%% ERPs clear ; clc; close all; savedir='D:\Project_EEG_CC\CC_Results_step2_AllChannels_NEW\'; cd(savedir); load('D:\Project_EEG_CC\mFiles\ONOFF.mat','ONOFF') load('D:\Project_EEG_CC\mFiles\BV_Chanlocs_60.mat'); PDsx=[801:811,813:829]; CTLsx=[8010,8070,8060,890:914]; BigN=size(ONOFF,1)./2; % load PD OFF and ON data row=1; for mi=1:size(ONOFF,1) disp([num2str(ONOFF(mi,1)),'_Session_',num2str(ONOFF(mi,2)),'_PDDys_CC_ALL_GOODS.mat']); if ONOFF(mi,1)==824 && ONOFF(mi,2)==2 % Bad EEG VECTOR=NaN; ERPs=NaN(size_erp); POWER=NaN(size_power); else load([savedir,num2str(ONOFF(mi,1)),'_Session_',num2str(ONOFF(mi,2)),'_PDDys_CC_ALL_GOODS.mat']); size_erp=size(ERPs); size_power=size(POWER); end if ONOFF(mi,3)==1 % ON ON.ID(floor(row))=ONOFF(mi,1); ON.Session(floor(row))=ONOFF(mi,2); ON.ERPs(floor(row),:,:,:,:)=ERPs; ON.POWER{1}(floor(row),:,:,:,:,:)=POWER; elseif ONOFF(mi,3)==0 % OFF OFF.ID(floor(row))=ONOFF(mi,1); OFF.Session(floor(row))=ONOFF(mi,2); OFF.ERPs(floor(row),:,:,:,:)=ERPs; OFF.POWER{1}(floor(row),:,:,:,:,:)=POWER; end row=row+.5; clear ERPs Model_Output POWER ITPC; end % load control data row=1; for CTLi=CTLsx; disp([num2str(CTLi),'_Session_1_PDDys_CC_ALL_GOODS.mat']); if ONOFF(mi,1)==911 && ONOFF(mi,2)==1 % Bad EEG VECTOR=NaN; ERPs=NaN(size_erp); POWER=NaN(size_power); else load([savedir,num2str(CTLi),'_Session_1_PDDys_CC_ALL_GOODS.mat']); end CTL.ID(floor(row))=CTLi; CTL.Session(floor(row))=1; CTL.ERPs(floor(row),:,:,:,:)=ERPs; CTL.POWER{1}(floor(row),:,:,:,:,:)=POWER; row=row+1; clear ERPs Model_Output POWER; end CtlN=row-1; %% % ######################## Response - locked ERPs ################# tx2disp=-500:2:1000; CHAN=21; % Cz paneli = 2; % response %%%% for Control subplot(321) shadedErrorBar2(tx2disp,squeeze(nanmean(CTL.ERPs(:,CHAN,:,1,paneli),1)),squeeze(nanstd(CTL.ERPs(:,CHAN,:,1,paneli),1))./sqrt(28),'lineprops','b');hold on plot(tx2disp,squeeze(nanmean(CTL.ERPs(:,CHAN,:,1,paneli),1)),'b','linewidth',2); hold on shadedErrorBar2(tx2disp,squeeze(nanmean(CTL.ERPs(:,CHAN,:,2,paneli),1)),squeeze(nanstd(CTL.ERPs(:,CHAN,:,2,paneli),1))./sqrt(28),'lineprops','c');hold on plot(tx2disp,squeeze(nanmean(CTL.ERPs(:,CHAN,:,2,paneli),1)),'c','linewidth',2); hold on plot([0 0],[-5 10],'k:'); title(' Control: Cz');hold off; box off; ylim([-3 8]); %%%% for PD ON subplot(323) shadedErrorBar2(tx2disp,squeeze(nanmean(ON.ERPs(:,CHAN,:,1,paneli),1)),squeeze(nanstd(ON.ERPs(:,CHAN,:,1,paneli),1))./sqrt(28),'lineprops','r');hold on plot(tx2disp,squeeze(nanmean(ON.ERPs(:,CHAN,:,1,paneli),1)),'r','linewidth',2); hold on shadedErrorBar2(tx2disp,squeeze(nanmean(ON.ERPs(:,CHAN,:,2,paneli),1)),squeeze(nanstd(ON.ERPs(:,CHAN,:,2,paneli),1))./sqrt(28),'lineprops','m');hold on plot(tx2disp,squeeze(nanmean(ON.ERPs(:,CHAN,:,2,paneli),1)),'m','linewidth',2); hold on plot([0 0],[-5 10],'k:'); title('PD ON: Cz');hold off; box off; ylim([-3 8]); % % % ################## Time Frequency ##################### tx2disp=-500:2:1000; frex=logspace(.01,1.7,50); Bidx=1; % 1 is pre-cue baseline CHANI=21; % Cz EVENT=2; % RESP %%%%%%%%%%%%%%%%%%%%%%%%% %%% figure for PD OFF/ON - Control CTL_Conf2 = CTL.POWER{Bidx}(:,CHANI,:,:,2,EVENT); CTL_Conf1 = CTL.POWER{Bidx}(:,CHANI,:,:,1,EVENT); ON_Conf2 = ON.POWER{Bidx}(:,CHANI,:,:,2,EVENT); ON_Conf1 = ON.POWER{Bidx}(:,CHANI,:,:,1,EVENT); CTL_Conf12 = (squeeze( nanmean(CTL_Conf2,1)) + squeeze( nanmean(CTL_Conf1,1)))/2; PD_ON_Conf12 = (squeeze( nanmean(ON_Conf2,1)) + squeeze( nanmean(ON_Conf1,1)))/2; CTL_Conf21 = squeeze( nanmean(CTL_Conf2,1)) - squeeze( nanmean(CTL_Conf1,1)); PD_ON_Conf21 = squeeze( nanmean(ON_Conf2,1)) - squeeze( nanmean(ON_Conf1,1)); % %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% CONTOL and PD ON %%%%%%%%%%%%%%%%%%%% %%% CTL-PD ON subplot(322); imagesc( tx2disp,[], (CTL_Conf12) - (PD_ON_Conf12) ); axis xy; hold on; colormap jet [Corrected_P] = Run_Thresh_2D( (squeeze(ON_Conf1)+squeeze(ON_Conf2))/2, (squeeze(CTL_Conf1)+ squeeze(CTL_Conf2))/2, 'between') ; contour(tx2disp,1:50,Corrected_P,'k','linewidth',2); clear Corrected_P; plot([0 0],[1 50],'k:') set(gca,'clim',[-2 2],'xlim',[-500,1000],'ylim',[1 50],'YTick',1:4:length(frex),'YTickLabel',round(frex(1:4:end)));title('CTL-ON (Avg of Correct and Error)');hold off; %colorbar; subplot(324); imagesc(tx2disp,[], CTL_Conf21 - PD_ON_Conf21); axis xy; hold on; colormap jet [Corrected_P] = Run_Thresh_2D( squeeze(ON_Conf2)-squeeze(ON_Conf1), squeeze(CTL_Conf2)- squeeze(CTL_Conf1), 'between') ; contour(tx2disp,1:50,Corrected_P,'k','linewidth',2); clear Corrected_P; rectangle('Position',[-200 18 250 9],'EdgeColor','b','LineWidth', 3); plot([0 0],[1 50],'k:') set(gca,'clim',[-2 2],'xlim',[-500,1000],'ylim',[1 50],'YTick',1:4:length(frex),'YTickLabel',round(frex(1:4:end)));hold off; title('CTL-ON (Error-Correct)'); % % % ####################### TOPO ###################################### tx1 = find (tx2disp==-200); tx2 = find (tx2disp==50); % fq1 = min(find(frex>3)); fq2 = min(find(frex>5)); fq1 = min(find(frex>3.8)); fq2 = min(find(frex>7.8)); for n = 1:28 for Chanl = 1:60 CTL_PowCg = CTL.POWER{1}(n,Chanl,(fq1:fq2),(tx1:tx2),1,paneli); ON_PowCg = ON.POWER{1} (n,Chanl,(fq1:fq2),(tx1:tx2),1,paneli); CTL_PowIncg = CTL.POWER{1}(n,Chanl,(fq1:fq2),(tx1:tx2),2,paneli); ON_PowIncg = ON.POWER{1} (n,Chanl,(fq1:fq2),(tx1:tx2),2,paneli); %%%% Incong and Cong .... IngPow_CTL = squeeze(nanmean(CTL_PowIncg)); CogPow_CTL = squeeze(nanmean(CTL_PowCg)); IngPow_ON = squeeze(nanmean(ON_PowIncg)); CogPow_ON = squeeze(nanmean(ON_PowCg)); IncongCTL(n).chans{Chanl,1} = nanmean(IngPow_CTL); CongCTL(n).chans{Chanl,1} = nanmean(CogPow_CTL); IncongON(n).chans{Chanl,1} = nanmean(IngPow_ON); CongON(n).chans{Chanl,1} = nanmean(CogPow_ON); end end IncongruentCTL = cell(28,60);CongruentCTL = cell(28,60); IncongruentON = cell(28,60);CongruentON = cell(28,60); for n = 1:28 IncongruentCTL(n,:) = IncongCTL(n).chans ; CongruentCTL(n,:) = CongCTL(n).chans ; IncongruentON(n,:) = IncongON(n).chans ; CongruentON(n,:) = CongON(n).chans ; end IncongruentCTL = cell2mat(IncongruentCTL); CongruentCTL = cell2mat(CongruentCTL); IncongruentON = cell2mat(IncongruentON); CongruentON = cell2mat(CongruentON); chanlocs = BV_Chanlocs_60; CTL_IncongCong = (IncongruentCTL - CongruentCTL); ON_IncongCong = (IncongruentON - CongruentON); % figure [~,P3,~,~]=ttest2(CTL_IncongCong,ON_IncongCong); P3(P3>=.05)=NaN; P3(P3<.05)=1; P3(isnan(P3))=0; subplot(326); topoplot(nanmean(CTL_IncongCong-ON_IncongCong),chanlocs,'maplimits',[-0.5 0.5],'emarker2', {find(P3),'d','k',5,1}); title ('Control-PD');colormap jet; clear P3 suptitle ('Response-locked ERPs-TF-TOPO: Conf2 and Conf1')