,2)  ;

    OFF(:,sheeti)=DATA{sheeti}(:,3) ;

end





% ********* Setup Contrasts *********  InData should have Col 1 = group (1=patient, 0=Ctl) and Cols 2-N are data

InData=[  [ones(28,1),CTL] ; [zeros(28,1),ON]  ] ;

TITLE='CTL_ON_NoDiff';

iterations=500;

vars=[2,3,4,5,6]  % [2,3,4,5,7];  % Column 1 is group, 2-N are variables to select any number of here

% ********* ***** *********



% Classify

for Xvali=1:3

    if     Xvali==1, Xval='5X';

    elseif Xvali==2, Xval='10X';

    elseif Xvali==3, Xval='LOO';

    end

    Classify_Scalars_SVM(InData,TITLE,iterations,vars,Xval);

    Classify_Scalars_LASSO(InData,TITLE,iterations,vars,Xval);  % not fully validated, just playing with this for now.

end

% Now each paired with their best match CTL

Classify_Scalars_SVM_MatchSubjs(InData,TITLE,MATCHTOEEG,vars,'Match');

Classify_Scalars_LASSO_MatchSubjs(InData,TITLE,MATCHTOEEG,vars,'Match');



%% Aggregate Different Predictors / SVM



% ########################

Xval='LOO';

iterations=500;  % If 'Match', iterations needs to = 28

Classifier='SVM';  % 'SVM'  'LASSO'

% TITLE={'CTL_ON_Cue','CTL_ON_Resp','CTL_ON_Err','CTL_ON_PE','CTL_ON_RelAlpha','CTL_ON'};   

 TITLE={'CTL_OFF_Cue','CTL_OFF_Resp','CTL_OFF_Err','CTL_OFF_PE','CTL_OFF_RelAlpha','CTL_OFF'}; 

% TITLE={'CTL_ON_NoDiff_Cue','CTL_ON_NoDiff_Resp','CTL_ON_NoDiff_Err','CTL_ON_NoDiff_PE','CTL_ON_NoDiff_Alpha','CTL_ON_NoDiff'};  % not C-I diff 

% ########################



for vari=1:6

        

    if strmatch(Classifier,'SVM')

        load(['SVM_',TITLE{vari},'_',Xval,'_iter',num2str(iterations),'.mat']);

        OUTPUTS(vari,1)=mean(mean(Aset_acc));

        OUTPUTS(vari,2)=mean(mean(Bset_acc));

        if strmatch(Xval,'Match')

            SCORES(vari,1,:)=Aset_score;

            SCORES(vari,2,:)=Bset_score;

        else

            SCORES(vari,1,:)=nanmean(Aset_score');
            SCORES(vari,2,:)=nanmean(Bset_score');            

        end

        clear A* B*;  classifier=1;

        

    elseif strmatch(Classifier,'LASSO')

        load(['LASSO_',TITLE{vari},'_',Xval,'_iter',num2str(iterations),'.mat']);

        OUTPUTS(vari,1)=mean(LASSO_Probability_Tst2(:,2));

        OUTPUTS(vari,2)=mean(LASSO_Probability_Tst2(:,3));

        if strmatch(Xval,'Match')

            if vari==6

                SCORES(vari,1,:)=LASSO_Betas(LASSO_Betas==max(abs(LASSO_Betas)')');

                SCORES(vari,2,:)=LASSO_Betas(LASSO_Betas==max(abs(LASSO_Betas)')');

            else

                SCORES(vari,1,:)=LASSO_Betas;

                SCORES(vari,2,:)=LASSO_Betas;

            end

        end

        clear A* B*; classifier=2;

    end

    

end





% Plot

COL={'m','y'};

SHAPE={'d','o','s','p','h','^'};



figure;

subplot(1,3,1:2);

hold on

for vari=1:6

    plot(1-OUTPUTS(vari,2),OUTPUTS(vari,1),...

        SHAPE{vari},'MarkerFaceColor','k','MarkerEdgeColor',COL{classifier},'MarkerSize',10)

end

set(gca,'ylim',[0 1],'ytick',[0:.1:1],'xlim',[0 1],'xtick',[0:.1:1]);

legend(TITLE,'location','southeast', 'Interpreter', 'none');

ylabel('Sensitivity'); xlabel('1-Specificity');

plot([0 1],[0 1],'k');

title(['Classification of ',TITLE{6}], 'Interpreter', 'none')



subplot(1,3,3);

hold on

for vari=1:6

    bar(vari,mean(OUTPUTS(vari,:),2),.4,COL{classifier})

end

set(gca,'ylim',[.4 1],'ytick',[.4:.1:1],'xlim',[0 7],'xtick',[1:1:6],'xticklabels',TITLE);

xtickangle(90)

title('Average')



if strmatch(Classifier,'SVM')

    figure;

    for paneli=1:6

        subplot(2,3,paneli); hold on

        scatter(YrsDx,abs(squeeze(SCORES(paneli,1,:)))); lsline

        [rho,p]=corr(abs(squeeze(SCORES(paneli,1,:))),YrsDx,'type','Spearman');

        text(.1,.1,['rho=',num2str(rho),' p=',num2str(p)],'sc');

        xlabel('YrsDx'); ylabel('confidence');

        title(TITLE{paneli}, 'Interpreter', 'none')

    end

end



% Aggregate all X-Vals and Algorithms

ToAgg=6; iterations=500;



for Xvali=1:3

    if     Xvali==1, Xval='5X';

    elseif Xvali==2, Xval='10X';

    elseif Xvali==3, Xval='LOO';

    end

    load(['SVM_',TITLE{ToAgg},'_',Xval,'_iter',num2str(iterations),'.mat']);

    OUTPUT_AGG(1,Xvali,1)=mean(mean(Aset_acc));

    OUTPUT_AGG(1,Xvali,2)=mean(mean(Bset_acc));

    clear A* B*;

    

    load(['LASSO_',TITLE{ToAgg},'_',Xval,'_iter',num2str(iterations),'.mat']);

    OUTPUT_AGG(2,Xvali,1)=mean(LASSO_Probability_Tst2(:,2));

    OUTPUT_AGG(2,Xvali,2)=mean(LASSO_Probability_Tst2(:,3));

    clear LASSO*;

end



load(['SVM_',TITLE{ToAgg},'_Match_iter28.mat']);

OUTPUT_AGG(1,4,1)=mean(mean(Aset_acc));

OUTPUT_AGG(1,4,2)=mean(mean(Bset_acc));

clear A* B*;



load(['LASSO_',TITLE{ToAgg},'_Match_iter28.mat']);

OUTPUT_AGG(2,4,1)=mean(LASSO_Probability_Tst2(:,2));

OUTPUT_AGG(2,4,2)=mean(LASSO_Probability_Tst2(:,3));

clear LASSO*;



% Plot

COL={'m','y'};

SHAPE={'d','o','s','p'};

SHIFT=[-.2,-.1,.1,.2];



figure;

subplot(1,3,1:2);

hold on

for classifier=1:2

    for Xvali=1:4

        plot(1-OUTPUT_AGG(classifier,Xvali,2),OUTPUT_AGG(classifier,Xvali,1),...

            SHAPE{Xvali},'MarkerFaceColor','k','MarkerEdgeColor',COL{classifier},'MarkerSize',10)

    end

end

set(gca,'ylim',[0 1],'ytick',[0:.1:1],'xlim',[0 1],'xtick',[0:.1:1]);

legend({'SVM 5X','SVM 10X','SVM LOO','SVM Match','LASSO 5X','LASSO 10X','LASSO LOO','LASSO Match'},'location','southeast');

ylabel('Sensitivity'); xlabel('1-Specificity');

plot([0 1],[0 1],'k');

title(['Classification of ',TITLE{ToAgg}], 'Interpreter', 'none')



subplot(1,3,3);

hold on

for classifier=1:2

    for Xvali=1:4

        bar(classifier+SHIFT(Xvali),mean(OUTPUT_AGG(classifier,Xvali,:),3),.4,COL{classifier})

    end

end

set(gca,'ylim',[.5 1],'ytick',[.5:.1:1],'xlim',[0 3],'xtick',[1:1:2],'xticklabels',{'SVM','LASSO'});

title('Average')





%%