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biology
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protein-protein-interaction
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6d1bbc7 | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 | #!/usr/bin/env python3
"""Run LLM-as-Judge evaluation for GE-L3 reasoning predictions.
Reads GE-L3 predictions, sends through judge model, computes scores.
Usage:
python scripts_depmap/run_ge_l3_judge.py --judge-provider gemini --judge-model gemini-2.5-flash
python scripts_depmap/run_ge_l3_judge.py --run-dir results/ge_llm/ge-l3_qwen2-5-7b-instruct_3-shot_fs0
Output per run:
results/ge_llm/{run}_judged/
judge_scores.jsonl, results.json, judge_meta.json
"""
import argparse
import json
import time
from datetime import datetime, timezone
from pathlib import Path
from negbiodb.llm_client import LLMClient
from negbiodb_depmap.llm_eval import GE_L3_JUDGE_PROMPT, evaluate_ge_l3, parse_ge_l3_judge_scores
PROJECT_ROOT = Path(__file__).resolve().parent.parent
RESULTS_DIR = PROJECT_ROOT / "results" / "ge_llm"
DATA_DIR = PROJECT_ROOT / "exports" / "ge_llm"
L3_DATASET_FILE = DATA_DIR / "ge_l3_dataset.jsonl"
def load_gold_records() -> list[dict]:
"""Load GE-L3 gold records."""
records = []
with open(L3_DATASET_FILE) as f:
for line in f:
records.append(json.loads(line))
return records
def load_predictions(pred_path: Path) -> list[dict]:
"""Load predictions from JSONL."""
preds = []
with open(pred_path) as f:
for line in f:
preds.append(json.loads(line))
return preds
def find_l3_runs(results_dir: Path) -> list[Path]:
"""Find all GE-L3 run directories."""
runs = []
for d in sorted(results_dir.iterdir()):
if d.is_dir() and d.name.startswith("ge-l3_"):
pred_file = d / "predictions.jsonl"
if pred_file.exists():
runs.append(d)
return runs
def judge_run(
run_dir: Path,
gold_records: list[dict],
client: LLMClient,
judge_model: str,
) -> dict:
"""Judge all predictions in a run directory."""
gold_by_id = {rec["question_id"]: rec for rec in gold_records}
predictions = load_predictions(run_dir / "predictions.jsonl")
judged_dir = run_dir.parent / f"{run_dir.name}_judged"
judged_dir.mkdir(parents=True, exist_ok=True)
# Resume support
scores_path = judged_dir / "judge_scores.jsonl"
completed = {}
if scores_path.exists():
with open(scores_path) as f:
for line in f:
rec = json.loads(line)
if rec.get("scores") is not None:
completed[rec["question_id"]] = rec
print(f" Resume: {len(completed)} already judged")
remaining = [p for p in predictions if p["question_id"] not in completed]
print(f" Judging {len(remaining)} remaining of {len(predictions)} total")
start_time = time.time()
with open(scores_path, "a") as f:
for i, pred_rec in enumerate(remaining):
qid = pred_rec["question_id"]
gold = gold_by_id.get(qid)
if gold is None:
print(f" Warning: no gold record for {qid}, skipping")
continue
prompt = GE_L3_JUDGE_PROMPT.format(
context_text=gold.get("context_text", ""),
response_text=pred_rec["prediction"],
)
try:
judge_response = client.generate(prompt)
except Exception as e:
print(f" Error judging {qid}: {e}")
judge_response = f"ERROR: {e}"
scores = parse_ge_l3_judge_scores(judge_response)
score_rec = {
"question_id": qid,
"judge_response": judge_response,
"scores": scores,
}
f.write(json.dumps(score_rec, ensure_ascii=False) + "\n")
f.flush()
completed[qid] = score_rec
if (i + 1) % 10 == 0:
elapsed = time.time() - start_time
rate = (i + 1) / elapsed * 60
print(f" Progress: {i + 1}/{len(remaining)} ({rate:.1f}/min)")
elapsed = time.time() - start_time
print(f" Judging complete: {elapsed:.0f}s")
# Aggregate — evaluate_ge_l3 expects raw judge response strings
all_outputs = []
for pred_rec in predictions:
qid = pred_rec["question_id"]
if qid in completed and completed[qid].get("judge_response"):
all_outputs.append(completed[qid]["judge_response"])
else:
all_outputs.append("")
metrics = evaluate_ge_l3(all_outputs)
with open(judged_dir / "results.json", "w") as f:
json.dump(metrics, f, indent=2)
meta = {
"judge_model": judge_model,
"source_run": run_dir.name,
"n_predictions": len(predictions),
"n_judged": sum(1 for o in all_outputs if o),
"elapsed_seconds": elapsed,
"timestamp": datetime.now(timezone.utc).isoformat(),
}
with open(judged_dir / "judge_meta.json", "w") as f:
json.dump(meta, f, indent=2)
return metrics
def main():
parser = argparse.ArgumentParser(description="Run GE-L3 LLM-as-Judge evaluation")
parser.add_argument("--run-dir", type=Path, default=None)
parser.add_argument("--results-dir", type=Path, default=RESULTS_DIR)
parser.add_argument("--judge-provider", default="gemini", choices=["gemini", "openai", "vllm"])
parser.add_argument("--judge-model", default="gemini-2.5-flash")
parser.add_argument("--api-base", default=None)
parser.add_argument("--api-key", default=None)
parser.add_argument("--temperature", type=float, default=0.0)
parser.add_argument("--max-tokens", type=int, default=512)
args = parser.parse_args()
print("Loading GE-L3 gold records...")
gold_records = load_gold_records()
test_records = [r for r in gold_records if r.get("split") == "test"]
print(f" Total: {len(gold_records)}, Test: {len(test_records)}")
print(f"\nInitializing judge: {args.judge_model} ({args.judge_provider})")
client = LLMClient(
provider=args.judge_provider,
model=args.judge_model,
api_base=args.api_base,
api_key=args.api_key,
temperature=args.temperature,
max_tokens=args.max_tokens,
)
if args.run_dir:
runs = [args.run_dir]
else:
runs = find_l3_runs(args.results_dir)
print(f" Found {len(runs)} GE-L3 runs to judge")
for run_dir in runs:
print(f"\n=== Judging: {run_dir.name} ===")
metrics = judge_run(run_dir, gold_records, client, args.judge_model)
for dim in ["biological_plausibility", "pathway_reasoning",
"context_specificity", "mechanistic_depth"]:
key_mean = f"{dim}_mean"
key_std = f"{dim}_std"
if key_mean in metrics:
print(f" {dim}: {metrics[key_mean]:.2f} +/- {metrics[key_std]:.2f}")
print(f" Overall: {metrics.get('overall_mean', 0):.2f} +/- {metrics.get('overall_std', 0):.2f}")
print(f" Parsed: {metrics.get('n_parsed', 0)}/{metrics.get('n_total', 0)}")
print(f"\n=== All {len(runs)} runs judged ===")
if __name__ == "__main__":
main()
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